cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Characterization of Thin Liquid Films on Surfaces with Small Scale Roughness by Optical Interferometry
Creators: name: Lai, Helen Ann
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified

description: Two-phase heat transfer techniques such a boiling make use of the high latent heat of fluids to enable dissipation of higher heat fluxes from surfaces compared to conventional single-phase cooling methods. To meet the increasing heat flux dissipation requirements of high-power electronic devices, modifications to the surface properties and roughness are often considered as a means to enhance two-phase heat transfer processes. Although surface roughness of varying length scales has been observed experimentally to enhance boiling heat transfer performance, the physical mechanisms that govern this improvement are not widely accepted. Correlations can be developed to map the behavior of specific surface structure geometries, but a broader investigation of the fundamental forces affecting evaporation at the three-phase contact line, which is critically important to the two-phase heat transfer process, may provide more widely applicable insights. In this thesis, an experimental setup was developed to investigate the effect of small scale surface roughness, with feature sizes below 1 micron, on the liquid film profile of a meniscus formed on a surface. This physical film profile can provide insight into how the surface roughness affects disjoining pressure, an important force that affects the phase change heat transfer process at the contact line. Using an interferometry technique to measure the liquid film profile for a model system of octane on silicon substrate with varying roughness, the change in disjoining pressure in the liquid film was observed. We found that the strength of disjoining pressure in the liquid film increases with increasing surface roughness feature depth.
Pyoderma outbreak among kindergarten families: Association with a Panton-Valentine leukocidin (PVL)-producing S. aureus strain
Creators: name: Leistner, Rasmus
name: Kola, Axel
name: Gastmeier, Petra
name: Krüger, Renate
name: Hoppe, Pia-Alice
name: Schneider-Burrus, Sylke
name: Zuschneid, Irina
name: Wischnewski, Nicoletta
name: Bender, Jennifer K.
name: Layer, Franziska
name: Niebank, Michaela
name: Scheibenbogen, Carmen
name: Hanitsch, Leif G.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2017
Subjects: subject: 610 Medizin

description: Objectives: We report on an outbreak of skin and soft tissue infections (SSTI) among kindergarten families. We analyzed the transmission route and aimed to control the outbreak. Methods: The transmission route was investigated by nasal screening for Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus (PVL-SA), subsequent microbiological investigation including whole genome sequencing and a questionnaire-based analysis of epidemiological information. The control measures included distribution of outbreak information to all individuals at risk and implementation of a Staphylococcus aureus decontamination protocol. Results: Individuals from 7 of 19 families were either colonized or showed signs of SSTI such as massive abscesses or eye lid infections. We found 10 PVL-SA isolates in 9 individuals. In the WGS-analysis all isolates were found identical with a maximum of 17 allele difference. The clones were methicillin-susceptible but cotrimoxazole resistant. In comparison to PVL-SAs from an international strain collection, the outbreak clone showed close genetical relatedness to PVL-SAs from a non-European country. The questionnaire results showed frequent travels of one family to this area. The results also demonstrated likely transmission via direct contact between families. After initiation of Staphylococcus aureus decontamination no further case was detected. Conclusions: Our outbreak investigation showed the introduction of a PVL-SA strain into a kindergarten likely as a result of international travel and further transmission by direct contact. The implementation of a Staphylococcus aureus decontamination protocol was able to control the outbreak.
Additional file 6 of Integrated transcriptomic and metabolomic analyses reveals anthocyanin biosynthesis in leaf coloration of quinoa (Chenopodium quinoa Willd.)
Creators: name: Zhang, Min
name: Li, Yueyou
name: Wang, Junling
name: Shang, Shaopu
name: Wang, Hongxia
name: Yang, Xinlei
name: Lu, Chuan
name: Wang, Mei
name: Sun, Xinbo
name: Liu, Xiaoqing
name: Wang, Xiaoxia
name: Wei, Boxiang
name: Lv, Wei
name: Mu, Guojun
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 6
Etiology of nephrotic syndrome: insights from univariate and multivariate Mendelian randomization study
Creators: name: Chan, Han
name: Yin, Hui
name: Yang, Xueying
name: Zhang, Gaofu
name: Wang, Mo
name: Yang, Haiping
name: Li, Qiu
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Mental Health
subject: Computational Biology

description: Nephrotic syndrome (NS) is a common cause of chronic glomerular disease. However, the precise way in which one or more risk exposure traits of renal injury lead to NS remains unclear. In this study, we systematically examined the causal relationships between NS and various exposure traits, including traits related to chronic hepatitis B/C infection, COVID-19 (hospitalized), general allergy status, herbal tea intake, immunoglobulin E, childhood obesity, and the human leukocyte antigen (HLA)-II histocompatibility DM α/DP β1/DQ α2 chain, via multivariate Mendelian randomization (MVMR). A previously reported exposure trait, ulcerative colitis, was also included to analyze the independent effect of each significant exposure on the risk of developing NS. In the univariable MR analysis, immunoglobulin E (OR = 5.62, 95% CI = 2.91–10.84, p = 2.67 × 10−7) and the HLA-II histocompatibility DQ α2 chain (OR = 0.70, 95% CI = 0.63–0.80, p = 2.83 × 10−7) were shown to have effect estimates consistent with a greater risk of developing NS. The reverse MR analysis showed no evidence of causal effect from NS to histocompatibility DQ α2 chain (p = 0.76). In MVMR, only the HLA-II histocompatibility DQ α2 chain retained a robust effect (OR = 0.71, 95% CI = 0.61–0.82; p = 9.39 × 10−6), and the estimate for immunoglobulin E was weakened (OR = 1.04, 95% CI = 0.60–2.13; p = 0.92). With two independent ulcerative colitis resources used for validation, ulcerative colitis was not significantly associated with NS. This study provides genetic evidence that the HLA-II histocompatibility DQ α2 chain has a predominant causal effect on the risk of developing NS. HLA-II histocompatibility-mediated immune abnormalities may lead to subtypes of NS and its pathological changes.
The Effectiveness of Explicit Pedagogical Intervention in the L2 Perception and Production of German Vowels
Creators: name: Bryan, Adrial D
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: German language

description: The purpose of this study was twofold. Firstly, this study sought to capture second semester language students’ auditory perception of German vowels. Secondly, this study sought to investigate the effectiveness of direct pronunciation instruction in enhancing learners’ perception and consequent production of German vowels. Vowels were selected to be analyzed in this study, as they are the nucleus of words (Derwing, Thomson, Foote, & Munro, 2012). Front rounded vowels in German were given particular attention, as they do not exist in English, and they frequently pose as a challenge for native English-speakers to learn (O’Brien & Fagan, 2016, Hall, 2003). This study was conducted at a large midwestern U.S. university. The project consisted of 47 participants which were divided into experimental and control groups. Throughout the duration of the study, students were administered a biographical survey, and a pre- and post-test which consisted of a listening identification exercise and speaking assessment. Participants in the test group were also offered a lesson on the German phonemic system as it relates to German vowels. Upon the completion of the study, the data analyzed did not yield any significant results. Students’ scores on the perception and production exercises taken from both the pre- and post-tests remained largely stagnant. This was true for the test scores taken from the experimental and control groups. Though the study outcomes did not produce the hypothesized results, they do underscore the need for long-term explicit pronunciation instruction in the language classroom.
sj-pdf-7-jva-10.1177_11297298211031339 – Supplemental material for Trendelenburg position for internal jugular vein catheterization: A systematic review and meta-analysis
Creators: name: Garcia-Leal, Mariana
name: Guzman-Lopez, Santos
name: Verdines-Perez, Adrian Manuel
name: de Leon-Gutierrez, Humberto
name: Fernandez-Rodarte, Bernardo Alfonso
name: Alvarez-Villalobos, Neri Alejandro
name: Martinez-Garza, Javier Humberto
name: Quiroga-Garza, Alejandro
name: Elizondo-Omaña, Rodrigo Enrique
Publisher: name: SAGE Journals
Year: 2021
Subjects: Cardiology

description: Supplemental material, sj-pdf-7-jva-10.1177_11297298211031339 for Trendelenburg position for internal jugular vein catheterization: A systematic review and meta-analysis by Mariana Garcia-Leal, Santos Guzman-Lopez, Adrian Manuel Verdines-Perez, Humberto de Leon-Gutierrez, Bernardo Alfonso Fernandez-Rodarte, Neri Alejandro Alvarez-Villalobos, Javier Humberto Martinez-Garza, Alejandro Quiroga-Garza and Rodrigo Enrique Elizondo-Omaña in The Journal of Vascular Access
Additional file 7 of Integrated transcriptomic and metabolomic analyses reveals anthocyanin biosynthesis in leaf coloration of quinoa (Chenopodium quinoa Willd.)
Creators: name: Zhang, Min
name: Li, Yueyou
name: Wang, Junling
name: Shang, Shaopu
name: Wang, Hongxia
name: Yang, Xinlei
name: Lu, Chuan
name: Wang, Mei
name: Sun, Xinbo
name: Liu, Xiaoqing
name: Wang, Xiaoxia
name: Wei, Boxiang
name: Lv, Wei
name: Mu, Guojun
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 7
Gaps in vaccine clinical trials in Africa: A mixed scoping review and bibliometric analysis before, during, and post- COVID-19 pandemic
Creators: name: Uthman, Olalekan A.
name: Katoto, Patrick D.M.C
name: Anjorin, Seun S.
name: Marais, Thinus
name: Amiche, Amine
name: Nachega, Jean B.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Africa’s participation in vaccine trials has historically been limited, but the COVID-19 pandemic highlighted the need for greater involvement. This study explores vaccine clinical development in Africa, emphasizing its importance for global health security. Using a scoping review and bibliometric analysis, we examined 662 vaccine trials conducted before, during, and after the pandemic. The analysis revealed a significant increase in vaccine trials after 2018 and particularly following the end of the COVID-19 pandemic in May 2023. Most trials focused on viral infections and were single-country studies. Pharmaceutical company sponsors funded most of the earlier trials, with increased government and academic involvement post-2020. Despite progress, challenges remain in the geographic distribution of trials, the number of government-supported studies, and the diversity of conditions studied. Addressing these gaps is crucial to bolstering Africa’s role in global vaccine development.
Pollutant and Inflammation marker detection using low-cost and portable microfluidic platform, and flexible microelectronic platform
Creators: name: Lin, Li-Kai
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Biomaterials
Nanomaterials
Functional materials
Macromolecular and materials chemistry not elsewhere classified
Inorganic materials (incl. nanomaterials)
Macromolecular materials
Structure and dynamics of materials
Materials engineering not elsewhere classified

description: Existing methods for pathogen/pollutant detection or wound infection monitoring employ high-cost instruments that could only be operated by trained personnel, and costly device-based detection requires a time-consuming field-to-lab process. This expensive process with multiple prerequisites prolongs the time that patients must wait for a diagnosis. Therefore, improved methods for point-of-care biosensing are necessary. In this study, we aimed to develop a direct, easy-to-use, portable, low cost, highly sensitive and selective sensor platform with the goal of pollutant detection and wound infection/cancer migration monitoring. This study has two main parts, including microfluidic, electrical, and optical sensing platforms. The first part, including chapters 2, 3, and 4, focuses on Bisphenol A (BPA) lateral flow assay (LFA) detection; the second part, including chapter 5 focuses on the electrical sensing platform fabrication for one of the markers of inflammation, matrix metalloproteinases-9 (MMP-9), monitoring/detection. In chapters 2, 3, and 4, we found that the few lateral flow assays (LFAs) established for detecting the endocrine-disrupting chemical BPA have employed citrate-stabilized gold nanoparticles (GNPs), which have inevitable limitations and instability issues. To address these limitations, in chapter 2, a more stable and more sensitive biosensor is developed by designing strategies for modifying the surfaces of GNPs with polyethylene glycol and then testing their effectiveness and sensitivity toward BPA in an LFA. In chapter 3, we describe the development of a new range-extended bisphenol A (BPA) detection method that uses a surface enhanced Raman scattering lateral flow assay (SERS-LFA) binary system. In chapter 4, we examine advanced bisphenol A (BPA) lateral flow assays (LFAs) that use multiple nanosystems. The assays include three nanosystems, namely, gold nanostars, gold nanocubes, and gold nanorods, which are rarely applied in LFAs, compared with general gold nanoparticles. The developed LFAs show different performances in the detection of BPA. In chapter 5, a stable electrical sensing platform is developed for MMP-9 detection.
sj-pdf-2-jhs-10.1177_17531934211027499 - Supplemental material for Hyperselective neurectomy for the treatment of upper limb spasticity in adults and children: a prospective study
Creators: name: Leclercq, Caroline
name: Perruisseau-Carrier, Anne
name: Gras, Mathilde
name: Panciera, Paolo
name: Fulchignoni, Camillo
name: Fulchignoni, Marcello
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-2-jhs-10.1177_17531934211027499 for Hyperselective neurectomy for the treatment of upper limb spasticity in adults and children: a prospective study by Caroline Leclercq, Anne Perruisseau-Carrier, Mathilde Gras, Paolo Panciera, Camillo Fulchignoni and Marcello Fulchignoni in Journal of Hand Surgery (European Volume)
Threat, Memory, and Framing: The Development of South Korea’s Democracy Movement, 1979-1987
Creators: name: Park, Soon Seok
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Sociology not elsewhere classified

description: This dissertation research focuses on the development of South Korea’s democracy movement from 1979 to 1987, a time that was marked by two waves of sustained protest: one of which was brutally repressed while the other led to a transition to democracy. This dissertation examines the cultural processes at work during the period between these two waves. This study builds a dataset drawing on archival data in the form of memoirs, diaries, leaflets and brochures, minutes, statements, and testimonies of activists and activist organizations as well as newspaper reports and government documents. Using the dataset, this study advances scholarship on contentious politics and democratization by revising and expanding three theoretical concepts: threat, memory work, and framing.
sj-pdf-1-jcb-10.1177_0271678X211031321 - Supplemental material for A CBF decrease in the left supplementary motor areas: New insight into postoperative pediatric cerebellar mutism syndrome using arterial spin labeling perfusion MRI
Creators: name: Boisgontier, Jennifer
name: Fillon, Ludovic
name: Rutten, Caroline
name: Saitovitch, Ana
name: Dufour, Christelle
name: Lemaître, Hervé
name: Beccaria, Kévin
name: Blauwblomme, Thomas
name: Levy, Raphaël
name: Dangouloff-Ros, Volodia
name: Grévent, David
name: Roux, Charles-Joris
name: Grill, Jacques
name: Vinçon-Leite, Alice
name: Saidoun, Lila
name: Bourdeaut, Franck
name: Zilbovicius, Monica
name: Boddaert, Nathalie
name: Puget, Stéphanie
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine
subject: 110306 Endocrinology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 110320 Radiology and Organ Imaging
subject: Cell Biology
subject: Biochemistry
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Neuroscience

description: Supplemental material, sj-pdf-1-jcb-10.1177_0271678X211031321 for A CBF decrease in the left supplementary motor areas: New insight into postoperative pediatric cerebellar mutism syndrome using arterial spin labeling perfusion MRI by Jennifer Boisgontier, Ludovic Fillon, Caroline Rutten, Ana Saitovitch, Christelle Dufour, Hervé Lemaître, Kévin Beccaria, Thomas Blauwblomme, Raphaël Levy, Volodia Dangouloff-Ros, David Grévent, Charles-Joris Roux, Jacques Grill, Alice Vinçon-Leite, Lila Saidoun, Franck Bourdeaut, Monica Zilbovicius, Nathalie Boddaert and Stéphanie Puget in Journal of Cerebral Blood Flow & Metabolism
Review of #SuchStuff Podcast by the London Globe, Early Modern Digital Review 6.2 (2023): 149-153
Creators: name: Joubin, Alexa Alice
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Podcasts
subject: Shakespeare, William, 1564-1616
subject: Feminism
subject: Critical race theory
subject: Education
subject: Digital humanities

description: Educational podcasts have gained momentum in recent years. Closure of live performance venues and widespread lockdowns as part of public hygiene measures during the global COVID-19 pandemic further increased interest in at-home consumption of digitally delivered content for entertainment and education. Supported by the Globe Theatre’s education department, the #SuchStuff podcast offers thematic dialogues that can be categorized as a “conversationalist chat show.” Listeners and podcasters meeting in digital space may be “such stuff as dreams are made on,” but the important topics of social justice covered by this series will not melt into thin air.
Influenza vaccine effectiveness against medically-attended influenza infection in 2023/24 season in Hangzhou, China
Creators: name: Lei, Hao
name: Niu, Beidi
name: Sun, Zhou
name: Wang, Yaojing
name: Che, Xinren
name: Du, Shengqiang
name: Liu, Yan
name: Zhang, Ke
name: Zhao, Shi
name: Yang, Shigui
name: Wang, Zhe
name: Zhao, Gang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: From 2020, influenza viruses circulation was largely affected by the global coronavirus disease (COVID-19) pandemic, notably leading to the extinction of the B/Yamagata lineage and raising questions about the relevance of the quadrivalent influenza vaccine, which includes this lineage. Evaluating vaccine effectiveness (VE) against influenza infections is important to inform future vaccine programs. A test-negative case–control study was conducted in five tertiary hospitals in Hangzhou, the capital city of Zhejiang province, China, enrolling medically-attended patients aged >6 months who presented with influenza-like illness (ILI) from October 1, 2023, to March 31, 2024. The VE was estimated using multivariate logistic regression models adjusted for sex, age, influenza detection methods, and influenza testing timing. Of the 157,291 medically-attended ILI participants enrolled 56,704 (36%) tested positive for influenza. Adjusted overall VE against any medically-attended influenza infection was 48% (95% Confidence interval [CI]: 46%–51%). The overall VE of the trivalent inactivated influenza vaccine (IIV3) was 59% (95% CI: 50%–66%), followed by the trivalent live attenuated vaccine (LAIV3) (VE = 53%, 95% CI: 42%–62%) and quadrivalent inactivated influenza vaccine (IIV4) (VE = 47%, 95% CI: 45%–50%). IIV3 provided even better protection against medically-attended influenza B infection than IIV4 (VE = 87%, 95% CI: 81%–92% for IIV3 versus VE = 53%, 95% CI: 50%–57% for IIV4). In the 2023/24 season in Hangzhou, China, the influenza vaccine offered moderate protection during a major epidemic. The results supported the World Health Organization recommendation to exclude the B/Yamagata lineage antigen in quadrivalent influenza vaccines in 2023.
sj-docx-3-mmc-10.1177_20501579211028647 – Supplemental material for Digital detox: An effective solution in the smartphone era? A systematic literature review
Creators: name: Radtke, Theda
name: Apel, Theresa
name: Schenkel, Konstantin
name: Keller, Jan
name: von Lindern, Eike
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, sj-docx-3-mmc-10.1177_20501579211028647 for Digital detox: An effective solution in the smartphone era? A systematic literature review by Theda Radtke, Theresa Apel, Konstantin Schenkel, Jan Keller and Eike von Lindern in Mobile Media & Communication
sj-pdf-1-eep-10.1177_08883254211012770 – Supplemental material for Actions Speak Louder Than Words? The Untapped Potential of V4 Parliaments in EU Affairs
Creators: name: Borońska-Hryniewiecka, Karolina
name: Grinc, Jan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 120505 Regional Analysis and Development
subject: FOS: Social and economic geography

description: Supplemental material, sj-pdf-1-eep-10.1177_08883254211012770 for Actions Speak Louder Than Words? The Untapped Potential of V4 Parliaments in EU Affairs by Karolina Borońska-Hryniewiecka and Jan Grinc in East European Politics & Societies and Cultures
Additional file 8 of Integrated transcriptomic and metabolomic analyses reveals anthocyanin biosynthesis in leaf coloration of quinoa (Chenopodium quinoa Willd.)
Creators: name: Zhang, Min
name: Li, Yueyou
name: Wang, Junling
name: Shang, Shaopu
name: Wang, Hongxia
name: Yang, Xinlei
name: Lu, Chuan
name: Wang, Mei
name: Sun, Xinbo
name: Liu, Xiaoqing
name: Wang, Xiaoxia
name: Wei, Boxiang
name: Lv, Wei
name: Mu, Guojun
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 8
Efficient deep networks for real-world interaction
Creators: name: Chaurasia, Abhishek
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Digital processor architectures
Other information and computing sciences not elsewhere classified

description: Deep neural networks are essential in applications such as image categorization, natural language processing, autonomous driving, home automation, and robotics. Most of these applications require instantaneous processing of data and decision making. In general existing neural networks are computationally expensive, and hence they fail to perform in real-time. Models performing semantic segmentation are being extensively used in self-driving vehicles. Autonomous vehicles not only need segmented output, but also control system capable of processing segmented output and deciding actuator outputs such as speed and direction.
 In this thesis we propose efficient neural network architectures with fewer operations and parameters as compared to current state-of-the-art algorithms. Our work mainly focuses on designing deep neural network architectures for semantic segmentation. First, we introduce few network modules and concepts which help in reducing model complexity. Later on, we show that in terms of accuracy our proposed networks perform better or at least at par with state-of-the-art neural networks. Apart from that, we also compare our networks' performance on edge devices such as Nvidia TX1. Lastly, we present a control system capable of predicting steering angle and speed of a vehicle based on the neural network output.
DIY Feminism in Post-Industrial Spaces
Creators: name: Sherrill, John T
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Technical writing

description: Situating makerspaces as an extension of post-industrial economies, and sites where technical communication and craftivism take place, this dissertation builds on critiques of makerspaces as hobbyist spaces that privilege digital electronics, populated mostly by white men. To do so, this dissertation analyzes who participates in feminist makerspaces, how “makers” describe their work and their experiences, and the roles of rhetoric and technical communication within feminist makerspaces. Building on prior studies of maker communities, this research follows a mixed methods approach and an iterative methodology, including online survey, site studies, interviews, and on-site automated survey to collect user data via kiosk. The online survey asked participants to describe makerspaces they’ve visited, their experiences visiting makerspaces, their work, and themselves. Follow-up interviews conducted with three survey participants addressed times participants felt unwelcome or out of place in a makerspace. Additionally, site studies consisted of visiting and observing two Midwestern makerspaces, both of which partnered with public libraries. This dissertation argues that makerspaces need to do a better job of welcoming guests and new members and actively hosting social events, rather than passively marketing workshops focused on specific technologies. Although people are becoming more familiar with makerspaces, regardless of gender and other aspects of identity, participants describe social anxieties about entering new spaces and unfamiliar communities as common barriers to entry, even before encountering issues based on gender, race, and other aspects of identity. If makerspaces (and “maker” communities more broadly) aim to be more inclusive and equitable, then actively welcoming people in general is a necessary baseline. As such, this dissertation draws from rhetorical theory to suggest ways that makerspaces can improve their hospitality and technical communication practices.
HUMAN-INDUCED VERTICAL VIBRATION ON PEDESTRIAN STRUCTURES: NUMERICAL AND EXPERIMENTAL ASSESSMENT
Creators: name: Pizano, Daniel Gomez
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Dynamics, vibration and vibration control

description: In recent years civil engineering structures such as floors, footbridges, and staircases, have reported unacceptable vibration when they are dynamically excited by pedestrians. When such structures have a particular combination of high structural flexibility and low inherent damping, there is potential for excessive vibration. Pedestrian-structure interaction (PSI) is especially noticeable when the lowest structural natural frequencies are close to the dominant pedestrian pace frequency or its harmonics. Although most of these structures are designed according to existing standards and guidelines, there are still many uncertainties in the human actions that may lead to unexpected structural behavior, increasing the vibration responses and exceeding serviceability limit states. How a pedestrian excites a structure and how that structure affects a pedestrian's gait is not fully understood. Therefore, a realistic analysis of PSI must be performed to properly incorporate these effects toward more rational structural designs. This study aims to identify, within this class of the walking-induced load problem, the vibration mechanisms, the mathematical models, and methods, to address excessive vibration in pedestrian structures. After conducting an in-depth evaluation of current guidelines and provisions for analysis and design of pedestrian structures, models to enable more realistic design under such uncertainties have been developed. The results establish a body of knowledge regarding human loads and structural responses, yielding the potential for more rational approaches to improve the analysis and design of pedestrian structures.
Additional file 1 of Germline variants in the Von Hippel-Lindau tumor suppressor gene in Cuban patients
Creators: name: Esperón Álvarez, Antonio Alejandro
name: Noa Hechavarría, Inés Virginia
name: López Reyes, Ixchel
name: Collazo Mesa, Teresa
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure 1 Pedigree of family 1 where the R161X (c.481C > T) mutation is being segregated (VHL Type 1). Figure 2 Pedigree of family 2 where the D121G (c.362A > G) mutation is being segregated (VHL Type 2). Figure 3 Pedigree of family 3 where the D121G (c.362A > G) mutation is being segregated (VHL Type 2). Figure 4 Pedigree of family 4 where the S183X (c.548C > A) mutation is being segregated (VHL Type 1). Figure 5 Pedigree of family 5 where the c.463+2T > C mutation is being segregated (VHL Type 2). Figure 6 Pedigree of family 6 where the R167W (c.499C > T) mutation is being segregated (VHL Type 2). Figure 7 Pedigree of family 7 where the C162W (c.486C > G) mutation is being segregated (VHL Type 1).
The efficacy and safety of rituximab monotherapy in the new onset pediatric idiopathic nephrotic syndrome: a randomized controlled clinical trial
Creators: name: Sheng, Ai-Qin
name: Liu, Fei
name: Li, Qiu-Yu
name: Dou, Ya-Lan
name: Zhang, Xiao-Jing
name: Zhao, Jing-Li
name: Huang, Ling-Fei
name: He, Si-Yi
name: Lu, Zhi-Hong
name: Feng, Chun-Yue
name: Wang, Jing-Jing
name: Shen, Hui-Jun
name: Fu, Hai-Dong
name: Yan, Wei-Li
name: Mao, Jian-Hua
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Nephrotic syndrome (NS) is a common form of glomerular disease in children, characterized by a high propensity for relapse. Prolonged use of glucocorticoids (GCs) can result in various side effects. Rituximab (RTX) may be considered as an initial treatment option for primary nephrotic syndrome in pediatric patients. We conducted a prospective, single-center, randomized controlled trial (RCT) to evaluate whether the initial use of RTX monotherapy is superior to GC therapy in treating pediatric idiopathic NS and to assess its safety. The primary outcome and secondary outcomes were compared between the two groups. A total of 24 pediatric patients were included in the study, comprising 19 males and 5 females. After six weeks of treatment, the complete remission (CR) rate in the GC group was significantly higher than that in the RTX group (100% vs 33.3%). Compared with the RTX group, the GC group had a shorter time to first remission (14.25 d vs. 9.5 d). During the follow-up period, none of the patients in the RTX group who achieved CR experienced relapse, with the longest relapse-free duration being 79 weeks. In the GC group, nine patients experienced relapse with the longest relapse-free period being 94 weeks. No serious adverse events occurred in either group. The cumulative steroid dosage was not statistically different between the 2 groups (p = 0.41). Although the CR rate of children with idiopathic NS treated with RTX alone is significantly lower, the relapse rate among responders to RTX is also lower than that of the GC treatment.
MULTI-LEVEL REGULATION OF T HELPER CELLS BY RETINOIC ACID RECEPTOR ALPHA
Creators: name: Friesen, Leon R
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Immunology not elsewhere classified

description: The active metabolite of vitamin A, retinoic acid, is a key mediator of balanced immune responses. The major nuclear receptor of retinoic acid, retinoic receptor alpha (RARα), functions as a transcriptional regulator, with both active and repressive effects on transcription depending on interactions with nuclear cofactors dictated by ligand-binding effects on protein confirmation. While significant advances have been made in understanding the combined effects of retinoic acid and RARα, the individual roles of each remain incompletely identified. Epigenetic effects of all-trans retinoic acid (At-RA) and RARα on the transcriptome of T helper cells were assessed using a novel transgenic mouse strain designed to overexpress RARα in T cells and a conditional knock out strain in which RARα was specifically deleted from T cells. At-RA and RARα had divergent roles in promoting Th17 and Treg differentiation, with RARα expression favoring Th17 differentiation over Treg differentiation, and At-RA promoting Treg differentiation over Th17 differentiation. Transcriptome analysis identified groups of At-RA and RARα differentially regulated genes (DEGs). Comparison of these genes to the H3k27 acetylated and tri-methylated epigenetic modifications demonstrated that RARα expression increased the overall level of these epigenetic modifications in all DEG groups, with enhanced control of transcriptional regulation mediated by higher RARα expression. Additionally, expression of transcriptional repressors was strongly regulated by At-RA in a RARα-dependent manner and had repressive effects on the differentiation of T helper cells. Immunometabolism was also enhanced by RARα expression, leading us to study potential non-genomic roles of RARα on signaling pathways. The major TCR signaling pathways were enhanced by RARα but suppressed by At-RA, suggesting a mechanism by which RARα regulates cellular metabolism upon T cell activation. In summary, we identified distinct epigenetic and non-genomic effects of RARα as novel regulatory mechanisms by which vitamin A and retinoic acid influence immune responses. Further research into these findings, notably RARα involvement in signal transduction pathways of immune cells, will define how this research can be translated into clinically-relevant applications.
sj-pdf-1-eqs-10.1177_87552930211018723 – Supplemental material for NGA-East Ground-Motion Characterization modelpart I: Summary of products and model development
Creators: name: Goulet, Christine A
name: Bozorgnia, Yousef
name: Kuehn, Nicolas
name: Al Atik, Linda
name: Youngs, Robert R
name: Graves, Robert W
name: Atkinson, Gail M
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental material, sj-pdf-1-eqs-10.1177_87552930211018723 for NGA-East Ground-Motion Characterization modelpart I: Summary of products and model development by Christine A Goulet, Yousef Bozorgnia, Nicolas Kuehn, Linda Al Atik, Robert R Youngs, Robert W Graves and Gail M Atkinson in Earthquake Spectra
Socioeconomic disparities in childhood vaccine hesitancy among parents in China: The mediating role of social support and health literacy
Creators: name: Yao, Xuelin
name: Fu, Mao
name: Peng, Jin
name: Feng, Da
name: Ma, Yue
name: Wu, Yifan
name: Feng, Liuxin
name: Fang, Yu
name: Jiang, Minghuan
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Molecular Biology
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Parental vaccine hesitancy is a major obstacle to childhood vaccination. We examined parental socioeconomic status (SES) disparities in vaccine hesitancy, and the potential mediating roles of perceived social support and health literacy. A questionnaire survey was given to parents with children aged below 6 years from six provinces in China. SES was examined by educational attainment, annual household income, and a subjective measure of SES (using a scale of 1–10). Linear regression was applied to assess the association between SES and vaccine hesitancy. Bootstrapping mediation analysis was performed with 5,000 samples bootstrapped. A total of 1,638 parents were included. Using annual household income > 200,000 Chinese yuan (CNY) as a reference, parents with lower household income (CNY 100,001–150,000) experienced higher vaccine hesitancy. Educational attainment was not associated with vaccine hesitancy. Subjective SES had a U-shaped relationship with vaccine hesitancy. Perceived social support and health literacy independently and sequentially mediated the effects of subjective SES (indirect effect: −0.240) and annual household income (indirect effect: 1.250 for ≤ CNY 100,000 and 0.759 for CNY 100,001–150,000) on vaccine hesitancy. Socioeconomic disparities influenced parental vaccine hesitancy in China, which were mediated by perceptions of social support and health literacy.
Smoking as a causative factor in chronic kidney disease: a two-sample Mendelian randomization study
Creators: name: Yang, Yue
name: Zhang, Zheng
name: Lu, Hai-tao
name: Xu, Qian-qian
name: Zhuo, Li
name: Li, Wen-ge
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: Smoking is widely acknowledged for its harmful effects on multiple organs. However, its specific causal relationship with chronic kidney disease (CKD) remains uncertain. This study applied bivariate causal analysis and two-sample Mendelian randomization (MR) methods to examine the association between various smoking behaviors – initiation, cessation, age at initiation, cigarettes smoked per day, and lifetime smoking – and CKD, using genome-wide data. The inverse variance weighted (IVW) method was the primary analytical tool, supported by sensitivity analyses, pleiotropy assessments, and mediation analyses. External validation was conducted using independent datasets. The results revealed positive associations between CKD and smoking initiation (Pivw = 1.8 × 10−2, OR = 1.192), earlier age at initiation (Pivw = 2.3 × 10−3, OR = 1.481), cigarettes smoked per day (Pivw = 8.8 × 10−3, OR = 1.216), and lifetime smoking (Pivw = 2.3 × 10−7, OR = 2.445). In contrast, smoking cessation demonstrated a protective effect against CKD (Pivw = 4.0 × 10−12, OR = 0.791). External validation results aligned with the primary findings, and the absence of significant heterogeneity confirmed the robustness of the MR analysis. Additionally, the effect of smoking on CKD was mediated by factors such as body mass index, cardiovascular disease, hypertension, and type 2 diabetes. These findings identify smoking as a contributing factor to CKD and suggest that reducing smoking prevalence could significantly lower the incidence of CKD in the population.
sj-pdf-1-gpi-10.1177_13684302211016047 – Supplemental material for “Nudging” intergroup contact: Normative social influences on intergroup contact engagement
Creators: name: Meleady, Rose
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-1-gpi-10.1177_13684302211016047 for “Nudging” intergroup contact: Normative social influences on intergroup contact engagement by Rose Meleady in Group Processes & Intergroup Relations
Mapping Whiteness: Uncovering the Legacy of All-White Towns in Indiana
Creators: name: Sdunzik, Jennifer
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Anthropology not elsewhere classified
Historical studies not elsewhere classified

description: Why did black southern migrants during the Great Migration not get off the train along the migratory corridor that connected the points of departure and arrival, i.e. the Jim Crow South and the urban North? How did midwestern small-towns and black America come to be understood as polar opposites? Based on archival and ethnographic research, this project answers these questions by disrupting grand narratives about the Great Migration and the Midwest: 1) it disrupts the idea of predefined destinations of southern black migrants by illustrating that not all wanted to settle in big cities; 2) it disrupts the midwestern whiteness by displaying resilience and resistance of minorities in the same landscape; and 3) it disrupts stereotypes of midwestern friendliness by uncovering the self-perceived understanding of midwestern hospitality of Hoosier communities that stands in stark contrast with the unwelcoming environment as experienced by outsiders. Together, the chapters in this dissertation record the racialized geographies of Indiana and provide a nuanced understanding of identity and belonging in the Midwest. Analysis of the data identifies cultures of exclusion prevalent in midwestern small towns.
Supplementary data: Optimizing Contextonym Analysis for Terminological Definition Writing
Creators: name: San Martín, Antonio
Publisher: name: Zenodo
Year: 2025

description: This is a list of the sources of the definitions used in the following article: San Martín A. "Optimizing Contextonym Analysis for Terminological Definition Writing". Information. 2025; 16(4). https://doi.org/10.3390/info16040257
Renal impairment and in-hospital adverse renal events in critically ill patients assessed by age-adapted estimated glomerular filtration rate criteria
Creators: name: Zhang, Chong
name: Liang, Weiru
name: Ning, Meng
name: Su, Bin
name: Guo, Tingting
name: Hu, Kun
name: Su, Wei
name: Chen, Yi
name: Peng, Wenjin
name: Liu, Yingwu
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer

description: Impaired renal function (IRF) is associated with an elevated risk of major adverse renal events (MARE). However, the relationship between age-adapted estimated glomerular filtration rate (eGFR) criteria and in-hospital MARE has not been extensively studied in critically ill patients. Furthermore, the impact of eGFR trajectory changes on in-hospital MARE in this patient population remains underexplored. In this study, we analyzed data from 7,423 critically ill patients using version 2.2 of the Medical Information Mart for Intensive Care IV database. Based on the age-adapted eGFR criteria, renal function status was classified as impaired renal function (IRF), subclinical impairment of renal function (SIRF), and normal renal function (NRF). There were 2,438 patients (32.8%) of in-hospital MARE. The incidence of MARE and their individual endpoint components was higher in patients with SIRF and IRF than in patients with NRF. Group-based trajectory modeling revealed that, compared with patients with other renal function status, patients with SIRF demonstrated the most significant decline in eGFR as well as the highest risk of MARE based on the results of the low-level-to-decline trajectory. Additionally, a trend toward an increased risk of MARE was observed in patients with SIRF and IRF, particularly among younger patients, when compared with those with NRF. Critically ill patients with SIRF and IRF had an increased risk of in-hospital MARE. Patients with SIRF experienced the most notable decline in renal function during hospitalization, with the highest risk of MARE noted in this trajectory group. In addition, a trend toward an increased risk of MARE was observed in younger patients. Consequently, active monitoring and timely intervention in younger patients are imperative.
Respiratory syncytial virus immunization with nirsevimab: Acceptance and satisfaction assessment in infants and risk groups in the region of Murcia (Spain)
Creators: name: Martín, Jaime Jesús Pérez
name: de la Cruz Gómez Moreno, María
name: Manresa, Susana Sánchez
name: del Pilar Ros Abellán, María
name: Zornoza-Moreno, Matilde
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Respiratory syncytial virus (RSV) is a leading cause of respiratory infections in infants under two years of age, often resulting in bronchiolitis and pneumonia, which contribute to high hospitalization rates. The recent approval of nirsevimab, a long-acting monoclonal antibody, has provided an immunization alternative for infants, addressing the substantial burden of RSV. This study aimed to evaluate acceptance and satisfaction among parents or legal guardians of infants who were candidates for immunization with nirsevimab in the Region of Murcia (Spain) during the 2023–2024 campaign. A cross-sectional survey, encompassing 1692 parents of immunized infants and 219 of non-immunized infants, revealed a high acceptance rate for nirsevimab, with 87% of parents indicating willingness to immunize a future child and 86.6% willing to recommend it. Concerns about safety and side effects were the primary reasons for hesitation among parents who did not immunize their infants. These findings underscore the importance of enhancing educational efforts in future campaigns to address safety concerns, thereby supporting broader RSV immunization coverage in the pediatric population.
sj-docx-1-car-10.1177_19476035211025817 – Supplemental material for Differential Contribution of the Medial and the Lateral Side of the Joint to Symptoms in Knee Osteoarthritis: A Radiographic and Laboratory Analysis in the Nagahama Study
Creators: name: Nigoro, Kazuya
name: Ito, Hiromu
name: Kawata, Tomotoshi
name: Ishie, Shinichiro
name: Morita, Yugo
name: Nishitani, Kohei
name: Aoyama, Tomoki
name: Tabara, Yasuharu
name: Matsuda, Fumihiko
name: Narumiya, Shu
name: Matsuda, Shuichi
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Supplemental material, sj-docx-1-car-10.1177_19476035211025817 for Differential Contribution of the Medial and the Lateral Side of the Joint to Symptoms in Knee Osteoarthritis: A Radiographic and Laboratory Analysis in the Nagahama Study by Kazuya Nigoro, Hiromu Ito, Tomotoshi Kawata, Shinichiro Ishie, Yugo Morita, Kohei Nishitani, Tomoki Aoyama, Yasuharu Tabara, Fumihiko Matsuda, Shu Narumiya and Shuichi Matsuda in CARTILAGE