cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Europe and Syria: Diplomacy, Law and War
Creators: name: O'Connell, Mary Ellen
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: diplomacy
subject: intervention
subject: law
subject: militarism
subject: peace
subject: war

description: European Papers - A Journal on Law and Integration, 2017 2(1), 15-21
description: I. Introduction. - II. A growing fascination with armed force. - III. Reviving the art of peace through law - IV. Conclusion.
description: The conflict in Syria is entering its sixth year with no clear end in sight. EU Member States have a choice - continue or even escalate military involvement or seek an effective path to peace. Member States cannot do both because military involvement violates international law. Seeking peace requires using the methods of diplomacy on the basis of adherence to international law. Six years of unlawful intervention has not worked. It is time to give peaceful settlement a real chance, something the EU and its Member States have hardly done to date.
Effect of single-pill irbesartan/amlodipine combination-based therapy on clinic and home blood pressure profiles in hypertension with chronic kidney diseases
Creators: name: Kobayashi, Ryu
name: Tamura, Kouichi
name: Wakui, Hiromichi
name: Ohsawa, Masato
name: Azushima, Kengo
name: Haku, Sona
name: Uneda, Kazushi
name: Ohki, Kohji
name: Haruhara, Kotaro
name: Kinguchi, Sho
name: Umemura, Satoshi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: We examined the efficacy of single-pill irbesartan/amlodipine combination-based therapy for 12 weeks in 20 hypertensive chronic kidney disease (CKD) patients, by evaluating self-measured home blood pressure (BP) profile. The single-pill irbesartan/amlodipine combination-based therapy decreased clinic BP and home BP (morning, evening, and nighttime BPs), and improved within-visit clinic BP variability, day-by-day home BP variability (morning and evening), and nighttime home BP variability. Furthermore, the single-pill combination-based therapy reduced albuminuria and exerted improved parameters of vascular function. These results indicate that this single-pill combination-based therapy may exert beneficial effects on clinic and home BP profiles as well as on renal and vascular damages, in hypertension with CKD.
Neil Hollander Literacy
Creators: name: Hollander, Neil
Publisher: name: figshare
Year: 2016
Subjects: subject: 190402 Creative Writing (incl. Playwriting)
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: The writer, film director and producer, journalist and sailor, Neil Hollander has a career that continues over a span of more than 60 years. Born on July 9, 1939, in Brooklyn, New York City, Hollander had a chance to live his life his in many different countries such as Costa Rica, Thailand, and France. Led by his adventurous spirit and passion for sailing the ocean, in 1984 he went on a three-year trip across the Pacific, sailing the open sea in a small sailboat with no engine. During this voyage he visited many distant sea ports, witnessing the process of vanishing of the sailors who were still making a leaving from the sea, relying solely on the old traditions. In order to capture the spirit of that long gone time, and share some of the stories, this trip was documented in a relatively short book The Last Sailors: The Final Days of Working Sail, and later he filmed a 2.5 hour video story documentary, narrated by Orson Welles. On his blog at Metaliteracy, Neil Hollander regularly posts his memories from those times, completed with stories of today’s process of evolving regarding the documentary and feature films.
Antimicrobial and antioxidant activities of a new metabolite from Quercus incana
Creators: name: Gul, Farah
name: Khan, Khalid Mohammed
name: Achyut Adhikari
name: Zafar, Salman
name: Akram, Muhammad
name: Khan, Haroon
name: Saeed, Muhammad
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: Phytochemical investigations of Quercus incana led to the isolation of a new catechin derivative quercuschin (1), along with six known compounds: quercetin (2), methyl gallate (3), gallic acid (4), betulinic acid (5), (Z)-9-octadecenoic acid methyl ester (6) and β-sitosterol glucoside (7) from the ethyl acetate fraction of methanolic extract of the bark. Compound 1 was screened for its antibacterial, antifungal and antioxidant potential. Antibacterial and antifungal activities of the compound were tested against different bacterial and fungal strains, employing the agar well diffusion methods. The antibacterial activity was the highest against Streptococcus pyogenes with 80.0% inhibition, while the antifungal activity of the compound was the highest against Candida glabrata with 80.5% inhibition. The results of the antioxidant activity indicated that the compound exhibited antioxidant activity comparable to that of standard, butylated hydroxyanisole (51.2 μg/10 μl versus 45.9 μg/10 μl).
Fragstuck Vber den Catechismum deß hochgelehrten Petri Canisii, neben Außlegung der Ceremonien der H. Meß, vnd mancherley nutzlichen Fragen von allen Zeiten deß Jahrs; Anno M.DC.XLIX
Creators: name: (:Unav)
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2023

description: Vorlageform des Erscheinungsvermerks: Getruckt zu München, bey Lucas Straub. Anno M.DC.XLIX. Jn Verlag Johann Wagners.
MATLAB code for running the full lifespan lens growth model from A full lifespan model of vertebrate lens growth
Creators: name: Šikić, Hrvoje
name: Yanrong Shi
name: Snježana Lubura
name: Bassnett, Steven
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: The mathematical determinants of vertebrate organ growth have yet to be elucidated fully. Here, we utilized empirical measurements and a dynamic branching process-based model to examine the growth of a simple organ system, the mouse lens, from E14.5 until the end of life. Our stochastic model used difference equations to model immigration and emigration between zones of the lens epithelium and included some deterministic elements, such as cellular footprint area. We found that the epithelial cell cycle was shortened significantly in the embryo, facilitating the rapid growth that marks early lens development. As development progressed, epithelial cell division becomes non-uniform and four zones, each with a characteristic proliferation rate, could be discerned. Adjustment of two model parameters, proliferation rate and rate of change in cellular footprint area, was sufficient to specify all growth trajectories. Modelling suggested that the direction of cellular migration across zonal boundaries was sensitive to footprint area, a phenomenon that may isolate specific cell populations. Model runs consisted of more than 1000 iterations, in each of which the stochastic behaviour of thousands of cells was followed. Nevertheless, sequential runs were almost superimposable. This remarkable degree of precision was attributed, in part, to the presence of non-mitotic flanking regions, which constituted a path by which epithelial cells could escape the growth process. Spatial modelling suggested that clonal clusters of about 50 cells are produced during migration and that transit times lengthen significantly at later stages, findings with implications for the formation of certain types of cataract.
title: Les Ressources Éducatives Libres : rechercher, réutiliser, produire
Creators: name: Boussou, Cécile
Publisher: name: Centre de Coopération Internationale en Recherche Agronomique pour le Développement
publisherIdentifier: https://ror.org/05kpkpg04
publisherIdentifierScheme: ROR
Year: 2023

description: Les Ressources Éducatives Libres (REL) s’inscrivent dans le mouvement pour l’Éducation Ouverte. Pour l’Unesco, les REL sont «des matériels d'enseignement, d'apprentissage et de recherche sur tout support, numérique ou autre, existant dans le domaine public ou publiés sous une licence ouverte permettant l'accès, l'utilisation, l’adaptation et la redistribution gratuits par d'autres, sans restrictions ou avec des restrictions limitées.
Cette fiche développe les caractéristiques des REL, liste les bonnes pratiques pour en produire et propose une sélection de ressources pour trouver des REL en français en vue de les réutiliser.
Dikkat Eksikliği Hiperaktivite Bozukluğu (DEHB) Olan Çocukların Ebeveynlerinin Yaşadığı Psikososyal ve Davranışsal Sorunların İyileştirilmesi
Creators: name: Özer Z. G.
Publisher: name: Zenodo
Year: 2023
Subjects: DEHB, Nörogelişimsel Bozukluklar, Çocuk, Ebeveyn, Ebeveynlik Stresi, Kanıta Dayalı Müdahaleler, BPT

description: Bu çalışma OGB Project Sosyal Girişimi kapsamında oluşturulmuş bir uluslararası alanyazın tarama çalışmasıdır.

This article is an international literature review written by OGB Project Social Enterprise.
Decision Support Models for the Evaluation of Legume-Based Systems: Environment, Economy and Socio-policy
Creators: name: Debeljak, Marko
name: Dergan, Tanja
name: Squire, Geoff
name: Centofanti, Tiziana
name: Williams, Michael
name: Saget, Sophie
name: Styles, David
name: Costa, Marcela
name: Shailesh Shrestha
name: Toma, Luiza
name: Faical Akaichi
name: Balázs, Bálint
name: Kelemen, Eszter
name: Bienkowski, Damian
name: Hawes, Cathy
name: Iannetta, Pietro
name: Trajanov, Aneta
Publisher: name: Zenodo
Year: 2020
Subjects: Decision support
Legume
Food system
Multi attribute
Value chain

description: The series of decision models produced in this Deliverable (D8.2) will be integrated into a model for the assessment of overall sustainability of legume systems, with respect to the identification of key legume-based system indicators for the three pillars of sustainability. The decision model will be then used for evaluation of the relative sustainability of transition pathways to more effective scenarios.
Supplemental Methods from Caste-biased gene expression in a facultatively eusocial bee suggests a role for genetic accommodation in the evolution of eusociality
Creators: name: Jones, Beryl M.
name: Kingwell, Callum J.
name: Wcislo, William T.
name: Robinson, Gene E.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60408 Genomics
subject: 60801 Animal Behaviour

description: Detailed methods for sample collection, RNA preparation, library preparation, library sequencing, differential expression analyses, and overlap with other studies.
Table S1; Figure S1; Supplementary materials and methods; Supplementary discussion from Coral calcifying fluid pH is modulated by seawater carbonate chemistry not solely seawater pH
Creators: name: S. Comeau
name: E. Tambutté
name: R. C. Carpenter
name: P. J. Edmunds
name: N. R. Evensen
name: D. Allemand
name: C. Ferrier-Pagès
name: S. Tambutté
name: A. Venn
Publisher: name: The Royal Society
Year: 2016
Subjects: Environmental Science

description: Carbonate chemistry in the eight incubation tanks; Relationship between the relative calcification of S. pistillata and the ratio [DIC]/[H+]
Supporting Info: Nitrogen Biogeochemical Network from Organization of biogeochemical nitrogen pathways with switch-like adjustment in fluctuating soil redox conditions
Creators: name: Lamba, Sanjay
name: Bera, Soumen
name: Mubasher Rashid
name: Medvinsky, Alexander B.
name: Sun, Gui-Quan
name: Acquisti, Claudia
name: Chakraborty, Amit
name: Bai-Lian Li
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences
subject: 60114 Systems Biology
subject: 60199 Biochemistry and Cell Biology not elsewhere classified
subject: 69999 Biological Sciences not elsewhere classified

description: Nitrogen is cycled throughout ecosystems by a suite of biogeochemical processes. The high complexity of the nitrogen cycle resides in an intricate interplay between reversible biochemical pathways alternatively and specifically activated in response to diverse environmental cues. Despite aggressive research, how the fundamental nitrogen biochemical processes are assembled and maintained in fluctuating soil redox conditions remains elusive. Here, we address this question using a kinetic modelling approach coupled with dynamical systems theory and microbial genomics. We show that alternative biochemical pathways play a key role in keeping nitrogen conversion and conservation properties invariant in fluctuating environments. Our results indicate that the biochemical network holds inherent adaptive capacity to stabilize ammonium and nitrate availability, and that the bistability in the formation of ammonium is linked to the transient upregulation of the amo-hao mediated nitrification pathway. The bistability is maintained by a pair of complementary subsystems acting as either source or sink type systems in response to soil redox fluctuations. It is further shown how elevated anthropogenic pressure has the potential to break down the stability of the system, altering substantially ammonium and nitrate availability in the soil, with dramatic effects on biodiversity.
The Latin American Livestock Industry: Growth and Challenges
Creators: name: Williams, Gary W.
name: Anderson, David P.
name: Williams, Gary W.
name: Anderson, David P.
Publisher: name: Unknown
Year: 2020
Subjects: subject: Livestock Production/Industries
subject: Production Economics
subject: Deforestation
subject: Latin America
subject: Livestock industry
subject: Meat trade
subject: Poverty mitigation

description: The growing Latin American livestock industry supports widespread economic growth and contributes to poverty reduction and increased food security in the region. Tradeoffs abound in the attainment of economic growth versus environmental objectives.
Optimization of Wire Electrical Discharge Machining Process Parameters in AZ91 Magnesium Alloy Using Taguchi-Based Fuzzy Analytic Hierarchy Process (TFAHP) Method
Creators: name: Meshach Chukwuebuka Ikedue
Publisher: name: Faculty of Engineering Mahasasakham University
Year: 2024
Subjects: Optimisation
EDM process
Taguchi method
fuzzy AHP

description: Engineering Access, 10, 1, 6-20
Optimization Design of a V-shaped Flux Switching Permanent Magnet Traction motor for Railway Applications
Creators: name: Pattasad Seangwong
Publisher: name: Faculty of Engineering Mahasasakham University
Year: 2024
Subjects: permanent magnet motor
railway traction applications
flux-switching, sensitivity analysis
genetic algorithm optimization

description: Engineering Access, 10, 1, 21-27
Coupled Taguchi-Pareto-Box Behnken Design-Grey Wolf Optimization Methods for Optimization Decisions when Boring IS 2062 E250 Steel Plates on CNC Machine
Creators: name: Yakubu Umar Abdullahi
Publisher: name: Faculty of Engineering Mahasasakham University
Year: 2024
Subjects: Grey wolf optimisation
CNC machine
Taguchi-Pareto
fitness values
parameters

description: Engineering Access, 10, 1, 28-41
Detailed description of methods and results including figures S1 and S2 from Here and there, but not everywhere: repeated loss of uncoupling protein 1 in amniotes
Creators: name: McGaugh, Suzanne
name: Schwartz, Tonia S.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: A word document containing the detailed methods, figures S1 and S2, and the legends for supplemental tables S1-S30 in ESM file 2
Electronic Supplementary Material from A lognormal distribution of the lengths of terminal twigs on self-similar branches of elm trees
Creators: name: Koyama, Kohei
name: Yamamoto, Ken
name: Ushio, Masayuki
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Computational Biology
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: Tables S1 and S2
Supplementary information to: Food availability affects adult survival trajectories depending on early developmental conditions
Creators: name: Briga, Michael
name: Koetsier, Egbert
name: Boonekamp, Jelle J.
name: Jimeno, Blanca
name: Verhulst, Simon
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Food availability modulates survival in interaction with e.g. competition, disease and predators, but to what extent food availability in natural populations affects survival independent of these factors is not well known. We tested the effect of food availability on lifespan and actuarial senescence in a large population of captive zebra finches by increasing the effort required to obtain food, reflecting natural contrasts in food availability. Food availability may not affect all individuals equally and we therefore created heterogeneity in phenotypic quality by raising birds with different numbers of siblings. Low food availability had no effect on lifespan for individuals from benign developmental conditions (raised in small broods), but shortened lifespan for individuals from harsh developmental conditions. The lifespan difference arose through higher baseline mortality rate of individuals from harsh developmental conditions, and despite a decrease in the rate of actuarial senescence. We found no evidence for sex-specific environmental sensitivity, but females lived shorter than males due to increased actuarial senescence. Thus, low food availability by itself shortens lifespan, but only in individuals from harsh developmental conditions. Our foraging availability manipulation resembles dietary restriction as applied to invertebrates, where it extends lifespan in model organisms and we discuss possible reasons for the contrasting results.
title: Judicial Cooperation, Transfer of Prisoners and Offenders' Rehabilitation: No Fairy-tale Bliss. Comment on Ognyanov
Creators: name: Montaldo, Stefano
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: judicial cooperation in criminal matters
subject: enforcement of a sentence
subject: territoriality
subject: penalty
subject: more lenient national legislation
subject: offenders' rehabilitation

description: European Papers - A Journal on Law and Integration, 2017 2(2), 709-718
description: European Forum Insight of 16 July 2017
description: I. Better late than never: the first case concerning the Council Framework Decision 2008/909/JHA on the transfer of prisoners in the European Union. - II. Facts of the case. - III. The notion of enforcement of a sentence and the division of competences between the issuing and executing States. - III.1. Which enforcement? The applicable law in the light of the division of competences between national authorities. - III.2. Mutual recognition and the role of the national authorities. - IV. No fairy-tale bliss: is this just a watered down version of mutual recognition, to the detriment of a common approach to offenders' social rehabilitation?
description: This Insight analyses the first preliminary ruling (Court of Justice, judgment of 8 November 2016, case C-554/14, Ognyanov [GC]) concerning a provision of the Council Framework Decision 2008/909/JHA on the cross-border transfer of prisoners in the EU. The Court of Justice clarifies the notion of enforcement of the sentence, for the purposes of the horizontal division of competences between the issuing State and executing authority. In this context, despite the quasi-automatic nature of judicial cooperation mechanisms, a prominent role is given to the issuing authority. In particular, the issuing State is entitled to assess unilaterally the prisoner's chances of social rehabilitation abroad. It is contended that this prudent approach, albeit reasonably inspired by the well-established principle of territoriality of criminal law, is capable of undermining the effectiveness of the Council Framework Decision 2008/909. This approach also blocks a gradual emergence of a common European approach to offenders' social rehabilitation, which is a key objective of judicial cooperation in criminal matters. A common attitude towards crime prevention through offenders' rehabilitation could be the feeding ground favouring future evolution of cooperation in criminal matters, besides the current overarching focus on ex post crime repression.
Assessing the Impact of Groundwater Variability on Dam Safety Based on Flood Situation and Climate Change Scenarios Using Hydrological Model
Creators: name: Anongrit Kangrang
Publisher: name: Faculty of Engineering Mahasasakham University
Year: 2024
Subjects: dam safety
groundwater
runoff
SWAT
Lam Khan Chu Dam

description: Engineering Access, 10, 1, 65-72
Energy Efficiency Evaluation for Buildings with Solar Window Technology using BEC Codes of Thailand: Case Study of Skyscrapers in Nanning, China
Creators: name: Raohuai Liang
Publisher: name: Faculty of Engineering Mahasasakham University
Year: 2024
Subjects: Building energy codes
energy efficiency evaluation
solar window technology
solar energy

description: Engineering Access, 10, 1, 73-80
MPEC 2024-U228 : 2024 UE8
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 UE8

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Audit report study 1A
Creators: name: Filius, Renée
Publisher: name: figshare
Year: 2016
Subjects: Education

description: This is the audit report of the study “Challenges concerning deep learning in SPOCs” executed by Renée Filius with Rianne Bouwmeester as an auditor. To insure quality in all of the steps described, an audit trial has been created (Akkerman, Admiraal, Brekelmans & Oost, 2008). In this trial the first author will identify all steps of data gathering and analysis accompanied by theoretical justification for the decisions made. An independent researcher will conduct a formative audit. The report on the strengths and limitations of the study will serve as a starting point for the analysis description to realize transparency, as well as for issues that needed to be singled out as limitations in the conclusion session.
A Study of Picasso's Painting Materials and Techniques in Six of His Early Portraits
Creators: name: Clarimma Sessa
name: Garnica, Reyes Jiménez De
name: Rosi, Francesca
name: Fontana, Raffaella
name: Garcia, Jose Francisco
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Cell Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Six early portraits from 1895 to 1900/1 by Pablo Picasso were comprehensively examined using complementary non-destructive techniques provided by the MOLAB Transnational Access Service as part of the European Cultural Heritage Advanced Research Infrastructures (CHARISMA) project. The paintings were selected by the Museu Picasso, Barcelona, as representative of Picasso's formative years. This paper presents a compendium of the results from the extensive analysis campaign, which involved meticulous inspection of the stratigraphy of each portrait and elucidation of the palette used by the artist in his early career. Subsurface imaging (X-ray radiography and infrared reflectography) was used to guide analytical data interpretation. Prussian blue, cobalt blue, ivory black, lead white, natural earths, vermilion, chromium-based pigments, and different fillers were identified in the paintings. With this simple palette, Picasso was able to play with the colors to create different shades and tones. Careful inspection of the brushstrokes and material distribution highlighted important details, providing a better understanding of the creative process behind the portraits studied and young Picasso's modus operandi. Furthermore, all the portraits were found to have been painted over earlier compositions.
The Regulation of Nontypeable Haemophilus influezae-Induced Inflammation and an Alternative Therapeutic Strategy
Creators: name: Andrews, Carla
Publisher: name: Georgia State University
Year: 2016

description: Airway diseases such as asthma and chronic obstructive pulmonary disease (COPD) affect more than one-half billion people globally resulting in billions of dollars in healthcare costs and there are no cures. These diseases are characterized by excessive inflammation and are exacerbated by respiratory pathogens such as nontypeable Haemophilus influenzae (NTHi). While inflammation is necessary to eliminate a pathogen, excessive inflammation causes epithelial injury and airflow limitation. Therefore, the inflammatory response must be tightly regulated. The limited success of currently available pharmaceuticals used to manage these diseases presents an urgent need for the development of novel, non-antibiotic therapeutics. An alternative therapeutic strategy is to upregulate the negative regulators of inflammation. Understanding the regulation of these negative regulators is crucial to this alternative strategy. One such negative regulator that has not been widely studied is the alternative spliced short variant of myeloid differentiation factor 88 (MyD88) called MyD88 short (MyD88s). Studies show that phosphodiesterase (PDE) inhibitors have promising therapeutic potential. Resveratrol is a PDE inhibitor and is being widely studied for its anti-inflammatory effects. However, the molecular mechanisms underlying the clinical efficacy remain largely unknown. In this dissertation we first show that NTHi induces expression of MyD88s and MyD88s is a negative regulator of inflammation in bronchial epithelial cells and in the lung of mice. We further demonstrate that MyD88s is positively regulated by IKK? and CREB and negatively regulated by ERK1/2 signaling pathways. Next we show for the first time that resveratrol decreases expression of pro-inflammatory cytokines in vitro and in the lung of mice by enhancing NTHi-induced MyD88 short via inhibition of ERK1/2 activation. Furthermore, resveratrol inhibits NTHi-induced ERK1/2 phosphorylation by increasing MKP-1 expression via a cAMP-PKA-dependent signaling pathway. Lastly, we show that resveratrol has anti-inflammatory effects post NTHi infection, and therefore, its therapeutic potential is clinically significant. Together these data reveal a novel mechanism by which resveratrol alleviates NTHi-induced inflammation in airway disease by upregulating the negative regulator of inflammation MyD88s.
Assessment OF, FOR and AS Learning: Students as Partners in Assessment
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2016
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: Education

description: This Forum Insight aims to give both students and staff some initial thoughts on how they can facilitate students to become partners in the assessment process (Cook-Sather et al., 2014). It builds on the outputs of a workshop organised in partnership between the Union of Students in Ireland (USI) and the National Forum for the Enhancement of Teaching and Learning. It presents both ideas that students have some control over and ideas that staff could consider in their assessment designs.
An Introduction to the Learning Analytics and Educational Data Mining for Learning Impact Project
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2016
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: Education

description: This Forum Insight introduces the key concepts of learning analytics and educational data mining and summarises the National Forum’s Learning Analytics and Educational Data Mining for Learning Impact Project, which runs from September 2016 to June 2017.
NMBP-13 First Newsletter
Creators: name: NMBP_13 Projects
Publisher: name: Zenodo
Year: 2020

description: Welcome to the first newsletter fro the Gov4Nano, NANORIGO and RiskGONE initiatives - three H2020 projects that have joined forces to develop and establish a robust public policy framework for the use of nanomaterials based on scientific evidence supporting a clear understanding of risks, their assessment and management within wider societal considerations.
Modeling neuropathogenesis of B virus infection in the macaque ganglia
Creators: name: LeCher, Julia
Publisher: name: Georgia State University
Year: 2016

description: B virus is an alphaherpesvirus, endemic to macaque monkeys, capable of deadly human zoonosis with an 80% mortality rate in untreated cases. The macaque monkey is widely used in biomedical research and the threat of B virus poses an occupational hazard to researchers, veterinarians, and animal handlers. B virus establishes a life-long latent infection in sensory neurons of the peripheral nervous system (PNS) in the natural host. In human infections, B virus readily transits to the central nervous system (CNS) and destroys brain tissues. Identifying immune correlates of B virus infection in the PNS of the natural host is critical in understanding viral lethality in the human host. The lack of an accurate animal model and restrictions on handling potentially infected nervous tissue previously limited studies of B virus infection in macaque ganglia. To address this barrier, a long-lived mixed neuron/glia cell culture model was established from macaque DRG explants using a novel methodology that relied on cellular migration from whole tissues. Utilizing this model, the hypothesis tested was that acute B virus infection of macaque ganglia triggers cellular defense networks to promote leukocyte recruitment and impact leukocyte activation. Chemokines were upregulated in B virus-infected cultures and infected cell media induced leukocyte chemotaxis. Leukocytes were less effectively activated by media from infected cells when compared to media from mock-infected cells. To identify factors responsible for this, focused microarrays were performed and cytokine profiles were quantified from B virus and mock-infected culture supernatants. IL-6 protein levels were significantly reduced in B virus infected cultures. This observation led to the hypothesis that IL-6 downregulation impairs leukocyte activation and, indeed, when IL-6 was added to B virus-infected culture supernatants to control levels, these cultures were far more effective at eliciting leukocyte activation when compared with mock-infected cultures. Collectively, these data support the hypothesis that acute B virus infection of macaque ganglia triggers cellular defense networks to promote leukocyte recruitment and impact leukocyte activation and identifies a potential viral mechanism to impair leukocyte functionality. Additionally, this work presents a novel methodology for establishing long-lived mixed neuron/glia cultures from postnatal/adult macaque DRGs.
Common practices in transnational research, ICT case and challenges
Creators: name: Lazzeri, Emma
Publisher: name: Zenodo
Year: 2020
Subjects: Open Science
ICT
Open Software
Open Access
Funder Policies

description: This presentation was given by Emma Lazzeri at the CHIST-ERA Workshop on Open Science in Transnational Research, held in Bern, Switzerland, on March 6th The outline of the presentation are the following: - Why do we need Open Science? The researcher perspective
 This part highlights the benefit of Open Science from the researcher point of view. Not only it is a duty coming from the funders obligation, but it is also an opportunity for researchers. OS helps researchers to: Keep their research safe and secure, Increase research efficiency, Make research outputs more visible (curated data facilitate data sharing), Enable collaboration (within or outside the specific discipline)
 - Current practices in the ICT domain
 The use of GitHub to deposit software: what is GitHub and how it works. (Tool to manage your software, not to publish, no preservation, no fundability, no attribution)
 The link with Zenodo (to make your research-software "FAIR")
 Software Heritage. (An international initiative to preserve software)
 Software Journals. A way to publish software as research article
 - Replicate, Reproduce, Reuse
 What it means to replicate/reproduce/reuse ICT research
 The importance of linking Reser ch product. Publishing the research cycle also means to deposit all the items that made your research flow possible. It is therefore important to deposit and link related products/items as articles and datasets to make research reusable.
 - OpenAIRE: the EC funded infrastructure for OA
 What is OpenAIRE and how it works.
 What can OpenAIRE do to support funders and researchers in the path too Open Science as a default
 Takeaway messages for a Funder Policy
Tax Incentives in the State of Qatar
Creators: name: Al-Taweel, Fatima Abdulrahman W. M.
Publisher: name: Manara - Qatar Research Repository
Year: 2024
Subjects: classificationCode: 48
subject: Law and legal studies

description: Tax incentives are a common practice in the world designed to encourage and attract foreign investors to invest in a country by reducing the tax payment or to be exempt, these incentives have a vast positive impact economically, such as enhancing productivity and economic growth. However, nowadays, the negative impact is increasing day by day, tax base erosion is one of these negative impacts. Managing those incentives properly and having an efficient legal and administrative framework might be challenging. Internationally, there is an emerging agreement on the need to address the potential disadvantages of tax incentives for investment. The question that arises concerning tax incentives for investments in the State of Qatar relates to the governance of these tax incentives to investigate actions taken by the State of Qatar or in the State of Qatar about tax incentives for investment.
The integrated biomarker response: a suitable tool to evaluate toxicity of metal-based nanoparticles
Creators: name: Devin, Simon
name: Buffet, Pierre E.
name: Châtel, Amélie
name: Perrein-Ettajani, Hanane
name: Valsami-Jones, Eugénia
name: Mouneyrac, Catherine
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Nanotechnology is a much promising field of science and technology with applications in a wide range of areas such as electronics, biomedical applications, energy and cosmetics. Metal-based engineered nanoparticles (ENPs) are common in many technological applications; some of the most common nanoparticles available commercially are silver, gold, copper oxide (CuO), zinc oxide (ZnO) and cadmium sulphide (CdS). The toxicity of metal-based NPs may be either due to their specific physical characteristics as NPs or to the specific toxicity of metals released from NPs under environmental conditions. In this study we evaluated the toxicity effects of a range of ENPs (Ag, Au, CuO, CdS, ZnO) along with a control containing equivalent quantities of dissolved metal on two endobenthic species: the ragworm Hediste diversicolor and the bivalve Scrobicularia plana. A suite of complementary biomarkers was used to reveal toxicity effects. A common challenge in multibiomarkers studies is to go beyond an independent interpretation of each one, and to assess a global response of individuals. The Integrated Biomarker Response (IBR) was calculated for both species exposed to the different metal-based ENPs studied or to their dissolved metal counterpart to provide efficient and easy tools for environmental managers. We evidence that metal-based NPs lead to an overall difference in biological responses from that of their dissolved counterparts. The IBR could thus be considered as an efficient tool to transfer research results to stakeholders with possible implementation for regulatory purposes.
title: Positioning Efler in the Current Narrative of European Citizens' Initiatives
Creators: name: Inglese, Marco
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: European Citizens' Initiative
subject: STOP TTIP
subject: Efler
subject: EU legal acts
subject: negotiations of international treaties
subject: Commission's powers

description: European Papers - A Journal on Law and Integration, 2017 2(2), 749-758
description: European Forum Insight of 1 August 2017
description: I. Introduction. - II. An ECIs' overview. - III. The Efler case. - IV. Concluding remarks: an assessment and a step forward.
description: Efler (General Court, judgment of 10 May 2017, case T-754/14, Efler et al. v. Commission) is the last in a stream of cases dealing with the European Citizens' Initiative (ECI). This Insight seeks to position Efler in the current narrative of ECIs taking into account the Commission's powers - as well as the boundaries thereto - to register an ECI, in the light of the case law of the General Court. Therefore, this Insight will be structured as follows. Firstly, it will offer an overview of the current state of affairs regarding ECIs, with a particular emphasis on the case law of the General Court concerning the registration stage of an ECI. Secondly, it will tackle the peculiarity of the Efler case, to the extent that the General Court focussed on the concept of legal act to implement the Treaty. Thirdly and in conclusion, it will argue that Efler is a welcome development in the narrative of ECIs given that it could very well have a positive impact on the revision of Regulation 211/2011, making the registration procedure more citizen-friendly. However, the broad understanding of the notion of legal act offered by the General Court could even open the gates to a flow of unrealistic and unreasonable ECIs.
MYRTUS- Multi-layer 360° dYnamic orchestration and interopeRable design environmenT for compute-continUum Systems
Creators: name: Fanni, Tiziana
name: Zedda, Maria Katiuscia
name: Palumbo, Francesca
Publisher: name: Zenodo
Year: 2024

description: Started on January 2024, the MYRTUS Horizon Europe project aims at unlocking the new living dimension of Cyber-Physical Systems (CPS), embracing the principles of the TransContinuum Initiative, integrating edge, fog and cloud computing platforms. Orchestration mechanisms, programming languages, and tools need to be reinvented to master collaborative distributed and decentralised components. Additionally, components must be augmented with interface contracts covering both functional and non-functional properties. MYRTUS solutions play a crucial role in enabling sustainable computing and trustworthiness in CPS.
Transport Policies and Development
Creators: name: Berg, Claudia N.
name: Deichmann, Uwe
name: Yishen Liu
name: Selod, Harris
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: This survey reviews the current state of the economic literature, assessing the impact of transport investments and policies on growth, inclusion, and sustainability in a developing country context. It also discusses the specific implementation challenges of transport interventions in developing countries.
Salnykova, A., Vorobyova, A., Rouhani, S., & Hankivsky, O. (2016). Tobacco and Alcohol Consumption in Post-Soviet Ukraine: Qualitative Findings from Community Consultations
Creators: name: Salnykova, Anastasiya
name: Vorobyova, Anna
name: Rouhani, Setareh
name: Hankivsky, Olena
Publisher: name: figshare
Year: 2016
Subjects: subject: 111712 Health Promotion
subject: FOS: Health sciences

description: Salnykova, A., Vorobyova, A., Rouhani, S., & Hankivsky, O. (2016). Tobacco and Alcohol Consumption in Post-Soviet Ukraine: Qualitative Findings from Community Consultations. Tobacco Control and Public Health in Eastern Europe, 6(1), 1-19.
Can transport infrastructure change regions’ economic fortunes? Some evidence from Europe and China
Creators: name: Chen, Chia-Lin
name: Vickerman, Roger
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: Can transport infrastructure change regions’ economic fortunes? Some evidence from Europe and China. Regional Studies. Claims and counterclaims about the likely impact of new transport infrastructure on a region’s economic performance have existed for centuries going back to the early days of canals and railways. High-speed rail (HSR) as a new type of infrastructure has just over 50 years of existence. The persistent debate is questioning the power of HSR in reducing economic disparities between cities and effecting economic transformation. The paper goes beyond macro-modelling, looking to more disaggregated approaches of the structural changes. Two regions, one in Europe and one in China, are compared to gain insights for future research and practice.
Transcriptional Regulation of Factors Required for The Differentiation of Gabaergic Motor Neurons in the Developing Ventral Nerve Cord of Caenorhabditis Elegans
Creators: name: Campbell, Richard
Publisher: name: Georgia State University
Year: 2017

description: Development of the nervous system is a highly organized process that utilizes genetic mechanisms conserved across the animal kingdom. Components of the nervous system such as inhibitory GABAergic neural networks are common among most multicellular animals. The nematode Caenorhabditis elegans, utilizes similar genetic pathways to that of mice and humans to develop its GABAergic neural networks. These GABAergic neural networks are composed of two types of GABAergic motor neurons: the VD and DD sub-classes. The GABAergic differentiation of both these sub-classes requires the conserved transcription factor, Pitx/UNC-30. The VD sub-class is differentiated from the DD motor neurons by the expression of another transcription factor, COUP TFII/UNC-55. The transcriptional mechanisms regulating the expression of Pitx/UNC-30 and Coup TFII are unknown. We sought to determine how Pitx/UNC-30 and COUP TF-II/UNC-55 were transcriptionally regulated in an attempt to understand how mechanisms of GABAergic fate specification and class specification may be connected. We hypothesized there would be different mechanisms regulating the GABAergic differentiation and sub-class specification of the two sub-classes of GABAergic motor neurons. To test this, we dissected the transcriptional mechanisms responsible for the expression of Pitx/UNC-30 and COUP TFII/UNC-55. We found that different isoforms of the Hox cofactor Meis/UNC-62 stabilize and activate the expression of UNC-55. Furthermore, we conclude that Pitx/UNC-30 expression is regulated differently between the two motor neuron sub-classes by Meis/UNC-62, Hox-B7/MAB-5 and NeuroD/CND-1, each of which are vital to the development of different components of the nervous system in vertebrates. Our findings suggest that the GABAergic identity and the sub-class specification of neurons are under the control of multiple conserved transcription factors responsible for neuron fate determination and post mitotic identities.
The impact of hard and soft policy measures on new technology-based firms
Creators: name: Ramaciotti, Laura
name: Muscio, Alessandro
name: Rizzo, Ugo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: Computational Biology

description: The impact of hard and soft policy measures on new technology-based firms. Regional Studies. Entrepreneurship policies in support of new technology-based firms fall into two main categories of intervention: hard measures (financial-type support such as loans and grants) and soft measures (counselling and business advice services). This study investigates the association between hard and soft support measures delivered to entrepreneurs, and the performance of the subsequently constituted new technology-based firms. The empirical framework analyses the outcomes of the Spinner Programme – a regional policy measure implemented in the Italian region of Emilia-Romagna during 2000–06. The analysis finds that soft measures are positively related to a higher probability of exiting the market and to higher sales growth. The results also show that the magnitude of the effect of soft measures on growth is greater than the effect of hard measures.
Regional policies for innovation: the case of technology districts in Italy
Creators: name: Bertamino, Federica
name: Bronzini, Raffaello
name: Maggio, Marco De
name: Revelli, Davide
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Regional policies for innovation: the case of technology districts in Italy. Regional Studies. This paper studies a policy tool implemented in Italy in the last decade to foster local innovation activity called technology districts. First, it examines the characteristics of technology districts and those of the firms within them. Next, it assesses the performance of district firms. The South of Italy has more technology districts, but they are small, poorly sectorially diversified and far from the economic structure of the area. Firms that did join a district had previously been, on average, larger, more innovative and profitable, and show also higher leverage than the others. After the institution of a district the performance of the firms that joined it did not differ significantly from that of similar firms that did not.