cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Emergent Spacetime and Holographic CFTs
Creators: name: El-Showk, Sheer
name: Papadodimas, Kyriakos
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss universal properties of conformal field theories with holographic duals. A central feature of these theories is the existence of a low-lying sector of operators whose correlators factorize. We demonstrate that factorization can only hold in the large central charge limit. Using conformal invariance and factorization we argue that these operators are naturally represented as fields in AdS as this makes the underlying linearity of the system manifest. In this class of CFTs the solution of the conformal bootstrap conditions can be naturally organized in structures which coincide with Witten diagrams in the bulk. The large value of the central charge suggests that the theory must include a large number of new operators not captured by the factorized sector. Consequently we may think of the AdS hologram as an effective representation of a small sector of the CFT, which is embedded inside a much larger Hilbert space corresponding to the black hole microstates.
description: 89 pages, 8 figures, typos corrected
Additional file 3 of A systematic review and meta-analysis of school-based interventions with health education to reduce body mass index in adolescents aged 10 to 19 years
Creators: name: Jacob, Chandni Maria
name: Hardy-Johnson, Polly Louise
name: Inskip, Hazel M.
name: Morris, Taylor
name: Parsons, Camille M.
name: Barrett, Millie
name: Hanson, Mark
name: Woods-Townsend, Kathryn
name: Baird, Janis
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 3:. PRISMA 2009 Checklist.
Bulk Milk Handling in 1955
Creators: name: Cowden, Joseph M.
name: Cowden, Joseph M.
Publisher: name: Unknown
Year: 1956
Subjects: subject: Agribusiness
subject: Land Economics/Use
subject: Marketing
subject: FOS: Economics and business
subject: Research and Development/Tech Change/Emerging Technologies

description: Excerpts from the report: Data summarized in this report depicted the extent and nature of the adoption of bulk methods of farm-to-plant transportation of milk as of March 1955. The nationwide mail survey which was the source of information for this summary followed a similar survey conducted in May 1953. Results of the 1953 survey were summarized and discussed in considerable detail in FCS Circular 8, Progress in Farm-to-Plant Bulk Milk Handling issued in November 1954 by Farmer Cooperative Service. The principal change occurring between the dates of the two surveys was in the numbers of plants and producers using bulk handling methods. Except for the numbers of plants, trucks and producers involved, the description and discussion of methods and practices presented in Circular 8 were largely applicable to this later survey. Accordingly, this report is limited to a presentation of statistical data with brief comments on important characteristics of the development. The survey covered the entire country except California and Florida. We made no attempt to obtain data from dairy firms in California due to the known extensive use of the bulk system in that State and the fact that production conditions prevailing there are not comparable with those in other Pacific Coast States or in other dairy production areas.
Acceleration of particles as universal property of rotating black holes
Creators: name: Zaslavskii, Oleg B.
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We argue that the possibility of having infinite energy in the centre of mass frame of colliding particles is a generic property of rotating black holes. We suggest a general model-independent derivation valid for "dirty" black holes. The earlier observations for the Kerr or Kerr-Newman metrics are confirmed and generalized.
description: 9 pages. Discussion expanded
title: ÐÑÐ¸ÐµÐ¼Ð½Ð¸Ðº ÑÐ¸Ð³Ð½Ð°Ð»Ð¾Ð² CDMA
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: A receiver for CDMA signals
Creators: name: ÐÐ¿Ð¸ÑÐ°Ð½Ð¾Ð²Ð°, ÐÐ°ÑÐ°Ð»Ð¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: Ð¼Ð½Ð¾Ð³Ð¾Ð»ÑÑÐµÐ²Ð¾ÑÑÑ
rake-Ð¿ÑÐ¸ÐµÐ¼Ð½Ð¸Ðº
ÑÐºÑÐµÐ¼Ð±Ð»Ð¸ÑÑÑÑÐ¸Ðµ ÐºÐ¾Ð´Ñ
Ð¿Ð¸Ð»Ð¾ÑÐ½ÑÐ¹ ÐºÐ°Ð½Ð°Ð»
ÐºÐ°Ð½Ð°Ð» ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ
multipath
CDMA
UMTS
rake-receiver
scrambling codes
pilot channel
control channel

description: Ð ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð° Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð°Ñ Ð¼Ð¾Ð´ÐµÐ»Ñ Ð´Ð»Ñ Ð»Ð°Ð±Ð¾ÑÐ°ÑÐ¾ÑÐ½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð¿Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð¾Ð¹ÑÑÐ² ÑÐ¸Ð³Ð½Ð°Ð»Ð¾Ð² CDMA. ÐÐ° Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ð¸ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð½Ð¾Ð¹ Ð¼Ð¾Ð´ÐµÐ»Ð¸ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð²Ð»Ð¸ÑÐ½Ð¸Ñ Ð·Ð½Ð°ÑÐµÐ½Ð¸Ñ ÐºÐ¾ÑÑÑÐ¸ÑÐ¸ÐµÐ½ÑÐ° ÑÐ°ÑÑÐ¸ÑÐµÐ½Ð¸Ñ Ð¸ Ð½Ð°Ð»Ð¸ÑÐ¸Ñ ÑÐºÑÐµÐ¼Ð±Ð»Ð¸ÑÑÑÑÐµÐ¹ Ð¿Ð¾ÑÐ»ÐµÐ´Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð½Ð° Ð¿Ð¾Ð¼ÐµÑÐ¾ÑÑÑÐ¾Ð¹ÑÐ¸Ð²Ð¾ÑÑÑ Ð¿ÑÐ¸ÑÐ¼Ð° ÑÐ¸Ð³Ð½Ð°Ð»Ð¾Ð² CDMA Ð² ÑÑÐ»Ð¾Ð²Ð¸ÑÑ Ð¼Ð½Ð¾Ð³Ð¾Ð»ÑÑÑÐ²Ð¾ÑÑÐ¸. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¾ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ ÐºÐ°ÑÐµÑÑÐ²Ð° Ð¿ÑÐ¸ÑÐ¼Ð° ÑÐ¸Ð³Ð½Ð°Ð»Ð¾Ð² Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ rake-Ð¿ÑÐ¸ÑÐ¼Ð½Ð¸ÐºÐ° Ð¿ÑÐ¸ ÑÐ°Ð·Ð½ÑÑ Ð·Ð½Ð°ÑÐµÐ½Ð¸ÑÑ ÑÐ¸ÑÐ»Ð° ÑÑÐ¸ÑÑÐ²Ð°ÐµÐ¼ÑÑ Ð»ÑÑÐµÐ¹ Ð¸ Ð´Ð»Ñ ÑÐ°Ð·Ð½ÑÑ ÑÐ¿Ð¾ÑÐ¾Ð±Ð¾Ð² Ð¾ÑÐµÐ½ÐºÐ¸ ÐºÐ°Ð½Ð°Ð»Ð°.
description: This work presents a program model developed for a laboratory project on research of CDMA signals' properties. The model instructed the research of influence of expansion coefficient and existence of a scrambling sequence on immunity of CDMA signals reception under multipath propagation A comparison of signals reception quality was carried out with the help of rake-receiver under different values of the number of the rays taken into account and for different ways of channel evaluation.
Additional file 1 of Significance of kidney biopsy in autosomal dominant tubulointerstitial kidney disease-UMOD: is kidney biopsy truly nonspecific?
Creators: name: Tamehito Onoe
name: Hara, Satoshi
name: Yamada, Kazunori
name: Zoshima, Takeshi
name: Mizushima, Ichiro
name: Kiyoaki Ito
name: Mori, Takayasu
name: Daimon, Shoichiro
name: Muramoto, Hiroaki
name: Shimizu, Maki
name: Iguchi, Akira
name: Kuma, Akihiro
name: Ubara, Yoshifumi
name: Mitobe, Michihiro
name: Tsuruta, Hiroaki
name: Kishimoto, Nao
name: Imura, Junko
name: Konoshita, Tadashi
name: Kawano, Mitsuhiro
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1 : Supplemental table 1. pathogenicity prediction of each UMOD variant
Unwinding dynamics of double-stranded polymers
Creators: name: Baiesi, M.
name: Barkema, G. T.
name: Carlon, E.
name: Panja, D.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biomolecules (q-bio.BM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: We consider the unwinding of two lattice polymer strands of length N that are initially wound around each other in a double-helical conformation and evolve through Rouse dynamics. The problem relates to quickly bringing a double-stranded polymer well above its melting temperature, i.e., the binding interactions between the strands are neglected, and the strands separate from each other as it is entropically favorable for them to do so. The strands unwind by rotating around each other until they separate. We find that the process proceeds from the ends inward; intermediate conformations can be characterized by a tightly wound inner part, from which loose strands are sticking out, with length l~t^0.39. The total time needed for the two strands to unwind scales as a power of N as tu~N^(2.57+-0.03). We present a theoretical argument, which suggests that during this unwinding process, these loose strands are far out of equilibrium.
description: 12 pages, 4 figures
Additional file 1 of Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis
Creators: name: Nanamika Thakur
name: Kupani, Manu
name: Rashim Mannan
name: Pruthi, Archna
name: Mehrotra, Sanjana
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. The Newcastle-Ottawa Scale for the assessment of case-control studies included in the meta-analysis.
Behavioural effects of D2/3 and D3 agonist drugs : implications for iatrogenic impulse control disorders
Creators: name: Brodie, Hannah
Publisher: name: University of British Columbia
Year: 2022

description: The chronic use of dopamine agonist drugs to treat diseases such as Parkinson’s has been associated with the development of impulse control disorders. It is hypothesized that this mainly occurs through action at D3 receptors thereby inducing sensitization of the mesolimbic dopamine system, increasing impulsivity and risky decision making. Using a preclinical model, I tested the effects of chronic ropinirole, a commonly prescribed D2/3 receptor agonist, on performance on the rodent gambling task in healthy female rats. I subsequently investigated the effect of chronic D3 receptor activation via a selective agonist on rGT performance in male rats. The data I present in this thesis suggests that ropinirole does not have the same risk promoting effects in female rats as it does in males. Additionally, my data challenges the hypothesis that D3 receptors are solely responsible for the increase in risky decision making caused by ropinirole in males.
Patrimonial economic voting: a cross-national analysis of asset ownership and the vote
Creators: name: Quinlan, Stephen
name: Okolikj, Martin
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Our study examines the impact possession of assets (patrimony) has on the vote in 34 countries. We provide the first comprehensive test of patrimony on the vote cross-nationally. Using Module 4 of the Comparative Study of Electoral Systems (CSES) and hierarchical models, we show that asset ownership matters and has a direct effect on the vote in several countries. More assets increase the likelihood of supporting the right. In other nations, its effect is indirect or absent. Accounting for this macro variation, we show that patrimonial voting is stronger in liberal welfare states and in countries where the tax system does not limit incentives to invest. However, we find no evidence that patrimonial voting is conditioned by ideological polarization. Our research highlights that economic voting is multidimensional and that patrimony, especially in some countries, is a potent determinant of the vote.
Colliding AdS gravitational shock waves in various dimensions and holography
Creators: name: Duenas-Vidal, Alvaro
name: Vazquez-Mozo, Miguel A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The formation of marginally trapped surfaces in the off-center collision of two shock waves on AdS_D (with D=4,5,6,7 and 8) is studied numerically. We focus on the case when the two waves collide with nonvanishing impact parameter while the sources are located at the same value of the holographic coordinate. In all cases a critical value of the impact parameter is found above which no trapped surface is formed. The numerical results show the existence of a simple scaling relation between the critical impact parameter and the energy of the colliding waves. Using the isometries of AdS_D we relate the solutions obtained to the ones describing the collision of two waves with a purely holographic impact parameter. This provides a gravitational dual for the head-on collision of two lumps of energy of unequal size.
description: 25 pages, 11 figures. v2: minor changes, typos corrected. To appear in JHEP
Additional file 1 of MiR-200c/FUT4 axis prevents the proliferation of colon cancer cells by downregulating the Wnt/β-catenin pathway
Creators: name: Jinchun Cong
name: Gong, Jian
name: Chuanjia Yang
name: Zhixiu Xia
name: Zhang, Hong
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 1: Supplementary Figure 1. The original blots of Ki-67, FUT4, β-catenin, Cyclin D1, p-GSK-3β, GSK-3β in Lovo and SW480 cells. (Corresponding to Fig. 6 in the manuscript).
Crisis and extremism. How does an extreme far right emerge in a modern democracy? Evidence from Greece’s Golden Dawn
Creators: name: Roumanias, Costas
name: Skouras, Spyros
name: Christodoulakis, Nicos
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 60506 Virology

description: We trace the rise of Golden Dawn, one of the most extreme and violent European far-right parties, from the fringe to a prominent position in Greek politics. We use regression analysis to show that its rise is associated with changes in voting behavior caused by the deep socioeconomic crisis the country went through after 2008. We show that the demand factors affecting the GD vote were triggered by structural changes in the supply side and the implosion of the two-party system that followed the signing of the bail-out agreement (Memorandum) with the country’s creditors. Our results have implications about the political manifestation of socioeconomic grievances and their effect on the far-right vote: whereas socioeconomic grievances usually contribute towards a latent dissatisfaction by the electorate, this might need a sudden supply-side trigger in order to manifest itself, giving little warning signs in advance.
Fatores que influenciam a satisfação do cliente crítico com o cuidado de enfermagem: scoping review
Creators: name: Andrez, Susana
name: Sousa, Patrícia Pontífice
name: Marques, Rita
Publisher: name: Cadernos de Saúde
Year: 2021

description: Cadernos de Saúde, v. 12 n. Especial (2020): Enfermagem especializada
Fatores que influenciam a adesão dos profissionais de saúde (médicos e enfermeiros) às boas práticas clínicas: uma scoping review
Creators: name: Santos, Ana Luísa
name: Sousa, Liliana
name: Ildefonso, Tatiana
name: Veludo, Filipa
name: Sousa, Patrícia
name: Marques, Rita
Publisher: name: Cadernos de Saúde
Year: 2021

description: Cadernos de Saúde, v. 12 n. Especial (2020): Enfermagem especializada
Policy area satisfaction, perceptions of responsibility, and political trust: a novel application of the REWB model to testing evaluation-based political trust
Creators: name: de Blok, Lisanne
name: van der Meer, Tom
name: Van der Brug, Wouter
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Existing research demonstrates that evaluations of policies affect political trust. However, two limitations to the extant literature require us to reassess the micro-level foundation of the dominant trust-as-evaluation approach. Empirically, the common test of the evaluation-trust link relies on comparisons between individuals, an approach that suffers from endogeneity problems. Theoretically, the evaluation-trust link should be conditional on perceptions of government responsibility. Yet, this moderator is not included in most studies. We address these limitations in tandem. We study the conditionality of the evaluation-trust link on perceptions of government responsibility, using an innovative application of the Random Effects Within-Between (REWB) model, which simultaneously analyses variation between and within respondents. While our findings provide specific support for the (conditional) evaluation-trust link, we conclude that the literature has been overly optimistic when relying on between-respondent analyses.
Intervenções utilizadas para a prevenção de hábitos alcoólicos nos adolescentes
Creators: name: Domingos, Cláudia
name: Barbosa, Conceição
name: Fortunato, Kátia
name: Ferrito, Cândida
Publisher: name: Cadernos de Saúde
Year: 2021

description: Cadernos de Saúde, v. 12 n. Especial (2020): Enfermagem especializada
On the falloff of radiated energy in black hole spacetimes
Creators: name: Burko, Lior M.
name: Hughes, Scott A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The goal of much research in relativity is to understand gravitational waves generated by a strong-field dynamical spacetime. Quantities of particular interest for many calculations are the Weyl scalar $ψ_4$, which is simply related to the flux of gravitational waves far from the source, and the flux of energy carried to distant observers, $\dot E$. Conservation laws guarantee that, in asympotically flat spacetimes, $ψ_4 \propto 1/r$ and $\dot E \propto 1/r^2$ as $r \to \infty$. Most calculations extract these quantities at some finite extraction radius. An understanding of finite radius corrections to $ψ_4$ and $\dot E$ allows us to more accurately infer their asymptotic values from a computation. In this paper, we show that, if the final state of the system is a black hole, then the leading correction to $ψ_4$ is ${\cal O}(1/r^3)$, and that to the energy flux is ${\cal O}(1/r^4)$ --- not ${\cal O}(1/r^2)$ and ${\cal O}(1/r^3)$ as one might naively guess. Our argument only relies on the behavior of the curvature scalars for black hole spacetimes. Using black hole perturbation theory, we calculate the corrections to the leading falloff, showing that it is quite easy to correct for finite extraction radius effects.
description: 5 pages, no figures, accepted to Phys. Rev. D. This version corrects several typos and minor errors in the earlier submission
Sex differences in voluntary activation of the diaphragm
Creators: name: Ramsook, Andrew Harry
Publisher: name: University of British Columbia
Year: 2022

description: Purpose: Three studies were performed to examine how voluntary activation of the diaphragm changes after fatiguing tasks in young, healthy males and females. The change in diaphragm voluntary activation (D-VA) was also compared to the change in contractile function, assessed by the change in transdiaphragmatic twitch pressure (P¬DI,TW). Methods: Study 1 (Chapter 2) investigated the within- and between-session reliability of D-VA using cervical magnetic stimulation (CMS) to evoke twitches. Study 2 (Chapter 3) examined changes in D-VA after high intensity, whole-body exercise between sexes. Study 3 (Chapter 4) examined changes in D-VA after inspiratory pressure threshold loading (IPTL) between sexes. Conclusions: CMS can be used to reliably assess D-VA, measured via intraclass correlation coefficients (ICC) both within- (ICC: 0.76) and between-session (ICC: 0.88). After exercise, D-VA decreased in males and females. The decrease in D-VA was greater in males compared to females (87.4±10.8 vs 95.4±4.9%basline, respectively, p=0.036). The magnitude of the decrease in D-VA was less than the decrease in PDI,TW (Males: 70.3±12.4, Females: 85.2±16.7%baseline, p=0.024). After IPTL, both males and females showed a decrease in D-VA and PDI,TW. While males showed a greater decrease in PDI,TW (73.3±12.1 vs 87.1±15.0%baseline, respectively, p=0.016) compared to females, the decrease in D-VA was similar between sexes (88.2±10.5 vs 91.4±7.6%baseline, respectively, p=0.432). After IPTL, the decrease in PDI,TW correlated with the total respiratory work performed whereas the decrease in D-VA correlated with time until task failure. The magnitude of the decrease in PDI,TW was greater than the decrease in D-VA after IPTL. Collectively, the results of this thesis suggest that there are sex differences in the change in D-VA after exercise but not IPTL. This thesis provides a foundation for future work to investigate how diaphragm fatigability can affect exercise performance in humans.
Additional file 2 of MiR-200c/FUT4 axis prevents the proliferation of colon cancer cells by downregulating the Wnt/β-catenin pathway
Creators: name: Jinchun Cong
name: Gong, Jian
name: Chuanjia Yang
name: Zhixiu Xia
name: Zhang, Hong
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 2: Supplementary Figure 2. The original blots of Ki-67, FUT4, β-catenin, Cyclin D1, p-GSK-3β, GSK-3β in Lovo and SW480 cells. (Corresponding to Fig. 8 in the manuscript).
Parallel Sparse Matrix Solver on the GPU Applied to Simulation of Electrical Machines
Creators: name: Rodrigues, Antonio Wendell De Oliveira
name: Guyomarch, Frédéric
name: Menach, Yvonnick Le
name: Dekeyser, Jean-Luc
Publisher: name: arXiv
Year: 2010
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: Nowadays, several industrial applications are being ported to parallel architectures. In fact, these platforms allow acquire more performance for system modelling and simulation. In the electric machines area, there are many problems which need speed-up on their solution. This paper examines the parallelism of sparse matrix solver on the graphics processors. More specifically, we implement the conjugate gradient technique with input matrix stored in CSR, and Symmetric CSR and CSC formats. This method is one of the most efficient iterative methods available for solving the finite-element basis functions of Maxwell's equations. The GPU (Graphics Processing Unit), which is used for its implementation, provides mechanisms to parallel the algorithm. Thus, it increases significantly the computation speed in relation to serial code on CPU based systems.
A brincadeira terapêutica enquanto intervenção de enfermagem numa urgência pediátrica
Creators: name: Guerra, Nádia
name: Charepe, Zaida
name: Nunes, Elisabete
name: Lourenço, Margarida
name: Berenguer, Sílvia
Publisher: name: Cadernos de Saúde
Year: 2021

description: Cadernos de Saúde, v. 12 n. Especial (2020): Enfermagem especializada
title:  Case Study: ROR in the COS Open Science Framework
Creators: name: French, Amanda
Publisher: name: Research Organization Registry (ROR)
Year: 2022
Subjects: classificationCode: 1.2
subject: FOS: Computer and information sciences

description: This conversation with Eric Olson of the Center for Open Science is the first in a new series of interviews, “Case Studies in ROR Integration,” a series designed to provide in-depth detail on why and how people are choosing to integrate ROR IDs into their systems.
O ambiente de prática de enfermagem em contexto de unidade de cuidados intensivos: protocolo de scoping review
Creators: name: Melgueira, Isabel
name: Veludo, Filipa
Publisher: name: Cadernos de Saúde
Year: 2021

description: Cadernos de Saúde, v. 12 n. Especial (2020): Enfermagem especializada
Polarization Limits in K-Rb Spin-Exchange Mixtures
Creators: name: Lancor, Brian
name: Walker, Thad G.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We present measurements of the optical absorption of K vapor at 795 nm due to the presence of high pressure He gas. The results set a limit on the polarization attainable in hybrid spin-exchange optical pumping of He-3.
Additional file 1 of Home blood-pressure measurement for the diagnosis and monitoring of arterial hypertension by French general practitioners: a cross-sectional survey in the Auvergne region
Creators: name: Mangiavillano Xavier
name: Tréfond Jéromine
name: Plaquevent-Hostache Guillaume
name: Gilles, Tanguy
name: Bœuf-Gibot Sylvaine
name: Mulliez Aurélien
name: Vorilhon Philippe
Publisher: name: figshare
Year: 2021
Subjects: subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 1.
The extensive nature of group quality
Creators: name: Kenna, Ralph
name: Berche, Bertrand
Publisher: name: arXiv
Year: 2010
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider groups of interacting nodes engaged in an activity as many-body, complex systems and analyse their cooperative behaviour from a mean-field point of view. We show that inter-nodal interactions rather than accumulated individual node strengths dominate the quality of group activity, and give rise to phenomena akin to phase transitions, where the extensive relationship between group quality and quantity reduces. The theory is tested using empirical data on quantity and quality of scientific research groups, for which critical masses are determined.
description: 6 pages, 6 figures containing 13 plots. Very minor changes to coincide with published version
How conspiracy theories can stimulate political engagement
Creators: name: Kim, Yongkwang
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Although a growing body of studies has explored the antecedents of people’s adoption of conspiracy beliefs, the behavioral consequences of conspiracy theories – particularly regarding political engagement – have been less explored. Research has looked at conspiracy beliefs, exposure to specific conspiracy theories, conspiracy thinking, and the communication of conspiracy theories as predictor variables. To date, the findings are mixed due to conceptual differences and the selection of predictors with different functions and aspects. I offer new evidence. First, I explore whether conspiracy beliefs translate into political engagement. Having analyzed the 2012 American National Election Study, I find a positive association between conspiracy beliefs and political activities. Second, by manipulating exposure to a nascent conspiracy theory that emerged during the 2016 presidential primary elections, I examine whether exposure to conspiracy theories drives intention to engage in politics. Across two original survey experiments, the results indicate that conspiracy theories may lead to positive action, encouraging people to get involved in politics. The findings demonstrate that the spread of conspiracy theories is not uniformly detrimental to society. These findings also help to explain why elites within losing political organizations are more likely to spread conspiracy theories: they are a means for mobilizing disenfranchised citizens.
The free Dirac spinors of the spin basis on the de Sitter expanding universe
Creators: name: Cotaescu, Ion I.
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: It is shown that on the de Sitter space-time the global behavior of the free Dirac spinors in momentum representation is determined by several phases factors which are functions of momentum with special properties. Such suitable phase functions can be chosen for writing down the free Dirac quantum modes of the spin basis that are well-defined even for the particles at rest in the moving local charts where the modes of the helicity basis remain undefined. Under quantization these modes lead to a basis in which the one-particle operators keep their usual forms apart from the energy operator which lays out a specific term which depend on the concrete phase function one uses.
description: 8 pages no figures
title: ÐÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ðµ Ð¸Ð½ÑÐµÑÐ¿ÑÐµÑÐ°ÑÐ¸Ð¸ ÐºÑÐ¸Ð²Ð¾Ð¹ Ð²Ð¾ÑÑÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ñ Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸ÐµÐ¼ ÑÐ°Ð·Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð¸ÑÐºÐ¾Ð¼Ð¾Ð³Ð¾ ÑÐµÑÐµÐ½Ð¸Ñ Ð´Ð»Ñ ÑÐ°ÑÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿Ð¾ ÑÐ¾Ð±ÑÑÐ²ÐµÐ½Ð½ÑÐ¼ ÑÑÐ½ÐºÑÐ¸ÑÐ¼ Ð·Ð°Ð´Ð°ÑÐ¸ ÑÐ¸Ð»ÑÑÑÐ°ÑÐ¸Ð¸
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°Ð¼Ð°ÑÐ¾Ð², Ð¡ÐµÑÐ³ÐµÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2020
Subjects: ÐÐµÑÑÑÐ½ÑÐµ Ð¸ Ð³Ð°Ð·Ð¾Ð²ÑÐµ Ð¿Ð»Ð°ÑÑÑ
Ð½ÐµÑÑÑÐ½Ð¾Ð¹ Ð¸Ð½Ð¶Ð¸Ð½Ð¸ÑÐ¸Ð½Ð³
Ð¸Ð½ÑÐµÑÐ¿ÑÐµÑÐ°ÑÐ¸Ñ Ð³Ð´Ð¸Ñ
ÐºÑÐ¸Ð²Ð°Ñ Ð²Ð¾ÑÑÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ñ
ÑÐ¾Ð±ÑÑÐ²ÐµÐ½Ð½ÑÐµ ÑÑÐ½ÐºÑÐ¸Ð¸ Ð¸ Ð·Ð½Ð°ÑÐµÐ½Ð¸Ñ
Ð½Ð¸Ð·ÐºÐ¾Ð¿ÑÐ¾Ð½Ð¸ÑÐ°ÐµÐ¼ÑÐ¹ ÐºÐ¾Ð»Ð»ÐµÐºÑÐ¾Ñ

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð½Ð¾Ð²Ð¾Ð¼Ñ Ð¼ÐµÑÐ¾Ð´Ñ Ð¸Ð½ÑÐµÑÐ¿ÑÐµÑÐ°ÑÐ¸Ð¸ ÐºÑÐ¸Ð²Ð¾Ð¹ Ð²Ð¾ÑÑÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ñ Ñ ÑÐµÐ»ÑÑ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ Ð¿Ð»Ð°ÑÑÐ¾Ð²Ð¾Ð³Ð¾ Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ñ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÐ°Ð·Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð¸ÑÐºÐ¾Ð¼Ð¾Ð³Ð¾ ÑÐ°ÑÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿Ð¾ ÑÐ¾Ð±ÑÑÐ²ÐµÐ½Ð½ÑÐ¼ ÑÑÐ½ÐºÑÐ¸ÑÐ¼ Ð¸ Ð·Ð½Ð°ÑÐµÐ½Ð¸ÑÐ¼. ÐÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð½ÑÐ¹ Ð¼ÐµÑÐ¾Ð´ Ð¿ÑÐ¸Ð¼ÐµÐ½Ð¸Ð¼ Ð² ÑÑÐ»Ð¾Ð²Ð¸ÑÑ Ð½Ð¸Ð·ÐºÐ¾Ð¿ÑÐ¾Ð½Ð¸ÑÐ°ÐµÐ¼Ð¾Ð³Ð¾ ÐºÐ¾Ð»Ð»ÐµÐºÑÐ¾ÑÐ° Ð¸ Ð½ÐµÐ¾Ð´Ð½Ð¾ÑÐ¾Ð´Ð½Ð¾Ð³Ð¾ Ð¿Ð»Ð°ÑÑÐ°.
description: This paper describes the new method of interpreting pressure build-up to determine reservoir pressure based on the estimating eigenfunctions and eigenvalues from pressure distribution. The proposed method applicable in low-permeability and heterogeneous reservoirs cases.
Solving Bethe-Salpeter equation for two fermions in Minkowski space
Creators: name: Carbonell, J.
name: Karmanov, V. A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The method of solving the Bethe-Salpeter equation in Minkowski space, which we developed previously for spinless particles, is extended to a system of two fermions. The method is based on the Nakanishi integral representation of the amplitude and on projecting the equation on the light-front plane. The singularities in the projected two-fermion kernel are regularized without modifying the original Bethe-Salpeter amplitudes. The numerical solutions for the J=0 bound state with the scalar, pseudoscalar and massless vector exchange kernels are found. The stability of the scalar and positronium states without vertex form factor is discussed. Binding energies are in close agreement with the Euclidean results. Corresponding amplitudes in Minkowski space are obtained.
description: 11 pages, 9 figures, to be published in Eur. Phys. J. A
Additional file 1 of A study of the proficiency and performance of Iranian Air Traffic Controllers: attitude, work experience and specific aviation English courses
Creators: name: Rahmati, Massoud
name: Izadpanah, Siros
Publisher: name: figshare
Year: 2021
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1. Questionnaire.
Coleman-Weinberg mechanism in a three-dimensional supersymmetric Chern-Simons-matter model
Creators: name: Ferrari, A. F.
name: Gallegos, E. A.
name: Gomes, M.
name: Lehum, A. C.
name: Nascimento, J. R.
name: Petrov, A. Yu.
name: da Silva, A. J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Using the superfield formalism, we study the dynamical breaking of gauge symmetry in the N=1 three-dimensional supersymmetric Chern-Simons model, coupled to a complex scalar superfield with a quartic self-coupling. This is an analogue of the conformally invariant Coleman-Weinberg model in four spacetime dimensions. We show that a mass for the gauge and matter superfields are dynamically generated after two-loop corrections to the effective superpotential. We also discuss the N=2 extension of our work, showing that the Coleman-Weinberg mechanism in such model is not feasible, because it is incompatible with perturbation theory.
description: 14 pages, 2 figures. Minor corrections, references added. Journal version
Cuidadores formais e suas necessidades de educação para a saúde: conhecer no presente para atuar no futuro
Creators: name: Falcão, Helena
name: Santos, Irene
name: Fonseca, Isabel
name: Coelho, Rui
Publisher: name: Cadernos de Saúde
Year: 2021

description: Cadernos de Saúde, v. 12 n. Especial (2020): Enfermagem especializada
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð²ÐµÐ±-Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð´Ð»Ñ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¼ÐµÐ½Ñ Ð½Ð° Ð½ÐµÐ´ÐµÐ»Ñ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð²ÐºÑÑÐ¾Ð²ÑÑ Ð¿ÑÐµÐ´Ð¿Ð¾ÑÑÐµÐ½Ð¸Ð¹
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Development of a web application for forming a menu for a week based on taste preferences
Creators: name: ÐÑÑÐºÐ¾Ð²Ð°, ÐÐ½Ð°ÑÑÐ°ÑÐ¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: Ð²ÐµÐ±-Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ
firebase
react
web app

description: Ð ÑÐ°Ð¼ÐºÐ°Ñ Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð°ÑÑÐ²Ð°ÐµÑÑÑ Ð²ÐµÐ± Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ Ð´Ð»Ñ Ð³ÐµÐ½ÐµÑÐ°ÑÐ¸Ð¸ Ð¼ÐµÐ½Ñ Ñ ÑÐµÑÐµÐ¿ÑÐ°Ð¼Ð¸. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ñ ÑÐ°Ð±Ð¾ÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð¾ Ð²ÐµÐ± Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ, ÐºÐ¾ÑÐ¾ÑÐ¾Ðµ Ð¾ÑÑÑÐµÑÑÐ²Ð»ÑÐµÑ Ð³ÐµÐ½ÐµÑÐ°ÑÐ¸Ñ Ð¼ÐµÐ½Ñ Ñ ÑÐµÑÐµÐ¿ÑÐ°Ð¼Ð¸ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð²ÐºÑÑÐ¾Ð²ÑÑ Ð¿ÑÐµÐ´Ð¿Ð¾ÑÑÐµÐ½Ð¸Ð¹. ÐÐ»Ñ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð±ÑÐ» Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½ ÑÐ·ÑÐº Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ typescript, Ð±Ð¸Ð±Ð»Ð¸Ð¾ÑÐµÐºÐ° react Ð¸ Ð¿Ð»Ð°ÑÑÐ¾ÑÐ¼Ð° firebase.
description: As part of this work, a web application for generating a menu with recipes is being developed. As a result of the work, a web application was developed that generates a menu with recipes based on taste preferences. For development, the typescript programming language, the react library and the firebase platform were used.
Who will defend democracy? Evaluating tradeoffs in candidate support among partisan donors and voters
Creators: name: Carey, John
name: Clayton, Katherine
name: Helmke, Gretchen
name: Nyhan, Brendan
name: Sanders, Mitchell
name: Stokes, Susan
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: Scholars and pundits fear that the American public’s commitment to democracy is declining and that citizens are willing to embrace candidates who would trample democratic principles. We examine whether violations of those principles generate resistance from voters and/or top campaign donors and whether such resistance extends across partisan lines. In a conjoint survey experiment, we investigate how regular Americans and donor elites trade off partisanship, policy positions, and support for democratic values when choosing between hypothetical political candidates. Our findings indicate that both citizens and donors punish candidates who endorse violations of democratic principles irrespective of the candidate’s party. However, partisans react very differently to candidates who support voter identification laws that threaten access to the franchise. This polarized response is especially strong among donors. These results suggest that the public and donors may sometimes be willing to forgive transgressions against democratic norms that align with their partisan and policy preferences.
Additional file 2 of A study of the proficiency and performance of Iranian Air Traffic Controllers: attitude, work experience and specific aviation English courses
Creators: name: Rahmati, Massoud
name: Izadpanah, Siros
Publisher: name: figshare
Year: 2021
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2. Model Fit Summary.
Does private money increase party extremism?
Creators: name: Tomashevskiy, Andrey
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: In this paper, I explore whether private money affects party extremism. This is one of the most important questions in the study of party politics, but it has not been systematically studied in the comparative context due to lack of data. I have assembled a novel and most comprehensive cross-national data about private donations that are currently available. Using these data that cover 45 parties in 9 countries from 1996 to 2013, I show that the more private money parties receive, the more likely are they to take extreme positions. I further show that this effect is especially strong in the case of the more ideological, principled issues, and absent in the case of the less ideological, pragmatic ones. These findings contribute to our understanding of party position taking and the role of money in politics.
Microservices-based Business Process Model Automation
Creators: name: Koschmider, Agnes
Publisher: name: Karlsruhe
Year: 2017
Subjects: Microservices
business process automation
business process execution

description: Recently, microservices evolved as a new software architecture paradigm allowing to build independently deployable software systems. In the context of Business Process Management microservices could be used to automate the execution of highly distributed business process models as required within the digital transformation. This paper sketches a microservices-based business process model execution and discusses challenges.
The impact of translation control of protein synthesis on neuroblastoma and medulloblastoma progression
Creators: name: Delaidelli, Alberto
Publisher: name: University of British Columbia
Year: 2023

description: Neuroblastoma and medulloblastoma, malignant tumors of the nervous system, are the most common childhood solid tumors and leading cause of childhood related cancer deaths. A subset of these tumors, collectively characterized by MYC of MYCN amplification or overexpression, bears dismal prognosis with a ten-year survival rate around 50%. However, the discovery of molecularly informed targeted therapies represents a major challenge in current cancer research, and these are currently unavailable for children affected by neuroblastoma and medulloblastoma. It is sobering that for most children who suffer relapse, there are few if any therapeutic options available, with most patients receiving the same type of therapy that failed in the first place. While MYC-driven oncogenic transformation is known to determine adverse patient outcome, it also induces a high metabolic demand that impairs cell survival under acute nutrient deprivation (ND). We previously reported that eukaryotic Elongation Factor Kinase 2 (eEF2K), the master regulator of mRNA translation elongation, is critical for cell adaptation to ND. We therefore set out to determine if eEF2K is required for the progression of MYC-driven childhood cancer. Our in vitro and in vivo results revealed that MYCN and MYC driven neuroblastoma and medulloblastoma rely on eEF2K to overcome nutrient starvation. We surveyed clinical samples of neuroblastoma and medulloblastoma, and we observed high eEF2K activity to be significantly associated with MYC family members overexpression. Mechanistically, through multiple proteomics experiments coupled with RNAseq, we found that eEF2K regulates the synthesis of several components of the mitochondrial electron transport chain. As a result, eEF2K deficient cells displayed inefficient super complex assembly and oxidative phosphorylation. Overall, our work identifies novel targetable pathways contributing to the progression of MYC driven neuronal tumors. Future studies should investigate the combination of eEF2K inhibition with caloric restriction mimetics, as a targeted therapeutic approach for MYC driven tumors.
Covariant Fields of C*-Algebras under Rieffel Deformation
Creators: name: Belmonte, Fabian
name: Mantoiu, Marius
Publisher: name: arXiv
Year: 2011
Subjects: subject: Operator Algebras (math.OA)
subject: Spectral Theory (math.SP)
subject: FOS: Mathematics
subject: 35S05, 81Q10, 46L55, 47C15

description: We show that Rieffel's deformation sends covariant C(T)-algebras into C(T)-algebras. We also treat the lower semi-continuity issue, proving that Rieffel's deformation transforms covariant continuous fields of C*-algebras into continuous fields of C*-algebras. Some examples are indicated, including certain quantum groups.
Additional file 1 of General practitioner practice-based pharmacist input to medicines optimisation in the UK: pragmatic, multicenter, randomised, controlled trial
Creators: name: Syafhan, Nadia Farhanah
name: Azzam, Sayer Al
name: Williams, Steven D.
name: Wilson, Wendy
name: Brady, Jayne
name: Lawrence, Peter
name: McCrudden, Mark
name: Ahmed, Mustafa
name: Scott, Michael G.
name: Fleming, Glenda
name: Hogg, Anita
name: Scullin, Claire
name: Horne, Robert
name: Harblas Ahir
name: McElnay, James C.
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Biotechnology
Cancer
Science Policy
Computational Biology

description: Additional file 1. Unit costs (£) used in healthcare resource utilisation calculations.
On the origin of extremely high strength of ultrafine-grained Al alloys produced by severe plastic deformation
Creators: name: Valiev, Ruslan
name: Enikeev, Nariman
name: Murashkin, Maxim
name: Kazykhanov, V.
name: Sauvage, Xavier
Publisher: name: arXiv
Year: 2010
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Ultrafine-grained Al alloys produced by high pressure torsion are found to exhibit a very high strength, considerably exceeding the Hall-Petch predictions for the ultrafine grains. The phenomena can be attributed to the unique combination of ultrafine structure and deformation-induced segregations of solute elements along grain boundaries, which may affect the emission and mobility of intragranular dislocations.
The Surprising Transparency of the sQGP at LHC
Creators: name: Horowitz, W. A.
name: Gyulassy, Miklos
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We present parameter-free predictions of the nuclear modification factor, R_{AA}^pi(p_T,s), of high p_T pions produced in Pb+Pb collisions at sqrt{s}_{NN}=2.76 and 5.5 ATeV based on the WHDG/DGLV (radiative+elastic+geometric fluctuation) jet energy loss model. The initial quark gluon plasma (QGP) density at LHC is constrained from a rigorous statistical analysis of PHENIX/RHIC pi^0 quenching data at sqrt{s}_{NN}=0.2 ATeV and the charged particle multiplicity at ALICE/LHC at 2.76 ATeV. Our perturbative QCD tomographic theory predicts significant differences between jet quenching at RHIC and LHC energies, which are qualitatively consistent with the p_T-dependence and normalization---within the large systematic uncertainty---of the first charged hadron nuclear modification factor, R^{ch}_{AA}, data measured by ALICE. However, our constrained prediction of the central to peripheral pion modification, R^pi_{cp}(p_T), for which large systematic uncertainties associated with unmeasured p+p reference data cancel, is found to be over-quenched relative to the charged hadron ALICE R^{ch}_{cp} data in the range 5
description: 13 pages, 8 figures
Tree-valued Fleming-Viot dynamics with mutation and selection
Creators: name: Depperschmidt, Andrej
name: Greven, Andreas
name: Pfaffelhuber, Peter
Publisher: name: arXiv
Year: 2011
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: The Fleming-Viot measure-valued diffusion is a Markov process describing the evolution of (allelic) types under mutation, selection and random reproduction. We enrich this process by genealogical relations of individuals so that the random type distribution as well as the genealogical distances in the population evolve stochastically. The state space of this tree-valued enrichment of the Fleming-Viot dynamics with mutation and selection (TFVMS) consists of marked ultrametric measure spaces, equipped with the marked Gromov-weak topology and a suitable notion of polynomials as a separating algebra of test functions. The construction and study of the TFVMS is based on a well-posed martingale problem. For existence, we use approximating finite population models, the tree-valued Moran models, while uniqueness follows from duality to a function-valued process. Path properties of the resulting process carry over from the neutral case due to absolute continuity, given by a new Girsanov-type theorem on marked metric measure spaces. To study the long-time behavior of the process, we use a duality based on ideas from Dawson and Greven [On the effects of migration in spatial Fleming-Viot models with selection and mutation (2011c) Unpublished manuscript] and prove ergodicity of the TFVMS if the Fleming-Viot measure-valued diffusion is ergodic. As a further application, we consider the case of two allelic types and additive selection. For small selection strength, we give an expansion of the Laplace transform of genealogical distances in equilibrium, which is a first step in showing that distances are shorter in the selective case.
description: Published in at http://dx.doi.org/10.1214/11-AAP831 the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org)