cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Characterising the ferret as an experimental model of bovine tuberculosis
Creators: name: Lauterkorn, Niranjani
Publisher: name: University of Surrey
Year: 2024
Subjects: Bovine tuberculosis
Cytokine kinetic post TB infection
Humoral response to TB ferret
Ferret as a model of TB
Transmission of TB within ferret population
Severity of TB ferrets

description: Mycobacterium bovis (M. bovis) causes bovine tuberculosis (bTB), a biosafety and economic concern to farmers and the public. The UK has the most bTB cases in Europe, followed by Ireland and Spain. The eradication of bTB is regulated by the World Health Organisation for Animal Health (OIE), which promotes the necessity of long-term management of transmission from infected wildlife to livestock, including European badgers (Meles meles). This is essential despite the implementation of expensive testing and slaughter policies over the course of several decades. To explore host-response interactions and establish infection markers for badgers, ferrets (Mustela furo) were utilised as "clean," cost-effective laboratory-adapted mustelid surrogates. Two studies were conducted to investigate the immunopathogenesis caused by M. bovis in ferrets subjected to intratracheal (IT) inoculation or direct contact for a period of ten months. Most experimentally infected ferrets developed macroscopically and microscopically identical TB-like granulomas to those of TB-infected badgers. Differences in IFN-γ, TNF-α, IL-2, and IL-17A levels and kinetics were seen in fresh and cryopreserved peripheral mononuclear cells (PBMCs) stimulated with M. bovis antigens, PPD-B, ESAT-6, and CFP-10 post-infection. Like badgers, infected ferret PBMCs produced IFN-γ and responded similarly to PPD-B and CFP-10. The two species' IgG reactions to MPB83 were likewise comparable. Both studies revealed that IgG responses to MPB83, TNF-α, IL-17A, and IFN-γ (fresh PBMCs) responses to PPD-B correlated with total granuloma scores, while IL-2 and CXCL10 did not. Intriguingly, the in-contact ferret population showed low IFN-γ responses throughout the study. High plasma IL-17 levels, robust IgG responses to MPB83, and high IL-2 and TNF-α responses to PPD-B, ESAT-6, and CFP-10 indicate exposure to M. bovis. These responses may improve M. bovis infection detection in the field. Biomarkers for M. bovis exposure are of great benefit as they facilitate the analysis of response variability in vaccination efficacy trials.
Strategic change in the tourism experience ecosystem
Creators: name: Cloarec, David Yohann
Publisher: name: University of Surrey
Year: 2024

description: This thesis presents a comprehensive investigation into enhancing tourism experiences through strategic changes in management and marketing practices. The research adopts an interdisciplinary approach, integrating social and environmental psychology with organisational theories to comprehend the intricate dynamics of the tourism industry and its customer-centric transformation. The first part focuses on the role of servant leadership in tourism organisations, emphasising its alignment with service and innovation climates for strategic service differentiation. It highlights the importance of clear strategic objectives and a co-creation culture to facilitate value co-creation with stakeholders. The findings demonstrate how servant leadership fosters collaboration, innovation, and customer-centricity, making it a crucial strategic change for enhancing customer value. This knowledge directly informs the second part, investigating how experiential marketing practices can align with the customer-centric vision. This research continues by exploring the impact of media formats and narrative structures on customer attitudes and intentions on social media, using psychophysiological lab experiments. It reveals that destinations and tourism organisations can use different strategies to achieve different goals. The findings demonstrate that videos are more effective to convey information for new audiences while photos and audio can be appropriate for existing customers. The study reveals that first-person and third-person narrators influence emotional responses and consumer preferences differently, with first-person narratives enhancing trust and third-person narratives conveying emotions. Overall, this thesis contributes significantly to the field of tourism research, providing practical guidance for managers and marketers. The innovative use of psychophysiological lab experiments enhances understanding of consumer behaviour, laying the foundation for future research in this dynamic and evolving industry.
Ein Strich durch die Rechnung: Eine Verordnung soll die Pharmabranche in Indonesien zügeln
Creators: name: Bastian, Saskia
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Durch den Bevölkerungsreichtum überrascht es nicht, dass die Pharmabranche in Indonesien als Wachstumsmarkt gehandelt wird.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
A novel design and optimization of a polymeric aortic valve using numerical and experimental techniques
Creators: name: Hassanzadeh Gharaie, Saleh
Publisher: name: Swinburne
Year: 2024

description: In this Ph.D. research, an accurate numerical method to predict the kinematics of the heart valve leaflets has been developed. The numerical scheme was used to optimize the proposed design of a prosthetic heart valve. The optimization process aimed at addressing the aggressive fatigue failure issue associated with current valve designs. A prototype of the optimized valve was constructed using advanced manufacturing techniques including electron beam melting and 3D printing methods, which is the first time that such techniques have been combined to construct a prosthetic valve. The performance of the optimised valve was evaluated thoroughly with respect to both structural and haemodynamic performance. The improvements of haemodynamic performance of the valve achieved in the present study can reduce left ventricle hypertrophy which improves long-term survival of patients receiving prosthetic heart valve.
Diversifying with dignity: An explorative study of work transitions from fishing to tourism in Cornwall, UK
Creators: name: WINCHENBACH, ANKE
Publisher: name: University of Surrey
Year: 2022

description: Reduced fishing opportunities globally and in the UK have resulted in the income of many fishermen becoming insufficient. The growing area of marine tourism is widely considered as a possible diversification strategy. However, previous work has largely focused on these issues from a quantitative perspective, and scant attention has been paid to understand the experiences of those affected by such changes. This PhD thesis addresses this gap by exploring the ways in which people working in fishing and marine tourism in Cornwall understand, experience, and attach meaning to their work through the theoretical lens of identity and dignity. From a social constructionist perspective and supported by principles of a phenomenological enquiry, empirically, this paper draws on interviews with 15 commercial fishermen, 7 fishermen who transitioned into tourism work, as well as 23 informants including descendants and relatives of fishermen and community members, artists and local filmmakers, as well as representatives of fishing and tourism and heritage organisations. Throughout the corpus of data, perceptions of self and identity were nuanced, complex, and sometimes even contradictory. Findings show the ways in which psychological, physical, relational, and wider socio-economic and policy dimensions play a role in how people experience and attach meaning to their work. Findings indicate that while fishermen largely perceive their work as meaningful, for some participants fishing is no longer ‘a way of life’. This study highlights challenges for dignified work in fishing due to increased commercial pressure and policy constraints. With respect to diversified fishermen, the empirical evidence suggests that participants remained deeply rooted in their fishing identities, while trying to navigate, justify and make sense of their new role. This study shows that livelihood transitions can create opportunities for restoring economic dignity, and to improve physical and mental health. Accordingly, there is a need to consider workplace dignity in discussions on fishing livelihoods, and for closer collaboration between fisheries and tourism workers, managers, funders, and policymakers to effectively guide and facilitate work transitions. Finally, this thesis offers an alternative understanding of identity and dignity in marine tourism contexts and highlights the relevance of dignity as a concept for theorising tourism diversification.
Helicoconis (Fontenellea) hispanica Ohm 1965
Creators: name: Tillier, Pierre
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Coniopterygidae
Helicoconis
Helicoconis hispanica

description: Helicoconis (Fontenellea) hispanica Ohm, 1965
Helicoconis hispanica Ohm, 1965: 196.
CATÉGORIE ZOOGÉOGRAPHIQUE. — Espèce atlanto-méditerranéenne.
MATÉRIEL EXAMINÉ. — M10-CAÏ2000 T 2-M2 (1 ♂).
DISTRIBUTION DANS LE MERCANTOUR. — Saorge (Tillier 2013c)
REMARQUE
Espèce connue du Maroc, d’Espagne, de Sicile et de Sardaigne (Aspöck et al. 2001). La capture d’un mâle sur la commune de Saorge constitue la première mention de cette espèce en France (Tillier 2013c).
description: Published as part of Tillier, Pierre, 2015, Raphidioptera et Neuroptera (Insecta, Neuropterida) du Parc national du Mercantour (France), pp. 581-594 in Zoosystema 37 (4) on page 590, DOI: 10.5252/z2015n4a4, http://zenodo.org/record/5156903
Family Accommodation to Eating Disorder Behaviours in Young People and Associations with Parents’ Distress Intolerance
Creators: name: ZINSER, JENNIFER LOUISE
Publisher: name: University of Surrey
Year: 2022

description: Background and Aim. Family accommodation has been identified as a maintaining factor of eating disorders, with families often caught up in the rigid behaviours that characterise the illness. Given that parents often accommodate symptoms of their child’s eating disorder to reduce family conflict and the young person’s distress, levels of parents’ distress tolerance may help explain the variability seen in family accommodation. This study aimed to investigate the relationship between parental distress tolerance (specifically tolerance of negative emotions and intolerance of uncertainty) and family accommodation and assess the role of illness severity, caregiver burden, and parents’ mental health on this association.

description:

description: Methods. Parents or carers (N=84) of young people (aged <18) with a suspected or diagnosed eating disorder completed an online survey comprising of screening questions, demographic and clinical information, validated questionnaires, and questions about the impact of the COVID-19 pandemic.

description:

description: Results. Tolerance of negative emotions (TNE), but not intolerance of uncertainty, was significantly associated with family accommodation. Multiple regression analyses revealed that when other significant correlates of accommodating behaviour were entered into the model (caregiver mental health and caregiver burden), only caregiver burden remained significantly associated with family accommodation. Bootstrapped mediation analysis indicated that the association between TNE on family accommodation is fully mediated by caregiver burden.

description:

description: Conclusions. There is an association between parents’ tolerance of negative emotions and accommodation behaviours, however this association was fully mediated by caregiver burden. The clinical implications and directions for future research to consider are discussed.
Parasemidalis fuscipennis
Creators: name: Tillier, Pierre
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Coniopterygidae
Parasemidalis
Parasemidalis fuscipennis

description: Parasemidalis fuscipennis (Reuter, 1894)
Coniopteryx fuscipennis Reuter, 1894: 32.
Parasemidalis annae Enderlein, 1905: 198.
CATÉGORIE ZOOGÉOGRAPHIQUE. — Espèce holarctique.
MATÉRIEL EXAMINÉ. — M10-CAÏ2000 T2 -M1 (1 ♀); M10-CAÏ2000 T2 -IN (1 ♀); M11- LAR1500 T2 -M1 (1 ♀).
DISTRIBUTION DANS LE MERCANTOUR. — Saorge, Meyronnes.
REMARQUE
Espèce nouvelle pour le Mercantour.
description: Published as part of Tillier, Pierre, 2015, Raphidioptera et Neuroptera (Insecta, Neuropterida) du Parc national du Mercantour (France), pp. 581-594 in Zoosystema 37 (4) on page 590, DOI: 10.5252/z2015n4a4, http://zenodo.org/record/5156903
Rauchwolken über Indonesien: Staatlicher Raucherschutz bleibt aus
Creators: name: Stratil, Michael P.
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Im November explodierte der Vulkan Merapi und setzte gewaltige Mengen an heißer Asche, Rauch und giftigen Gasen frei und Tötete während seiner anhaltenden Aktivitäten bislang 325 Menschen. Der größte indonesische Zigarettenproduzent Sampoerna reagierte prompt und entsandte ein Katastrophen-Rettungsteam.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Sounds of nature : what influences judgments of nature-based and non-nature-sounds?
Creators: name: Barton, Rebecca
Publisher: name: University of Surrey
Year: 2020

description: Objectives: This study aims to replicate previous findings that nature-sounds are preferred over non-nature-sounds. It also aims to explore possible links between any feelings or thoughts that sounds evoke in individuals and how they then rate those sounds, and how these might link to current theories of stress reduction and attention restoration. Method: Using a questionnaire design, 104 participants listened to three nature-based and three non-nature-sounds. They were then asked to rate the sounds and invited to describe thoughts and feelings that came to mind whilst listening to the sounds. These written responses were then examined and coded resulting in nine variables being created, such as mentioning a memory, writing in the first person, mentioning nature and positivity of written comment. Mean sound ratings were then compared between responses that did and did not match the variables. Results: Nature-sounds received higher sound ratings than non-nature-sounds and they generated more positive comments. The presence of the above variables also resulted in higher sound ratings overall for the nature-sounds than the non-nature sounds, with the use of positive emotive words, mentioning a memory and mentioning nature having the biggest effects. Conclusion: The results suggest some support for both stress reduction and attention restoration, as well as highlighting a possible role for positive affect and memories that seems to be linked more with nature than non-nature-sounds. This may support the use of nature and nature-sounds in individualised therapeutic interventions that may generate positive emotions, process negative ones, broaden mindsets and, facilitate stress reduction and attention restoration.
Heterotic vacua and their universal geometry.
Creators: name: Sisca, Roberto
Publisher: name: University of Surrey
Year: 2020

description: We consider perturbative heterotic string backgrounds. These are described by an SU(3) structure with torsion, a holomorphic stable vector bundle with a connection A that solves Hermitian-Yang-Mills equation and a three-form H that satisfies an anomaly cancellation condition. Firstly, we are interested in how the string scale affects the infinitesimal moduli problem. This involves studying deformations of background fields that preserve the equations of motion, the action of the symmetry group on them, a convenient choice of gauge-fixing. We determine the Hodge decompositions of the fields deformations perturbatively. Secondly, we consider a perspective in which these backgrounds are fibered over their parameter space. This is the universal geometry of the title. Symmetry transformations are allowed to depend on parameters and the process of defining deformations involves derivatives that are appropriately covariantised. In this formalism all the fields as well as some of the equations have a natural extension to a ‘universal bundle’.
Physicochemical Characterisation of Graphene Based 2D Materials for Industrial Applications
Creators: name: LEGGE, ELIZABETH JEAN
Publisher: name: University of Surrey
Year: 2021

description: "Graphene has had significant attention since it was successfully isolated in 2004 by Geim and Novosolov, who were later awarded the Nobel Prize in Physics for their outstanding work. The discovery uncovered a whole new area of research into 2D materials with numerous applications. 16 years later, graphene is now transitioning into industry. However, for the transition to be successful, the supply chain needs internationally agreed measurement standards in place and methods for comparing different types of graphene.
description: There are many variations of what is commonly referred to as “graphene”, with differences in size, chemistry and bulk form. This thesis includes the structural characterisation of graphene, describing the research on which the NPL Good Practice Guide (No. 145) was based. This GPG will form the basis of two international ISO standards, one for flakes (ISO TS 21356-1), and another for CVD-grown sheets (ISO NWI 21356-2). ISO standards are important in industry for maintaining consistency across different institutions and companies, and ensuring repeatable and reliable measurements.
description: The chemical characterisation of graphene requires a more thorough investigation, and additional measurement techniques. This thesis explores the physicochemical characterisation of three different types of material (graphene oxide, a graphitic powder containing few-layer graphene flakes, and graphene sheets), and the suitability of their modified forms (reduced graphene oxide, functionalised flakes, and functionalised sheets) for use in several applications (conductive thin films, nanocomposites, and biosensors).
description: The work in this thesis has improved our understanding of functionalised graphene and in turn aided in its optimisation for industrial products. Graphene oxide (GO) has been significantly reduced at low temperatures (150°C), resulting in competitive sheet resistances (~1.3 kΩ□-1). For the first time, tip-enhanced Raman spectroscopy (TERS) measurements have been performed on a commercially available product containing few-layer graphene and show differences between the location of functionalisation (edge vs basal plane), and the effect on the final nanocomposite. Finally, functionalised sheets of graphene have been investigated for their use as biosensors, by combining Raman spectroscopy and atomic force microscopy measurements, enhancing our understanding of the bonding mechanisms and observing changes that have not been recorded previously for single layer graphene sheets in atmospheric conditions."
In die Zange genommen: Überlegungen zur islamischen Kulturindustrie in Indonesien
Creators: name: Duile, Timo
name: Kleißle, Christian
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: In diesem Artikel soll für Indonesien untersucht werden, was die Kritische Theorie in der Tradition Adornos und Horkheimers als Kulturindustrie bezeichnet. Obwohl viele Problematiken, auf welche die Kritische Theorie verwiesen hat, in Asien in besonders großem Maße zu beobachten sind, wurde diese Thematik noch kaum untersucht.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Distoleon tetragrammicus
Creators: name: Tillier, Pierre
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Myrmeleontidae
Distoleon
Distoleon tetragrammicus

description: [Distoleon tetragrammicus (Fabricius, 1798)]
Myrmeleon tetragrammicus Fabricius, 1798: 205.
CATÉGORIE ZOOGÉOGRAPHIQUE. — Espèce holoméditerranéenne expansive.
DISTRIBUTION DANS LE MERCANTOUR. — [Barcelonnette] (Leraut 1992c).
description: Published as part of Tillier, Pierre, 2015, Raphidioptera et Neuroptera (Insecta, Neuropterida) du Parc national du Mercantour (France), pp. 581-594 in Zoosystema 37 (4) on page 591, DOI: 10.5252/z2015n4a4, http://zenodo.org/record/5156903
Die Generäle und ihr Geld: Ein kurzer Blick in die verborgenen Finanzierungsstrukturen des indonesischen Offizierkorps
Creators: name: Wandelt, Ingo
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Volle finanzielle Transparenz war eine Hauptforderung an die militärische reformasi der indonesischen Streitkräfte (INI) nach dem Ende des Suharto-Regimes. Einiges ist in diese Richtung vorangebracht worden.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
The Macroeconomics of Foreign Exchange Intervention in an Emerging Economy
Creators: name: De Freitas Rocha Cambara, Leilane
Publisher: name: University of Surrey
Year: 2024

description: This thesis contains three interconnected chapters that explore foreign exchange intervention
description: policy.

description:

description: Chapter 1 motivates the topic, highlighting the importance of this type of policy, which
description: can be compatible with inflation targeting, as an additional instrument to monetary
description: policy. The chapter also presents a first estimation of Taylor-type foreign exchange
description: intervention rules using Brazilian data. Brazil adopted an inflation-targeting regime
description: with floating exchange rates in 1999 and has been using FX intervention since then.
description: The results suggest that the Central Bank of Brazil leans against the wind following a
description: depreciation of the domestic currency.

description:

description: Chapter 2, then, expands the analysis with a microfounded model and the Bayesian
description: estimation of both interest rate and foreign exchange intervention rules. It provides
description: more evidence that the Brazilian monetary authority, in addition to having an inflationtargeting
description: behaviour, also leans against the wind in response to currency depreciation.
description: The results also suggest that this happens in response to any shock that causes a
description: depreciation, not only to foreign shocks.

description:

description: Finally, Chapter 3 uses the model estimated in Chapter 2 to jointly optimise a simple
description: monetary policy rule and a simple foreign exchange intervention rule, which is the main
description: contribution of this thesis. The results show that the introduction of the intervention
description: policy is welfare-improving when compared to the case in which only monetary policy
description: is available to the central bank. The adoption of simple mandates that penalise the
description: variance of inflation, output, and depreciation has welfare costs that depend on the
description: mandate’s design.
Mit oder ohne Verantwortung? Großkonzerne oder: Wer regiert Indonesien?
Creators: name: Suroso, Jusuf
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2019

description: In der Ausgabe der The Straits Times (Singapore) vom 20. August 2010 drückte Robin Chan die Stimmung der internationalen Großkonzerne bezüglich Indonesien wie folgt aus: »S'pore Investors Pour Money Into Indonesia«. Im zweiten Quartal dieses Jahres investierte Singapur 1,6 Milliarden US-Dollar in Indonesien, obwohl Indonesien als ein korruptes Land mit schwacher Infrastruktur und aufgrund vieler politischer Unruhen als geschwächt gilt.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Nachrichten
Creators: name: Stratil, Michael P.
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Nachrichten aus der Region.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Singapore Inc.: Macht und Einfluss der Government Linked Companies (GLC)
Creators: name: Willer, Ragnar K.
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Die singapurische Regierung greift immer wieder regelnd und gestaltend in die Wirtschaft ein, um sie voranzubringen. So schafft sie die Rahmenbedingungen und übt darüber hinaus einen unternehmerischen Einfluss aus, der von den mit der Regierung verbundene Unternehmen ausgeht.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Challenging Capacity: Effective Participation and Vulnerability in Clinical Negligence Litigation
Creators: name: PETERS, KATY
Publisher: name: University of Surrey
Year: 2022

description: This thesis describes an intellectual journey, undertaken in response to concerns about the limitations of litigation capacity, which confronts the challenge of applying a vulnerability approach to both humans and human-created systems.
description:

description: The thesis argues that litigation vulnerability in clinical negligence claims should be conceptualised by reference to dependencies and differences which influence barriers to effective participation in the litigation process. It seeks to provide a framework for recognising vulnerability in the context of clinical negligence litigation, then proposes legislative tools and scrutiny measures which may facilitate litigation resilience. It posits that measures enabling access to justice require mechanisms for continuous scrutiny to ensure effective accessing of justice.

description:

description: The thesis proposes that litigation vulnerability should be determined by reference to the overriding objective of the Civil Procedure Rules rather than predefined human characteristics. In reaching this conclusion, the thesis draws on critical legal theories, in particular the work of Martha Fineman, to examine vulnerability in relation to both the human participants and human-created frameworks.

description:

description: The thesis identifies barriers to effective participation in litigation as a key determinant of litigation vulnerability. It posits that barriers to effective participation arise where participation is compromised or controlled as a result of human or systemic vulnerability. It argues that litigation support should be predicated on enabling a collaborative approach of effective participation by all participants whose voices will be relevant to the Civil Procedure Rules’ overriding objective.
Supersymmetry of de-Sitter Solutions in String Theory
Creators: name: Di Gioia, Mirco
Publisher: name: University of Surrey
Year: 2023

description: In the first part of the Thesis, we investigate some background material which is utilized in the second part, where the original research is presented. We present the proof of how the supercovariant derivative acting on a spinor is Spin-gauge covariant. We introduce the spinorial geometry techniques used to analyze the Killing spinor equations (KSEs), and give an example in the case of the gaugino KSE of certain warped product solutions of D = 10 heterotic supergravity. We describe the isometries of de Sitter space and we give the ansatz for warped product dS4 solutions. Then, we briefly prove some classical no-go theorems for warped product de Sitter solutions.

description:

description: In the second part of the Thesis, the necessary and sufficient conditions for warped product dS4 solutions in D =11 supergravity to preserve the minimal N = 8 supersymmetry are determined. We find, on integrating the KSE along the dS4 directions, that the necessary and sufficient conditions for supersymmetry are encoded in a single gravitino-type equation, which is satisfied by a spinor ψ whose components depend only on the co-ordinates of the internal space. The spinor ψ is associated with two possible stabilizer groups, SU(3) or G2. We derive explicitly the Spin(7) gauge transformations which are used to write ψ in simple canonical forms with stabilizer subgroups SU(3) or G2. We then solve the linear system obtained from the KSEs. In particular, we show that the linear system implies there are no solutions for which the stabilizer of ψ is G2. For the case of SU(3) stabilizer subgroup, the KSEs determine all components of the 4-form flux in terms of the geometry of the internal manifold, and we present the geometric conditions and the components of the flux, written in a SU(3) covariant fashion.
Nachrichten
Creators: name: Wieczorek, Nina
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Nachrichten aus der Region.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Appraising the difficulty of permutation problems using local search and prediction
Creators: name: Gheorghita, Marius Oliver
Publisher: name: Swinburne
Year: 2024

description: The research has been conducted in the field of optimisation algorithms with a focus on techniques which find approximate good solutions and use the information from the search to learn about the complexity of the problems. Optimisation algorithms can be applied to find solutions to real-world complex problems and learning about the difficulty of problems is especially useful when tacking unknown problems. The research is applicable to combinatorial problems and many real problems can be modelled as combinatorial problems, e.g. assignment, routing, scheduling problems.
Libelloides coccajus
Creators: name: Tillier, Pierre
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Ascalaphidae
Libelloides
Libelloides coccajus

description: Libelloides coccajus (Denis & Schiffermüller, 1775)
Papilio coccajus Denis & Schiffermüller, 1775: 187.
CATÉGORIE ZOOGÉOGRAPHIQUE. — Espèce adriato-méditerranéenne expansive.
DISTRIBUTION DANS LE MERCANTOUR. — Saint-Dalmas-le-Selvage, Saint-Étienne-de-Tinée (Cocquempot & Chambon 1990).
description: Published as part of Tillier, Pierre, 2015, Raphidioptera et Neuroptera (Insecta, Neuropterida) du Parc national du Mercantour (France), pp. 581-594 in Zoosystema 37 (4) on page 591, DOI: 10.5252/z2015n4a4, http://zenodo.org/record/5156903
Nucleolar targeting in combination with radiation for cancer therapy.
Creators: name: Ismael, Mohammed
Publisher: name: University of Surrey
Year: 2020

description: An increased rate of cellular proliferation is a hallmark of cancer cells and may be accompanied by an increase in ribosome biogenesis and dysregulation in rRNA synthesis. In this regard CX-5461 has been developed as a novel RNA polymerase I inhibitor and is currently in Phase I/II clinical trials. The work described herein sets out to explore the use of this agent in combination with radiation therapy in solid cancer cell lines to understand the associated molecular mechanisms using this approach. Previous work has examined the CX-5461 in haematological malignancies and some solid cancers. Reports have shown that, treatment with CX-5461 induces potent anti-proliferative effects alongside induction of apoptosis in haematological malignancies. A panel of solid human tumour cell lines treated with CX-5461 indicated a broad spectrum of sensitivity (MTS Assay) with IC50 values ranging from 35nM to 1μM. The mode of cell death following CX-5461 exposure in the cancer cell lines studied was cell context dependent- either via autophagy (LC3I ® LC3II conversion alongside p62 sequestosome decrease) or via apoptosis (AnnexinV staining and late PARP cleavage). Treatment with CX-5461 also induced marked levels of DNA damage as detected through increased gH2AX foci staining. The presence of senescence marker β-galactosidase in CX-5461 treated cells indicates cell cycle arrest alongside the potent anti-proliferative effects of CX-5461 being highlighted through the clonogenic assays and decreased Ki-67 expression (flow cytometry). Through combination experiments involving CX-5461 and X-ray radiotherapy the current study has identified the highest levels of increased effectiveness in interactions between CX- 5461 and X-rays within the CaSki cervical cancer cell line. Highly significant effects were seen when low dose radiation and low dose CX-5461 were used together (combination index CI - < 0.2 with 6.25nM CX-5461 and 2Gy X-rays) through isobologram analysis. Cell cycle analysis of CaSki and A375 cells treated with single dose CX-5461 resulted in G2M cell cycle arrest and combination treatments with X-rays indicated cell cycle disruption with prolonged S-phase. The work described herein identifies the synergistic role of CX-5461 in combination with X- rays in solid cancers and may also inform the design of clinical trials of this novel agent.
Nachrichten
Creators: name: Hesse, Lisa
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Nachrichten aus der Region.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma
Creators: name: Ryall, Scott
name: Krishnatry, Rahul
name: Arnoldo, Anthony
name: Buczkowicz, Pawel
name: Mistry, Matthew
name: Siddaway, Robert
name: Ling, Cino
name: Pajovic, Sanja
name: Yu, Man
name: Rubin, Joshua B
name: Hukin, Juliette
name: Steinbok, Paul
name: Bartels, Ute
name: Bouffet, Eric
name: Tabori, Uri
name: Hawkins, Cynthia
Publisher: name: BioMed Central
Year: 2018

description: Paediatric brain tumours arising in the thalamus present significant diagnostic and therapeutic challenges to physicians due to their sensitive midline location. As such, genetic analysis for biomarkers to aid in the diagnosis, prognosis and treatment of these tumours is needed. Here, we identified 64 thalamic gliomas with clinical follow-up and characterized targeted genomic alterations using newly optimized droplet digital and NanoString-based assays. The median age at diagnosis was 9.25 years (range, 0.63–17.55) and median survival was 6.43 (range, 0.01–27.63) years. Our cohort contained 42 and 22 tumours reviewed as low and high grade gliomas, respectively. Five (12 %) low grade and 11 (50 %) high grade gliomas were positive for the H3F3A/HIST1H3B K27M (H3K27M) mutation. Kaplan-Meier survival analysis revealed significantly worse overall survival for patients harbouring the H3K27M mutation versus H3F3A/HIST1H3B wild type (H3WT) samples (log-rank p < 0.0001) with a median survival of 1.02 vs. 9.12 years. Mitogen-activated protein kinase (MAPK) pathway activation via BRAF or FGFR1 hotspot mutations or fusion events were detected in 44 % of patients, and was associated with long-term survival in the absence of H3K27M (log-rank p < 0.0001). Multivariate analysis demonstrated H3K27M status and high grade histology to be the most significant independent predictors of poor overall survival with hazard ratios of 6.945 and 7.721 (p < 0.0001), respectively. In contrast, MAPK pathway activation is a predictor of favourable patient outcome, although not independent of other clinical factors. Importantly, we show that low grade malignancies may harbour H3K27M mutations and that these tumours show a dismal survival compared to low grade H3WT cases. Our data strongly supports the inclusion of targeted genetic testing in childhood thalamic tumours to most accurately stratify patients into appropriate risk groups.
A comparison of retail trade and company sales staff perceptions of a trade based sales promotion
Creators: name: Luxton, Sandra
name: Romaniuk, Jenni
Publisher: name: Swinburne
Year: 2024

description: This paper presents a case study that was undertaken to understand the perceptions of both dealers and internal staff about a sales promotion that was employed by the company. In terms of general attitudes to promotions, sales representatives and dealers both saw promotions as purely sales driven, in terms of objectives and evaluations. However, senior staff saw sales promotions as having a relationship building role and as a motivator for staff. The internal staff we spoke to were sceptical about the effectiveness of such promotions with the sales reps perceiving that they would have achieved the sales anyway and the senior staff unsure how to assess these more abstract objectives. The key findings were the identification of the areas perceived by dealers and/or internal staff as impacting upon a sales promotion. These were: ability to attract attention, simplicity, having realistic targets, having good support material, appropriate incentives, efficient logistics, communication of benefits and sales support. It was also important to ensure that the goals of the promotion, as set by the company, were able to provide a benefit to the dealers.
Im Namen seiner Majestät: Welchen Einfluss haben Großunternehmen auf die Regierung?
Creators: name: Teufel, Mark
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Wenn man in Thailand die Frage stellt, welchen Einfluss die großen Unternehmen auf das Land haben, wird man zu der Erkenntnis gelangen, dass nur wenige dutzend Familienclans das Land unter sich aufgeteilt haben, und diesen Status Quo mit Zähnen und Klauen verteidigen.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Hyperspectral x-ray imaging : a comparison of iodinated and gold nanoparticle contrast media for the application of contrast-enhanced digital mammography.
Creators: name: March, Louise M.
Publisher: name: University of Surrey
Year: 2020

description: Dual energy imaging (DE) is a potential alternative breast imaging modality for patients with dense breasts. It utilises intravenous injection of contrast agent (CA) to highlight structures of interest, such as tumours. Following CA administration, images are acquired at two different energies, such that the change in attenuation of the CA across the energy range differs significantly from that of the background material, such as across its K-edge. Implementation of DE on a conventional detector requires two separate exposures, leading to a higher dose and possible patient movement between exposures, which can lead to incomplete background removal. The novelty of this work is the implementation of the DE algorithms using a hyperspectral energy-sensitive detector, HEXITEC, which gives a whole spectrum per pixel. This allows multiple energy images to be obtained simultaneously by integrating appropriate bands of the spectra acquired by each individual pixel, thereby providing a single-shot approach to DE. The ability to access a whole array of possible image combinations from a single exposure provides a powerful tool in determining the optimum beam parameters and energy ranges to produce the DE images. Two different contrast agents were compared: a clinical iodinated contrast agent and gold nanoparticles (AnNPs), which have the potential to be preferentially absorbed by tumours through targeting and functionalisation. Imaging performance was assessed for both contrast agents via reconstructed concentration calculations and CNR. The cell toxicity of each CA was also investigated using clonogenic assays to generate a cell survival curve following exposure to CA and radiation between 0-5 Gy. Both iodine and AuNPs showed good agreement with nominal values in terms of reconstructed concentration for a range of nominal concentrations (the reconstructed concentration of 200 mg/ml CA was 189 ±10 and 216 ±8 mg/ml for AuNPs and iodine respectively). Iodine outperformed AuNPs in terms of CNR. Toxicity results indicated a statistically significant decrease at the 68% confidence level in the alpha parameter of the linear quadratic dose curve with the addition of AuNPs but not with the addition of iodine, suggesting an increased toxicity with AuNPs (alpha values were found to be 0.46±1, 0.40 ±1 and 0.19±1/Gy⁻¹ for no CA, iodine and AuNPs respectively). Iodine outperformed AuNPs overall, but further work is required (including optimisation of the energy spectra) to allow the full potential of AuNPs to be determined.
Wenn der Bock zum Gärtner wird: Beeinflussung der Politik durch Geschäftsinteressen
Creators: name: Johannsen, Corinna
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Ein Beispiel par excellence: Mit der Wahl Thaksin Shinawatras im Jahr 2001 zum Premierminister Thailands wurde nicht nur einer der reichsten Männer an die Spitze der Regierung gewählt, sondern auch einer der mächtigsten und erfolgreichsten Unternehmer des Landes.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Recent development of fibre-optic two-photon fluorescence endoscopy devices
Creators: name: Gu, Min
Publisher: name: Swinburne
Year: 2024

description: We will give an overview of our recent work on fibre-optic two-photon fluorescence endoscopy devices. The main component of these devices is a single fibre coupler which acts as a low pass filter. The first device involves a lens-based probe head and the second includes a prism-based probe head.
Se il plurilinguismo entra in classe dalla porta principale
Creators: name: Sordella, Silvia
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2020

description:

This article presents an approach to analysis of attitudes within a focus group regarding plurilingualism enhancement. In specific, the teachers and their primary school classes were involved in the project Noi e le nostre lingue, realised by the University of Turin to fostering processes of language awareness, namely of éveil aux langues. In the illustrated theoretical and methodological systemic framework, the analysis of focus group conversation will show some clues to attitudes dimensions regarding knowledges, beliefs, expectations, emotions that support the evaluations and the behavioural intentions in this specific context.

description: EL.LE
La valutazione della complessità sintattica nella classe di lingua
Creators: name: Vedder, Ineke
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2020

description:

This paper aims to investigate how language teachers perceive syntactic complexity in L2 writing and to what extent teachers’ judgments are related to current theoretical views in the research literature on Second Language Acquisition (SLA). Sixteen L2 teachers were asked to evaluate the syntactic complexity of a sample of argumentative texts written by L2 university students of Italian. In the panel discussion that followed, teachers discussed the motivations behind their assigned scores and the feedback they had proposed. The results revealed that teachers tended to focus primarily on accuracy and comprehensibility, and much less on syntactic complexity. Teachers’ reflections appeared to be only partly aligned with existing theoretical views on syntactic complexity in the SLA literature.

description: EL.LE
Baustopp gestoppt oder: Wenn die Cashflow-Rechnung der Großkonzerne die Zukunft bestimmt
Creators: name: Pehrke, Jan
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Im thailändischen Map Ta Phut liegt eine der größten Industriezonen der Welt. Sie sollte noch größer werden, aber den Anwohnerinnen reichten schon die bisherigen Umweltbelastungen. Sie klagten, und im letzten Jahr gab ein Gericht ihnen Recht. Es stoppte 76 Bauvorhaben, dar unter zwei von BAYER. Jetzt aber steht alles wieder auf Anfang: Eine höhere Instanz hob das Urteil auf - lediglich zwei Unternehmungen fanden nicht die Gnade der RichterInnen.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Myrmeleon bore
Creators: name: Tillier, Pierre
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Myrmeleontidae
Myrmeleon
Myrmeleon bore

description: Myrmeleon bore (Tjeder, 1941)
Grocus bore Tjeder, 1941: 73.
CATÉGORIE ZOOGÉOGRAPHIQUE. — Espèce sibérienne expansive.
DISTRIBUTION DANS LE MERCANTOUR. — Saint-Étienne-de-Tinée (Cocquempot & Chambon 1990).
REMARQUE
Cette espèce à très large répartition n’est connue en France que de deux stations d’altitude, l’une pyrénéenne, l’autre alpine (Tillier 2010).
description: Published as part of Tillier, Pierre, 2015, Raphidioptera et Neuroptera (Insecta, Neuropterida) du Parc national du Mercantour (France), pp. 581-594 in Zoosystema 37 (4) on page 591, DOI: 10.5252/z2015n4a4, http://zenodo.org/record/5156903
Helmet regulation in Vietnam : Impact on health, equity and medical impoverishment
Creators: name: Olson, Zachary
name: Staples, John A.
name: Mock, Charles
name: Nguyen, Nam Phuong
name: Bachani, Abdulgafoor M.
name: Nugent, Rachel
name: Verguet, Stéphane
Publisher: name: BMJ Publishing Group
Year: 2022

description: Background Vietnam's 2007 comprehensive motorcycle helmet policy increased helmet use from about 30% of riders to about 93%. We aimed to simulate the effect that this legislation might have on: (a) road traffic deaths and non-fatal injuries, (b) individuals’ direct acute care injury treatment costs, (c) individuals’ income losses from missed work and (d) individuals’ protection against medical impoverishment. Methods and findings We used published secondary data from the literature to perform a retrospective extended cost-effectiveness analysis simulation study of the policy. Our model indicates that in the year following its introduction a helmet policy employing standard helmets likely prevented approximately 2200 deaths and 29 000 head injuries, saved individuals US$18 million in acute care costs and averted US$31 million in income losses. From a societal perspective, such a comprehensive helmet policy would have saved $11 000 per averted death or $830 per averted non-fatal injury. In terms of financial risk protection, traffic injury is so expensive to treat that any injury averted would necessarily entail a case of catastrophic health expenditure averted. Conclusions The high costs associated with traffic injury suggest that helmet legislation can decrease the burden of out-of-pocket payments and reduced injuries decrease the need for access to and coverage for treatment, allowing the government and individuals to spend resources elsewhere. These findings suggest that comprehensive motorcycle helmet policies should be adopted by low-income and middle-income countries where motorcycles are pervasive yet helmet use is less common.
Nachrichten
Creators: name: Müller, Michaela
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Nachrichten aus der Region.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?
Gestohlene Wahlen: Desillusionierung bei Hoffnung auf demokratischen Wandel in Burma
Creators: name: Horstmann, Alexander
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Der Autor kommentiert die Wahlen in Burma für die südostasien aus Maesot an der thailändisch-burmesischen Grenze.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 26 Nr. 4 (2010): Big is beautiful - Großkonzerne oder: Wer regiert das Land?