cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Antiretroviral Therapy Initiated During Acute HIV Infection Fails to Prevent Persistent T-Cell Activation
Creators: name: Eron, Joseph J.
name: Cope, Anna
name: Ferrari, Guido
name: Kuruc, Joann D.
name: Hicks, Charles B.
name: Margolis, David M.
name: Gay, Cynthia L.
name: McGee, Kara S.
name: Vinikoor, Michael J.
name: Lennox, Jeffrey L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Initiation of ART during acute HIV-1 infection may prevent persistent immune activation. We analyzed longitudinal CD38+HLA-DR+ CD8+ T cell percentages in 31 acutely infected individuals who started early (median 43 days since infection) and successful ART, and maintained viral suppression through 96 weeks. Pre-therapy a median of 72.6% CD8+ T cells were CD38+HLA-DR+, and while this decreased to 15.6% by 96 weeks, it remained substantially higher than seronegative controls (median 8.9%, p=0.008). Shorter time to suppression predicted lower activation at 96 weeks. These results support the hypothesis that very early events in HIV-1 pathogenesis may result in prolonged immune dysfunction.
CuPt/CNT catalysts for oxygen reduction prepared by a facile two-step synthesis : chemical vs. electrochemical leaching
Creators: name: El-Deeb, Heba
name: Nassr, Abu Bakr Ahmed Amine
name: Bron, Michael
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 540

description: Cu@Pt/CNT electrocatalysts were prepared by a facile two-step impregnation process. Pt nanoparticles supported on CNTs were prepared by microwave-assisted polyol reduction followed by impregnation with a copper precursor. The final catalysts were obtained by thermal alloying at different temperatures; namely 600, 800, 1000 °C. The alloying extent between Pt and Cu was found to increase significantly with the alloying temperature as revealed from XRD analysis, as does the particle size obtained from TEM. Electrochemical dealloying was performed with the three different Cu@Pt/CNT catalysts, aiming to form a core shell structure. The formation of a Pt enriched surface upon dealloying was confirmed electrochemically by cyclic voltammtery and CO stripping. The electrocatalytic activity for oxygen reduction of the electrochemically dealloyed catalysts depends on the alloying temperature where the catalyst alloyed at 800 °C showed the highest surface specific activity, which is explained in view of the high Cu content in the alloy core compared to the sample alloyed at 600 °C. Alloying at 1000 °C and chemical/electrochemical leaching leads to porous structures with high activity, albeit lower than that of the 800 °C sample. Notably these porous particles provide high activity also with a low copper content in the core. In general, the dealloyed Cu@Pt/CNT catalysts showed higher catalytic activity both in terms of surface specific activity (SSA) and mass specific activity (MSA) than their Pt/CNT counterpart.
Circulating Levels of Tissue Factor Microparticle Procoagulant Activity Are Reduced With Antiretroviral Therapy and Are Associated With Persistent Inflammation and Coagulation Activation Among HIV-Positive Patients
Creators: name: Bradford, Robert L.
name: Huppler Hullsiek, Katherine
name: Baker, Jason V.
name: Prosser, Rachel
name: Tracy, Russell P.
name: Key, Nigel S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Activation of coagulation pathways may contribute to risk for non-AIDS related conditions among HIV positive patients. We measured tissue factor-dependent procoagulant activity on circulating microparticles (MP-TF) in the plasma of 163 HIV positive participants, both untreated and treated, with viral suppression. MP-TF activity was 39% lower among treated versus untreated participants (p<0.001), which persisted in adjusted models (−36%; p=0.03). Among treated participants, MP-TF activity correlated modestly with D-dimer (r=0.24; p=0.01), vWF (r=0.36; p<0.001), and IL-6 (r=0.20; p=0.04) levels. Future research should focus on mechanisms driving residual functional TF activity and whether these alterations have clinical consequences for non-AIDS defining complications.
Additional file 1 of Developmental disparities in sedentary time by period of the day among US youth: a cross-sectional study
Creators: name: Santiago-Rodríguez, María Enid
name: Chen, Jinsong
name: Pfeiffer, Karin A.
name: Marquez, David X.
name: Odoms-Young, Angela
name: Bustamante, Eduardo Esteban
Publisher: name: figshare
Year: 2022
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Table A1. Accelerometer Data Processing Specifications [35, 36].
The Status of the Hungarian Gravimetric Network - Absolute measurements until 2021
Creators: name: Kis, Márta
Publisher: name: Zenodo
Year: 2022
Subjects: Hungarian
Gravimetric
Network
absolute gravimetric measurements
network maintenance

description: The Hungarian Gravimetric Network (MGH) has been existing since the early 1950s, it was created and maintained, developed by the Eötvös Lorand Geophysical Institute of the Hungarian State (MÁELGI) and its successors. Presently, as the actual successor of Mining and Geological Survey of Hungary, MGH is handled by the Supervisory Authority of Regulatory Affairs (SZTFH, Budapest, Hungary). The network went through modernization; following the earlier ‘Vienna’ and ‘Potsdam’ reference systems it has been absolute-based, since the late 1980s. The latest adjustment of the network was performed in 2013, where the mean error was ±0.01386 mGal. The MGH recently contains 25 absolute (0th order) stations, as well as 435 1st and 2nd order base points. In order to improve the reliability and accuracy of the network, the absolute value of gravity acceleration is redetermined in every 7-10 years on ‘normal’ absolute stations, furthermore in every 2-7 years on the national gravimetric main base point (in the Budapest-Mátyáshegy Gravity and Geodynamical Observatory). The absolute (0th order) stations of the network form the ‘national gravity etalon’ in Hungary, where the term is the actualization of absolute g values within 10 years on every station. In Hungary 82 absolute measurements have been carried out since 1978. Hungary doesn’t possess absolute gravimeter, the measurements are ordered (ab. 3 stations in every year). From 2007 until now, the absolute measurements in Hungary are carried out by the VÚGTK (Research Institute of Geodesy, Topography and Cartography, v.v.i.), Czech Republik. Before (or within a short time interval around) the absolute measurements, vertical gravity gradient (VG) values are determined on the stations by LCR-G relative gravity meters, using a 3-level arrangement and at least 6 series of measurements of 2-3 instruments. In 2 observatories operated by the SZTFH, in Budapest and Tihany, changes of gravity field are continuously monitored by relative LCR-G gravity meters. In the 1990s a partial network of MGH consisting of 45 adequately selected 0th, 1st and some 2nd order base points joined the Unified European Gravimetric Network (UEGN). This partial network was then connected to corresponding base points of Austrian and Slovakian networks, based on cooperation with BEV (Federal Office of Metrology and Surveying, Austria) and GKÚ (Geodetic and Cartographic Institute Bratislava, Slovakia). Recent questions, open problems of the network maintenance will be also discussed.
PACBOARD presentation at the R for HTA workshop 2023
Creators: name: Pouwels, Xavier G.L.V.
Publisher: name: Zenodo
Year: 2023
Subjects: Health Economics
Validation
Dashboard
Open source

description: This presentation of the Probabilistic Analysis Check dashBOARD (PACBOARD) was given during the 2023 R for HTA workshop (8 June 2023).
Comparative Effectiveness of Fish Oil Versus Fenofibrate, Gemfibrozil, and Atorvastatin on Lowering Triglyceride Levels Among HIV-Infected Patients in Routine Clinical Care
Creators: name: Muñoz, Monica A.
name: Hunt, Peter W.
name: Mathews, W. Chris
name: Kahn, James O.
name: Eron, Joseph J.
name: Mugavero, Michael J.
name: Liu, Wei
name: Willig, James H.
name: Brown, Elizabeth
name: Crane, Heidi M.
name: Delaney, Joseph A.C.
name: Kitahata, Mari M.
name: Saag, Michael S.
name: Napravnik, Sonia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The goal of this study was to compare the effectiveness of fish oil, fenofibrate, gemfibrozil, and atorvastatin on reducing triglyceride (TG) levels among a large cohort of HIV-infected patients in clinical care.
Mate copying requires the coincidence detector Rutabaga in the mushroom bodies of Drosophila melanogaster
Creators: name: Nöbel, Sabine
name: Danchin, Etienne
name: Isabel, Guillaume
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 590

description: Mate choice constitutes a major fitness-affecting decision often involving social learning leading to copying the preference of other individuals (i.e., mate copying). While mate copying exists in many taxa, its underlying neurobiological mechanisms remain virtually unknown. Here, we show in Drosophila melanogaster that the rutabaga gene is necessary to support mate copying. Rutabaga encodes an adenylyl cyclase (AC-Rut+) acting as a coincidence detector in associative learning. Since the brain localization requirements for AC-Rut+ expression differ in classical and operant learning, we determine the functional localization of AC-Rut+ for mate copying by artificially rescuing the expression of AC-Rut+ in neural subsets of a rutabaga mutant. We found that AC-Rut+ has to be expressed in the mushroom bodies’ Kenyon cells (KCs), specifically in the γ-KCs subset. Thus, this form of discriminative social learning requires the same KCs as non-social Pavlovian learning, suggesting that pathways of social and asocial learning overlap significantly.
Implementation of brachytherapy for patients with cervical cancer in Ethiopia : a 3-year practice report
Creators: name: Kibret, Yitbarek M.
name: Tigeneh, Wondemagegnehu
name: Jemal, Ahmedin
name: Kantelhardt, Eva Johanna
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 618

description: PURPOSE: Although cervical cancer is the second most commonly diagnosed cancer in Ethiopia, brachytherapy (BT) was not a component in patient treatment until 2015. The purpose of this study was to identify the patterns of utilization as well as to describe the practice of BT in Ethiopia. MATERIALS AND METHODS: A retrospective descriptive data analysis of 138 patients with cervical cancer treated with a curative potential using BT from 2015 to 2018 at Tikur Anbassa Specialized Hospital, which housed the only BT facility in Ethiopia during the study period. RESULTS: During the first 3-year period of BT service commencement, each year n = 37, n = 36, and n = 65 patients with cervical cancer were treated, respectively, with curative intention treatment. The median age of these 138 patients was 50 years (range, 22-75). All the patients were in International Federation of Gynecology and Obstetrics stage Ib–IIIb group, and stage IIb (66.4%) was the predominant. Majority (79%) of the patients were treated primarily with radiotherapy (RT), while 21% received RT after surgery. More than half of these patients (62%) received a total RT dose of 82 Gy in equivalent dose in 2 Gy fractions (EQD2), while the rest received a dose ranging from 76 to 86 Gy. Concurrent cisplatin with RT was given only for 36% of the patients for undocumented reasons. The overall treatment time including both external-beam RT and BT was greater than 8 weeks in 21% of the patients. CONCLUSION: The utilization of BT service increased gradually and BT enabled the delivery of a higher RT dose to patients with cervical cancer (mostly stage IIB). However, there was protracted treatment duration and low concurrent chemotherapy utilization.
Additional file 2 of Developmental disparities in sedentary time by period of the day among US youth: a cross-sectional study
Creators: name: Santiago-Rodríguez, María Enid
name: Chen, Jinsong
name: Pfeiffer, Karin A.
name: Marquez, David X.
name: Odoms-Young, Angela
name: Bustamante, Eduardo Esteban
Publisher: name: figshare
Year: 2022
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Table A2. Description of the Linear Regression Syntax for SAS.
Correctional Facilities as Partners in Reducing HIV Disparities
Creators: name: DiClemente, Ralph
name: Rich, Josiah D.
name: Dumont, Dora
name: Ruiz, Monica S.
name: Lyda, Karen
name: Levy, Judith
name: Rosen, David L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The U.S. now has the highest incarceration rate in the world. The majority of prison and jail inmates come from predominantly nonwhite and medically underserved communities. Although incarceration has adverse effects on both individual and community health, prisons and jails have also been used successfully as venues to provide health services to people with HIV who frequently lack stable health care. We review demographic trends shaping the difficulties in providing care to incarcerated people with HIV, and recommend the Centers for AIDS Research Collaboration on HIV in Corrections (CFAR-CHIC) as a model of interdisciplinary collaboration in addressing those difficulties.
Stability of Erdős-Ko-Rado Theorems in Circle Geometries
Creators: name: Adriaensen, Sam
Publisher: name: arXiv
Year: 2022
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05B25, 05C50, 05E30, 51E20

description: Circle geometries are incidence structures that capture the geometry of circles on spheres, cones and hyperboloids in 3-dimensional space. In a previous paper, the author characterised the largest intersecting families in finite ovoidal circle geometries, except for Möbius planes of odd order. In this paper we show that also in these Möbius planes, if the order is greater than 3, the largest intersecting families are the sets of circles through a fixed point. We show the same result in the only known family of finite non-ovoidal circle geometries. Using the same techniques, we show a stability result on large intersecting families in all ovoidal circle geometries. More specifically, we prove that an intersecting family $\mathcal F$ in one of the known finite circle geometries of order $q$, with $|\mathcal F| \geq \frac 1 {\sqrt2} q^2 + 2 \sqrt 2 q + 8$, must consist of circles through a common point, or through a common nucleus in case of a Laguerre plane of even order.
description: 18 pages
libyt: a Tool for Parallel In Situ Analysis with yt
Creators: name: Tsai, Shin-Rong
name: Schive, Hsi-Yu
name: Turk, Matthew J.
Publisher: name: Zenodo
Year: 2022
Subjects: data analysis
in situ analysis

description: In the era of exascale computing, storage and analysis of large-scale data have become increasingly more important and difficult. In situ analysis provides a promising solution to this challenge. Here we present libyt (https://github.com/calab-ntu/libyt), an open source C++ library allowing astrophysical simulations to analyze and visualize data with yt or other Python packages in parallel during simulation runtime. We describe the methods for reading adaptive mesh refinement data structure, accessing and handling in-memory cell-centered, face-centered, and particle data with minimal memory overhead, and exchanging data among parallel processes. We provide concrete examples of incorporating libyt to a simulation code. Furthermore, we demonstrate its capability with two astrophysical simulations, fuzzy dark matter vortices and core-collapse supernovae, with the code GAMER.
Pancosmic Relativity and Nature's Hierarchies
Creators: name: Kaloper, Nemanja
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We define `third derivative' General Relativity, by promoting the integration measure in Einstein-Hilbert action to be an arbitrary $4$-form field strength. We project out its local fluctuations by coupling it to another $4$-form field strength. This ensures that the gravitational sector contains only the usual massless helicity-2 propagating modes. Adding the charges to these $4$-forms allows for discrete variations of the coupling parameters of conventional General Relativity: $G_N, Λ, H_0$, and even $\langle {\tt Higgs }\rangle$ are all variables which can change by jumps. Hence de Sitter is unstable to membrane nucleation. Using this instability we explain how the cosmological constant problem can be solved. The scenario utilizes the idea behind the irrational axion, but instead of an axion it requires one more $4$-form field strength and corresponding charged membranes. When the membrane charges satisfy the constraint $\frac{2κ_{\tt eff}^2 κ^2 |{\cal Q}_i|}{3{\cal T}^2_i} < 1$, the theory which ensues exponentially favors a huge hierarchy $Λ/\mpl^4 \ll 1$ instead of $Λ/\mpl^4 \simeq 1$. The discharges produce the distribution of the values of $Λ$ described by the saddle point approximation of the Euclidean path integral.
description: 53 pages LaTeX, 8 .pdf figures v3: version published in PRD, more comments and references added
A Data Science environment for climate change research at CMCC
Creators: name: Elia, Donatello
name: Nassisi, Paola
name: Palazzo, Cosimo
name: Antonio, Fabrizio
name: Sbarro, Bernardo
name: D'Anca, Alessandro
name: Fiore, Sandro
name: Aloisio, Giovanni
Publisher: name: Zenodo
Year: 2019

description: Poster about "A Data Science environment for climate change research at CMCC" presented at the CMCC Annual Meeting 2019, 4-5 June 2019, Marina di Ugento (Lecce), Italy
Non-Abelian chiral spin liquid on spin-1 kagome lattice: truncation of an exact Hamiltonian and numerical optimization
Creators: name: Jaworowski, Błażej
name: Nielsen, Anne E. B.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We search for short-range Hamiltonians of finite spin-1 kagome systems, maximizing the overlaps with lattice Moore-Read states. Our starting point is an exact, long-range parent Hamiltonian for such a state on a finite plane, obtained from conformal field theory. A truncation procedure is applied to it, which retains only short-range terms and makes it easy to define the Hamiltonian on a torus. Finally, the remaining coefficients are optimized, to yield maximized overlaps between exact diagonalization results and model ground states. In the best cases, these overlaps exceed 0.9 and 0.8 for the three lowest states of 12- and 18-site systems, respectively, suggesting that the obtained Hamiltonians are good parent Hamiltonians for a non-Abelian topological order.
description: This is the final version published in PRB. Some changes (incl. a new section) were made to clarify the presentation and discuss the relation to other works. During the review process, we realized that (6) and (11) are equivalent to the wavefunction and the Hamiltonian (respectively) from [44], which influenced the discussion but not the results. Typos and minor mistakes were corrected
libyt: A Tool for In-Situ Parallel Analysis and its Scientific Applications
Creators: name: Shin-Rong Tsai
Publisher: name: Zenodo
Year: 2022
Subjects: data analysis

description: The size and scale of simulations have grown rapidly in order to solve larger physics problems and to render the data in a higher resolution. This resulted in bigger dataset in each step in simulations. Analytic tools have been developed to analyze and visualize these output datasets, but they suffer from having simulations to store the full datasets on disk first before further analyzing them. This may take up lots of disk space if we want to analyze the data in a high resolution time series. This also wastes lots of space storing unnecessary data, if we only need a small portion from them. We developed libyt to solve this problem. libyt is a C++ library for yt, that aims to make simulations able to use yt or other Python packages to analyze data arbitrarily in code runtime. We describe how libyt is built and demonstrate that it plays an important role in large simulations. We also show the advantage of using libyt and how it can be extended and connected to other analytic tools in the upcoming updates.
Decreasing Excess Mortality of HIV-Infected Patients Initiating Antiretroviral Therapy: Comparison with Mortality in General Population in China, 2003–2009
Creators: name: Zhao, Decai
name: Cole, Stephen R.
name: Zhang, Yao
name: Zhang, Fujie
name: Zhu, Hao
name: Liu, Xia
name: Liu, Zhongfu
name: Dou, Zhihui
name: Cohen, Myron S.
name: Yu, Lan
name: Wohl, David A.
name: Ma, Ye
name: Napravnik, Sonia
name: Eron, Joseph J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: To evaluate excess mortality across calendar time comparing HIV-infected patients receiving cART with the general Chinese population.
Dolutegravir Pharmacokinetics in the Genital Tract and Colorectum of HIV-Negative Men After Single and Multiple Dosing
Creators: name: Kashuba, Angela D. M.
name: Patterson, Kristine B.
name: Cohen, Myron S.
name: Greener, Benjamin N.
name: Adams, Jessica L.
name: Sykes, Craig S.
name: Dellon, Evan S.
name: Prince, Heather M. A.
name: Dumond, Julie B.
name: Madanick, Ryan D.
name: Shaheen, Nicholas J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: To describe first dose and steady-state pharmacokinetics (PK) of dolutegravir (DTG) in blood plasma (BP), seminal fluid (SF), colorectal tissue (RT), and rectal mucosal fluid (RF) of healthy HIV negative men.
Additional file 3 of Developmental disparities in sedentary time by period of the day among US youth: a cross-sectional study
Creators: name: Santiago-Rodríguez, María Enid
name: Chen, Jinsong
name: Pfeiffer, Karin A.
name: Marquez, David X.
name: Odoms-Young, Angela
name: Bustamante, Eduardo Esteban
Publisher: name: figshare
Year: 2022
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3: Table A3. Regressions of Sedentary Time on Each Weekday Period on Developmental Stage.
libyt: A Tool for In-Situ Parallel Analysis and its Scientific Applications
Creators: name: Tsai, Shin-Rong
name: Schive, Hsi-Yu
Publisher: name: Zenodo
Year: 2022
Subjects: data analysis

description: The size and scale of simulations have grown rapidly in order to solve larger physics problems and to render the data in a higher resolution. This resulted in bigger dataset in each step in simulations. Analytic tools have been developed to analyze and visualize these output datasets, but they suffer from having simulations to store the full datasets on disk first before further analyzing them. This may take up lots of disk space if we want to analyze the data in a high resolution time series. This also wastes lots of space storing unnecessary data, if we only need a small portion from them. We developed libyt to solve this problem. libyt is a C++ library for yt, that aims to make simulations able to use yt or other Python packages to analyze data arbitrarily in code runtime. We describe how libyt is built and demonstrate that it plays an important role in large simulations. We also show the advantage of using libyt and how it can be extended and connected to other analytic tools in the upcoming updates.
Hematologic, Hepatic, Renal, and Lipid Laboratory Monitoring After Initiation of Combination Antiretroviral Therapy in the United States, 2000–2010
Creators: name: Crane, Heidi M.
name: Taiwo, Babafemi O.
name: Koletar, Susan L.
name: Mathews, William C.
name: Ryscavage, Patrick
name: Mayer, Kenneth H.
name: Moore, Richard D.
name: Kahn, James
name: Zinski, Anne
name: Hunt, Peter
name: Cole, Stephen R.
name: Yanik, Elizabeth L.
name: Napravnik, Sonia
name: Eron, Joseph J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: We assessed laboratory monitoring following combination antiretroviral therapy (cART) initiation among 3,678 patients in a large US multi-site clinical cohort, censoring participants at last clinic visit, cART change, or three years. Median days (interquartile range) to first hematologic, hepatic, renal and lipid tests were 30 (18–53), 31 (19–56), 33 (20–59) and 350 (96–1106), respectively. At one year, approximately 80% received more than two hematologic, hepatic, and renal tests consistent with guidelines. However, only 40% received one or more lipid tests. Monitoring was more frequent in specific subgroups, likely reflecting better clinic attendance or clinician perception of higher susceptibility to toxicities.
Gate-Tunable Transmon Using Selective-Area-Grown Superconductor-Semiconductor Hybrid Structures on Silicon
Creators: name: Hertel, A.
name: Eichinger, M.
name: Andersen, L. O.
name: van Zanten, D. M. T.
name: Kallatt, S.
name: Scarlino, P.
name: Kringhøj, A.
name: Chavez-Garcia, J. M.
name: Gardner, G. C.
name: Gronin, S.
name: Manfra, M. J.
name: Gyenis, A.
name: Kjaergaard, M.
name: Marcus, C. M.
name: Petersson, K. D.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present a gate-voltage tunable transmon qubit (gatemon) based on planar InAs nanowires that are selectively grown on a high resistivity silicon substrate using III-V buffer layers. We show that low loss superconducting resonators with an internal quality of $2\times 10^5$ can readily be realized using these substrates after the removal of buffer layers. We demonstrate coherent control and readout of a gatemon device with a relaxation time, $T_{1}\approx 700\,\mathrm{ns}$, and dephasing times, $T_2^{\ast}\approx 20\,\mathrm{ns}$ and $T_{\mathrm{2,echo}} \approx 1.3\,\mathrm{μs}$. Further, we infer a high junction transparency of $0.4 - 0.9$ from an analysis of the qubit anharmonicity.
The role of community pharmacists as advisors on prescription medication
Creators: name: Gerrett, David
Publisher: name: University of Derby
Year: 1995
Subjects: community pharmacists
Pharmacy
prescription medication

description: This thesis describes the historical and functional evolution of British community pharmacists showing the succession of a compounding role by a supply function with incumbent bureaucracy. Development of a role as advisors on prescription medication is reviewed and the potential benefit explored by reviewing patients' lack of understanding about their medication following advice from general medical practitioners. Although ethical directives and specific guidance could be identified for the application and use of additional labels, little was found for provision of verbal advice. No comprehensive research was found to describe the prescription medication advisory role of community pharmacists. The present thesis primarily addresses this lack of knowledge. For a total of 651/2 days between June 1988 and February 1989 the discussions of twenty of twenty four randomly selected community pharmacists which involved prescription medication were tape recorded, transcribed and the circumstances observed. For half this time a poster advertising community pharmacists' advisory service was displayed. Verbal advice was provided by the community pharmacist to 473 of 3519 individuals involved with prescription medication. Two types of community pharmacists were identified, proactive and reactive. Irrespective of type, a constant level of requests for advice was noted. Overall, display of the poster was not associated with any significant effect on the quantity of advice; however, it was associated with changes in the nature of advice with greater emphasis on 'Specific problem' and 'Side effects' over 'What is prescribed' and 'What to do with it'. Although reiteration of the prescribers' directions and verbalising additional label warnings accounted for the majority of verbal advice, qualitative analysis revealed an element of independent judgement. The sociological literature on the professions provides an understanding for the observations. It is argued that guidance for verbal advice provided in the British National Formulary may facilitate community pharmacists' prescription medication advisory role.
High Levels of Antiretroviral Use and Viral Suppression Among Persons in HIV Care in the United States, 2010
Creators: name: Golden, Matthew R.
name: Mathews, W. Christopher
name: Kitahata, Mari M.
name: Mugavero, Michael J.
name: Crane, Heidi M.
name: Van Rompaey, Stephen E.
name: Dombrowski, Julia C.
name: Eron, Joseph J.
name: Moore, Richard D.
name: Martin, Jeffrey N.
name: Boswell, Stephen L.
name: Rodriguez, Benigno
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Contemporary data on patterns of antiretroviral therapy (ART) use in the U.S. are needed to inform efforts to improve the HIV care cascade.
Beam Squint-Aware Integrated Sensing and Communications for Hybrid Massive MIMO LEO Satellite Systems
Creators: name: You, Li
name: Qiang, Xiaoyu
name: Tsinos, Christos G.
name: Liu, Fan
name: Wang, Wenjin
name: Gao, Xiqi
name: Ottersten, Björn
Publisher: name: arXiv
Year: 2022
Subjects: subject: Information Theory (cs.IT)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The space-air-ground-sea integrated network (SAGSIN) plays an important role in offering global coverage. To improve the efficient utilization of spectral and hardware resources in the SAGSIN, integrated sensing and communications (ISAC) has drawn extensive attention. Most existing ISAC works focus on terrestrial networks and can not be straightforwardly applied in satellite systems due to the significantly different electromagnetic wave propagation properties. In this work, we investigate the application of ISAC in massive multiple-input multiple-output (MIMO) low earth orbit (LEO) satellite systems. We first characterize the statistical wave propagation properties by considering beam squint effects. Based on this analysis, we propose a beam squint-aware ISAC technique for hybrid analog/digital massive MIMO LEO satellite systems exploiting statistical channel state information. Simulation results demonstrate that the proposed scheme can operate both the wireless communications and the target sensing simultaneously with satisfactory performance, and the beam-squint effects can be efficiently mitigated with the proposed method in typical LEO satellite systems.
description: to appear in IEEE Journal on Selected Areas in Communications
Macroporous adsorptive resin-assisted enrichment of polyphenol from Psidium guajava leaves improved its in vitro antioxidant and anti-hemolytic properties
Creators: name: Umeoguaju, Francis Uchenna
name: Akaninwor, Joyce Oronne
name: Essien, Eka Bassey
name: Amadi, Benjamin Achor
name: Chukeze, Ezenwa James
name: Nwafor, Ifunanya Rosemary
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Hematology
subject: Plant Biology

description: Phytochemical analyses of guava leaf extracts, commonly applied in traditional medicine, revealed the presence of several bioactive polyphenols. In this study, we optimized the enrichment of total polyphenol from Guava leaf ethanolic extract (GEE) using six macroporous adsorptive resins (MAR) including AB8, D101, X5, ADS17, S400, and AD7. Also investigated are the contributions of adsorption time, extract concentration, pH, elution time, and eluent ethanol concentrations on the polyphenol enrichment potential of MAR. The antioxidant and anti-hemolytic properties of the crude and polyphenol-rich extracts were determined. Our results indicate that treatment of GEE extract with AB8 MAR at a concentration of 15 mg GEE/g resin, adsorption time of 45 min, elution time of 40 min, and eluent ethanol concentration of 50% (v/v) improved the flavonoids and phenol concentration of GEE by 2 and 2.5 folds respectively. The DPPH radical scavenging, ferric reducing ability of the plasma (FRAP), anti-hemolytic and anti-peroxidation activity of the resultant polyphenol-rich extracts improved by 1.5, 1.6, 1.4, and 1.88 folds respectively, when compared to the crude extract. Our work shows that the MAR-assisted enrichment operation is a rapid, feasible, and economical strategy for enriching bioactive polyphenols from guava leaf extracts.
HIV Testing and Counseling Leads to Immediate Consistent Condom Use Among South African Stable HIV-Discordant Couples
Creators: name: Delany-Moretlwe, Sinead
name: Bruyn, Guy De
name: Miller, William C.
name: Westreich, Daniel
name: Behets, Frieda
name: Rosenberg, Nora E.
name: Maman, Suzanne
name: Coetzee, David
name: Pettifor, Audrey E.
name: Kamupira, Mercy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Effective behavioral HIV prevention is needed for stable HIV-discordant couples at risk for HIV, especially those without access to biomedical prevention. This analysis addressed whether HIV testing and counseling (HTC) with ongoing counseling and condom distribution lead to reduced unprotected sex in HIV-discordant couples.
Interspecific protoplast fusion of atmospheric and room-temperature plasma mutants of Aspergillus generates an L-asparaginase hyper-producing hybrid with techno-economic benefits
Creators: name: Asitok, Atim
name: Ekpenyong, Maurice
name: Akwagiobe, Ernest
name: Asuquo, Marcus
name: Rao, Anitha
name: Ubi, David
name: Iheanacho, Juliet
name: Ikharia, Eloghosa
name: Antai, Agnes
name: Essien, Joseph
name: Antai, Sylvester
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Virology

description: The axenic culture of Aspergillus candidus (Asp-C) produced an anti-leukemic L-asparaginase while Aspergillus sydowii (Asp-S) produced the acrylamide-reduction type. Upon mutagenesis by atmospheric and room-temperature plasma (ARTP), their individual L-asparaginase activities improved 2.3-folds in each of Ile-Thr-Asp-C-180-K and Val-Asp-S-180-E stable mutants. Protoplast fusion of selected stable mutants generated fusant-09 with improved anti-leukemic activity, acrylamide reduction, higher temperature optimum and superior kinetic parameters. Submerged (SmF) and solid-state fermentation (SSF) types were compared; likewise batch, fed-batch and continuous fermentation modes; and fed-batch submerged fermentation was selected on the basis of impressive techno-economics. Fusant L-asparaginase was purified by PEG/Na+ citrate aqueous two-phase system and molecular exclusion chromatography to 69.96 and 146.21-fold, respectively, and characterized by molecular weight, specificity, activity and stability to chemical and physical agents. Michaelis–Menten kinetics, evaluated under optimum conditions gave Km, Vmax, Kcat, and Kcat/Km as 1.667 × 10−3 M, 1666.67 µmol min−1 mg−1 protein, 645.99 s−1 and 3.88 × 105 M−1 s−1 respectively. In-vitro cytotoxicity of HL-60 cell lines by fusant-09 L-asparaginase improved 3.00 and 18.71-folds from mutants Ile-Thr-Asp-C-180-K and Val-Asp-S-180-E, and from 5.73 and 32.55 from respective original strains. Free-radical scavenging and acrylamide reduction improvements were intermediate. Fusant-09 L-asparaginase is strongly recommended for sustainable economic anti-leukemic and food industry applications.
Additional file 4 of Developmental disparities in sedentary time by period of the day among US youth: a cross-sectional study
Creators: name: Santiago-Rodríguez, María Enid
name: Chen, Jinsong
name: Pfeiffer, Karin A.
name: Marquez, David X.
name: Odoms-Young, Angela
name: Bustamante, Eduardo Esteban
Publisher: name: figshare
Year: 2022
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 4: Table A4. Regressions of Sedentary Time During Each Weekend Period on Developmental Stage.
Word Embeddings for Automatic Equalization in Audio Mixing
Creators: name: Venkatesh, Satvik
name: Moffat, David
name: Miranda, Eduardo Reck
Publisher: name: arXiv
Year: 2022
Subjects: subject: Sound (cs.SD)
subject: Machine Learning (cs.LG)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: I.5.1; I.5.4

description: In recent years, machine learning has been widely adopted to automate the audio mixing process. Automatic mixing systems have been applied to various audio effects such as gain-adjustment, equalization, and reverberation. These systems can be controlled through visual interfaces, providing audio examples, using knobs, and semantic descriptors. Using semantic descriptors or textual information to control these systems is an effective way for artists to communicate their creative goals. In this paper, we explore the novel idea of using word embeddings to represent semantic descriptors. Word embeddings are generally obtained by training neural networks on large corpora of written text. These embeddings serve as the input layer of the neural network to create a translation from words to EQ settings. Using this technique, the machine learning model can also generate EQ settings for semantic descriptors that it has not seen before. We compare the EQ settings of humans with the predictions of the neural network to evaluate the quality of predictions. The results showed that the embedding layer enables the neural network to understand semantic descriptors. We observed that the models with embedding layers perform better than those without embedding layers, but still not as good as human labels.
description: 10 pages, 5 Figures, 3 tables; More experimental validation; Published in the Journal of the Audio Engineering Society
4Science & ORCID: the DSpace* ORCID integration
Creators: name: Bollini, Andrea
name: Lombardi, Corrado
Publisher: name: Zenodo
Year: 2022
Subjects: dspace
DSpace-CRIS
orcid
pid
interoperability

description: This presentation was delivered during the ORCID Team Retreat meeting in Italy (October 2022) to present the activities done by 4Science to benefit ORCID Members adopting the DSpace platform. 4Science, a leading contributor of DSpace, has developed the current ORCID integration for DSpace offering the ability to connect DSpace researcher profiles with ORCID, then push publications & projects information to the ORCID profile. DSpace, until its version 7.2 was only able to query the ORCID registry to lookup for authors. DSpace-CRIS instead, an open source extension of DSpace built and maintained by 4Science, provides since version 4 a full bi-directional integration with ORCID able to push & pull data via the member API. The DSpace governance, Steering & Leadership groups, set these new features as a high priority and 4Science donated what was done for ORCID integration in DSpace-CRIS adaption and ported such features to plain DSpace. These features are available in DSpace, starting from 7.3 version.
อุบัติการณ์และปัจจัยที่มีความสัมพันธ์กับการเกิดอาการไม่พึงประสงค์หลังรับวัคซีนไข้หวัดใหญ่ในบุคลากรของศูนย์วิชาการสาธารณสุข เขตสุขภาพที่ 9
Creators: name: พัชรภร  คอนจำนงค์
Publisher: name: สถาบันป้องกันควบคุมโรคเขตเมือง
Year: 2023
Subjects: อาการไม่พึงประสงค์ภายหลังการได้รับวัคซีน
โรคไข้หวัดใหญ่
ศูนย์วิชาการสาธารณสุข

description: วารสารสถาบันป้องกันควบคุมโรคเขตเมือง, 7, 2, 39-50
Massive MIMO with Dual-Polarized Antennas
Creators: name: Özdogan, Özgecan
name: Björnson, Emil
Publisher: name: arXiv
Year: 2022
Subjects: subject: Information Theory (cs.IT)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This paper considers a single-cell massive MIMO (multiple-input multiple-output) system with dual-polarized antennas at both the base station and users. We study a channel model that includes the key practical aspects that arise when utilizing dual-polarization: channel cross-polar discrimination (XPD) and cross-polar correlations (XPC) at the transmitter and receiver. We derive the achievable uplink and downlink spectral efficiencies (SE) with and without successive interference cancellation (SIC) when using the linear minimum mean squared error (MMSE), zero-forcing (ZF), and maximum ratio (MR) combining/precoding schemes. The expressions depend on the statistical properties of the MMSE channel estimator obtained for the dual-polarized channel model. Closed-form uplink and downlink SE expressions for MR combining/precoding are derived. Using these expressions, we propose power-control algorithms that maximize the uplink and downlink sum SEs under uncorrelated fading but can be used to enhance performance also with correlated fading. We compare the SEs achieved in dual-polarized and uni-polarized setups numerically and evaluate the impact of XPD and XPC conditions. The simulations reveal that dual-polarized setups achieve 40-60\% higher SEs and the gains remain also under severe XPD and XPC. Dual-polarized also systems benefit more from advanced signal processing that compensates for imperfections.
description: 15 pages, 9 figures. To appear in IEEE Transactions on Wireless Communications
title: Modelling crack nucleation in composite materials: a semi-analytical two-scale approach
Creators: name: Felger, Julian
Publisher: name: UNSPECIFIED
Year: 2020

description: The objective of this work is to provide an efficient semi-analytical approach for predicting crack onset at sharp notches, bi-material junctions and openings in fibre-reinforced laminates. On the one hand, this is achieved employing a complex potential approach that accurately captures stress concentrations and enables a precise calculation of generalised stress intensity factors. On the other hand, the method of matched asymptotic expansions is applied interpreting a newly nucleated crack as a small perturbation parameter within a singular perturbation problem. This methodology enables an efficient evaluation of the coupled stress and energy criterion forming a necessary and sufficient condition for fracture. Predictions relying on the asymptotic approach are validated against fully numerical reference data as well as experimental findings from literature.
Hormonal Contraceptive Use and Discontinuation Among HIV-Infected Women in Uganda and Zimbabwe
Creators: name: Kwok, Cynthia
name: Bengtson, Angela
name: Moyo, Precious
name: Salata, Robert A.
name: Byamugisha, Josaphat
name: Morrison, Charles S.
name: Chipato, Tsungai
name: Rwambuya, Sandra
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Hormonal contraception (HC) use by HIV-infected women has been identified by the WHO as important strategy for reducing vertical HIV transmission. Little is known about factors associated with HC discontinuation among HIV-infected women.
GIS and Feng Shui: Incorporation of Chinese Geomancy with GIS, demonstrated on Grahamstown West
Creators: name: Lech, James
name: McGregor, Gillian
name: Rowntree, Kate
name: Ya, Venerable Master Shih Man
name: Yun, Venerable Master Hsing
Publisher: name: figshare
Year: 2023
Subjects: Community planning
Regulatory planning and development assessment
Regional analysis and development
Land use and environmental planning
Design anthropology
Design for disaster relief
Design management
Ergonomics design
Data visualisation and computational (incl. parametric and generative) design
Radiation and matter
Theoretical quantum chemistry
Computational chemistry
Computational modelling and simulation in earth sciences
Earth and space science informatics
Geoscience data visualisation
Applied geophysics
Electrical and electromagnetic methods in geophysics
Climate change processes
Climatology
Surface water hydrology
Urban hydrology
Contaminant hydrology
Ecohydrology
Groundwater hydrology
Agricultural economics
Behavioural economics
Economic history
Health economics
Artificial life and complex adaptive systems
Modelling and simulation
Knowledge representation and reasoning
Quantum information, computation and communication
Quantum physics not elsewhere classified

description: The incorporation of Chinese Geomancy (Feng Shui) with GIS is a framework that separates the site analysis process into different models which are then incorporated and the interactions between them are studied. The models utilized in this project are environmental models (hydrology and topography), social-cultural models and infrastructure models, with each model containing several important factors. The demonstration identifies and organizes environmental factors within the framework that influence site analysis and auspicious design. By utilizing Feng Shui principles and their interpretations in measurable factors, this project demonstrates the incorporation of Feng Shui, GIS and contemporary environmental design theories in order to summarize essential environmental factors which operate in site analysis. The framework of these incorporated models may lead to a better understanding of the relationships between humankind and the natural environment thus enabling sustainable management practices. The aforementioned framework is implemented using a computer mapping information program, titled ArcView version, to accompany the discourse on the concepts and ideas of Feng Shui incorporated with GIS. ArcView assists a user to collect a wide range of information and select corresponding criteria in the early stages of design, providing a visual analysis in the form of GIS maps, based on the selected criteria and models. This project uses the town of Grahamstown in the Eastern Cape, South Africa, as the study area because of the availability of information and resources.
 This research was by the directive of: Venerable Master Shih Man Ya Venerable Master Hsing Yun Fo Guang Shan Nan Hua Temple (南華寺, Nanhua Si), Bronkhorstspruit, South Africa