cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Distribution and lateral mobility of DC-SIGN on immature dendritic cells-implications for pathogen uptake
Creators: name: Thompson, Nancy L.
name: Neumann, Aaron K.
name: Jacobson, Ken
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The receptor C-type lectin DC-SIGN (CD209) is expressed by immature dendritic cells, functioning as an antigen capture receptor and cell adhesion molecule. Various microbes, including HIV-1, can exploit binding to DC-SIGN to gain entry to dendritic cells. DC-SIGN forms discrete nanoscale clusters on immature dendritic cells that are thought to be important for viral binding. We confirmed that these DC-SIGN clusters also exist both in live dendritic cells and in cell lines that ectopically express DC-SIGN. Moreover, DC-SIGN has an unusual polarized lateral distribution in the plasma membrane of dendritic cells and other cells: the receptor is preferentially localized to the leading edge of the dendritic cell lamellipod and largely excluded from the ventral plasma membrane. Colocalization of DC-SIGN clusters with endocytic activity demonstrated that surface DC-SIGN clusters are enriched near the leading edge, whereas endocytosis of these clusters occurred preferentially at lamellar sites posterior to the leading edge. Therefore, we predicted that DC-SIGN clusters move from the leading edge to zones of internalization. Two modes of lateral mobility were evident from the trajectories of DC-SIGN clusters at the leading edge, directed and non-directed mobility. Clusters with directed mobility moved in a highly linear fashion from the leading edge to rearward locations in the lamella at remarkably high velocity (1420+/-260 nm/second). Based on these data, we propose that DC-SIGN clusters move from the leading edge--where the dendritic cell is likely to encounter pathogens in tissue--to a medial lamellar site where clusters enter the cell via endocytosis. Immature dendritic cells may acquire and internalize HIV and other pathogens by this process.
Table S9 from Comparative genomic analysis of the ‘psuedofungus’ Hyphochytrium catenoides
Creators: name: Leonard, Guy
name: Labarre, Aurélie
name: Milner, David S.
name: Monier, Adam
name: Soanes, Darren
name: Wideman, Jeremy G.
name: Maguire, Finlay
name: Stevens, Sam
name: Sain, Divya
name: Grau-Bove, Xavier
name: Arnau Sebe-Pedros
name: Stajich, Jason E.
name: Paszkiewicz, Konrad
name: Brown, Matthew W.
name: Hall, Neil
name: Wickstead, Bill
name: Richards, Thomas A.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences

description: List of genomes used in contamination comparisons
Additional file 10 of Oral health-related quality of life in 4–16-year-olds with and without juvenile idiopathic arthritis
Creators: name: Gil, Elisabeth G.
name: Skeie, Marit S.
name: Halbig, Josefine
name: Jönsson, Birgitta
name: Lie, Stein Atle
name: Rygg, Marite
name: Fischer, Johannes
name: Rosén, Annika
name: Bletsa, Athanasia
name: Luukko, Keijo
name: Shi, Xie-Qi
name: Frid, Paula
name: Cetrelli, Lena
name: Tylleskär, Karin
name: Rosendahl, Karen
name: Åstrøm, Anne N.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 10. Table S1. Disease-specific features and dental caries in relation to the outcome variable Early Childhood Oral Health Impact Scale (ECOHIS) total score and Child Oral Impacts on Daily Performance (Child-OIDP) simple count (SC) score. Unadjusted and adjusted negative binominal regressions.
The density of small tight junction pores varies among cell types and is increased by expression of claudin-2
Creators: name: van Itallie, Christina M.
name: Proctor, William
name: Holmes, Jennifer
name: Bridges, Arlene
name: Gookin, Jody L.
name: Coccaro, Maria R.
name: Colegio, Oscar R.
name: Anderson, James M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Epithelial tight junctions contain size- and charge-selective pores that control the paracellular movement of charged and noncharged solutes. Claudins influence the charge selectivity and electrical resistance of junctions, but there is no direct evidence describing pore composition or whether pore size or density differs among cell types. To characterize paracellular pores independent of influences from charge selectivity, we profiled the ;apparent permeabilities' (P(app)) of a continuous series of noncharged polyethylene glycols (PEGs) across monolayers of five different epithelial cell lines and porcine ileum. We also characterized P(app) of high and low electrical resistance MDCK cell monolayers expressing heterologous claudins. P(app) profiling confirms that the paracellular barrier to noncharged solutes can be modeled as two distinct pathways: high-capacity small pores and a size-independent pathway allowing flux of larger solutes. All cell lines and ileum share a pore aperture of radius 4 A. Using P(app) of a PEG of radius 3.5 A to report the relative pore number provides the novel insight that pore density along the junction varies among cell types and is not necessarily related to electrical resistance. Expression of claudin-2 results in a selective increase in pore number but not size and has no effect on the permeability of PEGs that are larger than the pores; however, neither knockdown of claudin-2 nor overexpression of several other claudins altered either the number of small pores or their size. We speculate that permeability of all small solutes is proportional to pore number but that small electrolytes are subject to further selectivity by the profile of claudins expressed, explaining the dissociation between the P(app) for noncharged solutes and electrical resistance. Although claudins are likely to be components of the small pores, other factors might regulate pore number.
The Milnor number of plane irreducible singularities in positive characteristic
Creators: name: Barroso, Evelia R. García
name: Płoski, Arkadiusz
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: Primary 32S05, Secondary 14H20

description: \noindent Let $μ(f)$ resp. $c(f)$ be the Milnor number resp. the degree of the conductor of an irreducible power series $f\in \bK[[x,y]]$, where $\bK$ is an algebraically closed field of characteristic $p\geq 0$. It is well-known that $μ(f)\geq c(f)$. We give necessary and sufficient conditions for the equality $μ(f)=c(f)$ in terms of the semigroup associated with $f$, provided that $p>\ord f$.
description: 8 pages
Additional file 1 of Oral health-related quality of life in 4–16-year-olds with and without juvenile idiopathic arthritis
Creators: name: Gil, Elisabeth G.
name: Skeie, Marit S.
name: Halbig, Josefine
name: Jönsson, Birgitta
name: Lie, Stein Atle
name: Rygg, Marite
name: Fischer, Johannes
name: Rosén, Annika
name: Bletsa, Athanasia
name: Luukko, Keijo
name: Shi, Xie-Qi
name: Frid, Paula
name: Cetrelli, Lena
name: Tylleskär, Karin
name: Rosendahl, Karen
name: Åstrøm, Anne N.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1. Sample size calculation.
The giant acoustic atom -- a single quantum system with a deterministic time delay
Creators: name: Guo, Lingzhen
name: Grimsmo, Arne
name: Kockum, Anton Frisk
name: Pletyukhov, Mikhail
name: Johansson, Göran
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the quantum dynamics of a single transmon qubit coupled to surface acoustic waves (SAWs) via two distant connection points. Since the acoustic speed is five orders of magnitude slower than the speed of light, the travelling time between the two connection points needs to be taken into account. Therefore, we treat the transmon qubit as a giant atom with a deterministic time delay. We find that the spontaneous emission of the system, formed by the giant atom and the SAWs between its connection points, initially decays polynomially in the form of pulses instead of a continuous exponential decay behaviour, as would be the case for a small atom. We obtain exact analytical results for the scattering properties of the giant atom up to two-phonon processes by using a diagrammatic approach. We find that two peaks appear in the inelastic (incoherent) power spectrum of the giant atom, a phenomenon which does not exist for a small atom. The time delay also gives rise to novel features in the reflectance, transmittance, and second-order correlation functions of the system. Furthermore, we find the short-time dynamics of the giant atom for arbitrary drive strength by a numerically exact method for open quantum systems with a finite-time-delay feedback loop.
description: To be published on Physical Review A
The connection between starspots and superflares: a case study of two stars
Creators: name: Araújo, Alexandre
name: Valio, Adriana
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: How do the characteristics of starspots influence the triggering of stellar flares? Here we investigate the activity of two K-type stars, similar in every way from mass to rotation periods and planetary systems. Both stars exhibit about a hundred spots, however, Kepler-411 produced 65 superflares, while Kepler-210 presented none. The spots of both stars were characterized using the planetary transit mapping technique, which yields the intensity, temperature, and radius of starspots. The average radius was $(17\pm7) \times 10^3$ km and $(58 \pm 23) \times 10^3$ km, while the intensity ratio with respect to the photosphere was $(0.35\pm0.24)$ $I_{c}$ and $(0.64\pm0.15)$ $I_{c}$, and the temperature was $(3800 \pm 700)$ K and $(4180 \pm 240)$ K for spots of Kepler-411 and Kepler-210, respectively. Therefore, spots on the star with no superflares, Kepler-210, are mostly larger, less dark, and warmer than those on the flaring star, Kepler-411. This may indicate magnetic fields with smaller magnitude and complexity of the spots on Kepler-210 when compared to those on Kepler-411. Thus, starspot area appears not to be the main culprit of superflares triggering. Perhaps the magnetic complexity of active regions is more important.
description: 5 pages,4 Figures
Figure S7 from Comparative genomic analysis of the ‘psuedofungus’ Hyphochytrium catenoides.
Creators: name: Leonard, Guy
name: Labarre, Aurélie
name: Milner, David S.
name: Monier, Adam
name: Soanes, Darren
name: Wideman, Jeremy G.
name: Maguire, Finlay
name: Stevens, Sam
name: Sain, Divya
name: Grau-Bove, Xavier
name: Arnau Sebe-Pedros
name: Stajich, Jason E.
name: Paszkiewicz, Konrad
name: Brown, Matthew W.
name: Hall, Neil
name: Wickstead, Bill
name: Richards, Thomas A.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences

description: Eukaryotic microbes have three primary mechanisms for obtaining nutrients and energy: phagotrophy, photosynthesis and osmotrophy. Traits associated with the latter two functions arose independently multiple times in the eukaryotes. Fungi successfully coupled osmotrophy with filamentous growth, similar traits are also manifested in the Pseudofungi (oomycetes and hyphochytriomycetes). Both the Fungi and the Pseudofungi encompass a diversity of plant and animal parasites. Genome-sequencing efforts have focused on host-associated microbes (mutualistic symbionts or parasites), providing limited comparisons with free-living relatives. Here we report the first draft genome sequence of a hyphochytriomycete ‘pseudofungus’; Hyphochytrium catenoides. Using phylogenomic approaches, we identify genes of recent viral ancestry, with related viral derived genes also present on the genomes of oomycetes, suggesting a complex history of viral coevolution and integration across the Pseudofungi. H. catenoides has a complex life cycle involving diverse filamentous structures and a flagellated zoospore with a single anterior-tinselate flagellum. We use genome comparisons, drug sensitivity analysis and high-throughput culture arrays to investigate the ancestry of oomycete/pseudofungal characteristics and metabolic traits, demonstrating that many of the genetic features associated with pathogenic traits evolved specifically within the oomycete radiation. Comparative genomics also identified differences in the repertoire of genes associated with filamentous growth between the Fungi and the Pseudofungi, including differences in vesicle trafficking systems, cell-wall synthesis pathways and motor protein repertoire, demonstrating that unique cellular systems underpinned the convergent evolution of filamentous osmotrophic growth in these two eukaryotic groups.
NMR dynamics of quantum discord for spin-carrying gas molecules in a closed nanopore
Creators: name: Yurischev, M. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A local orthogonal transformation that transforms any centrosymmetric (CS) matrix of fourth order to the X form is found. A picewise-analytic-numerical formula Q=min{Q_π/2,Q_θ,Q_0}, where Q_π/2 and Q_0 are analytical expressions and the branch Q_θ is found by numerical searching the optimal measurement angle θ\in(0,π/2), is proposed to calculate the quantum discord Q of general X state. The developed approaches are applied to a quantitative description of recently predicted flickerings (periodic birth and death) of the quantum-information pair correlation between nuclear 1/2 spin of atoms or molecules of a gas (for examples Xe^129) in a finite asymmetric volume in the presence of a strong magnetic field.
description: 10 pages, 7 figures
DOWNLOAD [PDF] {EPUB} The Score That Matters: Growing Excellence in Yourself and Those You Lead by Ryan Hawk, Brook Cupps
Creators: name: Winter
Publisher: name: Zenodo
Year: 2024

description: The Score That Matters: Growing Excellence in Yourself and Those You Lead by Ryan Hawk, Brook Cupps

 

 

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The Score That Matters: Growing Excellence in Yourself and Those You Lead

Ryan Hawk, Brook Cupps

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ISBN: 9781637745236

Publisher: BenBella Books, Inc.

 

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The Score That Matters (Growing Excellence in Yourself Prefer to work with a human being when you order The Score That Matters (Growing Excellence in Yourself and Those You Lead) books in bulk? Our Book Specialists  The Score That Matters: Growing Excellence in Yourself and Those An indispensable guide to redefining success and sustaining excellence based on who you are and what you value from the authors of The Pursuit of Excellence  The Learning Leader Show: Keynote Leadership Speaker Dec 13, 2023 — Building Organizational Leadership Capacity by DR Kolzow · Cited by 196 — Growing Excellence in Yourself and Those You Lead 書名:The Score That Matters: Growing Excellence in Yourself and Those You Lead,語言:英文,ISBN:9781501269110,作者:Hawk, Ryan,Cupps, Brook,  The Score That Matters | Ryan Hawk Book | Pre-Order Now Buy The Score That Matters by Ryan Hawk for $60.00 at Mighty Ape NZ. Pre The Score That Matters. Growing Excellence in Yourself and Those You Lead. 1 2 How to Answer the 64 Toughest Interview Questions As for your future, you believe that if you perform each job at hand with excellence, future opportunities will take care of themselves. Example: "I am  The Score That Matters eBook by Ryan Hawk - EPUB Book Read "The Score That Matters Growing Excellence in Yourself and Those You Lead" by Ryan Hawk available from Rakuten Kobo. Redefine success based on who you  Growing Excellence in Yourself and Those You Lead The Score That Matters: Growing Excellence in Yourself and Those You Lead. Schrijf een review. Delen. Afbeeldingen. The Score That Matters: Growing  The Score That Matters: Growing Excellence in Yourself Redefine success based on who you are and what you value with this indispensable guide from the authors of The Pursuit of Excellence and. The Score That Matters | Ryan Hawk; Brook Cupps The Score That Matters. Growing Excellence in Yourself and Those You Lead. by Ryan Hawk; Brook Cupps. This title was previously available on NetGalley and is
Coronin 2A regulates a subset of focal-adhesion-turnover events through the cofilin pathway
Creators: name: Bear, James E.
name: Aloor, Heather L.
name: Marshall, Thomas W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Coronins are conserved F-actin-binding proteins that are important for motility and actin dynamics. Unlike type I coronins, coronin 2A localizes to stress fibers and some focal adhesions, and is excluded from the leading edge. Depletion of coronin 2A in MTLn3 cells decreases cell motility and turnover of focal adhesions. Surprisingly, none of the pathways known to regulate focal-adhesion turnover are affected by depletion of coronin 2A. Depletion of coronin 2A does, however, increase phospho-cofilin, suggesting that misregulation of cofilin might affect adhesion dynamics. Slingshot-1L, a cofilin-activating phosphatase, localizes to focal adhesions and interacts with coronin 2A. Depletion of coronin 2A reduces cofilin activity at focal adhesions, as measured by barbed-end density and actin FRAP. In both fixed cells and live cells, cofilin localizes to the proximal end of some focal adhesions. Although expression of wild-type cofilin in coronin-2A-depleted cells has no major effect on focal-adhesion dynamics, expression of an active mutant of cofilin bypasses the defects in cell motility and focal-adhesion disassembly. These results implicate both coronin 2A and cofilin as factors that can regulate a subset of focal-adhesion-turnover events.
[PDF EPUB] Download Gloomspite by Andy Clark Full Book
Creators: name: Holiday
Publisher: name: Zenodo
Year: 2024

description: Gloomspite by Andy Clark

 

 

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Gloomspite

Andy Clark

Page: 368

Format: pdf, ePub, mobi, fb2

ISBN: 9781789990218

Publisher: Games Workshop

 

Ebook magazine downloads Gloomspite English version by Andy Clark

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The Bad Moon looms over the city of Dracothium, and Watch Captain Helena Morthan knows it bodes ill for the town. Can she and grieving warrior Hendrick Saul defeat the plans of the Gloomspite Loonking and save their people? In the dark corners of the Mortal Realms, the mysterious Gloomspite Gitz go to war, following the trail of their abominable deity. Nowhere is beyond the sight of the Bad Moon, not even those places under Sigmar’s protection, like the city of Draconium, sweltering beneath the scalding rain of Aqshy. In this boiling pot of tension, the regent prays to Sigmar for guidance while Captain Helena Morthan puts out fires: blades drawn in the streets, heretical doomsayers preaching the end of days, and insects eating watchmen alive. When the grieving warrior Hendrick and his warband arrive at the gates with a prophetic warning, Captain Morthan sees a way to save her people. But with Skragrott the Loonking plotting underneath Draconium, and the Bad Moon looming in the sky above, will there be a city left to save?
Compliant substrate epitaxy: Au on MoS$_2$
Creators: name: Zhou, Yuzhi
name: Kiriya, Daisuke
name: Haller, Eugene E.
name: Ager, Joel W.
name: Javey, Ali
name: Chrzan, Daryl C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The epitaxial growth of {111} oriented Au on MoS$_2$ is well documented despite the large lattice mismatch (~8% biaxial strain), and the fact that a Au {001} orientation results in much less elastic strain. An analysis based on density functional and linear elasticity theories reveals that the {111} orientation is stabilized by a combination of favorable surface and interfacial contributions to the energy, and the compliance of the first layer of the MoS$_2$.
Additional file 2 of Oral health-related quality of life in 4–16-year-olds with and without juvenile idiopathic arthritis
Creators: name: Gil, Elisabeth G.
name: Skeie, Marit S.
name: Halbig, Josefine
name: Jönsson, Birgitta
name: Lie, Stein Atle
name: Rygg, Marite
name: Fischer, Johannes
name: Rosén, Annika
name: Bletsa, Athanasia
name: Luukko, Keijo
name: Shi, Xie-Qi
name: Frid, Paula
name: Cetrelli, Lena
name: Tylleskär, Karin
name: Rosendahl, Karen
name: Åstrøm, Anne N.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2. Calibration.
Spatial Perception Analysis of the Socio-Economic Effect of Urban Street Crime in the Residential Neighborhoods in Chittagong City, Bangladesh
Creators: name: Haider, Mohammad Ali
Publisher: name: Thammasat Printing House
Year: 2020
Subjects: Chittagong City
Effects of Crime
Residential Neighborhood
Spatial Perception Analysis
Victim of Street Crime

description: International Journal of Building, Urban, Interior and Landscape Technology, 15, , 77-92
PDF EPUB Download Correction: Parole, Prison, and the Possibility of Change by Ben Austen Full Book
Creators: name: Kimberlin
Publisher: name: Zenodo
Year: 2024

description: Correction: Parole, Prison, and the Possibility of Change by Ben Austen

 

 

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Correction: Parole, Prison, and the Possibility of Change

Ben Austen

Page: 336

Format: pdf, ePub, mobi, fb2

ISBN: 9781250758804

Publisher: Flatiron Books

 

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(2816) Mabel Scott
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Decoding Delay Performance of Random Linear Network Coding for Broadcast
Creators: name: Chatzigeorgiou, Ioannis
name: Tassi, Andrea
Publisher: name: arXiv
Year: 2017
Subjects: subject: Information Theory (cs.IT)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Characterization of the delay profile of systems employing random linear network coding is important for the reliable provision of broadcast services. Previous studies focused on network coding over large finite fields or developed Markov chains to model the delay distribution but did not look at the effect of transmission deadlines on the delay. In this work, we consider generations of source packets that are encoded and transmitted over the erasure broadcast channel. The transmission of packets associated to a generation is taken to be deadline-constrained, that is, the transmitter drops a generation and proceeds to the next one when a predetermined deadline expires. Closed-form expressions for the average number of required packet transmissions per generation are obtained in terms of the generation size, the field size, the erasure probability and the deadline choice. An upper bound on the average decoding delay, which is tighter than previous bounds found in the literature, is also derived. Analysis shows that the proposed framework can be used to fine-tune the system parameters and ascertain that neither insufficient nor excessive amounts of packets are sent over the broadcast channel.
description: 10 pages, 8 figures, accepted for publication in the IEEE Transactions on Vehicular Technology
(2817) Alice J Scott
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Dynamic adhesions and MARCKS in melanoma cells
Creators: name: Estrada-Bernal, Adriana
name: Sunpaweravong, Somkiat
name: Gatlin, Jesse C.
name: Pfenninger, Karl H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Cell motility necessitates the rapid formation and disassembly of cell adhesions. We have studied adhesions in a highly motile melanoma cell line using various biochemical approaches and microscopic techniques to image close adhesions. We report that WM-1617 melanoma cells contain at least two types of close adhesion: classic focal adhesions and more extensive, irregularly shaped adhesions that tend to occur along lamellipodial edges. In contrast to focal adhesions, these latter adhesions are highly dynamic and can be disassembled rapidly via protein kinase C (PKC) activation (e.g. by eicosanoid) and MARCKS phosphorylation. MARCKS overexpression, however, greatly increases the area of close adhesions and renders them largely refractory to PKC stimulation. This indicates that nonphosphorylated MARCKS is an adhesion stabilizer. Unlike focal adhesions, the dynamic adhesions contain α3 integrin and MARCKS, but they do not contain the focal adhesion marker vinculin. Overall, these results begin to define the molecular and functional properties of dynamic close adhesions involved in cell motility.
Download PDF The Revenant Games by Margie Fuston
Creators: name: Liao
Publisher: name: Zenodo
Year: 2024

description: The Revenant Games by Margie Fuston

 

 

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The Revenant Games

Margie Fuston

Page: 416

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ISBN: 9781665934411

Publisher: Margaret K. McElderry Books

 

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Novels - upcoming The Revenant Games EPUB PDF Download Read Margie Fuston. Reviews in epub, pdf and mobi formats. Downloading from the publisher The Revenant Games EPUB PDF Download Read Margie Fuston. Download from the publisher EPUB The Revenant Games By Margie Fuston PDF Download iBooks on your Mac or iOS device. Read in your browser PDF The Revenant Games by Margie Fuston EPUB Download Online file sharing and storage, read e-book online. Kindle, iPhone, Android, Symbian, iPad FB2, PDF, Mobi, TXT. Kindle, iPhone, Android, Symbian, iPad FB2, PDF, Mobi, TXT.

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Baryonium, a common ground for atomic and high energy physics
Creators: name: Wycech, S.
name: Dedonder, J. P.
name: Loiseau, B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Indications of the existence of quasi-bound states in the N-Nbar system are presented. Measurements by BES discovered a broad enhancement close to the p-pbar threshold in the S wave, isospin 0 state formed in radiative decays of J/psi. Another enhancement located about 50 MeV below the threshold was found in mesonic decays of J/psi. In terms of the Paris potential model it was shown that these are likely to represent the same state. Antiprotonic atomic data provide some support for this interpretation and indicate the existence of another fairly narrow quasi-bound state in a P wave.
description: 6 pages, 6 figures - Contribution to EXA2014 Vienna to appear in a special edition of Hyperfine Interactions
Download PDF La France avant la France 481-888
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Year: 2024

description: La France avant la France 481-888 pan Geneviève Bührer-Thierry, Charles Mériaux

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La France avant la France 481-888

Geneviève Bührer-Thierry, Charles Mériaux

Nb. de pages: 687

Format: Pdf, ePub, MOBI, FB2

ISBN: 9782701191881

Editeur: Belin

Date de parution: 2014

 

 

 

Télécharger le livre électronique à partir de google books La France avant la France 481-888 9782701191881 (Litterature Francaise) par Geneviève Bührer-Thierry, Charles Mériaux

 

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L'histoire a longtemps juxtaposé des images simples pour définir les quatre siècles écoulés de 481 à 888 : aux Mérovingiens incultes et incapables, succédaient des Carolingiens glorieux et conquérants. Les recherches des dernières décennies, fondées sur une réévaluation des sources écrites et sur les progrès de l'archéologie, ont libéré cette période du carcan des idées reçues. Ce livre, en forme de bilan, dresse des perspectives neuves. Il montre notamment que les rois mérovingiens furent les derniers continuateurs de l'Antiquité et que si les premiers Carolingiens rassemblèrent sous leur autorité presque toute l'Europe occidentale, l'Empire s'avéra une réalité fragile et diverse. Ainsi, les auteurs ramènent-ils les faits aux réalités de l'époque, en rejetant les anachronismes et les outrances, et en appuyant leur exposé sur des textes et des cartes comme sur une iconographie abondante. Cette histoire renouvelée possède un attrait majeur : au-delà des représentations traditionnelles, elle s'efforce d'atteindre le réel.
{pdf download} Le guide de la fermentation du Noma  - Tout commence par le goût
Creators: name: Medrano
Publisher: name: Zenodo
Year: 2024

description: Le guide de la fermentation du Noma - Tout commence par le goût pan René Redzepi, David Zilber

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Le guide de la fermentation du Noma - Tout commence par le goût

René Redzepi, David Zilber

Nb. de pages: 455

Format: Pdf, ePub, MOBI, FB2

ISBN: 9782812319006

Editeur: Chêne (Editions du)

Date de parution: 2018

 

 

 

Téléchargez les nouveaux livres pdf Le guide de la fermentation du Noma - Tout commence par le goût 9782812319006 en francais

 

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Table S1 from Comparative genomic analysis of the ‘psuedofungus’ Hyphochytrium catenoides.
Creators: name: Leonard, Guy
name: Labarre, Aurélie
name: Milner, David S.
name: Monier, Adam
name: Soanes, Darren
name: Wideman, Jeremy G.
name: Maguire, Finlay
name: Stevens, Sam
name: Sain, Divya
name: Grau-Bove, Xavier
name: Arnau Sebe-Pedros
name: Stajich, Jason E.
name: Paszkiewicz, Konrad
name: Brown, Matthew W.
name: Hall, Neil
name: Wickstead, Bill
name: Richards, Thomas A.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences

description: Meiosis specific gene families and their presence in H. catenoides
(2819) Charles Forrester Scott
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Ena/VASP: towards resolving a pointed controversy at the barbed end
Creators: name: Gertler, Frank B.
name: Bear, James E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Ena/VASP proteins are conserved regulators of actin dynamics that have important roles in several physiological processes such as morphogenesis, axon guidance, endothelial barrier function, and cancer cell invasion and metastasis. Although considerable evidence points towards an anti-capping mechanism for Ena/VASP function, some controversy remains. Here, we evaluate the evidence for and against the anti-capping hypothesis, including results from some recent structural and biochemical studies that shed new light on this issue. In addition, we describe several alternate mechanisms that Ena/VASP proteins may utilize to regulate actin dynamics in vivo, including inhibition of branching, bundling and profilin-actin recruitment.
Non-Orthogonal Multiple Access combined with Random Linear Network Coded Cooperation
Creators: name: Khan, Amjad Saeed
name: Chatzigeorgiou, Ioannis
Publisher: name: arXiv
Year: 2017
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: This letter considers two groups of source nodes. Each group transmits packets to its own designated destination node over single-hop links and via a cluster of relay nodes shared by both groups. In an effort to boost reliability without sacrificing throughput, a scheme is proposed, whereby packets at the relay nodes are combined using two methods; packets delivered by different groups are mixed using non-orthogonal multiple access principles, while packets originating from the same group are mixed using random linear network coding. An analytical framework that characterizes the performance of the proposed scheme is developed, compared to simulation results and benchmarked against a counterpart scheme that is based on orthogonal multiple access.
{epub download} L'Art de la guerre
Creators: name: Thomas
Publisher: name: Zenodo
Year: 2024

description: L'Art de la guerre pan Nicolas Machiavel

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L'Art de la guerre

Nicolas Machiavel

Nb. de pages: 279

Format: Pdf, ePub, MOBI, FB2

ISBN: 9782081361126

Editeur: Flammarion

Date de parution: 2015

 

 

 

Ebook pour les téléphones cellulaires téléchargement gratuit L'Art de la guerre

 

Overview

L'Art de la guerre, publié en 1521, occupe une place singulière dans l'oeuvre de Machiavel. Présenté sous la forme d'un dialogue, l'ouvrage surprend par son esprit peu machiavélique. Les considérations tactiques y côtoient les propos consacrés aux nécessités matérielles de la guerre (recrutement, armement.), orchestrant avec subtilité une réflexion sur le pouvoir. Quelles limites la politique impose-t-elle à l'art de la guerre ? Comment définir l'autorité ? Ce sont là quelques-unes des questions soulevées par Machiavel qui puise ici ses modèles chez les Anciens. En grand stratège, il omet parfois de répondre. Mais la guerre est une affaire si sérieuse qu'il faut peut-être savoir la manier avec ironie.
Additional file 5 of Oral health-related quality of life in 4–16-year-olds with and without juvenile idiopathic arthritis
Creators: name: Gil, Elisabeth G.
name: Skeie, Marit S.
name: Halbig, Josefine
name: Jönsson, Birgitta
name: Lie, Stein Atle
name: Rygg, Marite
name: Fischer, Johannes
name: Rosén, Annika
name: Bletsa, Athanasia
name: Luukko, Keijo
name: Shi, Xie-Qi
name: Frid, Paula
name: Cetrelli, Lena
name: Tylleskär, Karin
name: Rosendahl, Karen
name: Åstrøm, Anne N.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 5. Table S1. Categories for Child Oral Impacts on Daily Performances (Child-OIDP) (12–16 years) and questions regarding satisfaction with oral health (global measures), as originally coded and as re-coded for analyses.
Replacing Commercial 6-Phosphofructokinase in an Online Pyrophosphate Detection Assay
Creators: name: Machell, Daniel
name: Hansen, Mathias
name: Cryle, Max
Publisher: name: Monash University
Year: 2023
Subjects: Enzymes
Biocatalysis and enzyme technology
Natural products and bioactive compounds
Proteins and peptides

description: Detection of pyrophosphate is important in quantifying enzyme activity, particularly adenylation domain activity during non-ribosomal peptide synthesis. The previous development of an enzyme coupled PPi/NADH assay allowed the measurement of such activity in an online fashion using commercially available components. Now, with a key enzyme – 6-phosphofructokinase – no longer available, we have screened and identified viable replacement enzymes that can be expressed in high yield and that are far superior in activity to the now discontinued commercial product. This will support the ability of groups to continue to use this established online assay for pyrophosphate detection.
Additional file 4 of Oral health-related quality of life in 4–16-year-olds with and without juvenile idiopathic arthritis
Creators: name: Gil, Elisabeth G.
name: Skeie, Marit S.
name: Halbig, Josefine
name: Jönsson, Birgitta
name: Lie, Stein Atle
name: Rygg, Marite
name: Fischer, Johannes
name: Rosén, Annika
name: Bletsa, Athanasia
name: Luukko, Keijo
name: Shi, Xie-Qi
name: Frid, Paula
name: Cetrelli, Lena
name: Tylleskär, Karin
name: Rosendahl, Karen
name: Åstrøm, Anne N.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 4. Table S1. Categories for Early Childhood Oral Health Impact Scale (ECOHIS) (4–11 years) and questions regarding satisfaction with oral health (global measures), as originally coded and as re-coded for analyses.
[PDF/Kindle] AULA INTERNACIONAL PLUS 4 EDICION ANOTADA PARA DOCENTES descargar gratis
Creators: name: Garcia
Publisher: name: Zenodo
Year: 2024

description: AULA INTERNACIONAL PLUS 4 EDICION ANOTADA PARA DOCENTES de

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Ficha técnica

AULA INTERNACIONAL PLUS 4 EDICION ANOTADA PARA DOCENTES

 

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788418224485

Editorial: DIFUSION CENTRO DE INVESTIGACION Y PUBLICACIONES DE IDIOMAS

Año de edición: 2020

 

 

 

 

 

Revistas de libros electrónicos descarga gratuita pdf AULA INTERNACIONAL PLUS 4 EDICION ANOTADA PARA DOCENTES de 9788418224485 in Spanish

 

Overview

La edición anotada para docentes incluye el libro del alumno completo, anotaciones para llevar a cabo las actividades del manual de manera sencilla y eficaz, las soluciones de las actividades y los ejercicios, las transcripciones de las actividades con audio y vídeo y propuestas de itinerarios opcionales. Itinerario básico. Pensado para avanzar más rápido, este itinerario presenta las actividades imprescindibles para alcanzar los objetivos de cada unidad. Itinerario alternativo. Una propuesta para programar las actividades de manera no lineal secuenciándolas en función de los contenidos que tratan. Itinerario para clases invertidas. Propuestas para aplicar técnicas de flipped classroom en cada unidad.This edition includes notes including the complete studentbook, all the notes performing the activities in the manual in a straightforward and effective way, answers to the activities and exercises, transcriptions of the audio and video activities and optional itinerary proposals. The optional itineraris are designed for faster progress, this itinerary presents the essential activities to achieve the objectives for each unit. Alternative itinerary. A proposal to plan the activities in a non-linear manner by arranging them based on the content they deal with. Itinerary for flipped classrooms. Proposal to apply flipped classroom techniques in each unit.
Figure S1 from Comparative genomic analysis of the ‘psuedofungus’ Hyphochytrium catenoides
Creators: name: Leonard, Guy
name: Labarre, Aurélie
name: Milner, David S.
name: Monier, Adam
name: Soanes, Darren
name: Wideman, Jeremy G.
name: Maguire, Finlay
name: Stevens, Sam
name: Sain, Divya
name: Grau-Bove, Xavier
name: Arnau Sebe-Pedros
name: Stajich, Jason E.
name: Paszkiewicz, Konrad
name: Brown, Matthew W.
name: Hall, Neil
name: Wickstead, Bill
name: Richards, Thomas A.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences

description: Eukaryotic microbes have three primary mechanisms for obtaining nutrients and energy: phagotrophy, photosynthesis and osmotrophy. Traits associated with the latter two functions arose independently multiple times in the eukaryotes. Fungi successfully coupled osmotrophy with filamentous growth, similar traits are also manifested in the Pseudofungi (oomycetes and hyphochytriomycetes). Both the Fungi and the Pseudofungi encompass a diversity of plant and animal parasites. Genome-sequencing efforts have focused on host-associated microbes (mutualistic symbionts or parasites), providing limited comparisons with free-living relatives. Here we report the first draft genome sequence of a hyphochytriomycete ‘pseudofungus’; Hyphochytrium catenoides. Using phylogenomic approaches, we identify genes of recent viral ancestry, with related viral derived genes also present on the genomes of oomycetes, suggesting a complex history of viral coevolution and integration across the Pseudofungi. H. catenoides has a complex life cycle involving diverse filamentous structures and a flagellated zoospore with a single anterior-tinselate flagellum. We use genome comparisons, drug sensitivity analysis and high-throughput culture arrays to investigate the ancestry of oomycete/pseudofungal characteristics and metabolic traits, demonstrating that many of the genetic features associated with pathogenic traits evolved specifically within the oomycete radiation. Comparative genomics also identified differences in the repertoire of genes associated with filamentous growth between the Fungi and the Pseudofungi, including differences in vesicle trafficking systems, cell-wall synthesis pathways and motor protein repertoire, demonstrating that unique cellular systems underpinned the convergent evolution of filamentous osmotrophic growth in these two eukaryotic groups.
Archivierung und Verantwortung
Creators: name: Imeri, Sabine
Publisher: name: Humboldt-Universität zu Berlin
Year: 2018
Subjects: subject: Forschungsdaten
subject: Forschungsdatenmanagement
subject: Ethnologie
subject: Sozialanthropologie
subject: Kulturanthropologie
subject: Archivierung
subject: 020 Bibliotheks- und Informationswissenschaften
subject: 301 Soziologie, Anthropologie

description: In den ethnologischen Fächern stehen dem Interesse, Forschungsdaten langfristig zu sichern, mit Blick auf Nachnutzungsszenarien bzw. -routinen eine Reihe Unklarheiten und Vorbehalte gegenüber: Kontrovers diskutiert werden etwa Formen notwendiger Kontextualisierung sowie – angesichts großer Heterogenität der Datenformen – der Auswahl von Daten zur Archivierung. Besondere Bedeutung kommt Fragen zu Datenschutz und Persönlichkeitsrechten zu, während im Schnittfeld zu forschungsethischen Debatten auch zu erwartende Auswirkungen auf die Feldforschung selbst thematisiert werden. Will man eine breite Akzeptanz von Datenarchivierung und Nachnutzung erreichen, sind die Anforderungen an Professionalität und Vertrauenswürdigkeit künftiger Datenrepositorien entsprechend hoch: Erforderlich sind Lösungen mit ausgeprägter Sensibilität für die Eigenheiten der Wissensproduktion vor allem in der ethnografischen Forschung, wie etwa die geringe Standardisierung, die Individualität der Zugänge und die enge Bindung der forschenden Person an ihr Datenmaterial, aber auch die spezifische Verknüpfung von methodischen und forschungsethischen Fragen. Besondere Bedeutung wird hier Lösungen für den Umgang mit sensiblen Daten, wie sie in sehr vielen ethnografischen Forschungen entstehen, zukommen. Benötigt werden deshalb in erster Linie fachlich spezialisierte Repositorien, die möglichst flexible Prozesse der Archivierung und kontrollierte Prozesse der Nachnutzung genauso anbieten können wie fachspezifische Beratung.