cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Three-dimensional Coherent Structures of Electrokinetic Instability
Creators: name: Demekhin, E. A.
name: Nikitin, N. V.
name: Shelistov, V. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: A direct numerical simulation of the three-dimensional elektrokinetic instability near a charge selective surface (electric membrane, electrode, or system of micro-/nanochannels) is carried out and analyzed. A special finite-difference method was used for the space discretization along with a semi-implicit $3\frac{1}{3}$-step Runge-Kutta scheme for the integration in time. The calculations employed parallel computing. Three characteristic patterns, which correspond to the overlimiting currents, are observed: (a) two-dimensional electroconvective rolls, (b) three-dimensional regular hexagonal structures, and (c) three-dimensional structures of spatiotemporal chaos, which are a combination of unsteady hexagons, quadrangles and triangles. The transition from (b) to (c) is accompanied by the generation of interacting two-dimensional solitary pulses.
Sonnenfleckenzeichnung Nr. 126.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.05.1995, 07:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Lectures on mathematical aspects of (twisted) supersymmetric gauge theories
Creators: name: Costello, Kevin
name: Scheimbauer, Claudia
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics

description: Supersymmetric gauge theories have played a central role in applications of quantum field theory to mathematics. Topologically twisted supersymmetric gauge theories often admit a rigorous mathematical description: for example, the Donaldson invariants of a 4-manifold can be interpreted as the correlation functions of a topologically twisted N=2 gauge theory. The aim of these lectures is to describe a mathematical formulation of partially-twisted supersymmetric gauge theories (in perturbation theory). These partially twisted theories are intermediate in complexity between the physical theory and the topologically twisted theories. Moreover, we will sketch how the operators of such a theory form a two complex dimensional analog of a vertex algebra. Finally, we will consider a deformation of the N=1 theory and discuss its relation to the Yangian, as explained in arXiv:1308.0370 and arXiv:1303.2632.
description: Notes from a lecture series by the first author at the Les Houches Winter School on Mathematical Physics in 2012. To appear in the proceedings of this conference. Related to papers arXiv:1308.0370, arXiv:1303.2632, and arXiv:1111.4234
Sonnenfleckenzeichnung Nr. 7.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.01.1995, 09:00, erstellt von Michele Bianda
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 1.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 147.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.06.1995, 07:30, erstellt von Michele Bianda
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 241.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.10.1995, 08:45, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
A multiwavelength study of embedded clusters in W5-east, NGC7538, S235, S252 and S254-S258
Creators: name: Chavarria, L.
name: Allen, L.
name: Brunt, C.
name: Hora, J. L.
name: Muench, A.
name: Fazio, G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present Spitzer, NIR and millimeter observations of the massive star forming regions W5-east, S235, S252, S254-S258 and NGC7538. Spitzer data is combined with near-IR observations to identify and classify the young population while 12CO and 13CO observations are used to examine the parental molecular cloud. We detect in total 3021 young stellar objects (YSOs). Of those, 539 are classified as Class I, and 1186 as Class II sources. YSOs are distributed in groups surrounded by a more scattered population. Class I sources are more hierarchically organized than Class II and associated with the most dense molecular material. We identify in total 41 embedded clusters containing between 52 and 73% of the YSOs. Clusters are in general non-virialized, turbulent and have star formation efficiencies between 5 and 50%. We compare the physical properties of embedded clusters harboring massive stars (MEC) and low-mass embedded clusters (LEC) and find that both groups follow similar correlations where the MEC are an extrapolation of the LEC. The mean separation between MEC members is smaller compared to the cluster Jeans length than for LEC members. These results are in agreement with a scenario where stars are formed in hierarchically distributed dusty filaments where fragmentation is mainly driven by turbulence for the more massive clusters. We find several young OB-type stars having IR-excess emission which may be due to the presence of an accretion disk.
description: Accepted for publication in MNRAS
Modeling delay in genetic networks: From delay birth-death processes to delay stochastic differential equations
Creators: name: Gupta, Chinmaya
name: López, José Manuel
name: Azencott, Robert
name: Bennett, Matthew R
name: Josić, Krešimir
name: Ott, William
Publisher: name: arXiv
Year: 2014
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Mathematical Physics (math-ph)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Biological sciences
subject: FOS: Physical sciences
subject: 60G07, 60K10, 92B05, 92C40

description: Delay is an important and ubiquitous aspect of many biochemical processes. For example, delay plays a central role in the dynamics of genetic regulatory networks as it stems from the sequential assembly of first mRNA and then protein. Genetic regulatory networks are therefore frequently modeled as stochastic birth-death processes with delay. Here we examine the relationship between delay birth-death processes and their appropriate approximating delay chemical Langevin equations. We prove that the distance between these two descriptions, as measured by expectations of functionals of the processes, converges to zero with increasing system size. Further, we prove that the delay birth-death process converges to the thermodynamic limit as system size tends to infinity. Our results hold for both fixed delay and distributed delay. Simulations demonstrate that the delay chemical Langevin approximation is accurate even at moderate system sizes. It captures dynamical features such as the spatial and temporal distributions of transition pathways in metastable systems, oscillatory behavior in negative feedback circuits, and cross-correlations between nodes in a network. Overall, these results provide a foundation for using delay stochastic differential equations to approximate the dynamics of birth-death processes with delay.
Sonnenfleckenzeichnung Nr. 250.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.10.1995, 08:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
X-ray binary formation in low-metallicity blue compact dwarf galaxies
Creators: name: Brorby, Matthew
name: Kaaret, Philip
name: Prestwich, Andrea
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: X-rays from binaries in small, metal-deficient galaxies may have contributed significantly to the heating and reionization of the early universe. We investigate this claim by studying blue compact dwarfs (BCDs) as local analogues to these early galaxies. We constrain the relation of the X-ray luminosity function (XLF) to the star-formation rate (SFR) using a Bayesian approach applied to a sample of 25 BCDs. The functional form of the XLF is fixed to that found for near-solar metallicity galaxies and is used to find the probability distribution of the normalisation that relates X-ray luminosity to SFR. Our results suggest that the XLF normalisation for low metallicity BCDs (12+log(O/H) < 7.7) is not consistent with the XLF normalisation for galaxies with near solar metallicities, at a confidence level of 1-5E-6. The XLF normalisation for the BCDs is found to be 14.5 +/- 4.8 (M_solar^-1 yr), a factor of 9.7 +/- 3.2 higher than for near solar metallicity galaxies. Simultaneous determination of the XLF normalisation and power law index result in estimates of q = 21.2^+12.2_-8.8) (M_solar^-1 yr) and alpha = 1.89^{+0.41}_{-0.30}, respectively. Our results suggest a significant enhancement in the population of high-mass X-ray binaries in BCDs compared to the near-solar metallicity galaxies. This suggests that X-ray binaries could have been a significant source of heating in the early universe.
description: 8 pages, 4 figures, To appear in MNRAS
A Bayesian linear model for the high-dimensional inverse problem of seismic tomography
Creators: name: Zhang, Ran
name: Czado, Claudia
name: Sigloch, Karin
Publisher: name: arXiv
Year: 2013
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: We apply a linear Bayesian model to seismic tomography, a high-dimensional inverse problem in geophysics. The objective is to estimate the three-dimensional structure of the earth's interior from data measured at its surface. Since this typically involves estimating thousands of unknowns or more, it has always been treated as a linear(ized) optimization problem. Here we present a Bayesian hierarchical model to estimate the joint distribution of earth structural and earthquake source parameters. An ellipsoidal spatial prior allows to accommodate the layered nature of the earth's mantle. With our efficient algorithm we can sample the posterior distributions for large-scale linear inverse problems and provide precise uncertainty quantification in terms of parameter distributions and credible intervals given the data. We apply the method to a full-fledged tomography problem, an inversion for upper-mantle structure under western North America that involves more than 11,000 parameters. In studies on simulated and real data, we show that our approach retrieves the major structures of the earth's interior as well as classical least-squares minimization, while additionally providing uncertainty assessments.
description: Published in at http://dx.doi.org/10.1214/12-AOAS623 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Sonnenfleckenzeichnung Nr. 246.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.10.1995, 08:15, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 82.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.04.1995, 07:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
NO MUNDO DOS DADOS
Creators: name: Escola De Dados
Publisher: name: Zenodo
Year: 2020
Subjects: Covid 19
Pandemia
Números Oficiais
Escola de Dados
Coronavírus
Ministério da Saúde
ONU
Visualização de Dados
Calebe

description: Com a pandemia do novo coronavírus, visualização de dados tornou-se uma questão de sobrevivência. Curvas mostrando a disseminação da doença se popularizaram e o movimento para “achatar a curva” (#FlattenTheCurve) ganharam as redes sociais na mobilização em prol das medidas de contenção do vírus. A publicação feita no site da Escola de Dados mostra a preocupação que deveria existir em passar informações importantes utilizando os dados, porém faz uma reflexão sobre a ausência dos dados disponibilizados para a sociedade ou seja os números oficiais durante a pandemia.
description: A informação completa está no site Escola de Dados. https://escoladedados.org/2020/04/boletim-de-dados-covid-19-recursos-e-dicas/
description: {"references": ["CALEBEUM", "ESCOLA DE DADOS"]}
Approximate symmetries of the Harry Dym equation
Creators: name: Nadjafikhah, Mehdi
name: Kabi-Nejad, Parastoo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In this paper, we derive the first order approximate symmetries for the Harry Dym equation by the method of approximate transformation groups proposed by Baikov, Gaszizov and Ibragimov. Moreover, we investigate the structure of the Lie algebra of symmetries of the perturbed Harry Dym equation. We compute the one-dimensional optimal system of subalgebras as well as point out some approximately differential invariants with respect to the generators of Lie algebra and optimal system.
description: 11 pages
Sonnenfleckenzeichnung Nr. 214.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.08.1995, 09:45, erstellt von Michele Bianda
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Coral Communities From Gaspar Strait, Bangka Belitung, Indonesia
Creators: name: Singgih Afifa Putra
name: Syari, Indra Ambalika
name: Akbar, Helmy
name: Suyatna, Iwan
name: Setiamarga, Davin H. E.
Publisher: name: F1000 Research Limited
Year: 2018

description: The aim of the study was to describe the coral reef condition in Bangka Belitung Islands, particularly from Gaspar Strait. Nine islands inside the strait were visited (i.e. Langer, Kembung, Piling, Aur, Salma, Pongok, Celagen, Kelapan, and Lepar Island), and a line transect was used to observed coral reef conditions. Coral cover was found to be predominantly in fair conditions (25-50%). Degradation of the coral community in Bangka Belitung Islands is likely caused by human activities.
Sonnenfleckenzeichnung Nr. 144.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.06.1995, 07:15, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
RECOMENDAÇÕES PARA TRANSPARÊNCIA DE CONTRATAÇÕES EMERGENCIAIS EM RESPOSTA À COVID-19
Creators: name: TCU
name: Transparência Internacional-Brasil
Publisher: name: Zenodo
Year: 2020
Subjects: Dados Abertos Governamentais
Covid-19
Pandemia
Contratações
Transparência
Brasil
Corrupção
TCU
Calebe

description: Texto Calebe: Base para verificar arquivos de dados abertos governamentais com informações sobre contratações emergenciais durante a pandemia. Texto retirado do Portal do Tribunal de Contas da União (TCU) O Tribunal de Contas da União (TCU) e a organização não-governamental Transparência Internacional-Brasil lançaram o guia Recomendações para Transparência de Contratações Emergenciais em Resposta à Covid-19. A ideia é que a cartilha sirva de referência para a prevenção e o combate a corrupção no atual cenário, oferecendo a gestores e órgãos de controle informações práticas para que a União, os Estados e os Municípios possam conduzir de maneira adequada a administração dos recursos públicos durante a crise. Referencial - As recomendações foram pensadas a partir da legislação brasileira (Lei de Licitações, Lei de Acesso à Informação (LAI), Política Nacional de Dados Abertos) e das melhores práticas sugeridas e desenvolvidas por entidades internacionais e organizações da sociedade civil com histórico de atuação na promoção da integridade e transparência. Serviu ainda de referência o estudo "Contratações Públicas em Situações de Emergência", desenvolvido pela Transparência Internacional – Brasil em conjunto com 12 escritórios da entidade na América Latina. Por Secom/TCU, com informações da Transparência Internacional – Brasil https://portal.tcu.gov.br/ https://comunidade.transparenciainternacional.org.br/asset/86:tibr-recomendacoes-de-contratacoes-emergenciais-covid19?stream=1
description: https://portal.tcu.gov.br/gestao-de-conteudos-no-portal/sobre-o-portal/termos-de-uso.htm
Case report: congenital myasthenia syndrome in a newborn with antibodies against acetylcholyne receptor
Creators: name: Muñoz, Sergio García
name: Fernández, Alfredo Pérez-Alija
name: Jiménez, Inmaculada Puerta
name: Torres, Rafael Jiménez
Publisher: name: F1000 Research Limited
Year: 2018

description: Here we describe a case of a newborn presenting with bilateral palpebral ptosis and elevated acetylcholyne receptor antibodies, presumptively diagnosed as a congenital myasthenia syndrome.
Bioinformatics design of MiniPromoters for targeted delivery of expression
Creators: name: Fornes, Oriol
name: Farkas, Rachelle A.
name: Korecki, Andrea J.
name: Siu Ling Lam
name: Hickmott, Jack W.
name: Arenillas, David J.
name: Mathelier, Anthony
name: Simpson, Elizabeth M.
name: Wyeth W. Wasserman
Publisher: name: F1000 Research Limited
Year: 2018

description: Gene therapy has re-emerged as a viable treatment for rare genetic disorders. Key to recent progress in the field is non-insertional gene delivery using adeno-associated virus (AAV) vectors. Limited by the restricted payload capacity of AAV vectors, most AAV-based gene therapies use small, ubiquitous promoters. As a result, off-target expression of the therapeutic gene can occur, which may in turn have undesired side effects. In this context, designing selective promoters that restrict the expression of the therapeutic genes to the clinically relevant cells is an important research goal.

In the past, we have shown the capacity to design compact, selective promoter sequences (i.e. MiniPromoters) for targeting specific cells within the brain and eye. The design of a MiniPromoter was a manual process involving three steps: 1) literature search for a gene with restricted expression patterns in the target cells; 2) identification of the cis-regulatory regions (CRRs) of that gene (i.e. promoter and enhancers); and 3) assembly of a subset of the gene’s CRRs into a MiniPromoter sequence.

We are developing the OnTarget software to automate the design of MiniPromoters. It has three main components: 1) a Data Repository linking thousands of public processed experiments (CAGE, GRO-seq, ATAC-seq, DNase-seq, ChIP-seq, Hi-C, etc.) from multiple human primary cells, tissues and cell lines with in-house data collections (JASPAR, MANTA, allele-specific binding events, etc.); 2) a Selection Module for identifying and selecting CRRs of human genes in cell/tissue-specific contexts; and 3) a Design Module for fine-tuning the identified CRRs and modifying transcription factor binding sites within these CRRs in order to modulate the amount of delivered expression.

We have applied the OnTarget software to design different MiniPromoters driving cell type-specific expression patterns, including ganglion cells (based on CRRs of the NEFL and NEFM genes), bipolar cells (based on PCP2), or neurons from the locus coeruleus (based on DBH). We anticipate that OnTarget will simplify and improve the design of promoters for targeted delivery of gene therapies while limiting off-target side effects for patients.
Sonnenfleckenzeichnung Nr. 47.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.02.1995, 15:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Optical effects related to Keplerian discs orbiting Kehagias-Sfetsos naked singularities
Creators: name: Stuchlik, Zdenek
name: Schee, Jan
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We demonstrate possible optical signatures of the Kehagias-Sfetsos naked singularity spacetimes representing spherically symmetric vacuum solution of the modified Hořava gravity. In such spacetimes, accretion structures significantly different from those present in the standard black hole spacetimes occur due to the "antigravity" effect causing existence of an internal static sphere surrounded by Keplerian discs. We focus our attention on the optical effects related to the Keplerian accretion discs, constructing the optical appearance of the Keplerian discs, the spectral continuum due to their thermal radiation, and spectral profiled lines generated in the innermost parts of such discs. The KS naked singularity signature is strongly encoded in the characteristics of predicted optical effects, especially in the case of the spectral continuum and spectral lines profiled by the strong gravity of the spacetimes, due to the region of the vanishing of the angular velocity gradient influencing the effectivity of the viscosity mechanism. We can conclude that optical signatures of the Kehagias-Sfetsos naked singularities can be well distinguished from the signatures of the standard black holes.
MPEC 2023-U293 : 2023 UL10
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 UL10

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Sonnenfleckenzeichnung Nr. 239.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.10.1995, 08:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Thinking outside the box: fluctuations and finite size effects
Creators: name: Villamaina, Dario
name: Trizac, Emmanuel
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The isothermal compressibility of an interacting or non interacting system may be extracted from the fluctuations of the number of particles in a well chosen control volume. Finite size effects are prevalent and should then be accounted for to obtain a meaningful, thermodynamic compressibility. In the traditional computational setup where a given simulation box is replicated with periodic boundary conditions, we study particle number fluctuations outside the box (i.e. when the control volume exceeds the box itself), which bear relevant thermodynamic information. We also investigate the related problem of extracting the compressibility from the structure factor in the small wave-vector limit ($k\to 0$). The calculation should be restricted to the discrete set of wave-vectors $k$ that are compatible with the periodicity of the system, and we assess the consequences of considering other $k$ values, a widespread error among beginners.
description: 17 pages, 9 figures
Sonnenfleckenzeichnung Nr. 228.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 18.09.1995, 13:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 188.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 04.08.1995, 08:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 182.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.07.1995, 07:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Nonlinear (Anharmonic) Casimir Oscillator
Creators: name: Razmi, Habibollah
name: Mohammadi, Mohammad Reza
name: Abdollahi, Mahnaz
name: Fazeli, Seyed Mahdi
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We want to study the dynamics of a simple linear harmonic micro spring which is under the influence of the quantum Casimir force/pressure and thus behaves as a (an) nonlinear (anharmonic) Casimir oscillator. Generally,the equation of motion of this nonlinear micromechanical Casimir oscillator has no exact solvable (analytical)solution and the turning point(s) of the system has (have) no fixed position(s); however, for particular values of the stiffness of the micro spring and at appropriately well-chosen distance scales and conditions, there is (are) approximately sinusoidal solution(s) for the problem (the variable turning points are collected in a very small interval of positions). This, as a simple and elementary plan, may be useful in controlling the Casimir stiction problem in micromechanical devices.
description: 5 pages, 2 figures
ÍNDICE DE TRANSPARÊNCIA COVID-19 Coronavírus: transparência em 90% dos estados brasileiros é insuficiente
Creators: name: OKBR
Publisher: name: Zenodo
Year: 2020
Subjects: Dados Abertos
Open data
Transparência
Covid-19
OKBR
Brasil
Calebe

description: Avaliação considerou conteúdo, formato e nível de detalhamento das informações divulgadas nos portais dos governos dos estados e do governo federal; 11 estados não publicam dados mínimos. Esse foi o primeiro boletim do ÍNDICE DE TRANSPARÊNCIA COVID-19.  Saiba mais no site: http://br.okfn.org
 EQUIPE RESPONSÁVEL PELO LEVANTAMENTO
 COORDENAÇÃO-GERAL
 Fernanda Campagnucci
 COLETA E ANÁLISE DE DADOS
 Camille Moura
 Fernanda Campagnucci
 REDAÇÃO E REVISÃO
 Murilo Machado
 Thiago Teixeira
description: Para saber mais sobre o Índice - https://zenodo.org/record/4027150#.X5DhK9BKhPY
Sonnenfleckenzeichnung Nr. 198.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.08.1995, 07:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Approximate Symmetry Analysis of a Class of Perturbed Nonlinear Reaction-Diffusion Equations
Creators: name: Nadjafikhah, Mehdi
name: Mahdavi, Abolhassan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In this paper, the problem of approximate symmetries of a class of non-linear reaction-diffusion equations called Kolmogorov-Petrovsky-Piskounov (KPP) equation is comprehensively analyzed. In order to compute the approximate symmetries, we have applied the method which was proposed by Fushchich and Shtelen [8] and fundamentally based on the expansion of the dependent variables in a perturbation series. Particularly, an optimal system of one dimensional subalgebras is constructed and some invariant solutions corresponding to the resulted symmetries are obtained.
description: 14 pages
Sonnenfleckenzeichnung Nr. 169.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.07.1995, 07:30, erstellt von Michele Bianda
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Stochastic approximation of score functions for Gaussian processes
Creators: name: Stein, Michael L.
name: Chen, Jie
name: Anitescu, Mihai
Publisher: name: arXiv
Year: 2013
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: We discuss the statistical properties of a recently introduced unbiased stochastic approximation to the score equations for maximum likelihood calculation for Gaussian processes. Under certain conditions, including bounded condition number of the covariance matrix, the approach achieves $O(n)$ storage and nearly $O(n)$ computational effort per optimization step, where $n$ is the number of data sites. Here, we prove that if the condition number of the covariance matrix is bounded, then the approximate score equations are nearly optimal in a well-defined sense. Therefore, not only is the approximation efficient to compute, but it also has comparable statistical properties to the exact maximum likelihood estimates. We discuss a modification of the stochastic approximation in which design elements of the stochastic terms mimic patterns from a $2^n$ factorial design. We prove these designs are always at least as good as the unstructured design, and we demonstrate through simulation that they can produce a substantial improvement over random designs. Our findings are validated by numerical experiments on simulated data sets of up to 1 million observations. We apply the approach to fit a space-time model to over 80,000 observations of total column ozone contained in the latitude band $40^{\circ}$-$50^{\circ}$N during April 2012.
description: Published in at http://dx.doi.org/10.1214/13-AOAS627 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Improving Quality of Clustering using Cellular Automata for Information retrieval
Creators: name: Sree, Pokkuluri Kiran
name: Babu, Inampudi Ramesh
Publisher: name: arXiv
Year: 2014
Subjects: subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: Clustering has been widely applied to Information Retrieval (IR) on the grounds of its potential improved effectiveness over inverted file search. Clustering is a mostly unsupervised procedure and the majority of the clustering algorithms depend on certain assumptions in order to define the subgroups present in a data set .A clustering quality measure is a function that, given a data set and its partition into clusters, returns a non-negative real number representing the quality of that clustering. Moreover, they may behave in a different way depending on the features of the data set and their input parameters values. Therefore, in most applications the resulting clustering scheme requires some sort of evaluation as regards its validity. The quality of clustering can be enhanced by using a Cellular Automata Classifier for information retrieval. In this study we take the view that if cellular automata with clustering is applied to search results (query-specific clustering), then it has the potential to increase the retrieval effectiveness compared both to that of static clustering and of conventional inverted file search. We conducted a number of experiments using ten document collections and eight hierarchic clustering methods. Our results show that the effectiveness of query-specific clustering with cellular automata is indeed higher and suggest that there is scope for its application to IR.
description: Journal of Computer Science 4 (2): 167-171, 2008,ISSN 1549-3636, 2008 Science Publications
title: Overleg Flexibel Storten: opvolgingsrapport 19. Periode januari 2021 – januari 2022
Creators: name: Stark, Jeroen
name: Vos, Gwendy
name: Plancke, Yves
Publisher: name: Flanders Hydraulics
Year: 2023

description: Title : WL Rapporten. Waterbouwkundig Laboratorium: Antwerpen. Volume : 00_031_39 Issue : Pagination : VII, 20 + 67p. bijl.
A growing braking index and spin-down swings for the pulsar PSR B0540-69
Creators: name: Espinoza, Cristóbal M.
name: Kuiper, Lucien
name: Ho, Wynn C. G.
name: Antonopoulou, Danai
name: Arzoumanian, Zaven
name: Harding, Alice K.
name: Ray, Paul S.
name: Younes, George
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The way pulsars spin down is not understood in detail, but a number of possible physical mechanisms produce a spin-down rate that scales as a power of the rotation rate ($\dotν\propto-ν^n$), with the power-law index $n$ called the braking index. PSR B0540-69 is a pulsar that in 2011, after 16 years of spinning down with a constant braking index of 2.1, experienced a giant spin-down change and a reduction of its braking index to nearly zero. Here, we show that following this episode the braking index monotonically increased during a period of at least four years and stabilised at ~1.1. We also present an alternative interpretation of a more modest rotational irregularity that occurred in 2023, which was modelled as an anomalous negative step of the rotation rate. Our analysis shows that the 2023 observations can be equally well described as a transient swing of the spin-down rate (lasting ~65 days), and the Bayesian evidence indicates that this model is strongly preferred.
description: 8 pages, 3 figures, accepted for publication by ApJL
Sonnenfleckenzeichnung Nr. 262.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.10.1995, 11:15, erstellt von Andrea Manna
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Depression, Co-Morbidity and Integrated Care
Creators: name: Meade, Tanya
name: Dickens, Geoffrey
name: Hay, Phillipa
name: Sarris, Jerome
name: Schmied, Virginia
name: Smith, Caroline
name: Lake, James
name: Linnell, Sheridan
name: Moustafa, Ahmed
name: Weidemann, Gabrielle
name: Conti, Janet
name: de Manincor, Michael
name: Ee, Carolyn
name: Firth, Joseph
name: Garrido, Sandra
name: Hohenberg, Mark
name: Perich, Tania
Publisher: name: Western Sydney University
Year: 2020

description: The purpose of this white paper is to describe a new integrated, collaborative and transdiagnostic approach to the care provided to people living with both depression and a co-occurring mental and/or physical illness. This includes the promotion of improved consumer partnerships to increase consumer self-efficacy and to recommend actions to educate and support healthcare providers.
This white paper outlines and addresses existing gaps in service for health consumers and identifies opportunities to build integrated models of care through collaboration between university and public and private health providers, informed by the lived experience of consumers. We highlight how Western Sydney University’s multi-disciplinary research can support and enable health services, communities and policy makers to address the diverse and complex needs of people living with both depression and another mental and/or physical illness in Western Sydney and beyond.
Sonnenfleckenzeichnung Nr. 237.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.09.1995, 09:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1995

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Efficient Analysis of Pattern and Association Rule Mining Approaches
Creators: name: Slimani, Thabet
name: Lazzez, Amor
Publisher: name: arXiv
Year: 2014
Subjects: subject: Databases (cs.DB)
subject: FOS: Computer and information sciences

description: The process of data mining produces various patterns from a given data source. The most recognized data mining tasks are the process of discovering frequent itemsets, frequent sequential patterns, frequent sequential rules and frequent association rules. Numerous efficient algorithms have been proposed to do the above processes. Frequent pattern mining has been a focused topic in data mining research with a good number of references in literature and for that reason an important progress has been made, varying from performant algorithms for frequent itemset mining in transaction databases to complex algorithms, such as sequential pattern mining, structured pattern mining, correlation mining. Association Rule mining (ARM) is one of the utmost current data mining techniques designed to group objects together from large databases aiming to extract the interesting correlation and relation among huge amount of data. In this article, we provide a brief review and analysis of the current status of frequent pattern mining and discuss some promising research directions. Additionally, this paper includes a comparative study between the performance of the described approaches.
description: 14 pages, 3 figures. arXiv admin note: text overlap with arXiv:1312.4800; and with arXiv:1109.2427 by other authors