cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Econometric models of financial risks
Creators: name: Castelli, Francesca <1982>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: SECS-P/05 Econometria

description: The goal of this dissertation is to use statistical tools to analyze specific financial risks that have played dominant roles in the US financial crisis of 2008-2009.
The first risk relates to the level of aggregate stress in the financial markets. I estimate the impact of financial stress on economic activity and monetary policy using structural VAR analysis. 
The second set of risks concerns the US housing market. There are in fact two prominent risks associated with a US mortgage, as borrowers can both prepay or default on a mortgage. I test the existence of unobservable heterogeneity in the borrower's decision to default or prepay on his mortgage by estimating a multinomial logit model with borrower-specific random coefficients.
Optimal control as a graphical model inference problem
Creators: name: Kappen, B.
name: Gomez, V.
name: Opper, M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Optimization and Control (math.OC)
subject: Systems and Control (eess.SY)
subject: FOS: Mathematics
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: F.1.2; G.3; I.2.8

description: We reformulate a class of non-linear stochastic optimal control problems introduced by Todorov (2007) as a Kullback-Leibler (KL) minimization problem. As a result, the optimal control computation reduces to an inference computation and approximate inference methods can be applied to efficiently compute approximate optimal controls. We show how this KL control theory contains the path integral control method as a special case. We provide an example of a block stacking task and a multi-agent cooperative game where we demonstrate how approximate inference can be successfully applied to instances that are too complex for exact computation. We discuss the relation of the KL control approach to other inference approaches to control.
description: 26 pages, 12 Figures; Machine Learning Journal (2012)
Spectral-Element and Adjoint 3D Full-Wave Tomography for the Lithosphere of Central Italy
Creators: name: Magnoni, Federica <1982>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: GEO/10 Geofisica della terra solida

description: The primary objective of this thesis is to obtain a better understanding of the 3D velocity structure of the lithosphere in central Italy.
To this end, I adopted the Spectral-Element Method to perform accurate numerical simulations of the complex wavefields generated by the 2009 Mw 6.3 L’Aquila event and by its foreshocks and aftershocks together with some additional events within our target region. 
For the mainshock, the source was represented by a finite fault and different models for central Italy, both 1D and 3D, were tested.
Surface topography, attenuation and Moho discontinuity were also accounted for. Three-component synthetic waveforms were compared to the corresponding recorded data.
The results of these analyses show that 3D models, including all the known structural heterogeneities in the region, are essential to accurately reproduce waveform propagation. They allow to capture features of the seismograms, mainly related to topography or to low wavespeed areas, and, combined with a finite fault model, result into a favorable match between data and synthetics for frequencies up to ~0.5 Hz. We also obtained peak ground velocity maps, that provide valuable information for seismic hazard assessment. The remaining differences between data and synthetics led us to take advantage of SEM combined with an adjoint method to iteratively improve the available 3D structure model for central Italy. A total of 63 events and 52 stations in the region were considered. We performed five iterations of the tomographic inversion, by calculating the misfit function gradient - necessary for the model update - from adjoint sensitivity kernels, constructed using only two simulations for each event. Our last updated model features a reduced traveltime misfit function and improved agreement between data and synthetics, although further iterations, as well as refined source solutions, are necessary to obtain a new reference 3D model for central Italy tomography.
Area spectrum of the D-dimensional de Sitter spacetime
Creators: name: Lopez-Ortega, A.
Publisher: name: arXiv
Year: 2009
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The determination of the quantum area spectrum of a black hole horizon by means of its asymptotic quasinormal frequencies has been explored recently. We believe that for D-dimensional de Sitter horizon we must study if the idea works. Thus taking into account the local description of the thermodynamics of horizons proposed by Padmanabhan and the results of Hod, Kunstatter, and Maggiore we study the area spectrum of the D-dimensional de Sitter horizon.
description: 6 pages, accepted for publication in Physics Letters B
Participation and autonomy in the first 10 months after diagnosis of ALS: a longitudinal study
Creators: name: Reenen, Esther T. Kruitwagen-Van
name: Scholten, Eline W. M.
name: van Groenestijn, Annerieke
name: Van Den Berg, Leonard H.
name: Post, Marcel W. M.
name: Visser-Meily, Johanna
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Introduction: More insight is needed into participation in daily activities and autonomy among patients with amyotrophic lateral sclerosis (ALS). Aims of this study were (1) to describe the course of participation restrictions and autonomy in participation during the first 10 months after diagnosis; (2) to study the influence of the rate of ALS progression on the course of participation. Methods: Secondary analysis of data from the longitudinal multicenter FACTS-2-ALS study. Self-report questionnaires were administered at inclusion (T0; n = 71), at 4 months (T1), 7 months (T2), 10 months (T3) after inclusion. Median duration of follow-up was 10.0 months. Participation restrictions were assessed using the sum of the Mobility Range and Social Behavior subscales of the Sickness Impact profile-68 (SIPSOC). Autonomy in participation was assessed using the Impact on Participation and Autonomy (IPA) Questionnaire. Fast disease progression was defined as an increase of 1.1 points per month or more on the ALS Functional Rating Scale. Results: Patients reported participation restrictions in all subscales while having mild physical limitations. There was a decrease of participation over time (restrictions and autonomy). This decrease was greatest in patients with fast disease progression. Disease progression negatively influenced movement-related participation more than social interaction domains. Rate of disease progression was more strongly related to SIPSOC scores compared to IPA scores. Discussion: Preserving participation may be an important determinant of quality of care for patients with ALS. Rate of progression of the disease should be taken into account as it was found to be significantly associated with the level of participation.
K* resonance effects on direct CP violation in B -> pi pi K
Creators: name: Leitner, O.
name: Dedonder, J. -P.
name: Loiseau, B.
name: Kaminski, R.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Charged and neutral B decays into two charged pions and a charged or a neutral kaon are analyzed within the QCD factorization scheme where final state interactions before and after hadronization are included. The K*(892) and K*(1430) resonance effects are taken into account using the presently known pion-Kaon strange vector and scalar form factors. The weak decay amplitudes, which are calculated at leading power in Lambda_QCD/m_b and at the next-to-leading order in the strong coupling constant, include the hard scattering and annihilation contributions. The end point divergences of these weak final state interactions are controlled by two complex parameters determined through a fit to the available effective mass and helicity angle distribution, CP asymmetry and K*(892) branching ratio data. The predicted K*(1430) branching ratios and the calculated direct CP violation asymmetries are compared to the Belle and BABAR Collaboration data.
description: Comments: 22 pages, 2 figures and 3 tables. In this new version, the results are unchanged, but, the last paragraph of the Section "RESULTS AND SUMMARY" (now called "RESULTS AND DISCUSSION") has been replaced by a new Section "SUMMARY AND OUTLOOK". To appear in Physical Review D
title: Kommentierung zu Art. 2a Abs. 1-2 und 4-5 GwG
Creators: name: Adank, Florian
Publisher: name: Fachinformationsdienst für internationale und interdisziplinäre Rechtsforschung
Year: 2025
Subjects: subject: 340

description: Geldwäschereigesetz (GwG): Onlinekommentar
A connection between the Ghirlanda--Guerra identities and ultrametricity
Creators: name: Panchenko, Dmitry
Publisher: name: arXiv
Year: 2008
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 60K35, 82B44 (Primary)

description: We consider a symmetric positive definite weakly exchangeable infinite random matrix and show that, under the technical condition that its elements take a finite number of values, the Ghirlanda--Guerra identities imply ultrametricity.
description: Published in at http://dx.doi.org/10.1214/09-AOP484 the Annals of Probability (http://www.imstat.org/aop/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Social aspects of collision avoidance: A detailed analysis of two-person groups and individual pedestrians
Creators: name: Gregorj, Adrien
name: Yücel, Zeynep
name: Zanlungo, Francesco
name: Feliciani, Claudio
name: Kanda, Takayuki
Publisher: name: arXiv
Year: 2023
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: Pedestrian groups are commonly found in crowds but research on their social aspects is comparatively lacking. To fill that void in literature, we study the dynamics of collision avoidance between pedestrian groups (in particular dyads) and individual pedestrians in an ecological environment, focusing in particular on (i) how such avoidance depends on the group's social relation (e.g. colleagues, couples, friends or families) and (ii) its intensity of social interaction (indicated by conversation, gaze exchange, gestures etc). By analyzing relative collision avoidance in the ``center of mass'' frame, we were able to quantify how much groups and individuals avoid each other with respect to the aforementioned properties of the group. A mathematical representation using a potential energy function is proposed to model avoidance and it is shown to provide a fair approximation to the empirical observations. We also studied the probability that the individuals disrupt the group by ``passing through it'' (termed as intrusion). We analyzed the dependence of the parameters of the avoidance model and of the probability of intrusion on groups' social relation and intensity of interaction. We confirmed that the stronger social bonding or interaction intensity is, the more prominent collision avoidance turns out. We also confirmed that the probability of intrusion is a decreasing function of interaction intensity and strength of social bonding. Our results suggest that such variability should be accounted for in models and crowd management in general. Namely, public spaces with strongly bonded groups (e.g. a family-oriented amusement park) may require a different approach compared to public spaces with loosely bonded groups (e.g. a business-oriented trade fair).
description: 25 pages, 15 figures, 3 tables
Juvenile amyotrophic lateral sclerosis with complex phenotypes associated with novel SYNE1 mutations
Creators: name: Naruse, Hiroya
name: Ishiura, Hiroyuki
name: Mitsui, Jun
name: Takahashi, Yuji
name: Matsukawa, Takashi
name: Toda, Tatsushi
name: Tsuji, Shoji
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Mutations in SYNE1 have been originally described to cause a slowly progressive, pure cerebellar ataxia (spinocerebellar ataxia, autosomal-recessive 8; SCAR8). Notably, recent studies revealed that affected patients with SYNE1-associated ataxia can present with complex phenotypes rather than pure cerebellar ataxia, including motor neuron and brainstem dysfunctions. We herein report a Japanese patient diagnosed with juvenile amyotrophic lateral sclerosis (ALS) with a complex phenotype, who carried compound heterozygous pathogenic variants in SYNE1. Of the variants, one was a novel frameshift variant and the other was a nonsense variant previously reported as pathogenic for SCAR8. The patient showed an early age at onset with a relatively slow but progressive course of ALS, accompanied by cognitive decline. Our findings suggest that the clinical spectrum of patients carrying pathogenic SYNE1 variants is broader than expected, and SYNE1 variants should be considered in patients diagnosed with juvenile ALS, even without prominent cerebellar ataxia.
Welcome to ESMARConf2022
Creators: name: Haddaway, Neal
Publisher: name: Zenodo
Year: 2022
Subjects: ESMARConf2022
evidence synthesis
meta-analysis
RStats

description: This presentation opens the official ESMARConf2022 programme. Learn about ESMARConf's objectives and values, details from this year's funder, Code for Science & Society, and more about our Accessibility Policy and Code of Conduct.
Hardy spaces of the conjugate Beltrami equation
Creators: name: Baratchart, Laurent
name: Leblond, Juliette
name: Rigat, Stéphane
name: Russ, Emmanuel
Publisher: name: arXiv
Year: 2009
Subjects: subject: Complex Variables (math.CV)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We study Hardy spaces of solutions to the conjugate Beltrami equation with Lipschitz coefficient on Dini-smooth simply connected planar domains, in the range of exponents $1
title: GSICS quarterly. Volume 3, number 1 (2009)
Creators: name: Global Space-Based Inter-Calibration System Coordination Center,
Publisher: name: U.S. Department of Commerce, National Oceanic and Atmospheric Administration, National Environmental Satellite, Data, and Information Service, Center for Satellite Applications and Research
Year: 2009
Subjects: subject: Satellite meteorology
subject: Global Observing System (Meteorology)

description: GSICS Quarterly is a newsletter designed to communicate GSICS activities to all GSICS members and partners, as well as to satellite data users and policy makers
Competing Topological Orders in the nu=12/5 Quantum Hall State
Creators: name: Bonderson, Parsa
name: Feiguin, Adrian E.
name: Moller, Gunnar
name: Slingerland, J. K.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We provide numerical evidence that a p_{x}-i p_{y} paired Bonderson--Slingerland (BS) non-Abelian hierarchy state is a strong candidate for the observed nu=12/5 quantum Hall plateau. We confirm the existence of a gapped incompressible nu = 12/5 quantum Hall state with shift S=2 on the sphere, matching that of the BS state. The exact ground state of the Coulomb interaction at S=2 is shown to have large overlap with the BS trial wave function. Larger overlaps are obtained with BS-type wave functions that are hierarchical descendants of general p_{x}-i p_{y} weakly-paired states at nu=5/2. We perform a finite size scaling analysis of the ground state energies for nu=12/5 states at shifts corresponding to the BS (S=2) and 3-clustered Read-Rezayi (S=-2) universality classes. This analysis reveals very tight competition between these two non-Abelian topological orders.
description: 5 pages, 2 figures; v2: minor corrections; v3: new title, revised exposition, inclusion of neutral gap and finite well-width results; v4: minor corrections
Additional file 1 of Differential in vitro effects of targeted therapeutics in primary human liver cancer: importance for combined liver cancer
Creators: name: Malik, Ihtzaz Ahmed
name: Rajput, Mansi
name: Werner, Rieke
name: Fey, Dorothea
name: Salehzadeh, Niloofar
name: von Arnim, Christine A. F.
name: Wilting, Jörg
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 1: Suppl. Figure 1. Uncropped Western-blot images of 25µM MK-2206-treated HUH28 and RBE and SSP25 with specific antibodies against total AKT and p-AKT, mTOR and p-mTOR, ERK1/2 and p-ERK1/2. α-Tubulin was used as loading control. Note: Images correspond to figure 1B. Suppl. Figure 2. Uncropped Western-blot images of 25µM MK-2206-treated EGI1 and CCC5 with specific antibodies against total AKT and p-AKT, mTOR and p-mTOR, ERK1/2 and p-ERK1/2. α-Tubulin was used as loading control. Note: Images correspond to figure 2B. Suppl. Figure 3. Uncropped Western-blot images of 25µM MK-2206-treated HEP3B and HUH7 with specific antibodies against total AKT and p-AKT, mTOR and p-mTOR, ERK1/2 and p-ERK1/2. α-Tubulin was used as loading control. Note: Images correspond to figure 3B.
Morphological correlations to an electrical resistance barrier in the eye of the locust Schistocerca gregaria
Creators: name: Simpson, William Wilson
Publisher: name: University of British Columbia
Year: 2010

description: The basic morphology and ultrastructure of the compound eye of the locust Schistocerca gregaria, has been investigated. Morphologically the locust eye was found to be similar to that observed by Horridge (1966) and to those of other insects such as the honey-bee drone, Apis mellifera (Perrelet, 1970). Ultrastructurally, this invertebrate sense organ suggests that there is little extracellular space between the cells of an ommatidium within the retina, as shown by the presence of differentiated plasma membranes in the form of narrow gap junctions. This type of membrane differentiation may be related to the demonstrated existence of a retinal resistance barrier (Shaw, 1975). This suggests that the physiologically demonstrated barrier may require only minor structural alterations within the retina. It is suggested that the barrier may be the same in other invertebrates.
Espaços públicos responsivos e arte digital: informação e transformação social
Creators: name: Santos, Andre Pinto
name: Almeida, Marcela Alves
Publisher: name: Labfront/UEMG
Year: 2023

description: Dentro do panorama das cidades inteligentes há o uso massivo de tecnologias voltadas para a geração de dados que alimentam sistemas fechados e sociotécnicos que se tornam inacessíveis ou ilegíveis para a população. Em contraponto, o conceito de espaços públicos responsivos busca ativar a cidade e convidar o cidadão a usufruir do espaço público, usando meios digitais e a interação em tempo real ou não. Neste contexto a tecnologia é um meio para criar espaços agradáveis, interativos, convidativos e informativos. Deste modo, o objetivo deste trabalho é analisar através de revisão bibliográfica como as artes digitais inseridas no espaço público podem ser utilizadas como meios de comunicar dados tornando-os responsivos e deste modo, visibilizar pautas importantes obre a cidade e seu lugar de convivência, criando formas de empoderamento social através da arte.
SN 2009kf : a UV bright type IIP supernova discovered with Pan-STARRS 1 and GALEX
Creators: name: Botticella, M. T.
name: Trundle, C.
name: Pastorello, A.
name: Rodney, S.
name: Rest, A.
name: Gezari, S.
name: Smartt, S. J.
name: Narayan, G.
name: Huber, M. E.
name: Tonry, J. L.
name: Young, D.
name: Smith, K.
name: Bresolin, F.
name: Valenti, S.
name: Kotak, R.
name: Mattila, S.
name: Kankare, E.
name: Wood-Vasey, W. M.
name: Riess, A.
name: Neill, J. D.
name: Forster, K.
name: Martin, D. C.
name: Stubbs, C. W.
name: Burgett, W. S.
name: Chambers, K. C.
name: Dombeck, T.
name: Flewelling, H.
name: Grav, T.
name: Heasley, J. N.
name: Hodapp, K. W.
name: Kaiser, N.
name: Kudritzki, R.
name: Luppino, G.
name: Lupton, R. H.
name: Magnier, E. A.
name: Monet, D. G.
name: Morgan, J. S.
name: Onaka, P. M.
name: Price, P. A.
name: Rhoads, P. H.
name: Siegmund, W. A.
name: Sweeney, W. E.
name: Wainscoat, R. J.
name: Waters, C.
name: Waterson, M. F.
name: Wynn-Williams, C. G.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present photometric and spectroscopic observations of a luminous type IIP Supernova 2009kf discovered by the Pan-STARRS 1 (PS1) survey and detected also by GALEX. The SN shows a plateau in its optical and bolometric light curves, lasting approximately 70 days in the rest frame, with absolute magnitude of M_V = -18.4 mag. The P-Cygni profiles of hydrogen indicate expansion velocities of 9000km/s at 61 days after discovery which is extremely high for a type IIP SN. SN 2009kf is also remarkably bright in the near-ultraviolet (NUV) and shows a slow evolution 10-20 days after optical discovery. The NUV and optical luminosity at these epochs can be modelled with a black-body with a hot effective temperature (T ~16,000 K) and a large radius (R ~1x10^{15} cm). The bright bolometric and NUV luminosity, the lightcurve peak and plateau duration, the high velocities and temperatures suggest that 2009kf is a type IIP SN powered by a larger than normal explosion energy. Recently discovered high-z SNe (0.7 < z < 2.3) have been assumed to be IIn SNe, with the bright UV luminosities due to the interaction of SN ejecta with a dense circumstellar medium (CSM). UV bright SNe similar to SN 2009kf could also account for these high-z events, and its absolute magnitude M_NUV = -21.5 +/- 0.5 mag suggests such SNe could be discovered out to z ~2.5 in the PS1 survey.
description: Accepted for publication in APJL
Antimicrobial activity of peach and grapevine defensins
Creators: name: Nanni, Valentina <1984>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: AGR/12 Patologia vegetale

description: Antimicrobial peptides (AMPs) are an important component of the innate immune system of the plants. Plant defensins are a large family of antimicrobial peptides with several interesting features, such as small dimension, high stability and broad spectrum of action. The discovery of new molecules and the study of their mechanism of action allow to consider them attractive for biotechnological applications.
In this PhD thesis a defensin from Prunus persica (PpDFN1) and four novel DEFensin Like (DEFL) peptides from Vitis vinifera have been studied. In order to characterize the antimicrobial activity of these molecules, the recombinant mature peptides have been expressed in Escherichia coli and purified to homogeneity by chromatography techniques.
PpDFN1 is able to inhibit the growth of B. cinerea, P. expansum and M. laxa with different intensity. The recombinant peptide is capable of membrane permeabilization as demonstrated by SYTOX green fluorescence uptake in treated mycelia. Its interaction with membranes containing sphingolipid species has been shown by artificial lipid monolayers. Furthermore, PpDFN1 displays stronger interaction with monolayers composed by lipids extracted from sensitive fungi with the highest interaction against P. expansum, the most sensitive fungi to PpDFN1 action. 
DEFL 13, a defensin from grapevine, resulted the strongest antibotrytis peptides. It is electrostatically attracted to the fungal membranes as shown by the antagonist effect of the cations and is able to membrane permeabilization in B. cinerea hyphae. DEFL 13 is internalized in fungal cells and leads to fungal death by activation of some signaling pathways as demonstrated by screening of a mutant collection of B. cinerea
Proof of projective Lichnerowicz conjecture for pseudo-Riemannian metrics with degree of mobility greater than two
Creators: name: Kiosak, Volodymyr
name: Matveev, Vladimir S.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Differential Geometry (math.DG)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 53A20, 53B10, 53B20, 53B30, 53B50, 53C21, 53C50, 53C80, 37J30

description: We prove an important partial case of the pseudo-Riemannian version of the projective Lichnerowicz conjecture stating that a complete manifold admitting an essential group of projective transformations is the round sphere (up to a finite cover).
description: 32 pages, one .eps figure. The version v1 has a misprint in Theorem 1: I forgot to write the assumption that the degree of mobility is greater than two. The versions v3, v4 have only cosmetic changes wrt v2
Prevalence of pain in amyotrophic lateral sclerosis: a systematic review and meta-analysis
Creators: name: Hurwitz, Naomi
name: Radakovic, Ratko
name: Boyce, Eleanor
name: Peryer, Guy
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Objectives: Physical pain is a known symptom in amyotrophic lateral sclerosis (ALS), but no systematically derived prevalence estimate is available. The aim of this study was to determine the pooled prevalence of pain in ALS, relative to its method of measurement and pain characteristics. Methods: A systematic search across multiple databases was conducted on January 16, 2020. Random-effects meta-analyses of single proportions were performed on prevalence data. Heterogeneity was determined using the I2 statistic. Where available, pain location, intensity, and type or source were compared. Results: 2552 articles were identified. Twenty-one eligible studies were included. All studies used observational designs (14 cross-sectional, 6 cohort, 1 case-control). Pooled prevalence of pain in ALS across all studies was 60% (95% CI = 50–69%), with a high degree of heterogeneity (I2 = 94%, p < .001). Studies that used only validated measures had lower heterogeneity (I2 = 82%, p = 0.002), compared to those that used tailored measures, or tailored supplemented with validated measures (I2 = 90%, p I2 = 83%, p N = 9), the most commonly reported pain location was the upper limbs including shoulders/extremities (41.5%). A further study subset (N = 7) showed moderate-severe intensity pain was most frequently reported. Type of pain was commonly related to cramp or spasm. Conclusions: Experiencing physical pain in ALS occurs with high prevalence. Deriving consensus on which specific tools should be used to assess, monitor and compare symptoms of pain in this population will reduce current heterogeneity in approaches and increase the likelihood of ameliorating distressing experiences more effectively.
Investigation of controlled salinity waterflooding mechanisms in carbonate rocks using micro-computed tomography
Creators: name: Selem, Ahmed
Publisher: name: Imperial College London
Year: 2023

description: Low salinity waterflooding can improve oil recovery from reservoir rocks by changing the wettability from oil-wet towards more water-wet conditions. To investigate the underlying mechanisms of this process, high-resolution X-ray imaging combined with high-pressure and temperature flow apparatus were used to compare secondary and tertiary low salinity waterflooding in carbonate rock samples. Two different crude oil, brine, and rock (COBR) systems were examined. In the experiments on Estaillades quarry limestone, low salinity waterflooding caused a decrease in average contact angle to 102°, indicating a wettability change from oil-wet to more water-wet conditions. The shift in mean curvature and capillary pressure to positive values further supported this change. Micro-droplets of water were observed within the oil phase and oil layers detached from the rock surface after tertiary low salinity waterflooding. Similar mechanisms were observed in the secondary low salinity waterflooding experiment, with a faster pace and recovery of 85% of the oil initially in place in the resolved porosity. Pore and throat occupancy analysis revealed a redistribution of fluids as more brine was injected. In the experiments on a reservoir limestone with another crude oil, emulsification of oil was observed with the injection of reduced salinity brine. An intermediate phase that appeared to be a mixture of oil and brine was imaged when low salinity brine was injected, and more emulsification was observed when only low-salinity brine was injected initially. The formation of this intermediate phase is the mechanism by which the oil is mobilized. Overall, the analysis captured the in situ mechanisms and processes associated with the low salinity effect and ultimate increase in oil recovery. The study found that improved recovery was associated with a change in contact angle and pore occupancy, as well as the formation of micro-dispersions of water in oil and the emulsification of oil.
The coupling between electron transfer and Protein/Solvent Dynamics in Photosynthetic Reaction Centers: Spectroscopic Studies in Amorphous Matrices
Creators: name: Malferrari, Marco <1984>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: BIO/10 Biochimica

description: We investigated at the molecular level protein/solvent interactions and their relevance in protein function through the use of amorphous matrices at room temperature. As a model protein, we used the bacterial photosynthetic reaction center (RC) of Rhodobacter sphaeroides, a pigment protein complex which catalyzes the light-induced charge separation initiating the conversion of solar into chemical energy. The thermal fluctuations of the RC and its dielectric conformational relaxation following photoexcitation have been probed by analyzing the recombination kinetics of the primary charge-separated (P+QA-) state, using time resolved optical and EPR spectroscopies. We have shown that the RC dynamics coupled to this electron transfer process can be progressively inhibited at room temperature by decreasing the water content of RC films or of RC-trehalose glassy matrices. Extensive dehydration of the amorphous matrices inhibits RC relaxation and interconversion among conformational substates to an extent comparable to that attained at cryogenic temperatures in water-glycerol samples. An isopiestic method has been developed to finely tune the hydration level of the system. We have combined FTIR spectral analysis of the combination and association bands of residual water with differential light-minus-dark FTIR and high-field EPR spectroscopy to gain information on thermodynamics of water sorption, and on structure/dynamics of the residual water molecules, of protein residues and of RC cofactors. The following main conclusions were reached: (i) the RC dynamics is slaved to that of the hydration shell; (ii) in dehydrated trehalose glasses inhibition of protein dynamics is most likely mediated by residual water molecules simultaneously bound to protein residues and sugar molecules at the protein-matrix interface; (iii) the local environment of cofactors is not involved in the conformational dynamics which stabilizes the P+QA-; (iv) this conformational relaxation appears to be rather delocalized over several aminoacidic residues as well as water molecules weakly hydrogen-bonded to the RC.
Sulfanyl Radical Addition to Alkynes: Revisiting an Old Reaction to Enter the Novel Realms of Green Chemistry, Bioconjugation, and Material Chemistry
Creators: name: Monesi, Alessandro <1983>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: CHIM/06 Chimica organica

description: In the last decade considerable attention has been devoted to the rewarding use of Green Chemistry in various synthetic processes and applications.
Green Chemistry is of special interest in the synthesis of expensive pharmaceutical products, where suitable adoption of “green” reagents and conditions is highly desirable. Our project especially focused in a search for new green radical processes which might also find useful applications in the industry. In particular, we have explored the possible adoption of green solvents in radical Thiol-Ene and Thiol-Yne coupling reactions, which to date have been normally performed in “ordinary” organic solvents such as benzene and toluene, with the primary aim of applying those coupling reactions to the construction of biological substrates. We have additionally tuned adequate reaction conditions which might enable achievement of highly functionalised materials and/or complex bioconjugation via homo/heterosequence. Furthermore, we have performed suitable theoretical studies to gain useful chemical information concerning mechanistic implications of the use of green solvents in the radical Thiol-Yne coupling reactions.
Men's Preferences Among Wool Suits, Coats, and Jackets
Creators: name: Division Of Special Surveys, Bureau Of Agricultural Economics
name: Division Of Special Surveys, Bureau Of Agricultural Economics
Publisher: name: Unknown
Year: 1951
Subjects: Institutional and Behavioral Economics
Research Methods/ Statistical Methods

description: Excerpts from the report Introduction: This study supplements a previous survey on men's clothing preferences made by the Bureau of Agricultural Economics. The first report dealt with men's preferences for business shirts, summer sport shirts, wool shirts, extra trousers, socks, summer suits, underwear, pajamas, robes, and raincoats. The present report deals only with year-round suits, sports jackets, topcoats and overcoats, and also differs from the former in the design of the questionnaire and the types of analysis. In order to meet the objective of a study of motivations the questions in the schedule dealt with actual experiences in suit buying, that is, what men did and had in mind when they bought their newest suits, or, if they owned sports jackets, how they happened to start wearing them. In addition to data on ownership and the conventional coding of preferences and explanations, the goals or values men thought they could attain through suits were explored through the content analysis method. Preferences for suitings of different grade wools were established through use of the method of paired comparisons.
Orthogonal subsets of classical root systems and coadjoint orbits of unipotent groups
Creators: name: Ignatyev, Mikhail V.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics

description: Let $Φ$ be a classical root system and $k$ be a field of sufficiently large characteristic. Let $G$ be the classical group over $k$ with the root system $Φ$, $U$ be its maximal unipotent subgroup and $\mathfrak{u}$ be the Lie algebra of $U$. Let $D$ be an orthogonal subset of $Φ$ and $Ω$ be a coadjoint orbit of $U$ associated with $D$. We construct a polarization of $\mathfrak{u}$ at the canonical form on $Ω$. We also find the dimension of $Ω$ in terms of the Weyl group of $Φ$. As a corollary, we determine all possible dimensions of irreducible complex represenations of the group $U$ for the case of finite field $k$.
description: 11 pages
Increased synthesis of pro-inflammatory cytokines in C9ORF72 patients
Creators: name: Pinilla, Gabriel
name: Kumar, Anupama
name: Floaters, Mary Kay
name: Pardo, Carlos A.
name: Rothstein, Jeffrey
name: Ilieva, Hristelina
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology

description: C9ORF72 hexanucleotide expansion is the most common genetic cause of familial amyotrophic lateral sclerosis (ALS)/fronto-temporal dementia (FTD) disease spectrum. Even though three major mechanisms of disease pathogenesis have been proposed, we lack detailed understanding of the factors that influence disease onset and progression. We sought to characterize cerebrospinal fluid and sera of C9ORF72 patients via a multiplex assay of 41 chemokines and cytokines in comparison to neurological controls and sporadic ALS patients. We found an increase in synthesis of pro-inflammatory chemokines and cytokines in disease samples and particularly in C9ORF72 patients in comparison to controls. We provide evidence that a CSF pro-inflammatory signature is a feature of C9ORF72–mediated disease.
SOD1-related ALS with anticipation in a large family from Martinique
Creators: name: Giguet-Valard, Anna-Gaelle
name: Bellance, Rémi
name: Jeannin, Séverine
name: Duclos, Sophie
name: Olive, Pascale
name: Allard-Saint-Albin, Oriane
name: Cazeneuve, Cécile
name: Clot, Fabienne
name: Sophie, Pittion-Vouyovitch
name: Barnetche, Thomas
name: Smith-Ravin, Juliette
name: Goizet, Cyril
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Evolutionary Biology
subject: Ecology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Amyotrophic Lateral Sclerosis (ALS) is a rare neurological disorder that causes degeneration of upper and lower motor neurons and their axons. ALS is mostly sporadic, but there are familial forms. In more than half of the familial forms, a pathogenic variant is found in one of the following genes: C9ORF72, SOD1, TDP-43, FUS, and VCP. SOD1 is the 2nd most common gene involved in genetic forms of ALS. Genotype–phenotype relationships are occasionally established in genetic forms of ALS associated with SOD1 mutations pathogenic variants. The c.281G > T (p.[G93V]) variant in SOD1 is associated with a rarely described and unexplained anticipation phenomenon. We report a large family from Martinique in whom ALS is associated with a c.281G > T (p.[G93V]) pathogenic variant in SOD1 and a statistically suggested anticipation. A whole-exome study and detection of CNVs (CoDESeq) from 3 affected members of this family revealed the presence of variants of uncertain signification (VUS) in other ALS genes. VUS in DCTN1 and NEFH were present in patients of the 2nd generation, and CNVs involving UBQLN2 and C21orf2 were found in the youngest case of the family.
title: Linfoma primario de intestino delgado:¿Qué debemos saber?
Creators: name: López Romero, Silvia
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Lymphoma
subject: CT
subject: Small bowel
subject: Abdomen

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
Describir las diferentes formas de presentación del linfomaprimario de intestino delgado y analizar las características radiológicas que permiten realizar un diagnóstico...
title: El retroperitoneo, ese gran desconocido: revisión de las principales masas retroperitoneales.
Creators: name: Paz Maya, Silvia
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Abdomen
subject: Anatomy
subject: Veins / Vena cava
subject: MR
subject: CT
subject: eLearning
subject: Neoplasia

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
Hacer una revisión anatómica de los espacios retroperitoneales. Analizar las características de la imagen TC o RM de las principales patologías del retroperitoneo,
incidiendo en las neoplasias...
On the Second Boundary Value Problem for a Class of Modified-Hessian Equations
Creators: name: von Nessi, Greg T.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35J60, 35J65

description: In this paper a new class of modified-Hessian equations, closely related to the Optimal Transportation Equation, will be introduced and studied. In particular, the existence of globally smooth, classical solutions of these equations satisfying the second boundary value problem will be proven. This proof follows a standard method of continuity argument, which subsequently requires various a priori estimates to be made on classical solutions. These estimates are modifications and generalise the corresponding estimates of Trudinger and Wang for the Optimal Transportation Equation. Of particular note is the fact that the global C^2 estimate contained in this paper makes no use of duality in regards to the original equation.
description: 30 pages. Article has now been published in Communications in Partial Differential Equations
A Arte Contemporânea em Diálogo com as Mídias e Tecnologias Digitais: Uma Reflexão Poética sobre a Transformação Social
Creators: name: Duarte, Felipe Bernardes
Publisher: name: Labfront/UEMG
Year: 2023

description: Este trabalho propõe uma reflexão poética sobre as relações entre arte, mídia e tecnologias digitais na contemporaneidade. Inspirados pelos conceitos de Nicolas Bourriaud, Lev Manovich e Peter Weibel, dedicados a compreender as possibilidades e os desafios da arte em meio às transformações tecnológicas e sociais, essa comunicação busca provocar o pensamento crítico e a sensibilidade poética do público, convidando-os ao engajamento em uma reflexão sobre a relação entre a arte, mídias e as tecnologias digitais. Através de exemplos de obras que utilizam as tecnologias digitais como as obras de Marco Brambilla, Wayne McGregor e Olafur Eliasson, este trabalho busca destacar a importância da arte como forma de expressão crítica e poética em meio ao ao cenário de possíveis crises de valores históricos, institucionais e culturais que são evidenciados por mudanças recepção de informação, na sua distribuição e impulsionados pela aceleração de produção de imagens e vídeos.
Direct $qqq$ Force In High Momentum Limit of QCD For Proton Physics
Creators: name: Mitra, An
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: An explicit construction of the proton wave function is outlined in the high momentum limit of QCD dominated by a direct $qqq$ force, one generated by hooking the ends of a $ggg$ vertex to 3 distinct ${\bar q}gq$ vertices, thus making up a $Y$-shaped diagram (see fig.1). The high degree of $S_3$ symmetry thus involved ensures that the $qqq$ wave function is a mixture of $56, 0^+$ and $20,1^+$ components, rather than the traditional $56, 0^+$ and $70, 0^+$ type. Some results of this paradigm shift are offered.
description: 6 pages, Presented at 4th International Symposium on Symmetries in Subatomic Physics at NTU, Taipei, 2009
Photometric Estimates of Redshifts and Distance Moduli for Type Ia Supernovae
Creators: name: Kessler, Richard
name: Cinabro, David
name: Bassett, Bruce
name: Dilday, Benjamin
name: Frieman, Joshua A.
name: Garnavich, Peter M.
name: Jha, Saurabh
name: Marriner, John
name: Nichol, Robert C.
name: Sako, Masao
name: Smith, Mathew
name: Bernstein, Joseph P.
name: Bizyaev, Dmitry
name: Goobar, Ariel
name: Kuhlmann, Stephen
name: Schneider, Donald P.
name: Stritzinger, Maximilian
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Large planned photometric surveys will discover hundreds of thousands of supernovae (SNe), outstripping the resources available for spectroscopic follow-up and necessitating the development of purely photometric methods to exploit these events for cosmological study. We present a light-curve fitting technique for SN Ia photometric redshift (photo-z) estimation in which the redshift is determined simultaneously with the other fit parameters. We implement this "LCFIT+Z" technique within the frameworks of the MLCS2k2 and SALT-II light-curve fit methods and determine the precision on the redshift and distance modulus. This method is applied to a spectroscopically confirmed sample of 296 SNe Ia from the SDSS-II Supernova Survey and 37 publicly available SNe Ia from the Supernova Legacy Survey (SNLS). We have also applied the method to a large suite of realistic simulated light curves for existing and planned surveys, including SDSS, SNLS, and LSST. When intrinsic SN color fluctuations are included, the photo-z precision for the simulation is consistent with that in the data. Finally, we compare the LCFIT+Z photo-z precision with previous results using color-based SN photo-z estimates.
description: accepted by ApJ
Ion transport and short circuit current in the rectum of the desert locust, Schistocerca gregaria
Creators: name: Williams, Douglas Lloyd
Publisher: name: University of British Columbia
Year: 2010

description: An in vitro preparation of the rectum of the desert locust Schistocerca gregaria is described and characterized. The rectal epithelium was mounted as a flat sheet separating two well stirred chambers and the trans-membrane potential difference (PD), membrane resistance, and short circuit current (SCC) were monitored. The PD and membrane resistance remained relatively constant for at least six hours at 35 mV (lumen positive) and 6000 Ohms . cm ⁻², respectively. After an initial two hour transient period during which the SCC dropped from 8 uMoles of charge .cm⁻² .hr⁻¹ to 3.5 uMoles. cm⁻² .h⁻¹ an approximate steady-state condition was reached and maintained for at least another four hours. The SCC was consistant with either a net cation transport from the hemolymph to the lumen of the rectum or a net anion transport in the opposite direction. Since Cl⁻ was the only major anion in the bathing media some experiments were carried out to evaluate the contribution of active Cl⁻ transport to the SCC. Substitution of SO4⁻ of NO3⁻ during the third and fourth hours in vitro had no effect on the SCC, although they abolished the initial two hours transient. Similar experiments in which Cl⁻ was substituted by acetate had a complex stimulatory effect on the SCC. Measurements of ³⁶Cl⁻ fluxes under SCC conditions during the same time period demonstrated a mean net flux of 1.52 uMoles of Cl⁻ cm⁻².hr from the rectal lumen to the hemolymph. This value is equivalent to one half the simultaneous SCC. These experiments clearly demonstrate that the rectal epithelium actively transports Cl⁻ in a direction consistent with the observed SCC but that this active transport of Cl⁻ does not contribute to the SCC during the third and fourth hours in vitro. Since rectal Na+ and K+ transport reported by other workers is in the wrong direction to account for the observed SCC, it seems necessary to propose (1) a Cl⁻ exchange pump (probably with HCO3⁻) perhaps located on the luminal membrane to account for the fact that active Cl⁻ transport does not contribute to the SCC and (2) a H+ and/or HCO3⁻ pump to account for the SCC. These proposals are incorporated in a model for organization of ion transport processes in the locust rectum.