cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ОЦЕНКА АКТИВНОСТИ МАТРИКСНЫХ МЕТАЛЛОПРОТЕИНАЗ ПРИ РЕМОДЕЛИРОВАНИИ СЕРДЦА У РЕБЕНКА С ДИСПЛАЗИЕЙ СОЕДИНИТЕЛЬНОЙ ТКАНИ (КЛИНИЧЕСКИЙ СЛУЧАЙ)
Creators: name: Ахрарова, Феруза
Publisher: name: Zenodo
Year: 2025

description: Дисплазия соединительной ткани (ДСТ) представляет собой группу наследственных заболеваний, характеризующихся нарушением структуры и функции соединительной ткани, что может затрагивать различные органы и системы, включая сердечно-сосудистую систему. Одним из основных молекулярных механизмов, способствующих развитию патологий при ДСТ, является дисбаланс в активности матриксных металлопротеиназ (ММП), которые отвечают за разрушение экстрацеллюлярного матрикса. Целью настоящего исследования является оценка активности ММП в плазме у ребенка с дисплазией соединительной ткани сердца и анализ роли метода желатиновой зимографии при исследовании ремоделирования миокарда. В работе представлен клинический случай девочки 13 лет, с дисплазией соединительной ткани сердца (ДСТС). Для оценки активности ММП использован метод желатиновой зимографии, который позволил выявить значительное повышение активности ММП-2 и ММП-9, что свидетельствует о патологических процессах деградации экстрацеллюлярного матрикса и нарушении ремоделирования миокарда. Полученные результаты подтверждают важность данного метода в диагностике заболеваний, связанных с ремоделированием сердца, и подчеркивают его потенциал в клинической практике для мониторинга прогрессирования заболеваний, ассоциированных с нарушениями соединительной ткани.
The Electron-Glass in samples approaching the Mesoscopic regime
Creators: name: Orlyanchik, V.
name: Ovadyahu, Z.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the dependence of the glassy properties of strongly localized indium-oxide films on the sample lateral dimensions. Characteristic mesoscopic effects such as reproducible conductance fluctuations (CF) are readily observable in gated structures for sample size smaller than 100 microns measured at 4K, and the relative amplitude of the CF decreases with the sample volume as does the flicker noise. By contrast, down to sample size of few microns, the non-equilibrium features that are attributed to the electron-glass are indistinguishable from those observed in macroscopic samples, and in particular, the relaxation dynamics is independent of sample size down to 2 microns. In addition, The usual features that characterize the electron-glass including slow-relaxation, memory effects, and full-aging behavior are all observed in the `mesoscopic' regime, and they appear to be independent of the conductance fluctuations.
description: 10 figures
title: Beyond Ritz-Galerkin: Finite element approximations on a manifold in the configuration space [Abstract]
Creators: name: Wackerfuß, Jens
name: Schröppel, Christian
Publisher: name: Universität Kassel
Year: 2016
Subjects: subject: 620
subject: Rotation
subject: Galerkin-Methode
subject: Finite-Elemente-Methode

description: Dies ist das Abstract. Der Vortrag selbst ist nicht in den Konferenz-Proceedings erschienen.
Model organism life extending therapeutics modulate diverse nodes in the drug-gene-microbe tripartite human longevity interactome
Creators: name: Salekeen, Rahagir
name: Lustgarten, Michael S.
name: Islam, Kazi Mohammed Didarul
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Computational Biology

description: Advances in antiaging drug/lead discovery in animal models constitute a large body of literature on novel senotherapeutics and geroprotectives. However, with little direct evidence or mechanism of action in humans—these drugs are utilized as nutraceuticals or repurposed supplements without proper testing directions, appropriate biomarkers, or consistent in-vivo models. In this study, we take previously identified drug candidates that have significant evidence of prolonging lifespan and promoting healthy aging in model organisms, and simulate them in human metabolic interactome networks. Screening for drug-likeness, toxicity, and KEGG network correlation scores, we generated a library of 285 safe and bioavailable compounds. We interrogated this library to present computational modeling-derived estimations of a tripartite interaction map of animal geroprotective compounds in the human molecular interactome extracted from longevity, senescence, and dietary restriction-associated genes. Our findings reflect previous studies in aging-associated metabolic disorders, and predict 25 best-connected drug interactors including Resveratrol, EGCG, Metformin, Trichostatin A, Caffeic Acid and Quercetin as direct modulators of lifespan and healthspan-associated pathways. We further clustered these compounds and the functionally enriched subnetworks therewith to identify longevity-exclusive, senescence-exclusive, pseudo-omniregulators and omniregulators within the set of interactome hub genes. Additionally, serum markers for drug-interactions, and interactions with potentially geroprotective gut microbial species distinguish the current study and present a holistic depiction of optimum gut microbial alteration by candidate drugs. These findings provide a systems level model of animal life-extending therapeutics in human systems, and act as precursors for expediting the ongoing global effort to find effective antiaging pharmacological interventions. Communicated by Ramaswamy H. Sarma
Sub-bandgap activated charges transfer in a graphene-MoS2-graphene heterostructure
Creators: name: Kumar, Sunil
name: Singh, Arvind
name: Nivedan, Anand
name: Kumar, Sandeep
name: Yun, Seok Joon
name: Lee, Young Hee
name: Tondusson, Marc
name: Degert, Jérôme
name: Oberle, Jean
name: Freysz, Eric
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Applied Physics (physics.app-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Monolayers of transition metal dichalcogenides are semiconducting materials which offer many prospects in optoelectronics. A monolayer of molybdenum disulfide (MoS2) has a direct bandgap of 1.88 eV. Hence, when excited with optical photon energies below its bandgap, no photocarriers are generated and a monolayer of MoS2 is not of much use in either photovoltaics or photodetection. Here, we demonstrate that large size MoS2 monolayer sandwiched between two graphene layers makes this heterostructure optically active well below the band gap of MoS2. An ultrafast optical pump-THz probe experiment reveals in real-time, transfer of carriers between graphene and MoS2 monolayer upon photoexcitation with photon energies down to 0.5 eV. It also helps to unravel an unprecedented enhancement in the broadband transient THz response of this tri-layer material system. We propose possible mechanism which can account for this phenomenon. Such specially designed heterostructures, which can be easily built around different transition metal dichalcogenide monolayers, will considerably broaden the scope for modern optoelectronic applications at THz bandwidth.
description: Manuscript with supplementary information
Phase transitions for the multifractal analysis of self-similar measures
Creators: name: Testud, Benoit
Publisher: name: arXiv
Year: 2006
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 28A80, 28A78

description: We study the multifractal analysis of a class of self-similar measures with overlaps. This class, for which we obtain explicit formulae for the L^q spectrum tau(q) as well as the singularity spectrum f(alpha), is sufficiently large to point out new phenomena concerning the multifractal structure of self-similar measures. We show, that unlike the classical quasi-Bernoulli case, the L^q spectrum can have an arbitrarely large number of non-differentiability points (phase transitions). These singularities occur only for the negative values of q and yield to measures that do not satisfy the multifractal formalism. The weak quasi-Bernoulli property is the key point of most of the arguments.
description: Article accept\'{e} pour publication dans Nonlinearity. Article en ligne \`{a} http://www.iop.org/EJ/journal/Non
Inuit place-names and main-land relationships, Pelly Bay, Northwest Territories
Creators: name: Goehring, Brian
Publisher: name: University of British Columbia
Year: 2010

description: The Inuit of Pelly Bay, N.W.T. have been among the last groups of native people in Canada to experience contact, and to settle in a permanent community. In this isolated settlement the Inuit culture, although changing and constantly adapting, remains strong. The traditional economy, based upon the harvesting of land-based resources, continues to be a vital part of the culture. The thesis examines the nature and extent of this man-land relationship, in the present-day context, and follows the on-the-land activities of all members of this community through one harvest year. Particular emphasis is paid to the nature of the location of such activities, and the methods by which Inuit navigate from place to place. The thesis details the location and translated meaning of 307 Inuktitut place names within the Pelly Bay land-use area, and demonstrates that an ordered and logical pattern of organisation of named physical features exists, a perception of landscape unique to the local region. The knowledge of these toponyms, combined with several supplemental techniques, forms a complete and functional system of navigation which continues to be used by the Inuit of Pelly Bay in their yearly cycle of on-the-land activities.
DFENet: A Novel Dimension Fusion Edge Guided Network for Brain MRI Segmentation
Creators: name: Basak, Hritam
name: Hussain, Rukhshanda
name: Rana, Ajay
Publisher: name: arXiv
Year: 2021
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: The rapid increment of morbidity of brain stroke in the last few years have been a driving force towards fast and accurate segmentation of stroke lesions from brain MRI images. With the recent development of deep-learning, computer-aided and segmentation methods of ischemic stroke lesions have been useful for clinicians in early diagnosis and treatment planning. However, most of these methods suffer from inaccurate and unreliable segmentation results because of their inability to capture sufficient contextual features from the MRI volumes. To meet these requirements, 3D convolutional neural networks have been proposed, which, however, suffer from huge computational requirements. To mitigate these problems, we propose a novel Dimension Fusion Edge-guided network (DFENet) that can meet both of these requirements by fusing the features of 2D and 3D CNNs. Unlike other methods, our proposed network uses a parallel partial decoder (PPD) module for aggregating and upsampling selected features, rich in important contextual information. Additionally, we use an edge-guidance and enhanced mixing loss for constantly supervising and improvising the learning process of the network. The proposed method is evaluated on publicly available Anatomical Tracings of Lesions After Stroke (ATLAS) dataset, resulting in mean DSC, IoU, Precision and Recall values of 0.5457, 0.4015, 0.6371, and 0.4969 respectively. The results, when compared to other state-of-the-art methods, outperforms them by a significant margin. Therefore, the proposed model is robust, accurate, superior to the existing methods, and can be relied upon for biomedical applications.
description: Submitted at SN Computer Science
Zorro – Vulpes vulpes Linnaeus, 1758
Creators: name: López-Martín, Josep Maria
name: Salvador Milla, Alfredo
Publisher: name: Salvador Milla, Alfredo
Year: 2017

description: Mamíferos - Orden Carnivora - Familia Canidae en la Enciclopedia Virtual de Vertebrados Españoles, http://www.vertebradosibericos.org/. Versiones anteriores: 10-06-2010
description: A comprehensive review of the natural history of the Red Fox Vulpes vulpes in Spain.
Density functional study of the variants of inter-Coulombic decay resonances in the photoionization of Cl@C60
Creators: name: De, Ruma
name: Ali, Esam
name: Manson, Steven T.
name: Chakraborty, Himadri S.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: Atomic Physics (physics.atom-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Inter-Coulombic decay (ICD) resonances in the photoionization of Cl@C60 endofullerene molecule are calculated using a perturbative density functional theory (DFT) method. This is the first ICD study of an open shell atom in a fullerene cage. Three classes of resonances are probed: (i) Cl inner vacancies decaying through C60 outer continua, (ii) C60 inner vacancies decaying through Cl outer continua, and (iii) inner vacancies of either system decaying through the continua of Cl-C60 hybrid levels, the hybrid Auger-ICD resonances. Comparisons with Ar@C60 results reveal that the properties of hybrid Auger-ICD resonances are affected by the extent of level hybridization.
description: 12 pages, 4 figures, Under journal review
Desmán ibérico – Galemys pyrenaicus (E. Geoffory, 1811)
Creators: name: Nores, Carlos
name: Salvador Milla, Alfredo
Publisher: name: Salvador Milla, Alfredo
Year: 2017

description: Mamíferos - Orden Insectivora - Familia Talpidae en la Enciclopedia Virtual de Vertebrados Españoles, http://www.vertebradosibericos.org/. Versiones anteriores: 5-07-2007; 31-03-2008; 4-04-2008; 19-11-2012
description: A comprehensive review of the natural history of the Pyrenean desman Galemys pyrenaicus in Spain.
title: Reality and methaphor at the core of architecture
Creators: name: da Conceição dos Santos, Joaquim Marcelino
Publisher: name: As fórmulas na arquitectura
Year: 2020

description: As fórmulas na arquitectura / 4.º Seminário Internacional de Arquitectura e Matemática ; coordenação de Fátima Silva, Elsa Negas, Rui Seco. - Lisboa : Universidade Lusíada, 2020. - P. 111-125.
Parameters of the crystalline undulator and its radiation for particular experimental conditions
Creators: name: Korol, A. V.
name: Solov'yov, A. V.
name: Greiner, Walter
name: .
name: .
Publisher: name: arXiv
Year: 2006
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: We report the results of theoretical and numerical analysis of the crystalline undulators planned to be used in the experiments which are the part of the ongoing PECU project [1]. The goal of such an analysis was to define the parameters (different from those pre-set by the experimental setup) of the undulators which ensure the highest yield of photons of specified energies. The calculations were performed for 0.6 and 10 GeV positrons channeling through periodically bent Si and Si$_{1-x}$Ge$_x$ crystals.
description: 13 pages, 8 figures, submitted to SPIE
Finite Gluon Fusion Amplitude in the Gauge-Higgs Unification
Creators: name: Maru, Nobuhito
Publisher: name: arXiv
Year: 2008
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We show that the gluon fusion amplitude in the gauge-Higgs unification scenario is finite in any dimension regardless of its nonrenormalizability. This result is supported by the fact that the local operator describing the gluon fusion process is forbidden by the higher dimensional gauge invariance. We explicitly calculate the gluon fusion amplitude in an arbitrary dimensional gauge-Higgs unification model and indeed obtain the finite result.
description: 15 pages, final version to appear in MPLA
Culebrera europea – Circaetus gallicus (Gmelin, 1788)
Creators: name: Ontiveros, Diego
name: Salvador Milla, Alfredo
Publisher: name: CSIC - Museo Nacional de Ciencias Naturales (MNCN)
Year: 2016
Subjects: subject: Description
subject: Size
subject: Variation
subject: Distribution
subject: Habitat
subject: Abundance
subject: Status
subject: Threats
subject: Diet
subject: Reproduction
subject: FOS: Medical biotechnology
subject: Demography
subject: FOS: Sociology
subject: Interactions
subject: Predators
subject: Parasites
subject: Pathogens
subject: Activity
subject: Home range
subject: Bibliography

description: Aves - Orden Falconiformes - Familia Accipitridae en la Enciclopedia Virtual de Vertebrados Españoles, http://www.vertebradosibericos.org/. Versiones anteriores: 2-06-2005; 6-03-2008; 30-06-2011; 6-08-2011; 14-02-2014; 22-07-2015
description: Natural history of the short-toed eagle Circaetus gallicus in Spain.
Hydrodynamics of a Semipermeable Vesicle Under Flow and Confinement
Creators: name: Quaife, Bryan
name: Gannon, Ashley
name: Young, Y. -N.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Lipid bilayer membranes have a native (albeit small) permeability for water molecules. Under an external load, provided that the bilayer structure stays intact and does not suffer from poration or rupture, a lipid membrane deforms and its water influx/efflux is often assumed negligible in the absence of osmolarity. In this work we use boundary integral simulations to investigate the effects of water permeability on the vesicle hydrodynamics due to a mechanical load, such as the viscous stress from an external flow deforming a vesicle membrane in free space or pushing it through a confinement. Incorporating the membrane permeability into the framework of Helfrich free energy for an inextensible, elastic membrane as a model for a semipermeable vesicle, we illustrate that, in the absence of an osmotic stress gradient, the semipermeable vesicle is affected by water influx/efflux over a sufficiently long time or under a strong confinement. Our simulations quantify the conditions for water permeation to be negligible in terms of the time scales, flow strength, and confinement. These results shed light on how microfluidic confinement can be utilized to estimate membrane permeability.
Attraction time for strongly reinforced walks
Creators: name: Cotar, Codina
name: Limic, Vlada
Publisher: name: arXiv
Year: 2006
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60G50, 60J10, 60K35 (Primary)

description: We consider a class of strongly edge-reinforced random walks, where the corresponding reinforcement weight function is nondecreasing. It is known, from Limic and Tarrès [Ann. Probab. (2007), to appear], that the attracting edge emerges with probability 1 whenever the underlying graph is locally bounded. We study the asymptotic behavior of the tail distribution of the (random) time of attraction. In particular, we obtain exact (up to a multiplicative constant) asymptotics if the underlying graph has two edges. Next, we show some extensions in the setting of finite graphs, and infinite graphs with bounded degree. As a corollary, we obtain the fact that if the reinforcement weight has the form $w(k)=k^ρ$, $ρ>1$, then (universally over finite graphs) the expected time to attraction is infinite if and only if $ρ\leq1+\frac{1+\sqrt{5}}{2}$.
description: Published in at http://dx.doi.org/10.1214/08-AAP564 the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Políticas públicas para a educação superior no Brasil
Creators: name: Mota Júnior, Antônio de Macêdo
Publisher: name: figshare
Year: 2021
Subjects: subject: 160506 Education Policy
subject: FOS: Political science

description: O presente trabalho aborda o tema das políticas públicas educacionais, com ênfase na educação superior do Brasil. Este estudo exploratório, bibliográfico e documental tem como objetivo caracterizar a política pública de educação superior no Brasil, realizando uma revisão bibliográfica sobre política e políticas públicas, bem como caracterizando os marcos normativos da política educacional brasileira e suas implicações para a expansão da oferta de educação superior no país. Os resultados evidenciam que as políticas educacionais são políticas públicas de cunho social, que visam à diminuição das desigualdades sociais existentes no país, no âmbito educacional. Demonstram ainda que a Constituição Federal de 1988 e a atual Lei de Diretrizes e Bases da Educação Nacional (LDB) são instrumentos balizadores da política educacional no Brasil, tendo o Plano Nacional de Educação 2014-2024, como o atual e principal documento para o desenvolvimento da educação nacional. Além disso, em relação à expansão da oferta da educação superior, houve significativa evolução, principalmente pela liberalização e incentivo à iniciativa privada, bem como por ações do governo federal, como o Programa REUNI.
Dressing the Giant Magnon
Creators: name: Spradlin, Marcus
name: Volovich, Anastasia
Publisher: name: arXiv
Year: 2006
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We apply the dressing method to construct new classical string solutions describing various scattering and bound states of magnons. These solutions carry one, two or three SO(6) charges and correspond to multi-soliton configurations in the generalized sine-Gordon models.
description: 22 pages, harvmac, v3: interpretation corrected in section 4.4
Additional file 1 of Research article network analysis of polymicrobial chronic wound infections in Masanga, Sierra Leone
Creators: name: Sandmann, Sarah
name: Nunes, Jonathan Vas
name: Grobusch, Martin P.
name: Sesay, Maxwell
name: Kriegel, Martin A.
name: Varghese, Julian
name: Schaumburg, Frieder
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Ecology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplementary Material 1
Dimensional reduction of cavities with axial symmetry: A complete analysis of when an optical fiber is approximately one-dimensional
Creators: name: Grimmer, Daniel
name: Lopp, Richard
name: Martín-Martínez, Eduardo
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Intuition dictates that a very long, very thin cavity (e.g., a fiber optic cable) could perhaps be modeled as an approximately one dimensional system. In this paper we rigorously explore the validity of such intuition from the perspective of a localized probe coupling to a quantum field inside a cavity (e.g., an atom or an Unruh-DeWitt particle detector in a fiber optic cable). To do so, we introduce the notion of subfield decomposition in which a $D+1$ dimensional quantum field in an axially-symmetric cavity can be reduced to an infinite collection of uncoupled, massive $1+1$ dimensional fields. We show that the ability to approximate a higher-dimensional scenario by a $1+1$ dimensional model is equivalent to making a certain change of the probe's shape in the higher-dimensional space. The approximation is justified whenever this change of shape is "small enough". In this light, we identify the dynamically relevant norm by which the magnitude of these changes in probe shape ought to be judged. Finally, we explore this approximation in particular setups corresponding to quantum optics and superconducting circuits.
description: 14 Pages, 4 Figures. RevTeX 4.1
Política pública de formação de professores por meio da educação a distância (EAD)
Creators: name: Mota Júnior, Antônio de Macêdo
name: Moura, Patrícia Almeida
name: Araújo, Kátia Soane Santos
Publisher: name: figshare
Year: 2021
Subjects: subject: 130304 Educational Administration, Management and Leadership
subject: FOS: Educational sciences
subject: 160506 Education Policy
subject: FOS: Political science

description: Este artigo tem como tema as políticas públicas no processo de formação de professores, por meio da educação a distância (EAD). Para desenvolver esse estudo exploratório, utilizamos metodologicamente a pesquisa bibliográfica e documental. No decorrer do texto, procuramos fazer uma reflexão sobre esse processo formativo, por meio das políticas públicas, através do olhar de autores como: Cavalcanti (2012), Souza (2006), Saviani (2009), Gatti (2011), entre outros. A princípio, situamos o leitor sobre o conceito de políticas públicas e seu envolvimento no processo de formação de professores no ensino superior. Em seguida, fazemos uma abordagem sobre o processo de formação de professores, destacando que, somente após a promulgação da Constituição Federal de 1988 e publicação da Lei de Diretrizes e Bases da Educação Nacional (LDB), Lei Nº 9.394/1996, é que se observa um processo de implantação da EAD na educação brasileira, regulamentado pelo Decreto Federal Nº 5.622/2005, que estabeleceu a modalidade nos diferentes níveis educacionais.
Quantum Monte Carlo simulations in the trimer basis: first-order transitions and thermal critical points in frustrated trilayer magnets
Creators: name: Weber, L.
name: Honecker, A.
name: Normand, B.
name: Corboz, P.
name: Mila, F.
name: Wessel, S.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The phase diagrams of highly frustrated quantum spin systems can exhibit first-order quantum phase transitions and thermal critical points even in the absence of any long-ranged magnetic order. However, all unbiased numerical techniques for investigating frustrated quantum magnets face significant challenges, and for generic quantum Monte Carlo methods the challenge is the sign problem. Here we report on a general quantum Monte Carlo approach with a loop-update scheme that operates in any basis, and we show that, with an appropriate choice of basis, it allows us to study a frustrated model of coupled spin-1/2 trimers: simulations of the trilayer Heisenberg antiferromagnet in the spin-trimer basis are sign-problem-free when the intertrimer couplings are fully frustrated. This model features a first-order quantum phase transition, from which a line of first-order transitions emerges at finite temperatures and terminates in a thermal critical point. The trimer unit cell hosts an internal degree of freedom that can be controlled to induce an extensive entropy jump at the quantum transition, which alters the shape of the first-order line. We explore the consequences for the thermal properties in the vicinity of the critical point, which include profound changes in the lines of maxima defined by the specific heat. Our findings reveal trimer quantum magnets as fundamental systems capturing in full the complex thermal physics of the strongly frustrated regime.
description: 27 pages, 10 figures, Resubmission to SciPost
MOESM8 of Mutation of 4-coumarate: coenzyme A ligase 1 gene affects lignin biosynthesis and increases the cell wall digestibility in maize brown midrib5 mutants
Creators: name: Xiong, Wangdan
name: Wu, Zhenying
name: Liu, Yuchen
name: Li, Yu
name: Su, Kunlong
name: Bai, Zetao
name: Guo, Siyi
name: Hu, Zhubing
name: Zhang, Zhiming
name: Bao, Yan
name: Sun, Juan
name: Yang, Guofeng
name: Fu, Chunxiang
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology
subject: Virology

description: Additional file 8: Fig. S4. Transcriptome analysis of bm5 mutant by microarray.
The impact of alternative ideology on landscape : the back-to-the-land movement in the Slocan Valley
Creators: name: Gower, John Gordon
Publisher: name: University of British Columbia
Year: 2010

description: Like many North American resource-based rural communities, the Slocan Valley in southeastern British Columbia experienced a decline in its population and economy during the first half of this century. However, in the late 1960s, mainly young, well-educated and often idealistic members of the back-to-the-land movement began to re-settle the area. The influx reached its peak in the mid 1970s, and at a diminished level, continues. Currently this group of recent settlers comprises approximately one-quarter of the valley's population of 5000. Drawing on data from participant observation in the area and personal interviews with members of this influx, this thesis first examines why and how these people came to settle in the Slocan. It finds that they moved for many different reasons: repelled by the "rat-race" and pollution of the cities, and the violent politics of the 1960's; or attracted by the prospects of a personally-meaningful and satisfying existence in the country-side. Whether driven by an individualistic or visionary quest, all subscribed to some extent to a back-to-the-land ideology which advocated a low-consumption, but highly diverse, lifestyle - close to nature and in touch with the land, independent politically and economically from the larger society, and in a community of like-minded rural neighbours. Secondly, the thesis traces the evolution of personal lifeways and the development of community life in the twenty years since the resettlement began. As the newcomers encountered difficulties living in the Slocan they made compromises. As a result, their lifestyles are no longer as clearly "alternative" and most have reentered the "system" to some degree. Increasingly though, their values have found expression in specific causes, issues or projects which have altered the course of evolution of the Slocan, and left a lasting legacy of concrete accomplishments and changed attitudes within the larger geographic community. The settlers’ impact has been particularly noticeable in issues regarding land and resource use, the diversification of the regional economy, and attempts to attain local political autonomy. Finally, the thesis attempts to assess the significance of the back-to-the-land movement to the Slocan, and then to society as a whole. The Slocan in the 1990s is at a bifurcation point, and must choose its destiny from a range of divergent, and often conflicting, alternatives. Whether the area pursues a sustainable path, in which the viability of the local community and integrity of the environment are protected and enhanced, depends largely on which of the two competing ideologies (industrial versus post-industrial) currently represented in the Slocan prevails. In this regard, the Valley is a microcosm of the broader society: the experiences there show where both the opportunities and impediments lie in our search for a truly sustainable society.
A partial $A_\infty$-structure on the cohomology of $C_n\times C_m$
Creators: name: Vejdemo-Johansson, Mikael
Publisher: name: arXiv
Year: 2007
Subjects: subject: K-Theory and Homology (math.KT)
subject: Algebraic Topology (math.AT)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 55P43 (Primary), 16E40 (Secondary)

description: Suppose k is a field of characteristic 2, and $n,m\geq 4$ powers of 2. Then the $A_\infty$-structure of the group cohomology algebras $H^*(C_n,k)$ and $(H^*(C_m,k)$ are well known. We give results characterizing an $A_\infty$-structure on $H^*(C_n\times C_m,k)$ including limits on non-vanishing low-arity operations and an infinite family of non-vanishing higher operations.
description: 11 pages, updated to official JHRS version.
Characterization of Low Emittance Electron Beams Generated by Transverse Laser Beam Shaping
Creators: name: Groß, Matthias
name: Aftab, Namra
name: Boonpornprasert, Prach
name: Chen, Ye Lining
name: Georgiev, Georgi
name: Good, James
name: Koschitzki, Christian
name: Krasilnikov, Mikhail
name: Li, Xiangkun
name: Lishilin, Osip
name: Loisch, Gregor
name: Melkumyan, David
name: Mohanty, Sandeep
name: Niemczyk, Raffael
name: Oppelt, Anne
name: Qian, Houjun
name: Shu, Guan
name: Stephan, Frank
name: Vashchenko, Grygorii
name: Will, Ingo
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2021
Subjects: Accelerator Physics
MC2: Photon Sources and Electron Accelerators

description: 12th International Particle Accelerator Conference, IPAC'21, Campinas, Brazil, 24 May 2021 - 28 May 2021; doi:10.18429/JACOW-IPAC2021-WEPAB040
description: Linac based X-ray free electron laser demand a high beam quality from the electron source, therefore RF photoinjectors are used to generate the electron bunches for state of the art beam brightness. One important figure of merit for these injectors is the transverse emittance of the generated electron beam, which can be minimized by shaping the photocathode laser pulses. Best performance can be achieved with ellipsoidal laser pulses, but 3D shaping is technically challenging. Typically, a quasi-uniform transverse laser profile is truncated from the Gaussian profile generated by the laser with an aperture to reduce the transverse nonlinear space charge forces. This is investigated in detail by optimizing the laser transverse profile at the Photoinjector Test facility at DESY in Zeuthen (PITZ), where photoinjector R is conducted for the E-XFEL and FLASH free electron lasers at DESY in Hamburg. In this contribution we present experimental results at high acceleration gradients (up to 60 MV/m) for both 250 pC and 500 pC. For a bunch charge of 500 pC an emittance reduction of about 30% compared to the commonly used transverse flat-top laser distribution was achieved.
Calibration of flux crosstalk in large-scale flux-tunable superconducting quantum circuits
Creators: name: Dai, X.
name: Tennant, D. M.
name: Trappen, R.
name: Martinez, A. J.
name: Melanson, D.
name: Yurtalan, M. A.
name: Tang, Y.
name: Novikov, S.
name: Grover, J. A.
name: Disseler, S. M.
name: Basham, J. I.
name: Das, R.
name: Kim, D. K.
name: Melville, A. J.
name: Niedzielski, B. M.
name: Weber, S. J.
name: Yoder, J. L.
name: Lidar, D. A.
name: Lupascu, A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Magnetic flux tunability is an essential feature in most approaches to quantum computing based on superconducting qubits. Independent control of the fluxes in multiple loops is hampered by crosstalk. Calibrating flux crosstalk becomes a challenging task when the circuit elements interact strongly. We present a novel approach to flux crosstalk calibration, which is circuit model independent and relies on an iterative process to gradually improve calibration accuracy. This method allows us to reduce errors due to the inductive coupling between loops. The calibration procedure is automated and implemented on devices consisting of tunable flux qubits and couplers with up to 27 control loops. We devise a method to characterize the calibration error, which is used to show that the errors of the measured crosstalk coefficients are all below 0.17%.
description: 22 pages, 15 figures
Deliverable 3.5 - New Vaccines
Creators: name: Didlick, Susan
name: Swann, Amanda
name: Pike, Hannah
name: Topham, Tracey
name: McKee, Callum
name: Cavill, Laura
name: Smith, Patrick
Publisher: name: Zenodo
Year: 2020

description: The aim of this Deliverable is to investigate and improve the current vaccines for European sea bass (BSS) and gilthead sea bream (SBG). This remit included collection and typing of the current pathogens in the field; to make sure any pathogenic strains of Noda virus, Photobacterium damsela subsp. piscicida and Vibrio anguillarum were included in the vaccine; to improve quality and efficacy of the new vaccines including optimisation of vaccine production methods; to produce new range of vaccines to protect fish for all stages of the lifecycle with improved protection and duration of immunity. The aim of the vaccines produced in PerformFISH is to improve on the current efficacy and include novel vaccines to the portfolio of available products. Aquaxprs has prepared the only experimental triple VNN, Vibrio, & Pasteurella vaccine and the only VNN immersion vaccine technologies available and with the validation field trials scheduled in PerformFISH project, these will hopefully be commercialised by 2021. It is important to continually monitor the situation in the field and make improvements to the vaccines if required. It is also important to access our vaccines performance against the competition. During the development of this task, it was evident that new developments in both strain characterisation & typing, diagnostic testing and vaccine components were available outside the consortium. In order to take advantage of these new developments, Aquaxprs financed certain areas of the vaccine development on its means. These complementary results are included in this Deliverable to draw a more complete picture of the endeavour to deliver improved vaccines for the MMFF sector.
QCD at the Dawn of the LHC Era
Creators: name: Kosower, David A.
Publisher: name: arXiv
Year: 2006
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Precision computations of QCD and QCD+electroweak emission scattering processes will play an important role in understanding experimental data from the LHC, and thereby in uncovering new physics beyond the Standard Model. Recent years have seen substantial progress in expanding our ability to perform and implement such calculations. I discuss several different topics: the resolution of seeming discrepancies between heavy-quark predictions and measurements; the ongoing program of next-to-next-to-leading order calculations; and also progress in merging the parton-shower and matrix-element calculations. I will also outline some of the techniques emerging from twistor-space string theory and its intellectual progeny.
description: Plenary talk given at PANIC '05, Santa Fe, New Mexico, Oct 24-28, 2005
Modeling the Magnetic Field of the LCLS-I Undulator for THz@PITZ
Creators: name: Krasilnikov, Mikhail
name: Brachmann, Axel
name: Li, Xiangkun
name: Lueangaramwong, Anusorn
name: Mueller, Frieder
name: Nuhn, Heinz-Dieter
name: Stephan, Frank
name: Tischer, Markus
name: Vagin, Pavel
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2021
Subjects: Accelerator Physics
MC2: Photon Sources and Electron Accelerators

description: the 12th International Particle Accelerator Conference, IPAC'21, Campinas, Brazil, 24 May 2021 - 28 May 2021; doi:10.18429/JACOW-IPAC2021-THPAB049
description: An accelerator-based THz source for pump-probe experiments at the European XFEL is under development at the Photo Injector Test Facility at DESY in Zeuthen (PITZ). For the proof-of-principle experiments an LCLS-I undulator is planned to be installed downstream of the PITZ accelerator. The fields of the undulator module 26 have been re-measured at DESY in Hamburg and the results are consistent with earlier SLAC measurements. A model for 3D field reconstruction based on the undulator magnetic measurements has been developed. It includes also a horizontal gradient of the vertical field. Tracking of the 17 MeV/c beam has revealed that the transverse gradient will lead to a significant off-axis trajectory in the horizontal plane. This offset has to be corrected with a steering coil, the design of which is also presented. The performance of the THz generation with the correction coil is discussed as well.
Closing up the cluster tension?
Creators: name: Blanchard, Alain
name: Ilić, Stéphane
Publisher: name: arXiv
Year: 2021
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The excellent measurements of the cosmic microwave background (CMB) fluctuations by Planck allow us to tightly constrain the amplitude of matter fluctuations at redshift $\sim 1100$ in the $Λ$-cold dark matter ($Λ$CDM) model. This amplitude can be extrapolated to the present epoch, yielding constraints on the value of the $σ_8$ parameter. On the other hand, the abundance of Sunyaev-Zeldovich (SZ) clusters detected by Planck, with masses inferred using a hydrostatic equilibrium assumption, leads to a significantly lower value of the same parameter. This discrepancy is often dubbed the $σ_8$ tension in the literature and is sometimes regarded as a possible sign of new physics. Here, we examine a direct determination of $σ_8$ at the present epoch in $Λ$CDM, and thereby the cluster mass calibrations using cosmological data at low redshift, namely the measurements of $fσ_8$ from the analysis of the completed Sloan Digital Sky Survey (SDSS). We combined redshift-space distortion measurements with Planck CMB constraints, X-ray, and SZ cluster counts within the $Λ$CDM framework, but leaving the present-day amplitude of matter fluctuations as an independent parameter (i.e. no extrapolation is made from high-redshift CMB constraints). The calibration of X-ray and SZ masses are left as free parameters throughout the whole analysis. Our study yields tight constraints on the aforementioned calibrations, with values entirely consistent with results obtained from the full combination of CMB and cluster data only. Such an agreement suggests an absence of tension in the $Λ$CDM model between CMB-based estimates of $σ_8$ and constraints from low-redshift on $fσ_8$; however, it also indicates tension with the standard calibration of clusters masses.
description: 4 pages, 1 figure, accepted in A&A, v2: replaced to match the accepted version
Matching of a Space-Charge Dominated Beam into the Undulator of the THz SASE FEL at PITZ
Creators: name: Li, Xiangkun
name: Aboulbanine, Zakaria
name: Adhikari, Gowri
name: Aftab, Namra
name: Amirkhanyan, Zohrab
name: Boonpornprasert, Prach
name: Castro Carballo, Maria Elena
name: Chaisueb, Natthawut
name: Georgiev, Georgi
name: Good, James
name: Groß, Matthias
name: Koschitzki, Christian
name: Krasilnikov, Mikhail
name: Lishilin, Osip
name: Lueangaramwong, Anusorn
name: Melkumyan, David
name: Niemczyk, Raffael
name: Oppelt, Anne
name: Qian, Houjun
name: Shu, Guan
name: Stephan, Frank
name: Vashchenko, Grygorii
name: Weilbach, Tobias
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2021
Subjects: Accelerator Physics
MC5: Beam Dynamics and EM Fields

description: 12th International Particle Accelerator Conference, IPAC'21, Campinas, Brazil, 24 May 2021 - 28 May 2021; doi:10.18429/JACOW-IPAC2021-WEPAB257
description: The Photo Injector Test facility at DESY in Zeuthen (PITZ) is developing a THz SASE FEL as a prototype high repetition rate accelerator-based source for the THz-pumped, X-ray-probed experiments at the European XFEL. For the generation of THz pulses of mJ-level energy from SASE, an electron beam with a high charge (up to 4 nC) and high peak current (~200 A) will be injected into an LCLS-I undulator, which is currently being installed at the end of the photo-injector. The narrow vacuum chamber (11x5 mm) between the magnetic poles and the strong vertical focusing from the undulator, as well as the lack of beam diagnostics, have made it a challenge to match the space-charge dominated beam into the undulator without beam loss during the following transport. In this paper, boundary conditions of a matched electron beam will be discussed and the simulation and experimental study on our matching strategy will be presented.
QCD transition at the physical point, and its scaling window from twisted mass Wilson fermions
Creators: name: Kotov, A. Yu.
name: Lombardo, M. P.
name: Trunin, A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the scaling properties of the finite temperature QCD phase transition, for light quark masses ranging from the heavy quark regime to their physical values. The lattice results are obtained in the fixed scale approach from simulations of $N_f=2+1+1$ flavours of Wilson fermions at maximal twist. We identify an order parameter free from the the linear contributions in mass due to additive renormalization and regular terms in the Equation of State, which proves useful for the assessment of the hypothesized universal behaviour. We find compatibility with the 3D $O(4)$ universality class for the physical pion mass and temperatures $120$ MeV $ \lesssim T \lesssim 300$ MeV. We discuss violation of scaling at larger masses and a possible cross-over to mean field behaviour. The chiral extrapolation $T_0 = 134^{+6}_{-4}$ MeV of the pseudocritical temperature is robust against predictions of different universality classes and consistent with its estimate from the $O(4)$ Equation of State for the physical pion mass.
description: 10 pages, 10 figures, 4 tables; version accepted for publication in PLB
The impact of a telephone contact program on physical and psychological functioning : level of pain and perceived social support among elderly females with arthritis
Creators: name: Taylor, Gregory
Publisher: name: University of British Columbia
Year: 2010

description: Having identified the need to provide services to elderly, homebound people with arthritis, the Social Work Department at the Vancouver Arthritis Centre initiated an Arthritis Telephone Contact Program in Autumn, 1989. The purpose of this study was to investigate whether or not a weekly telephone call from volunteers would impact positively on subjects' physical and psychological functioning, level of pain and perceived level of social support. The 11 subjects in this study were elderly, Caucasian women identified by health care professionals as being socially isolated due, in part, to the limits placed on them by either osteoarthritis or rheumatoid arthritis. The one-group pretest-posttest research design was employed for this study. Quantitative measures used were the Arthritis Impact Measurement Scales (AIMS) and the Perceived Social Support From Friends and From Family Scale (PSS-Fr & Fa). Interviews of subjects were conducted in order to describe the efficacy of the Telephone Contact Program from more than one perspective. Over 16 weeks, paired t-test found that the physical functioning of subjects had improved significantly. It was noted that there was a trend towards improved health status for the experimental group in that seven out of the eight subscales of AIMS measured improvement, while one subscale showed no change. Contrary to prediction, perception of social support from family members decreased significantly, as measured by the PSS-Fa scale. Pearson correlation coefficients found no association between changes in perception of social support and changes in health status. Interview data suggests that callers were perceived as sources of social support. Specifically, callers seemed to provide participants with emotional support, informational support, and positive social interaction. Overall, the data suggested that the Telephone Contact Program had the capability to evoke small, but clinically meaningfully improvements in the health status of elderly women with arthritis. Further investigation into the use of telephone contact programs as a minimal intervention is advised.