cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The influence of dielectric properties on van der Waals/Casimir forces in solid-liquid systems
Creators: name: van Zwol, P. J.
name: Palasantzas, G.
name: De Hosson, J. Th. M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: In this article we present calculations of van der Waals/Casimir forces, described by Lifshitz theory, for the solid-liquid-solid system using measured dielectric functions of all involved materials for the wavelength range from millimeters down to subnanometers. It is shown that even if the dielectric function is known over all relevant frequency ranges, the scatter in the dielectric data, can lead to very large scatter in the calculated van der Waals/Casimir forces. Especially when the liquid dielectric function becomes comparable in magnitude to the dielectric function of one of the interacting solids, the associated variation in the force can be up to a factor of two for plate-plate separations 5-500 nm. This corresponds to an uncertainty up to 100% in the theory prediction for a specific system. As a result accuracy testing of the Lifshitz theory under these circumstances is rather questionable. Finally we discuss predictions of Lifshitz theory regarding multiple repulsive-attractive transitions with separation distance, as well as nontrivial scaling of the van der Waals/Casimir force with distance.
description: 32 pages, 11 figures
Primi risultati per CUORE
Creators: Eleonora Cossi
Publisher: name: Media Inaf
Year: 2015

Lo studio, centrato sui decadimenti rarissimi dei nuclei di tellurio, indica con precisione mai raggiunta prima per questi nuclei la regione in cui cercare un fenomeno che coinvolge i neutrini e che, secondo i fisici, potrebbe fornire informazioni chiave sull’asimmetria tra materia e antimateria nel nostro universo
Ultrastructural aspects of mineralization-induced modifications in turkey tendon
Creators: name: Raspanti,
name: Reguzzoni, Marcella
name: Protasoni, Marina
name: Congiu, Terenzio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Extracellular Matrix; Tendon; Crimps; SEM; Mineralization.

description: In all tendons the collagen fascicles follow a wavy course (actually a flattened lefthanded helix) forming visible crimps. Each crimp corresponds to a sharp bend and/ or an axial twisting of individual collagen fibrils (Raspanti et al., 2005; Franchi et al., 2010), and even once the fibril are straightened out a permanent local deformation remains visible, still revealing the original crimp location (Raspanti et al., 2005). The tendons of some birds represent a special case as they undergo a physiological process of gradual mineralization involving heavy modifications of the tissue architecture. In the present research, turkey tendons appeared to be more finely subdivided into thinner fascicles than most tendons; they contained a greater amount of cell-rich endotenon tissue as well as occasional nodules of cartilage-like matrix. The most striking finding, however, was the complete disappearance of the crimps in the calcified portions of the tendon, while they were present with the usual morphology in the non-mineralized portion. The mineralized fibrils ran perfectly straight, but the electron microscopy revealed traces of pre-existing crimps locked in the extended position by the mineralization process. The inorganic phase itself appeared composed of two different types of fine particles, respectively growing inside or around the collagen fibrils and looking as tightly packed fine needles or as larger platelets regularly arranged in relation with the D-period. The perifibrillar mineral could play a critical role in the mechanical coupling of adjoining fascicles and in the transmission of tensile loads along the tendon itself.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Mixing of S-Wave Charmonia with $\mathrm{D}\overline{\mathrm{D}}$ Molecule States
Creators: name: Bali, Gunnar
name: Ehmann, Christian
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Charmonium states can decay into pairs of $D$ and $\overline{D}$ mesons if their masses are above the allowed decay thresholds. In general $c\bar{c}$ states near threshold will also undergo mixing with $D\overline{D}$ molecular (or tetraquark) states, by creation and annihilation of light quark-antiquark pairs. The investigation of such effects sheds light on the higher Fock state contributions to charmonium wavefunctions and on mass shifts, relative to a scenario where such mixing effects are neglected. A variational approach is applied to a mixing matrix between operators of both sectors, of $c\bar{c}$ and of $D\overline{D}$ molecular type. The efficient calculation of several diagrams appearing in this matrix requires all-to-all propagators, which are realized by sophisticated stochastic estimator techniques. The runs are performed on $n_F=2$ $24^3\times 48$ lattice volumes with $m_π \approx 280$ MeV, using the non-perturbatively improved clover Wilson action, both for valence and for sea quarks.
description: 7 pages, 4 figures. Poster presented at the "XXVII International Symposium on Lattice Field Theory", July 26-31 2009, Peking University, Beijing, China
title: ÐÐ²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ñ Ð²ÑÐ±Ð¾ÑÐ° Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ð° ÑÐµÐ¶ÑÑÐµÐ¹ ÑÐ°ÑÑÐ¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ° Ð¿ÑÐ¸ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐµ ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ð¹ Ð¼ÐµÑ Ð°Ð½Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð·Ð°Ð³Ð¾ÑÐ¾Ð²Ð¾Ðº
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°ÑÑÐµÐ½ÐºÐ¾, ÐÑÐ¸ÑÑÐ¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: Ð¼ÐµÑ Ð°Ð½Ð¸ÑÐµÑÐºÐ°Ñ Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ°
Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ°Ð»ÑÐ½ÑÐµ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ñ
Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ñ
machining
tool materials
automation

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description: This bachelor work is to study one of the ways to automate the selection of the material of the cutting tool for processing workpieces of different materials. We present all the necessary information on the tool materials, heat treatment regimes blanks and block diagram of the program for the PC. An example of the program for automatic selection depending upon the properties of the processed material.
Introducing medical students to scientific research: an early electron-microscopy laboratory attendance experience
Creators: name: Relucenti, Michela
name: Battaglione, Ezio
name: Heyn, Rosemarie
name: Familiari, Giuseppe
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Electron microscopy; medical education; learning by doing; active learning.

description: In the light of importance that “evidence-based medicine” has assumed in recent years (Snelgrove et al. 2009), we offer to the students of the first-year medical-degree the chance of an early exposure to the work in the ultrastructural research laboratory “Pietro M. Motta”. On an elective basis, students attended the laboratory in small groups. They were guided and supported by a qualified researcher, a post-graduate student, a graduate student and a technical-staff unit. During the week of attendance students performed several activities: at first they have visited the laboratory where the technicalities of the equipment were illustrated, than they have taken part to a lecture on the methods used to prepare the biological samples for Scanning and Transmission Electron Microscopy. In the following days preparation of samples for Scanning and Transmission Electron Microscopy was carried on and a guided discussion on scientific articles concerning the samples used in the experiments was conducted (Familiari et al. 2006). Later, samples were observed using a light microscope and both transmission and scanning electron microscope. At the end of the week students had taken hands-on in various stages of preparation, observation and analysis of the samples. The discussion with the researcher and the post-graduate doctors/ students provided the attendant students with key concepts regarding scientific work that are the basis of theory and practice of biomedical research projects, not only of ultrastructural type. The students’ early exposure to the work and methodology characteristic of ultrastructural research may prove useful, not only when promoting indepth understanding of microscopic anatomy, but also as a motivational base upon which to instil a correct approach to scientific research in future doctors.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Il Dna della Terra è lo stesso della Luna
Creators: Corrado Ruscica
Publisher: name: Media Inaf
Year: 2015

Da uno studio sulla composizione isotopica delle rocce lunari, un gruppo di ricercatori dell'Università del Maryland ritiene di aver trovato il tassello mancante che potrebbe spiegare l'origine della formazione della Luna. L'analisi dei dati supporta l'ipotesi secondo cui il materiale creatosi dall'impatto si deve essere mescolato prima che iniziasse il processo di aggregazione e di raffreddamento della Luna, il che spiegherebbe le molte similitudini isotopiche tra la Terra e la Luna. I risultati su Nature
title: ÐÐ½Ð¾Ð³Ð¾ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½ÑÐ¹ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑ Ñ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾-Ð¿ÐµÑÐµÑÐ°Ð´Ð¾ÑÐ½ÑÐ¼ ÑÐ·Ð»Ð¾Ð¼
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° ÑÐ¿ÐµÑÐ¸Ð°Ð»Ð¸ÑÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°ÑÐºÐ¸Ð½Ð°, ÐÐ¾Ð»Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾-Ð¿ÐµÑÐµÑÐ°Ð´Ð¾ÑÐ½ÑÐ¹ ÑÐ·ÐµÐ»
Ð¿Ð¾Ð´Ð·ÐµÐ¼Ð½ÑÐ¹ Ð¿Ð°ÑÐºÐ¸Ð½Ð³

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½ Ð¼Ð½Ð¾Ð³Ð¾ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½ÑÐ¹ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑ Ñ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾-Ð¿ÐµÑÐµÑÐ°Ð´Ð¾ÑÐ½ÑÐ¼ ÑÐ·Ð»Ð¾Ð¼. ÐÐ´ÑÐµÑ ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ð°: Ð³. Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³, ÐÐ°ÑÐ¸Ð»ÐµÐ¾ÑÑÑÐ¾Ð²ÑÐºÐ¸Ð¹ ÑÐ°Ð¹Ð¾Ð½, 24-Ñ Ð»Ð¸Ð½Ð¸Ñ Ð.Ð., Ð´. 15/2.
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title: Ð£Ð¿ÑÐ°Ð²Ð»ÐµÐ½ÑÐµÑÐºÐ¸Ð¹ ÑÑÐµÑ
title: Ð¿ÑÐ°ÐºÑÐ¸ÐºÑÐ¼
titleType: Subtitle
Creators: name: Ð¡ÑÐ»Ð¾ÐµÐ²Ð°, Ð¡Ð²ÐµÑÐ»Ð°Ð½Ð°
name: ÐÐ±ÑÑÐ¾Ð²Ð°, ÐÐºÐ°ÑÐµÑÐ¸Ð½Ð°
name: ÐÑÑÐ¾Ð²Ð°, ÐÐºÐ°ÑÐµÑÐ¸Ð½Ð°
name: ÐÐµÐ¿Ð¿, ÐÐ°ÑÐ°Ð»ÑÑ
name: ÐÑÑÐ°Ð½Ð¾Ð²Ð°, ÐÐ°ÑÐ°Ð»ÑÑ
name: Ð¡ÑÐµÐ¿Ð°Ð½ÑÑÐº, ÐÐ½Ð´ÑÐµÐ¹
Publisher: name: ÐÐÐÐÐ¢ÐÐ¥-ÐÐ ÐÐ¡Ð¡
Year: 2020
Subjects: ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½ÑÐµÑÐºÐ¸Ð¹ ÑÑÐµÑ
Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð·Ð°Ð½ÑÑÐ¸Ñ
ÑÑÐµÐ±Ð½Ð¸ÐºÐ¸ Ð¸ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ Ð´Ð»Ñ Ð²ÑÐ·Ð¾Ð²

description: ÐÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½ Ð´Ð»Ñ ÑÐ³Ð»ÑÐ±Ð»ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¸Ð·ÑÑÐµÐ½Ð¸Ñ Ð»ÐµÐºÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ ÐºÑÑÑÐ° Ð¸ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð¸Ñ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð½Ð°Ð²ÑÐºÐ¾Ð² Ð¿Ð¾ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½Ðµ Â«Ð£Ð¿ÑÐ°Ð²Ð»ÐµÐ½ÑÐµÑÐºÐ¸Ð¹ ÑÑÐµÑÂ» Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð¸Ñ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¿ÑÐ¸Ð¼ÐµÑÐ¾Ð² Ð¸ ÑÐ¸ÑÑÐ°ÑÐ¸Ð¹. ÐÐµÑÐ¾Ð´Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ñ, Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð·Ð°Ð´Ð°ÑÐ¸ Ð¸ ÐºÐ¾Ð½ÑÑÐ¾Ð»ÑÐ½ÑÐµ Ð²Ð¾Ð¿ÑÐ¾ÑÑ Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÑÑ ÑÑÑÐ´ÐµÐ½ÑÐ°Ð¼ Ð½ÐµÐ¿ÑÐµÑÑÐ²Ð½Ð¾ Ð¸ Ð³Ð»ÑÐ±Ð¾ÐºÐ¾ Ð¸Ð·ÑÑÐ°ÑÑ ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¸ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÑÐ°Ð·Ð´ÐµÐ»Ñ ÐºÑÑÑÐ°.
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I mattoni della vita nel disco protoplanetario
Creators: Ufficio stampa Inaf
Publisher: name: Media Inaf
Year: 2015

Per la prima volta gli astronomi hanno scoperto la presenza di molecole organiche complesse, i mattoni della vita, in un disco protoplanetario che circonda una giovane stella. La scoperta, realizzata con ALMA (Atacama Large Millimeter/submillimeter Array), riconferma che le condizioni in cui hanno avuto origine la Terra e il Sole non sono uniche nell'Universo. I risultati vengono pubblicati nel numero del 9 aprile 2015 della rivista Nature
Gli astronauti si danno al giardinaggio
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2015

I ricercatori cercano di studiare come i vegetali reagiscono alla crescita in microgravità e sembra proprio che riescano a crescere verso l'alto come accade sulla Terra. Lo studio Plant Gravity Sensing è ancora in corso, quindi è presto per dare dei veri e proprio risultati certi, ma in futuro potrebbe essere possibile coltivare piante durante missioni spaziali di lunga durata o, chissà, su altri pianeti
COX and VEGFR-2 inhibitors as potentiating agents of new HDAC inhibitors as epigenetic modulators in cancer
Creators: name: Renzi, Anastasia
name: Ragno, Rino
name: Mancinelli, Romina
name: Franchitto, Antonio
name: Mai, Antonello
name: Gaudio, Eugenio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: HDACI; VEGFR-2 and COX-2 inhibitors; antiproliferative effects.

description: Recently, among anticancer agents, of growing interest are the kinases inhibitors. Many of them are under clinical trials while some have been already approved by FDA as angiogenesis blockers (Vascular endothelial growth factor receptor 2 (VEGFR- 2) inhibitors), such as Sunitinib and Vandetanib. HDACI (histone deacetylase inhibitors) are another newest drug group recently approved for the treatment of Cutaneous T-cell lymphoma (CTCL) (Wagner et al., 2010) and several others HDACIs are in pre-clinical and clinical stages. Interestingly, many scientific reports indicate the synergistic effects of the HDACI and VEGFR-2 inhibitors combination. Lately, has been proposed and showed that cycle oxygenases (COXs) inhibitors could reduce the adverse side effects upon HDACI administration. Furthermore, the anticancer effectiveness of COX-2 inhibitors in the treatment of gastric cancer animal models has been demonstrated (Thiel et al., 2011). Taking consideration of these observations we aim to study a new antiproliferative therapy with the combined use of three potentially synergic drug classes: HDACI, inhibitors of VEGFR-2 and COX-2. The antitproliferative evaluation of the more promising molecules will be evaluated both in vitro, in colangiocarcinoma and hepatocarcinoma cell lines trough MTT proliferation assay and Caspase3 Elisa kit, and in vivo models. Along with individual compound assays, synergistic effects will be also determined. The main findings derived from individual compound assay studies will be integrated and used to set-up the best combination of compounds for a multi-target approach that we expect to be highly effective against cancer.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Anti-proliferative and anti-migratory effects of baicalin on cholangiocarcinoma cell line EGI-1
Creators: name: Rigolio, Roberta
name: Cadamuro, Massimiliano
name: Caramia, Grazia
name: Malacrida, Alessio
name: Maggioni, Daniele
name: Foudah, Dana
name: Miloso, Mariarosaria
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Cholangiocarcinoma; EGI-1 cells; Baicalin; cell viability; cell migration.

description: Cholangiocarcinoma (CCA) is the second most frequent primary liver neoplasia. It mainly arises from the malignant transformation of biliary epithelial cells, although it might originate from either hepatic progenitor cells at the Hering canals or transformed hepatocytes. CCA is a highly aggressive tumor with extremely poor prognosis and limited therapeutic approaches. Baicalin (BA) is one of the main bioactive flavonoids identified in the Scutellaria Baicalensis Georgi root dried extract which is extensively used in the Chinese traditional medicine. Together with the anti-inflammatory effect, the anti-neoplastic action is the most relevant BA property demonstrated on cancer cells of different origin. Being aware of the need of new therapeutic weapons for CCA treatment, we investigated whether Baicalin could exert anti-proliferative and anti-migratory effect on EGI-1 cells, a highly metastatic CCA cell line derived from bile duct carcinoma. We first tested different BA concentrations (from 5 to 200μM) in limiting EGI-1 viability using MTT assay. After 24h and 48h treatment, 5 and 10μM BA had no effect while rising from 25μM to 200μM (i.e. 25, 50, 100 and 200μM) BA exerted a significant cell viability reduction already at 24h and increased after 48h BA exposure. This reduction well correlated with the adherent absolute cell number decrease and it cannot be due to BA induced cell cycle impairment after neither 24 nor 48h treatment. We also evaluated the anti-migratory BA potential by a wound healing assay adding different BA concentrations (5, 25, 50,100 and 200μM) to the culture medium immediately after performing a wound on confluent cell cultures. All BA concentrations but 5μM induced a significant reduction in the EGI-1 migration rate after 24h treatment. Moreover 25, 50 and 10μM BA showed similar migration inhibition extent at 24 and 48h whilst 200μM BA exerted a stronger inhibitory effect already after 24h exposure which increased with time in a significant way. Taken together our preliminary results demonstrate that BA impairs CCA cell viability and migration suggesting a promising adjuvant therapeutic use for BA as antitumoral agent.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Variational approach for Bose-Einstein condensates in strongly disordered traps
Creators: name: Falco, G. M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: Recently, Nattermann and Pokrovsky [PRL 100, 060402 (2008)] have proposed a scaling approach for studying Bose-Einstein condensates in strongly disordered traps. In this paper we implement their scaling argument in the framework of the variational method for solving the time dependent Gross-Pitaevskii equation. We consider atomic gases with both short range s-wave interaction and long range anisotropic dipolar interaction. The theory is addressed to the regime of strong disorder and weak interactions where the physics is dominated by the collective pinning due to the disorder. The phenomenon of condensate fragmentation in dipolar gases is also analyzed.
Addio a Giorgio Salvini
Creators: Ufficio stampa Inaf
Publisher: name: Media Inaf
Year: 2015

È scomparso nella sua casa a Roma, all’età di 95 anni, Giorgio Salvini, fisico di fama internazionale e padre dei Laboratori di Frascati dell’INFN, il primo laboratorio nazionale di fisica delle particelle. Era nato a Milano il 24 aprile del 1920
Effects of an innovative esoskeleton (Human Body Posturizer) on static balance in patients with Parkinson’s Disease
Creators: name: Ripani, Maurizio
name: Aprile, Irene
name: De Santis, Fabio
name: Ciccarelli, Antonello
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Esoskeleton; Human Body Posturizer; Parkinson’s disease.

description: Parkinson disease (PD) is a progressive neurodegenerative disease, affecting 0.3% of the general population; cardinal symptoms include tremor, rigidity, bradykinesia, and postural instability. Individuals with PD commonly experience gait and postural stability impairments, which may lead to falls, mobility loss, and reduced independence (de Lau et al, 2006). Human Body Posturizer (HBP) is a fully articulated orthosis, light and able to adapt to the physical characteristics of each individual (Di Russo et al, 2013). Our aim has been to preliminary evaluate the role of HBP as an innovative tool for the conservative treatment of gait and postural stability impairments in patients affected by PD. This study analyzed 10 subjects (5 male and 5 female) affected by PD. A bipodal platform (Prokin, Tecnobody) was used to evaluate static balance. All patients were firstly evaluated without HBP and wearing normal clothes; then, patients were asked to wear HBP and, after 40 mins, a second acquisition with HBP was performed. For the static evaluation, the patients performed a stabilometric test, 30 sec with eyes open and then 30 sec with eyes closed; perimeter sway, area of the center of pressure (CoP), anterior-posterior velocity (VA-P), and medial-lateral velocity (VM-L) have been evaluated. Our results showed a significant reduction in VA-P (p<0.05) when patients wear HBP in both open and closen eyes condition. Moreover, a significant reduction (p<0.05) of the CoP area was observed in closen eyes evaluation. Area of the ellipse contained 95% of CoP data points, computed by considering the main axes of the ellipse, estimated using principal component analysis. This variable reflects the ability of balance system to achieve body stability. Our data suggest a stabilizing effect of HBP on anterior-posterior balance, in patients with PD.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Eustachius’s Tabulae Anatomicae, in the 300dt anniversary of their publication by Lancisi in 1714 in Rome
Creators: name: Riva, A.
name: Conti, G.
name: Loy, F.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Eustachius; tabulae; Lancisi.

description: Around 1550 Bartolomaeus Eustachius (1510?-1574), the great rival of Vesalius, joined the medical faculty of the University La Sapienza in Rome, and there are records that in the years 1555-1566 he held there the chair of Practical Medicine, where he had his pupil Pier Matteo Pini as first sector. During his lifetime Eustachius published only the Opuscola Anatomica (Venetiis 1563/64) containing six libelli (booklets) among which are of seminal importance those on kidney, teeth, auditory organ, and venous system. In 1552, under the direction of Eustachius and his assistant Pier Matteo Pini, 47 tables, then engraved in copper, were prepared by the Roman artist Giulio de’ Musi. Although they were treasured by Eustachius who bequeathed them to the family of Pini, they were unpublished and lost, though were searched repeatedly even by the great Marcello Malpighi. The plates were eventually found and acquired by Pope Clemente XI through the efforts of his physician Giovanni Maria Lancisi who published them in 1714 with new captions for the original had been lost. The title page also bears the beautiful engraving drawn by Pietro Leone Ghezzi from Ascoli, a painter of the papal court, and author of the official portrait of Pope Clement XI. Even though they became to be known more than one century and a half after their completion, the tables arouse such interest and praise among the most prominent scientists of the early XVIII century that, besides that by Lancisi, other editions, with new legends and comments, were printed from the original copper blocks or from re-engravings. Among the latter the best reproduced and commented are those by B.S Albinus, Leyden 1744, that became the anatomy reference book for the rest of the century. Through Albinus, a friend of Felice Fontana, Eustachius’s tables served, according to some critics, as models for the muscle figures in wax exhibited in the museums of La Specola in Florence and in the Iosephinum in Vienna.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
title: Интересы студенческой молодежи в сфере социально-гуманитарной проблематики
Creators: name: Шапиро, С. В.
Publisher: name: Реноме
Year: 2023

description: Статья посвящена студенческим предпочтениям по социальной и гуманитарной проблематике, представленным в учебной активности на занятиях. Автор рассматривает содержание докладов студентов на семинарах по «человековедческим» дисциплинам. В результате анализа эмпирического материала выявлены основные группы важных для учащейся молодежи тем в сфере обществоведения. Представлена попытка типологизации этих интересов. Установлено, что приоритетная область — это экзистенциальные вопросы о сущности человека, о его месте в мире, смысле жизни, смерти и идеи бессмертия. Охарактеризованы некоторые новые, появившиеся в последнее время, тенденции в тематических блоках, субъективно и эмоционально актуальных для студентов. Показано, что в сложной стремительно меняющейся реальности актуальной задачей взросления является потребность в социальной и личностной идентичности.
Connective tissue lung: different composition between male and female
Creators: name: Rizzo, Giuseppina
name: Monaco, Maurizio
name: Santoro, Giuseppe
name: Anastasi, Giuseppe
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015

description: Abnormal elasticity of lung tissue has a major impact on the clinical progression and outcome of many lung diseases including respiratory distress syndrome, asthma, emphysema and pneumothorax post thoracic injury. The major components of lung connective tissue are elastin, collagen and together provide the lung with its elasticity and tensile strength. Elastin is composed of flexible cross-linked polypeptides and has a linear stress-strain relation up to 200% strain; collagen has a more organized structure with both crystalline and amorphous phases and exhibits a highly unlinear stress-strain curve. The thoracic injury is responsible for about 25% of death for injury and in particular it represent 12% of all death in man in comparison to 7% of dealt in female. This different in death rate is due to the different hormone levels between man and female. On the other hand female sex hormones, estrogens (e.g. 17b-estradiol) exert important biological actions, both protective and undesirable. In particular in addition to their primary function as reproductive hormones, estrogens (e.g. 17b-estradiol) influence a wide range of other physiological processes in humans and other mammals, including cardiovascular, respiratory, and neuronal function, and bone density.. With special respect to the cardiorespiratory system, estrogens promote lung development and differentiation and exhibit pulmonary and cardiovascular protective properties. However, very little is known about the different composition of the two major constituents of the connective tissue of the female and men lung. We have studied by CLSM the elastin an collagen in man and female lung. All proteins tested are present in lung tissue of male and female and they are localized in the peribronchiolar and in the interalveolar septum. The reaction to elastin shows very differences staining in the basal laminae of small and medium bronchioles in two sexes, in particular these structures stained very strongly in female but not in male. Opposite behavior we have showed to collagen type IV reactions. In male the collagen type IV is localized as a continuous network throughout the lung parenchymal tissue and in the basal laminae it shows strongly staining.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
title: ÐÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÑ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð°ÑÐ¾Ð¼Ð½Ð¾Ð¹ ÑÐ½ÐµÑÐ³Ð¸Ð¸, ÐºÐ°Ðº Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ð° Ð¿ÑÐ°Ð²Ð°
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÑÐ¸ÑÐ¸Ð½, ÐÐ»ÐµÐºÑÐµÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: Ð°ÑÐ¾Ð¼Ð½Ð°Ñ ÑÐ½ÐµÑÐ³Ð¸Ñ
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Ð»Ð¸ÑÐµÐ½Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸
nuclear energy
legal regulation
nuclear safety
radiation safety
licensing security

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÐµÑÑÑ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÑ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð°ÑÐ¾Ð¼Ð½Ð¾Ð¹ ÑÐ½ÐµÑÐ³Ð¸Ð¸, ÐºÐ°Ðº Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ð° Ð¿ÑÐ°Ð²Ð°, ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÑÑÑÑ ÑÐ°ÐºÐ¸Ðµ ÑÐ°Ð·Ð´ÐµÐ»Ñ ÐºÐ°Ðº Ð°ÑÐ¾Ð¼Ð½Ð°Ñ ÑÐ½ÐµÑÐ³Ð¸Ñ Ð¸ ÐµÑ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ðµ, ÑÐµÐ³ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð² ÑÑÐµÑÐµ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð°ÑÐ¾Ð¼Ð½Ð¾Ð¹ ÑÐ½ÐµÑÐ³Ð¸Ð¸, Ð²ÐºÐ»ÑÑÐ°Ñ, ÐºÐ°Ðº Ð·Ð°ÐºÐ¾Ð½Ð¾Ð´Ð°ÑÐµÐ»ÑÑÑÐ²Ð¾ Ð Ð¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð¹ Ð¤ÐµÐ´ÐµÑÐ°ÑÐ¸Ð¸, ÑÐ°Ðº Ð¸ Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½Ð¾Ðµ Ð¿ÑÐ°Ð²Ð¾ Ð² Ð´Ð°Ð½Ð½Ð¾Ð¹ Ð¾Ð±Ð»Ð°ÑÑÐ¸. Ð ÑÐ°Ð±Ð¾ÑÐµ Ð¸ÑÑÐ»ÐµÐ´ÑÐµÑÑÑ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ðµ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ Ð² ÑÑÐµÑÐµ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð°ÑÐ¾Ð¼Ð½Ð¾Ð¹ ÑÐ½ÐµÑÐ³Ð¸Ð¸, Ð¿ÑÐ°Ð²Ð¾Ð²Ð°Ñ Ð±Ð°Ð·Ð° Ð² ÑÑÐµÑÐµ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð°ÑÐ¾Ð¼Ð½Ð¾Ð¹ ÑÐ½ÐµÑÐ³Ð¸Ð¸, ÐºÑÐ¸ÑÐµÑÐ¸Ð¸ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ Ð¿ÑÐ¸ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð°ÑÐ¾Ð¼Ð½Ð¾Ð¹ ÑÐ½ÐµÑÐ³Ð¸Ð¸, ÑÐµÐ»Ð¸ Ð¸ ÑÑÐ½ÐºÑÐ¸Ð¸ Ð¸ Ð¿Ð¾Ð»Ð½Ð¾Ð¼Ð¾ÑÐ¸Ñ ÐÐÐÐÐ¢Ð­. Ð¢Ð°ÐºÐ¶Ðµ Ð² ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÑÑÑÑ Ð´Ð²Ð° Ð¿Ð¾Ð´ÑÐ°Ð·Ð´ÐµÐ»Ð°: 1) Ð Ð¾Ð»Ñ ÐÐÐÐÐ¢Ð­ Ð² Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ð¸ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾Ð³Ð¾ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð°ÑÐ¾Ð¼Ð½Ð¾Ð¹ ÑÐ½ÐµÑÐ³Ð¸Ð¸. 2)Ð¡Ð¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð·Ð°ÐºÐ¾Ð½Ð¾Ð´Ð°ÑÐµÐ»ÑÑÑÐ²Ð° Ð Ð¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð¹ Ð¤ÐµÐ´ÐµÑÐ°ÑÐ¸Ð¸ Ð² ÑÑÐµÑÐµ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð°ÑÐ¾Ð¼Ð½Ð¾Ð¹ ÑÐ½ÐµÑÐ³Ð¸Ð¸.
description: In this final qualification work safety of use of atomic energy as a problem is considered it is right, such sections as atomic energy and its use, regulation in the sphere of use of atomic energy are considered, including, both the legislation of the Russian Federation, and international law in the field. In work safety in the sphere of use of atomic energy, legal base in the sphere of use of atomic energy, criterion of safety is investigated when using atomic energy, the purpose and function and power of IAEA. Also in work two subsections are considered: 1) A role of IAEA in ensuring safe use of atomic energy. 2) Improvement of the legislation of the Russian Federation in the sphere of use of atomic energy.
Smentita la scoperta di materia oscura dal Sole
Creators: Francesca Scianitti
Publisher: name: Media Inaf
Year: 2015

Una ricerca pubblicata sulla rivista Monthly Notices of the Royal Astronomical Society smentisce il recente annuncio della scoperta degli assioni, particelle proposte come possibili candidati della materia oscura, emessi dalla nostra stella. Il nuovo studio è stato condotto congiuntamente da due ricercatori dell’Istituto Nazionale di Fisica Nucleare e dell’Istituto Nazionale di Astrofisica
Coupled Modulated Bilayers
Creators: name: Hirose, Yuichi
name: Komura, Shigeyuki
name: Andelman, David
Publisher: name: arXiv
Year: 2009
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We propose a model addressing the coupling mechanism between two spatially modulated monolayers. We obtain the mean-field phase diagrams of coupled bilayers when the two monolayers have the same preferred modulation wavelength. Various combinations of the monolayer modulated phases are obtained and their relative stability is calculated. Due to the coupling, a spatial modulation in one of the monolayers induces a similar periodic structure in the second one. We have also performed numerical simulations for the case when the two monolayers have different modulation wavelengths. Complex patterns may arise from the frustration between the two incommensurate but annealed structures.
description: 20 pages, 6 figures
Quel patatone di Giunone
Creators: Stefano Parisini
Publisher: name: Media Inaf
Year: 2015

Una serie di immagini ad alta risoluzione realizzate con il radiotelescopio ALMA dell'ESO in Cile forniscono una visione senza precedenti della superficie di Giunone, uno degli asteroidi più grandi della fascia principale situata tra le orbite di Marte e Giove
New Public Management In Higher Education - Exploring The Role Of Neo-Classic Vs. Public Value-Oriented Paradigms Of Leadership With Senior Executives Across 18 European Countries
Creators: name: Weißmüller, Kristina S.
Publisher: name: Universität Hamburg
Year: 2019
Subjects: Higher Education, Leadership, New Public Management, Public Value Orientation, Paradigm Shift

description: Institutions of Higher Education (HE) are subject to rapid and radical changes. Faced with rising socio-political demands, globalization and digitization of HE, public sector austerity, and conflicting strategic goals, HE leadership has become extremely challenging. In the wake of the fiscal crisis in 2008, top-level executive leaders in public HE are put under severe pressure to implement neo-classical cost-saving strategies that are alien to the traditional values of European academia. Consequently, HE institutions are moving away from traditional public value-oriented principles of collegial and value-oriented HE management (Public Value Orientation) toward a marketized, competition- and performance-oriented view on HE (New Public Management).

While the negative effects of this latent paradigm shift on academic staff is well researched, there is hardly any evidence on how top-level executives perceive and cope with this phenomenon. This master thesis closes this research gap by investigating whether HE leaders in Europe to-date are mainly driven by NPM-related values, it explores how prevalent politicized NPM-related value trade-offs are in the operative processes of HE leadership, and it reveals the detrimental consequences of the paradigm shift for European HE. Using an explorative and iterative mixed-methods approach, this thesis, first, derives research questions based on a systematic review of the scientific discourse on HE leadership and NPM to, second, conduct exploratory quantitative analyses on data of a unique survey conducted in 21 European countries with N = 7,312 top-level public sector executives, n = 631 of which are actively involved in (higher) education.

Results show that the paradigm shift toward marketized HE has created substantial conflict between the traditional values, identities, and goals of HE leaders and institutions by enforcing hierarchy, politicization, and a dysfunctional pressure toward short-term oriented criteria of economic productivity. NPM escalates the power of political stakeholders on HE who demand the implementation of policy reforms that are essentially obstructive to collaborative and innovative research and teaching HE leaders struggle severely to meet those ever-growing and value-incongruent demands without alienating themselves and their organizations from their core mission and the traditional values of academia.
Spatial correlation between submillimetre and Lyman-alpha galaxies in the SSA 22 protocluster
Creators: name: Tamura, Yoichi
name: Kohno, Kotaro
name: Nakanishi, Kouichiro
name: Hatsukade, Bunyo
name: Iono, Daisuke
name: Wilson, Grant W.
name: Yun, Min S.
name: Takata, Tadafumi
name: Matsuda, Yuichi
name: Tosaki, Tomoka
name: Ezawa, Hajime
name: Perera, Thushara A.
name: Scott, Kimberly S.
name: Austermann, Jason E.
name: Hughes, David H.
name: Aretxaga, Itziar
name: Chung, Aeree
name: Oshima, Tai
name: Yamaguchi, Nobuyuki
name: Tanaka, Kunihiko
name: Kawabe, Ryohei
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Lyman-alpha emitters are thought to be young, low-mass galaxies with ages of ~10^8 yr. An overdensity of them in one region of the sky (the SSA 22 field) traces out a filamentary structure in the early Universe at a redshift of z = 3.1 (equivalent to 15 per cent of the age of the Universe) and is believed to mark a forming protocluster. Galaxies that are bright at (sub)millimetre wavelengths are undergoing violent episodes of star formation, and there is evidence that they are preferentially associated with high-redshift radio galaxies, so the question of whether they are also associated with the most significant large-scale structure growing at high redshift (as outlined by Lyman-alpha emitters) naturally arises. Here we report an imaging survey of 1,100-um emission in the SSA 22 region. We find an enhancement of submillimetre galaxies near the core of the protocluster, and a large-scale correlation between the submillimetre galaxies and the low-mass Lyman-alpha emitters, suggesting synchronous formation of the two very different types of star-forming galaxy within the same structure at high redshift. These results are in general agreement with our understanding of the formation of cosmic structure.
description: Published in Nature (7th May 2009 issue). The astro-ph paper includes the main text (10 pages, 2 figures, 1 table) and supplementary material (6 pages, 4 figures, 1 table)
title: Ð ÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð¹ Ð²Ð½ÐµÑÐ½ÐµÐ¿Ð¾Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÐºÐ¾Ð½ÑÐµÐ¿ÑÐ¸Ð¸ ÐÐÐ Ð² ÐÐ·Ð¸Ð°ÑÑÐºÐ¾-Ð¢Ð¸Ñ Ð¾Ð¾ÐºÐµÐ°Ð½ÑÐºÐ¾Ð¼ ÑÐµÐ³Ð¸Ð¾Ð½Ðµ
title: Ð½Ð°ÑÑÐ½ÑÐ¹ Ð´Ð¾ÐºÐ»Ð°Ð´
titleType: Subtitle
Creators: name: ÐÑÐ¼Ð°Ð´ÐµÐµÐ²Ð°, Ð¯Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐµ Ð¾ÑÐ½Ð¾ÑÐµÐ½Ð¸Ñ
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Dynamic and structural properties of porcine serum albumins
Creators: name: Niramitranon, Jitti
name: Japrung, Deanpen
name: Boonmee, Apaporn
name: Koonawootrittriron, Skorn
name: Suwanasopee, Thanathip
name: Jattawa, Danai
name: Pongprayoon, Prapasiri
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Porcine serum albumin (PSA) is one of the promising biomarkers for pork detection. Pork contamination is a serious concern for the global halal food industry since many manufacturers mix pork into halal beef products to reduce production costs. Many studies have thus been devoted to designing effective PSA-detecting biosensors. PSA is closely related to Bovine serum albumin (BSA); therefore; the molecular insight into PSA characteristics becomes crucial to identify PSA. To understand PSA properties, Molecular dynamic (MD) simulations were employed. The three-dimensional structures of PSA were obtained from homology modelling and Alphafold. Both models give similar results. PSA seems to have high hydrophobicity and unique electrostatic properties. Unlike BSA, PSA has no large electropositive patch on the rear of domain III. This property can be used to differentiate PSA from BSA. In the case of drug sites, PSA provides comparable sizes of drug sites to those of canine serum albumin (CSA) which are larger than those of bovine, human and feline albumins. Such larger binding pockets can imply the ability of PSA to accommodate a broader spectrum of ligands. The findings here, especially the difference between BSA and PSA, can serve as a base to design effective biosensors to detect PSA contaminants.
Le stagioni del Sole
Creators: Marco Galliani
Publisher: name: Media Inaf
Year: 2015

La nostra stella è soggetta non solo ad un andamento ciclico undecennale, ma anche a una sorta di variabilità stagionale, assai più breve. Questa l'ipotesi avanzata da un team di ricercatori e pubblicata in un articolo sulla rivista Nature Communications. Il commento di Mauro Messerotti dell'INAF
Steps and control mechanisms of human dendritic cell differentiation
Creators: name: Romagnoli, Paolo
name: Silvano, Angela
name: Paccosi, Sara
name: Bonetti, Marida
name: Parenti, Astrid
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Cell culture; electron microscopy; immunofluorescence; Langerhans cells; monocytes; PPAR-gamma.

description: Among immune system dendritic cells (DCs), Langerhans cells (LCs) - found in stratified squamous epithelia - express langerin/CD207 and CD1a and contain Birbeck granules, while connective tissue DCs express DC-SIGN intensely. DCs may be generated in vitro from monocytes and from immature haematopoietic precursors; PPAR (peroxisome proliferator activated receptor)-gamma stimulation can direct CD133+ precursors to generate DCs with a LC phenotype [1]. In order to achieve deeper knowledge on human DC subtypes differentiation, circulating CD14+ monocytes have been isolated by immunomagnetic separation and cultured with GM-CSF, IL-4, and TGF-beta for 7 days. Maturation was induced by further culture for 48 h with TNF-alpha, IL-1 beta and IL-6 [2]. Rosiglitazone was used to stimulate PPARgamma. The cells were analysed by phase contrast and electron microscopy and by immunofluorescence. Both with and without rosiglitazone, cells with a dendritic shape were generated together with non-dendritic, elongated cells with the aspect of anti-inflammatory (M2) macrophages. All the generated, mature cells expressed MHC-II intensely. DCs grown with rosiglitazone were CD207-, while those grown without rosiglitazone appeared CD207+; in neither conditions did cells contain Birbeck granules, while in both conditions DCs expressed DC-SIGN, more intensely with than without rosiglitazone. Elongated non-dendritic cells expressed CD14 more intensely than DCs, and CD80, CD83 and CD86 as intensely as DCs. The results indicate that upon addiction of rosiglitazone the differentiation of cultured monocytes to LCs is hampered, at variance with what happens with cultures of CD133+ precursors. They also indicate that the generation of non-dendritic elongated cells, possibly M2 macrophages, can occur in association with that of dendritic cells.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
A systematic review of methods for quantitative evaluation of canal transportation: two-dimensional image methods
Creators: name: Kuralt, Marko
name: Fidler, Aleš
name: Tenyi, Ana
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Endodontics and Endodontology
subject: Dentistry
subject: FOS: Clinical medicine

description: A systematic review of methods for quantitative evaluation of canal transportation
Planetaristi d’Italia, unitevi
Creators: Gianluca Ranzini
Publisher: name: Media Inaf
Year: 2015

Negli spazi di Infini.to, accanto alla sede dell'INAF - Osservatorio Astrofisico di Torino: il XXX meeting PlanIt, il raduno degli explainer delle stelle organizzato dall'Associazione dei planetari italiani. Appuntamento a Pino Torinese dall'11 al 12 aprile