cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Cusps in the center of galaxies: a real conflict with observations or a numerical artefact of cosmological simulations?
Creators: name: Baushev, A. N.
name: del Valle, L.
name: Campusano, L. E.
name: Escala, A.
name: Muñoz, R. R.
name: Palma, G. A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Galaxy observations and N-body cosmological simulations produce conflicting dark matter halo density profiles for galaxy central regions. While simulations suggest a cuspy and universal density profile (UDP) of this region, the majority of observations favor variable profiles with a core in the center. In this paper, we investigate the convergency of standard N-body simulations, especially in the cusp region, following the approach proposed by \protect{\citep{13}}. We simulate the well known Hernquist model using the SPH code Gadget-3 and consider the full array of dynamical parameters of the particles. We find that, although the cuspy profile is stable, all integrals of motion characterizing individual particles suffer strong unphysical variations along the whole halo, revealing an effective interaction between the test bodies. This result casts doubts on the reliability of the velocity distribution function obtained in the simulations. Moreover, we find unphysical Fokker-Planck streams of particles in the cusp region. The same streams should appear in cosmological N-body simulations, being strong enough to change the shape of the cusp or even to create it. Our analysis, based on the Hernquist model and the standard SPH code, strongly suggests that the UDPs generally found by the cosmological N-body simulations may be a consequence of numerical effects. A much better understanding of the N-body simulation convergency is necessary before a 'core-cusp problem' can properly be used to question the validity of the CDM model.
description: 7 pages, 5 figures, accepted to JCAP
An analysis of English-Thai translation of cartoon motion pictures
Creators: name: Somachriyakul, Wasana
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Linguistics Program, School of Communication Arts and Critical Enquiry, Faculty of Humanities and Social Sciences, La Trobe University, Bundoora.
Siauw Giok Tjhan : bicultural leader in emerging Indonesia
Creators: name: Djin, Siauw Tiong
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and post graduate students can use the link in the Reference field.
Inflation from Supergravity with Gauged R-symmetry in de Sitter Vacuum
Creators: name: Antoniadis, I.
name: Chatrabhuti, A.
name: Isono, H.
name: Knoops, R.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the cosmology of a recent model of supersymmetry breaking, in the presence of a tuneable positive cosmological constant, based on a gauged shift symmetry of a string modulus that can be identified with the string dilaton. The minimal spectrum of the `hidden' supersymmetry breaking sector consists then of a vector multiplet that gauges the shift symmetry of the dilaton multiplet and when coupled to the MSSM leads to a distinct low energy phenomenology depending on one parameter. Here we study the question if this model can also lead to inflation by identifying the dilaton with the inflaton. We find that this is possible if the Kähler potential is modified by a term that has the form of NS5-brane instantons, leading to an appropriate inflationary plateau around the maximum of the scalar potential, depending on two extra parameters. This model is consistent with present cosmological observations without modifying the low energy particle phenomenology associated to the minimum of the scalar potential.
description: 19 pages, 5 figures, References added
Typed Design Patterns for the Functional Era
Creators: name: Crichton, Will
Publisher: name: arXiv
Year: 2023
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: This paper explores how design patterns could be revisited in the era of mainstream functional programming languages. I discuss the kinds of knowledge that ought to be represented as functional design patterns: architectural concepts that are relatively self-contained, but whose entirety cannot be represented as a language-level abstraction. I present four concrete examples embodying this idea: the Witness, the State Machine, the Parallel Lists, and the Registry. Each pattern is implemented in Rust to demonstrate how careful use of a sophisticated type system can better model each domain construct and thereby catch user mistakes at compile-time.
description: To appear at FUNARCH'23 @ ICFP
(201386) Herbert James Leigh-Bennett
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The music of politics - politics in music : the choral miniature repertoire of first generation Macedonian composers ; a re-assessment of Macedonian musical development
Creators: name: Sapundzijev, Mary
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the Reference field.
Maternity-service provision in Victoria, and the development and evaluation of a public health programme aimed at first-time parents
Creators: name: Buultjens, Melissa
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Public Health, Faculty of Health Sciences, La Trobe University, Bundoora.
Electronic supplementary material for sampling procedure, model outputs and habitat parameters from Linking bacteria, volatiles and insects on carrion: the role of temporal and spatial factors regulating inter-kingdom communication via volatiles
Creators: name: von Hoermann, Christian
name: Weithmann, Sandra
name: Sikorski, Johannes
name: Nevo, Omer
name: Szpila, Krzysztof
name: Grzywacz, Andrzej
name: Grunwald, Jan-Eric
name: Reckel, Frank
name: Overmann, Jörg
name: Steiger, Sandra
name: Ayasse, Manfred
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60408 Genomics

description: Data logger temperature profiles, listed decomposition stages, sampling procedure for capturing cadaveric volatiles, carrion exposition setup, collinearity plots, ADD0-ranges, GAMM, Bray-Curtis, Jaccard and Gaussian model outputs and verification plot of the temporal correlation pattern revealed in the analysis, habitat variables and their respective values of experimental forest sites
Investigations of the ferroelectric to paraelectric phase transition of vinyliden-fluoride trifluoroethylene copolymer thin films by electromechanical interferometry
Creators: name: Böhmer, Roland
name: Urayama, K.
name: Kircher, O.
name: Neher, D.
Publisher: name: American Institute of Physics
Year: 1999
Subjects: subject: 530

description: Electrostrictive and piezoelectric properties for a 1.3 µm thick film of a vinylidenefluoride/trifluoroethylene copolymer exhibiting a ferroelectric-to-paraelectric phase transition have been investigated as a function of temperature by means of electromechanical interferometry. The electrostriction remarkably increases in the vicinity of the phase transition temperature according to a sharp increase in the dielectric constant. For the unpoled sample in the ferroelectric phase with a polydomain structure in which the local spontaneous polarization is macroscopically cancelled out, the dependence of the electrostriction on the square of the applied electric field is nonlinear in the ferroelectric phase, while it is linear in the paraelectric phase. A theoretical model which takes into account the nonlinear dielectric constant can quantitatively explain the nonlinear contribution to the electrostriction in the vicinity of the ferroelectric–paraelectric phase transition, but it underestimates the contribution in the ferroelectric phase. Interactions within and/or between the ferroelectric domains in the polydomain structure are expected to contribute significantly to the nonlinear electrostriction. For poled samples a pronounced inverse-piezoelectric effect is measured. The achieved polarization and its temperature dependence are almost the same as for thicker films reported in earlier studies, obtained by different experimental techniques.
Level Structures of $^{56,58}$Ca Cast Doubt on a doubly magic $^{60}$Ca
Creators: name: Chen, S.
name: Browne, F.
name: Doornenbal, P.
name: Lee, J.
name: Obertelli, A.
name: Tsunoda, Y.
name: Otsuka, T.
name: Chazono, Y.
name: Hagen, G.
name: Holt, J. D.
name: Jansen, G. R.
name: Ogata, K.
name: Shimizu, N.
name: Utsuno, Y.
name: Yoshida, K.
name: Achouri, N. L.
name: Baba, H.
name: Calvet, D.
name: Château, F.
name: Chiga, N.
name: Corsi, A.
name: Cortés, M. L.
name: Delbart, A.
name: Gheller, J. -M.
name: Giganon, A.
name: Gillibert, A.
name: Hilaire, C.
name: Isobe, T.
name: Kobayashi, T.
name: Kubota, Y.
name: Lapoux, V.
name: Liu, H. N.
name: Motobayashi, T.
name: Murray, I.
name: Otsu, H.
name: Panin, V.
name: Paul, N.
name: Rodriguez, W.
name: Sakurai, H.
name: Sasano, M.
name: Steppenbeck, D.
name: Stuhl, L.
name: Sun, Y. L.
name: Togano, Y.
name: Uesaka, T.
name: Wimmer, K.
name: Yoneda, K.
name: Aktas, O.
name: Aumann, T.
name: Chung, L. X.
name: Flavigny, F.
name: Franchoo, S.
name: Gasparic, I.
name: Gerst, R. -B.
name: Gibelin, J.
name: Hahn, K. I.
name: Kim, D.
name: Koiwai, T.
name: Kondo, Y.
name: Koseoglou, P.
name: Lehr, C.
name: Linh, B. D.
name: Lokotko, T.
name: MacCormick, M.
name: Moschner, K.
name: Nakamura, T.
name: Park, S. Y.
name: Rossi, D.
name: Sahin, E.
name: Söderström, P. -A.
name: Sohler, D.
name: Takeuchi, S.
name: Törnqvist, H.
name: Vaquero, V.
name: Wagner, V.
name: Wang, S.
name: Werner, V.
name: Xu, X.
name: Yamada, H.
name: Yan, D.
name: Yang, Z.
name: Yasuda, M.
name: Zanetti, L.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Gamma decays were observed in $^{56}$Ca and $^{58}$Ca following quasi-free one-proton knockout reactions from $^{57,59}$Sc beams at $\approx 200$ MeV/nucleon. For $^{56}$Ca, a $γ$ ray transition was measured to be 1456(12) keV, while for $^{58}$Ca an indication for a transition was observed at 1115(34) keV. Both transitions were tentatively assigned as the $2^+_1 \rightarrow 0^+_{gs}$ decays, and were compared to results from ab initio and conventional shell-model approaches. A shell-model calculation in a wide model space with a marginally modified effective nucleon-nucleon interaction depicts excellent agreement with experiment for $2^+_1$ level energies, two-neutron separation energies, and reaction cross sections, corroborating the formation of a new nuclear shell above the $N$ = 34 shell. Its constituents, the $0f_{5/2}$ and $0g_{9/2}$ orbitals, are almost degenerate. This degeneracy precludes the possibility for a doubly magic $^{60}$Ca and potentially drives the dripline of Ca isotopes to $^{70}$Ca or even beyond.
description: 8 pages, 3 figures
Witness protection in Thailand and mutual assistance in criminal matters between Thailand and Australia: proposals for reform
Creators: name: Meeboonsalang, Namtaee
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Juridical Science to the School of Law, Faculty of Business, Economics and Law, La Trobe University, Bundoora.
The political orientations and political involvement of the Indonesian Officer Corps, 1945-1966 : the Siliwangi Division and the army headquarters
Creators: name: Sundhaussen, Ulf
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the Reference field.
(201388) John Ansell Day
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Experimental classification of multi-spin coherence under the full rotation group
Creators: name: Suter, Dieter
name: Pearson, J. G.
Publisher: name: Elsevier
Year: 2002
Subjects: subject: 530

description: The density operator of a coupled nuclear spin system often includes multi-spin coherences representing correlations between different spins. The generation and evolution of these coherences is governed by the dipole-dipole interactions between the spins and thus contains information about nuclear structure. Different multi-spin coherences may be distinguished by their behaviour under rotations. The maximum information extractable is determined by the irreducible representations of the full rotation group SO (3). By comparing the effect of rotation with various angles and rotation axes one can determine the expansion coefficients of the spin density operator in a basis of irreducible tensor operators. Experimentally, the rotation of the spins is achieved with rf pulses.
Fezolinetant: First Approval
Creators: name: Lee, Arnold
Publisher: name: Adis Journals
Year: 2023
Subjects: Medicine

description: Declarations Funding The preparation of this review was not supported by any external funding. Authorship and Conflict of interest During the peer review process the manufacturer of the agent under review was offered an opportunity to comment on the article. Changes resulting from any comments received were made by the authors on the basis of scientific completeness and accuracy. A. Lee is a salaried employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. All authors contributed to the review and are responsible for the article content. Ethics approval, Consent to participate, Consent to publish, Availability of data and material, Code availability Not applicable. Additional information about this Adis Drug Review can be found here. Abstract  Fezolinetant (VEOZAH™) is an oral, small molecule, neurokinin 3 receptor (NK3R) antagonist, which is being developed by Astellas Pharma Inc. for the treatment of moderate to severe vasomotor symptoms (VMS) or hot flashes due to menopause. Inhibiting NK3R-mediated signalling in the central nervous system is a non-hormonal strategy to modulate the activity of neurones that are associated with thermoregulation, thereby reducing the frequency and severity of VMS. Fezolinetant received its first approval in the USA in May 2023 for the treatment of moderate to severe VMS due to menopause. This article summarizes the milestones in the development of fezolinetant leading to this first approval in this indication. © Springer Nature Switzerland AG 2023
Universality of single qudit gates
Creators: name: Sawicki, Adam
name: Karnas, Katarzyna
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: Group Theory (math.GR)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We consider the problem of deciding if a set of quantum one-qudit gates $\mathcal{S}=\{g_1,\ldots,g_n\}\subset G$ is universal, i.e if the closure $\overline{}$ is equal to $G$, where $G$ is either the special unitary or the special orthogonal group. To every gate $g$ in $\mathcal{S}$ we asign its image under the adjoint representation $\mathrm{Ad}_g$, where $\mathrm{Ad}:G\rightarrow SO(\mathfrak{g})$ and $\mathfrak{g}$ is the Lie algebra of $G$. The necessary condition for the universality of $\mathcal{S}$ is that the only matrices that commute with all $\mathrm{Ad}_{g_i}$'s are proportional to the identity. If in addition there is an element in $$ whose Hilbert-Schmidt distance from the centre of $G$ belongs to $]0,\frac{1}{\sqrt{2}}]$, then $\mathcal{S}$ is universal. Using these we provide a simple algorithm that allows deciding the universality of any set of $d$-dimensional gates in a finite number of steps and formulate the general classification theorem.
description: Significantly improved universality criteria and presentation. A simple algorithm that allows deciding the universality of any set of gates in a finite number of steps added and discussed. Accepted in AHP
(201389) George Hobson Day
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The acquisition and use of English verb patterns by Singapore students of English
Creators: name: Seow, Thiam Chew Anthony
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the Reference field.
Cancer passage : continuity and discontinuity in terminal illness
Creators: name: Parker, Judith M.
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the Reference field.
Attitudes toward infidelity behaviours: considering correlating factors and scaling the perceived intensity of extradyadic behaviours
Creators: name: Dennison, Joanne M.
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Psychology in Counselling Psychology to the School of Public Health, Faculty of Health Sciences, La Trobe University, Bundoora.
External Cavity Diode Laser Setup with Two Interference Filters
Creators: name: Martin, Alexander
name: Baus, Patrick
name: Birkl, Gerhard
Publisher: name: arXiv
Year: 2016
Subjects: subject: Optics (physics.optics)
subject: Atomic Physics (physics.atom-ph)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We present an external cavity diode laser setup using two identical, commercially available interference filters operated in the blue wavelength range around 450 nm. The combination of the two filters decreases the transmission width, while increasing the edge steepness without a significant reduction in peak transmittance. Due to the broad spectral transmission of such interference filters compared to the internal mode spacing of blue laser diodes, an additional locking scheme, based on Hänsch-Couillaud locking to a cavity, has been added to improve the stability. The laser is stabilized to a line in the tellurium spectrum via saturation spectroscopy, and single-frequency operation for a duration of two days is demonstrated by monitoring the error signal of the lock and the piezo drive compensating the length change of the external resonator due to air pressure variations. Additionally, transmission curves of the filters and the spectra of a sample of diodes are given.
description: improved manuscript (accepted for publication in Applied Physics B, 2016)
Effect of Shock Heating on the Stability of Laser-Driven Targets
Creators: name: Boehly, T. R.
name: Delettrez, J. A.
name: Knauer, J. P.
name: Meyerhofer, D. D.
name: Yaakobi, B.
Publisher: name: The American Physical Society
Year: 2001
Subjects: subject: 530

description: Physical Review Letters
Glassy dynamics of poly(2-vinyl-pyridine) brushes with varying grafting density
Creators: name: Neubauer, Nils
name: Winkler, René
name: Tress, Martin
name: Uhlmann, Petra
name: Reiche, Martin
name: Kipnusu, Wycliffe Kiprop
name: Kremer, Friedrich
Publisher: name: London : Royal Soc. of Chemistry
Year: 2015
Subjects: subject: Acrylic monomers
subject: Glass transition
subject: Molecular dynamics
subject: Reaction kinetics
subject: Broadband dielectric spectroscopy
subject: 530

description: The molecular dynamics of poly(2-vinyl-pyridine) (P2VP) brushes is measured by Broadband Dielectric Spectroscopy (BDS) in a wide temperature (250 K to 440 K) and broad spectral (0.1 Hz to 1 MHz) range. This is realized using nanostructured, highly conductive silicon electrodes being separated by silica spacers as small as 35 nm. A “grafting-to”-method is applied to prepare the P2VP-brushes with five different grafting densities (0.030 nm−2 to 0.117 nm−2), covering the “true-brush” regime with highly stretched coils and the “mushroom-to-brush” transition regime. The film thickness ranges between 1.8 to 7.1 (±0.2) nm. Two relaxations are observed, an Arrhenius-like process being attributed to fluctuations in the poly(glycidyl-methacrylate) (PGMA) linker used for the grafting reaction and the segmental dynamics (dynamic glass transition) of the P2VP brushes. The latter is characterized by a Vogel–Fulcher–Tammann dependence similar to bulk P2VP. The results can be comprehended considering the length scale on which the dynamic glass transition (≤1 nm) takes place.
A grammar of Pamosu
Creators: name: Tupper, Ian D.
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Centre for Research on Language Diversity, La Trobe University, Bundoora, Victoria.

The public version of this thesis does not contain all material submitted for examination.
Cross-validation estimation of covariance parameters under fixed-domain asymptotics
Creators: name: Bachoc, Francois
name: Lagnoux, Agnes
name: Nguyen, Thi Mong Ngoc
Publisher: name: arXiv
Year: 2016
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: We consider a one-dimensional Gaussian process having exponential covariance function. Under fixed-domain asymptotics, we prove the strong consistency and asymptotic normality of a cross validation estimator of the microergodic covariance parameter. In this setting, Ying [40] proved the same asymptotic properties for the maximum likelihood estimator. Our proof includes several original or more involved components, compared to that of Ying. Also, while the asymptotic variance of maximum likelihood does not depend on the triangular array of observation points under consideration, that of cross validation does, and is shown to be lower and upper bounded. The lower bound coincides with the asymptotic variance of maximum likelihood. We provide examples of triangular arrays of observation points achieving the lower and upper bounds. We illustrate our asymptotic results with simulations, and provide extensions to the case of an unknown mean function. To our knowledge, this work constitutes the first fixed-domain asymptotic analysis of cross validation.
Measurement of Instability Growth in a Magnetized Z Pinch in the Finite-Larmor-Radius Regime
Creators: name: Coppins, M.
name: Dangor, A. E.
name: Davies, H. M.
name: Haines, M. G.
Publisher: name: The American Physical Society
Year: 2001
Subjects: subject: 530

description: Physical Review Letters
SAR296968, a Novel Selective Na+/Ca2+ Exchanger Inhibitor, Improves Ca2+ Handling and Contractile Function in Human Atrial Cardiomyocytes
Creators: name: Hegner, Philipp
name: Drzymalski, Marzena
name: Biedermann, Alexander
name: Memmel, Bernadette
name: Durczok, Melanie
name: Wester, Michael
name: Floerchinger, Bernhard
name: Provaznik, Zdenek
name: Schmid, Christof
name: Zausig, York
name: Maier, Lars S.
name: Wagner, Stefan
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: CARDIAC SARCOPLASMIC-RETICULUM; SODIUM-CALCIUM EXCHANGER; HEART-FAILURE; VENTRICULAR MYOCYTES; NA/CA EXCHANGE; NA+-CA2+ EXCHANGER; SPARKS; FIBRILLATION; EXPRESSION; RELEASE; Na+/Ca2+ exchanger; NCX; HFpEF; SAR296968
subject: 610 Medizin

description: Background: In reverse-mode, cardiac sodium-calcium exchanger (NCX) can increase the cytoplasmic Ca2+ concentration in response to high intracellular Na+ levels, which may contribute to diastolic contractile dysfunction. Furthermore, increased spontaneous Ca2+ release from intracellular stores can activate forward mode NCX. The resulting transient inward current causes delayed afterdepolarization (DAD)-dependent arrhythmias. Moreover, recently, NCX has been associated with impaired relaxation and reduced cardiac function in heart failure with preserved ejection fraction (HFpEF). Since NCX is upregulated in human chronic atrial fibrillation (AF) as well as heart failure (HF), specific inhibition may have therapeutic potential. Objective: We tested the antiarrhythmic, lusitropic and inotropic effects of a novel selective NCX-inhibitor (SAR296968) in human atrial myocardium. Methods and Results: Right atrial appendage biopsies of 46 patients undergoing elective cardiac surgery in a predominant HFpEF cohort (n = 24/46) were investigated. In isolated human atrial cardiomyocytes, SAR296968 reduced the frequency of spontaneous SR Ca2+ release events and increased caffeine transient amplitude. In accordance, in isolated atrial trabeculae, SAR296968 enhanced the developed tension after a 30 s pause of electrical stimulation consistent with reduced diastolic sarcoplasmic reticulum (SR) Ca2+ leak. Moreover, compared to vehicle, SAR296968 decreased steady-state diastolic tension (at 1 Hz) without impairing developed systolic tension. Importantly, SAR296968 did not affect the safety parameters, such as resting membrane potential or action potential duration as measured by patch clamp. Conclusion: The novel selective NCX-inhibitor SAR296968 inhibits atrial pro-arrhythmic activity and improves diastolic and contractile function in human atrial myocardium, which may have therapeutic implications, especially for treatment of HFpEF.
Water Use in Global Livestock Production—Opportunities and Constraints for Increasing Water Productivity
Creators: name: Heinke, Jens
name: Lannerstad, Mats
name: Gerten, Dieter
name: Havlík, Petr
name: Herrero, Mario
name: Notenbaert, An Maria Omer
name: Hoff, Holger
name: Müller, Christoph
Publisher: name: [New York] : Wiley
Year: 2020
Subjects: subject: livestock
subject: water productivity
subject: water use
subject: 550

description: Increasing population, change in consumption habits, and climate change will likely increase the competition for freshwater resources in the future. Exploring ways to improve water productivity especially in food and livestock systems is important for tackling the future water challenge. Here we combine detailed data on feed use and livestock production with Food and Agriculture Organization of the United Nations (FAO) statistics and process-based crop-water model simulations to comprehensively assess water use and water productivity in the global livestock sector. We estimate that, annually, 4,387 km3 of blue and green water is used for the production of livestock feed, equaling about 41% of total agricultural water use. Livestock water productivity (LWP; protein produced per m3 of water) differs by several orders of magnitude between livestock types, regions, and production systems, indicating a large potential for improvements. For pigs and broilers, we identify large opportunities to increase LWP by increasing both feed water productivity (FWP; feed produced per m3 of water) and feed use efficiency (FUE; protein produced per kg of feed) through better crop and livestock management. Even larger opportunities to increase FUE exist for ruminants, while the overall potential to increase their FWP is low. Substantial improvements of FUE can be achieved for ruminants by supplementation with feed crops, but the lower FWP of these feed crops compared to grazed biomass limits possible overall improvements of LWP. Therefore, LWP of ruminants, unlike for pigs and poultry, does not always benefit from a trend toward intensification, as this is often accompanied by increasing crop supplementation.
(201387) Maud Agnes Barchard
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Emergent horizon, Hawking radiation and chaos in the collapsed polymer model of a black hole
Creators: name: Brustein, Ram
name: Medved, A. J. M.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We have proposed that the interior of a macroscopic Schwarzschild black hole (BH) consists of highly excited, long, closed, interacting strings and, as such, can be modeled as a collapsed polymer. It was previously shown that the scaling relations of the collapsed-polymer model agree with those of the BH. The current paper further substantiates this proposal with an investigation into some of its dynamical consequences. In particular, we show that the model predicts, without relying on gravitational effects, an emergent horizon. We further show that the horizon fluctuates quantum mechanically as it should and that the strength of the fluctuations is inversely proportional to the BH entropy. It is then demonstrated that the emission of Hawking radiation is realized microscopically by the quantum-induced escape of small pieces of string, with the rate of escape and the energy per emitted piece both parametrically matching the Hawking temperature. We also show, using standard methods from statistical mechanics and chaos theory, how our model accounts for some other known properties of BHs. These include the accepted results for the scrambling time and the viscosity-to-entropy ratio, which in our model apply not only at the horizon but throughout the BH interior.
description: 41 pages, 4 figures, added introductory material and figures. Belated updated version to match the published version. Results unchanged
Lorentz-Covariant Spin Operator for Spin 1/2 Massive Fields As a Physical Observable
Creators: name: Choi, Taeseung
name: Han, Yeong Deok
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We derive a relativistic-covariant spin operator for massive case directly from space-time symmetry in Minkowski space-time and investigate the physical properties of a derived spin operator. In the derivation we require only two conditions: First, a spin operator should be the generator of the SU(2) little group of the Poincare group. Second, a spin operator should covariantly transform under the Lorentz transformation. A space inversion transformation is shown to play a role to derive a unique relativistic-covariant spin operator, we call the field spin operator, whose eigenvalue labels the spin of a massive (classical) field that provides the irreducible representation space of the Poincare group. The field spin becomes the covariant spin in the covariant Dirac representation, which is shown to be the only spin that describes the Wigner rotation properly in the covariant Dirac representation. Surprisingly, the field spin also gives the non-covariant spin, which is the FW spin for the positive energy state. We also show that the field spin operator is the unique spin operator that generate the (internal) SU(2) little group transformation of the Poincare group properly.
description: Published version is found in the Journal reference
Dispersive coupling between light and a rare-earth ion doped mechanical resonator
Creators: name: Mølmer, Klaus
name: Coq, Yann Le
name: Seidelin, Signe
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: By spectrally hole burning an inhomogeneously broadened ensemble of ions while applying a controlled perturbation, one can obtain spectral holes that are functionalized for maximum sensitivity to different perturbations. We propose to use such hole burnt structures for the dispersive optical interaction with rare-earth ion dopants whose frequencies are sensitive to crystal strain due to the bending motion of a crystal cantilever. A quantitative analysis shows that good optical sensitivity to the bending motion is obtained if a magnetic field gradient is applied across the crystal during hole burning, and that the resulting opto-mechanical coupling strength is sufficient for observing quantum features such as zero point vibrations.
A Fast Iterative Method for Chandrasekhar's H-functions for General Laws of Scattering
Creators: name: Kawabata, Kiyoshi
Publisher: name: arXiv
Year: 2016
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: This work shows that notable acceleration of the speed of calculating Chandrasekhar's H-functions for general laws of scattering with an iterative method can be realized by supplying a starting pproximation produced by the following procedure: (i) in the cases of azimuth-angle independent Fourier components, values of the isotropic scattering H-function given by an accurate yet simple-to-apply formula, in particular, the one by Kawabata and Limaye (Astrophys. and Space Sci. Vol. 332, 365-371, 2011 DOI 10.1007/s10509-010-0512-x; see also Astrophys. and Space Sci. Vol. 348, 601, 2013 DOI 10.1007/1009-013-1589-9, for erratum), and (ii) for azimuth-angle dependent Fourier components, an already obtained solution of the next lower order term. The paper has been published in Astrophys. and Space Sci. Vol. 358, 32-38 (2015) DOI 10.1007/s10509-015-2434-0, and the final publication is available at link.springer.com.
description: 10 pages, 0 figure, 4 tables
α-Synuclein cytotoxicity in Dictyostelium: a model of Parkinson's disease
Creators: name: Fernando, Sanjanie G.
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Department of Microbiology, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora.
Impact of plasma jet vacuum ultraviolet radiation on reactive oxygen species generation in bio-relevant liquids
Creators: name: Jablonowski, H.
name: Bussiahn, R.
name: Hammer, M.U.
name: Weltmann, K.-D.
name: Von Woedtke, T.
name: Reuter, S.
Publisher: name: [S.l.] : American Institute of Physics
Year: 2015
Subjects: subject: Atmospheric pressure
subject: Binary alloys
subject: Cell culture
subject: Electron spin resonance spectroscopy
subject: Paramagnetic resonance
subject: 530

description: Plasma medicine utilizes the combined interaction of plasma produced reactive components. These are reactive atoms, molecules, ions, metastable species, and radiation. Here, ultraviolet (UV, 100–400 nm) and, in particular, vacuum ultraviolet (VUV, 10–200 nm) radiation generated by an atmospheric pressure argon plasma jet were investigated regarding plasma emission, absorption in a humidified atmosphere and in solutions relevant for plasma medicine. The energy absorption was obtained for simple solutions like distilled water (dH2O) or ultrapure water and sodium chloride (NaCl) solution as well as for more complex ones, for example, Rosewell Park Memorial Institute (RPMI 1640) cell culture media. As moderate stable reactive oxygen species, hydrogen peroxide (H2O2) was studied. Highly reactive oxygen radicals, namely, superoxide anion (O2•−) and hydroxyl radicals (•OH), were investigated by the use of electron paramagnetic resonance spectroscopy. All species amounts were detected for three different treatment cases: Plasma jet generated VUV and UV radiation, plasma jet generated UV radiation without VUV part, and complete plasma jet including all reactive components additionally to VUV and UV radiation. It was found that a considerable amount of radicals are generated by the plasma generated photoemission. From the experiments, estimation on the low hazard potential of plasma generated VUV radiation is discussed.
From prospectus to belle edition : investigations in the luxury booktrade in eighteenth and early nineteenth-century France
Creators: name: Gray, Patricia Ann
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the Reference field.
Laboratory Study of Collisionless Magnetic Reconnection
Creators: name: Ji, H.
name: Yoo, J.
name: Fox, W.
name: Yamada, M.
name: Argall, M.
name: Egedal, J.
name: Liu, Y. -H.
name: Wilder, R.
name: Eriksson, S.
name: Daughton, W.
name: Bergstedt, K.
name: Bose, S.
name: Burch, J.
name: Torbert, R.
name: Ng, J.
name: Chen, L. -J.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: A concise review is given on the past two decades' results from laboratory experiments on collisionless magnetic reconnection in direct relation with space measurements, especially by Magnetospheric Multiscale (MMS) mission. Highlights include spatial structures of electromagnetic fields in ion and electron diffusion regions as a function of upstream symmetry and guide field strength; energy conversion and partition from magnetic field to ions and electrons including particle acceleration; electrostatic and electromagnetic kinetic plasma waves with various wavelengths; and plasmoid-mediated multiscale reconnection. Combined with the progress in theoretical, numerical, and observational studies, the physics foundation of fast reconnection in colisionless plasmas has been largely established, at least within the parameter ranges and spatial scales that were studied. Immediate and long-term future opportunities based on multiscale experiments and space missions supported by exascale computation are discussed, including dissipation by kinetic plasma waves, particle heating and acceleration, and multiscale physics across fluid and kinetic scales.
description: 40 pages, 15 figures
The Solar Neighborhood XXXVIII. Results from the CTIO/SMARTS 0.9m: Trigonometric Parallaxes for 151 Nearby M Dwarf Systems
Creators: name: Winters, Jennifer G.
name: Sevrinsky, R. Andrew
name: Jao, Wei-Chun
name: Henry, Todd J.
name: Riedel, Adric R.
name: Subasavage, John P.
name: Lurie, John C.
name: Ianna, Philip A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present 160 new trigonometric parallaxes for 151 M dwarf systems from the REsearch Consortium On Nearby Stars (RECONS) group's long-term astrometry/photometry program at the CTIO/SMARTS 0.9m telescope. Most systems (124 or 82%) are found to lie within 25 pc. The stars have 119 mas/yr < mu < 828 mas/yr and 3.85 < (V-K) < 8.47. Among these are 58 systems from the SuperCOSMOS-RECONS (SCR) search, discovered via our proper motion trawls of the SuperCOSMOS digitized archival photographic plates, while the remaining stars were suspected via photometric distance estimates to lie nearby. Sixteen are systems that are newly discovered via astrometric perturbations to be binaries, many of which are ideal for accurate mass determinations due to their proximity and orbital periods on the order of a decade. A variability analysis of the stars presented, two-thirds of which are new results, shows six of the stars to vary by more than 20 mmag. This effort brings the total number of parallaxes for M dwarf systems measured by RECONS to nearly 500 and increases by 26% the number of southern M dwarf systems with accurate trigonometric parallaxes placing them within 25 pc.
description: Accepted for publication to The Astronomical Journal; pre-print format; updated Astrometry table with parallax results to match those in final submitted & accepted AJ paper (9 parallax updates)
Transgenic white clover for enhanced yield and performance: trait dissection, trait stacking and phenomics
Creators: name: Vala, Bhuwaneshwariba H.
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Master of Science to the Department of Botany, School of Life Science, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora, Victoria.

The public version of this thesis does not contain all material submitted for examination.

White clover (Trifolium repens L.) is one of the dominant dairy pasture legume species in temperate regions of Australia and is a key pasture legume in other temperate regions around the world. Efficient and profitable cultivation of this highly beneficial pasture crop is hampered by various abiotic and biotic stresses. Major problems associated with white clover cultivation in Australia are: rising soil acidity, aluminium toxicity, and maintenance of high biomass production in suboptimal environments. The focus of this research is to improve tolerance to soil aluminium and increase biomass production and utilization of phosphorus fertilisers through trait stacking in transgenic white clover. A construct directed at ameliorating aluminium toxicity was engineered by placing the white clover nodule enhanced malate dehydrogenase (ne MDH) coding region and terminator under the control of a root enhanced phosphate transporter (Tr PT1) promoter, also from white clover. For increased biomass an isopentenyl transferase (ipt) gene from A. tumefaciens was placed under the control of a developmentally regulated promoter from the Arabidopsis thaliana Myb32 gene and the ipt terminator. Transgenic white clover plants were developed using an Agrobacteriummediated transformation system, containing the above mentioned agronomically valuable transgenes and the selectable marker hygromycin phosphotransferase (hph). Molecular analysis of independent transgenic plants confirmed the presence of both TrPT1:TrneMDH:TrneMDH+atmyb32:ipt:ipt and atmyb32:ipt:ipt Transformation efficiency was higher with a single transgene as compared to multiple cassettes. Selected transgenic lines were analysed for delayed leaf xvii senescence and aluminium tolerance. A wide spectrum of phenotypes were observed ranging from below mean to high performance as compared to isogenic controls (wild type). A further detailed expression analysis of these plants may help explain these results. However this research provides evidence that transgene stacking in white clover is possible and can potentially help to enhance Aluminium tolerance and increased biomass production.
Collapse of Resilience Patterns in Generalized Lotka-Volterra Dynamics and Beyond
Creators: name: Tu, Chengyi
name: Grilli, Jacopo
name: Schuessler, Friedrich
name: Suweis, Samir
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: Recently, a theoretical framework aimed at separating the roles of dynamics and topology in multi-dimensional systems has been developed (Gao et al, \textit{Nature}, Vol 530:307 (2016)). The validity of their method is assumed to hold depending on two main hypothesis: $(i)$ The network determined by the the interaction between pairs of nodes has negligible degree correlations; $(ii)$ The node activities are uniform across nodes on both the drift and pair-wise interaction functions. Moreover, the authors consider only positive (mutualistic) interactions. Here we show the conditions proposed by Gao and collaborators are neither sufficient nor necessary to guarantee that their method works in general, and validity of their results are not independent of the model chosen within the class of dynamics they considered. Indeed we find that a new condition poses effective limitations to their framework and we provide quantitative predictions of the quality of the one dimensional collapse as a function of the properties of interaction networks and stable dynamics using results from random matrix theory. We also find that multi-dimensional reduction may work also for interaction matrix with a mixture of positive and negative signs, opening up application of the framework to food-webs, neuronal networks and social/economic interactions.