cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Modular elliptic curves over real abelian fields and the generalized Fermat equation $x^{2\ell}+y^{2m}=z^p$
Creators: name: Anni, Samuele
name: Siksek, Samir
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11D41, 11F80 (Primary), 11G05, 11F41 (Secondary)

description: Using a combination of several powerful modularity theorems and class field theory we derive a new modularity theorem for semistable elliptic curves over certain real abelian fields. We deduce that if $K$ is a real abelian field of conductor $n<100$, with $5 \nmid n$ and $n \ne 29$, $87$, $89$, then every semistable elliptic curve $E$ over $K$ is modular. Let $\ell$, $m$, $p$ be prime, with $\ell$, $m \ge 5$ and $p \ge 3$.To a putative non-trivial primitive solution of the generalized Fermat $x^{2\ell}+y^{2m}=z^p$ we associate a Frey elliptic curve defined over $\mathbb{Q}(ζ_p)^+$, and study its mod $\ell$ representation with the help of level lowering and our modularity result. We deduce the non-existence of non-trivial primitive solutions if $p \le 11$, or if $p=13$ and $\ell$, $m \ne 7$.
description: Introduction rewritten to emphasise the new modularity theorem. Paper revised in the light of referees' comments
HOOU an der TUHH : Jahresbericht 2020
Creators: name: Ladwig, Tina
name: Watolla, Ann-Kathrin
name: Carmesin, Tina
name: Dürkop, Axel
name: Dublasky, Stephan
name: Schielein, Dorothee
name: Burkhardt, Christin
name: Busch, Philip
name: Christiansen, Alexander
name: Drücker, Sven
name: Gruhn, Angelika
name: Hagen, Florian
name: Haschke, Henning
name: Husung, Julia
name: Lainé, Anna
name: Lehmann, Jennifer
name: Nasika, Durga Prasad Babu
name: Rödl, Anne
name: Schaldach, Ruth
name: Schmeink, Lars
name: Scholz, Maximilian
name: Walk, Steffen
name: Zwick, Julia
Publisher: name: TUHH Universitätsbibliothek
Year: 2020
Subjects: subject: HOOU
subject: Jahresbericht
classificationCode: 000
subject: Allgemeines, Wissenschaft
classificationCode: 370
subject: Erziehung, Schul- und Bildungswesen

description: Der Jahresbericht gibt einen Überblick über die Aktivitäten der Hamburg Open Online University (HOOU) an der Technischen Universität Hamburg im Jahr 2020. Hier werden einerseits die Entwicklungen in den Handlungsfeldern sowie öffentlichkeitswirksame Maßnahmen (Veröffentlichungen und Veranstaltungen) und andererseits die Entwicklungen in den einzelnen Projekten dargestellt.
description: The annual report depicts the activities of the Hamburg Open Online University (HOOU) at the University of Technology Hamburg for the year 2020. Therein, the status quo as well as the current development within the various fields of action are being portrayed while also showcasing publications and events undertaken by the HOOU@TUHH. Furthermore, the progress of the individual projects is described.
Surface functionalization enhanced magnetism in SnO_2 nanoparticles and its correlation to photoluminescence properties
Creators: name: Bonu, Venkataramana
name: Das, Arindam
name: Sardar, Manas
name: Dhara, Sandip
name: Tyagi, Ashok Kumar
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: High value of magnetic moment 0.08 emu/g at room temperature for SnO_2 nanoparticles (NPs) was observed. Surface functionalization with octadecyltrichlorosilane (OTS) enhanced the saturation magnetic moment of NPs to an anomalously high value of 0.187 emu/g by altering the electronic configuration on NPs surface. Surface functionalization also suppressed photoluminescence (PL) peaks arising from oxygen defects around 2 eV and caused an increase in the intensities of two peaks near violet region (2.6 - 3 eV). PL studies under uniform external magnetic field enriched understanding of the role of OTS. Both OTS and external magnetic field significantly modulated the luminescence spectra, by altering the surface electronic structure of NPs. Extra spins on the surface of SnO2 NPs created by the surface functionalization process and their influence on resultant magnetic moment and luminescence properties are discussed in details.
description: 8 pages, 7 figures, journal
Distributed Query Answering for Large Data Series Collections
Creators: name: Chatzakis, Manos
name: Fatourou, Panagiota
name: Kosmas, Eleftherios
name: Palpanas, Themis
Publisher: name: Zenodo
Year: 2022
Subjects: data series, distributed systems, distributed data series procesing, exact similarity search

description: This poster has been presented at the poster session of the 4th Summit on Gender Equality in Computing, 2022. It presents preliminary results on how to efficiently answer exact similarity search queries on a modern distributed setting which encompasses multiple nodes with many cores each. The presented algorithms extend state-of-the-art concurrent exact similarity search approaches to work on top of a distributed system with multiple nodes.
Meiotic versus mitotic recombination: Two different routes for double-strand break repair: The different functions of meiotic versus mitotic DSB repair are reflected in different pathway usage and different outcomes
Creators: name: Andersen, Sabrina L.
name: Sekelsky, Jeff
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Studies in the yeast Saccharomyces cerevisiae have validated the major features of the double-strand break repair (DSBR) model as an accurate representation of the pathway through which meiotic crossovers are produced. This success has led to this model being invoked to explain double-strand break (DSB) repair in other contexts. However, most non-crossover recombinants generated during S. cerevisiae meiosis do not arise via a DSBR pathway. Furthermore, and it is becoming increasing clear that DSBR is a minor pathway for recombinational repair of DSBs that occur in mitotically proliferating cells; rather, the synthesis-dependent strand annealing (SDSA) model appears to describe mitotic DSB repair more accurately. Fundamental dissimilarities between meiotic and mitotic recombination are not unexpected, since meiotic recombination serves a very different purpose (accurate chromosome segregation, which requires crossovers) than mitotic recombination (repair of DNA damage, which typically generates non-crossovers).
title: Radioprotection Campaign and Radioprotection Wallet: Educational Strategies that Reduce Children's Excessive Exposure to Radiological Exams.
Creators: name: Bernardo, Monica
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Radioprotection / Radiation dose
subject: Paediatric
subject: Professional issues
subject: CT
subject: Digital radiography
subject: Radiation safety
subject: Education
subject: Education and training
subject: Patterns of Care
subject: Quality assurance

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To demonstrate that The Image Gently ® radioprotection program (1) is applicable to practice and effective in other countries, particularly in...
From promotion to management: The wide impact of bacteria on cancer and its treatment: Prospects & Overviews
Creators: name: Perez-Chanona, Ernesto
name: Jobin, Christian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: In humans, the intestine is the major reservoir of microbes. Although the intestinal microbial community exists in a state of homeostasis called eubiosis, environmental and genetics factors can lead to microbial perturbation or dysbiosis, a state associated with various pathologies including inflammatory bowel diseases (IBD) and colorectal cancer (CRC). Dysbiotic microbiota is thought to contribute to the initiation and progression of CRC. At the opposite end of the spectrum, two recently published studies in Science reveal that the microbiota is essential for chemotherapeutic drug efficacy, suggesting a beneficial microbial function in cancer management. The dichotomy between the beneficial and detrimental roles of the microbiota during cancer initiation, progression and treatment emphasize the interwoven relationship between bacteria and cancer. Moreover, these findings suggest that the microbiota could be considered as a therapeutic target, not only at the level of cancer prevention, but also during management, i.e. by enhancing the efficacy of chemotherapeutics.
Efficacy of surface-generated nitric oxide against Candida albicans adhesion and biofilm formation
Creators: name: Nutz, Steven T.
name: Privett, Benjamin J.
name: Schoenfisch, Mark H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: This report details the efficacy of nitric oxide (NO)-releasing xerogel surfaces composed of N-(6-aminohexyl)aminopropyl trimethoxysilane (AHAP3) and isobutyltrimethoxysilane (BTMOS) against Candida albicans adhesion, viability, and biofilm formation. A parallel plate flow cell assay was used to examine the effect of NO on planktonic fungal cells. Nitric oxide fluxes as low as 14 pmol cm−2 s−1 were sufficient to reduce fungal adhesion by ~49% over controls after 90 min. By utilizing a fluorescence live/dead assay and replicate plating, NO flux was determined to reduce fungal viability in a dose dependent manner. The formation of C. albicans biofilms on NO-releasing xerogel-coated silicon rubber (SiR) coupons was impeded when compared to control (non-NO-releasing) and bare SiR surfaces. Finally, the synergistic efficacy of NO and silver sulfadiazine against C. albicans adhered fungal cells and biofilms is reported with increased killing and biofilm inhibition over NO alone.
Disruption and eradication of P. aeruginosa biofilms using nitric oxide-releasing chitosan oligosaccharides
Creators: name: Dixon, Graham A.
name: Schoenfisch, Mark H.
name: Reighard, Katelyn P.
name: Hill, David B.
name: Worley, Brittany V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Biofilm disruption and eradication were investigated as a function of nitric oxide- (NO) releasing chitosan oligosaccharide dose with results compared to control (ie non-NO-releasing) chitosan oligosaccharides and tobramycin. Quantification of biofilm expansion/contraction and multiple-particle tracking microrheology were used to assess the structural integrity of the biofilm before and after antibacterial treatment. While tobramycin had no effect on the physical properties of the biofilm, NO-releasing chitosan oligosaccharides exhibited dose-dependent behavior with biofilm degradation. Control chitosan oligosaccharides increased biofilm elasticity, indicating that the scaffold may mitigate the biofilm disrupting power of nitric oxide somewhat. The results from this study indicate that nitric oxide-releasing chitosan oligosaccharides act as dual-action therapeutics capable of eradicating and physically disrupting P. aeruginosa biofilms.
title: Role of CT colonography (CTC) in a regional colorectal cancer (CRC) screening programme: preliminary results
Creators: name: Coppola, Francesca
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Colon
subject: Gastrointestinal tract
subject: Oncology
subject: CAD
subject: CT
subject: Colonography CT
subject: Screening
subject: Computer Applications-Virtual imaging
subject: Cancer
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: CTColonography (CTC) is highly sensitive and minimally invasive alternative modality to optical colonoscopy (OC). The aim of this study is to present the preliminary results of CTC in a regional CRC screening...
Application of Permutation Group Theory in Reversible Logic Synthesis
Creators: name: Zakablukov, Dmitry V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Emerging Technologies (cs.ET)
subject: FOS: Computer and information sciences

description: The paper discusses various applications of permutation group theory in the synthesis of reversible logic circuits consisting of Toffoli gates with negative control lines. An asymptotically optimal synthesis algorithm for circuits consisting of gates from the NCT library is described. An algorithm for gate complexity reduction, based on equivalent replacements of gates compositions, is introduced. A new approach for combining a group-theory-based synthesis algorithm with a Reed-Muller-spectra-based synthesis algorithm is described. Experimental results are presented to show that the proposed synthesis techniques allow a reduction in input lines count, gate complexity or quantum cost of reversible circuits for various benchmark functions.
description: In English, 15 pages, 2 figures, 7 tables. Proceeding of the RC 2016 conference
Methods for a quantitative evaluation of odd-even staggering effects
Creators: name: Olmi, Alessandro
name: Piantelli, Silvia
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Odd-even effects, also known as "staggering" effects, are a common feature observed in the yield distributions of fragments produced in different types of nuclear reactions. We review old methods, and we propose new ones, for a quantitative estimation of these effects as a function of proton or neutron number of the reaction products. All methods are compared on the basis of Monte Carlo simulations. We find that some are not well suited for the task, the most reliable ones being those based either on a non-linear fit with a properly oscillating function or on a third (or fourth) finite difference approach. In any case, high statistic is of paramount importance to avoid that spurious structures appear just because of statistical fluctuations in the data and of strong correlations among the yields of neighboring fragments.
description: 16 pages, 9 figures - Revised version, mainly with an expanded sect. 2 about smoothing methods (three more methods are presented and an appendix on relevant aspects of the finite-differences formalism is added); results are shown also for the simulations with the three additional methods. Some more references are added. Conclusions are unchanged
iFoldRNA: three-dimensional RNA structure prediction and folding
Creators: name: Sharma, Shantanu
name: Dokholyan, Nikolay V.
name: Ding, Feng
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Summary: Three-dimensional RNA structure prediction and folding is of significant interest in the biological research community. Here, we present iFoldRNA, a novel web-based methodology for RNA structure prediction with near atomic resolution accuracy and analysis of RNA folding thermodynamics. iFoldRNA rapidly explores RNA conformations using discrete molecular dynamics simulations of input RNA sequences. Starting from simplified linear-chain conformations, RNA molecules (<50 nt) fold to native-like structures within half an hour of simulation, facilitating rapid RNA structure prediction. All-atom reconstruction of energetically stable conformations generates iFoldRNA predicted RNA structures. The predicted RNA structures are within 2–5 Å root mean squre deviations (RMSDs) from corresponding experimentally derived structures. RNA folding parameters including specific heat, contact maps, simulation trajectories, gyration radii, RMSDs from native state, fraction of native-like contacts are accessible from iFoldRNA. We expect iFoldRNA will serve as a useful resource for RNA structure prediction and folding thermodynamic analyses.
Incorporating sequence information into the scoring function: a hidden Markov model for improved peptide identification
Creators: name: Khatun, Jainab
name: Hamlett, Eric
name: Giddings, Morgan C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The identification of peptides by tandem mass spectrometry (MS/MS) is a central method of proteomics research, but due to the complexity of MS/MS data and the large databases searched, the accuracy of peptide identification algorithms remains limited. To improve the accuracy of identification we applied a machine-learning approach using a hidden Markov model (HMM) to capture the complex and often subtle links between a peptide sequence and its MS/MS spectrum.
CUSTEIO ABC (ACTIVITY BASED COSTING) NA AFERIÇÃO DE CUSTOS LOGÍSTICOS DE ARMAZÉM PRIMÁRIO
Creators: name: Cervi, Ricardo Ghantous
name: Barreto, Gabrielle
name: Oliveira, Paulo André De
name: Rodrigues, Sergio Augusto
Publisher: name: Revista de Informação Contábil
Year: 2023
Subjects: Custos

description: Este estudo teve como objetivo aferir os custos logísticos dos processos internos de um armazém primário por meio do método Activity Based Costing (ABC). Foi realizado um estudo observacional com abordagem quantitativa de caráter exploratório e descritivo, com a adoção do método de custeio ABC. O processamento dos dados, obtidos por meio de fontes primárias em uma empresa multinacional, foi decomposto em três partes principais: identificação de atividades e recursos; relações de causa versus efeito entre recursos e atividades para definição dos direcionadores de custos; e desagregação dos custos por recurso e por atividade. A atividade de maior impacto financeiro para a empresa foi a armazenagem, com R$ 43.721,00 por mês, representando 42,1% dos custos totais das atividades, seguidos por 36,5% de expedição, 15,9% de recebimento e 5,5% de inspeção. Essas informações contribuem para a priorização de medidas gerenciais a partir das análises dos custos por recurso e por atividade.
description: Revista de Informação Contábil, v. 16 (2022): Publicação contínua
SISTEMA DE INFORMAÇÃO DE CUSTOS DO PODER EXECUTIVO DE SANTA CATARINA: PROCESSO DE DESENVOLVIMENTO E PERSPECTIVAS FUTURAS
Creators: name: Ferreira, Gilceu
name: Meincheim, Graziela Luiza
name: Raupp, Fabiano Maury
Publisher: name: Revista de Informação Contábil
Year: 2023

description: O presente artigo analisa o processo de desenvolvimento do Sistema de Informação de Custos do Poder Executivo Catarinense (SIC/SC), destacando as principais etapas percorridas até o estágio atual e as perspectivas futuras para uso pleno desse sistema pelos órgãos e entidades estaduais. A pesquisa é qualitativa, descritiva e categorizada como estudo de caso. Para a coleta e a análise de dados, utilizou-se pesquisa documental e participante, além de entrevistas semiestruturadas com atores envolvidos no processo, realizando-se análise documental. Os resultados da pesquisa analisaram o desenvolvimento do SIC/SC, iniciado em 2012 até o estágio atual, que se encontra em fase de implantação em três entidades estaduais. As perspectivas retrataram futuras melhorias e evoluções do SIC/SC, treinamentos aos usuários, divulgação das informações de custos por meio de ferramentas tecnológicas, como um Portal de Custos, fomento à cultura da utilização da informação de custos pelos usuários, assim como a regulamentação do sistema de custos através de decreto estadual.
description: Revista de Informação Contábil, v. 16 (2022): Publicação contínua
A novel method for large tree visualization
Creators: name: Guan, Xiaojun
name: Kaufmann, William
name: Heard, Jeff
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Summary: Many genomic and proteomic analyses generate as a result a tree of genes or proteins. These trees are often large (containing tens of thousands of nodes and edges), and need a visualization tool to fully display all the information contained in the tree. Clustering analysis can be performed on these trees to obtain clusters of proteins, and we need an efficient way to visualize the clustering results. We present a novel tree visualization tool to help with such analyses.Availability: http://www2.renci.org/~jeff/software/bin/win32/ProteinVis-2.1.6-win32.zipContact: jeff@renci.org; xguan@renci.org
RX J0440.9+4431: another supercritical X-ray pulsar
Creators: name: Salganik, Alexander
name: Tsygankov, Sergey S.
name: Doroshenko, Victor
name: Molkov, Sergey V.
name: Lutovinov, Alexander A.
name: Mushtukov, Alexander A.
name: Poutanen, Juri
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: In the beginning of 2023 the Be transient X-ray pulsar RX J0440.9+4431 underwent a fist-ever giant outburst observed from the source peaking in the beginning of February and reaching peak luminosity of $\sim 4.3\times10^{37}$ erg s$^{-1}$. Here we present the results of a detailed spectral and temporal study of the source based on NuSTAR, INTEGRAL, Swift, and NICER observations performed during this period and covering wide range of energies and luminosities. We find that both the pulse profile shape and spectral hardness change abruptly around $\sim2.8\times10^{37}$ erg s$^{-1}$, which we associate with a transition to super-critical accretion regime and erection of the accretion column. The observed pulsed fraction decreases gradually with energy up to 20 keV (with a local minimum around fluorescence iron line), which is unusual for an X-ray pulsar, and then rises rapidly at higher energies with the pulsations significantly detected up to $\sim120$ keV. The broadband energy spectra of RX J0440.9+4431 at different luminosity states can be approximated with a two-hump model with peaks at energies of about 10-20 and 50-70 keV previously suggested for other pulsars without additional features. In particular an absorption feature around 30 keV previously reported and interpreted as a cyclotron line in the literature appears to be absent when using this model, so the question regarding the magnetic field strength of the neutron star remains open. Instead, we attempted to estimate field using several indirect methods and conclude that all of them point to a relatively strong field of around $B\sim 10^{13}$ G.
description: 11 pages, 10 figures, 2 tables. Submitted to MNRAS
The Next Generation Virgo Cluster Survey. XII. Stellar Populations and Kinematics of Compact, Low-Mass Early-Type Galaxies from Gemini GMOS-IFU Spectroscopy
Creators: name: Guerou, Adrien
name: Emsellem, Eric
name: McDermid, Richard M.
name: Cote, Patrick
name: Ferrarese, Laura
name: Blakeslee, John P.
name: Durrell, Patrick R.
name: MacArthur, Lauren A.
name: Peng, Eric W.
name: Cuillandre, Jean-Charles
name: Gwyn, Stephen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present Gemini GMOS-IFU data of eight compact low-mass early-type galaxies (ETGs) in the Virgo cluster. We analyse their stellar kinematics, stellar population, and present two-dimensional maps of these properties covering the central 5"x 7" region. We find a large variety of kinematics: from non- to highly-rotating objects, often associated with underlying disky isophotes revealed by deep images from the Next Generation Virgo Cluster Survey. In half of our objects, we find a centrally-concentrated younger and more metal-rich stellar population. We analyze the specific stellar angular momentum through the lambdaR parameter and find six fast-rotators and two slow-rotators, one having a thin counter-rotating disk. We compare the local galaxy density and stellar populations of our objects with those of 39 more extended low-mass Virgo ETGs from the SMAKCED survey and 260 massive ($M>10^{10}$\Msun) ETGs from the A3D sample. The compact low-mass ETGs in our sample are located in high density regions, often close to a massive galaxy and have, on average, older and more metal-rich stellar populations than less compact low-mass galaxies. We find that the stellar population parameters follow lines of constant velocity dispersion in the mass-size plane, smoothly extending the comparable trends found for massive ETGs. Our study supports a scenario where low-mass compact ETGs have experienced long-lived interactions with their environment, including ram-pressure stripping and gravitational tidal forces, that may be responsible for their compact nature.
description: Accepted in ApJ, 19 pages, 10 figures
Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance
Creators: name: Xin, Fuxiao
name: Li, Meng
name: Nephew, Kenneth P.
name: Liu, Yunlong
name: Kim, Sun
name: Thomson, Michael
name: Fan, Meiyun
name: Balch, Curt
name: Hammond, Scott M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Motivation: Recent evidence shows significant involvement of microRNAs (miRNAs) in the initiation and progression of numerous cancers; however, the role of these in tumor drug resistance remains unknown.
Sub-Ohmic to super-Ohmic crossover behavior in nonequilibrium quantum systems with electron-phonon interactions
Creators: name: Wilner, Eli Y.
name: Wang, Haobin
name: Thoss, Michael
name: Rabani, Eran
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The transition from weakly damped coherent motion to localization in the context of the spin-boson model has been the subject of numerous studies with distinct behavior depending on the form of the phonon-bath spectral density, $J\left(ω\right)\proptoω^{s}$. Sub-Ohmic ($s<1$) and Ohmic ($s=1$) spectral densities show a clear localization transition at zero temperature and zero bias, while for super-Ohmic ($s>1$) spectral densities this transition disappears. In this work, we consider the influence of the phonon-bath spectral density on the \emph{nonequilibrium} dynamics of a quantum dot with electron-phonon interactions described by the extended Holstein model. Using the reduced density matrix formalism combined with the multi-layer multiconfiguration time-dependent Hartree approach, we investigate the dynamic response, the time scales for relaxation, as well as the existence of multiple long-lived solutions as the system-bath coupling changes from the sub- to the super-Ohmic cases. Bistability is shown to diminish for increasing powers of $s$ similar to the spin-boson case. However, the physical mechanism and the dependence on the model parameters such as the typical bath frequency $ω_{c}$ and the polaron shift $λ$ are rather distinct.
description: 10 pages, 6 figures
A domain-level DNA strand displacement reaction enumerator allowing arbitrary non-pseudoknotted secondary structures
Creators: name: Grun, Casey
name: Sarma, Karthik
name: Wolfe, Brian
name: Shin, Seung Woo
name: Winfree, Erik
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Emerging Technologies (cs.ET)
subject: Molecular Networks (q-bio.MN)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: DNA strand displacement systems have proven themselves to be fertile substrates for the design of programmable molecular machinery and circuitry. Domain-level reaction enumerators provide the foundations for molecular programming languages by formalizing DNA strand displacement mechanisms and modeling interactions at the "domain" level - one level of abstraction above models that explicitly describe DNA strand sequences. Unfortunately, the most-developed models currently only treat pseudo-linear DNA structures, while many systems being experimentally and theoretically pursued exploit a much broader range of secondary structure configurations. Here, we describe a new domain-level reaction enumerator that can handle arbitrary non-pseudoknotted secondary structures and reaction mechanisms including association and dissociation, 3-way and 4-way branch migration, and direct as well as remote toehold activation. To avoid polymerization that is inherent when considering general structures, we employ a time-scale separation technique that holds in the limit of low concentrations. This also allows us to "condense" the detailed reactions by eliminating fast transients, with provable guarantees of correctness for the set of reactions and their kinetics. We hope that the new reaction enumerator will be used in new molecular programming languages, compilers, and tools for analysis and verification that treat a wider variety of mechanisms of interest to experimental and theoretical work. We have implemented this enumerator in Python, and it is included in the DyNAMiC Workbench Integrated Development Environment.
description: Accepted for oral presentation at Verification of Engineered Molecular Devices and Programs (VEMDP), July 17, 2014, Vienna, Austria. 29 pages, conference version. (Revised and expanded journal version is in preparation.)
FastMap: Fast eQTL mapping in homozygous populations
Creators: name: Rusyn, Ivan
name: Nobel, Andrew B.
name: Gatti, Daniel M.
name: Wright, Fred A.
name: Shabalin, Andrey A.
name: Lam, Tieu Chong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Motivation: Gene expression Quantitative Trait Locus (eQTL) mapping measures the association between transcript expression and genotype in order to find genomic locations likely to regulate transcript expression. The availability of both gene expression and high-density genotype data has improved our ability to perform eQTL mapping in inbred mouse and other homozygous populations. However, existing eQTL mapping software does not scale well when the number of transcripts and markers are on the order of 105 and 105–106, respectively.Results: We propose a new method, FastMap, for fast and efficient eQTL mapping in homozygous inbred populations with binary allele calls. FastMap exploits the discrete nature and structure of the measured single nucleotide polymorphisms (SNPs). In particular, SNPs are organized into a Hamming distance-based tree that minimizes the number of arithmetic operations required to calculate the association of a SNP by making use of the association of its parent SNP in the tree. FastMap's tree can be used to perform both single marker mapping and haplotype association mapping over an m-SNP window. These performance enhancements also permit permutation-based significance testing.Availability: The FastMap program and source code are available at the website: http://cebc.unc.edu/fastmap86.htmlContact: iir@unc.edu; nobel@email.unc.eduSupplementary information: Supplementary data are available at Bioinformatics online.
Soft Power and Tourism: A Study of Chinese Outbound Tourism to Africa
Creators: name: Chen, Yu-Wen
name: Duggan, Niall
Publisher: name: Journal of China and International Relations
Year: 2016

description: The increase of Sino-African interactions in trade, aid and investments has attracted Chinese tourists to Africa. The Beijing Action Plan of the Forum on China-Africa Cooperation (FOCAC) outlines China’s cultural diplomacy in Africa, delineating a number of areas of cultural cooperation: education; press, publishing and media; and tourism and people-to-people exchange programs in academia and think tanks among young people, women and athletes. Though scholars of International relations (IR) have detected that tourism is one way of manifesting soft power, they do not feel comfortable nor ready to place the promotion of tourism into standard IR discourse. This is in contrast to scholars of tourism studies who have recognized the political nature of China's outbound tourism, particularly to less-developed areas such as Africa. In this paper, we have argued that the Chinese government uses outbound tourism to perform its perceived relationship with African countries; that is, Beijing aspires to be seen as a benign rising power willing to help weaker countries develop and establish harmonious ties. It is hard to separate the economic and cultural functions of outbound tourism, each of which reinforces the other, although not without limits. We find that not all African countries’ national tourism policies are capable of, or willing to prioritize, attracting Chinese tourists. Moreover, we find that South Africa is most active in working with public relations companies in China to promote South Africa as a tourist destination.
description: Journal of China and International Relations, Vol 4 No 1 (2016)
"QAYNOQ NUQTALAR"DA JURNALIST XAVFSIZLIGI MASALASI
Creators: name: Шираева, Эътибор
Publisher: name: Zenodo
Year: 2023

description: "Qaynoq nuqtalar"da jurnalist xavfsizligi nihoyatda dolzarb va uni himoyalash masalasi anchayin mushkul. Xalqaro gumanitar huquq va huquqni muhofaza qiluvchi organlar jurnalist hayoti xavfsizligi bo'yicha ish olib borsada, urush hududlarida har daqiqada biror daydi o'q oqibatida halok bo'lish hech gap emas. Shuning jurnalistning har jihatdan tayyorgarligi va "qaynoq nuqtalar"da faoliyat yuritishi bo'yicha xalqaro tashkilotlar tomonidan berilgan tavsiya va yo'riqlar keltiriladi. Amaliy tajribalar asosidagi tavsiyalar tahlil qilinadi.
The Morse index of Chaperon's generating families
Creators: name: Mazzucchelli, Marco
Publisher: name: arXiv
Year: 2015
Subjects: subject: Symplectic Geometry (math.SG)
subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 58E05, 70H05, 34C25

description: This is an expository paper devoted to the Morse index of Chaperon's generating families of Hamiltonian diffeomorphisms. After reviewing the construction of such generating families, we present Bott's iteration theory in this setting: we study how the Morse index of a critical point corresponding to an iterated periodic orbit depends on the order of iteration of the orbit. We also investigate the precise dependence of the Morse index from the choice of the generating family associated to a given Hamiltonian diffeomorphism, which will allow to see the Morse index as a Maslov index for the linearized Hamiltonian flow in the symplectic group. We will conclude the survey with a proof that the classical Morse index from Tonelli Lagrangian dynamics coincides with the Maslov index.
description: 45 pages, Version 2: minor corrections to Example 3.5
Randomness generation based on spontaneous emissions of lasers
Creators: name: Zhou, Hongyi
name: Yuan, Xiao
name: Ma, Xiongfeng
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Random number plays a key role in information science, especially in cryptography. Based on the probabilistic nature of quantum mechanics, quantum random number generators can produce genuine randomness. In particular, random numbers can be produced from laser phase fluctuations with a very high speed, typically in the Gbps regime. In this work, by developing a physical model, we investigate the origin of the randomness in quantum random number generators based on laser phase fluctuations. We show how the randomness essentially stems from spontaneous emissions. The laser phase fluctuation can be quantitatively evaluated from basic principles and also qualitatively explained by the Brownian motion model. After taking account of practical device precision, we show that the randomness generation speed is limited by the finite resolution of detection devices. Our result also provides the optimal experiment design in order to achieve the maximum generation speed.
description: 8 pages, 8 figures
DRESS: Scalable Multi-Node Data Series Indexing
Creators: name: Chatzakis, Manos
name: Fatourou, Panagiota
name: Kosmas, Eleftherios
name: Palpanas, Themis
name: Papadospiridakis, Manolis
Publisher: name: Zenodo
Year: 2022
Subjects: data series, concurrent computing, similarity search, distributed processing, multi-node system

description: This poster has been presented in the 4th Summit on Gender Equality in Computing, 2022. It studies the problem of efficiently constructing data series indexes on multi-node environments, while still exploiting the computation power of the multiple cores supported on each node.
Suppression of Surface-Originated Gate-Lag by a Dual-Channel AlN/GaN HEMT Architecture
Creators: name: Deen, David A.
name: Storm, David F.
name: Katzer, D. Scott
name: Bass, Robert
name: Meyer, David J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A dual-channel AlN/GaN high electron mobility transistor (HEMT) architecture is demonstrated that leverages ultra-thin epitaxial layers to suppress surface-state related gate lag. Two high-density two-dimensional electron gas (2DEG) channels are utilized in an AlN/GaN/AlN/GaN heterostructure wherein the top 2DEG serves as a quasi-equipotential that screens potential fluctuations resulting from surface and interface trapped charge. The bottom channel serves as the transistor's modulated channel. Dual-channel AlN/GaN heterostructures were grown by molecular beam epitaxy on free-standing HVPE GaN substrates where 300 nm long recessed and non-recessed gate HEMTs were fabricated. The recessed-gate HEMT demonstrated a gate lag ratio (GLR) of 0.88 with no collapse in drain current and supporting small signal metrics $f_t/f_{max}$ of 27/46 GHz. These performance results are contrasted with the non-recessed gate dual-channel HEMT with a GLR of 0.74 and 82 mA/mm current collapse with $f_t/f_{max}$ of 48/60 GHz.
description: 6 pages, 6 figures, in review at IEEE Transactions on Electron Devices
Hydrodynamic mixing of accretion disk outflows in collapsars: implications for r-process signatures
Creators: name: Barnes, Jennifer
name: Duffell, Paul C.
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The astrophysical environments capable of triggering heavy-element synthesis via rapid neutron capture (the r-process) remain uncertain. While binary neutron star mergers (NSMs) are known to forge r-process elements, certain rare supernovae (SNe) have been theorized to supplement, or even dominate, r-production by NSMs. However, the most direct evidence for such SNe, unusual reddening of the emission caused by the high opacities of r-process elements, has not been observed. Recent work identified the distribution of r-process material within the SN ejecta as a key predictor of the ease with which signals associated with r-process enrichment could be discerned. Though this distribution results from hydrodynamic processes at play during the SN explosion, thus far it has been treated only in a parameterized way. We use hydrodynamic simulations to model how disk winds, the alleged locus of r-production in rare SNe, mix with initially r-process-free ejecta. We study mixing as a function of the wind mass and duration and of the initial SN explosion energy, and find that it increases with the first two of these and decreases with the third. This suggests that SNe accompanying the longest long-duration gamma-ray bursts are promising places to search for signs of r-process enrichment. We use semianalytic radiation transport to connect hydrodynamics to electromagnetic observables, allowing us to assess the mixing level at which the presence of r-process material can be diagnosed from SN light curves. Analytic arguments constructed atop this foundation imply that a wind-driven r-process-enriched SN model is unlikely to explain standard energetic SNe.
description: V2 accepted to ApJ. Absolute banger. The authors encourage the widest possible adoption of the term "collapsaR-process.''
Identification of differential gene pathways with principal component analysis
Creators: name: Ma, Shuangge
name: Kosorok, Michael R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Motivation: Development of high-throughput technology makes it possible to measure expressions of thousands of genes simultaneously. Genes have the inherent pathway structure, where pathways are composed of multiple genes with coordinated biological functions. It is of great interest to identify differential gene pathways that are associated with the variations of phenotypes.
Speckle Interferometry with CMOS Detector
Creators: name: Strakhov, I. A.
name: Safonov, B. S.
name: Cheryasov, D. V.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: In 2022 we carried out an upgrade of the speckle polarimeter (SPP) -- the facility instrument of the 2.5-m telescope of the Caucasian Observatory of the SAI MSU. During the overhaul, CMOS Hamamatsu ORCA-Quest qCMOS C15550-20UP was installed as the main detector, some drawback of the previous version of the instrument were eliminated. In this paper, we present a description of the instrument, as well as study some features of the CMOS detector and ways to take them into account in speckle interferometric processing. Quantitative comparison of CMOS and EMCCD in the context of speckle interferometry is performed using numerical simulation of the detection process. Speckle interferometric observations of 25 young variable stars are given as an example of astronomical result. It was found that BM And is a binary system with a separation of 273 mas. The variability of the system is dominated by the brightness variations of the main component. A binary system was also found in NSV 16694 (TYC 120-876-1). The separation of this system is 202 mas.
description: 24 pages, 27 figures. Minor style differences with respect to version accepted to Astrophys. Bull. V. 78, no. 2
SAFEGUI: resampling-based tests of categorical significance in gene expression data made easy
Creators: name: Rusyn, Ivan
name: Wright, Fred A.
name: Gatti, Daniel M.
name: Barry, William T.
name: Sypa, Myroslav
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Summary: A large number of websites and applications perform significance testing for gene categories/pathways in microarray data. Many of these packages fail to account for expression correlation between transcripts, with a resultant inflation in Type I error. Array permutation and other resampling-based approaches have been proposed as solutions to this problem. SAFEGUI provides a user-friendly graphical interface for the assessment of categorical significance in microarray studies, while properly accounting for the effects of correlations among genes. SAFEGUI incorporates both permutation and more recently proposed bootstrap algorithms that are demonstrated to be more powerful in detecting differential expression across categories of genes.Availability: http://cebc.unc.edu/software/Contact: fwright@bios.unc.edu; dmgatti@email.unc.edu
Effect of ensemble generalization on the highest-occupied Kohn-Sham eigenvalue
Creators: name: Kraisler, Eli
name: Schmidt, Tobias
name: Kümmel, Stephan
name: Kronik, Leeor
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: There are several approximations to the exchange-correlation functional in density-functional theory that accurately predict total energy-related properties of many-electron systems, such as binding energies, bond lengths, and crystal structures. Other approximations are designed to describe potential-related processes, such as charge transfer and photoemission. However, the development of a functional which can serve the two purposes simultaneously is a long-standing challenge. Trying to address it, we employ in the current work the ensemble generalization procedure proposed in Phys. Rev. Lett. 110, 126403 (2013). Focusing on the prediction of the ionization potential via the highest occupied Kohn-Sham eigenvalue, we examine a variety of exchange-correlation approximations: the local spin-density approximation, semi-local generalized gradient approximations, and global and local hybrid functionals. Results for a test set of 26 diatomic molecules and single atoms are presented. We find that the aforementioned ensemble generalization systematically improves the prediction of the ionization potential, for various systems and exchange-correlation functionals, without compromising the accuracy of total energy-related properties. We specifically examine hybrid functionals. These depend on a parameter controlling the ratio of semi-local to non-local functional components. The ionization potential obtained with ensemble-generalized functionals is found to depend only weakly on the parameter value, contrary to common experience with non-generalized hybrids, thus eliminating one aspect of the so-called `parameter dilemma' of hybrid functionals.
A probabilistic framework for aligning paired-end RNA-seq data
Creators: name: Chiang, Derek Y.
name: Prins, Jan F.
name: Hu, Yin
name: He, Xiaping
name: Wang, Kai
name: Liu, Jinze
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Motivation: The RNA-seq paired-end read (PER) protocol samples transcript fragments longer than the sequencing capability of today's technology by sequencing just the two ends of each fragment. Deep sampling of the transcriptome using the PER protocol presents the opportunity to reconstruct the unsequenced portion of each transcript fragment using end reads from overlapping PERs, guided by the expected length of the fragment.
Matlab Based Model of MOSA Network in Power systems
Creators: name: E N, ganesh
Publisher: name: figshare
Year: 2022
Subjects: subject: 90699 Electrical and Electronic Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This paper investigates the operation of SPD-type metal oxide surge arresters (MOSA) in low voltage networks TN and IT at sources of overvoltages due to direct attacks via building lightning arresters (external lightning protection systems). This research is based on Matlab Simulink.
China and Latin America Relations: The Win-Win Rhetoric
Creators: name: Bernal-Meza, Raúl
Publisher: name: Journal of China and International Relations
Year: 2016

description: The text analyzes the economic relations between China and Latin America in the context of the capitalist world system. It is argued that as a world power, China has developed a network of economic, trade and financial relations with other economies around the core, the semi-periphery and periphery of the system. The analysis explains the nature of the structure of economic relations between China and Latin America, which is part of China's periphery. The structure of the relationship between China and Latin America is a function of China's development and not of its periphery. In other words, the relationship serves Chinese interests through the unequal relationship in which China exports manufactured goods and high value-added products and imports basic products and commodities from Latin America. To justify this unequal relationship, Beijing argues that both partners are part of the developing world and that the trade structure between the two parties is of mutual benefit. It is what we call "win-win rhetoric". The paper argues that this explanation serves China as a means to hide a bilateral relationship that has a distinct North-South structure and that serves China's own interests. The text further argues that the relationship between the two parties serves China's interests as a world power. Thus, China has a utilitarian relationship with Latin America.
description: Journal of China and International Relations, Special Issue 2016