Additional file 1 of Anti-hypertensive medication adherence, socioeconomic status, and cognitive aging in the Chinese community-dwelling middle-aged and older adults ≥ 45 years: a population-based longitudinal study
Creators: name: Li, Chenglong
name: He, Daijun
name: Liu, Yufan
name: Yang, Chao
name: Zhang, Luxia
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file 1: Supplemental Methods. Details of cognitive function assessment in the CHARLS. Table S1. Item-response probabilities for the latent class analysis for classifying socioeconomic status. Table S2. Comparison of socioeconomic status indicators by identified latent classes. Table S3. Baseline characteristics of participants by longitudinal adherence to anti-hypertensive medication. Table S4. Associations between anti-hypertensive medication use and the annual rate of change in cognitive function, further excluding individuals with reported memory-related disease or developed cognitive impairment during wave 1 and wave 2. Table S5. Associations between anti-hypertensive medication use and the annual rate of change in cognitive function, further accounting for the use of Chinese traditional medicine. Table S6. Associations between anti-hypertensive medication use and annual rate of change in cognitive function, accounting for other cognitive domains. Table S7. Associations between anti-hypertensive medication use and annual rate of change in cognitive function, further controlling for blood pressure follow-up measurements. Table S8. Associations between anti-hypertensive medication use and the annual rate of change in cognitive function, controlling for the overall socioeconomic status. Table S9. Associations between anti-hypertensive medication use and the annual rate of change in cognitive function, controlling for all indicators of socioeconomic status. Table S10. Associations between overall socioeconomic status and the annual rate of change in cognitive function, controlling for anti-hypertensive medication use. Table S11. Associations between baseline cognition and follow-up cognitive changes with the adherence to anti-hypertensive medication in participants with hypertension. Table S12. Associations between longitudinal anti-hypertensive medication adherence and the annual rate of change in cognitive function, incorporating data from wave 1 to wave 4. Table S13. Associations between anti-hypertensive medication use and the annual rate of change in cognitive function, based on inverse probability-weighted samples. Table S14. Baseline characteristics comparison between participants included and excluded from analysis in CHARLS. Figure S1. Participants selection diagram. Figure S2. Joint associations of baseline anti-hypertensive medication use and socioeconomic status with declines in global cognition. Figure S3. Joint associations of baseline anti-hypertensive medication use and socioeconomic status with declines in memory function. Figure S4. Joint associations of longitudinal anti-hypertensive medication adherence and socioeconomic status with declines in global cognition. Figure S5. Joint associations of longitudinal anti-hypertensive medication adherence and socioeconomic status with declines in memory function. Figure S6. Love plot assessing the difference in baseline characteristics between participants included in and excluded from the primary analysis, before and after inverse probability weighting. Figure S7. Joint associations of baseline anti-hypertensive medication use and baseline age with cognitive aging. Figure S8. Joint associations of longitudinal anti-hypertensive medication adherence and baseline age with cognitive aging.