cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Δοκιμές αξιολόγησης συστημάτων ML: Διαδικασίες, Μέθοδοι & Μετρικές
Creators: name: Σουρλάς, Βασίλειος
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2024
Subjects: subject: δοκιμές αξιολόγησης
subject: μηχανική μάθηση
subject: τεχνητή νοημοσύνη
subject: βαθεία μάθηση
subject: μοντέλα
subject: νευρωνικά δίκτυα
subject: ακρίβεια
subject: πληρότητα
subject: κάλυψη

description: Μ.Δ.Ε. 64
description: Η δοκιμή αξιολόγησης των συστημάτων ML είναι μια απαιτητική και δαπανηρή διαδικασία καθώς τα συστήματα αυτά παρουσιάζουν υψηλή πολυπλοκότητα, χρειάζονται μεγάλο όγκο δεδομένων για να πραγματοποιήσουν καλές προβλέψεις, και χρησιμοποιούν πολύπλοκους, πιθανολογικούς μη ντετερμινιστικούς αλγόριθμους. Η παρούσα διπλωματική εργασία επιδιώκει να δώσει μια ολοκληρωμένη εικόνα των σύγχρονων μεθοδολογιών που χρησιμοποιούνται για τις δοκιμές αξιολόγησης των συστημάτων ML, συμβάλλοντας στη βελτίωση της αξιοπιστίας και της απόδοσης τους. Αρχικά, αναλύεται η διαδικασία ανάπτυξης ενός συστήματος ML, από τη συλλογή και την προεπεξεργασία των δεδομένων, έως και την παρακολούθηση της συμπεριφοράς και τρόπου λειτουργίας του συστήματος σε παραγωγικό περιβάλλον. Στη συνέχεια, αναλύεται η διαδικασία αξιολόγησης των συστημάτων AI, ενώ επίσης επισημαίνονται οι βασικές διαφορές των δοκιμών αξιολόγησης τους σε σύγκριση με τα συμβατικά συστήματα. Ιδιαίτερη έμφαση δίνεται στις μετρικές αξιολόγησης που χρησιμοποιούνται για την μέτρηση της απόδοσης των μοντέλων ML και περιγράφονται τα μειονεκτήματα και τα πλεονεκτήματα τους. Ακόμα, παρουσιάζονται οι μεθοδολογίες δοκιμών, όπως οι Differential, Metamorphic, Mutation και Combinatorial, οι οποίες βοηθούν τόσο στη δημιουργία δοκιμαστικών περιπτώσεων όσο και στην αντιμετώπιση του προβλήματος του test oracle. Τέλος, συζητούνται η επάρκεια των δοκιμών και οι τεχνικές ιεράρχησης και μείωσης των δοκιμαστικών περιπτώσεων για την αποδοτικότερη και αποτελεσματικότερη αξιολόγηση των ML συστημάτων
A Perturbation of the Dunkl Harmonic Oscillator on the Line
Creators: name: López, Jesús A. Álvarez
name: Calaza, Manuel
name: Franco, Carlos
Publisher: name: arXiv
Year: 2014
Subjects: subject: Spectral Theory (math.SP)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: Let $J_σ$ be the Dunkl harmonic oscillator on ${\mathbb{R}}$ ($σ>-\frac{1}{2}$). For $00$, it is proved that, if $σ>u-\frac{1}{2}$, then the operator $U=J_σ+ξ|x|^{-2u}$, with appropriate domain, is essentially self-adjoint in $L^2({\mathbb{R}},|x|^{2σ} dx)$, the Schwartz space ${\mathcal{S}}$ is a core of $\overline U^{1/2}$, and $\overline U$ has a discrete spectrum, which is estimated in terms of the spectrum of $\overline{J_σ}$. A generalization $J_{σ,τ}$ of $J_σ$ is also considered by taking dif\/ferent parameters $σ$ and $τ$ on even and odd functions. Then extensions of the above result are proved for $J_{σ,τ}$, where the perturbation has an additional term involving, either the factor $x^{-1}$ on odd functions, or the factor $x$ on even functions. Versions of these results on ${\mathbb{R}}_+$ are derived.
description: We correct the second main theorem of the previous version, by the first two authors. The corrections concern mainly certain estimates, which were also improved by adding more methods
Overspinning a Kerr black hole: the effect of self-force
Creators: name: Colleoni, Marta
name: Barack, Leor
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study the scenario in which a massive particle is thrown into a rapidly rotating Kerr black hole in an attempt to spin it up beyond its extremal limit, challenging weak cosmic censorship. We work in black-hole perturbation theory, and focus on non-spinning, uncharged particles sent in on equatorial orbits. We first identify the complete parameter-space region in which overspinning occurs when back-reaction effects from the particle's self-gravity are ignored. We find, in particular, that overspinning can be achieved only with particles sent in from infinity. Gravitational self-force effects may prevent overspinning by radiating away a sufficient amount of the particle's angular momentum ("dissipative effect"), and/or by increasing the effective centrifugal repulsion, so that particles with suitable parameters never get captured ("conservative effect"). We analyze the full effect of the self-force, thereby completing previous studies by Jacobson and Sotiriou (who neglected the self-force) and by Barausse, Cardoso and Khanna (who considered the dissipative effect on a subset of orbits). Our main result is an inequality, involving certain self-force quantities, which describes a necessary and sufficient condition for the overspinning scenario to be overruled. This "censorship" condition is formulated on a certain one-parameter family of geodesics in an extremal Kerr geometry. We find that the censorship condition is insensitive to the dissipative effect (within the first-order self-force approximation used here), except for a subset of perfectly fine-tuned orbits, for which a separate censorship condition is derived. We do not obtain here the self-force input needed to evaluate either of our two conditions, but discuss the prospects for producing the necessary data using state-of-the-art numerical codes.
description: 25 pages, 4 figures
title: Language-independent pre-processing of large document bases for text classification
Creators: name: Justin. Wang, Yanbo
Publisher: name: University of Liverpool Repository
Year: 2023

description: Text classification is a well-known topic in the research of knowledge discovery in databases. Algorithms for text classification generally involve two stages. The first is concerned with identification of textual features (i.e. words andlor phrases) that may be relevant to the classification process. The second is concerned with classification rule mining and categorisation of "unseen" textual data. The first stage is the subject of this thesis and often involves an analysis of text that is both language-specific (and possibly domain-specific), and that may also be computationally costly especially when dealing with large datasets. Existing approaches to this stage are not, therefore, generally applicable to all languages. In this thesis, we examine a number of alternative keyword selection methods and phrase generation strategies, coupled with two potential significant word list construction mechanisms and two final significant word selection mechanisms, to identify such words andlor phrases in a given textual dataset that are expected to serve to distinguish between classes, by simple, language-independent statistical properties. We present experimental results, using common (large) textual datasets presented in two distinct languages, to show that the proposed approaches can produce good performance with respect to both classification accuracy and processing efficiency. In other words, the study presented in this thesis demonstrates the possibility of efficiently solving the traditional text classification problem in a language-independent (also domain-independent) manner.
Parton distributions need representative sampling
Creators: name: Courtoy, Aurore
name: Huston, Joey
name: Nadolsky, Pavel
name: Xie, Keping
name: Yan, Mengshi
name: Yuan, C. -P.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In global QCD fits of parton distribution functions (PDFs), a large part of the estimated uncertainty on the PDFs originates from the choices of parametric functional forms and fitting methodology. We argue that these types of uncertainties can be underestimated with common PDF ensembles in high-stake measurements at the Large Hadron Collider and Tevatron. A fruitful approach to quantify these uncertainties is to view them as arising from sampling of allowed PDF solutions in a multidimensional parametric space. This approach applies powerful insights gained in recent statistical studies of large-scale population surveys and quasi-Monte Carlo integration methods. In particular, PDF fits may be affected by the big data paradox, which stipulates that more experimental data do not automatically raise the accuracy of PDFs -- close attention to the data quality and sampling of possible PDF solutions is as essential. To test if the sampling of the PDF uncertainty of an experimental observable is truly representative of all acceptable solutions, we introduce a technique (``a hopscotch scan'') based on a combination of parameter scans and stochastic sampling. With this technique, we show that the PDF uncertainty on key LHC cross sections at 13 TeV obtained with the public NNPDF4.0 fitting code is larger than the nominal uncertainty obtained with the published NNPDF4.0 Monte-Carlo replica sets, when accounting for the likelihood distribution. On the same grounds, the uncertainties on the charm distribution at a large momentum fraction $x$ and gluon PDF at small $x$ are enlarged. In PDF ensembles obtained in the analytic minimization (Hessian) formalism, the tolerance on the PDF uncertainty must be based on sufficiently complete sampling of PDF functional forms and choices of the experiments.
description: 26 pages, 10 figures; this version includes expanded discussion added in the journal version and detailed comparisons supplementary to the journal version
Possible association between a genetic polymorphism at 8q24 and risk of upper gastrointestinal cancer
Creators: name: El-Omar, Emad M.
name: Lochhead, Paul
name: Risch, Harvey A.
name: Vaughan, Thomas L.
name: Hold, Georgina L.
name: Lissowska, Jolanta
name: Chow, Wong-Ho
name: Gammon, Marilie D.
name: Mukhopadhya, Indrani
name: Rabkin, Charles S.
name: Ng, Michael T.H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Over recent years, genome wide association studies (GWAS) have contributed to our understanding of genetic susceptibility to sporadic cancer. In this study, we assessed the association between upper gastrointestinal cancer risk and four GWAS-identified single nucleotide polymorphisms (SNPs), previously implicated in prostate and colorectal cancer susceptibility. Genotyping for each SNP was performed in two, independent, Caucasian, population-based case-control studies. The first study comprised 290 gastric cancer cases and 374 controls. The second study included 185 non-cardia gastric cancers, 123 cardia cancers, 158 oesophageal cancers, and 209 controls. Odds ratios were computed from logistic models and adjusted for potential confounding variables. An inverse association was observed between the SNP rs1447295, located at 8q24, and gastric cancer risk in the first study population (odds ratio [OR] = 0.63; 95% Confidence Interval [CI], 0.41–0.97). A positive association was observed for the same SNP and oesophageal squamous cell carcinoma in the second study population (OR = 7.43; 95% CI, 1.37–49.98). No significant associations were detected in either study for the three remaining SNPs (rs6983297, rs10505477 and rs719725). Our data represent novel findings on heritable susceptibility to gastric and oesophageal cancer and warrant validation in additional populations.
1.60 m Telescope P-E
Creators: name: Oliveira, V. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: A comparative the telescope twin P-E, one is in Observatório Pico dos Dias, Brazil, other in Observatoire Mont-Mégantic, Québec, Canada. The same project, the same beginning configuration but different stories, different solutions for the problems by the years.
description: 4 pages, text in Portuguese
Influence of prediagnostic recreational physical activity on survival from breast cancer
Creators: name: Gammon, Marilie D.
name: Bradshaw, Patrick T.
name: Teitelbaum, Susan L.
name: Eng, Sybil M.
name: Cleveland, Rebecca J.
name: Neugut, Alfred I.
name: Stevens, June
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Recreational physical activity (RPA) is associated with a reduced risk of developing breast cancer, but there is limited research on whether prediagnostic RPA influences survival after breast cancer diagnosis.
High School Students' Understandings and Representations of the Electric Field
Creators: name: Cao, Ying
name: Brizuela, Bárbara M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: This study investigates the representations and understandings of electric fields expressed by Chinese high school students 15 to 16 years old who have not received high school level physics instruction. The physics education research literature has reported students conceptions of electric fields post-instruction as indicated by students performance on textbook-style questions. It has, however, inadequately captured student ideas expressed in other situations yet informative to educational research. In this study, we explore students ideas of electric fields pre-instruction as shown by students representations produced in open-ended activities. 92 participant students completed a worksheet that involved drawing comic strips about electric charges as characters of a cartoon series. Three students who had spontaneously produced arrow diagrams were interviewed individually after class. We identified nine ideas related to electric fields that these three students spontaneously leveraged in the comic strip activity. In this paper, we describe in detail each idea and its situated context. As most research in the literature has understood students as having relatively fixed conceptions and mostly identified divergences in those conceptions from canonical targets, this study shows students reasoning to be more variable in particular moments, and that variability includes common sense resources that can be productive for learning about electric fields.
description: 19 pages
Celecoxib pre-treatment in human colorectal adenocarcinoma patients is associated with gene expression alterations suggestive of diminished cellular proliferation
Creators: name: Watson, Mark A.
name: Church, Robert
name: Mcleod, Howard L.
name: Lee, Soo-Youn
name: Fleshman, James W.
name: Auman, James Todd
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Cancer cells treated with the cyclooxygenase-2 inhibitor celecoxib show growth inhibition and induced apoptosis. This study was conducted to determine if the same processes are relevant to celecoxib’s effects on human colorectal adenocarcinomas treated in vivo. A cohort of 23 patients with primary colorectal adenocarcinomas was randomized to receive a 7-day course of celecoxib (400 mg b.i.d.) or no drug prior to surgical resection. Gene expression profiling was performed on resected adenocarcinomas from the cohort of patients. Using fold change (>1.5) and p-value (<0.05) cut-offs, 190 genes were differentially expressed between adenocarcinomas from patients receiving celecoxib and those that did not. The celecoxib pre-treated samples showed decreased expression levels in multiple genes involved in cellular lipid and glutathione metabolism; changes associated with diminished cellular proliferation. Celecoxib pre-treatment for 7 days in vivo is associated with alterations in colorectal adenocarcinoma gene expression which are suggestive of diminished cellular proliferation.
The open past in an indeterministic physics
Creators: name: Del Santo, Flavio
name: Gisin, Nicolas
Publisher: name: arXiv
Year: 2022
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Discussions on indeterminism in physics focus on the possibility of an open future, i.e. the possibility of having potential alternative future events, the realisation of one of which is not fully determined by the present state of affairs. Yet, can indeterminism affect also the past, making it open as well? We show that by upholding principles of finiteness of information one can entail such a possibility. We provide a toy model that shows how the past could be fundamentally indeterminate, while also explaining the intuitive (and observed) asymmetry between the past -- which can be remembered, at least partially -- and the future -- which is impossible to fully predict.
description: 5 pages, 2 figures, revised version
Σχεδιασμός και Υλοποίηση Συστήματος Καταγραφής, Παρακολούθησης και Διαχείρισης Στίγματος Κινητών Χρηστών σε Εσωτερικό Χώρο
Creators: name: Καλλίνης, Άγγελος
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2021
Subjects: subject: Motion tracking, Motion simulation, Heatmap, Pattern extraction, heatmap.js, jquery, javascript, mysql

description: Μ.Δ.Ε. 61
description: Το θέμα της παρούσας μεταπτυχιακής διατριβής πραγματεύεται τον σχεδιασμό και την υλοποίηση διαδικτυακής (web) εφαρμογής, ικανής να καταγράφει ανθρώπινη κίνηση σε ορισμένο χώρο, να αποθηκεύει και να επεξεργάζεται τα δεδομένα, να την αποτυπώνει στο διδιάστατο επίπεδο και να εξάγει συμπεράσματα. Το παραπάνω σύστημα θεωρητικά βρίσκει μεγάλη ποικιλία εφαρμογών ειδικά σε περιπτώσεις που η παρακολούθηση κίνησης σε έναν περιορισμένο χώρο είναι επιβεβλημένη για λόγους αποδοτικότητας. Παράδειγμα εφαρμογής είναι ένας εκθεσιακός ή μουσειακός χώρος που η παρακολούθηση της κίνησης των επισκεπτών και η εξαγωγή μοτίβων θα βοηθούσε στην καλύτερη κατανόηση της συμπεριφοράς τους και των ενδιαφερόντων τους και στην εκ των πραγμάτων καλύτερη τοποθέτηση των εκθεμάτων. Τα αποτελέσματα για το σκοπό της εργασίας βασίζονται σε τεχνητά δεδομένα.
$L(1,1)-$ Labeling of Direct Product of Cycles
Creators: name: Adefokun, Tayo Charles
name: Ajayi, Deborah Olayide
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C35

description: An $L(1,1)$-labeling of a graph $G$ is an assignment of labels from $\{0,1 \cdots, k \}$ to the vertices of $G$ such that two vertices that are adjacent or have a common neighbor receive distinct labels. The $λ_1^1-$ number, $λ_1^1(G)$ of $G$ is the minimum value $k$ such that $G$ admits an $L(1,1)$ labeling. We establish the $λ_1^1-$ numbers for direct product of cycles $C_m \times C_n$ for all positive $m, n \geq 3$, where both $m,n$ are even or when one of them is even and the other odd.
description: 17 pages, 13 figures
Ευνοϊκά Μέτρα, Μάρτυρες του Στέμματος και Μάρτυρες Δημοσίου Συμφέροντος. Η έννοια του Whistleblowing
Creators: name: Τερλεξή, Μαρία Ιωάννη
Publisher: name: Aristotle University of Thessaloniki
Year: 2023
Subjects: Μάρτυρες του Στέμματος
Μάρτυρες Δημοσίου Συμφέροντος
Οδηγία 2019/1937
Crown Witnesses
Public Interest Witnesses
Directive 2019/1937

description: Η παρούσα μελέτη πραγματεύεται τη σύγκριση των μαρτύρων του στέμματος και των μαρτύρων δημοσίου συμφέροντος, ως εργαλεία αντεγκληματικής πολιτικής. Στο πρώτο κεφάλαιο παρατίθενται οι μάρτυρες του στέμματος, ήτοι πρόσωπα με ποινική ευθύνη, που, αποσκοπώντας στην ευνοϊκή μεταχείριση, συνεργάζονται με τις αρχές. Γίνεται περαιτέρω εμβάθυνση στους καταγγέλλοντες πράξεις διακίνησης ναρκωτικών (άρθρο 27 ν. 4139/2013), τους εμπλεκόμενους στο οργανωμένο έγκλημα (άρθρο 187Γ ΠΚ) και τους αναφέροντες πράξεις διαφθοράς (263Α ΠΚ), ενώ αναδεικνύεται η σύγκρουση των αρχών της νομιμότητας και σκοπιμότητας. Έπειτα σκιαγραφείται η έννοια του Whistleblowing, δηλαδή η αποκάλυψη πληροφοριών για πράξεις διαφθοράς, καθώς και η, κατά το άρθρο 47 ΚΠΔ, έννοια και η νομική και φυσική προστασία των μαρτύρων δημοσίου συμφέροντος, δηλαδή καταγγελλόντων πράξεις διαφθοράς χωρίς ποινική ευθύνη. Ιδιαιτέρως επισημαίνεται η Οδηγία 2019/1937 και ο οικείος νόμος 4990/2022, που κατοχυρώνουν τα ελάχιστα πρότυπα προστασίας των εν λόγω μαρτύρων. Το τελευταίο κεφάλαιο άπτεται της ανάλυσης της νομολογίας του ΕΔΔΑ αφενός ως προς τα κριτήρια για την απόδοση χαρακτηρισμού των Whistleblowers και αφετέρου ως προς την εναρμόνιση των αντικρουόμενων συμφερόντων του μάρτυρα και του κατηγορουμένου.
description: This study deals with the comparison of crown witnesses and public interest witnesses [whistleblowers], as means of anti-crime policy. The first chapter refers to crown witnesses, i.e. persons with criminal responsibility, who, in order to obtain favorable treatment, cooperate with the authorities. Further we delve into those who report drug trafficking (Article 27 of Law 4139/2013), organized crime (Article 187C of the Criminal Code) and acts of corruption (263A of the Criminal Code), while we highlight the conflict between the principles of legality and expediency. Then the concept of whistleblowing is outlined, i.e. the disclosure of information about acts of corruption, as well as, according to Article 47 CPC, the concept and the legal and physical protection of public interest witnesses, i.e. those who report acts of corruption without criminal liability. Directive 2019/1937 and the relevant law 4990/2022, which enshrine the minimum standards of protection of the witnesses in question, are particularly highlighted. The last chapter deals with the analysis of ECHR case law in terms of the criteria for the classification of Whistleblowers on the one hand and on the other hand in terms of harmonizing the conflicting interests of the witness and the accused.
description: Σε συνεργασία με: Πανεπιστήμιο Λευκωσίας (Κύπρος)
You Need to Read Again: Multi-granularity Perception Network for Moment Retrieval in Videos
Creators: name: Sun, Xin
name: Wang, Xuan
name: Gao, Jialin
name: Liu, Qiong
name: Zhou, Xi
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Artificial Intelligence (cs.AI)
subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: Moment retrieval in videos is a challenging task that aims to retrieve the most relevant video moment in an untrimmed video given a sentence description. Previous methods tend to perform self-modal learning and cross-modal interaction in a coarse manner, which neglect fine-grained clues contained in video content, query context, and their alignment. To this end, we propose a novel Multi-Granularity Perception Network (MGPN) that perceives intra-modality and inter-modality information at a multi-granularity level. Specifically, we formulate moment retrieval as a multi-choice reading comprehension task and integrate human reading strategies into our framework. A coarse-grained feature encoder and a co-attention mechanism are utilized to obtain a preliminary perception of intra-modality and inter-modality information. Then a fine-grained feature encoder and a conditioned interaction module are introduced to enhance the initial perception inspired by how humans address reading comprehension problems. Moreover, to alleviate the huge computation burden of some existing methods, we further design an efficient choice comparison module and reduce the hidden size with imperceptible quality loss. Extensive experiments on Charades-STA, TACoS, and ActivityNet Captions datasets demonstrate that our solution outperforms existing state-of-the-art methods. Codes are available at github.com/Huntersxsx/MGPN.
description: in SIGIR 2022
"Der Schritt vom Ritus zur Feier ist vollzogen"
Creators: name: Gerhards, Albert
name: Ruh, Ulrich
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 48 Nr. 12 (1994): Herder Korrespondenz, Band 48, Heft 12
Thermal devices powered by generalized measurements with indefinite causal order
Creators: name: Dieguez, Pedro R.
name: Lisboa, Vinicius F.
name: Serra, Roberto M.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A quantum-controlled device may produce a scenario in which two general quantum operations can be performed in such a way that it is not possible to associate a definite order for the operations application. Such an indefinite causal order can be explored to produce nontrivial effects in quantum thermal devices. We investigate a measurement-powered thermal device that consists of generalized measurement channels with adjustable intensity parameters, where energy is exchanged with the apparatus in the form of work or heat. The measurement-based device can operate as a heat engine, a thermal accelerator, or a refrigerator, according to a measurement intensity setting. By employing a quantum switch of two measurement channels, we explore a thermal device fueled by an indefinite causal order. We also discuss how a coherent control over an indefinite causal order structure can change the operating regimes of the measurement-powered thermal device to produce an advantage when compared to a scenario with an incoherent control of the order switch.
description: 14 pages, 9 figures, typos removed, closer to the published version
The role of ecosystem transpiration in creating alternate moisture regimes by influencing atmospheric moisture convergence
Creators: name: Makarieva, Anastassia M.
name: Nefiodov, Andrei V.
name: Nobre, Antonio Donato
name: Baudena, Mara
name: Bardi, Ugo
name: Sheil, Douglas
name: Saleska, Scott R.
name: Molina, Ruben D.
name: Rammig, Anja
Publisher: name: arXiv
Year: 2022
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: The terrestrial water cycle links the soil and atmosphere moisture reservoirs through four fluxes: precipitation, evaporation, runoff, and atmospheric moisture convergence (net import of water vapor to balance runoff). Each of these processes is essential for human and ecosystem well-being. Predicting how the water cycle responds to changes in vegetation cover remains a challenge. Recently, changes in plant transpiration across the Amazon basin were shown to be associated disproportionately with changes in rainfall, suggesting that even small declines in transpiration (e.g., from deforestation) would lead to much larger declines in rainfall. Here, constraining these results by the law of mass conservation, we show that in a sufficiently wet atmosphere, forest transpiration can control atmospheric moisture convergence such that increased transpiration enhances atmospheric moisture import and resulting water yield. Conversely, in a sufficiently dry atmosphere increased transpiration reduces atmospheric moisture convergence and water yield. This previously unrecognized dichotomy can explain the otherwise mixed observations of how water yield responds to re-greening, as we illustrate with examples from China's Loess Plateau. Our analysis indicates that any additional precipitation recycling by additional vegetation increases precipitation but decreases local water yield and steady-state runoff. Therefore, in the drier regions and early stages of ecological restoration, the role of vegetation can be confined to precipitation recycling, while once a wetter stage is achieved, additional vegetation enhances atmospheric moisture convergence and water yield. Evaluating the transition between regimes, and recognizing the potential of vegetation for enhancing moisture convergence, are crucial for characterizing the consequences of deforestation and for motivating and guiding ecological restoration.
description: 39 pages, 12 figures, 5 tables
Xeroderma pigmentosum complementation group C genotypes/diplotypes play no independent or interaction role with polycyclic aromatic hydrocarbons-DNA adducts for breast cancer risk
Creators: name: Terry, Mary Beth
name: Teitelbaum, Susan L.
name: Gammon, Marilie D.
name: Neugut, Alfred I.
name: Shen, Jing
name: Santella, Regina M.
name: Eng, Sybil M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Xeroderma pigmentosum complementation group C (XPC) is an important DNA nuclear excision repair (NER) gene that recognizes the damage caused by variety of bulky DNA adducts. We evaluated the association of two common non-synonymous polymorphisms in XPC (Ala499Val and Lys939Gln) with breast cancer risk in the Long Island Breast Cancer Study Project (LIBCSP), a population-based case-control study. Genotyping of 1,067 cases and 1,110 controls was performed by a high throughput assay with fluorescence polarization. There were no overall associations between XPC polymorphisms and breast cancer risk. A diplotype CC-CC was significantly associated with increased breast cancer risk compared with diplotype CA-CA (OR = 1.4, 95%CI: 1.0–1.9), but was not significant when compared with all other diplotypes combined (OR = 1.22, 95%CI: 0.97–1.53). No modification effects were observed for XPC genotypes by cigarette smoking status, smoking pack years or polycyclic aromatic hydrocarbons (PAH) DNA adducts. The increase in breast cancer risk was slightly more pronounced among women with detectable PAH-DNA adducts and carrying the diplotype CC-CC (OR = 1.6, 95%CI: 1.1–2.2) compared to women with non detectable PAH-DNA adducts carrying other diplotypes combined, but no statistically significant interaction was observed (P interaction = 0.69). These data suggest that XPC have neither independent effects nor interactions with cigarette smoking and PAH-DNA adducts for breast cancer risk. Further studies with multiple genetic polymorphisms in NER pathway are warranted.
The Role of Neuroplasticity in the Pathophysiology and Treatment of Mental Illness: A Comprehensive Literature Review
Creators: name: Thornton, Owen R
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Neuroplasticity is the brain's ability to change and adapt in response to internal and external stimuli. Through alterations in the number of neurons or glia, formation of new circuits, strengthening or weakening specific synapses, changing the number of dendritic spines, and/or other mechanisms, neuroplasticity contributes to dynamic and adaptive changes in synaptic strength [1][2]. However, impairments in neuroplasticity have been linked to the development of psychiatric and neurological disorders, including depression-like disorders [3][4]. In fact, reduced neurogenesis and synaptic plasticity are found in patients with major depressive disorder (MDD) [3]. Other studies have shown that abnormal neuroplasticity has been observed in individuals with MDD [4]. Reduced neuroplasticity can be attributed to the transcriptional regulation of genes involved in synaptic plasticity by epigenetic mechanisms [4]. This impairment contributes significantly towards the development of cognitive and affective symptoms associated with MDD [3]. Inducing or harnessing neuroplasticity has emerged as a promising treatment approach to counterbalance these maladaptive influences and alleviate symptomologies [3]. Developing novel methods of stimulating neuroplasticity may be an effective approach to complement current therapies for psychiatric disorders targeting neuroplasticity. However, there is still a need for further research on how neuroplasticity contributes to the development of mental illness. Nonetheless, identifying how neuroplasticity is regulated and altered in psychiatric disorders is necessary for developing treatments that target underlying abnormalities in neuroplasticity [3].
Manual therapists’ beliefs and use of spinal thrust joint manipulation
Creators: name: Hendrikus Antonius (Rik) Kranenburg
name: Schmitt, Maarten A.
name: Puentedura, Emilio J.
name: Van Der Schans, Cees P.
name: Heneghan, Nicola R.
name: Hutting, Nathan
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology

description: Thrust Joint Manipulation (TJM) is a widely used intervention in spinal care, however there are differences in its use between countries and spinal regions. This survey analyzes the frequency of use of TJM, examines the thoughts about the effectiveness of, and the perceptions of Dutch certified manual therapists regarding safety, comfort, use and barriers related to the application of spinal TJM techniques. The 19-question e-survey was based on a similar survey in the U.S. Since the Netherlands has a separate professional standard for the upper cervical spine, questions enabled differentiation between upper- and mid/lower cervical spine. The survey was launched during a national manual therapy congress and distributed via social media (April-July 2018). Descriptive analyses, MANOVA and qualitative analyses were used. From the 211 responses, 150 were male, with a mean age of 44.9 (±11.2) years, a mean clinical experience of 12.8 (±9.6) years as manual therapist, 87% had a master’s degree and 97% worked in a private practice. Except for the upper cervical spine, more than 80% of the participants felt that TJM was safe, were comfortable performing TJM. Overall >80% of participants perform additional screening prior to TJM. Concerns about safety is the greatest barrier for upper cervical TJM. Findings indicate that overall Dutch manual therapists believe TJM to be safe and effective and are comfortable performing them, except for the upper cervical spine, where concerns exist regarding safety and acquiring written informed consent. 2b.
Η χρήση πληροφοριακών συστημάτων ERP στην διαχείριση εφοδιαστικής αλυσίδας στους λιμένες. Μοντελοποίηση και προσομοίωση του συστήματος.
Creators: name: ΜΠΑΛΤΑΣΗΣ, ΑΝΑΣΤΑΣΙΟΣ
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2024
Subjects: subject: ERP
subject: ΛΙΜΕΝΕΣ
subject: Μοντελοποίηση και προσομοίωση του συστήματος ERP

description: Μ.Δ.Ε. 63
description: This paper seeks to investigate the implementation and use of Enterprise Resource Planning (ERP) and Logistics systems in Greek ports, analyzing in detail the benefits, challenges and prospects arising from the use of these systems. ERP and Logistics systems are essential management and process automation tools for modern businesses, as they allow for the integrated management of all functions of an organization through a single system. In particularly large and complex operations such as ports, the use of ERP and Logistics can have significant benefits in terms of simplifying and optimizing processes, reducing costs and increasing productivity. However, the implementation of these advanced systems requires significant investments and changes in port operations. Proper planning and training of staff, adaptation of legislation, interoperability between systems and a sound technical infrastructure are necessary. In addition, cooperation between stakeholders is an essential prerequisite for the correct implementation of ERP and logistics systems. The paper first focuses on the description and characteristics of ERP (Enterprise Resource Planning) systems. Through a survey, the challenges and opportunities of using Enterprise Resource Planning are identified. Finally, by using modeling, the functions of ERP are represented and different scenarios and results in the operation a port are studied. Keywords: ERP, Modelling and Simulation, Efficiency, Logistics
title: A comparison of two multiplex-PCR assays for the diagnosis of traveller’s diarrhoea
Creators: name: Schaumburg, Frieder
name: Froböse, Neele Judith
name: Köck, Robin
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2022
Subjects: subject: 610 Medicine and health

description: Background: Numerous multiplex-PCR assays are now available in routine diagnostics but their clinical value is controversial if a clear association between clinical symptoms and the detection of a particular pathogen is missing. The objective of this work was to evaluate a multiplex-PCR assay for the diagnosis of traveller’s diarrhoea (TD) in a case-control study and to assess the concordance with the BioFire® FilmArray® Gastrointestinal Panel. Methods: Stool samples from cases (n = 61) and controls (n = 30) were collected during travel and analysed by the GI-EB Screening assay (Seegene) in a case-control study. The concordance with the BioFire® FilmArray® Gastrointestinal Panel was expressed as the proportion of participants in which both tests agreed in the category "detected" and "not detected". Results: None of the test-target organisms ('Campylobacter' spp., 'Clostridioides difficile' toxin A/B, 'Salmonella' spp., 'Shigella' spp./enteroinvasive 'Escherichia coli', 'E. coli' O157, Shiga toxin-producing 'E. coli', 'Yersinia enterocolitica') was significantly associated with TD GI-EB Screening assay. The GI-EB Screening assay had an agreement with the BioFire® FilmArray® of 86.8–100%. Conclusion: The selection of test-target organisms included in the GI-EB Screening assay appears inappropriate for the diagnostic work-up of TD as none of the detected pathogens was associated with TD. The GI-EB Screening assay had a good concordance with BioFire® FilmArray®.
description: Finanziert über die DEAL-Vereinbarung mit Wiley 2019-2022.
On the coset graph construction of distance-regular graphs
Creators: name: Shi, Minjia
name: Krotov, Denis S.
name: Solé, Patrick
Publisher: name: arXiv
Year: 2022
Subjects: subject: Combinatorics (math.CO)
subject: Discrete Mathematics (cs.DM)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 05E30, 94B25

description: We show that no more new distance-regular graphs in the tables of the book of (Brouwer, Cohen, Neumaier, 1989) can be produced by using the coset graph of additive completely regular codes over finite fields.
Joint signature of two or more systems with applications to multistate systems made up of two-state components
Creators: name: Marichal, Jean-Luc
name: Mathonet, Pierre
name: Navarro, Jorge
name: Paroissin, Christian
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 62N05, 90B25, 94C10

description: The structure signature of a system made up of $n$ components having continuous and i.i.d. lifetimes was defined in the eighties by Samaniego as the $n$-tuple whose $k$-th coordinate is the probability that the $k$-th component failure causes the system to fail. More recently, a bivariate version of this concept was considered as follows. The joint structure signature of a pair of systems built on a common set of components having continuous and i.i.d. lifetimes is a square matrix of order $n$ whose $(k,l)$-entry is the probability that the $k$-th failure causes the first system to fail and the $l$-th failure causes the second system to fail. This concept was successfully used to derive a signature-based decomposition of the joint reliability of the two systems. In the first part of this paper we provide an explicit formula to compute the joint structure signature of two or more systems and extend this formula to the general non-i.i.d. case, assuming only that the distribution of the component lifetimes has no ties. We also provide and discuss a necessary and sufficient condition on this distribution for the joint reliability of the systems to have a signature-based decomposition. In the second part of this paper we show how our results can be efficiently applied to the investigation of the reliability and signature of multistate systems made up of two-state components. The key observation is that the structure function of such a multistate system can always be additively decomposed into a sum of classical structure functions. Considering a multistate system then reduces to considering simultaneously several two-state systems.
Comunicación digital: posibilidades y límites del entorno virtual
Creators: name: Salge, Manuel
Publisher: name: Universidad externado de colombia
Year: 2024

description: Objetivos Generales: * Comprende y reflexiona sobre la naturaleza comunicativa y relatora del ser humano en sus etapas de evolución y consolidación histórica de las primeras civilizaciones. * Apropia las formas constructivas del relato, los elementos constitutivos de la historia, los ejes circunstanciales y detonantes. * Desarrolla la escaleta de propuesta de historia, lugar, modo, tiempo, circunstancia y caracterización de los personajes.
description: El segundo módulo del Diplomado en Storytelling y narrativas transmedia explora los significados, los alcances, los desarrollos y las posibilidades narrativas del storytelling (el “arte” de contar historias), su origen, estructuras, funciones, enfoques, fórmulas, desarrollos, realizaciones y posibles aplicaciones en el campo de la comunicación, tanto a nivel periodístico como en el desarrollo de mensajes de estrategias corporativas. El enfoque del relato apela siempre a la emoción, la pasión, la identificación, el sentimiento, la admiración y el involucramiento de los públicos con las historias y sus protagonistas.
Dinámicas territoriales y turismo
Creators: name: Camargo Sierra, Angélica Patricia
Publisher: name: Universidad externado de colombia
Year: 2024

description: Objetivos Generales: * Analiza de manera integral las diferentes dimensiones del territorio: social, cultural, política, económica y ambiental, así como las dinámicas territoriales presentes en relación con la actividad turística, con el fin de comprender la relación entre el turismo y el territorio desde una perspectiva sistémica. * Comprende las características y los procesos territoriales diferenciados, propios de las diversas tipologías de los espacios: urbanos, regionales, rurales y naturales, de modo que pueda caracterizar las diferentes dinámicas turísticas que se dan en cada uno y las implicaciones en el territorio vistas desde un enfoque multiescalar. * Analiza críticamente, y mediante estrategias metodológicas rigurosas, las transformaciones e impactos territoriales asociados a las prácticas turísticas en un destino, con el objetivo de plantear propuestas de ordenamiento territorial orientadas a potenciar transformaciones e impactos positivos, y mitigar aquellos negativos.
description: El curso brinda herramientas teóricas y conceptuales para que los estudiantes puedan comprender y analizar las diferentes dimensiones del territorio, sus interacciones, sus dinámicas y procesos, así como las relaciones con la actividad turística, de modo que tengan la capacidad de analizar de manera crítica las implicaciones del turismo en el territorio, sus impactos y sus transformaciones, tanto en espacios naturales como urbanos y rurales. En tal sentido, el curso promoverá en los estudiantes una perspectiva comprensiva y propositiva sobre las transformaciones que pueden agenciarse para el desarrollo de un turismo que respete las dinámicas históricas, culturales, sociales y comunitarias presentes en los territorios.
Supplementary Material for Regulation strategies for two-output biomolecular networks
Creators: name: Alexis, Emmanouil
name: Schulte, Carolin C.M.
name: Cardelli, Luca
name: Papachristodoulou, Antonis
Publisher: name: The Royal Society
Year: 2023
Subjects: Systems Biology
Synthetic Biology
Biological Mathematics

description: Mathematical and Computational Analysis, Experimental Discussion
Investigation of Ensemble features of Self-Supervised Pretrained Models for Automatic Speech Recognition
Creators: name: Arunkumar, A
name: Sukhadia, Vrunda N
name: Umesh, S.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computation and Language (cs.CL)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Self-supervised learning (SSL) based models have been shown to generate powerful representations that can be used to improve the performance of downstream speech tasks. Several state-of-the-art SSL models are available, and each of these models optimizes a different loss which gives rise to the possibility of their features being complementary. This paper proposes using an ensemble of such SSL representations and models, which exploits the complementary nature of the features extracted by the various pretrained models. We hypothesize that this results in a richer feature representation and shows results for the ASR downstream task. To this end, we use three SSL models that have shown excellent results on ASR tasks, namely HuBERT, Wav2vec2.0, and WaveLM. We explore the ensemble of models fine-tuned for the ASR task and the ensemble of features using the embeddings obtained from the pre-trained models for a downstream ASR task. We get improved performance over individual models and pre-trained features using Librispeech(100h) and WSJ dataset for the downstream tasks.
description: 4 pages , 2 figures,submitted to interspeech 2022
Mirror Symmetry in Emergent Gravity
Creators: name: Yang, Hyun Seok
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Differential Geometry (math.DG)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Given a six-dimensional symplectic manifold $(M, B)$, a nondegenerate, co-closed four-form $C$ introduces a dual symplectic structure $\widetilde{B} = *C $ independent of $B$ via the Hodge duality $*$. We show that the doubling of symplectic structures due to the Hodge duality results in two independent classes of noncommutative U(1) gauge fields by considering the Seiberg-Witten map for each symplectic structure. As a result, emergent gravity suggests a beautiful picture that the variety of six-dimensional manifolds emergent from noncommutative U(1) gauge fields is doubled. In particular, the doubling for the variety of emergent Calabi-Yau manifolds allows us to arrange a pair of Calabi-Yau manifolds such that they are mirror to each other. Therefore, we argue that the mirror symmetry of Calabi-Yau manifolds is the Hodge theory for the deformation of symplectic and dual symplectic structures.
description: v4; 20 pages, version to appear in Nucl. Phys. B
Amplification of thymidylate synthetase in metastatic colorectal cancer patients pretreated with 5-fluorouracil-based chemotherapy
Creators: name: Muhale, Filipe
name: Auman, James T.
name: Hoskins, Janelle M.
name: Meyers, Michael O.
name: O’Neil, Bert H.
name: Thorne, Leigh B.
name: Watson, Roshawn G.
name: Deal, Allison M.
name: Ibrahim, Joseph G.
name: Walko, Christine M.
name: Yu, Jinsheng
name: McLeod, Howard L.
name: Hudson, Michael L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Resistance to 5-fluorouracil (5-FU) represents a major contributor to cancer-related mortality in advanced colorectal cancer patients. Genetic variations and expression alterations in genes involved in 5-FU metabolism and effect have been shown to modulate 5-FU sensitivity in vitro, however these alterations do not fully explain clinical resistance to 5-FU-based chemotherapy. To determine if alterations of DNA copy number in genes involved in 5-FU metabolism impacted clinical resistance to 5-FU-based chemotherapy, we assessed thymidylate synthetase (TYMS) and thymidine phosphorylase (TYMP) copy number in colorectal liver metastases. DNA copy number of TYMS and TYMP was evaluated using real time quantitative PCR in frozen colorectal liver metastases procured from 62 patients who were pretreated with 5-FU-based chemotherapy prior to surgical resection (5-FU exposed) and from 51 patients who received no pretreatment (unexposed). Gain of TYMS DNA copy number was observed in 18% of the 5-FU exposed metastases, while only 4% of the unexposed metastases exhibited TYMS copy gain (p=0.036). No significant differences were noted in TYMP copy number alterations between 5-FU exposed and unexposed metastases. Median survival time was similar in 5-FU exposed patients with metastases containing TYMS amplification and those with no amplification. However, TYMS amplification was associated with shorter median survival in patients receiving post-resection chemotherapy (hazard ratio = 2.7, 95% confidence interval = 1.1 to 6.6; p=0.027). These results suggest amplification of TYMS amplification as a putative mechanism for clinical resistance to 5-FU-based chemotherapy and may have important ramifications for the post-resection chemotherapy choices for metastatic colorectal cancer.