cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Sustained Medication Reduction Following Unilateral VIM Thalamic Stimulation for Essential Tremor
Creators: name: Resnick, Andrew S.
name: Okun, Michael S.
name: Malapira, Teresita
name: Smith, Donald
name: Vale, Fernando L.
name: Sullivan, Kelly
name: Miller, Amber
name: Jahan, Israt
name: Zesiewicz, Theresa Ann
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2012

description: Background: Deep brain stimulation (DBS) is an increasingly utilized therapeutic modality for the management of medication refractory essential tremor (ET). The aim of this study was to determine whether DBS allowed for anti-tremor medication reduction within the year after the procedure was performed. Methods: We conducted a retrospective chart review and telephone interviews on 34 consecutive patients who had been diagnosed with ET, and who had undergone unilateral DBS surgery. Results: Of the 34 patients in our cohort, 31 patients (91%) completely stopped all anti-tremor medications either before surgery (21 patients, 62%) or in the year following DBS surgery (10 patients, 29%). Patients who discontinued tremor medications before DBS surgery did so because their tremors either became refractory to anti-tremor medication, or they developed adverse events to tremor medications. Patients who stopped tremor medications after DBS surgery did so due to sufficient tremor control. Only three patients (9%) who were taking tremor medications at the time of surgery continued the use of a beta-blocker post-operatively for the purpose of hypertension management in all cases. Discussion: The data from this study indicate that medication cessation is common following unilateral DBS for ET.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Le psychocritique du fantome dans la poesie et le theatre du xx siecle
Creators: name: Καρκάνη, Παναγιώτα Α.
Publisher: name: Aristotle University of Thessaloniki
Year: 2006
Subjects: Μυθικές φιγούρες/πλάσματα της φαντασίας
Ποιητικό Εγώ/Είδωλο του βιογραφικού Εγώ
Visible/Invisible phantoms
Poetic I : Phantom

description: Μέσω της ψυχιατρικής μελέτης ποιητικών και θεατρικών έργων του 20ου αιώνα, το φάντασμα ανάγεται σε κυρίαρχη μυθική φιγούρα που ξεπηδά μέσα από το ασυνείδητο του δημιουργού-εκφράζοντας το αντικείμενο επιθυμίας του-, ταλαντέυεται ανάμεσα στο όνειρο και την πραγματικότητα και η δράση του δε γνωρίζει όρια καθώς δημιουργεί μία συμπαντική πραγματικότητα. Δεν είναι παραδοσιακό φάντασμα αλλά χαρακτηρίζεται έτσι γιατί είναι πλάσμα της φαντασίας και έζω από το ανθρώπινο. Η μελέτη καταδεικνύει πως σε ένα έργο συναντάμε πολλά φαντάσματα απουσίας ατόμων και πραγμάτων μεταμορφώνοντας και το ποιητικό Εγώ σε άλλον/φάντασμα. Επίσης δεν περιορίζονται στο ρόλο ενός προσώπου αλλά μπορούν να αναπαραστήσουν λειτουργίες, λογοτεσνική, ηθική και αρχετυπική. Τελικά το φάντασμα θα μπορούσε να οριστεί ως μία φιγούρα απογυμνωμένη από όλες τις σημασίες, η οποία αποκτά αυτόματα μέσα στα κείμενα, ως μέσο αναπαραστάσεως ενός παιδικού τραύματος, μιας ανεκπλήρωτης επιθυμίας, ενός ηθικού μηνύματος, ενός αρχετύπου
description: The application of psychocritism in 20th century's poetry and theater that the phantom is the principal mythical figure which comes from the writer's unconsious, oscillates between dream and reality and its action knows no bounds : it can easily move from the sea to the sky, reach the universe and even the bowels of the earth or the abyss. There are plenty of phantoms in a writer's texts and this thesis demonstrate that they are beings of the imagination, which metamorphose continuously, icarnate the absence of persons or objects and transformate the poetic I into a phantom. They can also represent functions : literary, allegorical, moral and arhetypal. In conclusion, the phantom could be defined as a figure denuded of all meanings, which gets an entity in the literary texts representing a childhood trauma, an unfulfilled desire, a moral message, an archetype
Mirror Movements in Movement Disorders: A Review
Creators: name: Cox, Benjamin C.
name: Cincotta, Massimo
name: Espay, Alberto J.
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2012

description: Background: Mirror movements (MM) are involuntary movements of homologous muscles during voluntary movements of contralateral body regions. While subtle mirroring can be present in otherwise healthy adults, overt MM may be common in many movement disorders. Examining these collective findings may further our understanding of MM and help define their usefulness as a clinical sign. Methods: We sought to review English language research articles examining the presence, clinical significance, and/or pathophysiology of MM in Parkinson's disease (PD), corticobasal syndrome (CBS), essential tremor (ET), focal hand dystonia, Creutzfeldt-Jakob's disease (CJD), and Huntington's disease. When available, MM in these disorders were compared with those of healthy age-matched controls and congenital disorders such as Klippel-Feil syndrome and X-linked Kallman's syndrome. Results: Clinical presentation of MM is common in asymmetric parkinsonian disorders (early PD, CBS) and manifests differently depending on the side affected (less affected hand in PD, more affected hand in CBS, either hand in ET, and both hands in healthy adults and congenital disorders), stage of disease (early, asymmetric PD and CJD), and presence of concomitant mirror-like overflow phenomena (focal dystonia and CBS-associated alien hand). In general, uncrossed descending corticospinal projections (congenital MM) and/or abnormal activation of the motor cortex ipsilateral to the voluntary task (most acquired MM), i.e., activation of the normal crossed corticospinal pathway, are required for the generation of MM. Discussion: MM are common motor phenomena and present differently in several acquired (mostly neurodegenerative) and congenital movement disorders. Future studies on MM will enhance the clinical diagnosis of selected movement disorders and contribute to our understanding of the normal physiology of bimanual coordination.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Exploring the stability of twisted van der Waals heterostructures
Creators: name: Silva, Andrea
name: Claerbout, Victor E. P.
name: Polcar, Tomas
name: Kramer, Denis
name: Nicolini, Paolo
Publisher: name: arXiv
Year: 2020
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Chemical Physics (physics.chem-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Recent research showed that the rotational degree of freedom in stacking 2D materials yields great changes in the electronic properties. Here we focus on an often overlooked question: are twisted geometries stable and what defines their rotational energy landscape? Our simulations show how epitaxy theory breaks down in these systems and we explain the observed behaviour in terms of an interplay between flexural phonons and the interlayer coupling, governed by Moiré superlattice. Our argument applied to the well-studied MoS$_2$/Graphene system rationalize experimental results and could serve as guidance to design twistronics devices.
Hybrid Power-Law Models of Network Traffic
Creators: name: Devlin, Pat
name: Kepner, Jeremy
name: Luo, Ashley
name: Meger, Erin
Publisher: name: arXiv
Year: 2021
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Discrete Mathematics (cs.DM)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: The availability of large scale streaming network data has reinforced the ubiquity of power-law distributions in observations and enabled precision measurements of the distribution parameters. The increased accuracy of these measurements allows new underlying generative network models to be explored. The preferential attachment model is a natural starting point for these models. This work adds additional model components to account for observed phenomena in the distributions. In this model, preferential attachment is supplemented to provide a more accurate theoretical model of network traffic. Specifically, a probabilistic complex network model is proposed using preferential attachment as well as additional parameters to describe the newly observed prevalence of leaves and unattached nodes. Example distributions from this model are generated by considering random sampling of the networks created by the model in such a way that replicates the current data collection methods.
description: 8 pages, 4 figures. arXiv admin note: text overlap with arXiv:1904.04396
(Co)homology of triassociative algebras
Creators: name: Yau, Donald
Publisher: name: arXiv
Year: 2006
Subjects: subject: Rings and Algebras (math.RA)
subject: Algebraic Topology (math.AT)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 17D99

description: We study homology and cohomology of triassociative algebras with non-trivial coefficients.
description: 22 pages. To appear in Int. J. Math. Math. Sci
Tríptico informativo sobre Poliquistosis Renal Autosómica Dominante (PQRAD) y cómo se puede prevenir su transmisión
Creators: name: Esteban-de-la-Rosa, Rafael-José
name: Bravo-Soto, Juan-Antonio
name: García-Valverde, María
Publisher: name: Zenodo
Year: 2014

description: El presente tríptico informativo sobre poliquistosis renal autosómica dominante (PQRAD) explica de forma sencilla en qué consiste la enfermedad, cómo se manifiesta, cómo se transmite a la descendencia así como las técnicas reproductivas mediante las que se puede evitar su transmisión, como el test genético preimplantacional (TGP) y la donación de gametos, y por tanto que puedan nacer hijos sanos libres de la enfermedad de padres afectos.
Quantifying The Drivers and Impacts of Natural Disturbance Events – The 2013 Colorado Floods
Creators: name: Zimbler-DeLorenzo, Heather
Publisher: name: QUBES Educational Resources
Year: 2019

description: This lesson focuses on ways that scientists identify and use data to understand ecological disturbance events using data from five public datasets. The main lesson focused on interpretation of figures, while optional coding extensions teach R skills.
Συγκριτική μελέτη ιστικής κατανομής των αντιμικροβιακών ουσιών, λινεζολίδη, λεβοφλοξασίνη, μοξιφλοξασίνη στα οστά και τις αρθρώσεις
Creators: name: Μεταλλίδης, Συμεών Α.
Publisher: name: Aristotle University of Thessaloniki
Year: 2006
Subjects: Λινεζολίδη
Λεβοφλοξασίνη
Μοξιφλοξασίνη
Linezolid
Levofloxacin
Moxifloxacin

description: Οι λοιμώξεις οστών και αρθρώσεων έχουν παρόμοιο μικροβιολογικό φάσμα, όπου κυριαρχούν τα gram(+) μικρόβια και ακολουθούν τα gram(-). Απαιτούν παρατεταμένη θεραπεία και έχουν υψηλό ποσοστό θνητότητας και νοσηρότητας. Σκοπός της μελέτης ήταν να εξεταστούν οι συγκεντρώσεις των αντιμικροβιακών λινεζολίδης, λεβοφλοξασίνης και μοξιφλοξασίνης στα οστά και αρθρικο υγρό, για να προσδιοριστούν τα ποσοστά διείσδυσης και οι θεραπευτικοί δείκτες. Για τον προσδιορισμό των συγκεντρώσεων των υπό εξέταση αντιβιοτικών χρησιμοποιήθηκε η μέθοδος της υγρής χρηματογραφίας υψηλής πίεσης. Στη μελέτη συμπεριλήφθησαν 96 ασθενείς που υποβλήθηκαν σε ορθοπεδικές επεμβάσεις. Τα ποσοστά διείσδυσης στα οστά για την λινεζολίδη ήταν 31%-48,5%, για την λεβοφλοξασίνη 36,1%-53,8% και για την μοξιφλοξασίνη 34,2%-57,5%. Τα αντίστοιχα ποσοστά στο αρθρικό υγρό ήταν 60,9%, 62,5% και 74,6%. Η λινεζολίδη δεν μπόρεσε να διατηρήσει τον χρόνο πάνω από την MIC για περισσότερι από 40% του δασολογικού διαστήματος και δεν πρέπει να χρησιμοποιείται σε οστεομυελίτιδες. Η μυξιφλοξασίνη πρέπει να προτιμάται σε λοιμώξεις από σταφυλόκοκκο γιατί επιτυγχάνει υψηλούς θεραπευτικούς δείκτες. Αντίθετα στα gram(-) πρέπει να προτιμάται η λεβοφλοξασίνη με βάση φαρμακοκινητικούς-φαρμακοδυναμικούς παράγοντες αποτελεί την ειδοποιό διαφορά στην κλινική επιτυχία
description: Bone and joint infections have common microbiologic causes, especially gram(+) followed by gram(-). They are associated with great mortality and morbility and usually need prolonged therapy. The aim of this study was to measure the concentrations of linezolid, levofloxacin and moxifloxacin into bone and synovial fluid and to calculate the penetration and therapeutic index. 96 patients were included in the study, which all underwent orthopedic surgery. The penetration index into bone was 31,8%-48,5% for linezolid, 36,1%-53,8% for levofloxacin and 34,2%-57,5% for moxifloxacin. The penetration index into synovial fluid was 60,9%, 62,5% and 74,6% respectively. Linezolid did not achieve the goal of T>MIC for more than 40% of the interval dose and therefore should not be used for the treatment of osteomyelitis. Moxifloxacin must be preferred in infection caused by Staph. aureus due to its high therapeutic index. On the other hand levofloxacin must be prefered for gram(-) infections based on the therapeutic index. When treating difficult infections such us osteomyelitis the choise of antiobiotics based on PK/PD might be the difference in clinical success
DefocusTracker: A modular toolbox for defocusing-based, single-camera, 3D particle tracking
Creators: name: Barnkob, Rune
name: Rossi, Massimiliano
Publisher: name: arXiv
Year: 2021
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The need for single-camera 3D particle tracking methods is growing, among others, due to the increasing focus in biomedical research often relying on single-plane microscopy imaging. Defocusing-based methods are ideal for a wide-spread use as they rely on basic microscopy imaging rather than requiring additional non-standard optics. However, a wide-spread use has been limited by the lack of accessible and easy-to-use software. DefocusTracker is an open-source toolbox based on the universal principles of General Defocusing Particle Tracking (GDPT) relying solely on a reference look-up table and image recognition to connect a particle's image and its respective out-of-plane depth coordinate. The toolbox is built in a modular fashion, allowing for easy addition of new image recognition methods, while maintaining the same workflow and external user interface. DefocusTracker is implemented in MATLAB, while a parallel implementation in Python is in the preparation.
description: 11 pages, 3 figures, submitted for Journal of Open Research Software (JORS)
Cognitive Features of Essential Tremor: A Review of the Clinical Aspects and Possible Mechanistic Underpinnings
Creators: name: Bermejo-Pareja, Félix
name: Puertas-Martín, Verónica
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2012

description: Background: The classical concept of essential tremor (ET) as a monosymptomatic tremorogenic disorder has been questioned in the last decade as new evidence has been described. Clinical, neuroimaging, and pathological studies have described a probable structural basis (mainly in cerebellum) and evidence that ET is associated with subtle clinical cerebellar deficits and several non-motor clinical manifestations, such as cognitive and mood disorders. Case Report: We performed literature searches in Medline, ISI Web of Knowledge, and PsycInfo databases. The aim of this review is to describe cognitive deficits associated with ET. First, we present a brief history of ET cognitive disorders presented. Second, we describe several clinical cross-sectional series demonstrating that ET is associated with mild cognitive deficits of attention, executive functions, several types of memory (working memory, immediate, short term, delayed, and possibly others) and, mood disorders (depression). Discussion: Recent neuroimaging studies favor a cerebellar basis for these cognitive deficits. Population-based surveys confirm that mild cognitive dysfunction is not limited to severe ET cases, the entire ET group, including mild and undiagnosed cases, can be affected. Cohort studies indicated that ET cognitive deficits could be progressive and that ET patients had an increased risk of dementia. The mood and cognitive deficits in ET are in agreement with cognitive affective cerebellar syndrome described in patients with cerebellar disorders. New evidence, mainly from functional (neuroimaging) and prospective clinical studies would further bolster recent descriptions of ET clinical manifestations.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Enciclopedia Calvino. Geografia (Roma, 10 maggio 2023)
Creators: name: Bilardi, Carlotta
Publisher: name: Semestrale di studi e ricerche di geografia
Year: 2023

description: In occasione del Centenario della nascita di Italo Calvino, il Laboratorio Calvino (Sapienza Università di Roma, Università degli studi di Milano e di Milano Bicocca, University of Oxford), diretto da Laura Di Nicola (“Sapienza” Università di Roma) ha organizzato l’iniziativa, patrocinata dall’AIIG, “Enciclopedia Calvino. Incontri e seminari multidisciplinari per il centenario” con una serie di seminari nel periodo marzo - giugno 2023 in cui si affronta l’opera di Calvino nella rete di connessioni con i saperi su cui lo scrittore basa le possibilità di leggere e raccontare il mondo.
description: Semestrale di studi e ricerche di geografia, N. 1 (2023): Critical toponimy: practices of (re)naming and the power to trasnform time into space
Hermitian and quaternionic Hermitian structures on tangent bundles
Creators: name: Albuquerque, Rui
Publisher: name: arXiv
Year: 2007
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53C15, 53C26, 53C55

description: We review the theory of quaternionic Kahler and hyperkahler structures. Then we consider the tangent bundle of a Riemannian manifold M with a metric connection D (with torsion) and with its well estabilished canonical complex structure. With an extra almost Hermitian structure on M it is possible to find a quaternionic Hermitian structure on TM, which is quaternionic Kahler if, and only if, D is flat and torsion free. We also review the symplectic nature of TM. Finally a proper S^3-bundle of complex structures is introduced, expanding to TM the well known twistor bundle of M.
description: 18 pages
Διερεύνηση του ρόλου των γλυκοζαμινογλυκάνων στην παθοφυσιολογία της καλοήθους υπερπλασίας του προστάτη πριν και μετά τη φαρμακευτική αγωγή
Creators: name: Καλινδέρης, Νικόλαος Α.
Publisher: name: Aristotle University of Thessaloniki
Year: 2006
Subjects: Μεταλλοπρωτάσσες
Θειϊκή Χονδροϊτίνη/Δερματάνη
Τεραζοσίνη
Metalloproteases
Chondroitin/Dermatan/Sulfate
Terazosin

description: Ο σκοπός της παρούσας μελέτης ήταν ο χαρακτηρισμός των GAGs οι οποίες υπάρχουν στο φυσιολογικό ανθρώπινο προστάτη και μελέτη τυχόν μεταβολών στη συγκέντρωση αυτών σε ΚΥΠ. Επιπλέον σε μελέτες σε πειραματικά μοντέλα ερευνήθηκε η επίδραση της τεραζοσίνης, -ενός αποκλειστή των α-υποδοχέων με γνωστή επαγωγική δράση στο φαινόμενο της απόπτωσης στον προστάτη-, στη συγκέντρωση των GAGs, στη δραστηριότητα των MMP-2 και MMP-9 και στην περιεκτηκότητα των ιστικών αναστολέων των MMP (TIMP), δεδομένου ότι τόσο οι GAGs όσο και οι MMPs επηρεάζουν την απόπτωση
description: The aim of the present study was to characterize GAGs that are present in the normal human prostate and identify possible quantitative changes in BPH; furthermore in animal studies, we investigated the effects of terazosin - an alpha-blocker antagonist which has shown to interfere with the apoptotic process of the prostate - on the content of GAGs, the activity of MMP-2 and MMP-9 and on the content of tissue inhibitors of MMP (TIMP), as it is well known that both GAGs and MMPs do affect apoptosis
HI Absorption in High-Frequency Peaker Galaxies
Creators: name: Orienti, M.
name: Morganti, R.
name: Dallacasa, D.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: WSRT observations have been used to investigate the presence of neutral hydrogen in extremely young radio galaxies. These objects were selected from a sample of High-Frequency Peakers (HFPs). We detect 2 of the 6 observed galaxies confirming previous detection of HI in these objects. In the case of OQ 208 - for which discrepant results were available - we confirm the presence of a broad (~ 1800 km/s), blue-shifted and shallow HI absorption. No significant changes in the HI profile have been found between the two epochs of the observations. The intriguing result is that the derived HI column densities and upper limits obtained for the most compact sources, do not follow the inverse correlation between the column density and the linear size found for CSS/GPS sources. This can be explained - assuming the gas is already in a torus/disk structure - by a combination of the orientation and the extreme compactness of the sources. In this scenario, our line of sight to the source would intersect the torus in its inner region with low optical depth due to high spin and kinetic temperatures. There is no evidence, with the exception of OQ 208, of unsettled, high column density gas still enshrouding the young radio sources. This can be due to the low filling factor of such a medium.
description: 7 pages, 5 figures; accepted for pubblication in A&A
Reversibility of Tardive Dyskinesia Syndrome
Creators: name: Vinuela, Angel
name: Kang, Un Jung
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2014

description: This Editorial was written in response to: Zutshi D, Cloud LJ, Factor SA. Tardive Syndromes are Rarely Reversible after Discontinuing Dopamine Receptor Blocking Agents: Experience from a University-based Movement Disorder Clinic. Tremor Other Hyperkinet Mov. 2014; 4. doi:10.7916/D8MS3R8C Erratum published July 27, 2015
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Key Issues in Essential Tremor Genetics Research: Where Are We Now and How Can We Move Forward?
Creators: name: Testa, Claudia M
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2013

description: Genetics research is an avenue towards understanding essential tremor (ET). Advances have been made in genetic linkage and association: there are three reported ET susceptibility loci, and mixed but growing data on risk associations. However, causal mutations have not been forthcoming. This disappointing lack of progress has opened productive discussions on challenges in ET genetics research, including fundamental assumptions in the field. This article reviews the ET genetics literature, results to date, the open questions in ET genetics and the current challenges in addressing them. Several inherent ET features complicate genetic linkage and association studies: high potential phenocopy rates, inaccurate tremor self-reporting, and ET misdiagnoses are examples. Increasing use of direct exam data for subjects, family members and controls is one current response. Smaller moves towards expanding ET phenotype research concepts into non-tremor features, clinically disputed ET subsets, and testing phenotype features instead of clinical diagnosis against genetic data are gradually occurring. The field has already moved to considering complex trait mechanisms requiring detection of combinations of rare genetic variants. Hypotheses may move further to consider novel mechanisms of inheritance, such as epigenetic. It is an exciting time in ET genetics as investigators start moving past assumptions underlying both phenotype and genetics experimental contributions, overcoming challenges to collaboration, and engaging the ET community. Multicenter collaborative efforts comprising rich longitudinal prospective phenotype data and neuropathologic analysis combined with the latest in genetics experimental design and technology will be the next wave in the field.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Spectral action on SU_q(2)
Creators: name: Iochum, B.
name: Levy, C.
name: Sitarz, A.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The spectral action on the equivariant real spectral triple over \A(SU_q(2)) is computed explicitly. Properties of the differential calculus arising from the Dirac operator are studied and the results are compared to the commutative case of the sphere S^3.
description: 47 pages
The phase symmetry of general relativity
Creators: name: Samokhvalov, Serhii
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: It is shown that the general relativity has a one-parameter compact symmetry and this symmetry is analogous to the phase symmetry of quantum mechanics
description: 10 pages
Mirror Movements in Essential Tremor: Prevalence and Relationship to Mini-Mental Status Test Scores
Creators: name: Louis, Elan D.
name: Gillman, Arthur
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2012

description: Background: Mirror movements (MM) are mirror reversals of contralateral, voluntary alternating or repetitive limb movements. MM have been described in age-related neurological diseases, including essential tremor (ET). MM could represent a motor release sign. Cognitive dysfunction (especially executive dysfunction) and dementia have also been reported among ET patients. It is conceivable that MM and cognitive dysfunction in ET arise from the same underlying anatomical or physiological substrate. Hence, the underlying clinical question is whether MM are a simple and easily elicited motor marker for incipient cognitive change or dementia in ET? Identifying such a marker would have value to clinicians, and we are unaware of prior studies that have assessed this issue. Methods: The Folstein Mini-Mental State Exam (FMMSE) and the Modified Mini-Mental Status Examination (mMMSE) were administered to 148 ET cases enrolled in a cross-sectional clinical study. Results: MM were present in 115 out of 148 (77.7%) ET cases. In analyses that considered age, there were no differences in FMMSE or mMMSE scores between participants with vs. without MMs (all p values >0.05). Discussion: These data suggest that MM, while present in a considerable number of ET cases, would not be a useful motor marker for incipient cognitive change in ET cases.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Characterization of a mutant strain of murine cytomegalovirus which fails to grow in salivary glands
Creators: name: Boname, Jessica Miriam
Publisher: name: University of British Columbia
Year: 2011

description: An understanding of the mechanisms of pathogenesis of cytomegaloviruses is essential for future work towards control and prevention of cytomegalovirus disease. Towards this end, a comparison of the Smith, Vancouver and K-181 strains of murine cytomegalovirus (MCMV), which differ in virulence, revealed differences in growth characteristics in vivo and in vitro. The Vancouver strain of MCMV grows to a limited extent in the spleen while it fails to grow in the salivary glands of inoculated mice (salivary gland growth mutant, Sgg⁻). This mutation probably arose during multiple in vitro passage of the parental Smith strain. In vitro, the Vancouver strain replicated more quickly and produced a greater yield of virus per cycle which resulted in a larger plaque size relative to the Smith or K-181 strains. The Vancouver strain has a 9.4 kb deletion, which spans the XbaI I/L junction of the parental Smith strain (0.960 to 0.995 map units), and a 0.9 kb insertion which maps to the EcoRI K fragment (0.37 to 0.47 map units). Recombinant MCMV was generated by co-transfection of cells with whole Vancouver strain DNA and cloned fragments of wild-type DNA. Three independent Sgg⁺ recombinant viruses were selected by passage of the co-transfected virus through mouse salivary glands. The three recombinants had recovered the DNA deletion, while they maintained the insertion associated with the Vancouver strain. Thus, the genotypic location of the defect responsible for the Sgg⁻ phenotype of the Vancouver strain of MCMV maps to 0.960 to 0.995 map units of the Smith virus genome. In addition, the restoration of this region of the genome correlated with the detection in the recombinants of a 42 kDa protein present during E and L times post infection in Smith- and K-181-infected cells, but not in Vancouver strain-infected cells. The K-181 strain was associated with higher salivary gland titres and a low LD₅₀ titre consistent with the increased virulence of this strain compared with the Smith strain. Differences in the K-181 restriction endonuclease pattern relative to the Smith strain were mapped, and were mainly confined to 0.0 to 0.06 map units of the genome without any large insertions or deletions detected. Minor differences in the proteins of the Smith and K-181 strains at early and late times post infection were also detected. The identification of a gene involved in the salivary gland tropism of MCMV and the characterization of differences between the Smith and K-181 strains of MCMV should increase our understanding of the virulence mechanisms of cytomegaloviruses.
Metabolic Hyperactivity of the Medial Posterior Parietal Lobes in Psychogenic Tremor
Creators: name: Hedera, Peter
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2012

description: Background: The pathophysiology of psychogenic movement disorders, including psychogenic tremor (PT), is only emerging. Case Report: This is a single case report of a patient who met diagnostic criteria for PT. He underwent positron emission tomography (PET) of brain with 18F-deoxyglucose at resting state. His PET study showed symmetrically increased 18F-deoxyglucose uptake in both posterior medial parietal lobes. There was no corresponding abnormality on structural imaging. Discussion: Hypermetabolism of the medial aspects of posterior parietal lobes bilaterally may reflect abnormal activity of sensory integration that is important in the pathogenesis of PT. This further supports the idea that non-organic movement disorders may be associated with detectable functional brain abnormalities.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Weight Enumerators and Cardinalities for Number-Theoretic Codes
Creators: name: Nozaki, Takayuki
Publisher: name: arXiv
Year: 2020
Subjects: subject: Information Theory (cs.IT)
subject: Combinatorics (math.CO)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: The number-theoretic codes are a class of codes defined by single or multiple congruences. These codes are mainly used for correcting insertion and deletion errors, and for correcting asymmetric errors. This paper presents a formula for a generalization of the complete weight enumerator for the number-theoretic codes. This formula allows us to derive the weight enumerators and cardinalities for the number-theoretic codes. As a special case, this paper provides the Hamming weight enumerators and cardinalities of the non-binary Tenengolts' codes, correcting single insertion or deletion. Moreover, we show that the formula deduces the MacWilliams identity for the linear codes over the ring of integers modulo $r$.
description: 9 pages, accepted to IEEE Transactions on Information Theory
Ανάπτυξη και εφαρμογές σύγχρονων βιοδιαγνωστικών μεθόδων στην ανάλυση της γενετικής σύστασης και της έκφρασης των γονιδίων στα φυτά
Creators: name: Ακριτίδης, Πασχάλης Γ.
Publisher: name: Aristotle University of Thessaloniki
Year: 2006
Subjects: Ανιχνευτής
Μικροσυστοιχίες
Μικροδορυφόροι
Detection
Microarray
Microsatelites

description: Πραγματοποιήθηκε απομόνωση και χαρακτηρισμός της περιοχής ένωσης ανάμεσα στο διαγονίδιο και γενωμικό DNA του γενετικά τροποποιημένου βάμβακος Roundup Readx 1445. Ως υλικό για πειραματικό χρησιμοποιήθηκε άγνωστο δείγμα που βρέθηκε θετικό για 355 ειδικό εκκινητή. Εξαιτίας του γεγονότος ότι η ενσωμάτωση του διαγονιδίου στο γονιδίωμα του φυτού γίνεται τυχαία, η μέθοδος αποτελεί εξιεδικευμένο τρόπο ανίχνευσης ΓΤΟ. Σε μια προσπάθεια μαζικής ανίχνευσης γενετικά τροποποιημένων στοιχείων, πραγματοποιήθηκε εκτύπωση 8 αλληλουχιών(ευρέως χρησιμοποιηούμενων στην παρασκευή ΓΤΟ), σε επιφάνεια μικροσυστοιχιών. Ακολούθησε επιτυχής υβριδισμός με ιχνηλάτη σύλληψης συμπληρωματικό για 3 από τις ακολουθίες. Στόχο της εργασίας αποτέλεσε η ανίχνευση επαγωγής των γονιδίων Cat, Sod, Apx σε φυτά M. truncatula μετά από συνθήκες καταπόνησης. Μεταχείριση με σίδηρο οδήγησε στην παραγωγή .ΟΗ μέσω της αντίδρασης Fenton και κατ'επέκταση στην επαγωγή των γονιδίων Cat και Sod. Ακολούθως ερευνήθηκε ο ρόλος των μοριακών σημάτων στην επαγωγή των γονιδίων και βρεθηκε ότι το ΝΟ ευθύνεται πιθανά για την επαγωγή της Cat στα φύλλα μετά από μεταχείριση στις ρίζες. Επίσης το ΝΟ προκάλεσε επαγωγή των γονιδίων uorAPX και AOX, μετά από τοπική μεταχείριση και υδροπονικά. Σε ανάλυση παραλακτικότητας με μικροδορυφόρους σε 31 άτομα M. trancatula και M. littorialis, με χρήση 9 ζευγών ειδικών εκκινητών ανιχνεύθηκαν 42 αλληλόμορφα. Παρατηρήθηκε ότι δεν υπάρχει συσχετισμός ανάμεσα στους γενότυπους και την γεωγραφική κατανομή των οικότοπων
description: In this report is described the isolation and characterisation of the junction between insert DNA and plant DNA in the transgenic Round up ready cotton 1445. Since i started from and unknown material that has been scanned positive for 355 promoter, i emphasize the possibility of developing detection methods for specific events by not having direct access in known genetic modified material. In an effort to develop a parallel method of detection of genetically modified species, 8 sequences commonly used in 6m plants were printed microarray shole and hybridised with a relevant probe. The hybridisation was succesful indicating the reliability of the method. In order to determine the significance and the role of cats and Sods in M. truncatula stress adaptation, i examined their response to different types of induced stress. Activity levels were measured in response to oxidative stress induced by iron over load which loads to formation of .OH through Fenton reaction. Our data revealed that iron overload caused the highest induction of Cat and Sod enzymatic activities in M. truncatula
Cavitation controls droplet sizes in elastic media
Creators: name: Vidal-Henriquez, Estefania
name: Zwicker, David
Publisher: name: arXiv
Year: 2021
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: Biological cells use droplets to separate components and spatially control their interior. Experiments demonstrate that the complex, crowded cellular environment affects the droplet arrangement and their sizes. To understand this behavior, we here construct a theoretical description of droplets growing in an elastic matrix, which is motivated by experiments in synthetic systems where monodisperse emulsions form during a temperature decrease. We show that large droplets only form when they break the surrounding matrix in a cavitation event. The energy barrier associated with cavitation stabilizes small droplets on the order of the mesh size and diminishes the stochastic effects of nucleation. Consequently, the cavitated droplets have similar sizes and highly correlated positions. In particular, we predict the density of cavitated droplets, which increases with faster cooling, as in the experiments. Our model also suggests how adjusting the cooling protocol and the density of nucleation sites affects the droplet size distribution. In summary, our theory explains how elastic matrices affect droplets in the synthetic system and it provides a framework for understanding the biological case.
Strong clustering of underdense regions and the environmental dependence of clustering from Gaussian initial conditions
Creators: name: Abbas, Ummi
name: Sheth, Ravi K.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We discuss two slightly counter-intuitive findings about the environmental dependence of clustering in the Sloan Digital Sky Survey. First, we find that the relation between clustering strength and density is not monotonic: galaxies in the densest regions are more strongly clustered than are galaxies in regions of moderate overdensity; galaxies in moderate overdensities are more strongly clustered than are those in moderate underdensities; but galaxies in moderate underdensities are less clustered than galaxies in the least dense regions. We argue that this is natural if clustering evolved gravitationally from a Gaussian field, since the highest peaks and lowest troughs in Gaussian fields are similarly clustered. The precise non-monotonic dependence of galaxy clustering on density is very well reproduced in a mock catalog which is based on a halo-model decomposition of galaxy clustering. Second, the distribution of galaxy counts in our sample is rather well described by a Poisson cluster model. We show that, despite their Poisson nature, correlations with environment are expected in such models. More remarkably, the expected trends are very like those in standard models of halo bias, despite the fact that correlations with environment in these models arise purely from the fact that dense regions are dense because they happen to host more massive halos. This is in contrast to the usual analysis which assumes that it is the large scale environment which determines the halo mass function. [Abridged]
description: 10 pages, 5 figures, accepted for publication in MNRAS
Sanaungulus ruicheni Fanti 2018, n. comb.
Creators: name: Fanti, Fabrizio
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cantharidae
Sanaungulus
Sanaungulus ruicheni

description: Sanaungulus ruicheni (Hsiao & Huang, 2018) n. comb.
(Cantharidae Cantharinae Cantharini)
 Ornatomalthinus ruicheni Hsiao & Huang, 2018 (Cantharidae Silinae Silini)
 The species delimitation is often very problematic when limited information on different semaphoronts is available in highly sexually dimorphic groups. This is also reflected in the taxonomy of the Cantharidae, even at the subfamily or tribe level. One example is the genus Tytthonyx LeConte, 1851 which is placed in the subfamily Silinae as incertae sedis showing intermediate characters with the subfamily Malthininae Kiesenwetter, 1852 (Brancucci, 1980). Ornatomalthinus and Sanaungulus show a remarkably different head shape. The possibility that it is due to feed on nectar and pollen (Hsiao & Huang, 2018) is currently unsupported by clear evidence since genera and species (even in soldier beetles) feeding on pollen commonly tend to have a stretched rostrum not a modified posterior part of the cranium. Moreover, soldier beetles tend to be predators and are only occasional nectarivorous, the latter strategy present due to the development of the angiosperms in the Cretaceous. Therefore, the difference of the shape of the head, in contrast to what Hsiao & Huang (2018) claimed, confirm that the two genera represent independent lineages deserving the genus rank.
 Ornatomalthinus ruicheni Hsiao & Huang, 2018 is transferred to Sanaungulus. As a result, the fossil genus Ornatomalthinus remains monotypic with the only type species O. elvirae Poinar & Fanti, 2016 and three species are now placed in the fossil genus Sanaungulus: S. curtipennis Fanti, Damgaard & Ellenberger, 2018, S. ghitaenoerbyae Fanti, Damgaard & Ellenberger, 2018 (Poinar & Fanti, 2016; Fanti et al., 2018) and Sanaungulus ruicheni. The genera Ornatomalthinus and Sanaungulus belong to the subfamily Cantharinae Imhoff, 1856 and not to the subfamily Silinae Mulsant, 1862.
description: Published as part of Fanti, Fabrizio, 2018, Sanaungulus ruicheni (Hsiao & Huang, 2018) n. comb. with the differential diagnosis of genera Sanaungulus Fanti, Damgaard & Ellenberger, 2018 and Ornatomalthinus Poinar & Fanti, 2016, pp. 449-450 in Zootaxa 4514 (3) on pages 449-450, DOI: 10.11646/zootaxa.4514.3.11, http://zenodo.org/record/2608838
Constrained bounds on measures of entanglement
Creators: name: Datta, Animesh
name: Flammia, Steven T.
name: Shaji, Anil
name: Caves, Carlton M.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Entanglement measures constructed from two positive, but not completely positive maps on density operators are used as constraints in placing bounds on the entanglement of formation, the tangle, and the concurrence of 4 x N mixed states. The maps are the partial transpose map and the $Φ$-map introduced by Breuer [H.-P. Breuer, Phys. Rev. Lett. 97, 080501 (2006)]. The norm-based entanglement measures constructed from these two maps, called negativity and $Φ$-negativity, respectively, lead to two sets of bounds on the entanglement of formation, the tangle, and the concurrence. We compare these bounds and identify the sets of 4 x N density operators for which the bounds from one constraint are better than the bounds from the other. In the process, we present a new derivation of the already known bound on the concurrence based on the negativity. We compute new bounds on the three measures of entanglement using both the constraints simultaneously. We demonstrate how such doubly constrained bounds can be constructed. We discuss extensions of our results to bipartite states of higher dimensions and with more than two constraints.
description: 28 pages, 12 figures. v2 simplified and generalized derivation of main results; errors corrected
LINGO-1 and Neurodegeneration: Pathophysiologic Clues for Essential Tremor?
Creators: name: Zhi-Dong, Zhou
name: Sathiyamoorthy, Sushmitha
name: Tan, Eng-King
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2012

description: Essential tremor (ET), one of the most common adult-onset movement disorders, has been associated with cerebellar Purkinje cell degeneration and formation of brainstem Lewy bodies. Recent findings suggest that genetic variants of the leucine-rich repeat and Ig domain containing 1 (LINGO-1) gene could be risk factors for ET. The LINGO-1 protein contains both leucine-rich repeat (LRR) and immunoglobulin (Ig)-like domains in its extracellular region, as well as a transmembrane domain and a short cytoplasmic tail. LINGO-1 can form a ternary complex with Nogo-66 receptor (NgR1) and p75. Binding of LINGO-1 with NgR1 can activate the NgR1 signaling pathway, leading to inhibition of oligodendrocyte differentiation and myelination in the central nervous system. LINGO-1 has also been found to bind with epidermal growth factor receptor (EGFR) and induce downregulation of the activity of EGFR–PI3K–Akt signaling, which might decrease Purkinje cell survival. Therefore, it is possible that genetic variants of LINGO-1, either alone or in combination with other genetic or environmental factors, act to increase LINGO-1 expression levels in Purkinje cells and confer a risk to Purkinje cell survival in the cerebellum. Here, we provide a concise summary of the link between LINGO-1 and neurodegeneration and discuss various hypotheses as to how this could be potentially relevant to ET pathogenesis.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Disentangling Dimension Six Operators through Di-Higgs Boson Production
Creators: name: Pierce, Aaron
name: Thaler, Jesse
name: Wang, Lian-Tao
Publisher: name: arXiv
Year: 2006
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: New physics near the TeV scale can generate dimension-six operators that modify the production rate and branching ratios of the Higgs boson. Here, we show how Higgs boson pair production can yield complementary information on dimension-six operators involving the gluon field strength. For example, the invariant mass distribution of the Higgs boson pair can show the extent to which the masses of exotic TeV-scale quarks come from electroweak symmetry breaking. We discuss both the current Tevatron bounds on these operators and the most promising LHC measurement channels for two different Higgs masses: 120 GeV and 180 GeV. We argue that the operators considered in this paper are the ones most likely to yield interesting Higgs pair physics at the LHC.
description: 20 pages, 7 figures; v2: to match JHEP version
Narrowing of d bands of FeCo layers intercalated under graphene
Creators: name: Pacilè, Daniela
name: Cardoso, Claudia
name: Avvisati, Giulia
name: Vobornik, Ivana
name: Mariani, Carlo
name: Leon, Dario A.
name: Bonfà, Pietro
name: Varsano, Daniele
name: Ferretti, Andrea
name: Betti, Maria Grazia
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report on the electronic properties of an artificial system obtained by the intercalation of equiatomic FeCo layers under graphene grown on Ir(111). Upon intercalation, the FeCo film grows epitaxially on Ir(111), resulting in a lattice-mismatched system. By performing Density Functional Theory calculations, we show that the intercalated FeCo layer leads to a pronounced corrugation of the graphene film. At the same time, the FeCo intercalated layers induce a clear transition from a nearly undisturbed to a strongly hybridized graphene π-band, as measured by angle-resolved photoemission spectroscopy. A comparison of experimental results with the computed band structure and the projected density of states unveils a spin-selective hybridization between the π band of graphene and FeCo-3d states. Our results demonstrate that the reduced dimensionality, as well as the hybridization within the FeCo layers, induce a narrowing and a clear splitting of Fe 3d-up and Fe 3d-down spin bands of the confined FeCo layers with respect to bulk Fe and Co.
description: 5 pages, 4 figures