cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Kähler-Einstein metrics on smooth Fano toroidal symmetric varieties of type AIII
Creators: name: Hong, Kyusik
name: Hwang, DongSeon
name: Park, Kyeong-Dong
Publisher: name: arXiv
Year: 2022
Subjects: subject: Algebraic Geometry (math.AG)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: Primary: 14M27, 32Q20, Secondary: 32M12, 32Q26, 53C55

description: The wonderful compactification $X_m$ of a symmetric homogeneous space of type AIII$(2,m)$ for each $m \geq 4$ is Fano, and its blowup $Y_m$ along the unique closed orbit is Fano if $m \geq 5$ and Calabi-Yau if $m = 4$. Using a combinatorial criterion for K-polystability of smooth Fano spherical varieties obtained by Delcroix, we prove that $X_m$ admits a Kähler-Einstein metric for each $m \geq 4$ and $Y_m$ admits a Kähler-Einstein metric if and only if $m = 4, 5$.
description: 20 pages, 6 figures
Transportability of model-based estimands in evidence synthesis
Creators: name: Remiro-Azócar, Antonio
Publisher: name: arXiv
Year: 2022
Subjects: subject: Methodology (stat.ME)
subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: In evidence synthesis, effect modifiers are typically described as variables that induce treatment effect heterogeneity at the individual level, through treatment-covariate interactions in an outcome model parametrized at such level. As such, effect modification is defined with respect to a conditional measure, but marginal effect estimates are required for population-level decisions in health technology assessment. For non-collapsible measures, purely prognostic variables that are not determinants of treatment response at the individual level may modify marginal effects, even where there is individual-level treatment effect homogeneity. With heterogeneity, marginal effects for measures that are not directly collapsible cannot be expressed in terms of marginal covariate moments, and generally depend on the joint distribution of conditional effect measure modifiers and purely prognostic variables. There are implications for recommended practices in evidence synthesis. Unadjusted anchored indirect comparisons can be biased in the absence of individual-level treatment effect heterogeneity, or when marginal covariate moments are balanced across studies. Covariate adjustment may be necessary to account for cross-study imbalances in joint covariate distributions involving purely prognostic variables. In the absence of individual patient data for the target, covariate adjustment approaches are inherently limited in their ability to remove bias for measures that are not directly collapsible. Directly collapsible measures would facilitate the transportability of marginal effects between studies by: (1) reducing dependence on model-based covariate adjustment where there is individual-level treatment effect homogeneity or marginal covariate moments are balanced; and (2) facilitating the selection of baseline covariates for adjustment where there is individual-level treatment effect heterogeneity.
description: 34 pages, 3 figures. Accepted for publication by Statistics in Medicine. Corrigendum: removed Equation 6 from v5 as the expression corresponded to the population-average conditional log odds ratio, not the population-average marginal log odds ratio
Data Mining Analysis of the Parkinson's Disease
Creators: name: Wang, Xiaoyuan
Publisher: name: Georgia State University
Year: 2014

description: Biological research is becoming increasingly database driven and statistical learning can be used to discover patterns in the biological data. In the thesis, the supervised learning approaches are utilized to analyze the Oxford Parkinson?s disease detection data and build models for prediction or classification. We construct predictive models based on training set, evaluate their performance by applying these models to an independent test set, and find the best methods for predicting whether people have Parkinson?s disease. The proposed artificial neural network procedure outperforms with the best and highest prediction accuracy, while the logistic and probit regressions are preferred statistical models which can offer better interpretation with the higher prediction accuracy compared to other proposed data mining approaches.
Safety of Computer Interpretation of Normal Triage Electrocardiograms
Creators: name: Jones, Jonathan
name: Katz, Laurence
name: Lewis, Scott M.
name: Hughes, Katie E.
Publisher: name: Wiley
Year: 2017

description: OBJECTIVES: Frequent interruptions within the emergency department may lead to errors that negatively impact patient care. The immediate review of electrocardiograms (ECGs) obtained from triage patients is one source of interruption. Limiting triage ECGs requiring immediate attending review to those interpreted by the computer as abnormal may be one way to reduce interruption. We hypothesize that triage ECGs interpreted by the computer as "normal ECG" are unlikely to have clinical significance that would affect triage care.
METHODS: All triage ECGs performed at the University of North Carolina were collected between November 14, 2014, and March 3, 2015, according to a standard nursing triage protocol using GE machines running Marquette 12SL software. Triage ECGs with a computer interpretation of "normal ECG" were compared to an attending cardiologist's final interpretation. Triage ECGs for which the cardiologist's interpretation differed from the computer interpretation of normal ECG were presented to two emergency physicians (EPs) blinded to the goals of the study. The physicians were asked to evaluate the ECG for clinical significance. Clinical significance was defined as any change from normal that would alter triage care. Triage ECGs were considered true negatives if either the cardiologist agreed with the normal computer interpretation or if both EPs agreed that the ECG did not show clinical significance.
RESULTS: A total of 855 triage ECGs were collected over 16 weeks. A total of 222 (26%) were interpreted by the computer as normal. The negative predictive value for a triage ECGs interpreted by the computer as "normal" was calculated to be 99% (95% confidence interval = 97% to 99%). Of the ECGs with a computer interpretation of normal ECG, 13 had an interpretation by an attending cardiologist other than normal. Two attending EPs reviewed these triage ECGs. One of the 13 ECGs was found to have clinical significance that would alter triage care by one of the EPs. The stated triage intervention was "bed immediately."
CONCLUSIONS: Our data suggest that triage ECGs identified by the computer as normal are unlikely to have clinical significance that would change triage care. Eliminating physician review of triage ECGs with a computer interpretation of normal may be a safe way to improve patient care by decreasing physician interruptions.
Estimating Long-Term Expected Returns
Creators: name: Ma, Rui
name: Marshall, Ben R
name: Nguyen, Nhut H
name: Visaltanachoti, Nuttawat
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 35
subject: Commerce, management, tourism and services
classificationCode: 3502
subject: Banking, finance and investment
classificationCode: 3501
subject: Accounting, auditing and accountability

description: Estimating long-term expected returns as accurately as possible is of critical importance. Researchers typically base their estimates on yield and growth, valuation, or a combined yield, growth, and valuation (“three-component”) framework. We run a horse race of the abilities of different frameworks and input proxies within each framework to estimate 10- and 20-year out-of-sample returns. The three-component model based on the TRCAPE valuation proxy outperforms estimates based on historical mean benchmark returns, with mean square error improvements exceeding 30%. Using this approach in asset allocation decisions results in an improvement in Sharpe ratios of more than 50%.
Discrepancy Principle and Stable Parameter Estimation in Avian Influenza
Creators: name: DeCamp, Linda
Publisher: name: Georgia State University
Year: 2014

description:      In the case of a linear ill-posed problem with noisy data, a version of an a posteriori parameter selection discrepancy principle (DP) is justified for an arbitrary regularization strategy under very general assumptions on the operator and the stabilizer. Its efficiency is demonstrated for a practically important inverse problem in avian influenza. We refer to our result as an abstract discrepancy principle (ADP), which shows that applicability of the DP largely depends on the level of noise in the data rather than the method used for the construction of a specific regularization procedure.
Trichromia rosaceata
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Trichromia
Trichromia rosaceata

description: Trichromia rosaceata (Watson & Goodger, 1986)
Paranerita rosaceata Watson & Goodger, 1986: 10. Replacement name for Paranerita rosacea Rothschild, 1935.
Paranerita rosacea Rothschild, 1935: 244. Junior primary homonym of Paranerita rosacea Rothschild, 1909.
TYPE LOCALITY. — [Brazil], [Pará].
TYPE SPECIMENS. — Described from 2 male syntypes (BMNH; one of the syntypes labeled TYPE).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 199, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Tensor Hypercontraction Form of the Perturbative Triples Energy in Coupled-Cluster Theory
Creators: name: Jiang, Andy
name: Turney, Justin M.
name: Schaefer, Henry F.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We present the working equations for a reduced-scaling method of evaluating the perturbative triples (T) energy in coupled-cluster theory, through the tensor hypercontraction (THC) of the triples amplitudes ($t_{ijk}^{abc}$). Through our method we can reduce the scaling of the (T) energy from the traditional O($N^{7}$) to a more modest O($N^{5}$). We also discuss implementation details to aid future research, development, and software realization of this method. Additionally, we show that this method yields sub-millihartree (mEh) differences from CCSD(T) when evaluating absolute energies, and sub-0.1 kcal/mol energy differences when evaluating relative energies. Finally, we demonstrate that this method converges to the true CCSD(T) energy through the systematic increasing of the rank or eigenvalue tolerance of the orthogonal projector, as well as exhibiting sub-linear to linear error growth with respect to system size.
title: Digital inclusion and mobile media in remote Sarawak
Creators: name: Horn, Christine
name: Gifford, Sandy
name: Rennie, Ellie
name: Riman, Raine Melissa
name: Wee, Lik Hoo Gregory
Publisher: name: Swinburne University of Technology
Year: 2018

description: This research suggests the single most effective strategy for achieving digital inclusion in Sarawak is to provide remote villages with reliable, affordable, publicly accessible internet infrastructure.
Empirical Likelihood Confidence Intervals for the Population Mean Based on Incomplete Data
Creators: name: Valdovinos Alvarez, Jose
Publisher: name: Georgia State University
Year: 2015

description: The use of doubly robust estimators is a key for estimating the population mean response in the presence of incomplete data. Cao et al. (2009) proposed an alternative doubly robust estimator which exhibits strong performance compared to existing estimation methods. In this thesis, we apply the jackknife empirical likelihood, the jackknife empirical likelihood with nuisance parameters, the profile empirical likelihood, and an empirical likelihood method based on the influence function to make an inference for the population mean. We use these methods to construct confidence intervals for the population mean, and compare the coverage probabilities and interval lengths using both the ``usual'' doubly robust estimator and the alternative estimator proposed by Cao et al. (2009). An extensive simulation study is carried out to compare the different methods. Finally, the proposed methods are applied to two real data sets.
Vertical Status : Evidence from High-Rise Condominiums
Creators: name: Ben-Shahar, Danny
name: Yongheng, Deng
name: Solganik, Eyal
name: Somerville, Tsur
name: Hongjia, Zhu
Publisher: name: The University of British Columbia
Year: 2023

description: The basic model in economics assumes that individual utility is a function of an individual’s own consumption. Yet, the pursuit of status, which depends on the recognition of others and one’s standing relative to others, is an important driver of human behavior. In this paper we estimate the value of a specific aspect of status: relative positioning. Our study is motivated by the literature in linguistics and psychology that correlates between the vertical ordering and well-being. We estimate the price that people are willing to pay for relatively higher position in vertical physical space. Using an extensive dataset of condominium transactions in mid- and high-rise buildings in Vancouver (Canada), we measure the premium paid for an apartment based on its relative height compared to other apartments in the same building and to the heights of nearby buildings. Controlling for unit characteristics, including actual height and view, along with building and time fixed effects, we find that there is an economically meaningful price premium for being higher up relative to others. Ceteris paribus, moving from the bottom to the top floor of a building generates an average premium of 6.4 percent of the average transaction price. A unit that is higher than all surrounding buildings generates an average premium of 3.7 percent relative to a unit that is below all surrounding buildings. Evidence further shows that people weight more heavily the disutility from having others positioned above them than the utility from having others below them and, correspondingly, that the marginal value of vertical status rises convexly within the building. Results are robust to a series of model and sample specifications.
Frobenius-Like Permutations and Their Cycle Structure
Creators: name: Virani, Adil
Publisher: name: Georgia State University
Year: 2015

description: Polynomial functions over finite fields are a major tool in computer science and electrical engineering and have a long history. Some of its aspects, like interpolation and permutation polynomials are described in this thesis. A complete characterization of subfield compatible polynomials (f in E[x] such that f(K) is a subset of L, where K,L are subfields of E) was recently given by J. Hull. In his work, he introduced the Frobenius permutation which played an important role. In this thesis, we fully describe the cycle structure of the Frobenius permutation. We generalize it to a permutation called a monomial permutation and describe its cycle factorization. We also derive some important congruences from number theory as corollaries to our work.
A Survey on Graph Counterfactual Explanations: Definitions, Methods, Evaluation, and Research Challenges
Creators: name: Prado-Romero, Mario Alfonso
name: Prenkaj, Bardh
name: Stilo, Giovanni
name: Giannotti, Fosca
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Graph Neural Networks (GNNs) perform well in community detection and molecule classification. Counterfactual Explanations (CE) provide counter-examples to overcome the transparency limitations of black-box models. Due to the growing attention in graph learning, we focus on the concepts of CE for GNNs. We analysed the SoA to provide a taxonomy, a uniform notation, and the benchmarking datasets and evaluation metrics. We discuss fourteen methods, their evaluation protocols, twenty-two datasets, and nineteen metrics. We integrated the majority of methods into the GRETEL library to conduct an empirical evaluation to understand their strengths and pitfalls. We highlight open challenges and future work.
Multinomial Logistic Regression Analysis Of Varicella Vaccination - 2011 National Immunization Survey (NIS) ? Teen Survey Data
Creators: name: Fredua, Benjamin
Publisher: name: Georgia State University
Year: 2015

description: The varicella-zoster virus (VZV) causes chickenpox or varicella, a disease primarily in children, and Herpes Zoster (HZ) or zoster or shingles, a disease that affects adults. A 2-dose Varicella vaccination is recommended in the United States, the first dose at age 15-18 months and the second dose at 4 to 6 years. In this study, we used multinomial logistic regression to analysis data from the 2011 National Immunization Survey-Teen (NIS-Teen) to identify factors that have a significant impact on the number of doses (0-dose, 1-dose, or 2-dose) a teen will have. We evaluate Varicella vaccination coverage stratified by Census region and assessed factors independently associated with varicella vaccination.
Trichromia brueckneri
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Trichromia
Trichromia brueckneri

description: Trichromia brueckneri (Gaede, 1928)
Hyponerita brueckneri Gaede, 1928b: 31.
TYPE LOCALITY. — Guatemala.
TYPE SPECIMEN. — Holotype female (ZMHB).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 199, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Dietary Sodium Intake and Mortality among US Older Adults: The Third National Health and Nutrition Examination Survey
Creators: name: Zhao, Lixia
Publisher: name: Georgia State University
Year: 2015

description: Strong evidence has linked dietary sodium intake to blood pressure, but the effects of sodium intake on cardiovascular diseases (CVD) outcomes remain elusive, especially for older population. We examined the association between estimated usual sodium intake and CVD and all-cause mortality in a nationally representative sample of 4068 US adults aged 51 and older surveyed in 1988-1994. After a mean follow-up of 12.9 years from 1988 to 2006, 1680 participants died: 734 from CVD; 392 from ischemic heart disease (IHD); and 144 from stroke. In the Cox proportional models adjusted for sociodemographic variables and CVD risk factors, sodium intake was not significantly associated with all-cause, CVD, IHD and stroke mortality. No significant interactions were observed between sodium intake and sex, race/ethnicity, hypertension status, body mass index or physical activity for any of the outcomes studied. However, among Mexican-Americans sodium intake was significantly and linearly associated with CVD mortality.
Apoptosis versus axon pruning: Molecular intersection of two distinct pathways for axon degeneration
Creators: name: Geden, Matthew J
name: Deshmukh, Mohanish
name: Romero, Selena E
Publisher: name: Elsevier
Year: 2018

description: Neurons are capable of degenerating their axons for the physiological clearance and refinement of unnecessary connections via the programmed degenerative pathways of apoptosis and axon pruning. While both pathways mediate axon degeneration they are however distinct. Whereas in apoptosis the entire neuron, both axons and cell body, degenerates, in the context of axon pruning only the targeted axon segments are selectively degenerated. Interestingly, the molecular pathways mediating axon degeneration in these two contexts have significant mechanistic overlap but also retain distinct differences. In this review, we describe the peripheral neuronal cell culture models used to study the molecular pathways of apoptosis and pruning. We outline what is known about the molecular mechanisms of apoptosis and axon pruning and focus on highlighting the similarities and differences of these two pathways.
A Naturally Fluorescent Mgp Transgenic Mouse for Angiogenesis and Glaucoma Longitudinal Studies
Creators: name: Han, Zongchao
name: Borrás, Teresa
name: Mitra, Rajendra N.
name: Periasamy, Ramesh
name: Asokan, Priyadarsini
Publisher: name: Association for Research in Vision and Ophthalmology (ARVO)
Year: 2018

description: Purpose: Our goal was to generate and characterize a new mouse model in which only angiogenesis- and glaucoma-relevant tissues would be naturally fluorescent. The Matrix Gla (MGP) gene is highly expressed in vascular smooth muscle cells (VSMC) and trabecular meshwork (TM). We sought to direct our Mgp-Cre.KI mouse recombinase to VSMC/TM cells to produce their longitudinal fluorescent profiles.
Methods: Homozygous Mgp-Cre.KI mice were crossed with Ai9 homozygous reporter mice harboring a loxP-flanked STOP cassette preventing transcription of a DsRed fluorescent protein (tdTomato). The F1 double-heterozygous (Mgp-tdTomato) was examined by direct fluorescence, whole mount, histology, and fundus photography. Custom-made filters had 554/23 emission and 609/54 exciter nanometer wavelengths. Proof of concept of the model's usefulness was conducted by inducing guided imaging laser burns. Evaluation of a vessel's leakage and proliferation was followed by noninvasive angiography.
Results: The Mgp-tdTomato mouse was viable, fertile, with normal IOP and ERG. Its phenotype exhibited red paws and snout (cartilage expression), which precluded genotyping. A fluorescent red ring was seen at the limbus and confirmed to be TM expression by histology. The entire retinal vasculature was red fluorescent (VSMC) and directly visualized by fundus photography. Laser burns on the Mgp-tdTomato allowed separation of leakiness and neovascularization evaluation parameters.
Conclusions: The availability of a transgenic mouse naturally fluorescent in glaucoma-relevant tissues and retinal vasculature brings the unique opportunity to study a wide spectrum of single and combined glaucomatous conditions in vivo. Moreover, the Mgp-tdTomato mouse provides a new tool to study mechanisms and therapeutics of retinal angiogenesis longitudinally.
Trends in Herpes Zoster Incidence from 1940 to 2008 Using a Cross-sectional Survey
Creators: name: Hales, Craig
Publisher: name: Georgia State University
Year: 2015

description: Previous healthcare-based studies have reported increasing herpes zoster (HZ) incidence over time; however, this could be an artifact of increased healthcare utilization. This study is a cross-sectional analysis of 15,103 respondents in the 2008 wave of the Health and Retirement Study (HRS) to evaluate changes in HZ incidence from 1940 to 2008. Negative binomial regression is used to model the effect of calendar year, age of onset of HZ, gender and race/ethnicity on HZ incidence. A nonparametric method based on B-spline basis expansion is used to model the effect of calendar year to avoid imposing a predetermined functional form and produce flexible and accurate estimates. This study demonstrates increasing HZ incidence from 1940 to 2008 using self-reported HZ. Although the reason for this increase remains unknown, this study supports the assertion that this trend is real and not an artifact of increasing healthcare utilization for HZ over time.
Accurate Approximation Series for Optimal Targeting Regions in a Neural Growth Model with a Low ?branching Probability
Creators: name: Nieto, Bernardo
Publisher: name: Georgia State University
Year: 2015

description: Understanding the complex growth process of dendritic arbors is essential for the medical field and disciplines like Biology and Neurosciences. The establishment of the dendritic patterns has received increasing attention from experimental researchers that seek to determine the cellular mechanisms that play a role in the growth of neural trees. Our goal in this thesis was to prove the recurrence formula for the probability distribution of all possible neural trees, as well as the formulas of the expected number of active branches and their variances. We also derived formulas for the spatial locations of the optimal targeting region for a tree with branching probability. These formulas were necessary for the simplified stochastic computational model that Osan et al have developed in order to examine how changes in branching probability influence the success of targeting neurons located at different distances away from a starting point.
Measurement of electroweak Z(νν¯)γjj production and limits on anomalous quartic gauge couplings in pp collisions at √s = 13 TeV with the ATLAS detector
Creators: name: ATLAS Collaboration
Publisher: name: Springer Berlin Heidelberg
Year: 2023

description: The electroweak production of Z(νν¯)γ in association with two jets is studied in a regime with a photon of high transverse momentum above 150 GeV using proton–proton collisions at a centre-of-mass energy of 13 TeV at the Large Hadron Collider. The analysis uses a data sample with an integrated luminosity of 139 fb−1 collected by the ATLAS detector during the 2015–2018 LHC data-taking period. This process is an important probe of the electroweak symmetry breaking mechanism in the Standard Model and is sensitive to quartic gauge boson couplings via vector-boson scattering. The fiducial Z(νν¯)γjj cross section for electroweak production is measured to be 0.77+0.34 −0.30 fb and is consistent with the Standard Model prediction. Evidence of electroweak Z(νν¯)γjj production is found with an observed significance of 3.2σ for the background-only hypothesis, compared with an expected significance of 3.7σ. The combination of this result with the previously published ATLAS observation of electroweak Z(νν¯)γjj production yields an observed (expected) signal significance of 6.3σ (6.6σ). Limits on anomalous quartic gauge boson couplings are obtained in the framework of effective field theory with dimension-8 operators.
A Minimal Physiologically Based Pharmacokinetic Model with a Nested Endosome Compartment for Novel Engineered Antibodies
Creators: name: Rode, Frederik
name: Cao, Yanguang
name: Yuan, Dongfen
Publisher: name: Springer Nature
Year: 2018

description: We proposed here a minimal physiologically based pharmacokinetic (mPBPK) model for a group of novel engineered antibodies in mice and humans. These antibodies are designed with altered binding properties of their Fc domain with neonatal Fc receptor (FcRn) or the Fab domain with their cognate targets (recycling antibodies) in acidic endosomes. To enable simulations of such binding features in the change of antibody pharmacokinetics and its target suppression, we nested an endothelial endosome compartment in parallel with plasma compartment based on our previously established mPBPK model. The fluid-phase pinocytosis rate from plasma to endothelial endosomes was reflected by the clearance of antibodies in FcRn dysfunctional humans or FcRn-knockout mice. The endosomal recycling rate of FcRn-bound antibodies was calculated based on the reported endosomal transit time. The nonspecific catabolism in endosomes was fitted using pharmacokinetic data of a human wild-type IgG1 adalimumab in humans and B21M in human FcRn (hFcRn) transgenic mice. The developed model adequately predicted the pharmacokinetics of infliximab, motavizumab, and an Fc variant of motavizumab in humans and the pharmacokinetics of bevacizumab, an Fc variant of bevacizumab, and a recycling antibody PH-IgG1 and its non-pH dependent counterpart NPH-IgG1 in hFcRn transgenic mice. Our proposed model provides a platform for evaluation of the pharmacokinetics and disposition behaviors of Fc-engineered antibodies and recycling antibodies.
Finite temperature tensor network algorithm for frustrated two-dimensional quantum materials
Creators: name: Schmoll, Philipp
name: Balz, Christian
name: Lake, Bella
name: Eisert, Jens
name: Kshetrimayum, Augustine
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Aimed at a more realistic classical description of natural quantum systems, we present a two-dimensional tensor network algorithm to study finite temperature properties of frustrated model quantum systems and real quantum materials. For this purpose, we introduce the infinite projected entangled simplex operator ansatz to study thermodynamic properties. To obtain state-of-the-art benchmarking results, we explore the highly challenging spin-1/2 Heisenberg anti-ferromagnet on the Kagome lattice, a system for which we investigate the melting of the magnetization plateaus at finite magnetic field and temperature. Making close connection to actual experimental data of real quantum materials, we go on to studying the finite temperature properties of Ca$_{10}$Cr$_7$O$_{28}$. We compare the magnetization curve of this material in the presence of an external magnetic field at finite temperature with classically simulated data. As a first theoretical tool that incorporates both thermal fluctuations as well as quantum correlations in the study of this material, our work contributes to settling the existing controversy between the experimental data and previous theoretical works on the magnetization process.
description: 9 pages, 11 figures
A minimal physiologically based pharmacokinetic model to investigate FcRn-mediated monoclonal antibody salvage: Effects of Kon, Koff, endosome trafficking, and animal species
Creators: name: Maas, Brian M.
name: Cao, Yanguang
Publisher: name: Taylor & Francis
Year: 2018

description: Manipulation of binding affinity between monoclonal antibodies (mAbs) and the neonatal Fc receptor (FcRn) has been leveraged to extend mAb half-life; however, the steps required for success remain ambiguous and experimental observations are inconsistent. Recent models have considered the time course of endosomal transit a major contributor to the relationship between FcRn affinity and antibody half-life. Our objective was to develop a minimal physiologically based pharmacokinetic model to explain how changes in IgG-FcRn association rate constant (Kon), dissociation rate constant (Koff), and endosomal transit time [T(w)] translate to improved IgG clearance across mice, monkeys and humans. By simulating mAb clearance across physiological values of Kon, Koff, and T(w), we found that lowering Koff improves clearance only until the dissociation half-life reaches endosomal transit time. In contrast, Kon influenced clearance independently of T(w). The model was then applied to fit 66 mAb plasma profiles across species digitized from the literature, and clearance of mAb (CLIgG) and vascular fluid-phase endocytosis rate (CLup) were estimated. We found that CLIgG scaled well with body weight (allometric exponent of 0.90). After accounting for mAbs with significant FcRn binding at physiological pH, CLup was allometrically scalable (exponent 0.72). For the antibodies surveyed, Kon was more highly correlated with CLIgG across all species. The relationship between Koff and KD with CLIgG was largely inconsistent. Taken together, this model provides a parsimonious approach to evaluate endosomal transit kinetics using only mAb plasma concentrations. These findings reinforce the idea that endosomal transit kinetics should be considered when modeling FcRn salvage.
Trichromia furva
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Trichromia
Trichromia furva

description: Trichromia furva (Schaus, 1905)
Hyponerita furva Schaus, 1905: 228.
TYPE LOCALITY. — Suriname, Geldersland, Suriname River.
TYPE SPECIMEN. — Holotype male no. 8631 (USNM).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 199, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Optimal exercise of American options under time-dependent Ornstein-Uhlenbeck processes
Creators: name: Azze, Abel
name: D'Auria, Bernardo
name: García-Portugués, Eduardo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Probability (math.PR)
subject: Mathematical Finance (q-fin.MF)
subject: Pricing of Securities (q-fin.PR)
subject: FOS: Mathematics
subject: FOS: Economics and business
subject: 60G40, 60J60

description: We study the barrier that gives the optimal time to exercise an American option written on a time-dependent Ornstein--Uhlenbeck process, a diffusion often adopted by practitioners to model commodity prices and interest rates. By framing the optimal exercise of the American option as a problem of optimal stopping and relying on probabilistic arguments, we provide a non-linear Volterra-type integral equation characterizing the exercise boundary, develop a novel comparison argument to derive upper and lower bounds for such a boundary, and prove its Lipschitz continuity in any closed interval that excludes the expiration date and, thus, its differentiability almost everywhere. We implement a Picard iteration algorithm to solve the Volterra integral equation and show illustrative examples that shed light on the boundary's dependence on the process's drift and volatility.
description: 25 pages, 3 figures
Numerical Solutions to Two-Dimensional Integration Problems
Creators: name: Carstairs, Alexander
Publisher: name: Georgia State University
Year: 2015

description: This paper presents numerical solutions to integration problems with bivariate integrands. Using equally spaced nodes in Adaptive Simpson's Rule as a base case, two ways of sampling the domain over which the integration will take place are examined. Drawing from Ouellette and Fiume, Voronoi sampling is used along both axes of integration and the corresponding points are used as nodes in an unequally spaced degree two Newton-Cotes method. Then the domain of integration is triangulated and used in the Triangular Prism Rules discussed by Limaye. Finally, both of these techniques are tested by running simulations over heavily oscillatory and monomial (up to degree five) functions over polygonal regions.
From equivariant volumes to equivariant periods
Creators: name: Cassia, Luca
name: Piazzalunga, Nicolo
name: Zabzine, Maxim
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Algebraic Geometry (math.AG)
subject: Symplectic Geometry (math.SG)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We consider generalizations of equivariant volumes of abelian GIT quotients obtained as partition functions of 1d, 2d, and 3d supersymmetric GLSM on $S^1$, $D^2$ and $D^2 \times S^1$, respectively. We define these objects and study their dependence on equivariant parameters for non-compact toric Kähler quotients. We generalize the finite-difference equations (shift equations) obeyed by equivariant volumes to these partition functions. The partition functions are annihilated by differential/difference operators that represent equivariant quantum cohomology/K-theory relations of the target and the appearance of compact divisors in these relations plays a crucial role in the analysis of the non-equivariant limit. We show that the expansion in equivariant parameters contains information about genus-zero Gromov-Witten invariants of the target.
description: v2: typos fixed and references added, version to appear in Adv.Theor.Math.Phys
Сфираль времени: структура перехода, резонанс смыслов и сверхпричинность в онтологии русского космизма
Creators: name: Басаргин, Олег Сергеевич
Publisher: name: Zenodo
Year: 2025

description: Сфилрал времени: структура перехода, резонанс смысла и сверхпричинность в онтологии русского космизма

© О.С. Басаргин – исследователь и изобретатель. Председатель Фонда изучения природы времени.

Аннотация

В статье исследуется временная природа как активная структура, обладающая ритмической и резонансной топологией, на примере устройства Сфираль. Вводятся понятия витка, петли, антипетли и узла как элементов временного кода. Время представлено не как параметр измерения, а как субъект перехода, памяти и смысловой связности. Сопоставление проводится с теориями И.Э. Булыженкова и онтологией русского космизма, в которых время — внутренняя сторона материи и связующего поля. Предлагается новый взгляд на архитектуру человеческого бытия, в которой возможна не только линейная причинность, но и обратимость фаз, диалог с Временем и этика включённости.

Абстрактный

В данной работе исследуется природа времени как активной структуры с резонансной и ритмической топологией, используя устройство Сфирала в качестве концептуальной модели. Такие понятия, как катушка, петля, противофаза и узел, вводятся как элементы временного кода. Время интерпретируется не как измеряемый параметр, а как предмет перехода, памяти и семантической когерентности. Проводится сравнение с теориями И.Е. Булыженкова и онтологией русского космизма, где время является внутренним аспектом материи и связующего поля. В статье предлагается новая архитектура человеческого бытия, в которой становятся возможными не только линейная причинность, но и фазовая обратимость, временной диалог, этика включения.

Ключевые слова:

Сфираль; время; русская онтология; поперечный вектор времени; смысловая резонансность; фазовая обратимость; Булыженков; космизм; субъект времени; топология перехода

 

Ключевые слова:

Сфираль; Время; Русская онтология; поперечный вектор времени; семантический резонанс; обратимость фаз; Булыженков; Космизм; время как субъект; Топология перехода
Jackknife Empirical Likelihood for the Concordance Correlation Coefficient
Creators: name: Moss, Anna
Publisher: name: Georgia State University
Year: 2016

description: The concordance correlation coefficient (CCC) is a common measure of reproducibility or agreement between data values in paired samples. Confidence intervals and hypothesis tests of the CCC using normal approximations (NA) have been shown to have poor coverage for highly skewed distributions. This study applies the jackknife empirical likelihood (JEL) to confidence intervals for the CCC and compares coverage probability and interval length for JEL and NA methods. Data are simulated for CCC values between 0.25 - 0.95 from normal and non-normal distributions of varying skewness. Simulation results showed that JEL methods perform better than the NA methods particularly with data from skewed distributions.The JEL methods have the widest confidence intervals in most cases. Application of JEL methods are illustrated by evaluating concordance between self-reported and clinically measured body weight and height from the National Health and Nutrition Examination Survey (NHANES).
Spatial Analysis of Retinal Pigment Epithelium Morphology
Creators: name: Huang, Haitao
Publisher: name: Georgia State University
Year: 2016

description: In patients with age-related macular degeneration, a monolayer of cells in the eyes called retinal pigment epithelium differ from healthy ones in morphology. It is therefore important to quantify the morphological changes, which will help us better understand the physiology, disease progression and classification. Classification of the RPE morphometry has been accomplished with whole tissue data. In this work, we focused on the spatial aspect of RPE morphometric analysis. We used the second-order spatial analysis to reveal the distinct patterns of cell clustering between normal and diseased eyes for both simulated and experimental human RPE data. We classified the mouse genotype and age by the k-Nearest Neighbors algorithm. Radially aligned regions showed different classification power for several cell shape variables. Our proposed methods provide a useful addition to classification and prognosis of eye disease noninvasively.
Gerüche in der Innenraumluft - eine internetbasierte Umfrage zur Belästigung und zu gesundheitlichen Beschwerden
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016

description: In geschlossenen Räumen, sei es am Arbeitsplatz oder in der eigenen Wohnung, ist man gewollt oder ungewollt Gerüchen ausgesetzt. Um mehr über Gerüche, ihre Quellen, Wirkungen und Empfindungen herauszufinden, führte das Umweltbundesamt in Deutschland eine mehrmonatige Internetumfrage durch. Etwa drei Viertel der knapp 300 teilnehmenden Personen fühlte sich von Gerüchen betroffen und beurteilte diese mit überwiegender Mehrheit als "sehr unangenehm" oder "unangenehm" bzw. "belästigend". Etwas vorsichtiger fiel die Einschätzung dieser Gerüche als "nicht akzeptabel" oder "unzumutbar" aus. Im rechtlichen Sinne stellen unzumutbare Gerüche eine erhebliche Belästigung dar, die als Schaden qualifiziert wird. Die wesentlichen gesundheitlichen Beschwerden waren Reizungen der Nase, des Rachens und des Halses; Augenreizungen sowie vor allem bei andauernder Geruchsbelästigung Kopfschmerzen, Benommenheit und Müdigkeit. Als wichtigste Geruchsquellen wurden Bauprodukte, wie Bodenbeläge, Möbel und Wandfarben und Wände genannt. Da Raumnutzer meist nur wenig Einfluss auf Gerüche aus Bauprodukten haben, stellt die Vermeidung von Geruchsemissionen eine anzustrebende Maßnahme dar. Die Einführung einer sensorischen Prüfung in das Beurteilungsschema des Ausschusses zur gesundheitlichen Bewertung von Bauprodukten ist daher sehr zu begrüßen. Quelle: http://www.gefahrstoffe.de
description: In enclosed spaces at work or at home, we are intentionally or unintentionally exposed to odors. The German Environment Agency led a several months̷ survey to learn more about sources, effects and sensations of odors. About three quarters of almost 300 respondents felt affected by odors, and a large majority rated them as ̮very unpleasant̮ or ̮unpleasant̮ or ̮annoying̮. However, the item of ̮acceptanceŁ was assessed more cautiously. In legal terms, unacceptable odors represent a significant annoyance, which is regarded as damage. The main health complaints were irritation of the nose, throat and neck; eye irritation and Ń mainly for persistent odors Ń dizziness, headache and fatigue. Survey participants named building products, such as flooring, furniture and wall colors and walls, as most important sources of odors. Since room occupants usually have little effect on odors from construction products, the avoidance of odor emissions is a desirable measure. Introduction of a sensory test in the assessment scheme of the Committee for the Health-related Evaluation of Building Products is therefore very desirable. Quelle: http://www.gefahrstoffe.de
Dialogue with State Security Actors in Hybrid Regimes: Recommendations for Constructive Engagement
Creators: name: Institute for Integrated Transitions
Publisher: name: Zenodo
Year: 2025
Subjects: IFIT
hybrid regimes
civic society
security
state security
democratic transition
political change
authoritarianism
dialogue
negotiations
coup
security forces
Burkina Faso
Egypt
Georgia
Mali
Mexico
Myanmar
Pakistan
Peru
Sudan
Thailand
partial agreements

description: This IFIT publication is authored by Alejandro Urrutia and Teddy Baker.

Constructive dialogue between civic and state security actors in hybrid regimes is critical for creating pathways to democratic reform and transition. Yet, in most hybrid regime contexts, civic actors interested in peaceful political change avoid engaging state security actors. 

This report highlights the opportunities - and risks - of engagement instead of avoidance. It is the culmination of extensive multi-year research, including 35 in-depth interviews across 10 country case studies: Burkina Faso, Egypt, Georgia, Mali, Mexico, Myanmar, Pakistan, Peru, Sudan, and Thailand. The process engaged hundreds of academics, researchers, practitioners, and civic and state security actors, in dozens of countries around the world. 

“Engaging with state security actors in hybrid regimes is both necessary and challenging,” said Alejandro Urrutia, IFIT Associate and project lead. “These actors often hold the key to either democratic transitions or prolonged authoritarianism. Our research highlights practical strategies that civic actors can use to navigate these complex dynamics.”

Recommendations focus on the importance of building trust through personal relationships, using neutral intermediaries, and developing realistic, incremental goals for engagement. One of the central findings is on the importance of dialogue readiness. “Too often, civic actors find themselves unprepared when a window for engagement opens,” noted Urrutia. “Mapping key security stakeholders, identifying potential allies within the system, and fostering communication channels in advance can make all the difference.”

Report co-author Teddy Baker noted the significance of the research for practitioners and civil society leaders: "We believe the publication can be a vital resource for anyone working at the intersection of security and democratic transition. It provides not only analysis but actionable recommendations for those seeking to foster more inclusive and sustainable political change."
Trichromia ockendeni
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Trichromia
Trichromia ockendeni

description: Trichromia ockendeni (Rothschild, 1909)
Hyponerita ockendeni Rothschild, 1909b: 298.
Hyponerita posterior Rothschild, 1909b:298. — Type locality: Venezuela, [Bolivar], Caura River, La Union. — Type specimen: Holotype female (BMNH).
TYPE LOCALITY. — Peru, [Puno], La Oroya, [Rio] Inambari.
TYPE SPECIMENS. — Described from 4 male syntypes (BMNH; one of the male labeled TYPE).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 199, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Low-dimensional gap plasmons for enhanced light-graphene interactions
Creators: name: Kim, Yunjung
name: Yu, Sunkyu
name: Park, Namkyoo
Publisher: name: arXiv
Year: 2016
Subjects: subject: Optics (physics.optics)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Graphene plasmonics has become a highlighted research area due to the outstanding properties of deep-subwavelength plasmon excitation, long relaxation time, and electro-optical tunability. Although the giant conductivity of a graphene layer enables the low-dimensional confinement of light, the atomic scale of the layer thickness is severely mismatched with optical mode sizes, which impedes the efficient tuning of graphene plasmon modes from the degraded light-graphene overlap. Inspired by gap plasmon modes in noble metals, here we propose low-dimensional graphene gap plasmon waves for large light-graphene overlap factor. We show that gap plasmon waves exhibit superior in-plane and out-of-plane field concentrations on graphene compared to those of edge or wire-like graphene plasmons. By adjusting the chemical property of the graphene layer, efficient and linear modulation of graphene gap plasmon modes is also achieved. Our results provide potential opportunities to low-dimensional graphene plasmonic devices with strong tunability.