Additional file 1 of Comparing the diagnostic performance of QuantiFERON-TB Gold Plus with QFT-GIT, T-SPOT.TB and TST: a systematic review and meta-analysis
Creators: name: Zhang, Yu
name: Zhou, Guozhong
name: Shi, Wei
name: Shi, Weili
name: Hu, Meijun
name: Kong, Defu
name: Long, Rong
name: He, Jian
name: Chen, Nan
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Table S1. PRISMA checklist. Table S2. Search strategy. Table S2. Search strategy. Table S3. Inclusion and partial exclusion for patients with active TB. Table S4. Inclusion and partial exclusion for populations with very low risk of TB exposure. Table S5. Inclusion and partial exclusion for high-risk populations. Table S6. Populations considered high-risk. Table S7. Details of excluded criteria. Table S8. QUADAS-2 adapted quality assessment criteria for patients with active TB. Table S9. Quality score of 12 studies for patients with active TB. Table S10. QUADAS-2 adapted quality assessment criteria for populations with very low risk of TB exposure. Table S11. Quality score of 7 studies for populations with very low risk of TB exposure. Table S12. QUADAS-2 adapted quality assessment criteria for high-risk groups. Table S13. Quality score of 31 studies for high-risk groups. Table S14. Reasons for exclusion of 42 studies that were read in full-text review. Table S15. Characteristics of the 12 studies included in the sensitivity analysis. Table S16. Characteristics of the 7 studies included in the specificity analysis. Table S17. Characteristics of the 31 studies included in the positive rates. Table S18. Linearregression test of funnel plot asymmetry results of QFT-PLUS compared to QFT-GIT, T-SPOT.TB and TST in three populations. Figure S1. Forest plot of studies estimating the sensitivity of QFT-Plus (A) and QFT-GIT (B) in patients with active tuberculosis. Figure S2. Forest plot of studies estimating the sensitivity of QFT-Plus (A) and T-SPOT.TB (B) in patients with active tuberculosis. Figure S3. Forest plot of studies estimating the specificity of QFT-Plus (A) and QFT-GIT (B) in populations with very low risk of TB exposure. Figure S4. Forest plot of studies estimating the specificity of QFT-Plus (A) and T-SPOT.TB (B) in populations with very low risk of TB exposure. Figure S5. Forest plot of studies estimating the specificity of QFT-Plus (A) and TST (B) in populations with very low risk of TB exposure. Figure S6. Forest plot of studies estimating the positive rate Plus (A) and QFT-GIT (B) in high-risk populations. Figure S7. Forest plot of studies estimating the positive rate of QFT-Plus (A) and T-SPOT.TB (B) in high-risk populations. Figure S8. Forest plot of studies estimating the positive rate of QFT-Plus (A) and TST (B) in high-risk populations. Figure S9. Forest plot of studies estimating the sensitivity in patients with active tuberculosis for age of the participants (A), TB burden of the areas (B) and number of participants (C) subgroup analysis of QFT-PLUS compared with QFT-GIT. Figure S10. Forest plot of studies estimating the sensitivity in patients with active tuberculosis for number of participants subgroup analysis of QFT-PLUS compared with T-SPOT.TB. Figure S11. Forest plot of studies estimating the Specificity in populations with very low risk of TB exposure for TB burden of the areas (A) and number of participants (B) subgroup analysis of QFT-PLUS compared with QFT-GIT. Figure S12. Forest plot of studies estimating the positive rate in high-risk populations for age of the participants (A), TB burden of the areas (B), number of participants (C) and population (D)subgroup analysis of QFT-PLUS compared with QFT-GIT. Figure S13. Forest plot of studies estimating the positive rate in high-risk populations for age of the participants (A), TB burden of the areas (B), number of participants (C) and population (D)subgroup analysis of QFT-PLUS compared with T-SPOT.TB. Figure S14. Forest plot of studies estimating the positive rate in high-risk populations for age of the participants (A), TB burden of the areas (B), number of participants (C) and population (D)subgroup analysis of QFT-PLUS compared with TST. Figure S15. Sensitivity analysis of QFT-PLUS compared to QFT-GIT (A) and T-SPOT.TB (B) in patients with active TB. Figure S16. Sensitivity analysis of QFT-PLUS compared to QFT-GIT (A), T-SPOT.TB (B) and TST(C) in populations with very low risk of TB exposure. Figure S17. Sensitivity analysis of QFT-PLUS compared to QFT-GIT (A), T-SPOT.TB (B) and TST(C) in high-risk populations. Figure S18. Funnel plot of QFT-PLUS compared to QFT-GIT in patients with active TB. Figure S19. Funnel plot of QFT-PLUS compared to QFT-GIT (A) and TST (B) in high-risk populations.