cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Taphonomy, taxonomy and geoconservation of the ‘Upper Island Cove’ Ediacaran fossil assemblage
Creators: name: McKean, Christopher
Publisher: name: Memorial University of Newfoundland
publisherIdentifier: https://ror.org/04haebc03
publisherIdentifierScheme: ROR
Year: 2024

description: three-dimensional, high relief Ediacaran fossils on the Allison Surface, Upper Island Cove, were discovered 20 years ago. This project has implemented novel methods and modern understandings of the Ediacaran biota to improve our understanding of this under-studied site. Through the collection and assessment of taphonomic and sedimentological data it can be seen that the unique preservation of the assemblage was the result of erect and reclined fronds being encased in the top centimetre of a partly lithified Td silt, prior to subsequent exhumation by obstruction scours in the lee of a later community of erect organisms. After exhumation both the upper and lower surfaces of the fronds were cast by an overlying pyritic, fine-grained Tc sandstone which led to the high relief preservation. This improved understanding of site taphonomy, alongside the addition of over 150 newly discovered specimens, led to a taxonomic reassessment of the surface and the description of three new taxa: 1) Avalofractus dosomitus sp. nov., 2) Kannabuchia artkingii gen. et sp. nov. and 3) Corellia washageuis gen. et sp. nov. New morphotypes of Arborea, Bradgatia and Charnia have also been described from the surface, including for the first-time documentation of a differentiated upper surface in Bradgatia. The presence of unique taphonomic processes and endemic species on the Allison Surface highlight the importance of protecting the site. As such a novel approach to site observation was implemented at the surface, which shows that the fossils are at risk to both anthropic and environmental factors. The mitigation techniques that have been suggested to protect the site from irreparable damage can also be applied to other at-risk localities worldwide.
Transcriptional Targets of the REF-1 Family Proteins: HLH-25/ HLH-28/HLH-29
Creators: name: Wang, Kun
Publisher: name: Georgia State University
Year: 2011

description: Notch signaling is important for development in Caenorhabditis elegans and the REF-1 family pro-teins, a set of the bHLH transcription factors, are the first targets of Notch signaling. Little is known about the molecular mechanisms employed by the REF-1 family to regulate development. In this project, I iden-tified novel targets of three REF-1 family proteins, HLH-25/HLH-28/HLH-29, and determined which target genes are activated and which are repressed by the REF-1 proteins. These targets were identified by gene expression microarray and were functionally categorized by Gene Oncology analysis. A systems biology approach was performed to identify networks associated with those targets. In addition to the mo-lecular genetics studies, I identified and better characterized the range of phenotypes induced by muta-tions in ref-1 family genes.
Cours Research4Life, DOAJ, ASSAf. Module 1 : Introduction et vue d'ensemble du DOAJ
Creators: name: García Reátegui, Gala
Publisher: name: Zenodo
Year: 2024
Subjects: open access
science ouverte

description: Voici le matériel du Module 1 du cours accrédité sur les revues en accès ouvert.

Ce cours a été réalisé en collaboration avec Research4Life, le DOAJ et l'ASSAf.
Statuspapier Mikroplastikanalytik - Zusammenstellung wesentlicher Untersuchungsverfahren zur Probenahme, Aufbereitung und Detektion von Mikroplastik
Creators: name: Braun, Ulrike
name: Stein, Ulf
name: Schritt, Hannes
Publisher: name: My University
Year: 2021
Subjects: Gewässerboden
Klärschlamm
Kunststoff
Mikroplastikpartikel
Partikel
Polymer

description: Unter Mikroplastik sind Partikel, hauptsächlich bestehend aus synthetischen Polymeren, in der Dimension von 1-1000 (micro)m zu verstehen. Sie sind mittlerweile in der Umwelt allgegenwärtig, z.B. in Gewässern, Böden, Sedimenten und Luft, aber auch in Abwässern, Klärschlamm, Kompost und Lebensmitteln. In Umweltproben lassen sich in der Regel wenig große Partikel und sehr viele kleine Partikel von sehr unterschiedlicher Gestalt und chemischer Zusammensetzung identifizieren. Das macht ihre systematische Erfassung vergleichsweise aufwändig, sodass es eines guten Zusammenspiels verschiedener Verfahren bedarf. Obwohl die Charakterisierung von Plastik und von Partikeln seit Jahren etabliert ist, ist das Feld der Mikroplastikanalytik vergleichsweise jung. Daher müssen viele Verfahren erst noch hinsichtlich ihrer Eignung validiert werden. Es bestehen derzeit noch keine harmonisierten Protokolle. Das Statuspapier Mikroplastikanalytik fasst die Ergebnisse der Verbundprojekt-übergreifenden Diskussionen und Abstimmungen innerhalb des BMBF Forschungsschwerpunkts "Plastik in der Umwelt" zusammen. Es ist auf der Webseite des Forschungsschwerpunkts (https://www.bmbf-plastik.de/ index.php/de/publikationen) in deutscher und englischer Sprache zur Verfügung gestellt. © Authors
Colonial fault lines : First Nations autonomy and Indigenous lands in the time of COVID-19
Creators: name: Flynn, Alexandra
name: Shanks, Signa Daum
Publisher: name: The University of British Columbia
Year: 2023

description: The COVID-19 crisis has exposed the political and economic fault lines in the exercise of power across multiple jurisdictions. This article focuses on the power of First Nations to make enforceable decisions in respect to reserve lands. We argue that Canadian law both enables First Nations to assert jurisdiction in respect to their lands, yet undermines Indigenous authority in relation to enforcement and intergovernmental status.
Mechanismen der Veränderung von Organisationen
Creators: name: Martin, Albert
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2020
Subjects: classificationCode: 330
subject: 330 Wirtschaft

description: Die vorliegende Schrift beschäftigt sich mit „Mechanismen“, die das Organisationsgeschehen prägen. Exemplarisch geht es dabei um Mechanismen, die für einen tiefgreifenden Wandel von Organisationen verantwortlich sind. Zunächst geht es um eine Klärung des Mechanismusbegriffs und darum, inwiefern die Betrachtung von Mechanismen dazu beitragen kann, soziale Prozesse besser zu verstehen. Anschließend werden 36 Mechanismen vorgestellt. Die Beschreibung dieser Mechanismen stützt sich auf theoretische Ansätze, die sich explizit oder implizit mit Fragen des organisationalen Wandels befassen. Abschließend erfolgt eine kurze Erörterung der Frage nach einer Forschungsstrategie, die geeignet ist, die Mechanismenbetrachtung für die theoretische Forschung nutzbar zu machen.
Arbeitsbedingungen und Arbeitserleben von Arbeitnehmern und Unternehmern : Auswertungen der CATI-Befragung des European Working Conditions Survey (EWCTS) 2021
Creators: name: Martin, Albert
name: Bartscher-Finzer, Susanne
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2023
Subjects: classificationCode: 331
subject: 331 Arbeitsökonomie

description: Wenn in empirischen Studien nach der Arbeitszufriedenheit gefragt wird, dann zielen die verwen-deten Fragen in aller Regel auf die gesamthafte Beurteilung der Arbeitssituation und nicht etwa auf das mit der Arbeitstätigkeit verbundene Gefühlserleben. Um letzteres geht es im vorliegenden Bericht. Das Arbeitserleben ist zweifellos ein wichtiges Element, das in die Beurteilung der Arbeits-situation einfließt, es ist aber nur ein – wenngleich bedeutsamer – Faktor unter vielen anderen, die die Arbeitszufriedenheit bestimmen. Als Analysebasis dienen die Daten der Telefonumfrage des European Survey of Working Conditions (EWCTS) von 2021 in 36 europäischen Ländern. Er-gänzend werden die Daten des European Survey of Working Conditions (EWCS) von 2015 analy-siert. Berichtet wird über die Unterschiede im Arbeitserleben von Unternehmern und Arbeitneh-mern. Außerdem wird untersucht, welche Belastungsfaktoren auf das Arbeitserleben einwirken. Auf der Basis der Analyseergebnisse wird ein allgemeines Verhaltensmodell entwickelt, das, neben der Erlebniskomponente, auch die Urteilskomponente enthält. Das Arbeitserleben und die Zufrie-denheit mit den Arbeitsbedingungen werden danach ganz wesentlich von der Wertschätzung be-stimmt, die man für seine Arbeit erfährt. Die Arbeitsbelastungen und die Autonomie spielen dage-gen kaum eine Rolle. Das mindert allerdings nicht die grundsätzliche Bedeutung dieser beiden Va-riablen. Die diesbezüglich schwachen Korrelationen finden ihren Grund mutmaßlich im engen Re-ferenzrahmen der subjektiven Skalierung.
The Effects of Testicular Nerve Transection and Epididymal White Adipose Tissue Lipectomy on Spermatogenesis in Syrian Hamster
Creators: name: Spence, Jeremiah
Publisher: name: Georgia State University
Year: 2008

description: Previous investigators demonstrated that epididymal white adipose tissue (EWAT) lipectomy suppressed spermatogenesis and caused atrophy of the seminiferous tubules. EWAT lipectomy, however, may disrupt testicular innervation, which reportedly compromises testicular function. To resolve this confound and better clarify the role of EWAT in spermatogenesis, three experimental groups of hamsters were created in which: i.) the superior and inferior spermatic nerves were transected (SSNx) at the testicular level, ii.) EWAT was extirpated (EWATx), and iii.) testicular nerves and EWAT were left intact (SHAM controls). It was hypothesized that transection of the superior and inferior spermatic nerves would disrupt normal spermatogenesis. The findings indicate a significant reduction in spermatogenic activity and marked seminal tubule atrophy within the EWATx testis, as compared to the SSNx and controls testes, which did not differ significantly from each other. From these data, it is concluded that EWAT, and not testicular innervation, is central to normal spermatogenesis.
Actions of Selective Estrogenic Drugs Implanted Into the Medial Amygdala on Male Rat Mating Behavior
Creators: name: Dunigan, Anna
Publisher: name: Georgia State University
Year: 2012

description: Estrogen stimulation of the medial amygdala (MEA) of the brain promotes male rat mating behavior. However, selective stimulation of either of the estrogen receptor subtypes found in the MEA (ERà or ER?) does not support mating behavior. We tested the hypothesis that dual stimulation of ERà and ER? is required to activate estrogen-dependant neural circuits in the MEA responsible for mating by local treatment of MEA with a combination of selective estrogenic agonists: propyl pyrazole triol (PPT, an ERà agonist ) and diarylpropionitrile (DPN, an ER? agonist) administered to castrated, DHT maintained male rats. Estradiol (E2) or cholesterol (Chol) MEA implants served as positive and negative controls respectively. The animals receiving a mixture of PPT and DPN into the MEA displayed higher levels of mating behavior than the Chol treated animals but lower levels of mating behavior than the E2 treated animals.
title: 2020: Band 2, Heft 01
Creators: name: :None
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2020
Subjects: subject: 800
subject: 320

description: Welcome to the first 2020 issue of Diamonds in the Rough. This issue showcases the talents of Marlene Bechtold, Elisavet, Cihan Evran, Jolanda Friedrich, Steven, Svenja Krautwald, Kyra Meyer, and Eva Schumann. These first-year students have been trained to follow an idea, to defend their beliefs, to write so that it remains possible for a reader to disagree, and to put their opinions first, not last. Our issue explores the personal as well as the political. Covering urban sketching, the perfect Döner, poetry, writing as a help toward making life choices, and magical worlds, our authors also respond to the world of COVID-19, the Black Lives Matter movement, and the costs of taking any side in politics. Starting with this issue, the magazine offers a Pandemic Journal. All are invited to contribute for as long as we’re coping with COVID.
description: Diamonds in the Rough: A Literary Magazine, vol. 2, no. 01
Distribution of FABP7 in Neural Tissue of Socially Defeated Adult Anolis Carolinensis
Creators: name: Ca¤ete, Carmenada
Publisher: name: Georgia State University
Year: 2012

description: Due to its significance in many cellular functions, fatty acid binding protein 7 (FABP7) has become a rising topic of interest for many scientists. Immunocytochemistry was used to map the distribution of FABP7 and test whether the amount of FABP7 immunoreactivity (FABP7-IR) differed in animals that were defeated in a fight, as compared to control animals that did not engage in any social interaction. The male green anole was used as the subject because its natural tendency to establish social classes within its species provides an ideal model to observe for variation in FABP7-IR. The results showed FABP7-IR in cells and fibers of the cortex, hypothalamus, thalamus, medial preoptic area, dorsoventricular ridge, amygdala, suprachiasmatic nucleus, nucleus accumbens, nucleus rotundus, habenular area, tectum, dorsal noradrenergic and lateral forebrain bundles, and lining the third and lateral ventricles. Qualitative observation suggested higher FABP7 levels in socially defeated males than controls in all areas.
Vision eines elektronischen Dokumentensafes
Creators: name: Lucke, Jörn von
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2004
Subjects: Dokumentenverwaltungssystem
Verwaltungsakt
Verwaltungsinformatik

description: Der Aufsatz wurde anlässlich der Emeritierung von Prof. Dr. Reinermann im Oktober 2003 veröffentlicht. Er beschreibt den Einsatz elektronischer Aktenverwaltungssysteme.
Nature Inspired Strategy To Capture Smoky Carbon Dioxide Into Commercial Carbonates And Add Value To Farming
Creators: name: Hernandez, Jesus Ernesto
Publisher: name: Zenodo
Year: 2024
Subjects: carbon dioxide
commercial carbonates
carbon capture
solid carbonates
sustainability
waste into wealth

description: Air pollution is linked to the climate change crisis threatening life on Earth. The technologies for managing the rising concentration of atmospheric carbon dioxide are insufficient and mostly non-holistic. Amine scrubbing and the bury-and-hide approaches have led the way, whereas biocatalysed treatment has potential. However, these technologies could be more polluting (and more disordered DS > 0). Therefore, there is growing interest in holistic designs based on bioinspired solutions. The problem is complex and requires innovative designs that break disciplinary boundaries. Methods in this work consider: 1) the use of natural carbonic anhydrase from bovine blood waste to accelerate carbon conversion into carbonates up to 1 million molecules per second; 2) the use of real untreated smoke instead of the traditional, yet unrealistic, pristine CO2 approach (smoke is hot, sticky, corrosive and carries momentum, nitrogen, soot and toxic molecules harmful to most technologies, including biological); 3) at the heart of this work is the novel Cloud C concept, where a synthetic aqueous cloud simultaneously enhances the bioreactive absorption of smoky carbon and 4) the reduction of energy and water to produce commercial carbonates. Results showed that the amount of captured smoky CO2 doubled compared to its traditional counterpart. Moreover, 98% of the water was recovered and recycled after rapid natural precipitation of carbonates. This approach is safer for avoiding technologies linked to the high temperatures and pressures of amine scrubbing and geological capture and storage while valorising wastes. In addition, it avoids the use of fossil amines and natural or synthesised anhydrases, ultimately depending on feedstocks from fossil raw materials, or renewables generating more pollution linked to land-use change. Carbonates can be used in more than 500 commercial applications. This wholistic nature-inspired approach presents opportunities in harmony with climate change mitigation, circular economy and sustainability.
The influence of stellar activity on detecting Earth-like planets via nulling interferometry
Creators: name: Zhou, Rui-Si
name: Liu, Hui-Gen
name: Zhou, Li-Yong
Publisher: name: arXiv
Year: 2025
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The direct imaging of Earth-like planets in solar neighbors is challenging. Both transit and radial velocity (RV) methods suffer from noise due to stellar activity. By choosing a typical configuration of an X array interferometer, we used theoretical formulas to calculate the intrinsic Poisson noise and the noise of stellar activities. Assuming a fixed array with no rotation and ignoring other systematic and astrophysical noises, we considered a single active region on a stellar disk, including both spots and flares with different parameters, for instance, the position, size, and temperature of the active regions. Then we simulated the S/N of Earth-like planets in HZ around G dwarf stars (solar-like) and M dwarfs (Proxima-like), with different stellar activities in the mid-infrared (MIR) band ( 7-12 $μ$m). The noise attributed to stellar activity has much less influence than the Transit and RV method when detecting Earth-like planets around both G and M dwarfs. I.e. Stellar activity can hardly influence the detection of Earth-like planets around G dwarf stars. However, detecting Earth-like planets around M dwarfs, which are usually more active, can be significantly hindered. We also analyzed the uncertainty of the planet's location due to the deduced S/N. Consequently, we have determined the possibility of mistaking a planet in the HZ as being outside the HZ based on an erroneous S/N measurement. Selecting quiescent target stars or monitoring the light curves of stars would be a helpful way to get rid of contaminates associated with violent stellar activities.
description: 12 pages, 14 figures, accepted by A&A
title: 1918–1968–2018. Geschlechter(un)ordnungen in interdisziplinärer Perspektive: Bericht zur Jahrestagung des Netzwerks Frauen- und Geschlechterforschung NRW am 19.10.2018 in Essen
Creators: name: Beaufaÿs, Sandra
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2018
Subjects: subject: 300

description: Journal Netzwerk Frauen- und Geschlechterforschung NRW, vol. 2018, no. 43, p. 19
Preterm mothering in neonatal nurseries: Exploring what is and what could be through feminist design sociology
Creators: name: Byrt, Adrienne Elizabeth
Publisher: name: Swinburne
Year: 2024

description: Using feminist design sociology, this qualitative research explored the childbirth and extended hospitalisation experiences of 19 mothers of premature children living in Australia. Findings revealed gendered expectations placed on women after premature childbirth, such as individualised maternal responsibility and limited parental leave for partners. This thesis expands on these gendered burdens and demonstrates how future iterations of the design of an improved support service for mothers of premature infants within hospital settings must resist the reproduction of the idea that once women give birth, they must take on most of the caregiving work.
MC3R and MC4R Knockdown via RNA Interference
Creators: name: Mankin, Danielle
Publisher: name: Georgia State University
Year: 2012

description: Melanocortins (MCs) play an important role in feeding, metabolism, and energy expenditure. While melanocortin receptor (MCR) mRNA has been found in the mesolimbic dopamine (DA) pathway, the ability of melanocortins to regulate feeding and other behaviors through actions on the mesolimbic DA system have not been examined. Short-hairpin RNAs (shRNAs) were created targeting MC3R and MC4R and were tested via in vitro studies for their ability to knockdown their target receptor. A total of three shRNAs were created targeting each receptor, and each shRNA caused successful knockdown. These shRNAs are tools that can be used for future in vivo studies to examine the various behavioral effects of melanocortins on the mesolimbic DA pathway.
title: 100 Jahre Frauenwahlrecht: politische Repräsentanz und der Gender Gap in der Demokratie
Creators: name: Wiechmann, Elke
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2018
Subjects: subject: 300

description: Journal Netzwerk Frauen- und Geschlechterforschung NRW, vol. 2018, no. 43, p. 22
title: Staatsbürgerinnenschaft unter Vorbehalt: reproduktive Politiken und Geschlechterdemokratie
Creators: name: Lembke, Ulrike
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2018
Subjects: subject: 300

description: Journal Netzwerk Frauen- und Geschlechterforschung NRW, vol. 2018, no. 43, p. 28
Is the Cytoskeleton Necessary for Viral Replication?
Creators: name: Morgan, Rachel
Publisher: name: Georgia State University
Year: 2012

description: The cytoskeleton plays an important role in trafficking proteins and other macromolecular moieties throughout the cell. Viruses have been thought to depend heavily on the cytoskeleton for their replication cycles. However, studies, including one in our lab, found that some viruses are not inhibited by anti-microtubule drugs. This study was undertaken to evaluate the replication of viruses from several families in the presence of cytoskeleton-inhibiting drugs and to examine the intracellular localization of the proteins of one of these viruses, Sindbis virus, to test the hypothesis that alternate pathways are used if the cytoskeleton is inhibited. We found that Sindbis virus (Togaviridae, positive-strand RNA), vesicular stomatitis virus (Rhabdoviridae, negative-strand RNA), and Herpes simplex virus 1 (Herpesviridae, DNA virus) were not inhibited by these drugs, contrary to expectation. Differences in the localization of the Sindbis virus were observed, suggesting the existence of alternate pathways for intracellular transport.
Supplementary document for Quantitative and anatomical imaging of dermal angiopathy by noninvasive photoacoustic microscopic biopsy - 5439010.pdf
Creators: name: ma, hai
name: cheng, zhong
name: Wang, Zhiyang
name: Qiu, Haixia
name: Shen, Tianding
name: Xing, Da
name: Gu, Ying
name: Yang, Sihua
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
Is TGF-? Playing a Role In Ectopic Neuromuscular Junction Formation in the Nematode Caenorhabditis Elegans?
Creators: name: Rahman, Abir
Publisher: name: Georgia State University
Year: 2012

description: The neuromuscular junction (nmj) is a commonly studied synapse, used often to investigate reciprocal signaling between a motor neuron and the appropriate target muscle. In Caenorhabditis elegans, ectopic nmjs can be created by eliminating selected embryonic muscle cells that act as guideposts for the migration of post-embryonic muscles. The ectopic muscles are required to induce sprouting from DD motor neurons, indicating the presence of a muscle derived signaling molecule that interacts with the neurons. A TGF-? homolog, unc-129, is reported to be transiently expressed in the dorsal body wall muscles. The timing of the expression of TGF-? coincides with the time that the DD motor neurons respecify their synapses. In this study, we show that TGF-? is expressed by the ectopic muscle and that in unc-129 mutant animals, the ectopic muscle is unable to induce sprouting from the DD motor neurons. Therefore, we conclude that TGF-? is necessary for ectopic nmj formation in C.elegans.
title: Let’s talk about: Utopien
Creators: name: Sanyal, Mithu
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2018
Subjects: subject: 300

description: Journal Netzwerk Frauen- und Geschlechterforschung NRW, vol. 2018, no. 43, p. 37
title: Von JETZT aus einen Blick in die Zukunft: 100 Jahre Zeitzeug_innen
Creators: name: Schmidt, Uta
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2018
Subjects: subject: 300

description: Journal Netzwerk Frauen- und Geschlechterforschung NRW, vol. 2018, no. 43, p. 42
title: Recognizing Partial Textual Entailment
Creators: name: Levy, Omer
name: Zesch, Torsten
name: Dagan, Ido
name: Gurevych, Iryna
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2013
Subjects: subject: 004

description: Textual entailment is an asymmetric relation between two text fragments that describes whether one fragment can be inferred from the other. It thus cannot capture the notion that the target fragment is “almost entailed” by the given text. The recently suggested idea of partial textual entailment may remedy this problem. We investigate partial entailment under the faceted entailment model and the possibility of adapting existing textual entailment methods to this setting. Indeed, our results show that these methods are useful for recognizing partial entailment. We also provide a preliminary assessment of how partial entailment may be used for recognizing (complete) textual entailment.
Adenovirus Death Protein: The Switch Between Lytic and Persistent Infections in Lymphocytes?
Creators: name: Murali, Vineeth Kumar
Publisher: name: Georgia State University
Year: 2012

description: Adenovirus Death Protein (ADP) expression during late stages of a lytic infection releases mature virions to promote viral spread, thus leading to death of the host cell. We sought to investigate ADP expression patterns in persistently infected human lymphocytes cells. We hypothesized that low expression of ADP allows the virus to persist while high expression would promote lytic infection in lymphocytes. Accordingly, we found ADP expressed in low amount in BJAB and KE37 cells, while lytically infected Jurkat cells demonstrated higher ADP expression in both protein and transcript levels. ADP overexpression in persistently infected lymphocytes did not alter the viability of these cells, or their level of ADP expression. In contrast, Jurkat cells infected with an ADP-deleted virus had increased survival and maintained viral DNA for greater than 1-month, suggesting conversion to a persistent infection. Also manipulating ADP expression had minimal impact on the total virus yield from infected lymphocytes.
Modulation of Local Reflexes During Centrally Commanded Movements
Creators: name: Tahir, Uzma
Publisher: name: Georgia State University
Year: 2013

description: During centrally orchestrated movements, the nervous system must distinguish between appropriate and inappropriate reflexes. I studied local postural flexion reflexes of the crayfish that are evoked by unexpected touch. An isolated abdomen was used which permitted recording and stimulating of tailfan afferents, nerve cord interneurons, and postural motor neurons. Stimulation of the afferents evoked a postural flexion response of the medium tonic and large phasic motor neurons of the superficial flexor nerve; a flexion motor program was then excited by stimulating descending interneurons. Afferent stimulation evoked a smaller motor response during the motor program than before or after. These results indicate that the postural reflex responses to sensory stimulation are inhibited at a site presynaptic to the motor neurons during the flexion motor program. Application of Picrotoxin (blocked inhibition) to the primary afferent-to-mechanosensory interneuron synapse did not prevent the modulation of the postural flexion reflex during the flexion motor program.
Abfallvermeidung von Textilien
Creators: name: Müller, Katrin
name: Gimkiewicz, Jan
name: Schlüter, Anna
name: Friedrich, Caroline
name: Kummer, Sina
name: Röhreich, Mareike
name: Stechemesser, Kirstin
name: Zietlow, Brigitte
Publisher: name: Umweltbundesamt
Year: 2021
Subjects: subject: Abfallvermeidung
subject: Ressourcenschonung
subject: Kreislaufwirtschaft
subject: Textilien
subject: Beschaffung
subject: Bekleidung
subject: Nachhaltiger Konsum
subject: Wirtschaft | Konsum
subject: Abfall | Ressourcen

description: Der Textilsektor ist von einer Vielzahl an gesetzlichen Regelungen, Leitfäden, Strategien, Umweltzeichen und Siegel betroffen, die es für Akteurinnen und Akteure zu beachten gilt bzw. die beachtet werden können. Das folgende Dokument hat das Ziel, einen Überblick über die bestehenden bzw. anstehenden gesetzlichen Regelungen, Leitfäden, Strategien, Umweltzeichen und Siegel zu Textilprodukten in der Europäischen Union und in Deutschland zu geben. Die Übersicht richtet sich hauptsächlich an Unternehmen, Wirtschaftsakteure und Umweltorganisationen. Das Dokument bildet insgesamt 13 Kapitel ab. Diese umfassen den Einsatz von chemischen Stoffen, Abfallmanagement, Beschaffung und Nachhaltigkeit. Zudem werden Siegel und Kennzeichnungen vorgestellt. Neben einer Zusammenfassung sind ebenfalls weiterführende Links bereitgestellt. Quelle: www.umweltbundesamt.de
description: Der Textilsektor ist von einer Vielzahl an gesetzlichen Regelungen, Leitfäden, Strategien, Umweltzeichen und Siegel betroffen, die es für Akteurinnen und Akteure zu beachten gilt bzw. die beachtet werden können. Die Broschüre gibt hierüber für Deutschland und der Europäischen Union einen Überblick und richtet sich hauptsächlich an Unternehmen, Wirtschaftsakteure und Umweltorganisationen. Angesprochen werden unter anderem der Einsatz von chemischen Stoffen, Abfallmanagement, Beschaffung und ⁠Nachhaltigkeit⁠ sowie Siegel und Kennzeichnungen. Ebenfalls werden weiterführende Links bereitgestellt.
title: Bei Adam und Eva anfangen. Theologische Frauen- und Genderforschung mit der Bibel: Abschiedsvorlesung am 06. Juli 2018 an der Universität Münster
Creators: name: Wacker, Marie-Theres
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2018
Subjects: subject: 300

description: Journal Netzwerk Frauen- und Geschlechterforschung NRW, vol. 2018, no. 43, p. 46
Recommendations for the conduct of systematic reviews in toxicology and environmental health research (COSTER)
Creators: name: Whaley, Paul
Publisher: name: Zenodo
Year: 2020
Subjects: systematic review
research standards
environmental health
toxicology
recommendations

description: Presentation giving an overview of the following information about the COSTER recommendations: What is COSTER and why is it needed? How was COSTER developed? How to use COSTER? How does COSTER compare to other SR standards? Discussion points and FAQs Next steps in developing COSTER
title: UKP-BIU: Similarity and Entailment Metrics for Student Response Analysis
Creators: name: Zesch, Torsten
name: Levy, Omer
name: Gurevych, Iryna
name: Dagan, Ido
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2013
Subjects: subject: 004

description: Our system combines text similarity measures with a textual entailment system. In the main task, we focused on the influence of lexicalized versus unlexicalized features, and how they affect performance on unseen questions and domains. We also participated in the pilot partial entailment task, where our system significantly outperforms a strong baseline.
Neural Crosstalk Between Sympathetic Nervous System and Sensory Circuits to Brown Adipose Tissue
Creators: name: Liu, Yang
Publisher: name: Georgia State University
Year: 2013

description: Brown adipose tissue (BAT) is a critical organ for non-shivering thermogenesis, which is under control of both sympathetic and sensory neural innervation. We utilized both a retrograde sympathetic nerve tract tracer pseudorabies virus and an anterograde sensory tract tracer the H129 strain of herpes simplex virus-1 to locate individual neurons across the neuroaxis that are part of the SNS outflow from brain to interscapular BAT and are part of the sensory input to the brain. We found specific neuronal phenotype of the double-infected neurons distributed from the hindbrain to the forebrain with highest densities in several discrete brain regions: the paraventricular hypothalamus (PVH), lateral hypothalamus (LHA), parabrachial nucleus (PB) and raphe pallidus (RPa). The neuroanatomical reality of the SNS-sensory feedback loops suggests coordinated control of BAT thermogenesis at several sites and indicates plasticity of SNS-sensory crosstalk.
title: Warum gibt es so wenige Professorinnen in der Rechtswissenschaft?
Creators: name: Schultz, Ulrike
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2018
Subjects: subject: 300

description: Journal Netzwerk Frauen- und Geschlechterforschung NRW, vol. 2018, no. 43, p. 56
Mechanisms of Localization of Symbiont-produced Natural Products in Host Colony
Creators: name: Akhter, Fahmina
Publisher: name: Georgia State University
Year: 2013

description: The relationship between the bryozoan Bugula neritina and its symbiont "Candidatus Endobugula sertula" is a specific yet complex model for defensive symbiosis where the host larvae obtain chemical protection from predation by symbiont-produced bryostatin. The symbiotic bacteria are located in both larval and adult tissues of the host. However, the bryostatins levels are higher in larvae and in adult zooids with ovicells where the larvae are brooded, compared to adult zooids without ovicells. In this study, symbiont cell density and bryostatin biosynthetic gene expression were quantified in host tissues, using TaqMan probe based Q-PCR, to investigate the mechanisms for the higher bryostatin content in larvae. The results showed that there are no significant differences of the symbiont cells in three tissues and the bryostatin gene expression is not different in ovicell-bearing zooids as compare to ovicell-free zooids suggesting that the host plays a role in transferring bryostatin to larvae.
Metabolic phenotypes and risk of colorectal cancer: a systematic review and meta-analysis of cohort studies
Creators: name: Goodarzi, Golnoosh
name: Mozaffari, Hadis
name: Raeisi, Tahereh
name: Mehravar, Fatemeh
name: Razi, Bahman
name: Ghazi, Maryam L.
name: Garousi, Nazila
name: Alizadeh, Shahab
name: Janmohammadi, Parisa
Publisher: name: BioMed Central
Year: 2022

description: Background The association of obesity with colorectal cancer (CRC) may vary depending on metabolic status. Objective This meta-analysis aimed to investigate the combined impacts of obesity and metabolic status on CRC risk. Methods The Scopus, PubMed, and web of sciences databases were systematically searched up to Jun 2021 to find all eligible publications examining CRC risk in individuals with metabolically unhealthy normal-weight (MUHNW), metabolically healthy obesity (MHO), and metabolically unhealthy obesity (MUHO) phenotypes. Results A total of 7 cohort studies with a total of 759,066 participants were included in this meta-analysis. Compared with healthy normal-weight people, MUHNW, MHO, and MUHO individuals indicated an increased risk for CRC with a pooled odds ratio of 1.19 (95% CI = 1.09–1.31) in MUHNW, 1.14 (95% CI = 1.06–1.22) in MHO, and 1.24 (95% CI = 1.19–1.29) in MUHO subjects. When analyses were stratified based on gender, associations remained significant for males. However, the elevated risk of CRC associated with MHO and MUHO was not significant in female participants. Conclusions The individuals with metabolic abnormality, although at a normal weight, have an increased risk for CRC. Moreover, obesity is associated with CRC irrespective of metabolic status.
Rational Design, Synthesis, and Evaluation of Inhibitors for the HIV-1 TAT Interacting Protein Tip60
Creators: name: Ngo, Liza
Publisher: name: Georgia State University
Year: 2013

description: The histone acetyltransferase protein, Tip60, has many important functions in epigenetic regulation of gene expression and DNA repair. Our objective is to design, synthesize, and evaluate potent inhibitors for Tip60. Full-length Tip60 (fl-Tip60) and catalytic domain of Tip60 (cat-Tip60) were expressed in E. coli and purified with nickel affinity chromatography. Quantitative analysis of enzyme activities demonstrated that both enzyme forms had very high activity with the substrate H4. To create new Tip60 inhibitors, various histone H3 peptides conjugated with CoA were synthesized using the Fmoc solid-phase peptide synthesis and solution phase synthesis protocols. The results from the inhibition radioactive assay showed that the synthetic H3-CoA conjugates inhibited effectively the enzymatic activity of both fl-Tip60 and cat-Tip60; and the addition of methyl groups to the Lys-4 or Lys-9 residue of H3 aided in a 7-9 fold enhancement in potency in comparison to nascent H3-CoA inhibitor.
In Silico Analysis Shows That Single Aminoacid Variations In Rhesus Macacque Fc?receptor Affect Protein Stability And Binding Affinity To IgG1
Creators: name: Sanghvi, Rashesh
Publisher: name: Georgia State University
Year: 2013

description: Rhesus macaques are a widely used animal model of human diseases and related immune responses.   Fc receptors (FcRs) mediate the interaction between antibody molecules and innate killing mechanisms, consequently eliminating the pathogen.   In rhesus macaques, FcRs are highly polymorphic.   To evaluate the potential influence of FcgR polymorphisms on the interaction with antibody molecules, we performed in silico analysis using SIFT, Provean, nsSNPAnalyzer, I-Mutant, MuSTAB and iPTREE-STAB web servers.   V20G in Fc?RI, I137K in Fc?RII and I233V in Fc?RIII were further analyzed structurally using FOLD-X, AMMP and Chimera to calculate changes in folding and interaction energy and for structure visualization.   Results from our analysis suggest that the selected variations destabilize protein structure.   Additionally, Q32R increases the binding affinity of Fc?RI, whereas A131T decreases the binding affinity of Fc?RII towards IgG1.   Together, our results indicate that these substitutions might influence effector and regulatory mechanisms resulting from antibody/FcR interactions.
SOCIAL MEDIA DIGITAL NEW FORM OF INTEGRATED EDUCATION
Creators: name: Pazilova, Dilnoza
Publisher: name: Zenodo
Year: 2024

description: Information and communication technologies are essential in the modern educational process. Integrating social media into education is alternative to support teaching and learning activities, both formal and informal. Higher education in the Republic Uzbekistan Empirical research on professional use of social media in educational settings is rare . The purpose of this article is to study aspects of the use of social networks in educational institutions as a new form of educational process and their influence on professional development. The research method is based on questionnaires. It was created online using Survey Monkey as _ instrument _ Questionnaire was developed based on a qualitative study involving two groups on the most important aspects of social networks as a new educational process . 100 teachers took part in the study . results show that _ at transition from IT use from Web 1.0 to Web 2.0, teachers share information, use social networking platforms at different levels and make significant contributions to development education in virtual environment
DesigningTargeted F4/80 Antibody Coated TNF-à siRNA Loaded Nanoparticles: A Novel Therapeutic Approach To Treat Inflammatory Bowel Disease
Creators: name: Rakhya, Poonam
Publisher: name: Georgia State University
Year: 2013

description: Today, increasing evidences of systemic side effects with the treatments available for IBD limit their therapeutic outcomes. The challenge is to target anti-TNF-à agent to the inflamed tissue. Here, we have demonstrated that TNF-à siRNA can be efficiently loaded into F4-80 antibody (Ab) coated PLA-PEG-Mal nanoparticles (NPs) to target colonic macrophages (MPs). The NPs were characterized for particle size, cytotoxicity, binding characteristics, etc. These NPs are ~600 nm in diameter, non-cytotoxic, and are efficiently taken up by MPs inhibiting TNF-à secretion by the MPs in vitro. In vivo, the release of TNFa siRNA loaded inside F4/80 Ab coated NPs into colitis mice model showed higher colitis attenuation (like reduced weight loss, MPO activity and neutrophils infiltration) when compared to NPs not covered. Thus, we have formulated an efficient targeted drug delivery system in which TNF-à-siRNA NPs coated with F4/80 Ab represent an efficient therapeutic option for diseases such as IBD.
Polycomb Recruitment at the Class II Transactivator
Creators: name: Boyd, Nathaniel
Publisher: name: Georgia State University
Year: 2013

description: The Class II Transactivator (CIITA), is the master regulator of Major Histocompatibility Class II (MHC II) genes. Transcription of CIITA is characterized by a decrease in specific trimethylation of histone H3 lysine 27 (H3K27me3), catalyzed by the histone methyltransferase Enhancer of Zeste Homolog 2 (EZH2). While EZH2 is the known catalytic subunit of the Polycomb Repressive Complex 2 (PRC2) and is present at the inactive CIITA promoter; the mechanisms of recruitment of PRC2 to mammalian promoters remains unknown. Here we identify two DNA-binding proteins, YY1 and Jarid2, which interact with and regulate PRC2 recruitment to CIITA promoters. Our study is the first to identify novel roles of YY1 and Jarid2 in the epigenetic regulation of a mammalian gene by the PRC2.
title: „I cannot imagine a world in which gender makes no difference“ – Richard Dyer im Gespräch
Creators: name: :None
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2018
Subjects: subject: 300

description: Journal Netzwerk Frauen- und Geschlechterforschung NRW, vol. 2018, no. 43, p. 60
title: Hierarchy Identification for Automatically Generating Table-of-Contents
Creators: name: Erbs, Nicolai
name: Gurevych, Iryna
name: Zesch, Torsten
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2013
Subjects: subject: 004

description: A table-of-contents (TOC) provides a quick reference to a document‘s content and structure. We present the first study on identifying the hierarchical structure for automatically generating a TOC using only textual features instead of structural hints e.g. from HTML-tags. We create two new datasets to evaluate our approaches for hierarchy identification. We find that our algorithm performs on a level that is sufficient for a fully automated system. For documents without given segment titles, we extend out work by automatically generating segment titles. We make the datasets and our experimental framework publicly available in order to foster future research in TOC generation.
Effects of Escapin Intermediate Products (EIP-K) on Biofilms of Pseudomonas aeruginosa
Creators: name: Abdelaziz Ahmed, Marwa
Publisher: name: Georgia State University
Year: 2013

description: Escapin is an L-amino acid oxidase that produces antimicrobial metabolites collectively called ?Escapin Intermediate Products? (EIP-K). EIP-K and H2O2 together were previously shown to be bactericidal towards diverse planktonic bacteria. The present work investigates the ability of EIP-K and H2O2 to antagonize bacterial biofilms, using Pseudomonas aeruginosa as a model. The project had three aims: 1) determine the most effective concentrations of EIP-K and H2O2 necessary to break down existing P. aeruginosa biofilms, using a crystal violet assay; 2) examine the ability of EIP-K + H2O2 to inhibit biofilm formation, using triphenyl tetrazolium chloride dye; and 3) determine the effect of EIP-K + H2O2 on the viability, biomass and structure of biofilms cultivated in flow cells using confocal laser scanning microscopy (CLSM). Results showed that EIP-K + H2O2 significantly reduced biofilm biomass relative to controls and that the compounds are effective at nanomolar concentrations.
title: DKPro WSD: A Generalized UIMA-based Framework for Word Sense Disambiguation
Creators: name: Miller, Tristan
name: Erbs, Nicolai
name: Zorn, Hans-Peter
name: Zesch, Torsten
name: Gurevych, Iryna
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2013
Subjects: subject: 004

description: Implementations of word sense disambiguation (WSD) algorithms tend to be tied to a particular test corpus format and sense inventory. This makes it difficult to test their performance on new data sets, or to compare them against past algorithms implemented for different data sets. In this paper we present DKPro WSD, a freely licensed, general-purpose framework for WSD which is both modular and extensible. DKPro WSD abstracts the WSD process in such a way that test corpora, sense inventories, and algorithms can be freely swapped. Its UIMA-based architecture makes it easy to add support for new resources and algorithms. Related tasks such as word sense induction and entity linking are also supported.
The Developmental Regulation of Gene and Cellular Networks in Locomotion
Creators: name: Rupji, Manali
Publisher: name: Georgia State University
Year: 2013

description: A process such as locomotion requires a well-connected cellular network that is assembled by a gene network. Caenorhabditis elegans offers a tractable model system allowing integrative studies of gene and cellular networks. We have combined bioinformatics and cellular approaches to investigate such networks. The D motorneurons compose a cross ? inhibitory network essential for sinuous locomotion. Its terminal selector gene, unc-30 establishes the anatomical and neurochemical fates in these neurons. Three genes: unc-5, flp-11 and unc-104 are expressed in the D mns as well as other motorneuron classes. Using transcriptional reporters, we found that UNC-30 influenced the expression of each of these genes; however, in the most broadly expressed of the genes, unc-104, the impact of UNC-30 was less obvious. The bioinformatics analysis identified the cis-element for alr-1, in the promoters of all three genes. unc-30;alr-1 double mutant studies suggested that the two transcription factors act synergistically in regulating unc-104.
MIGNEX Background Paper D2.2: Qualitative Comparative Analysis for migration and development research
Creators: name: Czaika, Mathias
name: Godin, Marie
Publisher: name: Peace Research Institute Oslo
Year: 2019

description: Qualitative Comparative Analaysis (QCA) is a useful approach in identifying the causal configurations characterising the complex two-way relationship between migration and development. MIGNEX will highlight the potential contribution and limitations of QCA through reviewing and evaluating a scarce but rapidly growing literature on migration and development. This paper outlines some methodological features and basic principles for implementation.

Key Takeaways

QCA as a configurational method and methodology is designed to explore complex, multi-layered two-way relationships such as the linkages between migration and development.

QCA-based research on migration and development is still in its infancy and provides rich opportunities for more configurational research.

QCA has limitations and should therefore be triangulated with other qualitative and quantitative research methods.