title: Ð¦Ð¸ÑÐ¾ÐºÐ¸Ð½Ñ ÐºÑÐ¾Ð²Ð¸ Ð² Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐµ ÑÐºÑÑÑÐ°Ð¿Ð¸ÑÐ°Ð¼Ð¸Ð´Ð½ÑÑ Ð½Ð°ÑÑÑÐµÐ½Ð¸Ð¹
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Blood cytokines in the diagnosis of extrapyramidal disorders
Creators: name: Ð¢ÑÐ°ÐºÑÐ¸ÑÐ¾Ð², ÐÐ¼Ð¸ÑÑÐ¸Ð¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: ÑÑÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½ÑÐ¹ ÑÑÐµÐ¼Ð¾Ñ
Ð±Ð¾Ð»ÐµÐ·Ð½Ñ ÐÐ°ÑÐºÐ¸Ð½ÑÐ¾Ð½Ð°
Ð´Ð¸ÑÑÐµÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½Ð°Ñ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ°
roc-Ð°Ð½Ð°Ð»Ð¸Ð·
Ð»Ð¾Ð³Ð¸ÑÑÐ¸ÑÐµÑÐºÐ°Ñ ÑÐµÐ³ÑÐµÑÑÐ¸Ñ
essential tremor
Parkinson's disease
differential diagnosis
roc-analysis
logistic regression

description: ÐÐ° ÑÐµÐ³Ð¾Ð´Ð½ÑÑÐ½Ð¸Ð¹ Ð´ÐµÐ½Ñ ÑÑÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½ÑÐ¹ ÑÑÐµÐ¼Ð¾Ñ Ð¸ Ð±Ð¾Ð»ÐµÐ·Ð½Ñ ÐÐ°ÑÐºÐ¸Ð½ÑÐ¾Ð½Ð° ÑÐ²Ð»ÑÑÑÑÑ ÑÐ°Ð¼ÑÐ¼Ð¸ ÑÐ°ÑÐ¿ÑÐ¾ÑÑÑÐ°Ð½ÑÐ½Ð½ÑÐ¼Ð¸ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸ÑÐ¼Ð¸ ÑÑÐµÐ´Ð¸ Ð±Ð¾Ð»ÐµÐ·Ð½ÐµÐ¹ Ð½ÐµÑÐ²Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ, ÑÐ¾Ð¿ÑÐ¾Ð²Ð¾Ð¶Ð´Ð°ÑÑÐ¸ÑÑÑ ÑÐ°ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð¾Ð¼ Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ. ÐÑ Ð´Ð¸ÑÑÐµÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½Ð°Ñ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ° Ð½Ð° ÑÐ°Ð½Ð½Ð¸Ñ ÑÑÐ°Ð¿Ð°Ñ Ð·Ð°ÑÑÑÐ´Ð½ÐµÐ½Ð°, Ð¿Ð¾ÑÐºÐ¾Ð»ÑÐºÑ ÐµÐ´Ð¸Ð½ÑÑÐ²ÐµÐ½Ð½ÑÐ¼ ÑÐ¸Ð¼Ð¿ÑÐ¾Ð¼Ð¾Ð¼ Ð² Ð´ÐµÐ±ÑÑÐµ Ð¾Ð±Ð¾Ð¸Ñ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ð¹ Ð·Ð°ÑÐ°ÑÑÑÑ ÑÐ²Ð»ÑÐµÑÑÑ ÑÐ¾Ð»ÑÐºÐ¾ ÑÑÐµÐ¼Ð¾Ñ. ÐÐ´Ð¸Ð½ Ð¸Ð· Ð¿ÑÑÐµÐ¹ ÑÐµÑÐµÐ½Ð¸Ñ Ð´Ð°Ð½Ð½Ð¾Ð¹ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ â Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð² ÐºÐ°ÑÐµÑÑÐ²Ðµ Ð¼Ð¸ÑÐµÐ½ÐµÐ¹ Ð´Ð»Ñ Ð´Ð¸ÑÑÐµÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½Ð¾Ð¹ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ Ð¿ÐµÑÐ¸ÑÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÐ½Ð´Ð¾Ð³ÐµÐ½Ð½ÑÑ Ð±Ð¸Ð¾Ð¼Ð°ÑÐºÐµÑÐ¾Ð², Ð»ÐµÐ³ÐºÐ¾Ð´Ð¾ÑÑÑÐ¿Ð½ÑÑ Ð´Ð»Ñ Ð°Ð½Ð°Ð»Ð¸Ð·Ð°. Ð¢Ð°ÐºÐ¸Ð¼ Ð¾Ð±ÑÐ°Ð·Ð¾Ð¼, ÑÐµÐ»ÑÑ Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð¸Ð»Ð°ÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¼ÐµÑÐ¾Ð´Ð° Ð´Ð¸ÑÑÐµÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½Ð¾Ð¹ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ Ð´ÑÐ¾Ð¶Ð°ÑÐµÐ»ÑÐ½Ð¾Ð¹ ÑÐ¾ÑÐ¼Ñ Ð±Ð¾Ð»ÐµÐ·Ð½Ð¸ ÐÐ°ÑÐºÐ¸Ð½ÑÐ¾Ð½Ð° Ð¸ ÑÑÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½Ð¾Ð³Ð¾ ÑÑÐµÐ¼Ð¾ÑÐ° Ð¿Ð¾ ÑÑÐ¾Ð²Ð½Ñ Ð±Ð¸Ð¾ÑÐ¸Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð² ÐºÑÐ¾Ð²Ð¸.
ÐÐ»Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð±ÑÐ»Ð¾ Ð´Ð¾ÑÑÑÐ¿Ð½Ð¾ Ð¿ÑÑÑ Ð±Ð¸Ð¾ÑÐ¸Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð², Ð¸Ð· ÐºÐ¾ÑÐ¾ÑÑÑ Ð¼ÐµÑÐ¾Ð´Ð¾Ð¼ ROC-Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð¸ Ð»Ð¾Ð³Ð¸ÑÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐµÐ³ÑÐµÑÑÐ¸Ð¸ Ð±ÑÐ»Ð¸ Ð²ÑÑÐ²Ð»ÐµÐ½Ñ Ð´Ð²Ð° ÑÑÐ°ÑÐ¸ÑÑÐ¸ÑÐµÑÐºÐ¸ Ð·Ð½Ð°ÑÐ¸Ð¼ÑÑ â Ð¸Ð½ÑÐµÑÐ»ÐµÐ¹ÐºÐ¸Ð½ 1 Ð¸ Ð¤ÐÐ Ð°Ð»ÑÑÐ°. ÐÐ° Ð¸Ñ Ð¾ÑÐ½Ð¾Ð²Ðµ Ð±ÑÐ»Ð° Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð° Ð¼Ð¾Ð´ÐµÐ»Ñ Ð»Ð¾Ð³Ð¸ÑÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐµÐ³ÑÐµÑÑÐ¸Ð¸, Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÑÑÐ°Ñ Ñ ÑÐ¾ÑÐ½Ð¾ÑÑÑÑ 92.59% Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸ÑÑ Ð´Ð¸ÑÑÐµÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½ÑÑ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÑ ÑÑÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½Ð¾Ð³Ð¾ ÑÑÐµÐ¼Ð¾ÑÐ° Ð¸ Ð´ÑÐ¾Ð¶Ð°ÑÐµÐ»ÑÐ½Ð¾Ð¹ ÑÐ¾ÑÐ¼Ñ Ð±Ð¾Ð»ÐµÐ·Ð½Ð¸ ÐÐ°ÑÐºÐ¸Ð½ÑÐ¾Ð½Ð°.
description: Essential tremor and Parkinsonâs disease are most common movement disorders. They can have overlapping features that makes it difficult to differentiate between the two. The identification of peripherally accessible biomarkers could be possible way to solve the problem.
Five parameters were analyzed and it was found out, that interleukin-1 and TNF-alpha can be used for the differential diagnosis of Parkinsonâs disease and essential tremor.