cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Balanced factorisations
Creators: name: Klyachko, Anton A.
name: Vassilyev, Anton N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Rings and Algebras (math.RA)
subject: Commutative Algebra (math.AC)
subject: History and Overview (math.HO)
subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: Any rational number can be factored into a product of several rationals whose sum vanishes. This simple but nontrivial fact was suggested as a problem on a maths olympiad for high-school students. We completely solve similar questions in all finite fields and in some other rings, e.g., in the complex and real matrix algebras. Also, we state several open questions.
description: 7 pages. A Russian version of this paper is at http://halgebra.math.msu.su/staff/klyachko/papers.htm
ETV6-NTRK3 Fusion Oncogene Initiates Breast Cancer from Committed Mammary Progenitors via Activation of AP1 Complex
Creators: name: Hock, Hanno
name: Perou, Charles M.
name: Sorensen, Poul H.
name: Godinho, Frank J.
name: Kim, Seong Jin
name: Lannon, Chris L.
name: Li, Zhe
name: Tognon, Cristina E.
name: Cho, Eunah
name: Bronson, Roderick T.
name: Orkin, Stuart H.
name: Yasaitis, Laura
name: Herschkowitz, Jason I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: To better understand the cellular origin of breast cancer, we developed a mouse model that recapitulates expression of the ETV6-NTRK3 (EN) fusion oncoprotein, the product of the t(12;15)(p13;q25) translocation characteristic of human secretory breast carcinoma. Activation of EN expression in mammary tissues by Wap-Cre leads to fully penetrant, multifocal malignant breast cancer with short latency. We provide genetic evidence that in nulliparous Wap-Cre;EN females, committed alveolar bipotent or CD61+ luminal progenitors, are targets of tumorigenesis. Furthermore, EN transforms these otherwise transient progenitors through activation of the AP1 complex. Given increasing relevance of chromosomal translocations in epithelial cancers, such mice serve as a paradigm for the study of their genetic pathogenesis and cellular origins, and generation of novel preclinical models.
XALQ TA'LIMI TIZIMIDA PERSONAL MENEJMENT VA UNI TAKOMILLASHTIRISH
Creators: name: Zarpullayeva, Kamola
Publisher: name: Zenodo
Year: 2023

description: Maqolada Xalq ta'limi tizimida personal menejmentni shakllantirish kadrlar siyosatidagi muammolar hamda ularni takomillashtirish masalalari keltirib o'tilgan.
SUPPLEMENTARY MATERIAL; Cytochrome B Haplotypes; D-loop Haplotypes from Phylogenetic evidence for the ancient Himalayan wolf: towards a clarification of their taxonomic status based on genetic sampling from western Nepal.
Creators: name: Werhahn, Geraldine
name: Senn, Helen
name: Kaden, Jennifer
name: Joshi, Jyoti
name: Bhattarai, Susmita
name: Kusi, Naresh
name: Sillero-Zubiri, Claudio
name: Macdonald, David W.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 60301 Animal Systematics and Taxonomy
subject: 60310 Plant Systematics and Taxonomy

description: The supplementary material contains details on the genetic analysis procedure, tables with details on genetic sequences used in the analyses, and additional phylogenies built with Neighbourhood-joining; This file contains the two unique Cytochrome b haplotypes for Himalayan wolf and the one unque haplotype for domestic dog found in Humla Nepal.; This file contains the three unique D-loop haplotypes for Himalayan wolf and the one unique haplotype for domestic dog found in Humla Nepal. It also contains two Grey wolf haplotypes found in scats from Mongolia that were in the authors collection.
Validation of observations obtained with a liquid mirror telescope by comparison with Sloan Digital Sky Survey observations
Creators: name: Borra, E. F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The results of a search for peculiar astronomical objects using very low resolution spectra obtained with the NASA Orbital Debris Observatory (NODO) 3 meter diameter liquid mirror telescope (LMT) are compared with results of spectra obtained with the Sloan Digital Sky Survey (SDSS). The main purpose of this comparison is to verify whether observations taken with this novel type of telescope are reliable. This comparison is important because LMTs are a novel type of inexpensive telescope that are very useful for astronomical surveys, particularly surveys in the time domain, and a validation of data taken with an LMT, by comparison with data from a classical telescope, will validate their reliability. We start from a published data analysis that classified only 206 of the 18,000 astronomical objects observed with the NODO liquid mirror telescope as peculiar. A total of 29 of these 206 objects were found in the SDSS. The reliability of the NODO data can be seen by the results of the detailed analysis that, in practice, less than 0.3% of the 18,000 spectra were incorrectly identified as peculiar objects, most probably because they are variable stars. We conclude that the liquid mirror telescope gave reliable observations, comparable to those that would have been obtained with a telescope using a glass mirror.
description: Accepted for publication in the Astronomical Journal
title: Radiology of Diplopia – “Double trouble”
Creators: name: Ilangovan, Gurubharath
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Eyes
subject: CT
subject: MR
subject: Diagnostic procedure
subject: Aneurysms

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Binocular diplopia may be caused by life-threatening causes requiring careful neuro-imaging in patients who have new progressive symptoms, more than one symptom, or history of neoplasm. An awareness of the radiographic anatomy of cranial nerves III,...
Speed of sound data, derived perfect-gas heat capacities, and acoustic virial coefficients of a calibration standard natural gas mixture and a low-calorific $H_{2}$-enriched mixture
Creators: name: Lozano-Martín, Daniel
name: Vega-Maza, David
name: Moreau, Alejandro
name: Martín, M. Carmen
name: Tuma, Dirk
name: Segovia, José J.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: This work aims to address the technical aspects related to the thermodynamic characterization of natural gas mixtures blended with hydrogen for the introduction of alternative energy sources within the Power-to-Gas framework. For that purpose, new experimental speed of sound data are presented in the pressure range between (0.1 up to 13) MPa and at temperatures of (260, 273.16, 300, 325, and 350) K for two mixtures qualified as primary calibration standards: a 11 component synthetic natural gas mixture (11 M), and another low-calorific $H_{2}$-enriched natural gas mixture with a nominal molar percentage $x_{H_{2}}$ = 3%. Measurements have been gathered using a spherical acoustic resonator with an experimental expanded ($k$ = 2) uncertainty better than 200 parts in $10^{6}$ (0.02%) in the speed of sound. The heat capacity ratio as perfect-gas $γ_{pg}$, the molar heat capacity as perfect-gas $C_{p,m}^{pg}$, and the second $β_{a}$ and third $γ_{a}$ acoustic virial coefficients are derived from the speed of sound values. All the results are compared with the reference mixture models for natural gas-like mixtures, the AGA8-DC92 EoS and the GERG-2008 EoS, with special attention to the impact of hydrogen on those properties. Data are found to be mostly consistent within the model uncertainty in the 11 M synthetic mixture as expected, but for the hydrogen-enriched mixture in the limit of the model uncertainty at the highest measuring pressures.
(401893) James Lorimer
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Joins and bones complication after active covid-19 infection
Creators: name: Sieron, Dominik
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Musculoskeletal bone
subject: MR
subject: Diagnostic procedure
subject: Embolism / Thrombosis

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: The coronavirus 2 (SARS-CoV-2) (COVID-19) pandemic has stimulated an unprecedented response by the global scientific community to better understand the disease. However, many questions about SARS-CoV-2 remain unanswered. Various hypotheses have been...
SUPPLEMENTARY MATERIAL; Cytochrome B Haplotypes; D-loop Haplotypes from Phylogenetic evidence for the ancient Himalayan wolf: towards a clarification of their taxonomic status based on genetic sampling from western Nepal
Creators: name: Werhahn, Geraldine
name: Senn, Helen
name: Kaden, Jennifer
name: Joshi, Jyoti
name: Bhattarai, Susmita
name: Kusi, Naresh
name: Sillero-Zubiri, Claudio
name: Macdonald, David W.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 60301 Animal Systematics and Taxonomy
subject: 60310 Plant Systematics and Taxonomy

description: The supplementary material contains details on the genetic analysis procedure, tables with details on genetic sequences used in the analyses, and additional phylogenies built with Neighbourhood-joining; This file contains the two unique Cytochrome b haplotypes for Himalayan wolf and the one unque haplotype for domestic dog found in Humla Nepal.; This file contains the three unique D-loop haplotypes for Himalayan wolf and the one unique haplotype for domestic dog found in Humla Nepal. It also contains two Grey wolf haplotypes found in scats from Mongolia that were in the authors collection.
An excited-state approach within full configuration interaction quantum Monte Carlo
Creators: name: Blunt, N. S.
name: Smart, Simon D.
name: Booth, George H.
name: Alavi, Ali
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present a new approach to calculate excited states with the full configuration interaction quantum Monte Carlo (FCIQMC) method. The approach uses a Gram-Schmidt procedure, instantaneously applied to the stochastically evolving distributions of walkers, to orthogonalize higher energy states against lower energy ones. It can thus be used to study several of the lowest-energy states of a system within the same symmetry. This additional step is particularly simple and computationally inexpensive, requiring only a small change to the underlying FCIQMC algorithm. No trial wave functions or partitioning of the space is needed. The approach should allow excited states to be studied for systems similar to those accessible to the ground-state method, due to a comparable computational cost. As a first application we consider the carbon dimer in basis sets up to quadruple-zeta quality, and compare to existing results where available.
description: 10 pages, 7 figures
Volunteerism, solidarity and social capital
Creators: name: Valastro, Alessio
Publisher: name: QuiEdit
Year: 2015
Subjects: volunteerism; social capital; individualism

description: This paper focuses on volunteerism, which has been increasingly acknowledged and appreciated in Italy over the last years as a significant expression of solidarity and participation and a promoter of human rights. As Ota De Leonardis puts it, this phenomenon is «blurred, with uncertain boundaries and extremely diversified». (De Leonardis, 1998: 53) The paper, written in the European Year of Volunteering, aims at analyzing the collective system of volunteering with a view to assessing the phenomenon inItaly, as well as its evolutionary dynamics, which have been profoundly affected by the entry into force of the framework law on volunteering in 1991. It is important to underline the public importance of such actions, above all in the perspective of the link between volunteering and social capital. These concept will be analyzed within the framework of some analytical approaches to the concept of social capital in the literature.
description: Italian Sociological Review, Vol 2, No 1 (2012)
title: Multimodality imaging in the differential diagnosis of true versus false left ventricle aneurysm: Hints and pitfalls
Creators: name: Berecova, Zuzana
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Cardiac
subject: CT-Angiography
subject: Digital radiography
subject: MR
subject: Diagnostic procedure
subject: Aneurysms

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To define the etiology, formation, and morphology of true and false left ventricle aneurysm (LVA). To review signs and refer to hints and pitfalls in the true and false LVA imaging with different radiology...
In Vivo-Restricted and Reversible Malignancy Induced by Human Herpesvirus-8 KSHV: A Cell and Animal Model of Virally Induced Kaposi's Sarcoma
Creators: name: Chiozzini, Chiara
name: Vincent, Loïc
name: Rafii, Shahin
name: Hilsher, Chelsey
name: Dittmer, Dirk P.
name: Duran, Elda M.
name: Cavallin, Lucas E.
name: Mesri, Enrique A.
name: La Perle, Krista M.D.
name: Eroles, Pilar
name: Hooper, Andrea T.
name: Gao, Shou Jiang
name: Asgari, Zahra
name: Mutlu, Agata D.Agostino
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Transfection of a Kaposi's sarcoma (KS) herpesvirus (KSHV) Bacterial Artificial Chromosome (KSHVBac36) into mouse bone marrow endothelial lineage cells generates a cell (mECK36) that forms KS-like tumors in mice. mECK36 expressed most KSHV genes and were angiogenic, but didn't form colonies in soft agar. In nude mice, mECK36 formed KSHV-harboring vascularized spindle-cell sarcomas that were LANA+/podoplanin+, overexpressed VEGF and Angiopoietin ligands and receptors, and displayed KSHV and host transcriptomes reminiscent of KS. mECK36 that lost the KSHV episome reverted to non-tumorigenicity. siRNA suppression of KSHV vGPCR, an angiogenic gene up-regulated in mECK36 tumors, inhibited angiogenicity and tumorigenicity. These results show that KSHV malignancy is in vivo growth-restricted and reversible, defining mECK36 as a biologically sensitive animal model of KSHV-dependent KS.
Velocity-resolved [CII] emission and [CII]/FIR Mapping along Orion with Herschel
Creators: name: Goicoechea, J. R.
name: Teyssier, D.
name: Etxaluze, M.
name: Goldsmith, P. F.
name: Ossenkopf, V.
name: Gerin, M.
name: Bergin, E. A.
name: Black, J. H.
name: Cernicharo, J.
name: Cuadrado, S.
name: Encrenaz, P.
name: Falgarone, E.
name: Fuente, A.
name: Hacar, A.
name: Lis, D. C.
name: Marcelino, N.
name: Melnick, G. J.
name: Muller, H. S. P.
name: Persson, C.
name: Pety, J.
name: Rollig, M.
name: Schilke, P.
name: Simon, R.
name: Snell, R. L.
name: Stutzki, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the first 7.5'x11.5' velocity-resolved map of the [CII]158um line toward the Orion molecular cloud-1 (OMC-1) taken with the Herschel/HIFI instrument. In combination with far-infrared (FIR) photometric images and velocity-resolved maps of the H41alpha hydrogen recombination and CO J=2-1 lines, this data set provides an unprecedented view of the intricate small-scale kinematics of the ionized/PDR/molecular gas interfaces and of the radiative feedback from massive stars. The main contribution to the [CII] luminosity (~85%) is from the extended, FUV-illuminated face of the cloud G_0>500, n_H>5x10^3 cm^-3) and from dense PDRs (G_0~10^4, n_H~10^5 cm^-3) at the interface between OMC-1 and the HII region surrounding the Trapezium cluster. Around 15% of the [CII] emission arises from a different gas component without CO counterpart. The [CII] excitation, PDR gas turbulence, line opacity (from [13CII]) and role of the geometry of the illuminating stars with respect to the cloud are investigated. We construct maps of the [CII]/FIR and FIR/M_Gas ratios and show that [CII]/FIR decreases from the extended cloud component (10^-2-10^-3) to the more opaque star-forming cores (10^-3-10^-4). The lowest values are reminiscent of the "[CII] deficit" seen in local ultra-luminous IR galaxies hosting vigorous star formation. Spatial correlation analysis shows that the decreasing [CII]/FIR ratio correlates better with the column density of dust through the molecular cloud than with FIR/M_Gas. We conclude that the [CII] emitting column relative to the total dust column along each line of sight is responsible for the observed [CII]/FIR variations through the cloud.
description: 21 pages, 17 figures. Accepted for publication in the Astrophysical Journal (2015 August 12). Figures 2, 6 and 7 are bitmapped to lower resolution. This is version 2 after minor editorial changes. Notes added after proofs included
title: A pragmatic analysis of the predictive values of D-dimer in the diagnosis of acute pulmonary thromboembolism using CT Pulmonary Angiogram (CTPA).
Creators: name: Santana, Ernesto
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Pulmonary vessels
subject: CT-Angiography
subject: Laboratory tests
subject: Embolism / Thrombosis

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: To analyze the predictive utility of different cut-off values of D-dimer in the diagnosis of pulmonary embolism (PE) using...
(401888) David Webster
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supplementary tables and figures from No evidence for extrinsic post-zygotic isolation in a wild Saccharomyces yeast system.
Creators: name: Charron, Guillaume
name: Landry, Christian R.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: supplementary figures and tables supporting the results
Thick Braneworlds and the Gibbons-Kallosh-Linde No-go Theorem in the Gauss-Bonnet Framework
Creators: name: Dias, M.
name: da Silva, J. M. Hoff
name: da Rocha, Roldao
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The sum rules related to thick braneworlds are constructed, in order to encompass Gauss-Bonnet terms. The generation of thick branes is hence proposed in a periodic extra dimension scenario, what circumvents the Gibbons-Kallosh-Linde no-go theorem in this context.
description: 6 pages, to appear in the EPL. arXiv admin note: text overlap with arXiv:1406.6324
Tuning the bulk properties of bidisperse granular mixtures by small amount of fines
Creators: name: Kumar, Nishant
name: Magnanimo, Vanessa
name: Ramaioli, Marco
name: Luding, Stefan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the bulk properties of isotropic bidisperse granular mixtures using discrete element simulations. The focus is on the influence of the size (radius) ratio of the two constituents and volume fraction on the mixture properties. We show that the effective bulk modulus of a dense granular (base) assembly can be enhanced by up to 20% by substituting as little as 5% of its volume with smaller sized particles. Particles of similar sizes barely affect the macroscopic properties of the mixture. On the other extreme, when a huge number of fine particles are included, most of them lie in the voids of the base material, acting as rattlers, leading to an overall weakening effect. In between the limits, an optimum size ratio that maximizes the bulk modulus of the mixture is found. For loose systems, the bulk modulus decreases monotonically with addition of fines regardless of the size ratio. Finally, we relate the mixture properties to the 'typical' pore size in a disordered structure as induced by the combined effect of operating volume fraction (consolidation) and size ratio.
(401890) David Kidd
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Sportunterricht in Sprachlernklassen - Der Stellenwert von Bewegung für geflüchtete Kinder und ihren Spracherwerb
Creators: name: Rackemann, Julius Bo
Publisher: name: Hannover : Gottfried Wilhelm Leibniz Universität Hannover
Year: 2016
Subjects: subject: Zweitsprache
subject: Deutsch
subject: Schule
subject: Sport
subject: Bewegung
subject: Spracherwerb
subject: Sprachlernklasse
subject: Sprachförderung
subject: Sportwissenschaft
subject: Linguistik
subject: Didaktik
subject: Fremdsprachenlernen
subject: Sport
subject: Bewegung
subject: Dewey Decimal Classification::400 | Sprache, Linguistik
subject: Dewey Decimal Classification::700 | Künste, Bildende Kunst allgemein::790 | Freizeitgestaltung, Darstellende Kunst

description: Sprachförderung für Flüchtlinge im Sportunterricht anzubahnen, ist ein notwendiger und lohnender Bestandteil von adressatengerechtem Sportunterricht. Über eine Einordnung der Lebenssituation geflüchteter Kinder in Deutschland erfolgt eine Herleitung der Legitimationsebenen von Sport und Bewegung. Neben diesem Aspekt ist vor allem der Spracherwerb (Deutsch als Zweitsprache) ein bedeutungsvoller Faktor zur Steigerung des Wohlbefindens und der Handlungsfähigkeit in der Aufnahmegesellschaft. Die Verbindung beider Ebenen ist erklärtes Ziel eines sich anpassenden und weiterentwicklenden Sportunterrichts für diese Zielgruppe. Im und durch Sportunterricht sind Verbesserungen der sprachlichen Kompetenzen erreichbar. Eine Zusammenstellung von Qualitätsmerkmalen einer Spracherwerbsunterstützung im Sportunterricht stellt die wichtige Basis für den angeschlossenen Vergleich zweier Beschulungssysteme dar: 1. Sportunterricht im Rahmen der Sprachlernklasse und 2. Sportunterricht in den Zielklassen.
HIF-α Effects on c-Myc Distinguish Two Subtypes of Sporadic VHL-Deficient Clear Cell Renal Carcinoma
Creators: name: Flaherty, Keith T.
name: Greenberg, Roger A.
name: Oquendo, C. Elisa
name: Simon, M. Celeste
name: Letrero, Richard
name: Nathanson, Katherine L.
name: Dondeti, Vijay R.
name: Gordan, John D.
name: Lal, Priti
name: Parekh, Krishna N.
name: Rathmell, W. Kimryn
name: Keith, Brian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: VHL tumor suppressor loss results in hypoxia inducible factor-alpha (HIF-α) stabilization, and occurs in 70% of sporadic clear cell renal carcinomas (ccRCCs). To determine whether opposing influences of HIF-1α and HIF-2α on c-Myc activity regulate human ccRCC progression, we analyzed VHL genotype and HIF-α expression in 160 primary tumors, which segregated into three groups with distinct molecular characteristics. Interestingly, ccRCCs with intact VHL, as well as pVHL-deficient, HIF-1α/HIF-2α expressing ccRCCs, exhibited enhanced Akt/mTOR and ERK/MAPK signaling. In contrast, pVHL-deficient ccRCCs expressing only HIF-2α displayed elevated c-Myc activity, resulting in enhanced proliferation and resistance to replication stress. These reproducible distinctions in ccRCC behavior delineate HIF-α effects on c-Myc in vivo and suggest molecular criteria for selecting targeted therapies.
(401891) Margaret Kidd
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supplementary tables and figures from No evidence for extrinsic post-zygotic isolation in a wild Saccharomyces yeast system
Creators: name: Charron, Guillaume
name: Landry, Christian R.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: supplementary figures and tables supporting the results
Operators of subprincipal type
Creators: name: Dencker, Nils
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35S05, 35A01, 58J40, 47G30

description: In this paper we consider the solvability of pseudodifferential operators when the principal symbol vanishes of at least second order at a non-radial involutive manifold $Σ_2$. We shall assume that the subprincipal symbol is of principal type with Hamilton vector field tangent to $Σ_2$ at the characteristics, but transversal to the symplectic leaves of $Σ_2$. We shall also assume that the subprincipal symbol is essentially constant on the leaves of $Σ_2$ and does not satisfy the Nirenberg-Treves condition ($Ψ$) on $Σ_2$. In the case when the sign change is of infinite order, we also need a condition on the rate of vanishing of both the Hessian of the principal symbol and the complex part of the gradient of the subprincipal symbol compared with the subprincipal symbol. Under these conditions, we prove that $P$ is not solvable.
description: Minor corrections and changes of previous version. Added Example 2.9. Accepted for publication in Analysis & PDE
title: Optimal management of IgG4-related disease in the abdomen
Creators: name: Farelo Villalobos, Javier
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: Biliary Tract / Gallbladder
subject: Pancreas
subject: CT
subject: MR
subject: Ultrasound
subject: Biopsy
subject: Diagnostic procedure
subject: Acute
subject: Cancer
subject: Inflammation

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Review of the main abdominal manifestations of IgG 4-mediated disease and it’s...
MixNet: Joining Force of Classical and Modern Approaches Toward the Comprehensive Pipeline in Motor Imagery EEG Classification
Creators: name: Autthasan, Phairot
name: Chaisaen, Rattanaphon
name: Phan, Huy
name: De Vos, Maarten
name: Wilaiprasitporn, Theerawit
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Human-Computer Interaction (cs.HC)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Recent advances in deep learning (DL) have significantly impacted motor imagery (MI)-based brain-computer interface (BCI) systems, enhancing the decoding of electroencephalography (EEG) signals. However, most studies struggle to identify discriminative patterns across subjects during MI tasks, limiting MI classification performance. In this article, we propose MixNet, a novel classification framework designed to overcome this limitation by utilizing spectral-spatial signals from MI data, along with a multitask learning architecture named MIN2Net, for classification. Here, the spectral-spatial signals are generated using the filter-bank common spatial patterns (FBCSPs) method on MI data. Since the multitask learning architecture is used for the classification task, the learning in each task may exhibit different generalization rates and potential overfitting across tasks. To address this issue, we implement adaptive gradient blending, simultaneously regulating multiple loss weights and adjusting the learning pace for each task based on its generalization/overfitting tendencies. Experimental results on six benchmark data sets of different data sizes demonstrate that MixNet consistently outperforms all state-of-the-art algorithms in subject-dependent and -independent settings. Finally, the low-density EEG MI classification results show that MixNet outperforms all state-of-the-art algorithms, offering promising implications for Internet of Thing (IoT) applications, such as lightweight and portable EEG wearable devices based on low-density montages.
description: Supplementary materials and source codes are available on-line at https://github.com/Max-Phairot-A/MixNet
Mitochondrial p32 Is a Critical Mediator of ARF-Induced Apoptosis
Creators: name: Zhang, Yanping
name: Itahana, Koji
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The shared exon 2 of the p14ARF-p16INK4a locus is frequently mutated in human cancers. However, in contrast to the exon 1β-encoded N-terminal half of ARF, the function of the exon 2-encoded C-terminal half of ARF has been elusive. Here, we report that the mitochondrial protein p32/C1QBP binds the ARF C terminus. We show that p32 is required for ARF to localize to mitochondria and induce apoptosis, and that ARF mutations specifically disrupting p32 binding can impair both of these functions. Wild-type ARF, but not a p32-binding-deficient ARF mutant, localizes to mitochondria, reduces mitochondrial membrane potential, and sensitizes cells to p53-induced apoptosis. These findings provide a potential explanation for the frequent human cancer mutations targeting the ARF C terminus.
Material and Methods from Nineteenth-century collapse of a benthic marine ecosystem on the open continental shelf.
Creators: name: Tomašových, Adam
name: Kidwell, Susan M.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences

description: Material and Methods with supplementary figures, tables, and age data
title: Congenital diseases of the corpus callosum: a pictorial review
Creators: name: Kebbou, Touda
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: CNS
subject: Neuroradiology brain
subject: CT
subject: MR
subject: Ultrasound
subject: eLearning
subject: Congenital
subject: Developmental disease

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To review the normal anatomy and embryology of the corpus callosum. To precise the role of each imaging modality in diagnosing congenital corpus callosum diseases. To review the different congenital diseases of the corpus callosum and their imaging...
(401892) Anne Knight Kidd
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Imaging of cystic lesions of the jaw - Not the Spielberg’s Jaws !
Creators: name: Ilangovan, Gurubharath
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Bones
subject: CT
subject: MR
subject: Plain radiographic studies
subject: Imaging sequences
subject: Surgery
subject: Cancer
subject: Cysts
subject: Fistula

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Cysts and cyst like lesion of mandible are a common finding in routine head and neck imaging. Knowledge about the various lesions of the mandible helps the patient clinically in assessing the pathology and etiology of the...
title: MR Imaging of wrist ligaments - The land of 9 bones!
Creators: name: Ilangovan, Gurubharath
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Bones
subject: Musculoskeletal soft tissue
subject: Musculoskeletal system
subject: MR
subject: Localisation
subject: Normal variants
subject: Athletic injuries
subject: Inflammation

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Detailed but simplified approach to the complex anatomy of wrist ligaments and their normal appearance in Magnetic resonance...
Novel Functionalities of Smart Home Devices for the Elastic Energy Management Algorithm
Creators: name: Powroźnik, Piotr
name: Szcześniak, Paweł
name: Sobolewski, Łukasz
name: Piotrowski, Krzysztof
Publisher: name: Basel : MDPI
Year: 2022
Subjects: subject: elastic energy management algorithm
subject: energy demand control
subject: GMDH neural networks
subject: GRASP algorithm
subject: regression method
subject: renewable energy sources
subject: smart appliances
subject: 620

description: Energy management in power systems is influenced by such factors as economic and ecological aspects. Increasing the use of electricity produced at a given time from renewable energy sources (RES) by employing the elastic energy management algorithm will allow for an increase in “green energy“ in the energy sector. At the same time, it can reduce the production of electricity from fossil fuels, which is a positive economic aspect. In addition, it will reduce the volume of energy from RES that have to be stored using expensive energy storage or sent to other parts of the grid. The model parameters proposed in the elastic energy management algorithm are discussed. In particular, attention is paid to the time shift, which allows for the acceleration or the delay in the start-up of smart appliances. The actions taken by the algorithm are aimed at maintaining a compromise between the user’s comfort and the requirements of distribution network operators. Establishing the value of the time shift parameter is based on GMDH neural networks and the regression method. In the simulation studies, the extension of selected activities related to the tasks performed in households and its impact on the user’s comfort as well as the response to the increased generation of energy from renewable energy sources have been verified by the simulation research presented in this article. The widespread use of the new functionalities of smart appliance devices together with the elastic energy management algorithm is planned for the future. Such a combination of hardware and software will enable more effective energy management in smart grids, which will be part of national power systems.
BINO SHAKLINING ENERGIYA SAMARADORLIGIGA TA'SIRINI HISOBGA OLISH
Creators: name: Shungaraeva, Gulmira
name: Mirolimov, Mirrahim
Publisher: name: Zenodo
Year: 2023

description: Bino rejalarining konfiguratsiya variantlarining ularning energiya sarfi bo'yicha fazoviy xususiyatlari bilan o'zaro bog'liqligi ko'rib chiqiladi. Binolarning shakllarini hajmli rejalashtirish echimlarini tadqiq qilishning dolzarbligi asoslanadi energiya samaradorligini hisobga olgan holda. Tadqiqot ob'ekti sifatida energiya samaradorligini hisobga olgan holda bino shakllarining eng keng tarqalgan volumetrik-fazoviy konfiguratsiyalarini tanlaymiz. Binoning asosiy  rejalashtirish parametrlarini va ularning issiqlik yo'qotilishiga ta'siri uchun qurilish maydonlarining o'zgarishi zamin maydonining o'zgarishiga bog'liqligini aniqlashga imkon beradigan grafik materiallar zarur shart-sharoitlarni tahlil qilish misollari keltirilgan. Ushbu taqqoslash binolarni energiya tejash tamoyillarini hisobga olgan holda qurish uchun energiya tejaydigan va oqilona tuzilgan hajmli rejalashtirish echimini aniqlash uchun amalga oshiriladi.
CDK Inhibitor p18INK4c Is a Downstream Target of GATA3 and Restrains Mammary Luminal Progenitor Cell Proliferation and Tumorigenesis
Creators: name: Xiong, Yue
name: Bai, Feng
name: Ho, I. Cheng
name: Smith, Matthew D.
name: Pei, Xin Hai
name: Usary, Jerry
name: Fan, Cheng
name: Perou, Charles M.
name: Pai, Sung Yun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Mammary epithelia are composed of luminal and myoepithelial/basal cells whose neoplastic transformations lead to distinct types of breast cancers with diverse clinical features. We report that mice deficient for the CDK4/6 inhibitor p18Ink4c spontaneously develop ER-positive luminal tumors at a high penetrance. Ink4c deletion stimulates luminal progenitor cell proliferation at pubertal age and maintains an expanded luminal progenitor cell population throughout life. We demonstrate that GATA3 binds to and represses INK4C transcription. In human breast cancers, low INK4C and high GATA3 expressions are simultaneously observed in luminal A type tumors and predict a favorable patient outcome. Hence, p18INK4C is a downstream target of GATA3, constrains luminal progenitor cell expansion and suppresses luminal tumorigenesis in the mammary gland.
A unifying explanation of complex frequency spectra of gamma Dor, SPB and Be stars: combination frequencies and highly non-sinusoidal light curves
Creators: name: Kurtz, Donald W.
name: Shibahashi, Hiromoto
name: Murphy, Simon J.
name: Bedding, Timothy R.
name: Bowman, Dominic M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: There are many Slowly Pulsating B (SPB) stars and gamma Dor stars in the Kepler Mission data set. The light curves of these pulsating stars have been classified phenomenologically into stars with symmetric light curves and with asymmetric light curves. In the same effective temperature ranges as the gamma Dor and SPB stars, there are variable stars with downward light curves that have been conjectured to be caused by spots. Among these phenomenological classes of stars, some show `frequency groups' in their amplitude spectra that have not previously been understood. While it has been recognised that nonlinear pulsation gives rise to combination frequencies in a Fourier description of the light curves of these stars, such combination frequencies have been considered to be a only a minor constituent of the amplitude spectra. In this paper we unify the Fourier description of the light curves of these groups of stars, showing that many of them can be understood in terms of only a few base frequencies, which we attribute to g mode pulsations, and combination frequencies, where sometimes a very large number of combination frequencies dominate the amplitude spectra. The frequency groups seen in these stars are thus tremendously simplified. We show observationally that the combination frequencies can have amplitudes greater than the base frequency amplitudes, and we show theoretically how this arises. Thus for some gamma Dor and SPB stars combination frequencies can have the highest observed amplitudes. Among the B stars are pulsating Be stars that show emission lines in their spectra from occasional ejection of material into a circumstellar disk. Our analysis gives strong support to the understanding of these pulsating Be stars as rapidly rotating SPB stars, explained entirely by g mode pulsations.
description: Accepted MNRAS; 17 pages
CryptoAnalytics: Cryptocoins Price Forecasting with Machine Learning Techniques
Creators: name: De Rosa, Pasquale
name: Felber, Pascal
name: Schiavoni, Valerio
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: FOS: Computer and information sciences

description: This paper introduces CryptoAnalytics, a software toolkit for cryptocoins price forecasting with machine learning (ML) techniques. Cryptocoins are tradable digital assets exchanged for specific trading prices. While history has shown the extreme volatility of such trading prices, the ability to efficiently model and forecast the time series resulting from the exchange price volatility remains an open research challenge. Good results can been achieved with state-of-the-art ML techniques, including Gradient-Boosting Machines (GBMs) and Recurrent Neural Networks (RNNs). CryptoAnalytics is a software toolkit to easily train these models and make inference on up-to-date cryptocoin trading price data, with facilities to fetch datasets from one of the main leading aggregator websites, i.e., CoinMarketCap, train models and infer the future trends. This software is implemented in Python. It relies on PyTorch for the implementation of RNNs (LSTM and GRU), while for GBMs, it leverages on XgBoost, LightGBM and CatBoost.
Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases
Creators: name: Hung, Mien Chie
name: Mills, Gordon B.
name: Perou, Charles M.
name: Lu, Yiling
name: Liu, Wenbin
name: Cui, Xiaojiang
name: Lee, Adrian V.
name: Fang, Xianjun
name: Liu, Shuying
name: Zhang, Fan
name: Coombes, Kevin
name: Umezu-Goto, Makiko
name: Murph, Mandi
name: Murrow, George
name: Muller, William
name: Yu, Shuangxing
name: Stephens, L. Clifton
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Lysophosphatidic acid (LPA) acts through high affinity G protein-coupled receptors to mediate a plethora of physiological and pathological activities associated with tumorigenesis. LPA receptors and autotaxin (ATX/LysoPLD), the primary enzyme producing LPA, are aberrantly expressed in multiple cancer lineages. However, the role of ATX and LPA receptors in the initiation and progression of breast cancer has not been evaluated. We demonstrate that expression of ATX or each Edg-family LPA receptor in mammary epithelium of transgenic mice is sufficient to induce a high frequency of late-onset, estrogen receptor (ER) positive, invasive and metastatic mammary cancer. Thus ATX and LPA receptors can contribute to the initiation and progression of breast cancer.
From Lab-on-chip to Lab-in-App: Challenges towards silicon photonic biosensors product developments
Creators: name: Mai, Andreas
name: Mai, Christian
name: Steglich, Patrick
Publisher: name: Amsterdam : Elsevier
Year: 2022
Subjects: subject: Integrated optical sensors
subject: Interchangeable sensor chip
subject: Optical ring resonators
subject: Photonic biosensor
subject: Photonic integrated circuits
subject: Refractive index sensing
subject: Silicon photonic sensors
subject: 530

description: This work presents and evaluates different approaches of integrated optical sensors based on photonic integrated circuit (PIC) technologies for refractive index sensing. Bottlenecks in the fabrication flow towards an applicable system are discussed that hinder a cost-effective mass-production for disposable sensor chips. As sensor device, a waveguide coupled micro-ring based approach is chosen which is manufactured in an 8” wafer level process. We will show that the co-integration with a reproducible, scalable and low-cost microfluidic interface is the main challenge which needs to be overcome for future application of silicon technology based PIC sensor chips.
An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction
Creators: name: Zhang, Yanping
name: Mao, Hua
name: Deisenroth, Chad
name: Jin, Aiwen
name: Lindström, Mikael S.
name: Bhat, Krishna
name: Macias, Everardo
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: In vitro studies have shown that inhibition of ribosomal biogenesis can activate p53 through ribosomal protein (RP)-mediated suppression of Mdm2 E3 ligase activity. To study the physiological significance of the RP-Mdm2 interaction, we generated mice carrying a cancer-associated cysteine-to-phenylalanine substitution in the zinc finger of Mdm2 that disrupted its binding to RPL5 and RPL11. Mice harboring this mutation, although retain normal p53 response to DNA damage, lack p53 response to perturbations in ribosome biogenesis. Loss of RP-Mdm2 interaction significantly accelerates Eμ-Myc induced lymphomagenesis. Furthermore, ribosomal perturbation induced p53 response does not require tumor suppressor p19Arf. Collectively, our findings establish RP-Mdm2 interaction as a genuine p53 stress-signaling pathway activated by aberrant ribosomal biogenesis and essential for safeguarding against oncogenic c-Myc-induced tumorigenesis.
title: Radiology of Leprosy: Catching the claw
Creators: name: Ilangovan, Gurubharath
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Musculoskeletal system
subject: Neuroradiology peripheral nerve
subject: Soft tissues / Skin
subject: MR
subject: Plain radiographic studies
subject: Ultrasound
subject: Abscess delineation
subject: Complications
subject: Surgery
subject: Arthritides
subject: Demineralisation-Bone
subject: Infection

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Though radiology has a limited role in the current era, we have provided with various classical findings in X-ray, ultrasound and Magnetic resonance imaging which will aid in the...