cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains
Creators: name: Craciunescu, Corneliu N.
name: Niculescu, Mihai D.
name: Zeisel, Steven H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The availability of choline during critical periods of fetal development alters hippocampal development and affects memory function throughout life. Choline deficiency during fetal development reduces proliferation and migration of neuronal precursor cells in the mouse fetal hippocampus and these changes are associated with modifications in the protein levels of some cell cycle regulators and early differentiation markers. We fed C57 BL/6 mouse dams diets deficient or normal in choline content from days 12 to 17 of pregnancy, and then collected fetal brains on embryonic day 17. Using laser-capture micro-dissection we harvested cells from the ventricular and subventricular zones of Ammon’s horn and from the prime germinal zone of the dentate gyrus (hippocampus). In the ventricular and subventricular zones from the choline deficient group, we observed increased protein levels for kinase-associated phosphatase (Kap) and for p15INK4b (two cell cycle inhibitors). In the dentate gyrus, we observed increased levels of calretinin (an early marker of neuronal differentiation). In fetal brain from mothers fed a choline deficient diet, DNA global methylation was decreased in the ventricular and subventricular zones of Ammon’s horn. We also observed decreased gene-specific DNA methylation of the gene (Cdkn3) that encodes for Kap, correlating with increased expression of this protein. This was not the case for p15INK4b or calretinin (Cdkn2b and Calb2, respectively). These data suggest that choline deficiency-induced changes in gene methylation could mediate the expression of a cell cycle regulator and thereby alter brain development.
Supplementary Figures from Criticality of plasma membrane lipids reflects activation state of macrophage cells
Creators: name: Cammarota, Eugenia
name: Soriani, Chiara
name: Raphaelle Taub
name: Morgan, Fiona
name: Sakai, Jiro
name: Veatch, Sarah L.
name: Bryant, Clare E.
name: Cicuta, Pietro
Publisher: name: The Royal Society
Year: 2020
Subjects: Biophysics

description: Signalling is of particular importance in immune cells, and upstream in the signalling pathway,, many membrane receptors are functional only as complexes, co-locating with particular lipid species. Work over the last 15 years has shown that plasma membrane lipid composition is close to a critical point of phase separation, with evidence that cells adapt their composition in ways that alter the proximity to this thermodynamic point. Macrophage cells are a key component of the innate immune system, responsive to infections, regulating the local state of inflammation. We investigate changes in the plasma membrane’s proximity to the critical point, as a response to stimulation by various pro- and anti-inflammatory agents. Pro-inflammatory (IFN-γ, Kdo-LipidA, LPS) perturbations induce an increase in the transition temperature of the GMPVs; anti-inflammatory IL4 has the opposite effect. These changes recapitulate complex plasma membrane composition changes, and are consistent with lipid criticality playing a master regulatory role: being closer to critical conditions increases membrane protein activity.
Drifting branches of Crambe maritimaL. with fruits
Creators: name: CADÉE, Gerhard C.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2005

description: The observation of dried branches of Crambe maritima L. in drift along the shore, with fruits still attached, indi-
 cates dispersal by the sea of this coastal plant is not restricted to single drifting fruits, but also occurs as drifting branches
 with the fruits still attached. Along the shore such branches are transported further by the wind as "tumble-weeds", losing
 their fruits during tumbling.
Palaemonella burnsi Holthuis, 1973, a pontoniine shrimp (Crustacea: Decapoda: Palaemonidae) new to the Japanese fauna
Creators: name: BRUCE, Alexander J.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2005

description: The pontoniine shrimp, Palaemonella burnsi, is recorded for the first time outside the Hawaiian Islands.  The
 single specimen, from the Ryukyu Islands, Japan, indicates a considerable extension of the species distribution, that it is
 not an endemic Hawaiian species, and that it may occur in pools on coral reef flats and is not restricted to anchialine habi-
 tats.
Robust Data-Driven Accelerated Mirror Descent
Creators: name: Tan, Hong Ye
name: Mukherjee, Subhadip
name: Tang, Junqi
name: Hauptmann, Andreas
name: Schönlieb, Carola-Bibiane
Publisher: name: arXiv
Year: 2022
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: Learning-to-optimize is an emerging framework that leverages training data to speed up the solution of certain optimization problems. One such approach is based on the classical mirror descent algorithm, where the mirror map is modelled using input-convex neural networks. In this work, we extend this functional parameterization approach by introducing momentum into the iterations, based on the classical accelerated mirror descent. Our approach combines short-time accelerated convergence with stable long-time behavior. We empirically demonstrate additional robustness with respect to multiple parameters on denoising and deconvolution experiments.
description: Note inconsistency with ICASSP paper for step-size choice in (4c) and associated Alg. 1, this version is correct with step-size kt/r
(4277) Eugene Roissard de Belle
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
End-to-end GPU acceleration of low-order-refined preconditioning for high-order finite element discretizations
Creators: name: Pazner, Will
name: Kolev, Tzanio
name: Camier, Jean-Sylvain
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mathematical Software (cs.MS)
subject: Numerical Analysis (math.NA)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: In this paper, we present algorithms and implementations for the end-to-end GPU acceleration of matrix-free low-order-refined preconditioning of high-order finite element problems. The methods described here allow for the construction of effective preconditioners for high-order problems with optimal memory usage and computational complexity. The preconditioners are based on the construction of a spectrally equivalent low-order discretization on a refined mesh, which is then amenable to, for example, algebraic multigrid preconditioning. The constants of equivalence are independent of mesh size and polynomial degree. For vector finite element problems in $H({\rm curl})$ and $H({\rm div})$ (e.g. for electromagnetic or radiation diffusion problems) a specially constructed interpolation-histopolation basis is used to ensure fast convergence. Detailed performance studies are carried out to analyze the efficiency of the GPU algorithms. The kernel throughput of each of the main algorithmic components is measured, and the strong and weak parallel scalability of the methods is demonstrated. The different relative weighting and significance of the algorithmic components on GPUs and CPUs is discussed. Results on problems involving adaptively refined nonconforming meshes are shown, and the use of the preconditioners on a large-scale magnetic diffusion problem using all spaces of the finite element de Rham complex is illustrated.
description: 23 pages, 13 figures
Supplementary material for Fluid and Solute Transport across the Retinal Pigment Epithelium: a Theoretical Model from Fluid and solute transport across the retinal pigment epithelium: a theoretical model.
Creators: name: Mariia Dvoriashyna
name: Foss, Alexander J. E.
name: Gaffney, Eamonn A.
name: Repetto, Rodolfo
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Biophysics
subject: 110601 Biomechanics
subject: FOS: Health sciences
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: Derivation of simplified model in the cell and cleft, choice of model parameters
Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation
Creators: name: Tzima, Ellie
name: Irani-Tehrani, Mohamad
name: Liu, Yunhao
name: Maeda, Nobuyo
name: Sweet, Daniel Timothy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Atherosclerotic plaques develop in regions of the vasculature associated with chronic inflammation due to disturbed flow patterns. Endothelial phenotype modulation by flow requires the integration of numerous mechanotransduction pathways, but how this is achieved is not well understood. We show here that, in response to flow, the adaptor protein Shc is activated and associates with cell–cell and cell–matrix adhesions. Shc activation requires the tyrosine kinases vascular endothelial growth factor receptor 2 and Src. Shc activation and its vascular endothelial cadherin (VE-cadherin) association are matrix independent. In contrast, Shc binding to integrins requires VE-cadherin but occurs only on specific matrices. Silencing Shc results in reduction in both matrix-independent and matrix-dependent signals. Furthermore, Shc regulates flow-induced inflammatory signaling by activating nuclear factor κB–dependent signals that lead to atherogenesis. In vivo, Shc is activated in atherosclerosis-prone regions of arteries, and its activation correlates with areas of atherosclerosis. Our results support a model in which Shc orchestrates signals from cell–cell and cell–matrix adhesions to elicit flow-induced inflammatory signaling.
Holoplanktonic polychaetes from the Gulf of Tehuantepec, Mexico
Creators: name: FERNÁNDEZ-ÁLAMO, Maria Ana
name: SANVICENTE-AÑORVE, Laura
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2005

description: Composition, abundance, and main assemblages of holoplanktonic polychaetes were analysed in the Gulf of
 Tehuantepec. This Gulf, in Mexican waters of the eastern tropical Pacific, is a very productive system due to an upwelling
 during the winter. Zooplankton samples were taken over a station grid covering neritic and oceanic waters during March
 and November 1978. Most species showed their highest densities in the oceanic region. In the western Gulf, the area sam-
 pled in both seasons, mean polychaete abundance was higher in November (549.2 ind.1000 m-3) than in March (143.8
 ind.1000 m-3). A regression tree analysis showed that pH and dissolved oxygen were the main factors affecting the total
 polychaete abundance over the study area during March. Identified families were: Lopadorhynchidae (88.8%), Alciopidae
 (6.6%), Iospilidae (2.8%), Tomopteridae (1.1%) and Typhloscolecidae (0.7%). The dominant species, Pelagobia longicir-
 rata, accounted for 86.5% of the total polychaete abundance. A Bray-Curtis analysis identified two main polychaete assem-
 blages during March: "oceanic" and "neritic". Species richness and mean polychaete abundance were higher in the
 "oceanic" assemblage, and P. longicirrata, Plotohelmis capitata, Rhynchonerella gracilis and Lopadorhynchus henseni
 were the most frequent and abundant species in this assemblage. In the "neritic" assemblage, the iospilids Phalacrophorus
 uniformis and Iospilus phalacroides registered the highest relative abundance. It is suggested that the structure of holo-
 planktonic polychaete assemblages could be determined by the feeding habits of the species and their tolerance to the varia-
 bility in environmental conditions.
(4279) Jean Roissard de Belle
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Standard Electroweak Interactions in Gravitational Theory with Chameleon Field and Torsion
Creators: name: Ivanov, A. N.
name: Wellenzohn, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We propose a version of a gravitational theory with the torsion field, induced by the chameleon field. Following Hojman et al. Phys. Rev. D17, 3141 (1976) the results, obtained in Phys. Rev. D90, 045040 (2014), are generalised by extending the Einstein gravity to the Einstein-Cartan gravity with the torsion field as a gradient of the chameleon field through a modification of local gauge invariance of minimal coupling in the Weinberg-Salam electroweak model. The contributions of the chameleon (torsion) field to the observables of electromagnetic and weak processes are calculated. Since in our approach the chameleon-photon coupling constant beta_(gamma) is equal to the chameleon-matter coupling constant beta, i.e. beta_(gamma) = beta, the experimental constraints on beta, obtained in terrestrial laboratories by T. Jenke et al. (Phys. Rev. Lett. 112, 115105 (2014)) and by H. Lemmel et al. (Phys. Lett. B743, 310 (2015)), can be used for the analysis of astrophysical sources of chameleons, proposed by C. Burrage et al. (Phys. Rev. D79, 044028 (2009)), A.-Ch. Davis et al. (Phys. Rev. D80, 064016 (2009), and in references therein, where chameleons induce photons because of direct chameleon-photon transitions in the magnetic fields.
description: 26 pages, 8 figures
Long Patch Base Excision Repair Proceeds via Coordinated Stimulation of the Multienzyme DNA Repair Complex
Creators: name: Sancar, Aziz
name: Bambara, Robert A.
name: Lindsey-Boltz, Laura A.
name: Balakrishnan, Lata
name: Brandt, Patrick D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Base excision repair, a major repair pathway in mammalian cells, is responsible for correcting DNA base damage and maintaining genomic integrity. Recent reports show that the Rad9-Rad1-Hus1 complex (9-1-1) stimulates enzymes proposed to perform a long patch-base excision repair sub-pathway (LP-BER), including DNA glycosylases, apurinic/apyrimidinic endonuclease 1 (APE1), DNA polymerase β (pol β), flap endonuclease 1 (FEN1), and DNA ligase I (LigI). However, 9-1-1 was found to produce minimal stimulation of FEN1 and LigI in the context of a complete reconstitution of LP-BER. We show here that pol β is a robust stimulator of FEN1 and a moderate stimulator of LigI. Apparently, there is a maximum possible stimulation of these two proteins such that after responding to pol β or another protein in the repair complex, only a small additional response to 9-1-1 is allowed. The 9-1-1 sliding clamp structure must serve primarily to coordinate enzyme actions rather than enhancing rate. Significantly, stimulation by the polymerase involves interaction of primer terminus-bound pol β with FEN1 and LigI. This observation provides compelling evidence that the proposed LP-BER pathway is actually employed in cells. Moreover, this pathway has been proposed to function by sequential enzyme actions in a “hit and run” mechanism. Our results imply that this mechanism is still carried out, but in the context of a multienzyme complex that remains structurally intact during the repair process.
Aberrant Estrogen Regulation of PEMT Results in Choline Deficiency-associated Liver Dysfunction
Creators: name: Zeisel, Steven H.
name: Galanko, Joseph A.
name: Patel, Mukund
name: Davis, Ian J.
name: Resseguie, Mary E.
name: Da Costa, Kerry Ann
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: When dietary choline is restricted, most men and postmenopausal women develop multiorgan dysfunction marked by hepatic steatosis (choline deficiency syndrome (CDS)). However, a significant subset of premenopausal women is protected from CDS. Because hepatic PEMT (phosphatidylethanolamine N-methyltransferase) catalyzes de novo biosynthesis of choline and this gene is under estrogenic control, we hypothesized that there are SNPs in PEMT that disrupt the hormonal regulation of PEMT and thereby put women at risk for CDS. In this study, we performed transcript-specific gene expression analysis, which revealed that estrogen regulates PEMT in an isoform-specific fashion. Locus-wide SNP analysis identified a risk-associated haplotype that was selectively associated with loss of hormonal activation. Chromatin immunoprecipitation, analyzed by locus-wide microarray studies, comprehensively identified regions of estrogen receptor binding in PEMT. The polymorphism (rs12325817) most highly linked with the development of CDS (p < 0.00006) was located within 1 kb of the critical estrogen response element. The risk allele failed to bind either the estrogen receptor or the pioneer factor FOXA1. These data demonstrate that allele-specific ablation of estrogen receptor-DNA interaction in the PEMT locus prevents hormone-inducible PEMT expression, conferring risk of CDS in women.
Alimentation et condition de la dorade Sparus aurata (Teleostei: Sparidae) dans la lagune du Mellah (Algérie Nord-Est)
Creators: name: CHAOU, Lamya
name: DERBAL, Farid
name: KARA, M. Hichem
name: QUIGNARD, Jean Pierre
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2005

description: Dietary habits and condition of gilt-head sea bream Sparus aurata (Teleostei: Sparidae) in the Mellah lagoon
 (North-Eastern Algeria). The feeding habits of Sparus aurata in the Mellah lagoon (northeastern Algeria) was studied using
 three simple methods (frequency of occurrence of prey, numeric percentage and percentage weight) and a feeding coeffi-
 cient. Monthly variations in the stomach vacuity were also examined. The diet includes a wide variety of food organisms,
 fish and molluscs bivalvia constituting the favorite preys. A relationship between feeding activity and body condition was
 observed.
Supplementary material for Fluid and Solute Transport across the Retinal Pigment Epithelium: a Theoretical Model from Fluid and solute transport across the retinal pigment epithelium: a theoretical model
Creators: name: Mariia Dvoriashyna
name: Foss, Alexander J. E.
name: Gaffney, Eamonn A.
name: Repetto, Rodolfo
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Biophysics
subject: 110601 Biomechanics
subject: FOS: Health sciences
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: Derivation of simplified model in the cell and cleft, choice of model parameters
Influence of a tropical lagoon discharge anddepth on the structure of adjacent shelf macroinfauna (Southern Caribbean)
Creators: name: GUZMÁN-ALVIS, Angela I.
name: CARRASCO, Franklin D.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2005

description: At the outlet of rivers and coastal lagoons, the distribution of benthic organisms is affected by depth, variations
 in sediment composition and salinity. This relationship was assessed in the area influenced by the discharge from a tropi-
 cal coastal lagoon (Ciénaga Grande de Santa Marta, Colombia) analyzing the taxonomic and trophic structure of the asso-
 ciations. The abundance, biomass and trophic guilds of the macroinfauna were related to physical and chemical variables
 (turbid-water conditions, salinity, dissolved oxygen, temperature, silt and organic contents in sediment) using univariate
 tests and multivariate analysis. Assemblages differing in density, richness, abundance-biomass relation and trophic groups
 were found; these differences were all related to the distance from the lagoon and to depth. Taxonomic and trophic struc-
 ture of assemblages did not change seasonally. Biological variability was high, correlated with the distance from the lagoon
 outlet and the depth affecting the grain size and the organic content in the sediment. This suggested that taxonomic and
 trophic structure was more affected by spatial variation than by temporal variation, which was determined by the sediment
 heterogeneity related to the discharge from the lagoon and to depth.
Infants Perceived as "Fussy" Are More Likely to Receive Complementary Foods Before 4 Months
Creators: name: Slining, Meghan
name: Goldman, Barbara Davis
name: Bentley, Margaret
name: Adair, Linda
name: Borja, Judith
name: Thompson, Amanda
name: Wasser, Heather
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Our purpose was to assess early infant-feeding patterns in a cohort of low-income black mothers and to examine associations between maternal perception of infant temperament and complementary feeding (CF) before 4 months.
USING GIS TO CREATE AN AGRO-CLIMATIC ZONE MAP FOR SOROTI DISTRICT
Creators: name: Balungi Francis
Publisher: name: Zenodo
Year: 2017
Subjects: Geospatial application
Gis
agriculture

description: This project examines the use of GIS in creating an agro-climatic zone map. The map recognizes that the major aspects of climate that affect plant growth are moisture availability and temperature. The agro-climatic zones are therefore specific combinations of moisture availability zones and temperature zones. The project was undertaken following the variability of rainfall and recurrent droughts in the country that affects the lives of millions of people whose livelihood is mainly dependent on agriculture. The project is of much importance as it is aimed at showing areas that are climatologically suitable for particular crops and also as a guide to the work of planners and farmers. The goal of this study is to extrapolate empirical research findings from the map for agric-environmental experimental design and as a framework for assessment of the impact of climate change on Soroti region agriculture. The objectives were achieved using Idris32 software incorporating various methods. A temperature map was created from a derived relationship (regression equation) between temperature and elevation using tabular temperature and elevation data obtained from four weather stations. The temperature zones were created by reclassifyng the temperature map. An evaporation map was created using a published relation ship between evaporation and temperature. The moisture availability map was created by getting the ratio of rainfall map to evaporation. Moisture zones were created by reclassifying the moisture availability map. An agro climatic zone map was then created through a combination of the temperature zones with the moisture zones. The agro climatic zone map was classified using the Köppen and Thornthwaite agro climatic classification system. Finally crop growth in each zone was selected through a comparison of the temperature and moisture requirements for each crop based on published FAO data (climatic adaptability of crops) with the prevailing temperature and moisture conditions in each zone. The agro climatic zones were suitable for the growth of cassava, sweet potatoes, rice, sorghum, maize, millet and ground nuts. The results show that zones in the humid and dry-sub humid regions are highly suitable for agricultural production than those in the semi arid regions. The results are recommended for use on a lager scale only if they are accurate and representative of the climatic conditions in the selected region of the country. However if many alternatives are to be included based on the stated criterion, an Agro-Ecological Zone map should be created.
Choline Dehydrogenase Polymorphism rs12676 Is a Functional Variation and Is Associated with Changes in Human Sperm Cell Function
Creators: name: Zeisel, Steven H.
name: Johnson, Amy R.
name: Wang, Tongwen
name: Galanko, Joseph A.
name: Lao, Sai
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Approximately 15% of couples are affected by infertility and up to half of these cases arise from male factor infertility. Unidentified genetic aberrations such as chromosomal deletions, translocations and single nucleotide polymorphisms (SNPs) may be the underlying cause of many cases of idiopathic male infertility. Deletion of the choline dehydrogenase (Chdh) gene in mice results in decreased male fertility due to diminished sperm motility; sperm from Chdh−/− males have decreased ATP concentrations likely stemming from abnormal sperm mitochondrial morphology and function in these cells. Several SNPs have been identified in the human CHDH gene that may result in altered CHDH enzymatic activity. rs12676 (G233T), a non-synonymous SNP located in the CHDH coding region, is associated with increased susceptibility to dietary choline deficiency and risk of breast cancer. We now report evidence that this SNP is also associated with altered sperm motility patterns and dysmorphic mitochondrial structure in sperm. Sperm produced by men who are GT or TT for rs12676 have 40% and 73% lower ATP concentrations, respectively, in their sperm. rs12676 is associated with decreased CHDH protein in sperm and hepatocytes. A second SNP located in the coding region of IL17BR, rs1025689, is linked to altered sperm motility characteristics and changes in choline metabolite concentrations in sperm.
Electrochemical Shot-Noise of a Redox Monolayer
Creators: name: Grall, Simon
name: Li, Shuo
name: Jalabert, Laurent
name: Kim, Soo-Hyeon
name: Chovin, Arnaud
name: Demaille, Christophe
name: Clement, Nicolas
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Redox monolayers are the base for a wide variety of devices including high-frequency molecular diodes or biomolecular sensors. We introduce a formalism to describe the electrochemical shot-noise of such monolayer, confirmed experimentally at room temperature in liquid. The proposed method, carried out at equilibrium, avoids parasitic capacitance, increases the sensitivity and allows to obtain quantitative information such as the electronic coupling (or standard electron transfer rates), its dispersion and the number of molecules. Unlike in solid-state physics, the homogeneity in energy levels and transfer rates in the monolayer yields a Lorentzian spectrum. This first step for shot-noise studies in molecular electrochemical systems opens perspectives for quantum transport studies in liquid environment at room temperature as well as highly sensitive measurements for bioelectrochemical sensors.
description: 6 pages, 4 Figures (main) + 15 pages, 11 Figures (SM)
A new species of Glochinema (Epsilonematidae: Nematoda) from the oxygen minimum zone off Baja California, NE Pacific and phylogenetic relationships at species level within the family
Creators: name: NEIRA, Carlos
name: DECRAEMER, Wilfrida
name: BACKELJAU, Thierry
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2005

description: Glochinema spinithorni sp. nov. is described from muddy, bathyal sediments of the oxygen minimum zone
 (OMZ) of the north eastern Pacific Ocean off Baja California. It is characterized by a rather large body length (over 1 mm),
 a large number of body rings (242-282), sexual dimorphism in the number and position of pharyngeal thorns near the head
 region, cuticular ornamentation with numerous hairy spines and two sets of stronger spines ventrally in the anterior body
 half, mid-sized spiral amphids, and by the number and arrangement of ambulatory setae and long spicules (over 100 µm).
 The finding of a second OMZ Glochinema species with similar morphological characteristics supports the presumption that
 OMZs function as isolated habitats promoting endemism at low taxonomic levels. Results of phylogenetic analyses at the
 species level restricted to the Glochinematinae and Keratonematinae suggest that both OMZ species form a monophyletic
 group. An attempt was made to recognize phylogenetic relationships at species level within the family. The phylogenetic
 analyses were based upon a data matrix of 96 ingroup taxa and 25 characters. The results support the monophyly of the
 genera Leptepsilonema, Metepsilonema, Perepsilonema and Polkepsilonema (with or without Pternepsilonema).
Composition and endemism of the deep-sea hydrothermal vent fauna
Creators: name: WOLFF, Torben
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2005

description: Based on enumerations from 1997/1998 and personal records, an up-to-date survey of the hydrothermal vent
 fauna is presented with number of species, genera and families of various taxa. The number of recorded species is 712 and
 includes species known exclusively from vents (71%), also occurring in cold seeps and/or whale falls (5%), also recorded
 from non-vent/non-seep environments (9%) or mainly referred to genus only (15%). The number of genera is 373, of fami-
 lies 185. Molluscs, arthropods and polychaetes are the prevailing groups (36, 34 and 18%, respectively). Prosobranch gas-
 tropods number almost three fourths of 257 mollusc species, copepods more than one third of 225 crustaceans and phyl-
 lodocid polychaetes more than half of 129 polychaetes. Calculation of vent endemism (after deduction of 103 species of
 doubtful status) shows values far exceeding those found elsewhere in the marine environment. On species level it is 83.4%,
 with maximum values found in cirripeds (100%), copepods (98%), prosobranch gastropods (89%), and polychaetes (86%).
 The percentage of endemic genera is 45. All six cirriped and most vestimentiferan genera are endemic, and other high val-
 ues are within copepods (66%), gastropods (58%), polychaetes (51%) and decapod crustaceans (43%). Fourteen among the
 families (8%) are found in vents exclusively, eight also in seeps.
INCIDENCE OF MUSSEL CULTURE IN THE DIET OF LIOCARCINUS-DEPURATOR (L) (BRACHYURA, PORTUNIDAE) IN THE RIA-DE-AROUSA (GALICIA, NW SPAIN)
Creators: name: Gonzalezgurriaran, E.
name: Freire, J.
name: Fernandez, L.
name: Poza, E.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1989

Abstract
(4286) John Findlay
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
PARAFAC2-based Coupled Matrix and Tensor Factorizations
Creators: name: Schenker, Carla
name: Wang, Xiulin
name: Acar, Evrim
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Optimization and Control (math.OC)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Coupled matrix and tensor factorizations (CMTF) have emerged as an effective data fusion tool to jointly analyze data sets in the form of matrices and higher-order tensors. The PARAFAC2 model has shown to be a promising alternative to the CANDECOMP/PARAFAC (CP) tensor model due to its flexibility and capability to handle irregular/ragged tensors. While fusion models based on a PARAFAC2 model coupled with matrix/tensor decompositions have been recently studied, they are limited in terms of possible regularizations and/or types of coupling between data sets. In this paper, we propose an algorithmic framework for fitting PARAFAC2-based CMTF models with the possibility of imposing various constraints on all modes and linear couplings, using Alternating Optimization (AO) and the Alternating Direction Method of Multipliers (ADMM). Through numerical experiments, we demonstrate that the proposed algorithmic approach accurately recovers the underlying patterns using various constraints and linear couplings.
Energieeffizienz im Kontext unternehmerischer Klimaschutzstrategien : Verringerung von Informationsdefiziten und Miteinbezug industrieller Wertschöpfungsketten
Creators: name: Ebersold, Felix
Publisher: name: Universität Kassel
Year: 2022
Subjects: subject: Klimaschutz
subject: Klimaneutralität
subject: Industrie
subject: Energieeffizienz
subject: Insetting
subject: Digitalisierung
subject: 333
subject: Energieeffizienz
subject: Klimaschutz
subject: Wertschöpfungskette
subject: Unvollkommene Information
subject: Emissionsverringerung
subject: Potenzialanalyse
subject: Benchmarking

description: Zugleich: Dissertation, Universität Kassel, 2021
Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise
Creators: name: Willis, Monte S.
name: Wadosky, Kristine M.
name: Wang, Shaobin
name: Mcdonough, Holly
name: Patterson, Cam
name: Min, Jin Na
name: Lockyer, Pamela
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The carboxyl terminus of HSP70-interacting protein (CHIP) is a ubiquitin ligase/co-chaperone critical for the maintenance of cardiac function. Mice lacking CHIP (CHIP −/−) suffer decreased survival, enhanced myocardial injury, and increased arrhythmias compared to wild type controls following challenge with cardiac ischemia reperfusion injury. Recent evidence implicates a role for CHIP in chaperone-assisted selective autophagy, a process that is associated with exercise-induced cardioprotection. To determine whether CHIP is involved in cardiac autophagy, we challenged CHIP −/− mice with voluntary exercise. CHIP −/− mice respond to exercise with an enhanced autophagic response that is associated with an exaggerated cardiac hypertrophy phenotype. No impairment of function was identified in the CHIP −/− mice by serial echocardiography over the five weeks of running, indicating that the cardiac hypertrophy was physiologic not pathologic in nature. It was further determined that CHIP plays a role in inhibiting Akt signaling and autophagy determined by autophagic flux in cardiomyocytes and in the intact heart. Taken together, cardiac CHIP appears to play a role in regulating autophagy during the development of cardiac hypertrophy, possibly by its role in supporting Akt signaling, induced by voluntary running in vivo.
Is $Λ$CDM an effective CCDM cosmology?
Creators: name: Lima, J. A. S.
name: Santos, R. C.
name: Cunha, J. V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We show that a cosmology driven by gravitationally induced particle production of all non-relativistic species existing in the present Universe mimics exactly the observed flat accelerating $Λ$CDM cosmology with just one dynamical free parameter. This kind of scenario includes the creation cold dark matter (CCDM) model [Lima, Jesus & Oliveira, JCAP 011(2010)027] as a particular case and also provides a natural reduction of the dark sector since the vacuum component is not needed to accelerate the Universe. The new cosmic scenario is equivalent to $Λ$CDM both at the background and perturbative levels and the associated creation process is also in agreement with the universality of the gravitational interaction and equivalence principle. Implicitly, it also suggests that the present day astronomical observations cannot be considered the ultimate proof of cosmic vacuum effects in the evolved Universe because $Λ$CDM may be only an effective cosmology.
description: 6 pages, 2 figures, changes in the abstract, introduction, new references and typo corrections
Structural Determinants of RGS-RhoGEF Signaling Critical to  Entamoeba histolytica  Pathogenesis
Creators: name: Kimple, Adam J.
name: Muller, Robin E.
name: Manning, Alyssa J.
name: MacHius, Mischa
name: Siderovski, David P.
name: Rogers, Stephen L.
name: Willard, Francis S.
name: Bosch, Dustin E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: G-protein signaling pathways, as key components of physiologic responsiveness and timing, are frequent targets for pharmacologic intervention. Here, we identify an effector for heterotrimeric G-protein α subunit (EhGα1) signaling from Entamoeba histolytica, the causative agent of amoebic colitis. EhGα1 interacts with this effector and GTPase-accelerating protein (GAP), EhRGS-RhoGEF, in a nucleotide state-selective fashion. Co-expression of EhRGS-RhoGEF with constitutively active EhGα1 and EhRacC leads to Rac-dependent spreading in Drosophila S2 cells. EhRGS-RhoGEF overexpression in E. histolytica trophozoites leads to reduced migration toward serum and lower cysteine protease activity, as well as reduced attachment to, and killing of, host cells. A 2.3 Å crystal structure of the full-length EhRGS-RhoGEF reveals a putative inhibitory helix engaging the DH domain Rho-binding surface and the PH domain. Mutational analysis of the EhGα1/EhRGS-RhoGEF interface confirms a canonical RGS domain rather than a RhoGEF-RGS (“rgRGS”) domain, suggesting a convergent evolution toward heterotrimeric and small G-protein cross-talk.
Capacity and Power Scaling Laws for Finite Antenna MIMO Amplify-and-Forward Relay Networks
Creators: name: Simmons, David
name: Coon, Justin P.
name: Warsi, Naqueeb
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: In this paper, we present a novel framework that can be used to study the capacity and power scaling properties of linear multiple-input multiple-output (MIMO) $d\times d$ antenna amplify-and-forward (AF) relay networks. In particular, we model these networks as random dynamical systems (RDS) and calculate their $d$ Lyapunov exponents. Our analysis can be applied to systems with any per-hop channel fading distribution, although in this contribution we focus on Rayleigh fading. Our main results are twofold: 1) the total transmit power at the $n$th node will follow a deterministic trajectory through the network governed by the network's maximum Lyapunov exponent, 2) the capacity of the $i$th eigenchannel at the $n$th node will follow a deterministic trajectory through the network governed by the network's $i$th Lyapunov exponent. Before concluding, we concentrate on some applications of our results. In particular, we show how the Lyapunov exponents are intimately related to the rate at which the eigenchannel capacities diverge from each other, and how this relates to the amplification strategy and number of antennas at each relay. We also use them to determine the extra cost in power associated with each extra multiplexed data stream.
description: 16 pages, 9 figures. Accepted for publication in IEEE Transactions on Information Theory
Is the degree of food processing and convenience linked with the nutritional quality of foods purchased by US households?
Creators: name: Poti, Jennifer M.
name: Mendez, Michelle A.
name: Ng, Shu Wen
name: Popkin, Barry M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Background: “Processed foods” are defined as any foods other than raw agricultural commodities and can be categorized by the extent of changes occurring in foods as a result of processing. Conclusions about the association between the degree of food processing and nutritional quality are discrepant.
Electronic Supplementary Material from Analysis of statistical correlations between properties of adaptive walks in fitness landscapes.
Creators: name: Reia, Sandro M.
name: Campos, Paulo R. A.
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Computational Biology
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: This electronic supplementary material provides additional figures of the mutational pathways for the Gb1 and NK fitness landscapes, as well as additional correlation tables.
An Ethnographic Study of Stigma and Ageism in Residential Care or Assisted Living
Creators: name: Rubinstein, Bob
name: Clark, Leanne
name: Zimmerman, Sheryl
name: Dobbs, Debra
name: Eckert, J. Kevin
name: Keimig, Lynn
name: Frankowski, Ann Christine
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: This study explored aspects of stigmatization for older adults who live in residential care or assisted living (RC–AL) communities and what these settings have done to address stigma. Design and recognition of resident preferences and strengths, rather than their limitations.
Relaxation dynamics of local observables in integrable systems
Creators: name: De Nardis, Jacopo
name: Piroli, Lorenzo
name: Caux, Jean-Sébastien
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We show, using the quench action approach [Caux&Essler Phys. Rev. Lett. 110 (2013)], that the whole post-quench time evolution of an integrable system in the thermodynamic limit can be computed with a minimal set of data which are encoded in what we denote the generalized single-particle overlap coefficient $s_0^{Ψ_0}(λ)$. This function can be extracted from the thermodynamically leading part of the overlaps between the eigenstates of the model and the initial state. For a generic global quench the shape of $s_0^{Ψ_0}(λ)$ in the low momentum limit directly gives the exponent for the power law decay to the effective steady state. As an example we compute the time evolution of the static density-density correlation in the interacting Lieb-Liniger gas after a quench from a Bose-Einstein condensate. This shows an approach to equilibrium with power law $t^{-3}$ which turns out to be independent of the post-quench interaction and of the considered observable.
description: 6 pages, 2 figures
Superconducting microsphere magnetically levitated in an anharmonic potential with integrated magnetic readout
Creators: name: Latorre, Martí Gutierrez
name: Higgins, Gerard
name: Paradkar, Achintya
name: Bauch, Thilo
name: Wieczorek, Witlef
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Magnetically levitated superconducting microparticles offer a promising path to quantum experiments with picogram to microgram objects. In this work, we levitate a 700ng $\sim 10^{17}$amu superconducting microsphere in a magnetic chip trap in which detection is integrated. We measure the particle's center-of-mass motion using a DC-SQUID magnetometer. The trap frequencies are continuously tunable between 30 and 160 Hz and the particle remains stably trapped over days in a dilution refrigerator environment. We characterize motional-amplitude-dependent frequency shifts, which arise from trap anharmonicities, namely Duffing nonlinearities and mode couplings. We explain this nonlinear behavior using finite element modelling of the chip-based trap potential. This work constitutes a first step towards quantum experiments and ultrasensitive inertial sensors with magnetically levitated superconducting microparticles.
description: version close to published version; 16 pages, 13 figures
(4275) Laughton
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Electronic Supplementary Material from Analysis of statistical correlations between properties of adaptive walks in fitness landscapes
Creators: name: Reia, Sandro M.
name: Campos, Paulo R. A.
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Computational Biology
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: This electronic supplementary material provides additional figures of the mutational pathways for the Gb1 and NK fitness landscapes, as well as additional correlation tables.
Dying With Dementia in Long-Term Care
Creators: name: Hanson, Laura C.
name: Williams, Christianna S.
name: Sloane, Philip D.
name: Zimmerman, Sheryl
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: To better understand the experiences and potential unmet need of persons with dementia who die in long-term care.
Supplementary Information from Continent-wide effects of urbanization on bird and mammal genetic diversity.
Creators: name: C. Schmidt
name: M. Domaratzki
name: R. P. Kinnunen
name: J. Bowman
name: C. J. Garroway
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology

description: Includes detailed methods, supplementary figures, list of included data, and data citations.
Dissipation and velocity distribution at the shear-driven jamming transition
Creators: name: Olsson, Peter
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We investigate energy dissipation and the distribution of particle velocities at the jamming transition for overdamped shear-driven frictionless disks in two dimensions at zero temperature. We find that the dissipation is caused by the fastest particles and that the fraction of particles responsible for the dissipation decreases towards zero as jamming is approached. These particles belong to an algebraic tail of the velocity distribution that approaches $\sim v^{-3}$ as jamming is approached. We further find that different measures of the velocity diverge differently, which means that concepts like "typical velocity" may no longer be used---a finding that should have implications for analytical approaches to shear-driven jamming.
description: Thoroughly rewritten with new analytical work as Supplemental material