cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Boundary Layers of Circumplanetary Disks around Spinning Planets I. Effects of Rossby Waves
Creators: name: Fu, Zhihao
name: Huang, Shunquan
name: Yu, Cong
Publisher: name: arXiv
Year: 2022
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Gas giant planets are believed to accrete from their circumplanetary disks (CPDs). The CPDs usually involve accretion through the boundary layer (BL) in the vicinity of planets. Prior studies have concentrated on the BL of non-spinning planets. We investigate the influence of planetary spin on the wave behaviors within the BL. The rotation profile in such BLs would show sharp transition from the rigid rotation to the Keplerian rotation. We examine the angular momentum transport in these BL in terms of linear perturbation analysis. We find that the global inertia-acoustic mode associated with spinning planets would give rise to the inflow of angular momentum and the accretion of gas. In this work, we identify a new kind of global mode, namely the Rossby mode. The Rossby mode can lead to the outflow of angular momentum and the decretion of gas from a spinning planet. The Rossby mode provide a negative feedback that regulates the planetary spin and mass. We compare the growth rate of the two modes as a function of the width of BL, the Mach number and the spin rate of planet. Our results reveal the underlying hydrodynamic mechanism of terminal spins and asymptotic mass of the giant planets.
description: 13 pages, 11 figures, 1 table, with minor revision and resubmitted to ApJ
THE ANALYSIS OF THAI STUDENTS DETERMINANT TO STUDY IN THE UNITED STATES OF AMERICA AND THE UNITED KINGDOM
Creators: name: Hatairat Lertjanyakit
Publisher: name: University of the Thai Chamber of Commerce
Year: 2016
Subjects: Study in the United Kingdom
Study in the United States of America
Higher Education Institution
Study abraod
Thai students
Education in Thailand

description: UTCC International Journal of Business and Economics, 8, 2, 59-75
Liquid ropes: a geometrical model for thin viscous jets instabilities
Creators: name: Brun, P. -T.
name: Audoly, Basile
name: Ribe, Neil M.
name: Eaves, Tom S.
name: Lister, John R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: Thin viscous fluid threads falling onto a moving belt behave in a way reminiscent of a sewing machine, generating a rich variety of periodic stitch-like patterns including meanders, W-patterns, alternating loops, and translated coiling. These patterns form to accommodate the difference between the belt speed and the terminal velocity at which the falling thread strikes the belt. Using direct numerical simulations, we show that inertia is not required to produce the aforementioned patterns. We introduce a quasi-static geometrical model which captures the patterns, consisting of three coupled ODEs for the radial deflection, the orientation and the curvature of the path of the thread's contact point with the belt. The geometrical model reproduces well the observed patterns and the order in which they appear as a function of the fall height.
Global dynamics of GDP and trade
Creators: name: Kakkad, Abhin
name: Ray, Arnab K.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Physics and Society (physics.soc-ph)
subject: General Economics (econ.GN)
subject: FOS: Physical sciences
subject: FOS: Economics and business

description: We use the logistic equation to model the dynamics of the GDP and the trade of the six countries with the highest GDP in the world, namely, USA, China, Japan, Germany, UK and India. From the modelling of the economic data, which are made available by the World Bank, we predict the maximum values of the growth of GDP and trade, as well as the duration over which exponential growth can be sustained. We set up the correlated growth of GDP and trade as the phase solutions of an autonomous second-order dynamical system. GDP and trade are related to each other by a power law, whose exponent seems to differentiate the six national economies into two types. Under conducive conditions for economic growth, our conclusions have general validity.
description: 8 pages, 12 figures, ReVTeX double column format
THE IMPACT OF HUMAN RESOURCE ACCOUNTING INFORMATION SYSTEM (HRAIS) ON HUMAN RESOURCE MANAGEMENT PRACTICES OF THE BANKING SECTOR IN BANGLADESH
Creators: name: Alam, Jahangir
Publisher: name: University of the Thai Chamber of Commerce
Year: 2016
Subjects: Human Resource Department (HRD)
HR executives
Human Resource Planning
Human Resources Accounting (HRA)
Human Resources Accounting Information System (HRAIS)

description: UTCC International Journal of Business and Economics, 8, 2, 77-90
Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases.
Creators: name: Cade, R
name: Gartner, A
name: Zhou, Z
name: Ammerer, G
name: Errede, B
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Protein phosphorylation plays an important role in pheromone-induced differentiation processes of haploid yeast cells. Among the components necessary for signal transduction are the STE7 and STE11 kinases and either one of the redundant FUS3 and KSS1 kinases. FUS3 and presumably KSS1 are phosphorylated and activated during pheromone induction by a STE7-dependent mechanism. Pheromone also induces the accumulation of STE7 in a hyperphosphorylated form. This modification of STE7 requires the STE11 kinase, which is proposed to act before STE7 during signal transmission. Surprisingly, STE7 hyperphosphorylation also requires a functional FUS3 (or KSS1) kinase. Using in vitro assays for FUS3 phosphorylation, we show that pheromone activates STE7 even in the absence of FUS3 and KSS1. Therefore, STE7 activation must precede modification of FUS3 (and KSS1). These findings suggest that STE7 hyperphosphorylation is a consequence of its activation but not the determining event.
WASTAGE IN HIGHER EDUCATION IN DEVELOPING COUNTRY: A COMPARATIVE STUDY ON SELECTED GRADUATES OF PRIVATE AND PUBLIC UNIVERSITIES OF SYLHET, BANGLADESH
Creators: name: Latif, Abdul
Publisher: name: University of the Thai Chamber of Commerce
Year: 2016
Subjects: Wastage
Higher Education
Unemployment problem
Supply of graduates

description: UTCC International Journal of Business and Economics, 8, 2, 91-104
title: La confusion aiguë chez la personne âgée
title: prévenir et dépister...
titleType: Subtitle
Creators: name: CAVAGNOUD, Séverine
name: LOSSON, Myriam
name: ROSSEL, Brigitte
Publisher: name: Unknown
Year: 0
Subjects: subject: personne âgée
subject: délire
subject: prévention
subject: dépistage
subject: soins infirmiers en gériatrie

description: Introduction : Dans le contexte démographique actuel la problématique de santé des personnes âgées est une préoccupation centrale. La qualité de la prise en soins des ainés devient donc un enjeu de taille pour la profession infirmière. La confusion aiguë est un phénomène fréquent chez la personne âgée hospitalisée. Pourtant elle est largement sous évaluée par les professionnels de la santé alors qu’elle entraine des conséquences néfastes sur la santé et l’avenir de la personne. C’est dans ce contexte que nous avons choisi de nous intéresser au rôle infirmier dans la prévention et le dépistage de la confusion aiguë chez la personne âgée hospitalisée dans un milieu de soins aigus. Méthode : Ce travail est une revue de littérature non exhaustive. Les mots clés choisis sont delirium et acute confusion. Nous avons fait une recherche sur des bases de données, principalement CINHAL, et nous avons identifié des références supplémentaires dans la bibliographie d’articles sélectionnés. Pour la sélection de nos articles scientifiques de référence nous avons utilisé la grille d’analyse du BTEC. Résultats : Nous avons retenu neuf études dont deux sont des revues de littérature. Ces articles couvrent trois axes d’investigation en lien avec notre questionnement : - la reconnaissance de la confusion aiguë par les infirmières - les instruments de dépistage de la confusion aiguë et leur utilisation par les infirmières - les interventions permettant de prévenir l’apparition de la confusion aiguë. Discussion : Il ressort des articles que l’infirmière est la mieux placée pour repérer la confusion aiguë, pourtant son taux de reconnaissance par les infirmières est faible. De nombreuses échelles de dépistage existent et nous avons pu distinguer les plus adaptées à une utilisation infirmière, par exemple la NEECHAM Confusion Scale. Les interventions multidimensionnelles au niveau de la prévention primaire ressortent comme les stratégies les plus efficaces face à la confusion aiguë. Conclusion : La précision de l’évaluation de la confusion aiguë et une meilleure prise en compte de ses facteurs de risque au quotidien sont des défis pour les infirmières afin de garantir des soins de qualité aux personnes âgées hospitalisées.
Physical detection of heteroduplexes during meiotic recombination in the yeast Saccharomyces cerevisiae.
Creators: name: Nag, D K
name: Petes, T D
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: We describe a general physical method for detecting the heteroduplex DNA that is formed as an intermediate in meiotic recombination in the yeast Saccharomyces cerevisiae. We use this method to study the kinetic relationship between the formation of heteroduplex DNA and other meiotic events. We show that strains with the rad50, but not the rad52, mutation are defective in heteroduplex formation. We also demonstrate that, although cruciform structures can be formed in vivo as a consequence of heteroduplex formation between DNA strands that contain different palindromic insertions, small palindromic sequences in homoduplex DNA are rarely extruded into the cruciform conformation.
A very deep Chandra observation of Abell 1795: The Cold Front and Cooling Wake
Creators: name: Ehlert, S.
name: McDonald, M.
name: Miller, E. D.
name: David, L. P.
name: Bautz, M. W.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a new analysis of very deep Chandra observations of the galaxy cluster Abell 1795. Utilizing nearly 750 ks of net ACIS imaging, we are able to resolve the thermodynamic structure of the Intracluster Medium (ICM) on length scales of ~ 1 kpc near the cool core. We find several previously unresolved structures, including a high pressure feature to the north of the BCG that appears to arise from the bulk motion of Abell 1795's cool core. To the south of the cool core, we find low temperature (~ 3 keV), diffuse ICM gas extending for distances of ~ 50 kpc spatially coincident with previously identified filaments of H-alpha emission. Gas at similar temperatures is also detected in adjacent regions without any H-alpha emission. The X-ray gas coincident with the H-alpha filament has been measured to be cooling spectroscopically at a rate of ~ 1 Solar Masses/ yr, consistent with measurements of the star formation rate in this region as inferred from UV observations, suggesting that the star formation in this filament as inferred by its H$α$ and UV emission can trace its origin to the rapid cooling of dense, X-ray emitting gas. The H-alpha filament is not a unique site of cooler ICM, however, as ICM at similar temperatures and even higher metallicities not cospatial with H$α$ emission is observed just to the west of the H-alpha filament, suggesting that it may have been uplifted by Abell 1795's central active galaxy. Further simulations of cool core sloshing and AGN feedback operating in concert with one another will be necessary to understand how such a dynamic cool core region may have originated and why the H-alpha emission is so localized with respect to the cool X-ray gas despite the evidence for a catastrophic cooling flow.
description: 14 Pages, 10 Figures, Resubmitted to ApJ after first referee report, Higher Resolution Figures available upon request
Targetless Extrinsic Calibration of Multiple Small FoV LiDARs and Cameras using Adaptive Voxelization
Creators: name: Liu, Xiyuan
name: Yuan, Chongjian
name: Zhang, Fu
Publisher: name: arXiv
Year: 2021
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Determining the extrinsic parameter between multiple LiDARs and cameras is essential for autonomous robots, especially for solid-state LiDARs, where each LiDAR unit has a very small Field-of-View (FoV), and multiple units are often used collectively. The majority of extrinsic calibration methods are proposed for 360$^\circ$ mechanical spinning LiDARs where the FoV overlap with other LiDAR or camera sensors is assumed. Few research works have been focused on the calibration of small FoV LiDARs and cameras nor on the improvement of the calibration speed. In this work, we consider the problem of extrinsic calibration among small FoV LiDARs and cameras, with the aim to shorten the total calibration time and further improve the calibration precision. We first implement an adaptive voxelization technique in the extraction and matching of LiDAR feature points. Such a process could avoid the redundant creation of $k$-d trees in LiDAR extrinsic calibration and extract LiDAR feature points in a more reliable and fast manner than existing methods. We then formulate the multiple LiDAR extrinsic calibration into a LiDAR Bundle Adjustment (BA) problem. By deriving the cost function up to second-order, the solving time and precision of the non-linear least square problem are further boosted. Our proposed method has been verified on data collected in four targetless scenes and under two types of solid-state LiDARs with a completely different scanning pattern, density, and FoV. The robustness of our work has also been validated under eight initial setups, with each setup containing 100 independent trials. Compared with the state-of-the-art methods, our work has increased the calibration speed 15 times for LiDAR-LiDAR extrinsic calibration and 1.5 times for LiDAR-Camera extrinsic calibration (averaged result from 50 independent trials) while remaining accurate.
description: 12 pages, 15 figures
GREI Collaborative Webinar: Use Cases in Generalist Repositories and Community Feedback
Creators: name: Staller, Amanda
name: Gautier, Julian
name: Lippincott, Sarah
name: Curtin, Lisa
name: Snowden, Traci
name: Olson, Eric
name: Li, Rebecca
name: Holmes, Kristi
Publisher: name: Zenodo
Year: 2023
Subjects: Data Sharing
GREI
Webinar
NIH Data
Open Data
Data repository
Generalist repository

description: Use Cases in Generalist Repositories and Community Feedback | Tuesday, August 1 at 12 pm ET Join Generalist Repository Ecosystem Initiative (GREI) members to learn more about how we center our work on the user experience through a series of use cases from each of the GREI partners. Attendees will be introduced to the four introductory use cases and view demonstrations of the use cases in action. Attendees will also have an opportunity to provide input on the current use cases as well as an interactive feedback session to dig into which use cases you’d like to see next from the GREI program. Finally, the GREI team will provide attendees with a virtual tour of the Zenodo GREI Community where use cases, presentations, reports and other program outputs can be accessed. Speakers: Julian Gautier (Dataverse), Sarah Lippincott (Dryad), Lisa Curtin (Figshare), Traci Snowden (Mendeley), Eric Olson (OSF) Moderated by: Rebecca Li (Vivli), Kristi Holmes (Zenodo) Webinar Recording
Optomechanical Ramsey Interferometry
Creators: name: Qu, Kenan
name: Dong, Chunhua
name: Wang, Hailin
name: Agarwal, G. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We adopt the Ramsey's method of separated oscillatory fields to study coherences of the mechanical system in an optomechanical resonator. The high resolution Ramsey fringes are observed in the emission optical field, when two pulses separated in time are applied. We develop a theory to describe the transient optomechanical behavior underlying the Ramsey fringes. We also perform the experimental demonstration using a silica microresonator. The method is versatile and can be adopted to different types of mechanical resonators, electromechanical resonators.
Missions humanitaires ou l'expérience au service du développement des compétences professionnelles infirmières ?
Creators: name: Sonnay, Madeline
Publisher: name: Unknown
Year: 0
Subjects: subject: aide humanitaire
subject: expérience
subject: développement personnel
subject: compétence professionnelle
subject: réinsertion professionnelle

description: Ce mémoire de fin d’étude a pour but d’analyser de manière inductive, exploratoire et qualitative, comment les ex-coopérants infirmiers valorisent leurs compétences professionnelles développées au travers d’expériences vécues sur le terrain de l’aide humanitaire, lors de leur réinsertion professionnelle, en Suisse. Pour ce faire, j’ai, dans un premier temps, développé un cadre théorique autour des concepts de l’expérience humanitaire, de compétences et du transfert de compétences. J’ai ensuite utilisé les récits de vie et les entretiens semi-dirigés, auprès de trois infirmières ex-coopérantes qui ont vécu une réinsertion professionnelle en Suisse. L’analyse de leurs récits, en lien avec le cadre théorique m’a permis d’identifier six thèmes principaux : le changement, le choc culturel inverse, le soin « ici » et « ailleurs », l’expérience humanitaire, les compétences développées et le transfert de compétences. Les résultats obtenus, m’ont permis de mettre en évidence que le processus de professionnalisation de l’expérience prend du temps et qu’il se construit autour des compétences développées qui doivent faire l’objet d’une relecture. De par son expérience, le coopérant s’est développé tant sur le plan personnel que professionnel. Il a acquis diverses compétences et capacités. Cependant, il a de la difficulté à faire reconnaître le professionnalisme de son expérience. En effet, le travail humanitaire reste méconnu de nos jours. Cette méconnaissance engendre donc des représentations et des malentendus chez les employeurs. C’est tout le problème de l’écart entre la réalité de l’ex-coopérant et celle de son nouveau milieu de travail. De plus, s’il est évident que toutes les compétences acquises sur le terrain de l’aide humanitaire internationale ne peuvent pas être réutilisées ultérieurement, il n’en reste pas moins que les compétences managériales, pédagogiques, linguistiques et humaines sont tout à fait transférable dans les services de soins en Suisse.
Transformation of Saccharomyces cerevisiae with nonhomologous DNA: illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial DNA sequences.
Creators: name: Schiestl, R H
name: Petes, T D
name: Dominska, M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: When the yeast Saccharomyces cerevisiae was transformed with DNA that shares no homology to the genome, three classes of transformants were obtained. In the most common class, the DNA was inserted as the result of a reaction that appears to require base pairing between the target sequence and the terminal few base pairs of the transforming DNA fragment. In the second class, no such homology was detected, and the transforming DNA was integrated next to a CTT or GTT in the target; it is likely that these integration events were mediated by topoisomerase I. The final class involved the in vivo ligation of transforming DNA with nucleus-localized linear fragments of mitochondrial DNA.
Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver.
Creators: name: Sandgren, E P
name: Brinster, R L
name: Luetteke, N C
name: Palmiter, R D
name: Qiu, T H
name: Lee, D C
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: To characterize the effect(s) of transforming growth factor alpha (TGF alpha) during multistage carcinogenesis, we examined tumor development in pancreas and liver of transgenic mice that coexpressed TGF alpha with either viral (simian virus 40 T antigens [TAg]) or cellular (c-myc) oncogenes. In pancreas, TGF alpha itself was not oncogenic, but it nevertheless dramatically accelerated growth of tumors induced by either oncogene alone, thereby reducing the host life span up to 60%. Coexpression of TGF alpha and TAg produced an early synergistic growth response in the entire pancreas together with the more rapid appearance of preneoplastic foci. Coexpression of TGF alpha and c-myc also accelerated tumor growth in situ and produced transplantable acinar cell carcinomas whose rate of growth was TGF alpha dependent. In liver, expression of TGF alpha alone increased the incidence of hepatic cancer in aged mice. However, coexpression of TGF alpha with c-myc or TAg markedly reduced tumor latency and accelerated tumor growth. Significantly, expression of the TGF alpha and myc transgenes in hepatic tumors was induced up to 20-fold relative to expression in surrounding nonneoplastic liver, suggesting that high-level overexpression of these proteins acts as a major stimulus for tumor development. Finally, in both pancreas and liver, combined expression of TGF alpha and c-myc produced tumors with a more malignant (less differentiated) appearance than did expression of c-myc alone, consistent with an influence of TGF alpha upon the morphological character of c-myc-induced tumor progression. These findings demonstrate the importance of TGF alpha expression during multistage carcinogenesis in vivo and point to a major role for this growth factor as a potent stimulator of tumor growth.
LoGG3D-Net: Locally Guided Global Descriptor Learning for 3D Place Recognition
Creators: name: Vidanapathirana, Kavisha
name: Ramezani, Milad
name: Moghadam, Peyman
name: Sridharan, Sridha
name: Fookes, Clinton
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Retrieval-based place recognition is an efficient and effective solution for re-localization within a pre-built map, or global data association for Simultaneous Localization and Mapping (SLAM). The accuracy of such an approach is heavily dependent on the quality of the extracted scene-level representation. While end-to-end solutions - which learn a global descriptor from input point clouds - have demonstrated promising results, such approaches are limited in their ability to enforce desirable properties at the local feature level. In this paper, we introduce a local consistency loss to guide the network towards learning local features which are consistent across revisits, hence leading to more repeatable global descriptors resulting in an overall improvement in 3D place recognition performance. We formulate our approach in an end-to-end trainable architecture called LoGG3D-Net. Experiments on two large-scale public benchmarks (KITTI and MulRan) show that our method achieves mean $F1_{max}$ scores of $0.939$ and $0.968$ on KITTI and MulRan respectively, achieving state-of-the-art performance while operating in near real-time. The open-source implementation is available at: https://github.com/csiro-robotics/LoGG3D-Net.
description: Accepted - ICRA 2022
title: Anesthésie et rôle propre infirmier
title: intérêts et enjeux du dialogue péri-opératoire dans le cadre de la relation de soins
titleType: Subtitle
Creators: name: Hatet, Olivier
name: Moillen, Christian
Publisher: name: Unknown
Year: 0
Subjects: subject: soins préopératoires
subject: anesthésie
subject: relation soignant-soigné
subject: rôle infirmier

description: Le but est d'analyser la pertinence du modèle organisationnel baptisé dialogue péri-opératoire et sa propension à valoriser le rôle propre infirmier dans un contexte d’anesthésiologie. Contexte : nous souhaitions à l’origine centrer nos recherches sur la question du rôle propre infirmier à l’accueil du bloc opératoire. Pourtant, après avoir parcouru une partie de la littérature scientifique y relative, nous avons découvert un outil innovant en termes de prise en charge de patients contraints de recourir à une intervention chirurgicale élective : le dialogue péri-opératoire. En synthèse, il est défini comme les rencontres pré, per et postopératoires entre une infirmière et un patient en rapport avec l’annonce et la programmation d’une opération. Méthode : revue de littérature élaborée à partir des bases de données CINAHL, MEDLINE et BDSP qui sélectionne, synthétise et compare les résultats de neuf recherches en soins infirmiers propres au dialogue péri-opératoire. Son objectif est d’analyser les retombées cliniques concrètes ou potentielles de ce modèle sur les patients devant subir une intervention chirurgicale programmée et sur l’organisation du travail d’infirmières diplômées affectées au bloc opératoire. Par bloc opératoire, nous entendons tant les infrastructures d’accueil, que les salles d’opérations ou de réveil. Résultats : le dialogue péri-opératoire nous a interpellés dans la mesure où il répond à l’ensemble des critères de qualité propres au suivi infirmier d’un patient avant, pendant et après son intervention. En ce sens, les résultats des recherches que nous avons étudiés démontrent, d’une part, que ce modèle permet aux infirmières de développer une approche holistique et individualisée des situations cliniques qu’elles rencontrent et favorise la continuité des soins. D’autre part, qu’il améliore la visibilité de la fonction infirmière auprès des patients et des décideurs. Conclusion : nous pensons que la reconnaissance et la mise en oeuvre de ce modèle organisationnel novateur implique de multiples enjeux tant pour les soignants : continuité des soins, responsabilisation et implication des infirmières à l’égard des malades ; que pour les patients : prise en charge individualisée, respect des besoins spécifiques, accompagnement personnalisé, etc. En outre, il nous paraît susceptible d’être vecteur d’amélioration de la qualité et de la visibilité des soins infirmiers dans les services d’anesthésiologie et de chirurgie.
Collisionless accretion onto black holes: dynamics and flares
Creators: name: Galishnikova, Alisa
name: Philippov, Alexander
name: Quataert, Eliot
name: Bacchini, Fabio
name: Parfrey, Kyle
name: Ripperda, Bart
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We study the accretion of collisionless plasma onto a rotating black hole from first principles using axisymmetric general-relativistic particle-in-cell simulations. We carry out a side-by-side comparison of these results to analogous general-relativistic magnetohydrodynamic simulations. Although there are many similarities in the overall flow dynamics, three key differences between the kinetic and fluid simulations are identified. Magnetic reconnection is more efficient, and rapidly accelerates a nonthermal particle population, in our kinetic approach. In addition, the plasma in the kinetic simulations develops significant departures from thermal equilibrium, including pressure anisotropy that excites kinetic-scale instabilities, and a large field-aligned heat flux near the horizon that approaches the free-streaming value. We discuss the implications of our results for modeling event-horizon scale observations of Sgr A* and M87 by GRAVITY and the Event Horizon Telescope.
description: 10 pages, 8 figures, submitted
Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation.
Creators: name: Finco, T S
name: Nantermet, P V
name: Baldwin, A S
name: Beg, A A
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Nuclear factor kappa B (NF-kappa B) is a critical regulator of several genes which are involved in immune and inflammation responses. NF-kappa B, consisting of a 50-kDa protein (p50) and a 65-kDa protein (p65), is bound to a cytoplasmic retention protein called I kappa B. Stimulation of cells with a variety of inducers, including cytokines such as tumor necrosis factor and interleukin-1, leads to the activation and the translocation of p50/65 NF-kappa B into the nucleus. However, the in vivo mechanism of the activation process remains unknown. Here, we provide the first evidence that the in vivo mechanism of NF-kappa B activation is through the phosphorylation and subsequent loss of its inhibitor, I kappa B alpha. We also show that both I kappa B alpha loss and NF-kappa B activation are inhibited in the presence of antioxidants, demonstrating that the loss of I kappa B alpha is a prerequisite for NF-kappa B activation. Finally, we demonstrate that I kappa B alpha is rapidly resynthesized after loss, indicating that an autoregulatory mechanism is involved in the regulation of NF-kappa B function. We propose a mechanism for the activation of NF-kappa B through the modification and loss of I kappa B alpha, thereby establishing its role as a mediator of NF-kappa B activation.
A quaternionic fractional Borel-Pompeiu type formula
Creators: name: González-Cervantes, José Oscar
name: Bory-Reyes, Juan
Publisher: name: arXiv
Year: 2021
Subjects: subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: 30G30, 30G35, 32A36, 35A08, 35R11, 45P05

description: Quaternionic analysis relies heavily on results on functions defined on domains in $\mathbb R^4$ (or $\mathbb R^3$) with values in $\mathbb H$. This theory is centered around the concept of $ψ-$hyperholomorphic functions i.e., null-solutions of the $ψ-$Fueter operator related to a so-called structural set $ψ$ of $\mathbb H^4$. Fractional calculus, involving derivatives-integrals of arbitrary real or complex order, is the natural generalization of the classical calculus, which in the latter years became a well-suited tool by many researchers working in several branches of science and engineering. In theoretical setting, associated with a fractional $ψ-$Fueter operator that depends on an additional vector of complex parameters with fractional real parts, this paper establishes a fractional analogue of Borel-Pompeiu formula as a first step to develop a fractional $ψ-$hyperholomorphic function theory and the related operator calculus.
Trajectory Distribution Control for Model Predictive Path Integral Control using Covariance Steering
Creators: name: Yin, Ji
name: Zhang, Zhiyuan
name: Theodorou, Evangelos
name: Tsiotras, Panagiotis
Publisher: name: arXiv
Year: 2021
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: This paper presents a novel control approach for autonomous systems operating under uncertainty. We combine Model Predictive Path Integral (MPPI) control with Covariance Steering (CS) theory to obtain a robust controller for general nonlinear systems. The proposed Covariance-Controlled Model Predictive Path Integral (CC-MPPI) controller addresses the performance degradation observed in some MPPI implementations owing to unexpected disturbances and uncertainties. Namely, in cases where the environment changes too fast or the simulated dynamics during the MPPI rollouts do not capture the noise and uncertainty in the actual dynamics, the baseline MPPI implementation may lead to divergence. The proposed CC-MPPI controller avoids divergence by controlling the dispersion of the rollout trajectories at the end of the prediction horizon. Furthermore, the CC-MPPI has adjustable trajectory sampling distributions that can be changed according to the environment to achieve efficient sampling. Numerical examples using a ground vehicle navigating in challenging environments demonstrate the proposed approach.
description: "Previously titled "Improving Model Predictive Path Integral Using Covariance Steering", this paper is one of the Outstanding Planning Paper Award finalists in ICRA 2022. For associated video, see https://www.youtube.com/watch?v=cZq4tnBTIqc ."
Resonance capture at arbitrary inclination
Creators: name: Namouni, Fathi
name: Morais, Maria Helena Moreira
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Resonance capture is studied numerically in the three-body problem for arbitrary inclinations. Massless particles are set to drift from outside the 1:5 resonance with a Jupiter-mass planet thereby encountering the web of the planet's diverse mean motion resonances. Randomly constructed samples explore parameter space for inclinations from 0 to 180 deg with 5deg increments totalling nearly 6x10^5 numerical simulations. Thirty resonances internal and external to the planet's location are monitored. We find that retrograde resonances are unexpectedly more efficient at capture than prograde resonances and that resonance order is not necessarily a good indicator of capture efficiency at arbitrary inclination. Capture probability drops significantly at moderate sample eccentricity for initial inclinations in the range [10deg,110deg]. Orbit inversion is possible for initially circular orbits with inclinations in the range [60deg,130deg]. Capture in the 1:1 coorbital resonance occurs with great likelihood at large retrograde inclinations. The planet's orbital eccentricity, if larger than 0.1, reduces the capture probabilities through the action of the eccentric Kozai-Lidov mechanism. A capture asymmetry appears between inner and outer resonances as prograde orbits are preferentially trapped in inner resonances. The relative capture efficiency of retrograde resonance suggests that the dynamical lifetimes of Damocloids and Centaurs on retrograde orbits must be significantly larger than those on prograde orbits implying that the recently identified asteroids in retrograde resonance, 2006 BZ8, 2008 SO218, 2009 QY6 and 1999 LE31(Morais and Namouni, 2013, MNRAS 436, L30) may be among the oldest small bodies that wander between the outer giant planets.
description: 16 pages. Accepted for publication in MNRAS
Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation.
Creators: name: D'Eustachio, P
name: Drivas, G
name: Graham, S M
name: Der, C J
name: Rush, M G
name: Cox, A D
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: Although the human Ras proteins are members of a large superfamily of Ras-related proteins, to date, only the proteins encoded by the three mammalian ras genes have been found to possess oncogenic potential. Among the known Ras-related proteins, TC21/R-Ras2 exhibits the most significant amino acid identity (55%) to Ras proteins. We have generated mutant forms of TC21 that possess amino acid substitutions analogous to those that activate Ras oncogenic potential [designated TC21(22V) and TC21(71L)] and compared the biological properties of TC21 with those of Ras proteins in NIH 3T3 and Rat-1 transformation assays. Whereas wild-type TC21 did not show any transforming potential in vitro, both TC21(22V) and TC21(71L) displayed surprisingly potent transforming activities that were comparable to the strong transforming activity of oncogenic Ras proteins. Like Ras-transformed cells, NIH 3T3 cells expressing mutant TC21 proteins formed foci of morphologically transformed cells in monolayer cultures, proliferated in low serum, formed colonies in soft agar, and developed progressive tumors in nude mice. Thus, TC21 is the first Ras-related protein to exhibit potent transforming activity equivalent to that of Ras. Furthermore, mutant TC21 proteins also stimulated constitutive activation of mitogen-activated protein kinases as well as transcriptional activation from Ras-responsive promoter elements (Ets/AP-1 and NF-kappa B). We conclude that aberrant TC21 function may trigger cellular transformation via a signal transduction pathway similar to that of oncogenic Ras and suggest that deregulated TC21 activity may contribute significantly to human oncogenesis.
Non-Abelian effects in dissipative photonic topological lattices
Creators: name: Parto, Midya
name: Leefmans, Christian
name: Williams, James
name: Nori, Franco
name: Marandi, Alireza
Publisher: name: arXiv
Year: 2022
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Topology is central to phenomena that arise in a variety of fields, ranging from quantum field theory to quantum information science to condensed matter physics. Recently, the study of topology has been extended to open systems, leading to a plethora of intriguing effects such as topological lasing, exceptional surfaces, as well as the non-Hermitian bulk-boundary correspondence. Here, we show that resonator networks with dissipative couplings can be governed by matrix-valued modified Wilson lines, leading to non-Abelian effects. This is in contrast to conservative Hamiltonians exhibiting non-degenerate energy levels, where the geometric properties of the Bloch eigenstates are typically characterized by scalar Berry phases. We experimentally measure geometric phases and demonstrate non-Abelian effects in a dissipatively-coupled network of time-multiplexed photonic resonators. Our results point to new ways in which the combined effect of topology and engineered dissipation can lead to non-Abelian topological phenomena.
title: Concevoir l'accompagnement des parents dont l'enfant est atteint d'un cancer
title: que vivent-ils, quels sont leurs besoins et comment l'infirmière peut-elle y répondre ?
titleType: Subtitle
Creators: name: Bonjour, Noémie
name: Reis, Cátea
name: Riess, Félicia
Publisher: name: Unknown
Year: 0
Subjects: subject: enfant
subject: cancer
subject: relation soignant-famille
subject: accompagnement
subject: rôle infirmier

description: « Concevoir l'accompagnement des parents dont l'enfant est atteint d'un cancer. Que vivent-ils, quels sont leurs besoins et comment l'infirmière peut-elle y répondre? » Ce sont les questions auxquelles nous cherchons à répondre à travers cette revue de littérature. La portée du cancer d’un enfant dans la société actuelle et le poids émotionnel qu'il engendre au sein des équipes soignantes ainsi que dans les familles, donnent à ce sujet tout son intérêt. Identifier les caractéristiques de cette expérience et les besoins qui en découlent, nous permet, en tant que futures infirmières, de cibler nos interventions afin d'être au plus près des parents en leur apportant le soutien nécessaire. Les sept articles sur lesquels nous nous sommes basées pour construire ce travail sont pour la plupart des recherches scientifiques menées par des infirmières. Cinq articles sont qualitatifs, un est quantitatif et le dernier est une revue de littérature. Nos recherches ont principalement été effectuées sur les bases de données Cinahl, Medline et Rero. Certains articles mettent l'accent sur ce que vivent les familles et comment cela affecte la dynamique familiale, d'autres se sont plus centrés sur les besoins des parents et donnent des recommandations et/ou des perspectives afin de poursuivre les recherches sur le sujet. Les résultats de ces différentes études sont complémentaires, ce qui nous a permis d'identifier les principaux besoins pour ainsi construire et développer notre pratique professionnelle.
Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras.
Creators: name: Solski, P A
name: Burridge, K
name: Der, C J
name: Khosravi-Far, R
name: Eva, A
name: Chrzanowska-Wodnicka, M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: Vav and Dbl are members of a novel class of oncogene proteins that share significant sequence identity in a approximately 250-amino-acid domain, designated the Dbl homology domain. Although Dbl functions as a guanine nucleotide exchange factor (GEF) and activator of Rho family proteins, recent evidence has demonstrated that Vav functions as a GEF for Ras proteins. Thus, transformation by Vav and Dbl may be a consequence of constitutive activation of Ras and Rho proteins, respectively. To address this possibility, we have compared the transforming activities of Vav and Dbl with that of the Ras GEF, GRF/CDC25. As expected, GRF-transformed cells exhibited the same reduction in actin stress fibers and focal adhesions as Ras-transformed cells. In contrast, Vav- and Dbl-transformed cells showed the same well-developed stress fibers and focal adhesions observed in normal or RhoA(63L)-transformed NIH 3T3 cells. Furthermore, neither Vav- or Dbl-transformed cells exhibited the elevated levels of Ras-GTP (60%) observed with GRF-transformed cells. Finally, GRF, but not Vav or Dbl, induced transcriptional activation from Ras-responsive DNA elements (ets/AP-1, fos promoter, and kappa B). However, like Ras- and GRF-transformed cells, both Vav- and Dbl-transformed cells exhibited constitutively activated mitogen-activated protein kinases (MAPKs) (primarily p42MAPK/ERK2). Since kinase-deficient forms of p42MAPK/ERK2 and p44MAPK/ERK1 inhibited Dbl transformation, MAPK activation may be an important component of its transforming activity. Taken together, our observations indicate that Vav and Dbl transformation is not a consequence of Ras activation and instead may involve the constitutive activation of MAPKs.
Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy.
Creators: name: Detloff, P J
name: John, S W
name: Lewis, J
name: Shehee, W R
name: Maeda, N
name: Langenbach, R
name: Smithies, O
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: We describe a two-step strategy to alter any mouse locus repeatedly and efficiently by direct positive selection. Using conventional targeting for the first step, a functional neo gene and a nonfunctional HPRT minigene (the "socket") are introduced into the genome of HPRT- embryonic stem (ES) cells close to the chosen locus, in this case the beta-globin locus. For the second step, a targeting construct (the "plug") that recombines homologously with the integrated socket and supplies the remaining portion of the HPRT minigene is used; this homologous recombination generates a functional HPRT gene and makes the ES cells hypoxanthine-aminopterin-thymidine resistant. At the same time, the plug provides DNA sequences that recombine homologously with sequences in the target locus and modifies them in the desired manner; the plug is designed so that correctly targeted cells also lose the neo gene and become G418 sensitive. We have used two different plugs to make alterations in the mouse beta-globin locus starting with the same socket-containing ES cell line. One plug deleted 20 kb of DNA containing the two adult beta-globin genes. The other replaced the same region with the human beta-globin gene containing the mutation responsible for sickle cell anemia.
Quel accompagnement pour l'enfant africain hospitalisé en Suisse ?
Creators: name: Haab, Angelica
name: Junod, Eve
Publisher: name: Unknown
Year: 0
Subjects: subject: enfant
subject: migrant
subject: hospitalisation
subject: accompagnement
subject: relation soignant-soigné

description: La présence des enfants d’origine étrangère transférés par le biais d’associations humanitaires est une réalité dans nos services de soin. Ces enfants sont d’autant plus vulnérables qu’ils sont seuls, et de culture différente de la nôtre. De ce fait, nous pouvons difficilement nous représenter ce qu’ils vivent, et ce dont ils ont besoin. Ce manque de connaissances peut affecter l’accompagnement infirmier et le jugement clinique. La qualité de la prise en soin de cette population devient donc un enjeu de taille pour la profession infirmière. Notre question de recherche est : Comment prendre en soin les enfants d’origine africaine hospitalisés temporairement en Suisse par le biais d’associations humanitaires ? Ce travail est une revue de littérature non exhaustive. Nous avons fait une recherche sur des bases de données, principalement Cinahl et Medline. Des références supplémentaires ont été identifiées dans la bibliographie d’articles sélectionnés. Pour l’analyse des articles scientifiques de référence nous avons utilisé le modèle de grille d’analyse de Loiselle & Profetto-McGratt (2007.) Nous avons retenu huit études dont une est une revue de littérature. Si aucune ne se situe au centre du sujet, elles se complètent et couvrent le champ de la problématique. Deux explorent la perspective des enfants quant à leur hospitalisation, trois concernent la thématique des enfants non-accompagnés, et trois abordent les compétences culturelles. Les articles mettent en évidence la place prépondérante des infirmières pour évaluer les besoins de ces enfants, et pallier à leurs manques. Pourtant, celles-ci ne se sentent pas adéquates pour accomplir ce rôle car il leur manque des compétences et des moyens, notamment au niveau culturel. Des interventions multidimensionnelles, autant au niveau des infirmières qu'au niveau des enfants, ressortent comme les stratégies les plus efficaces pour rendre le séjour des enfants le moins traumatisant possible. La revue de littérature a permis de proposer des pistes d’intervention pour améliorer la prise en soin des enfants transférés par l'intermédiaire de fondations humanitaires. Cependant, il manque des recherches concernant la prise en soin de cette population particulière. Des études exploratrices ou descriptives permettraient une meilleure compréhension du vécu des enfants, et de ce fait, des interventions infirmières adéquates.
Efficient quantum state tomography with convolutional neural networks
Creators: name: Schmale, Tobias
name: Reh, Moritz
name: Gärttner, Martin
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Modern day quantum simulators can prepare a wide variety of quantum states but the accurate estimation of observables from tomographic measurement data often poses a challenge. We tackle this problem by developing a quantum state tomography scheme which relies on approximating the probability distribution over the outcomes of an informationally complete measurement in a variational manifold represented by a convolutional neural network. We show an excellent representability of prototypical ground- and steady states with this ansatz using a number of variational parameters that scales polynomially in system size. This compressed representation allows us to reconstruct states with high classical fidelities outperforming standard methods such as maximum likelihood estimation. Furthermore, it achieves a reduction of the estimation error of observables by up to an order of magnitude compared to their direct estimation from experimental data.
description: 11 pages, 6 figures