The prognostic importance of right ventricular longitudinal strain in patients with cardiomyopathies, connective tissue diseases, coronary artery disease, and congenital heart diseases
Creators: name: Tadic, Marijana
name: Kersten, Johannes
name: Nita, Nicoleta
name: Schneider, Leonhard
name: Buckert, Dominik
name: Gonska, Birgid
name: Scharnbeck, Dominik
name: Dahme, Tilmann
name: Imhof, Armin
name: Belyavskiy, Evgeny
name: Cuspidi, Cesare
name: Rottbauer, Wolfgang
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: right ventricle
subject: strain
subject: cardiomyopathy
subject: systemic sclerosis
subject: lupus
subject: DDC 610 / Medicine &amp; health
subject: Cardiomyopathies
subject: Myocardial infarction
subject: Amyloidosis
subject: Echocardiography
subject: Magnetic resonance imaging
subject: Scleroderma, Systemic
subject: Herzmuskelkrankheit
subject: Herzinfarkt
subject: Amyloidose
subject: Kernspintomografie
subject: Progressive Sklerodermie

description: first_pagesettings Open AccessReview The Prognostic Importance of Right Ventricular Longitudinal Strain in Patients with Cardiomyopathies, Connective Tissue Diseases, Coronary Artery Disease, and Congenital Heart Diseases by Marijana Tadic 1,*ORCID,Johannes Kersten 1ORCID,Nicoleta Nita 1,Leonhard Schneider 1,Dominik Buckert 1,Birgid Gonska 1,Dominik Scharnbeck 1,Tilman Dahme 1,Armin Imhof 1,Evgeny Belyavskiy 2,Cesare Cuspidi 3 andWolfgang Rottbauer 1 1 Klinik für Innere Medizin II, Universitätsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany 2 Department of Cardiology, Charité—Universitätsmedizin Berlin (Campus Virchow-Klinikum), 13353 Berlin, Germany 3 Department of Medicine and Surgery, University of Milan-Bicocca, 20126 Milan, Italy * Author to whom correspondence should be addressed. Academic Editor: Michael Henein Diagnostics 2021, 11(6), 954; https://doi.org/10.3390/diagnostics11060954 Received: 4 May 2021 / Revised: 18 May 2021 / Accepted: 21 May 2021 / Published: 26 May 2021 (This article belongs to the Special Issue Clinical Relevance and Usefulness of Strain Imaging) Download PDF Browse Figures Citation Export Abstract Right ventricular (RV) systolic function represents an important independent predictor of adverse outcomes in many cardiovascular (CV) diseases. However, conventional parameters of RV systolic function (tricuspid annular plane excursion (TAPSE), RV myocardial performance index (MPI), and fractional area change (FAC)) are not always able to detect subtle changes in RV function. New evidence indicates a significantly higher predictive value of RV longitudinal strain (LS) over conventional parameters. RVLS showed higher sensitivity and specificity in the detection of RV dysfunction in the absence of RV dilatation, apparent wall motion abnormalities, and reduced global RV systolic function. Additionally, RVLS represents a significant and independent predictor of adverse outcomes in patients with dilated cardiomyopathy (CMP), hypertrophic CMP, arrhythmogenic RV CMP, and amyloidosis, but also in patients with connective tissue diseases and patients with coronary artery disease. Due to its availability, echocardiography remains the main imaging tool for RVLS assessment, but cardiac magnetic resonance (CMR) also represents an important additional imaging tool in RVLG assessment. The findings from the large studies support the routine evaluation of RVLS in the majority of CV patients, but this has still not been adopted in daily clinical practice. This clinical review aims to summarize the significance and predictive value of RVLS in patients with different types of cardiomyopathies, tissue connective diseases, and coronary artery disease.