cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Ο ρόλος των πανεπιστημίων στην ερευνητική δραστηριότητα. Η ελληνική περίπτωση
Creators: name: Γιουβανοπούλου, Κωνσταντίνα
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2021
Subjects: subject: Έρευνα και ανάπτυξη
subject: Πανεπιστήμιο
subject: Ερευνητική δραστηριότητα
subject: Τριπλή έλικα
subject: Τρίγωνο γνώσης
subject: Σύμπραξη πανεπιστημίων - επιχειρήσεων

description: Η ερευνητική δραστηριότητα των πανεπιστημιακών ιδρυμάτων αποτελεί ένα άκρως ενδιαφέρον πεδίο μελέτης, διότι όπως υποστηρίζεται εκτενώς, σε διεθνές επίπεδο, η συμβολή του στην προαγωγή των εθνικών συστημάτων έρευνας είναι καίριας σημασίας. Η θεωρία της Τριπλής Έλικας που προωθεί τη συνεργασία μεταξύ του κράτους, των Πανεπιστημίων και της βιομηχανίας στηρίζει τη δυναμική της στα θετικά αποτελέσματα που προκύπτουν από τον μετασχηματισμό των ΑΕΙ σε κοιτίδες παραγωγής νέας γνώσης και καινοτομικών προϊόντων και διαδικασιών. Η προοπτική αυτής της σύμπραξης διευρύνει την αποστολή του Πανεπιστημίου, η οποία πλέον υπερβαίνει τον παραδοσιακό ρόλο της έρευνας και της διδασκαλίας και υιοθετεί και την καινοτομία, εξαπλώνοντας το «τρίγωνο της γνώσης». Συνακόλουθα, το Πανεπιστήμιο δύναται να συνεισφέρει ουσιωδώς στην οικονομική ευημερία, όντας προσανατολισμένο στην κατεύθυνση της βιώσιμης ανάπτυξης. Κύριος στόχος της συγκεκριμένης εργασίας είναι η διερεύνηση του ρόλου που διαδραματίζει το ελληνικό Πανεπιστήμιο στο εθνικό σύστημα Έρευνας και Ανάπτυξης. Μέσα από την πραγματολογική ανάλυση ποσοτικών δεδομένων, που βασίζεται στην κατάρτιση διαγραμμάτων και τη μελέτη δεικτών που αποτυπώνουν τις δαπάνες για Ε&Α και τη συνεργατική δυναμική μεταξύ ΑΕΙ και βιομηχανίας και σκιαγραφούν τη συνεισφορά του πανεπιστημιακού ερευνητικού προσωπικού μέσω του αριθμού του, των επιστημονικών του δημοσιεύσεων και την αναγόρευση νέων διδακτόρων, προκύπτει ότι ο ρόλος αυτός καθορίζει σε μεγάλο βαθμό το ελληνικό ερευνητικό σύστημα. Η συγκριτική ανάλυση των δεδομένων που αφορούν την ερευνητική δραστηριότητα των ελληνικών Πανεπιστημίων και την αντίστοιχη των ευρωπαϊκών οδηγεί στο συμπέρασμα ότι στην Ελλάδα τα ακαδημαϊκά ιδρύματα αποτελούν βασικούς φορείς παραγωγής έρευνας, ενώ στα περισσότερα κράτη μέλη της ΕΕ27, παρόλο που ο ρόλος τους είναι σημαντικός, ιδιαίτερο ειδικό βάρος έχει ο τομέας των επιχειρήσεων. Η ανάλυση επικεντρώνεται στη συμβολή του ελληνικού Πανεπιστημίου στο εθνικό σύστημα Έρευνας και Ανάπτυξης σε σχέση με ό,τι σημειώνεται αντιστοίχως στην ΕΕ27 και με δεδομένο τον κομβικό ρόλο του, διαπιστώνεται ότι η θεωρία της Τριπλής Έλικας βρίσκει πρόσφορο έδαφος στην ελληνική περίπτωση.
Physician communication about adolescent vaccination: How is human papillomavirus vaccine different?
Creators: name: Shah, Parth D.
name: Brewer, Noel T.
name: Hall, Megan E.
name: Moss, Jennifer L.
name: Coyne-Beasley, Tamera
name: Gilkey, Melissa B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Low human papillomavirus (HPV) vaccination coverage stands in stark contrast to our success in delivering other adolescent vaccines. To identify opportunities for improving physicians’ recommendations for HPV vaccination, we sought to understand how the communication context surrounding adolescent vaccination varies by vaccine type.
ESSAYS IN MACROECONOMICS
Creators: name: HAWITIBO, ALEMU LAMBAMO
Publisher: name: Universit� degli Studi di Milano
Year: 2020

description: Abstract: Chapter one The aim of this paper is to examine the role of monetary and fiscal policies in explaining macroeconomic fluctuations in Ethiopia using a structural VAR approach, over the period 1997/1998:1 to 2016/17:4. Its mains results can be presented as follows: first, an increase in government spending has an expansionary effect on output, while an increase in tax revenue has a contractionary effect, with spending multipliers larger than net tax revenue multipliers; second, contractionary monetary policy is associated with a fall in output; third, monetary policy contributes to very small fluctuations in output and it is one of the responsible sources of the high and persistence inflation in the country; fourth, the contributions of fiscal policy shocks are larger than that of monetary policy shocks in explaining movements in output, with roughly equivalent contributions coming from shocks in fiscal policy components. Furthermore, the effects of fiscal and monetary policy shocks on output and inflation have improved qualitatively and quantitatively when both policy variables are jointly examined than estimating a separate model; suggesting the role of a joint analysis of fiscal and monetary policy shocks.
Computational and experimental study on silk fibroin and silk fibroin polymer electrolyte for application in transient energy storage devices
Creators: name: Haskew, Mathew
Publisher: name: Lancaster University
Year: 2022

description: Transient implantable medical bionics (TIMBs), such as, degradable and biocompatible batteries that disappear after their operation, are gaining attention because they potentially facilitate the deployment of novel instructive biomaterials for regenerative medicine. In the wider context, the generation of degradable electronics potentially addresses problems associated with electronic waste (E-waste) and these materials can influence biological processes in a controllable manner, (e.g. tissue regeneration and drug delivery via electrical stimulation). Implantable degradable and biocompatible batteries may be capable of satisfying the power requirements of some biomedical devices and then harmlessly degrading.1 Therefore, these batteries are of great interest and a number of different battery designs have been reported in the literature. In this work, Mg and Zn primary air batteries utilising a degradable and biocompatible polymer electrolyte (PE) (silk fibroin [SF] and choline nitrate [Ch]NO3] ionic liquid [IL]) is reported. The batteries detailed in this work offer up to 7.18 Wh L-1 and 3.89 Wh L-1, respectively, which is sufficient to power ultralow power devices (e.g. 10 to 1000 µW pacemakers).5 However, the chemistry that underpins the interactions and performance of the materials utilised in the batteries reported in the literature has yet to be fully explored. Therefore, classical molecular dynamics (MD) simulations have been employed to investigate the interactions between SF and water molecules which are essential to the functionality of the batteries detailed in this work.1 An alanine-glycine (Ala-Gly) crystal model is implemented to represent the SF11, 68 with 7.5 % water by weight, which is analogous to regenerated SF films.1, 116 The silk crystal structure, reported in this work, is in the silk I form (i.e. repeated β-turn type II conformation), because β-sheets are not the predominant secondary structure (ca. 26 %), instead, the 310-helix is the predominant secondary structure (ca. 37 %). Furthermore, the trajectory of water diffusion is reported to be anisotropic (diffusion is prominent along the X-axis of the crystal model) with a diffusivity calculated at 1.60x10-6 cm2 s-1 at 298 K. Similar results were observed for experimentally determined water diffusivity in SF films at 5.79x10-6 cm2 s-1 at 298 K, possessing 36 % β-sheet content. By drawing inspiration from experimental studies on degradable and biocompatible batteries in the literature and producing an appropriate computational model to represent the pertinent materials theoretically (and experimental validation of them), should result in an improved understanding of the science underpinning the interactions and performance of these devices. Thus, a greater control over these devices should be achieved and potentially enable new applications of transient energy storage devices.
Galaxy evolution across the optical emission-line diagnostic diagrams?
Creators: name: Vitale, M.
name: Fuhrmann, L.
name: Garcia-Marin, M.
name: Eckart, A.
name: Zuther, J.
name: Hopkins, A. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The discovery of the M-sigma relation, the local galaxy bimodality, and the link between black-hole and host-galaxy properties, have raised the question whether AGN play a role in galaxy evolution. Several theoretical models implement AGN feedback to explain the observed galaxy luminosity function, and possibly the color and morphological transformation of spiral galaxies into passive ellipticals. To understand the importance of AGN feedback, a study of the AGN populations in the radio-optical domain is crucial. A mass sequence linking star-forming galaxies and AGN has been already noted in previous works, and it is now investigated as possible evolutionary sequence. We observed a sample of 119 intermediate-redshift (0.04
description: 20 pages, 19 figures, accepted for publication in A&A
Molecular chaperones antagonize proteotoxicity by differentially modulating protein aggregation pathways
Creators: name: Summers, Daniel W.
name: Douglas, Peter M.
name: Cyr, Douglas M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: The self-association of misfolded or damaged proteins into ordered amyloid-like aggregates characterizes numerous neurodegenerative disorders. Insoluble amyloid plaques are diagnostic of many disease states. Yet soluble, oligomeric intermediates in the aggregation pathway appear to represent the toxic culprit. Molecular chaperones regulate the fate of misfolded proteins and thereby influence their aggregation state. Chaperones conventionally antagonize aggregation of misfolded, disease proteins and assist in refolding or degradation pathways. Recent work suggests that chaperones may also suppress neurotoxicity by converting toxic, soluble oligomers into benign aggregates. Chaperones can therefore suppress or promote aggregation of disease proteins to ameliorate the proteotoxic accumulation of soluble, assembly intermediates.
Prion propagation by Hsp40 molecular chaperones
Creators: name: Douglas, Peter M.
name: Cyr, Douglas M.
name: Summers, Daniel W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Molecular chaperones regulate essential steps in the propagation of yeast prions. Yeast prions possess domains enriched in glutamines and asparagines that act as templates to drive the assembly of native proteins into beta-sheet-rich, amyloid-like fibrils. Several recent studies highlight a significant and complex function for Hsp40 co-chaperones in propagation of prion elements in yeast. Hsp40 co-chaperones bind non-native polypeptides and transfer these clients to Hsp70s for refolding or degradation. How Hsp40 co-chaperones bind amyloid-like prion conformers that are enriched in hydrophilic residues such as glutamines and asparagines is a significant question in the field. Interestingly, selective recognition of amyloid-like conformers by distinct Hsp40s appears to confer opposing actions on prion assembly. For example, the Type I Hsp40 Ydj1 and Type II Hsp40 Sis1 bind different regions within the prion protein Rnq1 and function respectively to inhibit or promote [RNQ+] prion assembly. Thus, substrate selectivity enables distinct Hsp40s to act at unique steps in prion propagation.
title: The London Madrigal Society and the Role of Antiquarian Societies on the Reception History of Early English Music, 1726–1832
Creators: name: Bassler, Samantha Elizabeth
Publisher: name: The Open University
Year: 2024

description: According to conventional wisdom, there was a lack of interest in early music, and especially English music, during the seventeenth, eighteenth, and nineteenth centuries. This is contrary to the evidence of England’s long history of antiquarianism, which stretches back into the fifteenth century. The focus of this thesis is the history of antiquarianism and its influence on musical tastes in England, and on the history of the ancillary musical tastes of antiquarians as a subset of the English population. The thesis includes an examination of antiquarian societies, specifically musical antiquarian societies, and the importance of antiquarian societies to the club culture of England writ large. The London 
Madrigal Society (LMS), an antiquarian organisation with a large library deposited in the British Library (shelfmark GB-Lms.Mad.Soc.A–D, F–H), is integral to this study, and the thesis includes an examination of its holdings. The Academy of Ancient Music, as the founding organisation to the Madrigal Society, is also significant to this study, due to its shared membership, repertoire, and governance with the LMS. The Madrigal Society’s collection has not yet received sufficient mention by scholars considering English antiquarianism; as an in-depth study of the LMS, this thesis will demonstrate the pivotal role antiquarians played in the preservation of early music in London.
IL DIALETTO DEGLI SHINTE ROSENGRE: ESAME DELLE FONTI E ANALISI DELLA MORFOLOGIA TRA SINCRONIA E DIACRONIA
Creators: name: MELI, GIULIA
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: The discovery of Shinto Rosengro brings about new data to the panorama of old settlement Romani varieties in Italy. Discovered by Leonardo Piasere in the early 90s? and partly published in 2001, the manuscripts witnessing this Neo-Indo-Aryan dialect were arranged from 1892 to 1911. The author, Sigismondo Caccini, was a man who had a strict contact with the community of Shinte Rosengre and took part to its short-range movements through Central Italy. The wide corpus of texts and grammatical descriptions by Caccini consists of six grammars, eighteen tales and four dictionaries counting about four thousand terms. It shows a Sinti variety carrying some peculiar features, which distinguish it from the other old settlement varieties on the Italian ground (Sinti and Abruzzian Romani). This work aims to the description of the morphology of Shinto Rosengro, and to the discussion and possible explanation of some of its peculiarities. It is divided in three main parts. In the first part, a description of the morphology of the word classes of Shinto Rosengro is given (the described classes are: noun, article, adjective, personal pronoun, possessives, demonstratives and verb). Every chapter of this first part is divided into two sections: the first section presents and, if possible, accounts for the forms given by the grammarian Caccini, and shows the evolution of his description; the second section offers a description of the morphology extracted by the texts in Shinto Rosengro, that are considered as the most proximate example of what had to be the actual use of this language. The second part is a collection of five chapters that focus on some peculiar morphological traits of Shinto Rosengro, in order to offer a possible explanation for their genesis. The topics are: the dative/locative syncretism in the noun inflection; the imperfect marker -esta; the periphrastic future built with avra particle; the participle in -men; the abstract derivatives in -ipen/-iben and their distribution. The third part gives a synthetic analysis of some features of Shinto Rosengro, which are presented in relation to the main diagnostic isoglosses proposed by scholars up to now for the classification of Romani dialects. This part focuses especially on the relation of Shinto Rosengro with the geographically nearest old settlement varieties. As a final appendix, the transcription and translation of some unpublished tales of Caccini corpus is proposed.
title: Χλωρίς προϊόντα βιολογικών βοτάνων
title: Chloris organic herbal products
titleType: AlternativeTitle
Creators: name: Γαβαλά, Μαρία
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2022
Subjects: Συσκευασίες
Βιολογικά βότανα
Προϊόντα
Αφίσα
Έντυπο

description: Βασικός σκοπός της παρούσας εργασίας είναι ο σχεδιασμός ενός Brand μιας εταιρείας η οποία θα διαθέτει μία σειρά από βιολογικά προϊόντα, τα οποία θα μπορούν να χρησιμοποιηθούν ως αφεψήματα αλλά και ως βοηθητικά για την υγεία και τον καλλωπισμό του καταναλωτή.
Desmoplakin is Important for Proper Cardiac Cell-Cell Interactions
Creators: name: Borg, Thomas K.
name: McFadden, William A.
name: Bowers, Stephanie L.K.
name: Baudino, Troy A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Normal cardiac function is maintained through dynamic interactions of cardiac cells with each other and with the extracellular matrix. These interactions are important for remodeling during cardiac growth and pathophysiological conditions. However, the precise mechanisms of these interactions remain unclear. In this study we examined the importance of desmoplakin (DSP) in cardiac cell-cell interactions. Cell-cell communication in the heart requires the formation and preservation of cell contacts by cell adhesion junctions called desmosome-like structures. A major protein component of this complex is DSP, which plays a role in linking the cytoskeletal network to the plasma membrane. Our laboratory previously generated a polyclonal antibody (1611) against the detergent soluble fraction of cardiac fibroblast plasma membrane. In attempting to define which proteins 1611 recognizes, we performed two-dimensional electrophoresis and identified DSP as one of the major proteins recognized by 1611. Immunoprecipitation studies demonstrated that 1611 was able to directly pulldown DSP. We also demonstrate that 1611 and anti-DSP antibodies co-localize in whole heart sections. Finally, using a three-dimensional in vitro cell-cell interaction assay, we demonstrate that 1611 can inhibit cell-cell interactions. These data indicate that DSP is an important protein for cell-cell interactions and affects a variety of cellular functions, including cytokine secretion.
American Thoracic Society and National Heart, Lung, and Blood Institute Implementation Research Workshop Report
Creators: name: Thomson, Carey C.
name: Riekert, Kristin A.
name: Szefler, Stanley J.
name: Freemer, Michelle
name: Apter, Andrea
name: Patel, Minal R.
name: Bender, Bruce G.
name: Cloutier, Michelle M.
name: Krishnan, Jerry A.
name: Nguyen, Huong Q.
name: Chambers, David A.
name: Schatz, Michael
name: Weiss, Curtis H.
name: Gerald, Lynn
name: Mularski, Richard A.
name: Wilson, Kevin C.
name: Carson, Shannon S.
name: Wilson, Sandra R.
name: Goss, Christopher H.
name: Okelo, Sande O.
name: Rand, Cynthia S.
name: George, Maureen
name: Gerald, Joe K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: To advance implementation research (IR) in respiratory, sleep, and critical care medicine, the American Thoracic Society and the Division of Lung Diseases from the NHLBI cosponsored an Implementation Research Workshop on May 17, 2014. The goals of IR are to understand the barriers and facilitators of integrating new evidence into healthcare practices and to develop and test strategies that systematically target these factors to accelerate the adoption of evidence-based care. Throughout the workshop, presenters provided examples of IR that focused on the rate of adoption of evidence-based practices, the feasibility and acceptability of interventions to patients and other stakeholders who make healthcare decisions, the fidelity with which practitioners use specific interventions, the effects of specific barriers on the sustainability of an intervention, and the implications of their research to inform policies to improve patients’ access to high-quality care. During the discussions that ensued, investigators’ experience led to recommendations underscoring the importance of identifying and involving key stakeholders throughout the research process, ensuring that those who serve as reviewers understand the tenets of IR, managing staff motivation and turnover, and tackling the challenges of scaling up interventions across multiple settings.
Structure-Guided Prediction of the Functional Impact of DCLK1 Mutations on Tumorigenesis
Creators: name: Carli, Annalisa Leandra Elena
name: Hardy, JM
name: Hoblos, H
name: Ernst, Matthias
name: Lucet, IS
name: Buchert, Michael
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 321101
subject: Cancer cell biology
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 3404
subject: Medicinal and biomolecular chemistry
classificationCode: 3214
subject: Pharmacology and pharmaceutical sciences

description: Doublecortin-like kinase 1 (DCLK1) is a functional serine/threonine (S/T)-kinase and a member of the doublecortin family of proteins which are characterized by their ability to bind to microtubules (MTs). DCLK1 is a proposed cancer driver gene, and its upregulation is associated with poor overall survival in several solid cancer types. However, how DCLK1 associates with MTs and how its kinase function contributes to pro-tumorigenic processes is poorly understood. This review builds on structural models to propose not only the specific functions of the domains but also attempts to predict the impact of individual somatic missense mutations on DCLK1 functions. Somatic missense mutations in DCLK1 are most frequently located within the N-terminal MT binding region and likely impact on the ability of DCLK1 to bind to αβ-tubulin and to polymerize and stabilize MTs. Moreover, the MT binding affinity of DCLK1 is negatively regulated by its auto-phosphorylation, and therefore mutations that affect kinase activity are predicted to indirectly alter MT dynamics. The emerging picture portrays DCLK1 as an MT-associated protein whose interactions with tubulin heterodimers and MTs are tightly controlled processes which, when disrupted, may confer pro-tumorigenic properties.
title: Hybrid composite sensors for improved visual inspection of impact damage
Creators: name: Tabatabaeian, Ali
Publisher: name: University of Glasgow
Year: 2024

description: Advanced visual inspection techniques are essential for ensuring the structural integrity and reliability of laminated fibre reinforced polymer (FRP) composite structures. Given the ever increasing applications of FRP composites in various industries such as aerospace, wind turbine, and automotive, the demand for accurate, efficient, and non-destructive methods to monitor their health becomes paramount. Traditional inspection methods often fall short in detecting defects or damage in composite structures, which can compromise their performance and safety over time. A prime example of this is barely visible impact damage (BVID) caused by out-of-plane loadings such as indentation and low-velocity impact that can considerably reduce the residual strength. Therefore, developing advanced visual inspection techniques is essential for early detection, localisation, and characterisation of defects, thereby enabling proactive maintenance and extending the lifespan of composite structures.

The work in this thesis explores the viability of using hybrid composite sensors for detecting BVID in laminated FRP composite structures. Drawing inspiration from the colour-changing mechanisms found in nature, hybrid composite sensors composed of thin-ply glass and carbon layers are designed and attached to the surface of the laminated FRP composites exposed to out-of-pane loadings. A comprehensive experimental characterisation, including quasi-static indentation and low-velocity impact tests alongside non-destructive evaluations such as ultrasonic C-scan and visual inspection, is conducted to assess the sensor’s efficacy in detecting BVID. After this, a complementary numerical and theoretical study is conducted to optimise the sensor’s design through a parametric study, enabling the evaluation of key design parameters to tailor the sensor for specific applications. This numerical model can serve as a cost-effective and reliable tool for fast parametric design studies. The effectiveness of the sensor is further examined, particularly in automated visual inspection, when employing deep learning-assisted techniques. These deep learning models use images captured from the surfaces of both damaged and intact composites, enabling assessment of the sensors’ potential in enhancing damage pattern recognition and classification. Ultimately, the proposed sensing technology is implemented on curved FRP composite panels, serving as a real-life case study representative of composite gas cylinders. The findings of this research offer insights into the design, characterisation, and application of bio-inspired hybrid composite sensors, thereby enhancing visual inspection capabilities for detecting BVID in composite structures.
Clinical and laboratory findings following transplantation of allogeneic adipose-derived mesenchymal stromal cells in knee osteoarthritis, a brief report
Creators: name: Sadri, Bahareh
name: Tamimi, Atena
name: Nouraein, Shirin
name: Fard, Abolfazl Bagheri
name: Mohammadi, Javad
name: Mohammadpour, Mehdi
name: Hassanzadeh, Mohammad
name: Bajouri, Amir
name: Madani, Hoda
name: Barekat, Maryam
name: Torshizi, Shahedeh Karimi
name: Malek, Mahrooz
name: Liastani, Maede Ghorbani
name: Maal, Alireza Beheshti
name: Niknejadi, Maryam
name: Vosough, Massoud
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Mesenchymal stromal cells (MSCs) injection has been proposed as an innovative treatment for knee osteoarthritis (KOA). Since, allogeneic MSCs can be available as off-the-shelf products, they are preferable in regenerative medicine. Among different sources for MSCs, adipose-derived MSCs (AD-MSCs) appear to be more available. Three patients with KOA were enrolled in this study. A total number of 100 × 106 AD-MSCs was injected intra-articularly, per affected knee. They were followed up for 6 months by the assessment of clinical outcomes, magnetic resonance imaging (MRI), and serum inflammatory biomarkers. The primary outcome of this study was safety and feasibility of allogeneic AD-MSCs injection during the 6 months follow-up. Fortunately, no serious adverse events (SAEs) were reported. Assessment of secondary outcomes of visual analogue scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and knee osteoarthritis outcome score (KOOS) indicated improvement in all patients. Comparison between baseline and endpoint findings of MRI demonstrated a slight improvement in two patients. In addition, decrease in serum cartilage oligomeric matrix protein (COMP) and hyaluronic acid (HA) indicated the possibility of reduced cartilage degeneration. Moreover, quantification of serum interleukin-10 (IL-10) and interleukin-6 (IL-6) levels indicated that the host immune system immunomodulated after infusion of AD-MSCs. Intra-articular injection of AD-MSCs is safe and could be effective in cartilage regeneration in KOA. Preliminary assessment after six-month follow-up suggests the potential efficacy of this intervention which would need to be confirmed in randomized controlled trials on a larger population. This study was registered in the Iranian registry of clinical trials (https://en.irct.ir/trial/46) in 24 April 2018 with identifier IRCT20080728001031N23.
Interpretations of anomalous LHC events with electrons and jets
Creators: name: Dobrescu, Bogdan A.
name: Martin, Adam
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The CMS Collaboration has recently reported some excess events in final states with electrons and jets, in searches for leptoquarks and $W'$ bosons. Although these excesses may be due to some yet-to-be-understood background mismodeling, it is useful to seek realistic interpretations involving new particles that could generate such events. We show that resonant pair production of vector-like leptons that decay to an electron and two jets leads to kinematic distributions consistent with the CMS data.
description: 18 pages, 4 figures; version v2: Eqs. 3.3, 3.5, 3.7 are now written in a U(1)_B invariant way; references added
title: Уголовно-правовая борьба со склонением несовершеннолетних к потреблению наркотических средств или психотропных веществ
Creators: name: ELS IPR BOOKS
Publisher: name: EDP Hub (Идипи Хаб), Ай Пи Ар Медиа
Year: 2024

description: Монография посвящена теоретической разработке проблем уголовно-правовой борьбы со склонением несовершеннолетних к потреблению наркотических средств или психотропных веществ (уголовно-правовое и криминологическое исследование). Автором обосновывается ряд концептуальных научных и практических положений и рекомендаций, направленных на повышение эффективности уголовно-правовых и криминологических исследований в борьбе со склонением несовершеннолетних к потреблению наркотических средств или психотропных веществ. В издании последовательно проанализированы основные проблемы наркотической преступности в современных условиях. Монография адресована, прежде всего, студентам и слушателям юридических образовательных программ, магистрантам, докторантам, научно-педагогическим работникам, преподавателям юридических вузов, а также сотрудникам всех правоохранительных органов. Издание может быть полезно и для широкого круга читателей, интересующихся данным вопросом.
title: Téléphones portables et acteurs du secondaire II : Enquête sur l'utilisation, l'opinion et l'impact du téléphone portable sur les apprentissages scolaires
title: Téléphones portables et acteurs du secondaire II : Enquête sur l'utilisation, l'opinion et l'impact du téléphone portable sur les apprentissages scolaires
titleType: AlternativeTitle
Creators: name: Caminada, Nicolas
name: Grelot, Myriam
Publisher: name: Unknown
Year: 0
Subjects: subject: téléphone portable
subject: gymnase
subject: rupture générationnelle
subject: apprentissages scolaires
subject: devoirs
subject: enseignant.es

description: Principalement conduite au sein du Gymnase de Morges, cette enquête a pour but d’évaluer l’utilisation du téléphone portable par les différents acteurs du secondaire II à des fins d’apprentissage. Elle en documente ainsi l’usage quotidien des gymnasien.es et des enseignant.es et met en avant leur opinion par le biais d’analyse de données quantitatives mais surtout qualitatives obtenues par des sondages transmis au sein du Gymnase. La première partie de ce travail se focalise sur une revue de la littérature au sujet de l’impact des téléphones portables dans le cadre scolaire sur les adolescent.es et leurs apprentissages. Elle établit entre autres la relation très fusionnelle et parfois même de dépendance que les adolescent.es peuvent entretenir avec cet objet. Elle propose également des pistes de réflexion quant à une potentielle fracture générationnelle entre étudiant.es et enseignant.es du Secondaire II dans l’usage du téléphone portable au sein et en dehors de la classe. La deuxième partie du travail est dévolue à l’analyse des réponses obtenues aux deux types de sondages : l’un pour les étudiant.es sur leur relation avec le téléphone portable dans leur travail scolaire et leurs besoins ou envies de l’utiliser davantage au sein de la salle de classe. L’autre questionnaire, pour les enseignant.es, se penche également sur leur relation avec le téléphone portable dans leurs enseignements mais aussi sur leur opinion quant à la place de cet objet dans la vie de leurs élèves. Ce deuxième sondage visait notamment à déceler une potentielle crainte vis-à-vis de l’utilisation du téléphone portable à des fins d’apprentissages. En corrélant les résultats des deux sondages, il en ressort que les élèves et les enseignant.es partagent plus ou moins le même ressenti quant à l’utilisation du téléphone portable en classe, jugé déjà trop envahissant dans la vie quotidienne, c’est-à-dire que l’apport au contenu didactique ne leur semble pour le moment pas justifié. La conclusion reprend ces éléments et suggère de nouvelles pistes de réflexions et d’analyses notamment au sujet de l’utilisation des téléphones portables par les élèves à la maison dans le cadre de leurs devoirs.
Diagnostic Enzymes for Liver Function Test
Creators: name: Lisa Clara
Publisher: name: Zenodo
Year: 2023

description: Liver function tests are vital for the early diagnosis of liver diseases and management of hepatic dysfunction patients. A number of enzymatic reactions were developed to detect the presence of unusual substances that are associated with different types of liver disorders or liver damage. Creative Enzymes' diagnostic enzymes have been used to support the clinical evaluation and research on liver function. Creative Enzymes has been supporting the clinical and research use of liver function evaluation with our diagnostic enzyme products.
title: Interdisciplinarité entre EPS et disciplines scientifiques à l'école : perspectives théoriques et voies adaptées par les enseignants
title: Interdisciplinarité entre EPS et disciplines scientifiques à l'école : perspectives théoriques et voies adaptées par les enseignants
titleType: AlternativeTitle
Creators: name: Guyard, Aurélien
Publisher: name: Unknown
Year: 0
Subjects: subject: Interdisciplinarité
subject: Liens
subject: EPS
subject: Science
subject: Temps
subject: Intérêt

description: Des entretiens semi-directifs ont été menés avec des enseignants d’EPS et de sciences expérimentales (chimie) afin de recueillir puis d’analyser leur conception de l’interdisciplinarité, leur point de vue quant à sa pertinence et à sa place dans les plans d’études. Ces entretiens semi-structurés ont également permis de les interroger à propos de leur expérience éventuelle par rapport à sa mise en œuvre, de les questionner sur les différentes modalités pouvant favoriser cette interdisciplinarité et d’identifier les entraves et obstacles que certains entrevoient. L’analyse du corpus textuel de ces entretiens par le logiciel Alceste a permis de montrer que tous les enseignants interrogés voient un intérêt certain à mettre en place des projets interdisciplinaires afin de répondre à des questions sociétales complexes auxquelles une discipline seule ne pourrait faire face. Malgré tout, tous les enseignants interrogés s’accordent à dire que rien n’est concrètement disponible pour leur donner les moyens de réaliser ces projets interdisciplinaires. Outre le manque de formation concrète à l’interdisciplinarité qui leur permettrait de bien appréhender ces concepts et d’être capables de les intégrer à leurs pratiques, le facteur temps est selon eux le paramètre principal à prendre en compte aujourd’hui pour pouvoir déployer des projets interdisciplinaires et, potentiellement, les réussir. Les enseignants interrogés n’ont pas réalisé de projets interdisciplinaires jusqu’à présent, non pas par manque d’envie ; plutôt par manque d’information pertinente, mais surtout, par manque de temps dans leur agenda et dans celui des élèves. Le sujet reste ouvert pour de futures avancées.
Acyclovir inhibition of Epstein-Barr virus replication.
Creators: name: Colby, B. M.
name: Pagano, J. S.
name: Datta, A. K.
name: Shaw, J. E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1980

description: Acyclovir [9-(2-hydroxyethoxymethyl)guanine] triphosphate inhibits Epstein-Barr virus (EBV)-associated DNA polymerase (DNA nucleotidyltransferase; EC 2.7.7.7) to a greater extent than it inhibits host alpha and beta DNA polymerases. The affinity of the compound for viral polymerase is 100-fold higher than for alpha-polymerase. The extent of inhibition is dependent upon the base composition of the template-primer. The inhibition is prevented by increasing concentrations of deoxyguanosine triphosphate. The EBV-associated DNA polymerase reaction in the presence of the inhibitor, although depressed, proceeds at a linear rate over a long period of time. In contrast, the reaction of Escherichia coli DNA polymerase I in the presence of 2',3'-dideoxythymidine 5'-triphosphate, a DNA chain terminator, levels off after initial linearity. Preincubation of acyclovir triphosphate with DNA and enzyme does not increase its inhibitory activity. The virus-producing cell line P3HRF-1 consistently shows reduced viral genome numbers and viral capsid antigen on prolonged exposure to acyclovir. The number of EBV genomes returns to the control level when the cells are grown in drug-free medium. The results suggest that a competitive mechanism is the major mode of acyclovir inhibition of EBV replication.
An atomic kinetic energy functional with full Weizsacker correction
Creators: name: Acharya, P. K.
name: Parr, R. G.
name: Sears, S. B.
name: Bartolotti, L. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1980

description: A functional is proposed for representing the electronic kinetic energy of the ground state of an N-electron atom or ion in terms of its electron density, T[ρ]=TW[ρ]+T0[ρ]-(C/N1/3)T0[ρ]. Here TW is the Weizsacker quantity (1/8)∫ (∇ ρ · ∇ ρ /ρ)dτ and T0 is the Thomas-Fermi quantity CF∫ ρ 5/3dτ . From Hartree-Fock data on 55 neutral atoms, C=1.412± 0.033; for 1200 atoms and ions, C=1.332± 0.053. The proposed functional gives the derivative δ T/δ ρ its most important correct properties. The term TW is shown to give the kinetic energy of the K shell, whereas the term (C/N1/3)T0 gives an incorrect statistical estimate of that energy. An alternative correction -(C′/N1/3)T gives even better results.
title: Alignment and Reassembly of Broken Specimens for Creep Ductility Measurements
Creators: name: Knauthe, Volker
name: Kraus, Maurice
name: Buelow, Max von
name: Wirth, Tristan
name: Rak, Arne
name: Merth, Laurenz
name: Erbe, Alexander
name: Kontermann, Christian
name: Guthe, Stefan
name: Kuijper, Arjan
name: Fellner, Dieter W.
name: Bender, Jan
name: Botsch, Mario
name: Keim, Daniel A.
Publisher: name: The Eurographics Association
Year: 2024

description: Designing new types of heat-resistant steel components is an important and active research field in material science. It requires detailed knowledge of the inherent steel properties, especially concerning their creep ductility. Highly precise automatic state-of-the-art approaches for such measurements are very expensive and often times invasive. The alternative requires manual work from specialists and is time consuming and unrobust. In this paper, we present a novel approach that uses a photometric scanning system for capturing the geometry of steel specimens, making further measurement extractions possible. In our proposed system, we apply calibration for pan angles that occur during capturing and a robust reassembly for matching two broken specimen pieces to extract the specimen's geometry. We compare our results against µCT scans and found that it deviates by 0.057mm on average distributed over the whole specimen for a small amount of 36 captured images. Additionally, comparisons to manually measured values indicate that our system leads to more robust measurements.
Cellular and subcellular localization of 1,25-(OH)2-vitamin D3 in rat kidney: comparison with localization of parathyroid hormone and estradiol.
Creators: name: Reid, F. A.
name: Sar, M.
name: DeLuca, H. F.
name: Narbaitz, R.
name: Stumpf, W. E.
name: Tanaka, Y.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1980

description: Results of thaw-mount autoradiographic studies of kidney obtained 1--3 hr after a single injection of 1,25-(OH)2-[3H]vitamin D3 to rats showed strong nuclear concentration of radioactivity in podocytes and cells of distal tubules, including the pars convoluta, macula densa, and pars recta. Intermediate nuclear concentration was found in cells of the thin limb of Henle's loops, whereas weak or no nuclear uptake was seen in cells of the proximal tubules. In contrast, after injection of 3H-labeled parathyroid hormone or [3H]estradiol, mainly cells of the proximal tubules were labeled; after 3H-labeled parathyroid hormone, apical cytoplasmic uptake of radioactivity was seen most strongly in the proximal part of the proximal tubules, whereas, after [3H]estradiol, weak nuclear concentration was seen in cells throughout the proximal tubules. The results are consistent with the concept that synthesis of 1,25-(OH)2-vitamin D3 occurs in the proximal tubules under stimulation of parathyroid hormone or estradiol (or other hormones) and that the major site of action of 1,25-(OH)2-vitamin D3 is in the distal tubules.
Oxygen abundances of zCOSMOS galaxies at z~1.4 based on five lines and implications for the fundamental metallicity relation
Creators: name: Maier, C.
name: Lilly, S. J.
name: Ziegler, B. L.
name: team, zCOSMOS
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: A relation between the stellar mass M and the gas-phase metallicity Z of galaxies, the MZR, is observed up to higher redshifts. It is a matter of debate, however, if the SFR is a second parameter in the MZR. To explore this issue at z > 1, we used VLT-SINFONI near-infrared (NIR) spectroscopy of eight zCOSMOS galaxies at 1.3 < z < 1.4 to measure the strengths of four emission lines: Hbeta, [OIII]lambda5007, Halpha, and [NII]lambda6584, additional to [OII]lambda3727 measured from VIMOS. We derive reliable O/H metallicities based on five lines, and also SFRs from extinction corrected Halpha measurements. We find that the MZR of these star-forming galaxies at z~1.4 is lower than the local SDSS MZR by a factor of three to five, a larger change than reported in the literature using [NII]/Halpha-based metallicities from individual and stacked spectra. Correcting N2-based O/Hs using recent results by Newman et al. (2014), also the larger FMOS sample at z~1.4 of Zahid et al. (2014) shows a similar evolution of the MZR like the zCOSMOS objects. These observations seem also in agreement with a non-evolving FMR using the physically motivated formulation of the FMR from Lilly et al. (2013).
description: Proceedings of the IAU symposium 309, Highlight Talk, Vienna, July 2014; based on SINFONI-VLT NIR spectroscopy, run 091.B-0036A
Wastewater Treatment Technology IV WWTT 4P1
Creators: name: Ikudayisi, Akinola
Publisher: name: Walter Sisulu University
Year: 2022
Subjects: Water resources engineering
Civil engineering not elsewhere classified

description: Subject : Wastewater Treatment Technology IV Subject code : WWTT4P1 Qualification : B.Tech Engineering: Civil (Water) Examiners : Dr Akinola Ikudayisi Moderator : Mr Cladious Nhawu Date : June 2019
The ancient heritage of water ice in the solar system
Creators: name: Cleeves, L. Ilsedore
name: Bergin, Edwin A.
name: Alexander, Conel M. O'D.
name: Du, Fujun
name: Graninger, Dawn
name: Öberg, Karin I.
name: Harries, Tim J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Identifying the source of Earth's water is central to understanding the origins of life-fostering environments and to assessing the prevalence of such environments in space. Water throughout the solar system exhibits deuterium-to-hydrogen enrichments, a fossil relic of low-temperature, ion-derived chemistry within either (i) the parent molecular cloud or (ii) the solar nebula protoplanetary disk. Utilizing a comprehensive treatment of disk ionization, we find that ion-driven deuterium pathways are inefficient, curtailing the disk's deuterated water formation and its viability as the sole source for the solar system's water. This finding implies that if the solar system's formation was typical, abundant interstellar ices are available to all nascent planetary systems.
description: 33 pages, 7 figures including main text and supplementary materials. Published in Science
Cellulose biogenesis: Polymerization and crystallization are coupled processes in Acetobacter xylinum
Creators: name: Haigler, C. H.
name: Benziman, M.
name: Brown, R. M.
name: White, A. R.
name: Cooper, K. M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1980

description: Calcofluor White ST, stilbene derivative used commerically as an optical brightener for cellulose, increased the rate of glucose polymerization into cellulose by resting cells of the gram-negative bacterium Acetobacter xylinum. This bacterium normally produces a ribbon of cellulose that is a composite of crystalline microfibrils. In concentrations above 0.1 mM, Calcofluor disrupts the assembly of crystalline cellulose I microfibrils and their integration into a composite ribbon by stoichiometric binding to glucose residues of newly polymerized glucan chains. Under these conditions, the rate of glucose polymerization increases up to 4 times the control rate, whereas oxygen uptake increases only 10-15%. These observed effects are readily reversible. If free Calcofluor is washed away or depleted below the threshold value by binding to cellulose as polymerization continues, ribbon production and the normal rate of polymerization resume. It is concluded that polymerization and crystallization are cell-directed, coupled processes and that the rate of crystallization determines the rate of polymerization. It is suggested that coupling must be maintained for biogenesis of crystalline cellulose I.
Ελληνικές τράπεζες και μη εξυπηρετούμενα δάνεια: στρατηγική και ποιότητα
Creators: name: Παπαχριστοδούλου, Ιωάννης
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2021
Subjects: subject: Τράπεζες
subject: Οικονομία
subject: Στρατηγική
subject: Ποιότητα
subject: Τιτλοποίηση
subject: Μη εξυπηρετούμενα δάνεια

description: Σκοπός της παρούσας εργασίας είναι η αποτύπωση και η μελέτη όλων των προσδιοριστικών παραγόντων των μη εξυπηρετούμενων ανοιγμάτων, καθώς και η μελέτη της σωρευτικής επίλυσης του προβλήματος αυτού μέσω της στρατηγικής επιλογής των τιτλοποιήσεων. Τα μη εξυπηρετούμενα ανοίγματα αποτελούν ένα φαινόμενο που έχει μεγάλη επιρροή σε πολλούς τομείς μιας κοινωνίας, γεγονός που καθιστά την επίλυσή του ως ζήτημα μείζονος σημασίας. Το πρόβλημα των κόκκινων δανείων, όπως αλλιώς ονομάζονται τα μη εξυπηρετούμενα δάνεια, δεν είναι ελληνικό φαινόμενο, καθώς ιδιαίτερα την προηγούμενη δεκαετία απασχόλησε πάρα πολλές χώρες ανά τον κόσμο, ενώ δεν είναι λίγες οι χώρες εκείνες που ταλαιπωρούνται από τα μη εξυπηρετούμενα δάνεια ακόμη και σήμερα. Στην παρούσα εργασία παρουσιάζονται αρχικά ορισμένες έννοιες και τεχνικές τόσο της στρατηγικής όσο και του στρατηγικού management, με ιδιαίτερες αναφορές στον τραπεζικό κλάδο. Εν συνεχεία, γίνεται μια ιστορική αναδρομή στην περίοδο της παγκόσμιας χρηματοοικονομικής κρίσης που ξέσπασε στις ΗΠΑ το 2008, παρουσιάζοντας ορισμένα από τα αίτιά της. Αμέσως μετά, γίνεται αναφορά για την κρίση στις Ευρωπαϊκές χώρες, με ιδιαίτερη μνεία στην Ελλάδα. Τη σκυτάλη στη συνέχεια παίρνουν τα μη εξυπηρετούμενα δάνεια, τα οποία αποτελούν και το κύριο αντικείμενο διαπραγμάτευσης της παρούσας εργασίας. Αρχικά, γίνεται μια ιστορική αναδρομή στα αίτια της γέννησης των κόκκινων δανείων στην Ελλάδα, τα οποία εντοπίζονται αρκετά χρόνια πριν το ξέσπασμα της κρίσης στη χώρα. Στη συνέχεια παρουσιάζεται η διόγκωσή τους κατά τη διάρκεια της κρίσης και το γενικότερο κλίμα απαισιοδοξίας που επικρατούσε την εποχή εκείνη, ενώ η αυλαία πέφτει με την παρουσίαση της στρατηγικής επιλογής των τιτλοποιήσεων, ως του πλέον ενδεδειγμένου τρόπου αντιμετώπισής τους, κρίνοντας από το αποτέλεσμα. Έπειτα, ακολουθεί μια πλήρης αναλυτική αποτύπωση όλων των τιτλοποιήσεων που έχουν πραγματοποιηθεί στην Ελλάδα, μέχρι και τον Οκτώβριο του 2021. Τέλος, παρουσιάζεται η στρατηγική ανάλυση μίας εκ των τεσσάρων συστημικών τραπεζών. Τα κυριότερα συμπεράσματα που προκύπτουν από την παρούσα εργασία, είναι αφενός πως οι τιτλοποιήσεις έδωσαν την ευκαιρία στις ελληνικές τράπεζες να πάρουν βαθιά ανάσα και να ξεφορτωθούν έναν πολύ μεγάλο όγκο κόκκινων δανείων από τους ισολογισμούς τους, και αφετέρου πως η στρατηγική και η ποιότητα στη σύγχρονη εποχή διαδραματίζουν καθοριστικό ρόλο τόσο στην επιβίωση όσο και στην ανάπτυξη των τραπεζών.