cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture
Creators: name: Zeisel, S.H.
name: Albright, C.D.
name: Salganik, R.I.
name: Bethea, T.C.
name: Liu, R.
name: Da Costa, K.-A.
Publisher: name: FASEB
Year: 1996

description: Immortalized CWSV-1 rat hepatocytes, in which p53 protein is inactivated by SV40 large T antigen, had increased numbers of cells with strand breaks in genomic DNA (terminal dUTP end labeling) when grown in 0 μM choline (67-73% of cells) than when grown in 70 μM choline (2-3% of cells). Internucleosomal fragmentation of DNA (DNA ladders) was detected in cells grown with 5 μM and 0 μM choline for 72 h. Cells treated with 0 or 5 μM choline for 72 h detached from the substrate in high numbers (58% of choline deficient cells vs. 1.4% of choline sufficient cells detached) exhibited a high incidence of apoptosis (apoptotic bodies were seen in 55-75% of cells; 67-73% had DNA strand breaks), and an absence of mitosis and proliferating cell nuclear antigen (PCNA) expression. Cells undergoing DNA fragmentation had functioning mitochondria. At 24 h, cells grown in 0 or 5 μM choline synthesized DNA more rapidly than those grownin 70 μM choline. By 72 h, the cells grown in 0 or 5 μM choline were forming DNA much more slowly than control cells (assessed by thymidine incorporation, PCNA expression, and mitotic index). Western blot analysis showed that p53 in the nucleus of cells was detected in direct association with SV40 T-antigen, and was therefore likely to be inactive. We conclude that choline deficiency kills CWSV-1 hepatocytes in culture by inducing apoptosis via what may be a p53-independent process, and that this process begins in viable cells before they detach from the culture dish.
Rossby waves and eddy-mean flow interaction in the shallow-water system
Creators: name: Haigh, Michael Christopher
Publisher: name: Imperial College London
Year: 2019

description: The primary aim of this thesis is to understand the dynamics of oceanic mesoscale eddies induced by a localised ‘plunger’ forcing in the rotating shallow-water model. Intended to be an elementary representation of transient eddy forcing in the ocean, the properties of this forcing are motivated by three-layer shallow-water double-gyre dynamics. The forcing is imposed on a zonal background flow and we consider the linear flow response and its ‘quasi-nonlinear’ self-interaction. Aside from the aim of developing the theory of shallow-water Rossby waves, we are motivated by the need to be prepared for the development of stochastic parameterisations of oceanic mesoscale eddies. The plunger forcing induces a rich spectrum of Rossby waves that redistribute potential vorticity (PV) and zonal momentum, the properties of which have a strong and significant dependence on the background flow. For a uniform background flow, the plunger drives northward PV flux convergence, equivalent to a convergence of zonal momentum fluxes at the forced latitudes. This is due to outward meridional propagation of Rossby waves which transport westward momentum away from their source. The amplitude of the PV/zonal momentum redistribution has a robust dependence on the direction and speed of the background flow, with, for example, maximal net- northward PV flux convergence for a weak westward background flow. The amplitude of PV/zonal momentum redistribution can be attributed to two factors: (1) resonance between the plunger and the available Rossby wave spectrum, and (2) efficiency of nonlinear self-interaction. For a Gaussian-jet background flow the flow response and quasi-nonlinear self-interaction are more complicated due to the non-trivial background PV gradient. In this case we concentrate on the role of plunger latitude, and show that results can be explained by considering Rossby wave refractive index theory, critical layers and turning latitudes.
Choline phospholipids: Signal transduction and carcinogenesis
Creators: name: Zeisel, S.H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Phospholipids act as vital elements in transmembrane signaling. Agonist- induced hydrolysis of phosphatidylinositides has been established as a major mechanism for transmitting messages into the interior of cells via protein phosphorylation cascades, ultimately regulating gene transcription. There is a growing body of evidence that choline phospholipids (phosphatidylcholine, sphingomyelin, and their metabolites) also are important mediators and modulators of transmembrane signaling. These functions may explain how choline phospholipids influence normal physiological processes as well as a diverse group of pathological processes.
(502210) Jane Bell
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Intra-cavity gain shaping of mode-locked Ti:Sapphire laser oscillations
Creators: name: Yefet, Shai
name: Amer, Na'aman
name: Pe'er, Avi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The gain properties of an oscillator strongly affect its behavior. When the gain is homogeneous, different modes compete for gain resources in a `winner takes all' manner, whereas with inhomogeneous gain, modes can coexist if they utilize different gain resources. We demonstrate precise control over the mode competition in a mode locked Ti:sapphire oscillator by manipulation and spectral shaping of the gain properties, thus steering the competition towards a desired, otherwise inaccessible, oscillation. Specifically, by adding a small amount of spectrally shaped inhomogeneous gain to the standard homogeneous gain oscillator, we selectively enhance a desired two-color oscillation, which is inherently unstable to mode competition and could not exist in a purely homogeneous gain oscillator. By tuning the parameters of the additional inhomogeneous gain we flexibly control the center wavelengths, relative intensities and widths of the two colors.
Robust multimodal dense SLAM
Creators: name: Laidlow, Tristan William
Publisher: name: Imperial College London
Year: 2019

description: To enable increasingly intelligent behaviours, autonomous robots will need to be equipped with a deep understanding of their surrounding environment. It would be particularly desirable if this level of perception could be achieved automatically through the use of vision-based sensing, as passive cameras make a compelling sensor choice for robotic platforms due to their low cost, low weight, and low power consumption. Fundamental to extracting a high-level understanding from a set of 2D images is an understanding of the underlying 3D geometry of the environment. In mobile robotics, the most popular and successful technique for building a representation of 3D geometry from 2D images is Visual Simultaneous Localisation and Mapping (SLAM). While sparse, landmark-based SLAM systems have demonstrated high levels of accuracy and robustness, they are only capable of producing sparse maps. In general, to move beyond simple navigation to scene understanding and interaction, dense 3D reconstructions are required. Dense SLAM systems naturally allow for online dense scene reconstruction, but suffer from a lack of robustness due to the fact that the dense image alignment used in the tracking step has a narrow convergence basin and that the photometric-based depth estimation used in the mapping step is typically poorly constrained due to the presence of occlusions and homogeneous textures. This thesis develops methods that can be used to increase the robustness of dense SLAM by fusing additional sensing modalities into standard dense SLAM pipelines. In particular, this thesis will look at two sensing modalities: acceleration and rotation rate measurements from an inertial measurement unit (IMU) to address the tracking issue, and learned priors on dense reconstructions from deep neural networks (DNNs) to address the mapping issue.
Antioxidant and Antiviral potential against SARS-CoV-2 of citrus limonoids isolated from Grapefruit Seed Extracts
Creators: name: SUCAMELI, MARZIA
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: The COVID-19 pandemic represented an unprecedented global emergency. Despite all efforts, COVID-19 remains a threat to public health, due to the complexity of mass vaccination programs, the lack of effective drugs, and the emergence of new variants. A link has recently been found between the risk of developing a severe COVID-19 infection and a high level of oxidative stress. In this context, we have focused our attention on natural compounds with the aim of finding molecules capable of acting through a dual antiviral / antioxidant mechanisms. In particular, we studied the potential of grapefruit seed extracts (GSE) and their main components, belonging to the class of limonoids. Using several physical and biological approaches including isolation and purification of GSE, oxidative and viability and antiviral assays, we have shown that extracts, particularly extract components belonging to the class of limonoids, are endowed with remarkable virucidal, antioxidant and mitoprotective activity.
General Solution of a Fractional Diffusion-Advection Equation for Solar Cosmic-Ray Transport
Creators: name: Rocca, M. C.
name: Plastino, A. R.
name: Plastino, A.
name: De Paoli, A. L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In this effort we exactly solve the fractional diffusion-advection equation for solar cosmic-ray transport proposed in \cite{LE2014} and give its {\it general solution} in terms of hypergeometric distributions. Also, we regain all the results and approximations given in \cite{LE2014} as {\it particular cases} of our general solution.
description: 12 pages, no figures
Distributed coordination of flexible devices in power networks
Creators: name: Gong, Xuan
Publisher: name: Imperial College London
Year: 2020

description: The penetration of new types of devices, such as domestic storage and electric vehicles, offers increasing flexibility on demand side. This will bring both new opportunities and challenges to the operation of power systems. The aim of this thesis is to design novel distributed control strategies for large scale coordination of flexible devices. To this end, flexible devices are modelled as self-interested rational agents that aim at minimizing their individual costs in response to the broadcast price signals. This thesis mainly consists of three parts, considering that the price signals can be designed in different forms, and that flexible devices could operate in different markets (e.g. energy markets, and integrated energy and reserve markets). The first part presents a multi-agent framework for the coordination of large populations of micro-storage devices in energy markets, under the assumption that the electricity price is some monotone increasing function of total power demand. The second part extends the work of the first part through taking into account the topology of power networks: the proposed modelling framework envisages heterogeneous groups of loads that operate at different buses, connected by transmission lines of limited capacity. The locational marginal prices of electricity are used as price signals, which are different in general for each bus and calculated through an optimal power flow problem. In the framework of the third part, it is envisioned that micro-storage devices and electric vehicles participate in an integrated energy-reserve market, and that they can contribute to the provision of reserve by being available to reduce their power consumption. These flexible devices autonomously schedule their operation in response to two kinds of price signals - the locational marginal prices of energy and reserve. Iterative schemes for the coordination of the flexible devices are presented in the three parts. It is proved that the proposed coordination schemes can ensure the convergence to stable market configurations, characterized as aggregative equilibria at which each device cannot further reduce its cost by unilaterally changing its power profile. Distributed implementations of these proposed control strategies are discussed, and their performance is evaluated in simulations on large scale power systems.
Sonnenfleckenzeichnung Nr. 131.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.06.2010, 06:45, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Route to chaos in generalized logistic map
Creators: name: Rak, Rafał
name: Rak, Ewa
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Motivated by a possibility to optimize modelling of the population evolution we postulate a generalization of the well-know logistic map. Generalized difference equation reads: \begin{equation} x_{n+1}=rx^p_n(1-x^q_n), \end{equation} $x\in[0,1],\;(p,q)>0,\;n=0,1,2,...$, where the two new parameters $p$ and $q$ may assume any positive values. The standard logistic map thus corresponds to the case $p=q=1$. For such a generalized equation we illustrate the character of the transition from regularity to chaos as a function of $r$ for the whole spectrum of $p$ and $q$ parameters. As an example we consider the case for $p=1$ and $q=2$ both in the periodic and chaotic regime. We focus on the character of the corresponding bifurcation sequence and on the quantitative nature of the resulting attractor as well as its universal attribute (Feigenbaum constant).
description: Accepted for publication in Acta Physica Polonica A, 12 pages, 6 figures, 1 table
Structure-phase behavior-performance relationships in non-fullerene acceptor based organic solar cells: insight from thermal and spectroscopic characterization
Creators: name: Hamid, Zeinab
Publisher: name: Imperial College London
Year: 2019

description: In the context of increasing interest in faster material screening and blend component selection for organic solar cells, this thesis explores thermal analysis as a tool towards a more in-depth understanding of the relationship between material structure, phase behavior and performance in organic solar cells (OSCs). Firstly, the phase behavior of PffBT4T-2DT/O-IDTBR polymer donor/non-fullerene acceptor (NFA) system is investigated using differential scanning calorimetry. The observed monotectic temperature-composition (T-Φ) diagram is used to rationalize optimal donor/acceptor (D/A) ratio in devices based on morphological changes, and is supplemented by transient absorption spectroscopy and X-ray techniques to probe the morphology in thin films directly. It was found that a D/A ratio within the inferred miscibility gap induces excessively large polymer domains which are not well interconnected, thus limiting performance. Secondly, the relationship between phase behavior and device performance is further explored in P3HT blends with either O-IDTBR or EH-IDTBR, where it was found that the dependence of eutectic composition on Mw in blends with the former acceptor correlates with a dependence of performance, while both eutectic composition and performance are largely invariant in blends with the latter. This difference was attributed to the difference in degree of crystallinity of the two acceptors, which is further explored in the fourth chapter where acceptor crystallization kinetics and phase structure are investigated using differential scanning calorimetry and variable temperature X-ray diffraction. It was found that O-IDTBR crystallization persists at faster rates compared to EH-IDTBR. The latter acceptor was found to form a liquid crystalline phase that is more robust towards fast rates compared to the crystalline phase.
(502214) William Winship
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Sonnenfleckenzeichnung Nr. 24.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.01.2010, 08:45, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 165.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.07.2010, 07:30, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Lipid synthesis and secretion by primary cultures of rat mammary epithelial cells
Creators: name: Rohlfs, E.M.
name: Zeisel, S.H.
name: Louie, D.S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Lipid synthesis and secretion was measured in primary rat mammary epithelial cells cultured on basement matrix in medium supplemented with lactogenic hormones. The cells grew and differentiated to form alveolar‐like structures reminiscent of lactating mammary gland. They synthesized abundant triacylglycerol, containing fatty acids characteristic of rat milk (C10:O‐C14:0), using 14C‐glucose, 14C‐oleic acid or 14C‐glycerol as precursors. Basal levels of triacylglycerol secretion were measured using 14C‐oleic acid labeling; 1.3±0.3% of the labeled cellular triacylglycerol was secreted into the medium in 24 hours. Secreted lipid droplets were surrounded by a bilayer membrane with an electron‐dense inner coat characteristic of fat globules secreted by the mammary gland. The rate of triglycerol secretion was increased to 998±98% of control (P<0.01) by the addition of phorbol 12‐myristate 13‐acetate (PMA) in combination with staurosporine, a protein kinase inhibitcn. Several other protein kinase inhibitors, when combined with PMA, also markedly stimulated secretion. Effective protein kinase inhibitors included sphingosine (has diverse cellular effects including the inhibition of protein kinase C; 13‐fold increase in secretion), and KT5823 (a cGMP dependent protein kinase inhibitor; 5‐fold increase). KT5720 (a cAMP‐dependent protein kinase inhibitor) did not alter secretion. Kinase inhibitors were effective only in the presence of a phorbol ester. 4α‐phorbol‐12,13‐didecanoate, a phorbol ester which does not activate protein kinase C (PKC), could substitute for PMA. Lipid release was not mediated by disruption of cell‐cell tight junctions, as EGTA did not release lipid. Based on these observations we suggest that two signals are needed to enable or stimulate lipid secretion in cultured rat mammary epithelial cells: (1) inhibition of a protein kinase and (2) a PKC‐independent effect of phorbol ester. We have, for the first time, characterized a cell culture model suitable for studying lipid synthesis and secretion by mammary epithelial cells.
Sistema politico e corruzione
Creators: name: FREGA, SIMONE
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: The dissertation analyzes the phenomenon of political corruption in the Italian legal system. The first chapter deals with the origin of parties, their provisions in the Italian Constitution and the possibilities to regulate the internal democracy of these particular social formation. The second chapter focuses on the relationship between the corruption scandals in the Italian political context and the insufficient legislative interventions concerning political parties. In the third chapter and in the conclusion, the attention is oriented on the measures to contrast corruption on a national and international level and, consequently, on the possible regulatory interventions that Italy would need to contain political corruption.
Choline, an essential nutrient for humans
Creators: name: Sheard, N.F.
name: Alexander, E.A.
name: Da Costa, K.-A.
name: Beiser, A.
name: Franklin, P.D.
name: Zeisel, S.H.
name: Lamont, J.T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1991

description: Choline is required to make essential membrane phospholipids. It is a precursor for the biosynthesis of the neurotransmitter acetylcholine and also is an important source of labile methyl groups. Mammals fed a choline-deficient diet develop liver dysfunction; however, choline is not considered an essential nutrient in humans. Healthy male volunteers were hospitalized and fed a semisynthetic diet devoid of choline supplemented with 500 mg/day choline for 1 wk. Subjects were randomly divided into two groups, one that continued to receive choline (control), and the other that received no choline (deficient) for three additional wk. During the 5th wk of the study all subjects received choline. The semisynthetic diet contained adequate, but no excess, methionine. In the choline-deficient group, plasma choline and phosphatidylcholine concentrations decreased an average of 30% during the 3-wk period when a choline-deficient diet was ingested; plasma and erthrocyte phosphatidylcholine decreased 15%; no such changes occurred in the control group. In the choline-deficient group, serum alanine aminotransferase activity increased steadily from a mean of 0.42 μkat/liter to a mean of 0.62 μkat/liter during the 3-wk period when a choline-deficient diet was ingested; no such change occurred in the control group. Other tests of liver and renal function were unchanged in both groups during the study. Serum cholesterol decreased an average of 15% in the deficient group and did not change in the control group. Healthy humans consuming a choline-deficient diet for 3 wk had depleted stores of choline in tissues and developed signs of incipient liver dysfunction. Our observations support the conclusion and choline is an essential nutrient for humans when excess methionine and folate are not available in the diet.
title: Triggering Lightning Experiments: an Effective Approach to the Research of Lightning Physics
Creators: name: Qie, X.
name: Jiang, R.
name: Laroche, P.
Publisher: name: ONERA
Year: 2012

description: Artificial triggering lightning experiments by launching a small rocket trailing a thin
wire toward a charged cloud overhead have been conducted since the 1960s. After
decades of development, this has become an important means for investigating lightning
physics and validating lightning protection and location techniques. Observations
of the triggered lightning have provided considerable new insights into different aspects
of lightning discharges. This paper presents an overview of worldwide artificial triggering
lightning experiments by means of the rocket-and-wire technique. Some valuable
results, including properties of upward positive leader (UPL), observational evidence
for the leader stepping mechanism, return stroke currents, M component properties,
and energetic radiation associated with the lightning discharges, are briefly reviewed.
description: Journal Aerospace Lab, Issue 5, December 2012; ISSN: 2107-6596
Full-waveform inversion in three-dimensional PML-truncated elastic media
Creators: name: Fathi, Arash
name: Kallivokas, Loukas F.
name: Poursartip, Babak
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65L09, 65F08

description: We are concerned with high-fidelity subsurface imaging of the soil, which commonly arises in geotechnical site characterization and geophysical explorations. Specifically, we attempt to image the spatial distribution of the Lame parameters in semi-infinite, three-dimensional, arbitrarily heterogeneous formations, using surficial measurements of the soil's response to probing elastic waves. We use the complete waveform response of the medium to derive the inverse problem, by using a partial-differential-equation (PDE)-constrained optimization approach, directly in the time-domain, to minimize the misfit between the observed response of the medium at select measurement locations, and a computed response corresponding to a trial distribution of the Lame parameters. We discuss strategies that lend algorithmic robustness to our proposed inversion scheme. To limit the computational domain to the size of interest, we employ perfectly-matched-layers (PMLs). In order to resolve the forward problem, we use a recently developed hybrid finite element approach, where a displacement-stress formulation for the PML is coupled to a standard displacement-only formulation for the interior domain, thus leading to a computationally cost-efficient scheme. Time-integration is accomplished by using an explicit Runge-Kutta scheme, which is well-suited for large-scale problems on parallel computers. We verify the accuracy of the material gradients obtained via our proposed scheme, and report numerical results demonstrating successful reconstruction of the two Lame parameters for both smooth and sharp profiles.
description: Submitted Journal Paper
Sonnenfleckenzeichnung Nr. 45.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.02.2010, 08:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
(502215) Isabel [Winship]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Metal oxide nanocrystals for light-driven energy storage
Creators: name: GHINI, MICHELE
Publisher: name: Universit� degli studi di Genova
Year: 2022

description: In a world struggling to face the disruptive consequences of global warming, developing new energy conversion and storage solutions is of fundamental importance. This PhD thesis focuses on emerging heterostructures based on Indium Tin Oxide nanocrystals (ITO NCs) and two-dimensional Transition Metal Dichalcogenides (2D TMDs) for innovative light-driven optoelectronic nanodevices and energy storage solutions, combining the harvesting, conversion and storage aspects into a unique hybrid nanomaterial. Doped Metal Oxide (MO) NCs are attracting growing interest as nano-supercapacitors due to their ability to store extra charges in their electronic structure with record-high values of capacitance. Remarkably, these materials can be charged with light (i.e., photodoping), a process at the core of this project and so far not understood electronically. Here, the fundamental features involved in the charge accumulation process are investigated and the physics of photodoping explained. Complete control over energetic band bending and depletion layer engineering is demonstrated, exposing the key role of electronically depleted layers in core-shell NCs. Light-induced depletion layer modulation and band bending is the main mechanism responsible for the storage of extra charges in doped MO supercapacitors. Moreover, multi-electron transfer reversible reactions were observed in photodoped NCs when exposed to a frequently used electron acceptor. The coupling between ITO NCs and 2D TMDs allowed the implementation of a novel all-optical localized charge injection scheme for the manipulation of unperturbed 2D materials. Hybrid 0D-2D heterostructures proved all-solid-state photodoping possible, with promising charging dynamics and capacitance values. Theoretical modeling tools were developed, leading to the optimization of the charge storage capacity of 0D NCs. This work is of particular interest for the fabrication of the next-generation of nanostructured light-driven supercapacitors.
1,2-sn-Diacylglycerol accumulates in choline-deficient liver. A possible mechanism of hepatic carcinogenesis via alteration in protein kinase C activity?
Creators: name: Blusztajn, J.K.
name: Zeisel, S.H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1989

description: Choline deficiency is associated with triacylglycerol accumulation in the liver, and is the only nutritional state known to trigger hepatic cancer spontaneously. In two different experiments, rats were pair-fed for 6 weeks with control (0.2% choline), or choline-deficient (CD) (0.002% choline) diets. Hepatic choline and phosphocholine declined in CD animals to 54% and 16% of control levels, respectively. In control livers, 1,2-sn-diacylglycerol (1,2-sn-DAG) concentration was (in nmol/g wet wt) 144 (± 25; mean ± SE); while in CD livers it was 792 (± 140) in the first experiment. In the second experiment the values were 375 (± 26) and 1147 (± 74), respectively. 1,2-sn-DAG, a precursor of triacylglycerol, is an endogenous activator of protein kinase C (PKC). PKC is the presumed site of action of the tumor-promoting phorbol esters. We suggest that the 1,2-sn-DAG accumulating in CD liver could bind PKC, altering its activity, and thus contribute to the carcinogenic effect of CD diets.
Sonnenfleckenzeichnung Nr. 39.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.02.2010, 09:15, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Access and equity: the two most important aspects of applied learning
Creators: name: Rahimi, Muhammad
name: Ong, Keng Wee Kenneth
Publisher: name: Singapore Institute of Technology
Year: 2024

description: What’s more important than advancing access to applied learning experiences in higher education? It can provide students with practical skills and knowledge they’ll need for their future careers. All students, regardless of their background or prior achievements, should have the opportunity to develop these competencies.However, equity in these experiences makes sure that additional support is available to those who may need it, helping to level the playing field and enhance overall graduate employability. At the Singapore Institute of Technology, we have adopted multiple initiatives to advance access to and equity in applied learning.
Role of a SER immune suppressor in immune surveillance
Creators: name: Zeisel, S.
name: Oh, S.K.
name: Walker, J.
name: Ross, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1988

description: A potent immunosuppressor factor, known as SER (suppressive E-receptor factor) has been identified in the body fluids of cancer patients. SER has been proven to be immunochemically analogous to the fetal form of haptoglobin. In this paper, we examine the role of SER immune suppressor in the immune surveillance mechanism of the host, using an affinity-purified SER. As shown in this study, SER, at μg/ml concentrations, inhibits the T-cell proliferation induced with either monoclonal or polyclonal T-cell activators in vitro in human, and also inhibits the primary antibody response to T-dependent antigens in vivo in mice. Likewise, SER also inhibits the immunoglobulin synthesis of human B lymphocytes induced by a B-cell mitogen, pokeweed mitogen, in the presence of a tumour promotor, phorbol myristate acetate (PMA). In contrast to the T-dependent antibody response in vivo in mice or T-dependent mitogen response in vitro in human, SER does not interfere with the T-independent antibody responses to DNP-Ficoll or TNP-LPS in mice. SER also interferes with the natural killer cell function of human peripheral blood mononuclear cells. Although SER inhibits the phagocytic functions of human peripheral neutrophils, it requires at least 10-20 times the concentration of SER present in normal human plasma. Since this concentration of SER is attainable in the sera of solid tumour-bearing patients, highly elevated levels of SER could predispose the patients to microbial infections as well. This study demonstrates that purified SER manifests multi-faceted down-regulatory effects on the defence mechanism of hosts, thereby it could compromise the patients' cell-mediated immunity in vivo.
(502208) Thomas King
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Sonnenfleckenzeichnung Nr. 285.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.12.2010, 09:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Experimental Studies of Lightning Strikes to Aircraft
Creators: name: Laroche, P.
name: Blanchet, P.
name: Delannoy, A.
name: Issac, F.
Publisher: name: ONERA
Year: 2012

description: Civil aviation transportation has been growing since the early forties and has become today a massive and unique transport system for people across continents and large countries. First age propeller airliners flew at low altitude and were often subjected to dangerous atmospheric and cloud hazards. Low visibility, heavy precipitation, severe turbulence, wind shear, icing and lightning are common weather hazards that are a challenge for flight safety. Among those weather hazards, lightning was the most unrecognized and misunderstood. Damages to aircraft due to lightning strike were frequently noticed; they range from arc spots on metal to centimeter-size holes in the fuselage, and dielectric radome and antenna destruction. Some cases of catastrophic events are directly attributed to lightning. Experimental in-situ studies were initiated no later than the early sixties, but the main in-flight research efforts were undertaken at the beginning of the eighties, when the perspective of a massive use of composite material in aviation was identified for a near future. Three major in-flight test programs were initiated in the USA and Europe by NASA, the Air Force, the FAA and the French Civil and Military Aviation Authorities, associated with Research Organizations. This paper is a review of the in-flight lightning strike experiments performed during that period. Information on aircraft missions, performances and instrumentation is given. Available results and proposed interpretations are presented. The main outcomes of those experiments are emphasized and knowledge gaps and missing information are mentioned.
description: Journal Aerospace Lab, Issue 5, December 2012; ISSN: 2107-6596
Surreal numbers, derivations and transseries
Creators: name: Berarducci, Alessandro
name: Mantova, Vincenzo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics
subject: 03C64, 16W60, 04A10, 26A12, 13N15

description: Several authors have conjectured that Conway's field of surreal numbers, equipped with the exponential function of Kruskal and Gonshor, can be described as a field of transseries and admits a compatible differential structure of Hardy-type. In this paper we give a complete positive solution to both problems. We also show that with this new differential structure, the surreal numbers are Liouville closed, namely the derivation is surjective.
description: 47 pages; minor corrections and typographical improvements
Sonnenfleckenzeichnung Nr. 18.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.01.2010, 09:30, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
(502209) Isabella [King]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Accessible air quality forecasts for Arctic communities: how AI can help citizens and policy-makers
Creators: name: Crotti, Ilaria
name: Cuzzucoli, Alice
name: De Marchi, Davide
name: Ramalli, Edoardo
name: Eyraud, Franck
name: Selmi, Luigi
name: PASINI, ANTONELLO
name: DOBRICIC, Srdan
Publisher: name: Zenodo
Year: 2024

description: Presentation at the 2024 European Polar Science Week (Copenhagen) - Session: The Real World Impact of AI in the Polar Regions
title: A Physical Model of Branching in Upward Leaders
Creators: name: Lalande, P.
name: Mazur, V.
Publisher: name: ONERA
Year: 2012

description: The physical processes leading to branching and physical factors affecting branching
features are poorly understood. We are applying the tested physical model
of axisymmetrical leader development following the streamer-leader transition to a
3-dimensional propagation of the leader with branching. The propagation of the leader
is driven by the potential drop at the leader tip. The branching occurs when the drop
potential at the leader tip reaches a threshold. The space charge around the leaders self
regulates the total number of active branches by reducing the available potential for the
propagation. The model has been applied to simulate the time evolution of an upward
leader started from a tall ground structure and developing in an electric field produced
by a mature thunderstorm. We are satisfied with the fact that the results of computer
simulation of branching leader closely resemble branching of upward positive leaders
triggered by tall structures depicted in high-speed video images.
description: Journal Aerospace Lab, Issue 5, December 2012; ISSN: 2107-6596
Orthogonal jumps of wavefunction in white-noise potentials
Creators: name: Diósi, Lajos
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the evolution of the quantum state for a free particle placed into a random external potential of white-noise type. The master equation for the density matrix is derived by means of path integral method. We propose an equivalent stochastic process where the wavefunction satisfies a nonlinear Schrödinger equation except for random moments at which it shows orthogonal jumps. The relation of our work to the usual theory of quantum noise and damping is briefly discussed.
description: 7pp, Modern title would be: Quantum trajectories of stochastic unravelling the master equation structure -[x,[x,rho]]
Sonnenfleckenzeichnung Nr. 12.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.01.2010, 08:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)