cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effect of iodinated contrast media on renal perfusion: A randomized comparison study in pigs using quantitative contrast-enhanced ultrasound (CEUS)
Creators: name: Lamby, Philipp
name: Jung, Friedrich
name: Graf, Stefanie
name: Schellenberg, Lotte
name: Falter, Johannes
name: Platz Batista da Silva, Natascha
name: Schreml, Stephan
name: Prantl, Lukas
name: Franke, Ralf P.
name: Jung, Ernst M.
Publisher: name: Universität Regensburg
Year: 2017
Subjects: subject: ACUTE KIDNEY INJURY; HUMAN ERYTHROCYTES; MICROCIRCULATION; MORPHOLOGY; DISEASE; OSMOLAR; ULTRASONOGRAPHY; DIFFERENTIATION; INTRAARTERIAL; MORTALITY;
subject: 610 Medizin

description: The administration of iodinated contrast media (CM) can cause microcirculatory disorder leading to acute renal dysfunction. In a prospective, randomized investigation two CM (Iodixanol vs Iopromide) were compared in 16 pigs. Each animal received 10 intra-aortal injections (5 ml Iodixanol or 4.32 ml Iopromide). Microcirculation was assessed using contrast-enhanced ultrasound (CEUS) directly on the kidney surface using time-to-peak (TTP) and blood-volume-analysis. Macroscopic observations were documented. Post mortem residual CM distribution in the kidneys was detected using X-ray. TTP was significantly prolonged over the descending vasa recta of the Iopromide group. This coincided with a visible marble-like pattern on the kidney surface occurring in 30 out of 80 Iopromide-injections but in 4 out of 80 Iodixanol-injections (p = 0.007). The blood volume over the entire kidney did not change after Iodixanol-application, but decreased by about 6.1% after Iopromide-application. The regional blood volume in the renal cortex showed a tendency to decrease by about 13.5% (p = 0.094) after Iodixanol-application, and clearly decreased by about 31.7% (p = 0.022) after Iopromide-application. The study revealed a consistent influence of repeated injections of two different CM on the kidney perfusion using three different imaging methods (CEUS analysis, macroscopic observation and X-ray analysis).
Alonella dadayi Birge 1910
Creators: name: Macêdo, Rafael Lacerda
name: Sousa, Francisco Diogo R.
name: Jesus, Sheila Bonfim de
name: Nunesmaia, Bárbara Janaina Bezerra
name: Branco, Christina Wyss Castelo
name: Elmoor-Loureiro, Lourdes M. A.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Branchiopoda
Diplostraca
Chydoridae
Alonella
Alonella dadayi

description: Alonella dadayi Birge, 1910.
(1) Small pond in Lençóis, 12°33’33”S 41°23’26”W, 29.vii.1985, coll. L.M.A. Elmoor-Loureiro (EL00422). (2) Pond at BR-020, Roda Velha, São Desidério, 12°47’18”S 45°57’06”W, col l. L.M.A. Elmoor-Loureiro (EL00479). (3) Pond on BA-697 road, near Nova Viçosa, 17°57’35”S 39°33’22”W, 22.i.1991, coll. L.M.A. Elmoor-Loureiro (EL03234). (4) Capivari Creek, Cruz das Almas, 12°38’52”S 39°05’52”W, 02.ix.1999, leg. Eduardo Mendes da Silva (EL01216). (5) Timeantube Pond, Praia do Forte, Mata de São João, 12°34’41”S 38°00’47”W, 12.vii.2002, coll. L.M.A. Elmoor-Loureiro (EL03266). (6) Formoso River, pond 1, head office of Trijunção Farm, Cocos, 14°49’02”S 45°58’35”W, 26.iv.2003, coll. L.M.A. Elmoor-Loureiro (EL02962), 19.x.2017, leg. Bárbara M. Fonseca (EL03294). (7) Formoso River, pond 2, Trijunção Farm, Cocos, 14°47’18”S 45°56’42”W, 27.iv.2003,coll. L.M.A. Elmoor-Loureiro (EL00423). (8) Pond at Santa Luzia Farm, Cocos, 14°54’47”S 45°58’19”W, 27.iv.2003, coll. L.M.A. Elmoor-Loureiro (EL02971). (9) Reservoir at Praia do Encanto Hotel, Morro de São Paulo, 13°26’05”S 38°54’34”W, 29.i.2004, coll. L.M.A. Elmoor-Loureiro (EL00424). (10) Mucugezinho River, Lençóis, 12°27’S 41°24’W, 14.x.2004, coll. Valéria Barros (EL03289). (11) Marsh at BA-001 road, approximately 23 Km south from Ilhéus, 15°0’59”S 38°59’56”W, 26.i.2006, coll. L.M.A. Elmoor-Loureiro (EL02849). (12) Pond at Tororomba Hotel, Ilhéus, 14°59’29”S 38°59’59”W, 27.i.2006, coll. L.M.A. Elmoor-Loureiro (EL03245). (13) Contas R iver, Itagibá, 14°06’– 14°11’S 39°39’– 39°47’W, x.2008 – vii.2009, coll. Sheila Bonfim de Jesus (SBJ). (14) Reservoir in Onça Stream, Bom Sucesso farm, Itagibá, 14°10’25”S 39°44’19”W, x.2008 – vii.2009, coll. Sheila Bonfim de Jesus (SBJ).
description: Published as part of Macêdo, Rafael Lacerda, Sousa, Francisco Diogo R., Jesus, Sheila Bonfim de, Nunesmaia, Bárbara Janaina Bezerra, Branco, Christina Wyss Castelo & Elmoor-Loureiro, Lourdes M. A., 2021, Cladocera (Crustacea, Branchiopoda) species of Bahia State, Brazil: a critical update on species descriptions, distributions, and new records, pp. 1-26 in Nauplius (e 2021011) (e 2021011) 29 on page 21, DOI: 10.1590/2358-2936e2021011, http://zenodo.org/record/10904828
Joint awareness in posttraumatic osteoarthritis of the knee: validation of the forgotten joint score in long term condition after tibial plateau fracture
Creators: name: Baumann, Florian
name: Weber, Johannes
name: Mahr, Daniel
name: Bäumlein, Martin
name: Kerschbaum, Maximilian
name: Müller, Karolina
name: Rillmann, Paavo
name: Nerlich, Michael
name: Loibl, Markus
Publisher: name: Universität Regensburg
Year: 2017
Subjects: subject: QUALITY-OF-LIFE; POPULATION-BASED COHORT; HEALTH-STATUS; LIGAMENT INJURIES; COSMIN CHECKLIST; OUTCOME MEASURES; SPORTS ACTIVITY; ARTHROPLASTY; ASSOCIATION; REPLACEMENT; Patient reported outcome measurement (PROM); Forgotten joint score (FJS); COSMIN checklist; Early osteoarthritis; Tibial plateau fracture
subject: 610 Medizin

description: Background: Evaluating patient-reported outcomes (PRO) in early osteoarthritis (OA) of the knee is difficult. Established measurement tools are focused on one of the two major patient groups in knee surgery: young, highly active patients, or older patients with advanced degenerative OA of the knee. Joint awareness in everyday life is a crucial criterion in measuring PRO. The purpose of this study was to validate a German version of the "Forgotten Joint Score" (FJS) in patients after surgical treatment of tibial plateau fractures. Methods: In this prospective cohort study, clinical and radiological outcomes data were collected from patients after surgical treatment of tibial plateau fractures following a skiing accident. Functional outcome questionnaires were administered including the FJS, the Lysholm-Score, the Tegner-Activity Scale (TAS), the EuroQol-5D (EQ 5-D), and a subjective rating of change. The validation study was carried out according to the COSMIN checklist protocol. The KLS was used to measure the presence and severity of OA on knee radiographs, and correlation with the FJS was measured. Results: Cronbach's alpha was .96 (95%-CI.92, .99) confirming good internal consistency. Test-retest reliability of the FJS was high with an ICC(67) = .91 (95%-CI.85, .95). Furthermore, no relevant floor or ceiling effects were observed. FJS significantly differed in patients with different OA degrees (p = .041). Symptomatic patients had significant lower FJS than asymptomatic patients (p < .001). Conclusions: This is the first study validating a disease-specific PRO, the FJS, in long-term outcomes after joint fracture. We demonstrated good psychometric properties and a significant correlation between the FJS and the radiologic degree of OA in patients with a history of tibial plateau fracture.
Thy-1 restricts steatosis and liver fibrosis in steatotic liver disease
Creators: name: Blank, Valentin
name: Karlas, Thomas Franz Clemens
name: Anderegg, Ulf
name: Wiegand, Johannes Tobias Martin
name: Arnold, Josias Lyndon
name: Bundalian, Linnaeus
name: Le Duc, Gabriela-Diana
name: Körner, Christiane
name: Ebert, Thomas
name: Saalbach, Anja
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Background and Aims: Steatotic liver disease (SLD) is generally considered to repre- sent a hepatic manifestation of metabolic syndrome and includes a disease spectrum comprising isolated steatosis, metabolic dysfunction-associated steatohepatitis, liver fibrosis and ultimately cirrhosis. A better understanding of the detailed underlying pathogenic mechanisms of this transition is crucial for the design of new and efficient therapeutic interventions. Thymocyte differentiation antigen (Thy-1, also known as CD90) expression on fibroblasts controls central functions relevant to fibrogen- esis, including proliferation, apoptosis, cytokine responsiveness, and myofibroblast differentiation. Methods: The impact of Thy-1 on the development of SLD and progression to fibrosis was investigated in high-fat diet (HFD)-induced SLD wild-type and Thy-1-deficient mice. In addition, the serum soluble Thy-1 (sThy-1) concentration was analysed in pa- tients with metabolic dysfunction-associated SLD stratified according to steatosis, inflammation, or liver fibrosis using noninvasive markers. Results: We demonstrated that Thy-1 attenuates the development of fatty liver and the expression of profibrogenic genes in the livers of HFD-induced SLD mice. Mechanistically, Thy-1 directly inhibits the profibrotic activation of nonparenchymal liver cells. In addition, Thy-1 prevents palmitic acid-mediated amplification of the in- flammatory response of myeloid cells, which might indirectly contribute to the pro- nounced development of liver fibrosis in Thy-1-deficient mice. Serum analysis of patients with metabolically associated steatotic liver disease syndrome revealed that sThy-1 expression is correlated with liver fibrosis status, as assessed by liver stiffness, the Fib4 score, and the NAFLD fibrosis score. Conclusion: Our data strongly suggest that Thy-1 may function as a fibrosis-protective factor in mouse and human SLD.
Attenuated lipotoxicity and apoptosis is linked to exogenous and endogenous augmenter of liver regeneration by different pathways
Creators: name: Weiss, Thomas S.
name: Lupke, Madeleine
name: Ibrahim, Sara
name: Buechler, Christa
name: Lorenz, Julia
name: Ruemmele, Petra
name: Hofmann, Ute
name: Melter, Michael
name: Dayoub, Rania
Publisher: name: Universität Regensburg
Year: 2017
Subjects: subject: MITOCHONDRIAL INTERMEMBRANE SPACE; ENDOPLASMIC-RETICULUM STRESS; INDUCED OBESE MICE; NONALCOHOLIC STEATOHEPATITIS; HEPATOCELLULAR-CARCINOMA; SULFHYDRYL OXIDASE; LIPIDOMIC ANALYSIS; METABOLIC DISEASE; FATTY; HEPATOPOIETIN;
subject: 610 Medizin

description: Nonalcoholic fatty liver disease (NAFLD) covers a spectrum from simple steatosis to nonalcoholic steatohepatitis (NASH) and cirrhosis. Free fatty acids (FFA) induce steatosis and lipo-toxicity and correlate with severity of NAFLD. In this study we aimed to investigate the role of exogenous and endogenous ALR (augmenter of liver regeneration) for FFA induced ER (endoplasmatic reticulum) - stress and lipoapoptosis. Primary human hepatocytes or hepatoma cells either treated with recombinant human ALR (rhALR, 15kDa) or expressing short form ALR (sfALR, 15kDa) were incubated with palmitic acid (PA) and analyzed for lipo-toxicity, -apoptosis, activation of ER-stress response pathways, triacylglycerides (TAG), mRNA and protein expression of lipid metabolizing genes. Both, exogenous rhALR and cytosolic sfALR reduced PA induced caspase 3 activity and Bax protein expression and therefore lipotoxicity. Endogenous sfALR but not rhALR treatment lowered TAG levels, diminished activation of ER-stress mediators C-Jun N-terminal kinase (JNK), X-box binding protein-1 (XBP1) and proapoptotic transcription factor C/EBP-homologous protein (CHOP), and reduced death receptor 5 protein expression. Cellular ALR exerts its lipid lowering and anti-apoptotic actions by enhancing FABP1, which binds toxic FFA, increasing mitochondrial beta-oxidation by elevating the mitochondrial FFA transporter CPT1 alpha, and decreasing ELOVL6, which delivers toxic FFA metabolites. We found reduced hepatic mRNA levels of ALR in a high fat diet mouse model, and of ALR and FOXA2, a transcription factor inducing ALR expression, in human steatotic as well as NASH liver samples, which may explain increased lipid deposition and reduced beta-oxidation in NASH patients. Present study shows that exogenous and endogenous ALR reduce PA induced lipoapoptosis. Furthermore, cytosolic sfALR changes mRNA and protein expression of genes regulating lipid metabolism, reduces ER-stress finally impeding progression of NASH.
Chydorus eurynotus Sars 1901
Creators: name: Macêdo, Rafael Lacerda
name: Sousa, Francisco Diogo R.
name: Jesus, Sheila Bonfim de
name: Nunesmaia, Bárbara Janaina Bezerra
name: Branco, Christina Wyss Castelo
name: Elmoor-Loureiro, Lourdes M. A.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Branchiopoda
Diplostraca
Chydoridae
Chydorus
Chydorus eurynotus

description: Chydorus eurynotus Sars,1901.
(1) Abaeté Pond, Salvador, 12°56’44”S 38°21’27”W, 01.viii.1981, coll. Janet W. Reid (EL02223). (2) Pedra do Cavalo Reservoir, Governador Mangabeira, 12°56’59”S 38°20’25”W, 11.vii.2001 and 27.iii.2002, leg. Eduardo Mendes da Silva (EL03252), 11.vii.2002, coll. L.M.A. Elmoor-Loureiro (EL00551). (3) Capivara Pond, Arembepe, Camaçari, 12°45’42”S 38°10’08”W, 12.vii.2002,coll. L.M.A.Elmoor-Loureiro (EL03261). (4) Timeantube Pond, Praia do Forte, Mata de São João, 12°34’41”S 38°00’47”W, 12.vii.2002, coll. L.M.A. Elmoor-Loureiro (EL03267).(5) Formoso River, pond 2, Trijunção Farm, Cocos, 14°47’18”S 45°56’42”W, 27.iv.2003, coll. L.M.A. Elmoor-Loureiro (EL03278). (6) Marsh at BA-001 road, approximately 23 Km south from Ilhéus, 15°0’59”S 38°59’56”W, 26.i.2006, coll. L.M.A. Elmoor-Loureiro (EL02561). (7) Contas River, Itagibá, 14°06’– 14°11’S 39°39’– 39°47’W, x.2008 – vii.2009, coll. Sheila Bonfim de Jesus (SBJ, EL03298). (8) Reservoir in Santa Rita Stream, Itagibá, 14°11’14”S 39°42’27”W, x.2008 – vii.2009, coll. Sheila Bonfim de Jesus (SBJ). (9) Reservoir in Onça Stream, Bom Sucesso farm, Itagibá, 14°10’25”S 39°44’19”W, x.2008 – vii.2009, coll. Sheila Bonfim de Jesus (SBJ).
description: Published as part of Macêdo, Rafael Lacerda, Sousa, Francisco Diogo R., Jesus, Sheila Bonfim de, Nunesmaia, Bárbara Janaina Bezerra, Branco, Christina Wyss Castelo & Elmoor-Loureiro, Lourdes M. A., 2021, Cladocera (Crustacea, Branchiopoda) species of Bahia State, Brazil: a critical update on species descriptions, distributions, and new records, pp. 1-26 in Nauplius (e 2021011) (e 2021011) 29 on page 22, DOI: 10.1590/2358-2936e2021011, http://zenodo.org/record/10904828
Impact of siRNA-mediated Cofilin-1 knockdown and obesity associated microenvironment on the motility of natural killer cells
Creators: name: Griesler, Bruno
name: Hölzel, Marijke
name: Oswald, Jana
name: Fänder, Johannes
name: Fischer, Trutz-Eckhardt Uwe Hermann Siegfried
name: Büttner, Maximilian
name: Quandt, Dagmar
name: Bähr, Ina
name: Jasinski-Bergner, Simon
name: Ivonne, Bazwinsky-Wutschke
name: Kielstein, Heike
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: The anti-tumor capacity of natural killer (NK) cells heavily relies on their ability to migrate towards their target cells. This process is based on dynamic actinrearrangement, so-called actin treadmilling, andis tightly regulated by proteins such as cofilin-1. The aim of the present study was to identify the role of cofilin-1 (CFL-1) in the migratory behavior of NK cells and to investigate a possible impact of an obesity-associated micromilieu on these cells, as it is known that obesity correlates with various impaired NK cell functions. CFL-1 was knocked-down via transfection of NK-92 cells with respective siRNAs. Obesity associated micromilieu was mimicked by incubation of NK-92 cells with adipocyte-conditioned medium from human preadipocyte SGBS cells or leptin. Effects on CFL-1 levels, the degree of phosphorylation to the inactive pCFL-1 as well as NK-92 cell motility were analyzed. Surprisingly, siRNA-mediated CFL-1 knockdown led to a significant increase of migration, as determined by enhanced velocity and accumulated distance of migration. No effect on CFL-1 nor pCFL-1 expression levels, proportion of phosphorylation and cell migratory behavior could be demonstrated under the influence of an obesity-associated microenvironment. In conclusion, the results indicate a significant effect of a CFL-1 knockdown on NK cell motility.
Evaluation of the new TNM-staging system for thymic malignancies: impact on indication and survival
Creators: name: Ried, Michael
name: Eicher, Maria-Magdalena
name: Neu, Reiner
name: Sziklavari, Zsolt
name: Hofmann, Hans-Stefan
Publisher: name: Universität Regensburg
Year: 2017
Subjects: subject: FORTHCOMING 8TH EDITION; LYMPH-NODE MAP; EPITHELIAL TUMORS; ADVANCED THYMOMA; INTERNATIONAL ASSOCIATION; PROGNOSTIC-FACTORS; PROJECT PROPOSALS; CLASSIFICATION; CARCINOMA; DATABASE; Thymoma; Thymic carcinoma; TNM staging; Masaoka-Koga; Staging system
subject: 610 Medizin

description: Background: The objective of this study is the evaluation of the Masaoka-Koga and the International Association for the Study of Lung Cancer (IASLC)/International Thymic Malignancy Interest Group (ITMIG) proposal for the new TNM-staging system on clinical implementation and prognosis of thymic malignancies. Methods: A retrospective study of 76 patients who underwent surgery between January 2005 and December 2015 for thymoma. Kaplan-Meier survival analysis was used to determine overall and recurrence-free survival rates. Results: Indication for surgery was primary mediastinal tumor (n = 55), pleural manifestation (n = 17), or mediastinal recurrence (n = 4) after surgery for thymoma. Early Masaoka-Koga stages I (n = 9) and II (n = 14) shifted to the new stage I (n = 23). Advanced stages III (Masaoka-Koga: n = 20; ITMIG/IASLC: n = 17) and IV (Masaoka-Koga: n = 33; ITMIG/IASLC: n = 35) remained nearly similar and were associated with higher levels of WHO stages. Within each staging system, the survival curves differed significantly with the best 5-year survival in early stages I and II (91%). Survival for stage IV (70 to 77%) was significantly better compared to stage III (49 to 54%). Early stages had a significant longer recurrence-free survival (86 to 90%) than advanced stages III and IV (55 to 56%). Conclusions: The proportion of patients with IASLC/ITMIG stage I increased remarkably, whereas the distribution in advanced stages III and IV was nearly similar. The new TNM-staging system presents a clinically useful and applicable system, which can be used for indication, stage-adapted therapy, and prediction of prognosis for overall and recurrence-free survival.
Simultaneous but independent spatial associations for pitch and loudness
Creators: name: Koch, Sarah
name: Schubert, Torsten
name: Blankenberger, Sven
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 150

description: For the auditory dimensions loudness and pitch a vertical SARC effect (Spatial Association of Response Codes) exists: When responding to loud (high) tones, participants are faster with top-sided responses compared to bottom-sided responses and vice versa for soft (low) tones. These effects are typically explained by two different spatial representations for both dimensions with pitch being represented on a helix structure and loudness being represented as spatially associated magnitude. Prior studies show incoherent results with regard to the question whether two SARC effects can occur at the same time as well as whether SARC effects interact with each other. Therefore, this study aimed to investigate the interrelation between the SARC effect for pitch and the SARC effect for loudness in a timbre discrimination task. Participants (N = 36) heard one tone per trial and had to decide whether the presented tone was a violin tone or an organ tone by pressing a top-sided or bottom-sided response key. Loudness and pitch were varied orthogonally. We tested the occurrence of SARC effects for pitch and loudness as well as their potential interaction by conducting a multiple linear regression with difference of reaction time (dRT) as dependent variable, and loudness and pitch as predictors. Frequentist and Bayesian analyses revealed that the regression coefficients of pitch and loudness were smaller than zero indicating the simultaneous occurrence of a SARC effects for both dimensions. In contrast, the interaction coefficient was not different from zero indicating an additive effect of both predictors.
"zpt_y0_y0.txt" of "A precise measurement of the Z-boson double-differential transverse momentum and rapidity distributions in the full phase space of the decay leptons with the ATLAS experiment at $\sqrt s$ = 8 TeV"
Creators: name: ATLAS Collaboration
Publisher: name: HEPData
Year: 2024

description: Correlation for $p_T$ cross section between 0.0 < |y| < 0.4 and 0.0 < |y| < 0.4
description: CERN-LHC. This paper presents for the first time a precise measurement of the production properties of the $Z$ boson in the full phase space of the decay leptons. This is in contrast to the many previous precise unfolded measurements performed in the fiducial phase space of the decay leptons. The measurement is obtained from proton--proton collision data collected by the ATLAS experiment in 2012 at $\sqrt{s} = 8$ TeV at the LHC and corresponding to an integrated luminosity of 20.2 fb$^{-1}$. The results, based on a total of 15.3 million $Z$-boson decays to electron and muon pairs, extend and improve a previous measurement of the full set of angular coefficients describing $Z$-boson decay. The double-differential cross-section distributions in $Z$-boson transverse momentum $p_T$ and rapidity $y$ are measured in the pole region, defined as $80 < m_{\ell\ell} < 100$ GeV, over the range $|y| < 3.6$. The total uncertainty of the normalised cross-section measurements in the peak region of the $p_T$ distribution is dominated by statistical uncertainties over the full range and increases as a function of rapidity from $0.5-1.0$% for $|y| < 2.0$ to $2-7$% at higher rapidities. The results for the rapidity-dependent transverse momentum distributions are compared to state-of-the-art QCD predictions, which combine in the best cases approximate N$^4$LL resummation with N$^3$LO fixed-order perturbative calculations. The differential rapidity distributions integrated over $p_T$ are even more precise, with accuracies from $0.2-0.3$% for $|y| < 2.0$ to $0.4-0.9$% at higher rapidities, and are compared to fixed-order QCD predictions using the most recent parton distribution functions. The agreement between data and predictions is quite good in most cases.
Chydorus nitidulus
Creators: name: Macêdo, Rafael Lacerda
name: Sousa, Francisco Diogo R.
name: Jesus, Sheila Bonfim de
name: Nunesmaia, Bárbara Janaina Bezerra
name: Branco, Christina Wyss Castelo
name: Elmoor-Loureiro, Lourdes M. A.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Branchiopoda
Diplostraca
Chydoridae
Chydorus
Chydorus nitidulus

description: Chydorus nitidulus (Sars, 1901).
(1) Pedra do Cavalo Reservoir, Governador Mangabeira, 12°56’59”S 38°20’25”W, 11.vii.2002, coll. L.M.A. Elmoor-Loureiro (EL03248). (2) Contas River, Itagibá, 14°06’–14°11’S 39°39’–39°47’W, x.2008 – vii.2009, coll. Sheila Bonfim de Jesus (SBJ, EL02869). (3) Reservoir in Santa Rita Stream, Itagibá, 14°11’14”S 39°42’27”W, x.2008 – vii.2009, coll. Sheila Bonfim de Jesus (SBJ). (4) Reservoir in Onça Stream, Bom Sucesso farm, Itagibá, 14°10’25”S 39°44’19”W, x.2008 – vii.2009, coll. Sheila Bonfim de Jesus (SBJ).
description: Published as part of Macêdo, Rafael Lacerda, Sousa, Francisco Diogo R., Jesus, Sheila Bonfim de, Nunesmaia, Bárbara Janaina Bezerra, Branco, Christina Wyss Castelo & Elmoor-Loureiro, Lourdes M. A., 2021, Cladocera (Crustacea, Branchiopoda) species of Bahia State, Brazil: a critical update on species descriptions, distributions, and new records, pp. 1-26 in Nauplius (e 2021011) (e 2021011) 29 on page 22, DOI: 10.1590/2358-2936e2021011, http://zenodo.org/record/10904828
The Use of Vote Counting Methods in General Elections: Application of Manual and Digital Methods in Providing Transparency
Creators: name: Wibowo, Rudi
name: Ratnawati, Ratnawati
name: Sosiawan, Edwi Arief
Publisher: name: Zenodo
Year: 2024

description: This material has been presented on 1st International Conference on Advanced Research in Sustainable Economic and Social Science 2024 October 23 - 24, 2024.
Promoting awareness and self-efficacy for culturally responsive teaching of pre-service teachers through the identity project : a mixed methods study
Creators: name: Pevec-Zimmer, Sharleen
name: Juang, Linda P.
name: Schachner, Maja
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 150

description: Culturally Responsive Teaching (CRT) provides a framework for teachers to include students’ ethnic-cultural identities in class, aiming to tackle issues of educational and societal inequity. This quasi-experimental mixed methods intervention study tested whether pre-service teachers attending a seminar based on an ethnic-cultural identity school intervention, the Identity Project, would show greater CRT self-efficacy and more positive beliefs about teaching in ethnic-culturally diverse classes, compared to a control group. Repeated measures ANCOVAs of survey data from 606 pre-service teachers in Germany indicated a stronger T1-T2 increase in confidence for interacting with ethnic-culturally diverse students and engaging in culture- and ethnic-related conversations in the intervention group. No significant time-by-group interactions emerged for other CRT facets. A content analysis of brief texts of pre-service teachers in the intervention group revealed they became more self-reflective about their own beliefs, learned about CRT practices for their own teaching, and gained confidence for including issues of ethnicity and culture in class. Yet, the complexity of ethnic-cultural diversity-related topics left some pre-service teachers feeling overwhelmed about how to adequately address ethnic-cultural diversity in the classroom. Overall, the Identity Project seminar raised pre-service teachers’ awareness and self-efficacy for engaging in CRT in the future.
False Belief Reasoning in Adults with and without Autistic Spectrum Disorder: Similarities and Differences
Creators: name: Sommer, Monika
name: Döhnel, Katrin
name: Jarvers, Irina
name: Blaas, Lore
name: Singer, Manuela
name: Nöth, Victoria
name: Schuwerk, Tobias
name: Rupprecht, Rainer
Publisher: name: Universität Regensburg
Year: 2018
Subjects: subject: TEMPORO-PARIETAL JUNCTION; ANTERIOR PREFRONTAL CORTEX; DEFAULT MODE NETWORK; ASPERGER-SYNDROME; SOCIAL COGNITION; MIND REGIONS; NEURAL BASIS; BRAIN; CHILDREN; TRUE; autism spectrum disorder; adults; false belief reasoning; theory of mind; mentalizing
subject: 610 Medizin

description: A central diagnostic criteria for autism spectrum disorder (ASD) is the qualitative impairment in reciprocal social interaction and a prominent hypotheses that tried to explain this impairment is the Theory of Mind (ToM) deficit hypotheses. On a behavioral level the critical test for having a ToM, the understanding of false beliefs (FB), is often used for testing ToM abilities in individuals with ASD. Investigating the neural underpinnings several neuroimaging studies revealed a network of areas involved in FB reasoning in neurotypical individuals. For ASD individuals the neural correlates of false belief processing are largely unknown. Using functional magnetic resonance imaging and an adapted unexpected transfer task, that makes it possible to distinguish between the computation of diverging beliefs and the selection of a belief-associated response, we investigated a group of adult high-functioning individuals with ASD (N = 15) and an age and IQ matched group of neurotypical adults (NT; N = 15). On the behavioral level we found no group differences. On the neural level, results were two-fold: In the story phase, in which participants had to compute whether the character's belief is congruent or incongruent to their own belief, there were no differences between neurotypical participants and those diagnosed with ASD. But, in the subsequent question phase, participants with ASD showed increased activity in the bilateral anterior prefrontal cortex, the left posterior frontal cortex, the left superior temporal gyrus, and the left temporoparietal area. These results suggest that during the story phase in which the participants processed observable actions the neural correlates do not differ between adult individuals with ASD and NT individuals. But in the question phase in which participants had to infer an unobservable mental state results revealed neural differences between the two groups. Possibly, these subtle neural processing differences may contribute to the fact that adult ASD individuals are able to master explicit false belief tasks but fail to apply their strategies during everyday social interaction.
German-wide prospective DACAPO cohort of survivors of the acute respiratory distress syndrome (ARDS): a cohort profile
Creators: name: Dodoo-Schittko, Frank
name: Brandstetter, Susanne
name: Brandl, Magdalena
name: Blecha, Sebastian
name: Quintel, Michael
name: Weber-Carstens, Steffen
name: Kluge, Stefan
name: Kirschning, Thomas
name: Muders, Thomas
name: Bercker, Sven
name: Ellger, Björn
name: Arndt, Christian
name: Meybohm, Patrick
name: Adamzik, Michael
name: Goldmann, Anton
name: Karagiannidis, Christian
name: Bein, Thomas
name: Apfelbacher, Christian
Publisher: name: Universität Regensburg
Year: 2018
Subjects: subject: QUALITY-OF-LIFE; PATIENT HEALTH QUESTIONNAIRE; CARE; VALIDITY; DETERMINANTS; METAANALYSIS; MULTICENTER; VALIDATION; MORTALITY; RETURN;
subject: 610 Medizin

description: Purpose While most research focuses on the association between medical characteristics and residual morbidity of survivors of the acute respiratory distress syndrome (ARDS), little is known about the relation between potentially modifiable intensive care unit (ICU) features and the course of health-related quality of life (HRQoL). Accordingly, the DACAPO study was set up to elucidate the influence of quality of intensive care on HRQoL and return to work (RtW) in survivors of ARDS. The continued follow-up of these former ICU patients leads to the establishment of the DACAPO (survivor) cohort. Participants Sixty-one ICUs all over Germany recruited patients with ARDS between September 2014 and April 2016. Inclusion criteria were: (1) age older than 18 years and (2) ARDS diagnosis according to the 'Berlin definition'. No further inclusion or exclusion criteria were applied. 1225 patients with ARDS could be included in the DACAPO ICU sample. Subsequently, the 876 survivors at ICU discharge form the actual DACAPO cohort. Findings to date The recruitment of the participants of the DACAPO cohort and the baseline data collection has been completed. The care-related data of the DACAPO cohort reveal a high proportion of adverse events (in particular, hypoglycaemia and reintubation). However, evidence-based supportive measures were applied frequently. Future plans Three months, 6 months and 1 year after ICU admission a follow-up assessment is conducted. The instruments of the follow-up questionnaires comprise the domains: (A) HRQoL, (B) RtW, (C) general disability, (D) psychiatric symptoms and (E) social support. Additionally, an annual follow-up of the DACAPO cohort focusing on HRQoL, psychiatric symptoms and healthcare utilisation will be conducted. Furthermore, several add-on projects affecting medical issues are envisaged.
Trocnadella suturalis Melichar
Creators: name: Dai, Wu
name: Dietrich, Christopher H.
name: Zhang, Yalin
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadellidae
Trocnadella
Trocnadella suturalis

description: Trocnadella suturalis (Melichar)
Macropsis suturalis Melichar,1902: 120
Macropsis melichari Oshanin, 1912:69 [nom.nov. for Macropsis scutellaris Melichar, 1902] Trocnadella melichari, Anufriev, 1987: 61
Trocnadella suturalis, Anufriev & Emeljanov, 1988: 83 Distribution. China (Fujian, Sichuan), Japan, Russia
description: Published as part of Dai, Wu, Dietrich, Christopher H. & Zhang, Yalin, 2015, A review of the leafhopper tribe Hyalojassini (Hemiptera: Cicadellidae: Iassinae) with description of new taxa, pp. 1-142 in Zootaxa 3911 (1) on page 35, DOI: 10.11646/zootaxa.3911.1.1, http://zenodo.org/record/253710
title: Activité du port de Saint-Malo – 1753 – Jersey
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: produits agroalimentaires
subject: alcool
subject: produits manufacturés
subject: textiles
subject: produits exotiques et ultramarins
subject: personnes
subject: produits combustibles

description: Cette fiche est issue de l’enquête menée par Jean Delumeau sur l’activité du port de Saint-Malo au 17e et 18e siècle. Cette fiche correspond à l’activité de l’année 1753 avec le port "Jersey"
description: Marchandises au départ de Saint-Malo : cidre ; savon ; toiles ; sucre ; eau de vie
description: Catégories de marchandises au départ de Saint-Malo : produits agroalimentaires ; alcool ; produits manufacturés ; textiles ; produits exotiques et ultramarins ; alcool
description: Marchandises arrivées à Saint-Malo : passagers ; charbon
description: Catégories de marchandises arrivées à Saint-Malo : personnes ; produits combustibles
description: Coverage: Grand commerce
description: Bibliographic citation: LE GALL, Jacqueline. Activités du port de Saint-Malo en 1753. DES : Histoire : Rennes : 1967 (Bibliothèque François-Lebrun, MH 1044)
description: date: Date de numérisation : 2021 à 2023
description: created: Années 1950-1960
Breitinger, Hilarius: Als Deutschenseelsorger in Posen und im Warthegau 1934-1945
Creators: name: Grunert, E.
Publisher: name: Ordenskorrespondenz
Year: 1970

description: Ordenskorrespondenz, Bd. 28 (1987): Ordenskorrespondenz: Zeitschrift für Fragen des Ordenslebens, Band 28
The electrophysiology of sequential adjustments of dual-task order coordination
Creators: name: Steinhauser, Robert
name: Steinhauser, Marco
name: Kübler, Sebastian
name: Schubert, Torsten
name: Strobach, Tilo
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 150

description: Performing two tasks simultaneously involves the coordination of their processing. This task coordination is particularly required in dual-task situations with varying task orders. When task order switches between subsequent trials, task order coordination leads to task order switch costs in comparison with order repetitions. However, it is open, whether task order coordination is exclusively controlled by the relation of the task orders of the current and the previous trials, or whether additional conditions such as task order before the previous trial leads to a behavioral and neural adjustment of task order coordination. To answer this question, we reanalyzed the data of two previously published experiments with order-cued dual-task paradigms. We did so with regard to whether task order switch costs and the EEG component order-switch positivity in the current dual-task trial would be modulated by order switches vs. repetitions in the previous trial (Trial N-1). In Experiment 1, we found a modulation of the task order switch costs in RTs and response reversals; these costs were reduced after an order switch compared with order repetitions in Trial N-1. In Experiment 2, there were no effects on the task order switch costs in the behavioral data. Nonetheless, we found the order-switch positivity to be strongly modulated by the order transition of the previous trial in both experiments. The order-switch positivity was substantially reduced if the previous trial was an order switch (compared to an order repetition) by itself. This implies that order coordination of dual tasks is adjusted in a gradual way depending on trial's history.
"zpt_y0_y1.txt" of "A precise measurement of the Z-boson double-differential transverse momentum and rapidity distributions in the full phase space of the decay leptons with the ATLAS experiment at $\sqrt s$ = 8 TeV"
Creators: name: ATLAS Collaboration
Publisher: name: HEPData
Year: 2024

description: Correlation for $p_T$ cross section between 0.0 < |y| < 0.4 and 0.4 < |y| < 0.8
description: CERN-LHC. This paper presents for the first time a precise measurement of the production properties of the $Z$ boson in the full phase space of the decay leptons. This is in contrast to the many previous precise unfolded measurements performed in the fiducial phase space of the decay leptons. The measurement is obtained from proton--proton collision data collected by the ATLAS experiment in 2012 at $\sqrt{s} = 8$ TeV at the LHC and corresponding to an integrated luminosity of 20.2 fb$^{-1}$. The results, based on a total of 15.3 million $Z$-boson decays to electron and muon pairs, extend and improve a previous measurement of the full set of angular coefficients describing $Z$-boson decay. The double-differential cross-section distributions in $Z$-boson transverse momentum $p_T$ and rapidity $y$ are measured in the pole region, defined as $80 < m_{\ell\ell} < 100$ GeV, over the range $|y| < 3.6$. The total uncertainty of the normalised cross-section measurements in the peak region of the $p_T$ distribution is dominated by statistical uncertainties over the full range and increases as a function of rapidity from $0.5-1.0$% for $|y| < 2.0$ to $2-7$% at higher rapidities. The results for the rapidity-dependent transverse momentum distributions are compared to state-of-the-art QCD predictions, which combine in the best cases approximate N$^4$LL resummation with N$^3$LO fixed-order perturbative calculations. The differential rapidity distributions integrated over $p_T$ are even more precise, with accuracies from $0.2-0.3$% for $|y| < 2.0$ to $0.4-0.9$% at higher rapidities, and are compared to fixed-order QCD predictions using the most recent parton distribution functions. The agreement between data and predictions is quite good in most cases.
Pfülf, Otto: Von den Herrlichkeiten der Kirchengeschichte, gesammelte Aufsätze 1889-1914
Creators: name: Decot, Rolf
Publisher: name: Ordenskorrespondenz
Year: 1970

description: Ordenskorrespondenz, Bd. 28 (1987): Ordenskorrespondenz: Zeitschrift für Fragen des Ordenslebens, Band 28
Quality of inter-hospital transportation in 431 transport survivor patients suffering from acute respiratory distress syndrome referred to specialist centers
Creators: name: Blecha, Sebastian
name: Dodoo-Schittko, Frank
name: Brandstetter, Susanne
name: Brandl, Magdalena
name: Dittmar, Michael
name: Graf, Bernhard M.
name: Karagiannidis, Christian
name: Apfelbacher, Christian
name: Bein, Thomas
Publisher: name: Universität Regensburg
Year: 2018
Subjects: subject: CRITICALLY-ILL PATIENTS; EXTRACORPOREAL MEMBRANE-OXYGENATION; ACUTE LUNG INJURY; INTENSIVE-CARE; OUTCOMES; VENTILATION; EXPERIENCE; PRESSURE; PROTOCOL; VOLUME; Inter-hospital transfer; ARDS; Quality of care
subject: 610 Medizin

description: The acute respiratory distress syndrome (ARDS) is a life-threatening condition. In special situations, these critically ill patients must be transferred to specialized centers for escalating treatment. The aim of this study was to evaluate the quality of inter-hospital transport (IHT) of ARDS patients. We evaluated medical and organizational aspects of structural and procedural quality relating to IHT of patients with ARDS in a prospective nationwide ARDS study. The qualification of emergency staff, the organizational aspects and the occurrence of critical events during transport were analyzed. Out of 1234 ARDS patients, 431 (34.9%) were transported, and 52 of these (12.1%) treated with extracorporeal membrane oxygenation. 63.1% of transferred patients were male, median age was 54 years, and 26.8% of patients were obese. All patients were mechanically ventilated during IHT. Pressure-controlled ventilation was the preferred mode (92.1%). Median duration to organize the IHT was 165 min. Median distance for IHT was 58 km, and median duration of IHT 60 min. Forty-two patient-related and 8 technology-related critical events (11.6%, 50 of 431 patients) were observed. When a critical event occurred, the PaO2/FiO(2) ratio before transport was significant lower (68 vs. 80 mmHg, p = 0.017). 69.8% of physicians and 86.7% of paramedics confirmed all transfer qualifications according to requirements of the German faculty guidelines (DIVI). The transport of critically ill patients is associated with potential risks. In our study the rate of patient- and technology-related critical events was relatively low. A severe ARDS with a PaO2/FiO(2) ratio < 70 mmHg seems to be a risk factor for the appearance of critical events during IHT. The majority of transport staff was well qualified. Time span for organization of IHT was relatively short. ECMO is an option to transport patients with a severe ARDS safely to specialized centers. Trial registration NCT02637011 (ClinicalTrials.gov, Registered 15 December 2015, retrospectively registered).
Extent of Resection in Newly Diagnosed Glioblastoma: Impact of a Specialized Neuro-Oncology Care Center
Creators: name: Haj, Amer
name: Doenitz, Christian
name: Schebesch, Karl-Michael
name: Ehrensberger, Denise
name: Hau, Peter
name: Putnik, Kurt
name: Riemenschneider, Markus
name: Wendl, Christina
name: Gerken, Michael
name: Pukrop, Tobias
name: Brawanski, Alexander
name: Proescholdt, Martin
Publisher: name: Universität Regensburg
Year: 2017
Subjects: subject: MALIGNANT GLIOMAS; SURVIVAL; SEARCH; resection; glioblastoma; fluorescence guidance; functional imaging; outcome
subject: 610 Medizin

description: Treatment of glioblastoma (GBM) consists of microsurgical resection followed by concomitant radiochemotherapy and adjuvant chemotherapy. The best outcome regarding progression free (PFS) and overall survival (OS) is achieved by maximal resection. The foundation of a specialized neuro-oncology care center (NOC) has enabled the implementation of a large technical portfolio including functional imaging, awake craniotomy, PET scanning, fluorescence-guided resection, and integrated postsurgical therapy. This study analyzed whether the technically improved neurosurgical treatment structure yields a higher rate of complete resection, thus ultimately improving patient outcome. Patients and methods: The study included 149 patients treated surgically for newly diagnosed GBM. The neurological performance score (NPS) and the Karnofsky performance score (KPS) were measured before and after resection. The extent of resection (EOR) was volumetrically quantified. Patients were stratified into two subcohorts: treated before (A) and after (B) the foundation of the Regensburg NOC. The EOR and the PFS and OS were evaluated. Results: Prognostic factors for PFS and OS were age, preoperative KPS, O-6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation status, isocitrate dehydrogenase 1 (IDH1) mutation status and EOR. Patients with volumetrically defined complete resection had significantly better PFS (9.4 vs. 7.8 months; p = 0.042) and OS (18.4 vs. 14.5 months; p = 0.005) than patients with incomplete resection. The frequency of transient or permanent postoperative neurological deficits was not higher after complete resection in both subcohorts. The frequency of complete resection was significantly higher in subcohort B than in subcohort A (68.2% vs. 34.8%; p = 0.007). Accordingly, subcohort B showed significantly longer PFS (8.6 vs. 7.5 months; p = 0.010) and OS (18.7 vs. 12.4 months; p = 0.001). Multivariate Cox regression analysis showed complete resection, age, preoperative KPS, and MGMT promoter status as independent prognostic factors for PFS and OS. Our data show a higher frequency of complete resection in patients with GBM after the establishment of a series of technical developments that resulted in significantly better PFS and OS without increasing surgery-related morbidity.
Secukinumab in adult patients with lichen planus : efficacy and safety results from the randomized placebo-controlled proof-of-concept PRELUDE study
Creators: name: Passeron, Thierry
name: Reinhardt, Maximilian
name: Ehst, Benjamin
name: Weiss, Jonathan
name: Sluzevich, Jason
name: Sticherling, Michael
name: Reygagne, Pascal
name: Wohlrab, Johannes
name: Hertl, Michael
name: Fazel, Nasim
name: Muscianisi, Elisa
name: Fan, Heng
name: Hampele, Isabelle
name: Compagno, Nicolò
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Background: Patients with lichen planus (LP) refractory to available therapies often experience a high disease burden, representing a population with a clear unmet need for new treatments. Objectives: To evaluate the efficacy and safety of secukinumab 300 mg over 32 weeks in adult patients with biopsy-proven cutaneous LP (CLP), mucosal LP (MLP) or lichen planopilaris (LPP) that is inadequately controlled by topical corticosteroids. Methods: PRELUDE was a randomized double-blind placebo-controlled phase II proof-of-concept study that enrolled patients with CLP, MLP or LPP. Eligible patients were randomized to either secukinumab 300 mg every 4 weeks for 32 weeks (SECQ4W) or placebo for 16 weeks followed by secukinumab 300 mg every 2 weeks (SECQ2W) for 16 weeks. The primary endpoint was achievement of the newly designed Investigator’s Global Assessment (IGA) score ≤ 2 at week 16. Results: Overall, 111 patients were randomized (n = 37 each) to CLP, MLP and LPP cohorts. As the proof-of-concept criteria were not met for any of the three cohorts, the primary objective was not met. A numerically higher proportion of patients achieved IGA ≤ 2 response at week 16 with SECQ4W vs. placebo in the MLP {37.5% [95% credibility interval (Crl) 20.3–57.2] vs. 23.1% (95% Crl 6.5–49.2)} and LPP cohorts [37.5% (95% Crl 20.2–57.3) vs. 30.8% (95% Crl 10.8–57.6)]. In the LPP cohort, a sustained response for IGA ≤ 2 from week 16 to week 32 was achieved with SECQ4W (week 16, 37.5%; week 32, 45.8%), and a substantial improvement was observed in IGA ≤ 2 response in patients from this cohort who switched from placebo (week 16, 30.8%) to SECQ2W after week 16 (week 32, 63.6%). The safety profile was consistent with the known profile of secukinumab and showed no new or unexpected signals. Conclusions: PRELUDE is the first randomized controlled basket trial evaluating interleukin (IL)-17A inhibition with secukinumab across three subtypes of LP. Secukinumab was well tolerated and safe, showing different response rates across the three subtypes, with numerical IGA improvements in MLP and LPP, and no response in CLP. The study raises the question of a differential role of IL-17A across LP subtypes. The novel IGA score showed significant correlation with both patient- and physician-reported outcome measurements.