cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Signatures of antagonistic pleiotropy in a bacterial flagellin epitope
Creators: name: Jones, C.D.
name: Sonnleitner, E.
name: Parys, K.
name: Korte, A.
name: Lee, D.
name: Schandry, N.
name: Trgovcevic, A.
name: Hothorn, M.
name: Becker, C.
name: Madalinski, M.
name: Lee, H.-S.
name: Hohmann, U.
name: Blahovska, Z.
name: Muhari-Portik, Z.
name: Rodríguez-Arévalo, I.
name: Mechtler, A.
name: Colaianni, N.R.
name: Belkhadir, Y.
name: Dangl, J.L.
name: Edelbacher, N.
name: Geldner, N.
name: Bläsi, U.
Publisher: name: Cell Press
Year: 2021

description: Immune systems respond to “non-self” molecules termed microbe-associated molecular patterns (MAMPs). Microbial genes encoding MAMPs have adaptive functions and are thus evolutionarily conserved. In the presence of a host, these genes are maladaptive and drive antagonistic pleiotropy (AP) because they promote microbe elimination by activating immune responses. The role AP plays in balancing the functionality of MAMP-coding genes against their immunogenicity is unknown. To address this, we focused on an epitope of flagellin that triggers antibacterial immunity in plants. Flagellin is conserved because it enables motility. Here, we decode the immunogenic and motility profiles of this flagellin epitope and determine the spectrum of amino acid mutations that drives AP. We discover two synthetic mutational tracks that undermine the detection activities of a plant flagellin receptor. These tracks generate epitopes with either antagonist or weaker agonist activities. Finally, we find signatures of these tracks layered atop each other in natural Pseudomonads.
Selective Attention Aids Rapid Learning in Complex Environments
Creators: name: Toutounji, Hazem
name: Merten, Tom
name: Boehme, Nico
name: Hermann, Selina
name: Durstewitz, Daniel
name: Bähner, Florian
Publisher: name: G-Node
Year: 2022
Subjects: Computational Neuroscience
Attention, reward, decision making

description: Bernstein Conference 2022 abstract. http://bernstein-conference.de
ПРАВОВЫЕ ПРОБЛЕМЫ ЗАЩИТЫ ПЕРСОНАЛЬНЫХ ДАННЫХ ПРИ ИНТЕГРАЦИИ ИНТЕРНЕТА ВЕЩЕЙ В ПОВСЕДНЕВНУЮ ЖИЗНЬ
Creators: name: Евгений Юрьевич Семенов
name: Вадим Вячеславович Линьков
Publisher: name: Закон и право
Year: 2020
Subjects: Интернет вещей
Большие данные
облачные вычисления
персональные данные
информация
информационные технологии

description: Статья посвящена проблемам правового регулирования обработки персональных данных при использовании приложений Интернета вещей. Рассматриваются основные направления совершенствования текущего законодательства с учетом тенденций развития современных информационных технологий в части, касающейся массового внедрения «умных» устройств, собирающих и обрабатывающих данные пользователей.
О ПЕРСПЕКТИВАХ ИСПОЛЬЗОВАНИЯ ФЕДЕРАЛЬНОГО РЕГИСТРА СВЕДЕНИЙ О НАСЕЛЕНИИ ОРГАНАМИ ВНУТРЕННИХ ДЕЛ
Creators: name: Валентин Васильевич Авдеев
Publisher: name: Закон и право
Year: 2020
Subjects: Федеральный регистр сведений о населении
органы внутренних дел
идентификация
аутентификация
биометрия

description: В статье рассматриваются перспективы использования Федерального регистра сведений о населении органами внутренних дел. Отмечается необходимость объединения имеющихся информационных ресурсов органов внутренних дел, включения органов внутренних дел в число операторов Единой системы идентификации и аутентификации и Единой биометрической системы. Помимо этого, выявлена необходимость информировать граждан о возможности получения государственных услуг посредством электронного документооборота и его безопасности.
(500322) William Whiting
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A complex immune response to flagellin epitope variation in commensal communities
Creators: name: Belkhadir, Y.
name: Law, T.F.
name: Conway, J.M.
name: Kim, N.H.
name: Jones, C.D.
name: Dangl, J.L.
name: Colaianni, N.R.
name: Mucyn, T.S.
name: Parys, K.
name: Edelbacher, N.
name: Madalinski, M.
name: Lee, H.-S.
Publisher: name: Cell Press
Year: 2021

description: Immune systems restrict microbial pathogens by identifying “non-self” molecules called microbe-associated molecular patterns (MAMPs). It is unclear how immune responses are tuned to or by MAMP diversity present in commensal microbiota. We systematically studied the variability of commensal peptide derivatives of flagellin (flg22), a MAMP detected by plants. We define substantial functional diversity. Most flg22 peptides evade recognition, while others contribute to evasion by manipulating immunity through antagonism and signal modulation. We establish a paradigm of signal integration, wherein the sequential signaling outputs of the flagellin receptor are separable and allow for reprogramming by commensal-derived flg22 epitope variants. Plant-associated communities are enriched for immune evading flg22 epitopes, but upon physiological stress that represses the immune system, immune-activating flg22 epitopes become enriched. The existence of immune-manipulating epitopes suggests that they evolved to either communicate or utilize the immune system for host colonization and thus can influence commensal microbiota community composition.
Representational Drift As a Result of Implicit Regularization
Creators: name: Ratzon, Aviv
name: Khatib, Dorgham
name: Sellevoll, Mariell
name: Morris, Genela
name: Derdikman, Dori
name: Barak, Omri
Publisher: name: G-Node
Year: 2022
Subjects: Computational Neuroscience
Learning, plasticity and memory

description: Bernstein Conference 2022 abstract. http://bernstein-conference.de
M String, Monopole String and Modular Forms
Creators: name: Hohenegger, Stefan
name: Iqbal, Amer
name: Rey, Soo-Jong
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Algebraic Geometry (math.AG)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We study relations between M-strings (one-dimensional intersections of M2-branes and M5-branes) in six dimensions and m-strings (magnetically charged monopole strings) in five dimensions. For specific configurations, we propose that the counting functions of BPS bound-states of M-strings capture the elliptic genus of the moduli space of m-strings. We check this proposal for the known cases, the Taub-NUT and Atiyah-Hitchin spaces for which we find complete agreement. Furthermore, we analyze the modular properties of the M-string free energies, which do not transform covariantly under SL(2,Z). However, for a given number of M-strings, we find that there exists a unique combination of unrefined genus-zero free energies that transforms as a Jacobi form under a congruence subgroup of SL(2,Z). These combinations correspond to summing over different numbers of M5-branes and make sense only if the distances between them are all equal. We explain that this is a necessary condition for the m-string moduli space to be factorizable into relative and center-of-mass parts.
description: 80 pages, 4 embedded figures, 5 long tables; v2. typos fixed; v3. published version with title change
title: Sonic log depth series predictions using machine learning algorithms
Creators: name: Zare, Bahare
Publisher: name: Memorial University of Newfoundland
publisherIdentifier: https://ror.org/04haebc03
publisherIdentifierScheme: ROR
Year: 2024

description: This paper investigates the viability of predicting rock properties within wells using real-time drilling data. Among these properties, the sonic log plays a crucial role in understanding the physical characteristics of subsurface formations and helps geoscientists and drilling engineers interpret the subsurface geology and make informed decisions about well construction, drilling parameters, and reservoir performance. Successfully forecasting sonic logs has the potential to significantly improve the optimization of fracturing processes in wells with similar geological structures. To accomplish this objective, we introduced a well-structured eXtreme Gradient Boosting (XGBoost), LSTM (Long Short-Term Memory), and Random Forest (RF) models that utilize depth-series data for predicting sonic log in the field of oil and gas exploration. The data used in this research was gathered from the drilling project “A Data Analytics Approach to Energy and Safety Improvements” which received funding from the NL Offshore Oil and Gas Industry Recovery Assistance Fund.
(500323) George Moberly
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supnorm of Modular Forms of half-integral Weight in the Weight Aspect
Creators: name: Steiner, Raphael S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11F37

description: We bound the supnorm of half-integral weight Hecke eigenforms in the Kohnen plus space of level $4$ in the weight aspect, by combining bounds obtained from the Fourier expansion with the amplification method using a Bergman kernel.
description: 13 pages
ANALYZING DALFAMPRIDINE'S POTENTIAL FOR PROLONGED RELEASE AS A MATRIX TABLET USING VARIOUS GRADES OF HPMC AND EUDRAGIT
Creators: name: M Ameer Khan1, Niranjan Panda1*, Sameera Fatima2, Ayesha Farhath Fathima3
Publisher: name: Zenodo
Year: 2024

description: Present studies aimed to formulate a once-daily sustained-release matrix tablet of Dalfampridine to reduce the frequency of administration and improve patient compliance. Multiple sclerosis patients who have trouble walking can benefit from dalfampridine. Dalfampridine is taken orally twice daily in doses of 10 mg, with a plasma half-life of 5.2 to 6.5 hours. A once-daily sustained-release version of dalfampridine is preferred to lessen administration frequency and boost patient compliance. BCS Class I chemical with high solubility, high permeability, and pH-independent solubility. Using hydrophilic synthetic polymers like hydroxyl propyl methyl cellulose (HPMC K4M & HPMC K15M) and hydrophobic synthetic polymers like Eudragit RSPO and RLPO, the current work sought to evaluate and improve sustained released Dalfampridine matrix tablets. To improve the release rate for a once-daily drug, a matrix tablet containing dalfampridine was created using the wet granulation process at various ratios of HPMC and Eudragit. Utilizing a USP type-II paddle type eight station dissolving device, an in vitro release investigation was carried out. To confirm the drug's compatibility with polymers, FTIR and DSC studies were conducted. Different pre- and post-compression characterizations of the tablet were conducted, and the results complied with pharmacopeia requirements. Accelerated stability experiments were done to confirm the stability of the dosage formulations.

Key Words: Sustained release tablet, Dalfampridine, Matrix tablets, HPMC, Eudragit.
Latent Equilibrium: A unified learning theory for arbitrarily fast computation with arbitrarily slow neurons
Creators: name: Haider, Paul
name: Ellenberger, Benjamin
name: Kriener, Laura
name: Jordan, Jakob
name: Senn, Walter
name: Petrovici, Mihai A.
Publisher: name: G-Node
Year: 2022
Subjects: Computational Neuroscience
Learning, plasticity and memory

description: Bernstein Conference 2022 abstract. http://bernstein-conference.de
The Use of Integrative Motivation in EFL Reading Skills: A Case Study of Tertiary-level Thai University Students
Creators: name: Nipaporn Chalermnirundorn
Publisher: name: ศูนย์สนับสนุนและพัฒนาการเรียนการสอน มหาวิทยาลัยรังสิต
Year: 2016
Subjects: Integrative Motivation
Reading Motivation
Reading Proficiency
Reading Skills
Tertiary Level Education
การศึกษาระดับ
ความสามารถในการอ่าน
ทักษะด้านการอ่าน
อุดมศึกษา
แรงจูงใจแบบบูรณาการ
แรงจูงใจในการอ่าน

description: วารสารพัฒนาการเรียนการสอน, 10, 1, 47-76
CSCCE Community Manager Case Study: Connie Clare
Creators: name: Clare, Connie
name: Pratt, Katie
name: Sidik, Saima
name: Woodley, Lou
Publisher: name: Zenodo
Year: 2022
Subjects: CSCCE
CSCCE Community Manager Case Study
scientific community manager
4TU.ResearchData

description: This case study features Connie Clare, Community Manager at 4TU.ResearchData. It is part of an ongoing collection created by the Center for Scientific Collaboration and Community Engagement. It is part of our research into the nature of community manager roles and how they vary across the STEM ecosystem. You can find out more about the project, and view additional case studies in the collection, on our website. To find the case studies on Zenodo, click here. About CSCCE The Center for Scientific Collaboration and Community Engagement (CSCCE) champions the importance of human infrastructure for effective collaboration in STEM. We provide training and support for the people who make scientific collaborations succeed at scale - and we also research the impact of these emerging roles. Find out more about us on our website: CSCCE.org.
เกมคอมพิวเตอร์เพื่อส่งเสริมการใช้ยาปฏิชีวนะอย่างสมเหตุสมผลในนักศึกษาเภสัชศาสตร์ชั้นปีที่ 1 - 6
Creators: name: ภัทรวิท สรรพคุณ
Publisher: name: ศูนย์สนับสนุนและพัฒนาการเรียนการสอน มหาวิทยาลัยรังสิต
Year: 2016
Subjects: Antibiotics Smart Use
Computer Game
Pharmacy
Pharmacy Student
การใช้ยาปฏิชีวนะอย่างสมเหตุสมผล
นักศึกษาเภสัชศาสตร์
เกมคอมพิวเตอร์
เภสัชศาสตร์

description: วารสารพัฒนาการเรียนการสอน, 10, 1, 77-85
(500317) William Corfe
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Plant “helper” immune receptors are Ca2+-permeable nonselective cation channels
Creators: name: Wu, F.
name: Redinbo, M.R.
name: El-Kasmi, F.
name: Pei, Z.-M.
name: Kempthorn, K.
name: Dangl, J.L.
name: Furzer, O.J.
name: Jacob, P.
name: Kim, N.H.
name: Wan, L.
name: Walton, W.G.
name: Lietzan, A.D.
name: Sunil, S.
name: Chi, Y.
Publisher: name: American Association for the Advancement of Science
Year: 2021

description: Plant nucleotide-binding leucine-rich repeat receptors (NLRs) regulate immunity and cell death. In Arabidopsis, a subfamily of “helper” NLRs is required by many “sensor” NLRs. Active NRG1.1 oligomerized, was enriched in plasma membrane puncta, and conferred cytoplasmic calcium ion (Ca2+) influx in plant and human cells. NRG1.1-dependent Ca2+ influx and cell death were sensitive to Ca2+ channel blockers and were suppressed by mutations affecting oligomerization or plasma membrane enrichment. Ca2+ influx and cell death mediated by NRG1.1 and ACTIVATED DISEASE RESISTANCE 1 (ADR1), another helper NLR, required conserved negatively charged N-terminal residues. Whole-cell voltage-clamp recordings demonstrated that Arabidopsis helper NLRs form Ca2+-permeable cation channels to directly regulate cytoplasmic Ca2+ levels and consequent cell death. Thus, helper NLRs transduce cell death signals directly.
Coordination between microbiota and root endodermis supports plant mineral nutrient homeostasis
Creators: name: Salt, D.E.
name: Gopaulchan, D.
name: Dangl, J.L.
name: Bakhoum, N.
name: Dew, T.P.
name: Castrillo, G.
name: Franke, R.B.
name: Reyt, G.
name: Flis, P.
name: Suresh, K.
name: Salas-González, I.
name: Custódio, V.
Publisher: name: American Association for the Advancement of Science
Year: 2021

description: Plant roots and animal guts have evolved specialized cell layers to control mineral nutrient homeostasis. These layers must tolerate the resident microbiota while keeping homeostatic integrity. Whether and how the root diffusion barriers in the endodermis, which are critical for the mineral nutrient balance of plants, coordinate with the microbiota is unknown. We demonstrate that genes controlling endodermal function in the model plant Arabidopsis thaliana contribute to the plant microbiome assembly. We characterized a regulatory mechanism of endodermal differentiation driven by the microbiota with profound effects on nutrient homeostasis. Furthermore, we demonstrate that this mechanism is linked to the microbiota's capacity to repress responses to the phytohormone abscisic acid in the root. Our findings establish the endodermis as a regulatory hub coordinating microbiota assembly and homeostatic mechanisms.
The EDS1–PAD4–ADR1 node mediates Arabidopsis pattern-triggered immunity
Creators: name: Rao, S.
name: Saile, S.C.
name: Joe, A.
name: Stolze, S.C.
name: Joosten, M.H.A.J.
name: Wan, W.-L.
name: Harzen, A.
name: Nürnberger, T.
name: Kasmi, F.E.
name: Hu, M.
name: Gust, A.A.
name: Thomma, B.P.H.J.
name: Karelina, D.
name: Hua, C.
name: Pruitt, R.N.
name: Locci, F.
name: Oecking, C.
name: Nakagami, H.
name: Weigel, D.
name: Parker, J.E.
name: Zhou, J.-M.
name: Harter, K.
name: Zhang, L.
name: Wanke, F.
name: Dangl, J.L.
name: Fröhlich, K.
Publisher: name: Nature Research
Year: 2021

description: Plants deploy cell-surface and intracellular leucine rich-repeat domain (LRR) immune receptors to detect pathogens1. LRR receptor kinases and LRR receptor proteins at the plasma membrane recognize microorganism-derived molecules to elicit pattern-triggered immunity (PTI), whereas nucleotide-binding LRR proteins detect microbial effectors inside cells to confer effector-triggered immunity (ETI). Although PTI and ETI are initiated in different host cell compartments, they rely on the transcriptional activation of similar sets of genes2, suggesting pathway convergence upstream of nuclear events. Here we report that PTI triggered by the Arabidopsis LRR receptor protein RLP23 requires signalling-competent dimers of the lipase-like proteins EDS1 and PAD4, and of ADR1 family helper nucleotide-binding LRRs, which are all components of ETI. The cell-surface LRR receptor kinase SOBIR1 links RLP23 with EDS1, PAD4 and ADR1 proteins, suggesting the formation of supramolecular complexes containing PTI receptors and transducers at the inner side of the plasma membrane. We detected similar evolutionary patterns in LRR receptor protein and nucleotide-binding LRR genes across Arabidopsis accessions; overall higher levels of variation in LRR receptor proteins than in LRR receptor kinases are consistent with distinct roles of these two receptor families in plant immunity. We propose that the EDS1–PAD4–ADR1 node is a convergence point for defence signalling cascades, activated by both surface-resident and intracellular LRR receptors, in conferring pathogen immunity.
(500319) Wm Twinch Bracewell
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Quasilattice-conserved optimization of the atomic structure of decagonal Al-Co-Ni quasicrystals
Creators: name: Li, Xiao-Tian
name: Yang, Xiao-Bao
name: Zhao, Yu-Jun
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The detailed atomic structure of quasicrystals has been an open question for decades. Here, we present a quasilattice-conserved optimization method (quasiOPT), with particular quasiperiodic boundary conditions. As the atomic coordinates described by basic cells and quasilattices, we are able to maintain the self-similarity characteristics of qusicrystals with the atomic structure of the boundary region updated timely following the relaxing region. Exemplified with the study of decagonal Al-Co-Ni (d-Al-Co-Ni), we propose a more stable atomic structure model based on Penrose quasilattice and our quasiOPT simulations. In particular, "rectangle-triangle" rules are suggested for the local atomic structures of d-Al-Co-Ni quasicrystals.
บุคลิกภาพที่พึงประสงค์ของนักศึกษาสถาบันการบินสำหรับโรงเรียนการบิน
Creators: name: ศุภกฤต อริยะปรีชา
Publisher: name: ศูนย์สนับสนุนและพัฒนาการเรียนการสอน มหาวิทยาลัยรังสิต
Year: 2016
Subjects: Aviation Institute Students
Flying Training Schools
Personality
นักศึกษาสถาบันการบิน
บุคลิกภาพ
โรงเรียนการบิน

description: วารสารพัฒนาการเรียนการสอน, 10, 1, 86-94
ประสิทธิผลของสื่อการสอนอิเล็กทรอนิกส์รายวิชา THA 106 ภาษาไทยเพื่อการสื่อสาร เรื่อง การพูด
Creators: name: สุกัลยา วงศ์ชมบุญ
Publisher: name: ศูนย์สนับสนุนและพัฒนาการเรียนการสอน มหาวิทยาลัยรังสิต
Year: 2016
Subjects: e-Learning Courseware
Learning Achievement
Speaking
Thai Language for Communication
การพูด
ผลสัมฤทธิ์ทางการเรียน
ภาษาไทยเพื่อการสื่อสาร
สื่อการสอนอิเล็กทรอนิกส์

description: วารสารพัฒนาการเรียนการสอน, 10, 1, 95-102
(500320) William David Bracewell
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Learning Contour-Fragment-based Shape Model with And-Or Tree Representation
Creators: name: Lin, Liang
name: Wang, Xiaolong
name: Yang, Wei
name: Lai, Jianhuang
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences
subject: 68U01

description: This paper proposes a simple yet effective method to learn the hierarchical object shape model consisting of local contour fragments, which represents a category of shapes in the form of an And-Or tree. This model extends the traditional hierarchical tree structures by introducing the "switch" variables (i.e. the or-nodes) that explicitly specify production rules to capture shape variations. We thus define the model with three layers: the leaf-nodes for detecting local contour fragments, the or-nodes specifying selection of leaf-nodes, and the root-node encoding the holistic distortion. In the training stage, for optimization of the And-Or tree learning, we extend the concave-convex procedure (CCCP) by embedding the structural clustering during the iterative learning steps. The inference of shape detection is consistent with the model optimization, which integrates the local testings via the leaf-nodes and or-nodes with the global verification via the root-node. The advantages of our approach are validated on the challenging shape databases (i.e., ETHZ and INRIA Horse) and summarized as follows. (1) The proposed method is able to accurately localize shape contours against unreliable edge detection and edge tracing. (2) The And-Or tree model enables us to well capture the intraclass variance.
description: 8 pages, 7 figures, CVPR 2012
Strong recurrency of cortical networks constrains activity in low-dimensional subspaces
Creators: name: Dahmen, David
name: Recanatesi, Stefano
name: Jia, Xiaoxuan
name: Ocker, Gabriel K.
name: Campagnola, Luke
name: Jarsky, Tim
name: Seeman, Stephanie
name: Helias, Moritz
name: Shea-Brown, Eric
Publisher: name: G-Node
Year: 2022
Subjects: Computational Neuroscience
Networks, dynamical systems

description: Bernstein Conference 2022 abstract. http://bernstein-conference.de
Specific modulation of the root immune system by a community of commensal bacteria
Creators: name: Law, T.F.
name: Gilbert, S.
name: Li, H.
name: Del Risco, N.M.
name: Castrillo, G.
name: Jones, C.D.
name: Finkel, O.M.
name: Mieczkowski, P.
name: Panda, D.
name: Teixeira, P.J.P.L.
name: Colaianni, N.R.
name: Salas-González, I.
name: Conway, J.M.
name: Dangl, J.L.
Publisher: name: National Academy of Sciences
Year: 2021

description: Plants have an innate immune system to fight off potential invaders that is based on the perception of nonself or modified-self molecules. Microbe-associated molecular patterns (MAMPs) are evolutionarily conserved microbial molecules whose extracellular detection by specific cell surface receptors initiates an array of biochemical responses collectively known as MAMP-triggered immunity (MTI). Well-characterized MAMPs include chitin, peptidoglycan, and flg22, a 22-amino acid epitope found in the major building block of the bacterial flagellum, FliC. The importance of MAMP detection by the plant immune system is underscored by the large diversity of strategies used by pathogens to interfere with MTI and that failure to do so is often associated with loss of virulence. Yet, whether or how MTI functions beyond pathogenic interactions is not well understood. Here we demonstrate that a community of root commensal bacteria modulates a specific and evolutionarily conserved sector of the Arabidopsis immune system. We identify a set of robust, taxonomically diverse MTI suppressor strains that are efficient root colonizers and, notably, can enhance the colonization capacity of other tested commensal bacteria. We highlight the importance of extracellular strategies for MTI suppression by showing that the type 2, not the type 3, secretion system is required for the immunomodulatory activity of one robust MTI suppressor. Our findings reveal that root colonization by commensals is controlled by MTI, which, in turn, can be selectively modulated by specific members of a representative bacterial root microbiota.
การวิเคราะห์ธรรมชาติของเนื้อหาชีววิทยาด้วยคำถาม 3 ข้อเพื่อการออกแบบการเรียนการสอน วิชาชีววิทยา: กรณีตัวอย่าง เรื่อง เซลล์ประสาท
Creators: name: สิทธิชัย วิชัยดิษฐ
Publisher: name: ศูนย์สนับสนุนและพัฒนาการเรียนการสอน มหาวิทยาลัยรังสิต
Year: 2016
Subjects: 5E Instructional Model
Biological Forms and Functions
Multiple Representations
Nature of Science
การนำเสนอที่หลากหลาย
ธรรมชาติของวิทยาศาสตร์
รูปแบบการจัดการเรียนรู้ แบบ 5E
โครงสร้างและหน้าที่ของสิ่งมีชีวิต

description: วารสารพัฒนาการเรียนการสอน, 10, 1, 103-117
Dopamine-mediated cellular programming of heuristic decisions
Creators: name: Jung, Kanghoon
name: Burke, Benjamin
name: Schappaugh, Nicholas
name: Kwon, Hyung-Bae
Publisher: name: G-Node
Year: 2022
Subjects: Computational Neuroscience
Learning, plasticity and memory

description: Bernstein Conference 2022 abstract. http://bernstein-conference.de
A host target of a bacterial cysteine protease virulence effector plays a key role in convergent evolution of plant innate immune system receptors
Creators: name: Sohn, K.H.
name: Dangl, J.L.
name: Chung, E.-H.
name: Won, K.
name: Prokchorchik, M.
name: Choi, S.
Publisher: name: Blackwell Publishing Ltd
Year: 2020

description: Some virulence effectors secreted from pathogens target host proteins and induce biochemical modifications that are monitored by nucleotide-binding and leucine-rich repeat (NLR) immune receptors. Arabidopsis RIN4 protein (AtRIN4: RPM1-interacting protein 4) homologs are present in diverse plant species and targeted by several bacterial type III effector proteins including the cysteine protease AvrRpt2. RIN4 is ‘guarded’ by several independently evolved NLRs from various plant species, including Arabidopsis RPS2. Recently, it was shown that the MR5 NLR from a wild apple relative can recognize the AvrRpt2 effector from Erwinia amylovora, but the details of this recognition remained unclear. The present contribution reports the mechanism of AvrRpt2 recognition by independently evolved NLRs, MR5 from apple and RPS2, both of which require proteolytically processed RIN4 for activation. It shows that the C-terminal cleaved product of apple RIN4 (MdRIN4) but not AtRIN4 is necessary and sufficient for MR5 activation. Additionally, two polymorphic residues in AtRIN4 and MdRIN4 are identified that are crucial in the regulation of and physical association with NLRs. It is proposed that polymorphisms in RIN4 from distantly related plant species allow it to remain an effector target while maintaining compatibility with multiple NLRs.
เด็กปฐมวัยเรียนรู้ผ่านการเล่น: ประเด็นที่ครูต้องให้ความสำคัญ
Creators: name: อรุณี หรดาล
Publisher: name: ศูนย์สนับสนุนและพัฒนาการเรียนการสอน มหาวิทยาลัยรังสิต
Year: 2016
Subjects: learning through play
preschool children
การเรียนรู้ผ่านการเล่น
เด็กปฐมวัย

description: วารสารพัฒนาการเรียนการสอน, 10, 1, 118-129
(500316) Louis Rt Jas. Versturm
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Where Lies the State? Sāmoa's 2021 Election and the Defeat of the Human Rights Protection Party
Creators: name: Fraenkel, Jonathan
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2023
Subjects: subject: Anthropology
subject: FOS: Sociology
subject: 169999 Studies in Human Society not elsewhere classified
subject: 210399 Historical Studies not elsewhere classified
subject: FOS: History and archaeology

description: In 2021, Sāmoa witnessed its first change of government since the 1980s. The April election result entailed a narrow defeat for the governing Human Rights Protection Party (HRPP). This triggered a major constitutional crisis and a succession of legal battles over the 10 per cent quota for women in parliament and over the powers of the head of state, who had attempted to cancel the election. This paper examines the election outcome, how this was influenced by changing electoral laws, and why the newly formed Fa‘atuatua I Le Atua Samoa ua Tasi (FAST) party was able to mount such a strong challenge to the HRPP. The paper argues that the central issue during the campaign–the HRPP's reforms to reconfigure the Land and Titles Court–was not (as widely depicted) a dispute over ‘communal' versus ‘individual rights’ but rather one over two conflicting visions of centralized control.
title: Clubbing: otherness and the politics of experience
Creators: name: Rief, Silvia
Publisher: name: Goldsmiths, University of London
Year: 2003

description: This thesis investigates experiences of contemporary club and dance cultures in the context of postmodern aestheticisation. Its object of study is the phantasmatic and discursive complex of otherness, transgression and freedom in which contemporary British club and dance cultures are embedded. It argues that clubbing experiences are fabricated through this complex of otherness, which articulates a politics, of experience. This refers to contexts that structure experiences of dance cultures. In this respect, the thesis considers the contexts of class, gender and sexuality, structures of the production and consumption of clubbing, the institutional regulation and ordering of club spaces and media discourses and imagery. In analysing socially contextualised meanings of this otherness it examines how these become relevant for the construction of identity. The theoretical agenda of the thesis is to explore aestheticisation as a condition for and as a form of identity construction. This engages with changing modes of reflexivity in the construction of reality and reformulates the issues of style, identity and authenticity. The empirical analysis focuses on modes of reflexivity in constructing realities of sexuality, body and self. Research of this study was carried out in London. The qualitative research design comprised narrative interviewing and ethnographic participation in clubs in central London. A criterion for sampling and for the selection of clubs and interviewees was the dimension of sexuality and the sexual differentiation and codification of club spaces. The interview sample consists of twenty-three interviews with people of mixed genders, sexualities and cultural, national backgrounds.
(500318) Margaret Wynne
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Lorentz violation in the gravity sector: The t puzzle
Creators: name: Bonder, Yuri
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Lorentz violation is a candidate quantum-gravity signal, and the Standard-Model Extension (SME) is a widely used parametrization of such a violation. In the gravitational SME sector, there is an elusive coefficient for which no effects have been found. This is known as the $t$ puzzle and, to date, it has no compelling explanation. This paper analyzes whether there is a fundamental explanation for the $t$ puzzle. To tackle this question, several approaches are followed. Mainly, redefinitions of the dynamical fields are studied, showing that other SME coefficients can be moved to nongravitational sectors. It is also found that the gravity SME sector can be consistently treated \textit{à la} Palatini, and that, in the presence of spacetime boundaries, it is possible to correct its action to get the desired equations of motion. Moreover, through a reformulation as a Lanczos-type tensor, some problematic features of the $t$ term, which should arise at the phenomenological level, are revealed. The most important conclusion of the paper is that there is no evidence of a fundamental explanation for the $t$ puzzle, suggesting that it may be linked to the approximations taken at the phenomenological level.
CRAGE-Duet Facilitates Modular Assembly of Biological Systems for Studying Plant-Microbe Interactions
Creators: name: Ono, K.
name: Zhao, Z.
name: Wang, B.
name: Wang, G.
name: Dangl, J.L.
name: Yoshikuni, Y.
name: Conway, J.M.
name: Zhang, Z.
name: Cheng, J.-F.
name: Chiniquy, D.M.
name: Jabusch, L.K.
name: Robinson, D.
name: Northen, T.R.
Publisher: name: American Chemical Society
Year: 2020

description: Developing sustainable agricultural practices will require increasing our understanding of plant-microbe interactions. To study these interactions, new genetic tools for manipulating nonmodel microbes will be needed. To help meet this need, we recently reported development of chassis-independent recombinase-assisted genome engineering (CRAGE). CRAGE relies on cassette exchange between two pairs of mutually exclusive lox sites and allows direct, single-step chromosomal integration of large, complex gene constructs into diverse bacterial species. We then extended CRAGE by introducing a third mutually exclusive lox site, creating CRAGE-Duet, which allows modular integration of two constructs. CRAGE-Duet offers advantages over CRAGE, especially when a cumbersome recloning step is required to build single-integration constructs. To demonstrate the utility of CRAGE-Duet, we created a set of strains from the plant-growth-promoting rhizobacterium Pseudomonas simiae WCS417r that expressed various fluorescence marker genes. We visualized these strains simultaneously under a confocal microscope, demonstrating the usefulness of CRAGE-Duet for creating biological systems to study plant-microbe interactions.
title: Deutschlands zirkuläre Zukunft:  Wie Missionen die Transformation  zur Circular Economy beschleunigen
Creators: name: Hummler, Andreas
name: Lindner, Ralf
name: Posch, Daniel
name: Wilts, Henning
name: Wittmann, Florian
name: Wurm, Daniel
Publisher: name: Bertelsmann Stiftung
Year: 2023
Subjects: subject: Kreislaufwirtschaft
subject: Kreislaufökonomie
subject: Transformation
subject: Missionsorientierte Politik
subject: Nachhaltigkeit

description: Um langfristig wettbewerbsfähig zu bleiben und ressourceneffizient sowie klimaneutral zu wirtschaften, braucht es in Deutschland die Transformation zur Kreislaufwirtschaft. Allerdings hat man hierzulande in den vergangenen zwei Jahrzehnten die einstige Vorreiterstellung in diesem Bereich eingebüßt. Auf politischer Seite existieren diverse strategische Ansätze, um hierauf zu reagieren. Jedoch mangelt es an einer ressort- und sektorübergreifenden strategischen Abstimmung und an einer Konkretion der Umsetzungspläne. Das Focus Paper zeigt auf, wie sich diese Schwachstellen durch einen Missionsorientierten Politikansatz adressieren ließen. Insbesondere sollten die politischen Akteure stärker als bislang kooperieren und gemeinsam verbindliche Ziele mit hoher gesellschaftlicher Relevanz definieren. Ebenso müssen bereits während des Missionsformulierungsprozesses die Steuerungs- und Umsetzungsmechanismen mitgedacht werden. Auch werden beispielhafte Vertiefungen für Kreislaufwirtschaftsmissionen aufgezeigt (bspw. in den Bereichen Batterietechnik, Bauwirtschaft und Chemisches Recycling).
Two unequally redundant "helper" immune receptor families mediate Arabidopsis thaliana intracellular "sensor" immune receptor functions
Creators: name: Jacob, P.
name: Dangl, J.L.
name: Jubic, L.M.
name: Saile, S.C.
name: Salas-Gonzáles, I.
name: El Kasmi, F.
name: Bäcker, M.
name: Jones, J.D.G.
name: Castel, B.
Publisher: name: Public Library of Science
Year: 2020

description: Plant nucleotide-binding (NB) leucine-rich repeat (LRR) receptor (NLR) proteins function as intracellular immune receptors that perceive the presence of pathogen-derived virulence proteins (effectors) to induce immune responses. The 2 major types of plant NLRs that "sense"pathogen effectors differ in their N-terminal domains: these are Toll/interleukin-1 receptor resistance (TIR) domain-containing NLRs (TNLs) and coiled-coil (CC) domain-containing NLRs (CNLs). In many angiosperms, the RESISTANCE TO POWDERY MILDEW 8 (RPW8)-CC domain containing NLR (RNL) subclass of CNLs is encoded by 2 gene families, ACTIVATED DISEASE RESISTANCE 1 (ADR1) and N REQUIREMENT GENE 1 (NRG1), that act as "helper"NLRs during multiple sensor NLR-mediated immune responses. Despite their important role in sensor NLR-mediated immunity, knowledge of the specific, redundant, and synergistic functions of helper RNLs is limited. We demonstrate that the ADR1 and NRG1 families act in an unequally redundant manner in basal resistance, effector-triggered immunity (ETI) and regulation of defense gene expression. We define RNL redundancy in ETI conferred by some TNLs and in basal resistance against virulent pathogens. We demonstrate that, in Arabidopsis thaliana, the 2 RNL families contribute specific functions in ETI initiated by specific CNLs and TNLs. Time-resolved whole genome expression profiling revealed that RNLs and "classical"CNLs trigger similar transcriptome changes, suggesting that RNLs act like other CNLs to mediate ETI downstream of sensor NLR activation. Together, our genetic data confirm that RNLs contribute to basal resistance, are fully required for TNL signaling, and can also support defense activation during CNL-mediated ETI.
(500311) Robert Moody
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Uncertainty-modulated prediction errors in cortical microcircuits
Creators: name: Wilmes, Katharina A.
name: Raltchev, Constanze
name: Kasavica, Sergej
name: Petrovici, Mihai A.
name: Sachidhanandam, Shankar
name: Senn, Walter
Publisher: name: G-Node
Year: 2022
Subjects: Computational Neuroscience
Learning, plasticity and memory

description: Bernstein Conference 2022 abstract. http://bernstein-conference.de
The Plant Microbiome: From Ecology to Reductionism and beyond
Creators: name: Conway, J.M.
name: Fitzpatrick, C.R.
name: Dangl, J.L.
name: Gilbert, S.
name: Russ, D.
name: Finkel, O.M.
name: Salas-González, I.
name: Teixeira, P.J.P.L.
Publisher: name: Annual Reviews Inc.
Year: 2020

description: Methodological advances over the past two decades have propelled plant microbiome research, allowing the field to comprehensively test ideas proposed over a century ago and generate many new hypotheses. Studying the distribution of microbial taxa and genes across plant habitats has revealed the importance of various ecological and evolutionary forces shaping plant microbiota. In particular, selection imposed by plant habitats strongly shapes the diversity and composition of microbiota and leads to microbial adaptation associated with navigating the plant immune system and utilizing plant-derived resources. Reductionist approaches have demonstrated that the interaction between plant immunity and the plant microbiome is, in fact, bidirectional and that plants, microbiota, and the environment shape a complex chemical dialogue that collectively orchestrates the plant microbiome. The next stage in plant microbiome research will require the integration of ecological and reductionist approaches to establish a general understanding of the assembly and function in both natural and managed environments.
Excitation Conditions in the Multi-component Submillimeter Galaxy SMM J00266+1708
Creators: name: Sharon, Chelsea E.
name: Baker, Andrew J.
name: Harris, Andrew I.
name: Tacconi, Linda J.
name: Lutz, Dieter
name: Longmore, Steven N.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present multiline CO observations of the complex submillimeter galaxy SMM J00266+1708. Using the Zpectrometer on the Green Bank Telescope, we provide the first precise spectroscopic measurement of its redshift (z=2.742). Based on followup CO(1-0), CO(3-2), and CO(5-4) mapping, SMM J00266+1708 appears to have two distinct components separated by ~500 km/s that are nearly coincident along our line of sight. The two components show hints of different kinematics, with the blue-shifted component dispersion-dominated and the red-shifted component showing a clear velocity gradient. CO line ratios differ slightly between the two components, indicating that the physical conditions in their molecular gas may not be alike. We tentatively infer that SMM J00266+1708 is an ongoing merger with a mass ratio of (7.8+/-4.0)/sin^2(i), with its overall size and surface brightness closely resembling that of other merging systems. We perform large velocity gradient modeling of the CO emission from both components and find that each component's properties are consistent with a single phase of molecular gas (i.e., a single temperatures and density); additional multi-phase modeling of the red-shifted component, although motivated by a CO(1-0) size larger than the CO(3-2) size, is inconclusive. SMM J00266+1708 provides evidence of early stage mergers within the submillimeter galaxy population. Continuum observations of J00266 at the ~1" resolution of our observations could not have distinguished between the two components due to their separation (0.73" +/- 0.06"), illustrating that the additional velocity information provided by spectral line studies is important for addressing the prevalence of unresolved galaxy pairs in low-resolution submillimeter surveys.
description: ApJ accepted, 23 pages, 19 figures
Simulations Approaching Data: Cortical Slow Waves in Inferred Models of the Whole Hemisphere of Mouse
Creators: name: Capone, Cristiano
name: De Luca, Chiara
name: De Bonis, Giulia
name: Gutzen, Robin
name: Bernava, Irene
name: Pastorelli, Elena
name: Simula, Francesco
name: Lupo, Cosimo
name: Tonielli, Leonardo
name: Resta, Francesco
name: Allegra Mascaro, Anna Letizia
name: Pavone, Francesco
name: Denker, Michael
name: Paolucci, Pier Stanislao
Publisher: name: G-Node
Year: 2022
Subjects: Computational Neuroscience
Data analysis, machine learning, neuroinformatics

description: Bernstein Conference 2022 abstract. http://bernstein-conference.de