cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Mining multi-item drug adverse effect associations in spontaneous reporting systems
Creators: name: Harpaz, Rave
name: Chase, Herbert
name: Friedman, Carol
Publisher: name: Columbia University
Year: 2010
Subjects: subject: Bioinformatics
subject: FOS: Computer and information sciences

description: Multi-item adverse drug event (ADE) associations are associations relating multiple drugs to possibly multiple adverse events. The current standard in pharmacovigilance is bivariate association analysis, where each single drug-adverse effect combination is studied separately. The importance and difficulty in the detection of multi-item ADE associations was noted in several prominent pharmacovigilance studies. In this paper we examine the application of a well established data mining method known as association rule mining, which we tailored to the above problem, and demonstrate its value. The method was applied to the FDAs spontaneous adverse event reporting system (AERS) with minimal restrictions and expectations on its output, an experiment that has not been previously done on the scale and generality proposed in this work. Based on a set of 162,744 reports of suspected ADEs reported to AERS and published in the year 2008, our method identified 1167 multi-item ADE associations. A taxonomy that characterizes the associations was developed based on a representative sample. A significant number (67% of the total) of potential multi-item ADE associations identified were characterized and clinically validated by a domain expert as previously recognized ADE associations. Several potentially novel ADEs were also identified. A smaller proportion (4%) of associations were characterized and validated as known drug-drug interactions. Our findings demonstrate that multi-item ADEs are present and can be extracted from the FDA’s adverse effect reporting system using our methodology, suggesting that our method is a valid approach for the initial identification of multi-item ADEs. The study also revealed several limitations and challenges that can be attributed to both the method and quality of data.
Sonnenfleckenzeichnung Nr. 35.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.02.1990, 08:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 9.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.01.1990, 08:45, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Spectroscopy of the enigmatic short-period cataclysmic variable IR Com in an extended low state
Creators: name: Manser, C. J.
name: Gaensicke, B. T.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report the occurrence of a deep low state in the eclipsing short-period cataclysmic variable IR Com, lasting more than two years. Spectroscopy obtained in this state shows the system as a detached white dwarf plus low-mass companion, indicating that accretion has practically ceased. The spectral type of the companion derived from the SDSS spectrum is M6-7, somewhat later than expected for the orbital period of IR Com. Its radial velocity amplitude, K_2=419.6+-3.4 km/s, together with the inclination of 75-90deg implies 0.8Msun
description: Revised version, MNRAS Letters in press
Microlensing towards the SMC: a new analysis of OGLE and EROS results
Creators: name: Novati, S. Calchi
name: Mirzoyan, S.
name: Jetzer, Ph.
name: Scarpetta, G.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present a new analysis of the results of the EROS-2, OGLE-II, and OGLE-III microlensing campaigns towards the Small Magellanic Cloud (SMC). Through a statistical analysis we address the issue of the \emph{nature} of the reported microlensing candidate events, whether to be attributed to lenses belonging to known population (the SMC luminous components or the Milky Way disc, to which we broadly refer to as "self lensing") or to the would be population of dark matter compact halo objects (MACHOs). To this purpose, we present profiles of the optical depth and, comparing to the observed quantities, we carry out analyses of the events position and duration. Finally, we evaluate and study the microlensing rate. Overall, we consider five reported microlensing events towards the SMC (one by EROS and four by OGLE). The analysis shows that in terms of number of events the expected self lensing signal may indeed explain the observed rate. However, the characteristics of the events, spatial distribution and duration (and for one event, the projected velocity) rather suggest a non-self lensing origin for a few of them. In particular we evaluate, through a likelihood analysis, the resulting upper limit for the halo mass fraction in form of MACHOs given the expected self-lensing and MACHO lensing signal. At 95% CL, the tighter upper limit, about 10%, is found for MACHO mass of $10^{-2} \mathrm{M}_\odot$, upper limit that reduces to above 20% for $0.5 \mathrm{M}_\odot$ MACHOs.
description: MNRAS in press, 17 pages, 7 figures, 5 tables
Biblia latina (Fragmente der B 36; [um 1460]
Creators: name: (:Unav)
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2011

description: Provenienz: Die Herkunft des Fragments ist unbekannt; es bildete bis 1908 den Umschlag von 2° Jus. 98.
Using the s-Ensemble to Probe Glasses Formed by Cooling and Aging
Creators: name: Keys, Aaron S.
name: Chandler, David
name: Garrahan, Juan P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: From length scale distributions characterizing frozen amorphous domains, we relate the s-ensemble method with standard cooling and aging protocols for forming glass. We show that in a general class of models, where space-time scaling is in harmony with that of experiment, the domain size distributions obtained with the s-ensemble are identical to those obtained through cooling or aging, but the computational effort for applying the s-ensemble is generally many orders of magnitude smaller than that of straightforward numerical simulation of cooling or aging.
description: 6 pages, 4 figures
Treatment of mechanically-induced vasospasm of the carotid artery in a primate using intra-arterial verapamil: a technical case report
Creators: name: Coon, Alexander
name: Colby, Geoffrey
name: Mack, William
name: Feng, Lei
name: Meyers, Philip M.
name: Sander Connolly Jr., E.
Publisher: name: Columbia University
Year: 2004
Subjects: subject: Surgery
subject: Neurosciences
subject: FOS: Clinical medicine

description: Despite improvements in the safety and efficacy of endovascular procedures, considerable morbidity may still be attributed to vasospasm. Vasospasm has proven amenable to pharmacological intervention such as nitrates, intravenous calcium channel blockers (CCBs), and intra-arterial papaverine, particularly in small vessels. However, few studies have focused on medium to large vessel spasm. Here we report the use of an intra-arterial CCB, verapamil, to treat flow-limiting mechanically-induced spasm of the common carotid artery (CCA) in a primate. We believe this to be the first such report of its kind. As part of a study assessing the placement feasibility and safety of a catheter capable of delivering intra-arterial cerebroprotective therapy, a female 16 kg baboon prophylaxed with intravenous nitroglycerin underwent transfemoral CCA catheterization with a metallic 6-Fr catheter without signs of acute spasm. The protocol dictated that the catheter remain in the CCA for 12 hours. Upon completion of the protocol, arteriography revealed a marked decrease in CCA size (mean cross-sectional area reduction = 31.6 ± 1.9%) localized along the catheter length. Intra-arterial verapamil (2 mg/2cc) was injected and arteriography was performed 10 minutes later. Image analysis at 6 points along the CCA revealed a 21.0 ± 1.7% mean increase in vessel diameter along the length of the catheter corresponding to a 46.7 ± 4.0% mean increase in cross-sectional area. Mean systemic blood pressure did not deviate more than 10 mm Hg during the procedure. Intraluminal CCBs like verapamil may constitute an effective endovascular treatment for mechanically-induced vasospasm in medium to large-sized vessels such as the CCA.
The quark-hadron thermodynamics in magnetic field
Creators: name: Orlovsky, V. D.
name: Simonov, Yu. A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Nonperturbative treatment of quark-hadron transition at nonzero temperature T and chemical potential mu in the framework of Field Correlator Method is generalized to the case of nonzero magnetic field B. A compact form of the quark pressure for arbitrary B, mu, T is derived. As a result the transition temperature is found as a function of B and mu, which depends on only parameters: vacuum gluonic condensate G_2 and the field correlator D_1^E(x), which defines the Polyakov loops and it is known both analytically and on the lattice. A moderate (25%) decrease of T_c(mu=0) for eB changing from zero to 1 GeV^2 is found. A sequence of transition curves in the (mu, T) plane is obtained for B in the same interval, monotonically decreasing in scale for growing B.
description: 24 pages, 2 figures, misprints corrected, references added
Serendipitous detection of an overdensity of Herschel-SPIRE 250 micron sources south of MRC1138-26
Creators: name: Valtchanov, Ivan
name: Altieri, B.
name: Berta, S.
name: Chapin, E.
name: Coia, D.
name: Conversi, L.
name: Dannerbauer, H.
name: Domínguez-Sánchez, H.
name: Rawle, T. D.
name: Sánchez-Portal, M.
name: Santos, J. S.
name: Temporin, S.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report the serendipitous detection of a significant overdensity of Herschel-SPIRE 250 micron sources in the vicinity of MRC1138-26. We use an adaptive kernel density estimate to quantify the significance, including a comparison with other fields. The overdensity has a size of ~3.5-4' and stands out at ~5sigma with respect to the background estimate. No features with similar significance were found in four extragalactic control fields: GOODS-North, Lockman, COSMOS and UDS. The chance of having a similar overdensity in a field with the same number but randomly distributed sources is less than 2%. The clump is also visible as a low surface brightness feature in the Planck 857 GHz map. We detect 76 sources at 250 micron (with a signal-to-noise ratio greater than 3), in a region of 4' radius; 43 of those are above a flux density limit of 20 mJy. This is a factor of 3.6 in excess over the average in the four control fields, considering only the sources above 20 mJy. We also find an excess in the number counts of sources with 250 micron flux densities between 30 and 40 mJy, compared to deep extragalactic blank-field number counts. Assuming a fixed dust temperature (30 K) and emissivity (beta=1.5) a crude, blackbody-derived redshift distribution, zBB, of the detected sources is significantly different from the distributions in the control fields and exhibits a significant peak at zBB ~ 1.5, although the actual peak redshift is highly degenerate with the temperature. We tentatively suggest, based on zBB and the similar S250/S350 colours of the sources within the peak, that a significant fraction of the sources in the clump may be at a similar redshift. Since the overdensity lies ~7' south of the z=2.16 Spiderweb protocluster MRC1138-26, an intriguing possibility (that is presently unverifiable given the data in hand) is that it lies within the same large-scale structure.(abridged)
description: 10 pages, 8 figures, accepted for publication in MNRAS
Asking the right questions: developing evidence-based strategies for treating HIV in women and children
Creators: name: Ronney, James
name: Wood, Robin
name: Heidari, Shirin
name: Cahn, Pedro
name: Christie, Celia D.C.
name: Dintruff, Robert
name: Distel, Manuel
name: Hankins, Catherine
name: Hellman, Nicholas
name: Katabira, Elly
name: Lehrman, Sandra
name: Montaner, Julio
name: Purdon, Scott
name: Karim, Quarraisha Abdool
name: Banegura, Anchilla
Publisher: name: Columbia University
Year: 2011
Subjects: Epidemiology
Medical sciences

description: In July 2010, the World Health Organization (WHO) issued formal revisions of its guidelines on the use of highly active antiretroviral therapy for HIV. The new guidelines greatly expand eligibility for treatment of adults and children, as well as for pregnant women seeking prophylaxis for vertical HIV transmission. WHO's new recommendations bring the guidelines closer to practices in developed countries, and its shift to earlier treatment alone will increase the number of treatment-eligible people by 50% or more.

Scaling up access to HIV treatment is revealing important gaps in our understanding of how best to provide for all those in need. This knowledge gap is especially significant in developing countries, where women and children comprise a majority of those living with HIV infection. Given the magnitude and significance of these populations, the International AIDS Society, through its Industry Liaison Forum, prioritized HIV treatment and prophylaxis of women and children. In March 2010, the International AIDS Society and 15 partners launched a Consensus Statement outlining priority areas in which a relative lack of knowledge impedes delivery of optimal prevention of mother to child transmission (PMTCT) and treatment to women and children.

The Consensus Statement, "Asking the Right Questions: Advancing an HIV Research Agenda for Women and Children", makes a special appeal for a more gender-sensitive approach to HIV research at all stages, from conception to design and implementation. It particularly emphasizes research to enhance the understanding of sex-based differences and paediatric needs in treatment uptake and response. In addition to clinical issues, the statement focuses on programmatic research that facilitates access and adherence to antiretroviral regimens. Better coordination of HIV management with sexual and reproductive healthcare delivery is one such approach.

We discuss here our knowledge gaps concerning effective, safe PMTCT and treatment for women and children in light of the expansion envisioned by WHO's revised guidelines. The guideline's new goals present an opportunity for advancing the women and children's agenda outlined in the Consensus Statement.
Oshima Shipbuilding Company
Creators: name: Patrick, Hugh T.
Publisher: name: Columbia University
Year: 2015
Subjects: Business

description: Oshima Shipbuilding is one of many mid‐size Japanese companies that are major global players in niche markets. This essay tells the Oshima story in the context of the global shipbuilding industry’s cycles, changing competitors, and evolving technologies. The industry is subject to wide, rapid swings in demand and pricing, primarily for exogenous reasons. Oshima, a builder of mid‐size bulk carriers, has survived, and even prospered, through productivity growth, technological innovation, and earning a reputation for quality.
Nagasaki Jidousya Co., Ltd.
Creators: name: Patrick, Hugh T.
Publisher: name: Columbia University
Year: 2015
Subjects: Business

description: I visited the head office of the Nagasaki Bus Company in Nagasaki City in May 2014. The company’s main business is providing regular bus services both within Nagasaki City and from the city throughout Nagasaki Prefecture. It also provides a variety of special bus services, such as to hospitals and for major Nagasaki companies. Furthermore, it holds extensive – and quite profitable – real estate holdings which are being developed into urban shopping centers, office buildings, condos, and hotels. The company’s challenge is that its bus service loses money, despite providing an essential public service making 4,000 trips a day, along with regular service to Osaka and to Nagoya, amounting to sales of $95.8 million in 2013. Moreover, the number of passengers has been declining ever since the 1980s when young people began buying cars, and will continue to decline as the Nagasaki City population, now 440,000, may decline to about 300,000 in the next 20 years. The company is attempting to address this challenge by developing special bus services for the elderly to hospitals, shopping, and tourist trips. For now, the company is profitable on the strength of its real estate holdings, but given these budgetary and demographic realities, the future is unclear.
The VLTI/MIDI survey of massive young stellar objects - Sounding the inner regions around intermediate- and high-mass young stars using mid-infrared interferometry
Creators: name: Boley, Paul A.
name: Linz, Hendrik
name: van Boekel, Roy
name: Henning, Thomas
name: Feldt, Markus
name: Kaper, Lex
name: Leinert, Christoph
name: Mueller, Andre
name: Pascucci, Ilaria
name: Roberto, Massimo
name: Stecklum, Bringfried
name: Waters, L. B. F. M.
name: Zinnecker, Hans
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We aim to characterize the distribution and composition of circumstellar material around young massive stars, and to investigate exactly which physical structures in these objects are probed by long-baseline mid-infrared interferometric observations. We used the two-telescope interferometric instrument MIDI of the Very Large Telescope Interferometer of the European Southern Observatory to observe a sample of 24 intermediate- and high-mass young stellar objects in the N band (8-13 micron). We had successful fringe detections for 20 objects, and present spectrally-resolved correlated fluxes and visibility levels for projected baselines of up to 128 m. We fit the visibilities with geometric models to derive the sizes of the emitting regions, as well as the orientation and elongation of the circumstellar material. Fourteen objects in the sample show the 10 micron silicate feature in absorption in the total and correlated flux spectra. For 13 of these objects, we were able to fit the correlated flux spectra with a simple absorption model, allowing us to constrain the composition and absorptive properties of the circumstellar material. Nearly all of the massive young stellar objects observed show significant deviations from spherical symmetry at mid-infrared wavelengths. In general, the mid-infrared emission can trace both disks and outflows, and in many cases it may be difficult to disentangle these components on the basis of interferometric data alone, because of the sparse spatial frequency coverage normally provided by current long-baseline interferometers. For the majority of the objects in this sample, the absorption occurs on spatial scales larger than those probed by MIDI. Finally, the physical extent of the mid-infrared emission around these sources is correlated with the total luminosity, albeit with significant scatter.
description: 36 pages, 22 figures. Accepted to Astronomy and Astrophysics
Sonnenfleckenzeichnung Nr. 158.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.06.1990, 07:30, erstellt von Michele Bianda, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
The VV'P form factors in resonance chiral theory and the pi-eta-eta' light-by-light contribution to the muon g-2
Creators: name: Roig, P.
name: Guevara, A.
name: Castro, G. López
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The description of the VV'P form factors (V,V' stands for vector particles and P for a pseudoscalar meson) for different particles virtualities remains a challenge for the theory of strong interactions. While their chiral limit is well understood, recent measurements of the gamma^* omega pi^0 and gamma^* gamma pi^0 form factors at high photon virtualities seem to depart from the simplest scaling behavior suggested by QCD. Here we attempt to describe them in their whole measured energy regimes within the Resonance Chiral Theory, a framework which naturally incorporates the chiral limit constraints and extends to higher energies by including the resonances as active fields. Specifically, we obtained an accurate description of the data up to 2 GeV on the former form factor by including three multiplets of vector resonances. Good agreement with measurements of the latter was possible even in the single resonance approximation, although we propose to measure the e^+e^- to mu^+mu^-pi^0 cross-section and di-muon invariant mass distribution to better characterize this form factor. We have then evaluated the pion exchange contribution to the muon g-2 obtaining (6.66\pm0.21)x10^{-10} with an accurate determination of the errors. We have also recalled that approximating the whole pion exchange by the pion pole contribution underestimates the corresponding result for the anomaly (by (15,20)%). Based on these results, we have predicted the eta^(\prime) transition form factors obtaining good agreement with data and obtained their respective contributions to the muon anomaly. In this way, the contribution of the three lightest pseudoscalars to it yields (10.47\pm0.54)x10^{-10}, in agreement with previous evaluations but with smaller error.
description: 43 pages, 11 figures and 6 tables. v2: Minor changes to match version to be published in PRD
Sonnenfleckenzeichnung Nr. 310.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.12.1990, 08:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 148.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.06.1990, 07:30, erstellt von Michele Bianda, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 319.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.12.1990, 08:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 308.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.12.1990, 08:45, erstellt von Michele Bianda, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
CO rotational line emission from a dense knot in Cas A Evidence for active post-reverse-shock chemistry
Creators: name: Wallström, Sofia H. J.
name: Biscaro, Chiara
name: Salgado, Francisco
name: Black, John H.
name: Cherchneff, Isabelle
name: Muller, Sébastien
name: Berné, Olivier
name: Rho, Jeonghee
name: Tielens, Alexander G. G. M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We report a Herschel detection of high-J rotational CO lines from a dense knot in the supernova remnant Cas A. Based on a combined analysis of these rotational lines, and previously observed ro-vibrational CO lines, we find the gas to be warm (two components at 400 and 2000 K) and dense (1e6-7 cm-3), with a CO column density of 5e17 cm-2. This, along with the broad line widths (400 kms-1), suggests that the CO emission originates in the post-shock region of the reverse shock. As the passage of the reverse shock dissociates any existing molecules, the CO has most likely reformed in the last few years, in the post-shock gas. The CO cooling time is comparable to the CO formation time, so possible heating sources (UV photons from the shock front, X-rays, electron conduction) to maintain the large column density of warm CO are discussed.
description: Accepted to A&A Letters, 4 pages, 4 figures
Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity
Creators: name: Funahashi, Yasuhiro
name: Shawber, Carrie
name: Sharma, Anshula
name: Kanamaru, Emi
name: Choi, Yun
name: Kitajewski, Jan K.
Publisher: name: Columbia University
Year: 2011
Subjects: Oncology
Obstetrics
Gynecology

description: In the vasculature, Notch signaling functions as a downstream effecter of Vascular Endothelial Growth Factor (VEGF) signaling. VEGF regulates sprouting angiogenesis in part by inducing and activating matrix metalloproteases (MMPs). This study sought to determine if VEGF regulation of MMPs was mediated via Notch signaling and to determine how Notch regulation of MMPs influenced endothelial cell morphogenesis. We assessed the relationship between VEGF and Notch signaling in cultured human umbilical vein endothelial cells. Overexpression of VEGF-induced Notch4 and the Notch ligand, Dll4, activated Notch signaling, and altered endothelial cell morphology in a fashion similar to that induced by Notch activation. Expression of a secreted Notch antagonist (Notch1 decoy) suppressed VEGF-mediated activation of endothelial Notch signaling and endothelial morphogenesis. We demonstrate that Notch mediates VEGF-induced matrix metalloprotease activity via induction of MMP9 and MT1-MMP expression and activation of MMP2. Introduction of a MMP inhibitor blocked Notch-mediated endothelial morphogenesis. In mice, analysis of VEGF-induced dermal angiogenesis demonstrated that the Notch1 decoy reduced perivascular MMP9 expression. Taken together, our data demonstrate that Notch signaling can act downstream of VEGF signaling to regulate endothelial cell morphogenesis via induction and activation of specific MMPs. In a murine model of VEGF-induced dermal angiogenesis, Notch inhibition led to reduced MMP9 expression.
Sonnenfleckenzeichnung Nr. 108.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.05.1990, 07:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Geometric inequalities for black holes
Creators: name: Dain, Sergio
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: It is well known that the three parameters that characterize the Kerr black hole (mass, angular momentum and horizon area) satisfy several important inequalities. Remarkably, some of these inequalities remain valid also for dynamical black holes. This kind of inequalities play an important role in the characterization of the gravitational collapse. They are closed related with the cosmic censorship conjecture. In this article recent results in this subject are reviewed.
description: Invited review article for General Relativity and Gravitation. Based on my plenary lecture at GR20 and the longer review article Classical and Quantum Gravity, 29(7):073001, 2012, arXiv:1111.3615. 27 pages. 14 figures. Minor changes
Sonnenfleckenzeichnung Nr. 123.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.05.1990, 07:15, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: A rare complication of ventriculoperitoneal shunt: Right scrotal abscess due to ventriculoperitoneal shunt catheter migration.
Creators: name: Vicaría, Iván
Publisher: name: EURORAD
Year: 2022
Subjects: subject: Uroradiology & genital male imaging
subject: Abdomen
subject: Genital / Reproductive system male
subject: Conventional radiography
subject: CT
subject: Ultrasound
subject: Clinical Cases

description: Clinical History: 80 years old male with normotensive hydrocephalus treated by ventriculoperitoneal shunt. The patient was submitted to this treatment 47 days ago when he arrived to the emergency department with abdominal pain, mainly in the right flank and the right lower quadrant. Biochemistry revealed leukocytosis, neutrophilia and inflammatory parameters elevation. While doing the ultrasonographic study we found scrotal swelling and we made a selective examination of the scrotum. 

description: 80 years, male
Sonnenfleckenzeichnung Nr. 128.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.05.1990, 07:15, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Packing under convex quadratic constraints
Creators: name: Klimm, Max
name: Pfetsch, Marc E.
name: Raber, Rico
name: Skutella, Martin
Publisher: name: Technische Universität Berlin
Year: 2021
Subjects: subject: 500 Naturwissenschaften und Mathematik::510 Mathematik::510 Mathematik
subject: convex quadratic constraints
subject: constant-factor approximation algorithms
subject: greedy strategy

description: We consider a general class of binary packing problems with a convex quadratic knapsack constraint. We prove that these problems are APX-hard to approximate and present constant-factor approximation algorithms based upon two different algorithmic techniques: a rounding technique tailored to a convex relaxation in conjunction with a non-convex relaxation, and a greedy strategy. We further show that a combination of these techniques can be used to yield a monotone algorithm leading to a strategyproof mechanism for a game-theoretic variant of the problem. Finally, we present a computational study of the empirical approximation of these algorithms for problem instances arising in the context of real-world gas transport networks.
Time-dependent polarization states of high power, ultrashort laser pulses during atmospheric propagation
Creators: name: Palastro, J. P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Optics (physics.optics)
subject: Atomic Physics (physics.atom-ph)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: We investigate, through simulation, the evolution of polarization states during atmospheric propagation of high power, ultrashort laser pulses. A delayed rotational response model handling arbitrary, transverse polarization couples both the amplitude and phase of the polarization states. We find that, while circularly and linearly polarized pulses maintain their polarization, elliptically polarized pulses become depolarized due to energy equilibration between left and right circularly polarized states. The depolarization can be detrimental to remote radiation generation schemes and obscures time-integrated polarization measurements.
Sonnenfleckenzeichnung Nr. 156.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.06.1990, 14:15, erstellt von Michele Bianda, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Adherence and virologic suppression during the first 24 weeks on antiretroviral therapy among women in Johannesburg, South Africa - a prospective cohort study
Creators: name: El-Khatib, Ziad
name: Ekstrom, Anna
name: Coovadia, Ashraf
name: Abrams, Elaine J.
name: Petzold, Max
name: Katzenstein, David
name: Morris, Lynn
name: Kuhn, Louise
Publisher: name: Columbia University
Year: 2011
Subjects: Public health
Epidemiology

description: Adherence is a necessary part of successful antiretroviral treatment (ART). We assessed risk factors for incomplete adherence among a cohort of HIV-infected women initiating ART and examined associations between adherence and virologic response to ART. A secondary data analysis was conducted on a cohort of 154 women initiating non-nucleoside reverse transcriptase inhibitor (NNRTI)-based ART at a single site in Johannesburg, South Africa. Ninety women had been enrolled in a prevention of mother-to-child transmission (pMTCT) program and were exposed to single-dose nevirapine (sdNVP) >18 months earlier. Women were interviewed pre-treatment and clinical, virologic and adherence data were collected during follow-up to 24 weeks. Incomplete adherence to ART was defined as returning >5% of medications, estimated by pill counts at scheduled visits. Multivariable logistic regression analysis and unadjusted odds ratio (95%CI) were performed, using STATA/SE (ver 10.1). About half of the women (53%) were <30 years of age, 63% had <11 years of schooling, 69% were unemployed and 37% lived in a shack. Seven percent of women had a viral load >400 copies/ml at 24 weeks and 37% had incomplete adherence at one or more visits. Incomplete adherence was associated with less education (p = 0.01) and lack of financial support from a partner (p = 0.02) after adjustment for confounders. Only when adherence levels dropped below 80% was there a significant association with viremia in the group overall (p = 0.02) although adherence <95% was associated with viremia in the sdNVP-exposed group (p = 0.03). The main reasons for incomplete adherence were being away from home, busy with other things and forgetting to take their medication. Virologic response to NNRTI-treatment in the cohort was excellent. However, women who received sdNVP were at greater risk of virologic failure when adherence was <95%. Women exposed to sdNVP, and those with less education and less social support may benefit from additional adherence counseling to ensure the long-term success of ART. More than 80% adherence may be sufficient to maintain virologic suppression on NNRTI-based regimens in the short-term, however complete adherence should be encouraged.
Sonnenfleckenzeichnung Nr. 215.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.08.1990, 08:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 313.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.12.1990, 08:45, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 175.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 18.07.1990, 07:45, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Final-state interactions effects in neutral-current neutrino and antineutrino cross sections at MiniBooNE kinematics
Creators: name: Meucci, Andrea
name: Giusti, Carlotta
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The analysis of the recent neutral-current elastic neutrino and antineutrino-nucleus scattering cross sections measured by the MiniBooNE Collaboration requires relativistic theoretical descriptions also accounting for the role of final-state interactions. In this work we investigate the sensitivity to final-state interactions and compare the MiniBooNE data with the results obtained in the relativistic Green's function model with different parameterizations for the phenomenological relativistic optical potential.
description: 4 pages, 3 figures. version published in Physical Review D
Sonnenfleckenzeichnung Nr. 107.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.05.1990, 07:45, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 207.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.08.1990, 08:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 219.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 31.08.1990, 14:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)