cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
End of inflation, oscillons and matter-antimatter asymmetry
Creators: name: Lozanov, Kaloian D.
name: Amin, Mustafa A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: The dynamics at the end of inflation can generate an asymmetry between particles and anti-particles of the inflaton field. This asymmetry can be transferred to baryons via decays, generating a baryon asymmetry in our Universe. We explore this idea in detail for a complex inflaton governed by an observationally consistent -"flatter than quadratic"- potential with a weakly broken global U(1) symmetry. We find that most of the inflaton asymmetry is locked in non-topological soliton like configurations (oscillons) produced copiously at the end of inflation. These solitons eventually decay into baryons and generate the observed matter-antimatter asymmetry for a range of model parameters. Through a combination of three dimensional lattice simulations and a detailed linearized analysis, we show how the inflaton asymmetry depends on the fragmentation, the magnitude of the symmetry breaking term and initial conditions at the end of inflation. We discuss the final decay into baryons, but leave a detailed analysis of the inhomogeneous annihilation, reheating and thermalization to future work. As part of our work, we pay particular attention to generating multifield initial conditions for the field fluctuations (including metric perturbations) at the end of inflation for lattice simulations.
description: 19 pages, 9 figures. v3: references added and minor changes in text. Published in Phys. Rev. D
KIF13B-mediated VEGFR2 trafficking is essential for vascular leakage and metastasis in vivo
Creators: name: Waters, Stephen B
name: Dominguez, Joseph R
name: Cho, Hyun-Dong
name: Sarich, Nicolene A
name: Malik, Asrar
name: Yamada, Kaori
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: VEGF-A induces vascular leakage and angiogenesis via activating the cell surface localized receptor VEGF receptor 2 (VEGFR2). The amount of available VEGFR2 at the cell surface is however tightly regulated by trafficking of VEGFR2 by kinesin family 13 B (KIF13B), a plus-end kinesin motor, to the plasma membrane of endothelial cells (ECs). Competitive inhibition of interaction between VEGFR2 and KIF13B by a peptide kinesin-derived angiogenesis inhibitor (KAI) prevented pathological angiogenesis in models of cancer and eye disease associated with defective angiogenesis. Here, we show the protective effects of KAI in VEGF-A-induced vascular leakage and cancer metastasis. Using an EC-specific KIF13B knockout (Kif13b iECKO ) mouse model, we demonstrated the function of EC expressed KIF13B in mediating VEGF-A-induced vascular leakage, angiogenesis, tumor growth, and cancer metastasis. Thus, KIF13B-mediated trafficking of VEGFR2 to the endothelial surface has an essential role in pathological angiogenesis induced by VEGF-A, and is therefore a potential therapeutic target.
Non-perturbative Renormalization of Four-Fermion Operators Relevant to $B_K$ with Staggered Quarks
Creators: name: Jeong, Hwancheol
name: Kim, Jangho
name: Kim, Jongjeong
name: Lee, Weonjong
name: Pak, Jeonghwan
name: Park, Sungwoo
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We present preliminary results of matching factors of the four-fermion operators relevant to $B_K$, which are obtained using the non-perturbative renormalization (NPR) method in the RI-MOM scheme with HYP-smeared improved staggered fermions. We use the MILC asqtad coarse ($a \cong 0.12\,$fm) ensembles with $20^3 \times 64$ geometry and $am_{\ell}/am_s = 0.01/0.05$. We compare NPR results with those of one-loop perturbative matching.
description: 7 pages, 2 figures, Lattice 2014 proceeding, references updated
Simulating AIA observations of a flux rope ejection
Creators: name: Pagano, Paolo
name: Mackay, Duncan H.
name: Poedts, Stefaan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Extreme ultraviolet (EUV) images from the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamic Observatory (SDO) are providing new insights into the early phase of CME evolution. Observations now show the ejection of magnetic flux ropes from the solar corona and how they evolve into CMEs. These observations are difficult to interpret in terms of basic physical mechanisms and quantities. To fully understand CMEs we need to compare equivalent quantities derived from both observations and theoretical models. To this end we aim to produce synthesised AIA observations from simluations of a flux rope ejection. To carry this out we include the role of thermal conduction and radiative losses, both of which are important for determining the temperature distribution of the solar corona during a CME. We perform a simulation where a flux rope is ejected from the solar corona. From the density and temperature of the plasma in the simulation we synthesise AIA observations. The emission is then integrated along the line of sight using the instrumental response function of AIA. We sythesise observations of AIA in the channels at 304 A, 171 A, 335 A, and 94 A. The synthesised observations show a number of features similar to actual observations and in particular reproduce the general development of CMEs in the low corona as observed by AIA. In particular we reproduce an erupting and expanding arcade in the 304 A and 171 A channels with a high density core. The ejection of a flux rope reproduces many of the features found in the AIA observations. This work is therefore a step forward in bridging the gap between observations and models, and can lead to more direct interpretations of EUV observations in terms of flux rope ejections. We plan to improve the model in future studies in order to perform a more quantitative comparison.
Replication data for "A Perpetual (Liberal) Peace? An Empirical Assessment of an Enduring Peacebuilding Model".
Creators: name: Sguazzini, Mattia
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 440402
subject: Humanitarian disasters, conflict and peacebuilding

description: Replication data for the paper "A perpetual (liberal) peace? An empirical assessment of an enduring peacebuilding model".
If you use them, please cite:
Giulio Levorato & Mattia Sguazzini (2023) A Perpetual (Liberal) Peace? An Empirical Assessment of an Enduring Peacebuilding Model, International Peacekeeping, DOI: 10.1080/13533312.2023.2255523
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer.
Creators: name: Sugimoto, Yoichiro
name: Ratcliffe, Peter J
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: Biochemistry & Proteomics
Metabolism
Cell Biology
Signalling & Oncogenes

description: Hypoxia inducible factor (HIF) and mammalian target of rapamycin (mTOR) pathways orchestrate responses to oxygen and nutrient availability. These pathways are frequently dysregulated in cancer, but their interplay is poorly understood, in part because of difficulties in simultaneous measurement of global and mRNA-specific translation. Here, we describe a workflow for measurement of ribosome load of mRNAs resolved by their transcription start sites (TSSs). Its application to kidney cancer cells reveals extensive translational reprogramming by mTOR, strongly affecting many metabolic enzymes and pathways. By contrast, global effects of HIF on translation are limited, and we do not observe reported translational activation by HIF2A. In contrast, HIF-dependent alterations in TSS usage are associated with robust changes in translational efficiency in a subset of genes. Analyses of the interplay of HIF and mTOR reveal that specific classes of HIF1A and HIF2A transcriptional target gene manifest different sensitivity to mTOR, in a manner that supports combined use of HIF2A and mTOR inhibitors in treatment of kidney cancer.
Leveraging local identity-by-descent increases the power of case/control GWAS with related individuals
Creators: name: Sampson, Joshua N.
name: Wheeler, Bill
name: Li, Peng
name: Shi, Jianxin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Applications (stat.AP)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Large case/control Genome-Wide Association Studies (GWAS) often include groups of related individuals with known relationships. When testing for associations at a given locus, current methods incorporate only the familial relationships between individuals. Here, we introduce the chromosome-based Quasi Likelihood Score (cQLS) statistic that incorporates local Identity-By-Descent (IBD) to increase the power to detect associations. In studies robust to population stratification, such as those with case/control sibling pairs, simulations show that the study power can be increased by over 50%. In our example, a GWAS examining late-onset Alzheimer's disease, the $p$-values among the most strongly associated SNPs in the APOE gene tend to decrease, with the smallest $p$-value decreasing from $1.23\times10^{-8}$ to $7.70\times 10^{-9}$. Furthermore, as a part of our simulations, we reevaluate our expectations about the use of families in GWAS. We show that, although adding only half as many unique chromosomes, genotyping affected siblings is more efficient than genotyping randomly ascertained cases. We also show that genotyping cases with a family history of disease will be less beneficial when searching for SNPs with smaller effect sizes.
description: Published in at http://dx.doi.org/10.1214/14-AOAS715 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Dissortative From the Outside, Assortative From the Inside: Social Structure and Behavior in the Industrial Trade Network
Creators: name: Kelman, Guy
name: Brée, David S.
name: Manes, Eran
name: Lamieri, Marco
name: Golo, Natasa
name: Solomon, Sorin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: It is generally accepted that neighboring nodes in financial networks are negatively assorted with respect to the correlation between their degrees. This feature would play an important 'damping' role in the market during downturns (periods of distress) since this connectivity pattern between firms lowers the chances of auto-amplifying (the propagation of) distress. In this paper we explore a trade-network of industrial firms where the nodes are suppliers or buyers, and the links are those invoices that the suppliers send out to their buyers and then go on to present to their bank for discounting. The network was collected by a large Italian bank in 2007, from their intermediation of the sales on credit made by their clients. The network also shows dissortative behavior as seen in other studies on financial networks. However, when looking at the credit rating of the firms, an important attribute internal to each node, we find that firms that trade with one another share overwhelming similarity. We know that much data is missing from our data set. However, we can quantify the amount of missing data using information exposure, a variable that connects social structure and behavior. This variable is a ratio of the sales invoices that a supplier presents to their bank over their total sales. Results reveal a non-trivial and robust relationship between the information exposure and credit rating of a firm, indicating the influence of the neighbors on a firm's rating. This methodology provides a new insight into how to reconstruct a network suffering from incomplete information.
description: 10 pages, 10 figures, To appear in conference proceedings of the IEEE: HICSS-48
Replication data for "A Perpetual (Liberal) Peace? An Empirical Assessment of an Enduring Peacebuilding Model"
Creators: name: Sguazzini, Mattia
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 440402
subject: Humanitarian disasters, conflict and peacebuilding

description: Replication data for the paper "A perpetual (liberal) peace? An empirical assessment of an enduring peacebuilding model"
Stable, Robust and Super Fast Reconstruction of Tensors Using Multi-Way Projections
Creators: name: Caiafa, Cesar F.
name: Cichocki, Andrzej
Publisher: name: arXiv
Year: 2014
Subjects: subject: Information Theory (cs.IT)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences

description: In the framework of multidimensional Compressed Sensing (CS), we introduce an analytical reconstruction formula that allows one to recover an $N$th-order $(I_1\times I_2\times \cdots \times I_N)$ data tensor $\underline{\mathbf{X}}$ from a reduced set of multi-way compressive measurements by exploiting its low multilinear-rank structure. Moreover, we show that, an interesting property of multi-way measurements allows us to build the reconstruction based on compressive linear measurements taken only in two selected modes, independently of the tensor order $N$. In addition, it is proved that, in the matrix case and in a particular case with $3$rd-order tensors where the same 2D sensor operator is applied to all mode-3 slices, the proposed reconstruction $\underline{\mathbf{X}}_τ$ is stable in the sense that the approximation error is comparable to the one provided by the best low-multilinear-rank approximation, where $τ$ is a threshold parameter that controls the approximation error. Through the analysis of the upper bound of the approximation error we show that, in the 2D case, an optimal value for the threshold parameter $τ=τ_0 > 0$ exists, which is confirmed by our simulation results. On the other hand, our experiments on 3D datasets show that very good reconstructions are obtained using $τ=0$, which means that this parameter does not need to be tuned. Our extensive simulation results demonstrate the stability and robustness of the method when it is applied to real-world 2D and 3D signals. A comparison with state-of-the-arts sparsity based CS methods specialized for multidimensional signals is also included. A very attractive characteristic of the proposed method is that it provides a direct computation, i.e. it is non-iterative in contrast to all existing sparsity based CS algorithms, thus providing super fast computations, even for large datasets.
description: Submitted to IEEE Transactions on Signal Processing
Integrable approach to simple exclusion processes with boundaries. Review and progress
Creators: name: Crampe, N.
name: Ragoucy, E.
name: Vanicat, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Theory (hep-th)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: We study the matrix ansatz in the quantum group framework, applying integrable systems techniques to statistical physics models. We start by reviewing the two approaches, and then show how one can use the former to get new insight on the latter. We illustrate our method by solving a model of reaction-diffusion. An eigenvector for the transfer matrix for the XXZ spin chain with non-diagonal boundary is also obtained using a matrix ansatz.
description: 44 pages
Wood Anatomy Image and Program for Wood Identification
Creators: name: Minh, Trieu Nguyen
name: Truong, Thinh Nguyen
Publisher: name: Zenodo
Year: 2022
Subjects: Identifying wood, Anatomical wood, Hybrid model, CNN-RF, Automatic identification

description: This is a part of the dataset about anatomy wood and a subprogram is used for wood identification based on anatomy images using a hydride model. Theories are introduced in our manuscript. In our study, wood anatomical images are collected then they are used to train for the hybrid deep neural network model, and, these images can be used to determine the properties of woods. An automatic wood identification system is proposed and a dataset of 50 wood species is also established. The last layers of the traditional convolutional neural network (CNN) are usually the softmax functions with dense layers. These layers contain the most parameters that affect the speed model. In this study, a hybrid of convolutional neural network and random forest model (CNN-RF model) is introduced to wood identification with the accuracy of the model higher than 98% and it is higher more than 15% compared to the traditional model. This shows the excellent adaptability of the hybrid model in wood identification based on anatomical images. It also facilitates further investigations of wood cells and has implications for wood science.
THE INFLUENCE OF PARENT-CHILD RELATIONSHIP ON THE FORMATION OF CHILDREN'S BEHAVIOR
Creators: name: Yunusova, Gozal
Publisher: name: Zenodo
Year: 2023

description: This article covers the topic of the influence of parents and children on the formation of children's behavior, in which the analysis of the scientific and theoretical views of pedagogues and psychologists on the topic of the role of parents in the family and its psychological influence on the formation of children's behavior, as well as the conclusion and recommendations are written.
VEGFR2 Trafficking by KIF13B Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration
Creators: name: Waters, Stephen B
name: Zhou, Christopher
name: Nguyen, Tara
name: Zelkha, Ruth
name: Lee, Hyun
name: Kazlauskas, Andrius
name: Rosenblatt, Mark
name: Malik, Asrar
name: Yamada, Kaori
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: Purpose: Vascular endothelial growth factor (VEGF) and its receptor VEGFR2 are promising therapeutic targets for wet age-related macular degeneration (AMD). As a topically applicable option, we developed the peptide KAI to selectively interfere with VEGFR2 trafficking to the cell surface where it receives VEGF. This study sought to determine the efficacy of KAI in the mouse model of choroidal neovascularization (CNV). Methods: The specificity of KAI was tested by surface plasmon resonance. The drug delivery was analyzed by cryosection and the ELISA after treatment of KAI eyedrop to the mouse eyes. For the laser-induced CNV model, mice with laser-induced ruptures in Bruch's membrane received daily treatment of KAI eyedrop or control peptide. The other groups of mice received intravitreal injection of anti-VEGF or IgG control. After two weeks, CNV was quantified and compared. Results: First, we showed the specificity and high affinity of KAI to VEGFR2. Next, biodistribution revealed successful delivery of KAI eyedrop to the back of the mouse eyes. KAI significantly reduced the disease progression in laser-induced CNV. The comparison with current therapy suggests that KAI eyedrop is as effective as current therapy to prevent CNV in wet AMD. Moreover, the genetic deletion of a kinesin KIF13B, which mediates VEGFR2 trafficking to the cell surface, confirmed the pivotal role of KIF13B in disease progression of wet AMD and neovascularization from choroidal vessels. Conclusions: Taken together, pharmacologic inhibition and genetic deletion complementarily suggest the therapeutic possibility of targeting VEGFR2 trafficking to inhibit pathological angiogenesis in wet AMD.
Quantum phase transitions in the noncommutative Dirac Oscillator
Creators: name: Panella, O.
name: Roy, P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the (2+1) dimensional Dirac oscillator in a homogeneous magnetic field in the non-commutative plane. It is shown that the effect of non-commutativity is twofold: $i$) momentum non commuting coordinates simply shift the critical value ($B_{\text{cr}}$) of the magnetic field at which the well known left-right chiral quantum phase transition takes place (in the commuting phase); $ii$) non-commutativity in the space coordinates induces a new critical value of the magnetic field, $B_{\text{cr}}^*$, where there is a second quantum phase transition (right-left), --this critical point disappears in the commutative limit--. The change in chirality associated with the magnitude of the magnetic field is examined in detail for both critical points. The phase transitions are described in terms of the magnetisation of the system. Possible applications to the physics of silicene and graphene are briefly discussed.
description: 26 pages, two figures. Editorial improvements, few references added. Version accepted by Physical Review A
title: Nutzung von Patient-Reported Outcome Measures (PROMs)  im deutschsprachigen Raum
title: Ergebnisse einer Online-Befragung
titleType: Subtitle
Creators: name: Steinbeck, Viktoria
name: Ernst, Sophie-Christin
name: Burger, Michaela
name: Pross, Christoph
Publisher: name: Bertelsmann Stiftung
Year: 2022
Subjects: Gesundheitssystem
Patient
Medizinische Versorgung

description: Wie werden patientenberichtete Gesundheitsdaten (PROMs) heute genutzt? Welche konkreten Hürden behindern die breitflächige Implementierung und welche Faktoren sind besonders förderlich? Dazu fand von Juli bis Dezember 2021 eine Online-Befragung unter PROM-Anwenderinnen und -Anwendern im deutschsprachigen Raum statt. Der vorliegende Ergebnisbericht „Nutzung von Patient-Reported Outcome Measures (PROMs) im deutschsprachigen Raum“ liefert interessante Erkenntnisse aus der Praxis und Ansatzpunkte für nächste Schritte auf dem Weg zu einer breiteren Implementierung von PROMs.
Mapas Participativos de Riesgo Volcánico: una experiencia de co-producción entre científicos y comunidades en Colombia.
Creators: name: Rocha-Gutiérrez, Felipe
Publisher: name: Zenodo
Year: 2022
Subjects: Riesgo Volcánico; Geocientífico; Comunicación Pública de Ciencia; Apropiación Social de Ciencia y Tecnología

description: Presentación que rinde cuenta de manera panorámica del proceso de creación de una pieza comunicativa denominada "mapas participativos de riesgo volcánico", que surge en el marco de la Estrategia Nacional de Comunicación del Riesgo Volcánico en Colombia en 2016. Su propósito es el de saldar una brecha de comunicación entre expertos geo-científicos y "públicos legos" que son comunidades indígenas y campesinas de los Departamentos de Caldas, Nariño, Cauca y Tolima en Colombia.
A Bayesian nonparametric mixture model for selecting genes and gene subnetworks
Creators: name: Zhao, Yize
name: Kang, Jian
name: Yu, Tianwei
Publisher: name: arXiv
Year: 2014
Subjects: subject: Applications (stat.AP)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: It is very challenging to select informative features from tens of thousands of measured features in high-throughput data analysis. Recently, several parametric/regression models have been developed utilizing the gene network information to select genes or pathways strongly associated with a clinical/biological outcome. Alternatively, in this paper, we propose a nonparametric Bayesian model for gene selection incorporating network information. In addition to identifying genes that have a strong association with a clinical outcome, our model can select genes with particular expressional behavior, in which case the regression models are not directly applicable. We show that our proposed model is equivalent to an infinity mixture model for which we develop a posterior computation algorithm based on Markov chain Monte Carlo (MCMC) methods. We also propose two fast computing algorithms that approximate the posterior simulation with good accuracy but relatively low computational cost. We illustrate our methods on simulation studies and the analysis of Spellman yeast cell cycle microarray data.
description: Published in at http://dx.doi.org/10.1214/14-AOAS719 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Newton algorithm for Hamiltonian characterization in quantum control
Creators: name: Ndong, M.
name: Salomon, J.
name: Sugny, D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a Newton algorithm to characterize the Hamiltonian of a quantum system interacting with a given laser field. The algorithm is based on the assumption that the evolution operator of the system is perfectly known at a fixed time. The computational scheme uses the Crank-Nicholson approximation to explicitly determine the derivatives of the propagator with respect to the Hamiltonians of the system. In order to globalize this algorithm, we use a continuation method that improves its convergence properties. This technique is applied to a two-level quantum system and to a molecular one with a double-well potential. The numerical tests show that accurate estimates of the unknown parameters are obtained in some cases. We discuss the numerical limits of the algorithm in terms of basin of convergence and non uniqueness of the solution.
description: 18 pages, 7 figures
Voxel-level mapping of tracer kinetics in PET studies: A statistical approach emphasizing tissue life tables
Creators: name: O'Sullivan, Finbarr
name: Muzi, Mark
name: Mankoff, David A.
name: Eary, Janet F.
name: Spence, Alexander M.
name: Krohn, Kenneth A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Applications (stat.AP)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Most radiotracers used in dynamic positron emission tomography (PET) scanning act in a linear time-invariant fashion so that the measured time-course data are a convolution between the time course of the tracer in the arterial supply and the local tissue impulse response, known as the tissue residue function. In statistical terms the residue is a life table for the transit time of injected radiotracer atoms. The residue provides a description of the tracer kinetic information measurable by a dynamic PET scan. Decomposition of the residue function allows separation of rapid vascular kinetics from slower blood-tissue exchanges and tissue retention. For voxel-level analysis, we propose that residues be modeled by mixtures of nonparametrically derived basis residues obtained by segmentation of the full data volume. Spatial and temporal aspects of diagnostics associated with voxel-level model fitting are emphasized. Illustrative examples, some involving cancer imaging studies, are presented. Data from cerebral PET scanning with $^{18}$F fluoro-deoxyglucose (FDG) and $^{15}$O water (H2O) in normal subjects is used to evaluate the approach. Cross-validation is used to make regional comparisons between residues estimated using adaptive mixture models with more conventional compartmental modeling techniques. Simulations studies are used to theoretically examine mean square error performance and to explore the benefit of voxel-level analysis when the primary interest is a statistical summary of regional kinetics. The work highlights the contribution that multivariate analysis tools and life-table concepts can make in the recovery of local metabolic information from dynamic PET studies, particularly ones in which the assumptions of compartmental-like models, with residues that are sums of exponentials, might not be certain.
description: Published in at http://dx.doi.org/10.1214/14-AOAS732 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Limits on Vectorlike Leptons from Searches for Anomalous Production of Multi-Lepton Events
Creators: name: Dermisek, Radovan
name: Hall, Jonathan P.
name: Lunghi, Enrico
name: Shin, Seodong
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We consider extensions of the Standard Model by vectorlike leptons and set limits on a new charged lepton, $e_4^\pm$, using the ATLAS search for anomalous production of multi-lepton events. It is assumed that only one Standard Model lepton, namely the muon, dominantly mixes with vectorlike leptons resulting in possible decays $e_4^\pm \to W^\pm ν_μ$, $e_4^\pm \to Zμ^\pm$, and $e_4^\pm \to h μ^\pm$. We derive generally applicable limits on the new lepton treating the branching ratios for these processes as free variables. We further interpret the general limits in two scenarios with $e_4^\pm$ originating predominantly from either the $SU(2)$ doublet or the $SU(2)$ singlet. The doublet case is more constrained as a result of larger production cross-section and extra production processes $e_4^\pm ν_4$ and $ν_4ν_4$ in addition to $e_4^+ e_4^-$, where $ν_4$ is a new neutral state accompanying $e_4$. We find that some combinations of branching ratios are poorly constrained, whereas some are constrained up to masses of more than 500 GeV. In the doublet case, assuming BR$(ν_4\rightarrow Wμ) = 1$, all masses below about 300 GeV are ruled out. Even if this condition is relaxed and additional decay modes, $ν_4 \to Z ν_μ$ and $ν_4 \to h ν_μ$, are allowed, below the Higgs threshold still almost all of the parameter space (of independent branching ratios) is ruled out. Nevertheless, even assuming the maximal production cross-section, which coincides with the doublet case, the new charged lepton can still be as light as the LEP-II limit allows. We discuss several possible improvements of current experimental analyses that would dramatically reduce the allowed parameter space, even with current data.
description: 24 pages, 11 figures
Principios de la Política de Acceso Abierto de la UNal
Creators: name: Pavas, Andrés
name: Sánchez, Johanna
name: Cardona, Francisco
name: Amaya, Alberto
name: Poveda, Juan Francisco
name: Rodríguez, Robinson
Publisher: name: Zenodo
Year: 2022
Subjects: Acceso Abierto
Ciencia Abierta
Autonomía universitaria
Política institucional

description: La Universidad Nacional de Colombia está construyendo una Política de Acceso Abierto que mira al futuro de Colombia en un escenario de Ciencia Abierta. La comunicación sin restricciones ni costos para lectores y autores ha sido parte de la identidad Institucional, pero hay mucho por mejorar. El propósito de esta presentación es compartir la perspectiva de la Universidad Nacional de Colombia sobre el Acceso Abierto con la comunidad participante en el Congreso Iberoamericano de Ciencia Abierta, de forma que se planteen discusiones sobre nuestro enfoque.
Hadronization systematics and top mass reconstruction
Creators: name: Corcella, Gennaro
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: I discuss a few issues related to the systematic error on the top mass measurement at hadron colliders, due to hadronization effects. Special care is taken about the impact of bottom-quark fragmentation in top decays, especially on the reconstruction relying on final states with leptons and J/psi in the dilepton channel. I also debate the relation between the measured mass and its theoretical definition, and report on work in progress, based on the Monte Carlo simulation of fictitious top-flavoured hadrons, which may shed light on this issue and on the hadronization systematics.
description: 7 pages, 2 figures, 1 table. Talk given at QCD@Work 2014, Giovinazzo, Italy, June 2014
Probing the nuclear star cluster of galaxies with ELTs
Creators: name: Gullieuszik, M.
name: Greggio, L.
name: Falomo, R.
name: Schreiber, L.
name: Uslenghi, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The unprecedented sensitivity and spatial resolution of next generation ground-based extremely large telescopes (ELTs) will open a completely new window on the study of resolved stellar populations. In this paper we study the feasibility of the analysis of nuclear star cluster (NSC) stellar populations with ELTs. To date, NSC stellar population studies are based on the properties of their integrated light. NSC are in fact observed as unresolved sources even with the HST. We explore the possibility to obtain direct estimates of the age of NSC stellar populations from photometry of main-sequence turn-off stars. We simulated ELT observations of NSCs at different distances and with different stellar populations. Photometric measurements on each simulated image were analysed in detail and results about photometric accuracy and completeness are reported here. We found that the main-sequence turn-off is detectable -and therefore the age of stellar populations can be directly estimated- up to 2Mpc for old, up to 3 Mpc for intermediate-age and up to 4-5 Mpc for young stellar populations. We found that for this particular science case the performances of TMT and E-ELT are of comparable quality.
description: 11 pages, 11 figures. Accepted for publication in A&A
KIF13B - mediated VEGFR2 trafficking is essential for vascular leakage and metastasis in vivo
Creators: name: Waters, Stephen B
name: Dominguez, Joseph R
name: Cho, Hyun-Dong
name: Sarich, Nicolene A
name: Malik, Asrar B
name: Yamada, Kaori
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: VEGF-A induces vascular leakage and angiogenesis via activating the cell surface localized receptor VEGF receptor 2 (VEGFR2). The amount of available VEGFR2 at the cell surface is however tightly regulated by trafficking of VEGFR2 by kinesin family 13 B (KIF13B), a plus-end kinesin motor, to the plasma membrane of endothelial cells (ECs). Competitive inhibition of interaction between VEGFR2 and KIF13B by a peptide kinesin-derived angiogenesis inhibitor (KAI) prevented pathological angiogenesis in models of cancer and eye disease associated with defective angiogenesis. Here, we show the protective effects of KAI in VEGF-A-induced vascular leakage and cancer metastasis. Using an EC-specific KIF13B knockout (Kif13biECKO) mouse model, we demonstrated the function of EC expressed KIF13B in mediating VEGF-A-induced vascular leakage, angiogenesis, tumor growth, and cancer metastasis. Thus, KIF13B-mediated trafficking of VEGFR2 to the endothelial surface has an essential role in pathological angiogenesis induced by VEGF-A, and is therefore a potential therapeutic target.
Higher Spin Entanglement Entropy
Creators: name: Long, Jiang
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper, we develop a perturbation formulation to calculate the single interval higher spin R$\acute{e}$nyi and entanglement entropy for two dimensional conformal field theory with $\mathcal{W}_{\infty}(λ)$ symmetry. The system is at finite temperature and is deformed by higher spin chemical potential. We manage to compute higher spin R$\acute{e}$nyi entropy with various spin deformations up to order $\mathcal{O}(μ^2)$. For spin 3 deformation, we calculate exact higher spin R$\acute{e}$nyi entropy up to $\mathcal{O}(μ^4)$. When $λ=3$, in the large $c$ limit, we find perfect match with tree level holographic higher spin entanglement entropy up to order $μ^4$ obtained by the Wilson line prescription. We also find quantum corrections to higher spin entanglement entropy which is beyond tree level holographic results. The quantum correction is universal at order $μ^4$ in the sense that it is independent of $λ$. Our computation relies on a multi-valued conformal map from $n$-sheeted Riemann surface $\mathcal{R}_n$ to complex plane and correlation functions of primary fields on complex plane. The method can be applied to general conformal field theories with $\mathcal{W}$ symmetry.
description: 49 pages,1 figure, to be published in JHEP
D6.7 Monitoring Plan of the Digital Twin Instances
Creators: name: Galindo, Antoni
name: Ortega, Enric
name: Quintana, Antoni
name: Reyes, Guillermo
name: Borras, Mikel
name: Leão, Jorge
name: Porkka, Janne
name: Piira, Kalevi
Publisher: name: Zenodo
Year: 2021

description: This document explains the monitoring processes in the four pilots of the SPHERE project. It will also give an overview of which tools will be applied in each pilot. The document will focus on the tools that require data to be monitored. It will also go into detail on which variables (temperatures, consumptions, etc.) are going to be monitored, the frequency of the capture of these variables, and the equipment that is installed in the building in order to provide the values of these variables. Finally, is described the software, the gateways and the communication interfaces that allow all this information to be transmitted from the sensors and meters installed in the pilots to the Digital Twin Platform of IDP and VTT. These platforms will act as a repository of the captured variables. The tool providers will access these repositories to obtain the required information for the operation of their respective tools.
Quasi-Static 3D-Magnetic Field Evolution in Solar Active Region NOAA 11166 Associated with X1.5 Flare
Creators: name: Vemareddy, P.
name: Wiegelmann, T.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We study the quasi-static evolution of coronal magnetic fields constructed from the Non Linear Force Free Field (NLFFF) approximation aiming to understand the relation between the magnetic field topology and ribbon emission during an X1.5 flare in active region (AR) NOAA 11166. The flare with a quasi-elliptical, and two remote ribbons occurred on March 9, 2011 at 23:13UT over a positive flux region surrounded by negative flux at the center of the bipolar AR. Our analysis of the coronal magnetic structure with potential and NLFFF solutions unveiled the existence of a single magnetic null point associated with a fan-spine topology and is co-spatial with the hard X-ray source. The footpoints of the fan separatrix surface agree with the inner edge of the quasi-elliptical ribbon and the outer spine is linked to one of the remote ribbons. During the evolution, the slow footpoint motions stressed the fieldlines along the polarity inversion line and caused electric current layers in the corona around the fan separatrix surface. These current layers trigger magnetic reconnection as a consequence of dissipating currents, which are visible as cusped shape structures at lower heights. The reconnection process reorganised the magnetic field topology whose signatures are observed at the separatrices/QSL structure both in the photosphere and corona during the pre-to-post flare evolution. In agreement with previous numerical studies, our results suggest that the line-tied footpoint motions perturb the fan-spine system and cause null point reconnection, which eventually causes the flare emission at the footpoints of the fieldlines.
description: Accepted, 2014, The Astrophysical Journal
A recoil detector for the measurement of antiproton-proton elastic scattering at angles close to 90$^{\circ}$
Creators: name: Hu, Q.
name: Bechstedt, U.
name: Gillitzer, A.
name: Grzonka, D.
name: Khoukaz, A.
name: Klehr, F.
name: Lehrach, A.
name: Prasuhn, D.
name: Ritman, J.
name: Sefzick, T.
name: Stockmann, T.
name: Täschner, A.
name: Wuestner, P.
name: Xu, H.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The design and construction of a recoil detector for the measurement of recoil protons of antiproton-proton elastic scattering at scattering angles close to 90$^{\circ}$ are described. The performance of the recoil detector has been tested in the laboratory with radioactive sources and at COSY with proton beams by measuring proton-proton elastic scattering. The results of laboratory tests and commissioning with beam are presented. Excellent energy resolution and proper working performance of the recoil detector validate the conceptual design of the KOALA experiment at HESR to provide the cross section data needed to achieve a precise luminosity determination at the PANDA experiment.
description: 10 pages, 15 figures
Deep learning driven content-based image time-series retrieval in remote sensing archives
Creators: name: Vuran, Onat
name: Akcin, Oguzhan
name: Ravanbakhsh, Mahdyar
name: Sankur, Bülent
name: Demir, Begüm
Publisher: name: Technische Universität Berlin
Year: 2022
Subjects: subject: 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten
subject: content based time-series retrieval
subject: deep learning
subject: remote sensing
subject: learning systems
subject: satellites

description: The rapid evolution of satellite imaging systems has resulted in sharp increases of image archive volumes. Multitemporal images constitute a sizeable portion of these time-series databases. Accordingly, development of accurate content based time-series retrieval (CBTSR) methods in massive archives of RS images attracts much research interest. Given a user-defined query time series, CBTSR aims at identifying within a massive archive image time series that show characteristics similar to those of the query time series. In this paper, we focus our attention to CBTSR in pairs of RS images, aiming to search and retrieve bi-temporal image pairs containing changes similar to those modeled in the query. To this end, we introduce two deep learning-based methods in the framework of CBTSR. The first method, called deep change vector retrieval (DVCR), is based on selected deep features extracted from the change vector analysis. The second method, called autoencoder with early fusion (AEEF) uses an autoencoder architecture to recreate the time difference images and the latent codes produced by this network. Experimental results show the effectiveness of the proposed methods for CBTSR problems. The code of the proposed methods is available at: https://github.com/OnatV/ChangeRetrieval.
title: AGORA-EO: A unified ecosystem for earthobservation
title: A vision for boosting EO data literacy
titleType: Subtitle
Creators: name: Wall, Arne De
name: Deiseroth, Björn
name: Zacharatou, Eleni Tzirita
name: Quiané-Ruiz, Jorge-Arnulfo
name: Demir, Begüm
name: Markl, Volker
Publisher: name: Technische Universität Berlin
Year: 2021
Subjects: subject: 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten
subject: Big Data
subject: earth observation ecosystem
subject: federated analytics

description: Today’s EO exploitation platforms are limited to the processing functionalities and datasets they provide, and there is no single platform that provides all datasets of interest. Thus, it is crucial to enable cross-platform (federated) analytics to make EO technology easily accessible to everyone. We envision AgoraEO, an EO ecosystem for sharing, finding, composing, and executing EO assets, such as datasets, algorithms, and tools. Making AgoraEO a reality is challenging for several reasons, the main ones being that the ecosystem must provide interactive response times and operate seamlessly over multiple exploitation platforms. In this paper, we discuss the different challenges that AgoraEO poses as well as our ideas to tackle them. We believe that having an open, unified EO ecosystem would foster innovation and boost EO data literacy for the entire population.
First-principles study of the multi-mode anti-ferroelectric transition of PbZrO3
Creators: name: Iniguez, Jorge
name: Stengel, Massimiliano
name: Prosandeev, Sergey
name: Bellaiche, L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We have studied ab initio the phase transition in PbZrO3, a perovskite oxide usually presented as the prototypic anti-ferroelectric material. Our work reveals the crucial role that anti-ferrodistortive modes -- involving concerted rotations of the oxygen octahedra in the structure -- play in the transformation, as they select the observed anti-ferroelectric phase, among competing structural variants, via a cooperative trilinear coupling.
description: 5 pages with 3 figures embedded. More information at http://departments.icmab.es/leem/jorge
Modelling mass drug administration strategies for reducing scabies burden in Monrovia, Liberia
Creators: name: Tellioglu, N
name: Chisholm, Rebecca
name: Campbell, PT
name: Collinson, S
name: Timothy, J
name: Kollie, K
name: Zayzay, S
name: Devine, A
name: McVernon, J
name: Marks, M
name: Geard, N
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 3202
subject: Clinical sciences
classificationCode: 3204
subject: Immunology
subject: FOS: Clinical medicine
classificationCode: 4202
subject: Epidemiology

description: Scabies is a parasitic infestation with high global burden. Mass drug administrations (MDAs) are recommended for communities with a scabies prevalence of >10%. Quantitative analyses are needed to demonstrate the likely effectiveness of MDA recommendations. In this study, we developed an agent-based model of scabies transmission calibrated to demographic and epidemiological data from Monrovia. We used this model to compare the effectiveness of MDA scenarios for achieving scabies elimination and reducing scabies burden, as measured by time until recrudescence following delivery of an MDA and disability-adjusted-life-years (DALYs) averted. Our model showed that three rounds of MDA delivered at six-month intervals and reaching 80% of the population could reduce prevalence below 2% for three years following the final round, before recrudescence. When MDAs were followed by increased treatment uptake, prevalence was maintained below 2% indefinitely. Increasing the number of and coverage of MDA rounds increased the probability of achieving elimination and the number of DALYs averted. Our results suggest that acute reduction of scabies prevalence by MDA can support a transition to improved treatment access. This study demonstrates how modelling can be used to estimate the expected impact of MDAs by projecting future epidemiological dynamics and health gains under alternative scenarios.