cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The DEWCAD Project: Pushing Back the Doubly Exponential Wall of Cylindrical Algebraic Decomposition
Creators: name: Bradford, R.
name: Davenport, J. H.
name: England, M.
name: Sadeghimanesh, A.
name: Uncu, A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Symbolic Computation (cs.SC)
subject: FOS: Computer and information sciences
subject: I.1.2; I.1.4; G.4; J.3; J.4
subject: 68W30, 03C10

description: This abstract seeks to introduce the ISSAC community to the DEWCAD project, which is based at Coventry University and the University of Bath, in the United Kingdom. The project seeks to push back the Doubly Exponential Wall of Cylindrical Algebraic Decomposition, through the integration of SAT/SMT technology, the extension of Lazard projection theory, and the development of new algorithms based on CAD technology but without producing CADs themselves. The project also seeks to develop applications of CAD and will focus on applications in the domains of economics and bio-network analysis.
description: 5 pages. Accepted as short communication at ISSAC 2021
Virtual Reality Feedback Cues for Improvement of Gait in Patients with Parkinson's Disease
Creators: name: Badarny, Samih
name: Aharon-Peretz, Judith
name: Susel, Zvi
name: Habib, George
name: Baram, Yoram
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2014

description: Background: Our aim was to study the effects of visual feedback cues, responding dynamically to patient's self‐motion and provided through a portable see‐through virtual reality apparatus, on the walking abilities of patients with Parkinson's disease. Methods: Twenty patients participated. On‐line and residual effects on walking speed and stride length were measured. Results Attaching the visual feedback device to the patient with the display turned off showed a negligible effect of about 2%. With the display turned on, 56% of the patients improved either their walking speed, or their stride length, or both, by over 20%. After device removal, and waiting for 15 minutes, the patients were instructed to walk again: 68% of the patients showed over 20% improvement in either walking speed or stride length or both. One week after participating in the first test, 36% of the patients showed over 20% improvement in baseline performance with respect to the previous test. Some of the patients reported that they still walked on the tiles in their minds. Discussion: Improvements in walking abilities were measured in patients with Parkinson's disease using virtual reality visual feedback cues. Residual effects suggest the examination of this approach in a comprehensive therapy program.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Analysis of an in-service rupture of the Inner First Wall of Tore Supra
Creators: name: Mitteau, R
name: Chappuis, P
name: Martin, G
name: Rosanvallon, S
Publisher: name: arXiv
Year: 2021
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The last experimental campaign of Tore Supra was also the last one with a set of plasma facing components mainly dating from the assembly of the machine in 1988. This campaign was interrupted a few days ahead of schedule because of the rupture of one coolant tube of the Inner First Wall (IFW). The rupture was observed by an abrupt increase of the pressure in the vessel. It was caused by a water leak which occurred two seconds after the end of the lower hybrid heating pulse during the current ramp-down. Investigations show that the accident is not related to the operation of the machine or a weaker element but rather to a localised heat flux exceeding the heat removal capability of the IFW.
Η έκφραση των υποδοχέων της τάξης HER στον καρκίνο του μαστού και βιολογική συμπεριφορά των καρκινικών κυττάρων
Creators: name: Καλέμη, Θεοδώρα
Publisher: name: Aristotle University of Thessaloniki
Year: 2007
Subjects: Υποδοχείς HER1-4
Πρωτεϊνες p21(WAF1), p27(KiP1)
Receptors HER1-4
p21(waf1), p27(waf1) proteins

description: Σκοπός της παρούσας διατριβής ήταν η διαφορική έκφραση σε επίπεδο mRNA των τεσσάρων υποδοχέων HER στον καρκίνο του μαστού καθώς και σε παρακείμενο "φυσιολογικό" ιστό. Μελετήθηκε η έκφραση των υποδοχέων ΗΕΡ1-4 σε 67 πρωτοπαθείς καρκίνους μαστού καθώς και σε παρακείμενο φυσιολογικό ιστό RT-PCR. Ακολούθησε μελέτη των οδών μεταγωγής σήματος που ενεργοποιούν οι HER και της έκφρασης των μετέπειτα σημάτων(πρωτεϊνες p21(waf1) και p27(kip1) με ανοσοαποτύπωση. Διαπιστώθηκε θετική συσχέτιση μεταξύ των υποδοχέων HER3 και HER4. Σε σύγκριση με το φυσιολογικό ιστό, όλοι οι υποδοχείς υπερεκφράζονταν στον καρκίνο του μαστού και ιδιαίτερα ο HER3. Διαπιστώθηκε αρνητική συσχέτιση του HER4 με το βαθμό κακοήθειας(HPG). Τα αποτελέσματα της ανοσοαποτύπωσης αποκαλύπτουν πολύ υψηλότερα ποσοστά έκφρασης της πρωτεϊνης p21Δ(κολωβωμένη μορφή της p21) σε σχέση με το "φυσιολογικό" μαστό. Επιπλέον οι HER-2 θετικοί όγκοι ενεργοποιούν επιλεκτικά την οδό της MARK. Στην προσπάθεια κατανόησης της παρέμβασης στις οδούς που ενεργοποιούν οι HER μελετήθηκε η επίδραση των αυξητικών παραγόντων EGF και HRG και του μονοκλωνικού αντισώματος trasturumab σε in vitro κυτταρικά πρότυπα. Τα αποτελέσματα φανερώνουν την πολυπλοκότητα της έκφρασης και της ενεργοποίησης των υποδοχέων HER στον καρκίνο του μαστού. Από τα ευρήματά μας προκύπτει επίσης ότι οι οδοί μεταγωγής σήματος μέσω των HER μπορεί να ενεργοποιούνται με διαφορετικούς μηχανισμούς οι οποίοι παράλληλα, θα πρέπει να στοχεύονται ταυτόχτονα με τους HER
description: In this thesis we determine the differential mRNA expression pattern of HER1-4 in 67 unselected human primary breast cancers and in normal breast tissue using RT-PCR. We examine also the signal transduction pathaway induced by HER receptors and the downstream signalling proteins p21(waf1) and p27(kip1) that control cell cycle. We found a positive correlation between HER3 and HER4 mRNA levels. Compared to normal breast tissue, all four receptors were overexpressed in breast tumors and the strongest overexpression was found at HER3. Compared to normal breast tissue p21Δ, the 19kDa degraded form of p21 protein, was markedly expresses in breast cancer. HER2 expression in breast carcinomas is associated with MARK signal transduction pathway. Then we evaluated these parameters in an in vitro model too, in order to ascertain an intervention inHER signal transduction. Our data reveal a complex expression pattern of HER family in breast tumors and it is this pattern rather than the expression of individual family members that should be taken into account when evaluating novel therapeutics to target these receptors. Our finding also implicate that HER signal transduction pathways can be activated by name different mechanisms that should be targeted together with HERs
Geometry of all supersymmetric type I backgrounds
Creators: name: Gran, U.
name: Papadopoulos, G.
name: Roest, D.
name: Sloane, P.
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We find the geometry of all supersymmetric type I backgrounds by solving the gravitino and dilatino Killing spinor equations, using the spinorial geometry technique, in all cases. The solutions of the gravitino Killing spinor equation are characterized by their isotropy group in Spin(9,1), while the solutions of the dilatino Killing spinor equation are characterized by their isotropy group in the subgroup Sigma(P) of Spin(9,1) which preserves the space of parallel spinors P. Given a solution of the gravitino Killing spinor equation with L parallel spinors, L = 1,2,3,4,5,6,8, the dilatino Killing spinor equation allows for solutions with N supersymmetries for any 0 < N =< L. Moreover for L = 16, we confirm that N = 8,10,12,14,16. We find that in most cases the Bianchi identities and the field equations of type I backgrounds imply a further reduction of the holonomy of the supercovariant connection. In addition, we show that in some cases if the holonomy group of the supercovariant connection is precisely the isotropy group of the parallel spinors, then all parallel spinors are Killing and so there are no backgrounds with N < L supersymmetries.
description: 73 pages. v2: minor changes, references added
Bilateral Gluteal Dyskinesia: Discussion of a Rare Movement Disorder
Creators: name: Sorokin, Anna
name: Mittal, Shivam Om
name: DiCapua, Daniel
name: Jabbari, Bahman
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2014

description: Background: Involuntary movements of gluteal muscles have rarely been reported. Case Report: This 46‐year‐old female with pelvic endometriosis developed involuntary rhythmic movements in the left gluteus maximus, which within a year became bilateral. The movements gradually increased in intensity and interfered with ambulation. Electromyography, at rest, demonstrated almost continuous periodic gluteal discharges, with left‐sided discharges seeming to lead to those on the right. OnabotulinumtoxinA injections into the gluteal muscles improved the movements. Discussion: A rare and previously unreported form of gluteal involuntary movements with periodic electromyographic discharges is described. The cause is uncertain. The differential diagnosis of this unusual movement disorder is discussed, with the most likely diagnosis being myoclonus.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Συσχέτιση παρουσίας γονιδώματος θηλωματοϊών (HPV) και αδενοεξαρτώμενων ιών(AAV) σε φυσιολογικά, δυσπλαστικά και καρκινικά επιχρίσματα από τον τράχηλο της μήτρας
Creators: name: Χρυσάφη, Σοφία Χ.
Publisher: name: Aristotle University of Thessaloniki
Year: 2007
Subjects: Θηλωματοϊοί
Αδενο-εξαρτώμενοι ιοί
HPV
AAV

description: Σκοπός της παρούσας διατριβής ήταν η διερεύνηση του ρόλου των AAV στην εξέλιξη της HPV-επαγόμενης τραχηλικής καρκινογένεσης. Ελέχθησαν 654 γυναίκες, ηλικίας 19-65 ετών. Μετά από κολποσκοπικό και κυτταρολογικό έλεγχο, οι γυναίκες κατανεμήθηκαν σε 3 ομάδες : Α ομάδα ελέγχου, Β' με παρούσα νόσο και Γ. γυναίκες υπό παρακολούθηση έπειτα από θεραπεία για τραχηλικές ενδοεπιθηλιακές αλλοιώσεις. Σύμφωνα με τη σοβαρότητα των βλαβών, οι Β. και Γ., χωρίστηκαν σε ομάδες 4 ομάδες ασθενών : WNL(παθολογικά ευρήματα εντόςφυσιολογικών ορίων), LGCIN(χαμηλού βαθμού αλλοιώσεις) και CA(καρκίνος). Η ανίχνευση των ΑΑV έγινε με τη μέθοδο της φωλαισμένης PCR, ενώ η τυποποίηση των HPV με RFLP-PCR. Το ποσοστό των AAV ανέρχεται στο 17,8% για την ομάδα ελέγχου, ενώ δεν υπήρχαν σημαντικές διαφορές ανάμεσα στις διάφορες ομάδες ασθενών. Οι HPV ανιχνεύθηκαν στο 8,9% των γυναικών της ομάδας ελέγχου, και όπως ήταν αναμενόμενο σε στατιστικά υψηλότερα ποσοστά στις άλλες ομάδες γυναικών(ρ<0,001). Από την περαιτέρω ανάλυση των αποτελεσμάτων προκύπτει ότι η απουσία των ΑΑV στις HPV μολυσμένες γυναίκες αποτελεί παράγοντα κινδύνου, καθώς ο συνδυασμός HPV+/AAV- συναντάται πολύ συχνότερα στις γυναίκες με παθολογικά ευρήματα ποικίλης σοβαρότητας(ρ<0,001, ρ=0,008 και ρ=0,002 για τις LGGN, HGGN και CA ομάδες, αντίστοιχα). Τα αποτελέσματα της παρούσας διατριβής είναι ενδεικτικά της προστατευτικής δράσης των AAV έναντι της HPV- επαγόμενης τραχηλικής νεοπλασίας
description: The aim of this study was to investigate if AAV infections can be associated with a reduced risk for HPV-related cervical neoplasia. The study population consisted of 654 women, aged 19-65 years old. All women, after cytologic and colposcopic evaluation were categorized in 3 groups: A. control group, B. with present cervical pathology and C. with past, treated cervical pathology. Groups B and C were further divided in subgroups according to the severity of the lesions(WNL, LGGIN, HGGIN, CA). AAV and HPV detection were performed by nested-PRC and RFLP-PCR, respectively. AAV was detected in 17,8% of the control group, and there was no statistical difference regarding the different disease and patients groups. The HPV prevalence was, as expected, significantly different between the control group(8,9%) and each of the disease groups(p<0,001). The association between HPV/AAV in B and C patients groups confirmed that the absence of AAVDNA in HPV infected women was correlated with the development of cervical lesions(p<0,001, p=0,008 and p=0,002 for LGGIN, HGGN and CA, respectively). Consequently, AAV probably demonstrates a protective role against the pathologic effects of HPV infections
Additional file 1 of MSC-derived small extracellular vesicles overexpressing miR-20a promoted the osteointegration of porous titanium alloy by enhancing osteogenesis via targeting BAMBI
Creators: name: Liu, Wei
name: Huang, Jinghuan
name: Chen, Feng
name: Xie, Dong
name: Wang, Longqing
name: Ye, Cheng
name: Zhu, Qi
name: Li, Xiang
name: Li, Xiaolin
name: Yang, Lili
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 1.
Spiral Exchange Coupling in Trilayer Magnetic Junction Mediated by Diluted-Magnetic-Semiconductor Thin Film
Creators: name: Lin, Chia-Hui
name: Lin, Hsiu-Hau
name: Hong, Tzay-Ming
Publisher: name: arXiv
Year: 2006
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We revisit the non-collinear exchange coupling across the trilayer magnetic junction mediated by the diluted-magnetic-semiconductor thin film. By numerical approaches, we investigate the spiral angle between the ferromagnetic layers extensively in the parameter space. In contrast to previous study, we discovered the important role of spin relaxation, which tends to favor spiral exchange over the oscillatory Ruderman-Kittel-Kasuya-Yosida interaction. Finally, we discuss the physics origins of these two types of magnetic interactions.
description: 3 pages, 3 figures, accepted for publication in Applied Physics Letters
Parallel Hyperedge Replacement String Languages
Creators: name: Campbell, Graham
Publisher: name: arXiv
Year: 2021
Subjects: subject: Formal Languages and Automata Theory (cs.FL)
subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences
subject: F.4.2; F.4.3

description: There are many open questions surrounding the characterisation of groups with context-sensitive word problem. Only in 2018 was it shown that all finitely generated virtually Abelian groups have multiple context-free word problems, and it is a long-standing open question as to where to place the word problems of hyperbolic groups in the formal language hierarchy. In this paper, we introduce a new language class called the parallel hyperedge replacement string languages, show that it contains all multiple context-free and ET0L languages, and lay down the foundations for future work that may be able to place the word problems of many hyperbolic groups in this class.
description: In Proceedings TERMGRAPH 2020, arXiv:2102.01804. arXiv admin note: substantial text overlap with arXiv:2101.02310
A partial Horn recursion in the cohomology of flag varieties
Creators: name: Richmond, Edward
Publisher: name: arXiv
Year: 2007
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: Horn recursion is a term used to describe when non-vanishing products of Schubert classes in the cohomology of complex flag varieties are characterized by inequalities parameterized by similar non-vanishing products in the cohomology of "smaller" flag varieties. We consider the type A partial flag variety and find that its cohomology exhibits a Horn recursion on a certain deformation of the cup product defined by Belkale and Kumar in \cite{BK06}. We also show that if a product of Schubert classes is non-vanishing on this deformation, then the associated structure constant can be written in terms of structure constants coming from induced Grassmannians.
description: v4: Final version, the current title has been changed from: "Horn recursion for a new product in the cohomology of partial flag varieties SLn/P" to appear in J. Alg. Comb., available through "online first"
Inter-Rater Agreement in the Clinical Diagnosis of Essential Tremor: Data from the NEDICES-2 Pilot Study
Creators: name: Sierra-Hidalgo, Fernando
name: Romero, Juan P.
name: Bermejo-Pareja, Felix
name: Sánchez‐Ferro, Alvaro
name: Hernández‐Gallego, Jesús
name: Posada, Ignacio J.
name: Benito‐León, Julián
name: Louis, Elan D.
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2014

description: Background: Our aim was to assess the diagnostic agreement among the neurologists in the Neurological Disorders in Central Spain 2 (NEDICES‐2) study; these neurologists were assigning diagnoses of essential tremor (ET) vs. no ET. Methods: Clinical histories and standardized video‐taped neurological examinations of 26 individuals (11 ET, seven Parkinson’s disease, three diagnostically unclear, four normal, one with a tremor disorder other than ET) were provided to seven consultant neurologists, six neurology residents, and five neurology research fellows (18 neurologists total). For each of the 26 individuals, neurologists were asked to assign a diagnosis of “ET” or “no ET” using diagnostic criteria proposed by the Movement Disorders Society (MDS). Inter‐rater agreement was assessed both with percent concordance and non‐weighted Κ statistics. Results: Overall Κ was 0.61 (substantial agreement), with no differences between consultant neurologists (Κ = 0.60), neurology residents (Κ = 0.61), and neurology research fellows (Κ = 0.66) in subgroup analyses. Subanalyses of agreement only among those 15 subjects with a previous diagnosis of ET (11 patients) and those with a previous diagnosis of being normal (four individuals) showed an overall Κ of 0.51 (moderate agreement). Discussion In a population‐based epidemiological study, substantial agreement was demonstrated for the diagnosis of ET among neurologists of different levels of expertise. However, agreement was lower than that previously reported using the Washington Heights–Inwood Genetic Study of Essential Tremor criteria, and a head‐to‐head comparison is needed to assess which is the tool of choice in epidemiological research in ET.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
On realizing diagrams of Pi-algebras
Creators: name: Blanc, David
name: Johnson, Mark W
name: Turner, James M
Publisher: name: arXiv
Year: 2006
Subjects: subject: Algebraic Topology (math.AT)
subject: Category Theory (math.CT)
subject: FOS: Mathematics
subject: 18G55, 55P65, 55Q05

description: Given a diagram of Pi-algebras (graded groups equipped with an action of the primary homotopy operations), we ask whether it can be realized as the homotopy groups of a diagram of spaces. The answer given here is in the form of an obstruction theory, of somewhat wider application, formulated in terms of generalized Pi-algebras. This extends a program begun in [J. Pure Appl. Alg. 103 (1995) 167-188] and [Topology 43 (2004) 857-892] to study the realization of a single Pi-algebra. In particular, we explicitly analyze the simple case of a single map, and provide a detailed example, illustrating the connections to higher homotopy operations.
description: This is the version published by Algebraic & Geometric Topology on 21 June 2006
Long-Period Objects in the Extrasolar Planetary Systems 47 UMa and 14 Her
Creators: name: Wittenmyer, Robert A.
name: Endl, Michael
name: Cochran, William D.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The possible existence of additional long-period planetary-mass objects in the extrasolar planetary systems 47 UMa and 14 Her is investigated. We combine all available radial-velocity data on these stars, spanning up to 18 years. For the 47 UMa system, we show that while a second planet improves the fit to all available data, there is still substantial ambiguity as to the orbital parameters of the proposed planetary companion 47 UMa c. We also present new observations which clearly support a long-period companion in the 14 Her system. With a period of 6906+/-70 days, 14 Her c may be in a 4:1 resonance with the inner planet. We also present revised orbital solutions for 7 previously known planets incorporating recent additional data obtained with the 2.7m Harlan J. Smith Telescope at McDonald Observatory.
description: Accepted for publication in ApJ
Soviet influence in the Third World : indicators of influence
Creators: name: Smith, Kevin Michael
Publisher: name: University of British Columbia
Year: 2011

description: Discussion of the influence of the Soviet Union is often in vague terms. The term "Soviet influence" is usually used without concern for its clear definition. This paper attempts to deal with the notion of Soviet influence as it relates to the Third World, and to analyse the extent of Soviet influence in Third World nations. In doing this, three main questions are asked: What is influence? What evidence is there of Soviet influence? Can Soviet influence be measured? First, the notion of influence is defined. Second, criteria — the indicators of influence — for identifying and measuring, relatively, Soviet influence in the Third World are outlined and evaluated. The indicators form a simple methodology for examining Soviet influence. Third, the indicators are applied to two case studies — Somalia during the 1960s and 1970s, and Angola during the same time period. The indicators are: 1/ Domestic Dissonance 2/ Soviet Acquisition of Military, Naval and Air Facilities 3/ Soviet Goals and Objectives 4/ Attitudes and Perceptions of B 5/ Quantitative Measures of Trade, Aid and Personnel 6/ The Treaty of Friendship and Co-operation 7/ A Vanguard Party Certain indicators are of less significance than is usually assumed: the Treaty of Friendship and Co-operation, the Vanguard Party, Quantitative Measures of Trade and Aid, and Soviet Acquisition of Facilities. The most valuable indicators are Attitudes and Perceptions, Domestic Dissonance and possibly Personnel. The use of these indicators in conjunction with the analysis of a specific incident of attempted Soviet influence can determine the extent of Soviet influence. Analysts tend to attribute significant influence to the Soviet Union. However, often what is assumed to be significant influence involves mutual benefits and\or a lack of commitment to the issue by the Third World nation. Two factors are very important for determining the extent of Soviet influence: (1) The importance of the issue to the Third World nation; (2) The degree of conflict between Soviet objectives and those of the Third World nation. In the Somalia and Angola case studies, the extent of Soviet influence became evident when the Third World nation's vital interests were at stake. It is important not to over estimate Soviet influence, or to equate Soviet influence with Soviet control over a nation. The key to analysing inter-nation influence is realising that its extent can vary and it does have limitations.
Treatment of Essential Tremor with Long-chain Alcohols: Still Experimental or Ready for Prime Time?
Creators: name: Haubenberger, Dietrich
name: Nahab, Fatta B.
name: Voller, Bernhard
name: Hallett, Mark
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2014

description: Aim: To review current literature on long‐chain alcohols and their derivatives as novel pharmacotherapy for the treatment of essential tremor (ET). Background: Currently available and recommended pharmacotherapies for ET are often limited by suboptimal treatment effects, frequent adverse effects, and drug interactions. While ethanol is reported to profoundly decrease tremor severity in the majority of patients with ET, preclinical experience suggests that long‐chain alcohols such as 1‐octanol might lead to a comparable tremor reduction without ethanol’s typical side effects of sedation and intoxication. Here, we review the literature on the first clinical trials on 1‐octanol and its metabolite octanoic acid (OA) for the treatment of ET. Methods: The literature on preclinical and clinical trials on long‐chain alcohols as well as OA was reviewed and summarized, and an outlook given on next phases of development. Discussion: 1‐octanol was demonstrated to be safe and effective in a double‐blind, placebo‐controlled low‐dose trial, and open‐label data showed excellent tolerability and dose‐dependent efficacy up to 128 mg/kg. Despite 1‐octanol’s efficacy, its future viability as an effective therapy is limited by its pharmacological properties that require large volumes to be orally administered. Pharmacokinetic data indicate that OA is the active metabolite of 1‐octanol. Preclinical efficacy data for OA are positive, and human pilot data demonstrated excellent safety as well as efficacy in secondary outcome measures of tremor amplitudes. OA also has more favorable pharmacological properties for drug delivery; hence, OA may be worth developing as a pharmaceutical.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Study of the Surface of 2003 EL61: the largest carbon-depleted object in the trans-neptunian belt
Creators: name: Pinilla-ALonso, N.
name: Brunetto, R.
name: Licandro, J.
name: Gil-Hutton, R.
name: Roush, T. L.
name: Strazzulla, G.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: 2003 EL61 is the largest member of a group of TNOs with similar orbits and 'unique' spectra (neutral slope in the visible and the deepest water ice absorption bands ever observed in the TNb). Studying the composition of the surface of 2003 EL61 provides useful constrains on the origin of this particular group of TNOs and on the outer Solar system's history. We present visible and near-infrared spectra of 2003 EL61 obtained with the 4.2m WHT and the 3.6m TNG at the Roque de los Muchachos Observatory (Canary Islands, Spain). Near infrared spectra were obtained at different rotational phases covering almost one complete rotational period. Spectra are fitted using Hapke scattering models and constraints on the surface composition are derived. No significant variations in the spectral slope and in the depth of the water ice absorption bands at different rotational phases are evident, suggesting that the surface of 2003 EL61 is homogeneous. The scattering models show that a 1:1 intimate mixture of crystalline and amorphous water ice is the most probable composition for the surface of this TNO, and constrain the presence of other minor constituents to a maximum of 8% The derived composition suggests that: a) cryovolcanism is unlikely to be the main resurfacing process responsible for the high presence of water ice on the surface of these bodies; b) the surface is older than 10^8 yr. Any catastrophic event, like the collision suggested to be the origin of this population, had to happen at least 10^8 yr ago; c) the surface of 2003 EL61 is depleted of carbon chains. According to the orbital parameters of this population, this makes it a possible source of carbon-depleted Jupiter family comets.
description: 9 pages, 7 graphs. Keywords: water ice, carbon-depleted, Kuiper Belt, astrochemistry, spectroscopy
Revealing a New Black Widow Binary 4FGL J0336.0+7502
Creators: name: Li, Kwan-Lok
name: Yap, Y. X. Jane
name: Hui, Chung Yue
name: Kong, Albert K. H.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We report on a discovery of a promising candidate as a black widow millisecond pulsar binary, 4FGL J0336.0+7502, which shows many pulsar-like properties in the 4FGL-DR2 catalog. Within the 95% error region of the LAT source, we identified an optical counterpart with a clear periodicity at P(orb) = 3.718178(9) hours using the Bohyunsan 1.8-m Telescope, Lulin One-meter Telescope, Canada-France-Hawaii Telescope, and Gemini-North. At the optical position, an X-ray source was marginally detected in the Swift/XRT archival data, and the detection was confirmed by our Chandra/ACIS DDT observation. The spectrum of the X-ray source can be described by a power-law model of Gamma = 1.6+/-0.7 and F(0.3-7keV) = 3.5e-14 erg/cm^2/s. The X-ray photon index and the low X-ray-to-gamma-ray flux ratio (i.e., < 1%) are both consistent with that of many known black widow pulsars. There is also a hint of an X-ray orbital modulation in the Chandra data, although the significance is very low (1.3 sigma). If the pulsar identity and the X-ray modulation are confirmed, it would be the fifth black widow millisecond pulsar binary that showed an orbitally-modulated emission in X-rays.
description: 7 pages, including 5 figures and 2 table. Accepted for publication in ApJ
Rescue GPi-DBS for a Stroke Associated Hemiballism in a Patient with STN-DBS
Creators: name: Oyama, Genko
name: Maling, Nicholas
name: Avila‐Thompson, Amanda
name: Zeilman, Pam R.
name: Foote, Kelly D.
name: Malaty, Irene A.
name: Rodriguez, Ramon L.
name: Okun, Michael S.
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2014

description: Background: Hemiballism/hemichorea commonly occurs as a result of a lesion in the subthalamic region. Case Report: A 38‐year‐old male with Parkinson’s disease developed intractable hemiballism in his left extremities due to a small lesion that was located adjacent to the right deep brain stimulation (DBS) lead, 10 months after bilateral subthalamic nucleus (STN)‐DBS placement. He underwent a right globus pallidus internus (GPi)‐DBS lead implantation. GPi‐DBS satisfactorily addressed his hemiballism. Discussion: This case offered a unique look at basal ganglia physiology in human hemiballism. GPi‐DBS is a reasonable therapeutic option for the treatment of medication refractory hemiballism in the setting of Parkinson’s disease.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Induced model structures for higher categories
Creators: name: Hackney, Philip
name: Rovelli, Martina
Publisher: name: arXiv
Year: 2021
Subjects: subject: Category Theory (math.CT)
subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics

description: We give a new criterion guaranteeing existence of model structures left-induced along a functor admitting both adjoints. This works under the hypothesis that the functor induces idempotent adjunctions at the homotopy category level. As an application, we construct new model structures on cubical sets, prederivators, marked simplicial sets and simplicial spaces modeling $\infty$-categories and $\infty$-groupoids.
description: 15 pages, to appear in Proc. Amer. Math. Soc
White-box Audio VST Effect Programming
Creators: name: Mitcheltree, Christopher
name: Koike, Hideki
Publisher: name: arXiv
Year: 2021
Subjects: subject: Sound (cs.SD)
subject: Machine Learning (cs.LG)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Learning to program an audio production VST plugin is a time consuming process, usually obtained through inefficient trial and error and only mastered after extensive user experience. We propose a white-box, iterative system that provides step-by-step instructions for applying audio effects to change a user's audio signal towards a desired sound. We apply our system to Xfer Records Serum: currently one of the most popular and complex VST synthesizers used by the audio production community. Our results indicate that our system is consistently able to provide useful feedback for a variety of different audio effects and synthesizer presets.
description: The latest version of the system is to appear at EvoMUSART 2021 as a full paper. Audio samples of the latest system can be listened to at https://bit.ly/serum_rnn
Effect of convective outer layers modeling on non-adiabatic seismic observables of delta Scuti stars
Creators: name: Montalban, J.
name: Dupret, M. -A.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The identification of pulsation modes in delta Scuti stars is mandatory to constrain the theoretical stellar models. The non-adiabatic observables used in the photometric identification methods depend, however,on convection modeling in the external layers. Our aim is to determine how the treatment of convection in the atmospheric and sub-atmospheric layers affects the mode identification, and what information about the thermal structure of the external layers can be obtained from amplitude ratios and phase lags in Strömgren photometric bands. We derive non-adiabatic parameters for delta Scuti stars by using, for the first time, stellar models with the same treatment of convection in the interior and in the atmosphere. We compute classical non-gray mixing length models, and as well non-gray ``Full Spectrum of Turbulence'' models. Furthermore, we compute the photometric amplitudes and phases of pulsation by using the colors and the limb-darkening coefficents as derived from the same atmosphere models used in the stellar modeling. We show that the non-adiabatic phase-lag is mainly sensitive to the thermal gradients in the external layers, (and hence to the treatment of convection), and that this sensitivity is also clearly reflected in the multi-color photometric phase differences.
description: 14 pag. 19 figs. accepted for publication in Astronomy and Astrophysics
Monito agli stampatori (Wittenberg, 1541)
Creators: name: Luther, Martin
name: Pievatolo, Maria Chiara
Publisher: name: Zenodo
Year: 2009

description: Traduzione dall'originale tedesco di Maria Chiara Pievatolo. Fonte: Württembergische Landesbibliothek Signatur: Bb deutsch 154503, ristampa del 1545, ora in 'Luther's "Warning to the Printers"', Primary Sources on Copyright (1450-1900) eds L. Bently & M. Kretschmer.
Anomalous Freezing of Low Dimensional Water Confined in Graphene Nanowrinkles
Creators: name: Verhagen, Tim
name: Klimes, Jiri
name: Pacakova, Barbara
name: Kalbac, Martin
name: Vejpravova, Jana
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Various properties of water are affected by confinement as the space-filling of the water molecules is very different from bulk water. In our study, we challenged the creation of a stable system in which water molecules are permanently locked in nanodimensional graphene traps. For that purpose, we developed a technique, nitrocellulose-assisted transfer of graphene grown by chemical vapor deposition, which enables capturing of the water molecules below an atomically thin graphene membrane structured into a net of regular wrinkles with a lateral dimension of about 4 nm. After successfully confining water molecules below a graphene monolayer, we employed cryogenic Raman spectroscopy to monitor the phase changes of the confined water as a function of the temperature. In our experiment system, the graphene monolayer structured into a net of fine wrinkles plays a dual role: (i) it enables water confinement and (ii) serves as an extremely sensitive probe for phase transitions involving water via graphene-based spectroscopic monitoring of the underlying water structure. Experimental findings were supported with classical and path integral molecular dynamics simulations carried out on our experimental system.
description: 27 pages, 3 Figures + 1 Cover Image
Clinical Classification of Borderline Cases in the Family Study of Essential Tremor: An Analysis of Phenotypic Features
Creators: name: Louis, Elan D.
name: Ottman, Ruth
name: Clark, Lorraine N.
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2014

description: Background: In genetic research on essential tremor (ET), certain individuals may be particularly challenging to categorize diagnostically. Methods: In the Family Study of Essential Tremor (>200 enrollees), 28 participants with borderline clinical findings who did not meet strict criteria for ET were assigned final diagnoses of ET. We scrutinized the clinical features of these cases and the sensitivity/specificity of certain features that best separated them from 19 unaffected individuals. Results: Borderline ET cases differed from unaffected individuals in eight features: total tremor score, at least one kinetic tremor rating ≥1.5, at least one kinetic tremor rating ≥1.5 in the dominant arm, tremor rating during spiral drawing ≥1.5, higher spiral axis score, head tremor, complaint of tremor, and comment on tremor by others. The combination of at least one kinetic tremor rating ≥1.5 in the dominant arm and the presence of at least three of the remaining seven features predicted the clinician‐assigned diagnosis in 88.6% of borderline ET vs. unaffected individuals (sensitivity 84.6%, specificity 94.4%). Discussion: In a family study, a small number of clinical features characterized borderline ET, and a particular combination of these separated the majority of these borderline cases from normals. These analyses may help researchers minimize diagnostic misclassification.
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
The ATESP 5 GHz radio survey I. Source counts and spectral index properties of the faint radio population
Creators: name: Prandoni, I.
name: Parma, P.
name: Wieringa, M. H.
name: de Ruiter, H. R.
name: Gregorini, L.
name: Mignano, A.
name: Vettolani, G.
name: Ekers, R. D.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: [Abridged] The nature and evolutionary properties of the faint radio population, responsible for the steepening observed in the 1.4 GHz source counts below 1 milliJy, are not yet entirely clear. Radio spectral indices may help to constrain the origin of the radio emission in such faint radio sources and may be fundamental in understanding eventual links to the optical light. We study the spectral index behaviour of sources that were found in the 1.4 GHz ATESP survey (Prandoni et al. 2000a,b). Using the Australia Telescope Compact Array we observed at 5 GHz part of the region covered by the sub-mJy ATESP survey. In particular we imaged a one square degree area for which deep optical imaging in UBVRIJK is available. In this paper we present the 5 GHz survey and source catalogue, we derive the 5 GHz source counts and we discuss the 1.4-5 GHz spectral index properties of the ATESP sources. The analysis of the optical properties of the sample will be the subject of a following paper. The 5 GHz survey has produced a catalogue of 111 radio sources, complete down to a (6 sigma) limit S_lim(5 GHz)~0.4 mJy. We take advantage of the better spatial resolution at 5 GHz (~2 arcsec compared to ~8 arcsec at 1.4 GHz) to infer radio source structures and sizes. The 5 GHz source counts derived by the present sample are consistent with those reported in the literature, but improve significantly the statistics in the flux range 0.4< S(5 GHz)<1 mJy. The ATESP sources show a flattening of the 1.4-5 GHz spectral index with decreasing flux density, which is particularly significant for the 5 GHz selected sample. Such a flattening confirm previous results coming from smaller samples and is consistent with a flattening of the 5 GHz source counts occurring at fluxes <=0.5 mJy.
description: 22 pages, 13 figures Accepted for publication on Astronomy and Astrophysics. Replaced version: corrected typos and references updated
Algebraic derivation of neural networks and its applications in image processing
Creators: name: Shi, Pingnan
Publisher: name: University of British Columbia
Year: 2011

description: Artificial neural networks are systems composed of interconnected simple computing units known as artificial neurons which simulate some properties of their biological counterparts. They have been developed and studied for understanding how brains function, and for computational purposes. In order to use a neural network for computation, the network has to be designed in such a way that it performs a useful function. Currently, the most popular method of designing a network to perform a function is to adjust the parameters of a specified network until the network approximates the input-output behaviour of the function. Although some analytical knowledge about the function is sometimes available or obtainable, it is usually not used. Some neural network paradigms exist where such knowledge is utilized; however, there is no systematical method to do so. The objective of this research is to develop such a method. A systematic method of neural network design, which we call algebraic derivation methodology, is proposed and developed in this thesis. It is developed with an emphasis on designing neural networks to implement image processing algorithms. A key feature of this methodology is that neurons and neural networks are represented symbolically such that a network can be algebraically derived from a given function and the resulting network can be simplified. By simplification we mean finding an equivalent network (i.e., performing the same function) with fewer layers and fewer neurons. A type of neural networks, which we call LQT networks, are chosen for implementing image processing algorithms. Theorems for simplifying such networks are developed. Procedures for deriving such networks to realize both single-input and multiple-input functions are given. To show the merits of the algebraic derivation methodology, LQT networks for implementing some well-known algorithms in image processing and some other areas are developed by using the above mentioned theorems and procedures. Most of these networks are the first known such neural network models; in the case there are other known network models, our networks have the same or better performance in terms of computation time.
Efficient Riccati recursion for optimal control problems with pure-state equality constraints
Creators: name: Katayama, Sotaro
name: Ohtsuka, Toshiyuki
Publisher: name: arXiv
Year: 2021
Subjects: subject: Optimization and Control (math.OC)
subject: Robotics (cs.RO)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: A novel approach to efficiently treat pure-state equality constraints in optimal control problems (OCPs) using a Riccati recursion algorithm is proposed. The proposed method transforms a pure-state equality constraint into a mixed state-control constraint such that the constraint is expressed by variables at a certain previous time stage. It is showed that if the solution satisfies the second-order sufficient conditions of the OCP with the transformed mixed state-control constraints, it is a local minimum of the OCP with the original pure-state constraints. A Riccati recursion algorithm is derived to solve the OCP using the transformed constraints with linear time complexity in the grid number of the horizon, in contrast to a previous approach that scales cubically with respect to the total dimension of the pure-state equality constraints. Numerical experiments on the whole-body optimal control of quadrupedal gaits that involve pure-state equality constraints owing to contact switches demonstrate the effectiveness of the proposed method over existing approaches.
description: 8 pages, 3 figures. This paper has been accepted to be presented at 2022 Americal Control Conference (ACC2022)
Noether theorem in stochastic optimal control problems via contact symmetries
Creators: name: De Vecchi, Francesco C.
name: Mastrogiacomo, Elisa
name: Turra, Mattia
name: Ugolini, Stefania
Publisher: name: arXiv
Year: 2021
Subjects: subject: Optimization and Control (math.OC)
subject: Probability (math.PR)
subject: Mathematical Finance (q-fin.MF)
subject: FOS: Mathematics
subject: FOS: Economics and business
subject: 93E20, 58D19, 91G10, 60H15

description: We establish a generalization of Noether theorem for stochastic optimal control problems. Exploiting the tools of jet bundles and contact geometry, we prove that from any (contact) symmetry of the Hamilton-Jacobi-Bellman equation associated to an optimal control problem it is possible to build a related local martingale. Moreover, we provide an application of the theoretical results to Merton's optimal portfolio problem, showing that this model admits infinitely many conserved quantities in the form of local martingales.
Isolated Chorea Associated with LGI1 Antibody
Creators: name: Ramdhani, Ritesh A.
name: Frucht, Steven J.
Publisher: name: Tremor and Other Hyperkinetic Movements
Year: 2014

description: Background: Leucine‐rich glioma inactivated 1 (LGI1) antibody produces a syndrome of limbic encephalitis, hyponatremia, and facio‐brachial dystonic seizures that is non‐paraneoplastic and responsive to corticosteroids. Parkinsonism, tremor, and generalized chorea are rare manifestations of LGI1, but, when present, commonly accompany other signs of limbic encephalitis. Case Report: We present a case of LGI1‐related isolated chorea in a 53‐year‐old Japanese male. His chorea responded to high‐dose steroids, suggesting a potential role for this synaptic antibody in triggering chorea. Discussion: This case highlights a new treatable etiology of chorea. This article prompted a response letter: Vynogradova I, Savitski V, Heckmann JG. Hemichorea associated with CASPR2 antibody. Tremor Other Hyperkinet Mov. 2014; 4. doi: 10.7916/D8VM49C5 The authors' response to the letter: Ramdhani RA, Frucht SJ. Reply to: hemichorea associated with CASPR2 antibody. Tremor Other Hyperkinet Mov. 2014; 4. doi: 10.7916/D8QV3JM0
description: Tremor and Other Hyperkinetic Movements, Tremor and Other Hyperkinetic Movements
Tip-induced domain protrusion in ferroelectric films with in-plane polarization
Creators: name: Kondovych, S.
name: Gruverman, A.
name: Luk'yanchuk, I.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Charge manipulation and fabrication of stable domain patterns in ferroelectric materials by scanning probe microscopy open up broad avenues for the development of tunable electronics. Harnessing the polarization energy and electrostatic forces with specific geometry of the system enables producing the nanoscale domains by-design. Along with that, domain engineering requires mastery of underlying physical mechanisms that govern the domain formation. Here, we present a theoretical description of the domain formation by a scanning probe microscopy tip in a ferroelectric film with strong in-plane anisotropy of polarization. We demonstrate that local charge injection produces wedge-shaped domains that propagate along the anisotropy axis, whereas the tip-written lines of charge generate a comb-like domain structure. The results of our calculations agree with earlier experimental observations and allow for the optimization of the targeted domain structures.
description: 5 pages, 3 figures