cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: Figure S1. of Adaptation of iCLIP to plants determines the binding landscape of the clock-regulated RNA-binding protein AtGRP7
Creators: name: Meyer, Katja
name: Köster, Tino
name: Nolte, Christine
name: Weinholdt, Claus
name: Lewinski, Martin
name: Grosse, Ivo
name: Staiger, Dorothee
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Infectious Diseases
subject: FOS: Health sciences

description: Monitoring for UV stress upon UV crosslinking. Related to Fig. 1. Figure S2. iCLIP of AtGRP7-GFP. Figure S3. Significant crosslink sites in AtGRP7::GFP (GFP), AtGRP7::AtGRP7 R 49 Q -GFP (RQ), and AtGRP7::AtGRP7-GFP samples. Figure S4. iCLIP crosslink sites on AtGRP7 target transcripts. Related to Fig. 3. Figure S5. Scatterplot of RIP-seq data versus RNA-seq. Figure S6. Clustering of motifs identified by MEME analysis. Related to Fig. 5. Figure S7. iCLIP crosslink sites in the AtGRP7 transcript in comparison to in vitro binding sites. Figure S8. Differentially expressed AtGRP7 targets (DEGs) in plants with altered AtGRP7 level at LL36. Figure S9. Position of the AtGRP7 crosslink sites within the transcripts at LL24. Related to Fig. 2. Figure S10. Candidate binding motifs LL24. Related to Fig. 5. Figure S11. AtGRP7 targets differentially expressed at LL24 in plants with altered AtGRP7 levels. Figure S12. Changes in distribution of the log2 fold changes of genes differentially expressed at LL24 (DEGs) in the grp7-1 8i mutant or AtGRP7-ox plants upon binding to AtGRP7. Related to Fig. 6. Figure S13. Validation of differential alternative splicing of AtGRP7 targets at LL36. Figure S14. Validation of iCLIP or RIP-seq alternative splicing targets by RIP RT-PCR. Figure S15 Validation of differential alternative splicing of AtGRP7 targets at LL24. (PDF 4700 kb)
Inside the Pinelands: A Report by the Pinelands Preservation Alliance, February-March 2008, Vol. 15, No. 3
Creators: name: No Name Supplied
Publisher: name: Pinelands Preservation Alliance (PPA)
Year: 2008

description: This is the bimonthly newsletter of the Pinelands Preservation Alliance (PPA), a nonprofit organization working to protect and preserve the resources of the New Jersey Pinelands.  Articles featured in this edition include: Pinelands Commission Approves Pollution Trading; Letter from the Executive Director; Companies Support Pinelands Preservation; ORV Legislation in 2008; PPA Memberandum: Nancy Buchanan; and Pinelands Calendar of Events.
Ambient Biomonitoring Network: Raritan Water Region, Watershed Management Areas 7, 8, 9 and 10; Round 3 Benthic Macroinvertebrate Data, Volume 1 of 2.
Creators: name: No Name Supplied
Publisher: name: New Jersey Department of Environmental Protection (NJDEP), Water Monitoring and Standards
Year: 2008

description: The Ambient Biomonitoring Network (AMNET) is one of the major ongoing monitoring programs.  This statewide network of over 800 AMNET stations employs sampling and taxonomic analysis of in-stream macroinvertebrate communities to assess the ecological condition at each station.  This report presents the results for the biological monitoring conducted in Raritan Water Region from April to October 2004.  The sampling of this regions marks the third round of data collection for this basin.  Results from this round are compared to those from the same sites sampled in earlier rounds (1994, 1999).
Ambient Biomonitoring Network: Northeast Water Region, Passaic River Drainages, Watershed Management Areas 3, 4, 5 and 6; Round 3 Benthic Macroinvertebrate Data, Volume 1 of 2
Creators: name: No Name Supplied
Publisher: name: New Jersey Department of Environmental Protection (NJDEP), Water Monitoring and Standards
Year: 2008

description: The Ambient Biomonitoring Network (AMNET) is one of the major ongoing monitoring programs.  This statewide network of over 800 AMNET stations employs sampling and taxonomic analysis of in-stream macroinvertebrate communities to assess the ecological condition at each station.  This report presents the results for the biological monitoring conducted in Northeast Water Region from July 2003 to October 2004.  The sampling of this Region marks the third round of data collection for this basin.  Results from round 3 (2003/04) sampling are compared to those from the same sites sampled in the earlier two rounds (1993/94, 1999, respectively).
Clean Ocean Advocate, June 2007
Creators: name: No Name Supplied
Publisher: name: Clean Ocean Action (COA)
Year: 2007

description: The monthly Clean Ocean Advocate newsletter informs citizens about critical ocean pollution issues, important meeting dates, proposed legislation, special events, and other notes of interest. Articles in this issue include: COA Participating Organizations- Asbury Park Fishing Club; Brown Funk Unwelcome Start to Summer Season; Are You Swimming in a Sewer?; Rapid Testing for Bacteria at Beaches Coming to NJ; Finding Solutions To Pollution In and Around Wreck Pond; Dredging Projects Raise Concerns; Actions Against Offshore Drilling; Draft Released on Environmental Impacts of New Energy; Draft Pollution Permit for Monmouth County Bayshore Facility; Welcome to the COA Crew, Michele!; It's Time to "C.O.A.S.T." into Summer; Coastal Creature Feature: Mantis Shrimp; COA'S Beach Party was the "Absolute Ultimate!"; and Recipe for Student Ocean Stewards: Add Water, Sand, Wildlife, and Action. Mix Well.
Development of the Hydroecological Integrity Assessment Process for Determining Environmental Flows for New Jersey Streams
Creators: name: No Name Supplied
Publisher: name: U.S. Geological Survey (USGS)
Year: 2007

description: The U.S. Geological Survey, in cooperation with the New Jersey Department of Enviromental Protection, undertook a project to identify or develop a methodology for establishing environmental-flow standards for regulatory and planning purposes that will sustain stream communities in New Jersey.  This project was called the Ecological Flow Goals (EFG) project.  This report: (1) Describes the initial goal of the EFG project and the approach taken to help achieve that goal; (2) Compares some established environmental flow methods, reviews important stream ecosystem concepts, and examines the critical hydrologic research that represents the framework for the environmental flow process presented herein; (3) Describes the development of a new environmental flow assessment process-the Hydroecological Integrity Assessment Process (HIP). Application of the HIP includes a hydrologic classification of streams in New Jersey, and the development of software tools for classifying unclassified streams (the New Jersey Stream Classification Tool (NJSCT)) and for establishing a baseline (reference) time period, comparing and contrasting past and proposed streamflow alterations, and providing options for setting environmental-flow standards at the reach scale (the New Jersey Hydrologic Assessment Tool (NJHAT)); and (4) Provides example management applications using the NJSCT and the NJHAT for an analysis of land-use changes that are known to alter streamflow, and a series of scenarios of direct surface-water withdrawals from an unregulated stream.
Microglial expression of Hdac1 and Hdac2 is dispensable for experimental autoimmune encephalomyelitis (EAE) progression
Creators: name: Datta, Moumita
name: Hansen, Stefanie M.
name: Staszewski, Ori
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Microglia
subject: Experimental autoimmune encephalomyelitis
subject: Hdac1
subject: Hdac2
subject: Epigenetics
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health

description: Previously, we reported that microglial expression of histone deacetylases 1 and 2 (Hdac1 and Hdac2) is required for microglial maturation and modulates disease progression in a mouse model of Alzheimer’s disease. Here, we analyze the role of microglial expression of Hdac1 and Hdac2 in another disease paradigm, namely experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis. The aim of this study was to ascertain whether microglial expression of these two epigenetic regulators modulates disease progression in the context of autoimmune disease. Hdac1 and Hdac2 were knocked out either individually or in combination using a microglia-specific, tamoxifen-inducible Cre-deleter line (Cx3cr1-CreERT2). The clinical course as well as histopathological changes during EAE were assessed in adult mice lacking microglial expression of these genes. Overall, no differences in disease onset, progression or severity could be detected in mice lacking microglial expression of either one or both of Hdac1 and Hdac2 genes. Similarly, the histopathology showed no differences in lymphocyte or macrophage infiltration or demyelination in either of the analyzed groups. As such, we conclude that unlike in neurodegenerative disease, microglial expression of Hdac1 and Hdac2 does not play a role in EAE.
Summary of the Ground-Water-Level Hydrologic Conditions in New Jersey 2006
Creators: name: No Name Supplied
Publisher: name: U.S. Geological Survey (USGS)
Year: 2007

description: The U.S. Geological Survey (USGS), in cooperation with Federal, State, and local agencies, collects a large amount of data pertaining to the water resources in New Jersey each water year (October 1 to September 30).  This report describes the USGS New Jersey Water Science Center Observation Well Networks. Record low ground-water levels during water year 2006 (October 1, 2005 to September 30, 2006) are listed, and water levels in six selected water-table observation wells and three selected confined wells are shown in hydrographs. The report describes the trends in water levels in various confined aquifers in southern New Jersey and in water-table and fracture rock aquifers throughout the State. Web site addresses to access the data also are included.
Simulation of proposed increases in ground-water withdrawals from the Atlantic City 800-foot sand, New Jersey Coastal Plain
Creators: name: No Name Supplied
Publisher: name: U.S. Department of the Interior, U.S. Geological Survey (USGS)
Year: 2006

description: The confined Atlantic City 800-foot sand and the unconfined Kirkwood-Cohansey aquifer system (surficial aquifer) are major sources of water for southeastern New Jersey. Because of concerns about streamflow depletion resulting from ground-water withdrawals and the potential ecological effects on stream habitat in the area, the focus on withdrawals has been shifted away from the surficial aquifer to the confined Atlantic City 800-foot sand until the effects of increased withdrawals from the surficial aquifer can be investigated. A study was conducted to evaluate the effects of seven proposed increases in ground-water withdrawals from the Atlantic City 800-foot sand and the Kirkwood-Cohansey aquifer system on the Atlantic City 800-foot sand. Full-allocation conditions were simulated to determine conditions that would occur if all wells in the Atlantic City 800-foot sand were pumped at the permitted allocation rate. Output from the full-allocation simulation serves as a baseline for comparison with the output from the seven alternate withdrawal scenarios. The seven scenarios are described along with the incremental and cumulative effects of the increased withdrawals on the water levels in the Atlantic City 800-foot sand and on sources of water to wells. The report describes the models used to simulate the withdrawal scenarios and provides details on the proposed increases in withdrawals. Output from the simulations-water levels, drawdowns, flow budgets, and travel times of particles from saltwater areas to wells-are presented in figures and tables.
Ambient Biomonitoring Network: Northwest Water Region, Upper Delaware and Wallkill River Drainages, Watershed Management Areas 1, 2, and 11; Round 3 Benthic Macroinvertebrate Data, Volume 1 of 2
Creators: name: No Name Supplied
Publisher: name: New Jersey Department of Environmental Protection (NJDEP), Water Monitoring and Standards
Year: 2008

description: The Ambient Biomonitoring Network (AMNET) is one of the major ongoing monitoring programs.  This statewide network of over 800 AMNET stations employs sampling and taxonomic analysis of in-stream macroinvertebrate communities to assess the ecological condition at each station.  This report presents the results for the biological monitoring conducted in Upper Delaware/Northwest Water Region from April 2002 to June 2003.  The sampling of this regions marks the third round of data collection for the AMNET program.  Results from this round are compared to those from the same sites sampled in earlier rounds (1992/93, 1998).
Design patterns for resource-constrained automated Deep-Learning methods
Creators: name: Tuggener, Lukas
name: Amirian, Mohammadreza
name: Benites, Fernando
name: Von Däniken, Pius
name: Gupta, Prakhar
name: Schilling, Frank-Peter
name: Stadelmann, Thilo
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Automated machine learning
subject: Architecture design
subject: Computer vision
subject: Audio processing
subject: Natural language processing
subject: Weakly supervised learning
subject: DDC 004 / Data processing & computer science

description: e present an extensive evaluation of a wide variety of promising design patterns for automated deep-learning (AutoDL) methods, organized according to the problem categories of the 2019 AutoDL challenges, which set the task of optimizing both model accuracy and search efficiency under tight time and computing constraints. We propose structured empirical evaluations as the most promising avenue to obtain design principles for deep-learning systems due to the absence of strong theoretical support. From these evaluations, we distill relevant patterns which give rise to neural network design recommendations. In particular, we establish (a) that very wide fully connected layers learn meaningful features faster; we illustrate (b) how the lack of pretraining in audio processing can be compensated by architecture search; we show (c) that in text processing deep-learning-based methods only pull ahead of traditional methods for short text lengths with less than a thousand characters under tight resource limitations; and lastly we present (d) evidence that in very data- and computing-constrained settings, hyperparameter tuning of more traditional machine-learning methods outperforms deep-learning systems.
Fish IBI Report: 2005 Sampling; Round 2, Year 1 of 5, Volume 1 of 2
Creators: name: No Name Supplied
Publisher: name: New Jersey Department of Environmental Protection, Water Monitoring and Standards Program, Bureau of Freshwater and Biological Monitoring
Year: 2008

description: In order to assess environmental conditions on a larger spacial and temporal scale, the Bureau of Freshwater and Biological Monitoring (BFBM) in 2000 began to suppliment benthic macroinvertebrate monitoring with a new sampling program called the fish index of biotic integrity (FIBI)  A FIBI is an index that measures the health of a stream based on multiple attributes of the resident fish assemblage.  Data provided by the IBI have become another component of the DEP's suite of environmental indicators.  The data help to measure water quality use attainment and the Department's success in attaining the Clean Water Act goal of "fishable" waters. Volume 1 of this report contains a summary of the methods and results of the 2005 IBI sampling.
Fish IBI Report: 2005 Sampling; Round 2, Year 1 of 5, Volume 2 - Site Data Summaries
Creators: name: No Name Supplied
Publisher: name: New Jersey Department of Environmental Protection, Water Monitoring and Standards Program, Bureau of Freshwater and Biological Monitoring
Year: 2008

description: In order to assess environmental conditions on a larger spacial and temporal scale, the Bureau of Freshwater and Biological Monitoring (BFBM) in 2000 began to suppliment benthic macroinvertebrate monitoring with a new sampling program called the fish index of biotic integrity (FIBI)  A FIBI is an index that measures the health of a stream based on multiple attributes of the resident fish assemblage.  Data provided by the IBI have become another component of the DEP's suite of environmental indicators.  The data help to measure water quality use attainment and the Department's success in attaining the Clean Water Act goal of "fishable" waters. Volume 2 is the companion to Volume 1.  Included in volume 2 are individual site location maps, along with site specific aerial photography, habitat assessment sheets, site scoring sheets, and total number of fish species found, along with photographs of each.  Volume 2 is intended for those wanting more site specific details of each site than is provided in Volume 1.
POSSIBILITIES OF BIOREGULATORY CORRECTION IN POST-CONCUSSION SYNDROME
Creators: name: Kapitanchuk, Iryna
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 329999
subject: Other biomedical and clinical sciences not elsewhere classified

description: In the context of the war in Ukraine, the number of cases of mild traumatic brain injury (mTBI) is increasing, which often leads to post-concussion syndrome. Both military and civilians suffer from the consequences of TBI, which has a significant impact on their daily lives and ability to recover.Chronic post-concussion syndrome (CPCS) is characterized by the long-term persistence of neurological symptoms after a TBI. Research by Hall et al. (2005), Roe et al. (2009), and Williams et al. (2010) shows that 40-80% of patients with TBI experience neurological symptoms. CPCS has an impact on the quality of life long after the injury, so injured people need a comprehensive approach to treatment.Considering these factors, CPCS is an important medical and social problem in Ukraine that requires special attention from the health care system, as well as the development of programs for treatment and support of those affected.The article outlines a comprehensive approach to the treatment of a former serviceman based on the technology of complex regulatory therapy of conditions, which involves an assessment of the body's condition with the definition of the basic typical pathological processes (TPP): inflammation, endogenous intoxication, immune, metabolic disorders, autonomic dysregulation and bioregulatory correction of the identified disorders.
Fish IBI Report: 2005 Sampling; Round 2, Year 2 of 5, Volume 1 of 2
Creators: name: No Name Supplied
Publisher: name: New Jersey Department of Environmental Protection, Water Monitoring and Standards Program, Bureau of Freshwater and Biological Monitoring
Year: 2008

description: In order to assess environmental conditions on a larger spacial and temporal scale, the Bureau of Freshwater and Biological Monitoring (BFBM) in 2000 began to suppliment benthic macroinvertebrate monitoring with a new sampling program called the fish index of biotic integrity (FIBI)  A FIBI is an index that measures the health of a stream based on multiple attributes of the resident fish assemblage.  Data provided by the IBI have become another component of the DEP's suite of environmental indicators.  The data help to measure water quality use attainment and the Department's success in attaining the Clean Water Act goal of "fishable" waters. Volume 1 of this report contains a summary of the methods and results of the 2006 IBI sampling.
Long-term effects of asthma medication on asthma symptoms: an application of the targeted maximum likelihood estimation
Creators: name: Veit, Carolin
name: Herrera, Ronald
name: Weinmayr, Gudrun
name: Genuneit, Jon
name: Windstetter, Doris
name: Vogelberg, Christian
name: Von Mutius, Erika
name: Nowak, Dennis
name: Radon, Katja
name: Gerlich, Jessica
name: Weinmann, Tobias
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Adolescents
subject: Asthma
subject: Children
subject: Control medication
subject: Marginal structural models
subject: Targeted-maximum likelihood estimation
subject: DDC 610 / Medicine & health

description: Abstract Background Long-term effectiveness of asthma control medication has been shown in clinical trials but results from observational studies with children and adolescents are lacking. Marginal structural models estimated using targeted maximum likelihood methods are a novel statistiscal approach for such studies as it allows to account for time-varying confounders and time-varying treatment. Therefore, we aimed to calculate the long-term risk of reporting asthma symptoms in relation to control medication use in a real-life setting from childhood to adulthood applying targeted maximum likelihood estimation. Methods In the prospective cohort study SOLAR (Study on Occupational Allergy Risks) we followed a German subsample of 121 asthmatic children (9–11 years old) of the ISAAC II cohort (International Study of Asthma and Allergies in Childhood) until the age of 19 to 24. We obtained self-reported questionnaire data on asthma control medication use at baseline (1995–1996) and first follow-up (2002–2003) as well as self-reported asthma symptoms at baseline, first and second follow-up (2007–2009). Three hypothetical treatment scenarios were defined: early sustained intervention, early unsustained intervention and no treatment at all. We performed longitudinal targeted maximum likelihood estimation combined with Super Learner algorithm to estimate the relative risk (RR) to report asthma symptoms at SOLAR I and SOLAR II in relation to the different hypothetical scenarios. Results A hypothetical intervention of early sustained treatment was associated with a statistically significant risk increment of asthma symptoms at second follow-up when compared to no treatment at all (RR: 1.51, 95% CI: 1.19–1.83) or early unsustained intervention (RR:1.38, 95% CI: 1.11–1.65). Conclusions While we could confirm the tagerted maximum likelihood estimation to be a usable and robust statistical tool, we did not observe a beneficial effect of asthma control medication on asthma symptoms. Because of potential due to the small sample size, lack of data on disease severity and reverse causation our results should, however, be interpreted with caution.
Fish IBI Report: 2005 Sampling; Round 2, Year 2 of 5, Volume 2 of 2
Creators: name: No Name Supplied
Publisher: name: New Jersey Department of Environmental Protection, Water Monitoring and Standards Program, Bureau of Freshwater and Biological Monitoring
Year: 2008

description: In order to assess environmental conditions on a larger spacial and temporal scale, the Bureau of Freshwater and Biological Monitoring (BFBM) in 2000 began to suppliment benthic macroinvertebrate monitoring with a new sampling program called the fish index of biotic integrity (FIBI)  A FIBI is an index that measures the health of a stream based on multiple attributes of the resident fish assemblage.  Data provided by the IBI have become another component of the DEP's suite of environmental indicators.  The data help to measure water quality use attainment and the Department's success in attaining the Clean Water Act goal of "fishable" waters. Volume 2 is the companion to Volume 1.  Included in volume 2 are individual site location maps, along with site specific aerial photography, habitat assessment sheets, site scoring sheets, and total number of fish species found, along with photographs of each.  Volume 2 is intended for those wanting more site specific details of each site than is provided in Volume 1.
Genomic and eco-epidemiological investigations in Uruguay reveal local Chikungunya virus transmission dynamics during its expansion across the Americas in 2023
Creators: name: Burgueño, Analía
name: Giovanetti, Marta
name: Fonseca, Vagner
name: Morel, Noelia
name: Lima, Mauricio
name: Castro, Emerson
name: Guimarães, Natália R.
name: Iani, Felipe C. M.
name: Bormida, Victoria
name: Cortinas, Maria Noel
name: Ramas, Viviana
name: Coppola, Leticia
name: Bento, Ana I.
name: Franco, Leticia
name: Rico, Jairo Mendez
name: Lourenço, José
name: Alcantara, Luiz Carlos Junior
name: Chiparelli, Hector
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Uruguay experienced its first Chikungunya virus outbreak in 2023, resulting in a significant burden to its healthcare system. We conducted analysis based on real-time genomic surveillance (30 novel whole genomes) to offer timely insights into recent local transmission dynamics and eco-epidemiological factors behind its emergence and spread in the country.
Safety and immunogenicity of heterologous boosting with orally administered aerosolized bivalent adenovirus type-5 vectored COVID-19 vaccine and B.1.1.529 variant adenovirus type-5 vectored COVID-19 vaccine in adults 18 years and older: a randomized, double blinded, parallel controlled trial
Creators: name: Xu, Jia-Wei
name: Wang, Bu-Sen
name: Gao, Ping
name: Huang, Hai-Tao
name: Wang, Fei-Yu
name: Qiu, Wei
name: Zhang, Yuan-Yuan
name: Xu, Yu
name: Gou, Jin-Bo
name: Yu, Lin-Ling
name: Liu, Xuan
name: Wang, Rui-Jie
name: Zhu, Tao
name: Hou, Li-Hua
name: Qing-Wang, A..
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Vaccination strategies that can induce a broad spectrum immune response are important to enhance protection against SARS-CoV-2 variants. We conducted a randomized, double-blind and parallel controlled trial to evaluate the safety and immunogenicity of the bivalent (5×1010viral particles) and B.1.1.529 variant (5×1010viral particles) adenovirus type-5 (Ad5) vectored COVID-19 vaccines administrated via inhalation. A total of 451 eligible subjects aged 18 years and older who had been vaccinated with three doses of inactivated COVID-19 vaccines were randomly assigned to inhale one dose of either the B.1.1.529 variant Ad5 vectored COVID-19 vaccine (Ad5-nCoVO-IH group, N=150), bivalent Ad5 vectored COVID-19 vaccine (Ad5-nCoV/O-IH group, N=151), or Ad5 vectored COVID-19 vaccine (5×1010viral particles; Ad5-nCoV-IH group, N=150). Primary safety outcomes including adverse reactions reported by 37 (24.67%) participants in the Ad5-nCoVO-IH group, 28 (18.54%) in the Ad5-nCoV/O-IH group, and 26 (17.33%) in the Ad5-nCoV-IH group with mainly mild to moderate dry mouth, oropharyngeal pain, headache, myalgia, cough, fever and fatigue. No serious adverse events related to the vaccine were reported. All investigational vaccines were immunogenic, with the difference in the GMTs of neutralizing antibodies against Omicron BA.1 was statistically significant between Ad5-nCoV/O-IH (43.70) and Ad5-nCoV-IH (29.25) at 28 days after vaccination (P=0.0238). The seroconversion rates of neutralizing antibodies against BA.1 in Ad5-nCoVO-IH, Ad5-nCoV/O-IH, and Ad5-nCoV-IH groups were 56.00%, 59.60% and 48.67% with no significant difference among the groups. Overall, the investigational vaccines were demonstrated to be safe and well tolerated in adults, and was highly effective in inducing mucosal immunities in addition to humoral and cellular immune responses defending against SARS-CoV-2 variants. Trial registration: Chictr.org identifier: ChiCTR2200063996.
Transmission of Fluoroquinolones Resistance among Multidrug-Resistant Tuberculosis in Shanghai, China: A Retrospective population-based Genomic Epidemiology Study
Creators: name: Li, Minjuan
name: Zhang, Yangyi
name: Wu, Zheyuan
name: Jiang, Yuan
name: Sun, Ruoyao
name: Yang, Jinghui
name: Li, Jing
name: Lin, Honghua
name: Zhang, Rui
name: Jiang, Qi
name: Wang, Lili
name: Wu, Xiaocui
name: Yu, Fangyou
name: Yuan, Jianhui
name: Yang, Chongguang
name: Shen, Xin
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Fluoroquinolones (FQ) are essential for the treatment of multidrug-resistant tuberculosis (MDR-TB). The FQ resistance (FQ-R) rate in MDR-TB in China and its risk factors remain poorly understood. We conducted a retrospective, population-based genomic epidemiology study of MDR-TB patients in Shanghai, China, from 2009 to 2018. A genomic cluster was defined as strains with genetic distances ≤ 12 single nucleotide polymorphisms. The transmitted FQ-R was defined as the same FQ resistance-conferring mutations shared by ≥ 2 strains in a genomic cluster. We used multivariable logistic regression analysis to identify the risk factors for drug resistance. Among the total 850 MDR-TB patients included in the study, 72.8% (619/850) were male, the median age was 39 (interquartile range 28, 55) years, 52.7% (448/850) were migrants, and 34.5% (293/850) were previously treated patients. Most of the MDR-TB strains belong to the Beijing lineage (91.7%, 779/850). Overall, the genotypic resistance rate of FQ was 34.7% (295/850), and 47.1% (139/295) FQ-R patients were in genomic clusters, of which 98 (33.2%, 98/295) were presumed as transmitted FQ-R. Patients with treatment-naïve (aOR = 1.84; 95% CI: 1.09, 3.16), diagnosed in a district-level hospital (aOR = 2.69; 95% CI: 1.56, 4.75), and streptomycin resistance (aOR = 3.69; 95% CI: 1.65, 9.42) were significantly associated with the transmission of FQ-R. In summary, the prevalence of FQ-R among MDR-TB patients was high in Shanghai, and at least one-third were transmitted. Enforced interventions including surveillance of FQ drug susceptibility testing and screening among MDR-TB before initiation of treatment were urgently needed.
Promoting factors and barriers to participation in working life for people with spinal cord injury
Creators: name: Sturm, Christian
name: Bökel, Andrea
name: Korallus, Christoph
name: Geng, Veronika
name: Kalke, Yorck B.
name: Abel, Rainer
name: Kurze, Ines
name: Gutenbrunner, Christoph M.
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Disability studies
subject: Employment
subject: Social security
subject: Spinal cord injuries
subject: Unemployment
subject: DDC 610 / Medicine & health

description: Abstract Background It is still difficult for people with physical impairments to be and remain equally integrated into the labour market. For this reason, the question of occupational activity has explicitly been examined by the German Spinal Cord Injury Survey (GerSCI) in order to identify barriers and facilitators for labour market participation. Methods Cross-sectional explorative observational study. The GerSCI survey is the German part of the International Spinal Cord Injury Survey (InSCI). Using survey data from persons recruited at eight specialised SCI-centres in Germany. Participants: 1.479 persons with Spinal Cord Injury (SCI) aged 18 years and older. Results In a self-disclosure questionnaire, persons with SCI show themselves as a professionally well-educated and highly motivated group with most of them aiming at gainful employment and considering themselves fit for work. Many changeable and non-changeable factors have been found, which showed a high correlation with the return to work after acquired SCI. Conclusion Education and pain belong to the most critical factors and thereby possible approaches to increase the level of employment, which is essential and highly relevant not only for earning money but also for self-confidence and social integration. SCI has many dimensions in itself; support also should be multidimensional. Study results might help to improve participation.
Environmental Stewardship: Moving Beyond Compliance for a Sustainable Future
Creators: name: No Name Supplied
Publisher: name: New Jersey Department of Environmental Protection
Year: 2008

description: As of January 2008, the New Jersey Department of Environmental Protection (NJDEP) initiated a recognition program to highlight Environmental Stewardship as part of its compliance assurance efforts.  For the purposes of NJDEP's new initiative, environmental stewardship is when a regulated entity voluntarily engages in activities that go beyond the minimum requirements, rules and regulations, resulting in a positive benefit to the environment.  This document serves as guidance for the list of questions that comprise the Environmental Stewardship Checklist. This checklist will be used by inspectors to survey facility owner/operators for activities that qualify for recognition as an environmental stewardship activity by the Department during routine inspections. In addition, answers to FAQs and information explaining how a site can achieve recognition as environmental steward are provided.
Bembecinus bytinskii de Beaumont 1954
Creators: name: Gadallah, Neveen S.
name: Abu El-Ghiet, Usama M.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Crabronidae
Bembecinus
Bembecinus bytinskii

description: Bembecinus bytinskii de Beaumont, 1954
Distribution in Jazan and collecting period: Damad (Haffadhiya) on Jasminum sambac (December) (Gadallah et al., 2021).
description: Published as part of Gadallah, Neveen S. & Abu El-Ghiet, Usama M., 2024, Sphecidae sensu lato (Hymenoptera: Apoidea) of the Jazan Province, south-west of Saudi Arabia, with the description of two new species, pp. 71-95 in Zootaxa 5492 (1) on page 79, DOI: 10.11646/zootaxa.5492.1.4, http://zenodo.org/record/13212094
Genomic and eco-epidemiological investigations in Uruguay reveal local Chikungunya virus transmission dynamics during its expansion across the Americas in 2023.
Creators: name: Burgueño, Analía
name: Giovanetti, Marta
name: Fonseca, Vagner
name: Morel, Noelia
name: Lima, Mauricio
name: Castro, Emerson
name: Guimarães, Natália R.
name: Iani, Felipe C. M.
name: Bormida, Victoria
name: Cortinas, Maria Noel
name: Ramas, Viviana
name: Coppola, Leticia
name: Bento, Ana I.
name: Franco, Leticia
name: Rico, Jairo Mendez
name: Lourenço, José
name: Alcantara, Luiz Carlos Junior
name: Chiparelli, Hector
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Uruguay experienced its first Chikungunya virus outbreak in 2023, resulting in a significant burden to its healthcare system. We conducted analysis based on real-time genomic surveillance (30 novel whole genomes) to offer timely insights into recent local transmission dynamics and eco-epidemiological factors behind its emergence and spread in the country.
Associations of time-restricted eating with health-related quality of life and sleep in adults: a secondary analysis of two pre-post pilot studies
Creators: name: Kesztyüs, Dorothea
name: Fuchs, Monika
name: Cermak, Petra
name: Kesztyüs, Tibor
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Time-restricted eating; health-related quality of life
subject: Sleep duration and quality
subject: Employees
subject: Patients
subject: General practitioner
subject: Abdominal obesity
subject: Pilot study
subject: DDC 610 / Medicine & health

description: Abstract Background Therapeutic fasting may improve health-related quality of life (HRQoL) and sleep but is not applicable for everyone. Time-restricted eating (TRE) offers a low threshold alternative but research on associations with HRQoL and sleep is rare. Methods We conducted a secondary analysis of two pilot studies in a pre-post design, which examined TRE in healthy employees at the Ulm University and in abdominal obese patients in a general practitioners office. Participants reported their HRQoL (EQ-5D visual analogue scale) before and after 3 months of restricting their daily eating to 8–9 h. They kept a diary to protocol timing of first and last meal, sleep quality (analogue scale) and duration. Pearson’s correlation coefficient was applied to test bivariate correlations between continuous variables and linear regression analyses were conducted to identify associated factors with the pre-post differences in HRQoL and the differences in sleep quality. Results Ninety-nine participants (aged aged 48.9 ± 1.1, 83.8% female) reached the fasting target of 15–16 h on average on 77.2 ± 18.7% of all recorded days. HRQoL increased by 7.8 ± 12.6 and sleep quality by 9.6 ± 13.9 points, but sleep duration was not extended. Regression analysis revealed mean fasting duration and baseline sleep quality as significant factors associated with changes in HRQoL. Improvements in sleep quality correlated with baseline sleep quality and HRQoL at follow-up but not with fasting. Changes in anthropometry did not correlate with the HRQoL or sleep quality. Conclusions TRE correlates with increased HRQoL and sleep quality independent from weight loss. TRE is easily applicable with or without medical supervision. The potential effects of TRE on health and sleep should be further investigated in larger randomized trials. Trial registration German Register for Clinical Trials (DRKS), DRKS-ID: DRKS00015057. Registered 4 July 2018.
Environmental Stewardship: Moving Beyond Compliance for a Sustainable Future
Creators: name: No Name Supplied
Publisher: name: New Jersey Department of Environmental Protection
Year: 2008

description: As of January 2008, the New Jersey Department of Environmental Protection (NJDEP) initiated a recognition program to highlight Environmental Stewardship as part of its compliance assurance efforts.  For the purposes of NJDEP's new initiative, environmental stewardship is when a regulated entity voluntarily engages in activities that go beyond the minimum requirements, rules and regulations, resulting in a positive benefit to the environment.  This presentation provides information on the background and basis for the development of the Environmental Stewardship program.  It also includes some of the limitations of the program and a timeline.
Quinqueloculina
Creators: name: Mamo, Briony L.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Chromista
Foraminifera
Tubothalamea
Miliolida
Hauerinidae
Quinqueloculina

description: Quinqueloculina sp. 3 (Fig. 11:1, 2)
Description. Test elongate with Quinqueloculina - type coiling, approximately twice as long as wide; oval crosssection. Slightly inflated chambers with distinct, straight, depressed sutures. Rough test wall with patchy, discontinuous, usually weak to moderately defined longitudinal costae extending length of test. Distinct sutures depressed, straight. Aboral end rounded, slightly produced. Aperture terminal, slightly produced, circular with thin peristomal lip; short, bifid, T-shaped tooth.
Remarks. This species has a combination of common morphological features that are often observed as part of the intraspecific variation displayed by other Quinqueloculina species. This species is distinguished from other Quinqueloculina by its elongated test, sporadic longitundal costae, straight sutures and circular aperture with a slight lip and bifid dentition (Fig. 11:1, 2). However, many other species share similarities with Quinqueloculina sp. 3, but there are always fundamental differences. The greatest similarity to Quinqueloculina sp. 3 is shown by Quinqueloculina sp. 2. The general descriptions are extremely similar, but the aboral end of Quinqueloculina sp. 2 is more pronounced, the chambers are more inflated, the test is stouter, the costae are more irregular and the aperture, whilst similar in shape and dentition, is much larger in proportion to the rest of the test. These similarities may indicate conspecificity, but the low abundance of both taxa makes it difficult to be confident and so both taxa have been left in open nomenclature until additional material is available.
Distribution within study area. Quinqueloculina sp. 3 was mainly collected from lagoons of the CG. Abundance was normally low in transect samples and this species was absent from Sykes Reef. Greatest abundance was found at site 42 on Heron Reef flat and sites 25 and 52 in One Tree Lagoon 1 and 2, respectively.
description: Published as part of Mamo, Briony L., 2016, Benthic Foraminifera from the Capricorn Group, Great Barrier Reef, Australia, pp. 1-123 in Zootaxa 4215 (1) on page 49, DOI: 10.11646/zootaxa.4215.1.1, http://zenodo.org/record/272923
Factors associated with diabetic foot ulcers and lower limb amputations in type 1 and type 2 diabetes supported by real‐world data from the German/Austrian DPV registry
Creators: name: Eckert, Alexander J.
name: Zimny, Stefan
name: Altmeier, Marcus
name: Dugic, Ana
name: Gillessen, Anton
name: Bozkurt, Latife
name: Götz, Gabriele
name: Karges, Wolfram
name: Wosch, Frank J.
name: Kress, Stephan
name: Holl, Reinhard W.
Publisher: name: Universität Ulm
Year: 2024
Subjects: subject: Alcohol
subject: Body mass index
subject: Hypertension
subject: Lipids
subject: Sex differences
subject: Smoking
subject: Triglycerides
subject: DDC 610 / Medicine & health

description: Aims Diabetic foot ulcer (DFU) is a leading cause of lower limb amputations in people with diabetes. This study was aimed to retrospectively analyze factors affecting DFU using real-world data from a large, prospective central-European diabetes registry (DPV [Diabetes-Patienten-Verlaufsdokumentation]). Materials and Methods We matched adults with type 1 (T1D) or type 2 diabetes (T2D) and DFU to controls without DFU by diabetes type, age, sex, diabetes duration, and treatment year to compare possible risk factors. Cox regression was used to calculate hazard ratios for amputation among those with DFU. Results In our cohort (N = 63 464), male sex, taller height, and diabetes complications such as neuropathy, peripheral artery disease, nephropathy, and retinopathy were associated with DFU (all p < .001). Glycated hemoglobin (HbA1c) was related to DFU only in T1D (mean with 95% confidence interval [CI]: 7.8 [6.9–9.0] % vs 7.5 [6.8–8.5] %, p < .001). High triglycerides and worse low-density lipoprotein/high-density lipoprotein ratio were also associated with DFU in T1D, whereas smoking (14.7% vs 13.1%) and alcohol abuse (6.4% vs 3.8%, both p < .001) were associated with DFU in T2D. Male sex, higher Wagner grades, and high HbA1c in both diabetes types and insulin use in T2D were associated with increased hazard ratios for amputations. Conclusions Sex, body height, and diabetes complications were associated DFU risk in adults with T1D and T2D. Improvement in glycemic control and lipid levels in T1D and reduction of smoking and drinking in T2D may be appropriate interventions to reduce the risk for DFU or amputations.
Ammatomus yemenensis Schmid-Egger 2019
Creators: name: Gadallah, Neveen S.
name: Abu El-Ghiet, Usama M.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Crabronidae
Ammatomus
Ammatomus yemenensis

description: Ammatomus yemenensis Schmid-Egger, 2019
New material examined: 2♀, Abu Arish, 16–23.iii.2023, Malaise trap on Mangifera indica, Usama Abu El-Ghiet collector; 1♀, Fayfa, vii.2023, Malaise trap on Coffea arabica, Usama Abu El-Ghiet collector.
Distribution in Jazan and collecting period: Abu Arish on Coffea arabica (March), Fayfa on Coffea arabica (July) (present study), Farasan Island (September) (Abu El-Ghiet et al., 2023).
description: Published as part of Gadallah, Neveen S. & Abu El-Ghiet, Usama M., 2024, Sphecidae sensu lato (Hymenoptera: Apoidea) of the Jazan Province, south-west of Saudi Arabia, with the description of two new species, pp. 71-95 in Zootaxa 5492 (1) on page 79, DOI: 10.11646/zootaxa.5492.1.4, http://zenodo.org/record/13212094
Acanthonotozomoides Schellenberg 1931
Creators: name: d'Acoz, Cédric d'Udekem
name: Verheye, Marie L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Acanthonotozomellidae
Acanthonotozomoides

description: Genus Acanthonotozomoides Schellenberg, 1931
Acanthonotozomoides Schellenberg, 1931: 124;
type species: Acanthonotozomoides sublittoralis Schellenberg, 1931.
Acanthonotozomella – K.H. Barnard 1930: 346 (in part).
Acanthonotozomoides – J.L. Barnard 1969: 122. — Bushueva 1978: 452. — De Broyer 1983: 292. — Watling & Thurston 1989: 304, 310. — J.L. Barnard & Karaman 1991: 380, 385. — Coleman & J.L. Barnard 1991a: 257; 1991b: 279. — Coleman 2007: 18.
non Acanthonotozomella Schellenberg, 1926: 332.
Key to the species of Acanthonotozomoides
1. Pereionite 1 with 1 pair of rounded dorsolateral processes ………………………………………… ………………………………………………… Acanthonotozomoides oatesi (K.H. Barnard, 1930)
– Pereionite 1 with 2 pairs of styliform processes …………………………………………………… …………………………………………… Acanthonotozomoides sublitoralis Schellenberg, 1931
description: Published as part of d'Acoz, Cédric d'Udekem & Verheye, Marie L., 2017, Epimeria of the Southern Ocean with notes on their relatives (Crustacea, Amphipoda, Eusiroidea), pp. 1-553 in European Journal of Taxonomy 359 on page 162, DOI: 10.5852/ejt.2017.359, http://zenodo.org/record/3855694
Stewardship Checklist NJEMS Version
Creators: name: No Name Supplied
Publisher: name: New Jersey Department of Environmental Protection
Year: 2008

description: As of January 2008, the New Jersey Department of Environmental Protection (NJDEP) initiated a recognition program to highlight Environmental Stewardship as part of its compliance assurance efforts.  For the purposes of NJDEP's new initiative, environmental stewardship is when a regulated entity voluntarily engages in activities that go beyond the minimum requirements, rules and regulations, resulting in a positive benefit to the environment.  This document lists the questions that are on the Environmental Stewardship Checklist. This checklist will be used by inspectors to survey facility owner/operators for activities that qualify for recognition as an environmental stewardship activity by the Department during routine inspections.