cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
WIYN Open Cluster Study 1: Deep Photometry of NGC 188
Creators: name: von Hippel, Ted
name: Sarajedini, Ata
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have employed precise V and I photometry of NGC 188 at WIYN to explore the cluster luminosity function (LF) and study the cluster white dwarfs (WDs). Our photometry is offset by V = 0.052 (fainter) from Sandage (1962) and Eggen & Sandage (1969). All published photometry for the past three decades have been based on these two calibrations, which are in error by 0.05 +- 0.01. We employ the Pinsonneault etal (1998) fiducial main sequence to derive a cluster distance modulus of 11.43 +- 0.08. We report observations that are >= 50% complete to V = 24.6 and find that the cluster central-field LF peaks at M_I ~ 3 to 4. This is unlike the solar neighborhood LF and unlike the LFs of dynamically unevolved portions of open and globular clusters, which rise continuously until M_I ~ 9.5. Although we find that >= 50% of the unresolved cluster objects are multiple systems, their presence cannot account for the shape of the NGC 188 LF. For theoretical reasons (Terlevich 1987; Vesperini & Heggie 1997) having to do with the survivability of NGC 188 we believe the cluster is highly dynamically evolved and that the missing low luminosity stars are either in the cluster outskirts or have left the cluster altogether. We identify nine candidate WDs, of which we expect three to six are bona fide cluster WDs. The luminosities of the faintest likely WD indicates an age (Bergeron, Wesemael, & Beauchamp 1995) of 1.14 +- 0.09 Gyrs. This is a lower limit to the cluster age and observations probing to V = 27 or 28 will be necessary to find the faintest cluster WDs and independently determine the cluster age. While our age limit is not surprising for this ~6 Gyr old cluster, our result demonstrates the value of the WD age technique with its very low internal errors. (abridged)
description: 26 pages, uuencoded gunzip'ed latex + 16 postscrip figures, to be published in AJ
Reminiscences of Richard Walker Bolling, 1983
Publisher: name: Columbia University
Year: 2021
Subjects: Legislators--United States
World War, 1939-1945
Civil rights--United States

description: Background and early education; Army duty in Pacific, 1941-1946, on General MacArthur's staff; vice chairman of American Veterans Committee, 1946-1947; election to United States House of Representatives, 1948; political problems of first term; functioning of the House of Representatives, 1948-1982: committee work on Banking, Joint Economic and Rules committees, civil rights; legislative strategy of Kennedy administration; impressions of Presidents Harry Truman, Lyndon Johnson, and John F. Kennedy; Sam Rayburn and other political leaders
Additional file 1 of Patients’ views of shared decision making in inflammatory bowel disease: a survey in China
Creators: name: Xu, Dingting
name: Zhang, Hanyun
name: Chen, Yan
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1. Questionnaire on IBD patients' views of shared decision making (SDM).
Information processing in molecular motifs and signal transduction
Creators: name: Mc Mahon, Siobhan
Publisher: name: Imperial College London
Year: 2015

description: Sensing and responding to the environment is a crucial function in all living organisms. The molecular mechanisms that facilitate these essential processes are however subject to a range of random effects and stochastic processes, which jointly affect the reliability of information transmission between receptors and e.g. the physiological downstream response. We employ an information theoretic framework to capture and characterise how extrinsic and intrinsic noise affect the transmission of signals along simple motifs of molecular interaction networks, and cell fate decision making pathways. We observe that the biomolecular information processing efficiency is profoundly but differently affected by the various sources of noise. In particular extrinsic variability is apt to generate “apparent” information that can in extreme cases mask the actual information that would flow between the different molecular components. We show how this artificial inflation in information arises, and how the effects of different types of noise alone and in combination can be understood. By applying the same approach to the ERK signalling pathway, we determine the best mechanistic model for this system in question and shed light on the noise filtering capabilities of the system. We also consider the pathway under conditions of abnormal regulation, similar to those associated with tumerogenesis. Next we investigate the Akt pathway, using a highly simplified model under different EGF input signal conditions and in the presence of difference sources of variability, in order to determine weather, under these conditions, an information theoretic approach can still be used. We find that such an approach cannot replace the use of mechanistic models to understand the molecular dynamics. Overall, these results are a stepping stone towards understanding the complexities of cellular information processing.
COBE-DMR-normalised Open Inflation, CDM Cosmogony
Creators: name: Gorski, Krzysztof M.
name: Ratra, Bharat
name: Sugiyama, Naoshi
name: Banday, Anthony J.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Fourier analysis on a cut sky of the two-year COBE DMR 53 and 90 GHz sky maps (in galactic coordinates) is used to determine the normalisation of an open inflation model based on the cold dark matter scenario. The normalised model is compared to measures of large-scale structure in the universe. Although the DMR data alone does not provide sufficient discriminative power to prefer a particular value of the mass density parameter, the open model appears to be reasonably consistent with observations when Omega_0 ~ 0.3 - 0.4 and merits further study.
description: uuencoded file containing 6 postscript files (11 pgs text, 4 figures, 1 table)
Additional file 1 of INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): study protocol for a randomized controlled trial
Creators: name: Song, Lili
name: Chen, Chen
name: Chen, Xiaoying
name: Guo, Yijia
name: Liu, Feifeng
name: Lin, Yapeng
name: Billot, Laurent
name: Li, Qiang
name: Liu, Hueiming
name: Si, Lei
name: Ouyang, Menglu
name: Arima, Hisatomi
name: Bath, Philip M.
name: Ford, Gary A.
name: Robinson, Thompson
name: Sandset, Else Charlotte
name: Saver, Jeffrey L.
name: Sprigg, Nikola
name: van der Worp, H. Bart
name: Zhang, Chunfang
name: Yang, Jie
name: Li, Gang
name: Anderson, Craig S.
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Neuroscience
Science Policy
Mental Health

description: Additional file 1.. List of INTERACT4 collaborators
Transport measurements in twisted bilayer graphene: Electron-phonon coupling and Landau level crossing
Creators: name: Chung, Ting-Fung
name: Xu, Yang
name: Chen, Yong P.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We investigate electronic transport in twisted bilayer graphene (tBLG) under variable temperatures ($T$), carrier densities ($n$), and transverse magnetic fields, focusing on samples with small-twist-angles ($θ$). These samples show prominent signatures associated with the van Hove singularities (VHSs) and superlattice-induced mini-gaps (SMGs). Temperature-dependent field effect measurement shows that the difference between temperature-dependent resistivity and residual resistivity, $ρ_{xx}(n,T) - ρ_{0}(n)$, follows $~T^β$ for $n$ between the main Dirac point (DP) and SMG. The evolution of the temperature exponent $β$ with $n$ exhibits a W-shaped dependence, with minima of $β$ ~0.9 near the VHSs and maxima of $β$ ~1.7 toward the SMGs. This W-shaped behavior can be qualitatively understood with a theoretical picture that considers both the Fermi surface smearing near the VHSs and flexural-acoustic phonon scattering. In the quantum Hall regime, we observe only Landau level crossings in the massless Dirac spectrum originating from the main DP but not in the parabolic band near the SMG. Such crossings enable the measurement of an enhanced interlayer dielectric constant, attributed to a reduced Fermi velocity. Moreover, we measure the Fermi velocity, interlayer coupling strength, VHS energy relative to the DP, and gap size of SMG, four important parameters used to describe the peculiar band structure of the small-$θ$ tBLG.
description: 34 pages, 4 figures in the main text and 11 figures in the supplemental material
Characterisation and modulation of the intracellular inflammatory signalling pathways activated during surgery with cardiopulmonary bypass
Creators: name: Nguyen, Bao- Anh Vu
Publisher: name: Imperial College London
Year: 2014

description: Surgery with cardiopulmonary bypass (CPB) is associated with post-operative complications due to systemic inflammation. However, the intracellular signalling pathways that promote inflammation in cardiac surgery with CPB are uncertain. The studies presented in this thesis were designed to illuminate these molecular mechanisms, thereby informing the development of novel anti-inflammatory strategies. This was addressed through a clinical trial to determine the effects of CPB on inflammatory signalling in leukocytes (Chapter 4). In this study, the induction of reactive oxygen species (ROS) and the activation of NF-κB and p38 MAP kinase within leukocytes was compared in patients exposed to miniaturised CPB (mCPB; an optimised form of CPB designed to attenuate systemic inflammatory activation) or conventional CPB (cCPB). Twenty-six patients undergoing surgical revascularisation for advanced coronary artery disease were randomised to undergo surgery with either cCPB or mCPB. Blood samples were collected pre-operatively and at various times after the initiation of CPB and analysed by intracellular staining and flow cytometry for intracellular markers of activation. p38 MAP kinase phosphorylation in granulocytes was enhanced in patients receiving cCPB compared to mCPB (p<0.05). Levels of ROS in lymphocytes were elevated in cCPB compared to mCPB (p<0.01) whereas ROS levels in granulocytes and monocytes were similar between groups. NF-κB phosphorylation in leukocyte sub-sets, leukocyte tissue migration as well as conventional markers of inflammation were comparable between the investigative groups. A porcine model was also established to study the signalling pathways that promote systemic inflammation in response to cardiac surgery with CPB under well-controlled experimental conditions. The influence of sulforaphane, an anti-inflammatory compound derived from green vegetables, on inflammation and injury in response to CPB was also studied. It was observed that pre-treatment of animals with sulforaphane reduced p38 MAP kinase (p<0.05) and NF-κB (p<0.05) phosphorylation in leukocytes exposed to CPB and protected porcine kidneys from exhibiting histological features of early injury. A small clinical study demonstrated biologically significant levels of sulforaphane could be determined in plasma, with lower levels of p38 MAP kinase (p<0.01) and attenuated ROS (p<0.01) in the early stages following consumption. In conclusion, systemic inflammatory responses following CPB were associated with activation of p38 MAP kinase and NF-κB pathways in circulating leukocytes in both porcine and clinical studies. Inflammatory responses to CPB can be reduced by miniaturisation of the CPB circuit and pharmacologically using sulforaphane.
Brownian bridges for late time asymptotics of KPZ fluctuations in finite volume
Creators: name: Mallick, Kirone
name: Prolhac, Sylvain
Publisher: name: arXiv
Year: 2018
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Height fluctuations are studied in the one-dimensional totally asymmetric simple exclusion process with periodic boundaries, with a focus on how late time relaxation towards the non-equilibrium steady state depends on the initial condition. Using a reformulation of the matrix product representation for the dominant eigenstate, the statistics of the height at large scales is expressed, for arbitrary initial conditions, in terms of extremal values of independent standard Brownian bridges. Comparison with earlier exact Bethe ansatz asymptotics leads to explicit conjectures for some conditional probabilities of non-intersecting Brownian bridges with exponentially distributed distances between the endpoints.
description: 43 pages, 5 figures
Classification of singular points in polarization field of CMB and eigenvectors of Stokes matrix
Creators: name: Dolgov, A. D.
name: Doroshkevich, A. G.
name: Novikov, D. I.
name: Novikov, I. D.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Analysis of the singularities of the polarization field of CMB, where polarization is equal to zero, is presented. It is found that the classification of the singular points differs from the usual three types known in the ordinary differential equations. The new statistical properties of polarization field are discussed, and new methods to detect the presence of primordial tensor perturbations are indicated.
description: 7 pages, 1 figures
Additional file 1: of Using behaviour change theory and preliminary testing to develop an implementation intervention to reduce imaging for low back pain
Creators: name: Jenkins, Hazel
name: Moloney, Niamh
name: French, Simon
name: Maher, Chris
name: Dear, Blake
name: Magnussen, John
name: Hancock, Mark
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Selection of appropriate intervention options. Mapping of the Com-B components and the Theoretical Domains Framework to intervention functions and policy categories that meet the APEASE criteria. (DOCX 15 kb)
New approach to the stability and control of reaction networks
Creators: name: Ali, Muhammad
Publisher: name: Imperial College London
Year: 2015

description: A new system-theoretic approach for studying the stability and control of chemical reaction networks (CRNs) is proposed, and analyzed. This has direct application to biological applications where biochemical networks suffer from high uncertainty in the kinetic parameters and exact structure of the rate functions. The proposed approach tackles this issue by presenting "structural" results, i.e. results that extract important qualitative information from the structure alone regardless of the specific form of the kinetics which can be arbitrary monotone kinetics, including Mass-Action. The proposed method is based on introducing a class of Lyapunov functions that we call Piecewise Linear in Rates (PWLR) Lyapunov functions. Several algorithms are proposed for the construction of these functions. Subject to mild technical conditions, the existence of these functions can be used to ensure powerful dynamical and algebraic conditions such as Lyapunov stability, asymptotic stability, global asymptotic stability, persistence, uniqueness of equilibria and exponential contraction. This shows that this class of networks is well-behaved and excludes complicated behaviour such as multi-stability, limit cycles and chaos. The class of PWLR functions is then shown to be a subset of larger class of Robust Lyapunov functions (RLFs), which can be interpreted by shifting the analysis to reaction coordinates. In the new coordinates, the problem transforms into finding a common Lyapunov function for a linear parameter varying system. Consequently, dual forms of the PWLR Lyapunov functions are presented, and the interpretation in terms of the variational dynamics and contraction analysis are given. An other class of Piecewise Quadratic in Rates Lyapunov function is also introduced. Relationship with consensus dynamics are also pointed out. Control laws for the stabilization of the proposed class of networks are provided, and the concept of control Lyapunov function is briefly discussed. Finally, the proposed framework is shown to be widely applicable to biochemical networks.
Rhus toxicodendron Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Sapindales
Anacardiaceae
Rhus
Rhus toxicodendron

description: Rhus toxicodendron, spec. nov.
7. Rhus foliis ternatis: foliolis petiolatis angulatis pubescentibus.
 Rhus foliis ternatis: foliolis petiolatis ovatis acutis pubescentibus: nunc integris, nunc sinuatis. Gron. virg. 149.
 Toxicodendron triphyllum, folio sinuato pubescente. Tournef. inst. 611.
 Arbor trifolia venenata virginiana, folio hirsuto. Raj. hist. 1799.
 Habitat in Virginia , Canada . ♄
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 266, DOI: 10.5281/zenodo.3931989
Comparative efficacy of brigatinib versus ceritinib and alectinib in patients with crizotinib-refractory anaplastic lymphoma kinase-positive non-small cell lung cancer
Creators: name: Reckamp, Karen
name: Lin, Huamao M.
name: Huang, Joice
name: Proskorovsky, Irina
name: Reichmann, William
name: Krotneva, Stanimira
name: Kerstein, David
name: Huang, Hui
name: Lee, Joseph
Publisher: name: Taylor & Francis
Year: 2018
Subjects: Medicine
Cell Biology
Pharmacology
Cancer
Science Policy

description: Objective: Brigatinib, ceritinib, and alectinib are approved to treat crizotinib-refractory anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer (NSCLC), but no trial has compared them head-to-head. A matching-adjusted indirect comparison (MAIC) was conducted to estimate the relative efficacy of these agents in the crizotinib-refractory setting. Methods: MAIC is a propensity score-type method that adjusts for differences in baseline characteristics between trials to estimate relative efficacy. Analyses were based on patient-level data from the ALTA trial for brigatinib and published summary-level trial data from ASCEND-1 and ASCEND-2 for ceritinib and NP28761 and NP28673 for alectinib. Objective response rate (ORR), progression-free survival (PFS), and overall survival (OS) were compared. Results: After matching, all key baseline characteristics were balanced between trials. Compared with ceritinib, brigatinib was associated with longer PFS (ASCEND-1: median 15.7 vs 6.9 months, hazard ratio (HR) [95% confidence interval] = 0.38 [0.26–0.57]; ASCEND-2: median = 18.3 vs 7.2 months, HR = 0.33 [0.20–0.56]) and OS (ASCEND-1: not available; ASCEND-2: median 27.6 vs 14.9 months, HR = 0.33 [0.17–0.63]). Versus alectinib, brigatinib was associated with longer PFS (NP28761: median = 17.6 vs 8.2 months, HR = 0.56 [0.36–0.86]; NP28673: median = 17.6 vs 8.9 months, HR = 0.61 [0.40–0.93]); results for OS were inconclusive (NP28761: median = 27.6 vs 22.7 months, HR = 0.70 [0.42–1.16]; NP28673: median = 27.6 vs 26.0 months, HR = 0.66 [0.39–1.09]). ORR was similar. Conclusion: In crizotinib-refractory ALK + NSCLC patients, relative efficacy estimates suggest brigatinib may have prolonged PFS and OS vs ceritinib and prolonged PFS vs alectinib. Trial registration:ClinicalTrials.gov identifier: NCT02094573. Trial registration:ClinicalTrials.gov identifier: NCT01283516. Trial registration:ClinicalTrials.gov identifier: NCT01685060. Trial registration:ClinicalTrials.gov identifier: NCT01871805. Trial registration:ClinicalTrials.gov identifier: NCT01801111.
Natural explanation for 21cm absorption signals via axion-induced cooling
Creators: name: Houston, Nick
name: Li, Chuang
name: Li, Tianjun
name: Yang, Qiaoli
name: Zhang, Xin
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The EDGES Collaboration has reported an anomalously strong 21cm absorption feature corresponding to the era of first star formation, which may indirectly betray the influence of dark matter during this epoch. We demonstrate that, by virtue of the ability to mediate cooling processes whilst in the condensed phase, a small amount of axion dark matter can explain these observations within the context of standard models of axions and axion-like-particles. The EDGES best-fit result favours an axion-like-particles mass in the (10, 450) meV range, which can be compressed for the QCD axion to (100, 450) meV in the absence of fine tuning. Future experiments and large scale surveys, particularly the International Axion Observatory (IAXO) and EUCLID, should have the capability to directly test this scenario.
description: 5 pages, 2 figures. v3: updated to match version appearing in Phys. Rev. Lett
Additional file 1: of A novel taping therapy for pain after arthroscopic shoulder surgery: study protocol for a randomised controlled pilot trial
Creators: name: Moon, Sun-Young
name: Kim, Jung-Eun
name: O-Jin Kwon
name: Ae-Ran Kim
name: Da-Heui Kim
name: Kim, Jae-Hong
name: Hwang, Hwa
name: Changsop Yang
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Science Policy

description: SPIRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents. (DOC 123 kb)
title: ADCO, Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Cart. 23 (G 127), 310 folios, f. 00212
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00212, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00212, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
The Outer Regions of the Galactic Bulge:I Observations
Creators: name: Ibata, Rodrigo
name: Gilmore, Gerard
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: An observational survey of stars selected from the region of sky in the direction of the Galactic bulge is presented. We discuss the choice of tracer populations for this study. Digitised UK Schmidt plate photometry, calibrated with CCD photometry, is obtained in 18 regions over the bulge. Stars are selected for spectroscopic follow-up from within a carefully chosen colour-magnitude selection window, optimised for efficient detection of bulge K giants. Some 1500 stellar spectra were obtained, with the AAT AUTOFIB facility, giving the largest data set yet obtained in this region of the Galaxy, by a factor of $\approx 10$. We have derived a radial velocity and metallicity for each star, and have quantified the uncertainties in these measurements. Luminosity classification has been derived both by visual classification and using an automated routine based on Principal Component Analysis. There are two basic results from this survey: the discovery of the Sagittarius dwarf galaxy, which is described by Ibata, Gilmore & Irwin (1994,1995), and a study of the Galactic Bulge, which is presented in an accompanying paper (Ibata & Gilmore 1995).
description: MNRAS in press, 13pp, 11figs uuencoded, compressed tarred .ps files
MOESM1 of Identification and characterization of in vivo, in vitro and reactive metabolites of vandetanib using LCâ ESIâ MS/MS
Creators: name: Attwa, Mohamed
name: Kadi, Adnan
name: Darwish, Hany
name: Amer, Sawsan
name: Al-Shakliah, Nasser
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 1: Figure S1. PI chromatograms of molecular ions at m/z 475 of organic extract of control urine sample taken before masitinib dosing showing no peaks at 58.3 min. and 68.6 min. Figure S2. PI chromatograms of molecular ions at m/z 461 of organic extract of control urine sample taken before vandetanib dosing showing no peak at 27.9 min. Figure S3. PI chromatograms of molecular ions at m/z 491 of organic extract of control urine sample taken before vandetanib dosing showing no peak at 56.5 and 67.0 min. Figure S4. Product ion chromatogram of molecular ion peak at m/z 475 showing two peaks: VC491a (56.5 min) and VC491b (67.0 min). Figure S5. PI mass spectrum of molecular ion peak (vandetanib) at m/z 475. Figure S6: PI mass spectrum of molecular ion peak (VC475) at m/z 475. Figure S7. Product ion chromatogram of molecular ion peak at m/z 461 showing one peak: VC461 (57.2 min). Figure S8. PI mass spectrum of molecular ion peak (VC461) at m/z 461. Figure S9. Product ion chromatogram of molecular ion peak at m/z 491 showing two peaks: VC491a (56.5 min) and VC491b (67.0 min). Figure S10. PI mass spectrum of molecular ion peak (VC491a) at m/z 491. Figure S11. PI mass spectrum of molecular ion peak (VC491b) at m/z 491.
Additional file 1: of Noncontrast magnetic resonance imaging versus ultrasonography for hepatocellular carcinoma surveillance (MIRACLE-HCC): study protocol for a prospective randomized trial
Creators: name: Chansik An
name: Kim, Do
name: Choi, Jin-Young
name: Han, Kwang
name: Roh, Yun
name: Myeong-Jin Kim
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Explanation for study participants (Translated version). This document describes the purposes, procedures, benefits, risks, inconveniences, and precautions of this study. All the patients read this document and fully understood the explanation of the study, before they decided whether or not they would agree to participate in the study. This document is a translated version from the original one written in Korean. (DOCX 22 kb)
The Outer Regions of the Galactic Bulge:II Analysis
Creators: name: Ibata, Rodrigo
name: Gilmore, Gerard
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We analyse velocity, chemical abundance and spatial distribution data for some 1500 K- and M- giants in the Galactic Bulge. The bulge has a well-determined linear rotation curve over the range $\rm 700pc \le R \le 3500pc$ with amplitude ${\rm \sim 25 km s^{-1} kpc^{-1}}$. The oblate isotropic bulge model of Kent (1992) is in reasonable agreement with our data. We do not find a significant requirement for asymmetry or a bar. The metallicity distribution of K giants in a subset of our fields, using the Mg$b$ feature, has mean ${\rm [Fe/H] \approx -0.3}$ with no variation. That is, there is no detectable abundance gradient in the Galactic bulge over the galactocentric range $\rm 500pc \le R_{GC} \le 3500pc$. We derive the distribution function of specific angular momentum for the bulge from our data, and compare it with determinations for the halo, the thick disk and the thin disk from Wyse & Gilmore (1992). We confirm that the bulge and the halo have angular momentum distributions which are indistinguishable, as do the thick disk and the thin disk. The bulge-halo distribution is however very different from the thick disk-thin disk distribution. This is perhaps the strongest available clue to the evolutionary relationships between different Galactic structural components.
description: MNRAS in press, 23pp incl figures, uuencoded, tarred, compressed
Unequal-mass galaxy mergers and the creation of cluster S0 galaxies
Creators: name: Bekki, Kenji
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: It is a longstanding and remarkable problem when and how red S0 galaxies were formed in clusters of galaxies. We here propose that the major mechanism for the S0 creation is galaxy merging between two spirals with unequal mass. Our numerical simulations demonstrate that galaxy merging exhausts a large amount of interstellar medium of two gas-rich spirals owing to the moderately enhanced star formation, and subsequently transforms the two into one gas-poor S0 galaxy with structure and kinematics strikingly similar to the observed ones. This secondary S0 formation with enhanced star formation explains a smaller fraction of S0 population recently observed in some distant clusters of galaxies. Unequal-mass galaxy mergers thus provide an evolutionary link between a larger number of blue spirals observed in intermediate redshift clusters and red S0s prevalent in the present-day ones.
description: 14 pages 3 figures (ps file), ApJL in press
A Luminous Companion to SGR 1806-20
Creators: name: van Kerkwijk, M. H.
name: Kulkarni, S. R.
name: Matthews, K.
name: Neugebauer, G.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have obtained infrared spectra of the star suggested to be the counterpart of the soft gamma-ray repeater (SGR) 1806-20. We found strong emission lines similar to those seen in the spectra of the rare Luminous Blue Variables and B[e] stars. A He I absorption line is also seen, from which we infer a spectral type O9--B2. This classification, in combination with the minimum distance of $\simgt6$ kpc inferred from its extinction, makes the star one of the most luminous in the Galaxy. We infer that it is a companion to SGR 1806-20, and suggest that the presence of a companion is somehow related to the SGR phenomenon.
description: 5 pages, AASTEX text+table and 2 PostScript figures (needs LaTeX style files aaspptwo.sty, epsf.sty and rotate.sty). In case of problems, contact mhvk@astro.caltech.edu. Postscript file of complete article available on request. (Replaced because first version had one wrong reference in it)
Additional file 3 of INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): study protocol for a randomized controlled trial
Creators: name: Song, Lili
name: Chen, Chen
name: Chen, Xiaoying
name: Guo, Yijia
name: Liu, Feifeng
name: Lin, Yapeng
name: Billot, Laurent
name: Li, Qiang
name: Liu, Hueiming
name: Si, Lei
name: Ouyang, Menglu
name: Arima, Hisatomi
name: Bath, Philip M.
name: Ford, Gary A.
name: Robinson, Thompson
name: Sandset, Else Charlotte
name: Saver, Jeffrey L.
name: Sprigg, Nikola
name: van der Worp, H. Bart
name: Zhang, Chunfang
name: Yang, Jie
name: Li, Gang
name: Anderson, Craig S.
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Neuroscience
Science Policy
Mental Health

description: Additional file 3.. TSC Charter
Ultraviolet-Optical observations of the Seyfert 2 Galaxies NGC 7130, NGC 5135 and IC 3639: Implications for the Starburst-AGN Connection
Creators: name: Delgado, Rosa M. Gonzalez
name: Heckman, Timothy
name: Leitherer, Claus
name: Meurer, Gerhardt
name: Krolik, Julian
name: Wilson, Andrew
name: Kinney, Anne
name: Koratkar, Anuradha
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present and discuss HST (WFPC2 and FOC) images and UV GHRS spectra plus ground-based near UV through to near IR spectra of three Seyfert 2 nuclei (NGC 7130, NGC 5135 and IC 3639). These galaxies, together to Mrk 477, were selected from a bigger sample that comprises the 20 brightest Seyfert 2 nuclei, with the goal to study the origin of the UV-optical-near IR featureless continuum in Seyfert 2 nuclei. These four galaxies have bolometric luminosities, as computed with the four IRAS bands, of 10^11 Lsol. They are close enough to be resolved with HST the nuclear zone. This makes these Seyfert 2 galaxies benchmarks to study the Starburst-AGN connection in more distant galaxies. The data provide direct evidence of the existence of a central nuclear starburst that dominates the UV light, and that seem to be responsible for the origin of the so called featureless continuum. These starbursts are dusty and compact. They have sizes (from less than 100 pc to a few hundred pc) much smaller and closer to the nucleus than that seen in the prototype Seyfert 2 galaxy NGC 1068. The bolometric luminosity of these starbursts is similar to the estimated bolometric luminosities of their obscured Seyfert 1 nuclei, and thus they contribute in the same amount to the overall energetics of these galaxies.
description: to be published in ApJ 505, September issue. The figures are in a tar files at: http://www.iaa.es/~rosa/Seyferts
Genetic manipulation of fermentative metabolism in Chlamydomonas reinhardtii
Creators: name: Haji Taha, Hussein
Publisher: name: Imperial College London
Year: 2015

description: Photobiological hydrogen production by green algae, such as Chlamydomonas reinhardtii is an attractive approach to generate renewable energy, but is currently not economically viable. It has been suggested that hydrogen yields could potentially be improved by eliminating or down-regulating competing fermentative pathways. However, at present fermentative metabolism is not completely understood in C. reinhardtii, such as the nature of the ill-defined D-lactate dehydrogenase (D-LDH) activity responsible for the production of D-lactate. To characterise the D-LDH activity, a bioinformatics analysis identified a candidate nucleus-encoded D-LDH in the C. reinhardtii genome (Phytozome v9.1 ID: Cre07.g324550), which was predicted to be localised to the chloroplast. The putative protein without its predicted chloroplast transit peptide was overexpressed in Escherichia coli as a C-terminal His6-tagged protein to confirm its function and assess its structure. Enzyme assays confirmed that the protein was an NAD+-dependent D-LDH, favouring the reduction of pyruvate to D-lactate with an estimated Km value of 1.85 ± 0.05 mM and kcat value of 415 ± 18 s-1. Size-exclusion chromatography suggests the holoenzyme was tetrameric with a molecular mass of about 202 kDa. Artificial microRNA technology was used to reduce the amount of D-LDH protein to less than 20% of WT levels. D-lactate was still produced in the mutant either from residual D-LDH activity or from other routes such as from methylglyoxal. Both NMR and HPLC confirmed that the knockdown did not have any substantial impact on dark anaerobic metabolite production except in slightly increasing the pyruvate levels. Additionally, the knockdown did not improve hydrogen yields under sulphur-deprived conditions. To assess the impact of eliminating fermentative pathways on metabolism, a series of mutants was isolated through cell mating, targeting the enzymes D-LDH, pyruvate decarboxylase (PDC3), pyruvate formate lyase (PFL1) and a bifunctional acetaldehyde/alcohol dehydrogenase (ADH1). Dark anaerobic metabolite production in the quadruple mutant confirmed the re-routing of metabolic flux from ethanol and formate towards glycerol and D-lactate. There was also a reduced flux towards acetate production. Pyruvate and glucose levels were found to be elevated in this mutant. Gas chromatography analysis suggested that downregulation of the fermentative pathways did not improve hydrogen production under sulphur-deprived conditions, in part because of reduced cell viability. These mutants are promising tools for future studies probing the metabolism of C. reinhardtii.
Reminiscences of Robert B. Luckey 1969
Publisher: name: Columbia University
Year: 2019
Subjects: Veterans
World War, 1939-1945--Naval operations, American
Military education
Amphibious warfare

description: Education, University of Maryland, 1923-27; expeditionary duty, Nicaragua, 1929; early assignments, artillery training; United States Embassy Guard, Peking, 1936-38; aide to General James Breckinridge, 1938-39; World War II: Guadalcanal, Cape Gloucester, and Okinawa operations, occupation of Tsingtao; United States Marine Corps in interwar period; postwar assignments: Marine Barracks, Washington, D.C., 1949-51; United States Marine Corps Schools, Quantico; Hogaboom Board, 1953-54; Fleet Marine Force, Atlantic, 1954-55; amphibious warfare operations; United States Marine Corps Recruit Depots, Parris Island, 1957-59; 3d Marine Division, 1959-1960; Far Eastern situation; Camp Lejeune, 1960-61; Commanding General, Fleet Marine Force, Atlantic, 1961-63; contingency planning.
Toxicodendron pubescens Mill.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Sapindales
Anacardiaceae
Toxicodendron
Toxicodendron pubescens

description: Rhus toxicodendron Linnaeus, Species Plantarum 1: 266. 1753.
"Habitat in Virginia, Canada." RCN: 2121.
Lectotype (Fernald in Rhodora 43: 589, pl. 685, f. 1, 2. 1941): Herb. Linn. No. 378.16, left specimen (LINN).
Current name: Toxicodendron pubescens Mill. (Anacardiaceae).
Note: See discussion by Gillis (in Rhodora 73: 402, f. 52. 1971).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 795, DOI: 10.5281/zenodo.291971
Reminiscences of Robert Bergland, 1982
Publisher: name: Columbia University
Year: 2021
Subjects: Cabinet officers--United States
Legislators--United States
Agriculture--Economic aspects
Agriculture and state
Green Revolution

description: Congressional tenure, 1970-77: creation of Commodities Futures Trading Commission, Soviet grain sales, Organization of Petroleum Exporting Countries and the oil embargo, National Aeronautics and Space Administration, surplus dumping programs; Secretary of Agriculture, 1977-81; intelligence gathering, Food Stamp program, Farmer-owned Grain Reserve Program, budgeting prodecures, soil erosion control, American Agricultural Movement, 1978-79, Food for Peace Program (Public Law 480), embargo on Soviet grain sales, 1979-80, issuance of nutritional guidelines, school lunch program, pest and predator control, loan and insurance programs; Presidential campaign, 1980; Equal Opportunity; views on: farm income and price support plans, crop subsidies, large vs family farms, farm workers, market orders, foreign and minority farm ownership, the Green Revolution, foreign agriculture, organic farming; impressions of Jimmy Carter, other officials
MOESM1 of Proteomic profiling of the plasma of Gambian children with cerebral malaria
Creators: name: Ehab Moussa
name: Honglei Huang
name: ThĂŠzĂŠnas, Marie
name: Fischer, Roman
name: Abhinay Ramaprasad
name: Fatou Sisay-Joof
name: Muminatou Jallow
name: Arnab Pain
name: Kwiatkowski, Dominic
name: Kessler, Benedikt
name: Climent Casals-Pascual
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. List of differentially expressed proteins in fatal CM cases as measured by LC-MS/MS analysis.
Globular Clusters with Tidal Tails: Deep Two-Color Star Counts
Creators: name: Grillmair, C. J.
name: Freeman, K. C.
name: Irwin, M.
name: Quinn, P. J.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We examine the outer structure of 12 Galactic globular clusters using star-count analyses. Deep, two-color, photographic photometry is used to select and count stars with colors and magnitudes consistent with cluster-specific, color-magnitude sequences. The resulting reduction in the number of contaminating foreground stars allows us to push the star counts to significantly lower surface densities than has previously been possible. We find that most of our sample clusters show extra-tidal wings in their surface density profiles. The form of the surface density profiles is consistent with recent numerical studies of the tidal stripping of globular clusters. Two-dimensional surface density maps for several clusters are consistent with the expected appearance of tidal tails, with allowance for the effects of orbit shape, orbital phase, and orientation of our line of sight. We identify the extra-tidal material with stars which are still in the process of being removed from the clusters. The extra-tidal stars effectively limit the accuracy to which we can resolve the ``tidal'' radii of globular clusters. However, by tracing the orbital paths of their parent clusters, these stars may also facilitate a renewed attack on the problem of determining globular cluster orbits and the shape of the Galactic potential field.
description: to appear in AJ, 29 pgs + 17 tables (Latex, AASTEX macros) + 30 pages of uuencoded, gzipped postscript figures. Figures 1 and 13 available on request from Grillmair (carl@sundown.ucsc.edu).
Reminiscences of Robert Bruce Raup, 1963
Publisher: name: Columbia University
Year: 2021
Subjects: Educators
Education--Aims and objectives
Education--Experimental methods
Education--Vocational guidance

description: Education and early teaching experiences in the Middle West; Teachers College, 1920-1954; SOCIAL FRONTIERS; social and philosophical foundations of education; relationship of Teachers College and Columbia University. Impressions of John Dewey, W.H. Kilpatrick, E.L. Thorndike, James Russell and William Russell, Harold Rugg, and others
Large eddy simulation of deflagration to detonation transition
Creators: name: Yu, Shaoxi
Publisher: name: Imperial College London
Year: 2015

description: Deflagration to detonation transition (DDT) is a very important research project for both national defense and energy industry. It is the process where a subsonic deflagration transits into a supersonic detonation, which generates shock waves. In the past years, the simulations of DDT were limited in a small domain, usually sev- eral cubic centimeters. If we want to simulate it in a larger space without improving the numerical method, we need to use the more powerful computer. When the computing resources are limited, we must improve the numerical method to achieve the big-domain simulating. There are two technical paths, one is the adaptive mesh refinement and the other is the large eddy simulation. Both of them are difficult to realize. In this project, we focus on the usage of the LES method for simulating DDT. The main challenge in this work is to develop a reliable model. In this research, a new approach for LES modelling was developed. It is a fully compressible variant of the artificial thickened flame model, which adopts the opt- ing functions on the reference flame thickness. This method ensures that the flame is not over-thickened in deflagration or detonation. To control the options on the flame thickness, a detonation sensor is utilized during the computing.
Photoinduced valley and electron-hole symmetry breaking in $ α$-$T_3$ lattice: The role of a variable Berry phase
Creators: name: Dey, Bashab
name: Ghosh, Tarun Kanti
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We consider $α$-$T_3$ lattice illuminated by intense circularly polarized radiation in terahertz regime. We present quasienergy band structure, time-averaged energy spectrum and time-averaged density of states of $α$-$T_3$ lattice by solving the Floquet Hamiltonian numerically. We obtain exact analytical expressions of the quasienergies at the Dirac points for all values of $α$ and field strength. We find that the quasienergy band gaps at the Dirac point decrease with increase of $α$. Approximate forms of quasienergy and band gaps at single and multi-photon resonant points are derived using rotating wave approximation. The expressions reveal a stark dependence of quasienergy on the Berry phase of the charge carrier. The quasi energy flat band remains unaltered in presence of radiation for dice lattice ($α=1$). However, it acquires a dispersion in and around the Dirac and even-photon resonant points when $0