cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identification of ALYREF in pan cancer as a novel cancer prognostic biomarker and potential regulatory mechanism in gastric cancer
Creators: name: Yuan, Yujie
name: Fan, Hong
name: Sun, Jinghan
name: Fan, Yiyang
name: Sun, Hui
name: Tang, Wenqing
name: Su, Hongmeng
Publisher: name: Springer Nature
Year: 2024

description: ALYREF is considered as a specific mRNA m5C-binding protein which recognizes m5C sites in RNA and facilitates the export of RNA from the nucleus to the cytoplasm. Expressed in various tissues and highly involved in the transcriptional regulation, ALYREF has the potential to become a novel diagnostic marker and therapeutic target for cancer patients. However, few studies focused on its function during carcinogenesis and progress. In order to explore the role of ALYREF on tumorigenesis, TCGA and GTEx databases were used to investigate the relationship of ALYREF to pan-cancer. We found that ALYREF was highly expressed in majority of cancer types and that elevated expression level was positively associated with poor prognosis in many cancers. GO and KEGG analysis showed that ALYREF to be essential in regulating the cell cycle and gene mismatch repair in tumor progression. The correlation analysis of tumor heterogeneity indicated that ALYREF could be specially correlated to the tumor stemness in stomach adenocarcinoma (STAD). Furthermore, we investigate the potential function of ALYREF on gastric carcinogenesis. Prognostic analysis of different molecular subtypes of gastric cancer (GC) unfolded that high ALYREF expression leads to poor prognosis in certain subtypes of GC. Finally, enrichment analysis revealed that ALYREF-related genes possess the function of regulating cell cycle and apoptosis that cause further influences in GC tumor progression. For further verification, we knocked down the expression of ALYREF by siRNA in GC cell line AGS. Knockdown of ALYREF distinctly contributed to inhibition of GC cell proliferation. Moreover, it is observed that knocked-down of ALYREF induced AGS cells arrested in G1 phase and increased cell apoptosis. Our findings highlighted the essential function of ALYREF in tumorigenesis and revealed the specific contribution of ALYREF to gastric carcinogenesis through pan-cancer analysis and biological experiments.
Additional file 3 of N/OFQ modulates orofacial pain induced by tooth movement through CGRP-dependent pathways
Creators: name: Yan, Xinyu
name: Han, Han
name: Zhang, Shizhen
name: Lu, Yanzhu
name: Ren, Linghuan
name: Tang, Yufei
name: Li, Xiaolong
name: Jian, Fan
name: Wang, Yan
name: Long, Hu
name: Lai, Wenli
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 3: Figure S1. Full results of Western blot analysis for the quantification of N/OFQ expression in trigeminal ganglia. Figure S2. Full results of Western blot analysis of CGRP expression in trigeminal ganglion of rats in NS group, N/OFQ group and UFP-101 group. Figure S3. Full results of Western blot analysis of N/OFQ expression in trigeminal ganglion of rats in NS group, control lentivirus group and PNOC lentivirus group.
Das Handschriftenportal. Präsentation und experimentelle Exploration | Erste Eventtage
Creators: name: Schaßan, Torsten
name: Hahn, Carolin
Publisher: name: Zenodo
Year: 2021
Subjects: Handschriftenportal
Handschriften
Manuscripts
Digital Humanities
TEI
XML
Usability
User Interface

description: Die Präsentation wurde auf den "Ersten Eventtagen" der vDHd 2021 gehalten. Sie bildete den Rahmen für folgende Workshops: „Oberfläche für handschriftenbezogene Informationen“, mit Carolin Hahn, Torsten Schaßan, Leander Seige: Dienstag, 23.03.2021, 13–14 Uhr „Daten für handschriftenbezogene Informationen“, mit Torsten Schaßan, Leander Seige: Mittwoch, 24.03.2021, 9–10 Uhr „Schnittstellen für handschriftenbezogene Informationen“, mit Torsten Schaßan: Donnerstag, 25.03.2021, 13–14 Uhr
Continuous-wave squeezed states of light via 'up-down' self-phase modulation
Creators: name: Singh, Amrit Pal
name: Ast, Stefan
name: Mehmet, Moritz
name: Vahlbruch, Henning
name: Schnabel, Roman
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Continuous-wave (cw) squeezed states of light have applications in sensing, metrology and secure communication. In recent decades their efficient generation has been based on parametric down-conversion, which requires pumping by externally generated pump light of twice the optical frequency. Currently, there is immense effort in miniaturizing squeezed-light sources for chip-integration. Designs that require just a single input wavelength are favored since they offer an easier realization. Here we report the first observation of cw squeezed states generated by self-phase modulation caused by subsequent up and down conversions. The wavelengths of input light and of balanced homodyne detection are identical, and 1550 nm in our case. At sideband frequencies around 1.075 GHz, a nonclassical noise reduction of (2.4 +/- 0.1) dB is observed. The setup uses a second-order nonlinear crystal, but no externally generated light of twice the frequency. Our experiment is not miniaturized, but might open a route towards simplified chip-integrated realizations.
On the Effect of Rainfall Variations on Economic Variables: The Application of General Equilibrium Model
Creators: name: Moinoddini, Zeinab
name: Mohammadi, Hamid
name: Akhlagh, Rahman Khosh
name: Boshrabadi, Hossein Mehrabi
name: Moinoddini, Zeinab
name: Mohammadi, Hamid
name: Akhlagh, Rahman Khosh
name: Boshrabadi, Hossein Mehrabi
Publisher: name: Unknown
Year: 2018
Subjects: subject: Environmental Economics and Policy
subject: agricultural sector
subject: economics variables
subject: general equilibrium model
subject: rainfall

description: The economy of Iran is dependent on many variables that play a role in its growth and development. On the other hand, rainfall is one of the important factors of climate change that has affected economic strategic programs including those of the agricultural sector. Rainfall variations impact many economic variables, some of which are explored here. The aim of this study was to evaluate rainfall shocks on some economic variables using a general equilibrium model that included the best scenario representing the highest rainfall, the worst scenario representing the lowest rainfall, and normal scenario considering average rainfall. To check the effect of these changes on the agricultural sector, a set of commodities produced by this section is considered separately, and other sections are considered in general. The results showed that the production of these commodities has been increased by about 14% in the best rainfall scenario. All commodities have been faced with reduced consumption from 0.3% to 10.3% in the worst rainfall scenario; this was the greatest loss of products related to the agricultural commodities. Rainfall increased the price of all commodities by 0.25-28.7%, except for industry. Both private and public investments were influenced by rainfall change.
title: Nonea lutea (Desr.) DC. in Lam. & DC.
Creators: name: :None
Publisher: name: Universitätsbibliothek
Year: 2011
Subjects: subject: Digitale Pflanzenbilder: Sammlung Dietmar Brandes
subject: 580

description: Digitale Pflanzenbilder: Sammlung Dietmar Brandes
Influencing Factors on Adoption of Organic Farming from the Perspective of Horticulturists in Sari County, Iran
Creators: name: Dinpanah, Reza
name: Dinpanah, Reza
Publisher: name: Unknown
Year: 2018
Subjects: subject: Crop Production/Industries
subject: Farm Management
subject: adoption
subject: organic farming
subject: horticulturist

description: The economy of Iran is dependent on many variables that play a role in its growth and development. On the other hand, rainfall is one of the important factors of climate change that has affected economic strategic programs including those of the agricultural sector. Rainfall variations impact many economic variables, some of which are explored here. The aim of this study was to evaluate rainfall shocks on some economic variables using a general equilibrium model that included the best scenario representing the highest rainfall, the worst scenario representing the lowest rainfall, and normal scenario considering average rainfall. To check the effect of these changes on the agricultural sector, a set of commodities produced by this section is considered separately, and other sections are considered in general. The results showed that the production of these commodities has been increased by about 14% in the best rainfall scenario. All commodities have been faced with reduced consumption from 0.3% to 10.3% in the worst rainfall scenario; this was the greatest loss of products related to the agricultural commodities. Rainfall increased the price of all commodities by 0.25-28.7%, except for industry. Both private and public investments were influenced by rainfall change.
Fa ctors Affecting Farmer's Satisfaction with Water Users Associations Performance at Gotvand Irrigation Scheme in Khuzestan Province, Iran
Creators: name: Karami, Ayatollah
name: Choghakhor, Hamid Yeilagh
name: Karami, Ayatollah
name: Choghakhor, Hamid Yeilagh
Publisher: name: Unknown
Year: 2018
Subjects: subject: Resource /Energy Economics and Policy
subject: Gotvand irrigation scheme
subject: Water Users Association (WUA)
subject: satisfaction
subject: Iran

description: The purpose of this study was to assess the farmer's satisfaction with services delivered by Water User Associations (WUAs) and determine the factors affecting farmer's satisfaction with the WUAs. Stratified sampling was used to select 124 farmer members of WUAs in the Gotvand irrigation Scheme (GIS). A researcher-made questionnaire was employed for data collection. Its validity was confirmed by content validity and its total reliability was estimated by Cronbach's alpha as to be 0.73. Data were analyzed using descriptive statistics to describe WUAs performance; ordinal logistic regression was also used to determine the relationship between physical, socio-economic characteristics of region context and farmer's satisfaction. Results revealed that although the WUAs performance in operation, maintenance and repair and management is medium, these WUAs are successful in collection of irrigation service fee. Status of maintenance and repair in GIS is a very essential factor in farmer satisfaction with the WUAs and its status is dependent on the strength of WUA connection with government authorities. Therefore, it is recommended that maintenance and repair management is transferred to the WUAs.
Generalizations of entanglement based on coherent states and convex sets
Creators: name: Barnum, H.
name: Knill, E.
name: Ortiz, G.
name: Viola, L.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Physics (quant-ph)
subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: Unentangled pure states on a bipartite system are exactly the coherent states with respect to the group of local transformations. What aspects of the study of entanglement are applicable to generalized coherent states? Conversely, what can be learned about entanglement from the well-studied theory of coherent states? With these questions in mind, we characterize unentangled pure states as extremal states when considered as linear functionals on the local Lie algebra. As a result, a relativized notion of purity emerges, showing that there is a close relationship between purity, coherence and (non-)entanglement. To a large extent, these concepts can be defined and studied in the even more general setting of convex cones of states. Based on the idea that entanglement is relative, we suggest considering these notions in the context of partially ordered families of Lie algebras or convex cones, such as those that arise naturally for multipartite systems. The study of entanglement includes notions of local operations and, for information-theoretic purposes, entanglement measures and ways of scaling systems to enable asymptotic developments. We propose ways in which these may be generalized to the Lie-algebraic setting, and to a lesser extent to the convex-cones setting. One of our original motivations for this program is to understand the role of entanglement-like concepts in condensed matter. We discuss how our work provides tools for analyzing the correlations involved in quantum phase transitions and other aspects of condensed-matter systems.
description: 37 pages
Evolution and extinction dynamics in rugged fitness landscapes
Creators: name: Sibani, Paolo
name: Brandt, Michael
name: Alstroem, Preben
Publisher: name: arXiv
Year: 1997
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Quantitative Biology (q-bio)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Macroevolution is considered as a problem of stochastic dynamics in a system with many competing agents. Evolutionary events (speciations and extinctions) are triggered by fitness records found by random exploration of the agents' fitness landscapes. As a consequence, the average fitness in the system increases logarithmically with time, while the rate of extinction steadily decreases. This dynamics is studied by numerical simulations and, in a simpler mean field version, analytically. We also study the effect of externally added `mass' extinctions. The predictions for various quantities of paleontological interest (life-time distributions, distribution of event sizes and behavior of the rate of extinction) are robust and in good agreement with available data. Brief version of parts of this work have been published as Letters. (PRL 75, 2055, (1995) and PRL, 79, 1413, (1997))
description: 30 pages 9 figures LaTeX
АНАЛИЗ СУЩЕСТВУЮЩИХ КОНСТРУКТИВНЫХ РЕШЕНИЙ УСТРОЙСТВА ДЕФОРМАЦИОНННЫХ ШВОВ
Creators: name: НЕМЧИКОВА ЛАРИСА АЛЕКСАНДРОВНА
name: РУБЕЛЬ ЕКАТЕРИНА ВЯЧЕСЛАВОВНА
Publisher: name: Colloquium-journal
Year: 2019
Subjects: ДЕФОРМАЦИОННЫЙ ШОВ
КОМПЕНСАТОРНЫЙ ШОВ
УСАДОЧНЫЙ ШОВ
DEFORMATIONAL SEAM
EXPANSION JOINT
COMPENSATORY SEAM
SHRINK SEAM

description: Рассмотрены достоинства и недостатки существующих проектных решений устройства деформационных швов.
A ring-of-fire in the pulsar magnetosphere
Creators: name: Contopoulos, Ioannis
name: Stefanou, Petros
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Contopoulos 2019 proposed that a dissipation zone develops in the magnetosphere of young pulsars at the edge of the closed-line region beyond the light cylinder. This is necessary in order to supply the charge carriers that will establish current closure through the equatorial and separatrix current-sheets. In the present work, we propose to investigate in greater detail this region with a simplified model that we would like to call the `ring-of-fire'. According to this simple model, the dissipation zone is a narrow reconnection layer where electrons and positrons are accelerated inwards and outwards respectively along Speiser orbits that are deflected in the azimuthal direction by the pulsar rotation. After they exit the reconnection layer, the accelerated positrons form the positively charged equatorial current-sheet, and the accelerated electrons form the negatively charged separatrix current-sheet along the boundary of the closed-line region. During their acceleration, particles lose only a small part of their energy to radiation. Most of their energy is lost outside the dissipation region, in the equatorial and separatrix current sheets. Our simple model allows us to obtain high-energy spectra and efficiencies. The radiation emitted by the positrons in the equatorial current-sheet forms a very-high energy tail that extends up to the TeV range.
description: 9 pages, 6 figures, Monthly Notices
Additional file 1: of Cognitive assessment of idiopathic intracranial hypertension patients
Creators: name: Elbanhawy, Iman
name: Gihan Ramzy
name: Ashour, Amal
name: Khedr, Diana
Publisher: name: figshare
Year: 2019
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Appendix 1. Neurology sheet. (DOCX 20 kb)
Progressive reclamation at the Kemess South Mine : “doing what comes naturally"
Creators: name: Davidson, Scott Charles
name: Stogran, S. Wade
Publisher: name: The University of British Columbia
Year: 2009

description: The progressive reclamation program at the Kemess Mine focuses on the reclamation of disturbed areas using a successional approach to revegetation. The aim of the successional approach is to reduce the time required to develop a self-sustaining vegetative cover through the use of plant species that are found naturally in the area of the minesite. Research into native species is being conducted at the site as part of the annual reclamation program to allow for refinement of the reclamation program.
Additional file 1: of Diversity of Bacillus cereus sensu lato mobilome
Creators: name: Fayad, Nancy
name: Awad, Mireille Kallassy
name: Mahillon, Jacques
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 60506 Virology

description: Table S1A. Accession numbers of the analyzed B. cereus s.l. replicons. B. thuringiensis cry- and B. cereus s.s. cry+ are placed under B. thuringiensis-like. Table S1B. Genomic details of eight B. thuringiensis cry- and four B. cereus s.s. cryâ +Â Table S2. Heat map of the total bcr number in the complete genomes of nine B. cereus s.l. species. The heat map is arranged by species and decreasing bcr1 occurrence. Table S3A. Correlation pairs for the 102 analyzed B. cereus s.l. genomes. Table S3B. Correlation pairs for the 102 analyzed B. cereus s.l. genomes by species. Table S4A. Heat map and distribution of group II intron types in the complete genomes of 9 B. cereus sensu lato species. Table S4B. Heat map and distribution of group II introns in the complete genomes of 9 B. cereus sensu lato species. (DOCX 1276 kb)
Atom ionization by ultrashort laser pulse - 2D, 3D consideration
Creators: name: Larionov, Nikolay V.
name: Makarov, Dmitry N.
name: Smirnovsky, Alexander A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Optics (physics.optics)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We theoretically analyze the quantum vortices - the zeros of electron wave function which are formed through atom ionization by ultrashort laser pulse. In 2D space we consider the case of above-threshold ionization of hydrogen atom and in 3D space the ionization of the atom in the zero-radius-potential approximation. With the help of obtained analytical results we make the assumption that localization of quantum vortices in 3D space can be predicted by analysis of 2D model.
Characterizing Hilbert space frames with the subframe property
Creators: name: Casazza, Peter G.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 46C05; 46B03; 46N99

description: We characterize Riesz frames and frames with the subframe property and use this to answer most of the questions from the literature concerning these properties and their relationships to the projection methods etc.
Multiscale Analysis of Reinforced Concrete Structures
Creators: Moyeda Morales, Arturo
Publisher: name: Columbia University
Year: 2018
Subjects: subject: Civil engineering
subject: FOS: Civil engineering
subject: Multiscale modeling
subject: Reinforced concrete--Analysis
subject: Structural analysis (Engineering)

description: A multiscale approach, coined as the High Order Computational Continua (HC2), has been developed for efficient and accurate analysis and design of reinforced concrete structures. Unlike existing homogenization-like methods, the proposed multiscale approach is capable of handling large representative volume elements (RVE), i.e., the classical assumption of infinitesimally is no longer required, while possessing accuracy of direct numerical simulation (DNS) and the computational efficiency of classical homogenization methods.
      The multiscale beam and plate elements formulated using the proposed HC2 methodology can be easily incorporated into the existing reinforced concrete design practices. The salient features of the proposed formulation are: (i) the ability to consider large representative volume elements (RVE) characteristic to nonsolid beams,waffle and hollowcore slabs, (ii) versatility stemming from the ease of handling damage, prestressing, creep and shrinkage, and (iii) computational efficiency resulting from model reduction, combined with the damage law rescaling methods that yield simulation results nearly mesh-size independent.
      The multiscale formulation has been validated against experimental data for rectangular beams, I beams, pretensioned beams, continuous posttension beams, solid slabs, prestressed hollowcore slabs and waffle slabs.
Additional file 1 of T2 mapping and fat quantification of lumbar paraspinal muscle in ankylosing spondylitis: a case control study
Creators: name: Huang, Ruibin
name: Yang, Hongwu
name: Chen, Liujiang
name: Su, Shuyan
name: Wu, Xiaojia
name: Zhuang, Ruyao
name: Liu, Yuan
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Sociology
subject: FOS: Sociology

description: Additional file 1: Supplementary Table 1. Correlation between CSA, FF, and T2 relaxation time in AS.
Perceptions of X+Y Scheduling Among Combined Internal Medicine-Pediatrics Residency Trainees: A Qualitative Program Evaluation
Creators: name: Stehouwer, Nathan R
name: Spangler, Hillary
name: Contarino, Michael
name: Szalda, Dava
name: Patel, Bhavesh
name: Nadamuni, Mridula
name: Diamond-Falk, Kathryn
name: Walsh, Jennifer B
Publisher: name: Springer Nature
Year: 2024

description: OBJECTIVE: The study aims to elicit perceived benefits and downsides of X+Y scheduling for combined Internal Medicine-Pediatrics (Med-Peds) residents via focus groups.
METHODS: Five focus groups were conducted with Med-Peds residents in participating programs which utilized X+Y scheduling. Onefocus group was held per participating institution. Each focus group was facilitated by a chief resident from a different participating institution. Questions were developed by the study team after a review of the literature and local experience with X+Y scheduling and included open-ended questions. Focus groups were recorded and transcribed. Transcripts were reviewed by study team members, and representative themes and quotes were presented. The main outcome was to evaluate the perceived benefits and downsides of X+Y scheduling for Med-Peds.
RESULTS: Results from four of the five focus groups were fully reviewed. Themes regarding the benefits of X+Y scheduling included (1) improved inpatient and outpatient experience, (2) predictability in schedule which improved wellness, and (3) longitudinal time for career exploration. Downsides of X+Y scheduling were highlighted as well including (1) condensing too many experiences into Y time and (2) challenges that exist when categorical medicine and pediatrics programs use different block schedules.
CONCLUSIONS: X+Y schedules create potential solutions for longstanding barriers to medical education and notably conflict with inpatient and outpatient responsibilities. Our data shows similar benefits to X+Y scheduling for combined residents as for their categorical colleagues and sheds light on some unique considerations for combined programs and trainees. Additional studies should continue to assess the effect of X+Y scheduling on our combined trainees.
Minimal Yukawa deflection of AMSB from the Kahler potential
Creators: name: Li, Zhuang
name: Wang, Fei
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose a minimal Yukawa deflection scenario of AMSB from the Kahler potential through the Higgs-messenger mixing. Salient features of this scenario are discussed and realistic MSSM spectrum can be obtained. Such a scenario, which are very predictive, can solve the tachyonic slepton problem with less messenger species. Numerical results indicate that the LOSPs predicted by this scenario can not be good DM candidates. So it is desirable to extend this scenario with a Peccei-Quinn sector to solve the strong CP problem and at the same time provide new DM candidates. We propose a way to obtain a light axino mass in SUSY KSVZ axion model with Yukawa deflected anomaly mediation SUSY breaking mechanism. The axino can possibly be the LSP and act as a good DM candidate.
description: Minor changes, published version. 25 pages, 6 figures
Scaling behavior of Ising systems at first-order transitions
Creators: name: Fontana, Pierpaolo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We investigate how the scaling behavior of finite systems at magnetic first-order transitions (FOTs) with relaxational dynamics changes in correspondence of various boundary conditions. As a theoretical laboratory we consider the two-dimensional Ising model in the low-temperature phase. When the boundary conditions do not favor any specific phase of the system, we show that a dynamic finite-size scaling (DFSS) theory can be developed to describe the dynamic behavior in the coexistence region, where different phases coexist. When the boundary conditions at two opposite sides of the system generate a planar interface separating the phases, we show that the autocorrelation times are characterized by a power-law behavior, related to the dynamics enforced by the interface. Numerical results for a purely relaxational dynamics confirm the general picture.
description: 18 pages, 8 figures
Adaptación de la Escala de estigma internalizado relacionado con el VIH
Creators: name: CUBAS ROMERO, TANITH LIZETH
name: VELARDE-CAMAQUI, DAVIS
name: COPAJA-HERNÁNDEZ, LUZ
name: OJEDA SIGUAS, ROBERT CHRISTIAN
name: VARELA GUEVARA, SILVANA GRACIELA
Publisher: name: Zenodo
Year: 2024

description: This scale is an adaptation from the Thai Internalized HIV-Related Stigma Scale by Uthis et al. (2023)
РЕГУЛИРОВАНИЕ ВОДНО-ТЕПЛОВОГО РЕЖИМА ЗЕМЛЯНОГО ПОЛОТНА АВТОДОРОГ НА УЧАСТКАХ С ВЫСОКИМ УРОВНЕМ ГРУНТОВЫХ ВОД
Creators: name: СЕЛИВЕРСТОВА О.В.
Publisher: name: Colloquium-journal
Year: 2019
Subjects: ЗЕМЛЯНОЕ ПОЛОТНО
ГРУНТОВЫЕ ВОДЫ
РЕГУЛИРОВАНИЕ ВОДНО ТЕПЛОВОГО РЕЖИМА
ДЕФОРМАЦИИ ЗЕМЛЯНОГО ПОЛОТНА
ПУЧИНЫ
SUBGRADE
GROUNDWATER
REGULATION OF WATER THERMAL CONDITIONS
ROADBED DEFORMATION
FROST HEAVING

description: В статье рассматривается вопрос регулирования водно-теплового режима земляного полотна автомобильной дороги с целью обеспечения и поддержания их транспортно-эксплуатационного состояния. Предлагаются решения по устранениюпроблем, выявленных впроцессе эксплуатации.
Multiscale Modeling and Microfluidic Study of Particle-Laden Emulsions and Foams
Creators: Das, Subhabrata
Publisher: name: Columbia University
Year: 2019
Subjects: subject: Chemical engineering
subject: FOS: Chemical engineering
subject: Mathematics
subject: FOS: Mathematics
subject: Mechanics
subject: Emulsions
subject: Foam
subject: Microfluidics

description: The aim of this thesis is to gain new insights into the physics underlying the long-term stability and instability of liquid foams and emulsions in the absence and presence of particles. By using Finite element based and mesoscopic Lattice Boltzmann techniques along with the microfluidic tools at our disposal, we tackled this question using two very different, yet complementary, approaches. In the first part, we went down to the smallest scale of foam, by observing a single bubble where the particle would straddle at interfaces of thin films. This brought a novel understanding to the observation that the torque on the particle is independent of film thickness and was mainly contributed by contact line stresses. We then precisely measured the hydrodynamic and dielectrophoretic interactions of a particle armored bubble treating the bubble as a flat surface and showed that its resistance to the motion was much less for hydrophobic particles compared to other wetting particles while the dielectrophoretic forces were more for hydrophobic particles as the latter protruded more in the oil phase. These findings are of utmost importance when designing particle-stabilized foams and dielectrophoresis-based particle separation techniques because they guide the choice of the particles to use for a particular application. In the second part, we studied the foam at a larger scale, by analyzing the evolution of a large population of identical bubbles produced in microfluidic geometries. This monodisperse foam destabilizes through Ostwald ripening or Coarsening toward a well-known self-similar state. However, we have shown that the transient regime leading to that state is not homogeneous in space. The microfluidic model that we develop predicts how the disorder grows in the foam, which is a valuable asset in applications where an ordered organization of the bubbles is required resisting foam coarsening. Furthermore, multiscale Lattice Boltzmann simulations of emulsion drainage based on frustrated long-range interactions are developed using the images from the microfluidic experiment as the initial phase thus providing a global understanding of emulsion stabilization and drainage dynamics. The key parameters investigated for particle-induced emulsion stabilization were solid particle concentration, particle size, wettability, heterogeneity and particle shape. The resulting emulsion droplets adopted pronounced non-spherical polyhedral shapes with time, indicating a high elasticity of the interface. The stability and the remarkable non-spherical shape of the emulsion droplets stabilized by the particles were features which bear resemblance with foam stabilization of bubbles using hydrophobic particles in flotation processes.
Further Excavations in Lewes, 1975
Creators: name: Freke, D
Publisher: name: Archaeology Data Service
Year: 2021

description: Sussex Archaeological Collections, 114, 176-193
description: Following the excavations in Brook Street and Lancaster Street in 1974, the opportunity was taken to check the northern extent of the medieval town on a site in North Street. Permission to excavate was kindly granted by Lewes District Council in advance of an extensive building scheme. The work was carried out by the Sussex Archaeological Field Unit, with a grant from the Department of the Environment, under the direction of the author. The finds are deposited at Barbican House, Lewes, and the detailed plans and notes are in the files of the Sussex Archaeological Field Unit.
Self-Organized Criticality with Complex Scaling Exponents in the Train Model
Creators: name: Elmer, Franz-Josef
Publisher: name: arXiv
Year: 1997
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences

description: The train model which is a variant of the Burridge-Knopoff earthquake model is investigated for a velocity-strengthening friction law. It shows self-organized criticality with complex scaling exponents. That is, the probability density function of the avalanche strength is a power law times a log-periodic function. Exact results (scaling exponent: $3/2+2πi/\ln 4$) are found for a nonlocal cellular automaton which approximates the overdamped train model. Further the influence of random static friction is discussed.
description: Written in RevTeX, 4 pages, 5 PostScript figure, appears in PRE
Isothermal spherical perfect fluid model: Uniqueness and Conformal mapping
Creators: name: Dadhich, Naresh
Publisher: name: arXiv
Year: 1996
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We prove the theorem: The necessary and sufficient condition for a spherically symmetric spacetime to represent an isothermal perfect fluid (barotropic equation of state with density falling off as inverse square of the curvature radius) distribution without boundary is that it is conformal to the ``minimally'' curved (gravitation only manifesting in tidal acceleration and being absent in particle trajectory) spacetime.
description: 7 pages, TeX version
Conceptual reclamation planning and the development of results-based standards at Elk Valley Coal’s Elkview Operations
Creators: name: Przeczek, John
name: Ryder, Dave
Publisher: name: The University of British Columbia
Year: 2009

description: In the winter of 2002/2003 Elk Valley Coal, Elkview Operations updated the 20-year reclamation plan that was prepared in 1983 when the mine was operated by Westar Mining Ltd. The resulting conceptual reclamation plan provides a vision for the horizontal distribution, vertical structure, and species composition of the plant communities that will be established. Clear, measurable and objective results-based standards for assessing reclamation success were developed and incorporated into the plan. Implementation of the conceptual reclamation plan will ensure that end land use and reclamation objectives are achieved, reclamation activities are progressive, and that the reclamation program remains flexible and responsive to new ideas and information.
Additional file 1: of Concordance of the point-of-care circulating cathodic antigen test for the diagnosis of intestinal schistosomiasis in a low endemicity area
Creators: name: Sousa, Sergei
name: Dias, Isabelle
name: Fonseca, Álvaro
name: Contente, Bianca
name: Nogueira, Joyce
name: Tatyellen Costa Oliveira
name: Geiger, Stefan
name: Enk, Martin
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology

description: Multilingual abstracts in the five official working languages of the United Nations. (PDF 560 kb)
Multiscale Mechanobiology of Primary Cilia
Creators: Nguyen, An My
Publisher: name: Columbia University
Year: 2015
Subjects: Cilia and ciliary motion
Mechanoreceptors
Biomedical engineering
Biomechanics
Cytology

description: Mechanosensation, the ability for cells to sense and respond to physical cues, is a ubiquitous process among living organisms and its dysfunction can lead to devastating diseases, including atherosclerosis, osteoporosis, and cancer. The primary cilium is a solitary, immotile organelle that projects from the surface of virtually every cell in the human body and can function as a mechanosensor across diverse biological contexts, deflecting in response to fluid flow, pressure, touch and vibration. It can detect urinary flow rate in the kidney, monitor bile flow in the liver, and distinguish the direction of nodal flow in embryos. In this thesis, we examined the interplay of biology and mechanics in the context of this multifunctional sensory organelle from the tissue to subcellular scale.
      In the first part of this work, we examined the cilium at the tissue level. Primary cilia are just beginning to be appreciated in bone with studies recently reporting loss of cilia results in defects in skeletal development and adaptation. We disrupted primary cilia in osteocytes, the principal mechanosensing cells in bone, and demonstrated that loss of primary cilia in osteocytes impairs load-induced bone formation. Over the course of our work with primary cilia, we also identified the need for more standardized imaging approaches to the cilium and presented an improvement to distinguishing proteins within the cilium from the rest of the cell.
      In the later part of this work, we examined the primary cilium at the subcellular level. While deflection is integral to the cilium's mechanosensory function, it remains poorly understood and characterized. Using a novel experimental and computational approach to capture and determine the mechanical properties of the cilium, we demonstrated cilium deflection can be mechanically and chemically modulated. We revealed a mechanism, acetylation, through which this mechanosensor can adapt and regulate overall cellular mechanosensing. By modifying our combined experimental and computational approach, we analyzed cilium deflection in vivo for the first time.
      Collectively, this work uncovers new insights across biological scales in the primary cilium as an extracellular nexus integrating mechanical stimuli and cellular signaling. Understanding the mechanisms driving cilium mechanosensing has broad reaching implications and unlocks the cilium's potential as a therapeutic target to treat impaired cellular mechanosensing critical to a multitude of diseases.
title: Nothofagus dombeyi (Mirb.) Oerst.
Creators: name: :None
Publisher: name: Universitätsbibliothek
Year: 2011
Subjects: subject: Digitale Pflanzenbilder: Sammlung Dietmar Brandes
subject: 580

description: Pflanzensammlung Dietmar Brandes: Digitale Pflanzenbilder
Evidence of short time dynamical correlations in simple liquids
Creators: name: Scopigno, T.
name: Ruocco, G.
name: Sette, F.
name: Viliani, G.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We report a molecular dynamics (MD) study of the collective dynamics of a simple monatomic liquid -interacting through a two body potential that mimics that of lithium- across the liquid-glass transition. In the glassy phase we find evidences of a fast relaxation process similar to that recently found in Lennard-Jones glasses. The origin of this process is ascribed to the topological disorder, i.e. to the dephasing of the different momentum $Q$ Fourier components of the actual normal modes of vibration of the disordered structure. More important, we find that the fast relaxation persists in the liquid phase with almost no temperature dependence of its characteristic parameters (strength and relaxation time). We conclude, therefore, that in the liquid phase well above the melting point, at variance with the usual assumption of {\it un-correlated} binary collisions, the short time particles motion is strongly {\it correlated} and can be described via a normal mode expansion of the atomic dynamics.
description: 7 pages, 7 .eps figs. To appear in Phys. Rev. E
The Fall of a Giant. Chemical evolution of Enceladus, alias the Gaia Sausage
Creators: name: Vincenzo, Fiorenzo
name: Spitoni, Emanuele
name: Calura, Francesco
name: Matteucci, Francesca
name: Aguirre, Victor Silva
name: Miglio, Andrea
name: Cescutti, Gabriele
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the first chemical evolution model for Enceladus, alias the Gaia Sausage, to investigate the star formation history of one of the most massive satellites accreted by the Milky Way during a major merger event. Our best chemical evolution model for Enceladus nicely fits the observed stellar [$α$/Fe]-[Fe/H] chemical abundance trends, and reproduces the observed stellar metallicity distribution function, by assuming low star formation efficiency, fast infall time scale, and mild outflow intensity. We predict a median age for Enceladus stars $12.33^{+0.92}_{-1.36}$ Gyr, and - at the time of the merger with our Galaxy ($\approx10$ Gyr ago from Helmi et al.) - we predict for Enceladus a total stellar mass $M_{\star} \approx 5 \times 10^{9}\,\text{M}_{\odot}$. By looking at the predictions of our best model, we discuss that merger events between the Galaxy and systems like Enceladus may have inhibited the gas accretion onto the Galaxy disc at high redshifts, heating up the gas in the halo. This scenario could explain the extended period of quenching in the star formation activity of our Galaxy about 10 Gyr ago, which is predicted by Milky Way chemical evolution models, in order to reproduce the observed bimodality in [$α$/Fe]-[Fe/H] between thick- and thin-disc stars.
description: Accepted for publication in MNRAS Letters
Racial and ethnic disparities in the co‐occurrence of intellectual disability and autism: Impact of incorporating measures of adaptive functioning
Creators: name: Durkin, Maureen S.
name: Wiggins, Lisa D.
name: Rubenstein, Eric
name: Yeargin‐Allsopp, Marshalyn
name: Pazol, Karen
name: Furnier, Sarah M.
name: Nadler, Cy
name: Weismer, Susan Ellis
name: Rosenberg, Steven
name: Reyes, Nuri M.
name: Daniels, Julie L.
name: Gangnon, Ronald
Publisher: name: Wiley
Year: 2024

description: Intellectual disability (ID) commonly co-occurs in children with autism. Although diagnostic criteria for ID require impairments in both cognitive and adaptive functioning, most population-based estimates of the frequency of co-occurring ID in children with autism-including studies of racial and ethnic disparities in co-occurring autism and ID-base the definition of ID solely on cognitive scores. The goal of this analysis was to examine the effect of including both cognitive and adaptive behavior criteria on estimates of co-occurring ID in a well-characterized sample of 2- to 5-year-old children with autism. Participants included 3264 children with research or community diagnoses of autism enrolled in the population-based Study to Explore Early Development (SEED) phases 1-3. Based only on Mullen Scales of Early Learning (MSEL) composite cognitive scores, 62.9% (95% confidence interval [CI]: 61.1, 64.7%) of children with autism were estimated to have co-occurring ID. After incorporating Vineland Adaptive Behavior Scales, Second Edition (VABS-II) composite or domains criteria, co-occurring ID estimates were reduced to 38.0% (95% CI: 36.2, 39.8%) and 45.0% (95% CI: 43.1, 46.9%), respectively. The increased odds of meeting ID criteria observed for non-Hispanic (NH) Black and Hispanic children relative to NH White children when only MSEL criteria were used were substantially reduced, though not eliminated, after incorporating VABS-II criteria and adjusting for selected socioeconomic variables. This study provides evidence for the importance of considering adaptive behavior as well as socioeconomic disadvantage when describing racial and ethnic disparities in co-occurring ID in epidemiologic studies of autism.
A Conformal Mapping and Isothermal Perfect Fluid Model
Creators: name: Dadhich, Naresh
Publisher: name: arXiv
Year: 1996
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Instead of conformal to flat spacetime, we take the metric conformal to a spacetime which can be thought of as ``minimally'' curved in the sense that free particles experience no gravitational force yet it has non-zero curvature. The base spacetime can be written in the Kerr-Schild form in spherical polar coordinates. The conformal metric then admits the unique three parameter family of perfect fluid solution which is static and inhomogeneous. The density and pressure fall off in the curvature radial coordinates as $R^{-2}, $ for unbounded cosmological model with a barotropic equation of state. This is the characteristic of isothermal fluid. We thus have an ansatz for isothermal perfect fluid model. The solution can also represent bounded fluid spheres.
description: 10 pages, TeX version
Multiscale Modeling of Granular Materials
Creators: Liu, Yang
Publisher: name: Columbia University
Year: 2015
Subjects: subject: Mechanics
subject: Civil engineering
subject: FOS: Civil engineering
subject: Geotechnical engineering

description: Granular materials have a “discrete” nature whose global mechanical behaviors are originated from the grain scale micromechanical mechanisms. The intriguing properties and non-trivial behaviors of a granular material pose formidable challenges to the multiscale modeling of these materials. Some of the key challenges include upscaling of coarse-scale continuum equation form fine-scale governing equations, calibrating material parameters at different scales, alleviating pathological mesh dependency in continuum models, and generating unit cells with versatile morphological details. This dissertation aims to addressing the aforementioned challenges and to investigate the mechanical behavior of granular materials through multiscale modeling.
      Firstly, a three-dimensional nonlocal multiscale discrete-continuum model is presented for modeling the mechanical behavior of granular materials. We establish an information-passing coupling scheme between DEM that explicitly replicates granular motion of individual particles and a finite element continuum model, which captures nonlocal overall response of the granular assemblies. Secondly, a new staggered multilevel material identification procedure is developed for phenomenological critical state plasticity models. The emphasis is placed on cases in which available experimental data and constraints are insufficient for calibration. The key idea is to create a secondary virtual experimental database from high-fidelity models, such as discrete element simulations, then merge both the actual experimental data and secondary database as an extended digital database to determine material parameters for the phenomenological macroscopic critical state plasticity model. This expansion of database provides additional constraints necessary for calibration of the phenomenological critical state plasticity models.
      Thirdly, a regularized phenomenological multiscale model is investigated, in which elastic properties are computed using direct homogenization and subsequently evolved using a simple three-parameter orthotropic continuum damage model. The salient feature of the model is a unified regularization framework based on the concept of effective softening strain. The unified regularization scheme is employed in the context of constitutive law rescaling and the staggered nonlocal approach to alleviate pathological mesh dependency. Lastly, a robust parametric model is presented for generating unit cells with randomly distributed inclusions. The proposed model is computationally efficient using a hierarchy of algorithms with increasing computational complexity, and is able to generate unit cells with different inclusion shapes.