cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: Table S1. of Retinal capillary rarefaction in patients with untreated mild-moderate hypertension
Creators: name: Bosch, Agnes
name: Harazny, Joanna
name: Kistner, Iris
name: Friedrich, Stefanie
name: Wojtkiewicz, Joanna
name: Schmieder, Roland
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Patient characteristics of hypertensive study population compared to total hypertensive population. Table including patients characteristics of hypertensive study population compared to total hypertensive population. Hypertensive patients showed no difference in age, BMI, gender, duration of disease, blood pressure, heart rate, serum creatinine and serum cholesterol to those of the group with valid evaluation. (DOCX 28 kb)
Voltage Sensing in Bacterial Protein Translocation
Creators: name: Knyazev, Denis G.
name: Kuttner, Roland
name: Bondar, Ana-Nicoleta
name: Zimmerman, Mirjam
name: Siligan, Christine
name: Pohl, Peter
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: translocon
subject: SecY
subject: Sec61
subject: gating
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: The bacterial channel SecYEG efficiently translocates both hydrophobic and hydrophilic proteins across the plasma membrane. Translocating polypeptide chains may dislodge the plug, a half helix that blocks the permeation of small molecules, from its position in the middle of the aqueous translocation channel. Instead of the plug, six isoleucines in the middle of the membrane supposedly seal the channel, by forming a gasket around the translocating polypeptide. However, this hypothesis does not explain how the tightness of the gasket may depend on membrane potential. Here, we demonstrate voltage-dependent closings of the purified and reconstituted channel in the presence of ligands, suggesting that voltage sensitivity may be conferred by motor protein SecA, ribosomes, signal peptides, and/or translocating peptides. Yet, the presence of a voltage sensor intrinsic to SecYEG was indicated by voltage driven closure of pores that were forced-open either by crosslinking the plug to SecE or by plug deletion. We tested the involvement of SecY’s half-helix 2b (TM2b) in voltage sensing, since clearly identifiable gating charges are missing. The mutation L80D accelerated voltage driven closings by reversing TM2b’s dipolar orientation. In contrast, the L80K mutation decelerated voltage induced closings by increasing TM2b’s dipole moment. The observations suggest that TM2b is part of a larger voltage sensor. By partly aligning the combined dipole of this sensor with the orientation of the membrane-spanning electric field, voltage may drive channel closure.
Quantum properties of a parametric four-wave mixing in a Raman-type atomic system
Creators: name: Sharypov, A. V.
name: He, Bing
name: Arkhipkin, V. G.
name: Myslivets, S. A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We present a study of the quantum properties of two light fields used to parametric four-wave mixing in a Raman-type atomic system. The system realizes an effective Hamiltonian of beamsplitter type coupling between the light fields, which allows to control squeezing and amplitude distribution of the light fields, as well as realizing their entanglement. The scheme can be feasibly applied to engineer the quantum properties of two single-mode light fields in properly chosen input states.
description: 6 pages, 4 figures
title: Asian American Heritage Seeking: Personal Narrative Performances of Ancestral Return
Creators: name: Twishime, Porntip Israsena
Publisher: name: University of Massachusetts Amherst
Year: 2018

description: Asian American belongings, migration patterns, and transnational identities are largely constructed in the United States as static, unidirectional, and invisible. Asian Americans complicate these constructions through the practice of ancestral return. In this thesis, “ancestral return” is constituted through one’s participation in a university study abroad program to a specific place to where one traces her heritage. I use “return” not necessarily to account for a form of reverse migration; rather “return” here names the multiple, sometimes contradictory kinds of return, including “return” to a place that one has not yet been. This project examines how Asian American identities are constructed, disrupted, and transformed when Asian Americans traverse borders, time, and imaginaries. I use a performance ethnography and personal narrative performance methodology to center the memories and experiences of Asian American women who have practiced ancestral return. Personal narrative performances theorize Asian American belongings, migration patterns, and transnational identities within the context of complex and contradictory practices of ancestral return. This work contributes to the theorization of personal narrative performance as well as a growing literature on the return mobilities of the Asian American second-generation and beyond.
An update on drug–drug interactions in older adults living with human immunodeficiency virus (HIV)
Creators: name: Linfield, Rebecca Y.
name: Nguyen, Nancy N.
name: Laprade, Olivia H.
name: Holodniy, Mark
name: Chary, Aarthi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: People with HIV are living longer due to advances in antiretroviral therapy. With improved life expectancy comes an increased lifetime risk of comorbid conditions – such as cardiovascular disease and cancer – and polypharmacy. Older adults, particularly those living with HIV, are more vulnerable to drug interactions and adverse effects, resulting in negative health outcomes. Antiretrovirals are involved in many potential drug interactions with medications used to treat common comorbidities and geriatric conditions in an aging population of people with HIV. We review the mechanisms and management of significant drug–drug interactions involving antiretroviral medications and non-antiretroviral medications commonly used among older people living with HIV. The management of these interactions may require dose adjustments, medication switches to alternatives, enhanced monitoring, and considerations of patient- and disease-specific factors. Clinicians managing comorbid conditions among older people with HIV must be particularly vigilant to side effect profiles, drug–drug interactions, pill burden, and cost when optimizing treatment. To support healthier aging among people living with HIV, there is a growing need for antiretroviral stewardship, multidisciplinary care models, and advances that promote insight into the correlations between an individual, their conditions, and their medications.
Fiction and the moral imagination,: & The swing of the sea : a novel
Creators: name: Throsby, Eleanor Robin
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This creative writing thesis examines the role of the moral imagination in the reading and writing of fiction through a theoretical investigation of its history and influence, both on literary criticism and on the practice of fiction writing. The creative part of the thesis consistsof a novel that reflects the ideas explored in the theoretical part of the thesis. Moral imagination is defined as being the human capacity to enter imaginatively into the situations of others who may be very different from ourselves. The central proposition of the thesis is that fiction is peculiarly positioned to exercise a reader's moral imagination through its capacity to show the complexity and difficulty of ethical choice. Relevant literary and philosophical positions are evaluated, and it is argued that the moral imagination offers a conceptual framework embracing both the emotional and intellectual aspects of ethical dilemmas. It is further argued that an appreciation of alterity lies at the heart of morality and that the postmodern era of literary criticism, often seen as antithetical to the practice of ethical criticism, has been misinterpreted. The novel The Swing of the Sea forms the creative part of the thesis. It is set in Sydney between the years 1996 and 2007. The novel's main protagonist, Stephen, is a progressive thinker, critical of government ethics, while making some dubious choices of his own. Stephen and his family live in a period of conflict and violence in the world around them, while feeling safe in their comfortable suburb. One night, complacency is shattered by a terrible unpredictable event, after which everything changes for Stephen as he is forced to comprehend the nature of personal responsibility. The novel explores the parallels between the political and the personal and the way human behaviour is affected by the overarching cultural context in which it occurs.
title: ADCO, Cartulaire du prieuré Notre-Dame de Bonvaux, dépendant du Val-des-Ecoliers (XVe siècle), Dijon, Cart. 228 (27 H), 68 folios, 109 actes (1211-1356), f. 0072
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire du prieuré Notre-Dame de Bonvaux, dépendant du Val-des-Ecoliers (XVe siècle), Dijon, Archives départementales de la Côte-d'Or, Cart. 228 (27 H), 68 folios, 109 actes (1211-1356). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire du prieuré Notre-Dame de Bonvaux, dépendant du Val-des-Ecoliers (XVe siècle), Dijon, Archives départementales de la Côte-d'Or, Cart. 228 (27 H), 68 folios, 109 actes (1211-1356), f. 0072, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb15250518p
description: Provenance: http://www.idref.fr/02643413X/id
description: Provenance: https://www.geonames.org/6453767
description: Provenance: Dijon
description: Provenance: http://www.wikidata.org/entity/Q7003
Additional file 1 of Olverembatinib (HQP1351), a well-tolerated and effective tyrosine kinase inhibitor for patients with T315I-mutated chronic myeloid leukemia: results of an open-label, multicenter phase 1/2 trial
Creators: name: Jiang, Qian
name: Li, Zongru
name: Qin, Yazhen
name: Li, Weiming
name: Xu, Na
name: Liu, Bingcheng
name: Zhang, Yanli
name: Meng, Li
name: Zhu, Huanling
name: Du, Xin
name: Chen, Suning
name: Liang, Yang
name: Hu, Yu
name: Liu, Xiaoli
name: Song, Yongping
name: Men, Lichuang
name: Chen, Zi
name: Niu, Qian
name: Wang, Hengbang
name: Lu, Ming
name: Yang, Dajun
name: Zhai, Yifan
name: Huang, Xiaojun
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology

description: Additional file 1. Appendix: Supplementary tables and figures.
An update on drug-drug interactions in older adults living with human immunodeficiency virus (HIV)
Creators: name: Linfield, Rebecca Y.
name: Nguyen, Nancy N.
name: Laprade, Olivia H.
name: Holodniy, Mark
name: Chary, Aarthi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: People with HIV are living longer due to advances in antiretroviral therapy. With improved life expectancy comes an increased lifetime risk of comorbid conditions – such as cardiovascular disease and cancer – and polypharmacy. Older adults, particularly those living with HIV, are more vulnerable to drug interactions and adverse effects, resulting in negative health outcomes. Antiretrovirals are involved in many potential drug interactions with medications used to treat common comorbidities and geriatric conditions in an aging population of people with HIV. We review the mechanisms and management of significant drug-drug interactions involving antiretroviral medications and non-antiretroviral medications commonly used among older people living with HIV. The management of these interactions may require dose adjustments, medication switches to alternatives, enhanced monitoring, and considerations of patient- and disease-specific factors. Clinicians managing comorbid conditions among older people with HIV must be particularly vigilant to side effect profiles, drug-drug interactions, pill burden, and cost when optimizing treatment. To support healthier aging among people living with HIV, there is a growing need for antiretroviral stewardship, multidisciplinary care models, and advances that promote insight into the correlations between an individual, their conditions, and their medications.
The fundamental plane of evolving red nuggets
Creators: name: Oldham, Lindsay
name: Auger, Matt
name: Fassnacht, Chris
name: Treu, Tommaso
name: Koopmans, L. V. E.
name: Lagattuta, David
name: McKean, John
name: Vegetti, Simona
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present an exploration of the mass structure of a sample of 12 strongly lensed massive, compact early-type galaxies at redshifts $z\sim0.6$ to provide further possible evidence for their inside-out growth. We obtain new ESI/Keck spectroscopy and infer the kinematics of both lens and source galaxies, and combine these with existing photometry to construct (a) the fundamental plane (FP) of the source galaxies and (b) physical models for their dark and luminous mass structure. We find their FP to be tilted towards the virial plane relative to the local FP, and attribute this to their unusual compactness, which causes their kinematics to be totally dominated by the stellar mass as opposed to their dark matter; that their FP is nevertheless still inconsistent with the virial plane implies that both the stellar and dark structure of early-type galaxies is non-homologous. We also find the intrinsic scatter of their FP to be comparable to the local value, indicating that variations in the stellar mass structure outweight variations in the dark halo in the central regions of early-type galaxies. Finally, we show that inference on the dark halo structure -- and, in turn, the underlying physics -- is sensitive to assumptions about the stellar initial mass function (IMF), but that physically-motivated assumptions about the IMF imply haloes with sub-NFW inner density slopes, and may present further evidence for the inside-out growth of compact early-type galaxies via minor mergers and accretion.
description: 10 pages, 3 figures, 3 tables; submitted to MNRAS
Nabuapaka: social change in a Roro community
Creators: name: Monsell-Davis, Michael Dunmore
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This thesis is a study of the recent history and ethnography of the Roro people - Austronesian - speakers who live in the vicinity of Yule Island about 100 miles north west of Port Moresby. It shows that, like their neighbours the Mekeo, Roro have an authority structure that differs considerably from the big man systems commonly ascribed to Melanesia in that it is based on hereditary chiefs and sorcerers. -- The document indicates some of the changes that have taken place as Roro leadership and laws have been subordinated to a wider polity, and as they have come to depend on money rather than solely on the resources they obtained locally or through trade with their neighbours . In particularit shows the lessening of ceremonial, of chiefly prestige, and of people' s dependence on chiefs for initiative and resources. -- Despite the changes, however, the Roro traditiona l belief system has remained largely intact, in particular belief in the power of sorcery has enabled chiefs to retain control despite their waning prestige and commoner assertions that they are not doing their jobs. -- Finally the thesis shows the impact of the opening of the road between Bereina and Port Moresby in 1973. It has brought new Life to the village in that people can now travel easily between town and country, and those working in Moresby can return home often with money and news. But the road has also opened new opportunities for entrepreneurial enterprises such as transport and tradestores. The final part of the thesis examines some of the problems faced by these ventures, particularly the fears and guilt arising out of the clash between a growing, largely unperceived individualism and dependence on money, as against traditional values that stress equal access to resources and that prestige and status are normally conveyed only by birth. These values are supported by strong persisting fears of sorcery.
Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase (GAPDH) elicits multiple cytokines from human cells and has a minor effect on bacterial persistence in the murine female reproductive tract
Creators: name: Sullivan, Matthew J.
name: Goh, Kelvin G. K.
name: Thapa, Ruby
name: Chattopadhyay, Debasish
name: Ipe, Deepak S.
name: Duell, Benjamin L.
name: Katupitiya, Lahiru
name: Gosling, Dean
name: Acharya, Dhruba
name: Ulett, Glen C.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Streptococcus agalactiae glyceraldehyde 3-phosphate dehydrogenase (GAPDH), encoded by gapC, is a glycolytic enzyme that is associated with virulence and immune-mediated protection. However, the role of GAPDH in cellular cytokine responses to S. agalactiae, bacterial phagocytosis and colonization of the female reproductive tract, a central host niche, is unknown. We expressed and studied purified recombinant GAPDH (rGAPDH) of S. agalactiae in cytokine elicitation assays with human monocyte-derived macrophage, epithelial cell, and polymorphonuclear leukocyte (PMN) co-culture infection models. We also generated a S. agalactiae mutant that over-expresses GAPDH (oeGAPDH) from gapC using a constitutively active promoter, and analysed the mutant in murine macrophage antibiotic protection assays and in virulence assays in vivo, using a colonization model that is based on experimental infection of the reproductive tract in female mice. Human cell co-cultures produced interleukin (IL)-1β, IL-6, macrophage inflammatory protein (MIP)-1, tumour necrosis factor (TNF)-α and IL-10 within 24 h of exposure to rGAPDH. PMNs were required for several of these cytokine responses. However, over-expression of GAPDH in S. agalactiae did not significantly affect measures of phagocytic uptake compared to an empty vector control. In contrast, oeGAPDH-S. agalactiae showed a small but statistically significant attenuation for persistence in the reproductive tract of female mice during the chronic phase of infection (10-28 days post-inoculation), relative to the vector control. We conclude that S. agalactiae GAPDH elicits production of multiple cytokines from human cells, and over-expression of GAPDH renders the bacterium more susceptible to host clearance in the female reproductive tract. One-sentence summary: This study shows Streptococcus agalactiae glyceraldehyde 3-phosphate dehydrogenase, an enzyme that functions in glycolysis, gluconeogenesis and virulence, modifies phagocytosis outcomes, including cytokine synthesis, and effects bacterial persistence in the female reproductive tract.
title: ADCO, Cartulaire de Cîteaux pour les possessions de Magny-lès-Aubigny et Montot (XVe siècle), Cart. 183 (11 H 821), 21 folios, f. 0027
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
name: Archives Départementales De La Côte-D'Or
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Cîteaux pour les possessions de Magny-lès-Aubigny et Montot (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 183 (11 H 821), 21 folios, f. 0027, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Magny-lès-Aubigny et Montot (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 183 (11 H 821), 21 folios, f. 0027, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Computer-assisted characterization of the Rh system epitopes: Searching for the missing antigens. (hydrophobicity profile folder)
Creators: name: Estrada Juárez, Higinio
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310299
subject: Bioinformatics and computational biology not elsewhere classified
classificationCode: 320102
subject: Haematology

description: Possible epitopes of the 3D structures of RhD, RhCE, RhCe, RhcE, Rhce and variant proteins.E=EbC=Cbe=elc=clIf you cannot view the files in the browser, download them and use Pymol (https://www.pymol.org/)For the potential display use the command in Pymol: spectrum b, magenta_white_green, minimum=0.4, maximum=2.5
Post-translational knockdown and post-secretional modification of EsxA determine contribution of EsxA membrane permeabilizing activity for mycobacterial intracellular survival
Creators: name: Bao, Yanqing
name: Wang, Lin
name: Sun, Jianjun
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Current genetic studies (e.g. gene knockout) have suggested that EsxA and EsxB function as secreted virulence factors that are essential for Mycobaterium tuberculosis (Mtb) intracellular survival, specifically in mediating phagosome rupture and translocation of Mtb to the cytosol of host cells, which further facilitates Mtb intracellular replicating and cell-to-cell spreading. The EsxA-mediated intracellular survival is presumably achieved by its pH-dependent membrane-permeabilizing activity (MPA). However, the data from other studies have generated a discrepancy regarding the role of EsxA MPA in mycobacterial intracellular survival, which has raised a concern that genetic manipulations, such as deletion of esxB-esxA operon or RD-1 locus, may affect other codependently secreted factors that could be also directly involved cytosolic translocation, or stimulate extended disturbance on other genes’ expression. To avoid the drawbacks of gene knockout, we first engineered a Mycobacterium marinum (Mm) strain, in which a DAS4+ tag was fused to the C-terminus of EsxB to allow inducible knockdown of EsxB (also EsxA) at the post-translational level. We also engineered an Mm strain by fusing a SpyTag (ST) to the C-terminus of EsxA, which allowed inhibition of EsxA-ST MPA at the post-secretional level through a covalent linkage to SpyCatcher-GFP. Both post-translational knockdown and functional inhibition of EsxA resulted in attenuation of Mm intracellular survival in lung epithelial cells or macrophages, which unambiguously confirms the direct role of EsxA MPA in mycobacterial intracellular survival.
ศักยภาพการปรับตัวของผู้ผลิตชิ้นส่วนยานยนต์ไทย ในการเปลี่ยนผ่านสู่ยุคเทคโนโลยียานยนต์ไฟฟ้า
Creators: name: อัญชนา ส่วนมนทิระ
name: พิชญ์สินี ตัณฑเสน
name: บุรพร กําบุญ
name: ศิริชญาน์ การะเวก
Publisher: name: สมาคมปรัชญาดุษฎีบัณฑิตทางสังคมศาสตร์ มหาวิทยาลัยรามคำแหง
Year: 2563
Subjects: เทคโนโลยียานยนต์ไฟฟ้า
ศักยภาพการปรับตัว
ผู้ผลิตชิ้นส่วนยานยนต์ไทย
Electric Vehicle Technology
Adaptability Potential
Thai Auto Parts Manufacture

description: วารสารดุษฎีบัณฑิตทางสังคมศาสตร์, 10, 2, 416-427
Use of decitabine for patients with refractory or relapsed acute myeloid leukemia: a systematic review and meta-analysis
Creators: name: Ma, Yuan-yuan
name: Zhao, Min
name: Liu, Yi
name: Zhao, De-feng
name: Wang, Li-xin
name: Chen, Xiao-ping
name: Li, Li
Publisher: name: Taylor & Francis
Year: 2019
Subjects: Medicine
Cancer
Science Policy
Hematology

description: Background: Approximately, one-third of adult patients with acute myeloid leukemia (AML) are refractory to initial induction chemotherapy and relapse occurs in most patients who achieve remission. This study evaluates the efficacy of decitabine in the management of refractory or relapsed AML. Methods: After literature search in electronic databases (Google Scholar, Embase, Ovid, and PubMed) studies were selected by following pre-determined eligibility criteria. Random-effects meta-analyses were performed to achieve effect sizes of complete remission (CR) rate, response rate (RR), and median survival after therapy. Subgroup analyses were performed with regards to use of decitabine with either epigenetics-based therapy, molecular therapy or chemotherapy. Results: Twenty studies were included (310 patients; age 55.1 years [95% confidence interval (CI): 43.8, 66.4]; 57% [52%, 63%] males). Overall RR was 46.1% [95% CI: 36.1%, 56.1%]. Overall CR rate was 23.5% [95% CI: 22.1%, 24.9%] but was 14.85% [95% CI: 3.8%, 25.9%] for decitabine with epigenetics-based therapies, 15.4% [95% CI: 6.7%, 24.0%] for decitabine with immunotherapy or molecular therapy, 34.8% [95% CI: 18.7%, 50.9%] for decitabine with chemotherapy, and 37.5% [36.4%, 38.7%] for decitabine with chemotherapy and molecular therapy. Median survival was 7.2 months [95% CI: 5.17, 9.3]. Major adverse events were neutropenia, nausea/vomiting, infections, fatigue, febrile neutropenia, diarrhea, thrombocytopenia, anemia, anorexia, leukopenia, hemorrhage, and hyperglycemia. Conclusion: Decitabine in combination with chemotherapy or molecular therapy has shown efficacious properties in refractory or relapsed AML patients.
Physical Properties of Sub-galactic Clumps at 0.5 $\leq z \leq$ 1.5 in the UVUDF
Creators: name: Soto, Emmaris
name: de Mello, Duilia F.
name: Rafelski, Marc
name: Gardner, Jonathan P.
name: Teplitz, Harry I.
name: Koekemoer, Anton M.
name: Ravindranath, Swara
name: Grogin, Norman A.
name: Scarlata, Claudia
name: Kurczynski, Peter
name: Gawiser, Eric
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present an investigation of clumpy galaxies in the Hubble Ultra Deep Field at 0.5 $\leq z \leq$ 1.5 in the rest-frame far-ultraviolet (FUV) using HST WFC3 broadband imaging in F225W, F275W, and F336W. An analysis of 1,404 galaxies yields 209 galaxies that host 403 kpc-scale clumps. These host galaxies appear to be typical star-forming galaxies, with an average of 2 clumps per galaxy and reaching a maximum of 8 clumps. We measure the photometry of the clumps, and determine the mass, age, and star formation rates (SFR) utilizing the SED-fitting code FAST. We find that clumps make an average contribution of 19% to the total rest-frame FUV flux of their host galaxy. Individually, clumps contribute a median of 5% to the host galaxy SFR and an average of $\sim$4% to the host galaxy mass, with total clump contributions to the host galaxy stellar mass ranging widely from less than 1% up to 93%. Clumps in the outskirts of galaxies are typically younger, with higher star formation rates, than clumps in the inner regions. The results are consistent with clump migration theories in which clumps form through violent gravitational instabilities in gas-rich turbulent disks, eventually migrate toward the center of the galaxies, and coalesce into the bulge.
description: Accepted for publication in ApJ. 18 pages, 18 figures
Complicit institutions: representation, consumption and the production of school violence
Creators: name: Saltmarsh, Sue
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This study integrates sociological theories of social class with poststructuralist theories of subjectivity, representation and consumption, to consider the complex ways in which the representational practices of institutions and individuals are implicated in the production of violence in schools. This work draws particularly on a case study of incidents of sexual violence which occurred at an elite private school in Sydney during 2000, in which four students were charged with a range of offences committed against younger peers over a period of months. The assault incidents received widespread media coverage and sparked intense public debate, in response to which a media strategies consultant was engaged by the school to liaise with members of the press. This study demonstrates the extent to which the interrelationships between systems of signification (in particular, written and visual texts) and other social systems, (for example, families, schools, and political economy) function in the constitution of subjectivities and the production of meaning, and takes as its focus the interrelationship and functioning of texts, discursive practices and social practices which pertain specifically to the assault incidents described above. Data are derived from a range of sources and genres, including promotional materials, personal and general correspondence, media reports, and interviews, necessitating a variety of qualitative analytic methods. Informed by critical post-structuralist theory, in particular the work of Bourdieu, Foucault, and de Certeau, this work considers questions pertaining to the operation of power within social institutions, with particular emphasis on the constitutive function of discourse. The analysis extends current conceptualisations of school violence through a post-structuralist interrogation of, and linking of violence to, educational consumption, which has predominantly been theorised according to sociological or economic models. The argument is made that the market ideologies which pervade contemporary social and educative practice, together with the representational practices and disciplinary regimes of schools, function in the constitution of social subjects who occupy multiple ambiguous subject positions in the patriarchal hierarchies which characterise the power relations and institutions under consideration, thus implicating institutions in the production of violence.
Additional file 2: of Additive effect of tDCS combined with Peripheral Electrical Stimulation to an exercise program in pain control in knee osteoarthritis: study protocol for a randomized controlled trial
Creators: name: Cleber Luz-Santos
name: Camatti, Janine Ribeiro
name: Alaí Barbosa Paixão
name: Sá, Katia Nunes
name: Montoya, Pedro
name: Lee, Michael
name: Abrahão Fontes Baptista
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Science Policy

description: SPIRIT 2013 Checklist: recommended items to address in a clinical trial protocol and related documents*. (DOCX 49 kb)
หลักการทางกฎหมายในการแสวงหาพยานหลักฐานคดียาเสพติดด้วยวิธีการอําพรางตัว
Creators: name: กุลทิตา ยุวะหงษ์
name: จรัล เล็งวิทยา
Publisher: name: สมาคมปรัชญาดุษฎีบัณฑิตทางสังคมศาสตร์ มหาวิทยาลัยรามคำแหง
Year: 2563
Subjects: การแสวงหาพยานหลักฐาน
การอำพรางตัว
คดียาเสพติด
Legal Principles
Seeking Evidences
Undercover

description: วารสารดุษฎีบัณฑิตทางสังคมศาสตร์, 10, 2, 428-438
Helicobacter pylori cholesterol-α-glucosyltransferase manipulates cholesterol for bacterial adherence to gastric epithelial cells
Creators: name: Hsu, Chung-Yao
name: Yeh, Jia-Yin
name: Chen, Chun-Ya
name: Wu, Hui-Yu
name: Chiang, Meng-Hsuan
name: Wu, Chia-Lin
name: Lin, Hwai-Jeng
name: Chiu, Cheng-Hsun
name: Lai, Chih-Ho
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Helicobacter pylori infection is associated with several gastrointestinal diseases, including gastritis, peptic ulcers, and gastric cancer. Infection of cells with H. pylori is dependent on lipid rafts, which are cholesterol-rich microdomains located in the cell membrane. H. pylori cholesterol-α-glucosyltransferase (CGT) catalyzes the conversion of membrane cholesterol to cholesteryl glucosides, which can be incorporated into the bacterial cell wall, facilitating evasion from immune defense and colonization in the host. However, the detailed mechanisms underlying this process remain to be explored. In this study, we discovered for the first time that H. pylori CGT could promote adherence to gastric epithelial cells in a cholesterol-dependent manner. Externalization of cell membrane phosphatidylserine (PS) is crucial for enhancement of binding of H. pylori to cells by CGT and for cytotoxin-associated gene A (CagA)-induced pathogenesis. Furthermore, exogenous cholesterol interferes with the actions of H. pylori CGT to catalyze cellular cholesterol, which impedes bacterial binding to cells and attenuates subsequent inflammation, indicating that the initial attachment of H. pylori to cells is closely dependent on host cholesterol. These results provide evidence that CGT contributes to H. pylori infectivity and it may serve as a key target for the treatment of H. pylori-associated diseases.
An Ising Model for Metal-Organic Frameworks
Creators: name: Höft, Nicolas
name: Horbach, Jürgen
name: Martin-Mayor, Victor
name: Seoane, Beatriz
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We present a three-dimensional Ising model where lines of equal spins are frozen in such that they form an ordered framework structure. The frame spins impose an external field on the rest of the spins (active spins). We demonstrate that this "porous Ising model" can be seen as a minimal model for condensation transitions of gas molecules in metal-organic frameworks. Using Monte Carlo simulation techniques, we compare the phase behavior of a porous Ising model with that of a particle-based model for the condensation of methane (CH$_4$) in the isoreticular metal-organic framework IRMOF-16. For both models, we find a line of first-order phase transitions that end in a critical point. We show that the critical behavior in both cases belongs to the 3D Ising universality class, in contrast to other phase transitions in confinement such as capillary condensation.
description: 11 pages, 9 figures
Elevated CO2 weakens the shift in bacterial community structure in response to 8-year soybean straw return in the same experiment
Creators: name: Miao, Shujie
name: Zhao, Hongfei
name: Pan, Shiqiu
name: Zhang, Nan
name: Qiao, Yunfa
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: A potentially important source for soil organic carbon (SOC) in the agricultural ecosystem is straw, straw return has been shown to affect soil bacterial communities. Facing global climate change, the response of bacterial communities to straw return will change at CO2 enrichment. In this study, we investigate the changes of bacterial communities in response to straw return (+straw) at elevated CO2 (eCO2, 700 ppm) in a long-term field experiment of northeast China. Soil samples were taken in the eighth year and analyzed by high throughput sequencing. Soil bacterial communities exhibited distinct clustering according to straw return and eCO2, while eCO2 shortened the distance of clustering between straw return and not. The relative abundances of 10 genera (Acidobacteria_norank, Candidatus_Solibacter, Gaiella, Nocardioides, Streptomyces, C0119_norank, Roseiflexus, Gemmatimonas, Mizugakiibacter and Rhodanobacter) were significantly affected by the interaction of straw × eCO2. In addition, straw return significantly decreased the relative abundances of Gaiellales_norank, Blastococcus, Psedarthrobacter, and Bacillus and increased that of Geminatimonadaceae_norank, Tepidisphaeraceae, Nitrosomonadaceae_norank, and SC-I-84_norank. These differential responses of genera abundances are illustrative of the susceptibility of bacterial communities and indicate their importance in evaluating the fate of exogenous C. The Clusters of Orthologous Groups (COG) analysis showed that straw return had a greater effect on the relative abundances of COG categories than eCO2. The present results point to the need to focus more strongly on the turnover and storage of straw-C during a chronic straw return in the future.
หลักประกันความเป็นอิสระและหลักประกันการปฏิบัติหน้าที่ของสํานักงานอัยการสูงสุด
Creators: name: จิตติมา ราชรักษ
name: สุขสมัย สุทธิบดี
name: อุทัย อาทิเวช
name: ศุภกิตต์ จรูญโรจน์
Publisher: name: สมาคมปรัชญาดุษฎีบัณฑิตทางสังคมศาสตร์ มหาวิทยาลัยรามคำแหง
Year: 2563
Subjects: หลักประกันความเป็นอิสระ
หลักประกันการปฏิบัติหน้าที่
สำนักงานอัยการสูงสุด
Independence Security
Performance Security
Office of the Attorney General

description: วารสารดุษฎีบัณฑิตทางสังคมศาสตร์, 10, 2, 439-450
Mathematical modelling of the electric sense of fish: the role of multi-frequency measurements and movement
Creators: name: Ammari, Habib
name: Boulier, Thomas
name: Garnier, Josselin
name: Wang, Han
Publisher: name: arXiv
Year: 2016
Subjects: subject: Tissues and Organs (q-bio.TO)
subject: FOS: Biological sciences

description: Understanding active electrolocation in weakly electric fish remains a challenging issue. In this article we propose a mathematical formulation of this problem, in terms of partial differential equations. This allows us to detail two algorithms: one for localizing a target using the multi-frequency aspect of the signal, and antoher one for identifying the shape of this target. Shape recognition is designed in a machine learning point of view, and take advantage of both the multi-frequency setup and the movement of the fish around its prey. Numerical simulations are shown for the computation of the electric field emitted and sensed by the fish; they are then used as an input for the two algorithms.
description: 16 pages, 7 figures
Structural evolution and stability of plutonium oxide clusters
Creators: name: Fu, Peixin
name: Jin, Siyu
name: Zhang, Lili
name: Jin, Yuanyuan
name: Chen, Bole
name: Qiu, Ruizhi
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Developmental Biology
subject: Computational Biology

description: Plutonium oxide clusters have attracted great interest as potential complex for the separation or storage of radioactive plutonium elements. However, the structural stability, chemical bonding mechanism and maximum oxygen adsorption capacity for plutonium oxygen clusters are not well understood due to the difference between the radial distribution function and orbital energy of the plutonium atom. Here, we systematically study the structural evolution and electronic properties of plutonium oxygen clusters with cluster sizes n from 2 to 15 by using the CALYPSO cluster structural prediction method in combination with density functional theory (DFT) calculations. The low-lying isomers searched by the CALYPSO method are re-optimised at the theoretical level of B3LYP/ECP60MWB(Pu)/aug-cc-pVTZ(O). Relative stability results indicate that the PuO8 cluster with CS symmetry is the most stable cluster due to the large HOMO–LUMO gap (of 4.84 eV). The high stability of PuO8 cluster is predominantly attributed to the strong interactions between Pu-5f orbitals and O-2p orbitals. The Pu atom can chemically adsorb up to eight O atoms, and the corresponding adsorption energy is −3.84 eV. The present findings shed light on the complex chemical bonding and structural evolution mechanisms of plutonium oxide clusters, which may facilitate the rational design and the synthesis of other actinide-oxygen clusters. Plutonium chemically adsorbs eight oxygen atoms, and its high stability is attributed to the interactions between Pu-5f and O-2p orbitals.
Cas A and the Crab Were Not Stellar Binaries At Death
Creators: name: Kochanek, C. S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The majority of massive stars are in binaries, which implies that many core collapse supernovae (ccSNe) should be binaries at the time of the explosion. Here we show that the three most recent, local (visual) SNe (the Crab, CasA and SN1987A) were not binaries, with limits on the initial mass ratios of q=M2/M1<0.1. No quantitative limits have previously been set for CasA and the Crab, while for SN1987A we merely updated existing limits in view of new estimates of the dust content. The lack of stellar companions to these three ccSNe implies a 90% confidence upper limit on the q>0.1 binary fraction at death of fb<44%. In a passively evolving binary model (meaning no binary interactions), with a flat mass ratio distribution and a Salpeter IMF, the resulting 90% confidence upper limit on the initial binary fraction of F<63% is in considerable tension with observed massive binary statistics. Allowing a significant fraction fM~25% of stellar binaries to merge reduces the tension, with F<63/(1-fM)~81%, but allowing for the significant fraction in higher order systems (triples, etc.) reintroduces the tension. That CasA was not a stellar binary at death also shows that a massive binary companion is not necessary for producing a Type IIb SNe. Much larger surveys for binary companions to Galactic SNe will become feasible with the release of the full Gaia proper motion and parallax catalogs, providing a powerful probe of the statistics of such binaries and their role in massive star evolution, neutron star velocity distributions and runaway stars.
description: 12 pages, 6 figures, submitted to MNRAS
The Stummer’s Racerunner (Eremias stummeri Wettstein, 1940) does occur in Northwest China
Creators: name: Liu, Jinlong
name: Dujsebayeva, Tatjana N.
name: Chirikova, Marina A.
name: Song, Qi
name: Gong, Xiong
name: Guo, Xianguang
Publisher: name: Brill Online
Year: 2020
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified

description: The status of Eremias
stummeri in China has been a matter of controversy for over two decades,
although it is well acknowledged that this species occurs in Northeast
Kyrgyzstan and Southeast Kazakhstan. To date, whether its occurrence extends to
the adjacent Chinese region (possibly in the Ily River Valley) has not been
confirmed yet. To overcome constraints on field surveys imposed by the
region’s remoteness and rugged terrain, we targeted areas of further field
inventories by estimating the potential distribution of the species. Ecological niche modeling (ENM) enabled us to
predict a continuous distribution area from Kazakhstan to the Chinese part of
the Ily River Valley in Zhaosu county for the species’ occurrence. We conducted
extensive field surveys in the predicted area. In 2017, for the first time, the
occurrence of E. stummeri in China was confirmed with a single find in
Zhaosu county. Further morphological and multilocus phylogenetic analyses
congruently supported the taxonomic status of the recently discovered
population as E. stummeri. In
contrast to its distribution continuity between Kazakhstan and China, the ENM
indicates distribution discontinuity between Kazakhstan and Kyrgyzstan. This geographic distribution pattern of E. stummeri is supported by morphological and molecular evidence,
which highlights that individuals from China and Kazakhstan are more closely
related to each other than to those from Kyrgyzstan. The mismatch between
mitochondrial and nuclear phylogeographic pattern implies that historical
mitochondrial introgression occurred from E.
stummeri individuals from Kyrgyzstan to those from
Kazakhstan.
title: ADCO, Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402) (11 H 1160), f. 00501
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: Petot, Frédéric
name: CBMA/CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160), f. 00501, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v