cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Distributional limits to widespread and range-restricted species and their effects on species' abilities to respond to changes in climate and land use
Creators: name: Hierlihy, Catherine A
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: subject: Biology, Ecology.

description: The combination of climate change and anthropogenic land use changes are having a substantial effect on species' distributions worldwide. While climate change has led to range expansion in many areas, habitat loss and degradation are leading causes of extinction. It is therefore important to consider how these two forces are acting together to alter species distributions. Here, I have tested whether responses of butterfly species to climate change can be predicted based on range size and whether the level of human impact differs in areas where ranges have expanded and where they have collapsed. I found that the number of widespread species that have shifted their ranges north is not statistically different from the number of range-restricted species that have also shifted north. I also found that human impacts are greater in areas where ranges had collapsed than where they had expanded, and that this pattern was stronger for range-restricted species than for widespread ones. Butterfly species are not tracking changing climate in any predictable way with respect to range size, and are likely limited in their ability to do so by habitat losses.
What is the role of systematic reviews in tackling health inequity?
Creators: name: Welch, Vivian A
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Health Sciences, Public Health.
subject: Health Sciences, Health Care Management.

description: Introduction: Enhancing health equity remains of international political importance with endorsement from the World Health Assembly in 2009. The failure of systematic reviews to consider effects on health equity is described by decision-makers as a limitation to using systematic reviews as a basis for evidence-informed decisions. Hence, there is a need for guidance on the role of systematic reviews in assessing effects on health equity. Methods: Four studies were conducted to assess the role of systematic reviews in assessing effects on health equity. A Cochrane Collaboration methodology review and a methodology study assessed methods used in published systematic reviews to assess effects of interventions on health equity across ten categories defined by the acronym PROGRESS-Plus: Place of residence, Race/ethnicity, Occupation, Gender/sex, Religion, Education, Socioeconomic status, Social capital. Plus considers other factors associated with unequal opportunities for good health such as age, disability and developing country settings. A qualitative study assessed implementation factors that are associated with success of interventions in vulnerable populations and mapped these factors to the equity-effectiveness loop framework. An equity plausibility algorithm was developed and tested to predict the likelihood of effects of interventions on health equity. Results: Only 13% of published systematic reviews assess effects on health equity. Four methods were used to assess effects of interventions on health equity: 1) description of people in studies; 2) description of subgroup analyses; 3) analysis of differences; and 4) applicability assessment. Only lout of 20 methodological studies used an analytic method. Implementation factors that predict success of interventions on improving health of homeless people in Ottawa mapped well onto the equity effectiveness loop framework, suggesting this framework can be used to appraise and improve interventions to promote health equity. Testing of the equity plausibility algorithm developed based on these studies showed that 67% of respondents thought that differences in relative effects of interventions were likely across sex and socioeconomic status, but there was little to no inter-rater agreement for these judgments. Discussion: These studies show that systematic reviews lack consideration of effects of interventions on health equity. This dissertation makes recommendations to improve reporting and conduct of systematic reviews to improve the contribution of systematic reviews to the evidence-base on promoting health equity. Methodological research is needed to improve methods for assessing applicability of systematic reviews for populations across PROGRESS-Plus characteristics, by both those who conduct systematic reviews and those who use them as a basis for decision-making.
Caring for adult patients who die in the emergency department: Reflections of emergency room nurses
Creators: name: Hogan, Kerry-Anne
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Health Sciences, Nursing.

description: Background. Emergency room nurses work in an area in which the workload is unpredictable and chaotic. Treatment measures are usually aggressive and the goal of care in the emergency department is to restore physiological stability in a sick or injured person. As treatment measures usually occur quickly and nurses care for many patients throughout their shifts, there is often a lack of time to establish relationships with patients and/or family members. In a situation when treatment is needed immediately, there may not be enough time to discuss advanced directives with patients and/or family members. Although most patients are seen, treated and sent home or are admitted and recover, more than 7000 lives end in Canadian emergency departments each year (CIHI, 2006). Death in an emergency department is almost always considered a tragic event, regardless of whether the event was unexpected or expected. This view contrasts with the idealistic view of death occurring in a hospice or at home, free of pain and suffering and surrounded by loved ones. In an emergency department, treatment of critical illnesses and/or injuries begins immediately, leaving nurses or other members of the team little time to discuss advance directives or establish rapport with patients and/or family members. Purpose. The purpose of this research study was to improve our understanding of the experience of emergency room nurses when caring for an adult who dies in the emergency department.
The susceptibility of cell lines used in the production of human biologics to prion infection
Creators: name: LeBrun, Matthew P
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Biology, Molecular.
subject: Biology, Microbiology.
subject: Health Sciences, Immunology.

description: Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative human and animal disorders associated with the accumulation of pathogenic or abnormal prion protein (PrPSc) in the brain. Examples include scrapie in sheep and bovine spongiform encephalopathy (BSE) in cattle. Identifying and studying pathogenic prions in vitro has been hampered by a limited capacity to detect abnormal prion proteins and incomplete knowledge of cell lines capable of sustaining a prion infection. This study focused on determining the susceptibility of cells commonly used in the manufacturing process of biologics and biotherapeutics to prion infection and on development of an enrichment procedure that used trichloroacetic acid (TCA) precipitation to increase and confirm detection of PrPSc by Western blot. The newly optimized TCA precipitation protocol demonstrated a two- to four-fold increase in sensitivity compared to other precipitating techniques when used for Western blotting. Work indicated that Sf21, N2a, RmcB, CHO, HFF, HFF-MitC, PBDC, NAMALWA, MRC-5, HEK-293, U937 and Cos-7 cell lines were not susceptible to a PrPSc infection with BSE as the inoculant strain. N2a cells were susceptible to PrPSc when a liposome-based delivery system was used. The NIH/3T3 cell line was susceptible to a PrPSc infection. This work highlighted the need to test a variety of cell lines used in the production of human biologics for their susceptibility to prion infections. Although most of the cell lines tested did not demonstrate a sustained infection, the finding that NIH/3T3 cells were susceptible indicates that cell line origin and endogenous PrPSc amounts must not be the only factors that decide if a cell lines should be screened or tested.
Cold highly charged ions in a radio-frequency trap with superconducting magnetic shielding
Creators: name: Dijck, Elwin A.
name: Warnecke, Christian
name: Wehrheim, Malte
name: Henninger, Ruben B.
name: Eff, Julia
name: Georgiou, Kostas
name: Graf, Andrea
name: Kokh, Stepan
name: Sajith, Lakshmi P. Kozhiparambil
name: Mayo, Christopher
name: Schäfer, Vera M.
name: Volk, Claudia
name: Schmidt, Piet O.
name: Pfeifer, Thomas
name: López-Urrutia, José R. Crespo
Publisher: name: arXiv
Year: 2023
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We implement sympathetic cooling of highly charged ions (HCI) by fully enclosing a linear Paul trap within a superconducting radio-frequency resonator. A quantization magnetic field applied while cooling down into the superconducting state remains present in the trap for centuries and external electromagnetic fluctuations are greatly suppressed. A magnetic field decay rate at the 10$^{-10}$ s$^{-1}$ level is found using trapped Doppler-cooled Be$^+$ ions as hyperfine-structure (hfs) qubits. Ramsey interferometry and spin-echo measurements on magnetically-sensitive hfs transitions yield coherence times of >400 ms, showing excellent passive shielding at frequencies down to DC. For sympathetic cooling of HCI, we extract them from an electron beam ion trap (EBIT) and co-crystallize one together with Doppler-cooled Be$^+$ ions. By subsequently ejecting all but one Be$^+$ ions, we prepare single HCI for quantum logic spectroscopy towards frequency metrology and qubit operations with a great variety of HCI species.
description: 16 pages, 19 figures. The following article has been submitted to Review of Scientific Instruments. After it is published, it will be found at https://rsi.aip.org/
Le poids des représentations sociales: Les répercussions identitaires et sociales de mes expériences socioscolaires
Creators: name: Ruest-Paquette, Anne-Sophie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Education, Social Sciences.

description: Ce voyage autonarratif fait état des répercussions identitaires et sociales de mes expériences à titre de cible d'intimidation à l'école élémentaire (1986 à 1994) et secondaire (1994 à 1999), lesquelles étaient imbriquées des représentations sociales de la beauté féminine et des orientations sexuelles alternatives. La théorie de l'expérience de Dewey (1947/1968) en est l'encre puisqu'elle englobe tous les éléments qui sont essentiels à ma recherche: l'interaction et l'environnement social qui assurent la production, le développement et la reproduction des représentations sociales et des normes socioculturelles, l'expérience, dans laquelle s'inscrit l'intimidation, et la continuité de l'expérience qui renvoie aux processus que constituent la socialisation et la construction identitaire. Mes données (documents personnels, souvenirs, entretiens) ont fait l'objet d'une analyse de discours et témoignent de la multitude et de la complexité des enjeux liés à l'intimidation. Elles me permettent également d'approfondir notre compréhension du concept des marginalités multiples (Misa, 2006).
Optimum power allocation in V-BLAST with high-level modulation
Creators: name: Yu, Wei
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Engineering, Electronics and Electrical.

description: Optimal ordering procedure, which is computationally complex in the conventional vertical Bell-labs layered space-time (V-BLAST) algorithm, can be simplified. Among those low-complexity alternatives to the optimal ordering, non-uniform power allocation is intuitively attractive. The unified analysis of power optimized zero forcing (ZF) VBLAST proposed by prior work ([32]) is extended from BPSK to high-level modulations (also known as high-order modulations) by introducing a generic SER approximation---average union bound (AUB)---for multi-path fading channels. This AUB model represents SER by using two parameters related to the constellation---Ds, the normalized minimum Euclidean distance squared and Nc, the average number of the nearest constellation neighbors. First of all, the validity of AUB is demonstrated. Consequently, general average block error rate (BLER) of ZF-VBLAST can be approximated by a closed-form expression of D s and Nc for high-level modulation, the optimum power allocation solution are obtained at high and low SNR. The SNR gain and the robustness of this optimization are also rigorously defined and investigated in a generic manner. Additionally, the above performance variations related to the constellation size are discussed. At last, an efficient Monte Carlo simulation methodology, parallel MatlabRTM, is adopted for the simulations in this thesis. The observations of parallelism efficiency are summarized.
Holding Fast to Being Possible: Teaching as an Interpretive Practice
Creators: name: Markle, Joshua R
Publisher: name: Journal of Applied Hermeneutics
Year: 2020

description: This short piece is a response to the provocation, teaching is an interpretive practice. Below, I discuss why I believe teaching to be interpretive and point to aspects of my practice that I believe to be a rich source of insight.
description: Journal of Applied Hermeneutics, 2020: 2020
Extreme Bl Lacs At Multi-Tev Energies With The Cta
Creators: name: Galanti, Giorgio
name: Tavecchio, F.
name: Landoni, M.
name: Romano, P.
name: Vercellone, S.
name: For The CTA Consortium
Publisher: name: Zenodo
Year: 2018
Subjects: Active Galactic Nuclei
AGN
axion-like particles
BL Lacs
CTA

description: Extreme BL Lacs (EHBL) are a subclass of blazars with unique properties, such as synchrotron peaks in the hard X-ray band and extremely hard TeV spectra peaking above 10 TeV. Their exceptional properties make them interesting sources for current Cherenkov telescopes and a major topic for the upcoming Cherenkov Telescope Array (CTA), the next-generation ground-based γ-ray observatory. In particular, quite interesting is the possibility that, despite the strong γ-γ absorption, EHBL will be detected above 10 TeV. We explore the possibility that photon–axion-like particle oscillations give rise to an effective decrease of the opacity.
Developing an evidence-based reporting guideline for randomized controlled trial protocols: The SPIRIT Initiative
Creators: name: Tetzlaff, Jennifer Marie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Health Sciences, Epidemiology.

description: Protocols of randomized controlled trials (RCT) are important for many stakeholders including trialists, consumers, ethics boards, funding agencies and journal editors. However, RCT protocols often incompletely describe important trial details or describe inadequate methods. Biased methodological changes are also prevalent. This thesis' objective was to provide the evidence-base for the SPIRIT (Standard Protocol Items for RandomIzed T rials) Initiative, which aims to increase transparency by developing a reporting guideline for RCT protocols. Guideline content was developed and refined by: 1) a Delphi survey of key stakeholders and 2) a systematic review of empirical evidence. These two components yielded divergent yet complementary perspectives for concepts that RCT protocols should address. Cumulatively, 41 concepts related to trial methodology, administration/organization, ethics and dissemination were recommended for inclusion and 24 concepts for further discussion. These findings inform the SPIRIT guideline content and may ultimately help to improve protocol transparency and the validity of healthcare literature.
Economic Foundations For Creative Ageing Policy, Volume Ii
Creators: name: Klimczuk, Andrzej
Publisher: name: Zenodo
Year: 2017

description: This book shows that global population ageing is an opportunity to improve the quality of human life rather than a threat to economic competitiveness and stability. It describes the concept of the creative ageing policy as a mix of the silver economy, the creative economy, and the social and solidarity economy for older people. The second volume of Economic Foundations for Creative Ageing Policy focuses on the public policy and management concepts related to the use of the opportunities that are created by population ageing. Klimczuk covers theoretical analyses and case study descriptions of good practices to suggest strategies that could be internationally popularized. Each chapter includes exercises and assignments for both students and those who are likely to apply the presented concepts in practice. Contents: Foreword by Richard Adler Foreword by Dominic Campbell Introduction 1 The Politics of Ageing and the Challenges of Ageing Populations 2 Understanding Public Policy on Ageing 3 Sociological and Gerontological Perspectives on Ageing, Creativity, and the Third Age 4 Diversity of Ageing Policy Concepts 5 The Emergence of the Creative Ageing Movement 6 Aims and Challenges of the Creative Ageing Policy 7 Principles, Governance, and Coproduction of the Creative Ageing Policy 8 Organizational Forms and Management for the Building of Creative Capital of Older People Conclusion Afterword by Andreas Hoff and Kurt Lüscher Afterword by Suchandrima Chakraborty Afterword by Jorge Felix
L'Exil dans son labyrinthe, suivi de, Parcours théorique et réflexif sur la création littéraire
Creators: name: Andritoiu, Irina
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Literature, Modern.
subject: Literature, Canadian (French).

description: La première partie de ma thèse, L'Exil dans son labyrinthe, est un roman dont le but principal est de représenter un vécu qui se rattache à la perte du pays natal, d'une langue maternelle et d'une famille. J'ai donné vie à des personnages qui, du fait de la singularité de leurs parcours et de leurs va-et-vient entre deux pays et deux cultures, ont animé l'espace canado-roumain. Il s'agit d'un lieu de rencontre et de fusion entre principalement deux langues (le français et le roumain), entre le même et l'autre, et entre la parole et le silence. La deuxième partie de ma these comprend deux volets. Dans le premier, je mets en relief la notion d'autofiction à partir de la création du terme par Serge Doubrovsky en quatrième de couverture de son roman Fils, paru en 1977. Puis, je propose une réflexion sur la notion de " l'oubli ", qui débouche sur la figure polymorphe de l'étranger. Dans le deuxième volet, je réfléchis à ma démarche d'écriture, particulièrement à l'importance de la création dans le renouement avec le passé.
Keeping the faith: An exploratory analysis of faith-based arbitration in Ontario
Creators: name: Huth, Cathy
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Religion, General.
subject: Journalism.
subject: Law.
subject: Sociology, Criminology and Penology.

description: In 2003, the Islamic Institute of Civil Justice announced their intention of providing arbitration services to resolve family law disputes according to Islamic law. Concerned that such arbitration might be inconsistent with principles of equality and Ontario family law, many women's organizations and members of the public called on the government of Ontario to prohibit the use of arbitration based on religious law, in particular Islamic law. On September 11, 2005 the Government of Ontario announced that all family arbitration must be conducted in accordance with Ontario and Canadian law, thereby making faith-based arbitration awards non-enforceable. The purpose of this study is to explore the media's representation of faith-based arbitration in family law. A latent content analysis of Ontario newspaper articles was conducted to explore how the media portrayed the issue of faith-based arbitration. A sample of editorial, column, and opinion pieces from mainstream English Ontario newspapers published between December 13, 2003 and February 16, 2006 were selected. An analysis of the articles found common representations of women, immigrants and the Islamic faith, multiculturalism and religious freedom, and the justice system. More specifically, the findings from this study indicate that the media was misguided in defining the issue of faith-based arbitration. This occurred in one of three ways; either as faith-based arbitration exceeding the boundaries of multiculturalism, as eroding the secular state, or as contradicting the principle of one law for all. A second finding from this study was that much of the media coverage was alarmist and misinformed with strong signs of Islamophobia and the stereotyping of religious groups. As well, in accordance with Ayelet Shachar's (2001, 2005) view that multiculturalism is often portrayed as in conflict with women's equality rights, one of the major findings of this study is that the media depicted faith-based arbitration as a competition between women's equality rights and religious freedom (or multiculturalism). In conclusion, it is argued that the media's representation of faith-based arbitration was frequently misleading, alarmist, and uninformed. Although faith-based arbitration is conducted in other faith communities, the media coverage focussed primarily on the Muslim community, with stereotypes and alarmist rhetoric pervasive throughout the coverage. Indeed, there was a lack of knowledge about Islam, faith-based arbitration, and multiculturalism in the media's representation of faith-based arbitration.
Shedding a light on visual hallucinations in Parkinson's disease
Creators: name: Noordegraaf, Marina
Publisher: name: Zenodo
Year: 2020
Subjects: visual hallucinations
Parkinson's disease

description: This is the visual CC BY 4.0 interpretation and simplification by @Sparks4PD of the closed access article by Powell, A., Ireland, C., Lewis, S. (2020). Visual hallucinations and the role of medications in Parkinson's disease: Triggers, pathophysiology, and management. The journal of neuropsychiatry. DOI: https://doi.org/10.1176/appi.neuropsych.19110316 Apart from the poster/infographic, the 7 images which constitute the poster can be downloaded on its own as .png. The poster and/or images can be cited as indicated.
MUSER: A MUlti-Step Evidence Retrieval Enhancement Framework for Fake News Detection
Creators: name: Liao, Hao
name: Peng, Jiaohao
name: Huang, Zhanyi
name: Zhang, Wei
name: Li, Guanghua
name: Shu, Kai
name: Xie, Xing
Publisher: name: arXiv
Year: 2023
Subjects: subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: The ease of spreading false information online enables individuals with malicious intent to manipulate public opinion and destabilize social stability. Recently, fake news detection based on evidence retrieval has gained popularity in an effort to identify fake news reliably and reduce its impact. Evidence retrieval-based methods can improve the reliability of fake news detection by computing the textual consistency between the evidence and the claim in the news. In this paper, we propose a framework for fake news detection based on MUlti-Step Evidence Retrieval enhancement (MUSER), which simulates the steps of human beings in the process of reading news, summarizing, consulting materials, and inferring whether the news is true or fake. Our model can explicitly model dependencies among multiple pieces of evidence, and perform multi-step associations for the evidence required for news verification through multi-step retrieval. In addition, our model is able to automatically collect existing evidence through paragraph retrieval and key evidence selection, which can save the tedious process of manual evidence collection. We conducted extensive experiments on real-world datasets in different languages, and the results demonstrate that our proposed model outperforms state-of-the-art baseline methods for detecting fake news by at least 3% in F1-Macro and 4% in F1-Micro. Furthermore, it provides interpretable evidence for end users.
description: 12 pages, 5 figures, accepted by KDD '23, ADS track
Tous les points de vue du monde dans un seul journal? Ou la sélection des articles sur les pateras dans "Courrier international"
Creators: name: Totikaev, Isabelle
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Journalism.
subject: Language, General.

description: Translation is everywhere in the written press: journalists often select their topics from existing texts like newswire or newspaper articles. This thesis focuses on the selection of newspaper articles for re-publication, after they have been translated, in another newspaper, another country and for new readers. It includes an overall presentation of two important factors in the selection and the elimination of press articles: ideology and power relations among languages. Ideology is examined from four different points of view: ideology and society---that is the influence of society and the workplace on the journalist; personal ideology---that is the journalist's personal ideas and life experience; newspapers' ideology---that is the editorial policy and those who create it; and finally, ethics. Under examination as well are certain techniques that are frequently applied in newspaper translation and that affect text selection (adding, suppressing, contextualising). These may result in a new shorter article or in a "whole" translation. A French weekly newspaper, Courrier international, has been chosen as a case study, because it is made of translated articles from newspapers around the world. And the study focuses on one topic: pateras arriving on the Canary Islands in the summer of 2006, in other words, illegal immigrants leaving the coasts of Western Africa and Maghreb and heading for Spain. Three corpora are compared: the "local corpus" built on articles from six newspapers (two from Senegal, two from Algeria and two from Spain); the "French corpus" built on articles from two French newspapers; and the "translational corpus" built on articles from Courrier international.
Passive fault detection for FSM and EFSM models
Creators: name: Xu, Zhi
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Computer Science.

description: Passive fault detection is a fundamental part of passive testing which determines whether a system under test (SUT) is faulty by observing the input/output behaviors of the SUT without interfering with its normal operations. This thesis focuses on passive fault detection for SUTs whose specifications are given in finite state machine (FSM) and extended finite state machine (EFSM) models, and proposes a new approach to FSM and EFSM-based passive fault detection. Compared with previous approaches for FSM-based passive fault detection based on the approach in [Lee97], this proposed approach for FSM-based passive fault detection has better performance with respect to computational complexity and provides more information about possible starting state and possible trace during the passive fault detection without the need for additional post-processing. We analyzed the worst case time complexity of the algorithms and gave results of experiments to estimate the average case time complexity of these algorithms. This proposed approach for EFSM-based passive fault detection is derived from the proposed approach for FSM-based passive fault detection. It also provides information about possible starting state and possible trace at the end of passive fault detection; and utilizes a Hybrid method which combines the use of both Interval Refinement and Simplex methods for performance improvement during passive fault detection. Through experiments, we show that, compared with using only the Interval Refinement method or only the Simplex method, the Hybrid method guarantees the correctness of results with a reasonable time cost.
Isometries and the double copy
Creators: name: Easson, Damien A.
name: Herczeg, Gabriel
name: Manton, Tucker
name: Pezzelle, Max
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In the standard derivation of the Kerr-Schild double copy, the geodicity of the Kerr-Schild vector and the stationarity of the spacetime are presented as assumptions that are necessary for the single copy to satisfy Maxwell's equations. However, it is well known that the vacuum Einstein equations imply that the Kerr-Schild vector is geodesic and shear-free, and that the spacetime possesses a distinguished vector field that is simultaneously a Killing vector of the full spacetime and the flat background, but need not be timelike with respect to the background metric. We show that the gauge field obtained by contracting this distinguished Killing vector with the Kerr-Schild graviton solves the vacuum Maxwell equations, and that this definition of the Kerr-Schild double copy implies the Weyl double copy when the spacetime is Petrov type D. When the Killing vector is taken to be timelike with respect to the background metric, we recover the familiar Kerr-Schild double copy, but the prescription is well defined for any vacuum Kerr-Schild spacetime and we present new examples where the Killing vector is null or spacelike. While most examples of physical interest are type D, vacuum Kerr-Schild spacetimes are generically of Petrov type II. We present a straightforward example of such a spacetime and study its double copy structure. Our results apply to real Lorentzian spacetimes as well as complex spacetimes and real spacetimes with Kleinian signature, and provide a simple correspondence between real and self-dual vacuum Kerr-Schild spacetimes. This correspondence allows us to study the double copy structure of a self-dual analog of the Kerr spacetime. We provide evidence that this spacetime may be diffeomorphic to the self-dual Taub-NUT solution.
description: Typographical errors corrected, results unchanged
Inferring models of concurrent systems from logs of their behavior with CSight
Creators: name: Beschastnikh, Ivan
name: Brun, Yuriy
name: Ernst, Michael D.
name: Krishnamurthy, Arvind
Publisher: name: The University of British Columbia
Year: 2014

description: Concurrent systems are notoriously difficult to debug and understand. A common way of gaining insight into system behavior is to inspect execution logs and documentation. Unfortunately, manual inspection of logs is an arduous process, and documentation is often incomplete and out of sync with the implementation. To provide developers with more insight into concurrent systems, we developed CSight. CSight mines logs of a system’s executions to infer a concise and accurate model of that system’s behavior, in the form of a communicating finite state machine (CFSM). Engineers can use the inferred CFSM model to understand complex behavior, detect anomalies, debug, and increase confidence in the correctness of their implementations. CSight’s only requirement is that the logged events have vector timestamps. We provide a tool that automatically adds vector timestamps to system logs. Our tool prototypes are available at http://synoptic.googlecode.com/. This paper presents algorithms for inferring CFSM models from traces of concurrent systems, proves them correct, provides an implementation, and evaluates the implementation in two ways: by running it on logs from three different networked systems and via a user study that focused on bug finding. Our evaluation finds that CSight infers accurate models that can help developers find bugs.
title: 02_1853
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Development of offset locking based distributed sensor, and, Study of polarization effects in optical fibers
Creators: name: Chen, Ou
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Physics, Optics.

description: This thesis is composed of two main sections. The first section is the development of an optical fiber sensor. This new sensor system has been simulated by a Matlab program that considers the distributed feedback lasers' broader linewidth compared with that of frequency stabilized Nd:YAG lasers. The second section involves research on polarization effects in the optical fiber. In this thesis it is proven that only three states of polarization are required to determine the principle state of polarization vector. In addition, polarization effects in fiber Bragg gratings are investigated in this work. To measure the polarization dependent loss of the fiber Bragg grating for the reflection wavelength, an optical circulator is used. A problem arises since the circulator's polarization dependent loss contributes to the measurement result; this effect is often ignored. In this thesis, a test set has been developed to eliminate this uncertainty effect through a three-step procedure using the Jones Matrix method.
Phase separation in complex mixtures with many components: analytical expressions for spinodal manifolds
Creators: name: Bot, Arjen
name: van der Linden, Erik
name: Venema, Paul
Publisher: name: arXiv
Year: 2023
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: The phase behavior is investigated for systems composed of a large number of macromolecular components N, with N greater or equal to 2. Liquid-liquid phase separation is modelled using a virial expansion up to the second order of the concentrations of the components. Formal analytical expressions for the spinodal manifolds in N dimensions are derived that simplify their calculation (by transforming the original problem into inequalities that can be evaluated numerically using linear programming techniques). In addition, a new expression is obtained to calculate the critical manifold and the composition of the co-existing phases. The present analytical procedure complements previous attempts to handle spinodal decomposition for many components using a statistical approach based on Random Matrix Theory. The results are relevant for predicting effects of polydispersity on phase behavior in fields like polymer or food science, and to liquid-liquid phase separation in the cytosol of living cells.
description: 31 pages, 2 tables, 5 figures
GAP1(IP4BP)RASA3 mediates Galpha(i)-induced inhibition of mitogen-activated protein kinase in pituitary cells
Creators: name: Nafisi, Houman
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Biology, Neuroscience.

description: Activation of dopamine D2S receptor (short isoform) inhibits thyrotropin-releasing hormone (TRH)-stimulated p42/p44 mitogen-activated protein kinase (MAPK) phosphorylation in rat pituitary GH4ZR7 cells via Galphai3, but the underlying mechanism is not fully understood. To identify novel Galphai3 effectors we performed a yeast two-hybrid screen on cDNA library from GH4ZR7 cells using constitutively active Galphai3 as bait and identified RASA3. Galphai3-RASA3 interactions were confirmed using different approaches including yeast mating/beta-galactosidase assay, in vitro pull-down assay on bacterially expressed proteins, and co-immunoprecipitation with overexpressed or endogenous proteins in different mammalian cell lines. To address RASA3 function in dopamine D2S receptor-induced inhibition of MAPK activity endogenous RASA3 was suppressed in GH4ZR7 cells. In these clones D2S-mediated inhibition of TRH-induced phospho-MAPK was reversed by 70-80% compared to parental cells. Our results provide a novel mechanism for D2S-induced inhibition of MAPK and indicate that RASA3 links Galphai3 to inhibition of the powerful TRH-induced Ras/MAPK activation pathway.
title: Article_Première année de l'Annuaire pratique des jardiniers et cultivateurs
Creators: name: AmateurS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: ID_ARTI_00186
Macrophage-conditioned medium inhibits adipocyte differentiation
Creators: name: Constant, Vanessa Auguste
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Biology, Cell.

description: Obesity is accompanied by a reduced adipogenic capacity that promotes a dipocyte hypertrophy, low-grade inflammation, and insulin resistance. Macrophages infiltrate adipose tissue and may contribute to the low-grade inflammation associated with obesity and insulin resistance, suggesting that they could also play an anti-adipogenic role. I hypothesized that macrophage-secreted factors inhibit adipogenesis. My objectives were to assess if macrophage-conditioned medium (MacCM) inhibits adipocyte differentiation and to determine the mechanism by which the inhibition occurs. Murine J774 or human THP-1 MacCM was added to murine 3T3-L1 or human abdominal subcutaneous or omental preadipocytes. Either type of MacCM impaired murine and human adipogenesis as measured by triglyceride accumulation and protein expression of adipogenic markers. Time course studies revealed that THP-1-MacCM was required during the early phase of 3T3-L1 adipogenesis for its inhibitory effect. THP-1-MacCM stimulated the phosphorylation of ERK1/2 and IKKbeta in 3T3-L1 preadipocytes. Pharmacological inhibition of ERK1/2, with the specific MEK1 inhibitor PD98059, alleviated the inhibitory effect of THP-1-MacCM on TG accumulation. In conclusion, MacCM inhibits adipocyte differentiation in culture. The antiadipogenic effect depends on early exposure of THP-1-MacM to differentiating 3T3-L1 preadipocytes, and ERK1/2 is required for the inhibitory effect of THP-1-MacCM on TG accumulation.
SHP-1 differentially regulates LPS-mediated TNF-alpha and IL-10 production in murine splenic macrophages
Creators: name: Okenwa, Chinonso Chideraa
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Biology, Microbiology.

description: Host-Pathogen interactions are characterized by inflammatory responses, aimed at eliminating invading pathogens. During inflammatory responses, immune cells secrete cytokines and chemokines, with a broad range of immuno-regulatory roles. The role of the signaling protein, SHP-1 in regulating signaling pathways activated by cytokine, antigen and growth factor receptors has been studied for some time. However, the involvement of SHP-1 in the regulation of Lipopolysaccharide (LPS)-activated signal transduction pathways leading to cytokine production is less well understood. Loss of SHP-1 leads to development of complex inflammatory disorder(s). To understand the role of SHP-1 during the inflammation process, the SHP-1-deficient moth-eaten (me/me) mouse model was used to investigate LPS-induced TNF-alpha and IL-10 production, representing pro and anti-inflammatory cytokines, respectively. Results show that me/me splenic macrophages, when challenged with LPS in-vitro , secreted lower levels of IL-10 and concomitantly elevated TNF-alpha levels, compared to normal healthy littermate controls. Deregulated LPS-induced TNF-alpha and IL-10 production in SHP-1 deficient splenic macrophages were observed irrespective of LPS dose and time of stimulation as demonstrated by ELISA. These findings were further confirmed by RT-PCR, SHP-1 antisense experiments in normal splenic macrophages and adenoviral reconstitution of SHP-1 expression in me/me macrophages, suggesting a dual role of SHP-1 as a negative regulator of LPS induced TNF-alpha and a positive regulator of IL-10. To delineate the precise role of SHP-1 in regulating LPS-mediated IL-10 production, LPS-activated signaling proteins, which represent SHP-1 targets were examined. Results obtained established a role of p38 MAPK in LPS-mediated IL--10 secretion, but also demonstrate that P38 involvement is independent of SHP-1. Results of this study further reveals a role for tyrosine kinase Src and an adhesion molecule Pyk2 in SHP-1 dependent LPS-mediated IL-10 production and infer that optimal production of LPS-induced IL-10 requires an assembly of a signalosome, consisting of Src-Pyk2-SHP-1 proteins. In conclusion, we show for the first time that: SHP-1 is a positive regulator of LPS-induced IL-10 production in splenic macrophages and, LPS-mediated IL-10 production is governed by two distinct signaling pathways, only one of which is SHP-1 dependent.
Chloride ingress into reinforced concrete sustaining in-service loads
Creators: name: Deif, Amre Kamal
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Engineering, Civil.

description: The service life of a reinforced concrete (RC) bridge deck in cold climates is often limited by chloride-induced corrosion of the reinforcement due to exposure to de-icing salts routinely applied in the winter. Although there has been an extensive research effort on chloride ingress into concrete in the last three decades, research conducted on structural concrete members carrying in-service loads is limited. The objectives of this study were to investigate the effect of sustained load on chloride ingress into concrete and to examine the reliability of spraying a AgNO3 solution onto concrete as a quick method to determine chloride penetration. To achieve these objectives, an experimental program was carried out, in which a small-scale RC slab was subjected to wet and dry cycles with a saturated chloride solution while sustaining static service loads. The concrete slab was cast with three strips of different water-to-cement ratios to represent different field conditions. Supports were located to create both positive and negative moment regions in the top mat reinforcement of the slab. Concrete cores were taken at several sections along the RC deck, which were stressed to different levels, and at three time intervals, each of them after a wet/dry cycle of 90 days. Concrete cores were sprayed with a AgNO3 solution to determine an average chloride penetration front, and chloride profiles along the concrete cover for each core were measured by potentiometric titration. Chloride diffusion coefficients were obtained from the data obtained from spraying AgNO3 and titration, the latter by curve-fitting to Fick's 2nd law. The comparison between both sets of data reveals that the differences diminish as the time of exposure increases. The chloride diffusivity along the span of the slab, relative to that of an unstressed section, was related to the applied bending moment. The experimental results also indicate that there is a dependence of chloride ingress properties on the type and level of sustained load. An analysis of the data to study the effect of exposure time and water-to-cement ratio using colourimetric and potentiometric titration methods was also carried out.
Web services case study and implementation in financial industry
Creators: name: Wang, Juan
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Economics, General.
subject: Engineering, System Science.

description: Web services refer to a family of technologies that can universally standardize the communication of applications in order to connect systems, business partners, and customers cost-effectively through the World Wide Web. Web services will ease the constraints of time, cost, and space for discovering, negotiating, and conducting e-business transactions. As a result, they dramatically changed the way businesses design their applications as services, integrate with other business entities, manage business process workflows, and conduct e-business transactions. The purpose of this thesis is to investigate the current state of Web services technology and to evaluate the potential effectiveness of this technology for financial industry. By conducting several case studies, the advantages of Web services implementation are discussed, including financial areas and other related E-businesses. Non-technical aspects of Web services such as the value added, cost reduction, implementation contraction, project reusability, and business expanding are discussed as well. To demonstrate the use of Web services for financial industry, three Web service application prototypes were built within different domains relevant to international trading procedure. This simulation project is judged to be a successful demonstration of the potential applications of Web services for financial industry.
Crosstalk of E-cadherin and small GTPase Rap1 coordinates the clonality of human embryonic stem cells
Creators: name: Jezierski, Anna W
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Biology, Molecular.
subject: Biology, Microbiology.
subject: Health Sciences, Immunology.

description: Human embryonic stem cells (hESCs) are pluripotent cells, capable of giving rise to all three germ layers while maintaining their ability to proliferate indefinitely in culture. However, little is known regarding the microenvironmental cues that govern hESC self-renewal, particularly the challenge of clonal propagation following single cell dissociation. Increasing evidence suggests that intracellular pathways that coordinate E-cadherin-mediated cell-cell and integrin-mediated cell-ECM adhesions, are indispensable for the maintenance and self-renewal of hESCs. I have demonstrated that a potential crosstalk between small GTPase Rap1 and E-cadherin coordinates the colony formation and self-renewal of hESCs. I demonstrate that Rap1 expression kinetically decreases following the dissociation-induced disruption of E-cadherin mediated cell-cell adhesion compared to adherent hESCs. Inhibition of Rap1 with GGTI-298 completely abolishes the colony formation and self-renewal capacity of dissociated hESCs, whereas ectopic expression of Rap1 augments colony formation and survival. Addition of a potential activator of Rap1, Bombesin, inhibited dissociation-induced loss of Rap1 in hESCs and subsequently enhanced their survival, clonal propagation and self-renewal. Given the considerable extracellular and intracellular activators of Rap1, this work may provide an intracellular target to improve hESCs maintenance and self-renewal and provide new insights into the mechanisms regulating clonality and self-renewal.