cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The medieval and later development of Reigate, excavations in Bell Street and High Street, 1979-1990
Creators: name: Williams, David W
name: Poulton, Rob
Publisher: name: Archaeology Data Service
Year: 2024

description: Spoilheap Monograph Series, 25
description: Excavations between 1988 and 1990, in advance of a planned retail redevelopment, focused on a large area to the south of High St and west of Bell St, the two streets that formed the core of historic Reigate. The work examined a range of frontage and backlands locations and, combined with a number of earlier investigations, provides an unusually comprehensive picture of the development of a small town.
The impact of a pharmacist-managed dosage form conversion service on ciprofloxacin usage at a major Canadian teaching hospital: a pre- and post-intervention study
Creators: name: Ho, Bradley P
name: Lau, Tim T
name: Balen, Robert M
name: Naumann, Terryn L
name: Jewesson, Peter J
Publisher: name: BioMed Central
Year: 2015

description: Background: Despite cost containment efforts, parenteral (IV) ciprofloxacin appears to be overutilized at Vancouver General Hospital. In November 2003, the Pharmacist-managed intravenous to oral (IV-PO) Dosage Form Conversion Service was implemented, enabling autonomous pharmacist-initiated dosage form conversion for ciprofloxacin. This study evaluates characteristics of ciprofloxacin use prior to and following implementation of this conversion service. Methods This was a single-centre, two-phase (pre/post), unblinded study. Phase I occurred between November 12, 2002 and November 11, 2003 (365 days), and Phase II between November 12, 2003 and March 11, 2004 (120 days). All patients receiving ciprofloxacin IV during these periods were reviewed. The primary endpoint was IV:PO ciprofloxacin use ratio. Secondary endpoints were total number of ciprofloxacin doses, proportion of inappropriate IV ciprofloxacin doses, cost of therapy between phases, and estimated cost avoidance with the intervention. Results Two hundred ciprofloxacin IV treatment courses were evaluated (100 per phase). The IV:PO ciprofloxacin use ratio was 3.03 (Phase I) vs. 3.48 (Phase II). Total number of doses and ratio of IV to total doses across phases were similar (p = 0.2830). IV-PO ciprofloxacin conversion occurred in 27/100 (27%) of IV courses in Phase I and 23/100 (23%) in Phase II. Proportion of inappropriate ciprofloxacin IV doses decreased between Phases I and II (244/521 (47%) vs. 201/554 (36%) (p = 0.0005), respectively). Furthermore, the proportion of pharmacist-preventable inappropriate ciprofloxacin IV doses was reduced between Phases I and II (114/244 (47%) vs. 65/201 (32%) (p = 0.0026). Proportional cost avoidance associated with total inappropriate IV use was $7,172/$16,517 (43%) (in Canadian dollars) in Phase I vs. $6,012/$17,919 (34%) in Phase II (p = 0.001). Similarly, proportional cost avoidance associated with pharmacist-preventable inappropriate IV doses was reduced from $3,367/$16,517 (20%) in Phase I to $1,975/$17,919 (11%) in Phase II (p = 0.001). Conclusion While overall utilization of ciprofloxacin remained unchanged and the proportion of IV to total doses was stable during the study period, the proportion of inappropriate IV doses and its associated costs appear to have declined subsequent to implementation of a Pharmacist-managed IV-PO Dosage Form Conversion Service. Such a program may be a beneficial adjunct in facilitating appropriate and cost-effective usage of ciprofloxacin.
The Norwich Survey: excavations in Norwich, 1971 - an interim report
Creators: name: Carter, Alan
Publisher: name: Archaeology Data Service
Year: 2020

description: Norfolk Archaeology, 35 (3), 410-416
description: TG 224088; 236092. Excavations in 1971 were designed to test a settlement model for the late 11th century extrapolated from 14th century documents. Three sites were dug, one in St Benedict's Street South and two in Bishopsgate. These produced structural and material evidence of all periods from late Saxon onwards which, taken with previous work in the city, agrees well with the postulated population distribution.
Excavations at North Elmham
Creators: name: Wade-Martins, Peter
Publisher: name: Archaeology Data Service
Year: 2020

description: Norfolk Archaeology, 35 (3), 416-427
description: [TF 9820]. The fifth season of work confirmed, with only minor changes, the sequence previously established. New finds include a bakehouse, followed in 8th century by a well and a cistern. During Phase II, AD 840-1000, there was a fifty-year gap in occupation followed by renewed activity. In Phase III at least six separate houses in their own enclosures included one 22ft x 47 with inset porch. Three boat-shaped houses in Phase IV, 1050-1175, may indicate a Scandinavian presence. More light has been thrown on development of building techniques. Monograph forthcoming.
Psittacosis infection and tracheobronchomalacia in a patient undergoing thyroidectomy
Creators: name: Diaz-Cano, Salvador J.
name: L Dixon
name: K M Sculte
Publisher: name: figshare
Year: 2012
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Medicine

description: A 34-year-old woman with papillary thyroid carcinoma underwent total thyroidectomy with central and lateral lymphadenectomy. Immediate airway compromise required re-intubation immediately after surgery. Marked tracheal and bronchial collapse of greater than 50% of the lumen indicated tracheobronchomalacia. Subsequent attempts at extubation failed over the next week. The patient soon developed evidence of a lower respiratory tract infection. Empirical treatment with penicillins was unsuccessful. A clinical suspicion of chlamydia infection prompted initiation of macrolide treatment followed by resolution of both the patient's respiratory infection and tracheobronchomalacia. Serology returned positive for Chlamydophila psittaci infection. It later transpired that the patient had symptoms of an upper respiratory tract infection just prior to surgery. This case demonstrates an interesting and unreported cause of tracheobronchomalacia as well as providing a good lesson on the importance of preoperative screening for infection.
Optimal Domain of generalized Volterra operators
Creators: name: Bellavita, Carlo
name: Daskalogiannis, Vasilis
name: Nikolaidis, Georgios
name: Stylogiannis, Georgios
Publisher: name: arXiv
Year: 2024
Subjects: subject: Complex Variables (math.CV)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 30H10, 47G10

description: For g in BMOA, we consider the generalized Volterra operator T_g acting on Hardy spaces H^p. This article aims to study the largest space of analytic functions, which is mapped by T_g into the Hardy space H^p. We call this space the optimal domain of T_g and we describe its structural properties. Motivation for this comes from the work of G. Curbera and W. Ricker who studied the optimal domain of the classical Cesáro operator.
description: No comments
Heterogeneous topographic profiles of kinetic and cell cycle regulator microsatellites in atypical (dysplastic) melanocytic nevi
Creators: name: Diaz-Cano, Salvador J.
name: Blanes, Alfredo
name: L Pozo-Garcia
name: E A Husain
name: C Mein
Publisher: name: figshare
Year: 2012
Subjects: Molecular Biology
Medicine
Cell Biology
Cancer

description: Atypical (dysplastic) melanocytic nevi are clinically heterogeneous malignant melanoma precursors, for which no topographic analysis of cell kinetic, cell cycle regulators and microsatellite profile is available. We selected low-grade atypical melanocytic nevi (92), high-grade atypical melanocytic nevi (41), melanocytic nevi (18 junctional, 25 compound) and malignant melanomas (16 radial growth phase and 27 vertical growth phase). TP53, CDKN2A, CDKN1A, and CDKN1B microsatellite patterns were topographically studied after microdissection; Ki-67, TP53, CDKN2A, CDKN1A, and CDKN1B expressions and DNA fragmentation by in situ end labeling for apoptosis were topographically scored. Results were statistically analyzed. A decreasing junctional-dermal marker expression gradient was observed, directly correlating with atypical melanocytic nevus grading. High-grade atypical melanocytic nevi revealed coexistent TP53-CDKN2A-CDKN1B microsatellite abnormalities, and significantly higher junctional Ki67-TP53 expression (inversely correlated with CDKN1A-CDKN1B expression and in situ end labeling). Malignant melanomas showed coexistent microsatellite abnormalities (CDKN2A-CDKN1B), no topographic gradient, and significantly decreased expression. Melanocytic nevi and low-grade atypical melanocytic nevi revealed sporadic junctional CDKN2A microsatellite abnormalities and no significant topographic kinetic differences. High-grade atypical melanocytic nevi accumulate junctional TP53-CDKN1A-CDKN1B microsatellite abnormalities, being progression TP53-independent and better assessed in the dermis. Melanocytic nevi and low-grade atypical melanocytic nevi show low incidence of microsatellite abnormalities, and kinetic features that make progression unlikely.
Thomas Heberer, Claudia Derichs (Hg.): Einführung in die politischen Systeme Ostasiens. VR China, Hongkong, Japan, Nordkorea, Südkorea, Taiwan
Creators: name: Runge, Wolfgang
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: ASIEN: The German Journal on Contemporary Asia, Nr. 109 (2008): ASIEN (Oktober)
Simple, efficient method of calculating the Detweiler-Whiting singular field to very high order
Creators: name: Bourg, Patrick
name: Pound, Adam
name: Upton, Samuel D.
name: Macedo, Rodrigo Panosso
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Most self-force calculations rely, in one way or another, on representations of a particle's Detweiler- Whiting singular field. We present a simple method of calculating the singular field to high order in a local expansion in powers of distance from the particle. As a demonstration, we compute the singular field to 14th order in distance, 10 orders beyond the previous state of the art, in the simple case of a scalar charge in circular orbit around a Schwarzschild black hole. We provide the result in both a 4-dimensional form and a decomposed form suitable for use in an m-mode puncture scheme. Our method should have applications in overcoming bottlenecks in current self-force calculations at both first and second order in perturbation theory.
description: 24 pages, 5 figures
Nonlinear Patterns of North American Winter Temperature and Precipitation Associated with ENSO.
Creators: name: Wu, Aiming
name: Hsieh, William W.
name: Shabbar, Amir
Publisher: name: American Meteorological Society
Year: 2016

description: Nonlinear projections of the tropical Pacific sea surface temperature anomalies (SSTAs) onto North American winter (November–March) surface air temperature (SAT) and precipitation anomalies have been performed using neural networks. During El Niño, the linear SAT response has positive anomalies centered over Alaska and western Canada opposing weaker negative anomalies centered over the southeastern United States. In contrast, the nonlinear SAT response, which is excited during both strong El Niño and strong La Niña, has negative anomalies centered over Alaska and northwestern Canada and positive anomalies over much of the United States and southern Canada. For precipitation, the linear response during El Niño has a positive anomaly area stretching from the east coast to the southwest coast of the United States and another positive area in northern Canada, in opposition to the negative anomaly area over much of southern Canada and northern United States, and another negative area over Alaska. In contrast, the nonlinear precipitation response, which is excited during both strong El Niño and strong La Niña, displays positive anomalies over much of the United States and southern Canada, with the main center on the west coast at around 45°N and a weak center along the southeast coast, and negative anomalies over northwestern Canada and Alaska. The nonlinear response accounts for about one-fourth and one-third as much variance as the linear response of the SAT and precipitation, respectively. A polynomial fit further verifies the nonlinear response of both the SAT and precipitation to be mainly a quadratic response to ENSO. Both the linear and nonlinear response patterns of the SAT and precipitation are basically consistent with the circulation anomalies (the 500-mb geopotential height anomalies), detected separately by nonlinear projection. A cross-validation test shows that including the nonlinear (quadratic) response can potentially contribute to additional forecast skill over North America. Copyright 2005 American Meteorological Society (AMS). Permission to use figures, tables, and brief excerpts from this work in scientific and educational works is hereby granted provided that the source is acknowledged. Any use of material in this work that is determined to be “fair use” under Section 107 of the U.S. Copyright Act or that satisfies the conditions specified in Section 108 of the U.S. Copyright Act (17 USC §108, as revised by P.L. 94-553) does not require the AMS’s permission. Republication, systematic reproduction, posting in electronic form, such as on a web site or in a searchable database, or other uses of this material, except as exempted by the above statement, requires written permission or a license from the AMS. Additional details are provided in the AMS Copyright Policy, available on the AMS Web site located at (http://www.ametsoc.org/) or from the AMS at 617-227-2425 or copyright@ametsoc.org.
Psychiatrische Kompetenzen für jedes Pflege-Setting : Stärkung des Fachbereichs Psychiatrie in einem Curriculum Bachelor Pflege
Creators: name: Fröbel, Rahel
name: Häusermann, Sara
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2024
Subjects: 378: Hochschulbildung
610.73: Pflege
616.89: Psychische Störungen, klinische Psychologie und Psychiatrie

description: Einleitung: Rund 30 % der Schweizer Bevölkerung zeigen Symptome von zumindest einer psychischen Erkrankung. Pflegefachpersonen benötigen entsprechend unabhängig von ihrem Arbeits-Setting Kompetenzen für die Pflege von psychisch erkrankten Personen. Bisher wurde psychiatrische Pflege in Studiengängen für Pflegefachpersonen meist im Rahmen eines einzelnen Moduls unterrichtet, bei dem der Fokus primär auf dem spezialisierten Psychiatrie-Setting lag.
Zielsetzung: Das Poster erläutert den innovativen curricularen Ansatz des Studiengangs Bachelor Pflege der Zürcher Hochschule für Angewandte Wissenschaften (ZHAW) in Bezug auf den Erwerb von Psychiatrie relevanten Pflegekompetenzen.
Methoden: Für den curricularen Themenstrang «Psychiatrie» wurden zwei Verantwortliche aus dem  Team bestimmt, welche über langjährige Erfahrung in der Psychiatriepflege verfügen, aktuell parallel zu ihrer Tätigkeit an der Fachhochschule in diesem Fachbereich arbeiten und die Modulverantwortung für das Psychiatrie-Modul innehaben. Zusammen mit Fachpersonen aus der Pflegepraxis und Modulverantwortlichen weiterer pflegespezifischer Module wurde das bestehende Curriculum über einen Zeitraum von zwei Jahren weiterentwickelt.
Ergebnisse: Es entstand ein sechssemestriges Curriculum Bachelor Pflege mit spiralförmigem Aufbau, in welchem die Studierenden - zusätzlich zum weiterhin bestehenden Psychiatrie-Modul – in jedem Semester Psychiatrie relevante Kompetenzen erwerben. Dabei wird auch ein Fokus auf die Betreuung von Personen mit psychiatrischen Herausforderungen in Pflege-Settings ausserhalb der akutstationären Psychiatrie gelegt. Es kommen verschiedene pädagogische Herangehensweisen wie Flipped Classroom oder Problem based Learning zum Einsatz. Bei zusätzlichem Besuch der themenspezifischen Wahlangebote können die Studierenden somit Psychiatrie relevante Kompetenzen im Umfang von bis zu 55 ECTS (1650 Lernstunden) erwerben. Modulevaluationen sowie der Austausch mit den in die Überarbeitung involvierten Personen und den Studierenden zeigen, dass alle Beteiligten einen deutlichen Mehrwert in der curricularen Weiterentwicklung verorten.
Diskussion: Insbesondere der spiralförmige Curriculum-Aufbau mit wiederkehrenden Themen von zunehmender Verarbeitungstiefe, aber auch die Integration von Psychiatrie relevanten Inhalten in diverse pflegespezifische Module, sensibilisieren die Bachelor Pflege-Studierenden bzgl. Wichtigkeit der Thematik und ermöglichen vertieftes Lernen.
Schlussfolgerung: Das Curriculum Bachelor Pflege der ZHAW hat durch diese Weiterentwicklung eine qualitative und quantitative Stärkung der Psychiatrie relevanten Inhalte erhalten, was den Studierenden einen vertiefteren Erwerb von fachrelevanten Kompetenzen auch ausserhalb des psychiatrischen Settings ermöglicht.
Scales of Stability and Turbulence in the Molecular ISM
Creators: name: Keto, Eric
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We re-analyze the data of the BU-FCRAO $^{13}{\rm CO}$ Galactic Ring Survey (GRS) to understand the dynamics of the turbulent molecular interstellar medium. We define molecular clouds by their spatial half-power contours of $^{13}{\rm CO}$ integrated intensity, independent of a boundary based on thresholding or tiling. We find properties of hydrostatic equilibrium (HE) and virial equilibrium (VE), the former independent and the latter dependent on time and spatial scales. We suggest that HE is a stationary property of the turbulence and that molecular clouds are high-density regions of a fluctuating component. The gravitational and turbulent kinetic energies within clouds are continuously evolving toward a time-dependent VE with the fluctuating, external, turbulent pressure energy (PE) that can be treated parametrically owing to the shorter time scale for virialization. The average PE is comparable to the pressure of the multiphase ISM at the Galactic mid-plane. Larson's scaling relations analyzed by different statistical methods are not significant. The non-dimensional variances of size, line width, and column density are of comparable magnitude, ruling out the inference of constant column density. Previously unrecognized autocorrelations may have contributed to the apparent validity of the inference.
description: Accepted by Astronomische Nachrichten
Archilestes latialatus Donnelly 1981
Creators: name: Garrison, R. W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Odonata
Lestidae
Archilestes
Archilestes latialatus

description: A. latialatus: Mexico: Veracruz, Laguna Emilia, 20 June 1971 (1 ♂) collected by R. Novelo; Guatemala: Alta Verapaz, Minas de Oxec, 10 km ESE of Cababon, 200 m, 12-14 June 1977 (1 ♂, paratype) collected by T. Donnelly; Costa Rica: Alajuela Prov., stream 7.3 mi SE San Ramon, 2900 ft., 19 June 1967 (1 ♂); Cartago Prov., stream at Pavones, 2800 ft., 2 Aug. 1966 (1 ♂)all collected by D.R. Paulson.
description: Published as part of Garrison, R. W., 1982, Archilestes neblina, a new damselfly from Costa Rica, with comments on the variability of A. latialatus Donnelly (Odonata: Lestidae), pp. 1-12 in Occasional Papers of the Museum of Zoology, University of Michigan 702 on page 11, DOI: 10.5281/zenodo.3535422
Asymmetries in invisible Dark Matter mediator production associated with $t \bar{t}$ final states
Creators: name: Chalbaud, E.
name: Silva, Rui M.
name: Onofre, António
name: Gonçalo, Ricardo
name: Fiolhais, Miguel C. N.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this paper, we propose two sets of different CP-sensitive observables inspired by the Higgs production in association with the top quark. We employ a Dark Matter simplified model that couples a scalar mediator with top quarks. The reconstruction of the kinematic variables is presented at NLO accuracy for events associated with this massive scalar particle, which is assumed to be vanishing to invisible decays in a detector such as ATLAS. We build these observables by taking advantage of the similarity between the scalar coupling with the top quark and the factorization theorem in the total scattering amplitude, in order to represent the basis in which the phase space is parameterized. A twofold approach employs the direct implementation of the four-momentum phase space measure in building CP sensitive observables such as $b_{2}$ for the Higgs, and the spin polarization of the top-quark decays in the narrow width approximation for the employed model. We studied the asymmetries of these distributions to test for any improvement in increasing the exclusion region for the $g_{u_{33}}^S-g_{u_{33}}^P$ parameters associated with this vanishing scalar particle. We have found no significant effect in the exclusion limits by using the forward-backward asymmetry distributions and the full-shaped ones. Considering the case of an invisible mediator with mass of 10$^{-2}$ GeV for a luminosity of 300 fb$^{-1}$ expected at the end of Run 3, the best limits for $g_{u_{33}}^S$ and $g_{u_{33}}^P$ at NLO accuracy were obtained using the variables ${\tilde{b}}_{2}^{\widehat{y}}$ and $b_{2}$ respectively, with corresponding limits set to $[-0.0425, 0.0425] $ and $[-0.83, 0.83]$ at $68\%$ CL.
description: 20 pages, 10 figures
Simple Parameterization Coupling the Convective Daytime Boundary Layer and Fair-Weather Cumuli.
Creators: name: Berg, Larry K.
name: Stull, Roland B., 1950-
Publisher: name: American Meteorological Society
Year: 2011

description: A new parameterization for boundary layer cumulus clouds, called the cumulus potential (CuP) scheme, is introduced. This scheme uses joint probability density functions (JPDFs) of virtual potential temperature ( ) and water-vapor mixing ratio (r), as well as the mean vertical profiles of , to predict the amount and size distribution of boundary layer cloud cover. This model considers the diversity of air parcels over a heterogeneous surface, and recognizes that some parcels rise above their lifting condensation level to become cumulus, while other parcels might rise as noncloud updrafts. This model has several unique features: 1) cloud cover is determined from the boundary layer JPDF of versus r, 2) clear and cloudy thermals are allowed to coexist at the same altitude, and 3) a range of cloud-base heights, cloud-top heights, and cloud thicknesses are predicted within any one cloud field, as observed. Using data from Boundary Layer Experiment 1996 and a model intercomparsion study using large eddy simulation (LES) based on Barbados Oceanographic and Meteorological Experiment (BOMEX), it is shown that the CuP model does a good job predicting cloud-base height and cloud-top height. The model also shows promise in predicting cloud cover, and is found to give better cloud-cover estimates than three other cumulus parameterizations: one based on relative humidity, a statistical scheme based on the saturation deficit, and a slab model. Copyright 2005 American Meteorological Society (AMS). Permission to use figures, tables, and brief excerpts from this work in scientific and educational works is hereby granted provided that the source is acknowledged. Any use of material in this work that is determined to be “fair use” under Section 107 of the U.S. Copyright Act or that satisfies the conditions specified in Section 108 of the U.S. Copyright Act (17 USC §108, as revised by P.L. 94-553) does not require the AMS’s permission. Republication, systematic reproduction, posting in electronic form, such as on a web site or in a searchable database, or other uses of this material, except as exempted by the above statement, requires written permission or a license from the AMS. Additional details are provided in the AMS Copyright Policy, available on the AMS Web site located at (http://www.ametsoc.org/) or from the AMS at 617-227-2425 or copyright@ametsoc.org.
Allele-specific binding variants causing ChIP-seq peak height of histone modification are not enriched in expression QTL annotations
Creators: name: GHOREISHIFAR, Seyed Mohammad
name: Chamberlain, Amanda
name: Xiang, Ruidong
name: Prowse-Wilkins, CP
name: Lopdell, TJ
name: Littlejohn, MD
name: Pryce, Jennie
name: Goddard, ME
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3105
subject: Genetics
classificationCode: 3102
subject: Bioinformatics and computational biology

description: Background: Genome sequence variants affecting complex traits (quantitative trait loci, QTL) are enriched in functional regions of the genome, such as those marked by certain histone modifications. These variants are believed to influence gene expression. However, due to the linkage disequilibrium among nearby variants, pinpointing the precise location of QTL is challenging. We aimed to identify allele-specific binding (ASB) QTL (asbQTL) that cause variation in the level of histone modification, as measured by the height of peaks assayed by ChIP-seq (chromatin immunoprecipitation sequencing). We identified DNA sequences that predict the difference between alleles in ChIP-seq peak height in H3K4me3 and H3K27ac histone modifications in the mammary glands of cows. Results: We used a gapped k-mer support vector machine, a novel best linear unbiased prediction model, and a multiple linear regression model that combines the other two approaches to predict variant impacts on peak height. For each method, a subset of 1000 sites with the highest magnitude of predicted ASB was considered as candidate asbQTL. The accuracy of this prediction was measured by the proportion where the predicted direction matched the observed direction. Prediction accuracy ranged between 0.59 and 0.74, suggesting that these 1000 sites are enriched for asbQTL. Using independent data, we investigated functional enrichment in the candidate asbQTL set and three control groups, including non-causal ASB sites, non-ASB variants under a peak, and SNPs (single nucleotide polymorphisms) not under a peak. For H3K4me3, a higher proportion of the candidate asbQTL were confirmed as ASB when compared to the non-causal ASB sites (P < 0.01). However, these candidate asbQTL did not enrich for the other annotations, including expression QTL (eQTL), allele-specific expression QTL (aseQTL) and sites conserved across mammals (P > 0.05). Conclusions: We identified putatively causal sites for asbQTL using the DNA sequence surrounding these sites. Our results suggest that many sites influencing histone modifications may not directly affect gene expression. However, it is important to acknowledge that distinguishing between putative causal ASB sites and other non-causal ASB sites in high linkage disequilibrium with the causal sites regarding their impact on gene expression may be challenging due to limitations in statistical power.
Testis-Preserving Surgery in the Management of Leydig Cell Tumours: The Importance of Pre- and Intra- Operative Ultrasound
Creators: name: Diaz-Cano, Salvador J.
name: G Muir
name: J Dockray
name: P Sidhu
Publisher: name: figshare
Year: 2012
Subjects: Medicine
Cancer

description: Introduction and Objectives
 Leydig cell tumours account for 1-3% of testicular neoplasms. Incidence occurs in two peaks, in the 5-10 (all benign) and 30-60 (90% benign) age range; 10% are bilateral. Presentation is usually as an incidental finding on a scrotal ultrasound, but hormone-secreting variants can present with symptoms of excessive androgenisation, feminisation or precocious puberty. Conventional management is radical inguinal orchidectomy, which can be seen as overtreatment in the vast majority.
 Materials and Methods
 We present, as an example, the case of a 31 year-old man with a contrast ultrasound diagnosed 3mm Leydig cell tumour and normal tumour markers. Management consisted of ultrasound-guided wide local excision through an inguinal approach. This approach allowed an estimated loss of only 5-10% testicular volume. Histology confirmed a benign Leydig cell tumour and all resection margins were clear. We currently have a series of eight partial orchidectomies for contrast ultrasound diagnosed Leydig cell tumours. There are characteristic ultrasound findings, enhanced by the use of contrast, that allow a higher confidence in the pre-operative diagnosis. This allows us to offer the option of partial orchidectomy without the need for intra-operative frozen section.
 Results
 From our eight patients, there are no incidences of local recurrences or distant metastatic disease. The follow-up period for these patients ranged from 8-48 months.
 Conclusions
 As a tumour that is predominantly benign and affects men for whom future fertility is a concern, the role of testis-conserving surgery is becoming an increasingly important consideration. Ultrasound is vital to make an accurate diagnosis and for intra-operative localisation of small, impalpable lesions. There is the option of utilising intra-operative frozen-section if the diagnosis is in doubt, although we do not find this to be necessary if contrast ultrasound imaging is used pre-operatively and an adequate cuff of tissue taken during resection. Careful selection of patients is key. We would recommend that this be considered for those with classic ultrasound images, small tumour mass and normal tumour markers.
Phase-space analysis of a two-section InP laser as an all-optical spiking neuron: dependency on control and design parameters
Creators: name: Puts, Lukas
name: Lenstra, Daan
name: Williams, Kevin
name: Yao, Weiming
Publisher: name: arXiv
Year: 2024
Subjects: subject: Optics (physics.optics)
subject: Signal Processing (eess.SP)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Using a rate-equation model we numerically evaluate the carrier concentration and photon number in an integrated two-section semiconductor laser, and analyse its dynamics in three-dimensional phase space. The simulation comprises compact model descriptions extracted from a commercially-available generic InP technology platform, allowing us to model an applied reverse-bias voltage to the saturable absorber. We use the model to study the influence of the injected gain current, reverse-bias voltage, and cavity mirror reflectivity on the excitable operation state, which is the operation mode desired for the laser to act as an all-optical integrated neuron. We show in phase-space that our model is capable of demonstrating four different operation modes, i.e. cw, self-pulsating and an on-set and excitable mode under optical pulse injection. In addition, we show that lowering the reflectivity of one of the cavity mirrors greatly enhances the control parameter space for excitable operation, enabling more relaxed operation parameter control and lower power consumption of an integrated two-section laser neuron.
description: 11 pages, 10 figures
Paratumoral gene expression profiles: promising markers of malignancy in melanocytic lesions
Creators: name: Diaz-Cano, Salvador J.
Publisher: name: figshare
Year: 2012
Subjects: Molecular Biology
Medicine
Cancer

description: Gene expression analysis is becoming a useful tool for a better definition of neoplasms at diagnostic, prognostic and predictive levels. A method for gene expression analysis from the corneal layer overlying melanocytic lesions (paratumoral gene expression) offers promising results. The identification of these markers and the negative predictive value (100%) make this test an excellent way for the screening and selection of atypical melanocytic lesions to be biopsied. However, the nature and biological meaning of these markers still need further studies and clarifications: origin of the tested RNA, mechanism of RNA transference, utility for subclassification of melanocytic lesions.
Archilestes regalis Gloyd 1944
Creators: name: Garrison, R. W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Odonata
Lestidae
Archilestes
Archilestes regalis

description: A. regalis: Mexico: San Luis Potosi, Rancho Quemado, route 85, km 353, near Tamazunchale, 5 Aug. 1966 (1 ♂) collected by O. S. Flint, Jr.
description: Published as part of Garrison, R. W., 1982, Archilestes neblina, a new damselfly from Costa Rica, with comments on the variability of A. latialatus Donnelly (Odonata: Lestidae), pp. 1-12 in Occasional Papers of the Museum of Zoology, University of Michigan 702 on page 11, DOI: 10.5281/zenodo.3535422
Augelite Raman and ATR-IR Fingerprints obtained with q-Gaussian and q-BWF deconvolutions made by means of Fityk Software
Creators: name: Sparavigna, Amelia Carolina
Publisher: name: Zenodo
Year: 2025
Subjects: Raman spectroscopy
ATR-IR spectroscopy
RRUFF Database
q-Gaussian functions
q-BWF functions
Augelite
aluminium phosphate minerals

description: This work is proposing the fingerprints of Raman and ATR-IR spectra of Augelite minerals. The Raman fingerprints are based on q-Gaussian functions deconvolution, whereas the ATR-IR fingerprints are obtained with q-Gaussian and q-BWF functions deconvolutions. q-Gaussian and q-BWF functions are implemented in Fityk software.
Eruptive lichen planus triggered by acupuncture
Creators: name: Diaz-Cano, Salvador J.
name: E Higgins
name: J Fleming
Publisher: name: figshare
Year: 2012
Subjects: Medicine

description: We report the case of a 41-year-old, previously fit and healthy woman who developed a widespread eruption following acupuncture treatment for musculoskeletal back pain. Four days after the treatment, she noticed a pruritic papular eruption on her lower back, where the acupuncture needles had punctured her skin. The eruption then spread to her feet, wrists, and chest. She took no regular medica- tions apart from levothyroxine for hypothyroidism and was penicillin allergic. On examination, we found that she had a florid, wide- spread eruption on her trunk and limbs, coalescing at skin fold sites on her back. On closer inspection, we noted dense crops of flat-topped, polygonal, red-brown and vio- laceous papules and plaques at sites of acupuncture needle placement on her lower back (Figure 1). The eruption also involved her trunk, back, and limbs, with dense foci on her wrists and ankles (Figure 2). Her face, palms, and soles were spared. She had a florid white lacy pat- tern consistent with Wickham striae on her buccal mu- cosa, but her genital mucosa was spared. The results of blood tests, including hepatitis B and C serologic assays, were unremarkable. A 4-mm punch biopsy specimen showed a dense bandlike lymphocytic infiltrate in the upper dermis obscuring the dermoepi- dermal junction, with some scattered lymphocytes and occasional eosinophils extending to the epidermis. The histologic findings therefore confirmed the diagnosis of widespread eruptive lichen planus.
Order evolution from a high-entropy matrix: understanding and predicting paths to low temperature equilibrium
Creators: name: Almishal, Saeed S. I.
name: Miao, Leixin
name: Tan, Yueze
name: Kotsonis, George N.
name: Sivak, Jacob T.
name: Alem, Nasim
name: Chen, Long-Qing
name: Crespi, Vincent H.
name: Dabo, Ismaila
name: Rost, Christina M.
name: Sinnott, Susan B.
name: Maria, Jon-Paul
Publisher: name: arXiv
Year: 2024
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Interest in high-entropy inorganic compounds originates from their ability to stabilize cations and anions in local environments that rarely occur at standard temperature and pressure. This leads to new crystalline phases in many-cation formulations with structures and properties that depart from conventional trends. The highest-entropy homogeneous and random solid-solution is a parent structure from which a continuum of lower-entropy offspring can originate by adopting chemical and/or structural order. This report demonstrates how synthesis conditions, thermal history, and elastic and chemical boundary conditions conspire to regulate this process in Mg0.2Co0.2Ni0.2Cu0.2Zn0.2O, during which coherent CuO nano-tweeds and spinel nano-cuboids evolve. We do so by combining structured synthesis routes, atomic-resolution microscopy and spectroscopy, density functional theory, and a phase field modeling framework that accurately predicts the emergent structure and local chemistry. This establishes a framework to appreciate, understand, and predict the macrostate spectrum available to a high-entropy system that is critical to rationalize property engineering opportunities.
Factors affecting learning organization development of supporting staffin Thonburi 1 Hospital
Creators: name: Phattarapon Nuwmtho
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University
Year: 2019
Subjects: learning organizational
supporting staff
Thonburi 1 Hospital

description: Journal of Management Science Nakhon Pathom Rajabhat University, 6, 2, 244-262
Система адресной продовольственной помощи: возможности и перспективы
Creators: name: Баскаков С.М.
Publisher: name: Региональная экономика: теория и практика
Year: 2013
Subjects: ПРОДОВОЛЬСТВЕННАЯ ПОМОЩЬ
СОЦИАЛЬНАЯ ПОДДЕРЖКА
РАСХОДЫ НА ПРОДОВОЛЬСТВИЕ
УРОВЕНЬ ДОХОДОВ
СЕЛЬСКОХОЗЯЙСТВЕННОЕ ПРОИЗВОДСТВО

description: В статье рассмотрены методологические основы реализации в РФ системы адресной (целевой) продовольственной помощи социально наименее защищенным слоям населения. Выделены критерии и принципы функционирования данной системы, определена ее форма. Разработана методика экономического обоснования эффективности системы и определения оптимального размера продовольственной помощи в стоимостном выражении, которая базируется на использовании уровня ежемесячных расходов населения на приобретение продуктов питания, величины ежемесячных среднедушевых денежных доходов, годового объема производства сельскохозяйственной продукции в регионе.
Charlotte Veit: Randnotitzen aus Kambodscha. Die Auslandsberichterstattung in der Bundesrepublik Deutschland über die Ereignisse nach dem Sturz des Pol-Pot-Regimes 1979
Creators: name: Görgen, Maraile
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: ASIEN: The German Journal on Contemporary Asia, Nr. 109 (2008): ASIEN (Oktober)
Risk or Chance? Large Language Models and Reproducibility in HCI Research
Creators: name: Kosch, Thomas
name: Feger, Sebastian
Publisher: name: arXiv
Year: 2024
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Reproducibility is a major concern across scientific fields. Human-Computer Interaction (HCI), in particular, is subject to diverse reproducibility challenges due to the wide range of research methodologies employed. In this article, we explore how the increasing adoption of Large Language Models (LLMs) across all user experience (UX) design and research activities impacts reproducibility in HCI. In particular, we review upcoming reproducibility challenges through the lenses of analogies from past to future (mis)practices like p-hacking and prompt-hacking, general bias, support in data analysis, documentation and education requirements, and possible pressure on the community. We discuss the risks and chances for each of these lenses with the expectation that a more comprehensive discussion will help shape best practices and contribute to valid and reproducible practices around using LLMs in HCI research.
description: Published in ACM Interactions
Проблемы обеспечения продовольственной безопасности региона
Creators: name: Терентьева О.Н.
name: Баскаков С.М.
Publisher: name: Национальные интересы: приоритеты и безопасность
Year: 2013
Subjects: ПРОДОВОЛЬСТВЕННАЯ БЕЗОПАСНОСТЬ
РЕГИОН
ЗАКОНОДАТЕЛЬСТВО
ЭФФЕКТИВНОСТЬ
ГОСУДАРСТВЕННАЯ ПОДДЕРЖКА

description: В статье оценены возможности применения Доктрины продовольственной безопасности Российской Федерации. Выделены факторы, не позволяющие в полной мере трансформировать проблему продовольственной безопасности на региональный уровень. Приведен сравнительный анализ отдельных показателей сельского хозяйства России с аналогичной практикой государств членов ЕС. Сделан вывод о необходимости формирования единого законодательства о продовольственной безопасности как на федеральном, так и на региональном уровне.
Archilestes tuberalatus
Creators: name: Garrison, R. W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Odonata
Lestidae
Archilestes
Archilestes tuberalatus

description: A. tuberalatus: Venezuela: Aragua State, Rancho Grande, 1000 m, 15 Dec. 1961 (1 ♂) collected by J. Racenis.
description: Published as part of Garrison, R. W., 1982, Archilestes neblina, a new damselfly from Costa Rica, with comments on the variability of A. latialatus Donnelly (Odonata: Lestidae), pp. 1-12 in Occasional Papers of the Museum of Zoology, University of Michigan 702 on page 11, DOI: 10.5281/zenodo.3535422
Phase-aggregated Dual-branch Network for Efficient Fingerprint Dense Registration
Creators: name: Guan, Xiongjun
name: Feng, Jianjiang
name: Zhou, Jie
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Fingerprint dense registration aims to finely align fingerprint pairs at the pixel level, thereby reducing intra-class differences caused by distortion. Unfortunately, traditional methods exhibited subpar performance when dealing with low-quality fingerprints while suffering from slow inference speed. Although deep learning based approaches shows significant improvement in these aspects, their registration accuracy is still unsatisfactory. In this paper, we propose a Phase-aggregated Dual-branch Registration Network (PDRNet) to aggregate the advantages of both types of methods. A dual-branch structure with multi-stage interactions is introduced between correlation information at high resolution and texture feature at low resolution, to perceive local fine differences while ensuring global stability. Extensive experiments are conducted on more comprehensive databases compared to previous works. Experimental results demonstrate that our method reaches the state-of-the-art registration performance in terms of accuracy and robustness, while maintaining considerable competitiveness in efficiency.
Eva Streifeneder, Antje Missbach (eds.): Indonesia - The Presence of the Past: A festschrift in honour of Ingrid Wessel
Creators: name: Findeisen, Genia
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: ASIEN: The German Journal on Contemporary Asia, Nr. 109 (2008): ASIEN (Oktober)
Seroprevalence of hepatitis A infection in a low endemicity country: a systematic review
Creators: name: Pham, Ba'
name: Duval, Bernard
name: De Serres, Gaston
name: Gilca, Vladimir
name: Tricco, Andrea C.
name: Ochnio, Jan
name: Scheifele, David W.
Publisher: name: BioMed Central
Year: 2015

description: Background: In Canada – a low endemicity country, vaccines for hepatitis A virus (HAV) are currently recommended to individuals at increased risk for infection or its complications. Applying these recommendations is difficult because the epidemiology of HAV infection is poorly defined, complex, and changing. This systematic review aimed to 1) estimate age-specific prevalence of HAV antibody in Canada and 2) evaluate infection-associated risk factors. Methods MEDLINE (1966–2005) and EMBASE (1980–2005) were searched to identify relevant studies for the systematic review. Archives for the Canada Diseases Weekly Report (1975–1991) and Canada Communicable Disease Report (1992–2005) were searched for relevant public health reports. Data were abstracted for study and participants' characteristics, age-specific prevalence, and risk factors. Results A total of 36 reports describing 34 unique studies were included. The seroprevalence in Canadian-born children was approximately 1% in ages 8–13, 1–6% in 20–24, 10% in 25–29, 17% in 30–39, and increased subsequently. In age groups below 20 and 20–29, age-specific seroprevalence generally remained constant for studies conducted across geographic areas and over time. Compared to Canadian-born individuals, subjects born outside Canada were approximately 6 times more likely to be seropositive (relative risk: 5.7 [95% CI 3.6, 9.0]). Travel to high risk areas in individuals aged 20–39 was associated with a significant increase in anti-HAV seropositivity (RR 2.8 [1.4, 5.5]). Compared to heterosexuals, men having sex with men were only at a marginally higher risk (adjusted odds ratio 2.4 [0.9, 6.1]). High risk for seropositivity was also observed for Canadian First Nations and Inuit populations. Conclusion Results from the current systematic review show that in this low endemicity country, disease acquisition occurs in adulthood rather than childhood. The burden of disease is high; approximately 1 in 10 Canadians had been infected by ages 24–29. The increase in prevalence in young adults coincides with disease importation and increasing frequency of risk factors, most likely behavioral-related ones. Gaps in seroprevalence data were identified rendering the application of current immunization recommendations difficult. A nationwide prevalence survey for all Canadians is needed. This is essential to quantify the effectiveness of current recommendations and conduct cost-effectiveness evaluations of alternative immunization programs, if necessary.
Contactifications: a Lagrangian description of compact Hamiltonian systems
Creators: name: Grabowska, Katarzyna
name: Grabowski, Janusz
name: Kuś, Marek
name: Marmo, Giuseppe
Publisher: name: arXiv
Year: 2024
Subjects: subject: Symplectic Geometry (math.SG)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 53D05, 53D10 (Primary) 53D35, 70Hxx, 70H25, 70S05 (Secondary)

description: If $η$ is a contact form on a manifold $M$ such that the orbits of the Reeb vector field form a simple foliation $\mathcal{F}$ on $M$, then the presymplectic 2-form $dη$ on $M$ induces a symplectic structure $ω$ on the quotient manifold $N=M/\mathcal{F}$. We call $(M,η)$ a $\textit contactification$ of the symplectic manifold $(N,ω)$. First, we present an explicit geometric construction of contactifications of some coadjoint orbits of connected Lie groups. Our construction is a far going generalization of the well-known contactification of the complex projective space $\mathbb{C}P^{n-1}$, being the unit sphere $S^{2n-1}$ in $\mathbb{C}^{n}$, and equipped with the restriction of the Liouville 1-form on $\mathbb{C}^n$. Second, we describe a constructive procedure for obtaining contactification in the process of the Marsden-Weinstein-Meyer symplectic reduction and indicate geometric obstructions for the existence of compact contactifications. Third, we show that contactifications provide a nice geometrical tool for a Lagrangian description of Hamiltonian systems on compact symplectic manifolds $(N,ω)$, on which symplectic forms never admit a `vector potential'.
description: 30 pages
Karel Steenbrink: Catholics in Indonesia, 1808-1942. A documented History, Volume 2. The spectacular growth of a self confident minority 1903-1942
Creators: name: Müller, Johannes
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: ASIEN: The German Journal on Contemporary Asia, Nr. 109 (2008): ASIEN (Oktober)