cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Instrumented Footwear and Machine Learning for Gait Analysis and Training
Creators: Prado de la Mora, Jesus Antonio
Publisher: name: Columbia University
Year: 2021
Subjects: Robotics
Footwear--Design and construction
Gait in humans--Analysis
Parkinson's disease
Neural networks (Computer science)--Industrial applications

description: Gait analysis allows clinicians and researchers to quantitatively characterize the kinematics and kinetics of human movement. Devices that quantify gait can be either portable, such as instrumented shoes, or non-portable, such as motion capture systems and instrumented walkways. There is a tradeoff between these two classes of systems in terms of portability and accuracy. However, recent computer advances allow for the collection of meaningful data outside of the clinical setting. In this work, we present the DeepSole system combined with the different neural network models. This system is a fully capable to characterize the gait of the individuals and provide vibratory feedback to the wearer. Thanks to the flexible construction and its wireless capabilities, it can be comfortably worn by wide arrange of people, both able-bodied and people with pathologies that affect their gait. It can be used for characterization, training, and as an abstract sensor to measure human gait in real-time. Three neural network models were designed and implemented to map the sensors embedded in the DeepSole system to gait characteristics and events. The first one is a recurrent neural network that classifies the gait into the correct gait phase of the wearer. This model was validated with data from healthy young adults and children with Cerebral Palsy. Furthermore, this model was implemented in real-time to provide vibratory feedback to healthy young adults to create temporal asymmetry on the dominant side during regular walking. During the experiment, the subjects who walked had an increased stance time on both sides, but the dominant side was affected more. The second model is encoder-decoder recurrent neural network that maps the sensors into current gait cycle percentage. This model is useful to provide continuous feedback that is synchronized to the gait. This model was implemented in real-time to provide vibratory feedback to six muscle groups used during regular walking. The effects of the vibration were analyzed. It was found that depending on the feedback, the subjects changed their spatial and temporal gait parameters. The third model uses all the sensors in the instrumented footwear to identify a motor phenomenon called freezing of gait in patients with Parkinson’s Disease. This phenomenon is characterized by transient periods, usually lasting for several seconds, in which attempted ambulation is halted. The model has better performance than the state-of-the-art and does not require any pre-processing. The DeepSole system when used in conjunction with the presented models is able to characterize and provide feedback in a wide range of scenarios. The system is portable, comfortable, and can accommodate a wide range of populations who can benefit from this wearable technology.
Additional file 6 of CLK1/SRSF5 pathway induces aberrant exon skipping of METTL14 and Cyclin L2 and promotes growth and metastasis of pancreatic cancer
Creators: name: Chen, Shi
name: Yang, Can
name: Wang, Zu-Wei
name: Hu, Jian-Fei
name: Pan, Jing-Jing
name: Liao, Cheng-Yu
name: Zhang, Jia-Qiang
name: Chen, Jiang-Zhi
name: Huang, Yi
name: Huang, Long
name: Zhan, Qian
name: Tian, Yi-Feng
name: Shen, Bai-Yong
name: Wang, Yao-Dong
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 6: Figure S5. CLK1-mediated SRSF5 phosphorylation on Ser250 contributed to the malignant behaviors of pancreatic cancer cells. (A-E) BxPC-3 cells were infected with control lentivirus, or lentivirus expressing wild type (WT)/mutated (S250MU)/phosphorylated (S250P) SRSF5. The cell proliferation ability (A, B), colony formation ability (C), and migration and invasion ability (D, E) of the indicated stable cells were evaluated. (F-J) PANC-1 cells were infected with control lentivirus or lentivirus overexpressing CLK1 or lentivirus overexpressing CLK1 together with shSRSF5. The cell proliferation ability (F, G), colony formation ability (H), and migration and invasion ability (I, J).The stable cells were infected with control lentivirus, or lentivirus expressing wild type (WT)/mutated (S250MU)/phosphorylated (S250P) SRSF5 were simultaneous treatment with TG003 (K–O)were evaluated. The cell proliferation ability (K, L), colony formation ability (M), and migration and invasion ability (N, O). (P)The quantification of the results of Fig. 5B. (Q, R)The quantification of the results of Fig. 5K. n = 3 for each group; data are shown as mean ± SD from three independent experiments.*P < 0.05; **P < 0.01; ***P < 0.001, between the indicated groups.
Classical Spacetime from Quantum Gravity
Creators: name: Kim, Sang Pyo
Publisher: name: arXiv
Year: 1996
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We show how classical spacetime emerges from quantum gravity through the study of a quantum FRW cosmological model coupled to a free massive scalar field using a new asymptotic expansion method of the Wheeler-DeWitt equation. It is shown that the coherent states of the nonadiabatic basis of a particular generalized invariant give rise to the quantum back reaction of matter field proportional to classical energy and the Einstein-Hamilton-Jacobi with matter becomes equivalent to the classical Einstein equation.
description: 10 pages, ReVTeX, No Figures
Painleve III Equation and Bianchi VII_0 Model
Creators: name: Manojlovic, N.
name: Mikovic, A.
Publisher: name: arXiv
Year: 1999
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We examine the reduced phase space of the Bianchi VII_0 cosmological model, including the moduli sector. We show that the dynamics of the relevant sector of local degrees of freedom is given by a Painleve III equation. We then obtain a zero-curvature representation of this Painleve III equation by applying the Belinskii-Zakharov method to the Bianchi VII_0 model.
description: 30 pages, some typos corrected
title: Inula verbascifolia (Willd.) Hausskn.
Creators: name: :None
Publisher: name: Universitätsbibliothek
Year: 2009
Subjects: subject: Digitale Pflanzenbilder : Sammlung Dietmar Brandes
subject: 580

description: Pflanzensammlung Dietmar Brandes: Digitale Pflanzenbilder
SHOYIM BOʻTAYEVNING "HAYKAL" HIKOYASIDA BADIIY SHARTLILIK
Creators: name: Orazbaeva, Asal
name: Abdullayev, X.
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqolda  Shoyim Boʻtayevning “Haykal” hikoyasi tahlil qilinar ekan, jamiyatdagi ayrim illatlarni qattiq tanqid ostiga olgani haqida soʻz yuritiladi. Yana yozuvchining ijodiy faoliyati haqida toʻxtab oʻtiladi.
Apprentices and masters - the transmission of ancient goldsmith techniques
Creators: name: Pacini, Alessandro
Publisher: name: Substantia
Year: 2019

description: A historical overview from Sumerians to the present day on the goldsmith’s craft following two lines: the apprenticeship in the guilds and the ethical and religious value of gold working.
description: Substantia, Vol 3 No 1 Suppl. (2019)
Figure S2 from Aggression and discrimination among closely versus distantly related species of Drosophila
Creators: name: Gupta, Tarun
name: Howe, Sarah E.
name: Zorman, Marlo L.
name: Lockwood, Brent L.
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: Distantly related species pairs preferentially targeted aggression at conspecifics. Shown are frequency histograms of heterospecific (orange) and conspecific (blue) lunge counts of distantly related species pairs. Focal species is the aggressor that lunges on itself or the non-focal species (focal-nonfocal), with the same species name abbreviations as in Table 1. Vertical dashed lines indicate mean lunge counts. Ratio of mean lunge counts (RL; heterospecific:conspecific), number of aggression trials (N), and significance of the difference between the distributions of lunge counts based on the z-test (P) are shown in the upper right of each panel.
Insulin Regulation of Reverse Cholesterol Transport
Creators: Lee, Samuel
Publisher: name: Columbia University
Year: 2019
Subjects: Nutrition
Biology
High density lipoproteins--Metabolism
Insulin resistance
Cholesterol

description: Insulin resistance and type 2 diabetes are pathogenetically linked to increased risk of cardiovascular disease. While insulin resistance is defined by a dysregulation in hepatic insulin signaling, it is unclear how this impairment relates to the development of cardiovascular disease. Recently, there has been evidence showing that in insulin resistant individuals, cardiovascular disease is associated with a defect in reverse cholesterol transport – the cardioprotective process by which excess cholesterol is removed from the periphery, and returned to the liver for biliary excretion. Reverse cholesterol transport is facilitated by high-density lipoprotein (HDL) metabolism. Thus, malfunction in HDL turnover during reverse cholesterol transport may contribute to the buildup of atherosclerotic plaques, and subsequent cardiovascular disease in insulin resistant individuals. In this thesis, we seek to establish a better understanding of HDL metabolism and reverse cholesterol transport, as they relate to key transcription factors that mediate hepatic insulin signaling, namely the insulin-repressible forkhead transcription factors, FoxO1, FoxO3, and FoxO4 (FoxOs). We demonstrate that mice with liver-specific triple FoxO knockout (L-FoxO1,3,4) have increased HDL-cholesterol (HDL-C), associated with decreased expression of HDL-C clearance factors, scavenger receptor class B type I (SR-BI) and hepatic lipase, and defective selective uptake of HDL-cholesteryl ester by the liver. As such, we uncover a novel mechanism by which HDL-mediated reverse cholesterol transport to the liver is regulated by the hepatic insulin-->FoxO signaling pathway.
Drosophila apicisetae Hardy 1965
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila apicisetae

description: Drosophila apicisetae Hardy, 1965
Distribution: Endemic: Hawaii
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 14, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841
title: Iochroma cyaneum (Lindl.) M. L. Green
Creators: name: :None
Publisher: name: Universitätsbibliothek
Year: 2009
Subjects: subject: Digitale Pflanzenbilder : Sammlung Dietmar Brandes
subject: 580

description: Pflanzensammlung Dietmar Brandes: Digitale Pflanzenbilder
Institutionalizing Citizenship Participation: The Role of NGOs in Democratizing Land Security in Phnom Penh
Creators: Baum, Josie L. R.
Publisher: name: Columbia University
Year: 2012
Subjects: Non-governmental organizations
Land use--Planning
Land tenure

description: As Phnom Penh is developed as the flagship city of Cambodia, increasingly once uncontested land parcels are subject to land grabs and speculative investment. This has brought to the fore fundamental and persistent inequalities in the country, highlighting the opacity of its land rights institutions. This paper attempts to break-down the reality of the landlessness crisis in Cambodia, unpacking the political, economic and social forces influencing the outcomes of land disputes. Much research has critically analyzed the role and form of popular participation in development. This thesis studies how the normative stance of non-governmental organizations as facilitators of participation in development trajectories translates into support for those excluded by the dominant land rights institutions; those groups vulnerable to unplanned landlessness. What is the potential for non-governmental organizations to optimize such participation to address extreme inequalities in land rights by translating it into citizenship for vulnerable communities? How is this affected by prevailing aid paradigms and state activity? In the Cambodian context, determinants of aid-flows must recognize that failures in the land market are largely due to the state itself, and therefore re-frame their policies to emphasize the role of non-state actors in delivering land security.
Topological Feature Vectors for Chatter Detection in Turning Processes
Creators: name: Yesilli, Melih C.
name: Khasawneh, Firas A.
name: Otto, Andreas
Publisher: name: arXiv
Year: 2019
Subjects: subject: Signal Processing (eess.SP)
subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Machining processes are most accurately described using complex dynamical systems that include nonlinearities, time delays, and stochastic effects. Due to the nature of these models as well as the practical challenges which include time-varying parameters, the transition from numerical/analytical modeling of machining to the analysis of real cutting signals remains challenging. Some studies have focused on studying the time series of cutting processes using machine learning algorithms with the goal of identifying and predicting undesirable vibrations during machining referred to as chatter. These tools typically decompose the signal using Wavelet Packet Transforms (WPT) or Ensemble Empirical Mode Decomposition (EEMD). However, these methods require a significant overhead in identifying the feature vectors before a classifier can be trained. In this study, we present an alternative approach based on featurizing the time series of the cutting process using its topological features. We first embed the time series as a point cloud using Takens embedding. We then utilize Support Vector Machine, Logistic Regression, Random Forest and Gradient Boosting classifier combined with feature vectors derived from persistence diagrams, a tool from persistent homology, to encode chatter's distinguishing characteristics. We present the results for several choices of the topological feature vectors, and we compare our results to the WPT and EEMD methods using experimental turning data. Our results show that in two out of four cutting configurations the TDA-based features yield accuracies as high as 97%. We also show that combining Bezier curve approximation method and parallel computing can reduce runtime for persistence diagram computation of a single time series to less than a second thus making our approach suitable for online chatter detection.
description: Implementations of parallel computing and Bezier curve approximation for persistence diagram computation are added into the manuscript. Abstract and results section are updated with respect to the results obtained from persistence diagrams computed with Bezier approximation
Additional file 9 of CLK1/SRSF5 pathway induces aberrant exon skipping of METTL14 and Cyclin L2 and promotes growth and metastasis of pancreatic cancer
Creators: name: Chen, Shi
name: Yang, Can
name: Wang, Zu-Wei
name: Hu, Jian-Fei
name: Pan, Jing-Jing
name: Liao, Cheng-Yu
name: Zhang, Jia-Qiang
name: Chen, Jiang-Zhi
name: Huang, Yi
name: Huang, Long
name: Zhan, Qian
name: Tian, Yi-Feng
name: Shen, Bai-Yong
name: Wang, Yao-Dong
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 9: Figure S9. Aberrant alternative splicing of METTL14△exon10 and CyclinL2△exon6.3 possessed prognostic values for PDAC patients in external corhort.
A Study of the adult learning experiences of Peruvian single women who migrated to Australia in the late 1960s and early 1970s
Creators: name: Becerra, Flor
Publisher: name: Australian Catholic University
Year: 2000

description: This thesis constitutes a study of the migration, settlement and adult learning experiences of single Peruvian women who migrated to Australia between the 1960s and 1970s. As relevant background, matters related to the migration of women to Australia generally throughout this country's modern history are also examined. This study aims to contribute to the knowledge of history and the knowledge of adult education. The specific goal is to highlight the migration and settlement learning experiences of single Peruvian women as well as exploring aspects of the adult learning strategies that they have put in place in the course of their new life structure in Australia. The participants' decisions to migrate cannot be seen in isolation but rather as resulting from all or some of their life experiences leading to that decision and their own places in society. Accordingly this research recognises the importance of analysing the participants' narratives of their lives prior to that point and the period since and by so doing, acknowledge the basis of many of the decisions of early adulthood which set each of them on the path to change and learning. The stories of six Peruvian women, who migrated to Australia in the specified period, are presented using in-depth interviews in an unstructured format. Analysed from a feminist theory perspective, their narratives are examined as discursive productions which provide valuable insights into the social order of society and how each person found meaning within the discourses available to them. Additionally interviews were conducted with a number of immigration officers in Australia. Being centred upon the experiences of the women the thesis has been influenced by the ideas of several writers and thinkers on the subject including (but not limited to) John Dewey a 20th century adult education philosopher and his concept of 'lifelong learning', Jack Mezirow and his work on learning as 'transformative and emancipatory' and Jurgen Habermas' 'categories of enquiry'.
Hydrogeological site characterization in an acid rock drainage management program
Creators: name: Edwards, D. A.
name: Lawrence, Richard W.
Publisher: name: The University of British Columbia
Year: 2009

description: Surface and subsurface hydrological processes play important roles in the flushing and transport of acid rock drainage. A thorough understanding of the hydrogeologic regime at proposed mine sites and sites generating acid rock drainage is therefore necessary prior to the initiation of an ARD management program. The hydrogeological site characterization should establish the regional hydrogeological setting, local baseline groundwater quality, the local hydrogeologic regime geometry, hydrogeologic parameters of hydrostratigraphic units and site specific flow conditions. The site characterization involves a regional study, the site investigation and site groundwater flow assessment. Available hydrogeological data from the abandoned Mount Washington Mine located on Vancouver Island will be reviewed and the site will be used as an example to demonstrate the importance of groundwater in ARD flushing and transport. The mine was in operation through the mid-1960's. Acidic rock drainage and associated elevated copper concentrations generated in the North Pit of the site have been implicated in fishery losses in the Tsolum River. Strong hydrogeological controls on ARD flushing and transport have been identified but the hydrogeologic regime of the site is still not well understood.
Drosophila waddingtoni Basden 1976
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila waddingtoni

description: Drosophila waddingtoni Basden, 1976
 Synonyms: Drosophila disticha Hardy, 1965
Distribution: Endemic: Hawaii, Maui, Molokai, Lanai
 Additional References: Craddock et al. (2018); Hardy (1965); Heed (1968); Lapoint et al. (2009, 2011); Mangan (1978); O’Grady et al. (2011); O’Grady & Zilversmit (2004); Stark & O’Grady (2010); Takada (1966); Throckmorton (1966)
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 20, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841
Variation of G, $Λ_{(4)}$ and Vacuum Energy From Brane-World Models
Creators: name: de Leon, J. Ponce
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In brane-world theory in five dimensions, the bulk metric is usually written in gaussian coordinates, where $g_{4μ} = 0$ and $g_{44} = - 1$. However, the choice $g_{44} = - 1$ is an external condition, not a requirement of the field equations. In this paper we study the consequences of having $g_{44} = εΦ^2$, where $ε= \pm 1$ and $Φ$ is a scalar function varying with time, $\dotΦ \neq 0$. This varying field entails the possibility of variable fundamental physical "constants". These variations are different from those predicted in scalar-tensor and multidimensional theories. We solve the five-dimensional equations for a {\em fixed} brane and use the brane-world paradigm to determine the fundamental parameters in the theory, which are the vacuum energy $σ$, the gravitational coupling $G$ and the cosmological term $Λ_{(4)}$. We present specific models where these physical quantities are variable functions of time. Different scenarios are possible but we discuss with some detail a model for which $\dot{G}/G \sim H$ and $Λ_{(4)} \sim H^2$, which seems to be favored by observations. Our results are not in contradiction to previous ones in the literature. In particular, to those where the brane is described as a domain wall moving in a static $Sch-AdS$ bulk. Indeed these latter models in RS scenarios describe the same spacetime as other solutions (with fixed brane) in gaussian coordinates with $\dotΦ = 0 $. We conclude that the introduction of a time-varying $Φ$ in brane-world theory yields a number of models that show variation in the fundamental physical "constants" and exhibit reasonable physical properties.
description: In version 2 an error noticed by the author is fixed, and the corresponding changes are made. Version 3 is identical to v2, except for a couple of typos corrected. V3 will appear in Mod. Phys. Lett. A
The Inevitability of Sphalerons in Field Theory
Creators: name: Manton, N. S.
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The topological structure of field theory often makes inevitable the existence of stable and unstable localised solutions of the field equations. These are minima and saddle points of the energy. Saddle point solutions occurring this way are known as sphalerons, and the most interesting one is in the electroweak theory of coupled W, Z and Higgs bosons. The topological ideas underpinning sphalerons are reviewed here.
description: 18 pages, 5 figures. Based on Lecture at Royal Society Scientific Discussion Meeting: Topological Avatars of New Physics, 4-5 March 2019
Integer programming techniques for Polynomial Optimization
Creators: Munoz, Gonzalo
Publisher: name: Columbia University
Year: 2017
Subjects: subject: Operations research
subject: Mathematics
subject: FOS: Mathematics
subject: Polynomials
subject: Integer programming
subject: Mathematical optimization

description: Modern problems arising in many domains are driving a need for more capable, state-of-the-art optimization tools. A sharp focus on performance and accuracy has appeared, for example, in science and engineering applications. In particular, we have seen a growth in studies related to Polynomial Optimization: a field with beautiful and deep theory, offering flexibility for modeling and high impact in diverse areas.
      The understanding of structural aspects of the feasible sets in Polynomial Optimization, mainly studied in Real Algebraic Geometry, has a long tradition in Mathematics and it has recently acquired increased computational maturity, opening the gate for new Optimization methodologies to be developed. The celebrated hierarchies due to Lasserre, for example, emerged as good algorithmic templates. They allow the representation of semi-algebraic sets, possibly non-convex, through convex sets in lifted spaces, thus enabling the use of long-studied Convex Optimization methods. Nonetheless, there are some computational drawbacks for these approaches: they often rely on possibly large semidefinite programs, and due to scalability and numerical issues associated with SDPs, alternatives and complements are arising.

      In this dissertation, we will explore theoretical and practical Integer-Programming-based techniques for Polynomial Optimization problems. We first present a Linear Programming relaxation for the AC-OPF problem in Power Systems, a non-convex quadratic problem, and show how such relaxation can be used to develop a tractable MIP-based algorithm for the AC Transmission Switching problem. From a more theoretical perspective, and motivated by the AC-OPF problem, we study how sparsity can be exploited as a tool for analysis of the fundamental complexity of a Polynomial Optimization problem, by showing LP formulations that can efficiently approximate sparse polynomial problems. Finally, we show a computationally practical approach for constructing strong LP approximations on-the-fly, using cutting plane approaches. We will show two different frameworks that can generate cutting planes, which are based on classical methods used in Mixed-Integer Programming.
      Our methods mainly rely on the maturity of current MIP technology; we believe these contributions are important for the development of manageable approaches to general Polynomial Optimization problems.
Drosophila ancyla Hardy 1965
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila ancyla

description: Drosophila ancyla Hardy, 1965
Distribution: Endemic: Maui
 Additional References: Hardy & Kaneshiro (1979); Heed (1968); O’Grady et al. (2011); Throckmorton (1966)
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 17, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841
Integrated CMOS Polymerase Chain Reaction Lab-on-chip
Creators: Norian, Haig
Publisher: name: Columbia University
Year: 2014
Subjects: Molecular diagnosis
Labs on a chip
Microelectromechanical systems
Polymerase chain reaction
Electrical engineering

description: Considerable effort has recently been directed toward the miniaturization of quantitative-polymerase-chain-reaction [QPCR] instrumentation in an effort to reduce both cost and form factor for point-of-care applications.  Notable gains have been made in shrinking the required volumes of PCR reagents, but resultant prototypes retain their bench-top form factor either due to heavy heating plates or cumbersome optical sensing instrumentation.   In this thesis, we describe the use of complementary-metal-oxide semiconductor (CMOS) integrated circuit (IC) technology to produce a fully integrated qPCR lab-on-chip.  Exploiting a 0.35-µm high-voltage CMOS process, the IC contains all of the key components for performing qPCR.  Integrated resistive heaters and temperature sensors regulate the surface temperature of the chip to 0.45°C.  Electrowetting-on-dielectric microfluidic pixels are actively driven from the chip surface, allowing for droplet generation and transport down to volumes of less than 1.2 nanoliters. Integrated single-photon avalanche diodes [SPAD] are used for fluorescent monitoring of the reaction, allowing for the quantification of target DNA with more than four-orders-of-magnitude of dynamic range with sensitivities down to a single copy per droplet.  Using this device, reliable and sensitive real-time proof-of-concept detection of Staphylococcus aureus (S. aureus) is demonstrated.
Phase Space Derivation of a Variational Principle for One Dimensional Hamiltonian Systems
Creators: name: Benguria, R. D.
name: Depassier, M. C.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We consider the bifurcation problem u'' + λu = N(u) with two point boundary conditions where N(u) is a general nonlinear term which may also depend on the eigenvalue λ. A new derivation of a variational principle for the lowest eigenvalue λis given. This derivation makes use only of simple algebraic inequalities and leads directly to a more explicit expression for the eigenvalue than what had been given previously.
description: 2 pages, Revtex, no figures
Energy-efficient techniques for combating the influence of reactive jamming using Non-Orthogonal Multiple Access and Distributed Antenna Systems
Creators: name: Farah, Joumana
name: Akiki, Jacques
name: Simon, Eric Pierre
Publisher: name: arXiv
Year: 2019
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The aim of this work is to propose new approaches for maximizing the energy efficiency of downlink 5G mobile communication systems, in the presence of a reactive jammer. The concepts of non-orthogonal multiple access (NOMA) and distributed antenna systems (DAS) are exploited to devise joint subband, power and antenna assignment techniques, so as to guarantee a certain quality of service (QoS) to users. Also, the scheduler relies on jamming statistics, observed at the end of each timeslot, to perform resource allocation based on the prediction of the jammer behavior over the next timeslot. A particular care is given, in the proposed techniques, to maintain a moderate complexity at the receiver level, and to limit the number of active RRHs (remote radio heads) in the cell. Simulation results show that a proper combination of NOMA with DAS can allow a significant enhancement of the system robustness to jamming, with respect to centralized antenna systems and orthogonal multiple access.
description: Accepted conference paper
Instructional Demonstrations are More Effective Than Consequences Alone for Children with Naming
Creators: Hranchuk, Kieva Sofia
Publisher: name: Columbia University
Year: 2016
Subjects: subject: Child development--Psychological aspects
subject: Child development
subject: Learning
subject: Learning, Psychology of
subject: Psychology
subject: FOS: Psychology
subject: Education
subject: Developmental psychology

description: In Experiment 1, a demonstration study, I first tested the number of exposures to incidental learning conditions (naming experiences) required for 4 typically developing preschool-aged males with the naming developmental cusp and capability, to master the names of novel 2D non-contrived stimuli (i.e., symbols for pound, lira, tilde, percent, omega, and ampersand). Each stimulus required 1 to 5 naming experiences to master as both listener and speaker (with more needed for the speaker responses). Prior research found that without the naming cusp, children did not learn from instructional demonstrations presented before the opportunity to respond, however, following the establishment of naming, they could. In Experiment 2, using an ABAB (BABA) reversal design counterbalanced across two dyads, I compared the same participants’ rates of learning under two different instructional methods: 1) instructional demonstrations presented before the opportunity to respond through learn units (IDLUs) and 2) standard learn unit instruction (SLUs). The children learned at an accelerated rate (cumulative correct responses to mastery of objectives) under the IDLU conditions and with between 30% and 50% accuracy on first presentations following a model. The IDLU condition was more efficient (fewer trials to criteria). In this case, the degree of superiority for IDLUs, compared to SLUs alone for children with naming was tested for the first time in Experiment 2. These findings, together with prior findings, suggest more effective teaching procedures for children with the developmental cusp and capability of naming.
Nonperturbative solutions for canonical quantum gravity: an overview
Creators: name: Ezawa, Kiyoshi
Publisher: name: arXiv
Year: 1996
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper we will make a survey of solutions to the Wheeler-Dewitt equation which have been found up to now in Ashtekar's formulation for canonical quantum gravity. Roughly speaking they are classified into two categories, namely, Wilson-loop solutions and topological solutions. While the program of finding solutions which are composed of Wilson loops is still in its infancy, it is expected to be developed in the near future. Topological solutions are the only solutions at present which we can give their interpretation in terms of spacetime geometry. While the analysis made here is formal in the sense that we do not deal with rigorously regularized constraint equations, these topological solutions are expected to exist even in the fully regularized theory and they are considered to yield vacuum states of quantum gravity. We also make an attempt to review the spin network states as intuitively as possible. In particular, the explicit formulae for two kinds of measures on the space of spin network states are given.
description: 78 pages Latex, four figures included as eps-files.(References added, some minor changes made in subsections 1.4, 3.2 and 7.3.)
Effect of Values and Technology Use on Exercise: Implications for Personalized Behavior Change Interventions
Creators: name: Mejova, Yelena
name: Kalimeri, Kyriaki
Publisher: name: arXiv
Year: 2019
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: Technology has recently been recruited in the war against the ongoing obesity crisis; however, the adoption of Health & Fitness applications for regular exercise is a struggle. In this study, we present a unique demographically representative dataset of 15k US residents that combines technology use logs with surveys on moral views, human values, and emotional contagion. Combining these data, we provide a holistic view of individuals to model their physical exercise behavior. First, we show which values determine the adoption of Health & Fitness mobile applications, finding that users who prioritize the value of purity and de-emphasize values of conformity, hedonism, and security are more likely to use such apps. Further, we achieve a weighted AUROC of .673 in predicting whether individual exercises, and we also show that the application usage data allows for substantially better classification performance (.608) compared to using basic demographics (.513) or internet browsing data (.546). We also find a strong link of exercise to respondent socioeconomic status, as well as the value of happiness. Using these insights, we propose actionable design guidelines for persuasive technologies targeting health behavior modification.
Integrated Circuit Design for Miniaturized, Trackable, Ultrasound Based Biomedical Implants
Creators: Zhang, Yihan
Publisher: name: Columbia University
Year: 2020
Subjects: Electrical engineering
Biomedical engineering
Implants, Artificial
Ultrasonics in medicine
Integrated circuits

description: This thesis focuses on the design of an ultrasonography compatible implantable sensor platform, as a novel approach that implements a miniaturized, battery-less, real-time trackable parallel biosensing system. In addition to the frontend circuit, a sub-nW fully integrated pH sensor is designed in a way that can be easily integrated with the proposed sonography-compatible sensor platform. Combining the two integrated circuits together, the whole system will be able to map in vivo physiological information acquired from a distributed set of sensors on top of the ultrasound movie, leading to the idea envisioned as “augmented ultrasonography”. Implemented in a 0.18 μm technology, an ultrasound power and data frontend circuit is designed to enable medical sensing implants to operate in an ultrasonography compatible way. When placed within the field of view of an imaging transducer, the frontend circuit harvests the power through a piece of piezo crystal from a minimally modified brightness-mode (B-mode) ultrasound imaging process that is commonly adopted in modern medical practices. The implant can also establish bi-directional data communication channels with the imaging transducer, allowing data to be transmitted in a way synchronized to the frame rate of the B-mode film. The design of the circuit is made possible by a combination of ultra-low-power circuit techniques and novel frontend circuit topologies, as imaging ultrasound waves in the form of short pulses with extremely low duty cycle poses challenges that has not previously seen in other implantable sensor systems. The proposed prototype achieves a total area of 0.6mm² for the integrated circuit (IC), as well as 71mm theoretical maximum implantable depth (up to 40 mm is verified experimentally). These two together give opportunities for this design to become the next generation solution for deep-tissue bio-sensing implants. Realized using the same 0.18 μm technology, the fully integrated pH sensor is designed to deliver accurate pH readouts, at a reasonable speed of 1 sample per second, while consuming only 0.72 nW of power. Using an ion-sensitive field effect transistor (ISFET) and reference field effect transistor pair (REFET), the IC requires minimum additional post fabrication to deliver 10-bit resolution pH readouts at an end-to-end sensitivity of 65.8 LSB/pH. When working as a standalone device, this work advances the state-of-the-art of ISFET based pH sensor design. With an addition of 0.46 mm² of area, it is possible to integrate it with the ultrasound sonography compatible implant platform. This potential integration will further advance the vision of the augmented ultrasonography: real-time display of physiological information in a B-mode film, with the help from a distributed bio-sensor system for deep-tissue physiology monitoring.
The characterization of hydrologic properties and moisture migration pathways of a waste rock pile
Creators: name: Herasymuik, G. M.
name: Wilson, G. Ward
name: Barbour, S. Lee
name: Smith, Troy
Publisher: name: The University of British Columbia
Year: 2009

description: A multiphase research program has been initiated on a large waste rock pile which has undergone partial excavation. The focus of the research is to define the distribution of moisture migration pathways in the waste rock and to develop a conceptual model of the heat and mass transfer processes within the pile. The first phase of the research program was conducted simultaneously with the excavation process. This phase included a field logging and sampling program of exposed waste rock from numerous test pits. The test pits were excavated along predetermined transect lines established on the benches of the waste rock pile which were exposed during the excavation process. Phase I included visually logging the exposed rock and insitu measurements of matric suction, temperature, relative humidity and water content. Samples of each waste rock unit described in phase I were obtained for further analysis. The second phase of research includes a laboratory testing program to determine saturated and unsaturated hydraulic and thermal properties of the rock. The properties being measured include grainsize, porosity, moisture retention characteristics, saturated hydraulic and thermal conductivity and specific heat capacity. In summary this paper outlines the research program to date and discusses the initial findings of the field program.
Drosophila fundita Hardy 1965
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila fundita

description: Drosophila fundita Hardy, 1965
Distribution: Endemic: Maui, Molokai, Lanai
 Additional References: Hardy & Kaneshiro (1979); Heed (1968); O’Grady et al. (2011); Throckmorton (1966)
Notes: Nishida (2002) reports this species from Hawaii
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 18, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841
Integrated Self-Interference Cancellation for Full-Duplex and Frequency-Division Duplexing Wireless Communication Systems
Creators: Zhou, Jin
Publisher: name: Columbia University
Year: 2017
Subjects: Wireless communication systems--Design and construction
Electrical engineering
Wireless communication systems

description: From wirelessly connected robots to car-to-car communications, and to smart cities, almost every aspect of our lives will benefit from future wireless communications. While promise an exciting future world, next-generation wireless communications impose requirements on the data rate, spectral efficiency, and latency (among others) that are higher than those for today's systems by several orders of magnitude.

      Full-duplex wireless, an emergent wireless communications paradigm, breaks the long-held assumption that it is impossible for a wireless device to transmit and receive simultaneously at the same frequency, and has the potential to immediately double network capacity at the physical (PHY) layer and offers many other benefits (such as reduced latency) at the higher layers. Recently, discrete-component-based demonstrations have established the feasibility of full-duplex wireless. However, the realization of integrated full duplex radios, compact radios that can fit into smartphones, is fraught with fundamental challenges. In addition, to unleash the full potential of full-duplex communication, a careful redesign of the PHY layer and the medium access control (MAC) layer using a cross-layer approach is required.

      The biggest challenge associated with full duplex wireless is the tremendous amount of transmitter self-interference right on top of the desired signal. In this dissertation, new self-interference-cancellation approaches at both system and circuit levels are presented, contributing towards the realization of full-duplex radios using integrated circuit technology. Specifically, these new approaches involve elimination of the noise and distortion of the cancellation circuitry, enhancing the integrated cancellation bandwidth, and performing joint radio frequency, analog, and digital cancellation to achieve cancellation with nearly one part-per-billion accuracy.

      In collaboration with researchers at higher layers of the stack, a cross-layer approach has been used in our full-duplex research and has allowed us to derive power allocation algorithms and to characterize rate-gain improvements for full-duplex wireless networks. To enable experimental characterization of full-duplex MAC layer algorithms, a cross-layered software-defined full-duplex radio testbed has been developed. In collaboration with researchers from the field of micro-electro-mechanical systems, we demonstrate a multi-band frequency-division duplexing system using a cavity-filter-based tunable duplexer and our integrated widely-tunable self-interference-cancelling receiver.
BETTSI - Basic Evolutionary Tree-Thinking Skills Instrument
Creators: name: Jenkins, Kristin
name: Mead, Louise
name: Baum, David
name: Daniel, Kristy
name: Bucklin, Carrie
name: Leone, Austin
name: Gibson, J.
name: Naegle, Erin
Publisher: name: QUBES Educational Resources
Year: 2021

description: A short, multiple choice diagnostic designed to provide instructors with a quick check on students’ understanding of and ability to read and interpret phylogenies.
Additional file 5 of CLK1/SRSF5 pathway induces aberrant exon skipping of METTL14 and Cyclin L2 and promotes growth and metastasis of pancreatic cancer
Creators: name: Chen, Shi
name: Yang, Can
name: Wang, Zu-Wei
name: Hu, Jian-Fei
name: Pan, Jing-Jing
name: Liao, Cheng-Yu
name: Zhang, Jia-Qiang
name: Chen, Jiang-Zhi
name: Huang, Yi
name: Huang, Long
name: Zhan, Qian
name: Tian, Yi-Feng
name: Shen, Bai-Yong
name: Wang, Yao-Dong
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 5: Figure S4II. Interaction between CLK1 and SRSF5 in PANC-1 cells, BxPC-3 cells, and 293T cells. (A-E) HA-tagged CLK1 and Flag-tagged SRSF5 were transfected into PANC-1 cells (A), or BxPC-3 cells (B-C), or 293T cells (D-3). Co-immunoprecipitation and western blot assays were performed with the indicated antibodies.
Figure S5 from Aggression and discrimination among closely versus distantly related species of Drosophila
Creators: name: Gupta, Tarun
name: Howe, Sarah E.
name: Zorman, Marlo L.
name: Lockwood, Brent L.
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: Body length and body length difference had no effect on levels of aggression or aggression bias. (A) Body length did not differ between opponent species (Sidak’s multiple comparisons test, d.f. = 304; D. melanogaster vs. D. simulans, t = 1.98, P = 0.26; D. pseudoobscura vs. D. persimilis, t = 1.663, P = 0.46; D. pallidosa vs. D. ananassae, t = 0.2431, P = 0.99; D. simulans vs. D. ananassae, t = 1.566, P = 0.53; D. ananassae vs. D. atripex, t = 1.585, P = 0.52), except that D. melanogaster was slightly larger than D. ananassae (mean difference in body length: 0.09 cm; Sidak's multiple comparisons test, t = 3.572, P = 0.0025). However, size did not have an effect on aggression, as (B) there was no significant relationship between body length and total number of lunges from focal males in a given fight (Spearman p = -0.015, P = 0.85) and (C) there was no significant relationship between the difference in body lengths between males of opponent species and the number of heterospecific lunges in a given fight (Spearman p = -0.14, P = 0.24).
Drosophila spectabilis Hardy 1965
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila spectabilis

description: Drosophila spectabilis Hardy, 1965
Distribution: Endemic: Maui, Molokai
Additional References: Carson & Kaneshiro (1976); Carson & Stalker (1968c); Hardy (1966); Kambysellis (1993); Spieth (1984)
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 21, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841