cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
“No pain, no gainz”? Performance and image-enhancing drugs, health effects and information seeking
Creators: name: Rowe, Rachel
name: Berger, Israel
name: Copeland, Jan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Background: A range of indicators point to an international increase in the prevalence of performance and image-enhancing drugs (PIEDs) use, predominantly among young men. Attention to PIEDs-related benefits, adverse health effects, information and health service access are needed. Methods: A cross-sectional survey of 605 men who inject PIEDs was conducted at nine primary needle and syringe programme locations across five local health districts in Sydney. Results: Among anabolic–androgenic steroids (AAS) users (n = 564), anger, rage or irritability (27%, 95%CI: 23.4–30.6) and sexual or genital problems (26.4%, 95%CI: 22.9–30.0) were the most commonly reported adverse health effects. Taking regular, longer breaks between AAS cycles were associated with reduced reports of some adverse effects. Approaching two-thirds of participants had told a doctor about using PIEDs (63.1%, 95%CI: 59.1–67.1). However, as length of time since first injecting PIEDs increased, participants’ perceptions of doctors as reliable information sources decreased (rho = −0.10, p = 0.04). Reliance on lay information sources was very common, particularly among people who spoke languages other than English. Conclusions: This study supports providing information on cycle lengths and break periods as part of standard PIEDs-related harm reduction guidelines. Safe injecting and dosage education through peer networks or steroid clinics may be useful strategies.
IV: Middlewich: the evidence of Roman coin loss
Creators: name: Shotter, David C A
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 75, 51-60
description: Property developments in the Middlewich area have recently led to the accumulation of a substantial collection of Roman coins. These are used in this paper to argue for, inter alia, pre- and early Flavian occupation and the presence of a legionary garrison.
Berkeley Open Extended Reality Recordings 2023 (BOXRR-23): 4.7 Million Motion Capture Recordings from 105,852 Extended Reality Device Users
Creators: name: Nair, Vivek
name: Guo, Wenbo
name: Wang, Rui
name: O'Brien, James F.
name: Rosenberg, Louis
name: Song, Dawn
Publisher: name: arXiv
Year: 2023
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Extended reality (XR) devices such as the Meta Quest and Apple Vision Pro have seen a recent surge in attention, with motion tracking "telemetry" data lying at the core of nearly all XR and metaverse experiences. Researchers are just beginning to understand the implications of this data for security, privacy, usability, and more, but currently lack large-scale human motion datasets to study. The BOXRR-23 dataset contains 4,717,215 motion capture recordings, voluntarily submitted by 105,852 XR device users from over 50 countries. BOXRR-23 is over 200 times larger than the largest existing motion capture research dataset and uses a new, highly efficient purpose-built XR Open Recording (XROR) file format.
description: Learn more at https://rdi.berkeley.edu/metaverse/boxrr-23
Evaluation of the performance of high temperature conversion reactors for compound-specific oxygen stable isotope analysis
Creators: name: Hitzfeld, Kristina L.
name: Gehre, Matthias
name: Hans-Hermann Richnow
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: In this study conversion conditions for oxygen gas chromatography high temperature conversion (HTC) isotope ratio mass spectrometry (IRMS) are characterised using qualitative mass spectrometry (IonTrap). It is shown that physical and chemical properties of a given reactor design impact HTC and thus the ability to accurately measure oxygen isotope ratios. Commercially available and custom-built tube-in-tube reactors were used to elucidate (i) by-product formation (carbon dioxide, water, small organic molecules), (ii) 2nd sources of oxygen (leakage, metal oxides, ceramic material), and (iii) required reactor conditions (conditioning, reduction, stability). The suitability of the available HTC approach for compound-specific isotope analysis of oxygen in volatile organic molecules like methyl tert-butyl ether is assessed. Main problems impeding accurate analysis are non-quantitative HTC and significant carbon dioxide by-product formation. An evaluation strategy combining mass spectrometric analysis of HTC products and IRMS 18O/16O monitoring for future method development is proposed.
Expressing and Inferring Action Carefulness in Human-to-Robot Handovers
Creators: name: Lastrico, Linda
name: Duarte, Nuno Ferreira
name: Carfì, Alessandro
name: Rea, Francesco
name: Sciutti, Alessandra
name: Mastrogiovanni, Fulvio
name: Santos-Victor, José
Publisher: name: arXiv
Year: 2023
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Implicit communication plays such a crucial role during social exchanges that it must be considered for a good experience in human-robot interaction. This work addresses implicit communication associated with the detection of physical properties, transport, and manipulation of objects. We propose an ecological approach to infer object characteristics from subtle modulations of the natural kinematics occurring during human object manipulation. Similarly, we take inspiration from human strategies to shape robot movements to be communicative of the object properties while pursuing the action goals. In a realistic HRI scenario, participants handed over cups - filled with water or empty - to a robotic manipulator that sorted them. We implemented an online classifier to differentiate careful/not careful human movements, associated with the cups' content. We compared our proposed "expressive" controller, which modulates the movements according to the cup filling, against a neutral motion controller. Results show that human kinematics is adjusted during the task, as a function of the cup content, even in reach-to-grasp motion. Moreover, the carefulness during the handover of full cups can be reliably inferred online, well before action completion. Finally, although questionnaires did not reveal explicit preferences from participants, the expressive robot condition improved task efficiency.
description: PREPRINT VERSION Accepted for publication at the 2023 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS2023)
Effect of variety on content of bioactive phenolic compounds in common elder (Sambucus nigra L.)
Creators: name: Naděžda Vrchotová
name: Dadáková, Eva
name: Aleš Matějíček
name: Tříska, Jan
name: Jiří Kaplan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Inorganic Chemistry
subject: Plant Biology
subject: 60506 Virology

description: The inflorescence of common elder (Sambucus nigra L., Adoxaceae) is known to be rich in phenolic compounds. The content of five selected phenolic compounds (rutin, chlorogenic acid, isoquercitrin, isorhamnetin-3-O- rutinoside and dicaffeoylquinic acid) was determined in methanolic extracts from flowers and floral stems by HPLC in samples obtained from 20 varieties of S. nigra cultivated in Czech Republic. In all samples, there were determined rutin (11–54 mg/g), chlorogenic acid (23–46 mg/g), isoquercitrin (0.6–18 mg/g), isorhamnetin-3-O-rutinoside (3–10 mg/g), calculated on air-dried material. The content of dicaffeoylquinic acid was 0–13 mg/g of air-dried material. The amount of the analysed compounds in floral stems was lower than the flowers. The results are a unique set of information on the content of main phenolics in the inflorescence of cultured elderberry varieties.
Recent discoveries at Vale Crucis Abbey
Creators: name: Richardson, G C
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 3, 175-177
description: Five tombstones discovered at Vale [sic] Crucis Abbey in Wales, built into the floor of the dormitory, had apparently been used to infill hollows over the vaulted roof of the chapter house below. Three of the stones and their inscriptions are described; the fourth and fifth are fragmentary. The three larger stones are considered of likely 13th century date; one includes the name 'Madog' and was perhaps the tomb of the founder of the abbey, Madog ap Gryffydd Maelor. LD
Synthesis and crystal structures of cobalt(II), cadmium(II), and zinc(II) complexes of 4-nitro phenylcyanamide: enhancing the biological properties through bound to human serum albumin
Creators: name: Jazestani, Mehdi
name: Chiniforoshan, Hossein
name: Tabrizi, Leila
name: McArdle, Patrick
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Metal complexes of the type [Co(phen)2(4-NO2pcyd)2].CH3OH, 1, [Zn(phen)2(4-NO2pcyd)2].CH3OH, 2, [Cd(phen)2(4-NO2pcyd)2], and 3, (phen = 1,10-phenanthroline, 4-NO2pcyd = 4-nitro phenylcyanamide) have been studied. The synthesis, characterization, and the biological activities of complexes 1-3 have been investigated. The geometries of complexes 1-3 were confirmed by single-crystal X-ray crystallography. The interactions of complexes 1-3 with human serum albumin (HSA) were studied using fluorescence and circular dichroism spectroscopy. The thermodynamic studies have showed the reaction for the binding of complexes 1-3 with HSA is hydrophobic (ΔH0 ˂ 0 and ΔS0 > 0). The in vitro cytotoxic potential of complexes 1-3 and their complexes with HSA were examined. The complexes 1-3 with HSA enhance about 3-fold cytotoxicity in cancer cells lines.
BindingDB Entry 12139: COMPOSITIONS AND METHODS FOR TREATING, PREVENTING OR REVERSING AGE-ASSOCIATED INFLAMMATION AND DISORDER
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: LINE-1 retrotransposable element ORF1 protein, Brown University, Affinity

description: Small molecule binding data for protein LINE-1 retrotransposable element ORF1 protein
ATS-STEM Research Methodology and Evaluation Guidelines
Creators: name: Fernández-Morante, C.
name: Fernández De La Iglesia., J.C.
name: Cebreiro López, B.
name: Latorre Ruiz, E.
name: Mareque-León, F.
Publisher: name: Zenodo
Year: 2022
Subjects: Educational research
Research design and instrumemts
ATS-STEM Project
STEM Education
Digital Assessment
Globalized education
Problem-based teaching

description: This methodological research design has been developed within the framework of work package 5 of the European project "Assessment of Transversal Skills in STEM (ATS-STEM) and has been carried out by the educational technology group of the University of Santiago de Compostela (http://tecnoeduc.es) and are available from the project website: https://www.atsstem.eu/resources/ It contains the complete methodological design and all the instruments necessary to implement the evaluative research design created within the framework of work package 5 of the project. the purpose of this design is to ensure the elaboration of a scientific research report documenting the results obtained in the pilot conducted in schools in 7 European countries. this instrument was developed so that all participating researchers in the 7 countries would share the same common framework and tools, thus ensuring rigor and homogeneity in the quantitative and qualitative data collection processes and in the elaboration of the national research reports. this publication is complemented by the transnational research report carried out within the framework of the project, which will also be published.
Entropy-MCMC: Sampling from Flat Basins with Ease
Creators: name: Li, Bolian
name: Zhang, Ruqi
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Bayesian deep learning counts on the quality of posterior distribution estimation. However, the posterior of deep neural networks is highly multi-modal in nature, with local modes exhibiting varying generalization performance. Given a practical budget, targeting at the original posterior can lead to suboptimal performance, as some samples may become trapped in "bad" modes and suffer from overfitting. Leveraging the observation that "good" modes with low generalization error often reside in flat basins of the energy landscape, we propose to bias sampling on the posterior toward these flat regions. Specifically, we introduce an auxiliary guiding variable, the stationary distribution of which resembles a smoothed posterior free from sharp modes, to lead the MCMC sampler to flat basins. By integrating this guiding variable with the model parameter, we create a simple joint distribution that enables efficient sampling with minimal computational overhead. We prove the convergence of our method and further show that it converges faster than several existing flatness-aware methods in the strongly convex setting. Empirical results demonstrate that our method can successfully sample from flat basins of the posterior, and outperforms all compared baselines on multiple benchmarks including classification, calibration, and out-of-distribution detection.
BindingDB Entry 12138: INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Tyrosine-protein phosphatase non-receptor type 2, Bristol-Myers Squibb, Affinity

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 2, Uniprot P17706
The distribution of Bronze Age metalwork from Lancashire and Cheshire
Creators: name: Davey, Peter J
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 59, 1-13
description: Makes a statistical analysis of the distribution of finds by altitude and by solid geology, the second giving more positive results than the first. The pattern suggests EBA-MBA settlement on coastal sites and valley floors, with increasing colonization of the upper reaches of rivers in LBA. However, cemeteries of the earlier period were often on higher ground. The distribution bears little relation to 'trade routes', and nearly all the objects are of local (N English) manufacture with almost no continental or Irish imports.
V: The Tatton Park project, part 2: the medieval estates, settlements and halls
Creators: name: Higham, Nick J
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 75, 61-133
description: A second report on archaeological investigations and research undertaken within the eighteenth-century park. This paper includes a topographical survey of the estate, parish, lordship and landscape of Tatton c 1000---1400, including data from the excavation of the village site and an archaeological survey of the Old Hall. Also discusses Tatton's association with the Massy and Brereton families.
I: The Iron Age of north-west England: a socio-economic model
Creators: name: Matthews, K J
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 76, 1-51
description: This paper reviews the evidence for IA settlement and society in the area, as far north as the Ribble. Models based on south-eastern England are explicitly rejected, as is the view that the region was populated by an egalitarian farming society. Rather there seems to have been a politico-economic elite who based their wealth on salt and engaged in trade with the continent via an emporium at Meols. Includes:
Spectroscopic, electrochemical, and structural aspects of the Ce(IV)/Ce(III) DOTA redox couple chemistry in aqueous solutions
Creators: name: Moiseev, Yulia
name: Ben-Eliyahu, Yeshayahu
name: Audras, Matthieu
name: Berthon, Laurence
name: Moisy, Philippe
name: Bettelheim, Armand
name: Zilbermann, Israel
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology
subject: Inorganic Chemistry
subject: Computational Biology

description: The redox potential of the Ce(IV)/Ce(III) DOTA is determined to be 0.65 V versus SCE, pointing out a stabilization of ~13 orders of magnitude for the Ce(IV)DOTA complex, as compared to Ce(IV)aq. The Ce(III)DOTA after electrochemical oxidation yields a Ce(IV)DOTA complex with a t1/2 ~3 h and which is suggested to retain the “in cage” geometry. Chemical oxidation of Ce(III)DOTA by diperoxosulfate renders a similar Ce(IV)DOTA complex with the same t1/2. From the electrochemical measurements, one calculates logK (Ce(IV)DOTA2−) ~ 35.9. Surprisingly, when Ce(IV)DOTA is obtained by mixing Ce(IV)aq with DOTA, a different species is obtained with a 2 : 1(M : L) stoichiometry. This new complex, Ce(IV)DOTACe(IV), shows redox and spectroscopic features which are different from the electrochemically prepared Ce(IV)DOTA. When one uses thiosulfate as a reducing agent of Ce(IV)DOTACe(IV), one gets a prolonged lifetime of the latter. The reductant seems to serve primarily as a coordinating ligand with a geometry which does not facilitate inner sphere electron transfer. The reduction process rate in this case could be dictated by an outer sphere electron transfer or DOTA exchange by S2O32−. Both Ce(IV)DOTA and Ce(IV)DOTACe(IV) have similar kinetic stability and presumably decompose via decarboxylation of the polyaminocarboxylate ligand.
BindingDB Entry 12179: UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Ubiquitin carboxyl-terminal hydrolase 1, Simcere Zaiming Pharmaceutical Co., Affinity

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Ubiquitin carboxyl-terminal hydrolase 1, Uniprot O94782, P05177, P08684, P10635, P11712, and P33261
II: Further inscribed Roman salt pans from Shavington, Cheshire
Creators: name: Penney, Stephen H
name: Shotter, David C A
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 76, 53-61
description: The discovery of two more ?fourth-century salt pans confirms Roman salt production at the site and may represent its culmination rather than its beginning. The inscription FL VIVENTIUS on one pan is thought to refer to the same individual as the inscription VIVENTIUS EPISCOPUS on the pan found in 1993. It is thought to imply saltworks under the control of the church and to add to the small collection of evidence for early Christianity in the north Midlands. The saltworks may have continued in production into the sixth or seventh century. One of the authors of this article died before its publication and there is:
III: St John's Church and the early history of Chester
Creators: name: Matthews, S
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 76, 63-80
description: Speculative paper arguing that the reference to Chester being `waste' in 893 was not indicative of its status throughout the Dark Ages but a temporary state of affairs. It is argued that in the sub-Roman period it was the seat of secular and religious authority straddling the River Dee, supported by the estate at Holt-Farndon and the Cheshire salt industry respectively. After the imposition of Mercian rule the western boundary of this unit was delimited by Wat's Dyke. The traditional foundation date of 685 for St John's is accepted (indeed, it is thought it may represent a re-foundation) and the church became the see of a chorepiscopus supported by some of the land west of the Dee. Chester's pre-existing importance led to the creation of the burh in 907 rather than vice versa.
BindingDB Entry 12178: TREATMENT OF MYELOPROLIFERATIVE DISEASES AND DISORDERS WITH INHIBITORS OF BET FAMILY BDII BROMODOMAIN
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Bromodomain-containing protein 4 [368-440], Poseidon Innovation 1, Affinity

description: Small molecule binding data for protein Bromodomain-containing protein 4 [368-440], Uniprot O60885
Spectroscopic, electrochemical and structural aspects of the Ce(IV)/Ce(III) DOTA redox couple chemistry in aqueous solutions
Creators: name: Moiseev, Yulia
name: Ben-Eliyahu, Yeshayahu
name: Audras, Matthieu
name: Berthon, Laurent
name: Moisy, Philippe
name: Bettelheim, Armand
name: Zilbermann, Israel
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology
subject: Inorganic Chemistry
subject: Computational Biology

description: The redox potential of the Ce(IV)/Ce(III) DOTA is determined to be 0.67 V vs SCE, pointing out a stabilization of ~13 orders of magnitude for the Ce(IV)DOTA complex, as compared to Ce(IV)aq. The Ce(III)DOTA after electrochemical oxidation yields a Ce(IV)DOTA complex with a t1/2 ~3 h and which is suggested to retain the “in cage” geometry. Chemical oxidation of Ce(III)DOTA by diperoxosulfate renders a similar Ce(IV)DOTA complex with the same t1/2. From the electrochemical measurements one calculates logK (Ce(IV)DOTA2−) ~ 35.9. Surprisingly, when Ce(IV)DOTA is obtained by mixing Ce(IV)aq with DOTA, a different species is obtained with a 2:1(M:L) stoichiometry. This new complex, Ce(IV)DOTACe(IV), shows redox and spectroscopic features which are different from the electrochemically prepared Ce(IV)DOTA. When one uses thiosulphate as a reducing agent of Ce(IV)DOTACe(IV), one gets a prolonged lifetime of the latter. The reductant seems to serve primarily as a coordinating ligand with a geometry which does not facilitate inner sphere electron transfer. The reduction process rate in this case could be dictated by an outer sphere electron transfer or DOTA exchange by S2O32−. Both Ce(IV)DOTA and Ce(IV)DOTACe(IV) have similar kinetic stability and presumably decompose via decarboxylation of the polyaminocarboxylate ligand.
New 3D and 2D supramolecular heteroleptic palladium(II) dithiocarbamates as potent anticancer agents
Creators: name: Shahan Zeb Khan
name: Amir, Muhammad Kashif
name: Rashda Abbasi
name: Tahir, Muhammad Nawaz
name: Zia-Ur-Rehman
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Three new heteroleptic palladium(II) dithiocarbamates with better in vitro anticancer activity than cisplatin were synthesized and characterized by different analytical techniques, elemental analysis, FTIR, NMR, and single crystal X-ray diffraction analysis. The Pd center is chelated by dithiocarbamate ligand {4-benzylpiperazine-1-carbodithioate (1) and (3) or (4-(2-methoxyphenyl)piperazine-1-carbodithioate (2)}, triorganophosphine {tris-(4-flourophenyl)-phosphine (1) and (2) or tris-(4-chlorophenyl)phosphine (3)}, and a chloro-group, resulting in a square planar geometry. The packing diagram reveals a 3D network (1 and 2) and a 2D network (3) composed of various 1D chains in which the molecules are linked via hydrogen bonds (1–3) and halide⋯π (1, 3) interactions. The anticancer activities of complexes against HeLa cell line varies in the sequence 2 (23.438 μM) > 1 (38.293 μM) > 3 (47.554 μM) > cisplatin (78.075 μM). The cytotoxicity of these complexes is due to their strong induction of oxidative stress and DNA-damage ability leading to apoptosis.
Employees' Well-Being and Attitudes during Work Hours In Brunei Public Sector
Creators: name: Salleh, Noor Maya
Publisher: name: Zenodo
Year: 2024
Subjects: well-being
work hours
public sector

description: The purpose of this study is to investigate relationship between well-being and attitudes of civil servants during working hours. A cross-sectional research was conducted (n=405) across ministries in Brunei from non-executive services to executive services. A validated 14-item Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS) using a 5-point Likert scale was used to measure employees’ well-being and working hours items were adapted from validated BAuA-Working Time Survey (BAuA-WTS) measurements. The study found positive correlations between well-being and attitudes during work hours. This study can pave a pathway for policymakers to explore possible policies and strategies to strengthen employees’ well-being at work.
BindingDB Entry 12177: ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KAWASAKI DISEASE
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Alpha-protein kinase 1, Shanghai Yao Yuan Biotechnology Co., Affinity

description: Small molecule binding data for protein Alpha-protein kinase 1, Uniprot Q96QP1
BindingDB Entry 12176: Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said substituted indazoles, and use of said substituted indazoles to produce drugs
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Interleukin-1 receptor-associated kinase 4, Bayer Pharma Aktiengesellschaft, Affinity

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot Q69FE3 and Q9NWZ3
On a sculptured stone with a runic inscription in Cheshire
Creators: name: Browne, G F
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 3, 178-184
description: Article describing a sculptured stone of the Saxon period found amongst the building materials of a church at Upton near Birkenhead, pulled down in 1887. The church had itself been built in 1813 from the materials of a church at Overchurch that had fallen into ruin. Some interpretations of the runic inscription on the stone are discussed and the most likely reading is presented. The stone is apparently a memorial to Aethelmund. LD
A mixed experimental and theoretical study on chelidamate copper(II) complex with 4-methylpyrimidine
Creators: name: Vural, Hatice
name: İbrahim Uçar
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: A new chelidamate complex, [Cu(chel)(H2O)2(mpd)] (chel = chelidamate; mpd = 4-methylpyrimidine), has been synthesized and characterized through a combination of single crystal X-ray analysis, electron paramagnetic resonance (EPR), ultraviolet-visible (UV-vis), and fourier transform infrared spectroscopy (FT-IR). The complex has six-coordinate distorted octahedral geometry around Cu(II). The theoretical vibrational frequencies and optimized geometric parameters (bond lengths and angles) have been calculated using Density Functional Theory (DFT)/B3LYP and Hartree Fock quantum chemical methods with 6-31G(d, p) basis set by Gaussian 09W software. The EPR spectrum of the compound showed that the paramagnetic center has rhombic symmetry. The EPR studies were carried out using the following unrestricted hybrid density functionals: B3LYP, CAM-B3LYP, HSEH1PBE, WB97XD, MPW1PW91, and BPV86. The UV–vis absorption spectra have been examined in different media and compared with the calculated one using TD-DFT method by applying the polarizable continuum model. Natural bond orbital property of complex has been performed by DFT/B3LYP with 6-31G (d, p) basis set.
DiSSI: GlasWeeAsian evaluation tools
Creators: name: Ross, Kirsty
name: Bhatti, Saeeda
name: Birnie, Ingeborg
name: Essex, Jane
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 390402
subject: Education assessment and evaluation
classificationCode: 390304
subject: Primary education

description: These are the pre- and post-workshop evaluation cards for the GlasWeeAsian Plant Explorers workshop. They are available in multiple languages. They received ethical approval from the University of Strathclyde for anonymous data collection from our workshops. 

How to use the resources

 Print the designs, double sided, onto plain paper or card (no coating) 
 Hand out cards at the start of the workshop, asking the attendees to respond to the prompt question and complete some light demographic information
 Set aside and deliver the workshop
 At the end, ask the attendees to flip over the postcards and complete the reverse side

In theory, you should see an increase in precision, vocabulary, and knowledge after the workshop. We typically get ours printed on A6 or A5 card flyers at our local print shop, rather than using a home printer.

Attribution
Kirsty Ross was responsible for the original text and graphical design of all postcards. Saeeda Bhatti sought out and coordinated other translators and their contributions. The following individuals provided our translations:

 English: Kirsty Ross
 Gaelic: Inge Birnie
BindingDB Entry 12174: HIF-1α inhibitor, preparation method therefor, and pharmaceutical composition for preventing or treating angiogenesis-associated eye disease, containing same as active ingredient
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Hypoxia-inducible factor 1-alpha, Seoul National University, Affinity

description: Small molecule binding data for protein Hypoxia-inducible factor 1-alpha, Uniprot Q16665
BindingDB Entry 12173: Pyrrolo[2,1-f][1,2,4]triazine derivatives serving as selective HER2 inhibitors and application thereof
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-2, and Receptor tyrosine-protein kinase erbB-4, Medshine Discovery, Affinity

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-2, and Receptor tyrosine-protein kinase erbB-4, Uniprot P00533, P04626, P05177, P08684, P10635, P11712, P33261, and Q15303
Eupyrgota vespiformis
Creators: name: Korneyev, V. A.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Pyrgotidae
Eupyrgota
Eupyrgota vespiformis

description: Eupyrgota vespiformis (Enderlein, 1942) (fig. 7) M a t e r i a l (additional to published). Kenya: Western Province, Kakamega Forest, 0°14.13’ N, 34°51.87’ E, Malaise trap, 9– 16.04.2000, 1 ♀ (Copeland) (NMKE). R e m a r k s. This specimen shows several characters supplementary to the redescription in Korneyev (2006 b: 124): parafacial dark brown to black, usually with yellow spot at level of antennal base, shining, often wrinkled (fig. 7, 2, 3); fronto-orbital plates very wide and shining, smooth or wrinkled, as wide as or wider than matt frontal vitta (fig. 7, 4); eversible membrane half as long as dorsal side of oviscape (fig. 7, 6). Рис. 7. Eupyrgota vespiformis, ♀ (NMKE): 1 — общий вид, слева; 2–4 — голова (2 — спереди слева; 3 — слева спереди; 4 — дорсально); 5 — крыло; 6–7 — брюшко (6 — слева; 7 — дорсально).
description: Published as part of Korneyev, V. A., 2014, Pyrgotid Flies Assigned To Apyrgota. I. New Species And Synonyms In Eupyrgota (S. Str.) (Diptera, Pyrgotidae), With The Description Of A New Subgenus, pp. 111-128 in Vestnik Zoologii 48 (2) on page 125, DOI: 10.2478/vzoo-2014-0012, http://zenodo.org/record/6403931
description: {"references": ["Korneyev, V. A. A revision of Afrotropical species of the Eupyrgota (Diptera, Pyrgotidae): the varipennis and melancholica subgroups of species // Vestnik zoologii. - 2006 b. - 40, N 2. - P. 115 - 130."]}
Connectivity conservation planning through deep reinforcement learning
Creators: name: Equihua, Julián
name: Beckmann, Michael
name: Seppelt, Ralf
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 577

description: The United Nations has declared 2021–2030 the decade on ecosystem restoration with the aim of preventing, stopping and reversing the degradation of the ecosystems of the world, often caused by the fragmentation of natural landscapes. Human activities separate and surround habitats, making them too small to sustain viable animal populations or too far apart to enable foraging and gene flow. Despite the need for strategies to solve fragmentation, it remains unclear how to efficiently reconnect nature. In this paper, we illustrate the potential of deep reinforcement learning (DRL) to tackle the spatial optimisation aspect of connectivity conservation planning. The propensity of spatial optimisation problems to explode in complexity depending on the number of input variables and their states is and will continue to be one of its most serious obstacles. DRL is an emerging class of methods focused on training deep neural networks to solve decision-making tasks and has been used to learn good heuristics for complex optimisation problems. While the potential of DRL to optimise conservation decisions seems huge, only few examples of its application exist. We applied DRL to two real-world raster datasets in a connectivity planning setting, targeting graph-based connectivity indices for optimisation. We show that DRL converges to the known optimums in a small example where the objective is the overall improvement of the Integral Index of Connectivity and the only constraint is the budget. We also show that DRL approximates high-quality solutions on a large example with additional cost and spatial configuration constraints where the more complex Probability of Connectivity Index is targeted. To the best of our knowledge, there is no software that can target this index for optimisation on raster data of this size. DRL can be used to approximate good solutions in complex spatial optimisation problems even when the conservation feature is non-linear like graph-based indices. Furthermore, our methodology decouples the optimisation process and the index calculation, so it can potentially target any other conservation feature implemented in current or future software.
Synthesis reveals approximately balanced biotic differentiation and homogenization
Creators: name: Blowes, Shane A.
name: McGill, Brian J.
name: Brambilla, Viviana
name: Chow, Cher F. Y.
name: Engel, Thore
name: Fontrodona-Eslava, Ada
name: Martins, Inês S.
name: McGlinn, Daniel
name: Moyes, Faye
name: Sagouis, Alban
name: Shimadzu, Hideyasu
name: Van Klink, Roel
name: Xu, Wu-Bing
name: Gotelli, Nicholas J.
name: Magurran, Anne E.
name: Dornelas, Maria
name: Chase, Jonathan
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 570

description: It is commonly thought that the biodiversity crisis includes widespread declines in the spatial variation of species composition, called biotic homogenization. Using a typology relating homogenization and differentiation to local and regional diversity changes, we synthesize patterns across 461 metacommunities surveyed for 10 to 91 years, and 64 species checklists (13 to 500+ years). Across all datasets, we found that no change was the most common outcome, but with many instances of homogenization and differentiation. A weak homogenizing trend of a 0.3% increase in species shared among communities/year on average was driven by increased numbers of widespread (high occupancy) species and strongly associated with checklist data that have longer durations and large spatial scales. At smaller spatial and temporal scales, we show that homogenization and differentiation can be driven by changes in the number and spatial distributions of both rare and common species. The multiscale perspective introduced here can help identify scale-dependent drivers underpinning biotic differentiation and homogenization.
IV: The Tatton Park project, part 3: the post-medieval estate and halls: grandeur to decline
Creators: name: Higham, Nick J
name: Aylett, P
name: Smith, J H
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 76, 81-125
description: Third in a series of reports on the estate (see also 2001/226 and 2001/1099). Notes the importance Lordship played in the later development of the estate. The Egerton family improved and enclosed the land and the farming population was comparatively affluent by contemporary standards. From the 1730s onwards the Egertons progressively emparked Tatton, bring about a gradual shift from an agricultural to a park landscape, although livestock grazing continued. The Egertons constructed the new hall on a green field site and then largely rebuilt it early in the nineteenth century, which is the mansion house that still survives. It was overshadowed by debt until it came into the ownership of the National Trust in the twentieth century.
Adaptive Workload Distribution for Accuracy-aware DNN Inference on Collaborative Edge Platforms
Creators: name: Taufique, Zain
name: Miele, Antonio
name: Liljeberg, Pasi
name: Kanduri, Anil
Publisher: name: arXiv
Year: 2023
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: Performance (cs.PF)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: DNN inference can be accelerated by distributing the workload among a cluster of collaborative edge nodes. Heterogeneity among edge devices and accuracy-performance trade-offs of DNN models present a complex exploration space while catering to the inference performance requirements. In this work, we propose adaptive workload distribution for DNN inference, jointly considering node-level heterogeneity of edge devices, and application-specific accuracy and performance requirements. Our proposed approach combinatorially optimizes heterogeneity-aware workload partitioning and dynamic accuracy configuration of DNN models to ensure performance and accuracy guarantees. We tested our approach on an edge cluster of Odroid XU4, Raspberry Pi4, and Jetson Nano boards and achieved an average gain of 41.52% in performance and 5.2% in output accuracy as compared to state-of-the-art workload distribution strategies.
description: 6 pages, 9 figures, 1 table, 1 algorithm, to be published in 29th Asia and South Pacific Design Automation Conference (IEEE ASP-DAC 2024)
BindingDB Entry 12171: Iminosulfanone compound as bromodomain protein inhibitor and pharmaceutical composition and medical use thereof
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Bromodomain-containing protein 4 [349-460] and Bromodomain-containing protein 4 [44-168], Chia Tai Tianqing Pharmaceutical Group Co., Affinity

description: Small molecule binding data for protein Bromodomain-containing protein 4 [349-460] and Bromodomain-containing protein 4 [44-168], Uniprot O60885
polymers-08-00295.pdf
Creators: name: Nitturi, Naresh Kumar
Publisher: name: figshare
Year: 2016
Subjects: subject: 90301 Biomaterials
subject: FOS: Medical engineering

description: AbstractUltra-high molecular weight polyethylene (UHMWPE) is widely used in artificial joints in the replacement of knee, hip and shoulder that has been impaired as a result of arthritis or other degenerative joint diseases. The UHMWPE made plastic cup is placed in the joint socket in contact with a metal or ceramic ball affixed to a metal stem. Effective reinforcement of multi-walled carbon nanotubes (MWCNTs) in UHMWPE results in improved mechanical and tribological properties. The hydrophobic nature of the nanocomposites surface results in lesser contact with biological fluids during the physiological interaction. In this project, we investigate the UHMWPE/MWCNTs nanocomposites reinforced with MWCNTs at different concentrations. The samples were treated with cold argon plasma at different exposure times. The water contact angles for 60 min plasma-treated nanocomposites with 0.0, 0.5, 1.0, 1.5, and 2.0 wt % MWCNTs were found to be 55.65°, 52.51°, 48.01°, 43.72°, and 37.18° respectively. Increasing the treatment time of nanocomposites has shown transformation from a hydrophobic to a hydrophilic nature due to carboxyl groups being bonded on the surface for treated nanocomposites. Wear analysis was performed under dry, and also under biological lubrication, conditions of all treated samples. The wear factor of untreated pure UHMWPE sample was reduced by 68% and 80%, under dry and lubricated conditions, respectively, as compared to 2 wt % 60 min-treated sample. The kinetic friction co-efficient was also noted under both conditions. The hardness of nanocomposites increased with both MWCNTs loading and plasma treatment time. Similarly, the surface roughness of the nanocomposites was reduced.
DiSSI: GlasWeeAsian evaluation tools
Creators: name: Ross, Kirsty
name: Bhatti, Saeeda
name: Birnie, Ingeborg
name: Essex, Jane
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 390402
subject: Education assessment and evaluation
classificationCode: 390304
subject: Primary education

description: These are the pre- and post-workshop evaluation cards for the GlasWeeAsian Plant Explorers workshop. They are available in multiple languages. They received ethical approval from the University of Strathclyde for anonymous data collection from our workshops. 

How to use the resources

 Print the designs, double sided, onto plain paper or card (no coating) 
 Hand out cards at the start of the workshop, asking the attendees to respond to the prompt question and complete some light demographic information
 Set aside and deliver the workshop
 At the end, ask the attendees to flip over the postcards and complete the reverse side

In theory, you should see an increase in precision, vocabulary, and knowledge after the workshop. We typically get ours printed on A6 or A5 card flyers at our local print shop, rather than using a home printer.

Attribution
Kirsty Ross was responsible for the original text and graphical design of all postcards. Saeeda Bhatti sought out and coordinated other translators and their contributions. The following individuals provided our translations:

 English: Kirsty Ross
 Gaelic: Inge Birnie
High-performance ceramics in musculoskeletal surgery : current use and future perspectives
Creators: name: Eschweiler, Jörg
name: Greven, Johannes
name: Rath, Björn
name: Kobbe, Philipp
name: Modabber, Ali
name: Hildebrand, Frank
name: Migliorini, Filippo
name: Hofmann, Ulf
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Osteoarthritis (OA) is a prevalent disease among the elderly population, necessitating effective treatment options. Total joint arthroplasty (TJA) is a reliable surgical procedure that has shown good long-term clinical outcomes for OA. However, certain challenges, such as implant failure caused by particle-induced aseptic loosening or hypersensitivity to metal ions, remain unresolved in TJA. High-performance ceramic implants have emerged as a promising solution to address these persistent implant-related issues. This review article provides an overview of the composition and characteristics of ceramics used in TJA, highlighting their potential advantages and associated risks. While ceramic implants have demonstrated excellent performance in vivo for hip and knee arthroplasty, their bioinert behaviour is still considered a crucial factor regarding cementless options. Therefore, novel methods are investigated that seem to be able to combine the benefits of ceramic materials with an excellent osseointegration behaviour, which makes ceramics as implant materials an even stronger option for future applications.
Intertwined fractional quantum anomalous Hall states and charge density waves
Creators: name: Song, Xue-Yang
name: Jian, Chao-Ming
name: Fu, Liang
name: Xu, Cenke
Publisher: name: arXiv
Year: 2023
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Motivated by the recent experimental breakthrough on the observation of the fractional quantum anomalous Hall (FQAH) effects in semiconductor and graphene moiré materials, we explore the rich physics associated with the coexistence of FQAH effect and the charge density wave (CDW) order that spontaneously breaks the translation symmetry. We refer to a state with both properties as "FQAH-crystal". We show that the interplay between FQAH effect and CDW can lead to a rich phase diagram including multiple topological phases and topological quantum phase transitions at the same moiré filling. In particular, we demonstrate the possibility of direct quantum phase transitions from a FQAH-crystal with Hall conductivity $σ_H = - 2/3$ to a trivial CDW insulator with $σ_H = 0$, and more interestingly, to a QAH-crystal with $σ_H= -1$.
description: 9 pages
V: New Bridge, new road, new church: the building of Grosvenor Street in Chester
Creators: name: Barnes, G K
Publisher: name: Archaeology Data Service
Year: 2018

description: Journal of the Chester Archaeological Society, 76, 127-151
description: Notes that the nineteenth-century construction of Grosvenor Bridge and Grosvenor Street were the first major disruption to Chester's street plan since the Middle Ages. The paper also examines the process of land acquisition for the construction of the Grosvenor Street and the relocation of St Bridget's Church.