cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Stochastic analysis of bistability in coherent mixed feedback loops combining transcriptional and post-transcriptional regulations
Creators: name: Nitzan, Mor
name: Shimoni, Yishai
name: Rosolio, Oded
name: Margalit, Hanah
name: Biham, Ofer
Publisher: name: arXiv
Year: 2014
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Mixed feedback loops combining transcriptional and post-transcriptional regulations are common in cellular regulatory networks. They consist of two genes, encoding a transcription factor and a small non-coding RNA (sRNA), which mutually regulate each other's expression. We present a theoretical and numerical study of coherent mixed feedback loops of this type, in which both regulations are negative. Under suitable conditions, these feedback loops are expected to exhibit bistability, namely two stable states, one dominated by the transcriptional repressor and the other dominated by the sRNA. We use deterministic methods based on rate equation models, in order to identify the range of parameters in which bistability takes place. However, the deterministic models do not account for the finite lifetimes of the bistable states and the spontaneous, fluctuation-driven transitions between them. Therefore, we use stochastic methods to calculate the average lifetimes of the two states. It is found that these lifetimes strongly depend on rate coefficients such as the transcription rates of the transcriptional repressor and the sRNA. In particular, we show that the fraction of time the system spends in the sRNA dominated state follows a monotonically decreasing sigmoid function of the transcriptional repressor transcription rate. The biological relevance of these results is discussed in the context of such mixed feedback loops in {\it Escherichia coli}.
(501388) Malcolm Ernest Faithfull
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Cost-Optimal Switching Protection Strategy in Adaptive Networks
Creators: name: Ogura, Masaki
name: Preciado, Victor M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Social and Information Networks (cs.SI)
subject: Optimization and Control (math.OC)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: In this paper, we study a model of network adaptation mechanism to control spreading processes over switching contact networks, called adaptive susceptible-infected-susceptible model. The edges in the network model are randomly removed or added depending on the risk of spread through them. By analyzing the joint evolution of the spreading dynamics "in the network" and the structural dynamics "of the network", we derive conditions on the adaptation law to control the dynamics of the spread in the resulting switching network. In contrast with the results in the literature, we allow the initial topology of the network to be an arbitrary graph. Furthermore, assuming there is a cost associated to switching edges in the network, we propose an optimization framework to find the cost-optimal network adaptation law, i.e., the cost-optimal edge switching probabilities. Under certain conditions on the switching costs, we show that the optimal adaptation law can be found using convex optimization. We illustrate our results with numerical simulations.
Sustainable Education
Creators: name: PRAMILA Thapa
Publisher: name: Zenodo
Year: 2023
Subjects: Sustainable ,Education

description: This will enable you to become resourceful, a change agent, and empower both yourself and others. I emphasize these points because human power is truly magical, so let's harness it and increase our energy to engage in activities such as reusing, reducing, recycling, and effectively managing resources like water, electricity, transportation, food, and the environment. Ultimately, these actions must be interconnected with the human mind, establishing bonds and connections that will help transform society into a safe, secure, happy, and healthy place for future generations.
(501389) Fanny Jane Lee [nee Blizard]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Use of Machine-Learning Software to Categorize Oncotype DX Data
Creators: name: Gomez,Keven
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: This study looked into the utilization of machine-learning software known as the Clinical Annotation Research Kit or CLARK to abstract and structure Oncotype DX testing results, a genomic test result that is often reported in text-heavy unstructured clinic notes, into a format that can be merged with larger structured databases. Oncotype DX testing results were abstracted for all the patients and each were labeled both manually and through CLARK as being low, intermediate, high or no score based on their risk level. The labeling accuracy of CLARK was compared to manual abstraction.
Exploring the Impact of Brief Training on Student Pharmacists’ Naloxone Communication Skills
Creators: name: Jankowski, Kelly
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: It is unknown whether video or written materials are more effective at improving naloxone communication skills among pharmacists. A pilot randomized controlled trial was conducted that randomized student pharmacists (N=31) to receive training about the use of naloxone to reverse opioid overdoses either by video (experimental) or written materials (control). Primary outcomes were change in: (1) perceived barriers to dispensing naloxone, (2) naloxone communication self-efficacy, (3) naloxone knowledge, and (4) naloxone communication. Naloxone communication was assessed via two simulated patient interactions. Two blinded coders used an observation guide to assess students’ naloxone communication. Linear regressions were used to evaluate change in outcomes measures. For the entire sample, naloxone knowledge and self-efficacy to communicate about naloxone increased and barriers to dispensing naloxone decreased (all p-values < 0.001). Additionally, communication skills improved significantly (p < 0.001) for the entire sample. Students were less likely to use the word ‘overdose’ during their post-training simulated patient encounter. In unadjusted analyses, students with video resources reported significantly higher self-efficacy post-training than the control group (p = 0.047). However, analyses that controlled for demographic characteristics and baseline barriers, knowledge, self-efficacy, or communication levels, found that training material type was not a significant predictor of change in any outcome.This pilot study revealed that brief naloxone training can improve students’ knowledge, self-efficacy, and communication. Given the small sample, results are inconclusive regarding impact of training type on outcomes. A larger trial is needed to evaluate different training materials’ effects on student pharmacists’ naloxone communication and knowledge.
Development of a forest carbon and nitrogen model: Pilot application for a Pinus densiflora forest in Central Korea
Creators: name: Hyungsub Kim
name: Seongjun Kim
name: Jongyeol Lee
name: Chang, Hanna
name: Roh, Yujin
name: Jiae An
name: Yowhan Son
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: This study aimed to develop a forest carbon (C) and nitrogen (N) model, known as the Forest Biomass and Dead organic matter Carbon And Nitrogen (FBDCAN), which can be useful under limited input data availability. An N module was designated with three N pools (biomass, dead organic matter, and soil inorganic N) and ten N cycle processes (N deposition, biological N fixation, N mineralization, immobilization, root N uptake, retranslocation, nitrification, N leaching, denitrification, and turnover), and then integrated into an existing forest C model. A pilot application was carried out for a Pinus densiflora forest in Gwangneung Experimental Forests (PGEF), to verify the performance and reliability of the model. The simulated net N mineralization in 2010 (69.91 kg N ha−1 yr−1) was within the observed range in PGEF. Furthermore, the simulated N stock (3.91 Mg N ha−1) based on the FBDCAN model was consistent with the observed N stock (4.13 Mg N ha−1) in PGEF (r2 = 0.96 to 0.99). The newly developed forest C and N model could be used for the estimation of N cycle processes, N stock, and C stock, even in regions where the input data availability is low.
Additional file 2 of Prevalence of microalbuminuria and associated factors among HIV − infected ART naïve patients at Mulago hospital: a cross-sectional study in Uganda
Creators: name: Kiggundu, Thomas
name: Kalyesubula, Robert
name: Andia-Biraro, Irene
name: Gyaviira Makanga
name: Byakika-Kibwika, Pauline
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 2. Informed consent form.
The Significance of Emotions in Decision Making
Creators: name: PRAMILA Thapa
Publisher: name: Zenodo
Year: 2022
Subjects: Emotions ,Decision Making

description: Summary: This article explores the role of emotions in the decision-making process. It discusses various suggestions and findings in this regard, highlighting the influence of specific chemicals in our brain.Summary: This article explores the role of emotions in the decision-making process. It discusses various suggestions and findings in this regard, highlighting the influence of specific chemicals in our brain.
Additional file 1 of Pharmacovigilance and incidence of adverse drug reactions in hospitalized pediatric patients: a mini systematic review
Creators: name: Khan, Zakir
name: Muhammad, Khayal
name: Karatas, Yusuf
name: Cagri Bilen
name: Khan, Farman Ullah
name: Khan, Faiz Ullah
Publisher: name: figshare
Year: 2020
Subjects: Medicine
Pharmacology
Biotechnology
Cancer
Science Policy

description: Additional file 1. Electronic search strategy.
(501390) George Blizard
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
CALCULATION OF THE ECONOMIC EFFECT OF VOLTAGE LEVEL OPTIMIZATION IN ELECTRICAL NETWORKS BY METHODS OF NONLINEAR PROGRAMMING
Creators: name: Veliyeva, T.D.
Publisher: name: Вестник науки
Year: 2023
Subjects: ELECTRICITY QUALITY
ELECTRICAL GRID
VOLTAGE DEVIATION
FREQUENCY
JET POWER
ASYNCHRONOUS MOTOR
POWER LOSS
ELECTRIC RECEIVER

description: The problems of the influence of voltage deviation on the operation of electrical networks and electricity consumers are considered. The influence of the voltage level on the efficiency of the modes of electrical networks, the occurrence of additional energy losses in the network elements and electrical receivers is investigated.
DESTRUCTION AND PRESERVATION OF CULTURAL HERITAGE
Creators: name: Masliakova, A.
Publisher: name: Вестник науки
Year: 2023
Subjects: DESTRUCTION
PRESERVATION
CULTURAL HERITAGE
NATURAL DISASTERS

description: Unfortunately, natural catastrophes, like the recent earthquake in Turkey and Syria, eliminating everything in their path, are not uncommon. And I would like to dedicated this article to the memory of those who died in the earthquake in Turkey and Syria
(501386) Arthur Frederick Faithfull
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
ELECTRICITY LOSSES AND REPORTING METHODS IN THE ELECTRIC NETWORKS OF AZERBAIJAN
Creators: name: Ismayilova, G.G.
name: Javadova, F.N.
Publisher: name: Вестник науки
Year: 2023
Subjects: POWER NETWORKS
POWER LOSSES
EE LOSSES
REPORTING METHODS
ENERGY EFFICIENCY

description: The article discusses the development of research studies conducted in the direction of the analysis of the structure and reporting methods of electric energy (EE) losses in electric networks (EN) of complex electric power systems. A mathematical, algorithmic, and software development evaluation of the Power System EE losses report and economic impacts, key findings, and research guidelines are provided as a result of measures taken to reduce EE losses
title: Climate impacts on transocean dispersal and habitat in gray whales from the Pleistocene to 2100
Creators: name: Alter, S. Elizabeth
name: Meyer, Matthias
name: Post, Klaas
name: Czechowski, Paul
name: Gravlund, Peter
name: Gaines, Cork
name: Rosenbaum, Howard C.
name: Kaschner, Kristin
name: Turvey, Samuel T.
name: van der Plicht, Johannes
name: Shapiro, Beth
name: Hofreiter, Michael
Publisher: name: Universität Potsdam
Year: 2020

description: Arctic animals face dramatic habitat alteration due to ongoing climate change. Understanding how such species have responded to past glacial cycles can help us forecast their response to today's changing climate. Gray whales are among those marine species likely to be strongly affected by Arctic climate change, but a thorough analysis of past climate impacts on this species has been complicated by lack of information about an extinct population in the Atlantic. While little is known about the history of Atlantic gray whales or their relationship to the extant Pacific population, the extirpation of the Atlantic population during historical times has been attributed to whaling. We used a combination of ancient and modern DNA, radiocarbon dating and predictive habitat modelling to better understand the distribution of gray whales during the Pleistocene and Holocene. Our results reveal that dispersal between the Pacific and Atlantic was climate dependent and occurred both during the Pleistocene prior to the last glacial period and the early Holocene immediately following the opening of the Bering Strait. Genetic diversity in the Atlantic declined over an extended interval that predates the period of intensive commercial whaling, indicating this decline may have been precipitated by Holocene climate or other ecological causes. These first genetic data for Atlantic gray whales, particularly when combined with predictive habitat models for the year 2100, suggest that two recent sightings of gray whales in the Atlantic may represent the beginning of the expansion of this species' habitat beyond its currently realized range.
description: Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe, 965
Near real-time astrometry for spacecraft navigation with the VLBA: A demonstration with the Mars Reconnaissance Orbiter and Odyssey
Creators: name: Max-Moerbeck, W.
name: Brisken, W. F.
name: Romney, J. D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We present a demonstration of near real-time spacecraft astrometry with the VLBA. We detect the X-band downlink signal from Mars Reconnaissance Orbiter and Odyssey with the VLBA and transmit the data over the internet for correlation at the VLBA correlator in near real-time. Quasars near Mars in the plane of the sky are used as position references. In the demonstration we were able to obtain initial position measurements within about 15 minutes of the start of the observation. The measured positions differ from the projected ephemerides by a few milliarcseconds, and the repeatability of the measurement is better than 0.3 milliarcseconds as determined from measurements from multiple scans. We demonstrate that robust and repeatable offsets are obtained even when removing half of the antennas. These observations demonstrate the feasibility of astrometry with the VLBA with a low latency and sub-milliarcsecond repeatability.
description: 10 pages, 2 figures and 5 tables. Accepted for publication in PASP
Additional file 1 of Genotypic and environmental factors influence the proximate composition and quality attributes of sweetpotato (Ipomoea batatas L.)
Creators: name: Rosero, Amparo
name: Sierra, Carlos
name: Pastrana, Iván
name: Leiter Granda
name: José-Luis Pérez
name: Remberto Martínez
name: Morelo, Julio
name: Espitia, Laura
name: Araujo, Hernando
name: Paula, Claudia De
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1: Table S1. Mean square values obtained through the variance component analysis for selected quality traits among 20 sweetpotato genotypes at different harvest times.
Influence of Discrete Sources on Detonation Propagation in a Burgers Equation Analog System
Creators: name: Mi, XiaoCheng
name: Higgins, Andrew J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: An analog to the equations of compressible flow that is based on the inviscid Burgers equation is utilized to investigate the effect of spatial discreteness of energy release on the propagation of a detonation wave. While the traditional Chapman-Jouguet (CJ) treatment of a detonation wave assumes that the energy release of the medium is homogeneous through space, the system examined here consists of sources represented by $δ$-functions embedded in an otherwise inert medium. The sources are triggered by the passage of the leading shock wave following a delay that is either of fixed period or randomly generated. The solution for wave propagation through a large array ($10^3$-$10^4$) of sources in one dimension can be constructed without the use of a finite difference approximation by tracking the interaction of sawtooth-profiled waves for which an analytic solution is available. A detonation-like wave results from the interaction of the shock and rarefaction waves generated by the sources. The measurement of the average velocity of the leading shock front for systems of both regular, fixed-period and randomized sources is found to be in close agreement with the velocity of the equivalent CJ detonation in a uniform medium wherein the sources have been spatially homogenized. This result may have implications for the applicability of the CJ criterion to detonations in highly heterogeneous media (e.g., polycrystalline, solid explosives) and unstable detonations with a transient and multidimensional structure (e.g., gaseous detonation waves).
(501387) Francis E[dward] N[oel] Faithfull
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 3 of Outpatient health care utilization and health expenditures of asylum seekers in Halle (Saale), Germany - an analysis of claims data
Creators: name: Niedermaier, Andreas
name: Freiberg, Anna
name: Tiller, Daniel
name: Wienke, Andreas
name: Führer, Amand
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 3. Additional data on prevalences by single diagnoses and diagnosis groups.
Information Theoretic Navigability From Biased Random Walks
Creators: name: Lin, Vanessa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: In this paper, I explore biased random walks between a source and target node on networks embedded in metric spaces. The bias is defined such that walkers tend to go towards neighbors with the smallest distance from the target in the metric space, to imitate the reasoning of people trying to navigate a network. Navigability is then quantified by the amount of information bits required by these random walkers to find a shortest path. From computations on three different random geometric graphs and two different implementations of bias, I find that the distributions of walk lengths are exponential and that the introduction of bias always reduces the rate parameter, resulting in fewer long walks and more short walks. Additionally, I show that different biases have distinct effects on the number of bits needed to find a shortest path.
Hybrid quantum device based on NV centers in diamond nanomechanical resonators plus superconducting waveguide cavities
Creators: name: Li, Peng-Bo
name: Liu, Yong-Chun
name: Gao, S. -Y.
name: Xiang, Ze-Liang
name: Rabl, Peter
name: Xiao, Yun-Feng
name: Li, Fu-Li
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We propose and analyze a hybrid device by integrating a microscale diamond beam with a single built-in nitrogen-vacancy (NV) center spin to a superconducting coplanar waveguide (CPW) cavity. We find that under an ac electric field the quantized motion of the diamond beam can strongly couple to the single cavity photons via dielectric interaction. Together with the strong spin-motion interaction via a large magnetic field gradient, it provides a hybrid quantum device where the dia- mond resonator can strongly couple both to the single microwave cavity photons and to the single NV center spin. This enables coherent information transfer and effective coupling between the NV spin and the CPW cavity via mechanically dark polaritons. This hybrid spin-electromechanical de- vice, with tunable couplings by external fields, offers a realistic platform for implementing quantum information with single NV spins, diamond mechanical resonators, and single microwave photons.
description: Accepted by Phys. Rev. Applied
Additional file 2 of Outpatient health care utilization and health expenditures of asylum seekers in Halle (Saale), Germany - an analysis of claims data
Creators: name: Niedermaier, Andreas
name: Freiberg, Anna
name: Tiller, Daniel
name: Wienke, Andreas
name: Führer, Amand
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 2. Exemplary Kaplan-Meier analysis illustrating the method used in obtaining one-year prevalences.
(501383) Muriel Grace Faithfull
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Novel Technologies for the Evaluation of Sterile Compounding Technique
Creators: name: Cabelka, Colin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Objective
 
Current methods of evaluating sterile compounding technique rely on over-the-shoulder evaluation and subjective judgement of technique. The objective of this project is to develop an objective method of evaluating technique that is effective for education and competency testing. 

Methods 

A literature search and 2 panels of experts developed an objective rubric for evaluating aseptic technique. A collection of cameras was placed inside a laminar airflow hood to evaluate the technique of first-year student-pharmacists using an objective rubric; output from the cameras was used to evaluate technique errors classified as those impacting sterility and not affecting sterility. The objective evaluation results were compared to over-the-shoulder evaluation completed by teaching assistants as part of a sterile compounding class using a paired t-test.

Results

27 students were recruited for this study and footage of 20 students was deemed acceptable for objective evaluation. A significantly higher amount of errors affecting sterility 75 vs. 19 (95% CI [1.88 to 3.72]; p < 0.001) and total errors 92 vs. 37 (95% CI [1.72-3.78]; p < 0.85) were found in the objective evaluation than the over-the-shoulder group. No difference was found between the groups in the evaluation of non-sterile errors 17 vs. 18 (95% CI [-0.59 to 0.49]; p = 0.39).

Conclusion

The objective evaluation method studied in this investigation shows promise in providing improved evaluation and education of sterile compounding technique due to the significantly higher amount of errors found. Though there are significant limitations to the results, the findings from this study question the reliability of standard over-the-shoulder evaluation and introduce new insights into accurately evaluating sterile compounding.
Additional file 4 of Outpatient health care utilization and health expenditures of asylum seekers in Halle (Saale), Germany - an analysis of claims data
Creators: name: Niedermaier, Andreas
name: Freiberg, Anna
name: Tiller, Daniel
name: Wienke, Andreas
name: Führer, Amand
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 4. Additional data on the Top 10 most prescribed single drugs.
Weight posets associated with gradings of simple Lie algebras, Weyl groups, and arrangements of hyperplanes
Creators: name: Panyushev, Dmitri I.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Combinatorics (math.CO)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 06A07, 17B20, 20F55

description: The set of weights of a finite-dimensional representation of a reductive Lie algebra has a natural poset structure ("weight poset"). Studying certain combinatorial problems related to antichains in weight posets, we realised that the best setting is provided by the representations associated with $\mathbb Z$-gradings of simple Lie algebras (arXiv: math.CO 1411.7683). If $\mathfrak g$ is a simple Lie algebra, then a $\mathbb Z$-grading of $\mathfrak g$ induces a $\mathbb Z$-grading of the corresponding root system $Δ$. In this article, we elaborate on a general theory of lower ideals (or antichains) in the corresponding weight posets $Δ(1)$. In particular, we provide a bijection between the lower ideals in $Δ(1)$ and certain elements of the Weyl group of $\mathfrak g$. An inspiring observation is that, to a great extent, the theory of lower ideals in $Δ(1)$ is similar to the theory of upper (= ad-nilpotent) ideals in the whole poset of positive roots $Δ^+$.
description: 19 pages
(501384) Nora Violet Faithfull
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Coarse-graining polymer solutions: a critical appraisal of single- and multi-site models
Creators: name: D'Adamo, Giuseppe
name: Menichetti, Roberto
name: Pelissetto, Andrea
name: Pierleoni, Carlo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We critically discuss and review the general ideas behind single- and multi-site coarse-grained (CG) models as applied to macromolecular solutions in the dilute and semi-dilute regime. We first consider single-site models with zero-density and density-dependent pair potentials. We highlight advantages and limitations of each option in reproducing the thermodynamic behavior and the large-scale structure of the underlying reference model. As a case study we consider solutions of linear homopolymers in a solvent of variable quality. Secondly, we extend the discussion to multi-component systems presenting, as a test case, results for mixtures of colloids and polymers. Specifically, we found the CG model with zero-density potentials to be unable to predict fluid-fluid demixing in a reasonable range of densities for mixtures of colloids and polymers of equal size. For larger colloids, the polymer volume fractions at which phase separation occurs are largely overestimated. CG models with density-dependent potentials are somewhat less accurate than models with zero-density potentials in reproducing the thermodynamics of the system and, although they presents a phase separation, they significantly underestimate the polymer volume fractions along the binodal. Finally, we discuss a general multi-site strategy, which is thermodynamically consistent and fully transferable with the number of sites, and that allows us to overcome most of the limitations discussed for single-site models.
description: 23 pages, 9 figures, 4 tables
A study of the effectiveness of an empowerment-centered approach to sexual health education in Guatemala
Creators: name: Curtis, Regan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Teenage pregnancy and sexually-transmitted infections (STIs) are two major issues affecting public health in Guatemala today, and education provides a potential solution. Though research exists into the various approaches to reproductive health education, few programs have been created specifically for Guatemala. This project used past findings to implement an empowerment-centered approach to education, contextualizing sexual health among other factors like gender identity, socioeconomic status, and race. The eight-week program, called Chicas Unidas, was implemented in a school in rural Santa María de Jesús, Guatemala with female students ages 11 through 16, who completed pre-tests, post-tests, and interviews. 50 local parents and older siblings were also interviewed. This paper analyzes the findings from this research with special attention to intergenerational changes, gender roles, education, and cultural/religious norms. Catholic beliefs, fear of illness, and machismo (sexism) were the main factors that prevented women from using contraception. Chicas Unidas was successful in increasing knowledge levels of puberty, healthy relationships, and reproduction. The ultimate goal of this project is to elevate the voices of the community so future programs can implement effective, culturally-sensitive sexual health curriculum based in community feedback.
Additional file 1 of Outpatient health care utilization and health expenditures of asylum seekers in Halle (Saale), Germany - an analysis of claims data
Creators: name: Niedermaier, Andreas
name: Freiberg, Anna
name: Tiller, Daniel
name: Wienke, Andreas
name: Führer, Amand
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 1. Additional information on the asylum process in Germany.
Science Fiction and the Divine: How Invincible, Watchmen, and Rick and Morty Critique Traditional Notions of the Western Christian God
Creators: name: Blong, Matthew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: This essay will focus its analysis on three contemporary television shows: Invincible, Watchmen, and Rick and Morty. Each of these three shows uses its unique set of narrative structures and vivid characters to reflect critically on traditional religious ideas concerning a personal, creator God, often using sharp satire. First, Invincible follows the up-and-coming superhero Mark Grayson, who is the son of the most powerful man in the world, Omni-Man. Mark Grayson struggles to bring justice to a morally ambiguous world, filled with ironic twists of superhero tropes, a heartening pathos for the human, and a heavy dose of graphic violence. The main conflict in the show arises when Omni-Man’s character is brought into question after the mysterious murder of Earth’s go-to defenders: the Guardians of the Globe. Second, Watchmen, a sequel to the acclaimed 1986 graphic novel, depicts a dystopian America following the events of its original source material. Instead of commenting directly on Reagan’s America, Watchmen focuses its political critique on the rise of white supremacist movements primarily through the perspective of Angela Abar, or Sister Night, who works for the Tulsa, Oklahoma, Police Department as an undercover superhero. But the plots thickens when a narcissistic trillionaire, Lady Trieu, and the white supremacist organization Seventh Kalvary compete to kill Dr. Manhattan and steal his powers. Dr. Manhattan, who after a tragic accident at a government research facility, became an all-powerful superpowered being. Through his atomic powers, this blue Übermensch has the power to alleviate human suffering, but similar to the Deistic God of the Enlightenment, he chooses not to. Third, Rick and Morty funnels its narrative powers into constructing ridiculous yet touching adventures of an alcoholic genius scientist and his fourteen-year-old grandson. Through witty yet (at times) grotesque humor, Rick and Morty deploys a litany of cultural and science fiction references to deconstruct popular notions of faith, reason, and the human purpose.
A New “Age” of Global Climate Governance: The Role of Youth in the UNFCCC Process
Creators: name: Cummings, Jamie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Youth activists such as Greta Thunberg have been fundamental in garnering greater recognition and mobilizing action to address the climate crisis. However, without tangible power via the right to vote in most nations, it is difficult to represent the voice and will of young people. Furthermore, international organizations, which are typically tasked with setting standards for such expansive global challenges, like climate change, face a democratic deficit as delegates sent to participate are not chosen by popular vote. Public interest groups, formally called stakeholders, composed of civilians from various social, demographic, or business entities are intended to bridge this gap and provide greater democratic legitimacy to multilateral institutions. The United Nations and their climate arm, the United Nations Framework Convention on Climate Change (UNFCCC), brings stakeholder groups and international delegations together annually at the Conference of Parties (COP) in order to address the challenges presented by a warming world. Youth and Children are one of these designated UN stakeholder groups that strive to hold parties accountable to upscale their ambitions and engage more democratically with civil society. In this thesis, I seek to clearly establish the growing role that youth play in the UNFCCC process.
Large scale flows in transitional plane Couette flow: a key ingredient of the spot growth mechanism
Creators: name: Couliou, M.
name: Monchaux, R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Using Particle Image Velocimetry (PIV) in a new experimental plane Couette flow, we investigate the dynamics of turbulent patches invading formerly laminar flows. We evidence experimentally for the first time in this geometry the existence of large scale flows. These flows appear as soon as laminar and turbulent domains coexist. Spectral analysis is used to study the dynamical evolution of these large scales as well as that of the small scales associated with turbulence. We show that large-scale flows grow before turbulent spots develop and we point out the crucial role they play in the growth mechanism and possibly also in the emergence of organised patterns.
(501381) ____ ? [Cahusac]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The impact of outsourcing bed-based aged care services on quality of care: A multisite observational study
Creators: name: Thompson, Anne
name: Khalil, Hanan
name: Harding, Katherine
name: Kane, R
name: Taylor, Nicholas
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 4203
subject: Health services and systems
classificationCode: 3801
subject: Applied economics
classificationCode: 4407
subject: Policy and administration

description: Background: Outsourcing health-care services has become popular globally, provided by both profit and non-for-profit organizations with varying degrees of quality. To date, few published studies have evaluated the quality of care in health services using outsourcing. Objective: The purpose of this study was to determine if there were differences in quality of care (effectiveness, safety and patient experience) for a Transition Care Program designed to improve older people's independence and confidence after a hospital stay, when provided within a public health network compared to being outsourced to private facilities. Methods: For clients discharged to a residential Transition Care Program operating across three sites from a large health service network (n = 1546), an audit of medical records was completed. Site 1 remained within the public health service (internally managed), whereas Sites 2 and 3 involved outsourcing to residential aged care facilities. The main outcome measures were discharge destination, length of stay and number of falls. Client demographics were analysed descriptively, and inferential statistics for continuous data and negative binomial regression for event data were used to examine differences between the sites. Results: There were differences in quality of care between the internally and outsourced managed sites. One outsourced site discharged a smaller proportion to rehabilitation (P = 0.003) compared to the other two sites. There were differences in length of stay between the three sites. The length of stay was a mean of 4.8 days less at Site 1 (internally managed) (95% Confidence Interval (CI) 0.5 to 9.1) than Site 2 and 4.6 days less (95% CI 1.2 to 8.1) than Site 3. For those discharged to permanent residential care, the length of stay was 9.4 days less at the internal site than Site 2 (95% CI 3.5 to 15.2) and 7.0 days less than Site 3 (95% CI 1.9 to 12). Additionally, a lower rate of falls was recorded at Site 1 (internally managed) compared to Site 2 (outsourced) (incidence rate ratio = 0.44 (95% CI 0.32 to 0.60), P < 0.001). Conclusion: An internally managed Transition Care Program in a public health network was associated with better quality of care outcomes compared to outsourced services.
Применение комбинированной экстракорпоральной детоксикации у пациентов с тяжелым острым панкреатитом: ретроспективное когортное исследование
Creators: name: Масолитин, Сергей
name: Проценко, Денис
name: Магомедов, Марат
name: Тюрин, Игорь
name: Гришина, Лидмила
name: Яралян, Артур
name: Игнатенко, Ольга
name: Быков, Андрей
name: Калинин, Евгений
Publisher: name: figshare
Year: 2023
Subjects: Traditional, complementary and integrative medicine not elsewhere classified

description: INTRODUCTION. Morbidity and mortality of severe acute pancreatitis (SAP) remains high. The most important direction of therapy is the relief of endotoxicosis. The use of extracorporeal detoxification (ECD) is a is a debatable problem. OBJECTIVES. Improving the results of treatment of patients with TOP, through the use of ECD methods. MATERIAL AND METHODS. The study included 25 patients. Group 1: ECD included 9 patients who used standard therapy with selective hemoperfusion (HP) and continuous veno-venous hemofiltration (CVVHF). Group 2 (control) 16 patients received standard therapy. We performed a comparative analysis of the main clinical and laboratory parameters and treatment outcomes between the groups RESULTS. The use of ECD allowed to reduce the number of leukocytes from 14.9 to 8.6 x109/l by 5 days of therapy in group 1, and from 17.6 to 16.1 x109/l in group 2, respectively. The dynamics of CRP concentration from 1 to 5 days changed from 315.6 to 184.6 mg/ml and 274.2 to 352.9 mg/ml in groups 1 and 2, respectively. The level of PCT concentration on days 1-5 decreased from 4.5 to 2.1 ng/ml and 3.95 to 6.9 ng/ml in groups 1 and 2, respectively. The concentration of IL-6 decreased from 1624.3 to 914.3 in group 1, and increased from 1529.8 to 1861.8 pg/ml in group 2, respectively. The dynamics of pH in group 1 was from 7.14 to 7.4 by the 5th day of therapy and 7.13 to 7.22 in group 2, respectively. SOFA by day 5 in group 1 was 4 points and 11 points in group 2, respectively CONCLUSIONS. The use of HP and CVVHF in complex intensive care is accompanied by a significant regression of markers of endogenous intoxication, resolution of the acid-base state and reduces the severity of organ dysfunction and the risk of adverse outcomes, compared with standard treatment
(501382) Alice Mary Faithfull
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.