cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(145) Thomas Hallows
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(146) John Hallows
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A spatial-temporal approach to surveillance of prostate cancer disparities in population subgroups.
Creators: name: Miller, Jerry A.
name: Nkhoma, Ella T.
name: Hsu, Chiehwen Ed
name: Mas, Francisco Soto
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: BACKGROUND: Prostate cancer mortality disparities exist among racial/ethnic groups in the United States, yet few studies have explored the spatiotemporal trend of the disease burden. To better understand mortality disparities by geographic regions over time, the present study analyzed the geographic variations of prostate cancer mortality by three Texas racial/ethnic groups over a 22-year period. METHODS: The Spatial Scan Statistic developed by Kulldorff et al was used. Excess mortality was detected using scan windows of 50% and 90% of the study period and a spatial cluster size of 50% of the population at risk. Time trend was analyzed to examine the potential temporal effects of clustering. Spatial queries were used to identify regions with multiple racial/ethnic groups having excess mortality. RESULTS: The most likely area of excess mortality for blacks occurred in Dallas-Metroplex and upper east Texas areas between 1990 and 1999; for Hispanics, in central Texas between 1992 and 1996: and for non-Hispanic whites, in the upper south and west to central Texas areas between 1990 and 1996. Excess mortality persisted among all racial/ethnic groups in the identified counties. The second scan revealed that three counties in west Texas presented an excess mortality for Hispanics from 1980-2001. Many counties bore an excess mortality burden for multiple groups. There is no time trend decline in prostate cancer mortality for blacks and non-Hispanic whites in Texas. CONCLUSION: Disparities in prostate cancer mortality among racial/ethnic groups existed in Texas. Central Texas counties with excess mortality in multiple subgroups warrant further investigation.
Novel Mining of Cancer via Mutation in Tumor Protein P53 using Quick Propagation Network
Creators: name: Ismaeel, Ayad Ghany
name: Yousif, Raghad Zuhair
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: FOS: Computer and information sciences

description: There is multiple databases contain datasets of TP53 gene and its tumor protein P53 which believed to be involved in over 50% of human cancers cases, these databases are rich as datasets covered all mutations caused diseases (cancers), but they haven't efficient mining method can classify and diagnosis mutations patient's then predict the cancer of that patient. This paper proposed a novel mining of cancer via mutations because there is no mining method before offers friendly, effective and flexible predict or diagnosis of cancers via using whole common database of TP53 gene (tumor protein P53) as dataset and selecting a minimum number of fields in training and testing quick propagation algorithm which supporting this miming method. Simulating quick propagation network for the train dataset shows results the Correlation (0.9999), R-squared (0.9998) and mean of Absolute Relative Error (0.0029), while the training for the ALL datasets (train, test and validation dataset) have results the Correlation (0.9993), R-squared (0.9987) and mean of Absolute Relative Error (0.0057).
description: 6 Pages, 9 figures, 2 Table
title:  T: Textbooks
Creators: name: Kalmi, Panu
Publisher: name: Roma TrE-Press
Year: 2016

description: Questo capitolo focalizza la sua attenzione su un tema assai rilevante nel dibattito teorico e non solo: i manuali di economia trascurano le imprese cooperative rispetto a quelle capitalistiche? A quanto pare sembrerebbe proprio di si  e questo pur rappresentando  le cooperative da più di 150 anni, una parte importante delle economie di mercato. Nonostante questo, la maggior dei libri di testo di economia scritti dal secondo dopoguerra in poi, diversamente da quanto avveniva agli inizi del ventesimo secolo, prestano poca attenzione alle imprese cooperative.
description: The co-operative firm. Keywords
Relationships and communication in minority participation in research: multidimensional and multidirectional.
Creators: name: Estroff, Sue E.
name: Corbie-Smith, Giselle
name: Williams, Ishan Canty
name: Dorrance, Jessica
name: Blumenthal, Connie
name: Henderson, Gail
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: We examined the range and nature of investigators' communication and relationship building as they recruit minority participants in their research. Semistructured, in-depth interviews were conducted with 33 investigators conducting research with human participants. The response rate was 77%. Investigators described several kinds of relationships that are formed or called upon when including minority participants in research. The relationships ranged from study-related, short-term interactions geared solely to facilitate recruitment to others that were longer term, extending beyond a particular project. The data suggest that a range of relationships is important as investigators seek to include minority populations in research. These relationships can both facilitate the recruitment process as well as aid in the interpretation of research findings.
Modular Hamiltonian of Excited States in Conformal Field Theory
Creators: name: Lashkari, Nima
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We present a novel replica trick that computes the relative entropy of two arbitrary states in conformal field theory. Our replica trick is based on the analytic continuation of partition functions that break the replica Z_n symmetry. It provides a method for computing arbitrary matrix elements of the modular Hamiltonian corresponding to excited states in terms of correlation functions. We show that the quantum Fisher information in vacuum can be expressed in terms of two-point functions on the replica geometry. We perform sample calculations in two-dimensional conformal field theories.
description: 5 pages, 1 figure
An OpenCL-based Monte Carlo dose calculation engine (oclMC) for coupled photon-electron transport
Creators: name: Tian, Zhen
name: Shi, Feng
name: Folkerts, Michael
name: Qin, Nan
name: Jiang, Steve B.
name: Jia, Xun
Publisher: name: arXiv
Year: 2015
Subjects: subject: Medical Physics (physics.med-ph)
subject: FOS: Physical sciences

description: Monte Carlo (MC) method has been recognized the most accurate dose calculation method for radiotherapy. However, its extremely long computation time impedes clinical applications. Recently, a lot of efforts have been made to realize fast MC dose calculation on GPUs. Nonetheless, most of the GPU-based MC dose engines were developed in NVidia CUDA environment. This limits the code portability to other platforms, hindering the introduction of GPU-based MC simulations to clinical practice. The objective of this paper is to develop a fast cross-platform MC dose engine oclMC using OpenCL environment for external beam photon and electron radiotherapy in MeV energy range. Coupled photon-electron MC simulation was implemented with analogue simulations for photon transports and a Class II condensed history scheme for electron transports. To test the accuracy and efficiency of our dose engine oclMC, we compared dose calculation results of oclMC and gDPM, our previously developed GPU-based MC code, for a 15 MeV electron beam and a 6 MV photon beam on a homogenous water phantom, one slab phantom and one half-slab phantom. Satisfactory agreement was observed in all the cases. The average dose differences within 10% isodose line of the maximum dose were 0.48-0.53% for the electron beam cases and 0.15-0.17% for the photon beam cases. In terms of efficiency, our dose engine oclMC was 6-17% slower than gDPM when running both codes on the same NVidia TITAN card due to both different physics particle transport models and different computational environments between CUDA and OpenCL. The cross-platform portability was also validated by successfully running our new dose engine on a set of different compute devices including an Nvidia GPU card, two AMD GPU cards and an Intel CPU card using one or four cores. Computational efficiency among these platforms was compared.
description: page line has been removed
Bath induced coherence and the secular approximation
Creators: name: Eastham, P. R.
name: Kirton, P.
name: Cammack, H. M.
name: Lovett, B. W.
name: Keeling, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Finding efficient descriptions of how an environment affects a collection of discrete quantum systems would lead to new insights into many areas of modern physics. Markovian, or time-local, methods work well for individual systems, but for groups a question arises: does system-bath or inter-system coupling dominate the dissipative dynamics? The answer has profound consequences for the long-time quantum correlations within the system. We consider two bosonic modes coupled to a bath. By comparing an exact solution to different Markovian master equations, we find that a smooth crossover of the equations-of-motion between dominant inter-system and system-bath coupling exists -- but requires a non-secular master equation. We predict a singular behaviour of the dynamics, and show that the ultimate failure of non-secular equations of motion is essentially a failure of the Markov approximation. Our findings justify the use of time-local theories throughout the crossover between system-bath dominated and inter-system-coupling dominated dynamics.
description: 10 pages, 3 figures. v2: improved introduction, added analysis of positivity, corrected typos. v3: corrected typos in eqs. 5 and 23
title:  U: United Nations and Co-operatives
Creators: name: Henrÿ  ,  Hagen
Publisher: name: Roma TrE-Press
Year: 2016

description: Questo capitolo fornisce un interessante contributo per una migliore comprensione della relazione tra il settore cooperativo e le Nazioni Unite. L'interazione tra Nazioni Unite e le cooperative ha una lunga e variegata storia che in questo capitolo viene ripercorsa con una particolare attenzione verso ILO e FAO. In particolare, negli ultimi 20 anni, tre strumenti internazionali sono stati adotatti: la dichiarazione iCA sull’identità cooeprativa; le linee guida ONU sulle cooperative; la raccomandazione ILO numero 193 sulla promozione delle cooperative.
description: The co-operative firm. Keywords
When race matters: disagreement in pain perception between patients and their physicians in primary care.
Creators: name: Staton, Lisa J.
name: Genao, Inginia
name: Panda, Mukta
name: Cykert, Sam
name: Carey, Tim
name: O'Rorke, Jane
name: Faeslis, Charles
name: Rosenberg, Eric
name: Kurz, James
name: Mechaber, Alex J.
name: Wood, JoAnn
name: Calleson, Diane
name: Pasanen, Mark
name: Menon, Madhusudan
name: Chen, Ian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Patients and physicians often disagree in their assessment of pain intensity. This study explores the impact of patient factors on underestimation of pain intensity in chronic noncancer pain. We surveyed patients and their physicians in 12 primary care centers. To measure pain intensity, patients completed an 11-point numeric rating scale for which pain scores range from 0 (no pain) to 10 (unbearable pain). Physicians rated patients' pain on the same scale. We defined disagreement of pain intensity as underestimation or overestimation by 22 points. Of 601 patients approached, 463 (77%) completed the survey. The majority of participants were black (39%) or white (47%), 67% were female, and the mean age was 53 years. Physicians underestimated pain intensity relative to their patients 39% of the time. Forty-six percent agreed with their patients' pain perception, and 15% of physicians overestimated their patients' pain levels by > or =2 points. In both the bivariate and multivariable models, black race was a significant variable associated with underestimation of pain by physicians (p < 0.05; OR = 1.92; 95% CI: 1.31-2.81). This study finds that physicians are twice as likely to underestimate pain in blacks patients compared to all other ethnicities combined. A qualitative study exploring why physicians rate blacks patients' pain low is warranted.
(143) Thomas McEwen
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(144) Hallows
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Wertheim perturbation theory: thermodynamics and structure of patchy colloids
Creators: name: Fantoni, Riccardo
name: Pastore, Giorgio
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We critically discuss the application of the Wertheim's theory to classes of complex associating fluids that can be today engineered in the laboratory as patchy colloids and to the prediction of their peculiar gas-liquid phase diagrams. Our systematic study, stemming from perturbative version of the theory, allows us to show that, even at the simplest level of approximation for the inter-cluster correlations, the theory is still able to provide a consistent and stable picture of the behavior of interesting models of self-assembling colloidal suspension. We extend the analysis of a few cases of patchy systems recently introduced in the literature. In particular, we discuss for the first time in detail the consistency of the structural description underlying the perturbative approach and we are able to prove a consistency relationship between the valence as obtained from thermodynamics and from the structure for the one-site case. A simple analytical expression for the structure factor is proposed.
description: 25 pages, 10 figures
Predictors of Hearing Aid Use Time in Children With Mild-to-Severe Hearing Loss
Creators: name: Moeller, Mary Pat
name: Walker, Elizabeth
name: Oleson, Jacob
name: Spratford, Meredith
name: Jacobs, Shana
name: Ou, Hua
name: Roush, Patricia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Purpose—This study investigated predictors of hearing aid (HA) use time for children with mild-severe hearing loss. Barriers to consistent HA use and reliability of parent report measures were also examined. Method—Participants included parents of 272 children with hearing loss. Parents estimated the amount of time the child used HAs daily. Regression analysis examined the relationships among independent variables and HA use time. To determine parental accuracy of HA use time, datalogging from the HA was compared to parental estimates. Results—Longer HA use related to older age, poorer hearing, and higher maternal education. Parental consistency ratings revealed similar findings; younger children and children with milder hearing losses wore HAs less consistently than older children and children with more severe hearing loss. Parents’ estimates and datalogging were significantly correlated; however, results suggested parents overestimate the amount of time their children wear their hearing aids. Conclusions—The findings provide evidence that certain variables were significantly related to the amount of time children wore their HAs. Consistency rating scales provided insight into circumstances that were challenging for families. Use of both parental reports and datalogging may allow clinicians and researchers to obtain a general estimate of HA use time.
(142) John McEwen
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A transversal approach for patch-based label fusion via matrix completion
Creators: name: Guo, Yanrong
name: Thung, Kim-Han
name: Wu, Guorong
name: Shen, Dinggang
name: Sanroma, Gerard
name: Gao, Yaozong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Recently, multi-atlas patch-based label fusion has received an increasing interest in the medical image segmentation field. After warping the anatomical labels from the atlas images to the target image by registration, label fusion is the key step to determine the latent label for each target image point. Two popular types of patch-based label fusion approaches are (1) reconstruction-based approaches that compute the target labels as a weighted average of atlas labels, where the weights are derived by reconstructing the target image patch using the atlas image patches; and (2) classification-based approaches that determine the target label as a mapping of the target image patch, where the mapping function is often learned using the atlas image patches and their corresponding labels. Both approaches have their advantages and limitations. In this paper, we propose a novel patch-based label fusion method to combine the above two types of approaches via matrix completion (and hence, we call it transversal). As we will show, our method overcomes the individual limitations of both reconstruction-based and classification-based approaches. Since the labeling confidences may vary across the target image points, we further propose a sequential labeling framework that first labels the highly confident points and then gradually labels more challenging points in an iterative manner, guided by the label information determined in the previous iterations. We demonstrate the performance of our novel label fusion method in segmenting the hippocampus in the ADNI dataset, subcortical and limbic structures in the LONI dataset, and mid-brain structures in the SATA dataset. We achieve more accurate segmentation results than both reconstruction-based and classification-based approaches. Our label fusion method is also ranked 1st in the online SATA Multi-Atlas Segmentation Challenge.
Dependency of image quality on system configuration parameters in a stationary digital breast tomosynthesis system
Creators: name: Lu, Jianping
name: Tucker, Andrew W.
name: Zhou, Otto
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Purpose: In principle, a stationary digital breast tomosynthesis (s-DBT) system has better image quality when compared to continuous motion DBT systems due to zero motion blur of the source. The authors have developed a s-DBT system by using a linear carbon nanotube x-ray source array. The purpose of the current study was to quantitatively evaluate the performance of the s-DBT system;and investigate the dependence of imaging quality on the system configuration parameters. Methods: Physical phantoms were used to assess the image quality of each configuration including inplane resolution as measured by the modulation transfer function (MTF), inplane contrast as measured by the signal difference to noise ratio (SdNR), and depth resolution as measured by the z-axis artifact spread function. Five parameters were varied to create five groups of configurations: (1) total angular span; (2) total number of projection images; (3) distribution of exposure (mAs) across the projection images; (4) entrance dose; (5) detector pixel size. Results: It was found that the z-axis depth resolution increased with the total angular span but was insensitive to the number of projection images, mAs distribution, entrance dose, and detector pixel size. The SdNR was not affected by the angular span or the number of projection images. A decrease in SdNR was observed when the mAs was not evenly distributed across the projection images. As expected, the SdNR increased with entrance dose and when larger pixel sizes were used. For a given detector pixel size, the inplane resolution was found to be insensitive to the total angular span, number of projection images, mAs distribution, and entrance dose. A 25% increase in the MTF was observed when the detector was operating in full resolution mode (70 μm pixel size) compared to 2 × 2 binned mode (140 μm pixel size). Conclusions: The results suggest that the optimal imaging configuration for a s-DBT system is a large angular span, an intermittent number of projection views, and a uniform mAs distribution over all views. With the detector operating at full resolution, a stationary DBT system can achieve an inplane resolution of 5.1 cycles per mm, which is significantly better than continuous motion DBT systems.
Neighborhood Design and Perceptions: Relationship with Active Commuting
Creators: name: EVENSON, KELLY
name: MCKENZIE, THOMAS
name: DOWDA, MARSHA
name: RUNG, ARIANE
name: VOORHEES, CAROLYN
name: SIRARD, JOHN
name: ASHWOOD, SCOTT
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Purpose—Walking to and from school contributes to total physical activity levels. This study investigated whether perceived and actual neighborhood features were associated with walking to or from school among adolescent girls. Methods—A sample of geographically diverse 8th grade girls (N=890) from the Trial for Activity in Adolescent Girls (TAAG) study living within 1.5 miles of their middle school were recruited. Participants completed a self-administered survey on their neighborhood and walking behavior. Geographic information system (GIS) data were used to assess objective neighborhood features. Nested multivariable logistic regression analyses were conducted to determine the contribution of perceived and objective measures of walking to or from school. Results—Fifty-six percent (N=500) of the girls walked to or from school at least one day of the week. White (42%) girls walked more frequently than Hispanic (25%) and African American (21%) girls. Girls were nearly twice as likely to walk to or from school if they perceived their neighborhoods as safe and perceived they had places they liked to walk, controlling for other potential confounders. Additionally, girls who lived closer to school, had more active destinations in their neighborhood, and smaller sized blocks were more likely to walk to or from school than those who did not. Conclusion—Safety, land use, and school location issues need to be considered together when designing interventions to increase walking to and from school.
title:  V: Venture Capital for Co-operatives
Creators: name: Di Cecco, Giustino
Publisher: name: Roma TrE-Press
Year: 2016

description: V (VENTURE CAPITAL FOR CO-OPERATIVES), di Giustino Di Cecco, evidenzia i sorprendenti dati italiani del finanziamento di rischio alla imprese cooperative. Nonostante la scarsa diffusione, sia culturale che economica, del venture capitalin Italia, lo sviluppo delle modalità di reperimento di capitale di rischio da parte delle società cooperative si deve ad una sorprendente intuizione normativa del legislatore del 1992 e alla successiva attuazione della mutualità di sistema. Da leggere insieme ai capitoli paragrafi A, F ed L.
description: The co-operative firm. Keywords
Assessment of Adherence to the Practice Guideline of High Alert Drugs for Inpatient Department: Case Study at a Community Hospital in Central Region
Creators: name: Wimonluk Ruangwattanachok
Publisher: name: Faculty of Pharmaceutical Sciences KKU MSU UBU
Year: 2018
Subjects: high alert drug, guideline of high alert drug

description: Isan Journal of Pharmaceutical Sciences, 14, 4, 18-28
Evidence for phenotypic bistability resulting from transcriptional interference of bvgAS in Bordetella bronchiseptica: Phenotypic bistability inBordetella
Creators: name: Mason, Eliza
name: Scheller, Erich
name: Henderson, Michael
name: Cotter, Peggy
name: Byrd, Matthew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Bordetella species cause respiratory infections in mammals. Their master regulatory system BvgAS controls expression of at least three distinct phenotypic phases in response to environmental cues. The Bvg+ phase is necessary and sufficient for respiratory infection while the Bvg− phase is required for survival ex vivo. We obtained large colony variants (LCVs) from the lungs of mice infected with B. bronchiseptica strain RBX9, which contains an in-frame deletion mutation in fhaB, encoding filamentous hemagglutinin. RBX9 also yielded LCVs when switched from Bvg− phase conditions to Bvg+ phase conditions in vitro. We determined that LCVs are composed of both Bvg+ and Bvg− phase bacteria and that they result from defective bvgAS positive autoregulation. The LCV phenotype was linked to the presence of a divergent promoter 5′ to bvgAS, suggesting a previously undescribed mechanism of transcriptional interference that, in this case, leads to feedback-based bistability (FBM). Our results also indicate that a small proportion of RBX9 bacteria modulates to the Bvg− phase in vivo. In addition to providing insight into transcriptional interference and FBM, our data provide an example of an in-frame deletion mutation exerting a ‘polar’ effect on nearby genes.
The Evaluation of Employers' Satisfaction towards the Desirable Characteristics of the Pharmacy Graduates, Ubon Ratchathani University
Creators: name: Pichaya Pimrin
Publisher: name: Faculty of Pharmaceutical Sciences KKU MSU UBU
Year: 2018
Subjects: Employers' satisfaction, 5-year BPharm program, 6-year PharmD program, Desirable characteristics, Pharmacy graduates

description: Isan Journal of Pharmaceutical Sciences, 14, 4, 29-37
Efficacy and Safety of Long-term Prophylaxis in Severe Hemophilia A Dogs Following Liver Gene Therapy Using AAV Vectors
Creators: name: Altynova, Ekaterina
name: Franck, Helen
name: Sarkar, Rita
name: Sabatino, Denise
name: Merricks, Elizabeth
name: Zhou, Shangzhen
name: Arruda, Valder
name: Kazazian Jr, Haig
name: Nichols, Timothy
name: Lange, Amy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Developing adeno-associated viral (AAV)–mediated gene therapy for hemophilia A (HA) has been challenging due to the large size of the factor VIII (FVIII) complementary DNA and the concern for the development of inhibitory antibodies to FVIII in HA patients. Here, we perform a systematic study in HA dogs by delivering a canine FVIII (cFVIII) transgene either as a single chain or two chains in an AAV vector. An optimized cFVIII single chain delivered using AAV serotype 8 (AAV8) by peripheral vein injection resulted in a dose-response with sustained expression of FVIII up to 7% (n = 4). Five HA dogs administered two-chain delivery using either AAV8 or AAV9 via the portal vein expressed long-term, vector dose–dependent levels of FVIII activity (up to 10%). In the two-chain approach, circulating cFVIII antigen levels were more than fivefold higher than activity. Notably, no long-term immune response to FVIII was observed in any of the dogs (1/9 dogs had a transient inhibitor). Long-term follow-up of the dogs showed a remarkable reduction (>90%) of bleeding episodes in a combined total of 24 years of observation. These data demonstrate that both approaches are safe and achieve dose-dependent therapeutic levels of FVIII expression, which supports translational studies of AAV-mediated delivery for HA.
Künstliche Intelligenz und betriebliche Mitbestimmung. Herausforderungen und Handlungsmöglichkeiten für Arbeitnehmer*innenvertretungen
Creators: name: Köhne, Sonja
name: von Richthofen, Georg
name: Send, Hendrik
Publisher: name: Zenodo
Year: 2023
Subjects: Künstliche Intelligenz
Mitbestimmung
Zukunft der Arbeit
Artificial Intelligence
Work Representation
Future of Work

description: Künstliche Intelligenz (KI) verändert die Arbeitswelt und wirft dabei neue Fragen für die Mitbestimmung auf. Ziel dieses Diskussionspapier ist es, Herausforderungen und konkrete Handlungsmöglichkeiten für betriebliche und gewerkschaftliche Mitbestimmungsakteur*innen zu skizzieren, um einen beschäftigtenorientierten Einsatz von KI zu fördern. Hierzu stützen wir uns auf die Erkenntnisse aus einem Workshop mit 26 Vertreter*innen aus dem Bereich der Mitbestimmung. Im Vorfeld haben wir Fallstudien mit Unternehmen, die KI-basierte Systeme einsetzen, sowie Interviews mit Mitbestimmungsakteur*innen durchgeführt. Im Rahmen des Workshops haben die Teilnehmenden dann vier zentrale Handlungsfelder der Verhandlung von KI diskutiert, die wir als Informieren, Evaluieren, Vereinbaren und Mobilisieren bezeichnen. Wahrgenommene Herausforderungen innerhalb dieser Handlungsfelder beziehen sich u.a. auf eine fehlende Definition von KI, unzureichende Informationen zu KI-Vorhaben und eine mangelnde Vorhersehbarkeit der konkreten Auswirkungen von KI. Aktuell waren sich die Teilnehmenden jedoch auch uneinig hinsichtlich einiger Fragen zur Verhandlung von KI. Diese Unsicherheit stellt eine weitere Herausforderung für die Vertretung der Interessen der Beschäftigten dar und betrifft z. B. die notwendige zentrale Steuerung (Wie lassen sich unternehmensweite KI-Projekte zentral überblicken?), das erforderliche technische Verständnis (Inwieweit müssen Betriebsrät*innen KI-Technologien technisch verstehen?) und die Bewertung (Wie sind die Auswirkungen von KI zu bewerten?). Den skizzierten Herausforderungen begegnen Arbeitnehmer*innenvertretungen, indem sie sich u.a. vernetzen (z. B. mit anderen Betriebsrät*innen), die Verhandlungen systematisieren (z. B. durch Checklisten) und flexibilisieren (z. B. durch Pilotprojekte).
title:  W: War, Co-Operatives and Post-Conflict in Colombia
Creators: name: Dulcey Martínez, Germán Ricardo
Publisher: name: Roma TrE-Press
Year: 2016

description: This chapter describes the role of the Colombian co-operative sector in conflict areas and during the peace process. The experiences described and the conclusions drawn are relevant to many developing countries and conflict areas worldwide.
Este capítulo describe el rol del sector coperativo colombiano en las áreas de conflicto y durante el proceso de paz. Las experiencias descritas y las conclusiones presentadas son relevantes para muchos países en desarrollo y zonas de conflicto alrededor del mundo.
description: The co-operative firm. Keywords
Mutant-specific gene expression profiling identifies SRY-related HMG box 11b (SOX11b) as a novel regulator of vascular development in zebrafish
Creators: name: Schmitt, Christopher
name: Woolls, Melissa
name: Jin, Suk-Won
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Previous studies have identified two zebrafish mutants, cloche and groom of cloche, which lack the majority of the endothelial lineage at early developmental stages. However, at later stages, these avascular mutant embryos generate rudimentary vessels, indicating that they retain the ability to generate endothelial cells despite this initial lack of endothelial progenitors. To further investigate molecular mechanisms that allow the emergence of the endothelial lineage in these avascular mutant embryos, we analyzed the gene expression profile using microarray analysis on isolated endothelial cells. We find that the expression of the genes characteristic of the mesodermal lineages are substantially elevated in the kdrl+ cells isolated from avascular mutant embryos. Subsequent validation and analyses of the microarray data identifies Sox11b, a zebrafish ortholog of SRY-related HMG box 11 (SOX11), which have not previously implicated in vascular development. We further define the function sox11b during vascular development, and find that Sox11b function is essential for developmental angiogenesis in zebrafish embryos, specifically regulating sprouting angiogenesis. Taken together, our analyses illustrate a complex regulation of endothelial specification and differentiation during vertebrate development.
(138) Beatrice McEwen
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title:  Z: Zeitgeist, Educating Diversity
Creators: name: Bernardi, Andrea
name: Monni, Salvatore
Publisher: name: Roma TrE-Press
Year: 2016

description: In questo capitolo l’attenzione degli autori si concentra sulle imprese cooperative intese come istituzioni. Le imprese cooperative come tutte le istituzioni per funzionare bene devono necessariamente essere in sintonia con lo Zeitgeist,   lo spirito del tempo. Essere in sintonia con lo spirito del tempo significa innanzitutto che l'identità del settore cooperativo, i suoi obiettivi come le diversità rispetto alle imprese capitaliste concorrenti, siano periodicamente messe in discussione per fare in modo che si adattino alle esigenze contemporanee.
description: The co-operative firm. Keywords
Insulin-like growth factor-I ameliorates demyelination induced by tumor necrosis factor-α in transgenic mice
Creators: name: Ye, Ping
name: Kollias, George
name: D'Ercole, A. Joseph
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Our laboratories have reported that TNF-α causes myelin damage and apoptosis of oligodendrocytes and their precursors in vitro and in vivo. We also have reported that IGF-I can protect cultured oligodendrocytes and their precursors from TNF-α-induced damage. In this study, we investigated whether IGF-I can protect oligodendrocytes and myelination from TNF-α-induced damage in vivo by cross-breeding TNF-α transgenic (Tg) mice with IGF-I Tg mice that overexpress IGF-I exclusively in brain. At 8 weeks of age, compared to wildtype (WT) mice, the brain weights of TNF-α Tg mice were decreased by ~20%, while those of IGF-I Tg mice were increased by ~20%. The brain weights of mice that carry both TNF-α and IGF-I transgenes (TNF-α/IGF-I Tg mice) did not differ from WT mice. As judged by histochemical staining and immunostaining, myelin content in the cerebellum of TNF-α/IGF-I Tg mice was similar to that in WT mice and much more than that in TNF-α Tg mice. Consistently, western immunoblot analysis showed that myelin basic protein abundance in the cerebellum of TNF-α/IGF-I Tg mice was double that in TNF-α Tg mice. Compared to WT mice, the number of oligodendrocytes was decreased by ~36% in TNF-α Tg mice, while it was increased in IGF-I Tg mice by ~40%. Oligodendrocyte number in TNF-α/IGF-I Tg mice was almost as twice many as that in TNF-α Tg mice. Furthermore, IGF-I overexpression significantly reduced TNF-α-induced increases in apoptotic cell number, active caspase-3 abundance and degraded MBP. Our results indicate that IGF-I is capable of protecting myelin and oligodendrocytes from TNF-α-induced damage in vivo.
Additivity of the ideal of microscopic sets
Creators: name: Kwela, Adam
Publisher: name: arXiv
Year: 2015
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics

description: A set $M\subset\mathbb{R}$ is microscopic if for each $\varepsilon>0$ there is a sequence of intervals $(J_n)_{n\inω}$ covering $M$ and such that $|J_n|\leq \varepsilon^{n+1}$ for each $n\inω$. We show that there is a microscopic set which cannot be covered by a sequence $(J_n)_{n\inω}$ with $\{n\inω:J_n\neq\emptyset\}$ of lower asymptotic density zero. We prove (in ZFC) that additivity of the ideal of microscopic sets is $ω_1$. This solves a problem of G. Horbaczewska. Finally, we discuss additivity of some generalizations of this ideal.
Pseudoscalar mesons with symmetric bound state vertex functions on the light front
Creators: name: Yabusaki, George H. S.
name: Ahmed, Ishtiaq
name: Paracha, M. Ali
name: de Melo, J. P. B. C.
name: El-Bennich, Bruno
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the electromagnetic form factors, decay constants and charge radii of the pion and kaon within the framework of light-front field theory formalism where we use an ansatz for the quark-meson interaction bound-state function which is symmetric under exchange of quark and antiquark momentum. The above mentioned observables are evaluated for the $+$ component of the electromagnetic current, $J^+$, in the Breit frame. We also check the invariance of these observables in other frames, whereby both the valance and the non-valence contributions have to be taken into account, and study the sensitivity of the electromagnetic form factors and charge radius to the model's parameters; namely, the quark masses, $m_u=m_d$, $m_{\bar s}$, and the regulator mass, $m_R$. It is found that after a fine tuning of the regulator mass, i.e. $m_R=0.6$ GeV, the model is suitable to fit the available experimental data within the theoretical uncertainties of both the pion and kaon.
description: 8 pages, 8 figures, use revtex, submitted to Phy. Rev. D (2015)
Assessing the quality and results of meta-analyses on crop diversification Protocol for systematic review and evidence map
Creators: name: Beillouin, Damien
name: Ben-Ari, Tamara
name: Makoswki, David
Publisher: name: Zenodo
Year: 2020
Subjects: systematic review, crop diversification, catch crop, agroforestry, species mixture, rota-tion, cover crops, intercropping, buffer strips, trap crops

description: Diversified agriculture is often presented as a major lever to improve the sustainabilityof agroecosystems. Of particular interest, is the productivity and economic performance ofthese systems as well as the associated environmental impacts. A multifunctional assessmentof the potential benefits of diversified agriculture is thus essential. Several meta-analysessynthesized scientific evidence regarding one or a small number of crop diversification man-agement on one or more types of impact.Yet, to date, no study has attempted to provide a comprehensive systematic synthesis of theresults of these meta-analyses. We present here a literature search protocol for the collection,evaluation and description of all meta-analyses on all forms of crop diversification and allperformance criteria.The protocol relies on the use of six bibliographic databases and grey literature sourceswithout any date restriction. Only meta-analyses comparing diversification strategies to lessdiversified systems are considered.The quality of each selected meta-analysis is analyzed. A searchable database containingextracted meta-data, quality criteria and measured effect sizes is built
Bayesian Mixture Models With Focused Clustering for Mixed Ordinal and Nominal Data
Creators: name: DeYoreo, Maria
name: Reiter, Jerome P.
name: Hillygus, D. Sunshine
Publisher: name: arXiv
Year: 2015
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: In some contexts, mixture models can fit certain variables well at the expense of others in ways beyond the analyst's control. For example, when the data include some variables with non-trivial amounts of missing values, the mixture model may fit the marginal distributions of the nearly and fully complete variables at the expense of the variables with high fractions of missing data. Motivated by this setting, we present a mixture model for mixed ordinal and nominal data that splits variables into two groups, focus variables and remainder variables. The model allows the analyst to specify a rich sub-model for the focus variables and a simpler sub-model for remainder variables, yet still capture associations among the variables. Using simulations, we illustrate advantages and limitations of focused clustering compared to mixture models that do not distinguish variables. We apply the model to handle missing values in an analysis of the 2012 American National Election Study, estimating relationships among voting behavior, ideology, and political party affiliation.
description: Supplementary material available from the first author upon request
Further considerations of cosmic ray modulation of infra-red radiation in the atmosphere
Creators: name: Aplin, Karen
name: Lockwood, Mike
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: Understanding effects of ionisation in the lower atmosphere is a new interdisciplinary area, crossing traditionally distinct scientific boundaries. Following the paper of Erlykin et al. (Astropart. Phys. 57--58 (2014) 26--29) we develop the interpretation of observed changes in long-wave (LW) radiation (Aplin and Lockwood, Env. Res. Letts. 8, 015026 (2013)), by taking account of cosmic ray ionisation yields and atmospheric radiative transfer. To demonstrate this, we show that the thermal structure of the whole atmosphere needs to be considered along with the vertical profile of ionisation. Allowing for ionisation by all components of a cosmic ray shower and not just by the muons, reveals that the effect we have detected is certainly not inconsistent with laboratory observations of the LW absorption cross section. The analysis presented here, although very different from that of Erlykin et al., does come to the same conclusion that the events detected were not caused by individual cosmic ray primaries -- not because it is impossible on energetic grounds, but because events of the required energy are too infrequent for the 12/hr rate at which they were seen by the AL experiment. The present paper numerically models the effect of three different scenario changes to the primary GCR spectrum which all reproduce the required magnitude of the observed effect. However, they cannot solely explain the observed delay in the peak effect which, if confirmed, would appear to open up a whole new and interesting area in the study of water oligomers and their effects on LW radiation. We argue that a technical artefact in the earlier experiment is highly unlikely and that our initial observations merit both follow-up experiments and more rigorous, self-consistent, three-dimensional radiative transfer modelling.
description: Accepted for publication in Astroparticle Physics
Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice
Creators: name: McLeod, Howard
name: Szatkiewicz, Jin Peng
name: Crowley, James
name: Adkins, Daniel
name: Wang, Wei
name: de Villena, Fernando Pardo-Manuel
name: Bogue, Molly
name: Kim, Yunjung
name: Yang, Hyuna
name: Quackenbush, Corey
name: Sullivan, Patrick
name: van den Oord, Edwin
name: Threadgill, David
name: Pratt, Amanda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Tardive dyskinesia (TD) is a debilitating, unpredictable and often irreversible side effect resulting from chronic treatment with typical antipsychotic agents such as haloperidol. TD is characterized by repetitive, involuntary, purposeless movements primarily of the orofacial region. In order to investigate genetic susceptibility to TD, we used a validated mouse model for a systems genetics analysis geared toward detecting genetic predictors of TD in human patients. Phenotypic data from 27 inbred strains chronically treated with haloperidol and phenotyped for vacuous chewing movements were subject to a comprehensive genomic analysis involving 426,493 SNPs, 4,047 CNVs, brain gene expression, along with gene network and bioinformatic analysis. Our results identified ~50 genes that we expect to have high prior probabilities for association with haloperidol-induced TD, most of which have never been tested for association with human TD. Among our top candidates were genes regulating the development of brain motor control regions (Zic4, Nkx6-1), glutamate receptors (Grin1, Grin2a), and an indirect target of haloperidol (Drd1a) that has not been as well studied as the direct target, Drd2.