cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Two-qudit topological phase evolution under dephasing
Creators: name: Oxman, L. E.
name: Khoury, A. Z.
name: Lombardo, F. C.
name: Villar, P. I.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this work, we study a bipartite system composed by a pair of entangled qudits coupled to an environment. Initially, we derive a master equation and show how the dynamics can be restricted to a "diagonal" sector that includes a maximally entangled state (MES). Next, we solve this equation for mixed qutrit pairs and analyze the $I$-concurrence $C(t)$ for the effective state, which is needed to compute the geometric phase when the initial state is pure. Unlike (locally operated) isolated systems, the coupled system leads to a nontrivial time-dependence, with $C(t)$ generally decaying to zero at asymptotic times. However, when the initial condition gets closer to a MES state, the effective concurrence is more protected against the effects of decoherence, signaling a transition to an effective two-qubit MES state at asymptotic times. This transition is also observed in the geometric phase evolution, computed in the kinematic approach. Finally, we explore the system-environment coupling parameter space and show the existence of a Weyl symmetry among the various physical quantities.
description: 31 pages, 26 figures
Probing the Structure and in Silico Stability of Cargo Loaded DNA Icosahedron using MD Simulations
Creators: name: Joshi, Himanshu
name: Bhatia, Dhiraj
name: Krishnan, Yamuna
name: Maiti, Prabal K.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Biological Physics (physics.bio-ph)
subject: Chemical Physics (physics.chem-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Platonic solids such as polyhedra based on DNA have been deployed for multifarious applications such as RNAi delivery, biological targeting and bioimaging. All of these applications hinge on the capability of DNA polyhedra for molecular display with high spatial precision. Therefore high resolution structural models of such polyhedra are critical to widen their applications in both materials and biology. Here, we present an atomistic model of a well-characterized DNA icosahedron, with demonstrated versatile functionalities in biological systems. We study the structure and dynamics of this DNA icosahedron using fully atomistic molecular dynamics simulation in explicit water and ions. The major modes of internal motion have been identified using principal component analysis. We provide a quantitative estimate of the radius of gyration (Rg), solvent accessible surface area (SASA) and volume of the icosahedron which is essential to estimate its maximal cargo carrying capacity. Importantly, our simulation of gold nanoparticles (AuNP) encapsulated within DNA icosahedra revealed enhanced stability of the AuNP loaded DNA icosahedra compared to empty icosahedra. This is consistent with experimental results that show high yields of cargo-encapsulated DNA icosahedra that have led to its diverse applications for precision targeting. These studies reveal that the stabilizing interactions between the cargo and the DNA scaffold powerfully positions DNA polyhedra as targetable nanocapsules for payload delivery. These insights can be exploited for precise molecular display for diverse biological applications.
description: 46 pages, 16 Figures and 3 Tables, Accepted for publication in Nanoscale
Additional file 1: of Global terrain classification using 280Â m DEMs: segmentation, clustering, and reclassification
Creators: name: Iwahashi, Junko
name: Kamiya, Izumi
name: Matsuoka, Masashi
name: Yamazaki, Dai
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: Cross tabulation results and graphs with the reference numbers of clusters in Japan. (PDF 530Â kb)
Transition from turbulent to coherent flows in confined three-dimensional active fluids
Creators: name: Wu, Kun-Ta
name: Hishamunda, Jean Bernard
name: Chen, Daniel T. N.
name: DeCamp, Stephen J.
name: Chang, Ya-Wen
name: Fernández-Nieves, Alberto
name: Fraden, Seth
name: Dogic, Zvonimir
Publisher: name: arXiv
Year: 2017
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: Transport of fluid through a pipe is essential for the operation of macroscale machines and microfluidic devices. Conventional fluids only flow in response to external pressure. We demonstrate that an active isotropic fluid, comprised of microtubules and molecular motors, autonomously flows through meter-long three-dimensional channels. We establish control over the magnitude, velocity profile and direction of the self-organized flows, and correlate these to the structure of the extensile microtubule bundles. The inherently three-dimensional transition from bulk-turbulent to confined-coherent flows occurs concomitantly with a transition in the bundle orientational order near the surface, and is controlled by a scale-invariant criterion related to the channel profile. The non-equilibrium transition of confined isotropic active fluids can be used to engineer self-organized soft machines.
Studying the ISM in high-redshift strongly gravitational lensed galaxies in the ALMA era
Creators: name: Yang, Chentao
Publisher: name: Zenodo
Year: 2020

description: The discovery of a population of high-redshift dust-obscured submillimeter galaxies (SMGs) has revolutionized our understanding of galaxy evolution and star formation in extreme conditions, yet their nature remains hotly debated. Recent wide-area extragalactic surveys at submm/mm bands have discovered hundreds of strongly gravitational lensed SMGs. The boosted angular resolution and brightness of the lensed SMGs opens new exciting opportunities for observing the interstellar medium in these exceptional objects. We have thus carefully selected a sample of the brightest strongly lensed SMGs based on the Herschel-ATLAS sample. Using IRAM telescopes, we observed multiple transitions of the CO lines and analysis the physical conditions of the molecular gas. The first multiple transitions of the submm H2O line survey at high-redshift was also conducted within our sample. Through these lines, we have studied the properties of the far-IR radiation fields that they trace primarily, which provide us new constraints of the warm dense, extreme dust-obscured regions. ALMA 0".2-0".4 follow-up of one of the brightest sources (G09v1.97) in our sample shows very well agreement of the spatial distribution and kinematics between the CO(6-5), H2O(211-202) and H2O+(202-111) lines. Interestingly, this merger shows a mismatch between the cold-dust continuum peak and the peak of the line emissions, suggesting a significant amount of cold gas is in the interacting region, similar to the local merger prototype, the Antennae galaxies. In parallel, we have conducted a line survey in Band 3 and 4 using ALMA, which resulted in detections of a rich family of molecules including HCN, HCO+, CCH, 13CO, C18O, C17O, C18O, CS, NH2, and including the first detection of the 448GHz H2O emission at high-redshift. The rich detections of molecules in multiple transitions enable us for the first time to have a detailed view of the astrochemical process and reveal rich information about the physical properties of the molecular gas, the radiation field, and their interactions at high-redshift.
Veronica verna var. revelieri Briq.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Plantaginaceae
Veronica
Veronica verna
Veronica verna var. revelieri briq.

description: Veronica verna var. revelieri Briq. in Annuaire Conserv. Jard. Bot. Genève 9: 173. 1905.
Holotypus: FRANCE. Corse: Monte d’Oro, versant E, 1800-1900 m, 11.VI.1904, E. Burnat, J. Burnat, Cavillier & Abrezol 516 (G-BU [G00830087]!).
= Veronica verna subsp. brevistyla (Moris) Rouy
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 73, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
Ferromagnetism in chiral multilayer 2D semimetals
Creators: name: Min, Hongki
name: Hwang, E. H.
name: Sarma, S. Das
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We calculate the temperature dependent long-range magnetic coupling in the presence of dilute concentrations of random magnetic impurities in chiral multilayer two-dimensional semimetals, i.e., undoped intrinsic multilayer graphene. Assuming a carrier-mediated indirect RKKY exchange interaction among the well-separated magnetic impurities with the itinerant carriers mediating the magnetic interaction between the impurities, we investigate the magnetic properties of intrinsic multilayer graphene using an effective chiral Hamiltonian model. We find that due to the enhanced density of states in the rhombohedral stacking sequence of graphene layers, the magnetic ordering of multilayer graphene is ferromagnetic in the continuum limit. The ferromagnetic transition temperature is calculated using a finite-temperature self-consistent field approximation and found to be within the experimentally accessible range for reasonable values of the impurity-carrier coupling.
description: 8 pages, 5 figures
Superfluidity and relaxation dynamics of a laser-stirred 2D Bose gas
Creators: name: Singh, Vijay Pal
name: Weitenberg, Christof
name: Dalibard, Jean
name: Mathey, Ludwig
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the superfluid behavior of a two-dimensional (2D) Bose gas of $^{87}$Rb atoms using classical field dynamics. In the experiment by R. Desbuquois \textit{et al.}, Nat. Phys. \textbf{8}, 645 (2012), a 2D quasicondensate in a trap is stirred by a blue-detuned laser beam along a circular path around the trap center. Here, we study this experiment from a theoretical perspective. The heating induced by stirring increases rapidly above a velocity $v_c$, which we define as the critical velocity. We identify the superfluid, the crossover, and the thermal regime by a finite, a sharply decreasing, and a vanishing critical velocity, respectively. We demonstrate that the onset of heating occurs due to the creation of vortex-antivortex pairs. A direct comparison of our numerical results to the experimental ones shows good agreement, if a systematic shift of the critical phase-space density is included. We relate this shift to the absence of thermal equilibrium between the condensate and the thermal wings, which were used in the experiment to extract the temperature. We expand on this observation by studying the full relaxation dynamics between the condensate and the thermal cloud.
description: 11 pages, 9 figures, 1 table
Bifurcations of the conjugate locus
Creators: name: Waters, Thomas
Publisher: name: arXiv
Year: 2017
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: The conjugate locus of a point $p$ in a surface $\mathcal{S}$ will have a certain number of cusps. As the point $p$ is moved in the surface the conjugate locus may spontaneously gain or lose cusps. In this paper we explain this `bifurcation' in terms of the vanishing of higher derivatives of the exponential map; we derive simple equations for these higher derivatives in terms of scalar invariants; we classify the bifurcations of cusps in terms of the local structure of the conjugate locus; and we describe an intuitive picture of the bifurcation as the intersection between certain contours in the tangent plane.
description: Accepted in Journal of Geometry and Physics April 2017
Vicia sativa var. spodioides Briq.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Vicia
Vicia sativa
Vicia sativa var. spodioides briq.

description: Vicia sativa var. spodioides Briq., Prodr. Fl. Corse 2/1: 382. 1913.
Holotypus: FRANCE. Corse: Aleria, 30 - 40 m, 1.V.1907, Briquet, Saint-Yves & Cavillier 1393 (G-BU [G00830046]!).
= Vicia sativa L. subsp. sativa
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 73, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
Radiotherapy with or without immunotherapy in metastatic melanoma: efficacy and tolerability
Creators: name: Backlund, Ellen
name: Grozman, Vitali
name: Brage, Suzanne Egyhazi
name: Lewensohn, Rolf
name: Lindberg, Karin
name: Helgadottir, Hildur
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Mental Health
subject: Plant Biology
subject: FOS: Biological sciences

description: Radiotherapy (RT) is primarily considered as a palliative treatment in patients with metastatic melanoma. However, observations suggest that when RT is combined with immune checkpoint inhibitors (ICI), it can induce an immune response leading to an anti-tumoral effect also distant from the irradiated area – a phenomenon called ‘abscopal effect’. The frequency and circumstances of abscopal effect among metastatic melanoma patients remains uncertain and further research is necessary. This retrospective study included all metastatic melanoma patients who received non-stereotactic RT in Stockholm, Sweden in 2015–2020. Patients were grouped depending on if RT was given at start of ICI (RT + ICI(start)), at ICI progression (RT + ICI(salvage)) or without ICI (RT(only)). Response rates in irradiated (RR(irradiated)) and overall response rates in non-irradiated (ORR(non-irradiated)) metastases were evaluated together with survival and toxicity in each cohort. In the RT + ICI(start) (n = 47), RT + ICI(salvage) (n = 41) and RT(only) (n = 55) cohorts, RR(irradiated) was 70.7%, 67.5% and 43.1% (p = 0.018) while the ORR(non-irradiated) was 36.1%, 14.8% and 0.0% (p = 0.003), and the median overall survival was 18.2, 15.0 and 7.2 months, respectively (p = 0.014). Local response to RT was in all cohorts associated with longer survival (p < 0.001). The frequency of grade ≥3 immune-related adverse events was 17.0% and 19.5% in the RT + ICI(start) and RT + ICI(salvage) cohorts. No increased frequency of RT-related adverse events was seen in the RT + ICI cohorts, compared to the RT(only) cohort. This retrospective study showed that melanoma patients receiving RT in combination with ICI had a superior antitumoral response in both irradiated and non-irradiated lesions as compared to patients receiving only RT. Additionally, a subgroup of patients receiving RT when progressing on ICI experienced tumor regression also in non-irradiated areas.
Additional file 2: of Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana
Creators: name: Amoah, Linda
name: Acquah, Festus
name: Ayanful-Torgby, Ruth
name: Akua Oppong
name: Abankwa, Joana
name: Evans Obboh
name: Susheel Singh
name: Theisen, Michael
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Figure S1. Representative agarose gel images of msp2 amplified products. Identification of the FC27 msp2 allelic family members using the S1fw and M5 primer set (a) and the 3D7 msp2 allelic family members using S1fw and N5 primer set (b). Lane N: no template (water) negative control; Lane C1: 3D7 positive control sample; Lanes C2: FC27 positive control sample: Lanes 1â 14: samples collected in April from children living in Obom. The samples were scored as clonal or multiclonal for msp2 depending on the number of PCR products per sample. (DOCX 499 kb)
Thermal stiffening of clamped elastic ribbons
Creators: name: Wan, Duanduan
name: Nelson, David R.
name: Bowick, Mark J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We use molecular dynamics to study the vibrations of a thermally fluctuating two-dimensional elastic membrane clamped at both ends. We directly extract the eigenmodes from resonant peaks in the frequency domain of the time-dependent height and measure the dependence of the corresponding eigenfrequencies on the microscopic bending rigidity of the membrane, taking care also of the subtle role of thermal contraction in generating a tension when the projected area is fixed. At finite temperatures we show that the effective (macroscopic) bending rigidity tends to a constant as the bare bending rigidity vanishes, consistent with theoretical arguments that the large-scale bending rigidity of the membrane arises from a strong thermal renormalization of the microscopic bending rigidity. Experimental realizations include covalently-bonded two-dimensional atomically thin membranes such as graphene and molybdenum disulfide or soft matter systems such as the spectrin skeleton of red blood cells or diblock copolymers.
description: 7 pages, 5 figures
Additional file 1 of Treatment of mantle cell lymphoma in Asia: a consensus paper from the Asian Lymphoma Study Group
Creators: name: Yoon, Dok Hyun
name: Cao, Junning
name: Chen, Tsai-Yun
name: Izutsu, Koji
name: Kim, Seok Jin
name: Kwong, Yok Lam
name: Lin, Tong Yu
name: Thye, Lim Soon
name: Xu, Bing
name: Yang, Deok Hwan
name: Kim, Won Seog
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology
subject: Computational Biology

description: Additional file 1: Supplementary Appendix. Specifically used regimens in Asia
Treatment patterns, survival, and healthcare utilisation and costs in patients with locally advanced and metastatic bladder cancer in Denmark 2015–2020
Creators: name: Nørgaard, Mette
name: Mailhac, Aurélie
name: Fagerlund, Karin
name: Strunz-McKendry, Torsten
name: Agerbæk, Mads
name: Jensen, Jørgen Bjerggaard
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Computational Biology

description: Treatment patterns in locally advanced and metastatic urothelial bladder cancer (La/mUBC) is changing, but little is known about current treatment patterns, survival, and costs of these patients. Our aim was to describe treatment patterns, survival, and healthcare utilisation/costs in Danish La/mUBC patients in a routine clinical care setting. Registry-based nationwide cohort study including all bladder cancer patients aged 18 years or older with a La/mUBC tumour in the pathology register and a concomitant bladder cancer diagnosis in the Danish National Patient Registry in the period 2015–2020. We categorised the patients according to (1) La/mUBC at time of first bladder cancer diagnosis (de novo La/mUBC) and (2) non-invasive or localised muscle-invasive bladder cancer at time of diagnosis which had progressed to La/mUBC. All patients were included at date of pathology-confirmed La/mUBC. Follow-up ended 30 September 2022. We identified 1278 patients (69% men) with La/mUBC and no other previous cancer. Of these, 212 (17%) had de novo La/mUBC, while 1066 (83%) had progressed to La/mUBC. Median age was 72 years. Patients were followed for a median of 13.0 months (interquartile range 4.7;32.0). During follow-up, 651 (51%) patients started first-line treatment, of these, 285 progressed to second-line treatment, and 112 also started third-line treatment. Median survival was 13.0 months from La/mUBC diagnosis, 12.1 months from start of first-line treatment, 9.8 months from start of second-line treatment, and 8.6 months from start of third-line treatment. The mean number of days admitted to hospital was 3.47, 3.97, and 4.07 per month following initiation of first-line, second-line, and third-line treatment, respectively. Patients with La/mUBC have a poor prognosis, and in routine clinical care only around half of the patients received systemic anti-cancer treatment suggesting an unmet need for novel treatments. The overall costs only increased slightly from first to third-line treatment.
Vincetoxicum officinale var. burnatii Briq.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Gentianales
Apocynaceae
Vincetoxicum
Vincetoxicum officinale
Vincetoxicum officinale var. burnatii briq.

description: Vincetoxicum officinale var. burnatii Briq. in Annuaire Conserv. Jard. Bot. Genève 5: 110. 1901.
Holotypus: FRANCE. Corse: Monte Cinto, versant S, 1700-2000 m, 17.VII.1900, E. Burnat, Briquet & Cavillier 109 (G-BU [G00830031]!).
= Vincetoxicum hirundinaria subsp. contiguum (W.D.J. Koch) Markgr.
Holotypus: FRANCE. Corse: de Zicavo à l’Incudine, bergeries d’Aluccia, 1500 m, 18.VII.1906, E. Burnat, Briquet, Saint-Yves, Cavillier & Abrezol 1155 (G-BU [G00830045]!).
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 73, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
Tyrimnus leucographus var. cavillieri Briq.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Tyrimnus
Tyrimnus leucographus
Tyrimnus leucographus var. cavillieri briq.

description: Tyrimnus leucographus var. cavillieri Briq. in Annuaire Conserv. Jard. Bot. Genève 9: 181. 1905.
Holotypus: FRANCE. Corse: entre Sagone et Cargèse, près des rives de la mer, 26.V.1904, E. Burnat, J. Burnat, Cavillier & Abrezol 517 (G-BU [G00830021]!).
= Tyrimnus leucographus (L.) Cass.
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 73, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
Combined atomic force microscopy and photoluminescence imaging to select single InAs/GaAs quantum dots for quantum photonic devices
Creators: name: Sapienza, Luca
name: Liu, Jin
name: Song, Jin Dong
name: Falt, Stefan
name: Wegscheider, Werner
name: Badolato, Antonio
name: Srinivasan, Kartik
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We report on a combined photoluminescence imaging and atomic force microscopy study of single, isolated self-assembled InAs quantum dots (density <0.01 um^(-2) capped by a 95 nm GaAs layer, and emitting around 950 nm. By combining optical and scanning probe characterization techniques, we determine the position of single quantum dots with respect to comparatively large (100 nm to 1000 nm in-plane dimension) topographic features. We find that quantum dots often appear (>25% of the time) in the vicinity of these features, but generally do not exhibit significant differences in their non-resonantly pumped emission spectra in comparison to quantum dots appearing in defect-free regions. This behavior is observed across multiple wafers produced in different growth chambers. Our characterization approach is relevant to applications in which single quantum dots are embedded within nanofabricated photonic devices, where such large surface features can affect the interaction with confined optical fields and the quality of the single-photon emission. In particular, we anticipate using this approach to screen quantum dots not only based on their optical properties, but also their surrounding surface topographies.
description: 7 pages, 4 figures
Real-world analysis of MET exon 14 mutations in non-small cell lung cancer: a retrospective study from two Swedish hospitals
Creators: name: Skribek, Marcus
name: Brunnström, Hans
name: Oskarsdottir, Gudrun
name: Grivé, Mikel Portu
name: Aricak, Ozan
name: Planck, Maria
name: Jatta, Kenbugul
name: Naserhojati, Homeyra
name: de Flon, Felix Haglund
name: Ekman, Simon
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Real-World evidence on mesenchymal-epithelial transition exon 14 skipping mutations (METex14) in lung cancer remains limited. With an incidence of 3–4% across histological subtypes, METex14 is now an actionable target for MET inhibitors (METi) in advanced lung cancer, demonstrating response rates between 30–70%. Yet, its role in early stages and sensitivity to immune checkpoint inhibitors (ICIs) is still under exploration. We conducted a retrospective analysis of the clinical data of lung cancer patients presenting with METex14 across all stages. These patients were treated at two Swedish University Hospitals: Karolinska and Skåne, between the years 2014 and 2022. We identified a total of 63 patients, of which 50 met the inclusion criteria. The median overall survival (OS) with corresponding 95% confidence intervals (95% CI) according to the stage was not reached (NR) for stage I, NR for stage II, 15 months (95% CI, 5.4–24.6) for stage III, and 17 months (95% CI, 9.2–NR) for stage IV. The median OS for stage IV patients who received a METi was 17 months (95% CI, 9.5–NR) vs. 10 months (95% CI, 6.2–NR) in patients without METi (p = 0.92; Hazard Ratio [HR] = 1.07). The median OS for stage IV patients who received ICIs was 18 months (95% CI, 16.5–NR) vs. 6 months (95% CI, 2.5–NR) in patients without ICIs (p = 0.15; HR = 0.47). The median OS for stage IV patients who received chemotherapy was 17 months (95% CI, 9.7–NR) vs. 10 months (95% CI, 4.5–NR) in patients without (p = 0.97; HR = 0.98). Our data suggest limited survival benefits from METi, ICIs, and chemotherapy for METex14 lung cancer patients. While not statistically significant, these findings underscore the need for larger trials for validation. Identifying effective treatments for this challenging lung cancer subtype remains a priority.
HISMACITY pro research reports and Model Builder
Creators: name: Pica, Valentina
Publisher: name: Zenodo
Year: 2020

description: HISMACITY pro research reports and GIS model builder document, describing the formula of the composite indicators. The compressed folder contains the description of the first analysis and construction of the structure and the contents of the Protocol in the first report, of the research material and other important documents used in the research and production of the HISMACITY protocol for integrated interventions for the requalification of small historic centers.
Fermi LAT observation of VER J2019+407
Creators: name: Araya, Miguel
name: Fraija, Nissim
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Analysis of data from the Fermi Large Area Telescope (LAT) in the region of the supernova remnant G78.2+2.1 reveals an excess at the position of the TeV source VER J2019+407. The GeV source is extended with a hard spectrum and it is likely the counterpart of the TeV source. The spectrum of the LAT emission connects smoothly with that of VER J2019+407, and the overall GeV--TeV spectrum is best described by a broken power-law with indices 1.8 and 2.5 below and above a break energy of 71 GeV. Several scenarios are considered to explain the nature of this unidentified gamma ray source.
description: Published in the proceedings of the conference 6th International Meeting on High-Energy Gamma-Ray Astronomy (Gamma2016), Heidelberg, Germany
Radiotherapy with or without immunotherapy in metastatic melanoma: efficacy and Tolerability
Creators: name: Backlund, Ellen
name: Grozman, Vitali
name: Brage, Suzanne Egyhazi
name: Lewensohn, Rolf
name: Lindberg, Karin
name: Helgadottir, Hildur
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Mental Health
subject: Plant Biology
subject: FOS: Biological sciences

description: Radiotherapy (RT) is primarily considered as a palliative treatment in patients with metastatic melanoma. However, observations suggest that when RT is combined with immune checkpoint inhibitors (ICI), it can induce an immune response leading to an anti-tumoral effect also distant from the irradiated area – a phenomenon called ‘abscopal effect’. The frequency and circumstances of abscopal effect among metastatic melanoma patients remains uncertain and further research is necessary. This retrospective study included all metastatic melanoma patients who received non-stereotactic RT in Stockholm, Sweden in 2015–2020. Patients were grouped depending on if RT was given at start of ICI (RT + ICI(start)), at ICI progression (RT + ICI(salvage)) or without ICI (RT(only)). Response rates in irradiated (RR(irradiated)) and overall response rates in non-irradiated (ORR(non-irradiated)) metastases were evaluated together with survival and toxicity in each cohort. In the RT + ICI(start) (n = 47), RT + ICI(salvage) (n = 41) and RT(only) (n = 55) cohorts, RR(irradiated) was 70.7%, 67.5% and 43.1% (p = 0.018) while the ORR(non-irradiated) was 36.1%, 14.8% and 0.0% (p = 0.003), and the median overall survival was 18.2, 15.0 and 7.2 months, respectively (p = 0.014). Local response to RT was in all cohorts associated with longer survival (p < 0.001). The frequency of grade ≥3 immune-related adverse events was 17.0% and 19.5% in the RT + ICI(start) and RT + ICI(salvage) cohorts. No increased frequency of RT-related adverse events was seen in the RT + ICI cohorts, compared to the RT(only) cohort. This retrospective study showed that melanoma patients receiving RT in combination with ICI had a superior antitumoral response in both irradiated and non-irradiated lesions as compared to patients receiving only RT. Additionally, a subgroup of patients receiving RT when progressing on ICI experienced tumor regression also in non-irradiated areas.
Additional file 5 of Tumor necrosis factor α in aGVHD patients contributed to the impairment of recipient bone marrow MSC stemness and deficiency of their hematopoiesis-promotion capacity
Creators: name: Ding, Li
name: Ning, Hong-Mei
name: Li, Pei-Lin
name: Yan, Hong-Min
name: Han, Dong-Mei
name: Zheng, Xiao-Li
name: Liu, Jing
name: Zhu, Ling
name: Xue, Mei
name: Mao, Ning
name: Guo, Zi-Kuan
name: Zhu, Heng
name: Wang, Heng-Xiang
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 5: Table S1. Patient Characteristics.
Additional file 1: of Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana
Creators: name: Amoah, Linda
name: Acquah, Festus
name: Ayanful-Torgby, Ruth
name: Akua Oppong
name: Abankwa, Joana
name: Evans Obboh
name: Susheel Singh
name: Theisen, Michael
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Table S1. msp2 and GLURP genotyping primers. Details of the primers used for the msp2 and GLURP genotyping reactions, including the primer name, sequence and annealing temperatures are listed in the table. (DOCX 15 kb)
The second bosonization of the CKP hierarchy
Creators: name: Anguelova, Iana I.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mathematical Physics (math-ph)
subject: Quantum Algebra (math.QA)
subject: Representation Theory (math.RT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: In this paper we discuss the second bosonization of the Hirota bilinear equation for the CKP hierarchy introduced by Date, Jimbo, Kashiwara and Miwa. We show that there is a second, untwisted, Heisenberg action on the Fock space, in addition to the twisted Heisenberg action suggested by Date, Jimbo, Kashiwara and Miwa and studied by van de Leur, Orlov and Shiota. We derive the decomposition of the Fock space into irreducible Heisenberg modules under this action. We show that the space spanned by the highest weight vectors of the irreducible Heisenberg modules has a structure of a super vertex algebra, specifically the symplectic fermions vertex algebra. We complete the second bosonization of the CKP Hirota equation by expressing the generating field via exponentiated boson vertex operators acting on a polynomial algebra with two infinite sets of variables.
description: 15 pages, Subjects: Mathematical Physics (math-ph); Representation Theory (math.RT); Exactly Solvable and Integrable Systems (nlin.SI)
Near-unity quantum yield from carbon nanotube excitons coupled to plasmonic nanocavities
Creators: name: Luo, Yue
name: Ahmadi, Ehsaneh D.
name: Shayan, Kamran
name: Ma, Yichen
name: Mistry, Kevin S.
name: Zhang, Changjian
name: Hone, James
name: Blackburn, Jeffrey L.
name: Strauf, Stefan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Single-walled carbon nanotubes (SWCNTs) are promising absorbers and emitters to enable novel photonic and optoelectronic applications but are also known to severely suffer from low optical quantum yields. Here we demonstrate SWCNTs excitons coupled to plasmonic nanocavities reaching deeply into the Purcell regime with FP=234 (average FP=76), near unity quantum yields of 70% (average 41%), and a photon emission rate of 1.7 MHz into the first lens. The measured ultra-narrow exciton linewidth (18 micro eV) implies furthermore generation of indistinguishable single photons from a SWCNT. To demonstrate utility beyond quantum light sources we show that nanocavity-coupled SWCNTs perform as single-molecule thermometers detecting plasmonically induced heat (Delta T=150K) in a unique interplay of excitons, phonons, and plasmons at the nanoscale.
description: 17 pages, 5 figures
Pew Research Center: U.S. Latino Religion May 2013 Survey
Creators: name: Pew Research Center
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: Prefer Hispanic or Latino to refer to people of Hispanic or Latino descent (1); heritage or county from (1); country born in (1); years lived in United States (1); denomination or church (1); religious service attendance (3); life satisfaction (1); life better or worse in next ten years (1); churches stay out of politics (1); smaller/bigger government (1); gay and lesbian marriage (1); abortion (1); most important Hispanic/Latino leader in country (2); effect of undocumented immigration on Hispanics/Latinos already living in United States (1); Hispanic race and ethnicity (3); typical American (1); volunteer activity in past 12 months (3); religious services in Spanish (3); religious services with Hispanic/Latino religious leaders (2); religious services where other people are Hispanic/Latino (2); ties to countries in Latin America through money or missionaries (1); leadership in religious institutions (4); type of Christianity (2); importance of religion to your life (1); faith practices (4); confession (1); crucifix or other religious objects (1); pray to specific figures (3); religious texts written by men or the word of God (1); holy book should be taken literally (1); bread and wine actually become body and blood of Christ [transubstantiation] (1); if enough people were brought to Christ social ills would take care of themselves (1); Mary is virgin mother of God (1); Jesus Christ return to earth in your lifetime (1); wealth, good health to believers who have deep faith (1); male leadership role in family (3); Pope Francis (2); Catholic Church welcoming to new immigrants (1); Catholic Church sex abuse scandal (1); Catholic Church reforms (4); religious experiences (6); belief in, experiences with spirits or magic (10); popular or folk saints (2); change in religion (14); English fluency (2); Spanish fluency (2); registered to vote (1).
Resonant spin transfer torque nano-oscillators
Creators: name: Sharma, Abhishek
name: Tulapurkar, Ashwin A
name: Muralidharan, Bhaskaran
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Spin transfer torque nano-oscillators are potential candidates for replacing the traditional inductor based voltage controlled oscillators in modern communication devices. Typical oscillator designs are based on trilayer magnetic tunnel junctions which are disadvantaged by low power outputs and poor conversion efficiencies. In this letter, we theoretically propose to use resonant spin filtering in pentalayer magnetic tunnel junctions as a possible route to alleviate these issues and present device designs geared toward a high microwave output power and an efficient conversion of the d.c. input power. We attribute these robust qualities to the resulting non-trivial spin current profiles and the ultra high tunnel magnetoresistance, both arising from resonant spin filtering. The device designs are based on the nonequilibrium Green's function spin transport formalism self-consistently coupled with the stochastic Landau-Lifshitz-Gilbert-Slonczewski's equation and the Poisson's equation. We demonstrate that the proposed structures facilitate oscillator designs featuring a large enhancement in microwave power of around $775\%$ and an efficiency enhancement of over $1300\%$ in comparison with typical trilayer designs. We also rationalize the optimum operating regions via an analysis of the dynamic and static device resistances. This work sets stage for pentalyer spin transfer torque nano-oscillator device designs that extenuate most of the issues faced by the typical trilayer designs.
description: 9 pages, 10 figures and Supplementary Material
Black hole as a magnetic monopole within exponential nonlinear electrodynamics
Creators: name: Kruglov, S. I.
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We perform the gauge covariant quantization of the exponential model of nonlinear electrodynamics. Magnetically charged black holes, in the framework of our model are considered, and the regular black hole solution is obtained in general relativity. The asymptotic black hole solution at $r\rightarrow \infty$ is found. We calculate the magnetic mass of the black hole and the metric function which are expressed via the parameter $β$ of the model and the magnetic charge. The thermodynamic properties and thermal stability of regular black holes are analysed. We calculate the Hawking temperature of black holes and their heat capacity at the constant magnetic charge. We find a point where the temperature changes the sign that corresponds to the first-order phase transition. It is shown that at critical point, where the heat capacity diverges, there is a phase transition of the second-order. We obtain the parameters of the model when the black hole is stable.
description: 19 pages, 4 figures
Additional file 4: of Anti-inflammatory cellular targets on neutrophils elucidated using a novel cell migration model and confocal microscopy: a clinical supplementation study
Creators: name: T. Smith
name: L. Engelbrecht
name: C. Smith
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Hematology

description: Representative flow cytometry scatter plots for the analysis of macrophage phenotype marker expression. (DOCX 203Â kb)
How the cluster environment affects the baryon cycle
Creators: name: Zabel, Nikki
Publisher: name: Zenodo
Year: 2020

description: The effect of environment on the baryon cycle is a crucial area of research in modern day astrophysics. It has been known for some time that galaxies in cluster environments have smaller atomic gas reservoirs than their counterparts in the field. There are several environmental processes that can remove this gas from galaxies and deposit it into the intra-cluster medium. These include galaxy-galaxy interactions, ram pressure stripping, and tidal interactions. Whether these environmental processes also affect the more tightly bound (and centrally distributed) molecular gas is much less obvious. Because molecular gas is the direct fuel for star formation, the effects of the cluster environment on this phase of the ISM has immediate consequences for the star formation rates within the host galaxy. If molecular gas is indeed directly affected by the cluster environment, this has important implications for the quenching of star formation in cluster galaxies and, with ~40% of the galaxies living in groups or clusters, for galaxy evolution as a whole. The ALMA Fornax Cluster Survey is a complete survey of all 30 galaxies in the Fornax cluster across the Hubble sequence that appear to host a cold ISM (based on HI and dust observations). The Fornax cluster is one of the nearest galaxy clusters (at ~17 Mpc) and is therefore an ideal laboratory to study the effects of the cluster environment on the gaseous reservoirs of its member galaxies. CO(1 – 0) was observed as a proxy for the cold molecular gas, allowing us to create resolved maps of its morphology and kinematics, and calculate H2 masses and deficiencies (compared to field galaxies). The combination of these data with Hα maps from MUSE allows us to investigate whether these cluster galaxies follow the Kennicutt-Schmidt relation, and to make detailed maps (~250 kpc scales) of depletion times within these galaxies. I will show that the tightly bound molecular ISM is indeed directly affected by the cluster environment, especially in low mass galaxies. Ram pressure stripping/tidal interactions are found to be removing cold gas from these objects, forming spectacular tails in some instances, and directly affecting the star formation efficiencies. The detection of these disturbed molecular gas reservoirs reveals the importance of the cluster environment, which is affecting the baryon cycle directly, even when considering the tightly bound molecular gas phase.
A Multi-Ringed, Modestly-Inclined Protoplanetary Disk around AA Tau
Creators: name: Loomis, Ryan A.
name: Öberg, Karin I.
name: Andrews, Sean M.
name: MacGregor, Meredith A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: AA Tau is the archetype for a class of stars with a peculiar periodic photometric variability thought to be related to a warped inner disk structure with a nearly edge-on viewing geometry. We present high resolution ($\sim$0.2") ALMA observations of the 0.87 and 1.3~mm dust continuum emission from the disk around AA Tau. These data reveal an evenly spaced three-ringed emission structure, with distinct peaks at 0.34", 0.66", and 0.99", all viewed at a modest inclination of 59.1$^{\circ}\pm$0.3$^{\circ}$ (decidedly not edge-on). In addition to this ringed substructure, we find non-axisymmetric features including a `bridge' of emission that connects opposite sides of the innermost ring. We speculate on the nature of this `bridge' in light of accompanying observations of HCO$^+$ and $^{13}$CO (J=3--2) line emission. The HCO$^+$ emission is bright interior to the innermost dust ring, with a projected velocity field that appears rotated with respect to the resolved disk geometry, indicating the presence of a warp or inward radial flow. We suggest that the continuum bridge and HCO$^+$ line kinematics could originate from gap-crossing accretion streams, which may be responsible for the long-duration dimming of optical light from AA Tau.
description: Accepted for publication in ApJ, 9 pages, 7 figures
A thermodynamic point of view on dark energy models
Creators: name: Cardone, Vincenzo F.
name: Radicella, Ninfa
name: Troisi, Antonio
Publisher: name: arXiv
Year: 2016
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We present a conjugate analysis of two different dark energy models investigating both their agreement with recent data and their thermodynamical properties. The successful match with the data allows to both constrain the model parameters and characterize their kinematical properties. As a novel step, we exploit the strong connection between gravity and thermodynamics to further check models viability by investigating their thermodynamical quantities. In particular, we study whether the cosmological scenario fulfills the generalized second law of thermodynamics and, moreover, we contrast the two model asking whether the evolution of the total entropy is in agreement with the expectation for a closed system. As a general result, we discuss whether thermodynamic constraints can be a valid complementary way to both constrain dark energy models and differentiate among rival scenarios.
description: 23 pages, 8 figures