cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Comparison of criteria used to access carcinogenicity in CPANN QSAR models versus the knowledge-based expert system Toxtree
Creators: name: N. Fjodorova
name: M. Novič
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: The primary goal of this study was to describe and compare the criteria used to assess carcinogenic activity. The statistically-based predictive quantitative structure–activity relationship (QSAR) models based on the counter propagation artificial neural network (CPANN) algorithm, and knowledge-based expert systems based on a decision tree structural alert (SA) approach (Toxtree application), were considered. The integration of the QSAR (CPANN models) and SAR (Toxtree SA application) approach contributed to the mechanistic understanding of the QSAR model considered. The mapping technique inherent to CPANN Kohonen enables us to relate the similarities or dissimilarities within a congeneric set of chemicals with particular SAs for carcinogenicity. The focus of our investigations was the similarities and dissimilarities of the features used in the QSAR and SAR methods. Due to the complexity of the carcinogenic endpoint, the integration of different approaches allows the models to be improved and provides a valuable technique for evaluating the safety of chemicals.
Cannabis concerns: Increased potency, availability and synthetic analogues
Creators: name: Downey, Luke
name: C. Verster, Joris
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 520201
subject: Behavioural genetics
classificationCode: 520202
subject: Behavioural neuroscience
classificationCode: 520203
subject: Cognitive neuroscience
classificationCode: 520205
subject: Psychopharmacology
classificationCode: 520206
subject: Psychophysiology
classificationCode: 520207
subject: Social and affective neuroscience
classificationCode: 520301
subject: Clinical neuropsychology
classificationCode: 520401
subject: Cognition
classificationCode: 520403
subject: Learning, motivation and emotion

description: Over the past 10 to 15 years, the evidence concerning the consequences of cannabis smoking has detailed a number of negative health outcomes. Over the same period, a wide variety of alternative cannabis products (synthetic cannabis and cannabis extracts) have been developed and consumed for a variety of purposes. Whilst the impact of cannabis smoking on behavior in the short-term, and the psychiatric, behavioral, physiological effects of extended usage of cannabis in the longer term have been observed to produce a number of societally and individually concerning outcomes; consumption of cannabis recreationally, continues. Despite cannabis being considered a relatively innocuous recreational drug, current evidence suggests it can adversely impact mental health. Sustained use of cannabis has been shown to significantly increase the risk of developing schizophrenia and other psychiatric disorders (Szoke et al. 2014). Possibly more concerning, the legalization of cannabis in some countries, the approval of cannabis products for usage to treat symptoms associated with medical conditions, and the development of synthetic cannabinoid products provides increased avenues for people to expose themselves to cannabis and its psychoactive effects.
A new alkaloid glycoside from the rhizomes of Aristolochia fordiana
Creators: name: Zhongbo Zhou
name: Jianguang Luo
name: Pan, Ke
name: Lingyi Kong
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: A new alkaloid glycoside named fordianoside (1), together with three known compounds arabinothalictoside (2), 6-O-p-coumaroyl-β-fructofuranosyl-(2 → 1)-α-d-glucopyranoside (3) and 4-[formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl] butanoic acid (4), was isolated from the rhizomes of Aristolochia fordiana. The structure of 1 was established as (1S)-1,2,3,4-tetrahydro-7-hydroxy-1-[(4-hydroxybenzyl) methyl]-2,2-dimethyl-8-O-isoquinolinyl β-d-glucopyranoside by using chemical and spectroscopic methods including HR-ESI-MS, 1D and 2D NMR.
Driving while hungover: The necessity of biomarkers of the alcohol hangover state
Creators: name: Verster, Joris
name: Van De Loo, Aurora J.A.E.
name: Downey, Luke
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 520201
subject: Behavioural genetics
classificationCode: 520202
subject: Behavioural neuroscience
classificationCode: 520203
subject: Cognitive neuroscience
classificationCode: 520205
subject: Psychopharmacology
classificationCode: 520206
subject: Psychophysiology
classificationCode: 520207
subject: Social and affective neuroscience
classificationCode: 520301
subject: Clinical neuropsychology
classificationCode: 520401
subject: Cognition
classificationCode: 520403
subject: Learning, motivation and emotion

description: Abstract not available.
Comparison of criteria used to access carcinogenicity in CPANN QSAR models versus the knowledge-based expert system Toxtree
Creators: name: N. Fjodorova
name: M. Novič
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: The primary goal of this study was to describe and compare the criteria used to assess carcinogenic activity. The statistically-based predictive quantitative structure–activity relationship (QSAR) models based on the counter propagation artificial neural network (CPANN) algorithm, and knowledge-based expert systems based on a decision tree structural alert (SA) approach (Toxtree application), were considered. The integration of the QSAR (CPANN models) and SAR (Toxtree SA application) approach contributed to the mechanistic understanding of the QSAR model considered. The mapping technique inherent to CPANN Kohonen enables us to relate the similarities or dissimilarities within a congeneric set of chemicals with particular SAs for carcinogenicity. The focus of our investigations was the similarities and dissimilarities of the features used in the QSAR and SAR methods. Due to the complexity of the carcinogenic endpoint, the integration of different approaches allows the models to be improved and provides a valuable technique for evaluating the safety of chemicals.
A new alkaloid glycoside from the rhizomes of Aristolochia fordiana
Creators: name: Zhongbo Zhou
name: Jianguang Luo
name: Pan, Ke
name: Lingyi Kong
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: A new alkaloid glycoside named fordianoside (1), together with three known compounds arabinothalictoside (2), 6-O-p-coumaroyl-β-fructofuranosyl-(2 → 1)-α-d-glucopyranoside (3) and 4-[formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl] butanoic acid (4), was isolated from the rhizomes of Aristolochia fordiana. The structure of 1 was established as (1S)-1,2,3,4-tetrahydro-7-hydroxy-1-[(4-hydroxybenzyl) methyl]-2,2-dimethyl-8-O-isoquinolinyl β-d-glucopyranoside by using chemical and spectroscopic methods including HR-ESI-MS, 1D and 2D NMR.
Social ideological influences on reported food consumption and BMI
Creators: name: Wang, Wei C.
name: Worsley, Anthony
name: Cunningham, Everarda
Publisher: name: Swinburne
Year: 2024

description: The purpose of this study was to investigate relationships between ideological beliefs, perceptions of the importance of health behaviours, health attitudes, food consumption, and Body Mass Index (BMI). A behavioural model was hypothesized based on the Theory of Reasoned Action (Fishbein & Ajzen, 1975). A survey was conducted among shoppers aged between 40 and 70 years at Eastland Shopping Centre, Melbourne, Australia. The hypothesized model was tested with this empirical data (n = 410) for younger (n = 151) and older (n = 259) age groups using structural equation modelling. The findings generally support the study hypotheses. For both groups, egalitarianism had a direct and positive influence on perceptions of the importance of health behaviours. Materialism and masculinity impacted negatively on health attitudes, which positively influenced importance of health behaviours. Perceptions of importance of health behaviours impacted positively on the consumption of healthy foods such as vegetables and fruits, but negatively on consumption of unhealthy foods including sweets and fats. However, BMI was significantly influenced by the consumption of unhealthy foods (e.g., sugar and fats) only for the younger age group. Hence, the associations between beliefs, attitudes, consumption behaviours, and BMI outcomes differed between younger and older age populations. Social ideological beliefs appear to influence health attitudes and thereafter, the consumption of healthy and unhealthy foods and BMI via different pathways.
Anatomy of low carbon retrofits: evidence from owner-occupied Superhomes
Creators: name: Fawcett, Tina
name: Killip, Gavin
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: A small number of ‘Superhome’ owners in the UK have renovated their homes to reduce CO2 emissions by 60% or more. Superhome owner-occupiers, their homes and various aspects of their retrofit are characterized including the timing, planning, motivation, costs and interactions with professionals, and lessons drawn from this specialized group for the wider population. Research is based on a survey of 57 Superhome owners and 14 more detailed interviews. Compared with typical owner-occupiers, Superhome owners are on average younger, better educated, living in larger household groups and larger homes, and have higher incomes. However, there is considerable variation between households. Two main routes to retrofit were identified: planned and emergent, with emergent retrofits taking longer to complete, stretching over many years in some cases. Householder levels of knowledge and involvement in planning and managing the retrofit were high. Most commonly, paid professionals did most or some of the retrofit work, but many projects included some DIY. Significantly, their decisions are not made as ‘rational economic actors’; instead motivations were multiple and included environmental concern, desire for improved comfort and living standards, reducing waste and saving on energy costs. Questions for further research are identified, as are suggestions for policy development.
title: Perceptions of the Built Environment Among Older Adults Who Live in Age-Restricted Communities Compared to Those Who Do Not in Southern Nevada
Creators: name: Annan, Sandra
Publisher: name: University of Nevada, Las Vegas
Year: 2020

description: As Americans are living longer, there has been exponential growth in the number of older adults. Growth in the aging population has created unique challenges. As seniors age, they face many changes in their health, financial stability, and lifestyle, making it challenging to remain independent. The inability to remain independent can be a stressful and depressing experience for older adults. Studies show that most seniors prefer to stay in their current living environment as they age, or age in place, rather than move into senior housing or other available housing options designed for aging. This study investigates how perceptions about built environment features that facilitate aging in place differ among seniors who live in age-restricted communities (n=589) compared to those who do not live in age-restricted communities (n=46). Chi-Square test of association revealed that perceptions differ for these three built environment features: amenities within walking distance (p = 0.026; χ2= 4.945), safety from crime (p = 0.003; χ2= 8.770), and safety from traffic (p = 0.001; χ2= 0.001), with those living in non-age-restricted communities more likely to perceive amenities within walking distance and safety from crime and traffic. Binary logistic regression models examining factors associated with perceptions of built environment attributes that facilitate aging in place were statistically significant (p≤0.05) for all eight built environment features. Statistically significant factors found in most models were connection to the community, ambulatory disability, non-age restricted communities, and loneliness. Public health professionals working with older adults should target interventions aimed at improving loneliness and community connections, as they may facilitate aging in place. Additionally, particular attention should be paid to the needs of older adults with a disability so that they may also be able to age in place. Future studies should aim to better understand the most effective way to address these issues.
Anatomy of low carbon retrofits: evidence from owner-occupied Superhomes
Creators: name: Fawcett, Tina
name: Killip, Gavin
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: A small number of ‘Superhome’ owners in the UK have renovated their homes to reduce CO2 emissions by 60% or more. Superhome owner-occupiers, their homes and various aspects of their retrofit are characterized including the timing, planning, motivation, costs and interactions with professionals, and lessons drawn from this specialized group for the wider population. Research is based on a survey of 57 Superhome owners and 14 more detailed interviews. Compared with typical owner-occupiers, Superhome owners are on average younger, better educated, living in larger household groups and larger homes, and have higher incomes. However, there is considerable variation between households. Two main routes to retrofit were identified: planned and emergent, with emergent retrofits taking longer to complete, stretching over many years in some cases. Householder levels of knowledge and involvement in planning and managing the retrofit were high. Most commonly, paid professionals did most or some of the retrofit work, but many projects included some DIY. Significantly, their decisions are not made as ‘rational economic actors’; instead motivations were multiple and included environmental concern, desire for improved comfort and living standards, reducing waste and saving on energy costs. Questions for further research are identified, as are suggestions for policy development.
Assessment of Macular Parameter Changes in Patients with Keratoconus Using Optical Coherence Tomography
Creators: name: Sahebjada, Srujana
name: Islam, Amirul
name: Wickremasinghe, Sanj
name: Daniell, Mark
name: Baird, Paul N.
Publisher: name: Swinburne
Year: 2024

description: Keratoconus is typically diagnosed through changes at the anterior ocular surface. However, we wished to assess if macular parameter changes might also occur in these patients. We assessed posterior changes through the use of optical coherence tomography and compared to a nonkeratoconus patient group. All subjects underwent clinical examination including macular thickness measurements. The generalized estimation equation model was used to estimate the means and compare the differences in various measurements between keratoconus and nonkeratoconus patients. A total of 129 keratoconus eyes of 67 cases and 174 nonkeratoconus eyes of 87 controls were analysed. Keratoconus individuals presented with a significantly greater mean retinal thickness in the central fovea, inner, and outer macula compared to the nonkeratoconus group (p <0.05). In addition, individuals presenting with the early signs of keratoconus had significantly greater inner and outer macular volume compared to the nonkeratoconus group (p <0.05). This study indicates the retina appears to thicken at the fovea and macula and had increased macular volume in keratoconus individuals compared to nonkeratoconus individuals. Thus we posit that structural retinal changes exist in keratoconus eyes that are additional to those typically seen in the anterior segment.
RESISTIRE D6.1 Report on solutions cycle 1
Creators: name: Živković, Igor
name: Kerremans, Aart
name: Denis, Alain
name: Cibin, Roberto
name: Linková, Marcela
name: Aglietti, Claudia
name: Cacace, Marina
name: Strid, Sofia
name: Callerstig, Anne-Charlotte
name: Axelsson, Tobias
name: Schrodi, Colette
name: Braun, Claire
name: Romeo, Grace
Publisher: name: Zenodo
Year: 2021
Subjects: COVID-19, gender+, inequalities, policy recommendations, research agenda, intersectional approach,

description: This report gives an overview of the further development of the action-ideas that came out of the Open Studios and how they were further combined with results of the research activities of the first cycle. They have been developed into Operational Recommendations, Pilot Projects and an Agenda for Future Research. The Operational Recommendations, designed as RESISTIRÉ Factsheets, focus on eight topics: gender mainstreaming, gender-balanced decision-making, a gender equality and diversity plan for hospitals, inclusive green spaces/commons, care and work-life balance, gender-based violence (on the European level and the national/local level), and telework. The Factsheets provide a brief overview of how COVID-19 has made visible or reinforced existing inequalities in the concerning theme, show personal stories of people affected by them, and give examples of inspiring policies to mitigate these inequalities. Finally, the Factsheets list several policy recommendations that would address the inequalities. The Pilot Projects are a selection of three action-ideas, that have been developed into project concepts that would address some of the inequalities that RESISTIRÉ has researched. The three selected project concepts are Employers Who Care, Green Spaces as Caring Ecosystems, and the Caring Workspaces. These project concepts have been designed and refined based on the input of the Open Studios, as well as other experts knowledgeable on the topic. A public call will be launched, whereby interested organisations can apply to lead the project. Finally, the Agenda for Future Research consists of four domains, which contain an analysis of previous findings from the RESISTIRÉ project, as well as an identification of research gaps. It also outlines which research questions and topics future research should address, and what questions RESISTIRÉ will focus on in the second cycle.
Knowledge integration and Indigenous planning in the Philippines
Creators: name: Ibanez, Jayson Carungay
Publisher: name: Charles Darwin University
Year: 2014

description: Knowledge integration projects involving Indigenous peoples are commonly criticized on equity issues and for further disempowering some groups within the Indigenous collective. These critiques arise because attention to Indigenous worldviews, values and aspirations is often limited with few benefits accruing to Indigenous knowledge-holders from the process. Practices that engage social justice and cultural empowerment principles offer one solution. I investigated this using Indigenous planning in the Philippines as an heuristic lens. The thesis first frames a working definition of ‘knowledge integration’ based on critical analyses that highlight the importance of ‘power’ differentials. A review of ecological knowledge among Philippine traditional societies and the role that informal institutions perform in social reproduction also shows that the Indigenous component of knowledge to be integrated is strongly place-based. However, content analysis of Indigenous plans from Mindanao showed little acknowledgement of and engagement with Indigenous ecological knowledge or deployment of cultural empowerment principles. Both the literature and Indigenous peoples’ perceptions suggest alternative instrumental and value rationalities about the “right way” to plan. Out of these data, a village-based Indigenous planning process was developed and tested in three villages. The process framework merges extra-local planner knowledge with that of Indigenous participants, while mindful of disparate worldviews, social resources, needs and priorities, and standards of respect in relationships between knowledge holders. The process harnesses the ‘best of both’ knowledge systems, but more reflexivity, action and commitment is expected from planners and their institutions. The planning process and the general demeanor of facilitators resulted in overall agreement about its effectiveness and value. Sustainability of the process, however, depends on the commitment of planners and their institutions to see planning through to implementation. In the Philippines, this means mainstreaming the process as complementary to the statutory ADSDPP framework before centralized planning occurs at the larger ancestral domain scale.
The green light on ketamine: Considerations for on-road safety
Creators: name: Hayley, Amie
name: Stough, Con
name: C. Verster, Joris
name: van de Loo, Aurora J. A. E.
name: Downey, Luke
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 520201
subject: Behavioural genetics
classificationCode: 520202
subject: Behavioural neuroscience
classificationCode: 520203
subject: Cognitive neuroscience
classificationCode: 520205
subject: Psychopharmacology
classificationCode: 520206
subject: Psychophysiology
classificationCode: 520207
subject: Social and affective neuroscience
classificationCode: 520301
subject: Clinical neuropsychology
classificationCode: 520401
subject: Cognition
classificationCode: 520403
subject: Learning, motivation and emotion

description: Ketamine (2-(2-chlorophenyl)-2-(methylamino) (cyclohexanone) is a phenylcyclidine derivative originally developed in the 1960’s as a medication to initiate and maintain optimum anaesthesia in veterinary and paediatric surgery [1]. Ketamine functions as an N-methyl-d-aspartate (NMDA) receptor antagonist, and in low or sub-aesthetic doses, has proven efficacy as an analgesic, sedative, and novel antidepressant [2]. The administration of ketamine reliably produces dose-related deficits in several functional cognitive domains, and the associated psychoactive properties of the substance have been described in some detail [3-5]. Despite this, the impact on translatable facets of neurobehavioural functioning associated with ketamine use, such as driving ability, is not well described, and thus assumptions regarding the implications of the use of this drug on measures of traffic safety are equivocal [6]. Epidemiological studies have noted an increase in both the clinical application and concurrent recreational use of ketamine, and thus effective assessments of both the direct and peripheral effects of this substance are of high clinical importance.
A construção de uma imagem política: aspectos da administração imperial de Tibério nos Anais de Tácito
Creators: name: Gonçalves, Ana Teresa Marques
name: Campos, Rafael Da Costa
Publisher: name: Ágora. Estudos Clássicos em Debate
Year: 2009

description: Nosso interesse neste artigo é estabelecer algumas revisões sobre aspectos da administração imperial de Tibério César Augusto (14 – 37 d.C.), por meio de uma leitura dos eventos políticos descritos por Públio Cornélio Tácito em seus Anais. É importante ressaltarmos que, ao contrário de uma primeira impressão perceptível na leitura da fonte, podemos afirmar que este Imperador não foi negligente com a difusão de sua imagem política, tampouco indiferente à forma como esta era assimilada pela população imperial tanto na Cidade de Roma quanto nas províncias. Esta conside-ração é importante por relacionar-se com uma latente necessidade no desenvolvi-mento de formas de conferência de autoridade e legitimidade ao seu governo, inserido em um momento de transição e consolidação de uma nova estrutura política. Mais ainda, esta preocupação, apesar de não ter surgido com seu antecessor Otávio Augusto, mas perceptível já com o ditador Júlio César em 49 a.C., foi um aspecto primordial de seu Principado, especialmente se considerarmos a existência de um momento histórico de estabelecimento e consolidação de uma nova forma de governo, que vinha para suplantar outra, minada por uma sucessão de conflitos civis e disputas políticas entre facções da aristocracia republicana.
description: Ágora. Estudos Clássicos em Debate, No 11 (2009)
Virgilio y Ovidio en las epopeyas españolas del siglo XIX: el episodio de la Fama (A. 4.173-197; Met. 12.39-63) en los últimos vestigios del género
Creators: name: Villalba De La Güida, Israel
Publisher: name: Ágora. Estudos Clássicos em Debate
Year: 2009

description: El concepto de rumor, noticia o presagio sufre un proceso de alegorización a lo largo de toda la literatura grecolatina para pasar a convertirse en un personaje divino con unas características y un protocolo de actuación concretos. En este articulo se reseña la pervivencia literaria del personaje en las literaturas europeas más importantes desde el siglo XVI al XIX, — centrándonos especialmente en la poesía épica española —, así como se subraya el grado de filiación exacta, ya con los clásicos ya por medio de otros poetas — Ariosto, Tasso o Camões —, entre los textos. Con ello, se quiere aportar la novedad de un estudio sistemático — hasta ahora no tenido en cuenta por la crítica — que muestre la gestación del personaje de la Fama y su posterior fortuna literaria en los últimos coletazos del género épico, tales como: La Iberíada — Ramón de Valvidares (1813) —, El moro expósito — Ángel Saavedra (1834), Pelayo — José de Espronceda (1825), o La Colombíada — Felipe Trigo y Gálvez (1885).
description: Ágora. Estudos Clássicos em Debate, No 11 (2009)
A family of double-layered coordination polymers containing Cd2+, N,O-chelating ligands, and bridging SCN− and Cl−
Creators: name: Srinivasan, Krishnan
name: Ayyasami Kathiresan
name: Subbaiah Govindarajan
name: Aughey, Joel T.
name: Harrison, William T.A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: The syntheses, structures, and characterization (IR, TGA/DTA) of a family of layered coordination polymers containing Cd2+, bridging anions (SCN− and Cl−), and chelating C2H6N2O2 methyl carbazate (mc) and C3H8N2O2 ethyl carbazate (ec) ligands are described, viz: Cd(SCN)2(C2H6N2O2), Cd(SCN)Cl(C2H6N2O2), Cd(SCN)2(C3H8N2O2), and Cd(SCN)Cl(C3H8N2O2). Single-crystal structures show them to contain distorted CdN3OS2 (for the thiocyanate) and CdN2OCl2S (for the thiocyanate/chloride) octahedra, in which the mc and ec ligands adopt an N,O-bidentate coordination mode, and the four anions bridge adjacent metal ions, which leads to polymeric sheets built up from double-octahedral layers propagating in the (1 0 0) plane. The topological linkage of the metal ions, which is the same in each structure, can be described as a distorted hexagonal grid. The crystal structures are completed by weak N–H⋯O, N–H⋯N, N–H⋯Cl, and N–H⋯S hydrogen bonds, which all occur within the (1 0 0) polyhedral layers.
RESISTIRE D5.2 Report on open studios cycle 1
Creators: name: Kerremans, Aart
name: Živković, Igor
name: Denis, Alain
Publisher: name: Zenodo
Year: 2021
Subjects: COVID-19, inequalities, gender+, open studios, research agenda, recommendation

description: This report provides an overview of the four Open Studios that were conducted in the first cycle of the RESISTIRÉ project and their respective results. The Open Studios constitute the co-creation step in the RESISTIRÉ process, with results from the first research cycle (WP2-4) being interpreted in this multidisciplinary format. The Open Studios are action-oriented, which means that their ultimate output consists of ideas for concrete action (which can be put into practice through pilot projects), input for recommendations to reshape policies, and unanswered questions (missing insights or knowledge) that can form the foundation of a future research agenda.
Aires A. Nascimento e Maria Cristina C. M. S. Pimentel, Ovídio: exílio e poesia. Leituras ovidianas no bimilenário da “relegatio”, Lisboa, Centro de Estudos clássicos, 2007 (183 pp.).
Creators: name: Mora, Carlos De Miguel
Publisher: name: Ágora. Estudos Clássicos em Debate
Year: 2009

description: Sem resumo disponível.
description: Ágora. Estudos Clássicos em Debate, No 11 (2009)
Disposition Outcomes Following Prehospital Use of Naloxone in a Large Metropolitan City in the United States
Creators: name: Langabeer, James R.
name: Bakos-Block, Christine
name: Cohen, A. Sarah
name: Alam, Ishmam
name: Gopal, Bhanumathi
name: Cardenas-Turanzas, Marylou
name: Weltge, Arlo F.
name: Persse, David
name: Champagne-Langabeer, Tiffany
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Mental Health

description: During a drug overdose, research suggests individuals may not call 9-1-1 out of fear of criminal justice concerns. Of those that call, research is inconclusive about the disposition of the emergency transport. We evaluated transport outcomes for adults with opioid-related overdose in the Emergency Medical Services (EMS) of a large metropolitan city in the United States. We reviewed the EMS incident report database from the patient care record system for years 2018 to 2022. We queried all records, searching for relevant terms, and two reviewers cross-checked the database to identify cases that did not result in death at the scene. Study outcome was defined as hospital transportation or no transportation. Multivariable logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (95% CI) for hospital transport with patient age, sex, race and ethnicity as the independent variables. We identified 5,482 cases of nonfatal opioid-related overdose. Of these, 4,984 (90.9%) were transported to the hospital; 37 (0.7%) were placed in police custody; 304 (5.5%) were not transferred; and 157 (2.9%) had unknown outcomes. Among 5,288 with data on the transport outcome, the majority were male (65%), and the highest proportion were White (39%). Compared to those who were not transported, each 1-year increase in age was related to a 2% increase in the odds of transportation (OR: 1.02, 95% CI: 1.01-1.02). Compared to White patients, Black and Hispanic patients were 43% OR: 1.43, 95% CI: 1.07-1.90) and 44% (OR: 1.44, 95% CI: 1.03-2.00) more likely to be transported. Individuals with suspected opioid-related overdose who call 9-1-1 are most often transported to the hospital. Current EMS procedures are successful at on-scene treatment and transportation; however, data on the long-term impact of opioid-related overdoses are still needed.
Disposition Outcomes Following Prehospital Use of Naloxone in a large metropolitan city in the United States
Creators: name: Langabeer, James R.
name: Bakos-Block, Christine
name: Cohen, A. Sarah
name: Alam, Ishmam
name: Gopal, Bhanumathi
name: Cardenas-Turanzas, Marylou
name: Weltge, Arlo F.
name: Persse, David
name: Champagne-Langabeer, Tiffany
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Mental Health

description: During a drug overdose, research suggests individuals may not call 9-1-1 out of fear of criminal justice concerns. Of those that call, research is inconclusive about the disposition of the emergency transport. We evaluated transport outcomes for adults with opioid-related overdose in the Emergency Medical Services (EMS) of a large metropolitan city in the United States. We reviewed the EMS incident report database from the patient care record system for years 2018 to 2022. We queried all records, searching for relevant terms, and two reviewers cross-checked the database to identify cases that did not result in death at the scene. Study outcome was defined as hospital transportation or no transportation. Multivariable logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (95% CI) for hospital transport with patient age, sex, race and ethnicity as the independent variables. We identified 5,482 cases of nonfatal opioid-related overdose. Of these, 4,984 (90.9%) were transported to the hospital; 37 (0.7%) were placed in police custody; 304 (5.5%) were not transferred; and 157 (2.9%) had unknown outcomes. Among 5,288 with data on the transport outcome, the majority were male (65%), and the highest proportion were White (39%). Compared to those who were not transported, each 1-year increase in age was related to a 2% increase in the odds of transportation (OR: 1.02, 95% CI: 1.01-1.02). Compared to White patients, Black and Hispanic patients were 43% OR: 1.43, 95% CI: 1.07-1.90) and 44% (OR: 1.44, 95% CI: 1.03-2.00) more likely to be transported. Individuals with suspected opioid-related overdose who call 9-1-1 are most often transported to the hospital. Current EMS procedures are successful at on-scene treatment and transportation; however, data on the long-term impact of opioid-related overdoses are still needed.
Exploring and validating heating dynamics in a radio-frequency electromagnetic field-based resonant chamber for mouse hyperthermia research
Creators: name: Jiao, Lijiao
name: Zhang, Tao
name: Gao, Peng
name: Zhou, Chao
name: Mei, Xiang
name: Zhang, Wenjuan
name: Lu, Yonghui
name: Zhang, Lei
name: Zhou, Zhou
name: Yu, Zhengping
name: He, Mindi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Science Policy

description: Mild whole-body hyperthermia has been shown to have anti-tumor effects through an immune-modulating mechanism. Before it is widely applied in the clinic, tremendous mechanistic research in animals is necessary to adhere to evidence-based principles. The radio frequency electromagnetic field (RF-EMF) based heating facility could be a good choice for hyperthermia treatment, but the heating characteristics of a facility, including structure design, electromagnetic and thermal dosimetry, and the biologic effects of hyperthermia, need to be well elucidated. Here, we reported the heating characteristic study on a resonant chamber (RC) excited by a 1800 MHz solid source. The EMF in the RC was stirred by 24 static reflectors, which resulted in the standard deviation of electric field intensity being below 3 dB in the EM homogeneity evaluation. For the exposure scenario, six free-moving mice were loaded into separate cases and exposed simultaneously in the RC. The EMF energy absorption and distribution in exposed mice were calculated with the 12-plane-waves method of numerical simulation. Different levels of core body temperature increment in exposed mice were achieved through regulation of the source output power. Overexpression of heat shock proteins (HSPs) was detected in the liver, lung and muscle, but not in the brain of the exposed mice. The levels of representative inflammatory cytokines in the serum, TNF-α and IL-10 increased post RC exposure. Based on the heating characteristic study and validation, the applied RC would be a qualified heating system for mild whole-body hyperthermia effect research in mice. Mild whole-body hyperthermia has potential anti-tumor effects by modulating the immune system. A radio frequency electromagnetic field (RF-EMF)-based heating facility emerges as a suitable option for hyperthermia treatment. However, a qualified heating facility for scientific research must elucidate its heating characteristics and validate the biological effects associated with hyperthermia. In this study, we report the characteristics of a rodent heating chamber using EMF energy. The special structure of the chamber not only achieved efficient EMF usage but also ensured the homogeneity in EMF spatial distribution, animal EM absorption, and EMF-caused biological effects. Our work may offer insights for designing a low-cost yet reliable heating facility for scientific research.
Legitimacy for large public libraries in the digital age
Creators: name: Waller, Vivienne
Publisher: name: Swinburne
Year: 2024

description: The purpose of this paper is to critically analyse recent developments in the relationship of large public libraries with digital technologies, suggesting a way of rethinking the future of large public libraries. This paper bases its critical analysis on a review of the literature and reference to specific cases. Historical quotes preceding sections augment the argument that many of the current concerns about digital technologies are not new issues for libraries. Issues around library take up of digital technology are continuations of debates that have occurred throughout the history of public libraries about the role of the library. In Australia, library policy makers are focusing on technology and an imagined user in an effort to prove the legitimacy of large public libraries to funding bodies, the library profession and library users. Such attempts seem doomed to fail. Public libraries need to be clear about their purpose as publicly funded institutions in the digital age. This requires a renewed understanding of a library's publics and a critical understanding of the nature of services available using digital technologies. This paper presents an alternative way of thinking about the future of large public libraries, with much of the discussion also relevant to local public libraries.
A Review on Technique in Managing Oil Palm Plantation towards a Digitalized Online 3D Application
Creators: name: Dr. Ruzinoor Che Mat
Publisher: name: figshare
Year: 2014
Subjects: Applied Computer Science

description: The oil palm industry has been well known as the backbone in Malaysian agriculture and still maintain as the main commodity exports. The research on oil palm industry has been growing gradually by utilizing various methods and technology to solve the problem in managing oil palm plantation. The aim of this paper is to review the technique in managing oil palm plantation towards a digitalized online 3D application. Various problems and techniques on managing oil palm plantation has been reviewed which involving various technology such as GIS, GPS, DBMS and hyperspectral. It was found that monitoring the characteristic of oil palm plantation is beneficial and important to oil palm planters. The new online 3D application for oil palm plantation management has a potential of assisting oil palm managers in making a decision, visualizing their plantation in online 3D environment, and managing their plantation effectively.
title: Current-Mode Photon-Counting Circuit with SiGe BiCMOS Input Stage
Creators: name: Arteaga, Gonzalo
Publisher: name: University of Nevada, Las Vegas
Year: 2020

description: Continued advances in photodetector technology have helped improve the imaging capabilities of LiDAR systems or other time-of-flight imaging efforts. As a major part of the receiver within a LiDAR system, the photodetector can offer features such as faster rise times, narrower pulse widths, or larger gains to help achieve greater timing resolution or sensitivity to faint light levels. These benefits, however, are contingent on the ability of the accompanying readout circuit to reliably process the fast, electrical signals generated by the photodetector. While common front-end circuits involve the use of feedback amplifiers, their stability can become a major concern at higher frequencies. In pursuit of an alternative topology, this thesis investigates the design of a current mode photon-counting circuit for LiDAR applications.

In this effort, four test circuits were explored which were based on the concept of a current comparator. The proposed circuit would compare the photodetector current signal with that of an adjustable reference current and generate a 1.8-V digital signal whenever one current magnitude exceeded the other. The design, simulation, and layout of the circuits were done using a 180-nm SiGe BiCMOS process, and the photodetector of interest was a microchannel plate photomultiplier tube (MCPPMT). To interface with the photodetector, the designs feature a BiCMOS regulated cascode (RGC) input stage which provides a low input impedance of about 2-ohms up to 500-MHz or, when used with a 47- ohm in-series matching resistor, about 50-ohms up to 2-GHz. The circuits can detect typical signals from the detector which include pulses that are 300-ps FWHM wide with a minimum height of 8-uA at count

rates up to 1-GHz. The corresponding output pulses from the designs had a delay which ranged from 0.9 to 1.2-ns. Each circuit had a static power consumption no more than 5.5-mW/ch with an anticipated dynamic power consumption substantially less than the target of 20-mW/ch.

Initial test results on the fabricated chip confirmed the basic function of the test circuits using lower frequency signals with amplitudes near 300-μA. Further testing will, however, be necessary to fully characterize the designs and to see how viable the proposed designs are for the intended application.
Morphological Operation on Printed Circuit Board (PCB) Reverse Engineering using MATLAB
Creators: name: Dr. Ruzinoor Che Mat
Publisher: name: figshare
Year: 2014
Subjects: Applied Computer Science

description: ABSTACT Image segmentation has been an important and challenging issue in the field of computer vision over decades. It plays a critical role for most image analysis tasks, such as object detection and recognition. The aim of this paper is to obtain segmented image of Printed Circuit Board (PCB)’s track using mathematical morphological operation. Morphological image analysis is based on the idea that images represent a collection of spatial patterns that can be analyzed based on some predefined patterns called structuring elements. Most basic morphological operation, dilation and erosion have been employed in this research. Detail elaboration on this method will be discussed and experimental results are presented.
Algumas obras de André de Resende, VOL. II (1529-1551). In honorem Dr. Miguel Pinto de Meneses – II. Edição, introdução e estudo de Manuel Cadafaz de Matos.
Creators: name: Pereira, Virgínia Soares
Publisher: name: Ágora. Estudos Clássicos em Debate
Year: 2009

description: Sem resumo disponível.
description: Ágora. Estudos Clássicos em Debate, No 11 (2009)
Duarte de Sande, S. I., Diálogo sobre a Missão dos Embaixadores Japoneses à Cúria Romana Coimbra, Imprensa da Universidade de Coimbra/Centro Científico e Cultural de Macau, 2009
Creators: name: Torrão, João Manuel Nunes
Publisher: name: Ágora. Estudos Clássicos em Debate
Year: 2009

description: Sem resumo disponível.
description: Ágora. Estudos Clássicos em Debate, No 11 (2009)
Estimation of power conversion efficiency up to 12% of nanocomposites of catechin and carboxylated graphene quantum dots doped/functionalised with boron as photosensitizers in DSSC applications
Creators: name: Alsmani, Nuha
name: Al-Qurashi, Ohoud S.
name: Wazzan, Nuha
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Hematology

description: The power conversion efficiency (PCE) of dye-sensitised solar cells (DSSCs) measures their solar energy conversion performance. With PCEs below 15%, significant energy loss occurs, leading researchers to seek improvements to reduce fossil fuel dependence and enhance DSSCs as an alternative energy source. However, predicting PCE theoretically is challenging due to its dependence on various parameters. In this work, the improved normal model was used to predict the PCE accurately using DFT and TD-DFT of four nanocomposites consisting of catechin natural compound attached to carboxylated graphene quantum dots (GQD) that have been further doped at the centre/edge and decorated with a boronic group. The nanocomposites have been adsorbed on a TiO2 cluster for PCE estimation. This is the first attempt of using decorated GQD with boronic groups in a DSSC and estimating its PCE. The results show that the PCE of catechin improved from 0.077% to the range of 3.96% – 12.61% (B1-CG-C@TiO2 – B2-CG-C@TiO2). This was due to the improved short-circuit current density (Jsc) and fill factor (FF) of all the nanocomposites and the improved open-circuit voltage (Voc) of all nanocomposites except B1-CG-C@TiO2 in comparison to catechin. This means all the designed nanocomposites are more promising candidates than catechin. HighlightsAdsorption at carboxyl group is the most stable site among hydroxyl and GQD base.The improved normal model gives accurate Voc results.All designed nanocomposites exhibited higher PCEs than isolated catechin.Edged doping exhibited the highest Voc, high Jsc, and highest PCE of 12.61%. Adsorption at carboxyl group is the most stable site among hydroxyl and GQD base. The improved normal model gives accurate Voc results. All designed nanocomposites exhibited higher PCEs than isolated catechin. Edged doping exhibited the highest Voc, high Jsc, and highest PCE of 12.61%.
A family of double-layered coordination polymers containing Cd2+, N,O-chelating ligands, and bridging SCN− and Cl−
Creators: name: Srinivasan, Krishnan
name: Ayyasami Kathiresan
name: Subbaiah Govindarajan
name: Aughey, Joel T.
name: Harrison, William T.A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: The syntheses, structures, and characterization (IR, TGA/DTA) of a family of layered coordination polymers containing Cd2+, bridging anions (SCN− and Cl−), and chelating C2H6N2O2 methyl carbazate (mc) and C3H8N2O2 ethyl carbazate (ec) ligands are described, viz: Cd(SCN)2(C2H6N2O2), Cd(SCN)Cl(C2H6N2O2), Cd(SCN)2(C3H8N2O2), and Cd(SCN)Cl(C3H8N2O2). Single-crystal structures show them to contain distorted CdN3OS2 (for the thiocyanate) and CdN2OCl2S (for the thiocyanate/chloride) octahedra, in which the mc and ec ligands adopt an N,O-bidentate coordination mode, and the four anions bridge adjacent metal ions, which leads to polymeric sheets built up from double-octahedral layers propagating in the (1 0 0) plane. The topological linkage of the metal ions, which is the same in each structure, can be described as a distorted hexagonal grid. The crystal structures are completed by weak N–H⋯O, N–H⋯N, N–H⋯Cl, and N–H⋯S hydrogen bonds, which all occur within the (1 0 0) polyhedral layers.
The relationship between public libraries and Google: Too much information
Creators: name: Waller, Vivienne
Publisher: name: Swinburne
Year: 2024

description: This article explores the implications of a shift from public to private provision of information through focusing on the relationship between Google and public libraries. This relationship has sparked controversy, with concerns expressed about the integrity of search results, the Google Book project, and Google the company. In this paper, these concerns are treated as symptoms of a deeper divide, the fundamentally different conceptions of information that underpin the stated aim of Google and libraries to provide access to information. The paper concludes with some principles necessary for the survival of public libraries and their contribution to a robust democracy in a rapidly expanding Googleverse.