cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of First evidence showing that Pepper vein yellows virus P4 protein is a movement protein
Creators: name: Li, Sangsang
name: Su, Xianyan
name: Luo, Xiangwen
name: Zhang, Yu
name: Zhang, Deyong
name: Du, Jiao
name: Zhang, Zhanhong
name: OuYang, Xian
name: Zhang, Songbai
name: Liu, Yong
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Additional file 1: Table S1. Primers for constructing P4 and P4 variants expressing vector. Table S2. Movement of PeVYV P4 between epidermal cells in N. benthamiana leaves at 24 hpi. Figure S1. Transmembrane domains predicted in the PeVYV P4 protein by various algorisms. Positions of the predicted transmembrane domains are indicated. Figure S2. The P4-YFP fusion could move between epidermal cells in N. benthamiana leaves. N. benthamiana leaves were infiltrated with agrobacterium cultures carrying pP4-YFP or pPDLP8-YFP. The infiltrated leaves were harvested at 24 hpi and examined under a confocal microscope. Images showing PDLP8-YFP expression are shown in the lower panel and images showing P4-YFP expression are shown in the upper panel. Bars, 20 μm.
title: CT-guided transthoracic fine needle aspirations of 781 pulmonary lesions: risk factors for pneumothorax including the attending radiologist and cytologist.
Creators: name: Rasmark, Kristina
Publisher: name: European Society of Thoracic Imaging
Year: 2019
Subjects: subject: Cancer
subject: Puncture
subject: CT
subject: Thorax
subject: Interventional non-vascular

description: Purpose Methods Materials Results Conclusion References Personal Information
description: Purpose: Transthoracic CT-guided Fine Needle Aspiration (FNA) is a well-established technique for diagnosis of lung lesions. The method varies between sites[1].At our institution the FNAs of lung lesions are a joint venture where a radiologist places a...
title: Tumoral and peritumoral CT radiomics for the prediction of ALK (anaplastic lymphoma kinase) and EGFR (epidermal growth factor receptor) mutation in lung adenocarcinoma
Creators: name: Seo, Joon Beom
Publisher: name: European Society of Thoracic Imaging
Year: 2019
Subjects: subject: Cancer
subject: CAD
subject: CT-Quantitative
subject: CT
subject: Thorax

description: Purpose Methods Materials Results Conclusion References Personal Information
description: Purpose: With the introduction of genomic profiling in clinical practice, cancer treatment decisions are increasingly based not only on the patient’s clinical chracateristics and tumor morphology but also on individual mutational profile. Mutational...
Immune checkpoint blockade as a potential therapeutic target in non-small cell lung cancer
Creators: name: Jiali Yang
name: Chen, Juan
name: Wei, Jun
name: Xiaoming Liu
name: Cho, William C.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Introduction: The recent emergence of immune checkpoint blockade therapy and the progression of immunobiology in cancer have spurred an increasing interest in the immunotherapy for advanced non-small cell lung cancer (NSCLC). Immune checkpoint inhibitors (ICIs), designed to directly target immune inhibitory molecules, have demonstrated efficacy in the treatment of patients with advanced NSCLC. Areas covered: In the present article, the authors summarize the mechanism, efficacy and safety of major ICIs for the treatment of advanced or metastatic NSCLC. Combinations of different ICIs or conventional therapy and/or targeted agents for NSCLC treatment in clinical trials are also updated. In addition, immune-related adverse events and the roles of inhibitory immune checkpoint molecules as potential biomarkers in the immune checkpoint blockade therapy for NSCLC are emphatically elucidated. Expert opinion: Immunotherapies targeting the immune checkpoint pathways have shown potential to generate durable responses and improve survival for NSCLC patients. Although the toxicity profile of this immunotherapy is manageable, immune-related adverse events and drug resistance may cause therapeutic failure. Therefore, a better understanding of the mechanisms underpinning its function and the potential side effects of ICIs, as well as the identification of predictive biomarkers for patient selection are essential.
Influence of Dopamine D2-type Receptors on Motor Behaviors and Conditioning in the Green Tree Frog, Hyla cinerea
Creators: name: Creighton, Anna
Publisher: name: Georgia State University
Year: 2013

description: Dopamine modulates a range of behaviors that include motor processes, learning, and incentive motivation. Neuroanatomical research supports conservation of dopaminergic populations in the midbrain across vertebrate species, however, less evidence is available for dopamine receptor distributions and function. In order to test the behavioral role of dopamine in a conserved dopaminergic system, the effects of D2-type receptor manipulation on motor behaviors were examined in the anuran amphibian green tree frog, Hyla cinerea. In two different experiments, frogs were treated with a D2 receptor-specific drug, quinpirole or haloperidol, and exposed to a testing session to measure changes in motor behaviors. Quinpirole generally inhibited some motor behaviors, while haloperidol generally stimulated some motor behaviors, as predicted based on receptor mechanisms. A pattern of performance improvement also appeared in frogs in each experiment. Overall, the results support general conservation of DA in motor processes in vertebrate species.
Additional file 2: of Long non-coding RNA DANCR promotes malignant phenotypes of bladder cancer cells by modulating the miR-149/MSI2 axis as a ceRNA
Creators: name: Zhan, Yonghao
name: Chen, Zhicong
name: Li, Yifan
name: He, Anbang
name: He, Shiming
name: Gong, Yanqing
name: Li, Xuesong
name: Zhou, Liqun
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Table2. The primer sequences included in this study. (DOCX 16 kb)
Macrholaspis recki
Creators: name: Kontschán, Jenő
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Macrochelidae
Macrholaspis
Macrholaspis recki

description: Macrholaspis recki (Bregetova and Koroleva, 1960)
 Macrocheles recki Bregetova and Koroleva, 1960: 104.
 Occurrences. Tátika (Erőss and Mahunka, 1971a), Annahegy, Ferihegy, Ecséd, Budaörs, Velence, Törek, Letenye (Kontschán et al., 2015b).
description: Published as part of Kontschán, Jenő, 2020, Checklist of the Hungarian species of family Macrochelidae (Acari: Mesostigmata), pp. 7-17 in Acarological Studies 2 (1) on page 9
Comparison of bone-anchored prostheses and socket prostheses for patients with a lower extremity amputation: a systematic review
Creators: name: Leijendekkers, Ruud A.
name: Hinte, Gerben Van
name: Frölke, Jan Paul
name: Meent, Hendrik Van De
name: Sanden, Maria W.G. Nijhuis-Van Der
name: J. Bart Staal
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Science Policy
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Purpose: This study aimed to provide an overview of a) the used measurement instruments in studies evaluating effects on quality of life (QoL), function, activity and participation level in patients with a lower extremity amputation using bone-anchored prostheses compared to socket prostheses and b) the effects themselves. Method: A systematic literature search was conducted in MEDLINE, Cochrane, EMBASE, CINAHL and Web of Science. Included studies compared QoL, function, activity and/or participation level in patients with bone-anchored or socket prostheses. A best-evidence synthesis was performed. Results: Out of 226 studies, five cohort and two cross-sectional studies were eligible for inclusion, all had methodological shortcomings. These studies used 10 different measurement instruments and two separate questions to assess outcome. Bone-anchored prostheses were associated with better condition-specific QoL and better outcomes on several of the physical QoL subscales, outcomes on the physical bodily pain subscale were inconclusive. Outcomes on function and activity level increased, no change was found at participation level. The level of evidence was limited. Conclusions: There is a need for a standard set of instruments. There was limited evidence that bone-anchored prostheses resulted in higher QoL, function and activity levels than socket prostheses, in patients with socket-related problems. Implications for RehabilitationUse of bone-anchored prostheses in combination with intensive outpatient rehabilitation may improve QoL, function and activity level compared with socket prosthesis use in patients with a transfemoral amputation and socket-related problems.All clinicians and researchers involved with bone-anchored prostheses should use and publish data on QoL, function, activity and participation level.There needs to be an agreement on a standard set of instruments so that interventions for patients with a lower extremity amputation are assessed consistently. Use of bone-anchored prostheses in combination with intensive outpatient rehabilitation may improve QoL, function and activity level compared with socket prosthesis use in patients with a transfemoral amputation and socket-related problems. All clinicians and researchers involved with bone-anchored prostheses should use and publish data on QoL, function, activity and participation level. There needs to be an agreement on a standard set of instruments so that interventions for patients with a lower extremity amputation are assessed consistently.
Role of the Nucleus Accumbens and Mesolimbic Dopamine System in Modulating the Memory of Social Defeat in Male Syrian Hamsters (Mesocricetus auratus)
Creators: name: Luckett, Cloe
Publisher: name: Georgia State University
Year: 2014

description: Psychological stressors such as social stress and bullying are prevalent in today's society.  Disorders such as PTSD, depression and social anxiety disorder can be either caused or exacerbated by social stress and treatment options are not always effective in providing relief for these disorders.  Our laboratory studies a form of social stress termed conditioned defeat, whereby a defeated Syrian hamster no longer displays species-typical territorial aggression but instead is submissive and defensive toward an intruder in its own cage.  We hypothesized that the nucleus accumbens is a necessary component of the circuit mediating the acquisition and expression of conditioned defeat and that dopamine is necessary within the nucleus accumbens for inducing memory processes as well as expression of behavioral responses to stressful situations.  We also hypothesized that defeat activates dopaminergic and/or nondopaminergic neurons in the ventral tegmental area (VTA) and that dopamine released by neurons projecting from the VTA to the nucleus accumbens and basolateral amygdala (BLA) increases neuronal activation of these structures during defeat.  We found that dopamine, but not GABA, modulates memory of social defeat within the nucleus accumbens.  However, GABA does affect the expression of behavioral responses to social defeat.  Defeat also increased Fos activation of non-dopaminergic neurons, but it did not increase activation of dopaminergic neurons.  Baclofen infusion into the VTA prior to defeat, which was hypothesized to specifically inhibit dopaminergic neurons, did not affect Fos activation within the nucleus accumbens and the basolateral amygdala.  These experiments determined that dopamine does modulate memory of social defeat within the nucleus accumbens, but it is currently unclear what the source of this dopamine is.  Future experiments are planned to determine this source of dopamine that could be a target of treatment for disorders that are caused or exacerbated by social stress.
"From Norman estate centre to Angevin town": Kingston upon Thames urban origins
Creators: name: Hawkins, Duncan
Publisher: name: Archaeology Data Service
Year: 2003

description: London Archaeologist, 10 (4), 95-101
description: Rapid growth in the second half of the twelfth century makes the town's origins wholly consistent with the pattern of urbanization seen across much of southern and central England between the Norman Conquest and the mid-thirteenth century.
Additional file 3: of Long non-coding RNA DANCR promotes malignant phenotypes of bladder cancer cells by modulating the miR-149/MSI2 axis as a ceRNA
Creators: name: Zhan, Yonghao
name: Chen, Zhicong
name: Li, Yifan
name: He, Anbang
name: He, Shiming
name: Gong, Yanqing
name: Li, Xuesong
name: Zhou, Liqun
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: Table S3. Results of bioinformation analysis. (DOCX 17 kb)
Natural environment and human exploitation on the southern shores of Horselydown
Creators: name: Ridgeway, Victoria
Publisher: name: Archaeology Data Service
Year: 2003

description: London Archaeologist, 10 (4), 103-111
description: Work between 1997 and 2000 on five sites covering 300x200m is brought together to provide a topographic and environmental account of this area from later prehistoric exploitation of the landscape, through inundation of the area due to rising water levels, to renewed exploitation from the medieval period (when much of the study area fell within the precincts of Bermondsey Abbey) onwards into its post-medieval use for the tanning industry.
title: Philadelphia in the Fayum 2018, Sector 13, Excavation's Last Stage, Field Data 3D Model
Creators: name: Colin, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018

description: Eight obj, mtl and jpg files allowing the processing of a textured 3D model.
Huit fichiers obj, mtl et jpg permettant de faire fonctionner un modèle texturé.
description: Eight obj, mtl and jpg files allowing the processing of a textured 3D model.
Huit fichiers obj, mtl et jpg permettant de faire fonctionner un modèle texturé.
Neopodocinum mrciaki Sellnick 1968
Creators: name: Kontschán, Jenő
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Macrochelidae
Neopodocinum
Neopodocinum mrciaki

description: Neopodocinum mrciaki Sellnick, 1968
 Neopodocinum mrciaki Sellnick, 1968: 253.
 Occurrences. Mátraalmás (Ambros, 1984).
 Note. This species was collected on Apodemus flavicollis mouse species.
description: Published as part of Kontschán, Jenő, 2020, Checklist of the Hungarian species of family Macrochelidae (Acari: Mesostigmata), pp. 7-17 in Acarological Studies 2 (1) on pages 9-10
The Illusion of Randomness_ Why the Universe Was Never Probabilistic
Creators: name: Bostick, Devin
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Physics
subject: Artificial intelligence
subject: Mathematical physics
subject: Nonlinear Dynamics
subject: Metaphysics
subject: Structured Resonance
subject: CODES Framework
subject: Phase Alignment Scoring
subject: Structured Emergence

description: Main CODES Framework

Abstract

This paper dismantles the deeply held belief that randomness is a fundamental property of the universe. Across quantum physics, thermodynamics, and evolutionary biology, randomness has been treated not merely as a modeling tool but as ontological reality. This has led to a worldview rooted in uncertainty, entropy, and statistical inevitability—a paradigm that collapses under structured coherence.

Through the CODES framework (Chirality of Dynamic Emergent Systems), we show that randomness is not a law of nature—it is a measurement artifact, a byproduct of incomplete resonance detection. What appears stochastic at one scale resolves into lawful, prime-anchored coherence when observed through the correct lens. Quantum “uncertainty,” genetic “mutation,” and neural “noise” are all false categories—chaotic expressions of temporarily unresolved structure.

We present structured resonance as the primary substrate of reality, governed by prime-indexed phase alignment, chiral asymmetry, and recursive coherence scoring (PAS). From subatomic behavior to planetary motion to consciousness itself, the illusion of randomness dissolves. In its place: a lawful, nested universe breathing through coherence gradients and resonance compression.

Probability was never foundational.

Randomness was never real.

The universe tunes—it does not gamble.
Dual contribution of surface charge and protein-binding affinity to the cytotoxicity of polystyrene nanoparticles in nonphagocytic A549 cells and phagocytic THP-1 cells
Creators: name: Hwang, Sung-Hyun
name: Thielbeer, Frank
name: Jiyoung Jeong
name: Youngju Han
name: Chankeshwara, Sunay V.
name: Bradley, Mark
name: Wan-Seob Cho
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: Hematology

description: Knowledge that links the physicochemical properties of nanoparticles (NP) to their toxicity is key to evaluating and understanding mechanisms underlying toxicity and developing appropriate testing methods for NP; however, this is currently limited since only a small set of NP have been used, with typically poor control of their physical properties. In this study, eight types of polystyrene NP (PLNP) were synthesized with different functional groups, but all based on an identical core. In vitro cell-based assays were performed to determine the influence of changes in physicochemical properties, such as charge, hydrodynamic size, and protein binding potential, in relation to NP-mediated toxicity. The PLNP were incubated with nonphagocytic A549 cells or phagocytic differentiated THP-1 cells for 4 h with/without fetal bovine serum (FBS), followed by incubation for 20 h in FBS-supplemented medium with/without a washing step, to assess cell-type specificity and impact of protein corona formation. The effect of surface charge on cytotoxicity differed between A549 cells and THP-1 cells. In nonphagocytic A549 cells, the zeta potential of PLNP exhibited a negative correlation with cytotoxicity, partly due to the level of coronated protein that might affect cellular uptake. In phagocytic THP-1 cells, the zeta potential of PLNP showed a positive correlation with cytotoxicity but coronated protein levels displayed no marked association with cytotoxicity, owing to the professional uptake efficacy of phagocytic cells. The consistency of our data with THP-1 cells with the surface charge paradigm in nanotoxicology suggests that phagocytic cells are the predominant targets for lung inflammatory reactions induced by PLNP.
Archaeological excavations at 30-36 Upper Clapton Road, Hackney
Creators: name: Bagwell, Mark
name: Phillpotts, Chris
name: Jarrett, Chris D
Publisher: name: Archaeology Data Service
Year: 2003

description: London Archaeologist, 10 (5), 124-130
description: Records sixteenth- and seventeenth-century features and timber-framed building. Also notes the remains of Warwick House, pottery and clay pipe.
Additional file 1: of Stromal fibroblast activation protein alpha promotes gastric cancer progression via epithelial-mesenchymal transition through Wnt/ Î˛-catenin pathway
Creators: name: Liu, Jiuyang
name: Huang, Chaoqun
name: Peng, Chunwei
name: Xu, Fei
name: Li, Yan
name: Yutaka, Yonemura
name: Xiong, Bin
name: Yang, Xiaojun
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Table S1. Primers sequences in this study. (DOCX 15 kb)
Pro- and anti-angiogenic VEGF mRNAs in autoimmune thyroid diseases
Creators: name: Rancier, Marc
name: Zaaber, Ines
name: Stathopoulou, Maria G.
name: Chatelin, Jérôme
name: Abdelsalam Saleh
name: Héla Marmouch
name: Shamieh, Said El
name: Masson, Christine
name: Murray, Helena
name: Lamont, John
name: Fitzgerald, Peter
name: Mahjoub, Silvia
name: Said, Khaled
name: Besma Bel Haj Jrad Tensaout
name: Souhir Mestiri
name: Visvikis-Siest, Sophie
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The aim of this study was to assess the relationships between five different splice isoforms of VEGF mRNA and its plasma levels in individuals treated for autoimmune thyroid diseases (AITD); mainly Graves’ disease (GD) and Hashimoto’s thyroiditis (HT). In a population from Tunisia, levels of thyroid hormones and antibodies were quantified simultaneously with plasma VEGF and VEGF mRNA isoforms after a period of 6 months of patients’ treatment. Plasma VEGF was measured in 110 AITD patients (21 GD and 89 HT patients). VEGF isoforms (VEGF121, VEGF165, VEGF145 and VEGF189 pro-angiogenic isoforms and VEGF165b anti-angiogenic isoform) in peripheral blood mononuclear cells were quantified in 71 patients (20 GD and 51 HT patients) and 86 healthy controls. Decreased levels of VEGF189 mRNA were observed in AITD compared to controls. VEGF165 was increased in GD patients compared to controls and the VEGF165b was increased in HT patients compared to GD. We observed increased levels of VEGF165b in hypothyroid AITD patients after treatment. We have also shown that the VEGF145 isoform levels were determined by FT4 in all patients and by the thyroid status after 6 months of treatment only in HT patients. An association was observed for VEGF165 mRNA levels with anti-TPO antibodies in all patients. Finally, FT4 was associated with VEGF plasma levels but only in healthy controls. In conclusion, this descriptive study highlights the specificity of VEGF mRNA isoforms in AITD, a fact underlining the need for novel clinical trials and the development of personalised theranostic approaches.
Nothrholaspis Berlese 1918
Creators: name: Kontschán, Jenő
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Macrochelidae
Nothrholaspis

description: Nothrholaspis Berlese, 1918
Nothrholaspis Berlese, 1918: 169.
description: Published as part of Kontschán, Jenő, 2020, Checklist of the Hungarian species of family Macrochelidae (Acari: Mesostigmata), pp. 7-17 in Acarological Studies 2 (1) on page 10
Support for London's archaeological societies
Creators: name: Bunton, Vanessa
Publisher: name: Archaeology Data Service
Year: 2004

description: London Archaeologist, 10 (6), 143-147
description: Reports an English Heritage/Museum of London funded one-year project to survey the state of local archaeology societies in London and identify ways in which they could be given further useful support. Areas that support would be useful in are given as: communication; demographic diversity; fieldwork; training; and publication and archiving.
Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells
Creators: name: Antosiewicz, Anna
name: Jarmuła, Adam
name: Przybylska, Dorota
name: Grażyna Mosieniak
name: Szczepanowska, Joanna
name: Kowalkowska, Anna
name: Rode, Wojciech
name: Cieśla, Joanna
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 60506 Virology

description: Enzymes involved in thymidylate biosynthesis, thymidylate synthase (TS), and dihydrofolate reductase (DHFR) are well-known targets in cancer chemotherapy. In this study, we demonstrated for the first time, that human TS and DHFR form a strong complex in vitro and co-localize in human normal and colon cancer cell cytoplasm and nucleus. Treatment of cancer cells with methotrexate or 5-fluorouracil did not affect the distribution of either enzyme within the cells. However, 5-FU, but not MTX, lowered the presence of DHFR-TS complex in the nucleus by 2.5-fold. The results may suggest the sequestering of TS by FdUMP in the cytoplasm and thereby affecting the translocation of DHFR-TS complex to the nucleus. Providing a strong likelihood of DHFR-TS complex formation in vivo, the latter complex is a potential new drug target in cancer therapy. In this paper, known 3D structures of human TS and human DHFR, and some protozoan bifunctional DHFR-TS structures as templates, are used to build an in silico model of human DHFR–TS complex structure, consisting of one TS dimer and two DHFR monomers. This complex structure may serve as an initial 3D drug target model for prospective inhibitors targeting interfaces between the DHFR and TS enzymes.
Nothrholaspis carinatus
Creators: name: Kontschán, Jenő
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Macrochelidae
Nothrholaspis
Nothrholaspis carinatus

description: Nothrholaspis carinatus (C. L. Koch, 1839)
 Gamasus carinatus C. L. Koch 1839: 16.
 Occurrences. Budapest, Diósjenő, Nadap, Sári (Erős and Mahunka 1971a), Várgesztes (Kontschán, 2006).
description: Published as part of Kontschán, Jenő, 2020, Checklist of the Hungarian species of family Macrochelidae (Acari: Mesostigmata), pp. 7-17 in Acarological Studies 2 (1) on page 10
Additional file 1: of LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer
Creators: name: Feng, Mengyu
name: Xiong, Guangbing
name: Cao, Zhe
name: Yang, Gang
name: Zheng, Suli
name: Qiu, Jiangdong
name: You, Lei
name: Zheng, Lianfang
name: Zhang, Taiping
name: Zhao, Yupei
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology

description: Table S1. Correlations of LAT2 level in tissues and clinicopathological parameters. (DOC 44 kb)
Effect of 1-methyl-3-octyleimmidazolium chloride on the stability and activity of lysozyme: a spectroscopic and molecular dynamics studies
Creators: name: Kumari, Meena
name: Dohare, Neeraj
name: Maurya, Neha
name: Ravins Dohare
name: Patel, Rajan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: Computational Biology

description: Herein, the binding of 1-methyl-3-octylimidazolium chloride [OMIM][Cl] ionic liquid with hen egg white lysozyme (HEWL) has been studied using fluorescence, time resolved fluorescence, UV–visible and circular dichroism (CD) spectroscopy, in combination with computational study. The fluorescence results revealed that [OMIM][Cl] quenches the fluorophore of HEWL through static quenching mechanism. The calculated thermodynamic parameters show that [OMIM][Cl] bind with HEWL through hydrophobic interactions. In addition, the negative value of Gibbs energy change (∆G) indicates that the binding process was spontaneous. Furthermore, UV–vis and CD results indicate that [OMIM][Cl] induce the conformational change in HEWL and increase its enzymatic activity. Additionally, molecular docking results showed that [OMIM][Cl] binds at the active site of HEWL where both the fluorophore residues (Trp108 and Trp62) and the catalytic residues (Glu35 and Asp52) reside. Molecular dynamic simulation results show the reduction of intra-molecular hydrogen bond of HEWL when it binds with [OMIM][Cl].
Nothrholaspis montanus
Creators: name: Kontschán, Jenő
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Macrochelidae
Nothrholaspis
Nothrholaspis montanus

description: Nothrholaspis montanus (Willmann, 1951)
 Macrocheles montanus Willmann, 1951: 158.
 Occurrences. Aggtelek, Balatonszentgyörgy, Budapest, Csákvár, Diósjenő, Nadap, Sopron, Sukoró, Tátika, Törek, Vác (Erős and Mahunka, 1971a), Egyek (Kandil, 1981), Nagyvisnyó, Miskolc (Ambros, 1993), Zempléni Mts and Paks (Salmane and Kontschán, 2005), Mecsek, Bátaapáti (Salmane and Kontschán, 2006), Villányi Mts (Kontschán, 2005), Várgesztes, Budapest, Szigetbecse, Nagyrécse (Kontschán, 2006).
description: Published as part of Kontschán, Jenő, 2020, Checklist of the Hungarian species of family Macrochelidae (Acari: Mesostigmata), pp. 7-17 in Acarological Studies 2 (1) on page 10
title: 03_0966
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
title: Relation between peripheral to central pulmonary artery diameter ratio with chronic obstructive pulmonary disease severity
Creators: name: ILYAS, Vininta Fazharyasti
Publisher: name: European Society of Thoracic Imaging
Year: 2019
Subjects: subject: Chronic obstructive airways disease
subject: Contrast agent-intravenous
subject: CT-High Resolution
subject: CT
subject: Thorax
subject: Pulmonary vessels
subject: Lung

description: Purpose Methods Materials Results Conclusion References Personal Information
description: Purpose: Chronic Obstructive Pulmonary Disease (COPD) is a pulmonary disease that has an extrapulmonary effect that can worsen the patient's condition, and is one of the major causes of morbidity and mortality in the world, but is now less widely recognized...
title: Lung cancer detected through CT surveillance of incidental lung nodules
Creators: name: Manos, Daria
Publisher: name: European Society of Thoracic Imaging
Year: 2019
Subjects: subject: Quality assurance
subject: Cancer
subject: Health policy and practice
subject: Decision analysis
subject: Audit and standards
subject: CT
subject: Thorax
subject: Oncology
subject: Lung

description: Purpose Methods Materials Results Conclusion References Personal Information
description: Purpose: Lung nodules are found in up to 50% of adults and are often an incidental asymptomatic finding (1,2). For many nodules, several well-established guidelines recommend surveillance CT to exclude malignancy (3,4).However, the risk of lung cancer in...
New insights into Legionella pneumophila biofilm regulation by c-di-GMP signaling
Creators: name: Pécastaings, Sophie
name: Allombert, Julie
name: Lajoie, Barbora
name: Doublet, Patricia
name: Roques, Christine
name: Vianney, Anne
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: The waterborne pathogen Legionella pneumophila grows as a biofilm, freely or inside amoebae. Cyclic-di-GMP (c-di-GMP), a bacterial second messenger frequently implicated in biofilm formation, is synthesized and degraded by diguanylate cyclases (DGCs) and phosphodiesterases (PDEs), respectively. To characterize the c-di-GMP-metabolizing enzymes involved in L. pneumophila biofilm regulation, the consequences on biofilm formation and the c-di-GMP concentration of each corresponding gene inactivation were assessed in the Lens strain. The results showed that one DGC and two PDEs enhance different aspects of biofilm formation, while two proteins with dual activity (DGC/PDE) inhibit biofilm growth. Surprisingly, only two mutants exhibited a change in global c-di-GMP concentration. This study highlights that specific c-di-GMP pathways control L. pneumophila biofilm formation, most likely via temporary and/or local modulation of c-di-GMP concentration. Furthermore, Lpl1054 DGC is required to enable the formation a dense biofilm in response to nitric oxide, a signal for biofilm dispersion in many other species.
title: Testing of different scoring methods of lung HRCT in patients with scleroderma
Creators: name: Vanasek, Jiri
Publisher: name: European Society of Thoracic Imaging
Year: 2019
Subjects: subject: Lung
subject: CT-High Resolution
subject: Comparative studies
subject: Connective tissue disorders

description: Purpose Methods Materials Results Conclusion References Personal Information
description: Purpose: The aim of this pilot study was to assess accurancy of three different types of scoring systems of HRCT of the lung in patiens with systemic sclerosis according to decline of lung functional tests. We tried to divide patients to limited disease...
"Conversando con Cortázar"
Creators: name: Indeterminado
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Julio Cortázar

description: Anuncio de la proyección de la película "Conversando con Cortázar" de Eric Van Zeulen, presentada por Saúl Yurkievich.
description: Source: Num.Ref. : JC-DY-CAR-04.066
description: Source: Localización del archivo: Centre de Recherches Latino-Américaines (CRLA–Archivos, ITEM UMR8132). MSHS - Bât. A5, 1er étage 5 rue Théodore Lefebvre - TSA21103. 86073 Poitiers cedex 9.
title: Long-term outcome after surgical treatment for part-solid lung cancer less than 3 cm: single institutional experience
Creators: name: Kim, Tae Hoon
Publisher: name: European Society of Thoracic Imaging
Year: 2019
Subjects: subject: Cancer
subject: Surgery
subject: CT
subject: Lung

description: Purpose Methods Materials Results Conclusion References Personal Information
description: Purpose: Ground glass opacity nodule (GGN) with or without part-solid portion is a common finding of early lung adenocarcinoma. There have been many studies on GGNs, but the extent and appropriate timing of surgical resection and lymphadenectomy are...
title: Thoracic CT Findings Predictive of Treatment in Drowning
Creators: name: Tsuchiya, Nanae
Publisher: name: European Society of Thoracic Imaging
Year: 2019
Subjects: subject: CT
subject: Lung
subject: Emergency
subject: Decision analysis
subject: Outcomes

description: Purpose Methods Materials Results Conclusion References Personal Information
description: Purpose: Drowning is the process of experiencing respiratory impairment from submersion/immersion in liquid (1). To predict prognosis and guide interventions, the Szpilman clinical classification system of six grades is useful (2). In clinical practice, an...
title: Diagnostic outcome and safety of CT-guided core needle biopsy for mediastinal mass: A Systematic review and meta-analysis
Creators: name: Lee, Han Na
Publisher: name: European Society of Thoracic Imaging
Year: 2019
Subjects: subject: Biopsy
subject: CT
subject: Thorax
subject: Neoplasia

description: Purpose Methods Materials Results Conclusion References Personal Information
description: Purpose: Mediastinal masses include a wide spectrum of malignant and benign lesions and accurate pathologic diagnosis is mandatory for determining appropriate treatment strategies in patients with mediastinal masses CT-guided procedure is widely used for the...
title: Diagnostic accuracy of CT-guided core biopsy of thin-walled cavitary pulmonary lesions
Creators: name: Shin, Kyung Eun
Publisher: name: European Society of Thoracic Imaging
Year: 2019
Subjects: subject: Pathology
subject: Cavitation
subject: Cancer
subject: Complications
subject: Biopsy
subject: CT
subject: Oncology
subject: Lung

description: Purpose Methods Materials Results Conclusion References Personal Information
description: Purpose: To evaluate the accuracy of CT-guided percutaneous core biopsy of the thin-walled cavitary...
title: Phantom Experimental study on Radiation dose to Doctors using an ambu-bag during head CT scan: Comparison study with non-Pb apron
Creators: name: SUNG, DONGWOOK
Publisher: name: European Society of Thoracic Imaging
Year: 2019
Subjects: subject: Dosimetric comparison
subject: Radiation safety
subject: CT
subject: Radioprotection / Radiation dose

description: Purpose Methods Materials Results Conclusion References Personal Information
description: Purpose: Recently a letter to IAEA from Korea 1) I'm intern working on one of university hospital in South Korea 2) Often have an ambu-bag on CT in unconscious patients 3) I do not know how much radiation exposure I get 4) But I can't find any reports about...
Subtropical demersal fish communities on soft sediments in the KwaZulu-Natal Bight, South Africa
Creators: name: ST Fennessy
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The project entitled Ecosystem Processes in the KwaZulu-Natal Bight, part of the African Coelacanth Ecosystem Programme (ACEP), enabled the description of demersal fish communities over soft sediments, including from some areas that have rarely been explored in the subtropical waters of the east coast of South Africa. A total of 165 fish taxa from 78 families were caught, and were dominated by the Sparidae (five species), Triglidae (four species), Acropomatidae (three species), Macrouridae (eight species), Chlorophthalmidae (one species), Paralichthyidae (three species) and Sciaenidae (six species), which together contributed 75% and almost 60% to numbers and weight, respectively. The most ubiquitous species were Chlorophthalmus punctatus and Pagellus natalensis. Species composition was structured mainly by depth, and proximity to the Thukela River, the latter being particularly influential on the adjacent Thukela Bank that harbours a unique community. There are close affinities between KZN Bight soft-sediment fish communities and those off Western Australia, and particularly with communities from East Africa. The unique nature of fish communities off the Thukela River is part-motivation towards the establishment of a large marine protected area in the northern part of the KZN Bight, which is increasingly the focus of disruptions such as impoundments and mining.
What can we learn from the (digital) Commons?: Ästhetische Praxen des Lernens und Verlernens
Creators: name: Sollfrank, Cornelia
Publisher: name: Zenodo
Year: 2019
Subjects: Commons
Creating Commons
Bildung
Vermittlung
Kunstinstitution
Radikale Pädagogik
Feministische Pädagogik

description: Edukatorische Formate und Projekte im Kunstfeld gehören inzwischen – jedenfalls seit dem "educational turn" – zur alltäglichen Praxis. Kunstinstitutionen bieten Workshops an oder stellen Ressourcen bereit für vielfältige Formate: Colleges, Akademien, Free Schools. Damit stellen sie Lernsituationen her, in denen spekuliert, reflektiert, aktualisiert und produziert werden kann – unabhängig von verordneten Notwendigkeiten, entlang selbstbestimmter Dringlichkeiten. Als Teil kuratorischer Praxis ausführlich theoretisiert und problematisiert stehen diese Aktivitäten für einen "Shift vom Ausstellungmachen zur Produktion von Wissen" und haben die ehemals eher stiefmütterlich behandelten Fragen von Bildung als (Teil-)Aufgabe der Kunst dem Bereich der klassischen Vermittlung entrissen und mit der Symbolkraft neuer diskursiver Macht ausgestattet. Darauf reagierte die Kunstvermittlung mit einem eigenen Shift, einem "educational turn in education", der darin besteht, vermehrt radikale und kritische Bildungsansätze aufzugreifen und weiterzuentwickeln – in eine kritische Praxis der Vermittlung.
description: + ID: 571635 + PeerReviewed: Peer Reviewed
Archaeological investigations at North Street/ George Street, Barking
Creators: name: Hawkins, Duncan
name: Meddens, Frank M
name: Moore, Peter
name: Farid, Shahina
name: Truckle, Nick
Publisher: name: Archaeology Data Service
Year: 2004

description: London Archaeologist, 10 (6), 148-153
description: In late 1996 and early 1997 excavations revealed a possible property boundary running east/west across the site at a right angle to North Street. The association of this feature with low-status domestic occupation and its location 280m north-east of the probable precinct of the medieval abbey may indicate the presence of a secular settlement contemporary with the AS abbey.
Species composition, abundance and biomass of microphytoplankton in the KwaZulu-Natal Bight on the east coast of South Africa
Creators: name: JS Van Der Molen
name: UM Scharler
name: D Muir
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Nearshore marine environments are influenced by an array of variables that can either be land-derived or of marine origin, and nearshore phytoplankton communities may differ in their taxonomic composition and biomass in response to such variables. The KwaZulu-Natal Bight (hereafter referred to as ‘the bight’) is an oligo-mesotrophic, nearshore oceanic environment, that is influenced by both terrestrial run-off and upwelling. A microphytoplankton survey of the bight conducted over several stations and depths and two seasons was conducted in order to ascertain species composition, abundance and biomass. Microphytoplankton abundance was generally low (a maximum of 180 000 cells l–1 was recorded) but differed considerably between sites and seasons. A total of 99 taxa of mainly Bacillariophyceae and some Dinophyceae, Prymnesiophyceae and Cyanophyceae were identified in the present study. In the central bight, higher abundance and biomass were measured in February (wet season), which may be a possible consequence of terrestrial nutrient inputs. In the northern and southern bight we measured higher abundance and biomass in August (dry season). Upwelling was not detected during the study, but an influence of terrestrial nutrient sources was detected at the coastal stations. Turbid conditions were specific to the site near the Thukela River mouth and possibly influenced abundance, biomass and species composition at this site. Historic data on microphytoplankton composition are scarce, but comparisons with surveys from the 1960s reveal that around 60% of the common diatoms recorded then also occurred in the present study. Small taxa [20–200 µm] dominated the microphytoplankton community. Community composition was fairly uniform throughout the bight in both seasons, dominated in general by Chaetoceros species, and on occasion co-dominated by Thalassionema nitzschioides and Dactyliosolen fragilissimus.
Cheap and cheerful: socially inclusive archaeology in Hackney and Lambeth
Creators: name: Smith, Lesley
Publisher: name: Archaeology Data Service
Year: 2004

description: London Archaeologist, 10 (6), 162-166
description: Chronicles a project designed to help participants claim their own history and ownership of their own environment and presented in the form of workshops targeted at various constituencies (children, over-50s etc).