cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Interest and need for continuing medical education in pediatric complementary and integrative medicine: a cross-sectional survey from Switzerland
Creators: name: Huber, Benedikt M.
name: Rodondi, Pierre-Yves
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1.
Supplementary figure6a_vary_delta_clearance_noname from A touch of sleep: biophysical model of contact-mediated dormancy of archaea by viruses
Creators: name: Gulbudak, Hayriye
name: Weitz, Joshua S.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: The canonical view of the interactions between viruses and their microbial hosts presumes that changes in host and virus fate require the initiation of infection of a host by a virus. Infection may lead to the death of the host cell and release of viruses, to the elimination of the viral genome through cellular defense mechanisms, or the integration of the viral genome with the host as a chromosomal or extra-chromosomal element. Here we revisit this canonical view, inspired by recent experimental findings in which the majority of target host cells can be induced into a dormant state when exposed to either active or de-activated viruses, even when viruses are present at low relative titer. We propose that both the qualitative phenomena and the quantitative time-scales of dormancy induction are consistent with the hypothesis that cellular physiology can be altered by contact on the surface of host cells rather than strictly by infection. In order to test this hypothesis, we develop and study a biophysical model of contact-mediated dynamics involving virus particles and target cells. We show how virus particles can catalyze cellular transformations amongst many cells, even if they ultimately infect only one (or none). We also find that population-scale dormancy is robust to variation in the representation of model dynamics, including cell growth, death, and recovery.
Archaeology in Surrey 2003
Creators: name: Howe, Tony
name: Jackson, Gary
name: Maloney, Catharine
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 315-335
description: Brief notes of archaeological fieldwork carried out and chance finds made during the year in the administrative county of Surrey and in the southwest boroughs of Greater London, arranged in sections for each District or Borough, and by national grid reference within sections.
Banishing Bronchitis™ eBook PDF Free Download Shelly Manning
Creators: name: Shelly, Meril
Publisher: name: Zenodo
Year: 2024

description: "Banishing Bronchitis" by Shelly Manning is a holistic program designed to address bronchitis symptoms through natural and lifestyle interventions. Developed by an alternative health practitioner, the program focuses on understanding the root causes of bronchitis and suggests specific steps to reverse the condition. The approach includes quitting smoking, identifying and eliminating problematic foods, incorporating anti-inflammatory foods, regular exercise, and managing stress and sleep. The program is grounded in scientific research and offers benefits such as reduced coughing, improved breathing, better sleep, and increased energy. The pros include a natural approach, scientific alignment, user-friendly instructions, holistic impact, a money-back guarantee, and customer support. Cons include online availability, the need for commitment, and individual variations in results. The program is priced at $49 with a 60-day money-back guarantee. Overall, it provides a comprehensive and risk-free approach to managing bronchitis and improving overall health.
title: Social media analytics for future oriented policy making
Creators: name: Grubmüller, Verena
name: Götsch, Katharina
name: Krieger, Bernhard
Publisher: name: Universität Potsdam
Year: 2020

description: Research indicates that evidence-based policy making is most successful when public administrators refer to diversified information portfolios. With the rising prominence of social media in the last decade, this paper argues that governments can benefit from integrating this publically available, user-generated data through the technique of social media analytics (SMA). There are already several initiatives set up to predict future policy issues, e.g. for the policy fields of crisis mitigation or migrant integration insights. The authors analyse these endeavours and their potential for providing more efficient and effective public policies. Furthermore, they scrutinise the challenges to governmental SMA usage in particular with regards to legal and ethical aspects. Reflecting the latter, this paper provides forward-looking recommendations on how these technologies can best be used for future policy making in a legally and ethically sound manner.
description: Postprints der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe, 121
Supplementary figure6d_vary_delta_no_cell_death_no_virus_decay_noname from A touch of sleep: biophysical model of contact-mediated dormancy of archaea by viruses
Creators: name: Gulbudak, Hayriye
name: Weitz, Joshua S.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: The canonical view of the interactions between viruses and their microbial hosts presumes that changes in host and virus fate require the initiation of infection of a host by a virus. Infection may lead to the death of the host cell and release of viruses, to the elimination of the viral genome through cellular defense mechanisms, or the integration of the viral genome with the host as a chromosomal or extra-chromosomal element. Here we revisit this canonical view, inspired by recent experimental findings in which the majority of target host cells can be induced into a dormant state when exposed to either active or de-activated viruses, even when viruses are present at low relative titer. We propose that both the qualitative phenomena and the quantitative time-scales of dormancy induction are consistent with the hypothesis that cellular physiology can be altered by contact on the surface of host cells rather than strictly by infection. In order to test this hypothesis, we develop and study a biophysical model of contact-mediated dynamics involving virus particles and target cells. We show how virus particles can catalyze cellular transformations amongst many cells, even if they ultimately infect only one (or none). We also find that population-scale dormancy is robust to variation in the representation of model dynamics, including cell growth, death, and recovery.
Supplementary figure6e_vary_delta_no_cell_demography_no_virus_decay_noname from A touch of sleep: biophysical model of contact-mediated dormancy of archaea by viruses
Creators: name: Gulbudak, Hayriye
name: Weitz, Joshua S.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: The canonical view of the interactions between viruses and their microbial hosts presumes that changes in host and virus fate require the initiation of infection of a host by a virus. Infection may lead to the death of the host cell and release of viruses, to the elimination of the viral genome through cellular defense mechanisms, or the integration of the viral genome with the host as a chromosomal or extra-chromosomal element. Here we revisit this canonical view, inspired by recent experimental findings in which the majority of target host cells can be induced into a dormant state when exposed to either active or de-activated viruses, even when viruses are present at low relative titer. We propose that both the qualitative phenomena and the quantitative time-scales of dormancy induction are consistent with the hypothesis that cellular physiology can be altered by contact on the surface of host cells rather than strictly by infection. In order to test this hypothesis, we develop and study a biophysical model of contact-mediated dynamics involving virus particles and target cells. We show how virus particles can catalyze cellular transformations amongst many cells, even if they ultimately infect only one (or none). We also find that population-scale dormancy is robust to variation in the representation of model dynamics, including cell growth, death, and recovery.
Erbridge and the Merstham denns in Horley
Creators: name: Ellaby, Roger L
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 71-92
description: Document and map studies have led to what are thought to be the precise locations and boundaries of the Wealden denns of Merstham, later to become the tithing of Erbridge in Horley. Their identities allow a new translation for the appendix to the Merstham charter-bounds of AD 947 and an interpretation that suggests enclosure of much of the Low Weald around Horley had long been complete when the charter was written. The enclosure, into discrete administered denns, is argued to have been largely the work of Chertsey Abbey to better control the resources of a communal pasture previously belonging to a `federation' of settlements on the Downs and greensand to the north. Of the communal pasture that remained unenclosed (until the nineteenth century) the largest area became known as Thunderfield. Its relationship to the denns is explored and locations suggested for King Alfred's `royal vill' and a pagan `shrine' dedicated to Thunor. Includes
Supplementary figure6b_vary_delta_no_recovery_noname from A touch of sleep: biophysical model of contact-mediated dormancy of archaea by viruses
Creators: name: Gulbudak, Hayriye
name: Weitz, Joshua S.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: The canonical view of the interactions between viruses and their microbial hosts presumes that changes in host and virus fate require the initiation of infection of a host by a virus. Infection may lead to the death of the host cell and release of viruses, to the elimination of the viral genome through cellular defense mechanisms, or the integration of the viral genome with the host as a chromosomal or extra-chromosomal element. Here we revisit this canonical view, inspired by recent experimental findings in which the majority of target host cells can be induced into a dormant state when exposed to either active or de-activated viruses, even when viruses are present at low relative titer. We propose that both the qualitative phenomena and the quantitative time-scales of dormancy induction are consistent with the hypothesis that cellular physiology can be altered by contact on the surface of host cells rather than strictly by infection. In order to test this hypothesis, we develop and study a biophysical model of contact-mediated dynamics involving virus particles and target cells. We show how virus particles can catalyze cellular transformations amongst many cells, even if they ultimately infect only one (or none). We also find that population-scale dormancy is robust to variation in the representation of model dynamics, including cell growth, death, and recovery.
A Salvage Excavation near Reigate Priory with a note on a medieval seal die fro the Priory Park
Creators: name: Williams, David W
Publisher: name: Archaeology Data Service
Year: 2002

description: Surrey Archaeological Collections, 81, 171-174
description: A short excavation in 1990, in advance of development, revealed the line of a former path. Also detailed is a copper alloy medieval seal die discovered by metal detection in 1988. There is a note on the latter by Geoff Egan (174).
Excavation of late Saxon/early medieval deposits at Mitcham Vicarage, 21 Church Road, Mitcham
Creators: name: Ford, Steve
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 93-104
description: The report describes the archaeological excavation carried out in the rear gardens of Mitcham Vicarage. Two areas were opened, located on the basis of the results of an earlier evaluation. The main area (A) located several recut boundary ditches aligned east--west approximately parallel to Church Road, along with a small number of postholes, pits and a gully. The majority of the features were of late Saxon/early medieval and medieval date (eleventh--fourteenth centuries), with some late post-medieval (eighteenth century) and modern disturbance. The smaller area (B) was located to recover the remains of a horse burial found during the evaluation. Although this burial contained medieval pottery, the presence of other items, such as coal, and the form of the horseshoes, shows that it is late post-medieval in date. A small number of sherds of Roman pottery and a tegula fragment, and a single sherd of middle Saxon pottery, point to some activity of these periods in the vicinity, although not necessarily anything more than manuring of farmland. Specialist reports include
The Most Important Thing That's Probably Missing From Your Backyard
Creators: name: Nicole, Apelian
Publisher: name: Zenodo
Year: 2024

description: Unlock the key to optimal well-being with our insightful guide, "The Most Important Thing That's Probably Missing From Your Backyard." Dive into a realm beyond barbeque grills, pools, or vegetable gardens, and discover the crucial element that has the potential to significantly enhance the most vital aspect of your life – your health! This resource is a must-read for anyone seeking to transform their backyard into a haven of holistic wellness. Explore the pages and unlock the secrets to a healthier, more fulfilling lifestyle. Your backyard's transformation awaits!
Excavations at 19 High Street, Reigate
Creators: name: Clough, Helen
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 263-270
description: An archaeological excavation took place to the rear of 19 High Street, Reigate in advance of development. The excavation revealed evidence of settlement from the medieval and post-medieval periods. The medieval period was characterized by the presence of a possible pond and medieval foundations. The post-medieval period indicated further settlement in the form of floor and levelling surfaces and an eighteenth-century wall. The wall may have related to the brewery located on the site in the nineteenth century. Specialist reports include
Supplementary figure6c_vary_delta_no_cell_death_no_recovery_noname from A touch of sleep: biophysical model of contact-mediated dormancy of archaea by viruses
Creators: name: Gulbudak, Hayriye
name: Weitz, Joshua S.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: The canonical view of the interactions between viruses and their microbial hosts presumes that changes in host and virus fate require the initiation of infection of a host by a virus. Infection may lead to the death of the host cell and release of viruses, to the elimination of the viral genome through cellular defense mechanisms, or the integration of the viral genome with the host as a chromosomal or extra-chromosomal element. Here we revisit this canonical view, inspired by recent experimental findings in which the majority of target host cells can be induced into a dormant state when exposed to either active or de-activated viruses, even when viruses are present at low relative titer. We propose that both the qualitative phenomena and the quantitative time-scales of dormancy induction are consistent with the hypothesis that cellular physiology can be altered by contact on the surface of host cells rather than strictly by infection. In order to test this hypothesis, we develop and study a biophysical model of contact-mediated dynamics involving virus particles and target cells. We show how virus particles can catalyze cellular transformations amongst many cells, even if they ultimately infect only one (or none). We also find that population-scale dormancy is robust to variation in the representation of model dynamics, including cell growth, death, and recovery.
Strenghtening European Social Rights and Social Citizenship. EuSocialCit Policy Brief
Creators: name: Cantillon, Bea
name: Ferrera, Maurizio
name: Keune, Maarten
Publisher: name: Zenodo
Year: 2024

description: Based on the research of the EuSocialCit Horizon2020 project, in this policy brief we want to outline three sets of policy recommendations, aimed at strengthening the social rights of EU citizens. These sets of recommendations concern (1) social inclusion and minimum income protection; (2) better access to social rights; and (3) the strengthening of social governance.
Causal perception in Papio papio
Creators: name: Fagot Joel
name: Dautriche, Isabelle
name: Meewis, Floor
name: Claidière, Nicolas
Publisher: name: OSF Registries
Year: 2026
Subjects: subject: Evolution
subject: Life Sciences
subject: Ecology and Evolutionary Biology
subject: Cognition and Perception
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Comparative Psychology
subject: Causal perception
subject: Causality
subject: Primatology

description: In this study, we ask whether causal perception is present in a nonhuman primate: the Guinea baboon (Papio papio). We will attempt to train Guinea baboons to discriminate ‘Michottean’ causal from non-causal events. Furthermore, we will test whether it is easier to base such a discrimination on the abstract concept of causality compared to using low-level spatiotemporal properties. Also, we will test if the baboons are sensitive to event roles, known as agent and patient, which are present in causal, but not non-causal, events.
Electronic Supplementary Material from Reconstructing the emergence of a lethal infectious disease of wildlife supports a key role for spread through translocations by humans
Creators: name: Price, Stephen J.
name: Garner, Trenton W. J.
name: Cunningham, Andrew A.
name: Langton, Tom E. S.
name: Nichols, Richard A.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences

description: There have been few reconstructions of wildlife disease emergences, despite their extensive impact on biodiversity and human health. This is in large part attributable to the lack of structured and robust spatio-temporal datasets. We overcame logistical problems of obtaining suitable information by using data from a citizen science project and formulating spatio-temporal models of the spread of a wildlife pathogen (genus Ranavirus, infecting amphibians). We evaluated three main hypotheses for the rapid increase in disease reports in the UK: that outbreaks were being reported more frequently, that climate change had altered the interaction between hosts and a previously widespread pathogen, and that disease was emerging due to spatial spread of a novel pathogen. Our analysis characterized localized spread from nearby ponds, consistent with amphibian dispersal, but also revealed a highly significant trend for elevated rates of additional outbreaks in localities with higher human population density—pointing to human activities in also spreading the virus. Phylogenetic analyses of pathogen genomes support the inference of at least two independent introductions into the UK. Together these results point strongly to humans repeatedly translocating ranaviruses into the UK from other countries and between UK ponds, and therefore suggest potential control measures.
Electronic supplementary materials from An aquatic vertebrate can use amino acids from environmental water
Creators: name: Katayama, Noboru
name: Kobayashi Makoto
name: Kishida, Osamu
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: 60114 Systems Biology

description: Conventional food-web theory assumes that nutrients from dissolved organic matter are transferred to aquatic vertebrates via long nutrient pathways involving multiple eukaryotic species as intermediary nutrient transporters. Here, using larvae of the salamander Hynobius retardatus as a model system, we provide experimental evidence of a shortcut nutrient pathway by showing that H. retardatus larvae can use dissolved amino acids for their growth without eukaryotic mediation. First, to explore which amino acids can promote larval growth, we kept individual salamander larvae in one of eight different high-concentration amino acid solutions, or in control water from which all other eukaryotic organisms had been removed. We thus identified five amino acids (lysine, threonine, serine, phenylalanine and tyrosine) as having the potential to promote larval growth. Next, using 15N-labelled amino acid solutions, we demonstrated that nitrogen from dissolved amino acids was found in larval tissues. These results suggest that salamander larvae can take up dissolved amino acids from environmental water to use as an energy source or a growth-promoting factor. Thus, aquatic vertebrates as well as aquatic invertebrates may be able to use dissolved organic matter as a nutrient source.
Insights into the development of medieval and post-medieval riverside buildings at Mortlake
Creators: name: Darton, Lorraine
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 231-261
description: Archaeological excavations were recently undertaken on two riverside sites along the north side of Mortlake High Street, in an area where the sixteenth-century mathematician Dr John Dee once resided, and where Flemish weavers produced works for Charles I in the seventeenth century at the Mortlake tapestry works. A succession of late medieval and post-medieval buildings was discovered on plots between the river Thames and Mortlake High Street, in the London Borough of Richmond-upon-Thames. Two pits, a ditch and a structure, represented by stakeholes and postholes, pre-dated the late medieval buildings. The excavations revealed a complex sequence of floor surfaces and wall footings of houses, outbuildings and drains that once stood here. The earliest masonry structure may have been used as a fifteenth-century bakery or kitchen at the rear of a commercial property. Documentary research focusing on two seventeenth-century surveys has linked the changing ownership of properties with the development of the Mortlake tapestry works and the probable location of Dr John Dee's house. The changes in the architecture and plot layouts of the excavated buildings between the late medieval and post-medieval periods reflect urban building trends and show Mortlake increasingly becoming part of the City of London's trading hinterland. Specialist reports include
The Roman temple at Wanborough, excavation 1986-1986
Creators: name: O'Connell, M G
name: Bird, Joanna
Publisher: name: Archaeology Data Service
Year: 2002

description: Surrey Archaeological Collections, 82, 1-168
description: A coin hoard was deposited at the site in the period following the Claudian conquest of southern Britain. The first conclusive evidence of the religious nature of the site was in the form of a dedicatory deposit preceding the construction of a Romano-Celtic type temple in stone after the middle of the second century. The temple, together with at least one ancillary building, probably continued in use into the second half of the fourth century when demolition took place. The report begins with a `Preface and acknowledgement' by D G Bird (6-8), followed by the introduction, which includes brief mention of the setting and geology, catalogue of contexts (microfiche 2-4), and `Evidence for the later history of the site' by Shirley Corke (10 & 12). There follow details of the excavations, including earliest use of the site and pre-temple activity. The construction of the temple and ancillary buildings, its demolition and robbing out and later use of the site are also detailed, as is damage due to later treasure hunting. The finds section begins with `The coins' by C Cheesman (31-92) which includes appendices on `Possible Wanborough coins in the National Museum of Wales' (90), `Later Roman coins from the Wanborough site' (90-1) and `Results of the spectrographic analysis of selected coins' (92). Details of the excavated coins by phase are to be found in the microfiche (33-41). `Other finds excluding pottery' by Joanna Bird (93-132) has details of the copper alloy chain link headresses, three with wheel terminals that may indicate the Celtic Jupiter, the sceptres, and other religious objects including miniature axe pendants which may have been amulets, and ritual shears in copper alloy. These religious finds constitute the largest group of such to be found, and there is some discussion as to their significance. Specialist examination of all `Objects of copper alloy' (98-125) provides analyses of the material in its various guises, including the religious assemblage just mentioned along with earlier prehistoric palstave, spearhead, and sword hilts. Copper alloy brooches, rings, and miscellaneous objects are also listed. There is a `Report on the XRF analysis of six artefacts from Wanborough, Surrey' by M R Cowell (microfiche 42), a pear-shaped lead object, and objects of iron -- mostly nails. Metalworking debris and glass follow, the latter including beads and a small vessel. Clay loomweights, worked flint, and the quernstones complete the section. `The Roman pottery' by Joanna Bird (133-59) includes `Potters' stamps on samian ware' by Brenda Dickinson (137-8), and a catalogue of the Roman pottery. `The building material' by Joanna Bird (159-61) includes tiles with animal prints, and this is followed by `The animal remains' by Pat Nicolaysen (161-4) including shells. Finally there is a discussion and conclusions along with an extensive bibliography.
Investigation of Stane Street at South Holmwood, near Dorking
Creators: name: Hall, Alan
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 276-279
description: Brief report on a small exploratory excavation of Stane Street at Folly Farm, South Holmwood, in 2003, aimed at determining the nature of the remains of a known Roman road in farmland in preparation for a programme of tracing other possible roads within the county.
Investigation of a Bronze Age mound on Thursley Common
Creators: name: Graham, David
name: Graham, Audrey C
name: Wiltshire, Patricia E J
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 151-166
description: Following excavations in 1959, it was claimed that the two mounds close to the southern edge of the bog on Thursley Common, were not Bronze Age tumuli, as had previously been reported, but were in fact sand dunes. It was further suggested that most such mounds on the Surrey heathlands were of similar origin. Limited re-investigation of the western mound in 1995, however, revealed clear evidence of loose turf stack construction, for the presence of an external ditch and at least one possible primary burial. Palynological analysis of samples taken from the turves and buried soil levels indicate that the mound was likely to have been constructed in the Early/Middle Bronze Age. There is therefore no doubt that the mound is artificial and that it is almost certainly a barrow. It is highly likely therefore that the second mound, 180m to the east, is also of Bronze Age date and consequently that care should be taken before assuming that all such mounds are of natural origin. Specialist reports include
Recueil des édits, déclarations, lettres patentes, arrêts et règlements du roi registrés en la Cour du Parlement de Normandie, depuis l'année 1754 jusqu'en 1763, Rouen, Lallemand, 1774
Creators: name: N.R.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2017

description: Source: Bibliothèque universitaire du Tertiaire de Rouen, Faculté de droit.BB3274-9
description: Relation: vignette : https://www.nakala.fr/data/11280/feae92e8
Prehistoric, Roman and post-medieval settlement at Glyn House, Ewell
Creators: name: Stansbie, Daniel
name: Score, David
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 187-216
description: Excavations at Glyn House, Ewell, revealed prehistoric, Roman and post-medieval remains. Activity of Mesolithic date was identified by the presence of residual microliths. Two concentric curvilinear gullies (one of which contained a barbed-and-tanged flint arrowhead) and a tree-throw hole in the southeastern corner of the site indicated an area of Late Neolithic/Early Bronze Age activity. Lying to the northwest of the Late Neolithic/Early Bronze Age activity was evidence of Roman settlement, including a dense band of intercutting pits, part of a post-built structure and several deep pits (not fully excavated because of their depth), possibly well shafts. Overlying the Roman settlement was a post-medieval structure, which may have been the remains of the rectory, and a number of garden features. Specialist reports include
The Tramway at Chilworth Gunpowder Works
Creators: name: Crocker, Alan G
Publisher: name: Archaeology Data Service
Year: 2002

description: Surrey Archaeological Collections, 82, 181-195
description: A narrow-gauge tramway was installed in 1885 and ran until the works closed in 1920. It was extended several times in order to service new sections of the factory which were built for the manufacture of a different form of gunpowder and the modern propellant cordite. Information, deduced from documentary sources and physical remains, is presented on the layout of the tramway, the track, the bridges and the trams. A swingbridge, which carried a branch of the tramway across the millstream to the local railway station survives.
The Rowhook-Farley Heath branch road: excavations by I D Margary and A J Clark and further field observations
Creators: name: Hall, Alan
name: English, Judie
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 280-284
description: Discussion of papers by the late A J Clark relating to his work relating to the Romano-British road in the area of Coneyhurst Gill, and of further research by one of the authors.
A Late Bronze Age Site in Priory Park, Reigate
Creators: name: Williams, David W
Publisher: name: Archaeology Data Service
Year: 2002

description: Surrey Archaeological Collections, 82, 197-202
description: Following the discovery of a small group of bronze objects, including a socketed axe, on the summit of the ridge in Priory Park, a limited excavation recovered a small group of LBA pottery. The finds suggest a settlement. There were no accompanying archaeological features. There are reports on `The pottery' by Steve Dyer (200-1) and thirty pieces of `Flintwork' by Roger Ellaby (201) including two arrowheads.
Supplementary methods, figures and tables from Male courtship decisions are influenced by light environment and female receptivity
Creators: name: Cole, Gemma L.
name: Endler, John A.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: The appearance of animal colour signals depends jointly upon the ambient light spectrum and the signal's reflectance spectra. Light environment heterogeneity might, therefore, allow individuals to enhance their signal by signalling in an environment that increases signal efficacy. We tested this hypothesis by providing male guppies (Poecilia reticulata), a choice of three light environments in which to display their colour signal to females: green, lilac and clear. We paired males with both receptive and non-receptive females to test whether female response might affect male behavioural decisions. Males preferred the clear environment in all trials and this environment also resulted in males having the highest average visual contrast. Sexual behaviour was influenced by complex interactions between female receptivity, light environment and male colour pattern contrast. Males spent significantly more time in the environment in which their colour signal had the highest contrast, but only when paired with receptive females. Significant interactions between light environment and individual male colour components were also seen only in receptive trials. Our results suggest that males use light environment to enhance their colour pattern, but only in the presence of receptive females.
The Surrey Archaeological Society from 1954 to 2004
Creators: name: Christophers, Richard
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 285-306
description: Brief account of the Society's third half-century. Themes discussed include the need for space for its collections, and the search for a permanent headquarters; and the change from a largely amateur, antiquarians' society to one which, while continuing to find a role for the amateur, has taken on a professional role and provided an impetus for action by statutory and elected bodies, particularly in the areas of excavation and conservation. Includes
The archaeology of industrial extraction from Banstead and Walton Heaths
Creators: name: Bagnall, Colin
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 167-186
description: The article gives an account of the history or possible history of the fifty pits shown on the Ordnance Survey maps of Banstead and Walton Heaths surveyed between 1866 and 1934. Much of this history is associated with the extraction from 1755 onwards of flints and gravel for the building and maintenance of the two turnpike roads which crossed the heath, the Brighton and Pebble Hill Roads (the later A217 and B2032). Details are given of the Reigate Turnpike Trust's construction of the roads, the likely sources of the materials in terms of pits, the relevance of payments for carting in the identification of those pits and the use of the pits in the improvements made by the road engineer William Constable. The account goes on to deal with extraction by the Trust's successors, the Epsom District Highways Board and the Epsom Rural District Council. Identification of the pits likely to have been opened by these bodies is attempted, with information derived from their records and those of the Banstead Commons Conservators. Manorial and other extractors, and the extraction of chalk and loam, are also considered.
Archaeology in Surrey 1991
Creators: name: Bird, David G
name: Crocker, Glenys M
name: McCracken, J S
name: Saich D, Dinah
Publisher: name: Archaeology Data Service
Year: 2002

description: Surrey Archaeological Collections, 82, 203-219
description: Pr�cis of work during the year, both in the administrative county and the south-west London boroughs.
Supplementary Material from Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I
Creators: name: Bogomolovas, Julius
name: Fleming, Jennifer
name: Anderson, Brian R.
name: Williams, Rhys
name: Lange, Stephan
name: Simon, Bernd
name: Muzamil M. Khan
name: Rudolf, Rüdiger
name: Franke, Barbara
name: Bullard, Belinda
name: Rigden, Daniel J.
name: Granzier, Henk
name: Labeit, Siegfried
name: Mayans, Olga
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Structural Biology

description: Missense single-nucleotide polymorphisms (mSNP) in titin are emerging as a main causative factor of heart failure. However, distinguishing between benign and disease-causing mSNPs is a substantial challenge. Here, we research the question of whether a single mSNP in a generic domain of titin can affect heart function as a whole and, if so, how. For this, we studied the mSNP, T2850I, seemingly linked to arrhythmogenic right ventricular cardiomyopathy (ARVC). We used structural biology, computational simulations and transgenic muscle in vivo methods to track the effect of the mutation from the molecular to the organismal level. The data show that the T2850I exchange is compatible with the domain three-dimensional fold, but that it strongly destabilizes it. Further, it induces a change in the conformational dynamics of the titin chain that alters its reactivity, causing the formation of aberrant interactions in the sarcomere. Echocardiography of knock-in mice indicated a mild diastolic dysfunction arising from increased myocardial stiffness. In conclusion, our data provide evidence that single mSNPs in titin's I-band can alter overall muscle behaviour. Our suggested mechanisms of disease are the development of non-native sarcomeric interactions and titin instability leading to a reduced I-band compliance. However, understanding the T2850I-induced ARVC pathology mechanistically remains a complex problem and will require a deeper understanding of the sarcomeric context of the titin region affected.
A Survey of the Earthworks at St Ann's Hill, Chertsey
Creators: name: McOmish, David Scott
name: Field, David J
Publisher: name: Archaeology Data Service
Year: 2002

description: Surrey Archaeological Collections, 82, 223-224
description: Reports analytical ground survey by RCHME. A univallate hillfort earthwork with remaining traces of a second, outer, rampart can be seen. The best preservation occurs to the west where the rampart stands to 1m high, fronted by a ditch. The north and east sides are more difficult to define, and a number of terraces appear to be in evidence. Several paths interrupt the line of the defences including the fourteenth-century `King's way from Chertsey to the chapel of St Ann' and the London to Winchester coach road, as well as the modern variety. The hillfort remains undated, although multi-period chance finds indicate frequent if not continuous use over several periods.
To change the law: the story behind the Treasure Act 1996
Creators: name: Graham, David
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 307-314
description: On the involvement of members of the Surrey Archaeological Society in the campaign leading to the replacement of the ancient law of Treasure Trove by the Treasure Act 1996, and the Society's experiences at the treasure trove site at Wanborough, near Guildford, which led to their involvement.
Supplementary Materials from Molecular stripping, targets and decoys as modulators of oscillations in the NF–κB/IκBα/DNA genetic network
Creators: name: Zhipeng Wang
name: Potoyan, Davit A.
name: Wolynes, Peter G.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: 60114 Systems Biology
subject: FOS: Biological sciences
subject: 60113 Synthetic Biology

description: Eukaryotic transcription factors in the NF–κB family are central components of an extensive genetic network which activates cellular responses to inflammation and to a host of other external stressors. This network consists of feedback loops that involve the inhibitor IκBα, numerous downstream functional targets and still more numerous binding sites that do not appear to be directly functional. Under steady stimulation the regulatory network of NF–κB becomes oscillatory and temporal patterns of NF–κB pulses appear to govern the patterns of downstream gene expression needed for immune response. Understanding how the information from external stress passes to oscillatory signals and is then ultimately relayed to gene expression is a general issue in systems biology. Recently in vitro kinetic experiments as well as molecular simulations suggest that active stripping of NF–κB by IκBα from its binding sites can modify the traditional systems biology view of NF–κB/IκBα gene circuits. In this work we revise the commonly adopted minimal model of the NF–κB regulatory network to account for the presence of the large number of binding sites for NF–κB along with dissociation from these sites which may proceed either by passive unbinding or by active molecular stripping. We identify regimes where the kinetics of target and decoy unbinding and molecular stripping enter a dynamic tug of war which may either compensate each other or amplify nuclear NF–κB activity, leading to distinct oscillatory patterns. Our finding that decoys and stripping play a key role in shaping the NF–κB oscillations suggests strategies to control NF–κB responses by introducing artificial decoys therapeutically.
Supplementary material from Auditory mechanics in a bush-cricket: direct evidence of dual sound inputs in the pressure difference receiver
Creators: name: Thorin Jonsson
name: Montealegre-Z, Fernando
name: Soulsbury, Carl
name: Brown, Kate A. Robson
name: Robert, Daniel
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Biophysics
subject: 110601 Biomechanics
subject: FOS: Health sciences

description: The ear of the bush-cricket, Copiphora gorgonensis, consists of a system of paired eardrums (tympana) on each foreleg. In these insects, the ear is backed by an air-filled tube, the acoustic trachea (AT), which transfers sound from the prothoracic acoustic spiracle to the internal side of the eardrums. Both surfaces of the eardrums of this auditory system are exposed to sound, making it a directionally sensitive pressure difference receiver. A key feature of the AT is its capacity to reduce the velocity of sound propagation and alter the acoustic driving forces at the tympanum. The mechanism responsible for reduction in sound velocity in the AT remains elusive, yet it is deemed to depend on adiabatic or isothermal conditions. To investigate the biophysics of such multiple input ears, we used micro-scanning laser doppler vibrometry and micro-computed X-ray tomography. We measured the velocity of sound propagation in the AT, the transmission gains across auditory frequencies and the time-resolved mechanical dynamics of the tympanal membranes in Copiphora gorgonensis. Tracheal sound transmission generates a gain of approximately 15 dB SPL, and a propagation velocity of ca 255 m s−1, an approximately 25% reduction from free field propagation. Modelling tracheal acoustic behaviour that accounts for thermal and viscous effects, we conclude that reduction in sound velocity within the AT can be explained, among others, by heat exchange between the sound wave and the tracheal walls.
Two centuries of rubbish: excavations at an 18th and 19th century site at 12-18 Albert Embankment, Lambeth
Creators: name: Tyler, Kieron
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 105-136
description: The article outlines the results of two phases of excavation at 12--18 Albert Embankment, Lambeth. The site was partially excavated in 1988; however, areas around the edge and north of the site were not examined and excavation of the remainder of the site was undertaken in 2000. The excavations demonstrated the rapid and relentless pattern of change that took place in Thameside Lambeth from the mid-eighteenth to the mid-nineteenth centuries. An area of market gardens and semi-rural settlement became a densely occupied urban slum. The archaeological sequence and the associated finds showed how these changes had actually occurred. Period 1 represented the geological horizon; subsequently the site was cultivated (period 2). This activity ceased c. 1745 and in period 3 the site became built up. Associated with the construction of Buildings 1 and 2 was Open Area 3 that contained a substantial dump of pothouse waste. Dated to 1745--70, this assemblage included tin-glazed ware, stoneware and London area post-medieval redware. Both kiln furniture and vessels (including wasters) were found. The kiln furniture included forms used for both tin-glazed and redwares, suggesting that both wares may have been manufactured at the same pothouse. Furthermore, the assemblage included the first examples of eighteenth-century redware kiln furniture. It is suggested that this assemblage derived from either the pothouse at Norfolk House or that at Vauxhall, the only local pothouses known to be making both stoneware and tin-glazed ware between 1745 and 1770. The excavation suggests that London area post-medieval redwares may also have been manufactured at either of these Lambeth pothouses. This is the first evidence for the manufacture of eighteenth-century redwares in Lambeth. From the early nineteenth century the use of the site intensified (period 4): sixteen cesspits were recorded. In period 5 these cesspits were backfilled as one event, during the period 1851--60, as a result of the arrival of piped sewage disposal in the area. The large backfill assemblages are discussed, giving an insight into the status and lifestyle of mid-Victorian Lambeth's residents. Specialist reports include
A Native North American Projectile Point from Cranleigh
Creators: name: Nicolaysen, Pat
Publisher: name: Archaeology Data Service
Year: 2002

description: Surrey Archaeological Collections, 82, 227-228
description: Reports a greyish-brown chert projectile point with asymmetrical sides which may indicate it is a native N American item dating from cAD200. The circumstances of its deposition are unknown and it may also be a modern replica.
Welcome to Pontibus - gateway to the west
Creators: name: McKinley, Jacqueline I
Publisher: name: Archaeology Data Service
Year: 2005

description: Surrey Archaeological Collections, 91, 1-69
description: A five-year programme of archaeological investigations was undertaken within a c.9ha area to the north of the High Street, Staines on land formerly predominantly occupied by the Central Trading Estate. The vast majority of the archaeological evidence pertains to the Romano-British settlement established in the second half of the first century AD at this bridging point across the Thames, forming the main route from London to the west of the province. The early settlement flourished, with expansion in the second century AD, followed by a hiatus and apparent contraction in the late-second/early-third centuries, occupation continuing to the end of the Roman period. Much of the land to the north of the main road formed areas of refuse disposal and small-holdings, with probable animal corralling and grazing, the latter extending into the rich meadowland bordering the north side of the gravel island on which the town was built. The single building for which evidence was recovered corresponds with the second-century phase of expansion. The basic economy of the town seems to have remained much the same throughout the Romano-British period, with most foodstuffs being brought in from the surrounding area. Post-Roman activity was negligible until the twelfth century, with a subsequent concentration in the eastern half of the main gravel island. Here, burgage plots -- small-holdings, some used for horticultural purposes, others for storage/stabling and the keeping of animals -- extending on to the water-meadows to the north, were established at right-angles to the course followed by the current High Street.