cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Rebound in epidemic control: How misaligned vaccination timing amplifies infection peaks
Creators: name: Castioni, Piergiorgio
name: Gòmez, Sergio
name: Granell, Clara
name: Arenas, Alex
Publisher: name: arXiv
Year: 2024
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: In this study, we explore the dynamic interplay between the timing of vaccination campaigns and the trajectory of disease spread in a population. Through comprehensive data analysis and modeling, we have uncovered a counter-intuitive phenomenon: initiating a vaccination process at an inopportune moment can paradoxically result in a more pronounced second peak of infections. This "rebound" phenomenon challenges the conventional understanding of vaccination impacts on epidemic dynamics. We provide a detailed examination of how improperly timed vaccination efforts can inadvertently reduce the overall immunity level in a population, considering both natural and vaccine-induced immunity. Our findings reveal that such a decrease in population-wide immunity can lead to a delayed, yet more severe, resurgence of cases. This study not only adds a critical dimension to our understanding of vaccination strategies in controlling pandemics but also underscores the necessity for strategically timed interventions to optimize public health outcomes. Furthermore, we compute which vaccination strategies are optimal for a COVID-19 tailored mathematical model, and find that there are two types of optimal strategies. The first type prioritizes vaccinating early and rapidly to reduce the number of deaths, while the second type acts later and more slowly to reduce the number of cases; both of them target primarily the elderly population. Our results hold significant implications for the formulation of vaccination policies, particularly in the context of rapidly evolving infectious diseases.
description: 18 pages, 7 figures
Torodora arcifera Brachmia
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Torodora
Torodora arcifera

description: 149. Torodora arcifera (Meyrick, 1907: 738) (Brachmia)
Type locality: Bhutan
Distribution: Indian records: South India. Global records: Bhutan.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 73, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Endoscopic vacuum therapy significantly improves clinical outcomes of anastomotic leakages after 2-stage, 3-stage, and transhiatal esophagectomies
Creators: name: Maier, Jonas
name: Kandulski, Arne
name: Donlon, N. E.
name: Werner, Jens M.
name: Mehrl, Alexander
name: Müller, Martina
name: Doenecke, Axel
name: Schlitt, Hans J.
name: Hornung, Matthias
name: Weiss, A. R. R.
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: Endoscopic vacuum therapy · Anastomotic leak · Esophagectomy · Gastric tube reconstruction · Endoscopic vacuum-assisted closure therapy · Negative pressure wound therapy
subject: 610 Medizin

description: Background
Anastomotic leakages after esophagectomies continue to constitute significant morbidity and mortality. Intrathoracic anastomoses pose a high risk for mediastinitis, sepsis, and death, if a leak is not addressed timely and appropriately. However, there are no standardized treatment recommendations or algorithms as for how to treat these leakages.
Methods
The study included all patients at the University Hospital Regensburg, who developed an anastomotic leakage after esophagectomy with gastric pull-up reconstruction from 2007 to 2022. Patients receiving conventional treatment options for an anastomotic leakage (stents, drainage tubes, clips, etc.) were compared to patients receiving endoscopic vacuum-assisted closure (eVAC) therapy as their mainstay of treatment. Treatment failure was defined as cervical esophagostomy formation or death.
Results
In total, 37 patients developed an anastomotic leakage after esophagectomy with a gastric pull-up reconstruction. Twenty patients were included into the non-eVAC cohort, whereas 17 patients were treated with eVAC. Treatment failure was observed in 50% of patients (n = 10) in the non-eVAC cohort and in 6% of patients (n = 1) in the eVAC cohort (p < 0.05). The 90-day mortality in the non-eVAC cohort was 15% (n = 3) compared to 6% (n = 1) in the eVAC cohort. Cervical esophagostomy formation was required in 40% of cases (n = 8) in the non-eVAC cohort, whereas no patient in the eVAC cohort underwent cervical esophagostomy formation.
Conclusion
eVAC therapy for leaking esophagogastric anastomoses appears to be superior to other treatment strategies as it significantly reduces morbidity and mortality. Therefore, we suggest eVAC as an essential component in the treatment algorithm for anastomotic leakages following esophagectomies, especially in patients with intrathoracic anastomoses.
Additional file 1: of Challenges in initiating antiretroviral therapy for all HIV-infected people regardless of CD4 cell count
Creators: name: Bigna, Jean
name: Plottel, Claudia
name: Sinata Koulla-Shiro
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences

description: Multilingual abstracts in the five official working languages of the United Nations. (PDF 305 kb)
Torodora artiasta Brachmia
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Torodora
Torodora artiasta

description: 150. Torodora artiasta (Meyrick, 1911a: 715) (Brachmia)
Type locality: India, Tamil Nadu, Nilgiris
Distribution: Indian records: Tamil Nadu.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 73, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 1: of A method for positive forensic identification of samples from extremely low-coverage sequence data
Creators: name: Vohr, Samuel
name: Najar, Carlos Buen Abad
name: Shapiro, Beth
name: Green, Richard
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: Additional Methods and Results, Additional methods and additional simulation and sequencing results. (PDF 532Â kb)
Impact of PIEZO1‐channel on inflammation and osteoclastogenesis mediated via periodontal ligament fibroblasts during mechanical loading
Creators: name: Schröder, Agnes
name: Neher, Katharina
name: Krenmayr, Bernhard
name: Paddenberg, Eva
name: Spanier, Gerrit
name: Proff, Peter
name: Kirschneck, Christian
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: mechanosensitive electron channels, orthodontic tooth movement, periodontal ligament fibroblasts, PIEZO1
subject: 610 Medizin

description: The identification of mechanosensitive ion channels and their importance in innate immunity provides new starting points to elucidate the molecular mechanisms of orthodontic tooth movement. The mechanosensitive electron channel PIEZO1 (Piezo Type Mechanosensitive Ion Channel Component 1) may play a crucial role in orthodontic tooth movement. To investigate the role of the PIEZO1 channel, periodontal ligament fibroblasts (PDLF) were subsequently treated with a PIEZO1 inhibitor (GsMTx) with simultaneous pressure application or with an activator (JEDI2) without mechanical strain. The expression of genes and proteins involved in orthodontic tooth movement was examined by RT-qPCR, Western blot and ELISA. In addition, the effect on PDLF-mediated osteoclastogenesis was investigated in a coculture model using human monocytes. Inhibition of PIEZO1 under pressure application caused a reduction in RANKL (receptor activator of NF-kB ligand) expression, resulting in decreased osteoclastogenesis. On the other hand, activation of PIEZO1 without mechanical strain downregulated OPG (osteoprotegerin), resulting in increased osteoclastogenesis. PIEZO1 appears to play a role in the induction of inflammatory genes. It was also shown to influence osteoclastogenesis.
Torodora biovalata Wadhawan & Walia 2007
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Torodora
Torodora biovalata

description: 151. Torodora biovalata Wadhawan & Walia, 2007: 212
Type locality: India, Rajasthan, Jharoal
Distribution: Indian records: Haryana, Himachal Pradesh, Punjab, Rajasthan.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 73, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 1:Figure S1. of Development of a SNP-based assay for measuring genetic diversity in the Tasmanian devil insurance population
Creators: name: Wright, Belinda
name: Morris, Katrina
name: Grueber, Catherine
name: Willet, Cali
name: Gooley, Rebecca
name: Hogg, Carolyn
name: OâMeally, Denis
name: Hamede, Rodrigo
name: Jones, Menna
name: Wade, Claire
name: Belov, Katherine
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Cancer

description: Number of reads by sample in trial MiSeq run (blue bars) manually normalising across samples and amplicons using serial dilutions. Red bars indicate reads from Miseq run of samples normalised using the Sequalprep (Invitrogen) plate-based normalisation kit. Nb. Much lower density of reads/sample for those normalised using the Sequalprep kit as many more samples and additional markers included in run however coverage was far more even across samples and markers and averaged at almost 200Ă  per sample. Trial run data was not used for any statistcial analyses. Table S1. Amplicon characteristics and primer details for putatively neutral loci. Table S2. Genomic locations, allele variants, and minor allele frequencies (MAF) for putatively neutral SNPs. Genotype refers to ratio of p2/2pq/q2. Loci showing statistically significant deviation from Hardy-Weinberg equilibrium at Îą = 0.05 are marked with an *. Table S3. Haplotypes and their frequencies for putatively neutral amplicons used in the final genotyping assay. Table S4. Comparison of paternity results for eight offspring genotyped at both microsatellite and SNP markers. Sire predictions which differed between the two genotyping methods are in bold. Table S5. Multiplex conditions for the 12 microsatellite loci genotyped herein. (DOCX 77 kb)
Torodora bracculata Brachmia
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Torodora
Torodora bracculata

description: 152. Torodora bracculata (Meyrick, 1911a: 710) (Brachmia)
Type locality: India, Assam, Khasis [Now in Meghalaya]
Distribution: Indian records: Meghalaya.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 73, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 1: Table S1. of CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL)
Creators: name: Oldenburg, Darby
name: Yuanbin Ru
name: Weinhaus, Benjamin
name: Cash, Steve
name: Theodorescu, Dan
name: Guin, Sunny
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Clinicopathologic characteristics of bladder cancer patient samples in microarray datasets. Figure S1. CD44 and RHAMM expression after 4MU treatment in bladder cancer cells +/− AGL. Figure S2. CD44 and RHAMM expression after HA treatment in bladder cancer cells +/− AGL. Figure S3. CD44 loss and apoptosis in UMUC3 and T24T cells +/− AGL. Figure S4. RHAMM loss and apoptosis in UMUC3 and T24T cells +/− AGL. Figure S5. Effect of CD44 and RHAMM loss on MGHU4 cell apoptosis +/− AGL. Figure S6. Cellular localization of RHAMM in bladder cancer cells +/− AGL. Figure S7. HAS2 expression and HA synthesis by bladder cancer cells with AGL after CD44 and RHAMM loss. Figure S8. Effect of CD44 and RHAMM loss on MGHU4 cell growth +/− AGL. (DOCX 2675 kb)
Torodora carcerata Lecithocera
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Torodora
Torodora carcerata

description: 153. Torodora carcerata (Meyrick, 1923 c: 39) (Lecithocera)
Type locality: India, Assam, Shillong [Now in Meghalaya]
Distribution: Indian records: Meghalaya.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on pages 73-74, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Arbeitsbezogenes sedentäres Verhalten
Creators: name: Nöscher, Paulus
name: Weber, Andrea
name: Leitzmann, Michael
name: Grifka, Joachim
name: Jochem, Carmen
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: Sedentäres Verhalten · Sitzzeit · Arbeitsmedizin · Public Health · Gesundheitsverhalten
subject: 610 Medizin

description: Hintergrund
Sedentäres Verhalten ist mit einem erhöhten Risiko für chronische Krankheiten und einer höheren Gesamtmortalität assoziiert. Arbeitsbezogenes Sitzen hat einen großen Anteil am täglichen sedentären Verhalten, insbesondere bei Büroangestellten.
Ziel der Arbeit
In dieser Studie sollte untersucht werden, wie viel Zeit bei verschiedenen Aufgaben am Arbeitsplatz und beim Pendeln von Verwaltungsangestellten einer Universitätsklinik in Deutschland im Sitzen verbracht wird.
Material und Methoden
Eine fragebogengestützte Querschnittsstudie mit Verwaltungsangestellten des Universitätsklinikums Regensburg wurde durchgeführt, um arbeitsbezogenes sedentäres Verhalten zu untersuchen.
Ergebnisse
Die Studienpopulation bestand aus 159 Teilnehmenden (54,1 % Frauen, 51,6 % älter als 40 Jahre), was einer Antwortquote von 26 % entspricht. Die durchschnittliche tägliche Sitzzeit am Arbeitsplatz betrug im Median 7,0 h (Interquartilsbereich [IQR] 6,0–7,5 h) und fand hauptsächlich bei der Computerarbeit statt (57,3 %). Die mittlere Stehzeit bei der Arbeit betrug im Median 0,8 h (IQR 0,3–1,4 h). Verwaltungsangestellte verbrachten während des Pendelns im Median 0,7 h (IQR 0,3–1,0 h) pro Tag im Sitzen. Die Teilnehmenden waren der Ansicht, dass langes und ununterbrochenes Sitzen negative (69,6 %) oder eher negative (29,7 %) Auswirkungen auf die Gesundheit hat.
Diskussion
Verwaltungspersonal in Krankenhäusern verbringt einen großen Teil der täglichen Arbeitszeit mit sedentärem Verhalten. Maßnahmen, die es ermöglichen, sowohl im Sitzen als auch im Stehen zu arbeiten, können zu einer Verringerung der arbeitsbedingten Sitzzeit führen und damit die Gesundheit am Arbeitsplatz und im weiteren Sinne die öffentliche Gesundheit verbessern.
Torodora chlorobapta Lecithocera
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Torodora
Torodora chlorobapta

description: 154. Torodora chlorobapta (Meyrick, 1931d: 82) (Lecithocera)
Type locality: India, Sikkim, Gangtok
Distribution: Indian records: Sikkim.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 74, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 3: Table S1. of The geographic pattern of Belgian mortality: can socio-economic characteristics explain area differences?
Creators: name: Hemelrijck, Wanda Van
name: Willaert, Didier
name: Gadeyne, Sylvie
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: All-cause Mortality Rate Ratios (MRRs) and 95Â % confidence intervals (CIs) by district controlled for age, before and after adjustment for individual socio-economic position and household position (Belgium, 2001â  2011). (DOCX 118 kb)
Cutting the Scotogenic loop: Adding flavor to Dark Matter
Creators: name: Kumar, Ranjeet
name: Nath, Newton
name: Srivastava, Rahul
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We introduce a framework for hybrid neutrino mass generation, wherein scotogenic dark sector particles, including dark matter, are charged non-trivially under the $A_4$ flavor symmetry. The spontaneous breaking of the $A_4$ group to residual $\mathcal{Z}_2$ subgroup results in the ``cutting" of the radiative loop. As a consequence the neutrinos acquire mass through the hybrid ``scoto-seesaw" mass mechanism, combining aspects of both the tree-level seesaw and one-loop scotogenic mechanisms, with the residual $\mathcal{Z}_2$ subgroup ensuring the stability of the dark matter. The flavor symmetry also leads to several predictions including the normal ordering of neutrino masses and ``generalized $μ-τ$ reflection symmetry" in leptonic mixing. Additionally, it gives testable predictions for neutrinoless double beta decay and a lower limit on the lightest neutrino mass. Finally, $A_4 \to \mathcal{Z}_2$ breaking also leaves its imprint on the dark sector and ties it with the neutrino masses and mixing. The model allows only scalar dark matter, whose mass has a theoretical upper limit of $\lesssim$ 600 GeV, with viable parameter space satisfying all dark matter constraints, available only up to about 80 GeV. Conversely, fermionic dark matter is excluded due to constraints from the neutrino sector. Various aspects of this highly predictive framework can be tested in both current and upcoming neutrino and dark matter experiments.
description: 40 pages, 3 tables, 18 figures, Important discussion of the different representations of lepton doublets under $A_4$ group is added in appendix, matches with published version in JHEP
title: Sprachliche Vereinfachungen in Materialien für die berufliche Bildung – die Perspektive der Lehrkräfte
Creators: name: Ghobeyshi, Askan
name: Olszycka, Carolina
name: Pappert, Sandra
name: Feldmeier Garcia, Alexis
Publisher: name: Universitäts- und Landesbibliothek Darmstadt
Year: 2024

description: In diesem Beitrag werden die Ergebnisse einer empirischen Untersuchung zum Thema sprachliche Vereinfachungen in der beruflichen Bildung vorgestellt. Dazu wurden leitfadengestützte Interviews mit Lehrkräften an Institutionen zur Berufsausbildung durchgeführt und ausgewertet. Die Ergebnisse zeigen u.a., dass die Lehrkräfte sprachliche Vereinfachung zwar als wesentlich für den Lernerfolg Lernender mit (noch) geringen Deutschkenntnissen erachten, aber den Einsatz sprachlicher Vereinfachungen mit Blick auf sprachliche Anforderungen außerhalb des Unterrichts dennoch oft meiden. Die sich daraus ergebenden Konsequen-zen und notwendig erscheinenden Anpassungen werden abschließend diskutiert, wobei auch genormte Prüfverfahren als institutionelle Hürden mit in den Blick genommen werden.
Unexplained visual loss after primary pars-plana-vitrectomy with silicone oil tamponade in fovea-sparing retinal detachment
Creators: name: Barth, T.
name: Helbig, Horst
name: Maerker, David
name: Gamulescu, Maria-Andreea
name: Radeck, Viola
name: Barth, Teresa
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: Silicone oil tamponade, Retinal detachment, Unexplained visual loss, Vitreoretinal surgery
subject: 610 Medizin

description: Background
To investigate the incidence and clinical characteristics of unexplained visual loss in patients with fovea-sparing rhegmatogenous retinal detachment (RRD) during or after silicone oil (SO) tamponade.
Methods
The medical charts of all patients with macula-on RRDs, who underwent pars-plana-vitrectomy (ppV) with SO tamponade were retrospectively assessed regarding unexplained visual loss (UVL) of ≥ 3 Snellen lines and alterations on optical coherence tomography (OCT) during or after SO tamponade. The clinical data analysed included visual acuity, surgical parameters, OCT images, duration of SO tamponade and the time point of visual decline. Cases with re-detachment or secondary causes of visual loss such as SO emulsification, epiretinal membranes or macular edema were excluded.
Results
Over a 15-year-period, 22 cases with macula-on RRD, which had primarily been treated with ppV and SO tamponade, met the inclusion criteria. In most eyes (n = 20; 91%), the RRD was caused by a giant retinal tear (GRT). In 11 of these 22 cases (50%), best-corrected visual acuity (BCVA) had dropped by at least 3 lines for no apparent reason. In these 11 cases, mean preoperative logMAR BCVA was 0.2 (SD 0.13; range 0-0.5), equal to Snellen’s VA of 0.63, and mean postoperative logMAR BCVA 1.0 (SD 0.24; range 0.5–1.3), equal to Snellen’s VA of 0.10. Visual decline occurred about 12 weeks postoperatively (SD 6.2; range 3–20 ) and comprised 8 lines (SD 2.3; range -11 to -4). SO was removed on average 139 (SD 50.0; range 88–271) days after the first ppV. In 9 cases visual decline occurred while the SO was in-situ. In 2 patients, BCVA decline was noted 2 weeks after SO removal. In all eyes, preoperative central foveal thickness (CFT) was 254 μm (SD 24.2), which decreased to 224 μm (SD 29.6) during SO tamponade and increased to 247 μm (SD 29.2) after SO removal, irrespective of the presence of UVL. The mean follow-up time was 20 months (SD 30.6) after SO removal.
Conclusion
UVL after SO tamponade for macula-on RRD is more frequent than expected. The incidence in our case series was 50%. The mechanism of this phenomenon is still unknown. In general, vitreoretinal surgeons should thoroughly question the need for SO tamponade, inform their patients of possible UVL and remove SO as early as possible.
Trial registration
The study was approved by the local ethics committee on 6th of May 2022 (Ethikkommission der Universität Regensburg, Votum 22-2925-104) and was conducted in accordance with the ethical standards of the Declaration of Helsinki.
Additional file 3: Table S3. of Interaction of smoking and obesity susceptibility loci on adolescent BMI: The National Longitudinal Study of Adolescent to Adult Health
Creators: name: Young, Kristin
name: Graff, Misa
name: North, Kari
name: Richardson, Andrea
name: Mohlke, Karen
name: Lange, Leslie
name: Lange, Ethan
name: Harris, Kathleen
name: Gordon-Larsen, Penny
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Results of SNPxSmoking on %MBMI (Interaction), SNP on %MBMI (Main effects), and SNP on smoking in African American adolescents in Add Health. (DOCX 35 kb)
Liposome-based high-throughput and point-of-care assays toward the quick, simple, and sensitive detection of neutralizing antibodies against SARS-CoV-2 in patient sera
Creators: name: Streif, Simon
name: Neckermann, Patrick
name: Spitzenberg, Clemens
name: Weiss, Katharina
name: Hoecherl, Kilian
name: Kulikowski, Kacper
name: Hahner, Sonja
name: Noelting, Christina
name: Einhauser, Sebastian
name: Peterhoff, David
name: Asam, Claudia
name: Wagner, Ralf
name: Baeumner, Antje J.
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: Liposomes · Neutralizing antibodies · Point-of-care diagnostics · High-throughput screening · SARS-CoV-2
subject: 540 Chemie
subject: 610 Medizin

description: The emergence of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) in 2019 caused an increased interest in neutralizing antibody tests to determine the immune status of the population. Standard live-virus-based neutralization assays such as plaque-reduction assays or pseudovirus neutralization tests cannot be adapted to the point-of-care (POC). Accordingly, tests quantifying competitive binding inhibition of the angiotensin-converting enzyme 2 (ACE2) receptor to the receptor-binding domain (RBD) of SARS-CoV-2 by neutralizing antibodies have been developed. Here, we present a new platform using sulforhodamine B encapsulating liposomes decorated with RBD as foundation for the development of both a fluorescent, highly feasible high-throughput (HTS) and a POC-ready neutralizing antibody assay. RBD-conjugated liposomes are incubated with serum and subsequently immobilized in an ACE2-coated plate or mixed with biotinylated ACE2 and used in test strip with streptavidin test line, respectively. Polyclonal neutralizing human antibodies were shown to cause complete binding inhibition, while S309 and CR3022 human monoclonal antibodies only caused partial inhibition, proving the functionality of the assay. Both formats, the HTS and POC assay, were then tested using 20 sera containing varying titers of neutralizing antibodies, and a control panel of sera including prepandemic sera and reconvalescent sera from respiratory infections other than SARS-CoV-2. Both assays correlated well with a standard pseudovirus neutralization test (r = 0.847 for HTS and r = 0.614 for POC format). Furthermore, excellent correlation (r = 0.868) between HTS and POC formats was observed. The flexibility afforded by liposomes as signaling agents using different dyes and sizes can hence be utilized in the future for a broad range of multianalyte neutralizing antibody diagnostics.
Implementation of safe infant sleep recommendations during night-time sleep in the first year of life in a German birth cohort
Creators: name: Gaertner, Vincent D.
name: Malfertheiner, Sara Fill
name: Postpischil, Janina
name: Brandstetter, Susanne
name: Seelbach-Göbel, Birgit
name: Apfelbacher, Christian J.
name: Melter, Michael
name: Kabesch, Michael
name: Ambrosch, Andreas
name: Arndt, Petra A.
name: Baessler, Andrea
name: Berneburg, Mark
name: Böse-O’Reilly, Stephan
name: Brunner, Romuald
name: Buchalla, Wolfgang
name: Franke, André
name: Häusler, Sebastian
name: Heid, Iris M.
name: Heinze, Stefanie
name: Högler, Wolfgang
name: Koller, Michael
name: Leitzmann, Michael
name: Rothfuß, David
name: Rösch, Wolfgang H.
name: Schaub, Bianca
name: Weidinger, Stephan
name: Wellmann, Sven
name: Kerzel, Sebastian
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: 610 Medizin

description: The aim of our study was to assess the extent to which families followed recommendations, issued by the German society for sleep medicine, for the prevention of sudden infant death syndrome (SIDS) during night-time sleep. Analyzing longitudinal data from a birth cohort located at the University Children’s Hospital Regensburg in Bavaria (Germany), we determined data regarding the infant's sleep location, sleep settings and body position, and exposure to environmental factors. Data were collected in a structured interview after birth and by standardized questionnaires at 4 weeks, 6 months, and 1 year of life, respectively. The majority of 1,400 surveyed infants (94% at 4 weeks) were reported to sleep in the parents’ sleeping room during the first months of life. While the most common furniture was a bedside sleeper (used by 48%), we also observed a considerable proportion of families who regularly practiced bed-sharing and, for 16% of infants, the parents’ bed was the default sleeping place. 12% of infants were still put regularly in the prone position. The vast majority (87%) of the infants were breastfed at some timepoint and 17% lived in a household with one or more smokers. Although most parents implemented many SIDS recommendations, our analysis illustrates a considerable gap between recommendations and intentions after birth on the one hand and actual implementation in real life on the other. The number-one deviation from the current SIDS guidelines during night-time sleep was bed-sharing with an adult.
Additional file 1: of An analysis of baseline data from the PROUD study: an open-label randomised trial of pre-exposure prophylaxis
Creators: name: Dolling, David
name: Desai, Monica
name: McOwan, Alan
name: Gilson, Richard
name: Clarke, Amanda
name: Fisher, Martin
name: Schembri, Gabriel
name: Sullivan, Ann
name: Mackie, Nicola
name: Reeves, Iain
name: Mags Portman
name: Saunders, John
name: Fox, Julie
name: Bayley, Jake
name: Brady, Michael
name: Bowman, Christine
name: Lacey, Charles
name: Taylor, Stephen
name: White, David
name: Antonucci, Simone
name: Mitzy Gafos
name: McCormack, Sheena
name: Gill, Owen
name: Dunn, David
name: Nardone, Anthony
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Baseline Sexual Behaviour Questionnaire. (DOC 155 kb)
Additional file 1: Table S1. of Interaction of smoking and obesity susceptibility loci on adolescent BMI: The National Longitudinal Study of Adolescent to Adult Health
Creators: name: Young, Kristin
name: Graff, Misa
name: North, Kari
name: Richardson, Andrea
name: Mohlke, Karen
name: Lange, Leslie
name: Lange, Ethan
name: Harris, Kathleen
name: Gordon-Larsen, Penny
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Two-sample t-test of differences in BMI and %MBMI by smoking status, stratified by ancestry and sex. (DOCX 72 kb)
Torodora corsota Brachmia
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Torodora
Torodora corsota

description: 155. Torodora corsota (Meyrick, 1911a: 712) (Brachmia)
Type locality: India, Assam, Khasis [Now in Meghalaya]
Distribution: Indian records: Meghalaya. Global records: China.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 74, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 8: Table S5. of Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD)
Creators: name: Grassmann, Felix
name: Cantsilieris, Stuart
name: Anja-Sabrina Schulz-Kuhnt
name: White, Stefan
name: Richardson, Andrea
name: Hewitt, Alex
name: Vote, Brendan
name: Schmied, Denise
name: Guymer, Robyn
name: Weber, Bernhard
name: Baird, Paul
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Mean dosages (S.D.) for diploid and tetraploid cases and controls for C4A, C4B and totalC4. (DOCX 14 kb)
Features of the folklore of the Gainin people
Creators: name: Alimbayeva Gulshayan Gabsalyamovna
name: Abdullina Gulfira Rifovna*
Publisher: name: Zenodo
Year: 2024
Subjects: folklore, legend, ritual folklore, game folklore, aphoristic genres, song folklore.

description: Abstract: In both world and domestic science, special attention is paid to the study of the historical and cultural heritage of certain ethnic groups or tribal structures. Conducting research of various types allows scientists to either discover new things about a particular ethnic group, or confirm or refute existing points of view. No less interesting conclusions can be drawn from the results of studying the current state of the cultural and linguistic identity of the Gainin Bashkirs - representatives of the most ancient Bashkir tribe Gaina (gaina), the historical homeland for many of whom is the territory of the modern Bardymsky district of the Perm Territory. Objective. The article is devoted to the analysis of the peculiarities of the folklore of the Gaina Bashkirs of the Bardymsky District of the Perm Territory on the basis of the field materials of the expedition organised in the summer of 2023. The folklore of the Gaina Bashkirs also reveals specific features, both in terms of individual rites («Plaushinya kishch» based on maiden fortune-telling and the custom of serving dumplings made of curd on the basis of colostrum in honour of cow calving) and some elements of traditional Bashkir customs and holidays. At present, rural cultural centres in the district, together with the local administration, are actively working to revive, among the Gaina Bashkirs, the Bashkir national holidays and customs that have faded away to some extent, and to restore lost examples of folk folklore.
Colorectal cancer survivors’ long-term recollections of their illness and therapy up to seven years after enrolment into a randomised controlled clinical trial
Creators: name: Völkel, Vinzenz
name: Steinger, Brunhilde
name: Koller, Michael
name: Klinkhammer-Schalke, Monika
name: Lindberg-Scharf, Patricia
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: Colorectal cancer, Quality of life, Long-term survival, Patient-reported outcomes, Patient-centred care
subject: 610 Medizin

description: Background
As a consequence of effective treatment procedures, the number of long-term survivors of colorectal cancer is ever increasing. Adopting the method of a previous study on breast cancer patients, the goal of the present research was to investigate colorectal cancer patients’ recollections of their illness and treatment experiences up to seven years after they have been enrolled in a randomised controlled clinical trial on the direct improvement of quality of life (RCT DIQOL).
Methods
Colorectal cancer survivors in Bavaria, Germany were mailed a questionnaire on average 78·3 months after the start of their therapy and enrolment into RCT DIQOL. The questionnaire enquired about their worst experience during the colorectal cancer episode, positive aspects of the illness, and any advice they would give to newly diagnosed patients. Patient responses were categorised by two independent raters and cross-checked by a third independent rater. Frequencies of these categories were then quantitatively analysed using descriptive statistics.
Results
Of 146 remaining survivors initially enrolled in RCT DIQOL, 96 (66%) returned the questionnaire. The majority (33%) of statements regarding the worst experience was referring to “psychological distress”, followed by “indigestion and discomfort during defecation” (17%), and “cancer diagnosis” (16%). Among survivors with history of a stoma, the majority (36%) regarded “stoma” as their worst experience. With 45%, “change in life priorities” has been the most frequent positive category before “support by physicians/ nurses” (25%). 43% of the survivors deemed “fighting spirit” as most important advice to overcome the disease.
Conclusion
Even after many years, colorectal cancer survivors clearly remember experiences from the time of their illness. Echoing the results of the previous breast cancer survivors’ study, “psychological distress”, “change in life priorities” and “fighting spirit” emerged as prominent concepts. In addition, some aspects like the impact of a stoma are of specific importance for colorectal cancer survivors. These findings can be used to inform programmes to improve patient- and quality of life centred aftercare of tumour patients.
Clinical trial information

NCT04930016, date of registration 18.06.2021.
Additional file 1: of Longitudinal survey of Clostridium difficile presence and gut microbiota composition in a Belgian nursing home
Creators: name: Rodriguez, Cristina
name: Taminiau, Bernard
name: Korsak, Nicolas
name: VĂŠronique Avesani
name: Broeck, Johan Van
name: Brach, Philippe
name: DelmĂŠe, Michel
name: Daube, Georges
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Quality analysis of the 16S rRNA gene analysis for the 118 human faecal samples. (DOCX 40Â kb)
Long-term (≥ 15 years) outcome quality after Class II:1 bionator or Herbst multibracket appliance treatment
Creators: name: Bock, Niko Christian
name: Jungbauer, Rebecca
name: Rudzki, Ingrid
name: Proff, Peter
name: Ruf, Sabine
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: Long-term stability · Functional treatment · Peer Assessment Rating index · Overjet · Occlusal relationship
subject: 610 Medizin

description: Purpose
To compare the long-term outcome quality (≥ 15 years) of Class II:1 treatment using either a bionator (BIO) or a Herbst–multibracket appliance (HMB).
Methods
Patients who underwent functional treatment during the ideal treatment period for the respective approach (prepuberty vs. peak/postpeak) were assessed. Inclusion criteria were overjet ≥ 4 mm, skeletal Class II and availability of study casts from before, after and ≥ 15 years after treatment. The study casts were assessed using the Peer Assessment Rating (PAR) index and standard orthodontic cast measurements.
Results
During treatment, PAR score, overjet and sagittal occlusal relationship improved significantly in all groups. Long-term, there was a significant increase of incisor irregularity in the upper (HMB) and lower (BIO) arch and a significant decrease of lower arch width 3 – 3 (BIO). PAR score, overjet, and sagittal occlusal relationship remained stable long-term. Intergroup comparisons revealed significant differences between the BIO and HMB groups in terms of lower arch width (6 – 6), upper and lower arch width (3 + 3/3 – 3) as well as sagittal molar relationship.
Conclusions
The achieved improvement in PAR score, overjet, and sagittal occlusion remained comparably stable long-term in all groups. The long-term changes are probably a consequence of natural aging.
Torodora deltospila Lecithocera
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Torodora
Torodora deltospila

description: 156. Torodora deltospila (Meyrick, 1911a: 706) (Lecithocera)
Type locality: India, Assam, Khasi Hills [Now in Meghalaya]
Distribution: Indian records: Himachal Pradesh, Jammu and Kashmir, Meghalaya, Uttarakhand.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 74, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Uncommon magnetic ordering in the quantum magnet Yb$_{3}$Ga$_{5}$O$_{12}$
Creators: name: Raymond, S.
name: Lhotel, E.
name: Riordan, E.
name: Ressouche, E.
name: Beauvois, K.
name: Marin, C.
name: Zhitomirsky, M. E.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The antiferromagnetic structure of Yb$_{3}$Ga$_{5}$O$_{12}$ is identified by neutron diffraction experiments below the previously-known transition at $T_λ=54$ mK. The magnetic propagation vector is found to be ${\bf k}=(1/2, 1/2, 0)$, an unusual wave-vector in the garnet structure. The associated complex magnetic structure highlights the role of exchange interactions in a nearly isotropic system dominated by dipolar interactions and finds echos with exotic structures theoretically proposed. Reduced values of the ordered moments may indicate significant quantum fluctuations in this effective spin-1/2 geometrically frustrated magnet.
Additional file 5: Table S4. of Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD)
Creators: name: Grassmann, Felix
name: Cantsilieris, Stuart
name: Anja-Sabrina Schulz-Kuhnt
name: White, Stefan
name: Richardson, Andrea
name: Hewitt, Alex
name: Vote, Brendan
name: Schmied, Denise
name: Guymer, Robyn
name: Weber, Bernhard
name: Baird, Paul
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Sensitivity analysis for C4A copy number association. (DOCX 17 kb)
Lepidocyrtus Bourlet 1839
Creators: name: Bellini, Bruno C.
name: Cipola, Nikolas G.
name: Godeiro, Nerivânia N.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Collembola
Entomobryidae
Lepidocyrtus

description: Genus Lepidocyrtus Bourlet, 1839
Diagnosis of Lepidocyrtus s. l. Body covered with rounded or truncate finely striate scales, antennae with four segments, 8+8 eyes, oral cone normal, not elongate, few dorsal body macrochaetae beyond mesothoracic collar, mesonotum well-developed, sometimes projecting head downwards, Abd. IV enlarged, more than 2.5 times the length of Abd. III, furca scaled ventrally, without spines, mucro with two teeth and a basal spine (adapted from Mari Mutt 1976, 1986, Christiansen & Bellinger 1980, Yoshii & Suhardjno 1989, Mendonça & Fernandes 2007, Soto-Adames et al. 2008).
description: Published as part of Bellini, Bruno C., Cipola, Nikolas G. & Godeiro, Nerivânia N., 2015, New species of Lepidocyrtus Bourlet and Entomobrya Rondani (Collembola: Entomobryoidea: Entomobryidae) from Brazil, pp. 227-242 in Zootaxa 4027 (2) on page 228, DOI: 10.11646/zootaxa.4027.2.3, http://zenodo.org/record/235815
PDP: Physics-Based Character Animation via Diffusion Policy
Creators: name: Truong, Takara E.
name: Piseno, Michael
name: Xie, Zhaoming
name: Liu, C. Karen
Publisher: name: arXiv
Year: 2024
Subjects: subject: Graphics (cs.GR)
subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Generating diverse and realistic human motion that can physically interact with an environment remains a challenging research area in character animation. Meanwhile, diffusion-based methods, as proposed by the robotics community, have demonstrated the ability to capture highly diverse and multi-modal skills. However, naively training a diffusion policy often results in unstable motions for high-frequency, under-actuated control tasks like bipedal locomotion due to rapidly accumulating compounding errors, pushing the agent away from optimal training trajectories. The key idea lies in using RL policies not just for providing optimal trajectories but for providing corrective actions in sub-optimal states, giving the policy a chance to correct for errors caused by environmental stimulus, model errors, or numerical errors in simulation. Our method, Physics-Based Character Animation via Diffusion Policy (PDP), combines reinforcement learning (RL) and behavior cloning (BC) to create a robust diffusion policy for physics-based character animation. We demonstrate PDP on perturbation recovery, universal motion tracking, and physics-based text-to-motion synthesis.
Additional file 5: Table S5. of Interaction of smoking and obesity susceptibility loci on adolescent BMI: The National Longitudinal Study of Adolescent to Adult Health
Creators: name: Young, Kristin
name: Graff, Misa
name: North, Kari
name: Richardson, Andrea
name: Mohlke, Karen
name: Lange, Leslie
name: Lange, Ethan
name: Harris, Kathleen
name: Gordon-Larsen, Penny
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Established BMI loci used in present analysis. (DOCX 31 kb)
Torodora digna Lecithocera
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Torodora
Torodora digna

description: 157. Torodora digna (Meyrick, 1918b: 105) (Lecithocera)
Type locality: India, Assam, Khasi Hills [Now in Meghalaya]
Distribution: Indian records: Meghalaya. Global records: China.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 74, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Torodora eupatris Lecithocera
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Torodora
Torodora eupatris

description: 158. Torodora eupatris (Meyrick, 1910b: 443) (Lecithocera)
Type locality: India, Assam, Khasi Hills [Now in Meghalaya]
Distribution: Indian records: Meghalaya.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 74, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526