cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Androgen deprivation therapy, comorbidity, cancer stage and mortality from COVID-19 in men with prostate cancer
Creators: name: Gedeborg, Rolf
name: Lindhagen, Lars
name: Loeb, Stacy
name: Styrke, Johan
name: Garmo, Hans
name: Stattin, Pär
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Androgens facilitate entrance of the severe acute respiratory syndrome coronavirus 2 into respiratory epithelial cells, and male sex is associated with a higher risk of death from corona virus disease (COVID-19). Androgen deprivation therapy (ADT) could possibly improve COVID-19 outcomes. In a case–control study nested in the Prostate Cancer data Base Sweden (PCBaSe) RAPID 2019, we evaluated the association between ADT and COVID-19 as registered cause of death in men with prostate cancer. Each case was matched to 50 controls by region. We used conditional logistic regression to adjust for confounders and also evaluated potential impact of residual confounding. We identified 474 men who died from COVID-19 in March–December 2020. In crude analyses, ADT exposure was associated with an increased risk of COVID-19 death (odds ratio [OR] 5.05, 95% CI: 4.18–6.10); however, the OR was substantially attenuated after adjustment for age, comorbidity, prostate cancer characteristics at diagnosis, recent healthcare use, and indicators of advanced cancer (adjusted OR 1.25, 95% CI: 0.95–1.65). If adjustment has accounted for at least 85% of confounding, then the true effect could be no more than a 5% reduction of the odds for COVID-19 death. The increased mortality from COVID-19 in men with prostate cancer treated with ADT was mainly related to high age, comorbidity, and more advanced prostate cancer. There was no evidence to support the hypothesis that ADT is associated with improved COVID-19 outcomes.
Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism
Creators: name: Selvin, E.
name: Pankow, J.S.
name: Köttgen, A.
name: Mei, H.
name: Nauck, M.
name: Pietzner, M.
name: Loomis, S.J.
name: Li, M.
name: Boerwinkle, E.
name: Morrison, A.C.
name: North, K.E.
name: Teumer, A.
name: Friedrich, N.
name: Maruthur, N.M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: 1,5-anhydroglucitol (1,5-AG) is a biomarker of hyperglycemic excursions associated with diabetic complications. Because of its structural similarity to glucose, genetic studies of 1,5-AG can deliver complementary insights into glucose metabolism. We conducted genome-wide association studies of serum 1,5-AG concentrations in 7,550 European ancestry (EA) and 2,030 African American participants (AA) free of diagnosed diabetes from the ARIC Study. Seven loci in/near EFNA1/SLC50A1, MCM6/LCT, SI, MGAM, MGAM2, SLC5A10, and SLC5A1 showed genome-wide significant associations (P < 5 × 10-8) among EA participants, five of which were novel. Six of the seven loci were successfully replicated in 8,790 independent EA individuals, and MCM6/LCT and SLC5A10 were also associated among AA. Most of 1,5-AG-associated index SNPs were not associated with the clinical glycemic markers fasting glucose or theHbA1c, and vice versa. Only the index variant in SLC5A1 showed a significant association with fasting glucose in the expected opposing direction. Products of genes in all 1,5-AG-associated loci have known roles in carbohydrate digestion and enteral or renal glucose transport, suggesting that genetic variants associated with 1,5-AG influence its concentration via effects on glucose metabolism and handling.
title: Тетралогия Е.Н.Чирикова «Жизнь Тарханова» как роман воспитания
Creators: name: Белукова, Виктория
Publisher: name: Новгородский государственный университет имени Ярослава Мудрого (НовГУ)
Year: 2022

description: Исследуются жанровое своеобразие тетралогии Е.Н.Чирикова «Жизнь Тарханова», а также признаки и особенности сюжета, позволяющие причислить данное произведение к жанру роман воспитания: становление центрального героя как личности, процесс его умственного и духовного формирования. Писатель на протяжении всего повествования показывает героя, Геннадия Тарханова, в динамике: герой меняется не только физически (взрослеет), но и изменяется его внутренний мир. Ключевым показателем этих изменений становится его меняющийся статус. Особо отмечены персонажи, направляющие воспитание главного героя.
title: Spin density matrix element extraction for the p°vector meson on hydrogen and deuterium targets at HERMES
Creators: name: Shearer, Craig
Publisher: name: University of Glasgow
Year: 2022

description: The HERMES experiment in Hamburg, Germany, consists of a large forward spectrometer which studies various physics processes related to the nucleon and its internal structure. The main focus of the analysis presented in this thesis is based on the angular decay distributions of the decay products of the ρ0 vector meson. By examining the angular decay of the outgoing decay products the Spin Density Matrix Elements (SDMEs) for the ρ 0 can be determined. The extraction of the ρ0 data sample from the raw HERMES output data is explained and the method used to extract exclusive, diffractive ρ0s is given. The analysis procedure and the method used to analyse the data samples is then explained with consideration given to the description of the method used to extract the spin density matrix elements. In the autumn of 2005 a new detector known as the Recoil Detector will be commissioned in the front region of the HERMES experiment. The Recoil Detector will advance the analysis presented in this thesis in some regards, ie the improved t-resolution at low t which will improve exclusive measurements including vector meson production. Several contributions to the Recoil Detector are presented in detail. In particular the research of the HELIX128-3.0 readout chip and its development towards the final readout of the silicon detector and the integration of the Recoil Detector into the Hermes Monte Carlo.
Effects of aqueous extracts of Acacia albida stem bark on Wistar albino rats infected with Trypanosoma evansi
Creators: name: Uche Samuel Ndidi
name: Ismaila Alhaji Umar
name: Aminu Mohammed
name: Cosmas Samuel
name: Oladeru, Amos Oladiran
name: Rahinat Nimma Yakubu
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Medicine

description: The effect of aqueous extract of Acacia albida stem bark was investigated in Wistar albino rats infected with Trypanosoma evansi. The extract showed highest reduction in parasitemia at the dose of 600 mg/kg body weight (bw). A dose of 300 mg/kg bw improved packed cell volume the most by 14.35%. The group treated with 150 and 600 mg/kg bw of the extract showed significant decrease (P P A. albida have antitrypanosomal activity against T. evansi infection.
The genetics of obesity and the metabolic syndrome
Creators: name: Hunt, S.C.
name: North, K.E.
name: Province, M.A.
name: Monda, K.L.
name: Kraja, A.T.
name: Rao, D.C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: In this review, we discuss the genetic architecture of obesity and the metabolic syndrome, highlighting recent advances in identifying genetic variants and loci responsible for a portion of the variation in components of the metabolic syndrome, namely, adiposity traits, serum HDL and triglycerides, blood pressure, and glycemic traits. We focus particularly on recent progress from large-scale genome-wide association studies (GWAS), by detailing their successes and how lessons learned can pave the way for future discovery. Results from recent GWAS coalesce with earlier work suggesting numerous interconnections between obesity and the metabolic syndrome, developed through several potentially pleiotropic effects. We detail recent work by way of a case study on the cadherin 13 gene and its relation with adiponectin in the HyperGEN and the Framingham Heart Studies, and its association with obesity and the metabolic syndrome. We provide also a gene network analysis of recent variants related to obesity and metabolic syndrome discovered through genome-wide association studies, and 4 gene networks based on searching the NCBI database.
Polymorphisms in DNA repair genes, recreational physical activity and breast cancer risk
Creators: name: Olshan, A.F.
name: Gammon, M.D.
name: Millikan, R.C.
name: Bradshaw, P.T.
name: Neugut, A.I.
name: Eng, S.M.
name: Terry, M.B.
name: Teitelbaum, S.L.
name: Mccullough, L.E.
name: Santella, R.M.
name: Rossner, P.
name: Franceschini, N.
name: Cleveland, R.J.
name: Crew, K.D.
name: Shen, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The mechanisms driving the inverse association between recreational physical activity (RPA) and breast cancer risk are complex. While exercise is associated with increased reactive oxygen species production it may also improve damage repair systems, particularly those that operate on single-strand breaks including base excision repair (BER), nucleotide excision repair (NER) and mismatch repair (MMR). Of these repair pathways, the role of MMR in breast carcinogenesis is least investigated. Polymorphisms in MMR or other DNA repair gene variants may modify the association between RPA and breast cancer incidence. We investigated the individual and joint effects of variants in three MMR pathway genes (MSH3, MLH1 and MSH2) on breast cancer occurrence using resources from the Long Island Breast Cancer Study Project. We additionally characterized interactions between RPA and genetic polymorphisms in MMR, BER and NER pathways. We found statistically significant multiplicative interactions (p < 0.05) between MSH2 and MLH1, as well as between postmenopausal RPA and four variants in DNA repair (XPC-Ala499Val, XPF-Arg415Gln, XPG-Asp1104His and MLH1-lle219Val). Significant risk reductions were observed among highly active women with the common genotype for XPC (OR = 0.54; 95% CI, 0.36-0.81) and XPF (OR = 0.62; 95% CI, 0.44-0.87), as well as among active women who carried at least one variant allele in XPG (OR = 0.46; 95% CI, 0.29-0.77) and MLH1 (OR = 0.46; 95% CI, 0.30-0.71). Our data show that women with minor alleles in both MSH2 and MLH1 could be at increased breast cancer risk. RPA may be modified by genes in the DNA repair pathway, and merit further investigation.
Appendix to BEH 3761
Creators: name: da Rocha, Sulamita M.C.
name: Magnusson, William E.
name: Rojas, Diana
name: Lima, Albertina P.
Publisher: name: Brill Online
Year: 2022
Subjects: Animal behaviour

description: Figure A1. Photograph of model in in the field. Figure A2. Photographs of examples of attack marks. From top to bottom: Bird attack, mammal attack, invertebrate attack. Table A1. Results of GLM and Tukey test between predation of each type of predator for colour category and location.
Role of BMI in the association of the TCF7L2 rs7903146 variant with coronary heart disease: The atherosclerosis risk in communities (ARIC) study
Creators: name: Monda, K.L.
name: Pankow, J.S.
name: Köttgen, A.
name: North, K.E.
name: Kucharska-Newton, A.M.
name: Boerwinkle, E.
name: Heiss, G.
name: Rosamond, W.D.
name: Bielinski, S.J.
name: Rea, T.D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: We examined the association of variation in the type 2 diabetes risk-conferring TCF7L2 gene with the risk of incident coronary heart disease (CHD) among the lean, overweight, and obese members of the Atherosclerosis Risk in Communities (ARIC) Study cohort. Cox proportional hazard regression analyses were performed using a general model, with the major homozygote as the reference category. For 9,865 whites, a significant increase in the risk of CHD was seen only among lean (BMI <25 kg/ m 2) individuals homozygous for the T allele of the TCF7L2 rs7903146 gene risk variant (hazard ratio 1.42; 95% CI 1.03,1.97; P=.01). No association was found among 3,631 blacks, regardless of BMI status. An attenuated hazard ratio was observed among the nondiabetic ARIC cohort members. This study suggests that body mass modifies the association of the TCF7L2 rs7903146 T allele with CHD risk.
title: In search of the Never-Never
title: the Northern Territory metaphor in Australian writing, 1837-1992
titleType: Subtitle
Creators: name: Dewar, Michelle Sue
Publisher: name: Charles Darwin University
Year: 1993

description: For more than one hundred and fifty years, the Northern Territory has been represented in Australian writing as a region of special significance. The process of defining the Northern Territory as a literary construct and the ensuing dialogue between outback and urban themes, focussed the writing within the debate concerning national identity. Territory literature embraces subjects arising from colonisation, attitudes to the environment and the place of Aborigines. These issues remain fundamental to establishing both an identity and legitimacy for non-Aboriginal settlers in Australia. The Northern Territory became the theatre where these unresolved issues could be played out. An examination of the social and intellectual climate of the periods through the lives of the authors, and the assumptions, images and themes of the books, reveals a progression of attitudes and values inherent in the settler culture. The literary construction of the Northern Territory became the metaphor for European occupation of Australia. The perseverance of the Northern Territory as a subject for Australian writing, apparently disproportionate to its population, geographic location, or economic significance, suggests that the metaphor remains relevant.
The Joint Effect of Typicality and Novelty on Aesthetic Pleasure for Product Designs: Influences of Safety and Risk
Creators: name: Thurgood, Clementine
name: Hekkert, Paul
name: Blijlevens, Janneke
Publisher: name: Swinburne
Year: 2024

description: While some studies have shown that people prefer typical product designs, others have shown that people also like product designs that are new. To reconcile these contradictory findings, the design principle, ‘Most Advanced, Yet Acceptable’ proposes that people prefer a balance of both typicality and novelty in product designs. As an explanation, we propose that typicality and novelty fulfil basic evolutionary needs for safety and exploration that still drive behaviour today, and that products are most preferred when they satisfy both of these needs simultaneously. We further propose that conditions of safety and risk will drive product preferences towards novelty and typicality, respectively. Overall, this research will provide insights into when and why aesthetic preferences for typicality or novelty occur.
2,3-Seco-2,3-dioxo-lyngbyatoxin A from a Red Sea strain of the marine cyanobacterium Moorea producens
Creators: name: Diaa T.A. Youssef
name: Shaala, Lamiaa A.
name: Mohamed, Gamal A.
name: Sabrin R.M. Ibrahim
name: Zainy M. Banjar
name: Badr, Jihan M.
name: McPhail, Kerry L.
name: Risinger, April L.
name: Mooberry, Susan L.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Microbiology
subject: Biochemistry

description: Chemical investigation of the organic extract of a Red Sea strain of the cyanobacterium Moorea producens has afforded 2,3-seco-2,3-dioxo-lyngbyatoxin A (1). Five known compounds including lyngbyatoxin A (2), majusculamides A and B (3 and 4), aplysiatoxin (5) and debromoaplysiatoxin (6) were also isolated. Their structures were elucidated by using HR-FAB-MS, 1D and 2D NMR analyses. The compounds were evaluated for antiproliferative activity against HeLa cancer cells. Lyngbyatoxin A (2) showed potent activity, with an IC50 of 9.2 nM, while 5 and 6 displayed modest activity with IC50 values of 13.3 and 3.03 μM, respectively. In contrast, compounds 1, 3 and 4 were inactive, with IC50 values greater than 50 μM. The lack of cytotoxicity for 2,3-seco-2,3-dioxo-lyngbyatoxin A (1) demonstrates that the indole moiety in lyngbyatoxin (2) is essential for its cytotoxicity, and suggests that detoxification of 2 may be carried out by biological oxidation of the indole moiety to yield 1.
Gravidity and parity in postmenopausal American Indian women: The strong heart study
Creators: name: Cowan, L.D.
name: Howard, B.V.
name: North, K.E.
name: Maccluer, J.W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: The fertility of a large sample of American Indian women participating in the Strong Heart Study was examined to determine which factors are associated with variation in completed fertility among women in this population. The Strong Heart Study (SHS) is a study of cardiovascular disease (CVD) and its risk factors in American Indians living in Arizona, Oklahoma, and the Dakotas. Data were derived from a baseline examination between 1989 and 1992 of approximately 1,500 men and women, aged 45-74, from each of the 3 SHS centers. A personal interview elicited demographic information, family health history, and information on several life-style variables. A total of 1,955 ever-married, postmenopausal women were considered in these analyses. Women were considered to be postmenopausal if their menstrual cycles had stopped completely for at least 12 months, either because of natural or surgical processes. The average number of pregnancies (gravidity) for all women was 5.9, whereas the mean number of live births (parity) was 5.3. Women living in Arizona (5.6) and the Dakotas (5.8) had higher parity than those in Oklahoma (4.6). Furthermore, there was lower completed fertility in younger women: When American Indian women from all 3 centers were considered together, women born between 1910 and 1919 had a mean parity of 5.3, whereas women born between 1940 and 1949 had a mean parity of 4.0. Although previous research has suggested a relationship between parity and CVD risk factors, no linear associations between CVD risk factors and fertility were indicated in this population. We also examined the relationship of contraception, level of education, and income to fertility. While no significant relationship between contraception and the level of fertility was identified, there was a significant inverse linear relationship of both education and income with fertility. In summary, fertility rates in American Indian women are high, but appear to be decreasing in younger generations. Fertility is higher in those with less education and lower incomes.
Genotype-by-sex interaction in the regulation of high-density lipoprotein: The Framingham Heart Study
Creators: name: Yang, Q.
name: Cupples, L.A.
name: Williams, J.T.
name: Martin, L.J.
name: Mosher, M.J.
name: North, K.E.
name: Dyer, T.D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: Low levels of high-density lipoprotein (HDL) are widely documented as a risk factor for cardiovascular disease (CVD). Furthermore, there is marked sexual dimorphism in both HDL levels and the prevalence of CVD. However, the extent to which genetic factors contribute to such dimorphism has been largely unexplored. We examined the evidence for genotype-by-sex effects on HDL in a longitudinal sample of 1,562 participants from 330 families in the Framingham Heart Study at three times points corresponding approximately to 1971-1974, 1980-1983, and 1988-1991. Using a variance component method, we conducted a genome scan of HDL at each time point in males and females, separately and combined, and tested for genotype-by-sex interaction at a quantitative trait locus (QTL) at each time point. Consistent findings were noted only for females on chromosome 2 near marker D2S1328, with adjusted LOD scores of 2.6, 2.2, and 2.1 across the three time points, respectively. In males suggestive linkage was detected on chromosome 16 near marker D16S3396 at the second time point and on chromosome 18 near marker D18S851 at the third time point (adjusted LOD = 2.2 and 2.4, respectively). Although the heritability of HDL is similar in males and females, sex appears to exert a substantial effect on the QTL-specific variance of HDL. When genotype-by-sex interactions exist and are not modeled, the power to detect linkage is reduced; thus our results may explain in part the paucity of significant linkage findings for HDL.
Antimicrobial and antioxidant phytochemicals in leaf extracts of Bergenia ligulata: a Himalayan herb of medicinal value
Creators: name: Agnihotri, Vasudha
name: Sati, Priyanka
name: Jantwal, Arvind
name: Pandey, Anita
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Plant Biology
subject: Hematology
subject: Science Policy
subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Molecular Biology
subject: Cell Biology
subject: Biochemistry

description: Phenolic and flavonoid contents in leaf extracts of Bergenialigulata have been analysed for their contribution in antimicrobial and antioxidant activities. The extracts were prepared in three solvents (separately) following maceration and soxhelt methods. The antimicrobial activity was tested using disc diffusion assay against a range of microorganisms along with the determination of minimum inhibitory concentration (MIC), while the antioxidant activity was tested following DPPH assay. Leaf extracts exhibited antimicrobial activity against all the three groups of microorganisms; results coincided with respective MIC. In general, the methanol extracts prepared through maceration favoured the determination of antimicrobial and antioxidant activities. Maximum values for phenolic and flavonoid contents were obtained in macerated methanol and ethyl acetate extracts, respectively. The statistical correlations exhibited the extent of the contribution of phenolic and flavonoid contents in antimicrobial and antioxidant activities and also indicated the involvement of other plant metabolites.
Plusiocampa (Pentachaetocampa) Sendra & Weber 2018
Creators: name: Sendra, Alberto
name: Antić, Dragan
name: Barranco, Pablo
name: Borko, Špela
name: Christian, Erhard
name: Delić, Teo
name: Fadrique, Floren
name: Faille, Arnaud
name: Galli, Loris
name: Gasparo, Fulvio
name: Georgiev, Dilian
name: Giachino, Pier Mauro
name: Kovac, L'ubomír
name: Lukić, Marko
name: Marcia, Paolo
name: Miculinić, Kazimir
name: Nicolosi, Giuseppe
name: Palero, Ferran
name: Paragamian, Kaloust
name: Pérez, Toni
name: Polak, Slavko
name: Prieto, Carlos E.
name: Turbanov, Ilya
name: Vailati, Dante
name: Reboleira, Ana Sofia P. S.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Diplura
Campodeidae
Plusiocampa

description: Subgenus Pentachaetocampa Sendra & Weber, 2018
Pentachaetocampa Sendra & Weber, 2018: 3.
Diagnosis (Sendra & Weber 2018)
Mesothoracic and metathoracic femora with five dorsal macrosetae, up to three on prothoracic femur; presence of a narrow area of glandular g 1 setae in adult females.
description: Published as part of Sendra, Alberto, Antić, Dragan, Barranco, Pablo, Borko, Špela, Christian, Erhard, Delić, Teo, Fadrique, Floren, Faille, Arnaud, Galli, Loris, Gasparo, Fulvio, Georgiev, Dilian, Giachino, Pier Mauro, Kovac, L'ubomír, Lukić, Marko, Marcia, Paolo, Miculinić, Kazimir, Nicolosi, Giuseppe, Palero, Ferran, Paragamian, Kaloust, Pérez, Toni, Polak, Slavko, Prieto, Carlos E., Turbanov, Ilya, Vailati, Dante & Reboleira, Ana Sofia P. S., 2020, Flourishing in subterranean ecosystems: Euro-Mediterranean Plusiocampinae and tachycampoids (Diplura, Campodeidae), pp. 1-138 in European Journal of Taxonomy 591 on page 24, DOI: 10.5852/ejt.2020.591, http://zenodo.org/record/3659823
Suomalaisten nikkelialtistus elintarvikkeista. Tiivistelmä kansallisen riskinarvioinnin tuloksista
Creators: name: Suomi, Johanna
Publisher: name: Zenodo
Year: 2020
Subjects: subject: nickel
subject: exposure assessment
subject: http://id.agrisemantics.org/gacs/C1470
subject: http://id.agrisemantics.org/gacs/C4343

description: This is a short document for the general reader on the dietary exposure of Finnish adults to nickel. The results summarized in this document have been presented in more detail in a national risk assessment: http://doi.org/10.5281/zenodo.3772613

description: FI; PDF; johanna.suomi@ruokavirasto.fi
The origins of the Irish Travellers and the genetic structure of Ireland
Creators: name: Crawford, M.H.
name: North, K.E.
name: Martin, L.J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: Ireland's unique and well-documented history provides insight into the formation and origins of population subdivisions. Of particular interest, is the controversial ethnogenesis of an itinerant population of Ireland: the Travellers. The objectives of this study were: (1) to determine the genetic affinity of the Travellers to the general Irish population based on gene frequency data, subdivided by county, and (2) to explore the relationship between subpopulations of Ireland, given its turbulent history. The gene frequencies of standard genetic markers collected from populations residing in counties of Ireland and the Travellers were calculated and analysed using several multivariate methods. First, a relationship (R) matrix was used to ascertain the scaled variance-covariance matrix of population similarity. Second, mean per locus heterozygosity (H) was regressed on distance of the region from the gene frequency centroid (r(ii)). The results of this study include: (1) the confirmation of Crawford's (1975, in Biosocial Interrelations in Population Adaptations, E. S. Watts et al. (eds), pp. 93-103) conclusions concerning the origins and genetic affinity of the Travellers; (2) based on several multivariate analyses, the major influence on population structure was unique historical events; and (3) Relethford and Crawford's (1995, American Journal of Physical Anthropology, 96, 25-38) hypothesis concerning the distinctiveness of the midland counties was verified by this study.
Rapid monitoring of carvacrol in plants and herbal medicines using matrix solid-phase dispersion and gas chromatography flame ionisation detector
Creators: name: Rashidipour, Marzieh
name: Rouhollah Heydari
name: Alireza Feizbakhsh
name: Payman Hashemi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Plant Biology
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Medicine
subject: Engineering

description: Matrix solid-phase dispersion (MSPD) method coupled with gas chromatography flame ionisation detector as a quick and easy extraction technique has been developed to extract carvacrol from plants and herbal medicines. Influence of important parameters on the MSPD method efficiency, such as the sorbent material, the ratio of sample to sorbent material, elution solvent and volume of the elution solvent has been evaluated and optimised. Carvacrol was successfully extracted by diatomaceous earth as sorbent with 350 μL of dichloromethane as elution solvent. The calibration curve showed good linearity (r2 = 0.9965) and precision (RSD − 1 for carvacrol. The limit of detection and limit of quantification were 0.1 and 0.5 μg mL− 1, respectively. The recoveries were in the range of 74.4–80.5% with relative standard deviation (RSD) values ranging from 8.4% to 9.8%. The reported MSPD extraction method revealed to be simpler and faster than conventional methods used to quantify carvacrol from plants and herbal medicines.
Spatial variation of anthropometric traits in Ireland
Creators: name: Relethford, J.H.
name: Crawford, M.H.
name: North, K.E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: To further elucidate the relationship between geography and genetics in Ireland, we considered variation in anthropometric traits of adult males by town using spatial autocorrelation methods. By describing and distinguishing significant patterns of anthropometric variation, we determined whether the anthropometric traits display a simple pattern of spatial variation, as predicted by the isolation by distance model, or other patterns of spatial variation. Several hypotheses were examined, including (1) whether there was spatial patterning of 20 anthropometric phenotypic distributions and 7 principal components of Irish males and (2) if there was, whether these phenotypic distributions could be explained by a simple isolation by distance model. The results of this study can be summarized by several key findings: (1) There is significant spatial patterning among towns, as detected in correlograms of 14 anthropometric traits and 2 principal component factor scores (values of Moran's I ranging from 0.7510 to -0.3616, p ≤ 0.0071); (2) 4 spatial patterns were detected, including clinal patterns, long-distance differentiation, distance distinction, and regional patchiness. These results suggest several likely causes of the observed spatial patterns. First, in Ireland patterns of anthropometric variation could not be explained by a single spatial pattern (i.e., isolation by distance). Second, through an examination of the various combinations of statistical homogeneity or heterogeneity, spatial patterning or nonpatterning, and similarity or dissimilarity of spatial patterns, we conclude that several migrational events structured the genetic landscape of Ireland.
La figura del Community Manager: voz de la marca en las redes sociales
Creators: name: Chez Abreu, Claudia
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 350604
subject: Marketing communications
classificationCode: 350612
subject: Social marketing

description: Este artículo aborda el rol emergente del Community Manager dentro de la gestión de marca en las plataformas de redes sociales. A través de una exploración detallada, Claudia Chez Abreu presenta los roles y responsabilidades multifacéticas asociadas a esta posición, subrayando la evolución de las tareas desde un enfoque unipersonal en marcas pequeñas a la necesidad de un equipo más amplio y estratégico para marcas en crecimiento. Referenciando a expertos en la materia como Connie Bensen y Jeremiah Owyang, el artículo destaca la importancia del monitoreo continuo, la promoción de relaciones con los consumidores, la generación de conversación alrededor de eventos y productos, y la identificación de retroalimentación para la mejora de productos y servicios. Además, enfatiza la capacidad estratégica necesaria para el Community Manager, más allá de la creación de contenidos, como un elemento crucial para su desarrollo profesional y el éxito en la gestión de comunidades online.
Candida dubliniensis in Japanese Oral Microbiota: A Cross-Sectional Study of Six Geographic Regions in Japan
Creators: name: Komabayashi, Takashi
name: Ahn, Chul
name: Ohshima, Keijiro
name: Meyer, Karen
name: Ohshima, Tomoko
name: Mukai, Yoko
name: Watanabe, Hitoshi
name: Maeda, Nobuko
name: Makimura, Koichi
Publisher: name: MDPI
Year: 2024

description: Introduction: Candida dubliniensis was reclassified from the C. albicans genotype D, and
reports show its frequent detection in HIV-positive individuals and easy acquisition of antifungal
drug resistance. However, the oral carriage rate in healthy people and contribution to candidiasis
in Japan is unclear. Methods: We conducted a cross-sectional survey of the C. dubliniensis carriage
rate, performed genotyping and tested antifungal drug susceptibility and protease productivity.
Specimens from 2432 Japanese subjects in six regions (1902 healthy individuals, 423 with candidiasis
individuals, 107 HIV-positive individuals) were cultured using CHROMagarTMCandida, and the
species was confirmed via 25S rDNA amplification and ITS sequences analyzed for genotyping.
Results: The C. dubliniensis carriage rate in healthy Japanese was low in the central mainland (0–15%)
but high in the most northerly and southerly areas (30–40%). The distribution of these frequencies
did not differ depending on age or disease (HIV-infection, candidiasis). Genotype I, previously
identified in other countries, was most frequent in Japan, but novel genotypes were also observed.
Six antifungal drugs showed higher susceptibility against C. albicans, but protease productivity was
low. Conclusions: Oral C. dubliniensis has low pathogenicity with distribution properties attributed
to geography and not dependent on age or disease status.
Designing competitive industry sectors
Creators: name: Peppou, G.
name: Bucolo, Sam
name: Thurgood, Clementine
Publisher: name: Swinburne
Year: 2024

description: Industry sectors are typified by their complex, networked and open nature; characteristics making them well suited to innovation through the application of design. In spite of this apparent suitability there remains little research published specifically regarding the application of design to sector-level strategy formation. In response to this apparent suitability of design, a Design-Led Innovation (DLI) (Bucolo, 2016) approach was modified to scale to a sector. DLI is a design thinking method that integrates deep customer insights into business models informing organisational transformation and strategy. This paper explores the adaptations and challenges that occur when scaling design to a sector in the form of a proposed framework: The Sector Grand Challenge Framework (SGC Framework). This is described through a case study applying the SGC Framework to the development of a Food and Agribusiness (Agrifood) growth and competitiveness strategy in partnership with Food Innovation Australia Limited (FIAL), an Australian Federal Government Industry Growth Centres initiative. The SGC Framework uses many of the same principles as DLI, scaling from successful applications to small and large firms to an entire industry sector. This scale exacerbates key challenges observed within a firm including: poor linkages between groups, large, complex stakeholder networks, and lack of unifying purpose or vision. Based on this initial experience there is a significant opportunity for future research both into the new value created by a Design-Led approach to sector level challenges and the implications for design as a field.
The impact of currency unions on trade: lessons from CFA franc zone and implications for proposed African monetary unions
Creators: name: BANGAKE, CHRYSOST
name: EGGOH, JUDE
Publisher: name: Universit� degli studi di Bergamo
Year: 2009

description: In this paper we explore whether the two existing currency unions in CFA Franc zone have a significant increase in trade between members. Furthermore, the impact of regional agreements which are only based on preferential trade (ECOWAS, COMESA, and SADC) is also analysed. Using panel techniques for 35 countries in Africa on the period 1980-2005, our empirical results strongly support that existing currency unions in CFA zone enhance significantly the trade between members. However, the Rose effect is more substantial in UEMOA than in CEMAC. Our results show that during their implementation the regional agreements which are only based on preferential trade (ECOWAS for example) have generated a little increase in trade compared to countries in currency unions. These results are highly interesting and have some policy implications for the proposed monetary unions in Africa.
title: Kin and knowledge
title: the meaning and acquisition of Indigenous ecological knowledge in the lives of young Aboriginal people in Central Australia
titleType: Subtitle
Creators: name: Douglas, Josephine Claudia
Publisher: name: Charles Darwin University
Year: 2015

description: This is an ethnographic study about young Aboriginal people in Central Australia. The voices and opinions of more than 150 Aboriginal youth were analysed. My findings show that Indigenous Ecological Knowledge (IEK) is an active part of their lives. This knowledge and practice contributes to the identity and pride of youth from Central Australia. Young Aboriginal people are commonly portrayed in the media as problems. Negative stereotypes and deficit narratives imply they occupy a failed space within and between Aboriginal and non-Aboriginal worlds. Youth are said to be lacking in culture and disinterested in cultural practices. My findings contradict such stereotypes and deficiencies. The lived experiences of Aboriginal people are often invisible to mainstream Australian society. Rarely do we hear from young Aboriginal people themselves. Their role as players in a system of knowledge is simultaneously ignored and assumed. IEK is characterised as the domain of the older generation but not younger generations. This thesis goes beyond academic attention to IEK in environmental programs, developmental theories or the nexus between Indigenous and Western or scientific knowledge. The study explores the social lives of young Aboriginal adults. Mixed methods were used to examine the learning practices, learning contexts and cultural acquisition processes that underpin IEK. Qualitative results from interviews, surveys and observations are presented. I look at how IEK is made to happen, how knowledge and practice is realised in contemporary contexts. The study shows that people’s everyday lived experience integrates IEK. Cultural knowledge is vulnerable to the stresses and forces of modern life; yet it persists. Factors that enable IEK to persevere are examined. I have found that hunting, bush food and medicine harvesting, and natural resource use contribute to IEK. Practices and beliefs are enriched through ceremonial life, health and healing, and in observances in bereavement and funerals. Amongst younger people there is an ongoing belief in the sentience of country. This research revealed that IEK is a vital part of youth values and beliefs. Beliefs inform youth practice. IEK is expressed through relationship to families and people’s connections to each other. Young people demonstrate their care for older and younger generations through the collection, preparation and use of natural resources. ‘Relatedness’ continues to be the currency of knowledge transmission. Feelings of love, duty and care motivate young people to listen, learn and do things for their older and younger loved ones. Deep and powerful feelings for family members call young people to action. Young people are integral to the future of Indigenous Ecological Knowledge and practice in Central Australia.
Plusiocampa (Pentachaetocampa) inopinata Sendra & Weber 2018
Creators: name: Sendra, Alberto
name: Antić, Dragan
name: Barranco, Pablo
name: Borko, Špela
name: Christian, Erhard
name: Delić, Teo
name: Fadrique, Floren
name: Faille, Arnaud
name: Galli, Loris
name: Gasparo, Fulvio
name: Georgiev, Dilian
name: Giachino, Pier Mauro
name: Kovac, L'ubomír
name: Lukić, Marko
name: Marcia, Paolo
name: Miculinić, Kazimir
name: Nicolosi, Giuseppe
name: Palero, Ferran
name: Paragamian, Kaloust
name: Pérez, Toni
name: Polak, Slavko
name: Prieto, Carlos E.
name: Turbanov, Ilya
name: Vailati, Dante
name: Reboleira, Ana Sofia P. S.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Diplura
Campodeidae
Plusiocampa
Plusiocampa inopinata

description: Plusiocampa (Pentachaetocampa) inopinata Sendra & Weber, 2018
Plusiocampa (Pentachaetocampa) inopinata Sendra & Weber, 2018: 5, figs 1–17, table 1.
Diagnosis (Sendra & Weber 2018)
Troglomorphic species. Sparse thin and long clothing notal setae with thin barbs. Antennae in adults with 32–33 antennomeres. Cupuliform organ with 12–14 complex olfactory chemoreceptors. Frontal process developed, with slightly tubercular setae and macrosetae. Pronotum with 1+1 ma, 4+4 la, 2+2 lp macrosetae; mesonotum with 1+1 ma, 3+3 la, 2+2 lp, 1+1 mp macrosetae; metanotum with 1+1 ma, 1+1 la, 2+2 lp, 1+1 mp macrosetae; long, thin macrosetae, with very thin barbs; subequal to slightly unequal claws (posterior claw 1.05–1.15) with large lateral crests; posterior claw with backward overhang; pretarsal lateral process long, smooth and setiform with several short proximal barbs. Urotergites I–II with 1+1 post 1 macrosetae; urotergite III with 1+1 la, 1+1 post macrosetae; urotergite IV with 1+1 la, 2+2 (3+2, 3+3) post macrosetae; urotergites V–VII with 1+1 la, 5+5 post macrosetae; urotergite VIII with 6+6 (5+6, 5+5) post macrosetae; abdominal segment IX with 8+8 (8+7) post macrosetae. Urosternite I with 7+7 (7+6), urosternites II–VII with 5+5, urosternite VIII with 2+2 macrosetae. Male with a narrow area with glandular g 1 setae, enlarged subcylindrical appendages with glandular a 1 setae; female with glandular g 1 setae with subcylindrical appendages, thinner than in male.
Habitat and distribution
Monotypic subgenus known only from a single cave in southwest Germany (Fig. 211).
description: Published as part of Sendra, Alberto, Antić, Dragan, Barranco, Pablo, Borko, Špela, Christian, Erhard, Delić, Teo, Fadrique, Floren, Faille, Arnaud, Galli, Loris, Gasparo, Fulvio, Georgiev, Dilian, Giachino, Pier Mauro, Kovac, L'ubomír, Lukić, Marko, Marcia, Paolo, Miculinić, Kazimir, Nicolosi, Giuseppe, Palero, Ferran, Paragamian, Kaloust, Pérez, Toni, Polak, Slavko, Prieto, Carlos E., Turbanov, Ilya, Vailati, Dante & Reboleira, Ana Sofia P. S., 2020, Flourishing in subterranean ecosystems: Euro-Mediterranean Plusiocampinae and tachycampoids (Diplura, Campodeidae), pp. 1-138 in European Journal of Taxonomy 591 on page 24, DOI: 10.5852/ejt.2020.591, http://zenodo.org/record/3659823
Microfinance and poverty reduction in rural Nigeria
Creators: name: AIDEYAN, OSAORE
Publisher: name: Universit� degli studi di Bergamo
Year: 2009

description: There is extensive experience in microfinance provision in Africa, but relatively few empirical studies on the social and economic benefits to clients. This paper draws on original surveys of 281 rural households in Southern Nigeria, some of which are served by two microfinance programs but have not received any loans. The statistical tests show that households with access to programs do have more substantial social and economic benefits than those without access. The evaluation holds important lessons for studies on other programs in many African countries.
The impact of Asian financial crisis on bank performance: empirical evidence from Thailand and Malaysia
Creators: name: SUFIAN, FADZLAN
name: HABIBULLAH, MUZAFAR SHAH
Publisher: name: Universit� degli studi di Bergamo
Year: 2009

description: By using bank level data this paper examines how bank specific characteristics and the macroeconomic environment affects the profitability of the Thailand and Malaysian banking sectors over the period 1992-2003. All the variables are significant although their impact is not always the same for Thailand and Malaysian banks. We find that liquidity is negatively related to Thailand banks? profitability, but not in Malaysia, while network embeddedness has negative relationship with Malaysian banks, but not Thailand banks. As for the impact of macroeconomic indicators, we find that economic growth is positively related to Thailand banks? profitability only during the pre-crisis period. The impact of inflation is positive on Thailand banks? profitability during the crisis and post-crisis periods, while inflation is negatively related to Malaysian banks? profitability during the crisis period. We find that the Thailand banking sector has been relatively more profitable during the pre-crisis period, while the opposite is true for the Malaysian banking sector.
Cytotoxic constituents of Abutilon indicum leaves against U87MG human glioblastoma cells
Creators: name: Rukaiyya Sirajuddin Khan
name: Mahibalan Senthi
name: Poorna Chandra Rao
name: Basha, Ameer
name: Alvala, Mallika
name: Tummuri, Dinesh
name: Masubuti, Hironori
name: Fujimoto, Yoshinori
name: Ahil Sajeli Begum
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: Science Policy
subject: Cancer
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Cell Biology
subject: Biochemistry

description: The study was aimed to identify cytotoxic leads from Abutilon indicum leaves for treating glioblastoma. The petroleum ether extract, methanol extract (AIM), chloroform and ethyl acetate sub-fractions (AIM-C and AIM-E, respectively) prepared from AIM were tested for cytotoxicity on U87MG human glioblastoma cells using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. These extracts exhibited considerable activity (IC50 values of 42.6–64.5 μg/mL). The most active AIM-C fraction was repeatedly chromatographed to yield four known compounds, methyl trans-p-coumarate (1), methyl caffeate (2), syringic acid (3) and pinellic acid (4). Cell viability assay of 1–4 against U87MG cells indicated 2 as most active (IC50 value of 8.2 μg/mL), whereas the other three compounds were much less active. Interestingly, compounds 1–4 were non-toxic towards normal human cells (HEK-293). The content of 2 in AIM-C was estimated as 3% by HPLC. Hence, presence of some more active substances besides methyl caffeate (2) in AIM-C is anticipated.
Το αισθητικό στοιχείο στο νερό, τα υδραυλικά έργα και τα φράγματα
Creators: name: Sargentis, G.-Fivos
Publisher: name: Zenodo
Year: 1998

description: Το αισθητικό στοιχείο στο νερό, τα υδραυλικά έργα και τα φράγματα. Διπλωματική εργασία στην Σχολή Πολιτικών Μηχανικών Ε.Μ.Π.
CESSDA SaW D5.1: Benchmarking report, including an action plan for improvements on an inter - consortium and individual archive level
Creators: name: Alfredsson, Iris
name: Jerlehag, Birger
name: Lace, Ilse
name: Ilijasic Versic, Ivana
Publisher: name: Zenodo
Year: 2017
Subjects: Strategy and Policy
Curation and Preservation

description: The aim of D5.1 is to benchmark, using a set of indicators produced in D3.1 and serving as the basis for a comparison between CESSDA and an “industry best” or “gold standard” organisation. The Inter-university Consortium for Political and Social Research (ICPSR) is taken as the gold standard and has been used as a benchmark organisation for CESSDA. D5.1 contains analysis of differences and a breakdown of actions that should be taken to bring CESSDA up to the level of the gold standard.