cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Dereplication of Siparuna brasiliensis extract with in vivo anti-inflammatory activity
Creators: name: Castro, Leandro A.
name: Lima, Nerilson M.
name: Guarneire, Gracimério J.
name: Carli, Gabriela P.
name: Castro, Allyne Aparecida S.
name: de Jesus A. S. Andrade, Teresinha
name: Castro, Sandra B. R.
name: Vaz, Boniek Gontijo
name: Alves, Caio Cesar S.
name: Carli, Alessandra P.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Siparuna brasiliensis is a medicinal plant widely used by indigenous communities of the Amazon rainforest to treat inflammatory diseases and related pathologies. Considering its ethnopharmacological application, it constitutes an important source of biologically active molecules in the development of anti-inflammatory drugs. This study describes a dereplication methodology of the bioactive extract from S. brasiliensis leaves and the evaluation of the anti-inflammatory potential in an in vivo inflammatory model with mice of the BALB/c lineage and in vitro using cell lines, as well as determining the production of an inflammatory mediator. From their charge-to-mass ratios (m/z) and elemental composition obtained through Ultrahigh-resolution mass spectrometry analysis by ESI(-)-Orbitrap MS and chromatographic profile by RP-HPLC-PDA, it was possible to annotate polyphenols with anti-inflammatory properties classified as flavonoids and organic acids. The administration of the extract significantly inhibited carrageenan-induced paw edema and showed effects similar to those of drug dexamethasone without affecting cell viability.
Evaluation of Pasta Production Potential of Cassava and Sweet Potato Flour as A Partial Substitute of Durum Wheat Flour
Creators: name: Gosa Mamo
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Cassava; Cyanide; Flour blends; Pasta; Sweet potato

description: Pasta is unleavened extruded product which is made from dough of durum wheat
 flour and water; and it is also produced by mixing of composite flour. Cassava and
 sweet potato were processed into flours, and used to partially substitute durum wheat
 flour at different ratios (100:0:0, 90:5:5, 80:10:10, 70:15:15, 60:20:20 and 50:25:25),
 to prepare pasta. Durum wheat flour and its pasta product were used as a control.
 Comparisons between sample treatments were done using one way analysis of
 variance (ANOVA). The result showed that composite flour ranges for wet gluten
 10.65 ± 0.5% to 30.98 ± 0.03%. It was observed that, composite pasta showed
 significantly higher carbohydrate (65.33 to 73.87%) and energy value (336.0 to
 340.85Kcal/100g) but crude protein (8.85 to 15.52%) was found to be lower than
 control pasta. The results of sensory characteristics confirmed that substitution of
 wheat flour up to 20% with each cassava and sweet potato flours for pasta was
 slightly acceptable. Quality of desired pasta relies on different parameters or
 characteristics, such as gluten, water and oil absorption, dough properties, cooking
 quality and proximate composition.
Figure S1 from Social structure of the harem-forming promiscuous fruit bat, Cynopterus sphinx, is the harem truly important?
Creators: name: Kritika M. Garg
name: Balaji Chattopadhyay
name: Ramakrishnan, Uma
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 60801 Animal Behaviour

description: Frequency distribution of the observed association index.
Evaluation of Partial Replacement of Sawdust Ash As Filler Materials in Hot Mix Asphalt Mixture
Creators: name: Tsegaye Berhanu
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: concrete, mineral filler, sawdust ash, limestone, waste materials, ingredients

description: n Ethiopia the asphalt concrete road construction demand is expanding from time to
 time, but the supply of the ingredient materials is in great problem both in cost and
 amount. That means there is no an alternative locally available mineral filler and fair in
 cost comparably. The purpose of this investigation is to evaluate the suitability of
 sawdust ash as filler materials in the production of hot mix asphalt mixture by using
 Marshall Mix design method. After the materials are collected from IFH construction
 company stock, the quality tests are conducted both for aggregates and bitumen. The
 design procedure, uses two mineral fillers; limestone the reference filler and the sawdust
 ash being investigated. In laboratory test 0 - 20% of the sawdust ash is replaced by
 limestone in a range of 5% gap in order to evaluate the suitability of sawdust ash as a
 filler material. The carbon content of sawdust ash is 67.72%, as a result the rate of
 conversion of sawdust into an ash becomes around 3%. The partial replacement of
 sawdust ash by limestone almost fulfills the desired performance properties of bituminous
 mixtures. At 15% sawdust ash content, all the desired performance properties are
 achieved and the optimum bitumen content is 5.15% which is more economical and
 suitable. The Marshall stability at this point is 12.64KN much larger than the specified
 range. Then, 15% sawdust ash content is considered as an optimum filler content which
 keeps the balance among all the desired performance properties of the bituminous
 asphalt mixtures. The desired performance parameter of Marshall Mix design asserted
 that the partial replacement of sawdust ash by limestone fulfills the suitability. And the
 addition of sulfuric acid into sawdust ash exhibited identical characteristics to that of
 limestone filler. This technique is another mechanism to identify suitable fillers from the
 other. In its way, this study definitely answers the problems regarding scarcity of locally
 available filler material, environmental impacts and generates of income from
 byproducts for the societies. Lastly, further investigations are needed to standardize the
 use of sawdust ash alone as filler material in any bituminous mixture.
Supporting tables from Social structure of the harem-forming promiscuous fruit bat, Cynopterus sphinx, is the harem truly important?
Creators: name: Kritika M. Garg
name: Balaji Chattopadhyay
name: Ramakrishnan, Uma
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 60801 Animal Behaviour

description: File contains supplementary tables S1 to S4.
Characterization of stenocephol from Seriphidium stenocephalum as potent HepG2 cell growth and glycogen phosphorylase inhibitor
Creators: name: Shafiq, Nusrat
name: Arshad, Uzma
name: Brogi, Simone
name: Rashid, Maryam
name: Rafiq, Naila
name: Parveen, Shagufta
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Hematology

description: Plant-derived compounds represent an important source for developing innovative drugs. One of the widely distributed plants, especially in Afghanistan and Pakistan, Seriphidium stenocephalum, was investigated in this study to identify bioactive compounds. The plant extract was subjected to silica gel column chromatography, four phenolic acid derivatives were isolated, while stenocephol was obtained by ethyl acetate fraction. Stenocephol was subjected to experimental screening for anti-diabetic and anti-cancer activities, measuring its inhibitory potency against glycogen phosphorylase, and its cytotoxicity against HepG2 cells. Further insights into the mechanism of action of stenocephol were obtained from a computational investigation. Stenocephol showed a dose-dependent manner of inhibition against glycogen phosphorylase and HepG2 cells in the low micromolar range. Notably, coupling in vitro and computational investigation, we identified the natural product stenocephol as a possible anti-diabetic and anti-cancer agent, representing a possible starting point for developing novel therapeutics, enriching the armamentarium against the mentioned diseases.
Estimating school effectiveness with student growth percentile and gain score models
Creators: name: Wright, Daniel B.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Measuring school effectiveness using student test scores is controversial and some methods used for this can be inaccurate in some situations. The validity of two statistical models – the Student Growth Percentile (SGP) model and a multilevel gain score model – are evaluated. The SGP model conditions on previous test scores thereby unblocking a backdoor path between true school/teacher effectiveness and student test scores. When the product of the coefficients that make up this unblocked backdoor path is positive, the SGP estimates can be inaccurate. The accuracy of the multilevel gain score model was not associated with the product of this backdoor path. The gain score model appears promising in these situations where the SGP and other covariate adjusted models perform poorly.
Additional file 1 of Establishing an enzyme cascade for one-pot production of α-olefins from low-cost triglycerides and oils without exogenous H2O2 addition
Creators: name: Jiang, Yuanyuan
name: Li, Zhong
name: Zheng, Shanmin
name: Xu, Huifang
name: Zhou, Yongjin J.
name: Gao, Zhengquan
name: Meng, Chunxiao
name: Li, Shengying
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Computational Biology

description: Additional file 1: Figure S1. SDS-PAGE analysis of the secretory lipase Lip2 from Yarrowia lipolytica (lane A) and protein marker (M). Figure S2. SDS-PAGE analysis of the purified N-His6-tagged OleTJE (lane A), N-His6-AldO (lane B), and protein marker (M). Figure S3. Comparison of α-olefin producing activities of freshly purified proteins and the lyophilized enzymes in the CRL-OleTJE-AldO tandem reaction system using 500 μM coconut oil as substrate. Error bars represent standard deviations derived from at least two independent experiments. Figure S4. (a) Total FFAs released from 1500 μM coconut oil by three different amounts of CRL; (b) the effect of CRL amount on the α-olefin production from 1500 μM coconut oil by the CRL/OleTJE/AldO system (3 μM OleTJE, 15 μM AldO, and 10% glycerol at 30 °C for 6 h). Error bars represent standard deviations derived from at least two independent experiments. Statistical analysis was performed using a Student’s t test (one-tailed; *P < 0.05, **P < 0.01, ns: P > 0.05, no significant; two-sample unequal variance). Table S1. Primers used in this study. Table S2. Released FFA profiles of different natural oils by lipase CRL. Table S3. Released FFA profiles of different natural oils by lipase AOL. Table S4. Distribution of α-olefins produced from natural oils by the tandem hydrolysis–oxidation-–decarboxylation reaction system of CRL/OleTJE/AldO. Table S5. Distribution of α-olefins produced from natural oils by the tandem hydrolysis–oxidation–decarboxylation reaction system of AOL/OleTJE/AldO.
title: Émotions et enseignement
title: Émotions et enseignement
titleType: AlternativeTitle
Creators: name: Bertoli, Sara
Publisher: name: Unknown
Year: 0
Subjects: subject: émotions des enseignants
subject: sentiment d’auto-efficacité
subject: engagement dans le métier
subject: secondaire I du Canton de Vaud
subject: secondaire II du Canton de Vaud
subject: enseignants débutants

description: Le métier d’enseignant demande un investissement et une implication importants qui suscitent des émotions différentes d’une personne à l’autre. En effet, comme tout individu, l’enseignant ressent des émotions qui affectent positivement ou négativement son enseignement en ayant des effets aussi sur les apprentissages des élèves. Ainsi, la classe est le lieu privilégié pour la naissance des émotions. Dans le présent travail nous avons voulu étudier les émotions éprouvées par les enseignants du secondaire I et II du Canton de Vaud ainsi que leur impact sur le sentiment d’auto-efficacité et l’engagement dans le métier. De plus, nous avons voulu mettre la focale sur les enseignants en formation, ceux-ci étant particulièrement touchés par des émotions parfois contradictoires qui peuvent miner leur projet de devenir enseignants. Ainsi, à travers une étude comparative, nous avons également voulu vérifier le rôle joué par l’ancienneté en vérifiant quelles différences existent entre les enseignants débutants, semi-expérimentés et expérimentés au sujet des émotions, du sentiment d’auto-efficacité et l’engagement dans le métier. En particulier, l’attention aux enseignants débutants dérive du cadre dans lequel cette recherche s’insère, à savoir le mémoire concluant la formation à la Haute école pédagogique du Canton de Vaud. En effet, la thématique des émotions auprès des enseignants novices semble être peu prise en compte dans les lieux de formation. Cependant, ce thème suscite toujours plus d’intérêt auprès tous les acteurs de l’école, d’autant plus que les études les plus récents mettent en évidence l’influence des émotions dans le contexte scolaire.
КОНСТИТУЦИОННЫЕ ГАРАНТИИ ПРАВА НА ТРУД В РЕСПУБЛИКЕ УЗБЕКИСТАН: МЕЖДУ ТЕОРИЕЙ И РЕАЛЬНОСТЬЮ
Creators: name: Франклин, Делано
Publisher: name: Zenodo
Year: 2025

description: В данной статье рассматриваются конституционные гарантии права на труд в Республике Узбекистан, их законодательное развитие и проблемы практического применения. Особое внимание уделено личному опыту нарушения трудовых прав, который иллюстрирует разрыв между нормами права и реальной жизнью. Статья подчёркивает необходимость повышения правовой культуры среди граждан и совершенствования механизмов защиты их трудовых прав.
Evaluation of The Impact of strategic Public-Private- Partnership on Sustainable Development : case Study of Addis Ababa-Adama Express way
Creators: name: Feven  Behailu Aferu
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020

description: Public private partnership is one of the strategic moves for countries sustainable development. It
 is an important tool to create a development which considers economic, social and
 environmental aspects with a futuristic sustainable development in mind. Most researchers in
 this topic are only focused on the economic aspects of PPP, but offer limited analysis of the
 social and environmental consequences offering an incomplete view of the overall impact of
 PPP. This research offers an evaluation of PPP, and determined their potential to create social
 and environmental value, in addition to their value of money. The research used a case study
 research design, taking the case of Addis Ababa – Adama expressway project. By using
 purposive sampling method respondents from stakeholder organizations were selected to collect
 data, from questionnaires and interviews. The data from respondents was analyzed by using
 “EASIER” evaluation model. By this evaluation it was found that the public private partnership
 on this project had a high impact on sustainable development, the PPP had a very high impact
 on economic dimension but the project’s provision of access was lower and had a medium
 impact. Based on the data it can be concluded that PPP have a potential to positively affect and
 reflect sustainable development and the dimensions of sustainable development shapes the
 direction of infrastructure projects toward public private partnership. This research can serve as
 a bench mark for evaluation and be used to create a national evaluation framework.
Cytotoxic activity of the crude polysaccharides/exopolysaccharides of Coprinus comatus and Coprinellus truncorum
Creators: name: Atlagić, Kristina
name: Živić, Miroslav
name: Jakovljević, Dragica
name: Filipović, Jelena Marković
name: Šibul, Filip
name: Pejin, Boris
name: Karaman, Maja
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Fungi are an important source of polysaccharides (PSH) and phenolic compounds (PC). Numerous studies have highlighted the beneficial effects of fungal consumption, but the impact of submerged cultivated mycelia (M) and filtrate (F) has not been fully investigated. We aimed to investigate the cytotoxic activity of isolated crude PSH and exopolysaccharides (ePSH) of submerged cultivated M and F of edible Coprinus comatus and Coprinellus truncorum species. Both PSH and ePSH exhibited significant cytotoxic activity towards HepG2 cancer cells of human origin (three-way ANOVA). The C. truncorum PSH/ePSH was more efficient inducing maximal reduction in cell viability (≈50% at 450 µg/mL) after 24 h while C. comatus PSH/ePSH needed 72 h to reach similar effect (≈60% at 450 µg/mL). Partial least square regression (PLSR) analysis indicated that specific phenolic composition of the PSH/ePSH could be responsible for the difference in their activity.
Reservoir modelling strategies for intra-reservoir faulting
Creators: name: Oldfield, Simon
name: Lynch, Tom
name: Hilton, Jamie
name: Lecomte, Isabelle
name: Paton, Douglas
name: Fisher, Quentin J
Publisher: name: figshare
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: 40312 Structural Geology
subject: 40309 Petroleum and Coal Geology
subject: Geophysics
subject: 40407 Seismology and Seismic Exploration

description: Conference presentation, presented at: Handling Fault Seals, Baffles, Barriers and Conduits.

Hosted by the Geological Society of London, 15-17 November 2017
Abstract:
Small-scale, intra-reservoir faulting challenges reservoir modelling due to the large ambiguity of potential effects on fluid flow. Acquiring dynamic data during appraisal supplements prior information, however simulation is required to understand the sensitivity of the system. Contemporary reservoir modelling requires early definition of a grid geometry, affecting estimated hydrocarbon volumes which may inspire reluctance to adjust reservoir geometry. Faulting may affect reservoir flow properties by locally affecting the reservoir permeability and connectivity; affecting transmissibility across the fault itself and any related damage zone; and, by increasing tortuosity through displacement and juxtaposition of rock types with differing flow properties. To consider these in flow simulation, we may represent faulting using various strategies, including: geometric expression of the fault, including juxtaposition and transmissibility of flow across the fault; vertical expression of the fault in an unchanged grid geometry with application of transmissibility multipliers; or, assuming fault effect is negligible and will be considered by calibration of the bulk permeability of the reservoir. We present a series of reservoir simulations, representing each of these strategies to retrospectively add consideration of small-scale faulting. Using these data, we discuss the implication of modelling strategy on the results. Considering the purpose of reservoir modelling to be to facilitate decision-making. We consider this work to provide a first-pass sensitivity analysis of production forecasting to simulation strategy. This provides the first stage of information to consider if further investigation is warranted, establishing broad sensitivities and allowing consideration of potential impact.
Bioactive compounds of the Opuntia monacantha fruit
Creators: name: da Silva, Vinicius M.
name: de Sousa, Matheus H. Oliveira
name: Silva, Roberto S. G.
name: Flach, Adriana
name: de Moura, Neusa Fernandes
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology
subject: Virology

description: Opuntia monacantha is a Cactaceae found in regions with few nutrients and water. This study aimed to identify bioactive compounds in the fruit of O. monacantha in the southern region of Brazil. In the fruit of O. monacantha, five phenolic compounds were identified: protocatechuic acid, ferulic acid, p-coumaric acid, catechin and quercetin. The ferulic acid and catechin were found in higher concentration in the fruit. The terpenes α-amyrin, β-amyrin, oleanolic acid and cycloartenol were also identified in the hexane fractions of the fruit. Unsaturated fatty acids were found in the fruit seed, with the highest concentration of linoleic acid (69.0%).
Additional file 1 of Health-related quality of life and associated factors among cervical cancer patients at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia
Creators: name: Araya, Liya Teklu
name: Fenta, Teferi Gedif
name: Sander, Beate
name: Gebremariam, Girma Tekle
name: Gebretekle, Gebremedhin Beedemariam
Publisher: name: figshare
Year: 2020
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Additional file 1: S1. EORTC QLQ-C30 (version 3) and EORTC QLQ-CX24.
Structural characterization of a pectic polysaccharide from laoshan green tea and its inhibitory effects on the production of NO, TNF-α and IL-6
Creators: name: Liu, Fan
name: Wang, Rongshen
name: Chen, Ying
name: Geng, Rui
name: Gao, Hong
name: Wang, Feng
name: Liu, Xiaoxiao
name: Li, Wanzhong
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: A novel pectic polysaccharide, named GTPS3-1, was isolated and purified from Laoshan green tea polysaccharide (GTPS) through DEAE Sepharose Fast Flow and Sephacryl S-300 columns, its structure was characterized and its anti-inflammatory activity was explored. GTPS3-1, with a molecular weight of 26.05 kDa, was mainly composed of galacturonic acid, galactose, rhamnose and arabinose in a molar ratio of 4.72:2.5:1.68:1 on the basis of monosaccharide composition. Structural analysis results revealed that GTPS3-1 was a highly branched pectin consisting of →3)-Galp-(1→, →2)-Rhap-(1→, →3,5)-Araf-(1→, →3)-Rhap-(1→, GalpA-(1→, →3,4)-Galp-(1→, →4)-GalpA-(1→, →5)-Araf-(1→, →2,4)-Rhap-(1→, Rhap-(1→ and Araf-(1→ according to FT-IR, methylation and NMR analyses. In addition, GTPS3-1 inhibited the production of NO, TNF-α and IL-6 in a dose-dependent manner, which resulted in the amelioration of inflammatory injury in LPS-induced RAW 264.7 cells. These results would provide a theoretical basis for practical application of the novel polysaccharide as an anti-inflammatory adjuvant.
СОВРЕМЕННОЕ СОСТОЯНИЕ ВОДНЫХ ОБЪЕКТОВ КАРЕЛИИ В РЕЗУЛЬТАТЕ ВОЗДЕЙСТВИЯ ПРИРОДНЫХ, КЛИМАТИЧЕСКИХ И АНТРОПОГЕННЫХ ФАКТОРОВ / ВОДНОЕ ХОЗЯЙСТВО РОССИИ: ПРОБЛЕМЫ, ТЕХНОЛОГИИ, УПРАВЛЕНИЕ
Creators: name: Лозовик П.А.
name: Галахина Н.Е.
name: Кравченко И.Ю.
Publisher: name: figshare
Year: 2018
Subjects: subject: 50206 Environmental Monitoring
subject: FOS: Earth and related environmental sciences

description: Показано изменение состояния некоторых водных объектов Республики Карелия в результате антропогенного воздействия, а также роль атмосферных осадков в формировании химического состава поверхностных вод. Дана оценка поступления биогенных элементов и органического вещества в Онежское и Ладожское озера от различных природных и антропогенных источников. Для Онежского озера установлена более высокая нагрузка от точечных источников по сравнению с рассеянными, чем для Ладожского. Представлено многолетнее изменение химического состава воды Выгозерского водохранилища, принимающего сточные воды Сегежского ЦБК, и системы р. Кенти, в которую поступают техногенные воды Костомукшского ГОКа. Установлено, что атмосферные осадки являются основным источником поступления биогенных элементов и тяжелых металлов, тогда как выпадение минеральных и органических веществ с осадками незначительно. Впервые дана оценка состояния водных объектов Карелии в результате воздействия природных, климатических и антропогенных факторов.
СОВРЕМЕННОЕ СОСТОЯНИЕ ВОДНЫХ ОБЪЕКТОВ КАРЕЛИИ В РЕЗУЛЬТАТЕ ВОЗДЕЙСТВИЯ ПРИРОДНЫХ, КЛИМАТИЧЕСКИХ И АНТРОПОГЕННЫХ ФАКТОРОВ
Creators: name: Лозовик П.А.
name: Галахина Н.Е.
name: Кравченко И.Ю.
Publisher: name: figshare
Year: 2018
Subjects: subject: 50206 Environmental Monitoring
subject: FOS: Earth and related environmental sciences

description: Показано изменение состояния некоторых водных объектов Республики Карелия в результате антропогенного воздействия, а также роль атмосферных осадков в формировании химического состава поверхностных вод. Дана оценка поступления биогенных элементов и органического вещества в Онежское и Ладожское озера от различных природных и антропогенных источников. Для Онежского озера установлена более высокая нагрузка от точечных источников по сравнению с рассеянными, чем для Ладожского. Представлено многолетнее изменение химического состава воды Выгозерского водохранилища, принимающего сточные воды Сегежского ЦБК, и системы р. Кенти, в которую поступают техногенные воды Костомукшского ГОКа. Установлено, что атмосферные осадки являются основным источником поступления биогенных элементов и тяжелых металлов, тогда как выпадение минеральных и органических веществ с осадками незначительно. Впервые дана оценка состояния водных объектов Карелии в результате воздействия природных, климатических и антропогенных факторов.
Additional file 2 of Health-related quality of life and associated factors among cervical cancer patients at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia
Creators: name: Araya, Liya Teklu
name: Fenta, Teferi Gedif
name: Sander, Beate
name: Gebremariam, Girma Tekle
name: Gebretekle, Gebremedhin Beedemariam
Publisher: name: figshare
Year: 2020
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Additional file 2: S2. Mean differences of EORTC QLQ-C30 functional scale with demographic and clinical characteristics of patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.
Engineering Clostridium acetobutylicum to utilize cellulose by heterologous expression of a family 5 cellulase
Creators: name: Sanitha, Mary
name: Fathima, Anwar Aliya
name: Tolonen, Andrew C.
name: Ramya, Mohandass
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: Developmental Biology
subject: Marine Biology
subject: Plant Biology

description: Innovative processes to transform plant biomass into renewable chemicals are needed to replace fossil fuels and limit climate change. Clostridium acetobutylicum is of industrial interest because it ferments sugars into acetone, butanol and ethanol (ABE). However, this organism is unable to depolymerize cellulose, limiting its use for the direct transformation of lignocellulose. In this study, the freely secreted family 5 cellulase cphy2058 from Clostridium phytofermentans was efficiently expressed in C. acetobutylicum to enhance cellulolysis. RT-qPCR confirmed the transcription of the cellulase gene, and galactomannan and carboxymethyl cellulose plate assays showed endoglucanase and mannanase activity of cphy2058. ABE titers by the recombinant, cellulase-expressing C. acetobutylicum reached 85.83 mM in cellobiose cultures, whereas ABE titers by wild-type were 44.52 mM. ABE titers by the cellulase-expressing strain were similarly elevated relative to wild-type in cellulose and galactomannan cultures. These results demonstrate a novel strategy to enhance complex substrate utilization by heterologous cellulase expression in C. acetobutylicum.
Chemical characterization of acid-pretreated renewable resources: effect of pretreatment time
Creators: name: Germec, Mustafa
name: Ozcan, Ali
name: Turhan, Irfan
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology

description: The production of value-added products from renewable resources by fermentation is very attractive. In this study, the effect of pretreatment time on the chemical composition of acid-pretreated tea processing waste (TPW), spent tea waste (STW), barley husk (BH), and rye bran (RB) was examined. After the pretreatment processes, reducing sugar concentration (RSC), phenolics (PHs), glucose (Glc), xylose (Xyl), arabinose (Ara), acetic acid (AA), D-glucuronic acid (D-GA), 5-hydroxymethyl furfural (HMF), 2-furaldehyde (2-F) and catalytic efficiency (E, g sugars/g inhibitors) were determined. Results indicated that maximum E values were 3.79, 4.57, 21.28, and 33.46 g/g when the pretreatment times were 50, 6, 30, and 1 min for TPW, STW, BH, and RB, respectively. At these E values, the levels of RSC, PHs, Glc, Xyl, Ara, AA, D-GA, and HMF were 22.85, 1.60, 2.76, 6.98, 4.26, 1.28, 0.62, and 0.81 g/L for TPW; 17.67, 1.12, 1.55, 4.80, 4.05, 0.91, 0.98, and 0.25 g/L for STW; 64.30, 1.25, 30.14, 16.05, 3.57, 0.85, 0.00, and 0.23 g/L for BH; and 66.62, 0.79, 35.21, 13.08, 4.44, 0.00, 0.00, and 0.80 g/L for RB, respectively. Consequently, the hydrolysates obtained after suitable pretreatment times can be evaluated as substrate after removal of the inhibitors formed when necessary.
MOESM1 of Diverse effects of nitric oxide reductase NorV on Aeromonas hydrophila virulence-associated traits under aerobic and anaerobic conditions
Creators: name: Liu, Jin
name: Dong, Yuhao
name: Wang, Nannan
name: Ma, Shuiyan
name: Lu, Chengping
name: Liu, Yongjie
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Virology

description: Additional file 1. Primers used in this study.
Characterization of stenocephol from Seriphidium stenocephalum as potent HepG2 cell growth and glycogen phosphorylase inhibitor
Creators: name: Shafiq, Nusrat
name: Arshad, Uzma
name: Brogi, Simone
name: Rashid, Maryam
name: Rafiq, Naila
name: Parveen, Shagufta
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Hematology

description: Plant-derived compounds represent an important source for developing innovative drugs. One of the widely distributed plants, especially in Afghanistan and Pakistan, Seriphidium stenocephalum, was investigated in this study to identify bioactive compounds. The plant extract was subjected to silica gel column chromatography, four phenolic acid derivatives were isolated, while stenocephol was obtained by ethyl acetate fraction. Stenocephol was subjected to experimental screening for anti-diabetic and anti-cancer activities, measuring its inhibitory potency against glycogen phosphorylase, and its cytotoxicity against HepG2 cells. Further insights into the mechanism of action of stenocephol were obtained from a computational investigation. Stenocephol showed a dose-dependent manner of inhibition against glycogen phosphorylase and HepG2 cells in the low micromolar range. Notably, coupling in vitro and computational investigation, we identified the natural product stenocephol as a possible anti-diabetic and anti-cancer agent, representing a possible starting point for developing novel therapeutics, enriching the armamentarium against the mentioned diseases.
Elicitor mediated enhancement of shoot biomass and lupeol production in Hemidesmus indicus (L.) R. Br. ex. Schult. and Tylophora indica (Burm. F.) Merrill using yeast extract and salicylic acid
Creators: name: Pathak, Ashutosh R.
name: Patel, Swati R.
name: Joshi, Aruna G.
name: Shrivastava, Neeta
name: Sindhav, Gaurang
name: Sharma, Sonal
name: Ansari, Hafsa
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Hemidesmus indicus (L.) R. Br. ex Schult. and Tylophora indica (Burm. F.) Merrill shoot cultures were treated with different concentrations of yeast extract (YE; 25–200 mg/L) and salicylic acid (SA; 50–200 µM), and their effect on lupeol production was assessed. The maximum dry weight (DW) biomass was recorded when H. indicus shoots were treated with SA (50 µM) and T. indica shoots with YE (200 mg/L). Highest lupeol yield (335.40 ± 0.04 µg/g DW) was obtained in H. indicus shoots after treatment with 50 µM of SA for 3 weeks. Whereas in T. indica, maximum lupeol content (584.26 ± 8.14 µg/g DW) was recorded by giving treatment with 25 μM of SA for 6 weeks.
Rubber seed (Hevea brasiliensis) oil biodiesel emission profiles and engine performance characteristics using a TD202 diesel test engine
Creators: name: Onoji, Samuel Erhigare
name: Iyuke, Sunny E.
name: Igbafe, Anselm I.
name: Daramola, Michael O.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: In this study, biodiesel produced from seeds obtained from a Nigerian bioengineered rubber tree (Hevea brasiliensis, NIG800 series) was investigated for engine performance analysis and emission study. All tests were conducted for diesel, biodiesel, and blends over the entire speed range (1500–3500 rpm, at increments of 500 rpm) under full load operating conditions. The results showed that the brake specific fuel consumption is higher for biodiesel and blends compared to diesel due to the lower heating value of the biodiesel, but B20 and diesel results were the same (0.20 kg/kWh) at 2750 rpm. Exhaust gas temperature is significantly higher for biodiesel because the higher oxygen content (10–12%) and higher cetane number assisted complete combustion. Engine power, brake thermal efficiency, and engine torque were higher with diesel fuel compared to biodiesel and blends because of the higher energy content of diesel fuel. There is a significant reduction in carbon monoxide, unburned total hydrocarbons, and smoke opacity with biodiesel, but nitric oxide and carbon dioxide increased slightly. The B20 blend at 2500 rpm shows the best performance, and biodiesel sourced from rubber seeds is environmentally friendly and can be used in modern diesel engines without technical modifications.
Structural characterization of a pectic polysaccharide from laoshan green tea and its inhibitory effects on the production of NO, TNF-α and IL-6
Creators: name: Liu, Fan
name: Wang, Rongshen
name: Chen, Ying
name: Geng, Rui
name: Gao, Hong
name: Wang, Feng
name: Liu, Xiaoxiao
name: Li, Wanzhong
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: A novel pectic polysaccharide, named GTPS3-1, was isolated and purified from Laoshan green tea polysaccharide (GTPS) through DEAE Sepharose Fast Flow and Sephacryl S-300 columns, its structure was characterized and its anti-inflammatory activity was explored. GTPS3-1, with a molecular weight of 26.05 kDa, was mainly composed of galacturonic acid, galactose, rhamnose and arabinose in a molar ratio of 4.72:2.5:1.68:1 on the basis of monosaccharide composition. Structural analysis results revealed that GTPS3-1 was a highly branched pectin consisting of →3)-Galp-(1→, →2)-Rhap-(1→, →3,5)-Araf-(1→, →3)-Rhap-(1→, GalpA-(1→, →3,4)-Galp-(1→, →4)-GalpA-(1→, →5)-Araf-(1→, →2,4)-Rhap-(1→, Rhap-(1→ and Araf-(1→ according to FT-IR, methylation and NMR analyses. In addition, GTPS3-1 inhibited the production of NO, TNF-α and IL-6 in a dose-dependent manner, which resulted in the amelioration of inflammatory injury in LPS-induced RAW 264.7 cells. These results would provide a theoretical basis for practical application of the novel polysaccharide as an anti-inflammatory adjuvant.
title: ADCO, Cartulaire de Cîteaux pour les domaines de Beaune (XVe siècle), Cart. 177 (11 H 289), 197 folios, f. 0223
Creators: name: de la Côte d'Or, Archives départementales
name: CG21/F.PETOT/2015
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire de Cîteaux pour les domaines de Beaune (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 177 (11 H 289), 197 folios, f. 0223, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions d’Izeure (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 177 (11 H 289), 197 folios, f. 0223, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Lipid metabolism regulatory activity and adverse effects of fungi-derived butyrolactone I
Creators: name: Gu, Tanwei
name: Chen, Weihao
name: She, Jianglian
name: Yang, Bin
name: Tang, Lan
name: Tao, Huaming
name: Huang, Jingxia
name: Zhou, Xuefeng
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Butyrolactone I (BTL-I), a butenolide compound isolated from land or marine-derived fungi, has been reported to show diverse activities. To further study the pharmaceutical potential of BTL-I, transcriptome and bioinformatics analysis of BTL-I treated HepG2 cells were taken. BTL-I was revealed with lipid metabolism regulatory activity and confirmed by increasing the mRNA expression of related genes, such as LXRα and its target gene UGT1A1. However, the obvious chemical carcinogenesis of BTL-I was also disclosed. BTL-I could significantly increase the mRNA and protein levels of oncogenes such as CYP1A1. Molecular docking of BTL-I and its analogs were performed to understand the active or toxic effects. Although BTL-I showed attractive activities, enough attention must be paid to its adverse effects in its further development.
Geo-tagged street level imagery collection set-up
Creators: name: D'Andrimont, Raphael
name: Lemoine, Guido
name: Velde, Marijn Van Der
Publisher: name: figshare
Year: 2018
Subjects: subject: 70199 Agriculture, Land and Farm Management not elsewhere classified
subject: FOS: Other agricultural sciences
subject: 90905 Photogrammetry and Remote Sensing
subject: FOS: Environmental engineering

description: Description of a mount to collect field data.
การประเมินระบบเฝ้าระวังโรคหัด 3 จังหวัดชายแดนภาคใต้ประเทศไทย พ.ศ. 2556
Creators: name: นลินี ช่วยดำรง
Publisher: name: สำนักจัดการความรู้ กรมควบคุมโรค กระทรวงสาธารณสุข
Year: 2557
Subjects: การประเมินระบบเฝ้าระวัง
โรคหัด

description: วารสารควบคุมโรค, 40, 4, 302-309
การศึกษาประสิทธิผลของมาตรการในการป้องกันควบคุมโรคมือ เท้า ปากในศูนย์เด็กเล็ก
Creators: name: สมนึก เลิศสุโภชวณิชย์
Publisher: name: สำนักจัดการความรู้ กรมควบคุมโรค กระทรวงสาธารณสุข
Year: 2557
Subjects: มาตรการในการป้องกันควบคุมโรคมือ เท้า ปาก ในศูนย์เด็กเล็ก
ศูนย์เด็กเล็ก
อัตราป่วยของโรคมือ เท้า ปาก

description: วารสารควบคุมโรค, 40, 4, 310-320
Triterpene constituents from the fruits of Cyclocarya paliurus and their anti-HIV-1IIIB activity
Creators: name: Tu, Wen-Chao
name: Luo, Rong-Hua
name: Yuan, En
name: Sakah, Kaunda-Joseph
name: Yang, Quan-Yu
name: Xiao, Wei-Lie
name: Zheng, Yong-Tang
name: Liu, Mei-Feng
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Information Systems not elsewhere classified
subject: Virology

description: Four new norceanothane-type triterpenes, cyclopalin A-D (1-4), and sixteen known compounds (5-20) were obtained from the fruits of Cyclocarya paliurus. Their structures were determined by spectroscopic data, experimental electronic circular dichroism (ECD) and X-ray single crystal analyses. All isolated compounds were assayed for their anti-HIV-1IIIB activity. Compound 18 exhibited potent anti-HIV-1IIIB activity with an EC50 value of 1.32 μM (SI = 151.52).
Coronavirus Pandemic and The New Wave Theories The Way Forward.pdf
Creators: name: Enang, Agnes Ubana
Publisher: name: figshare
Year: 2022
Subjects: subject: 160205 Police Administration, Procedures and Practice
subject: FOS: Law
subject: 160599 Policy and Administration not elsewhere classified
subject: FOS: Political science
subject: 160509 Public Administration
subject: 160510 Public Policy

description: The reality of the Corona virus in our human affairs has become one of the most discussed phenomenon since the end of the second world war. This pandemic took the whole world by surprise. It came in a quiet and almost harmless manner like other pandemics like Ebola and Sars but quickly took the centre stage and halted attention in all the developmental facets of our national life. The depth and scope of its effects have left us in total confusion. This has led to the examination of the possible theories that have been put forward as reasons for its emergence. We have theories and counter theories, conspiracy theories and counter conspiracy theory and other constructivist theories to seek to present how to proceed in our discourse about the pandemic. We adopted the integrative Humanist theory as the most potent or viable theory for a reconstructivist position. Key words: Covid -19, Corona- virus, Pandemic, and Development
КОНСТИТУЦИОННЫЕ ГАРАНТИИ ПРАВА НА ТРУД В РЕСПУБЛИКЕ УЗБЕКИСТАН: МЕЖДУ ТЕОРИЕЙ И РЕАЛЬНОСТЬЮ
Creators: name: Турсунбаева, Рухшона
Publisher: name: Zenodo
Year: 2025

description: В данной статье рассматриваются конституционные гарантии права на труд в Республике Узбекистан, их законодательное развитие и проблемы практического применения. Особое внимание уделено личному опыту нарушения трудовых прав, который иллюстрирует разрыв между нормами права и реальной жизнью. Статья подчёркивает необходимость повышения правовой культуры среди граждан и совершенствования механизмов защиты их трудовых прав.
A phase III, open-label, multicenter study to evaluate the safety and efficacy of long-term triple combination therapy with azilsartan, amlodipine, and hydrochlorothiazide in patients with essential hypertension
Creators: name: Rakugi, Hiromi
name: Shimizu, Kohei
name: Nishiyama, Yuya
name: Sano, Yuhei
name: Umeda, Yuusuke
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: 60506 Virology

description: Purpose: Patients with essential hypertension who are receiving treatment with an angiotensin II receptor blocker and a calcium channel blocker often develop inadequate blood pressure (BP) control and require the addition of a diuretic. This study aimed to evaluate the long-term safety and efficacy of a triple combination therapy with 20 mg azilsartan (AZL), 5 mg amlodipine (AML) and 12.5 mg hydrochlorothiazide (HCTZ). Materials and methods: The phase III, open-label, multicenter study (NCT02277691) comprised a 4-week run-in period and 52-week treatment period. Patients with inadequate BP control despite AZL/AML therapy (n = 341) received 4 weeks’ treatment with AZL/AML (combination tablet) + HCTZ (tablet) and 4 weeks’ treatment with AZL/AML/HCTZ (combination tablet) in a crossover manner, followed by AZL/AML/HCTZ (combination tablet) from Week 8 of the treatment period up to Week 52. The primary and secondary endpoints were long-term safety and BP (office and home), respectively. Results: Most adverse events (AEs) were mild or moderate in intensity, and no deaths or treatment-related serious AEs were reported. The triple therapy provided consistent BP-lowering effects in both office and home measurements. Conclusions: The triple combination therapy with AZL/AML/HCTZ was well tolerated and effective for 52 weeks in Japanese patients with essential hypertension.
MPEC 2024-U184 : 2024 UU5
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 UU5

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.