cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ReCAP: ASCO Core Curriculum for Cancer Survivorship Education
Creators: name: Rowland, Julia H
name: Jacobsen, Paul B
name: Henderson, Tara
name: Shapiro, Charles L
name: Rowland, Julia H
name: Mayer, Deborah K
name: Ng, Andrea
name: Surbone, Antonella
name: Henderson, Tara
name: Hurria, Arti
name: Ng, Andrea
name: Shapiro, Charles L
name: Surbone, Antonella
name: Mayer, Deborah K
name: Jacobsen, Paul B
name: Nekhlyudov, Larissa
name: Nekhlyudov, Larissa
name: Hurria, Arti
Publisher: name: American Society of Clinical Oncology (ASCO)
Year: 2016

description: CONTEXT AND QUESTIONS ASKED: The number of cancer survivors is increasing exponentially. Currently there about 15 million cancer survivors, and by 2025, there will be nearly 20 million. Who will provide survivorship care, what are evidenced-based or best care practices, what are best methods to disseminate this information and assess its impact on physician practice, and what are the most cost-effective health care delivery models to serve the majority of survivors?
SUMMARY ANSWER: The ASCO Survivorship Committee in collaboration with the ASCO Professional Development Committee developed a core curriculum and core competencies for physicians, allied health professionals, training programs, and policymaking organizations. Adapted from Institute of Medicine recommendations for survivorship care, the core curriculum and competencies include the following subheadings: surveillance for recurrence and second malignancies, long-term and late effects, health promotion and prevention, psychosocial well-being, special populations including adolescent and young adult survivors, older adult cancer survivors, caregivers of cancer survivors and communication and care coordination.
METHODS: An environmental scan (a process that systematically surveys and interprets relevant data to identify opportunities and barriers) for survivorship was performed. Although survivorship content exists in various courses, conferences, guidelines, and Web-based applications, the information is incomplete and not easily found. Hence, there was a need for this content to be easy to access and available in one place. Content experts formulated the individual sections based on the environmental scan and their knowledge of the various subheadings.
BIAS, CONFOUNDING FACTORS, DRAWBACKS: Both an environmental scan and a comprehensive literature review have standard methodologies. The differences are in scope; an environmental scan is more like an overview, and the standard literature review is more granular. For this article, we felt that environmental scan better served the purpose of developing a survivorship core curriculum and competencies.
REAL-LIFE IMPLICATIONS: Survivorship care is one the most challenging problems oncologists face today and in the near future. Fundamental to the relatively new field of survivorship care is this core curriculum and competencies, which provide the framework necessary to generate appropriate referrals depending on local practices and expertise.
The effect of ethanol upon glucose homeostasis.
Creators: name: Dittmar, Elizabeth A.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1977
Subjects: subject: Biology, Animal Physiology.

description: The effect of an intravenous infusion of ethanol upon the rates of glucose production (Ra) and overall glucose utilization (Rd) was examined in conscious dogs. The animal were studied in the postabsorptive state under basal conditions; during insulin-induced hypoglycaemia; in diabetes induced by pancreatectomy or after a four day fast. The rates of glucose production and utilization were calculated using 3H-labelled glucose as tracer. Changes in blood lactate, plasma glucose and radioimmunoreactive insulin concentrations were followed during the administration of ethanol. The estimated rate of ethanol utilization was determined in the four different states studied. The primed infusion of 0.24--0.29 mM/kg·min ethanol did not change the plasma glucose concentrations nor the rates of glucose production and utilization in normal or diabetic dogs in the postabsorptive state. A significant decrease in Ra prevailed for fifty-five minutes after the beginning of an ethanol infusion at the rate of 0.04 mM/kg·min to dogs fasted for four days. When the same dogs were again fasted for the same duration and administered ethanol at the rate of 0.25 mM/kg min, there was no significant changes in Ra. When insulin was infused at the rate of 4-7 mU/kg min in the presence of ethanol, ethanol had no effect upon the increase in Ra. during insulin-induced hypoglycaemia. During ethanol infusions to fasted of diabetic dogs, blood lactate concentrations increased and insulin levels did not change. In five of the six paired experiments in which hypoglycaemia was induced with insulin with or without ethanol, the plasma insulin concentrations were consistently higher in the presence of ethanol although the metabolic clearance rates of glucose remained unchanged. The estimated rates of ethanol utilization were reduced by fasting but not in diabetes or during insulin-induced hypoglycaemia. In conclusion, ethanol did not interfere with the elevated rate of gluconeogenesis in diabetes nor did it interfere with the hepatic response to hypoglycaemia.
Supplementary document for Dynamic phase manipulation of vertical-cavity surface-emitting lasers via on-chip integration of microfluidic channels - 4935964.pdf
Creators: name: Xie, Yiyang
name: Pan, Guanzhong
name: zhao, zhuangzhuang
name: Wang, Qiuhua
name: Dong, Yibo
name: Hu, Liangchen
name: Sun, Jie
name: Chen, Hongda
name: Xu, Chen
name: Ni, Pei-Nan
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Device characterization
A 160-GHz radar sniffer probe for honey bee detection
Creators: name: Geiger, Martin
name: Hügler, Philipp
name: Galler, Thomas
name: Bandel, Torsten
name: Ott, Peter
name: Rech, Wolf-Henning
name: Walter, Thomas
name: Waldschmidt, Christian
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Chirp-sequence radar
subject: Dielectric waveguide
subject: Flexible radar sensor
subject: Lens antenna
subject: Millimeter wave
subject: MMIC
subject: MMIC-to-waveguide transition
subject: Radar sniffer probe
subject: DDC 620 / Engineering & allied operations
subject: Dielectrics
subject: Lens antennas
subject: Millimeter wave communication systems
subject: Wave guides
subject: Radar
subject: Hohlleiter
subject: Linsenantenne
subject: Millimeterwelle
subject: MMIC

description: The use of radar systems is limited in some applications by spatial constraints or special thermal and environmental conditions. The spatial separation of the sensitive electronics and the more robust antenna by a ﬂexible connection therefore opens up new applications. A 160-GHz radar system with a mechanically ﬂexible front end fulﬁlling these requirements is proposed in this paper. The ﬂexible front end is an extremely low loss dielectric waveguide feeding a dielectric elliptical lens antenna (28 dBi gain). The dielectric waveguide has dielectric losses of 4.5 dB/m at 160 GHz and is very ﬂexible, allowing bending radii of down to 1.5 cm with negligible losses. The dielectric waveguide is fed by a 160-GHz radar monolithic microwave integrated circuit (MMIC), which allows bandwidths of up to 20 GHz for a high range resolution. The transition between MMIC and dielectric waveguide is realized with a rectangular-waveguide interface. The radar back end consists of a phased-locked loop (PLL) with standard components, an intermediate frequency (IF) signal conditioning part, and a Xilinx Zynq 7030 System-On-Module (SOM) with an FPGA and an ARM-based processor. The sampled signal is processed directly on the FPGA with a 2D Fourier transform and is available as a UDP stream with an update rate of up to 15 Hz. In addition, a camera image is taken for each radar measurement. The presented system is used to detect and measure the ﬂight behavior of honey bees. The electronics are housed in a building whereas the ﬂexible dielectric waveguide allows the antenna to be placed anywhere around the beehive, where it is exposed to environmental conditions.
Even business students can reflect: gleaning insights about research
Creators: name: Andrew, Martin
Publisher: name: Swinburne
Year: 2024

description: An under-researched area in New Zealand is the business-focussed academic literacy required by international and migrant students headed for tertiary study, particularly for Bachelor of Business degrees. Such adult learners need a basis of declarative content knowledge of English as an Additional Language (EAL) supported by the practical procedural knowledge acquired during guided report writing. The knowledge they perceive as most useful is gained via targeted research and staged document production. This paper discusses themes emergent from open-coding analysis of 39 Reflective Memoranda written by two streams of English for Business and Computing Studies (EBCS) in 2003/4. These texts chart narratives of the learning process during the writing of guided research reports over 15 weeks. Analysis of the reflections identifies the range of skills learners believe they will use in their academic futures and reveals a perception that procedural knowledge, particularly strategies for facilitating the research and group work processes, is of maximum future value due to its potential to foster ‘how to’ strategies and fashion autonomy. The study is foregrounded by a discussion of effective use of reflection, reflective learning and reflective practice methodology in EAL.
Osteoarthritis-related degeneration alters the biomechanical properties of human menisci before the articular cartilage
Creators: name: Seitz, Andreas Martin
name: Osthaus, Felix
name: Schwer, Jonas
name: Warnecke, Daniela
name: Faschingbauer, Martin
name: Sgroi, Mirco
name: Ignatius, Anita
name: Dürselen, Lutz
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Knee
subject: Degeneration
subject: Instantaneous modulus
subject: Thickness
subject: Water content
subject: Equilibrium modulus
subject: Mapping
subject: DDC 610 / Medicine & health
subject: Knee; Pathology
subject: Meniscus
subject: Kniegelenk
subject: Degeneration

description: An exact understanding of the interplay between the articulating tissues of the knee joint in relation to the osteoarthritis (OA)-related degeneration process is of considerable interest. Therefore, the aim of the present study was to characterize the biomechanical properties of mildly and severely degenerated human knee joints, including their menisci and tibial and femoral articular cartilage (AC) surfaces. A spatial biomechanical mapping of the articulating knee joint surfaces of 12 mildly and 12 severely degenerated human cadaveric knee joints was assessed using a multiaxial mechanical testing machine. To do so, indentation stress relaxation tests were combined with thickness and water content measurements at the lateral and medial menisci and the AC of the tibial plateau and femoral condyles to calculate the instantaneous modulus (IM), relaxation modulus, relaxation percentage, maximum applied force during the indentation, and the water content. With progressing joint degeneration, we found an increase in the lateral and the medial meniscal instantaneous moduli (p < 0.02), relaxation moduli (p < 0.01), and maximum applied forces (p < 0.01), while for the underlying tibial AC, the IM (p = 0.01) and maximum applied force (p < 0.01) decreased only at the medial compartment. Degeneration had no influence on the relaxation percentage of the soft tissues. While the water content of the menisci did not change with progressing degeneration, the severely degenerated tibial AC contained more water (p < 0.04) compared to the mildly degenerated tibial cartilage. The results of this study indicate that degeneration-related (bio-)mechanical changes seem likely to be first detectable in the menisci before the articular knee joint cartilage is affected. Should these findings be further reinforced by structural and imaging analyses, the treatment and diagnostic paradigms of OA might be modified, focusing on the early detection of meniscal degeneration and its respective treatment, with the final aim to delay osteoarthritis onset.
Assessment of trimethylamine-N-oxide at the blood-cerebrospinal fluid barrier: Results from 290 lumbar punctures
Creators: name: Enko, Dietmar
name: Zelzer, Sieglinde
name: Niedrist, Tobias
name: Holasek, Sandra
name: Baranyi, Andreas
name: Schnedl, Wolfgang J.
name: Herrmann, Markus
name: Meinitzer, Andreas
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2020
Subjects: biomarkers
blood-cerebrospinal fluid barrier
liquid chromatography-tandem mass spectrometry
trimethylamine-N-oxide

description: Recently, the microbiome-derived trimethylamine-N-oxide (TMAO) was shown to be present in human cerebrospinal fluid (CSF). However, data on the potential of TMAO crossing the blood-CSF barrier are still lacking. This retrospective study aimed at investigating possible associations between the CSF/serum albumin (QALB) and TMAO (QTMAO) quotient and evaluating QTMAO values in individuals with and without blood-CSF barrier dysfunction. A total of 290 patients, who underwent diagnostic lumbar puncture with QALB and QTMAO determination, were evaluated. Serum and CSF TMAO measurements were performed on a tandem mass spectrometry SCIEX QTRAP 4500 (Applied Biosystems, Framingham, MA, USA) coupled with an Agilent 1260 Infinity HPLC system (Agilent Technologies Santa Clara, CA, USA). Serum and CSF albumin were measured on the Atellica® NEPH 630 system (Siemens Healthineers, Erlangen, Germany). CSF TMAO levels were positively correlated with serum TMAO levels (ρ = 0.709, p < 0.001). The QALB was significantly associated with the QTMAO (ß-coefficient = 0.312; p < 0.001). A total of 117 patients with blood-CSF barrier dysfunction had significantly higher median (Q1 – Q3) QTMAO values (4.7 (2.8 – 7.5) vs. 3.8 (2.5 – 5.7) x 10-1, p = 0.002) compared to 173 individuals with normal blood-CSF barrier function. CSF and serum TMAO concentrations were significantly associated in 290 CSF/serum pairs from lumbar punctures of clinical routine. QALB showed a relevant influence on QTMAO. Present results indicate that TMAO may cross the blood-CSF barrier.
description: EXCLI Journal; 19:Doc1275; ISSN 1611-2156
SHAPE-ID Learning Case Workshops Intermediate Working Paper
Creators: name: Galvini, Giorgia
name: Sessa, Carlo
name: Wallace, Doireann
name: Ohlmeyer, Jane
name: Taylor Wesselink, Keisha
name: Lyall, Catherine
name: Fletcher, Isabel
Publisher: name: Zenodo
Year: 2020
Subjects: subject: interdisciplinarity
subject: transdisciplinarity
subject: workshop
subject: AHSS
subject: Humanities
subject: FOS: Humanities
subject: Arts
subject: Environmental Humanities
subject: Education for Sustainability

description: The SHAPE-ID project was scheduled to organise six learning case workshops across Europe between December 2019 and May 2020 to enable stakeholders to explore best practices in interdisciplinary and transdisciplinary research (IDR/TDR). A report on the workshop series was scheduled for June 2020. The first three of these workshops – held in Dublin in December 2019, Edinburgh in January 2020 and Turin in February 2020 – took place as planned but the remaining three – intended to take place in Bilbao in March, in Warsaw in April and in Zurich in May 2020 – were postponed due to the COVID-19 outbreak. These workshops will now take place in a virtual format in September and October 2020 and the report on the results of all six workshops has been necessarily postponed to the end of November 2020. This working paper has been prepared to share in a preliminary form the results of the first three workshops. We emphasise the provisional nature of this report as the workshop series is ongoing. The outcomes of all six workshops will be synthesised and evaluated when the series is complete.
description: We would like to thank all of the participants of our workshops in Dublin, Edinburgh and Turin, who gave their time so generously to contribute the insights included in this report.
Kuli ngi daw = (La force sacrée du mil) : de la religion du mil à l'Eucharistie chrétienne chez les Gizigas du Nord Cameroun.
Creators: name: Jaouen, René.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Theology.

description: Dix ans après la fin du Concile Vatican II, Paul VI renouvelait la doctrine missionnaire du Décret Ad Gentes et de la Déclaration Nostra Aetate par son Exhortation Apostolique Evangelii Nuntiandi sur l'Evangélisation dans le monde moderne, en date du 8 décembre 1975. Il disait alors que "L'Église évangélise lorsque, par la seule puissance divine du message qu'elle proclame (cf. Rom 1.16: 1 Cor 1, 18;2.4), elle cherche à convertir en même temps la conscience personnelle et collective des hommes, l'activité dans laquelle ils s'engagent, la vie et le milieu concrets qui sont les leurs" (E.N.18). Ce qui est à convertir, c'est donc, non seulement les consciences individuelles, mais aussi ce que le Concile a appelé ailleurs les cultures (G.S. 53). Et Paul VI d'insister sur la profondeur de cette conversion: il s'agit selon lui "d'atteindre et comme de bouleverser par la force de l'Évangile les critères de jugement, les valeurs déterminantes, les points d'intérêt, les lignes de pensée, les sources inspiratrices et les modèles de vie de l'humanidessein du salut" (E.N.19). L'hypothèse de cette recherche, c'est qu'il importe de traduire, non seulement les éléments secondaires, mais la totalité du langage ("matière et forme", symbole, signifiants). Pour atteindre à la profondeur que visait Paul VI, il ne faut pas commencer par faire éclater la structure du langage, en imposant des "limites convenables" (G.S.44) qui seraient des limites à priori étrangères à l'esprit de l'Incarnation. La pratique de l'Eucharistie dans les jeunes Églises d'Afrique fournit un excellent terrain pour vérifier cette hypothèse dans toutes ses dimensions, implications et conséquences. (Abstract shortened by UMI.)
Recommendations for registrants to improve data quality in registration dossiers for chemicals > 1000 tpa
Creators: name: Oertel, Angelika
name: Maul, Katrin
name: Menz, Jakob
Publisher: name: My University
Year: 2018
Subjects: subject: REACH-System
subject: Mutagenität
subject: Genotoxizität
subject: Teratogenität
subject: Abiotischer Abbau
subject: Biologischer Abbau
subject: REACH
subject: mutagenicity
subject: genotoxicity
subject: repeated dose toxicity
subject: toxicity to reproduction
subject: developmental toxicity
subject: abiotic degradation
subject: biotic degradation
subject: Chemicals

description: The standard information requirements necessary for the registration and their adaptation options for high tonnage substances are specified in the ⁠REACH⁠ Regulation (EC) No 1907/2006. Based on the outcome of the REACH Compliance project, it is recommended that registrants scrutinize whether an update of their registration dossier is necessary to meet the information requirements. The presented recommendations are intended to support registrants to improve the quality of their registration dossiers. They address registrants of phase-in substances manufactured or imported in quantities of ≥ 1000 tpa.
title: Enterografía por Resonancia Magnética:preparación, protocolo y principales hallazgos de imagen en pacientes con Enfermedad de Crohn
Creators: name: de Miguel Criado, Jaime
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Pathology
subject: Inflammation
subject: Imaging sequences
subject: Diagnostic procedure
subject: MR
subject: Gastrointestinal tract
subject: Abdomen

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
La enfermedad de Crohn ( EC ) es una enfermedad inflamatoria idiopática del tracto gastrointestinal con un curso impredecible caracterizado por presentar exacerbaciones y remisiones. Para el diagnóstico,
el seguimiento y el correcto tratamiento...
CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles
Creators: name: Man, Kevin
name: Wei, Yunbo
name: Lewin, Sharon R
name: Atnerkar, Anurag
name: Comerford, Iain
name: Deleage, Claire
name: Wang, Peng
name: Yu, Di
name: Zotos, Dimitra
name: Chen, Yaping
name: Xu, Jiawei
name: McColl, Shaun R
name: Chipman, Jeffrey G
name: Sun, Lei
name: Hou, Zhaohua
name: Preston, Simon
name: Minnich, Martina
name: Belz, Gabrielle T
name: Allison, Cody C
name: Ong, Hong Sheng
name: Estes, Jacob D
name: Kallies, Axel
name: Lu, Hao K
name: Landay, Alan L
name: Palendira, Umaimainthan
name: Beilman, Greg J
name: Meckiff, Benjamin J
name: Schacker, Timothy W
name: Fenix, Kevin A
name: Dent, Alexander L
name: Wu, Di
name: Pellegrini, Marc
name: Leong, Yew Ann
name: Long, Heather M
name: Toe, Jesse G
name: Tao, Yong
name: Busslinger, Meinrad
Publisher: name: Springer Nature
Year: 2016

description: B cells and follicular helper T cells in B cell follicles can act as important reservoirs for chronic infection by viruses such as HIV or EBV. Yu and colleagues show that a specialized subpopulation of cytotoxic T cells can enter the B cell follicles to eliminate such virus-infected cells.
An analysis of the capacity for environmental public health surveillance to detect and monitor the health outcomes of a changing climate through an exploratory case study in Nunavut
Creators: name: Champagne-Shields, Isabelle
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Environmental Health.
subject: Health Sciences, Health Care Management.

description: Using a conceptual framework for effective surveillance and through and exploratory case study informed by key informant interviews and document reviews, this thesis explores the capacity for environmental public health surveillance systems in remote Aboriginal communities to detect and monitor the health outcomes related to a changing climate. The findings demonstrate that several activities associated with effective surveillance systems are being performed in Nunavut, including formal and informal data collection approaches to health and environmental information. Nevertheless, this thesis also reveals that the existing health surveillance and environmental monitoring systems are carried out in a manner that involves very little data integration. Recommendations include the investigation of the feasibility of integrating existing data for health-related climate impacts on Nunavummiut and to research and develop the appropriate partnerships between all stakeholders (community, government, academia, others) to better integrate existing health surveillance and environmental monitoring systems.
Aging alters the epigenetic asymmetry of HSC division
Creators: name: Florian, M. Carolina
name: Klose, Markus
name: Sacma, Mehmet
name: Jablanovic, Jelena
name: Knudson, Luke
name: Nattamai, Kalpana J.
name: Marka, Gina
name: Vollmer, Angelika
name: Soller, Karin
name: Sakk, Vadim
name: Cabezas-Wallscheid, Nina
name: Zheng, Yi
name: Mulaw, Medhanie A.
name: Glauche, Ingmar
name: Geiger, Hartmut
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: Cell division analysis
subject: DDC 610 / Medicine & health
subject: Hematopoietic stem cells
subject: Cell cycle
subject: Cell division
subject: Stem cells
subject: Cell polarity
subject: Stem cell transplantation
subject: Chromatin
subject: Cloning, Organism
subject: Blutstammzelle
subject: Periphere Stammzellentransplantation
subject: Zellzyklus
subject: Zellteilung
subject: Chromatin

description: Hematopoietic stem cells (HSCs) balance self-renewal and differentiation to maintain homeostasis. With aging, the frequency of polar HSCs decreases. Cell polarity in HSCs is controlled by the activity of the small RhoGTPase cell division control protein 42 (Cdc42). Here we demonstrate—using a comprehensive set of paired daughter cell analyses that include single-cell 3D confocal imaging, single-cell transplants, single-cell RNA-seq, and single-cell transposase-accessible chromatin sequencing (ATAC-seq)—that the outcome of HSC divisions is strongly linked to the polarity status before mitosis, which is in turn determined by the level of the activity Cdc42 in stem cells. Aged apolar HSCs undergo preferentially self-renewing symmetric divisions, resulting in daughter stem cells with reduced regenerative capacity and lymphoid potential, while young polar HSCs undergo preferentially asymmetric divisions. Mathematical modeling in combination with experimental data implies a mechanistic role of the asymmetric sorting of Cdc42 in determining the potential of daughter cells via epigenetic mechanisms. Therefore, molecules that control HSC polarity might serve as modulators of the mode of stem cell division regulating the potential of daughter cells.
title: REVISIÓN DE LAS TECNICAS QUIRUGICAS EN CIRUGÍA GINECOLóGICA ONCOLOGICA.PAPEL DE LA IMAGEN
Creators: name: Alvarez Moreno, Elena
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen
subject: Genital / Reproductive system female
subject: Oncology
subject: PET-CT
subject: MR
subject: CT
subject: Surgery
subject: Staging
subject: Neoplasia

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisar e ilustrar mediante CT y RM las técnicas quirúrgicas en ginecológica oncológica,
tanto las comunes como las avanzadas,
estableciendo sus indicaciones clínicas,
apariencia postquirúrgica normal,
posibles complicaciones y signos de...
Dynamics of task preparation processes revealed by effect course analysis on response times and error rates
Creators: name: Berger, Alexander
name: Kunde, Wilfried
name: Kiefer, Markus
Publisher: name: Universität Ulm
Year: 2024
Subjects: subject: Human behaviour
subject: Psychology
subject: FOS: Psychology
subject: DDC 150 / Psychology
subject: Work; Psychological aspects
subject: Task analysis
subject: Arbeitsorganisation
subject: Arbeitsverhalten
subject: Konzentrationsfähigkeit

description: Cuing or executing a task impacts processing pathways for task-relevant information. While there is ample evidence that processing associated with task execution changes with practice, such evidence regarding cue-induced task preparation is scarce. Here we explored practice-related changes of processing pathways by task cuing in order to assess the plasticity of task preparation. We first developed and validated a new method for the study of practice-related changes, the effect course analysis. The effect course analysis is a model-free, non-parametric method designed to reveal effect changes within an experimental session on a continuous time scale. Then we applied this method to a new study in which cued task sets were supposed to remain activated during assessment of task-relevant pathways, as potential task execution was postponed at the end of the trial. The results showed that, with little practice, task cuing amplified task-relevant pathways, whereas this effect vanished with practice, suggesting that practice prompts fundamental changes of how task cues are used for task preparation. Hence, if one cannot be certain that cognitive processing is stationary, investigating the time course of experimental effects appears to be crucial to determine how cognitive processing is influenced by practice.
Supplementary document for Patchwork Metasurface Quantum Well Infrared Photodetectors with Broadened Photoresponse - 4936249.pdf
Creators: name: Hainey, Mel
name: Mano, Takaaki
name: Kasaya, Takeshi
name: Jimba, Yoji
name: Miyazaki, H.
name: Ochiai, Tetsuyuki
name: Osato, Hirotaka
name: Watanabe, Kazuhiro
name: Sugimoto, Yoshimasa
name: Kawazu, Takuya
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Updated Supplemental information
An information theory interpretation of relativistic phenomena
Creators: name: Boardman, Gareth
Publisher: name: Swinburne
Year: 2024

description: It is well recognized that two of the foundational theories of modern physics, relativity and quantum mechanics, are inconsistent. Efforts to overcome this through intensive pursuit of unifying theoretical frameworks or improvements in experimental precision as pursued by Robertson-Mansouri-Sexl and Standard-Model-Extension test theory protocols, have so far proven unsuccessful. Nonetheless, empirical evidence deriving from investigations inspired by the twentieth-century 'EPR' polemic, can now claim to have identified 'locality' and 'separability' as notions integral to special relativity theory inconsistent with quantum mechanics and experimental evidence supporting it. Following intimations of J.S. Bell, L. Smolin, Maudlin and others, the history and philosophy of science are engaged as research tools to uncover the origins of the assumptions underlying such incompatibility. In particular, known but prevalent fallacies and the deprecation of processes as described by Whitehead, together with recent insights into the functional distinctions between representative models and explanatory theories, are engaged. Analysis of the evolution of optical and electromagnetic theorizing is then suggested to demonstrate that the choice of a mechanically compatible model of electromagnetic radiation, as has conventionally underwritten development of the light-speed postulate of special relativity, is inappropriate. Pursuing options made available within a multiple models idealization of optical and electromagnetic phenomena, replacement of the sponsoring model by a nonlocal and non-separable wavefront process of radiation of the form advanced by Fresnel and Kirchhoff on the basis of Huygens' principle, suggests the possibility of reformulation of relativity theory without incurring such conflicts. However, choice of a wavefront electrodynamic model including the extinction theorem of Ewald and Oseen, equally suggests possible theory reformulation without necessitating a four-dimensional construct of space and time or postulating an absolute constancy of light-speed in vacuum. Such a constancy can in turn be considered as demonstrating an innate limitation on empirical observation resulting from the loss of relative velocity information during electromagnetic transmission due to the memorylessness of the Markov propagation process of refraction together with information flow discontinuity resulting from dielectric boundary extinction events. Such characteristics are shown to be applicable to electromagnetic radiation of all frequencies. Further, from a wavefront reformulated hypothesis of inertial relative motion, it appears possible to demonstrate that the Galilean principle of relativity can be preserved. However, Lorentz invariance would then require reinterpretation wherein the Lorentz transform group would be deemed to quantify the degree of information distortion inherently experienced by any empirical enquiry into electrodynamics involving relative motion.
title: Examining the Concept of Participation in Traditional Societies: A Case of the Akan Traditional Society of Ghana
Creators: name: Oduro-Sarpong, Samuel
Publisher: name: University of Massachusetts Amherst
Year: 2003
Subjects: subject: Education

description: There is the general impression that traditional societies, especially those in the developing world, lack participatory mechanisms for their citizens to effectively participate in decisions affecting their lives. This study therefore is an attempt to examine the concept of participation in relation to decision-making and execution of community self-help projects in the Akan traditional society in Ghana. The objective is not to confirm or disagree with this general notion, but to reveal the processes and levels of involvement of the Akans in decisions affecting their lives. For better understanding of the decision-making processes in the Akan society, one needs to examine the various cultural events depicting the life-cycle of the Akans. The study therefore used the Rites of Passage of the Akan - Birth/Naming, Initiation, Marriage and Death/Funeral - as case studies. In addition to these cultural events, some self-help projects executed by the Akans in some communities were also examined. Since the Akan society is undergoing significant transformation especially due to modernization and western influence, some activities and participation processes of few external community development agencies working in the Akanland were also examined for comparison. The study reviewed some literature on Culture and Participation and focused on Hofstedes's (2002) four main dimensions of culture for the theoretical framework. The study concluded that the Akan society is collectivist, has large power distance, has high uncertainty avoidance and is masculine. The values of these dimensions significantly affect one's involvement in decision-making. Therefore there are various levels of participation in decision-making in the Akan Society mainly based on age, sex, group membership and position in the family or the community. Again the study reaffirmed that the Akan culture has rich indigenous knowledge based on their cultural values that development partners working in the Akanland could utilize for successful execution of programs.
Distinct effects of IL-6 classic and trans-signaling in bone fracture healing
Creators: name: Prystaz, Katja
name: Kaiser, Kathrin
name: Kovtun, Anna
name: Haffner-Luntzer, Melanie
name: Fischer, Verena
name: Rapp, Anna E.
name: Liedert, Astrid
name: Strauss, Gudrun
name: Wätzig, Georg H.
name: Rose-John, Stefan
name: Ignatius, Anita
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: Bone healing
subject: Repair phase
subject: DDC 610 / Medicine & health
subject: Bone and bones
subject: Fracture healing
subject: Inflammation
subject: Bone regeneration
subject: Interleukin-6
subject: Frakturheilung
subject: Entzündung
subject: Knochenregeneration
subject: Interleukin 6

description: Bone healing is a complex process with closely linked phases of inflammation, regeneration, and remodeling. IL-6 may crucially regulate this process; however, the underlying mechanisms are unclear. IL-6 signals are transmitted via the transmembrane glycoprotein 130 by two distinct mechanisms: classic signaling using the membrane-anchored IL-6 receptor and trans-signaling using its soluble form. Herein, we investigated the hypothesis that IL-6 classic and trans-signaling have different functions during bone healing. To investigate fracture healing, 12-week-old C57BL/6J mice underwent a femur osteotomy. To study the function of IL-6 during the inflammatory phase, either an anti–IL-6 antibody, which inhibits IL-6 classic and trans-signaling, or soluble glycoprotein 130 fusion protein, which selectively blocks trans-signaling, was injected after 30 minutes and 48 hours. To analyze IL-6 effects in the repair phase, compounds were injected from day 7 onwards. Global IL-6 inhibition in the early phase after fracture reduced systemic inflammation, the recruitment of immune cells, and bone regeneration, resulting in delayed fracture healing. Global IL-6 inhibition during the repair phase disturbed bone formation and remodeling. In contrast, inhibition of IL-6 trans-signaling exerted minor effects on the immune response and did not influence bone repair, suggesting that the classic pathway accounts for most of the effects observed after global IL-6 inhibition. Our results reveal that IL-6 classic signaling, but not IL-6 trans-signaling, is essential for bone repair.
Deletion of Cdk5 in macrophages ameliorates anti-inflammatory response during endotoxemia through induction of C-Maf and Il-10
Creators: name: Pfänder, Pauline
name: Eiers, Ann-Kathrin
name: Burret, Ute
name: Vettorazzi, Sabine
name: Shenhar-Tsarfaty, Shani
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Cdk5
subject: c-Maf
subject: Il-10
subject: anti-inflammation
subject: DDC 570 / Life sciences
subject: Macrophages
subject: Cyclin-dependent kinases
subject: Interleukin-10
subject: Cyclin-Dependent Kinase 5
subject: Makrophage
subject: Cyclin-abhängige Kinasen

description: Immune response control is critical as excessive cytokine production can be detrimental and damage the host. Interleukin-10 (Il-10), an anti-inflammatory cytokine produced primarily by macrophages, is a key regulator that counteracts and controls excessive inflammatory response. Il-10 expression is regulated through the transcription factor c-Maf. Another regulator of Il-10 production is p35, an activator of the cyclin-dependent kinase 5 (Cdk5), which decreases Il-10 production in macrophages, thus increasing inflammation. However, Cdk5 regulation of c-Maf and the involvement of Il-10 production in macrophages has not yet been investigated. We used in vitro primary bone marrow-derived macrophages (BMDMs) lacking Cdk5, stimulated them with lipopolysaccharid (LPS) and observed increased levels of c-Maf and Il-10. In an in vivo mouse model of LPS-induced endotoxemia, mice lacking Cdk5 in macrophages showed increased levels of c-Maf and elevated levels of Il-10 in lungs as well as in plasma, resulting in ameliorated survival. Taken together, we identified Cdk5 as a potential novel regulator of Il-10 production through c-Maf in macrophages under inflammatory conditions. Our results suggest that inhibition of Cdk5 enhances the c-Maf-Il-10 axis and thus potentiates improvement of anti-inflammatory therapy.
La démocratie agonique au Canada Une étude des idées de trois penseurs dans l'action
Creators: name: Brady, Marie-Joie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Political Science, General.

description: Cette thèse porte sur l'étude de la pensée de Gil Rémillard, Mary Ellen Turpel et André Burelle, trois penseurs dans l'action impliqués dans les débats constitutionnels autour des accords de Meech et de Charlottetown. Il s'agit d'étudier leurs travaux à partir du cadre de la démocratie agonique, un cadre forme d'une triade conceptuelle: le conflit, l'amitié et l'hospitalité. Cette triade conceptuelle s'inspire principalement des travaux de Chantal Mouffe, William Connolly et Jacques Derrida. Après un premier chapitre portant sur un exposé théorique sur le thème de l'agonisme, le deuxième chapitre offre une revue évènementielle et de la littérature sur la politique canadienne en général et en particulier sur les débats constitutionnels et identitaires canadiens. L'auteure présente en troisième chapitre une étude approfondie des filiations philosophiques de Turpel, Burelle et Rémillard à la lumière du cadre agonique proposé. En quatrième chapitre, il s'agit d'étudier la façon dont chacun conceptualisé les raisons d'être, les fondements historiques du Canada et ici encore, de voir comment leurs perspectives bénéficient d'une lecture agonique et comment elles contribuent à une compréhension agonique du Canada. Au dernier chapitre, le rôle de penseurs dans l'action des trois sujets étudiés apparaît encore plus clairement, car l'auteure y étudie leurs propositions d'avenir pour le Canada. La conclusion permet de regrouper les éléments de réponse à la question de recherche principale, à savoir "La pensée constitutionnelle de Gil Rémillard, André Burelle et Mary Ellen Turpel contribue-t-elle au développement de rapports politiques agoniques au Canada et si oui, de quelle façon?". De plus, cette conclusion mené à réfléchir plus à fond sur la pertinence d'un cadre agonique pour penser le Canada et sur les effets de l'échec de la pensée de ces trois penseurs dans l'action pour l'avenir du pays.
title: Valoración de la inestabilidad rotuliana por TC. Medidas, aplicaciones y casos prácticos.
Creators: name: Lopez Marin, Rafael Pblo
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Musculoskeletal bone
subject: CT
subject: Diagnostic procedure
subject: Image compression

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Resumen de las medidas radiológicas más útilizadas en la valoración de la inestabilidad femoropatelar y su valor diagnóstico por TC. Propuesta de protocolo de realización e informe de la prueba diagnóstica,
con unos ejemplos prácticos...
Area-based socioeconomic disparities in mortality due to unintentional injury and youth suicide in British Columbia, 2009–2013
Creators: name: Zandy, Moe
name: Zhang, Li Rita
name: Kao, Diana
name: Rajabali, Fahra
name: Turcotte, Kate
name: Zheng, Alex
name: Oakey, Megan
name: Smolina, Kate
name: Pike, Ian, 1958-
name: Rasali, Drona
Publisher: name: Public Health Agency of Canada
Year: 2021

description: Introduction: The association between health outcomes and socioeconomic status (SES) has been widely documented, and mortality due to unintentional injuries continues to rank among the leading causes of death among British Columbians. This paper quantified the SES-related disparities in the mortality burden of three British Columbia’s provincial injury prevention priority areas: falls among seniors, transport injury, and youth suicide. Methods: Mortality data (2009 to 2013) from Vital Statistics and dissemination area or local health area level socioeconomic data from CensusPlus 2011 were linked to examine five-year age-standardized mortality rates (ASMRs) and disparities in ASMRs of unintentional injuries and subtypes including falls among seniors (aged 65+) and transport-related injuries as well as the intentional injury type of youth suicide (aged 15 to 24). Disparities by sex and geography were examined, and relative and absolute disparities were calculated between the least and most privileged areas based on income, education, employment, material deprivation, and social deprivation quintiles. Results: Our study highlighted significant sex differences in the mortality burden of falls among seniors, transport injury, and youth suicide with males experiencing significantly higher mortality rates. Notable geographic variations in overall unintentional injury ASMR were also observed across the province. In general, people living in areas with lower income and higher levels of material deprivation had increasingly higher mortality rates compared to their counterparts living in more privileged areas. Conclusion: The significant differences in unintentional and intentional injury-related mortality outcomes between the sexes and by SES present opportunities for targeted prevention strategies that address the disparities.
title: Aportación del estudio Doppler TSA  en el estudio de la relación entre Fragilidad y aterosclerosis subclínica en ancianos
Creators: name: CASADO MORAGON Luis Martín, Luiis Martin
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Arteriosclerosis
subject: Diagnostic procedure
subject: Ultrasound-Colour Doppler
subject: Geriatrics

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Analizar la relación entre fragilidad según criterios Fried modificados y aterosclerosis subclínica,
en ancianos independientes en ABVD,valorando la contribución del estudio ecodoppler...
title: Angioresonancia Renal sin contraste en el estudio de la Hipertensión Renovascular.
Creators: name: López García, Jorge Argimiro
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Obstruction / Occlusion
subject: Arteriosclerosis
subject: Aneurysms
subject: Diagnostic procedure
subject: Technology assessment
subject: Comparative studies
subject: MR-Angiography
subject: Catheter arteriography
subject: Vascular
subject: Abdomen

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Evaluar la Angioresonancia renal sin contraste en la detección de las estenosis de las arterias...
Supplementary document for Patchwork Metasurface Quantum Well Infrared Photodetectors with Broadened Photoresponse - 4936249.pdf
Creators: name: Hainey, Mel
name: Mano, Takaaki
name: Kasaya, Takeshi
name: Jimba, Yoji
name: Miyazaki, H.
name: Ochiai, Tetsuyuki
name: Osato, Hirotaka
name: Watanabe, Kazuhiro
name: Sugimoto, Yoshimasa
name: Kawazu, Takuya
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Updated Supplemental information
Taboo to mainstream: an industrial design solution to sex toy production
Creators: name: Glover, Judith
Publisher: name: Swinburne
Year: 2024

description: Sex toys are rarely a topic for academic consideration let alone a PHD. They generally remain hidden and anonymous products poorly conceived and designed made of unsafe materials produced by the pornography industry with outdated views on female sexuality and gender. Yet sexuality and sexual practice is central to human wellbeing. This thesis challenges the notions of such products as taboo and unworthy of consideration by the design disciplines. This thesis addresses both the technical considerations and socio-sexual behaviour and belief systems that prevent this product genre being considered mainstream product design and provides an exemplar of how design culture, process and methods can align the industry with contemporary female consumers.
title: Emergecias tubo-ováricas en adolescentes: Lo que el radiologo debe saber
Creators: name: del Riego Ferrari, Javier
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Paediatric
subject: Ultrasound
subject: Ultrasound-Colour Doppler
subject: Education
subject: Image compression
subject: Diagnostic procedure
subject: Oedema
subject: Cysts
subject: Ischaemia / Infarction

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
El propósito de esta presentación es describir e ilustrar las emergencias tubo-ováricas de origen no infeccioso,
causa poco frecuente de abdomen agudo en adolescentes,
que pueden dar lugar a una significante morbilidad.
Son patologías que se...
Delaney Young SARC 2024
Creators: name: Young, Delaney
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: The anterior cruciate ligament (ACL) plays a crucial role in function of the knee, from day-to-day mobility to performance of athletes. After ACL tear and surgical reconstruction, many suffer from a multitude of complications involving the function and physical composition of the knee. Two major changes seen after ALCR include decreased quadriceps strength and changes in the composition of the articular cartilage. This summer, I aimed to investigate the associations between quadriceps function and cartilage composition in the knee after anterior cruciate ligament reconstruction (ACL-R) surgery