cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Benefits and disadvantages of combination therapy with imeglimin and metformin in patients with type 2 diabetes
Creators: name: Ito, Hiroyuki
name: Tsugami, Emiko
name: I, Chiaki
name: Miura, Shun
name: Matsumoto, Suzuko
name: Inoue, Hideyuki
name: Antoku, Shinichi
name: Yamasaki, Tomoko
name: Mori, Toshiko
name: Togane, Michiko
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Hematology
subject: Computational Biology

description: We retrospectively examined the benefits and disadvantages of adding imeglimin to metformin therapy in patients with type 2 diabetes. Ninety-four patients with type 2 diabetes who had been administered imeglimin were included in the safety analysis set (SAS). Sixty-four patients who had been treated with imeglimin for over 6 months were included in the full analysis set (FAS). The primary outcome was the change in HbA1c levels in the FAS. The secondary outcomes were gastrointestinal adverse events (AEs) in the SAS and changes in body weight and FIB-4 in theFAS. In the SAS, gastrointestinal AEs occurred in 15 of 40 (38%) metformin users and 6 of 54 (11%) non-users. In the FAS, HbA1c levels were significantly reduced in both metformin users (n = 27, baseline, 8.5 ± 1.1%;6 months, 7.7 ± 1.2%) and non-users (n = 37, baseline, 8.0 ± 0.9%; 6 months,7.4 ± 0.9%). While body weight (from 72.0 ± 20.5 kg to 70.9 ± 20.8 kg) and FIB-4 (from 1.27 ± 0.57 to 1.17 ± 0.49) significantly decreased in metformin users, they did not significantly differ in non-users. Adding imeglimin to metformin therapy demonstrated favorable reductions in HbA1c, body weight, and FIB-4 in patients with type 2 diabetes, although it was associated with the incidence of gastrointestinal AEs. UMIN000055241.
Additional file 1 of Incidence and mortality trends of neglected tropical diseases and malaria in China and ASEAN countries from 1990 to 2019 and its association with the socio-demographic index
Creators: name: Liu, Qiao
name: Yan, Wenxin
name: Qin, Chenyuan
name: Du, Min
name: Wang, Yaping
name: Liu, Min
name: Liu, Jue
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 1. Supplementary tables and figures of Incidence and mortality trends of neglected tropical diseases and malaria in China and ASEAN countries from 1990 to 2019 and its association with the Socio-demographic Index.
Optical Spin Initialization of Nitrogen Vacancy Centers in a 28Si-Enriched 6H-SiC Crystal for Quantum Technologies
Creators: name: Murzakhanov, F. F.
name: Sadovnikova, M. A.
name: Mamin, G. V.
name: Shurtakova, D. V.
name: Mokhov, E. N.
name: Kazarova, O. P.
name: Gafurov, M. R.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: High-spin defect centers in crystal matrices are used in quantum computing technologies, highly sensitive sensors, and single-photon sources. In this work, optically active nitrogen-vacancy color centers NV in a 28Si-enriched (nuclear spin I = 0) 6H-28SiC crystal have been studied using the photoinduced (980 nm) high-frequency (94 GHz, 3.4 T) pulsed electron paramagnetic resonance method at a temperature of 150 K. Three structurally nonequivalent types of NV- centers with axial symmetry have been identified and their spectroscopic parameters have been determined. Long spin-lattice, T1=1.3 ms, and spin-spin, T2=59 us, ensemble relaxation times of NV- centers with extremely narrow (450 kHz) absorption lines allow highly selective excitation of resonant transitions between sublevels caused by the weak hyperfine interaction (A = 1 MHz) with 14N (I = 1) nuclei for the quantum manipulation of the electron spin magnetization.
PREPARATION OF NUCLEAR EXTRACTS FROM HeLa CELLS
Creators: name: Shahid, Muhammad Tahman
name: Khair-Ul-Bariyah, Syeda
Publisher: name: European Chemical Bulletin
Year: 2014

description: Stem cells are the powerful cells derived both from human and animal source. They have the ability to divide innumerably and differentiate into different cell types in the body. HeLa cells are the first immortal human cell lines grown in culture. These cell lines have proved beneficial in the development of polio vaccines and study of various viral cells. The present review aims to cover the studies done through nuclear extracts prepared from HeLa cells. Nuclear extracts from HeLa cells have been used to study the activation of ATM and ATR by double stranded DNA breaks, production of transcriptionally active extracts, analysis of RNA splicing in vitro using T7 RNA polymerase-derived splicing substrate RNAs and purification and characterization of proteins. By using these nuclear extracts, the mutational study of proteins still needs to be done to know exact reason of many unknown diseases. Wide variations of pH in extract preparation should be tested to get variations in extract obtained and methods should be modified for desired polypeptide length and to work with extracts at nano scale.
description: European Chemical Bulletin, Vol 3, No 4 (2014): European Chemical Bulletin
Affordance Perception by a Knowledge-Guided Vision-Language Model with Efficient Error Correction
Creators: name: Burghouts, Gertjan
name: Schaaphok, Marianne
name: van Bekkum, Michael
name: Meijer, Wouter
name: Hillerström, Fieke
name: van Mil, Jelle
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Mobile robot platforms will increasingly be tasked with activities that involve grasping and manipulating objects in open world environments. Affordance understanding provides a robot with means to realise its goals and execute its tasks, e.g. to achieve autonomous navigation in unknown buildings where it has to find doors and ways to open these. In order to get actionable suggestions, robots need to be able to distinguish subtle differences between objects, as they may result in different action sequences: doorknobs require grasp and twist, while handlebars require grasp and push. In this paper, we improve affordance perception for a robot in an open-world setting. Our contribution is threefold: (1) We provide an affordance representation with precise, actionable affordances; (2) We connect this knowledge base to a foundational vision-language models (VLM) and prompt the VLM for a wider variety of new and unseen objects; (3) We apply a human-in-the-loop for corrections on the output of the VLM. The mix of affordance representation, image detection and a human-in-the-loop is effective for a robot to search for objects to achieve its goals. We have demonstrated this in a scenario of finding various doors and the many different ways to open them.
description: 15 pages
INHIBITION OF CORROSION OF ALUMINIUM IN ALKALINE MEDIUM BY POLY(VINYL ALCOHOL) (PVA)
Creators: name: Kalaivani, Rajadurai
name: Aras, P. Thillai
name: Rajendran, S.
Publisher: name: European Chemical Bulletin
Year: 2014

description: The inhibition efficiency  of polyvinylalcohol (PVA) in controlling corrosion  of aluminium in well water in the absence and presence of Zn2+  has beenevaluated by weight loss method. The formulation consisting of  250 ppm of PVA and 25 ppm of Zn2+ offers 85 % inhibition efficiency. It is found that the inhibition efficiency  of PVA increases by addition of Zn2+  ion. A synergistic effect exists between PVA and Zn2+. The mechanistic aspects of corrosion inhibition have been studied using polarization study. Also FTIR spectra reveal that the protective film consists of  PVA - Zn2+ complex and  Zn(OH)2. The scanning  electron microscopy confirms the protection of aluminium surface by strong adsorption of PVA.  A suitable mechanism for corrosion inhibition is proposed based on the results from the above studies.
description: European Chemical Bulletin, Vol 3, No 4 (2014): European Chemical Bulletin
ENERGY EMISSIONS OF SPARK DISCHARGE UNDER WATER
Creators: name: Izdebski, Thomas
name: Dors, Miroslaw
name: Mizeraczyk, Jerzy
Publisher: name: European Chemical Bulletin
Year: 2014

description: The recent focus of research with electrohydraulic discharges is on bacteria and microorganism inactivation. The processes and main biocidal effects in which this occurs are not fully understood.  In this paper a study of energy emission from electrohydraulic spark discharge is presented. The spark discharge was generated in a cylindrical reactor 25 mm in diameter made of PTFE between a stainless steel hollow needle electrode and a steel rod electrode. Distilled water was used and the flow was 30 ml/min. The gap between the electrodes was 3 mm. Spark discharge energy was measured to be 1.2-1.4 J. Measurements show that over 50% of this energy is used for heating of the reactor and electrodes, and about 2% for acoustic waves. The rest of the discharge energy, i.e. ~0.54 J, is distributed among UV/Vis radiation, production of primary active species and ultrasonic.
description: European Chemical Bulletin, Vol 3, No 8 (2014): European Chemical Bulletin
Disparities in Emergency Medical Services Termination of Resuscitation Practices for Patients with Out-of-Hospital Cardiac Arrest
Creators: name: Naas, Christopher J.
name: Nickel, Lauren B.
name: Aufderheide, Tom P.
name: Weston, Benjamin W.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Neuroscience
Biotechnology
Biological Sciences not elsewhere classified
Developmental Biology
Science Policy

description: There are well-described racial, ethnic, and gender-based inequities following out-of-hospital cardiac arrest (OHCA). Few studies have analyzed disparities in emergency medical services (EMS) termination of resuscitation (TOR) practices. This purpose of this study was to identify inequities in duration of prehospital resuscitation prior to TOR. A retrospective cohort of adult (≥18 years-old), non-traumatic OHCA events in a single metropolitan, fire-based EMS system was evaluated. Duration of resuscitation prior to prehospital TOR was separately evaluated among racial/ethnic (Black, Hispanic, and White) and gender (female and male) groups using a multivariable linear regression model. Variables in the model included bystander cardiopulmonary resuscitation (CPR) provision, arrest witnessed status, initial rhythm (shockable versus non-shockable), and patient age. Multiple imputation was used to account for missing data entries where duration of resuscitation was not documented. Incidence of hospital transport between racial/ethnic and gender groups was also assessed. Between February 1, 2020 and February 28, 2023, 3700 patients met inclusion criteria, of which 1,895 (51.2%) had field TOR and 1,328/1,895 had a documented time of TOR. When controlling for arrest witnessed status, bystander CPR provision, initial shockable rhythm, and subject age, Black race [24.1 min (95% confidence interval 21.2–27.0, p < 0.001)] and Hispanic ethnicity [23.7 min (95% CI 20.0–27.5, p = 0.03)] were associated with shorter duration of resuscitation compared to White race [25.8 min (95% CI 23.9–27.7)]. These racial inequities persisted when using multiple imputation modeling. There was no difference in duration of resuscitation between female [24.3 min (95% CI 22.4–26.2)] and male gender [24.7 min (95% CI 21.8–27.5), p = 0.46]. There were no differences in incidence of hospital transport. This study identified inequities in prehospital termination of resuscitation practices following OHCA. Black and Hispanic patients, as compared to White patients, received approximately 2-min-shorter prehospital resuscitative efforts prior to TOR despite controlling for bystander CPR, witnessed status, initial rhythm, and patient age. There were no gender-based differences in prehospital duration of resuscitation.
Reviewer_2_v.1 – Supplemental material for Use of monoclonal antibodies for allergic bronchopulmonary aspergillosis in patients with asthma and cystic fibrosis: literature review
Creators: name: Eraso, Isabel C.
name: Sangiovanni, Saveria
name: Morales, Eliana I.
name: Fernández-Trujillo, Liliana
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 110203 Respiratory Diseases

description: Supplemental material, Reviewer_2_v.1 for Use of monoclonal antibodies for allergic bronchopulmonary aspergillosis in patients with asthma and cystic fibrosis: literature review by Isabel C. Eraso, Saveria Sangiovanni, Eliana I. Morales and Liliana Fernández-Trujillo in Therapeutic Advances in Respiratory Disease
Prehospital and Emergency Department Vital Sign Abnormalities Among Injured Children
Creators: name: Ramgopal, Sriram
name: Gorski, Jillian K.
name: Martin-Gill, Christian
name: Spurrier, Ryan G.
name: Chaudhari, Pradip P.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: Cancer
subject: Mental Health

description: Vital signs are a critical component in the assessment of the injured child. We compared vital sign abnormalities among injured children in the prehospital setting to those in the emergency department (ED) and evaluated the predictive value of each for the presence of major trauma. We performed a multi-agency and multicenter retrospective study of injured children within a county-based emergency medical services (EMS) system between 2010 and 2021, including injured children (<18 years) transported to the hospital. We compared prehospital vital signs for heart rate (HR), respiratory rate (RR), and systolic blood pressure (SBP) in the prehospital and ED setting. Using the Standard Triage Assessment Tool to define major trauma, we constructed multivariable models to evaluate the association of prehospital and ED vital sign abnormalities for major trauma. We included 21,298 encounters (median age 13 years, IQR 6-16), with major trauma was present in 3,606 (16.9%). In the prehospital setting, abnormal vital signs were reported in 25.7% for HR, 14.6% for RR, and 24.3% for SBP. ED measurements recorded a higher proportion of abnormal HR (28.2%) and RR (21.3%), and slightly lower proportion with abnormal SBP (21.8%). Cohen’s Kappa was fair for HR (0.27) and SBP (0.20), but slight for RR (0.09). Prehospital vital signs most strongly associated with major trauma included tachypnea (odds ratio [OR] 2.7, 95% confidence interval (CI 2.4–3.1) and bradypnea (OR 1.7, 95% CI 1.4–1.9). ED vital signs most strongly associated with major trauma included hypotension (OR 2.4, 95% CI 2.1–2.7) and tachypnea (OR 1.8, 95% CI 1.6–2.0). Prehospital and ED vital signs demonstrated similar performance in predicting major trauma (area under the receiver operator characteristic curve (AUROC 0.63); 95% CI 0.61–0.64 for prehospital; 0.63; 95% CI, 0.61–0.64 for ED). When combining prehospital and ED vital signs into a single model, predictive power increased (AUROC 0.66, 95% CI 0.65–0.67). We identified poor correlation between prehospital and ED vital signs. In both settings, vital sign abnormalities were associated with major trauma. The combined use of prehospital and ED vital signs improved predictive value for major trauma, suggesting potential for future integration into trauma triage tools.
Open-World Visual Reasoning by a Neuro-Symbolic Program of Zero-Shot Symbols
Creators: name: Burghouts, Gertjan
name: Hillerström, Fieke
name: Walraven, Erwin
name: van Bekkum, Michael
name: Ruis, Frank
name: Sijs, Joris
name: van Mil, Jelle
name: Dijk, Judith
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: We consider the problem of finding spatial configurations of multiple objects in images, e.g., a mobile inspection robot is tasked to localize abandoned tools on the floor. We define the spatial configuration of objects by first-order logic in terms of relations and attributes. A neuro-symbolic program matches the logic formulas to probabilistic object proposals for the given image, provided by language-vision models by querying them for the symbols. This work is the first to combine neuro-symbolic programming (reasoning) and language-vision models (learning) to find spatial configurations of objects in images in an open world setting. We show the effectiveness by finding abandoned tools on floors and leaking pipes. We find that most prediction errors are due to biases in the language-vision model.
description: 12 pages
Epidemiology of Neonatal Prehospital Care at the San Diego (US) – Tijuana (Mexico) International Border
Creators: name: Yarlagadda, Sriyansh
name: Hazboun, Michael
name: Vilke, Gary
name: Farah, Jennifer
name: Donofrio-Odmann, J. Joelle
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Computational Biology

description: Neonates, infants 30 days of age or younger are understudied in prehospital emergencies. Our objective was to describe prehospital assessment and care for patients <30 days of age at the San Diego–Tijuana Point of Entry (POE). Additional objectives included describing assessments, care, frequency, and level of care for newborns brought to the border by Mexican ambulances. This was a retrospective analysis from January 1, 2014, to January 01, 2020, of all 9-1-1 calls involving patients <30 days of age at the San Diego POEs. The 9-1-1 responses to newly delivered patients were “newborns”. Patients who were not immediately post-delivery were “neonates.” Patient demographics, response intervals, clinician interventions, and dispositional data were collected from electronic patient records. Descriptive statistics were applied. A total of 57 patients <30 days of age were included. With 27 newborn patients, 15 were delivered by emergency medical services (EMS) personnel (27, 55.6%). Initial appearance, pulse, grimace, activity, and respiration (APGAR) scores were 8–10 in 44.4% and 5–7 in 29.6%. Procedures included newborn care (88.9%), advanced life support (ALS) assessment (63.0%), and warming (59.3%). There were five patients that had stimulation, 7 received oxygen, and 3 received Bag-Valve-Mask (BVM) ventilation. No serial heart rates were documented. Regarding 30 neonates, the predominant method of transport to the POE was Mexican ambulance (n 16, 53.3%). Medications administered included oxygen (n 16, 53.3%) and albuterol/ipratropium (n 1, 3.3%). Procedures included ALS assessment (n 19, 63.3%), pulse oximetry (n 22, 73.3%), and 3-lead electrocardiogram (n 8, 26.7%). Three patients (10%) received BVM. Mexican Ambulances brought 16 neonates. A physician or nurse was present in 37.5% of transfers, 50% were incubated, 25% intubated, 37.5% on supplemental oxygen, and 71% had preexisting intravenous access. These were not interfacility transfers but were 9-1-1 activations by U.S. border agents; and 14 neonates did not arrive via Mexican ambulance. Their complaints were respiratory distress (n 7, 50%) and Brief Resolved Unexplained Episode (n 4, 28.6%). We found that 9-1-1 transports at the San Diego–Tijuana POE for patients <30 days were few and involved resuscitation, neonates in Mexican ambulances with specialized equipment, physicians, and unfamiliar medications. Neonates arriving via private transport had respiratory distress and BRUE.
Disparities in Emergency Medical Services Termination of Resuscitation Practices for Patients with Out-of-Hospital Cardiac Arrest
Creators: name: Naas, CJ
name: Nickel, LB
name: Aufderheide, TP
name: Weston, BW
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Neuroscience
Biotechnology
Biological Sciences not elsewhere classified
Developmental Biology
Science Policy

description: There are well-described racial, ethnic, and gender-based inequities following out-of-hospital cardiac arrest (OHCA). Few studies have analyzed disparities in emergency medical services (EMS) termination of resuscitation (TOR) practices. This purpose of this study was to identify inequities in duration of prehospital resuscitation prior to TOR. A retrospective cohort of adult (≥18 years-old), non-traumatic OHCA events in a single metropolitan, fire-based EMS system was evaluated. Duration of resuscitation prior to prehospital TOR was separately evaluated among racial/ethnic (Black, Hispanic, and White) and gender (Female and Male) groups using a multivariable linear regression model. Variables in the model included bystander cardiopulmonary resuscitation (CPR) provision, arrest witnessed status, initial rhythm (shockable versus non-shockable), and patient age. Multiple imputation was used to account for missing data entries where duration of resuscitation was not documented. Incidence of hospital transport between racial/ethnic and gender groups was also assessed. Between February 1, 2020 and February 28, 2023, 3700 patients met inclusion criteria, of which 1895 (51.2%) had field TOR and 1328/1895 had a documented time of TOR. When controlling for arrest witnessed status, bystander CPR provision, initial shockable rhythm, and subject age, Black race (24.1 minutes (95% confidence interval 21.2-27.0, p < 0.001)) and Hispanic ethnicity (23.7 minutes (95% CI 20.0-27.5, p = 0.03)) were associated with shorter duration of resuscitation compared to White race (25.8 minutes (95% CI 23.9-27.7)). These racial inequities persisted when using multiple imputation modeling. There was no difference in duration of resuscitation between female (24.3 minutes (95% CI 22.4-26.2)) and male gender (24.7 minutes (95%CI 21.8-27.5), p = 0.46). There were no differences in incidence of hospital transport. This study identified inequities in prehospital termination of resuscitation practices following OHCA. Black and Hispanic patients, as compared to White patients, received approximately 2-minute-shorter prehospital resuscitative efforts prior to TOR despite controlling for bystander CPR, witnessed status, initial rhythm, and patient age. There were no gender-based differences in prehospital duration of resuscitation.
A Heterogeneous Legal Landscape Governs Community AED Use: Crowdsourced United States AED Legal Review and Gap Analysis
Creators: name: Adriansen, David J.
name: Fischberg, Bryan L.
name: Marill, Keith A.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Space Science
Cell Biology
Pharmacology
Biotechnology
Biological Sciences not elsewhere classified
Science Policy

description: Automatic External Defibrillators (AEDs) are a tremendous advance in the care of victims of out-of-hospital cardiac arrest. We sought to define and assess the legal landscape regarding Automatic External Defibrillators (AEDs) in the United States (U.S.). We performed a retrospective study of all state and federal laws relevant to the use of AEDs outside the hospital in the U.S. In the first of three phases, we searched a database of U.S. laws and regulations (“rules”) using broad relevant search terms. Teams of two investigators reviewed all rules identified for relevance to ten realms: location, acquisition, deployment, liability, training, accessibility, maintenance, registration, interface, and reporting. We termed the application of each rule to a single realm an “action,” so each rule could have one or more actions. In Phase 2, a third reviewer resolved any differences or discrepancies. A separate team of investigators confirmed or identified a “URL” online address for each rule. In Phase 3, we performed quantitative assessments of all included rules using summary statistics and Cohen’s kappa to assess reviewer reliability. We made qualitative assessments for each realm across all jurisdictions using SWOT (Strengths, Weaknesses, Opportunities, and Threats) analyses. Nine hundred twenty-one rules, which included 1,987 actions, were deemed relevant to defibrillator access and use in the community, with a mean of 17.4 (SD 14.0) rules and 37.5 (SD 35.0) actions per jurisdiction, suggesting large heterogeneity in actions across states. There were 21 federal rules, including 42 actions. Qualitative analyses revealed that some states have successfully implemented AED training programs and public awareness campaigns, but uneven public awareness, cost, liability, and overly complex or stringent rules have posed barriers to successful AED deployment and use. We have provided a focused overview of U.S. rules governing community AEDs. We found high heterogeneity across states and a limited federal floor of rules. It is hoped this report can be used to improve legislation and resulting future successful AED use.
Genre of Music Festivals as a Predictor for Medical Utilization Rate
Creators: name: van Dijken, G. D.
name: Hofsteede, J. S. W. R.
name: Hoek, A. E.
name: Dekker, D.
name: de Lange, D. W.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: The medical utilization rates (MUR) can be applied to anticipate necessary medical resources at mass gatherings. The MUR describes the number of patients per thousand attendees. The aim of this observational study was to evaluate whether the type of music festival, Electronic Dance Music Festivals (EDMF) versus Mainstream, is related to the MUR and to drug-related incidents. We conducted a retrospective analysis of patient data from Event Medical Service B.V., a Dutch company, providing emergency care at many festivals in the Netherlands. Data were collected in an online database between February 2022 and August 2023. The number of patient contacts per festival type was recorded and patients requiring advanced medical care (unable to sit, potentially hemodynamically unstable, and/or requiring advanced medical care), were analyzed for drug-related causes. A total of 20,829 patients presented at 518 events with a total attendance of almost 7.5 million visitors. There were 253 EDMF events with a median attendance of 12,000 and 265 mainstream events with a median attendance of 10,000 per event. The average MUR for the EDMF group was higher compared to the Mainstream group (28.8 vs. 17.8, p < 0.001). A total of 1,732 patients needed advanced medical care. The proportion of drug-related cases among the patients needing advanced medical care, mainly stimulants and combined drug use, was 74% for the EDMF group compared to 52% in the mainstream group (p < 0.001). In this observational study we found a clear difference in MUR in Electronic Dance Music events compared to Mainstream events with a higher percentage of drug-related cases in patients with more severe conditions at EDMF events. Our findings may help to better plan scarce medical resources at mass gatherings in the music scene and suggest that EDMF need a targeted approach for more drug-related pathology.
Lightweight Uncertainty Quantification with Simplex Semantic Segmentation for Terrain Traversability
Creators: name: Dijk, Judith
name: Burghouts, Gertjan
name: Katyal, Kapil D.
name: Yeh, Bryanna Y.
name: Knuth, Craig T.
name: Fokkinga, Ella
name: Kasarla, Tejaswi
name: Mettes, Pascal
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: For navigation of robots, image segmentation is an important component to determining a terrain's traversability. For safe and efficient navigation, it is key to assess the uncertainty of the predicted segments. Current uncertainty estimation methods are limited to a specific choice of model architecture, are costly in terms of training time, require large memory for inference (ensembles), or involve complex model architectures (energy-based, hyperbolic, masking). In this paper, we propose a simple, light-weight module that can be connected to any pretrained image segmentation model, regardless of its architecture, with marginal additional computation cost because it reuses the model's backbone. Our module is based on maximum separation of the segmentation classes by respective prototype vectors. This optimizes the probability that out-of-distribution segments are projected in between the prototype vectors. The uncertainty value in the classification label is obtained from the distance to the nearest prototype. We demonstrate the effectiveness of our module for terrain segmentation.
description: 10 pages
Prehospital and emergency department vital sign abnormalities among injured children
Creators: name: Ramgopal, Sriram
name: Gorski, Jillian K.
name: Martin-Gill, Christian
name: Spurrier, Ryan G.
name: Chaudhari, Pradip P.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: Cancer
subject: Mental Health

description: Vital signs are a critical component in the assessment of the injured child. We compared vital sign abnormalities among injured children in the prehospital setting to those in the emergency department (ED) and evaluated the predictive value of each for the presence of major trauma. We performed a multi-agency and multicenter retrospective study of injured children within a county-based emergency medical services (EMS) system between 2010-2021, including injured children (<18 years) transported to the hospital. We compared prehospital vital signs for heart rate (HR), respiratory rate (RR), and systolic blood pressure (SBP) in the prehospital and ED setting. Using the Standard Triage Assessment Tool to define major trauma, we constructed multivariable models to evaluate the association of prehospital and ED vital sign abnormalities for major trauma. We included 21,298 encounters (median age 13 years, IQR 6-16), with major trauma was present in 3,606 (16.9%). In the prehospital setting, abnormal vital signs were reported in 25.7% for HR, 14.6% for RR, and 24.3% for SBP. ED measurements recorded a higher proportion of abnormal HR (28.2%) and RR (21.3%), and slightly lower proportion with abnormal SBP (21.8%). Cohen’s Kappa was fair for HR (0.27) and SBP (0.20), but slight for RR (0.09). Prehospital vital signs most strongly associated with major trauma included tachypnea (odds ratio [OR] 2.7, 95% confidence interval (CI 2.4-3.1) and bradypnea (OR 1.7, 95% CI 1.4-1.9). ED vital signs most strongly associated with major trauma included hypotension (OR 2.4, 95% CI 2.1-2.7) and tachypnea (OR 1.8, 95% CI 1.6-2.0). Prehospital and ED vital signs demonstrated similar performance in predicting major trauma (area under the receiver operator characteristic curve (AUROC 0.63); 95% CI 0.61-0.64 for prehospital; 0.63; 95% CI, 0.61-0.64 for ED). When combining prehospital and ED vital signs into a single model, predictive power increased (AUROC 0.66, 95% CI 0.65-0.67). We identified poor correlation between prehospital and ED vital signs. In both settings, vital sign abnormalities were associated with major trauma. The combined use of prehospital and ED vital signs improved predictive value for major trauma, suggesting potential for future integration into trauma triage tools.
Epidemiology of Neonate Prehospital Care at the San Diego (US) – Tijuana (Mexico) International Border
Creators: name: Yarlagadda, Sriyansh
name: Hazboun, Michael
name: Vilke, Gary
name: Farah, Jennifer
name: Donofrio-Odmann, J. Joelle
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Computational Biology

description: Neonates, infants 30 days of age or younger are understudied in prehospital emergencies. Our objective was to describe prehospital assessment and care for patients <30 days of age at the San Diego–Tijuana Point of Entry (POE). Additional objectives included describing assessments, care, frequency, and level of care for newborns brought to the border by Mexican ambulances. This was a retrospective analysis from January 1, 2014, to January 01, 2020, of all 9-1-1 calls involving patients <30 days of age at the San Diego POEs. The 9-1-1 responses to newly delivered patients were “newborns”. Patients who were not immediately post-delivery were “neonates.” Patient demographics, response intervals, clinician interventions, and dispositional data were collected from electronic patient records. Descriptive statistics were applied. A total of 57 patients <30 days of age were included. With 27 newborn patients, 15 were delivered by emergency medical services (EMS) personnel (27, 55.6%). Initial appearance, pulse, grimace, activity, and respiration (APGAR) scores were 8–10 in 44.4% and 5–7 in 29.6%. Procedures included newborn care (88.9%), advanced life support (ALS) assessment (63.0%), and warming (59.3%). There were five patients that had stimulation, 7 received oxygen, and 3 received Bag-Valve-Mask (BVM) ventilation. No serial heart rates were documented. Regarding 30 neonates, the predominant method of transport to the POE was Mexican ambulance (n 16, 53.3%). Medications administered included oxygen (n 16, 53.3%) and albuterol/ipratropium (n 1, 3.3%). Procedures included ALS assessment (n 19, 63.3%), pulse oximetry (n 22, 73.3%), and 3-lead electrocardiogram (n 8, 26.7%). Three patients (10%) received BVM. Mexican Ambulances brought 16 neonates. A physician or nurse was present in 37.5% of transfers, 50% were incubated, 25% intubated, 37.5% on supplemental oxygen, and 71% had preexisting intravenous access. These were not interfacility transfers but were 9-1-1 activations by U.S. border agents; and 14 neonates did not arrive via Mexican ambulance. Their complaints were respiratory distress (n 7, 50%) and Brief Resolved Unexplained Episode (n 4, 28.6%). We found that 9-1-1 transports at the San Diego–Tijuana POE for patients <30 days were few and involved resuscitation, neonates in Mexican ambulances with specialized equipment, physicians, and unfamiliar medications. Neonates arriving via private transport had respiratory distress and BRUE.
Genre of Music Festivals as a predictor for Medical Utilization Rate
Creators: name: van Dijken, G.D.
name: Hofsteede, J.S.W.R.
name: Hoek, A.E.
name: Dekker, D.
name: de Lange, D.W
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: The Medical Utilization Rates (MUR) can be applied to anticipate necessary medical resources at mass gatherings. The MUR describes the number of patients per thousand attendees. The aim of this observational study was to evaluate whether the type of music festival, Electronic Dance Music Festivals (EDMF) versus Mainstream, is related to the MUR and to drug-related incidents. We conducted a retrospective analysis of patient data from Event Medical Service B.V., a Dutch company, providing emergency care at many festivals in the Netherlands. Data were collected in an online database between February 2022 and August 2023. The number of patient contacts per festival type was recorded and patients requiring advanced medical care (unable to sit, potentially hemodynamically unstable and/or requiring advanced medical care), were analyzed for drug-related causes. A total of 20,829 patients presented at 518 events with a total attendance of almost 7.5 million visitors. There were 253 EDMF events with a median attendance of 12,000 and 265 mainstream events with a median attendance of 10,000 per event. The average MUR for the EDMF group was higher compared to the Mainstream group (28.8 vs. 17.8, p <0.001). A total of 1732 patients needed advanced medical care. The proportion of drug-related cases among the patients needing advanced medical care, mainly stimulants and combined drug use, was 74% for the EDMF group compared to 52% in the mainstream group (p <0.001). In this observational study we found a clear difference in MUR in Electronic Dance Music events compared to Mainstream events with a higher percentage of drug-related cases in patients with more severe conditions at EDMF events. Our findings may help to better plan scarce medical resources at mass gatherings in the music scene and suggest that EDMF need a targeted approach for more drug-related pathology.
title: Betriebs-Historik-Panel 1975-2020
Creators: name: Ganzer, Andreas
name: Schmucker, Alexandra
name: Stegmaier, Jens
name: Stüber, Heiko Berufsforschung
Publisher: name: Forschungsdatenzentrum der Bundesagentur für Arbeit (BA) im Institut für Arbeitsmarkt- und Berufsforschung (IAB)
Year: 2022

description: Das Betriebs-Historik-Panel (BHP) setzt sich aus Querschnittsdatensätzen ab dem Jahr 1975 für Westdeutschland und ab 1992 für Ostdeutschland zusammen. Jeder Querschnitt umfasst alle Betriebe des gesamtdeutschen Raumes, die zur Jahresmitte (Stichtag: 30.6.) in der Beschäftigten-Historik (BeH) erfasst sind. Von 1975 bis 1998 sind das alle Betriebe mit mindestens einem sozialversicherungspflichtig Beschäftigten. Ab 1999 zählen zu diesen Betrieben auch solche, die zwar keine sozialversicherungspflichtigen aber zumindest einen geringfügigen Beschäftigten aufweisen. Die einzelnen Querschnittsdatensätze können zu einem Panel verbunden werden. Dieser Datenreport beschreibt das Betriebs-Historik-Panel (BHP) 1975-2020.
Spectrum of creative agencies in AI-based art: analysis of art reviews
Creators: name: Loivaranta, Tikli
name: Hautala, Johanna
name: Lundman, Riina
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Mental Health

description: The relation between creativity and AI is an ongoing debate in artmaking. AI challenges the traditional understanding of who (or what) can be the creative agent and whether the outcomes are creative. Such a debate is visible in art reviews of AI-based art, but their analyses are missing from the research on AI and creativity. We analyse 39 AI art evaluations from key global newspapers to answer the following questions: how is creative agency discussed, and how are the evaluations of creative outcomes affected by the understandings of creative agency? Our results demonstrate a spectrum of creative agencies, which expands from four (human-centred, AI-centred, co-agency, assemblage) to seven (AI-assisted, AI-enchanted, and AI-improvised) agencies. Perceived creative agency is connected to the evaluation of artworks: Positive evaluations often consider human creative agency, but negative evaluations blame AI. These findings suggest that new ways to assess creativity are emerging in the AI era.
Additional file 1 of Progesterone attenuates Th17-cell pathogenicity in autoimmune uveitis via Id2/Pim1 axis
Creators: name: Liu, Xiuxing
name: Gu, Chenyang
name: Lv, Jianjie
name: Jiang, Qi
name: Ding, Wen
name: Huang, Zhaohao
name: Liu, Yidan
name: Su, Yuhan
name: Zhang, Chun
name: Xu, Zhuping
name: Wang, Xianggui
name: Su, Wenru
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Fig. S1. The effects of PRG on retinal cells during EAU. Fig. S2. The clustering strategies for scRNA-seq of CDLNs cells. Fig. S3. PRG reversed the EAU-induced inflammatory responses and PRG-related pathway disequilibrium. Fig. S4. The modulatory effects of PRG on CD4+ T cells. Fig. S5. The modulatory effects of PRG on Th17 cells. Fig. S6. The modulatory effects of PRG on Id2/Pim1 pathway in Th17 cells.
When Kropotkin met Lenin
Creators: name: Kinna, Ruth
Publisher: name: Humanities Commons
Year: 2017
Subjects: subject: Socialism
subject: Idea (Philosophy)
subject: History

description: Kropotkin’s meeting with Lenin in 1919 shows how contemporary concepts of vanguardism and prefiguration rely on concepts of revolution that have been historicised through the experience of the Russian Revolution. This fleeting single encounter also draws out a contrast between anarchist and Bolshevik ideas.   The risk of returning to Russian revolutionary history to re-examine anarchist and Bolshevik concepts of revolution is that it encourages a misleadingly bipolar narrative. However, the point is neither to deny the complexity of the revolution nor to show what divided anarchists from Bolsheviks, still less Marxists – as if there were no greys in this relationship. Rather it is to consider what Kropotkin’s analysis of revolution, advanced in the course of a revolutionary struggle, represented and where prefigurative ideas elaborated thereafter, stand in relation to it.
An automated homogenization processor for preparation of specimens for infectious organism and DNA detection
Creators: name: Huegel, William V.
name: Li, Xiaolin
name: Dong, Caixia
name: Liu, Ziye
name: Browne, Kenneth A.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Fecal specimens are important biomarker sources for parasitic and microbial infections, microbial imbalances and nucleic acids shed from colorectal cancers. Preparing feces manually for testing is messy, time consuming and requires substantial “hands-on” analyst time. The utility of an automated solid specimen preparation platform comprised of a robotic/imaging/fluidic instrument and consumables was evaluated. Further development included consumable improvements, benchmarking hands-on versus automated timing, and guard banding specimen inputs and mixing regimens. Biomarkers in processed filtrates were tested by microscopy, immunoassay, culturing, and qPCR. After optimization, the platform reproducibly processed samples in less than 2 min of hands-free time with element recovery ranging from 74%–93%. There was a high correlation between antigen measured in a new Giardia chemiluminescence immunoassay from dog specimens prepared manually or on the platform. Candida sp. were cultured from 4 of 6 processed dog specimens. Nucleosome and KRAS DNA were recovered with little difference between paired fresh or frozen processed specimens. Finally, fecal samples from 10 different domestic and exotic animals were shown to be successfully homogenized on the platform. The new platform has been integrated and optimized for processing a variety of specimens into suitable filtrates for multiple parasitological, gastrointestinal disease, and oncological tests, providing a valuable addition to clinical laboratories.
MPEC 2025-E92 : 2025 DM36
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2025
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2025 DM36

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: Establishment History Panel 1975-2020
Creators: name: Ganzer, Andreas
name: Schmucker, Alexandra
name: Stegmaier, Jens
name: Stüber, Heiko Berufsforschung
Publisher: name: Forschungsdatenzentrum der Bundesagentur für Arbeit (BA) im Institut für Arbeitsmarkt- und Berufsforschung (IAB)
Year: 2022

description: The Establishment History Panel (BHP) is composed of cross sectional datasets since 1975 for West Germany and 1992 for East Germany. Every cross section contains all the establishments in Germany which are covered by the IAB Employment History (BeH) on June 30th. These are all establishments with at least one employee liable to social security on the reference date. Establishments with no employee liable to social security but with at least one marginal part-time employee are included since 1999. The cross sections can be combined to form a panel. This data report describes the Establishment-History-Panel (BHP) 1975-2020.
sj-pdf-1-vas-10.1177_1708538120921005 - Supplemental material for Six-month results of stenting of the femoropopliteal artery and predictive value of interleukin-6: Comparison with high-sensitivity C-reactive protein
Creators: name: Guo, Songlin
name: Zhang, Zhang
name: Wang, Lei
name: Yuan, Liangxi
name: Bao, Junmin
name: Zhou, Jian
name: Jing, Zaiping
Publisher: name: SAGE Journals
Year: 2020
Subjects: Cardiology

description: Supplemental material, sj-pdf-1-vas-10.1177_1708538120921005 for Six-month results of stenting of the femoropopliteal artery and predictive value of interleukin-6: Comparison with high-sensitivity C-reactive protein by Songlin Guo, Zhang Zhang, Lei Wang, Liangxi Yuan, Junmin Bao, Jian Zhou and Zaiping Jing in Vascular
Contested Territory: Regional Development in France, 1934-1968
Creators: name: Wendeln, Matthew
Publisher: name: unknown
Year: 2011
Subjects: subject: City planning
subject: Industrial sociology
subject: History, Modern
subject: Cities and towns--Study and teaching
subject: France
subject: France--Paris
subject: Decolonization
subject: Area studies
subject: Economic history

description: This thesis shows how government intervention shaped the remapping of industry and population in postwar France. Combining a national perspective with local case studies, it analyzes the regional development programs organized around the new conceptual framework of aménagement du territoire. I address a core tension: industrial decentralization was a Keynesian social policy, which brought new jobs to impoverished areas, but it also undercut the power of Parisian labor and created a kaleidoscope of new regional inequalities. Three chapters trace the complex relationship between projects of urban "containment," rural preservation, and new ideals of Keynesian modernization from 1934 to 1955. I examine the decentralization of defense industries, programs to deindustrialize Paris, and battles to control provincial labor markets during new development. The following two chapters address, respectively, the institutional and discursive bases of redistributive regional policies and the role of decolonization in shaping debates on inequalities in France. Next, I take the Citroën car factory built in Rennes, Brittany, as a case study of new rural industrialization from Rennes' pro-growth municipal politics to the company's recruitment of peasant workers and the community's contestation of its new employer. A concluding chapter covers key shifts in French industry during the 1960s: Parisian contraction, branch-plant expansion, and new high-tech metropolises. This dissertation is at the junction of social science research-on industrial geography and territorial governance-and the history of French industry and labor, urban policy, and state economic intervention.