cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Hydrodynamic lubrication of deep drawing
Creators: name: SHAO, Zhi-Min
Publisher: name: RMIT University
Year: 2024

description: An isoviscous steady hydrodynamic lubrication model for a deep drawing process is developed. Equations to calculate lubricant film thickness, radial, and drawing stresses are presented. The die inlet film thickness is related to the properties of the lubricant and the sheet metal, the tooling geometry and the operating conditions.

A series of experiments with low carbon steel sheet blanks and different types of lubricant was conducted. The formation of a thick hydrodynamic lubricant film associated with a matt surface finish was observed for using certain lubricants. In each experiment, the thickness of the lubricant film was estimated from the difference in diameter between the lubricated and unlubricated drawn cups.

The experimental measurements of lubricant film thickness and drawing force were compared with values calculated from the theoretical model. There is some degree of agreement between these results.
sj-docx-1-pie-10.1177_09544089231223035 - Supplemental material for Optimization of fused deposition modeling parameters to fabricate morphogenesis light weight structure with high tensile and compression strength
Creators: name: Baskar, R
name: Muthukumaran, V
name: Nandhakumar, S
name: Arivazhagan, S
Publisher: name: SAGE Journals
Year: 2024
Subjects: Engineering not elsewhere classified
Materials Engineering not elsewhere classified

description: Supplemental material, sj-docx-1-pie-10.1177_09544089231223035 for Optimization of fused deposition
modeling parameters to fabricate morphogenesis light weight structure
with high tensile and compression strength by R Baskar, V Muthukumaran, S Nandhakumar and S Arivazhagan in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering
Additional file 5 of Extracellular vesicle biomarkers in circulation for colorectal cancer detection: a systematic review and meta-analysis
Creators: name: Shi, Xianquan
name: Zhao, Xinyu
name: Xue, Jinru
name: Jia, Erna
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Supplementary Material 5
Additional file 6 of Extracellular vesicle biomarkers in circulation for colorectal cancer detection: a systematic review and meta-analysis
Creators: name: Shi, Xianquan
name: Zhao, Xinyu
name: Xue, Jinru
name: Jia, Erna
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Supplementary Material 6
Developing a project management office model for information technology projects in the financial sector in Singapore
Creators: name: TAN, Lee
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 339999
subject: Other built environment and design not elsewhere classified

description: Projects are unique endeavours that, in different ways, have to be managed from their inception to their completion. Contemporary project management embraces several approaches to this task. One such approach involves the establishment of a Project Management Office (PMO) within a host organisation. Establishing a PMO requires careful consideration and, while customisation of a PMO is inevitable, there exists a need for a model or template framework to guide this process.

This research develops a conceptual PMO model to guide organisations in building a PMO for Information Technology (IT) projects in Singapore’s financial industry. Effective PMOs in this sector should improve the chances of achieving project success through establishing and pursuing the significant relationships between critical characteristics of the PMO itself, the host organisation, the project managers, and the organisation’s project management maturity. Important considerations include the structure of a PMO and the roles it undertakes or is expected to undertake. Furthermore, with the introduction of Generation Y into the workforce, PMOs will need to take into consideration the unique perspective and values of this new cohort in the inter-generational aspects of the PMO in order to be relevant.

The research is to some extent theory building, since the untested final proposition is that, with an optimised form of structure and role definitions, PMOs can be better placed to improve the success rate of IT projects in the Singapore financial sector.

The outcome of this research is a theoretically based and practically relevant model that has been refined and validated. The research findings should advance project management knowledge and practice by providing guidance to organisations that plan to form a new PMO or restructure an existing functional unit. The opportunities for further related research could include applying the model to different types of projects, in different industries and in different countries.
title: Ποπ Καλαμάτα (Ελαιόλαδο, Επιτραπέζια Ελιά) – Ιστορική Ανασκόπηση
title: Pop Kalamata (Olive Oil, Table Olive) - Historical Review
titleType: AlternativeTitle
Creators: name: Ζυγουράκη, Ελένη
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2021
Subjects: subject: Ελαιοκομία
subject: Ελαιόλαδο -- Ελλάδα – Μεσσηνία(Νομός) -- Καλαμάτα -- Έρευνα
subject: Ελιά (Καρπός) -- Ελλάδα -- Μεσσηνία (Νομός) – Καλαμάτα – Έρευνα
subject: Eλαιόλαδο
subject: Eπιτραπέζιες ελιές
subject: Ποπ Καλαμών
subject: Ελιές Καλαμάτας
subject: Βιολογικές ιδιότητες
subject: AGROCERT
subject: Olive oil
subject: Table olives
subject: PDO Kalamon
subject: Kalamata olives
subject: Biological properties

description: Στην εργασία αυτή σκοπός είναι η παρουσίαση των προϊόντων ελαιόκαρπου ΠΟΠ Καλαμών καθώς και η εξέλιξη τους μέσα από την ιστορική αναδρομή στο Νομό Μεσσηνίας. Χωρισμένη η εργασία σε τέσσερα κύρια κεφάλαια. Το πρώτο κεφάλαιο αναφέρεται στην ιστορία της ελιάς και του ελαιόλαδου µε αναφορές από την αρχαιότητα έως σήμερα. Ενώ παράλληλα παρουσιάζονται και οι µαγικές ιδιότητες του ελαιολάδου. Το δεύτερο κεφάλαιο, παρουσιάζει τις ποικιλίες της ελιάς, οι οποίες υπολογίζονται παγκοσμίως ότι υπάρχουν σχεδόν 600 διαφορετικές ποικιλίες ελιάς, στην παρούσα εργασία αναφέρονται οι σημαντικότερες από αυτές. Συγκεκριμένα, στις ποικιλίες που έχουν διαχωριστεί σε ελαιοποιήσιµες, επιτραπέζιες και ποικιλίες διπλής χρήσης. Το τρίτο κεφάλαιο, επικεντρώνεται στα ΠΟΠ του λαδιού και της ελιάς. Αρχικά γίνεται επεξήγηση του όρου «προϊόν ΠΟΠ» και παρουσιάζονται τα κύρια χαρακτηριστικά της ελιάς και του ελαιόλαδου ΠΟΠ Καλαμάτας, ενώ επιπλέον μπαίνουν σε μια σειρά τα αντίστοιχα καταχωρημένα ΠΟΠ λαδιού και ελιάς. Στο τέταρτο και τελευταίο κεφάλαιο της εργασίας γίνεται αναφορά στην εξέλιξη του ΠΟΠ λαδιού και ελιάς Καλαμών στο νομό Μεσσηνίας άλλα και την επέκταση του σ’ άλλος νομούς, παρουσιάζοντας τα οφέλη και τις τάσεις και προοπτικές που επικράτησαν.
Additional file 7 of Extracellular vesicle biomarkers in circulation for colorectal cancer detection: a systematic review and meta-analysis
Creators: name: Shi, Xianquan
name: Zhao, Xinyu
name: Xue, Jinru
name: Jia, Erna
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Supplementary Material 7
Arbeitskarte Geographische Namen 1:100 000 Hoelfjella, Wohlthatmassiv, Antarktis
Creators: name: Bennat, Heinz
Publisher: name: Institut für Angewandte Geodäsie (Now: Bundesamt für Kartographie und Geodäsie), Frankfurt am Main
Year: 1998
Subjects: Antarctica
Geographical names
Wohlthatmassiv
Hoelfjella
Weyprechtberge
Payergruppe
Linnormen
lednik Mendeleeva
lednik Mušketova

description: Worksheet of Norwegian, Russian and German geograpical names, GeoMaud-Expedition 1995/96; All German place-names are listed that were clearly relatable and initially assigned to geographical objects during their discovery in 1938/39; The topography is coarsely portrayed by delimiting rocks and moraines and by 200 m contours;Scale: 1:100000;Projection: Polar Stereographic; Bounding Box: POLYGON  ((13 -71.6667, 15 -71.6667, 15 -72.3333, 13 -72.3333, 13 -71.6667)); Datum: GRS80
sj-docx-1-spo-10.1177_17479541241228059 - Supplemental material for Decoding the decade: Analyzing the evolution of technical and tactical performance in elite padel tennis (2011–2021)
Creators: name: Ungureanu, Alexandru Nicolae
name: Lupo, Corrado
name: Contardo, Matteo
name: Brustio, Paolo Riccardo
Publisher: name: SAGE Journals
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-1-spo-10.1177_17479541241228059 for Decoding the decade: Analyzing the evolution of technical and tactical performance in elite padel tennis
(2011–2021) by Alexandru Nicolae Ungureanu, Corrado Lupo, Matteo Contardo and Paolo Riccardo Brustio in International Journal of Sports Science & Coaching
Additional file 9 of Extracellular vesicle biomarkers in circulation for colorectal cancer detection: a systematic review and meta-analysis
Creators: name: Shi, Xianquan
name: Zhao, Xinyu
name: Xue, Jinru
name: Jia, Erna
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Supplementary Material 9
Additional file 10 of Extracellular vesicle biomarkers in circulation for colorectal cancer detection: a systematic review and meta-analysis
Creators: name: Shi, Xianquan
name: Zhao, Xinyu
name: Xue, Jinru
name: Jia, Erna
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Supplementary Material 10
title: Rezension: "Qualitativ-narrative Szenarios für die langfristige Entwicklung des polnischen Energiesektors. Eine energiegeographische Untersuchung" / Johannes Venjakob. Stuttgart: Ibidem, 2012. ISBN 978-3-8382-0354-6
Creators: name: Flade, Falk
name: Digitale Wissenschaftsplattform Pol-Int (Www.Pol-Int.Org)
Publisher: name: Europa-Universität Viadrina Frankfurt
Year: 2022

description: Johannes Venjakob analysiert in seiner Doktorarbeit die Entwicklung des polnischen Energiesektors mit einem Zeithorizont bis 2050. Besondere Berücksichtigung finden dabei erneuerbare Energien. Der Autor nutzt Ansätze aus Geographie, Zukunftsforschung und den Wirtschaftswissenschaften. Mit seinem interdisziplinären Vorgehen möchte der Autor darüber hinaus einen Beitrag zur methodischen Weiterentwicklung der geographischen Energieforschung leisten. Venjakob kommt unter anderem zu dem Ergebnis, dass der Ausbau erneuerbarer Energien in Polen durch ein inflexibles Energiesystem gehemmt wird. Diese Hemmnisse stellen möglicherweise sogar das Erreichen der europäischen Klimaschutzziele bis 2020 in Frage. Die Ursachen sind nach Meinung des Autors eher auf technologischer, denn auf institutioneller oder akteursbezogener Ebene zu suchen.
Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis
Creators: name: Bogdanow, Boris
name: Schmidt, Max
name: Weisbach, Henry
name: Gruska, Iris
name: Vetter, Barbara
name: Imami, Koshi
name: Ostermann, Eleonore
name: Brune, Wolfram
name: Selbach, Matthias
name: Hagemeier, Christian
name: Wiebusch, Lüder
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Animals
subject: Cyclin A
subject: Cytomegalovirus
subject: DNA
subject: DNA Replication
subject: HEK293 Cells
subject: Herpesviridae
subject: Herpesviridae Infections
subject: NIH 3T3 Cells
subject: Nuclear Localization Signals
subject: Phosphorylation
subject: Protein Interaction Maps
subject: Protein Kinases
subject: Viral Proteins
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Herpesviruses encode conserved protein kinases (CHPKs) to stimulate phosphorylation-sensitive processes during infection. How CHPKs bind to cellular factors and how this impacts their regulatory functions is poorly understood. Here, we use quantitative proteomics to determine cellular interaction partners of human herpesvirus (HHV) CHPKs. We find that CHPKs can target key regulators of transcription and replication. The interaction with Cyclin A and associated factors is identified as a signature of β-herpesvirus kinases. Cyclin A is recruited via RXL motifs that overlap with nuclear localization signals (NLS) in the non-catalytic N termini. This architecture is conserved in HHV6, HHV7 and rodent cytomegaloviruses. Cyclin A binding competes with NLS function, enabling dynamic changes in CHPK localization and substrate phosphorylation. The cytomegalovirus kinase M97 sequesters Cyclin A in the cytosol, which is essential for viral inhibition of cellular replication. Our data highlight a fine-tuned and physiologically important interplay between a cellular cyclin and viral kinases.
Additional file 1 of Prognosis prediction models for post-stroke depression: a protocol for systematic review, meta-analysis, and critical appraisal
Creators: name: Zhou, Lu
name: Wang, Lei
name: Liu, Gao
name: Cai, EnLi
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer
Science Policy

description: Supplementary Material 1.
Gender inequality in the Science and Technology Universities of Ethiopia: policy representations and experiences of women
Creators: name: SIDELIL, Leul Tadesse
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 390201
subject: Education policy
classificationCode: 390303
subject: Higher education
classificationCode: 390406
subject: Gender, sexuality and education

description: In this thesis, I explore the problem of gender inequality in the STEM disciplines in higher education in Ethiopia. I do so by examining how gender inequality is represented in relevant policies directed to higher education vis-à-vis the lived experiences of women academics and students in two science and technology universities. To do so, I employ a critical policy analysis approach, alongside interviews and focus group discussions with government and university officials as well as women academics and students of Adama and Addis Ababa Science and Technology Universities. My data analysis is informed by three intersecting theoretical frameworks: the two-dimensional theory of gender justice (Fraser, 2003, 2013), the theory of gendered organisation (Acker, 1990, 2012) and the concept of institutional betrayal (Smith & Freyd, 2013, 2014).

The results provide strong support for the finding that gender inequality in the Science and Technology Universities is a multidimensional and complex problem. The problem is both numerical - that is, there is a gender disparity in favour of men; and insidious, in that there is a prevalent misrecognition of women which impedes their equitable participation and progression. The analysis also reveals that both the problem of gender inequality and the complex gendered institutional structure, practices and culture that underpin its perpetuation are misrepresented in policies directed to higher education. Because of this misrepresentation, the problem is either treated as an extraneous policy issue or it is narrowly and reductively construed as a mere problem of numerical gender disparity. Furthermore, implicating women as sources of the persistent problem, the policies characteristically attempt to `fix' women and not the institutional culture. Drawing on these findings this thesis argues that the policy misrepresentation contributes to the perpetuation of gender inequality by condoning the structural and institutional problems that (re)produce gender inequalities and, as a result, misdirects and forestalls much needed interventions to promote gender equality.
Predicting survival in anaplastic astrocytoma patients in a single-center cohort of 108 patients
Creators: name: Wahner, Helena C. W.
name: Träger, Malte
name: Bender, Katja
name: Schweizer, Leonille
name: Onken, Julia
name: Senger, Carolin
name: Ehret, Felix
name: Budach, Volker
name: Kaul, David
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Score
subject: Anaplastic astrocytoma
subject: Overall survival
subject: Glioma
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Current guidelines for the treatment of anaplastic astrocytoma (AA) recommend maximal safe resection followed by radiotherapy and chemotherapy. Despite this multimodal treatment approach, patients have a limited life expectancy. In the present study, we identified variables associated with overall survival (OS) and constructed a model score to predict the OS of patients with AA at the time of their primary diagnosis. Methods: We retrospectively evaluated 108 patients with newly diagnosed AA. The patient and tumor characteristics were analyzed for their impact on OS. Variables significantly associated with OS on multivariable analysis were included in our score. The final algorithm was based on the 36-month survival rates corresponding to each characteristic. Results: On univariate analysis, age, Karnofsky performance status, isocitrate dehydrogenase status, and extent of resection were significantly associated with OS. On multivariable analysis all four variables remained significant and were consequently incorporated in the score. The total score ranges from 20 to 33 points. We designated three prognostic groups: A (20–25), B (26–29), and C (30–33 points) with 36-month OS rates of 23%, 71%, and 100%, respectively. The OS rate at 5 years was 8% in group A, 61% in group B and 88% in group C. Conclusions: Our model score predicts the OS of patients newly diagnosed with AA and distinguishes patients with a poor survival prognosis from those with a greater life expectancy. Independent and prospective validation is needed. The upcoming changes of the WHO classification of brain tumors as well as the practice changing results from the CATNON trial will most likely require adaption of the score.
Additional file 2 of Prognosis prediction models for post-stroke depression: a protocol for systematic review, meta-analysis, and critical appraisal
Creators: name: Zhou, Lu
name: Wang, Lei
name: Liu, Gao
name: Cai, EnLi
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer
Science Policy

description: Supplementary Material 2.
Chesapeake Bay imaginaries: a human geography
Creators: name: Heckwolf, Leonard J.
Publisher: name: Maryland Shared Open Access Repository
Year: 2017

description: (M.A.) -- Towson University, 2017
description: Nature has been profoundly and increasingly impacted by the expansion of human society over time and space. While scholarly examination of the relationship between society and nature dates at least to ancient Greece, there is limited evolution in the ways we think about the natural environment. As human society reaches the point where nature is produced it finds itself at significant global risk as a result of its lack of appropriate consideration now that all parts of the earth are affected by human actions. This thesis examines this relationship both historically through a literature review and regionally by use of surveys and interviews to reveal insights into how a thin crosssection of society views nature. The literature review discloses the broad diversity of relations we have exhibited through time, until recent environmental conditions have required a more urgent examination of the relationship with nature. Surveys and interviews expose the perspectives participants embrace through consideration of their committed relationship with a particular expression of nature, the Chesapeake Bay of Maryland.
description: http://library.towson.edu/digital/collection/etd/id/58399
Design and evaluation of a data anonymization pipeline to promote Open Science on COVID-19
Creators: name: Jakob, Carolin E. M.
name: Kohlmayer, Florian
name: Meurers, Thierry
name: Vehreschild, Jörg Janne
name: Prasser, Fabian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: COVID-19
subject: Confidentiality
subject: Data Anonymization
subject: Pandemics
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The Lean European Open Survey on SARS-CoV-2 Infected Patients (LEOSS) is a European registry for studying the epidemiology and clinical course of COVID-19. To support evidence-generation at the rapid pace required in a pandemic, LEOSS follows an Open Science approach, making data available to the public in real-time. To protect patient privacy, quantitative anonymization procedures are used to protect the continuously published data stream consisting of 16 variables on the course and therapy of COVID-19 from singling out, inference and linkage attacks. We investigated the bias introduced by this process and found that it has very little impact on the quality of output data. Current laws do not specify requirements for the application of formal anonymization methods, there is a lack of guidelines with clear recommendations and few real-world applications of quantitative anonymization procedures have been described in the literature. We therefore believe that our work can help others with developing urgently needed anonymization pipelines for their projects.
Filologia mediolatina
Creators: name: Chiesa, Paolo
Publisher: name: Prassi Ecdotiche della Modernità Letteraria
Year: 2017
Subjects: riviste, filologia, filologia mediolatina

description: Filologia mediolatina, la rivista che mi trovo a dirigere, non è una rivista di nuova fondazione: il primo numero è uscito nel 1994, e da allora la pubbli- cazione è proseguita con continuità (quello del 2017 è il ventiquattresimo volume della serie). Lo sforzo per aprire una nuova rivista è naturalmente maggiore rispetto a quello di mantenerla attiva, come la spinta iniziale è maggiore della forza che si imprime a un corpo già in movimento; ma raccolgo volentieri lo stimolo proposto da PEML, spiegando le ragioni per le quali questa esperienza mi sembra avere ancora un suo senso e una sua attualità.

http://www.fefonlus.it/index.php?option=com_k2&view=item&layout=item&id=518&Itemid=220&lang=it
description: Prassi Ecdotiche della Modernità Letteraria, N. 2 (2017)
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma
Creators: name: Helmsauer, Konstantin
name: Valieva, Maria E.
name: Ali, Salaheddine
name: Chamorro González, Rocío
name: Schöpflin, Robert
name: Röefzaad, Claudia
name: Bei, Yi
name: Dorado Garcia, Heathcliff
name: Rodriguez-Fos, Elias
name: Puiggròs, Montserrat
name: Kasack, Katharina
name: Haase, Kerstin
name: Keskeny, Csilla
name: Chen, Celine Y.
name: Kuschel, Luis P.
name: Euskirchen, Philipp
name: Heinrich, Verena
name: Robson, Michael I.
name: Rosswog, Carolina
name: Toedling, Joern
name: Szymansky, Annabell
name: Hertwig, Falk
name: Fischer, Matthias
name: Torrents, David
name: Eggert, Angelika
name: Schulte, Johannes H.
name: Mundlos, Stefan
name: Henssen, Anton G.
name: Koche, Richard P.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Acetylation
subject: Base Sequence
subject: Cell Line, Tumor
subject: Chromosomes, Human
subject: DNA Methylation
subject: DNA, Circular
subject: Enhancer Elements, Genetic
subject: Epigenesis, Genetic
subject: Kaplan-Meier Estimate
subject: N-Myc Proto-Oncogene Protein
subject: Nanopore Sequencing
subject: Neuroblastoma
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: MYCN amplification drives one in six cases of neuroblastoma. The supernumerary gene copies are commonly found on highly rearranged, extrachromosomal circular DNA (ecDNA). The exact amplicon structure has not been described thus far and the functional relevance of its rearrangements is unknown. Here, we analyze the MYCN amplicon structure using short-read and Nanopore sequencing and its chromatin landscape using ChIP-seq, ATAC-seq and Hi-C. This reveals two distinct classes of amplicons which explain the regulatory requirements for MYCN overexpression. The first class always co-amplifies a proximal enhancer driven by the noradrenergic core regulatory circuit (CRC). The second class of MYCN amplicons is characterized by high structural complexity, lacks key local enhancers, and instead contains distal chromosomal fragments harboring CRC-driven enhancers. Thus, ectopic enhancer hijacking can compensate for the loss of local gene regulatory elements and explains a large component of the structural diversity observed in MYCN amplification.
Research Data for Is SARS-CoV-2 viral load a predictor of mortality in COVID-19 acute respiratory distress syndrome patients?
Creators: name: Dogan, Lerzan
name: Allahverdiyeva, Aytaj
name: Önel, Mustafa
name: Meşe, Sevim
name: Saka Ersin, Esra
name: Anaklı, İlkay
name: Sarıkaya, Zeynep Tuğçe
name: Zengin, Rehile
name: Gucyetmez, Bulent
name: Yurtturan Uyar, Neval
name: Özcan, Perihan Ergin
name: Kocagöz, Ayse Sesin
name: Uysal, Hayriye Kırkoyun
name: Akinci, İbrahim Ozkan
name: Ağaçfidan, Ali
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery

description: Research Data for Is SARS-CoV-2 viral load a predictor of mortality in COVID-19 acute respiratory distress syndrome patients? by Lerzan Dogan, Aytaj Allahverdiyeva, Mustafa Önel, Sevim Meşe, Esra Saka Ersin, İlkay Anaklı, Zeynep Tuğçe Sarıkaya, Rehile Zengin, Bulent Gucyetmez, Neval Yurtturan Uyar, Perihan Ergin Özcan, Ayse Sesin Kocagöz, Hayriye Kırkoyun Uysal, İbrahim Ozkan Akinci and Ali Ağaçfidan in Journal of International Medical Research
Additional file 3 of Prognosis prediction models for post-stroke depression: a protocol for systematic review, meta-analysis, and critical appraisal
Creators: name: Zhou, Lu
name: Wang, Lei
name: Liu, Gao
name: Cai, EnLi
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer
Science Policy

description: Supplementary Material 3.
The development of an augmented reality robot programming application
Creators: name: ZHANG, Fengxin
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 400707
subject: Manufacturing robotics
classificationCode: 460708
subject: Virtual and mixed reality

description: Industrial robots have been traditionally programmed using the teaching pendant, while offline programming methods are getting increasingly popular in recent years. Although the above two methods are widely-used in the industry, they both have certain disadvantages. For instance, the teaching pendant method requires shutting down the production line during the programming process, while offline programming method requires 3D CAD models of both the robot and the workpiece. Unfortunately, it is not always possible to have the CAD models of workpiece, especially in the MRO (maintenance, repair and overhaul) sector where objects have undergone different damages. In this research, a new augmented reality (AR) application which alleviates the aforementioned problems was developed for robot programming purposes based on commercial AR software. The production line does not need to be stopped, and 3D models of the workpiece are also not required. Users can see the actual object and the virtual robot in an AR environment by wearing wearable AR devices such as Microsoft Hololens. The virtual robot will then be programmed to reach the target points on the actual workpiece, while avoiding collisions or singularities. The application is created using commercially available AR software, with the addition of JavaScript code. The use of commercially available software allows an easier sharing and widespread adoption of the application. Research questions to be answered in this project include how robot model can be manipulated in AR environment, how AR technology can be used to create robot codes, and how accuracy can be improved. The research output is an AR robot programming application which is developed using only standard commercial software, which is user friendly and can be downloaded by users around the world.
Networks of innovation: measuring, modelling and enhancing innovation in surgery
Creators: name: Garas, Georgios
Publisher: name: Imperial College London
Year: 2019

description: The rate of innovation occurring in surgery is beyond our systemic capacity to quantify, with several methodological and practical challenges. The existing paucity of surgical innovation metrics presents a global healthcare problem especially as surgical innovations become increasingly costlier at a time when healthcare provision is experiencing a radical transformation driven by pressures to reduce costs, an ageing population with ever-increasing healthcare needs and patients with growing expectations. This thesis aims to devise a novel, quantitative, network-based framework that will permit modelling and measuring surgical innovation to add the most value to patient care. It involves the systematic, graphical and analytical assessment of surgical innovation in a way that has never been done before. This is based on successful models previously applied in the industry with advanced analytical techniques derived from social science (network analysis). In doing so, it offers an exciting new perspective and opportunity for understanding how the innovation process originates and evolves in surgery and how it can be measured in terms of value and virality, a priority for the NHS, RCS, Imperial and the wider surgical community. The ability to measure value and rank innovations is expected to play a fundamental role in guiding policy, strategically direct surgical research funding, and uncover innovation barriers and catalysts. This will ensure participation in the forefront of novel surgical technology and lay the scientific foundations for the development of improved healthcare models and services to enhance the quality of healthcare delivered.
Arbeitskarte Geographische Namen 1:100 000 Schirmacherseenplatte/Schirmacheroase, Antarktis
Creators: name: Bennat, Heinz
Publisher: name: Institut für Angewandte Geodäsie (Now: Bundesamt für Kartographie und Geodäsie), Frankfurt am Main
Year: 1998
Subjects: Antarctica
Geographical names
Schirmacherseenplatte
Schirmacheroase
Nivlisen
Tronstadhallet
skaly Instituta Geologii Arktiki
Lingetoppane

description: Worksheet of Norwegian, Russian and German geograpical names, GeoMaud-Expedition 1995/96; All German place-names are listed that were clearly relatable and initially assigned to geographical objects during their discovery in 1938/39; The topography is coarsely portrayed by delimiting rocks and moraines and by 200 m contours;Scale: 1:100000;Projection: Polar Stereographic; Bounding Box: POLYGON  ((11 -70.5, 12.5 -70.5, 12.5 -71.1667, 11 -71.1667, 11 -70.5)); Datum: GRS80
Spatial-temporal air pollution models for national-scale health studies
Creators: name: Wang, Weiyi
Publisher: name: Imperial College London
Year: 2020

description: Air pollution exposure assessment is fundamental to establish the associations between air pollution and health outcomes. In the recent decade, exposure models have been widely used to assess the long-term effects of air pollution. Studies analysing the short-term effects, however, are still relying on measurements obtained from routine monitoring network. The aim of this thesis is to develop spatially resolved daily and annual air pollution models using land use regression (LUR) techniques that can be applied in air pollution epidemiological studies in Great Britain. The first part of the thesis developed national air pollution exposure models NO2, PM2.5, PM10 and O3. The spatial models followed a traditional land use regression technique, and the spatio-temporal models used a generalised additive mixed model framework (GAMM). The predictors include geographic information system (GIS)-derived land use variables and estimates from a chemical transport model (CTM). The second part demonstrated an application of daily estimates in a case-crossover design to assess the health effects of short-term exposure at the individual level. Overall, the hybrid approach incorporating land use information and CTM estimates improved model performance compared to traditional LUR, and produced more accurate long-term exposure estimates. The GAMM framework integrating land use variables and daily CTM estimates successfully captured local space-time variability over a large geographic domain. Using the modelled daily NO2 concentrations in a case-crossover design, NO2 was found to be associated with emergency hospital admissions for both asthma and other respiratory diseases. The short-term and long-term exposure models developed in this thesis have great potential in reducing exposure misclassification in epidemiological studies.
Additional file 1 of Application of personalized templates in minimally invasive management of coronal dens invaginatus: a report of two cases
Creators: name: Li, Mingming
name: Wang, Guosong
name: Zhu, Fangzhi
name: Jiang, Han
name: Yang, Yingming
name: Cheng, Ran
name: Hu, Tao
name: Zhang, Ru
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Supplementary Material 1.
Optimising the identification of acute deterioration and sepsis through digital technology
Creators: name: Joshi, Meera
Publisher: name: Imperial College London
Year: 2019

description: Sepsis is a global health concern with a high mortality. For every hour’s delay in sepsis treatment, mortality increases by 7.6%. Vital sign changes are used to detect alterations in a patient’s physiology and detect deterioration. Novel wearable sensors, which measure vital signs continuously, may identify unwell patients and sepsis sooner. We aimed to determine if such sensors could reliably identify unwell patients and those with sepsis sooner. A sensor was selected which measures multiple vital signs simultaneously. The sensor measures heart rate, respiratory rate and temperature every 2 minutes. Sensor and nursing ward data were compared, patient data and staff feedback was collected. A 500-patient study is complete with admitted patients wearing the sensor in additional to standard clinical monitoring. Comparisons between sensor readings and ward observations taken by nurses were made. A comparison of sensor time windows for alert generation was made and the 10 minute window selected. The correlation coefficient between Sensium data and ward observation data for Heart Rate (HR) was 0.79 (p=0.0001) and a mean difference of less than 3 beats per minute. The correlation coefficient between Sensium data and ward observation data for Respiratory Rate (RR) was 0.3 (p=0.0001) and a mean difference of less than 2 breaths per minute. The correlation coefficient between Sensium data and ward observation data for temperature was 0.43 (p=0.0001) and a mean difference of less than 0.5° C. In 82% of cases of HR and 81% of RR the sensor was faster than ward observations in time to detection. Patient feedback was positive (453 questionnaires analysed) with 86% agreeing to wear the sensor again and 85% agreeing it was comfortable. Staff groups were interviewed; feedback was positive with problems in current monitoring highlighted. Wearable sensors may cause a paradigm shift in future patient monitoring with safer, smarter wards.
Supplemental Material - Likely Electromagnetic Foundations of Gender Inequality
Creators: name: León, Federico R.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Anthropology
subject: FOS: Sociology
subject: 200299 Cultural Studies not elsewhere classified
subject: FOS: Other humanities

description: Supplemental Material for Likely Electromagnetic Foundations of Gender Inequality by Federico R. León in Cross-Cultural Research
Humans in the loop: incorporating occupant behaviour in building performance simulations
Creators: name: MARSCHALL, Max
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 330105
subject: Architectural science and technology

description: In this thesis I argue for the need to consider the effects of occupant behaviour on the environmental sustainability of buildings, and propose and test novel methods to incorporate this behaviour in building performance simulations during the architectural design process.
Regulatory mechanisms in biochemical signalling pathways: From AXL signalling in cancer to feedback regulation in biochemical pathways
Creators: name: Cai, Junjun
Publisher: name: Imperial College London
Year: 2020

description: Cellular signalling transduction has been studied using experimental, computational and theoretical approaches. The regulation of signal transduction in organisms is a key systems aspect which determines the pathway behaviour and function. However, due to the lack of systematic engineering-based understanding of cellular signalling behaviour and pathways, the underlying design principles and potential controlling methods of cellular signal transductions and correlated pathological states in a large number of cellular signalling pathways still remain uncharted. This thesis focusses on two studies involving regulation of signal transduction. The first study focusses on feedback regulation, specifically multiple feedback regulation. In order to gain an insight into regulatory effects mechanisms of multiple feedback pathways in regulating cellular signal transduction, generic models of enzymatic modification and substrate modification signalling cascades were built and studied with different types and different architectures of the feedback regulatory pathways. Hereby, an understanding and synthesis of how the system output responded to different structures of single and double feedback regulations in both classes of signalling pathways was characterised. Building on this, multiple feedback regulation in open systems, as well as feedback regulation in bacterial two component systems were also studied. The other study focussed on membrane level regulation of signalling in ovarian cancer. Cancer has been recognised as a serious disease for centuries, it is primarily triggered by misfunctions of cellular signal transduction. We focus here on AXL signalling in ovarian cancer to understand this pathological state in cells, the receptor tyrosine kinase AXL and its relating membrane and cytosol signalling pathways, during the metastasis of tumorous cells, were studied and analysed computationally, building on and collaborating with experimental work. A key ingredient here is the membrane-level compartmentalization of phosphatases involved in the regulation. We built a systems framework to analyse the interplay of key factors affecting AXL signalling. This also reveals underlying design principles for the regulation of AXL signalling which are more broadly applicable. Finally, some basic analysis of feedback regulation building on this was also studied.
Additional file 2 of Application of personalized templates in minimally invasive management of coronal dens invaginatus: a report of two cases
Creators: name: Li, Mingming
name: Wang, Guosong
name: Zhu, Fangzhi
name: Jiang, Han
name: Yang, Yingming
name: Cheng, Ran
name: Hu, Tao
name: Zhang, Ru
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Supplementary Material 2.
Earnings management, investors’ trading behaviour, cost of equity capital, and risk-taking: evidence from banks in Asia-Pacific region
Creators: name: VO, Nguyen
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 350101
subject: Accounting theory and standards
classificationCode: 350105
subject: Management accounting
classificationCode: 350299
subject: Banking, finance and investment not elsewhere classified

description: The issue of earnings management, a use of accounting techniques to manipulate reported earnings, though widely discussed in the literature, still remains the concern of investors, researchers and policy makers as earnings is a primary source of firm's information. The main thrust of this research is to investigate the impacts of bank earnings management on investors' trading behaviour when investing in bank stocks, banks' cost of equity capital and bank risk-taking behaviour. This study also examines the roles of bank accounting regulations, enforcement regimes, institutional quality and IFRS adoption on the associations between bank earnings management and investors' trading behaviour as well as banks' cost of equity capital. This research focuses on the Asia-Pacific banking sector, the world's largest regional banking market, because banks in this region are facing rising risk and capital cost. In addition, Asia Pacific offers a fruitful context for this research because countries in this region have a diversity of bank regulations, enforcement regimes, institutional environment and IFRS adoption. Using a sample of 250 commercial banks in 13 Asia-Pacific countries and territories over a period of 2002-2017, pooled Ordinary Least Squares, Fixed Effects and System Generalised Method of Moments Models are employed to analyse the data. The study finds that bank earnings management has significant impacts on bid-ask spread, banks' cost of equity and bank risk-taking. The results imply that investors can detect bank earnings management and use this information to obtain profits in stock markets, plus, investors demand compensation when investing in banks where earnings management exists. In addition, earnings management induces bank managers to take on more risk to maintain profitability and compensation. This study also sheds light on the signalling effects of bank accounting regulations, enforcement regimes, institutional quality and IFRS adoption in guiding investors' behaviour and expectation of return in response to bank earnings management. Furthermore, the study extends the 'search for yield' argument to the practices of accounting manipulation as an incentive to take risk of banks.
sj-docx-1-chl-10.1177_17475198221141979 – Supplemental material for Thermal and thermo-oxidative stability of a series of palladium and platinum ferrocenylamine sulfides and selenides
Creators: name: Ali, Hussein M
name: Ali, Isra H
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, sj-docx-1-chl-10.1177_17475198221141979 for Thermal and thermo-oxidative stability of a series of palladium and platinum ferrocenylamine sulfides and selenides by Hussein M Ali and Isra H Ali in Journal of Chemical Research
Ionosphere Sounding Data Processing Information System (Isdpis) – Basics, Potentials And Perspective
Creators: name: Bajcetic, Jovan
name: Trikoš, Mladen
name: Tot, Ivan
Publisher: name: Zenodo
Year: 2018
Subjects: data processing
visualization
ionosphere
disturbance
data acquisition

description: Big data proper handling drives the possibility for real-time detection and visualization of complicated long-lasting, as well as short, transient events. Among other applications, the one that is rapidly getting in focus latest years is definitely Space weather. The effects on the atmosphere, as well as the ionosphere, as one of its regions, are driven mainly by Sun – the electromagnetic and particle emissions coming from the active regions. This paper gives the overview of the developed set of Python scripts and the MySQL database which as a whole give the complete information system solution for the detection and visualization of the recorded ionosphere sounding radio signal sudden amplitude variation induced by sources of Space weather disturbances.
Additional file 1 of Phylogenetic analysis and antigenic epitope prediction for E6 and E7 of Alpha-papillomavirus 9 in Taizhou, China
Creators: name: Yuan, Haobo
name: Yan, Ziyi
name: Gan, Jun
name: Di, Xinghong
name: Qiu, Yi
name: Xu, Huihui
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 1.