cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplementary Material -Serum sclerostin levels in response to vitamin D3, omega-3 fatty acids and exercise: a 3-year prospective analysis of the DO-HEALTH trial
Creators: name: Tsourdi, Elena
name: Gaengler, Stephanie
name: Rauner, Martina
name: Dawson-Hughes, Bess
name: Orav, E. John
name: Tsai, Li-Tang
name: Lang, Wei
name: Kanis, John A.
name: Theiler, Robert
name: Egli, Andreas
name: Bischoff-Ferrari, Heike A.
name: C. Hofbauer, Lorenz
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 321001
subject: Clinical nutrition
classificationCode: 320208
subject: Endocrinology

description: Context: Sclerostin inhibits canonical Wnt signalling, a pathway promoting bone formation. The effects of vitamin D3, omega-3 fatty acids (omega-3s), and exercise on sclerostin serum levels are unclear.Objective: To investigate the effects of 2000 IU/d vitamin D3, 1g/d omega-3s, and a simple home-based strength exercise program (SHEP), alone or in combination, on serum levels of sclerostin.Design, setting and participants: Sclerostin levels were a pre-defined secondary outcome of DO-HEALTH, a double blind, randomized controlled trial in generally healthy and physically active older adults in five European countries.Outcome Measures: Changes in yearly serum sclerostin levels over 3 years, adjusted for age, sex, prior falls, study site, baseline BMI, and baseline sclerostin level.
sj-docx-2-cpa-10.1177_07067437211043395 - Supplemental material for Health System-Level Evaluation of Tele-Mental Health Services Among Children and Adolescents in Ontario, Canada
Creators: name: Toulany, Alene
name: Kurdyak, Paul
name: Gandhi, Sima
name: Fu, Longdi
name: Grewal, Seena
name: Kulkarni, Chetana
name: Saunders, Natasha
name: Vigod, Simone
name: Guttmann, Astrid
name: Chiu, Maria
name: Pignatiello, Antonio
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-2-cpa-10.1177_07067437211043395 for Health System-Level Evaluation of Tele-Mental Health Services Among Children and Adolescents in Ontario, Canada by Alene Toulany, Paul Kurdyak, Sima Gandhi, Longdi Fu, Seena Grewal, Chetana Kulkarni, Natasha Saunders, Simone Vigod, Astrid Guttmann, Maria Chiu and Antonio Pignatiello in The Canadian Journal of Psychiatry
QUANTUM INFORMATION METHODS FOR ENTANGLEMENT COMPUTATION: THE CASE OF THE HELIUM ATOM.
Creators: name: SICCARDI, STEFANO
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: The thesis aims to study the applicability of techniques of Quantum Information theory to complex systems, like molecules and biomolecules.
Recently, concepts of Quantum Information theory have been applied to the study of phenomena involving molecules, for instance the interaction light-biomolecules. In particular, the entanglement has been proposed to quantify the non-classicality of interactions.
The computation of molecular structures and interactions, on the other hand, has been studied for decades mainly to understand reactions? kinetic and energetic characteristics. It is not straightforward to apply these methods to the computation of quantum correlations.
We have therefore explored the computability of such effects using Quantum Information techniques. We started with the study of the electronic correlations in the Helium atom, that is the simplest non trivial case, in order to evaluate the computational problems and to develop approximate methods suitable to more complex systems. We start recalling the definition and basic properties of entanglement, as it is considered
in Quantum Information theory. We illustrate how it can be measured and the difficulties one encounters when identical particles are involved, then we concentrate on the case of Helium in particular. In order to study the entanglement in Helium, we treat separately the singlet and the triplet configurations. The method we use consists in computing the reduced density
matrix and then the entropy. The possible choices of coordinates, basis functions and computation strategies are discussed, together with their impact on the algorithms. The reduced, single-electron von Neumann and linear entropy for several low-energy eigenstates of Helium are computed by means of a simple configuration-interaction variational
method.
Additional file 2 of The burden of hospital admissions for skeletal dysplasias in Sri Lanka: a population-based study
Creators: name: Kolambage, Yasas D.
name: Walpita, Yasaswi N.
name: Liyanage, Udari A.
name: Dayaratne, Buddika M.K.D.R.
name: Dissanayake, Vajira H.W.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Supplementary Table S2 ICD-10 codes used for skeletal dysplasias.
sj-docx-1-rse-10.1177_07419325211046760 – Supplemental material for Supports to Improve Academic Outcomes With Racially and Ethnically Minoritized Youth: A Review of Research
Creators: name: Fallon, Lindsay M.
name: DeFouw, Emily R.
name: Berkman, Talia S.
name: Cathcart, Sadie C.
name: O’Keeffe, Breda V.
name: Sugai, George
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Education
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental material, sj-docx-1-rse-10.1177_07419325211046760 for Supports to Improve Academic Outcomes With Racially and Ethnically Minoritized Youth: A Review of Research by Lindsay M. Fallon, Emily R. DeFouw, Talia S. Berkman, Sadie C. Cathcart, Breda V. O’Keeffe and George Sugai in Remedial and Special Education
PREVENZIONE DELLA RESISTENZA A FARMACI CHEMIOTERAPICI: IL GLIOBLASTOMA COME PARADIGMA
Creators: name: BANELLI, BARBARA
Publisher: name: Universit� degli studi di Genova
Year: 2019

description: Chemoresistance in Glioblastoma (GBM) is one of the major pitfalls which concurs to the treatment failure in glioblastoma patients. KDMs family is an enzymatic class of ?epigenetic erasers? which are involved in chemoresistance and their expression is higher in glioblastoma cells resistant to Temozolomide (TMZ), the chemotherapic drug utilized in standard clinical protocols.
We have determined the biological and functional effects of JIB 04 and CPI-455, two KDM inhibitors, on glioblastoma cells in an in vitro and in vivo experimental plan. According to our results, both molecules are particularly effective against TMZ-resistant fraction of glioblastoma cells respect to the native ones.
JIB 04, in particular, has as its main target KDM5A, a KDMs member, and activates autophagic and apoptotic pathways, interferes with cell cycle progression, inhibits clonogenicity and dephosphorylation of Akt in PI3K pathway.
The in vitro treatments combining Temozolomide and JIB 04 showed that these molecules have a synergistic effect. Finally, we studied, in vivo, the permeability of JIB 04 through the blood-brain barrier and found that this molecule reaches the brain with bioactive concentrations. Besides, an in vivo pilot experiment in an orthotopic GBM xenograft model indicated a trend towards greater survival in mice treated with JIB04 (HR = 0.5).
We hypothesized that the combination of cytotoxic drugs like TMZ and molecules that act on the epigenome could offer the opportunity to develop new therapies for this invariably lethal disease.
Novel Inverse-Scattering Methods in Banach Spaces
Creators: name: TAVANTI, EMANUELE
Publisher: name: Universit� degli studi di Genova
Year: 2019

description: The scientific community is presently strongly interested in the research of new microwave imaging methods, in order to develop reliable, safe, portable, and cost-effective tools for the non-invasive/non-destructive diagnostic in many fields (such as medicine, civil and industrial engineering, ?). In this framework, microwave imaging techniques addressing the full three-dimensional nature of the inspected bodies are still very challenging, since they need to cope with significant computational complexity. Moreover, non-linearity and ill-posedness issues, which usually affects the related inverse scattering problems, need to be faced, too. Another promising topic is the development of phaseless methods, in which only the amplitude of the electric field is assumed to be measurable. This leads to a significant complexity reduction and lower cost for the experimental apparatuses, but the missing information on the phase of the electric field samples exacerbates the ill-posedness problems.
In the present Thesis, a novel inexact-Newton inversion algorithm is proposed, in which the iteratively linearized problems are solved in a regularized sense by using a truncated Landweber or a conjugate gradient method developed in the framework of the l^p Banach spaces. This is an improvement that allows to generalize the classic framework of the l^2 Hilbert spaces in which the inexact-Newton approaches are usually defined. The applicability of the proposed imaging method in both the 3D full-vector and 2D phaseless scenarios at microwave frequencies is assessed in this Thesis, and an extensive validation of the proposed imaging method against both synthetic and experimental data is presented, highlighting the advantages over the inexact-Newton scheme developed in the classic framework of the l^2 Hilbert spaces.
Muscular modifications in chronic spinal cord injured patients
Creators: name: INVERNIZZI, MARCO
Publisher: name: Universit� degli Studi del Piemonte Orientale Amedeo Avogadro
Year: 2014

description: In this thesis muscular modifications in chronic spinal cord injured patients have been
investigated. Using a translational approach, a mini-invasive muscular biopsy
technique in Spinal Cord Injured patients has been validated. Moreover, the possible
role of circulating levels of myostatin as a possible candidate biomarker for muscular
modifications in chronic SCI patients has been evaluated. Lastly, the molecular
modifications of PGE2 pathway on muscular specimens of chronic SCI patients has
been studied.
All material is original and based on direct Author ?s experience.
Additional file 4 of The efficacy and safety of apatinib plus capecitabine in platinum-refractory metastatic and/or recurrent nasopharyngeal carcinoma: a prospective, phase II trial
Creators: name: Tang, Lin-Quan
name: Li, Xiao-Yun
name: Li, Zhi-Ming
name: Liu, Zhi-Gang
name: Lin, Miao-Zhen
name: Zhou, Huan
name: Yu, Qi-Wen
name: Zhou, Jian
name: Zhao, Chong
name: Chen, Ze-Bin
name: Wang, Xi-Cheng
name: Peng, Jia-Yu
name: Chen, Qiu-Yan
name: Fang, Wen-Feng
name: Yang, Yun-Peng
name: Zhang, Bei
name: Xia, Liang-Ping
name: Hu, Pi-Li
name: Hu, Wei-Han
name: Li, Yi-Jie
name: Mai, Hai-Qiang
name: Cai, Xiu-Yu
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 4: Figure S6. Fig.S6- Post hoc analysis of potential factors influencing the efficacy of apatinib plus capecitabine.
Thermodynamic, kinetic and NMR relaxometric studies of Mn(II) complexes as MRI probes
Creators: name: FORGACS, Attila
Publisher: name: Universit� degli Studi del Piemonte Orientale Amedeo Avogadro
Year: 2017

description: The main goal of this thesis is the characterization in aqueous solutions of new Mn(II) complexes as MRI probes. Our investigation included thermodynamic, kinetic and detailed 1H and 17O NMR relaxometric measurements. We have taken into account Mn-complexes belonging to two different main types of structural units.
One encompasses the Mn(II) complexes containing the pentadentate coordinating units 6,6-((methylazanediyl)bis(methylene))dipicolinic acid. We considered several derivatives of the monomeric DPAMA ligand, including mono-, bi- and trinuclear bis-hydrated complexes (Chapter 4). In addition, we investigated a number of derivatives featuring different side arms and a couple of lipophilic derivatives (Chapter 5). All these complexes represent a fairly homogeneous series that has allowed us to obtain useful information on the relationship between the molecular structure, the thermodynamic stability and the relaxation parameters.
The other class of complexes are those containing the macrocyclic unit cyclen and two coordinating pendant arms. These macrocyclic derivatives have been studied in detail, considering the chemical nature of the pendant arms, their relative position (cis/trans), the possible presence of isomers with different states of hydration, the kinetic and thermodynamic stability of the complexes and their relaxometric properties (Chapter 6). The synthesis of two novel derivatives bearing hydrophobic pendant groups enabled the investigation of the binding association with human serum albumin (Chapter 7).
The global set of experimental results has allowed us to deepen our understanding of the chemistry of Mn(II) complexes as potential MRI probes. We are confident that the new information gained will help in the future design and development of more effective and safer MRI contrast enhancing agents.
Additional file 1 of Square-stepping exercise in older inpatients in early geriatric rehabilitation. A randomized controlled pilot study
Creators: name: Fränzel, Katja
name: Koschate, Jessica
name: Freiberger, Ellen
name: Shigematsu, Ryosuke
name: Zieschang, Tania
name: Tietgen, Svenja
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Biotechnology
Biological Sciences not elsewhere classified
Science Policy

description: Supplementary Materials 1.
title: Wirtschaftspolitische Interessen junger Menschen in Deutschland
Creators: name: Bürger, Tobias
name: Neto Romeira, Theresa
name: Zillinger, Sandra
name: Andrade, Ivo
Publisher: name: Bertelsmann Stiftung
publisherIdentifier: https://ror.org/01wj9hk44
publisherIdentifierScheme: ROR
Year: 2024
Subjects: Wirtschaftspolitik
Junger Mensch
Einstellung
Meinung

description: Mehr als die Hälfte der jungen Menschen in Deutschland zeigt Interesse an Wirtschaftsthemen. Zugleich beklagt jede:r Zweite, nicht über ausreichendes Wissen zu verfügen, um wirtschaftliche Nachrichten verstehen zu können. Die Wirtschaftspolitik der Parteien spielt für junge Menschen eine wichtige Rolle bei ihrer Wahlentscheidung. Doch nur wenige fühlen sich bei wirtschaftspolitischen Entscheidungen ausreichend berücksichtigt.
Understanding the disturbance of human recreation on wildlife using multiple dynamic agents within an IBM framework
Creators: name: Garcia, Soraida
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Behavioural ecology

description: As the need for outdoor recreation grows, the profound impact of recreational activities upon wildlife is a major concern. For example, the presence of humans may increase risk-averse behavior by wildlife, restricting access to essential resources, and reducing foraging, thereby negatively impacting breeding. Ultimately, the impacts that recreationists have on wildlife include directly or indirectly altering population structure and community composition. Unfortunately, understanding the impacts of recreating humans upon wildlife is a complex challenge that is dependent upon wildlife species and human activity types. Our understanding of human-wildlife relationships can be improved by combining results from empirical studies with simulation models to extrapolate mechanisms to a broader range of circumstances and investigate their implications. Accordingly, we developed an ABM modeling framework, that enables both dynamic virtual human and wildlife agents to change their actions. These changes are based upon their state as a consequence of their interactions with their environment and other virtual agents. A unique aspect of the framework we developed is the explicit simulation of both wildlife and human agent behavior as emergent rather than imposed. We use this framework to model the disturbance of birds, in the Lawrence Creek Forest Unit (LCFU) of Fort Harrison State Park, IN, by human recreation. We parameterize the model with human recreation data collected through an intercept survey of recreationists at the park and bird data from published studies. We compare our modeling framework to a more traditional model type where human behavior is imposed while wildlife behavior is emergent. Our results indicate that the frequency of humans entering the park influences the rates of disturbance of birds more than model types. Examining simulation behavior within our new framework, the utility and off-trail options had the most influence across all scenarios. These comparisons illustrate that the use of a modeling framework that allows managers to explore factors altering wildlife disturbance rates. Despite the marginal influence of model type upon our results, our research elucidates the value of a model that allows emergent behavior for multiple agent types. The emergent human and wildlife responses of simulated interacting agents provides new insight when managing these relationships. 
EDGE COMPUTING APPROACH TO INDOOR TEMPERATURE PREDICTION USING MACHINE LEARNING
Creators: name: Kim, Hyemin
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Coding, information theory and compression
Applied computing not elsewhere classified
Computational complexity and computability
Knowledge and information management
Information systems not elsewhere classified

description: This paper aims to present a novel approach to real-time indoor temperature forecasting to meet energy consumption constraints in buildings, utilizing computing resources available at the edge of a network, close to data sources. This work was inspired by the irreversible effects of global warming accelerated by greenhouse gas emissions from burning fossil fuels. As much as human activities have heavy impacts on global energy use, it is of utmost importance to reduce the amount of energy consumed in every possible scenario where humans are involved. According to the US Environmental Protection Agency (EPA), one of the biggest greenhouse gas sources is commercial and residential buildings, which took up 13 percent of 2019 greenhouse gas emissions in the United States. In this context, it is assumed that information of the building environment such as indoor temperature and indoor humidity, and predictions based on the information can contribute to more accurate and efficient regulation of indoor heating and cooling systems. When it comes to indoor temperature, distributed IoT devices in buildings can enable more accurate temperature forecasting and eventually help to build administrators in regulating the temperature in an energy-efficient way, but without damaging the indoor environment quality. While the IoT technology shows potential as a complement to HVAC control systems, the majority of existing IoT systems integrate a remote cloud to transfer and process all data from IoT sensors. Instead, the proposed IoT system incorporates the concept of edge computing by utilizing small computer power in close proximity to sensors where the data are generated, to overcome problems of the traditional cloud-centric IoT architecture. In addition, as the microcontroller at the edge supports computing, the machine learning-based prediction of indoor temperature is performed on the microcomputer and transferred to the cloud for further processing. The machine learning algorithm used for prediction, ANN (Artificial Neural Network) is evaluated based on error metrics and compared with simple prediction models.
Ri-leggere le Scritture al crocevia di pi� tradizioni. Per un pluralismo inter-intraculturale: tra simbolo e dialogo
Creators: name: VACCHELLI, Gianni
Publisher: name: Universit� degli studi di Bergamo
Year: 2014

description: The point of departure of the present study is the possibility of a secular, pluralistic, symbolic, inner reading of the Bible at the crossroads of multiple traditions: in primis Christian and Hebrew traditions (with references to Islamic mysticism) engaged in dialogue with the Orient (above all, the Indian advaita, with references to other Southeast Asian genres of wisdom literature).
There is undoubtedly a highly theoretical and speculative dimension to this research: philosophical hermeneutics, Biblical exegesis, literary and stylistic aspects, literary genres, philology, the anthropological and symbolic dimension and other forms of humanistic knowledge are involved. Attention must also be devoted to the paradigm of cultural rights, which lie at the crossroads of various disciplines (law, philosophy, anthropology, political science and economics, theology, etc.)
For that matter, the purpose of this project is also highly educational, political (in the sense of polis, of course), formative and cultural (Touraine), and is bound up with the vital turning points of our times, like interreligious and intrareligious dialogue, interculturality and intraculturality, the culture of human rights, the question of peace, pluralism and identity. However, it also hinges on religious phenomena, the �dynamite of the people� (J. Assmann), yet also has an extraordinarily transformational appeal, allowing translation and ?translatability? , dialogue and the concentration of values and symbols. All of these are central themes in international cooperation.
The Bible is, of course, a profoundly entrance- and performance-enabling work : it calls us to action, to change or to profundity, regardless of what our beliefs or our culture might be. The Biblical message has lay, secular value; it is open to everyone, and imparts wisdom. It is written: Lek leka (Gen 12,1; 22,2), which can also be translated as: �Go to yourself� .
In the present doctoral dissertation, hermeneutics is not only explained theoretically and philosophically, but also through exercises in reading, that is to say, robust exegetics of many famous, important passages (e.g., the first three chapters of Genesis, Abraham?s leaving his family (Gen 11-12), pages from Mark where Christ embraces children, etc.) The theme of the initiatory voyage, of divine names, of Panikkar?s cosmotheandric intuition, is researched in many Biblical passages.
The cultural and educational role of the Bible in the schools and in education is also highly significant. More attention should be devoted to the relationship between the Bible and human and cultural rights. Starting with the absence of the Bible as the �Great Code� of Western Civilization in the Italian schools, the present study shows how access to such a fundamental work is truly a cultural right in the hermeneutic methods described here.
THE ROLE OF CD133 IN THE IDENTIFICATION AND MAINTENANCE OF CANCER STEM CELLS DERIVED FROM HUMAN GLIOBLASTOMA
Creators: name: BRESCIA, PAOLA
Publisher: name: Universit� degli Studi di Milano
Year: 2012

description: Glioblastoma multiforme (GBM) is the most common and lethal type of brain tumor in adults. There are some evidences that it is maintained by a population of cells, namely cancer stem cells, able to self-renew and propagate the tumor. Despite recent advances in surgical and therapeutic treatment, no tangible improvements have been made to prolong the patients? survival.
The role of the cell surface CD133 as a cancer stem cell marker in brain tumors has been widely investigated, since it identifies cells within glioblastomas able to initiate neurosphere growth and form heterogeneous tumors when transplanted in immune-compromised mice. However, evidences of CD133-negative cells exhibiting similar properties have been reported, making definitive conclusions on the correlation between tumor-initiating capabilities of glioma stem cells and CD133 expression difficult to drawn. Moreover, the functional role of CD133 in cancer stem/progenitor cells is not known.
We analyzed the efficiency of CD133 in the identification and isolation of glioblastoma stem cells and we investigated its functional role, studying the biological effects of CD133 down-regulation in GBM-derived neurospheres in vitro and in vivo.
We observed that CD133 is homogenously expressed in the cytoplasm of the cells composing the neurospheres, while its expression on the cell surface is highly variable. Cloning of single CD133-positive and CD133-negative cells demonstrated that CD133 shuttles dynamically between the plasmamembrane and the cell cytoplasm and no hierarchical relation can be established.
Knockdown of CD133 by lentiviral-mediated short hairpin RNAs (shRNA) reduces the self-renewal and tumorigenic capacity of the GBM-derived neurosphere cells.
Taken together, our data suggest that cell surface CD133 is not useful for the isolation of glioblastoma stem cells, since a complex regulation of its expression in terms of protein levels and cellular localization exists. However, CD133 may contribute to the maintenance and the tumorigenic potential of glioblastoma stem cells. This implies that CD133 could be used as a therapeutic target in glioblastomas, regardless of its expression on cell surface.
sj-pdf-1-pps-10.1177_1745691621997530 – Supplemental material for The Rise, Demise, and Reprise of the Increasingly Protracted APA Journal Article?
Creators: name: Webster, Gregory D.
name: Wongsomboon, Val
name: Mahar, Elizabeth A.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, sj-pdf-1-pps-10.1177_1745691621997530 for The Rise, Demise, and Reprise of the Increasingly Protracted APA Journal Article? by Gregory D. Webster, Val Wongsomboon and Elizabeth A. Mahar in Perspectives on Psychological Science
The impact of the ELIXIR community in machine learning
Creators: name: Psomopoulos, Fotis
name: Capriotti, Emidio
name: Rosinach, Núria Queralt
name: Cirillo, Davide
name: Castro, Leyla Jael
name: Tosatto, Silvio
name: Members, The ELIXIR ML Focus Group
Publisher: name: F1000 Research Limited
Year: 2024

description: With the continuous generation, processing, and transformation of biological data, the application of Machine Learning (ML) has become one of the most effective approaches for extracting insights from this data and supporting decision-making processes. The ELIXIR Machine Learning Focus Group launched in October 2019, specifically to capture the emerging needs in ML expertise across the community, and has been consistently producing high-impact outputs over the past 5 years. Its overarching goals include all aspects of ML, from standards and reproducibility, to benchmarking and training.

One key output of the FG is the publication of the DOME recommendations (Nat Methods, July 2021), a set of community-wide recommendations for reporting supervised ML-based analyses of biological studies. Broad adoption of these recommendations help improve ML assessment and reproducibility. They have been effectively used in a more ambitious Strategic Implementation Study, leading to a coherent registry around DOME and a community-led publication annotation effort.

Another key activity of the FG aims to tackle challenges of synthetic data, creating frameworks and best practices for the generation, evaluation, and application of synthetic data. Achievements include a synthetic data catalogue, a FAIR metadata model, a data registry, an evaluation metrics review, and a community survey. 

Finally, as AI-ready data are a necessity in ML, a comprehensive effort around gold standard datasets is in place, collecting both paper candidates with datasets on selected domains (e.g. metabolomics/omics), as well as collected datasets that can be applied in ML in Life Sciences, specifically for supervised learning, around omics.
sj-pdf-1-gpi-10.1177_13684302211042417 – Supplemental material for Evoking gender distinctiveness threat in cisgender women lowers their support for gender-inclusive bathroom policies
Creators: name: Hayes, Talia R.
name: Reiman, Anna-Kaisa
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-1-gpi-10.1177_13684302211042417 for Evoking gender distinctiveness threat in cisgender women lowers their support for gender-inclusive bathroom policies by Talia R. Hayes and Anna-Kaisa Reiman in Group Processes & Intergroup Relations
THE IMPACT OF DIETARY FIBER AND SUCROSE ALTERNATIVES ON TEXTURE PERCEPTION OF COOKIES
Creators: name: Pitts, Sarah L
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Food chemistry and food sensory science

description: Low moisture baked goods (cookies, biscuits, etc.) are known for their high sugar content, low water content, and characteristic texture. The added sugar in baked goods has been a concern of health advocates due to the negative health implications of overconsumption of sugar. To minimize these health implications and support healthier food products, the replacement of sugar, sucrose, in low moisture baked goods with alternative sweeteners is of interest. The goal of this study was to improve understanding on how sweetener alternatives and dietary fiber interact with cookie ingredients and the subsequent cookie texture compared to sucrose containing cookies to aid in developing health-conscious low moisture baked goods. The replacement of sucrose with sucrose replacers (SRs) encompassing a variety of structural and physicochemical properties (high fructose corn syrup (HFCS), amorphous sucrose, maltitol, allulose, isomalt, Benefiber, Miralax, fructooligosaccharides (FOS), and isomalto-oligosacchrides (IMO)) in wire-cut cookies was investigated in terms of starch thermal properties, model cookie formulations, and sensory descriptive analysis. Starch thermal properties were investigated using differential scanning calorimetry (DSC) while wire-cut cookie parameters were analyzed through aw, color (a, b, L), moisture loss, cookie dimensions (height, width, length), and cookie hardness (N) assays. Sensory descriptive analysis was used to ascertain texture perception of wire-cut cookies through five attributes (hardness, fracturability, pastiness, cohesiveness, and crumbliness). The onset gelatinization temperature (Tgel) was increased to a greater extent than sucrose by Miralax and FOS, and to the same extent by IMO, maltitol, and Benefiber at high concentrations (60%w/w). The SRs which performed similar to sucrose in wire-cut cookie baking (spread, moisture loss, hardness) and texture intensity ratings were amorphous sucrose, maltitol, and allulose. No significant differences in descriptive analysis intensity scores were found in crumbliness, cohesiveness, and pastiness between SRs and sucrose formulated wire-cut cookies. FOS, IMO, and Benefiber displayed significantly larger fracture intensity scores compared so sucrose and isomalt cookies were significantly less hard than sucrose cookies. Principal component analysis (PCA) related SRs effect on starch gelatinization, cookie baking properties, and descriptive analysis intensity scores, and indicated the mostly likely candidates for use in reduced sugar cookies are maltitol and allulose.
Additional file 1 of Patients’ perspectives on quality and patient safety failures: lessons learned from an inquiry into transvaginal mesh in Australia
Creators: name: Motamedi, Mina
name: Degeling, Chris
name: M. Carter, Stacy
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Fast Algorithms for generating Minimal Rank H2-matrix for Electrically Large Surface Integral Operators
Creators: name: Yang, Chang
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Electrical engineering not elsewhere classified
Numerical and computational mathematics not elsewhere classified

description: Computational electromagnetics (CEM) plays an important role in many aspects of today's engineering world. Among existing CEM methods, Integral Equation (IE) based solvers are popular because of their versatility, efficiency, and reliability. IE-based methods in general result in a dense system matrix. To solve this system matrix efficiently, a prevailing solution is to use a Fast Multipole Method (FMM) with an iterative solver. Recently, fast H2-matrix based direct solvers have been developed to directly invert or factorize the dense system matrix. However, how to generate an H2-representation efficiently for electrically large analysis remains an unsolved problem. Existing methods for generating an H2-matrix of electrically large integral operators are all expensive, especially for surface IE (SIE) operators.
In this work, we proposed and developed a series of fast algorithms to generate a rank-minimized H2-matrix for electrically large SIE-based analysis, the best of which has complexity as low as O(NlogN) in time and memory. Using the H2-matrix generated in this work, we can make the H2-matrix-based direct solver achieve a total complexity of O(N1.5) in time and O(NlogN) in memory for electrically large SIE analysis. In contrast, generating an H2-matrix or inverting a dense matrix in a brute-force way both will cost O(N3) in time and O(N2) in memory. In addition to accelerating direct solvers, we significantly reduce the CPU time of a matrix-vector multiplication as well as the memory consumption because of the rank-minimized H2-representation. In addition to electromagnetic analysis, the proposed algorithms are applicable to many other disciplines, where a compact representation of dense matrices is the key to the reduction of computational complexity.
sj-docx-1-soq-10.1177_14761270211046870 – Supplemental material for Seeking input when the train has left the station: The decoupling of participative strategic decision-making processes and the role of new technology in symbolic management
Creators: name: Westphal, James D
name: Zhu, David H
name: Kunapuli, Rajyalakshmi
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business

description: Supplemental material, sj-docx-1-soq-10.1177_14761270211046870 for Seeking input when the train has left the station: The decoupling of participative strategic decision-making processes and the role of new technology in symbolic management by James D Westphal, David H Zhu and Rajyalakshmi Kunapuli in Strategic Organization
Positive Parenting and Adolescent Adjustment in Black, Hispanic, and White Families Facing Socioeconomic Adversity: A Resilience-Based, Two-Generation Approach
Creators: name: Nair, Nayantara
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Educational psychology
Family and household studies

description: Adversity stemming from socioeconomic risks poses a considerable threat to the wellbeing of parents and youth. Research has shown that children’s exposure to cumulative(consisting of multiple co-occurring risks), chronic(experienced across more than one timepoint), and early(experienced during the birth-to-three-year period) socioeconomic adversity is particularly detrimental to their development. The first aim of this dissertation was therefore to create a measure of socioeconomic adversity that incorporates multiple risk indicators, and that could be used to tap into both the chronicity and timing of exposure. Using this measure, the problem that this dissertation aimed to address is the conflicting evidence that effective parenting is crucial in facilitating positive outcomes in at-risk youth, but that parenting itself is severely compromised in families experiencing socioeconomic adversity. Therefore, the overarching goal of this dissertation was to identify protective factors that can be leveraged to promote positive cascades for parents and youth in the context of socioeconomic adversity. Paper 1 analyzed whether social capital facilitates parental resilience, or the capacity of parents to deliver competent and high-quality parenting to children despite the presence of socioeconomic risks. Paper 2 assessed whether positive parenting in turn facilitates adolescent resilience and well being, or the reduction of maladaptive outcomes and presence of flourishing outcomes despite their exposure to this adversity. Given differences in the experiences of socioeconomic adversity as well as its effects on parents and youth across race-ethnicities, a major goal of this work was to test dissertation aims separately within Black, Hispanic, and White families. Overall, Paper 1 findings suggest that social participation and perceived neighborhood control may attenuate the effects of socioeconomic adversity on positive parenting for Black and White mothers respectively. For Hispanic mothers, social cohesion was found to be a promotive factor for positive parenting in the context of socioeconomic adversity. Paper 2 results indicate that socioeconomic adversity is indirectly associated with higher levels of adolescent substance use in Black youth, and lower levels of adolescent wellbeing in White youth, through lowered self-regulation in middle childhood. However, higher levels of positive parenting in early and middle childhood seemed to weaken these negative effects within non-Hispanic families. These results reinforce the need to enhance social and neighborhood capital for parents facing socioeconomic adversity, in order to facilitate positive parenting behaviors that may in turn protect youth from its negative effects.
sj-docx-1-taj-10.1177_20406223211047304 – Supplemental material for Proteomic analysis of pulmonary arterial hypertension
Creators: name: Qin, Xiaohan
name: Li, Tianhao
name: Sun, Wei
name: Guo, Xiaoxiao
name: Fang, Quan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Respiratory Diseases

description: Supplemental material, sj-docx-1-taj-10.1177_20406223211047304 for Proteomic analysis of pulmonary arterial hypertension by Xiaohan Qin, Tianhao Li, Wei Sun, Xiaoxiao Guo and Quan Fang in Therapeutic Advances in Chronic Disease
Role of the geriatrician in the management of older patient with cancer = Il ruolo del geriatra nella gestione del paziente oncologico anziano
Creators: name: RUSSO, CHIARA
Publisher: name: Universit� degli studi di Genova
Year: 2019

description: The risk of cancer increases with age and the population growth will lead to an increased incidence of cancer in the elderly.
Presently, faced to emerging demands on health care, improvement of life expectancy, and concomitant development of procedures, this ?oncogeriatric? population requires specific clinical management.
Many specific issues may influence cancer treatment decision including the physicians' propensity to consider an old age as an obstacle to provide an optimal treatment, and to fear an increased disability and worsening of chronic conditions occurring with cancer and its treatment. Therefore it?s very important to stratify older patients according to their biological status, to be able to recommend the most appropriate type of treatment in a personalized fashion.
The optimal management should involve tumour assessment and careful geriatric evaluation.
Comprehensive Geriatric Assessment (CGA) provides an evaluation of the main geriatric domains, may assist in early identification of patients? strengths and weaknesses, geriatric problems requiring specific interventions, and may lead to the development of individual plans in order to facilitate cancer treatment program. Moreover, CGA should be seen as a dynamic tool able to progressively integrate new specific instruments to better assess the risk of treatment procedures.
However, the CGA is time and resource-consuming and requires the expertise of geriatricians. Thus, it remains poorly incorporated in routine clinical practice.
Consensus guidelines consider a ?two-step approach? as a reasonable strategy, where the first step involves a geriatric screening test to identify patients who are at high risk of being frail and the second step foresees a complete CGA to be performed by geriatricians.
A total of 17 different tools have been studied in 44 different trials to evaluate the best screening test in oncogeriatrics.
During my PhD I participated to several research projects in oncogeriatrics at the Policlinico San Martino, in Genoa, Italy, and at the Comprehensive Cancer Center L�on B�rard, in Lyon, France. Two studies were completed and published:
- Geriatric assessment in oncology: moving the concept forward. The 20 years of experience of the Centre L�on B�rard geriatric oncology program.
- Objectives: to explore the use of MGA in treatment decision and to identify MGA parameters likely to influence the planned cancer treatment.
- Performance of two frailty screening tools in older patients with solid cancer: a comparison of SAOP2 and G8.
- Objective: to compare the performance of two screening tools for frailty, G8 and Senior Adult Oncology Program (SAOP2) for their accuracy in identifying vulnerable patients.
The others studies are still in progress.
sj-docx-1-evp-10.1177_14747049211040823 - Supplemental material for Travel in the Physical and Mental Space: A Behavioral Assessment of the Phylogenetic Continuity Hypothesis Between Egocentric Navigation and Episodic Memory
Creators: name: Fragueiro, Agustina
name: Tosoni, Annalisa
name: Frisoni, Matteo
name: Di Matteo, Rosalia
name: Sestieri, Carlo
name: Committeri, Giorgia
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Anthropology
subject: FOS: Sociology
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-evp-10.1177_14747049211040823 for Travel in the Physical and Mental Space: A Behavioral Assessment of the Phylogenetic Continuity Hypothesis Between Egocentric Navigation and Episodic Memory by Agustina Fragueiro, Annalisa Tosoni, Matteo Frisoni, Rosalia Di Matteo, Carlo Sestieri and Giorgia Committeri in Evolutionary Psychology
COVER CROP IMPACTS ON NITROGEN CYCLING AND GRAIN PRODUCTION WITHIN CORN AND SOYBEAN CONSERVATION CROPPING SYSTEMS
Creators: name: Lacey, Corey G
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Agronomy

description: Cover cropping is an effective management practice for reducing nitrogen (N) losses to the environment from agriculture fields in the Midwest. Cereal rye (CR; Secale cereale L.) and hairy vetch (HV; Vicia villosa Roth) are two of the most common cover crop species grown in the region. However, limited cover crop adoption in the region is partly due to a dearth of knowledge addressing the effect of cover crops on nitrogen cycling and grain production within corn and soybean conservation cropping systems. The following studies were designed to address knowledge gaps in the current literature regarding the rate, quantity, and timing of cover crop residue C and N release; the fate of CR N following termination; and the effects of cover crops specifically on soybean growth, N assimilation, and yield. Data from this study revealed that growers should be aware that cover crop nutrient release may result in a “tug-of-war” between the soil microbiome and cash crops for soil inorganic-N. Additionally, we observed that CR N is used minimally by the subsequent crop; thus, growers should value CR N as a long-term benefit, such as building SOM. Finally, we found that added pressure from CR during early soybean growth may reduce soybean resilience, and in a wet year result in yield loss.
sj-docx-1-tan-10.1177_17562864211037430 – Supplemental material for Efficacy and tolerability of antiseizure drugs
Creators: name: Hakami, Tahir
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-1-tan-10.1177_17562864211037430 for Efficacy and tolerability of antiseizure drugs by Tahir Hakami in Therapeutic Advances in Neurological Disorders
sj-docx-1-jvm-10.1177_13567667211042641 - Supplemental material for How service quality and perceived value affect behavioral intentions of ecolodge guests: The moderating effect of prior visit
Creators: name: Ban, Joowon
name: Prideaux, Bruce
name: Kim, Hyoje Jay
name: Sheehan, Ben
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 150402 Hospitality Management

description: Supplemental material, sj-docx-1-jvm-10.1177_13567667211042641 for How service quality and perceived value affect behavioral intentions of ecolodge guests: The moderating effect of prior visit by Joowon Ban, Bruce Prideaux, Hyoje Jay Kim and Ben Sheehan in Journal of Vacation Marketing
Anthocyanins and polysaccharides interaction on gut barrier function
Creators: name: Fu, Wenyi
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Food sciences not elsewhere classified

description: Anthocyanin-containing foods are beneficial against chronic diseases. Anthocyanins exist as acylated and complexed with other macronutrients such as carbohydrates and proteins in the food matrix. Isolated anthocyanins are unstable and can be easily destabilized by environmental factors (pH, light, temperature). Furthermore, the colonic concentration of isolated anthocyanins is low compared to when in a food matrix. Complexation is a technique used to stabilize anthocyanins. This study aims to investigate which polysaccharides can stabilize the isolated anthocyanins from purple potatoes and enhance the colonic concentration of anthocyanins via complexation. The health benefits of anthocyanin-polysaccharide complexes were also evaluated in vivo. The different polysaccharides used were pectin, inulin, starch, cellulose, and their mixture in equal proportions. Pectin exhibited the best binding capacity with anthocyanins (anthocyanin-pectin complex; APC).
APC retained more anthocyanins compared to other complexes after the simulated upper GI digestion. The electrostatic interaction of APC quantified by zeta potential showed that anthocyanins were positively charged, and pectin was slightly negatively charged under pH 2.0 condition. The increased particle size of APC was observed indicating the agglomeration between particles. The physical surface structure of APC was changed after complexation compared to APM (anthocyanin-pectin mixture) as observed by SEM. The stability of anthocyanins in APC was better at pH 3, 5 and 7 and showed higher temperature tolerance than isolated anthocyanins. Furthermore, APC significantly decreased LPS-induced increase in gut permeability in Caco-2 cell model. APC restored the gut barrier function in vivo by reducing gut permeability and increasing mucus thickness in a DSS-induced colitis mouse model. APC also increased the total short-chain fatty acids especially butyrate concentration. In conclusion, APC enhanced the stability of isolated anthocyanins and improved the gut barrier function compared to isolated anthocyanins.