cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Putting research to the test: Implementing selective dry cow therapy on farms across New York State
Creators: name: Potter, Tracy
name: Forrestal, Amber
name: Capel, Michael
name: Nydam, Daryl
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: SDCT
dry period
mastitis
algorithm

description: Selective dry cow therapy (SDCT) has been shown to be an ef­fective way of using antimicrobials judiciously on dairy farms while decreasing treatment costs and maintaining herd health. However, adoption of the practice has been slow in the U.S. In order to improve the adoption of this practice in New York State, we formed a team of veterinarians to help interested dairy producers and their herd veterinarians to implement SDCT successfully. Not all farms are a good fit for SDCT. An in-depth discussion between the herd veterinarian and farm stakeholders before adoption is necessary. This discussion should include current practices, data available to make the selection process, best practices for dry off and dry-pen man­agement, and how to monitor progress going forward. Our team enrolled 24 farms over the course of a year. Seventeen out of 24 farms are still using SDCT at the time of publishing. A variety of SDCT methods were used, and on average, herds decreased dry cow antibiotic use by 53%. The metrics we used to monitor herd infection dynamics before and after SDCT included aver­age monthly somatic cell count, fresh cow mastitis incidence, average herd prevalence of a high first test, average herd preva­lence of subclinical infection, average new infection risk, and cure risk. For all but a few herds, 95% confidence intervals overlapped for all outcomes before and after starting SDCT and differences were relatively small. In our experience, SDCT, if employed on the right farm, is an effective way to use antibiot­ics judiciously at dry off without disrupting herd health.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
MOESM2 of A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei
Creators: name: Lei, Chao
name: Wang, Jingzhi
name: Liu, Yuanyuan
name: Liu, Xinqiang
name: Zhao, Guoping
name: Wang, Jin
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 2: Figure S2. Transcriptional analysis of rifQ in rifQ+ and S699. The assay was performed at three different time points, i.e., 24Â h, 48Â h and 72Â h. rpoB was used as an internal control.
MOESM3 of A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei
Creators: name: Lei, Chao
name: Wang, Jingzhi
name: Liu, Yuanyuan
name: Liu, Xinqiang
name: Zhao, Guoping
name: Wang, Jin
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 3: Figure S3. Diagram of the rifamycin biosynthesis cluster. The rif cluster consisted of 10 operons, which were indicated by solid lines, and direction of the operons was indicated by arrows.
German Politics and the 'Jewish Question', 1914-1919
Creators: name: Linares, Lucia Juliette
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Imperial Germany
Jewish Question
Nation-state
Citizenship
Nationality
Minority rights
Weimar Republic
Paris Peace Conference
First World War
Zionism

description: The First World War confronted German politicians with a range of unprecedented, vital questions in the spheres of domestic as well as foreign policy. As the fortunes of war shifted, so did borders, populations and national allegiances. In a period of acute and almost constant political crisis, the German government faced issues concerning citizenship, minority rights, religious identity, nationhood and statehood. My dissertation analyses these issues through the prism of the so-called 'Jewish Question'. The Jewish Question, I contend, casts important new light on Germany’s difficult path towards a new democratic and pluralistic constitution in 1919. Jewish questions revealed the paradoxes of German state-building and the difficulties of breaking down older forms of corporate identity for the sake of national-cultural homogeneity. My principal aim in this dissertation is to offer a novel interpretation of the role that the 'problem' of German Jewry played in the political debates and decisions that paved the way for the Weimar Republic. The relevant historiography still tends to read the Jewish Question with hindsight, that is, in the context of the Holocaust and from a social or cultural historical perspective. While it does not ignore the short- and long-term effects the Jewish Question had on the rise of German antisemitism, my dissertation stresses its contingency and ambivalence. It offers the first sustained examination of the ways in which questions about German-Jewish citizenship and religious as well as national identity shaped the politics of the last Imperial government and influenced the processes of parliamentarisation and democratisation in the final years of the war. The Jewish Question, I argue, affords revealing new perspectives on the difficult birth of the Weimar Republic.
description: Doctoral Scholarship, HM Government of Gibraltar Leo Baeck Fellow, Studienstiftung des deutschen Volkes
MOESM4 of A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei
Creators: name: Lei, Chao
name: Wang, Jingzhi
name: Liu, Yuanyuan
name: Liu, Xinqiang
name: Zhao, Guoping
name: Wang, Jin
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: Plant Biology
subject: Computational Biology

description: Additional file 4: Figure S4. Transcriptional analysis of genes in rif cluster in different strains. S699, the wild type; Î rifQ, the rifQ null mutant. At least one gene was chosen from each operon to characterize the transcriptional profile of the operon (ref to Figure S4), and rpoB gene was used as the internal control. All the transcription analyses were performed at both the early- and middle-exponential phases. Cycles for PCR amplification of each gene were labelled. Except rifP, which transcription increased in Î rifQ, the transcription of all other tested genes showed moderate decrease at the early-exponential phase, indicating that RifQ might be involved in positive regulation of the transcription of these genes (or operons). However, more experiments may need to be done in future to uncover the exact role of RifQ in regulation of rif cluster. In addition, this moderate regulation mediated by RifQ disappeared when strains reached the middle-exponential phase.
What have we learned about milk quality and udder health in automatic milking systems?
Creators: name: Kelton, David
name: Hand, Karen
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023

description: The adoption of automatic milking systems (AMS) continues to increase across North America. An analysis of milk quality data from more than 3,000 dairy farms in Ontario, Canada sug­gests that while AMS herds have a slightly higher average raw bacteria count and higher risk of incurring a bacterial or freez­ing point penalty, the bulk tank somatic cell count is similar among farms using pipeline, parlor and AMS systems. These results indicate that farms milking with AMS can produce milk of similarly high quality as those milking with conventional milking systems (CMS). A panel of individuals shared their opinions about advantages and disadvantages of AMS and CMS, with a number of AMS attributes appearing in both lists, sug­gesting that the perception will depend on the context and the attributes of the AMS.  
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Experimental and numerical investigation of a static mixer for the production of biodiesel
Creators: name: Leong, Jason Yu Chuan
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Currently, unless aided by subsidies or some form of government directive, biodiesel cannot compete against regular petro diesel because of lower pump costs. Attempting to lower production costs of biodiesel would be helpful in narrowing the price gap between these two competing fuels. The production of biodiesel involves mixing organic oil and a short chain alcohol which are not miscible in the early stages of reaction. The interfacial area between the two phases is believed to strongly affect the reaction rate leading to the development of numerous methods for the dispersion of short chain alcohol in organic oil. One such method is through the use of a static mixer which is a motionless inline pipe mixer with specially shaped baffles used to promote mixing. This study investigated the effectiveness of a Kenics static mixer as a dispersion tool in biodiesel production with methanol as the short chain alcohol and palm oil as the organic oil. This was performed by measuring the droplet sizes of methanol dispersed in palm oil for different flow parameters, namely the mixer length and flow rate. The moderately high concentration of methanol (20% volume fraction) presented an additional level of complexity in the experimental investigation and necessitated the development of a suitable droplet measurement technique which consisted of a modified borescope attached to a digital camera and coupled with a strobe light source. Experimental results showed that the static mixer was certainly an effective mixer, outperforming the conventional agitated vessel design seen in most biodiesel production plants but was not as effective as ultrasonic emulsifiers although this method requires the highest energy input. The experimental study was complemented by a parallel numerical investigation which was performed using the commercial computational fluid dynamics (CFD) code ANSYS-FLUENT. To account for the droplet size evolution, the CFD simulations were coupled to a population balance model with the appropriate droplet breakage and coalescence models. There was reasonable agreement between experimental results and numerical simulations. In addition, numerical simulations predicted that the static mixer was the most efficient mixer when accounting both droplet size reduction and energy requirements. The findings of this study suggest that the Kenics static mixer is an efficient mixer. It is, therefore, worth investigating the use of the Kenics static mixer as a continuous reactor for the production of biodiesel without any rotating parts and possibly at room temperature. This would present a novel design which could be attractive in achieving quality product at low operating cost.
Das Berliner Album amicorum von Aernout van Buchell
Publisher: name: Utrecht University
Year: 2020
Subjects: subject: Humanities - History and archaeology (6.1)
subject: Humanities - Languages and literature (6.2)
subject: Humanities - Art (arts, history of arts, performing arts, music) (6.4)
subject: album amicorum
subject: Reformatie
subject: zestiende eeuw
subject: tekeningen
subject: Latijn
subject: Reformation
subject: sixteenth century
subject: drawings
subject: Latin

description: Transcriptie en vertaling in het Nederlands van Berlijn. Kunstbibliothek Staatliche Museen Preussischer Kunstbesitz, Lipperheidesche Kostümbibliothek, Lipp. O Z3 (Album amicorum van Aernout van Buchell), met commentaren in het Nederlands en Duits.
Transcription and translation into Dutch of Berlin. Kunstbibliothek Staatliche Museen Preussischer Kunstbesitz, Lipperheidesche Kostümbibliothek, Lipp. O Z3 (Album amicorum of Aernout van Buchell), with comments in Dutch and German.
Microbiology, MALDI-TOF, Microbiome and more: How to understand and use diagnostic tests to improve udder health
Creators: name: Ruegg, Pamela L.
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: mastitis
dairy
udder health
milk quality

description: Determining an appropriate intervention after intramammary infection depends on an accurate diagnosis, but there are a bewildering variety of tests that can be used to detect mastitis and determine etiology. Traditional microbiological tests rely on phenotypic and/or biochemical methods to identify bacteria but more accurate identification is achieved using newer meth­ods such as Maldi-Tof which often results in a confusing array of unfamiliar bacterial names. Non-culture-based methods such as PCR are increasingly affordable but have both strengths and limitations that need to be acknowledged when making management decisions. Other technologies, such as determina­tion of the milk microbiome have unfamiliar terminology and methods that require explanation before used to make deci­sions about handling mastitis cases. In this presentation the methods and clinical implications of using traditional microbi­ology and farm based or laboratory based molecular methods to diagnose mastitis will be discussed with emphasis on practi­cal decision making.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Nutrition and management implications of the U.S. dairy 2050 environmental stewardship goals and net zero initiative for bovine practitioners
Creators: name: Tricarico, Juan M.
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: GHG emissions
enteric methane
mitigation options

description: U.S. dairy collectively commits to achieve greenhouse gas neu­trality, optimize water use while maximizing recycling, and improve water quality by optimizing utilization of manure and nutrients by 2050. The farm and field strategy to achieve these goals is termed the Net Zero Initiative. Enteric methane miti­gation is a key area of focus for the 2050 Environmental Stew­ardship Goals and the Net Zero Initiative that is relevant to the dairy management and nutrition fields. Bovine practitioners have various critical roles to support the dairy value chain in making progress toward the 2050 environmental stewardship goals due to their focus on promoting cattle health, welfare and productivity. Bovine practitioners will contribute greatly to enteric methane mitigation and the evaluation of nutritional interventions to mitigate methane. Therefore, bovine practitio­ners need to better understand and articulate the environmen­tal value animal and feed management options provide in addi­tion to nutritional contributions, health status and cost savings.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
MOESM5 of A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei
Creators: name: Lei, Chao
name: Wang, Jingzhi
name: Liu, Yuanyuan
name: Liu, Xinqiang
name: Zhao, Guoping
name: Wang, Jin
Publisher: name: figshare
Year: 2018
Subjects: subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 5: Figure S5. Primer extension analysis of rifP TIS. Primer rifP-pe1 was used and around 500-nt reverse transcript was observed via the ABI 3130xl capillary electrophoresis. Only one single peak was observed, demonstrating the high integrity of the rifP transcript. Based on this information, rifP-pe2 primer was further designed and the primer extension results employing rifP-pe2 could be found in Fig.Â 2b.
MOESM6 of A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei
Creators: name: Lei, Chao
name: Wang, Jingzhi
name: Liu, Yuanyuan
name: Liu, Xinqiang
name: Zhao, Guoping
name: Wang, Jin
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Additional file 6: Figure S6. Purification of recombinant His-tagged RifQ protein and measurement of its molecular weight (MW). (a) Purification of His-tagged RifQ via the Ni–NTA column, following the manufacturer’s instructions. Samples collected at different steps were analyzed by SDS-PAGE and stained by coomassie blue, employing the protein marker (Thermo Fisher Scientific; Cat. No. 26616). (b)  Diagram of the size exclusion chromatography analysis of RifQ, using the Low Molecular Weight (LMW) Kit (GE Healthcare Life Sciences).
Literature in Vietnamese tertiary English programs: perspectives and practice
Creators: name: Truong, Thi My Van
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: English is now a dominant foreign language in Vietnam and exerts a powerful influence on various aspects of Vietnamese society. With the power and influence of English, Vietnamese learners have changing perceptions about the purposes of language learning. In tertiary English-major programs, the status of literature has been contested and challenged and priority has been given to subjects that directly facilitate learners’ careers such as Business English courses. In this context, the teaching and learning of literature are both at risk and controversial. This study is set in the Vietnamese English as a second language (EFL) context. By investigating teacher and student perspectives on teaching and learning literature in the tertiary English-major program, this study examines the role that literature plays in tertiary ELT in Vietnam. The study analyses the pedagogy used and student responses to this, then looks at the implications for pedagogy and the status of literature in a global economy where English is primarily the language of business. The study follows a qualitative research tradition and consists of a case study of four Vietnamese teachers and 12 students of English in one Vietnamese EFL tertiary program. Data generation included pre-course and post-course in-depth interviews of teachers and students, class observations, the collection of student writing during the courses, textbooks and syllabi of the courses, and the curriculum of the program. Discourse analysis and text analysis were used to interpret the data based on the issues raised in the research questions. The findings of the study show that, despite a recognition of the value of literature by both teachers and language learners, the status of literature in the program was at risk due to institutional constraints and learners’ practical focus on careers using English. The study reveals that the literature class provided many opportunities for communicative language teaching (CLT) and learning, especially via the use of Reader Theatre. However, in terms of critical thinking and deeper text analysis, the use of CLT in the classes in the study was hindered by a number of contextual factors, in particular class size, time limits, inflexible class seating, and teachers’ limited expertise in generating interaction among students. The literature pedagogy fostered in most students an awareness of the value of literature to personal development and a knowledge of culture and language, yet the pedagogy could be improved to be more engaging to learners, to enable them to develop communicative competence, literary competence, critical thinking skills and to broaden perspectives on themselves, the world and the status of English as a global language.
MULTIMODAL GRADIENTS UNIFY LOCAL AND GLOBAL CORTICAL ORGANIZATION
Creators: name: Wang, Yezhou
name: Eichert, Nicole
name: Paquola, Casey
name: Rodriguez-Cruces, Raul
name: DeKraker, Jordan
name: Royer, Jessica
name: Cabalo, Donna Gift
name: Auer, Hans
name: Ngo, Alexander
name: Leppert, Ilana
name: Tardif, Christine L.
name: Rudko, David A.
name: Amunts, Katrin
name: Smallwood, Jonathan
name: Evans, Alan C.
name: Bernhardt, Boris C.
Publisher: name: Forschungzentrum Jülich
Year: 2024

description: doi:10.1101/2024.03.11.583969
description: Specialization of brain areas and subregions, as well as their integration into large-scale networks are key principles in neuroscience. Consolidating both local and global cortical organization, however, remains challenging. Our study developed a new approach to map global cortex-wise similarities of microstructure, structural connectivity, and functional interactions, and integrate these patterns with maps of cortical arealization. Our analysis combined repeated high-field in-vivo 7 tesla (7T) Magnetic Resonance Imaging (MRI) data collected in 10 healthy adults with a recently introduced probabilistic post-mortem atlas of cortical cytoarchitecture. We obtained multimodal eigenvectors describing cortex-wide gradients at the level of microstructural covariance, structural connectivity, and intrinsic functional interactions, and then assessed inter- and intra-area differences in cortex-wide embedding based on these multimodal eigenvectors. Inter-area similarities followed a canonical sensory-fugal gradient, with primary sensorimotor cortex being the most distinctive from all other areas, while paralimbic regions were least distinctive. This pattern largely corresponded to functional connectivity variations across different tasks collected in the same participants, suggesting that the degree of global cortical integration mirrors the functional diversity of brain areas across contexts. When studying heterogeneity within areas, we did not observe a similar relationship, despite overall higher heterogeneity in association cortices relative to paralimbic and idiotypic cortices. The results were replicated in a different dataset. Our findings highlight a close coupling between cortical arealization and global cortical motifs in shaping specialized versus integrative human brain function.
MOESM7 of A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei
Creators: name: Lei, Chao
name: Wang, Jingzhi
name: Liu, Yuanyuan
name: Liu, Xinqiang
name: Zhao, Guoping
name: Wang, Jin
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 7: Figure S7. Schematic diagram of the rifP promoter region. TIS was obtained by primer extension assays (ref to Fig.Â 2), and was indicated by a curved arrow. The RifQ-protected region was underlined and the proposed RifQ-binding sites were boxed. The translation start codon of rifQ was shown in bold.
Deregulated gp130 signalling contributes to lung tumourigenesis and the development of cancer-related cachexia
Creators: name: Miller, Alistair
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Lung cancer is the leading cause of cancer death in Australia and worldwide, and is frequently associated with the devastating paraneoplastic syndrome of cachexia. While recent discoveries in the molecular foundations of lung cancer have produced specific, directed therapies with substantial benefit, these are effective in only a small proportion of patients with adenocarcinomas that demonstrate specific molecular characteristics. New therapies are desperately needed and the search for new molecular targets requires models with good translational potential. The potent immunomodulatory cytokine interleukin (IL)-6 has been linked with the development of lung cancer as well as cachexia, and presents a promising specific target in anti-cancer therapy. This thesis addresses the question of the role of IL-6 by utilising the FF mouse which, by virtue of a “knock in” substitution within the IL-6 family co-receptor gp130, displays endogenously elevated IL-6. As a consequence of this mutation, the FF mouse displays hyper-activation of the latent transcription factor STAT3 in the absence of gp130-driven PI3K/Akt and MAPK signalling. Importantly, STAT3, PI3K/Akt and MAPK have all been implicated in lung cancer development and the development of cachexia. Initial characterisation of the FF mouse lung demonstrated substantial pulmonary inflammation that is largely composed of B220+ cells. This inflammation is driven by IL-6 through STAT3 but not STAT1. Following this characterisation the FF mouse was used in two separate well-established lung cancer models; a cigarette carcinogen (NNK) model and a genetic (KrasG12D) model. In the cigarette carcinogen model there was a significant reduction in tumour number and size in FF mice, which appeared to be largely independent of STAT3. The difference seen is contributed to by the loss of gp130-driven PI3K/Akt and/or MAPK signalling as evidenced by upregulation of tumour suppressor genes and down-regulation of oncogenes in the FF mouse, downstream of both PI3K/Akt and MAPK. In the genetic model the key finding was of weight loss and early mortality in the absence of a significant change in tumour load in the FF:KrasG12D mice. Both the weight loss and early mortality were abrogated by genetically normalising STAT3 activation and ablating IL-6. Importantly, we also identified IL-6 trans-signalling as the signalling modality responsible for the cachexia by rescuing the weight loss using a monoclonal Ab targeting in the sIL6R.
The Ruminant Farm Systems Model: A decision-support tool for whole farm efficiency and sustainability
Creators: name: Reed, Kristan F.
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: environmental footprints
, decision-support tools
greenhouse gas emissions

description: Sustainable dairy production requires methods to quantify the environmental footprint of dairy farms that can inform management decisions. Impact inventories can provide some insight for policy, but are not suitable to inform decisions at the farm level. Decision-support tools like the Ruminant Farm Systems (RuFaS) model represent farm management and esti-mate environmental impacts with enough detail and flexibility to compare the effect of management practices and guide farm management decisions. For example, RuFaS can be used to compare the environment impacts of reproduction protocols. The RuFaS model estimates that improving the reproductive performance of a 1,000-cow herd from a low performance to a baseline performance scenario reduces manure and enteric methane production and the emissions intensity of milk pro-duction for that herd. The expected annual enteric emissions reduction alone is equivalent to removing over 70 gas powered cars from the road for one year.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Self-efficacy, goal setting and intention for going to sleep
Creators: name: Westrik, Niels
name: Pruydt, Katrien
name: Mulders, Marieke
name: Custers, Angela
name: Gjalt-Jorn Peters
name: Rohen, Audrey
name: Gobbi, Paola
name: Mijlhoff, Alice
Publisher: name: OSF Registries
Year: 2018

description: Determinants of sleeping behaviour: self-efficacy, goal setting and intention
Too many? Not enough? Costs and opportunities associated with dairy replacement heifer inventory
Creators: name: Overton, Michael W.
name: Eicker, Steve
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: replacement rate
dairy replacement heifers
opportunity cost

description: Replacement rate (RR), also commonly called cull rate or herd turnover, is the proportion of the adult herd that enters the herd every year, and in a steady-state herd, the number of animals exiting equals the number of animals that enter; thus, the RR is determined by replacement availability. Failing to produce an adequate number of replacements will lower replacement cost but negatively impact profitability by delaying the replacement of inferior producers. The appropriate number of heifers to pro­duce varies by herd but is dependent upon the herd’s anticipated replacement needs plus any buffer allowance. Focusing on ge­netic composition and improvement of feeding and management strategies will yield higher quality heifers with higher predicted milk production that impact cow replacement decision making. A sufficient and steady flow of replacement heifers will enable dairies to replace problem cows or soon-to-be problem cows ear­lier, thus improving not only economic performance, but also animal welfare and market values..
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
MOESM8 of A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei
Creators: name: Lei, Chao
name: Wang, Jingzhi
name: Liu, Yuanyuan
name: Liu, Xinqiang
name: Zhao, Guoping
name: Wang, Jin
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 8: Figure S8. Effect of rifamycins to the transcription of rifP. Rifamycin SV and rifamycin B were added into the LYZL11 culture medium, respectively, and the rifP transcriptional level was measured at 24Â h after the addition of rifamycins. DMSO was used as a blank control and rpoB was used as an internal control.
Family utilization of early childhood education and care services in Beijing: family characteristics, employment effects,and parent satisfaction
Creators: name: Pan, Beibei
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Recent years have seen a marked increase in interest in early childhood education and care (ECEC) because of an enhanced recognition of the role of early intervention in the life cycle skill formation and the growth of knowledge based economies. However, formulation of Chinese ECEC policy has been hampered by a paucity of high quality empirical studies of ECEC provision and utilization. Aware of the significant role of empirical studiesin identifying the problemsand developing solutions for addressing ECEC policy and practice, this thesis examines family utilization of ECEC services in Beijing. More specifically, the study clarifieswho utilizes ECEC services in Beijing, how utilization relates to parents’ employment and whether parents are satisfied with the services received. Atotal of 416 questionnaires were gathered and 44 parents were interviewed in order to provide a comprehensive understanding of the consumption of ECEC services by relating service utilization to family characteristics, parent employment and satisfaction. Findings indicate that four factors (child age, migrant status, Guanxi, and family income) emerged to influence family utilization of ECEC services at a significant level.Families with children under three, migrant families, low-income families, and families without Guanxi were identified as being disadvantaged in relation to ECEC. Parent employment is found to have divergent impacts on ECEC utilization depending on work conditions (e.g. wage and working hours) and/or service arrangement (e.g. location and fees). The empirical investigation revealed that ECEC utilization can make it possible for parents to work both by providing them with labour time that they can sell in the market place and by enabling them to gain the income they need to pay for ECEC services.It is also shown parents are overwhelmingly satisfied with the services utilized by parents and that quality factors (e.g. class size, teacher qualification, facilities, etc.) rather than practical factors (e.g. price, timetable, location, etc.) are the primary determinant of parents’ satisfaction. It is hoped that the findings derived from this investigation will inform China’s effort to expand ECEC utilization nationwide in five aspects in relation to funding models, service distribution, quality regulations, information system, and data analysis.
title: 01_2299
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
The correlation between experiential attitude and self-efficacy in relation to going to sleep every night at the same time.
Creators: name: Rohen, Audrey
name: Gjalt-Jorn Peters
name: Mijlhoff, Alice
name: Pruydt, Katrien
name: Gobbi, Paola
name: Westrik, Niels
name: Custers, Angela
name: Mulders, Marieke
Publisher: name: OSF Registries
Year: 2018

description: The correlation between experiential attitude and self-efficacy in relation to going to sleep every night at the same time.
Structural insights into the recognition of CD1d-restricted self antigens by the natural killer T-cell T-cell antigen receptor
Creators: name: Clarke, Andrew James
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: This thesis investigates the molecular mechanisms of self-recognition by the Natural Killer T cell (NKT cell) T cell antigen Receptor (TCR). A number of crystal structures of complexes comprising an “autoreactive” NKT TCR bound to CD1d presenting a range of different host antigens have been elucidated in this work. With respect to the TCR used in these studies, the NKT TCR autoreactivity is driven by a hydrophobic region of the β-chain (the CDR3β loop) which comprises a “di-leucine motif”. This motif interacts with a hydrophobic patch of the CD1d α2 helix, and it appears that this interaction is the primary mechanism behind the autoreactivity of this NKT TCR. Accordingly, this data supports a general mechanism that the NKT TCRs develop "autoreactivity" by possessing CDR3β sequences that can interact CD1d directly over a particular threshold, in a ligand independent manner. Of course, the NKT TCRs are not completely ligand independent, and it is presented herein that some lipid antigens (e.g., GD3) will disrupt the ability, via steric hindrance, for the TCR to bind to dock onto CD1d. Further, this thesis discloses the mechanism with respect to how a special group of lipid antigens, which feature β-linked carbohydrate headgroups, are recognized. The “β-linked” headgroups of these antigens naturally protrude directly out from the CD1d antigen binding grove when not bound to the NKT TCR, and accordingly, it was unknown how this antigen conformation would allow for NKT TCR recognition. Through the elucidation of complex crystal structures, it is observed that upon TCR engagement the β-linked antigen headgroup is pushed down flat against the CD1d α2 helix, which allows sufficient space for the TCR to dock.
Feedlot telemedicine
Creators: name: Jim, G. Kee
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023

description: Feedlot Health Management Services by TELUS Agriculture and Consumer Goods was founded in 1983. The company’s cli­ent base as well as the scope, scale, and quality of services of­fered by FHMS has grown exponentially thanks to the early and ongoing adoption of technologies now collectively referred to telemedicine. The integration of remote diagnoses with near real-time individual health and production record keeping soft­ware allows veterinary consultants to provide ongoing surveil­lance and oversight in client operations.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
The statistical mechanics of spanning forests
Creators: name: Bedini, Andrea
Publisher: name: figshare
Year: 2017
Subjects: subject: 10506 Statistical Mechanics, Physical Combinatorics and Mathematical Aspects of Condensed Matter
subject: FOS: Mathematics
subject: 20602 Field Theory and String Theory
subject: FOS: Physical sciences

description: This work collects the results of my PhD research activity. The main part is the study of the spanning forest model in a mean field approximation by the use of a recently introduced fermionic representation. These results have been published in the following papers in collaboration with S. Caracciolo and A. Sportiello. • A. Bedini, S. Caracciolo, and A. Sportiello, Hyperforests on the complete hypergraph by Grassmann integral representation, Journal of Physics A: Mathematical and Theoretical 41, 205003 (2008). • A. Bedini, S. Caracciolo, and A. Sportiello, Phase transition in the spanning- hyperforest model on complete hypergraphs, Nuclear Physics B 822, 493 (2009). A second an more recent subject of research concerns the development of a new general algorithm for the exact computation of statistical mechanics partition function on arbitrary graphs. This work has been done in collaboration with J. L. Jacobsen and its publication is still in progress. • A. Bedini, J. L. Jacobsen, Fast solution of NP-hard problems on large random graphs, in progress.
A new angle on the bovine foot
Creators: name: Goldsmith, Timothy J.
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: structural unsoundness
foot and leg scores
EPD

description: Structural unsoundness of beef cattle is an important issue for producers and contributes to issues of lameness and injury that result in increased treatment, culling and death in the beef cow-calf segment. In recent years, utilization of structural scoring in the form of foot and leg phenotype scores as an evaluation tool for genetic evaluation to assess the structural conformation of beef cattle in many countries including the United States. The different breed organizations in the United States have devel­oped resources for breeders to assess and capture data related to foot and leg scores with utilization varying from within herd culling to expected progeny difference development and utiliza­tion within economic selection indexes. Awareness of structural scoring and associated resources by veterinarians as well as a baseline knowledge of utilization within genetic evaluations, management approaches and environmental risk factors that magnify structural unsoundness into lameness and injury events is an opportunity to provide valuable insight and direction to producers in the form of prevention and selection.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Bovine trichomoniasis overview and testing
Creators: name: Funnel, Bethany J.
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: trichomoniasis
Tritrichomonas fetus
infertility
abortion

description: Bovine trichomoniasis, caused by Tritrichomonas foetus, is a venereal disease of cattle, resulting in infertility, pregnancy losses, abortion and delayed calving seasons. The disease has global distribution, with greater prevalence in areas in which natural service is the primary means of reproduction. When ar­tificial insemination, with appropriate hygiene practices, is im­plemented, as well as aggressive testing and culling of positive bulls, control and eradication of the disease is possible. Addi­tionally, minimizing co-mingling of animals with unknown sta­tus through herd additions or on public grazing lands will help decrease the likelihood of introduction into negative herds, and contribute significantly to the decrease in prevalence in the local region. Testing methods have improved over the last 100 years; however, proper sample collection and handling are still paramount to gaining true positive results in infected bulls.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Benefits of using LVTs/assistants in food animal medicine
Creators: name: Aiton, Blake
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: technician
value added
efficiency

description:  


The use of veterinary technicians or veterinary assistants in food animal medicine, especially cow-calf medicine, is highly underutilized, and is an area that should be more thoroughly explored. Often, bovine veterinarians bring no help for chute side activities such as bangs vaccinating, pregnancy diagnosis, ultrasound, breeding soundness exams, and routine vaccina­tion of cattle. A very obvious benefit to bringing a technician to the field is increased efficiency of work, as most procedures at the chute are often where activities take place that ultimately decrease pace. That being said, many other benefits of bring­ing trained help often go unrecognized, such as quality of chute side activities, increased client/clinic relationship, and most importantly, value-added services. With the rise in lay people diagnosing pregnancies and conducting breeding soundness exams, adding perceived value is crucial in maintaining high-value services in your clinic, as well as separating ourselves from the lay person.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
MOESM9 of A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei
Creators: name: Lei, Chao
name: Wang, Jingzhi
name: Liu, Yuanyuan
name: Liu, Xinqiang
name: Zhao, Guoping
name: Wang, Jin
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Computational Biology

description: Additional file 9: Table S1. Strains and plasmids used in this study.
NAHMS 2021 Feedlot study
Creators: name: Fossler, Charles
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: NAHMS
feedlot
USDA
monitoring

description:  


 The National Animal Health Monitoring System (NAHMS) con­ducts national studies on the health and health management of U.S. domestic livestock populations. In the NAHMS Feedlot 2021 study, for feedlots that placed cattle not born and raised on the operation slightly over half of cattle placed (51.1%) came direct­ly from a cow-calf operation or a stocker or backgrounder oper­ation, while 41.2% came from a sale barn. Of the cattle placed in 2020, 85.1% were placed with the intention of meeting no specif­ic marketing claims, 0.5% of cattle were placed to meet certified organic claims, 8.4% were placed to meet no or limited antibi­otic use claims, and 10.2% were placed to meet no hormone use claims. About three-fourths (73.1%) of feedlots used antibiotics in any form in 2020. Of these feedlots: 22.4% gave injectable an­tibiotics to cattle as a group; 67.6% gave injectable antibiotics to sick cattle; 42.8% gave antibiotics in feed; and 4.5% gave antibi­otics in water. Most feedlots (85.1%) used a veterinarian in 2020. About two-thirds of feedlots (64.2%) felt that on January 1, 2017, they had all the resources necessary to manage the Veterinary Feed Directive (VFD) rule change.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Building resilience in the cow herd with a systems approach
Creators: name: Stokka, Gerald
name: Sawyer, Jason
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: resilience
AUE
system

description:  


Veterinarians involved with bovine practice are the main source of information to clients related to animal well-being. To remain relevant and bring value to clients, we must move from the pathogen/disease paradigm to one that encompasses systems thinking, particularly as it relates to building resil­ience in the system. Systems thinking is the ability to identify related forces that are a part of the business of cattle raising. Animal health can be measured with objective indices such as morbidity and mortality, and inputs spent on antibiotic use and preventive vaccines. When animal health issues occur in well-managed herds, resist the temptation to only search for pathogens related to disease; instead, ask the appropriate ques­tions and seek out information necessary to identify the system of the ranch and look for ways to return to balance. Aspects of the system that must be addressed include genetic selection pressure, nutrition, grazing systems and management, envi­ronment, handling facilities, people behavior, competing enter­prises, and labor resources. Trust with clients is critical to com­munication and to implement strategies to regain resilience and balance in the system.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings