cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Impact of Breast Cancer and its Therapy on Bone Density
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Survival of women with breast cancer continues to improve. Thus, breast cancer survivors (BCS) must have more knowledge about how breast cancer and its treatment affect their long-term health. Menopause is a universal female event; consequences may include osteoporosis. Yet there is disturbing lack of information about how BCS experience menopause, whether BCS develop osteoporosis, and what can be done about it. This application seeks to: 1) allow a highly-qualified clinician to become a researcher in the field of menopause and osteoporosis in BCS; and 2) in the context of this training, to undertake specific research focused on osteoporosis in BCS. The candidate will acquire the skills to continue work in the intersection between breast cancer, menopause, and long-term health.

 The central hypotheses of the research are:

 -Higher estrogen levels may put a woman at higher risk of breast cancer, but at the same time might help her build better bone mass. Thus, do women with breast cancer start out with better bone health (higher bone density) than women without breast cancer?

 -Do women with breast cancer lose bone at different speeds after menopause compared to women without breast cancer?

 -Can blood hormone levels predict the rate at which BCS lose bone?

 In order to facilitate the PI's career transition the candidate will: obtain a Masters in Clinical Epidemiology; undertake a strong breast cancer mentoring program with Dr. Patricia Ganz, to obtain in-depth understanding of the how breast cancer and its therapy affects the health and well-being of women; and undertake mentorship in research methods and osteoporosis with Dr. Gail Greendale.

 To address the 3 questions outlined above, the candidate will be mentored in the conduct of three data analyses that focus on bone density in breast cancer survivors. She will use already-collected data from the Cancer and Menopause study, an ongoing study of breast cancer survivors led by Drs. Ganz and Greendale.

 The good news is that women are living longer after breast cancer treatment. The bad news is that many of their questions about long term health, particularly related to menopause, remain unanswered. This project is innovative in that it will train a clinical researcher who will focus her research career on this under-studied area of survivorship. The innovative multidisciplinary approach to the training and the research outlined here, as well as the unique breast cancer survivor data base available to the candidate, are also critical elements of the project.
Paranura bisetosa Deharveng 1989
Creators: name: Jantarit, Sopark
name: Bedos, Anne
name: Deharveng, Louis
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Collembola
Neanuridae
Paranura
Paranura bisetosa

description: 50. Paranura bisetosa Deharveng, 1989
Source: Deharveng (1989), Bedos (1994), Rojanavongse et al. (unpublished report). Type deposition: LEITT. Distribution in Thailand. Chiang Mai (N). Habitat: litter under reeds at 500 m. in Doi Chiang Dao. Distribution outside Thailand. Only known from Thailand (Doi Chiang Dao).
description: Published as part of Jantarit, Sopark, Bedos, Anne & Deharveng, Louis, 2016, An annotated checklist of the Collembolan fauna of Thailand, pp. 301-360 in Zootaxa 4169 (2) on page 316, DOI: 10.11646/zootaxa.4169.2.4, http://zenodo.org/record/265801
Inventaire du fonds Bastaire de littérature populaire et infantine [version 1]. Crès Hachette (après 1914)
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024

description: Numérisation ICB CollEx-Persée AAP20212022
description: Les titres sont ceux donnés par Jean Bastaire. Les dates indiquées ont été établies depuis un courrier de Jean à Michel Bastaire qui lui demandait de dresser l'inventaire. Et la date de fin correspond à la donation et à la publication de Lectures englouties. Listes manuscrites de la collection établie par Jean Bastaire et Michel Bastaire ; Jean sous forme de livrets thématiques et feuilles volantes au format A5. Michel a consigné les titres dans un carnet bloc type Rhodia format A6.
description: Source: Fonds Bastaire Université Clermont Auvergne (Bas-G08_D087)
description: Relation: http://www.calames.abes.fr/pub/ms/_631139801_Bas-G08_D087
description: created: 1993/2008
Additional file 1: of Estimating the impact of post randomization changes in staff behavior in infection prevention trials: a mathematical modeling approach
Creators: name: Lofgren, Eric
Publisher: name: Figshare
Year: 2017
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: Ordinary differential equation representation of a mathematical model of MRSA acquisition in an intensive care unit. (DOCX 76 kb)
Fecal IgA, Antigen Absorption, and Gut Microbiome Composition Are Associated With Food Antigen Sensitization in Genetically Susceptible Mice
Creators: name: Steinbach, Erin C.
name: Kesselring, Janelle R.
name: Mucha, Peter J.
name: Johnson-Weaver, Brandi T.
name: Ferris, Martin T.
name: Immormino, Robert M.
name: Moran, Timothy P.
name: Staats, Herman F.
name: Hinton, Andrew L.
name: Orgel, Kelly A.
name: Kulis, Michael D.
name: Smeekens, Johanna M.
name: Burks, A. Wesley
name: Azcarate-Peril, M. Andrea
Publisher: name: Frontiers
Year: 2021

description:
Food allergy is a potentially fatal disease affecting 8% of children and has become increasingly common in the past two decades. Despite the prevalence and severe nature of the disease, the mechanisms underlying sensitization remain to be further elucidated. The Collaborative Cross is a genetically diverse panel of inbred mice that were specifically developed to study the influence of genetics on complex diseases. Using this panel of mouse strains, we previously demonstrated CC027/GeniUnc mice, but not C3H/HeJ mice, develop peanut allergy after oral exposure to peanut in the absence of a Th2-skewing adjuvant. Here, we investigated factors associated with sensitization in CC027/GeniUnc mice following oral exposure to peanut, walnut, milk, or egg. CC027/GeniUnc mice mounted antigen-specific IgE responses to peanut, walnut and egg, but not milk, while C3H/HeJ mice were not sensitized to any antigen. Naïve CC027/GeniUnc mice had markedly lower total fecal IgA compared to C3H/HeJ, which was accompanied by stark differences in gut microbiome composition. Sensitized CC027/GeniUnc mice had significantly fewer CD3+ T cells but higher numbers of CXCR5+ B cells and T follicular helper cells in the mesenteric lymph nodes compared to C3H/HeJ mice, which is consistent with their relative immunoglobulin production. After oral challenge to the corresponding food, peanut- and walnut-sensitized CC027/GeniUnc mice experienced anaphylaxis, whereas mice exposed to milk and egg did not. Ara h 2 was detected in serum collected post-challenge from peanut-sensitized mice, indicating increased absorption of this allergen, while Bos d 5 and Gal d 2 were not detected in mice exposed to milk and egg, respectively. Machine learning on the change in gut microbiome composition as a result of food protein exposure identified a unique signature in CC027/GeniUnc mice that experienced anaphylaxis, including the depletion of Akkermansia. Overall, these results demonstrate several factors associated with enteral sensitization in CC027/GeniUnc mice, including diminished total fecal IgA, increased allergen absorption and altered gut microbiome composition. Furthermore, peanuts and tree nuts may have inherent properties distinct from milk and eggs that contribute to allergy.
Molecular Design for Prevention of Breast Cancer Progression
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: We propose to engineer a molecule that will be ideally suited for arresting metastatic progression of breast cancer. This molecule will be designed to deliver a destructive radioisotope only to breast tumor cells. Both single metastatic cells and large tumors will be efficiently targeted. When used in multiple periodic administrations, the molecule should be able to prevent the recurrence of metastatic breast cancer. Therefore, the success of this project should provide a means to reduce the mortality from breast cancer by prolonging or saving the lives of those afflicted with metastatic disease.

 Our proposed IFab2 molecule will be related to "antibodies," which are natural defense molecules that find their targets with exquisite specificity. Previous human clinical trials have demonstrated the ability of antibodies (attached to radioisotopes) to target metastatic breast carcinoma cells but they also point to some problems: 1) the large size of antibodies leads to suboptimal targeting rates and to poor penetration of large tumors, and 2) antibodies can stick to healthy defense cells. This sticking is desirable in the natural situation as a means to summon defense cells to destroy foreign invaders tagged by antibodies. In the clinical setting however, this can result in the destruction of healthy cells, in diminishing the rate of delivery of the radioisotope to tumor cells, and in other undesirable side effects. The proposed iFab2s will find their targets like antibodies but will diffuse more rapidly to metastatic sites. IFab2s will also lack the regions that bind healthy defense cells while retaining the high affinity and specificity for breast tumor cells.

 IFab2s do not occur naturally and cannot be prepared directly from antibodies. Essentially they will look like two connected and inverted antibody fragments. We propose to optimize their design, which will be encoded by a single engineered gene. This gene will direct the production of iFab2s for breast cancer treatment in unlimited quantities and ready for attachment to a radioisotope. The first IFab2s will have the targeting properties of our best humanized antibodies, BrE-3 and Mc3, which have been proven to target and specifically destroy human breast carcinomas. If successfully designed, these IFab2s could be used to completely arrest metastatic progression with negligible damage to non-tumor tissues.
Municipal managers’ responsiveness to public demands
Creators: name: Liao, Yuguo
Publisher: name: No Publisher Supplied
Year: 2013

description: Public responsiveness, or bureaucratic responsiveness to citizen demands, is central in public administration theories. It has become a key concept regarding the appropriate role of bureaucracy and professional administrators in a democratic political system. In city management, responsiveness to public demands should be particularly addressed given the fact that local professionals have constant and direct contact with local residents.   This dissertation builds on existing studies that identify the determinants of public responsiveness. One significant research gap of existing researches was noticed, that is, few studies have included public administrators’ willingness into the analysis framework. Current studies have identified organizational factors, environmental factors, features of policy clients and problem intensity as predictors of public responsiveness. However, examining public responsiveness without assessing individuals’ willingness would neglect their own interpretation and interaction with the environmental and institutional factors. It is at the individual level that the functioning of environmental and organizational factors is enacted.   This dissertation project focuses municipal managers’ public responsiveness in the formulation of local budgets. The main research questions of this study include: (1) What is the actual level of municipal managers’ public responsiveness? (2) Given the importance of municipal managers’ attitudes, how can we foster their favorable attitude toward public responsiveness? In other words, what are the determinants of their attitudinal willingness to be responsive to public demands? (3) What are the determinants of municipal manages’ public responsiveness? How do municipal managers’ attitudinal and behavioral willingness connect environmental and organizational factors in determining their public responsiveness?   The data in this dissertation was collected from New Jersey and Pennsylvania municipal managers. The seemingly unrelated regression (SUR) result indicates that the factor with the strongest impact on municipal managers’ attitudinal willingness is successful implementation and practices in other municipalities. It highlights the importance of social learning in acquiring and assimilating social knowledge. In the public responsiveness model, the structural equation modeling (SEM) result confirms that a thorough understanding of the determinants of public responsiveness cannot be separated from examining municipal managers’ attitudinal and behavioral willingness. It further suggests that environmental and organizational factors tend to enhance municipal managers’ public responsiveness (1) through institutional constraints; (2) through enhancing their perceived behavioral control.
Paha Dajoz 1984
Creators: name: ALEKSEEV, VITALII
name: MCKELLAR, RYAN C.
name: BUKEJS, ANDRIS
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Zopheridae
Paha

description: Genus Paha Dajoz, 1984
Type species: Paha guadalupensis Dajoz, 1984
Taxonomic assignment. The studied inclusion is placed in the tribe Synchitini within the subfamily Colydiinae based on the combination of the following characters: (1) dorsally concealed antennal insertions; (2) antennae clubbed, lacking scale-like setae; (3) procoxal cavities open posteriorly; (4) all tarsi tetramerous, not dilated; (5) protibiae without apical spurs; and (6) metacoxae narrowly separated by triangular process of abdominal ventrite 1. The new extinct species belongs to the genus Paha based on its: 10-segmented antennae with 1-segmented, rounded club; antennal groove ventrad eye absent; antennomere 3 not twice as long as antennomere 4; scutellary striole absent; dorsum lacking obvious pubescense (setation short and fine, visible under high magnification only); pronotal disc with elevated central area limited by two parallel longitudinal carinae; odd elytral intervals carinate; and elytral striae with rows of elongate granules.
description: Published as part of ALEKSEEV, VITALII, MCKELLAR, RYAN C. & BUKEJS, ANDRIS, 2024, A revision and addition to Zopheridae (Coleoptera: Tenebrionoidea) in Baltic amber: possible connections between modern Holarctic distributions and Eocene ' amber forests', pp. 201-247 in Zootaxa 5536 (2) on page 210, DOI: 10.11646/zootaxa.5536.2.1, http://zenodo.org/record/14033618
Paranura chiangdaoensis Deharveng 1989
Creators: name: Jantarit, Sopark
name: Bedos, Anne
name: Deharveng, Louis
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Collembola
Neanuridae
Paranura
Paranura chiangdaoensis

description: 51. Paranura chiangdaoensis Deharveng, 1989
Source: Deharveng (1989), Bedos (1994), Rojanavongse et al. (unpublished report). Type deposition: LEITT. Distribution in Thailand. Chiang Mai (N). Habitat: litter at 700 m. in Doi Chiang Dao forest. Distribution outside Thailand. Only known from Thailand (Doi Chiang Dao).
description: Published as part of Jantarit, Sopark, Bedos, Anne & Deharveng, Louis, 2016, An annotated checklist of the Collembolan fauna of Thailand, pp. 301-360 in Zootaxa 4169 (2) on page 316, DOI: 10.11646/zootaxa.4169.2.4, http://zenodo.org/record/265801
Additional file 1: of Estimating the impact post randomization changes in staff behavior in infection prevention trials: a mathematical modeling approach
Creators: name: Lofgren, Eric
Publisher: name: Figshare
Year: 2017
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: Ordinary differential equation representation of a mathematical model of MRSA acquisition in an intensive care unit. (DOCX 76 kb)
Mobile Phone Platform for Genomic Disease Detection
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Mobile Phone Platform for Genomic Disease Detection ABSTRACT Infectious diseases are a major cause of health problems and death worldwide. Effective therapeutics have been developed for many bacterial and viral pathogens, but the emergence of drug resistance and increased virulence means that these diseases remain a constant threat to both developed and developing countries. Since methods for identifying drug resistant infections are not widespread, especially in developing countries, we propose to develop a mobile platform for genetic identification of infectious diseases agents that is both rapid and low cost. Our proposed technology combines an isothermal nucleic amplification technique (LAMP) with mobile phone based fluorescence and bioluminescence detection and analysis, and we will demonstrate the diagnostic potential of our approach by creating the first LAMP test for multidrug resistant tuberculosis (MDR-TB) that can be completed on a mobile phone in under one hour. This project brings together the expertise of three UC-based laboratory groups: isothermal LAMP technology from LLNL, mobile microscopy technology from UC Berkeley, and international TB diagnosis and treatment experience from UCSF. Current methods for TB screening are either simple but have low sensitivity and are unable to identify drug resistant strains (microscopy using Ziehl-Neelson or Auramine-O staining), have high sensitivity but take weeks to obtain results (mycobacterial culture), or are expensive and inappropriate for mobile use (PCR-based techniques such as the Cepheid GeneXpert). We plan to leverage the communications, computing, geo-tagging, and optical imaging capabilities of mobile phones, together with the high specificity and sensitivity of laboratory-based LAMP assays, to create a unique and portable system for rapid pathogen detection with applications to MDR-TB diagnosis, as well as a wide variety of infectious disease and biosecurity targets worldwide.
If you believe In what you do
Creators: name: McFarland, Christian M.
Publisher: name: No Publisher Supplied
Year: 2013

description: This thesis explores the life and music of blues guitarist Freddie King. The Introduction to the thesis chronicles my interest in the music of Freddie King. The first chapter chronicles King’s prolific early career and delineates influences and his musical aesthetic.  The second chapter explains Freddie King’s crossover success in the context of the blues revival movement of the middle 1960s.  The third chapter takes an in depth look at Freddie King’s use of rhythm and metric dissonance with examples from the instrumental tune “Sidetracked,” while chapters four and five are in-depth interviews with a Texas music scholar and notable blues author.
Paranura dalgeri Deharveng 1989
Creators: name: Jantarit, Sopark
name: Bedos, Anne
name: Deharveng, Louis
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Collembola
Neanuridae
Paranura
Paranura dalgeri

description: 52. Paranura dalgeri Deharveng, 1989
Source: Deharveng (1989), Bedos (1994), Rojanavongse et al. (unpublished report). Type deposition: LEITT. Distribution in Thailand. Kanchanaburi (W). Habitat: litter and soil at the entrance of a shaft. Distribution outside Thailand. Only known from Thailand (Amphoe Si Sawat).
description: Published as part of Jantarit, Sopark, Bedos, Anne & Deharveng, Louis, 2016, An annotated checklist of the Collembolan fauna of Thailand, pp. 301-360 in Zootaxa 4169 (2) on page 316, DOI: 10.11646/zootaxa.4169.2.4, http://zenodo.org/record/265801
Jonesin'
Creators: name: Mallory, Dustin E.
Publisher: name: No Publisher Supplied
Year: 2013

description: This thesis explores the life of drummer “Philly” Joseph Rudolf Jones, one of jazz’s most renowned, unknown figures. As the drummer for the Miles Davis Quintet/Sextet and a later incarnation of the Bill Evans Trio, Joe achieved worldwide fame and success. Yet, his life story has always been told in the footnotes of the towering figures he performed with: John Coltrane, Bud Powell, Charlie Parker, Thelonious Monk, etc. Jazz history books recognize Joe’s contributions and nearly all provide a space, albeit a small one, to recognize his accomplishments. Leonard Feather’s The Encyclopedia of Jazz has an entry for Joe, Lewis Porter’s An Historical Survey of Jazz Drumming Styles lists Joe as an important figure in the evolution of jazz drumming, and The Oxford Companion to Jazz states that “just about anyone of consequence worked with Jones.”  These texts and many others put Joe in a place of prominence for a handful of sentences. However, footnoting Joe’s success overlooks the fact that he recorded on more than one-hundred albums from 1955-1960 and was probably the most recorded American drummer in any genre during that time period.    Despite his popularity and critical acclaim, no published author has delved into Joe’s complex life with any depth. This thesis explores Joe’s musical biography and seeks to illuminate the paradoxes therin. Joe’s story contains drug use, prison time, and abrasive behavior. On the other hand, he was an excellent musician and a generous man who mentored many young musicians. Joe’s life is intertwined in a web of circumstantial experiences: a fatherless upbringing, military service during World War II, integrating the Philadelphia Transit Company, and working to survive as a musician in New York. There are also lesser-known parts of his life including his roots as a Rhythm and blues drummer, his love for big band music, and his associations with the avant-garde. Joe overcame the obstacles of socioeconomic status, racism, evolving musical styles, and the drug culture to become a superb musician who still found time to educate the next generation.
Deciding to blow the whistle
Creators: name: Lavena, Cecilia Florencia
Publisher: name: No Publisher Supplied
Year: 2013

description: The act of blowing the whistle on wrongdoing is essential to good government, yet it poses an ethical dilemma to the individual, the organization and society. Using a mixed methods approach, the aim of this dissertation is to examine the individual and organizational factors that facilitate or impede whistleblowing in the US federal government. A logistic regression analysis of survey data collected by the Merit Systems Protection Board, covering 36,926 federal employees from 24 agencies, is employed to examine various individual and organizational factors empirically. In addition, qualitative data from 18 original in-depth interviews with federal whistleblowers were gathered to provide a better understanding of the influences involved in the decision about whether or not to blow the whistle. Findings from the quantitative analysis suggest that, although whistleblowing is a rare event within most federal agencies, its likelihood is positively associated with norm-based and affective work motives, but negatively associated with job satisfaction and several key indicators of organizational culture, including perceptions of respect and openness, cooperativeness and flexibility in the work setting, and fair treatment and trust in the supervisor. The qualitative interview findings revealed similar themes but also suggested additional, more detailed explanations of why public employees blow the whistle in the federal government. Specifically, when asked about the factors associated with their whistleblowing, interviewees frequently mentioned intrinsic individual motives linked to their personal upbringing and values and their commitment to serving the larger public. They also pointed to the existence of a maladapted and unethical work environment that ignored or covered up wrongdoing and threatened to punish whistleblowers. This indicates intrinsic individual motives, particularly those associated with norm-based and affective work motivations, along with perceptions of the existence of an unethical work environment and organizational culture, should be taken into account when developing and sustaining policies to promote ethical behavior and responsible public service in the federal government.
Oral Contraceptives, Hormonal Risk Factors and BRCA1
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: A large number of breast cancers diagnosed at an early age may be due to genetic changes (mutations) in the breast cancer susceptibility gene, BRCA1. Recent evidence suggests however that not all women with one of these mutations will develop breast cancer. It is possible that other genetic or non-genetic factors play a role in whether or when breast cancer occurs in women with a BRCA1 mutation.

 A number of studies have suggested that women who use oral contraceptives at an early age may be at increased risk of breast cancer. There are now a growing number of studies suggesting that use of oral contraceptives may be particularly detrimental in young women with a family history of breast cancer. We have preliminary data suggesting that women with a BRCA1 mutation may have a much higher risk of breast cancer if they have used oral contraceptives than women with no such mutations. However, these findings were based on small numbers, and must be replicated in a larger study.

 We propose to conduct a large study to determine to what extent use of oral contraceptives increases the risk of breast cancer in women with a BRCA1 mutation. We also propose to determine whether reproductive factors and physical exercise influences the risk of breast cancer in women with a BRCA1 mutation, and whether women with a BRCA1 mutation have different mammographic density profiles than women with no such mutations.

 This study will provide valuable information regarding the role of BRCA1 in breast cancer development, and could yield important results in developing intervention regimens and appropriate counseling for women with a BRCA1 mutation.
Additional file 1: of Real-world costs of autosomal dominant polycystic kidney disease in the Nordics
Creators: name: Eriksson, Daniel
name: Karlsson, Linda
name: Eklund, Oskar
name: Dieperink, Hans
name: Honkanen, Eero
name: Melin, Jan
name: Selvig, Kristian
name: Lundberg, Johan
Publisher: name: Figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Marine Biology

description: QR ADPKD CRF 20140331 Final v1.1.pdf – Case report form (CRF) – Questionnaire used to collect data from patients’ medical charts. (PDF 85 kb)
Cerebellum’s role in dual tasking with automaticity of movements
Creators: name: Lau, Victor
Publisher: name: No Publisher Supplied
Year: 2013

description: People perform dual task performances involving cognitive and motor processes. For example, a skilled typist can type while holding a conversation. The cerebellum plays a key role in allowing individuals to perform these kinds of tasks simultaneously. In the performance of these dual tasks, motor movements are “automatic” or trivial to many individuals and thus, do not require explicit attention. Damage to this brain region may impair the performance of automatic motor tasks. Through neuroimaging, researchers were able to show the importance and involvement of the cerebellum in automation during the performance of two concurrent tasks. However, the specific role of the cerebellum in cognition and true mechanism of automation remains a challenge for future investigations.
Paranura globulifer Deharveng 1989
Creators: name: Jantarit, Sopark
name: Bedos, Anne
name: Deharveng, Louis
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Collembola
Neanuridae
Paranura
Paranura globulifer

description: 53. Paranura globulifer Deharveng, 1989
Source: Deharveng (1989), Bedos (1994), Rojanavongse et al. (unpublished report). Type deposition: LEITT. Distribution in Thailand. Phang Nga (P). Habitat: under bark of dead trees at 20 m. altitude. Distribution outside Thailand. Only known from Thailand.
description: Published as part of Jantarit, Sopark, Bedos, Anne & Deharveng, Louis, 2016, An annotated checklist of the Collembolan fauna of Thailand, pp. 301-360 in Zootaxa 4169 (2) on page 316, DOI: 10.11646/zootaxa.4169.2.4, http://zenodo.org/record/265801
Lasconotus Erichson 1845
Creators: name: ALEKSEEV, VITALII
name: MCKELLAR, RYAN C.
name: BUKEJS, ANDRIS
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Zopheridae
Lasconotus

description: Genus Lasconotus Erichson, 1845
Type species: Lasconotus complex LeConte, 1859
Taxonomic assignment. The studied amber specimen shows a combination of characters corresponding to the tribe Synchitini within the subfamily Colydiinae: (1) antennal insertions concealed dorsally; (2) antennae distinctly clubbed, finely and sparsely setose, lacking scale-like setae; (3) all tarsi tetramerous, not dilated; and (4) metacoxae separated by triangular process of abdominal ventrite 1. The new extinct species is placed in the genus Lasconotus based on: antennae 11-segmented with 3-segmented club; supraocular carina strong; finely facetted eyes large; subantennal grooves absent; antennomere 3 longer than antennomere 4; apex of protibia spinose; prosternal process not expanded apically beyond midpoint of procoxa; pronotum with paired sublateral carinae; elytra with distinct carinae; and abdominal ventrite 5 with deep preapical groove.
description: Published as part of ALEKSEEV, VITALII, MCKELLAR, RYAN C. & BUKEJS, ANDRIS, 2024, A revision and addition to Zopheridae (Coleoptera: Tenebrionoidea) in Baltic amber: possible connections between modern Holarctic distributions and Eocene ' amber forests', pp. 201-247 in Zootaxa 5536 (2) on page 213, DOI: 10.11646/zootaxa.5536.2.1, http://zenodo.org/record/14033618
Stuttering burden and psychosocial impact (Engelen et al., 2024)
Creators: name: Engelen, Marscha M.
name: Franken, Marie-Christine J. P.
name: Stipdonk, Lottie W.
name: Horton, Sarah E.
name: Jackson, Victoria E.
name: Reilly, Sheena
name: Morgan, Angela T.
name: Fisher, Simon E.
name: van Dulmen, Sandra
name: Eising, Else
Publisher: name: ASHA journals
Year: 2024
Subjects: classificationCode: 420110
subject: Speech pathology
classificationCode: 460211
subject: Speech production
classificationCode: 420313
subject: Mental health services

description: Purpose: Stuttering is a speech condition that can have a major impact on a person’s quality of life. This descriptive study aimed to identify subgroups of people who stutter (PWS) based on stuttering burden and to investigate differences between these subgroups on psychosocial aspects of life.Method: The study included 618 adult participants who stutter. They completed a detailed survey examining stuttering symptomatology, impact of stuttering on anxiety, education and employment, experience of stuttering, and levels of depression, anxiety, and stress. A two-step cluster analytic procedure was performed to identify subgroups of PWS, based on self-report of stuttering frequency, severity, affect, and anxiety, four measures that together inform about stuttering burden.Results: We identified a high- (n = 230) and a low-burden subgroup (n = 372). The high-burden subgroup reported a significantly higher impact of stuttering on education and employment, and higher levels of general depression, anxiety, stress, and overall impact of stuttering. These participants also reported that they trialed more different stuttering therapies than those with lower burden.Conclusions: Our results emphasize the need to be attentive to the diverse experiences and needs of PWS, rather than treating them as a homogeneous group. Our findings also stress the importance of personalized therapeutic strategies for individuals with stuttering, considering all aspects that could influence their stuttering burden. People with high-burden stuttering might, for example, have a higher need for psychological therapy to reduce stuttering-related anxiety. People with less emotional reactions but severe speech distortions may also have a moderate to high burden, but they may have a higher need for speech techniques to communicate with more ease. Future research should give more insights into the therapeutic needs of people highly burdened by their stuttering.Supplemental Material S1. Identification and description of stuttering subgroups.Supplemental Material S2. Results of sensitivity analysis for age groups.Supplemental Material S3. R code for cluster inspection and principal component analysis.Engelen, M. M., Franken, M.-C. J. P., Stipdonk, L. W., Horton, S. E., Jackson, V. E., Reilly, S., Morgan, A. T., Fisher, S. E., van Dulmen, S., & Eising, E. (2024). The association between stuttering burden and psychosocial aspects of life in adults. Journal of Speech, Language, and Hearing Research, 67(5), 1385–1399. https://doi.org/10.1044/2024_JSLHR-23-00562
N3-type ruthenium rigid rod dyes and N3-type ruthenium bifunctional dyes for studying solar cell properties
Creators: name: Kopecky, Andrew
Publisher: name: No Publisher Supplied
Year: 2013

description: This thesis describes the synthesis and study of two types of ruthenium(II) bipyridyl complexes that were developed to study sensitization processes on TiO2 surfaces.  The thesis will be separated into two parts:  the synthesis, characterization, and study of rigid rod dyes to investigate Voc and recombination, and the synthesis and preliminary results of thiol-substituted dyes that were developed to study the influence of platinum catalysis on redox mediator processes in dye-sensitized solar cells.      Rigid rod dyes, AK0, AK1, and AK2, a series of bis(bipyridyl) bis(thiocyanate) ruthenium(II) dyes (N3-type), were synthesized to study how dye structure affects voltage.  Dyes AK0-2 were synthesized through a one-pot complexation reaction with modified dipyridyl ligands containing 0, 1, or 2 oligo(phenyleneethynylene) bridge units, respectively, to study the effect of the chromophore-semiconductor distance.  The dyes were characterized and their photophysical and photoelectrochemical properties were studied in solution and on TiO2 films.  In DSSCs, the dyes showed an increase in Voc due to decreased charge recombination rates with increasing semiconductor-chromophore distance.  The recombination rate also showed decreased sensitivity to TiO2 electron concentrations as the chromophore-semiconductor distance increased.  A second series of rigid-rod, N3-type dyes, AK3 and AK4, was synthesized through a two-step complexation process proceeding through isolation of a p-cymene ruthenium(II) intermediate. These dyes contained long, saturated alkyl chain (nonyl) substituents on the ancillary bipyridyl ligand, with the goal of increasing solubility and facilitating solution characterization.  These dyes were characterized synthetically and currently are being studied for I2-adduct formation.    The modified thiol dyes were targeted for studying the catalytic process of redox mediator regeneration.  As platinum has been shown to catalyze the I-/I3- redox reaction, it was thought that by incorporating platinum nanoparticles into DSSCs the large overpotential for the I-/I3- redox mediator could be reduced.  A modified N3-type dye was designed with carboxylic acid groups for anchoring to TiO2 in the DSSC on one bipyridyl ligand and thiols on the other for attachment to platinum.  The synthesis of the novel thiolane bipyridyl ligand was followed by a two-step complexation process and both ligand and dye were successfully synthesized and characterized.  The dye, AK6, shows positive current and efficiencies of approximately 3% when used as a sensitizer in an operational DSSC.  It has also been shown to bind to platinum wire.  These preliminary results suggest that this dye may allow for incorporation of platinum nanoparticles into the DSSC, which is currently being investigated.
Negotiating emotional order
Creators: name: Klimek Yingling, Jennifer A.
Publisher: name: No Publisher Supplied
Year: 2013

description: Rationale for the study: Decades of research focusing on treatment and detection of breast cancer has promoted better outcomes in treating the disease and longer survival rates. Despite this there is a significant gap in the literatures regarding the survivorship process. Breast cancer survivorship needs to be fully understood by nurses and health care providers (HCP) in order to obtain optimal health outcomes for this ever growing population. Method: Classic grounded theory was used in this study to explore the process of transitional survivorship from the prospective of women who had completed initial treatment for breast cancer. Approval by the Institutional Board of Research at Rutgers University and Faxton St. Luke’s Healthcare was obtained prior to the commencement of the research. Twelve women were interviewed. All of the women who were interviewed had completed initial treatment for breast cancer, two of the women had recurrence since the initial completion of treatment for breast cancer and one participant had metastatic breast cancer. Interviews were transcribed verbatim and analysis by constant comparison as described by Glaser was employed.  Results: In this study, the basic social process describing how women with breast cancer perceive their illness and take action was negotiating emotional order. Participants were attempting to bring the psychological aspect of having breast cancer into a state of order by negotiating control with cancer, themselves and external factors. From the data a five stages latent process of negotiating emotional order consists of: 1) Losing Life Order, 2) Assisted Life Order, 3) Assuming Life Order 4) Accepting the Things Cannot Control, and 5) Creating Emotional Order. This latent process also had a cyclical property as evidenced by the data collected from participants that had experienced cancer more than once or had a time period where they were being tested for cancer recurrence. Conclusion: This research method provided this population of concern with a voice to assist nurses explore the dynamic challenge women experience once they have completed breast cancer treatment and enter extended survivorship. This study contributed to the literature in several ways and the findings may help healthcare providers who care for breast cancer survivors understand the depth and perpetual emotional impact that breast cancer survivors endure. This study will potentially serve as path for future research and aid in the understanding of the psychological impact that breast cancer has upon survivors.
Control of Estrogen Production in Breast Cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Estrogens have a major effect on the development of breast cancer. About 60% of premenopausal and 75% of postmenopausal breast cancer patients have estrogen-dependent tumors. In estrogen-dependent breast tumors, estrogens induce the production of peptide growth factors which are responsible for the proliferative response of cancer cells. Aromatase is the enzyme that synthesizes estrogens, so an abnormality in the function of aromatase in breast cancer tumors must have a significant influence on tumor growth in breast cancer patients.

 During this grant period, we will design and perform essential experiments to examine the function of aromatase in breast cancer and in surrounding fat cells and develop methods to regulate the function of aromatase in breast cancer patients, including evaluation of the amount of aromatase in breast cancer tumors and in the surrounding fat cells. In addition, experiments are being performed to determine the structural characteristics of aromatase and to provide insight into the interaction between aromatase and its inhibitors.

 We anticipate that this research will have a direct impact on understanding the cause of estrogen-dependent breast cancer and on the prevention of further progression of cancer by controlling the function of aromatase with aromatase inhibitors. This research is relevant to two of the BCRP priority issues for the grant cycle, i.e., Pathogenesis and Prevention of Breast Cancer.
A partnership in the Maghreb
Creators: name: Khoudja, Derek
Publisher: name: No Publisher Supplied
Year: 2013

description: In 1962, Tunisia became the first Arab country to receive Peace Corps volunteers. Traditional scholarship has focused on the Peace Corps as a uniquely American experience; volunteers’ engagement with host country nationals is often reduced to a list of accomplishments and obstacles. Archival documents and volunteer testimony indicates, however, that the relationship between volunteer and host in the Tunisia Program’s first ten years was both fluid and complex. Volunteers did not perform their work in a vacuum and the Peace Corps was far from a one-way experience. Tunisia was a newly post-colonial society and its citizens oftentimes had conflicting visions for their development. Volunteers had to work themselves into Tunisian life, and in doing so, found that they learned as much—if not more—than they had taught.
Breast Cancer Prevention with Phytoestrogens in Grape Juice
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Grape juice has been found to suppress breast cancer cell growth by preventing the synthesis of the female hormone estrogen, which plays a major role in the development of breast cancer. Approximately 60% of premenopausal and 75% of postmenopausal patients have estrogen-dependent tumors. In estrogen-dependent breast tumors, estrogen stimulates the formation of growth factors that are essential for breast cancer growth. In cells, a protein called aromatase produces estrogen, and in breast cancer patients, some tumors contain an abnormally high level of aromatase, which generates a large amount of estrogen. Therefore, an abnormal expression of aromatase in breast is considered to be a risk factor for breast cancer.

 During the previous year, it was found that grape juice stopped the estrogen production in cells in a test tube. Recent experiments using mice demonstrated that the tumors implanted in mice fed with a very small amount of grape juice daily for 5 weeks were one-third the size of those in similarly implanted mice not given grape juice. These results suggest the possibility that drinking grape juice may prevent breast cancer.

 In this study, more extensive animal studies using mice and rats will be performed to critically evaluate these preliminary findings. In addition, experiments will be designed to identify the active components in grape juice that are responsible for the suppression of breast tumor formation. The latter research will provide us with a scientific basis as to why grape juice is capable of suppressing breast tumor formation in mice. Such information could be very important for designing more selective and effective breast cancer prevention strategies given the ready availability of grape juice.
Additional file 1: of The feasibility analysis of omission of elective irradiation to level IB lymph nodes in low-risk nasopharyngeal carcinoma based on the 2013 updated consensus guideline for neck nodal levels
Creators: name: Xiaomin Ou
name: Yibing Miao
name: Xiaoshen Wang
name: Jianhui Ding
name: Xiayun He
name: Chaosu Hu
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Hematology

description: Table S1. Comparison of clinical factors between high-risk and low-risk subgroups. Table S2. Distribution of regional recurrence by risk-stratified subgroups. Table S3. The grades of xerostomia by elective irradiation to level IB. Figure S1. Isodose distribution of submandibular glands. (PDF 240Â kb)
Additional file 1: of The feasibility analysis of omission of elective irradiation to level IB lymph nodes in low-risk nasopharyngeal carcinoma based on the 2013 updated consensus guideline for neck nodal levels
Creators: name: Xiaomin Ou
name: Yibing Miao
name: Xiaoshen Wang
name: Jianhui Ding
name: Xiayun He
name: Chaosu Hu
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Hematology

description: Table S1. Comparison of clinical factors between high-risk and low-risk subgroups. Table S2. Distribution of regional recurrence by risk-stratified subgroups. Table S3. The grades of xerostomia by elective irradiation to level IB. Figure S1. Isodose distribution of submandibular glands. (PDF 237Â kb)