cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
HealthData@EU Pilot - Deliverable 6.2 HealthDCAT-AP "Recommendations on further development and deployment for possible EU-wide uptake"
Creators: name: Health Data Hub
Publisher: name: Zenodo
Year: 2025

description: This document presents recommendations for the further development and potential EU-wide adoption of HealthDCAT-AP, an extension of the DCAT Application Profile for dataset catalogues in Europe. HealthDCAT-AP is specifically designed to describe health datasets and dataset access services, ensuring they are consistently represented and easily discoverable across various platforms.

The principal objective of the Health Data Catalog Application Profile (HealthDCAT-AP) is to establish a standardized, interoperable metadata schema tailored to the health domain. This schema is intended to facilitate the discovery, sharing, and reuse of health datasets across the European Union. By aligning with the broader DCAT-AP (Data Catalog Vocabulary Application Profile) standard, HealthDCAT-AP ensures that health-related datasets are uniformly described, promoting interoperability and enabling seamless data exchange among researchers, public health institutions, policymakers, and other stakeholders.

HealthDCAT-AP introduces specific extensions to the DCAT-AP model to meet the unique requirements of the health sector. This standardization is crucial for the European Health Data Space (EHDS) framework, enabling effective health data sharing across Europe. By enhancing the accessibility and availability of health data, HealthDCAT-AP plays an essential role in helping the EHDS achieve its objectives of improving public health outcomes, advancing research, and informing policy-making across the EU, all while upholding stringent data protection and privacy standards.

This document is the second and final deliverable of Work Package 6 of the HealthData@EU pilot project. The first deliverable, the draft specification of HealthDCAT-AP, is available at HealthDCAT-AP Draft Specification.

The development of HealthDCAT-AP will continue transparently and publicly within the framework of the Second Joint Action Towards the European Health Data Space (TEHDAS2).
Vida Stare, Kranj, nekropola iz časa preseljevanja ljudstev
Creators: name: Ament, Hermann
Publisher: name: Acta Praehistorica et Archaeologica
Year: 2019

description: Rezension zu: Vida Stare, Kranj, nekropola iz časa preseljevanja ljudstev (s prispevkoma Zdenko Vinski, Ovrednotenje grobnih pridatkov, in István Kiszely, Antropoliški pogledi). Katalogi in monografije - Catalogi et Monographiae 18. Narodni muzej v Ljubljani, Ljubljana 1980. 124 S., 21 Abb., 1 Farbtaf., 136 Taf.
description: Acta Praehistorica et Archaeologica, Bd. 11/12 1980/1981(1981)
Double ramification cycles on the moduli spaces of curves
Creators: name: Janda, F.
name: Pandharipande, R.
name: Pixton, A.
name: Zvonkine, D.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: Curves of genus g which admit a map to CP1 with specified ramification profile mu over 0 and nu over infinity define a double ramification cycle DR_g(mu,nu) on the moduli space of curves. The study of the restrictions of these cycles to the moduli of nonsingular curves is a classical topic. In 2003, Hain calculated the cycles for curves of compact type. We study here double ramification cycles on the moduli space of Deligne-Mumford stable curves.
 The cycle DR_g(mu,nu) for stable curves is defined via the virtual fundamental class of the moduli of stable maps to rubber. Our main result is the proof of an explicit formula for DR_g(mu,nu) in the tautological ring conjectured by Pixton in 2014. The formula expresses the double ramification cycle as a sum over stable graphs (corresponding to strata classes) with summand equal to a product over markings and edges. The result answers a question of Eliashberg from 2001 and specializes to Hain's formula in the compact type case.
 When mu and nu are both empty, the formula for double ramification cycles expresses the top Chern class lambda_g of the Hodge bundle of the moduli space of stable genus g curves as a push-forward of tautological classes supported on the divisor of nonseparating nodes. Applications to Hodge integral calculations are given.
description: Appendix on Polynomiality by A. Pixton
MicroRNA-409-3p regulates macrophage migration in polymyositis through targeting CXCR4
Creators: name: Ye, Qin
name: Chen, Zhaoying
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: Macrophage migration and infiltration contribute to the pathogenesis of polymyositis (PM). This study aims to investigate the effect and underlying mechanism of miR-409-3p on macrophage migration in PM. The GSE143845 database was used to predict the altered expression of microRNAs (miRNAs) in PM. The quantitative real-time PCR (qRT-PCR), western blot and Transwell assay were performed to detect migration of macrophages and expressions of related molecules. A luciferase activity assay was conducted to confirm the binding of miR-409-3p and CXCR4 3'-UTR. Next, a mouse model of experimental autoimmune myositis (EAM) was established. Haematoxylin and eosin (HE) staining, immunohistochemistry (IHC), and enzyme-linked immunosorbent assay (ELISA) were used to measure associated factors. MiR-409-3p was downregulated in PM of GSE143845 database and patients. Differently, the serum creatine kinase (s-CK), TNF-α, and IL-6 in patients with PM were increased. Furthermore, miR-409-3p mimic transfection reduced the migration of macrophages and CXCR4 levels, while miR-409-3p inhibitor exerted the opposite effects. CXCR4 was a target of miR-409-3p, and the effect of CXCR4 on promoting macrophage migration was reversed by miR-409-3p mimic. In vivo, miR-409-3p agomir injection reduced inflammatory cells, macrophages, and TNFα and IL-6 levels in muscles and serum of EAM mouse models. In conclusion, miR-409-3p reduces the migration of macrophages through negatively regulating CXCR4 expression in PM.
Elevated miR-34a expression and altered transcriptional profile are associated with adverse electromechanical remodeling in the heart of male rats exposed to social stress
Creators: name: Andolina, Diego
name: Savi, Monia
name: Ielpo, Donald
name: Barbetti, Margherita
name: Bocchi, Leonardo
name: Stilli, Donatella
name: Ventura, Rossella
name: Iacono, Luisa Lo
name: Sgoifo, Andrea
name: Carnevali, Luca
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: This study investigated epigenetic risk factors that may contribute to stress-related cardiac disease in a rodent model. Experiment 1 was designed to evaluate the expression of microRNA-34a (miR-34a), a known modulator of both stress responses and cardiac pathophysiology, in the heart of male adult rats exposed to a single or repeated episodes of social defeat stress. Moreover, RNA sequencing was conducted to identify transcriptomic profile changes in the heart of repeatedly stressed rats. Experiment 2 was designed to assess cardiac electromechanical changes induced by repeated social defeat stress that may predispose rats to cardiac dysfunction. Results indicated a larger cardiac miR-34a expression after repeated social defeat stress compared to a control condition. This molecular modification was associated with increased vulnerability to pharmacologically induced arrhythmias and signs of systolic left ventricular dysfunction. Gene expression analysis identified clusters of differentially expressed genes in the heart of repeatedly stressed rats that are mainly associated with morphological and functional properties of the mitochondria and may be directly regulated by miR-34a. These results suggest the presence of an association between miR-34a overexpression and signs of adverse electromechanical remodeling in the heart of rats exposed to repeated social defeat stress, and point to compromised mitochondria efficiency as a potential mediator of this link. This rat model may provide a useful tool for investigating the causal relationship between miR-34a expression, mitochondrial (dys)function, and cardiac alterations under stressful conditions, which could have important implications in the context of stress-related cardiac disease.
Multimodality Treatment by FOLFOX plus HIFU in a Case of Advanced Pancreatic Carcinoma. A Case Report
Creators: name: Dimitrov, Dobromir
name: Andreev, Tihomir
name: Feradova, Hyuliya
name: Ignatov, Borislav
name: Zhou, Kunn
name: Johnson, Colin
name: Delijski, Tashko
name: Gortchev, Grigor
name: Tomov, Slavcho
Publisher: name: JOP. Journal of the Pancreas
Year: 2015
Subjects: High-Intensity Focused Ultrasound Ablation; Pancreas; Pancreatic Neoplasms; Quality of Life

description: Context Pancreatic cancer is one of the most aggressive malignant diseases in which the survival rate has not improved in the past 40 years. Case report A fifty-one-year-old male patient with inoperable metastatic pancreatic cancer and low response to chemotherapy with gemcitabine as single therapy underwent palliative high intensity focused ultrasound (HIFU) ablation. Continuing chemotherapy with folinic acid, oxaliplatin and 5-fluorouracil (FOLFOX) was made. Tools, provided by the European Organization for Research and Treatment of Cancer (EORTC) were used to evaluate his quality of life. The Global Health Status improved from 25 to 42 out of 100 and the body mass index (BMI) increased from 14.9 to 18.1 kg/m2. Measured by the visual analog scale, the pain was reduced from 7 to 2 out of 10. Twelve months after the HIFU ablation, CT revealed decreased size of the tumor and liver lesions. Conclusion FOLFOX plus interventional, physical destruction of the primary tumor by HIFU sufficiently improved the quality of life, reduced pancreatic pain and provided better survival in this case.

Image: Hyper-echogenic tumor immediately after HIFU ablation.
description: JOP. Journal of the Pancreas, Vol 16, No 1 (2015): January - p. 1-98
Early-Phase Thin-Slice CT in the Diagnosis of Small Insulinomas
Creators: name: Ishioka, Hideki
name: Sata, Naohiro
name: Ishiguro, Yasunao
name: Lefor, Alan
name: Yasuda, Yoshikazu
Publisher: name: JOP. Journal of the Pancreas
Year: 2015
Subjects: Insulinoma; Pancreas; Pancreatic Polypeptide

description: Context Insulinomas, which are generally smaller than 2 cm, may be difficult to detect by routine imaging modalities including abdominal ultrasonography, computed tomography, and magnetic resonance imaging. Although preoperative detection of insulinomas is essential for operative planning, it is often challenging due to their small size. While arterial stimulation and venous sampling has been used in patients with insulinomas it has been largely supplanted by early-phase thin-slice computed tomography. Case report We report three patients with insulinomas, which were not detected by routine computed tomography scan, but were successfully imaged using early-phase thin-slice computed tomography. Enucleation was performed in all patients based on preoperative imaging. All three patients had an unremarkable postoperative course. Conclusion Early-phase thin-slice computed tomography is recommended for the preoperative identification of insulinomas. This non-invasive imaging technique should be considered before performing arterial stimulation and venous sampling.

Image. CT scan before and 35, 55, and 80 seconds after the administration of contrast agent.
description: JOP. Journal of the Pancreas, Vol 16, No 1 (2015): January - p. 1-98
Higher-genus quasimap wall-crossing via localization
Creators: name: Clader, Emily
name: Janda, Felix
name: Ruan, Yongbin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Algebraic Geometry (math.AG)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 14N35

description: We give a new proof of Ciocan-Fontanine and Kim's wall-crossing formula relating the virtual classes of the moduli spaces of $ε$-stable quasimaps for different $ε$ in any genus, whenever the target is a complete intersection in projective space and there is at least one marked point. Our techniques involve a twisted graph space, which we expect to generalize to yield wall-crossing formulas for general gauged linear sigma models.
description: 26 pages, v2 agrees with published version
Venlafaxine reduces the striatal il6/il10 ratio and increases hippocampal GR expression in female mice subjected to chronic social instability stress
Creators: name: Labaka, Ainitze
name: Gómez-Lazaro, Eneritz
name: Goñi-Balentziaga, Olatz
name: Pérez-Tejada, Joana
name: Vegas, Oscar
name: Garmendia, Larraitz
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Women are twice as likely as men to develop depression and antidepressant treatment is more frequent in females. Moreover, neuroinflammatory changes related to affective disorders differ in accordance with sex. Despite this evidence, female populations have been largely omitted from preclinical experiments studying antidepressants. The aim of this work is to analyze the potential restorative effect of venlafaxine on an animal model of depression. Female CD1 mice were subjected to chronic social instability (CSI) stress for 7 weeks, and were administered venlafaxine during the last 3 weeks of the stress period. Behavioral and physiological parameters were then analyzed. Stressed mice showed a decreased sucrose preference and increased whisking behavior, and had a lower body weight, higher plasma corticosterone levels and increased hypothalamic GR expression. They also had lower levels of 5-HT, 5-HIAA and NA and a higher KYN/TRYP ratio in the hippocampus. Moreover, CSI increased striatal IL-6 mRNA expression levels. Venlafaxine treatment reduced the striatal IL-6/IL-10 ratio and increased hippocampal GR expression, although it did not reverse stress-induced behavioral changes. In conclusion, seven weeks of exposure to CSI produced depressive-like alterations in female mice. The venlafaxine treatment regimen was found to have a modest anti-inflammatory effect in the striatum and increased hippocampal GR mRNA, although it failed to redress stress-induced behavioral disturbances.
Surgical Intervention for Mediastinal Pancreatic Pseudocysts. A Case Series and Review of the Literature
Creators: name: Metaxa, Dafni
name: Balakrishnan, Anita
name: Upponi, Sara
name: Huguet, Emmanuel L
name: Praseedom, Raaj K
Publisher: name: JOP. Journal of the Pancreas
Year: 2015
Subjects: Mediastinum; Pancreas; Pancreatic Pseudocyst

description: Context Development of mediastinal pancreatic pseudocysts is a rare complication of pancreatitis. There is currently no consensus on the optimal management of this condition, options for which include conservative management with somatostatin analogues, endoscopic drainage procedures and surgery. Case report Here we present two patients with mediastinal pancreatic pseudocysts which were initially managed endoscopically. However, in both cases, this led to complications secondary to the endoscopic procedures, recurrence or non-resolution of symptoms, requiring surgical cystogastrostomy and/or cystojejunostomy. Conclusion These cases suggest that surgery may be ultimately necessary for mediastinal pancreatic pseudocysts where endoscopic procedures might have a high likelihood of failure.

Image: A well-defined rim enhancing pseudocyst.
description: JOP. Journal of the Pancreas, Vol 16, No 1 (2015): January - p. 1-98
Mound 2 at Sutton Hoo
Creators: name: Lee, Stuart
Publisher: name: University of Oxford
Year: 2022
Subjects: Archaeology

description: Mound 2 was excavated by Basil Brown in 1938, the year before his famous discovery of the ship burial in Mound 1. It was re-investigated in the 1980s and 90s by Martin Carver, who concluded it was originally a rich chamber burial covered by a boat and then buried in the mound. Carver's team reconstructed the mound to something like its original height and profile, the only mound in the royal graveyard for which this has been done.
Security Camera Movie and ERP Data Matching System to Prevent Theft
Creators: name: Yamato, Yoji
name: Fukumoto, Yoshifumi
name: Kumazaki, Hiroki
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: "(c) 2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works." In this paper, we propose a SaaS service which prevents shoplifting using image analysis and ERP. In Japan, total damage of shoplifting reaches 450 billion yen. Based on cloud and data analysis technology, we propose a shoplifting prevention service with image analysis of security camera and ERP data check for small shops. We evaluated movie analysis. Y. Yamato, Y. Fukumoto and H. Kumazaki, "Security Camera Movie and ERP Data Matching System to Prevent Theft," IEEE Consumer Communications and Networking Conference (CCNC 2017), pp.1021-1022, DOI: 10.1109/CCNC.2017.7983275, Jan. 2017.
description: 2 pages, 2 figures, IEEE Consumer Communications and Networking Conference (CCNC2017), pp.1021-1022, Jan. 2017
Narrow Valley Leading to the Royal Graveyard at Sutton Hoo
Creators: name: Team, Woruldhord Project
Publisher: name: University of Oxford
Year: 2022
Subjects: Archaeology

description: A view from the narrow valley up which the ship in the great Sutton Hoo ship burial would have been dragged, looking towards the ridge behind lay the plateau on which the graveyard is located. The house belonged to Mrs Pretty, the landowner at the time of the ship burial's discovery in 1939. It is now owned by English Heritage.
Wandering Spleen with Torsion Causing Pancreatic Volvulus and Associated Intrathoracic Gastric Volvulus: An Unusual Triad and Cause of Acute Abdominal Pain
Creators: name: Aswani, Yashant
name: Anandpara, Karan Manoj
name: Hira, Priya
Publisher: name: JOP. Journal of the Pancreas
Year: 2015
Subjects: Abdomen, Acute; Gastric Volvulus, Intrathoracic; Pancreas; Wandering Spleen

description: Context Wandering spleen is a rare medical entity in which the spleen is orphaned of its usual peritoneal attachments and thus assumes an ever wandering and hypermobile state. This laxity of attachments may even cause torsion of the splenic pedicle. Both gastric volvulus and wandering spleen share a common embryology owing to maldevelopment of the dorsal mesentery. Gastric volvulus complicating a wandering spleen is, however, an extremely unusual association, with a few cases described in literature. Case report We present a case of a young female who presented with acute abdominal pain and vomiting. Radiological imaging revealed a intrathoracic gastric volvulus, torsion in an ectopic spleen, and additionally demonstrated a pancreatic volvulus - an unusual triad, reported only once, causing an acute abdomen. Conclusion The patient subsequently underwent an emergency surgical laparotomy with splenopexy and gastropexy.

Image: Grossly distended stomach with Ryle’s tube in situ.
description: JOP. Journal of the Pancreas, Vol 16, No 1 (2015): January - p. 1-98
Inhalt
Creators: name: Redaktion, Die
Publisher: name: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Year: 2019

description: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege, Bd. 16 Nr. 12 (1963): Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Narrow Valley Leading to the Royal Graveyard at Sutton Hoo
Creators: name: Lee, Stuart
Publisher: name: University of Oxford
Year: 2022
Subjects: Archaeology

description: A view from the narrow valley up which the ship in the great Sutton Hoo ship burial would have been dragged, looking towards the ridge behind lay the plateau on which the graveyard is located. The house belonged to Mrs Pretty, the landowner at the time of the ship burial's discovery in 1939. It is now owned by English Heritage.
Somatostatinoma of the Minor Papilla Treated by Local Excision in a Patient with Neurofibromatosis Type 1
Creators: name: Bhandari, Ramesh
name: Riddiough, Georgina
name: Lokan, Julie
name: Weinberg, Laurence
name: Efthymiou, Marios
name: Nikfarjam, Mehrdad
Publisher: name: JOP. Journal of the Pancreas
Year: 2015
Subjects: Mastectomy, Segmental; Neuroendocrine Tumors; Neurofibromatoses; Pancreatic Ducts

description: Context Somatostatinoma arising from the minor papilla in a patient with neurofibromatosis type 1 (NF1) is a known but very rare condition, which may cause non-specific symptoms and can present because of its mass effect. Case report A fifty-year-old female presenting with ongoing non-specific abdominal pain for a few months duration was found to have a mass involving the minor papilla. She had a history of NF1 but was otherwise well. Magnetic resonance imaging showed a dilated pancreatic duct and the finding of pancreatic divisum. The lesion was 18fluorine-fluoro-2-deoxyglucose positron emission tomography/computed tomography and 68gallium (Ga) DOTATATE negative. Endoscopic ultrasound revealed a 1.7 cm lesion confined to the minor ampulla. Endoscopic retrograde pancreatography attempts with biopsy and endoscopic ultrasound fine needle aspiration biopsy were inconclusive and resulted in mild pancreatitis on two occasions. Open local excision of the minor papilla was undertaken without complications. Histology confirmed a completely excised grade 1 neuroendocrine tumor with intense diffuse somatostatin staining. Conclusion Somatostatinoma of the minor papilla is a rare tumor that most commonly occurs in the setting of NF1 and may be amenable to local excision.

Image: Pancreatic duct reconstruction.
description: JOP. Journal of the Pancreas, Vol 16, No 1 (2015): January - p. 1-98
Absolute continuity of non-homogeneous self-similar measures
Creators: name: Saglietti, Santiago
name: Shmerkin, Pablo
name: Solomyak, Boris
Publisher: name: arXiv
Year: 2017
Subjects: subject: Dynamical Systems (math.DS)
subject: Classical Analysis and ODEs (math.CA)
subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 28A78, 28A80 (Primary) 37A45, 42A38 (secondary)

description: We prove that self-similar measures on the real line are absolutely continuous for almost all parameters in the super-critical region, in particular confirming a conjecture of S-M. Ngai and Y. Wang. While recently there has been much progress in understanding absolute continuity for homogeneous self-similar measures, this is the first improvement over the classical transversality method in the general (non-homogeneous) case. In the course of the proof, we establish new results on the dimension and Fourier decay of a class of random self-similar measures.
description: v3: the statement of Theorem 1.3 was changed (the selection measure for the "model" of a random self-similar measure is assumed to be Bernoulli rather than an arbitrary ergodic shift-invariant measure; this was implicitly used in the proof. The original formulation is still correct; see the footnote on p.8 for details). The main result: Theorem 1.1 is unchanged
Ausstellungskataloge und Museumsberichte
Creators: name: Redaktion, Die
Publisher: name: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Year: 2019

description: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege, Bd. 16 Nr. 2 (1963): Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Archäologische Kommission für Niedersachsen e.V.
Creators: name: Bärenfänger, Rolf
Publisher: name: Nachrichten aus Niedersachsens Urgeschichte
Year: 2019

description: Nachrichten aus Niedersachsens Urgeschichte, Bd. 78 (2009): Nachrichten aus Niedersachsens Urgeschichte
Arterial Pseudoaneurysms Following Hepato-Pancreato-Biliary Surgery: A Single Center Experience
Creators: name: Ielpo, Benedetto
name: Caruso, Riccardo
name: Prestera, Antonio
name: De Luca, Giuseppe Massimiano
name: Duran, Hipolito
name: Diaz, Eduardo
name: Fabra, Isabel
name: Olivares, Sergio
name: Quijano, Yolanda
name: Vicente, Emilio
Publisher: name: JOP. Journal of the Pancreas
Year: 2015
Subjects: Carotid Artery Injuries; Pancreatectomy; Uterine Artery Embolization

description: Context Arterial pseudoaneurysm is an uncommon lethal complication following hepato-pancreato-biliary surgery. Objective Aim of this study is to present and discuss the experience of a high volume oncological center. Methods Since 2007 all major surgeries performed at Sanchinarro Oncological Center have been included in a prospective database looking for postoperative arterial pseudonaurysm. Results Until June 2014, among 559 hepato-pancreato-biliary procedures, a total of 14 arterial pseudoaneurysms have been identified (2.5%). Sentinel bleeding was in 57% of cases. Failed arterial embolization occurred in 2 cases. Overall mortality rate was 28.5%. We also identified 3 asymptomatic pseudoaneurysms, one of them managed without embolization, developing a sudden bleeding and died after surgery. Conclusions According to our experience, pseudoaneurysm incidence is higher than reported in current literature and it can be successfully managed through arterial embolization. Furthermore, we found 3 asymptomatic pseudoaneurysms, whose management is still controversial.

Image: Bleeding pseudoaneurysm at CT with arterial phase.
description: JOP. Journal of the Pancreas, Vol 16, No 1 (2015): January - p. 1-98
Pancreaticopleural Fistula: A Review
Creators: name: Aswani, Yashant
name: Hira, Priya
Publisher: name: JOP. Journal of the Pancreas
Year: 2015
Subjects: Cholangiopancreatography, Endoscopic Retrograde; Cholangiopancreatography, Magnetic Resonance; Pancreatitis, Chronic; Pleural Effusion; Pancreatic Fistula

description: Pancreaticopleural fistula is a rare complication of chronic pancreatitis consequent to posterior disruption of the pancreatic duct. The fistulous track ascends into the pleural cavity and gives rise to large volumes of pleural fluid. Pancreaticopleural fistula thus poses a diagnostic problem since the source of pleural fluid is extrathoracic. To further complicate the matter, abdominal pain is seldom the presenting or significant feature. The pleural effusion is typically rapidly accumulating, recurrent and exudative in nature. Pleural fluid amylase in the correct clinical setting virtually clinches the diagnosis. Magnetic resonance cholangiopancreatography, endoscopic retrograde cholangiopancreatography and computed tomography may delineate the fistula and thus aid in diagnosis. Endoscopic retrograde cholangiopancreatography has emerged both as a diagnostic as well as therapeutic modality in select patients of pancreaticopleural fistula while magnetic resonance cholangiopancreatography is the radiological investigation of choice. Besides delineating the ductal anatomy, magnetic resonance cholangiopancreatography can help stratify patients for appropriate management. A near normal or mildly dilated pancreatic duct responds well to chest drainage with octreotide while endoscopic stent placement benefits patients with duct disruption located in head or body of pancreas. Failure of medical or endoscopic therapy calls in for surgical intervention. Besides, a primary surgical management may be tried in patients with complete ductal obstruction, ductal disruption in tail or ductal obstruction proximal to fistula site.

Image: Logo of Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital. Mumbai, Maharashtra, India.
description: JOP. Journal of the Pancreas, Vol 16, No 1 (2015): January - p. 1-98
St Martin's Church, Canterbury
Creators: name: Team, Woruldhord Project
Publisher: name: University of Oxford
Year: 2022
Subjects: Archaeology

description: St Martin's is the original building given to St Augustine by King Aethelberht when he arrived in 597, when it was one of the few Roman buildings still standing. It is thus perhaps the oldest church building in continuous use in England. The chancel is the oldest part of the building, seen here from its south side, showing the Roman brickwork and two low blocked-up doorways, one arched and one square.
A Critique on the Article Describing "Pancreatic Mucinous Cystic Neoplasm Size Using CT Volumetry, Spherical and Ellipsoid Formulas: Validation Study"
Creators: name: Aswani, Yashant
name: Anandpara, Karan Manoj
name: Acharya, Shrikala
Publisher: name: JOP. Journal of the Pancreas
Year: 2015
Subjects: Pancreatic Cyst; Tomography, X-Ray Computed; Data Interpretation, Statistical

description: No abstract available.

Image: Seth Gordhandas Sunderdas (GS) Medical College and King Edward Memorial (KEM) Hospital. Mumbai, Maharashtra, India
description: JOP. Journal of the Pancreas, Vol 16, No 1 (2015): January - p. 1-98
THE ROLE OF THE B CELL ANTIGEN RECEPTOR IN A MOUSE MODEL OF NON-HODGKIN LYMPHOMA
Creators: name: VARANO, GABRIELE
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: The B cell antigen receptor (BCR) plays a central role both in early B-cell development and in mature B cells, where it controls survival and allows the organism to mount protective immune responses against foreign antigens. Surface BCR expression is retained in most types of Non-Hodgkin B-cell lymphomas (NHL), where it has been proposed to participate to tumor initiation, maintenance and progression. This study has provided for the first time an in vivo genetic proof for the role of the BCR in B-cell lymphomagenesis.
Using the ?-MYC Burkitt lymphoma (BL) mouse model, in which conditional ablation of the BCR can be induced in c-MYC transformed B cells through the Cre/loxP recombination system, I provide evidence for the essential role of the BCR in tumor maintenance. Acute BCR ablation in ?-MYC lymphomas delayed cell cycle progression and augmented apoptosis, causing the rapid disappearance of BCR- tumor cells when these cells were grown both in vitro and in vivo in competition with their BCR+ counterparts. Similar results were obtained using the human Burkitt lymphoma cell line, RAMOS.
This study has also elucidated crucial effectors of tonic BCR signalling that influence the survival and growth of BL cells. BCR inactivation led to a reduction in GSK3? phosphorylation, leading to an increase in its enzymatic activity. Importantly, treatment of lymphoma cells with a GSK3? small molecule inhibitor restored the ability of BCR-deficient lymphomas to compete with their BCR+ counterparts. I could also show that c-MYC transformed B cells acquired exquisite sensitivity to the mTOR inhibitor rapamycin upon BCR inactivation.
Using a combination of quantitative proteome and whole transcriptome analyses we have started to shed light on the contribution of the BCR to the maintenance of c-MYC transformed B cells. In ?-MYC lymphomas, the BCR regulated a substantial number of MYC targets genes. Notably, the majority of these shared targets were normalized in BCR- tumor cells upon pharmacological inhibition of GSK3?. These result point to the tempting hypothesis that the BCR supports MYC-driven lymphomagenesis, by the inhibition of GSK3?-mediated phosphorylation and hence degradation of c-MYC protein.
Finally, our study demonstrates that the failure of c-MYC transformed B cells to grow in vivo is strictly dependent on the concomitant presence of their BCR+ counterparts. This result has important implications for the design of clinical trials limited to the use of inhibitors of the BCR signalling pathway for the treatment of BL and other forms of aggressive NHL. To avoid the outgrowth of BCR- escape variants in response to such treatments, we propose the integration in the therapeutic protocol of the mTOR inhibitor rapamacyin that showed high efficacy in the killing Ig receptor-less lymphoma cells.
Colonial Built Remains in Douala (Cameroon): Approaches to the Enhancement of Dissonant Heritage
Creators: name: OUSMANOU, ZOURMBA
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: Douala is a Cameroonian city located on the banks of the Wouri River, that experienced various economic, social, and spatial evolution due to the succession of colonial systems: German protectorate from 1884 to 1916, Franco-British condominium from 1916 to 1919, Mandate then Trusteeship regimes under the French supervision from 1919 to 1960. These Successive colonial systems have reshaped the urban space of Douala, through numerous projects and town planning initiatives. Some of these urban projects have been designed on the basis of massive expropriation of local populations, as well as urban segregation, for reasons of so-called hygiene. Urban construction and architectural forms in colonial Douala were conceived to impose Western hegemony. True support of power, colonial architecture in Douala reflects antagonistic urban initiatives, opposing the locals to the German and then French administration. Some of these buildings bear memories of forced labour, assassinations, racism, the imposition of cultural values, whips, and other inhuman and humiliating treatment that colonial administrators inflicted on local populations. On the other hand, within the former colonial powers in the postcolonial context, the imperial past in Cameroon is often equated with a glorious past of empire, which arouses nostalgia contrary to the difficult and painful tendencies of colonial memories in Africa. It is in this logic that the colonial past is subjected to selective oblivion, and idealisation aiming at its polishing. In this regard, the colonial buildings in Douala are the object of memory tensions that complexify their enhancement.
Colonial memory discrepancies can be explained by the dissonant heritage approach, theorised to highlight the tensions likely to affect the enhancement of historic sites in relation to atrocities. These are the sites of painful memories, with which various interest groups recognise linkages. The paradigm of Dissonant Heritage that emerged in the 1990s, inspired various other concepts in the study of heritage and heritage tourism, among which Difficult Heritage and Rejected Heritage. These evolving concepts recall the different possibilities to inspire from the Dissonant heritage, with a view to enhancing historical sites. In this logic, heritagisation models have emerged and inspired a specific heritage model applied to colonial built remains.
St Martin's Church, Canterbury
Creators: name: Lee, Stuart
Publisher: name: University of Oxford
Year: 2022
Subjects: Archaeology

description: St Martin's is the original building given to St Augustine by King Aethelberht when he arrived in 597, when it was one of the few Roman buildings still standing. It is thus perhaps the oldest church building in continuous use in England. The chancel is the oldest part of the building, seen here from its south side, showing the Roman brickwork and two low blocked-up doorways, one arched and one square.
Single-use MIMO system, Painlevé transcendents and double scaling
Creators: name: Chen, Hongmei
name: Chen, Min
name: Blower, Gordon
name: Chen, Yang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 34M55

description: In this paper we study a particular Painlevé V (denoted ${\rm P_{V}}$) that arises from Multi-Input-Multi-Output (MIMO) wireless communication systems. Such a $P_V$ appears through its intimate relation with the Hankel determinant that describes the moment generating function (MGF) of the Shannon capacity. This originates through the multiplication of the Laguerre weight or the Gamma density $x^α {\rm e}^{-x},\;x> 0,$ for $α>-1$ by $(1+x/t)^λ$ with $t>0$ a scaling parameter. Here the $λ$ parameter "generates" the Shannon capacity, see Yang Chen and Matthew McKay, IEEE Trans. IT, 58 (2012) 4594--4634. It was found that the MGF has an integral representation as a functional of $y(t)$ and $y'(t)$, where $y(t)$ satisfies the "classical form" of $P_V$. In this paper, we consider the situation where $n,$ the number of transmit antennas, (or the size of the random matrix), tends to infinity, and the signal-to-noise ratio (SNR) $P$ tends to infinity, such that $s={4n^{2}}/{P}$ is finite. Under such double scaling the MGF, effectively an infinite determinant, has an integral representation in terms of a "lesser" $P_{III}$. We also consider the situations where $α=k+1/2,\;\;k\in \mathbb{N},$ and $α\in\{0,1,2,\dots\}$ $λ\in\{1,2,\dots\},$ linking the relevant quantity to a solution of the two dimensional sine-Gordon equation in radial coordinates and a certain discrete Painlevé-II.
From the large $n$ asymptotic of the orthogonal polynomials, that appears naturally, we obtain the double scaled MGF for small and large $s$, together with the constant term in the large $s$ expansion. With the aid of these, we derive a number of cumulants and find that the capacity distribution function is non-Gaussian.
description: 30 pages
Postoperative Pancreatic Fistula: A Surgeon’s Nightmare! An Insight with a Detailed Literature Review
Creators: name: Seetharam, Prasad
name: Rodrigues, Gabriel Sunil
Publisher: name: JOP. Journal of the Pancreas
Year: 2015
Subjects: complications; Fistula; Pancreatectomy; Pancreaticoduodenectomy; Postoperative Period

description: Context Postoperative fistula formation is an important complication following pancreatic resections. Objective A large volume of literature without uniform conclusions is available regarding various controversies about postoperative pancreatic fistulae. The term postoperative pancreatic fistula includes fistula resulting from any surgery involving pancreas, most commonly pancreaticoduodenectomy and distal pancreatectomy. In this review, we have tried to present a comprehensive account of postoperative pancreatic fistula with particular emphasis on important controversies clouding the subject. Methods We performed MEDLINE literature search for relevant articles using the key words pancreas, pancreatic cancer, pancreatectomy, pancreatoduodenectomy, Whipple’s operation, postoperative, complications, fistula, management and treatment in various combinations with the Boolean operators AND, OR and NOT. Conclusions Postoperative pancreatic fistula is a troublesome complication of pancreaticoduodenectomy. Although the risk factors for postoperative pancreatic fistula have been extensively described, none of the methods recommended for preventing postoperative pancreatic fistula have been conclusively proved to be effective. While endoscopic treatment and percutaneous treatment form important aspects of treatment of postoperative pancreatic fistula, surgery may be required for select cases.

Image: Management of postoperative pancreatic fistula.
description: JOP. Journal of the Pancreas, Vol 16, No 2 (2015): March - p. 99-217
MESENCHYMAL STEM CELLS FROM HUMAN ADIPOSE TISSUE:CHARACTERIZATION AND IMMUNOMODULATORY PROPERTIES OF TISSUE AND CELLULAR PRODUCT
Creators: name: MESSAGGIO, FANUEL
Publisher: name: Universit� degli Studi di Milano
Year: 2014

description: Human adipose tissue ? derived stem cells (hADSCs) are routinely isolated from the stromal vascular fraction of homogenized adipose tissue.
In this study a mechanical, non-enzymatic method to obtain mesenchymal stem cells from the human subcutaneous adipose tissue, by use of the Lipogems� device has been set.
This instrument allows three micro-fragmentation steps of the lipoaspirate adipose tissue, in order to increase the stem cells bioavailability, residents in the stromal vascular fraction of the tissue, diminishing oil and blood residues.
The structural composition of the Lipogems� product is comparable to the original lipoaspirate adipose tissue, but differently, this mechanical procedure activates the expression of antigens such as ?-tubulin III.
The Lipogems� product could be processed to obtain hADSCs with different approaches, including the classical enzymatic treatment, a single centrifugation or a directly tissue culture, although the yield is different and it is associated to the used method. Freshly isolated they display surface markers that differ from those of cultured hADSCs.
The hADSCs derived from Lipogems� product have been systematically characterized for growth features, phenotype and multipotent differentiation potential. They fulfill the definition of mesenchymal stem cells provided by the International Society of Cell Theraphy (ISCT).
Notably, in basal growth condition Lipogems�- derived stem cells express at high percentages typical neural markers, such as GFAP, O4 and ?-tubulin III. The EPO Receptor (EPOR) is express when these cells grown in SCM medium. All these findings provide evidence that micro-fragmentation of lipoaspirate adipose tissue change some molecular features in the tissue resident cells so that hADSCs obtained in this condition become more plastic and adaptive to the extracellular signals.
The immunomodulatory properties of Lipogems�- derived stem cells have been evaluated by means of anti CD3 assay of co-culture with CD3+ T lymphocytes. They show a strongly suppressive effect on the T cells proliferation, maintaining a consistent T regulatory population.
Die Wirksamkeit von Tarifverträgen zur Steuerung des Marktverhaltens von Unternehmen
Creators: name: Grethe, Franziska
Publisher: name: Studentische Zeitschrift für Rechtswissenschaft Heidelberg – Wissenschaft Online
Year: 2019

description: Der nachfolgende Beitrag setzt sich mit der Frage auseinander, inwiefern der Abschluss von (Haus-)Tarifverträgen, die auf das Marktverhalten eines Unternehmens zuzugreifen versuchen, möglich ist. Dabei stehen sich die Berufsfreiheit des Unternehmers und die Koalitionsfreiheit der Tarifparteien diametral entgegen. Grundsätzlich denkbar sind nach der hier vertretenen Auffassung jedenfalls schuldrechtliche Tarifverträge und außertarifvertragliche Vereinbarungen. Jene verstoßen jedoch regelmäßig gegen Art. 12 Abs. 1 GG als verfassungsrechtliche Grenze, sodass Arbeitskämpfe zur Durchsetzung der tariflichen Regelungen unzulässig sind. Im Gegensatz dazu sind freiwillig geschlossene Tarifverträge vielmehr Ausdruck der Berufsfreiheit des Arbeitgebers und somit zulässig.
description: Studentische Zeitschrift für Rechtswissenschaft Heidelberg – Wissenschaft Online, Nr. 1 (2016): StudZR-WissOn
Center of mass distribution of the Jacobi unitary ensembles: Painleve V, asymptotic expansions
Creators: name: Zhan, Longjun
name: Blower, Gordon
name: Chen, Yang
name: Zhu, Mengkun
Publisher: name: arXiv
Year: 2018
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 34M55, 33C45

description: In this paper, we study the probability density function, $\mathbb{P}(c,α,β, n)\,dc$, of the center of mass of the finite $n$ Jacobi unitary ensembles with parameters $α\,>-1$ and $β>-1$; that is the probability that ${\rm tr}M_n\in(c, c+dc),$ where $M_n$ are $n\times n$ matrices drawn from the unitary Jacobi ensembles. We first compute the exponential moment generating function of the linear statistics $\sum_{j=1}^{n}\,f(x_j):=\sum_{j=1}^{n}x_j,$ denoted by $\mathcal{M}_f(λ,α,β,n)$.
title: Die Ausbildung von Amtswechsel und Amtsfristen als Problem zwischen Machtbesitz und Machtgebrauch in der Mittleren Republik (342 bis 217 v. Chr.)
Creators: name: Rilinger, Rolf
Publisher: name: Deutsches Archäologisches Institut
Year: 1970

description: Chiron, Bd. 8 (1978)
Buchrezension: Werle/Jessberger – Völkerstrafrecht
Creators: name: Schmid, Florian
Publisher: name: Studentische Zeitschrift für Rechtswissenschaft Heidelberg – Wissenschaft Online
Year: 2019

description: Rezension des Werkes „Völkerstrafrecht“ von Gerhard Werle und Florian Jessberger, 4. Auflage 2016, erschienen im Mohr Siebeck Verlag, Tübingen, XLIII, 937 Seiten, 129,00 €.
description: Studentische Zeitschrift für Rechtswissenschaft Heidelberg – Wissenschaft Online, Nr. 2 (2017): StudZR-WissOn
On determinant expansions for Hankel operators
Creators: name: Blower, Gordon
name: Chen, Yang
Publisher: name: arXiv
Year: 2019
Subjects: subject: Functional Analysis (math.FA)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 47B35

description: Let $w$ be a semiclassical weight which is generic in Magnus's sense, and $(p_n)_{n=0}^\infty$ the corresponding sequence of orthogonal polynomials. The paper expresses the Christoffel--Darboux kernel as a sum of products of Hankel integral operators. For $ψ\in L^\infty (i{\mathbb R})$, let $W(ψ)$ be the Wiener-Hopf operator with symbol $ψ$. The paper gives sufficient conditions on $ψ$ such that $1/\det W(ψ)W(ψ^{-1})=\det (I-Γ_{ϕ_1}Γ_{ϕ_2})$ where $Γ_{ϕ_1}$ and $Γ_{ϕ_2}$ are Hankel operators that are Hilbert--Schmidt. For certain $ψ$, Barnes's integral leads to an expansion of this determinant in terms of the generalised hypergeometric ${}_nF_m$. These results extend those of Basor and Chen [2], who obtained ${}_4F_3$ likewise. The paper includes examples where the Wiener--Hopf factors are found explicitly.
description: 30 pages
Cryptotendipes undetermined
Creators: name: Armitage, Brian J.
name: Andersen, Trond
name: Giłka, Wojciech
name: Castillo Sánchez, Kayla N.
name: Ríos González, Tomás A.
name: Aguirre, Yusseff P.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Cryptotendipes
Cryptotendipes undetermined

description: Cryptotendipes sp. *
Material examined. Panama, Chiriquí Province, Cuenca 108, Boquete District, Quebrada Grande, Valle Escondido, Condo unit 157-G, 5 males, 3 April 2022, UV light trap, leg B. Armitage.
description: Published as part of Armitage, Brian J., Andersen, Trond, Giłka, Wojciech, Castillo Sánchez, Kayla N., Ríos González, Tomás A. & Aguirre, Yusseff P., 2025, The Diptera of Panama. II. A first benchmark for the family Chironomidae, pp. 201-240 in Zootaxa 5613 (2) on page 209, DOI: 10.11646/zootaxa.5613.2.1, http://zenodo.org/record/15224174
Supersaturation for subgraph counts
Creators: name: Cutler, Jonathan
name: Nir, JD
name: Radcliffe, A. J.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: The classic extremal problem is that of computing the maximum number of edges in an $F$-free graph. In the case where $F=K_{r+1}$, the extremal number was determined by Turán. Later results, known as supersaturation theorems, proved that in a graph containing more edges than the extremal number, there must also be many copies of $K_{r+1}$. Alon and Shikhelman introduced a broader class of problems asking for the maximum number of copies of a graph $T$ in an $F$-free graph. In this paper, we determine some of these generalized extremal numbers and prove supersaturation results for them.