cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Confidence-based Somatic Mutation Evaluation and Prioritization
Creators: name: Löwer, Martin
name: Renard, Bernhard Y.
name: Graaf, Jos De
name: Wagner, Meike
name: Paret, Claudia
name: Kneip, Christoph
name: Türeci, Özlem
name: Diken, Mustafa
name: Britten, Cedrik
name: Kreiter, Sebastian
name: Koslowski, Michael
name: Castle, John C.
name: Sahin, Ugur
Publisher: name: Robert Koch-Institut
Year: 2012
Subjects: subject: Animals
subject: Mice
subject: Sensitivity and Specificity
subject: Reproducibility of Results
subject: Melanoma/genetics
subject: Sequence Analysis DNA/methods
subject: Mice Inbred C57BL
subject: Mutation/genetics
subject: Artifacts
subject: DNA Mutational Analysis/methods
subject: DNA Neoplasm/genetics
subject: Exome/genetics
subject: False Positive Reactions
subject: 610 Medizin

description: Next generation sequencing (NGS) has enabled high throughput discovery of somatic mutations. Detection depends on experimental design, lab platforms, parameters and analysis algorithms. However, NGS-based somatic mutation detection is prone to erroneous calls, with reported validation rates near 54% and congruence between algorithms less than 50%. Here, we developed an algorithm to assign a single statistic, a false discovery rate (FDR), to each somatic mutation identified by NGS. This FDR confidence value accurately discriminates true mutations from erroneous calls. Using sequencing data generated from triplicate exome profiling of C57BL/6 mice and B16-F10 melanoma cells, we used the existing algorithms GATK, SAMtools and SomaticSNiPer to identify somatic mutations. For each identified mutation, our algorithm assigned an FDR. We selected 139 mutations for validation, including 50 somatic mutations assigned a low FDR (high confidence) and 44 mutations assigned a high FDR (low confidence). All of the high confidence somatic mutations validated (50 of 50), none of the 44 low confidence somatic mutations validated, and 15 of 45 mutations with an intermediate FDR validated. Furthermore, the assignment of a single FDR to individual mutations enables statistical comparisons of lab and computation methodologies, including ROC curves and AUC metrics. Using the HiSeq 2000, single end 50 nt reads from replicates generate the highest confidence somatic mutation call set.
sj-docx-1-jht-10.1177_10963480211012459 – Supplemental material for Creative Atmosphere in Creative Tourism Destinations: Conceptualizing and Scale Development
Creators: name: Cheng, Tien-Ming
name: Chen, Mei-Tsun
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 150402 Hospitality Management

description: Supplemental material, sj-docx-1-jht-10.1177_10963480211012459 for Creative Atmosphere in Creative Tourism Destinations: Conceptualizing and Scale Development by Tien-Ming Cheng and Mei-Tsun Chen in Journal of Hospitality & Tourism Research
sj-docx-1-psp-10.1177_01461672211024422 – Supplemental material for Does Respect Foster Tolerance? (Re)analyzing and Synthesizing Data From a Large Research Project Using Meta-Analytic Techniques
Creators: name: Zitzmann, Steffen
name: Loreth, Lukas
name: Reininger, Klaus Michael
name: Simon, Bernd
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-psp-10.1177_01461672211024422 for Does Respect Foster Tolerance? (Re)analyzing and Synthesizing Data From a Large Research Project Using Meta-Analytic Techniques by Steffen Zitzmann, Lukas Loreth, Klaus Michael Reininger and Bernd Simon in Personality and Social Psychology Bulletin
Intrinsic Magnetic Topological Materials
Creators: name: Wang, Yuan
name: Zhang, Fayuan
name: Zeng, Meng
name: Sun, Hongyi
name: Hao, Zhanyang
name: Cai, Yongqing
name: Rong, Hongtao
name: Zhang, Chengcheng
name: Liu, Cai
name: Ma, Xiaoming
name: Wang, Le
name: Guo, Shu
name: Lin, Junhao
name: Liu, Qihang
name: Liu, Chang
name: Chen, Chaoyu
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Topological states of matter possess bulk electronic structures categorized by topological invariants and edge/surface states due to the bulk-boundary correspondence. Topological materials hold great potential in the development of dissipationless spintronics, information storage, and quantum computation, particularly if combined with magnetic order intrinsically or extrinsically. Here, we review the recent progress in the exploration of intrinsic magnetic topological materials, including but not limited to magnetic topological insulators, magnetic topological metals, and magnetic Weyl semimetals. We pay special attention to their characteristic band features such as the gap of topological surface state, gapped Dirac cone induced by magnetization (either bulk or surface), Weyl nodal point/line, and Fermi arc, as well as the exotic transport responses resulting from such band features. We conclude with a brief envision for experimental explorations of new physics or effects by incorporating other orders in intrinsic magnetic topological materials.
description: 32 pages, 15 figures
CAMCR: Computer-assisted mixture model analysis for capture-recapture count data
Creators: name: Kuhnert, Ronny
name: Böhning, Dankmar
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2008
Subjects: subject: CAMCR
subject: Capture–recapture
subject: Chao’s and Zelterman’s estimator of population size
subject: Mixture of truncated Poisson distributions
subject: 610 Medizin

description: Population size estimation with discrete or nonparametric mixture models is considered, and reliable ways of construction of the nonparametric mixture model estimator are reviewed and set into perspective. Construction of the maximum likelihood estimator of the mixing distribution is done for any number of components up to the global nonparametric maximum likelihood bound using the EM algorithm. In addition, the estimators of Chao and Zelterman are considered with some generalisations of Zelterman’s estimator. All computations are done with CAMCR, a special software developed for population size estimation with mixture models. Several examples and data sets are discussed and the estimators illustrated. Problems using the mixture model-based estimators are highlighted.
Plan de Gestión de Datos. Proyecto de Investigación Doctoral. Versión 1.0
Creators: name: Ruz-Fuenzalida, Carlos
Publisher: name: Zenodo
Year: 2025
Subjects: plan de gestión
proceso de investigación
calidad de investigación

description: Instrumento complementario en el proyecto de investigación doctoral sobre análisis de transferencia de política pública entre los programas "Chile Crece Contigo" y "Uruguay Crece Contigo".
Methicillin-resistant Staphylococcus aureus in Europe, 1999–2002
Creators: name: Tiemersma, Edine W.
name: Bronzwaer, Stef L.A.M.
name: Lyytikäinen, Outi
name: Degener, John E.
name: Schrijnemakers, Paul
name: Bruinsma, Nienke
name: Monen, Jos
name: Witte, Wolfgang
name: Grundmann, Hajo
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2004
Subjects: subject: Humans
subject: Prevalence
subject: Population Surveillance
subject: Europe/epidemiology
subject: Quality Assurance
subject: Health Care
subject: Methicillin Resistance
subject: Staphylococcus aureus/drug effects
subject: Staphylococcal Infections/epidemiology
subject: Staphylococcal Infections/microbiology
subject: International Cooperation
subject: 610 Medizin

description: We explored the variation in proportions of methicillin-resistant Staphylococcus aureus (MRSA) between and within countries participating in the European Antimicrobial Resistance Surveillance System and temporal trends in its occurrence. This system collects routine antimicrobial susceptibility tests for S. aureus. We examined data collected from January 1999 through December 2002 (50,759 isolates from 495 hospitals in 26 countries). MRSA prevalence varied almost 100-fold, from 40% in southern and western Europe. MRSA proportions significantly increased in Belgium, Germany, Ireland, the Netherlands, and the United Kingdom, and decreased in Slovenia. Within countries, MRSA proportions varied between hospitals with highest variance in countries with a prevalence of 5% to 20%. The observed trends should stimulate initiatives to control MRSA at national, regional, and hospital levels. The large differences between hospitals indicate that efforts may be most effective at regional and hospital levels.
Immunity status of adults and children against poliomyelitis virus type 1 strains CHAT and Sabin (LSc-2ab) in Germany
Creators: name: Eggers, Maren
name: Terletskaia-Ladwig, Elena
name: Rabenau, Holger F.
name: Doerr, Hans W.
name: Diedrich, Sabine
name: Enders, Gisela
name: Enders, Martin
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2010
Subjects: subject: Adult
subject: Humans
subject: Germany
subject: Child
subject: Antibodies
subject: Infant
subject: Neutralization Tests
subject: Child Preschool
subject: Antibodies Viral/blood
subject: Poliomyelitis/immunology
subject: Poliomyelitis/prevention & control
subject: Poliovirus/immunology
subject: Neutralizing/blood
subject: Poliomyelitis/virology
subject: Poliovirus Vaccines/immunology
subject: 610 Medizin

description: Background: In October 2007, the working group CEN/TC 216 of the European Committee for standardisation suggested that the Sabin oral poliovirus vaccine type 1 strain (LSc-2ab) presently used for virucidal tests should be replaced by another attenuated vaccine poliovirus type 1 strain, CHAT. Both strains were historically used as oral vaccines, but the Sabin type 1 strain was acknowledged to be more attenuated. In Germany, vaccination against poliomyelitis was introduced in 1962 using the oral polio vaccine (OPV) containing Sabin strain LSc-2ab. The vaccination schedule was changed from OPV to an inactivated polio vaccine (IPV) containing wild polio virus type 1 strain Mahoney in 1998. In the present study, we assessed potential differences in neutralising antibody titres to Sabin and CHAT in persons with a history of either OPV, IPV, or OPV with IPV booster. Methods: Neutralisation poliovirus antibodies against CHAT and Sabin 1 were measured in sera of 41 adults vaccinated with OPV. Additionally, sera from 28 children less than 10 years of age and immunised with IPV only were analysed. The neutralisation assay against poliovirus was performed according to WHO guidelines. Results: The neutralisation activity against CHAT in adults with OPV vaccination history was significantly lower than against Sabin poliovirus type 1 strains (Wilcoxon signed-rank test P < 0.025). In eight sera, the antibody titres measured against CHAT were less than 8, although the titre against Sabin 1 varied between 8 and 64. Following IPV booster, anti-CHAT antibodies increased rapidly in sera of CHAT-negative adults with OPV history. Sera from children with IPV history neutralised CHAT and Sabin 1 strains equally. Conclusion: The lack of neutralising antibodies against the CHAT strain in persons vaccinated with OPV might be associated with an increased risk of reinfection with the CHAT polio virus type 1, and this implies a putative risk of transmission of the virus to polio-free communities. We strongly suggest that laboratory workers who were immunised with OPV receive a booster vaccination with IPV before handling CHAT in the laboratory.
Salmonella Agona Outbreak from Contaminated Aniseed, Germany
Creators: name: Koch, Judith
name: Schrauder, Annette
name: Alpers, Katharina
name: Werber, Dirk
name: Frank, Christina
name: Prager, Rita
name: Rabsch, Wolfgang
name: Broll, Susanne
name: Feil, Fabian
name: Roggentin, Peter
name: Bockemühl, Jochen
name: Tschäpe, Helmut
name: Ammon, Andrea
name: Stark, Klaus
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2005
Subjects: subject: Humans
subject: Disease Outbreaks
subject: Germany/epidemiology
subject: Salmonella Food Poisoning/epidemiology
subject: Food Microbiology
subject: Infant
subject: Salmonella Food Poisoning/microbiology
subject: Beverages/microbiology
subject: Pimpinella/microbiology
subject: Salmonella enterica/classification
subject: Salmonella enterica/isolation & purification
subject: Seeds/microbiology
subject: 610 Medizin

description: A nationwide outbreak of Salmonella Agona caused by aniseed-containing herbal tea occurred from October 2002 through July 2003 among infants in Germany. Consumers should adhere strictly to brewing instructions, although in exceptional cases this precaution may not be protective, particularly when preparing tea for vulnerable age groups.
Impact of a family-oriented rehabilitation programme on behavioural and emotional problems in healthy siblings of chronically ill children
Creators: name: Besier, Tanja
name: Hölling, Heike
name: Schlack, Robert
name: West, C.
name: Goldbeck, L.
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2010
Subjects: subject: Adolescent
subject: Humans
subject: Female
subject: Male
subject: Child
subject: Questionnaires
subject: Chronic Disease/psychology
subject: Mental Health
subject: Child Preschool
subject: Program Evaluation
subject: Parent-Child Relations
subject: Family Relations
subject: Family Therapy/methods
subject: Health Knowledge- Attitudes- Practice
subject: Mental Disorders/rehabilitation
subject: Parents/psychology
subject: Siblings/psychology
subject: 610 Medizin

description: Objective: To evaluate the impact of a family-oriented inpatient rehabilitation programme on behavioural and emotional problems in healthy siblings of chronically ill children and to assess the association between these problems and quality of life. Methods: A total of 259 healthy children (4–16 years,M = 8.6 years, SD = 3.3) with a chronically ill sibling were enrolled in the study. Parents filled in the Strengths and Difficulties Questionnaire, while the children answered a self-report quality of life instrument (LQ-KID) at the time of admission and discharge from the clinic and at a 6-month follow-up. Comparisons were performed with a matched control group from the German general population (n = 777). Results: Significant behavioural or emotional symptoms were found in 30.5% of the healthy siblings, the relative risk of having elevated scores being 2.2 compared with the control group. Symptoms were inversely correlated with quality of life (r = -0.42). During the inpatient rehabilitation, symptoms decreased significantly to a normal level. Similarly, quality of life significantly improved, except in the dimension family relations. Conclusions: Family-oriented inpatient rehabilitation is a promising approach to improve the mental health of children with a chronically ill sibling.
Paternidade e Cuidado: aspecto teórico e conceitual
Creators: name: Costa SF, SIMONI
name: Santiago, Daniel
name: Lucena, Giovana
name: Namink, Giulie
name: Bezerra, Melissa
name: Lins, Victoria
Publisher: name: Zenodo
Year: 2025

description: Trata-se de um informativo produzido e distribuído pela equipe do projeto de extensão “Pai Presente” e Prodocência: "Paternidade em formação: acolhimento, cuidado e acesso à saúde"(Edital UERJ nº 35/2021). O material tem como propósito informar a população sobre os direitos do homem e promover o incentivo à paternidade ativa. Os projetos são vinculados ao Departamento de Enfermagem materno-infantil da Faculdade de Enfermagem da UERJ.
Supplemental Material, sj-pdf-1-jic-10.1177_08850666211023360 - Outcomes of Barotrauma in Critically Ill COVID-19 Patients With Severe Pneumonia
Creators: name: Gazivoda, Victor P.
name: Ibrahim, Mudathir
name: Kangas-Dick, Aaron
name: Sun, Arony
name: Silver, Michael
name: Wiesel, Ory
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 110203 Respiratory Diseases

description: Supplemental Material, sj-pdf-1-jic-10.1177_08850666211023360 for Outcomes of Barotrauma in Critically Ill COVID-19 Patients With Severe Pneumonia by Victor P. Gazivoda, Mudathir Ibrahim, Aaron Kangas-Dick, Arony Sun, Michael Silver and Ory Wiesel in Journal of Intensive Care Medicine
Additional file 1 of Association between alcohol consumption and risk of stroke among adults: results from a prospective cohort study in Chongqing, China
Creators: name: Liu, Xin
name: Ding, Xianbin
name: Zhang, Fan
name: Chen, Liling
name: Luo, Qinwen
name: Xiao, Meng
name: Liu, Xiang
name: Wu, Yunyun
name: Tang, Wenge
name: Qiu, Jingfu
name: Tang, Xiaojun
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Supplementary Material 1
A Intervenção E Estabilização De Edifícios Históricos Pós-Sismo
Creators: name: Marsella, Stefano
Publisher: name: Zenodo
Year: 2018
Subjects: earthquake
cultural heritage
procedures
innovation technologies
laser scanner
shorings

description: The presentation, held in the framework of the "Jornadas internacionais de Risco de incendio no patrimonio Cultural"  is aimed at giving some information about the organisation that Italy has defined in order to deal with large scale disasters involving Cultural Heritage buildings. The main topics dealt in the presentation are: the "red zone concept", how to let firefighters put in safety conditions movable and immovable objects that normally can be cared only by specific Cultural heritage experts.

In such framework, innovation technologies can help first responders in assessing with more confidence the static safety situation of the buildings damaged by the earthquakes. The H2020 STORM project is helping the CNVVF in identifying the most suitable technologies to be used in the aftermath of an even.
Additional file 6 of Comparative efficacy of oral drugs for chronic radiation proctitis — a systematic review
Creators: name: Liu, Liangzhe
name: Xiao, Nana
name: Liang, Jinjun
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy

description: Additional file 6.
Pré-natal do parceiro e paternidade e cuidado
Creators: name: FURTADO DA COSTA, SIMONI
name: Namink, Giulie
name: Santiago, Daniel
name: Lins, Victoria
name: Bezerra, Melissa
name: Lucena, Giovana
Publisher: name: Zenodo
Year: 2025

description: Trata-se de um informativo produzido pela equipe do projeto de extensão “Pai Presente” e Prodocência: "Paternidade em formação: acolhimento, cuidado e acesso à saúde"(Edital UERJ nº 35/2021). O material tem como propósito informar a população sobre os direitos do homem e promover o incentivo à paternidade ativa. Os projetos são vinculados ao Departamento de Enfermagem materno-infantil da Faculdade de Enfermagem da UERJ.
Supplemental Material, sj-pdf-1-aja-10.1177_15333175211025911 - Preliminary Validation of the Triana Test: A New Story Recall Test Based on Emotional Material
Creators: name: Luque-Tirado, Andrea
name: Rodrigo-Herrero, Silvia
name: Sánchez-Arjona, María Bernal
name: Franco-Macías, Emilio
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material, sj-pdf-1-aja-10.1177_15333175211025911 for Preliminary Validation of the Triana Test: A New Story Recall Test Based on Emotional Material by Andrea Luque-Tirado, Silvia Rodrigo-Herrero, María Bernal Sánchez-Arjona and Emilio Franco-Macías in American Journal of Alzheimer's Disease & Other Dementias
Strengthening malaria control through seasonal malaria chemoprevention campaign in Guinea-Bissau
Creators: name: Rocaspana, Mercè
name: Dakitche Lawoe Houedakor
name: Villen, Susana
Publisher: name: F1000Research
Year: 2017

description: In Guinea-Bissau, malaria is the leading morbidity and cause of mortality due to diseases in children under 5 years old. To reduce this, MSF has designed the Seasonal Malaria Chemoprevention (SMC) in the Bafatá region of Guinea-Bissau. This implementation was the first in Guinea-Bissau to have a good outcome, and MSF has trained staff in other regions in order to expand this further.
Additional file 1 of Amorphous silica nanoparticles cause abnormal cytokinesis and multinucleation through dysfunction of the centralspindlin complex and microfilaments
Creators: name: Xiao, Liyan
name: Pang, Jinyan
name: Qin, Hua
name: Dou, Liyang
name: Yang, Man
name: Wang, Ji
name: Zhou, Xianqing
name: Li, Yang
name: Duan, Junchao
name: Sun, Zhiwei
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Figure 1. Morphology and particle size of aSiNPs. (A) TEM images. (B) Average size and size distribution. Both two sizes aSiNPs possessed spherical or ellipsoidal shape and the average sizes measured by Image J software were 64 and 46 nm, respectively.
Supplemental Material, sj-docx-1-ang-10.1177_00033197211021199 - Association Between White Blood Cell Counts and Brachial-Ankle Pulse Wave Velocity in Chinese Hypertensive Adults: A Cross-Sectional Study
Creators: name: Jia, Buyun
name: Jiang, Chongfei
name: Song, Yun
name: Duan, Chenfangyuan
name: Liu, Lishun
name: Liu, Chengzhang
name: Xu, Xiping
name: Qin, Xianhui
name: Chen, Guangliang
Publisher: name: SAGE Journals
Year: 2021
Subjects: Cardiology

description: Supplemental Material, sj-docx-1-ang-10.1177_00033197211021199 for Association Between White Blood Cell Counts and Brachial-Ankle Pulse Wave Velocity in Chinese Hypertensive Adults: A Cross-Sectional Study by Buyun Jia, Chongfei Jiang, Yun Song, Chenfangyuan Duan, Lishun Liu, Chengzhang Liu, Xiping Xu, Xianhui Qin and Guangliang Chen in Angiology
Explicit Abnormality Extraction for Unsupervised Motion Artifact Reduction in Magnetic Resonance Imaging
Creators: name: Zhou, Yusheng
name: Li, Hao
name: Liu, Jianan
name: Kong, Zhengmin
name: Huang, Tao
name: Ahn, Euijoon
name: Lv, Zhihan
name: Kim, Jinman
name: Feng, David Dagan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Medical Physics (physics.med-ph)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: Motion artifacts compromise the quality of magnetic resonance imaging (MRI) and pose challenges to achieving diagnostic outcomes and image-guided therapies. In recent years, supervised deep learning approaches have emerged as successful solutions for motion artifact reduction (MAR). One disadvantage of these methods is their dependency on acquiring paired sets of motion artifact-corrupted (MA-corrupted) and motion artifact-free (MA-free) MR images for training purposes. Obtaining such image pairs is difficult and therefore limits the application of supervised training. In this paper, we propose a novel UNsupervised Abnormality Extraction Network (UNAEN) to alleviate this problem. Our network is capable of working with unpaired MA-corrupted and MA-free images. It converts the MA-corrupted images to MA-reduced images by extracting abnormalities from the MA-corrupted images using a proposed artifact extractor, which intercepts the residual artifact maps from the MA-corrupted MR images explicitly, and a reconstructor to restore the original input from the MA-reduced images. The performance of UNAEN was assessed by experimenting with various publicly available MRI datasets and comparing them with state-of-the-art methods. The quantitative evaluation demonstrates the superiority of UNAEN over alternative MAR methods and visually exhibits fewer residual artifacts. Our results substantiate the potential of UNAEN as a promising solution applicable in real-world clinical environments, with the capability to enhance diagnostic accuracy and facilitate image-guided therapies. Our codes are publicly available at https://github.com/YuSheng-Zhou/UNAEN.
description: Accepted by IEEE Journal of Biomedical and Health Informatics
Malaria vector studies to determine MSF’s strategy for malaria vector control in the Democratic Republic of Congo (DRC)
Creators: name: Loonen, Jeanine A.C.M.
name: Dery, Dominic B.
name: Musaka, Bertin Z.
name: Janvier B. Bandibabone
name: Pop-Stefanija, Biserka
name: Fesselet, Jean Francois
name: Constantianus J.M. Koenraadt
Publisher: name: F1000Research
Year: 2017

description: In 2012, MSF initiated several studies to better understand incidence of Malaria in the Democratic Republic of Congo (DRC), which remained an increasing health problem in this country. An integrative study was set-up to evaluate the main vector species involved in transmission, susceptibility towards insecticides and the effectiveness of treated nets. This poster talks about the best strategy for MSF to control malaria mosquitoes.
Additional file 1 of Jatrophone: a cytotoxic macrocylic diterpene targeting PI3K/AKT/NF-κB pathway, inducing apoptosis and autophagy in resistant breast cancer cells
Creators: name: Shari, Khawlah
name: El Gedaily, Rania A.
name: Allam, Rasha M.
name: Meselhy, Khaled M.
name: Khaleel, Amal E.
name: Abdel-Sattar, Essam
Publisher: name: figshare
Year: 2024
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Plant Biology
subject: FOS: Biological sciences

description: Supplementary Material 1
Supplementary Material from Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades
Creators: name: Dutta, Soumi
name: Hering, Lars
name: Grollmann, Milena M.
name: Metzendorf, Niklas
name: Gross, Vladimir
name: Arakawa, Kazuharu
name: Neupert, Susanne
name: Stengl, Monika
name: Herberg, Friedrich
name: Mayer, Georg
Publisher: name: The Royal Society
Year: 2025
Subjects: classificationCode: 320999
subject: Neurosciences not elsewhere classified

description: suppl_figure_3.pdf
Epidemiological investigation of suspected sepsis/meningitis outbreak in neonatal ward, Mweso, DRC
Creators: name: Althomsons, Sandy
name: Siddiqui, Ruby
name: Roggeveen, Harriet
name: Ouabo, Adelaide
name: Wit, Marit De
Publisher: name: F1000Research
Year: 2017

description: MSF returned back to Mweso, Democratic Republic of Congo, in 2016 and since noticed a high mortality in the neonatal ward. Having suspected a meningitis outbreak, epidemiological investigations found that 29% of neonates were admitted to the ward without good indication. In addition to this, different investigations found that there was in fact, no indication of a meningitis/sepsis outbreak. Improved training and supervision are being implemented.
Supplementary Material from Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades
Creators: name: Dutta, Soumi
name: Hering, Lars
name: Grollmann, Milena M.
name: Metzendorf, Niklas
name: Gross, Vladimir
name: Arakawa, Kazuharu
name: Neupert, Susanne
name: Stengl, Monika
name: Herberg, Friedrich
name: Mayer, Georg
Publisher: name: The Royal Society
Year: 2025
Subjects: classificationCode: 320999
subject: Neurosciences not elsewhere classified

description: suppl_tables_S1_S6.docx
MPEC 2024-H20 : COMET C/2024 G2 (ATLAS)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: COMET C/2024 G2 (ATLAS)

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Supplemental Material, sj-pdf-1-vet-10.1177_03009858211020670 - Pathogenesis of Equid Alphaherpesvirus 1 Infection in the Central Nervous System of Mice
Creators: name: Mesquita, Leonardo P.
name: Costa, Rafael C.
name: Mesquita, Laís L. R.
name: Lara, Maria do Carmo C. S. H.
name: Villalobos, Eliana M. C.
name: Mori, Claudia M. C.
name: Mori, Enio
name: Howerth, Elizabeth W.
name: Maiorka, Paulo C.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental Material, sj-pdf-1-vet-10.1177_03009858211020670 for Pathogenesis of Equid Alphaherpesvirus 1 Infection in the Central Nervous System of Mice by Leonardo P. Mesquita, Rafael C. Costa, Laís L. R. Mesquita, Maria do Carmo C. S. H. Lara, Eliana M. C. Villalobos, Claudia M. C. Mori, Enio Mori, Elizabeth W. Howerth and Paulo C. Maiorka in Veterinary Pathology
Supplementary Material from Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades
Creators: name: Dutta, Soumi
name: Hering, Lars
name: Grollmann, Milena M.
name: Metzendorf, Niklas
name: Gross, Vladimir
name: Arakawa, Kazuharu
name: Neupert, Susanne
name: Stengl, Monika
name: Herberg, Friedrich
name: Mayer, Georg
Publisher: name: The Royal Society
Year: 2025
Subjects: classificationCode: 320999
subject: Neurosciences not elsewhere classified

description: suppl_figure_7.pdf
Informing policy via dynamic models: Cholera in Haiti
Creators: name: Wheeler, Jesse
name: Rosengart, AnnaElaine
name: Jiang, Zhuoxun
name: Tan, Kevin
name: Treutle, Noah
name: Ionides, Edward
Publisher: name: arXiv
Year: 2023
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: Public health decisions must be made about when and how to implement interventions to control an infectious disease epidemic. These decisions should be informed by data on the epidemic as well as current understanding about the transmission dynamics. Such decisions can be posed as statistical questions about scientifically motivated dynamic models. Thus, we encounter the methodological task of building credible, data-informed decisions based on stochastic, partially observed, nonlinear dynamic models. This necessitates addressing the tradeoff between biological fidelity and model simplicity, and the reality of misspecification for models at all levels of complexity. We assess current methodological approaches to these issues via a case study of the 2010-2019 cholera epidemic in Haiti. We consider three dynamic models developed by expert teams to advise on vaccination policies. We evaluate previous methods used for fitting these models, and we demonstrate modified data analysis strategies leading to improved statistical fit. Specifically, we present approaches for diagnosing model misspecification and the consequent development of improved models. Additionally, we demonstrate the utility of recent advances in likelihood maximization for high-dimensional nonlinear dynamic models, enabling likelihood-based inference for spatiotemporal incidence data using this class of models. Our workflow is reproducible and extendable, facilitating future investigations of this disease system.
description: To be submitted to Plos Comp Bio
Measurement-efficient quantum Krylov subspace diagonalisation
Creators: name: Zhang, Zongkang
name: Wang, Anbang
name: Xu, Xiaosi
name: Li, Ying
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The Krylov subspace methods, being one category of the most important classical numerical methods for linear algebra problems, can be much more powerful when generalised to quantum computing. However, quantum Krylov subspace algorithms are prone to errors due to inevitable statistical fluctuations in quantum measurements. To address this problem, we develop a general theoretical framework to analyse the statistical error and measurement cost. Based on the framework, we propose a quantum algorithm to construct the Hamiltonian-power Krylov subspace that can minimise the measurement cost. In our algorithm, the product of power and Gaussian functions of the Hamiltonian is expressed as an integral of the real-time evolution, such that it can be evaluated on a quantum computer. We compare our algorithm with other established quantum Krylov subspace algorithms in solving two prominent examples. To achieve an error comparable to that of the classical Lanczos algorithm at the same subspace dimension, our algorithm typically requires orders of magnitude fewer measurements than others. Such an improvement can be attributed to the reduced cost of composing projectors onto the ground state. These results show that our algorithm is exceptionally robust to statistical fluctuations and promising for practical applications.
description: 29 pages, 9 figures
Two-population Bayesian hierarchical model of type Ia supernovae
Creators: name: Wojtak, Radosław
name: Hjorth, Jens
name: Hjortlund, Jacob Osman
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The currently used standardisation of type Ia supernovae results in Hubble residuals whose physical origin is unaccounted for. Here, we present a complete physical interpretation of the Hubble residuals based on a novel Bayesian hierarchical model of type Ia supernovae in which latent variables describing intrinsic and extrinsic (dust related) supernova properties originate from two populations. Fitting the model to SALT2 light curve parameters of supernovae in the Hubble flow we find strong ($4σ$) evidence for the presence of two overlapping, but distinct, populations differentiated primarily by their mean SALT2 shape parameter (stretch) x_1. Supernovae from the population with predominantly slow decliners (higher average x_1) are found to be intrinsically bluer (mean SALT2 colour c=-0.11) and twice as reddened by dust (mean reddening E(B-V)=0.10) than those from the opposite population dominated by fast decliners (lower average x_1) with c=-0.04$ and E(B-V)=0.05. The inferred extinction coefficient R_B in both supernova populations follows a broad (scatter 0.9) distribution with a mean of 4.1, which coincides closely with the mean extinction law measured in the Milky Way. We also find that the supernova data favour a peaked (two-tailed) distribution of selective extinction E(B-V) over the commonly adopted exponential model (one-tailed with maximum fixed at 0). Our model provides a complete explanation of the distribution of supernova light curve parameters in terms of extinction properties and the above-mentioned differences between the two populations, without the need for introducing any intrinsic scatter.
description: 19 pages, 6 figures, 3 tables; accepted for publication in MNRAS
sj-pdf-3-opp-10.1177_10781552211023571 - Supplemental material for Evaluation of external contamination on the vial surfaces of some hazardous drugs that commonly used in Chinese hospitals and comparison between environmental contamination generated during robotic compounding by IV: Dispensing robot vs. manual compounding in biological safety cabinet
Creators: name: ML, Hao
name: T, Wang
name: JQ, Zhu
name: YJ, Song
name: TJ, Gong
name: LK, Zou
name: J, Liu
name: JF, Yan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-pdf-3-opp-10.1177_10781552211023571 for Evaluation of external contamination on the vial surfaces of some hazardous drugs that commonly used in Chinese hospitals and comparison between environmental contamination generated during robotic compounding by IV: Dispensing robot vs. manual compounding in biological safety cabinet by Hao ML, Wang T, Zhu JQ, Song YJ, Gong TJ, Zou LK, Liu J and Yan JF in Journal of Oncology Pharmacy Practice
Additional file 1 of Machine learning based study for the classification of Type 2 diabetes mellitus subtypes
Creators: name: Ordoñez-Guillen, Nelson E.
name: Gonzalez-Compean, Jose Luis
name: Lopez-Arevalo, Ivan
name: Contreras-Murillo, Miguel
name: Aldana-Bobadilla, Edwin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 1.
Fatal dengue hemorrhagic fever imported into Germany
Creators: name: Schmidt-Chanasit, Jonas
name: Tenner-Racz, K.
name: Poppert, D.
name: Emmerich, Petra
name: Frank, Christina
name: Dinges, C.
name: Penning, R.
name: Nerlich, A.
name: Racz, Paul
name: Günther, Stephan
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2011
Subjects: subject: Dengue virus
subject: Germany
subject: Dengue hemorrhagic fever
subject: Immunohistochemistry
subject: 610 Medizin

description: Dengue virus (DENV) is an arthropod-borne virus (family Flaviviridae) causing dengue fever or dengue hemorrhagic fever. Here, we report the first fatal DENV infection imported into Germany. A female traveler was hospitalized with fever and abdominal pain after returning from Ecuador. Due to a suspected acute acalculous cholecystitis, cholecystectomy was performed. After cholecystectomy, severe spontaneous bleeding from the abdominal wound occurred and the patient died. Postmortem analysis of transudate and tissue demonstrated a DENV secondary infection of the patient and a gallbladder wall thickening (GBWT) due to an extensive edema.
sj-pdf-1-prx-10.1177_00332941211027320 - Supplemental material for When and How Job Design Influences Work Motivation: A Self-Determination Theory Approach
Creators: name: Liu, YuXin
name: Wang, Shuai
name: Zhang, Jianwei
name: Li, ShuJie
Publisher: name: SAGE Journals
Year: 2021
Subjects: Psychology not elsewhere classified

description: Supplemental material, sj-pdf-1-prx-10.1177_00332941211027320 for When and How Job Design Influences Work Motivation: A Self-Determination Theory Approach by YuXin Liu, Shuai Wang, Jianwei Zhang and ShuJie Li in Psychological Reports
Neue Arbeitsfelder in der Bibliothek des Robert Koch-Instituts: Open Access und institutionelles Repositorium
Creators: name: Senst, Henriette
name: Erling, Jens
Publisher: name: Robert Koch-Institut
Year: 2012
Subjects: subject: Robert Koch-Institut
subject: Bibliothek
subject: institutionelles Repositorium
subject: Publikationsprozess
subject: Wissenschaftler
subject: Autoren-Verlags-Vertrag
subject: Robert Koch-Institute
subject: library
subject: institutional repository
subject: publication process
subject: scientists
subject: copyright transfer agreement
subject: 610 Medizin

description: Die Bibliothek des Robert Koch-Instituts (RKI) existiert seit der Gründung des Instituts für Infektionskrankheiten im Jahr 1891. Bis in die 1990iger Jahre bestand die Bibliotheksarbeit aus dem klassischen Dreiklang Erwerben – Erschließen – Bereitstellen (von Print-Medien). Die IT hat nicht nur dramatisch das Arbeitsverhalten und die Forschungsmöglichkeiten der Wissenschaftler verändert, sondern auch massiv zur Verlagerung von Arbeitsschwerpunkten in der Bibliothek geführt. Zwei neue Arbeitsgebiete werden im Folgenden vorgestellt: Der Betrieb eines Publikationsservers und die Betreuung der RKI-Wissenschaftler während des Publikationsprozesses eigener Veröffentlichungen.
description: The Robert Koch-Institute’s Library exists since foundation of the Institute for Infectious Diseases in 1891. Until the nineties of the last century acquisition, indexing and allocation (of print media) where the three typical tasks of the library. The progression of IT did not only change the work habits and research possibilities of the scientists dramatically; it also led to a massive shift in the tasks of the library. Two new areas of work, which cannot be assigned to classical library tasks, will be introduced below: The operation of an institutional repository and the support of scientists during the publication process.
Modeling low- and high-frequency noise in transmon qubits with resource-efficient measurement
Creators: name: Tripathi, Vinay
name: Chen, Huo
name: Levenson-Falk, Eli
name: Lidar, Daniel A.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Transmon qubits experience open system effects that manifest as noise at a broad range of frequencies. We present a model of these effects using the Redfield master equation with a hybrid bath consisting of low and high-frequency components. We use two-level fluctuators to simulate 1/f-like noise behavior, which is a dominant source of decoherence for superconducting qubits. By measuring quantum state fidelity under free evolution with and without dynamical decoupling (DD), we can fit the low- and high-frequency noise parameters in our model. We train and test our model using experiments on quantum devices available through IBM quantum experience. Our model accurately predicts the fidelity decay of random initial states, including the effect of DD pulse sequences. We compare our model with two simpler models and confirm the importance of including both high-frequency and 1/f noise in order to accurately predict transmon behavior.
description: 17 pages, 9 figures
Microsomal triglyceride transfer protein -164 T > C gene polymorphism and risk of cardiovascular disease: results from the EPIC-Potsdam case-cohort study
Creators: name: Giuseppe, Romina Di
name: Pechlivanis, Sonali
name: Fisher, Eva
name: Arregui, Maria
name: Weikert, Beate
name: Knüppel, Sven
name: Buijsse, Brian
name: Fritsche, Andreas
name: Willich, Stefan N.
name: Joost, Hans-Georg
name: Boeing, Heiner
name: Moebus, Susanne
name: Weikert, Cornelia
Publisher: name: Robert Koch-Institut
Year: 2013
Subjects: subject: Myocardial infarction
subject: Genetics
subject: FOS: Biological sciences
subject: Epidemiology
subject: Cholesterol
subject: Ischemic stroke
subject: Additive interaction
subject: 610 Medizin

description: Background: The microsomal triglyceride transfer protein (MTTP) is encoded by the MTTP gene that is regulated by cholesterol in humans. Previous studies investigating the effect of MTTP on ischemic heart disease have produced inconsistent results. Therefore, we have tested the hypothesis that the rare allele of the -164T > C polymorphism in MTTP alters the risk of cardiovascular disease (CVD), depending on the cholesterol levels. Methods: The -164T > C polymorphism was genotyped in a case-cohort study (193 incident myocardial infarction (MI) and 131 incident ischemic stroke (IS) cases and 1 978 non-cases) nested within the European Prospective Investigation into Cancer and Nutrition (EPIC)–Potsdam study, comprising 27 548 middle-aged subjects. The Heinz Nixdorf Recall study (30 CVD cases and 1 188 controls) was used to replicate our findings. Results: Genotype frequencies were not different between CVD and CVD free subjects (P = 0.79). We observed an interaction between the -164T > C polymorphism and total cholesterol levels in relation to future CVD. Corresponding stratified analyses showed a significant increased risk of CVD (HRadditve = 1.38, 95% CI: 1.07 to 1.78) for individuals with cholesterol levels C functional polymorphism with total cholesterol levels. Thereby risk allele carriers with low cholesterol levels may be predisposed to an increased risk of developing CVD, which seems to be abolished among risk allele carriers with high cholesterol levels.
Acute Jaundice Syndrome community outbreak due to Hepatitis E virus in Am Timan, September 2016 to January 2017
Creators: name: Spina, Alexander
name: Spencer, Craig
name: Beversluis, David
name: Djibrine Mahamatahmat
name: Irwin, Andrea
name: Vernier, Larissa
name: Jong, Maria De
name: Abdoulaye Mahamat Saleh
name: Adoum Assileck Abakar
name: Noh Moussa
name: Ngomtiga Ferdinand
name: Al-Hassana Hassan-Breme
name: Lapeube Timothée
name: Marioma Abdel-Aziz
name: Abba, Mariam Al-Hadj
name: Abakar Mahamat Adam
name: Al-Hissein Issa Mahamat Nour
name: Hogema, Boris
name: Alfani, Prince
name: White, Kate
name: Kamau, Charity
name: Sang, Sibylle
name: Lenglet, Annick
Publisher: name: F1000Research
Year: 2017

description: MSF initiated an outbreak response in response to active acute jaundice syndrome (AJS) case findings as well as water chlorination, mass distribution of hygiene kits and social mobilisation. This poster describes the outbreak in terms of epidemiological and clinical characteristics, in order to estimate the magnitude and implement control measures.
GHQ: Grouped Hybrid Q Learning for Heterogeneous Cooperative Multi-agent Reinforcement Learning
Creators: name: Yu, Xiaoyang
name: Lin, Youfang
name: Wang, Xiangsen
name: Han, Sheng
name: Lv, Kai
Publisher: name: arXiv
Year: 2023
Subjects: subject: Multiagent Systems (cs.MA)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Previous deep multi-agent reinforcement learning (MARL) algorithms have achieved impressive results, typically in homogeneous scenarios. However, heterogeneous scenarios are also very common and usually harder to solve. In this paper, we mainly discuss cooperative heterogeneous MARL problems in Starcraft Multi-Agent Challenges (SMAC) environment. We firstly define and describe the heterogeneous problems in SMAC. In order to comprehensively reveal and study the problem, we make new maps added to the original SMAC maps. We find that baseline algorithms fail to perform well in those heterogeneous maps. To address this issue, we propose the Grouped Individual-Global-Max Consistency (GIGM) and a novel MARL algorithm, Grouped Hybrid Q Learning (GHQ). GHQ separates agents into several groups and keeps individual parameters for each group, along with a novel hybrid structure for factorization. To enhance coordination between groups, we maximize the Inter-group Mutual Information (IGMI) between groups' trajectories. Experiments on original and new heterogeneous maps show the fabulous performance of GHQ compared to other state-of-the-art algorithms.
The burden of cholera among young children at the MSF CTC in Bentiu PoC, South Sudan
Creators: name: Malaeb, Rami
name: Martins Dada
name: Almeida, Patrick
name: Bhargavi Rao
name: Siddiqui, Ruby
Publisher: name: F1000Research
Year: 2017

description: Bentiu protection of civilians (PoC) camps was set up by the UN mission in South Sudan in 2013 to protect civilians at risk being targeted by warring parties. MSF helps provide secondary health care and activities related to water, sanitation and hygiene promotion and have also opened a cholera treatment centre. This poster describes the results and conclusions drawn from a descriptive analysis performed on the surveillance data recorded at the cholera treatment centre.