cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Dyscolus aquator Moret 2020, sp. nov.
Creators: name: Moret, Pierre
name: Murienne, Jérôme
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Carabidae
Dyscolus
Dyscolus aquator

description: Dyscolus aquator Moret sp. nov.
urn:lsid:zoobank.org:act: 0CB9ECC0-83A7-4D5D-BCC5-18118ABFAD0F
Figs 7–8
Etymology
Latin adjective meaning ‘related to water’.
Type material
Holotype
ECUADOR • ♂; Pichincha Province, Tandayapa, Bellavista Lodge, Waypoint 81; 0°0′56.6″ S, 78°40′49.1″ W; 2250 m a.s.l.; 2 Nov. 2015; P. Moret leg.; QCAZ.
Paratypes (3 ♂♂, 4 ♀♀)
ECUADOR – Pichincha Province • 1 ♂; same collection data as for holotype; CPM • 1 ♀; same collection data as for holotype; MNHN • 1 ♀; same collection data as for holotype; COI voucher PM081- 01, BOLD sequence SUM213-18; CPM • 2 ♂♂, 1 ♀; Pichincha Province, Tandayapa, Bellavista, Cascada; UTM 0758443, 9998631; 2100 m a.s.l.; 25 Feb. 2010; P. Moret leg.; under stone; CPM • 1 ♀; Tandayapa, Bellavista Lodge; 0.0147º S, 78.6833º W; 2200 m a.s.l.; 9 Nov. 2010; D. Maddison leg.; COI voucher PM510, BOLD sequence SUM310-18; OSAC.
Diagnostic description
Habitus: Fig. 7. Wingless. Body length: 10.2–11.9 mm. Body shiny black; basal ¾ of the femora and basal ½ of the tibiae dark brown; rest of the legs, antennae and mouthparts reddish brown. Elytral microsculpture transverse. Head average, eyes moderately bulging, mandibles long and acute. Pronotum elongate, cordiform, hind angles right angled, sharp; two pairs of lateral setae. Elytra narrow, humeri wholly effaced, striae deep, entire, with traces of punctation; third interval with three setae in most specimens (four setae on both elytra of one paratype and on the right elytron of another); subapical sinuation very deep; apex with a small acute tooth at sutural angle. Last visible abdominal ventrite with one pair (♂) or two pairs (♀) of setae along its apical margin. Legs slender; fourth metatarsomere without subapical dorsolateral setae, apical lobes parallel, the outer lobe 1.5 times longer than the inner lobe. Male genitalia: Fig. 8. Middle section of the median lobe straight in lateral view, feebly arcuate distally, apex triangular in lateral view, very short; endophallus without sclerotized structure, except for a subapical denticle. Female genitalia: unstudied.
Comparisons
See below under D. incommunis Moret sp. nov.
Habitat
Riparian in the montane forest on the Western slope of the Andes, at around 2200–2250 m a.s.l. The 2100 m elevation indicated on the labels of the specimens collected in 2010 is wrong, the correct elevation is 2200 m.
Geographic distribution
Southern end of the Chocó biogeographic region in northwestern Ecuador. Only known from the type locality, probably microendemic.
description: Published as part of Moret, Pierre & Murienne, Jérôme, 2020, Integrative taxonomy of the genus Dyscolus (Coleoptera, Carabidae, Platynini) in Ecuadorian Andes, pp. 1-55 in European Journal of Taxonomy 646 on pages 14-15, DOI: 10.5852/ejt.2020.646, http://zenodo.org/record/3829682
Structure-activity studies on bacterial efflux inhibitors
Creators: name: Blankson, Gifty Ayensu
Publisher: name: No Publisher Supplied
Year: 2016

description: Antibiotic resistance poses a significant challenge in anti-infective therapy.  There are several mechanisms involved in antibiotic resistance with efflux being a major determinant.  Overcoming efflux will allow for the reintroduction of old antibiotics and prevent the development of resistance to new antibiotics.  Several bacterial efflux pump inhibitors (EPIs) have been discovered, but none of these compounds have been FDA-approved for use in humans.  There is a need for a systematic study of some of these inhibitors to gain a better understanding of their structure activity relationship (SAR).  This work focuses on the SAR studies conducted on two classes of known EPI inhibitors.     Analogues of aryl piperazines (biphenyl piperazines and naphthalene amines) were synthesized and tested for their EPI activity.  None of the compounds in this series exhibited EPI activity and thus no further exploration was done on their SAR.  Structurally simpler analogues of phenylalanine-arginine β-naphthylamide (PAβN) were also designed and an SAR study conducted on the three different scaffolds proposed.  The three scaffolds include the “normal” amides, the “reverse” amides and the secondary amine series.  Although these scaffolds exhibited some similarities in their SAR, there were some differences.  In all cases, the 1,5-diphenylpentane core was the preferred substituent on the right hand side of the molecules.  For the left hand side, diaminopentane was the preferred substituent.  Further studies revealed that N5 substitution was detrimental to EPI activity.    The “reverse” amides had better activity when compared against their analogous “normal” amides.  The data indicated that a bis-alkylaryl was necessary for activity and that there was preference for the aryl to be hydrophobic.  A methylene insertion in the reverse amides series gave a compound that caused 512-fold reduction in the minimum inhibitory concentration (MIC) of clarithromycin (PAβN, the historical EPI standard offered a 4-fold reduction in MIC).  The amine analogues also offered some active compounds with one of these compounds causing a 128-fold reduction in the MIC of clarithromycin.  (These tests were done in E. coli).  Some success was achieved in P. aeruginosa; two compounds when independently co-administered with levofloxacin resulted in a 32-fold decrease in the MIC of levofloxacin.
Where are the promises of America?
Creators: name: Bonet, Sally Wesley
Publisher: name: No Publisher Supplied
Year: 2016

description: This study investigated the ways that newly resettled Iraqi, Muslim refugee families are enacting, defining, and critiquing citizenship in their new American contexts. Through a three year ethnographic, multi-lingual and multi-sited study, I examine the following question: “How are refugee families who live in poverty making themselves and being made into particular kinds of citizens through their everyday encounters with institutions of the welfare state?” Data collection sites included refugee homes, refugee resettlement agencies, local non-profits, welfare offices, courts, and hospitals. Participants included four focal, Iraqi, Muslim families, as well as several employees of a refugee resettlement agency and several of their Iraqi clients. Refugee youth, who oftentimes have porous and interrupted educational trajectories come to their urban public schools with many needs; many eventually age out of public education. Youth who attended urban public schools suffered discrimination, a lack of care, and silencing and overly punitive techniques by their teachers. Refugee families who live in poverty suffered as a result of a welfare system that prioritizes “self-sufficiency” above all else. Parents found themselves pushed into immediate employment by resettlement agents, with the threat of homelessness looming overhead. This oftentimes locked them into low-wage work, with no health-benefits, working long hours. Over 60% of Iraqi adults in the study reported trauma-related mental health problems, as well as chronic illnesses. All of them lacked access to healthcare after their initial federally funded healthcare benefits lapsed, leaving them without medical attention.   In sum, refugees’ experiences with the state and the very institutions tasked with their care left them unable to realize the bright futures they had hoped to find in the U.S. Through these punitive and exclusionary encounters with the state, refugees are learning key lessons about their place in society. Participants questioned the meaning of citizenship, and framed the project of American resettlement as a broken promise. Care for refugees requires robust state institutions that can provide for their unique needs. Staging interventions to improve the lives of refugees necessitates bucking current neoliberal trends which dispossess refugees, once again, of their abilities to aspire to and realize better futures.
Agroiconota urbanae Buzzi 1996
Creators: name: Sekerka, Lukáš
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Chrysomelidae
Agroiconota
Agroiconota urbanae

description: Agroiconota urbanae Buzzi, 1996 stat. restit.
Agroiconota urbanae Buzzi, 1996a: 1 (original description, incl. fig.).
Agroiconota subvittata [misidentification]: BOROWIEC (1996): 125 (faunistics); BOROWIEC (2005): 63 (Figs 15–16).
Type locality. Brazil, São Paulo, Jundiaí, Serra do Japi.
Type material. Holotype in the Departamento de Zoologia, Universidade Federal do Paraná, Brazil, not examined.
Remarks. BUZZI (1996a) described this species from a single specimen, provided a detailed description and figure of dorsal habitus, enabling identification of this taxon. BOROWIEC (1998b) synonymized it with A. subvittata based on similar colour pattern formed by red stripes on yellow elytra. However, the holotype of A. subvittata has the red stripes irregular due to punctures with large black areolae, particularly in the first and second stripe, while A. urbanae has these regular and bordered with small black punctures (see Figs 15 and 37 in BOROWIEC 2005). Therefore I restore the species status of A. urbanae. The specimen of A. subvittata from Corumbá published by BOROWIEC (1996) belongs to A. urbanae (L. Borowiec, pers. comm.).
Distribution. Brazil: Mato Grosso do Sul (BOROWIEC 1996), São Paulo (BUZZI 1996a).
description: Published as part of Sekerka, Lukáš, 2016, Taxonomic and nomenclatural changes in Cassidinae (Coleoptera: Chrysomelidae), pp. 275-344 in Acta Entomologica Musei Nationalis Pragae 56 (1) on page 283, DOI: 10.5281/zenodo.5305725
The number of lattice points in irrational polytopes
Creators: name: Borda, Bence
Publisher: name: No Publisher Supplied
Year: 2016

description: The discrepancy | t P ∩ Z^d | - lambda (P) t^d is studied as a function of the real variable t>1, where P is a polytope in R^d with at least one vertex not in Z^d. For a special class of cross polytopes and orthogonal simplices defined in terms of algebraic numbers the discrepancy is proved to be the sum of an explicit polynomial of t and a randomly fluctuating term of smaller order of magnitude. This phenomenon has not yet been described in the literature for any convex body. A general discrepancy bound is proved for polytopes the coordinates of the vertices of which all belong to a given real quadratic field. As a corollary a new property of the regular dodecahedron is obtained. Finally, answering a question of Beck, a formula is given for the variance of a random fluctuation arising in a lattice point counting problem on the plane. The main methods used are Fourier analysis and the theory of Diophantine approximation.
MOESM1 of A method for allocating low-coverage sequencing resources by targeting haplotypes rather than individuals
Creators: name: Ros-Freixedes, Roger
name: Gonen, Serap
name: Gorjanc, Gregor
name: Hickey, John
Publisher: name: Figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 1: Figure S1. Expected haplotype imputation accuracy against the accumulated haplotype sequencing coverage, as estimated using a novel population-based imputation method (Battagin and Hickey, unpublished). A description of the prototype algorithm that was developed for the imputation of consensus haplotypes under the LCSeq approach and the simulated results on which the AlphaSeqOpt method is based. We generated 1x sequence data for the sires from a simulated population. The x-axis represents the expected accumulated coverage that each haplotype would receive. The y-axis represents the percentage of alleles phased and imputed for each haplotype. The imputation accuracy increased with the accumulated haplotype coverage until it plateaued. Haplotypes with a sequencing coverage of 10x accumulated from 20 individuals sequenced at 1x were imputed to the whole population with an accuracy of 0.88. Haplotypes with a sequencing coverage of 15x or 20x accumulated from 30 or 40 individuals sequenced at 1x were imputed to the whole population with an accuracy of 0.93 or 0.97, respectively. For accurate inference of a consensus haplotype, a certain amount of sequencing coverage must be accumulated. According to the results above, 10x or 15x could be good target coverages for the haplotypes
Cassida catenata
Creators: name: Sekerka, Lukáš
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Chrysomelidae
Cassida
Cassida catenata

description: Cassida catenata (Boheman, 1855)
Coptocycla catenata Boheman, 1855: 262 (original description).
Coptocycla dorsalis Boheman, 1855: 322 (original description), syn. nov.
Type localities. Coptocycla catenata: ‘Java’ [fixed by lectotype designation]; C. dorsalis: ‘Java’.
Type material examined. Coptocycla catenata: LECTOTYPE (designated by BOROWIEC 1999a): pinned, ‘ Java. | Mellb [w, p, s] || Type.[w, p, s] || LECTOTYPE | des. L. Borowiec [r, p, cb] || NHRS-SRAH | 000000266 [w, p, cb]’ (NHRS).
Coptocycla dorsalis: HOLOTYPE: pinned, ‘Mus. | Westerm. [w, p, cb] || Java | Maj. 1814 | Dorsalis | Bohem. [w, hw, cb, brown frame]’ (ZMUC).
Remarks. Cassida catenata is one of the commonest species in SE Asia, distributed from continental Malaysia to Sumba (BOROWIEC & ŚWIĘTOJAŃSKA 2016). It has a very variable colour pattern, ranging from a uniformly yellow dorsum to a primarily black discs of pronotum and elytra. The typical form has the disc of elytra black with numerous yellow spots and the disc of pronotum black with two yellow spots.
BOHEMAN (1855) also described C. dorsalis from Java, from the collection of Westermann. This taxon remained unknown to subsequent workers and was listed only in catalogues (see BOROWIEC 1999a). The original type specimen was located in ZMUC, where Westermann’s collection is housed. In my opinion this taxon represents a black form of C. catenata as it differs from the latter only in colouration. Since both taxa were described in the same publication I followed the Principle of the first reviser (ICZN 1999: Article 24.2) and chose the name C. catenata as valid, since it has been mentioned in numerous publications and is mostly correctly applied. The black form of C. catenata was also described as C. ferrari (Spaeth 1904), already synonymized by BOROWIEC (2001).
Cassida catenata was also recorded from the southern foothills of the Eastern Himalaya (e.g. MAULIK 1919), however, that population is probably a distinct taxon and was thus not included in the distribution of the species.
Distribution. Indonesia (eastwards to Sumba) and Malaysia (peninsular and Sarawak) (BOROWIEC & ŚWIĘTOJAŃSKA 2016).
description: Published as part of Sekerka, Lukáš, 2016, Taxonomic and nomenclatural changes in Cassidinae (Coleoptera: Chrysomelidae), pp. 275-344 in Acta Entomologica Musei Nationalis Pragae 56 (1) on pages 283-284, DOI: 10.5281/zenodo.5305725
Additional file 1 of McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes
Creators: name: Hafez, Dina
name: Aslihan Karabacak
name: Krueger, Sabrina
name: Yih-Chii Hwang
name: Li-San Wang
name: Zinzen, Robert
name: Ohler, Uwe
Publisher: name: Figshare
Year: 2017
Subjects: subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplementary figures. (PDF 9185 kb)
Charidotella (Charidotella) fumosa
Creators: name: Sekerka, Lukáš
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Chrysomelidae
Charidotella
Charidotella fumosa

description: Charidotella (Charidotella) fumosa (Boheman, 1855)
Coptocycla fumosa Boheman, 1855: 156 (original description).
Metriona obnubilata Weise, 1921: 200 (original description), syn. nov.
Type localities. Coptocycla fumosa: ‘Cayenna’. Metriona obnubilata: Brazil, Amazonas, Rio Autáz.
Type material examined. Coptocycla fumosa: HOLOTYPE: pinned: ‘ Cayen [w, p, s] || Bhn. [w, p, s] || Type. [w, p, s] || NHRS-SRAH | 000000446 [w, p, cb]’ (NHRS).
Metriona obnubilata: HOLOTYPE: glued: ‘ Rio | Autaz [w, p, cb] || Amazon | Roman [w, p, cb] || nov. [w, p, s] || Metriona | obnubilata | m. [w, hw by Weise, s] || NHRS-SRAH | 000000474 [w, p, cb] ’ (NHRS).
Remarks. WEISE (1921) described Metriona obnubilata from a single specimen and compared it to M. glaucovittata (Erichson, 1847). BOROWIEC (1989) transferred it to Charidotella Weise, 1896 and the taxon was listed only in catalogues (see BOROWIEC 1999a). The holotype has a pattern on the underside of elytra forming lateral stripe on each elytron and a band across elytra in their basal third. It also has subangulate humeral angles, a diffuse brownish pattern on pronotal disc and the specimen is conspecific with the holotype of C. fumosa. Metriona obnubilata is thus synonymized with the latter species.
BOHEMAN (1855) did not state exactly how many specimens he had at his disposal. However, based on the original description and the single length measurement, I assume he had only one.
Distribution. Argentina: Tucumán (SPAETH 1942); Brazil: Amazonas (WEISE 1921), Mato Grosso (SPAETH 1942); Ecuador (BOROWIEC 1996); French Guyana (BOHEMAN 1855); Guyana (BOROWIEC 1996); Peru (e.g. SPAETH 1942, BOROWIEC 1996).
description: Published as part of Sekerka, Lukáš, 2016, Taxonomic and nomenclatural changes in Cassidinae (Coleoptera: Chrysomelidae), pp. 275-344 in Acta Entomologica Musei Nationalis Pragae 56 (1) on page 285, DOI: 10.5281/zenodo.5305725
Charidotella (Charidotella) rubrotestacea
Creators: name: Sekerka, Lukáš
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Chrysomelidae
Charidotella
Charidotella rubrotestacea

description: Charidotella (Charidotella) rubrotestacea (Boheman, 1855) stat. restit.
Coptocycla rubrotestacea Boheman, 1855: 423 (original description).
Type locality. ‘Columbia’.
Type material examined. HOLOTYPE: pinned: ‘Colum- | bia [w, p, cb] || Pazur | dakhi [w, hw, s] || Type. [w, p, s] || NHRS-JLKB | 000021793 [w, p, cb]’ (NHRS).
Remarks. BOHEMAN (1855) described Coptocycla rubrotestacea presumably from a single specimen. Subsequently, the species was listed only in catalogues (see BOROWEC 1999a) and BOROWIEC (1989) synonymized it with Charidotella ventricosa (Boheman, 1855). However, C. rubrotestacea differs by the uniformly pale explanate margin of elytra (humeral spots always present in C. ventricosa), subcircular body shape (subtriangular in C. ventricosa), clypeus with an apical sulcus (smooth in C. ventricosa), and less convex elytra with much lower and obtuse postscutellar tubercle (high and sharp in C. ventricosa). I therefore restore the species status of C. rubrotestacea. The quite unusual combination of morphological features of this species is similar only to Charidotella morio (Fabricius, 1801), which differs by the primarily black ventral side (uniformly yellow in C. rubrotestacea), explanate margin of elytra declivous in their entire length (canaliculate in apical third in C. rubrotestacea), more constricted pronotum in its basal half, thus appearing subpentagonal (broadly rounded and nearly semicircular in C. rubrotestacea), and large basal teeth of claws (small in C. rubrotestacea). Charidotella rubrotestacea is so far known only from the holotype.
Distribution. Colombia (BOHEMAN 1855).
description: Published as part of Sekerka, Lukáš, 2016, Taxonomic and nomenclatural changes in Cassidinae (Coleoptera: Chrysomelidae), pp. 275-344 in Acta Entomologica Musei Nationalis Pragae 56 (1) on pages 285-286, DOI: 10.5281/zenodo.5305725
Extensions of the Hilbert-multi-norm in Hilbert $C^*$-modules
Creators: name: Abedi, Sajjad
name: Moslehian, Mohammad Sal
Publisher: name: arXiv
Year: 2024
Subjects: subject: Functional Analysis (math.FA)
subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 46L05, 46B15, 47L10

description: Dales and Polyakov introduced a multi-norm $\left( \left\|\cdot\right\|_n^{(2,2)}:n\in\mathbb{N}\right)$ based on a Banach space $\mathscr{X}$ and showed that it is equal with the Hilbert-multi-norm $\left( \left\|\cdot\right\|_n^{\mathscr{H}}:n\in\mathbb{N}\right)$ based on an infinite-dimensional Hilbert space $\mathscr{H}$. We enrich the theory and present three extensions of the Hilbert-multi-norm for a Hilbert $C^*$-module $\mathscr{X}$. We denote these multi-norms by $\left( \left\|\cdot\right\|_n^{\mathscr{X}}:n\in\mathbb{N}\right)$, $\left( \left\|\cdot\right\|_n^{*}:n\in\mathbb{N}\right)$, and $\left( \left\|\cdot\right\|_n^{\mathcal{P}\left(\mathfrak{A} \right) }:n\in\mathbb{N}\right)$. We show that $\left\|x\right\|_n^{\mathcal{P}\left(\mathfrak{A} \right) }\geq\left\|x\right\|_n^{\mathscr{X}}\leq \left\|x\right\|_n^{*}$ for each $x\in\mathscr{X}^n$. In the case when $\mathscr{X}$ is a Hilbert $\mathbb{K}\left(\mathscr{H}\right)$-module, for each $x\in\mathscr{X}^n$, we observe that $\left\|\cdot\right\|_n^{\mathcal{P}\left(\mathfrak{A} \right)}=\left\|\cdot\right\|_n^{\mathscr{X}}$. Furthermore, if $\mathscr{H}$ is separable and $\mathscr{X}$ is infinite-dimensional, we prove that $\left\|x\right\|_n^{\mathscr{X}}=\left\|x\right\|_n^{*}$. Among other things, we show that small and orthogonal decompositions with respect to these multi-norms are equivalent. Several examples are given to support the new findings.
description: 16 pages, Accepted by Positivity
Charidotis annularis
Creators: name: Sekerka, Lukáš
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Chrysomelidae
Charidotis
Charidotis annularis

description: Charidotis annularis (Boheman, 1855)
Coptocycla annularis Boheman, 1855: 207 (original description).
Coptocycla Signoreti Boheman, 1855: 210 (original description), syn. nov.
Type localities. Coptocycla annularis: ‘Brasilia’; C. signoreti: ‘Brasilia ad Rio Janeiro’.
Type material examined. Coptocycla annularis: SYNTYPE: pinned, ‘ Rio Jan [w, p, s] || F. Sahlb. [w, p, cb] || Type. [w, p, s] || NHRS-SRAH | 000000524 [w, p, cb]’ (NHRS).
Coptocycla signoreti: SYNTYPE: pinned, ‘ Rio Jan [w, p, s] || F. Sahlb. [w, p, cb] || Type. [w, p, s] || NHRS-JLKB | 000021832 [w, p, cb]’ (NHRS).
Remarks. Both taxa were described in the same book by BOHEMAN (1855) just a few pages apart. SPAETH (1914) transferred both to Charidotis Boheman, 1854. SPAETH (1936) revised the genus and separated the two taxa only by colour: C. annularis with red disc of elytra and C. signoreti with black.
Examination of both types as well as additional historic specimens from various institutions revealed that the colour of elytra is variable in these taxa. Even the syntype of C. signoreti has variegated elytra, basally and centrally more black and laterally reddish-brown. Uniformly black specimens are very rare in collections and as result C. signoreti was listed only in catalogues while C. annularis was repeatedly reported (see BOROWIEC 1999a, BOROWIEC & ŚWIĘTOJAŃSKA 2016). In my opinion both nominal taxa represent colour morphs of a single species as all other morphological characters are identical. Such variability in colouration is not uncommon in similar species of Charidotis and it is known for instance in C. auroguttata Boheman, 1855 and C. porosula Spaeth, 1902.
Since both taxa were described in the same publication I followed the Principle of the first reviser (ICZN 1999: Article 24.2) and chose the name C. annularis as valid for this taxon, as it has been used recently and the species is more frequently identified in the collections under this name.
Distribution. Brazil: Bahia (SPAETH 1936), Minas Gerais (BOROWIEC 2009c), Paraná (FERNANDES & LINZMEIER 2012), Rio de Janeiro (BOHEMAN 1855, FLINTE et al. 2009), São Paulo (SPAETH 1936).
description: Published as part of Sekerka, Lukáš, 2016, Taxonomic and nomenclatural changes in Cassidinae (Coleoptera: Chrysomelidae), pp. 275-344 in Acta Entomologica Musei Nationalis Pragae 56 (1) on page 289, DOI: 10.5281/zenodo.5305725
Anti-inflammatory, epigenetic regulatory role of phytochemicals and pkpd modeling of pharmacological effects
Creators: name: Boyanapalli, Sarandeep S S
Publisher: name: No Publisher Supplied
Year: 2016

description: Chronic inflammation is considered to play an important factor in neoplastic  progression via the induction of reactive oxygen, reactive nitrogen species and  induction of growth promoting cytokines. Thus, it is very important to develop new  drugs that can inhibit inflammation and prevent cancer formation or progression.  Dietary phytochemicals are derived from natural sources and are found commonly in  the fruits and vegetables consumed regularly as part of the diet. Understanding the  mechanism by which the natural compounds inhibit inflammation and prevent cancers  is very important and could pave way to developing new targets and drugs for  chemoprevention. During my dissertation, I have studied the anti-inflammatory  properties of phytochemicals like Curcumin, Phenethylisothiocyanate (PEITC) and  Ursolic acid (UA). The importance of Nrf2, a transcription factor in attenuating  inflammation was studied using macrophages from Nrf2 (+/+) and Nrf2 (-/-) mice.  The results showed that Nrf2 plays a major role in the anti-inflammatory effects of  Curcumin and PEITC as seen from the differences between Nrf2 (+/+) and Nrf2 (-/-)  mice macrophages. The anti-inflammatory effect of Curcumin was further evaluated  iii  in rats. The results showed that Curcumin suppressed lipopolysaccharide (LPS)  induced inflammation as well as some epigenetic modifying genes like DNA  methyltransferases and Histone deacetylases. The pharmacological response was  modeled using an indirect response approach.The epigenetic modulatory role of  PEITC was tested in LNCaP (androgne sensitive human prostate adenocarcinoma)  cells, the results revealed that PEITC inhibits DNA methylation and increased  transcription of RASSF1A, a tumor suppressor gene and in turn promotes apoptosis.  Ursolic acid (UA), a pentacyclic triterpenoid was studied for its anti-inflammatory  and epigeneitc modulatory role in PTEN-CaP2 cells (Prostate specific PTEN null  epithelial cell line). UA suppressed LPS induced inflammatory cytokines as well as  inhibited HDAC protein expression along with increasing the expression of Nrf2 a  master regulator of anti-oxidate stress response pathway and NQO1. Collectively, the  results demonstrated the anti-inflammatory and epigenetic modulatory potential of  phytochemicals in vitro and in vivo.
Dyscolus rivinus Moret 2020, sp. nov.
Creators: name: Moret, Pierre
name: Murienne, Jérôme
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Carabidae
Dyscolus
Dyscolus rivinus

description: Dyscolus rivinus Moret sp. nov.
urn:lsid:zoobank.org:act: 95AF0791-2EC1-42FD-862D-02F7BCFB1419
Figs 11–12
Etymology
Latin adjective meaning ‘riparian’.
Type material
Holotype
ECUADOR • ♂; Cotopaxi Province, Otonga; 2000 m a.s.l.; 7 Jul. 1998; I. Tapia leg.; QCAZ.
Paratypes (3 ♂♂)
ECUADOR – Cotopaxi Province • 1 ♂; same collection data as for holotype; QCAZ • 2 ♂♂; Otonga; 1950 m a.s.l.; 3–5 Jul. 2001; P. Moret leg.; berge de ruisseau; CPM.
Diagnostic escription
Wingless. Body length: 10.0– 11.7 mm. Very similar externally to D. incommunis Moret sp. nov., from which it differs in the following features. Base of the pronotum narrower, lateral margins less expanded near base, hind angles more obtuse and more rounded. Apex of elytra ended with a small but protruding and acute tooth, preceded externally by a short sinuation (Fig. 11). Fourth metatarsomere without subapical setae. Male genitalia (Fig. 12) with apex of the median lobe shorter, less acute, not sinuate in lateral view, endophallus unarmed, without a dense squamose area near apex, at most with a single feebly sclerotized squama. Female genitalia unknown.
Comparisons
Closely related to D. incommunis Moret sp. nov., from which it can be distinguished by a few but constant characters, especially the rounded hind angles of the pronotum, the apical tooth of the elytra and the unarmed endophallus.
Habitat
Riparian in the montane forest on the Western slope of the Andes, at around 1900–2000 m a.s.l. This hygrophile specialisation differs from the more mesic habitat of D. incommunis Moret sp. nov.
Geographic distribution
Southern end of the Chocó biogeographic region in northwestern Ecuador, 75 km south of the type locality of D. incommunis Moret sp. nov. Probably microendemic.
description: Published as part of Moret, Pierre & Murienne, Jérôme, 2020, Integrative taxonomy of the genus Dyscolus (Coleoptera, Carabidae, Platynini) in Ecuadorian Andes, pp. 1-55 in European Journal of Taxonomy 646 on pages 16-18, DOI: 10.5852/ejt.2020.646, http://zenodo.org/record/3829682
Additional file 1: Table S1. of Next-generation mapping: a novel approach for detection of pathogenic structural variants with a potential utility in clinical diagnosis
Creators: name: Barseghyan, Hayk
name: Tang, Wilson
name: Wang, Richard
name: Almalvez, Miguel
name: Segura, Eva
name: Bramble, Matthew
name: Lipson, Allen
name: Douine, Emilie
name: Lee, Hane
name: EmmanuĂ¨Le DĂŠlot
name: Nelson, Stanley
name: Vilain, Eric
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Primers used for qPCR validations of structural variants. List of primer sequences and corresponding annealing temperatures. Upper case letters indicate that the primer sequence is within the exon. (PDF 40 kb)
The anarchist inquisition
Creators: name: Bray, Mark
Publisher: name: No Publisher Supplied
Year: 2016

description: “The Anarchist Inquisition” examines how a nascent international human rights discourse grew out of a broader “ethics of modernity” in response to anarchist terrorism and state repression in Spain from 1893-1909. As authorities enhanced the scope of their arrests and torture and curtailed civil liberties in response to the bombing of a procession in Barcelona in 1896, an international movement for the rights of the victims of the Spanish state was born. In the next decade, several more instances of governmental brutality sparked campaigns that mobilized notions of human rights, even if they did not use the exact term. Using police records, press coverage, and correspondence between diplomats, activists and politicians in archives across Spain, France, the Netherlands, and England, I place Spain at the center of the story of how terrorism catalyzed the development of human rights.
Additional file 1: of Linagliptin versus sitagliptin in patients with type 2 diabetes mellitus: a network meta-analysis of randomized clinical trials
Creators: name: Khosro Keshavarz
name: Lotfi, Farhad
name: Sanati, Ehsan
name: Salesi, Mahmood
name: Hashemi-Meshkini, Amir
name: Jafari, Mojtaba
name: Mojahedian, Mohammad
name: Najafi, Behzad
name: Shekoufeh Nikfar
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Science Policy

description: Appendix. Search strategies. (DOC 215Â kb)
Entrance and persistence in alternative agriculture
Creators: name: Bruce, Analena
Publisher: name: No Publisher Supplied
Year: 2016

description: Social movements have inspired a new generation of Americans to take up farming.  The agri-food movement has created alternative food networks to promote organic or ecological farming practices and support the viability of family farms.  However, a study of beginning organic farmers suggests that they rely on non-farm wealth and outside income to stay in business. Experienced farmers face significant barriers to adopting organic practices and a high turnover rate.    I investigate how new agrarians enter alternative agriculture, and what kinds of factors explain their persistence in the face of daunting macro-economic trends.  I draw on early rural sociological theory about agricultural ladders, combining this conceptual tool with recent work on the agri-food movement.  I consider the role of participation in grassroots agri-food organizations, subsidies from non-farm income, inherited land, and the higher prices that come from direct marketing.  I use a case study of small-scale, organic farmers in southern Ohio, many of whom participate in a regional organization for organic farmers.  My study finds that the common characterization of farmers as either first-generation farmers with no prior background in agriculture or experienced farmers who “go organic” needs revising.  This study highlights what I call returning farmers: people with a family connection to farming who pursued nonfarm careers but found new opportunities and inspiration to re-enter agriculture later in life.  I develop a typology of three pathways into alternative agriculture: nontraditional first-generation "greenhorn" farmers who are inspired by the food movement to enter agriculture, “returning farmers” who have a family history of farming but pursued non-farm careers before returning to agriculture, and “legacy” farmers with family land who have decided to practice alternative agriculture.    Greenhorns and returning farmers use nonfarm capital to establish small-scale, diverse specialty crop and livestock farms.  Because of the obstacles they face, many develop nontraditional revenue strategies to support their farms, and continue relying on non-farm income or wealth.  In contrast, the Organic Valley Coop and market demand for certified organic grain and dairy products have created opportunities for legacy farmers to transition into organics and work as full-time farmers, thus meeting the movement’s ideals.
Additional file 1: of scDual-Seq: mapping the gene regulatory program of Salmonella infection by host and pathogen single-cell RNA-sequencing
Creators: name: Avital, Gal
name: Roi Avraham
name: Fan, Amy
name: Hashimshony, Tamar
name: Hung, Deborah
name: Yanai, Itai
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: scDual-Seq protocol. This file includes the detailed scDual-Seq protocol. (PDF 265 kb)
Design, fabrication, and characterization of bioactive amphiphilic polymers as cardiovascular therapeutics
Creators: name: Chan, Jennifer Wing-Yee
Publisher: name: No Publisher Supplied
Year: 2016

description: Recent advancements in cardiovascular drug-eluting stents (DES) have significantly improved clinical outcomes and survival rates in patients with arteries blocked by fat and cholesterol accumulation. Current DES utilize a cytotoxic or immunosuppressive agent to overcome earlier issues of restenosis, or smooth muscle cell (SMC) hyperproliferation, but the drugs and polymer overcoat are associated with an increased risk of late-stent thrombosis, or blood clot formation due to delayed re-endothelialization and hypersensitivity reactions. Both of these issues restrict blood flow and may cause angina, myocardial infarction, and/or death. An alternative therapeutic strategy is to target upstream events in the restenosis and thrombosis cascades, such as high levels of oxidative stress.        In this research, bioactive micelles and nanoparticles were developed to minimize cellular interactions of oxidized low-density lipoprotein (oxLDL), which has been shown to induce excessive cellular proliferation and platelet activation. These formulations are comprised of amphiphilic macromolecules (AMs) containing a sugar-based hydrophobic domain and a hydrophilic poly(ethylene glycol) tail. The results indicate that when SMCs are exposed to high levels of oxidized lipid stimuli, AM nanoassemblies inhibited oxLDL uptake, downregulated scavenger receptor expression, and attenuated scavenger receptor gene transcription, and thus significantly suppressed SMC proliferation with minimal cytotoxicity. The potential for bioactive AM delivery was further evaluated as stent coatings, where AMs were self-assembled into monolayer coatings on metal oxide substrates using grafting-from and grafting-to approaches. In the grafting-from technique, molecules were polymerized from the surface in a multi-step synthesis, whereas polymers were pre-synthesized before end-functionalization to the surface in the grafting-to method. Densely packed layers of bioactive AMs gradually released from substrates, significantly suppressing SMC proliferation and platelet adsorption. Variations in the grafting method, functional end group, and linker length yielded a range of AM grafting densities, release rates, and reductions in SMC proliferation and platelet adsorption, suggesting that the bioactive AM release profile can be tuned to match physiological events in the restenosis and thrombosis cascades. Overall, the findings in this thesis highlight the potential of using AM formulations as stand-alone bioactive agents or for controlled therapeutic delivery from coronary stents to minimize restenosis and thrombosis.
Charidotis circulifera Boheman 1862
Creators: name: Sekerka, Lukáš
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Chrysomelidae
Charidotis
Charidotis circulifera

description: Charidotis circulifera Boheman, 1862
Charidotis circulifera Boheman, 1862: 370 (original description).
Charidotis exornata Weise, 1921: 203 (original description), syn. nov.
Type localities. Charidotis circulifera: ‘ Brasilia (Ega)’ [= Tefé in the State of Amazonas]; C. exornata: ‘[Brazil, Amazonas] Rio Autáz: Cururuzinho’.
Type material examined. Charidotis circulifera: SYNTYPES: 1 spec., pinned, ‘ Brasil. | Ega [hw] [w, p, s] || Baly. [w, p, s] || Type. [w, p, s] || NHRS-SRAH | 000000546 [w, p, cb]’ (NHRS); 1 spec., pinned, ‘ Type [w, p, s, c, rf] || Ega [hw] | Baly Coll. | 1905—54. [w, p, cb] || Charidotis | circulifera | Boh | Ega [w, hw by Baly, cb] || Coll | Bates | Stevens | Named by | Boheman | Type [hw by Baly on underside of the preceding label]’ (BMNH); 1 spec., pinned, ‘ Ega [hw] | Baly Coll. | 1905—54. [w, p, cb]’ (BMNH).
Charidotis exornata: HOLOTYPE: pinned, ‘ Rio | Autaz [w, p, cb] || Amazon | Roman [w, p, cb] || sept. [w, p, s] || Autaz, Sa. Amelia 12/9 14. | Pa blad i skogem [= on leaf in forest] A. Rm[oman] [w, hw by Roman, cb] || Type. [w, p, s] || exornata | m. [w, hw by Weise, cb] || exornata W. | cognata ab. [w, hw by Spaeth, cb] || NHRS-JLKB | 000021800 [w, p, cb] ’ (NHRS).
Remarks. Charidotis exornata was described explicitly from a single specimen (WEISE 1921). SPAETH (1931b, 1936) considered it as an aberrant specimen of C. cognata Boheman, 1855. Based on the labels Spaeth cited, it is unclear why he considered it as a peculiar form of the latter species, as it is very different in size and morphological features. Charidotis exornata is distinct by the very broadly elliptical pronotum presented only in certain species, i.e. theses 261–266 in SPAETH (1936), while C. cognata has a narrower pronotum and coarser punctation of elytra. In my opinion C. exornata is conspecific with C. circulifera Boheman, 1862 as both taxa are morphologically similar, differing only in colouration. The latter has a dorsum with two concentric rings, black and red, and a yellow central spot, while in C. exornata the red inner ring is expanded and forms a large central spot without a yellow marking. For these reasons I synonymize C. exornata with C. circulifera.
Distribution. Brazil: Amazonas (BOHEMAN 1862, WEISE 1921).
description: Published as part of Sekerka, Lukáš, 2016, Taxonomic and nomenclatural changes in Cassidinae (Coleoptera: Chrysomelidae), pp. 275-344 in Acta Entomologica Musei Nationalis Pragae 56 (1) on pages 290-291, DOI: 10.5281/zenodo.5305725
Additional file 1: Figure S1. of Comparison of online marketing techniques on food and beverage companiesâ   websites in six countries
Creators: name: Bragg, Marie
name: Eby, Margaret
name: Arshonsky, Josh
name: Bragg, Alex
name: Gbenga Ogedegbe
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Virology
subject: Computational Biology

description: Overview of Qualitative Content Analysis Coding Process. Flow chart explaining the coding process. (PDF 123Â kb)
Charidotis circumscripta Boheman 1855
Creators: name: Sekerka, Lukáš
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Chrysomelidae
Charidotis
Charidotis circumscripta

description: Charidotis circumscripta Boheman, 1855
Charidotis circumscripta Boheman, 1855: 24 (original description).
Charidotis rubrocincta Boheman, 1855: 23 (original description), syn. nov.
Type localities. Charidotis circumscripta: ‘Brasilia’; C. rubrocincta: ‘Brasilia’.
Type material examined. Charidotis circumscripta: LECTOTYPE (designated by BOROWIEC 1999a):pinned, ‘ Brasil.[w, p, s] || Schneid. [w, p, s] || Type. [w, p, s] || LECTOTYPE | des. L. Borowiec [r, p, cb] || NHRS-SRAH | 000000552 [w, p, cb]’ (NHRS).
Charidotis rubrocincta: HOLOTYPE: pinned, ‘ Brasil [w, p, s] || Bhn. [w, p, s] || Type. [w, p, s] || NHRS-JLKB | 000021829 [w, p, cb]’ (NHRS).
Remarks. BOHEMAN (1855) described C. rubrocincta based on a dark coloured specimen with explanate margins and a reddish-brown ventral surface. The colouration was the only character used to separate this taxon from C. circumscripta, as other characters are identical in both descriptions. Types of both taxa have the same size, punctation and convexity of elytra, proportion of antennae and differ only in colouration of pale parts, which are yellow in C. circumscripta and reddish-brown in the other specimens of C. rubrocincta. The latter taxon is known only from the holotype while C. circumscripta is a relatively common species in eastern Brazil and I attribute the colouration of C. rubrocincta to a preservation artefact. Since both taxa were described in the same publication I followed the Principle of the first reviser (ICZN 1999: Article 24.2) and chose C. circumscripta as the valid name for this species, as it was correctly applied and used in literature until recently.
Distribution. Brazil: Mato Grosso, Paraná (BOROWIEC 1996), Rio de Janeiro (BOHEMAN 1855; BOROWIEC 1996, 2002, 2009c).
description: Published as part of Sekerka, Lukáš, 2016, Taxonomic and nomenclatural changes in Cassidinae (Coleoptera: Chrysomelidae), pp. 275-344 in Acta Entomologica Musei Nationalis Pragae 56 (1) on page 291, DOI: 10.5281/zenodo.5305725
MOESM1 of Statistical methods to derive efficacy estimates of anti-malarials for uncomplicated Plasmodium falciparum malaria: pitfalls and challenges
Creators: name: Prabin Dahal
name: Simpson, Julie
name: Dorsey, Grant
name: GuĂŠrin, Philippe
name: Ric Price
name: Stepniewska, Kasia
Publisher: name: Figshare
Year: 2017
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Additional tutorial, formulae and results.
Interfacial and transport phenomena of bioinspired vesicles
Creators: name: Chu, Xiaolei
Publisher: name: No Publisher Supplied
Year: 2016

description: In the design of drug delivery vehicles, self-assembled nanostructured materials such as liposomes, polymerosomes and hybrid biomaterials bears increasing attentions. The key challenges in the optimal modification of these soft materials is the prediction of resultant morphologies in favor of circulation time, as well as the optimization of surface properties to adjust the interactions between bio-inspired materials with nanoparticles and bio-macromolecules such as peptides, proteins and nucleic acids.  One of the ways to overcome these challenges is through the development of flexible modeling tools to address physical phenomena under a mesoscopic scale, allowing us to deeply investigate interfacial problems of nanostructured materials in a dynamic approach. In this work, we utilize the Dissipative Particle Dynamics simulation technique to examine the interaction between peptide mimetic nanoparticles (nanopin) and multicomponent vesicles. We study the role of nanopin architecture and cholesterol concentration on the capture of the nanopins by the bilayer, their insertion and post-insertion self-organization. Furthermore, we investigate the transportation of hybrid vesicle with various concentrations of end-functionalized lipids. We draw correlation among the morphology, composition and mechanical properties of the vesicle and flow conditions. Our results can potentially help in the design of drug delivery system with respect to their transport in blood capillaries, and tissue engineering for the design of microfluidic devices with better in-vivo transportation efficiency. Our study can also provide guidelines for designing peptide-mimetic nanoparticles or macromolecules which can interface with living cells to serve as sensors for applications in medicine, sustainability and energy.
Additional file 4: Table S2. of Characterizing endophytic competence and plant growth promotion of bacterial endophytes inhabiting the seed endosphere of Rice
Creators: name: Walitang, Denver
name: Kiyoon Kim
name: Munusamy Madhaiyan
name: Kim, Young
name: Yeongyeong Kang
name: Tongmin Sa
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 60506 Virology

description: Functional traits and metabolic activity associated to endophytic adaptation of bacterial endophytes in seeds of rice. (DOCX 25 kb)