cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on human cytomegalovirus replication in vitro.
Creators: name: Mar, E C
name: Cheng, Y C
name: Huang, E S
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: We studied the effect of a novel purine acyclic nucleoside, 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG), on human cytomegalovirus (HCMV) replication. The susceptibility of HCMV to this drug was monitored in cell culture by plaque reduction assay. HCMV replication of various strains was inhibited to the extent of 50% by 1 to 5 microM DHPG. DHPG was highly specific in its anti-HCMV activity, since at concentrations as high as 100 microM it did not exert any detectable inhibitory effect on uninfected cell macromolecular synthesis and cell growth. At concentrations of 2 to 4 microM, the drug inhibited the synthesis of six virus-specific polypeptides with molecular weights of 200,000 (VP200), 150,000 (VP150), 67,000 (VP67), 54,000 (VP54), 32,000 (VP32), and 27,000 (VP27) up to 96 h after infection. HCMV DNA synthesis was also considerably suppressed at concentrations of 2 to 4 microM DHPG. Upon removal of the inhibitor, however, viral DNA synthesis resumed and infectious virus reappeared, indicating that this inhibition was a virostatic reversible-type inhibition.
Calibration of the Hα age–activity relation for M dwarfs
Creators: name: Rice, E.
name: Bardalez Gagliuffi, D.C.
name: Faherty, J.K.
name: Angus, R.
name: Gagné, J.
name: Cruz, K.L.
name: Schmidt, S.J.
name: Kiman, R.
name: Mann, A.W.
Publisher: name: American Astronomical Society
Year: 2021

description: In this work, we calibrate the relationship between Hα emission and M dwarf ages. We compile a sample of 892 M dwarfs with Hα equivalent width (Hα EW) measurements from the literature that are either comoving with a white dwarf of known age (21 stars) or in a known young association (871 stars). In this sample we identify 7 M dwarfs that are new candidate members of known associations. By dividing the stars into active and inactive categories according to their Hα EW and spectral type (SpT), we find that the fraction of active dwarfs decreases with increasing age, and the form of the decline depends on SpT. Using the compiled sample of age calibrators, we find that Hα EW and fractional Hα luminosity (LHα/Lbol) decrease with increasing age. Hα EW for SpT ≼ M7 decreases gradually up until ∼1 Gyr. For older ages, we found only two early M dwarfs that are both inactive and seem to continue the gradual decrease. We also found 14 mid-type M dwarfs, out of which 11 are inactive and present a significant decrease in Hα EW, suggesting that the magnetic activity decreases rapidly after ∼1 Gyr. We fit LHα/Lbol versus age with a broken power law and find an index of -0.11-0.01+0.02 for ages ≾776 Myr. The index becomes much steeper at older ages, but a lack of field age-calibrators (≫1 Gyr) leaves this part of the relation far less constrained. Finally, from repeated independent measurements for the same stars, we find that 94% of them have a level of Hα EW variability ≼5 Å at young ages (<1 Gyr).
title: Visiting Ancient Rome with a Serious Game
Creators: name: Galí, Carlos
name: Remolar, Inmaculada
name: Rebollo, Cristina
Publisher: name: The Eurographics Association
Year: 2019
Subjects: Applied computing
Interactive learning environments
Software and its engineering
Interactive games

description: The current rise of video games has made that different fields of research feel attracted to these new technologies in order to enhance their works and make their results more attractive. It is for this reason that so-called serious games have arisen, with different purposes than leisure. Related to this topic, this article presents a serious game that allows the user to build historical cities dated in the ancient Roman era. The game reproduces as accurately as possible the different buildings and constructions of the time, making it possible for the player to create Roman cities in a simple way. Once they are already built, the user can visit them, access to the buildings and be able to interact with the objects and characters that appear. This video game has been addressed to the education field and, to evaluate its quality and usability, several experiments have been carried out taking as sample high school students. Initially, the playability of this serious game has been evaluated and, subsequently, the motivation of the game in learning history. The results obtained support on the one hand the gameplay and attractiveness of the video game, and on the second hand, the increase of the interest of the students in the learning of the history, as well as the greater fixation of different concepts treated in this video game.
description: Spanish Computer Graphics Conference (CEIG)
description: Short Papers
description: 77
description: 80
description: Carlos Galí, Inmaculada Remolar, and Cristina Rebollo
description: CCS Concepts: Applied computing--> Interactive learning environments; Software and its engineering--> Interactive games
Inflationary gravitational waves in the effective field theory of modified gravity
Creators: name: De Felice, Antonio
name: Tsujikawa, Shinji
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the approach of the effective field theory of modified gravity, we derive the second-order action and the equation of motion for tensor perturbations on the flat isotropic cosmological background. This analysis accommodates a wide range of gravitational theories including Horndeski theories, its generalization, and the theories with spatial derivatives higher than second order (e.g., Horava-Lifshitz gravity). We obtain the inflationary power spectrum of tensor modes by taking into account corrections induced by higher-order spatial derivatives and slow-roll corrections to the de Sitter background. We also show that the leading-order spectrum in concrete modified gravitational theories can be mapped on to that in General Relativity under a disformal transformation. Our general formula will be useful to constrain inflationary models from the future precise measurement of the B-mode polarization in the cosmic microwave background.
description: 11 pages, no figures
In vitro antimicrobial susceptibility of penicillinase-producing and intrinsically resistant Neisseria gonorrhoeae strains.
Creators: name: Sparling, P F
name: Cooney, M H
name: Cohen, M S
name: Blackman, E
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: The in vitro susceptibility of penicillinase-producing and intrinsically resistant Neisseria gonorrhoeae strains to 13 antimicrobial agents was tested. Regardless of the type of resistance, these organisms remained quite susceptible to newer cephalosporin agents, including moxalactam, cefoperazone, cefotaxime, and ceftazidime.
Pilot Contamination in Massive MIMO Systems: Challenges and Future Prospects
Creators: name: Saeed, Muhammad Kamran
name: Khokhar, Ashfaq
name: Ahmed, Shakil
Publisher: name: arXiv
Year: 2024
Subjects: subject: Information Theory (cs.IT)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Computer Science and Game Theory (cs.GT)
subject: Machine Learning (cs.LG)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Massive multiple input multiple output (M-MIMO) technology plays a pivotal role in fifth-generation (5G) and beyond communication systems, offering a wide range of benefits, from increased spectral efficiency (SE) to enhanced energy efficiency and higher reliability. However, these advantages are contingent upon precise channel state information (CSI) availability at the base station (BS). Ensuring precise CSI is challenging due to the constrained size of the coherence interval and the resulting limitations on pilot sequence length. Therefore, reusing pilot sequences in adjacent cells introduces pilot contamination, hindering SE enhancement. This paper reviews recent advancements and addresses research challenges in mitigating pilot contamination and improving channel estimation, categorizing the existing research into three broader categories: pilot assignment schemes, advanced signal processing methods, and advanced channel estimation techniques. Salient representative pilot mitigation/assignment techniques are analyzed and compared in each category. Lastly, possible future research directions are discussed.
description: Accepted At IWCMC 2024 Comm & SP Symposium
Additional file 1 of Novel application of one-step pooled molecular testing and maximum likelihood approaches to estimate the prevalence of malaria parasitaemia among rapid diagnostic test negative samples in western Kenya
Creators: name: Shah, Monica P.
name: Chebore, Winnie
name: Lyles, Robert H.
name: Otieno, Kephas
name: Zhou, Zhiyong
name: Plucinski, Mateusz
name: Waller, Lance A.
name: Odongo, Wycliffe
name: Lindblade, Kim A.
name: Kariuki, Simon
name: Samuels, Aaron M.
name: Desai, Meghna
name: Mitchell, Rebecca M.
name: Shi, Ya Ping
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Computational Biology

description: Additional file 1. Methods for sample size determination and sampling weights.
Modified algebraic Bethe ansatz for XXZ chain on the segment - II - general cases
Creators: name: Belliard, Samuel
name: Pimenta, Rodrigo A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: The spectral problem of the Heisenberg XXZ spin-$\frac{1}{2}$ chain on the segment is investigated within a modified algebraic Bethe ansatz framework. We consider in this work the most general boundaries allowed by integrability. The eigenvalues and the eigenvectors are obtained. They are characterised by a set of Bethe roots with cardinality equal to $N$, the length of the chain, and which satisfies a set of Bethe equations with an additional term.
description: V2 published version
Phosphorylation of acyclovir in vitro in activated Burkitt somatic cell hybrids.
Creators: name: Pagano, J S
name: Datta, A K
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: Acyclovir [9-(2-hydroxyethoxymethyl)guanine] (ACV), a potent antiviral compound, was phosphorylated to the same extent by extracts from untreated and iododeoxyuridine-treated Epstein-Barr virus-containing latent D98/HR-1 somatic hybrid cells. ATP was the preferred phosphate donor over other nucleoside triphosphates. The cytosol extract from D98/HR-1 cells effected optimum phosphorylation of thymidine at pH 8.0, whereas ACV was phosphorylated equally well over a wide pH range. Electrophoretic analysis of thymidine kinase-, deoxycytidine kinase-, and ACV-phosphorylating activities from both untreated and iododeoxyuridine-treated cell extracts displayed identical properties. A small part (5 to 10%) of the loaded ACV-phosphorylating activity seemed to migrate with the deoxycytidine kinase activity from cytosol. dTTP and dCTP, at relatively high concentrations, partially inhibited ACV-phosphorylating activity. The results suggest that Epstein-Barr virus does not code for its own thymidine kinase and that phosphorylation of ACV in Epstein-Barr virus-producing cells is carried out by multiple or as yet unidentified ATP-dependent nonspecific cellular phosphotransferases.
Mechanical Manipulations on Electronic Transport of Graphene Nanoribbons
Creators: name: Wang, Jing
name: Zhang, Guiping
name: Ye, Fei
name: Wang, Xiaoqun
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the effects of uniaxial strains on the transport properties of the graphene nanoribbons(GNRs) connected with two metallic leads in heterojunctions, using the transfer matrix method. Two typical GNRs with zigzag and armchair boundaries are considered, and the tension is applied either parallel or perpendicular to the ribbon axis. It turns out that the electron-hole symmetry is missing in the gate voltage dependence of the conductance data of the armchair GNRs, while it persists in the zigzag ribbons under any strains. For an armchair GNR with a vertical tension applied, a sharp drop of conductance is found near the critical value of the strain inducing a quantum phase transition, which allows to determine the critical strain accurately via measuring the conductance. In the zigzag ribbon, there exists a range of gate voltage around zero, where the conductance is insensitive to the small horizontal strains. The band structures and low-energy properties are calculated to elucidate the mechanism on the strain effects in GNRs. We expect that our results can be useful in developing graphene-based strain sensors.
description: 11 pages, 11 figures
Gauge Invariance and Holographic Renormalization
Creators: name: Kim, Keun-Young
name: Kim, Kyung Kiu
name: Seo, Yunseok
name: Sin, Sang-Jin
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study the gauge invariance of physical observables in holographic theories under the local diffeomorphism. We find that gauge invariance is intimately related to the holographic renormalisation: the local counter terms defined in the boundary cancel most of gauge dependences of the on-shell action as well as the divergences. There is a mismatch in the degrees of freedom between the bulk theory and the boundary one. We resolve this problem by noticing that there is a residual gauge symmetry(RGS). By extending the RGS such that it satisfies infalling boundary condition at the horizon, we can understand the problem in the context of general holographic embedding of a global symmetry at the boundary into the local gauge symmetry in the bulk.
description: 14 pages, v2: minor changes, typos corrected, references added
Figure S3: Alignment of podosomes along the topographical cues does not depend on microtubules or myosin-II filaments from Forces and constraints controlling podosome assembly and disassembly
Creators: name: Rafiq, Nisha Mohd
name: Grenci, Gianluca
name: Lim, Cheng Kai
name: Kozlov, Michael M.
name: Jones, Gareth E.
name: Viasnoff, Virgile
name: Bershadsky, Alexander D.
Publisher: name: Figshare
Year: 2019
Subjects: subject: Cell Biology
subject: 110601 Biomechanics
subject: FOS: Health sciences

description: See manuscript for legend description of all figures
Susceptibility of phosphonoformic acid-resistant herpes simplex virus variants to arabinosylnucleosides and aphidicolin.
Creators: name: Cheng, Y C
name: Bastow, K F
name: Derse, D D
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: A plaque-reduction assay was used to examine the susceptibility of five phosphonoformic acid-resistant variants of herpes simplex virus type 1 to arabinosylnucleosides and aphidicolin. These viruses were cross-resistant to arabinosylhypoxanthine and to arabinosyladenine when tested in the absence of deoxycoformycin, a deaminase inhibitor. In the presence of deoxycoformycin, no cross-resistance between arabinosyladenine and phosphonoformic acid was observed. The two variants tested were cross-resistant to arabinosylthymine, and all five variants were collaterally susceptible to aphidicolin inhibition.
(De-)Coding Culture. Wie Besucher*innen mit KI Museen neu erleben.
Creators: name: Hass, Rebecca
name: Otte, Josefine
name: Schuhmacher, Timo
Publisher: name: Zenodo
Year: 2022
Subjects: Partizipation
Teilhabe
Besucherforschung
Prototyp
Konzeptentwicklung
Künstliche Intelligenz
KI
Museum
Staatliche Museen zu Berlin

description: Wie können wir den Museumsbesuch digital erweitern? Um diese Frage zu beantworten, müssen wir die Perspektive der Besucher*innen einnehmen. Mit (De-)Coding Culture rücken wir sie in den Mittelpunkt.
 Für die Erweiterung der Sammlungen Online bei den Staatlichen Museen zu Berlin durch Technologien der Künstlichen Intelligenz haben wir deswegen die Besucher*innen selbst zu Wort kommen lassen. In drei Workshops sind wir mit einer Fokusgruppe in den Austausch getreten, haben Fragen gestellt und gemeinsam alle Aspekte rund um den Museumsbesuch diskutiert. Aus den Erkenntnissen haben wir einen Visions-Prototyp für eine KI-basierte Museums-App entwickelt. Hier dokumentieren wir die Workshops, die Gedanken, die ihnen vorangegangen sind, und die App-Idee, die aus ihnen entstanden ist.
description: Diese Publikation ist entstanden im Verbundprojekt museum4punkt0 – Digitale Strategien für das Museum der Zukunft. Weitere Informationen: www.museum4punkt0.de. Das Projekt museum4punkt0 wird gefördert durch die Beauftragte der Bundesregierung für Kultur und Medien aufgrund eines Beschlusses des Deutschen Bundestages. This publication is part of the project museum4punkt0 - Digital Strategies for the Museum of the Future. Further information: www.museum4punkt0.de/en/. The project museum4punkt0 is funded by the Federal Government Commissioner for Culture and the Media in accordance with a resolution issued by the German Bundestag (Parliament of the Federal Republic of Germany).
TESS hunt for young and maturing exoplanets (THYME). V. A sub-neptune transiting a young star in a newly discovered 250myr association
Creators: name: McLean, B.
name: Wood, M.L.
name: Seager, S.
name: Collins, K.A.
name: Osborn, H.
name: Jenkins, J.M.
name: Fűrész, G.
name: Tofflemire, B.M.
name: Ricker, G.R.
name: Twicken, J.D.
name: Howell, S.B.
name: Glidden, A.
name: Boyd, P.T.
name: Rizzuto, A.C.
name: Vanderspek, R.
name: Essack, Z.
name: Schwarz, R.P.
name: Bouma, L.G.
name: Zhou, G.
name: Winn, J.N.
name: Stassun, K.G.
name: Newton, E.R.
name: Vanderburg, A.
name: Wohler, B.
name: Mann, A.W.
name: Nelson, T.
name: Quinn, S.N.
name: Latham, D.W.
name: Kraus, A.L.
name: Hawkins, K.
Publisher: name: American Astronomical Society
Year: 2021

description: The detection and characterization of young planetary systems offer a direct path to study the processes that shape planet evolution. We report on the discovery of a sub-Neptune-sized planet orbiting the young star HD 110082 (TOI-1098). Transit events we initially detected during TESS Cycle 1 are validated with time-series photometry from Spitzer. High-contrast imaging and high-resolution, optical spectra are also obtained to characterize the stellar host and confirm the planetary nature of the transits. The host star is a late-F dwarf (Må = 1.2Me) with a low-mass, M dwarf binary companion (Må = 0.26Me) separated by nearly one arcminute (∼6200 au). Based on its rapid rotation and Lithium absorption, HD 110082 is young, but is not a member of any known group of young stars (despite proximity to the Octans association). To measure the age of the system, we search for coeval, phase-space neighbors and compile a sample of candidate siblings to compare with the empirical sequences of young clusters and to apply quantitative age-dating techniques. In doing so, we find that HD 110082 resides in a new young stellar association we designate MELANGE-1, with an age of 250-+7050 Myr. Jointly modeling the TESS and Spitzer light curves, we measure a planetary orbital period of 10.1827 days and radius of Rp = 3.2 ± 0.1R+. HD 110082 b’s radius falls in the largest 12% of field-age systems with similar host-star mass and orbital period. This finding supports previous studies indicating that young planets have larger radii than their field-age counterparts.
title: A Virtual Reality Front-end for City Modeling
Creators: name: Rando, Eduard
name: Andujar, Carlos
name: Patow, Gustavo A.
Publisher: name: The Eurographics Association
Year: 2019
Subjects: Computing methodologies
Rendering

description: Current tools for city modeling, including those supporting procedural techniques, have a steep learning curve and require substantial user input and/or skills to create realistic 3D models of cities. In this paper we propose a VR tool for the fast and intuitive creation of 3D models of cities through their main elements (buildings, blocks and streets). The key ingredients of our approach are: (a) intuitive creation of mass volume models for buildings, whose facades can be refined later on through procedural rules, (b) the ability to use arbitrary urban layouts, either created from scratch within the tool or imported from public map services, (c) algorithms to replicate and transfer user-generated blocks to arbitrary block shapes, so that a few template blocks suffice to cover the whole urban layout. The major benefit of our approach is that city design and inspection tasks are done simultaneously in a completely immersive environment.
description: Spanish Computer Graphics Conference (CEIG)
description: Short Papers
description: 89
description: 92
description: Eduard Rando, Carlos Andujar, and Gustavo A. Patow
description: CCS Concepts: Computing methodologies--> Rendering
Additional file 1 of Automatic segmentation of the great arteries for computational hemodynamic assessment
Creators: name: Montalt-Tordera, Javier
name: Pajaziti, Endrit
name: Jones, Rod
name: Sauvage, Emilie
name: Puranik, Rajesh
name: Singh, Aakansha Ajay Vir
name: Capelli, Claudio
name: Steeden, Jennifer
name: Schievano, Silvia
name: Muthurangu, Vivek
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1. Supplementary Materials A.
Effect of synthetic protease inhibitors of the amidine type on cell injury by Rickettsia rickettsii.
Creators: name: Geratz, J D
name: Rector, T M
name: Walker, D H
name: Tidwell, R R
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1984

description: To evaluate the importance of proteolytic activity in the pathogenesis of cell injury by Rickettsia rickettsii, a series of four aromatic amidine inhibitors of trypsin-like proteases were introduced into the plaque model. The compounds were shown to be active toward plaque reduction with their order of effectiveness parallel to their antitrypsin activity. One of the compounds, bis(5-amidino-2-benzimidazolyl)-methane, at a concentration of 10(-5) M demonstrated complete inhibition of plaque formation on day 6. Bis(5-amidino-2-benzimidazolyl)methane at the same concentration reduced cell injury even when added to the system after 72 h of rickettsial infection. The reduction in morbidity in guinea pigs experimentally infected with R. rickettsii and treated with bis(5-amidino-2-benzimidazolyl)methane as compared with morbidity in infected, untreated animals, comprised delay in the onset of fever and slightly fewer febrile animals. Because bis(5-amidino-2-benzimidazolyl)methane had no effect on phospholipase A2, the enzyme activity associated with penetration-induced cell injury, it is likely that a trypsin-like protease also plays an essential role either in the physiology of R. rickettsii or as its pathogenic mechanism.
TOI-954 b and K2-329 b: Short-period saturn-mass planets that test whether irradiation leads to inflation
Creators: name: Zhang, H.
name: Teske, J.K.
name: Kane, S.R.
name: Narita, N.
name: Huang, C.X.
name: Rojas, F.
name: Jensen, E.L.N.
name: Mann, A.W.
name: Tamura, M.
name: Stassun, K.G.
name: Vanderburg, A.
name: Hagelberg, J.
name: Ziegler, C.
name: Bouchy, F.
name: Bayliss, D.
name: Zhou, G.
name: Vezie, M.
name: Rodriguez, J.E.
name: Jenkins, J.M.
name: Burt, J.A.
name: Díaz, M.R.
name: Crossfield, I.J.M.
name: Ricker, G.R.
name: Vanderspek, R.K.
name: Latham, D.W.
name: Colón, K.D.
name: Henze, C.E.
name: Tan, T.-G.
name: Penev, K.
name: Udry, S.
name: Mengel, M.W.
name: Nespral, D.
name: Collins, K.A.
name: Sarkis, P.
name: Matthews, E.C.
name: Zapata, A.
name: Nielsen, L.D.
name: Bieryla, A.
name: Livingston, J.H.
name: Wright, D.J.
name: Espinoza, N.
name: Sha, L.
name: Cloutier, R.
name: Brahm, R.
name: Feinstein, A.D.
name: Shporer, A.
name: Hart, R.
name: Montet, B.T.
name: Plavchan, P.
name: Ottoni, G.
name: Hartman, J.D.
name: Winn, J.N.
name: Seager, S.
name: Henning, T.
name: Krishnamurthy, A.
name: Kielkopf, J.F.
name: Schwarz, R.P.
name: Dragomir, D.
name: Ting, E.B.
name: Drass, H.
name: Addison, B.C.
name: Mancini, L.
name: Jordán, A.
name: Crane, J.D.
name: Barbieri, M.
name: Villanueva, S.
name: Torres, P.
name: Wittenmyer, R.A.
name: Okumura, J.
name: Bakos, G.Á.
name: Snoddy, E.
name: Horner, J.
name: Wang, S.
Publisher: name: American Astronomical Society
Year: 2021

description: We report the discovery of two short-period Saturn-mass planets, one transiting the G subgiant TOI-954 (TIC 44792534, V = 10.343, T = 9.78) observed in TESS sectors 4 and 5 and one transiting the G dwarf K2-329 (EPIC 246193072, V = 12.70, K = 10.67) observed in K2 campaigns 12 and 19. We confirm and characterize these two planets with a variety of ground-based archival and follow-up observations, including photometry, reconnaissance spectroscopy, precise radial velocity, and high-resolution imaging. Combining all available data, we find that TOI-954 b has a radius of 0.852+0.053-0.062 RJ and a mass of 0.174+0.018-0.017 MJ and is in a 3.68 day orbit, while K2-329 b has a radius of 0.774+0.026-0.024 RJ and a mass of 0.260+0.020-0.022 MJ and is in a 12.46 day orbit. As TOI-954 b is 30 times more irradiated than K2-329 b but more or less the same size, these two planets provide an opportunity to test whether irradiation leads to inflation of Saturn-mass planets and contribute to future comparative studies that explore Saturn-mass planets at contrasting points in their lifetimes.
Effects of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new antiherpesvirus compound, on synthesis of macromolecules in herpes simplex virus-infected cells.
Creators: name: Bastow, K F
name: Frank, K B
name: Dutschman, G E
name: Grill, S P
name: Nakayama, K
name: Cheng, Y C
name: Chiou, J F
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1984

description: We examined the effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG) on viral DNA, RNA, protein, and enzyme synthesis in HeLa cells infected with herpes simplex virus type 1 and type 2. DHPG inhibited virus DNA synthesis in a dose-dependent fashion. This inhibition was not due to the lack of deoxynucleoside triphosphates which are required for DNA synthesis. This compound has no apparent effect on early and late viral RNA synthesis, viral protein synthesis, or viral thymidine kinase, DNA polymerase, and DNase induction in virus-infected cells.
A quantum approach to homomorphic encryption
Creators: name: Tan, Si-Hui
name: Kettlewell, Joshua A.
name: Ouyang, Yingkai
name: Chen, Lin
name: Fitzsimons, Joseph F.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Cryptography and Security (cs.CR)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Encryption schemes often derive their power from the properties of the underlying algebra on the symbols used. Inspired by group theoretic tools, we use the centralizer of a subgroup of operations to present a private-key quantum homomorphic encryption scheme that enables a broad class of quantum computation on encrypted data. A particular instance of our encoding hides up to a constant fraction of the information encrypted. This fraction can be made arbitrarily close to unity with overhead scaling only polynomially in the message length. This highlights the potential of our protocol to hide a non-trivial amount of information, and is suggestive of a large class of encodings that might yield better security.
description: 5 pages, 1 figure. Improved security bound over previous version. An erroneous proof of universality has been removed
Restrictions on Forcings That Change Cofinalities
Creators: name: Hayut, Yair
name: Karagila, Asaf
Publisher: name: arXiv
Year: 2015
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics
subject: Primary 03E35, Secondary 03E55

description: In this paper we investigate some properties of forcing which can be considered "nice" in the context of singularizing regular cardinals to have an uncountable cofinality. We show that such forcing which changes cofinality of a regular cardinal, cannot be too nice and must cause some "damage" to the structure of cardinals and stationary sets. As a consequence there is no analogue to the Prikry forcing, in terms of "nice" properties, when changing cofinalities to be uncountable.
description: 8 pages; post-refereeing version
The μ Tau association: A 60 Myr old coeval group at 150 pc from the Sun
Creators: name: Mamajek, E.E.
name: Faherty, J.K.
name: Mann, A.W.
name: Gagne, J.
name: Bedard, A.
name: David, T.J.
Publisher: name: IOP Publishing Ltd
Year: 2020

description: We present an analysis of the newly identified μTau Association (MUTA) of young stars at ≈150 pc from the Sun that is part of the large Cas-Tau structure, coeval and comoving with the α Persei cluster. This association is also located in the vicinity of the Taurus-Auriga star-forming region and the Pleiades association, although it is unrelated to them. We identify more than 500 candidate members of MUTA using Gaia DR2 data and the BANYAN Σ tool, and we determine an age of 62 ± 7 Myr for its population based on an empirical comparison of its color-magnitude diagram sequence with those of other nearby young associations. The MUTA association is related to the Theia 160 group of Kounkel & Covey and corresponds to the e Tau group of Liu et al. It is also part of the Cas-Tau group of Blaauw. As part of this analysis, we introduce an iterative method based on spectral templates to perform an accurate correction of interstellar extinction of Gaia DR2 photometry, needed because of its wide photometric bandpasses. We show that the members of MUTA display an expected increased rate of stellar activity and faster rotation rates compared with older stars, and that literature measurements of the lithium equivalent width of nine G0- to K3-type members are consistent with our age determination. We show that the present-day mass function of MUTA is consistent with other known nearby young associations. We identify WD 0340+103 as a hot, massive white dwarf remnant of a B2 member that left its planetary nebula phase only 270,000 yr ago, posing an independent age constraint of - 60+8-6 Myr for MUTA, consistent with our isochrone age. This relatively large collection of comoving young stars near the Sun indicates that more work is required to unveil the full kinematic structure of the complex of young stars surrounding α Persei and Cas-Tau.
Identification of an envelope mutation (env-10) resulting in increased antibiotic susceptibility and pyocin resistance in a clinical isolate of Neisseria gonorrhoeae.
Creators: name: Sparling, P F
name: Lind, I
name: Guymon, L F
name: Shafer, W M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1984

description: A mutation (env-10) conferring increased susceptibility to drugs, dyes, and detergents was detected in a clinical isolate of Neisseria gonorrhoeae. In certain strains, env-10 also affected susceptibility to pyocins. This mutation was phenotypically similar to but genotypically distinct from previously described env mutations.
Additional file 2 of Automatic segmentation of the great arteries for computational hemodynamic assessment
Creators: name: Montalt-Tordera, Javier
name: Pajaziti, Endrit
name: Jones, Rod
name: Sauvage, Emilie
name: Puranik, Rajesh
name: Singh, Aakansha Ajay Vir
name: Capelli, Claudio
name: Steeden, Jennifer
name: Schievano, Silvia
name: Muthurangu, Vivek
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 2. Supplementary Materials B.
Interaction effects on a Majorana zero mode leaking into a quantum dot
Creators: name: Ruiz-Tijerina, David A.
name: Vernek, E.
name: da Silva, Luis G. G. V. Dias
name: Egues, J. C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We have recently shown [Phys. Rev. B {\bf 89}, 165314 (2014)] that a non--interacting quantum dot coupled to a one--dimensional topological superconductor and to normal leads can sustain a Majorana mode even when the dot is expected to be empty, \emph{i.e.}, when the dot energy level is far above the Fermi level of he leads. This is due to the Majorana bound state of the wire leaking into the quantum dot. Here we extend this previous work by investigating the low--temperature quantum transport through an {\it interacting} quantum dot connected to source and drain leads and side--coupled to a topological wire. We explore the signatures of a Majorana zero--mode leaking into the quantum dot for a wide range of dot parameters, using a recursive Green's function approach. We then study the Kondo regime using numerical renormalization group calculations. We observe the interplay between the Majorana mode and the Kondo effect for different dot-wire coupling strengths, gate voltages and Zeeman fields. Our results show that a "0.5" conductance signature appears in the dot despite the interplay between the leaked Majorana mode and the Kondo effect. This robust feature persists for a wide range of dot parameters, even when the Kondo correlations are suppressed by Zeeman fields and/or gate voltages. The Kondo effect, on the other hand, is suppressed by both Zeeman fields and gate voltages. We show that the zero--bias conductance as a function of the magnetic field follows a well--known universality curve. This can be measured experimentally, and we propose that the universal conductance drop followed by a persistent conductance of $0.5\,e^2/h$ is evidence of the presence of Majorana--Kondo physics. These results confirm that this "0.5" Majorana signature in the dot remains even in the presence of the Kondo effect.
description: 19 pages, 12 figures
Lawvere Theories and Definable Operations
Creators: name: LeBlanc, Frédéric
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2022
Subjects: Isotropy
Lawvere theory
Inner theory

description: We introduce the inner theory or, more verbosely, isotropy Lawvere theory functor, which generalizes the isotropy group/monoid by assigning a Lawvere theory of coherently extendable arrows to each object of a category with finite powers. Then, we characterize the inner theory for categories of models of an algebraic (or, more generally, quasi-equational) theory, and note its relationship with a notion of definability for morphisms. Finally, we explore a variety of examples.
Suppression of respiratory syncytial virus infection in cotton rats by bis(5-amidino-2-benzimidazolyl)methane.
Creators: name: Tidwell, R R
name: Rosenthal, K U
name: Clyde, W A
name: Geratz, J D
name: Dubovi, E J
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1984

description: Intraperitoneal administration of bis(5-amidino-2-benzimidazolyl)methane at well-tolerated daily doses of 25 mg/kg subsequent to challenge and for 3 days thereafter effected over a 1-log reduction in the amount of virus recovered from lungs of cotton rats inoculated intratracheally with respiratory syncytial virus. When animals were immunosuppressed to prolong virus shedding, the reduction in recovered virus achieved with a 7-day dosing schedule of bis(5-amidino-2-benzimidazolyl)methane exceeded 2 logs.
Orbital Parameter Determination for Wide Stellar Binary Systems in the Age of Gaia
Creators: name: Newton, E.R.
name: Tofflemire, B.M.
name: Dupuy, T.J.
name: Pearce, L.A.
name: Mann, A.W.
name: Vanderburg, A.
name: Kraus, A.L.
Publisher: name: Institute of Physics Publishing
Year: 2020

description: The orbits of binary stars and planets, particularly eccentricities and inclinations, encode the angular momentum within these systems. Within stellar multiple systems, the magnitude and (mis)alignment of angular momentum vectors among stars, disks, and planets probes the complex dynamical processes guiding their formation and evolution. The accuracy of the Gaia catalog can be exploited to enable comparison of binary orbits with known planet or disk inclinations without costly long-term astrometric campaigns. We show that Gaia astrometry can place meaningful limits on orbital elements in cases with reliable astrometry, and discuss metrics for assessing the reliability of Gaia DR2 solutions for orbit fitting. We demonstrate our method by determining orbital elements for three systems (DS Tuc AB, GK/GI Tau, and Kepler-25/KOI-1803) using Gaia astrometry alone. We show that DS Tuc AB's orbit is nearly aligned with the orbit of DS Tuc Ab, GK/GI Tau's orbit might be misaligned with their respective protoplanetary disks, and the Kepler-25/KOI-1803 orbit is not aligned with either component's transiting planetary system. We also demonstrate cases where Gaia astrometry alone fails to provide useful constraints on orbital elements. To enable broader application of this technique, we introduce the python tool lofti_gaiaDR2 to allow users to easily determine orbital element posteriors.
Additional file 3 of Automatic segmentation of the great arteries for computational hemodynamic assessment
Creators: name: Montalt-Tordera, Javier
name: Pajaziti, Endrit
name: Jones, Rod
name: Sauvage, Emilie
name: Puranik, Rajesh
name: Singh, Aakansha Ajay Vir
name: Capelli, Claudio
name: Steeden, Jennifer
name: Schievano, Silvia
name: Muthurangu, Vivek
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 3. Supplementary Materials C.
Comparative efficacy and selectivity of some nucleoside analogs against Epstein-Barr virus.
Creators: name: Pagano, J S
name: Smith, M C
name: Lin, J C
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1985

description: The effects of (2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine (FIAC), 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyluridine (FMAU), 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouridine (FIAU), (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVdU), and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG or BW B759U) on the replication of Epstein-Barr virus (EBV) in vitro were evaluated and compared with that of acyclovir (ACV). The relative potencies of these drugs, on the basis of anti-EBV activity, were: FIAC = FIAU greater than FMAU greater than DHPG greater than BVdU greater than ACV; on the basis of the therapeutic index they were: BVdU greater than DHPG greater than FIAC greater than ACV greater than FIAU greater than FMAU. Differential inhibition of EBV-associated polypeptides by these drugs was observed.
The Simons Observatory: Combining cross-spectral foreground cleaning with multitracer $B$-mode delensing for improved constraints on inflation
Creators: name: Hertig, Emilie
name: Wolz, Kevin
name: Namikawa, Toshiya
name: Lizancos, Antón Baleato
name: Azzoni, Susanna
name: Abril-Cabezas, Irene
name: Alonso, David
name: Baccigalupi, Carlo
name: Calabrese, Erminia
name: Challinor, Anthony
name: Errard, Josquin
name: Fabbian, Giulio
name: Hervías-Caimapo, Carlos
name: Jost, Baptiste
name: Krachmalnicoff, Nicoletta
name: Lonappan, Anto I.
name: Morshed, Magdy
name: Pagano, Luca
name: Sherwin, Blake
Publisher: name: arXiv
Year: 2024
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The Simons Observatory (SO), due to start full science operations in early 2025, aims to set tight constraints on inflationary physics by inferring the tensor-to-scalar ratio $r$ from measurements of CMB polarization $B$-modes. Its nominal design targets a precision $σ(r=0) \leq 0.003$ without delensing. Achieving this goal and further reducing uncertainties requires the mitigation of other sources of large-scale $B$-modes such as Galactic foregrounds and weak gravitational lensing. We present an analysis pipeline aiming to estimate $r$ by including delensing within a cross-spectral likelihood, and demonstrate it on SO-like simulations. Lensing $B$-modes are synthesised using internal CMB lensing reconstructions as well as Planck-like CIB maps and LSST-like galaxy density maps. This $B$-mode template is then introduced into SO's power-spectrum-based foreground-cleaning algorithm by extending the likelihood function to include all auto- and cross-spectra between the lensing template and the SAT $B$-modes. Within this framework, we demonstrate the equivalence of map-based and cross-spectral delensing and use it to motivate an optimized pixel-weighting scheme for power spectrum estimation. We start by validating our pipeline in the simplistic case of uniform foreground spectral energy distributions (SEDs). In the absence of primordial $B$-modes, $σ(r)$ decreases by 37% as a result of delensing. Tensor modes at the level of $r=0.01$ are successfully detected by our pipeline. Even with more realistic foreground models including spatial variations in the dust and synchrotron spectral properties, we obtain unbiased estimates of $r$ by employing the moment-expansion method. In this case, delensing-related improvements range between 27% and 31%. These results constitute the first realistic assessment of the delensing performance at SO's nominal sensitivity level. (Abridged)
description: Updated version accepted by Physical Review D
Constraints on a seesaw model leading to quasidegenerate neutrinos and signatures at the LHC
Creators: name: Bambhaniya, Gulab
name: Khan, Subrata
name: Konar, Partha
name: Mondal, Tanmoy
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider a variant of TeV scale seesaw models in which three additional heavy right handed neutrinos are added to the standard model to generate the quasi-degenerate light neutrinos. This model is theoretically interesting since it can be fully rebuilt from the experimental data of neutrino oscillations except for an unknown factor in the Dirac Yukawa coupling. We study the constrains on this coupling coming from meta-stability of electro-weak vacuum. Even stronger bound comes from the lepton flavor violating decays on this model, especially in a heavy neutrino mass scenario which is within the collider reach. Bestowed with these constrained parameters, we explore the production and discovery potential coming from these heavy neutrinos at the $14$~TeV run of Large Hadron Collider. Signatures with tri-lepton final state together with backgrounds are considered in a realistic simulation.
description: v2: 21 pages, 5 figures, matches with published version
Wie siehst du das? Besonderheiten in der Wahrnehmung und im Denken bei Kindern im Autismus-Spektrum mit einer kognitiven Beeinträchtigung. Eine Literaturarbeit zum aktuellen Forschungsstand
Creators: name: May, Fiona
Publisher: name: Zenodo
Year: 2023
Subjects: Sonderpädagogik
Masterarbeit
Autismus-Spektrum-Störung
kognitive Beeinträchtigung

description: In den letzten Jahrzehnten kam es zu einem Anstieg des öffentlichen Interesses am Autismus-Spektrum, was sich in der aktuellen Forschung und Literatur widerspiegelt. Die Auswirkung einer komorbiden kognitiven Beeinträchtigung erhält jedoch wenig Beachtung.
Das Ziel dieser Masterarbeit liegt darin, im Rahmen einer systematischen Literaturrecherche eine Antwort auf die Leitfrage «Welche Besonderheiten bestehen in der Wahrnehmung und im Denken bei Kindern im Autismus-Spektrum mit einer kognitiven Beeinträchtigung?» auszuarbeiten. Hierzu werden die drei Themenschwerpunkte «Autismus», «kognitive Beeinträchtigung» sowie «Wahrnehmung und Denken» separiert in den Blick genommen und schrittweise zusammengeführt. Es geht im Wesentlichen darum, den aktuellen Forschungsstand zu evaluieren und auf die Fragestellungen hin zu untersuchen, um einen Einblick in die Wirklichkeit von Kindern im Autismus-Spektrum mit einer kognitiven Beeinträchtigung zu erhalten.
title: A Voxel-based Deep Learning Approach for Point Cloud Semantic Segmentation
Creators: name: Díaz-Medina, Miguel
name: Fuertes-García, José Manuel
name: Ogayar-Anguita, Carlos Javier
name: Lucena, Manuel
Publisher: name: The Eurographics Association
Year: 2019
Subjects: Computing methodologies
Computer Graphics
Machine Learning

description: Semantic segmentation has been a research topic in computer vision for decades. This task has become a crucial challenge nowadays due to emergence of new technologies such as autonomous driving. Nonetheless, most existing segmentation methods are not designed for handling the unstructured and irregular nature of 3D point clouds. We propose a voxel-based technique for point cloud data semantic segmentation of 3D point clouds using 3D convolutional neural networks. It uses local voxelizations for learning spatial patterns, and also corrects the imbalance of the data, something very problematic with 3D datasets.
description: Spanish Computer Graphics Conference (CEIG)
description: Short Papers
description: 73
description: 76
description: Miguel Díaz-Medina, José-Manuel Fuertes-García, Carlos-Javier Ogayar-Anguita, and Manuel Lucena
description: CCS Concepts: Computing methodologies--> Computer Graphics; Machine Learning
Colored HOMFLY polynomials for the pretzel knots and links
Creators: name: Mironov, A.
name: Morozov, A.
name: Sleptsov, A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Geometric Topology (math.GT)
subject: Quantum Algebra (math.QA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: With the help of the evolution method we calculate all HOMFLY polynomials in all symmetric representations [r] for a huge family of (generalized) pretzel links, which are made from g+1 two strand braids, parallel or antiparallel, and depend on g+1 integer numbers. We demonstrate that they possess a pronounced new structure: are decomposed into a sum of a product of g+1 elementary polynomials, which are obtained from the evolution eigenvalues by rotation with the help of rescaled SU_q(N) Racah matrix, for which we provide an explicit expression. The generalized pretzel family contains many mutants, undistinguishable by symmetric HOMFLY polynomials, hence, the extension of our results to non-symmetric representations R is a challenging open problem. To this end, a non-trivial generalization of the suggested formula can be conjectured for entire family with arbitrary g and R.
description: 26 pages + tables of pretzel knots up to 10 crossings