cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
POSSIBILITIES OF USING TRANSPLANTATION OF AUTOLOGICAL ADITY TISSUE ENRICHED IN STEM CELLS IN MAMMOPlasty.
Creators: name: Abduaxatov, Abdulaziz
name: Razokov, Baxodir
name: Maxmudov, Begzod
Publisher: name: Zenodo
Year: 2024

description: Every year, the number of cases of mammoplasty performed for cosmetic reasons increases.  However, operations on the mammary glands (MG) are often performed not only for aesthetic reasons.  The trend of increasing incidence of breast cancer (BC) in women continues [1–3].  Among the technologies for combined treatment of patients with breast cancer, the surgical method remains fundamental.  Moreover, both radical mastectomy and partial resections of gl.mammae after surgery are invariably accompanied by the formation of breast deformities.  The latter causes a deterioration in the quality of life of women with breast cancer, reducing the possibility of their rapid social adaptation [4].
title: Anomalies and Anatomic variants of middle cerebral artery: What the radiologist needs to know
Creators: name: Orciulo, Grazia Vittoria
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Neuroradiology brain
subject: Catheter arteriography
subject: MR-Angiography
subject: Diagnostic procedure
subject: Congenital

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Middle cerebral artery (MCA) anomalies occur less frequently than other major intracranial arteries anomalies. Their knowledge is helpful to surgeons and clinicians because MCA provides to the vascularization of important brain’s areas, such as...
Co-Clinical Trials Demonstrate Superiority of Crizotinib to Chemotherapy in ALK-Rearranged Non-Small Cell Lung Cancer and Predict Strategies to Overcome Resistance
Creators: name: Engelman, Jeffrey A.
name: Tupper, Tanya
name: Chen, Liang
name: Kung, Andrew L.
name: Wong, Kwok Kin
name: Cheng, Katherine
name: Akbay, Esra
name: Janne, Pasi A.
name: Woo, Sue Ann
name: Altabef, Abigail
name: Reibel, Jacob B.
name: Mikse, Oliver
name: Wang, Yuchuan
name: Shapiro, Geoffrey I.
name: Sharpless, Norman E.
name: Chen, Zhao
name: Tan, Xiaohong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: To extend the results of a phase III trial in non-small cell lung cancer patients with adenocarcinomas harboring EML4-ALK fusion.
(401256) James Hall Sleigh
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Thermodynamically consistent continuum dislocation dynamics
Creators: name: Hochrainer, Thomas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Dislocation based modeling of plasticity is one of the central challenges at the crossover of materials science and continuum mechanics. Developing a continuum theory of dislocations requires the solution of two long standing problems: (i) to represent dislocation kinematics in terms of a reasonable number of variables and (ii) to derive averaged descriptions of the dislocation dynamics (i.e. material laws) in terms of these variables. The kinematic problem (i) was recently solved through the introduction of continuum dislocation dynamics (CDD), which provides kinematically consistent evolution equations of dislocation alignment tensors, presuming a given average dislocation velocity (Hochrainer (2015), Philos. Mag. 95 (12), 1321--1367). In the current paper we demonstrate how a free energy formulation may be used to solve the dynamic closure problem (ii) in CDD. We do so exemplarily for the lowest order CDD variant for curved dislocations in a single slip situation. In this case, a thermodynamically consistent average dislocation velocity is found to comprise five mesoscopic shear stress contributions. For a postulated free energy expression we identify among these stress contributions a back-stress term and a line-tension term, both of which have already been postulated for CDD. A new stress contribution occurs which is missing in earlier CDD models including the statistical continuum theory of straight parallel edge dislocations (Groma et al. (2015), Acta Mater. 51, 1271-1281). Furthermore, two entirely new stress contributions arise from the curvature of dislocations.
Effects of Tumor Microenvironment Heterogeneity on Nanoparticle Disposition and Efficacy in Breast Cancer Tumor Models
Creators: name: Ross, Mark
name: Santos, Charlene M.
name: Midkiff, Bentley R.
name: Zamboni, William C.
name: Perou, Charles M.
name: Miller, C. Ryan
name: Nikolaishvili-Feinberg, Nana
name: Rogers, Arlin B.
name: Cohen, Stephanie
name: Valdivia, Alain
name: Darr, David B.
name: Dudley, Andrew C.
name: Jordan, Jamie L.
name: Song, Gina
name: Tarrant, Teresa K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Tumor cells are surrounded by a complex microenvironment. The purpose of our study was to evaluate the role of heterogeneity of the tumor microenvironment in the variability of nanoparticle (NP) delivery and efficacy.
Electronic Supporting Information from The in situ synthesis of PbS nanocrystals from lead(II) n-octylxanthate within a 1,3-diisopropenylbenzene–bisphenol A dimethacrylate sulfur copolymer.
Creators: name: P. D. McNaughter
name: J. C. Bear
name: A. G. Mayes
name: I. P. Parkin
name: P. O'Brien
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 30399 Macromolecular and Materials Chemistry not elsewhere classified
subject: FOS: Chemical sciences
subject: 100799 Nanotechnology not elsewhere classified
subject: FOS: Nanotechnology

description: Further results from the sulfur polymer synthesis and the sulfur polymer-nanocrystal films from NMR, DSC, photography, powder XRD, XPS, EDX, SAED and UV-vis.
Hedgehog-GLI Signaling Inhibition Suppresses Tumor Growth in Squamous Lung Cancer
Creators: name: Huang, Lingling
name: Hayes, D. Neil
name: Walter, Vonn
name: Onaitis, Mark
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Lung squamous cell carcinoma (LSCC) currently lacks effective targeted therapies. Previous studies reported overexpression of HEDGEHOG (HH)-GLI signaling components in LSCC. However, they addressed neither the tumor heterogeneity nor the requirement for HH-GLI signaling. Here, we investigated the role of HH-GLI signaling in LSCC, and studied the therapeutic potential of HH-GLI suppression.
title: Every second counts: Aortic dissection
Creators: name: Morais Aguiar Ferreira, Ana Isabel
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Arteries / Aorta
subject: Emergency
subject: Vascular
subject: CT
subject: CT-Angiography
subject: Complications
subject: Education
subject: Dissection
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: - Describe the pathophysiology and imaging presentation of the aortic dissection; - Optimizing the CT technique for its diagnosis and evaluation; - Present their prognosis, treatment modalities and main...
title: Imaging Assessment and Treatment of Intracranial Aneurysms
Creators: name: Andresciani, Flavio
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Interventional vascular
subject: Neuroradiology brain
subject: Vascular
subject: Catheter arteriography
subject: CT-Angiography
subject: MR-Angiography
subject: Embolisation
subject: Stents
subject: Treatment effects
subject: Aneurysms
subject: Haemorrhage

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: To provide a review of current techniques used to diagnose and follow-up patients with intracranial aneurysms as well as of endovascular therapeutic options available for treatment, highlighting the typical imaging features after endovascular...
Sparse Proteomics Analysis - A compressed sensing-based approach for feature selection and classification of high-dimensional proteomics mass spectrometry data
Creators: name: Conrad, Tim
name: Genzel, Martin
name: Cvetkovic, Nada
name: Wulkow, Niklas
name: Leichtle, Alexander
name: Vybiral, Jan
name: Kutyniok, Gitta
name: Schütte, Christof
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistics Theory (math.ST)
subject: Machine Learning (stat.ML)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: Background: High-throughput proteomics techniques, such as mass spectrometry (MS)-based approaches, produce very high-dimensional data-sets. In a clinical setting one is often interested in how mass spectra differ between patients of different classes, for example spectra from healthy patients vs. spectra from patients having a particular disease. Machine learning algorithms are needed to (a) identify these discriminating features and (b) classify unknown spectra based on this feature set. Since the acquired data is usually noisy, the algorithms should be robust against noise and outliers, while the identified feature set should be as small as possible. Results: We present a new algorithm, Sparse Proteomics Analysis (SPA), based on the theory of compressed sensing that allows us to identify a minimal discriminating set of features from mass spectrometry data-sets. We show (1) how our method performs on artificial and real-world data-sets, (2) that its performance is competitive with standard (and widely used) algorithms for analyzing proteomics data, and (3) that it is robust against random and systematic noise. We further demonstrate the applicability of our algorithm to two previously published clinical data-sets.
Three-dimensional simulations of near-surface convection in main-sequence stars. III. The structure of small-scale magnetic flux concentrations
Creators: name: Beeck, Benjamin
name: Schüssler, Manfred
name: Cameron, Robert H.
name: Reiners, Ansgar
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The convective envelopes of cool main-sequence stars harbour magnetic fields with a complex global and local structure. These fields affect the near-surface convection and the outer stellar atmospheres in many ways and are responsible for the observable magnetic activity of stars. Our aim is to understand the local structure in unipolar regions with moderate average magnetic flux density. These correspond to plage regions covering a substantial fraction of the surface of the Sun (and likely also the surface of other Sun-like stars) during periods of high magnetic activity. We analyse the results of 18 local-box magnetohydrodynamics simulations covering the upper layers of the convection zones and the photospheres of cool main-sequence stars of spectral types F to early M. The average vertical field in these simulations ranges from 20 to 500G. We find a substantial variation of the properties of the surface magnetoconvection between main-sequence stars of different spectral types. As a consequence of a reduced efficiency of the convective collapse of flux tubes, M dwarfs lack bright magnetic structures in unipolar regions of moderate field strength. The spatial correlation between velocity and the magnetic field as well as the lifetime of magnetic structures and their sizes relative to the granules vary significantly along the model sequence of stellar types.
description: 15 pages, 12 figures, accepted for publication in A&A
Electronic Supporting Information from The in situ synthesis of PbS nanocrystals from lead(II) n-octylxanthate within a 1,3-diisopropenylbenzene–bisphenol A dimethacrylate sulfur copolymer
Creators: name: P. D. McNaughter
name: J. C. Bear
name: A. G. Mayes
name: I. P. Parkin
name: P. O'Brien
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 30399 Macromolecular and Materials Chemistry not elsewhere classified
subject: FOS: Chemical sciences
subject: 100799 Nanotechnology not elsewhere classified
subject: FOS: Nanotechnology

description: Further results from the sulfur polymer synthesis and the sulfur polymer-nanocrystal films from NMR, DSC, photography, powder XRD, XPS, EDX, SAED and UV-vis.
title: Choroid plexus tumor: imaging contribution for grading
Creators: name: Mekouar, Younes
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: CNS
subject: Oncology
subject: Paediatric
subject: CT
subject: MR
subject: Diagnostic procedure
subject: Neoplasia

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: - To correlate the grade of the tumor with the imaging appearance by taking into account the different tumor characteristics : size, morphology, density on CT, signal on MRI, degree of enhancement, apparent diffusion coefficient, presence of...
Long distance coupling of resonant exchange qubits
Creators: name: Russ, Maximilian
name: Burkard, Guido
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the effectiveness of a microwave cavity as a mediator of interactions between two resonant exchange (RX) qubits in semiconductor quantum dots (QDs) over long distances, limited only by the extension of the cavity. Our interaction model includes the orthonormalized Wannier orbitals constructed from Fock-Darwin states under the assumption of a harmonic QD confinement potential. We calculate the qubit-cavity coupling strength in a Jaynes Cummings Hamiltonian, and find that dipole transitions between two states with an asymmetric charge configuration constitute the relevant RX quoit-cavity coupling mechanism. The effective coupling between two RX qubits in a shared cavity yields a universal two-qubit iSWAP-gate with gate times on the order of nanoseconds over distances on the order of up to a millimeter.
description: revised v2: 13 pages (including 5 appendices), 9 figures
title: Doppler resistive index to differentiate benign and malignant breast lesions and correlation with biopsy findings
Creators: name: H S, KARTHIK
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Breast
subject: Thorax
subject: Ultrasound physics
subject: Ultrasound
subject: Ultrasound-Colour Doppler
subject: Ultrasound-Spectral Doppler
subject: Biopsy
subject: Cancer
subject: Pathology
subject: Tissue characterisation

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Breast cancer is the most frequently diagnosed cancer. Breast masses can be benign or malignant and they come in a variety of shapes and sizes. Ultrasonography and doppler sonography is used to detect and differentiate between malignant & benign...
Molecular Pathways: Adaptive Kinome Reprogramming in Response to Targeted Inhibition of the BRAF-MEK-ERK Pathway in Cancer
Creators: name: Stuhlmiller, Timothy J.
name: Angus, Steven P.
name: Johnson, Gary L.
name: Zawistowski, Jon S.
name: Graves, Lee M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The central role of the BRAF-MEK-ERK pathway in controlling cell fate has made this pathway a primary target for deregulated activation in cancer. BRaf is activated by Ras proteins allowing Ras oncogenes to constitutively activate the pathway. Activating BRaf mutations are also frequent in several cancers, being the most common oncogenic mutation in thyroid carcinoma and melanoma. There are currently two inhibitors, vemurafenib and dabrafenib, approved for treatment of malignant melanoma having activating BRaf mutations. Concurrent administration of BRAF inhibitor and MEK inhibitor (trametinib) is significantly more active in patients with BRAF mutant melanoma than either single agent alone, but progression to resistance ultimately occurs by different mechanisms that increase the activation of ERK. Such adaptive changes in tumor cell signaling networks allows bypass of targeted oncoprotein inhibition. This is true with targeted inhibitors for BRaf and MEK as well as specific inhibitors for AKT, mTOR and many receptor tyrosine kinases such as EGFR and HER2. It is this adaptive response to targeted kinase inhibitors that contributes to the failure of single agent kinase inhibitors to have durable responses. This failure is seen in virtually all cancers treated with single agent kinase inhibitors, most of which are not as dependent on a single signaling pathway such as BRaf-MEK-ERK in melanoma. Thus, understanding the breadth of adaptive reprogramming responses to specific targeted kinase inhibition will be critical to develop appropriate combination therapies for durable clinical responses.
(401257) Janet Joiner
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
MPEC 2024-R216 : 2024 RS9
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 RS9

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Data from A dinosaur missing-link? Chilesaurus and the early evolution of ornithischian dinosaurs.
Creators: name: Baron, Matthew G.
name: Barrett, Paul M.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences
subject: 60301 Animal Systematics and Taxonomy
subject: 60310 Plant Systematics and Taxonomy

description: Characters scores for each taxon, the raw output of our analyses and further description of our methods and our results
Plaquette-triplon analysis of magnetic disorder and order in a trimerized spin-1 Kagomé antiferromagnet
Creators: name: Ghosh, Pratyay
name: Verma, Akhilesh Kumar
name: Kumar, Brijesh
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: A spin-1 Heisenberg model on trimerized Kagomé lattice is studied by doing a low-energy bosonic theory in terms of plaquette-triplons defined on its triangular unit-cells. The model has an intra-triangle antiferromagnetic exchange interaction, $J$ (set to 1), and two inter-triangle couplings, $J^\prime>0$ (nearest-neighbor) and $J^{\prime\prime}$ (next-nearest-neighbor; of both signs). The triplon analysis of this model studies the stability of the trimerized singlet (TS) ground state in the $J^\prime$-$J^{\prime\prime}$ plane. It gives a quantum phase diagram that has two gapless antiferromagnetically (AF) ordered phases separated by the spin-gapped TS phase. The TS ground state is found to be stable on $J^{\prime\prime}=0$ line (the nearest-neighbor case), and on both sides of it for $J^{\prime\prime}\neq 0$, in an extended region bounded by the critical lines of transition to the gapless AF phases. The gapless phase in the negative $J^{\prime\prime}$ region has a $\sqrt{3}\times\sqrt{3}$ coplanar $120^\circ$-AF order, with all the moments of equal length and relative angles of $120^\circ$. The other AF phase, in the positive $J^{\prime\prime}$ region, is found to exhibit a different coplanar order with ordering wave vector ${\bf q}=(0,0)$. Here, two magnetic moments in a triangle are of same magnitude, but shorter than the third. While the angle between the two short moments is $120^\circ-2δ$, it is $120^\circ+δ$ between a short and the long one. Only when $J^{\prime\prime}=J^\prime$, their magnitudes become equal and the relative-angles $120^\circ$. This ${\bf q}=(0,0)$ phase has the translational symmetry of the Kagomé lattice with isosceles triangular unit-cells. The ratio of the intensities of certain Bragg peaks, $I_{(1,0)}/I_{(0,1)} = 4\sin^2{(\fracπ{6}+δ)}$, presents an experimental measure of the deviation, $δ$, from the $120^\circ$ order.
description: 15 pages, 12 figures
(401253) Donald Stewart
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Disentangling the Quantum World
Creators: name: Price, Huw
name: Wharton, Ken
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: History and Philosophy of Physics (physics.hist-ph)
subject: Popular Physics (physics.pop-ph)
subject: FOS: Physical sciences

description: Correlations related to related to quantum entanglement have convinced many physicists that there must be some at-a-distance connection between separated events, at the quantum level. In the late 1940s, however, O. Costa de Beauregard proposed that such correlations can be explained without action at a distance, so long as the influence takes a zigzag path, via the intersecting past lightcones of the events in question. Costa de Beauregard's proposal is related to what has come to be called the retrocausal loophole in Bell's Theorem, but -- like that loophole -- it receives little attention, and remains poorly understood. Here we propose a new way to explain and motivate the idea. We exploit some simple symmetries to show how Costa de Beauregard's zigzag needs to work, to explain the correlations at the core of Bell's Theorem. As a bonus, the explanation shows how entanglement might be a much simpler matter than the orthodox view assumes -- not a puzzling feature of quantum reality itself, but an entirely unpuzzling feature of our knowledge of reality, once zigzags are in play.
description: 17 pages, 3 figures; significant revisions in response to referees' comments
Star formation rates and the kinematics of gas in the spiral arms of NGC 628
Creators: name: Gusev, Alexander S.
name: Sakhibov, Firouz
name: Efremov, Yury N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Relations between star formation rates along the spiral arms and the velocities of gas inflow into the arms in grand-design galaxy NGC 628 were studied. We found that the radial distribution of average star formation rate in individual star formation regions in regular spiral arms correlates with the velocity of gas inflow into the spiral arms. Both distributions have maxima at a galactocentric distance of 4.5-5 kpc. There are no correlations between the radial distributions of average star formation rate in star formation regions in spiral arms and outside spiral arms in the main disc. We also did not find a correlation between the radial distribution of average star formation rate in star formation regions in spiral arms and HI column density.
description: 8 pages, 6 figures, 1 table. Accepted for publication in Astronomische Nachrichten
title: Evaluation of the extent of locally advanced gastric cancer regression after preoperative chemotherapy by using computed tomography
Creators: name: Amelina, Inna
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: Oncology
subject: Stomach (incl. Oesophagus)
subject: CT
subject: Computer Applications-Detection, diagnosis
subject: Radiation therapy / Oncology
subject: Cancer
subject: Metastases

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: A multimodal approach to the treatment of locally advanced gastric cancer (GC) with the addition of systemic or local treatment methods, such as chemotherapy and radiation therapy, reduces the risk of cancer recurrence, thus improving survival of...
Molecular Pathways: Gene-Environment Interactions Regulating Dietary Fiber Induction of Proliferation and Apoptosis via Butyrate for Cancer Prevention
Creators: name: Bultman, Scott J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Gene-environment interactions are so numerous and biologically complicated that it can be challenging to understand their role in cancer. However, dietary fiber and colorectal cancer prevention may represent a tractable model system. Fiber is fermented by colonic bacteria into short-chain fatty acids such as butyrate. One molecular pathway that has emerged involves butyrate having differential effects depending on its concentration and the metabolic state of the cell. Low-moderate concentrations, which are present near the base of colonic crypts, are readily metabolized in the mitochondria to stimulate cell proliferation via energetics. Higher concentrations, which are present near the lumen, exceed the metabolic capacity of the colonocyte. Unmetabolized butyrate enters the nucleus and functions as a histone deacetylase (HDAC) inhibitor that epigenetically regulates gene expression to inhibit cell proliferation and induce apoptosis as the colonocytes exfoliate into the lumen. Butyrate may therefore play a role in normal homeostasis by promoting turnover of the colonic epithelium. Because cancerous colonocytes undergo the Warburg effect, their preferred energy source is glucose instead of butyrate. Consequently, even moderate concentrations of butyrate accumulate in cancerous colonocytes and function as HDAC inhibitors to inhibit cell proliferation and induce apoptosis. These findings implicate a bacterial metabolite with metaboloepigenetic properties in tumor suppression.
Data from A dinosaur missing-link? Chilesaurus and the early evolution of ornithischian dinosaurs
Creators: name: Baron, Matthew G.
name: Barrett, Paul M.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences
subject: 60301 Animal Systematics and Taxonomy
subject: 60310 Plant Systematics and Taxonomy

description: Characters scores for each taxon, the raw output of our analyses and further description of our methods and our results
Impact of the slit geometry on the performance of wire-grid polarisers
Creators: name: Mélen, Gwenaelle
name: Rosenfeld, Wenjamin
name: Weinfurter, Harald
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Wire-grid polarisers are versatile and scalable components which can be engineered to achieve small sizes and extremely high extinction ratios. Yet the measured performances are always significantly below the predicted values obtained from numerical simulations. Here we report on a detailed comparison between theoretical and experimental performances. We show that the discrepancy can be explained by the true shape of the plasmonic structures. Taking into account the fabrication details, a new optimisation model enables us to achieve excellent agreement with the observed response and to re-optimise the grating parameters to ensure experimental extinction ratios well above 1,000 at 850 nm.
description: 8 pages, 6 figures
title: Primary lymphoma of the breast: a rare entity
Creators: name: González Estévez, Mateo
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Breast
subject: Oncology
subject: Mammography
subject: MR
subject: Ultrasound
subject: Diagnostic procedure
subject: Cancer
subject: Lymphoma
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To describe the imaging findings and radio - pathological correlation of primary breast lymphomas diagnosed in our centre, and to compare them to the literature. To discuss the role of the different imaging techniques in the diagnosis of this...
Supplementary material from Socially cued seminal fluid gene expression mediates responses in ejaculate quality to sperm competition risk.
Creators: name: Simmons, Leigh W.
name: Lovegrove, Maxine
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Tables S1, S2 & S3
(401255) Frederick Doyle
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Methodological quality of ESC/AHA clinical practice guidelines of heart failure across the last two decades: a systematic critical appraisal using the AGREE II Tool.
Creators: name: Raúl, Quirós-López
name: Francisco, Estupiñán-Romero
name: Eduardo, Millán-Ortuondo
name: Enrique, Bernal-Delgado
name: Nicolás, Jiménez-García
Publisher: name: Zenodo
Year: 2024

description: The article systematically appraises the methodological quality of Clinical Practice Guidelines (CPGs) for heart failure (HF) published by the European Society of Cardiology (ESC) and the American Heart Association (AHA) over the past two decades, using the AGREE II tool. The research, conducted by the CONCEPT-HF group, evaluates the evolution of these guidelines' quality to determine improvements in areas like rigor, stakeholder involvement, and clarity.
Negative Magnetoresistance in Amorphous Indium Oxide Wires
Creators: name: Mitra, Sreemanta
name: Tewari, Girish C
name: Mahalu, Diana
name: Shahar, Dan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study magneto-transport properties of several amorphous Indium oxide nanowires of different widths. The wires show superconducting transition at zero magnetic field, but, there exist a finite resistance at the lowest temperature. The $R(T)$ broadening was explained by available phase slip models. At low field, and far below the superconducting critical temperature, the wires with diameter equal to or less than 100 nm, show negative magnetoresistance (nMR). The magnitude of nMR and the crossover field are found to be dependent on both temperature and the cross-sectional area. We find that this intriguing behavior originates from the interplay between two field dependent contributions.
description: 11 pages, 7 figures
Supplementary material from Socially cued seminal fluid gene expression mediates responses in ejaculate quality to sperm competition risk
Creators: name: Simmons, Leigh W.
name: Lovegrove, Maxine
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Tables S1, S2 & S3
Supplementary Material for “Connecting the dots across time: Reconstruction of single cell signaling trajectories using time-stamped data”.
Creators: name: Sayak Mukherjee
name: Stewart, David
name: Stewart, William
name: Lanier, Lewis L.
name: Jayajit Das
Publisher: name: The Royal Society
Year: 2017
Subjects: Biophysics
Computational Biology

description: Contains supplementary figures S1-S13, tables S1-S2, pseudocodes, and, derivations.
Propagation of Ultra High Energy Cosmic Rays and the Production of Cosmogenic Neutrinos
Creators: name: Aloisio, R.
name: Boncioli, D.
name: di Matteo, A.
name: Grillo, A. F.
name: Petrera, S.
name: Salamida, F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present an updated version of the {\it SimProp} Monte Carlo code to study the propagation of ultra high energy cosmic rays in astrophysical backgrounds computing the cosmogenic neutrino fluxes expected on earth. The study of secondary neutrinos provides a powerful tool to constrain the source models of these extremely energetic particles. We will show how the newly detected IceCube neutrino events at PeV energies together with the the latest experimental results of the Pierre Auger Observatory and Telescope Array experiment are almost at the level of excluding several hypothesis on the astrophysical sources of ultra high energy cosmic rays. Results presented here can be also used to evaluate the discovery capabilities of future high energy cosmic rays and neutrino detectors.
description: 4 pages, 4 pdf figures, talk given at the Neutrino Oscillation Workshop (NOW 2014), Otranto, Italy, September 7-14 2014
(401251) Henrietta Jack
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Tunable inertia of chiral magnetic domain walls
Creators: name: Torrejon, Jacob
name: Martinez, Eduardo
name: Hayashi, Masamitsu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The time it takes to accelerate an object from zero to a given velocity depends on the applied force and the environment. If the force ceases, it takes exactly the same time to completely decelerate. A magnetic domain wall (DW) is a topological object that has been observed to follow this behavior. Here we show that acceleration and deceleration times of chiral Neel walls driven by current are different in a system with low damping and moderate Dzyaloshinskii-Moriya (DM) exchange constant. The time needed to accelerate a DW with current via the spin Hall torque is much faster than the time it needs to decelerate once the current is turned off. The deceleration time is defined by the DM exchange constant whereas the acceleration time depends on the spin Hall torque, enabling tunable inertia of chiral DWs. Such unique feature of chiral DWs can be utilized to move and position DWs with lower current, key to the development of storage class memory devices.
title: Takayasu Disease : Imaging features
Creators: name: NEJMEDDINE, Amine
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Arteries / Aorta
subject: Vascular
subject: CT-Angiography
subject: MR-Angiography
subject: Diagnostic procedure
subject: Inflammation

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: - Stress the importance of imaging for establishing the diagnosis of Takayasu's arteritis in all its phases. - Illustrate the specifics of this pathology compared to others, such as Horton's...
Strongly coupled quantum heat machines
Creators: name: Gelbwaser-Klimovsky, David
name: Aspuru-Guzik, Alán
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum heat machines (QHMs) models generally assume a weak coupling to the baths. This supposition is grounded in the separability principle between systems and allows the derivation of the evolution equation for this case. In the weak coupling regime, the machine's output is limited by the coupling strength, restricting their application. Seeking to overcome this limitation, we here analyze QHMs in the virtually unexplored strong coupling regime, where separability, as well as other standard thermodynamic assumptions, may no longer hold. We show that strongly coupled QHMs may be as efficient as their weakly coupled counterparts. In addition, we find a novel turnover behavior where their output saturates and disappears in the limit of ultra-strong coupling.
Molecular Pathways: Targeting RAC-p21-Activated Serine-Threonine Kinase Signaling in RAS-Driven Cancers
Creators: name: Der, Channing J.
name: Chernoff, Jonathan
name: Baker, Nicole M.
name: Chow, Hoi Yee
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Cancers driven by oncogenic Ras proteins encompass some of the most deadly human cancer types, and there is a pressing need to develop therapies for these diseases. While recent studies suggest that mutant Ras proteins may yet be druggable, the most promising and advanced efforts involve inhibitors of Ras effector signaling. Most efforts to target Ras signaling have been aimed at the ERK mitogen-activated protein kinase and the phosphatidylinositol 3-kinase signaling networks. However, to date, no inhibitors of these Ras effector pathways have been effective against RAS mutant cancers. This ineffectiveness is due, in part, to the involvement of additional effectors in Ras-dependent cancer growth, such as the Rac small GTPase and the p21-activated serine-threonine kinases (PAK). PAK proteins are involved in many survival, cell motility, and proliferative pathways in the cell and may present a viable new target in Ras-driven cancers. In this review, we address the role and therapeutic potential of Rac and Group I PAK proteins in driving mutant Ras cancers.
title: MRI Radiomics in prostate cancer detection: a reliability study
Creators: name: Caliendo, Valentina
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Artificial Intelligence
subject: Genital / Reproductive system male
subject: Oncology
subject: MR
subject: Biopsy
subject: Imaging sequences
subject: Segmentation
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Radiomics can provide quantitative features from medical imaging that can be correlated to clinical endpoints. The robustness of radiomics features is influenced by acquisition and reconstruction protocols and by segmentation of the region of...
MPEC 2024-R217 : 2024 RT9
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 RT9

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Guido Wegelin an Louis Rollier (1859-1931), ergänzt um eine Nachschrift von Heinrich Wegelin (1853-1940)
Creators: name: Wegelin, Guido
Publisher: name: [s.n.]
Year: 1898

description: Brief ohne Ortsangabe.
Ergänzt um eine Nachschrift von Heinrich Wegelin, verfasst am 13.4.1898 in Frauenfeld
Three-dimensional simulations of near-surface convection in main-sequence stars. IV. Effect of small-scale magnetic flux concentrations on centre-to-limb variation and spectral lines
Creators: name: Beeck, Benjamin
name: Schüssler, Manfred
name: Cameron, Robert H.
name: Reiners, Ansgar
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Magnetic fields affect the local structure of the photosphere of stars. They can considerably influence the radiative properties near the optical surface, flow velocities, and the temperature and pressure profiles. We aim at understanding qualitatively the influence of small magnetic flux concentrations in unipolar plage regions on the centre-to-limb variation of the intensity and its contrast and on the shape of spectral line profiles in cool main-sequence stars. We analyse the bolometric and continuum intensity and its angular dependence of 24 radiative magnetohydrodynamic simulations of the near-surface layers of main-sequence stars with six different sets of stellar parameters (spectral types F to early M) and four different average magnetic field strengths (including the non-magnetic case). We also calculated disc-integrated profiles of three spectral lines. The small magnetic flux concentrations formed in the magnetic runs of simulations have a considerable impact on the intensity and its centre-to-limb variation. Spectral lines are not only broadened owing to the Zeeman effect, but are also strongly affected by the modified thermodynamical structure and flow patterns. This indirect magnetic impact on the line profiles is often bigger than that of the Zeeman effect. The effects of the magnetic field on the radiation leaving the star can be considerable and is not restricted to spectral line broadening and polarisation by the Zeeman effect. The inhomogeneous structure of the magnetic field on small length scales and its impact on (and spatial correlation with) the local thermodynamical structure and the flow field near the surface influence the measurement of the global field properties and stellar parameters. These effects need to be taken into account in the interpretation of observations.
description: 16 pages, 13+3 figures, 1 appendix, accepted for publication in A&A
Supplementary Material for “Connecting the dots across time: Reconstruction of single cell signaling trajectories using time-stamped data”
Creators: name: Sayak Mukherjee
name: Stewart, David
name: Stewart, William
name: Lanier, Lewis L.
name: Jayajit Das
Publisher: name: The Royal Society
Year: 2017
Subjects: Biophysics
Computational Biology

description: Contains supplementary figures S1-S13, tables S1-S2, pseudocodes, and, derivations.
Supporting Information for "The Role of Climatic and Geological Events in Generating Diversity in Ethiopian Grass Frogs (Genus Ptychadena) from The role of climatic and geological events in generating diversity in Ethiopian grass frogs (genus Ptychadena).
Creators: name: Smith, Megan L.
name: Noonan, Brice P.
name: Colston, Timothy J.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60301 Animal Systematics and Taxonomy
subject: 60310 Plant Systematics and Taxonomy

description: This file contains the supporting tables and figures, as well as PCR Conditions and on the gene tree analyses.
(401252) Katherine Barclay Jack [m Doyle]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supporting Information for "The Role of Climatic and Geological Events in Generating Diversity in Ethiopian Grass Frogs (Genus Ptychadena) from The role of climatic and geological events in generating diversity in Ethiopian grass frogs (genus Ptychadena)
Creators: name: Smith, Megan L.
name: Noonan, Brice P.
name: Colston, Timothy J.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60301 Animal Systematics and Taxonomy
subject: 60310 Plant Systematics and Taxonomy

description: This file contains the supporting tables and figures, as well as PCR Conditions and on the gene tree analyses.