cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
CN and HCN in Dense Interstellar Clouds
Creators: name: Boger, Gai I.
name: Sternberg, Amiel
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a theoretical investigation of CN and HCN molecule formation in dense interstellar clouds. We study the gas-phase CN and HCN production efficiencies from the outer photon-dominated regions (PDRs) into the opaque cosmic-ray dominated cores. We calculate the equilibrium densities of CN and HCN, and of the associated species C+, C, and CO, as functions of the far-ultraviolet (FUV) optical depth. We consider isothermal gas at 50 K, with hydrogen particle densities from 10^2 to 10^6 cm^-3. We study clouds that are exposed to FUV fields with intensities 20 to 2*10^5 times the mean interstellar FUV intensity. We assume cosmic-ray H2 ionization rates ranging from 5*10^-17 s^-1, to an enhanced value of 5*10^-16 s^-1. We also examine the sensitivity of the density profiles to the gas-phase sulfur abundance.
description: Accepted for publication in ApJ, 33 pages, 8 figures
Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program
Creators: name: Highland, H.M
name: Vasan, R.S
name: Wu, P
name: Guo, X
name: Goodarzi, M.O
name: Rotter, J.I
name: Mitchell, B.D
name: DiCorpo, D
name: National Heart, Lung, and Blood Institute TOPMed Consortium
name: Leong, A
name: Rich, S.S
name: Porneala, B.C
name: Xu, H
name: Johnson, A.D
name: Raffield, L.M
name: Psaty, B.M
name: TOPMed Diabetes Working Group
name: Reiner, A.P
name: Selvin, E
name: de Vries, P.S
name: O'Connell, J.R
name: Boerwinkle, E
name: Zheng, X
name: Curran, J.E
name: Perry, J.A
name: Wessel, J
name: TOPMed Hemostasis Working Group
name: Dupuis, J
name: Brody, J.A
name: TOPMed Hematology Working Group
name: Liu, C.-T
name: Correa, A.
name: Peralta, J.M
name: Mathias, R
name: Meigs, J.B
name: Cupples, L.A
name: Naik, R.P
name: Hidalgo, B.A
name: Morrison, A.C
name: Liu, Y
name: Sarnowski, C
name: Blangero, J
name: Hu, Y
name: Kooperberg, C
name: Manning, A.K
name: Jain, D
Publisher: name: Cell Press
Year: 2019

description: Hemoglobin A1c (HbA1c) is widely used to diagnose diabetes and assess glycemic control in individuals with diabetes. However, nonglycemic determinants, including genetic variation, may influence how accurately HbA1c reflects underlying glycemia. Analyzing the NHLBI Trans-Omics for Precision Medicine (TOPMed) sequence data in 10,338 individuals from five studies and four ancestries (6,158 Europeans, 3,123 African-Americans, 650 Hispanics, and 407 East Asians), we confirmed five regions associated with HbA1c (GCK in Europeans and African-Americans, HK1 in Europeans and Hispanics, FN3K and/or FN3KRP in Europeans, and G6PD in African-Americans and Hispanics) and we identified an African-ancestry-specific low-frequency variant (rs1039215 in HBG2 and HBE1, minor allele frequency (MAF) = 0.03). The most associated G6PD variant (rs1050828-T, p.Val98Met, MAF = 12% in African-Americans, MAF = 2% in Hispanics) lowered HbA1c (−0.88% in hemizygous males, −0.34% in heterozygous females) and explained 23% of HbA1c variance in African-Americans and 4% in Hispanics. Additionally, we identified a rare distinct G6PD coding variant (rs76723693, p.Leu353Pro, MAF = 0.5%; −0.98% in hemizygous males, −0.46% in heterozygous females) and detected significant association with HbA1c when aggregating rare missense variants in G6PD. We observed similar magnitude and direction of effects for rs1039215 (HBG2) and rs76723693 (G6PD) in the two largest TOPMed African American cohorts, and we replicated the rs76723693 association in the UK Biobank African-ancestry participants. These variants in G6PD and HBG2 were monomorphic in the European and Asian samples. African or Hispanic ancestry individuals carrying G6PD variants may be underdiagnosed for diabetes when screened with HbA1c. Thus, assessment of these variants should be considered for incorporation into precision medicine approaches for diabetes diagnosis.
A Report of Two Cases of Solid Facial Edema in Acne
Creators: name: Kuhn-Régnier, Sarah
name: Mangana, Joanna
name: Kerl, Katrin
name: Kamarachev, Jivko
name: French, Lars E.
name: Cozzio, Antonio
name: Navarini, Alexander A.
Publisher: name: Adis Journals
Year: 2018
Subjects: subject: Medicine
subject: 110304 Dermatology
subject: FOS: Clinical medicine

description: Article full text
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Percolation and Magnetization in the Continuous Spin Ising Model
Creators: name: Bialas, Piotr
name: Blanchard, Philippe
name: Fortunato, Santo
name: Gandolfo, Daniel
name: Satz, Helmut
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: In the strong coupling limit the partition function of SU(2) gauge theory can be reduced to that of the continuous spin Ising model with nearest neighbour pair-interactions. The random cluster representation of the continuous spin Ising model in two dimensions is derived through a Fortuin-Kasteleyn transformation, and the properties of the corresponding cluster distribution are analyzed. It is shown that for this model, the magnetic transition is equivalent to the percolation transition of Fortuin-Kasteleyn clusters, using local bond weights. These results are also illustrated by means of numerical simulations.
Strong decays of exotic and non-exotic heavy baryons in the chiral quark-soliton model
Creators: name: Kim, Hyun-Chul
name: Polyakov, Maxim V.
name: Praszalowicz, Michal
name: Yang, Ghil-Seok
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the large $N_c$ limit both heavy and light baryons are described by the universal mean field, which allows us to relate the properties of heavy baryons to light ones. With the only input from the decays of light octet baryons (due to the universality of the chiral mean field), excellent description of strong decays of both charm and bottom sextets is obtained. The parameter-free prediction for the widths of exotic anti-decapentaplet ($\overline{\boldsymbol{15}}$) baryons is also made. The exotic heavy baryons should be anomalously narrow despite of large phase space available. In particular, the widths of $Ω_c(3050)$ and $Ω_c(3119)$, interpreted as members of $\overline{\boldsymbol{15}}$-plet, are very small: 0.48~MeV and 1.12~MeV respectivly. This result is in very good agreement with the measurements of the LHCb Collaboration and provides natural and parameter free explanation of the LHCb observation that $Ω_c(3050)$ and $Ω_c(3119)$ have anomalously small widths among five recently observed states.
description: 13 pages, 3 figures. Discussion on large Nc limit of the decay couplings added. Acknowledgment added. Version to appear in Physics. Rev. D
Continued lessons from the INS gene: An intronic mutation causing diabetes through a novel mechanism
Creators: name: Greeley, S.A.W
name: Bell, G.I
name: Philipson, L.H
name: Highland, H.M
name: Hanis, C.L
name: Alkorta-Aranburu, G
name: Perrone, M.E
name: Ye, H
name: Park, S.-Y
name: Carmody, D
Publisher: name: BMJ Publishing Group
Year: 2015

description: Background Diabetes in neonates usually has a monogenic aetiology; however, the cause remains unknown in 20-30%. Heterozygous INS mutations represent one of the most common gene causes of neonatal diabetes mellitus. Methods Clinical and functional characterisation of a novel homozygous intronic mutation (c.187+241G>A) in the insulin gene in a child identified through the Monogenic Diabetes Registry (http://monogenicdiabetes. uchicago.edu). Results The proband had insulin-requiring diabetes from birth. Ultrasonography revealed a structurally normal pancreas and C-peptide was undetectable despite readily detectable amylin, suggesting the presence of dysfunctional ß cells. Whole-exome sequencing revealed the novel mutation. In silico analysis predicted a mutant mRNA product resulting from preferential recognition of a newly created splice site. Wild-type and mutant human insulin gene constructs were derived and transiently expressed in INS-1 cells. We confirmed the predicted transcript and found an additional transcript created via an ectopic splice acceptor site. Conclusions Dominant INS mutations cause diabetes via a mutated translational product causing endoplasmic reticulum stress. We describe a novel mechanism of diabetes, without ß cell death, due to creation of two unstable mutant transcripts predicted to undergo nonsense and non-stop-mediated decay, respectively. Our discovery may have broader implications for those with insulin deficiency later in life.
Domain Walls from Anti-de Sitter Spacetime
Creators: name: Lu, H.
name: Pope, C. N.
name: Townsend, P. K.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We examine $(D-2)$-brane solutions in supergravities, showing that they fall into four categories depending on the details of the dilaton coupling. In general they describe domain walls, although in one of the four categories the metric describes anti-de Sitter spacetime. We study this case, and its $S^1$ dimensional reduction to a more conventional domain wall in detail, focussing in particular on the manner in which the unbroken supersymmetry of the anti-de Sitter solution is partially broken by the dimensional reduction to the domain wall.
description: Latex, 13 pages, no figures, introduction revised and references added
Lettre de Jean-François Séguier à Joseph-Dominique Fabre de Saint-Véran,
Creators: name: Séguier, Jean-François
name: Jean-François Séguier
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Antiquités (général)
Bibliographie
Epigraphie

description: [transcription] [Brouillon de lettre de Séguier, non daté] Mon cher Monsieur,

J'ai été bien fâché d'apprendre que vous ayez eu une fâcheuse maladie et qu'elle ait duré si longtemps. Heureusement, vous voilà rétabli. Je m'en réjouis avec vous, ménagez-vous et ne vous livrez pas à la passion de l'étude qui mine sourdement les meilleures constitutions lorsqu'elle n'est pas modérée. Depuis près de six mois je mène une vie languissante qui me permet à peine d'agir et de m'occuper. Le rhume épidémique qui régna ici pendant les premiers mois de cette année m'incommoda extrémement dans le mois de janvier, février et mars : à la suite, il survint de violents accès de sciatique dont je ne suis pas encore entièrement rétabli puisqu'elle m'a laissé des douleurs aux reins et une grande faiblesse aux jambes, qui me permet à peine de me soutenir et de marcher librement. Ce sont les infirmités de mon âge et je ne dois pas m'en plaindre mais les souffrir chrétiennement.

La personne qui vous a communiqué l'inscription du tombeau de Scipion ne sait pas apparemment qu'il y a plus de 160 ans qu'elle est connue. Doni, dont Gori a publié les anciens monuments que ce savant avait recueillis environ l'an 1630, en a rapporté la première partie p. 165 des Inscription. Doniane imprimées à Florence en 1731. Voir comme Doni l'avait eue de Ménétrier qui était à Rome en 1623, comme il paraît d'une de ses lettres du recueil de Peiresc. Ce savant s'appliquait aux médailles et aux anciens monuments.

L. CORNEL. L. F.

SCIPIO. QVAEST

TR. MIL. ET ANNOS

GNATVS XXXIII

MORTVOS. PATER

REGEM ANTIOCO

SVBEGIT

Muratori l'a ensuite redonnée dans la Novus Thesaurus Inscript. page 1802 n° 4 et l'a placée avec raison inter ipurias. Doni la croyait suspecte. Il ne voulut pas le décider suspecta videtur hec inscriptio, sed docti viri judicabunt. [fol. 95 v] Dans cette inscription, on a eu intention de parler du fils de Scipion qui vainquit le roi Antiochus le grand puisqu'on y dit PATER REGEM ANTIOCHum SUBEGIT, le fils de Scipion l'asiatique qui se nommait Lucius Cornelius Lucii filius Publii Nepos, comme la copie de l'inscription que vous avez reçue de Rome.
description: [personnes citées] Anton Francesco Gori, Claude Ménétrier, Giovanni Battista Doni, Nicolas Claude Fabri seigneur de Peiresc
description: [reférence bibliographique citée] Doni, Giovanni Battista, Inscriptiones antique nunc primum editae notisque illustratae..., Florence, 1731.. Muratori Ludovico, Novus Thesaurus Veterum Inscriptionum, Milan, soc. Palatine, 1738-1743, 4 vol.
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 149_2, fol. 95
description: created: 0000-00-00
Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample
Creators: name: Hu, H
name: Gibbs, R.A
name: Karhade, M
name: Valladares-Salgado, A
name: Arking, D.E
name: Below, J.E
name: Chen, H.-H
name: Huff, C.D
name: De Vries, P.S
name: Hanis, C.L
name: Barbeira, A
name: Im, H.K
name: Morrison, A.C
name: Petty, L.E
name: Parra, E.J
name: Cruz, M
name: Ma, J
name: Grove, M.L
name: Doddapaneni, H
name: Highland, H.M
name: Aguilar, D
name: Gamazon, E.R
name: Munzy, D.M
name: Boerwinkle, E
name: Bell, G.I
Publisher: name: Oxford University Press
Year: 2019

description: Interpretation of genetic association results is difficult because signals often lack biological context. To generate hypotheses of the functional genetic etiology of complex cardiometabolic traits, we estimated the genetically determined component of gene expression from common variants using PrediXcan (1) and determined genes with differential predicted expression by trait. PrediXcan imputes tissue-specific expression levels from genetic variation using variant-level effect on gene expression in transcriptome data. To explore the value of imputed genetically regulated gene expression (GReX) models across different ancestral populations, we evaluated imputed expression levels for predictive accuracy genome-wide in RNA sequence data in samples drawn from European-Ancestry and African-Ancestry populations and identified substantial predictive power using European-derived models in a non-European target population.We then tested the association of GReX on 15 cardiometabolic traits including blood lipid levels, body mass index, height, blood pressure, fasting glucose and insulin, RR interval, fibrinogen level, factor VII level and white blood cell and platelet counts in 15 755 individuals across three ancestry groups, resulting in 20 novel gene-phenotype associations reaching experiment-wide significance across ancestries. In addition, we identified 18 significant novel gene-phenotype associations in our ancestry-specific analyses. Top associations were assessed for additional support via query of S-PrediXcan (2) results derived from publicly available genome-wide association studies summary data. Collectively, these findings illustrate the utility of transcriptome-based imputation models for discovery of cardiometabolic effect genes in a diverse dataset.
Evolution and Explosion of Massive Stars Leading to IIP-IIL SNe with MESA and SNEC
Creators: name: Das, Sanskriti
name: Ray, Alak
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We show how the dense shells of circumstellar gas immediately outside the red supergiants (RSGs) can affect the early optical light curves of Type II-P SNe taking the example of SN 2013ej. The peak in V, R and I bands, decline rate after peak and plateau length are found to be strongly influenced by the dense CSM formed due to enhanced mass loss during the oxygen and silicon burning stage of the progenitor. We find that the required explosion energy for the progenitors with CSM is reduced by almost a factor of 2.
description: 6 pages, 7 figure panels, submitted to the Proceedings of IAU Symposium 331, "SN 1987A, 30 years later - Cosmic Rays and Nuclei from Supernovae and their aftermaths" held at Saint-Gilles-Les-Bains, La Reunion Island, France, 20 - 24 February 2017. eds A. Marcowith et al
Two 2MASS-Selected Young Stellar Clusters: Photometry, Spectroscopy, and the IMF
Creators: name: Leistra, A.
name: Cotera, A. S.
name: Liebert, J.
name: Burton, M.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present near-infrared J, H, and K_s images and K-band spectroscopy of two newly discovered stellar clusters at different stages of evolution. Our spectra suggest the presence of massive YSOs in the heavily embedded cluster in the star-forming region near radio source G353.4-0.4 and an O5-O6V star in the cluster near radio source G305+00.2. We determine a K-band luminosity function (KLF) for both clusters and an initial mass function (IMF) for the cluster near G305+00.2. The derived IMF slope is -1.5 if the KLF is used to derive the IMF and is -0.98 if the color-magnitude diagram and spectra are used. The more reliable CMD-based slope is flatter than the Salpeter value usually found for stellar clusters. We find that using the KLF alone to derive an IMF is likely to produce an overly steep slope in stellar clusters subject to variable extinction.
description: 16 pages, 18 figures, accepted to AJ
Enhanced clustering tendency of Cu-impurities with a number of oxygen vacancies in heavy carbon-loaded TiO2 - the bulk and surface morphologies
Creators: name: Zatsepin, D. A.
name: Boukhvalov, D. W.
name: Kurmaev, E. Z.
name: Zatsepin, A. F.
name: Kim, S. S.
name: Gavrilov, N. V.
name: Zhidkov, I. S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The over threshold carbon-loadings (~50 at.%) of initial TiO2-hosts and posterior Cu-sensitization (~7 at.%) was made using pulsed ion-implantation technique in sequential mode with 1 hour vacuum-idle cycle between sequential stages of embedding. The final Cx-TiO2:Cu samples were qualified using XPS wide-scan elemental analysis, core-levels and valence band mappings. The results obtained were discussed on the theoretic background employing DFT-calculations. The combined XPS and DFT analysis allows to establish and prove the final formula of the synthesized samples as Cx-TiO2:[Cu+][Cu2+] for the bulk and Cx-TiO2:[Cu+][Cu0] for thin-films. It was demonstrated the in the mode of heavy carbon-loadings the remaining majority of neutral C-C bonds (sp3-type) is dominating and only a lack of embedded carbon is fabricating the O-C=O clusters. No valence base-band width altering was established after sequential carbon-copper modification of the atomic structure of initial TiO2-hosts except the dominating majority of Cu 3s states after Cu-sensitization. The crucial role of neutral carbon low-dimensional impurities as the precursors for the new phases growth was shown for Cu-sensitized Cx-TiO2 intermediate-state hosts.
description: 27 pages, 7 figures, accepted to Solid State Sciences
Glas_Wagner_2006
Creators: name: Loup Bernard, Heiko Wagner
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2017

description: Base issue de l'ouvrage de Heiko Wagner : Glasschmuck der Mittel- und Spätlatènezeit am Oberrhein und den angrenzenden Gebieten (= Ausgrabungen und Forschungen. Bd. 1). Greiner, Remshalden 2006, ISBN 3-935383-02-9 (Zugleich: Freiburg (Breisgau), Universität, Dissertation, 1998).
Neonatal diabetes, gallbladder agenesis, duodenal atresia, and intestinal malrotation caused by a novel homozygous mutation in RFX6
Creators: name: Reh, C.S
name: Hanis, C.L
name: Ye, H
name: Daniels, M
name: Greeley, S.A.W
name: Liu, X
name: Paz, V.P
name: Concepcion, J.P
name: Highland, H.M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Recently, bi-allelic mutations in the transcription factor RFX6 were described as the cause of a rare condition characterized by neonatal diabetes with pancreatic and biliary hypoplasia and duodenal/jejunal atresia. A male infant developed severe hyperglycemia (446mg/dL) within 24h of birth. Acute abdominal concerns by day five necessitated exploratory surgery that revealed duodenal atresia, gallbladder agenesis, annular pancreas and intestinal malrotation. He also exhibited chronic diarrhea and feeding intolerance, cholestatic jaundice, and subsequent liver failure. He died of sepsis at four months old while awaiting liver transplantation. The phenotype of neonatal diabetes with intestinal atresia and biliary agenesis clearly pointed to RFX6 as the causative gene; indeed, whole exome sequencing revealed a novel homozygous RFX6 mutation c.779A>C; p.Lys260Thr (K260T). This missense mutation also changes the consensus 5′ splice donor site before intron 7 and is thus predicted to cause disruption in splicing. Both parents, who were not known to be related, were heterozygous carriers. Targeted genetic testing based on consideration of phenotypic features may reveal a cause among the many genes now associated with heterogeneous forms of monogenic neonatal diabetes. Our study demonstrates the feasibility of using modern sequencing technology to identify one such rare cause. Continued research is needed to determine the possible cost-effectiveness of this approach, especially when clear phenotypic clues are absent. Further study of patients with RFX6 mutations should clarify its role in pancreatic, intestinal and enteroendocrine cellular development and explain features such as the diarrhea exhibited in our case.
Clean positive operator valued measures for qubits and similar cases
Creators: name: Kahn, Jonas
Publisher: name: arXiv
Year: 2006
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In a recent paper, Buscemi and al. defined a notion of clean positive operator valued measures (POVMs). We here characterize which POVMs are clean in some class that we call quasi-qubit POVMs, namely POVMs whose elements are all rank-one or full-rank. We give an algorithm to check whether a given quasi-qubit POVM satisfies to this condition. We describe explicitely all the POVMs that are clean for the qubit. On the way we give a sufficient condition for a general POVM to be clean.
description: 15 pages, Much of a sequel to quant-ph/0505095 Rewriting of the article deeply improving (I hope) the presentation. Accepted for publication in Journal of Physics A
Thermal quarkonium physics in the pseudoscalar channel
Creators: name: Burnier, Y.
name: Ding, H. -T.
name: Kaczmarek, O.
name: Kruse, A. -L.
name: Laine, M.
name: Ohno, H.
name: Sandmeyer, H.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The pseudoscalar correlator is an ideal lattice probe for thermal modifications to quarkonium spectra, given that it is not compromised by a contribution from a large transport peak. We construct a perturbative spectral function incorporating resummed thermal effects around the threshold and vacuum asymptotics above the threshold, and compare the corresponding imaginary-time correlators with continuum-extrapolated lattice data for quenched SU(3) at several temperatures. Modest differences are observed, which may originate from non-perturbative mass shifts or renormalization factors, however no resonance peaks are needed for describing the quenched lattice data for charmonium at and above T ~ 1.1Tc ~ 350 MeV. For comparison, in the bottomonium case a good description of the lattice data is obtained with a spectral function containing a single thermally broadened resonance peak.
description: 28 pages. v2: published version
Microcephaly, epilepsy, and neonatal diabetes due to compound heterozygous mutations in IER3IP1: Insights into the natural history of a rare disorder
Creators: name: Greeley, S.A.W
name: Boerwinkle, E
name: Philipson, L.H
name: Tenenbaum-Rakover, Y
name: Ye, H
name: Muzny, D.M
name: Hanis, C.L
name: Bell, G.I
name: Paz, V.P
name: Horovitz, Y
name: Highland, H.M
name: Shalev, S.A
name: Gibbs, R.A
name: Carmody, D
Publisher: name: Blackwell Munksgaard
Year: 2014

description: Neonatal diabetes mellitus is known to have over 20 different monogenic causes. A syndrome of permanent neonatal diabetes along with primary microcephaly with simplified gyral pattern associated with severe infantile epileptic encephalopathy was recently described in two independent reports in which disease-causing homozygous mutations were identified in the immediate early response-3 interacting protein-1 (IER3IP1) gene. We report here an affected male born to a non-consanguineous couple who was noted to have insulin-requiring permanent neonatal diabetes, microcephaly, and generalized seizures. He was also found to have cortical blindness, severe developmental delay and numerous dysmorphic features. He experienced a slow improvement but not abrogation of seizure frequency and severity on numerous anti-epileptic agents. His clinical course was further complicated by recurrent respiratory tract infections and he died at 8years of age. Whole exome sequencing was performed on DNA from the proband and parents. He was found to be a compound heterozygote with two different mutations in IER3IP1: p.Val21Gly (V21G) and a novel frameshift mutation p.Phe27fsSer*25. IER3IP1 is a highly conserved protein with marked expression in the cerebral cortex and in beta cells. This is the first reported case of compound heterozygous mutations within IER3IP1 resulting in neonatal diabetes. The triad of microcephaly, generalized seizures, and permanent neonatal diabetes should prompt screening for mutations in IER3IP1. As mutations in genes such as NEUROD1 and PTF1A could cause a similar phenotype, next-generation sequencing approaches-such as exome sequencing reported here-may be an efficient means of uncovering a diagnosis in future cases.
Additional file 1 of Significance of training, monitoring and assessment of malaria workers in achieving malaria elimination goal of Malaria Elimination Demonstration Project
Creators: name: Rajvanshi, Harsh
name: Nisar, Sekh
name: Bharti, Praveen K.
name: Jayswar, Himanshu
name: Mishra, Ashok K.
name: Sharma, Ravendra K.
name: Saha, Kalyan B.
name: Shukla, Man Mohan
name: Das, Aparup
name: Kaur, Harpreet
name: Wattal, Suman L.
name: Lal, Altaf A.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Annexure S1.
Product Expansions of Conformal Characters
Creators: name: Eholzer, Wolfgang
name: Skoruppa, Nils-Peter
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We describe several infinite series of rational conformal field theories whose conformal characters are modular units, i.e. which are modular functions having no zeros or poles in the upper complex half plane, and which thus possess simple product expansions. We conjecture that certain infinite series of rational models of Casimir W-algebras always have this property. Furthermore, we describe an algorithm which can be used to prove whether a modular function is a modular unit or not.
description: 10 pages, LaTeX2e (+amsfonts, amsopn, amsthm, amsmath), one reference added
Long-Term Outcomes after Midurethral Mesh Sling Surgery for Stress Urinary Incontinence
Creators: name: Wu, J.M
name: Pate, V
name: Dejene, S.Z
name: Jonsson Funk, M
Publisher: name: Lippincott Williams and Wilkins
Year: 2022

description: Objectives: Although midurethral mesh slings are the criterion standard surgical treatment for stress urinary incontinence (SUI), limited data exist regarding long-term outcomes. Thus, our objectives were to evaluate the long-term risk of sling revision and the risk of repeat SUI surgery up to 15 years after the initial sling procedure and to identify predictors of these outcomes. Methods: Using a population-based cohort of commercially insured individuals in the United States, we identified women aged 18 years or older who underwent a sling procedure between 2001 and 2018. For sling revision, we evaluated indications (mesh exposure or urinary retention). We estimated the cumulative risks of sling revision and repeat SUI surgery annually using Kaplan-Meier survival curves and evaluated predictors using Cox proportional hazards models. Results: We identified 334,601 mesh sling surgical procedures. For sling revision, the 10-year and 15-year risks were 6.9% (95% confidence interval [CI], 6.7–7.0) and 7.9% (95% CI, 7.5–8.3), with 48.7% of sling revisions associated with mesh exposure. The 10-year and 15-year risks of repeat SUI surgery were 14.5% (95% CI, 14.2–14.8) and 17.9% (95% CI, 17.3–18.6). Women aged 18–29 years had an elevated risk for both sling revision (hazard ratio, 1.20; 95% CI, 1.15–1.25) and repeat SUI surgery (hazard ratio, 1.30; 95% CI, 1.25–1.37) compared with women 70 years and older. Conclusions: In our study population, the 15-year risk of sling revision was 7.9%, with nearly half of revisions due to mesh exposure. These findings provide critical long-term data to support informed decisions for women and health care providers considering midurethral mesh slings.
title: ADCO, Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Cart. 31 (G 135), 549 folios, f. 0954
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0954, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0954, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Magnetoconductance correction in zinc-blende semiconductor nanowires with spin-orbit coupling
Creators: name: Kammermeier, Michael
name: Wenk, Paul
name: Schliemann, John
name: Heedt, Sebastian
name: Gerster, Thomas
name: Schäpers, Thomas
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the effects of spin-orbit coupling on the magnetoconductivity in diffusive cylindrical semiconductor nanowires. Following up on our former study on tubular semiconductor nanowires, we focus in this paper on nanowire systems where no surface accumulation layer is formed but instead the electron wave function extends over the entire cross section. We take into account the Dresselhaus spin-orbit coupling resulting from a zinc-blende lattice and the Rashba spin-orbit coupling, which is controlled by a lateral gate electrode. The spin relaxation rate due to Dresselhaus spin-orbit coupling is found to depend neither on the spin density component nor on the wire growth direction and is unaffected by the radial boundary. In contrast, the Rashba spin relaxation rate is strongly reduced for a wire radius that is smaller than the spin precession length. The derived model is fitted to the data of magnetoconductance measurements of a heavily doped back-gated InAs nanowire and transport parameters are extracted. At last, we compare our results to previous theoretical and experimental studies and discuss the occurring discrepancies.
description: 11 pages, 5 figures, to be published in Phys. Rev. B
Wave functions for Hamiltonian Lattice Gauge Theory
Creators: name: Beccaria, Matteo
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We study four dimensional SU(2) lattice gauge theory in the Hamiltonian formalism by Green's Function Monte Carlo methods. A trial ground state wave function is introduced to improve the configuration sampling and we discuss the interplay between its complexity and the simulation systematic errors. As a case study, we compare the leading strong coupling approximation and an improved 4 parameters wave function with 1X1 and 1X2 plaquette terms. Our numerical results favors the second option.
description: 14 pages, 8 Encapsulated PostScript figures
Nondifferential Treatment Misclassification Biases Toward the Null? Not a Safe Bet for Active Comparator Studies
Creators: name: Jonsson Funk, M.
name: Su, I.-H.
name: Webster-Clark, M.
name: Ross, R.K.
Publisher: name: NLM (Medline)
Year: 2022

description: Active comparator studies are increasingly common, particularly in pharmacoepidemiology. In such studies, the parameter of interest is a contrast (difference or ratio) in the outcome risks between the treatment of interest and the selected active comparator. While it may appear treatment is dichotomous, treatment is actually polytomous as there are at least 3 levels: no treatment, the treatment of interest, and the active comparator. Because misclassification may occur between any of these groups, independent nondifferential treatment misclassification may not be toward the null (as expected with a dichotomous treatment). In this work, we describe bias from independent nondifferential treatment misclassification in active comparator studies with a focus on misclassification that occurs between each active treatment and no treatment. We derive equations for bias in the estimated outcome risks, risk difference, and risk ratio, and we provide bias correction equations that produce unbiased estimates, in expectation. Using data obtained from US insurance claims data, we present a hypothetical comparative safety study of antibiotic treatment to illustrate factors that influence bias and provide an example probabilistic bias analysis using our derived bias correction equations.
2-D models of layered protoplanetary discs: I. The ring instability
Creators: name: Wunsch, R.
name: Klahr, H.
name: Rozyczka, M.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In this work we use the radiation hydrodynamic code TRAMP to perform a two-dimensional axially symmetric model of the layered disc. Using this model we follow the accumulation of mass in the dead zone due to the radially varying accretion rate. We found a new type of instability which causes the dead zone to split into rings. This "ring instability" works due to the positive feedback between the thickness of the dead zone and the mass accumulation rate. We give an analytical description of this instability, taking into account non-zero thickness of the dead zone and deviations from the Keplerian rotational velocity. The analytical model agrees reasonably well with results of numerical simulations. Finally, we speculate about the possible role of the ring instability in protoplanetary discs and in the formation of planets.
description: 9 pages, 5 figures, accepted for publication in MNRAS
Gate-error analysis in simulations of quantum computers with transmon qubits
Creators: name: Willsch, D.
name: Nocon, M.
name: Jin, F.
name: De Raedt, H.
name: Michielsen, K.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: In the model of gate-based quantum computation, the qubits are controlled by a sequence of quantum gates. In superconducting qubit systems, these gates can be implemented by voltage pulses. The success of implementing a particular gate can be expressed by various metrics such as the average gate fidelity, the diamond distance, and the unitarity. We analyze these metrics of gate pulses for a system of two superconducting transmon qubits coupled by a resonator, a system inspired by the architecture of the IBM Quantum Experience. The metrics are obtained by numerical solution of the time-dependent Schrödinger equation of the transmon system. We find that the metrics reflect systematic errors that are most pronounced for echoed cross-resonance gates, but that none of the studied metrics can reliably predict the performance of a gate when used repeatedly in a quantum algorithm.
Праці Наукового Товариства імені Шевченка. – Том LІ. Економічний збірник, Том. 1.
Creators: name: Shevchenko Scientific Society (НТШ)
Publisher: name: figshare
Year: 2018
Subjects: Economics

description: Праці Наукового Товариства імені Шевченка. – Том LІ. Економічний збірник, Том. 1. – Львів, 2017. – 402 с.
Additional file 2 of Significance of training, monitoring and assessment of malaria workers in achieving malaria elimination goal of Malaria Elimination Demonstration Project
Creators: name: Rajvanshi, Harsh
name: Nisar, Sekh
name: Bharti, Praveen K.
name: Jayswar, Himanshu
name: Mishra, Ashok K.
name: Sharma, Ravendra K.
name: Saha, Kalyan B.
name: Shukla, Man Mohan
name: Das, Aparup
name: Kaur, Harpreet
name: Wattal, Suman L.
name: Lal, Altaf A.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Annexure S2.
Methods for scalable optical quantum computation
Creators: name: Mor, Tal
name: Yoran, Nadav
Publisher: name: arXiv
Year: 2006
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a scalable method for implementing linear optics quantum computation using the ``linked-state'' approach. Our method avoids the two-dimensional spread of errors occurring in the preparation of the linked-state. Consequently, a proof is given for the scalability of this modified linked-state model, and an exact expression for the efficiency of the method is obtained. Moreover, a considerable improvement in the efficiency, relative to the original linked-state method, is achieved. The proposed method is applicable to Nielsen's optical ``cluster-state'' approach as well.
description: 4 pages, 3 figures
Gender Equality Index
Creators: name: INSEAD
Publisher: name: EQUAL4EUROPE H2020 project
Year: 2021

description: This is a resource for any organisations that wish to conduct a quantitative analysis of gender dimensions, addressing faculty staff, administrative staff, researchers and students. In addition, contents included in this table can be used as a guideline to implement and track gender equality indicators. The document also assesses the existence and implementation of gender equality policies, and gender opportunities.
Ionized Gas Kinematics around an Ultra-luminous X-ray Source in NGC 5252 : Additional Evidence for an Off-nuclear AGN
Creators: name: Kim, Minjin
name: Ho, Luis C.
name: Im, Myungshin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The Seyfert 2 galaxy NGC 5252 contains a recently identified ultra-luminous X-ray (ULX) source that has been suggested to be a possible candidate off-nuclear low-mass active galactic nucleus. We present follow-up optical integral-field unit observations obtained using GMOS on the Gemini-North telescope. In addition to confirming that the ionized gas in the vicinity of the ULX is kinematically associated with NGC 5252, the new observations reveal ordered motions consistent with rotation around the ULX. The close coincidence of the excitation source of the line-emitting gas with the position of the ULX further suggests that ULX itself is directly responsible for the ionization of the gas. The spatially resolved measurements of [N II] $λ$ 6584/H$α$ surrounding the ULX indicate a low gas-phase metallicity, consistent with those of other known low-mass active galaxies but not that of its more massive host galaxy. These findings strengthen the proposition that the ULX is not a background source, but rather that it is the nucleus of a small, low-mass galaxy accreted by NGC 5252.
description: to appear in ApJL
Formation of cooperative amidoaminocalixresorcinarene – methotrexate nanosized aggregates in an aqueous solution and on the surface of gold nanoparticles
Creators: name: Ya.V. Shalaeva
name: Ju. E. Morozova
name: V. V. Syakaev
name: A. M. Ermakova
name: I. R. Nizameev
name: M. K. Kadirov
name: E. Kh. Kazakova
name: A. I. Konovalov
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry

description: Cooperative nanoscale associates of amido(dimethylamino) calixresorcinarenes with pentyl (C5) and undecyl (C11) substituents on lower rim with antitumor drug-methotrexate (MTX) in aqueous solution and on the surface of gold nanoparticles C5@Au and C11@Au were formed. The formation of nanoparticles was investigated by 1H NMR, NMR FT-PGSE, 2D NOESY, DLS, TEM, spectrophotometry, fluorimetry. It was found that during the interaction of C5 or C11 macrocycles with MTX in aqueous solution, the latter generates dissociation of macrocycles self-associates with formation of cooperative macrocycle–MTX associates of smaller size due to multiple non-covalent interactions, which leads to increase in fluorescence intensity of MTX. In contrast, binding of MTX by macrocyclic associates preorganized as bilayer on surface of gold nanoparticles through electrostatic interactions induces aggregation of C5@Au-MTX or C11@Au-MTX associates, which results in quenching of MTX fluorescence in solution. Such particles have possible potential in the field of binding and delivery of antitumor drugs.
Trends in characteristics and outcomes among US adults hospitalised with COVID-19 throughout 2020: An observational cohort study
Creators: name: Keenan, H.A
name: Brown, C.A
name: Bennett, C
name: Xia, Q.
name: Londhe, A.A
name: Sanders, L
name: Critchlow, C.W
name: Bao, Y
name: He, F
name: Gill, K
name: Braunlin, M
name: Bradbury, B.D.
name: Gondek, K.
name: Petersen, J
name: Zhu, J.
name: Page, J.H
name: Jiang, J
name: Charuworn, P
name: Brooks, C
name: Wei, Z.
name: Devercelli, G
name: Ma, J
name: Ayodele, O
name: Roehl, K.A
name: Zhou, L.
name: Cheng, A
name: Zhang, J
name: Sprafka, J.M
name: Jonsson-Funk, M
name: Wang, L
name: Chang, S.-C.
name: Ren, K
name: Carlson, K.B
name: Yu, P.
Publisher: name: BMJ Publishing Group
Year: 2022

description: Objectives To examine the temporal patterns of patient characteristics, treatments used and outcomes associated with COVID-19 in patients who were hospitalised for the disease between January and 15 November 2020. Design Observational cohort study. Setting COVID-19 subset of the Optum deidentified electronic health records, including more than 1.8 million patients from across the USA. Participants There were 51 510 hospitalised patients who met the COVID-19 definition, with 37 617 in the laboratory positive cohort and 13 893 in the clinical cohort. Primary and secondary outcome measures Incident acute clinical outcomes, including in-hospital all-cause mortality. Results Respectively, 48% and 49% of the laboratory positive and clinical cohorts were women. The 50- 65 age group was the median age group for both cohorts. The use of antivirals and dexamethasone increased over time, fivefold and twofold, respectively, while the use of hydroxychloroquine declined by 98%. Among adult patients in the laboratory positive cohort, absolute age/sex standardised incidence proportion for in-hospital death changed by -0.036 per month (95% CI -0.042 to -0.031) from March to June 2020, but remained fairly flat from June to November, 2020 (0.001 (95% CI -0.001 to 0.003), 17.5% (660 deaths /3986 persons) in March and 10.2% (580/5137) in October); in the clinical cohort, the corresponding changes were -0.024 (95% CI -0.032 to -0.015) and 0.011 (95% CI 0.007 0.014), respectively (14.8% (175/1252) in March, 15.3% (189/1203) in October). Declines in the cumulative incidence of most acute clinical outcomes were observed in the laboratory positive cohort, but not for the clinical cohort. Conclusion The incidence of adverse clinical outcomes remains high among COVID-19 patients with clinical diagnosis only. Patients with COVID-19 entering the hospital are at elevated risk of adverse outcomes.
Topologically Unquenched QCD: Prospects from an explorative study in 2-flavour QED(2)
Creators: name: Dürr, Stephan
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: The concept of simulating a variant of QCD with sea quarks which interact with the gluon configuration only via global gluonic quantities like $\int F\tilde F dx$ and $\int FF dx$ is tested for the case of the massive 2-flavour Schwinger model. It is found to amount to an importance sampling method which generates -at essentially the costs of a quenched run- an ensemble in between a full and a quenched one, thus providing a competitive alternative to the quenched approximation.
description: 15 pages, 10 figures, revision: mistake in scale of some figures corrected, few minor changes in text, physics unaltered -- to appear in Phys. Rev. D