cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
EXPLORING THE STRUCTURAL DETERMINANTS OF EBOLAVIRUS MATRIX PROTEIN (VP40) DIMER INTERFACE: BIOPHYSICAL AND PEPTIDOMIMETIC ANALYSIS OF DIMER STABILITY
Creators: name: Saxena, Roopashi
Publisher: name: Purdue University Graduate School
Year: 2024
Subjects: classificationCode: 310112
subject: Structural biology (incl. macromolecular modelling)

description: Ebola virus is an enveloped filamentous shaped RNA virus which causes severe hemorrhagic fever in humans. Multiple outbreaks of different strains of ebolavirus have been reported in the past years with limited therapeutics available for treatment. Despite some advances in treatment, there remains a lack of knowledge about the mechanisms of ebolavirus replication in host cells.Ebolavirus encodes for seven structural proteins with matrix protein (VP40) being the most abundantly expressed viral protein. VP40 is essential for viral assembly and budding as expression of VP40 alone is sufficient for formation of virus-like particles (VLPs). VP40 also disassembles during viral entry to help in viral and host cell membrane fusion. Oligomerization of VP40 has been reported to decrease viral replication and transcription. VP40 can perform these diverse functions by virtue of changes in conformation and oligomerization state. VP40 predominantly exists as a dimer through hydrophobic interactions between the alpha helices of the two protomers. Furthermore, VP40 oligomerizes into a hexamer which serves as the structural unit for cylindrical matrix layer formation. VP40 also forms a ring-shaped octamer for regulation of viral transcription. The different oligomeric forms of VP40 exist in an equilibrium for successful viral infection. However, the exact mechanism of formation, stability, and energetics of conversion between these oligomeric forms is unknown.In this study, we performed biophysical analysis on the dimerization interface and identified keystone interactions which when abrogated lead to complete disruption of dimer interface. In addition, peptidomimetics approach was used to design and synthesize a library of compounds to probe the dimerization interface. The compounds were screened using thermal shift assay and then compared using MST and ITC studies. We identified that a peptide mimicking the alpha helical region stabilized by a p-xylene di-cysteine staple was able to bind to VP40 dimer. We also determined that this peptide binds near the dimer interface and was able to slightly shift equilibrium of VP40 dimer towards monomer formation.Overall, this report sheds light on critical interactions required for VP40 dimer formation and stability and introduces use of peptidomimetics to probe for VP40 dimerization interface to understand energetics of oligomerization equilibrium, thereby increasing our knowledge about disease mechanism and paving way for development of therapeutics.
Additional file 2 of Changes in dementia diagnoses in Sweden during the COVID-19 pandemic
Creators: name: Axenhus, Michael
name: Schedin-Weiss, Sophia
name: Tjernberg, Lars
name: Wimo, Anders
name: Eriksdotter, Maria
name: Bucht, Gustaf
name: Winblad, Bengt
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2: Supplementary Table 1. Dementia diagnoses per age and sex group during 2015–2020. A decline in dementia diagnoses can be detected in most groups even before the COVID-19 pandemic.
Laporan Praktikum 2 BTT- Anak Kelas Magnoliidae (Nida Zahra Al Banna/180101110569)
Creators: name: Banna, Nida Zahra Al
Publisher: name: Zenodo
Year: 2020

description: Ini Laporan 2 Anak Kelas Magnoliidae Botani Tumbuhan Tinggi Oleh: Nida Zahra Al Banna (180101110569)
Agronomic management response in maize (Zea mays L.) production across three agroecological zones of Kenya
Creators: name: Kipkulei, Harison Kiplagat
name: Sonoko Bellingrath-Kimura, Dorothea
name: Lana, Marcos
name: Ghazaryan, Gohar
name: Baatz, Roland
name: Matavel, Custodio Efraim
name: Boitt, Mark
name: Chisanga, Charles Bwalya
name: Rotich, Brian
name: Moreira, Rodrigo Martins
name: Sieber, Stefan
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: 630 Landwirtschaft und verwandte Bereiche

description: Maize (Zea mays L.) productivity in Kenya has witnessed a decline attributed to the effects of climate change and biophysical constraints. The assessment of agronomic practices across agroecological zones (AEZs) is limited by inadequate data quality, hindering a precise evaluation of maize yield on a large scale. In this study, we employed the DSSAT-CERES-Maize crop model (where CERES is Crop Environment Resource Synthesis and DSSAT is Decision Support System for Agrotechnology Transfer) to investigate the impacts of different agronomic practices on maize yield across different AEZs in two counties of Kenya. The model was calibrated and evaluated with observed grain yield, biomass, leaf area index, phenology, and soil water content from 2-year experiments. Remote sensing (RS) images derived from the Sentinel-2 satellite were integrated to delineate maize areas, and the resulting information was merged with DSSAT-CERES-Maize yield simulations. This facilitated a comprehensive quantification of various agronomic measures at pixel scales. Evaluation of agronomic measures revealed that sowing dates and cultivar types significantly influenced maize yield across the AEZs. Notably, AEZ II and AEZ III exhibited elevated yields when implementing combined practices of early sowing and cultivar H614. The impacts of optimal management practices varied across the AEZs, resulting in yield increases of 81, 115, and 202 kg ha−1 in AEZ I, AEZ II, and AEZ III, respectively. This study underscores the potential of the CERES-Maize model and high-resolution RS data in estimating production at larger scales. Furthermore, this integrated approach holds promise for supporting agricultural decision-making and designing optimal strategies to enhance productivity while accounting for site-specific conditions.
An assessment of non-timber forest products (NTFPs) utilization on rural livelihoods in Ini local government area of Akwa Ibom State, Nigeria
Creators: name: Iqbal, Zahid
name: F.O. Ogundele1
name: E.A. Utin2
name: A.I. Iwara2
name: G. N. Njar3
name: T.N. Deekor4
Publisher: name: figshare
Year: 2015
Subjects: subject: Education
subject: Environmental Humanities
subject: Botany
subject: Environmental Science
subject: Environmental Chemistry
subject: Ecology
subject: FOS: Biological sciences

description: The study examined the contribution of non-timber forest products (NTFPS) utilization on rural livelihood in Ini Local Government Area of Akwa Ibom State, Nigeria. The specific objective was to investigate the utilization of NTFPs and ascertains it effects on rural livelihood. Data were obtained through the administration of 373 copies of structured questionnaire to 10 communities with large portion of natural rainforest. Data obtained were analysed using descriptive and inferential statistical tools. The multiple regression result showed that the utilization of NTFPs was significantly influenced by socio-economic factors (age, gender, income and educational level) (p<0.05). The t-statistic result revealed that the utilization of NTFPs greatly contributed to rural livelihood such as cooking, medical treatment, roofing materials, craft making and income generation (p<0.01). The study revealed that 96.7 per cent of forest lands in the area were owned by individuals, families and communities, while only 3.3 per cent was owned either by the state or local government. The study suggests the domestication of economically valuable products be given priority at the local level as well as improves trade in NTFPs.
The Concept of pq-Functions
Creators: name: Hassani, Mohamed Elmansour
Publisher: name: figshare
Year: 2019
Subjects: subject: Computation Theory and Mathematics
subject: FOS: Computer and information sciences

description: In this article we study the concept of pq-functions which should regard as an extension of prior work relating to pq-radial functions. Here, our main aim is to generalize this concept to the field of complex numbers. As direct consequences, new kind of (partial) differential equations, polynomials, series and integrals are derived, and Joukowski function is generalized.
Additional file 1 of Combining adult with pediatric patient data to develop a clinical decision support tool intended for children: leveraging machine learning to model heterogeneity
Creators: name: Sabharwal, Paul
name: Hurst, Jillian H.
name: Tejwani, Rohit
name: Hobbs, Kevin T.
name: Routh, Jonathan C.
name: Goldstein, Benjamin A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Statistics
subject: FOS: Mathematics

description: Additional file 1: Supplemental Table 1. Predictor Variables used in each model. Supplemental Table 2. CPT Code Ranges Used (286, including None and Other). Supplemental Table 3. Performance of models on pediatric patients (n = 1428) during the COVID period (March 2020 – January 2022). Supplemental Figure 1. ROC plots for ICU and Ventilator models based on training population and model type.
Laporan Praktikum Botani Tumbuhan Tinggi Divisi Pinophyta (Nikmah Hidayah)
Creators: name: Nikmah Hidayah
Publisher: name: Zenodo
Year: 2020

description: Assalamualaikum wr. wb. Ini Laporan Praktikum 1 Divisi Pinophyta saya Nikmah Hidayah (180101111084) Semoga bermanfaat, terima kasih.
Laporan Praktikum Botani Tumbuhan Tinggi Divisi Magnoliophyta, Kelas Magnoliopsida, Anak Kelas Magnoliidae (Nikmah Hidayah)
Creators: name: Nikmah Hidayah
Publisher: name: Zenodo
Year: 2020

description: Assalamualaikum wr. wb. Ini Laporan Praktikum Botani Tumbuhan Tinggi Divisi Magnoliophyta, Kelas Magnoliopsida, Anak Kelas Magnoliidae saya Nikmah Hidayah (180101111084) Semoga bermanfaat, terima kasih.
Additional file 1 of Successful use of dalbavancin in the treatment of gram positive blood stream infections: a case series
Creators: name: Evins, Connor
name: Lancaster, Harrison
name: Schnee, Amanda E.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1: Table S1. Characteristics of patients treated with dalbavancin
Optimal feature selection for improved ML based reconstruction of Global Terrestrial Water Storage Anomalies
Creators: name: Mandal, Nehar
name: Das, Prabal
name: Chanda, Kironmala
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 370704
subject: Surface water hydrology

description: # The file 'Mississippi_JPL_grids.csv' contains the latitude and longitude coordinates of all JPL mascon grid points within the Mississippi River basin.# In the 'Model_Input' folder, the grid-wise file serves as the input and target dataset necessary for running the machine learning models for a specific grid.# The grid-wise file in the 'BN_Predictors' folder comprises optimal predictors identified by the Bayesian Network (BN) for a specific grid.# For very few grids BN is not identifying any predictors or only one predictor. Grids with zero or one optimal predictor identified by BN are trained using all 15 potential predictors ('P', 'T', 'NOAH_TWSA', 'CLSM_TWSA', 'DMI', 'NAO', 'ONI', 'P1', 'T1', 'NOAH_TWSA_1', 'CLSM_TWSA_1', 'P2', 'T2', 'NOAH_TWSA_2', 'CLSM_TWSA_2').# Forecast_Results: The folder contains grid-wise forecast time series# Hindcast_Results: The folder contains grid-wise hindcast time seriesNote: In the later stage of publication, the complete global dataset will be made available publicly.
3D Construction Printing
Creators: name: Ranjha, Sagheer
name: Kulkarni, Ambarish
name: Sanjayan, Jay
Publisher: name: Swinburne
Year: 2024

description: Globally construction industry has highest carbon impacts which accounts for 40% of global energy consumption, 38% of carbon emission as well as 12% of water eutrophication. Thus, there is great demand for decarbonisation in this industry. 3D printing or additive manufacturing has emerged as a potential solution to reduce the energy demands, water wastage and carbon emissions. 3D printing in construction context is an innovative technology that creates 3D objects by reproducing physical objects with continuous layers. Recently, from polymer and steel the industry has leaped forward using concrete with potential applications in the construction engineering. Anecdotally, these technologies proved to reduce production time, minimise wastage and reduce labour costs significantly. The current challenges in 3D printing commercialisation, are lack of standard building codes, large scale investment, functional performance and architectural designs. In this research, concrete prototypes were printed for tests and a comparative study was established with the conventional manufactured concrete to analyse performance standards, cost benefits and lifecycle assessments. Future scope of this research is to develop a performance standards based on benefits for large scale implementation in construction industry.
Additional file 2 of Successful use of dalbavancin in the treatment of gram positive blood stream infections: a case series
Creators: name: Evins, Connor
name: Lancaster, Harrison
name: Schnee, Amanda E.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 2: Table S2. Patient demographics
Thermal decontamination of sewage sludge
Creators: name: Dubova, L.
name: Strunnikova, N.
name: Cielava, N.
name: Alsina, I.
name: Kassien, O.
name: Bekker, A.
Publisher: name: Agronomy Research
Year: 2020
Subjects: layer thickness
movement speed
organic fertilizers
sewage sludge
thermal disinfection
residence time
article

description: Every year a huge amount of sewage sludge is formed at municipal wastewater treatment plants. Sewage sludge contains a sufficient amount of biogenic elements and organic components, which characterizes them as possible raw materials for the production of organic fertilizers. However, direct incorporation of these sediments into the soil is impossible due to the fact that, in addition to useful organic and mineral components, they contain pathogens, viruses and helminth eggs. The aim of the study was to optimise thermal disinfection conditions for preparing of safety sewage sludge fertilizer. Laboratory studies were carried out using sediments from wastewater treatment plants of some cities. During laboratory experiments, the conditions for thermal disinfection of sediments – the thickness of the sediment layer, the air temperature in the disinfection furnace, and the treatment time of the sediment – were determined. When conducting industrial tests of a conveyor-type sediment decontamination furnace, the operating conditions of the furnace were determined, i.e., the temperature regimes of the sludge heating zone, the decontamination zone and the cooling zone, and the optimum parameters of the sludge layer thickness on the conveyor and the conveyor speed were determined.
Response of barley to liming of acid soils collected from different land use systems of Western Oromia, Ethiopia
Creators: name: Iqbal, Zahid
name: Achalu Chimdi1*,
name: Heluf Gebrekidan2
name: Kibebew Kibret2
name: Abi Tadesse3
Publisher: name: figshare
Year: 2015
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences
subject: Environmental Chemistry
subject: Education
subject: Environmental Humanities

description: Barley (Hordeum vulgare L.) is one of the acid soil sensitive but genetically diverse cereal crop in Ethiopia. A green house pot experiment was conducted to assess the response of barley variety (HB-1307) grown on acid soils to application rates and particle sizes of lime. The study employed a randomized complete block design of three-way factorial arrangement of three land use types (forest, grazing and cultivated lands), six rates of lime (0, 2, 4, 6, 8 and 10 tons ha-1) and two particle sizes (50 and 100 mesh) of lime in three replications. Plant height, fresh and dry biomass, grain yield, harvest index and plant P uptake were measured and subjected to analysis of variance using SAS software to evaluate the treatment effects. Maximum mean barley yield components for both 50 and 100 mesh lime particle sizes (LPS) were obtained at 6 t ha-1 of lime rate on the forest land followed by 8 and 10 t ha-1, respectively, on grazing and cultivated lands. The mean square estimate revealed highly significant (P < 0.001) between lime rates and land uses on barley height, fresh and dry biomass, harvest index and P uptake whilst it showed an insignificant (P > 0.05) interaction effects between lime rates and lime particle sizes. There was significant ( P< 0.05) interactions between lime rates, lime particle sizes and land use types on barley height, dry biomass and harvest index while insignificant (P > 0.05) on fresh biomass, grain yields and harvest index. The study showed, plant height, fresh and dry biomass increased due to liming of acidic soils of the three different land uses. However, response pattern of these traits to varying lime application rates varied from one land use to the other.
Additional file 1 of Diagnosis, management, and outcome of cardiac sarcoidosis and giant cell myocarditis: a Swedish single center experience
Creators: name: Bobbio, Emanuele
name: Hjalmarsson, Clara
name: Björkenstam, Marie
name: Polte, Christian L.
name: Oldfors, Anders
name: Lindström, Ulf
name: Dahlberg, Pia
name: Bartfay, Sven-Erik
name: Szamlewski, Piotr
name: Taha, Amar
name: Sakiniene, Egidija
name: Karason, Kristjan
name: Bergh, Niklas
name: Bollano, Entela
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Additional file 1. Table S1. Clinical and demographic characteristics at presentation of the patients included in the survival analysis.
The disparities of healthcare access for adults with autism spectrum disorder: Protocol for a systematic review
Creators: name: Calleja, Shenae
name: Islam, Amirul
name: Kingsley, Jonathan
name: McDonald, Rachael
Publisher: name: Swinburne
Year: 2024

description: Introduction: Adults living with autism AQ4 spectrum disorder (ASD) can experience many factors that may impact their everyday lives. Striving for optimal health and enduring a healthy lifestyle comes with the ability to access appropriate healthcare services, yet adults with ASD have unmet healthcare needs. The barriers and enablers of healthcare access for adults with ASD remain unclear. We will conduct a systematic review to explore what is currently known about healthcare access for adults with ASD, this will determine the level and appropriateness of access to healthcare services to better support the lives of adults with ASD.
Method and analysis: The systematic review will report on all studies that include quantitative, qualitative, and mixed-methods designs that consider healthcare access for adults with ASD. We will search 5 databases: EBSCOhost, Scopus, PubMed, the Cochrane Library, and Web of Science. The Mixed Methods Appraisal Tool (MMAT) will be used to assess quality of articles and the Cochrane RoB 2.0 Tool will be used to assess for bias. Clarifying the evidence in this area will be important for future research directions when developing and piloting health interventions for researchers and healthcare clinicians in the field.
Ethics and dissemination: There are no human participants, data, or tissue being directly studied for the purposes of the review; therefore, ethics approval and consent to participate is not applicable.
Registration and Status: PROSPERO 2018 CRD42018116093.
Supersubstantival composition as identity
Creators: name: Manuel, Travis
Publisher: name: University of St Andrews
Year: 2021

description: The most popular form of supersubstantivalism claims that each material object is identical to its location. Composition as Identity (CAI) claims that each material object is identical to its parts taken together. These two theories are crying out for unification: they share many commitments, they can solve problems for each other, and the theory that results from their combination is elegant and powerful. Elegant because it unifies three phenomena (composition, location, and identity) and two different theories (supersubstantivalism and CAI). Powerful because it puts one relation (identity) to a great deal of work, using it to offer answers to the general and special composition questions as well as solutions to various mysteries about the relationship between material objects and spacetime. The work of this thesis is to combine supersubstantivalism and CAI into a new theory. I call this new theory supersubstantival composition as identity. Or, super-CAI, for short. In the course of advocating for super-CAI, I offer some new advances for related literature. I show how to make a restricted view of composition consistent with CAI and with supersubstantivalism. I show that supersubstantivalism is consistent with failures of harmony. I develop a method of relativising is one of predications to ways of counting. And I explain why colocation of physically discernible material objects is (at least physically) impossible. All while offering a systematic defence of a novel theory of composition and location.
Circling a square: The geometry of Beinecke MS408 folio 86v and how to construct the scaffold of the Rosette map with compass and straightedge
Creators: name: Wastl, Juergen
Publisher: name: figshare
Year: 2015
Subjects: subject: History
subject: Philosophy
subject: FOS: Philosophy, ethics and religion

description: This paper describes two possibilities on how to construct the scaffold of the Beinecke MS408 f86v ‘Rosette map’ (i) in a simple fashion and (ii) in only a few step process with compass and straightedge: A ‘circle’-based process requires four straight lines. Following onto that two circle settings (linked via golden ratio) are sufficient to produce the main scaffold in f86v.
Simple though it is, the geometric design leads to a highly symmetric ‘picture’ with a further pattern worth mentioning: the medieval mind’s love of squaring the circle. Literally, circling the square is easily achieved in this construction. Comparison and overlays with circles and squares in other medieval diagrams and maps suggests that this way of constructing diagrams can be applied to not only the Rosette map, but to other contemporary diagrams and maps, too.
The important question, if the use of the golden ratio (1.618) is deliberate or a coincidence, can’t be unequivocally answered, however the overlays described in this paper indicate the knowledge and the use of the application of golden ratio based geometric construction in the Rosette map in at least two instances:
The diameter of the central disc itself (in comparison to the overall folio’s dimension) and
the ratio of the central disc versus the eight outer circles.
These two processes give rise to the position of the outer circles in relation to the central disc (via the ‘circle’-based construction)
Additional file 2 of Diagnosis, management, and outcome of cardiac sarcoidosis and giant cell myocarditis: a Swedish single center experience
Creators: name: Bobbio, Emanuele
name: Hjalmarsson, Clara
name: Björkenstam, Marie
name: Polte, Christian L.
name: Oldfors, Anders
name: Lindström, Ulf
name: Dahlberg, Pia
name: Bartfay, Sven-Erik
name: Szamlewski, Piotr
name: Taha, Amar
name: Sakiniene, Egidija
name: Karason, Kristjan
name: Bergh, Niklas
name: Bollano, Entela
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Additional file 2. Table S2. Findings from electrocardiography, echocardiography, and cardiovascular magnetic resonance imaging examinations at presentation of the patients included in the survival analysis.
GrainSizeTools script manual
Creators: name: Lopez-Sanchez, Marco A.
Publisher: name: figshare
Year: 2015
Subjects: subject: Solid Earth Sciences
subject: Geophysics
subject: FOS: Earth and related environmental sciences
subject: Geology
subject: Computer Software
subject: FOS: Computer and information sciences
subject: Mineralogy

description: This is the manual fo the GrainSizeTools script. GrainSizeTools script is a free open-source cross-platform script written in Python that provides a number of tools with the aim of characterizing the grain size and the actual population of grain sizes in dynamically recrystallized rocks. The script is suitable to use in paleopiezometry studies, using different 1D grain size measures, as well as to derive the actual 3D population of grain sizes from 2D data (i.e. thin sections). The script only requires the previous measurement of the grain sectional areas from a thin section. There is no need of previous knowledge of Python language to use the script and get the results. For advanced users, the script is organized in a modular way using Python functions, which facilitates to modify, reuse or extend the code if needed.
Additional file 1 of PRObiotics and SYNbiotics to improve gut health and growth in infants in western Kenya (PROSYNK Trial): study protocol for a 4-arm, open-label, randomised, controlled trial
Creators: name: Otiti, Mary Iwaret
name: Kariuki, Simon
name: Wang, Duolao
name: Hall, Lindsay J.
name: Ter Kuile, Feiko O.
name: Allen, Stephen
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Antibiotic sensitivity of probiotic organisms.
title: Η μαιευτική φροντίδα της εγκύου με καρκίνο
title: Midwifery care of women with cancer
titleType: AlternativeTitle
Creators: name: Λαζάρου, Ευαγγελία
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Καρκίνος στην εγκυμοσύνη
Μαιευτική διαχείριση
Περιγεννητική διαχείριση
Νεογνικά αποτελέσματα

description: Η συνύπαρξη κύησης και καρκίνου δυστυχώς επιπλέκει 1:1000-1:3000 κυήσεις. Η πρόοδος τόσο της μαιευτικής όσο και της ογκολογίας επιτρέπει την αντιμετώπιση της νόσου κατά τη διάρκεια της κύησης σε ορισμένους τύπους καρκίνων. Τα αυξανόμενα στοιχεία δείχνουν ότι πολλές χειρουργικές και συστηματικές θεραπείες μπορούν να είναι αποτελεσματικές για τα ογκολογικά αποτελέσματα της μητέρας χωρίς σημαντική βλάβη στο αναπτυσσόμενο έμβρυο. Ωστόσο, η βελτιστοποίηση της θεραπείας του καρκίνου και η ελαχιστοποίηση της βλάβης στο έμβρυο συχνά εξαρτώνται από την έκταση της νόσου, τις επιλογές θεραπείας που απαιτούνται καθώς και από την ηλικία κύησης του εμβρύου. Η τρέχουσα έρευνα έχει επικεντρωθεί κυρίως στη σκοπιμότητα και την ασφάλεια της ογκολογικής θεραπείας σε γυναίκες με καρκίνο και οι αναφορές με μαιευτική άποψη για αυτό το θέμα είναι σπάνιες. Σε αυτήν την ανασκόπηση, περιγράφουμε τις διάφορες πτυχές της μαιευτικής και περιγεννητικής διαχείρισης των γυναικών με καρκίνο και παρουσιάζουμε τη τρέχουσα δημοσιευμένη βιβλιογραφία σχετικά με τις εμβρυϊκές και νεογνικές επιπτώσεις της διάγνωσης και της θεραπείας του καρκίνου κατά τη κύηση.
title: Building a Policy Framework for Wild Rice Restoration in the Great Lakes Region
Creators: name: Bulmash, Brooke
name: Fornes, Margaret
name: Hedgecock, Shiloh
name: Johnson, McKenna
name: Merolle, Abigail
name: Piatt, Ryan
Publisher: name: University of Michigan
Year: 2025
Subjects: subject: stewardship
subject: restoration
subject: Sovereignty

description: The communities served by the 35 Tribal nations and three treaty organizations in the Great Lakes region have goals to maintain and restore Tribal relationships with wild rice. To achieve this goal, they have developed research and education programs and engaged in policy advocacy. For each Great Lakes Tribe, including two relocation tribes, wild rice has significance, including, in the case of many Tribes, for cultural, health or ecological reasons. Each Tribe or related Tribal organization has a long history of collaborations with - but also, in some cases, resistance to - local, state, and federal governments, and organizations like universities to further research and advocacy on environmental initiatives. With few exceptions, wild rice stewardship programs and initiatives do not engage in regional coordination across the boundaries of all 35 Tribal nations and ceded territories in what is now Minnesota, Wisconsin, and Michigan. To support the development of a regional coordinated effort to steward wild rice, this report utilizes a framework consisting of a regional ecological analysis, policy advocacy and legal protections, and a repository of existing stewardship strategies. We also developed a participatory mapping application and a landscape analysis of a case study site in Munuscong Bay. This project intends to contribute, at an early stage of planning, to the base of information needed to envision a regional coordination plan. Through an ecology-based literature review, a review of policies and case law, existing restoration efforts, interviews with wild rice stewards, and an analysis of land use methodologies across the ceded territories, this project will bring together existing strategies for wild rice restoration and support regional coordination for wild rice restoration and stewardship.
Additional file 1 of Oxaliplatin- versus cisplatin-based regimens for elderly individuals with advanced gastric cancer: a retrospective cohort study
Creators: name: Chinen, Takashi
name: Sasabuchi, Yusuke
name: Matsui, Hiroki
name: Yamaguchi, Hironori
name: Yasunaga, Hideo
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: Additional file 1: Supplemental Table 1. Drug utilization of patients from Kumamoto and Tochigi prefecture data before propensity score weighting.
title: Η Αυτοπεποίθηση της Μητέρας ως Παράγοντας Επίτευξης Μακροχρόνιου Θηλασμού
title: Maternal self-esteem and self-efficacy as factors affecting maternal long-term breastfeeding
titleType: AlternativeTitle
Creators: name: Αγαλιανού, Αναστασία
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Αυτοαποτελεσματικότητα για τον μητρικό θηλασμό
Κλίμακα Αξιολόγησης Αυτοαποτελεσματικότητας
Αυτοεκτίμηση της μητέρας
Διάρκεια θηλασμού

description: Εισαγωγή: Ο μητρικός θηλασμός αναγνωρίζεται ευρέως ως η βέλτιστη μέθοδος σίτισης για τα βρέφη παρέχοντας πολυάριθμα οφέλη για την υγεία, τόσο για το βρέφος όσο και για τη μητέρα. Έχουν παρατηρηθεί πολυάριθμοι παράγοντες που επηρεάζουν την επιτυχία του και σήμερα η αυτοεκτίμηση της μητέρας και ειδικότερα η αυτοαποτελεσματικότητα έχουν αναγνωριστεί επίσης ως σημαντικοί καθοριστικοί παράγοντες. Για το σκοπό αυτό είναι σημαντικό να ληφθεί υπόψη ο ρόλος της μητρικής αυτοεκτίμησης στην επίτευξη και στη διατήρηση του μητρικού θηλασμού Μέθοδοι: Η παρούσα ανασκόπηση της τρέχουσας ιατρικής βιβλιογραφίας έχει ως στόχο τη διερεύνηση της συσχέτισης μεταξύ της αυτοαποτελεσματικότητας της μητέρας και της διάρκειας του θηλασμού. Επιλέχθηκαν συνολικά 23 άρθρα για εκτενή ανασκόπηση μετά από διαδικτυακή αναζήτηση της σχετικής βιβλιογραφίας που χρονολογείται από το 2009 και μετά. Όλα τα άρθρα αναλύθηκαν εντοπίζοντας βασικά θέματα, προσεγγίσεις και συμπεράσματα σχετικά με την προσέγγιση του θηλασμού και την αυτοαποτελεσματικότητα της μητέρας. Αποτελέσματα: Τα ευρήματα σταθερά κατέδειξαν ότι υψηλότερα επίπεδα αυτοαποτελεσματικότητας της μητέρας σχετίζονταν με καλύτερα αποτελέσματα θηλασμού, συμπεριλαμβανομένης της μεγαλύτερης διάρκειας αποκλειστικού θηλασμού. Οι παρεμβάσεις που είχαν ως στοχο την ενίσχυση της αυτοαποτελεσματικότητας, όπως τα εκπαιδευτικά προγράμματα και η συμβουλευτική, διαπιστώθηκε ότι ήταν αποτελεσματικές στην ενδυνάμωση των γυναικών και στην προώθηση του μακροχρόνιου θηλασμού. Ωστόσο παρατηρήθηκε ότι η αυτοαποτελεσματικότητα της μητέρας στον θηλασμό τείνει να μειώνεται με την πάροδο του χρόνου υπογραμμίζοντας την ανάγκη για συνεχή υποστήριξη και παρεμβάσεις. Συμπεράσματα: Η αυτοαποτελεσματικότητα της μητέρας διαδραματίζει ζωτικό ρόλο στην επίτευξη των μακροπρόθεσμων στόχων του μητρικού θηλασμού. Οι παρεμβάσεις και τα προγράμματα υποστήριξης που ενισχύουν την αυτοαποτελεσματικότητα της μητέρας είναι ελπιδοφόρα για την βελτίωση των αποτελεσμάτων του θηλασμού. Η συνεχής υποστήριξη, η συμβουλευτική και η πρόσβαση σε πηγές πληροφόρησης είναι ζωτικής σημασίας για τη διατήρηση και τη βελτίωση των επιπέδων αυτοαποτελεσματικότητας. Οι επαγγελματίες υγείας και οι υπεύθυνοι φορείς θα πρέπει να εξετάσουν το ενδεχόμενο ενσωμάτωσης στρατηγικών για την ενίσχυση της αυτοεκτίμησης της μητέρας στις πρωτοβουλίες υποστήριξης του θηλασμού προκειμένου να επιτευχθούν οι επιθυμητοί στόχοι. Απαιτείται περαιτέρω έρευνα για τη διερεύνηση των πολιτισμικών και κοινωνικών επιδράσεων στη μητρική αυτοεκτίμηση και την ανάπτυξη προσαρμοσμένων παρεμβάσεων για διαφορετικούς πληθυσμούς.
Dual-Model Simple Cache (DMSC) and Triple-Model Adaptive Routing (TMAR): Multi-Model Optimization
Creators: name: Krzysztof Marciniak
Publisher: name: Zenodo
Year: 2025

description: Abstract: This paper introduces two innovative approaches for optimizing large language model query sys-tems: Dual-Model Simple Cache (DMSC) and Triple-Model Adaptive Routing (TMAR). DMSC achievesa 93.4% reduction in response time by implementing an intelligent caching mechanism using Redis, com-bining a lightweight cache model (Gemma 2 9B) with a powerful main model (Deepseek R1) to optimizerepeated queries. TMAR delivers a 35.8% reduction in average response time through complexity-basedrouting, utilizing a three-tiered architecture that intelligently directs questions based on their complexitylevel. Both systems demonstrate significant performance improvements while maintaining response quality,offering practical solutions for efficient large language model deployment.
GrainSizeTools script manual
Creators: name: Lopez-Sanchez, Marco A.
Publisher: name: figshare
Year: 2015
Subjects: subject: Solid Earth Sciences
subject: Geophysics
subject: FOS: Earth and related environmental sciences
subject: Geology
subject: Computer Software
subject: FOS: Computer and information sciences
subject: Mineralogy

description: This is the manual for the GrainSizeTools script. GrainSizeTools script is a free open-source cross-platform script written in Python that provides a number of tools with the aim of characterizing the grain size and the actual population of grain sizes in dynamically recrystallized rocks. The script is suitable to use in paleopiezometry studies, using different 1D grain size measures, as well as to derive the actual 3D population of grain sizes from 2D data (i.e. thin sections). The script only requires the previous measurement of the grain sectional areas from a thin section. There is no need of previous knowledge of Python language to use the script and get the results. For advanced users, the script is organized in a modular way using Python functions, which facilitates to modify, reuse or extend the code if needed.
Matching markets in housing and housing assistance
Creators: name: Sharam, Andrea
name: Byford, Martin
name: Karabay, Bilgehan
name: McNelis, Sean
name: Burke, Terry
Publisher: name: Swinburne
Year: 2024

description: This study identified five Australian housing markets that could be made more efficient using online technology to match highly specific ‘buyers’ and ‘sellers’. The five markets considered are: swaps in public housing; disability accessible housing; low-cost private rental housing brokerage; apartment presales for low/mid income earners; and precinct-level urban redevelopment. The research also proposed solutions to how the matching markets could best operate.
Additional file 2 of Oxaliplatin- versus cisplatin-based regimens for elderly individuals with advanced gastric cancer: a retrospective cohort study
Creators: name: Chinen, Takashi
name: Sasabuchi, Yusuke
name: Matsui, Hiroki
name: Yamaguchi, Hironori
name: Yasunaga, Hideo
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: Additional file 2: Supplemental Table 2. Drug utilisation of patients before and after propensity-score weighting.
title: Η μετασχηματιστική ηγεσία στις υπηρεσίες υγείας και η σχέση της με την ικανοποίηση από την εργασία
title: Transformational leadership in health services and its relationship with job satisfaction
titleType: AlternativeTitle
Creators: name: Σφακτού, Παναγιώτα
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Μετασχηματιστική ηγεσία
Υπηρεσίες υγείας
Εργασιακή ικανοποίηση

description: Η μετασχηματιστική ηγεσία, είναι ένα ιδιαίτερο θέμα που έχει απασχολήσει αρκετούς ερευνητές. Θεωρείται ως η πιο γνωστή μορφή εξουσίας, καθώς φαίνεται να σχετίζεται με αυξημένα επίπεδα εργασιακής ικανοποίησης, όσον αφορά τις μονάδες υγείας. Παρόλα αυτά η εφαρμογή της θεωρείται δύσκολη, καθώς απαιτούνται διοικητικές γνώσεις. Επίσης είναι απαραίτητο να διασφαλιστεί ότι υπάρχουν οι απαραίτητοι οργανωτικοί, προσωπικοί, εκπαιδευτικοί και ανθρώπινοι πόροι. Σκοπός της εργασίας είναι να καταμετρηθεί ο τρόπος και ο βαθμός που επηρεάζεται η εργασιακή ικανοποίηση από την άσκηση Μετασχηματιστικής Ηγεσίας σε έναν Οργανισμό. Όσον αφορά την μεθοδολογική δομή της παρούσας εργασίας, χωρίστηκε σε δύο μέρη. Αρχικά βασίστηκε σε ανασκόπηση της βιβλιογραφίας, και στην συνέχεια σε ποσοτική διερευνητική έρευνα. Η έρευνα πραγματοποιήθηκε στο Γενικό νοσοκομείο Αττικής ΚΑΤ, όπου επαγγελματίες υγείας, συμπλήρωσαν ένα ειδικό ερωτηματολόγιο 48 ερωτήσεων. Το ερωτηματολόγιο ήταν χωρισμένο σε 3 ενότητες. Συγκεκριμένα, στην πρώτη αναγράφονται τα δημογραφικά χαρακτηριστικά των εργαζομένων, στην δεύτερη ενότητα καταγράφεται η εργασιακή ικανοποίηση ενώ η τρίτη ενότητα μιλάει για την μετασχηματιστική ηγεσία στις μονάδες υγείας. Στην συνέχεια παρατίθενται τα αποτελέσματα της έρευνας, η οποία πραγματοποιείται για την ανάγκη της παρούσας διπλωματικής εργασίας. Συγκεκριμένα καταγράφεται, η μεθοδολογία, το δείγμα και το ερευνητικό εργαλείο της έρευνας. Έπειτα, επιτυγχάνεται ανάλυση των αποτελεσμάτων και τα συναφή συμπεράσματα.
Additional file 1 of Foraging on the wing for fish while migrating over changing landscapes: traveling behaviors vary with available aquatic habitat for Caspian terns
Creators: name: Rueda-Uribe, C.
name: Lötberg, U.
name: Åkesson, S.
Publisher: name: figshare
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Additional file 1. Supplementary figures.
GrainSizeTools script manual
Creators: name: Lopez-Sanchez, Marco A.
Publisher: name: figshare
Year: 2016
Subjects: subject: Solid Earth Sciences
subject: Geophysics
subject: FOS: Earth and related environmental sciences
subject: Geology
subject: Computer Software
subject: FOS: Computer and information sciences
subject: Mineralogy

description: This is the manual for the GrainSizeTools script. GrainSizeTools script is a free open-source cross-platform script written in Python that provides a number of tools with the aim of characterizing the grain size and the actual population of grain sizes in dynamically recrystallized rocks. The script is suitable to use in paleopiezometry studies, returning different 1D grain size measures, as well as to derive the actual 3D population of grain sizes from thin sections using two methods: the Saltykov and the two-step methods. The script only requires the previous measurement of the grain sectional areas from a thin section. There is no need of previous knowledge of Python language to use the script and get the results. For advanced users, the script is organized in a modular way using Python functions, which facilitates to modify, reuse or extend the code if needed.
Exogenous management in autonomic service compositions
Creators: name: Colman, Alan
Publisher: name: Swinburne
Year: 2024

description: This paper proposes that software architectures that support autonomic service-oriented computing need to have an exogenous management structure. Exogenous management regards autonomicity as a property of relationships between elements, rather than a property of the elements themselves. We explain the concept of exogenous management, and show how a number of desirable attributes that support autonomicity flow from this approach. These attributes include self-management; separability; recursive composition; and grounding through the monitoring of interactions. We will show how these attributes help enhance the adaptability and control the complexity of context-aware compositions of services. We then discuss how this exogenous approach to management has been implemented in the ROAD (Role-oriented Adaptive Design) programming framework. This framework is extended by software developers to create service compositions whose level of autonomicity can be incrementally modified at runtime.
IMPACTS OF FOREIGN DIRECT INVESTMENT ON INDIAN RETAIL BAZAAR: AN EMPIRICAL STUDY
Creators: name: Anis Ur Rehman, Faraz Ahmad Abbasi
Publisher: name: TuEngr.com
Year: 2020
Subjects: Single brand retailing
Organized retailing
Single-brand stores
Indian retail sector
Managers' perception of FDI
FDI impacts.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 6, 11A06M: 1-11
Constance Lytton: Living for a Cause
Creators: name: Scott, David
name: Spears, Faith
Publisher: name: figshare
Year: 2015
Subjects: subject: Law
subject: FOS: Law
subject: Sociology
subject: FOS: Sociology

description: The life of prison reformer Constance Lytton
GrainSizeTools script manual
Creators: name: Lopez-Sanchez, Marco A.
Publisher: name: figshare
Year: 2016
Subjects: subject: Solid Earth Sciences
subject: Geophysics
subject: FOS: Earth and related environmental sciences
subject: Geology
subject: Computer Software
subject: FOS: Computer and information sciences
subject: Mineralogy

description: This is the manual for the GrainSizeTools script v1.2. GrainSizeTools script is a free open-source cross-platform script written in Python that provides several tools to characterize the grain size from thin sections. The script is suitable to use for paleopiezometry (paleowattmetry) studies and to derive the actual 3D grain size distribution using the Saltykov and the two-step methods. The script only requires measuring the grain sectional areas from a thin section in advance and does not require a previous experience with Python programming language. For users with coding skills, the script is organized in a modular way using Python functions, which facilitates to modify, reuse or extend the code if needed.
G4S Agm 2014
Creators: name: Scott, David
Publisher: name: figshare
Year: 2015
Subjects: subject: Law
subject: FOS: Law
subject: Sociology
subject: FOS: Sociology

description: An account of the Reclaim Justice Network protest and interventions at the Annual General Meeting of G4S in 2014
Additional file 1 of The educational value of an audience response system use in an Iraqi medical school
Creators: name: Tuma, Faiz
name: Majeed, Husam
name: Blebea, John
name: Nassar, Aussama
name: Durchholz, William C.
name: Schofield, Susie
Publisher: name: figshare
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology

description: Additional file 1.
GrainSizeTools script manual
Creators: name: Lopez-Sanchez, Marco A.
Publisher: name: figshare
Year: 2017
Subjects: subject: Solid Earth Sciences
subject: Geophysics
subject: FOS: Earth and related environmental sciences
subject: Geology
subject: Computer Software
subject: FOS: Computer and information sciences
subject: Mineralogy

description: This is the manual for the GrainSizeTools script v1.3. GrainSizeTools script is a free open-source cross-platform script written in Python that provides several tools to visualize and characterize the grain size from thin sections. The script is suitable to use for paleopiezometry (paleowattmetry) studies and to derive the actual 3D grain size distribution using the Saltykov and the two-step methods. The script only requires measuring the grain sectional areas from a thin section and does not require a previous experience with Python programming language (see documentation). For users with coding skills, the script is organized in a modular way using Python functions, which facilitates to modify, reuse or extend the code if needed.
LAPORAN 1
Creators: name: Fazry
Publisher: name: Zenodo
Year: 2020

description: Asaalamualaikum wr wb ibu. ini ulun bu fazry. ini file laporan praktikum 1 botani tumbuhan tinggi dan juga file hasil pengamatannya bu. bentukl filenya PDF bu hehe soalnya takut berantakan kalo bentuk filenya word. mohon maaf ya bu atas kekurangannya bu. terima kasih banyak ibu.
THE INFLUENCE OF FINANCIAL SECTOR REFORMS IN ACCESS TO CREDIT IN NIGERIA
Creators: name: Eke Robert, Ike PhD, FCA
name: Jegbefume, Samuel Onyemaechi
Publisher: name: ayden journals
Year: 2025
Subjects: Credit Allocation, Interest rate, Credit Guaranty Schemes, Financial Inclusion, Financial Reforms

description: This study investigated the influence of financial sector reforms on access to credit in Nigeria. The research aimed to examine the effects of credit allocation policies, interest rate policies, credit guarantee schemes, and financial inclusion initiatives on access to credit. Employing an ex post facto research design, the study utilized secondary time-series data from the Central Bank of Nigeria (CBN) spanning 2020 to 2024. Multiple linear regression was used to analyze the relationships between the dependent variable (access to credit) and the independent variables. The findings revealed no statistically significant relationship between financial sector reforms (credit allocation policies, interest rate policies, credit guarantee schemes, and financial inclusion initiatives) and access to credit. The regression model demonstrated a poor fit, explaining only a small and statistically insignificant portion of the variance in access to credit. Furthermore, none of the individual predictor variables exhibited a significant relationship with the dependent variable. These results contradict existing literature suggesting a significant relationship between these factors and credit access. The study concludes that the examined financial interventions, as measured in this model, did not demonstrate a significant impact on access to credit in Nigeria during the study period. It recommends future research explore other potentially influential factors, including qualitative measures, alternative measures of financial inclusion, and the broader economic context, while also addressing potential limitations of the current study such as measurement issues, multicollinearity, and sample size.