cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Hepatic Histological Findings in Suspected Drug-Induced Liver Injury: Systematic Evaluation and Clinical Associations
Creators: name: Reddy, Rajender
name: Kleiner, David E.
name: Stolz, Andrew
name: Hayashi, Paul H.
name: Chalasani, Naga P.
name: Fontana, Robert J.
name: Navarro, Victor
name: Barnhart, Huiman
name: Lee, William M.
name: Hoofnagle, Jay H.
name: Watkins, Paul B.
name: Talwalkar, Jayant A.
name: Bonkovsky, Herbert L.
name: Davern, Timothy J.
name: Gu, Jiezhun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Drug-induced liver injury (DILI) is considered to be a diagnosis of exclusion. Liver biopsy may contribute to diagnostic accuracy, but the histological features of DILI and their relationship to biochemical parameters and outcomes are not well defined. We have classified the pathological pattern of liver injury and systematically evaluated histological changes in liver biopsies obtained from 249 patients with suspected DILI enrolled in the prospective, observational study conducted by the Drug Induced Liver Injury Network. Histological features were analyzed for their frequency within different clinical phenotypes of liver injury and to identify associations between clinical and laboratory findings and histological features. The most common histological patterns were acute (21%) and chronic hepatitis (14%), acute (9%) and chronic cholestasis (10%), and cholestatic hepatitis (29%). Liver histology from 128 patients presenting with hepatocellular injury had more severe inflammation, necrosis, and apoptosis and more frequently demonstrated lobular disarray, rosette formation, and hemorrhage than those with cholestasis. Conversely, histology of the 73 patients with cholestatic injury more often demonstrated bile plugs and duct paucity. Severe or fatal hepatic injury in 46 patients was associated with higher degrees of necrosis, fibrosis stage, microvesicular steatosis, and ductular reaction among other findings, whereas eosinophils and granulomas were found more often in those with milder injury. Conclusion: We describe an approach for evaluating liver histology in DILI and demonstrate numerous associations between pathological findings and clinical presentations that may serve as a foundation for future studies correlating DILI pathology with its causality and outcome. (Hepatology 2014;59:661–670)
The domain of parabolicity for the Muskat problem
Creators: name: Escher, Joachim
name: Matioc, Bogdan-Vasile
name: Walker, Christoph
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35R37, 35K55, 35Q35

description: We address the well-posedness of the Muskat problem in a periodic geometry and in a setting which allows us to consider general initial and boundary data, gravity effects, as well as surface tension effects. In the absence of surface tension we prove that the Rayleigh-Taylor condition identifies a domain of parabolicity for the Muskat problem. This property is used to establish the well-posedness of the problem. In the presence of surface tension effects the Muskat problem is of parabolic type for general initial and boundary data. As a bi-product of our analysis we obtain that Dirichlet-Neumann type operators associated with certain diffraction problems are negative generators of strongly continuous and analytic semigroups in the scale of small Hölder spaces.
description: 44 pages
Segno e disegno nell’opera di Heinrich Tessenow
Creators: name: Calandra Di Roccolino, Giacomo
Publisher: name: La Rivista di Engramma
Year: 2023
Subjects: Heinrich Tessenow
Baukunstler
Perspective

description: Alongside the completed architectures and writings, Heinrich Tessenow’s drawings are a fundamental part of his work: they are not only tools for arriving at the definition of the project, but are often works that he uses to pursue his research into the art of building. In many cases, these graphic works are the most intimate expression of his being a Baukünstler, understood – in a literal sense – as the perfect synthesis of artist and builder.
Tessenow’s drawings certainly follow the evolution of his architectural language of which they are an expression, but they never change in their different character, at times oriented towards extemporaneous and abstract representation, which could almost be defined as “expressive”, and at times as a tool for design definition and reflection.
IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice
Creators: name: Cappelletti, Monica
name: Softic, Samir
name: Kohli, Rohit
name: Karp, Christopher L.
name: Divanovic, Senad
name: Sartor, R. Balfour
name: Flick, Leah M.
name: Harley, Isaac T.W.
name: Sheridan, Rachel
name: Xanthakos, Stavra A.
name: Stankiewicz, Traci E.
name: Steinbrecher, Kris A.
name: Giles, Daniel A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Inflammation plays a central pathogenic role in the pernicious metabolic and end-organ sequelae of obesity. Among these sequelae, nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in the developed world. The twinned observations that obesity is associated with increased activation of the interleukin (IL)-17 axis and that this axis can regulate liver damage in diverse contexts prompted us to address the role of IL-17RA signaling in the progression of NAFLD. We further examined whether microbe-driven IL-17A regulated NAFLD development and progression. We show here that IL-17RA−/− mice respond to high-fat diet stress with significantly greater weight gain, visceral adiposity, and hepatic steatosis than wild-type controls. However, obesity-driven lipid accumulation was uncoupled from its end-organ consequences in IL-17RA−/− mice, which exhibited decreased steatohepatitis, nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase enzyme expression, and hepatocellular damage. Neutralization of IL-17A significantly reduced obesity-driven hepatocellular damage in wild-type mice. Further, colonization of mice with segmented filamentous bacteria (SFB), a commensal that induces IL-17A production, exacerbated obesity-induced hepatocellular damage. In contrast, SFB depletion protected from obesity-induced hepatocellular damage. Conclusion: These data indicate that obesity-driven activation of the IL-17 axis is central to the development and progression of NAFLD to steatohepatitis and identify the IL-17 pathway as a novel therapeutic target in this condition. (Hepatology 2014;59:1830–1839)
title: Westminster Cathedral Treasury Ms 4: A 15th century spiritual compilation
Creators: name: Cre, Marleen
Publisher: name: University of Glasgow
Year: 1997
Subjects: subject: Art history, Westminster Cathedral. Treasury. Manuscript. 4, Devotional literature, English (Middle), Manuscripts, English (Middle).

description: Westminster Cathedral Treasury Ms 4 is a late fifteenth-early sixteenth century copy of an early-to-mid fifteenth century compilation. The text has a precise and narrow aim : it teaches contemplation - the mystical life - to what must have been an intended audience of some sophistication, using fragments of four religious texts in the vernacular : a Middle English exposition of Psalm 90, Qui Habitat, and a Middle English exposition of psalm 91, Bonum Est (both psalm expositions are sometimes attributed to Walter Hilton), Walter Hilton's Scale of Perfection and the long version of Julian of Norwich's Revelations of Divine Love. The transcript of the compilation provides references to the main editions of the source texts from which the compiler selected the fragments that make up his text. This study aims to show that it is not just the technical putting together of fragments from existing texts that makes a compilation, but rather the thematic unity of the new text that is formed by the selecting and ordering of the fragments. This is why the core of this study is a detailed analysis of the themes of the compilation and the way they have been introduced and elaborated throughout the compilation. In addition to this, this study discusses the compilation's likely intended audience as well as the historical and literary factors that could have led to its composition. The study of individual late medieval spiritual compilations such as Westminster Cathedral Treasury 4 is ultimately aimed at the definition of late medieval spiritual compilations as a genre in their own right, whose characteristics challenge our preconceived notions of authorship and textual integrity.
Theory of strain in single-layer transition metal dichalcogenides
Creators: name: Rostami, Habib
name: Roldán, Rafael
name: Cappelluti, Emmanuele
name: Asgari, Reza
name: Guinea, Francisco
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Strain engineering has emerged as a powerful tool to modify the optical and electronic properties of two-dimensional crystals. Here we perform a systematic study of strained semiconducting transition metal dichalcogenides. The effect of strain is considered within a full Slater-Koster tight-binding model, which provides us with the band structure in the whole Brillouin zone. From this, we derive an effective low-energy model valid around the K point of the BZ, which includes terms up to second order in momentum and strain. For a generic profile of strain, we show that the solutions for this model can be expressed in terms of the harmonic oscillator and double quantum well models, for the valence and conduction bands respectively. We further study the shift of the position of the electron and hole band edges due to uniform strain. Finally, we discuss the importance of spin-strain coupling in these 2D semiconducting materials.
(400706) John L Lyon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Noninvasive in vivo magnetic resonance measures of glutathione synthesis in human and rat liver as an oxidative stress biomarker
Creators: name: Thelwall, Peter E.
name: Smith, Fiona E.
name: Dunn, Michael
name: Skamarauskas, John T.
name: Gamcsik, Michael P.
name: Blain, Peter G.
name: Oakley, Fiona
name: Vidler, Daniel S.
name: Taylor, Roy
name: Bawn, Carlo
name: Clemence, Matthew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Oxidative stress (OS) plays a central role in the progression of liver disease and in damage to liver by toxic xenobiotics. We have developed methods for noninvasive assessment of hepatic OS defenses by measuring flux through the glutathione (GSH) synthesis pathway. 13C-labeled GSH is endogenously produced and detected by in vivo magnetic resonance after administration of [2-13C]-glycine. We report on a successful first-ever human demonstration of this approach as well as preclinical studies demonstrating perturbed GSH metabolism in models of acute and chronic OS. Human studies employed oral administration of [2-13C]-glycine and 13C spectroscopy on a 3T clinical magnetic resonance (MR) imaging scanner and demonstrated detection and quantification of endogenously produced 13C-GSH after labeled glycine ingestion. Plasma analysis demonstrated that glycine 13C fractional enrichment achieved steady state during the 6-hour ingestion period. Mean rate of synthesis of hepatic 13C-labeled GSH was 0.32 ± 0.18 mmole/kg/hour. Preclinical models of acute OS and nonalcoholic steatohepatitis (NASH) comprised CCl4-treated and high-fat, high-carbohydrate diet-fed Sprague-Dawley rats, respectively, using intravenous administration of [2-13C]-glycine and observation of 13C-label metabolism on a 7T preclinical MR system. Preclinical studies demonstrated a 54% elevation of GSH content and a 31% increase in flux through the GSH synthesis pathway at 12 hours after acute insult caused by CCl4 administration, as well as a 23% decrease in GSH content and evidence of early steatohepatitis in the model of NASH. Conclusion: Our data demonstrate in vivo 13C-labeling and detection of GSH as a biomarker of tissue OS defenses, detecting chronic and acute OS insults. The methods are applicable to clinical research studies of hepatic OS in disease states over time as well as monitoring effects of therapeutic interventions.
An Approach toward Artificial Intelligence Alzheimer’s Disease Diagnosis Using Brain Signals
Creators: name: Sadegh-Zadeh, Seyed-Ali
name: Fakhri, Elham
name: Bahrami, Mahboobe
name: Bagheri, Elnaz
name: Khamsehashari, Razieh
name: Noroozian, Maryam
name: Hajiyavand, Amir M.
Publisher: name: Technische Universität Berlin
Year: 2023
Subjects: subject: 610 Medizin und Gesundheit
subject: Alzheimer’s disease
subject: diagnosis
subject: electroencephalogram
subject: machine learning
subject: data augmentation strategy
subject: EEG

description: Background: Electroencephalography (EEG) signal analysis is a rapid, low-cost, and practical method for diagnosing the early stages of dementia, including mild cognitive impairment (MCI) and Alzheimer’s disease (AD). The extraction of appropriate biomarkers to assess a subject’s cognitive impairment has attracted a lot of attention in recent years. The aberrant progression of AD leads to cortical detachment. Due to the interaction of several brain areas, these disconnections may show up as abnormalities in functional connectivity and complicated behaviors. Methods: This work suggests a novel method for differentiating between AD, MCI, and HC in two-class and three-class classifications based on EEG signals. To solve the class imbalance, we employ EEG data augmentation techniques, such as repeating minority classes using variational autoencoders (VAEs), as well as traditional noise-addition methods and hybrid approaches. The power spectrum density (PSD) and temporal data employed in this study’s feature extraction from EEG signals were combined, and a support vector machine (SVM) classifier was used to distinguish between three categories of problems. Results: Insufficient data and unbalanced datasets are two common problems in AD datasets. This study has shown that it is possible to generate comparable data using noise addition and VAE, train the model using these data, and, to some extent, overcome the aforementioned issues with an increase in classification accuracy of 2 to 7%. Conclusion: In this work, using EEG data, we were able to successfully detect three classes: AD, MCI, and HC. In comparison to the pre-augmentation stage, the accuracy gained in the classification of the three classes increased by 3% when the VAE model added additional data. As a result, it is clear how useful EEG data augmentation methods are for classes with smaller sample numbers.
Planning Artificial Light at Night for Pedestrian Visual Diversity in Public Spaces
Creators: name: Radicchi, Antonella
name: Henckel, Dietrich
Publisher: name: Technische Universität Berlin
Year: 2023
Subjects: subject: 333 Boden- und Energiewirtschaft
subject: public spaces
subject: artificial light
subject: night
subject: urban planning
subject: universal design
subject: visual diversity
subject: vision
subject: inclusivity
subject: light walks

description: This article makes the case for addressing pedestrian visual diversity when planning artificial light for public spaces at night, by drawing upon original findings from an exploratory study where twenty-one open-ended interviews were conducted with experts in the fields of artificial lighting, urban planning and health studies. Specifically, this article provides (1) the introduction of the concept of pedestrian visual diversity, defined as the condition, capabilities and needs of visually impaired pedestrians, (2) a systematization of overlooked issues in the planning of artificial light for visual diverse pedestrians in public spaces and (3) the proposition of a participatory framework for the application of lightwalks as an experiential method for involving visual diverse pedestrians in the data collection on and analysis of artificial lighting in public spaces at night. In conclusion, it identifies five strands for further research at the nexus of pedestrian visual diversity, public space and night studies for inclusive light planning.
X-ray-powered macronovae
Creators: name: Kisaka, Shota
name: Ioka, Kunihito
name: Nakar, Ehud
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: A macronova (or kilonova) was observed as an infrared excess several days after short gamma-ray burst, GRB 130603B. Although the $r$-process radioactivity is widely discussed as an energy source, it requires huge mass of ejecta from a neutron star (NS) binary merger. We propose a new model that the X-ray excess gives rise to the simultaneously observed infrared excess via thermal re-emission and explore what constraints this would place on the mass and velocity of the ejecta. This X-ray-powered model explains both the X-ray and infrared excesses with a single energy source by the central engine like a black hole, and allows for broader parameter region, in particular smaller ejecta mass $\sim10^{-3}-10^{-2}M_{\odot}$ with iron mixed as suggested by general relativistic simulations for typical NS-NS mergers, than the previous models. We also discuss the other macronova candidates in GRB 060614 and GRB 080503, and implications for the search of electromagnetic counterparts to gravitational waves.
description: 8 pages, 3 figures. Accepted for publication in Astrophysical Journal
Identification of microRNAs specific for epithelial cell adhesion molecule-positive tumor cells in hepatocellular carcinoma: HEPATOLOGY, Vol. XX, No. X, 2015
Creators: name: Thorgeirsson, Snorri S.
name: Forgues, Marshonna
name: Yamashita, Taro
name: Wang, Xin Wei
name: Khan, Javed
name: Wei, Jun S.
name: Reid, Lola M.
name: Wauthier, Eliane L.
name: Ji, Junfang
name: Zheng, Xin
name: Song, Young
name: Wen, Xinyu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Therapies that target cancer stem cells (CSCs) hold promise in eliminating cancer burden. However, normal stem cells are likely to be targeted due to their similarities to CSCs. It is established that EpCAM is a biomarker for normal hepatic stem cells and EpCAM+AFP+ hepatocellular carcinoma (HCC) cells have enriched hepatic CSCs. We sought to determine if specific miRNAs exist in hepatic CSCs that are not expressed in normal hepatic stem cells. We performed a pair-wised comparison of the miRNA transcriptome of EpCAM+ and corresponding EpCAM− cells isolated from two primary HCC specimens, as well as from two fetal livers and three healthy adult liver donors via small RNA deep sequencing. We found that miR-150, miR-155 and miR-223 were preferentially highly expressed in EpCAM+ HCC cells, which was further validated. Their gene surrogates, identified using miRNA and mRNA profiling in a cohort of 292 HCC patients, were associated with patient prognosis. We further demonstrated that miR-155 was highly expressed in EpCAM+ HCC cells compared to corresponding EpCAM− HCC cells, fetal livers with enriched normal hepatic progenitors, and normal adult livers with enriched mature hepatocytes. Suppressing miR-155 resulted in a decreased EpCAM+ fraction in HCC cells and reduced HCC cell colony formation, migration and invasion in vitro. The reduced levels of identified miR-155 targets predicted the shortened overall survival and time to recurrence of HCC patients. Conclusion: MiR-155 was highly elevated in EpCAM+ HCC cells and might serve as a molecular target to eradicate the EpCAM+ CSC population in human HCCs.
(400703) Flora McFie Lyon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supplementary Materials: Eco-evolutionary dynamics, density-dependent dispersal, and collective behavior: implications for salmon metapopulation robustness
Creators: name: Yeakel, Justin D.
name: Gibert, Jean P.
name: Gross, Thilo
name: Westley, Peter A. H.
name: Moore, Jonathan W.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: 3 Supplementary figures
High-Fidelity 3D Stray Magnetic Field Mapping of Smartphones to Address Safety Considerations with Active Implantable Electronic Medical Devices
Creators: name: Saha, Nandita
name: Millward, Jason M.
name: Herrmann, Carl J. J.
name: Rahimi, Faezeh
name: Han, Haopeng
name: Lacour, Philipp
name: Blaschke, Florian
name: Niendorf, Thoralf
Publisher: name: Technische Universität Berlin
Year: 2023
Subjects: subject: 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten
subject: active implantable medical device
subject: electronic consumer products
subject: electromagnetic interference
subject: stray magnetic field
subject: iPhone 13
subject: COSI Measure
subject: three-axis Hall probe

description: Case reports indicate that magnets in smartphones could be a source of electromagnetic interference (EMI) for active implantable medical devices (AIMD), which could lead to device malfunction, compromising patient safety. Recognizing this challenge, we implemented a high-fidelity 3D magnetic field mapping (spatial resolution 1 mm) setup using a three-axis Hall probe and teslameter, controlled by a robot (COSI Measure). With this setup, we examined the stray magnetic field of an iPhone 13 Pro, iPhone 12, and MagSafe charger to identify sources of magnetic fields for the accurate risk assessment of potential interferences with AIMDs. Our measurements revealed that the stray fields of the annular array of magnets, the wide-angle camera, and the speaker of the smartphones exceeded the 1 mT limit defined by ISO 14117:2019. Our data-driven safety recommendation is that an iPhone 13 Pro should be kept at least 25 mm away from an AIMD to protect it from unwanted EMI interactions. Our study addresses safety concerns due to potential device–device interactions between smartphones and AIMDs and will help to define data-driven safety guidelines. We encourage vendors of electronic consumer products (ECP) to provide information on the magnetic fields of their products and advocate for the inclusion of smartphones in the risk assessment of EMI with AIMDs.
Basic Reproductive ratio from Effects of complexity and seasonality on backward bifurcation in vector–host models.
Creators: name: Bilal, Shakir
name: Michael, Edwin
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences
subject: Computational Biology
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: This file contains information for deriving basic reproduction number
Lineage-dependent effects of aryl hydrocarbon receptor agonists contribute to liver tumorigenesis
Creators: name: Harrill, Joshua A.
name: Parks, Bethany B
name: Rowlands, J. Craig
name: Reid, Lola M.
name: Wauthier, Eliane
name: Thomas, Russell S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Rodent cancer bioassays indicate that the aryl hydrocarbon receptor (AHR) agonist, 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD), causes increases in both hepatocytic and cholangiocytic tumors. Effects of AHR activation have been evaluated on rodent hepatic stem cells (rHpSCs) versus their descendants, hepatoblasts (rHBs), two lineage stages of multipotent, hepatic precursors with overlapping but also distinct phenotypic traits. This was made possible by defining the first successful culture conditions for ex vivo maintenance of rHpScs consisting of a substratum of hyaluronans and Kubota's medium (KM), a serum-free medium designed for endodermal stem/progenitor cells. Supplementation of KM with leukemia inhibitory factor elicited lineage restriction to rHBs. Cultures were treated with various AHR agonists including TCDD, 6-formylindolo-[3,2-b]carbazole (FICZ), and 3-3'-diindolylmethane (DIM) and then analyzed with a combination of immunocytochemistry, gene expression, and high-content image analysis. The AHR agonists increased proliferation of rHpSCs at concentrations producing a persistent AHR activation as indicated by induction of Cyp1a1. By contrast, treatment with TCDD resulted in a rapid loss of viability of rHBs, even though the culture conditions, in the absence of the agonists, were permissive for survival and expansion of rHBs. The effects were not observed with FICZ and at lower concentrations of DIM. Conclusion: Our findings are consistent with a lineage-dependent mode of action for AHR agonists in rodent liver tumorigenesis through selective expansion of rHpSCs in combination with a toxicity-induced loss of viability of rHBs. These lineage-dependent effects correlate with increased frequency of liver tumors. (Hepatology 2015;61:548-560)
An SMLD joint PDF model for turbulent non-premixed combustion using the flamelet progress-variable approach
Creators: name: Coclite, Alessandro
name: Pascazio, Giuseppe
name: De Palma, Pietro
name: Cutrone, Luigi
name: Ihme, Matthias
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: This paper provides an improved flamelet/progress variable (FPV) model for the simulation of turbulent combustion, employing the statistically most likely distribution (SMLD) approach for the joint probability density function (PDF) of the mixture fraction, Z, and of the progress parameter, Λ . Steady-state FPV models are built presuming the func- tional shape of the joint PDF of Z and Λ in order to evaluate Favre-averages of thermody- namic quantities. The mixture fraction is widely assumed to behave as a passive scalar with a mono-modal behaviour modelled by a \b{eta} -distribution. Moreover, under the hypothesis that Z and Λ are statistically independent, the joint PDF coincides with the product of the two marginal PDFs. In this work we discuss these two constitutive hypotheses. The proposed model evaluates the most probable joint distribution of Z and Λ , relaxing some crucial as- sumption on their statistical behaviour. This provides a more general model in the context of FPV approach and an effective tool to verify the adequateness of widely used hypotheses. The model is validated versus experimental data of well-known test cases, namely, the San- dia flames. The results are also compared with those obtained by the standard FPV approach, analysing the role of the PDF functional form on turbulent combustion simulations.
(400705) Annabella [Foulds] Lyon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Army Permit No. SAJ-2017-867 (201700867), Christian Hefner - Seawall Project
titleType: AlternativeTitle
title: Endangered Species Act - Section 7 Consultation Biological Opinion SAJ-2017-00867 (NWP-ACM), Hefner Seawall Installation, Cape Coral, Lee County, Florida
Creators: name: United States. National Marine Fisheries Service. Southeast Region
Publisher: name: United States. National Marine Fisheries Service. Southeast Region
Year: 2017

description: SERO-2017-01839
A Reduced Basis Landweber method for nonlinear inverse problems
Creators: name: Garmatter, Dominik
name: Haasdonk, Bernard
name: Harrach, Bastian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: We consider parameter identification problems in parametrized partial differential equations (PDE). This leads to nonlinear ill-posed inverse problems. One way to solve them are iterative regularization methods, which typically require numerous amounts of forward solutions during the solution process. In this article we consider the nonlinear Landweber method and want to couple it with the reduced basis method as a model order reduction technique in order to reduce the overall computational time. In particular, we consider PDEs with a high-dimensional parameter space, which are known to pose difficulties in the context of reduced basis methods. We present a new method that is able to handle such high-dimensional parameter spaces by combining the nonlinear Landweber method with adaptive online reduced basis updates. It is then applied to the inverse problem of reconstructing the conductivity in the stationary heat equation.
Basic Reproductive ratio from Effects of complexity and seasonality on backward bifurcation in vector–host models
Creators: name: Bilal, Shakir
name: Michael, Edwin
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences
subject: Computational Biology
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: This file contains information for deriving basic reproduction number
ปัจจัยความสำเร็จในการจัดการธุรกิจออนไลน์ในวิถีความปกติใหม่
Creators: name: นันทนา แจ้งสว่าง
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2022
Subjects: ปัจจัยในการจัดการธุรกิจ
ธุรกิจออนไลน์
วิถีความปกติใหม่

description: The Journal of Research and Academics, 5, 5, 279-288
BOSHQA FANLAR NUQTAI NAZARIDAN TEXNOLOGIYA FANINING DOLZARBLIGI
Creators: name: Mukimova, Ziyodaxon
Publisher: name: Zenodo
Year: 2023

description: Texnologiya    hayotimizning    barcha   jabhalarini,    jumladan,    texnologiya tomonidan o'zgartirilgan ta'limni inqilob qildi. Hozirgi zamonda texnologiya ta'limning ajralmas qismiga aylandi va texnologiyaning turli fanlar bilan integratsiyalashuvi yangi imkoniyatlarga  yo'l  ochmoqda.
ปัจจัยที่มีส่งผลต่อความวิตกกังวลในการเรียนสาขาวิชาการบริหารการศึกษา ของนักศึกษามหาวิทยาลัยราชภัฏนครสวรรค์
Creators: name: ฐิตินันท์ ด้วงสุวรรณ
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2022
Subjects: ปัจจัยที่ส่งผลต่อความวิตกกังวลในการเรียน
สาขาบริหารการศึกษา
มหาวิทยาลัยราชภัฏนครสวรรค์

description: The Journal of Research and Academics, 5, 5, 289-302
Supplementary Material - Details on Methods and Data from Uncertain impacts on economic growth when stabilizing global temperatures at 1.5°C or 2°C warming.
Creators: name: Pretis, Felix
name: Schwarz, Moritz
name: Tang, Kevin
name: Haustein, Karsten
name: Allen, Myles R.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Statistics
subject: FOS: Mathematics
subject: 19999 Mathematical Sciences not elsewhere classified

description: Empirical evidence suggests that variations in climate affect economic growth across countries over time. However, little is known about the relative impacts of climate change on economic outcomes when global mean surface temperature (GMST) is stabilized at 1.5°C or 2°C warming relative to pre-industrial levels. Here we use a new set of climate simulations under 1.5°C and 2°C warming from the ‘Half a degree Additional warming, Prognosis and Projected Impacts' (HAPPI) project to assess changes in economic growth using empirical estimates of climate impacts in a global panel dataset. Panel estimation results that are robust to outliers and breaks suggest that within-year variability of monthly temperatures and precipitation has little effect on economic growth beyond global nonlinear temperature effects. While expected temperature changes under a GMST increase of 1.5°C lead to proportionally higher warming in the Northern Hemisphere, the projected impact on economic growth is larger in the Tropics and Southern Hemisphere. Accounting for econometric estimation and climate uncertainty, the projected impacts on economic growth of 1.5°C warming are close to indistinguishable from current climate conditions, while 2°C warming suggests statistically lower economic growth for a large set of countries (median projected annual growth up to 2% lower). Level projections of gross domestic product (GDP) per capita exhibit high uncertainties with median projected global average GDP per capita approximately 5% lower at the end of the century under 2°C warming relative to 1.5°C. The correlation between climate-induced reductions in per capita GDP growth and national income levels is significant at the p
The organization of AMPA receptor subunits at the postsynaptic membrane: AMPARs IN CA1
Creators: name: Jacob, Amanda L.
name: Weinberg, Richard J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: AMPA receptors are the principal mediators of excitatory synaptic transmission in the mammalian central nervous system. The subunit composition of these tetrameric receptors helps to define their functional properties, and may also influence the synaptic trafficking implicated in long-term synaptic plasticity. However, the organization of AMPAR subunits within the synapse remains unclear. Here, we use postembedding immunogold electron microscopy to study the synaptic organization of AMPAR subunits in stratum radiatum of CA1 hippocampus in the adult rat. We find that GluA1 concentrates away from the center of the synapse, extending at least 25 nm beyond the synaptic specialization; in contrast, GluA3 is uniformly distributed along the synapse, and seldom extends beyond its lateral border. The fraction of extrasynaptic GluA1 is markedly higher in small than in large synapses; no such effect is seen for GluA3. These observations imply that different kinds of AMPARs are differently trafficked to and/or anchored at the synapse.
title: Army Permit No. SAJ-2017-1496 (201701496), Ross Coviello - Seawall Project
titleType: AlternativeTitle
title: Endangered Species Act - Section 7 Consultation Biological Opinion SAJ-2017-0 1496 (NWP-DSD), Coviello Seawall Installation, Cape Coral, Lee County, Florida
Creators: name: United States. National Marine Fisheries Service. Southeast Region
Publisher: name: United States. National Marine Fisheries Service. Southeast Region
Year: 2017

description: SERO-2017-01838
Tracce visive di pensiero. Presentazione di Peter Märkli Dessins/Disegni
Creators: name: Maguolo, Michela
Publisher: name: La Rivista di Engramma
Year: 2023
Subjects: Peter Markli
Drawing
Architectural drawing

description: Peter Märkli: Dessins/ Disegni (Caryatide, Paris 2023) edited by Fabio Don and Claudia Mion is a collection of 330 drawings by Swiss architect Peter Märkli, with essays by Erich Brändle, Kenjiro Hosaka, Erwin Viray, Elizabeth Hatz, Irina Davidovici, Alexander Brodsky, Kiril Ass, Florian Beigel, Philipp Christou and Mariabruna Fabrizi. The article reviews the book, highlighting the value of visible traces of thought that Märkli’s drawings represent, and the endless searching for form in its innumerable variations that characterises Märkli’s work.
title: Army Permit No. SAJ-2017-2427 (201702427), Honc Marine Contracting, Inc. - Nawarra Seawall Project
titleType: AlternativeTitle
title: Endangered Species Act - Section 7 Consultation Biological Opinion SAJ-2017-02427 (NW-BAL), Hone Marine Contracting, Inc., on behalf of Christiane Nawarra, Shoreline Stabilization, Cape Coral, Lee County, Florida
Creators: name: United States. National Marine Fisheries Service. Southeast Region
Publisher: name: United States. National Marine Fisheries Service. Southeast Region
Year: 2017

description: SERO-2017-01837
A Thesis Submitted to the School of Graduate studies of Addis Ababa University in Partial Fulfillment of the Requirements for the Degree of Master in Executive Business Administration.
Creators: name: Mulugeta, Rahel
Publisher: name: Zenodo
Year: 2015

description: This thesis aims to examine implementation of E-banking in Ethiopian banking industry with

respect to the barriers which can influence firms from taking advantage of E-banking system and

expected benefits derived by adopting the system. The study was conducted based on the data

gathered from seventeen banks in Ethiopia; sixteen private banks and one state owned bank.

Descriptive research approach was used to answer the research questions that emerge through the

review of existing literature and responses from participants through questionnaire. The study

statistically analyzes data obtained from the survey questionnaire. A research framework is

developed based on technology-organization-environment (TOE) framework to guide the study.

The result of the study indicated that, the major barriers Ethiopian banking industry faces in the

implementation of E-banking are technology infrastructure being not easily available and low

level of telecommunication network, lack of participation of employees in the implementation

process, lack of training, absence of management support, lack of government support and

absence of legal framework. The study also revealed direct and indirect benefits from E-banking

implementation which are low cost in performing transaction, high speed and efficiency in

service delivery, increased productivity and profitability of banks and improvement in customer

service. The study suggests a series of measures which could be taken by the banking industry

and by government to address various challenges identified in the thesis. These measures

include: government support in providing technology infrastructure for ICT development and

setting the necessary legal framework, banks to modernize their service by mobilizing all their

resources through participating their staffs and providing trainings, and banks to create

awareness to customers on how to make use of E-banking products and the benefits that will

come out of it.

V
Quantum-mechanical machinery for rational decision-making in classical guessing game
Creators: name: Bang, Jeongho
name: Ryu, Junghee
name: Pawłowski, Marcin
name: Ham, B. S.
name: Lee, Jinhyoung
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In quantum game theory, one of the most intriguing and important questions is, "Is it possible to get quantum advantages without any modification of the classical game?" The answer to this question so far has largely been negative. So far, it has usually been thought that a change of the classical game setting appears to be unavoidable for getting the quantum advantages. However, we give an affirmative answer here, focusing on the decision-making process (we call 'reasoning') to generate the best strategy, which may occur internally, e.g., in the player's brain. To show this, we consider a classical guessing game. We then define a one-player reasoning problem in the context of the decision-making theory, where the machinery processes are designed to simulate classical and quantum reasoning. In such settings, we present a scenario where a rational player is able to make better use of his/her weak preferences due to quantum reasoning, without any altering or resetting of the classically defined game. We also argue in further analysis that the quantum reasoning may make the player fail, and even make the situation worse, due to any inappropriate preferences.
description: 9 pages, 10 figures, The scenario is more improved
Acculturative Stress Among Documented and Undocumented Latino Immigrants in the United States
Creators: name: Rodriguez, Nestor
name: Arbona, Consuelo
name: Wiesner, Margit
name: Olvera, Norma
name: Linares, Adriana
name: Hagan, Jacqueline
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The purpose of the study was to examine differences between documented and undocumented Latino immigrants in the prevalence of three immigration-related challenges (separation from family, traditionality, and language difficulties), which were made more severe after the passage of restrictive immigration legislation in 1996. Specifically, the study sought to determine the combined and unique associations of legal status, the three immigration-related challenges listed above, and fear of deportation to acculturative stress related to family and other social contexts. Participants in the study consisted of 416 documented and undocumented Mexican and Central American immigrants living in two major cities in Texas. The Hispanic Stress Inventory–Immigrant form was used to assess acculturative stress in the sample. Results indicated that although undocumented immigrants reported higher levels of the immigration challenges of separation from family, traditionality, and language difficulties than documented immigrants, both groups reported similar levels of fear of deportation. Results also indicated that the immigration challenges and undocumented status were uniquely associated with extrafamilial acculturative stress but not with intrafamilial acculturative stress. Only fear of deportation emerged as a unique predictor of both extrafamililal and intrafamilial acculturative stress.
title: Reinitiation of Tappan Zee Bridge Replacement (Reinitiation of January 4, 2017 Opinion)
titleType: AlternativeTitle
title: Endangered Species Act - Section 7 Consultation Biological Opinion Tappan Zee Bridge Replacement NER-2017-14375
Creators: name: United States. National Marine Fisheries Service. Greater Atlantic Regional Fisheries Office
Publisher: name: United States. National Marine Fisheries Service. Greater Atlantic Regional Fisheries Office
Year: 2017

description: GARFO-2017-01421
title: Facility Improvements (NWS-2017-431, J.E. McAmis, Inc)
titleType: AlternativeTitle
title: Endangered Species Act Section 7(a)(2) Biological Opinion and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Response the J.E. McAmis, Inc. Open-Cell Bulkhead Construction, Old Mouth of the Cowlitz River, Longview, Washington (HUC 17080030700) (NWS-2017-431)
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2023

description: WCRO-2022-00807
title: Army Permit No. SAJ-2017-2487 (201702487), Danielle Von Behren - Seawall Project
titleType: AlternativeTitle
title: Endangered Species Act - Section 7 Consultation Biological Opinion SAJ-2017-02487 (NW-SJR), Jennifer Chilson on behalf of Danielle Von Behren, Shoreline Stabilization, Cape Coral, Lee County, Florida
Creators: name: United States. National Marine Fisheries Service. Southeast Region
Publisher: name: United States. National Marine Fisheries Service. Southeast Region
Year: 2017

description: SERO-2017-01836
(400698) Emmanuel Tombazis
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Концепция бережливого производства в реализации индивидуальных траекторий обучения
title: The Concept of Lean Production in Implementing Individual Learning Trajectories
Creators: name: Грошев, Александр Романович
Publisher: name: Издательский центр СурГУ
Year: 2022

description: Представлены проблемы реализации индивидуальных траекторий обучения в профессиональном образовании, приведено описание модели индивидуально-ориентированного обучения. Рассмотрены возможности применения концепции «Бережливое производство» в образовательных процессах высшего образования с учетом основных видов потерь университета при оказании образовательных услуг; проанализированы их причины, а также направления перестройки производственного процесса при переходе образования на индивидуально-ориентированное обучение; исследована возможность и необходимость реализации модели в Сургутском государственном университете.
description: The article discusses issues of implementing individual learning trajectories in professional education. A model of individually oriented education is described. The possibilities to apply the concept of lean production in educational system of higher education are analyzed, considering the main losses of a university when providing educational services. Reasons causing these losses and paths for restructuring of production process when transitioning towards the individually oriented education are analyzed. The possibility and necessity of implementing the model in educational process of Surgut State University are studied.
Recent Progress in the thermodynamics of ferrotoroidic materials
Creators: name: Planes, Antoni
name: Castan, Teresa
name: Saxena, Avadh
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Recent theoretical and experimental progress on the study of ferrotoroidic materials is reviewed. The basic field equations are first described and then the expressions for magnetic toroidal moment and toroidization are derived. Relevant materials and experimental observation of magnetic toroidal moment and toroidal domains are summarized next. The thermodynamics of such magnetic materials is discussed in detail with examples of ferrorotoidic phase transition studied using Landau modelling. Specifically, an example of application of Landau modelling to the study of toroidocaloric effect is also provided. Recent results of polar nanostructures with electrical toroidal moment are finally reviewed.
description: 23 pages, 5 figures