cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Ab initio theory for two-neutrino and neutrinoless double-beta decay
Creators: name: Payne, Charlie G.
Publisher: name: University of British Columbia
Year: 2018

description: Although the complexity behind nuclear physics problems is often deemed too intensive even for modern supercomputers, non-perturbative ab initio (meaning "from first principles") many-body technologies have made significant strides towards efficiently modelling low-energy QCD structure. In particular, the similarity renormalization group, along with an "in-medium" reference state normal ordering (IM-SRG), has proven useful for making nuclear problems computationally manageable. This IM-SRG method translates chiral Hamiltonians, nuclear properties, and decays into a numerically tractable framework, whilst capturing bulk effects of forces via normal ordering. A decay that has generated much interest in the nuclear community is double-beta decay. The two-neutrino mode has evaded a proper theoretical treatment, due to a disconcerting puzzle known as "quenching." The neutrinoless mode (though still hypothetical) could unveil fundamental properties of the neutrino, such as its absolute mass and potential Majorana nature. In this dissertation, we will use IM-SRG, in a valence space shell model construction, to compute both the two-neutrino and neutrinoless double-beta decay of the doubly magic nucleus, Calcium-48. We conclude that the use of a fully ab initio method that models many-body effects, via IM-SRG, have decreased the two-neutrino double-beta decay nuclear matrix element by a factor of 3 (without any quenching factor), and the neutrinoless counterpart by roughly 20%, compared to the standard phenomenology for Calcium-48. This result has concerning experimental implications, since the half-life of a decay is proportional to the square of the inverse of the nuclear matrix element.
Transferrin and octaarginine modified dual-functional liposomes with improved cancer cell targeting and enhanced intracellular delivery for the treatment of ovarian cancer
Creators: name: Deshpande, Pranali
name: Jhaveri, Aditi
name: Pattni, Bhushan
name: Biswas, Swati
name: Torchilin, Vladimir
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Off-target effects of drugs severely limit cancer therapy. Targeted nanocarriers are promising to enhance the delivery of therapeutics to tumors. Among many approaches for active tumor-targeting, arginine-rich cell penetrating peptides (AR-CPP) and ligands specific to target over-expressed receptors on cancer-cell surfaces, are popular. Earlier, we showed that the attachment of an AR-CPP octaarginine (R8) to the surface of DOXIL® (Doxorubicin encapsulated PEGylated liposomes) improved cytoplasmic and nuclear DOX delivery that enhanced the cytotoxic effect in vitro and improved therapeutic efficacy in vivo. Here, we report on DOX-loaded liposomes, surface-modified with, R8 and transferrin (Tf) (Dual DOX-L), to improve targeting of A2780 ovarian carcinoma cells via the over-expressed transferrin receptors (TfRs) with R8-mediated intracellular DOX delivery. Flow cytometry analysis with fluorescently labeled DualL (without DOX) showed two-fold higher cancer-cell association than other treatments after 4 h treatment. Blocking entry pathways of R8 (macropinocytosis) and Tf (receptor-mediated endocytosis, RME) resulted in a decreased cancer-cell association of DualL. Confocal microscopy confirmed involvement of both entry pathways and cytoplasmic liposome accumulation with nuclear DOX delivery for Dual DOX-L. Dual DOX-L exhibited enhanced cytotoxicity in vitro and was most effective in controlling tumor growth in vivo in an A2780 ovarian xenograft model compared to other treatments. A pilot biodistribution study showed improved DOX accumulation in tumors after Dual DOX-L treatment. All results collectively presented a clear advantage of the R8 and Tf combination to elevate the therapeutic potential of DOX-L by exploiting TfR over-expression imparting specificity followed by endosomal escape and intracellular delivery via R8.
(E)-2-butene-1-thiol - Molecule of the Month February 2022 [Archived version]
Creators: name: Cotton, Simon
Publisher: name: figshare
Year: 2022
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for February 2022 about (E)-2-butene-1-thiol. It is a pdf archive version of the HTML webpage.
Plateau subduction, intraslab seismicity, and the Denali (Alaska) volcanic gap
Creators: name: Chuang, Yuling (Lindsay)
Publisher: name: University of British Columbia
Year: 2018

description: Tectonic tremors in Alaska (USA) are associated with subduction of the Yakutat plateau, but their origins are unclear due to lack of depth constraints. We have processed tremor recordings to extract low-frequency earthquakes (LFEs), and generated a set of six LFE waveform templates via iterative network matched filtering and stacking. The timing of impulsive P (compressional) wave and S (shear) wave arrivals on template waveforms places LFEs at 40–58 km depth, near the upper envelope of intraslab seismicity and immediately updip of increased levels of intraslab seismicity. S waves at near-epicentral distances display polarities consistent with shear slip on the plate boundary. We compare characteristics of LFEs, seismicity, and tectonic structures in central Alaska with those in warm subduction zones, and propose a new model for the region’s unusual intraslab seismicity and the enigmatic Denali volcanic gap (i.e., an area of no volcanism where expected). We argue that fluids in the Yakutat plate are confined to its upper crust, and that shallow subduction leads to hydromechanical conditions at the slab interface in central Alaska akin to those in warm subduction zones where similar LFEs and tremor occur. These conditions lead to fluid expulsion at shallow depths, explaining strike-parallel alignment of tremor occurrence with the Denali volcanic gap. Moreover, the lack of double seismic zone and restriction of deep intraslab seismicity to a persistent low-velocity zone are simple consequences of anhydrous conditions prevailing in the lower crust and upper mantle of the Yakutat plate.
title: Αξιοποίηση διαχρονικών μικρο-δεδομένων (στοιχείων έρευνας πάνελ) για την έρευνα των επιπτώσεων της πανδημίας Covid-19 στην Ευρώπη : το SHARE Corona Survey
title: Utilisation of panel micro data to study the impact of Covid-19 in Europe : the SHARE data
titleType: AlternativeTitle
Creators: name: Νγκρέσι, Ειρήνη
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2023
Subjects: subject: Επιπτώσεις
subject: Πανδημία

description: Η παρούσα διπλωματική εργασία έχει ως στόχο την διερεύνηση ύπαρξης συσχέτισης μεταξύ ευαλωτότητας (υγείας και οικονομική) και μέτρων προστασίας σε άτομα άνω των 50 ετών κατά την διάρκεια της πανδημίας. Για τον σκοπό αυτό αξιοποιούνται πληροφορίες από το όγδοο κύμα της πανευρωπαϊκής έρευνας SHARE που αφορά τον Covid-19 (Survey of Health, Ageing and Retirement in Europe). Τα χαρακτηριστικά που εξετάζονται είναι δημογραφικά, οικονομικά(οικονομική ευαλωτοτητα) και υγείας (ευαλωτοτητα υγείας). Στο πρώτο κεφάλαιο παρουσιάζονται ορισμοί που αφορούν την έννοια της ευαλωτότητας και γενικές πληροφορίες για την πανδημία Covid-19 και η σύνδεση αυτής με προ υπάρχουσες ασθένειες. Στο δεύτερο κεφάλαιο θα δώσουμε έμφαση στο πως κάθε χώρα αντιμετώπισε τον Covid-19. Βλέπουμε τα μέτρα που πήραν οι χώρες της Ευρώπης αλλά και το Ισραήλ. Καθώς τα δεδομένα μας πάρθηκαν από το SHARE το επόμενο κεφάλαιο αναφέρεται σε αυτό. Ξεκινώντας με το τι είναι το SHARE και αναφερθήκαμε και στα πλεονεκτήματα του. Για την ανάλυση των δεδομένων της έρευνάς SHARE γίνεται χρήση του στατιστικού πακέτου SPSS. Ειδικότερα, στο τέταρτο κεφάλαιο εξετάζεται μέσω της διδιάστατης ανάλυσης αν και σε τι βαθμό σχετίζεται η ευαλωτότητα με την λήψη μέτρων προστασίας. Το πέμπτο κεφάλαιο αποτελεί την κατακλείδα της παρούσας εργασίας, στο οποίο καταγράφονται τα κυριότερα συμπεράσματα της έρευνα. Πιο συγκεκριμένα οι γυναίκες έχουν χαμηλότερη πιθανότητα να λάβουν μέτρα προστασίας συγκριτικά με τους άνδρες και άτομα τα οποία χαρακτηρίσαμε οικονομικά ευάλωτα στον κόβιντ του 2020 και 2021 έχουν χαμηλότερη σχετική πιθανότητα να λάβουν μέτρα προστασίας συγκριτικά με τα άτομα που δεν ήταν οικονομικά ευάλωτοι, ενώ όσοι ήταν ευάλωτοι (ως προς την υγεία) είχαν και υψηλότερη σχετική πιθανότητα να λάβουν μέτρα προστασίας
Penetration enhancer-containing spanlastics (PECSs) for transdermal delivery of haloperidol: in vitro characterization, ex vivo permeation and in vivo biodistribution studies
Creators: name: Fahmy, Abdurrahman M.
name: El-Setouhy, Doaa Ahmed
name: Ibrahim, Ahmed B.
name: A. Habib, Basant
name: Tayel, Saadia A.
name: Bayoumi, Noha A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer

description: Haloperidol (Hal) is one of the widely used antipsychotic drugs. When orally administered, it suffers from low bioavailability due to hepatic first pass metabolism. This study aimed at developing Hal-loaded penetration enhancer-containing spanlastics (PECSs) to increase transdermal permeation of Hal with sustained release. PECSs were successfully prepared using ethanol injection method showing reasonable values of percentage entrapment efficiency, particle size, polydispersity index and zeta potential. The statistical analysis of the ex vivo permeation parameters led to the choice of F1L – made of Span® 60 and Tween® 80 at the weight ratio of 4:1 along with 1% w/v Labrasol® – as the selected formula (SF). SF was formulated into a hydrogel by using 2.5% w/v of HPMC K4M. The hydrogel exhibited good in vitro characteristics. Also, it retained its physical and chemical stability for one month in the refrigerator. The radiolabeling of SF showed a maximum yield by mixing of 100 µl of diluted formula with 50 µl saline having 200 MBq of 99mTc and containing 13.6 mg of reducing agent (NaBH4) and volume completed to 300 µl by saline at pH 10 for 10 min as reaction time. The biodistribution study showed that the transdermal 99mTc-SF hydrogel exhibited a more sustained release pattern and longer circulation duration with pulsatile behavior in the blood and higher brain levels than the oral 99mTc-SF dispersion. So, transdermal hydrogel of SF may be considered a promising sustained release formula for Hal maintenance therapy with reduced dose size and less frequent administration than oral formula.
Abundance analyses of helium-rich subluminous B stars
Creators: name: Naslim, N.
name: Jeffery, C. S.
name: Ahmad, A.
name: Behara, N. T.
name: Sahin, T.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The connection between helium-rich hot subdwarfs of spectral types O and B (He-sdB) has been relatively unexplored since the latter were found in significant numbers in the 1980's. In order to explore this connection further, we have analysed the surface composition of six He-sdB stars, including LB 1766, LB 3229, SB 21 (= Ton-S 137 = BPS 29503-0009), BPS 22940-0009, BPS 29496-0010, and BPS 22956-0094. Opacity-sampled line-blanketed model atmospheres have been used to derive atmospheric properties and elemental abundances. All the stars are moderately metal-poor compared with the Sun ([Fe/H] ~ -0.5). Four stars are nitrogen-rich, two of these are carbon-rich, and at least four appear to be neon-rich. The data are insufficient to rule out binarity in any of the sample. The surface composition and locus of the N-rich He-sdBs are currently best explained by the merger of two helium white dwarfs, or possibly by the merger of a helium white dwarf with a post-sdB white dwarf. C-rich He-sdBs require further investigation.
description: Accepted 2010 July 7
Single-electron effects in a coupled dot-ring system
Creators: name: Meier, L.
name: Fuhrer, A.
name: Ihn, Thomas
name: Ensslin, Klaus
name: Wegscheider, Werner
name: Bichler, Max
Publisher: name: Universität Regensburg
Year: 2004
Subjects: subject: 530 Physik
subject: 73.23.−b, 84.37.+q

description: Aharonov-Bohm oscillations are studied in the magnetoconductance of a micron-sized open quantum ring coupled capacitively to a Coulomb-blockaded quantum dot. As the plunger gate of the dot is modulated and tuned through a conductance resonance, the amplitude of the Aharonov-Bohm oscillations in the transconductance of the ring displays a minimum. We demonstrate that the effect is due to a single-electron screening effect, rather than to dephasing. Aharonov-Bohm oscillations in a quantum ring can thus be used for the detection of single charges.
Enteric-coated insulin microparticles delivered by lipopeptides of iturin and surfactin
Creators: name: Xing, Xiaoying
name: Zhao, Xiuyun
name: Ding, Jia
name: Liu, Dongming
name: Qi, Gaofu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Computational Biology

description: Surfactin, a lipopeptide produced by Bacillus species, has been used for the oral delivery of insulin. In this study, another lipopeptide of iturin was tested for its ability to orally delivery insulin alone or plus surfactin. Iturin could form co-precipitate with insulin at acidic pH values. After treatment by ultrasonification, the structure of coprecipitate was destroyed that led to a significant decrease in hypoglycemic effect after oral administration. Iturin weakly binds to (Kd = 257 μM) and induce insulin structure more compact that is favorable for insulin uptake by the intestine. After being coated with Acryl-Eze by lyophilization, the coprecipitate formed the spherical enteric-coated insulin microparticles delivered by iturin with a relative oral bioavailability of 6.84% in diabetic mice. For further improving oral hypoglycemic effect, surfactin was added to form the spherical enteric-coated insulin microparticles in a formulation containing insulin, Acryl-Eze, iturin and surfactin at a ratio of 1:1:0.5: 0.5 (w/w), with an insulin encapsulation efficiency of 66.22%. The enteric-coated insulin microparticles delivered by iturin plus surfactin showed a classical profile for controlled release in the intestine with a relative bioavailability of 7.67% after oral administration, which could effectively control the postprandial blood glucose at a level about 50% of the initial one just like the subcutaneous injection. Collectively, iturin plus surfactin is more efficient for oral delivering insulin than the sole one, and the resultant enteric-coated insulin microparticles are potential for the development of oral insulin to control postprandial blood glucose in diabetic patients.
In vivo nose-to-brain delivery of the hydrophilic antiviral ribavirin by microparticle agglomerates
Creators: name: Giuliani, Alessandro
name: Balducci, Anna Giulia
name: Zironi, Elisa
name: Colombo, Gaia
name: Bortolotti, Fabrizio
name: Lorenzini, Luca
name: Galligioni, Viola
name: Pagliuca, Giampiero
name: Scagliarini, Alessandra
name: Calzà, Laura
name: Sonvico, Fabio
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences

description: Nasal administration has been proposed as a potential approach for the delivery of drugs to the central nervous system. Ribavirin (RBV), an antiviral drug potentially useful to treat viral infections both in humans and animals, has been previously demonstrated to attain several brain compartments after nasal administration. Here, a powder formulation in the form of agglomerates comprising micronized RBV and spray-dried microparticles containing excipients with potential absorption enhancing properties, i.e. mannitol, chitosan, and α-cyclodextrin, was developed for nasal insufflation. The agglomerates were characterized for particle size, agglomeration yield, and ex vivo RBV permeation across rabbit nasal mucosa as well as delivery from an animal dry powder insufflator device. Interestingly, permeation enhancers such as chitosan and mannitol showed a lower amount of RBV permeating across the excised nasal tissue, whereas α-cyclodextrin proved to outperform the other formulations and to match the highly soluble micronized RBV powder taken as a reference. In vivo nasal administration to rats of the agglomerates containing α-cyclodextrin showed an overall higher accumulation of RBV in all the brain compartments analyzed as compared with the micronized RBV administered as such without excipient microparticles. Hence, powder agglomerates are a valuable approach to obtain a nasal formulation potentially attaining nose-to-brain delivery of drugs with minimal processing of the APIs and improvement of the technological and biopharmaceutical properties of micronized API and excipients, as they combine optimal flow properties for handling and dosing, suitable particle size for nasal deposition, high surface area for drug dissolution, and penetration enhancing properties from excipients such as cyclodextrins.
The targum (1881:Jan. 7 - 1881:Jan. 28)
Creators: name: No Name Supplied
Publisher: name: Targum Association
Year: 1881

description: Some University historians indicate that the Targum was first published as an annual in 1867, but of this we have no extant evidence. In January 1869, the Targum as we now know it, made its appearance as a monthly paper that concerned itself with student “literary contributions” and college news as well as serving as a vehicle for bringing news to alumni and the general public. The newspaper, which originally was for sale, varied in frequency over the years as did its title (The Targum, Rutgers Targum, Rutgers Daily Targum, and Daily Targum). The newspaper has continuously been published since 1869 with the exception of 19 months during the second world war, between February 1944 and October 1945. The Targum was published by the students of Rutgers College, and later Rutgers University—New Brunswick represented through the years as the Targum Association, Rutgers Targum Association, and Rutgers College Targum. As a student organization, the Targum operated under the oversight of the dean of students and student government but in October 1980, the Targum became an independent college paper.
Local Stellar Kinematics from RAVE Data: I. Local Standard of Rest
Creators: name: Coskunoglu, B.
name: Ak, S.
name: Bilir, S.
name: Karaali, S.
name: Yaz, E.
name: Gilmore, G.
name: Seabroke, G. M.
name: Bienayme, O.
name: Bland-Hawthorn, J.
name: Campbell, R.
name: Freeman, K. C.
name: Gibson, B.
name: Grebel, E. K.
name: Munari, U.
name: Navarro, J. F.
name: Parker, Q. A.
name: Siebert, A.
name: Siviero, A.
name: Steinmetz, M.
name: Watson, F. G.
name: Wyse, R. F. G.
name: Zwitter, T.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We analyze a sample of 82850 stars from the RAVE survey, with well-determined velocities and stellar parameters, to isolate a sample of 18026 high-probability thin-disc dwarfs within 600 pc of the Sun. We derive space motions for these stars, and deduce the solar space velocity with respect to the Local Standard of Rest. The peculiar solar motion we derive is in excellent agreement in radial $U_{\odot}$ and vertical $W_{\odot}$ peculiar motions with other recent determinations. Our derived tangential peculiar velocity, $V_{\odot}$ agrees with very recent determinations, which favour values near 13 km s$^{-1}$, in disagreement with earlier studies. The derived values are not significantly dependent on the comparison sample chosen, or on the method of analysis. The local galaxy seems very well dynamically relaxed, in a near symmetric potential.
description: 9 pages, including 9 figures and 3 tables, accepted for publication in MNRAS
Between Cultural Essence and Stereotype. A Visual Analysis of Childish Gambino’s “This is America”
Creators: name: Mondillo, Mirko
name: De Majo, Claudio
Publisher: name: SigMa - Rivista di Letterature comparate, Teatro e Arti dello spettacolo
Year: 2021

description: Focusing our attention on its setting, its choreographic choices, the protagonist’s gestures, the stage costumes and through the lenses of visual and communication, we develop a critical analysis illustrating the political and social discourses provided by This Is America. As the song’s lyrics do not explicitly deal with topics such as gun control, police brutality and racism, this essay focuses on visual theory in order to assess the emergence of these themes along the visual images of the videoclip. In this sense, this research effort focuses on two main critical aspects: on the one hand, it assesses the visual strategies adopted by Gambino and Murai in order to produce a critical discourse on race relations in America without falling into the usual clichés associated to Black culture. On the other hand, it looks at the multiple cultural references to black culture, from pop music to the cinematic production of Spike Lee and Jordan Peele, and how these are weaved into the video clip of This is America, though the adoption of inflated images, allegories, metaphors and symbols. In this essay, we provide a visual analysis of Childish Gambino video clip This is America, directed by Hiro Murai in 2018. We attempt to understand the multiple interpretative layers and contents of Gambino’s video and song.
description: SigMa - Rivista di Letterature comparate, Teatro e Arti dello spettacolo, N. 5 (2021)
Book Review: Bourn, D. (ed.) (2020). The Bloomsbury Handbook of Global Education and Learning
Creators: name: Coelho, La Salete
name: Franch, Sara
Publisher: name: JSSE - Journal of Social Science Education
Year: 2020

description: JSSE - Journal of Social Science Education, Vol. 19 No. 4 (2020): Global education at crossroads
Vibrational Instabilities in Resonant Electron Transport through Single-Molecule Junctions
Creators: name: Härtle, R.
name: Thoss, M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We analyze various limits of vibrationally coupled resonant electron transport in single-molecule junctions. Based on a master equation approach, we discuss analytic and numerical results for junctions under a high bias voltage or weak electronic-vibrational coupling. It is shown that in these limits the vibrational excitation of the molecular bridge increases indefinitely, i.e. the junction exhibits a vibrational instability. Moreover, our analysis provides analytic results for the vibrational distribution function and reveals that these vibrational instabilities are related to electron-hole pair creation processes.
description: 19 pages, 3 figures
Book Review: Helmuth Hartmeyer, H. & Wegimont, L. (ed.). (2016). Global Education in Europe Revisited. Strategies and Structures - Policy, Practice and Challenges
Creators: name: Affolderbach, Martin
Publisher: name: JSSE - Journal of Social Science Education
Year: 2020

description: JSSE - Journal of Social Science Education, Vol. 19 No. 4 (2020): Global education at crossroads
Considerations and Results in Multimedia and DVB Application Development on Philips Nexperia Platform
Creators: name: Arsinte, Radu
name: Ilioaei, Ciprian
Publisher: name: arXiv
Year: 2011
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: This paper presents some experiments regarding applications development on high performance media processors included in Philips Nexperia Family. The PNX1302 dedicated DVB-T kit used has some limitations. Our work has succeeded to overcome these limitations and to make possible a general-purpose use of this kit. For exemplification two typical applications, important both for multimedia and DVB, are analyzed: MPEG2 video stream decoding and MP3 audio decoding. These original implementations are compared (in speed, memory requirements and costs) with Philips Nexperia Library.
description: 3 pages, 1 figure
L’ultima lettura di Freud, o patologia della vita sociale
Creators: name: Brooks, Peter
name: Tortonese, Paolo
Publisher: name: SigMa - Rivista di Letterature comparate, Teatro e Arti dello spettacolo
Year: 2021

description: L’articolo parte dalla constatazione che in Freud, come in Balzac, è presente una teoria dei segni che rimanda ai legami tra pensiero, volontà e movimento nell’essere umano. Più in generale in opere come La Psicopatologia della vita quotidiana o la Pathologie de la vie sociale, all’interno dell’elaborazione di una semiotica globale della vita quotidiana, viene rivendicata la possibilità di risalire dagli atti di parola e dai gesti quotidiani apparentemente più insignificanti ai loro significati più profondi considerandoli come sintomi. Tuttavia le teorizzazioni di Balzac e di Freud finiscono per oltrepassare ogni semiotica razionalmente fondata. La loro pretesa di comprensione totale del gesto e dell’atto involontario non può essere contenuta all’interno di un mero esercizio di osservazione immediata: essa va al di là e implica la considerazione di istanze mitiche e figurali che operano sotto la soglia della percezione umana. Così una tale semiotica ambiziosa e onnicomprensiva implica un’ineliminabile componente allucinatoria. E ciò non diversamente dall’universo di manifestazioni sintomatiche sociali e psicologiche a cui pretenderebbe di assegnare un ordine razionale.
description: SigMa - Rivista di Letterature comparate, Teatro e Arti dello spettacolo, N. 5 (2021)
A Statistical Mechanical Approach for the Computation of the Climatic Response to General Forcings
Creators: name: Lucarini, Valerio
name: Sarno, Stefania
Publisher: name: arXiv
Year: 2010
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Chaotic Dynamics (nlin.CD)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The climate belongs to the class of non-equilibrium forced and dissipative systems, for which most results of quasi-equilibrium statistical mechanics, including the fluctuation-dissipation theorem, do not apply. We show for the first time how the Ruelle linear response theory, developed for studying rigorously the impact of perturbations on general observables of non-equilibrium statistical mechanical systems, can be applied to analyze the climatic response. We choose as test bed the Lorenz 96 model, which has a well-recognized prototypical value. We recapitulate the main aspects of the response theory and propose some new results. We then analyze the frequency dependence of the response of both local and global observables to perturbations with localized as well as global spatial patterns. We derive analytically the asymptotic behaviour, validity of Kramers-Kronig relations, and sum rules for the susceptibilities, and related them to parameters describing the unperturbed properties of the system. We verify the theoretical predictions from the outputs of the simulations with great precision. The theory is used to explain differences in the response of local and global observables, in defining the intensive properties of the system and in generalizing the concept of climate sensitivity to all time scales. We also show how to reconstruct the linear Green function, which maps perturbations of general time patterns into changes in the expectation value of the considered observable. Finally, we propose a general methodology to study Climate Change problems by resorting to few, well selected simulations and discuss the specific case of surface temperature response to changes of the $CO_2$ concentration. This approach may provide a radically new perspective to study rigorously the problem of climate sensitivity and climate change.
description: 56 pages, 9 figures [new version with one added section and improved figures]
Colloidal particles in liquid crystal films and at interfaces
Creators: name: Tasinkevych, Mykola
name: Andrienko, Denis
Publisher: name: arXiv
Year: 2010
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: This mini-review discusses the recent contribution of theoretical and computational physics as well as experimental efforts to the understanding of the behavior of colloidal particles in confined geometries and at liquid crystalline interfaces. Theoretical approaches used to study trapping, long- and short-range interactions, and assembly of solid particles and liquid inclusions are outlined. As an example, an interaction of a spherical colloidal particle with a nematic-isotropic interface and a pair interaction potential between two colloids at this interface are obtained by minimizing the Landau-de Gennes free energy functional using the finite-element method with adaptive meshes.
description: 22 pages, 10 figures
Preparation of a mesoporous silica-based nano-vehicle for dual DOX/CPT pH-triggered delivery
Creators: name: Llinàs, Maria C.
name: Martínez-Edo, Gabriel
name: Cascante, Anna
name: Porcar, Irene
name: Borrós, Salvador
name: Sánchez-García, David
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: A dual doxorubicin/camptothecin (DOX/CPT) pH-triggered drug delivery mesoporous silica nanoparticle (MSN)-based nano-vehicle has been prepared. In this drug-delivery system (DDS), CPT is loaded inside the pores of the MSNs, while DOX is covalently attached to the surface of an aldehyde-functionalized MSN through a dihydrazide–polyethylene glycol chain. Thus, DOX and the linker act as pH-sensitive gatekeeper. The system is versatile and easy to assemble, not requiring the chemical modification of the drugs. While at physiological conditions the release of the drugs is negligible, at acidic pH a burst release of DOX and a gradual release of CPT take place. In vitro cytotoxicity tests have demonstrated that this DDS can deliver efficiently DOX and CPT for combination therapy.
Educating Pre-Service Teachers on Global Citizenship: Research Perspectives from a Preliminary Study in the Italian context
Creators: name: Damiani, Valeria
Publisher: name: JSSE - Journal of Social Science Education
Year: 2020

description: Purpose: To analyse prospective teachers’ interest in global citizenship education (GCE) and the inclusion of GCE-related issues in a teaching programme in Italy. Design/methodology/approach: Administration of an online questionnaire to pre-service teachers attending a course for becoming pre-primary and primary school teachers, and discussion of the main results. Findings: Pre-service teachers are provided with basic discipline-related and pedagogical knowledge that is not directly linked to GCE but allows the implementation of GCE in their classrooms. Findings also suggest the influence on prospective teachers’ self-preparedness and confidence of the learning opportunities that occur in non-formal and informal contexts. Research implications: There should be further analysis of the relations between GCE and students’ interests, their opportunities to learn about GCE, their degree of global engagement, and civic and citizenship education for the enhancement of pre-service training curricula.
description: JSSE - Journal of Social Science Education, Vol. 19 No. 4 (2020): Global education at crossroads
EXPLORING RURAL ENTREPRENEURSHIP: MOTIVATIONS AND PROFILES IN KERALA
Creators: name: DEEPTHI NAIR H V
name: Dr. V. MAHESWARI
Publisher: name: Zenodo
Year: 2023
Subjects: Rural Entrepreneurs, Entrepreneurial Profile and Rural Entrepreneurial Motivation.

description: Abstract
This study sought to uncover the motivations driving rural entrepreneurship, specifically within the context of Kerala rural entrepreneurial profiles. By analyzing and interpreting data gathered from 270 rural entrepreneurs, this research provided invaluable insights into the relationship between entrepreneurial motivations and profiles within rural environments. In order to better understand the relationship between entrepreneurial profiles and factors including social anchoring, intellectual drive, autonomy, and an enabling environment, the researcher formulated and evaluated hypotheses. Her results revealed nine cases that supported the null hypothesis while twelve favoring alternative hypotheses; suggesting an association between specified motivators and entrepreneurial profiles.
Refractive index spectral dependence, Raman and transmission spectra of high-purity $^{28}$Si, $^{29}$Si, $^{30}$Si, and $^{nat}$Si single crystals
Creators: name: Plotnichenko, V. G.
name: Nazaryants, V. O.
name: Kryukova, E. B.
name: Koltashev, V. V.
name: Sokolov, V. O.
name: Dianov, E. M.
name: Gusev, A. V.
name: Gavva, V. A.
name: Kotereva, T. V.
name: Churbanov, M. F.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Precise measurement of the refractive index of stable silicon isotopes $^{28}$Si, $^{29}$Si, $^{30}$Si single crystals with enrichments above 99.9 at.% and a silicon single crystal $^{nat}$Si of natural isotopic composition is performed with the Fourier-transform interference refractometry method from 1.06 to more than 80 mkm with 0.1 cm$^{-1}$ resolution and accuracy of $2 \times 10^{-5} ... 1 \times 10^{-4}$. The oxygen and carbon concentrations in all crystals are within $5 \times 10^{15}$ cm$^{-3}$ and the content of metal impurities is $10^{-5} ... 10^{-6}$ at.%. The peculiar changes of the refractive index in the phonon absorption region of all silicon single crystals are shown. The coefficients of generalized Cauchy dispersion function approximating the experimental refractive index values all over the measuring range are given. The transmission and Raman spectra are also studied.
Nano-engineered microcapsules boost the treatment of persistent pain
Creators: name: Kopach, Olga
name: Zheng, Kayiu
name: Dong, Luo
name: Sapelkin, Andrei
name: Voitenko, Nana
name: Sukhorukov, Gleb B.
name: Rusakov, Dmitri A.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Persistent pain remains a major health issue: common treatments relying on either repeated local injections or systemic drug administration are prone to concomitant side-effects. It is thought that an alternative could be a multifunctional cargo system to deliver medicine to the target site and release it over a prolonged time window. We nano-engineered microcapsules equipped with adjustable cargo release properties and encapsulated the sodium-channel blocker QX-314 using the layer-by-layer (LbL) technology. First, we employed single-cell electrophysiology to establish in vitro that microcapsule application can dampen neuronal excitability in a controlled fashion. Secondly, we used two-photon excitation imaging to monitor and adjust long-lasting release of encapsulated cargo in target tissue in situ. Finally, we explored an established peripheral inflammation model in rodents to find that a single local injection of QX-314-containing microcapsules could provide robust pain relief lasting for over a week. This was accompanied by a recovery of the locomotive deficit and the amelioration of anxiety in animals with persistent inflammation. Post hoc immunohistology confirmed biodegradation of microcapsules over a period of several weeks. The overall remedial effect lasted 10–20 times longer than that of a single focal drug injection. It depended on the QX-314 encapsulation levels, involved TRPV1-channel-dependent cell permeability of QX-314, and showed no detectable side-effects. Our data suggest that nano-engineered encapsulation provides local drug delivery suitable for prolonged pain relief, which could be highly advantageous compared to existing treatments.
Concerning labour markets and the commodification of social difference in the Alberta oil sands
Creators: name: MacArthur, Ewen
Publisher: name: University of British Columbia
Year: 2018

description: In this thesis, I consider ethnographic conversations I had during fieldwork in Fort McMurray and Edmonton, Alberta, Canada, in 2016 with two sets of workers: Albertan trades-workers employed in the oil sands (pipe-fitters, welders and boilermakers) and Filipino/a Temporary Foreign Workers (TFWs) employed in the local service sector (cooks, caregivers and kitchen helpers). I analyse these workers’ self-reflections on their own work routines as providing a sightline into the ways labour market processes and regulatory frameworks are manifest in and negotiated through their lives. I draw especially on the theories of Karl Polanyi and Karl Marx in my analysis. Through ethnography I also show how the labour market processes these thinkers analyse shape, and are shaped by, social differences they each tend to neglect (e.g. nationality, citizenship, migration status, race, ethnicity, gender), and which more recent post-colonial, feminist, and critical race theorists have emphasised. Hence from the Albertan context, I conceptualise how state-regulated labour markets re-fashion, and are re-fashioned by, the cultural identities of workers. I show how local labour market processes re-make and aggravate social differences between Albertan trades-workers and Filipino/a TFWs in Alberta, in ways that are not superficially or simply motivated by forms of discrimination (e.g. xenophobia, racism, sexism), but which nonetheless agitate and divide an emergent “precariat” (Standing 2011). I hope this thesis can provide the basis for further ethnographic and comparative research.
title: Theory of Mind in Human-Robot-Communication: Appreciated or not?
Creators: name: Benninghoff, Brenda
name: Kulms, Philipp
name: Hoffmann, Laura
name: Krämer, Nicole
Publisher: name: DuEPublico: Duisburg-Essen Publications Online, University of Duisburg-Essen, Germany
Year: 2013

description: Social robots play a more and more important role in our society. For better acceptance and more fluent interactions between humans and robots it is generally assumed that implementing human-like cognitive functions within robots is helpful. A between-subjects experiment (N = 40) was conducted to in-vestigate whether implementing a theory of mind within a humanoid robot will lead to higher acceptance of the robot. Theory of mind is considered one of the most essential prerequisites for interpersonal interac-tion in human-human interaction. Researchers argue that theory of mind enhanced robots capturing other person’s goals, beliefs, feelings, and intentions will perform significantly better. Subjects were presented videos of interactions with a humanoid robot that either possessed or did not possess theory of mind abili-ties. Results indicate subjects acknowledged the fact that a robot showing theory of mind abilities such as perspective taking followed its own intentions; that it understood the way another person behaves; that it was aware of another person’s thoughts, beliefs, and feelings. Accordingly, the robot was rated more sym-pathetic and higher on social attractiveness but not on task attractiveness. Implications of these results as well as limitations are discussed.
Raman light scattering study and microstructural analysis of epitaxial films of the electron-doped superconductor La_{2-x}Ce_{x}CuO_{4}
Creators: name: Rahlenbeck, M.
name: Wagenknecht, M.
name: Tsukada, A.
name: Koelle, D.
name: Kleiner, R.
name: Keimer, B.
name: Ulrich, C.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We present a detailed temperature-dependent Raman light scattering study of optical phonons in molecular-beam-epitaxy-grown films of the electron-doped superconductor La_{2-x}Ce_{x}CuO_{4} close to optimal doping (x ~ 0.08, T_c = 29 K and x ~ 0.1, T_c = 27 K). The main focus of this work is a detailed characterization and microstructural analysis of the films. Based on micro-Raman spectroscopy in combination with x-ray diffraction, energy-dispersive x-ray analysis, and scanning electron microscopy, some of the observed phonon modes can be attributed to micron-sized inclusions of Cu_{2}O. In the slightly underdoped film (x ~ 0.08), both the Cu_{2}O modes and others that can be assigned to the La_{2-x}Ce_{x}CuO_{4} matrix show pronounced softening and narrowing upon cooling below T ~ T_c. Based on control measurements on commercial Cu_{2}O powders and on a comparison to prior Raman scattering studies of other high-temperature superconductors, we speculate that proximity effects at La_{2-x}Ce_{x}CuO_{4}/Cu_{2}O interfaces may be responsible for these anomalies. Experiments on the slightly overdoped La_{2-x}Ce_{x}CuO_{4} film (x ~ 0.1) did not reveal comparable phonon anomalies.
description: 7 pages, 8 figures
Quantum counterpart of spontaneously broken classical PT symmetry
Creators: name: Bender, Carl M.
name: Jones, Hugh F.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The classical trajectories of a particle governed by the PT-symmetric Hamiltonian $H=p^2+x^2(ix)^ε$ ($ε\geq0$) have been studied in depth. It is known that almost all trajectories that begin at a classical turning point oscillate periodically between this turning point and the corresponding PT-symmetric turning point. It is also known that there are regions in $ε$ for which the periods of these orbits vary rapidly as functions of $ε$ and that in these regions there are isolated values of $ε$ for which the classical trajectories exhibit spontaneously broken PT symmetry. The current paper examines the corresponding quantum-mechanical systems. The eigenvalues of these quantum systems exhibit characteristic behaviors that are correlated with those of the associated classical system.
description: 11 pages, 7 figures
Critical and Postcolonial Perspectives on Global Education: The Case of Poland
Creators: name: Kuleta-Hulboj, Magdalena
Publisher: name: JSSE - Journal of Social Science Education
Year: 2020

description: Purpose: This paper aims to contribute to the academic debate on postcolonial perspectives on global education problematising the context of global education in Poland, a former Second World country that does not fit to Global North-Global South dichotomy. Approach: The article explores global education in Poland from a critical and postcolonial perspective. It examines both supra-national factors shaping global education nowadays (like migrations, cosmopolitan turn, growing right-wing populism, the culture of measurement) and specific Polish context as a country not only “in-between”, but with the experience of “triple coloniality”. Findings: I argue that taking into consideration this complexity and multilayeredness of the Polish situation, together with more general, not country-specific factors, can offer new insights and understandings of global education in Poland. It is a necessary step to decolonise global education and make it more inclusive.
description: JSSE - Journal of Social Science Education, Vol. 19 No. 4 (2020): Global education at crossroads
Importance of Fermi surface topology for high temperature superconductivity in electron-doped iron arsenic superconductors
Creators: name: Liu, Chang
name: Palczewski, A. D.
name: Kondo, Takeshi
name: Fernandes, R. M.
name: Mun, E. D.
name: Hodovanets, H.
name: Thaler, A. N.
name: Schmalian, J.
name: Bud'ko, S. L.
name: Canfield, P. C.
name: Kaminski, A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We used angle resolved photoemission spectroscopy and thermoelectric power to study the poorly explored, highly overdoped side of the phase diagram of Ba(Fe1-xCox)2As2 high temperature superconductor. Our data demonstrate that several Lifshitz transitions - topological changes of the Fermi surface - occur for large x. Tc starts to decrease with doping when the cylindrical, central hole pocket changes to ellipsoids centering at the Z point, and goes to zero before these ellipsoids disappear around x = 0.2. Changes in thermoelectric power occur at similar x-values. Beyond this doping level the central pocket changes to electron-like and superconductivity does not exist. Our observations reveal the crucial importance of the underlying Fermiology in this class of materials. A necessary condition for superconductivity is the presence of the central hole pockets rather than perfect nesting between central and corner pockets.
description: Typo in names corrected. Minor changes to the text
A convex model for non-negative matrix factorization and dimensionality reduction on physical space
Creators: name: Esser, Ernie
name: Möller, Michael
name: Osher, Stanley
name: Sapiro, Guillermo
name: Xin, Jack
Publisher: name: arXiv
Year: 2011
Subjects: subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: A collaborative convex framework for factoring a data matrix $X$ into a non-negative product $AS$, with a sparse coefficient matrix $S$, is proposed. We restrict the columns of the dictionary matrix $A$ to coincide with certain columns of the data matrix $X$, thereby guaranteeing a physically meaningful dictionary and dimensionality reduction. We use $l_{1,\infty}$ regularization to select the dictionary from the data and show this leads to an exact convex relaxation of $l_0$ in the case of distinct noise free data. We also show how to relax the restriction-to-$X$ constraint by initializing an alternating minimization approach with the solution of the convex model, obtaining a dictionary close to but not necessarily in $X$. We focus on applications of the proposed framework to hyperspectral endmember and abundances identification and also show an application to blind source separation of NMR data.
description: 14 pages, 9 figures. EE and JX were supported by NSF grants {DMS-0911277}, {PRISM-0948247}, MM by the German Academic Exchange Service (DAAD), SO and MM by NSF grants {DMS-0835863}, {DMS-0914561}, {DMS-0914856} and ONR grant {N00014-08-1119}, and GS was supported by NSF, NGA, ONR, ARO, DARPA, and {NSSEFF.}