cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Sonnenfleckenzeichnung Nr. 22717.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.02.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Additional file 1 of Implementing community pharmacy-based influenza point-of-care test-and-treat under collaborative practice agreement
Creators: name: Hohmeier, Kenneth C.
name: McKeirnan, Kimberly
name: Akers, Julie
name: Klepser, Michael
name: Klepser, Stephanie A.
name: Chen, Christe
name: Klepser, Donald G.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Semi-Structed Interview Guide.
Design, modification of phyllanthone derivatives as anti-diabetic and cytotoxic agents
Creators: name: Nguyen, Ngoc-Hong
name: Vo, Van-Giau
name: Phan, Hoang-Vinh-Truong
name: Ngo, Thanh-The
name: Sichaem, Jirapast
name: Nguyen, Thi-Phuong
name: Nguyen, Huu-Hung
name: Pham, Duc-Dung
name: Nguyen, Tien-Cong
name: Nguyen, Van-Kieu
name: Duong, Thuc-Huy
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Twelve benzylidene derivatives, one Baeyer-Villiger oxidative, six imine derivatives were successfully designed and synthesised from phyllanthone. In the search for potential new anti-diabetic agents, phyllanthone along with its benzylidene and oxidation analogues were evaluated for enzyme inhibition against α-glucosidase. In the benzylidene series, most analogues displayed stronger activity than the mother compound. Compound 1c revealed the strongest activity, outperforming the acarbose positive control with an IC50 value of 19.59 µM. Phyllanthone and its derivatives were then tested for cytotoxic activity against the K562 cell line. The imine analogues displayed the most powerful cytotoxic activity with 3cand 3d having IC50 values of 57.55 and 68.02 µM, respectively.
Virion stiffness and human immunodeficiency virus type 1 entry
Creators: name: Pang, Hongbo
Publisher: name: University of Utah
Year: 2012
Subjects: Entry
HIV-1
Virion stiffness
Viral entry
Replication

description: After budding from infected cells, Human Immunodeficiency Virus type 1 (HIV-1) undergoes a maturation process that is required for viral infectivity. In the immature state, the major structural protein of viral particles, Gag, forms a thick protein shell underneath the viral membrane. During maturation, Gag is cleaved by HIV-1 protease and the resulting mature particles have a much thinner membrane-bound protein layer surrounding a conical core (capsid), which is a dramatic morphological change from the immature state. Employing atomic force microscopy (AFM), Itay Rousso's group together with ours previously discovered a dramatic change in particle stiffness during HIV-1 maturation mediated by the cytoplasmic tail (CT) of HIV-1's envelope protein (Env). A correlation between high particle stiffness and weak viral entry activity led us to investigate whether viral particle stiffness directly regulates viral entry activity.  First, after observing that standard viral purification conditions perturb virion structure and stiffness, we determined new purification conditions that preserve both. Next, we showed that CT alone is sufficient to regulate viral particle stiffness. This observation allowed us to independently increase particle stiffness using a construct that lacks the Env ectodomain and thus has no entry ability itself. Using this system, we showed that particle stiffness directly regulates the entry activity of the Env proteins of both HIV-1 and the unrelated Vesicular Stomatatis Virus (VSV). These results suggest a general role for particle stiffness in the regulation of viral entry, linking viral physical properties and biological functions. Mutagenesis studies reveal the important domains within CT or Gag that regulate viral entry activity. Employing an Env mutant with cleavable CT, we  obtained preliminary data about the timing of CT's regulation of particle stiffness. Taken together, these studies improve our understanding of viral structure and function during the viral lifecycle and suggest potential novel inhibitory strategies.
Impact of exercise programs on body mass index and waist circumference of individuals with Intellectual and Developmental Disabilities: a systematic review with meta-analysis
Creators: name: Jacinto, Miguel
name: Monteiro, Diogo
name: Antunes, Raul
name: Campos, Maria João
name: Ferreira, José Pedro
name: Matos, Rui
Publisher: name: Motricidade
Year: 2024

description: The global impact of physical activity and physical exercise on body mass index (BMI) and waist circumference (WC) in people with Intellectual and Developmental Disabilities (IDD), is not known, nor is the most effective type of exercise training for promoting these variables. The aim of this study was to assess the magnitude of the effect of physical exercise on BMI and WC in individuals with IDD through a systematic review with meta-analysis. Nine manuscripts met the eligibility criteria for the study. For BMI, the Z-value was Z=-2.176 and p=0.03. The highest magnitude of the effect was from the intervention with combined training showed the highest magnitude of effect (difference in means: -0.399, with a value of Z=-1.815 and p=0.07). For WC, the Z-value is Z=-3.306 and p=0.001. The intervention with continuous cardiorespiratory training showed the highest magnitude of effect (difference in means: -0.786, with a value of Z=-2.793 and p=0.005). Regular physical exercise seems to prevent an increase in BMI and WC in individuals with IDD. Similarly, the prescription of aerobic exercise seems to be more effective in promoting WC and the prescription of combined exercise in promoting BMI.
description: Motricidade, Vol. 20 No. S1 (2024): CIDESD International Congress 2023
Additional file 1 of An exploration of expectations and perceptions of practicing physicians on the implementation of computerized clinical decision support systems using a Qsort approach
Creators: name: Van Biesen, Wim
name: Van Cauwenberge, Daan
name: Decruyenaere, Johan
name: Leune, Tamara
name: Sterckx, Sigrid
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 1. Qsort vignettes.
A new diterpene and bioactivities of labdanes isolated from Buddleja marrubiifolia
Creators: name: Martínez-Pérez, Edith Fabiola
name: Burgueño-Tapia, Eleuterio
name: Roa-Flores, Samuel
name: Bendaña-Piñeiro, Aranza E.
name: Sánchez-Arreola, Eugenio
name: Bach, Horacio
name: Hernández, Luis Ricardo
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: The new labdane [(3R*,4aR*,7S*,10aS*,10bR*)-3-ethenyl-3,4a,7,10a-tetramethyl-dodecahydro-1H-naphtho-[2,1-b]-pyran-7-yl]-methylbenzoate together with other 7 labdanes were isolated from the aerial parts of Buddleja marrubiifolia. Compound structures were elucidated by spectroscopic methods. Some compounds showed moderate to weak antimicrobial activity towards a panel of bacterial and fungal pathogens. In addition, trans-biformene (2) and ribenol acetate (8) showed to be highly cytotoxic with LC50 < 1 µg/mL, the other compounds showed moderate cytotoxic effect with a LC50 range of 6.008–15.26 µg/mL. For all isolated compounds, no inflammatory response was observed.
Regulation of Uropathogenic Escherichia Coli Stress Response and Persistence in the Urinary Tract
Creators: name: Blango, Matthew George
Publisher: name: University of Utah
Year: 2014

description: Urinary tract infections (UTIs) afflict millions of individuals yearly, constituting a tremendous global health-care burden. The primary causative agents of UTIs are the gram-negative, rod-shaped bacteria, uropathogenic Escherichia coli (UPEC). These pathogens are motile and adhesive, with a proclivity to colonize diverse niches within the urinary tract; including the kidneys, bladder, and ureters. In the bladder, UPEC grow to high levels and often associate with the superficial epithelial cells lining the lumen. UPEC can invade these superficial epithelial cells to form intracellular reservoir populations, which are thought to be a source of recurrent, or relapsing, infections. The susceptibility of these intracellular UPEC populations was tested using a panel of commonly prescribed antibiotics in a murine model of UTI. Intracellular UPEC were found to persist despite treatment with host cell-permeable antibiotics such as sparfloxacin and ciprofloxacin that effectively sterilize the urine. In a follow-up study, UPEC reservoir populations were more effectively targeted by treating infected bladders with chitosan, a chitin-based bladder exfoliant, prior to sparfloxacin treatment. Although chitosan administration prior to antibiotic treatment significantly decreased UPEC titers, mice still exhibited some relapsing UTIs, suggesting that reservoirs still persist either within the bladder or in other host tissue. To further elucidate mechanisms of bacterial persistence within the urinary tract, several underappreciated bacterial factors were examined that were hypothesized to affect UPEC virulence, stress resistance, and persistence. iv Bacterial, small, non-coding RNAs (sRNAs) are posttranscriptional regulators of gene expression in most prokaryotes and were shown to contribute to a wide variety of UPEC stress response and virulence cascades. In a follow-up study, the putative UPEC sRNA repertoire was defined using RNA-Seq technologies and bioinformatic analyses. Several novel, candidate sRNA molecules were identified and characterized, one of which seemingly repressed UPEC virulence in the murine UTI model. In a second approach to define regulators of UPEC pathogenic behaviors, the tRNA modifying enzyme MiaA was identified as a global regulator of UPEC stress response and virulence. MiaA adds a prenyl group to A-37, adjacent to the anticodon, in a subset of tRNAs to modulate ribosome fidelity and frameshifting. MiaA expression in UPEC was responsive to several environmental stresses and deletion or overexpression of MiaA interferes with the stress resistance and virulence properties of UPEC. Taken together, this thesis defines the robust nature and resilience of intracellular UPEC reservoir populations and delineates sRNAs and MiaA as important regulators of stress resistance and persistence within the host.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.03.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Additional file 1 of Dementia patients in palliative care according to data from the German National Hospice and Palliative Care Register (2009–2021)
Creators: name: Donath, Carolin
name: Ostgathe, Christoph
name: Heckel, Maria
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Biotechnology
Cancer
Science Policy
Mental Health

description: Supplementary Material 1
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.01.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
A Comparison of Multicomponent and Concurrent Exercise Protocols on Muscle Strength in Older Adults
Creators: name: Rodrigues, Filipe
name: Matos, Rui
name: Jacinto, Miguel
name: Antunes, Raul
name: Monteiro, Diogo
name: Monteiro, Diogo
name: Amaro, Nuno
Publisher: name: Motricidade
Year: 2024

description: The objective of this study was to evaluate and compare the impact of a multicomponent exercise program and a concurrent exercise program on muscle strength among elderly individuals living in the community. Analysis using repeated measures ANOVA demonstrated significant main effects for the group factor (F(1,15) = 66.59, p < 0.001, η2 = .81) and the group*time factor (F(1,15) = 16.95, p < 0.001, η2 = .53) in relation to the 30-second chair test. For the 30-second arm curl, significant main effects were observed solely for the group factor (F(1,15) = 19.28, p < 0.001, η2 = .56). The timed up and go test revealed significant main effects for the group factor (F(1,15) = 35.56, p < 0.001, η2 = .70) and the group*time factor (F(1,15) = 11.68, p < 0.001, η2 = .43). Additionally, the group*time factor showed significant main effects for handgrip strength (F(1,15) = 5.19, p = 0.038, η2 = .25). The multicomponent exercise group exhibited a higher average increase compared to the concurrent exercise group. Although both exercise programs proved effective in enhancing muscle strength among elderly individuals living in the community, the multicomponent exercise group displayed superior outcomes across various physical fitness measures compared to the concurrent exercise group. These findings suggest that implementing a multicomponent exercise program may offer greater benefits for improving muscle strength in this specific population.
description: Motricidade, Vol. 20 No. S1 (2024): CIDESD International Congress 2023
COMPAS: a computeried patient advice system to direct ventilatory care
Creators: name: Sittig, Dean Forrest
Publisher: name: University of Utah
Year: 2012
Subjects: Biological
Monitoring, Physiologic
Respiratory Distress Syndrome, Adult
Respiratory Therapy

description: We have undertaken a randomized, controlled clinical trial to test a new form of respiratory support which includes Extracorporeal Carbon Dioxide Removal (ECC02R), against traditional continuous positive pressure ventilation for patients with Adult Respiratory Distress Syndrome (ARDS).  Since the experimental procedures were complex, detailed treatment protocols were developed by the clinical and research staff to describe monitored variables, frequency of data acquisition, decision logic (treatment protocols), and appropriate respiratory care for all modes of respiratory support in the clinical trial.  The treatment protocols had the potential to make the clinical approach to patients more uniform by equalizing the frequency of monitoring and the intensity of care for clinical trial patients.  The treatment protocols were converted into computer logic and implemented as a data driven COMputerized Patient Advice System (COMPAS) using a blackboard control architecture within the HELP clinical information system.  COMPAS automatically prompted the clinical staff with ventilator or extracorporeal circuit adjustment advice when new observational respiratory therapists, nurses, or members of the radiology, pharmacy, or the blood gas laboratories.  Following the availability of new data, COMPAS's therapy suggestions were available at the patient's bedside computer terminal in 2.2 minutes (avg.) (n = 3988) (82.3% available in under 2 minutes).  After 624 hours of patient care on the first 5 patients in the controlled clinical trial, the clinical staff carried out 84.4% of the computer generated therapy suggestions (320 of 379).  In situations which clearly suggested a therapy reduction, (Fi02 ? 90 mmHg) patients treated with COMPAS therapy suggestions had their Fi02 reduced more promptly (46.7 ± 51 minutes (mean ± SD) n = 20 for COMPAS patients vs 102.6 ± 91 minutes n = 2433 for patients treated in the traditional manner, p < 0.05).  The high compliance with COMPAS ventilatory therapy suggestions (88.4%) showed that the respiratory management of complex ARDS patients can be accomplished using COMPAS's computerized medial logic.  Both the frequency of monitoring and the intensity of patient care within the clinical trial were more uniform after COMPAS was implemented, thus enhancing the standardization of respiratory care crucial to the interpretation of the results of our clinical trial.
Talaromydien a and talaroisocoumarin A, new metabolites from the marine-sourced fungus Talaromyces sp. ZZ1616
Creators: name: Ma, Mingzhu
name: Yi, Wenwen
name: Qin, Le
name: Lian, Xiao-Yuan
name: Zhang, Zhizhen
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: 60506 Virology

description: New talaromydien A (1) and talaroisocoumarin A (2), together with nine known compounds (3 − 11), were isolated from a culture of the marine-derived Talaromyces sp. ZZ1616 in potato dextrose broth medium. Structures of the new compounds were elucidated based on their HRESIMS data, NMR spectroscopic analyses, the modified Mosher′s method, ECD, 13C NMR and optical rotation calculations. Talaroisocoumarin A showed antimicrobial activities with MIC values of 36.0 μg/mL against methicillin-resistant Staphylococcus aureus, 32.0 μg/mL against Escherichia coli, and 26.0 μg/mL against Candida albicans.
A-type potassium current in adult mouse olfactory receptor neurons.
Creators: name: Han, Pengcheng
Publisher: name: University of Utah
Year: 2012
Subjects: Mice
Channel Blockers

description: Voltage-gated potassium channels are important regulators of neuronal excitability, determining resting potentials, repolarizing action potentials and modulating sensory plasticity. In mammalian olfactory receptor neurons (ORNs), odor stimulated excitation is modulated by voltage-gated ion channels including potassium channels. In this study, ORNs from adult Swiss-Webster mice were acutely dissociated and cultured them in vitro. Depending on culture conditions, a relatively large inactivating potassium current (I A ) and relatively small noninactivating potassium current were present in adult mouse ORNs. Pharmacologically, the inactivating component was blocked by 4-aminopyridine (4-AP) and a peptide blocker rAa1. RT-PCR, immunohistochemical and immunoblot studies showed that I A of mouse ORNs contained the Kv1.4, Kv4.2 and Kv4.3 subunits, which belong to the A-type subfamily of voltage-gated potassium channels. Interestingly, in long term cell culture, the I A was downregulated by prosurvival peptide PACAP in parallel with a reduction in caspase activity. The reduction in caspase activity was mimicked by blocking I A with 4-AP, suggesting an important role of I A in cell apoptosis and survival. The reduction of I A by PACAP depended on the PLC intracellular signaling pathway and involved both a downregulation of genetic expression (Kv1.4 and Kv4.2 but not Kv4.3) and a direct functional modulation of the channels. In addition, calcium imaging showed that selectively blocking I A with the peptide blocker rAa1 prolonged the calcium response in ORNs, thus I A can be regarded as a temporal modulator. However, blocking I A with 4-AP unexpectedly reduced the calcium response probably due to initiation of a calcium-dependent feedback inhibition. These observations suggest that I A plays both physiological and pathophysiological roles in olfactory system, that reduction of I A is a crucial mechanism for the anti-apoptotic effect of PACAP, and that different I A antagonists may have contrasting biological effects.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.02.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.02.1968, erstellt von D. am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Additional file 1 of Translation, cross-cultural adaptation, and psychometric validation of the Malay version of the Assessment of Quality of Life—6 Dimensions (Malay-AQoL-6D) instrument among Malaysians living with chronic heart failure
Creators: name: Tan, Yi Jing
name: Ong, Siew Chin
name: Goh, Sook Pin
name: Chen, Gang
name: Yong, Vee Sim
name: Khor, Wei Wern
name: Kan, Ying Min
name: Choong, Yong Ying
name: Zameram, Ainul Mardhiyyah
name: Tan, Lin Yuing
name: Voo, James Yau Hon
name: Lam, Kar Kei
name: Yen, Chia How
name: Wahab, Mohamed Jahangir Abdul
name: Abdulla, Zarina Banu
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Supplementary Material 1
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.02.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.03.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Additional file 2 of An exploration of expectations and perceptions of practicing physicians on the implementation of computerized clinical decision support systems using a Qsort approach
Creators: name: Van Biesen, Wim
name: Van Cauwenberge, Daan
name: Decruyenaere, Johan
name: Leune, Tamara
name: Sterckx, Sigrid
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 2. Factor Scores with Corresponding Ranks.
Additional file 3 of An exploration of expectations and perceptions of practicing physicians on the implementation of computerized clinical decision support systems using a Qsort approach
Creators: name: Van Biesen, Wim
name: Van Cauwenberge, Daan
name: Decruyenaere, Johan
name: Leune, Tamara
name: Sterckx, Sigrid
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 3. Factor Matrix with Defining Sorts Flagged.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.03.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Automated patient query for use in pulmonary medicine
Creators: name: Rowe, Kerry Gene
Publisher: name: University of Utah
Year: 2012
Subjects: Medicine - Data processing
Medical records - Data processing

description: The focus of this research is the acquisition of patient history data and the use of these data by a hospital information system. There currently exists at LDS Hospital a comprehensive computer system designed to acquire and process medical data. There is a wide variety of information collected by the computer and stored in the patient database. However, some information fundamental to patient care is absent from the patient database. This information is the patient clinical history.  This project was designed to create a system in which clinical history information can be collected directly from a patient and easily entered into the computer. The questionnaire concentrated mainly on pulmonary medicine. A two-stage paper questionnaire, with the second stage produced by the computer, was completed by the patient. The paper format was chosen to allow the patient to easily complete the questionnaire, while the two stages provided the ability to use the computational and analytical power of the computer to direct the questioning. The information obtained from the history was used by the medical decision making programs of the LDS Hospital information system to diagnose the patient's illness.  There have been previous methods for history collection tested at LDS Hospital, which were more complex and longer than the two-stage method. The two-stage  questionnaire was designed to be as accurate as these other methods without asking as many questions or taking a great deal of the patient's time to complete the questionnaire. The success of the questionnaire system was measured in a variety of ways. The two-stage paper questionnaire was compared with these other methods in the areas of number of questions the patient was asked, the time required to complete the questionnaire and the accuracy of the diagnostic logic of the computer.  The two-stage questionnaire was able to substantially reduce the number of questions that the patient needed to answer and also reduce the amount of time required to complete the questionnaire. The diagnostic accuracy of the medical decision programs of the computer was similiar to the results obtained from a greater number of questions.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.02.1968, erstellt vermutlich von Sebestova am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Additional file 4 of An exploration of expectations and perceptions of practicing physicians on the implementation of computerized clinical decision support systems using a Qsort approach
Creators: name: Van Biesen, Wim
name: Van Cauwenberge, Daan
name: Decruyenaere, Johan
name: Leune, Tamara
name: Sterckx, Sigrid
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 4. Factor Q-sort Values for Statements sorted by Consensus vs. Disagreement.
Additional file 1 of GWAS-based polygenic risk scoring for predicting cerebral artery dissection in the Chinese population
Creators: name: Zhang, Shufan
name: Zhu, Dongliang
name: Wu, Zhengyu
name: Yang, Shilin
name: Liu, Yuanzeng
name: Kang, Xiaocui
name: Chen, Xingdong
name: Zhu, Zhu
name: Dong, Qiang
name: Suo, Chen
name: Han, Xiang
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 1
Toward a theory of professional support for parents of young adult schizophrenics
Creators: name: Park, Marilyn McKay
Publisher: name: University of Utah
Year: 2012
Subjects: Mentally ill - Family relationships
Schizophrenics
Supportive psychotherapy

description: This research project is viewed as one step in the development of a theory of professional support for families of chronically mentally ill patients.  The clinical problem for this project concerns the reality that parents of young adult schizophrenics have a role as primary caregivers; however, they live with enormous psychological, social, and economic stresses and lack sufficient information and skill to manage systems and behaviors effectively.  Parents often lack sufficient social support for themselves to alleviate their own distress, which interferes with their ability as caregivers.  The above information was available from surveys of members of family support groups.  The research problem was that not enough is know about the experience over time of parents who do not tend to join support groups.  In order to suggest a theory of professional support, more specific information on what types of help for which types of problems at what stages of this chronic disease was needed.  Professional support by psychiatric mental health nurses and other mental health professionals might distress experienced by parents and assist parent to provide more effective support for their young adult.  Parents of young adult schizophrenics were asked about their experience with potentially supportive people, including nurses and other professionals.  The subject described experience in their own words during interviews conducted at their homes.  The findings indicate the parents need additional information and professional support in order to be more effective caregivers.  The elements of professional support for parents which are recommended include: (1) a continual professional relationship with parents from the onset of the disease, (2) an esteem for and recognition of parents as a primary caregiver with mutual obligations in the treatment process, and  (3) a process of informing parents about the disease, behavior management, and medications which may enable parent to gain more control of stressful situations and become more effective decision-makers.
Additional file 5 of An exploration of expectations and perceptions of practicing physicians on the implementation of computerized clinical decision support systems using a Qsort approach
Creators: name: Van Biesen, Wim
name: Van Cauwenberge, Daan
name: Decruyenaere, Johan
name: Leune, Tamara
name: Sterckx, Sigrid
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 5. Factor Q-sort Values for Statements sorted by Consensus vs. Disagreement.
Characterisation of teaghrelin-like principles from Assam tea cultivated in Thailand
Creators: name: Li, Yue-Chiun
name: Tanapichatsakul, Chutima
name: Pripdeevech, Patcharee
name: Hwang, Tsong Long
name: Kuo, Ping-Chung
name: Tzen, Jason T. C.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Teaghrelins were identified as unique acylated flavonoid tetraglycosides and firstly reported in Chin-shin oolong tea. In the present study, two new teaghrelin-like compounds (1 and 2) were purified and characterised from Assam tea varieties collected in Thailand. Their chemical structures were constructed by the spectroscopic and spectrometric analysis. These two teaghrelin-like compounds were also not supposed to exhibit significant ghrelin receptor affinity according to the structural comparison with those teaghrelin-like compounds previously reported. In addition, compounds 1 and 2 did not display notable anti-inflammatory activity in human neutrophils assay.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.01.1968, erstellt von Vasile Dinulescu, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Dendropaemon (Nigropaemon) nigritulus Genier and Arnaud 2016
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Dendropaemon
Dendropaemon nigritulus

description: Dendropaemon (Nigropaemon) nigritulus Génier and Arnaud, 2016
Dendropaemon (Nigropaemon) nigritulus Génier and Arnaud 2016: 54 (Brazil (NA))
Distribution. Guyana: Génier and Arnaud 2016: 54. Suriname: Génier and Arnaud 2016: 54; NZCS. French Guiana: Génier and Arnaud 2016: 54; Boilly et al. 2016: 94. Brazil (NA): Génier and Arnaud 2016: 54 (NA). Venezuela (EO): Génier and Arnaud 2016: 54 (EO). Other: Génier and Arnaud 2016: 54 (Colombia).
Subgenus RUTILOPAEMON Génier and Arnaud, 2016
Dendropaemon (Rutilopaemon) Génier and Arnaud 2016: 66
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 100, DOI: 10.5281/zenodo.3678492
A finite index subgroup of BN(OS) with infinite dimensional cohomology
Creators: name: Kelly, Brendan
Publisher: name: University of Utah
Year: 2014
Subjects: Cohomology operations
Homology theory
Group theory
Mathematics - Research

description: Let Fp be the  nite  eld with p elements, let S be a  nite nonempty set of inequivalent valuations on Fp(t), and let OS be the ring of S-integers. If Bn is the solvable, linear algebraic group of upper triangular matrices with determinant 1, then the solvable S-arithmetic group Bn(OS) has a  nite-index subgroup with in nite-dimensional cohomology group in dimension jSj.
Sonnenfleckenzeichnung Nr. 22689.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 01.01.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
PROBLEMS OF USING INVESTMENTS IN THE IMPLEMENTATION OF THE TOURISM DEVELOPMENT CONCEPT IN UZBEKISTAN AND RECOMMENDATIONS FOR THEIR SOLUTION
Creators: name: Mamayunusov, Temurbek
Publisher: name: Zenodo
Year: 2025

description: Increasing the pace of tourism development in Uzbekistan to the level of indicators specified in the concept requires the formation of an active investment-oriented economic environment in the sector. Only then can the existing huge potential in the tourism sector be realized and become a multiplier of the socio-economic development of the country and its individual regions. The article presents the author's recommendations on the problems of using investments in the implementation of the concept of tourism development in Uzbekistan and their solutions.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 08.01.1968, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt
A new triterpenoid saponin from Glinus oppositifolius
Creators: name: Phan, Thuy Thanh
name: M., Lien T.
name: Van Phung, Trung
name: Nguyen, Thu Thi Hoai
name: Huynh, Vinh N.
name: Ngo, Duong Thi Thuy
name: Nguyen, Kim Phi Phung
name: Nguyen, Tuyet Thi Anh
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: From the ethanol extract of Glinus oppositifolius, collected at Phu Yen province, Viet Nam, one new triterpenoid saponin (1) and four known compounds (2–5) were isolated. By means of NMR and HR-ESI-MS analyses, their structure was elucidated as 3-O-(β-D-xylopyranosyl-(1→3)-β-D-xylopyranosyl)spergulagenin A or glinusopposide V (1), glinusopposide L (2), spergulin B (3), vitexin (4) and astralagin (5). Two compounds (1–2) showed weak inhibitory activity against α-glucosidase.
Additional file 1 of Psychometric properties of the Fraboni scale of ageism (FSA) applied to long-term caregivers in nursing homes
Creators: name: Li, Jie
name: Dong, Ziyan
name: Xie, Wen
name: Yang, Liuqing
name: Qi, Xiaojing
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Environmental Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer
Science Policy

description: Supplementary Material 1
Phase constitution and mechanical properties of carbides in the Ta-C system
Creators: name: Hackett, Kenneth Robert
Publisher: name: University of Utah
Year: 2012
Subjects: Carbides
Tantalum alloys

description: Carbides in the Ta-C system were prepared by hot-pressing mixed powders of  TaC and Ta in C/Ta atomic ratios of TaCo.6, TaCo.7, TaCu.8, TaCo.9, and TaCi.o at 1800 °C  for 2 h. Rietveld analysis was performed on all compositions, and it was found that  TaCo.6 was a mixture of 21% hexagonal close packed (HCP) a-Ta2C and 79%  rhombohedral ^ - T a ^ - x , TaCo.7 was a mixture of 44.6% rhombohedral ^ - T a ^ - x and  55.4% face centered cubic (FCC) TaCy , TaCo.s and TaCo.9 were approximately 100% FCC  TaCy , and TaC 1.0 was approximately 100% TaC. The TaC and TaCy compositions,  produced were single phase with C/Ta ratios essentially the same as the starting nominal  compositions and densities exceeding 96.5% of theoretical. Grain size decreased with  increasing carbon deficiency from 1.0 to 0.8, with a corresponding increase in Vickers  hardness from 13.5 to 20.0 GPa. The flexural strength, however, decreased from 650 to  500 MPa due to a decrease in fracture toughness from 5.3 to 3.8 MPaVm. Fracture  toughness measured by single-edge-precracked-beam (SEPB) technique was  exceptionally high (12.7 ± 0.7 MPaVm) for the a-Ta2C and ^ - T a ^ . x composition with a  high weight percent of the ^ - T a ^ . x phase (~83 wt %). This disconnect between the  change in hardness and strength indicates that the toughened compositions may exhibit  R-curve behavior. Fracture surfaces were highly faceted with multiple cleavage crack  planes and steps for TaCo.6 and TaCo.7. It is possible that the cleavage planes correspond  to the stacking faults between the FCC and the HCP stacking layers within the stacking  sequence ABABCACABCBC of the ^ - T a ^ . x phase bridge cracks in the crack wake  with accompanying variations in local carbon concentrations fluctuating between TaCy  and a-Ta2C.
Posttranscriptional  Regulation of the Envelope in Escherichia Coli
Creators: name: Kulesus, Richard Russell
Publisher: name: University of Utah
Year: 2014

description: Prokaryotes make extensive use of posttranscriptional regulation to modulate diverse cellular processes such as central carbon metabolism, stress response pathways, and virulence determinants. Posttranscriptional regulation in Escherichia coli is mediated via two broadly characterized methods. The first utilizes small noncoding RNAs (sRNAs) which bind target mRNA transcripts to alter their stability and translation. Nearly all characterized sRNAs function jointly with an RNA chaperone protein, Hfq. The second method employs mRNA-binding proteins which directly mediate translational inhibition or activation upon mRNA targets. Posttranscriptional regulation by both methods was recently demonstrated important to pathogenesis by several bacterial organisms. This study addresses the role of posttranscriptional regulation in uropathogenic Escherichia coli (UPEC), the organisms responsible for the majority of urinary tract infections. Specifically, deletion of Hfq, an RNA chaperone required for many sRNA-mRNA interactions, strongly reduced infection in murine models of cystitis and pyelonephritis and virtually eliminated formation of UPEC intracellular bacterial communities (IBCs). The hfq mutant experienced severe sensitivities to membrane disrupting agents such as polymyxin B, reactive oxygen species (ROS) and reactive nitrogen species (RNS) during in vitro models of host innate immune function. These phenotypes mirrored those of a !E-deleted UPEC, suggesting Hfq's involvement in posttranscriptional regulation of virulence was largely exerted at the bacterial envelope. In addition, RNS-treatment of ! ! "#! UPEC resulted in posttranscriptional downregulation of CpxP, a periplasmic regulator of the Cpx envelope stress response pathway. This downregulation was dependent on carbon storage regulator A (CsrA), a protein posttranscriptional regulator, as overexpression of CsrB, an sRNA antagonist of CsrA function, was sufficient to prevent as well as overcome downregulation of CpxP by RNS. Overexpression of CpxP in the presence of RNS proved beneficial to growth, however, suggesting CpxP downregulation by urinary RNS may not just disrupt UPEC's envelope, but impair the Cpx pathway involved in its repair. Anti-nitrotyrosine immunoblotting and mass-spectrometry indicate nitrosation of CsrA at tyrosine 48, a residue immediately adjacent to the domain implicated in RNA interaction, possibly altering CsrA's binding properties. These results demonstrate posttranscriptional regulation assisting virulence, but also imply manipulation by the host to deter growth.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.02.1968, erstellt als erste Tagesaufnahme um 10 h 00 von André Koeckelenbergh, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Changes in attachment, affect, and cognition
Creators: name: Fagundes, Christopher P
Publisher: name: University of Utah
Year: 2012
Subjects: Attachment behavior
Affect (Psychology)
Cognition

description: Sixty young adults who had recently experienced a breakup were prospectively followed over a four-week period in order to access (a) the degree of change in individuals' conscious treatment and unconscious cognitive perceptions of ex-partners as attachment figures, (b) how these changes are associated with corresponding changes in  individual's breakup resistance and their emotional adjustment (c) whether changes in each of these domains is associated with the individual's attachment style, coping strategies, and post breakup behavior. Results showed that individuals unconsciously treated their ex-partner as an attachment figure after the breakup and desired to utilize their ex-partner as an attachment figure after the breakup more than they actually did.  Individual differences in attachment style were not associated with conscious detachment but highly anxious individuals showed less of a decline in unconscious cognitive responses to the ex-partner as an attachment figure. Rumination was associated with less change in depressive symptoms and distraction was associated with greater change in breakup resistance. Partner contact and sex with ex-partner was associated with less conscious detachment, while committing to a new relationship was associated with  greater unconscious detachment.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.01.1968, erstellt am Kandilli Observatorium Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Kandilli Rasathanesi, Çengelköy (Istanbul). Instrument: Refraktor Teleskop (Öffnung 200 mm, f = 3070 mm, projiziertes Sonnenbild D = 25 cm).
Instrumentennachweis gemäss Kandilli Observatory Istanbul, Report from Solar Institute, in: Solar Physics, 1968, Vol. 3, Issue 3, pp.491-492, DOI: https://doi.org/10.1007/BF00171622