cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MOESM3 of Evaluation of divergent yeast genera for fermentation-associated stresses and identification of a robust sugarcane distillery waste isolate Saccharomyces cerevisiae NGY10 for lignocellulosic ethanol production in SHF and SSF
Creators: name: Pandey, Ajay
name: Mohit Kumar
name: Sonam Kumari
name: Kumari, Priya
name: Yusuf, Farnaz
name: Shaik Jakeer
name: Sumera Naz
name: Piyush Chandna
name: Ishita Bhatnagar
name: Gaur, Naseem
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 4. Fermentation profile at 30 °C, 40 °C and 42 °C in SD media containing 50.0 g/l pure xylose in 24 h.
Additional file 5 of Prevalence of chronic cough in China: a systematic review and meta-analysis
Creators: name: Liang, Hanwen
name: Ye, Weiyan
name: Wang, Zhufeng
name: Liang, Jingyi
name: Yi, Fang
name: Jiang, Mei
name: Lai, Kefang
Publisher: name: figshare
Year: 2022
Subjects: Biotechnology
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 5. Methodology of studies included in the meta-analysis.
Additional file 1: of Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain
Creators: name: Ozge Yildiz
name: Downes, Gerald
name: Sagerstrรถm, Charles
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: Sequences of oligos used to generate CRISPR guide RNAs. Detailed features of the oligos used as templates for each guide RNA. (DOCX 13 kb)
Transitioning from oral risperidone or paliperidone to once-monthly paliperidone palmitate: a real-world analysis among veterans’ health administration patients with schizophrenia who have had at least one prior hospitalization
Creators: name: El Khoury, Antoine
name: Patel, Charmi
name: Huang, Ahong
name: Wang, Li
name: Bashyal, Richa
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Mental Health

description: Objective: To address gaps in the literature on healthcare resource utilization (HRU) and costs among patients with schizophrenia and prior hospitalization who transition from oral risperidone or paliperidone (oral ris/pali) to once-monthly paliperidone palmitate (PP1M) in a real-world setting by comparing treatment patterns, HRU, and costs 12-months pre- and post-transition to PP1M among Veterans Health Administration (VHA) patients affected by schizophrenia who have had ≥1 hospitalization. Methods: VHA patients with schizophrenia (aged ≥18 years) who initiated oral ris/pali, had ≥1 all-cause inpatient stay and transitioned to PP1M from January 2015 through March 2017 were included from the VHA database. The first transition date to PP1M was identified as the index date. Patients were required to have continuous health plan eligibility for 12 months pre- and post-PP1M. Outcomes were compared using the Wilcoxon signed-rank and McNemar’s test, as appropriate. Results: The study included 319 patients (mean [SD] age: 51.6 [4.2] years) during 12-months of baseline and follow-up. During pre-PP1M transition, 7.2% of the patients were adherent (proportion of days covered [PDC] ≥ 80%) to oral ris/pali. Post-PP1M transition, 27.6% of the patients were adherent to PP1M. Comparison of HRU outcomes from the pre- to post-PP1M transition revealed significantly lower all-cause inpatient stays (3.5 vs 1.4, p < 0.0001) and shorter inpatient length of stay (43.4 vs 18.3 days, p < 0.0001). Similar trends were seen for mental health and schizophrenia-related HRU. Cost outcome comparison indicated significantly lower all-cause inpatient costs ($64,702 vs $24,147, p < 0.0001), total medical costs ($87,917 vs $56,947, p < 0.0001), and total costs ($91,181 vs $69,106, p < 0.0001). A similar trend was observed for mental health and schizophrenia-related costs. Conclusions: Transitioning from oral ris/pali to PP1M may significantly improve HRU and provide potential cost savings in VHA patients with schizophrenia and ≥1 prior hospitalization.
Polymers in Fluid Flows
Creators: name: Benzi, Roberto
name: Ching, Emily S. C.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: The interaction of flexible polymers with fluid flows leads to a number of intriguing phenomena observed in laboratory experiments, namely drag reduction, elastic turbulence and heat transport modification in natural convection, and is one of the most challenging subjects in soft matter physics. In this paper we review our present knowledge on the subject. Our present knowledge is mostly based on direct numerical simulations performed in the last twenty years, which have successfully explained, at least qualitatively, most of the experimental results. Our goal is to disentangle as much as possible the basic mechanisms acting in the system in order to capture the basic features underlying different theoretical approaches and explanations.
Late Complications of High-Dose (≥66 Gy) Thoracic Conformal Radiation Therapy in Combined Modality Trials in Unresectable Stage III Non-small Cell Lung Cancer
Creators: name: Stinchcombe, Thomas E.
name: Rosenman, Julian G.
name: Hayes, D Neil
name: Rivera, M Patricia
name: Lee, Carrie B.
name: Morris, David E.
name: Moore, Dominic T.
name: Socinski, Mark A.
name: Halle, Jan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BACKGROUND: Combined modality treatment is the standard of care for patients (pts) with unresectable stage III non-small cell lung cancer. Dose escalation of radiotherapy is one strategy used to improve locoregional control and survival, but it increases the risk of both early and late treatment related toxicities.

METHODS: From May 1996 to August 2004, a total of 112 stage III non-small cell lung cancer pts were treated on 4 phase I/II or phase II trials to assess the safety and feasibility of high-dose (60-90 Gy) thoracic conformal radiotherapy. Patients who received >/=66 Gy (n = 88) were included in an analysis of late complications. Late complications were defined as complications that developed or persisted >/=90 days postradiotherapy. The classic lung toxicities of radiation pneumonitis and fibrosis were not included in this analysis.

RESULTS: Of the 88 patients included in this analysis of late complications, 21 patients (24%) developed a late complication and a total of 28 late complications were observed. The late complications were: pulmonary (n = 5; bronchial stenosis [n = 3] and fatal pulmonary hemoptysis [n = 2]), esophageal (n = 6), cardiac (n = 9), osseous (n = 6), and second primary tumor (n = 2). The median survival for all patients enrolled on the 4 trials (with 95% confidence interval [CI]) was 24.7 months (18.1-30.4 months), and the 5-year overall survival (with 95% CI) was 24% (16-32%). Data to assess for radiographic evidence of local progression were available for 99 patients, and the rate of local progression was 43% (95% CI 34-53%).

CONCLUSIONS: High-dose thoracic conformal radiotherapy is feasible and results in promising survival outcomes. Late complications occur in a minority of patients.
Towards Value-Sensitive Learning Analytics Design
Creators: name: Chen, Bodong
name: Zhu, Haiyi
Publisher: name: arXiv
Year: 2018
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: To support ethical considerations and system integrity in learning analytics, this paper introduces two cases of applying the Value Sensitive Design methodology to learning analytics design. The first study applied two methods of Value Sensitive Design, namely stakeholder analysis and value analysis, to a conceptual investigation of an existing learning analytics tool. This investigation uncovered a number of values and value tensions, leading to design trade-offs to be considered in future tool refinements. The second study holistically applied Value Sensitive Design to the design of a recommendation system for the Wikipedia WikiProjects. To proactively consider values among stakeholders, we derived a multi-stage design process that included literature analysis, empirical investigations, prototype development, community engagement, iterative testing and refinement, and continuous evaluation. By reporting on these two cases, this paper responds to a need of practical means to support ethical considerations and human values in learning analytics systems. These two cases demonstrate that Value Sensitive Design could be a viable approach for balancing a wide range of human values, which tend to encompass and surpass ethical issues, in learning analytics design.
description: The 9th International Learning Analytics & Knowledge Conference (LAK19)
Field-induced Ordering in Critical Antiferromagnets
Creators: name: de Queiroz, S. L. A.
name: Paiva, Thereza
name: Martins, Jorge S. de Sá
name: Santos, Raimundo R. dos
Publisher: name: arXiv
Year: 1998
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Transfer-matrix scaling methods have been used to study critical properties of field-induced phase transitions of two distinct two-dimensional antiferromagnets with discrete-symmetry order parameters: triangular-lattice Ising systems (TIAF) and the square-lattice three-state Potts model (SPAF-3). Our main findings are summarised as follows. For TIAF, we have shown that the critical line leaves the zero-temperature, zero -field fixed point at a finite angle. Our best estimate of the slope at the origin is $(dT_c/dH)_{T=H=0} = 4.74 \pm 0.15$. For SPAF-3 we provided evidence that the zero-field correlation length diverges as $ξ(T \to 0, H=0) \simeq \exp (a/T^{x})$, with $x=1.08 \pm 0.13$, through analysis of the critical curve at $H \neq 0$ plus crossover arguments. For SPAF-3 we have also ascertained that the conformal anomaly and decay-of-correlations exponent behave as: (a) H=0: $c=1, η=1/3$; (b) $H \neq 0: c=1/2, η=1/4$.
description: RevTex, 7 pages, 4 eps figures, to be published in Phys. Rev. E
Mechanical properties of boron phosphides
Creators: name: Solozhenko, Vladimir L.
name: Bushlya, Volodymyr
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Microstructure and mechanical properties of bulk polycristalline boron phosphides (cubic BP and rhombohedral B12P2) have been studied by scanning electron microscopy and micro- and nanoindentation. The obtained data on hardness, elastic properties and fracture toughness clearly indicate that both phosphides belong to a family of hard phases and can be considered as prospective binders for diamond and cubic boron nitride.
description: arXiv admin note: substantial text overlap with arXiv:1710.01700
Risk of Recurrence of Resected Stage I Non-small Cell Lung Cancer in Elderly Patients as Compared with Younger Patients
Creators: name: Subramanian, Janakiraman
name: Viswanathan, Avinash
name: Gao, Feng
name: Miller, C Ryan
name: Patterson, Alexander G.
name: Govindan, Ramaswamy
name: Goodgame, Boone
name: Meyers, Bryan F.
name: Zoole, Jennifer
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Half of all patients with non-small cell lung cancer (NSCLC) are 70 years or older at the time of diagnosis. Surgery is an option for fit elderly patients with early stage disease, but rates of disease recurrence after surgical resection are not well described. We report the outcomes in elderly patients (70 years or older) with stage I NSCLC after surgical resection.We conducted a retrospective study of patients diagnosed with stage I NSCLC after surgical resection at Washington University School of Medicine-Alvin J. Siteman Cancer Center from 1990 to 2000. Demographic, pathologic, treatment, and follow-up data were collected. Recurrence rates and overall survival were calculated by the Kaplan-Meier method. Multivariate Cox proportional hazards models were used to detect associations between potential prognostic factors and survival and recurrence.Of the 715 patients with stage I NSCLC, 286 were 70 years or older at diagnosis. In this elderly cohort, the median age was 74 years (range, 70–89 years) and 140 of them were women (49%). Lobectomy was performed in 237 patients (83%) whereas 43 patients (15%) had a wedge or segmental resection, and six patients (2%) underwent pneumonectomy. Clinical and pathologic characteristics were not statistically different between the elderly and younger cohorts, with the exception that older patients were more likely to be white (90% versus 80%, p = 0.0003) and less likely to be smokers (88% versus 95%, p = 0.019) compared with the younger cohort. With a median follow-up of 4.6 years, the overall 5-year survival rate was 52% with a 5-year recurrence rate of 24%. In comparison, the patients younger than 70 years had a 5-year survival rate of 67% (p < 0.001) and a 5-year recurrence rate of 24%.Although overall survival was worse in elderly patients, estimated disease recurrence rates after resection were identical.
Infodemic During a Pandemic: Media Information Literacy and Other Communication Factors Related to (Mis)Information Sharing on Covid 19 Among Graduate Students in an Open University
Creators: name: Lleva, Yrelle Mae
Publisher: name: Zenodo
Year: 2022
Subjects: Theory of Reasoned Action, fake news sharing, Covid 19, misinformation, media, and information literacy

description: INFODEMIC DURING A PANDEMIC: MEDIA INFORMATION LITERACY AND OTHER COMMUNICATION FACTORS RELATED TO (MIS)INFORMATION SHARING ON COVID 19 AMONG GRADUATE STUDENTS IN AN OPEN UNIVERSITY

Underpinned by the Theory of Reasoned Action (TRA) by Ajzen and Fishbein, an online survey was conducted from October 25, 2021, to February 28, 2022, through Google Forms with 107 online students. Data were analyzed using descriptive statistics and Spearman’s correlation for the relationship of variables. The prevalent social media used by the respondents is Facebook, mostly for 6-15 hours a day. They used social media to seek information/news, entertain themselves, share information/news, gain knowledge, and also pass time. While the students perceive themselves to have high online skills, favorable beliefs and attitude toward information verification, high media literacy, perceived selfefficacy in verifying information, and likely intention to not share fake information, they have actually shared fake information on Covid 19 on social media. In the past months, they have shared the news on social media without verifying the source, and they have ‘very frequently’ been told by their networks that they have shared fake news. They have shared fake news because it was easy to retrieve and share information online, they were motivated to influence others’ opinions, they desired to establish connections, they were dealing with social media fatigue, and they wanted to join the bandwagon. Behavior of sharing misinformation on Covid 19 was correlated with media and information literacy such as the literacy in access and retrieval and the literacy in evaluation and understanding. Only the media literacy variables are correlated with behavior. Hence, overall, media and information literacy can be considered to be associated with fake news sharing on social media. To prevent or minimize the spread of misinformation on Covid 19, these should be strengthened: media information literacy, education on fake news sharing, and media messages that will educate people on the accuracy of information.
Treatment Paradigms for Advanced Stage Non-small Cell Lung Cancer in the Era of Multiple Lines of Therapy
Creators: name: Socinski, Mark A.
name: Stinchcombe, Thomas E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Abstract:: The duration of first-line and the timing of second-line therapy for advanced non-small cell lung cancer has been an area of recent investigation. Five trials have been performed that have investigated shorter (3–4 cycles) versus longer duration of platinum-based therapy; four trials revealed an equivalent overall survival with the shorter duration of therapy, and one trial revealed superior survival with the longer duration of therapy. The toxicity and quality of life data has either been equivalent or favored the shorter duration of therapy. Two trials have investigated the timing of a second-line therapy after completion of four cycles of platinum-based therapy versus the standard treatment paradigm of initiating second-line therapy upon disease progression. Both of these trials have revealed a statistically significant improvement in the progression-free survival, and a trend towards improved survival for the earlier use of second-line therapy. Only 50 to 60% of patients on the standard treatment arm initiated second-line therapy, and the promising results observed are most likely related to the fact that a higher percentage of patients received second-line therapy on the experimental arm. Several trials have investigated maintenance chemotherapy, and these trials have not revealed a survival benefit probably due to the fact that many patients experience disease progression or unacceptable toxicity during the initial or maintenance therapy. The addition of a targeted agent (bevacizumab or cetuximab) to the initial chemotherapy and the continuation of the targeted agent after completion of the chemotherapy have yielded superior overall survival in comparison to chemotherapy alone. The incremental benefit of the maintenance therapy with the targeted agent is unknown.
Additional file 12: of Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain
Creators: name: Ozge Yildiz
name: Downes, Gerald
name: Sagerstrรถm, Charles
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Generation of germ line nkx6.1 mutants. a. Schematic showing genomic sequence of nkx6.1 with the homeodomain indicated in green. The CRISPR target sequence is shown in red with the AvaII restriction site bracketed and the black arrow indicating the AvaII cut site. b. Identification of functional guide RNAs. sgRNA and cas9 mRNA was injected into 1-cell stage embryos. Injected embryos were raised to 24hpf and AvaII digestion of PCR amplicons from pooled embryos was used to identify CRISPR-induced mutations (black arrow). c. Identification of individual F0 founders. sgRNA/cas9 injected embryos were raised to adulthood and crossed to wildtype fish. AvaII digests of PCR amplicons from pools of embryos was used to identify F0 mosaic founders (black arrow). d. Identification of F1 animals. Adult F0 mosaic founders were out-crossed to wildtype fish and the F1 offspring raised to adulthood. AvaII digests of PCR amplicons from fin clip genomic DNA was used to identify heterozygous F1 animals. e. Sequencing of F1 genomic DNA revealed the transmission of two mutant alleles (um321, um322). um321 carries a 23 base pair deletion (black dashes) while um322 carries a 1 base pair insertion (green) and 3 base pair substitutions (blue). The CRISPR target sequence is shown in red. f. Predicted amino acid sequence of mutant alleles. The um320 and um321 peptides share their first 44 amino acids with the wildtype sequence before going out of frame and terminating at a premature stop codon N-terminal to the conserved homeodomain. g. Quantification of the size (along the dorsoventral axis) of the nkx6.1 expression domain in prdm12b MO-injected embryos (data from Fig. 8). (PDF 651 kb)
Incommensurate $2k_F$ density wave quantum criticality in two dimensional metals
Creators: name: Halbinger, Johannes
name: Pimenov, Dimitri
name: Punk, Matthias
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We revisit the problem of two dimensional metals in the vicinity of a quantum phase transition to incommensurate $\mathbf{Q}=2k_F$ charge density wave order, where the order parameter wave vector $\mathbf{Q}$ connects two hot spots on the Fermi surface with parallel tangents. Earlier theoretical works argued that such critical points are potentially unstable, if the Fermi surface at the hot spots is not sufficiently flat. Here we perform a controlled, perturbative renormalization group analysis and find a stable fixed point corresponding to a continuous quantum phase transition, which exhibits a strong dynamical nesting of the Fermi surface at the hot spots. We derive scaling forms of correlation functions at the critical point and discuss potential implications for experiments with transition metal dichalcogenides and rare-earth tellurides.
description: 11 pages, 3 figures; journal version
Additional file 1: of Characterization of the mitochondrial genome of the MAX1 type of cytoplasmic male-sterile sunflower
Creators: name: Makarenko, Maksim
name: Usatov, Alexander
name: Tatarinova, Tatiana
name: Azarin, Kirill
name: Logacheva, Maria
name: Gavrilova, Vera
name: Horn, Renate
Publisher: name: figshare
Year: 2019
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy
subject: Plant Biology
subject: 60506 Virology

description: The primers sets used for HA89 (MAX1) genome reorganizations validation and gene expression analysis. *- has been also used in previous study (Makarenko et al., 2018). (DOCX 13 kb)
Critical properties of Bose-glass superconductors
Creators: name: Lidmar, Jack
name: Wallin, Mats
Publisher: name: arXiv
Year: 1998
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We study vortex lines in high-temperature superconductors with columnar defects produced by heavy ion irradiation. We reconsider scaling theory for the Bose glass transition with tilted magnetic fields, and propose, e.g., a new scaling form for the shape of the Bose glass phase boundary, which is relevant for experiments. We also consider Monte Carlo simulations for a vortex model with a screened interaction. Critical exponents are determined from scaling analysis of Monte Carlo data for current-voltage characteristics and other quantities. The dynamic critical exponent is found to be z = 4.6 +/- 0.3.
description: 7 pages EuroTeX, 4 eps figures. Published version
A Comparison of White and African American Outcomes from a Three-Arm, Randomized, Phase III Multicenter Trial of Advanced or Metastatic Non-small Cell Lung Cancer
Creators: name: Catalano, Robert B.
name: Ansari, Rafat H.
name: Socinski, Mark A.
name: Ribeiro, Maria-Jose
name: Obasaju, Coleman K.
name: Comis, Robert L.
name: Marinucci, Donna M.
name: Treat, Joseph
name: Chen, Ruqin
name: Liles, Darla K.
name: Monberg, Matthew J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: PURPOSE: To investigate the effect of race on the efficacy and safety of standard chemotherapy doublet regimens in African American patients, we conducted a subgroup analysis of a phase III randomized trial.

PATIENTS AND METHODS: Chemonaïve patients with a performance status of 0 or 1 and stage IIIB or IV non-small cell lung cancer were randomized to arm A: gemcitabine 1000 mg/m2 on days 1 and 8 plus carboplatin area under the curve 5.5 on day 1; arm B: the same schedule of gemcitabine plus paclitaxel 200 mg/m2 on day 1; or arm C: paclitaxel 225 mg/m2 on day 1 plus carboplatin area under the curve 6.0 on day 1. Cycles were repeated every 21 days up to 6. A site selection tool identified institutions with potential to recruit a minority population. Outcome and toxicity data of white and African American patients were compared.

RESULTS: Of 1135 total patients, 972 were white (85.6%) and 138 were African American (12.2%). Median survival was 8.3 months for white patients (95% confidence interval [CI]: 7.7-9.3) and 9.1 months for African American patients (95% CI: 8.2-11.1). Response rates were 29.1 and 29.0%, respectively. Rates of grade 3 or 4 toxicities were comparable. Among African Americans, median survival was 7.2 months (95% CI: 5.1-10.1) for gemcitabine-carboplatin (n = 47), 10.5 months (95% CI: 7.1-15.4) for gemcitabine-paclitaxel (n = 42), and 10.2 months (95% CI: 8.5-13.2) for paclitaxel-carboplatin (n = 49).

CONCLUSION: Whites and African Americans had similar outcomes, although there was some variability in survival among African Americans across the three treatment groups.
True Superconductivity in a 2D "Superconducting-Insulating" System
Creators: name: Mason, Nadya
name: Kapitulnik, Aharon
Publisher: name: arXiv
Year: 2000
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present results on disordered amorphous films which are expected to undergo a field-tuned Superconductor-Insulator Transition. Based on low-field data and I-V characteristics, we find evidence of a low temperature Metal-to-Superconductor transition. This transition is characterized by hysteretic magnetoresistance and discontinuities in the I-V curves. The metallic phase just above the transition is different from the "Fermi Metal" before superconductivity sets in.
description: 3 pages, 4 figures
Outcomes Associated with Brain Metastases in a Three-Arm Phase III Trial of Gemcitabine-Containing Regimens Versus Paclitaxel Plus Carboplatin for Advanced Non-small Cell Lung Cancer
Creators: name: Treat, Joseph
name: Socinski, Mark A.
name: Ansari, Rafat H.
name: Obasaju, Coleman K.
name: Chen, Ruqin
name: Edelman, Martin J.
name: Monberg, Matthew J.
name: Belani, Chandra P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: BACKGROUND: Brain metastases (BMs) are a common complication of non-small cell lung cancer (NSCLC). Because of historical data indicating a poor prognosis for patients with BM, few randomized phase III studies of advanced NSCLC have included patients with BM at presentation. Because the potential benefits of systemic therapy in patients with BM are uncertain, we analyzed data from a recent phase III study.

METHODS: One thousand one hundred thirty-five chemonaïve patients with stage IIIB/IV NSCLC were randomized to receive gemcitabine/carboplatin, gemcitabine/paclitaxel, or paclitaxel/carboplatin. Stratification was based on presence or absence of BM, stage, and baseline weight loss. Patients with BM were required to be clinically stable after treatment with radiotherapy or surgery before entry. Results were retrospectively analyzed by presence or absence of BM at study entry.

RESULTS: Rate of BM was 17.1% overall. The response rate was 28.9% for patients with BM (n = 194) versus 29.1% without BM (n = 941). Time to progression was 4.3 months with BM and 4.6 months without BM (p = 0.03). Median survival was 7.7 months (95% confidence interval: 6.7-9.3) among patients with BM (n = 194) and 8.6 months (95% confidence interval: 7.9-9.5) for patients without BM (n = 941), p = 0.09. Rates of hematologic adverse events were not different among patients with and without BM.

CONCLUSIONS: There were no significant differences in response, survival, or hematologic toxicity for patients with or without BM; however, patients with BM had a small but significantly shorter time to progression. Nonprogressing patients with treated BM are appropriate candidates for systemic therapy and entry into clinical trials.
Superconducting Coherence and the Helicity Modulus in Vortex Line Models
Creators: name: Lidmar, Jack
name: Wallin, Mats
Publisher: name: arXiv
Year: 1998
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We show how commonly used models for vortex lines in three dimensional superconductors can be modified to include k=0 excitations. We construct a formula for the k=0 helicity modulus in terms of fluctuations in the projected area of vortex loops. This gives a convenient criterion for the presence of superconducting coherence. We also present Monte Carlo simulations of a continuum vortex line model for the melting of the Abrikosov vortex lattice in pure YBCO.
description: 4 pages RevTeX, 2 eps figures included using epsf
Equipartition and Virial theorems in a nonextensive optimal Lagrange multipliers scenario
Creators: name: Martinez, S.
name: Pennini, F.
name: Plastino, A.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We revisit some topics of classical thermostatistics from the perspective of the nonextensive optimal Lagrange multipliers (OLM), a recently introduced technique for dealing with the maximization of Tsallis' information measure. It is shown that Equipartition and Virial theorems can be reproduced by Tsallis' nonextensive formalism independently of the value of the nonextensivity index.
description: 13 pages, no figures
Pemetrexed with or without Matuzumab as Second-Line Treatment for Patients with Stage IIIB/IV Non-small Cell Lung Cancer
Creators: name: Sebastian, Martin
name: von Pawel, Joachim
name: Pfeifer, Wolfgang
name: Saleh, Mansoor
name: Ansari, Rafat H.
name: Kloecker, Goetz H.
name: Pirker, Robert
name: Schiller, Joan H.
name: McCroskey, Robert D.
name: Marsland, Thomas A.
name: Beadman, Claire
name: Socinski, Mark A.
name: Thomas, Michael
name: Kurek, Raffael
name: Schütt, Philipp
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: INTRODUCTION: This randomized phase II study investigated pemetrexed in combination with the epidermal growth factor receptor (EGFR)-targeting monoclonal antibody matuzumab compared with pemetrexed alone as second-line therapy for patients with advanced non-small cell lung cancer.

METHODS: Patients received pemetrexed 500 mg/m every 3 weeks either alone (n = 50) or in combination with matuzumab at either 800 mg weekly (n = 51) or 1600 mg every 3 weeks (n = 47). The primary end point was objective response, as assessed by an independent review committee.

RESULTS: Tumor EGFR expression was detected in 87% of randomized patients. The objective response rate for the pooled matuzumab-treated arms was 11% compared with 5% for pemetrexed alone (p = 0.332). Apart from one patient in the pemetrexed alone group, all responses occurred in patients whose tumors expressed EGFR. The objective response rate for patients receiving weekly matuzumab was 16% compared with 2% for those receiving matuzumab every 3 weeks. There was also a trend for improved overall survival in patients receiving matuzumab weekly versus every 3 weeks (12.4 months versus 5.9 months, respectively, versus 7.9 months for pemetrexed alone). The combination of pemetrexed and matuzumab demonstrated an acceptable safety profile, with the most common grade 3/4 adverse event being neutropenia.

CONCLUSION: Although the analysis on the pooled matuzumab-treated arms did not demonstrate a statistically significant improvement in objective response for the addition of matuzumab to pemetrexed compared with pemetrexed alone, the trends for improvement in objective response and overall survival for pemetrexed plus weekly matuzumab compared with pemetrexed alone warrant confirmation in additional clinical trials.
Fermiology of a 1D heavy electron metal
Creators: name: Groeber, C.
name: Eder, R.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present a Quantum Monte Carlo (QMC) study of the 1D Kondo lattice at non-integer filling, i.e. a one-dimensional version of a heavy electron metal. For this special system the minus-sign problem turns out to be strongly reduced, which allows QMC simulations for temperatures as low as 1% of the conduction electron bandwidth. The single particle Green's function shows and intricate network of low-energy bands at low temperature, with a Fermi surface volume that comprises both c and f-electrons. As temperature increases the system evolves through two distinct crossover temperatures into a very simple band structure with one free c-electron band and a disconnected upper and lower Hubbard band for f-electrons. The f-electrons thus `drop out' of the Fermi surface volume as temperature increases.
description: RevTex-file, 4 PRB pages with 4 eps figures. Hardcopies of figures (or the entire manuscript) can be obtained by e-mail request to: eder@physik.uni-wuerzburg.de
ПОНИМАНИЕ И УСВОЕНИЕ ПАДЕЖНОЙ СИСТЕМЫ РУССКОГО ЯЗЫКА, ОШИБКИ ИНОСТРАННЫХ СТУДЕНТОВ В СКЛОНЕНИИ.
Creators: name: Якубова, Мунаввар
Publisher: name: Zenodo
Year: 2024

description: Изучение падежной системы русского языка иностранными студентами является ключевым этапом для освоения этого сложного и гибкого языка. Русский язык имеет шесть падежей, каждый из которых отражает различные отношения между словами в предложении. В некоторых языках, особенно англоязычных, падежная система отсутствует или имеет уже упрощенную форму, что может создавать сложности при освоении падежей в русском. Данная работа предназначена для обсуждения методов, идей и ресурсов, которые могут помочь иностранным студентам усвоить падежную систему русского языка с большей уверенностью
Additional file 1 of Risk of bias in observational studies using routinely collected data of comparative effectiveness research: a meta-research study
Creators: name: Nguyen, Van Thu
name: Engleton, Mishelle
name: Davison, Mauricia
name: Ravaud, Philippe
name: Porcher, Raphael
name: Boutron, Isabelle
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Virology

description: Additional file 1: Table S1. Search strategy. Table S2. Eligibility criteria. Table S3. Data extraction form. Table S4. Data Extraction Form Explanation.
BO'LAJAK INFORMATIKA FANI O'QITUVSHILARINING TASHKILIY-PEDAGOGIK KOMPETENTLIGINI  ANIQLASHGA OID TAJRIBA SINOV ISHLARI MAZMUNI
Creators: name: Muxlisov, Sodiqjon
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqoladi oliy ta’lim tizimida bo‘lajak informatika o‘qituvshisining kasbiy kompetentligiga qo‘yiladigan zamonaviy talablar, jamiyat va ta’limni axborotlashtirish sharoitida kasbiy faoliyatning o‘ziga xos xususiyatlarini o‘rganish, tadqiq yetishga bo‘lgan ye’tibor, bo‘lajak informatika o‘qituvshisining tashkiliy va pedagogik kompetentligini oshirishga tayyorligi va mavzuga bo‘yicha olib borilgan tajriba sinov ishlarining mazmuniniga oid ma’lumotlar keltirilgan.
Analyticity Property of Scattering Amplitude in Theories with Compactified Space Dimensions
Creators: name: Maharana, Jnanadeva
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider a massive, neutral, scalar field theory of mass $m_0$ in a five dimensional flat spacetime. Subsequently, one spatial dimension is compactified on a circle, $S^1$, ofradius $R$. The resulting theory is defined in the manifold, $R^{3,1}\otimes S^1$. The mass spectrum is a state of lowest mass, $m_0$, and a tower of massive Kaluza-Klein states. The analyticity property of the elastic scattering amplitude is investigated in the Lehmann-Symanzik-Zimmermann (LSZ) formulation of this theory. In the context of nonrelativistic potential scattering, for the $R^3\otimes S^1$ spatial geometry, it was shown that the forward scattering amplitude does not satisfy analyticity properties in some cases for a class of potentials. If the same result is valid in relativistic quantum field theory then the consequences will be far reaching. We show that the forward elastic scattering amplitude of the theory, in the LSZ axiomatic approach, satisfies forward dispersion relations. The importance of the unitarity constraint on the S-matrix, is exhibited in displaying the properties of the absorptive part of the amplitude.
description: 36 pages; no figures
Randomized, Phase II Trial of Pemetrexed and Carboplatin with or without Enzastaurin versus Docetaxel and Carboplatin as First-Line Treatment of Patients with Stage IIIB/IV Non-small Cell Lung Cancer
Creators: name: Jotte, Robert
name: Stinchcombe, Thomas
name: Periman, Phillip O.
name: Couch, Linda S.
name: Treat, Joseph
name: Weissman, Charles H.
name: Socinski, Mark A.
name: Wang, Yunfei
name: Choksi, Janak K.
name: Peng, Guangbin
name: Rousey, Steven R.
name: Raju, Robert N.
name: Barrera, David
name: Obasaju, Coleman K.
name: Pritchard, Sharon
name: Asmar, Lina
name: Bromund, Jane
name: Schlossberg, Howard R.
name: Kocs, Darren M.
name: Patt, Debra A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Enzastaurin is an oral serine/threonine kinase inhibitor that targets protein kinase C-beta (PKC-β) and the phosphatidylinositol-3-kinase/AKT pathway. This trial assessed pemetrexed-carboplatin ± enzastaurin to docetaxel-carboplatin in advanced non-small cell lung cancer.Patients with stage IIIB (with pleural effusion) or IV non-small cell lung cancer and performance status 0 or 1 were randomized to one of the three arms: (A) pemetrexed 500 mg/m and carboplatin area under the curve 6 once every 3 weeks for up to 6 cycles with a loading dose of enzastaurin 1125 or 1200 mg followed by 500 mg daily until disease progression, (B) the same regimen of pemetrexed-carboplatin without enzastaurin, or (C) docetaxel 75 mg/m and carboplatin area under the curve 6 once every 3 weeks for up to six cycles. The primary end point was time to disease progression (TTP).Between March 2006 and May 2008, 218 patients were randomized. Median TTP was 4.6 months for pemetrexed-carboplatin-enzastaurin, 6.0 months for pemetrexed-carboplatin, and 4.1 months for docetaxel-carboplatin (differences not significant). Median survival was 7.2 months for pemetrexed-carboplatin-enzastaurin, 12.7 months for pemetrexed-carboplatin, and 9.2 months for docetaxel-carboplatin (log-rank = 0.05). Compared with the other arms, docetaxel-carboplatin was associated with lower rates of grade 3 thrombocytopenia and anemia but a higher rate of grade 3 or 4 febrile neutropenia.There was no difference in TTP between the three arms, but survival was longer with pemetrexed-carboplatin compared with docetaxel-carboplatin. Enzastaurin did not add to the activity of pemetrexed-carboplatin.
Hydrocassis metasternalis Ji & Schodl 1995
Creators: name: Jia, Fenglong
name: Zhao, Shuang
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Hydrophilidae
Hydrocassis
Hydrocassis metasternalis

description: Hydrocassis metasternalis Ji & Schödl, 1995
(Fig. 15)
 Material examined. CHINA: YUNNAN: 1 J (IZCAS): Lushui, Pianma, 2300 m, 30.v.1981, Subai Liao lgt.
 Distribution. China (Yunnan: Baoshan, Gaoligongshan, Lushui), Thailand (SCHÖDL & JI 1995, SCHÖDL 2000).
description: Published as part of Jia, Fenglong & Zhao, Shuang, 2013, Descriptions of eleven Opatrini pupae (Coleoptera, Tenebrionidae) from China, pp. 127-139 in Acta Entomologica Musei Nationalis Pragae 53 (1) on page 134, DOI: 10.5281/zenodo.5740471
Timing of Local and Distant Failure in Resected Lung Cancer: Implications for Reported Rates of Local Failure
Creators: name: Kelsey, Chris R.
name: Kim, Dong W.
name: Marks, Lawrence B.
name: Hollis, Donna
name: Hubbs, Jessica L.
name: Boyd, Jessamy A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: INTRODUCTION: Most adjuvant lung cancer trials only report first sites of failure. The relative timing of local (i.e., local/regional) versus distant recurrence after surgery could potentially affect reported rates of local failure. We assessed this phenomenon in a large group of patients undergoing surgery for early-stage lung cancer.

METHODS: This institutional review board-approved retrospective study identified all patients who underwent surgery at Duke University Medical Center for pathologic stages I to II non-small cell lung cancer between 1995 and 2005. Medical records and pertinent radiographs were reviewed to assess for local and distant sites of recurrence. Both first and subsequent failures were examined. The time interval between surgery and date of local and/or distant failure was compared using the Mann-Whitney U test.

RESULTS: Of 975 patients undergoing surgery, 250 patients developed recurrent disease (43 local only, 110 distant only, and 97 both). The median time from surgery to local failure was 13.9 months (range, 1-79). The median time to distant failure was 12.5 months (range, 1-79 months). These were not significantly different (p = 0.34). Among 97 patients who experienced both local and distant failure, 72 (74%) failed at both sites simultaneously, 19 (20%) failed at local sites first, and 6 (6%) failed at distant sites first.

CONCLUSIONS: The time interval from surgery to either local or distant failure is not significantly different. Patterns of failure analyses in which only first sites of failure are scored will underestimate the frequency of local recurrence. Nevertheless, the magnitude of this error is expected to be small.
Additional file 1 of Microplastics in surface water and sediments of Chongming Island in the Yangtze Estuary, China
Creators: name: Li, Yubo
name: Lu, Zhibo
name: Zheng, Hongyuan
name: Wang, Juan
name: Chen, Cheng
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1: Table S1. Sampling information and analysis results of all sampling sites in the Yangtze Estuary. Table S2. Detailed information of non-plastic particles found on the filter. Table S3. Comparison of different sized MPs. Table S4. Component matrix of surface water data. Table S5. Component matrix of sediment data. Table S6. Density information of identified polymers in this study. Figure S1. Map of sampling sites. Figure S2. Flow diagram of sample’s transportation. Figure S3. Component plot of surface water data. Figure S4. Component plot of sediment data
Additional file 2 of Association between non-high-density lipoprotein cholesterol and haemorrhagic transformation in patients with acute ischaemic stroke
Creators: name: Wang, Yanan
name: Song, Quhong
name: Cheng, Yajun
name: Wei, Chenchen
name: Ye, Chen
name: Liu, Junfeng
name: Wu, Bo
name: Liu, Ming
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Additional file 2: Table S2. Association of quartiles of Non-HDL-C, LDL-C and symptomatic haemorrhagic transformation.
Annual Review of Advances in Non-small Cell Lung Cancer Research: A Report for the Year 2010
Creators: name: Stinchcombe, Thomas E.
name: Veeramachaneni, Nirmal K.
name: Bogart, Jeffery
name: Kratzke, Robert
name: Govindan, Ramaswamy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: No Abstract.
Electron energy partition across interplanetary shocks: I. Methodology and Data Product
Creators: name: Wilson, Lynn B.
name: Chen, Li-Jen
name: Wang, Shan
name: Schwartz, Steven J.
name: Turner, Drew L.
name: Stevens, Michael L.
name: Kasper, Justin C.
name: Osmane, Adnane
name: Caprioli, Damiano
name: Bale, Stuart D.
name: Pulupa, Marc P.
name: Salem, Chadi S.
name: Goodrich, Katherine A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Space Physics (physics.space-ph)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Analysis of 15314 electron velocity distribution functions (VDFs) within $\pm$2 hours of 52 interplanetary (IP) shocks observed by the \emph{Wind} spacecraft near 1 AU are introduced. The electron VDFs are fit to the sum of three model functions for the cold dense core, hot tenuous halo, and field-aligned beam/strahl component. The best results were found by modeling the core as either a bi-kappa or a symmetric (or asymmetric) bi-self-similar velocity distribution function, while both the halo and beam/strahl components were best fit to bi-kappa velocity distribution function. This is the first statistical study to show that the core electron distribution is better fit to a self-similar velocity distribution function than a bi-Maxwellian under all conditions. The self-similar distribution deviation from a Maxwellian is a measure of inelasticity in particle scattering from waves and/or turbulence. The range of values defined by the lower and upper quartiles for the kappa exponents are $κ{\scriptstyle_{ec}}$ $\sim$ 5.40--10.2 for the core, $κ{\scriptstyle_{eh}}$ $\sim$ 3.58--5.34 for the halo, and $κ{\scriptstyle_{eb}}$ $\sim$ 3.40--5.16 for the beam/strahl. The lower-to-upper quartile range of symmetric bi-self-similar core exponents are $s{\scriptstyle_{ec}}$ $\sim$ 2.00--2.04, and asymmetric bi-self-similar core exponents are $p{\scriptstyle_{ec}}$ $\sim$ 2.20--4.00 for the parallel exponent, and $q{\scriptstyle_{ec}}$ $\sim$ 2.00--2.46 for the perpendicular exponent. The nuanced details of the fit procedure and description of resulting data product are also presented. The statistics and detailed analysis of the results are presented in Paper II and Paper III of this three-part study.
description: 35 pages, 10 figures, 3 tables, under review in Astrophys. J. Suppl [updated in response to 2nd round of referee comments]