cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Introduction to data management plans (DMP) - Presentation from webinar 2023-02-03
Creators: name: Benedicte, Juhasz Ida
Publisher: name: Zenodo
Year: 2023
Subjects: Library
Data management plan
DMP
Research data management
FAIR
Open science
FAIR data

description: The presentation introduces Data Management Plans as tool to ensure good data handling practice in a research project and as required by research funders such as the Research Council of Norway or the Horizon Europe funding scheme. It gives an introduction to writing a data management plan for a research project in accordance with the Science Europe Practical Guide to the International Alignment of Research Data Management and specifically points out resources at the University of Bergen, Norway.
(103370) Fanny Louise Tricks
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
RING-SHAPED SPECIMEN FOR DIRECT TENSILE TEST MACHINE
Creators: name: Kumar, Parveen
name: Aggarwal, Vanita
name: Walia, Baljit Singh
Publisher: name: The patent office, Government of India
Year: 2024
Subjects: RING-SHAPED SPECIMEN FOR DIRECT TENSILE TEST MACHINE

description: Background technologyIn the field of rock mechanics, the most popular method for indirect tensile testing, such as the Brazilian indirect tensile strength test, involves using disc-shaped specimens to calculate the tensile strength of rock samples. However, during this testing procedure, researchers have observed the generation of compressive and shear stresses at the contact area between the specimen and the loading jaw of the testing machine. This has led to overestimated results. To address this issue, ring-shaped specimens were introduced. Nevertheless, in direct tensile testing machines, a gap between the contact area of the loading jaw and the specimen leads to inaccurate tensile strength measurements. Additionally, the angular movement of the disc during the loading process results in shear stresses, as the failure does not occur along the vertical or principal plane. The primary objective of this invention is to overcome these difficulties. This is achieved by minimizing the gap between the loading jaw and the specimen and preventing the angular movement of the disc during the loading procedure, all while maintaining ease of use.

DescriptionA kind of Ring-Shaped sample designed for use in a direct tensile testing machine.

Invention Field

The present invention relates to a kind of ring-shaped rock specimen designed for use in direct tensile test machine for testing the tensile strength property of rock material property.

Summary of the invention

The objective of this invention is to offer a specific type of ring-shaped specimen tailored for use in a direct tensile testing machine. The primary aim of the present innovation is to address the issue of overestimated experimental results in direct tensile testing for rock specimens. This is achieved by reducing the gap between the loading jaws and the specimen's contact area by incorporating grooves in opposite directions on the inner side of the ring-shaped specimen, located at the vertical plane. These grooves, cut into the inner diameter of the ring-shaped specimen, serve to snugly accommodate both the fixed and movable loading jaws of the testing machine, minimizing the gap between the loading jaws and the specimen's contact area. Furthermore, these groove cuts prevent angular movement during the testing procedure, ensuring that the specimen fails along its principal plane.
Network-based model of the growth of termite nests
Creators: name: Eom, Young-Ho
name: Perna, Andrea
name: Fortunato, Santo
name: Darrouzet, Eric
name: Theraulaz, Guy
name: Jost, Christian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Biological Physics (physics.bio-ph)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: We present a model for the growth of the transportation network inside nests of the social insect subfamily Termitinae (Isoptera, termitidae). These nests consist of large chambers (nodes) connected by tunnels (edges). The model based on the empirical analysis of the real nest networks combined with pruning (edge removal, either random or weighted by betweenness centrality) and a memory effect (preferential growth from the latest added chambers) successfully predicts emergent nest properties (degree distribution, size of the largest connected component, average path lengths, backbone link ratios, and local graph redundancy). The two pruning alternatives can be associated with different genuses in the subfamily. A sensitivity analysis on the pruning and memory parameters indicates that Termitinae networks favor fast internal transportation over efficient defense strategies against ant predators. Our results provide an example of how complex network organization and efficient network properties can be generated from simple building rules based on local interactions and contribute to our understanding of the mechanisms that come into play for the formation of termite networks and of biological transportation networks in general.
description: 11 pages, 5 figures. Published in Phy. Rev. E. Supplement materials are available at http://journals.aps.org/pre/supplemental/10.1103/PhysRevE.92.062810/YHE-TermiteNestModel-SM-V1.2.pdf
title: Conventional radiography in juvenile idiopathic arthritis: joined recommendations from the French societies for rheumatology, radiology, paediatric radiology
Creators: name: Marteau, Pauline
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Bones
subject: Musculoskeletal joint
subject: Paediatric
subject: Conventional radiography
subject: Decision analysis
subject: Education
subject: Safety
subject: Arthritides
subject: Demineralisation-Bone
subject: Dosimetric comparison

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To provide pragmatic guidelines concerning conventional radiography (CR)in each subtype of Juvenile Idiopathic Arthritis (JIA) (systemic JIA...
title: Diffusion kurtosis imaging in diffuse axonal injury: a novel diagnostic approach
Creators: name: Zakharova, Natalia
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Neuroradiology brain
subject: MR
subject: MR-Diffusion/Perfusion
subject: Diagnostic procedure
subject: Trauma

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Introduction: Diffusion imaging, based on Gaussian water diffusion detection, has been used in clinical practice for many years. DTI provides information regarding the degree and directionality of anisotropic water diffusion in tissues, thus...
title: Radiation dose comparison between photon counting and selenium mammography technology
Creators: name: Salvador Tarrason, Rafael
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Breast
subject: Radioprotection / Radiation dose
subject: Radiation physics
subject: Mammography
subject: Screening
subject: Diagnostic procedure
subject: Radiation safety
subject: Cancer
subject: Image registration

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To compare the radiation dose received by patients during a mammographic screening exam for breast cancer with photon counting detector (PCD) to the selenium detector...
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1
Creators: name: Tempel, W.
name: Min, J.
name: Stuckey, J.I.
name: Huber, K.G.
name: Black, K.
name: Liu, Y.
name: Cholensky, S.H.
name: Brown, P.J.
name: Qin, S.
name: Senisterra, G.
name: Pattenden, S.G.
name: Vedadi, M.
name: James, L.I.
name: Huang, X.-P.
name: Baughman, B.M.
name: Sagum, C.
name: Arrowsmith, C.H.
name: Dickson, B.M.
name: Norris, J.L.
name: Frye, S.V.
name: Li, F.
name: Roth, B.L.
name: Bedford, M.T.
name: Cheng, N.
Publisher: name: Nature Publishing Group
Year: 2016

description: We report the design and characterization of UNC3866, a potent antagonist of the methyllysine (Kme) reading function of the Polycomb CBX and CDY families of chromodomains. Polycomb CBX proteins regulate gene expression by targeting Polycomb repressive complex 1 (PRC1) to sites of H3K27me3 via their chromodomains. UNC3866 binds the chromodomains of CBX4 and CBX7 most potently, with a K d of â ∼1/4100 nM for each, and is 6-to 18-fold selective as compared to seven other CBX and CDY chromodomains while being highly selective over >250 other protein targets. X-ray crystallography revealed that UNC3866's interactions with the CBX chromodomains closely mimic those of the methylated H3 tail. UNC4195, a biotinylated derivative of UNC3866, was used to demonstrate that UNC3866 engages intact PRC1 and that EED incorporation into PRC1 is isoform dependent in PC3 prostate cancer cells. Finally, UNC3866 inhibits PC3 cell proliferation, consistent with the known ability of CBX7 overexpression to confer a growth advantage, whereas UNC4219, a methylated negative control compound, has negligible effects.
title: Balloon sacroplasty (BSP), radiofrequency sacroplasty (RFS), vertebrosacroplasty (VSP) and cement sacroplasty (CSP) for the treatment of insufficiency fractures
Creators: name: Andresen, Reimer
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Interventional non-vascular
subject: Musculoskeletal spine
subject: Neuroradiology spine
subject: CT
subject: Vertebroplasty
subject: Technical aspects
subject: Safety
subject: Osteoporosis

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: In elderly patients with reduced bone quality who experience suddenly occurring deep-seated low back pain, the possible presence of an insufficiency fracture in the sacrum should be considered as a differential diagnosis (1, 2). These fractures...
Cosmological Dynamics in Interacting Scalar-Torsion f(T,$ϕ$) Gravity: Investigating Energy and Momentum Couplings
Creators: name: Rodriguez-Benites, Carlos
name: Gonzalez-Espinoza, Manuel
name: Otalora, Giovanni
name: Alva-Morales, Manuel
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the cosmological dynamics of a homogeneous scalar field non-minimally coupled to torsion gravity, which also interacts with cold dark matter through energy and momentum transfer. The matter and radiation perfect fluids are modeled using the Sorkin-Schutz formalism. We identify scaling regimes of the field during both the radiation and matter eras. Additionally, we discovered a field-dominated scaling attractor; however, it does not exhibit accelerated expansion, making it unsuitable for describing dark energy. Nevertheless, we find two attractor solutions that do exhibit accelerated expansion: one is a quintessence-like fixed point, and the other is a de Sitter fixed point.
description: 18 pages, 8 figures. Updated to match the published version in PRD
title: Radiological management after bariatric surgery
Creators: name: Venetucci, Pietro
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Abdomen
subject: CT
subject: Conventional radiography
subject: Surgery
subject: Outcomes

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To illustrate an imaging protocol after bariatric surgery, based on upper gastrointestinal series (UGI) and multi-detector computed tomography (MDCT), in presence or in absence of...
title: MRI for detailed assessment of pancreatic morphology and function in chronic pancreatitis
Creators: name: Frøkjær, Jens Brøndum
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Pancreas
subject: Abdomen
subject: CNS
subject: MR
subject: MR-Functional imaging
subject: Ultrasound
subject: Imaging sequences

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Chronic pancreatitis (CP) is characterized by abnormal pancreatic morphology and impaired endocrine and exocrine function. Little is known about the relationship between pancreatic morphology and function in CP, and also its association to the...
(103371) Elsie Horwood Tricks
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: CT-guided pulsed radio frequency treatment of the lumbar dorsal root ganglion (DRG) in patients with acute and sub-acute radicular low back pain
Creators: name: Napoli, Alessandro
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Interventional non-vascular
subject: Musculoskeletal spine
subject: Percutaneous
subject: Efficacy studies
subject: Inflammation

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Low back pain is an extremely common problem that affects at least 80% of all individual at some point in their lifetime [1]. Lumbosacral disc herniation with dorsal nerve root compression represents an important causes of acute low back pain...
Chemogenetics-a transformational and translational platform
Creators: name: English, J.G.
name: Roth, B.L.
Publisher: name: American Medical Association
Year: 2015

description: Neurologic disorders are frequently a result of inappropriate electrical and/or chemical signaling of neurons and glia. Ultimate remediation would necessitate reprogramming these signals. Historically, correcting neuronal and glial signaling is accomplished via drug therapy/administration, although they frequently fail to effectively and fully treat the underlying disorder. Developments in basic research have produced several new classes of potential therapeutics to directly and precisely control neuron activity at the single-cell level. We review one such technology, Designer Receptors Exclusively Activated by Designer Drugs, and suggest its potential as a powerful tool for augmenting neuronal and glial signaling and activity for basic and translational applications. Copyright 2015 American Medical Association. All rights reserved.
Ising Model on Twisted Lattice and Holographic RG flow
Creators: name: Matsuura, So
name: Sakai, Norisuke
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The partition function of the two-dimensional Ising model is exactly obtained on a lattice with a twisted boundary condition. The continuum limit of the model off the critical temperature is found to give the mass-deformed Ising conformal field theory (CFT) on the torus with the complex structure $τ$. We find that the renormalization group (RG) flow of the mass parameter can be holographically described in terms of the three-dimensional gravity including a scalar field with a simple nonlinear kinetic function and a quadratic potential.
description: 27 pages, 3 figures, references added, comments added, typos corrected, a phase factor is added to the definition of the shift matrix, derivation of the partition function is refined
title: Non-invasive MR-guided focused ultrasound (MRgFUS) therapy is associated with bone integrity restoration in patients with osteoid osteoma
Creators: name: Scipione, Roberto
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Interventional non-vascular
subject: Musculoskeletal bone
subject: MR
subject: MR-Functional imaging
subject: CT
subject: Ablation procedures

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Osteoid Osteoma (OO) is a benign tumor that mainly affects pediatric population. The impact on quality of life is considerable, since OO is typically associated with nocturnal pain and limitations ineveryday or sportive activity. Currently, the most...
La mise en valeur de l'initiative VDMD dans les communications au Québec
Creators: name: Lalande, Justine
name: Yates, Stéphanie
name: Gendron, Corinne
Publisher: name: Zenodo
Year: 2022
Subjects: Mines
Mining industry
normes
Vers un développement minier durable

description: À l’heure où d’innombrables métaux et minéraux sont appelés à jouer un rôle crucial dans la transition énergétique qui vise un avenir plus sain et à faible intensité carbonique et plus largement dans la lutte mondiale contre le changement climatique, le secteur minier se doit de devenir de plus en plus durable. En 2004, l’Association minière du Canada (AMC) a mis sur pied l’initiative VDMD – Vers un développement minier durable (TSM© – Towards sustainable mining), une norme interne que tous leurs membres doivent respecter. Cette initiative a pour principal objectif de permettre aux entreprises minières de répondre aux besoins de la société en matière de produits minéraux, métalliques et énergétiques de la manière la plus responsable qui soit sur les plans social, économique et environnemental[1]. Nous proposons, dans un premier temps, de nous attarder au contexte de la création de cette norme, qui aura bientôt 20 ans, d’analyser ensuite la façon dont elle est mise en valeur (ou non) dans la sphère publique et enfin de poser un regard critique sur l’utilité cette norme interne de l’Association minière du Canada au regard de l’acceptabilité sociale. [1] Association minière du Canada, 2022. https://mining.ca/fr/vers-le-developpement-minier-durable/
title: Lung lesion motion in the z-axis during CT-guided lung biopsy is greater in the lower lung and after intravenous sedation
Creators: name: Allen, Grainne
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Lung
subject: Respiratory system
subject: CT
subject: Biopsy

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Introduction Lung lesion motion has been studied in the context of radiotherapy [1]and navigational bronchoscopy [2]but no studies examine the factors that might influence nodule motion during computed tomographic (CT) biopsy in the case of...
(103372) Edgar Wood Tricks
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(103367) Charles Edward Tricks
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Rejoinder to "Bayesian Model Selection Based on Proper Scoring Rules"
Creators: name: Dawid, A. Philip
name: Musio, Monica
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: We are deeply appreciative of the initiative of the editor, Marina Vanucci, in commissioning a discussion of our paper, and extremely grateful to all the discussants for their insightful and thought-provoking comments. We respond to the discussions in alphabetical order [arXiv:1409.5291].
description: Published at http://dx.doi.org/10.1214/15-BA942REJ in the Bayesian Analysis (http://projecteuclid.org/euclid.ba) by the International Society of Bayesian Analysis (http://bayesian.org/)
Proceedings of the Combined 22th International Workshop on Expressiveness in Concurrency and 12th Workshop on Structural Operational Semantics
Creators: name: Crafa, Silvia
name: Gebler, Daniel E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: This volume contains the proceedings of the Combined 22nd International Workshop on Expressiveness in Concurrency and the 12th Workshop on Structural Operational Semantics (EXPRESS/SOS 2015) which was held on 31 August 2015 in Madrid, Spain, as an affiliated workshop of CONCUR 2015, the 26th International Conference on Concurrency Theory. The EXPRESS workshops aim at bringing together researchers interested in the expressiveness of various formal systems and semantic notions, particularly in the field of concurrency. Their focus has traditionally been on the comparison between programming concepts (such as concurrent, functional, imperative, logic and object-oriented programming) and between mathematical models of computation (such as process algebras, Petri nets, event structures, modal logics, and rewrite systems) on the basis of their relative expressive power. The EXPRESS workshop series has run successfully since 1994 and over the years this focus has become broadly construed. The SOS workshops aim at being a forum for researchers, students and practitioners interested in new developments, and directions for future investigation, in the field of structural operational semantics. One of the specific goals of the SOS workshop series is to establish synergies between the concurrency and programming language communities working on the theory and practice of SOS. Since 2012, the EXPRESS and SOS communities have organized an annual combined EXPRESS/SOS workshop on the expressiveness of mathematical models of computation and the formal semantics of systems and programming concepts.
Discovery of β-arrestin-biased dopamine D 2 ligands for probing signal transduction pathways essential for antipsychotic efficacy
Creators: name: Huang, X.-P.
name: Roth, B.L.
name: Jensen, N.H.
name: Sassano, M.F.
name: Caron, M.G.
name: Bai, X.
name: Setola, V.
name: Wetsel, W.C.
name: Jin, J.
name: Yost, J.M.
name: Javitch, J.A.
name: Chen, X.
name: Feng, B.
name: Peterson, S.
name: Yadav, P.N.
name: Che, X.
name: Chen, M.
name: Allen, J.A.
name: Frye, S.V.
Publisher: name: National Academy of Sciences
Year: 2011

description: Elucidating the key signal transduction pathways essential for both antipsychotic efficacy and side-effect profiles is essential for developing safer and more effective therapies. Recent work has highlighted noncanonical modes of dopamine D 2 receptor (D 2R) signaling via β-arrestins as being important for the therapeutic actions of both antipsychotic and antimanic agents. We thus sought to create unique D 2R agonists that display signaling bias via β-arrestinergic signaling. Through a robust diversity-oriented modification of the scaffold represented by aripiprazole (1), we discovered UNC9975 (2), UNC0006 (3), and UNC9994 (4) as unprecedented β-arrestin-biased D 2R ligands. These compounds also represent unprecedented β-arrestin-biased ligands for a G i-coupled G protein-coupled receptor (GPCR). Significantly, UNC9975, UNC0006, and UNC9994 are simultaneously antagonists of G i-regulated cAMP production and partial agonists for D 2R/β-arrestin-2 interactions. Importantly, UNC9975 displayed potent antipsychotic-like activity without inducing motoric side effects in inbred C57BL/6 mice in vivo. Genetic deletion of β-arrestin-2 simultaneously attenuated the antipsychotic actions of UNC9975 and transformed it into a typical antipsychotic drug with a high propensity to induce catalepsy. Similarly, the antipsychotic-like activity displayed by UNC9994, an extremely β-arrestin-biased D 2R agonist, in wild-type mice was completely abolished in β-arrestin-2 knockout mice. Taken together, our results suggest that β-arrestin signaling and recruitment can be simultaneously a significant contributor to antipsychotic efficacy and protective against motoric side effects. These functionally selective, β-arrestin-biased D 2R ligands represent valuable chemical probes for further investigations of D 2R signaling in health and disease.
Speed of sound bounds and first-order phase transitions in compact stars
Creators: name: Laskos-Patkos, P.
name: Lalazissis, G. A.
name: Wang, Sibo
name: Meng, Jie
name: Ring, Peter
name: Moustakidis, Ch. C.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: In the present study, we employ three distinct, physically motivated speed of sound bounds to construct hybrid models, where the high-density phase is described by the maximally stiff equation of state. In particular, we consider the bounds related to special relativity, relativistic kinetic theory and conformality. The low-density hadronic phase is described by a state-of-the-art microscopic relativistic Brueckner-Hartree-Fock theory. This work aims to access the effect of the different speed of sound constraints on the relevant parameter space of the key parameters of first-order phase transitions by utilizing recent astronomical data. This involves a systematic analysis that also includes two distinct schemes for the construction of hybrid models (abrupt and smooth). Finally, a relevant discussion is conducted on the possible occurrence of a thermodynamic inconsistency that is related to the stability of the high-density phase over hadronic matter at large densities.
description: v1: 11 pages, 8 figures; v2: 12 pages, 10 figures; updated to match the published version; accepted for publication in Physical Review C
title: The signalling of managerial tone: evidence from the earnings conference calls
Creators: name: Ning, Jing
Publisher: name: University of Reading
Year: 2024

description: This thesis attempts to investigate the signalling role of managerial tone in the context of corporate disclosure. It first starts with a literature review in-depth to review how managers use their tone (roles) and why they use them(determinants). A detailed analysis of 81 published studies between 2010 and 2021 informs scholars about the current state of research on managerial tone. Based on a signalling framework, this thesis examines the following questions: Does managerial tone have a signalling role? Does the signal (tone) match the latent information it intends to convey? Can the receiver(analysts) correctly interpret the signal and send feedback to confirm(disconfirm) the signal? Does the signalling environment impact signalling effectiveness? How does tone signalling effectiveness varies across signaller’s characteristics? Using a sample of earnings conference call transcripts from FTSE350 firms, empirical tests in this thesis provide evidence that managerial tone can produce effective signals matching the private information from managers. Analysts accurately understand tone signals and send confirmation feedback to managers. The information environment can moderate signalling effectiveness. Beyond this, top managers with a stronger ability and signalling willingness can strengthen tone signalling effectiveness, while top managers with less signalling willingness weaken tone signalling effectiveness. The findings suggest that managerial tone represents a reliable signalling device for transmitting latent information about a firm’s quality and future performance and that receivers can correctly understand this signal and develop a consistent interpretation. It implies that managerial tone can be used for two-way communication. Further, prestigious top managers with more ability and signalling willingness are more valuable for firms to improve their signalling process.
On RR Couplings, Singularity Structures and all order $α'$ contact interactions to BPS String Amplitudes
Creators: name: Hatefi, Ehsan
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We evaluate five point world-sheet string theory amplitudes of one transverse scalar field, two world volume gauge fields ( and two transverse scalars, a gauge field) in the presence of a closed string Ramond-Ramond vertex operator in its symmetric picture. We carry out all the entire S-matrix elements of five point mixed RR-scalars/gauge fields $$, $$, $$ and $$ in detail and start comparing all order $α'$ contact interactions and singularities in both transverse and world volume directions. We explore the presence of various new couplings in string theory effective actions and find out their all order $α'$ higher derivative corrections in both type IIA and IIB. Ultimately we make various remarks for the singularities and contact terms whose RR momenta are embedded in transverse directions. $α'$ corrections to some of Myers terms are also addressed.
description: V2:39 pages,no figure, Latex file. The style has been improved, explanations and clarifications are given. The accepted version in JHEP
Ribosomal S6 kinase 2 directly phosphorylates the 5-hydroxytryptamine 2A (5-HT2A) serotonin receptor, thereby modulating 5-HT2A signaling
Creators: name:  Sheffler, D.J.
name:  Willard, B.
name: Strachan, R.T.
name:  Kiselar, J.G.
name:  Roth, B.L.
name:  Kinter, M.
Publisher: name: American Society for Biochemistry and Molecular Biology Inc.
Year: 2009

description: The 5-hydroxytryptamine 2A (5-HT2A) receptor is a member of the G protein-coupled receptor superfamily (GPCR) and plays a key role in transducing a variety of cellular signals elicited by 5-hydroxytryptamine in both peripheral and central tissues. Despite its broad physiological importance, our current understanding of 5-HT2A receptor regulation is incomplete.We recently reported the novel finding that the multifunctional ERK effector ribosomal S6 kinase 2 (RSK2) physically interacts with the 5-HT2A receptor third intracellular (i3) loop and modulates receptor signaling (Sheffler, D. J., Kroeze, W. K., Garcia, B. G., Deutch, A. Y., Hufeisen, S. J., Leahy, P., Bruning, J. C., and Roth, B. L. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 4717-4722). We report here that RSK2 directly phosphorylates the 5-HT2A receptor i3 loop at the conserved residue Ser-314, thereby modulating 5-HT2A receptor signaling. Furthermore, these studies led to the discovery that RSK2 is required for epidermal growth factor-mediated heterologous desensitization of the 5-HT2A receptor. We arrived at these conclusions via multiple lines of evidence, including in vitro kinase experiments, tandem mass spectrometry, and site-directed mutagenesis. Our findings were further validated using phospho-specific Western blot analysis, metabolic labeling studies, and whole-cell signaling experiments. These results support a novel regulatory mechanism in which a downstream effector of the ERK/MAPK pathway directly interacts with, phosphorylates, and modulates signaling of the 5-HT2A serotonin receptor. To our knowledge, these findings are the first to demonstrate that a downstream member of the ERK/MAPK cascade phosphorylates a GPCR as well as mediates cross-talk between a growth factor and a GPCR.
ENHANCING NURSE KNOWLEDGE REGARDING INCONTINENCE TO PREVENT HOSPITAL ACQUIRED PRESSURE INJURIES
Creators: name: Arellano, Emily S.
Publisher: name: Zenodo
Year: 2023
Subjects: incontinence
incontinence associated dermatitis
hospital acquired pressure injuries
incontinence associated dermatitis education
evidence-based practice guidelines
risk factors

description: Incontinence associated dermatitis (IAD) is a skin condition that occurs from prolonged exposure to urinary or fecal incontinence. Prevalence of IAD in the acute setting ranges from 18-95% and contributes to inflammation, pain, and increases risk of developing hospital acquired pressure injuries (HAPIs). There are deviations in evidence-based practice and management among healthcare professionals leading to misdiagnosis, improper IAD treatment, and HAPI development. This doctoral project examines the impact of enhancing nursing knowledge of IAD to reduce HAPIs using a pre- and post-implementation design. A convenience sample of 45 nurses, on a 34-bed Progressive Care Unit at an acute care facility in Southern California, participated in an IAD educational module to assess a change in nursing knowledge. The IAD education used two validated tools the Ghent Global IAD categorization tool (GLOBAID) and Knowledge Instrument on Incontinence-Associated Dermatitis for Clinicians (KNOW-IAD) to measure IAD etiology, classification, and management knowledge. Monthly and quarterly surveillance data of HAPI occurrence and incontinence incidence were collected. Participant scores resulted in an overall increase in nurse IAD knowledge while concurrently decreasing HAPIs with 62.5% of patients having incontinence (p < .001). Zero monthly HAPI’s were noted four of the five months post-implementation, as well as on the next two consecutive prevalence studies. Expanding the education hospital wide and providing education annually will increase generalizability and streamline the implementation of IAD education. Nurse-driven IAD educational modules are effective in improving nursing knowledge of IAD and aid in reducing HAPI incidence.
title: CT-guided percutaneous transthoracic core biopsy (PTCB) of deep thoracic lesions using pure virtual navigation guidance (PVNG) with magnetic-tracking system: preliminary experiences
Creators: name: Bizzarri, Giancarlo
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Interventional non-vascular
subject: Lung
subject: Oncology
subject: CT
subject: PET-CT
subject: Image manipulation / Reconstruction
subject: Biopsy
subject: Perception image
subject: Instrumentation
subject: Image registration
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: CT-guided PTCB is essential for the differential diagnosis between benign and malignant pulmonary and mediastinal tumors and for cellular characterization by somatic mutation and cellular differentiation analysis. Cellular characterization is...
Stop It, and Be Stubborn!
Creators: name: Valmari, Antti
Publisher: name: arXiv
Year: 2015
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences
subject: D.2.4; F.3.1
subject: 68Q60, 68Q85, 68N30

description: A system is AG EF terminating, if and only if from every reachable state, a terminal state is reachable. This publication argues that it is beneficial for both catching non-progress errors and stubborn set state space reduction to try to make verification models AG EF terminating. An incorrect mutual exclusion algorithm is used as an example. The error does not manifest itself, unless the first action of the customers is modelled differently from other actions. An appropriate method is to add an alternative first action that models the customer stopping for good. This method typically makes the model AG EF terminating. If the model is AG EF terminating, then the basic strong stubborn set method preserves safety and some progress properties without any additional condition for solving the ignoring problem. Furthermore, whether the model is AG EF terminating can be checked efficiently from the reduced state space.
title: The optimisation of magnetic resonance imaging pulse sequences in order to better detection of multiple sclerosis plaques
Creators: name: Abdolmohammadi, Jamil
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: CNS
subject: Neuroradiology brain
subject: CNS
subject: MR
subject: Diagnostic procedure
subject: Imaging sequences
subject: Demineralisation-Bone
subject: Inflammation
subject: Cerebrospinal fluid

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: MS is an inflammatory demyelinating disease of the central nervous system (CNS). It is the most common demyelinating disease after vascular- and age-related demyelination. MS is characterized by multiple “plaques” of demyelination in the white...
(103365) Lucy Tricks
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Associations among cognitive functions, plasma DNA, and white matter integrity in patients with early-onset Parkinson’s disease
Creators: name: Chen, Yueh-Sheng
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: CNS
subject: Neuroradiology brain
subject: MR-Diffusion/Perfusion
subject: Comparative studies

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Parkinson’s disease (PD) is one of the most common neurodegenerative diseases worldwide [1]. Although PD mainly affects older patients, with a mean age of onset at around 60 years old, some patients develop it at a relatively early age...
A chemical-genetic approach to study G protein regulation of β cell function in vivo
Creators: name: Ma, X.
name: Scarselli, M.
name: Li, J.H.
name: Guettier, J.-M.
name: Wess, J.
name: Rosemond, E.
name: Roth, B.L.
name: Gonzalez, F.J.
name: Armbruster, B.N.
name: De Azua, I.R.
name: Gautam, D.
name: Lu, H.
Publisher: name: National Academy of Sciences
Year: 2009

description: Impaired functioning of pancreatic β cells is a key hallmark of type 2 diabetes. β cell function is modulated by the actions of different classes of heterotrimeric G proteins. The functional consequences of activating specific β cell G protein signaling pathways in vivo are not well understood at present, primarily due to the fact that β cell G protein-coupled receptors (GPCRs) are also expressed by many other tissues. To circumvent these difficulties, we developed a chemicalgenetic approach that allows for the conditional and selective activation of specific β cell G proteins in intact animals. Specifically, we created two lines of transgenic mice each of which expressed a specific designer GPCR in β cells only. Importantly, the two designer receptors differed in their G protein-coupling properties (Gq/11 versus Gs). They were unable to bind endogenous ligand(s), but could be efficiently activated by an otherwise pharmacologically inert compound (clozapine-N-oxide), leading to the conditional activation of either β cell Gq/11 or Gs G proteins. Here we report the findings that conditional and selective activation of β cell Gq/11 signaling in vivo leads to striking increases in both first- and second-phase insulin release, greatly improved glucose tolerance in obese, insulin-resistant mice, and elevated β cell mass, associated with pathway-specific alterations in islet gene expression levels. Selective stimulation of β cell Gs triggered qualitatively similar in vivo metabolic effects. Thus, this developed chemical-genetic strategy represents a powerful approach to study G protein regulation of β cell function in vivo.
(103366) Ada Mary Tricks
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
USING AN ELECTRONIC APPLICATION FOR MANAGEMENT OF CHILDREN WITH OBESITY IN PRIMARY CARE
Creators: name: Aldalur, Maydole Lopez
Publisher: name: Zenodo
Year: 2023
Subjects: Children
obesity
weight management

description: Background: Obesity affects one in five children and adolescents in the United States (CDC, 2022). Children who suffer from chronic obesity are at a higher risk of becoming adults with obesity. Chronic obesity in children is associated with comorbidities such as metabolic diseases, heart disease, bullying, and low self-esteem. Current clinical weight management strategies are designed to promote the consumption of fruits and vegetables while increasing active play to reduce obesity rates among children. The development of technology has increased the number of electronic applications geared toward managing adults’ wellness. Children have grown up with technology and can use it with ease. The literature is limited as to the use of electronic applications as tools in weight management for children to track their healthy behaviors. Purpose: Assess the effect of implementing an electronic application geared to school-age children for weight management. Methods: Participants were children from 10–12-year-olds without co-morbidities. Participant variables measured included body weight, BMI, BMI%, waist circumference, self-esteem, intake of fruits, vegetables, and water, and electronic application use. Results: 14 of the 18 participants completed the project. There was an increase in body weight and BMI with a decrease in waist circumference. The self-esteem scores were stable throughout the project. Overall, there was an increase in fruit and vegetable intake. Daily exercise minutes increased post-intervention among all participants. Conclusion: The project’s Start Simple with MyPlate (SSMP) electronic application for weight management successfully decreased waist circumference, which may have been an indication of visceral fat loss.
Resonance in the nonadiabatic quantum pumping of the time-dependent Josephson junction
Creators: name: Zhu, Rui
name: Liu, Mi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In this work, we investigated the nonadiabatic transport properties of the one-dimensional time-dependent superconductor-normal metal-superconductor (SNS) Josephson junction biased by a current source and driven by a high-frequency-ac-gate-potential applied to the normal-metal layer. BCS superconductors are considered and treated with the time-dependent Bogoliubov-de Gennes equation. Using Floquet theory, we compute the transmission coefficients and the Wigner-Smith delay times as a function of the incident energy and find that they display resonances when one of the electron or hole Floquet wavevectors coincides with the bound quasiparticle state within the superconducting energy gap. The resonance varies with the phase difference between the two superconductors as a result of the bound quasiparticle level displacement. The supercurrent flowing through the SNS junction is dramatically enhanced by the resonances.
Differential ontogeny of multiple opioid receptors (μ, δ, and κ)
Creators: name: Spain, J.W.
name: Roth, B.L.
name:  Coscia, C.J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1985

description: We investigated the postnatal ontogeny of opioid receptors in rat brain under assay conditions which, when combined with computerized analysis, effectively reflect the developmental profile of high affinity binding to μ, δ, and κ subpopulations. Concentrations of μ sites were assessed with the selective ligand 3H-[D-ala2,mePhe4,gly-ol5]enkephalin (DAGO). The other two sites were analyzed in binding assays with less selective radioligands but in the presence of specific unlabeled ligands which suppress cross-reactivity. We utilized 3H-[D-ala2,D-leu5]enkephalin (DADL) in the presence of 10 nm DAGO to label δ sites and 3H-ethylketocyclazocine (EKC) in the presence of 100 nm DADL + 100 nm [D-ala2,mePhe4,Met(0)ol5]enkepahlin to detect κ receptors. After birth, the density (femtomoles per milligram of wet weight) of μ sites declined for several days and then rose sharply over the next 2 weeks, increasing 2-fold by adulthood. Delta (δ) sites appeared in the second week postnatal and increased more than 8-fold in the next 2 weeks. Levels of κ receptors were relatively low at birth and increased slowly (2-fold, overall). Computerized analyses of binding data revealed that DAGO and DADL were binding to single populations of sites throughout the postnatal period. DAGO and EKC affinities did not fluctuate in this period, whereas DADL affinities were low for the first week and then rose to adult levels. In summary, μ, κ, and δ receptors exhibit differential postnatal developmental profiles. The former two are present at birth, whereas the latter appears in the second week. The postnatal increase for all three sites appear to be preceded by the previously demonstrated emergence of opioid peptides.