cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Circulating tumour DNA as a biomarker in the monitoring of neuroendocrine neoplasms and adrenocortical carcinoma
Creators: name: G. Gohil, Shailesh
Publisher: name: University of Leicester
Year: 2024

description: Neuroendocrine neoplasms (NENs) and adrenocortical carcinoma (ACC) are two rare malignancies affecting the endocrine system, which both have a clinical need for novel biomarker development. This thesis assessed the role of detecting and monitoring circulating tumour DNA (ctDNA) for this purpose using a bespoke, tumour informed, personalised approach in 9 patients with metastatic NENs and a case of ACC.Tumour DNA whole exome sequencing (WES) was undertaken to identify tumour specific somatic variants. In the patients with NENs, WES demonstrated that each patient’s tumour was genetically unique and in the patient with ACC, multi-regional WES demonstrated intra-tumoural heterogeneity. Bioinformatics pipelines were applied to filter and select patient-specific variants for targeted next generation sequencing (NGS) and a bespoke, personalised AmpliSeq™ HD assay targeting 132 variants (5-22 unique to each patient) was designed. 125/132 variants were confirmed by NGS analysis of the tumour DNA with statistical concordance of variant allele frequencies (VAFs) with the WES data.For NENs, 35 plasma samples, 2-5 for each patient, collected serially over 2-25 months underwent targeted NGS for ctDNA detection and monitoring. ctDNA was detected in 6/9 patients. In 4 of these patients, ctDNA dynamics tracked disease progression and treatment response. ctDNA was not detected in 3 patients and was associated with their indolent disease. ctDNA therefore correlated with disease activity in 7/9 patients. ctDNA performed equally to chromogranins as a biomarker in 3/8 patients, where chromogranins were monitored, however in 4 patients, ctDNA more accurately reflected with tumour dynamics. In the patient with ACC monitored over 25 months, ctDNA was detected in 2/5 samples at times of disease progression. Fewer ctDNA variants detected in the second positive sample but at higher VAFs were suggestive of clonal evolution. Absence of ctDNA in 3/5 samples was associated with treatment response/indolent disease.This pilot study demonstrates that ctDNA can be detected and monitored in patients with metastatic NENS and ACC and, with further development, could be used as a clinically useful biomarker.
title: Hepatic portal venous gas (HPVG) in children beyond neonatal period – is it always a surgical emergency? Review of ultrasonographic and clinical findings
Creators: name: Barczuk-Falęcka, Marzena
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Education and training
subject: Diagnostic procedure
subject: Ultrasound
subject: Paediatric
subject: Liver

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: to illustrate ultrasonographic findings of hepatic portal venous gas (HPVG) in children, in correlation with clinical findings to review pediatric pathologies with HPVG, which are not considered surgical emergencies to present usefulness of...
LRTM: Examining the Asymmetry in Judgments of Racism in Self and Others
Creators: name: Bell, Angela
name: Bock, Jarrod
Publisher: name: Open Science Framework
Year: 2022

description: Across three experiments, participants were provided with a list of racist behaviors that purportedly were enacted from a fellow student but in fact were based on the participants’ own behaviors. People consistently evaluated themselves as less racist than this comparison other even though this other’s racist behaviors were identical to their own. Studies 2a and 2b demonstrate this effect is quite robust and even occurs under social pressure and social consensus conditions in which participants were free to express their racial biases. Thus, it appears that people are less likely to base their racist trait ratings on behavioral evidence when evaluating themselves compared to when they are evaluating another. Taken together, this work provides evidence for the consistency and robustness of self-enhanced social comparisons as applied to the trait domain of racism. Further, this work sheds insight into why people deny they are racist when they act racist.
Universality of finite time disentanglement
Creators: name: Drumond, Raphael C.
name: Duarte, Cristhiano
name: Cunha, Marcelo Terra
name: Nemes, Maria C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper we investigate how common is the phenomenon of Finite Time Disentanglement (FTD) with respect to the set of quantum dynamics of bipartite quantum states with finite dimensional Hilbert spaces. Considering a quantum dynamics from a general sense, as just a continuous family of Completely Positive Trace Preserving maps (parametrized by the time variable) acting on the space of the bipartite systems, we conjecture that FTD happens for all dynamics but those when all maps of the family are induced by local unitary operations. We prove this conjecture valid for two important cases: i) when all maps are induced by unitaries; ii) for pairs of qubits, when all maps are unital. Moreover, we prove some general results about unitaries/CPTP maps preserving product/pure states
description: 7 pages and 2 figures. New title. Improved version! Comments are welcome
Worksite Health Promotion for Low-Wage Workers: A Scoping Literature Review
Creators: name: Thatcher, Esther
name: Baron, Sherry L.
name: Ornelas, India J.
name: Shivaprakash, Namrata
name: Kneipp, Shawn
name: Muramatsu, Naoko
name: Stiehl, Emily
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: To determine: (1) What research has been done on health promotion interventions for low-wage workers and (2) What factors are associated with effective low-wage workers’ health promotion.
Surrounding Norms Study 2
Creators: name: Bareket-Shavit, Carmelle
name: Schmader, Toni
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: We ask whether egalitarian cultures inform people’s perceptions of harm from an incident of bias and/or their assumptions about a perpetrator’s intentions in a follow-up study. Here, we make small modifications to the Surrounding Norms Survey 1 with some wording changes and changes to the order of survey questions. All changes are highlighted in yellow in the attached pdf.
SLEMEG - An MEG-study on the effects of insufficient sleep on emotional and attentional processes
Creators: name: Gerhardsson, Andreas
name: Lundqvist, Daniel
name: Fischer, Håkan
name: Månsson, Kristoffer
name: Kecklund, Göran
name: Åkerstedt, Torbjörn
name: Schwarz, Johanna
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Experimental Analysis of Behavior
subject: Biological Psychology
subject: Cognitive Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: This study will investigate the effect of two nights of partial sleep deprivation on emotional attention using magnetoencephalography (MEG).
title: HRCT in uncommon occupational lung diseases – Do we need some help?
Creators: name: Buroviené, Vytauté
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Toxicity
subject: Occupational / Environmental hazards
subject: Diagnostic procedure
subject: Contrast agent-intravenous
subject: PACS
subject: Digital radiography
subject: CT-High Resolution
subject: Respiratory system
subject: Mediastinum
subject: Lung

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review the diagnostic steps ofsome uncommon occupational lung diseases (OLD), some of them found in the PACS systems of two tertiary health care institutions - Universitair Ziekenhuis Brussel (Brussels, Belgium) and Hospital of Lithuanian...
test2
Creators: name: Alves, Anna Beatriz Luciano
name: Da Silva Martins, Gabriel
name: Santos, Helen Cristina Silva Dos
name: Oliveira, Patrícia Santos
Publisher: name: Zenodo
Year: 2023
Subjects: Capeamento Pulpar
Tratamento Expectante
Estudos De Séries Temporais
Odontologia
Tratamento Conservador

description: RESUMO Introdução: Processo cariogênico, traumas ou agressões mecânicas podem afetar a harmonia das estruturas dentais. Muitas vezes, há necessidade de utilizar materiais protetores para que não haja perda da integridade do elemento. O capeamento pulpar pode ser realizado de forma direto ou indireta. Os diretos são utilizados quando ocorre a exposição pulpar, seja por cárie ou por iatrogenia. Os capeamentos indiretos são feitos na ausência de exposição pulpar, com apenas grande proximidade. Após a chegada do COVID-19 no Brasil, os dentistas tornaram-se profissionais com alto risco de contaminação cruzada. É relatada a diminuição de aproximadamente 89% no número total de procedimentos executados em saúde bucal. Objetivo: Interpretar dados obtidos sobre o procedimento de tratamento de capeamento pulpar em Imperatriz e o impacto da pandemia no contexto de saúde inserido na discussão. Metodologia: Trata-se de um estudo transversal descritivo de base populacional e série temporal de capeamento pulpares na cidade de Imperatriz-Ma, no período de janeiro a junho/2019 e janeiro a junho/2021. Os dados brutos da incidência foram consultados no banco de dados do Ministério da Saúde Brasileiro (DATASUS/TABNET), como fonte o Sistema de Informações Ambulatoriais do SUS (SIA/SUS). A busca na literatura caracterizou-se com a utilização de dados disponíveis na Biblioteca Virtual de Saúde (BVS), Pubmed, Scielo, Lilacs, Medline e Google Acadêmico. Resultado: No primeiro semestre de 2019, houve cerca de 215 tratamentos expectantes na atenção básica, em Imperatriz-MA; Já em 2021, no mesmo período de análise anterior, realizou-se cerca de 17, refletindo em uma redução de cerca de 92,67% nos procedimentos de capeamento pulpar, por elemento. Essa redução dá-se pelo contexto de suspensão das atividades em meio a pandemia. Conclusão: Segundo a análise de dados, foi levantado que o período pandêmico teve impacto negativo sobre os serviços prestados no atendimento público. Tornando-se necessária a implementação de estratégias para controle da demanda.
Implementation of inpatient models of pharmacogenetics programs
Creators: name: Nutescu, Edith A.
name: Cavallari, Larisa H.
name: Stouffer, George A.
name: Duarte, Julio D.
name: Lee, Craig R.
name: Weitzel, Kristin W.
name: Johnson, Julie A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The operational elements essential for establishing an inpatient pharmacogenetic service are reviewed, and the role of the pharmacist in the provision of genotype-guided drug therapy in pharmacogenetics programs at three institutions is highlighted.
Searching for I band variability in stars in the M/L spectral transition region
Creators: name: Ramsay, Gavin
name: Hakala, Pasi
name: Doyle, J Gerry
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report on I band photometric observations of 21 stars with spectral types between M8 and L4 made using the Isaac Newton Telescope. The total amount of time for observations which had a cadence of <2.3 mins was 58.5 hrs, with additional data with lower cadence. We test for photometric variability using the Kruskal-Wallis H-test and find that 4 sources (2MASS J10224821+5825453, 2MASS J07464256+2000321, 2MASS J16262034+3925190 and 2MASS J12464678+4027150) were found to be significantly variable at least on one epoch. Three of these sources are reported as photometrically variable for the first time. If we include sources which were deemed marginally variable, the number of variable sources is 6 (29 percent). No flares were detected from any source. The percentage of sources which we found were variable is similar to previous studies. We summarise the mechanisms which have been put forward to explain the light curves of brown dwarfs.
description: Accepted MNRAS 6 pages
Asthma and neuroinflammation
Creators: name: Nair, Ajay
name: Rosenkranz, Melissa
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medical Sciences
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Medicine and Health Sciences
subject: Medical Immunology
subject: Alzheimer's Disease
subject: Asthma
subject: Cognition
subject: Neurodegeneration
subject: Neuroinflammation

description: This project aims to understand the effects of asthma on brain health by examining levels of CSF markers of neuroinflammation, neurodegeneration and Alzheimer's Disease pathology. It will also examine the effects of asthma on cognitive performance. This study will use previously acquired CSF data and will use asthma medications as a proxy for asthmatic status.
Supplementary document for Synchronized strobed phase contrast and fluorescence microscopy: the interlaced standard reimagined - 6032172.pdf
Creators: name: Hosu, Basarab
name: Hill, Winfield
name: Samuel, Aravinthan
name: Berg, Howard
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biophysics
subject: Biological Techniques

description: Supplement 1 - supplemental text and figures
Recommendations for selecting drug-drug interactions for clinical decision support
Creators: name: Bates, David W.
name: Grizzle, Amy J.
name: Huang, Shiew-Mei
name: Weinstein, David M.
name: Vieson, Kathleen
name: Hansten, Philip D.
name: Tilson, Hugh
name: McEvoy, Gerald
name: Hines, Lisa E.
name: Hanlon, Joseph T.
name: Matuszewski, Karl
name: Brown, Mary
name: Helwig, Amy L.
name: Wittie, Michael A.
name: Higby-Baker, Stefanie
name: Malone, Daniel C.
name: Pezzullo, Lynn
name: Perre, Anthony
name: Le Comte, Marianne
name: Poikonen, John
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: To recommend principles for including drug-drug interactions (DDIs) in clinical decision support.
Encoding context determines risky choice
Creators: name: Madan, Christopher
name: Ludvig, Elliot
name: Spetch, Marcia
name: Mason, Alice
name: Machado, Fernanda
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Cognitive Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: behavioral economics
subject: decisions from experience
subject: memory
subject: memory biases
subject: risky decision making

description: Both memory and decision processes are strongly influenced by the context in which they occur. Here we examined how fluid these context effects are and whether transient background contexts can influence risky choice in experience-based decision making. We created two separate background contexts within an experimental session by presenting distinctive visual cues for blocks of trials involving different decision sets. Risky choices were highly context dependent: Choices reflected an overweighting of the most extreme outcomes within each background context, rather than the global session-level context. In particular, given the exact same risky decision, participants chose differently depending on the other possible outcomes in that background context. Furthermore, follow-up memory tests demonstrated that people displayed memory biases that were specific to the distinct contexts and also consistent with their choice patterns. Thus, the decision contexts were discretized in memory, and, for each context-dependent decision set, the outcomes at the extremes of that distribution were overweighted.
De novo CD5+ diffuse large B-cell lymphoma: Adverse outcomes with and without stem cell transplantation in a large, multicenter, rituximab treated cohort: CD5 positivity affects DLBCL outcome
Creators: name: Abramson, Jeremy S.
name: Iris Lim, Hana
name: Kreisel, Friederike
name: Singavi, Arun
name: Quinion, Carl
name: Oak, Eunhye
name: Evens, Andrew
name: Gru, Alejandro
name: Lozanski, Gerard
name: Poston, Jacqueline
name: Blum, Kristie A.
name: Fenske, Timothy S.
name: Venkataraman, Girish
name: Matthews, Stephanie
name: Martin, Peter
name: Park, Steven I.
name: Huang, Ying
name: Al-Mansour, Zeina
name: Cohen, Jonathon B.
name: Alinari, Lapo
name: Lozanski, Arletta
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: De novo CD5+ diffuse large B-cell lymphomas (DLBCL) are a distinct subgroup of DLBCL with poor prognosis. However the role of rituximab-containing therapy and salvage stem cell transplantation in this patients’ population remain to be defined. We retrospectively reviewed clinical features and outcomes of 102 patients with de novo CD5+ DLBCL treated with rituximab-containing therapy at 9 different institutions. By Hans’ criteria, 64 patients had activated B-cell (ABC) subtype, 24 germinal center B-cell (GCB) subtype, and 14 were not evaluated. No patients had a myc translocation. Eighty-three patients were treated with rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone (R-CHOP), 7 with rituximab, etoposide, cyclophosphamide, doxorubicin, vincristine, prednisone (R-EPOCH) and 6 with R-CHOP with methotrexate, 3 g/m2. The overall response rate to frontline therapy was 85%. The 3-year progression free survival (PFS) and overall survival (OS) for all patients were 40% and 65%, respectively. The 3-year PFS for ABC- and GCB-subtypes was 34% and 45%, respectively. The 3-year OS for ABC- and GCB-subtypes was 62% and 67%, respectively. The median time to second treatment failure was 3 months and 1 month for ABC- and GCB-subtypes, respectively. Twenty of 28 (71%) transplanted patients with autologous, allogeneic, or both, relapsed. This study confirms the poor prognosis of de novo CD5+ DLBCL in a large multi-center cohort despite initial rituximab-containing chemotherapy and suggests that stem cell transplantation fails to salvage the majority of these patients. Approaches to prevent recurrence and/or novel therapies for relapsed disease are needed for this subgroup of DLBCL patients.
Evidence for non-ergodicity in quiescent states of periodically sheared suspensions
Creators: name: Schrenk, K. Julian
name: Frenkel, Daan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: We present simulations of an equilibrium statistical-mechanics model that uniformly samples the space of quiescent states of a periodically sheared suspension. In our simulations, we compute the structural properties of this model as a function of density. We compare the results of our simulations with the structural data obtained in the corresponding non-equilibrium model of Corté et al. [Nat. Phys. 4, 420 (2008)]. We find that the structural properties of the non-equilibrium model are very different from those of the equilibrium model, even though the two models have exactly the same set of accessible states. This observation shows that the dynamical protocol does not sample all quiescent states with equal probability. In particular, we find that, whilst quiescent states prepared in a non-equilibrium protocol can be hyperuniform [see Phys. Rev. Lett. 114, 110602 (2015), Phys. Rev. Lett. 114, 148301 (2015), and Phys. Rev. Lett. 115, 108301 (2015)], ergodic sampling never leads to hyperuniformity. In addition, we observe ordering phase transitions and a percolation transition in the equilibrium model that do not show up in the non-equilibrium model. Conversely, the quiescent-to-diffusive transition in the dynamical model does not correspond to a phase transition, nor a percolation transition, in the equilibrium model.
Small- and Large-scale Characterization and Mixing Properties in a Thermally Driven Thin Liquid Film
Creators: name: Winkler, Michael
name: Abel, Markus
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Thin liquid films are nanoscopic elements of foams, emulsions and suspensions, and form a paradigm for nanochannel transport that eventually test the limits of hydrodynamic descriptions. Here we use classical dynamical systems characteristics to study the complex interplay of thermal convection, interface and gravitational forces which yields turbulent mixing and transport: Lyapunov exponents and entropies. We induce a stable two eddy convection in an extremely thin liquid film by applying a temperature gradient. Experimentally, we determine the small-scale dynamics using the motion and deformation of spots of equal size/equal color, we dubbed that technique "color imaging velocimetry". The large-scale dynamics is captured by encoding the left/right motion of the liquid directed to the left or right of the separatrix between the two rolls. This way, we characterize chaos of course mixing in this peculiar fluid geometry of a thin, free-standing liquid film.
title: Detection of Uterine Vascular Malformations Using 4D-CT Angiography: Initial Experience
Creators: name: El-Sharkawy, Ahmed
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Arterial access
subject: Computer Applications-3D
subject: PACS
subject: Catheter arteriography
subject: CT-Angiography
subject: Vascular
subject: Interventional vascular
subject: Genital / Reproductive system female
subject: Computer Applications-Detection, diagnosis
subject: Arteriovenous malformations
subject: Aneurysms
subject: Obstetrics

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Usage of dynamic CT Angiography ( 4D-CTA ) in detection of uterine vascular malformations. Clarify feeding arteries and draining veins of the vascular malformations before uterine artery embolization ( UAE...
Bootstrapping ${\mathcal N}=2$ chiral correlators
Creators: name: Lemos, Madalena
name: Liendo, Pedro
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We apply the numerical bootstrap program to chiral operators in four-dimensional ${\mathcal N}=2$ SCFTs. In the first part of this work we study four-point functions in which all fields have the same conformal dimension. We give special emphasis to bootstrapping a specific theory: the simplest Argyres-Douglas fixed point with no flavor symmetry. In the second part we generalize our setup and consider correlators of fields with unequal dimension. This is an example of a mixed correlator and allows us to probe new regions in the parameter space of ${\mathcal N}=2$ SCFTs. In particular, our results put constraints on relations in the Coulomb branch chiral ring and on the curvature of the Zamolodchikov metric.
description: 35 pages (26 pages plus three appendices), 13 figures; v2: minor typos corrected, citations added
Meta-Analyses of the Convergent Validity of the Personality Assessment Inventory (PAI) Clinical Scales
Creators: name: detullio, david
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Meta-analysis
subject: Personality Assessment Inventory
subject: Psychological Assessment

description: The aim of this project is to meta-analytically evaluate the convergent validity of the interpretations for the 11 PAI clinical scales.
Determination of CP violation parameter using neutrino pair beam
Creators: name: Yoshimura, M.
name: Sasao, N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Neutrino oscillation experiments under neutrino pair beam from circulating excited heavy ions are studied. It is found that detection of double weak events has a good sensitivity to measure CP violating parameter and distinguish mass hierarchy patterns in short baseline experiments in which the earth-induced matter effect is minimized.
description: 9 pages, 6 figures
Identifying existing Choosing Wisely recommendations of high relevance and importance to hematology
Creators: name: Ma, Alice
name: Bering, Harriet
name: Panepinto, Julie A.
name: Mueller, Brigitta U.
name: Kukreti, Vishal
name: Rajasekhar, Anita
name: Sarode, Ravi
name: Carson, Kenneth R.
name: Hicks, Lisa K.
name: Wood, William A.
name: O'Brien, Sarah H.
name: Kleinerman, Judith
name: Pasquini, Marcelo C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Choosing Wisely (CW) is a medical stewardship initiative led by the American Board of Internal Medicine Foundation in collaboration with professional medical societies in the United States. In an effort to learn from and leverage the work of others, the American Society of Hematology CW Task Force developed a method to identify and prioritize CW recommendations from other medical societies of high relevance and importance to patients with blood disorders and their physicians. All 380 CW recommendations were reviewed and assessed for relevance and importance. Relevance was assessed using the MORE TM relevance scale. Importance was assessed with regard to six guiding principles: harm avoidance, evidence, aggregate cost, relevance, frequency and impact. Harm avoidance was considered the most important principle. Ten highly relevant and important recommendations were identified from a variety of professional societies. Recommendations focused on decreasing unnecessary imaging, blood work, treatments and transfusions, as well as on increasing collaboration across disciplines and considering value when recommending treatments. Many CW recommendations have relevance beyond the society of origin. The methods developed by the ASH CW Task Force could be easily adapted by other Societies to identify additional CW recommendations of relevance and importance to their fields. Am. J. Hematol. 91:787–792, 2016. © 2016 Wiley Periodicals, Inc.
Governing patient safety through law, policy and institutional frameworks in Bangladesh: opportunities and challenges
Creators: name: Karim, Sheikh Mohammad Towhidul
Publisher: name: Macquarie University
Year: 2023
Subjects: classificationCode: 399999
subject: Other education not elsewhere classified

description: Bangladesh has suffered numerous healthcare crises. The country currently lacks a coherent legal, policy and institutional framework to promote patient safety in healthcare, with inadequate mechanisms to enforce standards or provide access to justice for patients aggrieved by breaches of care standards. To date, patients have no real recourse to submit complaints concerning medical malpractice and the enforcement culture fails to promote accountability among medical professionals. This has contributed to a high incidence of medical malpractice, adverse events and medical errors. This thesis is mainly focused on three main challenges: 1) health governance, 2) a code of medical ethics and 3) judicial commitment to promote patient safety and hold the healthcare system accountable for quality healthcare service. This thesis critically reviews and evaluates the healthcare framework, particularly patient safety legislation and the supporting tools and institutions that promote patient safety in Bangladesh. This thesis draws upon both theories of human rights and governance to develop recommendations for law and policy reforms that will promote the right to health and patient safety in accordance with international law. It will also consider the code of ethics of health professionals in regard to patient safety. This thesis further examines the potential role of the judiciary in reinforcing healthcare outcomes for citizens of Bangladesh. It argues that judicial intervention, through the interpretation of domestic and international law, may provide a viable mechanism and function as a ‘catalyst’ for strengthening governance, fulfilling the main claim of this thesis. The thesis makes significant contributions to the field of quality healthcare services research by way of reviewing relevant law, policy and institutional frameworks regarding patient care and safety and suggesting avenues for law and policy reform.
title: "Better three hours too soon than a minute too late”- understanding the key imaging features and impact of detection of inflammatory aortic aneurysm
Creators: name: Singhal, Soumil
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Aneurysms
subject: Surgery
subject: MR-Angiography
subject: CT-Angiography
subject: Arteries / Aorta
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: An aneurysm in simple means a focal dilatation of a blood vessel, most common cause of which results due to atherosclerosis, few uncommon causes have also been described among which I nflammatory abdominal aortic aneurysm stands out as one of the...
On peculiarities of superconductivity in the single-layer FeSe/SrTiO3 interfa
Creators: name: Gor'kov, Lev P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Observation of replica bands in the ARPES spectra of the single-layer FeSe on strontium titanate substrate revealed a phonon component among mechanisms behind high Tc superconductivity there. We study the interaction of the in-layer FeSe electrons with the electric potential of the longitudinal (LO) modes at surface of bulk SrTiO3. A two-dimensional system of charges at the FeSe/SrTiO3 interface includes both the itinerant and immobile electrons. The latter significantly change the interface characteristics, increasing screening at the substrate surface and reducing thereby the strength of the electron-LO phonon interactions. In that follows the dielectric constant serves as a free parameter and is found from the ARPES data for the replicas. The two-dimensional Coulomb screening is accounted for in the random phase approximation. It is shown that the model is applicable within the whole range of the parameters typical for current experiments. The estimates allow concluding that the LO-phonon mediated pairing alone cannot account for the temperatures of the superconducting transition Tc in the single-layer FeSe/SrTiO3 reported in these experiments. This does not exclude that the LO-phonons mechanism can become more significant in the differently and better prepared single layer FeSe films. Available experiments are briefly discussed. Thus far no data exist on the dependence of Tc on the concentration of electrons doped into the in-layer FeSe band.
title: LIRADS: injury management in patients at risk of hepatocellular carcinoma.
Creators: name: RAYA NUÑEZ, MARIA JOSE
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Image registration
subject: Education and training
subject: Education
subject: MR
subject: CT
subject: Management
subject: Liver
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Normal 0 21 false false false ES-TRAD JA X-NONE To review and ilustrate Liver Imaging Reporting and Data System (LI-RADS) last version categories and standarized criteria . To describe mayor and ancillary features and observations in patients with...
A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade
Creators: name: Mackman, Nigel
name: Vincent, Lucile
name: Vercellotti, Gregory M.
name: Somani, Arif
name: Hebbel, Robert P.
name: Kelm, Robert J.
name: Gupta, Kalpna
name: Pawlinski, Rafal
name: Belcher, John D.
name: Solovey, Anna
name: O'Sullivan, M. Gerard
name: Nath, Karl A.
name: Milbauer, Liming
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Elaboration of tumor necrosis factor (TNF) is a very early event in development of ischemia/reperfusion injury pathophysiology. Therefore, TNF may be a prominent mediator of endothelial cell and vascular wall dysfunction in sickle cell anemia, a hypothesis we addressed using NY1DD, S+SAntilles, and SS‐BERK sickle transgenic mice. Transfusion experiments revealed participation of abnormally activated blood monocytes exerting an endothelial activating effect, dependent upon Egr‐1 in both vessel wall and blood cells, and upon NFκB(p50) in a blood cell only. Involvement of TNF was identified by beneficial impact from TNF blockers, etanercept and infliximab, with less benefit from an IL‐1 blocker, anakinra. In therapeutic studies, etanercept ameliorated multiple disturbances of the murine sickle condition: monocyte activation, blood biomarkers of inflammation, low platelet count and Hb, vascular stasis triggered by hypoxia/reoxygenation (but not if triggered by hemin infusion), tissue production of neuro‐inflammatory mediators, endothelial activation (monitored by tissue factor and VCAM‐1 expression), histopathologic liver injury, and three surrogate markers of pulmonary hypertension (perivascular inflammatory aggregates, arteriolar muscularization, and right ventricular mean systolic pressure). In aggregate, these studies identify a prominent—and possibly dominant—role for an abnormal monocyte‐TNF‐endothelial activation axis in the sickle context. Its presence, plus the many benefits of etanercept observed here, argue that pilot testing of TNF blockade should be considered for human sickle cell anemia, a challenging but achievable translational research goal.
Supplementary document for Efficient, gigapixel-scale, aberration-free whole slide scanner using angular ptychographic imaging with closed-form solution - 7177988.pdf
Creators: name: Zhao, Shi
name: Zhou, Haowen
name: lin, Siyu
name: Cao, Ruizhi
name: Yang, Changhuei
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: Supplementary Document
Explicit Densities of Multidimensional Lévy Walks
Creators: name: Magdziarz, Marcin
name: Zorawik, Tomasz
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We provide explicit formulas for asymptotic densities of the 2- and 3-dimensional ballistic Lévy walks. It turns out that in the 3D case the densities are given by elementary functions. The densities of the 2D Lévy walks are expressed in terms of hypergeometric functions and the right-side Riemann-Liouville fractional derivative which allows to efficiently evaluate them numerically. The theoretical results agree with Monte-Carlo simulations. The obtained functions solve certain differential equations with the fractional material derivative.
title: Diffusion MR imaging using Multi-band EPI in Brain: Basics and its Clinical Application
Creators: name: Hori, Masaaki
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: CNS
subject: MR physics
subject: MR
subject: MR-Diffusion/Perfusion
subject: Physics
subject: Imaging sequences
subject: Neoplasia
subject: Congenital

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Multi-band echo-planar imaging (MB-EPI) (1) is an emerging and important MR technique for recent advanced diffusion MRI (dMRI). We discuss the basics of multi-band echo-planar imaging and describe potential clinical applications of dMRI using...
Push button reproduction attempt of a research claim from Fangwen Lu and Michael L. Anderson, (2015), in Journal of Labor Economics
Creators: name: Tutor, Melba
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: Claim paragraph (from the sourcing sheet): For a female student, being surrounded by five females rather than by five males increases her test scores by 0.2 – 0.3 standard deviations. This reflects the following statement from the paper's abstract: "We find that being surrounded by five females rather than five males increases a female’s test scores by 0.2 – 0.3 standard deviations..." The analysis is based on an experiment implemented in a coeducational public middle school in Jiangsu, China. In the experiment, a research group in the local Department of Education randomly assigned students’ seats with input from the authors. The assignment procedure involved first nonrandomly assigning a small number of students and then randomly assigning the remaining students to the remaining seats. The data for this study consist of three rounds of test scores and two rounds of surveys for students of grade 7 in fall 2009. The baseline test and baseline survey were administrated during the first week of the semester before random seat assignment. Given the within-block randomization of seats, the authors estimate the main effects of peers by regressing the mean standardized midterm and final scores for a student in a given block and class on the gender of the desk mate and surrounding neighbors, as well as all of the focal student’s baseline characteristics (gender, baseline test score, height, age, birth order, mother’s and father’s education, and interest in Chinese, math, and English), an indicator for whether the focal student’s desk mate is a favored student, and the share of favored students among the focal student’s neighboring peers, along with block fixed effects. Statistical inference is performed using exact permutation tests. In the model selected as evidence for the SCORE program (Table 5, Panel B, Column 1), the model is estimated on the sample of female students and the effect of the desk mate and neighbor 4 students are combined. Column 1 of panel B in Table 5 demonstrates that female students have positive and statistically significant effects on neighboring female students (0.21 standard deviations, SE clustered by classroom = 0.08, permutation-based p-value = .021). This estimate implies that moving a female student from an all-boy microenvironment to an all-girl microenvironment increases her test scores by approximately 0.2 standard deviations. The focal test in the original paper is: Moving a female student from an all-boy microenvironment to an all-girl microenvironment increases her test scores by approximately 0.2 standard deviations.
Bayesian High-Redshift Quasar Classification from Optical and Mid-IR Photometry
Creators: name: Richards, Gordon T.
name: Myers, Adam D.
name: Peters, Christina M.
name: Krawczyk, Coleman M.
name: Chase, Greg
name: Ross, Nicholas P.
name: Fan, Xiaohui
name: Jiang, Linhua
name: Lacy, Mark
name: McGreer, Ian D.
name: Trump, Jonathan R.
name: Riegel, Ryan N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We identify 885,503 type 1 quasar candidates to i<22 using the combination of optical and mid-IR photometry. Optical photometry is taken from the Sloan Digital Sky Survey-III: Baryon Oscillation Spectroscopic Survey (SDSS-III/BOSS), while mid-IR photometry comes from a combination of data from the Wide-Field Infrared Survey Explorer (WISE) "ALLWISE" data release and several large-area Spitzer Space Telescope fields. Selection is based on a Bayesian kernel density algorithm with a training sample of 157,701 spectroscopically-confirmed type-1 quasars with both optical and mid-IR data. Of the quasar candidates, 733,713 lack spectroscopic confirmation (and 305,623 are objects that we have not previously classified as photometric quasar candidates). These candidates include 7874 objects targeted as high probability potential quasars with 3.53.5 than the traditional mid-IR selection "wedges" and to 2.23. This catalog paves the way for luminosity-dependent clustering investigations of large numbers of faint, high-redshift quasars and for further machine learning quasar selection using Spitzer and WISE data combined with other large-area optical imaging surveys.
description: 54 pages, 17 figures; accepted by ApJS Data for tables 1 and 2 available at http://www.physics.drexel.edu/~gtr/outgoing/optirqsos/data/master_quasar_catalogs.011414.fits.bz2 and http://www.physics.drexel.edu/~gtr/outgoing/optirqsos/data/optical_ir_quasar_candidates.052015.fits.bz2
Formation of bubbly horizon in liquid-saturated porous medium by surface temperature oscillation
Creators: name: Goldobin, Denis S.
name: Krauzin, Pavel V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: We study non-isothermal diffusion transport of a weakly-soluble substance in a liquid-saturated porous medium being in contact with the reservoir of this substance. The surface temperature of the porous medium half-space oscillates in time, which results in a decaying solubility wave propagating deep into the porous medium. In such a system, the zones of saturated solution and non-dissolved phase coexist with the zones of undersaturated solution. The effect is firstly considered for the case of annual oscillation of the surface temperature of water-saturated ground being in contact with atmosphere. We reveal the phenomenon of formation of a near-surface bubbly horizon due to the temperature oscillation. An analytical theory of the phenomenon is developed. Further, the treatment is extended to the case of higher frequency oscillations and case of weakly-soluble solids and liquids.
description: 8 pages, 4 figures, accepted to Physical Review E
Large anharmonic effect and thermal expansion anisotropy of metal chalcogenides: The case of antimony sulfide
Creators: name: Gan, Chee Kwan
name: Soh, Jian Rui
name: Liu, Yun
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We derive a compact matrix expression for the linear thermal expansion coefficients (TECs) for a general orthorhombic system which relates the elastic properties and the integrated quantities based on deformation and mode dependent Gruneisen parameters and mode dependent heat capacities. The density of Gruneisen parameters $Γ(ν)$ as a function of frequency $ν$, weighted by the number of phonon modes, is introduced and found to be insightful in interpreting the TEC results. Using density-functional perturbation theory and Gruneisen formalism for thermal expansion, we illustrate the general usefulness of this method by calculating the linear and volumetric TECs of a low-symmetry orthorhombic compound antimony sulfide (Sb2S3), a compound belonging to a large class of technologically and fundamentally important materials. Even though negative Gruneisen parameters are found for deformations in all three crystal directions, the $Γ(ν)$ data rule out the occurrences of negative TECs at all temperatures. Sb2S3 exhibits a large thermal expansion anisotropy where the TEC in the $b$ direction can reach as high as $13\times 10^{-6}$~(1/K) at high temperatures, about two and seven times larger than the TECs in the $c$ and $a$ direction, respectively. Our work suggests a general and practical first-principles approach to calculate the thermal properties of other complicated low-symmetry systems.
description: 4 pages, 4 figures
title: T2*-weighted perfusion MRI imaging biomarkers obtained at the peritumoral area of high-grade gliomas relate to patients survival
Creators: name: Sanz-Requena, Roberto
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: Oncology
subject: Computer applications
subject: MR-Diffusion/Perfusion
subject: Computer Applications-Detection, diagnosis
subject: Contrast agent-intravenous
subject: Statistics
subject: Tissue characterisation
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Variable tissue infiltration is a characteristic of astrocytoma. It is known that the peritumoral area, defined as non-enhancing peripheral T2-weighted hyperintense region, might contain normal tissue, anomalous vessels, edema and infiltrating...
Predictors of Preference for Hospice Care Among Diverse Older Adults
Creators: name: Edwards, Lloyd J.
name: Williams, Sharon W.
name: Cagle, John G.
name: Pek, Jolynn
name: LaMantia, Michael A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The purpose of this study was to identify predictors of preference for hospice care and explore whether the effect of these predictors on preference for hospice care were moderated by race.
Trust Building Recruitment Strategies for Researchers Conducting Studies in African American (AA) Churches: Lessons Learned
Creators: name: Bonner, Gloria
name: Peacock, Geraldine
name: Hart, Alysha
name: Wilkie, Diana
name: Burnett, Glenda
name: Williams, Sharon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: An initial and vital important step in recruiting participants for church-based hospice and palliative care research is the establishment of trust and credibility within the church community. Mistrust of medical research is an extremely important barrier hindering recruitment in African American (AA) communities. A church-based EOL dementia education project is currently being conducted at four large urban AA churches. Church leaders voiced mistrust concerns of previous researchers who conducted investigations in their faith-based institutions. We explored strategies to ameliorate the mistrust concerns.
A Systematic Review Of The Literature Relating to Strange-Face Illusions
Creators: name: Mash, Joanna
name: Laws, Keith
name: Jenkinson, Paul
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Psychiatry and Psychology
subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: "Strange-Face Illusions"

description: The systematic review proposed in this pre-registration will examine published and grey literature surrounding the phenomena known as “Strange-Face” illusions (Caputo, 2010). This review is unique in that it focusses specifically on evaluating the literature relating to SF illusions from a contemporary cognitive neuroscience / perceptual theory perspective. To the authors’ knowledge this is the first independent review focussing on this particular area of interest since the original study describing the emergence of this phenomena, under mild sensory deprivation conditions, was first published by Caputo in 2010.