title: ÐÐ°Ð»Ð¸Ð´Ð°ÑÐ¸Ñ Ð¼ÐµÑÐ¾Ð´Ð° ÑÐºÑÐ¿ÑÐµÑÑ-Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ Ð±Ð°ÐºÑÐµÑÐ¸Ð¹ "ÐºÑÐ°ÑÐ½Ð¾Ð³Ð¾" ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Validation of the method of express diagnostics of bacteria of the âredâ complex
Creators: name: ÐÐ°Ð¿Ð¾Ð½Ð¾Ð²Ð°, ÐÐ»Ð¸Ð·Ð°Ð²ÐµÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2023
Subjects: Ð¿ÑÐ¾ÑÐµÐ¾Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ°Ñ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ
Ð¼Ð¸ÐºÑÐ¾Ð±Ð¸Ð¾ÑÐ° ÑÐ¾ÑÐ¾Ð²Ð¾Ð¹ Ð¿Ð¾Ð»Ð¾ÑÑÐ¸
Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ñ Ð¿Ð°ÑÐ¾Ð´Ð¾Ð½ÑÐ°
Ð¿ÑÐ¾ÑÐµÐ°Ð·Ñ
Ð¿Ð°ÑÐ¾Ð´Ð¾Ð½ÑÐ¾Ð¿Ð°ÑÐ¾Ð³ÐµÐ½Ð½Ð°Ñ Ð¼Ð¸ÐºÑÐ¾ÑÐ»Ð¾ÑÐ°
Ð±Ð°ÐºÑÐµÑÐ¸Ð¸ "ÐºÑÐ°ÑÐ½Ð¾Ð³Ð¾" ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ°
ÑÐºÑÐ¿ÑÐµÑÑ-Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ°
Ð²Ð°Ð»Ð¸Ð´Ð°ÑÐ¸Ñ
Ð»Ð¸ÑÐ°Ð¹Ð½Ð¸ÐºÐ¸ ÑÐ¾Ð´Ð° Cladonia Ð¸ Parmelia
ÑÐ¿Ð¸ÑÑÐ¾Ð²ÑÐ¹ ÑÐºÑÑÑÐ°ÐºÑ
proteolitic activity
oral microbiota
periodontal diseases
proteases
parodontopathogenic microflora
bacteria of the "red" complex
express diagnostics
validation
liches of the genus Cladonia and Parmelia
alcoholic extract

description: Ð Ð¿ÑÐ¾ÑÐµÑÑÐµ ÑÐ°Ð±Ð¾ÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð»ÑÑ Ð¼Ð¸ÐºÑÐ¾Ð±Ð¸Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ¿ÐµÐºÑÑ ÑÐ¾ÑÐ¾Ð²Ð¾Ð¹ Ð¿Ð¾Ð»Ð¾ÑÑÐ¸, Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð»Ð¾ÑÑ ÑÐ¾Ð¿Ð¾ÑÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² Ð¼Ð¸ÐºÑÐ¾Ð±Ð¸Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¿ÐµÐºÑÑÐ° ÑÐ¾ÑÐ¾Ð²Ð¾Ð¹ Ð¿Ð¾Ð»Ð¾ÑÑÐ¸ (ÐÐ¦Ð -Ð°Ð½Ð°Ð»Ð¸Ð·) Ñ ÑÐºÑÐ¿ÑÐµÑÑ Ð¾ÑÐµÐ½ÐºÐ¾Ð¹ Ð¿ÑÐ¾ÑÐµÐ¾Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸. ÐÐ»Ñ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ Ð°Ð½ÑÐ¸Ð±Ð°ÐºÑÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾Ð¹ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð²Ð¾Ð´Ð½Ð¾-ÑÐ¿Ð¸ÑÑÐ¾Ð²ÑÑ ÑÐ°ÑÑÐ²Ð¾ÑÐ¾Ð² Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÐºÑÑÑÐ°ÐºÑÐ¾Ð² Ð»Ð¸ÑÐ°Ð¹Ð½Ð¸ÐºÐ¾Ð² Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ñ Ð¼Ð¸ÐºÑÐ¾Ð±Ð¸Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¸ Ð±Ð¸Ð¾ÑÐ¸Ð¼Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ñ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸ÐµÐ¼ Ð¼ÐµÑÐ¾Ð´Ð° Ð¿Ð¾ÑÐµÐ²Ð° Ð±Ð¸Ð¾Ð¿ÑÐ¾Ð±Ñ Ð¸Ð· Ð¿Ð°ÑÐ¾Ð´Ð¾Ð½ÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÐºÐ°ÑÐ¼Ð°Ð½Ð° Ð¾Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ° Ñ ÑÑÐ¾Ð½Ð¸ÑÐµÑÐºÐ¸Ð¼ Ð¿Ð°ÑÐ¾Ð´Ð¾Ð½ÑÐ¸ÑÐ¾Ð¼. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð±ÑÐ»Ð° Ð²Ð°Ð»Ð¸Ð´Ð¸ÑÐ¾Ð²Ð°Ð½Ð° Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ°, ÐºÐ¾ÑÐ¾ÑÐ°Ñ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÑÐµÑ Ð¿Ð¾ÑÑÐ´Ð¾Ðº Ð´ÐµÐ¹ÑÑÐ²Ð¸Ð¹ Ð¿ÑÐ¸ Ð¾ÑÐµÐ½ÐºÐµ Ð¿ÑÐ¾ÑÐµÐ¾Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¼Ð¸ÐºÑÐ¾Ð±Ð¸Ð¾ÑÑ ÑÐ¾ÑÐ¾Ð²Ð¾Ð¹ Ð¿Ð¾Ð»Ð¾ÑÑÐ¸ Ð½Ð° ÑÑÐ°Ð¿Ð°Ñ Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ, Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ Ð¸ Ð»ÐµÑÐµÐ½Ð¸Ñ ÑÑÐ¾Ð¼Ð°ÑÐ¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ñ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ð¹. Ð£ÑÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð¾, ÑÑÐ¾ 20 % Ð²Ð¾Ð´Ð½Ð¾-ÑÐ¿Ð¸ÑÑÐ¾Ð²ÑÐµ ÑÐ°ÑÑÐ²Ð¾ÑÑ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÐºÑÑÑÐ°ÐºÑÐ¾Ð² Ð»Ð¸ÑÐ°Ð¹Ð½Ð¸ÐºÐ¾Ð² Ð¿Ð¾ÐºÐ°Ð·Ð°Ð»Ð¸ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ ÑÑÐµÐ¿ÐµÐ½Ñ Ð°Ð½ÑÐ¸Ð¼Ð¸ÐºÑÐ¾Ð±Ð½Ð¾Ð¹ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¿Ð¾ Ð¾ÑÐ½Ð¾ÑÐµÐ½Ð¸Ñ Ðº Ð¼Ð¸ÐºÑÐ¾Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð¼Ð°Ð¼ Ð±Ð¸Ð¾Ð¿ÑÐ¾Ð±Ñ Ð¸Ð· Ð¿Ð°ÑÐ¾Ð´Ð¾Ð½ÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÐºÐ°ÑÐ¼Ð°Ð½Ð° Ð¾Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ° Ñ ÑÑÐ¾Ð½Ð¸ÑÐµÑÐºÐ¸Ð¼ Ð¿Ð°ÑÐ¾Ð´Ð¾Ð½ÑÐ¸ÑÐ¾Ð¼: Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð»Ð¸ÑÐ°Ð¹Ð½Ð¸ÐºÐ° Ð¡lÐ°dÐ¾niÐ° rÐ°ngifÐµrinÐ° â Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ Ð½Ð°Ð¸Ð±Ð¾Ð»ÐµÐµ Ð²ÑÑÐ°Ð¶ÐµÐ½Ð½Ð°Ñ, Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð»Ð¸ÑÐ°Ð¹Ð½Ð¸ÐºÐ° Parmelia vagans â Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ ÑÑÐµÐ´Ð½ÐµÐ¹ ÑÑÐµÐ¿ÐµÐ½Ð¸, Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÐ¼ÐµÑÐ¸ Ð»Ð¸ÑÐ°Ð¹Ð½Ð¸ÐºÐ¾Ð² Ð¡lÐ°dÐ¾niÐ° rÐ°ngifÐµrinÐ° Ð¸ Parmelia vagans â Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ Ð¼Ð¸Ð½Ð¸Ð¼Ð°Ð»ÑÐ½Ð¾Ð¹ ÑÑÐµÐ¿ÐµÐ½Ð¸. ÐÑÐ¸ Ð½Ð°Ð¿Ð¸ÑÐ°Ð½Ð¸Ð¸ ÑÐ°Ð±Ð¾ÑÑ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð»Ð¸ÑÑ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÐµ Ð±Ð°Ð·Ñ Ð´Ð°Ð½Ð½ÑÑ: Web of science, Elibrary, MDPI.
description: In the process of work, the microbiological spectrum of the oral cavity was studied, the results of the microbiological spectrum of the oral cavity (PCR analysis) were compared with an express assessment of proteolytic activity. To determine the antibacterial activity of water-alcohol solutions based on lichen extracts, microbiological and biochemical studies were carried out using the method of seeding a bioassay from a periodontal pocket from a patient with chronic periodontitis. As a result of the study, a methodology was validated that determines the procedure for assessing the proteolytic activity of the oral microbiota at the stages of planning, diagnosing and treating dental diseases. It was found that 20% water-alcohol solutions based on lichen extracts showed a different degree of antimicrobial activity against microorganisms of a bioassay from a periodontal pocket from a patient with chronic periodontitis: based on the lichen Ð¡ladonia rangiferina - the most pronounced activity, based on the lichen Parmelia vagans - medium activity degree, based on a mixture of lichens Ð¡ladonia rangiferina and Parmelia vagans â activity of the minimum degree. When writing the work, various databases were used, such as Web of science, ElibrarÑ, MDPI.