cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Tick-borne encephalitis virus triggers inositol-requiring enzyme 1 (IRE1) and transcription factor 6 (ATF6) pathways of unfolded protein response
Creators: name: Yu, Chao
name: Achazi, Katharina
name: Niedrig, Matthias
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2013
Subjects: subject: Flavivirus
subject: Tick-borne encephalitis virus
subject: ER stress
subject: XBP1
subject: ATF6
subject: Virus replication
subject: 610 Medizin

description: Tick-borne encephalitis (TBE) is a serious human neurological disease caused by TBE virus (TBEV). However, the mechanisms of TBEV-caused pathogenesis remain unclear. The endoplasmic reticulum (ER) stress response, also defined as the unfolded protein response (UPR), is an important conserved molecular signaling pathway that modulates many biological functions including innate immunity and viral pathogenesis. Here, we investigated the effects of the two UPR signaling pathways upon TBEV infection in Vero E6 cells. We showed that the amount of heat shock protein 72 (Hsp72) increased in the course of TBEV infection. We then confirmed that TBEV infection activates the IRE1 pathway, leading to RNA and protein expression of the spliced X box binding protein 1 (sXBP1). Furthermore, we observed the translocation of ATF6 during TBEV infection and expression of cleaved transcription factor 6 (ATF6) which suggest activation of ATF6 pathway. Finally, we examined whether inhibition of the IRE1 pathway has an effect on TBEV infection. Cell treatment with 3,5-Dibromosalicylaldehyde (IRE1 inhibitor) and tauroursodeoxycholic acid (TUDCA) showed that TBEV replication was significantly limited. These findings provide the first evidence that TBEV infection activates the two UPR signaling pathways. Moreover, inhibition of TBEV replication by UPR inhibitors may provide a novel therapeutic strategy against TBE.
Additional file 1 of Comparing risk-adjusted inpatient fall rates internationally: validation of a risk-adjustment model using multicentre cross-sectional data from hospitals in Switzerland and Austria
Creators: name: Bernet, Niklaus S.
name: Everink, Irma H. J.
name: Hahn, Sabine
name: Bauer, Silvia
name: Schols, Jos M. G. A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology

description: Supplementary Material 1.
From Pulpit to Parish: Preaching Dance and Parish Dances in England and Scandinavia, 1300-1700
Creators: name: Miller Renberg, Lynneth
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Middle Ages
subject: Dance
subject: Church history
subject: Sex role
subject: Renaissance

description: This article considers English and Scandinavian sermon tales alongside accounts of parish practice from 1300-1700, focusing on dance among the laity. It posits that the negative perspective of Scandinavian Protestants towards dance was a result of the medieval North Sea networks that brought England’s approach to dance to Nordic parishes, shaping the approach to lay dance and parish culture in both regions.  The circulation of medieval English sermon tales like Robert Mannyng of Brunne’s Handlyng Synne in Scandinavian contexts meant that this particularly English view of dance spread in early modern Scandinavian parishes and sermon tales. Sources like Mannyng’s show how, unlike Latinate or French sources, the English vernacular approach aggressively connected dance to female transgression and sacrilege. This sharing of sermon literature between England and Scandinavia helps to explain the emphasis on gendered transgression in northern accounts of dance, with important ramifications for parish discipline and oversight.
Betrachtungen zur Durchseuchung und beobachteter Aktivität bei Influenza B
Creators: name: Uphoff, Helmut
name: Heckler, Rolf
name: Schweiger, Brunhilde
Publisher: name: Robert Koch-Institut
Year: 1998
Subjects: subject: 610 Medizin

description: Anhand der Influenza-Surveillancedaten von 1988/89 bis 1997/98 wurde für Influenza B ein einfaches Modell für das Wechselspiel von Populationsimmunität und Influenzaaktivität entwickelt. Dafür wurde ein Index für die Populationsimmunität aus der Verbreitung der Influenza B in den fünf vorangegangenen Beobachtungsperioden bestimmt. Die Ermittlung der anzunehmenden Abnahme der Bedeutung der Durchseuchung mit der Zeit, aufgrund der Drift und sinkender Antikörpertiter, erfolgte anhand des Modells mit empirischen Methoden. Es konnte eine enge Korrelation zwischen Immunitätsindex und beobachteter Verbreitung der Influenza B innerhalb der sechs aus den Daten berechenbaren Beobachtungsperioden (1992/93 bis 1997/98) hergestellt werden.
Agave on Cawdor Road, a part of local folklore
Creators: name: Willis, Ian
Publisher: name: Camden History Notes
Year: 2024
Subjects: subject: New South Wales
subject: Folklore
subject: New South Wales--Sydney
subject: Settler colonialism
subject: Australia
subject: Plants

description: This blog post tells the story of the agave plants near Cawdor Road, Camden, which have become part of local folklore. Stories span murder, historical colonial gardens, and Indigenous conflict. These slow-growing succulents have sparked controversy and conjecture, with their true history and significance remaining a mystery. Despite attempts to uncover the truth, the agave's legend endures across generations.
Additional file 2 of Comparing risk-adjusted inpatient fall rates internationally: validation of a risk-adjustment model using multicentre cross-sectional data from hospitals in Switzerland and Austria
Creators: name: Bernet, Niklaus S.
name: Everink, Irma H. J.
name: Hahn, Sabine
name: Bauer, Silvia
name: Schols, Jos M. G. A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology

description: Supplementary Material 2.
AI Model Integration & Cross-Domain Collaboration Engine
Creators: name: Krishnakumar Kannan
Publisher: name: Zenodo
Year: 2025

description: The AI Model Integration & Cross-Domain Collaboration Engine is responsible for seamlessly connecting multiple AI models across various domains, ensuring that AI systems can share knowledge, collaborate, and evolve dynamically. This engine allows AI models trained in different fields—such as physics, medicine, finance, and storytelling—to exchange insights, enabling holistic decision-making and innovative discoveries.
Carbon footprint methodology and case studies applied to drinking water, sewage and wastewater treatment sectors
Creators: name: eusebi, anna laura
Publisher: name: Zenodo
Year: 2025
Subjects: Life cycle
Carbon footprint
Wastewater treatment plants
Greenhouse gas emissions

description: This presentation belongs to a presentation that was given during the Winter School on 'Consequences of climate change addressed through SES applied to water and wastewater management for increased resiliency and efficiency, and IT solutions or current/circulation models for coastal management', held on 27-31 January 2025 in Ancona, İtaly for SMART4ENV Project.  The winter school lasted for 5 days and Presentations/studies/lectures were presented on the first 2 days on "Wastewater Field", on the 3rd day on "Coastal protection and resilience under the threat of climate change", on the 4th day on "Water and Wastewater" and on the 5th day on "Coastal".

This presentation at the 4th session of the lectures titled "Wastwater Field", held on the firts day, Prof. Anna Laura Eusebi from UNIVPM shared develop knowledge of the methodology used to assess the carbon footprint of water treatment plants, sewage pipes and wastewater treatment plants with the aim of reducing energy and greenhouse gas emissions and promoting sustainability. Experiences were also be shared with case studies. Additionally, in the presentation, information was given about the life cycle analysis and methodology.
Moments of the Nonnegative Adjusted Estimator of Squared Multiple Correlation
Creators: name: Lucke, Joseph F.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Neuroscience
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: I present the moments of the nonnegative adjusted estimator of the squared multiple correlation ρ2, the coefficient of determination for random-predictor regression. This estimator, first proposed by Ezekiel, replaces with zero the negative estimates from the well-known adjusted estimator proposed by Fisher that, in turn, corrects the positive bias of the sample R2. Although Fisher’s version is presented in texts, Ezekiel’s version is used in practice. Each moment comprises a binomial sum of a negative binomial series of incomplete beta functions. Numerical computations, for which an R function is provided, are required to examine the moments. Ezekiel’s estimator is positively biased for smaller ρ2 and negatively biased for larger. It dominates Fisher’s via MSE. It does not dominate R2, but the MSE of Ezekiel’s estimator can be substantially smaller but at most negligibly larger. Possible applications to powers of ρ2 and to other adjusted estimators are briefly discussed.
Additional file 3 of Comparing risk-adjusted inpatient fall rates internationally: validation of a risk-adjustment model using multicentre cross-sectional data from hospitals in Switzerland and Austria
Creators: name: Bernet, Niklaus S.
name: Everink, Irma H. J.
name: Hahn, Sabine
name: Bauer, Silvia
name: Schols, Jos M. G. A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology

description: Supplementary Material 3.
sj-pdf-1-sgo-10.1177_21582440211027966 – Supplemental material for Environmental Beliefs and Pro-Environmental Behavioral Intention of an Environmentally Themed Exhibition Audience: The Mediation Role of Exhibition Attachment
Creators: name: Li, Xi
name: Yu, Runzhe
name: Su, Xinwei
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Communication and Media Studies not elsewhere classified
subject: Criminology not elsewhere classified
subject: Education
subject: Psychology not elsewhere classified
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-sgo-10.1177_21582440211027966 for Environmental Beliefs and Pro-Environmental Behavioral Intention of an Environmentally Themed Exhibition Audience: The Mediation Role of Exhibition Attachment by Xi Li, Runzhe Yu and Xinwei Su in SAGE Open
sj-pdf-1-aop-10.1177_10600280211028882 – Supplemental material for Low-Dose Tocilizumab With High-Dose Corticosteroids in Patients Hospitalized for COVID-19 Hypoxic Respiratory Failure Improves Mortality Without Increased Infection Risk
Creators: name: Brosnahan, Shari B.
name: Chen, Xian Jie Cindy
name: Chung, Juri
name: Altshuler, Diana
name: Islam, Shahidul
name: Thomas, Sarun V.
name: Winner, Megan D.
name: Greco, Allison A.
name: Divers, Jasmin
name: Spiegler, Peter
name: Sterman, Daniel H.
name: Parnia, Sam
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-aop-10.1177_10600280211028882 for Low-Dose Tocilizumab With High-Dose Corticosteroids in Patients Hospitalized for COVID-19 Hypoxic Respiratory Failure Improves Mortality Without Increased Infection Risk by Shari B. Brosnahan, Xian Jie Cindy Chen, Juri Chung, Diana Altshuler, Shahidul Islam, Sarun V. Thomas, Megan D. Winner, Allison A. Greco, Jasmin Divers, Peter Spiegler, Daniel H. Sterman and Sam Parnia in Annals of Pharmacotherapy
sj-pdf-1-trc-10.1177_19400829211028127 - Supplemental material for Balancing Bees and Livestock: Pastoralist Knowledge, Perceptions and Implications for Pollinator Conservation in Rangelands, Northern Tanzania
Creators: name: Mpondo, Faith Thomas
name: Ndakidemi, Patrick A.
name: Treydte, Anna C.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Geography
subject: 120505 Regional Analysis and Development
subject: FOS: Social and economic geography

description: Supplemental material, sj-pdf-1-trc-10.1177_19400829211028127 for Balancing Bees and Livestock: Pastoralist Knowledge, Perceptions and Implications for Pollinator Conservation in Rangelands, Northern Tanzania by Faith Thomas Mpondo, Patrick A. Ndakidemi and Anna C. Treydte in Tropical Conservation Science
Agave on Cawdor Road, a part of local folklore
Creators: name: Willis, Ian
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Australia
subject: New South Wales
subject: New South Wales--Sydney
subject: Settler colonialism
subject: Folklore
subject: Plants

description: This blog post tells the story of the agave plants near Cawdor Road, Camden, which have become part of local folklore. Stories span murder, historical colonial gardens, and Indigenous conflict. These slow-growing succulents have sparked controversy and conjecture, with their true history and significance remaining a mystery. Despite attempts to uncover the truth, the agave's legend endures across generations.
sj-pdf-3-trc-10.1177_19400829211028127 - Supplemental material for Balancing Bees and Livestock: Pastoralist Knowledge, Perceptions and Implications for Pollinator Conservation in Rangelands, Northern Tanzania
Creators: name: Mpondo, Faith Thomas
name: Ndakidemi, Patrick A.
name: Treydte, Anna C.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Geography
subject: 120505 Regional Analysis and Development
subject: FOS: Social and economic geography

description: Supplemental material, sj-pdf-3-trc-10.1177_19400829211028127 for Balancing Bees and Livestock: Pastoralist Knowledge, Perceptions and Implications for Pollinator Conservation in Rangelands, Northern Tanzania by Faith Thomas Mpondo, Patrick A. Ndakidemi and Anna C. Treydte in Tropical Conservation Science
Physical activity, aerobic fitness and parental socio-economic position among adolescents: the German Health Interview and Examination Survey for Children and Adolescents 2003–2006 (KiGGS)
Creators: name: Finger, Jonas
name: Mensink, Gert
name: Banzer, Winfried
name: Lampert, Thomas
name: Tylleskär, Thorkild
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2014
Subjects: subject: Germany
subject: Adolescents
subject: Physical activity
subject: Socio-economic position
subject: Aerobic fitness
subject: 610 Medizin

description: Background: The positive association between parental socio-economic position (PSEP) and health among adolescents may be partly explained by physical activity behaviour. We investigated the associations between physical activity, aerobic fitness and PSEP in a population based sample of German adolescents. Methods: 5,251 participants, aged 11–17 years, in the German Health Interview and Examination Survey for Children and Adolescents 2003–2006 (KiGGS) underwent a sub-maximal cycle ergometer test and completed a questionnaire obtaining information on physical activity and media use. The associations between physical activity, media use, aerobic fitness and PSEP were analysed with multivariate logistic regression models for boys and girls separately. Odds ratios (ORs) of PSEP (education, occupation and income) on the outcomes were calculated adjusted for age, region, and other influencing factors. Results: Parental education was more strongly associated with the outcome variables than parental occupation and income. After adjusting for age and region, a higher parental education level was associated with better aerobic fitness – with an OR of 1.5 (95% CI 1.2-1.9) for girls whose parents had secondary education and 1.9 (1.4-2.5) for girls whose parents had tertiary education compared to girls whose parents had primary education. The corresponding ORs for boys were 1.3 (1.0-1.6) and 1.6 (1.2-2.1), respectively. Higher parental education level was associated with lower media use: an OR of 2.1 (1.5-3.0) for girls whose parents had secondary education and 2.7 (1.8-4.1) for girls whose parents had primary education compared to girls whose parents had tertiary education. The corresponding ORs for boys were 1.5 (1.2-1.9) and 1.9 (1.5-2.5), respectively. Higher parental education level was associated with a higher physical activity level only among girls: an OR of 1.3 (1.0-1.6) for girls whose parents had secondary education and 1.2 (0.9-1.5) for girls whose parents had tertiary education compared to girls whose parents had primary education. The corresponding ORs for boys were 0.9 (0.8-1.2) and 0.8 (0.6-1.0), respectively. Conclusions: Adolescents of parents with low SEP showed a lower level of aerobic fitness and higher levels of media use than adolescents of parents with higher SEP. Health-promotion interventions need to reach adolescents of parents with low PSEP and stimulate physical activity.
Deuterium fractionation of the starless core L 1498
Creators: name: Lin, Sheng-Jun
name: Lai, Shih-Ping
name: Pagani, Laurent
name: Lefèvre, Charlène
name: Thieme, Travis J.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Molecular deuteration is commonly seen in starless cores and is expected to occur on a timescale comparable to that of the core contraction. Thus, the deuteration serves as a chemical clock, allowing us to investigate dynamical theories of core formation. We aim to provide a 3D cloud description for the starless core L 1498 located in the nearby low-mass star-forming region Taurus, and explore the possible core formation mechanism of L 1498. We carried out non-local thermal equilibrium radiative transfer with multi-transition observations of the high-density tracer N$_2$H$^+$ to derive the density and temperature profiles of the L 1498 core. Combining with the spectral observations of the deuterated species, ortho-H$_2$D$^+$, N$_2$D$^+$, and DCO$^+$, we derived the abundance profiles for observed species and performed chemical modeling of the deuteration profiles across L 1498 to constrain the contraction timescale. We present the first ortho-H$_2$D$^+$ (1$_{10}$-1$_{11}$) detection toward L 1498. We find a peak molecular hydrogen density of $1.6_{-0.3}^{+3.0}\times10^{5}$~cm$^{-3}$, a temperature of 7.5$_{-0.5}^{+0.7}$~K, and a N$_2$H$^+$ deuteration of 0.27$_{-0.15}^{+0.12}$ in the center. We derive a lower limit of the core age for L 1498 of 0.16~Ma which is compatible with the typical free-fall time, indicating that L 1498 likely formed rapidly.
description: 21 pages, 12 figures, accepted for publication in A&A
Neue Broschüre »Krebs in Deutschland« im Dezember 2013 erschienen
Creators: name: Franke, Manuela
name: Wienecke, Antje
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2014
Subjects: subject: 610 Medizin

description: Das Zentrum für Krebsregisterdaten (ZfKD) im Robert Koch-Institut (RKI) hat im Dezember 2013 gemeinsam mit der Gesellschaft der epidemiologischen Krebsregister in Deutschland e.V. (GEKID) die neue Broschüre »Krebs in Deutschland 2009/2010« veröffentlicht. Auf der Webseite des ZfKD steht diese Publikation in deutscher und in Kürze auch in englischer Sprache zum Download zur Verfügung (www.krebsdaten.de).
description: The German Centre for Cancer Registry Data (ZfKD) at the Robert Koch Institute (RKI) and the Association of Population-based Cancer Registries in Germany (Gesellschaft der epidemiologischen Krebsregister in Deutschland (GEKID) have jointly published the new brochure »Cancer in Germany 2009/2010« in December 2013. This brochure is available for download in German and forthcoming also in English on the web page of the ZfKD at www.krebsdaten.de.
sj-docx-1-jpc-10.1177_21501327211027100 – Supplemental material for Prevalence and Factors Associated With Mental Health Symptoms in Adults Undergoing Covid-19 Testing
Creators: name: Osaghae, Ikponmwosa
name: Nguyen, Linh K.
name: Chung, Tong Han
name: Moffitt, Olivia
name: Le, Yen-Chi L.
name: Suh, Mark B.
name: Prasad, Pooja N.
name: Thomas, Eric J.
name: Gordon, Christine D.
name: Hwang, Kevin O.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-docx-1-jpc-10.1177_21501327211027100 for Prevalence and Factors Associated With Mental Health Symptoms in Adults Undergoing Covid-19 Testing by Ikponmwosa Osaghae, Linh K. Nguyen, Tong Han Chung, Olivia Moffitt, Yen-Chi L. Le, Mark B. Suh, Pooja N. Prasad, Eric J. Thomas, Christine D. Gordon and Kevin O. Hwang in Journal of Primary Care & Community Health
ბიბლიოთეკები ანტიკურ ლიტერატურაში
Creators: name: Chichinadze, Giorgi
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 470513
subject: Latin and classical Greek literature
classificationCode: 461006
subject: Library studies

description: The origin of libraries has an ancient history and like so many things, its history begins in ancient Greece and Rome. We find information about libraries not only in official historical and scientific sources, but also in fiction, with such authors as: Aristophanes, Callimachus, Apollonius of Rhodes, Ovid and others. In this article, we will focus on the information provided by them about libraries in fiction.
Molecular Epidemiology and Genotyping of Hepatitis B Virus of HBsAg-Positive Patients in Oman
Creators: name: Baqlani, Said Ali Al
name: Sy, Bui Tien
name: Ratsch, Boris A.
name: Naamani, Khalid Al
name: Awaidy, Salah Al
name: Busaidy, Suleiman Al
name: Pauli, Georg
name: Bock, Thomas
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2014
Subjects: subject: Humans
subject: Female
subject: Male
subject: Amino Acid Sequence
subject: Molecular Sequence Data
subject: Adolescent
subject: Adult
subject: Middle Aged
subject: Young Adult
subject: Genotype
subject: Mutation
subject: Molecular Epidemiology
subject: Reverse Transcriptase Inhibitors/therapeutic use
subject: Drug Resistance Viral/genetics
subject: Hepatitis B Surface Antigens/blood
subject: Hepatitis B Surface Antigens/genetics
subject: Hepatitis B Vaccines/therapeutic use
subject: Hepatitis B virus/genetics
subject: Hepatitis B Chronic/drug therapy
subject: Hepatitis B Chronic/epidemiology
subject: Hepatitis B Chronic/virology
subject: Lamivudine/therapeutic use
subject: Oman/epidemiology
subject: 610 Medizin

description: Background: Hepatitis B virus (HBV) infection is a major global health burden with distinct geographic public health significance. Oman is a country with intermediate HBV carrier prevalence; however, little is known about the incidence of HBV variants in circulation. We investigated the HBV genotype distribution, the occurrence of antiviral resistance, and HBV surface antigen (HBsAg) escape mutations in HBsAg-positive patients in Oman. Methods: Serum samples were collected from 179 chronically HBV-infected patients enrolled in various gastroenterology clinics in Oman. HBV genotypes were determined by sequencing and phylogenetic analysis. Mutations in the HBV polymerase and the HBsAg gene were characterized by mutational analysis. Results: HBV genotypes D (130/170; 76.47%) and A (32/170; 18.28%) are predominant in Oman. The HBV genotypes C and E were less frequent (each 1.18%), while the HBV genotypes B, G, F, and H were not detected. Four patients revealed HBV genotype mixtures (HBV-A/D and D/C). The analyses of vaccine escape mutations yield that 148/170 (87.06%) HBV sequences were wild type. 22/170 (12.94%) HBV sequences showed mutations in the “a” determinant of the HBsAg domain. Two patients showed the described HBV vaccine escape mutation sP120T. 8/146 (5.48%) HBV isolates harbored mutations in the HBV polymerase known to confer resistance against antiviral therapy. Especially the lamivudine resistance mutations rtL180M/rtM204V and rtM204I were detected. Conclusion: This study shows the distribution of HBV genotypes, therapy resistance, and vaccine escape mutations in HBV-infected patients in Oman. Our findings will have a major impact on therapy management and diagnostics of chronic HBV infections in Oman to control HBV infection in this intermediate HBV-endemic country.
Additional file 18 of Iguratimod suppresses Tfh cell differentiation in primary Sjögren’s syndrome patients through inhibiting Akt/mTOR/STAT3 signaling
Creators: name: Lyu, Taibiao
name: Jiang, Hui
name: Zeng, Liuting
name: Liu, Suying
name: He, Chengmei
name: Luo, Chaowen
name: Qiao, Lin
name: Zhao, Yan
name: Chen, Hua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Additional file 18: Supplementary Figure S12. AKT activator restored IGU-suppressed mTOR and STAT3 phosphorylation and T cell proliferation
Responsible AI & Dokumentation
Creators: name: Schulz, Konstantin
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Artificial intelligence
subject: Artificial Intelligence
subject: Natural language processing
subject: Natural Language Processing

description: Diese Präsentation widmet sich der verantwortungsvollen Entwicklung und Dokumentation von KI-Systemen. Sie bietet einen Überblick über zentrale ethische Herausforderungen und deren Bedeutung in der Praxis. Unter Berücksichtigung aktueller Forschungsarbeiten werden Schlüsselthemen wie Werteorientierung bei Datensätzen, Bias-Erkennung sowie die Integration ethischer Normen im Entwicklungsprozess beleuchtet. Ergänzt wird dies durch Ansätze wie das "Red Teaming" von Sprachmodellen, um potenzielle Schwachstellen offenzulegen.

Ein weiterer Fokus liegt auf den Anforderungen an die Dokumentation von KI-Systemen gemäß EU AI Act, einschließlich Aspekten wie Transparenz, menschlicher Aufsicht, Cybersicherheit und Risikoanalyse. Die Präsentation veranschaulicht auch die Initiativen der Humboldt-Universität zu Berlin, darunter Leitlinien zur Nutzung generativer KI in Forschung und Lehre sowie deren Einbettung in eine breite Governance-Strategie.

Abschließend werden praktische Instrumente wie Model Cards und Data Statements vorgestellt, die die strukturierte Dokumentation von KI-Systemen fördern. Diese Ansätze bieten eine Grundlage für ethisch und technisch fundierte KI-Lösungen und unterstützen die Schaffung eines öffentlichen Transparenzstandards, wie er in Städten wie Helsinki und Amsterdam umgesetzt wird.
Improved Testing of Recent HIV-1 Infections with the BioRad Avidity Assay Compared to the Limiting Antigen Avidity Assay and BED Capture Enzyme Immunoassay: Evaluation Using Reference Sample Panels from the German Seroconverter Cohort
Creators: name: Hauser, Andrea
name: Santos-Hövener, Claudia
name: Meixenberger, Karolin
name: Zimmermann, Ruth
name: Somogyi, Sybille
name: Fiedler, Stefan
name: Hofmann, Alexandra
name: Bartmeyer, Barbara
name: Jansen, Klaus
name: Hamouda, Osamah
name: Bannert, Norbert
name: Kücherer, Claudia
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2014
Subjects: subject: Germany
subject: Humans
subject: Cohort Studies
subject: HIV-1/immunology
subject: HIV Seropositivity/immunology
subject: Antibody Affinity/immunology
subject: HIV Antibodies/immunology
subject: HIV Antigens/immunology
subject: HIV Seropositivity/diagnosis
subject: Immunoenzyme Techniques/methods
subject: Immunoenzyme Techniques/standards
subject: Reagent Kits Diagnostic
subject: Reference Standards
subject: 610 Medizin

description: Background: The variety and limitations of current laboratory methods for estimating HIV-incidence has driven attempts to improve and standardize the performance of serological ‘Tests for Recent HIV-Infections’ (TRI). Primary and follow-up HIV-1 positive plasma samples from individuals with well-defined dates of infection collected as part of the German Seroconverter Cohort provided specimens highly suitable for use in comparing the performance of three TRIs: the AWARE™ BED™ EIA HIV-1 Incidence test (BED-CEIA), Genetic systems HIV-1/HIV-2 Plus O EIA antibody avidity-based assay (BioRad Avidity) and Sedia™ HIV-1 LAg Avidity EIA (LAg Avidity). Methods: The evaluation panel included 180 specimens: 44 from antiretroviral (ARV)-naïve individuals with recently acquired HIV-infection (≤130 days; 25 B and 19 non-B subtypes) and 136 from long-term (>12 months) infected individuals [101 ARV-naïve subtype B, 16 non-B subtypes, 14 ARV-treated individuals, 5 slow progressors (SLP)]. Results: For long-term infected, ARV-naïve individuals the false recent rates (FRR) of both the BioRad and LAg Avidity assays were 2% (2/101 for subtype B) and 6% (1/16 for subtype ‘non-B’), while the FRR of the BED-CEIA was 7% (7/101 for subtype B) and 25% (4/16 for subtype ‘non-B’) (all p>0.05). Misclassification of ARV-treated individuals and SLP was rare by LAg (1/14, 0/5) and BioRad Avidity assays (2/14, 1/5) but more frequent by BED-CEIA (5/14, 3/5). Among recently-infected individuals (subtype B), 60% (15/25) were correctly classified by BED-CEIA, 88% (22/25) by BioRad Avidity and significantly fewer by LAg (48%, 12/25) compared to BioRad Avidity (p = 0.005) with a higher true-recency rate among non-B infections for all assays. Conclusions: This study using well-characterized specimens demonstrated lower FRRs for both avidity methods than with the BED-CEIA. For recently infected individuals the BioRad Avidity assay was shown to give the most accurate results.
LSL Linguistics and Literature (D036) Abstracts for the 2025 MLA Convention, New Orleans
Creators: name: Furlong, Anne M.
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Linguistics
subject: FOS: Languages and literature
subject: Language and languages--Style
subject: Translations
subject: Literary style

description: The LSL Forum is hosting two panels (both in person) at the 2025 MLA Convention in New Orleans: Panel I: Visibility, Language, Style: Authorship as Resistance, and Panel II: Translation, visibility, and style: accommodating audiences. I am uploading the abstracts for those planning their visit to the Convention.
On Point Estimators for Gamma and Beta Distributions
Creators: name: Papadatos, Nickos D.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Let X1,…,Xn be a random sample from the gamma distribution with density f(x)=λαxα−1e−λx/Γ(α), x > 0, where both α>0 (the shape parameter) and λ>0 (the reciprocal scale parameter) are unknown. The main result shows that the uniformly minimum variance unbiased estimator (UMVUE) of the shape parameter, α, exists if and only if n≥4; moreover, it has finite variance if and only if n≥6. More precisely, the form of the UMVUE is given for all parametric functions α, λ, 1/α, and 1/λ. Furthermore, a highly efficient estimating procedure for the two-parameter beta distribution is also given. This is based on a Stein-type covariance identity for the beta distribution, followed by an application of the theory of U-statistics and the delta-method.
Online supplementary file 4 - Supplemental material for A Thematic Analysis of Overdose Prevention and Response Efforts in States Experiencing Declines in Rates of Opioid-Involved Overdose Deaths
Creators: name: Robinson, Amber B.
name: Ali, Nida
name: Costa, Olga
name: Rooks-Peck, Cherie
name: Sorensen-Alawad, Amy
name: Ballard, Jonathan
name: Lowerre, Kathryn
name: Fondario, Anna
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, Online supplementary file 4, for A Thematic Analysis of Overdose Prevention and Response Efforts in States Experiencing Declines in Rates of Opioid-Involved Overdose Deaths by Amber B. Robinson, Nida Ali, Olga Costa, Cherie Rooks-Peck, Amy Sorensen-Alawad, Jonathan Ballard, Kathryn Lowerre and Anna Fondario in Public Health Reports
title: Gaussian Mixture Models and Neural Networks for Automatic Speaker Identification
Creators: name: Chalkapally, Usha Gayatri
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 2006

description: Automatic Speaker Recognition is the process of automatically recognizing who is speaking on the basis of individual information contained in speech signals. This technique of Automatic Speaker Recognition makes it possible to use the speaker's voice to verify their identity and control access to services such as voice dialing, banking by telephone, telephone shopping, database access services, information services, voice mail, security control for confidential information areas, and remote access to computers.

In this thesis, the techniques of Gaussian Mixture Models and Neural Networks for Automatic Speaker Identification are presented. Algorithms for Speaker Identification using Gaussian Mixture Models were developed, using both full covariance matrices and diagonal covariance matrices and were tested on the NTIMIT and SPIDRE databases. Experiments were also conducted using the existing neural network — Binary-Pair Partitioned on the NTIMIT and SPIDRE databases.

GMMs are trained with the maximum likelihood approach to give good models for each speaker. In contrast, NNs are trained to discriminate between speakers but form no explicit models for each speaker. It is conjectured that an appropriate combination of maximum likelihood and discriminative training, using both GMMs and NNs should give a better recognition rate than either method alone. Thus, fusion approaches to combine the Gaussian Mixture Models and neural networks for Speaker ID are proposed and tested for various cases. Comparisons of the best results obtained with each method were made for all the cases that were evaluated.

From the comparison of the results obtained with the GMMs alone, NNs alone, and combined GMM/NN, it was observed that the results obtained with GMM alone yielded the best recognition accuracy. The best accuracy using the NTIMIT database was 89.2% on the test data, and the best accuracy using the SPIDRE database was 86.7% on the test data, both results obtained using GMMs alone.
Online supplementary file 5 - Supplemental material for A Thematic Analysis of Overdose Prevention and Response Efforts in States Experiencing Declines in Rates of Opioid-Involved Overdose Deaths
Creators: name: Robinson, Amber B.
name: Ali, Nida
name: Costa, Olga
name: Rooks-Peck, Cherie
name: Sorensen-Alawad, Amy
name: Ballard, Jonathan
name: Lowerre, Kathryn
name: Fondario, Anna
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, Online supplementary file 5, for A Thematic Analysis of Overdose Prevention and Response Efforts in States Experiencing Declines in Rates of Opioid-Involved Overdose Deaths by Amber B. Robinson, Nida Ali, Olga Costa, Cherie Rooks-Peck, Amy Sorensen-Alawad, Jonathan Ballard, Kathryn Lowerre and Anna Fondario in Public Health Reports
Examining College Students' Adoption of Chatbots for Assignment Assistance: From Printed Pages to AI Interfaces
Creators: name: A, Subaveerapandiyan
name: Kataria, Sanjay
name: S., Radhakrishnan
name: S. V., Karthiga
Publisher: name: IGI Global
Year: 2024

description: This study compares college students' adoption of chatbots for assignment assistance with traditional printed books. Objectives include analysing usage patterns, exploring motivations, identifying challenges, examining preferences, and gathering recommendations for chatbot enhancements in academic settings. A robust questionnaire was developed iteratively, including self-evaluation and a pilot study. Data was collected from 573 college students through Google Forms, ensuring diverse representation across academic years and fields of study. While students rely on printed books for assignments moderately, they are more inclined toward chatbots. Key motivations include technological curiosity (62.1%), quick information access (85.3%), and dissatisfaction with traditional methods (64.6%). Challenges include inaccuracies in chatbot responses (86.9%) and conversational limitations (81.2%). There's a clear preference for chatbots in various academic aspects, scoring significantly higher in convenience, speed, and overall impact.
Additional file 1 of Efficacy of a virtual reality-based cognitive interactive training program for children with traumatic brain injuries: study protocol for a parallel-group randomized controlled trial
Creators: name: Shen, Jiabin
name: Wang, Yan
name: Quinn, Susan
name: Suskauer, Stacy J.
name: Birch, Julia
name: Busch, Tyler
name: Svingos, Adrian
name: Crawfis, Roger
name: Yeates, Keith Owen
name: Taylor, H. Gerry
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. SPIRIT Figure.
Lymph-borne CD8α+ dendritic cells are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells
Creators: name: Cerovic, V.
name: Houston, S. A.
name: Westlund, J.
name: Utriainen, L.
name: Davison, E. S.
name: Scott, C. L.
name: Bain, C. C.
name: Joeris, T.
name: Agace, W. W.
name: Kroczek, Richard
name: Mowat, A. M.
name: Yrlid, U.
name: Milling, S. W. F.
Publisher: name: Robert Koch-Institut
Year: 2014
Subjects: subject: Animals
subject: Mice
subject: Mice Inbred C57BL
subject: Mice Knockout
subject: Mice Transgenic
subject: Dendritic Cells/immunology
subject: Ovalbumin/immunology
subject: Cell Proliferation/drug effects
subject: Cells Cultured
subject: Antigens/immunology
subject: Antigens CD8/metabolism
subject: CD8-Positive T-Lymphocytes/immunology
subject: Cell Movement/drug effects
subject: Cell Movement/genetics
subject: Cross-Priming/drug effects
subject: Cross-Priming/genetics
subject: Imidazoles/administration & dosage
subject: Imidazoles/pharmacology
subject: Interferon-gamma/metabolism
subject: Intestinal Mucosa/immunology
subject: Lymph/immunology
subject: Lymphocyte Activation/drug effects
subject: Lymphocyte Activation/genetics
subject: Membrane Glycoproteins/agonists
subject: Ovalbumin/genetics
subject: Ovalbumin/metabolism
subject: Toll-Like Receptor 7/agonists
subject: 610 Medizin

description: Cross-presentation of cellular antigens is crucial for priming CD8+ T cells, and generating immunity to intracellular pathogens—particularly viruses. It is unclear which intestinal phagocytes perform this function in vivo. To address this, we examined dendritic cells (DCs) from the intestinal lymph of IFABP-tOVA 232-4 mice, which express ovalbumin in small intestinal epithelial cells (IECs). Among lymph DCs (LDCs) only CD103+ CD11b− CD8α+ DCs cross-present IEC-derived ovalbumin to CD8+ OT-I T cells. Similarly, in the mesenteric lymph nodes (MLNs), cross-presentation of IEC–ovalbumin was limited to the CD11c+ MHCIIhi CD8α+ migratory DCs, but absent from all other subsets, including the resident CD8αhi DCs. Crucially, delivery of purified CD8α+ LDCs, but not other LDC subsets, into the MLN subcapsular lymphatic sinus induced proliferation of ovalbumin-specific, gut-tropic CD8+ T cells in vivo. Finally, in 232-4 mice treated with R848, CD8α+ LDCs were uniquely able to cross-prime interferon γ-producing CD8+ T cells and drive their migration to the intestine. Our results clearly demonstrate that migrating CD8α+ intestinal DCs are indispensable for cross-presentation of cellular antigens and, in conditions of inflammation, for the initial differentiation of effector CD8+ T cells. They may therefore represent an important target for the development of antiviral vaccinations.
Lesson Plan: Research Resources for Landscape Architecture Students
Creators: name: Frank, Cynthia
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Libraries
subject: Teaching--Aids and devices
subject: Teaching
subject: Landscape architecture
subject: Universities and colleges

description: Seminar session in the library, with all students and librarian sitting around the same table. Librarian has large monitor and computer on a cart, positioned next to the table. The library home page is open. Students are encouraged to ask questions throughout the session. Review the library's various resources for research, including databases, Interlibrary loan, Google scholar. Prepared for Landscape Architecture graduate students, with many links to University fo Maryland Library resources.
sj-pdf-1-cps-10.1177_00104140211024301 – Supplemental Material for Economic Distress and Support for Radical Right Parties—Evidence From Sweden
Creators: name: Dehdari, Sirus H.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material, sj-pdf-1-cps-10.1177_00104140211024301 for Economic Distress and Support for Radical Right Parties—Evidence From Sweden by Sirus H. Dehdari in Comparative Political Studies
Lesson Plan: Research Resources for Landscape Architecture Students
Creators: name: Frank, Cynthia
Publisher: name: unknown
Year: 2024
Subjects: subject: Teaching
subject: Libraries
subject: Teaching--Aids and devices
subject: Universities and colleges
subject: Landscape architecture

description: Seminar session in the library, with all students and librarian sitting around the same table. Librarian has large monitor and computer on a cart, positioned next to the table. The library home page is open. Students are encouraged to ask questions throughout the session. Review the library's various resources for research, including databases, Interlibrary loan, Google scholar. Prepared for Landscape Architecture graduate students, with many links to University fo Maryland Library resources.
Exploring Galaxy Properties of eCALIFA with Contrastive Learning
Creators: name: Martínez-Solaeche, G.
name: García-Benito, R.
name: Delgado, R. M. González
name: Díaz-García, Luis
name: Sánchez, S. F.
name: Conrado, A. M.
name: Rodríguez-Martín, J. E.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Contrastive learning (CL) has emerged as a potent tool for building meaningful latent representations of galaxy properties across a broad spectrum of wavelengths, ranging from optical and infrared to radio frequencies. These representations facilitate a variety of downstream tasks, including galaxy classification, similarity searches, and parameter estimation, which is why they are often referred to as foundation models. In this study, we employ CL on the latest extended DR from CALIFA survey, which encompasses 895 galaxies with enhanced spatial resolution. We demonstrate that CL can be applied to IFU surveys, even with small training sets, to meaningful embedding where galaxies are well-separated based on their physical properties. We discover that the strongest correlations in the embedding space are observed with the EW of Ha morphology, stellar metallicity, age, stellar surface mass density, the [NII]/Ha ratio, and stellar mass, in descending order of correlation strength. Additionally, we illustrate the feasibility of unsupervised separation of galaxy populations along the SFMS, successfully identifying the BC and the RS in a two-cluster scenario, and the GV population in a three-cluster scenario. Our findings indicate that galaxy luminosity profiles have minimal impact on the construction of the embedding space, suggesting that morphology and spectral features play a more significant role in distinguishing between galaxy populations. Moreover, we explore the use of CL for detecting variations in galaxy population distributions across different environments, including voids, clusters, filaments and walls. Nonetheless, we acknowledge the limitations of the CL and our specific training set in detecting subtle differences in galaxy properties, such as the presence of an AGN or other minor scale variations that exceed the scope of primary parameters like stellar mass or morphology.
description: 21 pages, 12 figures
Learning Multimodal Confidence for Intention Recognition in Human-Robot Interaction
Creators: name: Zhao, Xiyuan
name: Li, Huijun
name: Miao, Tianyuan
name: Zhu, Xianyi
name: Wei, Zhikai
name: Song, Aiguo
Publisher: name: arXiv
Year: 2024
Subjects: subject: Robotics (cs.RO)
subject: Human-Computer Interaction (cs.HC)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: The rapid development of collaborative robotics has provided a new possibility of helping the elderly who has difficulties in daily life, allowing robots to operate according to specific intentions. However, efficient human-robot cooperation requires natural, accurate and reliable intention recognition in shared environments. The current paramount challenge for this is reducing the uncertainty of multimodal fused intention to be recognized and reasoning adaptively a more reliable result despite current interactive condition. In this work we propose a novel learning-based multimodal fusion framework Batch Multimodal Confidence Learning for Opinion Pool (BMCLOP). Our approach combines Bayesian multimodal fusion method and batch confidence learning algorithm to improve accuracy, uncertainty reduction and success rate given the interactive condition. In particular, the generic and practical multimodal intention recognition framework can be easily extended further. Our desired assistive scenarios consider three modalities gestures, speech and gaze, all of which produce categorical distributions over all the finite intentions. The proposed method is validated with a six-DoF robot through extensive experiments and exhibits high performance compared to baselines.
Merowingerzeitliche Siedlungsspuren bei der Martinskirche in Gruibingen
Creators: name: Lang, Walter
name: Schreg, Rainer
Publisher: name: Humanities Commons
Year: 1999
Subjects: subject: Villages
subject: Archaeology, Medieval

description: “Relics of a Merovingian Settlement near St.Martin’s Church at Gruibingen” In the center of Gruibingen relics of settlement activities starting in merovingian period have been excavated and provide insights in the genesis of the village. The site is situated close to the church St. Martin where former excavations proofed the existence of rich merovingian burials.”