cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Single-nucleotide polymorphism rs10036727 in the SLIT3 gene is associated with osteoporosis at the femoral neck in older Mexican postmenopausal women
Creators: name: Hidalgo-Bravo, Alberto
name: Hernández-Medrano, Cristina
name: Sevilla-Montoya, Rosalba
name: Rivera-Paredez, Berenice
name: Ramirez-Salazar, Eric Gustavo
name: Flores-Morales, Jeny
name: Patiño, Nelly
name: Salmeron, Jorge
name: Valdés-Flores, Margarita
name: Velázquez-Cruz, Rafael
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy
subject: Hematology

description: Osteoporosis (OP) remains a major public health problem worldwide. The most serious complications of this disease are fragility fractures, which increase morbidity and mortality. Management of OP represents an economic burden for health systems. Therefore, it is necessary to develop new screening strategies to identify the population at risk and implement preventive measures. We previously identified the SNPs rs3801387 in WNT16, rs7108738 in SOX6, rs10036727 in SLIT3 and rs7584262 in PKDCC as associated with bone mineral density in postmenopausal women through a genome-wide association study. The aim of this study was to validate those SNPs in two independent cohorts of non-related postmenopausal women. We included 1160 women classifying them as normal, osteopenic or osteoporotic and a group with hip fragility fracture. Genotyping was performed using predesigned TaqMan assays. The variants rs10036727 and rs7108738 showed a significant association with BMD at the femoral neck. SLIT3 has been previously proposed as a potential biomarker and therapeutic resource. Our results provide new evidence regarding a possible involvement of SLIT3 in bone metabolisms and encourage the development of more studies in different populations to support these observations.
Sonnenfleckenzeichnung Nr. 23134.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.07.1969, erstellt von Antoine Zelenka
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Past shifts in the general circulation: causation, structure, and effects on hydroclimate
Creators: name: Rutz, Jonathan James
Publisher: name: University of Utah
Year: 2012
Subjects: Atmospheric
Change
Circulation
Climate
General
Hydroclimate

description: There is now abundant evidence that an important consequence of recent climate change is the displacement of key elements within the global circulation. Considerable uncertainty exists with regard to the sign and magnitude of these changes, and it is also not fully understood how the roles of individual anthropogenic forcings contribute toward their cause. Because of the potential impacts they may impose upon hydroclimate, these changes in the circulation, and particularly their causation, are of high interest. Our primary goal is to differentiate between the various anthropogenic forcings driving these shifts.  We analyze the results from long time-slice simulations performed using a state-of-the-art atmospheric general circulation model, which show that important features in the general circulation have shifted poleward since the preindustrial era. Many of these shifts are characterized by pronounced seasonality and exhibit a tendency to be maximized during the summer months of each respective hemisphere. Furthermore, the magnitude of these shifts tends to exhibit a greater variability both over the southern hemisphere and within the extratropical regions. While reductions in ozone and increases of greenhouse gas concentrations have played a role in causation, the indirect effects from feedback mechanisms have been dominant. In most cases, a linear addition of the changes produced in those experiments prescribed with individual forcings is nearly identical to that for an experiment performed with all forcings included. This result is remarkably consistent, indicating that effects of the mechanisms that lead to changes in the circulation are approximately linearly additive.
Improved data transmission via inductive link for neural recording devices
Creators: name: Smith, William Anthony
Publisher: name: University of Utah
Year: 2012
Subjects: Implant
Inductive
Link
Neural
Wireless

description: Fully integrated, implantable, and wireless neural interface systems typically re-quire a forward data link in addition to the telemetry link that transmits data from  the chip. One popular way to create this forward data link is to amplitude modulate the magnetic fi eld of the inductive link that provides the device with wireless power. However, the limitations of these channels when loaded with a recti fier and amplitude modulated have not previously been characterized, and this lack of understanding caused previous versions of the Integrated Neural Interface (INI) to have forward data communication issues, which needed to be corrected for the next generation of the device, INIR8. This thesis  first develops an analytical method of characterizing this sort of wireless channel. It then shows measurement data that verifies the validity of the model in the desired region of operation. The available bandwidth as determined by this analytical method, and confirmed by simulation, is insufficient for many applications. Therefore, the next subject of this thesis is to increase the data rate beyond what the bandwidth of the system can intrinsically support by using an equalization technique. This technique is shown to support very robust data recovery under a variety of operating conditions and to data rates much higher than otherwise possible. Another way to improve the reliability of data recovery is to develop a robust digital control system with error detection capabilities. This was done for INIR8, and works very reliably. The end result of this eff ort is a very robust forward data communication in INIR8, as well as a new analytical method for characterizing inductively coupled channels with certain loads and modulation techniques.
Sonnenfleckenzeichnung Nr. 23202.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.10.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 23241.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.11.1969, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 23224.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.11.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 23086.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.06.1969, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 23130.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.07.1969, erstellt von Antoine Zelenka
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 23187.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.09.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 23244.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.11.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Prehydration mitigates damage accrued from prolonged periods of desiccation in cultured shoot apices of Syntrichia ruralis
Creators: name: Slate, Mandy L.
name: Brinda, John C.
name: Coe, Kirsten K.
name: Greenwood, Joshua L.
name: Stark, Lloyd R.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Plant Biology

description: We hypothesised that a prehydration period (exposure to humid air) should mitigate the damaging effects of short or long periods of desiccation in a desert moss, Syntrichia ruralis. Cultured uniclonal shoots of S. ruralis were dried rapidly, equilibrated at 42% relative humidity (RH), allowed to remain at this RH for 1–50 days, and either (1) prehydrated (24 h at 100% RH) then rehydrated with liquid water, or (2) rehydrated directly using liquid water without a prehydration treatment, and assessed using chlorophyll fluorescence and visual damage. At both 20 min and 24 h postrehydration, all chlorophyll fluorescence measures (Fm, Fv/Fm, ΦPSII, qP) were higher in shoots that were prehydrated. Prehydrated S. ruralis shoots also had less visual leaf damage 7 d postrehydration. Duration-dry (DD) had an overall negative effect for all fluorescence measures on shoots immediately after rehydration, an effect that dissipated at 24 h postrehydration in three of the four fluorescence measures (Fm, Fv/Fm, ΦPSII). Leaf damage was not influenced by Duration-dry. Although no interaction was detected between Prehydration and Duration-dry treatments, the benefits of prehydration were accentuated based on fluorescence metrics Fv/Fm and ΦPSII, when shoots are exposed to longer drying periods. A prehydration treatment implemented just prior to hydration with liquid water significantly mitigated shoot damage accrued from a prior rapid drying event and DDs of up to 50 d at 42% RH. Based on photosynthetic efficiency, prehydration conferred greater effects at longer DDs. Experiencing humid conditions prior to rainwater mitigates damage incurred during prolonged desiccation.
title: Care home closure and the influence of domiciliary care supply: Evidence from England (accepted)
Creators: name: Allan, Stephen
Publisher: name: Sage
Year: 2022

description: There is a general trend of increased marketisation of long-term care (LTC) services across Europe, with the natural consequence that market forces will affect the supply of LTC. At the same time, there has been a rapid increase in the use of home-based provision for those requiring LTC support. However, there is little evidence as what the effects of growing domiciliary care provision has on the markets for institutional forms of care. This is important from a policy point of view in terms of managing local markets, access to services, the quality of services and inequality. Using data from England for all care homes and domiciliary care providers registered to provide care to older people during 2014-16 we assessed if increased domiciliary care supply was linked to increased likelihood of care home closure. Using Cox proportional hazard models of care home closure controlling for care home characteristics including quality and local area measures of needs and income, the findings provide no evidence that domiciliary care provision is a substitute for care homes. In some specifications there was even a complementary relationship between the two forms of social care: increased domiciliary care supply significantly reduced the likelihood of care home closure. Potential reasons for the complementary relationship found, including market integration, older population growth, reduced informal care provision and market signals, and the implications for European LTC policy, are discussed.
description: Author's Accepted Manuscript
Sonnenfleckenzeichnung Nr. 23176.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.09.1969, erstellt von Antoine Zelenka
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 23190.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.09.1969, erstellt von Antoine Zelenka
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 23146.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.08.1969, erstellt von Johann Dürst
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Consumer expectations and consumer satisfaction with prenatal care at three public health clinics
Creators: name: Ripley, Ida
Publisher: name: University of Utah
Year: 2012
Subjects: Prenatal care
Public hospitals - Outpatient services

description: This study was designed to consider factors that might be used to predict which women will drop out of prenatal care in public health clinics, and consumer satisfaction with prenatal care in public health clinics. Data were collected from 124 women initiating care at three clinics in Salt Lake City and Ogden.  Variables were organized into derived measures of socioeconomic status, social support, knowledge and expectations at the onset of care.  These variables were then used to predict which women would stay in prenatal care and examined the data in relationship to satisfaction with care received.  Conclusions are that expectations play an important role in satisfaction ratings and that it is possible to identify women at the onset of prenatal care who are more likely to drop out of care.  These findings have implications for further research in consumer satisfaction, as well as policy implications for public health planners and care providers.
Sonnenfleckenzeichnung Nr. 23233.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.11.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Inference of Breakpoints in High-dimensional Time Series
Creators: name: Chen, Likai
name: Wang, Weining
name: Wu, Wei Biao
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: For multiple change-points detection of high-dimensional time series, we provide asymptotic theory concerning the consistency and the asymptotic distribution of the breakpoint statistics and estimated break sizes. The theory backs up a simple two-step procedure for detecting and estimating multiple change-points. The proposed two-step procedure involves the maximum of a MOSUM (moving sum) type statistics in the first step and a CUSUM (cumulative sum) refinement step on an aggregated time series in the second step. Thus, for a fixed time-point, we can capture both the biggest break across different coordinates and aggregating simultaneous breaks over multiple coordinates. Extending the existing high-dimensional Gaussian approximation theorem to dependent data with jumps, the theory allows us to characterize the size and power of our multiple change-point test asymptotically. Moreover, we can make inferences on the breakpoints estimates when the break sizes are small. Our theoretical setup incorporates both weak temporal and strong or weak cross-sectional dependence and is suitable for heavy-tailed innovations. A robust long-run covariance matrix estimation is proposed, which can be of independent interest. An application on detecting structural changes of the U.S. unemployment rate is considered to illustrate the usefulness of our method.
Sonnenfleckenzeichnung Nr. 23216.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.10.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
An evaluation of a passive nitrous oxide monitor.
Creators: name: Davis, Mark Bitner
Publisher: name: University of Utah
Year: 2012
Subjects: Adminstration and Dosage
Anesthesia

description: Exposure limits to waste nitrous oxide (N2O) in dental operatories have been established by the National Institute for Occupational Safety and Health (NIOSH) at 25 ppm (average per period of administration) and by the American Conference of Governmental Industrial Hygienist (ACGIH average should prevent increased risk of spontaneous abortion and significant decrements in psychomotor and cognitive functions or other adverse health effects.  Dentists and assistants can measure their personal exposure with clip-on devices called passive monitors.  Using passive diffusion, the monitor collects N2O through its sampling face when exposed.  After exposure, the monitors are analyzed by thermal desorption, and an average exposure value in ppm is calculated based on the length of time the badge was exposed.  One such passive monitor, the Vapor-Trak N2O badge, was evaluated for its ability to accurately measure N2O exposures commonly found in dental office settings.  Eighteen side-by-side area sampling runs were conducted in two dental offices which used N2O at least 15 hours/week and in a laboratory enclosure.  Thirty-five Vapor-Trak badges and a Miran 1B2 portable infrared spectrophotometer (PIS) were used to measure N2O exposures ranging from 0 to 13000 ppm.  Exposures of 100 ppm in waiting areas/hallways and 100 â€" 1300 ppm in operatories were not uncommon.  Carbon dioxide (CO2), temperature, and humidity levels were also measured.  For each sampling run, the PIS result was considered the true N2O exposure and regression analysis between badge and PIS results indicated the accuracy of the badge over various TWA intervals between 0 to 1372 ppm. In the laboratory and in the dental office, the Vapor-Trak badge exceeded the (+25%) OSHA accuracy requirements for measuring nitrous oxide exposure, at the NIOSH Recommended Exposure Limit (REL) of 25 ppm and the ACGIH Threshold Limit Value (TLV) of 50 ppm and for all badge results up to 108 ppm.  Above 108 ppm, badge results were not as accurate, but accurate enough to indicate overexposure.  The Vapoar-Trak nitrous oxide monitor was found to sample consistently at any concentration between 0 and 1372 ppm (5.9% coefficient of variation between badges measuring the same concentration).  Thus, Vapor-Trak nitrous oxide monitor is a simple and effective clip-on device for measuring breathing air concentrations of nitrous oxide in dental offices.  Any result over 50 ppm should trigger controls to reduce the nitrous oxide exposure below the
Neonatal glucose determinations obtained from an umbilical artery catheter: evaluation for accuracy using an in vitro model
Creators: name: Butler, Leslie Ann
Publisher: name: University of Utah
Year: 2012
Subjects: Blood sugar monitoring
Arterial catheterization

description: Accuracy of glucose values is crucial in the management of the critically ill neonate. Sampling for these values may be obtained from an umbilical artery catheter to avoid the trauma of a heelstick. The risk of dextrose contamination must be appreciated when utilizing the umbilical artery catheter as the sampling site. An in vitro study was conducted to evaluate glucose measurements from an umbilical artery catheter. Randomization of blood withdrawal increments and irrigation of a nondextrose-containing solution through the catheter was performed to minimize the risk of dextrose contamination. Repeated measures analysis of variance (ANOVA) revealed a significant difference between measured and baseline glucose for all withdrawal amounts and varying flush volumes. This inability to approximate the baseline glucose necessitates a need for further studies if the umbilical artery catheter is to be relied upon for glucose sampling.
Exploration of provider information processing in the care of patients with diabetes in primary care
Creators: name: Wallace, Melissa Ann
Publisher: name: University of Utah
Year: 2012
Subjects: Clinical practice guidelines
Diabetes management
Electronic health records
Information processing
Primary care

description: The purpose of this study was to explore the schemata primary care providers use to process information during an encounter with a patient with diabetes, the sources of information, and the completeness of those sources. This study was descriptive and qualitative using techniques from focused ethnography. A purposive sample of primary care providers in an urban area of Utah participated. The sample included 1 nurse practitioner, 2 family practice residents, and 7 primary care physicians. The data were collected using one-to-one, unstructured interviews, passive participation observation, and semistructured interviews. All interviews were audio recorded and transcribed. Observations took place in each clinic as the providers cared for patients with diabetes. Field notes were written for each observation. The semistructured interviews were based upon analysis of the field notes. Each transcript was coded line by line using descriptive codes to identify the characteristics of patients with diabetes and the sources and content of information gathered by providers. Coding then continued to build the smaller codes into clusters and networks.
Modeling branched wiring networks using inversion
Creators: name: Brewer, Carl Petter
Publisher: name: University of Utah
Year: 2012
Subjects: Aging aircraft
Inversion
Network topology
Reflectometry
SSTDR
Steepest descent
Aircraft wiring

description: A network algorithm is developed to analyze a branched wire network to determine the branch and fault topology of the network, using an array of hand-held (EM) electro-magnetic field sensors in conjunction with a SSTDR (Spread-Spectrum Time Domain Reflectometry) wire tester. The algorithm provides an analysis of the  convolved reflectometry data collected at multiple data points along a test wire by the field sensors. The faults are located using a reconstruction of forward and backward traveling waveforms created from a mathematical inversion of a collection of convolved  reflectometry data. The methods and algorithms developed to model the topology of the test wires are described. The topology refers to the locations of the major reflection points within a branched network, and the lengths and connections of the segments of  wire that exist between reflectors. Simulations are developed to determine the effectiveness of the algorithm without the limitations of the test hardware. Tests are performed in a controlled lab environment to assess the abilities of the developed algorithms.
Study of the social and psychological needs of the pharmacists of Utah
Creators: name: Morris, Douglas Eugene
Publisher: name: University of Utah
Year: 2012
Subjects: Pharmacists - Utah
Job satisfaction

description: Pharmacy has contributed greatly to mankind since its inception as a profession.  In recent years many changes have taken place in the practice of pharmacy and in the role of the pharmacist in his professional work.  Since dissatisfaction had been noted by some writers, it was felt important to investigate the nature of the secondary human needs of pharmacists which could have an effect on their work satisfaction.  The specific purposes of the study were: (1) to determine the extent to which the need hierarchy, as described by Maslow, was fulfilled by members of the profession of pharmacy in Utah; and (2) to determine if there was a correlation between the degree of satisfaction derived from work in pharmacy and the branch of pharmacy in which the respondents were working.  A questionnaire was sent to 500 registered pharmacists in the State of Utah.  The respondents were asked to rate the degree of fulfillment they received from work in pharmacy in the social and psychological human needs.  The results were analyzed statistically and the conclusions were: (1) the pharmacists as a whole perceived a deficiency in every item of the need-fulfillment hierarchy; (2) no correlation existed between the degree of satisfaction derived from work in pharmacy and the branch of pharmacy in which the respondents were working; and (3) pharmacists who were owners of pharmacies received more fulfillment of the higher order needs than did pharmacists who were employees.
TESS Experiments: Impact of Response Scale Direction on Survey Responses to Factual/Behavioral Questions
Creators: name: Keusch, Florian
Publisher: name: Roper Center for Public Opinion Research
Year: 2022

description: Time-sharing Experiments for the Social Sciences (TESS) offers researchers the opportunity to capture the internal validity of experiments. Investigators submit proposals, and TESS fields successful proposals for free on a representative sample of adults in the United States. This experiment was conducted to examine how scale ordering impacts survey respondent answers to factual questions and how other scale features may moderate such impacts. Respondents were randomly assigned to one of 12 treatment groups and surveyed on frequency of mental and physical health behaviors/experiences. Response scale order (high to low or low to high), orientation (vertical or horizontal), and the precision of the scale labels (vague quantifiers, numerical/precise quantifiers, or a combination of vague quantifier with numerical definition) varied by treatment group. A total of 1,729 respondents participated. After answering the set of treatment questions, respondents completed 15 filler questions followed by a set of validation questions which revisited the domains of mental health and health behaviors asked in the treatment questions but set up as open-ended numerical responses. This allowed for analysis of correlations between treatment and validation responses and interactions between scale ordering, orientation, and precision of labels.
Impact of functional information upon healthcare outcomes: a randomized controlled clinical trial.
Creators: name: Wick, Jeffrey Paul
Publisher: name: University of Utah
Year: 2012
Subjects: Patient Satisfaction
Medical Informatics

description: The goal most eye care providers is the preservation or improvement of visual function.  Several test, such as the National Eye Institute's Visual Function Questionnaire (VFQ), have been developed to objectively quantify visual function.  Although the usefulness of such functional tests are well documented for research and outcomes analysis, their utility in the daily practice of medicine is not clear.  A study was conducted to assess the impact of the provision of functional information to provide on selected parameters.  The results of the study suggest that the availability of the functional information expands the number of topics discussed by the provider and the patient, and the VFQ has a favorable influence on patient satisfaction.  Although the CFQ dies appear to have some effect upon provider decision-making, the provider does not necessarily perceive this effect.  The CFQ remains a valuable tool for research and outcome analysis, and the VFQ may have a favorable impact upon the daily practice of medicine.  More research needs to be conducted to determine whether or not selected ophthalmic patients populations may benefit from functional test administered at the point of care.
Transcription of poliovirus RNA in vitro
Creators: name: Hey, Timothy Denver
Publisher: name: University of Utah
Year: 2012

description: Studies in cells of all types indicate that DNA serves as the template for both its own replication as well as the synthesis of RNA.  This observation, therefore, requires that the RNA-containing viruses must either coordinate or provide unique enzymology for the replication of their RNA genomes.  One strategy which has developed to circumvent this dilemma has been the direct use of RNA as template  for RNA  synthesis.  RNA-dependent RNA synthesis, while central to the genome replication of many important RNA viruses, remains largely biochemically uncharacterized.  In an effort to elucidate the components and mechanism of RNA dependent RNA synthesis, an in vitro transcription system for polio RNA was developed and studied.  The system consisted of   the poliovirus RNA polymerase (3DPo1) and a "Host Factor (HF) fraction from uninfected cells.  The transcription of polio RNA was strictly dependent on 3DPo1, HF, and a poliovirion RNA template.  The transcription products contain both plus- (identical to the template) and minus- (complement of the template) strand RNA.  The size of the product RNA was heterogeneous, the largest being apparently twice template length.  The large product RNA results from 3DPol utilizing the 3' end of the template as a primer, therefore, generating product RNA covalently linked to the template.  In an effort to study the mechanism involved in the production of template linked product RNA, the 3DPo1 and HF reactions were separated.  Preincubation of template RNA with HF, followed by its removal by phenol extraction, results in a template modification which allows 3DPol to transcribe the RNA in the absence of added HF.  Analysis of reinsulated as well as active HF mediated elongating template RNAi indicate the priming 3' ends are heterogeneous and are a result of random nucleolytic events.  No evidence was found to imply that the natural 3' poly (A) end of the template was involved in self-priming.  It is  proposed  that template cleavages adjacent  to or in base paired regions of secondary structure, fortuitously provide template linked primers Pol for 3DPol,  which when elongated appear to be up to dimer length..""
Sonnenfleckenzeichnung Nr. 23230.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.11.1969, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Optical coherence tomography angiography in primary eye care
Creators: name: Coffey, Alexandra M
name: Hutton, Emily K
name: Combe, Louise
name: Bhindi, Pooja
name: Gertig, Demi
name: Constable, Paul A
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: Science Policy

description: Optical coherence tomography angiography (OCT‐A) is a non‐invasive imaging modality for assessing the vasculature within ocular structures including the retina, macula, choroid and optic nerve. OCT‐A has a wide range of clinical applications in various optometric conditions which have been independently reported in the literature. This paper aims to present a review of the current literature on the clinical application of OCT‐A in optometric practice as well as to analyse and evaluate the quality of the available evidence. This review included 78 articles from a literature search conducted on 26 May 2019 across the following databases: Cochrane Library of Systematic Reviews, Medline, Scopus and Web of Science. Primary ocular pathologies discussed in this review include glaucoma, diabetic retinopathy, age‐related macular degeneration, myopia, acquired and congenital macular dystrophies, epiretinal membrane, retinal vein occlusion, retinitis pigmentosa, choroidal melanoma, uveitis, central serous chorioretinopathy, amblyopia and optic neuropathies. Primary outcome variables included vessel density, foveal avascular zone area and diameter, flow velocity and flow index. This review aims to evaluate the evidence available for OCT‐A applications in diagnosis and prognosis of ocular conditions in an optometric setting.
High sensitivity measurement of androgens by two-dimensional-high pressure liquid chromatography-tandem mass spectrometry
Creators: name: Blamires, Takara L
Publisher: name: University of Utah
Year: 2012
Subjects: Androgens
HPLC-MS/MS
Mass spectrometry

description: Dehydroepiandrosterone and androstenedione are precursors of sex hormones; testosterone is a bioactive precursor of steroids responsible for development of secondary male characteristics. Abnormal androgen production may cause changes in gender-specific physiology and measurements are useful in diagnosing androgen and estrogen related disorders. We developed a high sensitivity two-dimensional liquid chromatography tandem mass spectrometry (LC-MS/MS) method for measurement of dehydroepiandrosterone,  androstenedione, and testosterone. Stable isotope-labeled internal standards were added to 200 ?L of serum and extracted into methyl-tert-butyl ether. The solvent was evaporated and steroids derivatized with hydroxylamine. Instrumental analysis was performed on an API 4000 (Applied Biosystems) LC-MS/MS utilizing a TurboIonsprayTM source in positive multiple reaction monitoring (MRM) mode. Quantitation was performed with AnalystTM software. The quantitative MRM transitions monitored were (m/z): 304 to 253 Da for DHEA; 306 to 255 Da for d2-DHEA; 317 to 124 Da for androstenedione; 324 to 128 Da for d7-androstenedione; 304 to 124 Da for testosterone; and 307 to 112 Da for d3-testosterone. Two-dimensional chromatographic separation was performed using a Phenomenex Gemini C6 cartridge as the first dimension and a Phenomenex Gemini C18 column as the second dimension. Injection-to-injection interval was 4.5 minutes. The assay was linear up to 9.2 ng/mL for DHEA, 42.5 ng/mL for androstenedione, and 25.8 ng/mL for testosterone.
Disaster nursing preparation.
Creators: name: Riddle, Lana Myrtle Belcher
Publisher: name: University of Utah
Year: 2012
Subjects: Emergencies
Hospitals

description: On April 8, 1970, at 5:00 P.M., a mock disaster occurred in Salt Lake City.  This disaster drill was panned and carried out at considerable time, effort and expense to be sure the people of Salt Lake City and County would receive the best health service possible in the event of a disaster, either natural or military.  The purpose of this study was to determine if the nursing profession participated in the planning phase of the community disaster plan or was actively engaged in the disaster drill of April 8, 1970.  The purpose was also to determine if nurses are lacking in disaster nursing experience or disaster education and to determine if knowledge of first aid principles and disaster management were increased as a result of participation of the drill.  To accomplish the purpose, a copy of the disaster drill plans and protocol was obtained.  Also a questionnaire was developed from material presented in the pilot project report on disaster nurse preparation of the National League for Nursing.  The questionnaire was designed to elicit information that could be subjected to statistical treatment, specifically:  1. The program from which subject graduated.  2. The paramedical courses subject attended.  3. If the participant had had disaster nursing experience.  4. The participant's activity in the disaster drill.  6. If the participant had received instruction related to seven functions that would confront nurses in disaster nursing.  7. The participant's knowledge of first aide and disaster management.  The total sampled population consisted of 33 licensed practical nurses, 13 associated registered nurses, 24 diploma registered nurses, 6 baccalaureate registered nurses.  These nurses were employed by two Salt Lake City hospitals.  Findings of this study indicate that:  1. Nurses were not included in the preparation of the community disaster plan. 2. The disaster drill did not provide nurses with an opportunity to practice disaster nursing skills or to increase their knowledge of first aid or disaster management preparation.  3. In general nurses are lacking in knowledge of first aid and disaster management preparation. As a result of this study, the following recommendations are made:  1. That nursing services of hospitals provide instruction in disaster nursing for their nurses.  2. That disaster nursing instruction is included in all education programs in nursing. 3. That courses, conferences, or workshops related to disaster nursing are offered by the local or national nursing organization.  4. That the local nursing association delegate a committee to notify and work with the disaster preparation planning committee.