cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Local nanomechanical properties of HeLa-cell surfaces
Creators: name: Gigler, A.
name: Holzwarth, Michael
name: Marti, Othmar
Publisher: name: Universität Ulm
Year: 2007
Subjects: subject: Living cells
subject: DDC 540 / Chemistry & allied sciences
subject: Liquids
subject: Atomic force microscopy
subject: Cell adhesion
subject: Elasticity
subject: Rasterkraftmikroskopie
subject: Adhäsion
subject: Zelladhäsion
subject: Flüssigkeit

description: Using the Digital Pulsed Force Mode (DPFM) approach, the local mechanical properties of living HeLa cells have been examined. The cells were attached to a favorable glass-like substrate. The AFM used for the experiments was a commercial AFM setup by WITec. At every point of the image, approach and retract curves have been performed. The repetition rate of the cycle was 175 Hz. A total of about 500,000 curves has been recorded and completely evaluated for each experiment. The substrate served as an online reference material for calibration purposes. First, the force trajectories were corrected for the viscous drag force in the liquid environment. Second, the curves within the region of the substrate were phase corrected to compensate for the time lag of the signal in the setup assuming a purely elastic response of the reference material. Finally, all the force traces have been corrected by using this information and evaluated according to common continuum-elastic models. The resulting images allow the assignment of values of Young's modulus, local adhesion, hysteretic behavior, etc. at a high lateral resolution all over the cell body. In this paper, we describe the procedure of our measurement and the corresponding signal correction strategy of our automated data evaluation.
Synthesis of long-term temporal trends of targeted soil biodiversity and functions
Creators: name: Sara Del Duca
name: Roberta Pastorelli
name: Marjetka Suhadolc
name: Carmen Trasar-Cepeda
name: Cristina Aponte
name: Markéta Mareckova
name: Stefano Mocali
Publisher: name: Zenodo
Year: 2024

description: The document reports results obtained in the Task 4.3 “Assessment of temporal dynamics of soil biodiversity on chronosequences” Leader: CZU. Participants: CREA (co-leader)
sj-docx-1-chl-10.1177_17475198221131528 – Supplemental material for The design, synthesis, antioxidant, and antihypoxia activities of two new hydroxydaidzein derivatives
Creators: name: Da, Qingyue
name: Shao, Jin
name: Zhang, Pengpeng
name: Zhang, Jie
name: Ma, Huiping
name: Jing, Linlin
Publisher: name: SAGE Journals
Year: 2022
Subjects: Materials Engineering not elsewhere classified

description: Supplemental material, sj-docx-1-chl-10.1177_17475198221131528 for The design, synthesis, antioxidant, and antihypoxia activities of two new hydroxydaidzein derivatives by Qingyue Da, Jin Shao, Pengpeng Zhang, Jie Zhang, Huiping Ma and Linlin Jing in Journal of Chemical Research
Book review: Meandering Sobriety
Creators: name: Le, Ngoc-Thang B.
name: Ho, Manh-Tung
Publisher: name: APU
Year: 2023
Subjects: morality

description: “Meandering Sobriety” by Prof. Vuong Quan Hoang is a thought-provoking narrative that mirrors the process of deep contemplation. Through the author’s collective experiences, readers are invited to reflect on the world around them.
Supplemental Material - The effect of periodate oxidation, tert-butanol treatment, and starch addition in improving melt dispersion of cellulosic fillers in PBAT
Creators: name: Keskes, Mariam
name: Desse, Melinda
name: Jaziri, Mohamed
name: Carrot, Christian
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental Material for The effect of periodate oxidation, tert-Butanol treatment, and starch addition in improving melt dispersion of cellulosic fillers in PBAT by Mariam Keskes, Melinda Desse, Mohamed Jaziri and Christian Carrot in Journal of Thermoplastic Composite Materials
Initial Data Acquisition and Analytics Models : RECAP Deliverable D5.1
Creators: name: Garcia, Rafael
name: Casari, Paolo
name: Domaschka, Jörg
name: Griesinger, Frank
name: Forsman, Johan
name: Area, Carlos
name: Alverez, Lucas
name: Lopez, Miguel Angel
name: Noya, Manuel
name: Parapar, Javier
name: Le Duc, Thang
name: Willis, Peter
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: edge computing
subject: capacity provisioning
subject: monitoring
subject: data analytics
subject: data acquisition
subject: DDC 000 / Computer science, information & general works
subject: Monitoring
subject: Data collection platforms
subject: Computer capacity
subject: Data flow computing
subject: Datenmanagement
subject: Edge computing
subject: Monitoring
subject: Datenanalyse
subject: Datenerhebung
subject: Rechenkapazität

description: Deliverable D5.1 provides a detailed description of the tasks to be performed in the context of RECAP work package WP5, from the point of view of data processing and statistical models. The document also provides an architectural design of the different elements that compose the solution provided by WP5 for data retrieval, management and storage. The document covers both types of data sources: offline (trace-based) and online (monitoring-based). This deliverable covers four critical elements that are required to successfully deliver data analysis for the RECAP project: i) The specific needs of the RECAP use cases in terms of data; ii) The data source(s), transport, transformation and storage; iii) The descriptive analysis and the mathematical models needed in the project; iv) The infrastructure available for querying and visualisation of data; A large portion of the document re-casts and re-interprets the RECAP Use Cases from the point of view of data flow: for each use case, D5.1 describes from where the data is going to be collected, what type of data is available, what kinds of transformation are needed (filtering, aggregation, preprocessing, …), what models are going to be developed, and how the results are going to be visualized. The deliverable provides the foundations, from a data point of view, for the work packages WP6 (workload and application modelling), WP7 (simulation) and WP8 (application placement and infrastructure optimisation). Finally, the document provides valuable information to be used for the architecture and design of RECAP in work package WP4.
sj-docx-1-pie-10.1177_09544089221132988 - Supplemental material for Analysis of the effects of lubricating oil viscosity and engine speed on piston-cylinder liner frictions in a single cylinder HCCI engine by GT-SUITE program
Creators: name: Kunt, M. Akif
name: Calam, Alper
name: Gunes, Haluk
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies
subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, sj-docx-1-pie-10.1177_09544089221132988 for Analysis of the effects of lubricating oil viscosity and engine speed on piston-cylinder liner frictions in a single cylinder HCCI engine by GT-SUITE program by M. Akif Kunt, Alper Calam and Haluk Gunes in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering
title: Der Lehrplan im Kontext eines bildungspolitischen Diskurses
Creators: name: Schmatzberger, Astrid
Year: 2009

description: Die vorliegende Diplomarbeit beschäftigt sich mit der Frage: Spiegeln sich bildungspolitische Diskursinhalte aus den Parlamentsdebatten in dem Lehrplan der Hauptschule wider? Zu Beginn der Arbeit konnte aufgezeigt werden, dass der Entwicklung eines Lehrplans oftmals eine schulpolitische Diskussion vorausgeht. Aus diesem Grund soll in dieser Arbeit erläutert werden, ob die diskutierten Inhalte aus den Sitzungsprotokollen schlussendlich im österreichischen Lehrplan der Hauptschule 1963 wieder zu finden sind. Es konnte keine vergleichbare Studie zu diesem Thema gefunden werden. Zunächst wurde näher auf den Begriff „Lehrplan“ eingegangen und dessen Bedeutung erklärt. Anschließend wurde der Zusammenhang zwischen Lehrplan und der Schulpolitik beleuchtet. Um aufzeigen zu können, ob die diskutierten Inhalte der Bildungspolitik in dem Lehrplan 1963 umgesetzt wurden, wurden Parlamentsdebatten dieser Zeit herangezogen. Aus den Parlamentsdebatten wurden Themen formuliert, die wiederum mit den Lehrplaninhalten verglichen wurden. Die Interpretation der Ergebnisse führte schlussendlich zu Resultaten, die einen Einblick auf den möglichen Einfluss der Politik auf Lehrplaninhalte geben.
description: The present thesis deals with the question: are educational discourse contents from the parliamentary debates reflected in the curriculum of the Austrian Hauptschule? At the beginning of the study could be shown that the development of a school curriculum is often preceded by political discussion. For this reason, in this study is explained whether the contents of the minutes in the curriculum of the Austrian school 1963 are lost. No similar study on this subject could be found. Firstly, the definition of the term “curriculum” was given and its significance explained. Subsequently, the relationship between curriculum and school policy was examined more closely. In order to demonstrate whether the contents of discussion of education policy in the curriculum were implemented in 1963, parliamentary debates are issues which, in turn, were compared with curriculum content. The interpretation of the results ultimately led to results which give an insight on the possible impact of policy on curriculum content.
Epigenetic targeting of Mcl-1 Is synthetically lethal with Bcl-xL/Bcl-2 inhibition in model systems of glioblastoma
Creators: name: Shang, Enyuan
name: Nguyen, Trang T. T.
name: Shu, Chang
name: Westhoff, Mike-Andrew
name: Karpel-Massler, Georg
name: Siegelin, Markus D.
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: THZ1
subject: BH3-mimetics
subject: Mcl1
subject: super-enhancer
subject: non-coding regions
subject: IN-VITRO
subject: CDK7 INHIBITION
subject: CELLS
subject: PROTEIN
subject: CANCER
subject: DDC 610 / Medicine & health
subject: Glioblastoma
subject: Transcription factors
subject: Apoptosis
subject: Epigenome
subject: Gene expression
subject: Krebs
subject: Glioblastom
subject: Apoptosis

description: Apoptotic resistance remains a hallmark of glioblastoma (GBM), the most common primary brain tumor in adults, and a better understanding of this process may result in more efficient treatments. By utilizing chromatin immunoprecipitation with next-generation sequencing (CHIP-seq), we discovered that GBMs harbor a super enhancer around the Mcl-1 locus, a gene that has been known to confer cell death resistance in GBM. We utilized THZ1, a known super-enhancer blocker, and BH3-mimetics, including ABT263, WEHI-539, and ABT199. Combined treatment with BH3-mimetics and THZ1 led to synergistic growth reduction in GBM models. Reduction in cellular viability was accompanied by significant cell death induction with features of apoptosis, including disruption of mitochondrial membrane potential followed by activation of caspases. Mechanistically, THZ1 elicited a profound disruption of the Mcl-1 enhancer region, leading to a sustained suppression of Mcl-1 transcript and protein levels, respectively. Mechanism experiments suggest involvement of Mcl-1 in the cell death elicited by the combination treatment. Finally, the combination treatment of ABT263 and THZ1 resulted in enhanced growth reduction of tumors without induction of detectable toxicity in two patient-derived xenograft models of GBM in vivo. Taken together, these findings suggest that combined epigenetic targeting of Mcl-1 along with Bcl-2/Bcl-xL is potentially therapeutically feasible.
A scalable maximum likelihood method for quantum state tomography
Creators: name: Baumgratz, T.
name: Nuesseler, A.
name: Cramer, M.
name: Plenio, Martin B.
Publisher: name: Universität Ulm
Year: 2013
Subjects: subject: DDC 530 / Physics
subject: Quantum computers
subject: Bayes-Verfahren

description: Abstract The principle of maximum likelihood reconstruction has proven to yield satisfactory results in the context of quantum state tomography for many-body systems of moderate system sizes. Until recently, however, quantum state tomography has been considered to be infeasible for systems consisting of a large number of subsystems due to the exponential growth of the Hilbert space dimension with the number of constituents. Several reconstruction schemes have been proposed since then to overcome the two main obstacles in quantum many-body tomography: experiment time and post-processing resources. Here we discuss one strategy to address these limitations for the maximum likelihood principle by adopting a particular state representation to merge a well established reconstruction algorithm maximizing the likelihood with techniques known from quantum many-body theory.
The Role of Digital History in Cultural Sustainability
Creators: name: International Journal of Indian Science and Research
Publisher: name: International Journal of Indian Science and Research
Year: 2024

description:                                                                                              In an era marked by rapid technological advances, digital history has become increasingly significant in cultural sustainability. This paper explores digital history's impact on preserving and promoting cultural heritage through digitization, accessibility, and community engagement. Despite challenges, digital history enhances cultural revival, cross-cultural dialogue, and economic growth through cultural tourism. This paper underscores the need for collaborative efforts to harness digital history effectively.
Crotalaria gajureliana (Fabaceae: Papilionoideae): a new species from Maharashtra, India with glandular seeds
Creators: name: Gholave, Avinash
name: Madhav, Nilesh
name: Gosavi, Kumar Vinod
name: Kambale, Sharad
Publisher: name: Zenodo
Year: 2021
Subjects: Crotalaria
hyaline glands
Maharashtra
section-Calycinae
subsection Diffusae

description: The new species Crotalaria gajureliana is described and illustrated. It was found in the Nashik district, Maharashtra state, India. Crotalaria gajureliana is a member of C. sect.
 Calycinae subsect. Diffusae and it is closely related to C. filipes. However, the presenceof hyaline, irregularly shaped glands throughout the seeds makes it unique within the
 genus. A key to the species of C. subsect. Diffusae in India is provided to facilitate identification.
description: The plant material was collected from Nashik district and novelty was confirmed by using regional floras, mannual and consulting type specimens and protologue of its related species i. e. Crotalaria filipes. The nomeclature of new species has been made by following the ICN rules. The type specimens of new species i. e. Crotalaria gajureliana will be diposited in mentioned herbaria after publication.
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 262 (33. Jg.), Juni 2003
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Uni Ulm intern
subject: Universities; Germany; Ulm
subject: Ulm / Universität

description: N/A
title: Über die Zusammenarbeit mit den Eltern in der Frühförderung hörbeeinträchtigter Kinder
Creators: name: Kluger, Ingrid
Year: 2009

description: Vor mehr als 30 Jahren begann die „institutionalisierte Frühförderung“ behinderter Kinder. Von Anfang an wurde in diesem Arbeitsfeld die Zusammenarbeit mit den Eltern als ein integraler Bestandteil gesehen. Das Studium der Fachliteratur zu diesem Thema lässt die Feststellung zu, dass es immer wieder Diskussionen darüber gab und gibt, wie diese Zusammenarbeit aussehen kann und soll. Ein wichtiger Anstoß für die Abkehr vom „Ko-Therapeutenmodell“ und für die Entwicklung eines „Kooperationsmodells“ war der „Brief einer Mutter“ von Hanni Holthaus (1983). Ihre sehr klar auf den Punkt gebrachte Kritik ist Grundlage dieser Arbeit und daraus wurden zwei Forschungsfragen abgeleitet: Sind die von Holthaus 1983 geäußerten Kritikpunkte auch in aktuellen Elternberichten über die Frühförderung ihrer hörbeeinträchtigten Kinder zu finden? Welche Frühfördermaßnahmen wurden von den Eltern in ihren Beiträgen als hilfreich, positiv und entlastend beschrieben? Zur Beantwortung der beiden Fragen wurde die Methode der qualitativen Inhaltsanalyse gewählt. Erfahrungsberichte von Eltern hörgeschädigter Kinder aus Fachzeitschriften der Jahrgänge 1996-2006 sowie aus einigen Sammelbänden wurden auf Aussagen zur Frühförderung hin untersucht. Diese Aussagen wurden einem Transformationsprozess unterzogen, um sie danach bestimmten Kategorien zuordnen zu können, welche zur Beantwortung der beiden Forschungsfragen erstellt wurden. In den Erfahrungsberichten von Eltern hörgeschädigter Kinder konnten Aussagen gefunden werden, die sich zum Teil mit jenen von Holthaus decken. In Bezug auf die Beantwortung der zweiten Forschungsfrage kann festgestellt werden, dass sich die Zusammenarbeit mit den Eltern positiv verändert hat. Die von Experten in der Fachliteratur geforderte Kooperation und der partnerschaftliche Umgang wurden umgesetzt und von den Eltern als große Hilfe und Entlastung empfunden.
sj-doc-1-cpx-10.1177_21677026231170839 – Supplemental material for Stress Accumulation, Depressive Symptoms, and Sleep Problems Among Black Americans in the Rural South
Creators: name: Adesogan, Olutosin
name: Lavner, Justin A.
name: Carter, Sierra E.
name: Beach, Steven R. H.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-doc-1-cpx-10.1177_21677026231170839 for Stress Accumulation, Depressive Symptoms, and Sleep Problems Among Black Americans in the Rural South by Olutosin Adesogan, Justin A. Lavner, Sierra E. Carter and Steven R. H. Beach in Clinical Psychological Science
Optimal sequence similarity thresholds for clustering of molecular operational taxonomic units in DNA metabarcoding studies
Creators: name: Bonin, Aurélie
name: Guerrieri, Alessia
name: Ficetola, Gentile F.
Publisher: name: Zenodo
Year: 2022

description: Clustering approaches are pivotal to handle the many sequence variants obtained in DNA metabarcoding datasets, therefore they have become a key step of metabarcoding analysis pipelines. Clustering often relies on a sequence similarity threshold to gather sequences in Molecular Operational Taxonomic Units (MOTUs), each of which ideally representing a homogeneous taxonomic entity, e.g. a species or a genus. However, the choice of the clustering threshold is rarely justified, and its impact on MOTU over-splitting or over-merging even less tested. Here, we evaluated clustering threshold values for several metabarcoding markers under different criteria: limitation of MOTU over-merging, limitation of MOTU over-splitting, and trade-off between over-merging and over-splitting. We extracted sequences from a public database for nine markers, ranging from generalist markers targeting Bacteria or Eukaryota, to more specific markers targeting a class or a subclass (e.g. Insecta, Oligochaeta). Based on the distributions of pairwise sequence similarities within species and within genera, and on the rates of over-splitting and over-merging across different clustering thresholds, we were able to propose threshold values minimizing the risk of over-splitting, that of over-merging, or offering a trade-off between the two risks. For generalist markers, high similarity thresholds (0.96-0.99) are generally appropriate, while more specific markers require lower values (0.85-0.96). These results do not support the use of a fixed clustering threshold. Instead, we advocate a careful examination of the most appropriate threshold based on the research objectives, the potential costs of over-splitting and over-merging, and the features of the studied markers.
description: Funding provided by: European Research Council
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100000781
Award Number: 772284
Jenseits von Ladungsausgleich: Gegenkationen in der Polyoxometallat‐Chemie
Creators: name: Misra, Archismita
name: Kozma, Karoly
name: Streb, Carsten
name: Nyman, May
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Kationen
subject: Komposite
subject: Wechselwirkungen
subject: DDC 540 / Chemistry & allied sciences
subject: Cations
subject: Supramolecular chemistry
subject: Kation
subject: Polyoxometallate
subject: Supramolekulare Chemie
subject: Wechselwirkung

description: Polyoxometallate (POMs) sind molekulare Metalloxidanionen, die Anwendung in Energiewandlung und -speicherung, biomolekularer Chemie sowie Materialdesign und -integration finden. Das Wechselspiel von intrinsisch anionischen POMs mit organischen oder anorganischen Gegenionen wird häufig übersehen, ist jedoch essenziell, um die Aggregation, Stabilisierung, Löslichkeit und Funktion von POMs zu verstehen. Jenseits von einfachen Alkalimetall- oder Ammoniumkationen können neuartige Anwendungen durch vielseitige Kationen wie Dendrimere, mehrwertige Metallkationen, Metallkomplexe, Amphiphile oder Alkaloidkationen erzielt werden. Dieser Aufsatz gibt einen Überblick über grundlegende POM-Kation-Wechselwirkungen in Lösung, die daraus resultierenden Festkörperstrukturen und bespricht neuartige Reaktivitäten und Eigenschaften, die aus diesen Wechselwrkungen resultieren. Wir untersuchen, wie anwendungsnahe Forschung das Kation-kontrollierte Design neuartiger POM-Materialien ermöglicht hat, was wiederum den Wunsch nach der Aufklärung der Grundlagen von POM-Kation-Wechselwirkungen angeregt hat.
sj-doc-1-ict-10.1177_15347354231172511 – Supplemental material for Effects of Managing Cancer and Living Meaningfully on Cancer-Related Fatigue and Cytokine Levels in Gastrointestinal Cancer Patients
Creators: name: Cai, Yinlian
name: Zhang, Qianqian
name: Gan, Chen
name: Xu, Jian
name: Yu, Sheng
name: Tang, Lingxue
name: Yao, Senbang
name: Li, Wen
name: Huang, Runze
name: Cheng, Huaidong
Publisher: name: SAGE Journals
Year: 2023
Subjects: Health and Community Services
Endocrinology
Oncology and Carcinogenesis not elsewhere classified
Aged Health Care

description: Supplemental material, sj-doc-1-ict-10.1177_15347354231172511 for Effects of Managing Cancer and Living Meaningfully on Cancer-Related Fatigue and Cytokine Levels in Gastrointestinal Cancer Patients by Yinlian Cai, Qianqian Zhang, Chen Gan, Jian Xu, Sheng Yu, Lingxue Tang, Senbang Yao, Wen Li, Runze Huang and Huaidong Cheng in Integrative Cancer Therapies
Direct observation of swap cooling in atom–ion collisions
Creators: name: Mahdian, Amir
name: Krükow, Artjom
name: Hecker Denschlag, Johannes
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Swap cooling
subject: Atom–ion collision
subject: DDC 530 / Physics
subject: Ion-atom collisions
subject: Charge exchange
subject: Ladungstransfer

description: Collisions with cold particles can dissipate a hot particle’s energy and therefore can be exploited as a cooling mechanism. Kinetics teach us that cooling a particle down by several orders of magnitude typically takes many elastic collisions as each one only carries away a fraction of the collision energy. Recently, for a system comprising hot ions and cold atoms, a very fast cooling process has been suggested (Ravi et al 2012 Nat. Commun. 3 1126) where cooling over several orders of magnitude can occur in a single step. Namely, in a homo-nuclear atom–ion collision, an electron can resonantly hop from an ultracold atom onto the hot ion, converting the cold atom into a cold ion. Here, we demonstrate such swap cooling in a direct way as we experimentally observe how a single energetic ion loses energy in a cold atom cloud. In order to contrast swap cooling with sympathetic cooling, we perform the same measurements with a hetero-nuclear atom–ion system, for which swap cooling cannot take place, and indeed observe very different cooling dynamics. Ab initio numerical model calculations agree well with our measured data and corroborate our interpretations.
Hábitos de Consumo de redes sociales en los jóvenes | UTP | FISC
Creators: name: 2IL111 - FISC - UTP
Publisher: name: Zenodo
Year: 2024
Subjects: Social Media
Local
University Study
Polling

description: Este estudio examina los patrones de uso de redes sociales entre estudiantes universitarios de la Facultad de Sistemas, analizando frecuencia de uso, preferencias de contenido, dispositivos utilizados y diferencias por género. La investigación se basa en una muestra de 76 estudiantes, proporcionando una visión detallada de los hábitos digitales en el contexto académico actual.
sj-docx-1-aut-10.1177_13623613231177776 – Supplemental material for The effect of autistic traits on prosocial behavior: The chain mediating role of received social support and perceived social support
Creators: name: Zhang, Shuhua
name: Li, Hong
name: Li, Hai
name: Zhao, Shuo
Publisher: name: SAGE Journals
Year: 2023
Subjects: Psychology not elsewhere classified
Psychiatry (incl. Psychotherapy)
Public Health and Health Services not elsewhere classified
Education
Special Education and Disability

description: Supplemental material, sj-docx-1-aut-10.1177_13623613231177776 for The effect of autistic traits on prosocial behavior: The chain mediating role of received social support and perceived social support by Shuhua Zhang, Hong Li, Hai Li and Shuo Zhao in Autism
ZEFI-PTR-G-ThermalChallenge
Creators: name: Lipshutz, Sara
name: Howell, Clara
name: Buechlein, Aaron
name: Douglas, Rusch
name: Rosvall, Kimberly
name: Derryberry, Elizabeth
Publisher: name: Zenodo
Year: 2022
Subjects: thermal stress
zebra finch
Taeniopygia guttata
transcriptomics
environmental change

description: In a rapidly warming world, exposure to high temperatures may impact fitness, but the gene regulatory mechanisms that link sublethal heat to sexually selected traits are not well understood, particularly in endothermic animals. Our experiment used zebra finches (Taeniopygia guttata), songbirds that experience extreme temperature fluctuations in their native Australia. We exposed captive males to an acute thermal challenge (43°C) compared with thermoneutral (35°C) and lower (27°C) temperatures. We found significantly more heat dissipation behaviors at 43°C, a temperature previously shown to reduce song production and fertility, and more heat retention behaviors at 27°C. Next, we characterized transcriptomic responses in tissues important for mating effort – the posterior telencephalon, for its role in song production, and the testis, for its role in fertility and hormone production. Differential expression of hundreds of genes in the testes, but few in the brain, suggest the brain is less responsive to extreme temperatures. Nevertheless, gene network analyses revealed that expression related to dopaminergic signaling in the brain co-varied with heat dissipation behaviors, providing a mechanism by which temporary thermal challenges may alter motivational circuits for song production. In both brain and testis, we also observed correlations between thermally sensitive gene networks and individual differences in thermoregulatory behavior. Although we cannot directly relate these gene regulatory changes to mating success, our results suggest that individual variation in response to thermal challenges could impact sexually selected traits in a warming world.
description: Please see ReadMe fileFunding provided by: National Science Foundation
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000001
Award Number: DBI-1907134Funding provided by: National Science Foundation
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000001
Award Number: IOS-2032412
description: Two tissues (posterior telencephalon and testis) were collected from 24 male zebra finches exposed to temperatures above (Ta = 43°C), within (Ta = 35°C), or below their thermoneutral zone (Ta = 27°C); total RNA was extracted and run on a Nextseq platform.
title: Schmerzerfassung in der Geriatrie
Creators: name: Höller, Nadine
Year: 2009

description: Diese Arbeit stellt die Herausforderung bei der Schmerzerfassung bei geriatrieschen Patienten und Patientinnen dar. Sie zeigt weiters Möglichkeiten auf Schmerzen bei nicht verbalen und dementen Patienten und Patientinnen zu erfassen.
T cell specific BOB.1/OBF.1 expression promotes germinal center response and T helper cell differentiation
Creators: name: Betzler, Annika C.
name: Ezić, Jasmin
name: Kors, Tsima Abou
name: Hoffmann, Thomas K.
name: Wirth, Thomas
name: Brunner, Cornelia
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: BOB.1/OBF.1
subject: T cell differentiation
subject: Follicular T helper cells
subject: Transcriptional co-activator
subject: Pou2af1
subject: DDC 610 / Medicine & health
subject: T-Lymphocytes, Helper-inducer
subject: Immunity, Humoral
subject: Germinal center
subject: Transcription, Genetic
subject: Trans-activators
subject: T-Lymphozyt
subject: Helferzelle
subject: Humorale Immunität
subject: Transkription

description: The transcriptional co-activator BOB.1/OBF.1 is expressed in both B and T cells. The main characteristic of conventional BOB.1/OBF.1 deficient mice is the complete absence of germinal centers (GCs). This defect was mainly attributed to the defective B cell compartment. However, it is unknown whether and how BOB.1/OBF.1 expression in T cells contributes to the GC reaction. To finally clarify this question, we studied the in vivo function of BOB.1/OBF.1 in CD4+ T and follicular T helper (TFH) cell subpopulations by conditional mutagenesis, in the presence of immunocompetent B lymphocytes. BOB.1/OBF.1 deletion in CD4+ T as well as TFH cells resulted in impaired GC formation demonstrating that the impaired GC reaction described for conventional BOB.1/OBF.1-deficient mice cannot exclusively be traced back to the B cell compartment. Furthermore, we show a requirement of BOB.1/OBF.1 for T helper (TH) cell subsets, particularly for TFH cell differentiation.
Acyl and decarbonylative cross-coupling of carboxylic acid derivatives and sterically-defined, biaryl L-shaped NHC (NHC = N-heterocyclic carbene) ligands for metal catalysis
Creators: name: Zhou, Tongliang
Publisher: name: No Publisher Supplied
Year: 2023

description: The amide bond is one of the most crucial functional motifs in both chemistry and biology. Despite its vital role as a ubiquitous pharmacophore in medicinal chemistry and its stability as an intermediate in organic synthesis, transition-metal-catalyzed transformations involving acyl N–C bond activation of amides have remained largely unexplored. The considerable activation energy required for N–C(O) bond cleavage, attributed to the resonance of amide bond (resonance energy of 15-20 kcal/mol), poses a significant challenge for selective metal insertion into the N–C(O) bond. In 2015, the concept of activating amide bonds through ground-state destabilization was proposed by our group. In this general approach, the resonance of amides is tailored through steric and electronic substitution, thus enabling synthetically-useful metal insertion into the N–C(O) bond. Based on this concept, numerous transition-metal-catalyzed transformations employing amides as electrophiles have been reported.On the other hand, the isolation of free N-heterocyclic carbenes (NHCs) and the use of N-heterocyclic carbenes in catalysis marked the emergence of a novel class of ligands for organic synthesis. Starting as laboratory curiosities, N-heterocyclic carbenes have now evolved into exceptionally powerful tools in homogeneous catalysis, finding numerous applications in valuable synthetic transformations.The first part of this thesis describes the development of acyl and decarbonylative cross-coupling of amides and related carboxylic acid derivatives through selective acyl cleavage. This part includes: (1) the development of [Pd(IPr)(acac)Cl] as a highly reactive precatalyst for the acyl Suzuki-Miyaura and Buchwald-Hartwig cross-coupling of amides; (2) the development of the first palladium-catalyzed decarbonylative Suzuki-Miyaura cross-coupling of amides, furnishing significantly broader substrate scope and functional group tolerance than nickel catalysis; (3) the development of the first palladium-catalyzed decarbonylative Suzuki-Miyaura cross-coupling of common aroyl chlorides; (4) the establishment of NHC–Pd(II) chloro dimers with the general structure of [Pd(NHC)(-Cl)Cl]2 as the most reactive Pd(II)–NHC catalysts developed to date.The second part of this thesis describes the development of sterically-defined biaryl L-shaped ImPy (ImPy = imidazo[1,5-a]pyridin-3-ylidene) ligands as a novel technology for the advancement of new catalytic reactions. This part includes: (1) the development of highly reactive, well-defined Pd(II)–ImPy complexes for the Suzuki-Miyaura cross-coupling of nitroarenes; (2) the development of late-stage hydrazination of aryl halides using sterically demanding biaryl L-shaped ImPy ligands; (3) the development of gold-catalyzed reductive hydroamination of alkynes (RHAA) with nitroarenes for amine synthesis via Au–H/Au+/Au–H triple relay catalysis.
Salt, Gandhi & British Raj:  Special Reference to 1930
Creators: name: International Journal of Indian Science and Research
Publisher: name: International Journal of Indian Science and Research
Year: 2024

description:            Salt is a commodity that had been taxed in India since the time of the Mauryas period. Taxes on salt have been common even during the time of Chandragupta Maurya. The Arthashastra, which give an account of the different duties of the people, says that a special officer called lavananadhyaksa was appointed to collect the salt tax.1 Taxes were also forced on imported salt. However, they accounted for 25 percent of the total cost of the salt.
The volume of a sugar loaf
Creators: name: Kreiner, Welf A.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Archimedes
subject: Parabola
subject: Rotational body
subject: Sugar loaf
subject: Surface line
subject: DDC 500 / Natural sciences & mathematics
subject: Archimedes
subject: Parabola
subject: Parabel (Mathematik)

description: The shape of a geometrical body is described its volume being half of that of a circumscribed cylinder and larger than an inscribed cone. It is rotationally symmetrical and its shape reminds to a sugar loaf. While the contour of a cone jacket is a straight line, the contour of the sugar loaf follows a line similar to a parabola, just with an exponent slightly below 2. The value used here is 1.780 776 41.
Additional file 1 of Reintroducing face-to-face support alongside remote support to form a hybrid stop smoking service in England: a formative mixed methods evaluation
Creators: name: Woodrow, Nicholas
name: Gillespie, Duncan
name: Kitchin, Liz
name: O’Brien, Mark
name: Chapman, Scott
name: Chng, Nai Rui
name: Passey, Andrew
name: Aquino, Maria Raisa Jessica
name: Clarke, Zoe
name: Goyder, Elizabeth
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Supplementary Material 1
sj-docx-1-tag-10.1177_17562848231174953 – Supplemental material for Long-term outcomes of vedolizumab in inflammatory bowel disease: the Swedish prospective multicentre SVEAH extension study
Creators: name: Visuri, Isabella
name: Eriksson, Carl
name: Karlqvist, Sara
name: Lykiardopoulos, Byron
name: Karlén, Per
name: Grip, Olof
name: Söderman, Charlotte
name: Almer, Sven
name: Hertervig, Erik
name: Marsal, Jan
name: Malmgren, Carolina
name: Delin, Jenny
name: Strid, Hans
name: Sjöberg, Mats
name: Bergemalm, Daniel
name: Hjortswang, Henrik
name: Halfvarson, Jonas
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: FOS: Health sciences
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-1-tag-10.1177_17562848231174953 for Long-term outcomes of vedolizumab in inflammatory bowel disease: the Swedish prospective multicentre SVEAH extension study by Isabella Visuri, Carl Eriksson, Sara Karlqvist, Byron Lykiardopoulos, Per Karlén, Olof Grip, Charlotte Söderman, Sven Almer, Erik Hertervig, Jan Marsal, Carolina Malmgren, Jenny Delin, Hans Strid, Mats Sjöberg, Daniel Bergemalm, Henrik Hjortswang and Jonas Halfvarson in Therapeutic Advances in Gastroenterology
Copper-templated formation of dihelical oligothiophene-phenanthroline assemblies
Creators: name: Schmid, Sylvia
name: Wunderlin, Markus
name: Mena-Osteritz, Elena
name: Bäuerle, Peter
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Helicates
subject: Copper(I) com- plexation
subject: DDC 540 / Chemistry & allied sciences
subject: Oligothiophenes
subject: Phenanthrolines
subject: Oligothiophene
subject: Phenanthroline
subject: Helicate

description: We report the synthesis and comprehensive characterization of a series of (oligo)thiophene-bridged (bis)phenanthroline ligands. The complexation behavior of the ditopic ligands with Cu(I) was explored by high-resolution ESI mass spectrometry, UV‑vis spectroscopy, and elec- trochemistry. Whereas ligands, in which the phenanthrolines are bridged by smaller (oligo)thiophene units, provided mainly mononu- clear complexes, quaterthiophene-based ditopic ligands show a strong tendency to undergo metal-templated self-assembly into double- stranded, dinuclear helicates.
Movement, translocation and MRR data for Heliconius butterflies
Creators: name: Moura, Priscila A.
name: Corso, Gilberto
name: Montgomery, Stephen H.
name: Cardoso, Márcio Z.
Publisher: name: Zenodo
Year: 2021
Subjects: Heliconius
Heliconius erato
Heliconius melpomene
mark-release-recapture
Translocation experiment
movement behavior

description: Site fidelity plays an important role in increasing foraging efficiency, particularly when food resources are reliable. In insects, site fidelity has largely been studied in Hymenopteran species, which consistently return to their nest site after foraging bouts. In butterflies, evidence of foraging site fidelity are limited but may be present in species with specific foraging specialisations, such as Heliconius, which have a derived foraging behaviour centred around active pollen feeding. Unlike many Hymenoptera, Heliconius are neither eusocial nor nesting species, positioning them as a peculiar case where foraging site fidelity may occur in the absence of any central nest-like structure. However, to date, existing studies do not consider low dispersal as an alternative to site fidelity. In this study, we use a mark-release-recapture experiment to test whether individuals of two Heliconius species exhibit true site fidelity. We further test this fidelity by measuring flight orientation during a translocation experiment, and by recapturing translocated butterflies to identify whether individuals return to their site of origin. We found that non-translocated butterflies display extreme stability in site choice, and translocated butterflies consistently return to their site of origin, rapidly orientating towards their home site upon release. This suggests site fidelity in Heliconius is not solely explained by low dispersal, but is a response to the distribution and stability in ecological resources. We further note that the ability to return to home sites when artificially dispersed suggests a sophisticated ability to navigate to specific spatial goals. Our study provides insights into the ecological drivers of site fidelity, a novel example distinct from nest building or group living, and opens an avenue of new research on navigational mechanisms in insects.
title: Was ist Stil?
Creators: name: Schild, Michael
Year: 2009

description: In der vorliegende Arbeit wird der Versuch unternommen aufschlussreiche Erkenntnisse über stilistische Aspekte von Kunstwerken zu gewinnen. Dabei werden verschiedene Gemälde hinsichtlich charakteristischer Merkmale gezielt manipuliert. Anschliessend wird in einem psychophysischen Versuchsdesign untersucht wie sich diese Manipulationen auf den Wahrnehmungsprozess der Versuchspersonen auswirken.
description: With this paper the author tries to find useful information regarding stylistic aspects of art. Different paintings are manipulated concerning characteristic properties that might be important for perceiving art. Subsequently consequences in the viewers perceptional process are analysed in a psychophysical experimental design.
sj-docx-3-tag-10.1177_17562848231174953 – Supplemental material for Long-term outcomes of vedolizumab in inflammatory bowel disease: the Swedish prospective multicentre SVEAH extension study
Creators: name: Visuri, Isabella
name: Eriksson, Carl
name: Karlqvist, Sara
name: Lykiardopoulos, Byron
name: Karlén, Per
name: Grip, Olof
name: Söderman, Charlotte
name: Almer, Sven
name: Hertervig, Erik
name: Marsal, Jan
name: Malmgren, Carolina
name: Delin, Jenny
name: Strid, Hans
name: Sjöberg, Mats
name: Bergemalm, Daniel
name: Hjortswang, Henrik
name: Halfvarson, Jonas
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: FOS: Health sciences
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-3-tag-10.1177_17562848231174953 for Long-term outcomes of vedolizumab in inflammatory bowel disease: the Swedish prospective multicentre SVEAH extension study by Isabella Visuri, Carl Eriksson, Sara Karlqvist, Byron Lykiardopoulos, Per Karlén, Olof Grip, Charlotte Söderman, Sven Almer, Erik Hertervig, Jan Marsal, Carolina Malmgren, Jenny Delin, Hans Strid, Mats Sjöberg, Daniel Bergemalm, Henrik Hjortswang and Jonas Halfvarson in Therapeutic Advances in Gastroenterology
Additional file 2 of Reintroducing face-to-face support alongside remote support to form a hybrid stop smoking service in England: a formative mixed methods evaluation
Creators: name: Woodrow, Nicholas
name: Gillespie, Duncan
name: Kitchin, Liz
name: O’Brien, Mark
name: Chapman, Scott
name: Chng, Nai Rui
name: Passey, Andrew
name: Aquino, Maria Raisa Jessica
name: Clarke, Zoe
name: Goyder, Elizabeth
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Supplementary Material 2
Journey into "Meandering Sobriety": An Enigmatic Literary Creation
Creators: name: Duong, Minh-Phuong Thi
Publisher: name: TDTU
Year: 2023
Subjects: literary masterpiece

description: In the modern world, filled with information overload and constant distractions, Professor Vuong Quan Hoang’s “Meandering Sobriety” stands as a literary masterpiece that prompts deep introspection.
sj-docx-1-soe-10.1177_00380407231210279 – Supplemental material for Trends and Determinants of Intergenerational Educational Inequality in Sub-Saharan Africa for Birth Cohorts 1974 to 2003
Creators: name: Plavgo, Ilze
name: Bernardi, Fabrizio
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Education
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-1-soe-10.1177_00380407231210279 for Trends and Determinants of Intergenerational Educational Inequality in Sub-Saharan Africa for Birth Cohorts 1974 to 2003 by Ilze Plavgo and Fabrizio Bernardi in Sociology of Education
Mining digital traces of facebook activity for the prediction of individual differences in tendencies toward social networks use disorder: a machine learning approach
Creators: name: Marengo, Davide
name: Montag, Christian
name: Mignogna, Alessandro
name: Settanni, Michele
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: digital footprints
subject: digital phenotyping
subject: problematic social media use
subject: social networks use disorder
subject: behavioral addictions
subject: DDC 150 / Psychology
subject: DDC 300 / Social sciences
subject: Data mining
subject: Social Media

description: More than three billion users are currently on one of Meta’s online platforms with Facebook being still their most prominent social media service. It is well known that Facebook has designed a highly immersive social media service with the aim to prolong online time of its users, as this results in more digital footprints to be studied and monetized (via psychological targeting). In this context, it is debated if social media platforms can elicit addictive behaviors. In the present work, we demonstrate in N = 1,094 users that it is possible to predict from digital footprints of the Facebook users their self-reported addictive tendencies toward social media (R > 0.30) by applying machine-learning strategies. More specifically, we analyzed the predictive power of a set of models based on different sets of features extracted from digital traces, namely posting activity, language use, and page Likes. To maximize the predictive power of the models, we used an ensemble of linear and non-linear prediction algorithms. This work showed also sufficient accuracy rates (AUC above 0.70) in distinguishing between disordered and non-disordered social media users. In sum, individual differences in tendencies toward “social networks use disorder” can be inferred from digital traces left on the social media platform Facebook. Please note that the present work is limited by its cross-sectional design.
Additional file 3 of Reintroducing face-to-face support alongside remote support to form a hybrid stop smoking service in England: a formative mixed methods evaluation
Creators: name: Woodrow, Nicholas
name: Gillespie, Duncan
name: Kitchin, Liz
name: O’Brien, Mark
name: Chapman, Scott
name: Chng, Nai Rui
name: Passey, Andrew
name: Aquino, Maria Raisa Jessica
name: Clarke, Zoe
name: Goyder, Elizabeth
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Supplementary Material 3
Supplementary Information for "Performance evaluation of adaptive introgression classification methods"
Creators: name: Romieu, Jules
name: Camarata, Ghislain
name: André-Crochet, Pierre
name: de Navascués, Miguel
name: Leblois, Raphaël
name: Rousset, Francois
Publisher: name: Zenodo
Year: 2024

description: Supplementary information : supplementary figures and tables from "Performance evaluation of adaptive introgression classification methods".  ROC curves and score value by non-AI windows type for various demographic scenarios.