cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Search for dark matter particles in W$^+$W$^-$ events with transverse momentum imbalance in proton-proton collisions at $\sqrt{s}$ = 13 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for dark matter particles is performed using events with a pair of W bosons and large missing transverse momentum. Candidate events are selected by requiring one or two leptons ($\ell =$ electrons or muons). The analysis is based on proton-proton collision data collected at a center-of-mass energy of 13 TeV by the CMS experiment at the LHC and corresponding to an integrated luminosity of 138 fb$^{-1}$. No significant excess over the expected standard model background is observed in the $\ellν$qq and 2$\ell$2$ν$ final states of the W$^+$W$^-$ boson pair. Limits are set on dark matter production in the context of a simplified dark Higgs model, with a dark Higgs boson mass above the W$^+$W$^-$ mass threshold. The dark matter phase space is probed in the mass range 100-300 GeV, extending the scope of previous searches. Current exclusion limits are improved in the range of dark Higgs masses from 160 to 250 GeV, for a dark matter mass of 200 GeV.
description: Replaced with the published version. Added the journal reference and the DOI. All the figures and tables can be found at http://cms-results.web.cern.ch/cms-results/public-results/publications/EXO-21-012 (CMS Public Pages)
BindingDB Entry 12170: N-heteroaryl indazole derivatives as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Leucine-rich repeat serine/threonine-protein kinase 2, Merck Sharp & Dohme, Affinity

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2, Uniprot Q5S007
Flat band effects on the ground-state BCS-BEC crossover in atomic Fermi gases in a quasi-two-dimensional Lieb lattice
Creators: name: Deng, Hao
name: Li, Chuping
name: Wu, Yuxuan
name: Sun, Lin
name: Chen, Qijin
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: The ground-state superfluid behavior of ultracold atomic Fermi gases with a short-range attractive interaction in a quasi-two-dimensional Lieb lattice is studied using BCS mean-field theory, within the context of BCS-BEC crossover. We find that the flat band leads to nontrivial exotic effects. As the Fermi level enters the flat band, both the pairing gap and the in-plane superfluid density exhibit an unusual power law as a function of interaction, with strongly enhanced quantum geometric effects, in addition to a dramatic increase of compressibility as the interaction approaches the BCS limit. As the Fermi level crosses the van Hove singularities, the character of pairing changes from particle-like to hole-like or vice versa. We present the computed phase diagram, in which a pair density wave state emerges at high densities with relatively strong interaction strength.
description: 9 pages, 6 figures in color
Health service use among migrants in the German national cohort : the role of birth region and language skills
Creators: name: Wiessner, Christian
name: Licaj, Sara
name: Klein, Jens
name: Bohn, Barbara
name: Brand, Tilman
name: Castell, Stefanie
name: Führer, Amand-Gabriel
name: Harth, Volker
name: Heier, Margit
name: Heise, Jana-Kristin
name: Holleczek, Bernd
name: Mikolajczyk, Rafael
name: [Und Viele Weitere]
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Objective: To compare health service use (HSU) between migrants and non-migrants in Germany. Methods: Using data from the population-based German National Cohort (NAKO), we compared the HSU of general practitioners, medical specialists, and psychologists/psychiatrists between six migrant groups of different origins with the utilization of non-migrants. A latent profile analysis (LPA) with a subsequent multinomial regression analysis was conducted to characterize the HSU of different groups. Additionally, separate regression models were calculated. Both analyses aimed to estimate the direct effect of migration background on HSU. Results: In the LPA, the migrant groups showed no relevant differences compared to non-migrants regarding HSU. In separate analyses, general practitioners and medical specialists were used comparably to slightly more often by first-generation migrants from Eastern Europe, Turkey, and resettlers. In contrast, the use of psychologists/psychiatrists was substantially lower among those groups. Second-generation migrants and migrants from Western countries showed no differences in their HSU compared to non-migrants. Conclusion: We observed a low mental HSU among specific migrant groups in Germany. This indicates the existence of barriers among those groups that need to be addressed.
I: Grimston Ware: examples of early Neolithic pottery from north and east Cheshire
Creators: name: Mullin, D
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 77, 1-7
description: Early Neolithic pottery recovered during excavations at the medieval village of Norton, Cheshire during the 1970s is published for the first time and placed within a wider regional context, alongside similar pottery from Abbey Green, Chester and Beeston Castle. The depositional context of the material is also considered.
BindingDB Entry 12169: Hsp90β selective inhibitors
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Heat shock protein HSP 90-alpha and Heat shock protein HSP 90-beta, University of Notre Dame Du Lac, Affinity

description: Small molecule binding data for protein Heat shock protein HSP 90-alpha and Heat shock protein HSP 90-beta, Uniprot P07900 and P08238
BindingDB Entry 12168: CYCLIN INHIBITORS
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Cyclin-A2/Cyclin-dependent kinase 2, Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B, and Cyclin-dependent kinase 2/G1/S-specific cyclin-E1, Circle Pharma, Affinity

description: Small molecule binding data for protein Cyclin-A2/Cyclin-dependent kinase 2, Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B, and Cyclin-dependent kinase 2/G1/S-specific cyclin-E1, Uniprot P15206, P20248, P24864, P24941, and Q9DGD3
Notes on the Overchurch runic stone
Creators: name: Dallow, Wilfrid
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 3, 185-191
description: A sculptured stone with a runic inscription, possibly dating to the 7th century, was discovered amongst the material from a church at Upton on the Wirral, taken down in 1887. The inscription is discussed in the previous article in this volume (pp 178-84). The present article outlines the history of an earlier church at Overchurch from which the building materials for the Upton church were taken, and describes the process by which the stone and its inscription were studied. One possible scenario describes a historical context in which the stone may have originated. LD
SHAROF  RASHIDOV  - VATANNING  FIDOYI FARZANDI
Creators: name: Radjapboyeva, X.M.
Publisher: name: Zenodo
Year: 2024

description: O`zbekiston mustaqillikka erishganimizdan so`ng, ko`plab xalqimizni quvontiradigan o`zgarishlar ro`y berdi. Vatanning ziyoli vakillari, o`tmish tarixning yorqin vakillari qoralangan edi .Ijod ahli, siyosiy arboblar, jadidlar shu jumladandir. Tamg`a va og`riq bo`lgan tuhmatlardan ozod bo`lishi orzu edi.Istiqlol sabab bizning tariximiz zulmatdan yorug`lik tomon chiqdi ,desak yanglishmagan bo`lamiz. Bizning zaminda xalq dardini o`zining dardi deb bilgan bir qancha fidoyi,vatanparvar, mard o`g`lonlari juda ko`p bo`lgan. Jumladan, Sharof Rashidov  ham Vatanning elparvar farzandi bo`lgan.U Vatan  ravnaqi uchun ulkan hissa qo`shgan, hurmat e`zozga loyiq bo`lgan fidoyi inson edi .Umrini xalqini turmushini,hayotini yaxshilash uchun yashadi,bor kuchi hamda sog`ligini ertangi kun taraqqiyoti ,farovon hayotiga bag`ishladi.
BindingDB Entry 12165: COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Adenosine receptor A2a, Chong Kun Dang Pharmaceutical, Affinity

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274 and X5DNB4
Global Chemical Transport on Hot Jupiters: Insights from 2D VULCAN photochemical model
Creators: name: Tsai, Shang-Min
name: Parmentier, Vivien
name: Mendonça, João M.
name: Tan, Xianyu
name: Deitrick, Russell
name: Hammond, Mark
name: Savel, Arjun B.
name: Zhang, Xi
name: Pierrehumbert, Raymond T.
name: Schwieterman, Edward W.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The atmospheric dynamics of tidally-locked hot Jupiters is characterized by strong equatorial winds. Understanding the interaction between global circulation and chemistry is crucial in atmospheric studies and interpreting observations. Two-dimensional (2D) photochemical transport models shed light on how the atmospheric composition depends on circulation. In this paper, we introduce the 2D photochemical (horizontal and vertical) transport model, VULCAN 2D, which improves on the pseudo-2D approaches by allowing for non-uniform zonal winds. We extensively validate our VULCAN 2D with analytical solutions and benchmark comparisons. Applications to HD 189733 b and HD 209458 b reveal a transition in mixing regimes: horizontal transport predominates below $\sim$0.1 mbar while vertical mixing is more important at higher altitudes above 0.1 mbar. Motivated by the previously inferred carbon-rich atmosphere, we find that HD 209458 b with super-solar carbon-to-oxygen ratio (C/O) exhibits pronounced C$_2$H$_4$ absorption on the morning limb but not on the evening limb, owing to horizontal transport from the nightside. We discuss when a pseudo-2D approach is a valid assumption and its inherent limitations. Finally, we demonstrate the effect of horizontal transport in transmission observations and its impact on the morning-evening limb asymmetry with synthetic spectra, highlighting the need to consider global transport when interpreting exoplanet atmospheres.
description: 19 pages, 20 figures, published in ApJ
Tunable optical properties and the role of defects on the carrier lifetimes of Cs3Sb2I9 synthesized in various solvents
Creators: name: Neguse, Samuel M.
name: Yoon, Songhak
name: Frebel, Alexander
name: Jöckel, Dennis M.
name: Widenmeyer, Marc
name: Lange, Stefan
name: Rosspeintner, Arnulf
name: Ebbinghaus, Stefan
name: Hagendorf, Christian
name: Balke, Benjamin
name: Weidenkaff, Anke
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 540

description: Pb-free halide perovskites have recently attracted immense attention due to the number of advantages in their optical and electronic properties. However, tuning the optical bandgap with minimized amounts of point defects is a particularly challenging task in photovoltaics. It is pivotal to clearly understand the detailed relationship between the bandgap change with defect generation and charge carrier lifetime. In this study, Cs3Sb2I9 crystals are synthesized by varied choice of solvents, namely, γ-butyrolactone, a mixture of dimethylformamide and dimethyl sulfoxide, and hydroiodic acid. Although the same principles of decreasing solubility and crystallization are applied, Cs3Sb2I9 crystals with different size and shape in microscopic and macroscopic scale are obtained during heating and cooling of the solution. The synthesized crystals are investigated using a combination of different spectroscopies including Raman, UV–visible, and time-resolved photoluminescence. In the results, it is suggested that there is a strong relationship between Urbach energy and the lifetime of charge carriers. In this research, readily applicable practical principles and examples of how to control the defects for the advancement in Pb-free perovskite photovoltaics are provided.
Chester: - the evolution and adaptation of its landscape
Creators: name: Mason, D J P
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 59, 14-23
description: Information from excavations is used to attempt a reconstruction of the original configuration of the landscape, including the course of the river; to analyse the influence of the major physical features on the siting of the Roman fortress and the medieval city walls, and to study the accumulation and distribution of the deposits of two millennia of human occupation. Au(adp)
Identification, synthesis and strategy for minimization of potential impurities in the synthesis of suvorexant
Creators: name: Lv, Xunlei
name: Pan, Jing
name: Liu, Weiyuan
name: Meng, Xue
name: Chen, Liang
name: Zhou, Ting
name: Lin, Kuaile
name: Ye, Deyong
name: Zhou, Weicheng
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Eight process-related impurities in the synthesis of suvorexant were identified, while six of them were described for the first time. In order to get the references for the process optimization and quality control of API, the eight compounds were synthesized. According to the possible formation pathways, a modified synthesis and the strategy for impurity control in the corresponding reactions were established.
II: Brook House Farm, Bruen Stapleford: excavation of a first millennium BC settlement
Creators: name: Bonner, David
name: Carruthers, Wendy J
name: Fairburn, Neil
name: Matthews, K J
name: Ward, M
name: Morris, Ernest
name: Gale, G R
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 77, 9-57
description: Excavations revealed a settlement consisting of six possible domestic structures along with other features dating from the Middle Bronze Age to the Late Iron Age. Radiocarbon determinations suggest that the settlement was in use between c. 1000 cal BC and c. 800 cal BC and between c. 400 cal BC and c. 100 cal AD. Includes separately authored reports on:
Incorporating a-priori information in deep learning models for quantitative susceptibility mapping via adaptive convolution
Creators: name: Graf, Simon
name: Wohlgemuth, Walter A.
name: Deistung, Andreas
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Quantitative susceptibility mapping (QSM) has attracted considerable interest for tissue characterization (e.g., iron and calcium accumulation, myelination, venous vasculature) in the human brain and relies on extensive data processing of gradient-echo MRI phase images. While deep learning-based field-to-susceptibility inversion has shown great potential, the acquisition parameters applied in clinical settings such as image resolution or image orientation with respect to the magnetic field have not been fully accounted for. Furthermore, the lack of comprehensive training data covering a wide range of acquisition parameters further limits the current QSM deep learning approaches. Here, we propose the integration of a priori information of imaging parameters into convolutional neural networks with our approach, adaptive convolution, that learns the mapping between the additional presented information (acquisition parameters) and the changes in the phase images associated with these varying acquisition parameters. By associating a-priori information with the network parameters itself, the optimal set of convolution weights is selected based on data-specific attributes, leading to generalizability towards changes in acquisition parameters. Moreover, we demonstrate the feasibility of pre-training on synthetic data and transfer learning to clinical brain data to achieve substantial improvements in the computation of susceptibility maps. The adaptive convolution 3D U-Net demonstrated generalizability in acquisition parameters on synthetic and in-vivo data and outperformed models lacking adaptive convolution or transfer learning. Further experiments demonstrate the impact of the side information on the adaptive model and assessed susceptibility map computation on simulated pathologic data sets and measured phase data.
Multicrystalline, highly oriented thick-film silicon from reduction of soda-lime glass
Creators: name: Schall, Ingrid
name: Ebbinghaus, Stefan
name: Strelow, Christian
name: Peiner, Erwin
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 540

description: The study describes synthesis and characterization of > 10 µm thick multicrystalline (mc), highly oriented, p-doped silicon layers by aluminothermic reduction of low-cost soda-lime glass. X-ray diffraction shows a highly preferred (111)-orientation and excellent crystallinity. Low compressive stress and very good crystallinity are confirmed by the peak position and width of the Raman LO-phonon line, approaching the one of bulk single-crystalline wafer material. Due to strong bonding to the glass substrate layer, spalling is not observed. A conductive aluminum-rich oxide layer is formed underneath the silicon, serving as an electrical back-contact for electronic devices. Using secondary ion mass spectrometry very low concentrations of 1014–1015 cm−3 of impurities are found originating from the soda-lime glass with an iron content below the detection limit. Furthermore, a plateau-like, very homogenous Al concentration of ≈4 × 1018 cm−3 over a thickness of ≈10 µm is found, which corresponds to the solubility of Al in Si at the process temperature. Complete electronic activation within the plateau region is confirmed by carrier concentration measurements using electrochemical capacitance–voltage profiling and Raman spectroscopy. Hole concentrations in the range of few 1018 cm−3 are beneficial for the p-type base material of full-emitter cell mc-silicon photovoltaic devices.
Probing the Schroedinger-Newton equation in a Stern-Gerlach interferometer
Creators: name: Aguiar, Gabriel H. S.
name: Matsas, George E. A.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Explaining the behavior of macroscopic objects from the point of view of the quantum paradigm has challenged the scientific community for a century today. A mechanism of gravitational self-interaction, governed by the so-called Schroedinger-Newton equation, is among the proposals that aim to shed some light on it. Despite all efforts, this mechanism has been proven difficult to probe. Here, we consider a simple Stern-Gerlach-like experiment to try it out. The Schroedinger-Newton equation can be analytically solved under certain proper conditions, and a dephasing effect induced by the gravitational self-interacting potential can be calculated.
description: Final version (6 pages, 5 figures)
III: Birch Heath, Tarporley: excavation of a rural Romano-British settlement
Creators: name: Gale, Rowena M O
name: Bonner, David
name: Carruthers, Wendy J
name: Dunn, Gillian
name: Fairburn, Neil
name: Ward, M
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 77, 59-114
description: Excavation revealed a small Romano-British rural settlement whose inhabitants practised mixed agriculture. The settlement consisted of three roundhouses, a possible rectangular building and boundary ditches and flourished in the second century AD. A fourth building associated with ironworking was dated to the post-Roman period. Radiocarbon dates were obtained of 70--350 cal AD for one of the settlement structures and of 590--720 cal AD for material from the fourth building. Includes reports on:
Toward Local Madelung Mechanics in Spacetime
Creators: name: Waegell, Mordecai
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Classical Physics (physics.class-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: It has recently been shown that relativistic quantum theory leads to a local interpretation of quantum mechanics wherein the universal wavefunction in configuration space is entirely replaced with an ensemble of local fluid equations in spacetime. For want of a fully relativistic quantum fluid treatment, we develop a model using the nonrelativistic Madelung equations, and obtain conditions for them to be local in spacetime. Every particle in the Madelung fluid is equally real, and has a definite position, momentum, kinetic energy, and potential energy. These are obtained by defining quantum momentum and kinetic energy densities for the fluid and separating the momentum into average and symmetric parts, and kinetic energy into classical kinetic and quantum potential parts. The two types of momentum naturally give rise to a single classical kinetic energy density, which contains the expected kinetic energy, even for stationary states, and we define the reduced quantum potential as the remaining part of the quantum kinetic energy density. We treat the quantum potential as a novel mode of internal energy storage within the fluid particles, which explains most of the nonclassical behavior of the Madelung fluid. For example, we show that in tunneling phenomena the quantum potential negates the barrier so that nothing prevents the fluid from flowing through. We show how energy flows and transforms in this model, and that enabling local conservation of energy requires defining a quantum potential energy current that flows through the fluid rather than only flowing with it. The nonrelativistic treatment generally contains singularities in the velocity field, which undermines the goal of local dynamics, but we expect a proper relativistic treatment will bound the fluid particle velocities at $c$.
description: 17 pages main, 5 pages appendix with 4 figures, 2 supplementary animations
A living topochemical ring-opening polymerization of achiral amino acid N-carboxy-anhydrides in single crystals
Creators: name: Rohmer, Matthias
name: Ebbinghaus, Stefan
name: Busse, Karsten
name: Radicke, Julian
name: Kressler, Jörg
name: Binder, Wolfgang H.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 540

description: A living topochemical ring-opening polymerization (ROP) of achiral amino-acid N-carboxyanhydrides (NCAs) is reported. Single crystals of the NCAs of α-aminoisobutyric acid (Aib) and 1-aminocyclohexanecarboxylic acid (ACHC) were grown, allowing a ring-opening polymerization macroscopically induced by amines. The single crystals could be polymerized at temperatures from 25–50 °C after physically contacting the amine-based initiator with the crystals. Topochemical polymerization of the crystals was proven by MALDI-ToF MS and XRD, generating polymers with chain lengths of up to 40 units and a complete affixation of the initiating amine at the polymer's head. Due to the proper alignment of the reacting groups in the crystal, longer polymer chains with improved purities can be reached, as chain-transfer is reduced as compared to solution polymerization. Simple purification of the polymers can be achieved by separation of the unreacted NCA via dispersion in acetonitrile. Overall, this method enables the preparation of polymers with higher chain length and purities at mild conditions, finally demonstrating a crystal-based ring opening polymerization.
BindingDB Entry 12162: BENZOTHIAZOLE AND QUINOLINE DERIVATIVES FOR USE IN TREATING KAWASAKI DISEASE
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Alpha-protein kinase 1, Shanghai Yao Yuan Biotechnology Co., Affinity

description: Small molecule binding data for protein Alpha-protein kinase 1, Uniprot Q96QP1
Mapping the role of oral cavity physiological factors into the viscoelastic model of denture adhesives for numerical implementation
Creators: name: Narayanan Ramakrishnan, Anantha
name: Röhrle, Röhrle
name: Ludtka, Christopher
name: Koehler, Josephine
name: Kiesow, Andreas
name: Schwan, Stefan
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Physiological parameters of the oral cavity have a profound impact on any restorative solutions designed for edentulous patients including denture adhesives. This study aims to mathematically quantify the influence of three such variables, namely: the temperature, pH, and the swelling of such adhesives under the influence of saliva on its mechanical behavior. The mathematical quantification is further aimed to implement a material model for such adhesives which considers the impact of such physiological factors. The denture adhesive is experimentally investigated by means of rheological steady state frequency sweep tests to obtain the relaxation spectrum of the material. The relaxation behavior is measured for a wide range of oral cavity temperatures and pH. Also, the adhesive is hydrated and upon swelling to different levels again tested to understand the impact of swelling on the mechanical behavior. The experimentally measured continuous relaxation spectrum is modeled as a viscoelastic material using a discrete set of points based on the Prony series discretization technique. The relaxation spectrums for various temperatures are compared and the possibility of a time-temperature superposition is explored for the model. Similarly, the measured values of Storage and loss modulus are investigated to understand the role of pH and swelling. The results in this study clearly indicated a horizontal shift in the relaxation behavior with increase in temperature. And hence, the time-temperature shift factor was calculated for the adhesive. The relaxation spectrum also showed a strong correlation with swelling of the adhesive and the pH. The influence of these two parameters were captured into the model based on the relaxation time parameter in the Prony series approach. Based on this study the impact of these parameters could be appreciated on the performance and mechanical behavior of denture adhesives and implemented into a Prony series based viscoelastic material model which can be used with numerical simulations.
BindingDB Entry 12161: POLYCYCLIC COMPOUND AND APPLICATION THEREOF
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Cytochrome P450 3A4, Lysine-specific histone demethylase 1A, and Potassium voltage-gated channel subfamily H member 2, Sichuan Huiyu Pharmaceutical Co., Affinity

description: Small molecule binding data for protein Cytochrome P450 3A4, Lysine-specific histone demethylase 1A, and Potassium voltage-gated channel subfamily H member 2, Uniprot O60341, P08684, and Q12809
A drug safety briefing (II) in transplantation from real-world individual pharmacotherapy management to prevent patient and graft from polypharmacy risks at the very earliest stage
Creators: name: Wolf, Ursula
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 615

description: For early and long-term patient and graft survival, drug therapy in solid organ and hematopoietic stem cell transplantation inevitably involves polypharmacy in patients with widely varying and even abruptly changing conditions. In this second part, relevant medication briefing is provided, in addition to the scores defined in the previously published first part on the design of the Individual Pharmacotherapy Management (IPM). The focus is on the growing spectrum of contemporary polypharmacy in transplant patients, including early and long-term follow-up medications. 1. Unlike the available drug–drug interaction (DDI) tables, for the first time, this methodological all-in-one device refers to the entire risks, including contraindications, special warnings, adverse drug reactions (ADRs), and DDIs. The selection of 65 common critical drugs results from 10 years of daily IPM with real-world evidence from more than 60,800 IPM inpatient and outpatient medication analyses. It includes immunosuppressants and typical critical antimicrobials, analgesics, antihypertensives, oral anticoagulants, antiarrhythmics, antilipids, antidepressants, antipsychotics, antipropulsives, antiemetics, propulsives, proton pump inhibitors (PPIs), sedatives, antineoplastics, and protein kinase inhibitors. As a guide for the attending physician, the drug-related risks are presented in an alphabetical overview based on the Summaries of Product Characteristics (SmPCs) and the literature. 2. Further briefing refers to own proven clinical measures to manage unavoidable drug-related high-risk situations. Drug-induced injuries to the vulnerable graft and the immunosuppressed comorbid patient require such standardized, intensive IPM and the comprehensive preventive briefing toolset to optimize the outcomes in the polypharmacy setting.
Chester Cathedral: the recent work in the cloisters and refectory
Creators: name: Barber, E
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 21, 169-183
description: Article describing repair and renovation works to elements of Chester Cathedral, including the removal of some 550 tons of soil and 80 tons of broken stone from the pockets of the groining in the cloisters and other places. The broken stones included fragments of all periods from Norman times onwards. During the works evidence of Early English architecture was noted, and some faulty building work of the medieval period was exposed. LD
BindingDB Entry 12160: Salt of LSD1 inhibitor and a polymorph thereof
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Lysine-specific histone demethylase 1A, Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Affinity

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
Implications of Filial Responsibility for Latino Adolescents' Psychological and Social Adjustment: A Resilience Perspective
Creators: name: Alvarez-Jimenez, Anabel
Publisher: name: Georgia State University
Year: 2008

description: Filial responsibility was examined among a sample of Latino adolescents using both cross-sectional and longitudinal data in order to understand both the positive and negative impact different patterns of responsibilities may have on psychological adjustment and interpersonal competence. This study attempted to move beyond a deficit-based approach to also understanding the mechanisms that allow youth to thrive despite exposure to difficult situations. Furthermore, birth order, gender, and immigration age were examined as potential moderators. Cluster analysis identified four groups based on adolescents? self-reported levels of responsibility, including, fair balanced, unfair overwhelmed, fair low, and unfair low. Results found that adolescents who perceived their responsibilities as fair reported better levels of psychological adjustment. In addition, adolescents in the fair low cluster reported lower levels of interpersonal competence than all other cluster groups. Lastly, birth order was found to moderate the relation between cluster group and positive psychological adjustment. Specifically, oldest children in the unfair overwhelmed cluster reported higher levels of positive psychological adjustment than oldest children in the unfair low cluster.
BindingDB Entry 12159: Methods
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: 5-hydroxytryptamine receptor 2A, D(1A) dopamine receptor, D(2) dopamine receptor, Mu-type opioid receptor, and Sodium-dependent serotonin transporter, Intra-Cellular Therapies, Affinity

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, D(1A) dopamine receptor, D(2) dopamine receptor, Mu-type opioid receptor, and Sodium-dependent serotonin transporter, Uniprot A0A024R3C5, P14416, P21728, P28223, P31645, and P35372
Additional file 1 of Reliability and validity of the Chinese version of the LMC Skills, Confidence & Preparedness Index (SCPI) in patients with type 2 diabetes
Creators: name: Wang, Ximin
name: Lyu, Weibo
name: Aronson, Ronnie
name: Li, Aihua
name: Lu, Gendi
name: Xu, Weijin
name: Cao, Yang
name: Yu, Ying
name: Wang, Liting
name: Lin, Huiting
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: Additional file 1. Process of cross-cultural adaptation & General information of experts & Modified content after interviewing.
PT-symmetry enabled spintronic thermal diodes and logic gates
Creators: name: Wang, Xi-Guang
name: Guo, Guang-Hua
name: Berakdar, Jamal
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 530

description: Devices for performing computation and logic operations with low-energy consumption are of key importance for environmentally friendly data processing and information technology. Here, a design for magnetic elements that use excess heat to perform logic operations is presented. The basic information channel is coupled non-conductive magnetic stripes with a normal metal spacer. The thermal information signal is embodied in magnetic excitations and it can be transported, locally enhanced, and controllably steered by virtue of charge current pulses in the spacer. Functionality of essential thermal logic gates is demonstrated by material-specific simulations. The operation principle takes advantage of the special material architecture with a balanced gain/loss mechanism for magnetic excitation which renders the circuit parity-time symmetric with exceptional points tunable by the current strength in the spacer. Heat flow at these points can be enhanced, be non-reciprocal, or may oscillate between the information channels enabling controlled thermal diode and thermal gate operations. The findings point to a new route for exploiting heat for useful work on the nanoscale.
Private Variable-Length Coding with Zero Leakage
Creators: name: Zamani, Amirreza
name: Oechtering, Tobias J.
name: Gündüz, Deniz
name: Skoglund, Mikael
Publisher: name: arXiv
Year: 2023
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: A private compression design problem is studied, where an encoder observes useful data $Y$, wishes to compress it using variable length code and communicates it through an unsecured channel. Since $Y$ is correlated with private attribute $X$, the encoder uses a private compression mechanism to design encoded message $\cal C$ and sends it over the channel. An adversary is assumed to have access to the output of the encoder, i.e., $\cal C$, and tries to estimate $X$. Furthermore, it is assumed that both encoder and decoder have access to a shared secret key $W$. The design goal is to encode message $\cal C$ with minimum possible average length that satisfies a perfect privacy constraint. To do so we first consider two different privacy mechanism design problems and find upper bounds on the entropy of the optimizers by solving a linear program. We use the obtained optimizers to design $\cal C$. In two cases we strengthen the existing bounds: 1. $|\mathcal{X}|\geq |\mathcal{Y}|$; 2. The realization of $(X,Y)$ follows a specific joint distribution. In particular, considering the second case we use two-part construction coding to achieve the upper bounds. Furthermore, in a numerical example we study the obtained bounds and show that they can improve the existing results.
description: arXiv admin note: text overlap with arXiv:2306.13184, arXiv:2309.09034, arXiv:2211.15525, arXiv:2310.19122
Adaptive Functioning following Pediatric Traumatic Injury: The Relationship between Parental Stress, Parenting Styles, and Child Functional Outcomes
Creators: name: Micklewright, Jackie
Publisher: name: Georgia State University
Year: 2009

description: Moderate and severe pediatric traumatic brain injuries (TBI) are associated with significant familial stress and child cognitive and adaptive sequelae (Taylor et al., 1999). Research has demonstrated a relationship between familial stress and resources and child recovery of functioning following TBI (Taylor et al., 1999). We built on these findings by examining authoritarian parenting values and styles as a mediator of the relationship between parental stress and child adaptive outcomes 12-36 months following TBI or orthopedic injury (ORTHO). Participants were 21 children/adolescents with traumatic brain injuries and 23 with orthopedic injuries and one of their parents/guardians. Parents completed measures of demographics, parental stress, parenting values and styles, and child adaptive functioning. Child participants completed brief demographic questionnaires and intelligence screeners. Moderation was examined using hierarchical multiple regression. Mediation and moderated mediation were examined using bootstrapping tests of the indirect effect of parental stress on child adaptive functioning. After controlling for family insurance status, higher levels of parental stress were associated with reduced child adaptive functioning in the TBI group but not the ORTHO group. An examination of the mediational analyses revealed that higher levels of parental stress were associated with a greater reliance on authoritarian parenting styles, which was associated with reduced overall adaptive functioning and daily living skills across the two injury groups. Therefore, across groups, the relationship between parental stress and child overall adaptive functioning and daily living skills was found to be partially mediated by an authoritarian parenting style. Moderated mediation results revealed the presence of a significant interaction and 95% confidence interval on the socialization domain and indicated that the relationship between authoritarian parenting styles and child adaptive social skills differed significantly between the two groups. Our findings suggest a relationship between parental stress, authoritarian parenting styles, and child adaptive functioning in the 12-36 months following pediatric traumatic injury. Future research should explore the association among these, as well as other potentially mediating variables, both within and between the two groups with the goal of further elucidating the relationship between familial/environmental variables and child adaptive functioning following traumatic brain and orthopedic injury.
BindingDB Entry 12158: COMPOUNDS AND METHODS FOR TREATING HYPERKALEMIA
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: 11-beta-hydroxysteroid dehydrogenase type 2, Ardelyx, Affinity

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase type 2, Uniprot P80365
BindingDB Entry 12157: HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Tyrosine-protein kinase JAK1, Chiesi Farmaceutici, Affinity

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1, Uniprot P23458
Fast ellipsoidal conformal and quasi-conformal parameterization of genus-0 closed surfaces
Creators: name: Choi, Gary P. T.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computational Geometry (cs.CG)
subject: Graphics (cs.GR)
subject: Complex Variables (math.CV)
subject: Differential Geometry (math.DG)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Surface parameterization plays a fundamental role in many science and engineering problems. In particular, as genus-0 closed surfaces are topologically equivalent to a sphere, many spherical parameterization methods have been developed over the past few decades. However, in practice, mapping a genus-0 closed surface onto a sphere may result in a large distortion due to their geometric difference. In this work, we propose a new framework for computing ellipsoidal conformal and quasi-conformal parameterizations of genus-0 closed surfaces, in which the target parameter domain is an ellipsoid instead of a sphere. By combining simple conformal transformations with different types of quasi-conformal mappings, we can easily achieve a large variety of ellipsoidal parameterizations with their bijectivity guaranteed by quasi-conformal theory. Numerical experiments are presented to demonstrate the effectiveness of the proposed framework.
Let's Play a Trick:  Children's Understanding of Mind within Social Interaction
Creators: name: Nelson, Pamela
Publisher: name: Georgia State University
Year: 2009

description: Despite numerous studies of the development of theory of mind, how children express their understanding of mind in less structured, play settings has gone largely unstudied. Many developmental accounts, regardless of disagreement on other theoretical issues, agree that the child?s engagement within social contexts is crucial to the development of understanding of mind. Our goals were to collect a detailed account of how children use their understanding of mind and how mothers align their support to the child?s capabilities within social interactions. In this longitudinal study, typically developing preschoolers (N = 52) engaged in a hiding game with their mothers in a semi-structured play setting when the children were 42-, 54-, and 66-months old. Aspects of children?s understanding of mind were rated including understanding of knowledge access, deception, false belief, and emotional response to false belief, as well as, affective charge and engagement with the task. Mothers? utterances were coded for various characteristics, particularly role and content. Children?s understanding of mind increased across visits and positively correlated with false belief task performance at the 42- and 54-month visits, rs = .35 and .39, p < .05, but not the 66-month visit, rs = ?.25, p = .10. Children?s enthusiasm was positively related to their understanding of mind at the first and second visits, but not the last. Mothers tailored the content of their utterances to the child?s growing expertise, but whether mothers adjusted the role of their utterances to children?s understanding of mind remains unclear. Observing children?s playful use of their emerging understanding of mind in social interactions allowed for the capture of subtle variations in how children express and caregivers support their understanding.
GRAN-ONCO: "German Research Agenda for Nursing Oncology" : Entwicklung einer Forschungsagenda der onkologischen Pflege in Deutschland
Creators: name: Zilezinski, Max
name: Ritter-Herschbach, Madeleine
name: Jahn, Patrick
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Hintergrund: Die Etablierung von Forschungsprioritäten und Bündelung in einer Agenda dient dazu, die Weiterentwicklung des Forschungsfeldes zu systematisieren. In Deutschland liegt zum aktuellen Zeitpunkt keine Forschungsagenda für die onkologische Pflege vor. Zielstellung: Entwicklung einer Forschungsagenda der onkologischen Pflege im Rahmen eines diskursiven Prozesses unter Berücksichtigung verschiedener Perspektiven der an der Versorgung beteiligten Personengruppen. Methode: Mittels eines Mixed-Methods-Designs wurden Forschungsthemen mithilfe einer systematischen Literaturrecherche identifiziert und anhand einer Online-Befragung sowie einer qualitativen Erhebung im Rahmen von Expertengruppen durch Pflegefachpersonen der onkologischen Pflegepraxis und -forschung priorisiert und ergänzt. Ergebnisse: Die Synthese der Literatur umfasst 29 Veröffentlichungen mit 55 Themen. Auf Grundlage des Survey wurden hieraus 23 Themen als prioritär identifiziert. Aus den Survey-Rückmeldungen (n = 174) und dem Feedback der Expert_innen (n = 15) können folgende Themenbereiche für die Agenda formuliert werden: Krankheits- und therapiebedingte Auswirkungen und die damit einhergehenden Bedürfnisse, Veränderungen, Kommunikation/Information/Beratung und Edukation sowie Fragen nach Lebensqualität und Versorgung am Lebensende. Schlussfolgerung: Erstmals liegt für Deutschland eine Forschungsagenda für die onkologische Pflege vor. Sie ist ein wichtiger Schritt der Professionalisierung und bietet damit eine Orientierung für die wissenschaftliche Weiterentwicklung der Pflege in der Onkologie.
BindingDB Entry 12156: COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Methylcytosine dioxygenase TET2, University of Barcelona, Affinity

description: Small molecule binding data for protein Methylcytosine dioxygenase TET2, Uniprot Q6N021
IV: Legh Oaks Farm, High Legh: the value of sample excavation on two sites of the late prehistoric and Roman periods
Creators: name: Nevell, Michael D
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 77, 115-129
description: Targeted fieldwalking and excavation on two cropmark enclosures allowed an outline chronology to be established. Finds from Enclosure B suggested that this was the earlier site and might date from the late prehistoric period, while material from Enclosure A suggested occupation during the second century AD but perhaps beginning much earlier. The spread of lithic material across the whole of the southern half of the field implies occupation in this area during the last two millennia BC. The survey of the two sites has also demonstrated the value of combining aerial photographic reconnaissance with targetted field survey work on known cropmark sites.