cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Implementation of a multiplanar pre-procedure planning technique for epidural and nerve root spinal procedures performed under fluoroscopy-guidance- effect on procedural radiation dose
Creators: name: Sheldon, James
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Interventional non-vascular
subject: Musculoskeletal spine
subject: Fluoroscopy
subject: CT
subject: Physics
subject: Radiation safety
subject: Dosimetric comparison

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To establish the radiation dose to the patient during a fluoroscopy guided transforaminal nerve root or transforaminal epidural injection at our institution. Determine whether there was a difference in radiation dose between the two fluoroscopy...
Living with ghosts in Horava-Lifshitz gravity
Creators: name: Ramazanov, S.
name: Arroja, F.
name: Celoria, M.
name: Matarrese, S.
name: Pilo, L.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider the branch of the projectable Horava-Lifshitz model which exhibits ghost instabilities in the low energy limit. It turns out that, due to the Lorentz violating structure of the model and to the presence of a finite strong coupling scale, the vacuum decay rate into photons is tiny in a wide range of phenomenologically acceptable parameters. The strong coupling scale, understood as a cutoff on ghosts' spatial momenta, can be raised up to $Λ\sim 10$ TeV. At lower momenta, the projectable Horava-Lifshitz gravity is equivalent to General Relativity supplemented by a fluid with a small positive sound speed squared ($10^{-42}\lesssim$) $c^2_s \lesssim 10^{-20}$, that could be a promising candidate for the Dark Matter. Despite these advantages, the unavoidable presence of the strong coupling obscures the implementation of the original Horava's proposal on quantum gravity. Apart from the Horava-Lifshitz model, conclusions of the present work hold also for the mimetic matter scenario, where the analogue of the projectability condition is achieved by a non-invertible conformal transformation of the metric.
description: 33 pages, 1 figure. The proof of an equivalence between the IR limit of the projectable Horava-Lifshitz gravity and the mimetic matter scenario is given in Appendix A. Version accepted for publication in JHEP
Theodor Kaluza's Theory of Everything: extended
Creators: name: Schindelbeck, Thomas
Publisher: name: Zenodo
Year: 2023
Subjects: elementary particles, fine-structure constant, strong interaction, gravitation, general relativity, Kaluza, TOE

description: Using a Kaluza-type of model, describing the laws of electromagnetism within the formalism of differential geometry, provides a coherent, comprehensive and quantitative description of phenomena related to particles, including the values for electroweak coupling constants, a convergent series of quantized particle energies with limits given by the energy values of the electron and the Higgs vacuum expectation value. The geometry of the solutions for spin 1/2 define 6 lepton-like and 6 quark-like entities with their corresponding electric charges and allow an accurate calculation of the magnetic moments of baryons. Electromagnetic and gravitational terms will be linked by a series expansion, the corresponding relation suggests the existence of a cosmological constant in the correct order of magnitude. The model can be expressed ab initio, necessary input parameters are the electromagnetic constants.
Amplitude-dependency of response of SI cortex to flutter stimulation
Creators: name: Chiu, Joannellyn S
name: Tannan, Vinay
name: Whitsel, Barry
name: Tommerdahl, Mark Allen
name: Simons, Stephen B
name: Favorov, Oleg
Publisher: name: BioMed Central Ltd
Year: 2005

description: Abstract Background It is established that increasing the amplitude of a flutter stimulus increases its perceived intensity. Although many studies have examined this phenomenon with regard to the responding afferent population, the way in which the intensity of a stimulus is coded in primary somatosensory cortex (SI) remains unclear. Results Optical intrinsic signal (OIS) imaging was used to study the evoked responses in SI of anesthetized squirrel monkeys by 25 Hz sinusoidal vertical skin displacement stimulation. Stimuli were 10 sec duration with a 50 sec inter-stimulus interval. Stimulus amplitude ranged from 50 to 400 microns and different amplitudes were interleaved. Control levels of activity were measured in the absence of stimulation, and used to compare with activation levels evoked by the different stimulus amplitudes. Stimulation of a discrete skin site on the forelimb evoked a prominent increase in absorbance within the forelimb representational region in cytoarchitectonic areas 3b and 1 of the contralateral hemisphere. An increase in stimulus amplitude led to a proportional increase in the magnitude of the absorbance increase in this region of areas 3b and 1 while surrounding cortex underwent a decrease in absorbance. Correlation maps revealed that as stimulus amplitude is increased, the spatial extent of the activated region in SI remains relatively constant, and the activity within this region increases progressively. Additionally, as stimulus amplitude is increased to suprathreshold levels, activity in the surround of the activated SI territory decreases, suggesting an increase in inhibition of neuronal activity within these regions. Conclusion Increasing the amplitude of a flutter stimulus leads to a proportional increase in absorbance within the forelimb representational region of SI. This most likely reflects an increase in the firing rate of neurons in this region of SI. The relatively constant spatial extent of this stimulus-evoked increase in absorbance suggests that an increase in the amplitude of a 25 Hz skin stimulus does not evoke a larger area of SI neuronal activation due to an amplitude-dependent lateral inhibitory effect that spatially funnels the responding SI neuronal population.
Estimate of the truncation error of a finite volume discretisation of the Navier-Stokes equations on colocated grids
Creators: name: Syrakos, Alexandros
name: Goulas, Apostolos
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Numerical Analysis (math.NA)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: A methodology is proposed for the calculation of the truncation error of finite volume discretisations of the incompressible Navier-Stokes equations on colocated grids. The truncation error is estimated by restricting the solution obtained on a given grid to a coarser grid and calculating the image of the discrete Navier-Stokes operator of the coarse grid on the restricted velocity and pressure field. The proposed methodology is not a new concept but its application to colocated finite volume discretisations of the incompressible Navier-Stokes equations is made possible by the introduction of a variant of the momentum interpolation technique for mass fluxes where the pressure-part of the mass fluxes is not dependent on the coefficients of the linearised momentum equations. The theory presented is supported by a number of numerical experiments. The methodology is developed for two-dimensional flows, but extension to three-dimensional cases should not pose problems.
title: Endovascular treatment of superior vena cava syndrome
Creators: name: Lahkim, Mohamed
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Interventional vascular
subject: Interventional vascular
subject: Interventional non-vascular
subject: CT
subject: Fluoroscopy
subject: Conventional radiography
subject: Venous access
subject: Diagnostic procedure
subject: Stents
subject: Embolism / Thrombosis

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: -To be familiar with the anatomy of the superior vena cava -To know the etiologies and physiopathology of superior vena cava syndrome (SCS). -To know the protocol and results of pre-therapeutic CT venography. -To deal with the indications and...
A new phenomenological Investigation of $KMR$ and $MRW$ $unintegrated$ parton distribution functions
Creators: name: Modarres, Majid
name: Hossenikhani, Hossein
name: Olanj, Naeimeh
name: Masouminia, Mohammadreza
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The longitudinal proton structure function, $F_L(x,Q^2)$, from the $k_t$ factorization formalism by using the unintegrated parton distribution functions (UPDF) which are generated through the KMR and MRW procedures. The LO UPDF of the KMR prescription is extracted, by taking into account the PDF of Martin et al, i.e. MSTW2008-LO and MRST99-NLO and next, the NLO UPDF of the MRW scheme is generated through the set of MSTW2008-NLO PDF as the inputs. The different aspects of $F_L(x,Q^2)$ in the two approaches, as well as its perturbative and non-perturbative parts are calculated. Then the comparison of $F_L(x,Q^2)$ is made with the data given by the ZEUS and H1 collaborations. It is demonstrated that the extracted $F_L(x,Q^2)$ based on the UPDF of two schemes, are consistent to the experimental data, and by a good approximation, they are independent to the input PDF. But the one developed from the KMR prescription, have better agreement to the data with respect to that of MRW. As it has been suggested, by lowering the factorization scale or the Bjorken variable in the related experiments, it may be possible to analyze the present theoretical approaches more accurately.
Transformation of SV40-immortalized human uroepithelial cells by 3-methylcholanthrene increases IFN- and Large T Antigen-induced transcripts
Creators: name: Crosby, Lynn M
Publisher: name: BioMed Central Ltd
Year: 2010

description: Abstract Background Simian Virus 40 (SV40) immortalization followed by treatment of cells with 3-methylcholanthrene (3-MC) has been used to elicit tumors in athymic mice. 3-MC carcinogenesis has been thoroughly studied, however gene-level interactions between 3-MC and SV40 that could have produced the observed tumors have not been explored. The commercially-available human uroepithelial cell lines were either SV40-immortalized (HUC) or SV40-immortalized and then 3-MC-transformed (HUC-TC). Results To characterize the SV40 - 3MC interaction, we compared human gene expression in these cell lines using a human cancer array and confirmed selected changes by RT-PCR. Many viral Large T Antigen (Tag) expression-related changes occurred in HUC-TC, and it is concluded that SV40 and 3-MC may act synergistically to transform cells. Changes noted in IFP 9-27, 2'-5' OAS, IF 56, MxA and MxAB were typical of those that occur in response to viral exposure and are part of the innate immune response. Because interferon is crucial to innate immune host defenses and many gene changes were interferon-related, we explored cellular growth responses to exogenous IFN-γ and found that treatment impeded growth in tumor, but not immortalized HUC on days 4 - 7. Cellular metabolism however, was inhibited in both cell types. We conclude that IFN-γ metabolic responses were functional in both cell lines, but IFN-γ anti-proliferative responses functioned only in tumor cells. Conclusions Synergism of SV40 with 3-MC or other environmental carcinogens may be of concern as SV40 is now endemic in 2-5.9% of the U.S. population. In addition, SV40-immortalization is a generally-accepted method used in many research materials, but the possibility of off-target effects in studies carried out using these cells has not been considered. We hope that our work will stimulate further study of this important phenomenon.
title: MR imaging of spinal bone marrow - how to interpret abnormalities
Creators: name: Heursen, Eva-Marie
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Metastases
subject: Infection
subject: Education and training
subject: Normal variants
subject: Localisation
subject: Education
subject: MR
subject: Musculoskeletal spine
subject: Bones

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To learn how to systematically analyze bone marrow abnormalities in the vertebral bodies of the spinal column seen on MRI, depending on associated findings such as fractures or intervertebral disc...
Atom addition reactions in interstellar ice analogues
Creators: name: Linnartz, Harold
name: Ioppolo, Sergio
name: Fedoseev, Gleb
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: This review paper summarizes the state-of-the-art in laboratory based interstellar ice chemistry. The focus is on atom addition reactions, illustrating how water, carbon dioxide and methanol can form in the solid state at astronomically relevant temperatures, and also the formation of more complex species such as hydroxylamine, an important prebiotic molecule, and glycolaldehyde, the smallest sugar, is discussed. These reactions are particularly relevant during the dark ages of star and planet formation, i.e., when the role of UV light is restricted. A quantitative characterization of such processes is only possible through dedicated laboratory studies, i.e., under full control of a large set of parameters such as temperature, atom-flux, and ice morphology. The resulting numbers, physical and chemical constants, e.g., barrier heights, reaction rates and branching ratios, provide information on the molecular processes at work and are needed as input for astrochemical models, in order to bridge the timescales typical for a laboratory setting to those needed to understand the evolutionary stages of the interstellar medium. Details of the experiments as well as the astrochemical impact of the results are discussed.
Adaptive Agent-Based SCADA System
Creators: name: Abbas, Hosny
name: Shaheen, Samir
name: Amin, Mohammed
Publisher: name: arXiv
Year: 2015
Subjects: subject: Systems and Control (eess.SY)
subject: Multiagent Systems (cs.MA)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Modern supervisory control and data acquisition (SCADA) systems comprise variety of industrial equipment such as physical control processes, logical control systems, communication networks, computers, and communication protocols. They are concerned with control and supervision of production control processes. Modern SCADA networks contain highly distributed information, control, and location. Moreover, they contain large number of heterogeneous components situated in highly changing and uncertain environments. As a result, engineering modern SCADA is a challenging issue and conventional engineering approaches are no longer suitable for them because of their increasing complexity and highly distribution. In this research, Multi-Agent Systems (MAS) are used to enable building adaptive agent-based SCADA system by modeling system components as agents in the micro level and as organizations or societies of agents in the macro level. A prototype has been implemented and evaluated within a simulation environment for demonstrating the adaptive behavior of the system-to-be, which results in continuous improvement of system performance.
description: 10
Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile
Creators: name: Muallem, Hind
name: Kuan, Pei Fen
name: Morgan, Douglas R.
name: Gulley, Margaret L
name: Speck, Olga
name: Banet, Natalie
name: Woodward, Kimberly
name: Tang, Weihua
name: Meyers, Michael O
Publisher: name: BioMed Central Ltd
Year: 2012

description: Abstract Background EBV DNA is found within the malignant cells of 10% of gastric cancers. Modern molecular technology facilitates identification of virus-related biochemical effects that could assist in early diagnosis and disease management. Methods In this study, RNA expression profiling was performed on 326 macrodissected paraffin-embedded tissues including 204 cancers and, when available, adjacent non-malignant mucosa. Nanostring nCounter probes targeted 96 RNAs (20 viral, 73 human, and 3 spiked RNAs). Results In 182 tissues with adequate housekeeper RNAs, distinct profiles were found in infected versus uninfected cancers, and in malignant versus adjacent benign mucosa. EBV-infected gastric cancers expressed nearly all of the 18 latent and lytic EBV RNAs in the test panel. Levels of EBER1 and EBER2 RNA were highest and were proportional to the quantity of EBV genomes as measured by Q-PCR. Among protein coding EBV RNAs, EBNA1 from the Q promoter and BRLF1 were highly expressed while EBNA2 levels were low positive in only 6/14 infected cancers. Concomitant upregulation of cellular factors implies that virus is not an innocent bystander but rather is linked to NFKB signaling (FCER2, TRAF1) and immune response (TNFSF9, CXCL11, IFITM1, FCRL3, MS4A1 and PLUNC), with PPARG expression implicating altered cellular metabolism. Compared to adjacent non-malignant mucosa, gastric cancers consistently expressed INHBA, SPP1, THY1, SERPINH1, CXCL1, FSCN1, PTGS2 (COX2), BBC3, ICAM1, TNFSF9, SULF1, SLC2A1, TYMS, three collagens, the cell proliferation markers MYC and PCNA, and EBV BLLF1 while they lacked CDH1 (E-cadherin), CLDN18, PTEN, SDC1 (CD138), GAST (gastrin) and its downstream effector CHGA (chromogranin). Compared to lymphoepithelioma-like carcinoma of the uterine cervix, gastric cancers expressed CLDN18, EPCAM, REG4, BBC3, OLFM4, PPARG, and CDH17 while they had diminished levels of IFITM1 and HIF1A. The druggable targets ERBB2 (Her2), MET, and the HIF pathway, as well as several other potential pharmacogenetic indicators (including EBV infection itself, as well as SPARC, TYMS, FCGR2B and REG4) were identified in some tumor specimens. Conclusion This study shows how modern molecular technology applied to archival fixed tissues yields novel insights into viral oncogenesis that could be useful in managing affected patients.
Complex splicing control of the human Thrombopoietin gene by intronic G runs - Image Analysis
Creators: name: Bernardes Silva, Martine
Publisher: name: Zenodo
Year: 2023

description: Image analysis for Figure 3D of Marcucci et al. (2007) Complex splicing control of the human Thrombopoietin gene by intronic G runs published in Nucleic Acids Research, Volume 35, Issue 1, 1 January 2007, Pages 132–142, https://doi.org/10.1093/nar/gkl965
title: Vasculitis: variety of findings in chest.
Creators: name: De la Via, Esperanza
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Vascular
subject: Respiratory system
subject: Lung
subject: Conventional radiography
subject: CT-High Resolution
subject: CT-Angiography
subject: Contrast agent-intravenous
subject: Inflammation
subject: Haemorrhage

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Vasculitis is a group of diseases in which inflammation of the vessel wall occurs causing the destructuring of the blood vessels. Lungs are commonly affects and involvement can be from the main pulmonary arteries to the alveolar...
Bouchea ehrenbergii Chamisso 1832
Creators: name: Pablo, Moroni
name: Nataly, O'Leary
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Verbenaceae
Bouchea
Bouchea ehrenbergii

description: Bouchea ehrenbergii Chamisso (1832: 253)
 Type (lectotype, designated here):— HAITI. “ S. Domingo ”, C. A. Ehrenberg s.n. (HAL 0115153!; isolectoype NY 1337397!).
 Protologue citation:—“Ex Insula San Domingo misit Carolus Ehrenberg, prope Port au Prince lectum.”
 Notes:—Chamisso (1832) described B. ehrenbergii based on a collection that was done by C. A. Ehrenberg in the island of “San Domingo”, near Port-au-Prince. Ehrenberg visited the French colony of Santo Domingo, now Haiti, from 1828 to 1831 (Urban 1901: 43), devoting his free time to plant collecting in this city and in Cap-Haïtien (Moscoso 1943: XXIX).
Moldenke (1940b: 100) cited as type material an Ehrenberg collection kept at B, indicating the geographical provenance as “ Santo Domingo, Dominican Republic, Hispaniola”. It is evident that Moldenke has misinterpreted the label on the specimen, referring the material as coming from Dominican Republic instead of Haiti. He also cited a sheet collected by Ehrenberg in Port-au-Prince (Moldenke 1940b: 103), supposedly housed in the Meisner Herbarium (NY), but this material could not be traced (A. Weiss, pers. comm).
 The specimen cited as type is no longer extant at B, because it was lost during the bombing of Berlin in the year 1943 (R. Vogt, pers. comm.). Fortunately, a photograph of the sheet kept at NY (A. Weiss, pers. comm.) allows us to declare that the specimen seemed to be original material since the handwriting on it matches with Chamisso’s calligraphy (Burdet 1974: 215 − 216). Thus, Moldenke’s statement is here interpreted according to the modern ICN (McNeill et al. 2012) as a lectotype designation.
Since this specimen is lost, a new lectotype is here proposed. Two specimens studied and annotated by Chamisso were located at HAL and NY; both elements agree with the diagnosis, and the locality cited in the protologue is covered by the label (Port-au-Prince was the capital of Santo Domingo in the time of Ehrenberg). Thus, these specimens are considered as original material for the name. The Ehrenberg material at HAL is annotated “ Bouchea Ehrenbergii Cham ” and “ S. Domingo ” by Chamisso, and contains a fertile branch with four flowers in a good state of preservation and two leaves. Despite the good state of conservation of the sheet at NY, the Ehrenberg material at HAL is here selected as the lectotype since it is more complete and agrees with the traditional and currant usage of the name of this species.
description: Published as part of Pablo, Moroni & Nataly, O'Leary, 2017, Typification of names in the genus Bouchea (Duranteae, Verbenaceae), pp. 211-216 in Phytotaxa 306 (3) on page 212, DOI: 10.11646/phytotaxa.306.3.3, http://zenodo.org/record/13696025
Lorentz violation naturalness revisited
Creators: name: Belenchia, Alessio
name: Gambassi, Andrea
name: Liberati, Stefano
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We revisit here the naturalness problem of Lorentz invariance violations on a simple toy model of a scalar field coupled to a fermion field via a Yukawa interaction. We first review some well-known results concerning the low-energy percolation of Lorentz violation from high energies, presenting some details of the analysis not explicitly discussed in the literature and discussing some previously unnoticed subtleties. We then show how a separation between the scale of validity of the effective field theory and that one of Lorentz invariance violations can hinder this low-energy percolation. While such protection mechanism was previously considered in the literature, we provide here a simple illustration of how it works and of its general features. Finally, we consider a case in which dissipation is present, showing that the dissipative behaviour does not percolate generically to lower mass dimension operators albeit dispersion does. Moreover, we show that a scale separation can protect from unsuppressed low-energy percolation also in this case.
description: 33 pages, 5 figures. Some typos corrected, this version accepted for publication in JHEP
Where are macrophage-tropic viruses?
Creators: name: Joseph, S
name: Schnell, G
name: Swanstrom, Ronald
Publisher: name: BioMed Central Ltd
Year: 2010

description: Eradication strategies must consider all cellular sources
of virus. During the course of infection, HIV-1 can
evolve to acquire new cell tropism. We have examined
virus in blood and cerebral spinal fluid to identify virus
capable of infecting macrophages.
title: Pediatric Fluoroscopy - Instructions, Clinical Pearls, and Radiation-Reduction Techniques
Creators: name: Imsande, Heather
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Education and training
subject: Congenital
subject: Acute
subject: Dynamic swallowing studies
subject: Cystography / Uretrography
subject: Barium enema
subject: Ultrasound
subject: Conventional radiography
subject: Fluoroscopy
subject: Paediatric
subject: Contrast agents
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1. Learn the uses and appropriate concentrations of contrast agents, and describe potential risks of the agents. 2. List the necessary equipment and understand the preparation for each fluoroscopic study. 3. Understand the views required for...
Genotypic distribution and hepatic fibrosis among HIV/HCV co-infected individuals in Southern China: a retrospective cross-sectional study
Creators: name: Wang, Charles
name: Tucker, Joseph
name: Lemon, Stanley
Publisher: name: BioMed Central
Year: 2015

description: Abstract Background End-stage liver disease and hepatocellular carcinoma due to hepatitis C virus (HCV) co-infection are increasingly common causes of death among HIV-infected individuals. However, there are few clinical investigations of HIV/HCV co-infected individuals from low and middle-income nations. Here, we compare the epidemiology of HCV-infected and HIV/HCV co-infected individuals in Southern China and examine hepatic fibrosis scores in co-infected individuals. Methods We conducted a retrospective cross-sectional study of treatment-naïve HIV/HCV co-infected and HCV mono-infected subjects. Bivariate and multivariate models were used to examine the association between demographics and HCV genotype. Among co-infected individuals, we also studied the relationship between fibrosis scores derived from non-invasive studies and HCV genotype. Results Data were collected from 175 HCV-infected individuals, including 89 (51 %) HIV/HCV co-infected individuals. HIV/HCV co-infection was correlated with intravenous drug use (AOR 46.25, p < 0.001) and not completing high school (AOR 17.39, p < 0.001) in a multivariate model. HIV/HCV co-infected individuals were more likely to be infected with HCV genotype 6a (p < 0.0001) or 3a (p < 0.023), whereas increased fibrosis (FIB-4 score) was associated with HCV genotype 3a infection (β 2.18, p < 0.001). Discussion Our results suggest that intravenous drug use is driving HIV/HCV co-infection in Southern China. While additional studies are needed, HCV genotype 6a is more common and genotype 3a appears to be associated with more severe hepatic fibrosis in co-infected individuals. Conclusions Future HIV/HCV co-infection research in China should focus on at risk populations, HCV testing uptake, and genotype-specific treatment.
title: A pictorial essay: Congenital malformations of the cranio-cervical junction
Creators: name: Nessej, Oumaima
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Congenital
subject: Diagnostic procedure
subject: MR
subject: CT
subject: Neuroradiology spine

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To familiarize the viewer with the imaging findings of congenital malformations of the cranio-cervical junction (CCJ) and discuss the place of MRI and CT scan in making the diagnosis of these...
title: Diagnosis and assessment of resectability of pancreatic cancer: the role of computed tomography
Creators: name: Mota, Alexandre
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Oncology
subject: Pancreas
subject: CT
subject: Diagnostic procedure
subject: Staging
subject: Cancer

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To illustrate computed tomography (CT) findings of pancreatic cancer important for the diagnosis. To review pancreatic cancer staging system and CT criteria that determine...
The role of the UPS in cystic fibrosis
Creators: name: Turnbull, Emma L
name: Rosser, Meredith FN
name: Cyr, Douglas
Publisher: name: BioMed Central Ltd
Year: 2007

description: Abstract CF is an inherited autosomal recessive disease whose lethality arises from malfunction of CFTR, a single chloride (Cl-) ion channel protein. CF patients harbor mutations in the CFTR gene that lead to misfolding of the resulting CFTR protein, rendering it inactive and mislocalized. Hundreds of CF-related mutations have been identified, many of which abrogate CFTR folding in the endoplasmic reticulum (ER). More than 70% of patients harbor the ΔF508 CFTR mutation that causes misfolding of the CFTR proteins. Consequently, mutant CFTR is unable to reach the apical plasma membrane of epithelial cells that line the lungs and gut, and is instead targeted for degradation by the UPS. Proteins located in both the cytoplasm and ER membrane are believed to identify misfolded CFTR for UPS-mediated degradation. The aberrantly folded CFTR protein then undergoes polyubiquitylation, carried out by an E1-E2-E3 ubiquitin ligase system, leading to degradation by the 26S proteasome. This ubiquitin-dependent loss of misfolded CFTR protein can be inhibited by the application of ‘corrector’ drugs that aid CFTR folding, shielding it from the UPS machinery. Corrector molecules elevate cellular CFTR protein levels by protecting the protein from degradation and aiding folding, promoting its maturation and localization to the apical plasma membrane. Combinatory application of corrector drugs with activator molecules that enhance CFTR Cl- ion channel activity offers significant potential for treatment of CF patients. Publication history: Republished from Current BioData's Targeted Proteins database (TPdb; http://www.targetedproteinsdb.com).
title: Hard to Digest!
Creators: name: Pai, Vivek
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Obstruction / Occlusion
subject: Neoplasia
subject: Motility
subject: Barium enema
subject: Barium meal
subject: Fluoroscopy
subject: Conventional radiography
subject: Colon
subject: Small bowel
subject: Stomach (incl. Oesophagus)

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The aim of this poster is to present a comprehensive pictorial review of barium studies done to evaluate pathologies of the gastro-intestinal tract . This poster is targeted to serve as reference material for resident radiologists in understanding...
Bouchea spathulata Torrey 1859
Creators: name: Pablo, Moroni
name: Nataly, O'Leary
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Verbenaceae
Bouchea
Bouchea spathulata

description: Bouchea spathulata Torrey (1859: 126)
 Type (lectotype, first-step designated by Moldenke 1940b: 127):— UNITED STATES OF AMERICA. Texas, Great Cañon of the Rio Grande near Mount Carmel, October 1852, C.C. Parry s.n. (NY!, two sheets; second-step lectotype, designated here NY [00103916!]; isolectotypes ISC No. 306329!, NY [00103917!], US 00118898!).
 Protologue citation:—“Great Cañon of the Rio Grande near Mount Carmel; October; Parry.”
 Notes:—Although Torrey (1859) did not indicate the herbarium which houses the type collection, it is well-known that his personal herbarium is kept at NY (Stafleu & Cowan 1986), as has been pointed out by Moldenke (1940b: 126). Moldenke’s statement is here interpreted according to the modern ICN (McNeill et al. 2012) as a lectotype designation. However, two sheets were found at NY, thus Moldenke’s statement can be considered as a first-step typification. In order to narrow Moldenke’s designation the most complete specimen is here selected as a second-step lectotype (Art. 9.17 of the ICN, McNeill et al. 2012, McNeill 2014). Two isolectotypes were also found, which are currently housed at herbaria ISC and US.
description: Published as part of Pablo, Moroni & Nataly, O'Leary, 2017, Typification of names in the genus Bouchea (Duranteae, Verbenaceae), pp. 211-216 in Phytotaxa 306 (3) on page 214, DOI: 10.11646/phytotaxa.306.3.3, http://zenodo.org/record/13696025
A case control study of environmental and occupational exposures associated with methicillin resistant Staphylococcus aureus nasal carriage in patients admitted to a rural tertiary care hospital in a high density swine region
Creators: name: Stewart, Jill
name: MacDonald, Pia DM
name: Wing, Steve
name: Richardson, David
name: Schinasi, Leah
Publisher: name: BioMed Central Ltd
Year: 2014

description: Abstract Background Distinct strains of methicillin resistant Staphylococcus aureus (MRSA) have been identified on livestock and livestock workers. Industrial food animal production may be an important environmental reservoir for human carriage of these pathogenic bacteria. The objective of this study was to investigate environmental and occupational exposures associated with nasal carriage of MRSA in patients hospitalized at Vidant Medical Center, a tertiary hospital serving a region with intensive livestock production in eastern North Carolina. Methods MRSA nasal carriage was identified via nasal swabs collected within 24 hours of hospital admission. MRSA carriers (cases) were gender and age matched to non-carriers (controls). Participants were interviewed about recent environmental and occupational exposures. Home addresses were geocoded and publicly available data were used to estimate the density of swine in residential census block groups of residence. Conditional logistic regression models were used to derive odds ratio (OR) estimates and 95% confidence intervals (CI). Presence of the scn gene in MRSA isolates was assessed. In addition, multi locus sequence typing (MLST) of the MRSA isolates was performed, and the Diversilab® system was used to match the isolates to USA pulsed field gel electrophoresis types. Results From July - December 2011, 117 cases and 119 controls were enrolled. A higher proportion of controls than cases were current workforce members (41.2% vs. 31.6%) Cases had a higher odds of living in census block groups with medium densities of swine (OR: 4.76, 95% CI: 1.36-16.69) and of reporting the ability to smell odor from a farm with animals when they were home (OR: 1.51, 95% CI: 0.80-2.86). Of 49 culture positive MRSA isolates, all were scn positive. Twenty-two isolates belonged to clonal complex 5. Conclusions Absence of livestock workers in this study precluded evaluation of occupational exposures. Higher odds of MRSA in medium swine density areas could reflect environmental exposure to swine or poultry.
title: The impact on Health-related Quality of Life in patients undergoing stereotactic breast biopsy versus open biopsy for diagnostic reasons.
Creators: name: Georgiou, Irene
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Neoplasia
subject: Vacuum assisted biopsy
subject: Mammography
subject: Breast

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Health-related Quality of Life (HRQoL) indices have been developed using several techniques in order to describe the outcome of a clinical process, or the health status of a population or a group of people. The data obtained from these studies can...
title: Thoracic emergencies in oncologic patients.
Creators: name: Madureira Cordeiro, Joana
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Metastases
subject: Cancer
subject: Diagnostic procedure
subject: Computer Applications-3D
subject: PET-CT
subject: CT
subject: Conventional radiography
subject: Thorax
subject: Oncology
subject: Emergency

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review the pathophysiology of the principal onco-thoracic emergencies in adults (eg central airway obstruction, esophagorespiratory fistula, pulmonary artery sarcoma vs pulmonary embolism, SVC syndrome, primary and metastic lung...
Nonequilibrium critical scaling from quantum thermodynamics
Creators: name: Bayat, Abolfazl
name: Apollaro, Tony J. G.
name: Paganelli, Simone
name: De Chiara, Gabriele
name: Johannesson, Henrik
name: Bose, Sougato
name: Sodano, Pasquale
Publisher: name: arXiv
Year: 2016
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The emerging field of quantum thermodynamics is contributing important results and insights into archetypal many-body problems, including quantum phase transitions. Still, the question whether out-of-equilibrium quantities, such as fluctuations of work, exhibit critical scaling after a sudden quench in a closed system has remained elusive. Here, we take a novel approach to the problem by studying a quench across an impurity quantum critical point. By performing density matrix renormalization group computations on the two-impurity Kondo model, we are able to establish that the irreversible work produced in a quench exhibits finite-size scaling at quantum criticality. This scaling faithfully predicts the equilibrium critical exponents for the crossover length and the order parameter of the model, and, moreover, implies a new exponent for the rescaled irreversible work. By connecting the irreversible work to the two-impurity spin correlation function, our findings can be tested experimentally.
description: 6 pages, 4 figures
title: Looking for changes in testicular echotexture: review of pathology with diffuse alteration of testicular echogenicity.
Creators: name: Atencia Ballesteros, Marta
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Genital / Reproductive system male
subject: Ultrasound
subject: eLearning
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: -Know the scrotal anatomy and normal testicular echotexture. -Review of the most frequent pathological disorders of the testicles with diffuse alteration in echogenicity. -Determine ultrasound findings that orient the differential...
Use of the Environment and Policy Evaluation and Observation as a Self-Report Instrument (EPAO-SR) to measure nutrition and physical activity environments in child care settings: validity and reliability evidence
Creators: name: McWilliams, Christina
name: Ward, Dianne
name: Hales, Derek
name: Mazzucca, Stephanie
Publisher: name: BioMed Central
Year: 2015

description: Abstract Background Early care and education (ECE) centers are important settings influencing young children’s diet and physical activity (PA) behaviors. To better understand their impact on diet and PA behaviors as well as to evaluate public health programs aimed at ECE settings, we developed and tested the Environment and Policy Assessment and Observation – Self-Report (EPAO-SR), a self-administered version of the previously validated, researcher-administered EPAO. Methods Development of the EPAO-SR instrument included modification of items from the EPAO, community advisory group and expert review, and cognitive interviews with center directors and classroom teachers. Reliability and validity data were collected across 4 days in 3–5 year old classrooms in 50 ECE centers in North Carolina. Center teachers and directors completed relevant portions of the EPAO-SR on multiple days according to a standardized protocol, and trained data collectors completed the EPAO for 4 days in the centers. Reliability and validity statistics calculated included percent agreement, kappa, correlation coefficients, coefficients of variation, deviations, mean differences, and intraclass correlation coefficients (ICC), depending on the response option of the item. Results Data demonstrated a range of reliability and validity evidence for the EPAO-SR instrument. Reporting from directors and classroom teachers was consistent and similar to the observational data. Items that produced strongest reliability and validity estimates included beverages served, outside time, and physical activity equipment, while items such as whole grains served and amount of teacher-led PA had lower reliability (observation and self-report) and validity estimates. To overcome lower reliability and validity estimates, some items need administration on multiple days. Conclusions This study demonstrated appropriate reliability and validity evidence for use of the EPAO-SR in the field. The self-administered EPAO-SR is an advancement of the measurement of ECE settings and can be used by researchers and practitioners to assess the nutrition and physical activity environments of ECE settings.
title: I spy with my little eye something...! Imaging of the acute orbital pathology in computed tomography.
Creators: name: Tapia Guerrero, Ana
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Trauma
subject: Inflammation
subject: Acute
subject: Computer Applications-Detection, diagnosis
subject: CT
subject: Eyes
subject: Emergency

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The purposes of thisexhibit are: Knowledge orbital anatomy. Review the indications for computed tomography (CT) study of the orbit. Optimize the study protocol. Show the most common acute orbital pathology in Emergency Radiology and their imaging...
Testing Predictions from Density Functional Theory at Finite Temperatures: $β_2$-Like Ground States in Co-Pt
Creators: name: Decolvenaere, Elizabeth
name: Gordon, Michael J.
name: Van der Ven, Anton
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We perform a critical assessment of the accuracy of DFT-based methods in predicting stable phases within the Co-Pt binary alloy. Statistical mechanical analysis applied to zero kelvin DFT predictions yields finite-temperature results that can be directly compared with experimental measurements. The predicted temperature-composition phase diagram is qualitatively incompatible with experimental observations, indicating that the predicted stability of long-period superstructures as ground states in the Co-Pt binary is incorrect. We also show that recently suggested methods to better align DFT and experiment via the hybrid functional HSE06 are unable to resolve the discrepancies in this system. Our results indicate a need for better verification of DFT based phase stability predictions, and highlight fundamental flaws in the ability of DFT to treat late 3$d$-5$d$ binary alloys.
description: 7 Pages, 3 Figures, Supplemental PDF included
Supplementary materials to Comparative Exercise Physiology manuscript CEP220044: Effect of gait on, and repeatability of, heart rate and heart rate variability measurements in exercising Warmblood dressage horses
Creators: name: Frippiat, T.
name: van Beckhoven, C.
name: van Gasselt, V.J.
name: Dugdale, A.
name: Vandeweerd, J.M.
Publisher: name: Brill Online
Year: 2023
Subjects: Veterinary anatomy and physiology

description: Heart rate variability (HRV) is a non-invasive measurement of the balance between the sympathetic and parasympathetic innervation to the myocardium. Used as an indicator of health, welfare and fitness level, its measurement during exercise has been suggested to be helpful in sport horses. The aim of this study was to assess the within-day and between-day repeatability of time-domain HRV measurements during exercise and to evaluate the effect of gait (as a factor of increasing exercise intensity) on HRV. Heart rate (HR), root mean square of successive differences (RMSSD) between normal heartbeats and the standard deviation of normal (R-R) intervals (SDNN) were assessed during a standardised exercise test (SET) on 5 successive days in a sample of 21 healthy Warmblood dressage horses. All variables showed good between-day repeatability (Spearman’s rank correlation coefficient), while only RMSSD showed reliable within-day repeatability (Wilcoxon signed-rank test). Increase of exercise intensity was significantly associated with increased HR and decreased RMSSD and SDNN, with a negative correlation between HR and the two HRV-measurements. HR and HRV values varied significantly with intensity of exercise (rest, walk, trot, canter and whole SET), though HRV at rest was not different to that at walk and HRV at trot was not different to that at canter. In conclusion, the results of this study support the use and show the repeatability of time-domain HRV-measurements during exercise in Warmblood dressage horses. Further investigation for use of HRV in other equestrian disciplines, levels and health status is warranted.
The relationship of oral health literacy with oral health-related quality of life in a multi-racial sample of low-income female caregivers
Creators: name: Lee, Jessica Y.
name: Divaris, Kimon
name: Vann, William
name: Baker, Diane
Publisher: name: BioMed Central Ltd
Year: 2011

description: Abstract Background To investigate the association between oral health literacy (OHL) and oral health-related quality of life (OHRQoL) and explore the racial differences therein among a low-income community-based group of female WIC participants. Methods Participants (N = 1,405) enrolled in the Carolina Oral Health Literacy (COHL) study completed the short form of the Oral Health Impact Profile Index (OHIP-14, a measure of OHRQoL) and REALD-30 (a word recognition literacy test). Socio-demographic and self-reported dental attendance data were collected via structured interviews. Severity (cumulative OHIP-14 score) and extent of impact (number of items reported fairly/very often) scores were calculated as measures of OHRQoL. OHL was assessed by the cumulative REALD-30 score. The association of OHL with OHRQoL was examined using descriptive and visual methods, and was quantified using Spearman's rho and zero-inflated negative binomial modeling. Results The study group included a substantial number of African Americans (AA = 41%) and American Indians (AI = 20%). The sample majority had a high school education or less and a mean age of 26.6 years. One-third of the participants reported at least one oral health impact. The OHIP-14 mean severity and extent scores were 10.6 [95% confidence limits (CL) = 10.0, 11.2] and 1.35 (95% CL = 1.21, 1.50), respectively. OHL scores were distributed normally with mean (standard deviation, SD) REALD-30 of 15.8 (5.3). OHL was weakly associated with OHRQoL: prevalence rho = -0.14 (95% CL = -0.20, -0.08); extent rho = -0.14 (95% CL = -0.19, -0.09); severity rho = -0.10 (95% CL = -0.16, -0.05). "Low" OHL (defined as < 13 REALD-30 score) was associated with worse OHRQoL, with increases in the prevalence of OHIP-14 impacts ranging from 11% for severity to 34% for extent. The inverse association of OHL with OHIP-14 impacts persisted in multivariate analysis: Problem Rate Ratio (PRR) = 0.91 (95% CL = 0.86, 0.98) for one SD change in OHL. Stratification by race revealed effect-measure modification: Whites--PRR = 1.01 (95% CL = 0.91, 1.11); AA--PRR = 0.86 (95% CL = 0.77, 0.96). Conclusions Although the inverse association between OHL and OHRQoL across the entire sample was weak, subjects in the "low" OHL group reported significantly more OHRQoL impacts versus those with higher literacy. Our findings indicate that the association between OHL and OHRQoL may be modified by race.