cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A parallelogram chain designed to measure human joint motion
Creators: name: Cousins, Steven J.
Publisher: name: University of British Columbia
Year: 2010

description: This work is concerned with the problem of measuring the motion of a human joint under dynamic conditions. Past and present solutions to this problem are examined in a literature search. Criteria are established for the evaluation of designs, based on one year's clinical experience with a locally built device. A parallelogram chain is chosen from generated design alternatives using the established evaluation criteria. A prototype of the parallelogram chain is built. The chain casting has thin flexible plastic hinges. As each parallelogram scissors, unwanted translations are absorbed while three mutually perpendicular rotations pass through the chain unchanged. This allows the potentiometer motica transducers to be self-aligning with a joint. This will reduce patient fitting time and increase the reproduceability of results compared to previous devices. The chain is applicable to any large joint of the upper or lower limbs. A test rig, simulating human joint motion, is built. Test results indicate that the parallelogram chain can record dynamic motions of walking and slow running. The chain has a definable working volume within which low error and reproduceable results can be obtained. The chain produced best results, comparable or better than those obtained by other workers, when only one of the three measuring potentiometers was aligned with the corresponding joint axis of rotation. Errors caused by the joint simulator are explained and will facilitate redesign. The main source of measurement error is the hinge geometry and not the material properties of the chain. As a result, a new chain design is presented that should give reduced measurement errors.
"Bad Metal" Conductivity of Hard Core Bosons
Creators: name: Lindner, Netanel H.
name: Auerbach, Assa
Publisher: name: arXiv
Year: 2009
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Two dimensional hard core bosons suffer strong scattering in the high temperature resistive state at half filling. The dynamical conductivity is calculated using non perturbative tools such as continued fractions, series expansions and exact diagonalization. We find a large temperature range with linearly increasing resistivity and broad dynamical conductivity, signaling a breakdown of Boltzmann-Drude quasiparticle transport theory. At zero temperature, a high frequency peak in the dynamical conductivity appears above a "Higgs mass" gap, and corresponds to order parameter magnitude fluctuations. We discuss the apparent similarity between conductivity of hard core bosons and phenomenological characteristics of cuprates, including the universal scaling of Homes et. al. (Nature 430, 539 (2004)).
description: 15 pages, 9 figures
Deep Sequencing of Protease Inhibitor Resistant HIV Patient Isolates Reveals Patterns of Correlated Mutations in Gag and Protease
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: Computational Biology
Drug Resistance, Viral
HIV Infections
HIV Protease
HIV Protease Inhibitors
HIV-1
High-Throughput Nucleotide Sequencing
Humans
Mutation
gag Gene Products, Human Immunodeficiency Virus

description: While the role of drug resistance mutations in HIV protease has been studied comprehensively, mutations in its substrate, Gag, have not been extensively cataloged. Using deep sequencing, we analyzed a unique collection of longitudinal viral samples from 93 patients who have been treated with therapies containing protease inhibitors (PIs). Due to the high sequence coverage within each sample, the frequencies of mutations at individual positions were calculated with high precision. We used this information to characterize the variability in the Gag polyprotein and its effects on PI-therapy outcomes. To examine covariation of mutations between two different sites using deep sequencing data, we developed an approach to estimate the tight bounds on the two-site bivariate probabilities in each viral sample, and the mutual information between pairs of positions based on all the bounds. Utilizing the new methodology we found that mutations in the matrix and p6 proteins contribute to continued therapy failure and have a major role in the network of strongly correlated mutations in the Gag polyprotein, as well as between Gag and protease. Although covariation is not direct evidence of structural propensities, we found the strongest correlations between residues on capsid and matrix of the same Gag protein were often due to structural proximity. This suggests that some of the strongest inter-protein Gag correlations are the result of structural proximity. Moreover, the strong covariation between residues in matrix and capsid at the N-terminus with p1 and p6 at the C-terminus is consistent with residue-residue contacts between these proteins at some point in the viral life cycle.
Financial misstatement detection: a realistic evaluation
Creators: name: Zavitsanos, Elias
name: Mavroeidis, Dimitris
name: Bougiatiotis, Konstantinos
name: Spyropoulou, Eirini
name: Loukas, Lefteris
name: Paliouras, Georgios
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computation and Language (cs.CL)
subject: Machine Learning (cs.LG)
subject: Computational Finance (q-fin.CP)
subject: FOS: Computer and information sciences
subject: FOS: Economics and business

description: In this work, we examine the evaluation process for the task of detecting financial reports with a high risk of containing a misstatement. This task is often referred to, in the literature, as ``misstatement detection in financial reports''. We provide an extensive review of the related literature. We propose a new, realistic evaluation framework for the task which, unlike a large part of the previous work: (a) focuses on the misstatement class and its rarity, (b) considers the dimension of time when splitting data into training and test and (c) considers the fact that misstatements can take a long time to detect. Most importantly, we show that the evaluation process significantly affects system performance, and we analyze the performance of different models and feature types in the new realistic framework.
description: 9 pages, ICAIF2021
Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: AIDS Vaccines
Binding Sites
Genome, Viral
HIV Infections
HIV-1
Human Immunodeficiency Virus Proteins
Humans
Models, Molecular
Molecular Sequence Data
Sequence Alignment
Sequence Analysis, Protein

description: © 2015 Ferdinandy et al. The RV144 clinical trial showed the partial efficacy of a vaccine regimen with an estimated vaccine efficacy (VE) of 31% for protecting low-risk Thai volunteers against acquisition of HIV-1. The impact of vaccine-induced immune responses can be investigated through sieve analysis of HIV-1 breakthrough infections (infected vaccine and placebo recipients). A V1/V2-targeted comparison of the genomes of HIV-1 breakthrough viruses identified two V2 amino acid sites that differed between the vaccine and placebo groups. Here we extended the V1/V2 analysis to the entire HIV-1 genome using an array of methods based on individual sites, k-mers and genes/proteins. We identified 56 amino acid sites or “signatures” and 119 k-mers that differed between the vaccine and placebo groups. Of those, 19 sites and 38 k-mers were located in the regions comprising the RV144 vaccine (Env-gp120, Gag, and Pro). The nine signature sites in Env-gp120 were significantly enriched for known antibody-associated sites (p = 0.0021). In particular, site 317 in the third variable loop (V3) overlapped with a hotspot of antibody recognition, and sites 369 and 424 were linked to CD4 binding site neutralization. The identified signature sites significantly covaried with other sites across the genome (mean = 32.1) more than did non-signature sites (mean = 0.9) (p < 0.0001), suggesting functional and/or structural relevance of the signature sites. Since signature sites were not preferentially restricted to the vaccine immunogens and because most of the associations were insignificant following correction for multiple testing, we predict that few of the genetic differences are strongly linked to the RV144 vaccine-induced immune pressure. In addition to presenting results of the first complete-genome analysis of the breakthrough infections in the RV144 trial, this work describes a set of statistical methods and tools applicable to analysis of breakthrough infection genomes in general vaccine efficacy trials for diverse pathogens.
Comparative sequence analysis suggests a conserved gating mechanism for TRP channels
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: Allosteric Regulation
Amino Acid Sequence
Conserved Sequence
Ion Channel Gating
Models, Molecular
Molecular Sequence Data
Potassium Channels
Sequence Analysis
Transient Receptor Potential Channels

description: © 2015 Palovcak et al. The transient receptor potential (TRP) channel superfamily plays a central role in transducing diverse sensory stimuli in eukaryotes. Although dissimilar in sequence and domain organization, all known TRP channels act as polymodal cellular sensors and form tetrameric assemblies similar to those of their distant relatives, the voltagegated potassium (Kv) channels. Here, we investigated the related questions of whether the allosteric mechanism underlying polymodal gating is common to all TRP channels, and how this mechanism differs from that underpinning Kv channel voltage sensitivity. To provide insight into these questions, we performed comparative sequence analysis on large, comprehensive ensembles of TRP and Kv channel sequences, contextualizing the patterns of conservation and correlation observed in the TRP channel sequences in light of the well-studied Kv channels. We report sequence features that are specific to TRP channels and, based on insight from recent TRPV1 structures, we suggest a model of TRP channel gating that differs substantially from the one mediating voltage sensitivity in Kv channels. The common mechanism underlying polymodal gating involves the displacement of a defect in the H-bond network of S6 that changes the orientation of the pore-lining residues at the hydrophobic gate.
Graphene formation on SiC substrates
Creators: name: VanMil, Brenda L.
name: Myers-Ward, Rachael L.
name: Tedesco, Joseph L.
name: Eddy,, Charles R.
name: Jernigan, Glenn G.
name: Culbertson, James C.
name: Campbell, Paul M.
name: McCrate, Joseph M.
name: Kitt, Stephen A.
name: Gaskill, D. Kurt
Publisher: name: arXiv
Year: 2009
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Graphene layers were created on both C and Si faces of semi-insulating, on-axis, 4H- and 6H-SiC substrates. The process was performed under high vacuum (<10-4 mbar) in a commercial chemical vapor deposition SiC reactor. A method for H2 etching the on-axis sub-strates was developed to produce surface steps with heights of 0.5 nm on the Si-face and 1.0 to 1.5 nm on the C-face for each polytype. A process was developed to form graphene on the substrates immediately after H2 etching and Raman spectroscopy of these samples confirmed the formation of graphene. The morphology of the graphene is described. For both faces, the underlying substrate morphology was significantly modified during graphene formation; sur-face steps were up to 15 nm high and the uniform step morphology was sometimes lost. Mo-bilities and sheet carrier concentrations derived from Hall Effect measurements on large area (16 mm square) and small area (2 and 10 um square) samples are presented and shown to compare favorably to recent reports.
description: European Conference on Silicon Carbide and Related Materials 2008 (ECSCRM '08), 4 pages, 4 figures
Searches for Long Lived Neutral Particles
Creators: name: Meade, Patrick
name: Nussinov, Shmuel
name: Papucci, Michele
name: Volansky, Tomer
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: An intriguing possibility for TeV scale physics is the existence of neutral long lived particles (LOLIPs) that subsequently decay into SM states. Such particles are many cases indistinguishable from missing transverse energy (MET) at colliders. We propose new methods to search for these particles using neutrino telescopes. We study their detection prospects, assuming production either at the LHC or through dark matter (DM) annihilations in the Sun and the Earth. We find that the sensitivity for LOLIPs produced at the LHC is limited by luminosity and detection energy thresholds. On the other hand, in the case of DM annihilation into LOLIPs, the sensitivity of neutrino telescopes is promising and may extend beyond the reach of upcoming direct detection experiments. In the context of low scale hidden sectors weakly coupled to the SM, such indirect searches allow to probe couplings as small as 10^-15.
description: 22 pages, 6 figures
Electrolytically Generated Nanobubbles on HOPG Surfaces
Creators: name: Yang, Shangjiong
name: Tsai, Peichun
name: Kooij, E. Stefan
name: Prosperetti, Andrea
name: Zandvliet, Harold J. W.
name: Lohse, Detlef
Publisher: name: arXiv
Year: 2008
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Electrolysis of water is employed to produce surface nanobubbles on highly orientated pyrolytic graphite (HOPG) surfaces. Hydrogen (oxygen) nanobubbles are formed when the HOPG surface acts as negative (positive) electrode. Coverage and volume of the nanobubbles enhance with increasing voltage. The yield of hydrogen nanobubbles is much larger than the yield of oxygen nanobubbles. The growth of the individual nanobubbles during the electrolysis process is recorded in time with the help of AFM measurements and correlated with the total current. Both the size of the individual nanobubbles and the total current saturate after typical 1 minute; then the nanobubbles are in a dynamic equilibrium, meaning that they do not further grow, in spite of ongoing gas production and nonzero current. The surface area of nanobubbles shows a good correlation with the nanobubble volume growth rate, suggesting that either the electrolytic gas emerges directly at the nanobubbles' surface, or it emerges at the electrode's surface and then diffuses through the nanobubbles' surface. Moreover, the experiments reveal that the time constants of the current and the aspect ratio of nanobubbles are the same under all conditions. Replacement of pure water by water containing a small amount of sodium chloride (0.01 M) allows for larger currents, but qualitatively gives the same results.
description: Langmuir, in press
La hija de Cervantes: un dramma romantico inedito di Aureliano Fernández-Guerra y Orbe. Edizione critica e studio
Creators: name: Rioli, Silvia <1982>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2011
Subjects: L-LIN/05 Letteratura spagnola

description: Aureliano Fernandez-Guerra is known especially among Quevedo’s scholars because he published the first complete edition of Quevedo’s works. Few people know his plays and, for this reason, they have never been studied. These plays were written during his youth, when Fernández-Guerra hadn’t decided anything about his career yet. Therefore, these plays were always very important for him and, for this reason, he continued to correct and to revise them. Among them, the unpublished drama La hija de Cervantes (1840) was considered the most important play.
In this doctoral thesis I have tried to describe this Spanish author, especially focusing on theatre. In the first part I wrote about the life and the literary works, giving particularly importance to his plays that are La peña de los enamorados (1939), La hija de Cervantes (1840), Alonso Cano (1842) and La Ricahembra (1845), this last one written in collaboration with Manuel Tamayo y Baus, another important and famous playwright.
In the second part I deepened the study of La hija de Cervantes because it is a particular interesting drama: Aureliano Fernández-Guerra chose to represent the author of the Quixote as a character of his drama, especially dramatizing the most mysterious moments of his life, such as the Gaspar de Ezpeleta’s murder, his relationship with his daughter Isabel de Saavedra and his supposed love for a woman, whose existence his unknown. Besides, this drama is interesting because it is partially autobiographic: I found several letters and articles where it is emphasized the similarities between Cervantes’ and Aureliano’s life: both feel misunderstood and not appreciated by other people and both had to renounce a big love.
In the final part I presented the critical edition of La hija de Cervantes based on the last three manuscripts that are today at the Institut de Teatre in Barcelona. A wide philological note shows the transcription criterions.
The Edge-On Perspective of Bulgeless, Simple Disk Galaxies
Creators: name: Kautsch, Stefan J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: This review focuses on flat and superthin galaxies. These are edge-on bulgeless galaxies, which are composed of a simple, stellar disk. The properties of these simple disks are at the end of a continuum that extends smoothly from bulge-dominated disk galaxies to the pure disks. On average, simple disks are low-mass galaxies with low surface brightnesses, blue colors, and slow rotational velocities. Widely-accepted cosmological models of galaxy formation and evolution were challenged by a relatively large observed fraction of pure disk galaxies, and only very recent models can explain the existence of simple disk galaxies. This makes simple disks an optimal galaxy type for the study of galaxy formation in a hierarchical Universe. They enable us to analyze the environmental and internal influence on galaxy evolution, to study the stability of the disks, and to explain the nature and distribution of dark matter in galaxies. This review summarizes the current status of edge-on simple disk galaxies in the Universe.
description: 8 pages, 6 figures, PASP Invited IYA Review Article
Improvement of Morphology and Free Carrier Mobility through Argon-Assisted Growth of Epitaxial Graphene on Silicon Carbide
Creators: name: Tedesco, Joseph L.
name: VanMil, Brenda L.
name: Myers-Ward, Rachael L.
name: Culbertson, James C.
name: Jernigan, Glenn G.
name: Campbell, Paul M.
name: McCrate, Joseph M.
name: Kitt, Stephen A.
name: Eddy,, Charles R.
name: Gaskill, D. Kurt
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Graphene was epitaxially grown on both the C- and Si-faces of 4H- and 6H-SiC(0001) under an argon atmosphere and under high vacuum conditions. Following growth, samples were imaged with Nomarski interference contrast and atomic force microscopies and it was found that growth under argon led to improved morphologies on the C-face films but the Si-face films were not significantly affected. Free carrier transport studies were conducted through Hall effect measurements, and carrier mobilities were found to increase and sheet carrier densities were found to decrease for those films grown under argon as compared to high vacuum conditions. The improved mobilities and concurrent decreases in sheet carrier densities suggest a decrease in scattering in the films grown under argon.
description: 215th Meeting of the Electrochemical Society (ECS 215), 14 pages, 6 figures
R-BERT-CNN: Drug-target interactions extraction from biomedical literature
Creators: name: Aldahdooh, Jehad
name: Tanoli, Ziaurrehman
name: Tang, Jing
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computation and Language (cs.CL)
subject: Artificial Intelligence (cs.AI)
subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: In this research, we present our work participation for the DrugProt task of BioCreative VII challenge. Drug-target interactions (DTIs) are critical for drug discovery and repurposing, which are often manually extracted from the experimental articles. There are >32M biomedical articles on PubMed and manually extracting DTIs from such a huge knowledge base is challenging. To solve this issue, we provide a solution for Track 1, which aims to extract 10 types of interactions between drug and protein entities. We applied an Ensemble Classifier model that combines BioMed-RoBERTa, a state of art language model, with Convolutional Neural Networks (CNN) to extract these relations. Despite the class imbalances in the BioCreative VII DrugProt test corpus, our model achieves a good performance compared to the average of other submissions in the challenge, with the micro F1 score of 55.67% (and 63% on BioCreative VI ChemProt test corpus). The results show the potential of deep learning in extracting various types of DTIs.
Astrometric Calibration of the Beijing$-$Arizona Sky Survey
Creators: name: Peng, Xiyan
name: Qi, Zhaoxiang
name: Zhang, Tianmeng
name: Wu, Zhenyu
name: Zhou, Zhimin
name: Nie, Jundan
name: Zou, Hu
name: Fan, Xiaohui
name: Jiang, Linhua
name: McGreer, Ian
name: Yang, Jinyi
name: Dey, Arjun
name: Ma, Jun
name: Wang, Jiali
name: Schlegel, David
name: Zhou, Xu
Publisher: name: arXiv
Year: 2023
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We present the astrometric calibration of the Beijing-Arizona Sky Survey (BASS). The BASS astrometry was tied to the International Celestial Reference Frame via the \emph{Gaia} Data Release 2 reference catalog. For effects that were stable throughout the BASS observations, including differential chromatic refraction and the low charge transfer efficiency of the CCD, we corrected for these effects at the raw image coordinates. Fourth-order polynomial intermediate longitudinal and latitudinal corrections were used to remove optical distortions. The comparison with the \emph{Gaia} catalog shows that the systematic errors, depending on color or magnitude, are less than 2 milliarcseconds (mas). The position systematic error is estimated to be about $-0.01\pm0.7$ mas in the region between 30 and 60 degrees of declination and up to $-0.07 \pm 0.9$ mas in the region north of declination 60 degrees.
description: The article has been published on AJ, 11 pages, 12 figures
Calibrazione di modelli idrologici con algoritmi multiobiettivo
Creators: name: Lombardi, Laura <1975>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2011
Subjects: ICAR/02 Costruzioni idrauliche e marittime e idrologia

description: Traditional procedures for rainfall-runoff model calibration are generally based on the fit of the individual values of simulated and observed hydrographs. It is used here an alternative option that is carried out by matching, in the optimisation process, a set of statistics of the river flow. Such approach has the additional, significant advantage to allow also a straightforward regional calibration of the model parameters, based on the regionalisation of the selected statistics. The minimisation of the set of objective functions is carried out by using the AMALGAM algorithm, leading to the identification of behavioural parameter sets. The procedure is applied to a set of river basins located in central Italy: the basins are treated alternatively as gauged and ungauged and, as a term of comparison, the results obtained with a traditional time-domain calibration is also presented. The results show that a suitable choice of the statistics to be optimised leads to interesting results in real world case studies as far as the reproduction of the different flow regimes is concerned.
Combined computational and experimental analysis of a complex of ribonuclease III and the regulatory macrodomain protein, YmdB
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: RNase III
macrodomain
RNA processing
ADP-ribose
double-stranded RNA
post-transcriptional regulation

description: © 2014 The Authors. Ribonuclease III is a conserved bacterial endonuclease that cleaves double-stranded(ds) structures in diverse coding and noncoding RNAs. RNase III is subject to multiple levels of control that in turn confer global post-transcriptional regulation. The Escherichia coli macrodomain protein YmdB directly interacts with RNase III, and an increase in YmdB amount in vivo correlates with a reduction in RNase III activity. Here, a computational-based structural analysis was performed to identify atomic-level features of the YmdB-RNase III interaction. The docking of monomeric E. coli YmdB with a homology model of the E. coli RNase III homodimer yields a complex that exhibits an interaction of the conserved YmdB residue R40 with specific RNase III residues at the subunit interface. Surface Plasmon Resonance (SPR) analysis provided a KD of 61 nM for the complex, corresponding to a binding free energy (ΔG) of -9.9 kcal/mol. YmdB R40 and RNase III D128 were identified by in silico alanine mutagenesis as thermodynamically important interacting partners. Consistent with the prediction, the YmdB R40A mutation causes a 16-fold increase in KD (ΔΔG=+1.8 kcal/mol), as measured by SPR, and the D128A mutation in both RNase III subunits (D128A/D128′A) causes an 83-fold increase in KD (ΔΔG=+2.7 kcal/mol). The greater effect of the D128A/D128′A mutation may reflect an altered RNase III secondary structure, as revealed by CD spectroscopy, which also may explain the significant reduction in catalytic activity in vitro. The features of the modeled complex relevant to potential RNase III regulatory mechanisms are discussed.
Additional file 3 of Investigation of carbon and energy metabolic mechanism of mixotrophy in Chromochloris zofingiensis
Creators: name: Zhang, Zhao
name: Sun, Dongzhe
name: Cheng, Ka-Wing
name: Chen, Feng
Publisher: name: figshare
Year: 2021
Subjects: subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 3: Figure S2. KEGG enrichment of different expressed genes in M vs. P and M vs. H.
ENHANCING PATIENT EXPERIENCE THROUGH EFFICIENT PROCEDURAL FACILITATION AND DEPARTMENTAL INTEGRATION IN CLINICS: A REVIEW
Creators: name: Mohammed saad alarbash, Rashed mahdi alyami, Hassan Salman Ali Hurubi, Mohammed rabia Abdullah alqahtani, Ahad Hassan Ali Asiri, Thekra Mohammed Alquzi
Publisher: name: Zenodo
Year: 2024

description: Efficient procedural facilitation and seamless interdepartmental integration in medical clinics play a critical role in enhancing patient experience and optimizing healthcare delivery. This review explores strategies that streamline patient pathways while fostering collaboration between departments such as nursing, pharmacy, and laboratory services. Key challenges, including communication barriers and fragmented workflows, are addressed, and technological innovations such as electronic health records (EHRs) and patient portals are examined as solutions to bridge gaps. Additionally, the review highlights the role of lean management principles in eliminating inefficiencies and improving patient flow. By adopting patient-centered approaches and leveraging technology, medical clinics can reduce wait times, enhance care coordination, and ultimately improve patient satisfaction. Best practices and case studies are presented to illustrate the benefits of integrating departments and standardizing procedures for optimal patient outcomes. This review concludes with recommendations for healthcare administrators and providers to adopt comprehensive strategies that improve procedural efficiency and interdepartmental collaboration.

Keywords: Patient experience, procedural facilitation, interdepartmental integration, healthcare delivery, patient pathways, lean management, healthcare technology, care coordination, medical clinics, patient satisfaction.
Was reionization complete by z ~ 5-6?
Creators: name: Mesinger, Andrei
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: It is generally taken for granted that reionization has completed by z=6, due to the detection of flux in the Lyman alpha forest at redshifts z<6. However, since reionization is expected to be highly inhomogeneous, much of the spectra pass through just the ionized component of the intergalactic medium (IGM) even for non-negligible values of the volume-weighted mean neutral hydrogen fraction, x_HI. We study the expected signature of an incomplete reionization at z ~ 5--6, using very large-scale (2 Gpc) seminumeric simulations. We find that ruling out an incomplete reionization is difficult at these redshifts since: (1) quasars reside in biased regions of the ionization field, with fewer surrounding HI patches than implied by the global mean, x_H; (2) absorption from the residual neutral hydrogen inside the ionized IGM generally dominates over the absorption from the remaining HI regions; (3) modeling the Lyman alpha forest and its redshift evolution even in just the ionized IGM is very difficult, and nearly impossible to do a priori. We propose using the fraction of pixels which are dark as a simple, nearly model-independent upper limit on x_HI. Alternately, the size distribution of regions with no detectable flux (dark gaps) can be used to place a more model dependent constraint. Either way, the current sample of quasars is statistically insufficient to constrain x_HI at z~6 to even the 10 per cent level. At z~5, where there are more available sightlines and the forest is less dark, constraining x_HI < 0.1 might be possible given a large dynamic range from very deep spectra and/or the Lyman beta forest. We conclude with the caution against over-interpreting the observations. There is currently no direct evidence that reionization was complete by z ~ 5-6.
description: 10 pages, 8 figures, submitted to MNRAS
Delayed feedback induced directed inertia particle transport in a washboard potential
Creators: name: Hennig, D.
name: Schimansky-Geier, L.
name: Hänggi, P.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider motion of an underdamped Brownian particle in a washboard potential that is subjected to an unbiased time-periodic external field. While in the limiting deterministic system in dependence of the strength and phase of the external field directed net motion can exist, for a finite temperature the net motion averages to zero. Strikingly, with the application of an additional time-delayed feedback term directed particle motion can be accomplished persisting up to fairly high levels of the thermal noise. In detail, there exist values of the feedback strength and delay time for which the feedback term performs oscillations that are phase locked to the time-periodic external field. This yields an effective biasing rocking force promoting periods of forward and backward motion of distinct duration, and thus directed motion. In terms of phase space dynamics we demonstrate that with applied feedback desymmetrization of coexisting attractors takes place leaving the ones supporting either positive or negative velocities as the only surviving ones. Moreover, we found parameter ranges for which in the presence of thermal noise the directed transport is enhanced compared to the noise-less case.
Applying Recovery Biomarkers to Calibrate Self-Report Measures of Energy and Protein in the Hispanic Community Health Study/Study of Latinos
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: biological markers
calibration equations
dietary measurement error
Hispanics/Latinos
24-hour dietary recall
nutrition assessment

description: © The Author 2015. We investigated measurement error in the self-reported diets of US Hispanics/Latinos, who are prone to obesity and related comorbidities, by background (Central American, Cuban, Dominican, Mexican, Puerto Rican, and South American) in 2010-2012. In 477 participants aged 18-74 years, doubly labeled water and urinary nitrogen were used as objective recovery biomarkers of energy and protein intakes. Self-report was captured from two 24-hour dietary recalls. All measures were repeated in a subsample of 98 individuals. We examined the bias of dietary recalls and their associations with participant characteristics using generalized estimating equations. Energy intake was underestimated by 25.3% (men, 21.8%; women, 27.3%), and protein intake was underestimated by 18.5% (men, 14.7%; women, 20.7%). Protein density was overestimated by 10.7% (men, 11.3%; women, 10.1%). Higher body mass index and Hispanic/Latino background were associated with underestimation of energy (P < 0.05). For protein intake, higher body mass index, older age, nonsmoking, Spanish speaking, and Hispanic/Latino background were associated with underestimation (P < 0.05). Systematic underreporting of energy and protein intakes and overreporting of protein density were found to vary significantly by Hispanic/Latino background. We developed calibration equations that correct for subject-specific error in reporting that can be used to reduce bias in diet-disease association studies.
Distantly Supervised Semantic Text Detection and Recognition for Broadcast Sports Videos Understanding
Creators: name: Shah, Avijit
name: Biswas, Topojoy
name: Ramadoss, Sathish
name: Shah, Deven Santosh
Publisher: name: arXiv
Year: 2021
Subjects: subject: Multimedia (cs.MM)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Information Retrieval (cs.IR)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: H.5.1; I.4.8; I.2.10; I.2.7; I.4.9

description: Comprehensive understanding of key players and actions in multiplayer sports broadcast videos is a challenging problem. Unlike in news or finance videos, sports videos have limited text. While both action recognition for multiplayer sports and detection of players has seen robust research, understanding contextual text in video frames still remains one of the most impactful avenues of sports video understanding. In this work we study extremely accurate semantic text detection and recognition in sports clocks, and challenges therein. We observe unique properties of sports clocks, which makes it hard to utilize general-purpose pre-trained detectors and recognizers, so that text can be accurately understood to the degree of being used to align to external knowledge. We propose a novel distant supervision technique to automatically build sports clock datasets. Along with suitable data augmentations, combined with any state-of-the-art text detection and recognition model architectures, we extract extremely accurate semantic text. Finally, we share our computational architecture pipeline to scale this system in industrial setting and proposed a robust dataset for the same to validate our results.
description: 9 pages, 7 figures and 6 tables. To be published in the proceedings of ACM Multimedia 21, Industrial Track, held from October 20-24 in China
L'attività pionieristica della Scuola bolognese nello studio e nell'utilizzo del cemento armato: 1875 - 1924. Tecniche costruttive e tipologie architettoniche
Creators: name: Predari, Giorgia <1978>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2011
Subjects: ICAR/10 Architettura tecnica

description: La ricerca mira ad indagare l’origine della Scuola ingegneristica bolognese ed il ruolo che essa ha avuto durante i suoi primi 50 anni di attività nella diffusione del calcestruzzo armato in Italia, ed in particolare nella città di Bologna, sia dal punto di vista teorico che architettonico. Il processo di sviluppo del cemento armato è stato indagato secondo i percorsi tipici della scienza e della tecnica: teoria e pratica appaiono nel periodo di sperimentazione del materiale assai lontane; soltanto grazie alla comprensione delle sue potenzialità costruttive e del modo di sfruttarle al meglio, esse iniziano a convergere. L’interesse specifico per la Scuola bolognese va quindi a collocarsi all’interno di un panorama assai più ampio, con l’obiettivo di comprendere se, e fino a quando, le due discipline proseguono lungo strade parallele o se, al contrario, esse godono di reciproche influenze.
Van der Waals Heterostructure Polaritons with moiré-Induced Nonlinearity
Creators: name: Zhang, Long
name: Wu, Fengcheng
name: Hou, Shaocong
name: Zhang, Zhe
name: Chou, Yu-Hsun
name: Watanabe, Kenji
name: Taniguchi, Takashi
name: Forrest, Stephen R.
name: Deng, Hui
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Controlling matter-light interactions with cavities is of fundamental importance in modern science and technology. It is exemplified in the strong-coupling regime, where matter-light hybrid modes form, with properties controllable via the photon component on the optical-wavelength scale. In contrast, matter excitations on the nanometer scale are harder to access. In two-dimensional van der Waals heterostructures, a tunable moiré lattice potential for electronic excitations may form, enabling correlated electron gases in lattice potentials. Excitons confined in moiré lattices have also been reported, but cooperative effects have been elusive and interactions with light have remained perturbative. Here, integrating MoSe$_{2}$-WS$_{2}$ heterobilayers in a microcavity, we establish cooperative coupling between moiré-lattice excitons and microcavity photons up to liquid-nitrogen temperature, thereby integrating into one platform versatile control over both matter and light. The density dependence of the moiré polaritons reveals strong nonlinearity due to exciton blockade, suppressed exciton energy shift, and suppressed excitation-induced dephasing, all of which are consistent with the quantum-confined nature of the moiré excitons. Such a moiré polariton system combines strong nonlinearity and microscopic-scale tuning of matter excitations with the power of cavity engineering and long range coherence of light, providing a new platform for collective phenomena from tunable arrays of quantum emitters.
An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: rectal cancer
integrated approach
biological network
prognostic
predictive

description: Introduction: Colorectal cancer is the third most common cancer in the world, a small fraction of which is represented by locally advanced rectal cancer (LARC). If not medically contraindicated, preoperative chemoradiotherapy, represent the standard of care for LARC patients. Unfortunately, patients shows a wide range of response rates in which approximately 20% has a complete pathological response, whereas in 20 to 40% the response is poor or absent. Results: The following specific gene signature, able to discriminate responders' patients from non-responders, were founded: AKR1C3, CXCL11, CXCL10, IDO1, CXCL9, MMP12 and HLA-DRA. These genes are mainly involved in immune system pathways and interact with drugs traditionally used in the adjuvant treatment of rectal cancer. Discussion: The present study suggests that new ideas for therapy could be found not only limited to studying genes differentially expressed between the two groups of patients but deepening the mechanisms, associated to response, in which they are involved. Methods: Gene expression studies performed by: Agostini et al., Rimkus et al. and Kim et al. have been merged through a meta-analysis of the raw data. Gene expression data-sets have been processed using A-MADMAN. Common differentially expressed gene (DEG) were identified through SAM analysis. To further characterize the identified DEG we deeply investigated its biological role using an integrative computational biology approach.
Interface-enhanced ferromagnetism with long-distance effect in van der Waals semiconductor
Creators: name: Zhu, Wenxuan
name: Song, Cheng
name: Han, Lei
name: Bai, Hua
name: Wang, Qian
name: Yin, Siqi
name: Huang, Lin
name: Chen, Tongjin
name: Pan, Feng
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Ferromagnetic semiconductors discovered in two-dimensional (2D) materials open an avenue for highly integrated and multifunctional spintronics. The Curie temperature (TC) of existed 2D ferromagnetic semiconductors is extremely low and the modulation effect of their magnetism is limited compared with their 2D metallic counterparts. The interfacial effect was found to effectively manipulate the three-dimensional magnetism, providing a unique opportunity for tailoring the 2D magnetism. Here we demonstrate that the TC of 2D ferromagnetic semiconductor Cr2Ge2Te6 can be enhanced by 130% (from ~65 K to above 150 K) when adjacent to a tungsten layer. The interfacial W-Te bonding contributes to the TC enhancement with a strong perpendicular magnetic anisotropy (PMA), guaranteeing an efficient magnetization switching by the spin-orbit torque with a low current density at 150 K. Distinct from the rapid attenuation in conventional magnets, the interfacial effect exhibits a weak dependence on Cr2Ge2Te6 thickness and a long-distance effect (more than 10 nanometers) due to the weak interlayer coupling inherent to 2D magnets. Our work not only reveals a unique interfacial behavior in 2D materials, but also advances the process towards practical 2D spintronics.
description: 22pages, 4 figures, accepted by Adv. Funct. Mater
Mid-IR observations of circumstellar disks -- Part III: A mixed sample of PMS stars and Vega-type objects
Creators: name: Schuetz, O.
name: Meeus, G.
name: Sterzik, M. F.
name: Peeters, E.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present new mid-infrared spectra for a sample of 15 targets (1 FU Orionis object, 4 Herbig Ae stars, 5 T Tauri stars and 5 Vega type stars), obtained with the TIMMI2 camera at La Silla Observatory (ESO). Three targets are members of the beta Pic moving group (HD 155555, HD 181296 and HD 319139). PAH bands are observed towards the T Tauri star HD 34700 and the Herbig Ae star PDS 144 N. For HD 34700, the band profiles indicate processed PAHs. The spectrum of the Vega-type object eta Corvi (HD 109085), for which a resolved disk at sub-mm wavelengths is known, is entirely stellar between 8--13 micron. Similarly, no indication for circumstellar matter at mid-infrared wavelengths is found towards the Vega-like stars HD 3003, HD 80951, HD 181296 and, surprisingly, the T Tauri system HD 155555. The silicate emission features of the remaining eight sources are modelled with a mixture of silicates of different grain sizes and composition. Unprocessed dust dominates FU Ori, HD 143006 and CD-43 344. Large amorphous grains are the main dust component around HD 190073, HD 319139, KK Oph and PDS 144 S. Both small grains and crystalline dust is found for the Vega-type HD 123356, with a dominance of small amorphous grains. We show that the infrared emission of the binary HD 123356 is dominated by its late-type secondary, but optical spectroscopy is still required to confirm the age of the system and the spectral class of the companion. For most targets this is their first mid-infrared spectroscopic observation. We investigate trends between stellar, disk and silicate properties and confirm correlations of previous studies. Several objects present an exciting potential for follow-up high-resolution disk studies.
description: Accepted for publication in A&A
Bounds on new light particles from high-energy and very small momentum transfer np elastic scattering data
Creators: name: Kamyshkov, Yuri
name: Tithof, Jeffrey
name: Vysotsky, Mikhail
Publisher: name: arXiv
Year: 2008
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We found that spin-one new light particle exchanges are strongly bounded by high-energy and small momentum transfer np elastic scattering data; the analogous bound for a scalar particle is considerably weaker, while for a pseudoscalar particle no bounds can be set. These bounds are compared with the bounds extracted from low-energy n-Pb scattering experiments and from the bounds of pi0 and K+ meson decays.
description: 16 pages with 4 figures; v2, v3 have minor grammatical changes
Cluster magnetic octupole induced out-of-plane spin polarization in antiperovskite antiferromagnet
Creators: name: You, Yunfeng
name: Bai, Hua
name: Feng, Xiaoyu
name: Fan, Xiaolong
name: Han, Lei
name: Zhou, Xiaofeng
name: Zhou, Yongjian
name: Zhang, Ruiqi
name: Chen, Tongjin
name: Pan, Feng
name: Song, Cheng
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Out-of-plane spin polarization σ_z has attracted increasing interests of researchers recently, due to its potential in high-density and low-power spintronic devices. Noncollinear antiferromagnet (AFM), which has unique 120° triangular spin configuration, has been discovered to possess σ_z. However, the physical origin of σ_z in noncollinear AFM is still not clear, and the external magnetic field-free switching of perpendicular magnetic layer using the corresponding σ_z has not been reported yet. Here, we use the cluster magnetic octupole in antiperovskite AFM Mn3SnN to demonstrate the generation of σ_z. σ_z is induced by the precession of carrier spins when currents flow through the cluster magnetic octupole, which also relies on the direction of the cluster magnetic octupole in conjunction with the applied current. With the aid of σ_z, current induced spin-orbit torque (SOT) switching of adjacent perpendicular ferromagnet is realized without external magnetic field. Our findings present a new perspective to the generation of out-of-plane spin polarizations via noncollinear AFM spin structure, and provide a potential path to realize ultrafast high-density applications.
description: 23 pages, 4 figures, accepted by Nat. Commun