cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Parameterized Approximation for Robust Clustering in Discrete Geometric Spaces
Creators: name: Abbasi, Fateme
name: Banerjee, Sandip
name: Byrka, Jarosław
name: Chalermsook, Parinya
name: Gadekar, Ameet
name: Khodamoradi, Kamyar
name: Marx, Dániel
name: Sharma, Roohani
name: Spoerhase, Joachim
Publisher: name: arXiv
Year: 2023
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: Computational Geometry (cs.CG)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: We consider the well-studied Robust $(k, z)$-Clustering problem, which generalizes the classic $k$-Median, $k$-Means, and $k$-Center problems. Given a constant $z\ge 1$, the input to Robust $(k, z)$-Clustering is a set $P$ of $n$ weighted points in a metric space $(M,δ)$ and a positive integer $k$. Further, each point belongs to one (or more) of the $m$ many different groups $S_1,S_2,\ldots,S_m$. Our goal is to find a set $X$ of $k$ centers such that $\max_{i \in [m]} \sum_{p \in S_i} w(p) δ(p,X)^z$ is minimized.
 This problem arises in the domains of robust optimization [Anthony, Goyal, Gupta, Nagarajan, Math. Oper. Res. 2010] and in algorithmic fairness. For polynomial time computation, an approximation factor of $O(\log m/\log\log m)$ is known [Makarychev, Vakilian, COLT $2021$], which is tight under a plausible complexity assumption even in the line metrics. For FPT time, there is a $(3^z+ε)$-approximation algorithm, which is tight under GAP-ETH [Goyal, Jaiswal, Inf. Proc. Letters, 2023].
 Motivated by the tight lower bounds for general discrete metrics, we focus on \emph{geometric} spaces such as the (discrete) high-dimensional Euclidean setting and metrics of low doubling dimension, which play an important role in data analysis applications. First, for a universal constant $η_0 >0.0006$, we devise a $3^z(1-η_{0})$-factor FPT approximation algorithm for discrete high-dimensional Euclidean spaces thereby bypassing the lower bound for general metrics. We complement this result by showing that even the special case of $k$-Center in dimension $Θ(\log n)$ is $(\sqrt{3/2}- o(1))$-hard to approximate for FPT algorithms. Finally, we complete the FPT approximation landscape by designing an FPT $(1+ε)$-approximation scheme (EPAS) for the metric of sub-logarithmic doubling dimension.
description: 26 pages, 5 figures
title: Die Erstsprache als Unterstützung für den Zweitspracherwerb?
Creators: name: Linder, Angela
Year: 2021

description: Vorliegende Masterarbeit beschäftigt sich mit der Rolle, die Mehrsprachigkeit innerhalb des Zweitspracherwerbs bei Erwachsenen einnimmt. In der theoretischen Auseinandersetzung wird dabei neben Fragen, die sich mit den Auswirkungen des Einbezugs der Erstsprache auf den Zweitspracherwerb beschäftigen, der Blick auch auf den Umgang mit Mehrsprachigkeit innerhalb der Bildungsinstitutionen Österreichs gerichtet sowie Ansätze präsentiert, die das Potential der Mehrsprachigkeit sichtbar machen. Im Sinne einer kontrastiven Linguistik werden außerdem die Sprachen Deutsch und Arabisch einander gegenübergestellt. Die der Arbeit zugrunde liegende empirische Untersuchung geht der Frage nach, ob und auf welche Weise der Einsatz schriftlicher Informationen zu Relativsätzen auf Arabisch eine Unterstützung beim Erlernen der Relativsätze auf Deutsch sein kann. Um diese Frage beantworten zu können, wurde eine Vorgehensweise gewählt, die im Sinne der Triangulation verschiedene Untersuchungsmethoden, wie Sprachstandsfeststellung, Unterrichtsversuch und Gruppendiskussion, miteinander vereint. Die Ergebnisse der Untersuchung machten deutlich, dass ein Einbezug von schriftlichen Informationen in der Erstsprache sich aus Sicht der Lernenden positiv auf den Deutscherwerb auswirken kann, wobei die Testergebnisse dies nur zum Teil bestätigen konnten.
Оптимизация доз применения удобрений на серых лесных почвах Верхневолжья
Creators: name: Окорков В.В.
Publisher: name: Владимирский земледелец
Year: 2018
Subjects: 7-ПОЛЬНЫЙ ЗЕРНОТРАВЯНОЙ СЕВООБОРОТ
СЕРАЯ ЛЕСНАЯ ПОЧВА
ВЫНОС ЭЛЕМЕНТОВ ПИТАНИЯ ЗА СЕВООБОРОТ
МОБИЛИЗАЦИОННЫЙ ПУЛ АЗОТА
МОБИЛЬНЫЙ ФОНД АЗОТА
БАЛАНС ЭЛЕМЕНТОВ ПИТАНИЯ

description: Приведены наиболее применяемые сегодня методы расчета доз удобрений под возделываемые культуры. Для более корректного их использования предлагается оценивать вынос элементов питания основной продукцией за ротацию севооборота, опираясь на запасы нитратного и аммонийного азота в жидкой фазе почвы (мобильный фонд азота) в ранний период вегетации культур. Для его определения использовали тесную линейную взаимосвязь мобилизационного пула азота с его мобильным фондом. Среднегодовую продуктивность севооборота рассчитывали, используя гиперболическую зависимость последней от мобильного фонда азота. Предлагаемые дозы удобрений оценивали по их окупаемости и балансу в почве элементов питания. Минеральные системы удобрения наиболее окупаемы (6,8-7,0 кг зерн.ед./кг д.в.), но они не обеспечивают положительного баланса азота и калия. Для поддержания плодородия серых лесных почв Верхневолжья и обеспечения окупаемости 1 кг д.в. удобрений на уровне 5,3-5,4 кг зерн.ед. (без учета д.в. навоза 8,3-8,8 кг зерн.ед.) наиболее эффективны органоминеральные системы удобрения, которые предусматривают сочетание среднегодовой дозы N40-45P40-45K40-45 с внесением 40-60 т/га навоза КРС за ротацию 7-польного зернотравяного севооборота.
Plasmazellen als therapeutisches Target bei systemischem Lupus erythematodes
Creators: name: Alexander, Tobias
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: plasma cells
subject: lupus
subject: depletion
subject: Daratumumab
subject: Bortezomib
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Obwohl Plasmazellen Autoantikörper sezernieren, standen sie als therapeutisches Target bei Autoimmunerkrankungen lange im Schatten ihrer Vorläuferzellen, den B-Zellen. Erst mit der Erkenntnis, dass ein Kompartiment von langlebigen Plasmazellen durch kontinuierliche Autoantikörpersekretion an der Entwicklung und Aufrechterhaltung von chronischen Autoimmunprozessen beteiligt und durch immunsuppressive und B-Zell-gerichtete Behandlungen nicht zu eliminieren ist, rückten sie in den Fokus zielgerichteter Therapieansätze. Basierend auf erfolgreichen Ergebnissen in Mausmodellen haben wir in translationalen Forschungsansätzen innovative Plasmazell-gerichtete Therapien mit dem Proteasom-Inhibitor Bortezomib und dem monoklonalen Anti-CD38-Antikörper Daratumumab bei SLE-Patienten mit schweren und teilweise lebensbedrohlichen Krankheitsverläufen angewendet. Dabei konnte jeweils eine signifikante Reduktion von Autoantikörpern um 50-60% erzielt werden, die mit einer relevanten Verbesserung der Krankheitsaktivität der Patienten verbunden war. Diese Daten demonstrieren eindrücklich die therapeutische Relevanz einer Plasmazelldepletion beim SLE. Im Verlauf könnten weitere Zielstrukturen auf Plasmazellen für Therapieansätze ausgenutzt werden, z.B. BCMA oder SLAM-F7, wofür bereits therapeutische Antikörper aus der Krebstherapie zur Verfügung stehen. Insgesamt sind diese Ergebnisse auf andere systemische Autoantikörper-vermittelte Erkrankungen übertragbar und bieten Hoffnung auf künftig wirksamere Therapieansätze. Alle verfügbaren Plasmazell-gerichteten Therapien haben den Nachteil, dass auch die humorale Immunität beeinträchtigt wird. Deshalb arbeiten wir an der Vision, sehr selektiv nur jene Plasmazellen, die pathogene Autoantikörper produzieren, zu eliminieren, ohne dabei die humorale Immunität zu schädigen. In Tierversuchen konnten wir bereits demonstrieren, dass diese Vision mit Hilfe einer Affinitätsmatrix-Technologie Wirklichkeit werden kann. Alternativ könnte zukünftig eine Plasmazelldepletion mit Hilfe der CAR-T-Zell-Technologie erfolgen, die zur Therapie des Multiplen Myeloms entwickelt und wirksam eingesetzt wird. Hier steht mit der BCMA-CAR-T-Zell-Therapie bereits eine erfolgversprechende Behandlungsmöglichkeit zur Verfügung.
Additional file 3 of Integrative in silico and in vitro transcriptomics analysis revealed new lncRNAs related to intrinsic apoptotic genes in colorectal cancer
Creators: name: Akbari, Fatemeh
name: Peymani, Maryam
name: Salehzadeh, Ali
name: Ghaedi, Kamran
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. List of 48 genes in related to the apoptosis pathway.
Federated Composite Saddle Point Optimization
Creators: name: Bai, Site
name: Bullins, Brian
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: Optimization and Control (math.OC)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Federated learning (FL) approaches for saddle point problems (SPP) have recently gained in popularity due to the critical role they play in machine learning (ML). Existing works mostly target smooth unconstrained objectives in Euclidean space, whereas ML problems often involve constraints or non-smooth regularization, which results in a need for composite optimization. Addressing these issues, we propose Federated Dual Extrapolation (FeDualEx), an extra-step primal-dual algorithm, which is the first of its kind that encompasses both saddle point optimization and composite objectives under the FL paradigm. Both the convergence analysis and the empirical evaluation demonstrate the effectiveness of FeDualEx in these challenging settings. In addition, even for the sequential version of FeDualEx, we provide rates for the stochastic composite saddle point setting which, to our knowledge, are not found in prior literature.
Erosion of synchronization in networks of coupled oscillators
Creators: name: Skardal, Per Sebastian
name: Taylor, Dane
name: Sun, Jie
name: Arenas, Alex
Publisher: name: arXiv
Year: 2014
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Dynamical Systems (math.DS)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We report erosion of synchronization in networks of coupled phase oscillators, a phenomenon where perfect phase synchronization is unattainable in steady-state, even in the limit of infinite coupling. An analysis reveals that the total erosion is separable into the product of terms characterizing coupling frustration and structural heterogeneity, both of which amplify erosion. The latter, however, can differ significantly from degree heterogeneity. Finally, we show that erosion is marked by the reorganization of oscillators according to their node degrees rather than their natural frequencies.
description: 5 pages, 4 figures
Data Management Package for the novel data delivery system, ServiceX, and its application to an ATLAS Run-2 Physics Analysis Workflow
Creators: name: Kyungeon Choi
Publisher: name: Zenodo
Year: 2022

description: Recent developments of HEP software in the Python ecosystem allow novel approaches to physics analysis workflows. The novel data delivery system, ServiceX, can be very effective when accessing large datasets at remote grid sites. ServiceX can deliver user-selected columns with filtering and run at scale. I will introduce the ServiceX data management package, ServiceX DataBinder, for easy manipulations of ServiceX delivery requests and delivered data using a single configuration file. I will also introduce the effort to integrate ServiceX and Coffea into an ongoing ATLAS Run-2 physics analysis.
Novel Differential Conductance Oscillations in Asymmetric Quantum Point Contacts
Creators: name: Zhang, Hao
name: Wu, Phillip M.
name: Chang, Albert M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Small differential conductance oscillations as a function of source-drain bias were observed and systematically studied in an asymmetric quantum point contact (QPC). These oscillations become significantly suppressed in a small in-plane magnetic field ($\sim~0.7~T$) or at higher temperatures ($\sim~800~mK$). Qualitatively, their temperature evolution can be simulated numerically based on smearing of the Fermi distribution, whereas features near zero-bias cannot. Single particle scenarios are unsatisfactory in accounting for the oscillations, suggesting that they are likely caused by electron and spin correlation effects.
description: 5 figures
title: Kino & Keller
Creators: name: Holzmüller, Marian
Year: 2021

description: Der klaustrophobische filmische Raum ist bemerkenswert. Durch seine besondere Form, die aufgrund der Reduktion filmischer Mittel entsteht, etablieren sich vielschich-tige Bedeutungsebenen, welche sich besonders deutlich im Kontext des filmischen Kellers beleuchten lassen. Die Arbeit beantwortet dahingehend nicht nur die Frage, wie Enge im Film entsteht, sondern auch, welche Bedeutung sie insbesondere im Zu-sammenhang mit unterirdischen klaustrophobischen Räumen für den Film hat. Die vorgenommene Typologisierung des Kellers im Film zeigt seine vielfältige Funktionali-tät auf und bietet eine analytische Hilfestellung in seiner Interpretation und wissen-schaftlichen Auseinandersetzung. Die jeweiligen Kellertypen transportieren dabei un-terschiedliche Bedeutungsebenen, die je nach Gestalt und dramaturgischer wie narra-tiver Einbettung des Kellerraumes variieren können, bzw. miteinander korrelieren. So zeigen sich in der Analyse verschiedener Filmkeller unterschiedliche Funktionen des unterirdischen Filmraumes, die Aufschluss über film-, wie raumtheoretische Fragestel-lungen geben können.
description: The claustrophobic cinematic space is remarkable. Through its special form, which arises due to the reduction of cinematic resources, complex levels of significance are established, which can be illuminated particularly clearly in the context of the cinemat-ic cellar. In this respect, the study not only answers the question of how narrowness arises in film, but also which meaning it has for the film, especially in the context of subterranean claustrophobic spaces. The typology of the cellar in the film shows its diverse functionality and offers an analytical assistance in its interpretation and scien-tific discussion. The various types of basements convey different layers of meaning, which can vary depending on the form and dramaturgical as well as narrative embed-ding of the basement space, or correlate with each other. Thus, the analysis of differ-ent film cellars reveals different functions of the subterranean film space, which can provide information about film- and space-theoretical questions.
Supplementary material from Captive and urban environments are associated with distinct gut microbiota in deer mice (Peromyscus maniculatus)
Creators: name: Diaz, Jessica
name: Redford, Kent H.
name: Reese, Aspen T.
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Supplementary methods and supplementary figures 1-4.
Mechanically actuated Kerr soliton microcombs
Creators: name: Fujii, Shun
name: Wada, Koshiro
name: Kogure, Soma
name: Tanabe, Takasumi
Publisher: name: arXiv
Year: 2023
Subjects: subject: Optics (physics.optics)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Mode-locked ultrashort pulse sources with a repetition rate of up to several tens of gigahertz greatly facilitate versatile photonic applications such as frequency synthesis, metrology, radar, and optical communications. Dissipative Kerr soliton microcombs provide an attractive solution as a broadband, high-repetition-rate compact laser system in this context. However, its operation usually requires sophisticated pump laser control to initiate and stabilize the soliton microcombs, particularly in millimeter-sized ultrahigh-Q whispering-gallery resonators. Here, we realize a mechanically actuated soliton microcomb oscillator with a microwave repetition rate of 15 GHz. This enables direct soliton initiation, long-term stabilization, and fine tuning, where the operation now lifts the prerequisite pump laser tunability that must be relaxed if the technology is to be widely used outside the laboratory environment. We reveal the prospects for using this method with a wide range of applications that would benefit from mechanical soliton actuation such as optical clocks, spectral extension, and dual-comb spectroscopy.
On the current status of Modified Gravity
Creators: name: Boubekeur, Lotfi
name: Giusarma, Elena
name: Mena, Olga
name: Ramirez, Hector
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We revisit the cosmological viability of the Hu $\&$ Sawicki modified gravity scenario. The impact of such a modification on the different cosmological observables, including gravitational waves, is carefully described. The most recent cosmological data, as well as constraints on the relationship between the clustering parameter $σ_8$ and the current matter mass-energy density $Ω_m$ from cluster number counts and weak lensing tomography, are considered in our numerical calculations. The strongest bound we find is $|f_{R0}| < 3.7 \times 10^{-6}$ at $95\%$~CL. Forthcoming cluster surveys covering 10,000 deg$^2$ in the sky, with galaxy surface densities of $\mathcal{O}(10)$~arcmin$^{-2}$ could improve the precision in the $σ_8$-$Ω_m$ relationship, tightening the above constraint.
description: 11 pages, 6 figures and 2 Tables. Final published version in the PRD journal
Микробиологические аспекты адаптивно-ландшафтного земледелия в зоне Владимирского ополья
Creators: name: Зинченко М.К.
name: Шаркевич В.В.
name: Федулова И.Д.
Publisher: name: Владимирский земледелец
Year: 2018
Subjects: МИКРОБНАЯ БИОМАССА
СЕРАЯ ЛЕСНАЯ ПОЧВА
ТРАНСФОРМАЦИЯ
ФОНЫ ИНТЕНСИФИКАЦИИ
АГРОЛАНДШАФТЫ
ЧИСЛЕННОСТЬ МИКРООРГАНИЗМОВ
ВЛАДИМИРСКОЕ ОПОЛЬЕ

description: Представлены результаты многолетнего (2006-2017 гг.) мониторинга микробиологических показателей, позволяющих охарактеризовать общую картину состояния почвенной микрофлоры в агроландшафтах серой лесной почвы Владимирского ополья. Исследовали слой почвы 0-20 см в стационарном опыте на минеральных и органоминеральных фонах интенсификации применения удобрений по отвальной вспашке (20-22 см) и безотвальному рыхлению (10-12 см). Значительная часть микробной биомассы в почве агрофонов минерализуется, что может привести к постепенной деградации и снижению ее плодородия. Средний уровень биомассы микроорганизмов в почве пашни составляет 3,2 т/га, что в 3 раза ниже, чем в целинных биотопах. На высокоинтенсивном минеральном фоне (ежегодно 350-390 кг д.в. на 1 га) биомасса микроорганизмов по отвальной вспашке составила 1,9 т/га. На органоминеральных фонах величина этого показателя находилась на уровне 3-3,5 т/га. Антропогенная сукцессия микробного пула эколого-трофических групп интегрирована на увеличение их численности на органоминеральных фонах, где навоз вносили 1 раз за ротацию 6-польных севооборотов в дозе 40, 60 и 80 т/га в сочетании с минеральными удобрениями. Расчет коэффициентов минерализации азота органических соединений (Кмин) и коэффициента трансформации органического вещества (Кпт) свидетельствует, что на органоминеральных фонах формируется бактериальный пул с биохимической активностью, которая функционально направлена на микробиологическую трансформацию мортмассы в органическое вещество почвы.
Thermodynamic limits to information harvesting by sensory systems
Creators: name: Bo, Stefano
name: Del Giudice, Marco
name: Celani, Antonio
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: In view of the relation between information and thermodynamics we investigate how much information about an external protocol can be stored in the memory of a stochastic measurement device given an energy budget. We consider a layered device with a memory component storing information about the external environment by monitoring the history of a sensory part coupled to the environment. We derive an integral fluctuation theorem for the entropy production and a measure of the information accumulated in the memory device. Its most immediate consequence is that the amount of information is bounded by the average thermodynamic entropy produced by the process. At equilibrium no entropy is produced and therefore the memory device does not add any information about the environment to the sensory component. Consequently, if the system operates at equilibrium the addition of a memory component is superfluous. Such device can be used to model the sensing process of a cell measuring the external concentration of a chemical compound and encoding the measurement in the amount of phosphorylated cytoplasmic proteins.
description: Revised version: 18 pages, 5 figures
Report on the status of sensors used for measuring nutrients, biology-related optical properties, variables of the marine carbonate system, and for coastal profiling, within the JERICO network and, more generally, in the European context
Creators: name: Petersen, Wilhelm
name: Möller, Klas
Publisher: name: Jerico-Next
Year: 2017

description: The present deliverable gathers and reports on the outcomes of the four parts of the first JERICO-NEXT workshop on sensors for nutrients, biology-related optical properties, variables of the marine carbonate system, and for coastal profiling. It provides descriptions of such systems and the way they are run, and critically assesses their current level of development from the specific perspective of the operations carried out routinely by the JERICO observing network, and by extension, in the general European context.
description: Ce document regroupe et rend compte des résultats des quatre parties du premier atelier JERICO-NEXT sur les capteurs pour : les nutriments, les propriétés optiques liées à la biologie, les paramètres du système carbonate marin et les systèmes de mesure en profil côtier. Il fournit des descriptions de ces systèmes et la manière dont ils sont gérés, et évalue de manière critique leur niveau actuel de développement à partir de la perspective spécifique des opérations effectuées régulièrement par le réseau d'observation de JERICO et, par extension, dans le contexte européen général.
Продуктивность картофеля в полевом севообороте при использовании различных систем удобрения
Creators: name: Ермакова Л.И.
Publisher: name: Владимирский земледелец
Year: 2018
Subjects: СЕВООБОРОТ
КАРТОФЕЛЬ
СИСТЕМЫ УДОБРЕНИЙ
УРОЖАЙНОСТЬ
СТРУКТУРА УРОЖАЯ
КАЧЕСТВО КЛУБНЕЙ КАРТОФЕЛЯ
ПЛОДОРОДИЕ ПОЧВЫ
ЭКОНОМИЧЕСКАЯ ЭФФЕКТИВНОСТЬ

description: На дерново-подзолистых супесчаных почвах Центрального района Нечерноземной зоны в течение двух ротаций 7 польного зернотравянопропашного севооборота изучали эффективность органоминеральной и биологизированной систем удобрений, рассчитанных на запланированную урожайность картофеля 250 ц/га. При органоминеральной системе удобрения в среднем за 4 года под картофель внесли N257P300K292, при биологизированной с учетом прямого действия соломы, минеральных удобрений и последействия многолетних трав и сидератов N134P51K149. В обоих вариантах получен запланированный урожай с приоритетным содержанием крупной фракции (59 %) с одинаковым выносом элементов питания и содержанием белка и крахмала. При органоминеральной системе удобрения обеспеченность почвы подвижным фосфором увеличилась на 35,7 %, калием на 7,8 %, при биологизированной соответственно на 12,7 % и 4 %. Чистый доход от использования биологизированной системы удобрений был выше, чем при органоминеральной, на 10 тыс./га. Отведение отдаленных поле под биологизированную систему удобрения, сокращает плечо перевозки традиционных органических удобрений, дает возможность экономить значительные средства, технические ресурсы и рабочее время.
Asymptotic expansions relating to the lengths of longest monotone subsequences of involutions
Creators: name: Bornemann, Folkmar
Publisher: name: arXiv
Year: 2023
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 05A16, 60B20, 30D15, 30E15, 33C10

description: We study the distribution of the length of longest monotone subsequences in random (fixed-point free) involutions of $n$ integers as $n$ grows large, establishing asymptotic expansions in powers of $n^{-1/6}$ in the general case and in powers of $n^{-1/3}$ in the fixed-point free cases. Whilst the limit laws were shown by Baik and Rains to be one of the Tracy-Widom distributions $F_β$ for $β=1$ or $β=4$, we find explicit analytic expressions of the first few expansion terms as linear combinations of higher order derivatives of $F_β$ with rational polynomial coefficients. Our derivation is based on a concept of generalized analytic de-Poissonization and is subject to the validity of certain hypotheses for which we provide compelling (computational) evidence. In a preparatory step expansions of the hard-to-soft edge transition laws of L$β$E are studied, which are lifted into expansions of the generalized Poissonized length distributions for large intensities. (This paper continues our work arXiv:2301.02022, which established similar results in the case of general permutations and $β=2$.)
description: V6: updated discussion of the hard-to-soft edge limit with a thinning parameter; Julia code for large scale Monte-Carlo simulations included; 50 pages, 5 figures, 3 tables
EOS -- A software for Flavor Physics Phenomenology
Creators: name: Van Dyk, Danny
Publisher: name: Zenodo
Year: 2022

description: EOS is an open-source software for a variety of computational tasks in flavor physics. Its use cases include theory predictions within and beyond the Standard Model of particle physics, Bayesian inference of theory parameters from experimental and theoretical likelihoods, and simulation of pseudo events for a number of signal processes. EOS ensures high-performance computations through a C++ back-end and ease of usability through a Python front-end. To achieve this flexibility, EOS enables the user to select from a variety of implementations of the relevant decay processes and hadronic matrix elements at run time. We describe the general structure of the software framework and provide basic examples. Further details and in-depth interactive examples are provided as part of the EOS online documentation.
Predictors of treatment response in chronic spontaneous urticaria
Creators: name: Fok, Jie Shen
name: Kolkhir, Pavel
name: Church, Martin K.
name: Maurer, Marcus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: antihistamines
subject: biomarker
subject: chronic spontaneous urticaria
subject: cyclosporine
subject: omalizumab
subject: predictors
subject: treatment
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The current therapeutic algorithm for chronic spontaneous urticaria (CSU), endorsed by the international guideline, entails treatment escalation from second-generation H-1-antihistamines (sgAHs) to omalizumab and cyclosporine until complete response is achieved. Recently, several predictors of response to these treatment options have been described. Here, we discuss the most promising predictors of response and nonresponse to these treatments in CSU. A systematic search was performed by two independent researchers using the MEDLINE/PubMed database with specific keywords and 73 studies included in the review. Levels of evidence were categorized as strong (robust predictors), weak (emerging predictors) or no association, based on the outcome and number of studies available. High disease activity, high levels of C-reactive protein and D-dimer are robust predictors for a poor or no response to sgAHs. Poor or no response to omalizumab is robustly predicted by low serum levels of total IgE. A good response to cyclosporine is robustly predicted by a positive basophil histamine release assay, whereas low total IgE is an emerging predictor. The response to treatment with sgAHs, omalizumab and cyclosporine can be predicted by the use of markers that are readily available in routine clinical practice. Further studies are needed to confirm these predictors.
On 2D discrete Schrödinger operators associated with multiple orthogonal polynomials
Creators: name: Aptekarev, Alexander I
name: Derevyagin, Maxim
name: Van Assche, Walter
Publisher: name: arXiv
Year: 2014
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 39A70, 42C05, 47B36, 47B37, 47B39, 83C20

description: A class of cross-shaped difference operators on a two dimensional lattice is introduced. The main feature of the operators in this class is that their formal eigenvectors consist of multiple orthogonal polynomials. In other words, this scheme generalizes the classical connection between Jacobi matrices and orthogonal polynomials to the case of operators on lattices. Furthermore we also show how to obtain 2D discrete Schrödinger operators out of this construction and give a number of explicit examples based on known families of multiple orthogonal polynomials.
description: 15 pages
Оптимизация кормовых севооборотов с кукурузой
Creators: name: Фролова Л.Д.
Publisher: name: Владимирский земледелец
Year: 2018
Subjects: КУКУРУЗА
ЛЮПИН
БИОЛОГИЧЕСКИЙ АЗОТ
СЕВООБОРОТ ПРЕДШЕСТВЕННИКИ
ДОЗЫ МИНЕРАЛЬНЫХ УДОБРЕНИЙ
ДЕРНОВО-ПОДЗОЛИСТАЯ ПОЧВА
УРОЖАЙНОСТЬ
КАЧЕСТВО КОРМОВ

description: Для снижения затрат при выращивании кукурузы и получения высококачественных кормов на дерново-подзолистых супесчаных почвах были проведены исследования по использованию биологического азота однолетнего люпина (сорт Дега), обладающего высоким симбиотическим эффектом, при питании растений кукурузы (сорт Катерина). Агроприем изучали в двухпольном севообороте: люпин однолетний на силос кукуруза на силос. В качестве варианта сравнения использовали монокультуру кукурузы. Минеральные удобрения под кукурузу вносили в дозах 0; (NPK)30; (NPK)60; (NPK)90; (NPK)120. По сравнению с монокультурой кукурузы, люпин стабилизировал и даже снижал кислотность почвы, улучшал её пищевой режим и биологическую активность, что способствовало повышению урожайности зеленой массы и сухого вещества кукурузы. Одновременно возрастала эффективность минеральных удобрений, что способствовало снижению их оптимальной дозы с (NPK)120 до (NPK)60, создавая экономию только на минеральных удобрениях около 6 тыс. руб./га. Выход кормовых единиц с урожаем кукурузы по люпину возрос на 12 %, накопление сырого протеина на 14, обеспеченность протеином 1 корм. ед. на 12 %. Под влиянием минеральных удобрений в посевах монокультуры кукурузы выход кормовых единиц увеличился на 100 %, белка на 148 %, обеспеченность протеином 1 корм. ед. на 19 %, в варианте с кукурузой по люпиновому предшественнику соответственно на 83, 158, 39 %. То есть биологический азот люпина усиливал функции минеральных удобрений, положительно влияющие на кормовые качества зеленой массы кукурузы. Использование биологического азота люпина значительно снижает экологическую нагрузку от минеральных удобрений на агроландшафты.
Atlantos. Current EOV Report
Creators: name: Etienne, Hélène
name: Rio, Marie-Hélène
Publisher: name: CLS
Year: 2018

description: The objective of this subtask is to demonstrate the value of the in-situ surface currents observing system by ensuring the link with the ESA GlobCurrent project. GlobCurrent is an ESA Data User Element started in October 2013 (running until June 2017) whose objective is “to advance the quantitative estimation of ocean surface currents from satellite sensor synergy and demonstrate impact in user-led scientific, operational and commercial applications that, in turn, will increase the uptake of satellite measurements”. In the framework of Globcurrent, several surface and near-surface current products have been calculated: global, ¼ ° maps of ocean surface geostrophic currents (from altimetry), Ekman currents at two distinct depths (surface and 15m) and combined Geostrophic+Ekman currents at 0 and 15m depth have been calculated for the period January 1993 - May 2016 In this document, we will calculate merged SSH/SST velocity maps over the AtlantOS region for a period with a satisfying drifting buoy coverage and compare them to the AtlantOS drifting buoy velocities. The merged SSH/SST currents could finally be combined to the AtlantOS drifter velocities through a multivariate analysis approach to further improve the ocean surface current retrieval. This method is currently developed in the framework of the CNES DUACS-MR project. In a second chapter, we explore the SISMER SADCP (Shipboard Acoustic Doppler Current Profiler, IFREMER /IDM/SISMER) database to assess the possibility to extract a wind driven component from the measured velocity to compare with an Ekman model and the use of these in-situ data for model validation.
Reconstruction of Quantum Particle Statistics: Bosons, Fermions, and Transtatistics
Creators: name: Sánchez, Nicolás Medina
name: Dakić, Borivoje
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Identical quantum particles exhibit only two types of statistics: bosonic and fermionic. Theoretically, this restriction is commonly established through the symmetrization postulate or (anti)commutation constraints imposed on the algebra of creation and annihilation operators. The physical motivation for these axioms remains poorly understood, leading to various generalizations by modifying the mathematical formalism in somewhat arbitrary ways. In this work, we take an opposing route and classify quantum particle statistics based on operationally well-motivated assumptions. Specifically, we consider that a) the standard (complex) unitary dynamics defines the set of single-particle transformations, and b) phase transformations act locally in the space of multi-particle systems. We develop a complete characterization, which includes bosons and fermions as basic statistics with minimal symmetry. Interestingly, we have discovered whole families of novel statistics (dubbed transtatistics) accompanied by hidden symmetries, generic degeneracy of ground states, and spontaneous symmetry breaking -- effects that are (typically) absent in ordinary statistics.
description: The main theorem extended to negative occupation numbers and exceptional statistics found, the paper accepted for publication in Quantum
Noncrossing Partition Lattices from Planar Configurations
Creators: name: Cohen, Stella
name: Dougherty, Michael
name: Harsh, Andrew D.
name: Martin, Spencer Park
Publisher: name: arXiv
Year: 2023
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05A18, 52A10, 52C35

description: The lattice of noncrossing partitions is well-known for its wide variety of combinatorial appearances and properties. For example, the lattice is rank-symmetric and enumerated by the Catalan numbers. In this article, we introduce a large family of new noncrossing partition lattices with both of these properties, each parametrized by a configuration of n points in the plane.
description: 30 pages, 21 figures. Expanded exposition and fixed errors in Propositions 2.3 and 4.4. Final version
Коллекция овса - источник ценных признаков для решения проблем селекции
Creators: name: Иванова Г.Н.
Publisher: name: Владимирский земледелец
Year: 2018
Subjects: ОВЕС
КОЛЛЕКЦИЯ
УРОЖАЙНОСТЬ
БЕЛОК
ЭЛЕМЕНТЫ ПРОДУКТИВНОСТИ
СЕВЕРНЫЙ КАЗАХСТАН

description: В контрастных погодных условиях Северного Казахстана в 2012-2016 гг. оценивали 165 коллекционных сортообразцов ярового овса по комплексу следующих признаков: продолжительность вегетационного периода, урожайность, содержание белка, количество зерен и масса зерна главной метелки, масса 1000 зерен. Выделены перспективные образцы, которые могут быть исходным материалом для селекции овса на скороспелость (из России К-14664, Покровский, Покровский 9, Новосибирский 88, Хангаласский, Нидерландов К-12362, из Боливии к-13516 Местный, из Беларуси Белорусский голозерный, из США Clintland 60, из Германии Flamingsspize и др.). Ценным исходным материалом служат сортообразцы, стабильно формирующие урожайность (Аргамак, Краснообский, Корифей, Пегас, Тарский 2, Фобос, Льговский 82, Иртыш 22 Россия, Bonus Германия, Ariban Нидерланды, Зирковий Украина, К-13250 Швеция, К-14850 Австралия). Источниками крупнозерности могут стать образцы Иртыш 22, Новосибирский 88, Пегас, Волай (Россия), К-14850 (Австралия). Высоким содержанием белка характеризовались голозерные формы Белорусский голозерный (18,53-21,66 %), Вандроунiк (16,32-19,31 %), К-15090 (18,08-21,2 %), К-15089 (17,59-19,46 %), пленчатые формы Clintland 60 (17,9-18,68 %), К-12234 Guelatao (15,54-17,11 %), К-13588 Manoire (14,9-16,33 %), К-12236 Mantaro (14,58-17,74 %), К-14848 Coomallo (15,86-18,36 %), К-5005 (15,38-21,19 %) и др. По комплексу признаков (урожайность, озерненность, масса зерна главной метелки и масса 1000 зерен) выделились образцы Пегас, Льговский 82 (Россия), Qnoll К-14850 (Австралия), которые послужат исходным материалом для создания новых гибридных форм.
Direct assessment of individual skin barrier components by electrical impedance spectroscopy
Creators: name: Mannweiler, Roman
name: Bergmann, Sophia
name: Vidal‐Y‐Sy, Sabine
name: Brandner, Johanna M.
name: Günzel, Dorothee
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: impedance spectroscopy
subject: reconstructed human epidermis
subject: skin barrier
subject: tight junctions
subject: transepithelial electrical resistance
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Expression of the tight junction proteins Cldn1 and 4 is altered in skin diseases such as atopic dermatitis, and Cldn1 deficiency affects skin barrier formation. Impedance spectroscopy (IS) has been proven to allow detection of alterations in the skin barrier but is currently unable to separate effects on viable epidermis (VE) and stratum corneum (SC). Methods: Effects of siRNA-mediated Cldn1 and 4 knockdown in reconstructed human epidermis (RHE) on VE and SC barrier function were investigated with Ussing chamber-based IS. Barrier components were sequentially altered, employing iron oxide nanoparticles and EGTA, to identify their contribution to the impedance spectrum. Resistance changes due to apically applied hyperosmolar electrolyte were used to identify barrier defects non-invasively. Results: IS of RHE yielded two relaxation frequencies, representing the barrier properties of the SC (similar to 1000 Hz) and VE (similar to 100 Hz). As proof of concept, it was shown that the Cldn1 knockdown-induced resistance drop arises from the impairment of both SC and VE, indicated by a shift of both relaxation frequencies. Hyperosmolar electrolyte penetration allowed non-invasive detection of Cldn1 knockdown via time-dependent frequency shifts. The absence of Cldn4 knockdown-induced changes revealed the weaknesses of transepithelial electrical resistance analysis. Conclusion: In conclusion, the present technique allows to separately measure the barrier properties of SC and VE and further evaluate the Cldn1 and 4 knockdown impact on the skin barrier. As the measurement with agarose-embedded electrolyte allowed non-invasive identification of the Cldn1 knockdown, this opens the way to detailed in vivo skin barrier assessment.
Low-scaling GW algorithm applied to twisted transition-metal dichalcogenide heterobilayers
Creators: name: Graml, Maximilian
name: Zollner, Klaus
name: Hernangómez-Pérez, Daniel
name: Junior, Paulo E. Faria
name: Wilhelm, Jan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: The $GW$ method is widely used for calculating the electronic band structure of materials. The high computational cost of $GW$ algorithms prohibits their application to many systems of interest. We present a periodic, low-scaling and highly efficient $GW$ algorithm that benefits from the locality of the Gaussian basis and the polarizability. The algorithm enables $G_0W_0$ calculations on a MoSe$_2$/WS$_2$ bilayer with 984 atoms per unit cell, in 42 hours using 1536 cores. This is four orders of magnitude faster than a plane-wave $G_0W_0$ algorithm, allowing for unprecedented computational studies of electronic excitations at the nanoscale.
Détection des risques de contamination des Coquilles Saint Jacques en Baie de Seine - DISCCO - Rapport Final
Creators: name: Schapira, Mathilde
name: Courtay, Gaelle
name: Francoise, Sylvaine
Publisher: name: Ifremer
Year: 2017

description: Au cours des trois années d’étude (2013-2015), les concentrations en acide domoïque particulaire (ADp) sont restées inférieures à 60 ng l-1 sur l’ensemble de la zone et aucun dépassement de seuil n’a été observé dans les coquillages au cours de cette même période. Lors de la crise sanitaire de 2012, des concentrations en ADp de plus de 4000 ng l-1 avaient été mesurées au printemps au cours du bloom de Pseudo-nitzschia et des concentrations en AD très élevées avaient rapidement été observées dans les coquilles Saint Jacques dès le début de l’été. Ces observations suggèrent que des concentrations en ADp inférieures à 100 ng l-1 seraient insuffisantes pour une contamination massive des bivalves filtreurs en baie de Seine. Ces résultats sont en accord avec une étude récente qui détermine un risque de toxicité potentielle des coquillages pour des concentrations en ADp > 1000 ng l-1 (McKibben et al., 2015). Par ailleurs, les concentrations en acide domoïque dissout (ADd) mesurées en baie de Seine en 2015 (valeur max=75 ng l-1), plus élevées que celles relevées simultanément dans la phase particulaire soulèvent de nombreuses questions. Ces résultats mettent en évidence la nécessité d’approfondir nos connaissances sur le transfert de l’AD entre les différentes phases (i.e. particulaire et dissout) et entre les différents compartiments (i.e. colonne d’eau, organismes marins et sédiment) afin de mieux appréhender les conséquences de ces efflorescences toxiques sur le fonctionnement et la résilience des écosystèmes côtiers.
Charakterisierung sprachlicher Veränderungen bei Bewegungsstörungen
Creators: name: Tiedt, Hannes Ole
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Deep Brain Stimulation
subject: Parkinson's Disease
subject: Essential Tremor
subject: Language
subject: Verbal Fluency
subject: Event-Related Potentials
subject: N400
subject: Thalamus
subject: Basal Ganglia
subject: Subthalamic Nucleus
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Die hier dargestellten Arbeiten charakterisieren sprachliche Funktionen subkortikaler Strukturen im Kontext von Bewegungsstörungen (Essentieller Tremor und Parkinson-Erkrankung) und die kognitiv-sprachlichen Effekte der eingesetzten Therapieverfahren der Tiefen Hirnstimulation (Deep Brain Stimulation, DBS) und pharmakologischer (v.a. dopaminerger) Therapie. Eingesetzt wurden elektrophysiologische und behaviorale Analysen unter Verwendung linguistischer Methoden zur Untersuchung der Produktion und Verarbeitung von Sprache. Bei Patienten und Patientinnen mit Parkinson kommt es durch Medikation und subthalamischer DBS häufig zu einer subtilen Verbesserung von sprachlichen Leistungen durch die positive Beeinflussung exekutiver Prozesse. Dopaminerge Medikation führt außerdem zu einer Modulation der automatischen Aktivierung semantischer Netzwerke, die möglicherweise nicht mit dem Ausgleich fronto-striataler Dopamindepletion sondern vielmehr dopaminerger Stimulation prä-frontaler Netzwerke zusammenhängt. Thalamische Kerne scheinen im Gegensatz zu basalganglionären Strukturen und dem Nucleus subthalamicus insbesondere spezifischer in lexiko-semantische Prozesse sowohl während der Worterkennung und der Sprachproduktion eingebunden zu sein. Dies ließ sich in den vorgestellten Arbeiten für lexikalische Verarbeitung sowie im Rahmen formaler Sprachtestung mittels Wortflüssigkeitsaufgaben und linguistischer Analysen der Spontansprache zeigen. Die Ergebnisse lassen sich im Kontext einer funktionellen Dichotomie subkortikaler Strukturen für Sprache interpretieren: Basalganglionäre Strukturen und der Nucleus subthalamicus insbesondere lassen sich mit vorwiegend exekutiven bzw. prozeduralen Funktionen wie z.B. morphosyntaktischen Aspekten sprachlicher Prozesse verbinden. Thalamische Kerne erscheinen dagegen durch die Modulation kortiko-thalamo-kortikaler Konnektivität mit sprachspezifischeren lexiko-semantischen Prozessen assoziiert zu sein.
Time dependence of partition into spectators and participants in relativistic heavy-ion collisions
Creators: name: Vovchenko, V.
name: Anchishkin, D.
name: Csernai, L. P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The process of formation of the participant system in heavy-ion collisions is investigated in the framework of a simplified analytic Glauber-like model, which is based on the relativistic Boltzmann transport equation. The key point lies in the time-dependent partition of the nucleon system into two groups: nucleons, which did not take part in any interaction before a given time and nucleons, which already have interacted. In the framework of the proposed model we introduce a natural energy-dependent temporal scale $t_c$, which allows us to remove all dependencies of the model on the collision energy except for the energy dependence of the nucleon-nucleon cross-section. By investigating the time dependence of the total number of participants we conclude that the formation process of the participant system becomes complete at $t\simeq1.5 t_c$. Time dependencies of participant total angular momentum and vorticity are also considered and used to describe the emergence of rotation in the reaction plane.
description: 24 pages, 10 figures, minor changes to match published version
Additional file 1 of Modern treatment outcomes for early T-stage oropharyngeal cancer treated with intensity-modulated radiation therapy at a tertiary care institution
Creators: name: Gravio, Eric J. Di
name: Pencilla Lang
name: Kim, Hugh Andrew Jinwook
name: Chinnery, Tricia
name: Mundi, Neil
name: S. Danielle MacNeil
name: Mendez, Adrian
name: Yoo, John
name: Fung, Kevin
name: Mymryk, Joe S.
name: Barrett, John W.
name: Read, Nancy
name: Varagur Venkatesan
name: Kuruvilla, Sara
name: Mendez, Lucas C.
name: Winquist, Eric
name: Mitchell, Sylvia
name: Mattonen, Sarah A.
name: Nichols, Anthony C.
name: Palma, David A.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Additional file 1. Univariable and multivariable analysis of overall survival in all patients with early stage disease seen at the London Health Sciences Centre from 2014 to 2018 by clinical characteristics. Samples missing clinical information were excluded (30 patients were excluded, 168 remaining samples in the analysis). Backwards step-wise method was utilized to arrive at the final multivariate model that was based on patient age, alcohol abuse, and smoking status. P-values