cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
X-ray Detection of the Inner Jet in the Radio Galaxy 3C 129
Creators: name: Harris, D. E.
name: Krawczynski, H.
name: Taylor, G. B.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: During the course of an investigation on the interaction of the radio galaxy 3C129 and its ambient cluster gas, we found excess X-ray emission aligned with the northern radio jet. The emission extends from the weak X-ray core of the host galaxy approximately 2.5" to the first resolved radio knot. On a smaller scale, we have also detected a weak radio extension in the same position angle with the VLBA. Although all the evidence suggests that Doppler favoritism augments the emission of the northern jet, it is unlikely that the excess X-ray emission is produced by inverse Compton emission. We find many similarities between the 3C129 X-ray jet and recent jet detections from Chandra data of low luminosity radio galaxies. For most of these current detections synchrotron emission is the favored explanation for the observed X-rays.
description: 7 pages which include 3 b/w figures. Tentatively scheduled for the v578 n1 pt1 ApJ October 10, 2002 issue
The Development of Divinyl-Heteroaryl Linkers for the Synthesis of Stable and Functional Antibody-Drug Conjugates
Creators: name: Walsh, Stephen
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Chemistry
antibody-drug conjugates
bioconjugation

description: Antibody-drug conjugates (ADCs) are a class of targeted therapeutics that utilise the exquisite selectivity of antibodies for membrane receptors to selectively deliver cytotoxic warheads to specific cell types, such as cancer cells. Much effort has been invested in recent years to deliver ADCs with improved pharmacokinetics, toxicology and overall pharmacological profiles over early generation ADCs. In particular, advances in linkage strategies through antibody engineering or enzymatic modification have yielded homogeneous ADC products with defined modification sites and stable linkages. Despite significant advances in this regard, these strategies are typically laborious and low-yielding, and the immunogenicity of these unnatural modifications is still unclear. The primary aim of this work was to obtain a linker technology that yields homogeneous, stable and functional ADCs from native antibodies. To this end, cysteine bridging strategies, whereby a bis-reactive scaffold covalently cross-links the two cysteines of a reduced disulfide, were identified as a reported method to produce homogeneous and functional ADCs. However, a limited number of these reagents have been described in the literature and it was postulated that an expansion of the toolbox of these reagents would be beneficial to the ADC research community. This report details the development of a novel set of divinylpyrimidine (DVP) cysteine bridging linkers. Early investigations into divinylpyridine reagents were initially conducted, but disappointingly, were deemed to have insufficient reactivity to enable efficient antibody disulfide rebridging. Alteration of the divinyl-heteroaryl scaffold by switching to a pyrimidine core was then explored. In the first instance, monovinylpyrimidine small molecule models demonstrated the improved reactivity of the scaffold, while maintaining the stability and chemoselectivity that was observed with the vinylpyridine reagents. DVP linkers including a dual-functional DVP were then readily prepared and were shown to efficiently rebridge the reduced disulfides of native antibodies, antibody fragments and other disulfide-containing proteins. Functionalisation of the protein substrates with biologically-relevant moieties (e.g. cytotoxins, fluorophores) could be achieved either before rebridging with a pre-functionalised linker or after rebridging through bioorthogonal chemistry. In addition, the receptor affinity and cellular selectivity of the antibodies were unaffected by rebridging and the antibody conjugates displayed exceptional stability in human plasma over two weeks. Critically, ADCs synthesised through DVP conjugation demonstrated highly potent and selective cytotoxicity in a series of in vitro cellular assays.
Additional file 2 of Evolutionary analysis and functional characterization of SiBRI1 as a Brassinosteroid receptor gene in foxtail millet
Creators: name: Zhao, Zhiying
name: Tang, Sha
name: Zhang, Yiming
name: Yue, Jingjing
name: Xu, Jiaqi
name: Tang, Wenqiang
name: Sun, Yanxiang
name: Wang, Ruiju
name: Diao, Xianmin
name: Zhang, Baowen
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 2.
Latest measurements of beauty quark production at HERA
Creators: name: Chiochia, V.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The latest results of beauty quark production measurements at HERA are presented. New measurements have been obtained both in the photoproduction and the deep inelastic scattering regimes. The results were compared with the NLO QCD calculations.
description: 3 pages, 2 figures. Talk presented at the 31st International Conference on High Energy Physics (ICHEP02), Amsterdam, The Netherlands, July 24-31, 2002
Adsorption & Adhesion of Asphaltenes at Complex Interfaces: An AFM Approach
Creators: name: Kaimaki, Domna-Maria
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: AFM
Surface science
Complex Interfaces
Contact Mechanics
Adhesion
Adsorption
Asphaltenes
Fouling
Oil-exposed Surfaces
Mitigation strategies

description: Asphaltenes are the heaviest fraction of crude oil, pinpointed as the culprit for the fouling of components throughout the hydrocarbon value chain. The ill-defined nature of asphaltenes has challenged scientists and industry alike, to determine their molecular composition and mitigate their effects respectively. In this thesis, a link between the two approaches is drawn. A model interfacial system was designed and optimised to study the onset of fouling due to the adsorption and adhesion of asphaltenes on relevant surfaces. The effect of surface chemistry on adsorption was originally investigated by examining deposition in the designed system, consisting of synthesised asphaltene molecules and well-defined, atomically flat surfaces. The model molecules examined displayed different deposition behaviour depending on their functionality. AFM morphological characterisation revealed that adsorption occurs at a range of lengthscales, from monomers to flocs, and challenged the concept of a discrete solubility limit. Further optimisation of the system and a multitechnique characterisation approach led to the conclusion that the archipelago asphaltene molecule exhibits the least affinity for oxidised metal surfaces, a model for pipelines. The deposition found on those surfaces is a result of the aggregation of the asphaltene molecules that decreases their individual diffusivity leading to weak physisorption as confirmed by adhesion measurements. An effective mitigation strategy to counteract such adhesion would be the injection of an anti-agglomerant. However, such a strategy needs to be combined with an effort to mitigate the effect of surface roughness on adsorption. Morphological and nanomechanical characterisation of real-life fouled samples revealed the efficacy of an adhesion inhibitor in decreasing roughness and tuning surface chemistry by competitively adsorbing onto the relevant surfaces. A combination of the two mitigating strategies suggested has shown to have an increased potential as an anti-fouling measure. The efficacy of the designed system in identifying such strategies as well as in providing a screening approach for the testing of inhibitors underlines the importance of this work.
description: I held a studentship from the BP International Centre for Advanced Materials (ICAM)
Nature of symmetry breaking at the excitonic insulator transition: Ta$_2$NiSe$_5$
Creators: name: Mazza, Giacomo
name: Rösner, Malte
name: Windgätter, Lukas
name: Latini, Simone
name: Hübener, Hannes
name: Millis, Andrew J.
name: Rubio, Angel
name: Georges, Antoine
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Ta$_2$NiSe$_5$ is one of the most promising materials for hosting an excitonic insulator ground state. While a number of experimental observations have been interpreted in this way, the precise nature of the symmetry breaking occurring in Ta$_2$NiSe$_5$, the electronic order parameter, and a realistic microscopic description of the transition mechanism are, however, missing. By a symmetry analysis based on first-principles calculations, we uncover the \emph{discrete} lattice symmetries which are broken at the transition. We identify a purely electronic order parameter of excitonic nature that breaks these discrete crystal symmetries and contributes to the experimentally observed lattice distortion from an orthorombic to a monoclinic phase. Our results provide a theoretical framework to understand and analyze the excitonic transition in Ta$_2$NiSe$_5$ and settle the fundamental questions about symmetry breaking governing the spontaneous formation of excitonic insulating phases in solid-state materials.
Naturlig teknik - metode bilag
Creators: name: Nielsen, Jonas Vestergaard
Publisher: name: figshare
Year: 2019
Subjects: subject: 80502 Mobile Technologies
subject: FOS: Computer and information sciences

description: Hovedmålet med interviewene er at skabe en forståelse af hvordan målgruppen anvender og tænker om deres brug af smartphones i naturen.
Som supplement til interviewene, blev et landsdækkende spørgeskema konstrueret. Spørgeskemaet tog udgangspunkt i fremtrædende tematikker i interviewene med henblik på at afdække 5.-8. klasseelevers generelle og udendørsbrug af smartphones i fritiden.
Development and implementation of a microresonator impactor for atmospheric particulate sensing
Creators: name: Zielinski, Arthur Timothy
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: Particulate Matter
Aerosol
Microresonator
MEMS
Resonator
Atmospheric Chemistry
Aerosol Science
Engineering
Impactor

description: Recent instrument development for aerosol measurement has focussed on small-scale, on-line measurements that can be incorporated into miniaturised sensor nodes as part of ambient or personal air quality monitoring networks. As a result, optical particle counters (OPCs) have risen in popularity given their ability to consistently size and count individual particles. OPCs have limitations, however, in their inability to detect ultrafine particles (considered the most influential to human health) or to measure particle mass directly (the standard metric for air quality). The growing field of microelectromechanical systems (MEMS) offers a potential alternative by implementing microresonators as mass sensors. MEMS resonators have high mass sensitivities and have recently seen implementation as particulate matter (PM) monitors. The field of MEMS PM instruments is still limited with a variety of implemented resonator topologies and sampling mechanisms. In general, however, they offer real-time, high sensitivity measurements at low flow rates. The aim of this thesis was to further examine the viability of implementing MEMS resonators for PM measurement with a focus on practical considerations for real-world applications. To this end, a new microresonator-based impactor was developed - the MEMS Impactor Stage (MIS) - capable of accommodating various nozzle and resonator combinations. Square lateral bulk acoustic resonators were the primary topology, but the results within the thesis are widely applicable. A series of laboratory studies covered the resonator lifetime, reusability, detection limits, and response to environmental changes. The resonator displayed a high sensitivity throughout, capable of detecting ultrafine particles, but is vulnerable to misinterpretation. Beyond mass measurement, studies introduced possible extensions to hygroscopicity and compositional applications. Ambient particle measurements with the MIS, simulating a real-world application to air quality monitoring, showed the capabilities as a PM instrument while highlighting concerns to be addressed for future instrument design. A microresonator-based impactor has potential as an alternative to OPCs, but its cross sensitivity to deposition patterns and environmental effects must be accounted for prior to implementation as PM monitor.
Supplementary Material from Phylogenetic history of vascular plant metabolism revealed using a macroevolutionary common garden
Creators: name: Neto-Bradley, Barbara M.
name: Muir, Christopher D.
name: Whitton, Jeannette
name: Pennell, Matthew W.
Publisher: name: The Royal Society
Year: 2021
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Plant Biology

description: This supplementary file contains 2 tables and 4 figures. The tables contain a summary of the phylogenetic linear models of Jmax (Table S1) and Vcmax (Table S2). The figures depict a phylogeny of Vcmax (Figure S1) and Jmax (Figure S2), as well as a trait divergence through time plot (Figure S3) and a sensitivity plot of the estimates of Vcmax (Figure S4).
A new evaluation of the hadronic vacuum polarisation contributions to the muon anomalous magnetic moment and to $\mathbf{\boldsymbolα(m_Z^2)}$
Creators: name: Davier, M.
name: Hoecker, A.
name: Malaescu, B.
name: Zhang, Z.
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We reevaluate the hadronic vacuum polarisation contributions to the muon magnetic anomaly and to the running of the electromagnetic coupling constant at the $Z$-boson mass. We include newest $e^+e^- \to$ hadrons cross-section data together with a phenomenological fit of the threshold region in the evaluation of the dispersion integrals. The precision in the individual datasets cannot be fully exploited due to discrepancies that lead to additional systematic uncertainty in particular between BABAR and KLOE data in the dominant $π^+π^-$ channel. For the muon $(g-2)/2$, we find for the lowest-order hadronic contribution $(694.0 \pm 4.0)\cdot10^{-10}$. The full Standard Model prediction differs by $3.3σ$ from the experimental value. The five-quark hadronic contribution to $α(m_Z^2)$ is evaluated to be $(276.0\pm1.0)\cdot10^{-4}$.
description: 13 pages, 9 figures and 2 tables, published version in EPJ-C. arXiv admin note: substantial text overlap with arXiv:1706.09436
Quantum State Discrimination Using Noisy Quantum Neural Networks
Creators: name: Patterson, Andrew
name: Chen, Hongxiang
name: Wossnig, Leonard
name: Severini, Simone
name: Browne, Dan
name: Rungger, Ivan
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Near-term quantum computers are noisy, and therefore must run algorithms with a low circuit depth and qubit count. Here we investigate how noise affects a quantum neural network (QNN) for state discrimination, applicable on near-term quantum devices as it fulfils the above criteria. We find that when simulating gradient calculation on a noisy device, a large number of parameters is disadvantageous. By introducing a new smaller circuit ansatz we overcome this limitation, and find that the QNN performs well at noise levels of current quantum hardware. We also show that networks trained at higher noise levels can still converge to useful parameters. Our findings show that noisy quantum computers can be used in applications for state discrimination and for classifiers of the output of quantum generative adversarial networks.
description: 8 pages, 9 figures
Analysis on Relation Measuring and Development Innovation Path of Tourism Economy in Shenyang Economic Zone
Creators: name: ZHAO, Liang
name: SONG, Xiangye
name: ZHAO, Liang
name: SONG, Xiangye
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Tourism economy relation degree
subject: Shenyang Economic Zone
subject: Development path

description: This article firstly measures the tourism economy relations in Shenyang Economic Zone, and summarizes the spatial structure of tourism economy in Shenyang Economic Zone. The results show that Shenyang is in the central position and its tourism resource has obvious advantages. Finally, this paper provides the development innovation path of tourism economy in Shenyang Economic Zone.
The role of ischaemia-reperfusion injury and mitochondrial dysfunction in organ transplantation
Creators: name: Martin, Jack
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Organ transplantation
Mitochondria
Ischaemia-Reperfusion

description: Summary The role of ischaemia-reperfusion injury and mitochondrial dysfunction in organ transplantation Ischaemia and subsequent reperfusion is inherent to solid organ transplantation and contributes to tissue damage, organ dysfunction, and worse recipient outcome. Demand for organs for transplantation in the UK has led to the increasing use of ‘less-than-ideal’ deceased organs that are less tolerant of ischaemia or have been exposed to greater ischaemic insults. Furthermore, outcomes from clinical transplantation suggest that increasing ischaemia-reperfusion (IR) injury influences not only short-term outcomes but also longer-term outcomes by increasing the rate of chronic organ rejection. Mitochondria are recognised as being integral to IR injury generating a burst of reactive oxygen species that initiates downstream tissue damage. There is emerging evidence that this process is driven by a specific metabolic pathway rather than by a series of random damaging events. A better understanding of this pathophysiology and the mechanisms underpinning IR injury will increase the opportunity for the development of rational therapeutic approaches. In this work, I have characterised ischaemic metabolism during warm and cold organ storage in murine, porcine and human myocardial tissue. I have demonstrated succinate accumulation to be a conserved signature of ischaemia across species and have demonstrated the ability to moderate metabolic pathways in the mouse heart during organ storage using metabolic inhibitors. In order to investigate the effects of the metabolic changes during ischaemia on reperfusion I developed a novel, small animal model of solid organ transplantation incorporating a warm ischaemic insult. I then used this model to examine the therapeutic efficacy of ameliorating succinate accumulation during ischaemia to reduce organ dysfunction upon reperfusion. Finally, I explored the impact of reperfusion injury on chronic rejection in a previously well characterised model of organ rejection. Jack Lewis Martin
description: This work was supported by the Medical Research Council through a Clinical Research Training Fellowship
State Enterprise Zones in Nonmentro Areas: Are They Working?
Creators: name: Robinson, Kenneth L.
name: Reeder, Richard J.
name: Robinson, Kenneth L.
name: Reeder, Richard J.
Publisher: name: Unknown
Year: 1991
Subjects: Community/Rural/Urban Development
Labor and Human Capital

description: State enterprise zone programs appear to be successful economic development tools in nonmetro areas. The programs have created jobs for disadvantaged residents, but most of the jobs are in low-paying, traditional manufacturing industries. Furthermore, many rural areas are excluded from zone participation, either directly, through population and area limitations, or indirectly, through competitive application processes. The effectiveness of zone programs might be improved by changes that would increase rural participation and provide a better mix of jobs.
Wakarumbia hirsuta Dvorak & Bocak 2009, sp. nov.
Creators: name: Dvorak, M.
name: Bocak, L.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Lycidae
Wakarumbia
Wakarumbia hirsuta

description: Wakarumbia hirsuta sp. nov.
(Figs 7–8)
 Type material. Holotype. W. Sulawesi, 25 km E of Mamasa (Kalama), 1100 m, 119.28.39E 3.02.10S, 1.–3. July 2001, Bolm lgt. (LMBC).
 Differential diagnosis. W. hirsuta sp. nov. resembles W. equalis Bocak, 2001 in the relative size of eyes and body coloration. These species can easily be distinguished by the differently rotated apical part of the phallus (Figs 7–8). Additionally, the pronotum of W. hirsuta is much shorter than the pronotum of W. equalis (the width: length ratio is 1.52 and 1.23 in the respective species).
 Description. Body small-sized, slender, uniformly dark brown to black, without any bright patch in elytra, only mouthparts slightly lighter brown. Head small, partly hidden by pronotum, eyes hemispherically prominent, quite small, interocular distance 1.06 times maximum eye diameter. Antennae compressed, antennomeres 3–11 parallel-sided to slightly serrate, antennomere 3 2.4 times longer than maximum width, apical antennomeres apparently slenderer. Pronotum flat, 1.52 times wider than long. Elytra parallel-sided, 3.36 times longer than width at humeri. Phallus slender, slightly rotated in apical half, with short basal tubular part (Figs 7–8).
 Measurements. BL 5.60 mm, HW 1.4 mm, PL 0.66 mm, PW 1.00 mm, EL 4.7 mm, Ediam 0.35 mm, Edist 0.37 mm.
 Distribution. Sulawesi, the Mamasa valley.
 Etymology. The specific epithet refers to the dense recumbent vestiture on elytra.
description: Published as part of Dvorak, M. & Bocak, L., 2009, Ten new species of Wakarumbia Bocak, 1999 from Sulawesi (Coleoptera: Lycidae), with a key to males of the genus, pp. 51-61 in Zootaxa 2282 (1) on page 55, DOI: 10.11646/zootaxa.2282.1.2, http://zenodo.org/record/5305595
Magic wavelength of the $^{138}$Ba$^+$ $6s\;{}^2S_{1/2}-5d\;{}^2D_{5/2}$ clock transition
Creators: name: Chanu, S. R.
name: Koh, V. P. W.
name: Arnold, K. J.
name: Kaewuam, R.
name: Tan, T. R.
name: Zhang, Zhiqiang
name: Safronova, M. S.
name: Barrett, M. D.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The zero crossing of the dynamic differential scalar polarizability of the $S_{1/2}-D_{5/2}$ clock transition in $^{138}$Ba$^+$ has been determined to be $459.1614(28)\,$THz. Together with previously determined matrix elements and branching ratios, this tightly constrains the dynamic differential scalar polarizability of the clock transition over a large wavelength range ($\gtrsim 700\,$nm). In particular it allows an estimate of the blackbody radiation shift of the clock transition at room temperature.
description: 4 pages, 2 figures. Updated based on new branching ratio measurements
Dispersion of imbibition fronts
Creators: name: Melean, Y.
name: Broseta, D.
name: Hasmy, A.
name: Blossey, R.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We have studied the dispersive behaviour of imbibition fronts in a porous medium by X-ray tomography. Injection velocities were varied and the porous medium was initially prewetted or not. At low velocity in the prewetted medium, the imbibition profiles are found to be distinctly hyperdispersive. The profiles are anomalously extended when compared to tracer fronts exhibiting conventional (Gaussian) dispersion. We observe a strong velocity dependence of the exponent characterizing the divergence of the dispersion coefficient for low wetting-fluid saturation. Hyperdispersion is absent at high imbibition velocities or when the medium is not prewetted.
description: 8 pages, 5 figures; submitted to Europhysics Letters
Analysis on Technology Roadmap of Agricultural Equipment Industry in Chongqing
Creators: name: TAN, Chongjing
name: YE, Jin
name: YANG, Shi
name: TAN, Chongjing
name: YE, Jin
name: YANG, Shi
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Agricultural equipment
subject: Industry
subject: Technology roadmap

description: Since the subsidizing agricultural machine purchase was launched in 2004, the agriculture equipment industry in Chongqing has progressed by leaps and bounds, but it is still faced with a few urgent problems, which requires the coordination of stakeholders, with an aim to establish a clear direction of the development of industry and a technology route. With planting industry as an example, this paper applies the principle and method of industry technology roadmap to analyse the market demand, industry target, technology barrier and R & D demand of agricultural equipment industry in Chongqing. Based on the results, the top technology R & D items of agricultural equipment industry in Chongqing are obtained. Finally, the following suggestions are put forward: integrating resources, constructing platform and improving innovation ability; constructing agricultural industry park and promoting clustered development of agricultural equipment industry; strengthening finance and taxation support; strengthening construction of agricultural mechanization infrastructure; substantially developing socialized service of agricultural machinery.
Geometric Induction in Chiral Superconductors
Creators: name: Jiang, Qing-Dong
name: Hansson, T. H.
name: Wilczek, Frank
Publisher: name: arXiv
Year: 2019
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We consider a number of effects due to the interplay of superconductivity, electromagnetism and elasticity, which are unique for thin membranes of layered chiral superconductors. Some of them should be within the reach of present technology, and could be useful for characterizing materials. More speculatively, the enriched control of Josephson junctions they afford might find useful applications.
description: published version
A Unified Description of the Timing Features of Accreting X-ray Binaries
Creators: name: Belloni, Tomaso
name: Psaltis, Dimitrios
name: van der Klis, Michiel
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We study an empirical model for a unified description of the power spectra of accreting neutron stars and black holes. This description is based on a superposition of multiple Lorentzians and offers the advantage that all QPO and noise components are dealt with in the same way, without the need of deciding in advance the nature of each component. This approach also allows us to compare frequencies of features with high and low coherences in a consistent manner and greatly facilitates comparison of power spectra across a wide range of source types and states. We apply the model to six sources, the low-luminosity X-ray bursters 1E 1724-3045, SLX 1735-269 and GS 1826-24, the high-latitude transient XTE J1118+480, the bright system Cir X-1, and the Z source GX 17+2. We find that it provides a good description of the observed spectra, without the need for a scale-free (1/f) component. We update previously reported correlations between characteristic frequencies of timing features in the light of this new approach and discuss similarities between different types of systems which may point towards similar underlying physics.
description: 13 pages, to appear in The Astrophysical Journal
An investigation of the interaction between the immune system GTPase GIMAP6 and an autophagy gene 8 homologue GABARAPL2
Creators: name: Mukadam, Aamir
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: GTPases
GIMAPs
autophagy

description: The GTPase of immunity-associated proteins (GIMAP) is expressed in eukaryotic phyla including a subset of molluscs, vertebrates, and some protists. It is predominantly ex- pressed in the lymphoid organs of mammals and other vertebrates where it plays roles in the homeostasis of the immune system. My study focuses on human (h) GIMAP6, a cytosolic member of the GIMAP family that is widely expressed across the lymphoid lineages. Studies within our group have uncovered a highly specific interaction between GIMAP6 and hGABARAPL2 (gamma- aminobutyric acid receptor-associated protein-like 2), a mammalian homologue of the autophagy-related protein 8 (Atg8). Using bacterially expressed GABARAPL2 and GIMA- P6 I have shown that the interaction between the two proteins is direct. My studies have attempted to gain an understanding of the molecular requirements for this interaction using site-directed mutagenesis and pull-down assays. Mutational analyses, including point mutations within, and truncations of, GIMAP6 and GABARAPL2 have revealed a number of things. Close to its N-terminus GIMAP6 carries a sequence correspond- ing to a canonical Atg8 interacting motif (AIM), a motif frequently found in proteins that interact with the Atg8 family. My studies indicate, however, that these residues do not play a role in the interaction. Using GTP-agarose, I was able to demonstrate that GIMAP6 could bind GDP and GTP and by mutating key residues within its GTP bind- ing domain, I could disrupt the interaction of GIMAP6 with GABARAPL2. I have also shown that the C-terminal 10 amino acids of GIMAP6 are necessary for the interaction. Interestingly, variants of GIMAP6 that were unable to bind GTP-agarose were also un- able to interact with GABARAPL2, hinting at a crucial role for nucleotide binding in the GIMAP6-GABARAPL2 interaction. Within GABARAPL2, deletion of the N-terminal α-helix resulted in loss of the interaction. A chimeric protein in which the correspond- ing region in MAP1LC3B, a protein unable to interact with GIMAP6, was replaced by GABARAPL2’s N-terminal α-helix reproduced the interaction suggesting that this region is critical for the interaction. Studies in our group have shown that GIMAP6 relocalises to autophagosomes on induction of autophagy. I have shown that variants of GIMAP6 unable to interact with GABARAPL2 fail to display a similar relocalisation. Finally, recent research has demonstrated that members of the GIMAP family can homo- and hetero-dimerise. I have shown that GIMAP6 can interact with itself and intriguingly, also shows a specific interaction with GIMAP7. Contrary to what was observed for the GIMAP6-GABARAPL2 interaction, truncating the N-terminus of GIMAP6 abrogated the interaction with GIMAP7. These findings evoke the possibility that the GIMAP GTPases function together in an interacting network.
Rural Banks in Good Shape, S&L's a Potential Trouble Spot
Creators: name: Rossi, Clifford
name: Rossi, Clifford
Publisher: name: Unknown
Year: 1991
Subjects: Agricultural Finance
Financial Economics

description: News these days about the shape of the Nation's financial institutions is not so good. The insurance fund backing bank deposits recently required replenishment, the cost of the thrift savings and loan (S&L) crisis is still unknown, and even the largest banks in the country have seen their balance sheets deteriorate markedly during recent years. While ailing financial institutions are not confined to big cities, rural financial institutions are generally in better shape than urban ones.
Chirally improved Dirac operators: Studying the sensitivity to topological excitations for zero and finite temperature
Creators: name: Gattringer, Christof
name: Göckeler, Meinulf
name: Lang, C. B.
name: Rakow, P. E. L.
name: Schaefer, Stefan
name: Schäfer, Andreas
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We discuss the construction and properties of an approximate solution of the Ginsparg-Wilson equation, the so-called chirally improved lattice Dirac operator. In particular we study the behavior of its eigenmodes in smooth instanton backgrounds as well as for thermalized gauge configurations on both sides of the QCD phase transition. We compare with results from other Dirac operators including the overlap operator. The results support the picture of chiral symmetry breaking being closely related to instantons.
description: Lattice2001(confinement), 9 pages, 8 figures
Poincaré Maps for Multiscale Physics Discovery and Nonlinear Floquet Theory
Creators: name: Bramburger, Jason J.
name: Kutz, J. Nathan
Publisher: name: arXiv
Year: 2019
Subjects: subject: Dynamical Systems (math.DS)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: Poincaré maps are an integral aspect to our understanding and analysis of nonlinear dynamical systems. Despite this fact, the construction of these maps remains elusive and is primarily left to simple motivating examples. In this manuscript we propose a method of data-driven discovery of Poincaré maps based upon sparse regression techniques, specifically the sparse identification of nonlinear dynamics (SINDy) algorithm. This work can be used to determine the dynamics on and near invariant manifolds of a given dynamical system, as well as provide long-time forecasting of the coarse-grained dynamics of multiscale systems. Moreover, the method provides a mathematical formalism for determining nonlinear Floquet theory for the stability of nonlinear periodic orbits. The methods are applied to a range of examples including both ordinary and partial differential equations that exhibit periodic, quasi-periodic, and chaotic behavior.
A Relativistic Fe K-alpha Emission Line in the Intermediate Luminosity BeppoSAX Spectrum of the Galactic Microquasar V4641 Sgr
Creators: name: Miller, J. M.
name: Fabian, A. C.
name: Zand, J. J. M. in 't
name: Reynolds, C. S.
name: Wijnands, R.
name: Nowak, M. A.
name: Lewin, W. H. G.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Broad Fe K-alpha emission lines have recently been reported in a number of Galactic black holes. Such lines are useful accretion flow diagnostics because they may be produced at the inner accretion disk and shaped by relativistic effects, but in general they have only been observed at luminosities of L_X ~ 10^(37-38) erg/s in soft X-rays. The Galactic microquasar V4641 Sgr -- widely known for its 12.2 Crab (1.5-12 keV) outburst in 1999 September -- displayed low-level activity in 1999 March. BeppoSAX observed the source in this state and Fe K-alpha line emission was found (in 't Zand et al. 2000). In re-analyzing these data, we find strong evidence that the Fe K-alpha line profile is broadened. For the most likely values of the source distance and black hole mass measured by Orosz et al. (2001), our fits to the total spectrum indicate that the source was observed at a luminosity of L_X = 1.9 (+1.0, -0.8) * 10^(36) erg/s (2-10 keV), or L_X/L_Edd. = 1.8 (+0.9, -0.8) * 10^(-3). Advection-dominated accretion flow (ADAF) models predict a radially-recessed disk in this regime. In contrast, fits to the observed Fe K-alpha emission line profile with a relativistic line model constrain the inner disk to be consistent with the marginally stable circular orbit of a Schwarzschild black hole.
description: 5 pages, 3 color figures. ApJ Letters, in press
The Development Model of Agricultural Insurance in Anhui Province
Creators: name: YOU, Pu
name: YOU, Pu
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Agricultural insurance
subject: Development model
subject: Government leading

description: The agricultural economy in Anhui Province is developing so fast, but farmers are severely affected by the frequent occurrence of natural disasters. The current agricultural insurance mode is not suitable, therefore, the research on agricultural insurance modes of Anhui Province helps to promote the steady development of the agricultural production. Starting from situation of agricultural insurance in Anhui Province, learning from both experience of foreign country and the latest successful domestic modes, we try to put forward agricultural insurance mode framework which is suitable for Anhui Province. Based on the actual situation of Anhui Province, it is necessary to adopt the mode of government leading combined with agricultural mutual aid rather than copy the existing mode.
Constraints on the cosmic string loop collapse fraction from Primordial Black Holes
Creators: name: James-Turner, Chloe
name: Weil, Danton P. B.
name: Green, Anne M.
name: Copeland, Edmund J.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A small fraction, $f$, of cosmic string loops can collapse to form Primordial Black Holes (PBHs). Constraints on the abundance of PBHs can therefore be used to constrain $f$. We update these calculations, taking into account the PBH extended mass function, and find $f < 10^{-31} (G μ/ c^2)^{-3/2}$. This is roughly two orders of magnitude tighter than previous constraints. The improvement from the tighter constraints on the abundance of PBHs is partly off-set by refinements to the theoretical calculation of the cosmic string loop formation rate.
description: 5 pages, v2: takes into account only a fraction of string network energy goes into long loops, constraints consequently weakened by one order of magnitude (thank you to referee for pointing this out) + other minor changes
Phase-Change Materials and Biochar: Some New Composite Materials in Recent Literature
Creators: name: Sparavigna, Amelia Carolina
Publisher: name: Zenodo
Year: 2021
Subjects: PCM
PCC
Biochar
Composite Materials
Biomass-Based Porous Carbon
Phase Change Composites
Thermal Management
Latent Heat Storage Biocomposite
LHSBC
Materials Science

description: A phase change material (PCM) is a substance absorbing and releasing energy at phase transition. The substance is therefore useful for heating and cooling applications. Here we review the recent literature about the use of biochar and PCMs for composite materials, to obtain phase change composites (PCCs).
A comparative study of Urraca of León-Castilla (d. 1126), Melisende of Jerusalem (d. 1161), and Empress Matilda of England (d. 1167) as royal heiresses
Creators: name: Koch, Jessica
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Medieval History
Urraca of León-Castilla
Melisende of Jerusalem
Empress Matilda
queen regnant
royal heiress
aristocratic heiress
12th century

description: This dissertation is a comparative study of Urraca of León-Castilla (r. 1109–1126), Melisende of Jerusalem (r. 1131–1153–d. 1161), and the Empress Matilda of England and Normandy (b. 1102–d. 1167). Despite the vast research on aristocratic heiresses and queens consorts, a comparative study of royal heiresses as rulers in their own right does not exist. The few studies that focus on royal heiresses examine individual royal women or are region-specific studies. However, by studying royal heiresses comparatively, greater insight can be gained regarding the challenges women faced in their attempt to gain the throne, the methods they employed to keep power, and the unique variations of rulership that are specific to each queen regnant. In general, medieval society expected royal power would be held by men, but in the absence of a male heir, women, on occasion, held royal office. This study observes how royal heiresses could mostly, but not always, overcome the limitations of their gender to establish a rule in their respective kingdoms. This thesis explores aspects of rulership over five chapters, aimed at understanding how a royal heiress might succeed or fail to gain the throne, keep the throne, and preserve it for future generations. Through the use of a comparative methodology, this thesis provides a fresh discussion of royal heiresses as rulers. It shows that royal heiresses faced different obstacles to their rule than their aristocratic counterparts and, that because of their royal status, they were able to overcome complications that aristocratic heiresses could not. Demonstrations of female power were, in many cases, approved of at the royal level but were condemned at the aristocratic level, as was the case for Melisende of Jerusalem and her younger sister, Alice of Antioch (c. 1110–1136). Studying Urraca of León-Castilla, Melisende of Jerusalem, and the Empress Matilda side-by-side, this thesis also establishes the individual pitfalls of female rulership and identifies the methods each aspiring queen regnant utilized in order to overcome them.
"Study to assess the effectiveness of video assisted teaching cum live demonstration on knowledge and practice regarding prevention of cauti (catheter associated urinary tract infection) among staff nurses working in surgical ward at selected hospital of jabalpur (m.p.)"
Creators: name: Priyanka Patel
name: Dr. Berlin Sara Thampy
Publisher: name: SCIENTIFIC JOURNAL
Year: 2025

description: A urinary tract infection (UTI) is an infection involving any part of the urinary system, including urethra bladder, ureters & kidney. As per National Healthcare Safety Network (NHSN) report UTIs are the most common type of healthcare associated infections. Among UTIS acquired in the hospital, approximately 75% are associated with a urinary catheter, the single most important predisposing factor for CAUTI is the insertion of urinary catheter. Urinary catheters are used frequently in hospitalized patients, and almost 25% of them undergo urinary catheterization during their stay in the hospital.Prevention of catheter associated urinary tract infection(CAUTI) is an important component of the delivery of the safe quality care. UTI is the most common hospital acquired infection, according for 40% of all the nosocomial infections (Saint et all 2008).CAUTI has been a leading cause of increased health costs & patient  discomfort, in addition to the increased morbidity & mortality in hospitalised patients (Saint, et al.2008).There is immense need to develop EBP on these related measures from the day of insertion to removal of catheter. Hence this study is focused on nursing care in surgical wards among indwelling catheterised patients.
Development of a Hybrid Photo-Diode and its Front-End Electronics for the BTEV Experiment
Creators: name: Mountain, R. J.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: This paper describes the development of a 163-channel Hybrid Photo-Diode (HPD) to be used in the RICH Detector for the BTEV Experiment. This is a joint development project with DEP, Netherlands. It also reports on the development of associated front-end readout electronics based on the va_btev ASIC, undertaken with IDEAS, Norway. Results from bench tests of the first prototypes are presented.
description: Presented at Fourth International Workshop on RICH Detectors, Pylos Greece, June, 2002; to appear in the proceedings. (5 pages, 4 figures)
Risk Management Strategies for Drought-Prone Rice Cultivation: A Case Study of Tamil Nadu, India
Creators: name: Selvaraj, K.N.
name: Selvaraj, K.N.
Publisher: name: Unknown
Year: 2009
Subjects: Agricultural and Food Policy
Farm Management
Productivity Analysis

description: This study aimed to understand the issues associated with rainfed rice production in dry and semidry areas in Tamil Nadu, India. Farmers face risks such as input, output, market-price, and income, as these areas are prone to rainfall shortage. Secondary data about Tamil Nadu and various water limited rice environments were studied. A farm survey of 230 farm households in selected districts was conducted in 2001-02 and 2003-04. Fertilizer use in rainfed areas was reduced due to rainfall shortage. In drought period, crop response to fertilizer declined, causing a decrease in rice yields. Yield variability was higher (44 percent to 60 percent) in drought-prone areas. In rainfed areas, a 10-percent increase in drought risk resulted in a 5.4 percent decline in the yield of modern varieties. In contrast, the effect on landraces was minimal. Farmers in the rainfed areas are operating at sub-optimal level of Production. About 90 percent were inefficient since crop yields were lower than the optimal yield. Farmers incurred an additional cost of INR 899 to increase yield by 228 kg/ha. An increase in rice productivity by one ton per hectare would replace rice area by 189,208 hectares in Tamil Nadu. Area expansion under rice was noticed in the selected rainfed areas, revealing that infusing high productivity traits in drought-tolerant rice varieties enable farmers to allocate part of their land to other crops. Traits (genetic and marketability) of widely adopted modern varieties and landraces should be considered in breeding varieties for water-limited environments to earn profits. The results confirm that drought intensity is higher during the maximum-tillering stage, therefore, continued research on development of drought-tolerant rice varieties to withstand early drought is crucial. Finally, rice income variability in rainfed areas was explained more by variability in yields rather than prices both during normal and risk periods. In other areas, income variability was due to price variability. Yield stabilization would be more effective in keeping revenues stable in rainfed areas, while price stabilization, is an appropriate strategy for reducing revenue risk in irrigated areas.