title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸ Ð¿Ð¾Ð·Ð¸ÑÐ¸Ð¾Ð½ÐµÑÐ° Ð´Ð»Ñ Ð°Ð¿Ð¿Ð°ÑÐ°ÑÐ½Ð¾-Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð¾Ð³Ð¾ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ° Ð¾Ð´Ð½Ð¾Ð¼Ð¾Ð»ÐµÐºÑÐ»ÑÑÐ½Ð¾Ð³Ð¾ ÑÐµÐºÐ²ÐµÐ½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Development of a positioner design for a single-molecular sequencing hardware and software complex
Creators: name: ÐÐ¸Ð½Ð¸Ð³ÑÐ±Ð°ÐµÐ²Ð°, ÐÐ¹ÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2023
Subjects: ÑÐµÐºÐ²ÐµÐ½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ°
Ð¾Ð´Ð½Ð¾Ð¼Ð¾Ð»ÐµÐºÑÐ»ÑÑÐ½Ð¾Ðµ ÑÐµÐºÐ²ÐµÐ½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
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ÐºÐ¾Ð½ÑÑÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
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Ð¿Ð¾Ð·Ð¸ÑÐ¸Ð¾Ð½ÐµÑ
Ð¿ÑÐ¾Ð±Ð¾Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ°
sequencing
development
singemolecular sequencing
sequencer
desing
hardware and software complex
positioner
sample preparation

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description: The given work is devoted to the development of a prototype positioner for a hardware-software complex of single-molecular sequencing. During the implementation of the masters thesis, materials developed and obtained during the preparation of an explanatory note (PP) for the stages of the Preliminary and Technical Research program of the IAP RAS on the topic "Development of a prototype of a single-molecular DNA sequencer, a set of reagents and consumables" were used. The purpose of our work was to develop a positioner. The positioner belongs to the sample preparation unit and performs the following functions: loading reagents/samples; moving the cell; moving disposable tips. To achieve this goal , we faced the following tasks: 1. To analyze analogs of devices for single-molecular sequencing. 2. Develop technical specifications for the positioner. 3. Describe the layout of the sample preparation unit and the structural division scheme. 4. Describe the choice of materials for the components of the positioner. 5. Describe the choice of gear belts. 6. Test the gear belts. 7. Conduct an experimental check of the positioners operability and positioning accuracy. As a result of the completion of the final qualifying work, all tasks were completed. After a series of tests, it was proved that the toothed belts are suitable for precise positioning. Scope of application: medicine, sanitary and epidemiological control, agriculture, criminology, biotechnology, fundamental research in the field of nucleic acid analysis.