cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Paracrine signalling during ZEB1-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in lung fibrosis
Creators: name: Liudi Yao
name: Conforti, Franco
name: Hill, Charlotte
name: Bell, Joseph
name: Drawater, Leena
name: Juanjuan Li
name: Liu, Dian
name: Xiong, Hua
name: Alzetani, Aiman
name: Chee, Serena J
name: Marshall, Ben G
name: Fletcher, Sophie V
name: Hancock, David
name: Coldwell, Mark
name: Xianglin Yuan
name: Ottensmeier, Christian H
name: Downward, Julian
name: Collins, Jane E
name: Ewing, Rob M
name: Richeldi, Luca
name: Skipp, Paul
name: Jones, Mark G
name: Davies, Donna E
name: Yihua Wang
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: Model organisms
Tumour Biology
Signalling & Oncogenes
Gene Expression
Genetics & Genomics
Chemical Biology & High Throughput

description: The contribution of epithelial-mesenchymal transition (EMT) to human lung fibrogenesis is controversial. Here we provide evidence that ZEB1-mediated EMT in human alveolar epithelial type II (ATII) cells contributes to the development of lung fibrosis by paracrine signalling to underlying fibroblasts. Activation of EGFR-RAS-ERK signalling in ATII cells induced EMT via ZEB1. ATII cells had extremely low extracellular matrix gene expression even after induction of EMT, however conditioned media from ATII cells undergoing RAS-induced EMT augmented TGFβ-induced profibrogenic responses in lung fibroblasts. This epithelial-mesenchymal crosstalk was controlled by ZEB1 via the expression of tissue plasminogen activator (tPA). In human fibrotic lung tissue, nuclear ZEB1 expression was detected in alveolar epithelium adjacent to sites of extracellular matrix (ECM) deposition, suggesting that ZEB1-mediated paracrine signalling has the potential to contribute to early fibrotic changes in the lung interstitium. Targeting this novel ZEB1 regulatory axis may be a viable strategy for the treatment of pulmonary fibrosis.
Risk Factors Associated with SARS-CoV-2 Infection among Healthcare Workers in a NonCOVID Hospital in Malaysia
Creators: name: King, Teck Long
name: Foo, Diana Hui-Ping
name: Lee, Huey Chun
name: Priyadarvena Santhramogan
name: Tan, Min Gui
name: Sofina Azurin Bt Soffian Chen
name: Siang Poon Goh
name: Fong, Alan Yean Yip
name: Ngian, Hie Ung
Publisher: name: Zenodo
Year: 2020
Subjects: Risk Factors
SARS-CoV-2
COVID-19
Coronavirus
Healthcare Workers
Malaysia
NonCOVID

description: Introduction Introduction This study aimed to evaluate risk factors associated with SARS-CoV-2 infection among HCWs who had exposure from infected patients and HCWs in a recent outbreak in Sarawak General Hospital (SGH). Materials and Methods We included HCWs who were investigated during contact tracing of SARS-CoV-2 confirmed patients and HCWs in SGH. We analysed the risk factors including personal protective equipment (PPE) use, social distancing, contact duration, hand hygiene practice, and involvement in aerosol producing activities associated with HCW’s SARSCoV-2 infection risk, which was confirmed by using real-time polymerase chain reaction assay. Results We included 2104 HCWs: 62.2% were female with median age of 32 years old. Majority were nurses (45.3%) and doctors (29.8%). Fifty (2.4%) HCWs were later confirmed with SARS-CoV-2 infection. Among them, 12 had exposure from infected patient(s); 34 from infected HCW(s); and four had contacted both infected patient(s) and HCW(s). Discussion & Conclusion Aerosol-producing activities and hand hygiene were the significant risk factors associated with SARSCoV-2 infection risk in HCWs. The findings indicate indirect contact of contaminated surfaces or formite transmission as the possible transmission mode of SARS-CoV-2. Actions are needed to reinforce hand hygiene habits and practice while use of mask and PPEs should not be undermined in the effort of preventing nosocomial transmission of SARS-CoV-2. In univariable and multivariable analyses, in patient-HCW exposure, aerosol-producing activities was the only risk factor significantly associated with SARS-CoV-2 infection [OR=4.55, 95%CI=1.14-18.12], while in HCW-HCW exposure, hand hygiene was the sole significant risk factor (OR=2.21, 95%CI=1.13-4.31). Not wearing mask in HCW-HCW contact showed marginal significance level in univariable analysis (p=0.06, OR=6.98, 95%CI=0.93-50.03). Other risk factors were not found to significantly associated with SARS-CoV-2 infection risk in HCWs
GABA and glutamate neurons in the VTA regulate sleep and wakefulness
Creators: name: Yu, Xiao
name: Li, Wen
name: Ma, Ying
name: Tossell, Kyoko
name: Harris, Julia J
name: Harding, Edward C
name: Ba, Wei
name: Miracca, Giulia
name: Wang, Dan
name: Li, Long
name: Guo, Juan
name: Chen, Ming
name: Yuqi Li
name: Yustos, Raquel
name: Vyssotski, Alexei L
name: Burdakov, Denis
name: Qianzi Yang
name: Hailong Dong
name: Franks, Nicholas P
name: Wisden, William
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Imaging
subject: Microfabrication & Bioengineering
subject: Ecology,Evolution & Ethology
subject: Metabolism
subject: Computational & Systems Biology

description: We screened for novel circuits in the mouse brain that promote wakefulness. Chemogenetic activation experiments and electroencephalogram recordings pointed to glutamatergic/nitrergic (NOS1) and GABAergic neurons in the ventral tegmental area (VTA). Activating glutamatergic/NOS1 neurons, which were wake- and rapid eye movement (REM) sleep-active, produced wakefulness through projections to the nucleus accumbens and the lateral hypothalamus. Lesioning the glutamate cells impaired the consolidation of wakefulness. By contrast, activation of GABAergic VTA neurons elicited long-lasting non-rapid-eye-movement-like sleep resembling sedation. Lesioning these neurons produced an increase in wakefulness that persisted for at least 4 months. Surprisingly, these VTA GABAergic neurons were wake- and REM sleep-active. We suggest that GABAergic VTA neurons may limit wakefulness by inhibiting the arousal-promoting VTA glutamatergic and/or dopaminergic neurons and through projections to the lateral hypothalamus. Thus, in addition to its contribution to goal- and reward-directed behaviors, the VTA has a role in regulating sleep and wakefulness.
Chronology Protection in Two-Dimensional Dilaton Gravity
Creators: name: Mishima, Takashi
name: Nakamichi, Akika
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The global structure of 1 + 1 dimensional compact Universe is studied in two-dimensional model of dilaton gravity. First we give a classical solution corresponding to the spacetime in which a closed time-like curve appears, and show the instability of this spacetime due to the existence of matters. We also observe quantum version of such a spacetime having closed timelike curves never reappear unless the parameters are fine-tuned.
description: 10 pages, plain Tex, phyzzx, TIT/HEP-218/COSMO-29
MASTER optical detection of the first LIGO/Virgo neutron stars merging GW170817
Creators: name: Lipunov, V. M.
name: Gorbovskoy, E.
name: Kornilov, V. G.
name: Tyurina, N .
name: Balanutsa, P.
name: Kuznetsov, A.
name: Vlasenko, D.
name: Kuvshinov, D.
name: Gorbunov, I.
name: Buckley, D. A. H.
name: Krylov, A. V.
name: Podesta, R.
name: Lopez, C.
name: Podesta, F.
name: Levato, H.
name: Saffe, C.
name: Mallamachi, C.
name: Potter, S.
name: Budnev, N. M.
name: Gress, O.
name: Ishmuhametova, Yu.
name: Vladimirov, V.
name: Zimnukhov, D.
name: Yurkov, V.
name: Sergienko, Yu.
name: Gabovich, A.
name: Rebolo, R.
name: Serra-Ricart, M.
name: Israelyan, G.
name: Chazov, V.
name: Wang, Xiaofeng
name: Tlatov, A.
name: Panchenko, M. I.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Following the reported discovery of the gravitational-wave pulse GW170817/ G298048 by three LIGO/Virgo antennae (Abbott et al., 2017a), the MASTER Global Robotic Net telescopes obtained the first image of the NGC 4993 galaxy after the NS+NS merging. The optical transient MASTER OTJ130948.10-232253.3/SSS17a was later found, which appears to be a kilonova resulting from a merger of two neutron stars. In this paper we report the independent detection and photometry of the kilonova made in white light and in B, V, and R filters. We note that luminosity of the discovered kilonova NGC 4993 is very close to another possible kilonova proposed early GRB 130603 and GRB 080503.
description: 17 pages, 5 pages, 3 tables,accepted to ApJL, LVC release on 2017-10-16
title: ADCO, Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Cart. 29 (G 134), 996 folios, f. 0548
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0548, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0548, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Superfluid shells for trapped fermions with mass and population imbalance
Creators: name: Lin, G. -D.
name: Yi, W.
name: Duan, L. -M.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We map out the phase diagram of strongly interacting fermions in a potential trap with mass and population imbalance between the two spin components. As a unique feature distinctively different from the equal-mass case, we show that the superfluid here forms a shell structure which is not simply connected in space. Different types of normal states occupy the trap regions inside and outside this superfluid shell. We calculate the atomic density profiles, which provide an experimental signature for the superfluid shell structure.
description: 4 pages, 3 figures
Wide sigma Orionis binaries resolved by UKIDSS
Creators: name: Caballero, J. A.
name: Novalbos, I.
name: Tobal, T.
name: Miret, F. X.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: In spite of its importance for the study of star formation at all mass domains, the nearby young sigma Orionis cluster still lacks a comprehensive survey for multiplicity. We try to fill that observational gap by looking for wide resolved binaries with angular separations between 0.4 and 4.0 arcsec. We search for companions to 331 catalogued cluster stellar members and candidates in public K-band UKIDSS images outside the innermost 1 arcmin, which is affected by the glare of the bright, eponymous sigma Ori multiple system, and investigate their cluster membership with colour-magnitude diagrams and previous knowledge of youth features. Of the 18 identified pairs, ten have very low individual probabilities of chance alignment (< 1 %) and are considered here as physical pairs. Four of them are new, while the other six had been discovered previously, but never investigated homogeneously and in detail. Projected physical separations and magnitude differences of the ten probably bound pairs range from 180 to 1220 au, and from 0.0 to 3.4 mag in K, respectively. Besides, we identify two cluster stars with elongated point spread functions. We determine the minimum frequency of wide multiplicity in the interval of projected physical separations s = 160-1600 au in sigma Orionis at 3.0^{+1.2}_{-1.1} %. We discover a new Lindroos system, find that massive and X-ray stars tend to be in pairs or trios, conclude that multiplicity truncates circumstellar discs and enhances X-ray emission, and ascribe a reported lithium depletion in a young star to unresolved binarity in spectra of moderate resolution. When accounting for all know multiples, including spectroscopic binaries, the minimum frequency of multiplicity increases to about 10 %, which implies that of the order of 80-100 unknown multiple systems still await discovery in sigma Orionis.
description: Astronomische Nachrichten, accepted
A Twistor Formulation of the Non-Heterotic Superstring with Manifest Worldsheet Supersymmetry
Creators: name: Galperin, A.
name: Sokatchev, E.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We propose a new formulation of the $D=3$ type II superstring which is manifestly invariant under both target-space $N=2$ supersymmetry and worldsheet $N=(1,1)$ super reparametrizations. This gives rise to a set of twistor (commuting spinor) variables, which provide a solution to the two Virasoro constraints. The worldsheet supergravity fields are shown to play the rôle of auxiliary fields.
description: 21p., LaTeX
Additional file 4 of Personalising treatment plan quality review with knowledge-based planning in the TROG 15.03 trial for stereotactic ablative body radiotherapy in primary kidney cancer
Creators: name: Hardcastle, Nicholas
name: Cook, Olivia
name: Ray, Xenia
name: Moore, Alisha
name: Moore, Kevin L.
name: Pryor, David
name: Rossi, Alana
name: Foroudi, Farshad
name: Kron, Tomas
name: Siva, Shankar
Publisher: name: figshare
Year: 2021
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 4. Radiotherapy Pre-treatment case report: Case #51.
The physical origin of the Fresnel drag of light by a moving dielectric medium
Creators: name: Drezet, A.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Optics (physics.optics)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: We present a new derivation of the Fresnel-Fizeau formula for the drag of light by a moving medium using a simple perturbation approach. We focus particulary on the physical origin of the phenomenon and we show that it is very similar to the Doppler-Fizeau effect. We prove that this effect is, in its essential part, independent of the theory of relativity. The possibility of applications in other domains of physics is considered.
description: accepted for publication in EPJB (the European Journal of Physics B)
Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers
Creators: name: S Trebeschi
name: SG Drago
name: NJ Birkbak
name: I Kurilova
name: AM Cǎlin
name: A Delli Pizzi
name: F Lalezari
name: DMJ Lambregts
name: MW Rohaan
name: C Parmar
name: EA Rozeman
name: KJ Hartemink
name: C Swanton
name: JBAG Haanen
name: CU Blank
name: EF Smit
name: RGH Beets-Tan
name: HJWL Aerts
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: Tumour Biology
Signalling & Oncogenes
Genetics & Genomics
Genome Integrity & Repair
Human Biology & Physiology
Chemical Biology & High Throughput
Ecology,Evolution & Ethology
Computational & Systems Biology

description: INTRODUCTION: Immunotherapy is regarded one of the major breakthroughs in cancer treatment. Despite its success, only a subset of patients responds - urging the quest for predictive biomarkers. We hypothesize that Artificial Intelligence (AI) algorithms can automatically quantify radiographic characteristics that are related to and may therefore act as non-invasive radiomic biomarkers for immunotherapy response. PATIENTS AND METHODS: In this study, we analyzed 1055 primary and metastatic lesions from 203 patients with advanced melanoma and non-small cell lung cancer (NSCLC) undergoing anti-PD1 therapy. We performed a AI-based characterization of each lesion on the pretreatment contrast-enhanced CT imaging data to develop and validate a non-invasive machine learning biomarker capable of distinguishing between immunotherapy responding and non-responding. To define the biological basis of the radiographic biomarker, we performed gene-set enrichment analysis in an independent dataset of 262 NSCLC patients. RESULTS: The biomarker reached significant performance on NSCLC lesions (up to 0.83 AUC, p
Composite quasianalytic functions
Creators: name: da Silva, André Belotto
name: Bierstone, Edward
name: Chow, Michael
Publisher: name: arXiv
Year: 2017
Subjects: subject: Complex Variables (math.CV)
subject: Classical Analysis and ODEs (math.CA)
subject: Logic (math.LO)
subject: FOS: Mathematics
subject: 03C64, 26E10, 32S45 (Primary) 30D60, 32B20 (Secondary)

description: We prove two main results on Denjoy-Carleman classes: (1) a composite function theorem which asserts that a function f(x) in a quasianalytic Denjoy-Carleman class Q, which is formally composite with a generically submersive mapping y=h(x) of class Q, at a single given point in the source (or in the target) of h, can be written locally as f(x) = g(h(x)), where g(y) belongs to a shifted Denjoy-Carleman class Q' ; (2) a statement on a similar loss of regularity for functions definable in the o-minimal structure given by expansion of the real field by restricted functions of quasianalytic class Q. Both results depend on an estimate for the regularity of an infinitely differentiable solution g of the equation f(x) = g(h(x)), with f and h as above. The composite function result depends also on a quasianalytic continuation theorem, which shows that the formal assumption at a given point in (1) propagates to a formal composition condition at every point in a neighbourhood.
description: 13 pages
A protective role for the lectin CD169/Siglec-1 against a pathogenic murine retrovirus
Creators: name: Uchil, Pradeep D
name: Ruoxi Pi
name: Haugh, Kelsey A
name: Ladinsky, Mark S
name: Ventura, John D
name: Barrett, Brad S
name: Santiago, Mario L
name: Bjorkman, Pamela J
name: Kassiotis, George
name: Sewald, Xaver
name: Mothes, Walther
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: subject: Genetics & Genomics
subject: Model organisms
subject: Immunology
subject: FOS: Clinical medicine
subject: Computational & Systems Biology

description: Lymph- and blood-borne retroviruses exploit CD169/Siglec-1-mediated capture by subcapsular sinus and marginal zone metallophilic macrophages for trans-infection of permissive lymphocytes. However, the impact of CD169-mediated virus capture on retrovirus dissemination and pathogenesis in vivo is unknown. In a murine model of the splenomegaly-inducing retrovirus Friend virus complex (FVC) infection, we find that while CD169 promoted draining lymph node infection, it limited systemic spread to the spleen. At the spleen, CD169-expressing macrophages captured incoming blood-borne retroviruses and limited their spread to the erythroblasts in the red pulp where FVC manifests its pathogenesis. CD169-mediated retroviral capture activated conventional dendritic cells 1 (cDC1s) and promoted cytotoxic CD8+ T cell responses, resulting in efficient clearing of FVC-infected cells. Accordingly, CD169 blockade led to higher viral loads and accelerated death in susceptible mouse strains. Thus, CD169 plays a protective role during FVC pathogenesis by reducing viral dissemination to erythroblasts and eliciting an effective cytotoxic T lymphocyte response via cDC1s.
Theory of tunneling spectroscopy in the Larkin-Ovchinnikov state
Creators: name: Tanaka, Y.
name: Asano, Y.
name: Ichioka, M.
name: Kashiwaya, S.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: A theory of the tunneling spectroscopy of normal metal / Larkin-Ovchinnikov (LO) state is presented by fully taking account of the periodic modulation of pair potentials in real space. The resulting tunneling spectra have characteristic line shapes with several maxima and minima reflecting minigap structures due to the periodic pair potentials. These features are qualitatively different from tunneling spectra of Fulde-Ferrell state and those of uniform $s$- and d-wave superconductors. On the basis of calculated results, we propose a method to identify the LO state in actual experiments.
description: 5 pages, 5 figures
Streptococcal dTDP-L-rhamnose biosynthesis enzymes: functional characterization and lead compound identification
Creators: name: Beek, Samantha L Van Der
name: Azul Zorzoli
name: Çanak, Ebru
name: Chapman, Robert N
name: Lucas, Kieron
name: Meyer, Benjamin H
name: Evangelopoulos, Dimitrios
name: Luiz Pedro S De Carvalho
name: Geert-Jan Boons
name: Dorfmueller, Helge C
name: Sorge, Nina M Van
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: Biochemistry & Proteomics
Genetics & Genomics
Structural Biology & Biophysics
Infectious Disease
Ecology,Evolution & Ethology
Metabolism
Computational & Systems Biology

description: Biosynthesis of the nucleotide sugar precursor dTDP-L-rhamnose is critical for the viability and virulence of many human pathogenic bacteria, including Streptococcus pyogenes (Group A Streptococcus; GAS), Streptococcus mutans and Mycobacterium tuberculosis. Streptococcal pathogens require dTDP-L-rhamnose for the production of structurally similar rhamnose polysaccharides in their cell wall. Via heterologous expression in S. mutans, we confirmed that GAS RmlB and RmlC are critical for dTDP-L-rhamnose biosynthesis through their action as dTDP-glucose-4,6-dehydratase and dTDP-4-keto-6-deoxyglucose-3,5-epimerase enzymes respectively. Complementation with GAS RmlB and RmlC containing specific point mutations corroborated the conservation of previous identified catalytic residues. Bio-layer interferometry was used to identify and confirm inhibitory lead compounds that bind to GAS dTDP-rhamnose biosynthesis enzymes RmlB, RmlC and GacA. One of the identified compounds, Ri03, inhibited growth of GAS, other rhamnose-dependent streptococcal pathogens as well as M. tuberculosis with an IC50 of 120-410 µM. Importantly, we confirmed that Ri03 inhibited dTDP-L-rhamnose formation in a concentration-dependent manner through a biochemical assay with recombinant rhamnose biosynthesis enzymes. We therefore conclude that inhibitors of dTDP-L-rhamnose biosynthesis, such as Ri03, affect streptococcal and mycobacterial viability and can serve as lead compounds for the development of a new class of antibiotics that targets dTDP-rhamnose biosynthesis in pathogenic bacteria.
Spin-orbit coupling and magnetic field dependence of carriers states in a self-assembled quantum dot
Creators: name: Gawarecki, Krzysztof
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In this work I investigate the influence of spin-orbit coupling on the magnetic field dependence of carrier states in a self-assembled quantum dot. I calculate the hole energy levels using the 6, 8 and 14 band k.p model. Through a detailed study within these models, I extract the information about the impact of various spin-orbital coupling channels in the hole p-shell. I also show that complicated magnetic field dependence of the hole p-shell resulting from numerical simulations, can be very well fitted using a phenomenological model. I compare the electron and hole g-factors calculated within 8 and 14 band k.p models and show that these methods give reasonably good agreement.
Additional file 5 of Personalising treatment plan quality review with knowledge-based planning in the TROG 15.03 trial for stereotactic ablative body radiotherapy in primary kidney cancer
Creators: name: Hardcastle, Nicholas
name: Cook, Olivia
name: Ray, Xenia
name: Moore, Alisha
name: Moore, Kevin L.
name: Pryor, David
name: Rossi, Alana
name: Foroudi, Farshad
name: Kron, Tomas
name: Siva, Shankar
Publisher: name: figshare
Year: 2021
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 5. KBP Quality Feedback Report: Case #51.
title: Effects of Sulfidation and Natural Organic Matter on the Deposition of Silver Nanoparticles
Creators: name: Chen, Yunqui
Publisher: name: University of Massachusetts Amherst
Year: 2015
Subjects: subject: Environmental Engineering
subject: FOS: Environmental engineering

description: Environmental transformation through sulfidation and complexation with natural organic matter (NOM) are two major factors that may affect the fate and transport of silver nanoparticles (AgNPs) in the aquatic systems by changing their dissolution, deposition, and surface properties. To understand the impact of sulfidation and NOM on the aggregation and deposition of AgNPs, a combination of dynamic light scattering and quartz crystal microgravimetry with dissipation monitoring was used. Polyvinylpyrrolidone (PVP)-capped AgNPs that were modified through sulfidation and/or complexed with NOM had a greater extent of deposition than unmodified PVP-AgNPs. Specifically, the deposition extent of sulfidized AgNPs in the presence of NOM, which was the most environmental-relevant form in this study, was 0.5 to almost 3 orders of magnitude greater than unmodified PVP-AgNPs. Bare-silica and NOM-coated substrates were used as a basis for differentiating the effect of substrate on the deposition of PVP-capped AgNPs. Bare-silica substrate was more favorable for the deposition of modified PVP-capped AgNPs (including sulfidized, NOM-complexed, and sulfidized in the presence of NOM) than NOMcoated substrates. Citrate-capped AgNPs were also investigated to study the effect of capping agents on the deposition and surface properties of AgNPs. Since deposition extent implicates the degree of susceptibility to removal by water treatment, citrate-capped AgNPs, which have 6 to 50 orders of magnitude less deposition than PVP-capped AgNPs, are more likely to persist in the aquatic environments.
Lettre de Nicolas Joseph Marcassus de Puymaurin à Jean-François Séguier, 1773-10-12
Creators: name: Marcassus de Puymaurin, Nicolas Joseph
name: De Puymaurin, Nicolas Joseph Marcassus
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Affaires du temps, politique
Recommandation

description: [transcription] Permettez-moi, Monsieur, de vous présenter Mr Lucas professeur de sculpture de notre académie. Il réunit aux talents de sa profession des connaissances, qui lui donnent la plus vive ardeur de connaître personnellement un des savants les plus célèbre de l'Europe, et d'admirer les collections précieuses qu'il a formées en antiquités et en histoire naturelle. Je vous supplie, Monsieur, de vouloir bien accueillir un empressement si juste et si légitime.

M. Lucas va passer quelque temps en Italie pour ébaucher le bas-relief de marbre de Carrare que la province a délibéré de faire placer à l'embouchure de notre nouveau canal.

J'ai l'honneur d'être avec un attachement respectueux, Monsieur, votre très humble et très obéissant serviteur.

Marcassus de Puymaurin

A Toulouse le 18 août 1773
description: [personnes citées] François Lucas
description: Source: [lieu de Conservation] Paris, Bibliothèque nationale de France [cote]NAF 6568, fol. 138-139
description: Source: ark:/12148/btv1b10509441r
Hamiltonian systems of Calogero type and two dimensional Yang-Mills theory
Creators: name: Gorsky, A.
name: Nekrasov, N.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We obtain integral representations for the wave functions of Calogero-type systems,corresponding to the finite-dimentional Lie algebras,using exact evaluation of path integral.We generalize these systems to the case of the Kac-Moody algebras and observe the connection of them with the two dimensional Yang-Mills theory.We point out that Calogero-Moser model and the models of Calogero type like Sutherland one can be obtained either classically by some reduction from two dimensional Yang-Mills theory with appropriate sources or even at quantum level by taking some scaling limit.We investigate large k limit and observe a relation with Generalized Kontsevich Model.
description: 34 pages,UUITP-6/93 and ITEP-20/93
A history of violence: insights into post-accretionary heating in carbonaceous chondrites from volatile element abundances, Zn isotopes, and water contents
Creators: name: Mahan, Brandon
name: Moynier, Frederic
name: Beck, Pierre
name: Pringle, Emily A.
name: Siebert, Julien
Publisher: name: arXiv
Year: 2017
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Carbonaceous chondrites (CCs) may have been the carriers of water, volatile and moderately volatile elements to Earth. Investigating the abundances of these elements, their relative volatility, and isotopes of state-change tracer elements such as Zn, and linking these observations to water contents, provide vital information on the processes that govern the abundances and isotopic signatures of these species in CCs and other planetary bodies. Here we report Zn isotopic data for 28 CCs (20 CM, 6 CR, 1 C2-ung, and 1 CV3), as well as trace element data for Zn, In, Sn, Tl, Pb, and Bi in 16 samples (8 CM, 6 CR, 1 C2-ung, and 1 CV3), that display a range of elemental abundances from case-normative to intensely depleted. We use these data, water content data from literature and Zn isotopes to investigate volatile depletions and to discern between closed and open system heating. Trace element data have been used to construct relative volatility scales among the elements for the CM and CR chondrites. From least volatile to most, the scale in CM chondrites is Pb-Sn-Bi-In-Zn-Tl, and for CR chondrites it is Tl-Zn-Sn-Pb-Bi-In. These observations suggest that heated CM and CR chondrites underwent volatile loss under different conditions to one another and to that of the solar nebula, e.g. differing oxygen fugacities. Furthermore, the most water and volatile depleted samples are highly enriched in the heavy isotopes of Zn. Taken together, these lines of evidence strongly indicate that heated CM and CR chondrites incurred open system heating, stripping them of water and volatiles concomitantly, during post-accretionary shock impact(s).
description: 4 tables, 5 figures
Additional file 12: of De novo transcriptome assembly of Pueraria montana var. lobata and Neustanthus phaseoloides for the development of eSSR and SNP markers: narrowing the US origin(s) of the invasive kudzu
Creators: name: Haynsen, Matthew
name: Vatanparast, Mohammad
name: Mahadwar, Gouri
name: Zhu, Dennis
name: Moger-Reischer, Roy
name: Doyle, Jeff
name: Crandall, Keith
name: Egan, Ashley
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Plant Biology

description: Figure S4. Delta K of STRUCTURE run (K = 3). Plot of Delta K for STRUCTURE analyses from K = 2 through K = 9, with K = 3 seen as the optimal number of genetic clusters. (PDF 18 kb)
Nanomechanics of CNTs for Sensor Application
Creators: name: Wagner, C.
name: Hartmann, S.
name: Wunderle, B.
name: Schuster, J.
name: Schulz, S. E.
name: Gessner, T.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A nanoscopic simulation for an acceleration sensor is aimed based on the piezoresistive effect of carbon nanotubes (CNTs). Therefore, a compact model is built from density functional theory (DFT), compared with results of molecular dynamics (MD) that describes the mechanics of carbon nanotubes in a parameterized way. The results for the interesting kind of CNTs [(6,3) and (7,4)] within the two approaches agree in a satisfying way, when DFT-calculations are performed with atomic configurations obtained by MD geometry optimization. Geometry optimization yields the Poisson ratio for CNTs. Thus, values from MD and DFT are compared. The simulation finally aims the modeling of the conductive behavior of CNTs when strain is applied, but this needs further verification. Here, we present the prediction of the tight binding model for suitable CNTs.
description: 5 pages, 4 figures, 2 tables
The Global-Normal Disk Oscillations and the Persistent Low Frequency QPO in X-ray Binaries
Creators: name: Titarchuk, Lev
name: Osherovich, Vladimir
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We suggest that persistent low-frequency quasi-periodic oscillations (QPOs) detected in X-ray, ultraviolet, optical energy ranges the black hole (BH) sources XTE J1118+480, GRO J1655-40 LMC X-1 at ~ 0.1 Hz, and QPOs in HZ Her/Her X-1 at ~ 0.05 Hz and in Neutron Star (NS) binaries 4U 1323-62, 4U 1746-31 and EXO 0748-76 at ~ 1 Hz are caused by the global disk oscillations in the direction normal to the disk (normal mode). We argue that these disk oscillations are a result of the gravitational interaction between the central compact object and the disk. A small displacement of the disk from the equatorial plane results in a linear gravitational restoring force opposite to this displacement. Our analysis shows that the frequency of this mode is a function of the mass of the central object and it also depends on the inner and outer radii of the disk which in turn are related to the rotation period of the binary system. We derive an analytical formula for the frequency of the normal disk mode and show that these frequencies can be related to the persistent lower QPO frequencies observed in the NS and BH sources. We offer a new independent approach to the black hole mass determination by interpreting this low QPO frequency as the global disk oscillation frequency. The implementation of this method combined with the independent method which uses the X-ray energy spectra (Shrader & Titarchuk 1999) results in stringent constraints for the black hole masses.
description: 14 pages, 1 figure, to appear in the Astrophysical Journal Letters
Comparing the fractal basins of attraction in the Hill problem with oblateness and radiation
Creators: name: Zotos, Euaggelos E.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: The basins of convergence, associated with the roots (attractors) of a complex equation, are revealed in the Hill problem with oblateness and radiation, using a large variety of numerical methods. Three cases are investigated, regarding the values of the oblateness and radiation. In all cases, a systematic and thorough scan of the complex plane is performed in order to determine the basins of attraction of the several iterative schemes. The correlations between the attracting domains and the corresponding required number of iterations are also illustrated and discussed. Our numerical analysis strongly suggests that the basins of convergence, with the highly fractal basin boundaries, produce extraordinary and beautiful formations on the complex plane.
description: Published in Astrophysics and Space Science (A&SS) journal
Anomalous Josephson effect in p-wave dirty junctions
Creators: name: Asano, Yasuhiro
name: Tanaka, Yukio
name: Kashiwaya, Satoshi
Publisher: name: arXiv
Year: 2006
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The Josephson effect in p-wave superconductor / diffusive normal metal / p-wave superconductor junctions is studied theoretically. Amplitudes of Josephson currents are several orders of magnitude larger than those in s-wave junctions. Current-phase (J-ϕ) relations in low temperatures are close to those in ballistic junctions such as J\propto\sin(ϕ/2) and J\proptoϕeven in the presence of random impurity potentials. A cooperative effect between the midgap Andreev resonant states and the proximity effect causes such anomalous properties and is a character of the spin-triplet superconductor junctions.
description: 4 pages, 4 figures
Additional file 1 of Decision-making autonomy of women and other factors of anemia among married women in Ethiopia: a multilevel analysis of a countrywide survey
Creators: name: Tiruneh, Fentanesh Nibret
name: Asres, Degnet Teferi
name: Tenagashaw, Mesfin Wogayehu
name: Assaye, Hirut
Publisher: name: figshare
Year: 2021
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 1: Table 1. Multicollinearity examination.
Additional file 12: of Transcriptomic analysis and mutational status of IDH1 in paired primary-recurrent intrahepatic cholangiocarcinoma
Creators: name: C. Peraldo-Neia
name: P. Ostano
name: G. Cavalloni
name: Y. Pignochino
name: D. Sangiolo
name: L. De Cecco
name: E. Marchesi
name: D. Ribero
name: A. Scarpa
name: A. De Rose
name: A. Giuliani
name: F. Calise
name: C. Raggi
name: P. Invernizzi
name: M. Aglietta
name: G. Chiorino
name: F. Leone
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified

description: Table S9. Sanger sequencing of IDH1 exon 4.Â (DOCX 15 kb)
Tachyon Condensates and String Theoretic Inflation
Creators: name: Raiten, Eric
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Cosmological solutions of the beta function equations for the background fields of the closed bosonic string are investigated at the one-loop level. Following recent work of Kostelecky and Perry, it is assumed that the spatial sections of the space-time are conformally flat. Working in the sigma-model frame, the non-trivial tachyon potential is utilized to determine solutions with sufficient inflation to solve the smoothness and flatness problems. The graceful exit and density perturbation constraints can also be successfully implemented.
description: FERMI-PUB 93/074-T, harvmac, 16 pages
Hypertension and one-year risk of all-cause mortality among women with treated HIV in the United States
Creators: name: Ramirez, C.
name: Anastos, K.
name: Adimora, A.A.
name: Cohen, M.H.
name: Konkle-Parker, D.
name: Brown, T.T.
name: Edmonds, A.
name: Kassaye, S.
name: Westreich, D.
name: Breger, T.L.
name: Jones, D.L.
name: Cole, S.R.
name: Tien, P.C.
name: Sadinski, L.M.
name: D'Souza, G.
name: Taylor, T.N.
name: Ofotokun, I.
Publisher: name: Lippincott Williams and Wilkins
Year: 2023

description: Objective: Hypertension is a critical cause of cardiovascular disease, and women with HIV have a higher prevalence of hypertension than women without HIV. The relationship between hypertension and mortality has not been well characterized in women with treated HIV. Here, we estimate the effect of hypertension on 1-year risk of all-cause mortality among women with HIV on antiretroviral therapy (ART) in the United States. Design: An analysis of multicenter, observational cohort data from the Women's Interagency HIV Study (WIHS) collected between 1995 and 2019. Methods: We included women with HIV who reported ever using ART. We used parametric g-computation to estimate the effect of hypertension (SBP ≥140 mmHg, DBP ≥90 mmHg, or use of hypertensive medication) on all-cause mortality within 1 year of a WIHS visit. Results: Among 2929 unique women, we included 57 034 visits with a median age of 45 (interquartile range: 39, 52) years. Women had hypertension at 34.5% of visits, and 641 deaths occurred within 1 year of a study visit. Comparing women at visits with hypertension to women at visits without hypertension, the standardized 1-year risk ratio for mortality was 1.16 [95% confidence interval (95% CI): 1.01-1.33]. The risk ratios were higher in Hispanic (risk ratio: 1.23, 95% CI: 0.86-1.77) and non-Hispanic black women (risk ratio: 1.19, 95% CI: 1.04-1.37) and lower in non-Hispanic white women (risk ratio: 0.93, 95% CI: 0.58-1.48). Conclusion: Among women with treated HIV, those with hypertension, compared with those without, had an increased 1-year risk of all-cause mortality.
Identifying extrinsic versus intrinsic drivers of variation in cell behavior in human iPSC lines from healthy donors
Creators: name: Vigilante, Alessandra
name: Laddach, Anna
name: Moens, Nathalie
name: Meleckyte, Ruta
name: Leha, Andreas
name: Arsham Ghahramani
name: Culley, Oliver J
name: Kathuria, Annie
name: Hurling, Chloe
name: Vickers, Alice
name: Wiseman, Erika
name: Tewary, Mukul
name: Zandstra, Peter W
name: HipSci Consortium
name: Durbin, Richard
name: Fraternali, Franca
name: Stegle, Oliver
name: Birney, Ewan
name: Luscombe, Nicholas M
name: Danovi, Davide
name: Watt, Fiona M
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: Genetics & Genomics
Gene Expression
Tumour Biology
Computational & Systems Biology

description: Large cohorts of human induced pluripotent stem cells (iPSCs) from healthy donors are a potentially powerful tool for investigating the relationship between genetic variants and cellular behavior. Here, we integrate high content imaging of cell shape, proliferation, and other phenotypes with gene expression and DNA sequence datasets from over 100 human iPSC lines. By applying a dimensionality reduction approach, Probabilistic Estimation of Expression Residuals (PEER), we extracted factors that captured the effects of intrinsic (genetic concordance between different cell lines from the same donor) and extrinsic (cell responses to different fibronectin concentrations) conditions. We identify genes that correlate in expression with intrinsic and extrinsic PEER factors and associate outlier cell behavior with genes containing rare deleterious non-synonymous SNVs. Our study, thus, establishes a strategy for examining the genetic basis of inter-individual variability in cell behavior.
Galileon string measure and other modified measure extended objects
Creators: name: Vulfs, T. O.
name: Guendelman, E. I.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We show that it is possible to formulate string theory as a "Galileon string theory". The galileon field $χ$ enters in the definition of the integration measure in the action. Following the methods of the modified measure string theory, we find that the final equations are again those of Polyakov. Moreover, the string tension appears again as an additional dynamical degree of freedom. At the same time the theory satisfies all requirements of the galileon higher derivative theory at the action level while the equations of motion are still of the second order. A galileon symmetry is displayed explicitly in the conformal string worldsheet frame. Also we define the galileon gauge transformations. Generalizations to branes with other modified measures are discussed.
description: 8 pages
Additional file 1 of Healthcare workers preparedness for COVID-19 pandemic in the occupied Palestinian territory: a cross-sectional survey
Creators: name: Alser, Osaid
name: Alghoul, Heba
name: Alkhateeb, Zahra
name: Hamdan, Ayah
name: Albarqouni, Loai
name: Saini, Kiran
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Table S1. Study questionnaire.
Robustness of One-Dimensional Photonic Bandgaps Under Random Variations of Geometrical Parameters
Creators: name: Sozuer, H. S.
name: Sevim, K.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The supercell method is used to study the variation of the photonic bandgaps in one-dimensional photonic crystals under random perturbations to thicknesses of the layers. The results of both plane wave and analytical band structure and density of states calculations are presented along with the transmission cofficient as the level of randomness and the supercell size is increased. It is found that higher bandgaps disappear first as the randomness is gradually increased. The lowest bandgap is found to persist up to a randomness level of 55 percent.
description: Submitted to Physical Review B on April 8 2005
Risk factors for acute mental health symptoms and tobacco initiation in Coast Guard Responders to the Deepwater Horizon oil spill
Creators: name: Wang, J.H.
name: Thomas, D.L.
name: Denic-Roberts, H.
name: Engel, L.S.
name: Goodie, J.L.
name: Rusiecki, J.A.
Publisher: name: John Wiley and Sons Inc
Year: 2022

description: Acute mental health symptoms experienced during oil spill response work are understudied, especially among nonlocal responders. We assessed potential risk factors for acute mental health symptoms and tobacco initiation among U.S. Coast Guard responders to the 2010 Deepwater Horizon (DWH) oil spill who completed a deployment exit survey. Cross-sectional associations among responder characteristics, deployment-related stressors (deployment duration, timing, crude oil exposure, physical symptoms, injuries), and professional help-seeking for stressors experienced with concurrent depression/anxiety and tobacco initiation were examined. Log-binomial regression was used to calculate adjusted prevalence ratios (aPRs) and 95% confidence intervals. Sensitivity analyses excluded responders with a history of mental health conditions using health encounter data from the Military Health System Data Repository. Of the 4,855 responders, 75.5% were deployed from nonlocal/non-Gulf home stations, 5.8% reported concurrent depression and anxiety, and 2.8% reported the initiation of any tobacco product during oil spill response. Self-report of concurrent depression and anxiety was more prevalent among female responders and positively associated with longer deployments, crude oil exposure via inhalation, physical symptoms and injuries, and professional help–seeking during deployment, aPRs = 1.54–6.55. Tobacco initiation was inversely associated with older age and officer rank and positively associated with deployment-related stressors and depression/anxiety during deployment, aPRs = 1.58–4.44. Associations remained robust after excluding responders with a history of mental health– and tobacco–related health encounters up to 3 years before deployment. Depression, anxiety, and tobacco initiation were cross-sectionally associated with oil spill response work experiences among DWH responders, who largely originated outside of the affected community.