cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: 01_0992
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Comparative assessment of female mouse model of Graves' orbitopathy under different environments, accompanied by pro-inflammatory cytokine and T cell responses to thyrotropin hormone receptor antigen
Creators: name: Berchner-Pfannschmidt, Utta
name: Sajad Moshkelgosha
name: Diaz-Cano, Salvador J.
name: Edelmann, Bärbel
name: Gina-Eva Görtz
name: Horstmann, Mareike
name: Noble, Alistair
name: Hansen, Wiebke
name: Eckstein, Anja
name: J Paul Banga
Publisher: name: figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Pathology
subject: 60406 Genetic Immunology

description: We recently described a preclinical model of Graves' orbitopathy (GO), induced by genetic immunization of eukaryotic expression plasmid encoding human TSH-receptor (hTSHR) A-subunit by muscle electroporation in female BALB/c mice. The onset of orbital pathology is characterized by muscle inflammation, adipogenesis and fibrosis. Animal models of autoimmunity are influenced by their environmental exposures. This follow-up study was undertaken to investigate the development of experimental GO in two different locations, run in parallel under comparable housing conditions. Functional antibodies to TSHR were induced in TSHR A-subunit plasmid immunized animals, and antibodies to IGF-1 receptor α subunit were also present, while control animals were negative in both locations. Splenic T cells from TSHR A-subunit primed animals undergoing GO in both locations showed proliferative responses to purified TSHR antigen and secreted IFN-γ, IL-10, IL-6 and TNF-α cytokines. Histopathological evaluation showed orbital tissue damage in mice undergoing GO, manifest by adipogenesis, fibrosis and muscle damage with classic signs of myopathy. Although no inflammatory infiltrate was observed in orbital tissue in either location, the appearances were consistent with a 'hit and run' immune-mediated inflammatory event. A statistically significant increase of cumulative incidence of orbital pathology when compared to control animals was shown for both locations, confirming onset of orbital dysimmune myopathy. Our findings confirm expansion of the model in different environments, accompanied with increased prevalence of T cell derived pro-inflammatory cytokines, with relevance for pathogenesis. Wider availability of the model makes it suitable for mechanistic studies into pathogenesis and undertaking of novel therapeutic approaches.
Singapore's War on Drugs: A Historical Overview
Creators: name: Stephanie Chok,
Publisher: name: National University of Singapore
Year: 2018
Subjects: Singapore
Drugs
Offenders
Penal System
Social Policy
Crime
War on drugs
History

description: Singapore's 'zero tolerance approach' to drugs has been well-established, but there were periods in our history when drug use was viewed as an acceptable social habit, one no more harmful than consuming port or beer; and when opium trading was also extremely profitable. This case study contextualizes Singapore's stance on drugs by providing a historical overview of key shifts in legislative approaches to drug use and trafficking in Singapore, with these milestones both reflecting as well as shaping transitions in moral discourses around what has become unequivocally framed as a 'resilient social problem' capable of destroying the lives of responsible citizens, their families, and national development imperatives.
A Harm Reduction Approach to HIV/AIDS and Drug Use in Malaysia
Creators: name: Jade Goh,
Publisher: name: National University of Singapore
Year: 2018
Subjects: Malaysia
HIV
AIDS
Social Policy
Drugs
Health
Public Health

description: In 2006, the Malaysian government introduced harm reduction as a strategy to address the growing HIV/AIDS epidemic among injecting drug users (IDUs) in Malaysia. The country's harm reduction approach comprised of two initiatives: methadone maintece therapy and the needle syringe exchange program. The introduction of harm reduction marked the government's shifting attitude from one that viewed drugs as a national security issue towards one that treated drugs as a public health concern. But Malaysia's harm reduction initiatives still faced numerous challenges. Such strategies were viewed as being counter to the Islamic laws of prohibition and thus faced opposition from some religious leaders and organizations. Further, the public generally took a negative view of IDUs, and law enforcement agencies and public health initiatives sometimes came into tension. The challenges involved in scaling harm reduction efforts had wider implications for the treatment and rehabilitation of drug dependents in Malaysia.
Singapore's Smart Nation Initiative - A Policy and Organisational Perspective
Creators: name: Woo Jun Jie,
Publisher: name: National University of Singapore
Year: 2017
Subjects: Singapore
Smart Nation
Digitialisation
Knowledged-based
Digital transformation
Urbanisation
e-government
Digital Government

description: In light of an increasingly digitised and knowledge-based economy, Singapore introduced its Smart Nation initiative. As a policy initiative guiding Singapore's digital transformation, the Smart Nation initiative relies on several policy tools or 'enablers' to achieve a range of economic, social, and urban policy goals. This case study will assess these policy tools and goals, situating them within the context of Singapore's overall approach to economic development. More than simply a policy initiative, the Smart Nation initiative has also involved public administrative reform. In response to inadequate public interest as well as a perceived lack of pace in Singapore's digital transformation, a centralised public agency, the Smart Nation and Digital Government Group, was formed to coordinate cross-government digitisation efforts. Singapore's ongoing transformation into a Smart Nation has therefore involved both policy innovation and a reorganization of public administration processes. However, Singapore also continues to face challenges in its digitisation efforts, such as insufficient private sector participation or ground-up initiatives.
Rehabilitation, Recidivism and Reintegration: An Examination of Singapore's Penal System for Drug Offenders
Creators: name: Stephanie Chok,
Publisher: name: National University of Singapore
Year: 2018
Subjects: Singapore
Drugs
Offenders
Penal System
Social Policy
Crime
War on drugs

description: Singapore has the third highest prisoners-per-population rate among advanced economies, due largely to a strict stance on drug-related crimes. An earlier case study detailed the evolution of Singapore's 'war on drugs'. The case study begins with a brief statistical overview of Singapore's prison population, with an emphasis on drug offenders. This case study will also give an introduction to the Singapore Prison Service (SPS) and its key partners, as well as their incarceration, rehabilitation, and reintegration frameworks. It includes a discussion on a distinctive feature of halfway care in Singapore: the heavy involvement of religious groups and community organizations. The final section discusses prisoner reentry, where state concern is focused on preventing reoffending and successful 'reintegration', of which a core aspect relates to the employment of ex-offenders.
Policy Analysis: Tapping into the Wisdom of the Cybersecurity Crowd
Creators: name: Lim Wei Chieh,
Publisher: name: National University of Singapore
Year: 2017
Subjects: Cybersecurity
Hacking
malware
Singapore
USA
Security
Internet

description: In May 2017, Warren Buffet called cyberattacks "the number one problem with mankind". Cyberattacks are occurring with alarming frequency, sophistication, and scale. The credit reporting company Equifax disclosed in September 2017 that hackers had stolen the personal information of about 143 million United States consumers by exploiting a website vulnerability. Earlier that year, the WannaCry and NotPetya ransomware used a tool stolen from the NSA to attack hundreds of thousands of vulnerable machines and hold them hostage. These attacks had in common the exploitation of software vulnerabilities by cybercriminals. According to the CERT Coordination Center (CERT/CC) of Carnegie Mellon University's Software Engineering Institute (SEI), over 90 percent of reported security incidents are the result of exploits against software design or coding defects. Determining the best way to tackle software vulnerabilities is an ongoing challenge. I argue in this policy analysis that a focus on eliminating or reducing software vulnerabilities is a key pillar in the fight against cybercrime, and that engaging the community of independent white hats in this undertaking provides the highest chance of success.
Policy Analysis: Bridging the Cybersecurity Divide Between Large Enterprises and SMEs
Creators: name: Lim Wei Chieh,
Publisher: name: National University of Singapore
Year: 2018

description: The Word Economic Forum's 2017 report on digital transformation said that business leaders must undertake five action plans to be digitally ready. One of these steps is to improve cybersecurity, a critical factor in the success and survivability of any digital enterprise. This raises important questions for small and medium enterprises, which have limited resources and budgets. Can they afford the high price of cybersecurity to stay safe and survive? And what about cybersecurity divide between large enterprises that can afford state-of-the-art cyber defences and those that cannot? In this paper, we examine these inequalities and their impact on SMEs, industries, and nations; and the policies needed to ensure that SMEs are adequately secured in cyberspace against the context of Singapore's push for SMEs to capture the growth opportunities in the digital economy.
Nesting ecology of flatback sea turtles of West Alligator Head and Field Island, Kakadu National Park
Creators: name: Vanderlely, Roger
Publisher: name: Charles Darwin University
Year: 1996

description: This study examined the plasticity of life history traits, fecundity, reproductive potential and nesting success or Flatback sea turtles (Natator depressus) at West Alligator Head and Field Island, Kakadu National Park, Northern Territory, Australia. Beaches in the area were assessed to their suitability as successful nesting locations. Comparisons were based on the physical properties or the sand, the nature of the coastal vegetation and the seaward approaches to the beaches. Predation of eggs and mortality of hatchlings at each beach were monitored throughout two nesting seasons to identify the major influence on hatchling survivorship to the water's edge. Mortality of eggs was investigated further by the establishment of a hatchery which ensured that some clutches survived predation. Embryonic development within nests was monitored to assess normal levels of fertilisation and mortality during embryogenesis. The sex ratio of hatchlings was investigated and correlated with ambient sand temperatures. incident global radiation and sand colouration.
คุณลักษณะภาวะผู้นำครูในพื้นที่สามจังหวัดชายแดนภาคใต้
Creators: name: จรุณี แสงหวัง, ธีร หฤทัยธนาสันติ์, ผ่องศรี วาณิชย์ศุภวงศ์, นิเลาะ แวอุเซ็ง
Publisher: name: สำนักวิทยบริการ มหาวิทยาลัยสงขลานครินทร์ วิทยาเขตปัตตานี
Year: 2020
Subjects: ภาวะผู้นำครู, สามจังหวัดชายแดนภาคใต้, teacher leadership, three southern border provinces

description: วารสารวิทยบริการ มหาวิทยาลัยสงขลานครินทร์, 31, 1, 157-170
title: Climate variability and extended range flood forecasting for the Amazon basin
Creators: name: Towner, Jamie
Publisher: name: University of Reading
Year: 2021

description: The aim of this research is to investigate how large-scale climate variability affects flooding in the Amazon basin, using this assessment to demonstrate the potential predictability that these modes can provide to enable earlier warning of impactful floods. To address this a multi-stage approach is adopted; first to understand the gaps and confidence in the state of current knowledge on how climate variability affects both rainfall and river discharge in the Amazon basin, secondly, to understand the skill of global hydrological models for undertaking further assessment, and thirdly to undertake a robust assessment of the impact of climate variability on different flood characteristics while considering different methodological approaches in more detail. An assessment of the robustness in the results of previous studies suggests the need to explore in detail the physical mechanisms leading to flood events on an individual basis. While composite analysis of several floods identified a particular response associated with La Niña conditions, investigation into individual events show it is unknown if the same response would be identified for all events individually. The performance of eight large-scale hydrological models are evaluated for their ability to capture previous peak river flows. The choice of precipitation input is found to be the dominant component of the hydrometeorological modelling chain, with improvement found when ERA5 is the chosen meteorological forcing. Calibration of the Lisflood routing model is identified to have no impact on the ability to capture flood peaks, stressing the need to use an objective function that fits the purpose of the model. Examination of how climate variability impacts flood characteristics in the Amazon basin identified significant changes for both flood magnitude and duration during the negative ENSO phase, particularly in the north-eastern Amazon. This response was not identified for eastern Pacific ENSO events, highlighting how results can differ between ENSO types, while no notable impact or pattern is observed for flood timing. This thesis has provided important information on how climate variability impacts less studied flood characteristics (flood timing and duration) which are associated with important flood types (e.g. early or long floods). Future work should focus on the improvement of climate reanalysis to produce a longer-term dataset consistent with observations to extend climate analysis. This would allow the examination on the impact of climate phases at a more granular scale (e.g. analysing the strength or combination of climate phases)
Closing Loops in the Circular Economy - A Make or Buy Analysis for the Smartphone Industry
Creators: name: Revellio, Ferdinand Paul
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2017
Subjects: subject: Circular Economy
subject: Transaction Cost
subject: Sustainability
subject: Smartphone
subject: Kreislaufwirtschaft
subject: Nachhaltigkeit
subject: Transaktionskosten
classificationCode: 333.7
subject: 333.7

description: Smartphones make intensive use of precious metals and so called conflict minerals in order to reach their high performance in a compact size. In recent times, sustainability challenges related to production, use and disposal of smartphones are increasingly a topic of public debate. Thus, established industry actors and newly emerging firms are driven to engage in more sustainable practices, such as sustainable sourcing of materials, maintenance services or take-back schemes for discarded mobile phones. Many of these latter efforts can be related to the concept of a circular economy (CE). This thesis explores how CE-related value creation architectures (VCAs) in the smartphone industry contribute to slowing and closing resource loops in a CE. In order to analyze these new industry arrangements, transaction cost theory (TCT) is used as a guiding theory for a make-or-buy analysis. Combining TCT with the concept of a CE is a novel research approach that enables the empirical analysis of relationships between focal actors (e.g. manufacturers) and newly emerging loop operators (e.g. recycling firms) in the smartphone industry. Case studies of such VCAs are conducted with case companies drawn from the Innovation Network on Sustainable Smartphones (INaS) at Leuphana Universtity of Lüneburg and analyzed regarding their involved actors, partnerships, circular activities, motivation and perceived barriers. Evidence from the conducted case studies suggests that asset specificity for circular practices increases for higher order CE-loops such as maintenance or reuse, therefore long-term partnerships between focal actors and loop operators or vertical integration of CE practices are beneficial strategies to reach a sophisticated CE. Similarly, circular practices that go beyond recycling require a strong motivation, either through integration in the focal firm´s quality commitment or through business model recognition. It is further suggested that the circular design of products and services could reduce necessary transaction costs and thus overall costs of a circular economy. Four different integration strategies for circular economy practices have been derived from the conducted case studies. These are: 1) vertically integrated loops, 2) cooperative loop-networks, 3) outsourcing to loop operators and 4) independent loop operators. This work thus provides evidence that circular economy activities do not necessarily have to be managed by focal actors in the value chain. Rather, circular practices can also be put forward by specialized loop operators or even independent actors such as repair shops.
title: Die Verwendung von Pflanzenkohle im Ackerbau als Bestandteil einer regenerativen Landwirtschaft in Deutschland
title: The Use of Biochar in Crop Farming as a Component of a Regenerative Agriculture in Germany
titleType: AlternativeTitle
Creators: name: Drews-Shambroom, Annika
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2018
Subjects: subject: Agriculture
subject: Pflanzenkohle
subject: Ackerbau
subject: Landwirtschaft
subject: Regeneration
classificationCode: 630
subject: 630 Landwirtschaft und verwandte Bereiche

description: Die heutige industrielle Landwirtschaft birgt vielfältige Probleme wie die Degradierung der Böden, den Verlust von Biodiversität, Nitrate im Grundwasser sowie die hohe Abhängigkeit von fossilen Energieträgern. Einen möglichen Lösungsansatz bietet das Konzept der regenerativen Landwirtschaft, welches weltweit zunehmend Beachtung findet. Deren Ziel ist es, Agrarökosysteme und insbesondere die Böden kontinuierlich zu verbessern, indem durch bestimmte landwirtschaftliche Methoden und ganzheitliches Management unter anderem gestörte Nährstoff-, Wasser- und Kohlenstoff- Kreisläufe wieder geschlossen werden. Die Verwendung von Pflanzenkohle als Bodenhilfsstoff könnte ein mögliches Werkzeug der regenerativen Landwirtschaft sein, da Forschungen gezeigt haben, dass Pflanzenkohle durch ihre spezifischen Eigenschaften in der Lage ist, die physikalischen und chemischen Eigenschaften des Bodens langfristig zu beeinflussen und dadurch zum Bodenaufbau beizutragen. Es handelt sich jedoch um eine vergleichsweise neue Methode, die in Deutschland bislang wenig praktiziert wird, und es gibt einige Kritik an der Produktion und Verwendung von Pflanzenkohle. Das Ziel der Arbeit ist es daher herauszufinden, ob und auf welche Weise die Verwendung von Pflanzenkohle im Ackerbau ein Bestandteil einer regenerativen Landwirtschaft in Deutschland sein kann. Hierfür wurden auf Grundlage der vorhandenen Literatur einige Thesen aufgestellt. Für die empirische Erhebung von Praxiswissen wurden leitfadengestützte Experteninterviews mit je einem Vertreter der Anbauweisen biologisch-dynamisch, organisch-biologisch und der Permakultur geführt. Die Ergebnisse wurden ergänzt durch ein Interview mit einer Expertin aus dem Bereich der Pflanzenkohleproduktion, um technische Details zu konkretisieren. Im Ergebnis wird unter anderem deutlich, dass der Pflanzenkohleeinsatz für jede Fläche gründlich überlegt werden muss. Allgemein sollte Pflanzenkohle nur in kleinen, dezentralen landwirtschaftlichen Systemen eingesetzt werden und Teil einer Abfall-Management-Strategie sein. Es müssen sowohl das Ziel der Anwendung, als auch die Eigenschaften der eingesetzten Kohle bekannt sein und ein Einsatz sollte nur in einem System erfolgen, welches bereits regenerativ bewirtschaftet wird.
title: Evidenzbasierte Entwicklung von Unterricht und Schule im Kontext neuer Steuerung
title: Evidence-based improvement of instruction and schools in the context of new public management
titleType: AlternativeTitle
Creators: name: Pietsch, Marcus
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2019
Subjects: subject: School Improvement
subject: Lebensnaher Unterricht
subject: Schulentwicklung
classificationCode: 370
subject: 370 Bildung und Erziehung

description: Since the turn of the millenium German schools should be managed by evidence. In this regard, feedback on all levels of the education system plays a central role. Not much is known about how, or even if, those newly introduced measures work. Thus, the present thesis adresses the questions, if an evidence-based improvement of instruction and schools could be successful, how to examine putatitve effects and which mechanisms and context factors are relevant, when it comes to observed effects.
description: Seit der Jahrtausendwende sollen Schulen in Deutschland evidenzbasiert gesteuert werden. Eine wichtige Rolle spielt dabei die Rückmeldung von Informationen auf verschiedenen Ebenen des Schulsystems. Darüber, ob und wie entsprechende Maßnahmen wirken, ist bislang jedoch nur wenig bekannt. Die vorliegende Arbeit beschäftigt sich daher mit den Fragen, ob eine evidenzbasierte Schul- und Unterrichtsentwicklung im Kontext Neuer Steuerung gelingen kann, wie Wirkungen systematisch evaluiert werden können und welche Mechanismen und Kontextbedingungen dafür verantwortlich sein können, dass Wirkungen zu beobachten sind oder nicht.
Pathways to Impact - Written Evidence #1 [LBCO224] Life beyond COVID. UK COVID-19 Committee.
Creators: name: Marston, Hannah
name: Ko, Pei-Chun
name: Ivan, Loredana
name: Silva, Paula Alexandra
Publisher: name: The Open University
Year: 2022
Subjects: Rural sociology
Social change
Sociology and social studies of science and technology
Sociology of health
Sociology of the life course
Urban sociology and community studies
Other built environment and design not elsewhere classified
Community planning
Urban design
Urban informatics

description: A piece of written evidence submitted to the UK COVID-19 Committee in 2020.
 The Covid-19 pandemic has highlighted the importance of digital technology in the lives of citizens, both old and young. This evidence includes the following areas: Use of digital technologies in the community context Citizens who are ageing-without-children Use of videogames in the context of PTSD Using and deploying digital technologies in the context of intergenerational, social isolation and loneliness Introduction to the COVID-19: Technology, Social Connections, Loneliness and Leisure Activities Project ‘Smart Age-friendly Ecosystem’ for the future
Articles on plant elicitors published in Phytoma (1990-2007)
Creators: name: Blanchard, Antoine
Publisher: name: figshare
Year: 2016
Subjects: subject: 60704 Plant Pathology
subject: FOS: Biological sciences
subject: 99901 Agricultural Engineering
subject: FOS: Other engineering and technologies

description: Articles on plant elicitors published in the French professional magazine Phytoma between 1990 and 2007, out of an average of 121 articles per year.
Head Nurses' Support and Registered Nurses' Preparation for the Advancement of Career Ladder as Perceived by Registered Nurses in Secondary and Tertiary Hospitals in the Three Southernmost Provinces
Creators: name: Sasiprapa Artnarong, Sasithorn Laimek
Publisher: name: สำนักวิทยบริการ มหาวิทยาลัยสงขลานครินทร์ วิทยาเขตปัตตานี
Year: 2020
Subjects: support of head nurses, tertiary hospital, registered nurses' career ladder

description: วารสารวิทยบริการ มหาวิทยาลัยสงขลานครินทร์, 31, 1, 171-179
ประสบการณ์นักศึกษาพยาบาลในการพยาบาลข้ามวัฒนธรรมในรายวิชาปฏิบัติการผดุงครรภ์
Creators: name: ปรียา แก้วพิมล
Publisher: name: สำนักวิทยบริการ มหาวิทยาลัยสงขลานครินทร์ วิทยาเขตปัตตานี
Year: 2020
Subjects: นักศึกษาพยาบาล, การพยาบาลข้ามวัฒนธรรม, ปฏิบัติการผดุงครรภ์, student nurse, transcultural nursing, midwifery practicum

description: วารสารวิทยบริการ มหาวิทยาลัยสงขลานครินทร์, 31, 1, 180-196
A systematic review of the safety of incretin-based therapies in type 2 diabetes
Creators: name: Evans, Marc
name: Bain, Stephen C.
name: Jiten Vora
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Introduction: Large randomized clinical trials have demonstrated that incretin-based therapies provide effective glycemic control in type 2 diabetes. Long-term safety assessments are ongoing. Methods: This systematic review of incretin-based therapy safety is based on 112 randomized clinical trials of duration ≥26 weeks published between January 2000 and February 2015 in patients with type 2 diabetes. Results: As expected, hypoglycemia rates were lower with dipeptidyl peptidase-4 inhibitors (DPP-4is) and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) versus other oral antidiabetic drugs and insulin. The most common adverse events were infection and infestation (DPP-4is) and gastrointestinal (GLP-1 RAs). Pancreatitis cases were rare across all studies and, in the SAVOR-TIMI and EXAMINE trials, pancreatitis rates were similar in DPP-4i- and placebo-treated patients. No thyroid tumors were reported, and increased risk of cardiovascular events was not associated with DPP-4is in SAVOR-TIMI and EXAMINE, albeit over a short follow-up period. Conclusions: Overall, incretin-based therapies were well tolerated; however, their long-term safety profile should continue to be periodically assessed.
Tocilizumab and pregnancy: Four cases of pregnancy in young women with rheumatoid arthritis refractory to anti-TNF biologics with exposure to tocilizumab
Creators: name: Kaneko, Kayoko
name: Sugitani, Maki
name: Goto, Mikako
name: Murashima, Atsuko
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Science Policy

description: Objectives: To investigate the use of tocilizumab (TCZ) in pregnant patients with active rheumatoid arthritis (RA) refractory to anti-tumour necrosis factor (TNF) agents. Methods: We retrospectively analysed the medical records of pregnant women with active RA treated between July 2008 and January 2015 by the Division of Maternal Medicine at our hospital. Inclusion criteria for this case series included active RA refractory to anti-TNF agents and exposure to TCZ at the time of conception. Results: Our review of 28 patient hospital records identified four patients who met the inclusion criteria. All four patients had active synovitis before starting treatment with TCZ. Successful TCZ therapy allowed them to plan to become pregnant. When pregnancy was confirmed, TCZ was terminated as soon as possible in all patients. Three patients delivered full-term infants without any adverse outcomes. One patient had a partial molar pregnancy and miscarried during gestational week 11. Two patients remained in clinical remission with low-dose prednisolone (PSL) or no treatment for RA during pregnancy. Conclusions: TCZ may be a good alternative therapy for RA patients with symptoms that are hard to control with TNF blockers who desire to bear children.
ปฏิบัติการพยาบาลข้ามวัฒนธรรมในรายวิชาปฏิบัติการพยาบาลมารดาและทารกแรกเกิดของนักศึกษาคณะพยาบาลศาสตร์
Creators: name: ฉมาพร หนูเพชร, ปรียา แก้วพิมล
Publisher: name: สำนักวิทยบริการ มหาวิทยาลัยสงขลานครินทร์ วิทยาเขตปัตตานี
Year: 2020
Subjects: การพยาบาลข้ามวัฒนธรรม, การพยาบาลมารดาและทารกแรกเกิด, นักศึกษาพยาบาล, transcultural nursing, maternal and newborn nursing, nursing students

description: วารสารวิทยบริการ มหาวิทยาลัยสงขลานครินทร์, 31, 1, 197-208
Are opinion leaders better represented?
Creators: name: Lloren, Anouk
name: Wüest, Reto
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Few studies have analysed the effect of political engagement on legislators’ responsiveness. This article focuses on opinion leaders defined as citizens who regularly discuss politics and who attempt to persuade others to change their viewpoint. It investigates whether opinion leaders are better represented compared to other voters. Taking advantage of the Swiss institution of direct democracy, the article combines roll-call votes and information from popular votes to compare the voting behaviour of legislators and citizens on exactly the same policy proposals. It thus overcomes limitations pertaining to the lack of identical information on elites’ and citizens’ preferences that is common in the literature. The findings show that opinion leaders are better represented than the rest of the electorate in those instances where both sub-groups disagree, and that issue salience does not increase responsiveness to rank-and-file voters. These findings have important implications for understanding unequal representation.
title: 02_1817
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
title: 01_2791
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Impact of a flood event on the zooplankton of an estuarine lake
Creators: name: Jones, Salome
name: Perissinotto, Renzo
name: Carrasco, Nicola Kim
name: Vosloo, Andre
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Shallow coastal lakes are prone to large fluctuations in physico-chemical variables such as salinity and turbidity. This is now escalating in response to global change. A flood event in March 2014 resulted in a silt plume spreading through part of Lake St Lucia (South Africa). To determine the impact of this event on zooplankton, the Narrows region of St Lucia was sampled on a monthly basis from March to September 2014. For comparative purposes, data from samples collected prior to the flood event were included in the analyses. Analysis of similarity (ANOSIM) revealed dissimilarities in zooplankton community structure among the sampling occasions. The March 2014–May 2014 period was characterized by the highest abundance of freshwater species. Conversely, the abundance of the resident St Lucia copepods Acartiella natalensis and Oithona brevicornis was lowest during this time, and highest in September 2014. The other dominant copepod Pseudodiaptomus stuhlmanni prevailed in March 2014, but declined markedly in April. As of September 2014, P. stuhlmanni had yet to regain its pre-flood densities. The BIOENV procedure, which relates biological and environmental data, revealed that turbidity, salinity and dissolved oxygen were responsible for the observed changes in zooplankton community structure during the study period. Careful management of turbidity and salinity is stressed, as both factors are major drivers of the biota of St Lucia and similar systems worldwide.
Institutional Data Use Project - NTU
Creators: name: The Centre For Transforming Access And Student Outcomes In Higher Education (TASO)
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Education
subject: Social and Behavioral Sciences

description: This is a pre-registration of an analysis protocol to test the effectiveness of Nottingham Trent University's Black Leadership programme using a quasi-experimental design.
Impact of endo- and exogenous estrogens on heart rate variability in women: a review
Creators: name: J. J. Von Holzen
name: G. Capaldo
name: M. Wilhelm
name: P. Stute
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Measurement of heart rate variability (HRV) is an established method to assess the activity of the autonomic nervous system. The aim of this review was to examine the link between HRV, reproductive life stages and menopausal hormone therapy. A literature review was performed using the Medline database. Based on title and abstract, 45 studies were extracted out of 261 citations screened. Due to different study designs and evaluation methods, HRV indices were not directly comparable. Qualitative comparisons in between the vast majority of studies, however, demonstrated a decrease of the vagal dominance on the heart from the follicular to the luteal cycle phase, although some studies asserted no change. The intake of oral contraceptives appeared not to alter the vagal modulation of the heart. All investigations agreed on a decline of HRV towards higher sympathetic control after menopause. Different menopausal hormone therapy approaches showed a supporting impact of estrogen on HRV in most studies. A combined therapy of estrogen and progestogens revoked this benefit. Further research is needed to demonstrate how this process might be attenuated by different menopausal hormone therapies.
Manufacture of a MoO3 coated copper made device
Creators: name: Macis, Salvatore
name: D'Elia, Alessandro
name: Mosesso, Luca
name: Rzevani, Javid
name: Spataro, Bruno
name: Lupi, Stefano
name: Marcelli, Augusto
Publisher: name: INFN Open Access Repository
Year: 2023
Subjects: accelerating cavities;
molybdenum coatings;
RF breakdown;
high brightness accelerators

description: We describe the procedure to manufacture a model of a cylindrical RF cavity made in copper and coated with a 100 nm thick layer of molybdenum trioxide. The device is 100 mm long, has an internal diameter of 60 mm and an external diameter of 80 mm. The cylindrical device was carefully divided into four sections to make possible the coating on the internal curved surfaces polished to a roughness < 10 nm. The molybdenum trioxide has been deposed utilizing a thermal evaporation technique with a dedicated high vacuum chamber equipped with a high-temperature Alumina crucible working in the temperature range of 400° - 600° C.
title: 01_0897
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Tocilizumab and pregnancy: four cases of pregnancy in young women with rheumatoid arthritis refractory to anti-TNF biologics with exposure to tocilizumab
Creators: name: Kaneko, Kayoko
name: Sugitani, Maki
name: Goto, Mikako
name: Murashima, Atsuko
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Science Policy

description: Objectives To investigate the use of tocilizumab (TCZ) in pregnant patients with active rheumatoid arthritis (RA) refractory to anti-tumour necrosis factor (TNF) agents. Methods We retrospectively analysed the medical records of pregnant women with active RA treated between July 2008 and January 2015 by the Division of Maternal Medicine at our hospital. Inclusion criteria for this case series included active RA refractory to anti-TNF agents and exposure to TCZ at the time of conception. Results Our review of 28 patient hospital records identified 4 patients who met the inclusion criteria. All 4 patients had active synovitis before starting treatment with TCZ. Successful TCZ therapy allowed them to plan to become pregnant. When pregnancy was confirmed, TCZ was terminated as soon as possible in all patients. Three patients delivered full-term infants without any adverse outcomes. One patient had a partial molar pregnancy and miscarried during gestational week 11. Two patients remained in clinical remission with low- dose prednisolone or no treatment for RA during pregnancy. Conclusions TCZ may be a good alternative therapy for RA patients with symptoms that are hard to control with TNF blockers who desire to bear children.
Album. Corfou. Tupper, William Vaughn scrapbook collection. Volume 14, circa 1891–1895 (en). Άλμπουμ. Κέρκυρα. Tupper, William Vaughn λεύκωμα συλλογή. Τόμος 14, περίπου 1891-1895 (ελ). Álmpoum. Kérkyra. Tupper, William Vaughn leúkōma syllogḗ. Tómos 14, perípou 1891-1895 (el)
Creators: name: Tupper, William Vaughn
Publisher: name: Zenodo
Year: 2020
Subjects: subject: Κέρκυρα
subject: Ιόνια Νησιά
subject: Περιφέρεια Δυτικής Ελλάδας
subject: Φωτογραφικό Λεύκωμα
subject: Corfu
subject: Kerkyra
subject: Ionian Islands
subject: Western Greece Region
subject: Hellas
subject: Greece
subject: Europe
subject: http://id.worldcat.org/fast/1240964
subject: http://id.worldcat.org/fast/1061595
subject: https://www.latlong.net/c/?lat=39.621841&long=19.917959

description: Φωτογραφικό άλμπουμ του Tupper, William Vaughn κατά τη διάρκεια ταξιδιού στην Κέρκυρα περίπου το 1891-1895.
description: Πηγή: Boston Public Library/Print Department Collection No known copyright restrictions. No known restrictions on use.
A method to determine the mode of binding for GCPII inhibitors using bio-layer interferometry
Creators: name: Choy, Cindy J.
name: Berkman, Clifford E.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: The rapid dilution of the enzyme-inhibitor complex assay to monitor the recovery of enzyme activity is a well-established assay to determine the reversibility of inhibition. Our laboratory has previously employed this method to ascertain the reversibility of known glutamate carboxypeptidase II (GCPII)-targeting agents. Due to the tedious and time-consuming nature of the assay, we sought to develop a facile method to determine the reversibility of well-characterized GCPII inhibitors using bio-layer interferometry (BLI). The results from the BLI assay are in agreement with the rapid dilution method. Herein, we report for the first time, a rapid, novel real-time BLI method to determine reversibility of inhibition.
Pharmacophore generation, atom-based 3D-QSAR, HQSAR and activity cliff analyses of benzothiazine and deazaxanthine derivatives as dual A2A antagonists/MAO‑B inhibitors
Creators: name: S. S. Bhayye
name: K. Roy
name: A. Saha
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Dual inhibition of A2A and MAO-B is an emerging strategy in neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). In this study, atom-based three-dimensional quantitative structure–activity relationship (3D-QSAR) and hologram quantitative structure–activity relationship (HQSAR) models were generated with benzothiazine and deazaxanthine derivatives. Based on activity against A2A and MAO-B, two statistically signiﬁcant 3D-QSAR models (r2 = 0.96, q2 = 0.76 and r2 = 0.91, q2 = 0.63) and HQSAR models (r2 = 0.93, q2 = 0.68 and r2 = 0.97, q2 = 0.58) were developed. In an activity cliff analysis, structural outliers were identified by calculating the Mahalanobis distance for a pair of compounds with A2A and MAO-B inhibitory activities. The generated 3D-QSAR and HQSAR models, activity cliff analysis, molecular docking and dynamic studies for dual target protein inhibitors provide key structural scaffolds that serve as building blocks in designing drug-like molecules for neurodegenerative diseases.