cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplementary document for Deep THz modulation at Fabry-Perot resonances using graphene in periodic microslits - 4929390.pdf
Creators: name: liu, xudong
name: Jia, Mingyang
name: Fan, Shuting
name: Stantchev, Rayko
name: Chen, Xuequan
name: Pickwell-MacPherson, Emma
name: SUN, Yiwen
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Simulation structures of the device without/with metal grating; The THz Time-domain signal with 200 ps optical delay; The peak-to-peak value of the 2nd echo.
Supplementary document for Deep THz modulation at Fabry-Perot resonances using graphene in periodic microslits - 4929390.pdf
Creators: name: liu, xudong
name: Jia, Mingyang
name: Fan, Shuting
name: Stantchev, Rayko
name: Chen, Xuequan
name: Pickwell-MacPherson, Emma
name: SUN, Yiwen
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Simulation structures of the device without/with metal grating; The THz Time-domain signal with 200 ps optical delay; The peak-to-peak value of the 2nd echo.
Workflow and process synchronization with interaction expressions and graphs
Creators: name: Heinlein, Christian
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 004 / Data processing & computer science
subject: Workflow; Management

description: Interaction expressions and graphs are proposed as a simple yet powerful formalism for the specification and implementation of synchronization conditions in general and inter-workflow dependencies in particular.
Data on the environment 2017
Creators: name: Arle, Jens
name: Balzer, Frederike
name: Baumgarten, Corinna
name: Bilharz, Michael
name: Bünger, Björn
name: Dauert, Ute
name: Dewitz, Anja
name: Drosihn, Detlef
name: Eckermann, Frauke
name: Ehlers, Knut
name: Frerk, Michel
name: Gellrich, Angelika
name: Geupel, Markus
name: Gniffke, Patrick
name: Golde, Michael
name: Grimski, Detlef
name: Günther, Jens
name: Hermann, Sebastian
name: Hilliges, Falk
name: Hintzsche, Matthias
name: Hofmeier, Maximilian
name: Kallweit, Dagmar
name: Kartschall, Karin
name: Kessinger, Susan
name: Köder, Lea
name: Kohlmeyer, Regina
name: Langner, Marcel
name: Leujak, Wera
name: Leuthold, Sandra
name: Ludwig, Anett
name: Mohaupt, Volker
name: Mohr, Lennart
name: Papenroth, Lysann
name: Penn-Bressel, Gertrude
name: Pohl, Marian
name: Richter, Nadja
name: Schnepel, Jürgen
name: Schütze, Gudrun
name: Schwermer, Sylvia
name: Szewzyk, Regine
name: Timme, Stephan
name: Töpfer, Christoph
name: Werner, Stefanie
name: Wintermeyer, Dirk
name: Wolter, Rüdiger
Publisher: name: My University
Year: 2017
Subjects: subject: Data on the Environment
subject: environmental data
subject: Sustainability | Strategies | International matters

description: In its indicator report Data on the Environment 2017, the German Environment Agency gives a comprehensive overview of the state of the environment, the causes of environmental pollution and leverage points for improvement. A total of 50 indicators have been selected from all environmental domains and, wherever possible, underpinned by policy targets, as defined in documents such as the German Sustainable Development Strategy or EU directives. Thus, the environmental indicator system is also a record of environmental policy. Quelle: https://www.umweltbundesamt.de/
description: In its indicator report Data on the Environment 2017, the German Environment Agency gives a comprehensive overview of the state of the environment, the causes of environmental pollution and leverage points for improvement. A total of 50 indicators have been selected from all environmental domains and, wherever possible, underpinned by policy targets, as defined in documents such as the German Sustainable Development Strategy or EU directives. Thus, the environmental indicator system is also a record of environmental policy.
Transition planning with adolescents who stutter (Rodgers et al., 2025)
Creators: name: Rodgers, Naomi H.
name: Marsh, Darby
name: Jacobs, Kelly
name: Collins, Ginger G.
Publisher: name: ASHA journals
Year: 2025
Subjects: classificationCode: 390306
subject: Secondary education
classificationCode: 520101
subject: Child and adolescent development
classificationCode: 420110
subject: Speech pathology

description: Purpose: The purpose of this project was to understand the needs of adolescents who stutter as they transition to life after high school, and to develop an evidence-based discussion guide for speech-language pathologists (SLPs) to use in their postsecondary transition planning with adolescents who stutter.Method: We conducted four focus groups: two with current high schoolers who stutter and recent high school graduates who stutter (n = 11) and two with parents of high schoolers who stutter and high school–based SLPs (n = 14). The focus groups were recorded, transcribed, and analyzed using reflexive thematic analysis.Results: Three to five themes were created for each of the three main domains of transition plans: postsecondary education/training, employment, and independent living. While the themes were unique to each postsecondary domain, there was a common thread of helping adolescents develop an open, proactive stance toward stuttering and discussing stuttering with others.Conclusions: SLPs are uniquely positioned to guide adolescents who stutter through the postsecondary transition process, as they are often the only specialized support personnel working with students who stutter in the schools. There are discussion topics that are important to facilitate with adolescents who stutter as they prepare to transition to life after high school, which we present in a printable discussion guide located as supplemental material to this article.Supplemental Material S1. Postsecondary transition planning with students who stutter discussion guide.Rodgers, N. H., Marsh, D., Jacobs, K., & Collins, G. G. (2025). Preparing adolescents who stutter for the transition to life after high school. Language, Speech, and Hearing Services in Schools. Advance online publication. https://doi.org/10.1044/2025_LSHSS-24-00082
Cosmic-ray extremely distributed observatory: Status and perspectives
Creators: name: Góra, Dariusz
name: Cheminant, Kevin Almeida
name: Alvarez-Castillo, David
name: Bratek, Łukasz
name: Dhital, Niraj
name: Duffy, Alan
name: Homola, Piotr
name: Jagoda, Pawel
name: Jałocha, Joanna
name: Kasztelan, Marcin
name: Kopanski, Konrad
name: Kovacs, Peter
name: Nazari, Vahab
name: Niedzwiecki, Michal
name: Ostrogórski, Dominik
name: Smołek, Karel
name: Stasielak, Jaroslaw
name: Sushchov, Oleksander
name: Wozniak, Krzysztof W.
name: Zamora-Saa, Jilberto
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: The Cosmic-Ray Extremely Distributed Observatory (CREDO) is a project dedicated to global studies of extremely extended cosmic-ray phenomena, the cosmic-ray ensembles (CRE), beyond the capabilities of existing detectors and observatories. Up to date, cosmic-ray research has been focused on detecting single air showers, while the search for ensembles of cosmic-rays, which may overspread a significant fraction of the Earth, is a scientific terra incognita. Instead of developing and commissioning a completely new global detector infrastructure, CREDO proposes approaching the global cosmic-ray analysis objectives with all types of available detectors, from professional to pocket size, merged into a worldwide network. With such a network it is possible to search for evidences of correlated cosmic-ray ensembles. One of the observables that can be investigated in CREDO is a number of spatially isolated events collected in a small time window which could shed light on fundamental physics issues. The CREDO mission and strategy requires active engagement of a large number of participants, also non-experts, who will contribute to the project by using common electronic devices (e.g., smartphones). In this note, the status and perspectives of the project are presented.
Interventions on children’s and adolescents’ physical activity and sedentary behaviour: protocol for a systematic review from a sex/gender perspective
Creators: name: Demetriou, Yolanda
name: Vondung, Catherina
name: Bucksch, Jens
name: Schlund, Annegret
name: Schulze, Carolin
name: Knapp, Guido
name: Coen, Stephanie E
name: Puil, Lorri
name: Phillips, Susan P
name: Reimers, Anne K
Publisher: name: BioMed Central
Year: 2019

description: Background: Low levels of physical activity (PA) and high levels of sedentary behaviour (SB) have been observed in young people. Both behaviours are detrimental for health with patterns tending to continue into adulthood. There is sustained value in establishing health habits in early years. Even though levels of SB and participation in PA differ among boys and girls, and the effectiveness of interventions to promote PA and/or prevent sedentary behaviours varies by sex/gender to date, sex/gender in systematic reviews is not yet widely considered. Additionally, while tools have been proposed, there is no consensus on the criteria to assess sex/gender in systematic reviews in the context of health promotion. The main objectives of this systematic review are to evaluate the effects of interventions on girls’ and boys’ PA and SB and to appraise the extent to which the studies have taken sex/gender into account. Methods: Eleven electronic databases will be searched to identify all relevant (randomized) controlled trials. Two independent reviewers will screen studies, extract data and appraise the quality of studies. The main outcome of the studies will be a quantified measure of PA and/or SB. Risk of bias of individual studies will be assessed using the Cochrane Risk of Bias Tool for RCTs. Meta-analyses will be conducted when possible among studies with sufficient homogeneity. To evaluate sex/gender considerations in primary studies, we will use a sex/gender checklist that builds on existing tools and was developed during a 2-day, iterative process among a multidisciplinary panel of 16 experts. The GRADE framework will be used to evaluate evidence across studies for each main efficacy outcome. Discussion: To our knowledge, our systematic review will be the first to analyse how sex/gender is considered in interventions promoting PA and/or reducing SB in children and adolescents in detail. The review will provide information on how sex/gender aspects have been considered in recent research and the extent to which sex/gender might impact study outcomes. Our findings will be of interest to stakeholders, health promoters, researchers and policy makers who wish to support more equal outcomes from interventions promoting PA and/or reducing SB. Trial registration PROSPERO CRD42018109528 .
A performance comparison of TRACA: an incremental on-line learning algorithm
Creators: name: Mitchell, Matthew W.
Publisher: name: Swinburne
Year: 2024

description: TRACA (Temporal Reinforcement-learning and Classification Architecture) is a learning system intended for robot-navigation tasks. One problem in this area is input-generalisation. Input generalisation requires learning a small set of internal states which represent useful abstractions of the much larger set of actual states. As such, the input-generalisation problem is fundamentally similar to the classical problems of classification, concept learning and discrimination. The priorities when evaluating a system for on-line robot learning include a small number of trials, predictive accuracy and minimal parameter tuning. Other requirements are the ability to learn without predefined classes (i.e. classes must be learned during training) and an efficient and adaptable representation. This paper evaluates the performance of TRACA, a new learning algorithm, on a number of common classification tasks. The same set of parameters is used to obtain all TRACA's results, which are then compared to the results obtained by other well-known algorithms. On most tasks, TRACA's predictive accuracy is within a few percent of the best performing systems compared. Furthermore, TRACA's result is often achieved with less training experience. In a final experiment TRACA is trialled on a robot navigation task that requires discrimination of a number of discrete locations.
Contested Knowledges in Hydroelectric Project Assessment: The Case of Canada’s Site C Project
Creators: name: Bakker, Karen
name: Hendriks, Richard
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: This paper analyzes contestation over aspects of the Site C Project on the Peace River in northeastern British Columbia, Canada. The $10.7 billion project, which is now under construction, has been vigorously debated for over 30 years. Initially proposed in the 1980s, project approval was not granted following review by the BC Utilities Commission, as the need for the project was not established. In 2010, the provincial government enacted legislation to exempt the project from future review by the BC Utilities Commission; an environmental assessment was initiated in 2012 and a constrained review by the Commission was undertaken in 2017, after construction had commenced. The paper explores key examples of contested knowledge regimes within the review process, focusing on debates over cumulative effects and greenhouse gas emissions. The analysis provides technical examples of the ways in which differing societal values are deployed and co-produced within regulatory processes.
Supplementary document for Photonic chip-based resonant supercontinuum - 4930365.pdf
Creators: name: Anderson, Miles
name: Bouchand, Romain
name: Liu, Junqiu
name: Weng, Wenle
name: Obrzud, Ewelina
name: Herr, Tobias
name: Kippenberg, Tobias
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Latex files for the supp. info document
ACEITAÇÃO DOS RESPONSÁVEIS FRENTE ÀS TÉCNICAS DE MANEJO COMPORTAMENTAL EM ODONTOPEDIATRIA
Creators: name: Gabrielly Lemos GOMES
name: Janine Mayra da SILVA
Publisher: name: Zenodo
Year: 2024
Subjects: Odontopediatria
Condicionamento comportamental
Ansiedade

description: RESUMO

O papel do odontopediatra vai além do tratamento odontológico infantil; envolve estabelecer uma relação sólida com pais e crianças, fundamental para o sucesso terapêutico. É crucial fornecer informações claras e ilustrativas sobre o controle comportamental, pois o nível de ansiedade dos responsáveis influencia diretamente o comportamento dos pequenos no consultório. A pesquisa, realizada através de artigos selecionados nas plataformas acadêmicas, identificou as técnicas de manejo comportamental infantil mais eficazes em odontopediatria. Com base nisso, elaborou- se uma cartilha informativa e um e-book, distribuídos em uma clínica odontológica privada em Belo Horizonte e adaptados para a Clínica Escola de Odontologia da Faculdade de Minas. Discute-se a importância da comunicação prévia e objetiva com os responsáveis para diminuir a ansiedade, destacando estudos, como o de Tomita et al., que evidenciam a eficácia dessa abordagem na redução da ansiedade dos pais e na colaboração das crianças durante o tratamento. Conclui-se que o entendimento dos responsáveis sobre as técnicas de condicionamento comportamental é vital para o sucesso da intervenção odontológica. Portanto, é essencial que o odontopediatra forneça informações preventivas antes da consulta clínica, promovendo a participação dos pais ao longo do procedimento e construindo uma relação de confiança entre todas as partes envolvidas.
Strength-deformation behaviour of a weathered clay crust.
Creators: name: Khan, Md. Mahbubul A.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Engineering, Civil.

description: The purpose of this research was to study the strength-deformation behaviour of a weathered clay crust in the Ottawa region. This study includes an extensive experimental programme, covering both field and laboratory tests. The field testing methods used were the field vane, the dilatometer, the piezocone, and the self-boring pressuremeter. Triaxial shear and consolidation tests were conducted in the laboratory testing programme. Conventional triaxial tests, in both compression and extension, and non-conventional stress-path tests covering various stress-paths in the triaxial space, were performed in this study. Constant rate of strain, constant rate of load, controlled gradient, as well as the conventional oedometer tests were conducted in the consolidation testing programme. In order to perform the laboratory experiments, a computer-operated triaxial stress-path control system and an automated consolidation apparatus were developed. The software for the automation of the above apparatus was also developed in this research. A laboratory method for the evaluation of in situ K$\sb0$ for highly overconsolidated soil has been proposed. Such a method is necessary for the stress-path triaxial tests, where reconsolidation of the triaxial sample to in situ state of stress is required. A new method of interpretation of field vane (FV) test, for anisotropic soil, has also been developed. In this method, the original equation for the interpretation of FV has been reformulated which includes the strength anisotropy of the soil, non-uniform stress distribution around the FV, effect of rate of shearing and the disturbance due to vane insertion. From the analysis of the laboratory triaxial and consolidation tests, for various depths within the crust, a well defined yield envelope was obtained. This yield envelope can be used to estimate the elastic and plastic strains for any stress-path in the field. The test results obtained from various laboratory and field tests have been compared with two case studies from the same site, and demonstrate the importance of the consideration of the in situ stress state.
Supplementary document for Photonic chip-based resonant supercontinuum - 4930365.pdf
Creators: name: Anderson, Miles
name: Bouchand, Romain
name: Liu, Junqiu
name: Weng, Wenle
name: Obrzud, Ewelina
name: Herr, Tobias
name: Kippenberg, Tobias
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Latex files for the supp. info document
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 233 (29. Jg.), November 1999
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Uni Ulm intern
subject: Universities; Germany; Ulm
subject: Ulm / Universität

description: N/A
Resolution improvement in two-photon fluorescence microscopy with a single-mode fiber
Creators: name: Bird, Damian
name: Gu, Min
Publisher: name: Swinburne
Year: 2024

description: The dependence of spectral broadening of an ultrashort-pulsed laser beam on the fiber length and the illumination power is experimentally characterized in order to deliver the laser for two-photon fluorescence microscopy. It is found that not only the spectral width but also the spectral blue shift increases with the fiber length and illumination power, owing to the nonlinear response in the fiber. For an illumination power of 400mWin a 3-m-long single-mode fiber, the spectral blue shift is as large as 15 nm. Such a spectral blue shift enhances the contribution from the short-wavelength components within the pulsed beam and leads to an improvement in resolution under two-photon excitation, whereas the efficiency of two-photon excitation is slightly reduced because of the temporal broadening of the pulsed beam. The experimental measurement of the axial response to a two-photon fluorescence polymer block confirms this feature. © 2002 Optical Society of America.
Les réécritures de Jocaste ou la paradoxale réhabilitation d'une "mère coupable"
Creators: name: Gauthier, Alexandre
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Literature, Modern.
subject: Literature, Canadian (French).

description: Analyse dramaturgique comparée des réécritures françaises du mythe d'OEdipe, cette thèse se concentre plus particulièrement sur le personnage de Jocaste, qui semble avoir été réhabilitée, au fil des époques, par le théâtre. Personnage très secondaire dans l'OEdipe Roi de Sophocle, les auteurs français vont peu à peu lui accorder le statut de sujet. Nous abordons cette évolution d'abord selon des critères dramaturgiques -- la présence scénique, les fonctions dramaturgiques -- qui permettent de mettre au jour le développement scénique de Jocaste et l'importance que les auteurs lui accordent dans l'économie de la fable. Puis, l'évolution sera abordée selon des critères thématiques -- l'ambiguïte amoureuse, la culpabilité -- qui révèlera les nombreuses variations que subit Jocaste d'une pièce à l'autre. Ces variations témoignent, de manière plus générale, des ambitions et des tentations dramaturgiques des différents auteurs, mais aussi des enjeux sociaux, politiques ou religieux des divers contextes de production.
Chronic exposures to the herbicide atrazine and the pharmaceutical finasteride disrupt sex steroid and thyroid hormone signalling and gonadal development in frogs
Creators: name: Langlois, Valerie S
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Biology, Endocrinology.

description: Endocrine disrupting chemicals (EDCs) such as pesticides and pharmaceuticals can upset amphibian development and contribute to worldwide amphibian population declines. The first objective of this doctoral research was to investigate if the widely used herbicide atrazine (ATZ; used on corn and soy crops) alters Lithobates (Rana) pipiens (Northern leopard frog) development using concentrations of ATZ reported in Canadian ecosystems. Chronic exposures to 0.1 and 1.8 mug/L ATZ on L. pipiens tadpoles were performed in semi-controlled mesocosms. Atrazine reduced metamorphosic success, induced female-biased sex ratio, altered the hepatic activity of steroid 5beta-reductase (srd5beta; an enzyme involves in the conversion of testosterone into 5beta-dihydrotestosterone) and affected the expression of estrogen receptor alpha in brain and deiodinase type 3 in tail. The second objective was to characterize the functions of the steroid 5alpha-reductase (srd5alpha; type 1, 2 and 3) and srd5beta in frogs. These enzymes represent a convergence in evolution: they share similar biological functions (e.g., testosterone reduction, bile acid biosynthesis and erythropoesis), but srd5alpha and srd5beta do not have a common ancestor. Using real-time RT-PCR analysis, these enzymes were detected throughout Silurana (Xenopus) tropicalis (Western clawed frog) early development. The prostate drug finasteride (a 5alpha-reductase type 2 and srd5beta inhibitor in humans) was used in short-term (25, 50 and 100 muM) and chronic (25 muM) exposures of S. tropicalis under laboratory conditions. Finasteride inhibited srd5beta and aromatase (cyp19) activities in whole embryos after short-term exposures. However, chronically exposed S. tropicalis until metamorphosis, revealed no effects of finasteride on cyp19 activity and an increase in male hepatic srd5beta activity. Furthermore, chronic treatment with finasteride induced testicular oocytes in developing males (also referred to as the intersex condition). In addition, real-time RT-PCR analysis showed that finasteride treatments altered sex steroid- and thyroid hormone-related gene expression. Alterations of thyroid hormone gene expression following the inhibition of srd5alpha and srd5beta suggest a complex relationship between the thyroid hormone-responsive genes and the androgen status in early frog development and at metamorphosis. In conclusion, real-time RT-PCR, enzymatic activity and histology analyses demonstrated that srd5alpha and srd5beta are important enzymes during frog development and are 'new' targets to EDCs.
Tissue Factor and COVID-19 Associated Thrombosis
Creators: name: Mackman N.
Publisher: name: Lippincott Williams and Wilkins
Year: 2024

description: Microbial infections activate the innate and adaptive immune systems.1Pathogen-associated molecular patterns produced by microbes, such as double-stranded RNA, are detected by PRRs (pattern-recognition receptors), such as toll-like receptor 3, and this leads to the expression of interferons and cytokines.
Mixed dynamical decoupling
Creators: name: Genov, Genko T
name: Aharon, Nati
name: Jelezko, Fedor
name: Retzker, Alex
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: quantum memory
subject: quantum sensing
subject: dynamical decoupling
subject: coherent control
subject: DDC 530 / Physics
subject: Dynamics
subject: Dynamik

description: Abstract We propose a scheme for mixed dynamical decoupling (MDD), where we combine continuous dynamical decoupling with robust sequences of phased pulses. Specifically, we use two fields for decoupling, where the first continuous driving field creates dressed states that are robust to environmental noise. Then, a second field implements a robust sequence of phased pulses to perform inversions of the dressed qubits, thus achieving robustness to amplitude fluctuations of both fields. We show that MDD outperforms standard concatenated continuous dynamical decoupling in realistic numerical simulations for dynamical decoupling in NV centers in diamond. Finally, we also demonstrate how our technique can be utilized for improved sensing.
Prognostic impact of PD-L1 expression in malignant salivary gland tumors as assessed by established scoring criteria: tumor proportion score (TPS), combined positivity score (CPS), and immune cell (IC) infiltrate
Creators: name: Witte, Hanno M.
name: Gebauer, Niklas
name: Lappöhn, Daniela
name: Umathum, Vincent G.
name: Riecke, Armin
name: Arndt, Annette
name: Steinestel, Konrad
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: salivary gland carcinoma
subject: immuno-oncology
subject: PD-L1
subject: checkpoint inhibition
subject: DDC 610 / Medicine & health
subject: Salivary gland neoplasms
subject: Neoplasms; Immunology
subject: Speicheldrüsenkrebs
subject: Tumorimmunologie

description: Background: Malignant neoplasms of the salivary glands are rare, and therapeutic options are limited. Results from recently published studies indicate a possible use for checkpoint inhibition in a subset of patients, but there are no established criteria for programme cell death ligand 1 (PD-L1) scoring in salivary gland carcinomas (SGCs). Methods: In this retrospective study, we present a cohort of 94 SGC patients with full clinical follow-up. We included 41 adenoid cystic carcinomas (AdCC), 21 mucoepidermoid carcinomas (MEC), 16 acinic cell carcinomas (ACC), 12 adenocarcinomas, not otherwise specified (AC, NOS), 2 epithelial-myoepithelial carcinomas (EMC), one salivary duct carcinoma (SDC), and one carcinoma ex pleomorphic adenoma (CA ex PA). Subsequent histopathological analysis was performed with special emphasis on the composition of the immune cell infiltrate (B-/T-lymphocytes). We assessed PD-L1 (SP263) on full slides by established scoring criteria: tumor proportion score (TPS), combined positivity score (CPS) and immune cell (IC) score. Results: We identified significantly elevated CD3+, TP, CP, and IC scores in AC, NOS compared to AdCC, MEC, and ACC. CPS correlated with node-positive disease. Moreover, AC, NOS displayed IC scores of 2 or 3 in the majority (67%) of cases (p = 0.0031), and was associated with poor prognosis regarding progression-free (PFS) (p < 0.0001) and overall survival (OS) (p < 0.0001). CPS correlated with strong nuclear or null p53 staining in AC, NOS but not in other SGCs. Long-lasting partial remission could be achieved in one AC, NOS patient who received Pembrolizumab as third-line therapy. Conclusions: The current study is the first to investigate the use of established scoring criteria for PD-L1 expression in malignant salivary gland tumors. Our findings identify unique characteristics for AC, NOS among the family of SGCs, as it is associated with poor prognosis and might represent a valuable target for immune checkpoint inhibition.
Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperglycemia-Induced Damage, An Exploratory Analysis
Creators: name: Durrer, Cody
name: Lewis, Nia
name: Wan, Zhongxiao
name: Ainslie, Philip N., 1974-
name: Jenkins, Nathan T.
name: Little, Jonathan P.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Postprandial hyperglycemia has been linked to elevated risk of cardiovascular disease. Endothelial dysfunction and/or damage may be one of the mechanisms through which this occurs. In this exploratory study, we determined whether acute glucose ingestion would increase markers of endothelial damage/activation and impair endothelial function before and after a short-term low-carbohydrate high-fat diet (HFD) designed to induce relative glucose intolerance. Nine healthy young males (body mass index 23.2 ± 2 kg/m2) consumed a 75 g glucose drink before and <24 hours after consuming seven days of an iso-energetic HFD consisting of ~70% energy from fat, ~10% energy from carbohydrates, and ~20% energy from protein. CD31+/CD42b- and CD62E+ endothelial microparticles (EMPs) were enumerated at fasting, 1 hour (1 h), and 2 hours (2 h) post-consumption of the glucose drink. Flow-mediated dilation (FMD), arterial stiffness, and diameter, velocity, and flow of the common and internal carotid, and vertebral arteries were assessed in the fasting state and 1 h post glucose consumption. After the HFD, CD31+/CD42b- EMPs were elevated at 1 h compared to 2 h (p = 0.037), with a tendency for an increase above fasting (p = 0.06) only post-HFD. CD62E EMPs followed the same pattern with increased concentration at 1 h compared to 2 h (p = 0.005) post-HFD, with a tendency to be increased above fasting levels (p = 0.078). FMD was reduced at 1 h post glucose consumption both pre- (p = 0.01) and post-HFD (p = 0.005). There was also a reduction in FMD in the fasting state following the HFD (p = 0.02). In conclusion, one week of low-carbohydrate high-fat feeding that leads to a relative impairment in glucose homeostasis in healthy young adults may predispose the endothelium to hyperglycemia-induced damage.
Supplementary document for Fabry-Perot effect and performance enhancement in magneto-optical InSb-based Terahertz Faraday isolator - 4931801.pdf
Creators: name: Keshock, Elise
name: Peng, Peisong
name: Zhou, Jiangfeng
name: Talbayev, Diyar
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
title: Error models for the kinetic evaluation of chemical degradation data
title: Error models for the kinetic evaluation of chemical degradation data
titleType: AlternativeTitle
Creators: name: Meinecke, Stefan
name: Ranke, Johannes
Publisher: name: My University
Year: 2019
Subjects: Chemische Zersetzung

description: In the kinetic evaluation of chemical degradation data, degradation models are fitted to the data by varying degradation model parameters to obtain the best possible fit. Today, constant variance of the deviations of the observed data from the model is frequently assumed (error model "constant variance"). Allowing for a different variance for each observed variable ("variance by variable") has been shown to be a useful refinement. On the other hand, experience gained in analytical chemistry shows that the absolute magnitude of the analytical error often increases with the magnitude of the observed value, which can be explained by an error component which is proportional to the true value. Therefore, kinetic evaluations of chemical degradation data using a two-component error model with a constant component (absolute error) and a component increasing with the observed values (relative error) are newly proposed here as a third possibility. In order to check which of the three error models is most adequate, they have been used in the evaluation of datasets obtained from pesticide evaluation dossiers published by the European Food Safety Authority (EFSA). For quantitative comparisons of the fits, the Akaike information criterion (AIC) was used, as the commonly used error level defined by the FOrum for the Coordination of pesticide fate models and their USe(FOCUS) is based on the assumption of constant variance. A set of fitting routines was developed within the mkin software package that allow for robust fitting of all three error models. Comparisons using parent only degradation datasets, as well as datasets with the formation and decline of transformation products showed that in many cases, the two-component error model proposed here provides the most adequate description of the error structure. While it was confirmed that the variance by variable error model often provides an improved representation of the error structure in kinetic fits with metabolites, it could be shown that in many cases, the two-component error model leads to a further improvement. In addition, it can be applied to parent only fits, potentially improving the accuracy of the fit towards the end of the decline curve, where concentration levels are lower. Quelle: http://www.mdpi.com
On the complexity of consistency problems for neurons with binary weights
Creators: name: Schmitt, Michael
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 004 / Data processing & computer science
subject: Neural networks (Computer science)
subject: NP-complete problems
subject: Neuronales Netz

description: We inquire into the complexity of training a neuron with binary weights when the training examples are Boolean and required to have bounded coincidence and heaviness. Coincidence of an example set is defined as the maximum inner product of two elements, heaviness of an example set is the maximum Hamming-weight of an element. We use both as parameters to define classes of restricted consistency problems and ask for which values they are NP-complete or solvable in polynomial time.
Decellularized bone matrix grafts for calvaria regeneration
Creators: name: Lee, Yan Ting
name: Tang, Na
name: Lee, Dong Joon
name: Zou, Rui
name: Ko, Ching-Chang
name: Han, Han
name: Chen, Xin
name: Zhao, Lixing
name: Diachina, Shannon
Publisher: name: SAGE Publications
Year: 2016

description: Decellularization is a promising new method to prepare natural matrices for tissue regeneration. Successful decellularization has been reported using various tissues including skin, tendon, and cartilage, though studies using hard tissue such as bone are lacking. In this study, we aimed to define the optimal experimental parameters to decellularize natural bone matrix using 0.5% sodium dodecyl sulfate and 0.1% NH4OH. Then, the effects of decellularized bone matrix on rat mesenchymal stem cell proliferation, osteogenic gene expression, and osteogenic differentiations in a two-dimensional culture system were investigated. Decellularized bone was also evaluated with regard to cytotoxicity, biochemical, and mechanical characteristics in vitro. Evidence of complete decellularization was shown through hematoxylin and eosin staining and DNA measurements. Decellularized bone matrix displayed a cytocompatible property, conserved structure, mechanical strength, and mineral content comparable to natural bone. To study new bone formation, implantation of decellularized bone matrix particles seeded with rat mesenchymal stem cells was conducted using an orthotopic in vivo model. After 3 months post-implantation into a critical-sized defect in rat calvaria, new bone was formed around decellularized bone matrix particles and also merged with new bone between decellularized bone matrix particles. New bone formation was analyzed with micro computed tomography, mineral apposition rate, and histomorphometry. Decellularized bone matrix stimulated mesenchymal stem cell proliferation and osteogenic differentiation in vitro and in vivo, achieving effective bone regeneration and thereby serving as a promising biological bone graft.
A Jewish conductor, a devoted Mahlerite, and a delicate string: The musical life of Heinz Unger, 1895--1965
Creators: name: Tesler-Mabe, Hernan
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Biography.
subject: Music.
subject: History, Modern.
subject: Jewish Studies.

description: The orchestral conductor Heinz Unger (1895-1965) was born in Berlin, Germany and was reared from a young age to follow in his father's footsteps and become a lawyer. In 1915, he heard a Munich performance of Gustav Mahler's Das Lied von der Erde conducted by Bruno Walter and thereafter devoted the rest of his life to music and particularly to the dissemination of Gustav Mahler's music. This doctoral dissertation is conceived as a contextual biography that explores the manner in which the strands of German Jewish identity converge and are negotiated by a musician who, as a consequence of persecution, lived a sizeable portion of his life in a Double Diaspora (in the Jewish Diaspora as well as exiled from his European home) yet never cut the ties to a German Jewish tradition informed by the strains of a European cultural heritage. It is a work that discusses the process of Jewish emancipation in Central Europe and in so doing sheds light on the complex issues of ethnicity, "race," nationalism, secularization, and culture and thought as they developed in the modern period and impacted upon Europe and beyond in the first half of the twentieth century. In tracking Heinz Unger's many movements and activities around the world and covering his eventual emigration to Canada, the work simultaneously probes the manner in which European cultural values manifested themselves in disparate parts of the world. It is also a detailed examination of the values that Mahler's oeuvre represents and of one musician's negotiation of these sites of meaning by way of his commitment to Gustav Mahler's music. The first three chapters serve as an extended introduction that in turn surveys Jewish identity in the Diaspora, constructions of Jewish music and their meaning, and the specific cultural significance of Mahler's music in a German Jewish context. The following five chapters are cast as a biography of Heinz Unger (based on the Heinz Unger Fonds at Archives Canada, Ottawa, Ontario) that explores the manner in which the German Jewish musician understood and expressed his dual identity by way of his allegiance to music.
Trusting the People and the System. The Interrelation Between Interpersonal and Institutional Trust in Collective Action for Agri-Environmental Management
Creators: name: De Vries, Jasper R.
name: Van Der Zee, Eva
name: Beunen, Raoul
name: Kat, Rianne
name: Feindt, Peter
Publisher: name: Humboldt-Universität zu Berlin
Year: 2019
Subjects: subject: trust
subject: collective action
subject: agri-environmental management
subject: the Netherlands
subject: collectives
subject: 333.7 Natürliche Resourcen, Energie und Umwelt
subject: 690 Hausbau, Bauhandwerk

description: Agri-environmental schemes have been introduced in numerous countries to combat biodiversity loss in agrarian landscapes that are important for both food production and biodiversity. The successful operation of such schemes depends strongly upon trust between actors involved, as well as trust in institutions that govern these schemes. However, the interplay between interpersonal and institutional trust in the context of collective action for agri-environmental management is not well understood. To address this question, we explore the case of agri-environmental management in the province of Drenthe (in The Netherlands), where a new policy model was implemented. This case shows how both institutional design and institutional performance critically influence trust dynamics. Under the old policy model, farmers struggled with auditing and control, which fostered mistrust and hampered collective action. Under the new model, a landscape approach, more responsibilities were delegated to farmers, and more room was created for interaction, which fostered trust both between actors and in institutions. Based on our findings, we conclude that institutional designs that reflect trust in the actors can foster interpersonal and institutional trust that, in turn, facilitates collective action. However, old arrangements can also create path dependencies that limit trust development and impede collective action for agri-environmental management.
title: SEGUIMIENTO DEL CANCER DE PULMÓN:  Valoración radiológica en los criterios de respuesta al tratamiento oncológico.
Creators: name: Casals Vila, Sonia
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neoplasia
subject: Outcomes analysis
subject: CT
subject: PET-CT
subject: Lung
subject: Oncology

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisar los criterios de respuesta utilizados en el seguimiento del carcinoma de pulmón no microcítico (CPNM).
Definir cuáles son los principales cambios descritos en la oncoguía RECIST 1.1 con respecto al RECIST 1.0,
relacionados con los...
Optimal acceleration voltage for near-atomic resolution imaging of layer-stacked 2D polymer thin films
Creators: name: Liang, Baokun
name: Zhang, Yingying
name: Leist, Christopher
name: Ou, Zhaowei
name: Položij, Miroslav
name: Wang, Zhiyong
name: Mücke, David Christian
name: Dong, Renhao
name: Zheng, Zhikun
name: Heine, Thomas
name: Feng, Xinliang
name: Kaiser, Ute
name: Qi, Haoyuan
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: DDC 570 / Life sciences
subject: Transmission electron microscopy
subject: Two-dimensional materials
subject: Raster-Transmissions-Elektronenmikroskopie

description: Despite superb instrumental resolution in modern transmission electron microscopes (TEM), high-resolution imaging of organic two-dimensional (2D) materials is a formidable task. Here, we present that the appropriate selection of the incident electron energy plays a crucial role in reducing the gap between achievable resolution in the image and the instrumental limit. Among a broad range of electron acceleration voltages (300 kV, 200 kV, 120 kV, and 80 kV) tested, we found that the highest resolution in the HRTEM image is achieved at 120 kV, which is 1.9 Å. In two imine-based 2D polymer thin films, unexpected molecular interstitial defects were unraveled. Their structural nature is identified with the aid of quantum mechanical calculations. Furthermore, the increased image resolution and enhanced image contrast at 120 kV enabled the detection of functional groups at the pore interfaces. The experimental setup has also been employed for an amorphous organic 2D material.
Understanding government Web communication strategy as applied within the Public Health Agency of Canada
Creators: name: Knazko, Jana
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Health Sciences, Public Health.
subject: Political Science, Public Administration.
subject: Information Science.

description: The research examines the components that make up the Web communication strategy of the Public Health Agency of Canada (PHAC). The thesis focuses on the extent to which PHAC's Web site reflects its mandate and implements the Government of Canada's public policies that regulate its Web presence. The Web communication strategy is analyzed from the perspective of Johnson's conceptualization model which separates a discourse into the stages of production, text, and context. The methodology employs content analysis and interviews to illustrate to which extent the democratic rights of the public were taken into account when the Web strategy was elaborated and how the public and PHAC stakeholders benefit from the implementation of this strategy. The research finds that although the general public is considered to be an important audience segment of the PHAC Web site, the emphasis of Web policy is to reinforce health care, education, and government sector stakeholder relationships. Keywords. public health agency, health Web site, Web analytics, communications policy, e-communications, accessibility, stakeholders, government Web.
Distal Extrusion and Impending Cylinder Erosion of the Penile Prosthesis: a Clinical Challenge for the Urologist
Creators: name: Coward, Robert M.
name: Carson, Culley C.
name: Sukhu, Troy
Publisher: name: Springer Nature
Year: 2016

description: Distal extrusion with impending cylinder erosion through the distal corpus cavernosum is a significant complication of penile prosthesis surgery. Surgical repair is indicated to prevent cylinder perforation or erosion through the skin, which leads to infection and requires removal of all prosthesis components. The underlying cause is typically unrecognized tunical perforation during surgery, aggressive distal dilation, oversized cylinders, or repeated trauma. Extrusion is more common in patients with microangiopathy, prior radiation, corporal fibrosis, or decreased distal sensation. The two most prevalent methods for repair are distal corporoplasty or windsock graft reconstruction. Distal corporoplasty has been demonstrated to have superior outcomes to windsock grafts and is the method of repair that these authors favor. The goal of this review is to provide a background on distal penile prosthesis extrusion, along with potential treatment approaches, so that the surgeon may be familiar with this seemingly difficult, albeit rare, complication of penile prosthesis surgery.
title: Patología muscular No traumática No neoplásica
Creators: name: Carrera Terrón, Roberto
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Extremities
subject: Musculoskeletal soft tissue
subject: Musculoskeletal system
subject: MR
subject: CT
subject: Ultrasound
subject: Treatment effects
subject: Abscess
subject: Metabolic disorders
subject: Inflammation

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
1.Plantear una lecturasistemática de lapatología muscular no traumática y no tumoral mediante resonancia magnética (RM),
describiendo los principales patrones de afectación con los que nos podemos encontrar en la práctica cotidiana....
Supplementary document for Fabry-Perot effect and performance enhancement in magneto-optical InSb-based Terahertz Faraday isolator - 4931801.pdf
Creators: name: Keshock, Elise
name: Peng, Peisong
name: Zhou, Jiangfeng
name: Talbayev, Diyar
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplemental Document
title: Ictericia obstructiva con nombre propio: Síndrome de Lemmel
Creators: name: Gálvez García, Carlos
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Obstruction / Occlusion
subject: Inflammation
subject: Diverticula
subject: CT
subject: MR
subject: Fluoroscopy
subject: Abdomen

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
La diverticulosis duodenal es una entidad frecuente y que produce complicacionessólo en un pequeño porcentaje de los casos.
Éstas son principalmente la perforación y la hemorragia,
y otras menos frecuentes, la diverticulitis y la obstrucción de...