cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
قوس معماری ایرانی-اسلامی در مفتاح الحساب غیاث الدین جمشید کاشانی
Creators: name: Kheiri, Ali
Publisher: name: figshare
Year: 2020
Subjects: subject: 120101 Architectural Design
subject: FOS: Arts (arts, history of arts, performing arts, music)
subject: 120102 Architectural Heritage and Conservation
subject: FOS: Civil engineering
subject: 120103 Architectural History and Theory
subject: 120104 Architectural Science and Technology (incl. Acoustics, Lighting, Structure and Ecologically Sustainable Design)
subject: 120105 Architecture Management
subject: 120199 Architecture not elsewhere classified
subject: 120301 Design History and Theory
subject: 120502 History and Theory of the Built Environment (excl. Architecture)
subject: FOS: Social and economic geography
subject: Geometry

description: در برخی از کتاب های محققان نامی غرب مانند کتاب (معماری ایلخانان) تألیف ( ویلبر) ، از منابع کتب قدیمی ایران ، ذکری به میان آمده که در مورد شکل قوس ها و طرز ترسیم آن ها سخن رانده است . این کتاب (مفتاح الحساب) نام دارد و از نوشته های دانشمند نامی و ریاضی دان ایران در قرن 9 هجری ، (غیاث الدین جمشید کاشانی) می باشد . مطالعه و بررسی این کتاب که یکی از کتاب های ریاضی مهمّ و مورد استفاده بزرگان ریاضی بوده و هست ، نشان می دهد که کاشانی در مبحث هندسه ، پس از ذکر مساحت اشکال مختلف هندسی و موارد استفاده آن ها قسمتی را هم به مساحات ابنیه و عمارات اختصاص داده است. کاشانی در این باب نخست به طرز کشیدن قوس ها که یکی از مبانی مهمّ معماری است اشاره کرده و سپس راه محاسبه سطوح مختلف آن را بیان داشته است. با دستیابی به این مدرک مهمّ و اصیل ، به شناخت و ترسیم قوس معماری ایرانی اسلامی می پردازیم.
One and two spin$-1/2$ particles systems under Lorentz transformations
Creators: name: Moradpour, H.
name: Bahadoran, M.
name: Ghasemi, A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Lorentz transformation (LT) is used to connect two inertia frames, including the lab and moving frames, and the effect of LT on the states of one spin-1/2 particle system is studied. Moreover, we address the predictions made by Czachor's and the Pauli spin operators about the spin behavior and compare our results with the behavior of system's state under Lorentz transformation. This investigation shows that the predictions made by considering the Pauli spin operator about the spin of system are in better agreement with the system's state in comparison with that of made by considering Czachor's spin operator. In continue, we focus on two-particle pure entangled systems including two spin$-1/2$ particles which moves away from each other. Once again, the behavior of this system's states under Lorentz transformation are investigated. We also point to the behavior of Bell's inequality, as a witness for non-locality, under Lorentz transformation. Our study shows that the Bell operator made by the Pauli operator has better consistency with the behavior of spin state of system under Lorentz transformation compared with the Bell operator made by Czachor's operator. Our approach can be used to study the relation between the various spin operators and the effect of LT on system, which provides the basement to predict the outcome of a Stern-Gerlach type experiment in the relativistic situations.
description: The text have been revised and one figure was added
Composition constraints of the TRAPPIST-1 planets from their formation
Creators: name: Childs, Anna C.
name: Shakespeare, Cody
name: Rice, David R.
name: Yang, Chao-Chin
name: Steffen, Jason H.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We study the formation of the TRAPPIST-1 (T1) planets starting shortly after Moon-sized bodies form just exterior to the ice line. Our model includes mass growth from pebble accretion and mergers, fragmentation, type-I migration, and eccentricity and inclination dampening from gas drag. We follow the composition evolution of the planets fed by a dust condensation code that tracks how various dust species condense out of the disc as it cools. We use the final planet compositions to calculate the resulting radii of the planets using a new planet interior structure code and explore various interior structure models. Our model reproduces the broader architecture of the T1 system and constrains the initial water mass fraction of the early embryos and the final relative abundances of the major refractory elements. We find that the inner two planets likely experienced giant impacts and fragments from collisions between planetary embryos often seed the small planets that subsequently grow through pebble accretion. Using our composition constraints we find solutions for a two-layer model, a planet comprised of only a core and mantle, that match observed bulk densities for the two inner planets b and c. This, along with the high number of giant impacts the inner planets experienced, is consistent with recent observations that these planets are likely dessicated. However, two-layer models seem unlikely for most of the remaining outer planets which suggests that these planets have a primordial hydrosphere. Our composition constraints also indicate that no planets are consistent with a core-free interior structure.
description: 15 pages, 8 figures, 4 tables, and an appendix. Accepted for publication in MNRAS
Taming the degeneration of Bessel beams at anisotropic-isotropic interface: toward 3D control of confined vortical waves
Creators: name: Riaud, Antoine
name: Thomas, Jean-Louis
name: Baudoin, Michael
name: Matar, Olivier Bou
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Despite their self-reconstruction properties in heterogeneous media, Bessel beams are known to degenerate when they are refracted from an isotropic to an anisotropic medium. In this paper, we study the converse situation wherein an anisotropic Bessel beam is refracted into an isotropic medium. It is shown that these anisotropic Bessel beams also degenerate, leading to confined vortical waves that may serve as localized particle trap for acoustical tweezers. The linear nature of this degeneration allows the 3D control of this trap position by wavefront correction. Theory is confronted to experiments performed in the field of acoustics. A swirling surface acoustic wave is synthesized at the surface of a piezoelectric crystal by a MEMS integrated system and radiated inside a miniature liquid vessel. The wavefront correction is operated with inverse filter technique. This work opens perspectives for contactless on-chip manipulation devices.
A helium nova in the Large Magellanic Cloud -- the faint supersoft X-ray source [HP99]159
Creators: name: Kato, Mariko
name: Hachisu, Izumi
name: Saio, Hideyuki
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We propose a helium nova model for the Large Magellanic Cloud (LMC) supersoft X-ray source (SSS) [HP99]159. This object has long been detected as a faint and persistent SSS for about 30 years, and recently been interpreted to be a source of steady helium-shell burning, because no hydrogen lines are observed. We find that the object can also be interpreted as in a decaying phase of a helium nova. The helium nova is slowly decaying toward the quiescent phase, during which the observed temperature, luminosity, and SSS lifetime ($\gtrsim 30$ years) are consistent with a massive white dwarf model of $\sim$ 1.2 $M_\odot$. If it is the case, this is the second discovery of a helium nova outburst after V445 Pup in our Galaxy and also the first identified helium nova in the LMC. We also discuss the nature of the companion helium star in relation to Type Ia supernova progenitors.
description: 4 pages, 4 figures, accepted in MNRAS (Letters)
Antitumor agents 278. 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs as potent in vitro anti-cancer agents
Creators: name: Dong, Yizhou
name: Lee, Kuo Hsiung
name: Morris-Natschke, Susan L.
name: Lai, Chin Yu
name: Nakagawa-Goto, Kyoko
name: Bastow, Kenneth F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs were designed, synthesized, and evaluated for cytotoxic activity. Among all 4-substituted ABO analogs, cyclohexyl (12), N-methoxy-N-methylacetamide (14), and various aromatic derivatives (15-25 and 27) exhibited promising cell growth inhibitory activity with ED50 values of 0.01-2.1 μM against all tested tumor cell lines. The 4′-methoxyphenyl derivative (18) and 3′-methylphenyl derivative (24) showed the most potent antitumor activity against a broad range of cancer cell lines with ED50 values of 0.01-0.17 μM. Preliminary SAR results indicated that substitutions on nitrogen are critical to the antitumor potency.
قوس معماری ایرانی - اسلامی در مفتاح الحساب غیاث‌الدین
Creators: name: Kheiri, Ali
Publisher: name: figshare
Year: 2020
Subjects: subject: 120101 Architectural Design
subject: FOS: Arts (arts, history of arts, performing arts, music)
subject: 120102 Architectural Heritage and Conservation
subject: FOS: Civil engineering
subject: 120103 Architectural History and Theory
subject: 120104 Architectural Science and Technology (incl. Acoustics, Lighting, Structure and Ecologically Sustainable Design)
subject: 120105 Architecture Management
subject: 120199 Architecture not elsewhere classified
subject: 120301 Design History and Theory
subject: 120502 History and Theory of the Built Environment (excl. Architecture)
subject: FOS: Social and economic geography
subject: Geometry

description: در برخی از کتاب های محققان نامی غرب مانند کتاب (معماری ایلخانان) تألیف ( ویلبر) ، از منابع کتب قدیمی ایران ، ذکری به میان آمده که در مورد شکل قوس ها و طرز ترسیم آن ها سخن رانده است . این کتاب (مفتاح الحساب) نام دارد و از نوشته های دانشمند نامی و ریاضی دان ایران در قرن 9 هجری ، (غیاث الدین جمشید کاشانی) می باشد . مطالعه و بررسی این کتاب که یکی از کتاب های ریاضی مهمّ و مورد استفاده بزرگان ریاضی بوده و هست ، نشان می دهد که کاشانی در مبحث هندسه ، پس از ذکر مساحت اشکال مختلف هندسی و موارد استفاده آن ها قسمتی را هم به مساحات ابنیه و عمارات اختصاص داده است. کاشانی در این باب نخست به طرز کشیدن قوس ها که یکی از مبانی مهمّ معماری است اشاره کرده و سپس راه محاسبه سطوح مختلف آن را بیان داشته است. با دستیابی به این مدرک مهمّ و اصیل ، به شناخت و ترسیم قوس معماری ایرانی اسلامی می پردازیم.
Antitumor agents. 271: Total synthesis and evaluation of brazilein and analogs as anti-inflammatory and cytotoxic agents
Creators: name: Morris-Natschke, Susan L.
name: Chang, Fang Rong
name: Yen, Chiao Ting
name: Hwang, Tsong Long
name: Wu, Pei Chi
name: Lee, Kuo Hsiung
name: Lai, Wan Chun
name: Wu, Yang Chang
name: Bastow, Kenneth F.
name: Nakagawa-Goto, Kyoko
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The first total synthesis of the naturally occurring tetracyclic homoisoflavonoid brazilein (1) and 14 new analogs (1a–n) is reported. Target compounds and intermediates were assayed for anti-inflammatory effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB, and for cytotoxic activity against nasopharyngeal (KB), vincristine-resistant nasopharyngeal (KBvin), lung (A549) and prostate (DU-145) human cancer cell lines. The most active compound 1b showed potent effects on superoxide anion generation and elastase release with IC50 values of 1.2 and 1.9 µM, respectively, and was 65 times more potent than phenylmethylsulfonyl fluoride (PMSF), the positive control, in the latter assay. Additionally, 1b exhibited broad spectrum in vitro anticancer activity with IC50 values of 6–11 µM against the four tested cancer cell lines.
Synthesis and anti-HIV activity of 2′-deoxy-2′-fluoro-4′-C-ethynyl nucleoside analogs
Creators: name: Chang, Junbiao
name: Qian, Keduo
name: Lee, Kuo Hsiung
name: Wang, Qiang
name: Li, Yanfeng
name: Chen, Chin Ho
name: Song, Chuanjun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Based on the favorable antiviral profiles of 4′-substituted nucleosides, novel 1-(2′-deoxy-2′-fluoro-4′-C-ethynyl-β-D-arabinofuranosyl)-uracil (1a), -thymine (1b), and – cytosine (2) analogues were synthesized. Compounds 1b and 2 exhibited potent anti-HIV-1 activity with IC50 values of 86 and 1.34 nM, respectively, without significant cytotoxicity. Compound 2 was 35-fold more potent than AZT against wild-type virus, and also retained nanomolar antiviral activity against resistant strains, NL4-3(K101E) and RTMDR. Thus, 2 merits further development as a novel NRTI drug.
Log-unimodality for free positive multiplicative Brownian motion
Creators: name: Hasebe, Takahiro
name: Ueda, Yuki
name: Wang, Jiun-Chau
Publisher: name: arXiv
Year: 2020
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 46L54, 60J65, 60E07, 60B15

description: We prove that the marginal law $σ_{t}\boxtimesν$ of free positive multiplicative Brownian motion is log-unimodal for all $t>0$ if $ν$ is a multiplicatively symmetric log-unimodal distribution, and that $σ_{t}\boxtimesν$ is log-unimodal for sufficiently large $t$ if $ν$ is supported on a suitably chosen finite interval. Counterexamples are given when $ν$ is not assumed to be symmetric or having a bounded support.
description: 14 pages
(102876) Sarah Ann Warren
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Antitumor agents 279. Structure–activity relationship and in vivo studies of novel 2-(furan-2-yl)naphthalen-1-ol (FNO) analogs as potent and selective anti-breast cancer agents
Creators: name: Bastow, Kenneth F.
name: Lee, Eva Y.H.P.
name: Morris-Natschke, Susan L.
name: Nakagawa-Goto, Kyoko
name: Dong, Yizhou
name: Lee, Kuo Hsiung
name: Kim, Yoon
name: Lai, Chin Yu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: In our ongoing modification study of neo-tanshinlactone (1), we discovered 2-(furan-2-yl)naphthalen-1-ol (FNO) derivatives 3 and 4 as a new class of anti-tumor agents. To explore structure-activity relationships (SAR) of this scaffold, 18 new analogs, 6–12 and 14–24, were designed and synthesized. The C11-esters 7 and 12 displayed broad anti-tumor activity (ED50 1.1–4.3 µg/mL against seven cancer cell lines), while C11-hydroxymethyl 14 showed unique selectivity against the SKBR-3 breast cancer cell line (ED50 0.73 µg/mL). Compounds 15 and 22 displayed potent and selective anti-breast tumor activity (ED50 1.7 and 0.85 µg/mL, respectively, against MDA-MB-231). The SAR results demonstrated that the substitutions from the ring-opened lactone ring C of 1 are critical to the anti-tumor potency as well as the apparent tumor-tissue type selectivity. Treatment with 3 in Brca1f11/f11p53f5&6/f5&6Crec mice models significantly inhibited the proliferation of mammary epithelial cells and branching of mammary glands.
Intrinsic limits to gene regulation by global crosstalk
Creators: name: Friedlander, Tamar
name: Prizak, Roshan
name: Guet, Călin C.
name: Barton, Nicholas H.
name: Tkačik, Gašper
Publisher: name: arXiv
Year: 2015
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Gene regulation relies on the specificity of transcription factor (TF) - DNA interactions. In equilibrium, limited specificity may lead to crosstalk: a regulatory state in which a gene is either incorrectly activated due to noncognate TF-DNA interactions or remains erroneously inactive. We present a tractable biophysical model of global crosstalk, where many genes are simultaneously regulated by many TFs. We show that in the simplest regulatory scenario, a lower bound on crosstalk severity can be analytically derived solely from the number of (co)regulated genes and a suitable parameter that describes binding site similarity. Estimates show that crosstalk could present a significant challenge for organisms with low-specificity TFs, such as metazoans, unless they use appropriate regulation schemes. Strong cooperativity substantially decreases crosstalk, while joint regulation by activators and repressors, surprisingly, does not; moreover, certain microscopic details about promoter architecture emerge as globally important determinants of crosstalk strength. Our results suggest that crosstalk imposes a new type of global constraint on the functioning and evolution of regulatory networks, which is qualitatively distinct from the known constraints acting at the level of individual gene regulatory elements.
Antitumor agents 281. Design, synthesis, and biological activity of substituted 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one analogs (ATBO) as potent in vitro anticancer agents
Creators: name: Dong, Yizhou
name: Lai, Chin Yu
name: Bastow, Kenneth F.
name: Lee, Kuo Hsiung
name: Morris-Natschke, Susan L.
name: Nakagawa-Goto, Kyoko
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: In our exploration of new biologically active chemical entities, we designed and synthesized a novel class of antitumor agents, substituted 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one (ATBO) analogs. We evaluated their cytotoxic activity against seven human tumor cell lines from different tissues, and established preliminary structure-activity relationships (SAR). All analogues, except 8, 9, and 25-27, displayed potent tumor cell growth inhibitory activity. Especially, compounds 15 and 33 with a 4-methoxyphenyl group at position C-4 were extremely potent with ED50 values of 0.008-0.064 μM and 0.035-0.32 μM, respectively. Compound 15 was the most potent analog compared with structurally related neo-tanshinlactone (e.g., 1) and 4-amino-2H-benzo[h]chromen-2-one (ABO, e.g., 4) analogs, and thus merits further exploration as an anti-cancer drug candidate.
PSweight: An R Package for Propensity Score Weighting Analysis
Creators: name: Zhou, Tianhui
name: Tong, Guangyu
name: Li, Fan
name: Thomas, Laine E.
name: Li, Fan
Publisher: name: arXiv
Year: 2020
Subjects: subject: Methodology (stat.ME)
subject: Computation (stat.CO)
subject: FOS: Computer and information sciences

description: Propensity score weighting is an important tool for comparative effectiveness research.Besides the inverse probability of treatment weights (IPW), recent development has introduced a general class of balancing weights, corresponding to alternative target populations and estimands. In particular, the overlap weights (OW) lead to optimal covariate balance and estimation efficiency, and a target population of scientific and policy interest. We develop the R package PSweight to provide a comprehensive design and analysis platform for causal inference based on propensity score weighting. PSweight supports (i) a variety of balancing weights, (ii) binary and multiple treatments,(iii) simple and augmented weighting estimators, (iv) nuisance-adjusted sandwich variances, and(v) ratio estimands. PSweight also provides diagnostic tables and graphs for covariate balance assessment. We demonstrate the functionality of the package using a data example from the NationalChild Development Survey (NCDS), where we evaluate the causal effect of educational attainment on income.
description: 18 pages, 3 figures, 5 tables
exploiting-remote-communication-to-conduct-a-minicourse-for-architectural-graduation-projects-jury-simulation-629c2b1f91642-1.pdf
Creators: name: Desouki, Mahmoud
name: Alzahrani, Abdullah Mossa Y.
name: Aly, Reda M. H.
name: Elboshy, Bahaa
Publisher: name: figshare
Year: 2023
Subjects: Other engineering not elsewhere classified
Agricultural engineering
Architectural design

description: Graduation project architectural jury is the most crucial event in the life ofthe architecture student. Therefore, students are keen to perform on this day as optimally as possible. In line with this, this study is concerned with the development of architectural design learning and aims to present a framework for teaching jury and design skills via remote communication using minicourses, as well as to investigate its impact on students’ performance. This empirical study was conducted in the summer vacation of 2020 during the COVID-19 lockdown and was examined through a structured questionnaire directed to students’ study content and a structured rubric of faculty jurors. The data garnered was analysed using descriptive and inferential statistics, the findings of which having the potential to develop the design teaching policies for Egyptian schools of architecture.Graduation project architectural jury is the most crucial event in the life ofthe architecture student. Therefore, students are keen to perform on this day as optimally as possible. In line with this, this study is concerned with the development of architectural design learning and aims to present a framework for teaching jury and design skills via remote communication using minicourses, as well as to investigate its impact on students’ performance. This empirical study was conducted in the summer vacation of 2020 during the COVID-19 lockdown and was examined through a structured questionnaire directed to students’ study content and a structured rubric of faculty jurors. The data garnered was analysed using descriptive and inferential statistics, the findings of which having the potential to develop the design teaching policies for Egyptian schools of architecture.
Poincare: Recommending Publication Venues via Treatment Effect Estimation
Creators: name: Sato, Ryoma
name: Yamada, Makoto
name: Kashima, Hisashi
Publisher: name: arXiv
Year: 2020
Subjects: subject: Digital Libraries (cs.DL)
subject: Information Retrieval (cs.IR)
subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Choosing a publication venue for an academic paper is a crucial step in the research process. However, in many cases, decisions are based solely on the experience of researchers, which often leads to suboptimal results. Although there exist venue recommender systems for academic papers, they recommend venues where the paper is expected to be published. In this study, we aim to recommend publication venues from a different perspective. We estimate the number of citations a paper will receive if the paper is published in each venue and recommend the venue where the paper has the most potential impact. However, there are two challenges to this task. First, a paper is published in only one venue, and thus, we cannot observe the number of citations the paper would receive if the paper were published in another venue. Secondly, the contents of a paper and the publication venue are not statistically independent; that is, there exist selection biases in choosing publication venues. In this paper, we formulate the venue recommendation problem as a treatment effect estimation problem. We use a bias correction method to estimate the potential impact of choosing a publication venue effectively and to recommend venues based on the potential impact of papers in each venue. We highlight the effectiveness of our method using paper data from computer science conferences.
description: Journal of Informetrics
p-exponent and p-leaders, Part II: Multifractal Analysis. Relations to Detrended Fluctuation Analysis
Creators: name: Leonarduzzi, Roberto
name: Wendt, Herwig
name: Abry, Patrice
name: Jaffard, Stéphane
name: Melot, Clothilde
name: Roux, Stéphane G.
name: Torres, Maria E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics

description: Multifractal analysis studies signals, functions, images or fields via the fluctuations of their local regularity along time or space, which capture crucial features of their temporal/spatial dynamics. It has become a standard signal and image processing tool and is commonly used in numerous applications of different natures. In its common formulation, it relies on the Hölder exponent as a measure of local regularity, which is by nature restricted to positive values and can hence be used for locally bounded functions only. In this contribution, it is proposed to replace the Hölder exponent with a collection of novel exponents for measuring local regularity, the $p$-exponents. One of the major virtues of $p$-exponents is that they can potentially take negative values. The corresponding wavelet-based multiscale quantities, the $p$-leaders, are constructed and shown to permit the definition of a new multifractal formalism, yielding an accurate practical estimation of the multifractal properties of real-world data. Moreover, theoretical and practical connections to and comparisons against another multifractal formalism, referred to as multifractal detrended fluctuation analysis, are achieved. The performance of the proposed $p$-leader multifractal formalism is studied and compared to previous formalisms using synthetic multifractal signals and images, illustrating its theoretical and practical benefits. The present contribution is complemented by a companion article studying in depth the theoretical properties of $p$-exponents and the rich classification of local singularities it permits.
(102875) James Cowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Nonlinear imaging of nanoscale topological corner states
Creators: name: Kruk, Sergey
name: Gao, Wenlong
name: Choi, Duk Yong
name: Zentgraf, Thomas
name: Zhang, Shuang
name: Kivshar, Yuri
Publisher: name: arXiv
Year: 2020
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Topological states of light represent counterintuitive optical modes localized at boundaries of finite-size optical structures that originate from the properties of the bulk. Being defined by bulk properties, such boundary states are insensitive to certain types of perturbations, thus naturally enhancing robustness of photonic circuitries. Conventionally, the N-dimensional bulk modes correspond to (N-1)-dimensional boundary states. The higher-order bulk-boundary correspondence relates N-dimensional bulk to boundary states with dimensionality reduced by more than 1. A special interest lies in miniaturization of such higher-order topological states to the nanoscale. Here, we realize nanoscale topological corner states in metasurfaces with C6-symmetric honeycomb lattices. We directly observe nanoscale topology-empowered edge and corner localizations of light and enhancement of light-matter interactions via a nonlinear imaging technique. Control of light at the nanoscale empowered by topology may facilitate miniaturization and on-chip integration of classical and quantum photonic devices.
(102874) Gladys Rosalind Cowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Purely antiferromagnetic frustrated Heisenberg model in spin ladder compound BaFe$_2$Se$_3$
Creators: name: A., Roll
name: S., Petit
name: A., Forget
name: D., Colson
name: A., Banerjee
name: P., Foury-Leylekian
name: V, Balédent
Publisher: name: arXiv
Year: 2023
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The spin dynamics in the block magnetic phase of the iron-based ladder compound \bfs\ has been studied by means of single crystal inelastic neutron scattering. Using linear spin wave theory and Monte-Carlo simulations, our analysis points to a magnetic Heisenberg model with effective frustrated antiferromagnetic couplings only, able to describe both the exotic block order and its dynamics. This new and purely antiferromagnetic picture offers a fruitful perspective to describe multiferroic properties but also understand the origin of the stripe-like magnetic instability observed under pressure as well as in other parent compounds with similar crystalline structure.
(102872) Charles Henry Leslie
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Homomorphisms relative to additive convolutions and max-convolutions: free, boolean and classical cases
Creators: name: Hasebe, Takahiro
name: Ueda, Yuki
Publisher: name: arXiv
Year: 2020
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 46L54, 60E07, 60G70

description: We introduce new homomorphisms relative to additive convolutions and max-convolutions in free, boolean and classical cases. Crucial roles are played by the limit distributions for free multiplicative law of large numbers.
description: 15 pages
Antitumor agents 287. Substituted 4-amino-2H-pyran-2-one (APO) analogs reveal a new scaffold from neo-tanshinlactone with in vitro anticancer activity
Creators: name: Bastow, Kenneth F.
name: Lee, Kuo Hsiung
name: Nakagawa-Goto, Kyoko
name: Lai, Chin Yu
name: Dong, Yizhou
name: Morris-Natschke, Susan L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: 4-Amino-2H-benzo[h]chromen-2-one (ABO) and 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one (ATBO) analogs were found to be significant in vitro anticancer agents in our previous research. Our continuing study has now discovered a new simplified (monocyclic rather than tricyclic) class of cytotoxic agents, 4-amino-2H-pyran-2-one (APO) analogs. By incorporating various substituents on the pyranone ring, we have established preliminary structure-activity relationships (SAR). Analogs 19, 20, 23, and 26–30 displayed significant tumor cell growth inhibitory activity in vitro. The most active compound 27 exhibited ED50 values of 0.059–0.090 μM.
Chirality-controlled spin scattering through quantum interference
Creators: name: van Ruitenbeek, Jan M.
name: Korytár, Richard
name: Evers, Ferdinand
Publisher: name: arXiv
Year: 2023
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Chirality-induced spin selectivity has been reported in many experiments, but a generally accepted theoretical explanation has not yet been proposed. Here, we introduce a simple model system of a straight cylindrical free-electron wire, containing a helical string of atomic scattering centers, with spin-orbit interaction. The advantage of this simple model is that it allows deriving analytical expressions for the spin scattering rates, such that the origin of the effect can be easily followed. We find that spin-selective scattering can be viewed as resulting from constructive interference of partial waves scattered by the spin-orbit terms. We demonstrate that forward scattering rates are independent of spin, while back scattering is spin dependent over wide windows of energy. Although the model does not represent the full details of electron transmission through chiral molecules, it clearly reveals a mechanism that could operate in chiral systems.
description: 7 pages, 4 figures
Efficient synthesis and biological evaluation of epiceanothic acid and related compounds
Creators: name: Lee, Kuo Hsiung
name: Zhang, Pu
name: Qian, Keduo
name: Liu, Jun
name: Sun, Hongbin
name: Xu, Li
name: Zhang, Luyong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Epiceanothic acid (1) is a naturally occurring, but very rare pentacyclic triterpene with a unique pentacyclic triterpene (PT) structure. An efficient synthesis of 1 starting from betulin (3) has been accomplished in 12 steps with a total yield of 10% in our study. Compound 1 and selected synthetic intermediates were further evaluated as anti-HIV-1 agents, inhibitors of glycogen phosphorylase (GP), and cytotoxic agents. Compound 1 exhibited moderate HIV-1 inhibition. Most importantly, compound 5, with an opened A-ring, showed significant GP inhibitory activity with an IC50 of 0.21 μM, suggesting a potential for development as an anti-diabetic agent. On the other hand, compound 12, with a closed A-ring, showed potent cytotoxicity against A549 and MCF-7 human tumor cell lines, with IC50 values of 0.89 and 0.33 μM, respectively. These results suggest that the A-ring of PTs is an important pharmacophore that could be modified to involve different biological activities.
Unambiguous atomic Bell measurement assisted by multiphoton states
Creators: name: Torres, Juan Mauricio
name: Bernád, József Zsolt
name: Alber, Gernot
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose and theoretically investigate an unambiguous Bell measurement of atomic qubits assisted by multiphoton states. The atoms interact resonantly with the electromagnetic field inside two spatially separated optical cavities in a Ramsey-type interaction sequence. The qubit states are postselected by measuring the photonic states inside the resonators. We show that if one is able to project the photonic field onto two coherent states on opposite sites of phase space, an unambiguous Bell measurement can be implemented. Thus our proposal may provide a core element for future components of quantum information technology such as a quantum repeater based on coherent multiphoton states, atomic qubits and matter-field interaction.
description: 11 pages, 6 figures
New betulinic acid derivatives as potent proteasome inhibitors
Creators: name: Kim, Sang Yong
name: Hung, Hsin Yi
name: Chen, Chin Ho
name: Huang, Li
name: Lee, Kuo Hsiung
name: Qian, Keduo
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: In this study, 22 new betulinic acid (BA) derivatives were synthesized and tested for their inhibition of the chymotrypsin-like activity of 20S proteasome. From the SAR study, we concluded that the C-3 and C-30 positions are the pharmacophores for increasing the proteasome inhibition effects, and larger lipophilic or aromatic side chains are favored at these positions. Among the BA derivatives tested, compounds 13, 20, and 21 showed the best proteasome inhibition activity with IC50 values of 1.42, 1.56, and 1.80 µM, respectively, which are three- to four-fold more potent than the proteasome inhibition controls LLM-F and lactacystin.
ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide
Creators: name: Wang, Xihong
name: Lee, Kuo Hsiung
name: Soares, Joana
name: Jarstfer, Michael B.
name: Keppler, Brian R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The tanshinone natural products possess a variety of pharmacological properties including anti-bacterial, anti-inflammatory, anti-oxidant, and anti-neoplastic activity. The molecular basis of these effects, however, remains largely unknown. In the present study, we explored the direct effect of tanshinones on the enzyme telomerase. Telomerase is up-regulated in the majority of cancer cells and is essential for their survival, making it a potential anti-cancer drug target. We found that the ortho-quinone tanshinone II-A inhibits telomerase in a time- and DTT-dependent fashion, and the hydrogen peroxide scavenger catalase protected telomerase from inactivation. These findings demonstrate that ortho-quinone containing tanshinones can inhibit telomerase owing to their ability to generate reactive oxygen species. The results also provide evidence that telomerase is directly and negatively regulated by reactive oxygen species.
(102871) Emma May Edwards
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
On the Unique Reconstruction of Induced Spherical Magnetizations
Creators: name: Gerhards, Christian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: Recovering spherical magnetizations $m$ from magnetic field data in the exterior is a highly non-unique problem. A spherical Hardy-Hodge decomposition supplies information on what contributions of the magnetization $m$ are recoverable but it does not supply geophysically suitable constraints on $m$ that would guarantee uniqueness for the entire magnetization. In this paper, we focus on the case of induced spherical magnetizations and show that uniqueness is guaranteed if one assumes that the magnetization is compactly supported on the sphere. The results are based on ideas presented in Baratchart et al. (2013) for the planar setting.
description: Minor correction in proof of Theorem 3.2
Metallicity beats sSFR: The connection between superluminous supernova host galaxy environments and the importance of metallicity for their production
Creators: name: Cleland, Cressida
name: McGee, Sean L.
name: Nicholl, Matt
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We analyse 33 Type I superluminous supernovae (SLSNe) taken from ZTF's Bright Transient Survey to investigate the local environments of their host galaxies. We use a spectroscopic sample of galaxies from the SDSS to determine the large-scale environmental density of the host galaxy. Noting that SLSNe are generally found in galaxies with low stellar masses, high star formation rates, and low metallicities, we find that SLSN hosts are also rarely found within high-density environments. Only $3\substack{+9 \\-1}$ per cent of SLSN hosts were found in regions with 2 or more bright galaxies within 2 Mpc. For comparison, we generate a sample of 662 SDSS galaxies matched to the photometric properties of the SLSN hosts. This sample is also rarely found within high-density environments, suggesting that galaxies with properties required for SLSN production favour more isolated environments. Furthermore, we select galaxies within the Illustris-TNG simulation to match SLSN host galaxy properties in colour and stellar mass. We find that the fraction of simulated galaxies in high-density environments quantitatively matches the observed SLSN hosts only if we restrict to simulated galaxies with metallicity $12+\log($O/H$) \leq 8.12$. In contrast, limiting to only the highest sSFR galaxies in the sample leads to an overabundance of SLSN hosts in high-density environments. Thus, our measurement of the environmental density of SLSN host galaxies appears to break the degeneracy between low-metallicity or high-sSFR as the driver for SLSN hosts and provides evidence that the most constraining factor on SLSN production is low-metallicity.
description: Accepted to MNRAS, 10 pages, 6 figures. Re-uploaded for updating references
(102870) Jessica Helen May Leslie
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Accretion Properties and Estimation of Spin of Galactic Black Hole Candidate Swift J1728.9-3613 with NuSTAR during its 2019 outburst
Creators: name: Heiland, Skye R.
name: Chatterjee, Arka
name: Safi-Harb, Samar
name: Jana, Arghajit
name: Heyl, Jeremy
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Black hole X-ray binaries (BHXRBs) play a crucial role in understanding the accretion of matter onto a black hole. Here, we focus on exploring the transient BHXRB \source~discovered by Swift/BAT and MAXI/GSC during its January 2019 outburst. We present measurements on its accretion properties, long time-scale variability, and spin. To probe these properties we make use of several NICER observations and an unexplored data set from NuSTAR, as well as long term light curves from MAXI/GSC. In our timing analysis we provide estimates of the cross-correlation functions between light curves in various energy bands. In our spectral analysis we employ numerous phenomenological models to constrain the parameters of the system, including flavours of the relativistic reflection model Relxill to model the Fe K$α$ line and the $>15$ keV reflection hump. Our analysis reveals that: (i) Over the course of the outburst the total energy released was $\sim 5.2 \times 10^{44}$~ergs, corresponding to roughly 90\% the mass of Mars being devoured. (ii) We find a continuum lag of $8.4 \pm 1.9$ days between light curves in the $2-4$ keV and $10-20$ keV bands which could be related to the viscous inflow time-scale of matter in the standard disc. (iii) Spectral analysis reveals a spin parameter of $\sim 0.6 - 0.7$ with an inclination angle of $\sim 45^{\circ}-70^{\circ}$, and an accretion rate during the NuSTAR observation of $\sim 17\% ~L_{\rm Edd}$.
description: 13 pages 6 figures, Accepted for publication in MNRAS, Comments are welcome
Synthesis and biological evaluation of new salvinorin A analogues incorporating natural amino acids
Creators: name: Roth, Bryan L.
name: Lewellyn, Kevin
name: Fichna, Jakub
name: Zjawiony, Jordan K.
name: Yan, Feng
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The synthesis and in vitro evaluation of a new series of salvinorin A analogues substituted at the C(2) position with natural amino acids is reported. Compound 12, containing Val, displayed high affinity and full agonist activity at the kappa-opioid receptor. Analogues with bulky and/or aromatic residues were inactive, showing the importance of size and electronegativity of C(2)-substituents for binding affinity of salvinorin A derivatives.
Synthesis and proteasome inhibition of lithocholic acid derivatives
Creators: name: Lee, Kuo Hsiung
name: Dang, Zhao
name: Ho, Phong
name: Soroka, Dominique
name: Lin, Andrew
name: Chen, Chin Ho
name: Huang, Li
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: A new class of proteasome inhibitors was synthesized using lithocholic acid as a scaffold. Modification at the C-3 position of lithocholic acid with a series of acid acyl groups yielded compounds with a range of potency on proteasome inhibition. Among them, the phenylene diacetic acid hemiester derivative (13) displayed the most potent proteasome inhibition with IC50 = 1.9 μM. Enzyme kinetic analysis indicates that these lithocholic acid derivatives are non-competitive inhibitors of the proteasome.
(102708) Katherine Symonds
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.