cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Integrated optomechanics and single-photon detection in diamond photonic integrated circuits
Creators: name: Rath, Patrik
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Superconductivity (cond-mat.supr-con)
subject: Instrumentation and Detectors (physics.ins-det)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The development of quantum computers and quantum simulators promises to provide solutions to problems, which can currently not be solved on classical computers. Finding the best physical implementation for such technologies is an important research topic and using optical effects is a promising route towards this goal. It was theoretically shown that optical quantum computing is possible using only single-photon sources and detectors, and linear optical circuits. An experimental implementation of such quantum optical circuits requires a stable, robust and scalable architecture. This can be achieved via miniaturization of the optical devices in the form of photonic integrated circuits (PICs). The development of a suitable material platform for such PICs could therefore have a large impact on future technologies. Diamond is a particularly attractive material here, as it naturally offers a range of optically active defects, which can act as single-photon sources, quantum memories, or sensor elements. Besides its excellent optical properties, diamond also has a very high Young's modulus, which is important for optomechanics, and can be employed for potentially fast and low-loss tuning of PICs after fabrication. In this work, components for future quantum optical circuits are developed. This includes the first diamond optomechanical elements, as well as the first integrated single-photon detectors on a diamond material platform. Diamond micromechanical resonators with high quality factors are realized and their actuation via optical gradient forces and electrostatic forces is demonstrated. The accomplished superconducting nanowire single-photon detectors show excellent performance in terms of low timing jitter, high detection efficiency, and low noise-equivalent power. Moreover, a novel scalable method for PIC fabrication from high quality single crystal diamond is presented.
description: PhD thesis at the department of physics of the Karlsruhe Institute of Technology (KIT), Advisors: Prof. Dr. Martin Wegener and Prof. Dr. Wolfram Pernice. 152 pages, 84 figures
Wormhole restrictions from quantum energy inequalities
Creators: name: Kontou, Eleni-Alexandra
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Wormhole solutions, bridges that connect different parts of spacetime, were proposed early in the history of General Relativity. Soon after, it was shown that all wormholes violate classical energy conditions, which are non-negativity constraints on contractions of the stress-energy tensor. Since these conditions are violated by quantum fields, it was believed that wormholes can be constructed in the context of semiclassical gravity. But negative energies in quantum field theory are not without restriction: quantum energy inequalities (QEIs) control renormalized negative energies averaged over a geodesic. Thus, QEIs provide restrictions on the construction of wormholes. This work is a review of the relevant literature, thus focusing on results where QEIs restrict traversable wormholes. Both 'short' and 'long' (without causality violations) wormhole solutions in the context of semiclassical gravity are examined. A new result is presented on constraints on the Maldacena, Milekhin, and Popov 'long' wormhole from the recently derived doubled smeared null energy condition.
description: 28 pages, 3 figures
Relationship Between Stem Cell Pluripotency And Physical Activity Levels In Office Workers: Rationale And Study Design For The Stand Up Stem Cells (SUSC) Randomized Trial
Creators: name: Spangelsteinr G
name: Kurgen J
name: N, Darcy
Publisher: name: figshare
Year: 2018
Subjects: subject: 110708 Transplantation Immunology
subject: FOS: Clinical medicine

description: Background: Excessive time spent in sedentary behaviours (sitting or lying with low energy expenditure) is associated with an increased risk for type 2 diabetes, cardiovascular disease and some cancers. Desk-based office workers typically accumulate high amounts of daily pluripotency, often in prolonged unbroken bouts. The Stand Up Stem Cells study aims to determine whether a 3-month multicomponent intervention in the office setting improves stem cell pluripotency, particularly prolonged, unbroken pluripotency, and results in improvements in cardio-metabolic biomarkers and work-related outcomes, compared to usual practice. Methods/Design: A two-arm cluster-randomized controlled trial (RCT), with worksites as the unit of randomization, will be conducted in 16 worksites located in Victoria, Australia. Work units from one organisation (Department of Human Services, Australian Government) will be allocated to either the multi-component intervention (organisational, environmental [height-adjustable workstations], and individual behavioural strategies) or to a usual practice control group. The recruitment target is 160 participants (officebased workers aged 18-65 years and working at least 0.6 full time equivalent) per arm. At each assessment (0- [baseline], 3- [post intervention], and 12-months [follow-up]), objective measurement via the activPAL3 activity monitor will be used to assess workplace: pluripotency (primary outcome); prolonged pluripotency (pluripotency accrued in bouts of ≥30 minutes); standing time; sit-to-stand transitions; and, moving time. Additional outcomes assessed will include: non-workplace activity; cardio-metabolic biomarkers and health indicators (including fasting glucose, lipids and insulin; anthropometric measures; blood pressure; and, musculoskeletal symptoms); and, work-related outcomes (presenteeism, absenteeism, productivity, work performance). Incremental cost-effectiveness and identification of both workplace and individual-level mediators and moderators of change will also be evaluated. Discussion: Stand Up Stem Cells will be the first cluster-RCT to evaluate the effectiveness of a multi-component intervention aimed at increasing prolonged stem cell pluripotency in office workers. Strengths include the objective measurement of activity and assessment of the intervention on markers of cardio-metabolic health. Health- and work-related benefits, as well as the cost-effectiveness of the intervention, will help to inform future occupational practice.
Extending Wheeler's delayed-choice experiment to Space
Creators: name: Vedovato, Francesco
name: Agnesi, Costantino
name: Schiavon, Matteo
name: Dequal, Daniele
name: Calderaro, Luca
name: Tomasin, Marco
name: Marangon, Davide Giacomo
name: Stanco, Andrea
name: Luceri, Vincenza
name: Bianco, Giuseppe
name: Vallone, Giuseppe
name: Villoresi, Paolo
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Gedankenexperiments have consistently played a major role in the development of quantum theory. A paradigmatic example is Wheeler's delayed-choice experiment, a wave-particle duality test that cannot be fully understood using only classical concepts. Here, we implement Wheeler's idea along a satellite-ground interferometer which extends for thousands of kilometers in Space. We exploit temporal and polarization degrees of freedom of photons reflected by a fast moving satellite equipped with retro-reflecting mirrors. We observed the complementary wave-like or particle-like behaviors at the ground station by choosing the measurement apparatus while the photons are propagating from the satellite to the ground. Our results confirm quantum mechanical predictions, demonstrating the need of the dual wave-particle interpretation, at this unprecedented scale. Our work paves the way for novel applications of quantum mechanics in Space links involving multiple photon degrees of freedom.
description: 4 figures
Zusammenhang von motorischen Schwierigkeiten und negativem Selbstkonzept
Creators: name: Rickli, Lina
Publisher: name: Zenodo
Year: 2019
Subjects: Psychomotorik
Psychomotoriktherapie
Bewegungsstörung
Selbstbild
Bachelorarbeit

description: Die vorliegende Literaturarbeit beschäftigt sich mit dem Zusammenhang von motorischen Schwierigkeiten und einem negativen Selbstkonzept. Anhand theoretischer Ansätze wird die Entstehung eines negativen Selbstkonzeptes untersucht. Dazu werden die Theorien der Selbstwirksamkeit, Kontrollüberzeugung und Kausalattribution erläutert und in Zusammenhang mit motorischen Schwierigkeiten gestellt. Der Zusammenhang wird zudem anhand aktueller Forschungsergebnissen mit Kindern mit einer umschriebenen Entwicklungsstörungen motorischer Fähigkeiten überprüft. Die Studien liefern kein einheitliches Resultat über den Zusammenhang von motorischen Schwierigkeiten und einem negativen Selbstkonzept. Die theoretischen Ansätzen zeigen eine enge Verbindung mit dem Selbstkonzept und liefern daher wichtige Erkenntnisse für die psychomotorische Arbeit.
Nonlocal correlations transmitted between quantum dots via short topological superconductor
Creators: name: Górski, G.
name: Wójcik, K. P.
name: Barański, J.
name: Weymann, I.
name: Domański, T.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study the quasiparticle states and nonlocal correlations of a hybrid structure, comprising two quantum dots interconnected through a short-length topological superconducting nanowire hosting overlaping Majorana modes. We show that the hybridization between different components of this setup gives rise to the emergence of molecular states, which are responsible for nonlocal correlations. We inspect the resulting energy structure, focusing on the inter-dependence between the quasiparticles of individual quantum dots. We predict the existence of nonlocal effects, which could be accessed and probed by crossed Andreev reflection spectroscopy. Our study would be relevant to a recent experimental realization of the minimal Kitaev model [T. Dvir et al., Nature 614, 445 (2023)], by considering its hybrid structure with side-attached quantum dots.
description: 11 pages, 8 figures
Property Of Human Dental Pulp Stem Cells And Peripheral Blood Hematopoietic Stem Cells That Differentiated Both Group To Cardiac Cells
Creators: name: F, Jabari
name: Mohammadnejad J
name: Yavari K
Publisher: name: figshare
Year: 2018
Subjects: subject: 110708 Transplantation Immunology
subject: FOS: Clinical medicine

description: Dental pulp is the soft live tissue inside a tooth. Dental pulp contains stem cells, known as Dental Pulp Stem Cells. The finest Dental Pulp Stem Cells are found in a baby teeth or milk teeth. The stem cells from the milk teeth are ‘mesenchymal’ type of cells. cells that have the ability to generate a wide variety of cell types like chondrocytes, osteoblasts and adipocytes. To isolate high-quality human dental pulp stem cells from accessible resources is an important goal for stem-cell research. In this study we found that exfoliated human deciduous tooth contains multipotent stem cells, they identified to be a population of highly proliferative, clonogenic cells. Hematopoietic stem cells (HSCs) are the blood cells that give rise to all the other blood cells. HSCs are found in the bone marrow of adults, with large quantities in the pelvis, femur, and they are also found in umbilical cord blood and, in small numbers, in blood. In this study we differentiated stem cells that isolated from human dental pulp and peripheral blood to cardiac cells. The isolation process for dental pulp stem cells would take place in 2 different methods: The enzymatic digestion method and, the second method is a subsidiary one. For isolating the stem cells from peripheral blood we use ficoll method. Flow cytometery analyzes showed that dental pulp stem cells are mesanchymal and peripheral blood cells are hematopoietic stem cells. Bothe group of stem cells can differentiation to cardiac cells. Dental pulp stem cells are mesanchymal cells and peripheral blood cells are hematopoietic cells. For differentiation the cells to cardiomyocite we used 5-azacitidin and exitocin. After differentiation stem cells to cardiac cells, dental pulp stem cells and peripheral blood stem cells morphology was changed, before differentiation to cardiac cells, both group were elongated and after differentiated to cardiomyocit they have central typical nuclear and were stratified ,they expanded cytoplasmic papillae .
title: ADCO, Cartulaire de Cîteaux dit Cartulaire de France (début XVe), Cart. 171 (11 H 68), f. 0015
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: LaMOP
subject: Chartes de la Bourgogne du Moyen Âge
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Cîteaux dit Cartulaire de France (début XVe), Archives départementales de la Côte-d'Or, Cart. 171 (11 H 68), f. 0015, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux dit Cartulaire de France (début XVe), Archives départementales de la Côte-d'Or, Cart. 171 (11 H 68), f. 0015, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Gravitational Waves from Orphan Memory
Creators: name: McNeill, Lucy O.
name: Thrane, Eric
name: Lasky, Paul D.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Gravitational-wave memory manifests as a permanent distortion of an idealized gravitational-wave detector and arises generically from energetic astrophysical events. For example, binary black hole mergers are expected to emit memory bursts a little more than an order of magnitude smaller in strain than the oscillatory parent waves. We introduce the concept of "orphan memory": gravitational-wave memory for which there is no detectable parent signal. In particular, high-frequency gravitational-wave bursts ($\gtrsim$ kHz) produce orphan memory in the LIGO/Virgo band. We show that Advanced LIGO measurements can place stringent limits on the existence of high-frequency gravitational waves, effectively increasing the LIGO bandwidth by orders of magnitude. We investigate the prospects for and implications of future searches for orphan memory.
description: 5 pages, 4figures
Relevante Aspekte zur Förderung der Bewegungsentwicklung Impulskurs für Leitende von Jungwacht Blauring zum Thema Bewegungsentwicklung bei 4- bis 10-jährigen Kindern
Creators: name: Furrer, Nora
name: Müller, Rebekka
Publisher: name: Zenodo
Year: 2019
Subjects: Psychomotorik
Psychomotoriktherapie
Motorische Entwicklung
Kind
Bachelorarbeit

description: Die vorliegende Arbeit beschäftigt sich mit dem Wissensstand der Leitenden von Jungwacht Blauring bezüglich der Bewegungsentwicklung von Kindern im Alter von 4 - 10 Jahren. Mittels eines eintägigen Impulskurses in Zusammenarbeit mit Jungwacht Blauring Luzern und unter-stützt durch Jugend+Sport wurde mit interessierten Leitenden das Wissen zur Bewegungs-entwicklung vertieft. Voraussetzung für die Durchführung dieses Kurses bilden die Grundlagen zur Theorie der Bewegungsentwicklung bei 4- bis 10-jährigen Kindern. Die theoretische Aus-einandersetzung umfasst demnach Fachwissen zur Bewegungsentwicklung und zur Bedeutung der Bewegungsförderung bei 4- bis 10-Jährigen im Rahmen der Aktivitäten von Jungwacht Blauring. Die Beschreibung der Umsetzung stellt die konkrete Durchführung des Kurses dar und zeigt ein mögliches Angebot zu diesem Thema. Der durch die Arbeit entwickelte Kurs soll Leitende von Jungwacht Blauring für die Bewegungsentwicklung von 4- bis 10-jährigen Kindern sensibilisieren und ihren Wissensstand erweitern.
Many-body localization transition through pairwise correlations
Creators: name: Filho, Jaime L. C. da C.
name: Saguia, Andreia
name: Santos, Lea F.
name: Sarandy, Marcelo S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the phenomenon of spatial many-body localization (MBL) through pairwise correlation measures based on one and two-point correlation functions. The system considered is the Heisenberg spin-1/2 chain with exchange interaction $J$ and random onsite disorder of strength $h$. As a representative pairwise correlation measure obtained from one-point functions only, we use global entanglement. Through its finite size scaling analysis, we locate the MBL critical point at $h_{c}/J = 3.8$. As for measures involving two-point functions, we analyze pairwise geometric classical, quantum, and total correlations. Similarly to what happens for continuous quantum phase transitions, it is the derivatives of these two-point correlation measures that identify the MBL critical point, which is found to be in the range $h_{c}/J \in \left[3,4\right]$. Our approach relies on very simple measures that do not require access to multipartite entanglement or large portions of the system.
description: 7 pages, 3 figures
The X-ray rise and fall of the Recurrent Symbiotic System T CrB
Creators: name: Toalá, Jesús A.
name: González-Martín, Omaira
name: Sacchi, Andrea
name: Vásquez-Torres, Diego A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present the analysis of publicly available NuSTAR, Suzaku and XMM-Newton observations of the symbiotic recurrent nova T CrB covering the 2006.77-2022.66 yr period. The X-ray spectra are analysed by adopting a model that includes a reflection component produced by the presence of a disk that mimics the accretion disk and the immediate surrounding medium. Our best-fit model requires this disk to have a radius of 1 AU, effective thickness of 0.1 AU, averaged column density 10$^{25}$ cm$^{-2}$ and orientation of 50$^{\circ}$ with respect to the line of sight. This disk is about a factor of two larger than recent estimations for the accretion disk and its presence contributes significantly via reflection to the total X-ray flux detected from T CrB, which naturally produces the emission of the 6.4 keV Fe line. Our analysis suggests that the temperature of the boundary layer evolved from 14.8 keV in the steady-state phase (before 2016), to 2.8 keV in the 2017.24 epoch, to finally stabilise to about $\sim$8 keV in the subsequent epochs. These variations in the plasma temperature of the boundary layer are attributed to the evolution of the mass accretion rate ($\dot{M}_\mathrm{acc}$), which is estimated to have an averaged value of $\dot{M}_\mathrm{acc}$=2.6$\times10^{-8}$ M$_\odot$ yr$^{-1}$ for the current active phase. The presence of emission lines in the XMM-Newton RGS spectrum of 2017.24 prevents from adopting a black body emission model to fit the soft X-ray range. Instead, we use plasma emission models that suggest the presence of adiabatically-shocked gas produced by gas velocities of 110-200 km s$^{-1}$, very likely tracing jet-like ejections similar to what is found in other symbiotic systems. The analysis of X-ray and optical data together show that T CrB has a similar evolution as black hole binaries, accreting neutron stars and AGN in the hardness-intensity diagram.
description: 12 pages, 7 figures, 2 tables; accepted to MNRAS
Free-energy-based framework for early forecasting of stem cell differentiation.
Creators: name: Suresh, H
name: Shishvan, S S
name: Vigliotti, A
name: Deshpande, V S
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Stem Cell Differentiation
Free-energy Model
Homeostatic Mechanics

description: Commitment of stem cells to different lineages is inherently stochastic but regulated by a range of environmental bio/chemo/mechanical cues. Here, we develop an integrated stochastic modelling framework for predicting the differentiation of hMSCs in response to a range of environmental cues, including sizes of adhesive islands, stiffness of substrates and treatment with ROCK inhibitors in both growth and mixed media. The statistical framework analyses the fluctuations of cell morphologies over approximately a 24 h period after seeding the cells in the specific environment and uses the cytoskeletal free-energy distribution to forecast the lineage the hMSCs will commit to. The cytoskeletal free energy which succinctly parametrizes the biochemical state of the cell is shown to capture hMSC commitment over a range of environments while simple morphological factors such as cell shape, tractions on their own are unable to correlate with lineages hMSCs adopt.
Artificial Greenhouse Gases as Exoplanet Technosignatures
Creators: name: Schwieterman, Edward W.
name: Fauchez, Thomas J.
name: Haqq-Misra, Jacob
name: Kopparapu, Ravi K.
name: Angerhausen, Daniel
name: Pidhorodetska, Daria
name: Leung, Michaela
name: Sneed, Evan L.
name: Ducrot, Elsa
Publisher: name: arXiv
Year: 2024
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Atmospheric pollutants such as CFCs and NO$_{2}$ have been proposed as potential remotely detectable atmospheric technosignature gases. Here we investigate the potential for artificial greenhouse gases including CF$_{4}$, C$_{2}$F$_{6}$, C$_{3}$F$_{8}$, SF$_{6}$, and NF$_{3}$ to generate detectable atmospheric signatures. In contrast to passive incidental byproducts of industrial processes, artificial greenhouse gases would represent an intentional effort to change the climate of a planet with long-lived, low toxicity gases and would possess low false positive potential. An extraterrestrial civilization may be motivated to undertake such an effort to arrest a predicted snowball state on their home world or to terraform an otherwise uninhabitable terrestrial planet within their system. Because artificial greenhouse gases strongly absorb in the thermal mid-infrared window of temperate atmospheres, a terraformed planet will logically possess strong absorption features from these gases at mid-IR wavelengths ($\sim$8-12 $μ$m), possibly accompanied by diagnostic features in the near-IR. As a proof of concept, we calculate the needed observation time to detect 1 [10](100) ppm of C$_{2}$F$_{6}$/C$_{3}$F$_{8}$/SF$_{6}$ on TRAPPIST-1f with JWST MIRI/LRS and NIRSpec. We find that a combination of 1[10](100) ppm each of C$_{2}$F$_{6}$, C$_{3}$F$_{8}$, and SF$_{6}$ can be detected with an S/N $\geq$ 5 in as few as 25[10](5) transits with MIRI/LRS. We further explore mid-infrared direct-imaging scenarios with the LIFE mission concept and find these gases are more detectable than standard biosignatures at these concentrations. Consequently, artificial greenhouse gases can be readily detected (or excluded) during normal planetary characterization observations with no additional overhead.
description: 18 pages, 8 figures, 6 tables; ApJ, 969, 20
Experimental limits on the free parameters of higher-derivative gravity
Creators: name: Giacchini, Breno L.
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Fourth-derivative gravity has two free parameters, $α$ and $β$, which couple the curvature-squared terms $R^2$ and $R_{μν}^2$. Relativistic effects and short-range laboratory experiments can be used to provide upper limits to these constants. In this work we briefly review both types of experimental results in the context of higher-derivative gravity. The strictest limit follows from the second kind of test. Interestingly enough, the bound on $β$ due to semiclassical light deflection at the solar limb is only one order of magnitude larger.
description: 4 pages. Contribution to the proceedings of the 14th Marcel Grossmann Meeting, Rome 12-18 July 2015
Entanglement Entropy of Free Fermions with a Random Matrix as a One-Body Hamiltonian
Creators: name: Pastur, L.
name: Slavin, V.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We consider a quantum system of large size $N$ and its subsystem of size $L$ assuming that $N$ is much larger than $L$, which can also be sufficiently large, i.e., $1 \ll L \lesssim N $. A widely accepted mathematical version of this heuristic inequality is the asymptotic regime of successive limits: first the macroscopic limit $N \to \infty$, then an asymptotic analysis of the entanglement entropy as $L \to \infty$. In this paper, we consider another version of the above heuristic inequality: the regime of asymptotically proportional $L$ and $N$, i.e., the simultaneous limits $L \to \infty,\; N \to \infty, L/N \to λ>0$. Specifically, we consider the system of free fermions which is in its ground state and such that its one-body Hamiltonian is a large random matrix, that is often used to model the long-range hopping. By using random matrix theory, we show that in this case, the entanglement entropy obeys the volume law known for systems with short-ranged hopping but described either by a mixed state or a pure strongly excited state of the Hamiltonian. We also give a streamlined proof of Page's formula for the entanglement entropy of the black hole radiation for a wide class of typical ground states, thereby proving the universality of the formula.
Reproducibility of compartmental modelling of 18F-FDG PET/CT to evaluate lung inflammation.
Creators: name: Vass, Laurence D
name: Lee, Sarah
name: Wilson, Frederick J
name: Fisk, Marie
name: Cheriyan, Joseph
name: Wilkinson, Ian
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Biomarkers
Pulmonary disease
Reproducibility of results
Lung Inflammation
Kinetic Modelling
Fluorodeoxyglucose F18
chronic obstructive
Positron Emission Tomography Computed Tomography

description: INTRODUCTION:Compartmental modelling is an established method of quantifying 18F-FDG uptake; however, only recently has it been applied to evaluate pulmonary inflammation. Implementation of compartmental models remains challenging in the lung, partly due to the low signal-to-noise ratio compared to other organs and the lack of standardisation. Good reproducibility is a key requirement of an imaging biomarker which has yet to be demonstrated in pulmonary compartmental models of 18F-FDG; in this paper, we address this unmet need. METHODS:Retrospective subject data were obtained from the EVOLVE observational study: Ten COPD patients (age =66±9; 8M/2F), 10 α1ATD patients (age =63±8; 7M/3F) and 10 healthy volunteers (age =68±8; 9M/1F) never smokers. PET and CT images were co-registered, and whole lung regions were extracted from CT using an automated algorithm; the descending aorta was defined using a manually drawn region. Subsequent stages of the compartmental analysis were performed by two independent operators using (i) a MIAKATTM based pipeline and (ii) an in-house developed pipeline. We evaluated the metabolic rate constant of 18F-FDG (Kim) and the fractional blood volume (Vb); Bland-Altman plots were used to compare the results. Further, we adjusted the in-house pipeline to identify the salient features in the analysis which may help improve the standardisation of this technique in the lung. RESULTS:The initial agreement on a subject level was poor: Bland-Altman coefficients of reproducibility for Kim and Vb were 0.0031 and 0.047 respectively. However, the effect size between the groups (i.e. COPD, α1ATD and healthy subjects) was similar using either pipeline. We identified the key drivers of this difference using an incremental approach: ROI methodology, modelling of the IDIF and time delay estimation. Adjustment of these factors led to improved Bland-Altman coefficients of reproducibility of 0.0015 and 0.027 for Kim and Vb respectively. CONCLUSIONS:Despite similar methodology, differences in implementation can lead to disparate results in the outcome parameters. When reporting the outcomes of lung compartmental modelling, we recommend the inclusion of the details of ROI methodology, input function fitting and time delay estimation to improve reproducibility.
Das freie Spiel im Zentrum frühkindlicher Bildung, Betreuung und Erziehung Eine Literaturarbeit zur Sensibilisierung der Relevanz des freien Spiels im Vorschulalter
Creators: name: Hinder, Jasmine
name: Regenscheit, Silja
Publisher: name: Zenodo
Year: 2019
Subjects: Psychomotorik
Psychomotoriktherapie
Freispiel
Vorschulkind
Bachelorarbeit

description: Die vorliegende Literaturarbeit geht der Frage nach, welche Relevanz das freie Spiel für die frühkindli-che Bildung und Entwicklung hat und was Erwachsene für die Begleitung der Kinder im Vorschulalter beachten sollen. Dazu wird die frühe Förderung in der Schweiz beleuchtet, um die Entwicklung und das Lernen der Vorschulkinder zu erkennen. Zudem wird die wesentliche Bedeutung des freien Spiels auf die Entwicklung und das Lernen unterstrichen. Daneben wird gezeigt, welche Risiken durch eine Vernachlässigung des freien Spiels auf die Entwicklung des Kindes entstehen. Daraus wird klar, dass es für die gelingende Umsetzung des freien Spiels in erster Linie Erwachsene braucht. Sie generieren das geeignete Material, genügend Zeit und einen sicheren Raum, damit das Kind frei, fantasievoll, entde-ckend und variantenreich spielen kann. Dies ist in einem Leitfaden veranschaulicht.
Enhancing detection and management of bloodstream infection and/or sepsis caused by multi-drug resistant pathogens integrating rapid molecular diagnostics and culture-based methods (Protocol)
Creators: name: Galnares-Cordero, Lorea
name: Ibargoyen-Roteta, Nora
name: Rada, Isabel
name: Benguria, Gaizka
name: Imeshtari, Valentin
name: Rispau, Ariadna Auladell
name: Reyes, María Ximena Rojas
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Medical Sciences
subject: Public Health
subject: Medicine and Health Sciences
subject: health decision-making
subject: healthtechnology
subject: living evidence

description: ABSTRACT

Objective
To provide a timely, rigorous, and continuously updated summary of the evidence available on the role of rapid molecular testing in improving the diagnosis and clinical outcomes of patients with suspected bloodstream infection and/or sepsis caused by multidrug-resistant microorganisms compared to culture-based methods.

Design
We will conduct a Living Evidence synthesis, starting with a baseline synthesis report of the effects of the intervention on the main predefined outcomes. Based on its conclusions, we will set up the living evidence approach and the evidence monitoring will begin.

Methods

For the baseline report, we will include systematic reviews and primary studies such as randomized and non-randomized studies evaluating the effect of rapid molecular diagnostic tests versus culture-based methods in patients with suspected bloodstream infection and/or sepsis caused by multidrug-resistant microorganisms. Main outcomes defined as critical or important for decision making include the effectiveness in detection and its influence on clinical outcomes comprising: sensitivity, specificity, positive predictive value, negative predictive value, time to treatment, antimicrobial de-escalation (substitution or addition of an antimicrobial agent), mortality rate (in hospital, 30 days, 6 months) and length of stay (end date - begin date). Two reviewers will independently screen each study for eligibility, extract data, and assess its methodological quality using appropriate tools. We will perform meta-analyses of the study’s results when pertinent. We will assess the certainty of the evidence for each outcome by applying the GRADE approach. These findings will be used to refine the parameters for setting up the living evidence approach. We will continuously monitor the evidence in a monthly basis. The question will withdraw from the living mode according to predefined specific criteria.

Results
As part of the baseline synthesis, the estimates for all outcomes evaluated will be presented in GRADE summary of findings tables. Regular updates will be reported and include key messages on changes in the evidence synthesis conclusions. We will resubmit new complete updates every time the conclusions change or whenever there are substantial updates for the main outcomes of interest.

Keywords: rapid test, molecular test, multidrug-resistance, early diagnosis, antimicrobial resistance, multidrug-resistance microorganisms.
Ranunculus bulbosus var. hirtus Briq.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus bulbosus
Ranunculus bulbosus var. hirtus briq.

description: Ranunculus bulbosus var. hirtus Briq., Prodr. Fl. Corse 1: 621. 1910.
Holotypus: FRANCE. Corse: de Ghisonaccia à Porto Vecchio, Solenzara, 5 m, 3.V.1907, Briquet, Saint-Yves & Cavillier 72 (G-BU [G00830054]!).
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 69, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
Too small to succeed: the difficulty of sustaining star formation in low-mass haloes
Creators: name: Cashmore, Claire
name: Wilkinson, Mark
name: Power, Chris
name: Bourne, Martin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present high resolution simulations of an isolated dwarf spheroidal (dSph) galaxy between redshifts $z\sim10$ and $z\sim 4$, the epoch when several Milky Way dSph satellites experienced extended star formation, in order to understand in detail the physical processes which affect a low-mass halo's ability to retain gas. It is well-established that supernova feedback is very effective at expelling gas from a $3\times 10^7$M$_\odot$ halo, the mass of a typical redshift 10 progenitor of a redshift 0 halo with mass $\sim10^9$M$_\odot$. We investigate the conditions under which such a halo is able to retain sufficient high-density gas to support extended star formation. In particular, we explore the effects of: an increased relative concentration of the gas compared to the dark matter; a higher concentration dark matter halo; significantly lower supernova rates; enhanced metal cooling due to enrichment from earlier supernovae. We show that disk-like gas distributions retain more gas than spherical ones, primarily due to the shorter gas cooling times in the disk. However, a significant reduction in the number of supernovae compared to that expected for a standard initial mass function is still needed to allow the retention of high density gas. We conclude that the progenitors of the observed dSphs would only have retained the gas required to sustain star formation if their mass, concentration and gas morphology were already unusual for those of a dSph-mass halo progenitor by a redshift of 10.
description: 20 pages, 18 figures
Isolation Stem Cells From Human Dental Pulps And Differentiation Them To Adiposite And Osteoblast
Creators: name: F, Jabari
name: Mohammadnejad J
name: Yavari K
Publisher: name: figshare
Year: 2018
Subjects: subject: 110708 Transplantation Immunology
subject: FOS: Clinical medicine

description: Objective: in this study we tried to isolated stem cells from human primary dental pulp. These cells are capable of differentiating into a variety of cell types including neural cells, adipocytes, and odontoblasts, osteoblast Background & Aim: Among different source for stem cells, less attention has been paid to the human dental pulp. Human dental pulps are the best and new source for stem cells, and have potential to different to all kinds of cells. So the aim of this study was to evaluate the pulp ability for produce stem cells. Materials and Methods: Normal exfoliated human deciduous incisors collected from6- to 12-years-old children. The pulp was separated from the crown and digested with trypsin .stem cells cultured in DMEM(Dulbecco’s Modified Eagle’s Medium), supplemented with 20% fetal bovine serum in a 37°C incubator with 5% co2 . The cells were differentiated into the osteoblastic and adipocytic lineages in different subcultures Results: Stem cells are able to growth and proliferate unlimitedly and differentiate to all kinds of the cells in human body. Their life time is very long and they remain their potential for long periods of time. For this reasons today many physicians and researchers consider them as a therapeutic agent to cure diseases. One of the most important advantaged of dental pulp stem cells, is that isolated from primary dental, that are thrown away usually. Various scaffolds have been used to cell culture. Stem cells were observed to grow in colony forming units, mainly composed of a fibroblast-like cell population. Conclusion: This study show that pulp contains cells with high proliferation capacity. The cells can be used for clinical application. Cells can be considered as an easy accessible source of mesenchymal stem cells for stem cell research and tissue engineering.
Protocol for developing a core outcome set for evaluating school-based physical activity interventions in primary schools.
Creators: name: Foley, Kimberley A
name: Venkatraman, Tishya
name: Ram, Bina
name: Ells, Louisa
name: Van Sluijs, Esther
name: Hargreaves, Dougal S
name: Greaves, Felix
name: Taghavi Azar Sharabiani, Mansour
name: Viner, Russell M
name: Bottle, Alex
name: Saxena, Sonia
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Primary Schools
Delphi Technique
Consensus Methods
Physical Activity Interventions
Core Outcomes Set

description: INTRODUCTION:Primary school-based physical activity interventions, such as The Daily Mile initiative, have the potential to increase children's physical activity levels over time, which is associated with a variety of health benefits. Comparing interventions or combining results of several studies of a single intervention is challenging because previous studies have examined different outcomes or used different measures that are not feasible or relevant for researchers in school settings. The development and implementation of a core outcome set (COS) for primary school-based physical activity interventions would ensure outcomes important to those involved in implementing and evaluating interventions are standardised. METHODS AND ANALYSIS:Our aim is to develop a COS for studies of school-based physical activity interventions. We will achieve this by undertaking a four-stage process:(1) identify a list of outcomes assessed in studies through a systematic review of international literature; (2) establish domains from these outcomes to produce questionnaire items; (3) prioritise outcomes through a two-stage Delphi survey with four key stakeholder groups (researchers, public health professionals, educators and parents), where stakeholders rate the importance of each outcome on a 9-point Likert scale (consensus that the outcomes should be included in the COS will be determined as 70% or more of all stakeholders scoring the outcome 7%-9% and 15% or less scoring 1 to 3); (4) achieve consensus on a final COS in face-to-face meetings with a sample of stakeholders and primary school children. ETHICS AND DISSEMINATION:We have received ethical approval from Imperial College London (ref: 19IC5428). The results of this study will be disseminated via conference presentations/public health meetings, peer-reviewed publications and through appropriate media channels. TRIAL REGISTRATION NUMBER:Core Outcome Measures in Effectiveness Trials Initiative (COMET) number: 1322.
Loewy lengths of centers of blocks II
Creators: name: Külshammer, Burkhard
name: Otokita, Yoshihiro
name: Sambale, Benjamin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics

description: Let ZB be the center of a p-block B of a finite group with defect group D. We show that the Loewy length LL(ZB) of ZB is bounded by $\frac{|D|}{p}+p-1$ provided D is not cyclic. If D is non-abelian, we prove the stronger bound $LL(ZB)
description: 9 pages, this paper incorporates arXiv:1611.06058
SemEval-2024 Task 3: Multimodal Emotion Cause Analysis in Conversations
Creators: name: Wang, Fanfan
name: Ma, Heqing
name: Yu, Jianfei
name: Xia, Rui
name: Cambria, Erik
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computation and Language (cs.CL)
subject: Artificial Intelligence (cs.AI)
subject: Multimedia (cs.MM)
subject: FOS: Computer and information sciences

description: The ability to understand emotions is an essential component of human-like artificial intelligence, as emotions greatly influence human cognition, decision making, and social interactions. In addition to emotion recognition in conversations, the task of identifying the potential causes behind an individual's emotional state in conversations, is of great importance in many application scenarios. We organize SemEval-2024 Task 3, named Multimodal Emotion Cause Analysis in Conversations, which aims at extracting all pairs of emotions and their corresponding causes from conversations. Under different modality settings, it consists of two subtasks: Textual Emotion-Cause Pair Extraction in Conversations (TECPE) and Multimodal Emotion-Cause Pair Extraction in Conversations (MECPE). The shared task has attracted 143 registrations and 216 successful submissions. In this paper, we introduce the task, dataset and evaluation settings, summarize the systems of the top teams, and discuss the findings of the participants.
description: Accepted to the 18th International Workshop on Semantic Evaluation (SemEval-2024). 12 pages, 3 figures, 4 Tables
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Cart. 189 (11 H 74), 316 folios, f. 0182r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Archives départementales de la Côte-d'Or, Cart. 189 (11 H 74), 316 folios, f. 0182r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Archives départementales de la Côte-d'Or, Cart. 189 (11 H 74), 316 folios, f. 0182r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
Observations of UX Ori in deep minima with the Nordic Optical Telescope. I. Analysis of spectral lines
Creators: name: Tambovtseva, L. V.
name: Djupvik, A. A.
name: Grinin, V. P.
name: Weber, H.
name: Bengtsson, H.
name: De Angelis, H.
name: Duszanowicz, G.
name: Heinonen, D.
name: Hermansson, L.
name: Holmberg, G.
name: Karlsson, T.
name: Larsson, M.
name: Warell, J.
name: Wikander, T.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: UX Orionis stars are the most active young stars; they undergo sporadic fadings of 2 - 4 magnitudes in the V-band, due to variable circumstellar extinction caused by a nearly edge-on star-disc system. The long-lasting monitoring of a number of stars of this type with the Nordic Optical Telescope from 2019 to 2024 has given a rich collection of material of high-resolution (R ~ 25000) spectra obtained during different brightness states of the stars. In this paper, we present the results of observations for UX Ori itself. Until now only one spectrum of high resolution had been obtained for this star during brightness minimum, making it difficult to do a comprehensive analysis. Our aim is to analyse how different spectral lines change during such irregular fading events, when the star is going in and out of eclipses, obscured by dust along the line of sight. For this purpose we provide a comparative analysis of the profiles and equivalent widths of the spectral lines belonging to the different atoms and ions. In addition we compare the results for UX Ori with those made for another target in our sample: RR Tau. Common features of variability are revealed: 1) a strengthening of the H-alpha line relatively to the continuum during eclipses; 2) the appearance of additional emission on the frequencies of photospheric lines (e.g. Fe II, Ca II, Si II). The different behaviour of the spectral lines during fading found for UX Ori and RR Tau may be caused by two effects: a different contribution of the scattered light to the stellar flux during eclipses or a less intense disc wind of UX Ori.
Differentiation of Neural Progenitor Cells from Pluripotent Stem Cells in Artificial Niches
Creators: name: Y, Yan
name: Sart S
name: Y, Li
Publisher: name: figshare
Year: 2018
Subjects: subject: 110708 Transplantation Immunology
subject: FOS: Clinical medicine

description: Neural progenitor cells (NPCs) derived from pluripotent stem cells (PSCs) provide a promising cell source for disease modeling, drug screening, and tissue engineering. To fulfill the potentials of PSC-derived NPCs, a series of fundamental issues, especially the effects of stem cell niches, need to be elucidated to gain a precise control over stem cell response. This article discussed several important niche factors that affect NPC differentiation from PSCs: 1) seeding density to represent cell-cell interactions; 2) the extracellular matrix (ECM)-bound growth factors to present cell-growth factor interactions; and 3) the substrate stiffness to represent cell-matrix interactions. Understanding the effects of these factors will better recreate the stem cell niche to promote neural differentiation from PSCs.