cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Anti-inflammatory activity of Avicennia germinans’ adventitious roots and first description of their metabolites
Creators: name: Dhaou, Dounia
name: Bousquet-Mélou, Anne
name: Mabrouki, Fathi
name: Di Giorgio, Carole
name: Bertolotti, Myriam
name: Herbette, Gaëtan
name: Baghdikian, Béatrice
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: This study investigated the anti-inflammatory and antioxidant activity of adventitious roots (AR) of Guyanese mangrove Avicennia germinans, used in folk traditional medicine (FTM). Using bio-guided fractionation, we searched for extracts with activities that can be used for therapeutic purposes. Our findings revealed an interesting anti-inflammatory activity of CH2Cl2 and EtOAc fractions from which eight compounds were isolated and identified by NMR: two naphtoquinone derivatives: avicennone C (1) and dehydro-α-lapachone (2), two triterpenes: β-betulinic acid (3) and betulinaldehyde (4), two phenylethanoid glycosides: trans-verbascoside (6) and isoverbascoside (8), one iridoid: geniposidic acid (5) and one naphtoquinone: rubinaphtin A (7). These compounds are described for the first time in the AR of A. germinans. Among them, 3 was the most active and abundant, suggesting that it mainly contributed to the fractions’ activity. This work reports the anti-inflammatory potential of A. germinans AR extracts for the first time and supports its use in FTM.
DS_10.1177_0022034520962455 – Supplemental material for Nonuniformity in Periodontal Ligament: Mechanics and Matrix Composition
Creators: name: B.K. Connizzo
name: L. Sun
name: N. Lacin
name: A. Gendelman
name: I. Solomonov
name: I. Sagi
name: A.J. Grodzinsky
name: G.R.S. Naveh
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, DS_10.1177_0022034520962455 for Nonuniformity in Periodontal Ligament: Mechanics and Matrix Composition by B.K. Connizzo, L. Sun, N. Lacin, A. Gendelman, I. Solomonov, I. Sagi, A.J. Grodzinsky and G.R.S. Naveh in Journal of Dental Research
sj-pdf-7-jhs-10.1177_1753193420914762 - Supplemental material for BSSH Spring Meeting Abstracts
Creators: name: Gough, Anthony
name: Owens, Ivy
name: Stone, Oliver
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-7-jhs-10.1177_1753193420914762 for BSSH Spring Meeting Abstracts by in Journal of Hand Surgery (European Volume)
Streamlined and green chromatographic approach for the determination of oxygen heterocyclic compounds in foodstuffs via miniaturised extraction
Creators: name: Irrera, Elisa
name: Cafeo, Giovanna
name: Russo, Marina
name: Calabrò, Maria Luisa
name: Mondello, Luigi
name: Dugo, Paola
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Plant Biology

description: A great number of plants, principally belonging to Apiaceae and Rutaceae families, contain oxygen heterocyclic compounds (OHCs), namely coumarins, furanocoumarins and polymethoxyflavones. Coumarin and its derivatives are widely exploited as therapeutic agents but also as flavouring agents in foods. Among all the OHCs, the content of coumarin is the only one strictly regulated in foods. The aim of this research was to investigate the amount of coumarin and other thirty-five OHCs in thirty foods flavoured with cinnamon, Citrus and carrot products to monitor the daily intake of OHCs by food. The primary objective of this study was to assess the potential for a greener approach to miniaturise the extraction procedure, thereby reducing the amount of solvents used and the time required. Liquid chromatography coupled with triple-quadrupole mass spectrometry detector was the approach of choice to determine the amount of OHCs in the samples of our interest.
sj-pdf-12-jhs-10.1177_1753193420914762 - Supplemental material for BSSH Spring Meeting Abstracts
Creators: name: Lu, Justin D.
name: Muskaan Sachdeva
name: Vender, Ronald
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-12-jhs-10.1177_1753193420914762 for BSSH Spring Meeting Abstracts by in Journal of Hand Surgery (European Volume)
sj-pdf-17-jhs-10.1177_1753193420914762 - Supplemental material for BSSH Spring Meeting Abstracts
Creators: name: Ryckie G. Wade
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-17-jhs-10.1177_1753193420914762 for BSSH Spring Meeting Abstracts by in Journal of Hand Surgery (European Volume)
Dynamics of oscillator populations globally coupled with distributed phase shifts
Creators: name: Smirnov, Lev A.
name: Pikovsky, Arkady
Publisher: name: arXiv
Year: 2023
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences

description: We consider a population of globally coupled oscillators in which phase shifts in the coupling are random. We show that in the maximally disordered case, where the pairwise shifts are i.i.d. random variables, the dynamics of a large population reduces to one without randomness in the shifts but with an effective coupling function, which is a convolution of the original coupling function with the distribution of the phase shifts. This result is valid for noisy oscillators and/or in presence of a distribution of natural frequencies. We argue also, using the property of global asymptotic stability, that this reduction is valid in a partially disordered case, where random phase shifts are attributed to the forced units only. However, the reduction to an effective coupling in the partially disordered noise-free situation may fail if the coupling function is complex enough to ensure the multistability of locked states.
sj-pdf-1-eso-10.1177_2396987320962911 - Supplemental material for Mind the Heart: Electrocardiography-gated cardiac computed tomography-angiography in acute ischaemic stroke—rationale and study design
Creators: name: Guglielmi, Valeria
name: Rinkel, Leon A
name: Nina-Suzanne Groeneveld
name: Lobé, Nick HJ
name: S Matthijs Boekholdt
name: Bouma, Berto J
name: Beenen, Ludo FM
name: Marquering, Henk A
name: Majoie, Charles BLM
name: Roos, Yvo BWEM
name: Randen, Adrienne Van
name: R Nils Planken
name: Coutinho, Jonathan M
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Cardiology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-eso-10.1177_2396987320962911 for Mind the Heart: Electrocardiography-gated cardiac computed tomography-angiography in acute ischaemic stroke—rationale and study design by Valeria Guglielmi, Leon A Rinkel, Nina-Suzanne Groeneveld, Nick HJ Lobé, S Matthijs Boekholdt, Berto J Bouma, Ludo FM Beenen, Henk A Marquering, Charles BLM Majoie, Yvo BWEM Roos, Adrienne van Randen, R Nils Planken and Jonathan M Coutinho in European Stroke Journal
Supplementary_material – Supplemental material for Arterial lactate as a prognostic tool to predict mortality and disposition in the emergency department: A prospective observational single-centre study
Creators: name: Wilson, William
name: Dhiraj Ravindran Selvaraj
name: MV Ramya Kumar
name: Vinayak Jain
name: Simran Umra
name: Murty, Shakuntala
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine

description: Supplemental material, Supplementary_material for Arterial lactate as a prognostic tool to predict mortality and disposition in the emergency department: A prospective observational single-centre study by William Wilson, Dhiraj Ravindran Selvaraj, MV Ramya Kumar, Vinayak Jain, Simran Umra and Shakuntala Murty in Hong Kong Journal of Emergency Medicine
Breathing Green: Maximising Health and Environmental Benefits for Active Transportation Users Leveraging Large Scale Air Quality Data
Creators: name: Yan, Sen
name: Zhu, Shaoshu
name: Fernandez, Jaime B.
name: Sánchez, Eric Arazo
name: Gu, Yingqi
name: O'Connor, Noel E.
name: O'Connor, David
name: Liu, Mingming
Publisher: name: arXiv
Year: 2023
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: Pollution in urban areas can have significant adverse effects on the health and well-being of citizens, with traffic-related air pollution being a major concern in many cities. Pollutants emitted by vehicles, such as nitrogen oxides, carbon monoxide, and particulate matter, can cause respiratory and cardiovascular problems, particularly for vulnerable road users like pedestrians and cyclists. Furthermore, recent research has indicated that individuals living in more polluted areas are at a greater risk of developing chronic illnesses such as asthma, allergies, and cancer. Addressing these problems is crucial to protecting public health and maximising environmental benefits. In this project, we explore the feasibility of tackling this challenge by leveraging big data analysis and data-driven methods. Specifically, we investigate the recently released Google Air Quality dataset and devise an optimisation strategy to suggest green travel routes for different types of active transportation users in Dublin. To demonstrate our achievement, we have developed a prototype and have shown that citizens who use our model to plan their outdoor activities can benefit notably, with a significant decrease of 17.87% on average in pollutant intake, from the environmental advantages it offers.
description: The manuscript has been accepted by the IEEE ITSC 2023
Additional file 3 of Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia
Creators: name: Pappalardo, Xena Giada
name: Risiglione, Pierpaolo
name: Zinghirino, Federica
name: Ostuni, Angela
name: Luciano, Daniela
name: Bisaccia, Faustino
name: De Pinto, Vito
name: Guarino, Francesca
name: Messina, Angela
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3: Figure. S3. Chromatin state and genomic features of VDAC1P5 gene from UCSC Genome Browser GRCh37/hg19. The genomic context of VDAC1P5 set around 1000 Kb upstream and downstream of the annotated Refseq is shown. The selected regulatory hub tracks are Pseudogene Annotation Set from GENCODE v.38lift37 Ensemble 104, Eukaryotic Promoter Database EPD v.4-6, CpG island track, Genotype-Tissue Expression GTEx RNA-seq v.8 2019, ChIP-Seq data for RNA polymerase II, H3K4me3 and H3K4me1, used as markers of transcriptional activation, H3K9me3 and H3K27me3 are markers of transcriptional repression, and chromatin state segmentation by Hidden Markov Model from the ENCODE/Broad project of nine different cell lines (GM12878, H1-hESC, HepG2, HMEC, HUVEC, K562, NHEK, NHLF) colored in grey to indicate the heterochromatin state.
Efficient InGaN-based Red Light-Emitting Diodes by Modulating Trench Defects
Creators: name: Pan, Z.
name: Chen, Z.
name: Zhang, H.
name: Yang, H.
name: Chen, Y.
name: Nie, J.
name: Deng, C.
name: Dong, B.
name: Wang, D.
name: Li, Y.
name: Lin, H.
name: Chen, W.
name: Jiao, F.
name: Kang, X.
name: Jia, C.
name: Liang, Z.
name: Wang, Q.
name: Zhang, G.
name: Shen, B.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Trench defects in multi-quantum wells (MQWs) have been considered as flawed structures that severely degrade the internal quantum efficiency of light-emitting diodes (LEDs) in the past. In this research, trench defects are innovatively modulated into the structure to enhance the efficiency of red InGaN LEDs. Specifically, dual-color MQWs structures are grown with green MQWs at the bottom and red MQWs at the top. When high-density trench defects are introduced into the green MQWs, the upper red MQWs exhibit a significant wavelength redshift of 68 nm and approximately 6-fold luminescence enhancement compared to those without trench defects. The wavelength redshift is attributed to the increased indium incorporation due to the strain relaxation effect of trench defects. Moreover, the luminescence enhancement originates from the strong emission of the red MQWs inside trench defects. The mechanisms behind the superior luminescent properties of red MQWs within trench defects are explored in detail. Red InGaN LEDs with an internal quantum efficiency of 16.4% are achieved by modulating the trench defects. The method of achieving InGaN-based red emission by introducing trench defects is simple and reproducible, requiring no additional substrate designs. This research provides a novel pathway toward achieving high-efficiency red InGaN LEDs.
Supplemental Material, sj-pdf-1-jgp-10.1177_0891988720964250 - Sleep Problems Are Related to a Worse Quality of Life and a Greater Non-Motor Symptoms Burden in Parkinson’s Disease
Creators: name: Santos-García, Diego
name: Castro, E. Suárez
name: de Deus Fonticoba, T.
name: Panceiras, M. J. Feal
name: Enriquez, J. G. Muñoz
name: González, J. M. Paz
name: Bartolomé, C. Cores
name: Planellas, L. L.
name: Caldentey, J. García
name: Caballol, N.
name: Legarda, I.
name: López, I. Cabo
name: Manzanares, L. López
name: Rivera, M. A. Ávila
name: Catalán, M. J.
name: Nogueira, V.
name: Borrué, C.
name: Sauco, M. Álvarez
name: Vela, L.
name: Cubo, E.
name: Castrillo, J. C. Martínez
name: Alonso, P. Sánchez
name: Losada, M. G. Alonso
name: Ariztegui, N. López
name: Gastón, M. I.
name: Kulisevsky, J.
name: Pagonabarraga, J.
name: Seijo, M.
name: Martínez, J. Ruíz
name: Valero, C.
name: Kurtis, M.
name: Ardura, J. González
name: Prieto, C.
name: Mir, P.
name: Martinez-Martin, P.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental Material, sj-pdf-1-jgp-10.1177_0891988720964250 for Sleep Problems Are Related to a Worse Quality of Life and a Greater Non-Motor Symptoms Burden in Parkinson’s Disease by Diego Santos-García, E. Suárez Castro, T. de Deus Fonticoba, M. J. Feal Panceiras, J. G. Muñoz Enriquez, J. M. Paz González, C. Cores Bartolomé, L. L. Planellas, J. García Caldentey, N. Caballol, I. Legarda, I. Cabo López, L. López Manzanares, M. A. Ávila Rivera, M. J. Catalán, V. Nogueira, C. Borrué, M. Álvarez Sauco, L. Vela, E. Cubo, J. C. Martínez Castrillo, P. Sánchez Alonso, M. G. Alonso Losada, N. López Ariztegui, M. I. Gastón, J. Kulisevsky, J. Pagonabarraga, M. Seijo, J. Ruíz Martínez, C. Valero, M. Kurtis, J. González Ardura, C. Prieto, P. Mir, P. Martinez-Martin and on behalf of the COPPADIS Study Group in Journal of Geriatric Psychiatry and Neurology
A new seco-iridoid glycoside from fruits of Cornus officinalis Sieb. et Zucc and their neuroprotective activities
Creators: name: Yang, Meng
name: Hao, Zhi-You
name: Wang, Xiao-Lan
name: Zhou, Shi-Qi
name: Xiao, Chao-Yuan
name: Zheng, Xiao-Ke
name: Feng, Wei-Sheng
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: A new seco-iridoid glycoside, named neocornuside I (1), together with seven previously reported compounds (2–8) were isolated from fruits of Cornus officinalis Sieb. et Zucc. Their structures were determined by extensive analysis of HRESIMS, IR, UV, 1D and 2D NMR spectral data. The isolated compounds (1–8) were evaluated for their in vitro neuroprotective activities. Based on flow cytometry results, compound 1 was found to alleviate apoptosis and G2/M phase arrest, indicating its considerable neuroprotective effects.
3185449246636_EvoBioRevSupplTable1_xyz466364bc83175 – Supplemental material for Vesicle Transport in Plants: A Revised Phylogeny of SNARE Proteins
Creators: name: Xiaoyan Gu
name: Brennan, Adrian
name: Wenbin Wei
name: Guangqin Guo
name: Lindsey, Keith
Publisher: name: SAGE Journals
Year: 2020
Subjects: Cell Biology

description: Supplemental material, 3185449246636_EvoBioRevSupplTable1_xyz466364bc83175 for Vesicle Transport in Plants: A Revised Phylogeny of SNARE Proteins by Xiaoyan Gu, Adrian Brennan, Wenbin Wei, Guangqin Guo and Keith Lindsey in Evolutionary Bioinformatics
Additional file 1 of Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia
Creators: name: Pappalardo, Xena Giada
name: Risiglione, Pierpaolo
name: Zinghirino, Federica
name: Ostuni, Angela
name: Luciano, Daniela
name: Bisaccia, Faustino
name: De Pinto, Vito
name: Guarino, Francesca
name: Messina, Angela
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure. S1a, b Summary of annotated transcripts for the VDAC1P8 pseudogene from GENCODE v.39 Ensembl 105. In (a) the table reports gene annotations of 14 transcripts for VDAC1P8 reported on Ensembl database release 105. In (b) the screenshot modified by GENCODE v.39 illustrates some main structural and regulatory features of the variants' alignment.
Investigating the Use of Dialogue in the Construction of Scientific Understanding in the Junior Primary Classroom
Creators: name: France, Ann Rebecca
Publisher: name: Figshare
Year: 2017
Subjects: Education

description: There
has been increased recognition of the importance of dialogue in science
learning over the past decades, linked with a greater use of dialogue as a
pedagogical tool in teaching science (Mercer & Dawes, 2014). Arguments
centre on a predictive prevalence in students developing higher level thinking
when dialogue is used effectively. However, evidence suggests that many primary
school teachers lack the knowledge and skills to promote effective dialogue
that produces higher level thinking in their students. To investigate this
problem, this case study examined the use of dialogue in the development of
scientific thinking and understanding in the junior primary classroom of an
inner city, Catholic, primary school in Melbourne, Australia. The specific
purpose of the study was to identify how four junior primary teachers’
perceived dialogue when implementing deep-level learning in their science
classrooms and to record their dialogic patterns with their students. The study
utilised a purposive sampling technique to invite teachers who had participated
in professional development on scientific literacy to take part in the study.
In-depth interviews were conducted with four teachers and three classroom
observations of up to six students were recorded in each class, resulting in 12
observations altogether. A talk analysis framework using existing literature on
effective classroom talk was developed and applied to classroom observations to
identify dialogic patterns. The data analysis identified three key findings.
The first relates to teachers’ beliefs about dialogue and the development of
scientific understanding; the second relates to dialogue as a process that
supports deep thinking, and the last relates to the central role of the teacher
as a dialogue facilitator. These findings suggest the need to increase
teachers’ professional development and awareness of the importance of dialogue
in deep-level teaching and learning in science lessons.
Quantitative Maximal Diameter Rigidity of Positive Ricci Curvature
Creators: name: Ren, Tianyin
name: Rong, Xiaochun
Publisher: name: arXiv
Year: 2023
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: In Riemannian geometry, the Cheng's maximal diameter rigidity theorem says that if a complete $n$-manifold $M$ of Ricci curvature, $\operatorname{Ric}_M\ge (n-1)$, has the maximal diameter $π$, then $M$ is isometric to the unit sphere $S^n_1$. The main result in this paper is a quantitative maximal diameter rigidity: if $M$ satisfies that $\operatorname{Ric}_M\ge n-1$, $\operatorname{diam}(M)\approx π$, and the Riemannian universal cover of every metric ball in $M$ of a definite radius satisfies a Riefenberg condition, then $M$ is diffeomorphic and bi-Hölder close to $S^n_1$.
Secondary metabolites of Silene claviformis Litv. and the anti-inflammatory activity of its butanol extract
Creators: name: Khurramov, Alisher
name: Yusupova, Ugiloy
name: Bobakulov, Khayrulla
name: Syrov, Vladimir
name: Egamova, Feruza
name: Usmanov, Durbek
name: Quadir, Mohiuddin
name: Rasulev, Bakhtiyor
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: In this study, we present the result of chemical investigation of aerial parts of Silene claviformis Litv., where we isolated four known natural secondary metabolites: two triterpenoids cycloastragenol (1), astrasieversianin X(2), as well as two steroid glycosides lineolon (3), 3-O-acetate sibirgenin (4), for the first time for this plant. The compound 4 was isolated from this plant for the first time as a natural substance. The chemical structures of these compounds were determined through comprehensive spectroscopic analyses, including 1D and 2D NMR spectroscopy, LC-MS, and comparison with previously reported data. Furthermore, the butanol fraction was evaluated for its anti-inflammatory and antiexudative activities. Upon administration of silver nitrate, exudation into the pleural and abdominal cavities was reduced by 21.8% and 22.6%, respectively. The fraction also inhibited the exudative phase of inflammation in rats, significantly reducing paw swelling induced by formaldehyde and serotonin. Additionally, it decreased vascular permeability in rabbits exposed to xylene, highlighting its potential as an anti-inflammatory agent.
Floquet systems with continuous dynamical symmetries: characterization, time-dependent Noether charge, and solvability
Creators: name: Kaneko, Yukio
name: Ikeda, Tatsuhiko N.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study quantum Floquet (periodically-driven) systems having continuous dynamical symmetry (CDS) consisting of a time translation and a unitary transformation on the Hilbert space. Unlike the discrete ones, the CDS strongly constrains the possible Hamiltonians $H(t)$ and allows us to obtain all the Floquet states by solving a finite-dimensional eigenvalue problem. Besides, Noether's theorem leads to a time-dependent conservation charge, whose expectation value is time-independent throughout evolution. We exemplify these consequences of CDS in the seminal Rabi model, an effective model of a nitrogen-vacancy center in diamonds without strain terms, and Heisenberg spin models in rotating fields. Our results provide a systematic way of solving for Floquet states and explain how they avoid hybridization in quasienergy diagrams.
description: 15+4 pages, 4 figures, v3 minor revisions and some improvements
HEB-19-0568_-_Supplementary_file – Supplemental material for Influence of Maternal Exposure to Malaria Social and Behavioral Change Messages and Effectiveness of Communication Media on Bed Net Use and Malaria Infection in Malawi
Creators: name: Nkoka, Owen
name: Ting-Wu Chuang
name: Chen, Yi-Hua
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, HEB-19-0568_-_Supplementary_file for Influence of Maternal Exposure to Malaria Social and Behavioral Change Messages and Effectiveness of Communication Media on Bed Net Use and Malaria Infection in Malawi by Owen Nkoka, Ting-Wu Chuang and Yi-Hua Chen in Health Education & Behavior
Supplemental Material, supplement_-_sites - Characteristics and Outcomes of Patients With Diabetes Mellitus Undergoing Peripheral Vascular Intervention for Infrainguinal Symptomatic Peripheral Artery Disease
Creators: name: E. Hope Weissler
name: Narcisse, Dennis I.
name: Rymer, Jennifer A.
name: Ehrin J. Armstrong
name: Secemsky, Eric
name: Gray, William A.
name: Mustapha, Jihad A.
name: Adams, George L.
name: Ansel, Gary M.
name: Manesh R. Patel
name: W. Schuyler Jones
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Cardiology
subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental Material, supplement_-_sites for Characteristics and Outcomes of Patients With Diabetes Mellitus Undergoing Peripheral Vascular Intervention for Infrainguinal Symptomatic Peripheral Artery Disease by E. Hope Weissler, Dennis I. Narcisse, Jennifer A. Rymer, Ehrin J. Armstrong, Eric Secemsky, William A. Gray, Jihad A. Mustapha, George L. Adams, Gary M. Ansel, Manesh R. Patel and W. Schuyler Jones in Vascular and Endovascular Surgery
Supplemental Material, Appendix_CareCoordination_5.15.2020 - Evaluation of a Care Management Program for Pediatric Epilepsy Patients
Creators: name: Min, Jea Young
name: Anup D. Patel
name: Glynn, Peter
name: Munkhzul Otgonsuren
name: Babitha Harridas
name: Grinspan, Zachary M.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111403 Paediatrics
subject: Neuroscience

description: Supplemental Material, Appendix_CareCoordination_5.15.2020 for Evaluation of a Care Management Program for Pediatric Epilepsy Patients by Jea Young Min, Anup D. Patel, Peter Glynn, Munkhzul Otgonsuren, Babitha Harridas and Zachary M. Grinspan in Journal of Child Neurology
Neuroprotective activities of coixol: in vitro and in silico studies
Creators: name: Amen, Yhiya
name: Othman, Ahmed
name: Sayed, Ahmed M.
name: El-Damasy, Ashraf K.
name: Mira, Amira
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Biophysics
Biochemistry
Cell Biology
Neuroscience
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: This study explored coixol, a natural compound from Coix lacryma-jobi, as a potential neuroprotective agent. Coixol’s efficacy was assessed through in vitro assays, molecular docking, and molecular dynamics (MD) simulations, focusing on its effects on acetylcholinesterase (AChE) activity, oxidative stress, and Aβ1-42 protofibril interactions. Coixol inhibited AChE with an IC50 value of 3.63 ± 1.2 µM and stably interacted with its active site, mimicking tacrine, a known AChE inhibitor. It also protected SH-SY5Y cells against H2O2 and Aβ1-42-induced neurotoxicity in a dose-dependent manner. Gaussian accelerated MD (GaMD) simulations revealed two stable binding modes of coixol with Aβ1-42 protofibrils. One mode significantly disrupted the protofibril’s structural integrity, explaining coixol’s protective effects. These results highlight coixol’s multi-target therapeutic potential in modulating AChE activity, reducing oxidative stress, and inhibiting Aβ aggregation, offering promising opportunities for neuroprotective drug development.
Additional file 2: of Examining the relationship between therapeutic self-care and adverse events for home care clients in Ontario, Canada: a retrospective cohort study
Creators: name: Sun, Winnie
name: Doran, Diane
name: Wodchis, Walter
name: Peter, Elizabeth
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy

description: Therapeutic self-care scale - Home Care. (DOC 22Â kb)
Table_S1 – Supplemental material for Minocycline as adjunctive treatment for major depressive disorder: Pooled data from two randomized controlled trials
Creators: name: Zazula, Robson
name: Husain, Muhammad Ishrat
name: Mohebbi, Mohammadreza
name: Walker, Adam J
name: Chaudhry, Imran B
name: Khoso, Ameer B
name: Ashton, Melanie M
name: Agustini, Bruno
name: Husain, Nusrat
name: Deakin, JFW
name: Young, Allan H
name: Berk, Michael
name: Kanchanatawan, Buranee
name: Ng, Chee H
name: Maes, Michael
name: Berk, Lesley
name: Singh, Ajeet B
name: Malhi, Gin S
name: Dean, Olivia M
Publisher: name: SAGE Journals
Year: 2020
Subjects: Psychology not elsewhere classified
Psychiatry (incl. Psychotherapy)
Neuroscience

description: Supplemental material, Table_S1 for Minocycline as adjunctive treatment for major depressive disorder: Pooled data from two randomized controlled trials by Robson Zazula, Muhammad Ishrat Husain, Mohammadreza Mohebbi, Adam J Walker, Imran B Chaudhry, Ameer B Khoso, Melanie M Ashton, Bruno Agustini, Nusrat Husain, JFW Deakin, Allan H Young, Michael Berk, Buranee Kanchanatawan, Chee H Ng, Michael Maes, Lesley Berk, Ajeet B Singh, Gin S Malhi and Olivia M Dean in Australian & New Zealand Journal of Psychiatry
Table_S2 – Supplemental material for Minocycline as adjunctive treatment for major depressive disorder: Pooled data from two randomized controlled trials
Creators: name: Zazula, Robson
name: Husain, Muhammad Ishrat
name: Mohebbi, Mohammadreza
name: Walker, Adam J
name: Chaudhry, Imran B
name: Khoso, Ameer B
name: Ashton, Melanie M
name: Agustini, Bruno
name: Husain, Nusrat
name: Deakin, JFW
name: Young, Allan H
name: Berk, Michael
name: Kanchanatawan, Buranee
name: Ng, Chee H
name: Maes, Michael
name: Berk, Lesley
name: Singh, Ajeet B
name: Malhi, Gin S
name: Dean, Olivia M
Publisher: name: SAGE Journals
Year: 2020
Subjects: Psychology not elsewhere classified
Psychiatry (incl. Psychotherapy)
Neuroscience

description: Supplemental material, Table_S2 for Minocycline as adjunctive treatment for major depressive disorder: Pooled data from two randomized controlled trials by Robson Zazula, Muhammad Ishrat Husain, Mohammadreza Mohebbi, Adam J Walker, Imran B Chaudhry, Ameer B Khoso, Melanie M Ashton, Bruno Agustini, Nusrat Husain, JFW Deakin, Allan H Young, Michael Berk, Buranee Kanchanatawan, Chee H Ng, Michael Maes, Lesley Berk, Ajeet B Singh, Gin S Malhi and Olivia M Dean in Australian & New Zealand Journal of Psychiatry
Isolation and purification of sinensetin, and in silico screening of phytochemicals from Orthosiphon aristatus (Blume) Miq. for anti-breast cancer activity
Creators: name: Nguyen, Phuong Tram
name: Huynh, Quoc-Dung Tran
name: Nguyen, Minh Duc
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Orthosiphon aristatus (Blume) Miq. (O. aristatus), a traditional herbal medicine, exhibits a wide range of biological activities but its anti-breast cancer effect is not fully established. In this study, sinensetin was isolated and purified through a multistep process, beginning with liquid-liquid partitioning using dichloromethane, followed by classic column chromatography using gradient elution. Preparative high-performance liquid chromatography with acetonitrile-water (41:59, v/v) mobile phase successfully isolated sinensetin to 95% purity. In silico screening of O. aristatus-derived bioactive compounds revealed that flavonoids (including sinensetin), polyphenols (i.e. 2,3-O-dicaffeoyltartaric acid, rosmarinic acid), diterpenoid (i.e. trans-ozic acid), triterpenoids and dipeptide (i.e. aurantiamide acetate) have good binding affinities with 17β-HSD1, ErbB2/HER2 and PI3K-PKB/Akt proteins. These findings suggest that O. arsistatus could be a rich natural source of inhibitors targeting molecular pathways involved in breast cancer, offering promising therapeutic benefits.
Characterisation of microbial fructosyltransferase produced extracellularly from Bacillus siamensis GO6 for prebiotic production
Creators: name: Gautam, Neha
name: Puneet
name: Sharma, Nivedita
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The present study aimed to characterise bacterial Fructosyltransferase (FTase; EC 2.4.1.9) from Bacillus siamensis GO6 isolated from Allium fistulosum. The FTase producing potential of B. siamensis is being reported for the first time in this study. Fructosyltransferase production of B. siamensis GO6 was enhanced by optimisation of growth parameters. Maximum Fructosyltransferase activity 134.75 U/ml was recorded in nutrient broth supplemented with tryptone, 60% sucrose at 72 h with an optimised pH of 6.0 at 40 °C. Partial purification of FTase was achieved at 30–60%. FTase titres after partial purification were 175 U/ml with specific activity 484.76 U/mg, and 77% recovery. Partially purified FTase was active in a temperature range 30 °C and 80 °C and in pH 5.0 to 9.0. FTase was found stable at −20 °C for 45 days. The results showed that the B. siamensis GO6 represents a hopeful source for FTase enzyme that can be efficiently utilised for prebiotic production.
Design-Informed Generative Modelling using Structural Optimization
Creators: name: Sarma, Lowhikan Sivanantha
name: Mallikarachchi, Chinthaka
name: Herath, Sumudu
Publisher: name: arXiv
Year: 2023
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: Although various structural optimization techniques have a sound mathematical basis, the practical constructability of optimal designs poses a great challenge in the manufacturing stage. Currently, there is only a limited number of unified frameworks which output ready-to-manufacture parametric Computer-Aided Designs (CAD) of the optimal designs. From a generative design perspective, it is essential to have a single platform that outputs a structurally optimized CAD model because CAD models are an integral part of most industrial product development and manufacturing stages. This study focuses on developing a novel unified workflow handling topology, layout and size optimization in a single parametric platform, which subsequently outputs a ready-to-manufacture CAD model. All such outputs are checked and validated for structural requirements; strength, stiffness and stability in accordance with standard codes of practice. In the proposed method, first, topology-optimal model is generated and converted to a one-pixel-wide chain model using skeletonization. Secondly, a spatial frame is extracted from the skeleton for its member size and layout optimization. Finally, the CAD model is generated using constructive solid geometry trees and the structural integrity of each member is assessed to ensure structural robustness prior to manufacturing. Various examples presented in the paper showcase the validity of the proposed method across various engineering disciplines.
Deterministic active particles in the overactive limit
Creators: name: Pikovsky, Arkady
Publisher: name: arXiv
Year: 2023
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We consider two models of deterministic active particles in an external potential. In the limit where the speed of a particle is fixed, both models coincide and can be formulated as a Hamiltonian system, but only if the potential is time-independent. If the particles are identical, their interaction via a potential force leads to conservative dynamics with a conserved phase volume. In contrast, the phase volume is shown to shrink for non-identical particles.
Is the glassy dynamics same in 2D as in 3D? The Adam Gibbs relation test
Creators: name: Nath, Santu
name: Sengupta, Shiladitya
Publisher: name: arXiv
Year: 2023
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: It has been recognized of late that even amorphous, glass-forming materials in two dimensions (2D) are significantly affected by Mermin-Wagner type long wavelength thermal fluctuation which is inconsequential in three (3D) and higher dimensions. Thus any study of glassy dynamics in 2D should first remove the effect of such fluctuations. The present work considers the question of whether the role of spatial dimension on glassy dynamics is only limited to such fluctuations, or whether the nature of glassy dynamics is intrinsically different in 2D. We address this issue by studying the relationship between dynamics and thermodynamics within the framework of the Adam-Gibbs (AG) relation and its generalization the Random First Order Transition (RFOT) theory. Using two model glass-forming liquids we find that even after removing the effect of long wavelength fluctuations, the AG relation breaks down in two dimensions. Then we consider the effect of anharmonicity of vibrational entropy - a second factor highlighted recently that can qualitatively change the nature of dynamics. We explicitly compute the configurational entropy both with and without the anharmonic correction. We show that the anharmonic correction reduces the extent of deviation from the AG relation, but even after taking into account its effects, the AG relation still breaks down in 2D. It is also more prominent if one considers diffusion coefficient rather than $α$-relaxation time. Overall, the impact of the anharmonicity of vibration is larger than the long wavelength fluctuation in determining the qualitative relation between timescales and entropy. The extent and nature of deviation from the AG relation crucially depends on the attractive vs. repulsive nature of the inter-particle interaction. Thus our results suggest that the glassy dynamics in 2D may be intrinsically different from that in 3D.
A new coumarin from Tridax procumbens L. as potential anticancer, antibacterial, antioxidant agent and its molecular docking study
Creators: name: Ingole, Varsharani V.
name: Mhaske, Pravin C.
name: Shaikh, Siraj B.
name: Katade, Sushma R.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: A study investigated the phytochemical constituent of the methanol extract from the aerial part of T. procumbens L. The investigation resulted in the identification of a new coumarin. A novel coumarin compound was successfully isolated using the silica gel column chromatographic technique and various spectroscopic methods were employed to elucidate its structure. Isolated new coumarin was evaluated for its cytotoxicity, antimicrobial, and antioxidant activities. The isolated coumarin exhibited cytotoxicity IC50 values of 4.92 and 5.99 µg/mL against MCF-7 and MDA-MB-249 cell lines, respectively, in the MTT assay. Additionally, the compound demonstrated notable antioxidant activity, with an IC50 value of 1.36 µg/mL (p < 0.05). The antimicrobial evaluation revealed MIC values of 125 µg/mL against S. aureus and 31.5 µg/mL against P. aeruginosa. This activity is strongly supported by an in silico study. Further studies are required to determine its effectiveness as an antioxidant, anticancer, and antibacterial agent.
UKSG 2022: Research Catalyst: situating the Archive and library staff at the centre of the research process
Creators: name: Bullingham, Liam
name: Franca, Anna
Publisher: name: Edge Hill University
Year: 2022
Subjects: Library and information studies not elsewhere classified
Humanities and social sciences curriculum and pedagogy (excl. economics, business and management)

description: Abstract Challenges posed by COVID-19 have highlighted the importance of collaboration between libraries, archives, and academics. At Edge Hill University we have established ‘Research Catalyst’, a research group aiming to advance the productive and positive relationship between colleagues in Library and Learning Services (LSS) and the Department of History, English and Creative Writing, and positioning LSS as a co-lead in the research process with the potential of co-supervising or leading research projects.
 We have established a Memorandum of Understanding defining the purpose of our group and reflecting the complimentary agendas of librarians and academics. This talk introduces Research Catalyst and our ambitions for the future.
Effect of Grain Coalescence on Dislocation and Stress Evolution of GaN Films Grown on Nanoscale Patterned Sapphire Substrates
Creators: name: Pan, Zuojian
name: Chen, Zhizhong
name: Chen, Yiyong
name: Zhang, Haodong
name: Yang, Han
name: Nie, Jingxin
name: Deng, Chuhan
name: Dong, Boyan
name: Wang, Daqi
name: Li, Yuchen
name: Chen, Weihua
name: Jiao, Fei
name: Kang, Xiangning
name: Jia, Chuanyu
name: Liang, Zhiwen
name: Wang, Qi
name: Zhang, Guoyi
name: Shen, Bo
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Two types of nucleation layers (NLs), including in-situ low-temperature grown GaN (LT-GaN) and ex-situ sputtered physical vapor deposition AlN (PVD-AlN), are applied on cone-shaped nanoscale patterned sapphire substrate (NPSS). The initial growth process of GaN on these two NLs is comparably investigated by a series of growth interruptions. The coalescence process of GaN grains is modulated by adjusting the three-dimensional (3D) temperatures. The results indicate that higher 3D temperatures reduce the edge dislocation density while increasing the residual compressive stress in GaN films. Compared to the LT-GaN NLs, the PVD-AlN NLs effectively resist Ostwald ripening and facilitate the uniform growth of GaN grains on NPSS. Furthermore, GaN films grown on NPSS with PVD-AlN NLs exhibit a reduction of over 50% in both screw and edge dislocation densities compared to those grown on LT-GaN NLs. Additionally, PVD-AlN NLs result in an increase of about 0.5 GPa in the residual compressive stress observed in GaN films.
INFLUENCE OF ALKYLATED NAPHTENIC ACID AMIDE CONTAINING BIOCIDE COMPOSITIONS OF BAKU CRUDE OIL ON SULPHATE REDUCING BACTERIA
Creators: name: Abbasov, V. М.
name: Ezizbeyli, A. R.
name: Jafarova, R. A.
name: Ahmedbekova, S. A.
name: Agamalieva, D. B.
Publisher: name: European Chemical Bulletin
Year: 2014

description: Compounds formed in the reaction of napthenic acid amides of Baku crude oil with some of the alkyl halogenides are found to be multi-functional corrosion inhibitors. The structural features of compounds were studies with FT-IR spectroscopy. The efficiency of these inhibitors have also been tested against sulphate reducing bacteria (SRB) at a temperature of 30 oC for  and for a period of 15 days time.
description: European Chemical Bulletin, Vol 3, No 9 (2014): European Chemical Bulletin
A comparative MSD-SPME-GC/mS analysis of two Artemisia species from the Rhaetian alps (Italy)
Creators: name: Özek, Gulmira
name: Shukurlu, Emil N.
name: Özek, Temel
name: Bertolini, Cristina
name: Iriti, Marcello
name: Pezzani, Raffaele
name: Vitalini, Sara
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Plants of the Artemisia genus (Asteraceae) are integral to the cultural heritage of Alpine communities, where they are used in herbal infusions and alcoholic beverages. This study analysed the volatile composition of A. genipi Weber and A. umbelliformis Lam. from the Central Alps using microsteam distillation (MSD) combined with solid-phase microextraction (SPME) to identify compounds influencing their flavour. Chemical analysis revealed distinct profiles, with A. genipi showing a higher proportion of monoterpene hydrocarbons (32.8%) than A. umbelliformis (5.6%), whereas A. umbelliformis contained more oxygenated monoterpenes (85.3% vs. 43.9%), including α-thujone (56.9% and 32.2%, respectively) and β-thujone (11.6% and 4.6%), classifying both as part of the thujone chemotype. Compounds like cis-2-methyl-3-methylene-5-heptene (0.5%) and methyl-(E)-eremophila-1(10),7(11)-dien-12-oate (1.1%) were found for the first time in the Artemisia genus. The findings underscore the need for further research to unravel the full extent of chemical and biological diversity between the two species.