cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
МЕХАНИЗМЫ ОБЕСПЕЧЕНИЯ ЗАЩИТЫ ПОТРЕБИТЕЛЬСКИХ ПРАВ В СОЕДИНЕННЫХ ШТАТАХ АМЕРИКИ
Creators: name: Липка Д.В.
Publisher: name: Образование и право
Year: 2022
Subjects: потребитель
механизмы защиты прав потребителей в США
законодательство в сфере защиты прав потребителей в США.
Федеральная торговая комиссия США
общественные организации.

description: Статья посвящена исследованию государственных и негосударственных механизмов защиты прав потребителей в Соединенных Штатах Америки. В работе раскрыта деятельность правительственных организаций как: Федеральная торговая комиссия, Агентство финансовой защиты потребителей, Бюро экономики США, а также различных неправительственных организацией чьими задачами является представление и защита интересов потребителей.
НАЦИОНАЛЬНО-КУЛЬТУРНЫЕ ОБЪЕДИНЕНИЯ КАЗАХОВ ОМСКОЙ ОБЛАСТИ И СОХРАНЕНИЕ КАЗАХСКОГО КУЛЬТУРНОГО НАСЛЕДИЯ
Creators: name: Ильина А.А.
Publisher: name: Образование и право
Year: 2022
Subjects: казахи
национально-культурные объединения
культурное наследие
культура
казахский язык
Омская область.

description: Актуальность настоящего исследования связана с важностью сохранения культурного наследия всех этносов многонациональной Российской Федерации, в том числе одного из крупнейших этносов – казахского. Особая роль в выполнении данной задачи принадлежит национально-культурным объединениям. Первое национально-культурное объединение казахов было создано в Омской области – приграничном с Республикой Казахстан регионе, где казахи составляют значительную часть населения. Цель статьи – проследить деятельность национально-культурных объединений казахов Омской области по сохранению казахского культурного наследия. Рассматривается краткая история крупнейших национально-культурных объединений казахов Омской области, их цели и задачи, мероприятия, направленные на сохранение казахского культурного наследия и их результаты. Основной вывод заключается в существенной значимости деятельности национально-культурных объединений по сохранению казахского культурного наследия.
Chameleon attractors in a turbulent flow
Creators: name: Alberti, Tommaso
name: Daviaud, Francois
name: Donner, Reik V.
name: Dubrulle, Berengere
name: Faranda, Davide
name: Lucarini, Valerio
Publisher: name: arXiv
Year: 2021
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Turbulent flows present rich dynamics originating from non-trivial energy fluxes across scales, non-stationary forcings and geometrical constraints. This complexity manifests in non-hyperbolic chaos, randomness, state-dependent persistence and unpredictability. All these features have prevented a full characterization of the underlying turbulent (stochastic) attractor, which will be the key object to unpin this complexity. Here we propose a novel formalism to trace the evolution of the structural characteristics of phase-space trajectories across scales, providing a full characterization of the attractor. We demonstrate that the properties of the dynamically invariant objects depend on the scale we are focusing on. In the case of laboratory experiments on fluids we observe the emergence of an intrinsic timescale, solely determined by nonlinear interactions, controlling the geometrical and topological properties of phase-space trajectories. Given the changing nature of such attractors in time and scales we term them chameleon attractors.
description: 19 pages, 6 figures
Additional file 3 of Very small collars: an evaluation of telemetry location estimators for small mammals
Creators: name: Hummell, Grace F.
name: Li, Andrew Y.
name: Mullinax, Jennifer M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3. The amount of home range overlap (m2) produced by of the minimum convex polygon (MCP) and kernel density estimator (KDE) home ranges (n = 31) across three estimator programs (LOAS, LOCATE III, and Sigloc). The mice were tracked via micro-VHF collars in a suburban park in Howard county, Maryland, USA, 2018–2019.
ОБ АДМИНИСТРАТИВНО-ПРАВОВОЙ СУЩНОСТИ СЛУЖЕБНОЙ ДИСЦИПЛИНЫ В УГОЛОВНО-ИСПОЛНИТЕЛЬНОЙ СИСТЕМЕ
Creators: name: Чистяков К.А.
name: Бирмамитова С.А.
Publisher: name: Образование и право
Year: 2022
Subjects: служебная дисциплина
уголовно-исполнительная система
законность
административно-правовое содержание
дисциплинарная ответственность.

description: В статье рассматриваются теоретические и правовые вопросы, связанные с анализом содержания правого регулирования служебной дисциплины в уголовно-исполнительной системе.
ОБЕСПЕЧЕНИЕ ПРАВА РАБОТНИКОВ НА СПРАВЕДЛИВЫЕ УСЛОВИЯ ТРУДА, КАК ГАРАНТИЯ УВАЖЕНИЯ ЧЕЛОВЕКА ТРУДА
Creators: name: Соколова Т.В.
Publisher: name: Образование и право
Year: 2022
Subjects: Конституция РФ
уважение человека труда
право на труд
свобода труда
условия труда.

description: Принцип уважения человека труда является одним из важнейших принципов, заложенных в Конституцию РФ, а развитие государства и быстрый экономический рост связывают с повышением качества человеческих ресурсов. Однако, конституционные принципы, нуждаются в их детализации и конкретизации отраслевым законодательством. Автором рассматривается понятие человека труда, в том числе через право гражданина свободно распоряжаться способностями к труду, закрепленным в Конституции РФ (ст. ч. 1 ст. 37), а также реализация принципа уважения человека труда в трудовом законодательстве. Делается вывод, что этот принцип находит свое выражение в нормах, гарантирующих право работников на справедливые условия труда, в том числе на установление здоровых и безопасных условий труда, режима труда и времени отдыха и др.
J. H. Beynon: List of publications from John Herbert Beynon. 29 December 1923—24 August 2015
Creators: name: Boyd, Robert
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Organic Chemistry
subject: FOS: Chemical sciences

description: John Herbert Beynon was born in a Welsh mining village in 1923, graduated BSc (Hons, physics) at 19, then worked on weapons research for the war effort in World War Two. In 1947 he started a 22-year career at Imperial Chemical Industries (ICI) in Manchester, where, with his technician Albert Williams, he revolutionized mass spectrometry from a physics method to an essential technique for organic chemistry. In 1960 he completed his landmark book Mass spectrometry and its applications to organic chemistry, which was reprinted by the American Society for Mass Spectrometry as a ‘Classic Book’. He continued his creative work in 1969–1974 at Purdue University. In 1974 he started his Royal Society Research Professorship at Swansea University, his alma mater. Collaborations here with a long string of students, postdoc, visiting professors and scientists from many countries resulted in about 65% of his list of 395 peer-reviewed publications. His unexpected retirement led to a compendium of 32 articles in his honour. He then initiated and edited a new journal, Rapid Communications in Mass Spectrometry.
Universal critical behavior of the two-magnon-bound-state mass gap for the (2+1)-dimensional Ising model
Creators: name: Nishiyama, Yoshihiro
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The two-magnon-bound-state mass gap m_2 for the two-dimensional quantum Ising model was investigated by means of the numerical diagonalization method; the low-lying spectrum is directly accessible via the numerical diagonalization method. It has been claimed that the ratio m_2/m_1 (m_1: one-magnon mass gap) is a universal constant in the vicinity of the critical point. Aiming to suppress corrections to scaling (lattice artifact), we consider the spin-S=1 Ising model with finely-adjusted extended interactions. The simulation result for the finite-size cluster with N \le 20 spins indicates the mass-gap ratio m_2/m_1=1.84(1).
О ПОДГОТОВКЕ СОЦИАЛЬНЫХ РАБОТНИКОВ И ДРУГИХ СПЕЦИАЛИСТОВ ПО СОЦИАЛЬНОЙ ЗАЩИТЕ В КЫРГЫЗСКОЙ РЕСПУБЛИКЕ
Creators: name: Суйуналиева Б.Ш.
name: Атабекова Н.К.
name: Ураимова Т.А.
name: Абдуганиев К.А.
name: Сапаралиева Г.Н.
Publisher: name: Образование и право
Year: 2022
Subjects: социальная работа
высшие учебные заведения
средние специальные учебные заведения
социальный работник
дуальное обучение
практика.

description: В статье рассмотрены вопросы подготовки кадров в сфере социальной защиты, проведен анализ подготовки социальных работников и других специалистов по социальной защите в высших и средних учебных заведениях Кыргызской Республики. Целью работы является изучение существующей национальной системы подготовки кадров в сфере социальной защиты и выявление проблем процесса подготовки специалистов социальной работы. В работе использованы методы анализа, синтеза для выявления проблем в сфере подготовки кадров социальной защиты, статистический метод для изучения динамики роста количества образовательных учреждений, осуществляющих подготовку кадров в указанной и смежной сферах. Исследование базировалось на данных аналитического отчета, подготовленного в рамках мезауровня проекта «Консолидация структур РУО в Таджикистане, Кыргызстане и Узбекистане и дальнейшей профессионализации обучения социальной работе с применением подхода РУО», реализуемого ОФ «Фонд развития социальных услуг» в Кыргызской Республике.Авторами выработаны рекомендации по совершенствованию национальной системы подготовки кадров по социальной работе в системе профессионального образования страны.
Half-Monopole in the Weinberg-Salam Model
Creators: name: Teh, Rosy
name: Ng, Ban-Loong
name: Wong, Khai-Ming
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present new axially symmetric half-monopole configuration of the SU(2)$\times$U(1) Weinberg-Salam model of electromagnetic and weak interactions. The half-monopole configuration possesses net magnetic charge $2π/e$ which is half the magnetic charge of a Cho-Maison monopole. The electromagnetic gauge potential is singular along the negative $z$-axis. However the total energy is finite and increases only logarithmically with increasing Higgs field self-coupling constant $λ^{1/2}$ at $\sin^2θ_W=0.2312$. In the U(1) magnetic field, the half-monopole is just a one dimensional finite length line magnetic charge extending from the origin $r=0$ and lying along the negative $z$-axis. In the SU(2) 't Hooft magnetic field, it is a point magnetic charge located at $r=0$. The half-monopole possesses magnetic dipole moment that decreases exponentially fast with increasing Higgs field self-coupling constant $λ^{1/2}$ at $\sin^2θ_W=0.2312$.
description: 14 pages, 3 Figures
Coupling and Electrical Control of Structural, Orbital and Magnetic Orders in Perovskites
Creators: name: Varignon, Julien
name: Bristowe, Nicholas C.
name: Bousquet, Eric
name: Ghosez, Philippe
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Perovskite oxides are already widely used in industry and have huge potential for novel device applications thanks to the rich physical behaviour displayed in these materials. The key to the functional electronic properties exhibited by perovskites is often the so-called Jahn-Teller distortion. For applications, an electrical control of the Jahn-Teller distortions, which is so far out of reach, would therefore be highly desirable. Based on universal symmetry arguments, we determine new lattice mode couplings that can provide exactly this paradigm, and exemplify the effect from first-principles calculations. The proposed mechanism is completely general, however for illustrative purposes, we demonstrate the concept on vanadium based perovskites where we reveal an unprecedented orbital ordering and Jahn-Teller induced ferroelectricity. Thanks to the intimate coupling between Jahn-Teller distortions and electronic degrees of freedom, the electric field control of Jahn-Teller distortions is of general relevance and may find broad interest in various functional devices.
description: The first two authors contributed equally
Potentiator ivacaftor abrogates pharmacological correction of  F508 CFTR in cystic fibrosis
Creators: name: Randell, S. H.
name: Cholon, D. M.
name: Quinney, N. L.
name: Boucher, R. C.
name: Esther, C. R.
name: Das, J.
name: Dokholyan, N. V.
name: Fulcher, M. L.
name: Gentzsch, M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Cystic Fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR). Newly developed “correctors” such as lumacaftor (VX-809) that improve CFTR maturation and trafficking and “potentiators” such as ivacaftor (VX-770) that enhance channel activity may provide important advances in CF therapy. Although VX-770 has demonstrated substantial clinical efficacy in the small subset of patients with a mutation (G551D) that affects only channel activity, a single compound is not sufficient to treat patients with the more common CFTR mutation, ΔF508. Thus, patients with ΔF508 will likely require treatment with both correctors and potentiators to achieve clinical benefit. However, whereas the effectiveness of acute treatment with this drug combination has been demonstrated in vitro, the impact of chronic therapy has not been established. In studies of human primary airway epithelial cells, we found that both acute and chronic treatment with VX-770 improved CFTR function in cells with the G551D mutation, consistent with clinical studies. In contrast, chronic VX-770 administration caused a dose-dependent reversal of VX-809-mediated CFTR correction in ΔF508 homozygous cultures. This result reflected the destabilization of corrected ΔF508 CFTR by VX-770, dramatically increasing its turnover rate. Chronic VX-770 treatment also reduced mature wild-type CFTR levels and function. These findings demonstrate that chronic treatment with CFTR potentiators and correctors may have unexpected effects that cannot be predicted from short-term studies. Combining of these drugs to maximize rescue of ΔF508 CFTR may require changes in dosing and/or development of new potentiator compounds that do not interfere with CFTR stability.
Additional file 4 of Very small collars: an evaluation of telemetry location estimators for small mammals
Creators: name: Hummell, Grace F.
name: Li, Andrew Y.
name: Mullinax, Jennifer M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 4. Perimeter area ratio for kernel density estimator (KDE) home ranges (n = 31) across three estimator programs (LOAS, LOCATE III, and Sigloc). The mice were tracked via micro-VHF collars in a suburban park in Howard county, Maryland, USA, 2018–2019.
Temperature and phase dynamics in superconducting weak-link
Creators: name: Gupta, Anjan K.
name: Kumar, Nikhil
name: Biswas, Sourav
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: A time dependent thermal model for a superconducting constriction based weak-link (WL) is discussed for investigating the deterministic dynamics of its temperature and phase. A new dynamic regime is found where a non-zero voltage exists across the WL and its temperature stabilizes between the bath temperature and superconductor's critical temperature. This regime exists over a limited bias current range and gives rise to a new hysteretic regime in current-voltage characteristics. We also discuss the effect of fluctuations on the current-voltage characteristics and experimental implications of this dynamic regime.
description: 7 pages, 4 figures; revised on 25 Nov 2014
О ПРАВИЛАХ ОСУЩЕСТВЛЕНИЯ ГРАЖДАНАМИ АУДИОИ ВИДЕОЗАПИСИ В ХОДЕ ЛИЧНОГО ПРИЕМА В ОРГАНАХ ГОСУДАРСТВЕННОЙ ВЛАСТИ, ОРГАНАХ МЕСТНОГО САМОУПРАВЛЕНИЯ
Creators: name: Усов А.Ю.
Publisher: name: Образование и право
Year: 2022
Subjects: личный прием
право на изображение
право на информацию
гласность
открытость деятельности
аудиозапись
видеозапись
цифровизация
должностное лицо
органы государственной власти
органы местного самоуправления.

description: Цифровизация является одной из тенденций развития современного общества, оказывающей влияние и на процесс взаимодействия граждан и органов власти. В теории и на практике нередко возникают вопросы о возможностях и пределах использования современных технологий в этой сфере, одним из проявлений которых является возможность осуществления аудиои видеофиксации в ходе личного приема в органах публичной власти. В последнее время в общественном сознании появляется стойкое убеждение в том, что у граждан есть право свободно, без какого-либо предварительного уведомления осуществлять аудиозапись, фото-, видеоили киносъемку в ходе взаимодействия с органами публичной власти, в том числе – во время личного приема. Возникающие споры в этой сфере нередко становятся предметом рассмотрения судов, в частности, в тех случаях, когда гражданину отказывают в личном приеме в связи с тем, что он предпринимает попытки осуществить аудиоили видеозапись должностного лица без предварительного разрешения. Рассмотрение судами таких дел почти всегда сопровождается разрешением вопроса о том, является ли полученная запись допустимым доказательством, и при соблюдении каких условий такая запись будет иметь доказательственное значение. На основе анализа нормативных правовых актов, судебных решений и научных трудов по данной проблематике автор приходит к выводу о необходимости внесения изменений в Федеральный закон от 02.05.2006 № 59-ФЗ «О порядке рассмотрения обращений граждан Российской Федерации» в целях определения правил осуществления гражданами аудиои видеозаписи в ходе личного приема.
Exact diagonalization study of the spin-1 two-dimensional $J_1$-$J_3$ Heisenberg model on a triangular lattice
Creators: name: Rubin, P.
name: Sherman, A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The spin-1 Heisenberg model on a triangular lattice with the ferromagnetic nearest- and antiferromagnetic third-nearest-neighbor exchange interactions, $J_1=-(1-p)J$ and $J_2=pJ$, $J>0$ $ (0 \leq p \leq 1)$, is studied with the use of the SPINPACK code. This model is applicable for the description of the magnetic properties of NiGa$_2$S$_4$. The ground, low-lying excited state energies and spin-spin correlation functions have been found for lattices with N=16 and N=20 sites with the periodic boundary conditions. These results are in qualitative agreement with earlier authors' results obtained with Mori's projection operator technique.
description: 5 pages, 6 figures
Local Advantage Networks for Cooperative Multi-Agent Reinforcement Learning
Creators: name: Avalos, Raphaël
name: Reymond, Mathieu
name: Nowé, Ann
name: Roijers, Diederik M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Many recent successful off-policy multi-agent reinforcement learning (MARL) algorithms for cooperative partially observable environments focus on finding factorized value functions, leading to convoluted network structures. Building on the structure of independent Q-learners, our LAN algorithm takes a radically different approach, leveraging a dueling architecture to learn for each agent a decentralized best-response policies via individual advantage functions. The learning is stabilized by a centralized critic whose primary objective is to reduce the moving target problem of the individual advantages. The critic, whose network's size is independent of the number of agents, is cast aside after learning. Evaluation on the StarCraft II multi-agent challenge benchmark shows that LAN reaches state-of-the-art performance and is highly scalable with respect to the number of agents, opening up a promising alternative direction for MARL research.
description: https://openreview.net/forum?id=adpKzWQunW
ОСНОВНЫЕ НАПРАВЛЕНИЯ УЧАСТИЯ ОРГАНОВ ВНУТРЕННИХ ДЕЛ В СИСТЕМЕ КИБЕРБЕЗОПАСНОСТИ
Creators: name: Комаревцева И.В.
Publisher: name: Образование и право
Year: 2022
Subjects: исторический анализ
правоохранительные органы
полиция
кибербезопасность
направления деятельности полиции.

description: В данном исследовании предпринята попытка краткого исследование деятельности органов внутренних дел по обеспечению кибербезопасности в Российской Федерации. Достижению указанной цели будет способствовать решение следующей задач исследования как выявление основных направлений деятельности органов внутренних дел в системе обеспечения кибербезопасности. Изучение истории создания и основных направлений деятельности профильного подразделения МВД России отражают совокупность взаимодействия внутреннего и внешнего направлений деятельности полиции в области кибербезопасности.
A Wolf-Rayet-like progenitor of supernova SN 2013cu from spectral observations of a wind
Creators: name: Gal-Yam, Avishay
name: Arcavi, I.
name: Ofek, E. O.
name: Ben-Ami, S.
name: Cenko, S. B.
name: Kasliwal, M. M.
name: Cao, Y.
name: Yaron, O.
name: Tal, D.
name: Silverman, J. M.
name: Horesh, A.
name: De Cia, A.
name: Taddia, F.
name: Sollerman, J.
name: Perley, D.
name: Vreeswijk, P. M.
name: Kulkarni, S. R.
name: Nugent, P. E.
name: Filippenko, A. V.
name: Wheeler, J. C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The explosive fate of massive stripped Wolf-Rayet (W-R) stars is a key open question in stellar physics. An appealing option is that hydrogen-deficient W-R stars are the progenitors of some H-poor supernova (SN) explosions of Types IIb, Ib, and Ic. A blue object, having luminosity and colors consistent with those of some W-R stars, has been recently identified at the location of a SN~Ib in pre-explosion images but has not yet been conclusively determined to have been the progenitor. Similar previous works have so far only resulted in nondetections. Comparison of early photometric observations of Type Ic supernovae with theoretical models suggests that the progenitor stars had radii <10^12 cm, as expected for some W-R stars. However, the hallmark signature of W-R stars, their emission-line spectra, cannot be probed by such studies. Here, we report the detection of strong emission lines in an early-time spectrum of SN 2013cu (iPTF13ast; Type IIb) obtained ~15.5 hr after explosion ("flash spectroscopy"). We identify W-R-like wind signatures suggesting a progenitor of the WN(h) subclass. The extent of this dense wind may indicate increased mass loss from the progenitor shortly prior to its explosion, consistent with recent theoretical predictions.
description: Nature, Volume 509, Issue 7501, pp. 471-474 (2014). Author version prior to final editing to conform to Journal style; includes extended data figures and methods; see final official version at http://www.nature.com/nature/journal/v509/n7501/full/nature13304.html
Cytomegalovirus infection enhances the immune response to influenza
Creators: name: Thomas, Paul G.
name: Furman, David
name: Sharma, Shalini
name: Dekker, Cornelia L.
name: Kidd, Brian A.
name: Shen-Orr, Shai S.
name: Concannon, Patrick
name: Davis, Mark M.
name: Jojic, Vladimir
name: L. Angel, Cesar J.
name: Maecker, Holden T.
name: Onengut-Gumuscu, Suna
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Cytomegalovirus (CMV) is a beta-herpes virus present in a latent form in most people worldwide. In immunosuppressed individuals, CMV can reactivate and cause serious clinical complications, but the effect of the latent state on healthy people remains elusive. We undertook a systems approach to understand the differences between seropositive and negative subjects and measured hundreds of immune system components from blood samples including cytokines and chemokines, immune cell phenotyping, gene expression, ex vivo cell responses to cytokine stimuli and the antibody response to seasonal influenza vaccination. As expected, we found decreased responses to vaccination and an overall down-regulation of immune components in aged individuals regardless of CMV serostatus. In contrast, CMV-infected young adults exhibited an overall up-regulation of immune components including enhanced antibody responses to influenza vaccination, increased CD8+ T cell sensitivity, and elevated levels of circulating IFN-γ compared to uninfected individuals. Experiments with young mice infected with murine CMV also showed significant protection from an influenza virus challenge compared with uninfected animals, although this effect declined with time. These data show that CMV and its murine equivalent can have a beneficial effect on the immune response of young, healthy individuals, which may explain the continued coexistence of CMV and mammals throughout their evolution.
Additional file 1 of Reduced graphene oxide-based nanometal-composite containing copper and silver nanoparticles protect tomato and pepper against Xanthomonas euvesicatoria infection
Creators: name: Bytešníková, Zuzana
name: Pečenka, Jakub
name: Tekielska, Dorota
name: Kiss, Tomáš
name: Švec, Pavel
name: Ridošková, Andrea
name: Bezdička, Petr
name: Pekárková, Jana
name: Eichmeier, Aleš
name: Pokluda, Robert
name: Adam, Vojtěch
name: Richtera, Lukáš
Publisher: name: figshare
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 1: Fig S1. AFM image of GO. Fig S2. SEM image of rGO-Ag (A) and rGO-Cu (B) nanocomposites. Fig S3. Elemental mapping confirming the presence of the silver in the rGO-Ag (A) and copper in the rGO-Cu (B). Fig S4. FTIR spectra of GO and rGO-Cu-Ag nanocomposite. Table S1. cDNAs used for real-time PCR. Table S2. Antibacterial effect of nanomaterials on X. euvesicatoria growth. Results based on colony forming unit enumeration shown as the bacterial growth in percent from non-treated control which was 100%.
Impact of guidance documents on translational large animal studies of cartilage repair
Creators: name: Pfeifer, Christian G.
name: Carey, James L.
name: Fisher, Matthew B.
name: Mauck, Robert L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Promising therapies for cartilage repair are translated through large animal models toward human application. To guide this work, regulatory agencies publish recommendations (“guidance documents”) to direct pivotal large animal studies. These are meant to aid in study design, outline metrics for judging efficacy, and facilitate comparisons between studies. To determine the penetrance of these documents in the field, we synthesized the recommendations of the American Society for Testing and Materials, U.S. Food and Drug Administration, and European Medicines Agency into a scoring system and performed a systematic review of the past 20 years of preclinical cartilage repair studies. Our hypothesis was that the guidance documents would have a significant impact on how large animal cartilage repair studies were performed. A total of 114 publications meeting our inclusion criteria were reviewed for adherence to 24 categories extracted from the guidance documents, including 11 related to study design and description and 13 related to study outcomes. Overall, a weak positive trend was observed over time (P=0.004, R2=0.07, slope=0.63%/year), with overall adherence (the sum of study descriptors and outcomes) ranging from 32±16% to 58±14% in any individual year. There was no impact of the publication of the guidance documents on adherence (P =0.264 to 0.50). Given that improved adherence would expedite translation, we discuss the reasons for poor adherence and outline approaches to increase and promote their more widespread adoption.
title: Voiding urosonography (VUS) using a second-generation US contrast agent vs voiding cystourethrography in VUR detection and grading: a retrospective study.
Creators: name: Costanzo, Vincenzo
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Paediatric
subject: Urinary Tract / Bladder
subject: Contrast agents
subject: Ultrasound
subject: Digital radiography
subject: Cystography / Uretrography
subject: Contrast agent-other
subject: Comparative studies
subject: Infection

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: VUR is a common disorder in children that leads to ascending infection, renal growth impairment and parenchymal scarring; the reflux nephropathy is responsible for 30-50% of renal failure in children. [1-4] Primary VUR is the most common congenital...
Compact formulas for bounce/transit averaging in axisymmetric tokamak geometry
Creators: name: Duthoit, F. -X.
name: Brizard, A. J.
name: Hahm, T. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Compact formulas for bounce and transit orbit averaging of the fluctuation-amplitude eikonal factor in axisymmetric tokamak geometry, which is frequently encountered in bounce-gyrokinetic description of microturbulence, are given in terms of the Jacobi elliptic functions and elliptic integrals. These formulas are readily applicable to the calculation of the neoclassical susceptibility in the framework of modern bounce-gyrokinetic theory. In the long-wavelength limit for axisymmetric electrostatic perturbations, we recover the expression for the Rosenbluth-Hinton residual zonal flow [Rosenbluth and Hinton, Phys.~Rev.~Lett.~{\bf 80}, 724 (1998)] accurately.
description: 10 pages, 8 figures
Additional file 1 of Efficacy and safety of adrenergic alpha-1 receptor antagonists in older adults: a systematic review and meta-analysis supporting the development of recommendations to reduce potentially inappropriate prescribing
Creators: name: Mansbart, Felix
name: Kienberger, Gerda
name: Sönnichsen, Andreas
name: Mann, Eva
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1. Search terms used in the literature database search.
Accretion-Inhibited Star Formation in the Warm Molecular Disk of the Green-valley Elliptical Galaxy NGC 3226
Creators: name: Appleton, P. N.
name: Mundell, C.
name: Bitsakis, T.
name: Lacy, M.
name: Alatalo, K.
name: Armus, L.
name: Charmandaris, V.
name: Duc, P. -A.
name: Lisenfeld, U.
name: Ogle, P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present archival Spitzer photometry and spectroscopy, and Herschel photometry, of the peculiar "Green Valley" elliptical galaxy NGC~3226. The galaxy, which contains a low-luminosity AGN, forms a pair with NGC~3227, and is shown to lie in a complex web of stellar and HI filaments. Imaging at 8 and 16$μ$m reveals a curved plume structure 3 kpc in extent, embedded within the core of the galaxy, and coincident with the termination of a 30 kpc-long HI tail. In-situ star formation associated with the IR plume is identified from narrow-band HST imaging. The end of the IR-plume coincides with a warm molecular hydrogen disk and dusty ring, containing 0.7-1.1 $\times$ 10$^7$ M$_{\odot}$ detected within the central kpc. Sensitive upper limits to the detection of cold molecular gas may indicate that a large fraction of the H$_2$ is in a warm state. Photometry, derived from the UV to the far-IR, shows evidence for a low star formation rate of $\sim$0.04 M$_{\odot}$ yr$^{-1}$ averaged over the last 100 Myrs. A mid-IR component to the Spectral Energy Distribution (SED) contributes $\sim$20$\%$ of the IR luminosity of the galaxy, and is consistent with emission associated with the AGN. The current measured star formation rate is insufficient to explain NGC3226's global UV-optical "green" colors via the resurgence of star formation in a "red and dead" galaxy. This form of "cold accretion" from a tidal stream would appear to be an inefficient way to rejuvenate early-type galaxies, and may actually inhibit star formation.
description: Accepted for Publication ApJ Oct 2014
О ПРАВОВОМ РЕГУЛИРОВАНИИ ДОГОВОРА КУПЛИ-ПРОДАЖИ АКЦИЙ
Creators: name: Сказин Н.А.
name: Калюжная П.Л.
name: Пугина В.И.
Publisher: name: Образование и право
Year: 2022
Subjects: договор купли-продажи
акция
соглашение сторон
государственная регистрация
эмиссия акций
существенные условия договора.

description: Данная статья посвящена исследованию договора купли-продажи акций в гражданском праве и законодательстве. В работе проведен анализ норм регулирующих особенности купли-продажи акций и их практическая реализация. Авторами поднимается проблема отсутствия полноценного правового регулирования данного вида договора и предлагаются пути решения данной проблемы путем восполнения пробелов законодательства.
title: Combined CT-guided percutaneous byopsia, radiofrequency thermoablation and vertebroplasty: our experience in the treatment of dorsolumbar metastases.
Creators: name: Costanzo, Vincenzo
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Bones
subject: Interventional non-vascular
subject: Neuroradiology spine
subject: CT
subject: Fluoroscopy
subject: Ablation procedures
subject: Biopsy
subject: Vertebroplasty
subject: Metastases

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The most frequent site of bone metastasis is the vertebrae, likely related to the high hematopoietic activity and vascularization of the spine. Most of the times first the posterior part of the vertebral body is invaded. Spine metastases can lead to...
Liver-directed lentiviral gene therapy in a dog model of hemophilia B
Creators: name: Schmidt, Manfred
name: Martin, Samia
name: Doglioni, Claudio
name: Gallina, Pierangela
name: Sanvito, Francesca
name: Bartholomae, Cynthia C.
name: Chuah, Marinee K.
name: Ranzani, Marco
name: Merricks, Elizabeth
name: Volpin, Monica
name: Valle, Patrizia Della
name: Cantore, Alessio
name: Bellintani, Francesca
name: Bellinger, Dwight
name: D’Angelo, Armando
name: VandenDriessche, Thierry
name: Montini, Eugenio
name: Raymer, Robin
name: Sergi, Lucia Sergi
name: Benedicenti, Fabrizio
name: Nichols, Timothy
name: Naldini, Luigi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: We investigated the safety and efficacy of liver-directed gene therapy using lentiviral vectors in a large animal model of hemophilia B, and evaluated the risk of insertional mutagenesis in tumor-prone mouse models. We show that gene therapy using lentiviral vectors targeting expression of a canine factor IX transgene to hepatocytes was well-tolerated and provided stable long-term production of coagulation factor IX in dogs with hemophilia B. By exploiting three different mouse models designed to amplify the consequences of insertional mutagenesis, we show that no genotoxicity was detected with these lentiviral vectors. Our findings suggest that lentiviral vectors may be an attractive candidate for gene therapy targeted to the liver and may be useful for the treatment of hemophilia.
Additional file 2 of Efficacy and safety of adrenergic alpha-1 receptor antagonists in older adults: a systematic review and meta-analysis supporting the development of recommendations to reduce potentially inappropriate prescribing
Creators: name: Mansbart, Felix
name: Kienberger, Gerda
name: Sönnichsen, Andreas
name: Mann, Eva
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 2. Reasons for exclusion in full text analysis.
Local iontophoretic administration of cytotoxic therapies to solid tumors
Creators: name: Anders, Carey K.
name: Napier, Mary E.
name: Brooks, Christopher R.
name: Bickford, Lissett R.
name: Deal, Allison
name: Stack, Richard
name: Wang, Andrew Z.
name: O’Neill, Adrian T.
name: Tepper, Joel E.
name: Hyder, Nabeel
name: Luft, J. Chris
name: DeSimone, Joseph M.
name: Zamboni, William C.
name: Lee, William
name: Wagner, Kyle
name: Nelson, Meredith
name: Keeler, Amanda W.
name: Little, Ryan E.
name: Moffitt, Richard A.
name: Darr, David
name: R. Jajja, Mohammad N.
name: Byrne, James D.
name: Yeh, Jen Jen
name: Stack, Colleen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Parenteral and oral routes have been the traditional methods of administering cytotoxic agents to cancer patients. Unfortunately, the maximum potential effect of these cytotoxic agents has been limited because of systemic toxicity and poor tumor perfusion. In an attempt to improve the efficacy of cytotoxic agents while mitigating their side effects, we have developed modalities for the localized iontophoretic delivery of cytotoxic agents. These iontophoretic devices were designed to be implanted proximal to the tumor with external control of power and drug flow. Three distinct orthotopic mouse models of cancer and a canine model were evaluated for device efficacy and toxicity. Orthotopic patient-derived pancreatic cancer xenografts treated biweekly with gemcitabine via the device for 7 weeks experienced a mean log2 fold change in tumor volume of −0.8 compared to a mean log2 fold change in tumor volume of 1.1 for intravenous (IV) gemcitabine, 3.0 for IV saline, and 2.6 for device saline groups. The weekly coadministration of systemic cisplatin therapy and transdermal device cisplatin therapy significantly increased tumor growth inhibition and doubled the survival in two aggressive orthotopic models of breast cancer. The addition of radiotherapy to this treatment further extended survival. Device delivery of gemcitabine in dogs resulted in more than 7-fold difference in local drug concentrations and 25-fold lower systemic drug levels than the IV treatment. Overall, these devices have potential paradigm shifting implications for the treatment of pancreatic, breast, and other solid tumors.
ОСОБЕННОСТИ АДМИНИСТРАТИВНОЙ ПРОЦЕССУАЛЬНОЙ ФОРМЫ ЗАЩИТЫ ПУБЛИЧНЫХ ПРАВ
Creators: name: Ломаченко Е.В.
Publisher: name: Образование и право
Year: 2022
Subjects: административное судопроизводство
производство по делам об административных правонарушений
процессуальная форма
административные и иные.

description: В данной статье предметом исследования является проблематика отсутствия в действующем законодательстве отдельного обособления административной процессуальной формы, при этом сам публично-правовой характер предполагает ее специфику и фактическую применяемость. Также в научной статье обозначаются многие несоответствия положений Кодекса административного судопроизводства Российской Федерации правовой природе публичных правоотношений. В исследовании рассматривается вопрос об особенностях публичных правоотношений, критерии отграничения их от гражданских правоотношений, а также обознается проблематика отсутствия в действующем законе терминологии раскрывающей сущность административного спора. Показана связь процессуальных правил рассмотрения правовых конфликтов судом с сущностью тех правоотношений, из которых возник спор. Автором по анализируемым несоответствиям действующего закона предлагаются соответствующие теоретические пути разрешения правовых пробелов. Определено, что в настоящее время большое количество дел, которые по своей сущности являются, не чем иным как административным спором, рассматриваются по правилам искового производства, хотя должны бы быть предметом административного судопроизводства, к таким можно отнести: а) дела о принудительном изъятии земельных участков для государственных и муниципальных нужд, б) споры, возникающие в процессе заключения и исполнения государственных контрактов, пенсионного обеспечения граждан и т.п. Обозначено, что в силу своей публично-правовой природы они должны быть предметом административного производства. В исследовании сделан вывод о том, что действующий Кодекс административного судопроизводства Российской Федерации требует соответствующей переработки, которая заключается в: а) обособление административного судопроизводства и б) отдельного обозначение и выделения специфики административной процессуальной формы.
Additional file 1 of Hepatitis B virus suppresses complement C9 synthesis by limiting the availability of transcription factor USF-1 and inhibits formation of membrane attack complex: implications in disease pathogenesis
Creators: name: Baidya, Ayana
name: Khatun, Mousumi
name: Mondal, Rajiv Kumar
name: Ghosh, Suchandrima
name: Chakraborty, Bidhan Chandra
name: Mallik, Shreya
name: Ahammed, S. K. Mahiuddin
name: Chowdhury, Abhijit
name: Banerjee, Soma
name: Datta, Simanti
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1. Table S1. List of primers used for amplification, sequencing and cloning of HBV. Table S2. List of primers and oligos targeting host genes and promoters. Table S3. Clinical, demographic and biochemical data of the study subjects. Fig S1. Relative mRNA expression of USF-1 in HBx transfected Huh7 cells treated with or without histone deacetylation inhibitor Trichostatin A (0.1μM).
Physical properties, kinetics and mass function of 12 northern infrared dark clouds
Creators: name: Liu, Xiao-Lan
name: Wang, Jun-Jie
name: Xu, Jin-Long
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The physical, chemical and kinetic characteristics of 12 northern infrared dark clouds (IRDCs) are systematic studied using the $\rm ^{13}CO $ (1-0) and $\rm C^{18}O$ (1-0) lines, observed with the PMO 13.7 m radio telescope, the 1.1 mm Bolocam Galactic Plane Survey (BGPS) data and GLIMPSE Spitzer IRAC $\rm 8 \,μm$ data. The molecular lines emission and 1.1 mm continuum emission almost coincide in morphology for each IRDC and both are associated well with the IRDCs. 10 IRDCs present the filamentary structure and substructures. Totally, 41 IRDC cores are identified and a statistic research for them shows that the northern IRDC cores have a typical excitation temperature $8\sim10$ K, a integrated intensity ratio of $\rm ^{13}CO$ to $\rm C^{18}O$ $3\sim6$ and the column density $(1\sim6)\times 10^{22}\, \rm cm^{-2}$. About $57.5\%$ of the IRDC cores are gravitationally bound, which are more compact, warmer and denser. In addition, we study the mass distribution functions of the whole IRDC cores as well as the gravitational bound cores, finding that they almost have the same power-law indexes. This indicates that the evolution of the IRDC cores almost have no effect on the mass spectrum of the molecular cores and thus can be used to study the stellar initial mass function. Moreover, three IRDC cores G24.00-3, G31.38-1 and G34.43-4 are detected to have large-scaled infall motions. Two different outflows are further found for IRDC core G34.43-4 and one of them is in high collimation.
description: 24 pages, 2 tables
Meridional energy transport extremes and the general circulation of Northern Hemisphere mid-latitudes: dominant weather regimes and preferred zonal wavenumbers
Creators: name: Lembo, Valerio
name: Fabiano, Federico
name: Galfi, Vera Melinda
name: Graversen, Rune
name: Lucarini, Valerio
name: Messori, Gabriele
Publisher: name: arXiv
Year: 2021
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Fluid Dynamics (physics.flu-dyn)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: The extratropical meridional energy transport in the atmosphere is fundamentally intermittent in nature, having extremes large enough to affect the net seasonal transport. Here, we investigate how these extreme transports are associated with the dynamics of the atmosphere at multiple spatial scales, from planetary to synoptic. We use the ERA5 reanalysis data to perform a wavenumber decomposition of meridional energy transport in the Northern Hemisphere mid-latitudes during winter and summer. We then relate extreme transport events to atmospheric circulation anomalies and dominant weather regimes, identified by clustering 500hPa geopotential height fields. In general, planetary-scale waves determine the strength and meridional position of the synoptic-scale baroclinic activity with their phase and amplitude, but important differences emerge between seasons. During winter, large wavenumbers ($k=2-3$) are key drivers of the meridional energy transport extremes, and planetary and synoptic-scale transport extremes virtually never co-occur. In summer, extremes are associated with higher wavenumbers ($k=4-6$), identified as synoptic-scale motions. We link these waves and the transport extremes to recent results on exceptionally strong and persistent co-occurring summertime heat waves across the Northern Hemisphere mid-latitudes. We show that the weather regime structures associated with these heat wave events are typical for extremely large poleward energy transport events.
description: 40 pages, 17 figures