cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Cancer Stem- Like Cells in Melanoma Progression, Resistance and Recurrence: Significance for Melanoma Treatment
Creators: name: M, Hassan
name: A, El Khattouti
name: Y, Haikel
name: Megahed M
Publisher: name: figshare
Year: 2018
Subjects: subject: 110708 Transplantation Immunology
subject: FOS: Clinical medicine

description: Human malignant melanoma is a highly aggressive tumor which demonstrates heterogeneity and a propensity to drug resistance. Despite improved treatment options, patients with advanced malignant melanoma continue have a poor prognosis as measured by progression-free and overall survival. The cancer stem-like cell (CSC) hypothesis suggests that neoplastic clones are maintained by a small fraction of cells with stem cell properties. As has been demonstrated with other tumor types, melanoma progression, resistance to chemo- and radiotherapy, and recurrence can be attributed to a small fraction of cells termed melanoma stem-like cells (MSCs). These MSCs are characterized by a distinct protein patterns and aberrant signaling pathways, which are either in a causal or consequential relationship to tumor progression, drug resistance and recurrence. This review focuses on the mechanistic role of MSCs leading to tumor progression and metastasis, resistance and recurrence. Understanding the molecular mechanisms underlying MSCs migration, invasion, resistance to standard treatments, and recurrence may help to improve current therapeutic modalities and/or pave the way for the development of new therapeutical management strategy for tumor treatment.
Additional file 3 of Integrated analysis of miRNA and mRNA expression profiles in testes of Duroc and Meishan boars
Creators: name: Ding, Haisheng
name: Liu, Min
name: Zhou, Changfan
name: You, Xiangbin
name: Su, Tao
name: Yang, Youbing
name: Xu, Dequan
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3: Figure S1. Expression analyses of 4 DE miRNAs and 4 DEGs using qRT-PCR and RNA-Seq. Analyses of relative expression levels of miRNAs and genes in Duroc (black bars) and Meishan (gray bars) boars in the left; RPKM of miRNAs and genes in Duroc (blue bars) and Meishan (purple bars) boars a in the right. The X-axis indicates age of samples. The left Y-axis and right Y-axis show the relative expression level and RPKM of miRNAs and genes, respectively. a ssc-mir-181b, b ssc-mir-423-5p, c ssc-mir-196b-5p, d ssc-mir-4334-3p, e CYLD, f CDYL, g PLCβ1, h SOX30. **P < 0.01, *P < 0.05. DE miRNAs, differentially expressed miRNAs; DEGs, differentially expressed genes; qRT-PCR, quantitative real-time PCR; RNA-Seq, RNA sequencing; RPKM, Reads Per Kilobase per Million mapped reads; CYLD, Cylindromatosis; CDYL, chromodomain Y like; PLCβ1, phospholipase C beta 1; SOX30, SRY-box containing gene 30.
Malen und Musik - Konzentrationsföderung in der Psychomotoriktherapie Theoretische Hintergründe und praktische Übungen für die Psychomotoriktherapie
Creators: name: Klotz, Rahel
name: Long, Gingi
Publisher: name: Zenodo
Year: 2017
Subjects: Psychomotorik
Psychomotoriktherapie
Musik- und Bewegungserziehung
Malen
Bachelorarbeit

description: Die vorliegende Arbeit befasst sich mit dem Thema Musik und Malen als Konzentrationsförderung. Sie beschäftigt sich mit der Frage, inwiefern Musik und Malen die Konzentration positiv beeinflussen kann. Dafür wurde in einer Literaturrecherche nach Studien gesucht, die Hinweise dazu geben. Ergänzt wurde das theoretische Wissen durch praktische Erfahrungen von zwei Interviewpartnern aus den Bereichen Musik- und Maltherapie. Weiter wurden in dieser Arbeit Übungen für die Psychomotoriktherapie entwickelt, aufbauend auf praktischer Erfahrung, die theoretisch hinterlegt werden konnte. Wir ziehen den Schluss, dass sich der Einsat von Musik und Malen mit konzentrationsfördernden Komponenten für die Psychomotoriktherapie eignet. Dazu müssen gewisse Elemente beachtet werden; Elemente, auf die in der Diskussion eingegangen wird.
Effect of Snake Venom Disintegrin like domain on the Homing of Mesenchymal Stem Cells
Creators: name: EL-Wahab DA
name: WS, Zaki
name: EK, Habib
name: AR, Basheer
name: TM, Farid
name: Nasser, Hanaa EL.T.
name: EL-Asmar MF
Publisher: name: figshare
Year: 2018
Subjects: subject: 110708 Transplantation Immunology
subject: FOS: Clinical medicine

description: Mesenchymal stem cells have many advantages as grafts for cell transplantation. The homing of MSCs after systemic infusion is still poorly understood. This report explored the effect of the combination of BM-MSCs with Disintegrin like fraction obtained from Cerastes cerastes crude venom on the fibrotic liver of CCl4 treated mice. It was observed that Disintegrin like fraction could increase homing of BM-MSCs labeled with the PKH26 into the liver tissue of CCl4 treated mice. A significant decrease in AST and ALT serum levels after administration of Disintegrin like fraction and/or BM-MSCs in CCl4 treated mice were detected. VEGF was expressed in mice injected with CCl4 alone, followed by Disintegrin like fraction or both Disintegrin like fraction and BM-MSCs. β- catenin was expressed in mice injected with CCl4 alone, followed by BM-MSCs or both BM-MSCs and Disintegrin like fraction. Caspase-3 gene was expressed in CCl4 treated mice injected with BM-MSCs or both BM-MSCs and Disintegrin like fraction. TNF-α and HO-1 were expressed in all groups. Administration of Disintegrin like fraction and / or BM-MSCs improved the histo-pathological picture and showed signs of regeneration in CCl4 induced liver fibrosis. In conclusion, Disintegrin like fraction could increase homing of BM-MSCs into the liver tissue of CCl4 treated mice. Further studies need to be done to explore the mechanism of homing caused by Disintegrin.
The Great Observatories All-Sky LIRG Survey: Herschel Image Atlas and Aperture Photometry
Creators: name: Chu, Jason K.
name: Sanders, D. B.
name: Larson, K. L.
name: Mazzarella, J. M.
name: Howell, J. H.
name: Díaz-Santos, T.
name: Xu, K. C.
name: Paladini, R.
name: Schulz, B.
name: Shupe, D.
name: Appleton, P.
name: Armus, L.
name: Billot, N.
name: Chan, B. H. P.
name: Evans, A. S.
name: Fadda, D.
name: Frayer, D. T.
name: Haan, S.
name: Ishida, C. M.
name: Iwasawa, K.
name: Kim, D. -C.
name: Lord, S.
name: Murphy, E.
name: Petric, A.
name: Privon, G. C.
name: Surace, J. A.
name: Treister, E.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Far-infrared (FIR) images and photometry are presented for 201 Luminous and Ultraluminous Infrared Galaxies [LIRGs: log$(L_{\rm IR}/L_\odot) = 11.00 - 11.99$, ULIRGs: log$(L_{\rm IR}/L_\odot) = 12.00 - 12.99$], in the Great Observatories All-Sky LIRG Survey (GOALS) based on observations with the $Herschel$ $Space$ $Observatory$ Photodetector Array Camera and Spectrometer (PACS) and the Spectral and Photometric Imaging Receiver (SPIRE) instruments. The image atlas displays each GOALS target in the three PACS bands (70, 100, and 160 $μ$m) and the three SPIRE bands (250, 350, and 500 $μ$m), optimized to reveal structures at both high and low surface brightness levels, with images scaled to simplify comparison of structures in the same physical areas of $\sim$$100\times100$ kpc$^2$. Flux densities of companion galaxies in merging systems are provided where possible, depending on their angular separation and the spatial resolution in each passband, along with integrated system fluxes (sum of components). This dataset constitutes the imaging and photometric component of the GOALS Herschel OT1 observing program, and is complementary to atlases presented for the Hubble Space Telescope (Evans et al. 2017, in prep.), Spitzer Space Telescope (Mazzarella et al. 2017, in prep.), and Chandra X-ray Observatory (Iwasawa et al. 2011, 2017, in prep.). Collectively these data will enable a wide range of detailed studies of AGN and starburst activity within the most luminous infrared galaxies in the local Universe.
description: Accepted for publication in ApJS, 270 pages, 216 figures, 4 tables
A transposable element insertion is associated with an alternative life history strategy.
Creators: name: Woronik, Alyssa
name: Tunström, Kalle
name: Perry, Michael W
name: Neethiraj, Ramprasad
name: Stefanescu, Constanti
name: Celorio-Mancera, Maria De La Paz
name: Brattström, Oskar
name: Hill, Jason
name: Lehmann, Philipp
name: Käkelä, Reijo
name: Wheat, Christopher W
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019

description: Tradeoffs affect resource allocation during development and result in fitness consequences that drive the evolution of life history strategies. Yet despite their importance, we know little about the mechanisms underlying life history tradeoffs. Many species of Colias butterflies exhibit an alternative life history strategy (ALHS) where females divert resources from wing pigment synthesis to reproductive and somatic development. Due to this reallocation, a wing color polymorphism is associated with the ALHS: either yellow/orange or white. Here we map the locus associated with this ALHS in Colias crocea to a transposable element insertion located downstream of the Colias homolog of BarH-1, a homeobox transcription factor. Using CRISPR/Cas9 gene editing, antibody staining, and electron microscopy we find white-specific expression of BarH-1 suppresses the formation of pigment granules in wing scales and gives rise to white wing color. Lipid and transcriptome analyses reveal physiological differences associated with the ALHS. Together, these findings characterize a mechanism for a female-limited ALHS.
Merina und Dylan: Abenteuer unter Wasser Ein interaktives Bilderbuch für die psychomotorische Prävention im Wasser
Creators: name: Räss, Angela
Publisher: name: Zenodo
Year: 2017
Subjects: Psychomotorik
Psychomotoriktherapie
Wasserkunst
Bachelorarbeit

description: In dieser Entwicklungsarbeit steht der Prozess der Gestaltung eines interaktiven Bilderbuchs zur psychomotorischen Prävention im Wasser im Fokus. Dabei soll zu Beginn geklärt werden, was Psychomotoriktherapie im Wasser ist. Des Weiteren wird die psychomotorische Prävention bezüglich ihres Inhalts betrachtet. In einem weiteren Schritt soll aufgezeigt werden, wie die Stundengestaltung und Übungsauswahl bei der psychomotorischen Arbeit im Wasser aussehen kann. Es soll aufgezeigt werden, was es zu beachten gilt bezüglich der Gestaltung eines Bilderbuches und wie ein Bilderbuch mit interaktivem Charakter entsteht. Im Fokus dieser Arbeit steht der eigentliche Prozess der Entstehung dieses interaktiven Bilderbuchs.
Effect of Bone Marrow-derived Mesenchymal Stem Cells and Umbilical Cord Blood-CD34+ cells on Experimental Rat liver Fibrosis
Creators: name: RH, Ahmed
name: Roshdy NK
name: MI, Aref
name: NM, Hassan
name: HE, Saleh
name: NR, Mohammed
Publisher: name: figshare
Year: 2018
Subjects: subject: 110708 Transplantation Immunology
subject: FOS: Clinical medicine

description: Background and Objective: Liver disease is one of the major causes of death in many countries. Hence, the development of effective therapies for liver fibrosis is a major aim of medical research. So this study was designed to investigate the therapeutical role of mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs) transplantation in the experimental rat liver fibrosis. Design and Method: Bone marrow-derived MSCs were isolated from femoral and tibial bones of male albino rats, then were grown and propagated in culture for 2 weeks and were characterized morphologically and by detection of CD29 by real time-PCR. Human umbilical cord blood cells were obtained after full-term caesarean delivery from healthy donors after written informed consent. Low-density mononuclear cells were separated over Ficoll- Paque (Gibco-Invitrogen, Grand Island, NY), and then CD34+ HSC was isolated using a magnetic cell sorter (MiniMACS; Miltenyi Biotec, Bergisch Gladbach, Germany). The cells were then infused intraperitoneally in rats that received CCl4 injection to induce liver fibrosis. Rats were divided into 4 groups: control, CCl4, CCl4 plus MSC, and CCl4 plus CD34+. Liver tissue was examined histopathologically for all groups. The expression of collagen I and metalloproteinase-2 genes as a marker of liver fibrosis was measured by real time RT- PCR. Results: The results of the present study showed that both MSCs and CD34+ have a significant antifibrotic effect as evidenced by the significant decrease in liver collagen gene expression as well as the decrease in MMP-2 (p < 0.05) compared to the CCl4 group.
Soziale Interaktion in Bewegungslandschaften mit Kindern von Asylsuchenden in der Schweiz Ein Projekt mit Bewegungslandschaften in Aufnahmeklassen
Creators: name: Warmers, Clara Sophia
Publisher: name: Zenodo
Year: 2017
Subjects: Psychomotorik
Psychomotoriktherapie
Interaktion
Kind
Asylbewerber
Bachelorarbeit

description: In dieser Arbeit wird ein Projekt von Bewegungslandschaften mit Kindern von Asylsuchenden in Auf-nahmeklassen vorgestellt. In der Literaturverarbeitung werden Bewegungslandschaften, die soziale Interaktion und die Thematik der Kinder von Asylsuchenden in der Schweiz dargestellt. Untersucht wurden zwei Fragestellungen: Inwiefern speziell Kinder von Asylsuchenden von Bewegungslandschaften profitieren können und wie sich die verschiedenen Bereiche der sozialen Interaktion der Kinder innerhalb der Bewegungslandschaft verändern. Die soziale Interaktion wurde anhand von Beobachtungsbögen, welche Bereiche der sozialen Interak-tion beinhalten, ausgewertet. In der Analyse wurde der zeitliche Ablauf der Bereiche angeschaut. Es zeigte sich, dass Bewegungslandschaften vielfältige Chancen für die Kinder bieten. Es liessen sich unterschiedliche Verlaufsmuster der Bereiche der sozialen Interaktion erkennen.
The best fit for the observed galaxy Counts-in-Cell distribution function
Creators: name: Hurtado-Gil, Ll.
name: Martínez, V. J.
name: Arnalte-Mur, P.
name: Pons-Bordería, M. J.
name: Pareja-Flores, C.
name: Paredes, S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The Sloan Digital Sky Survey (SDSS) is the first dense redshift survey encompassing a volume large enough to find the best analytic probability density function that fits the galaxy Counts-in-Cells distribution $f_V(N)$, the frequency distribution of galaxy counts in a volume $V$. Different analytic functions have been previously proposed that can account for some of the observed features of the observed frequency counts, but fail to provide an overall good fit to this important statistical descriptor of the galaxy large-scale distribution. Our goal is to find the probability density function that better fits the observed Counts-in-Cells distribution $f_V(N)$. We have made a systematic study of this function applied to several samples drawn from the SDSS. We show the effective ways to deal with incompleteness of the sample (masked data) in the calculation of $f_V(N)$. We use LasDamas simulations to estimate the errors in the calculation. We test four different distribution functions to find the best fit: the Gravitational Quasi-Equilibrium distribution, the Negative Binomial Distribution, the Log Normal distribution and the Log Normal Distribution including a bias parameter. In the two latter cases, we apply a shot-noise correction to the distributions assuming the local Poisson model. We show that the best fit for the Counts-in-Cells distribution function is provided by the Negative Binomial distribution. In addition, at large scales the Log Normal distribution modified with the inclusion of the bias term also performs a satisfactory fit of the empirical values of $f_V(N)$. Our results demonstrate that the inclusion of a bias term in the Log Normal distribution is necessary to fit the observed galaxy Count-in-Cells distribution function.
description: 12 pages, 16 figures. Accepted for publication in Astronomy & Astrophysics
Potentilla procumbens subsp. nesogenes Briq.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rosaceae
Potentilla
Potentilla procumbens
Potentilla procumbens subsp. nesogenes briq.

description: Potentilla procumbens subsp. nesogenes Briq., Prodr. Fl. Corse 2(1): 193. 1913 (fig. 2).
Lectotypus (hic designatus): FRANCE. Corse: Monte Renoso, 1800 m, 24.VII.1900, E. Burnat, Briquet & Cavillier 381 (G-BU [G00830139]!).
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 69, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
Pertinence between risk of preeclampsia and the renin-angiotensin-aldosterone system (RAAS) gene polymorphisms: an updated meta-analysis based on 73 studies
Creators: name: Wang, Xin
name: Kong, Yujie
name: Chen, Xi
name: Weng, Zhanping
name: Li, Baolai
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: The aetiological mechanism of preeclampsia (PE) is unclear exactly, so we attempted to investigate the association between susceptibility to preeclampsia and renin-angiotensin-aldosterone system (RAAS) gene polymorphisms to explore the aetiology in terms of genetics. A systematic search was performed in electronic databases to identify relevant studies. Eventually 73 studies were enrolled, odds ratios were generated by 5 genetic models. In overall analysis, significant associations were detected for AGT M235T, AT1R A1166C and CYP11B2 C344T whereas negative correlation was shown for AGT T174M. As stratified by race and geography, AGT 235T allele and AT1R 1166C allele increased preeclampsia risk and AGT T174M was justified uncorrelated with preeclampsia. Our meta-analysis illustrated that AGT 235T allele and AT1R 1166C allele increased and CYP11B2 344T allele decreased preeclampsia risk while AGT T174M polymorphism did not change preeclampsia risk. Hence, pregnant women carrying high-risk genotypes need strengthened management to prevent and early identification of preeclampsia.
Quantum Black Hole Entropy, Localization and the Stringy Exclusion Principle
Creators: name: Gomes, Joao
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Supersymmetric localization has lead to remarkable progress in computing quantum corrections to BPS black hole entropy. The program has been successful especially for computing perturbative corrections to the Bekenstein-Hawking area formula. In this work, we consider non-perturbative corrections related to polar states in the Rademacher expansion, which describes the entropy in the microcanonical ensemble. We propose that these non-perturbative effects can be identified with a new family of saddles in the localization of the quantum entropy path integral. We argue that these saddles, which are euclidean $AdS_2\times S^1\times S^2$ geometries, arise after turning on singular fluxes in M-theory on a Calabi-Yau. They cease to exist after a certain amount of flux, resulting in a finite number of geometries; the bound on that number is in precise agreement with the stringy exclusion principle. Localization of supergravity on these backgrounds gives rise to a finite tail of Bessel functions in agreement with the Rademacher expansion. As a check of our proposal, we test our results against well-known microscopic formulas for one-eighth and one-quarter BPS black holes in $\mathcal{N}=8$ and $\mathcal{N}=4$ string theory respectively, finding agreement. Our method breaks down precisely when mock-modular effects are expected in the entropy of one-quarter BPS dyons and we comment upon this. Furthermore, we mention possible applications of these results, including an exact formula for the entropy of four dimensional $\mathcal{N}=2$ black holes.
description: 66 pages
Auswirkungen persistierender primitiver Reflexe Die Sicht des Instituts für Neuro-Physiologische Psychologie im Vergleich mit anderen Disziplinen
Creators: name: Hinder, Anja
Publisher: name: Zenodo
Year: 2017
Subjects: Psychomotorik
Psychomotoriktherapie
Reflex
Bachelorarbeit

description: Diese Bachelor-Arbeit beschäftigt sich mit Auswirkungen persistierender primitiver Reflexe und der Neurophysiologischen Entwicklungsförderung NDT/INPP. Mittels einer ausführlichen Literaturrecherche werden verschiedene Sichtweisen zum Thema verglichen, die Sicht des Instituts für Neuro-Physiologische Psychologie steht dabei im Mittelpunkt. Die Literaturanalyse zeigt, dass dieses Institut von Restreaktionen primitiver Reflexe ausgeht, welche viele Auswirkungen haben können, während Studien anderer Disziplinen sich vorwiegend auf stark persistierende primitive Reflexe mit pathologischen Auswirkungen beschränken. Die wenigen Wirksamkeitsstudien bestätigen die Wirksamkeit der Neurophysiologischen Entwicklungsförderung NDT/INPP für den Rückgang von Restreaktionen primitiver Reflexe. Die Neurophysiologische Entwicklungsförderung NDT/INPP ist in gewissen Fällen eine sinnvolle Ergänzung zur PMT.
Additional file 1 of A comparative study of international and Chinese public health emergency management from the perspective of knowledge domains mapping
Creators: name: Li, Juan
name: Zhu, Yuhang
name: Feng, Jianing
name: Meng, Weijing
name: Begma, Kseniia
name: Zhu, Gaopei
name: Wang, Xiaoxuan
name: Wu, Di
name: Shi, Fuyan
name: Wang, Suzhen
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 1: Table S1. Top 10 authors in the published volume and centrality of international database. Table S2. Top 10 authors in the published volume and centrality of Chinese database. Table S3. Top 10 institutions in the published volume and centrality of international database. Table S4. Top 10 institutions in the published volume and centrality of Chinese database. Table S5. Top 10 keywords ranked by citation counts and centrality of international database. Table S6. Top 10 keywords ranked by citation counts and centrality of Chinese database. Figure S1. Co-author network of Chinese database. Figure S2. Co-institution network of Chinese database. Figure S3. Keyword co-occurrence network of Chinese database. Figure S4. Keywords with the strongest citation bursts of Chinese database.
Human Peripheral Blood Derived Hematopoietic Stem Cell: History, the Isolation Methods and Investigation of Different Parameters Effects on Their Differentiation to the Body Cells
Creators: name: Mohammadi H
name: Mohammadnejad J
name: Yavari K
Publisher: name: figshare
Year: 2018
Subjects: subject: 110708 Transplantation Immunology
subject: FOS: Clinical medicine

description: Blood and the system that forms it, known as the hematopoietic system, consist of many cell types with specialized functions. Red blood cells (erythrocytes) carry oxygen to the tissues. Platelets (derived from megakaryocytes) help prevent bleeding. Granulocytes (neutrophils, basophils and eosinophils) and macrophages (collectively known as myeloid cells) fight infections from bacteria, fungi, and other parasites such as nematodes (ubiquitous small worms). Some of these cells are also involved in tissue and bone remodeling and removal of dead cells. B-lymphocytes produce antibodies, while T-lymphocytes can directly kill or isolate by inflammation cells recognized as foreign to the body, including many virus-infected cells and cancer cells. Many blood cells are short-lived and need to be replenished continuously; the average human requires approximately one hundred billion new hematopoietic cells each day. The continued production of these cells depends directly on the presence of Hematopoietic Stem Cells (HSCs), the ultimate, and only, source of all these. Peripheral blood stem cells (PBSC) are rapidly becoming the primary rescue modality for autologous transplantation and are now actively being investigated in the allogeneic transplant setting. Many investigators and clinical researchers believe that PBSC are likely to replace bone marrow stem cells entirely, for use in clinical transplantation in the not too distant. Hematopoietic stem cells (HSCs) are the blood cells that give rise to all the other blood cells. They give rise to the myeloid (monocytes and macrophages, neutrophils, basophils, eosinophils, erythrocytes, megakaryocytes/platelets, dendritic cells), and lymphoid lineages (T-cells, B-cells, NK-cells). The definition of hematopoietic stem cells has changed in the last two decades. The hematopoietic tissue contains cells with long-term and short-term regeneration capacities and committed multipotent, oligopotent, and unipotent progenitors.
Bayesian Varying-Effects Vector Autoregressive Models for Inference of Brain Connectivity Networks and Covariate Effects in Pediatric Traumatic Brain Injury
Creators: name: Ren, Yangfan
name: Osborne, Nathan
name: Peterson, Christine B.
name: DeMaster, Dana M.
name: Ewing-Cobbs, Linda
name: Vannucci, Marina
Publisher: name: arXiv
Year: 2024
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: In this paper, we develop an analytical approach for estimating brain connectivity networks that accounts for subject heterogeneity. More specifically, we consider a novel extension of a multi-subject Bayesian vector autoregressive model that estimates group-specific directed brain connectivity networks and accounts for the effects of covariates on the network edges. We adopt a flexible approach, allowing for (possibly) non-linear effects of the covariates on edge strength via a novel Bayesian nonparametric prior that employs a weighted mixture of Gaussian processes. For posterior inference, we achieve computational scalability by implementing a variational Bayes scheme. Our approach enables simultaneous estimation of group-specific networks and selection of relevant covariate effects. We show improved performance over competing two-stage approaches on simulated data. We apply our method on resting-state fMRI data from children with a history of traumatic brain injury and healthy controls to estimate the effects of age and sex on the group-level connectivities. Our results highlight differences in the distribution of parent nodes. They also suggest alteration in the relation of age, with peak edge strength in children with traumatic brain injury (TBI), and differences in effective connectivity strength between males and females.
Principal fiber bundles in non-commutative geometry
Creators: name: Kassel, Christian
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 16T05, 17B37, 55R10, 81R60, 81R50

description: These are the expanded notes of a course given at the Summer school "Geometric, topological and algebraic methods for quantum field theory" held at Villa de Leyva, Colombia in July 2015. We first give an introduction to non-commutative geometry and to the language of Hopf algebras. We next build up a theory of non-commutative principal fiber bundles and consider various aspects of such objects. Finally, we illustrate the theory using the quantum enveloping algebra $U_q\mathfrak{sl}(2)$ and related Hopf algebras.
description: 50 pages, including table of contents and index
Additional file 2 of Characteristics of the urinary microbiome in kidney stone patients with hypertension
Creators: name: Liu, Fengping
name: Zhang, Nan
name: Jiang, Peng
name: Zhai, Qixiao
name: Li, Chen
name: Yu, Deshui
name: Wu, Yan
name: Zhang, Yuwei
name: Lv, Longxian
name: Xu, Xinyu
name: Feng, Ninghan
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Physiology
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Table S1. Comparison of bacterial genus abundance in groups. Wilcoxon rank-sum test was used to compare the difference of abundance between two groups, and a, b, c means that there was significant difference between groups of HC and KSD-NTN, between groups HC and KSD-pHTN, between groups of HC and KSD-HTN (p < 0.05). Abbreviations: HC, healthy controls; HTN, hypertension; KSD, kidney stone disease; NTN, normotension; pHTN, pre-hypertension.
Beliebtheit im Kindergarten Eine Untersuchung über den Zusammenhang von Leistungen in der Grobmotorik und Beliebtheit bei Kindern im Alter von 4 bis 6 Jahren
Creators: name: von Wartburg, Evelyn
Publisher: name: Zenodo
Year: 2017
Subjects: Psychomotorik
Psychomotoriktherapie
Vorschulerziehung
Kind
Grobmotorik
Bachelorarbeit

description: In dieser Bachelorarbeit wird untersucht, ob bei Kindern im Alter von 4 bis 6 Jahren ein Zu-sammenhang zwischen Leistungen in der Grobmotorik und der Beliebtheit besteht. In zwei Kindergärten mit insgesamt 33 Kindern wurde mittels soziometrischer Befragung die Beliebt-heit der Kinder gemessen und mit dem M-ABC-2 die grobmotorischen Leistungen der Kinder erhoben. Da aus der Forschung mit Schulkindern bekannt ist, dass es auch Zusammenhänge von kognitiven Leistungen und der Beliebtheit gibt, wurden mit Hilfe eines Lehrer-Fragebogens zusätzlich Auffälligkeiten zu den Bereichen Sprache und ADHS erhoben und ebenfalls mit der Beliebtheit in Verbindung gebracht.
 Es wurde kein signifikanter Zusammenhang zwischen der Beliebtheit und den grobmotori-schen Leistungen gefunden. Bei den Mädchen hat sich jedoch ein signifikanter Zusammen-hang zwischen ADHS und Beliebtheit gezeigt.
Additional file 6 of Integrated analysis of miRNA and mRNA expression profiles in testes of Duroc and Meishan boars
Creators: name: Ding, Haisheng
name: Liu, Min
name: Zhou, Changfan
name: You, Xiangbin
name: Su, Tao
name: Yang, Youbing
name: Xu, Dequan
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 6: Figure S3. Western blotting analysis was used to detect PLCβ1 protein expression levels at 72 h after ST cells were transfected with ssc-mir-423-5p mimic /mimic NC or ssc-mir-423-5p inhibitor /inhibitor NC.
Multi-Haul Quasi Network Flow Model for Vertical Alignment Optimization
Creators: name: Beiranvand, Vahid
name: Hare, Warren
name: Lucet, Yves
name: Hossain, Shahadat
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: G.1.6; I.6.4; J.6
subject: 90C90 (Primary), 90C11 (Secondary)

description: The vertical alignment optimization problem for road design aims to generate a vertical alignment of a new road with a minimum cost, while satisfying safety and design constraints. We present a new model called multi-haul quasi network flow (MH-QNF) for vertical alignment optimization that improves the accuracy and reliability of previous mixed integer linear programming models. We evaluate the performance of the new model compared to two state-of-the-art models in the field: the complete transportation graph (CTG) and the quasi network flow (QNF) models. The numerical results show that, within a 1% relative error, the proposed model is robust and solves more than 93% of test problems compared to 82% for the CTG and none for the QNF. Moreover, the MH-QNF model solves the problems approximately 8 times faster than the CTG model.
description: 23 pages, 4 figures The Version of Record of this manuscript has been published and is available in Engineering Optimization (GENO); Estimated publication date: Jan 12, 2017 (online); http://dx.doi.org/10.1080/0305215X.2016.1271880
Anomalous phonon Grüneisen parameters in semiconductor Ta$_2$NiS$_5$
Creators: name: Ye, Mai
name: Lacmann, Tom
name: Frachet, Mehdi
name: Vinograd, Igor
name: Garbarino, Gaston
name: Maraytta, Nour
name: Merz, Michael
name: Heid, Rolf
name: Haghighirad, Amir-Abbas
name: Tacon, Matthieu Le
Publisher: name: arXiv
Year: 2024
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Strain tuning is a powerful experimental method in probing correlated electron systems. Here we study the strain response of the lattice dynamics and electronic structure in semiconductor Ta$_2$NiS$_5$ by polarization-resolved Raman spectroscopy. We observe an increase of the size of the direct semiconducting band gap. Although the majority of the optical phonons show only marginal dependence to applied strain, the frequency of the two B$_{2g}$ phonon modes, which have quadrupolar symmetry and already anomalously soften on cooling under zero strain, increases significantly with tensile strain along the $a$ axis. The corresponding Grüneisen parameters are unusually large in magnitude and negative in sign. These effects are well captured by first-principles density functional theory calculations and indicate close proximity of Ta$_2$NiS$_5$ to a structural instability, similar to that encountered in excitonic insulator candidate Ta$_2$NiSe$_5$.
GC content shapes mRNA storage and decay in human cells.
Creators: name: Courel, Maïté
name: Clément, Yves
name: Bossevain, Clémentine
name: Foretek, Dominika
name: Vidal Cruchez, Olivia
name: Yi, Zhou
name: Bénard, Marianne
name: Benassy, Marie-Noëlle
name: Kress, Michel
name: Vindry, Caroline
name: Ernoult-Lange, Michèle
name: Antoniewski, Christophe
name: Morillon, Antonin
name: Brest, Patrick
name: Hubstenberger, Arnaud
name: Roest Crollius, Hugues
name: Standart, Nancy
name: Weil, Dominique
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Human
Post-transcriptional regulation
Codon usage
GC content
chromosomes
Gene Expression
Mrna Decay
P-bodies
Mrna Storage

description: mRNA translation and decay appear often intimately linked although the rules of this interplay are poorly understood. In this study, we combined our recent P-body transcriptome with transcriptomes obtained following silencing of broadly acting mRNA decay and repression factors, and with available CLIP and related data. This revealed the central role of GC content in mRNA fate, in terms of P-body localization, mRNA translation and mRNA stability: P-bodies contain mostly AU-rich mRNAs, which have a particular codon usage associated with a low protein yield; AU-rich and GC-rich transcripts tend to follow distinct decay pathways; and the targets of sequence-specific RBPs and miRNAs are also biased in terms of GC content. Altogether, these results suggest an integrated view of post-transcriptional control in human cells where most translation regulation is dedicated to inefficiently translated AU-rich mRNAs, whereas control at the level of 5' decay applies to optimally translated GC-rich mRNAs.
Wie wird die Psychomotorik und deren Wirkung retrospektiv wahrgenommen? Ehemalige Therapiekinder blicken zurück.
Creators: name: Schlatter, Mirjam Sina
name: Schwab, Anouk
Publisher: name: Zenodo
Year: 2017
Subjects: Psychomotorik
Psychmotoriktherapie
Bachelorarbeit

description: Diese Forschungsarbeit geht der Frage nach, wie Kinder, welche seit mindestens einem Jahr eine Psychomotoriktherapie abgeschlossen haben, diese bewerten. Im Theorieteil wird zuerst die Psychomotorik und deren Arbeitsweise vorgestellt. Insbesondere wird die grosse Vielfalt des psychomotorischen Arbeitens anhand der Beschreibung ausgewählter
 Perspektiven und Ansätze aufgezeigt. Zur Herleitung der Forschungsfragen wird danach auf den Fachdiskurs der Evaluations- und Wirksamkeitsforschung in der Psychomotorik eingegangen. Als Erhebungsinstrument zur Beantwortung der Forschungsfragen wurde ein Kinderfragebogen mit offenen und geschlossenen Fragen entworfen. Die drei Aspekte: „Befinden“, „Kompetenzerweiterung“ und „Transfer“ stehen dabei im Fokus der Befragung. Die Ergebnisse werden deskriptiv ausgewertet und diskutiert. Zusammenfassend kann gesagt werden, dass alle fünfzehn Kinder der Stichprobe die Psychomotorik in guter Erinnerung haben und eine Kompetenzerweiterung wahrnehmen konnten.
Prospects of Light Sterile Neutrino Oscillation and CP Violation Searches at the Fermilab Short Baseline Neutrino Facility
Creators: name: Cianci, Davio
name: Furmanski, Andy
name: Karagiorgi, Georgia
name: Ross-Lonergan, Mark
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the ability of the Short Baseline Neutrino (SBN) experimental program at Fermilab to test the globally-allowed (3+$N$) sterile neutrino oscillation parameter space. We explicitly consider the globally-allowed parameter space for the (3+1), (3+2), and (3+3) sterile neutrino oscillation scenarios. We find that SBN can probe with $5σ$ sensitivity more than 85\%, 95\% and 55\% of the parameter space currently allowed at 99\% confidence level for the (3+1), (3+2) and (3+3) scenarios, respectively. In the case of the (3+2) and (3+3) scenarios, CP-violating phases appear in the oscillation probability terms, leading to observable differences in the appearance probabilities of neutrinos and antineutrinos. We explore SBN's sensitivity to those phases for the (3+2) scenario through the currently planned neutrino beam running, and investigate potential improvements through additional antineutrino beam running. We show that, if antineutrino exposure is considered, for maximal values of the (3+2) CP-violating phase $ϕ_{54}$, SBN could be the first experiment to directly observe $\sim 2σ$ hints of CP violation associated with an extended lepton sector.
description: 19 pages, 21 figures
From Precursor/Stem Cells To Cordocytic Phenotypes In The Skin
Creators: name: Pais V
name: Pais E
Publisher: name: figshare
Year: 2018
Subjects: subject: 110708 Transplantation Immunology
subject: FOS: Clinical medicine

description: This cytohistopathological study was performed to have a better knowledge of the continuum of cellular events, from mesenchymal stem cells to mature cordocytic phenotypes with their morphological heterogeneity and multiple functions in the human skin. We used light microscopy, as well as transmission and scanning electron microscopy to study multiple tissue fragments obtained by skin biopsy from post-burn tissue, surrounding superficial temporal artery, and skin, in cases with urticaria pigmentosa, Fabry’s diffuse angiokeratoma, allergic vasculitis, hypodermitis, as well as basocellular nevomatosis and basocellular carcinoma. Our observations proved that the cordocytes appear from precursor/stem cells only outside the pericytes in the case of nascent dermal vessels, or from mesenchymal cells of the connective tissue surrounding superficial temporal artery within their niches, and they are responsible for multiple functions, especially protective for vessels and nerves in the reticular dermis. Their spatial and temporal interactions, either with each other or with another phenotype, undifferentiated or differentiated cells, and their implications in skin diseases, with changing phenotypes, position, and number, merit much more interest in further comprehensive studies. Our results showed that these protective interstitial cells promote useful interactions, influencing differentiation and fate of cells closely surrounded by them, as well as preventing or delaying some pathological processes.
Absolute Ages and Distances of 22 GCs using Monte Carlo Main-Sequence Fitting
Creators: name: O'Malley, Erin M.
name: Gilligan, Christina
name: Chaboyer, Brian
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The recent Gaia Data Release 1 of stellar parallaxes provides ample opportunity to find metal-poor main-sequence stars with precise parallaxes. We select 21 such stars with parallax uncertainties better than $σ_π/π\leq0.10$ and accurate abundance determinations suitable for testing metal-poor stellar evolution models and determining the distance to Galactic globular clusters. A Monte Carlo analysis was used, taking into account uncertainties in the model construction parameters, to generate stellar models and isochrones to fit to the calibration stars. The isochrones which fit the calibration stars best were then used to determine the distances and ages of 22 globular clusters with metallicities ranging from -2.4 dex to -0.7 dex. We find distances with an average uncertainty of 0.15 mag and absolute ages ranging from 10.8 - 13.6 Gyr with an average uncertainty of 1.6 Gyr. Using literature proper motion data we calculate orbits for the clusters finding six that reside within the Galactic disk/bulge while the rest are considered halo clusters. We find no strong evidence for a relationship between age and Galactocentric distance, but we do find a decreasing age-[Fe/H] relation.
description: 17 pages, 8 tables, 6 figures, accepted in ApJ
Induced spin-triplet pairing in the coexistence state of antiferromagnetism and singlet superconductivity: collective modes and microscopic properties
Creators: name: Almeida, Dalson Eloy
name: Fernandes, Rafael M.
name: Miranda, Eduardo
Publisher: name: arXiv
Year: 2017
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The close interplay between superconductivity and antiferromagnetism in several quantum materials can lead to the appearance of an unusual thermodynamic state in which both orders coexist microscopically, despite their competing nature. A hallmark of this coexistence state is the emergence of a spin-triplet superconducting gap component, called $π$-triplet, which is spatially modulated by the antiferromagnetic wave-vector, reminiscent of a pair-density wave. In this paper, we investigate the impact of these $π$-triplet degrees of freedom on the phase diagram of a system with competing antiferromagnetic and superconducting orders. Although we focus on a microscopic two-band model that has been widely employed in studies of iron pnictides, most of our results follow from a Ginzburg-Landau analysis, and as such should be applicable to other systems of interest, such as cuprates and heavy fermions. The Ginzburg-Landau functional reveals not only that the $π$-triplet gap amplitude couples tri-linearly with the singlet gap amplitude and the staggered magnetization magnitude, but also that the $π$-triplet $d$-vector couples linearly with the magnetization direction. While in the mean field level this coupling forces the $d$-vector to align parallel or anti-parallel to the magnetization, in the fluctuation regime it promotes two additional collective modes - a Goldstone mode related to the precession of the $d$-vector around the magnetization and a massive mode, related to the relative angle between the two vectors, which is nearly degenerate with a Leggett-like mode associated with the phase difference between the singlet and triplet gaps. We also investigate the impact of magnetic fluctuations on the superconducting-antiferromagnetic phase diagram, showing that due to their coupling with the $π$-triplet order parameter, the coexistence region is enhanced.
description: 13 pages, 4 figures
Ranunculus bulbosus var. corsicus Briq.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus bulbosus
Ranunculus bulbosus var. corsicus briq.

description: Ranunculus bulbosus var. corsicus Briq., Prodr. Fl. Corse 1: 621. 1910.
Lectotypus (hic designatus): FRANCE. Corse: entre le col de Santa Lucia et Luri (Cap Corse), 100 m, 26.IV.1907, Briquet, Saint-Yves & Cavillier 70 (G-BU [G00830056]!). Syntypi: (G-BU [G00830057, G00830058]!).
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 69, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
How many scientific papers are mentioned in policy-related documents? An empirical investigation using Web of Science and Altmetric data
Creators: name: Haunschild, Robin
name: Bornmann, Lutz
Publisher: name: arXiv
Year: 2016
Subjects: subject: Digital Libraries (cs.DL)
subject: FOS: Computer and information sciences

description: In this short communication, we provide an overview of a relatively newly provided source of altmetrics data which could possibly be used for societal impact measurements in scientometrics. Recently, Altmetric - a start-up providing publication level metrics - started to make data for publications available which have been mentioned in policy-related documents. Using data from Altmetric, we study how many papers indexed in the Web of Science (WoS) are mentioned in policy-related documents. We find that less than 0.5% of the papers published in different subject categories are mentioned at least once in policy-related documents. Based on our results, we recommend that the analysis of (WoS) publications with at least one policy-related mention is repeated regularly (annually). Mentions in policy-related documents should not be used for impact measurement until new policy-related sites are tracked.
description: 14 pages, 3 tables
Delay in recovery of the Antarctic ozone hole from unexpected CFC-11 emissions.
Creators: name: Dhomse, S S
name: Feng, W
name: Montzka, S A
name: Hossaini, R
name: Keeble, J
name: Pyle, J A
name: Daniel, J S
name: Chipperfield, M P
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019

description: The Antarctic ozone hole is decreasing in size but this recovery will be affected by atmospheric variability and any unexpected changes in chlorinated source gas emissions. Here, using model simulations, we show that the ozone hole will largely cease to occur by 2065 given compliance with the Montreal Protocol. If the unusual meteorology of 2002 is repeated, an ozone-hole-free-year could occur as soon as the early 2020s by some metrics. The recently discovered increase in CFC-11 emissions of ~ 13 Gg yr-1 may delay recovery. So far the impact on ozone is small, but if these emissions indicate production for foam use much more CFC-11 may be leaked in the future. Assuming such production over 10 years, disappearance of the ozone hole will be delayed by a few years, although there are significant uncertainties. Continued, substantial future CFC-11 emissions of 67 Gg yr-1 would delay Antarctic ozone recovery by well over a decade.
Die Wirkung des Puppenspiels in der Psychomotoriktherapie Fallstudie bei einem sozial unsicheren Kind
Creators: name: Muntwyler-Engelhard, Cornelia
Publisher: name: Zenodo
Year: 2017
Subjects: Psychomotorik
Psychomotoriktherapie
Figurentheater
Bachelorarbeit

description: In dieser Fallstudie wurde der therapeutische Prozess eines 5 Jahre 8 Monate alten Mäd-chens mit einer sozialen Unsicherheit untersucht, das sich vor allem bei neuen motorischen Anforderungen oft ganz verweigerte. Bei einer schwierigen Kontaktaufnahme mit dem Kind zeigte sich nach Einbezug von Handpuppen in die Therapie eine schnelle Verbesserung des kommunikativen und des motorischen Verhaltens. Ziel dieser Untersuchung war es, die Faktoren zu eruieren, welche der Wirksamkeit der Puppen zugrunde liegen. Die Videoaufnahmen von drei aufeinanderfolgenden Lektionen ab Beginn des Einsatzes der Handpuppentherapie wurden transkribiert, und der therapeutisch-kommunikative sowie der motorische Lernprozess analysiert. Die Analyse zeigt, dass die Puppen mittels Schaffen der nötigen Distanz als Intermediärobjekt und der Stimmungsaufheiterung die therapeutische Beziehung erleichtert haben. Die Handpuppen ermöglichten auch eine intensive Therapie mittels Modelllernen und eine Stärkung der Selbstwirksamkeitserwartung des Kindes.