cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Fornace, nessuna traccia d’aloni di materia oscura
Creators: Maura Sandri
Publisher: name: Media Inaf
Year: 2022

I risultati di uno studio condotto sulle galassie nane del vicino ammasso della Fornace sfidano il modello cosmologico standard, suggerendo che tali galassie siano prive di aloni di materia oscura. Gli autori trovano invece un notevole accordo tra le osservazioni e le aspettative della Mond, o Dinamica newtoniana modificata. Lo studio è stato pubblicato su Monthly Notices of the Royal Astronomical Society
Centoventimila giovani stelle della porta accanto
Creators: Mario Guarcello
Publisher: name: Media Inaf
Year: 2022

Un team di ricercatori guidato dall’astrofisica Loredana Prisinzano dell’Inaf di Palermo, avvalendosi del catalogo Edr3 di Gaia, ha identificato 124440 protostelle con età inferiore ai 10 milioni di anni entro un raggio di 4500 anni luce dal Sole. Grazie a un algoritmo di unsupervised machine learning è stato possibile associarle a 676 ammassi stellari o regioni di formazione stellare
Abbagliati da Starlink? Uno studio ci svela quanto
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2022

Un team di studenti e docenti dell’Università dell’Arizona ha messo a punto un sensore per misurare la quantità di luce riflessa dai satelliti delle megacostellazioni in orbita bassa e lo ha usato per valutare in modo puntuale l’impatto di 61 dei piccoli satelliti di SpaceX. Ne parliamo con uno degli autori, il professor Roberto Furfaro, originario di Roccella Jonica, da 25 anni in Arizona
Regulatory principles in metabolism -Then and now
Creators: name: Fernandes Cruzat, Vinicius
Publisher: name: Torrens University Australia
Year: 2022
Subjects: Metabolic medicine

description: The importance of metabolic pathways for life and the nature of participating reactions have challenged physiologists and biochemists for over a hundred years. Eric Arthur Newsholme contributed many original hypotheses and concepts to the field of metabolic regulation, demonstrating that metabolic pathways have a fundamental thermodynamic structure and that near identical regulatory mechanisms exist in multiple species across the animal kingdom. His work at Oxford University from the 1970s to 1990s was groundbreaking and led to better understanding of development and demise across the lifespan as well as the basis of metabolic disruption responsible for the development of obesity, diabetes and many other conditions. In the present review we describe some of the original work of Eric Newsholme, its relevance to metabolic homoeostasis and disease and application to present state-of-The-Art studies, which generate substantial amounts of data that are extremely difficult to interpret without a fundamental understanding of regulatory principles. Eric's work is a classical example of how one can unravel very complex problems by considering regulation from a cell, tissue and whole body perspective, thus bringing together metabolic biochemistry, physiology and pathophysiology, opening new avenues that now drive discovery decades thereafter.
title: Brief
Creators: name: Binter, Josef
Year: 2017

description: 3 Beilagen von insgesamt 5 Blättern und 6 Seiten: 1. Programmentwurf für das Internationale Symposium "Friedensforschung und Friedenspolitik: Aufgaben und Chancen für Österreich", Bad Tatzmannsdorf 26.-27. November 1983, 2. Kurzbeschreibung Österreichisches Institut für Friedensforschung, 3. Veranstaltungsplan 1983 und Programmvorschau 1984.
description: Typoskript mit Unterschrift, 7 Blätter, 8 Seiten
title: Use of CT and MRI for occult neck of femur fractures: the Austin Health experience
Creators: name: Lamanna, Anthony
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2018
Subjects: subject: Bones
subject: Emergency
subject: Musculoskeletal bone
subject: CT
subject: MR
subject: Plain radiographic studies
subject: Audit and standards
subject: Diagnostic procedure
subject: Acute
subject: Geriatrics
subject: Osteoporosis

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Neck of femur fractures (NOF) are common and serious injuries in the elderly. To decrease morbidity and mortality, timely and accurate diagnosis of hip fractures is required [1]. When a NOF is suspected but not visible on a plain x-ray, guidelines...
Body, Name, Voice: Chanel Miller’s Self-Reclamation after Sexual Assault Through Literary Choices in Know My Name
Creators: name: Weisel, Hailey
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: Chanel Miller
Sexual Assault
Literary Choices
#MeToo
Memoir

description: This thesis exploration will examine how Chanel Miller's literary choices in Know My Name allow her to stitch together the pieces of her identity that were brutally ripped apart during and following her assault. This memoir is Chanel Miller's opportunity to reclaim the triad of things taken from her: her body, her name, and her voice. Entering the #MeToo memoir genre allows Chanel to accumulate readers who intimately understand her story and can advocate for Chanel and other survivors of abuse, which is an integral shift from the trial where Chanel was shamed and belittled. Through literary choices such as the omission of the defense attorney’s and judge’s names and the emphatic repetition of the first-person pronoun, Chanel stitches back together her body, her name, and her voice, which Brock Turner and the judicial system attempted to unravel altogether.
Clinical Findings and Pain Symptoms as Potential Risk Factors for Chronic TMD: Descriptive Data and Empirically Identified Domains from the OPPERA Case-Control Study
Creators: name: Gonzalez, Yoly
name: Greenspan, Joel D.
name: Knott, Charles
name: Ribeiro-Dasilva, Margarete
name: Maixner, William
name: Slade, Gary
name: Lim, Pei-Feng
name: Mulkey, Flora
name: Gordon, Sharon
name: Fillingim, Roger B.
name: Gremillion, Henry
name: Ohrbach, Richard
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Clinical characteristics might be associated with temporomandibular disorders (TMD) because they are antecedent risk factors that increase the likelihood of a healthy person developing the condition or because they represent signs or symptoms of either subclinical or overt TMD. In this baseline case-control study of the multisite Orofacial Pain: Prospective Evaluation and Risk Assessment (OPPERA) project, 1,633 controls and 185 cases with chronic, painful TMD completed questionnaires and received clinical examinations. Odds ratios measuring association between each clinical factor and TMD were computed, with adjustment for study-site as well as age, sex, and race/ethnicity. Compared to controls, TMD cases reported more trauma, greater parafunction, more headaches and other pain disorders, more functional limitation in using the jaw, more nonpain symptoms in the facial area, more temporomandibular joint noises and jaw locking, more neural or sensory medical conditions, and worse overall medical status. They also exhibited on examination reduced jaw mobility, more joint noises, and a greater number of painful masticatory, cervical, and body muscles upon palpation. The results indicated that TMD cases differ substantially from controls across almost all variables assessed. Future analyses of follow-up data will determine whether these clinical characteristics predict increased risk for developing first-onset pain-related TMD
Coherent neutrino-nucleus scattering detection with a CsI[Na] scintillator at the SNS spallation source
Creators: name: Collar, J. I.
name: Fields, N. E.
name: Fuller, E.
name: Hai, M.
name: Hossbach, T. W.
name: Orrell, J. L.
name: Perumpilly, G.
name: Scholz, B.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We study the possibility of using CsI[Na] scintillators as an advantageous target for the detection of coherent elastic neutrino-nucleus scattering (CENNS), using the neutrino emissions from the SNS spallation source at Oak Ridge National Laboratory. The response of this material to low-energy nuclear recoils like those expected from this process is characterized. Backgrounds are studied using a 2 kg low-background prototype crystal in a dedicated radiation shield. The conclusion is that a planned 14 kg detector should measure approximately 550 CENNS events per year above a demonstrated $\sim7$ keVnr low-energy threshold, with a signal-to-background ratio sufficient for a first measurement of the CENNS cross-section. The cross-section for the $^{208}$Pb($ν_{e},e^{-}$)$^{208}$Bi reaction, of interest for future supernova neutrino detection, can be simultaneously obtained.
description: v2: minor corrections
SpaceX, decollata la prima sonda lunare coreana
Creators: Maura Sandri
Publisher: name: Media Inaf
Year: 2022

Un Falcon 9 con a bordo Danuri, la prima sonda spaziale lunare della Corea del Sud, è decollato da Cape Canaveral alle 01:08 ora italiana di questa notte, aprendo un nuovo capitolo nel programma spaziale del paese. Sempre in questi giorni, è stato ritrovato un pezzo del Dragon utilizzato durante il ritorno della missione Crew-1 nel maggio 2021, piombato in un campo australiano un anno dopo
Disruptive mRNA folding increases translational efficiency of catechol-O-methyltransferase variant
Creators: name: Dokholyan, N.
name: Gauthier, J.
name: Shabalina, S.
name: Diatchenko, L.
name: Tsao, D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Catechol-O-methyltransferase (COMT) is a major enzyme controlling catecholamine levels that plays a central role in cognition, affective mood and pain perception. There are three common COMT haplotypes in the human population reported to have functional effects, divergent in two synonymous and one nonsynonymous position. We demonstrate that one of the haplotypes, carrying the non-synonymous variation known to code for a less stable protein, exhibits increased protein expression in vitro. This increased protein expression, which would compensate for lower protein stability, is solely produced by a synonymous variation (C166T) situated within the haplotype and located in the 5′ region of the RNA transcript. Based on mRNA secondary structure predictions, we suggest that structural destabilization near the start codon caused by the T allele could be related to the observed increase in COMT expression. Our folding simulations of the tertiary mRNA structures demonstrate that destabilization by the T allele lowers the folding transition barrier, thus decreasing the probability of occupying its native state. These data suggest a novel structural mechanism whereby functional synonymous variations near the translation initiation codon affect the translation efficiency via entropy-driven changes in mRNA dynamics and present another example of stable compensatory genetic variations in the human population.
Radial penetration of flux surface shaping in tokamaks
Creators: name: Ball, Justin
name: Parra, Felix I.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Using analytic calculations, the effects of the edge flux surface shape and the toroidal current profile on the penetration of flux surface shaping are investigated in a tokamak. It is shown that the penetration of shaping is determined by the poloidal variation of the poloidal magnetic field on the surface. This fact is used to investigate how different flux surface shapes penetrate from the edge. Then, a technique to separate the effects of magnetic pressure and tension in the Grad-Shafranov equation is presented and used to calculate radial profiles of strong elongation for nearly constant current profiles. Lastly, it is shown that more hollow toroidal current profiles are significantly better at conveying shaping from the edge to the core.
description: 11 pages, 13 figures
title: Giant Breast Masses – A Pictorial Essay
Creators: name: Chitty, Christopher
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2018
Subjects: subject: Diagnostic procedure
subject: Ultrasound
subject: Mammography
subject: Breast
subject: Education and training

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To enable the reader to recognize the radiological features related to a spectrum of giant breast...
Breve e potentissimo, un lampo gamma per Alma
Creators: Federico Di Giacomo
Publisher: name: Media Inaf
Year: 2022

Osservato per la prima volta alle lunghezze d’onda millimetriche, grazie alla sensibilità delle antenne di Alma, il bagliore di un lampo gamma corto, prodotto verosimilmente dalla fusione di una stella di neutroni con un’altra stella. Il team che ha condotto lo studio ha confermato che Grb 211106A – questo il suo nome – è uno fra i più brevi ed energetici gamma ray burst mai osservati
Oscillating Decay Rate in Electron Capture and the Neutrino Mass Difference
Creators: name: Peshkin, Murray
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Reported oscillations in the rate of decay of certain ions by K-electron capture have raised questions about whether and how such oscillations can arise in quantum mechanical theory and whether they can measure the neutrino mass difference. Here I show that simple principles of quantum mechanics answer some questions and clarify what must be done theoretically or experimentally to answer some others. The principal result is that quantum mechanics does allow mass-difference-dependent oscillations in principle, but it imposes conditions not obeyed by the approximate dynamical models that have been put forth up to now. What needs to be done experimentally and theoretically is discussed.
description: 8 pages. This version differs from arXiv1409.0037 primarily in that the relevant dynamical variables of the ion beam cooling systems and the detection apparatus are taken into account. The results are the same
Regulation of SIRT1 in aging: Roles in mitochondrial function and biogenesis
Creators: name: Fernandes Cruzat, Vinicius
Publisher: name: Torrens University Australia
Year: 2022
Subjects: Microbial genetics

description: Aging is a degenerative process associated with cumulative damage, which leads to cellular dysfunction, tissue failure, and disorders of body function. Silent information regulator-1, also known as sirtuin 1 (SIRT1), has been reported to be involved in the regulation of various important biological processes, including inflammation, mitochondrial biogenesis, as well as cell senescence and consequent aging. The level of SIRT1 is decreased in both transcriptional and postranscriptional conditions during aging, accompanied by attenuated mitochondrial biogenesis, an important component of aging-related diseases. Over the last decade, extensive studies have demonstrated that SIRT1 can activate several transcriptional factors, such as peroxisome proliferator activated receptor γ co-activator 1α (PGC-1α) and hypoxia-inducible factor 1α (HIF-1α) resulting in ameliorated mitochondria biogenesis and extended life span. In this review, we focus on the molecular regulation of SIRT1 and its role in mitochondrial biogenesis during in the context of aging and aging-related diseases.
Pain Sensitivity Risk Factors for Chronic TMD: Descriptive Data and Empirically Identified Domains from the OPPERA Case Control Study
Creators: name: Maixner, William
name: Knott, Charlie
name: Rothwell, Rebecca
name: Slade, Gary D.
name: Dubner, Ronald
name: Mulkey, Flora
name: Ohrbach, Richard
name: Bair, Eric
name: Fillingim, Roger B.
name: Greenspan, Joel D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Many studies report that people with temporomandibular disorders (TMD) are more sensitive to experimental pain stimuli than TMD-free controls. Such differences in sensitivity are observed in remote body sites as well as in the orofacial region, suggesting a generalized upregulation of nociceptive processing in TMD cases. This large case-control study of 185 adults with TMD and 1,633 TMD-free controls measured sensitivity to painful pressure, mechanical cutaneous, and heat stimuli, using multiple testing protocols. Based on an unprecedented 36 experimental pain measures, 28 showed statistically significantly greater pain sensitivity in TMD cases than controls. The largest effects were seen for pressure pain thresholds at multiple body sites and cutaneous mechanical pain threshold. The other mechanical cutaneous pain measures and many of the heat pain measures showed significant differences, but with lesser effect sizes. Principal component analysis (PCA) of the pain measures derived from 1,633 controls identified five components labeled: (1) heat pain ratings, (2) heat pain aftersensations and tolerance, (3) mechanical cutaneous pain sensitivity, (4) pressure pain thresholds, and (5) heat pain temporal summation. These results demonstrate that, compared to TMD-free controls, chronic TMD cases are more sensitive to many experimental noxious stimuli at extra-cranial body sites, and provides for the first time the ability to directly compare the case-control effect sizes of a wide range of pain sensitivity measures.
Lower Bounds for Tropical Circuits and Dynamic Programs
Creators: name: Jukna, Stasys
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computational Complexity (cs.CC)
subject: FOS: Computer and information sciences

description: Tropical circuits are circuits with Min and Plus, or Max and Plus operations as gates. Their importance stems from their intimate relation to dynamic programming algorithms. The power of tropical circuits lies somewhere between that of monotone boolean circuits and monotone arithmetic circuits. In this paper we present some lower bounds arguments for tropical circuits, and hence, for dynamic programs.
description: Corrected reduction to arithmetic circuits (holds only for multilinear polynomials, now Sect. 4). Solved Open Problem 3 about Min/Max gaps (now Lemma 10). Added lower bounds for the depth of tropical circuits (Sect. 15)
Potential Autonomic Risk Factors for Chronic TMD: Descriptive Data and Empirically Identified Domains from the OPPERA Case-Control Study
Creators: name: Fillingim, Roger B.
name: Ohrbach, Richard
name: Bair, Eric
name: Diatchenko, Luda
name: Miller, Vanessa
name: Slade, Gary D.
name: Knott, Charles
name: Mulkey, Flora
name: Maixner, William
name: Greenspan, Joel D.
name: Dubner, Ronald
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Several case-control studies have been conducted that examine the association between autonomic variables and persistent pain conditions; however, there is a surprising dearth of published studies in this area that have focused on temporomandibular disorders (TMD). The current study presents autonomic findings from the baseline case-control study of the OPPERA (Orofacial Pain: Prospective Evaluation and Risk Assessment) cooperative agreement. Measures of arterial blood pressure, heart rate, heart rate variability, and indirect measures of baroreflex sensitivity were assessed at rest and in response to a physical (orthostatic) and psychological (Stroop) stressors in 1633 TMD-free controls and 185 TMD cases. In bivariate and demographically adjusted analyses, greater odds of TMD case status were associated with elevated heart rates, reduced heart rate variability, and reduced surrogate measures of baroreflex sensitivity across all experimental procedures. Principal component analysis was undertaken to identify latent constructs revealing five components. These findings provide evidence of associations between autonomic factors and TMD. Future prospective analyses in the OPPERA cohort will determine if the presence of these autonomic factors predicts increased risk for developing new onset TMD.
Potential Genetic Risk Factors for Chronic TMD: Genetic Associations from the OPPERA Case Control Study
Creators: name: Maixner, Dylan W.
name: Slade, Gary D.
name: Gibson, Dustin G.
name: Smith, Shad B.
name: Greenspan, Joel D.
name: Knott, Charles
name: Ohrbach, Richard
name: Weir, Bruce S.
name: Dubner, Ronald
name: Diatchenko, Luda
name: Maixner, William
name: Zaykin, Dmitri V.
name: Fillingim, Roger B.
name: Bair, Eric
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Genetic factors play a role in the etiology of persistent pain conditions, putatively by modulating underlying processes such as nociceptive sensitivity, psychological well-being, inflammation, and autonomic response. However, to date, only a few genes have been associated with temporomandibular disorders (TMD). This study evaluated 358 genes involved in pain processes, comparing allelic frequencies between 166 cases with chronic TMD and 1442 controls enrolled in the OPPERA (Orofacial Pain: Prospective Evaluation and Risk Assessment) study cooperative agreement. To enhance statistical power, 182 TMD cases and 170 controls from a similar study were included in the analysis. Genotyping was performed using the Pain Research Panel, an Affymetrix gene chip representing 3295 single nucleotide polymorphisms, including ancestry-informative markers that were used to adjust for population stratification. Adjusted associations between genetic markers and TMD case status were evaluated using logistic regression. The OPPERA findings provided evidence supporting previously-reported associations between TMD and two genes: HTR2A and COMT. Other genes were revealed as potential new genetic risk factors for TMD, including NR3C1, CAMK4, CHRM2, IFRD1, and GRK5. While these findings need to be replicated in independent cohorts, the genes potentially represent important markers of risk for TMD and they identify potential targets for therapeutic intervention.
title: A review of clinical practice from an urban emergency centre - are we imaging pyelonephritis appropriately?
Creators: name: Chacko, Amit
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2018
Subjects: subject: Urinary Tract / Bladder
subject: Kidney
subject: Emergency
subject: CT
subject: Ultrasound
subject: Radiation safety
subject: Health policy and practice
subject: Education and training

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Pyelonephritis and urinary tract infections are increasingly common in the community, accounting for 12% of emergency presentations and 1.2% of general practice consultations.1,2 The role of diagnostic imaging in patients with suspected...
Lucy, lo spicchio del pannello difettoso si è ridotto
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2022

Grazie a una manovra ingegnosa e mai provata prima, i responsabili della missione Lucy della Nasa – una sonda in viaggio verso gli asteroidi troiani di Giove – sono riusciti a dispiegare a sufficienza, seppur ancora non del tutto, il pannello solare che si era inceppato poche ore dopo il lancio, avvenuto nell’ottobre del 2021
Varying-Alpha and K-Essence
Creators: name: Graham, Alexander A. H.
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We introduce a model which allows the fine structure constant (alpha) to vary throughout space and time due to a coupling to a scalar field with a non-canonical kinetic structure. This provided a new extension of the Bekenstein-Sandvik-Barrow-Magueijo model of alpha variations. The background cosmology is studied in detail using dynamical systems techniques for a scalar field of ghost condensate type. We show generically that if the kinetic terms are chosen to allow an accelerated late-time attractor for the expansion scale factor then alpha will not asymptote to a constant at late times.
description: 14 pages, 3 figures. v2: typos corrected, references added and some additional comments. Matches published version
Potential Psychosocial Risk Factors for Chronic TMD: Descriptive Data and Empirically Identified Domains from the OPPERA Case-Control Study
Creators: name: Ohrbach, Richard
name: Maixner, William
name: Greenspan, Joel D.
name: Dubner, Ronald
name: Fillingim, Roger B.
name: Baraian, Cristina
name: Slade, Gary D.
name: Knott, Charles
name: Bair, Eric
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Case-control studies have consistently associated psychosocial factors with chronic pain in general, and with temporomandibular disorders (TMD) specifically. Moreover, a handful of prospective studies suggest that pre-existing psychosocial characteristics represent risk factors for new onset TMD. The current study presents psychosocial findings from the baseline case-control study of the Orofacial Pain Prospective Evaluation and Risk Assessment (OPPERA) cooperative agreement. For this study, 1,633 TMD-free controls and 185 TMD cases completed a battery of psychosocial instruments assessing general psychosocial adjustment and personality, affective distress, psychosocial stress, somatic awareness, and pain coping and catastrophizing. In bivariate and demographically-adjusted analyses, odds of TMD were associated with higher levels of psychosocial symptoms, affective distress, somatic awareness, and pain catastrophizing. Among controls, significant gender and ethnic group differences in psychosocial measures were observed, consistent with previous findings. Principal component analysis was undertaken to identify latent constructs revealing four components: stress and negative affectivity, global psychosocial symptoms, passive pain coping, and active pain coping. These findings provide further evidence of associations between psychosocial factors and TMD. Future prospective analyses in the OPPERA cohort will determine if the premorbid presence of these psychosocial factors predicts increased risk for developing new-onset TMD.
Nuova luce sulla galassia Ruota di Carro con Jwst
Creators: Laura Leonardi
Publisher: name: Media Inaf
Year: 2022

Il potente sguardo a infrarossi del telescopio spaziale James Webb della Nasa ci regala un'immagine dettagliata della galassia dalla rara morfologia ad anello Eso 350-40, nota come galassia Ruota di Carro, facendo nuova luce sulla sua formazione ed evoluzione
La Nasa finanzia un robot chirurgo spaziale
Creators: Valentina Guglielmo
Publisher: name: Media Inaf
Year: 2022

Centomila dollari e circa di due anni di tempo per ottimizzare e preparare il prototipo di un robot chirurgo al volo spaziale. Il progetto è finanziato dall’agenzia spaziale statunitense e guidato da ricercatori dell’università del Nebraska e della startup Virtual Incision
Can a Single High-energy Neutrino from Gamma-ray Bursts be a Discovery?
Creators: name: Bartos, Imre
name: Marka, Szabolcs
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Current emission models of GeV-PeV neutrinos from gamma-ray bursts (GRBs) predict a neutrino flux with $\ll 1$ detected neutrinos per GRB with kilometer-scale neutrino observatories. The detection of this flux will require the stacking of data from a large number of GRBs, leading to an increased background rate, decreasing the significance of a single neutrino detection. We show that utilizing the temporal correlation between the expected gamma-ray and neutrino fluxes, one can significantly improve the neutrino signal-to-noise ratio. We describe how this temporal correlation can be used. Using realistic GRB and atmospheric neutrino fluxes and incorporating temporal, spectral and directional information, we estimate the probability of a single detected GRB-neutrino being a 5$σ$ discovery.
description: 5 pages, 2 figures. Accepted to PRD Rapid Communication
Study Methods, Recruitment, Sociodemographic Findings, and Demographic Representativeness in the OPPERA Study
Creators: name: By, Kunthel
name: Dubner, Ron
name: Mulkey, Flora
name: Gonzalez, Yoly
name: Diatchenko, Luda
name: Bair, Eric
name: Gordon, Sharon
name: Rothwell, Rebecca
name: Miller, Vanessa
name: Lim, Pei Feng
name: Dampier, Dawn
name: Maixner, William
name: Baraian, Cristina
name: Ohrbach, Richard
name: Reynolds, Maria
name: Greenspan, Joel D.
name: Slade, Gary D.
name: Knott, Charles
name: Fillingim, Roger B.
name: Ribeiro-Dasilva, Margarete
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: This paper describes methods used in the project “Orofacial Pain Prospective Evaluation and Risk Assessment” (OPPERA) and evaluates socio-demographic characteristics associated with temporomandibular disorders (TMD) in the OPPERA case-control study. Representativeness was investigated by comparing socio-demographic profiles of OPPERA participants with population census profiles of counties near study sites and by comparing age- and gender-associations with TMD in OPPERA and the 2007-09 US National Health Interview Survey. Volunteers aged 18-44 years were recruited at four US study sites: 3,263 people without TMD were enrolled into the prospective cohort study; 1,633 of them were selected as controls for the baseline case-control study. Cases were 185 volunteers with examiner-classified TMD. Distributions of some demographic characteristics among OPPERA participants differed from census profiles, although there was less difference in socio-economic profiles. Odds of TMD was associated with greater age in this 18-44 year range; females had three times the odds of TMD as males; and relative to non-Hispanic-Whites, other racial groups had one-fifth the odds of TMD. Age- and gender-associations with chronic TMD were strikingly similar to associations observed in the US population. Assessments of representativeness in this demographically diverse group of community volunteers suggest that OPPERA case-control findings have good internal validity.
title: Quality improvement initiatives to reduce deep vein thrombosis associated with peripherally inserted central catheters in adults
Creators: name: Chacko, Amit
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2018
Subjects: subject: Interventional vascular
subject: Oncology
subject: Ultrasound
subject: Plain radiographic studies
subject: Catheters
subject: Complications
subject: Quality assurance
subject: Embolism / Thrombosis

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: The use of PICCs has increased rapidly in hospitalised settings over the past few years. This is primarily due to the cost-effectiveness, ease of insertion and perceived safety of insertion of PICCs.1,3,5 Despite these advantages, there is...
Pigment epithelium-derived factor (PEDF) regulates metabolism and insulin secretion from a clonal rat pancreatic beta cell line BRIN-BD11 and mouse islets
Creators: name: Fernandes Cruzat, Vinicius
Publisher: name: Torrens University Australia
Year: 2022
Subjects: Endocrinology

description: Pigment epithelium-derived factor (PEDF) is a multifunctional glycoprotein, associated with lipid catabolism and insulin resistance. In the present study, PEDF increased chronic and acute insulin secretion in a clonal rat β-cell line BRIN-BD11, without alteration of glucose consumption. PEDF also stimulated insulin secretion from primary mouse islets. Seahorse flux analysis demonstrated that PEDF did not change mitochondrial respiration and glycolytic function. The cytosolic presence of the putative PEDF receptor - adipose triglyceride lipase (ATGL) - was identified, and ATGL associated stimulation of glycerol release was robustly enhanced by PEDF, while intracellular ATP levels increased. Addition of palmitate or ex vivo stimulation with inflammatory mediators induced β-cell dysfunction, effects not altered by the addition of PEDF. In conclusion, PEDF increased insulin secretion in BRIN-BD11 and islet cells, but had no impact on glucose metabolism. Thus elevated lipolysis and enhanced fatty acid availability may impact insulin secretion following PEDF receptor (ATGL) stimulation.
title: Brief von Gottfried Bombach an Kurt Rothschild
Creators: name: Bombach, Gottfried
Year: 2017

description: Grußworte mit Unterschriften der TeilnehmerInnen des Ottobeuren-Seminars.
description: Ansichtskarte mit Bild von Hotel Hirsch und Kirche, Rückseite beschrieben
MooringSense Project  - WP4 – Smart Sensor HW/SW Design Description
Creators: name: Fundación Centro Tecnológico de Componentes
Publisher: name: Zenodo
Year: 2023

description: Since 2014, EERA JP Wind has been organising yearly events in Amsterdam, often in collaboration with the industry platform ETIPWind and the SETPlan Implementation Working Group on offshore wind. The Wind Innovation Forum aims for knowledge exchange, network opportunities, collaboration opportunities and inspiration for new research topics. It aims on R&I priorities and technology development visions.Presentation of CTC: "Technical solution for the GNSS Smart Sensor for the structural health monitoring of the FOWT mooring lines"
This article presents technical solution of a low-cost smart sensor for FOWT motion monitoring that uses GNSS as a main driver for enhancing the accuracy in positioning. Development of the smart sensor forms a part of the MooringSense project which aims reduction of the operational costs through the development of an efficient risk-based integrity management strategy for mooring systems based on an affordable and reliable real-time monitoring technology.
The technological objectives of GNSS Smart Sensor design is to develop the positioning and orientation system using the disruptive GNSS receiver technology, operating over multiple frequency bands (i.e. E1, E2 and E5 from Galileo), and combining signals from different constellations of navigation satellites (GPS, Galileo, GLONAS, BeiDou). These receivers supported by advanced algorithm of Precise Point Positioning (PPP) integrated inside the powerful processing unit, fused together with the Inertial measurement unit, improve global positioning of the FOWT, providing centimeter level accuracy. The major technological achievement of the GNSS smart sensors development is increased accuracy in position determination operating in real time; very low power consumption; reduced size and weight; immunity to interferences produced by the operating environment and the advanced operability under severe environmental environment conditions.
Detailed description about the system electronics hardware, software, interfaces and operational modes and communication are presented in this article. Hardware development level such as the tests provided during the project, will raise this system towards TRL6, which will correspond to the prototype demonstration in a relevant environment.
title: Rapid MRI Brain Sequences for Ischaemic Stroke
Creators: name: Lee, Siobhan
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2018
Subjects: subject: Ischaemia / Infarction
subject: Imaging sequences
subject: MR
subject: Neuroradiology brain
subject: CNS

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To review the use of Siemens GOBrain rapid MRI sequence at the Calvary Mater Hospital (CMH) in Newcastle, targeted at detecting acute ischaemic cerebrovascular accident (CVA) using diffusion-weighted imaging (DWI). This incorporated assessment of:...
Acute Severe Pain Is a Common Consequence of Sexual Assault
Creators: name: Collette, Renee
name: Soward, April C.
name: Rauch, Sheila A.M.
name: Liberzon, Israel
name: Holbrook, Debra
name: Rossi, Catherine
name: Wheeler, Rebecca
name: McLean, Samuel A.
name: Ballina, Lauren E.
name: Rotolo, Suzanne
name: Casto, Terry
name: Foley, Kelly A.
name: Goodman, Elizabeth
name: Batts, Jayne
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Sexual assault (SA) is common, but the epidemiology of acute pain after SA has not previously been reported. We evaluated the severity and distribution of pain symptoms in the early aftermath of SA among women receiving sexual assault nurse examiner (SANE) care, and the treatment of pain by SANE nurses. Severe pain (≥7 on a 0–10 numeric rating scale) was reported by 53/83 women sexual assault survivors (64% [95% CI, 53%–74%]) at the time of SANE evaluation and 43/83 women (52% [95% CI, 41%–63%]) one week later. Pain in four or more body regions was reported by 44/83 women (53% [95% CI, 42%–64%]) at the time of initial evaluation and 49/83 women (59% [95% CI, 48%–70%]) at one week follow-up. Among survivors with severe pain at the time of initial post-assault evaluation, only 7/53 (13% [95% CI, 6%–26%]) received any pain medication at the time of initial SANE treatment. These findings suggest that pain is common in SA survivors in the early post-assault period, but rarely treated.
Excess Risk of Temporomandibular Disorder Associated With Cigarette Smoking in Young Adults
Creators: name: Diatchenko, Luda
name: Nackley, Andrea G.
name: By, Kunthel
name: Slade, Gary D.
name: Maixner, William
name: Miller, Vanessa E.
name: Sanders, Anne E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Evidence suggests that the effect of cigarette smoking on chronic pain is stronger in younger than older adults. This case control study investigated whether age modified an effect of smoking on temporomandibular disorder (TMD) in 299 females aged 18–60 years. It also investigated the extent to which this relationship was explained by psychological profile, inflammatory response and allergy. Cases were defined using the Research Diagnostic Criteria for Temporomandibular Disorders based on clinical examination. Psychological profile was evaluated using standardized instruments. Inflammatory response was evaluated with 11 cytokines isolated in plasma. History of allergy conditions was self-reported. Odds ratios (OR) for the effect of smoking were calculated using binary logistic regression. Stratified analyses and the likelihood ratio test examined effect modification by smoking. Compared to non-smokers, ever smokers aged <30 years had higher odds of TMD (OR =4.14, 95% CI: 1.57, 11.35) than older adults (OR =1.23, 95% CI: 0.55, 2.78) (P (effect modification) =0.038). Adjustment for psychological profile, cytokines and history of allergy-like conditions attenuated the effect by 45% to statistical non-significance. The main finding was reproduced with secondary analyses of two nationally-representative surveys of adults conducted in the U.S. and Australia.
title: Imaging of the Patellofemoral Joint: A Pictorial Essay
Creators: name: Jurevics, Richard
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2018
Subjects: subject: Musculoskeletal bone
subject: Musculoskeletal joint
subject: Musculoskeletal soft tissue
subject: Plain radiographic studies
subject: Ultrasound
subject: MR
subject: Education
subject: Normal variants
subject: Diagnostic procedure
subject: Trauma
subject: Inflammation
subject: Oedema

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: It is intended to meet the following learning objectives: to provide a list of some of the most common clinically significant pathologies affecting the patellofemoral joint, to show the imaging modality that was able to satisfactorily demonstrate...
Relationship Between Temporomandibular Disorders, Widespread Palpation Tenderness, and Multiple Pain Conditions: A Case-Control Study
Creators: name: Slade, Gary
name: Diatchenko, Luda
name: Chen, Hong
name: Miller, Vanessa
name: Maixner, William
name: Lim, Pei Feng
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The multiple bodily pain conditions in temporomandibular disorders (TMD) have been associated with generalized alterations in pain processing. The purpose of this study was to examine the relationship between the presence of widespread body palpation tenderness (WPT) and the likelihood of multiple comorbid pain conditions in TMD patients and controls. This case-control study was conducted in 76 TMD subjects with WPT, 83 TMD subjects without WPT, and 181 non-TMD matched control subjects. The study population was also characterized for clinical pain, experimental pain sensitivity, and related psychological phenotypes. Results showed that (1) TMD subjects reported an average of 1.7 comorbid pain conditions compared to 0.3 reported by the control subjects (p<0.001); (2) Compared to control subjects, the odds ratio (OR) for multiple comorbid pain conditions is higher for TMD subjects with WPT [OR 8.4 (95% CI 3.1–22.8) for TMD with WPT versus OR 3.3 (95% CI 1.3–8.4) for TMD without WPT]; (3) TMD subjects with WPT presented with reduced pressure pain thresholds (PPTs) in both cranial and extra-cranial regions compared to TMD subjects without WPT; and (4) TMD subjects with WPT reported increased somatic symptoms. These findings suggest that pain assessment outside of the orofacial region may prove valuable for the classification, diagnosis, and management of TMD patients.
I resti dell’approdo di Perseverance su Marte
Creators: Maura Sandri
Publisher: name: Media Inaf
Year: 2022

Quando Perseverance è arrivato su Marte, durante la fase conosciuta come Edl – acronimo di Entry, Descent, and Landing – ha “perso pezzi” che si sono distribuiti in superficie, a distanza di sicurezza dal rover. Parte di quell'hardware è stato successivamente ripreso, sia da Perseverance che da Ingenuity. Eccovi una carrellata di immagini dei detriti che si possono trovare sul suolo marziano
Reliability and Reproducibility of Novel Methodology for Assessment of Pressure Pain Sensitivity in Pelvis
Creators: name: Bair, Eric
name: Essick, Greg
name: Gracely, Richard
name: Goyal, Vinita
name: Maixner, William
name: Zolnoun, Denniz
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Vestibulodynia, the most common type of chronic vulvovaginal pain, impairs the psychological, physical health of nearly 10% of women at some point in their lifetime. The aim of this investigation was to establish reliable standardized methodologies for assessment of pain sensitivity in vulvar mucosa and pelvic musculature. We enrolled 34 women with vestibulodynia and 21 pain-free controls. The participants underwent a nuanced exam that consisted of palpation of precisely located vulvar mucosal and pelvic muscle sites. These measurements remained highly stable when participants were reexamined after two weeks, with high within-examiner correlation. Vestibulodynia patients reported greater sensitivity than pain-free controls at the majority of examination sites, particularly at mucosal sites on the lower vestibule. The pain threshold measures at the lower mucosal sites were also associated with the participants’ self-reported pain levels during intercourse. These mucosal pain threshold measurements were used to discriminate between vestibulodynia cases and controls with high sensitivity and specificity. This data supports the feasibility of contemporaneous assessment of vulvar mucosa and underlying musculature in the pelvic region, offering the hope of a more precise case definition for vestibulodynia and related disorders.
Massimo Della Valle nominato Linceo
Creators: Mauro Gargano
Publisher: name: Media Inaf
Year: 2022

Si sono concluse il 27 luglio scorso le elezioni dei soci dell’Accademia nazionale dei Lincei. Come socio corrispondente per la classe di Scienze fisiche, matematiche e naturali è stato eletto – insieme, fra gli altri, alle astrofisiche Monica Colpi della Bicocca e Marica Branchesi del Gssi – l’astronomo dell’Inaf di Napoli Massimo Della Valle
Physiological regulation of the heat shock response by glutamine: implications for chronic low-grade inflammatory diseases in age-related conditions
Creators: name: Fernandes Cruzat, Vinicius
Publisher: name: Torrens University Australia
Year: 2022
Subjects: Preventative health care

description: Aging is an intricate process modulated by different molecular and cellular events, such as genome instability, epigenetic and transcriptional changes, molecular damage, cell death and senescence, inflammation, and metabolic dysfunction. Particularly, protein quality control (chaperone systems) tends to be negatively affected by aging, thus leading to cellular senescence in metabolic tissues and, as a consequence, to the increasing dissemination of inflammation throughout the body. The heat shock (HS) response and its associated expression of the 70 kDa family of heat shock proteins (HSP70), which are anti-inflammatory molecular chaperones, are found to be markedly decreased during muscle inactivity and aging, while evidence supports the loss of HSP70 as a key mechanism which may drive muscle atrophy, contractile dysfunction, and reduced regenerative capacity. In addition, abnormal stress response is linked with higher incidence of neurodegenerative diseases as well as low-grade inflammatory diseases that are associated with physical inactivity and obesity. Therefore, strategies to increase or, at least, to maintain the levels of HSP70, and its accompanying HS response to stress, are key to reduce biological cell dysfunctions that occur in aging. In this sense, physical exercise is of note as it is the most powerful inducer of the HS response, comparable only to heat stress and fever-like conditions. On the other hand, the amino acid l-glutamine, whose production within the skeletal muscle and liberation into the blood stream is dependent on muscle activity, is a potentializer of HSP70 expression and HS response, particularly via its entering in hexosamine biosynthetic pathway (HBP). Herein, we discuss the collaborative role of glutamine (and its donors/precursors) and physical exercise (mostly responsible for glutamine release into the circulation) as potential tools to increase HSP70 expression and the HS response in the elderly.
Матеріали курсу «Європейські практики наукової досконалості в цифрову еру 2025». Проєкт «Зміцнення лідерства та спроможності ЄС у сфері науки та інновацій» (101175767—EU_STRENGHTS—ERASMUS-JMO-2024-HEI-TCH-RSCH)
Creators: name: Єгорченков, Олексій
Publisher: name: Zenodo
Year: 2025
Subjects: EU_STRENGHTS
RESEARCH EXCELLENCE
DATA ANALYSIS
R

description: Презентація містить навчальні матеріали за темами:

1)  Основи аналізу даних в R. Візуалізація даних в R

 

Матеріали курсу «Європейські практики наукової досконалості в цифрову еру 2025». Проєкт «Зміцнення лідерства та спроможності ЄС у сфері науки та інновацій» (101175767—EU_STRENGHTS—ERASMUS-JMO-2024-HEI-TCH-RSCH)*. 

*Проєкт фінансується Європейським Союзом. Висловлені думки та погляди є лише особистими думками авторів і не обов'язково відображають позицію Європейського Союзу чи Виконавчого агентства з освіти та культури ЄС (EACEA). Європейський Союз та EACEA не несуть відповідальності за ці погляди.