cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Impact of placental transporters and offspring sex on cadmium toxicity
Creators: name: Kozlosky, Danielle Lynne
Publisher: name: No Publisher Supplied
Year: 2023

description: Across the globe, up to 98% of pregnancies have measurable levels of the environmental toxicant cadmium (Cd). Following gestational exposures, Cd accumulates in the placenta where it induces toxicity and affects male and female offspring differently through mechanisms that are currently unknown. The placenta restricts the transfer of toxicants by expressing efflux transporters, including the breast cancer resistance protein (human BCRP/ABCG2, mouse Bcrp/Abcg2). Published work from our laboratory and collaborators showed that BCRP/Bcrp provides protection against Cd accumulation and toxicity in cells, mice, and humans. The purpose of this dissertation was to investigate the effects of Cd on the placenta and the ability of the BCRP/Bcrp transporter to protect against fetoplacental toxicity. Following administration of 5 mg/kg CdCl2 on gestational day (GD) 9 to C57BL/6Crl mice, reduced growth was observed in male fetuses on GD18, with minimal changes in females. Further examinations revealed the disruption of vasculature development and reduced expression of glucose transporters in male placentas that provide potential mechanisms underlying their reduced fetal growth despite the greater accumulation of Cd in female placentas. Subsequent studies demonstrated that the absence of Bcrp expression increased placental Cd concentrations, and altered placental vasculature development and nutrient transporter enrichment, leading to restricted growth of Bcrp-null offspring. Final studies capitalized on the United States-based UPSIDE pregnancy cohort and revealed non-linear associations between placental Cd concentrations and placental area, perimeter, and volume which were stronger in Quartiles 2 (1.03 – 1.5 ng Cd/g) and 3 (1.5 – 1.8 ng Cd/g) and nonsignificant in Q4 (1.9 – 2.9 ng Cd/g) compared to the lowest quartile of Cd exposure. Male infants exhibited the strongest associations which were robust and present in all quartiles when excluding placentas from pregnancies with obstetric complications. Together, this research reveals that following gestational exposure to Cd, the placentas of male offspring may be more sensitive to toxicity. Furthermore, this research demonstrated the protective role of the Bcrp transporter in limiting placental accumulation and toxicity of Cd. This dissertation provides novel insights into mechanisms regulating adverse placental health following toxic metal exposure and advances the fields of environmental toxicology and epidemiology.
Comparison of commercial nano LC columns for fast, targeted proteomics of cancer cells
Creators: name: Wilson, Steven Ray
Publisher: name: figshare
Year: 2015
Subjects: Cancer
Biological Techniques

description: Targeted proteomics through nanoLC-MS/MS has the potential to measure several proteins in a complex sample in reasonable analysis time. However, to be a contender to existing methods; WB and ELISA, sample preparation has to be minimized, sensitivity high and analysis time short. We compared four commercially available nanoLC columns with various morphologies (Chromolith® (silica monolith), PepMap™ (porous particles), Accucore™ (solid core particles), and PepSwift™ (organic monolith)) for determination of Wnt/beta-catenin related pathway proteins in unfractionated/undepleted cell samples with gradients of 30 minutes. We found that the solid core particle packed column outperformed the other columns in terms of peak capacity (~190 at 50% peak height in 30 minutes). The average LC retention time shift was also least for the two particle based columns (<1 minute), whereas the monoliths were more prone to retention time instability when sample complexity increased. This will affect selectivity of identifications in a complex background, and effectively reduce assay robustness. Of the particle-packed columns, the solid core particle column had the best retention time repeatability in complex samples (1 % RSD). Only small difference in sensitivity was observed, even if the flow-rate was altered in the range of 200 – 600 nL/min. With the solid core particle packed column, Wnt/beta-catenin signal pathway members beta-catenin and GSK3beta were easily identified in non-fractionated samples and could be measured precisely (below 10 % variation) in complex backgrounds using SILAC labeled cell lines as internal standard which corrects for each sample preparation step and LC-MS variation. However, less abundant pathway proteins such as AXIN2 or TNKS2 could not be detected, perhaps calling for more narrow LC columns for fast trace analysis.
Governmental measures regarding COVID-19: Are Germany's right-wing populists losing out while the government gains support?
Creators: name: Weissenberg, Melanie
Publisher: name: Zenodo
Year: 2020

description: Weißenberg, M. (April 17, 2020) Governmental measures regarding COVID-19: Are Germany’s right-wing populists losing out while the government gains support?, Istanbul Bilgi University PRIME Youth Website. https://bpy.bilgi.edu.tr/en/blog/governmental-measures-regarding-covid-19-are-germa/
A broadly applicable artificial selection system for biomolecule evolution
Creators: name: Selles Vidal, Lara
Publisher: name: Imperial College London
Year: 2019

description: Biocatalysis offers an attractive alternative to traditional chemical catalysis. However, it is often found that an enzyme with the optimal properties for a specific application is not available within the natural repertoire of enzymes. It is then desirable to obtain an improved variant by altering the sequence of a known enzyme, in a process known as protein engineering. Directed evolution is one of the most powerful tools for protein engineering. In directed evolution, the process of natural evolution is mimicked in the laboratory at a much shorter timescale and selecting for properties that make the enzyme (or any other type of biomolecule) more suitable for an application of human interest. The main bottleneck of directed evolution is the identification of the desired variants amongst a majority of variants without the sought altered or improved property. Selection approaches link the desired activity to an increased survival rate or improved growth. While in principle such methodologies allow for ultra high-throughput analysis of libraries, most selection techniques have a limited scope, and can only be applied to a relatively reduced set of biomolecules or properties. This thesis presents the most broadly-applicable artificial selection system for the evolution of biomolecules ever reported. The selection platform is based on an engineered E. coli strain with impaired regeneration of NAD+, causing a conditional growth defect during anaerobic fermentation. By directly or indirectly linking the activity of the biomolecules of interest to the oxidation of NADH, cells can be rescued from this growth defect. The efficacy of such selection system has been demonstrated by using it to select alcohol dehydrogenase, imine reductase and nitroreductase variants with altered or enhanced catalytic properties, as well as an isopropanol-producing metabolic pathway with optimised regulatory elements leading to a maximised yield of isopropanol. These results confirm the wide scope of the developed selection system, which can replace conventional screening currently used in many cases of direct relevance for industrial processes. Increasing the throughput of the variant search process by many orders of magnitude will lead to the discovery of novel biomolecules and accelerate the implementation of biocatalysis.
HYBRID WORK MODEL AND EMPLOYEE JOB SATISFACTION AMONG SELECTED CONSULTANCY FIRMS IN ENUGU STATE
Creators: name: Juliet Anuri, Onwuchekwa
name: Chizoba Bonaventure, Okolocha
Publisher: name: American serial
Year: 2024
Subjects: Hybrid work model, Autonomy, Flexibility and job satisfaction

description: This study ascertained the effect of a hybrid work model on employee job satisfaction, using selected consultancy firms in Enugu State. Survey research design was adopted. Data were generated from the questionnaires distributed to the respondents, and were tested with regression analysis. Based on the analysis, the study found that there is a significant relationship existing between autonomy and job satisfaction of employees in consultancy firms in Enugu State.; and, the study indicated that there is a significant relationship existing between flexibility and the job satisfaction of employees in consultancy firms in Enugu State. Based on findings, the study recommended among others that the organization should not relent in implementation of workplace autonomy as this has been shown to have numerous benefits for both employees and organizations; hence, it is a vital component of employee job satisfaction and productivity.
Predicting change impact in architecture design with bayesian belief networks
Creators: name: Tang, Antony
name: Jin, Yan
name: Han, Jun
name: Nicholson, Ann
Publisher: name: Swinburne
Year: 2024

description: Research into design rationale in the past has focused on the representation of reasons and has omitted the connections between design rationales and design artefacts. Without such connections, designers and architects cannot easily assess how changing requirements or designs may affect the system. In this paper, we introduce a model called Architecture Rationale and Element Linkage (AREL) to represent the causal relationship between architecture elements and decisions. We further model AREL as a Bayesian Belief Network (BBN) to capture the probabilistic relationships between architecture elements and decisions in an architecture design model. Such probabilistic modelling enables architects to quantitatively predict and diagnose impact of change when part of the requirements or designs are changing. Using a partial design of a cheque image processing system, we illustrate how AREL is used to represent the decision model and how BBN is used to predict and diagnose change in the architecture design. We use a UML tool to capture the AREL model and a BBN tool to compute the probabilities of change impact.
Sensory feedback for supernumerary limbs
Creators: name: Blondin, Camille Mirka
Publisher: name: Imperial College London
Year: 2021

description: Supernumerary robotic limbs (SL) are devices developed to increase human capability. For this to happen, SLs should assist users with minimal cognitive effort and be controlled both independently and in combination with the user’s natural limbs. Despite the development of many SL, their application is limited by a lack of easy-to-use and intuitive controllers. Integrating somatosensory feedback in the control loop could improve this issue. In particular, providing artificial proprioception, a somatosensory modality important for motor control, could help SL users to integrate the SL into their planning and body schema. My objective is to find strategies to deliver intuitive and understandable proprioceptive feedback from a SL. To do so, I investigated possible ways of providing artificial proprioceptive feedback using 2degrees of freedom (DoFs) tactile cues delivered through electrical stimulation and vibration. I designed a set of mappings that provide position cues from a virtual arm for each feedback modality. Two studies, one for each modality, were conducted. In the first study, I observed that the intensity of electrical stimulation affected its perception and comfort. I then found that it was easier to differentiate frequency variations than intensity variations. This study brings new insights into electrical stimulation perception and mapping design, considering comfort is rarely addressed in previous studies. In the second study, I compared two mappings, task space and joint space, for the feedback and control of a virtual arm. Although I did not observe any effect on the performance, I found that the task space mapping was preferred and better understood than the joint space mapping. Furthermore, a novel vibration feedback device was designed and tested to deliver 3DoFs position cues. The study showed that it is possible to transmit feedback at the torso and back, a location that few studies have considered. Moreover, this study proposes a novel strategy to provide 3DoFs feedback using vibration alone.
Amberinone, a new guaianolide from Amberboa ramosa
Creators: name: Ibrahim, Muhammad
name: Hussain, Amjad
name: Akash, Muhammad Sajid Hamid
name: Hussain, Shabbir
name: Hussain, Iqbal
name: Hussain, Nusrat
name: Arruje Hameed
name: Farooq, Tahir
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Microbiology
subject: Biochemistry

description: The Amberboa is a medicinally important genus present in the family Asteraceae; members of this genus are mainly distributed in Pakistan and India. It has been used in different systems of traditional medicines for different diseases. Amberinone (1), a new sesquiterpene lactone, has been isolated from the ethyl acetate (EtOAc) soluble fraction of Amberboa ramosa together with chrysin (2), quercitine (3), eriodictyol (4) and keamferol (5). This is the first report of these compounds from this species. The structures of the isolated compounds have been elucidated by 1D and 2D 1H 13C NMR spectroscopy.
Software testing education and training in Hong Kong
Creators: name: Chan, F. T.
name: Tse, T. H.
name: Tang, W. H.
name: Chen, Tsong
Publisher: name: Swinburne
Year: 2024

description: While the use of computer applications is widely spread in every business and, hence, the reliability of software is critical, it is believed that many organizations involved in software development do not take software testing sufficiently seriously as an important task. It is worthwhile to find out how far organizations are carrying out software testing in a systematic and structured manner or still taking on an ad-hoc approach. A survey was conducted to understand the software testing practices and the level of related education and training in Hong Kong. It was found that most testing team members did not have formal training in software testing. University curricula generally did not prepare graduates with enough coverage in software testing. It is proposed that a review of the current software engineering curricula in the universities to examine the coverage of software testing will be useful to the development of quality software.
Investigating novel transcriptional regulators of AURKB and their implications in cancer
Creators: name: Begum, Parvin
Publisher: name: Imperial College London
Year: 2019

description: The Aurora B kinase regulates key processes and checkpoints during mitosis. Abnormalities of Aurora B result in aneuploidy and chromosomal instability. It is overexpressed in many cancers and associated with earlier metastasis and poorer prognosis. The work in this thesis sought to investigate the promoter and 5' region of AURKB, between it and neighbouring gene CTC1, to test the hypothesis that it contains sequences that can highlight novel regulators of the gene. In silico analysis of the region followed by experimental validation of candidate factors was carried out. The results propose lincRNA, Linc00324 as a novel regulator of AURKB, and able to reduce promoter activity. Analysis of datasets from the Cancer Genome Atlas revealed a highly statistically significant link between Linc00324 and AURKB mRNA expression in breast invasive carcinoma, with a tendency towards under-expression of this lncRNA in samples where AURKB was overexpressed. Transcription factors (TFs), AHR, BACH1, EGR1, and HIF1- were identified to have predicted transcription factor binding sites (TFBS) in both the AURKB promoter and Linc00324. The results of EMSA experiments, supported the binding of EGR1 and BACH1 to predicted TFBSs within the AURKB promoter. Analysis of ENCODE ChIP-seq data confirmed enrichment of EGR1 and BACH1 at the AURKB promoter region and at Linc00324. These transcription factors also caused a dose-dependent increase of AURKB promoter activity, in gene reporter assays. The candidate TFs are all, either hypoxia-responsive or involved in orchestrating the adaptive response to hypoxia through transcriptional regulation of target genes. Cobalt chloride was used to mimic hypoxia in experiments and results showed reduced activity of the AURKB promoter. Hypoxia is therefore proposed as a condition that can influence AURKB promoter activity and provides a mechanistic link to the identified TFs and potentially Linc00324. This has implications for the potential dysregulation of AURKB in cancer, within hypoxic intra-tumoral environments.
Phytochemical analysis and antioxidant potential of the leaves of Garcinia travancorica Bedd.
Creators: name: K.B. Rameshkumar
name: A.P. Anu Aravind
name: K.R.T. Asha
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Microbiology
subject: Biochemistry

description: Phytochemical analysis of the leaves of Garcinia travancorica, a hitherto uninvestigated endemic species to the Western Ghats of south India, resulted in isolation and characterisation of the polyisoprenylated benzophenones 7-epi-nemorosone (1) and garcinol (2) along with biflavonoids GB-1a (3), GB-1 (4), GB-2 (5), morelloflavone (6) and morelloflavone-7″-O-β-d-glycoside or fukugiside (7). The compounds were identified using various spectroscopic techniques, mainly through NMR and MS. The methanol extract and the biflavonoids 3, 4, 5 and 7 showed potential in vitro antioxidant activities. The IC50 value of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity of compound 7 was 8.34 ± 2.12 μg/mL, comparable to that of standard ascorbic acid (3.2 ± 0.50 μg/mL). In the superoxide radical scavenging assay, compound 7 gave IC50 value of 6.95 ± 1.33 μg/mL close to standard ascorbic acid with IC50 value of 5.8 ± 0.25 μg/mL. Validated HPTLC estimation revealed G. travancorica as a rich source of morelloflavone-7″-O-β-d-glycoside (7.12% dry wt. leaves).
Effect of Viscous Forces on the Performance of a Surging Wave Energy Converter
Creators: name: Bhinder, M.A.
name: Babarit, Aurélien
name: Gentaz, Lionel
name: Ferrant, Pierre
Publisher: name: figshare
Year: 2015
Subjects: subject: Oceanography
subject: FOS: Earth and related environmental sciences
subject: Mechanical Engineering
subject: FOS: Mechanical engineering

description:
Erratum: In Table 1, units of amplitude are [m/s] as this refers to velocity amplitude.Majid A. Bhinder, Aurélien Babarit, Lionel Gentaz and Pierre Ferrant, Effect of Viscous Forces on the Performance of a Surging Wave Energy Converter, Twenty-second International Offshore and Polar Engineering Conference ISOPE, Rhodes, Greece, 2012.
Evaluation of the highly-cited researchers’ database for a country: Proposals for meaningful analyses on the example of Germany
Creators: name: Bornmann, Lutz
name: Bauer, Johann
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: In 2014 Thomson Reuters (TR, provider of the Web of Science, WoS) published a list of highly-cited researchers worldwide. This includes those scientists who have published the most papers in their discipline which belong to the 1% of the most-cited papers. Bornmann and Bauer (in press) have presented a first evaluation in which the scientists are evaluated on the basis of their affiliations. In this short communication we would like to indicate how the TR data can be used to perform a meaningful country-specific evaluation. Germany serves as the example for the analysis.
Collaborative business transactions management: Issues and challenges
Creators: name: Zhang, Yanchun
name: Yang, Jian
name: Liu, Chengfei
Publisher: name: Swinburne
Year: 2024

description: This tutorial seeks to discuss the key concepts in collaborative business transaction management. Its intent is to explain the concept in business transaction and how it is different from traditional database transaction and workflow transaction management, to evaluate existing approaches, and to present existing techniques from other areas that can be adopted for business transactions and their limitations, and lastly to discuss a framework that addresses the challenges that are unique to business transaction management in the service oriented environment.
Phenylsulfonylacetic acid: condensations onto aryl aldehydes
Creators: name: Forbes, David C.
name: South, Mike S.
name: Rengasamy, Rajesh
name: Adirika J. Obiako
name: Battiste, David R.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Information and Computing Sciences
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Biochemistry

description: A study involving scope in the condensation reaction of phenylsulfonylacetic acid with a series of carbonyl derivatives has been conducted. Reactivity trends favor formation of the corresponding vinyl sulfones when working with aryl aldehydes. Electron-deficient aryl aldehydes outperform electron-rich aryl aldehydes. Negligible differences were noted when using electron-rich and electron-deficient arylsulfonylacetic acid derivatives. Post-run analyses of the reaction mixture reveal formation of a minor product which resulted from methylidene transfer onto the carbonyl derivative. Support of a Knoevenagel-type condensation followed by decarboxylation is provided.
MEASURING KIDNEY TO ABDOMINAL AORTA RATIO USING ULTRASONOGRAPHY TO DETERMINE KIDNEY SIZE IN HEALTHY DOMESTIC SHORTHAIR CATS
Creators: name: Peyman Mirmohammadi, Amir Ali Raissi
Publisher: name: TuEngr Group
Year: 2019
Subjects: Kidney length
Ultrasonography method
Aorta thickness
Cat renal disease
Kidney to aorta ratio.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 8, 1053-1060
MPEC 2024-V12 : 2024 UQ11
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 UQ11

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
High-resolution imaging beneath the Santorini volcano
Creators: name: Chrapkiewicz, Kajetan Marcin
Publisher: name: Imperial College London
Year: 2021

description: Volcanoes are surface expressions of much deeper magmatic systems, inaccessible to direct observation. Constraining the geometry and physical properties of these systems, in particular detecting high melt fraction (magma) reservoirs, is key to managing a volcanic hazard and understanding fundamental processes that lead to the formation of continents. Unfortunately, unambiguous evidence of magma reservoirs has not yet been provided due to the limited resolving power of the geophysical methods used so far. Here, a high-resolution imaging technique called full-waveform inversion was applied to study the magmatic system beneath the Santorini volcanic field, one of the most volcanically and seismically active regions of Europe. Quality-controlled inversion of 3d wide-angle, multi-azimuth ocean-bottom seismic data revealed a previously undetected high melt fraction reservoir 3 km beneath the Kolumbo volcano, a centre of microseismic and hydrothermal activity of the field. To enable the above method to handle land data, two major algorithmic improvements were added to the high-performance inversion code. First, to simulate instrument response of land seismometers, a pressure-velocity conversion has been implemented in a way that ensures reciprocity of the discretised 2nd-order acoustic wave equation. Second, the immersed-boundary method, originally developed for computational fluid dynamics, was implemented to simulate the wave-scattering off the irregular topography of the Santorini caldera. These advancements can be readily used to provide a higher-resolution image of the melt reservoir beneath the Santorini caldera already detected by means of travel-time tomography.
Symbiotic deep learning for medical image analysis with applications in real-time diagnosis for fetal ultrasound screening
Creators: name: Budd, Samuel
Publisher: name: Imperial College London
Year: 2021

description: The last hundred years have seen a monumental rise in the power and capability of machines to perform intelligent tasks in the stead of previously human operators. This rise is not expected to slow down any time soon and what this means for society and humanity as a whole remains to be seen. The overwhelming notion is that with the right goals in mind, the growing influence of machines on our every day tasks will enable humanity to give more attention to the truly groundbreaking challenges that we all face together. This will usher in a new age of human machine collaboration in which humans and machines may work side by side to achieve greater heights for all of humanity. Intelligent systems are useful in isolation, but the true benefits of intelligent systems come to the fore in complex systems where the interaction between humans and machines can be made seamless, and it is this goal of symbiosis between human and machine that may democratise complex knowledge, which motivates this thesis. In the recent past, datadriven methods have come to the fore and now represent the state-of-the-art in many different fields. Alongside the shift from rule-based towards data-driven methods we have also seen a shift in how humans interact with these technologies. Human computer interaction is changing in response to data-driven methods and new techniques must be developed to enable the same symbiosis between man and machine for data-driven methods as for previous formula-driven technology. We address five key challenges which need to be overcome for data-driven human-in-the-loop computing to reach maturity. These are (1) the ’Categorisation Challenge’ where we examine existing work and form a taxonomy of the different methods being utilised for data-driven human-in-the-loop computing; (2) the ’Confidence Challenge’, where data-driven methods must communicate interpretable beliefs in how confident their predictions are; (3) the ’Complexity Challenge’ where the aim of reasoned communication becomes increasingly important as the complexity of tasks and methods to solve also increases; (4) the ’Classification Challenge’ in which we look at how complex methods can be separated in order to provide greater reasoning in complex classification tasks; and finally (5) the ’Curation Challenge’ where we challenge the assumptions around bottleneck creation for the development of supervised learning methods.
SGIS v.R LiDAR Data Processing: Visualizing Point Clouds by Intensity
Creators: name: Gjorgjieva, Elena
name: Gjorgjiev, Kiro
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Earth and related environmental sciences
subject: FOS: Earth and related environmental sciences
subject: Geographic information systems
subject: Construction engineering
subject: Transportation engineering
subject: Urban engineering
subject: Science and technology studies
subject: Other engineering and technologies
subject: FOS: Other engineering and technologies
subject: Engineering and technology
subject: FOS: Engineering and technology
subject: Technology Development
subject: Green IT
subject: Green Software Development
subject: GIS software
subject: algorithms
subject: Algorithm Development
subject: LIDAR
subject: Remote sensing
subject: Geodesy
subject: Civil engineering
subject: FOS: Civil engineering
subject: Information engineering

description: SGIS v.R is enhancing this capability by offering tools to generate intensity-based images directly from LiDAR data.

Users will be able to seamlessly switch between classification and intensity views while working, adding a new layer of detail to their analysis. This flexibility can be especially valuable, providing clearer insights into surface characteristics and improving the precision of feature detection.
Stochastic maximum principle with control-dependent terminal time and applications
Creators: name: Cesari, Riccardo
Publisher: name: Imperial College London
Year: 2021

description: In this thesis we study stochastic control problems with control-dependent stopping terminal time. We assess what are the methods and theorems from standard control optimization settings that can be applied to this framework and we introduce new statements where necessary. In the first part of the thesis we study a general optimal liquidation problem with a control-dependent stopping time which is the first time the stock holding becomes zero or a fixed terminal time, whichever comes first. We prove a stochastic maximum principle (SMP) which is markedly different in its Hamiltonian condition from that of the standard SMP with fixed terminal time. The new version of the SMP involves an innovative definition of the FBSDE associated to the problem and a new type of Hamiltonian. We present several examples in which the optimal solution satisfies the SMP in this thesis but fails the standard SMP in the literature. The generalised version of the SMP Theorem can also be applied to any problem in physics and engineering in which the terminal time of the optimization depends on the control, such as optimal planning problems. In the second part of thesis, we introduce an optimal liquidation problem with control-dependent stopping time as before. We analyze the case when an agent is trading on a market with two financial assets correlated with each other. The agent’s task is to liquidate via market orders an initial position of shares of one of the two financial assets, without having the possi- bility of trading the other stock. The main results of this part consist in proving a verification theorem and a comparison principle for the viscosity solution to the HJB equation and finding an approximation of the classical solution of the Hamilton-Jacobi-Bellman (HJB) equation associated to this problem.
Instrumento para la validación de un registro de observación de interacciones para grupos interactivos en Comunidades de Aprendizaje
Creators: name: Galafat-Hurtado, Álvaro
name: Vega, Noelia Rute
name: Aguaded-Ramírez, Eva
name: Carrillo-Rosúa, Javier
Publisher: name: figshare
Year: 2015
Subjects: Education

description: Este documento corresponde con un instrumento para la validación de un registro de observación de interacciones en grupos interactivos del proyecto educativo de Comunidades de Aprendizaje. Consiste en una escala de estimación descriptiva que no solo tiene en cuenta la presencia o ausencia del rasgo, sino, también, la intensidad con la que aparece.
Lexim kritik i disa librave të fizikës për shkollat e mesme të Kosovës
Creators: name: Gojani, Ardian B.
Publisher: name: figshare
Year: 2015
Subjects: Education

description: Kumtesë nga konferenca Java e shkencës, 13 maj 2015, Prishtinë. Kumtesa kritikon MASHT-in për aprovimin e disa teksteve shkollore për lëndën e fizikës e që kanë gabime të mëdha shkencore. A talk presented at the Science Week, May 13, 2015, Prishtina. The paper criticizes MEST for approving some physics textbooks which are full of scientific errors.
Erratum: Viscosity of confined inhomogeneous nonequilibrium fluids (The Journal of Chemical Physics (2004) 121 (10778))
Creators: name: Zhang, Junfang
name: Todd, Billy
name: Travis, Karl P.
Publisher: name: Swinburne
Year: 2024

description: Corrects an error in: Zhang, J., Todd, B. D., & Travis, K. P. (2005). Viscosity of confined inhomogeneous nonequilibrium fluids. Journal of Chemical Physics, 121 (21), 10778-10786. For the original article, see: http://hdl.handle.net/1959.3/439.
Nanospheres Chitosan as a Targeted Drug Delivery System
Creators: name: Sarvesh Kumar Pathak
name: Pathak, Sandeep Kumar
name: Upadhyay, Laxmi
Publisher: name: figshare
Year: 2015
Subjects: Biological Engineering

description: Biodegradable nanospheres carriers, have important potential applications for administration of therapeutic molecules. Chitosan (CS) based nanospheres have attracted a lot of attention upon their biological properties such as biodegradability, biocompatibility, bioadhesivity and can reduce systemic side effects and allow for more efficient use of the drug. chitosan is a natural polymer obtained by deacetylation of chitin. After cellulose chitin is the second most abundant polysaccharide in nature. In the present study deals with the formulation and evaluation of surfactant coated and uncoated chitosan nanospheres and its various uses.
Keywords: Chitosan , formulation and evaluation , nanospheres
Bakker et al 2020 Improving mental health of student and novice nurses to prevent dropout (review).pdf
Creators: name: Bakker, Ellen
name: Kox, Jos
name: Boot, Cecile R. L.
name: Francke, Anneke L.
name: van der Beek, Allard
name: Roelofs, Pepijn D. D. M.
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 399999
subject: Other education not elsewhere classified
classificationCode: 420505
subject: Nursing workforce
classificationCode: 420599
subject: Nursing not elsewhere classified

description: Aims: To provide: (a) an overview of interventions aimed at improving mental health of student or novice nurses; and (b) an evaluation of their effectiveness on dropoutrelated outcomes. Design: Systematic review. Data sources: Research papers published between January 1971–February 2019 were identified from the following databases: Embase, Medline, PsycInfo, CINAHL, ERIC, the Cochrane Library, Web of Science, and Google Scholar. Review methods: We followed the procedures recommended by the Editorial Board of the Cochrane Collaboration Back Review Group. We included peer-reviewed articles with a quantitative research design, examining interventions aimed at improving mental health of student and novice nurses and their effect on dropout-related outcomes. The large variation in studies prohibited statistical pooling and a synthesis without meta-analysis of studies was performed. Results: We identified 21 studies with three areas of focus: managing stress or stressors (N = 4); facilitating the transition to nursing practice (N = 14); and a combined approach (N = 3). Five studies showed a statistically significant effect on dropoutrelated outcomes. The overall risk of bias was high. Conclusion: A wide range of interventions are available, but the evidence for their effectiveness is limited. There is a need for high-quality studies in this field, preferably with a randomized controlled design.
Alan Turing Institute Environment and Sustainability Grand Challenge: Stakeholder Mapping and Community Strategy
Creators: name: Gould van Praag, Cassandra
Publisher: name: Zenodo
Year: 2024

description: Presentation for UK Earth Observation Framework 2024.

I will present the community management strategy and activity of the Alan Turing Institute Environment and Sustainability Grand Challenge. This strategy is designed to scaffold engagement with this programme of work, and between community members. This scaffolding is the mechanism by which we can bring varied (and under-represented) researchers into conversation to distil and communicate best practices, and foster conversation about the complex spaces we work in, while directing and responding to those challenges. I will propose that resourcing of formal management of a community, and community-centred collaboration, are essential to equitable and impactful AI in the environmental observation sector.
Experimentally derived interactions between TCP traffic and service quality over DOCSIS cable links
Creators: name: Nguyen, Thuy T.T.
name: Armitage, Grenville
Publisher: name: Swinburne
Year: 2024

description: We study the effect of upstream (US) and downstream (DS) rate caps and DOCSIS media access on the end-to-end performance of broadband IP services that share a typical home-access 'cable Internet' link. Our experimental study measures the performance of actual DOCSIS equipment in a typical network configuration. We observe that modestly long lived data transfers in the DS direction can create substantial latency spikes (over 100 ms) in the shared DOCSIS segment, even when the DS rate cap is one or two megabits per second. Such spikes can have a big impact on delay-sensitive applications, such as voice over IP (VoIP), online games and interactive streaming video that may be sharing the DOCSIS link. We also experimentally characterize the impact of US and DS bandwidth asymmetry, MTU sizes, and TCP window sizes in achieving maximum performance over DOCSIS links.
A packet arrival model for wolfenstein enemy territory online server discovery traffic
Creators: name: Armitage, Grenville
Publisher: name: Swinburne
Year: 2024

description: Clients for online multiplayer first person shooter (FPS) games typically discover game servers through a two-step process. Clients initially query a well-known master server for a list of currently registered game servers, and then sequentially probe each game server in the order they were returned by the master server. The starting and stopping of clients over time creates a 24-hour cycle of 'background noise' (probe traffic) impacting on registered game servers, independent of a given server's actual popularity with players. Based on over 10 million probe packets from two topologically distinct Wolfenstein Enemy Territory servers in 2006, this paper shows that probe arrivals are uncorrelated and exhibit exponentially distributed inter-probe intervals during both busiest and least-busy hours of the 24-hour cycle. A modified Laplace curve is then shown to be a reasonable estimator of lambada for the exponentially distributed probe arrivals during any hour of the day. The ability to easily synthesise probe traffic patterns will augment existing approaches to modeling the IP traffic loads experienced by game servers and network devices attached to game servers.
Random scattering of surface plasmons for sensing and tracking
Creators: name: Berk, Joel Andrew
Publisher: name: Imperial College London
Year: 2021

description: In this thesis, a single particle biosensing setup, capable of sensing and tracking single nanoscale biological particles, is proposed and investigated theoretically. The setup is based on monitoring the speckle pattern intensity distribution arising due to random scattering of surface plasmon polaritons (SPPs) from a metal surface. An analyte particle close to the surface will additionally scatter light, perturbing the speckle pattern. From this speckle pattern perturbation, the analyte particle can be detected and tracked. Theoretical sensitivity analysis predicts a biological particle on the order of 10nm in radius gives a fractional intensity perturbation to the speckle intensity of 10^4, comparable to intensity contrasts used in existing interferometric scattering sensing techniques. A formula for the minimum detectable particle size is derived. In addition, an algorithm is derived capable of extracting the particle trajectory in the single scattering regime from the change to the speckle intensity perturbation over time and shown to be capable of errors of approximately 1nm on simulated data under optimal noise conditions. The effect of multiple scattering on the speckle pattern perturbation is studied, and it is shown that, by tuning the scattering mean free path and individual scatterer properties of a random nanostructure of scatterers on the metal surface, one can increase the magnitude of the speckle field perturbation by up to the order of 10^2. A neural network based localisation algorithm is developed to calculate the analyte particle position based on the speckle intensity perturbation and its performance on simulated data is studied. Mean errors on the order of 20nm were found, depending on the size of the region over which the particle must be tracked. Unlike the single scattering tracking algorithm, the neural network algorithm continues to function in the multiple scattering regime.
MPEC 2024-V13 : 2024 UR11
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 UR11

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: In situ-Diffraktometrie an heterogenen Katalysatoren
Creators: name: Heck, Franziska Rosa-Maria
Publisher: name: UNSPECIFIED
Year: 2024

description: Diese Arbeit widmet sich der Grundlagenforschung zur Eignung eisenbasierter anorganischer Verbindungen als Katalysatoren für die oxidative Dehydrierung von Ethanol. Sie untersucht Eisen(III)molybdate und Eisen(III)wolframate als potenzielle Katalysatoren für die oxidative Dehydrierung von (Bio-)Ethanol, wobei der Schwerpunkt auf in situ-diffraktometrischen Analysen während der Reaktion liegt. Darüber hinaus wurde der Einfluss unterschiedlicher Synthesemethoden auf die katalytischen und chemischen Eigenschaften der Katalysatoren untersucht. Ein weiterer Fokus lag auf der Untersuchung der Rolle der Nebenphase MoO₃ in Fe₂(MoO₄)₃/MoO₃-Gemischen mit unterschiedlichen Mo-Verhältnissen (1,5:1 bis 3:1). Diese Arbeit liefert wertvolle Einblicke in die Verwendung von Fe-Mo- und Fe-W-Oxiden als Katalysatoren für die oxidative Dehydrierung von Ethanol.
IMPACT OF INNOVATIVE SALINITY LEACHING AND IRRIGATION TECHNOLOGY ON SALT BALANCE IN EXPERIMENTAL FIELDS.
Creators: name: Atamurodov, B.N.
name: Juraev, U.A.
Publisher: name: Zenodo
Year: 2024

description: This article presents the results of field experiments on salt leaching and water-saving irrigation technology for cotton in the heavily saline, heavy loam soils of the long-irrigated alluvial meadows of Bukhara region. The study evaluates salt balance, with results showing that salt content decreased by 3.3 t ha-1 in the second variant and by 7 t ha-1 in the third variant compared to the control.
Measuring the quality of information managed: some conceptual and methodological reflexions
Creators: name: González-Valiente, Carlos Luis
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: The study, based on a documental classic analysis, presents conceptual and methodological guidelines concerning the design of methodologies that help to measure the quality of information that is managed in organizations. It is described the process of information management and the importance of implementing quality principles in it. There are exposed the four dimensions of information quality as part of an indicators integration which characterize the informational contents. There are defined each of the phases in the methodological design to evaluate the information. There also are indicated the implications of this activity for information professionals.
A MODEL DEVELOPMENT FOR HOSPITAL HOLDING GOVERNANCE IN THE IRANIAN SOCIAL SECURITY ORGANIZATION
Creators: name: Farideh Mohammadi, Iravan Masoudi Asl
Publisher: name: TuEngr Group
Year: 2019
Subjects: Healthcare quality
Healthcare strategic planning
Healthcare management
Healthcare evaluation, and accountability
Healthcare financing
ISSO.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 8, 1061-1069
Proposal for an information literacy program for students at the University of Havana
Creators: name: González-Valiente, Carlos Luis
name: Yilianne Sánchez Rodríguez
name: Yazmín Lezcano Pérez
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: Theoretical aspects associated with the design of information
literacy programs are boarded. Classic documentary analysis is used as a
research method. It makes the case for implementing these programs in
the university context. The results of an assessment of the skill level of University
of Havana students are presented. It is also presented the design
of information literacy program with all its content system, assessment
and other key elements of interest.
QUANTITATIVE METHODOLOGY FOR ASSESSING THE EFFECTIVENESS OF THE MANAGEMENT SYSTEM IN A STATE AUTHORITY OF THE TERRITORIAL AIC
Creators: name: M.V.Brazhnik
Publisher: name: TuEngr Group
Year: 2019
Subjects: Agro-based economy
Agro productivity
Efficiency of management
Competent management
Rationality management activity
Management of agricultural production.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 8, 1071-1081
Cuban research on information literacy: an analysis of published literature
Creators: name: González-Valiente, Carlos Luis
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: Objective: perform a bibliometric characterization of Cuban research on
information literacy (INFOLIT) based on the literature published from 2000 to 2013.
Methods: substantiation was provided for conceptual notions about INFOLIT in the
field of library and information sciences, and some interesting research antecedents
were explored. Sixty-seven papers identified by the Ibero-America-Cuba INFOLIT
Wiki-Repository were examined with the bibliometric indicators yearly productivity,
authors, journals and term co-occurrence analysis, as well as type of documents
cited, and most commonly cited journals and authors. Bibliometric maps and
graphs were used to present the results obtained.
Results: the topic has expanded since 2007. The most outstanding authors were
from health and higher education institutions. The most productive journals were
from the area of Library Science and Information Sciences in Cuba. Four basic
research lines were found: 1) INFOLIT in medical and health sciences, 2)
information competences among university students, 3) INFOLIT evaluation and 4)
design of INFOLIT syllabuses. The most commonly cited journals were ACIMED,
Anales de Documentación, Boletín de la Asociación Andaluza de Bibliotecarios, The
Journal of Academic Librarianship and Ciencias de la Información. Overseas authors
were more commonly cited.
Conclusions: the study shed light on the main Cuban patterns for research on
INFOLIT, a matter not examined previously, paving the way for the development of
the topic in library and information sciences.
Incorporation of information science graduates to marketing management tasks
Creators: name: González-Valiente, Carlos Luis
name: Santos, Magda León
name: Rivera, Zoia
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: The study aims to identify the possibilities offered by academic studies in Cuba for
the training of information professionals as marketing managers. A theoretical
analysis is conducted of the basic functions of marketing and its information
dimension, the specific features of the work of the marketing manager, and the competencies developed by Curriculum D in information science graduates in the
Cuban context. Based on the analysis of curricular contents and interviews with ten
information professionals working as marketing managers, determination was made
of some indispensable competencies which should be developed during the training
and later on during service practice.