cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Simulating the H2 content of high-redshift galaxies
Creators: name: Tomassetti, Matteo
name: Porciani, Cristiano
name: Romano-Diaz, Emilio
name: Ludlow, Aaron D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We introduce a sub-grid model for the non-equilibrium abundance of molecular hydrogen in cosmological simulations of galaxy formation. We improve upon previous work by accounting for the unresolved structure of molecular clouds in a phenomenological way which combines both observational and numerical results on the properties of the turbulent interstellar medium. We apply the model to a cosmological simulation of the formation of a Milky-Way-sized galaxy at z=2, and compare the results to those obtained using other popular prescriptions that compute the equilibrium abundance of H2. In these runs we introduce an explicit link between star formation and the local H2 abundance, and perform an additional simulation in which star formation is linked directly to the density of cold gas. In better agreement with observations, we find that the simulated galaxy produces less stars and harbors a larger gas reservoir when star formation is regulated by molecular hydrogen. In this case, the galaxy is composed of a younger stellar population as early star formation is inhibited in small, metal poor dark-matter haloes which cannot efficiently produce H2. The number of luminous satellites orbiting within the virial radius of the galaxy at z=2 is reduced by 10-30 per cent in models with H2-regulated star formation.
description: 18 pages, 12 figures. Accepted for publication in MNRAS
Boundary smoothness of analytic functions
Creators: name: O'Farrell, Anthony G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Complex Variables (math.CV)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 30E25, 30H99, 46J10

description: We consider the behaviour of holomorphic functions on a bounded open subset of the plane, satisfying a Lipschitz condition with exponent $α$, with $0
description: 14 pages. This revision corrects a misprint on p.12: In equation (3), $\alpha$ should have been $1-\alpha$. Also a misprint on page 14 in the formula for $R_a-L_a$. The validity of the argument is not affected and the result stands
EDINOBORSTVA
Creators: name: Kharkiv State Academy Of Physical Culture
Publisher: name: Zenodo
Year: 2019

description: The collection presents articles on the organization of the educational process in institutions of higher education, sports schools; improvement of training of athletes in modern conditions; state of physical, technical, tactical and psychological preparedness of athletes; the effectiveness of competitive indicators; organization of patriotic education of youth of Ukraine in the course of martial arts activities; perfection of the process of physical education of students using martial arts.

For post-graduate students, doctoral students, masters, trainers, athletes, teachers of educational institutions, teachers of secondary schools.
Top tautological group of $\mathcal M_{g,n}$
Creators: name: Buryak, A.
name: Shadrin, S.
name: Zvonkine, D.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: We describe the structure of the top tautological group in the cohomology of the moduli space of smooth genus $g$ curves with $n$ marked points.
description: Revised version: the paper is substantially reorganized, 30 pages, to appear in the Journal of the European Mathematical Society
Pencemaran Nama Baik Dalam Sosial Media
Creators: name: Dinda Zahara Daulay
Publisher: name: Zenodo
Year: 2024

description: Pencemaran nama baik tidak hanya berupa bentuk menyebutkan nama dengan tidak baik melainkan pencemaran nama baik bisa dilakukan dengan membuat nama tersebut dalam posisi yang tidak seharusnya.
Functional differentiability in time-dependent quantum mechanics
Creators: name: Penz, Markus
name: Ruggenthaler, Michael
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: Functional Analysis (math.FA)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: In this work we investigate the functional differentiability of the time-dependent many-body wave function and of derived quantities with respect to time-dependent potentials. For properly chosen Banach spaces of potentials and wave functions Fréchet differentiability is proven. From this follows an estimate for the difference of two solutions to the time-dependent Schrödinger equation that evolve under the influence of different potentials. Such results can be applied directly to the one-particle density and to bounded operators, and present a rigorous formulation of non-equilibrium linear-response theory where the usual Lehmann representation of the linear-response kernel is not valid. Further, the Fréchet differentiability of the wave function provides a new route towards proving basic properties of time-dependent density-functional theory.
USING COMMUNICATIVE GAMES IN TEACHING ENGLISH
Creators: name: Umarova, Zulfizar
Publisher: name: Zenodo
Year: 2024

description: Communicative games have become a successful technique in teaching English language in order to increase learner effectiveness and engagement in the lessons. These interactive and entertaining games provide a dynamic way to practise language skills. In this article, we discuss the advantages of teaching English through communicative games.
A cocycle in the adjoint representation of the orthogonal free quantum groups
Creators: name: Fima, Pierre
name: Vergnioux, Roland
Publisher: name: arXiv
Year: 2014
Subjects: subject: Operator Algebras (math.OA)
subject: FOS: Mathematics

description: We show that the orthogonal free quantum groups are not inner amenable and we construct an explicit proper cocycle weakly contained in the regular representation. This strengthens the result of Vaes and the second author, showing that the associated von Neumann algebras are full II_1-factors and Brannan's result showing that the orthogonal free quantum groups have Haagerup's approximation property. We also deduce Ozawa-Popa's property strong (HH) and give a new proof of Isono's result about strong solidity.
description: 18 pages ; v3 corrects a technical mistake in the proof of Lemma 3.9
Update on Nutation Issues
Creators: name: Ferrandiz, Jose Manuel
name: Escapa, Alberto
Publisher: name: Zenodo
Year: 2022
Subjects: Earth Rotation
Precession
Nutation
Standards
Celestial pole offsets

description: This report addresses how much the IAUU2006 precession and IAU2000 nutation models can be improved in terms of weighted root mean squared, at the short term mainly by using suitable sets of corrections to the linear part of the expressions for the precession of the celestial pole offsets dX, dY, as well as corrections to a certain set of periods of lunisolar and planetary nutations.
description: The authors' work has been supported partially by the Spanish projects PROMETEO/2021/030, funded by the Generalitat Valenciana, and PID2020-119383GB- I00 by Ministerio de Ciencia e Innovación (MCIN/AEI/10.13039/501100011033/)
The Role of URIS and Research Information Management Systems (RIMS) in the Implementation of Open Science
Creators: name: de Castro, Pablo
Publisher: name: Zenodo
Year: 2023

description: The presentation explores the role that Current Research Information Systems (CRIS) -- and specifically the National Ukrainian Research Information System URIS -- play in the implementation of Open Science. CRIS systems help provide an open and comprehensive snapshot of the research that is conducted at an institution or in a whole country and may become key tools in the implementation of specific areas of Open Science such as Open Access and Research Data Management.
Predictability of extreme events in social media
Creators: name: Miotto, José M.
name: Altmann, Eduardo G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: It is part of our daily social-media experience that seemingly ordinary items (videos, news, publications, etc.) unexpectedly gain an enormous amount of attention. Here we investigate how unexpected these events are. We propose a method that, given some information on the items, quantifies the predictability of events, i.e., the potential of identifying in advance the most successful items defined as the upper bound for the quality of any prediction based on the same information. Applying this method to different data, ranging from views in YouTube videos to posts in Usenet discussion groups, we invariantly find that the predictability increases for the most extreme events. This indicates that, despite the inherently stochastic collective dynamics of users, efficient prediction is possible for the most extreme events.
description: 13 pages, 3 figures
title: The bigger the better?: a comparison of institutional repository statistics and sizes across Carnegie R1 institutions
Creators: name: Kraus, Joseph R.
name: Bongiovanni, Emily
Publisher: name: Colorado School of Mines Repository
Year: 2023

description: This project compares the Colorado School of Mines (Mines) Library and Repository with other similarly sized public institutions and with the other R1 universities in Colorado. This poster presents data on institutional repositories at research intensive institutions across the United States, with a specific focus on Mines. There are currently 146 Research 1 (R1) institutions in the Carnegie Classification: 107 public institutions and 39 private institutions. Colorado School of Mines is compared to 27 R1 public universities that have the smallest library budgets (salaries plus materials). This is the 4th quartile of 107 public universities found in the NCES database. Mines is also compared to five R1 institutions in the state of Colorado.
Perturbative $λ$-Supersymmetry and Small $κ$-Phenomenology
Creators: name: Zheng, Sibo
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: For the minimal $λ$-supersymmetry, it stays perturbative to the GUT scale for $λ\leq 0.7$. This upper bound is relaxed when one either takes the criteria that all couplings close to $\sim 4π$ for non-perturbation or allows new fields at the intermediate scale between the weak and GUT scale. We show that a hidden $U(1)_X$ gauge sector with spontaneously broken scale $\sim10$ TeV improves this bound as $λ\leq1.23$ instead. This may induce significant effects on Higgs physics such as decreasing fine tuning involving the Higgs scalar mass, as well as on the small $κ$-phenomenology.
description: Revtex, 7 pages; v4: new U(1) model proposed, journal version
Matrix-F5 algorithms and tropical Gröbner bases computation
Creators: name: Vaccon, Tristan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Symbolic Computation (cs.SC)
subject: Commutative Algebra (math.AC)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Let $K$ be a field equipped with a valuation. Tropical varieties over $K$ can be defined with a theory of Gröbner bases taking into account the valuation of $K$. Because of the use of the valuation, this theory is promising for stable computations over polynomial rings over a $p$-adic fields.We design a strategy to compute such tropical Gröbner bases by adapting the Matrix-F5 algorithm. Two variants of the Matrix-F5 algorithm, depending on how the Macaulay matrices are built, are available to tropical computation with respective modifications. The former is more numerically stable while the latter is faster.Our study is performed both over any exact field with valuation and some inexact fields like $\mathbb{Q}\_p$ or $\mathbb{F}\_q \llbracket t \rrbracket.$ In the latter case, we track the loss in precision, and show that the numerical stability can compare very favorably to the case of classical Gröbner bases when the valuation is non-trivial. Numerical examples are provided.
Measuring the power spectrum of dark matter substructure using strong gravitational lensing
Creators: name: Hezaveh, Yashar
name: Dalal, Neal
name: Holder, Gilbert
name: Kisner, Theodore
name: Kuhlen, Michael
name: Levasseur, Laurence Perreault
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In recent years, it has become possible to detect individual dark matter subhalos near images of strongly lensed extended background galaxies. Typically, only the most massive subhalos in the strong lensing region may be detected this way. In this work, we show that strong lenses may also be used to constrain the much more numerous population of lower mass subhalos that are too small to be detected individually. In particular, we show that the power spectrum of projected density fluctuations in galaxy halos can be measured using strong gravitational lensing. We develop the mathematical framework of power spectrum estimation, and test our method on mock observations. We use our results to determine the types of observations required to measure the substructure power spectrum with high significance. We predict that deep observations ($\sim10$ hours on a single target) with current facilities can measure this power spectrum at the $3σ$ level, with no apparent degeneracy with unknown clumpiness in the background source structure or fluctuations from detector noise. Upcoming ALMA measurements of strong lenses are capable of placing strong constraints on the abundance of dark matter subhalos and the underlying particle nature of dark matter.
description: 8 pages, 6 figures, submitted to ApJ
title: Tracing the Evolution of Digital Cartography in Cartography Textbooks
Creators: name: Lee, Sangho
Publisher: name: TU Wien
Year: 2022
Subjects: subject: digital cartography
subject: textbook
subject: content analysis
subject: history
subject: GIS
subject: web

description: Computer-based systems are established as a quintessential tool in cartography. While their applications have been thoroughly explored, digital cartography as a discipline can be enriched by more historical research. To achieve this, this research identifies cartography textbooks as a lens through which the evolution of digital cartography can be observed. Two cartography textbooks published in recent decades and composed of multiple editions are selected for the analysis. Content analysis is applied as the main methodology to find trends and patterns from changes in digital cartography along with the progress of editions. The findings are supplemented with author interviews to understand the reasoning behind the changes as well as text mining to view the changes from another perspective. The results suggest that the evolution of digital cartography can be observed in various realms, from printing and map design to virtual environments and digital policies. The strongest current is the emergence and proliferation of computer-based GIS and the web, which have led to a substantial shift in cartography in terms of how geodata and maps are produced and disseminated. Furthermore, the heightened relevance of digital technologies is proportionally reflected in the textbooks, supported by increased occurrences of web resources included in textbooks and the results from word frequency and bigram analysis.
Emergence of orientation selective simple cells simulated in deterministic and stochastic neural networks
Creators: name: Stetter, M.
name: Lang, Elmar
name: Müller, A.
Publisher: name: Universität Regensburg
Year: 1993
Subjects: subject: 570 Biowissenschaften, Biologie
subject: Animals
subject: Cybernetics
subject: Ganglia/physiology
subject: Models, Neurological
subject: Nerve Net/physiology
subject: Orientation/physiology
subject: Stochastic Processes
subject: Synapses/physiology
subject: Visual Cortex/physiology

description: The processing of visual data in area 17 of the mammalian cortex is mainly performed by cells with receptive fields which are tuned to different orientations of input stimuli. The mechanisms underlying the emergence of receptive field properties of orientation selective cells are not well understood up to now. Recently, some models for the prenatal development of the receptive fields of orientation selective simple cells have been proposed, which emerge in neural networks trained by Hebb type unsupervised learning rules. These models, however, use different network architectures and are restricted to the case of identical input neurons. In this work, a biologically motivated neural network model with a general architecture is presented. It is trained with a Hebb type updating rule and with uncorrelated input. The input neurons are identified with retinal ganglion cells and exhibit mature Mexican hat type receptive fields. If the receptive fields of the input neurons have identical properties (deterministic model), a set of parameter domains is found, which characterize different kinds of receptive field maturation behaviour of the network. Results obtained by other authors with similar models are contained in this description as special cases. In addition, the more general and rarely investigated stochastic model, where random variations of the parameters describing the receptive fields of the input neurons occur, is investigated. A high sensitivity of the network against these random variations is obtained. In case of large variations of receptive field parameters of the ganglion cells, a qualitatively new kind of maturation behaviour appears. A significant part of the synaptic connections from ganglion cells to the cortical cell is removed and small simple cell receptive fields with only few lobes emerge. The stochastic model is found to provide a better description of the size, scatter and structure of receptive fields present in biological systems, than the deterministic model.
FLOODPLAIN INUNDATION MODELING AND MAPPING FOR GILGEL ABAY RIVER: NILE BASIN, ETHIOPIA
Creators: name: EYUOEL FRANCO
Publisher: name: Zenodo
Year: 2020

description: Flood is an overflowing of water over land surface when the volume of water raises higher than the banks of the water body. Ethiopia is one of the east African countries that is severely affected by it due to the countries rainfall characteristics in which, more than 80% of its annual precipitation falls in four wet month. The objective of this research was to model the flow characteristics of Gilgel-Abay River and to develop flood map for the area. Integration of HEC-HMS and HEC-RAS with ARC-GIS was used to create a regional model for floodplain determination, modeling analysis representation. HEC-HMS was used for hydrologic model calibration with the use of daily time series data for return periods of 2, 10, 25, 50 and 100 years and the model was compared with different frequency analysis methods. HEC-RAS with HEC-GEORAS interface in coordination with ARC-GIS was used to carry out the two dimensional hydraulic modeling and generation of flood maps. Daily discharge and rainfall data were used for HEC-HMS Calibration and Validation with both results showing good match between measured and simulated precipitation data, with acceptable range of coefficient of determination R2 (between 0.7 and 1, Calibration value being 0.72 and Validation 0.73) and Nash-Sutcliffe (NSE) (between 0.5 and 0.75, Calibration value being 0.51 and Validation 0.54). The result of hydrologic model demonstrated peak discharges of 223.9 m3 /s, 367.5 m3 /s, 438.4 m 3 /s, 440.5 m3 /s and 501.6m3 /s for return periods of 2, 10, 25, 50 and 100 years respectively. According to the flood map generated, flooded area for the return periods 2, 10, 25, 50 and 100 years were 6.2 km2 , 7.3 km2 , 7.8 km2 , 7.9km2 and 8.3 km2 respectively. Flood damage of the area was assessed using depth damage function method and the estimated damage to the agricultural land use with water depth greater than 1m was 32.18 km2 . Therefore, non-structural measures like afforestation as well as structural flood protection measures like dikes and levees were recommended to be constructed around the agricultural area.
Temperature and pressure dependence of the nuclear magnetic relaxation rates of -NH2 group in thioacetamide/acetone solutions
Creators: name: Kim, Keon
name: Choi, Young Sang
name: Yoon, Chang Ju
name: Lang, Elmar
Publisher: name: Universität Regensburg
Year: 1992
Subjects: subject: 570 Biowissenschaften, Biologie

description: Information about 14N relaxation rates is obtained for thioacetamide (TA) in acetone from a detailed line-shape analysis of the 1H resonance signal of NH2 group. The effect of pressure and of temperature were investigated, and activation energies for molecular reorientation are given. And also 1H relaxation rates of NH2 group of TA as a function of pressure and temperature are obtained. These results are discussed with the results for the 14N relaxation of amine group.
Goldman systems and bending systems
Creators: name: Nohara, Yuichi
name: Ueda, Kazushi
Publisher: name: arXiv
Year: 2014
Subjects: subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics

description: We show that the moduli space of parabolic bundles on the projective line and the polygon space are isomorphic, both as complex manifolds and symplectic manifolds equipped with structures of completely integrable systems, if the stability parameters are small.
description: 37 pages, 2 figures; v3: added a reference
Single-Name Credit Risk, Portfolio Risk, and Credit Rationing
Creators: name: Arnold, Lutz G.
name: Reeder, Johannes
name: Trepl, Stefanie
Publisher: name: Universität Regensburg
Year: 2010
Subjects: subject: asymmetric information, credit rationing
subject: 330 Wirtschaft
subject: D82
subject: E51
subject: G21

description: This paper introduces non-diversifiable risk in the Stiglitz-Weiss adverse selection model, so that an increase in the average riskiness of the borrower pool causes higher portfolio risk. This opens up the possibility of equilibrium credit rationing. Comparative statics analysis shows that an increase in risk aversion turns a two-price equilibrium into a rationing equilibrium. A two-price equilibrium is more inefficient than a rationing equilibrium, and a usury law that rules out the higher of the two interest rates can be welfare-improving. Contrary to the common result, the equilibrium may be characterized by over-investment.
title: Identity and sport in contemporary China: collectivism vs. individualization
Creators: name: Tsang, Ling Tung
Publisher: name: London School of Economics and Political Science (LSE)
Year: 2023

description: China’s economy and its sporting industry have grown substantially following the success of its open-door economic reform and the ensuing globalization and transnational flow of cultures since the early 2000s. Further coupled with their many recent achievements in international competitions, Chinese athletes are increasingly being recognized in the global sporting arena. Yet, the subject of Chinese sportspeople’s identities is still under theorized in the literature, in which only Western epistemological understandings—especially the long-held stereotypical views stemming from the axis of the “Eastern collectivists vs. Western individualists” binary—are utilized to frame the common discourses in describing Chinese athletes. To address such a stereotype and fill this research gap, this thesis examines how Chinese sportsmen, through their direct reflections of embodied behaviours and actions revealed in their daily lived domains, understand their identities and the related processes of their identification in line with discourses associated with the traditional cultural ideal of Confucianism and contemporary cultural notions of post-structuralism and late-modernism. Drawing on semi-structured interviews (n=40) that were conducted with male Chinese badminton players from provincial professional and university teams in North, Central and South China, along with observations of their team training sessions, this study seeks to elucidate how the athletes identify with collectivism and individualization in their day-to-day circumstances of their everyday lives and also in the context of race and masculinity, which are so significantly interlinked with sports. Contrary to studies which position Chinese individuals’ identities as predominantly collective in nature, I put forward the argument that Chinese sportsmen—and perhaps even applicable to Chinese people in China in general—are also individualists; they possess and perform their dual forms of identities, which operate along the binary axis of collectivism and individualization, in their daily lives.
On new physics in $ΔΓ_d$
Creators: name: Bobeth, Christoph
name: Haisch, Ulrich
name: Lenz, Alexander
name: Pecjak, Ben
name: Tetlalmatzi-Xolocotzi, Gilberto
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Motivated by the recent measurement of the dimuon asymmetry by the DØ collaboration, which could be interpreted as an enhanced decay rate difference in the neutral $B_d$-meson system, we investigate the possible size of new-physics contributions to $ΔΓ_d$. In particular, we perform model-independent studies of non-standard effects associated to the dimension-six current-current operators $(\bar{d} p)(\bar p^{\hspace{0.25mm}\prime} b)$ with $p,p^\prime= u,c$ as well as $(\bar{d}b) (\barττ)$. In both cases we find that for certain flavour or Lorentz structures of the operators sizable deviations of $ΔΓ_d$ away from the Standard Model expectation cannot be excluded in a model-independent fashion.
description: 35 pages, 14 figures. Equation (5.10) corrected, references added. Conclusions remain unchanged
EVALUATION OF THE GUIDELINE FOR INTEGRATED MANAGEMENT OF ADULT AND ADOLESCENT ILLNESS ON HIV PATIENTS IN ADDIS ABABA
Creators: name: Woldie, Martha
Publisher: name: Zenodo
Year: 2007

description: Back ground:-Acute Care module is one of Integrated Management of Adult and

Adolescent illnesses( IMAI) modules relevant for HIV care which are interim guidelines

released for country adaptation and use to help with the emergency scale-up of antiretroviral

therapy (ART) in resource-limited settings.

The module covers disease classifications and treatments for the care of acute illness such as

pneumonia, diarrhea, fever and sexually transmitted infections in adolescents and adults.

Ethiopia is one of the first countries to adapt and apply the guide lines, however, no study to

assess the validity of the guide line in identifying the problem of patients and in leading to

appropriate management decision is performed
Particle Dynamics within the Habitable Zone of Extra Solar Planets
Creators: name: Hinse, Tobias Cornelius
Publisher: name: Zenodo
Year: 2005

description: The orbital stability properties of terrestrial planets within the habitable zone of the star HD4208 (Vogt et al. 2001) is investigated. The habitable zone is determined from Kasting et al. (1993) and provides constrains on Kepler parameters within the (a,e)-space. Independent numerical simulations, using symplectic and interpolation methods (Chambers et al. 2001), are used to study dynamical characteristics (chaotic and confinement within the system's orbital parameter phase space. The MEGNO indicator (Gozdziewski et al. 2001) is used to measure the chaotic nature of the time evolution of Keplerian orbital parameters. Stability properties are inferred by directly considering the dynamics of 2 x 10^3 test particles distributed throughout the habitable zone. The presence of several mean motion resonances are capable in eccentricity excitation up to e = 0.8 for the test particles within the habitable zone. This kind of theoretical dynamical analysis will help future space-based search missions for habitable planets, by providing a mission targeting list of observed extrasolar systems with a high confidence in harbouring terrestrial like planets on dynamically stable orbits confined within the habitable zone.
Characterizing Molecular Modulators at the Intersection of Metabolism and Immunity
Creators: name: Filip, Roxana
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2022
Subjects: Metabolism
Immunity
Host-Pathogen Interactions
Chemical Biology

description: Cellular metabolic and immune pathways can be acted upon by diverse molecular factors. Some examples include small molecules, regulatory proteins or RNAs, intermediary metabolites and hormones. These factors can also be introduced or induced by pathogens during infections. Indeed, it is known that complex interplay exists between metabolism and immunity. However, the ways in which these interactions occur, and the nature of the players are active subjects of research. Herein, three different studies are presented which investigate the roles of three distinct modulators of metabolism and/or immunity. Firstly, a natural product produced by a pathogenic fungus is shown to activate the aryl hydrocarbon receptor and induce the expression of xenobiotic metabolizing enzymes. Secondly, the modulation of lipid metabolism by an immunometabolic antiviral microRNA, microRNA-185, is deconvoluted using activity-based protein profiling (ABPP), transcriptomic and lipidomic analysis. This study also identifies a novel enzymatic target of microRNA-185 which can be targeted pharmacologically to reduce hepatitis C virus infectivity. Finally, a third study investigates the link between a poorly characterized enzyme, lysophospholipase-like 1 (LYPLAL1), and hepatic glucose metabolism using a specific activity-based probe. Overall, the work presented in this thesis makes use of various molecular and chemical biology methods to probe pathways which are acted upon by structurally diverse factors to improve our understanding of host-pathogen interactions and metabolism.
REDES SOCIAIS AO LONGO DA ESTRADA DE FERRO CARAJÁS NA AMAZÔNIA ORIENTAL
Creators: name: Filipe Dos Santos, Jorge
name: Maia, Maria Bernadete
name: Maneschy, Maria Cristina
name: Matlaba, Valente
name: Aroudo Mota, José
Publisher: name: Finisterra
Year: 2019

description: A Estrada de Ferro Carajás (EFC), de 900km, escoa os minérios do sudeste do Pará ao porto de São Luís, no Maranhão. As comunidades lindeiras têm maus indicadores sociais e carências de políticas públicas. Para conhecer a rede institucional desse território, foi entrevistada uma amostra de 17 líderes de associações comunitárias e instituições parceiras. A rede mostrou-se esparsa, com poucos elos de alta centralidade e reduzidos fluxos de fontes externas até as comunidades locais, limitando sua capacidade de articulação coletiva e de desenvolvimento. Daí, possivelmente, a eclosão de conflitos como forma de expressão. O fortalecimento de uma rede densa e diversa por parte de stakeholders locais poderá transformar o caráter de “redes de resistência” contra impactos adversos, para “redes de colaboração” no desenvolvimento sustentável.
description: Finisterra, vol. 53 n.º 109 (2018)
A bound on the charm chromo-EDM and its implications
Creators: name: Sala, Filippo
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We derive bounds on the electric and chromo-electric dipole moments of the charm quark. The second one turns out to be particularly strong, and we quantify its impact on models that allow for a sizeable flavour violation in the up quark sector, like flavour alignment and Generic U(2)^3. In particular we show how the bounds coming from the charm and up CEDMs constrain the size of new physics contributions to direct flavour violation in D decays. We also specialize our analysis to the cases of Supersymmetry with split families and composite Higgs models. The results exposed in this paper motivate both an increase in experimental sensitivity to fundamental hadronic dipoles, and a further exploration of the SM contribution to flavour violating D decays.
description: 16 pages, 1 figure. v2: comments and references added, published in JHEP. v3: oversights fixed in two equations, all the rest unchanged
Programm der 3. SaxFDM-Tagung
Creators: name: Hundt, Carolin
Publisher: name: Zenodo
Year: 2022
Subjects: SaxFDM
Konferenz
SaxFDM-Tagung

description: Das Programm der 3. SaxFDM-Tagung in der Leipziger Albertina zum nachlesen. Die Beiträge der einzelnen Teilnehmenden sind auf dem SaxFDM-Zenodo-Kanal zu finden.
title: Vom Topos des Scheiterns als konstituierender Kraft: Ein Essay über Erkenntnisprozesse in den Digital Humanities
Creators: name: Gengnagel, Tessa
Publisher: name: Zeitschrift für digitale Geisteswissenschaften - ZfdG
Year: 2022

description: Fabrikation von Erkenntnis – Experimente in den Digital Humanities. Hg. von Manuel Burghardt, Lisa Dieckmann, Timo Steyer, Peer Trilcke, Niels Walkowski, Joëlle Weis, Ulrike Wuttke. Wolfenbüttel 2021—2022. (= Zeitschrift für digitale Geisteswissenschaften / Sonderbände, 5)
description: Das Experimentieren weckt in den Diskursen der Digital Humanities oftmals Assoziationen von Versuch und Spiel. Eine darüber hinaus wichtige Komponente dieses rhetorischen Stilmittels wird in deutschsprachigen Publikationen allerdings weithin übersehen: und zwar seine Verbindung zu einer »importance of failure«. Der Beitrag hat primär zum Ziel, diesen Topos des Scheiterns vor dem Hintergrund erkenntnistheoretischer Überlegungen zu besprechen, die in dem Forschungsfeld gängig sind und sich um die Möglichkeiten der Digital Humanities drehen. Abschließend wird der Blick auf den Deutungsrahmen gelenkt, innerhalb dessen Infrastrukturen als ›Laboratorien‹ und Methoden als ›Experimente‹ verstanden werden; eine Einordnung, hinter der sich die Notwendigkeit für eine Wertbestimmung verbirgt.
THE AESTHETICS OF RUINS: FAILURE, DECAY, PLANNING AND POVERTY
Creators: name: Sarmento, João
Publisher: name: Finisterra
Year: 2019

description: Ruins take many shapes and result from numerous and diverse human and non-human interactions. Acknowledging their place and arrangements, considering their spatial orderings, evaluating hierarchies, patterns and significations, and unravelling their ‘performance’, role, effect and marked absences, is key to a critical and significant engagement with the politics, grammars and productive power of materials that are in place. Ruins are material sites that animate new possibilities of living: they should be perceived as dynamic and relational, as interstitial, as sites of plurality, plasticity, dismantling and destabilizing the power of endless self-invention. Schönle’s (2006: 652) argument that ‘we cannot leave ruins alone and let them simply exist in their mute materiality’ guides the following four examples. While ruins pose challenges to planners and to politicians, constituting threats and opportunities, they speak to us of decadence, failure, loss, beauty, change and pleasure.
description: Finisterra, vol. 53 n.º 109 (2018)
Hypercontractivity of quasi-free quantum semigroups
Creators: name: Temme, Kristan
name: Pastawski, Fernando
name: Kastoryano, Michael J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Hypercontractivity of a quantum dynamical semigroup has strong implications for its convergence behavior and entropy decay rate. A logarithmic Sobolev inequality and the corresponding logarithmic Sobolev constant can be inferred from the semigroup's hypercontractive norm bound. We consider completely-positive quantum mechanical semigroups described by a Lindblad master equation. To prove the norm bound, we follow an approach which has its roots in the study of classical rate equations. We use interpolation theorems for non-commutative $L_p$ spaces to obtain a general hypercontractive inequality from a particular $p \rightarrow q$-norm bound. Then, we derive a bound on the $2 \rightarrow 4$-norm from an analysis of the block diagonal structure of the semigroup's spectrum. We show that the dynamics of an $N$-qubit graph state Hamiltonian weakly coupled to a thermal environment is hypercontractive. As a consequence this allows for the efficient preparation of graph states in time ${\rm poly}(\log(N))$ by coupling at sufficiently low temperature. Furthermore, we extend our results to gapped Liouvillians arising from a weak linear coupling of a free-fermion systems.
title: Experiments in the digital laboratory
Creators: name: Lang, Sarah
Publisher: name: Melusina Press
Year: 2022

description: Fabrikation von Erkenntnis: Experimente in den Digital Humanities -
description: The notion of experiment is widely discussed in Digital Humanities, yet a precise terminology is still lacking. This article argues that a narrow set of scenarios in the subfield of the Computational Humanities can implement a definition close to that of the Sciences which transcends the metaphor of playful exploration. It proposes that we should look to those Humanities disciplines which have already integrated experimental methods into their hermeneutic arsenal such as Experimental Archaeology and the Experimental History of Science. These share an emphasis on distinguishing ›experiencing‹ from ›experimenting‹ which I argue should be applied to the Digital Humanities notion of experiment as well.
description: Der Experimentbegriff hat in den Digital Humanities Konjunktur, doch mangelt es bisher an terminologischer Präzision. Dieser Beitrag argumentiert, dass in einer kleineren Menge an Szenarien in den Computational Humanities ein strengerer ›naturwissenschaftlicher‹ Experimentbegriff verwendet werden könnte, der über die Metaphorik des spielerischen Explorierens hinausgeht. Dabei schlägt er vor, sich bei dieser Einordnung vor allem an jenen geisteswissenschaftlichen Disziplinen zu orientieren, die experimentelle Methoden bereits in ihre Hermeneutiken integriert haben, wie etwa die Experimentelle Archäologie oder die Experimentelle Wissenschaftsgeschichte, die hierbei zwischen ›experiencing‹ und ›experimenting‹ unterscheiden.
Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation
Creators: name: Bucsai, Martina Aguiar
name: Idel, Christian
name: Wollenberg, Barbara
name: Mannhalter, Christine
name: Verschoor, Admar
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry. To do so, we used washed platelets from healthy human donors. We combined aggregometry, an assay of platelet functionality, with flow cytometry and ELISA to detect and correlate, respectively, platelet aggregation, activation, and granule release. While tirofiban effectively inhibited agonist-induced platelet aggregation (thrombin receptor-activating peptide 6 (TRAP), convulxin (CVX), U46619 and IV.3), the surface expression of P-selectin and CD63 and granule release of RANTES were significantly increased, indicating that tirofiban enhances degranulation, uncoupled from aggregation. The results show that tirofiban alters the activation phenotype of platelets, something that should be considered when using tirofiban to enable flow cytometric analysis of activated but unaggregated platelet suspensions.
HOUSING VACANCY IN ATLANTIC EUROPE: ORIGINS AND EFFECTS ON SMALL TOWNS IN GALICIA
Creators: name: Brouard-Sala, Quentin
name: Lois-Gonzales, Rubén
name: Madeline, Philippe
name: Marie, Maxime
Publisher: name: Finisterra
Year: 2019

description: Since 1950, the countryside of Western Europe has been affected by profound socio-spatial changes. Due to net migration and the nuclearisation of families, the urbanisation process has led to demographic growth in rural areas relatively close to big cities. This has led to an increase in mobility and the development of a lifestyle that centres around the suburban model, which has contributed to older buildings being disparaged. After three decades of policies to aid the construction of new buildings, numerous vacant older housings can be found in Western Europe. At a time when the suburban model is being called into question by politicians, vacant housing is at the heart of the demographic, economic and political issues of rural areas.


A housing is said to be vacant when it is unoccupied and proposed to sale, hire, waiting to be occupied or that is kept vacant by its owner. The Spanish countryside, especially Galicia, has numerous vacant houses. In the small towns of Galicia, the area studied, vacancy is generally over 20%, broadly higher than the “normal” rate (for property speculation) of between 6% and 8%. This vacancy rate includes both older, abandoned housings and new construction.
description: Finisterra, vol. 53 n.º 109 (2018)
Platelet inhibition by low-dose aspirin is not influenced by body mass or weight
Creators: name: Heffron, Sean P.
name: Windheim, Joseph
name: Barrett, Tessa J.
name: Voora, Deepak
name: Berger, Jeffrey S.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Cardiology

description: Aspirin’s clinical efficacy may be influenced by body weight and mass. Although inadequate platelet inhibition by aspirin is suggested as responsible, evidence for this in non-diabetic patients is sparse. We investigated the influence of body weight and mass on aspirin’s inhibition of platelet aggregation in healthy adults without diabetes. Cohort one (NYU, n = 84) had light transmission aggregometry (LTA) of platelet-rich plasma to submaximal adenosine diphosphate (ADP) and arachidonic acid (AA) before and following 1 week of daily 81 mg non-enteric coated aspirin. Subjects in the validation cohort (Duke, n = 66) were randomized to 81 mg or 325 mg non-enteric coated aspirin for 4 weeks, immediately followed by 4 weeks of the other dose, with LTA to submaximal collagen, ADP, and AA before and after each dosage period. Body mass index (BMI) range was 18.0–57.5 kg/m2 and 25% were obese. Inhibition of platelet aggregation was similar irrespective of BMI, body weight and aspirin dose. There was no correlation between platelet aggregation before or after aspirin with BMI or body weight. Our data demonstrate that aspirin produces potent inhibition of direct and indirect COX1-mediated platelet aggregation in healthy adults without diabetes regardless of body weight or mass – suggesting that other mechanisms explain lower preventive efficacy of low-dose aspirin with increasing body weight/mass.
THE IMPACT OF SOCIO-ECONOMIC FACTORS ON THE HEALTH OF THE MOROCCAN IMMIGRANTS IN NAVARRA (SPAIN)
Creators: name: Montoro-Gurich, Carolina
Publisher: name: Finisterra
Year: 2019

description: This paper explores the relationship between immigration and health status variation among Moroccan immigrants from a gender perspective, using data from a cross-sectional ethnographic survey conducted in the Spanish region of Navarre. Results show, against the literature, that women have a better health status variation than men, probably because men have a higher age profile and a longer stay in Spain. The binary logistic regression reveals important differences in social determinants by gender. Paid employment is the most positive, significant factor for health among women. Close social ties with compatriots, living in an inexpensive old house and, to a lesser extent, having a secondary level of educational achievement are the key factors for men. The economic implications of daily life have an impact on the health of Moroccan immigrants of both sexes.
description: Finisterra, vol. 53 n.º 109 (2018)
MULTIPLICIDAD DE CAMBIOS DE USOS DEL SUELO. ESTUDIO DE CASO EN LA COMUNIDAD DE MADRID
Creators: name: Gallardo, Marta
Publisher: name: Finisterra
Year: 2019

description: En las décadas previas a la crisis económica global de 2007, España y, en particular la Comunidad Autónoma de Madrid, por su condición de capitalidad, registraron altas tasas de cambios de usos del suelo, relacionadas con un crecimiento de los usos urbanos, comerciales y de transporte. Entre 1990 y 2006, dicha región registró un incremento en usos artificiales de casi un 70%. Estos cambios se han localizado por todo su territorio afectando incluso a espacios naturales protegidos. Mediante la superposición de cuatro datos temporales correspondientes a los años 1982, 1990, 2000 y 2006, se obtienen estadísticas y resultados espacio-temporales, constatando que la dinámica de cambio de los usos del suelo en la Comunidad de Madrid se ha sucedido de manera rápida e intensa, registrándose en dicho periodo temporal hasta tres transiciones de usos del suelo en ciertas áreas de la región, especialmente alrededor de su área metropolitana. Dichos cambios están asociados a la mejora de la accesibilidad con la construcción de nuevas carreteras radiales. La artificialización y el sellado del suelo, y el crecimiento urbano de forma dispersa, suponen un deterioro ecológico importante, ligado a perturbaciones, pérdidas de biodiversidad o una fragmentación del paisaje.
description: Finisterra, vol. 53 n.º 109 (2018)
Nonlinear Maximal Monotone Extensions of Symmetric Operators
Creators: name: Posilicano, Andrea
Publisher: name: arXiv
Year: 2014
Subjects: subject: Functional Analysis (math.FA)
subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: Given a linear semi-bounded symmetric operator $S\ge -ω$, we explicitly define, and provide their nonlinear resolvents, nonlinear maximal monotone operators $A_Θ$ of type $λ>ω$ (i.e. generators of one-parameter continuous nonlinear semi-groups of contractions of type $λ$) which coincide with the Friedrichs extension of $S$ on a convex set containing ${\mathscr D}(S)$. The extension parameter $Θ\subset{\mathfrak h}\times{\mathfrak h}$ ranges over the set of nonlinear maximal monotone relations on an auxiliary Hilbert space $\mathfrak h$ isomorphic to the deficiency subspace of $S$. Moreover $A_Θ+λ$ is a sub-potential operator (i.e. is the sub-differential of a lower semicontinuos convex function) whenever $Θ$ is sub-potential. Examples describing Laplacians with nonlinear singular perturbations supported on null sets and Laplacians with nonlinear boundary conditions on a bounded set are given.
description: Revised final version. To appear in Journal of Evolution Equations