cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Rallus Linnaeus 1758
Creators: name: Takano, Oona M.
name: Steadman, David W.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Gruiformes
Rallidae
Rallus

description: Genus Rallus Linnaeus, 1758
We refer the specimens of the new species to the genus Rallus (rather than Pardirallus, Porzana, Gallinula, Porphyrio, or Fulica) based on characters presented in Steadman et al. (2013), Zelenkov et al. (2017), and the following characters. Humerus: margo caudalis more distinct; more rounded proximo-caudal surface of shaft; in caudal aspect, less prominent tuberculum supracondylare ventrale (except in Porphyrio and Fulica.) Ulna: shaft relatively narrower, especially in ventral aspect (except in Pardirallus); depression between trochlea humeralis ulnaris and tuberculum ligamentum collateralis ventralis deeper. Femur: no consistent generic-level characters noted; referral based on size. Tibiotarsus: in cranial aspect, crista cnemialis lateralis much wider than long, with less bulbous cranial surface (except in Porzan a); cranio-medial and cranio-lateral margins of shaft more rounded; sulcus muscularis fibularis deeper. Tarsometatarsus (not available in Pardirallus): less concave proximo-acrotarsial surface of shaft; more rounded acrotarsial-medial and acrotarsial-lateral margins of shaft, especially in distal portion; more bulbous (convex) surface of acrotarsial-distal part of shaft supporting trochlea metatarsi III.
description: Published as part of Takano, Oona M. & Steadman, David W., 2018, Another new species of flightless Rail (Aves: Rallidae: Rallus) from Abaco, The Bahamas, pp. 376-382 in Zootaxa 4407 (3) on page 377, DOI: 10.11646/zootaxa.4407.3.5, http://zenodo.org/record/1216608
Ephippion guttifer
Creators: name: Carneiro, Miguel
name: Martins, Rogélia
name: Landi, Monica
name: Costa, Filipe O.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Tetraodontiformes
Tetraodontidae
Ephippion
Ephippion guttifer

description: Ephippion guttifer (Bennett, 1831)
– Prickly puffer; ①③
description: Published as part of Carneiro, Miguel, Martins, Rogélia, Landi, Monica & Costa, Filipe O., 2014, Updated checklist of marine fishes (Chordata: Craniata) from Portugal and the proposed extension of the Portuguese continental shelf, pp. 1-73 in European Journal of Taxonomy 73 on page 62, DOI: 10.5852/ejt.2014.73, http://zenodo.org/record/3866515
Lagocephalus laevigatus
Creators: name: Carneiro, Miguel
name: Martins, Rogélia
name: Landi, Monica
name: Costa, Filipe O.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Tetraodontiformes
Tetraodontidae
Lagocephalus
Lagocephalus laevigatus

description: □ Lagocephalus laevigatus (Linnaeus, 1758)
– Smooth puffer; Baiacu-verde ①, ③
description: Published as part of Carneiro, Miguel, Martins, Rogélia, Landi, Monica & Costa, Filipe O., 2014, Updated checklist of marine fishes (Chordata: Craniata) from Portugal and the proposed extension of the Portuguese continental shelf, pp. 1-73 in European Journal of Taxonomy 73 on page 62, DOI: 10.5852/ejt.2014.73, http://zenodo.org/record/3866515
Bozorgnites Cozar, Vachard, and Le Coze
Creators: name: Vachard, Daniel
name: Coze, François Le
name: Cózar, Pedro
name: Gaillot, Jérémie
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Chromista
Foraminifera
Fusulinata
Endothyrida
Eoparastaffellidae
Bozorgnites

description: Genus BOZORGNITES Cózar, Vachard, and Le Coze pro Bozorgniella Cózar and Vachard, 2001 emend.
zoobank.org/ 2A1D3B89-EEEA-493D-9605-D226E442AC74
Etymology. As Bozorgniella, Bozorgnites is named in honor of Dr. Fathollah Bozorgnia, who described the type species. The genus is masculine.
Type Species. Dainella tumultuosa Bozorgnia, 1973 (Figure 1). The holotype (Figure 1.3) is deposited in the collections of the Geological Laboratories of the National Iranian Oil Company, Tehran, Iran.
Diagnosis. Test free, asymmetrical, with the last volution semi-evolute to evolute. Permanent deviations of the axis of coiling, varying up to 45° in the internal volutions, and reaching 90° for the last volution. Strong chomata. Wall coarsely granular and relatively brownish. Rounded periphery in the last whorl, subcarinate periphery in the inner whorls.
Comparisons. Bozorgnites nom. nov. differs from Eoparastaffellina by the subcarinate inner whorls and from Eoparastaffella by the rounded periphery of the last whorl (Vachard and Arefifard, 2015).
Other species. Monotypic.
Occurrence. Endemic to Alborz (Iran), where it seems to be latest Tournaisian and/or early Visean in age.
Remarks. The genus Bozorgniella / Bozorgnites was introduced as a transitional form between the Dainellidae and the Eoparastaffellinae, but this hypothesis was refuted by Devuyst (2006), because, in Iran, Bozorgnites appears after the first Eoparastaffellina. As a result, Bozorgnites is most probably transitional between Eoparastaffellina (with an ancestral rounded periphery) and true (i.e., carinate) Eoparastaffella. On the other hand, due to its strong deviations of the axis, coarse wall, and very sharp chomata, Bozorgnites is also possibly transitional to Pojarkovella and its plexus, which are relatively common in Iran (Zandkarimi et al., 2014) and South China (Hance et al., 2011).
description: Published as part of Vachard, Daniel, Coze, François Le, Cózar, Pedro & Gaillot, Jérémie, 2019, Bozorgnites nom. nov. and Crassispirellina nom. nov.: New names for the preoccupied foraminiferal genera Bozorgniella and Crassispirella, pp. 1-7 in Palaeontologia Electronica (4 A) (4 A) 22 (1) on page 3, DOI: 10.26879/927, http://zenodo.org/record/11063018
Bulimulus Leach 1814
Creators: name: Breure, Abraham S. H.
name: Borrero, Francisco J.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Stylommatophora
Bulimulidae
Bulimulus

description: Genus Bulimulus Leach, 1814
Type species: Helix exilis Gmelin, 1791. Distribution: West Indies, Venezuela, Guyana, Surinam, French Guiana, Brazil, Paraguay, Uruguay, Argentina, Bolivia, Peru, Ecuador, Colombia, Panama, Costa Rica, Nicaragua, Guatemala, Belize, Mexico.
33. Bulimulus fontainii (d’Orbigny, 1837)
Type locality: Near Guayaquil. Holotype BMNH 1854.12.4.165.
Distribution: Guayas, near Guayaquil (FMNH 31339).
Remarks: This is the only species of Bulimulus s.str. and is well outside the range of this genus. Once revised this taxon may prove to be a synonym, possibly of Drymaeus cactivorus (Broderip).
description: Published as part of Breure, Abraham S. H. & Borrero, Francisco J., 2008, An annotated checklist of the land snail family Orthalicidae (Gastropoda: Pulmonata: Orthalicoidea) in Ecuador, with notes on the distribution of the mainland species, pp. 1-40 in Zootaxa 1768 on pages 9-10, DOI: 10.5281/zenodo.274265
Virtual screening of targeted acrylamide warheads for identification of covalent inhibitors of Cryptopain, a cysteine protease of Cryptosporidium parvum
Creators: name: Asmare, Misgana Mengistu
name: Dhal, Ajit Kumar
name: Mahapatra, Rajani Kanta
name: Yun, Soon-IL
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Cryptosporidiosis is an infection induced by the single-celled protozoan Cryptosporidium parasite. This parasite commonly infects the intestines of humans and animals, leading to gastrointestinal symptoms such as diarrhea, stomach cramps, nausea, and vomiting. Cryptopain protein, a type of cysteine protease found in the genome of Cryptosporidium parvum plays an important role in cell invasion and its survival. In this study, we mainly focused on the structural validation and reliability of docking aspects of the Cryptopain protein of C. parvum. The best-modeled structure of Cryptopain protein was run in a water environment through a 200 ns Molecular Dynamics (MD) simulation study. We employed a covalent docking scheme to screen suitable inhibitors against our target protein. Furthermore, the reliability of the binding mode for the best possible inhibitors was validated at a 100 ns time frame through a complex MD simulation study. From docking and simulation studies, we found Z3952175270 as a possible inhibitor on the basis of docking score and binding affinity for the possible binding site in the Cryptopain protein. Our findings highlight the potential of targeting Cryptopain protein with specific inhibitors, which could pave the way for the development of novel therapeutic strategies against cryptosporidiosis. This work contributes to the field by providing a deeper understanding of the molecular interactions involved in Cryptopain inhibition, potentially leading to effective treatments for a disease that significantly impacts public health, particularly in immunocompromised individuals and in areas with limited access to clean water.
La centralità dell’immaginario artistico nel costruire e decostruire l’immaginario territoriale. Le aree interne come campo di sperimentazione creativa e immaginazione collettiva
Creators: name: Crobe, Stefania
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: L’articolo esplora in che modo l’arte, intesa come pratica, possa rappresentare un approccio metodologico di interesse nell’ambito della ricerca urbana, per un’espansione del campo disciplinare e una riconfigurazione dell’urbano. Nell’attitudine all’attraversamento dei margini disciplinari, si riconosce nella pratica artistica uno strumento epistemologico decolonizzante le strutture razionali cartesiane e una prassi trasformativa abilitante. A partire da queste premesse, si farà riferimento al ruolo agito da pratiche e progettualità culturali in altri ‘margini’ – i centri minori in via di spopolamento e abbandono, i territori interni – per capire come la prassi dell’arte agisce per decostruire e ricostruire nuovi o altri immaginari territoriali.
description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 11 N. 15 (2024): Riconfigurazioni dell'urbano. Pratiche inedite di un abitare territoriale
L’esperienza dei Fumi della fornace a Valle Cascia. Una festa per re-immaginare una comunità
Creators: name: Compagnucci, Valentina
name: Michelini, Elisa
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: Il collettivo Congerie nasce in seno alle problematiche politiche e ambientali di Valle Cascia, frazione di Montecassiano, nella regione Marche. L’esperienza del gruppo rappresenta un caso emblematico di come le pratiche artistiche e performative possano fornire una lente di interpretazione, conoscenza e risemantizzazione del paesaggio e della comunità. La ricerca si focalizza sull’attività portata avanti dal collettivo nella frazione industriale di Valle Cascia, sorta agli inizi del Novecento, in concomitanza con l’apertura della Fornace Smorlesi, destinata alla produzione di laterizi che ha chiuso la sua attività produttiva nel 2012, lasciando un relitto architettonico, con estese coperture di amianto in stato di abbandono. La chiusura della fornace ha portato con sé lo sgretolamento della comunità operaia e la dissoluzione dell’identità dell’intero luogo. Dal 2019 il collettivo cura il progetto “I Fumi della fornace”, una festa che, a partire dall’idea del fallimento industriale, torna ad abitare lo spazio pubblico attraverso il momento collettivo e rituale. I dispositivi curatoriali proposti nella programmazione culturale offerta mettono in dialogo le testimonianze orali, la storia e le tradizioni del luogo con le soggettività attive nel campo delle arti visive e performative contemporanee.
description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 11 N. 15 (2024): Riconfigurazioni dell'urbano. Pratiche inedite di un abitare territoriale
Lagocephalus lagocephalus subsp. lagocephalus lagocephalus lagocephalus (Linnaeus 1758
Creators: name: Carneiro, Miguel
name: Martins, Rogélia
name: Landi, Monica
name: Costa, Filipe O.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Tetraodontiformes
Tetraodontidae
Lagocephalus
Lagocephalus lagocephalus
Lagocephalus lagocephalus lagocephalus (linnaeus, 1758)

description: * □ Lagocephalus lagocephalus lagocephalus (Linnaeus, 1758)
– Oceanic puffer; ①, Peixe-balão ②, Sapo③
description: Published as part of Carneiro, Miguel, Martins, Rogélia, Landi, Monica & Costa, Filipe O., 2014, Updated checklist of marine fishes (Chordata: Craniata) from Portugal and the proposed extension of the Portuguese continental shelf, pp. 1-73 in European Journal of Taxonomy 73 on page 62, DOI: 10.5852/ejt.2014.73, http://zenodo.org/record/3866515
Haemolaelaps Berlese
Creators: name: Shaw, Matthew D.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Laelapidae
Haemolaelaps

description: Genus Haemolaelaps Berlese
(Figs 1–9)
Laelaps (Haemolaelaps) Berlese, 1910: 261.
Laelaps (Haemolaelaps). — Berlese 1911: 432; 1922: 94. Hypoaspis (Haemolaelaps).— Berlese, 1916: 170; 1918: 123.
Type species Laelaps (Haemolaelaps) marsupialis Berlese 1910: 261; by monotypy and original designation.
Diagnosis. Female. Dorsum. Medium-sized to large mesostigmatan mites, length 610–920. Opisthonotum without unpaired accessory Jx setae. Paired accessory setae sometimes present within dorsal hexagon of podonotum (H. cleptusa). Seta J2 situated posterolateral to J1. Dorsal setae barbed except in H. quartus. Seta Z5 very long (260–330) in H. cleptusa.
Gnathosoma. Pilus dentilis flagelliform, not inflated (Fig. 3), 25–40 long (approximately as long as movable digit), except somewhat shorter in H. hattenae (ca. 14). Pilus dentilis inserted at or close to apex of digit. Corniculi converge strongly inwards (Fig. 6), weakly in H. cleptusa. Deutosternal groove with five (H. domrowi, H. marsupialis) or six transverse rows of denticles. Epistome a rounded lobe, with few to many denticles (Fig. 5).
Venter. (Fig. 4) Lateral edges of tritosternal base barbed (Fig. 7). Tritosternal lacinae free almost to suture (Fig. 7). Presternal striae with fringes except in H. quartus and H, hattenae. Sternal shield often with elongate setae. Median pore-like structure on post-stigmatal plate enlarged (> 4µm, Fig. 8), obviously much larger than anterior and posterior pore-like structures. Primary metapodal platelet narrow oval, not subcircular. Setae on unsclerotised opisthogaster barbed. Genito-ventral shield with 6–8 transverse striae (Fig. 9), or only five on the abbreviated shield of H. quartus. Genito-ventral shield bears st5, also sometimes Zv1, and more rarely Jv 1 in some individuals of H. cleptusa and H. hattenae. Genito-ventral shield falls short of anal shield. Post-anal seta frequently long and/or barbed.
Legs. Leg setation holotrichous as defined by Evans (1963). Genu IV with a single proximally positioned pl seta (pl2). Some leg setae always barbed: trochanter I d; femur I ad1, pd1, pd2; femur II ad1, pd1, pd2; femur III ad1; femur IV ad1, ad2. The femur, genu and tibia of leg II bear thickened ventral setae in H. domrowi.
Male. Males are known for H. cleptusa, H. domrowi, H. marsupialis and H. flagellatus. Fixed digit of male distinctly reduced in known males, though only slightly so in H. marsupialis. Flagelliform pilus dentilis inserted at apex of fixed digit. Spermadactyl bent abruptly upwards. Spermadactyl tip flared in H. cleptusa. Holoventral shield bearing st1–5, circum-anal setae and five other pairs of setae.
description: Published as part of Shaw, Matthew D., 2014, Haemolaelaps Berlese removed from synonomy with Androlaelaps Berlese (Acari: Laelapidae), pp. 285-292 in Zootaxa 3841 (2) on pages 287-289, DOI: 10.11646/zootaxa.3841.2.7, http://zenodo.org/record/230261
La Città Autistica. Alberto Vanolo, Einaudi (2024)
Creators: name: Piras, Gioacchino
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 11 N. 15 (2024): Riconfigurazioni dell'urbano. Pratiche inedite di un abitare territoriale
Scutalus Albers 1850
Creators: name: Breure, Abraham S. H.
name: Borrero, Francisco J.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Stylommatophora
Orthalicidae
Scutalus

description: Genus Scutalus Albers, 1850
Remarks: Breure (1979) placed Thaumastus umbilicatus Miller, 1879 (type locality: Prov. Loja, Catamayo, 2000–3000 ft.) under Nomina inquirenda, doubtfully suggesting that it might be a Scutalus.
Subgenus Scutalus (Vermiculatus) Breure, 1978
Type species: Bulimus bicolor Sowerby, 1835. Distribution: Bolivia, Peru, Ecuador.
99. Scutalus (Vermiculatus) aequatorius (Pfeiffer, 1853)
Type locality: Mountain Schinchulagua. Lectotype BMNH 1975377 (Breure 1979).
Distribution: Chimborazo, Cerro Chanchalahua, a foothill of Cerro Chimborazo (BMNH 1975178/1 paralectotype); “Chimborazo” (ZMZ 512209); Cotopaxi, Cerro Cotopaxi (ZMB); Napo, Antisana (FMNH 124573; MCZ 193333; ZMB); Pastaza, Cerros de Abitagua (FMNH 129020); “Quito” (CMC C11763, ZMH 7625).
100. Scutalus (Vermiculatus) anthisanensis (Pfeiffer, 1853)
Type locality: Mountain Anthisana. Lectotype BMNH 1975372. Bulimus cotopaxensis Pfeiffer, 1853 (type locality: Mountain Cotopaxi, lectotype BMNH 1975370) and Bulimus subfasciatus Pfeiffer, 1853 (type locality: Anthisana, lectotype BMNH 1975368) are considered synonyms, following Weyrauch 1967: 385 [see Breure 1978: 185].
Distribution: Chimborazo, Cerro Altar (ZMB); Cotopaxi, Cerro Cotopaxi (BMNH 1975371/1 paralectotype); Sigchos (RMNH); Napo, Cerro Antisana (BMNH 1975373/1 paralectotype of Bulimus anthisanensis Pfeiffer; BMNH 1975369/1 paralectype of Bulimus subfasciatus Pfeiffer; ZMB); Pichincha, Cayambe (BMNH); San Francisco (HMNH)*. “Quito” (CMC C11762; ZMZ 512211, as B. subfasciatus Pfeiffer). “ Ecuador ” (ZMZ 512218, 512219; ZMZ 512213, as B. subfasciatus Pfeiffer; ZMZ 512228, as B. cotopaxiensis Pfeiffer).
Remarks: As Cerro Cotopaxi forms the cross of intersection of the provinces of Cotopaxi, Pichincha and Napo, we have arbitrarily attributed the locality to Cotopaxi, not knowing on which slope the type material was taken.
101. Scutalus (Vermiculatus) cousini (Jousseaume, 1887) Type locality: “Concha”. Holotype MNHN.
Distribution:? Morona-Santiago, Conchay (MNHN). Remarks: Conchay is the only name that turns up in the GNS, that is closely resembling the original locality.
Scutalus sp.
Distribution: Azuay, Paute (FLMNH 151259); Pichincha, near Pucará (HMNH).
description: Published as part of Breure, Abraham S. H. & Borrero, Francisco J., 2008, An annotated checklist of the land snail family Orthalicidae (Gastropoda: Pulmonata: Orthalicoidea) in Ecuador, with notes on the distribution of the mainland species, pp. 1-40 in Zootaxa 1768 on page 18, DOI: 10.5281/zenodo.274265
Lo straniero abitante. Margine e centro nel paradigma della mobilità
Creators: name: Marzo, Alberto
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: A partire da una ricognizione su quella letteratura che individua nel paradigma della mobilità una delle principali chiavi interpretative della contemporaneità, il saggio propone una riflessione più ampia su come forme temporanee dell’abitare, più o meno inedite, sembrino indicare un superamento della più classica dicotomia urbano /rurale. In un contesto come quello delle cosiddette aree marginali, interne, sempre più al centro di attraversamenti e usi stagionali e controversi quali il turismo o il fenomeno delle seconde case, trovano spazio nuove forme di attaccamento ai luoghi, sperimentazioni di multiappartenenza che suggeriscono un ampliamento del concetto stesso di casa.
description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 11 N. 15 (2024): Riconfigurazioni dell'urbano. Pratiche inedite di un abitare territoriale
Sphoeroides marmoratus
Creators: name: Carneiro, Miguel
name: Martins, Rogélia
name: Landi, Monica
name: Costa, Filipe O.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Tetraodontiformes
Tetraodontidae
Sphoeroides
Sphoeroides marmoratus

description: □ Sphoeroides marmoratus (Lowe, 1838)
– Guinean puffer; ①, Peixe-balão, Sopapo or Sapo ②, Sapinho ③
The records for Sphoeroides spengleri (Bloch, 1785) should be replaced by S. marmoratus in the eastern Atlantic (P. Wirtz, pers. comm. Oct. 2004, in FishBase, Froese & Pauly 2012).
description: Published as part of Carneiro, Miguel, Martins, Rogélia, Landi, Monica & Costa, Filipe O., 2014, Updated checklist of marine fishes (Chordata: Craniata) from Portugal and the proposed extension of the Portuguese continental shelf, pp. 1-73 in European Journal of Taxonomy 73 on page 63, DOI: 10.5852/ejt.2014.73, http://zenodo.org/record/3866515
Riconfigurazioni dell'urbano. Pratiche inedite di un abitare territoriale
Creators: name: Decandia, Lidia
name: Attili, Giovanni
name: Agati, Natalia
name: Marzo, Alberto
name: Olcuire, Serena
name: Satta, Caterina
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 11 N. 15 (2024): Riconfigurazioni dell'urbano. Pratiche inedite di un abitare territoriale
Le nuove dimensioni dell’urbano e la riscoperta del territorio: una nuova sfida per il progetto. Una conversazione con Giovanni Maciocco
Creators: name: Decandia, Lidia
name: Maciocco, Giovanni
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 11 N. 15 (2024): Riconfigurazioni dell'urbano. Pratiche inedite di un abitare territoriale
Dilophotes kubani
Creators: name: Bic, Vlastislav
Publisher: name: Zenodo
Year: 2002
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Lycidae
Dilophotes
Dilophotes kubani

description: Dilophotes kubani group
Diagnosis. The male genitalia are very characteristic (Fig. 25). Their shape does not show close relationship of D. kubani sp. n. to any known Dilophotes, and therefore it is classified as a separate species group.
description: Published as part of Bic, Vlastislav, 2002, Review of the genus Dilophotes Waterhouse (Coleoptera: Lycidae) of the Palaearctic Region and Indochina, pp. 1-26 in Zootaxa 59 on page 21, DOI: 10.5281/zenodo.155977
Tra policy e agency. Uno sguardo etnografico su Bastogi come ‘spazio intermedio’ urbano
Creators: name: Marasco, Mario
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: Questo contributo mette al centro il ruolo del ricercatore sociale presso Bastogi, un centro di assistenza alloggiativa temporanea (CAAT) a Roma, mostrando come i processi di soggettivazione in condizione di forte marginalità, da un lato, e le retoriche e le pratiche del decisore politico, dall’altro, creino una tensione meritevole di essere indagata con la lente concettuale dello ‘spazio intermedio’. Lo studio procede da una ricerca etnografica di lunga durata che si è andata aggiungendo ad una più recente esperienza di antropologia applicata. Quest’ultima postura viene parimenti messa in discussione a favore di un uso sociale della ricerca, la quale non esula l’antropologo dal prendere una posizione (etica) senza sostituirsi alle voci degli attori sociali coinvolti nello studio. Il concetto di ‘spazio intermedio’ viene ripreso da più angolazioni, non solo partendo dai dati etnografici ma anche come spunto per riflessioni di ordine epistemologico.
description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 12 N. 16 (2024): Chi apprende da chi? Sguardi interdisciplinari tra azione pubblica e pratiche dal basso
Земляника садовая на Среднем Урале
Creators: name: Павлова О.А.
name: Сорокопудов В.Н.
Publisher: name: Zenodo
Year: 2024

description: Состояние производства земляники в России, в частности на Среднем Урале. Сорта селекции Свердловской ССС и других НИУ в условиях Среднего Урала
Ordralfabetix Szwedo, 2011, gen. n.
Creators: name: Szwedo, Jacek
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Lophopidae
Ordralfabetix

description: Genus Ordralfabetix gen. n.
Type species. Ordralfabetix sirophatanis sp. n., here designated.
Diagnosis. Regarding the pattern of tegmen venation, the forking of the main stems resembles that of genera placed in the Sarebasa + group defined by Soulier-Perkins (2000, 2001) and Soulier-Perkins et al. (2007). Tegmen with long and narrow costal area developed, intersected by scarce transverse veinlets; clavus narrowly open, with a few transverse veinlets between CuP and Pcu and CuP and Pcu+A1; Hind wing with quite long, oblique veinlet r-m, oblique veinlet m-cua at the same level and a few veinlets icua at same level; stem M forked slightly basad of veinlet r-m and apicad of veinlet m-cua, branch M1+2 forked in apical portion of wing; stem CuA forked basad of half of hind wing length, branch CuA1 forked distinctly basad of stem ScR forking.
Description. Head with vertex wider at base than long in midline. Pronotum in midline shorter than vertex in midline. Mesonotum with three carinae, lateral carinae strongly converging anteriad, curved and connected with median carina, lateral carinae reaching posterior margin of mesonotum. Tegmen about 3.5 times as long as wide, with apical portion oblongly elongate; membrane long, tip of clavus not reaching half of tegmen length; costal area about ⅔ as wide as costal cell, with apex distinctly exceeding level of apex of clavus, intersected by transverse veinlets; branch ScRA1 strongly oblique, reaching Pc+CP before its apex, slightly apicad of level of claval apex; costal cell without transverse veinlets; stem ScR with supernumerary terminals; stem M3+4 forked basad of stem M1+2 forking; stem CuA forked slightly apicad of stem M forking; postcubital cell with a few transverse veinlets; claval veins Pcu and A1 coalesced slightly apicad of half of clavus length, apicad of stem CuA forking.
Etymology. Genus named after a character from the “Asterix the Gaul ” comic books series. Gender: masculine, Ordralfabetix, ~cis, 3rd declension.
Composition. Only the type species is known.
description: Published as part of Szwedo, Jacek, 2011, Ordralfabetix sirophatanis gen. et sp. n. — the first Lophopidae from the Lowermost Eocene Oise amber, Paris Basin, France (Hemiptera: Fulgoromorpha), pp. 52-60 in Zootaxa 2822 on page 53, DOI: 10.5281/zenodo.207772
Stenostylus Pilsbry 1898
Creators: name: Breure, Abraham S. H.
name: Borrero, Francisco J.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Stylommatophora
Orthalicidae
Stenostylus

description: Genus Stenostylus Pilsbry, 1898
Type species: Bulimus nigrolimbatus Pfeiffer, 1854. Distribution: Venezuela, Peru, Ecuador, Colombia. 102. Stenostylus colmeiroi (Hidalgo, 1872)
Type locality: Baeza. Holotype MNHN (refigured by Breure 1976).
Distribution: Napo, Baeza.
Remarks: Material in the Florida museum has been found under the name of Simpulopsis colmeiroi. However, compared to the figure of the type, these specimens lack the whitish axial streaks on the last whorls and have the aperture slightly more elongate. They proved to be S. citrinovitrea (Moricand). See also Breure (2008).
description: Published as part of Breure, Abraham S. H. & Borrero, Francisco J., 2008, An annotated checklist of the land snail family Orthalicidae (Gastropoda: Pulmonata: Orthalicoidea) in Ecuador, with notes on the distribution of the mainland species, pp. 1-40 in Zootaxa 1768 on page 19, DOI: 10.5281/zenodo.274265
Spanish Translation: Plain language summary of the updated results from the CROWN study comparing lorlatinib with crizotinib in people with advanced non-small-cell lung cancer
Creators: name: Solomon, Benjamin J.
name: Bauer, Todd M.
name: Liu, Geoffrey
name: Mazieres, Julien
name: de Marinis, Filippo
name: Goto, Yasushi
name: Kim, Dong-Wan
name: Wu, Yi-long
name: Jassem, Jacek
name: López, Froylán López
name: Soo, Ross A.
name: Shaw, Alice T.
name: Polli, Anna
name: Messina, Rossella
name: Iadeluca, Laura
name: Toffalorio, Francesca
name: Felip, Enriqueta
Publisher: name: Taylor & Francis
Year: 2024

description: What is this summary about?: This summary shows the updated results of an ongoing research study called CROWN that was published in The Lancet Respiratory Medicine in December 2022. In the CROWN study, researchers looked at the effects of two study medicines called lorlatinib and crizotinib. The study included people with advanced non-small-cell lung cancer (NSCLC) that had not been treated previously. All people in the study had cancer cells with changes (known as alterations) in a gene called anaplastic lymphoma kinase, or ALK. This ALK gene is involved in cancer growth. In this updated study, researchers looked at the continued benefit in people who took lorlatinib compared with people who took crizotinib after 3 years.What did this study find?: After 3 years of being observed, people who took lorlatinib were more likely to be alive without their cancer getting worse than people who took crizotinib. At 3 years, 64% of people who took lorlatinib were alive without their cancer getting worse compared with 19% of people who took crizotinib. The cancer was less likely to have spread within or to the brain in people who took lorlatinib than in people who took crizotinib. After 3 years of being observed, 61% of people were still taking lorlatinib and 8% of people were still taking crizotinib. People who took lorlatinib had more severe side effects than people who took crizotinib. However, these side effects were manageable. The most common side effects with lorlatinib were high levels of cholesterol or high levels of triglycerides (a type of fat) in the blood. Life-threatening side effects were seen in 13% of people who took lorlatinib and 8% in crizotinib. Two people who took lorlatinib died because of side effects from lorlatinib.What do the results of the study mean?: The updated results from the CROWN study showed that a larger percentage of people who took lorlatinib continued to benefit from their treatment after being observed for 3 years compared with those who took crizotinib.
"Ci dite questi ragazzi chi sono?" Percorsi di giustizia minorile tra pena e sostegno
Creators: name: Ricciardi, Fabio
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: Questo contributo, tramite la descrizione di un frammento etnografico, cerca di indagare quegli interstizi che vedono protagonisti lo Stato attraverso l’agire dei suoi incaricati e gli operatori sociali che si trovano a contatto con la giustizia penale minorile. Attraverso la descrizione di una situazione specifica che vede come protagonisti un’assistente sociale, una mediatrice, operatori sociali e un minorenne raggiunto da un provvedimento dell’autorità giudiziaria, si cercherà di rendere conto delle differenti dimensioni, strategie e posizionamenti che caratterizzano l’interazione tra istituzioni pubbliche e privato sociale attraverso la quotidianità lavorativa degli attori che vi sono immersi.
description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 12 N. 16 (2024): Chi apprende da chi? Sguardi interdisciplinari tra azione pubblica e pratiche dal basso
Sphoeroides pachygaster
Creators: name: Carneiro, Miguel
name: Martins, Rogélia
name: Landi, Monica
name: Costa, Filipe O.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Tetraodontiformes
Tetraodontidae
Sphoeroides
Sphoeroides pachygaster

description: * Sphoeroides pachygaster (Müller & Troschel, 1848)
– Blunthead puffer; Peixe-bola ①, Peixe-balão or Sapo-do-alto ②, ③
description: Published as part of Carneiro, Miguel, Martins, Rogélia, Landi, Monica & Costa, Filipe O., 2014, Updated checklist of marine fishes (Chordata: Craniata) from Portugal and the proposed extension of the Portuguese continental shelf, pp. 1-73 in European Journal of Taxonomy 73 on page 63, DOI: 10.5852/ejt.2014.73, http://zenodo.org/record/3866515
Rethinking the innovativeness of civic initiatives: institutionalised practices as resources for action and limits to innovation
Creators: name: Campagnari, Francesco
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: L’impegno di pubbliche amministrazioni ed iniziative civiche nella risoluzione di problemi pubblici è stato interpretato considerando l’azione delle prime come istituzionalizzate, rigide e incapaci di apprendere, e quella delle seconde come flessibile, sperimentale, innovativa. Recenti ricerche hanno tuttavia sottolineato come le iniziative civiche possano sviluppare processi di istituzionalizzazione. In linea con questa prospettiva, il presente contributo esplora come l’istituzionalizzazione influenzi l’impegno delle iniziative civiche in nuove situazioni problematiche. Analizzando casi di studio in Slovacchia e in Francia, si sostiene che le iniziative istituzionalizzate possono confrontarsi con queste situazioni aprendo nuovi processi sperimentali, in cui le loro pratiche istituzionalizzate possono essere risorse per l’azione; la loro capacità di sviluppare innovazione istituzionale sulla base di queste nuove esperienze è tuttavia limitata, suggerendo che l’innovatività delle iniziative civiche vada problematizzata.
description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 12 N. 16 (2024): Chi apprende da chi? Sguardi interdisciplinari tra azione pubblica e pratiche dal basso
Dilophotes lizipingensis Bic, 2002, sp. n.
Creators: name: Bic, Vlastislav
Publisher: name: Zenodo
Year: 2002
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Lycidae
Dilophotes
Dilophotes lizipingensis

description: Dilophotes lizipingensis sp. n.
Type material. Holotype, male, " China, Sichuan, Liziping, 28. 6.­3. 7. 1991" (LMBC). Paratypes: 1 male, 1 female, " China, W. Guizhou prov., Leigongshan, Xijiang, 29. 5.­2. 6. 1997, 1200­1900 m, Bolm leg." (LMBC).
Diagnosis. Dilophotes lizipingensis sp. n. has flabellate male antennae but it is similar in body colouration to the dark red species belong to the other species groups based on their structure of male genitalia. Within groups having flabellate antennae it is well defined by the shape of its phallus and internal sac (Fig. 23).
Description of holotype. Body medium sized, slender, black, pronotum black with brown margins, elytra dark brown to black, only humeri brownish red, both body part covered with dark red dense pubescence. Eyes small, interocular distance 1.38 times maximum eye diameter. Head with short rostrum. Antennae flabellate, lamella of antennomere 7 3.5 times trunk of antennomere (Fig. 4). Pronotum transverse, 1.5 times wider than long, frontal margin widely rounded, frontal angles inconspicuous, lateral margins very slightly concave, posterior angles slightly projected (Fig. 7). Disc with sharp longitudinal costa from frontal margin almost reaching posterior margin. Disc surface densely pubescent. Scutellum simply rounded. Elytra very slender, flat, each elytron with three longitudinal costae. Costa 1 and 2 weak, costa 3 strong especially in humeral quarter. Male genitalia with short phallus and partly sclerotized internal sac (Fig. 23).
Measurements. BL 6.5 mm, WH 1.65 mm, PL 0.93 mm, PW 1.43 mm, Ediam 0.40 mm, Edist 0.55 mm.
Distribution. Dilophotes lizipingensis sp. n. should be widely distributed species in China, but at present it is known only from two distant localities in western Sichuan and Guizhou.
Etymology. The specific epithet is derived from the local name Liziping in Sichuan, China.
description: Published as part of Bic, Vlastislav, 2002, Review of the genus Dilophotes Waterhouse (Coleoptera: Lycidae) of the Palaearctic Region and Indochina, pp. 1-26 in Zootaxa 59 on page 19, DOI: 10.5281/zenodo.155977
Dilophotes holzschuhi Bic, 2002, sp. n.
Creators: name: Bic, Vlastislav
Publisher: name: Zenodo
Year: 2002
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Lycidae
Dilophotes
Dilophotes holzschuhi

description: Dilophotes holzschuhi sp. n.
Type material. Holotype, male, "W­Bhutan, Thimphu Distr., E of Dochu­la, Menshunang, 2400 m, 7. 7. 1988, C. Holzschuh leg." (LMBC). Paratype: 1 male, "NE India, Menghalaya, 3 km E of Tura, 500­1150 m, 23.30°N, 90.14°E, 1.­ 8. 5. 1999, Dembický & Pacholátko leg." (LMBC).
Diagnosis. The internal sac is similar to that of D. qinlinganus, but the upper plate is smaller and straight dorsally (Fig. 13). Externally, D. holzschuhi sp. n. is reminiscent of the dark coloured species from southern China and Laos, which belong to different species groups.
Description of holotype. Body medium sized, slender, black, pronotum light reddish brown, elytra red, both covered with dense red pubescence. Head with short rostrum. Eyes small, interocular distance 1.45 times maximum eye diameter. Antennae very slightly serrate, subapical antennomeres almost parallel­sided. Maxillary palpi slender. Pronotum 1.27 times wider than long. Frontal margin widely rounded, frontal angles inconspicuous, lateral margins almost straight, posterior margin weakly convex in middle. Disc with sharp longitudinal costa anteriorly. Scutellum black. Elytra slender, flat, each elytron with three longitudinal costae. Costa 1 inconspicuous in apical half. Male genitalia slender, long, both lower and upper plates of internal sac small, dorsal margin of upper plate straight basally (Fig. 13).
Measurements. BL 1.54 mm, WH 1.48 mm, PL 0,99 mm, PW 1.26 mm, Ediam 0.36 mm, Edist 0.53 mm.
Distribution. Dilophotes holzschuhi sp. n. occurs in mountainous areas in Bhutan and in south eastern India at Bangladesh border.
Etymology. The specific epithet is a patronym in honour of Carolus Holzschuh (Vienna), a collector of the holotype.
description: Published as part of Bic, Vlastislav, 2002, Review of the genus Dilophotes Waterhouse (Coleoptera: Lycidae) of the Palaearctic Region and Indochina, pp. 1-26 in Zootaxa 59 on page 11, DOI: 10.5281/zenodo.155977
Japanese translation - Plain language summary of the updated results from the CROWN study comparing lorlatinib with crizotinib in people with advanced non-small-cell lung cancer
Creators: name: Solomon, Benjamin J.
name: Bauer, Todd M.
name: Mok, Tony S. K.
name: Liu, Geoffrey
name: Mazieres, Julien
name: De Marinis, Filippo
name: Goto, Yasushi
name: Kim, Dong-Wan
name: Wu, Yi-long
name: Jassem, Jacek
name: López, Froylán López
name: Soo, Ross A.
name: Shaw, Alice T.
name: Polli, Anna
name: Messina, Rossella
name: Iadeluca, Laura
name: Toffalorio, Francesca
name: Felip, Enriqueta
Publisher: name: Taylor & Francis
Year: 2024

description: What is this summary about?: This summary shows the updated results of an ongoing research study called CROWN that was published in The Lancet Respiratory Medicine in December 2022. In the CROWN study, researchers looked at the effects of two study medicines called lorlatinib and crizotinib. The study included people with advanced non-small-cell lung cancer (NSCLC) that had not been treated previously. All people in the study had cancer cells with changes (known as alterations) in a gene called anaplastic lymphoma kinase, or ALK. This ALK gene is involved in cancer growth. In this updated study, researchers looked at the continued benefit in people who took lorlatinib compared with people who took crizotinib after 3 years.What did this study find?: After 3 years of being observed, people who took lorlatinib were more likely to be alive without their cancer getting worse than people who took crizotinib. At 3 years, 64% of people who took lorlatinib were alive without their cancer getting worse compared with 19% of people who took crizotinib. The cancer was less likely to have spread within or to the brain in people who took lorlatinib than in people who took crizotinib. After 3 years of being observed, 61% of people were still taking lorlatinib and 8% of people were still taking crizotinib. People who took lorlatinib had more severe side effects than people who took crizotinib. However, these side effects were manageable. The most common side effects with lorlatinib were high levels of cholesterol or high levels of triglycerides (a type of fat) in the blood. Life-threatening side effects were seen in 13% of people who took lorlatinib and 8% in crizotinib. Two people who took lorlatinib died because of side effects from lorlatinib.What do the results of the study mean?: The updated results from the CROWN study showed that a larger percentage of people who took lorlatinib continued to benefit from their treatment after being observed for 3 years compared with those who took crizotinib.
Chilomycterus atringa
Creators: name: Carneiro, Miguel
name: Martins, Rogélia
name: Landi, Monica
name: Costa, Filipe O.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Tetraodontiformes
Diodontidae
Chilomycterus
Chilomycterus atringa

description: ◇□ Chilomycterus atringa (Linnaeus, 1758)
– Porcupine fish; Peixe-porco ①, ②, Sapo ③
description: Published as part of Carneiro, Miguel, Martins, Rogélia, Landi, Monica & Costa, Filipe O., 2014, Updated checklist of marine fishes (Chordata: Craniata) from Portugal and the proposed extension of the Portuguese continental shelf, pp. 1-73 in European Journal of Taxonomy 73 on page 63, DOI: 10.5852/ejt.2014.73, http://zenodo.org/record/3866515
Condizioni attuali e sviluppi possibili del regime urbano di Roma: dal laissez-faire alla governance collaborativa?
Creators: name: Simoncini, Stefano
name: Brignone, Luca
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: Nonostante le sue peculiarità, Roma costituisce un caso paradigmatico dei processi globali che localmente generano frammentazione territoriale e sociale, con una forte preminenza della rendita urbana. Il paper propone di superare una visione deterministica dei regimi urbani adottando l'Actor-Network Theory (ANT) di Bruno Latour, che considera la società come un campo dinamico di relazioni, comprendente attori umani e non umani. Questo approccio consente di rilevare l'ambivalenza del regime urbano di Roma, che ha favorito sia la rendita che l'autorganizzazione, generando un contesto territorialmente molto problematico ma socialmente caratterizzato da un elevato potenziale trasformativo. Come dimostra il caso studio presentato, come attore terzo, l’università, facendo leva su questo potenziale, può favorire un'apertura delle istituzioni a spazi di apprendimento mutuo volti a sperimentare forme di governance collaborativa improntata al commoning e a modelli di sviluppo locale alternativi.
description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 12 N. 16 (2024): Chi apprende da chi? Sguardi interdisciplinari tra azione pubblica e pratiche dal basso
A STUDY ON PROFITABILITY ANALYSIS OF ULTRATECH CEMENT LIMITED IN INDIA
Creators: name: Dr. K. Bhuvaneswari* & S. Dharshini**
Publisher: name: Zenodo
Year: 2025

description: The purpose of this study is to Profitability relationship between the dependent (Debt Equity Ratio) and independent variable (Current Ratio, Return on Asset, Asset Structure, Return on Equity, Interest Coverage Ratio) in the model of the Ultratech Cement Limited in India from the financial year 2015-2024 .Data are analysed using Correlation and Regression analysis to find the association between the variables. The results shows that Return on Equity have a significant impact on Debt Equity Ratio. The result also shows Current Ratio, Return on Asset, Asset Structure, Interest Coverage Ratio negatively associated with Debt Equity Ratio. These results are consisting with previous empirical studies. Further recommendations are presented in the research.
Simpulopsis Beck 1837
Creators: name: Breure, Abraham S. H.
name: Borrero, Francisco J.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Stylommatophora
Simpulopsidae
Simpulopsis

description: Genus Simpulopsis Beck, 1837
149. Simpulopsis (Eudioptus) citrinovitrea (Moricand, 1836)
Type locality: Brazil, Bahia, near Salvador. Syntypes MNHN.
Distribution: Napo, Baeza; 5.5 km SSE Baeza (FLMNH 37384)*; 19.3 km NNE Baeza (FLMNH 37385)*; Pichincha, 59 km by road W Machachi, 1250m (RMNH)*.
Remarks: The material from the Florida Museum was labelled as Simpulopsis colmeiroi (Hidalgoi). This appears to be a misidentification, comparing the material with other specimens of S. citrinovitrea at hand, both from Ecuador and from Brazil.
description: Published as part of Breure, Abraham S. H. & Borrero, Francisco J., 2008, An annotated checklist of the land snail family Orthalicidae (Gastropoda: Pulmonata: Orthalicoidea) in Ecuador, with notes on the distribution of the mainland species, pp. 1-40 in Zootaxa 1768 on page 25, DOI: 10.5281/zenodo.274265
Spanish Translation - Prostate-specific antigen decline with apalutamide therapy is associated with longer survival and improved outcomes in individuals with metastatic prostate cancer: a plain language summary of the TITAN study
Creators: name: Chowdhury, Simon
name: Bjartell, Anders
name: Agarwal, Neeraj
name: H Chung, Byung
name: J Pereira de Santana Gomes, Andrea
name: Merseburger, Axel S
name: Özgüroğlu, Mustafa
name: Soto, Álvaro Juárez
name: Uemura, Hirotsugu
name: Ye, Ding-Wei
name: Brookman-May, Sabine D.
name: Londhe, Anil
name: Chi, Kim N.
Publisher: name: Taylor & Francis
Year: 2024

description: What is this summary about?This summary describes the results from an additional (or post hoc) analysis of the TITAN study. The TITAN study looked at whether the prostate cancer treatment apalutamide could be used to treat individuals with metastatic castration-sensitive prostate cancer (or mCSPC). A total of 1052 participants with mCSPC were included in the TITAN study. Treatment with apalutamide was compared with treatment with placebo. All participants received androgen deprivation therapy (or ADT), which is a type of hormone therapy that has been part of the main treatment for mCSPC for many years. The results showed that apalutamide plus ADT increased the length of time that participants remained alive compared with placebo plus ADT. Apalutamide plus ADT also controlled the growth of the cancer for a longer length of time compared with placebo plus ADT. Additionally, participants who received apalutamide plus ADT experienced a greater reduction in the blood levels of prostate-specific antigen (or PSA), called a deep PSA decline, compared with those who received placebo plus ADT. An additional (or post hoc) analysis was carried out to understand whether a decrease in blood PSA levels, in response to treatment, was associated with improved outcomes, including longer survival time.
What were the results of the additional analysis?In participants who received apalutamide plus ADT, a deep PSA decline in response to treatment was associated with longer survival time and improved outcomes.
What do these results mean for individuals with mCSPC?These results demonstrate that individuals with mCSPC can benefit from treatment with apalutamide plus ADT. The association seen between deep PSA decline and the longer survival time and improved outcomes highlights how PSA measurements can be used to help monitor cancer disease evolution in response to treatment. Monitoring PSA levels will assist doctors and other healthcare professionals to understand how effectively a treatment is working for a patient and to tailor their treatment approach to improve PSA decline.