cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Relevance of the regional lymph node in scrapie pathogenesis after peripheral infection of hamsters
Creators: name: Kratzel, Christine
name: Krüger, Dominique
name: Beekes, Michael
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2007
Subjects: subject: Animals
subject: Female
subject: Male
subject: Blotting
subject: Western
subject: Cricetinae
subject: Disease Models
subject: Animal
subject: Lymph Node Excision
subject: Lymph Nodes/metabolism
subject: Lymph Nodes/physiopathology
subject: Mesocricetus
subject: PrPSc Proteins/metabolism
subject: PrPSc Proteins/pathogenicity
subject: Scrapie/physiopathology
subject: 610 Medizin

description: Background: The exact role of the lymphoreticular system in the spread of peripheral prion infections to the central nervous system still needs further elucidation. Against this background, the influence of the regional lymph node (Ln. popliteus) on the pathogenesis of scrapie was monitored in a hamster model of prion infection via the footpad. Methods: Surgical lymphadenectomy was carried out at different time points after infection, or prior to inoculation, in order to elucidate the impact of the lymph node on lethal neuroinvasion. Results: The Ln. popliteus did not show an influence on pathogenesis when a high dose of infectivity was administered. However, it was found to modulate the interval of time until the development of terminal scrapie in a subset of animals lymphadenectomized after low-dose infection. In additon, lymphadenectomy performed four weeks before inoculation prevented cerebral PrPTSE deposition and development of disease during the period of observation (314 days) in the majority of hamsters challenged with a very low dose of scrapie agent. Conclusion: Our findings suggest the regional lymph node as a potentially facilitating or even essential factor for invasion of the brain after peripheral challenge with low doses of infectious scrapie agent. The invasive in vivo approach pursued in this study may be applied also to other animal species for further elucidating the involvement of lymphoid tissue in the pathogenesis of experimental and natural TSEs.
Literature and Medicine: Twenty-Five Years Later
Creators: name: Logan, Peter M.
Publisher: name: Humanities Commons
Year: 2008
Subjects: subject: Literature and medicine
subject: Criticism
subject: Interdisciplinary approach to knowledge
subject: Culture--Study and teaching
subject: Interdisciplinary approach in education
subject: Art and science
subject: Science
subject: Nineteenth century
subject: Medicine
subject: History

description: An analysis of ten studies in Victorian literature and medicine examines the changes in the interdisciplinary field since G. S. Rousseau published an influential article on the topic in 1981.
title: The Profound Teachings of Lord Krishna: An Exploration of Spiritual Wisdom
title: A Journey into the Divine
titleType: Subtitle
Creators: name: Kallol, Chakrabarti
Publisher: name: Zenodo
Year: 2024

description:     Lord Krishna, revered as a symbol of divine love, wisdom, and compassion, frequently encounters misinterpretations of his true essence. Notably, prevailing misconceptions, such as the portrayal of his numerous romantic liaisons, obscure the substantial spiritual insights he offers. In essence, Krishna's life and divine pastimes, known as ‘leelas,’ represent a unique manifestation of transcendental love, illustrating the eternal relationship between the soul and the divine. His teachings, prominently featured in the Bhagavad Gita, provide essential guidance for ethical living and the attainment of spiritual fulfillment. This discourse aims to elucidate ten fundamental teachings of Krishna and their significance for contemporary humanity.
Questions and answers on "JavaScript Affogato: Programming a Culture of Improvised Expertise"
Creators: name: Lennon, Brian
name: Shea, Brian
Publisher: name: Johns Hopkins University Press
Year: 2018
Subjects: subject: Web site development
subject: Culture--Data processing
subject: Culture--Study and teaching

description: Published by Johns Hopkins University Press Blog, 28 March 2018. A Q&A about the essay "JavaScript Affogato: Programming a Culture of Improvised Expertise," published in Configurations 26.1 (2018): 47–72, DOI: 10.1353/con.2018.0002.
Virtual Hyperspectral Imaging Toward Data-Driven mHealth
Creators: name: Visbal Onufrak, Michelle A.
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Biomedical engineering not elsewhere classified
Mobile computing

description: Hyperspectral imaging is widely used for obtaining optical information of light absorbers (e.g. biochemical composition) in a variety of specimens or tissues in a label-free manner. Acquiring and processing spectral data using hyperspectral imaging usually requires advanced instrumentation such as spectrometers, spectrographs or tunable color filters, which are not easily adaptable in developing instrumentation for field-based applications. Also, use of only RGB information from conventional cameras is not sufficient to obtain a reliable correlation with the actual content of the analyte of interest. We propose a new concept of ‘virtual hyperspectral imaging’ to reconstruct the full reflectance spectra from RGB image data. This allows us to use only RGB image data to determine detailed spatial distributions of analytes of interest. More importantly, it simplifies instrumentation without requiring bulky and expensive hardware. Using a data-driven approach, we apply multivariate regression to reconstruct hyperspectral reflectance image data from RGB images obtained using a conventional camera or a smartphone. In developing a reliable reconstruction matrix, it is critical to obtain a training data set of the specimen of study under the same optical geometry since the spectral reflectance and absorbance is sensitive to the detection and illumination parameters. We designed an image-guided hyperspectral system that can acquire both hyperspectral reflectance and RGB data sets under the same imaging configuration to minimize any discrepancies in the hyperspectral reflectance data acquired using different optical sensing geometries. In our technology development, a telecentric lens that is commonly used in machine vision systems but rarely in bioimaging, serves as a key component for reducing unwanted scattering in biological tissue due to its highly anisotropic scattering properties, by acting as a back-directional gating component to suppress diffuse light. We evaluate our spectrometer-less reflectance imaging method using RGB-based hyperspectral reconstruction algorithm for integration into a smartphone application for non-invasive hemoglobin analysis for anemia risk assessment in communities with limited access to central laboratory tests.
Malaria transmission in non-endemic areas: case report, review of the literature and implications for public health management
Creators: name: Zoller, Thomas
name: Naucke, Torsten J
name: May, Jürgen
name: Hoffmeister, Bodo
name: Flick, Holger
name: Williams, Christopher J.
name: Frank, Christina
name: Bergmann, Frank
name: Suttorp, Norbert
name: Mockenhaupt, Frank P.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2009
Subjects: subject: Animals
subject: DNA
subject: Humans
subject: Anopheles
subject: Protozoan/analysis
subject: Female
subject: Genotype
subject: Germany
subject: Insect Vectors/parasitology
subject: Malaria Falciparum/diagnosis
subject: Malaria Falciparum/parasitology
subject: Malaria Falciparum/transmission
subject: Plasmodium falciparum/genetics
subject: Plasmodium falciparum/isolation & purification
subject: Polymerase Chain Reaction
subject: Pregnancy
subject: Public Health
subject: Travel
subject: 610 Medizin

description: In non-endemic areas, malaria is rare and locally acquired infections, particularly with Plasmodium falciparum, are exceptional events. The diagnosis is, therefore, likely to be delayed or missed in patients without a relevant travel history. This report describes a case of falciparum malaria in Berlin, Germany, in a patient who had not been to an endemic area for more than a decade. Potential routes of vector-related and direct transmission were evaluated, particularly with regard to a possible danger to the public. A review of the literature was conducted regarding possible routes of transmission and their probability assessed. Genotyping of parasite isolates of this and another patient with malaria admitted 16 days before revealed homology between the two strains. In a local entomological survey, anopheline vectors on the hospital grounds as well as in the residential area of both patients were found. Despite intensive investigations, the mode of transmission remained obscure. In this context, possible routes of vector-borne and direct occupational/accidental transmission in a major European city are reviewed and discussed, providing information and guidance in case other similar events occur elsewhere. Examples for investigations and measures to be taken in such a situation are provided. When local malaria transmission within a large non-immune population cannot be ruled out, genotyping of parasite isolates, local entomological surveys, preparedness for secondary cases, expert consultations in a multidisciplinary team and careful information management are essential. Malaria acquired in nonendemic areas remains an unlikely, but possible event for which awareness needs to be maintained.
Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach
Creators: name: Paraskevis, Dimitrios
name: Pybus, Oliver
name: Magiorkinis, Gkikas
name: Hatzakis, Angelos
name: Wensing, Annemarie M. J.
name: Vijver, David A. M. C. Van De
name: Albert, Jan
name: Angarano, Guiseppe
name: Hamouda, Osamah
name: Balotta, Claudia
name: Boeri, Enzo
name: Camacho, Ricardo
Publisher: name: Robert Koch-Institut; Robert Koch-Institut, Infektionsepidemiologie
Year: 2009
Subjects: subject: DNA
subject: Humans
subject: Molecular
subject: Sequence Analysis
subject: Phylogeny
subject: Cluster Analysis
subject: Contact Tracing/methods
subject: Epidemiology
subject: Europe/epidemiology
subject: HIV Infections/epidemiology
subject: HIV Infections/transmission
subject: HIV Infections/virology HIV-1/classification HIV-1/genetics HIV-1/isolation &
subject: purification
subject: Israel/epidemiology
subject: 610 Medizin

description: Background: The prevalence and the origin of HIV-1 subtype B, the most prevalent circulating clade among the long-term residents in Europe, have been studied extensively. However the spatial diffusion of the epidemic from the perspective of the virus has not previously been traced. Results: In the current study we inferred the migration history of HIV-1 subtype B by way of a phylogeography of viral sequences sampled from 16 European countries and Israel. Migration events were inferred from viral phylogenies by character reconstruction using parsimony. With regard to the spatial dispersal of the HIV subtype B sequences across viral phylogenies, in most of the countries in Europe the epidemic was introduced by multiple sources and subsequently spread within local networks. Poland provides an exception where most of the infections were the result of a single point introduction. According to the significant migratory pathways, we show that there are considerable differences across Europe. Specifically, Greece, Portugal, Serbia and Spain, provide sources shedding HIV-1; Austria, Belgium and Luxembourg, on the other hand, are migratory targets, while for Denmark, Germany, Italy, Israel, Norway, the Netherlands, Sweden, Switzerland and the UK we inferred significant bidirectional migration. For Poland no significant migratory pathways were inferred. Conclusion: Subtype B phylogeographies provide a new insight about the geographical distribution of viral lineages, as well as the significant pathways of virus dispersal across Europe, suggesting that intervention strategies should also address tourists, travellers and migrants.
Questions and answers on “JavaScript Affogato: Programming a Culture of Improvised Expertise”
Creators: name: Lennon, Brian
name: Shea, Brian
Publisher: name: Humanities Commons
Year: 2018
Subjects: subject: Web site development
subject: Culture--Study and teaching
subject: Culture--Data processing

description: Published by Johns Hopkins University Press Blog, 28 March 2018. A Q&A about the essay “JavaScript Affogato: Programming a Culture of Improvised Expertise,” published in Configurations 26.1 (2018): 47–72, DOI: 10.1353/con.2018.0002.
On the Structured Eigenvalue Problem: Methods, Analysis, and Applications
Creators: name: Vogel, James P.
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Numerical analysis

description: This PhD thesis is an important development in the theories, methods, and applications of eigenvalue algorithms for structured matrices. Though eigenvalue problems have been well-studied, the class of matrices that admit very fast (near-linear time) algorithms was quite small until very recently. We developed and implemented a generalization of the famous symmetric tridiagonal divide-and-conquer algorithm to a much larger class of rank structured matrices (symmetric hierarchically semisperable, or HSS) that appear frequently in applications. Altogether, this thesis makes valuable contributions to three different major areas of scientific computing: algorithmic development, numerical analysis, and applications. In addition to the previously stated divide-and-conquer algorithm, we generalize to larger classes of eigenvalue problems and provide several key new low-rank update algorithms. A major contribution the analysis of the structured eigenvalue problem. In addition to standard perturbation analysis, we elucidate some subtle and previously under-examined issues in structured matrix eigenvalue problems such as subspace contributions and secular equation conditioning. Finally, several applications are studied.
3. ASPECTOS RELEVANTES DA DISPENSA DE PEQUENO VALOR
Creators: name: Ministério Público de Contas do Estado de Minas Gerais
Publisher: name: Zenodo
Year: 2024

description: A Lei n. 14.133/2021, Nova Lei de Licitações e Contratos Administrativos, trouxe algumas novidadescomparada à legislação anterior com relação à dispensa de licitação envolvendo aquisições de pequeno valor,algumas delas inspiradas no entendimento consolidado da doutrina e jurisprudência, sobretudo do Tribunalde Contas da União (TCU), ou mesmo na prática administrativa. Neste artigo, serão analisadas a ampliação doselementos imprescindíveis do processo de contratação direta, bem como dos valores de referências; as regrassobre o somatório das dispensas para evitar o fracionamento indevido; o procedimento eletrônico, que temsido denominado de “dispensa eletrônica”, e a utilização de cartão de pagamento para fazer face às despesasde pequeno valor, com intuito de perquirir se as alterações e introduções levadas a efeito pela nova lei delicitações têm o condão de aprimorar o processo de contratação direta de pequeno valor e melhorá-lo em termosde segurança jurídica, eficiência, competitividade e transparência. A relevância da pergunta reside no fato daexpressividade numérica das contratações diretas de pequeno valor, responsável, no âmbito federal, por 61% doquantitativo total das compras públicas, segundo relatório de avaliação da Controladoria-Geral da União (CGU)referente ao exercício de 2019 sobre a gestão das contratações públicas. O presente trabalho foi desenvolvidosob a vertente jurídico-dogmática, com análise teórica do instituto da dispensa de licitação de pequeno valorprevisto no art. 75 da Lei n. 14.133/2021. Procedeu-se ao levantamento de dados primários (leis e atos normativosenvolvendo contratações públicas e decisões das Cortes de Contas), bem como de dados secundários (estudos ebibliografia sobre o assunto). Como conclusão, apurou-se que as alterações promovidas pela nova lei de licitaçõespossuem potencial para aprimorar o processo, embora algumas novidades dependam de implementação desistemas eletrônicos e regulamentações internas
Additional file 1 of Loss of p16 does not protect against premature ovarian insufficiency caused by alkylating agents
Creators: name: Liu, Fei
name: Wan, Qin
name: Liu, Pengfei
name: Miao, Dengshun
name: Dai, Xiuliang
name: Chen, Li
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Supplementary material 1
Vernacular Soliloquy, Theatrical Gesture, and Embodied Consciousness in The Marrow of Tradition
Creators: name: Rinehart, Nicholas
Publisher: name: Humanities Commons
Year: 2018
Subjects: subject: American literature--African American authors
subject: Performance art--Study and teaching
subject: Fiction
subject: Narration (Rhetoric)
subject: African Americans--Social life and customs
subject: African Americans

description: Charles Chesnutt’s Marrow of Tradition (1901) is overwhelmingly understood as an historical novel. Critics have again and again focused on its journalistic historicity; its ambivalent racial politics; its attitudes towards assimilation, separatism, vengeance, and resistance; and Chesnutt’s alleged biographical identification with various characters. This generalized preoccupation with the explicitly political or historical contours of the novel frequently precludes closer scrutiny of Chesnutt’s formal literary strategies. This paper shirks that tendency by considering The Marrow of Tradition not just as an historical novel, but also as a novel of consciousness. Viewing the novel from the perspective of its representation of consciousness both reframes its historiographical bearing and opens up new ways to understand Chesnutt’s fiction and nineteenth-century African American literature. It argues that the location of black consciousness in the novel is the soliloquy, and demonstrates that the soliloquy should be understood as a form of “embodied consciousness”: a narrative mode endowed with the expressivity of theatrical gesture. It further examines these performative gestures in relation to additional patterns in the novel: first, the destructive circulation of written, material texts; and second, recurring images of corporeality and physical breakdown wherein one’s capacity for speech is endangered. As they are invulnerable to such formal compromise and breakdown, Chesnutt’s soliloquies together produce a counter-archive of vernacular memory and reveal how dramatic form functions in the novel more broadly.
sj-docx-1-tej-10.1177_20417314211027714 – Supplemental material for Development of a Bioartificial Vascular Pancreas
Creators: name: Han, Edward X
name: Wang, Juan
name: Kural, Mehmet
name: Jiang, Bo
name: Leiby, Katherine L
name: Chowdhury, Nazar
name: Tellides, George
name: Kibbey, Richard G
name: Lawson, Jeffrey H
name: Niklason, Laura E
Publisher: name: SAGE Journals
Year: 2021
Subjects: Dentistry not elsewhere classified
Biological Sciences not elsewhere classified

description: Supplemental material, sj-docx-1-tej-10.1177_20417314211027714 for Development of a Bioartificial Vascular Pancreas by Edward X Han, Juan Wang, Mehmet Kural, Bo Jiang, Katherine L Leiby, Nazar Chowdhury, George Tellides, Richard G Kibbey, Jeffrey H Lawson and Laura E Niklason in Journal of Tissue Engineering
Applied epidemiology training in Europe: quite a success - but more to be done
Creators: name: Krause, Gérard
name: Stefanoff, P.
name: Moren, A.
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2009
Subjects: subject: Humans
subject: Population Surveillance
subject: Communicable Disease Control/trends
subject: Epidemiology/education
subject: European Union/organization & administration
subject: Government Programs/trends
subject: Microbiology/education
subject: 610 Medizin

description: This article describes the development of training in applied epidemiology in Europe and outlines the current situation in Europe with a view of how the system can be improved to meet future challenges.
KLARpsy-Text: Fatigue bei Krebs: Wie gut helfen Yoga, psychologische Behandlungen und Achtsamkeitstrainings?
Creators: name: ZPID
Publisher: name: KLARpsy
Year: 2024
Subjects: subject: 150

description: KLARpsy-Texte sind kurze, lai:innengerechte, allgemeinverständliche und richtlinienbasierte Zusammenfassungen psychologischer Übersichtsarbeiten. Dieser KLARpsy-Text hat den Titel 'Fatigue bei Krebs: Wie gut helfen Yoga, psychologische Behandlungen und Achtsamkeitstrainings?'. Er wurde von Mitarbeitenden des Leibniz-Instituts für Psychologie verfasst. Als testlesende Person war Werner Heene beteiligt. Der KLARpsy-Text befasst sich mit folgenden Inhalten: Fatigue tritt häufig im Zusammenhang mit Krebs und Krebsbehandlungen auf. Die quälende Erschöpfung und extreme Müdigkeit sind sehr belastend für die Betroffenen. Derzeit gibt es jedoch keine wirksamen Medikamente gegen Fatigue. Studien liefern Hinweise darauf, dass andere Behandlungen helfen könnten. Dazu zählen neben Yoga und Achtsamkeitstrainings auch psychologische Behandlungen. Sie gehen zum Beispiel auf problematische Überzeugungen ein oder helfen Menschen, sich besser zu entspannen. Mit ihrer Übersichtsarbeit wollten die Forschenden herausfinden: 1. Helfen Yoga, psychologische Behandlungen und Achtsamkeitstrainings bei krebsbedingter Fatigue? 2. Welchen Merkmale der Behandlungen, zum Beispiel in der Gruppe oder alleine, helfen am besten? Yoga, psychologische Behandlungen und Achtsamkeitstrainings helfen Menschen, die an krebsbedingter Fatigue leiden. Psychologische Behandlungen helfen besonders gut, wenn sie in der Gruppe durchgeführt werden und problematische Gedanken und Überzeugungen bearbeiten.
Methicillin-resistant Staphylococcus aureus ST398 in humans and animals, Central Europe.
Creators: name: Witte, Wolfgang
name: Strommenger, Birgit
name: Stanek, Christian
name: Cuny, Christiane
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2007
Subjects: subject: Humans
subject: Animals
subject: Europe/epidemiology
subject: Swine
subject: Swine Diseases/epidemiology
subject: Methicillin Resistance
subject: Staphylococcus aureus/drug effects
subject: Staphylococcal Infections/microbiology
subject: Staphylococcal Infections/veterinary
subject: Swine Diseases/microbiology
subject: Dogs
subject: Dog Diseases/epidemiology
subject: Dog Diseases/microbiology
subject: Horse Diseases/epidemiology
subject: Horse Diseases/microbiology
subject: Horses
subject: Staphylococcus aureus/classification
subject: 610 Medizin

description: Methicillin-resistant Staphylococcus aureus of clonal lineage ST398 that exhibits related spa types and contains SCCmec elements of types IVa or V has been isolated from colonized and infected humans and companion animals (e.g., dog, pig, horse) in Germany and Austria. Of particular concern is the association of these cases with cases of nosocomial ventilator-associated pneumonia.
Ces traîtres qui affament notre peuple. Argent et antisémitisme dans la « Recherche »  proustienne
Creators: name: Verna, Marisa
Publisher: name: Humanities Commons
Year: 2017
Subjects: subject: French--Social life and customs
subject: Twenty-first century
subject: French literature

description: The Jewish 'question' is treated in the Recherche by way of the Dreyfus Affaire, which is not spoken of but scattered in the discourses of different characters. Definitions, opinions, even facts are, therefore, spread in the ubiquity of social instability, so that it is impossible for the reader to identify any of Proust's ideologies.In our paper we are going to check on the topic of the "rich Jew", often accused by other characters to starve the French folk: Bloch's excessive greed of success and money is for example described from both points of view of Jewish society and aristocratic Salons. On the other hand, we are going to analyze the passages in which money is the pivot of narrative action that provokes most of social shifts around the “Dreyfus Affaire”.Anti-Semitism in the Recherche is relied to economic and social patterns, and Proust confuses the issue meshing all opinions on the matter. Dreyfus' partisans are often greed, while his accusers are often more honest than their adversaries. In any case, anti-Semitism is no more grounded on the medieval culture of Charlus (Jews are the murderers of God). Contemporary anti-Semitism is described by Proust as a political, economic and social phenomenon
Reinventing Race, Colonization, and Globalisms across Deep Time: Lessons from the Longue Durée
Creators: name: Heng, Geraldine
Publisher: name: Humanities Commons
Year: 2015
Subjects: subject: Comparative literature
subject: Critical race theory
subject: Race
subject: Ethnicity
subject: World history
subject: Religion
subject: Imperialism
subject: History

description: Critically surveys the long premodern history of race and racism, colonization and imperialism, and globalism, across c. 1000-1500 CE.
KLARpsy-Text: Was passiert im Gehirn, wenn wir das Arbeitsgedächtnis trainieren?
Creators: name: ZPID
Publisher: name: KLARpsy
Year: 2025
Subjects: subject: 150

description: KLARpsy-Texte sind kurze, lai:innengerechte, allgemeinverständliche und richtlinienbasierte Zusammenfassungen psychologischer Übersichtsarbeiten. Dieser KLARpsy-Text hat den Titel “Was passiert im Gehirn, wenn wir das Arbeitsgedächtnis trainieren?”. Er wurde von Mitarbeitenden des Leibniz-Instituts für Psychologie verfasst. Eine anonyme testlesende Person war beteiligt. Der KLARpsy-Text befasst sich mit folgenden Inhalten: Das Arbeitsgedächtnis hilft uns, Informationen kurzfristig zu speichern und zu verarbeiten – zum Beispiel beim Rechnen oder Planen. Lange Zeit dachte man, das Arbeitsgedächtnis sei von Natur aus begrenzt und durch Training nicht zu verbessern. Neuerdings versprechen Trainingsprogramme das Gegenteil. Diese Übersichtsarbeit untersucht, ob und wie sich die Aktivität im Gehirn bei einem solchen Training verändert. Mit ihrer Übersichtsarbeit wollten die Forschenden herausfinden: 1. Welche Bereiche im Gehirn werden beim Training des Arbeitsgedächtnisses aktiv? 2. Gibt es Bereiche, die nach dem Training aktiver oder weniger aktiv sind? Während des Trainings des Arbeitsgedächtnisses sind bestimmte Bereiche des Stirn- und Scheitellappens aktiv. Zudem zeigen die Bereiche nach dem Training weniger Aktivität als vor dem Training. Das könnte darauf hindeuten, dass sie wirksamer arbeiten.
Samuel Williams and His World
Creators: name: Ashton, Susanna Margaret
Publisher: name: unknown
Year: 2018
Subjects: subject: Slave narratives
subject: Slavery
subject: Authorship
subject: African Americans--Social life and customs
subject: Autobiography
subject: History
subject: Culture--Study and teaching

description: This is a digital exhibit about the life and work of Samuel Williams, a man who survived slavery in Charleston South Carolina and lived to write his memoir Before the War and After the Union, under "Sam Aleckson." This exhibit and article is the first time his true name has been revealed .
KLARpsy-Text: Blicken Menschen mit sozialer Angststörung anders auf Gesichtsausdrücke ihrer Mitmenschen als psychisch Gesunde?
Creators: name: ZPID
Publisher: name: KLARpsy
Year: 2025
Subjects: subject: 150

description: KLARpsy-Texte sind kurze, lai:innengerechte, allgemeinverständliche und richtlinienbasierte Zusammenfassungen psychologischer Übersichtsarbeiten. Dieser KLARpsy-Text hat den Titel 'Blicken Menschen mit sozialer Angststörung anders auf Gesichtsausdrücke ihrer Mitmenschen als psychisch Gesunde?'. Er wurde von Mitarbeitenden des Leibniz-Instituts für Psychologie verfasst. Eine anonyme testlesende Person war beteiligt. Der KLARpsy-Text befasst sich mit folgenden Inhalten: Forschungsergebnisse zeigen, dass sozial ängstliche Menschen Blickkontakt zu anderen generell eher meiden. Dabei ist es egal, welches Gefühl das Gegenüber ausdrückt. Weitere Studien zeigen hingegen, dass sozial ängstliche Menschen bedrohliche Reize und Gesichtsausdrücke eher beachten. Mit ihrer Übersichtsarbeit wollten die Forschenden herausfinden: 1. Blicken Menschen mit sozialer Angststörung im Vergleich zu psychisch Gesunden anderen weniger in die Augen? 2. Richten Betroffene ihren Blick bereits früh eher auf negative, sozial bedrohliche Gesichtsausdrücke? Menschen mit sozialer Angststörung nehmen seltener und kürzer Blickkontakt zu negativen und positiven Gesichtsausdrücken anderer auf als psychisch Gesunde. Sie blicken dagegen länger und häufiger auf verärgerte als auf neutrale Gesichtsausdrücke, wenn beide zusammen erscheinen.
Corynebacterium diphtheriae invasion-associated protein (DIP1281) is involved in cell surface organization, adhesion and internalization in epithelial cells
Creators: name: Ott, Lisa
name: Höller, Martina
name: Gerlach, Roman
name: Hensel, Michael
name: Rheinlaender, Johannes
name: Schäffer, Tilman E
name: Burkovski, Andreas
Publisher: name: Robert Koch-Institut
Year: 2010
Subjects: subject: Cell Line
subject: Humans
subject: Electrophoresis
subject: Microscopy
subject: Bacterial Adhesion
subject: Bacterial Outer Membrane Proteins/genetics
subject: Bacterial Outer Membrane Proteins/metabolism
subject: Corynebacterium diphtheriae/genetics
subject: Corynebacterium diphtheriae/metabolism
subject: Corynebacterium diphtheriae/physiology
subject: Polyacrylamide Gel
subject: Epithelial Cells/microbiology
subject: Atomic Force
subject: Peptidoglycan/metabolism
subject: 610 Medizin

description: Background: Corynebacterium diphtheriae, the causative agent of diphtheria, is well-investigated in respect to toxin production, while little is known about C. diphtheriae factors crucial for colonization of the host. In this study, we investigated the function of surface-associated protein DIP1281, previously annotated as hypothetical invasion-associated protein. Results: Microscopic inspection of DIP1281 mutant strains revealed an increased size of the single cells in combination with an altered less club-like shape and formation of chains of cells rather than the typical V-like division forms or palisades of growing C. diphtheriae cells. Cell viability was not impaired. Immuno-fluorescence microscopy, SDS-PAGE and 2-D PAGE of surface proteins revealed clear differences of wild-type and mutant protein patterns, which were verified by atomic force microscopy. DIP1281 mutant cells were not only altered in shape and surface structure but completely lack the ability to adhere to host cells and consequently invade these. Conclusions: Our data indicate that DIP1281 is predominantly involved in the organization of the outer surface protein layer rather than in the separation of the peptidoglycan cell wall of dividing bacteria. The adhesion- and invasion-negative phenotype of corresponding mutant strains is an effect of rearrangements of the outer surface.
title: Controlled-environment agriculture for an urbanised world? A comparative analysis of the innovation systems in London, Nairobi and Singapore
Creators: name: Dietze, Victoria
name: Alhashemi, Amna
name: Feindt, Peter H.
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: Urban food production systems
subject: Resource-efficient food production
subject: Innovation system
subject: Institutional framework
subject: Systemic problems
subject: Case study analysis
subject: 630 Landwirtschaft und verwandte Bereiche
subject: 640 Hauswirtschaft und Familie
subject: 650 Management und unterstützende Tätigkeiten
subject: 660 Chemische Verfahrenstechnik und verwandte Technologien

description: Multiple crises and challenges in the food sector are driving a rising need for innovative food production methods that could provide a growing urban population with high-quality, sustainable and healthy food while strengthening the resilience of food systems. Controlled-environment agriculture (CEA) in urban areas has been proposed as one possible pathway to address these demands. Despite its various potential benefits, CEA is still in a conceptual or experimental stage and there has been less research that focuses on the specificities of urban areas where it could be implemented. Using the Urban Food Production Innovation System (UFoPrInS) concept, this paper analyses the urban contexts and enabling and impeding factors for implementing CEA in three contrasting locations: London, Nairobi and Singapore. Based on document analysis and semi-structured expert interviews, our findings show that Singapore is a favourable location because public policies support the implementation of CEA to reduce food import dependency and enhance the resilience of food supply. In London, high food import dependency is increasingly seen as problematic, but the implementation of CEA has been hampered by other policy priorities. In Nairobi, where over half of the population lives in informal settlements without adequate food, water and sanitation, CEA is unlikely to make an economically efficient contribution to food security. We conclude that the implementation of CEA might be suitable in locations with ample capital and knowledge, stable political, social, and infrastructure conditions, and limited space, where value can be linked to hospitality and tourism, supported by positive pricing for resource savings.
sj-pdf-1-ejo-10.1177_11206721211023320 – Supplemental material for Topical corticosteroids with topical cyclosporine A versus topical corticosteroids alone for immunological corneal graft rejection
Creators: name: Marques, Raquel Esteves
name: Leal, Inês
name: Guerra, Paulo Silva
name: Barão, Rafael Correia
name: Quintas, Ana Miguel
name: Rodrigues, Walter
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental material, sj-pdf-1-ejo-10.1177_11206721211023320 for Topical corticosteroids with topical cyclosporine A versus topical corticosteroids alone for immunological corneal graft rejection by Raquel Esteves Marques, Inês Leal, Paulo Silva Guerra, Rafael Correia Barão, Ana Miguel Quintas and Walter Rodrigues in European Journal of Ophthalmology
The Yersinia enterocolitica type three secretion chaperone SycO is integrated into the Yop regulatory network and binds to the Yop secretion protein YscM1
Creators: name: Dittmann, Svea
name: Schmid, Annika
name: Richter, Susanna
name: Trülzsch, Konrad
name: Heesemann, Jürgen
name: Wilharm, Gottfried
Publisher: name: Robert Koch-Institut
Year: 2007
Subjects: subject: Bacterial
subject: Gene Expression Regulation
subject: Protein Binding
subject: Transcription Factors/metabolism
subject: Bacterial Proteins/metabolism
subject: Dimerization
subject: Molecular Chaperones/metabolism
subject: Protein Transport/genetics
subject: Protein Transport/physiology
subject: Yersinia enterocolitica/genetics
subject: Yersinia enterocolitica/metabolism
subject: Yersinia enterocolitica/physiology
subject: 610 Medizin

description: Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virulence plasmid encoding a type three secretion system (T3SS). This T3SS comprises more than 40 constituents. Among these are the transport substrates called Yops (Yersinia outer proteins), the specific Yop chaperones (Sycs), and the Ysc (Yop secretion) proteins which form the transport machinery. The effectors YopO and YopP are encoded on an operon together with SycO, the chaperone of YopO. The characterization of SycO is the focus of this study. Results: We have established the large-scale production of recombinant SycO in its outright form. We confirm that Y. enterocolitica SycO forms homodimers which is typical for Syc chaperones. SycO overproduction in Y. enterocolitica decreases secretion of Yops into the culture supernatant suggesting a regulatory role of SycO in type III secretion. We demonstrate that in vitro SycO interacts with YscM1, a negative regulator of Yop expression in Y. enterocolitica. However, the SycO overproduction phenotype was not mediated by YscM1, YscM2, YopO or YopP as revealed by analysis of isogenic deletion mutants. Conclusion: We present evidence that SycO is integrated into the regulatory network of the Yersinia T3SS. Our picture of the Yersinia T3SS interactome is supplemented by identification of the SycO/YscM1 interaction. Further, our results suggest that at least one additional interaction partner of SycO has to be identified.
Samuel Williams and His World
Creators: name: Ashton, Susanna Margaret
Publisher: name: Humanities Commons
Year: 2018
Subjects: subject: Slavery
subject: History
subject: Slave narratives
subject: African Americans--Social life and customs
subject: Culture--Study and teaching
subject: Autobiography
subject: Authorship

description: This is a digital exhibit about the life and work of Samuel Williams, a man who survived slavery in Charleston South Carolina and lived to write his memoir Before the War and After the Union, under "Sam Aleckson." This exhibit and article is the first time his true name has been revealed .
History, Literature, and Authority in International Law
Creators: name: Warren, Christopher
Publisher: name: unknown
Year: 2018
Subjects: subject: Methodology
subject: Culture and law

description: One consequence of international law's recent historical turn has been to sharpen methodological contrasts between intellectual history and international law. Scholars including Antony Anghie, Anne Orford, Rose Parfitt, and Martti Koskenniemi have taken on board historians' interest in contingency and context but pointedly relaxed historians' traditional stricture against presentist instrumentalism. This essay argues that such a move disrupts a longstanding division of labor between history and international law and ultimately brings international legal method closer to literature and literary scholarship. The essay therefore details several more or less endemic ways in which literature and literary studies confront challenges of presentism, anachronism, meaning, and time. Using examples from writers as diverse as Anghie, Spinoza, Geoffrey Hill, Emily St. John Mandel, China Miéville, John Hollander, Pascale Casanova, Matthew Nicholson, John Selden, Shakespeare, and Dante, it proposes a "trilateral" discussion among historians, international lawyers, and literary scholars that takes seriously the multipolar disciplinary field in which each of these disciplines makes and sustains relations with each of the others.
sj-pdf-1-tau-10.1177_17562872211029784 – Supplemental material for Antiangiogenic tyrosine kinase inhibitors and immunotherapy as first-line treatment for metastatic renal cell carcinoma: is there an increased risk of hypothyroidism?
Creators: name: Roviello, Giandomenico
name: Buti, Sebastiano
name: Cattrini, Carlo
name: Mennitto, Alessia
name: Messina, Carlo
name: Airoldi, Chiara
name: Vannini, Gianmarco
name: Bersanelli, Melissa
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111403 Paediatrics
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-pdf-1-tau-10.1177_17562872211029784 for Antiangiogenic tyrosine kinase inhibitors and immunotherapy as first-line treatment for metastatic renal cell carcinoma: is there an increased risk of hypothyroidism? by Giandomenico Roviello, Sebastiano Buti, Carlo Cattrini, Alessia Mennitto, Carlo Messina, Chiara Airoldi, Gianmarco Vannini and Melissa Bersanelli in Therapeutic Advances in Urology
Developing A Biomimetic In Vitro Model for Vocal Fold Tissue Engineering
Creators: name: Walimbe, Tanaya P.
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Biomedical engineering not elsewhere classified

description: Vocal fold scarring is the fibrotic manifestation of most common pathological voice disorders. Voice disorders lead to direct healthcare costs of over $200 million annually and significantly reduce quality of life for patients. Despite advances in understanding the pathophysiology of vocal fold scarring, effective treatments for scarring and fibrosis remain elusive. The wound-healing cascade associated with vocal fold injury involves complex signaling interactions between cells and their extracellular matrix (ECM), which remain largely unexplored due to the lack of a physiologically relevant preclinical model to study them. Traditional preclinical models do not capture the complex 3D microenvironment of the vocal folds, and the use of stem cells or fibroblasts alone in models has resulted in poor reproducibility and predictability of in vitro models. Toward this end, this work describes the development of a preclinical model that strives to take into account cellular interactions between fibroblasts and epithelial cells and achieve a balance in the native vocal fold 3D environment to function as an in vitro model.
Since a major shortcoming of current in vitro models is the lack of a standardized epithelial fibroblast coculture, initial work focused on developing a coculture system between commercially available tracheal epithelial cells and vocal fold fibroblasts in an in vitro setting that would provide more accurate information about the disease pathophysiology and help design better targeted treatments. We designed a healthy and disease state coculture model that can be induced into a fibroplastic state to overexpress stress fibers using TGFβ1. We also demonstrated that both cell types maintained phenotype in the healthy and disease state coculture models.
To further transfer this model in a physiologically relevant 3D system, follow-up research characterized 3D matrices to mimic the native ECM of the vocal folds by using natural biomimetic materials found in the vocal folds such as hyaluronic acid, type I collagen, and type III collagen. We hypothesized that the ability to control the viscoelastic and structuralcharacteristics of the scaffold in combination with presenting relevant biological cues to cells will result in a better biomimetic scaffold. This research is expected to lay effective groundwork for developing a functional tissue engineered 3D coculture model that retains the reproducibility necessary to serve as a viable diagnostic and therapeutic screening platform.
Changes to the varicella and pertussis immunisation schedule in Germany 2009: Background, rationale and implementation
Creators: name: Wiese-Posselt, Miriam
name: Hellenbrand, Wiebke
Publisher: name: Robert Koch-Institut
Year: 2010
Subjects: subject: Adult
subject: Preschool
subject: Humans
subject: Female
subject: Germany/epidemiology
subject: Male
subject: Incidence
subject: Child
subject: Hospital
subject: Personnel
subject: Infant
subject: Disease Outbreaks/prevention & control
subject: Disease Outbreaks/statistics & numerical data
subject: Comorbidity
subject: Chickenpox/epidemiology
subject: Chickenpox/prevention & control
subject: Caregivers
subject: Chickenpox Vaccine
subject: Child Care/organization & administration
subject: Immunization Schedule
subject: Pertussis Vaccine/administration & dosage
subject: Whooping Cough/epidemiology
subject: Whooping Cough/prevention & control
subject: 610 Medizin

description: In July 2009, the German Standing Committee on Vaccination (STIKO) modified its recommendations for varicella and pertussis vaccination, based on newly available data on disease epidemiology, vaccine effectiveness (VE) and safety, and an evaluation of the feasibility of the recommended immunisation strategy. The recommendation for varicella vaccine now includes a routine two-dose schedule with the administration of the first dose at the age of 11 to 14 months and the second dose at the age of 15 to 23 months, with a minimum interval of four weeks between these doses. Furthermore, STIKO recommended adding a one-time pertussis booster to the adult vaccination schedule to expand the cocoon strategy in place since 2004. The recommendation of a booster vaccination with an acellular pertussis vaccine every 10 years for persons employed in the care of pre-school children and for healthcare personnel in paediatric, gynaecologic and obstetric health facilities was extended to persons employed in schools and in other institutions caring for older children, and to all healthcare personnel. These recommendations were based on available epidemiological data showing an increase in incidence from 7-10 cases per 100,000 inhabitants in 2002-2004 to over 30 by 2007. Moreover, the high burden of pertussis in infants at 94 hospitalised cases per 100,000 infants in 2007 suggested that the previous cocoon strategy was insufficient.
title: Интегралы, их виды и элементы теории поля
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2025

description: В учебном пособии с единой позиции даны понятия кратных, криволинейных и поверхностных интегралов. Кратко изложены элементы теории поля. Теоретический материал сопровождается подробным решением большого количества типовых задач. Приведены варианты домашних контрольных работ. Все задачи снабжены ответами. Приложения содержат основные формулы раздела и графики важнейших кривых и поверхностей. Подготовлено с учетом требований Федерального государственного образовательного стандарта высшего образования. Учебное пособие предназначено для студентов всех специальностей и направлений подготовки, изучающих дисциплину «Математика».
title: Large-scale agricultural investments and local food security – Evidence from a mixed-method case study in Benin
Creators: name: Muder, Anika
name: Luckmann, Jonas
name: Schmid, Julia C.
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: Foreign direct investment
subject: Land acquisition
subject: Land deal
subject: Land grabbing
subject: Land transfer
subject: Livelihood
subject: Q12
subject: Q15
subject: I39
subject: 630 Landwirtschaft und verwandte Bereiche
subject: 640 Hauswirtschaft und Familie
subject: 650 Management und unterstützende Tätigkeiten
subject: 660 Chemische Verfahrenstechnik und verwandte Technologien

description: Large-scale agricultural investments (LSAIs) and their impacts on local communities in host countries have been controversially discussed in recent years. As scholars increasingly call for more structured and comprehensive analyses, we develop a mixed-method approach using an expanded version of the “Right to Food” (RtF) framework to systematically investigate the local food security impacts of a recently established tomato-producing LSAI in Central Benin, West Africa. We find that the LSAI keeps natural resources as accessible as possible for the local community and provides employment opportunities, leading to higher dietary diversity of employees and multiplier effects in the local economy. At the same time, we find inequalities regarding the compensation of former land users as well as high job insecurity for temporary laborers who face high transportation costs to reach the LSAI. We argue that fair and inclusive compensation, improved access to markets and machinery, access to natural resources for often overlooked groups (pastoralists, hunters, fishermen) and social infrastructure are crucial factors in promoting positive outcomes of LSAIs on communities and that strong local institutions play a key role for achieving this. We conclude that the specific characteristics of our case (relatively small size, labor-intensive crop, focus on regional markets) provide favorable conditions for positive impacts on local food security. We encourage further, structured mixed-method studies, ideally including longitudinal and comparative research designs, to investigate the multidimensional effects related to the establishment of LSAIs. The extended RtF framework can thereby serve as a structural lens to systematically analyze the findings.