cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Labor Power in the Repair Shop: Circuits of Repair Between Solidarity and Poor Economy
Creators: name: Graziano, Valeria
name: Trogal, Kim
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Dwellings--Maintenance and repair
subject: Sustainable development
subject: Consumption (Economics)
subject: Do-it-yourself work
subject: Upcycling (Waste, etc.)

description: This paper presents the findings of comparative research into the labor, organizational and spatial practices of a new kind of hybrid civic spaces that we refer to as “social impact-driven repair shops.” These are an emerging typology of urban spaces dedicated to repaired and up-cycled items that also go beyond the functions of a traditional shop. Significantly, these shops are run not purely for economic reasons, but rather to position themselves as local, socio-political interventions aiming to confront the environmental impacts of waste, support ethical and affordable consumption, alongside providing new opportunities for employment. We focused our fieldwork (2017–2019) on three such “repair shops”: ReTuna Återbruksgalleria in Sweden, The Loop in the United Kingdom and RiMaflow in Italy. We discuss the differing labor and spatial practices taking place within each while highlighting some of the tensions that emerge, and the implications for some of the wider debates in repair studies, “green work” and circular economies. We conclude by identifying two divergent and potentially antagonistic circuits of repair which we name “repair as solidarity” and “repair as poor economy,” which we propose as a lens to better grasp the different logics underpinning the transition to circular economies.
Efficient discovery of large magnetic anisotropy with thermodynamically stable materials via multi-objective Bayesian optimization
Creators: name: Nakamura, Kohei
name: Furuya, Daigo
name: Miura, Yoshio
name: Yamazaki, Takahiro
name: Foggiatto, Alexandre Lira
name: Iwasaki, Yuma
name: Kotsugi, Masato
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Physical Sciences not elsewhere classified
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: This study presents an efficient magnetic material exploring method with large magnetocrystalline anisotropy (MCA) and thermodynamic stability by combining multi-objective Bayesian optimization (MBO) with first-principles calculations. Focusing on six-layer tetragonal ordered alloys of rare-earth-free elements (Fe, Co, Ni, Cu), our approach optimizes material properties and process conditions within high-dimensional spaces. Explanatory variables derived from elemental and structural information were employed to enhance Bayesian optimization. Utilizing Gaussian process regression and dimensionality-reduced descriptors, we achieved efficient and robust exploration for precomputed dataset. As a result, MBO efficiently suggested the following three materials – Fe/Fe/Fe/Ni/Fe/Ni, Fe/Co/Fe/Co/Fe/Ni, and Fe/Co/Co/Fe/Ni/Ni – that exhibit thermodynamic stability while demonstrating an MCA value up to four times larger than that of L10-FeNi. The developed methodology accelerates material discovery and reduces resource demands, offering a scalable materials solution for optimizing functionality and process conditions across diverse material systems. This study accelerates advanced magnetic materials discovery by integrating multi-objective Bayesian optimization and first-principles calculations, uncovering rare-earth-free alloys with exceptional magnetocrystalline anisotropy and thermodynamic stability, enabling scalable materials development.
'You Will Be Like the Gods': The Conceptualization of Deity in the Hebrew Bible in Cognitive Perspective
Creators: name: McClellan, Daniel
Publisher: name: unknown
Year: 2022

description: This thesis has two primary goals: (1) to analyze the countours and extent of the generic category of deity in the Hebrew Bible, and (2) propose a semantic base for the term. It begins with a description of the fields associated with cognitive theory, and particularly cognitive linguistics. Chapter 2 examines the cognitive origins of notions of deity and discusses how this heritage is reflected within the biblical texts. The third chapter examines the conceptualization of Israel's prototypical deity, YHWH, beginning from the earliest divine profiles detectable within the text. In Chapter 4 the discussion returns to the generic notion of deity, highlighting references within the biblical text to deities other than YHWH. The conclusion synthesizes the different sections of the thesis, sketching the origins and development of the Hebrew Bible's representation of both prototypical and non-prototypical notions of deity. Implications for further research are then briefly discussed.
A new diaryl 1, 2-diketone from the heartwood of Dalbergia latifolia
Creators: name: Liu, Rong-hua
name: Wang, Ding-qing
name: Zhang, Pu-zhao
name: Shao, Feng
name: Chen, Lan-ying
name: Huang, Hui-lian
name: Lin, Shuai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: A new diaryl 1,2-diketone, named 1-(2,5-dihydroxy-4-methoxyphenyl)-2-phenylethane-1,2-dione (1), along with eight known compounds (2–9), were isolated from the heartwood of Dalbergia latifolia. They were identified on the basis of spectral data. Compounds 1–7 were obtained from the Dalbergia genus for the first time. Compounds 8 and 9 were firstly isolated from the plant. Compound 1 exhibited inactive against Staphylococcus aureus ATCC 6538 and Escherichia coli ATCC 21530 with the minimum inhibitory concentrations of 10.0 and 10.0 mg/mL, respectively.
'You Will Be Like the Gods': The Conceptualization of Deity in the Hebrew Bible in Cognitive Perspective
Creators: name: McClellan, Daniel
Publisher: name: Humanities Commons
Year: 2022

description: This thesis has two primary goals: (1) to analyze the countours and extent of the generic category of deity in the Hebrew Bible, and (2) propose a semantic base for the term. It begins with a description of the fields associated with cognitive theory, and particularly cognitive linguistics. Chapter 2 examines the cognitive origins of notions of deity and discusses how this heritage is reflected within the biblical texts. The third chapter examines the conceptualization of Israel’s prototypical deity, YHWH, beginning from the earliest divine profiles detectable within the text. In Chapter 4 the discussion returns to the generic notion of deity, highlighting references within the biblical text to deities other than YHWH. The conclusion synthesizes the different sections of the thesis, sketching the origins and development of the Hebrew Bible’s representation of both prototypical and non-prototypical notions of deity. Implications for further research are then briefly discussed.
Franz Marc as an Ethologist
Creators: name: Carey, Jean Marie
Publisher: name: unknown
Year: 2017
Subjects: subject: Germans--Social life and customs
subject: History
subject: Animal rights
subject: Painting
subject: Art

description: This thesis uses ethology as a framework to examine Franz Marc's paintings of animals. To perceive animals ethologically means acknowledging that animals feel, think, experience, and imagine the world. Ethology has come to include interpretive pursuits as well as traditional field studies, and as I show, Marc's practice encompassed both aspects of this evolving discipline. To establish the presence of ethology in the humanities I give a "case study" of what I call "retroactive ethology" in the work of J.M. Coetzee. I present an account of Marc's deep knowledge about real live animals. I offer an assessment of the inspiration Marc drew from Post-Impressionism and Egyptian art and show how Marc modernizes animal painting by demolishing longstanding conventions of the genre. I offer some ideas to more fully explain two important terms Marc uses, Animalisierung and Einfühlung. Throughout my paper I keep conceptual and historical observations closely tied to Marc's own words and images. Thus by reading and looking closely, we are able to see Marc as a dedicated and innovative ethologist whose implicit environmental commitment offers great comment upon contemporary discussions of the representation of the animal.
title: Sexualised Violence in the Experience of Adolescents
title: Results of a Representative Survey
titleType: Subtitle
Creators: name: Erkens, Christiane
name: Scharmanski, Sara
name: Hessling, Angelika
name: Federal Centre For Health Education (BZgA)
Publisher: name: Federal Centre for Health Education (BZgA)
Year: 2024
Subjects: subject: 10000 Social Sciences
subject: sexual abuse
subject: adolescence
subject: communication
subject: prevention
subject: sex education
subject: reproductive health
subject: sexual health
subject: reproduktive Gesundheit
subject: Adoleszenz
subject: Kommunikation
subject: Prävention
subject: sexueller Missbrauch
subject: sexual offences
subject: sexuelle Gewalt

description: Based on the ninth iteration of the Youth Sexuality Survey, prevalence rates of direct (hands-on) and indirect (hands-off) sexualised violence in adolescence, data on offenders and the disclosure behaviour of young people after victimization are described. The Federal Centre for Health Education (BZgA) in Germany has generated data regarding the prevalence of sexualised violence in adolescence by performing representative surveys on Youth Sexuality since 1998. In the ninth iteration, data show that adolescents and young adults experienced sexualised violence predominantly within their own peer group. Peers also play a significant role in responding to the disclosure of sexualised violence.
description: Scientific Article – Sexuality Education, Contraception and Family Planning
description: Face-to-face interview: CAPI/CAMI
Self-administered questionnaire: Computer-assisted (CASI)
A new ferulic acid ester from Rhodiola wallichiana var. cholaensis (Crassulaceae)
Creators: name: Song, Yaling
name: Zhou, Jianming
name: Wang, Xuejing
name: Xie, Xue
name: Zhao, Yiwu
name: Ni, Fuyong
name: Huang, Wenzhe
name: Wang, Zhenzhong
name: Xiao, Wei
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: A new ferulic acid ester, 6-feruloyloxyhexanoic acid (1), was isolated along with 10 known ones (2–11), from the concentrated water extract of Rhodiola wallichiana var. cholaensis. Their chemical structures were elucidated on the basis of extensive spectroscopic methods including Two-dimensional nuclear magnetic resonance (2D NMR) experiments. Compound 3 was isolated from this plant for the first time. The protective effects against H2O2-induced myocardial cell injury in cultured H9c2 cells were also evaluated. Compounds 1, 5 and 7–11 provided significant protective effects on H2O2-induced H9c2 cells injury at the concentration of 25 μg/mL. And the protective effects of compound 1 was also investigated by the oxygen–glucose deprivation/reperfusion (OGD/R) tests.
Isolation and structure elucidation of a new compound from the fungus Aspergillus flavipes PJ03-11
Creators: name: Liu, Fang
name: Chen, Gang
name: Zhang, Li-hua
name: Liu, Bing
name: Chen, Shaofei
name: Hua, Huiming
name: Bai, Jiao
name: Wang, Hai-feng
name: Pei, Yue-Hu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: A new diphenyl ether 3-methylpentyl-2, 4-dichloroasterrate (2), along with a known diphenyl ether butyl 2, 4-dichloroasterrate (1) were isolated from the metabolites of a wetland fungus Aspergillus flavipes. PJ03-11. The structures of 1 and 2 were determined by extensive NMR and HR–ESI–MS experiments. Compounds 1 and 2 showed weak cytotoxic activity, but both of them showed no antimicrobial activity.
SOLUTION OF THE NEUMANN PROBLEM FOR THE LAPLACE EQUATION IN A RECTANGLE BY THE FOURIER METHOD
Creators: name: Bogdan, Anna
Publisher: name: Zenodo
Year: 2024

description: The presented article discusses the Fourier method of separation of variables for solving the Laplace equation in a rectangular domain with Neumann boundary conditions. The main stages of this method are subsequently revealed:

1.       Representation of the general solution of the Laplace equation in a rectangular domain using Fourier series.

2.       Satisfying the Neumann boundary conditions using Fourier series.

3.       Constructing the solution of the Neumann problem, including the expansion of the boundary functions into Fourier series, determining the Fourier coefficients, and writing the final solution in the form of a Fourier series.

Analysis of the properties of the obtained solution, including its uniqueness, smoothness, continuity, and physical interpretation.
Eficiencia administrativa y gestión de riesgos. Escenario actual de las políticas de gestión documental
Creators: name: Ernesto Paz Enrique, Luis
name: García Salmon, Luis Alberto
name: Mena Mugica, Mayra Marta
Publisher: name: Humanities Commons
Year: 2019
Subjects: subject: Records--Management

description: La gestión documental como área de la administración está relacionada con la prevención de riesgos. Existe en el orden teórico y metodológico un déficit de literatura científica publicada en torno a los diferentes aspectos que dentro de la gestión documental se relacionan con la gestión de riesgos. Se identifica una carencia de fuentes que relacionen el impacto de las tecnologías de la información y las comunicaciones con la gestión documental. Se planteó como objetivo del estudio: establecer las relaciones entre las tecnologías de la información y las comunicaciones con las políticas de gestión documental y gestión de riesgos. Para la obtención de resultados se emplean métodos en los niveles teórico y empírico, fundamentalmente en el análisis documental. Se identifican los aspectos teóricos que inciden en la gestión documental y se establecen las relaciones entre gestión documental y gestión de riesgos.
Synthesis and in vitro antitumour activities of lupeol derivatives
Creators: name: Li, Weijie
name: Xiao, Yeyu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biochemistry
Cell Biology
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer
Hematology
Virology

description: Nine lupeol derivatives were synthesised and assayed in vitro for their antitumour activities against three human tumour cells lines, A549, LAC and HepG2. Of lupeol derivaties, six were new compounds, and five compounds against A549 cells, four compounds against HepG2 cells and three compounds against LAC cells were effective in reducing viability, and the most promising compounds 5, 6 and 9 exhibited high activities against lung and liver cancer cells, even higher activities than those of adriamycin.
Xylastriasan A, a new cytochalasan from the fungus Xylaria striata
Creators: name: Lei, Chuan-Wen
name: Yang, Zhi-Qin
name: Zeng, Yan-Ping
name: Zhou, Yun
name: Huang, Yi
name: He, Xin-Sheng
name: Li, Guo-You
name: Yuan, Xiao-Hong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Mental Health

description: Xylastriasan A (1), a new cytochalasan alkaloid with a rare 5/6/6/5/6 pentacyclic skeleton, and ergosterol (2) were isolated from the ethanol extract of fruiting bodies of the fungus Xylaria striata. Their structures were determined by analysis of their spectroscopic data. Compound 1 exhibited weak cytotoxic activity against HEPG2, B16 and A549 cell lines with IC50 values of 93.61, 85.61 and 91.58 μM, respectively. Ergosterol (2) potentiated pentobarbital-induced sleep by not only increasing the number of falling asleep and prolonging sleeping time but also reducing sleep latency at a dosage of 5 mg/kg.
El análisis de campos científicos a partir de la documentación. Una perspectiva sociológica
Creators: name: Ernesto Paz Enrique, Luis
name: Garcés González, Roberto
name: Núñez Jover, Jorge
Publisher: name: Humanities Commons
Year: 2019
Subjects: subject: Sociology
subject: FOS: Sociology

description: Existe en el orden teórico y metodológico una carencia de literatura científica publicada sobre las relaciones de comunicación científica escrita, como objeto de análisis de la sociología del conocimiento para analizar los campos de la ciencia. Se planteó como objetivo del estudio: identificar desde la sociología del conocimiento el sustento teórico que permita identificar las características de los campos científicos desde los documentos publicados. El presente estudio clasifica como descriptivo con aporte teórico. Para la obtención de resultados se emplearon métodos en los niveles teórico y empírico. En el nivel teórico se emplean los métodos analítico-sintético, histórico - lógico, inductivo-deductivo y sistémico - estructural. En el nivel empírico se emplea el análisis documental clásico. Se enuncian los presupuestos teóricos para el análisis de la producción científica a partir de la sociología del conocimiento. Se obtuvieron como resultados que el análisis de grandes volúmenes de documentos como de los artículos publicados en revistas científicas, da una medida objetiva sobre el conocimiento científico que se produce por campos del conocimiento. La sociología del conocimiento como perspectiva teórica y metodológica debe contemplar como uno de sus objetos de estudios la producción científica.
Into the infosphere: theory, literacy, and education for new forms of document
Creators: name: Bawden, David
name: Robinson, Lyn
Publisher: name: Universities of Osijek and Zadar
Year: 2016
Subjects: subject: Library science
subject: Information science
subject: Education

description: Coming changes in the information environment, particularly the infosphere and immersive documents are briefly reviewed, and their significance for library/information science considered, with a focus on topics addressed in the writings of Tatjana Aparac-Jelušić. Issues analysed include the nature of these new developments, new models of information behaviour and information literacy, consequences for education and professional training, and the relation between theory and practice.
Photonics4All - Eu Wide Outreach For Promoting Photonics To Young People, Entrepreneurs And The General Public
Creators: name: Haas, Dorothea
Publisher: name: Zenodo
Year: 2017
Subjects: Photonics
Light
outreach
science communication

description: The presentation gives an overview of the general idea of the Photonics4All Project. Photonics4All is an European outreach project, funded by the European Commission to promote photonics and light based technologies throughout the EU.
Safe_Storage_Pamphlet_JHCC – Supplemental material for Evaluating the Use of a Pamphlet as an Educational Tool to Improve Safe Firearm Storage in the Home
Creators: name: Hoops, Katherine E. M.
name: Hernandez, Emily
name: Ziegfeld, Susan
name: Nasr, Isam
name: Crifasi, Cassandra
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111403 Paediatrics
subject: FOS: Clinical medicine

description: Supplemental material, Safe_Storage_Pamphlet_JHCC for Evaluating the Use of a Pamphlet as an Educational Tool to Improve Safe Firearm Storage in the Home by Katherine E. M. Hoops, Emily Hernandez, Susan Ziegfeld, Isam Nasr and Cassandra Crifasi in Clinical Pediatrics
Principios para socializar y promocionar la lectura de libros científicos y docentes
Creators: name: Ernesto Paz Enrique, Luis
name: Hernández Alfonso, Eduardo Alejandro
name: Padrón López, Anieley
Publisher: name: Humanities Commons
Year: 2020
Subjects: subject: Bibliographies

description: Introducción: los libros científicos con fines docentes o para el aprendizaje, muestran resultados de investigación, experimentos y contenidos que permiten a los estudiantes adquirir conocimientos. En la literatura científica publicada se evidencia una carencia de publicaciones que fundamente los medios y formas que permitan realizar una correcta socialización y promoción de lectura para textos científicos y docentes. Objetivo: establecer los principios que deben regir la socialización y promoción de lectura de textos científicos con fines docentes. Métodos: el presente estudio clasifica como descriptivo con aporte práctico. Para la obtención de resultados se emplearon métodos en los niveles teórico y empírico. En el nivel teórico se emplean los métodos analítico - sintético, histórico-lógico, inductivo - deductivo y sistémico-estructural. En el nivel empírico se emplea el análisis documental clásico. Resultados: se plantean las formas y medios para la realización de una socialización y promoción de lectura de textos científicos con fines docentes tanto en el ámbito tradicional como en la web. Conclusiones: la socialización de los libros científicos y docentes debe realizarse en los medios tradicionales como en los digitales. La socialización puede realizarse a partir de tres formas: presencial, a través de un intermediario y por medio de la citación. Los medios tradicionales más empleados para la promoción y socialización de los libros científicos para la docencia son los eventos especializados. En la web se recomienda el uso de las redes sociales y académicas, los sitios web profesionales y los repositorios.
AJLM-19-0104-Table_3-LipidsGlycemic_in_T2D-REVISED-2020.03.12 – Supplemental material for The Role of Pulses in Cardiovascular Disease Risk for Adults With Diabetes
Creators: name: Lukus, Patricia K.
name: Doma, Katarina M.
name: Duncan, Alison M.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111799 Public Health and Health Services not elsewhere classified

description: Supplemental material, AJLM-19-0104-Table_3-LipidsGlycemic_in_T2D-REVISED-2020.03.12 for The Role of Pulses in Cardiovascular Disease Risk for Adults With Diabetes by Patricia K. Lukus, Katarina M. Doma and Alison M. Duncan in American Journal of Lifestyle Medicine
Supplementary_file_1 – Supplemental material for Perceptions and experiences of laws and regulations governing access to opioids in South, Southeast, East and Central Asia: A systematic review, critical interpretative synthesis and development of a conceptual framework
Creators: name: Clark, Joseph
name: Gnanapragasam, Sam
name: Greenley, Sarah
name: Pearce, Jessica
name: Johnson, Miriam
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental material, Supplementary_file_1 for Perceptions and experiences of laws and regulations governing access to opioids in South, Southeast, East and Central Asia: A systematic review, critical interpretative synthesis and development of a conceptual framework by Joseph Clark, Sam Gnanapragasam, Sarah Greenley, Jessica Pearce and Miriam Johnson in Palliative Medicine
Reviewer_2_v.1 – Supplemental material for Effect of post-extubation high-flow nasal cannula on reintubation in elderly patients: a retrospective propensity score-matched cohort study
Creators: name: Ryoung-Eun Ko
name: Park, Chul
name: Jimyoung Nam
name: Ko, Myeong Gyun
name: Na, Soo Jin
name: Ahn, Joong Hyun
name: Keumhee C. Carriere
name: Kyeongman Jeon
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 110203 Respiratory Diseases

description: Supplemental material, Reviewer_2_v.1 for Effect of post-extubation high-flow nasal cannula on reintubation in elderly patients: a retrospective propensity score-matched cohort study by Ryoung-Eun Ko, Chul Park, Jimyoung Nam, Myeong Gyun Ko, Soo Jin Na, Joong Hyun Ahn, Keumhee C. Carriere and Kyeongman Jeon in Therapeutic Advances in Respiratory Disease
La colateralidad de la enseñanza en línea de los programas en ciencias sociales en México
Creators: name: Ernesto Paz Enrique, Luis
name: Hernández Alfonso, Eduardo Alejandro
name: Tunal Santiago, Gerardo
Publisher: name: Humanities Commons
Year: 2021
Subjects: subject: Education

description: En las últimos dos décadas se ha masificado el uso de las Tecnologías de la Información y las Comunicaciones (TIC) en los procesos formativos y educativos que tienen lugar en la educación superior. El objetivo del presente artículo es exponer, emulando los corolarios a los que llegan Sokal y Bricmont en el libro Las imposturas intelectuales, los sinsentidos de la educación superior en línea que contradicen los criterios de calidad de la educación posmoderna. Métodos: Lo anterior se realiza a través de un primer estudio exploratorio, sustentado en 12 entrevistas aplicadas a docentes y estudiantes de seis programas de educación superior en línea, en ciencias sociales, que se encontraban operando en México, año 2016, en los niveles de licenciatura, maestría y doctorado. Los resultados arrojan que, pese a las ventajas que ofrece la educación en línea, ésta tiene de origen porosidades en las que se anquilosa la calidad de la educación en pro de la certificación. Conclusiones: La virtualización de la educación constituye una alternativa democratizadora del conocimiento, pero no exenta de reproducir las problemáticas de la educación superior presencial. Los actores educativos tienen que responsabilizarse de lo que enseñan o aprenden en una real socialización del conocimiento y no en una simulación de la participación.
The impact of KRAS mutational status on patient-reported outcomes in advanced non-small-cell lung cancer: a cross sectional study in France and Germany
Creators: name: Chouaid, Christos
name: Giannopoulou, Andromachi
name: Starry, Alexandra
name: Stollenwerk, Björn
name: Bozorgmehr, Farastuk
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Cancer
Science Policy

description: Health-related quality of life (HRQoL) studies in patients with advanced non-small-cell lung cancer (NSCLC) according to KRAS mutational status are limited. This study aimed to report real-world evidence on HRQoL outcomes based on KRAS mutational status in patients with advanced NSCLC tumors receiving second-line or later (2L+) treatment in France and Germany. In this real-world, non-interventional, cross-sectional, multicenter, patient-reported outcome (PRO) study conducted in France (15 contributing sites) and Germany (8 contributing sites), physicians enrolled adult patients with locally advanced and unresectable or metastatic NSCLC with known KRAS mutation status (KRAS G12C, KRAS non-G12C, or KRAS wildtype [WT]), who received a 2L + treatment. Study outcomes included sociodemographic characteristics; HRQoL evaluations based on EORTC Global Health Status QoL scores (QLQ-C30) and EQ-5D-5L scores. Data were analyzed descriptively. Of 156 enrolled patients, data from 149 patients were included in the final analysis (France, n = 103; Germany, n = 46). Median (quartile [Q]1, Q3) age was 67.0 (61.0, 71.0) years; 56.4% of patients were male. In total, 38.9% (n = 58), 26.2% (n = 39), and 34.9% (n = 52) of patients had tumors with KRAS G12C mutation, KRAS non-G12C mutation and WT KRAS, respectively. Mean (±SD) QLQ-C30 Global Health Status QoL scores were 56.99 (20.30) for the overall population, and 56.03 (22.55), 58.97 (18.67) and 56.57 (19.05) for KRAS G12C, non-G12C, and WT subpopulations. In the overall population, moderate-to-extreme problems were reported in all EQ-5D-5L dimensions (range: overall population, 15.5%–39.6%; KRAS G12C, 15.6%–46.6%; non-G12C, 7.8%–23.1%; WT, 21.1%–44.2%). HRQoL was broadly similar across KRAS G12C, non-G12C, and WT subpopulations.
Supplemental Material, Table_S1 - Curcumin Inhibits the Migration and Invasion of Non-Small-Cell Lung Cancer Cells Through Radiation-Induced Suppression of Epithelial-Mesenchymal Transition and Soluble E-Cadherin Expression
Creators: name: Deng, Xinzhou
name: Chen, Chunli
name: Wu, Feng
name: Qiu, Li
name: Ke, Qing
name: Sun, Renhuang
name: Duan, Qiwen
name: Luo, Ming
name: Luo, Zhiguo
Publisher: name: SAGE Journals
Year: 2020
Subjects: Oncology and Carcinogenesis not elsewhere classified
Radiology and Organ Imaging
Biochemistry

description: Supplemental Material, Table_S1 for Curcumin Inhibits the Migration and Invasion of Non-Small-Cell Lung Cancer Cells Through Radiation-Induced Suppression of Epithelial-Mesenchymal Transition and Soluble E-Cadherin Expression by Xinzhou Deng, Chunli Chen, Feng Wu, Li Qiu, Qing Ke, Renhuang Sun, Qiwen Duan, Ming Luo and Zhiguo Luo in Technology in Cancer Research & Treatment
Supplemental Material, sj-pdf-1-jcr-10.1177_0022002720969796 - Adverse Rainfall Shocks and Civil War: Myth or Reality?
Creators: name: Maertens, Ricardo
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 220104 Human Rights and Justice Issues
subject: FOS: Philosophy, ethics and religion
subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material, sj-pdf-1-jcr-10.1177_0022002720969796 for Adverse Rainfall Shocks and Civil War: Myth or Reality? by Ricardo Maertens in Journal of Conflict Resolution
Supplementary_material_online_supp – Supplemental material for Exploring the Cost Effectiveness of Shared Decision Making for Choosing between Disease-Modifying Drugs for Relapsing-Remitting Multiple Sclerosis in the Netherlands: A State Transition Model
Creators: name: Kremer, Ingrid E. H.
name: Hiligsmann, Mickael
name: Carlson, Josh
name: Zimmermann, Marita
name: Jongen, Peter J.
name: Evers, Silvia M. A. A.
name: Petersohn, Svenja
name: Pouwels, Xavier G. L. V.
name: Bansback, Nick
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, Supplementary_material_online_supp for Exploring the Cost Effectiveness of Shared Decision Making for Choosing between Disease-Modifying Drugs for Relapsing-Remitting Multiple Sclerosis in the Netherlands: A State Transition Model by Ingrid E. H. Kremer, Mickael Hiligsmann, Josh Carlson, Marita Zimmermann, Peter J. Jongen, Silvia M. A. A. Evers, Svenja Petersohn, Xavier G. L. V. Pouwels and Nick Bansback in Medical Decision Making
Supplemental_Tables – Supplemental material for Evaluations of a Previous Day as a Pathway Between Personality and Healthy Cognitive Aging
Creators: name: Sutin, Angelina R.
name: Stephan, Yannick
name: Aschwanden, Damaris
name: Luchetti, Martina
name: Strickhouser, Jason E.
name: Terracciano, Antonio
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110308 Geriatrics and Gerontology
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, Supplemental_Tables for Evaluations of a Previous Day as a Pathway Between Personality and Healthy Cognitive Aging by Angelina R. Sutin, Yannick Stephan, Damaris Aschwanden, Martina Luchetti, Jason E. Strickhouser and Antonio Terracciano in Journal of Aging and Health
Antes-Ahora: el diseño de bien público para la educación e inclusión social
Creators: name: Ernesto Paz Enrique, Luis
name: Hernández Alfonso, Eduardo Alejandro
Publisher: name: Humanities Commons
Year: 2017
Subjects: subject: Sex

description: La lucha contra la homofobia debe constituir prioridad internacional. Para el diseño de productos se emplean tecnologías de la información y las comunicaciones. La investigación favorece la educación y conciencia crítica para el respeto a diversidad sexual. El estudio que se presenta y clasifica como investigación aplicada; se emplearon métodos en los niveles teóricos y empírico. Se plantea como objetivo general: diseñar una serie de carteles de bien público para visibilizar los resultados de Cuba respecto a la inclusión social de personas sexualmente diversas. Se diseña una serie de tres carteles de bien público denominada Antes-Ahora orientada a fortalecer las campañas educativas en el país a favor de la diversidad sexual.
Assessing the economic impact and healthcare resource utilization of inpatient pneumococcal disease among adults: a French national claims database study
Creators: name: Bailey, M. Doyinsola
name: Farge, Gaëlle
name: Brunel, Manon Breau
name: Mohanty, Salini
name: Roy, Gem
name: de Pouvourville, Gérard
name: de Wazieres, Benoit
name: Janssen, Cécile
name: Tauty, Solenne
name: Bugnard, Françoise
name: Goguillot, Mélanie
name: Bénard, Stève
name: Johnson, Kelly D.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Pneumococcal diseases (PD) caused by Streptococcus pneumoniae include invasive PD (IPD) and non-bacteremia pneumococcal pneumonia (NBPP). Current French vaccination guidelines focus on patients with underlying medical conditions (UMC) who are at a higher risk of PD. This study describes the healthcare resource utilization (HCRU) and economic burden of inpatient PD in French adults, to inform vaccination guidelines, especially among vulnerable subpopulations at increased risk of PD. A retrospective study utilizing the French administrative healthcare database (SNDS) was conducted among adults with an inpatient PD episode between 2015 and 2018. HCRU and costs were described per inpatient PD episode, according to patient risk level, type of PD, and age group. Between 2015 and 2018, 42,466 inpatient PD episodes were identified. Most of the inpatient PD episodes (73.7%) occurred in patients with UMCs. The median (Q1–Q3) cost per inpatient PD episode seemed higher among medium-risk patients (€14,863 (€7,875–€30,434)) than among low-risk (€11,034 (€5,803–€23,098)) and high-risk patients (€13,258 (€7,143–€26,815)). Cost per inpatient PD episode did not seem to increase steadily with age, however, ≥65 patients represented 59.5% of all inpatient PD episodes and 52.3% of the overall inpatient PD episodes cost (€548,224,569 out of €1,049,214,069). Due to constraints of the SNDS dataset, results are limited to inpatient episodes of PD and may not be representative of all PD episodes in France. This large, retrospective study highlights a substantial economic burden associated with inpatient PD in France, especially among individuals with UMCs and those aged 65 years or over. These results emphasize the need to improve prevention strategies, especially among older patients, regardless of their risk level.
Budget impact of introducing glofitamab for treatment of relapsed or refractory diffuse large B-cell lymphoma after two or more lines of systemic therapy in the United States
Creators: name: Mahmoudjafari, Zahra
name: Li, Jia
name: Bercaw, Eric
name: Parisé, Hélène
name: Bognar, Katalin
name: Wang, Si-Tien
name: Masaquel, Anthony
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Glofitamab is a T-cell engaging bispecific monoclonal antibody that was granted accelerated approval from the United States Food and Drug Administration for adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), not otherwise specified or large B-cell lymphoma arising from follicular lymphoma, after ≥2 lines of systemic therapy (3L+). A budget impact model was developed for a hypothetical blended commercial/Medicare health plan with 1,000,000 members. Comparators were axicabtagene ciloleucel (Axi-cel), lisocabtagene maraleucel (Liso-cel), tisagenlecleucel (Tisa-cel), loncastuximab tesirine, polatuzumab vedotin + bendamustine + rituximab, rituximab + gemcitabine + oxaliplatin, tafasitamab + lenalidomide, and epcoritamab (Epcor). Total costs included those for drugs, wastage, administration, grade ≥3 adverse reactions, and all-grade cytokine release syndrome) and routine care. Market shares were based on internal projections and expert opinions. Total and per-member per-month (PMPM) net budget impacts over 3 years were calculated. Approximately nine patients were projected to be eligible for 3L + DLBCL treatment in a health plan of 1,000,000 members. The introduction of glofitamab as a treatment option resulted in estimated total and PMPM cost savings of $728,697 and –$0.0202, respectively, over 3 years. Costs were reduced across all cost categories but particularly in drug costs. Among the newer therapies, total 3-year cost per treated patient was lowest for glofitamab: $226,658 versus Tisa-cel = $564,113; Axi-cel = $540,002; Liso-cel = $516,272; and Epcor = $335,293. Across all sensitivity analyses, the inclusion of glofitamab had minimal PMPM budget impact, ranging from –$0.0256 to –$0.0108. With the lowest 3-year total cost per treated patient among the newer therapies, glofitamab being an available option in the 3L + DLBCL market is estimated to save a hypothetical 1,000,000-member health plan $728,697 in cumulative total costs and $0.0202 in PMPM costs over 3 years. Glofitamab is a new treatment for a common type of blood cancer that does not respond to at least two other treatments. This analysis estimated the change in a health plan’s spending over a 3-year period if it covered and used glofitamab rather than epcoritamab or other options and found that the plan’s 3-year spending decreased by $0.02 per plan member per month in overall costs.
Governing the science of selection: the psychological sciences, 1921–45
Creators: name: White, Alice
Publisher: name: unknown
Year: 2017
Subjects: subject: History
subject: Great Britain
subject: Military history
subject: Science

description: The psychological sciences were deployed in Second World War Britain on an unprecedented scale in the hopes of managing the mobilised population. This chapter traces three groups of psychologists: Bartlett's experimental psychologists from Cambridge, psychologists from the National Institute of Industrial Psychology (NIIP), and the Tavistock Clinic's psychoanalysts. It follows their work from peacetime, in the lab, factory, and clinic, to wartime negotiations over how their work should be conducted. Each group had distinct views on the ideal relationship of scientists to military patrons, from disinterested advisors to consultants to involved collaborators. Psychologists' diverse views on what was valuable in a person shaped (and was shaped by) their methods, revealing three very different approaches to the creation of a science of selection.
A prospective cohort study estimating total pre-surgical healthcare costs before and two-year total societal costs after resective brain surgery, and quality of life of patients with drug-resistant epilepsy undergoing surgery
Creators: name: Maas, L.
name: Peeters, C. B. C. M.
name: Hiligsmann, M.
name: van Kuijk, S. M. J.
name: Tousseyn, S.
name: Kellenaers, J.
name: van Mastrigt, G. A.P.G.
name: Vlooswijk, M.C.G.
name: Klinkenberg, S.
name: Wagner, L.
name: Nelissen, J.
name: Schijns, O. E. M. G.
name: Majoie, H. J. M.
name: Rijkers, K.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: In contrast to clinical effectiveness of resective epilepsy surgery (RES) for patients with drug-resistant epilepsy, societal costs of RES is still unclear. The aim of this study was to report on total societal costs up until two years after surgery and analyse the trend of post-surgical costs over time. Secondary objectives included assessing quality of life (QoL) changes and identifying determinants of post-surgical costs. Data were derived from the patients’ entire medical history based on hospital files and accompanied by validated questionnaires before and 3-, 6-, 12-, and 24-months post-surgery to additionally include medical consumption outside of the hospital, productivity losses and gains, and QoL. To explore the trend of post-surgical costs over time and identify determinants of post-surgical costs, linear mixed effects and linear regression models were performed. The study included 44 patients. Mean complete costs from diagnostics and treatment strategies in the period before referral for pre-surgical evaluation up until two years after RES were €121,856 (Interquartile range = €76,058−€137,027). Post-surgical costs significantly decreased 12 months (mean 3-month difference = €−6,675, p = 0.000) and 24 months (mean 3-month difference = €−7,690, p = 0.000) after surgery compared to 3 months before surgery. Higher post-surgical costs were associated with a clinically relevant increase in disease-specific QoL after RES (p = 0.000), previous ketogenic diet (p = 0.005), RES in the left hemisphere (p = 0.014), previous RES (p = 0.007), and higher diagnostics and treatment strategies costs before referral for pre-surgical evaluation (p = 0.021). For disease-specific and generic QoL, 20 (45%) patients reached a clinically relevant QoL increase two years after surgery compared to before RES. In conclusion, RES leads to significant reduction in costs 2 years post-surgery. History of RES and ketogenic diet, clinically relevant disease-specific QoL increase, surgery in the left hemisphere, and higher costs of diagnostics and treatment strategies before referral for pre-surgical evaluation were significant determinants for higher post-surgical costs after RES.
A prospective cohort study estimating total pre-surgical healthcare costs before and two-year total societal costs after resective brain surgery, and quality of life of patients with drug-resistant epilepsy undergoing surgery
Creators: name: Maas, L.
name: Peeters, C.B.C.M.
name: Hiligsmann, M.
name: vanKuijk, S.M.J.
name: Tousseyn, S.
name: Kellenaers, J.
name: vanMastrigt, G. A.P.G.
name: Vlooswijk, M.C.G.
name: Klinkenberg, S.
name: Wagner, L.
name: Nelissen, J.
name: Schijns, O.E.M.G.
name: Majoie, H.J.M.
name: Rijkers, K.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: In contrast to clinical effectiveness of resective epilepsy surgery (RES) for patients with drug-resistant epilepsy, societal costs of RES is still unclear. The aim of this study was to report on total societal costs up until two years after surgery and analyse the trend of post-surgical costs over time. Secondary objectives included assessing quality of life (QoL) changes and identifying determinants of post-surgical costs. Data were derived from the patients’ entire medical history based on hospital files and accompanied by validated questionnaires before and 3-, 6-, 12-, and 24-months post-surgery to additionally include medical consumption outside of the hospital, productivity losses and gains, and QoL. To explore the trend of post-surgical costs over time and identify determinants of post-surgical costs, linear mixed effects and linear regression models were performed. The study included 44 patients. Mean complete costs from diagnostics and treatment strategies in the period before referral for pre-surgical evaluation up until two years after RES were €121,856 (Interquartile range=€76,058-€137,027). Post-surgical costs significantly decreased 12 months (mean 3-month difference=€-6,675, p = 0.000) and 24 months (mean 3-month difference=€-7,690, p = 0.000) after surgery compared to 3 months before surgery. Higher post-surgical costs were associated with a clinically relevant increase in disease-specific QoL after RES (p = 0.000), previous ketogenic diet (p = 0.005), RES in the left hemisphere (p = 0.014), previous RES (p = 0.007), and higher diagnostics and treatment strategies costs before referral for pre-surgical evaluation (p = 0.021). For disease-specific and generic QoL, 20 (45%) patients reached a clinically relevant QoL increase two years after surgery compared to before RES. In conclusion, RES leads to significant reduction in costs 2 years post-surgery. History of RES and ketogenic diet, clinically relevant disease-specific QoL increase, surgery in the left hemisphere, and higher costs of diagnostics and treatment strategies before referral for pre-surgical evaluation were significant determinants for higher post-surgical costs after RES.
Silence and Selection: the "trick cyclist" at the War Office Selection Boards
Creators: name: White, Alice
Publisher: name: Routledge
Year: 2016
Subjects: subject: History
subject: Great Britain
subject: Military history
subject: Science

description: In 1939, psychiatrists wrote to the War Office of Britain to offer up their services in the likely event of war. The response? A resounding silence. This unpromising start marked the first words (and the first silence) in a discussion of psychological science that would span the war. The " trick cyclist " , or psychiatrist, was a controversial figure during World War II. At War Office Selection Boards, psychiatrists sought a voice to speak not only of the deviant populations that they conventionally studied, but also to discuss normal and even superior members of society. Winston Churchill, amongst others, was not at all sure about this, noting the 'immense amount of harm' they might do. Suspicions of 'these gentlemen' and their affiliation with taboos such as sex, resulted in a number of enquiries into, and limitations upon, their work at Selection Boards during the war (Churchill, 2010, p.815). The most contentious site of such negotiation and contention was the psychiatric interview, where psychiatrists assessed soldiers put forward for commission. This chapter analyses the the technique of the psychiatric interview at the War Office Selection Board as the point of intersection between Army authorities, soldiers, and psychiatrists: those commissioning science, those subject to the gaze of science, and those practicing science.