cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Comparative Analysis of Data Preprocessing Methods, Feature Selection Techniques and Machine Learning Models for Improved Classification and Regression Performance on Imbalanced Genetic Data
Creators: name: Kaur, Arshmeet
name: Sarmadi, Morteza
Publisher: name: arXiv
Year: 2024
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Biological sciences
subject: FOS: Computer and information sciences

description: Rapid advancements in genome sequencing have led to the collection of vast amounts of genomics data. Researchers may be interested in using machine learning models on such data to predict the pathogenicity or clinical significance of a genetic mutation. However, many genetic datasets contain imbalanced target variables that pose challenges to machine learning models: observations are skewed/imbalanced in regression tasks or class-imbalanced in classification tasks. Genetic datasets are also often high-cardinal and contain skewed predictor variables, which poses further challenges. We aimed to investigate the effects of data preprocessing, feature selection techniques, and model selection on the performance of models trained on these datasets. We measured performance with 5-fold cross-validation and compared averaged r-squared and accuracy metrics across different combinations of techniques. We found that outliers/skew in predictor or target variables did not pose a challenge to regression models. We also found that class-imbalanced target variables and skewed predictors had little to no impact on classification performance. Random forest was the best model to use for imbalanced regression tasks. While our study uses a genetic dataset as an example of a real-world application, our findings can be generalized to any similar datasets.
description: Ann. Data. Sci. (2024)
Colonial Gothic
Creators: name: Steer, Philip
Publisher: name: Oxford University Press
Year: 2016
Subjects: subject: Caribbean literature--Colonial influence
subject: Canadian literature
subject: Australian literature
subject: Gothic fiction (Literary genre)
subject: New Zealand literature

description: This chapter examines the colonial Gothic novel. Pervasive in the literatures of Canada, Australia, New Zealand, and the Caribbean, the colonial Gothic is more appropriately described as a mode rather than a discrete genre, and its representational possibilities have been shaped by three broad phases of generic transformation and cross-fertilization within the Anglophone novel during the period in question. While the popularity of the Gothic novel peaked in the 1790s with the romances of Ann Radcliffe, its translation into British colonial contexts was enabled in the early decades of the nineteenth century through the hugely successful historical novels of Walter Scott and James Fenimore Cooper. A resurgence of Gothic tropes and themes occurred in the wake of the British romance revival of the 1880s. Finally, twentieth-century examples of the colonial Gothic increasingly occur within a literary terrain transformed by the rise of modernism and growing attempts to produce distinct national traditions of realist writing.
sj-doc-1-joo-10.1177_14653125211027266 – Supplemental material for Predictability of rotational tooth movement with orthodontic aligners comparing software-based and achieved data: A systematic review and meta-analysis of observational studies
Creators: name: Koletsi, Despina
name: Iliadi, Anna
name: Eliades, Theodore
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-doc-1-joo-10.1177_14653125211027266 for Predictability of rotational tooth movement with orthodontic aligners comparing software-based and achieved data: A systematic review and meta-analysis of observational studies by Despina Koletsi, Anna Iliadi and Theodore Eliades in Journal of Orthodontics
sj-pdf-1-psx-10.1177_00323217211020243 – Supplemental material for Media Freedom and the Escalation of State Violence
Creators: name: Carey, Sabine C
name: González, Belén
name: Mitchell, Neil J
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-pdf-1-psx-10.1177_00323217211020243 for Media Freedom and the Escalation of State Violence by Sabine C Carey, Belén González and Neil J Mitchell in Political Studies
Fractional positional jumps in stochastic systems with tilted periodic double-well potentials
Creators: name: Žonda, Martin
name: Belzig, Wolfgang
name: Goldobin, Edward
name: Novotný, Tomáš
Publisher: name: arXiv
Year: 2024
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We present a theoretical investigation of the stochastic dynamics of a damped particle in a tilted periodic potential with a double well per period. By applying the matrix continued fraction technique to the Fokker-Planck equation in conjunction with the full counting statistics and master equation approaches, we determine the rates of specific processes contributing to the system's overall dynamics. At low temperatures, the system can exhibit one running state and two distinct locked metastable states. We focus primarily on two aspects: the dynamics of positional jumps, which are rare thermally induced particle jumps over potential maxima, and their impact on the overall velocity noise; and the retrapping process, involving the transition from the running to the locked metastable states. We demonstrate the existence of fractional (in units of $2π$) positional slips that differ qualitatively from conventional $2π$ jumps observed in single-well systems. Fractional positional slips significantly influence the system dynamics even in regimes dominated by dichotomous-like switching between running and locked states. Furthermore, we introduce a simple master equation approach that proves effective in analyzing various stages of the retrapping process. Interestingly, our analysis shows that even for a system featuring a well-developed double-well periodic potential, there exists a broad parameter range where the stochastic dynamics can be accurately described by an effective single-well periodic model. The techniques introduced here allow for valuable insights into the complex behavior of the system, offering avenues for understanding and controlling its steady-state and transient dynamics, which go beyond or can be complementary to direct stochastic simulations.
description: 13 pages, 9 figures
मणिपुर हिंसा: खनिज, तेल और अफीम
Creators: name: Ranjan, Pramod
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: India--Manipur
subject: Ethnic conflict
subject: Genocide

description: मणिपुर में 2023 में शुरु हुई हिंसा के बारे में स्थानीय स्तर जो चर्चाएं थीं, उनमें तीन चीजों की मुख्य भूमिका बताई जा रही है। इनमें पहला है मणिपुर की पहाड़ियों में मौजूद बेशकीमती खनिज, दूसरा है पाम तेल के वृक्ष की खेती का मसला, और तीसरा है अफीम का अवैध कारोबार।   इस लेख में इनके पीछे के विभिन्न कारकों पर प्रकाश डाला गया है।
Quantum robustness of the toric code in a parallel field on the honeycomb and triangular lattice
Creators: name: Kott, V.
name: Mühlhauser, M.
name: Koziol, J. A.
name: Schmidt, K. P.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the quantum robustness of the topological order in the toric code on the honeycomb lattice in the presence of a uniform parallel field. For a field in $z$-direction, the low-energy physics is in the flux-free sector and can be mapped to the transverse-field Ising model on the honeycomb lattice. One finds a second-order quantum phase transition in the 3D Ising$^\star$ universality class for both signs of the field. The same is true for a postive field in $x$-direction where an analogue mapping in the charge-free sector yields a ferromagnetic transverse-field Ising model on the triangular lattice and the phase transition is still 3D Ising$^\star$. In contrast, for negative $x$-field, the charge-free sector is mapped to the highly frustrated antiferromagnetic transverse-field Ising model on the triangular lattice which is known to host a quantum phase transition in the 3D XY$^\star$ universality class. Further, the charge-free sector does not always contain the low-energy physics for negative $x$-fields and a first-order phase transition to the polarized phase in the charge-full sector takes place at larger negative field values. We quantify the location of this transition by comparing quantum Monte Carlo simulations and high-field series expansions. The full extension of the topological phase in the presence of $x$- and $z$-fields is determined by perturbative linked-cluster expansions using a full graph decomposition. Extrapolating the high-order series of the charge and the flux gap allows to estimate critical exponents of the gap closing. This analysis indicates that the topological order breaks down by critical lines of 3D Ising$^\star$ and 3D XY$^\star$ type with interesting potential multi-critical crossing points. All findings for the toric code on the honeycomb lattice can be transferred exactly to the toric code on the triangular lattice.
description: 26 pages, 8 figures
“I Just Told Them Like It Was”: Performance and History at Colonial Williamsburg
Creators: name: Gentry, Philip
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Americana (Music)
subject: Public history
subject: African Americans--Music
subject: Herrmann, Bernard, 1911-1975
subject: Lomax, Alan, 1915-2002
subject: Sea Island Singers
subject: Virginia--Williamsburg--Colonial Williamsburg

description: Since its organization in the mid-twentieth century, Colonial Williamsburg (CW) has been an important site for the consolidation of powerful narratives of American exceptionalism, patriotism, and the so-called consensus history of the American Revolution. This article looks at the role that music and performance has played in this historiography, taking as its primary texts two films produced by CW: The Story of a Patriot (1957) and The Music of Williamsburg (1960). With musical contributions by Bernard Herrmann and Alan Lomax, respectively, these films offer an opportunity to analyze the relationship between history and politics in the early Cold War era. Although The Story of a Patriot reflects a static and essentially conservative portrayal of American exceptionalism, the more liberal inclusiveness of The Music of Williamsburg showcases the fraught power dynamics of attempting to showcase historical Black music making in a patriotic context.
title: Système d’indicateurs sur les addictions : Chiffres-clé sur la consommation de substances psychoactives chez les jeunes de 11 à 24 ans dans le canton de Vaud
Creators: name: Henry, Valérie
name: Pin, Stéphanie
Publisher: name: Institut universitaire de médecine sociale et préventive (IUMSP)
Year: 2018
Subjects: Addictions

description: Le Département de la santé et de l’action sociale (DSAS) du canton de Vaud est chargé de la mise en oeuvre de la politique de prévention et de lutte contre les méfaits des addictions. Afin d’assurer le pilotage de cette politique, le DSAS souhaite disposer d’indicateurs fiables lui permettant d’évaluer les besoins, de planifier l’offre de prise en charge médico-sociale et d’évaluer les effets des projets et programmes soutenus financièrement.
description: Le monitorage porte sur cinq thèmes : (1) la situation épidémiologique du canton de Vaud en matière de consommation de substances et de comportements addictifs ; (2) le repérage et les interventions précoces dans la population jeune ; (3) la prise en charge médico-sociale ; (4) la réduction des risques, et (5) la répression et la régulation du marché.
description: Ce document propose une synthèse des indicateurs retenus concernant la situation épidémiologique du canton de Vaud en matière de consommation d’alcool, de tabac et de cannabis chez les jeunes de 11 à 24 ans.
Additional file 1 of Repeatability of deuterium metabolic imaging of healthy volunteers at 3 T
Creators: name: Bøgh, Nikolaj
name: Vaeggemose, Michael
name: Schulte, Rolf F.
name: Hansen, Esben S S
name: Laustsen, Christoffer
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Mental Health

description: Additional file 1: Figure S1. Illustration of the DMI processing pipeline. The spectrum is a single voxel located in the cortex of the middle of the brain. Partial volume correction was performed using an iterative Lucy-Richardson method. The bias field was estimated and corrected for with multiplicative intrinsic component. Figure S2. Blood glucose over time after intake of [6,6-2H2]glucose (a) and the correlation between the blood glucose at 60 minutes (the peak) and the DMI whole-brain glucose signal at 120 minutes (b). Figure S3. Transmit profile of the employed 1H/2H coil. The transmit field on deuterium was measured across a saline phantom using a double-angle experiment (a). The field varied with ± 7% (b). Figure S4. Montage of raw DMI data from a single volunteer at 120 minutes after oral [6,6-2H2]glucose. The root-mean square of the 2H-spectrum is presented, the data were zero filled twice in all directions. Figure S5. Bland-Altman plots of repeatability of DMI at 30, 75, and 120 minutes after oral ingestion of [6,6-2H2]glucose. Glx = glutamine+glutamate. Figure S6. Correlation plots of repeatability of DMI at 30, 75, and 120 minutes after oral ingestion of [6,6-2H2]glucose. Glx = glutamine+glutamate.
Muslim Libraries, Academic Institutions, and Intellectual and Scientific Progress: 750 and 1258 CE (133 – 656 AH): Baghdad’s House of Wisdom and Cairo’s House of Science
Creators: name: Akyildiz, Sevket
Publisher: name: Humanities Commons
Year: 2004
Subjects: subject: History
subject: Islamic Empire
subject: Public libraries
subject: Education

description: COPYRIGHT CC BY-NC-ND SEVKET AKYILDIZ SUMMER 2021 Sevket Akyildiz. Muslim culture had started with a single book - the Qur’an, which was revealed to the Prophet Muhammad (b.570—d.632 CE) between the years 610 and 632 CE. Yet, within three hundred years, Islamic civilisation had some of the largest and best-stocked libraries in the known world.
sj-docx-3-bji-10.1177_17571774211012463 – Supplemental material for Development and pilot evaluation of an educational programme on infection prevention and antibiotics with English and Scottish youth groups, informed by COM-B
Creators: name: Hayes, Catherine V
name: Eley, Charlotte V
name: Ashiru-Oredope, Diane
name: Hann, Magda
name: McNulty, Cliodna AM
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111099 Nursing not elsewhere classified
subject: 111799 Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-docx-3-bji-10.1177_17571774211012463 for Development and pilot evaluation of an educational programme on infection prevention and antibiotics with English and Scottish youth groups, informed by COM-B by Catherine V Hayes, Charlotte V Eley, Diane Ashiru-Oredope, Magda Hann and Cliodna AM McNulty in Journal of Infection Prevention
sj-docx-1-nms-10.1177_14614448211027171 – Supplemental material for Exploring the learning potential of online gaming communities: An application of the Game Communities of Inquiry Scale
Creators: name: Gandolfi, Enrico
name: Ferdig, Richard E
name: Soyturk, Ilker
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, sj-docx-1-nms-10.1177_14614448211027171 for Exploring the learning potential of online gaming communities: An application of the Game Communities of Inquiry Scale by Enrico Gandolfi, Richard E Ferdig and Ilker Soyturk in New Media & Society
sj-docx-2-nms-10.1177_14614448211027171 – Supplemental material for Exploring the learning potential of online gaming communities: An application of the Game Communities of Inquiry Scale
Creators: name: Gandolfi, Enrico
name: Ferdig, Richard E
name: Soyturk, Ilker
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, sj-docx-2-nms-10.1177_14614448211027171 for Exploring the learning potential of online gaming communities: An application of the Game Communities of Inquiry Scale by Enrico Gandolfi, Richard E Ferdig and Ilker Soyturk in New Media & Society
From language to algorithm: trans and non‑binary identities in research on facial and gender recognition
Creators: name: Laila, Ferreira
name: Mary Ann S., Saunders
name: Thieme, Katja
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Human-computer interaction
subject: Academic writing
subject: Computer science
subject: Gender identity
subject: Rhetoric
subject: Machine learning
subject: Artificial intelligence

description: We assess the state of thinking about gender identities in computer vision through an analysis of how research papers in gender and facial recognition are designed, what claims they make about trans and non-binary people, what values they espouse, and what they describe as ongoing challenges for the field. In our corpus of 50 research papers, the seven papers that consider trans and non-binary identities use questionable assumptions about medicalization as a measure of transness, about gender transition as a linear and bounded process, and about the concept of gender deception. Otherwise, non-normative gender identities are absent and their consideration is in fact hindered by prevailing research values, particularly deeply embedded ones such as performance and accuracy. We point out how the use of shared datasets calcifies binary conceptions of gender. In the way that the field of computer vision conceives of ongoing challenges for its research, it does not yet face questions that trans and non-binary user experiences pose and often falls back on biologically essentialist notions of sex classification. We make two recommendations: that computer vision researchers undertake interdisciplinary work with researchers who study gender as a socio-cultural phenomenon, and that journal editors and conference organizers do the same in peer review and conference acceptance processes.
sj-pdf-1-nms-10.1177_14614448211026059 – Supplemental material for Remix’s retreat? Content moderation, copyright law and mashup music
Creators: name: Brøvig-Hanssen, Ragnhild
name: Jones, Ellis
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, sj-pdf-1-nms-10.1177_14614448211026059 for Remix’s retreat? Content moderation, copyright law and mashup music by Ragnhild Brøvig-Hanssen and Ellis Jones in New Media & Society
Selbstmedikation mit Over-the-Counter-(OTC-)Präparaten in Deutschland
Creators: name: Beitz, Ramona
name: Dören, Martina
name: Knopf, Hildtraud
name: Melchert, Hans-Ulrich
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2004
Subjects: subject: Selbstmedikation
subject: Deutschland
subject: OTC-Arzneimittel
subject: Pharmakoepidemiologie
subject: Germany
subject: Self-medication
subject: OTC drugs
subject: Pharmacoepidemiology
subject: 610 Medizin

description: Die Selbstmedikation mit OTC-Präparaten gewinnt in Deutschland und international zunehmend an Bedeutung. In dieser Arbeit werden Prävalenz und Determinanten der Selbstmedikation mit OTC-Präparaten in einer repräsentativen Stichprobe der deutschen erwachsenen Wohnbevölkerung zwischen 18 und 79 Jahren untersucht. Zu diesem Zweck wurden im Arzneimittelsurvey als Teil des repräsentativen Bundes-Gesundheitssurveys (1998) 7.099 Teilnehmer ausführlich über ihre Arzneimittelanwendung während der letzten 7 Tage interviewt. Vollständige Informationen dazu liegen von 3.393 Männern und 3.594 Frauen vor. 17,6% der Männer und 10,8% der Frauen wenden ausschließlich selbst medizierte OTC-Arzneimittel an, während 12,3% bzw. 29,3% zusätzlich zu den OTC-Arzneimitteln ärztlich verordnete Arzneimittel anwenden. Determinanten der Selbstmedikation mit OTC-Arzneimitteln sind u. a. das Geschlecht, das Alter, der sozioökonomische Status und die Gemeindegröße. Am häufigsten werden Vitamine, Mineralstoffe und Analgetika eingesetzt. Die häufigste Selbstangabe zur Indikation der OTC-Medikation ist Prävention. Die Selbstmedikation mit OTC-Präparaten ist für Männer und Frauen in Deutschland von großer Bedeutung. Etliche Faktoren außerhalb des unmittelbar medizinischen Bereiches erscheinen hier wichtig. Der Aspekt eines gestiegenen Gesundheitsbewusstseins scheint für die Selbstmedikation relevant zu sein.
description: Self-medication with OTC drugs is attracting attention in developed countries. This study examines prevalence and determinants of OTC drug use in a representative sample of German adults aged 18–79 years. A total of 7099 participants of the Drug Utilisation Survey were interviewed regarding drug use including OTC use within the last 7 days prior to the interview. This survey is a part of the representative German National Health Interview and Examination Survey 1998. Complete information is available from 3393 men and 3594 women: 17.6% of men and 10.8% of women use self-medicated OTC drugs exclusively, whereas 12.3% and 29.3%, respectively, use OTC drugs in addition to prescribed drugs. Besides sex, factors such as age, socioeconomic status and community size determine self-medication with OTC drugs. The most commonly used self-medicated OTC drugs are vitamins, minerals and analgesics. The most commonly reported indication for self-medication with OTC drugs is prevention. Beside prescribed medication, self-medication with OTC drugs is an important part of drug usage for men and women in Germany. Health consciousness appears to be a significant factor to explain the prevalence OTC drug use.
Expressive Freedom and Ethical Responsibility at Canadian Universities
Creators: name: Thieme, Katja
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Academic freedom
subject: Freedom of expression
subject: Transgender people
subject: Universities and colleges

description: This article reviews recent government incursions on questions of free speech at universities and colleges in Ontario and Alberta and presents the challenge they pose to university autonomy. Inherent in university autonomy is the possibility—or the obligation—that universities make decisions based on ethical responsibilities that can extend beyond the limits of current law. As a case study of university autonomy in matters of expressive freedom, I highlight events at the University of British Columbia, which leads me to a discussion of how questions of ethical responsibility have been raised particularly in relation to the speech protection of transgender members of the university. A central issue is the need for universities to adjudicate when free speech rights meet related responsibilities with which they can conflict. I detail how, for instance, the invitation of some anti-trans speakers can pose such a conflict and should lead university communities to consider adjusting their responses in extreme cases so as to be able to more autonomously regulate hateful speech beyond applicable law.
$n$-point functions in Conformal Quantum Mechanics: A Momentum Space Odyssey
Creators: name: S, Dhruva K.
name: Mazumdar, Deep
name: Yadav, Shivang
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In this paper, we study the implications of conformal invariance in momentum space for correlation functions in quantum mechanics. We find that three point functions of arbitrary operators can be written in terms of the $_2 F_1$ hypergeometric function. We then show that generic four-point functions can be expressed in terms of Appell's generalized hypergeometric function $F_2$ with one undetermined parameter that plays the role of the conformal cross ratio in momentum space. We also construct momentum space conformal partial waves, which we compare with the Appell $F_2$ representation. We test our expressions against free theory and DFF model correlators, finding an exact agreement. We then analyze five, six, and all higher point functions. We find, quite remarkably, that $n$-point functions can be expressed in terms of the Lauricella generalized hypergeometric function, $E_A$, with $n-3$ undetermined parameters, which is in one-to-one correspondence with the number of conformal cross ratios. This analysis provides the first instance of a closed form for generic momentum space conformal correlators in contrast to the situation in higher dimensions. Further, we show that the existence of multiple solutions to the momentum space can be attributed to the Fourier transforms of the various possible time orderings. Finally, we extend our analysis to theories with $\mathcal{N}=1,2$ supersymmetry, where we find that the constraints due to the superconformal ward identities are identical to identities involving hypergeometric functions.
description: 28+6 pages
Entwicklung und Evaluation der nationalen Gesundheitsziele für Kinder und Jugendliche
Creators: name: Lampert, Thomas
name: Mensink, Gert
name: Hölling, Heike
name: Schlack, Robert
name: Kleiser, Christina
name: Kurth, Bärbel-Maria
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2009
Subjects: subject: Gesundheitsziele
subject: Jugendliche
subject: Kinder
subject: Ernährung
subject: Körperliche Aktivität
subject: Psychische Gesundheit
subject: Kinder- und Jugendgesundheitssurvey
subject: Adolescents
subject: Children
subject: Health targets
subject: Nutrition
subject: Physical exercise
subject: Mental health
subject: National Health Interview and Examination Survey for Children and Adolescents
subject: 610 Medizin

description: Gesundheitsziele werden zunehmend zu einem Steuerungsinstrument der Gesundheitspolitik im nationalen und internationalen Kontext. Im Projekt gesundheitsziele.de wurden mit Blick auf Kinder und Jugendliche in Deutschland bislang Ziele zu den Themenbereichen Ernährung, Bewegung und Stressbewältigung formuliert. Für die Umsetzung und Evaluation der Gesundheitsziele sind regelmäßig bereitgestellte, aussagekräftige Daten erforderlich, die eine umfassende und präzise Beschreibung der relevanten Problemlagen und Entwicklungen erlauben. Mit dem Kinder- und Jugendgesundheitssurvey, der vom Robert Koch-Institut im Zeitraum 2003 bis 2006 durchgeführt wurde, steht eine Datenbasis zur Verfügung, die Informationen zu beinahe allen Facetten der gesundheitlichen Entwicklung im Kindes- und Jugendalter verfügbar macht und zur Feststellung der Ausgangslage des Gesundheitszieleprozesses herangezogen werden kann. Das vorliegende Papier beschreibt, welche Daten der Survey zu den Zielbereichen Ernährung, Bewegung und Stressbewältigung bereitstellt und welchen Beitrag diese zur Weiterentwicklung und Umsetzung der Gesundheitsziele für Kinder und Jugendliche leisten könnten.
description: Health targets are increasingly becoming a health-policy control instrument, both nationally and internationally. In the project gesundheitsziele.de, targets have been formulated for children and adolescents in Germany – currently in the areas of nutrition, exercise, and stress management. Implementing and evaluating health targets requires regularly updated, informative data that allow a comprehensive and precise description of the relevant problems and developments. The Robert Koch Institute’s National Health Interview and Examination Survey for Children and Adolescents – conducted during the period from 2003 to 2006 – provides a pool of data with information on virtually all facets of health development during childhood and adolescence which can be used to determine the starting point of the health-targeting process. This article describes the data provided by the survey of the areas nutrition, exercise, and stress management and the contribution these data could make towards further developing and implementing the health targets for children and adolescents.
sj-pdf-6-cep-10.1177_03331024211024160 - Supplemental material for Randomised, controlled trial of erenumab for the prevention of episodic migraine in patients from Asia, the Middle East, and Latin America: The EMPOwER study
Creators: name: Wang, Shuu-Jiun
name: Roxas, Artemio A
name: Saravia, Bibiana
name: Kim, Byung-Kun
name: Chowdhury, Debashish
name: Riachi, Naji
name: Tai, Mei-Ling Sharon
name: Tanprawate, Surat
name: Ngoc, Tai Tran
name: Jing, Zhao Yi
name: Mikol, Daniel D
name: Pandhi, Shaloo
name: Wen, Shihua
name: Mondal, Subhayan
name: Tenenbaum, Nadia
name: Hours-Zesiger, Peggy
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, sj-pdf-6-cep-10.1177_03331024211024160 for Randomised, controlled trial of erenumab for the prevention of episodic migraine in patients from Asia, the Middle East, and Latin America: The EMPOwER study by Shuu-Jiun Wang, Artemio A Roxas JrBibiana Saravia, Byung-Kun Kim, Debashish Chowdhury, Naji Riachi, Mei-Ling Sharon Tai, Surat Tanprawate, Tai Tran Ngoc, Zhao Yi Jing, Daniel D Mikol, Shaloo Pandhi, Shihua Wen, Subhayan Mondal, Nadia Tenenbaum and Peggy Hours-Zesiger in Cephalalgia
Lyme-Borreliose: Ein Situationsbericht aus den sechs östlichen Bundesländern 2007–2009
Creators: name: Adlhoch, Cornelia
name: Poggensee, Gabriele
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2010
Subjects: subject: Umweltmedizin
subject: Gesundheit
subject: UMID
subject: Umwelt
subject: Mensch
subject: Informationsdienst
subject: Verbraucherschutz
subject: Borreliose
subject: 610 Medizin

description: Lyme Borreliosis is a notifiable disease in the Federal States of Berlin, Brandenburg, Mecklenburg-West-Pomerania, Saxony, Saxony-Anhalt und Thuringia. With 16.461 reported cases between 2007 and 2009 (until 1.12.2009) Lyme borreliosis belongs to the most common vector-borne diseases. In the years 2007 to 2009 the highest number of cases was registered within the months of June to September, with the onset of disease between June and August. The incidence rates were heterogeneously distributed within the Federal States with the highest rates in regions close to the river Oder and to the border to Poland in Brandenburg and Saxony. A bimodal distribution was seen with highest incidence rates in the age groups between 5 to 9 and 60 to 64 years. More women were affected than men. The most frequent notifiable clinical manifestation of Lyme borreliosis was erythema migrans. Only a few cases of early neuroborreliosis and lyme arthritis were reported. Hospitalisation was necessary for 280 patients in the years 2007–2009, mostly with neuroborreliosis. Although no epidemiological data throughout Germany are available it can be assumed that a nationwide but locally different risk of transmission via infected ticks exists.
sj-pdf-1-jaf-10.1177_0148558X211022946 – Supplemental material for Tournament Incentives and Corporate Social Responsibility Performance
Creators: name: Zhao, Xuezhou (Rachel)
name: Zhou, Gaoguang (Stephen)
name: Rezaee, Zabihollah
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business

description: Supplemental material, sj-pdf-1-jaf-10.1177_0148558X211022946 for Tournament Incentives and Corporate Social Responsibility Performance by Xuezhou (Rachel) Zhao, Gaoguang (Stephen) Zhou and Zabihollah Rezaee in Journal of Accounting, Auditing & Finance
X-Shooting ULLYSES: Massive Stars at low metallicity II. DR1: Advanced optical data products for the Magellanic Clouds
Creators: name: Sana, H.
name: Tramper, F.
name: Abdul-Masih, M.
name: Blomme, R.
name: Dsilva, K.
name: Maravelias, G.
name: Martins, L.
name: Mehner, A.
name: Wofford, A.
name: Banyard, G.
name: Barbosa, C. L.
name: Bestenlehner, J.
name: Hawcroft, C.
name: Hillier, D. John
name: Todt, H.
name: Larkin, C. J. K.
name: Mahy, L.
name: Najarro, F.
name: Ramachandran, V.
name: Ramirez-Tannus, M. C.
name: Rubio-Diez, M. M.
name: Sander, A. A. C.
name: Shenar, T.
name: Vink, J. S.
name: Backs, F.
name: Brands, S. A.
name: Crowther, P.
name: Decin, L.
name: de Koter, A.
name: Hamann, W. -R.
name: Kehrig, C.
name: Kuiper, R.
name: Oskinova, L.
name: Pauli, D.
name: Sundqvist, J.
name: Verhamme, O.
name: collaboration, the XSHOOT-U
Publisher: name: arXiv
Year: 2024
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Using the medium resolution spectrograph X-shooter, spectra of 235 OB and Wolf-Rayet (WR) stars in sub-solar metallicity environments have been secured. [...]This second paper focuses on the optical observations of 232 Magellanic Clouds targets. It describes the uniform reduction of the UVB (300 - 560 nm) and VIS (550 - 1020 nm) XShootU data as well as the preparation of advanced data products [...] . The data reduction of the raw data is based on the ESO CPL X-shooter pipeline. We paid particular attention to the determination of the response curves [...] We implemented slit-loss correction, absolute flux calibration, (semi-)automatic rectification to the continuum, and a correction for telluric lines. The spectra of individual epochs were corrected for the barycentric motion, re-sampled and co-added, and the spectra from the two arms were merged into a single flux calibrated spectrum covering the entire optical range with maximum signal-to-noise ratio. [...] We provide three types of data products: (i) two-dimensional spectra for each UVB and VIS exposure; (ii) one-dimensional UVB and VIS spectra before and after response-correction, as well as after applying various processing, including absolute flux calibration, telluric removal, normalisation and barycentric correction; and (iii) co-added flux-calibrated and rectified spectra over the full optical range, for which all available XShootU exposures were combined. For many of the targets, the final signal-to-noise ratio per resolution element is above 200 in both the UVB and the VIS co-added spectra. The reduced data and advanced scientific data products will be made available to the community upon publication of this paper. [...]
description: 22 pages, 19 figures; accepted for publication in Astronomy & Astrophysics. Links to online tables and databases will be included upon publication
Beneficial and detrimental effects of human endogenous retroviruses
Creators: name: Kurth, Reinhard
name: Bannert, Norbert
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2009
Subjects: subject: Animals
subject: Molecular
subject: Humans
subject: Gene Expression Regulation
subject: Human/genetics
subject: Endogenous Retroviruses/genetics
subject: Evolution
subject: Genome
subject: Mutagenesis
subject: Insertional
subject: Neoplasms/genetics
subject: Retroelements/genetics
subject: Retroviridae/genetics
subject: 610 Medizin

description: In this mini review, we aim to evaluate the structure and function of Human Endogenous Retroviruses (HERVs) with respect to the benefit they may have for humans or the damage they may cause. Emphasis is laid on their putative roles, if any, in pregnancy, in gene regulation and in cancer. As a basis for this discussion it will first be necessary to briefly describe the structure and function of retroelements, including HERVs, before addressing their positive or negative effects at the cellular and organismal level. Finally, we will give an outlook in which we will attempt to define priorities for future research.
Modelling LAEs in the Epoch of Reionization with OBELISK
Creators: name: Giovinazzo, Emma
name: Trebitsch, Maxime
name: Mauerhofer, Valentin
name: Dayal, Pratika
name: Oesch, Pascal A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Lya emitters (LAEs) are particularly useful objects for the study of the Epoch of Reionization. Lya profiles can be used to estimate the amount of ionizing photons that are able to escape the galaxies, and therefore to understand what objects contributed to reionization. However, Lya is a resonant line and its complex radiative transfer effects make the interpretation of the line challenging and require the use of appropriate radiative transfer methods for anything but the simplest gas distributions. With this work we aim to study the properties of simulated LAEs, and the robustness of these inferred properties under a change in the dust model. We also explore the Lyman Continuum (LyC) escape fraction of these galaxies and compare our results with observationally calibrated methods to infer this quantity from the Lya spectrum. We use the radiative transfer code RASCAS to perform synthetic observations of 13 flux-selected galaxies from the Obelisk simulation at redshift z = 6, towards the end of the Epoch of Reionization. Each galaxy was observed in Lya, ionizing and non-ionizing continuum from 48 different viewing angles. We show that the Lya profiles emitted from a galaxy present large variations with a change in viewing angle and that the relation between peak separation and Lya escape fraction is not as strong as previously found, as we find lines of sight with both low peak separation and low escape fraction, due to their dust content. We also show that the properties of the Lya line are reasonably robust under a change in dust model. Lastly, we compare the LyC escape fractions we derive from the simulation to three observationally calibrated methods of inferring this quantity. We determine that none of these relations reproduce the scatter that we find in our sample, and that high escape fraction lines of sight have both low peak separation and low dust extinction in the UV.
description: Resubmitted to A&A after the first referee report
Recurrent chaotic clustering and slow chaos in adaptive networks
Creators: name: Sales, Matheus Rolim
name: Yanchuk, Serhiy
name: Kurths, Jürgen
Publisher: name: arXiv
Year: 2024
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Adaptive dynamical networks are network systems in which the structure co-evolves and interacts with the dynamical state of the nodes. We study an adaptive dynamical network in which the structure changes on a slower time scale relative to the fast dynamics of the nodes. We identify a phenomenon we refer to as recurrent adaptive chaotic clustering (RACC), in which chaos is observed on a slow time scale, while the fast time scale exhibits regular dynamics. Such slow chaos is further characterized by long (relative to the fast time scale) regimes of frequency clusters or frequency-synchronized dynamics, interrupted by fast jumps between these regimes. We also determine parameter values where the time intervals between jumps are chaotic and show that such a state is robust to changes in parameters and initial conditions.
Evaluation of serological diagnostic test systems assessing the immune response to Japanese encephalitis vaccination.
Creators: name: Litzba, Nadine
name: Klade, Christoph S.
name: Lederer, Sabine
name: Niedrig, Matthias
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2010
Subjects: subject: Humans
subject: Female
subject: Male
subject: Antibodies
subject: Immunoglobulin M/blood
subject: Vaccination
subject: Encephalitis
subject: Immunoglobulin G/blood
subject: Immunoglobulin G/immunology
subject: Immunoglobulin M/immunology
subject: Antibodies Viral/blood
subject: Viral/diagnostic use
subject: Antibodies Viral/immunology
subject: Encephalitis Virus Japanese/immunology
subject: Encephalitis Virus
subject: Japanese/isolation & purification
subject: Japanese/diagnosis
subject: Japanese/immunology
subject: Japanese/prevention & control
subject: Japanese/virology
subject: Fluorescent Antibody Technique Indirect/methods
subject: Immunity Humoral
subject: Immunoglobulin G/diagnostic use
subject: Immunoglobulin M/diagnostic use
subject: Japanese Encephalitis Vaccines/administration & dosage
subject: Japanese Encephalitis Vaccines/immunology
subject: 610 Medizin

description: A new commercial anti-Japanese encephalitis virus IgM and IgG indirect immunofluorescence test (IIFT) was evaluated for the detection of the humoral immune response after Japanese encephalitis vaccination. The IgM IIFT was compared to two IgM capture ELISAs and the IgG IIFT was analysed in comparison to a plaque reduction neutralization test (PRNT50) and an IgG ELISA. Moreover, the course of the immune reaction after vaccination with an inactivated JEV vaccine was examined. For the present study 300 serum samples from different blood withdrawals from 100 persons vaccinated against Japanese encephalitis were used. For the IgM evaluation, altogether 78 PRNT50 positive samples taken 7 to 56 days after vaccination and 78 PRNT50 negative sera were analyzed with the Euroimmun anti-JEV IgM IIFT, the Panbio Japanese Encephalitis – Dengue IgM Combo ELISA and the InBios JE Detect IgM capture ELISA. For the IgG evaluation, 100 sera taken 56 days after vaccination and 100 corresponding sera taken before vaccination were tested in the PRNT50, the Euroimmun anti-JEV IgG IIFT, and the InBios JE Detect IgG ELISA. The Euroimmun IgM IIFT showed in comparison to the Panbio ELISA a specificity of 95% and a sensitivity of 86%. With respect to the InBios ELISA, the values were 100% and 83.9%, respectively. The analysis of the Euroimmun IgG IIFT performance and the PRNT50 results demonstrated a specificity of 100% and a sensitivity of 93.8%, whereas it was not possible to detect more than 6.6% of the PRNT50 positive sera as positive with the InBios JE Detect IgG ELISA. Thus, the IIFT is a valuable alternative to the established methods in detecting anti-JEV antibodies after vaccination in travellers and it might prove useful for the diagnosis of acutely infected persons.
Additional file 1 of Views and experiences of healthcare professionals and patients on the implementation of a 23-hour accelerated enhanced recovery programme: a mixed-method study
Creators: name: Sier, Misha A. T.
name: Godina, Eva
name: Tweed, Thaís T. T.
name: Daher, Imane
name: Stoot, Jan H. M. B.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Cancer
Mental Health

description: Supplementary Material 1.
Rickettsia aeschlimannii in Hyalomma marginatum Ticks, Germany
Creators: name: Rumer, Leonid
name: Graser, Elmara
name: Hillebrand, Timo
name: Talaska, Thomas
name: Dautel, Hans
name: Mediannikov, Oleg
name: Roy-Chowdhury, Panchali
name: Sheshukova, Olga
name: Mantke, Oliver Donoso
name: Niedrig, Matthias
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2011
Subjects: subject: Animals
subject: Phylogeny
subject: Polymerase Chain Reaction
subject: Germany/epidemiology
subject: Species Specificity
subject: Rickettsia/classification
subject: Tick Infestations/parasitology
subject: RNA Ribosomal 16S/genetics
subject: DNA Ribosomal Spacer/analysis
subject: Ixodidae/classification
subject: Ixodidae/genetics
subject: Ixodidae/microbiology
subject: Rickettsia/genetics
subject: Rickettsia/isolation & purification
subject: Rickettsia Infections/microbiology
subject: Rickettsia Infections/transmission
subject: Tick Infestations/epidemiology
subject: 610 Medizin

description: To the Editor: Rickettsia spp. of the spotted fever group cause worldwide emerging human infections known as tick-borne rickettsioses (1). Data on the occurrence and prevalence of Rickettsia in Germany are still limited (2). Six Rickettsia species have been reported to date (2). R. helvetica, R. felis, R. massiliae, and R. monacensis were detected with a relatively low prevalence in Ixodes ricinus ticks collected in southern Germany (2); R. raoultii was identified with high prevalence in the rapidly expanding area where D. reticulatus ticks are found (2). R. raoultii was recently recognized as an agent of tick-borne lymphadenopathy/Dermacentor-borne necrosis and erythema lymphadenopathy (3). Low prevalence of another tick-borne lymphadenopathy agent, R. slovaca, in Dermacentor marginatus ticks collected in southern Germany was recently reported (4).
Frühe Weichenstellung
Creators: name: Lampert, Thomas
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2010
Subjects: subject: Kinder- und Jugendgesundheit
subject: Chronische Krankheiten
subject: Soziale Ungleichheit
subject: Prävention und Gesundheitsförderung
subject: Lebenslauf
subject: Chronic diseases
subject: Social inequality
subject: Health of children and adolescents
subject: Prevention and health promotion
subject: Life course
subject: 610 Medizin

description: Vor dem Hintergrund der voranschreitenden Alterung der Bevölkerung und der Diskussion über die sich daraus ergebenden gesellschaftlichen Herausforderungen wird der Frage nachgegangenen, welche Bedeutung der Kindheit und Jugend für die Gesundheit im späteren Leben zukommt. Dazu werden die bisherigen Erkenntnisse der epidemiologischen Lebenslaufforschung beschrieben, die unter anderem auf den Zusammenhang zwischen frühen organischen Schädigungen und dem Krankheitsrisiko im mittleren und höheren Lebensalter, auf die Kumulation von Risiken und Ressourcen über den gesamten Lebenslauf und den Einfluss der Lebensbedingungen und Lebenschancen auf die gesundheitliche Entwicklung verweisen. Außerdem wird auf Grundlage der in Deutschland verfügbaren Daten die gesundheitliche Situation von Kindern und Jugendlichen dargestellt, um auf vorhandene Problemlagen hinzuweisen und Präventionspotenziale und Handlungsmöglichkeiten kenntlich zu machen.
description: The article examines the importance of childhood and adolescence for health in later life against the background of the population-aging process and the debate on the social challenges expected to result from this process. In this context, it describes the findings of life course epidemiology, which suggest (among other things) that there is a connection between early organic damage and the risk of illness in middle and old age, that risks and resources accumulate throughout a person’s lifespan, and that living conditions and opportunities in life influence the development of health. The article also describes the health situation of children and adolescents based on the data available in Germany, in order to draw attention to existing problems and to identify possible ways of preventing them and taking action.