cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Three essays in health economics and public policy
Creators: name: Milliken, Olga V
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Economics, General.
subject: Political Science, General.
subject: Sociology, Public and Social Welfare.
subject: Health Sciences, Health Care Management.

description: Essay One: Genetic Health Risks: The Case for Universal Public Health Insurance. This paper examines the appropriate role for the public sector in providing genetic and health insurance when health risks are genetically determined at conception. The ex ante efficient outcome (when individuals are ignorant about their health risks) is characterized. It is demonstrated that this outcome cannot be achieved by private health insurance markets or by a government which cannot commit to a once-and-for-all transfer policy. In contrast, the desired outcome is attained through public provision of universal health insurance and of genetic testing, coupled with a public pension scheme. Essay Two: Fee-for-Service vs. Capitation: Anything You Can Do - I Can Do Better (and Cheaper). This paper recasts the analysis of optimal physician remuneration - generally presented as a contest between prospective (capitation) and retrospective (fee-for-service) schemes - as a problem in price theory. This approach abstracts from problems of asymmetric information and concentrates on the design of the price mechanism. It demonstrates that when the demand for health care is price-inelastic, the appropriately designed fee-for-service and capitation schemes both lead to Pareto efficient outcomes. When a patient's demand for care is uncertain, or the risk of poor health outcomes depends on the preventive care provision, standard arguments concerning risk bearing are used to prove that paying physicians on a fee-for-service basis can deliver socially-optimal outcomes at a lower cost than if they are paid under a capitation scheme. Essay Three: Comparative Efficiency Assessment of Primary Care Models Using Data Envelopment Analysis. This paper compares the productive efficiency of four models of primary care service delivery in Ontario, Canada, using the methodology of Data Envelopment Analysis. Particular care is taken to include quality of service in the output measure. The influence of the delivery model on productive efficiency is disentangled from patient characteristics using regression analysis. The traditional fee-for-service arrangement ranks highest and the Community Health Centre model (which involves a multidisciplinary team of health care professionals paid on a salary basis) the lowest in efficiency scoring. The reliance of input measures on the costs of running a practice and on the number of patients favours the fee-for-service model.
Biological and molecular studies on potatovirus interactions using Potato virus S and Potato virus Y as model systems
Creators: name: Naveed, Khalid
Publisher: name: Washington State University
Year: 2013
Subjects: Potatoes -- Diseases and pests -- Molecular aspects

description: Potato (Solanum tuberosum L.) is a staple food in the world. Potato virus Y (PVY; Potyvirus: Potyviridae) is an important virus that affects yield and quality of potatoes. PVY exists as biologically distinct strains: PVY-N induces systemic veinal necrosis in tobacco, PVY-O causes hypersensitive response (HR) in potato cultivars carrying the Ny gene and PVY-NTN produces necrotic rings on the tubers of sensitive potato cultivars. The vsiRNA profiles of three distinct PVY strains, ordinary (PVY-O), tobacco-veinal necrotic (PVY-N) and tuber-necrotic (PVY-NTN) strains were determined in potato cv. Russet Burbank. The frequency and distribution of vsiRNAs varied among different strains. PVY-NTN infected plants accumulated the highest population of PVY-vsiRNAs in comparison to plants infected with PVY-O and PVY-N. In PVY-infected plants, the 21 nt class was predominant whereas in healthy potato plants 24 nt class had the maximum population. VsiRNAs were derived from every nucleotide position of the PVY genome and certain hotspots were identified which produced relatively more vsiRNAs. Additionally, six novel microRNAs were found in PVY-infected plants. Potato virus S (PVS; Carlavirus: Betaflexiviridae) is another important potato virus distributed worldwide. The outcome of mixed infection of PVS and PVY was studied under controlled conditions in three potato cultivars, Defender, Desiree and Russet Burbank. Results showed that PVS has an antagonistic effect on PVY replication in mixed infection. The antagonistic effect was associated with less severe symptoms in dual infections as well as reduced PVY multiplication. Symptoms of PVS were not visible in Desiree and Russet Burbank plants except Defender which showed bronzing spots on the leaves. PVY symptoms included mosaic, mottling and leaf drop. It was found that the antagonistic effect of PVS on the replication of PVY is independent of host genetic background as the same pattern was found in all three potato cultivars. Potato cultivars such as Desiree carrying the Ny gene show HR to infection with the ordinary strain of PVY. In comparison to Russet Burbank, PVY levels in Desiree decreased with increasing number of days post-inoculation. The HR was found to be specific to PVY-O and was not elicited by infection by PVY-N or PVY-NTN.
Von der Nische in den Mainstream
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: subject: Nachhaltigkeit
subject: Diffusion
subject: Zivilgesellschaft
subject: Sozialer Wandel
subject: Soziale Aspekte
subject: Initiativen
subject: Gesellschaftliche Transformation
subject: Nachhaltigkeit | Strategien | Internationales
subject: Sustainability | Strategies | International matters

description: Gute Beispiele nachhaltigen Handelns haben eine wichtige Funktion für den Wandel hin zu einer nachhaltigen Gesellschaft, weil sie Vorbild und Anregung für Menschen und Institutionen sind. Sie agieren, ohne auf bessere Rahmenbedingungen zu warten, und zeigen, dassNachhaltigkeittrotz aller Zwänge des Alltags und des Marktes möglich ist. Doch wie können gute Beispiele nachhaltigen Handelns zum Mainstream gemacht werden? Und wie kann (Umwelt-)Politik dies unterstützen? Im Rahmen dieser Konzeptstudie wurde dieses Forschungsfeld systematisch für die Ressortforschung erschlossen. Die Konzeptstudie gliederte sich entlang folgender Forschungsfragen:
 Was sind "gute" Beispiele für nachhaltiges Handeln?
 Wie könnte eine Ordnungsstruktur aussehen, um die gesamte Bandbreite für nachhaltiger Verhaltensweisen und Praktiken zu erfassen?
 Wie verbreiten sich bestimmte Verhaltensweisen und Praktiken in der Gesellschaft?
 Welche Motive und persönlichen Voraussetzungen müssen vorhanden sein, um Nachhaltiges Handeln zu beginnen (oder gar eine Nachhaltigkeitsinitiative zu starten) und Nachhaltiges Handeln dauerhaft beizubehalten.
Quelle: www.umweltbundesamt.de

description: Gute Beispiele nachhaltigen Handelns haben eine wichtige Funktion für den Wandel hin zu einer nachhaltigen Gesellschaft, weil sie Vorbild und Anregung für Menschen und Institutionen sind. Sie agieren, ohne auf bessere Rahmenbedingungen zu warten, und zeigen, dass ⁠Nachhaltigkeit⁠ trotz aller Zwänge des Alltags und des Marktes möglich ist. Doch wie können gute Beispiele nachhaltigen Handelns zum Mainstream gemacht werden? Und wie kann (Umwelt-)Politik dies unterstützen? Im Rahmen dieser Konzeptstudie wurde dieses Forschungsfeld systematisch für die Ressortforschung erschlossen. Die Konzeptstudie gliederte sich entlang folgender Forschungsfragen:Was sind „gute“ Beispiele für nachhaltiges Handeln?Wie könnte eine Ordnungsstruktur aussehen, um die gesamte Bandbreite für nachhaltiger Verhaltensweisen und Praktiken zu erfassen?Wie verbreiten sich bestimmte Verhaltensweisen und Praktiken in der Gesellschaft?Welche Motive und persönlichen Voraussetzungen müssen vorhanden sein, um Nachhaltiges Handeln zu beginnen (oder gar eine Nachhaltigkeitsinitiative zu starten) und Nachhaltiges Handeln dauerhaft beizubehalten.
Risks characteristic to Agile project management methodologies and responses to them
Creators: name: WALCZAK, Wojciech
name: KUCHTA, Dorota
Publisher: name: Wrocław University of Technology, Wrocław University of Economics, Polish Operational and Systems Research Society
Year: 2013
Subjects: risk, risk management, agile software development, agile project management

description: OPERATIONS RESEARCH AND DECISIONS; ISSN 2081-8858
LINE-1 retrotransposon-mediated DNA transductions in endometriosis associated 1 ovarian cancers
Creators: name: Xia, Zhouchunyang
name: Cochrane, Dawn Renee
name: Anglesio, Michael
name: Wang, Yi Kan
name: Nazeran, Tayyebeh
name: Tessier-Cloutier, Basile
name: McConechy, Melissa K.
name: Senz, Janine
name: Lum, Amy
name: Bashashati, Ali
name: Shah, Sohrab P.
name: Huntsman, David G.
Publisher: name: Elsevier
Year: 2018

description: Objective: Endometrioid (ENOC) and clear cell ovarian carcinoma (CCOC) share a common precursor lesion, endometriosis, hence the designation endometriosis associated ovarian cancers (EAOC). Long interspersed nuclear element 1 (LINE-1 or L1), is a family of mobile genetic elements activated in many cancers capable of moving neighboring DNA through 3’ transductions. Here we investigated the involvement of specific L1-mediated transductions in EAOCs. Methods: Through whole genome sequencing, we identified active L1-mediated transductions originating within the TTC28 gene in 34% (10/29) of ENOC and 31% (11/35) of CCOC cases. We used PCR and capillary sequencing to assess the presence of specific TTC28-L1 transductions in formalin-fixed paraffin-embedded (FFPE) blocks from six different anatomical sites (five tumors and one normal control) for four ENOC and three CCOC cases, and compared the results to the presence of single nucleotide variations (SNVs)/frame shift (fs) mutations detected using multiplex PCR and next generation sequencing. Results: TTC28-L1 mediated transductions were identified in at least three tumor samplings in all cases, and were present in all five tumor samplings in 5/7 (71%) cases. In these cases, KRAS, PIK3CA, CTNNB1, ARID1A, and PTEN mutations were found across all tumor sites whilst other selected SNV/fs mutations of unknown significance were present at varying allelic frequencies. Conclusion: The TTC28-L1 transductions along with classical driver mutations were near ubiquitous across the tumors, suggesting that L1 activation likely occurred early in the development of EAOCs. TTC28-L1 transductions could potentially be used to determine clonal relationships and to track ovarian cancer progression.
title: Checklisten für die Untersuchung und Beurteilung des Zustandes von Anlagen mit wassergefährdenden Stoffen und Zubereitungen
title: Anlagenbezogener Gewässerschutz: Checkliste 17: Raffinerien - 2
titleType: AlternativeTitle
Creators: name: Winkelmann-Oei, Gerhard
name: Platkowski, Jörg
Publisher: name: My University
Year: 2016
Subjects: subject: Gewässerschutz
subject: Risikomanagement
subject: Leitfaden
subject: anlagenbezogen
subject: Wasserverschmutzung
subject: Wasserschadstoffe
subject: Checkliste
subject: Chemikalien
subject: Chemicals

description: Basierend auf den Empfehlungen der internationalen Flussgebiets- und Gewässerkommissionen wurde ein Checklisten-Konzept entwickelt, welches eine effiziente Beurteilung des Zustandes von Anlagen mit wassergefährdenden Stoffen und Zubereitungen ermöglicht. Es enthält eine Übersicht  über potentielle Handlungsfelder sowie spezielle Checklisten, welche nach Funktionseinheiten, Branchen und Risikobereichen aufgeteilt sind.
ОПИСАНИЕ  ИНФОРМАЦИОННО-КОММУНИКАЦИОННЫХ ТЕХНОЛОГИЙ  И ОТБОР МАТЕРИАЛОВ ДЛЯ ИХ ОБУЧЕНИЯ НА ЗАНЯТИЯХ РУССКОГО ЯЗЫКА В ВУЗЕ.
Creators: name: Очилдиева, Хилолахон
name: Гуламова, Мехриноз
name: Валижонова, Фарангиз
Publisher: name: Zenodo
Year: 2024

description:  В данной статье  рассматриваются   теоретические проблемы  использования информационно-коммуникационных технологий на занятиях русского языка и литературы в целях развития русской речи учащейся молодёжи. Кроме того в статье представлены теоретические основы применения средств новых информационно-коммуникативных  технологий в вузовском учебном процессе.
The syntax of adverbs in English.
Creators: name: Manga, Louise.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Language, Linguistics.

description: In this thesis I use the Principles and Parameters model of generative grammar to explain the surface distribution of adverbs in English. Using the current parameters and principals assumed for UG plus the rule of move $\alpha,$ I explain the distribution of both sentential and VP-adverbs. I propose that adverbs are predicates subcategorizing for their arguments at D-S. Like other predicates in English, adverbs are generated on the right of their subjects. Certain adverbs subcategorize for two arguments while other adverbs subcategorize for one argument. The selectional restrictions of the adverb are satisfied at S-S. Like other predicates, it is the maximal projection (AdvP) that governs its subject(s). Government is an m-command relationship. The AdvP can move to the left, either through substitution to an empty X$\sp\prime$ adjunction site or through adjunction to an XP. The maximal projection of the subject forms a barrier out of which the AdvP can not move. Maximal projections, except AgrP, are barriers. In English, the AdvP can not move if the adverb is subcategorized for by the verb. This thesis also compares the explanatory powers of my approach to recent syntactic approaches by Iatridou, Travis and Zagona. I also relate my findings to the semantic approaches by Jackendoff, Bellert and Rochette.
The use of pretherapy training to enhance group cognitive therapy for depressed elderly persons.
Creators: name: Latour, David.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Psychology, Clinical.

description: This study was devised to determine the effectiveness of a theoretically-based pretherapy training procedure in enhancing group cognitive therapy for depressed older adults. Twenty-nine subjects were randomly assigned to a pretherapy training condition or an attention-placebo control condition. All subjects were 65 years of age or older, had a score of 14 or higher on the Beck Depression Inventory or 14 or more on the Geriatric Depression Scale, and had no previous experience in psychotherapy or special knowledge of the psychotherapeutic process. Subjects in both conditions received four sessions in the pretherapy phase, followed by 12 sessions in the therapy phase. The pretherapy training procedure was based on Bandura's social cognitive theory and included verbal persuasion (written and verbal material), vicarious experience (videotape), and performance accomplishment (structured group exercises). Four categories of dependent variables were examined: attendance and dropout rates, immediate effects of pretherapy training (i.e., knowledge about therapy and role expectations), observer ratings of in-therapy client behavior, and outcome as measured by subject and observer ratings of improvement throughout therapy. The results revealed no significant differences between conditions on attendance and dropout rates. Subjects in the pretherapy training condition had significantly greater knowledge of psychotherapy at the end of the pretherapy phase than subjects in the attention-placebo condition. The analysis of subject role expectancies in the pretherapy phase revealed that subjects in the pretherapy training condition exhibited significantly less audience-seeking expectancies than subjects in the attention-placebo condition. The process measure revealed that subjects in the pretherapy training condition made more statements related to the problems they were experiencing than subjects in the attention-placebo condition. There were no significant differences between conditions with respect to outcome. For the two conditions taken together, 53.7% of the subjects exhibited clinically significant improvement by the end of therapy. The results were discussed in terms of the appropriateness of measuring role expectancies, and suggestions were made for measuring other expectancies, based on social cognitive theory. The clinical implications of the findings as well as the feasibility of in vivo use of pretherapy training procedures were also discussed. (Abstract shortened by UMI.)
La protection de la création vestimentaire : étude d'une application problématique des droits intellectuels.
Creators: name: Bisson, Grégoire.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1991
Subjects: subject: Law.

description: Une premiere partie etudie en quoi la nouveaute d'un vetement, qu'elle participe de l'invention ou tienne a la presentation, peut ainsi e tre protegee. Une analyse des regimes canadiens des brevets et des dessins industriels, premier et second moyens de protection envisages, met en evidence le caractere ineluctable de la fonction en matiere de creation vestimentaire; en consequence, ces regimes ne sont que rarement applicables et ne benefecient en outre qu'aux details, l'apparence d'ensemble pouvant etre impunement imitee ou, du moins, approchee. Recherchant dans une seconde partie a quel titre l'ensemble peut donc etre protege, la these mene en un premier temps a la constatation que la protection en vertu du droit d'auteur, a priori concevable, se heurte a des obstacles d'ordre technique, propres au regime canadien. Toutefois, une incursion dans le droit francais permet finalement de conclure que meme une legislation specifique visant l'originalite, quatrieme moyen envisage, serait impuissante a proteger l'ensemble autrement qu'a l'encontre des seules copies serviles, en raison toujours de l'incontournable predominance de la fonction. (Abstract shortened by UMI.)
Semi-analytic models for the CANDELS survey: Comparison of predictions for intrinsic galaxy properties
Creators: name: Lu, Yu
name: Wechsler, Risa H.
name: Somerville, Rachel S.
name: Croton, Darren
name: Porter, Lauren
name: Primack, Joel
name: Behroozi, Peter S.
name: Ferguson, Henry C.
name: Koo, David C.
name: Guo, Yicheng
name: Safarzadeh, Mohammadtaher
name: Finlator, Kristian
name: Castellano, Marco
name: White, Catherine E.
name: Sommariva, Veronica
name: Moody, Chris
Publisher: name: Swinburne
Year: 2024

description: We compare the predictions of three independently developed semi-analytic galaxy formation models (SAMs) that are being used to aid in the interpretation of results from the CANDELS survey. These models are each applied to the same set of halo merger trees extracted from the 'Bolshoi' high-resolution cosmological N-body simulation and are carefully tuned to match the local galaxy stellar mass function using the powerful method of Bayesian Inference coupled with Markov Chain Monte Carlo or by hand. The comparisons reveal that in spite of the significantly different parameterizations for star formation and feedback processes, the three models yield qualitatively similar predictions for the assembly histories of galaxy stellar mass and star formation over cosmic time. Comparing SAM predictions with existing estimates of the stellar mass function from z = 0-8, we show that the SAMs generally require strong outflows to suppress star formation in low-mass halos to match the present-day stellar mass function, as is the present common wisdom. However, all of the models considered produce predictions for the star formation rates (SFRs) and metallicities of low-mass galaxies that are inconsistent with existing data. The predictions for metallicity-stellar mass relations and their evolution clearly diverge between the models. We suggest that large differences in the metallicity relations and small differences in the stellar mass assembly histories of model galaxies stem from different assumptions for the outflow mass-loading factor produced by feedback. Importantly, while more accurate observational measurements for stellar mass, SFR and metallicity of galaxies at 1 < z < 5 will discriminate between models, the discrepancies between the constrained models and existing data of these observables have already revealed challenging problems in understanding star formation and its feedback in galaxy formation. The three sets of models are being used to construct catalogs of mock galaxies on light cones that have the same geometry as the CANDELS survey, which should be particularly useful for quantifying the biases and uncertainties on measurements and inferences from the real observations.
Acute Respiratory Distress Syndrome: Incidence, Pathophysiology and Selected Interventions
Creators: name: Miller, Benjamin J.
Publisher: name: Washington State University
Year: 2000

description: Acute respiratory distress syndrome (ARDS) is a clinical response to a primary or secondary pulmonary injury or insult that is associated with severe hypoxemia. The incidence of ARDS has been reported between 1.5 and 75 cases per 100,000 population per year with mortality rates reaching 45-64 %. ARDS is severe hypoxia with a Pa02/Fi02 < 200 torr from a non-cardiogenic pulmonary edema. ARDS is an end result of the Systemic Inflammatory Response Syndrome (SIRS), with a thick exudative fluid collecting in the pulmonary interstitium preventing the diffusion of oxygen across the alveolar-capillary membrane. Mechanical ventilation, supplemental oxygen and positive end expiratory pressure (PEEP) are the hallmark therapies of supportive care. The management goal for ARDS is to provide maximal oxygenation while decreasing iatrogenic complications of mechanical ventilation. Two interventions: the prone position and low tidal volume ventilation have been shown to improve oxygenation and mortality rates respectively for patients with ARDS.
P11 promoter methylation predicts the antidepressant effect of electroconvulsive therapy
Creators: name: Neyazi, Alexandra
name: Theilmann, Wiebke
name: Brandt, Claudia
name: Rantamäki, Tomi
name: Matsui, Nobuaki
name: Rhein, Mathias
name: Kornhuber, Johannes
name: Bajbouj, Malek
name: Sperling, Wolfgang
name: Bleich, Stefan
name: Frieling, Helge
name: Löscher, Wolfgang
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: Biomarkers
subject: Neuroscience
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Although electroconvulsive therapy (ECT) is among the most effective treatment options for pharmacoresistant major depressive disorder (MDD), some patients still remain refractory to standard ECT practise. Thus, there is a need for markers reliably predicting ECT non/response. In our study, we have taken a novel translational approach for discovering potential biomarkers for the prediction of ECT response. Our hypothesis was that the promoter methylation of p11, a multifunctional protein involved in both depressive-like states and antidepressant treatment responses, is differently regulated in ECT responders vs. nonresponders and thus be a putative biomarker of ECT response. The chronic mild stress model of MDD was adapted with the aim to obtain rats that are resistant to conventional antidepressant drugs (citalopram). Subsequently, electroconvulsive stimulation (ECS) was used to select responders and nonresponders, and compare p11 expression and promoter methylation. In the rat experiments we found that the gene promoter methylation and expression of p11 significantly correlate with the antidepressant effect of ECS. Next, we investigated the predictive properties of p11 promoter methylation in two clinical cohorts of patients with pharmacoresistant MDD. In a proof-of-concept clinical trial in 11 patients with refractory MDD, higher p11 promoter methylation was found in responders to ECT. This finding was replicated in an independent sample of 65 patients with pharmacoresistant MDD. This translational study successfully validated the first biomarker reliably predicting the responsiveness to ECT. Prescreening of this biomarker could help to identify patients eligible for first-line ECT treatment and also help to develop novel antidepressant treatment procedures for depressed patients resistant to all currently approved antidepressant treatments.
title: Male Lineages in Brazil
title: Intercontinental Admixture and Stratification of the European Background
titleType: Subtitle
Creators: name: Resque, Rafael
name: Gusmão, Leonor
name: Geppert, Maria
name: Roewer, Lutz
name: Palha, Teresinha
name: Alvarez, Luis
name: Ribeiro-Dos-Santos, Ândrea
name: Santos, Sidney
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: The non-recombining nature of the Y chromosome and the well-established phylogeny of Y-specific Single Nucleotide Polymorphisms (Y-SNPs) make them useful for defining haplogroups with high geographical specificity; therefore, they are more apt than the Y-STRs to detect population stratification in admixed populations from diverse continental origins. Different Y-SNP typing strategies have been described to address issues of population history and movements within geographic territories of interest. In this study, we investigated a set of 41 Y-SNPs in 1217 unrelated males from the five Brazilian geopolitical regions, aiming to disclose the genetic structure of male lineages in the country. A population comparison based on pairwise FST genetic distances did not reveal statistically significant differences in haplogroup frequency distributions among populations from the different regions. The genetic differences observed among regions were, however, consistent with the colonization history of the country. The sample from the Northern region presented the highest Native American ancestry (8.4%), whereas the more pronounced African contribution could be observed in the Northeastern population (15.1%). The Central-Western and Southern samples showed the higher European contributions (95.7% and 93.6%, respectively). The Southeastern region presented significant European (86.1%) and African (12.0%) contributions. The subtyping of the most frequent European lineage in Brazil (R1b1a-M269) allowed differences in the genetic European background of the five Brazilian regions to be investigated for the first time.
Studies on the histochemical nature of the colloid of the thyroid gland of the male albino rat.
Creators: name: LaHam, Quentin N.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1959
Subjects: subject: Biology, Animal Physiology.

description: A new staining technique has been developed for the thyroid gland of the rat which in addition to being an excellent histological stain is a histochemical method for the rapid identification of the colloid containing iodinated thyroglobulin from that which contains biologically inactive protein material. Various indices such as incorporation of radioiodine 131, gland weight, epithelial height, and total number of follicles have been used totest the validity of the color reaction in the colloid. The comparison of these diverse indices of thyroid activity show that the blue colloid is directly related to the physical activity of the gland. As a result of our studies further insight has been gained into several aspects of thyroid physiology: (a) in the normal rat only about fifty percent of the gland contains active colloidal material; (b) complete incorporation of iodine 131 into the colloid requires longer than twenty-four hours in the normal rat; (c) information on the role of thiouracil raises the question of its action in iodine deficient rats; (d) evidence is offered for intracellular protein binding of iodine rather than the view that it is restricted to the follicular colloid; (e) additional evidence is presented that short exposure to cold brings about an immediate physiological and morphological response by the thyroid; (f) ascorbic acid has no apparent effect on the thyroid itself; (g) evidence favors the view that the pituitary gland is the rate-controlling principle in thyriod hormonogenesis; (h) the histochemical method may be of value in pathological diagnosis of thyriod slices and biopsies.
The effects of selected exercise intensities on skeletal muscle protein degradation.
Creators: name: McNeely, Edward.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Biology, Animal Physiology.

description: The purpose of this study was to examine the effects of selected exercise intensities on muscle protein degradation. On two occasions eight male trained subjects performed a bench press exercise: on one occasion each set consisted of 10 repetitions at 70% of 1RM; on the other occasion each set consisted of 5 repetitions at 85% of 1RM. Venous blood samples were drawn preceding, immediately following and 24 hours after each exercise sessions and analyzed for 3-methylhistidine and tyrosine. The results showed a significant decrease in the concentration of 3-methyhistidine immediately following exercise. There was a significant decrease in tyrosine following exercise at 85% 1RM when compared to baseline. There was not a significant difference found between the 70 and 85% of 1RM protocols for either 3-methylhistidine or tyrosine. The lack of difference between 70 and 85% of 1RM may have been due to similar motor unit recruitment patterns for the two intensities. The exact mechanisms responsible for decreased protein degradation following strength training exercise are presently unclear but may be the result of mechanical tension placed on the muscle fibre.
3320952.pdf
Creators: name: Wang, Yi
name: Chen, Siming
name: Yu, Ying
name: Zhou, Lidan
name: Liu, Lin
name: CHUAN, YANG
name: liao, Mengya
name: Tang, Mingchu
name: Liu, Zizhuo
name: Wu, Jiang
Publisher: name: Optica Publishing Group
Year: 2018
Subjects: Uncategorized

description: Supplemental Document
Statistical characterization of streamflow persistence
Creators: name: Tofighi, Soheyla
Publisher: name: University of Iowa
Year: 2025
Subjects: public abstract

description: Temporal and spatial persistence of streamflow can serve as a reference method for other forecasting approaches, including physics- and data-based models. The evolution of persistence-based forecasts errors in both space and time is examined here through parametric and non-parametric statistical descriptions. The dynamics of streamflow which integrates rainfall conversion to runoff and its transport within basin boundaries is strongly dependent on basin scale along with many other factors. The spatial scale of the basins considered in this study ranges from about 10 to 20,000 km2 for a well-drained landscape of Iowa in the central United States. In analyzing persistence as a forecasting method, a range of lead-times from 1-240 hours (ten days) is considered. 15-min resolution streamflow observations from 2013 to 2022 at 140 U.S. Geological Survey (USGS) streamflow gauges monitoring streams and rivers throughout Iowa are used in the current study. The analyses demonstrate that the Johnson-SU distribution is the best fit to the persistence-based forecast errors. In pure temporal persistence forecasts, it is found that the median of errors is almost zero, independent of basin size, and the inter quartile range (IQR) of errors is the direct function of the basin size. In spatial persistence, forecasts are evaluated at a gauge downstream, and the ratio of the respective drainage areas is termed monitored area fraction (MAR). For spatial persistence, the median of errors has the positive correlation with MAR, and IQR of errors has the inverse relationship with that. This thesis also proposes an AI-based model for streamflow forecasting. This model’s performance is evaluated against persistence-based forecasts. The findings of this study can be used in assessment of operational forecasting systems.
Analyse évaluative des objectifs d'apprentissage de sessions de formation pré-départ pour conseillers techniques oeuvrant en coopération internationale : le cas de l'ACDI.
Creators: name: Champagne, André.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Education, Bilingual and Multicultural.

description: Dans le domaine de la formation interculturelle pour des personnes qui vont vivre et travailler dans une autre culture, il y a des questionnements sur la veritable nature des formations. Sont-elles des sessions de preparation et d'orientation fournissant de l'information sur le pays et la culture hotes, ou sont-elles des sessions de formation developpant des habiletes et des capacites d'interagir efficacement avec les individus de l'autre culture? Cette recherche descriptive, de nature evaluative, utilisant une approche d'analyse documentaire, analyse les objectifs d'apprentissage de sessions de formation pour conseillers techniques canadiens avant leur affectation outre-mer dans le cadre de projet de cooperation internationale. Partant de la notion de l'efficacite interculturelle, des qualites requises d'un conseiller technique efficace et du continuum du developpement de la sensibilite culturelle de Milton Bennett, un outil d'analyse est developpe. La demarche comprend un survol du developpement international ainsi que certaines perspectives des efforts de cooperation internationale d'agences et d'organismes impliques dans ce milieu. Un des moyens privilegie de la cooperation internationale, la cooperation technique est decrite et un bilan, tire de la litterature, est degage. La notion de l'efficacite interculturelle et les qualites requises d'un conseiller technique efficace interculturellement sont exposees et un continuum de sensibilite culturelle est explique. Une grille est developpee afin de pouvoir analyser les objectifs d'apprentissage de sessions de formation interculturelle. Une correlation, decoulant de l'analyse des objectifs d'apprentissage, est faite entre l'efficacite interculturelle, le developpement de la sensibilite culturelle et la formation interculturelle.
Anti-Stress Effects of Lemon Balm-Containing Foods
Creators: name: Scholey, Andrew
name: Gibbs, Amy
name: Neale, Chris
name: Perry, Naomi
name: Ossoukhova, Anastasia
name: Bilog, Vanessa
name: Kras, Marni
name: Scholz, Claudia
name: Sass, Mathias
name: Buchwald-Werner, Sybille
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 520201
subject: Behavioural genetics
classificationCode: 520202
subject: Behavioural neuroscience
classificationCode: 520203
subject: Cognitive neuroscience
classificationCode: 520205
subject: Psychopharmacology
classificationCode: 520206
subject: Psychophysiology
classificationCode: 520207
subject: Social and affective neuroscience
classificationCode: 520301
subject: Clinical neuropsychology
classificationCode: 520401
subject: Cognition
classificationCode: 520403
subject: Learning, motivation and emotion

description: Lemon balm (Melissa officinalis) has been used historically and contemporarily as a modulator of mood and cognitive function, with anxiolytic effects following administration of capsules, coated tablets and topical application. Following a pilot study with lemon balm extract administered as a water based drink, which confirmed absorption of rosmarinic acid effects on mood and cognitive function, we conducted two similar double-blind, placebo-controlled, crossover studies. These evaluated the mood and cognitive effects of a standardised M. officinalis preparation administered in palatable forms in a beverage and in yoghurt. In each study a cohort of healthy young adults' self-rated aspects of mood were measured before and after a multi-tasking framework (MTF) administered one hour and three hours following one of four treatments. Both active lemon balm treatments were generally associated with improvements in mood and/or cognitive performance, though there were some behavioral 'costs' at other doses and these effects depended to some degree on the delivery matrix.
Talking 'costs': Seniors, cell phones and the personal and political economy of telecommunications in Canada
Creators: name: Sawchuk, Kim
name: Crow, Barbara
Publisher: name: Swinburne
Year: 2024

description: Seniors, defined as persons aged 65 and up, are becoming a much larger demographic in Canada at the same time as the wireless telecommunications industry is expanding. Yet in terms of academic research, few studies have examined how seniors understand and negotiate the influx of digital communications devices, such as the cellular telephone, into their world. Using industry and government data, as well as individual and group interviews and observations with over 120 Canadian seniors, this paper examines the repertoire of 'cost' in the group discussions held with this cohort. It does so from the perspective of a feminist political economy that takes into account individual experiences in the context of macro-level, structural analyses of institutions and industry. This preliminary study suggests that financial considerations play a significant role in seniors' cell phone practices and may lead to a strategic decision to impose restrictions on their use. These restrictions to access often run counter to the desire, amongst many seniors, to have access to a cell phone for 'emergency purposes'. The comments made by this cohort make apparent the way that personal economies within a household on restricted or fixed incomes intersect with the practices of the wireless industry and suggest future avenues for media and ageing studies.
Vitamin D and Depressive Symptoms in Women During the Winter: A Pilot Study
Creators: name: Shipowick, Clarissa
Publisher: name: Washington State University
Year: 2007

description: Background: More than half of all women do not meet daily vitamin D nutrient intake recommendations, and research indicates that vitamin D supplementation during the winter may decrease depressive symptoms.\nObjectives: To examine the relationship of vitamin D supplementation and depressive symptoms in women living in a northern climate during the winter months. Method: In a quasi-experimental pilot study, nine women with serum vitamin D levels (as measured by 25 OR vitamin D) below 40 nanograms/milliliter (ng/mL) were administered the Beck Depression Inventory II (BDI-II). After eight weeks of vitamin D3 supplementation, six of these women completed the BDI-II and had their serum 25 OR vitamin D levels re-assessed. Results: The baseline and follow-up mean 25 OR vitamin D levels for the sub sample of six women were 21.8 ng/mL (SD = 8.33, range = 14-37) and 48.2 (SD=20.01, range 29-84) respectively (t = -4.11, p = .009). The baseline and follow-up mean BDI-II scores were 31.8 (SD = 4.79, range = 26-40) and 21.2 (SD = 11.07, range = 8-37) respectively (t = 3.37, p = .02). Vitamin D supplementation was associated with an increase in the serum D levels by an average of about 27 ng/mL, and was associated with a decline (demonstrating a negative correlation) in the BDI-II scores of an average of about 10 points. Vitamin D levels above 40 ng/mL at the end of the study were associated with BDI-II scores of 14 or less, a level indicative of minimal depressive symptoms.\nDiscussion: This pilot study suggests that supplenlental vitamin D3 improves serum 25 OR vitamin D levels and reduces depressive symptoms. Adequately powered clinical trials are needed to better evaluate these relationships.
Studies on a continuous Markov model for probabilistic fault analysis in VLSI sequential circuits using computer simulation.
Creators: name: Wong, Kam Lung.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Engineering, Electronics and Electrical.

description: A continuous parameter Markov model is proposed in this thesis to detect permanent stuck-at faults in sequential circuits by random testing. Given a sequential circuits with certain stuck-at faults specified, the fault-free and the faulty state tables of the circuit can be readily derived. By simulation of these two state tables on a computer, the parameters of the desired Markov model can be obtained. For a specified confidence level, it is easy to derive the model parameters and to estimate the required testing time. A complete mathematical analysis of the model is given that provides some useful insights into the nature of faults in relation to random testing and the associated confidence level.
title: Climate change and health
title: Climate change and health
titleType: AlternativeTitle
Creators: name: Mücke, Hans-Guido
name: Matzarakis, Andreas
Publisher: name: Umweltbundesamt
Year: 2020
Subjects: subject: Hitzewelle
subject: Gesundheit
subject: heat wave
subject: hot weather
subject: health
subject: Climate | Energy
subject: Health

description: Long-lasting periods of extreme heat - so-called heat waves - have been occurring in unusual frequency in Europe and Germany for about 30 years. The resulting health problems can be considerable, sometimes life-threatening. The summer 2018 was the second hottest since climate records started in 1881. The hottest ever summer was in 2003, which claimed over 40,000 lives in several countries in Western Europe (around 7,000 in Germany). The increased heat-related mortality primarily affects older people. The guide provides important information for a well adapted and individual protective behaviour for summer heat. Source: www.umweltbundesamt.de
description: Long-lasting periods of extreme heat - so-called heat waves - have been occurring in unusual frequency in Europe and Germany for about 30 years. The resulting health problems can be considerable, sometimes life-threatening. The summer 2018 was the second hottest since climate records started in 1881. The hottest ever summer was in 2003, which claimed over 40,000 lives in several countries in Western Europe (around 7,000 in Germany). The increased heat-related mortality primarily affects older people. The guide provides important information for a well adapted and individual protective behaviour for summer heat.
Keck/MOSFIRE spectroscopic confirmation of a virgo-like cluster ancestor at z = 2.095
Creators: name: Yuan, Tiantian
name: Nanayakkara, Themiya
name: Kacprzak, Glenn
name: Tran, Kim-Vy H.
name: Glazebrook, Karl
name: Kewley, Lisa J.
name: Spitler, Lee R.
name: Poole, Gregory B.
name: Labbe, Ivo
name: Straatman, Caroline M. S.
name: Tomczak, Adam R.
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: We present spectroscopic confirmation of a galaxy cluster at z = 2.095 in the COSMOS field. This galaxy cluster was first reported in the ZFOURGE survey as harboring evolved massive galaxies using photometric redshifts derived with deep near-infrared (NIR) medium-band filters. We obtain medium-resolution (R ~ 3600) NIR spectroscopy with MOSFIRE on the Keck 1 telescope and secure 180 redshifts in a 12' × 12' region. We find a prominent spike of 57 galaxies at z = 2.095 corresponding to the galaxy cluster. The cluster velocity dispersion is measured to be σv1D = 552 ± 52 km s-1. This is the first study of a galaxy cluster in this redshift range (z gsim 2.0) with the combination of spectral resolution (~26 km s-1) and the number of confirmed members (>50) needed to impose a meaningful constraint on the cluster velocity dispersion and map its members over a large field of view. Our ΛCDM cosmological simulation suggests that this cluster will most likely evolve into a Virgo-like cluster with M vir = 1014.4 ± 0.3 M ☉ (68% confidence) at z ~ 0. The theoretical probability of finding such a cluster is ~4%. Our results demonstrate the feasibility of studying galaxy clusters at z > 2 in the same detailed manner using multi-object NIR spectrographs as has been done in the optical in lower-redshift clusters.
Ten years of CAZypedia : A living encyclopedia of carbohydrate-active enzymes
Creators: name: Consortium, The CAZypedia
Publisher: name: The University of British Columbia
Year: 2018

description: CAZypedia was initiated in 2007 to create a comprehensive, living encyclopedia of the carbohydrate-active enzymes (CAZymes) and associated carbohydrate-binding modules involved in the synthesis, modification, and degradation of complex carbohydrates. CAZypedia is closely connected with the actively-curated CAZy database, which provides a sequence-based foundation for the biochemical, mechanistic, and structural characterization of these diverse proteins. Now celebrating its 10th anniversary online, CAZypedia is a successful example of dynamic, community-driven, and expert-based biocuration. CAZypedia is an open-access resource available at URL http://www.cazypedia.org.
Spurensuche mit Luftikus
Creators: name: Böger, Britta
Publisher: name: My University
Year: 2016
Subjects: subject: Umwelterziehung
subject: Luftreinhaltung
subject: Luftverunreinigung
subject: Kinderbuch
subject: Umweltbildung
subject: Luftverschmutzung
subject: Luft

description: Luft kann man nicht sehen und nicht anfassen und doch ist sie für uns lebenswichtig. Was ist eigentlich Luft? Leo und Polly Pop begeben sich auf eine spannende Spurensuche. In diesem Kinderbuch zum Lesen und Mitmachen geht es zum Beispiel darum, wodurch Luft verschmutzt wird, was das für Gesundheit und Klima bedeutet und was man dazu beitragen kann, die Luft sauber zu halten. Quelle: https://www.umweltbundesamt.de
description: Luft kann man nicht sehen und nicht anfassen und doch ist sie für uns lebenswichtig. Was ist eigentlich Luft? Leo und Polly Pop begeben sich auf eine spannende Spurensuche. In diesem Kinderbuch zum Lesen und Mitmachen geht es zum Beispiel darum, wodurch Luft verschmutzt wird, was das für Gesundheit und ⁠Klima⁠ bedeutet und was man dazu beitragen kann, die Luft sauber zu halten.
Graduating undergraduate student Internet use: How tech-savvy is the Net Generation?
Creators: name: Freeman, Wendy
Publisher: name: Swinburne
Year: 2024

description: This study contributes to a growing body of research that calls into question the assumption that all members of the Net Generation are uniformly sophisticated in their use of web-based technologies. Students graduating from an undergraduate business program were surveyed about their use of a range of technologies for academic and personal uses. Findings suggest that the majority of respondents use a limited range of technologies everyday to communicate and to stream audio and video web content. Many fewer students regularly used technologies associated with producing web content. Differences were also found in technology use patterns across gender lines.
Two birds with one stone - fast and simultaneous analysis of microplastics
Creators: name: Eisentraut, Paul
name: Dümichen, Erik
name: Ruhl, Aki Sebastian
Publisher: name: My University
Year: 2018
Subjects: Gaschromatografie
Massenspektrometrie

description: Analysis of microplastic particles in environmental samples needs sophisticated techniques and is time intensive due to sample preparation and detection. Alternatives to the most common (micro-) spectroscopic techniques, Fourier transform infrared and Raman spectroscopy, are thermoanalytical methods, in which specific decomposition products can be analyzed as marker compounds for different kinds of plastic types and mass contents. Thermal extraction desorption gas chromatography-mass spectrometry allows the fast identification and quantification of MP in environmental samples without sample preparation. Whereas to date only the analysis of thermoplastic polymers has been realized, this is the first time that even the analysis of tire wear (TW) content in environmental samples has been possible. Various marker compounds for TW were identified. They include characteristic decomposition products of elastomers, antioxidants, and vulcanization agents. Advantages and drawbacks of these marker substances were evaluated. Environmental samples from street runoff were exemplarily investigated, and the results are presented. © 2018 American Chemical Society.