cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Global analysis of the biosynthetic chemical space of marine prokaryotes
Creators: name: Wei, Bin
name: Hu, Gang-Ao
name: Zhou, Zhen-Yi
name: Yu, Wen-Chao
name: Du, Ao-Qi
name: Yang, Cai-Ling
name: Yu, Yan-Lei
name: Chen, Jian-Wei
name: Zhang, Hua-Wei
name: Wu, Qihao
name: Xuan, Qi
name: Xu, Xue-Wei
name: Wang, Hong
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Organic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1: Figure S1. Flowchart for the collection of marine prokaryotic genomes. Figure S2. (A) BGC counts, (B) ratio of BGCs on edge, and (C) number of genomes in genomes with varying degrees of completeness. Figure S3. Bar chart depicting the composition of GCFs within genomes of different categories, (A) all taxa, (B) bacteria, (C) archaea, (D) cultured genome, (E) MAG, and (F) SAG. Figure S4. A selected (A) RiPPs and (B) NRPS gene cluster family (GCF) and the comparison of the BGCs in the corresponding GCF. Figure S5. The predicted core peptides of BGCs in selected RiPPs GCFs. The peptide sequences from each GCF were aligned using Muscle [2] and then visualized in TBtools [3]. Figure S6. Gene cluster family network of the 25 predicted BGCs from Aquimarina muelleri DSM 19832 T. A. muelleri DSM 19832 T possesses 20 orphan BGCs and five genus-specific BGCs (only showing a high similarity to BGCs from Aquimarina strains). Figure S7. Comparison of the experimental mass spectrum of N-acetyltryptamine with its spectrum from the GNPS database. Figure S8. Genomic distribution of secondary metabolite biosynthetic genes clusters in A. muelleri DSM 19832 T. The biosynthetic gene clusters are shown in the outer layer. Table S1. Genomic features and the anti-SMASH results of the 33,904 marine prokaryotes-derived genomes. Table S2. Information about the 70,011 BGCs. Table S3. Information about the reported microbial natural products. Table S4. Information about the 24,536 GCFs. Table S5. Information about the RiPPs BGCs. Table S6. Information about the core peptides encoded by RiPPs BGCs. Table S7. Metabolite annotation in metabolomic data of A. muelleri DSM 19832 T.
Integral Picard group of moduli of polarized K3 surfaces
Creators: name: Di Lorenzo, Andrea
name: Fringuelli, Roberto
name: Vistoli, Angelo
Publisher: name: Humboldt-Universität zu Berlin
Year: 2023
Subjects: subject: 14C22
subject: 14D23
subject: 14J28: K3 surfaces and Enriques surfaces
subject: 510 Mathematik

description: We compute the integral Picard group of the moduli stack of polarized K3 surfaces of fixed degree whose singularities are at most rational double points, and of its coarse moduli space. We also compute the integral Picard group of the stack of quasi‐polarized K3 surfaces, and of the stacky period domain.
Horse mussel reef ecosystem services: evidence for a whelk nursery habitat supporting a shellfishery
Creators: name: Kent, Flora E. A.
name: Gray, Mark J.
name: Last, Kim S.
name: Sanderson, William G.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Demonstrating the benefits that marine ecosystems provide to society can support marine spatial planning and enhance the protection of fragile, biodiverse habitats. However, the importance of ecosystem services provided by such habitats is rarely accounted for in spatial management due to a lack of detailed information. The present study investigated the ‘habitat provision’ ecosystem service delivered by horse mussel (Modiolus modiolus (L.)) reefs, a ‘Priority Marine Habitat’ in the NE Atlantic. By working with local fishers, the abundance and demographics of commercially important whelks (Buccinum undatum) were examined. B. undatum catches were three times higher on reef sites and a greater number of smaller individuals were caught on the reefs compared to off-reef habitats. We therefore show that these productive and physically complex mussel reefs are important feeding and nursery areas for whelks, demonstrating the ‘essential fish habitat’ value of the now rare M. modiolus reefs. The results are discussed in the context of marine spatial planning and the potential for historically more widespread shellfish habitats to have been capable of providing substantial ecosystem services.
Proposed Modification of the 8th Edition of the AJCC Staging System for Gastric Cancer
Creators: name: Jiang, Yannan
name: Tu, Ruhong
name: Lu, Jun
name: Zhang, Yan
name: Zhu, Jianhua
name: Tang, Wei
name: Gu, Menghui
name: Huang, Changming
name: Gu, Xinhua
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Background: The American Joint Committee on Cancer (AJCC) staging system has been the standardized staging system for malignancies since the first edition in 1987. The 8th edition of gastric cancer was released in 2016, and is expected to be used in clinical practice in 2018. The aim of this study was to improve this new gastric cancer staging system. Methods: We conducted median overall survival analyses in a cohort of 8359 gastric cancer patients from the Surveillance, Epidemiology, and End Results (SEER) database (2004–2014) via Kaplan–Meier curves and log-rank tests, and proposed a modified staging system based on median OS. The concordance index (C-index) was conducted to evaluate the predictive accuracy. Results: Using the 8th AJCC staging system, the median OS of patients at the same stage varied widely between the different substages, especially in stage III. Despite the definitions of T, N, and M, substages in the modified staging system were regrouped based on median OS. The C-index of stage III patients with the modified staging system [0.579, 95% confidence interval (CI) 0.564–0.593] was higher than the 8th AJCC staging system (0.567, 95% CI 0.552–0.581). Moreover, we divided these patients into two groups according to their examined lymph node counts (≥15 or 1–14), and studied the effectiveness of the modified staging system in the two groups. Conclusions: The modified 8th AJCC staging system for gastric cancer proposed in this study generates better prognostic stratifications and may be evaluated for further update.
Abbreviations:AJCCAmerican Joint Committee on CancerOSOverall SurvivalSEERSurveillance, Epidemiology, and End Results
 American Joint Committee on Cancer Overall Survival Surveillance, Epidemiology, and End Results
title: Identification and diversity of mixed strain infections of mycobacterium avium subspecies paratuberculosis in dairy cattle from Canadian herds
Creators: name: Byrne, Alexander Stephen
Publisher: name: Memorial University of Newfoundland
publisherIdentifier: https://ror.org/04haebc03
publisherIdentifierScheme: ROR
Year: 2024

description: Mycobacterium avium subsp. paratuberculosis (MAP) is the pathogen responsible for Johne’s Disease (JD) in ruminants, a cause of substantial economic loss in the global dairy industry. JD is a major problem in dairy animals, and concerns have been raised regarding the association of MAP with Crohn’s Disease in humans. Mixed strain infections (MSI) refer to the concurrent infection of a susceptible host with multiple strains of a single pathogenic species. Microevolution refers to within-host changes in an infecting strain which lead to genetically distinguishable progeny. Both processes influence host-pathogen dynamics and disease progression, but not much is known about their prevalence and impact on JD. In this thesis we first conducted a systematic review on how MSIs are defined in the literature, how widespread the phenomenon is among host species and how MSIs are detected. Next, we characterized MAP isolates from 67 cows using whole genome sequencing (WGS) based methods. SNP-based analysis of WGS data, when combined with animal movement data, was able to document disease transmission between herds. Finally, up to 10 MAP isolates from 14 high-shedding animals were examined using WGS to identify the prevalence of MSIs and microevolution. Two animals showed evidence of microevolution, while the remaining twelve showed evidence of both microevolution and MSIs. Our results showed a need for further investigation of MSIs within animal-based infections, that examination of short sequence repeats allows for greater discrimination between strains, and that differences in these repeats significantly alter protein structure.
The Influence of Stock Assessment Frequency on the Achievement of Fishery Management Objectives
Creators: name: Li, Yang
name: Bence, James R.
name: Brenden, Travis O.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Because of resource limitations with respect to both funding and staff expertise, there is growing interest among fishery management agencies in moving from annual to less-frequent assessments of fish stocks. We conducted simulations based on Lake Whitefish Coregonus clupeaformis populations in the Laurentian Great Lakes to evaluate (1) how statistical catch-at-age assessment frequency, the time lag between data collection and assessment, and approaches to setting target harvests in the years between assessments affected the achievement of management objectives; and (2) how the outcomes were influenced by the quality of assessment data, features of the populations, and characteristics of the fisheries exploiting the populations. We found that as assessments became less frequent, relative yields were reduced and the risk of stock depletion and interannual variation in yield increased. The effects of less-frequent assessments were ameliorated in populations with greater levels of productivity and when target mortality was lower. Conversely, the effects of assessment frequency were largely insensitive to changes in recruitment variation or the quality of assessment data. A 1-year lag between data collection and assessment when assessments were conducted annually primarily affected the risk of stock depletion and the interannual variation in yield. As recruitment variation increased, relative yield also became sensitive to the 1-year lag. Approaches to setting harvest targets in years between full assessments were less important than assessment frequency, and no single approach consistently outperformed other rules. Although populations with low productivity were the most sensitive to changes in assessment frequency and the lag between data collection and assessment, the management of those populations benefited to a greater extent from implementation of an appropriate target mortality rate than from more-frequent assessments or removal of the 1-year lag. Received November 18, 2015; accepted March 9, 2016 Published online July 7, 2016
Additional file 2 of MiR-196b-3p and miR-450b-3p are key regulators of adipogenesis in porcine intramuscular and subcutaneous adipocytes
Creators: name: Wu, Wenjing
name: Liu, Keke
name: You, Zhongyu
name: Zhang, Jin
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Virology
subject: Computational Biology

description: Supplementary Material 2
Additional file 3 of MiR-196b-3p and miR-450b-3p are key regulators of adipogenesis in porcine intramuscular and subcutaneous adipocytes
Creators: name: Wu, Wenjing
name: Liu, Keke
name: You, Zhongyu
name: Zhang, Jin
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Virology
subject: Computational Biology

description: Supplementary Material 3
The Proliferation of Gated Communities in Ghana: A New Institutionalism Perspective
Creators: name: Ehwi, Richmond Juvenile
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Gated communities
Land administration
land use planning
Greater Accra Metropolitan Area
Inner-city
Middle-core
Peri-urban
serviced-plot-gated-communities
hybrid gated communities
master-planned-and-built gated communities

description: From the late 1980s, debates regarding the proliferation of gated communities have progressed from being US-centric to acknowledgement of an international research agenda. Despite their ubiquity globally, there is a dearth of empirical research about how developers of gated communities navigate the processes heralding the commencement of their projects. Previous studies have focused upon the mutually beneficial relationship between developers and fiscally distressed local government authorities. Such studies also reflect exigencies in contexts with privatised land markets, and local planning authorities wield unfettered control over urban planning and residential development. However, in Ghana, where gated communities are rapidly proliferating, the land administration and land-use planning systems are problematic. Hence this research examines how the land administration and landuse planning systems in Ghana have contributed to the proliferation of gated communities following experiences from key actors involved in the development process and residents who move into gated communities. Drawing upon new institutionalism and using a mixed research method, the research presents the case of the Greater Accra Metropolitan Area. It finds that the institutional landscape in Ghana's built environment creates both direct and indirect incentives that benefit developers. Also, the challenges in land administration and land-use planning shape how developers understand gated communities, the typology found in Ghana, and the features that characterize them. Additionally, developers’ engagement with other key actors in the development process reinforces 'practical norms' in the land acquisition, land title registration, and building permit acquisition in Ghana. Finally, the research confirms the hypothesis that land administration challenges in Ghana significantly contribute to why people move into gated communities. Also, residents' demographic and locational characteristics emerged as significant predictors of their likelihood to move into gated communities due to land administration challenges. The research also reflects on implications for theory, future research and policy.
description: Cambridge Africa Scholarship (Cambridge Trust)
Additional file 1 of MiR-196b-3p and miR-450b-3p are key regulators of adipogenesis in porcine intramuscular and subcutaneous adipocytes
Creators: name: Wu, Wenjing
name: Liu, Keke
name: You, Zhongyu
name: Zhang, Jin
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Virology
subject: Computational Biology

description: Supplementary Material 1
Chemoselective synthesis and spectral studies of N-thiocyanatoacetyl derivatives of 3-alkyl-2,6-diarylpiperidin-4-ones
Creators: name: M. Velayutham Pillai
name: K. Rajeswari
name: C. Udhaya Kumar
name: C. Ramalingan
name: A. Manohar
name: T. Vidhyasagar
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences

description: A series of N–thiocyanatoacetyl derivatives of 3–alkyl–2,6–diarylpiperidin–4–ones has been synthesized by the reaction between the N–chloroacetyl derivatives of the respective piperidin–4–ones and the ambident thiocyanate nucleophile. The synthesized compounds have been characterized through FT–IR, 1H, 13C, 1H–1H COSY, 1H–13C COSY and NOESY spectra. The spectral data reveal the conformational priority of the six-membered heterocyclic ring.
Fitting Interatomic Potentials to Reproduce Phase Transitions
Creators: name: Schlegel, Martin
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: interatomic potentials
phase diagrams
phase transitions
copper
gold
titanium
nested sampling
Nelder-Mead method
fitting interatomic potentials
CuAu
Ti
melting curve
eutectic

description: Due to the high computational demand of quantum mechanical simulations, researchers still rely on models for atomic interactions to simulate a large number of atoms. These so called “interatomic potentials” take a variety of forms ranging from the simple Lennard-Jones potential to machine learning potentials. They are usually fitted for specific structures as well as pressure and temperature realms and do not necessarily reproduce the full experimentally known solid and liquid phase diagram. There have been limited trials of fitting the parameters of interatomic potentials to phase transitions. In this work, I present improvements upon two already existing potentials from the literature – a CuAu potential and a Ti potential. These potentials are modified so that they reproduce experimental phase transitions better than before. For the CuAu potential, I fit the eutectic melting curve using my own implementation of the Nelder-Mead algorithm. The Ti potential is modified to predict a triple point which is in qualitative agreement with experimental predictions. To calculate phase transitions, I use the nested sampling algorithm which was already established in the literature. The Ti nested sampling results are verified with thermodynamic integration. My Nelder-Mead implementation allows for semi-automatic submission and analysis of the nested sampling runs. Both potentials are improved considerably. The new CuAu potential now accurately reproduces the melting curve for the alloy compositions used in the fitting procedure. The new Ti potential now – as opposed to before the modifications – predicts a triple point which is in qualitative accordance with experimental predictions. My work demonstrates how the transferability of potentials can be improved by just slight modifications to the original parameters using experimental data of the phase diagram. The Nelder-Mead implementation used for the CuAu potential could be used to improve other potentials. To fit more complex systems, the way the objective function is calculated could be upgraded in future.
description: EPSRC Centre for Doctoral Training in Computational Methods for Materials Science under grant number EP/L015552/1. Computing time on the ARCHER UK National Supercomputing Service (http://www.archer.ac.uk) via the UKCP consortium funded by EPSRC grants ref EP/K013564/1 and ref EP/P022561/1. Additional funding from King's College (Cambridge) after the third year of the PhD.
Römische Mitteilungen, Vol. 130 (2024)
Creators: name: Römische Mitteilungen
Publisher: name: Römische Mitteilungen
Year: 2025

description:   
description: Nachwort zur Wiedereröffnung des Institutsgebäudes in der Via Sardegna
Creta a Praeneste. Teseo e Arianna nel mosaico dei Pesci
Il Palatino tra il XVIII e il XIX secolo
“Era stata trovata nello scassare fra certe anticaglie una lapide sepolcrale di marmo con iscrizione”
Zur Herkunft der Inschrift ICUR 3900
New Insights into the Building Design and Construction Phases of the Constantinian Bishop’s Church at Ostia
The mid-Republican Temples at Largo Argentina in Rome
Un ritratto di Commodo nelle collezioni del Castello del Buonconsiglio (Trento)
Livias Bauten in Rom
I pozzetti rituali sul fronte della Basilica Iulia e la riscoperta dei cd. calicetti di Giacomo Boni
La Basilica Aemilia e il lato settentrionale del Foro Romano dalla media repubblica al primo impero
Die gemusterten Glasperlen und Anhänger Verucchios (Emilia-Romagna, Italien) des 8.-7. Jhs. v. Chr.
Second mora phenomena in Central and Northern dialects of Finnish
Creators: name: Karlin, Robin
Publisher: name: Zenodo
Year: 2016

description: Finnish is a Finno-Ugric language spoken by approximately 5 million native speakers, the great majority of whom live in Finland. The linguistic situation in Finland is somewhat unique; in addition to regional dialects, there are standard forms of the language that are in wide use despite not truly being the native language of any Finnish speakers. Notably, kirjakieli (‘book language’), the written standard, is taught in schools throughout Finland, and used in contexts such as the news, political speeches, and written prose; additionally, standard puhekieli (‘speech language’) is used in popular television shows and films, as well as when two interlocutors are not from the same dialect region. However, the regional dialects of Finnish are still vigorous. Children acquiring Finnish first learn their regional dialects, and only learn the standard forms in school and through exposure to Finnish media. Despite formal teaching and exposure to standard forms of the language, even “standard” puhekieli is often colored by features from the speaker’s regional dialect. To date, most papers that focus on Finnish in generative linguistics deal with some type of standard Finnish: either kirjakieli or puhekieli, which approximates the Hame dialects, spoken in and ¨ around the urban centers of Helsinki and Tampere. In this paper, I will be focusing on second-mora lengthening (SML), a phonological phenomenon present in two major dialect groups of Finnish: Savo dialects, spoken in central-eastern Finland, and Pohjanmaa dialects, spoken in central-western Finland. I argue, in contrast with previous proposals, that SML in Finnish is not simply a phonetic lengthening due to the presence of an intonational contour, but rather that it reflects an initial moraic foot with some domain-final process of extension. The rest of this paper is organized as follows: in Sec. 2, I will provide a description of SML in both Finnish and other Finnic languages. In Sec. 3 I will discuss previous proposals and argue that an alternative analysis is necessary, which I will elaborate on
description: This thesis is copyrighted, and is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) - see https://creativecommons.org/licenses/by-nc-nd/4.0/
First synthesis of a new fullerene oximes bis(9-[hydroxo]-1-[1′-hydroxymino-2′-oxo-2′-alkyl-ethyl])1,9-dihydro-[C60-Ih][5,6]fullerenes via reaction of C60 with ketones and NaNO2 promoted by HCl
Creators: name: Bulgakov, Ramil G.
name: Kinzyabaeva, Zemfira S.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: A mixture of cis-2 and cis-3 isomers of new fullerene derivatives bis(9-[hydroxo]-1-[1′-hydroxymino-2′-oxo-2′-alkyl-ethyl])-1,9-dihydro-[C60-Ih][5,6]fullerenes have been selectively synthesized with high yields at the reaction of C60 fullerene with ketones Me2CO, EtMeCO, i-PrMeCO, PhMeCO in the presence of NaNO2 and HCl.
title: 01_2817
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
iSALE-Dellen manual
Creators: name: Collins, Gareth S.
name: Elbeshausen, Dirk
name: Davison, Thomas M.
name: Wünnemann, Kai
name: Ivanov, Boris
name: H. Jay Melosh
Publisher: name: figshare
Year: 2016
Subjects: subject: Planetary Science
subject: Planetary Geology
subject: 80110 Simulation and Modelling
subject: FOS: Computer and information sciences
subject: Solid Earth Sciences
subject: Computer Software
subject: Computational Physics

description: Manual for the Dellen release of the iSALE shock physics code: A multi-material, multi-rheology shock physics code for simulating impact phenomena in two and three dimensions.
Additional file 1 of A novel nomogram based on cell cycle-related genes for predicting overall survival in early-onset colorectal cancer
Creators: name: Xiang, Meijuan
name: Gao, Yuan
name: Zhou, Yue
name: Wang, Muqing
name: Yao, Xueqing
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Additional file 1: Supplementary Figure 1. (A)HALLMARK and GO analysis of GSEA indentified cell cycle-associated genesets as the most enriched oncological signature of EOCRC cohort in GSE 41258 comparedwith the normal  cohort. (B,C) Before(B) and after(C) batchprocessing of GEO sets. (D) GSVAanalysis indicating downregulation of 9 pathway in high-risk group compare withlow-risk group based on GO set. (E)Normal and colorectal cancer samples could be distinguish definitely by PCAanalysis accroding to the 4 cell cycle- related hub genes. Abbreviations: NES, normalized enrichment score; FDR, false discovery rate; PCA, principal component analysis; READ, rectal cancer;COAD, colon cancer; GSEA, Gene set variation analysisand gene set enrichment analysis; GSVA, Gene Set VariationAnalysis; EOCRC, early-onset colorectal cancer. Supplementary Table 1. Baselinecharacteristics of early-onset colorectal cancer. patients in the GEO and TCGAcohorts. Abbreviations: GEO, GeneExpression Omnibus database; TCGA, The Cancer Genome Atlas  database. Supplementary Table 2. 98 commondifferentially expressed cell-cycle genes of early-onset colorectal cancer. Supplementary Table 3. Unicox genes of early-onset colorectal cancer. Supplementary Table 4. The sequences  of  qPCR primers.
Synthesis, structures, luminescent and dielectric properties of lanthanide coordination polymers
Creators: name: Cao, Xing-Xing
name: Li-Zhuang Chen
name: Pan, Qi-Jian
name: Huang, Yao
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Marine Biology

description: Under hydrothermal conditions, four lanthanide coordination polymers were synthesized based on 4-(4,5-dicarboxy-1H-imidazol-2-yl)pyridine 1-oxide (H3DCImPyO), with the molecular forumulas [Eu(HDCImPyO)·(H2O)2·(CHO2)]n (1), [Sm(HDCImPyO)·(H2O)2·(HCO2)]n (2), {[La(HDCImPyO)·(H2O)·(HCO2)]·O2}n (3) and {[Y(HDCImPyO)·(C2O4)·(H2O)2]·H2O}n (4). With diverse coordination modes, they were further characterized by elemental analysis, infrared spectroscopy, dielectric measurement, and single-crystal X-ray structural analysis. Complexes 1 and 2 were isostructural and had similar structures with {44, 62} topology. Complex 1 exhibited strong fluorescent emission in the solid state at room temperature. In 3, HDCImPyO2− adopted μ4-kO, O′: kO′, O′′: O′′′: O′′′′ coordination to bridge four La(III) ions to form a 3-D framework with {4. 52}2{42. 510. 612. 7. 83} topology. In 4, both HDCImPyO2− ligands and Y3+ cations were simplified as linkers to form an interpenetrating 3-D framework with {413. 62}2{422. 66} topology.
What Migrants Want
Creators: name: Staley, Frank M.
Publisher: name: Unknown
Year: 1946
Subjects: Community/Rural/Urban Development
Labor and Human Capital

description: Excerpts: I am most thoroughly convinced that a more effective farm program will be put into execution if Extension Service workers and employers will persistently, earnestly, and honestly make a searching effort to find out what actually is the reaction of migrants. Before attempting to relate the findings revealed by these field trips, may I say that, as a Negro, I am fully convinced that very few white men will ever be able to ascertain the innermost private thinking of the Negro migrant. As a result, very few Extension Service employees and farmers actually know an infinitesimal part of what is in the mind of the migrant. Too often, when a white official seeks information, the Negro migrant, unless convinced beyond a doubt that the interviewer is a friend, will shut up like a clam or will furnish the official with information which the migrant thinks pleases the inquirer. I am further convinced that the migrants very frequently withhold information regarding the difficulties which they encounter resulting from poor employer-employee relationships. It is evident that there are several major factors which concern the migrant. --- Acceptable Housing -- Employer-Employee Relationships (Camp Management – Field Management – Transportation – Wages).
description: Presented at the Atlantic Coast Migratory Conference, Baltimore, Md., 2-5-46.
title: Bureau du Cercle de Khémisset
title: Bureau du Cercle de Khémisset
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Urbanisme
subject: Plan d'aménagement

description: Cartographie
description: BESM-carto_1956-69-p032_069-02
description: 32
description: 69
description: Bulletin économique et social du Maroc
description: Source: Maison méditerranéenne des sciences de l'homme, Cité numérique de la Méditerranée (Cinumed), Bibliothèque nationale du Royaume du Maroc (BNRM)
description: Source: Bulletin économique et social du Maroc
description: Source: Bulletin économique et social du Maroc (BESM) > BESM (Cartographie)
description: Relation: https://cinumed.mmsh.univ-aix.fr/idurl/1/81883
description: Coverage: Maroc
description: Coverage: Khémisset
description: Coverage: XXe siècle
description: Temporal: XXe siècle
description: Bibliographic citation: « Bureau du Cercle de Khémisset », In Bulletin économique et social du Maroc (BESM), n° 69, 1956
description: Provenance: Maison méditerranéenne des sciences de l'homme, Cité numérique de la Méditerranée (Cinumed), Bibliothèque nationale du Royaume du Maroc (BNRM)
description: Provenance: https://cinumed.mmsh.univ-aix.fr/
Dibenzo-α-pyrones from the endophytic fungus Alternaria sp. Samif01: isolation, structure elucidation, and their antibacterial and antioxidant activities
Creators: name: Tian, Jin
name: Linyun Fu
name: Zihao Zhang
name: Xuejiao Dong
name: Xu, Dan
name: Ziling Mao
name: Liu, Yang
name: Daowan Lai
name: Ligang Zhou
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: The EtOAc extract of the liquid fermentation of Alternaria sp. Samif01, an endophytic fungus obtained from Salvia miltiorrhiza Bunge, showed antibacterial activity against several tested bacterial pathogens. Fractionation of this extract led to the isolation of seven dibenzo-α-pyrones (1–7), including one new compound, 2-acetoxy-2-epi-altenuene (1) and one new natural product, 3-epi-dihydroaltenuene A (2). The structures of the new metabolites were elucidated by comprehensive analysis of the spectroscopic data including (1D, 2D) NMR and HRESIMS, while the absolute configuration of 1 was determined by TDDFT–ECD computation. Altenuisol (5), 4-hydroxyalternariol-9-methyl ether (6), and alternariol (7) showed inhibitory activities against the tested bacteria with minimum inhibitory concentration values in the range of 86.7–364.7 μM. A preliminary structure–antibacterial activity relationship was discussed. In addition, compounds 2, 5 and 6 displayed promising antioxidant effects using DPPH and hydroxyl radical assays. The cytotoxicity of the isolated compounds was evaluated as well. The endophytic fungus Alternaria sp. Samif01 isolated from Salvia miltiorrhiza Bunge produced seven bioactive dibenzo-α-pyrones, including one new compound (1), whose absolute configuration was determined by ECD calculation.
Additional file 1 of CTHRC1 targeted by miR-30a-5p regulates cell adhesion, invasion and migration in lung adenocarcinoma
Creators: name: Yang, Chaomian
name: Huang, Tianxia
name: Liang, Yue
name: Xue, Yanlong
name: Liang, Ying
name: Wei, Xianqin
name: Meng, Fangchan
name: Wei, Qiu
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 1. LogFC Value of 5 Predicted Upstream miRNAs That May Regulate CTHRC1.
Improving the antifouling properties of ceramic membranes via chemical grafting of organosilanes
Creators: name: Jongman Lee
name: Jang-Hoon Ha
name: In-Hyuck Song
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: For enhanced antifouling surface properties, the alumina membranes were modified through a simple silanization process. Three organosilanes presenting neutral, positive, and negative charges were allowed to graft onto alumina membranes. A small decrease in the pore size and the successful chemical binding of organosilanes were confirmed, respectively. The membrane filtration test using humic acid (HA) was conducted to evaluate the effect of surface charges on fouling resistance. The neutral and negatively charged membranes achieved remarkable flux behaviour due to no charge interaction and electrostatic repulsion force, respectively. Especially, the negatively charged membranes presented the lowest flux decline, the highest flux recovery, and the lowest membrane fouling.
Improving the Antifouling Properties of Ceramic Membranes via Chemical Grafting of Organosilanes
Creators: name: Jongman Lee
name: Jang-Hoon Ha
name: In-Hyuck Song
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: For enhanced antifouling surface properties the alumina membranes were modified through a simple silanization process. Three organosilanes presenting neutral, positive, and negative charges were allowed to graft onto alumina membranes. A small decrease in the pore size and the successful chemical binding of organosilanes were confirmed, respectively. The membrane filtration test using humic acid was conducted to evaluate the effect of surface charges on fouling resistance. The neutral and negatively charged membranes achieved the remarkable flux behavior due to no charge interaction and electrostatic repulsion force, respectively. Especially, the negatively charged membranes presented the lowest flux decline, the highest flux recovery, and the lowest membrane fouling.
Fluorescence bimolecular complementation enables facile detection of ribosome assembly defects in Escherichia coli
Creators: name: Himanshu Sharma
name: Anand, Baskaran
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry
subject: Computational Biology

description: Assembly factors promote the otherwise non-spontaneous maturation of ribosome under physiological conditions inside the cell. Systematic identification and characterization of candidate assembly factors are fraught with bottlenecks due to lack of facile assay system to capture assembly defects. Here, we show that bimolecular fluorescence complementation (BiFC) allows detection of assembly defects that are induced by the loss of assembly factors. The fusion of N and C-terminal fragments of Venus fluorescent protein to the ribosomal proteins uS13 and uL5, respectively, in Escherichia coli facilitated the incorporation of the tagged uS13 and uL5 onto the respective ribosomal subunits. When the ribosomal subunits associated to form the 70S particle, the complementary fragments of Venus were brought into proximity and rendered the Venus fluorescent. Assembly defects that inhibit the subunits association were provoked by either the loss of the known assembly factors such as RsgA and SrmB or the presence of small molecule inhibitors of ribosome maturation such as Lamotrigine and several ribosome-targeting antibiotics and these showed abrogation of the fluorescence complementation. This suggests that BiFC can be employed as a surrogate measure to detect ribosome assembly defects proficiently by circumventing the otherwise cumbersome procedures. BiFC thus offers a facile platform not only for systematic screening to validate potential assembly factors but also to discover novel small molecule inhibitors of ribosome assembly toward mapping the complex assembly landscape of ribosome.
SOVUTGICH QURILMASINING ISHLASH TAMOYILLARI VA TERMODINAMIK SIKLINI O'RGANISH
Creators: name: Rahmanov Valijon, Valijon
name: Omonov, Azizbek
name: Farmonova, Zumrad
name: Turo'unboyeva, Shahlo
Publisher: name: Zenodo
Year: 2024

description: Maqolada sovutgichni sotib olishni xohlaydigan yoki sanoat sovutgichi haqida bilmoqchi bo‘lgan ko‘pchilik odamlar sovutgich qanday ishlashini bilishni istashadi va ular sovutgichning ishlash printsipi to‘o‘risida ham adas hishadi. Sovutgich qanday ishlaydi? Sovutgichning ishlash tamoyillari qanday? Siz uchun hozir javob berishga harakat qilamiz?
Fluorescence Bimolecular Complementation Enables Facile Detection of Ribosome Assembly Defects in Escherichia coli
Creators: name: Himanshu Sharma
name: Anand, Baskaran
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry
subject: Computational Biology

description: Assembly factors promote the otherwise non-spontaneous maturation of ribosome under physiological conditions inside the cell. Systematic identification and characterization of candidate assembly factors are fraught with bottlenecks due to lack of facile assay system to capture assembly defects. Here, we show that bimolecular fluorescence complementation (BiFC) allows detection of assembly defects that are induced by the loss of assembly factors. The fusion of N and C-terminal fragments of Venus fluorescent protein to the ribosomal proteins uS13 and uL5, respectively, in Escherichia coli facilitated the incorporation of the tagged uS13 and uL5 onto the respective ribosomal subunits. When the ribosomal subunits associated to form the 70 S particle, the complementary fragments of Venus were brought into proximity and rendered the Venus fluorescent. Assembly defects that inhibit the subunits association were provoked by either the loss of the known assembly factors such as RsgA and SrmB or the presence of small molecule inhibitors of ribosome maturation such as Lamotrigine and several ribosome-targeting antibiotics abrogated the fluorescence complementation. This suggests that BiFC can be employed as a surrogate measure to detect ribosome assembly defects proficiently by circumventing the otherwise cumbersome procedures. BiFC thus offers a facile platform not only for systematic screening to validate potential assembly factors but also to discover novel small molecule inhibitors of ribosome assembly towards mapping the complex assembly landscape of ribosome.
Cationic liposomes produced via ethanol injection method for dendritic cell therapy
Creators: name: Vitor, Micaela Tamara
name: Bergami-Santos, Patrícia Cruz
name: Zômpero, Rafael Henrique Freitas
name: Cruz, Karen Steponavicius Piedade
name: Pinho, Mariana Pereira
name: Barbuto, José Alexandre Marzagão
name: Lucimara Gaziola De La Torre
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Hematology
subject: Plant Biology
subject: FOS: Biological sciences

description: Cationic liposomes can be designed and developed in order to be an efficient gene delivery system for mammalian cells. Dendritic cell (DC) vaccines can be used to treat cancer, as cationic liposomes can deliver tumor antigens to cells while cells remain active. However, most methods used for liposome production are not able to reproduce in large scale the physicochemical and biological properties of liposomes produced in laboratory scale. In this context, ethanol injection method achieved promising results, although requiring post-treatment for size reduction and/or to remove residual ethanol. Thus, the purpose of this study was to generate cationic liposomes suitable for gene therapies via ethanol injection method in only one step (VEI) and compared to those submitted to a size reduction processes by microfluidization (MFV). For this, the method to produce cationic liposomes composed of egg phosphatidylcholine (EPC), 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) and 1,2-dioleoylphosphatidylethanolamine (DOPE) was optimized using a statistical design approach. As a result, the size of VEI decreased from 290 nm to 110 nm and the polydispersity from 0.54 to 0.17. In the case of MFV, size decreased from 128 nm to 107 nm and polydispersity from 0.40 to 0.18. ST and MFV before and after optimization were also characterized in terms of morphology by transmission electron microscopy (TEM) and structure by differential scanning calorimetry (DSC). Finally, to show their potential in gene/immune therapies applications, DCs were stimulated by such liposomes. Cells internalized liposomes, increasing expression of the costimulatory molecule CD86 and inducing T lymphocyte proliferation.