Additional file 1 of The effect of seasonal and extreme floods on hospitalizations for Legionnaires’ disease in the United States, 2000–2011
Creators: name: Lynch, Victoria D.
name: Shaman, Jeffrey
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: Additional file 1. Legionnaires_Flooding_Supplement. Table S1. Description of HCUP hospitals grouped by Legionnaires’ disease case count thresholds. Table S2. Cyclonic storms that affected counties with HCUP hospitals between 2000 and 2011. Table S3. Percentile of average monthly hospitalizations in months with extreme meteorological conditions averaged across Hospital Service Areas (HSAs) compared to bootstrapped distribution of average monthly hospitalizations. Table S4. Association between Legionnaires’ disease hospitalizations and meteorological variables in the most highly weighted model for each hospitalization threshold. Table S5. Association between Legionnaires’ disease hospitalizations and meteorological variables averaged across Hospital Service Areas (HSAs) in the most highly weighted models. Figure S1. a–b. a Precipitation associated with cyclonic storms and b proximity to the storm track were not associated with a consistent significant change in monthly Legionnaires’ disease hospitalizations among hospitals that experienced the storms, compared to hospitals that were unexposed to the storms. Moderately intense precipitation (quartile 3) was associated with a significant increase in hospitalizations among the hospitals with a minimum of 15 and 20 total cases, but this association was insignificant at different precipitation levels and case thresholds. The analysis was restricted hospitals in regions that experience cyclonic storms from the Atlantic storm basin and to the months of the Atlantic storm season (June–November). Figure S2. a–c The association between exposure to cyclonic storms at the Hospital Service Area (HSA) level of analysis and monthly Legionnaires’ disease hospitalizations did not substantially differ from the associations identified using the county-level storm data. a Among hospitals in the 10-, 15-, and 20-case thresholds, hospitals in HSAs exposed to storms had a significant increase in hospitalizations compared to those in HSAs unexposed to storms. b Cyclonic-storm related precipitation and c proximity to storm tracks at the HSA level were not associated with significant changes in monthly hospitalizations; these findings are consistent with the analyses using county-level storm data (Fig. 2, Additional file 1: Fig. S1). Figure S3. a–d Monthly hydrometeorological flood-indicator variables averaged across the 75 hospitals in the primary analysis between 2000 and 2011, grouped by state (lines) and geographic region (color). The seasonality of a precipitation and c runoff differs in the Northeast and Midwest compared to the Southwest and West Coast, with peaks typically occurring in opposite months of the year. The seasonal pattern of b soil moisture and d streamflow is more consistent across the US, but the magnitude of the seasonal variation differs by region. Model S1. Description of negative binomial generalized mixed model used to assess the effect of cyclonic storms on hospitalizations. Model S2. Description of negative binomial generalized mixed model used to assess the effect of seasonal hydrometeorology and temperature on hospitalizations.