cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: of High prevalence of HIV-1 transmitted drug resistance among therapy-naĂŻve Burmese entering travelers at Dehong ports in Yunnan, China
Creators: name: Xuan, Qicai
name: Liang, Shuwen
name: Qin, Weihong
name: Yang, Shuting
name: Zhang, A-mei
name: Zhao, Ting
name: Su, Hui
name: Xia, Zhiqing
name: Wang, Binghui
name: Xia, Xueshan
Publisher: name: figshare
Year: 2018
Subjects: subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Figure S1. Maximum likelihood method was chosen for phylogenetic analysis and constructed phylogenetic tree using all the pol gene sequences. (PDF 133Â kb)
Additional file 1 of Barriers and facilitators for disease registry systems: a mixed-method study
Creators: name: Lazem, Mina
name: Sheikhtaheri, Abbas
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Interview guide and sample interviewees’ quotes.
Detection of active SARS-CoV-2 in cough aerosols from COVID-19 patients
Creators: name: de Sousa, Nuno Rufino
name: Margerie, Lucille
name: Steponaviciute, Laura
name: Roux, Julie
name: Kinahan, Matthew W.
name: Olsson, David
name: Ásgeirsson, Hilmir
name: Udekwu, Klas I.
name: Rothfuchs, Antonio Gigliotti
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an airborne pathogen, but detection of infectious SARS-CoV-2 in air and in particular the introduction of the virus into the environment by different human expiratory manoeuvres is not well studied. The aim of this study was to investigate the presence of SARS-CoV-2 in cough from coronavirus disease of 2019 (COVID-19) in-patients and to study contamination of the virus in the patient’s environment. Detection of SARS-CoV-2 in cough was analyzed by PCR, culture and imaging. Detection in cough was compared to presence of the virus in air and on surfaces from patient rooms. Twenty-five patients in 21 rooms were included in the study. SARS-CoV-2 RNA was found in cough aerosols from 16 out of 22 patients that produced voluntary cough. As demonstrated by plaque-forming unit assays, active virus was isolated from 11 of these 16 patients. Using mainly molecular detection, the virus was also found in air, on high-contact surfaces, and no-touch surfaces from the room of the COVID-19 patients. These results show that infectious SARS-CoV-2 circulating in air can originate from patient cough and should be considered against the risk of acquiring COVID-19 through inhalation.
title: Vox et Silentium Dei
title: A Socio-Cognitive Linguistic Theory of Religious Violence
titleType: Subtitle
Creators: name: Kibbey, Tyler
Publisher: name: University of Kentucky Libraries
Year: 2020
Subjects: subject: Linguistics
subject: FOS: Languages and literature

description: Contemporary research in the study of language and cognition frequently characterizes religious metaphors as either monoliths of experience or stable synchronic structures, if not both. In addition, by virtue of how the foundational theory of this paper, Conceptual Metaphor Theory, has been situated in the literature, pre-modern theist writing on figurative language has been largely ignored. This has resulted in a general application of Conceptual Metaphor Theory to religious language which characterizes religious experience as phenomenologically invalid with the contingent effect of contradicting the basic experiential nature of metaphor. Here, I account for these principal theoretical discrepancies through an exploration of the qualities and varieties of religious metaphor, culminating in a proposed amendment to Conceptual Metaphor Theory. In the latter portion of my thesis, I apply the amended theory to the journal of the American missionary John Allen Chau to demonstrate its theoretical efficacy in relation to an analysis of sovereignty metaphors within Chau’s evangelical ideology.
description: © 2020 Tyler Everett Kibbey
Additional file 1 of RaptorX-Angle: real-value prediction of protein backbone dihedral angles through a hybrid method of clustering and deep learning
Creators: name: Gao, Yujuan
name: Wang, Sheng
name: Deng, Minghua
name: Xu, Jinbo
Publisher: name: figshare
Year: 2018
Subjects: Molecular Biology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Mathematical Sciences not elsewhere classified
Developmental Biology

description: Supplementary Material. This additional file contains two parts: S1. supplementary methods for vector representation and normalisation of angles, and also feature generation; S2. supplementary results for determining regularization factor, testing different network architectures, testing different number of labels to use for real value prediction and performance comparison. (PDF 250 kb)
Data Dictionary
Creators: name: Abhishek Kala
name: Atkinson, Sam
name: Chetan Tiwari
name: Mikler, Armin
Publisher: name: figshare
Year: 2017
Subjects: subject: 50103 Invasive Species Ecology
subject: FOS: Earth and related environmental sciences
subject: Environmental Science

description: Data Dictionary for WNV clinical data (human cases and infected dead birds cases) for paper "A comparison of least squares regression and geographically weighted regression modeling of West Nile virus risk based on environmental parameters"
Additional file 2 of Barriers and facilitators for disease registry systems: a mixed-method study
Creators: name: Lazem, Mina
name: Sheikhtaheri, Abbas
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2. Consolidated criteria for reporting qualitative studies (COREQ) checklist.
Fourier transform infrared spectroscopic imaging of live cells
Creators: name: Turner, Benjamin
Publisher: name: Imperial College London
Year: 2017

description: There is an increasing demand for label-free methods of cell analysis in fields such as cell biology, drug discovery, and medical diagnostics. Many optical techniques have been developed to this end, which typically use physical properties such as refractive index to better visualise cells without the need for fluorescent markers. However, if chemical information about the sample is desired then these techniques provide limited information. Fourier Transform Infrared (FTIR) spectroscopic imaging has emerged as a powerful analytical tool that has been used to study a wide variety of biological samples. By using a focal plane array (FPA) detector, thousands of spatially resolved infrared spectra can be recorded simultaneously, creating a chemical map of a sample. FTIR spectroscopic imaging is also a label-free and inherently non-destructive form of measurement. However, due to the high molar absorptivity of water, the use of FTIR spectroscopic imaging to study living cells remains challenging. As cells must be maintained in an aqueous environment, severe restrictions are placed on the maximum path lengths that can be used in infrared spectroscopic imaging experiments. The purpose of this research was to further develop the application of micro attenuated total reflection (ATR)-FTIR spectroscopic imaging to the study of live cells. Micro ATR-FTIR spectroscopic imaging avoids the path length restriction seen in transmission mode, as the path length is not dependent on the sample’s thickness. This means micro ATR-FTIR spectroscopic imaging can be done in bulk aqueous environments. A robust methodology to culture adherent cells directly on an ATR crystal surface was developed, and the extent to which subcellular features can be visualised was investigated. Multiple-reflection ATR spectroscopy of live cells is also presented. This thesis then presents for the first time the detection of an exogenous molecule within a living cell by FTIR spectroscopic imaging. The recently developed analysis method disrelation mapping was also applied to a spectroscopic imaging dataset of a single living cell. Evidence of a different distribution of molecular states of water, compared to that seen in bulk water, was detected in living cells.
ALTERATION OF AMYLASE AND PHOSPHATASE IN Macrotyloma uniflorum UNDER INFLUENCE OF CADMIUM, MERCURY AND ZINC STRESSES
Creators: name: Naji, Khalid
name: Varadahally R. Devaraj
Publisher: name: figshare
Year: 2017
Subjects: subject: 60203 Ecological Physiology
subject: FOS: Biological sciences
subject: Biochemistry

description: AbstractPhysical weathering of parent rocks, mining, and other anthropogenic activities lead to impermissible levels of heavy metals in plant tissues. Effect of Cd2+, Hg2+, and Zn2+ on metabolic enzymes, Amylase (EC; 3.2.1.1), and AP (EC; 3.1.3.2), were studied to assess horse gram response to these heavy metal stress. Enzyme activity and TC were evaluated. Amylase decreased in response to increasing Cd2+ concentration, with great impact at 48-72h. It rose under 5 ppm Hg2+, while dropped under 10 ppm beyond 24h reaching ~25% of control, and recovered with time to reach 80-90% under 20 ppm. Under Zn2+ stress, amylase rose in concentration- and time-dependent manner. AP declined under metal stress in concentration, time-dependent manner, except at 100 ppm Zn2+. TC fluctuated in metal-specific manner with positive influence by Zn2+ (300-600 ppm) and Cd2+ (100-200 ppm) at 24 h. TC diminished under Cd2+ stress beyond 24 h, and over entire duration under Hg2+ stress. It can deduce that Hg2+ and Cd2+ exhibited toxic effects on horse gram while Zn2+ had positive effects. Amylase responded negatively to Hg2+, positively to Zn2+, and showed mixed response to Cd2+. AP levels decreased under metal stresses, except Zn2+.
ЗНАЧЕНИЕ ФРАЗ В ПРОЦЕССЕ ИЗУЧЕНИЯ ФРАНЦУЗСКОГО ЯЗЫКА
Creators: name: Азамжонова Сарвиноз Шухратовна Студентка 1 курса Узбекского государственного университитета мировых языков Ташкент, Узбекистан
Publisher: name: Zenodo
Year: 2024

description: Французский язык использует словосочетания для выражения многих понятий, которые в русском языке обозначаются, одним словом, нередко производным (de bonne heure «спозаранку», mettre hors d’état de nuire и т.п.). Вместе с тем во французской фразеологии используются в большей степени переносные (специализированные) значения слов, нежели их образные значения.
Additional file 1 of Vaspin promotes chondrogenic differentiation of BMSCs via Akt activation in osteoarthritis
Creators: name: Wang, Junfeng
name: Zhang, Keshi
name: Zhang, Shaolong
name: Guan, Zhenpeng
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1 Supplementary Fig. 1. The immunohistochemical staining results.
Additional file 2 of Vaspin promotes chondrogenic differentiation of BMSCs via Akt activation in osteoarthritis
Creators: name: Wang, Junfeng
name: Zhang, Keshi
name: Zhang, Shaolong
name: Guan, Zhenpeng
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Supplementary Fig. 2. The original blots in western blotting.
MOESM1 of Repair of articular cartilage defects with intra-articular injection of autologous rabbit synovial fluid-derived mesenchymal stem cells
Creators: name: Jia, Zhaofeng
name: Liu, Qisong
name: Liang, Yujie
name: Li, Xingfu
name: Xu, Xiao
name: Ouyang, Kan
name: Xiong, Jianyi
name: Wang, Daping
name: Duan, Li
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Ecology
subject: Developmental Biology

description: Additional file 1: Figure S1. Surgical procedures of rabbit articular cartilage defect introduction and intra-articular injections of rbSF-MSCs. (A) A cylindrical full-thickness cartilage defect (3.5 mm in diameter and 1.5 mm in depth) was created on the trochlear groove using a special drill. (B) The cells were articularly injected in the knee joint of experimental rabbits using using large 18G size needles.
MOESM2 of Repair of articular cartilage defects with intra-articular injection of autologous rabbit synovial fluid-derived mesenchymal stem cells
Creators: name: Jia, Zhaofeng
name: Liu, Qisong
name: Liang, Yujie
name: Li, Xingfu
name: Xu, Xiao
name: Ouyang, Kan
name: Xiong, Jianyi
name: Wang, Daping
name: Duan, Li
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology

description: Additional file 2: Table S1. International Cartilage Repair Society macroscopic evaluation of cartilage repair.
The bent conformation of poly(A)-binding protein induced by RNA-binding is required for its translational activation function
Creators: name: Hong, Ka Young
name: Lee, Seung Hwan
name: Sohyun Gu
name: Eunah Kim
name: Sihyeon An
name: Junyoung Kwon
name: Jong-Bong Lee
name: Jang, Sung Key
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: A recent study revealed that poly(A)-binding protein (PABP) bound to poly(A) RNA exhibits a sharply bent configuration at the linker region between RNA-recognition motif 2 (RRM2) and RRM3, whereas free PABP exhibits a highly flexible linear configuration. However, the physiological role of the bent structure of mRNA-bound PABP remains unknown. We investigated a role of the bent structure of PABP by constructing a PABP variant that fails to form the poly(A)-dependent bent structure but maintains its poly(A)-binding activity. We found that the bent structure of PABP/poly(A) complex is required for PABP's efficient interaction with eIF4G and eIF4G/eIF4E complex. Moreover, the mutant PABP had compromised translation activation function and failed to augment the formation of 80S translation initiation complex in an in vitro translation system. These results suggest that the bent conformation of PABP, which is induced by the interaction with 3′ poly(A) tail, mediates poly(A)-dependent translation by facilitating the interaction with eIF4G and the eIF4G/eIF4E complex. The preferential binding of the eIF4G/eIF4E complex to the bent PABP/poly(A) complex seems to be a mechanism discriminating the mRNA-bound PABPs participating in translation from the idling mRNA-unbound PABPs.
Seroprevalence of human herpes viruses in France, 2018–2022: a multilevel regression and poststratification approach
Creators: name: Supplisson, Olivier
name: Visseaux, Benoit
name: Haim-Boukobza, Stéphanie
name: Boutolleau, David
name: Alizon, Samuel
name: Burrel, Sonia
name: Sofonea, Mircea T.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Information related to herpes simplex virus 1 and 2 (HSV-1 and 2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV) seroprevalence in France is either lacking, incomplete, or outdated, despite their public health burden. We used routinely collected serological data between 2018 and 2022 to estimate HSV-1, HSV-2, VZV, EBV, and CMV seroprevalence in France. To account for demographic differences between our analytic samples and the French population and get estimates for sparsely sampled districts and age classes, we used a multilevel regression and poststratification approach combined with Bayesian model averaging via stacking weights. The observed seroprevalence (number of positive tests/number of tests) were 64.6% (93,294/144,424), 16.9% (24,316/144,159), 93.0% (141,419/152,084), 83.4% (63,199/75, 781), and 49.0% (23,276/47,525), respectively, for HSV-1, HSV-2, VZV, EBV, and CMV. Between 2018 and 2022, France had a model-based average (equal-tailed interval at 95%) expected seroprevalence equal to 61.1% (60.7,61.5), 14.5% (14.2,14.81), 89.5% (89.3,89.8), 85.6% (85.2,86.0), and 50.5% (49.3,51.7), respectively, for HSV-1, HSV-2, VZV, EBV, and CMV infections. We found an almost certain lower expected seroprevalence in Metropolitan France than in overseas territories for all viruses but VZV, for which it was almost certainly greater. The expected seroprevalences were likely greater among females for all viruses. Our results relied on the assumption that individuals were sampled at random conditionally to variables used to build the poststratification table. The analysis highlights spatial and demographic patterns in seroprevalence that should be considered for designing tailored public health policies.
Adipokines induce catabolism of newly synthesized matrix in cartilage and meniscus tissues
Creators: name: Nishimuta, James F.
name: Levenston, Marc E.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Purpose: Altered synovial levels of various adipokines (factors secreted by fat as well as other tissues) have been associated with osteoarthritis (OA) onset and progression. However, the metabolic effects of adipokines on joint tissues, in particular the fibrocartilaginous menisci, are not well understood. This study investigated effects of several adipokines on release of recently synthesized extracellular matrix in bovine cartilage and meniscus tissue explants. Materials and methods: After labeling newly synthesized proteins and sulfated glycosaminoglycans (sGAGs) with 3H-proline and 35S-sulfate, respectively; bovine cartilage and meniscus tissue explants were cultured for 6 days in basal medium (control) or media supplemented with adipokines (1 µg/ml of leptin, visfatin, adiponectin, or resistin) or 20 ng/ml interleukin-1 (IL-1). Release of radiolabel and sGAG to the media during culture and the final explant water, DNA, sGAG, and retained radiolabel were measured. Matrix metalloproteinase (MMP-2) and MMP-3 activities were assessed using gelatin and casein zymography, respectively. Results: Water and DNA contents were not significantly altered by any treatment. Visfatin, adiponectin, resistin, and IL-1 stimulated sGAG release from meniscus, whereas only IL-1 stimulated sGAG release from cartilage. Release of 3H and 35S was stimulated not only by resistin and IL-1 in meniscus but also by IL-1 in cartilage. Retained 3H was unaltered by any treatment, while retained 35S was reduced by visfatin, resistin, and IL-1 in meniscus and by only IL-1 in cartilage. Resistin and IL-1 elevated active MMP-2 and total MMP-3 in meniscus, whereas cartilage MMP-3 activity was elevated by only IL-1. Conclusions: Resistin stimulated rapid and extensive catabolism of meniscus tissue, similar to IL-1, whereas adipokines minimally affected cartilage. Release of newly synthesized matrix was similar to overall release in both tissues. These observations provide further indications that meniscal tissue is more sensitive to pro-inflammatory factors than cartilage and also suggest further study of resistin’s role in OA.
Desintoxiquemos nós! Conhecimento para o futuro
Creators: name: Pinto, Valeria
name: Bertoni, Federico
name: Borrelli, Davide
name: Pievatolo, Maria Chiara
Publisher: name: Zenodo
Year: 2020
Subjects: avaliação da pesquisa
liberdade acadêmica
universidade
Italia

description: Versão portuguesa de um manifesto italiano contra as restrições burocráticas que estrangulam a universidade pública na Itália por causa de um sistema administrativo e centralizado de avaliação da pesquisa que está minando a própria liberdade acadêmica garantida pela Constituição italiana.
Additional file 1 of Co-creation of an exercise inventory to improve scapular stabilization and control among individuals with rotator cuff-related shoulder pain: a survey-based study amongst physiotherapists
Creators: name: Dubé, Marc-Olivier
name: Arel, Jasmine
name: Paquette, Philippe
name: Roy, Jean-Sébastien
name: Desmeules, François
name: Gagnon, Dany H.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1. Supplementary File 1: SSE inventory.
First cases of mpox Clade I outside of Africa: genetic insights on its evolution
Creators: name: Branda, Francesco
name: Ceccarelli, Giancarlo
name: Ciccozzi, Massimo
name: Scarpa, Fabio
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: First cases of mpox Clade I outside of Africa: genetic insights on its evolution
New diorganotin(IV) complexes of tridentate Schiff bases derived from 1,3-indanedione derivative: Synthesis, spectral studies and in vitro antimicrobial activities
Creators: name: Khatkar, Priyanka
name: Sonika Asija
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: A series of 16 pentacoordinated diorganotin(IV) complexes has been reported here which were synthesized by reacting the appropriate dialkyl/diaryltin(IV)dichloride with four newly synthesized Schiff bases. The dianionic tridentate(ONO) Schiff base hydrazones have been conveniently synthesized in good yields by reacting 2,2-(3-methylbutanoyl)-1H-indene-1,3(2H)-dione with different acid hydrazides. The structures of the synthesized Schiff bases and their complexes have been established on the basis of IR, mass spectra, 1H, 13C, 119Sn NMR spectroscopy and different physical techniques. The compounds have also been screened for antimicrobial activity against four bacterial strains, i.e., Gram positive Bacillus ceres (MTCC 10072), Styphyllococus aureus (MTCC 2901) and Gram negative Escherichia.coli (MTCC 732), Pseudomonas aeruginosa (MTCC 424), and three fungal strains, i.e., Aspergillus flavus (ITCC 7680), Aspergillus niger (MTCC 7678), Candida albicans (MTCC 227) by serial dilution method and it was found that most of the synthesized compounds were relatively active with the standard drugs especially in Gram positive bacteria and fungal strains.
Validation of a parametric finite element human femur model
Creators: name: Klein, Katelyn F.
name: Jingwen Hu
name: Reed, Matthew P.
name: Schneider, Lawrence W.
name: Rupp, Jonathan D.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Objective: Finite element (FE) models with geometry and material properties that are parametric with subject descriptors, such as age and body shape/size, are being developed to incorporate population variability into crash simulations. However, the validation methods currently being used with these parametric models do not assess whether model predictions are reasonable in the space over which the model is intended to be used. This study presents a parametric model of the femur and applies a unique validation paradigm to this parametric femur model that characterizes whether model predictions reproduce experimentally observed trends. Methods: FE models of male and female femurs with geometries that are parametric with age, femur length, and body mass index (BMI) were developed based on existing statistical models that predict femur geometry. These parametric FE femur models were validated by comparing responses from combined loading tests of femoral shafts to simulation results from FE models of the corresponding femoral shafts whose geometry was predicted using the associated age, femur length, and BMI. The effects of subject variables on model responses were also compared with trends in the experimental data set by fitting similarly parameterized statistical models to both the results of the experimental data and the corresponding FE model results and then comparing fitted model coefficients for the experimental and predicted data sets. Results: The average error in impact force at experimental failure for the parametric models was 5%. The coefficients of a statistical model fit to simulation data were within one standard error of the coefficients of a similarly parameterized model of the experimental data except for the age parameter, likely because material properties used in simulations were not varied with specimen age. In simulations to explore the effects of femur length, BMI, and age on impact response, only BMI significantly affected response for both men and women, with increasing BMI producing higher impact forces. Conclusions: Impactor forces from simulations, on average, matched experimental values at the time of failure. In addition, the simulations were able to match the trends in the experimental data set.
MOESM3 of Repair of articular cartilage defects with intra-articular injection of autologous rabbit synovial fluid-derived mesenchymal stem cells
Creators: name: Jia, Zhaofeng
name: Liu, Qisong
name: Liang, Yujie
name: Li, Xingfu
name: Xu, Xiao
name: Ouyang, Kan
name: Xiong, Jianyi
name: Wang, Daping
name: Duan, Li
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 3: Table S2. The ICRS Visual Histological Assessment Scale.
Additional file 1 of A novel Vascular Leak Index identifies sepsis patients with a higher risk for in-hospital death and fluid accumulation
Creators: name: Chandra, Jay
name: Armengol de la Hoz, Miguel A.
name: Lee, Gwendolyn
name: Lee, Alexandria
name: Thoral, Patrick
name: Elbers, Paul
name: Lee, Hyung-Chul
name: Munger, John S.
name: Celi, Leo Anthony
name: Kaufman, David A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: Computational Biology

description: Additional file 1. Supplementary Material.
Self-regulation of driving speed among distracted drivers: An application of driver behavioral adaptation theory
Creators: name: Oviedo-Trespalacios, Oscar
name: Md. Mazharul Haque
name: King, Mark
name: Washington, Simon
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: Objective: The adaptive behavior of mobile phone–distracted drivers has been a topic of much discussion in the recent literature. Both simulator and naturalistic studies suggest that distracted drivers generally select lower driving speeds; however, speed adaptation is not observed among all drivers, and the mechanisms of speed selection are not well understood. The aim of this research was to apply a driver behavioral adaptation model to investigate the speed adaptation of mobile phone–distracted drivers. Methods: The speed selection behavior of drivers was observed in 3 phone conditions including baseline (no conversation) and hands-free and handheld phone conversations in a high-fidelity driving simulator. Speed adaptation in each phone condition was modeled as a function of secondary task demand and self-reported personal/psychological characteristics with a system of seemingly unrelated equations (SURE) accounting for potential correlations due to repeated measures experiment design. Results: Speed adaptation is similar between hands-free and handheld phone conditions, but the predictors of speed adaptation vary across the phone conditions. Though perceived workload of secondary task demand, self-efficacy, attitude toward safety, and driver demographics were significant predictors of speed adaptation in the handheld condition, drivers' familiarity with the hands-free interface, attitude toward safety, and sensation seeking were significant predictors in the hands-free condition. Drivers who reported more positive safety attitudes selected lower driving speeds while using phones. Conclusion: This research confirmed that behavioral adaptation models are suitable for explaining speed adaptation of mobile phone distracted drivers, and future research could be focused on further theoretical refinement.
Additional file 1 of The economic burden of prostate cancer in Eswatini
Creators: name: Ngcamphalala, Cebisile
name: Östensson, Ellinor
name: Ginindza, Themba G.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Science Policy
subject: Plant Biology

description: Additional file 1. Direct non-medical costs patient questionnaires.pdf
title: Communicative competence in Indonesian
title: language choice in inter-ethnic interactions in Semarang
titleType: Subtitle
Creators: name: Goebel, Zane
Publisher: name: Charles Darwin University
Year: 2000

description: The main aim of this research is to examine inter-ethnic interactions that occurred in two neighborhoods (RT) in Semarang, Indonesia, in order to explore how code choice and the use of prosody figured in these speaker's communicative competence. The motivation for doing this study was to provide some input into what appeared to be sociolinguistically uninformed debates about the teaching of variety in Indonesian language programs. This research utilized a number of theoretical approaches and methods to the study of language, most notably Hymes' (1972b, 1974a) "Ethnography of Communication", Gumperz's (1982a) "Interactional Sociolinguistics", and Myers-Scotton's (1993a) "Markedness" approach to code choice. Essentially this meant using these approaches to demonstrate how contextualization cues like code choice and prosody (i.e silence, intonation, pitch, tempo) were used in real-time interaction to signal intent and to interpret meaning, while also demonstrating how the use of these cues related to the wider speech community's daily social life. The most significant finding was that ngoko Javanese was being used to signal relative familiarity in inter-ethnic interactions, as among the Javanese alone. Non-standard Indonesian was generally used in inter-ethnic interactions to signal more distant relationships, while kromo Javanese was used to signal this among the Javanese themselves. In inter-ethnic interactions the use of prosodic features such as silence tended to match the use of code for indicating degrees of familiarity (i.e. latching and overlap used among familiars and pauses among unfamiliars) and it was found that inter-turn silence were generally symmetrical. This was found to be related to the general lack of instances of miscommunication, as was the finding that speakers tended to accomodate toward their partner's use of silence. Accordingly, it is argued that part of being a communicatively competent Indonesian means being able to choose a code to indicate whether one is friendly or distant toward one's interlocutor and having the ability to accommodate towards the code choice and prosodic patterns of one's conversational partner. The implications of this for Indonesian language programs might best be put by replacing questions like "Which variety of Indonesian should we teach?" with a question like "What are the parameters of social meaning that the use of one code instead of another will have?"
Additional file 1: of Basic leucine zipper transcription factor SlbZIP1 mediates salt and drought stress tolerance in tomato
Creators: name: Zhu, Mingku
name: Meng, Xiaoqing
name: Cai, Jing
name: Li, Ge
name: Dong, Tingting
name: Li, Zongyun
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology

description: Figure S1. Relative expression profiles of SlbZIP07, SlbZIP10 and SlbZIP39 in the leaves of WT and SlbZIP1-RNAi lines under normal conditions. (DOCX 77 kb)
title: 01_2166
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Detection of the toughest: Pedestrian injury risk as a smooth function of age
Creators: name: Niebuhr, Tobias
name: Junge, Mirko
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: Objective: Though it is common to refer to age-specific groups (e.g., children, adults, elderly), smooth trends conditional on age are mainly ignored in the literature. The present study examines the pedestrian injury risk in full-frontal pedestrian-to–passenger car accidents and incorporates age—in addition to collision speed and injury severity—as a plug-in parameter. Methods: Recent work introduced a model for pedestrian injury risk functions using explicit formulae with easily interpretable model parameters. This model is expanded by pedestrian age as another model parameter. Using the German In-Depth Accident Study (GIDAS) to obtain age-specific risk proportions, the model parameters are fitted to the raw data and then smoothed by broken-line regression. Results: The approach supplies explicit probabilities for pedestrian injury risk conditional on pedestrian age, collision speed, and injury severity under investigation. All results yield consistency to each other in the sense that risks for more severe injuries are less probable than those for less severe injuries. As a side product, the approach indicates specific ages at which the risk behavior fundamentally changes. These threshold values can be interpreted as the most robust ages for pedestrians. Conclusions: The obtained age-wise risk functions can be aggregated and adapted to any population. The presented approach is formulated in such general terms that in can be directly used for other data sets or additional parameters; for example, the pedestrian's sex. Thus far, no other study using age as a plug-in parameter can be found.
Additional file 1 of The effect of co-ethnic social capital on immigrants' labor market integration: a natural experiment
Creators: name: Gërxhani, Klarita
name: Kosyakova, Yuliya
Publisher: name: figshare
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology

description: Additional file 1. Appendix A. Methodological tools to address endogeneity of (co-ethnic) social networks. Appendix B. Allocation of refugees, ethnic Germans and Jewish immigrants in Germany. Appendix C. Information about the coding of variables. Appendix D. Comparison of model specifications. Appendix E. Models of robustness checks. Appendix F. Omitted confounders.
Adipokines Induce Catabolism of Newly Synthesized Matrix in Cartilage and Meniscus Tissues
Creators: name: Nishimuta, James F.
name: Levenston, Marc E.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Purpose: Altered synovial levels of various adipokines (factors secreted by fat as well as other tissues) have been associated with osteoarthritis onset and progression. However, the metabolic effects of adipokines on joint tissues, in particular the fibrocartilaginous menisci, are not well understood. This study investigated effects of several adipokines on release of recently synthesized extracellular matrix in bovine cartilage and meniscus tissue explants. Materials and Methods: After labeling newly synthesized proteins and sulfated glycosaminoglycans (sGAGs) with 3H-proline and 35S-sulfate, respectively, bovine cartilage and meniscus tissue explants were cultured for 6 days in basal medium (control) or media supplemented with adipokines (1 µg/ml of leptin, visfatin, adiponectin, or resistin) or 20ng/ml interleukin-1 (IL-1). Release of radiolabel and sGAG to the media during culture and the final explant water, DNA, sGAG and retained radiolabel were measured. MMP-2 and MMP-3 activities were assessed using gelatin and casein zymography, respectively. Results: Water and DNA contents were not significantly altered by any treatment. Visfatin, adiponectin, resistin and IL-1 stimulated sGAG release from meniscus whereas only IL-1 stimulated sGAG release from cartilage. Release of 3H and 35S were stimulated by resistin and IL-1 in meniscus but only by IL-1 in cartilage. Retained 3H was unaltered by any treatment, while retained 35S was reduced by visfatin, resistin, and IL-1 in meniscus and by only IL-1 in cartilage. Resistin and IL-1 elevated active MMP-2 and total MMP-3 in meniscus whereas cartilage MMP-3 activity was elevated by only IL-1. Conclusions: Resistin stimulated rapid and extensive catabolism of meniscus tissue, similar to IL-1, whereas adipokines minimally affected cartilage. Release of newly synthesized matrix was similar to overall release in both tissues. These observations provide further indications that meniscal tissue is more sensitive to proinflammatory factors than cartilage, and also suggest further study of resistin’s role in osteoarthritis.
Additional file 2: of Basic leucine zipper transcription factor SlbZIP1 mediates salt and drought stress tolerance in tomato
Creators: name: Zhu, Mingku
name: Meng, Xiaoqing
name: Cai, Jing
name: Li, Ge
name: Dong, Tingting
name: Li, Zongyun
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Figure S2. Multiple sequence alignment among SlbZIP1, SlbZIP07, SlbZIP10 and SlbZIP39 genes. (DOCX 570 kb)
Validation of a Parametric Finite Element Human Femur Model
Creators: name: Klein, Katelyn F.
name: Jingwen Hu
name: Reed, Matthew P.
name: Schneider, Lawrence W.
name: Rupp, Jonathan D.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Objective Finite element (FE) models with geometry and material properties that are parametric with subject descriptors, such as age and body shape/size, are being developed to incorporate population variability into crash simulations. However, the validation methods currently being used with these parametric models do not assess whether model predictions are reasonable in the space over which the model is intended to be used. This study presents a parametric model of the femur and applies a unique validation paradigm to this parametric femur model that characterizes whether model predictions reproduce experimentally observed trends. Methods FE models of male and female femurs with geometries that are parametric with age, femur length, and body mass index (BMI) were developed based on existing statistical models that predict femur geometry. These parametric FE femur models were validated by comparing responses from combined loading tests of femoral shafts to simulation results from FE models of the corresponding femoral shafts whose geometry was predicted using the associated age, femur length, and BMI. The effects of subject variables on model responses were also compared with trends in the experimental dataset by fitting similarly parameterized statistical models to both the results of the experimental data and the corresponding FE model results and then comparing fitted model coefficients for the experimental and predicted datasets. Results The average error in impact force at experimental failure for the parametric models was 5%. The coefficients of a statistical model fit to simulation data were within one standard error of the coefficients of a similarly parameterized model of the experimental data except for the age parameter, likely because material properties used in simulations were not varied with specimen age. In simulations to explore the effects of femur length, BMI, and age on impact response, only BMI significantly affected response for both men and women, with increasing BMI producing higher impact forces. Conclusions Impactor forces from simulations, on average, matched experimental values at the time of failure. In addition, the simulations were able to match the trends in the experimental dataset.
Additional file 1 of Selective hypermethylation is evident in small intestine samples from infants with necrotizing enterocolitis
Creators: name: Good, Misty
name: Chu, Tianjiao
name: Shaw, Patricia
name: Nolan, Lila S.
name: Wrobleski, Joseph
name: Castro, Carlos
name: Gong, Qingqing
name: DeWitt, Olivia
name: Finegold, David N.
name: Peters, David
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. Figure S1: Enrichment of genes in (A) “RhoGDI Signaling” (p = 5.05 × 10−6), (B) “FXR/RXR activation” (p = 5.35 × 10−6) and (C) “Hepatic Cholestasis” (9.06 × 10−5). Figure S2: Enrichment of genes in (A) “molecular mechanisms of cancer” (p = 9.82 × 10−9), (B) “GNRH signaling” (p = 6.51 × 10−6) and (C) “TGF-Signaling” (p = 6.56 × 10−6). Figure S3: Enrichment of genes in (A) “Adipogenesis pathway” (p = 9.41 × 10−6), (B) “CREB Signaling in Neurons” (p = 4.25 × 10−5) and (C) “1D-myo-inositol Hexakisphosphate Biosynthesis II” (p = 4.41 × 10−5)