cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Comments on environmental effects in the origin of angular momenta in galaxies
Creators: name: Panko, Elena
name: Pajowska, Paulina
name: Godlowski, Wlodzimierz
name: Flin, Piotr
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We examine the orientations of galaxies in 43 rich Abell galaxy clusters belonging to superclusters and containing at least 100 members in the considered area as a function of supercluster multiplicity. It is found that the orientation of galaxies in the analyzed clusters is not random and the alignment decreases with supercluster richness, although the effect is statistically significant only for azimuthal angles. The dependence of galaxy alignment on cluster location inside or outside a supercluster and on supercluster multiplicity clearly shows the importance of environmental effects on the origin of galaxy angular momenta. The comparison with alignment of galaxies in a sample of rich Abell clusters not belonging to superclusters is made too.
description: accepted in Odessa Astronomical Publications 2012 vol.25 p.21
Quark-Lepton Mass Relation in a Realistic A4 Extension of the Standard Model
Creators: name: King, S. F.
name: Morisi, S.
name: Peinado, E.
name: Valle, J. W. F.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose a realistic A4 extension of the Standard Model involving a particular quark-lepton mass relation, namely that the ratio of the third family mass to the geometric mean of the first and second family masses are equal for down-type quarks and charged leptons. This relation, which is approximately renormalization group invariant, is usually regarded as arising from the Georgi-Jarlskog relations, but in the present model there is no unification group or supersymmetry. In the neutrino sector we propose a simple modification of the so called Zee-Wolfenstein mass matrix pattern which allows an acceptable reactor angle along with a deviation of the atmospheric and solar angles from their bi-maximal values. Quark masses, mixing angles and CP violation are well described by a numerical fit.
description: 9 pages, 3 figures, version published in Phys. Lett. B
Additional file 2 of Syrian medical students’ acceptance of peer physical examination and its associating factors: a cross-sectional study
Creators: name: Soqia, Jameel
name: Shamaa, Mohamad Ashraf
name: Alhomsi, Dima
name: Yakoub-Agha, Laila
name: Alameer, Mhd Basheer
name: Alhomsi, Rawan
name: Hakok, Mohmad Nour
name: Khalil, Rim
name: Zaitouna, Mazen
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 2.
ANN Validation of Biodiesel Synthesis Optimization using Heterogeneous Catalyst (SiO2)
Creators: name: Patil, Satish A.
name: R. R. Arakerimath
Publisher: name: Zenodo
Year: 2021
Subjects: Transesterification
biodiesel
SiO2
Heterogeneous catalyst

description: Biodiesel is a renewable, ecofriendly fuel that can provide comparable engine performance. Karanja oil is made in this experiment using a transesterification process with SiO2 as a heterogeneous catalyst. It is investigated utilising five separate parameters and their respective levels. The orthogonal arrays are fixed using Minitab, and the Taguchi method is utilised to study the interaction impact for the transesterification reaction. Molar ratio, catalyst concentration, reaction temperature, reaction time, and stirring speed are the five variables that affect biodiesel yield. The impact of these variables has been investigated on a limited scale. Experimentally biodiesel yield obtained is 77% at optimum conditions are 20% molar ratio, 3% SiO2 catalyst addition, 65ºC reaction temperature, 180 min reaction time and 500 rpm stirring speed. Minitab results are compared here with ANN results using script by analytically as well as graphically.
Additional file 3 of Enhancing potential impact of hospital discharge interventions for patients with COPD: a qualitative systematic review
Creators: name: Nygård, Torbjørn
name: Wright, David
name: Nazar, Hamde
name: Haavik, Svein
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 3.
Dynamics of test particles in thin-shell wormhole spacetimes
Creators: name: Diemer, V.
name: Smolarek, E.
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Geodesic motion in traversable Schwarzschild and Kerr thin-shell wormholes constructed by the cut-and-paste method introduced by Visser (1989 Nucl. Phys. B 328 203; 1995 Wormholes: from Einstein to Hawking (Woodbury, MN: American Institute of Physics)) is studied. The orbits are calculated exactly in terms of elliptic functions and visualized with the help of embedding diagrams.
description: 14 pages, 9 Figs
Power-law dependence of the optical conductivity observed in the quantum spin-liquid compound κ-(BEDT-TTF)2Cu2(CN)3
Creators: name: Elsasser, Sebastian
name: Wu, Dan
name: Dressel, Martin
name: Schlueter, John A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The Mott-insulator κ-(BEDT-TTF)_2Cu_2(CN)_3 is the prime candidate of a quantum spin liquid with puzzling magnetic properties. Our THz and infrared investigations reveal that also the charge dynamics does not follow the expectations for a Mott insulator. The frequency-dependent conductivity exhibits a power-law behavior $σ_1(ω)\propto ω^n$ that grows stronger as the temperature decreases and extends all the way through the far-infrared. With $n\approx 0.8$ to 1.5 we obtain a significantly smaller exponent than predicted by Ng and Lee [Phys. Rev. Lett. {\bf 99}, 156402 (2007)]. We suggest fluctuations becomes important in the spin-liquid state and couple to the electrodynamic properties differently compared to the antiferromagnetic Mott insulator κ-(BEDT-TTF)_2Cu[N(CN)_2]Cl. We discuss the various possibilities of how charge fluctuations are influenced by the presence or absence of magnetic order.
description: 7 pages, 8 figures
Additional file 4 of Enhancing potential impact of hospital discharge interventions for patients with COPD: a qualitative systematic review
Creators: name: Nygård, Torbjørn
name: Wright, David
name: Nazar, Hamde
name: Haavik, Svein
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 4.
Additional file 2 of Post-warming culture of human vitrified blastocysts with prolactin improves trophoblast outgrowth
Creators: name: Ezoe, Kenji
name: Fujiwara, Nanoha
name: Miki, Tetsuya
name: Kato, Keiichi
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Plant Biology

description: Additional file 2: Table 1. TaqMan Gene Expression Assay used for quantification of mRNA expression. Table 2. Multiple linear regression analysis coefficients for outgrowth area.
The First Periodic Table for Elementary Particles
Creators: name: Lighthouse, Richard
Publisher: name: Zenodo
Year: 2014
Subjects: cosmology
elementary particles
supersymmetry
CERN
1024-QAM
Blinking universe
Quantum gravity

description: This short technical paper presents a new standard model for Elementary Particles. All elementary particle masses are related by simple math. This math is similar to the math used for wifi signals and it is called 1024-QAM. The 1024-QAM table graphically displays how all elementary particles are related, similar to the Standard Periodic Table in chemistry. If we line up all of the particle masses in order, we find there are a number of "gaps." These are called the mass gaps, and they line up perfectly with 1024-QAM, which fits the sequence.  Supersymmetry (SUSY) is also found to occur with 1024-QAM. Mass Groups 1 thru 8 have heavyweight counterparts which are found in Mass Groups 9 thru 16.  4 new particles are predicted to be discovered between 0.7 to 15 TeV. Also, 4 new particles are predicted to be discovered between 30 to 200 TeV. 
Numerous other new particles are predicted using 1024-QAM. The only possible explanation for elementary particles to match a QAM pattern, is due to a blinking or discrete universe. This ebook provides compelling evidence that our universe is literally blinking, off and on. This blinking frequency is about 1.1 THz.
This author challenges scientists in the particle physics field to provide a better model than 1024-QAM, that will fit the "mass gaps." I suggest starting with a QAM model and see what format you think will best fit the experimental data that is already available. In my opinion, the data to support 1024-QAM is already available at CERN, Berkeley, Fermi Lab, Brookhaven, Perimeter Institute, and Stanford. No expensive, new experiment will need to be run.
Connectivity-Driven Coherence in Complex Networks
Creators: name: Pereira, Tiago
name: Eroglu, Deniz
name: Bagci, G. B.
name: Tirnakli, U.
name: Jensen, Henrik J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences
subject: 34D06, 05C82

description: We study the emergence of coherence in complex networks of mutually coupled non-identical elements. We uncover the precise dependence of the dynamical coherence on the network connectivity, on the isolated dynamics of the elements and the coupling function. These findings predict that in random graphs, the enhancement of coherence is proportional to the mean degree. In locally connected networks, coherence is no longer controlled by the mean degree, but rather on how the mean degree scales with the network size. In these networks, even when the coherence is absent, adding a fraction s of random connections leads to an enhancement of coherence proportional to s. Our results provide a way to control the emergent properties by the manipulation of the dynamics of the elements and the network connectivity.
description: 4 pages, 2 figures
Analysing vote-choice in a multinational state: national identity and territorial differentiation in the 2016 Brexit vote
Creators: name: Henderson, Ailsa
name: Poole, Ed Gareth
name: Jones, Richard Wyn
name: Wincott, Daniel
name: Larner, Jac
name: Jeffery, Charlie
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Striking territorial variations in the 2016 Brexit referendum are neglected in the explanatory literature, a gap our analysis of the British Election Study (BES) helps to fill. Rather than modelling Britain as one political system, we present parallel models for England, Scotland and Wales. Typical in other multinational states, this approach is innovative for ‘British politics’. The analysis shows different variables help to explain Leave support in England, Scotland and Wales. To analyse complex multilevel national identities, we develop a relative territorial identity (RTI) measure. The measure shows that those who prioritize their territorial identity in England tended to vote Leave, while the opposite is true in Wales and Scotland. The performance of this RTI measure helps to explain territorial differentiation in the 2016 Brexit vote.
Additional file 1 of A comparison of international modelling methods to evaluate health economics of colorectal cancer screening: a systematic review protocol
Creators: name: Adair, Olivia
name: McFerran, Ethna
name: Owen, Tracy
name: McKee, Christine
name: Lamrock, Felicity
name: Lawler, Mark
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Science Policy

description: Additional file 1. PRISMA-P Document 2015. PRISMA-P document is used to make the peer review process efficient and strengthen the quality of reporting.
Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron-Like SH-SY5Y and Microglia-Like BV2
Creators: name: Crews, Fulton T.
name: Lawrimore, Colleen J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: BACKGROUND: Ethanol (EtOH) consumption leads to an increase of proinflammatory signaling via activation of Toll-like receptors (TLRs) such as TLR3 and TLR4 that leads to kinase activation (ERK1/2, p38, TBK1), transcription factor activation (NFκB, IRF3), and increased transcription of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6. This immune signaling cascade is thought to play a role in neurodegeneration and alcohol use disorders. While microglia are considered to be the primary macrophage in brain, it is unclear what if any role neurons play in EtOH-induced proinflammatory signaling.

METHODS: Microglia-like BV2 and retinoic acid-differentiated neuron-like SH-SY5Y were treated with TLR3 agonist Poly(I:C), TLR4 agonist lipopolysaccharide (LPS), or EtOH for 10 or 30 minutes to examine proinflammatory immune signaling kinase and transcription factor activation using Western blot, and for 24 hours to examine induction of proinflammatory gene mRNA using RT-PCR.

RESULTS: In BV2, both LPS and Poly(I:C) increased p-ERK1/2, p-p38, and p-NFκB by 30 minutes, whereas EtOH decreased p-ERK1/2 and increased p-IRF3. LPS, Poly(I:C), and EtOH all increased TNF-α and IL-1β mRNA, and EtOH further increased TLR2, 7, 8, and MD-2 mRNA in BV2. In SH-SY5Y, LPS had no effect on kinase or proinflammatory gene expression. However, Poly(I:C) increased p-p38 and p-IRF3, and increased expression of TNF-α, IL-1β, and IL-6, while EtOH increased p-p38, p-IRF3, p-TBK1, and p-NFκB while decreasing p-ERK1/2 and increasing expression of TLR3, 7, 8, and RAGE mRNA. HMGB1, a TLR agonist, was induced by LPS in BV2 and by EtOH in both cell types. EtOH was more potent at inducing proinflammatory gene mRNA in SH-SY5Y compared with BV2.

CONCLUSIONS: These results support a novel and unique mechanism of EtOH, TLR3, and TLR4 signaling in neuron-like SH-SY5Y and microglia-like BV2 that likely contributes to the complexity of brain neuroimmune signaling.
Information support of organizational and managerial activities as a factor of competition
Creators: name: SHEDYAKOV, V. E.
Publisher: name: Zenodo
Year: 2023

description: The subject of the study is information support of the organizational and managerial process.
The purpose of writing the article is to consider the place and role of establishing information
services for the organizational and managerial process in order to increase the competitiveness of
subjects of economy.
Methodology for the study are works on the factors of competitiveness, socio–economic
efficiency, organizational and managerial relations and information channels. And the information base
of the research consists of regulations, domestic and foreign publications, research on the content of
international economic relations, the direction and nature of megatrends in world development, the role
of transition periods, the ratio of strategy and tactics in making organizational and managerial decisions.
Results of the work – a study was made of the range of effectiveness of management information
support in the context of increasing the level of competitiveness of a business entity.
Conclusions. An indispensable attribute of the basis of competitiveness is organizational and
managerial efficiency, and its prerequisite is information support. The ability to see probable problems
«in advance» and determine the most productive ways to prevent it (localize, overcome) is the result
of talent, knowledge, and experience. The need to rely both on the optimization of one's own team
and on external command and individual connections (competitive / adversarial and partnership/
cooperative) is localized in the managerial contours of self–government and coordination. Accordingly,
information training and methodological literacy of business participants are necessary prerequisites
for successful security and development.
Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease
Creators: name: Naz, Mufassra
name: Priami, Corrado
name: Doshi, Jimit
name: Krause, Roland
name: Kong, Dehan
name: Sotiras, Aristeidis
name: Mangravite, Lara M.
name: Stolovitzky, Gustavo
name: Sabelnykova, Veronica Y.
name: Chaibub Neto, Elias
name: Oyang, Yen-Jen
name: Hong, Ming-Yi
name: Zhu, Shanfeng
name: Narayan, Manjari
name: Logsdon, Benjamin A.
name: Weiner, Michael W.
name: Lovestone, Simon
name: Anghel, Catalina
name: Tung, Yi-An
name: Xiao, Guanghua
name: Iyappan, Anandhi
name: Gan, Jessica
name: Dillenberger, Donna
name: Klein, Arno
name: Kauwe, John S.K.
name: Tateo, Andrea
name: Simmons, Andrew
name: Guan, Yuanfang
name: Bellotti, Roberto
name: Bennett, David A.
name: Chien, Ting-Ying
name: Lalonde, Emilie
name: Chen, Beibei
name: Tangaro, Sabina
name: Glaab, Enrico
name: Duma, Denise
name: Davatzikos, Christos
name: Hwang, Jinseub
name: Das, Sudeshna
name: Fardo, David W.
name: Ma, Tsung-Wei
name: Boutros, Paul C.
name: Fröhlich, Holger
name: Katsumata, Yuriko
name: Xu, Jia
name: Yang, Hojin
name: Huang, Chao
name: Zhu, Hongtu
name: Clark, Tim
name: Lin, Xihui
name: Allen, Genevera I.
name: Lee, Eunjee
name: Ibrahim, Joseph
name: Nurtdinov, Ramil N.
name: Livingstone, Julie
name: Friend, Stephen H.
name: Pawitan, Yudi
name: St George-Hyslop, Peter
name: Errico, Rosangela
name: Boehme, Kevin L.
name: Erus, Guray
name: Xie, Lei
name: Amoroso, Nicola
name: Zhu, Fan
name: Deng, Jieyao
name: Green, Robert C.
name: Liu, Zhandong
name: Senger, Philipp
name: Bare, Christopher J.
name: Caloian, Cristian
name: Zhan, Xiaowei
name: Peng, Shengwen
name: Maxwell, Taylor J.
name: Praveen, Paurush
name: Ghosh, Satrajit S.
name: Namasivayam, Aishwarya
name: Malhotra, Ashutosh
name: Lauria, Mario
name: Dobson, Richard J.B.
name: Everett, Evan
name: Caberlotto, Laura
name: Varol, Erdem
name: Zhou, Yunyun
name: Nagorski, John
name: Campbell, Frederick
name: Piccolo, Stephen R.
name: Xie, Yang
name: Inglese, Paolo
name: Beaton, Derek
name: Chen, Chien-Yu
name: Chang, Yu-Chuan
name: Norman, Thea C.
name: Vradenburg, George
name: Dong, Qilin
name: Merrill, Emily
name: Balagurusamy, Venkat
name: Tustison, Nicholas J.
name: Shen, Xia
name: Newhouse, Stephen J.
name: Jiang, Qijia
name: Peters, Mette A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Identifying accurate biomarkers of cognitive decline is essential for advancing early diagnosis and prevention therapies in Alzheimer’s Disease. The Alzheimer’s Disease DREAM Challenge was designed as a computational crowdsourced project to benchmark the current state-of-the-art in predicting cognitive outcomes in Alzheimer’s Disease based on high-dimensional, publicly available genetic and structural imaging data. This meta-analysis failed to identify a meaningful predictor developed from either data modality, suggesting that alternate approaches should be considered for to prediction of cognitive performance.
Additional file 1 of Comparison of inequality in utilization of postnatal care services between Bangladesh and Pakistan: Evidence from the Demographic and Health Survey 2017–2018
Creators: name: Misu, Farjana
name: Alam, Khurshid
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
The brightest pure-H ultracool white dwarf
Creators: name: Catalan, S.
name: Tremblay, P. -E.
name: Pinfield, D. J.
name: Smith, L. C.
name: Zhang, Z. H.
name: Napiwotzki, R.
name: Marocco, F.
name: Day-Jones, A. C.
name: Gomes, J.
name: Forde, K. P.
name: Lucas, P. W.
name: Jones, H. R. A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report the identification of LSR J0745+2627 in the United Kingdom InfraRed Telescope Infrared Deep Sky Survey (UKIDSS) Large Area Survey (LAS) as a cool white dwarf with kinematics and age compatible with the thick-disk/halo population. LSR J0745+2627 has a high proper motion (890 mas/yr) and a high reduced proper motion value in the J band (H_J=21.87). We show how the infrared-reduced proper motion diagram is useful for selecting a sample of cool white dwarfs with low contamination. LSR J0745+2627 is also detected in the Sloan Digital Sky Survey (SDSS) and the Wide-field Infrared Survey Explorer (WISE). We have spectroscopically confirmed this object as a cool white dwarf using X-Shooter on the Very Large Telescope. A detailed analysis of its spectral energy distribution reveals that its atmosphere is compatible with a pure-H composition model with an effective temperature of 3880+-90 K. This object is the brightest pure-H ultracool white dwarf (Teff<4000 K) ever identified. We have constrained the distance (24-45 pc), space velocities and age considering different surface gravities. The results obtained suggest that LSR J0745+2627 belongs to the thick-disk/halo population and is also one of the closest ultracool white dwarfs.
description: 5 pages, 7 figures, accepted for publication in A&A Letters
Effect of distribution of stickers along backbone on temperature-dependent structural properties in associative polymer solutions
Creators: name: Han, X. -G.
name: Zhang, X. -F.
name: Ma, Y. -H.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Effect of distribution of stickers along the backbone on structural properties in associating polymer solutions is studied using self-consistent field lattice model. Only two inhomogeneous morphologies, i.e., microfluctuation homogenous (MFH) and micelle morphologies, are observed. If the system is cooled, the solvent content within the aggregates decreases. When the spacing of stickers along the backbone is increased the temperature-dependent range of aggregation in MFH morphology and half-width of specific heat peak for homogenous solutions-MFH transition increase, and the symmetry of the peak decreases. However, with increasing spacing of stickers, the above three corresponding quantities related to micelles behave differently. It is demonstrated that the broad nature of the observed transitions can be ascribed to the structural changes which accompany the replacement of solvents in aggregates by polymer, which is consistent with the experimental conclusion. It is found that different effect of spacing of stickers on the two transitions can be interpreted in terms of intrachain and interchain associations.
description: 10 pages, 4 figures. arXiv admin note: text overlap with arXiv:1202.4595
Brexit disruption and transborder leadership in Europe
Creators: name: Gibney, John
name: Liddle, Joyce
name: Shutt, John
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The turbulence of Brexit threatens to undermine England–European Union (EU) transborder cooperation at the subnational scale. This paper discusses the lived experience of city and regional leaders involved in developing cross-European cooperation during the early phase of the Brexit ‘project’. It contributes to the idea of relational leadership as a framing device for studying leadership in transborder cooperation in the England–EU subnational setting, and surfaces challenges faced by subnational leaders in transborder cooperation during significant policy turbulence. Two main findings of the research have wider relevance for emerging city and regional (place) leadership theory and practice. First, the unanticipated shock caused by Brexit to the supra-national policy environment is impacting significantly on subnational leaders’ ability to maintain good transborder working relationships; and second, continuing non-prejudicial dialogue and meaningful conversations between subnational partners are an antidote to the negative legacies of such policy disruption.
Initial genetic dissection of serum neuroactive steroids following chronic intermittent ethanol across BXD mouse strains
Creators: name: Williams, Robert W.
name: O'Buckley, Todd K.
name: Lopez, Marcelo F.
name: Miles, Michael F.
name: Porcu, Patrizia
name: Becker, Howard C.
name: Morrow, A. Leslie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Neuroactive steroids modulate alcohol’s impact on brain function and behavior. Ethanol exposure alters neuroactive steroid levels in rats, humans, and some mouse strains. We conducted an exploratory analysis of the neuroactive steroids (3α,5α)-3-hydroxypregnan-20-one (3α,5α-THP), (3α,5α)-3,21-dihydroxypregnan-20-one (3α,5α-THDOC), and pregnenolone across 126–158 individuals and 19 fully inbred strains belonging to the BXD family, which were subjected to air exposure, or chronic intermittent ethanol (CIE) exposure. Neuroactive steroids were measured by gas chromatography-mass spectrometry in serum following five cycles of CIE or air exposure (CTL). Pregnenolone levels in CTLs range from 272 to 578 pg/mL (strain variation of 2.1-fold with p = 0.049 for strain main effect), with heritability of 0.20 ± 0.006 (SEM), whereas in CIE cases values range from 304 to 919 pg/mL (3.0-fold variation, p = 0.007), with heritability of 0.23 ± 0.005. 3α,5α-THP levels in CTLs range from 375 to 1055 pg/mL (2.8-fold variation, p = 0.0007), with heritability of 0.28 ± 0.01; in CIE cases they range from 460 to 1022 pg/mL (2.2-fold variation, p = 0.004), with heritability of 0.23 ± 0.005. 3α,5α-THDOC levels in CTLs range from 94 to 448 pg/mL (4.8-fold variation, p = 0.002), with heritability of 0.30 ± 0.01, whereas levels in CIE cases do not differ significantly. However, global averages across all BXD strains do not differ between CTL and CIE for any of the steroids. 3α,5α-THDOC levels were lower in females than males in both groups (CTL −53%, CIE −55%, p < 0.001). Suggestive quantitative trait loci are identified for pregnenolone and 3α,5α-THP levels. Genetic variation in 3α,5α-THP was not correlated with two-bottle choice ethanol consumption in CTL or CIE-exposed animals. However, individual variation in 3α,5α-THP correlated negatively with ethanol consumption in both groups. Moreover, strain variation in neuroactive steroid levels correlated with numerous behavioral phenotypes of anxiety sensitivity accessed in GeneNetwork, consistent with evidence that neuroactive steroids modulate anxiety-like behavior.
Tensor hypercontraction: A universal technique for the resolution of matrix elements of local, finite-range $N$-body potentials in many-body quantum problems
Creators: name: Parrish, Robert M.
name: Hohenstein, Edward G.
name: Schunck, Nicolas F.
name: Sherrill, C. David
name: Martinez, Todd J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Nuclear Theory (nucl-th)
subject: Chemical Physics (physics.chem-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Configuration-space matrix elements of N-body potentials arise naturally and ubiquitously in the Ritz-Galerkin solution of many-body quantum problems. For the common specialization of local, finite-range potentials, we develop the eXact Tensor HyperContraction (X-THC) method, which provides a quantized renormalization of the coordinate-space form of the N-body potential, allowing for a highly separable tensor factorization of the configuration-space matrix elements. This representation allows for substantial computational savings in chemical, atomic, and nuclear physics simulations, particularly with respect to difficult "exchange-like" contractions.
description: Third version of the manuscript after referee's comments. In press in PRL. Main text: 4 pages, 2 figures, 1 table; Supplemental material (also included): 14 pages, 2 figures, 2 tables
Comparative effectiveness and safety of infliximab and adalimumab in patients with ulcerative colitis
Creators: name: Schilz,
name: Singh,
name: Shah,
name: Loftus,
name: Kappelman,
name: Heien,
name: Sangaralingham,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Real-world comparative benefits and risks of infliximab (IFX) and adalimumab (ADA) in patients with ulcerative colitis (UC) is unclear.
Component-resolved analysis of IgA, IgE, and IgG4 during egg OIT identifies markers associated with sustained unresponsiveness
Creators: name: Wright,
name: Dawson,
name: Henning,
name: Jones,
name: Sampson,
name: Leung,
name: Kulis,
name: Wood,
name: Stablein,
name: Lindblad,
name: Sicherer,
name: Vickery,
name: Orgel,
name: Burks,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: In a previously reported CoFAR study, 55 subjects with egg allergy underwent randomized, placebo-controlled egg oral immunotherapy (eOIT). Active treatment induced desensitization in most and sustained unresponsiveness (SU) in a smaller subset. We hypothesized that component-resolved analysis of IgE, IgG4, IgA, IgA1, and IgA2 may identify potential biomarkers of SU in OIT subjects.
Charge and spin supercurrents in triplet superconductor--ferromagnet--singlet superconductor Josephson junctions
Creators: name: Brydon, P. M. R.
name: Chen, Wei
name: Asano, Yasuhiro
name: Manske, Dirk
Publisher: name: arXiv
Year: 2013
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study the Josephson effect in a triplet superconductor--ferromagnet--singlet superconductor junction. We show that the interaction of tunneling Cooper pairs with the interface magnetization can permit a Josephson current at the lowest order of a tunneling Hamiltonian perturbation theory. Two conditions must be satisfied for this to occur: the magnetization of the ferromagnet has a component parallel to the ${\bf d}$-vector of the triplet superconductor, and the gaps of the superconductors have the same parity with respect to the interface momentum. The resulting charge current displays an unconventional dependence on the orientation of the magnetic moment and the phase difference. This is accompanied by a phase-dependent spin current in the triplet superconductor, while a phase-independent spin current is always present. The tunneling perturbation theory predictions are confirmed using a numerical Green's function method. An analytical treatment of a one-dimensional junction demonstrates that our conclusions are robust far away from the tunneling regime, and reveals signatures of the unconventional Josephson effect in the critical currents.
description: 14 pages, 10 figures, published version
Teutoburg-Forschung auf neuer Grundlage
Creators: name: Langewiesche, Friedrich
Publisher: name: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts
Year: 2018

description: -
description: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts, Bd. 28, Nr. 1/2 (1944-1950)
Global technological trends in the development of equipment systems for armored combat vehicles – tanks
Creators: name: SHABRANSKA, N. I.
Publisher: name: Zenodo
Year: 2023

description: The subject of the study is modern technological trends in the field of scientific and technical
developments in the direction of «Armored combat vehicles – tanks» in terms of equipment systems,
the analysis of which was carried out on the basis of research by the international patent database
Derwent Innovation.
The purpose of the research is to identify and form the most promising directions and sub–
directions on the subject of «Armored combat vehicles – tanks» in equipment systems.
Research methods. Systemic and analytical analysis, logical–structural, comparative.
Results of work. The study of the data of the international patent platform «Derwent Innovation»
made it possible to identify and form the most promising directions and sub–directions of patenting
in the military industry on the topic of «Armored combat vehicles – tanks» in terms of the equipment
system, the development and implementation of which in the military industry of Ukraine will enable the
effective distribution of resources and means.
The scope of the results. Economics and management of the national economy, methods and
mechanisms of regulation of economic processes and their efficiency, promising directions of the
development of the military–industrial complex (MIC).
Conclusions. Based on the results of the research, 6 directions and 11 sub–directions were
formed, which include: «sensor range» (sub–directions: «optical spectrum sensor»; «capacitive type
vibration sensor»); «dynamic armor of tanks» (subdirection «reactive armor»); «armor system» (sub–
directions: «composite armor with reduced weight»); «active protection system» (sub–directions:
«active ballistic protection system»; «protective seat for BBM»; «intelligent acoustic protection
system for armored vehicles»); «dynamic protection» (sub–directions: «three–level system of dynamic
protection of tanks»); «passive and active sensors» (sub–headings: «weapons and explosives detector
and detection method»; «collision avoidance system (TCAS)»).
An efficient Markov chain Monte Carlo algorithm for the surface code
Creators: name: Hutter, Adrian
name: Wootton, James R.
name: Loss, Daniel
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Minimum-weight perfect matching (MWPM) has been been the primary classical algorithm for error correction in the surface code, since it is of low runtime complexity and achieves relatively low logical error rates [Phys. Rev. Lett. 108, 180501 (2012)]. A Markov chain Monte Carlo (MCMC) algorithm [Phys. Rev. Lett. 109, 160503 (2012)] is able to achieve lower logical error rates and higher thresholds than MWPM, but requires a classical runtime complexity which is super-polynomial in L, the linear size of the code. In this work we present an MCMC algorithm that achieves significantly lower logical error rates than MWPM at the cost of a polynomially increased classical runtime complexity. For error rates p close to the threshold, our algorithm needs a runtime complexity which is increased by O(L^2) relative to MWPM in order to achieve a lower logical error rate. If p is below an L-dependent critical value, no increase in the runtime complexity is necessary any longer. For p->0, the logical error rate achieved by our algorithm is exponentially smaller (in L) than that of MWPM, without requiring an increased runtime complexity. Our algorithm allows for trade-offs between runtime and achieved logical error rates as well as for parallelization, and can be also used to correct in the case of imperfect stabilizer measurements.
description: 10 pages, 10 figures; v2: includes community feedback
Randomised clinical trial: exploratory phase 2 study of ONO-2952 in diarrhoea-predominant irritable bowel syndrome
Creators: name: Whitehead,
name: Nabata,
name: Sharpe,
name: Duffy,
name: Bruce,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: BACKGROUND: ONO-2952 is a novel and selective inhibitor of translocator protein 18 kDa that reduces stress-induced defecation and visceral hyperalgesia in rat models.

AIM: To evaluate the efficacy and safety of ONO-2952 in females with irritable bowel syndrome with diarrhoea in an exploratory proof-of-concept study.

METHODS: A randomised, double-blind, placebo-controlled study was conducted at 49 US centres. Two hundred subjects with irritable bowel syndrome with diarrhoea (Rome III criteria) were randomised to ONO-2952 20 mg, or 60 mg, or placebo. Subjects recorded irritable bowel syndrome symptoms daily during a 2-week baseline period, the 4-week treatment period and for 4 weeks post-treatment. The co-primary endpoints were change from baseline to week 4 in abdominal pain, stool consistency and stool frequency.

RESULTS: Improvements in irritable bowel syndrome symptoms were seen with ONO-2952 over placebo in per-protocol analyses for all three co-primary endpoints, but these did not reach statistical significance at the 5% level. The largest improvement was seen with ONO-2952 60 mg. ONO-2952 was well tolerated with a safety profile similar to that of placebo. Most adverse events were mild or moderate in severity and not treatment related.

CONCLUSION: ONO-2952 showed evidence of clinical efficacy in reducing irritable bowel syndrome-related symptoms in female subjects with irritable bowel syndrome with diarrhoea, and further evaluation is, therefore, warranted to assess its potential as a treatment for irritable bowel syndrome with diarrhoea (NCT01844180).
Health law and policy, devolution and Brexit
Creators: name: McHale, Jean
name: Speakman, Elizabeth M.
name: Hervey, Tamara
name: Flear, Mark
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: The National Health Service (NHS) was a critical symbolic issue in the European Union (EU) referendum. The practical ramifications of Brexit on UK patients, professionals, health research and public health are significant, with particular challenges in the devolved nations/jurisdictions. Whatever the form of Brexit, and future EU–UK relationship(s), these challenges will form a key part of health governance post-Brexit. A multilevel governance approach will help make sense of this new regulatory terrain, and its effects for health and the NHS. It is important to understand, raise awareness of and navigate the different Brexit effects for health in the devolved nations/jurisdictions, and the different Brexit effects for different aspects of health and its governance; the broader economic, social and cultural contexts of Brexit and their indirect implications for health; and how legal responsibilities for healthcare are a poor fit with the emerging realities of managing Brexit.
Higher spin black hole entropy in three dimensions
Creators: name: Perez, Alfredo
name: Tempo, David
name: Troncoso, Ricardo
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: A generic formula for the entropy of three-dimensional black holes endowed with a spin-3 field is found, which depends on the horizon area A and its spin-3 analogue, given by the reparametrization invariant integral of the induced spin-3 field at the spacelike section of the horizon. From this result it can be shown that the absolute value of the spin-3 analogue of the area has to be bounded from above by A/3^(1/2). The entropy formula is constructed by requiring the first law of thermodynamics to be fulfilled in terms of the global charges obtained through the canonical formalism. For the static case, in the weak spin-3 field limit, our expression for the entropy reduces to the result found by Campoleoni, Fredenhagen, Pfenninger and Theisen, which has been recently obtained through a different approach.
description: 12 pages. Typos corrected. Matches published version
UK analysts’ and policy-makers’ perspectives on Brexit: challenges, priorities and opportunities for subnational areas
Creators: name: Billing, Chloe
name: McCann, Philip
name: Ortega-Argilés, Raquel
name: Sevinc, Deniz
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy

description: This paper explores the perspectives of expert analysts and policy-makers on the implications of Brexit for different parts of the UK economy. For local and regional areas, the need for such expert voices to be heard is urgent, given the fact that UK subnational and substate governance authorities have been effectively blocked out of all Brexit-related negotiations, and as such, are wholly unprepared for the post-Brexit realities. The issues discussed in this paper reflect the key themes that came out of four regional stakeholder participatory symposia organized by The UK in a Changing Europe (UKICE), which were held in Leeds, Birmingham, London and Edinburgh, and that focused on the Brexit-related economic and governance challenges for the different parts of the UK. These issues are examined in the light of the recent ‘levelling-up’ agenda prioritized by the UK government.
Additional file 2 of A comparison of international modelling methods to evaluate health economics of colorectal cancer screening: a systematic review protocol
Creators: name: Adair, Olivia
name: McFerran, Ethna
name: Owen, Tracy
name: McKee, Christine
name: Lamrock, Felicity
name: Lawler, Mark
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Science Policy

description: Additional file 2. MESH Search Terms. This document provides the MESH search terms that were included specifically in the MEDLINE database and altered to fit the other databases.
Additional file 2 of Comparison of inequality in utilization of postnatal care services between Bangladesh and Pakistan: Evidence from the Demographic and Health Survey 2017–2018
Creators: name: Misu, Farjana
name: Alam, Khurshid
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2
Vapnik-Chervonenkis density on indiscernible sequences, stability, and the maximum property
Creators: name: Johnson, Hunter R.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics
subject: 03C45

description: This paper presents some finite combinatorics of set systems with applications to model theory, particularly the study of dependent theories. There are two main results. First, we give a way of producing lower bounds on VC_ind-density, and use it to compute the exact VC_ind- density of polynomial inequalities, and a variety of geometric set families. The main technical tool used is the notion of a maximum set system, which we juxtapose to indiscernibles. In the second part of the paper we give a maximum set system analogue to Shelah's characterization of stability using indiscernible sequences.
description: 12 pages
Bathyferula Stahlschmidt, Lamy & Fraussen, 2012, new genus
Creators: name: Stahlschmidt, Peter
name: Lamy, Dominique
name: Fraussen, Koen
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Bathyferula

description: Bathyferula new genus
 Type species: Bathyferula delannoyei new species, by original designation.
 Diagnosis. Shell large, solid. Shape elongate, fusiform, with high spire and moderately elongate anterior canal, which is unnotched. Whorls convex, laterally flattened, with weak subsutural concavity. Spiral sculpture characterized by the presence of fine cords and a flattened subsutural cord. Axial sculpture consisting of short axial ribs on abapical part of upper whorls, becoming obsolete on penultimate and body whorls, with fine incremental lines covering the whole surface. Anal sinus regularly U-shaped.
 Remarks. The new genus is characterized by a large and rather heavy shell, a very slender shape, a long anterior canal, and the presence of a weak subsutural fold. Several Caribbean species assigned to Hindsiclava are similar in shape and in possessing a faint subsutural fold but bear a parietal callus and well developed axial sculpture (see Hindsiclava macilenta (Dall, 1889), Fig. 9). Darbya Bartsch, 1934, currently known only by the Puerto Rican type species D. lira Bartsch, 1934, differs in its relatively short anterior canal, its smaller size, its well developed axial sculpture and in having a parietal callus and a well developed columellar fold. There is also similarity to species usually included in Fusiturricula, but the latter genus is distinguished by its long anterior canal, the evenly spaced, well developed axial ribs, and the only very slightly developed subsutural fold. Several species of Leucosyrinx Dall, 1889 may also be mentioned for their somewhat similar shape and the presence of a similar anal sinus, though they differ from the new genus in having thin off-white shells and axial folds with peripheral tubercles. Moreover, a subsutural fold is not presented in Leucosyrinx. The genus Famelica Bouchet & Warén, 1980 resembles the new genus only superficially in shape and spiral sculpture but differs distinctly by the absence of a subsutural fold, the much smaller size and the very fragile shells. Etymology: Bathyferula new genus is derived from bathys (Greek), meaning “deep”, in combination with ferula (Latin) meaning “stake” or “rod”, which refers to the shell shape and colour resembling a stake of wood.
description: Published as part of Stahlschmidt, Peter, Lamy, Dominique & Fraussen, Koen, 2012, Bathyferula, a new Caribbean deep-water turrid genus (Gastropoda: Turroidea), with description of a large-sized new species, pp. 65-68 in Zootaxa 3158 on pages 65-66, DOI: 10.5281/zenodo.210592
Cardiovascular health among diverse Hispanics/Latinos: Hispanic Community Health Study/Study of Latinos (HCHS/SOL) results
Creators: name: Rodríguez, Carlos J.
name: Tarraf, Wassim
name: Heiss, Gerardo
name: Sacco, Ralph L.
name: Kizer, Jorge R.
name: Gallo, Linda C.
name: González, Hector M.
name: Hernandez, Rosalba
name: Daviglus, Martha L.
name: Davis, Sonia
name: Schneiderman, Neil
name: Kaplan, Robert C.
name: Talavera, Gregory A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Seven national 2020 Strategic Impact Goals for cardiovascular health (Life’s Simple 7 [LS7]) estimates for major ethnic/racial groups are available, but not for diverse Hispanics/Latinos. Herein, we describe and examine LS7 profiles of diverse Hispanic/Latino groups.