Additional file 1 of Maternal and neonatal outcomes with the use of long acting, compared to intermediate acting basal insulin (NPH) for managing diabetes during pregnancy: a systematic review and meta-analysis
Creators: name: Wang, Jijiao
name: Ji, Xiaochen
name: Liu, Ting
name: Zhao, Nan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health

description: Additional file 1: Table S1. Search strategy for identification of studies to be included in the review. Table S2. Certainty of pooled estimates assessed using GRADE criteria. Table S3. Author’s judgements about study quality using the adapted Ottawa-Newcastle Risk of Bias Assessment tool. Figure S1. Risk of bias summary: review authors’ judgements about each risk of bias item for each included randomised controlled study. Figure S2. Risk of bias graph: review authors’ judgements about each risk of bias item presented as percentages across all included randomised controlled studies. Figure S3. Funnel plot for maternal hypoglycaemia as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S4. Funnel plot for caesarean delivery as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S5. Funnel plot for hypertensive disorder as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S6. Maternal outcomes in women with gestational diabetes receiving glargine, compared to intermediate acting neutral protamine Hagedron. Figure S7. Maternal gestational weight gain (Kg) and glycosylated haemoglobin (HbA1c, %) in women with gestational diabetes receiving glargine, compared to intermediate acting neutral protamine Hagedron. Figure S8. Maternal outcomes in women with gestational diabetes receiving detemir, compared to intermediate acting neutral protamine Hagedron. Figure S9. Maternal gestational weight gain (Kg) and glycosylated haemoglobin (HbA1c, %) in women with gestational diabetes receiving detemir, compared to intermediate acting neutral protamine Hagedron. Figure S10. Funnel plot for preterm birth as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S11. Funnel plot for large for gestational age as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S12. Funnel plot for small for gestational age as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S13. Funnel plot for congenital malformation as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S14. Funnel plot for perinatal mortality as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S15. Funnel plot for admission to NICU as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S16. Funnel plot for neonatal hypoglycaemia as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S17. Funnel plot for APGAR score less than 7 as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S18. Funnel plot for neonatal hyperbilirubinemia as an outcome of interest in women with gestational diabetes receiving long-acting insulin analogues (glargine and/or detemir), compared to intermediate acting neutral protamine Hagedron. Figure S19. Neonatal outcomes in women with gestational diabetes receiving glargine, compared to intermediate acting neutral protamine Hagedron. Figure S20. Neonatal outcomes (continued) in women with gestational diabetes receiving glargine, compared to intermediate acting neutral protamine Hagedron. Figure S21. Gestational age (in weeks) and birth weight (in grams) in new-borns with mother having gestational diabetes and receiving glargine, compared to intermediate acting neutral protamine Hagedron. Figure S22. Neonatal outcomes in women with gestational diabetes receiving detemir, compared to intermediate acting neutral protamine Hagedron. Figure S23. Neonatal outcomes (continued) in women with gestational diabetes receiving detemir, compared to intermediate acting neutral protamine Hagedron. Figure S24. Gestational age (in weeks) and birth weight (in grams) in new-borns with mother having gestational diabetes and receiving detemir, compared to intermediate acting neutral protamine Hagedron.