cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The use of statins was associated with reduced COVID-19 mortality: a systematic review and meta-analysis
Creators: name: Wu, Kuan-Sheng
name: Lin, Pei-Chin
name: Chen, Yao-Shen
name: Pan, Tzu-Cheng
name: Tang, Pei-Ling
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Statins are widely used to treat people with metabolic and cardiovascular disorders. The effect of statins on coronavirus disease 2019 (COVID-19) is unclear. To investigate the association between statins and COVID-19 outcomes and, if possible, identify the subgroup population that benefits most from statin use. A systematic review and meta-analysis of published studies that included statin users and described COVID-19 outcomes through 10 November 2020. This study used the generic inverse variance method to perform meta-analyses with random-effects modelling. The main outcomes were evaluation of the need for invasive mechanical ventilator (IMV) support, the need for intensive care unit (ICU) care and death. All outcomes were measured as dichotomous variables. A total of 28 observational studies, covering data from 63,537 individuals with COVID-19, were included. The use of statins was significantly associated with decreased mortality (odds ratio [OR] = 0.71, 95% confidence interval [CI]: 0.55–0.92, I2=72%) and the need for IMV (OR = 0.81, 95% CI: 0.69–0.95, I2=0%) but was not linked to the need for ICU care (OR = 0.91, 95% CI: 0.55–1.51, I2=66%). Subgroup analysis further identified five types of studies in which statin users had even lower odds of death. The use of statins was significantly associated with a reduced need for IMV and decreased mortality among individuals with COVID-19. Statins may not need to be discontinued because of concern for COVID-19 on admission. Further randomized controlled trial (RCTs) are needed to clarify the causal effect between statin use and severe COVID-19 outcomes.Key messagesParticipants in five types of studies were shown to have even lower odds of death when taking statins.The use of statins was significantly associated with a reduced need for invasive mechanical ventilation and decreased all-cause mortality among individuals with COVID-19. However, statin use did not prevent participants from needing care in the intensive care unit.The results justify performing randomized controlled trials (RCTs) to validate the benefits of statins on COVID-19 outcomes. Participants in five types of studies were shown to have even lower odds of death when taking statins. The use of statins was significantly associated with a reduced need for invasive mechanical ventilation and decreased all-cause mortality among individuals with COVID-19. However, statin use did not prevent participants from needing care in the intensive care unit. The results justify performing randomized controlled trials (RCTs) to validate the benefits of statins on COVID-19 outcomes.
A: Stereoplots from figure 2. Archaean basin margin geology and crustal evolution: an East Pilbara traverse
Creators: name: Nijman, Wouter
name: Kloppenburg, Armelle
name: Vries, Sjoukje T. De
Publisher: name: Geological Society of London
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary figure a: Stereoplots from figure 2.
2020_Aguilar-Lleyda_Lemarchand_deGardelle
Creators: name: Aguilar-Lleyda, David
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Psychiatry and Psychology
subject: Medicine and Health Sciences
subject: Experimental Analysis of Behavior
subject: Cognitive Psychology
subject: Cognition and Perception
subject: Behavior and Behavior Mechanisms
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Psychological Phenomena and Processes

description: Repository for the project 'Confidence as a priority signal'
Additional file 1 of Tumor necrosis factor-inducible gene 6 protein and its derived peptide ameliorate liver fibrosis by repressing CD44 activation in mice with alcohol-related liver disease
Creators: name: Han, Jinsol
name: Lee, Chanbin
name: Jeong, Hayeong
name: Jeon, Seunghee
name: Lee, Myunggyo
name: Lee, Haeseung
name: Choi, Yung Hyun
name: Jung, Youngmi
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Cancer

description: Additional file 1: Supplementary Figure 1. Pharmacokinetic properties of TSG-6 in mice with acute ALD. Supplementary Figure 2. Mice have liver injury with fibrosis at 9 weeks of Lieber–DeCarli alcohol liquid diet. Supplementary Figure 3. Vehicle treatment rarely impacts pathophysiological response of the liver to the diet feeding. Supplementary Figure 4. Liver fibrosis is induced by chronic consumption of EtOH in regardless of vehicle injection. Supplementary Figure 5. Localization of nuclear CD44ICD and α-SMA expression in TSG-6-treated human pHSCs. Supplementary Figure 6. Analysis of MMP14 expression in liver cells and ALD mice. Supplementary Figure 7. Design of peptides mimicking TSG-6 and inhibitory action of the peptide # 4 on HSC activation. Supplementary Figure 8. Localization of nuclear CD44ICD and α-SMA expression in YJ-given human pHSCs. Supplementary Figure 9. TSG-6 rarely impacts CD44ICD production in MMP14-suppressed human pHSCs. Supplementary Figure 10. Peptide YJ downregulated profibrotic genes in mice chronically fed EtOH. Supplementary Table 1. Primer list of qRT-PCR.
Adherence to oral anticoagulation in ischemic stroke patients with atrial fibrillation
Creators: name: Tiili, Paula
name: Leventis, Ioannis
name: Kinnunen, Janne
name: Svedjebäck, Ida
name: Lehto, Mika
name: Karagkiozi, Efstathia
name: Sagris, Dimitrios
name: Ntaios, George
name: Putaala, Jukka
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Mental Health
subject: Hematology

description: Non-vitamin K antagonist oral anticoagulants (NOAC) have superior safety and comparable efficacy profile compared to vitamin-K antagonists (VKAs), with more convenient dosing schemes. However, issues with adherence to the NOACs remain unsolved. We sought to investigate the adherence to oral anticoagulation (OAC) and baseline factors associated with poor adherence after ischaemic stroke in patients with atrial fibrillation (AF). We recruited hospitalised patients (2013–2019) from two prospective stroke registries in Larissa and Helsinki University Hospitals and invited survived patients to participate in a telephone interview. We assessed adherence with the Adherence to Refills and Medications Scale (ARMS) and defined poor adherence as a score of over 17. In addition to demographics, individual comorbidities, and stroke features, we assessed the association of CHA2DS2-VASc and SAMe-TT2R2 scores with poor adherence. Among 396 patients (median age 75.0 years, interquartile range [IQR] 70–80; 57% men; median time from ischaemic stroke to interview 21 months [IQR 12–33]; median ARMS score 17 [IQR 17–19]), 56% of warfarin users and 44% of NOAC users reported poor adherence. In the multivariable regression model adjusted for site, sex, and age, poor adherence was independently associated with tertiary education, absence of heart failure, smoking history, use of VKA prior to index stroke, and prior ischaemic stroke. CHA2DS2-VASc and SAMe-TT2R2 scores were not associated with poor adherence. Adherence was poor in half of AF patients who survived an ischaemic stroke. Independent patient-related factors, rather than composite scores, were associated with poor adherence in these patients.KEY MESSAGESAdherence was poor in half of the atrial fibrillation patients who survived an ischaemic stroke.Independent patient-related factors rather than composite scores were associated with poor adherence.The findings support the importance of recognising adherence support as a crucial part of holistic patient care recommended by recent AF guideline. Adherence was poor in half of the atrial fibrillation patients who survived an ischaemic stroke. Independent patient-related factors rather than composite scores were associated with poor adherence. The findings support the importance of recognising adherence support as a crucial part of holistic patient care recommended by recent AF guideline.
Carnet nº 14, commencé à Omuta (p. 11)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: created: 6-11-1930
External boundary control of the motion of a rigid body immersed in a perfect two-dimensional fluid
Creators: name: Glass, Olivier
name: Kolumbán, József
name: Sueur, Franck
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We consider the motion of a rigid body due to the pressure of a surrounded two-dimensional irrotational perfect incompressible fluid, the whole system being confined in a bounded domain with an impermeable condition on a part of the external boundary. Thanks to an impulsive control strategy we prove that there exists an appropriate boundary condition on the remaining part of the external boundary (allowing some fluid going in and out the domain) such that the immersed rigid body is driven from some given initial position and velocity to some final position and velocity in a given positive time, without touching the external boundary. The controlled part of the external boundary is assumed to have a nonvoid interior and the final position is assumed to be in the same connected component of the set of possible positions as the initial position.
title: ADCO, Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Cart. 31 (G 135), 549 folios, f. 0471
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0471, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0471, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Additional file 1 of Distal radial access for neuroangiography and neurointerventions: systematic review and meta-analysis
Creators: name: Wang, Jian
name: Ma, Lin
name: Cai, Huaxiu
name: Zeng, Huan
name: Pei, Fang
name: Cao, Jun
name: Li, Maogang
name: Cao, Gang
Publisher: name: figshare
Year: 2023
Subjects: subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
D: Site 1. Archaean basin margin geology and crustal evolution: an East Pilbara traverse
Creators: name: Nijman, Wouter
name: Kloppenburg, Armelle
name: Vries, Sjoukje T. De
Publisher: name: Geological Society of London
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary figure d: Site 1
Light Deflection by a Quantum Improved Kerr Black Hole Pierced by a Cosmic String
Creators: name: Jusufi, Kimet
name: Övgün, Ali
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this work, we calculate the quantum correction effects on the deflection of light in the spacetime geometry of a quantum improved Kerr black hole pierced by an infinitely long cosmic string. More precisely, we calculate the deflection angle by applying the Gauss--Bonnet theorem (GBT) to the osculating optical geometries related to the quantum improved rotating black hole in the weak limit approximation. We find that the deflection angle of light is affected by the quantum effects as well as the global topology due to the presence of the cosmic string. Besides, we have managed to find the same expression for the deflection angle in leading order terms using the geodesic equations.
description: Accepted to publish in International Journal of Geometric Methods in Modern Physics
H: Noctis Labyrinthus. Archaean basin margin geology and crustal evolution: an East Pilbara traverse
Creators: name: Nijman, Wouter
name: Kloppenburg, Armelle
name: Vries, Sjoukje T. De
Publisher: name: Geological Society of London
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary figure h: Noctis Labyrinthus
Extreme-scale motions in turbulent plane Couette flows
Creators: name: Lee, Myoungkyu
name: Moser, Robert D.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We study the size of large-scale motions in turbulent plane Couette flows at moderate Reynolds number up to $Re_τ$ = 500. Direct numerical simulation domains were as large as $100πδ\times2δ\times5πδ$, where $δ$ is half the distance between the walls. The results indicate that there are structures with streamwise extent, as measured by the wavelength, as long as 78$δ$ and at least 310$δ$ at $Re_τ$ = 220 and 500, respectively. The presence of these very long structures is apparent in the spectra of all three velocity components and the Reynolds stress. In DNS using a smaller domain, the large structures are constrained, eliminating the streamwise variations present in the larger domain. Effects of a smaller domain are also present in the mean velocity and the streamwise velocity variance in the outer flow.
description: Accepted manuscript in the Journal of Fluid Mechanics
Myelin-associated proteins are potential diagnostic markers in patients with primary brain tumour
Creators: name: Koper-Lenkiewicz, Olga M.
name: Milewska, Anna J.
name: Kamińska, Joanna
name: Sawicki, Karol
name: Chrzanowski, Robert
name: Zińczuk, Justyna
name: Reszeć, Joanna
name: Tylicka, Marzena
name: Matuszczak, Ewa
name: Matowicka-Karna, Joanna
name: Mariak, Zenon
name: Mucha, Mariusz W.
name: Pawlak, Robert
name: Dymicka-Piekarska, Violetta
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Hematology
subject: Plant Biology

description: Taking into account the possibility of myelin-associated proteins having a role in brain tumour development, the study aimed to evaluate the diagnostic usefulness of myelin-associated proteins (Nogo-A, MAG, OMgp) released into extracellular space in patients with brain tumours. Protein concentration in primary brain tumour (n = 49) and non-tumoural subjects (n = 24) was measured in cerebrospinal fluid (CSF) and serum by means of ELISA. Immunohistochemistry for IDH1-R132H was done on 5-μm thick formalin-fixed, paraffin-embedded tumour sections with the use of an antibody specific for the mutant IDH1-R132H protein. The receiver operator characteristic curve analysis showed that CSF Nogo-A and serum MAG were useful in differentiating patients with primary brain tumour from non-tumoural individuals. This was also true in the case of the separate analysis of the astrocytic tumour versus non-tumoural groups and the meningeal tumour versus non-tumoural groups. Neither Nogo-A nor MAG or OMgp concentrations were significantly different, in serum or CSF, between IDH1 wild-type astrocytic brain tumour patients compared to IDH1 mutant patients. Our results indicated the potential usefulness of CSF Nogo-A and serum MAG evaluation as circulating biomarkers of primary brain tumours. Because blood is relatively easy to obtain, future research should be conducted to explicitly indicate the value of serum MAG concentration evaluation as a brain tumour biomarker.Key messagesMyelin-associated proteins may be circulating brain tumour biomarkers.Nogo-A and MAG proteins seem to be the most useful in brain tumour diagnosis.Decreased CSF Nogo-A concentration is an adverse prognostic factor for patients’ survival. Myelin-associated proteins may be circulating brain tumour biomarkers. Nogo-A and MAG proteins seem to be the most useful in brain tumour diagnosis. Decreased CSF Nogo-A concentration is an adverse prognostic factor for patients’ survival.
Exploring the Roles of Self-Injury and Emotion Dysregulation in the Acquired Capability for Suicide
Creators: name: Jacobson, Samantha
name: Marks, Rocky
name: Law, Keyne
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Clinical Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: Data were collected in 2014 from 534 undergraduate students who completed a battery of self-report questionnaires using Qualtrics. Variables of interest are emotion dysregulation as measured by the Difficulties with Emotion Regulation Scale (Gratz & Roemer, 2004), number of NSSI methods as measured by asking participants which of 12 NSSI methods they utilize, NSSI frequency as measured by summing self-reported frequency of NSSI and self-reported lifetime frequency of NSSI, medical attention received for NSSI as measured by self-reported number of times medical attention has been received for NSSI, and acquired capability for suicide as measured by the Acquired Capability for Suicide Scale (ACSS; Van Orden et al., 2008). We hypothesize that number of NSSI methods, NSSI frequency, and medical attention received for NSSI will all independently mediate and moderate the relationship between emotion dysregulation and acquired capability for suicide in 6 separate models. We also hypothesize that number of NSSI methods and NSSI frequency will independently mediate and moderate the relationship between emotion dysregulation and medical attention received for NSSI in four separate models.
E: Coppin Gap Sector east. Archaean basin margin geology and crustal evolution: an East Pilbara traverse
Creators: name: Nijman, Wouter
name: Kloppenburg, Armelle
name: Vries, Sjoukje T. De
Publisher: name: Geological Society of London
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary figure e: Coppin Gap Sector east, geologic map interpretation on false colour satellite image.
title: ADCO, Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Cart. 29 (G 134), 996 folios, f. 0349
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0349, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0349, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Aryl hydrocarbon receptor contributes to the transcriptional program of IL-10-producing regulatory B cells.
Creators: name: Piper, Christopher JM
name: Rosser, Elizabeth C
name: Oleinika, Kristine
name: Nistala, Kiran
name: Krausgruber, Thomas
name: Rendeiro, André F
name: Aggelos Banos
name: Drozdov, Ignat
name: Villa, Matteo
name: Thomson, Scott
name: Xanthou, Georgina
name: Bock, Christoph
name: Stockinger, Brigitta
name: Mauri, Claudia
Publisher: name: The Francis Crick Institute
Year: 2020
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Regulatory B cells (Bregs) play a critical role in the control of autoimmunity and inflammation. IL-10 production is the hallmark for the identification of Bregs. However, the molecular determinants that regulate the transcription of IL-10 and control the Breg developmental program remain unknown. Here, we demonstrate that aryl hydrocarbon receptor (AhR) regulates the differentiation and function of IL-10-producing CD19+CD21hiCD24hiBregs and limits their differentiation into B cells that contribute to inflammation. Chromatin profiling and transcriptome analyses show that loss of AhR in B cells reduces expression of IL-10 by skewing the differentiation of CD19+CD21hiCD24hiB cells into a pro-inflammatory program, under Breg-inducing conditions. B cell AhR-deficient mice develop exacerbated arthritis, show significant reductions in IL-10-producing Bregs and regulatory T cells, and show an increase in T helper (Th) 1 and Th17 cells compared with B cell AhR-sufficient mice. Thus, we identify AhR as a relevant contributor to the transcriptional regulation of Breg differentiation.
G: Panorama-vsc, NE North Pole Dome. Archaean basin margin geology and crustal evolution: an East Pilbara traverse
Creators: name: Nijman, Wouter
name: Kloppenburg, Armelle
name: Vries, Sjoukje T. De
Publisher: name: Geological Society of London
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary figure g: Panorama-vsc, NE North Pole Domee
Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist.
Creators: name: Ng, Kevin W
name: Attig, Jan
name: Young, George R
name: Ottina, Eleonora
name: Papamichos, Spyros I
name: Kotsianidis, Ioannis
name: Kassiotis, George
Publisher: name: The Francis Crick Institute
Year: 2020
Subjects: subject: Model organisms
subject: Genetics & Genomics
subject: Structural Biology & Biophysics
subject: Infectious Disease
subject: Ecology,Evolution & Ethology
subject: Immunology
subject: FOS: Clinical medicine
subject: Computational & Systems Biology

description: Immune regulation is a finely balanced process of positive and negative signals. PD-L1 and its receptor PD-1 are critical regulators of autoimmune, anti-viral and anti-tumoural T cell responses. Although the function of its predominant membrane-bound form is well-established, the source and biological activity of soluble PD-L1 (sPD-L1) remain incompletely understood. Here, we show that sPD-L1 in human healthy tissues and tumours is produced by exaptation of an intronic LINE-2A (L2A) endogenous retroelement in the CD274 gene, encoding PD-L1, which causes omission of the transmembrane domain and the regulatory sequence in the canonical 3' untranslated region. The alternatively spliced CD274-L2A transcript forms the major source of sPD-L1 and is highly conserved in hominids, but lost in mice and a few related species. Importantly, CD274-L2A-encoded sPD-L1 lacks measurable T cell inhibitory activity. Instead, it functions as a receptor antagonist, blocking the inhibitory activity of PD-L1 bound on cellular or exosomal membranes.
E-learning readiness and perceived stress among the university students of Bangladesh during COVID-19: a countrywide cross-sectional study
Creators: name: Kabir, Humayun
name: Hasan, Md. Kamrul
name: Mitra, Dipak Kumar
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: The COVID-19 pandemic has compelled all educational institutions from the conventional campus-based education system to e-learning worldwide. However, adapting to this new platform, e-learning readiness may cause perceived stress among students. This study aimed to examine the association between e-learning readiness and perceived e-learning stress and the relationship between sociodemographic and e-learning related factors. A cross-sectional study was employed, where 1145 e-learning enrolled university students were surveyed. The result indicated that nearly 91% of students reported moderate (76.07%) to the higher level (14.85%) of perceived e-learning stress, whereas more than half of them (58.17%) were at the sub-optimum level of readiness. Furthermore, it was found that students with the sub-optimum level of readiness compared to optimum had a significantly higher chance of reporting moderate and high level of perceived e-learning stress. Besides, parents’ highest education, residence, students’ preference in (e-learning or learning format), and having any eye problems were associated with perceived e-learning stress. A sudden introduction of e-learning during the COVID-19 catastrophe has brought about challenges, including the students' readiness, that might exacerbate the perceived stress level in different ways. This study reported that most of the students were at sub-optimal levels of readiness and suffered from moderate to high levels of perceived e-learning stress. The findings should integrate into the education monitoring system to enhance students' coping strategies, incite readiness, straighten, and nourish existing policies.Key messagesThe moderate and higher level of e-learning stress was 76% and 15%, respectively.Here, 58% of students were at the sub-optimum level of e-learning readiness.Students’ sub-optimum level of e-learning readiness was significantly associated with the perceived moderate and high level of e-learning stress. The moderate and higher level of e-learning stress was 76% and 15%, respectively. Here, 58% of students were at the sub-optimum level of e-learning readiness. Students’ sub-optimum level of e-learning readiness was significantly associated with the perceived moderate and high level of e-learning stress.
B: Bamboo Creek growth Syncline. Archaean basin margin geology and crustal evolution: an East Pilbara traverse
Creators: name: Nijman, Wouter
name: Kloppenburg, Armelle
name: Vries, Sjoukje T. De
Publisher: name: Geological Society of London
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary figure b: Bamboo Creek growth Syncline.
Computing spectral bounds of the Heisenberg ferromagnet from geometric considerations
Creators: name: Ouyang, Yingkai
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: Mathematical Physics (math-ph)
subject: Combinatorics (math.CO)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 82B20, 81V70, 46N50, 05C50, 15A18, 15A42

description: We give a polynomial-time algorithm for computing upper bounds on some of the smaller energy eigenvalues in a spin-1/2 ferromagnetic Heisenberg model with any graph $G$ for the underlying interactions. An important ingredient is the connection between Heisenberg models and the symmetric products of $G$. Our algorithms for computing upper bounds are based on generalized diameters of graphs. Computing the upper bounds amounts to solving the minimum assignment problem on $G$, which has well-known polynomial-time algorithms from the field of combinatorial optimization. We also study the possibility of computing the lower bounds on some of the smaller energy eigenvalues of Heisenberg models. This amounts to estimating the isoperimetric inequalities of the symmetric product of graphs. By using connections with discrete Sobolev inequalities, we show that this can be performed by considering just the vertex-induced subgraphs of $G$. If our conjecture for a polynomial time approximation algorithm to solve the edge-isoperimetric problem holds, then our proposed method of estimating the energy eigenvalues via approximating the edge-isoperimetric properties of vertex-induced subgraphs will yield a polynomial time algorithm for estimating the smaller energy eigenvalues of the Heisenberg ferromagnet.
description: 25 pages, 2 figures. Merged from arxiv:1612.08259
Additional file 2: of ASC-J9® increases the bladder cancer chemotherapy efficacy via altering the androgen receptor (AR) and NF-κB survival signals
Creators: name: Huang, Chi-Ping
name: Chen, Jinbo
name: Chen, Chi-Cheng
name: Liu, Guodong
name: Zhang, Yong
name: Messing, Edward
name: Yeh, Shuyuan
name: Chang, Chawnshang
Publisher: name: figshare
Year: 2019
Subjects: Biochemistry
Space Science
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer
Hematology
Computational Biology

description: Figure S2. The representative images of apoptosis TUNEL assay in J82 (A) and TCC-SUP (B) cells. (PDF 504 kb)
Additional file 1 of PD-1+ T lymphocyte proportions and hospitalized exacerbation of COPD: a prospective cohort study
Creators: name: Xue, Hong
name: Lan, Xiuyan
name: Xue, Ting
name: Tang, Xuwei
name: Yang, Haitao
name: Hu, Zhijian
name: Xu, Nengluan
name: Xie, Baosong
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Hematology

description: Supplementary Material 1
Clinical genomic profiling to identify actionable alterations for very early relapsed triple-negative breast cancer patients in the Chinese population
Creators: name: Wang, Liye
name: Zhai, Qinglian
name: Lu, Qianyi
name: Lee, Kaping
name: Zheng, Qiufan
name: Hong, Ruoxi
name: Wang, Shusen
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Triple-negative breast cancer (TNBC) represents about 19% of all breast cancer cases in the Chinese population. Lack of targeted therapy contributes to the poorer outcomes compared with other breast cancer subtypes. Comprehensive genomic profiling helps to explore the clinically relevant genomic alterations (CRGAs) and potential therapeutic targets in very-early-relapsed TNBC patients. Formalin-fixed paraffin-embedded (FFPE) tumour tissue specimens from 23 patients with very-early-relapsed TNBC and 13 patients with disease-free survival (DFS) more than 36 months were tested by FoundationOne CDx (F1CDx) in 324 genes and select gene rearrangements, along with genomic signatures including microsatellite instability (MSI) and tumour mutational burden (TMB). In total, 137 CRGAs were detected in the 23 very-early-relapsed TNBC patients, averaging six alterations per sample. The mean TMB was 4 Muts/Mb, which was higher than that in non-recurrence patients, and is statistically significant. The top-ranked altered genes were TP53 (83%), PTEN (35%), RB1 (30%), PIK3CA (26%) and BRCA1 (22%). RB1 mutation carriers had shorter DFS. Notably, 100% of these patients had at least one CRGA, and 87% of patients had at least one actionable alteration. In pathway analysis, patients who carried a mutation in the cell cycle pathway were more likely to experience very early recurrence. Strikingly, we detected one patient with ERBB2 amplification and one patient with ERBB2 exon20 insertion, both of which were missed by immunohistochemistry (IHC). We also detected novel alterations of ROS1–EPHA7 fusion for the first time, which has not been reported in breast cancer before. The comprehensive genomic profiling can identify novel treatment targets and address the limited options in TNBC patients. Therefore, incorporating F1CDx into TNBC may shed light on novel therapeutic opportunities for these very-early-relapsed TNBC patients.
C: Bamboo Creek Sector South. Archaean basin margin geology and crustal evolution: an East Pilbara traverse
Creators: name: Nijman, Wouter
name: Kloppenburg, Armelle
name: Vries, Sjoukje T. De
Publisher: name: Geological Society of London
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary figure c: Bamboo Creek Sector South
Gravity and decoherence: the double slit experiment revisited
Creators: name: Samuel, Joseph
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The double slit experiment is iconic and widely used in classrooms to demonstrate the fundamental mystery of quantum physics. The puzzling feature is that the probability of an electron arriving at the detector when both slits are open is not the sum of the probabilities when the slits are open separately. The superposition principle of quantum mechanics tells us to add amplitudes rather than probabilities and this results in interference. This experiment defies our classical intuition that the probabilities of exclusive events add. In understanding the emergence of the classical world from the quantum one, there have been suggestions by Feynman, Diosi and Penrose that gravity is responsible for suppressing interference. This idea has been pursued in many different forms ever since, predominantly within Newtonian approaches to gravity. In this paper, we propose and theoretically analyse two `gedanken' or thought experiments which lend strong support to the idea that gravity is responsible for decoherence. The first makes the point that thermal radiation can suppress interference. The second shows that in an accelerating frame, Unruh radiation plays the same role. Invoking the Einstein equivalence principle to relate acceleration to gravity, we support the view that gravity is responsible for decoherence.
description: revised version, 17 pages, 3 figures, appeared in Classical and Quantum Gravity
GPS list of observation sites. Archaean basin margin geology and crustal evolution: an East Pilbara traverse
Creators: name: Nijman, Wouter
name: Kloppenburg, Armelle
name: Vries, Sjoukje T. De
Publisher: name: Geological Society of London
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: GPS list of observation sites 1-22.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 1260
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: cartulaire
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1260, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1260, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Stimulated transitions in resonant atom Majorana mixing
Creators: name: Bernabeu, Jose
name: Segarra, Alejandro
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Massive neutrinos demand to ask whether they are Dirac or Majorana particles. Majorana neutrinos are an irrefutable proof of physics beyond the Standard Model. Neutrinoless double electron capture is not a process but a virtual $ΔL = 2$ mixing between a parent $^AZ$ atom and a daughter $^A(Z-2)$ excited atom with two electron holes. As a mixing between two neutral atoms and the observable signal in terms of emitted two-hole X-rays, the strategy, experimental signature and background are different from neutrinoless double beta decay. The mixing is resonantly enhanced for almost degeneracy and, under these conditions, there is no irreducible background from the standard two-neutrino channel. We reconstruct the natural time history of a nominally stable parent atom since its production either by nature or in the laboratory. After the time periods of atom oscillations and the decay of the short-lived daughter atom, at observable times the relevant "stationary" states are the mixed metastable long-lived state and the non-orthogonal short-lived excited state, as well as the ground state of the daughter atom. We find that they have a natural population inversion which is most appropriate for exploiting the bosonic nature of the observed atomic transitions radiation. Among different observables of the atom Majorana mixing, we include the enhanced rate of stimulated X-ray emission from the long-lived metastable state by a high-intensity X-ray beam: a gain factor of 100 can be envisaged at current XFEL facilities. On the other hand, the historical population of the daughter atom ground state can be probed by exciting it with a current pulsed optical laser, showing the characteristic absorption lines: the whole population can be excited in a shorter time than typical pulse duration.
description: 17 pages, 4 figures
Blindness V Consciousness
Creators: name: Cheso, Diana
name: Zagefka, Hanna
name: Bjornsdottir, R. Thora
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Sociology
subject: FOS: Sociology
subject: Psychology
subject: FOS: Psychology
subject: Race and Ethnicity
subject: Social and Behavioral Sciences
subject: Gender and Sexuality

description: This study aims to investigate how blind and conscious ideologies are associated with the social group identities of transgender identity, race, and age.
MEGAPOOLS: VEGETATION DIEBACK AND RESTORATION POTENTIAL OF A DITCHED COASTAL SALT MARSH
Creators: name: Stahl, Katherine A.
Publisher: name: Digital Repository at the University of Maryland
Year: 2023
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Environmental science
subject: Coastal
subject: Marsh
subject: Megapool
subject: Restoration
subject: Runnel
subject: Wetlands

description: In many ditched coastal salt marshes, megapools, or large ponded areas of vegetation dieback,have formed. In combination with sea level rise, this interior marsh loss can decrease wildlife habitat suitability, resilience to storms, and other ecosystem services. However, mechanisms of megapool formation are poorly understood, hampering restoration efforts. Here, we explored differences in environmental characteristics between megapools in different stages of formation (Fully Formed, Partially Formed and Nonformed/Control) and between Elevations within megapools (High, Medium, Low). Using IRIS Films (Indicator of Reduction in Soil), we found that Fully Formed megapools had higher sulfide concentrations than Partially formed, which in turn were greater than Nonformed megapools. We additionally found that lower elevations correlated with higher sulfides, lower plant coverage, lower belowground biomass, lower Carbon Density, and predicted megapool type. We noted that in terms of elevation, vegetative cover, and biomass, Nonformed and Partially formed were more similar as were High and Medium elevations. Whereas in terms of soil characteristics, Fully Formed and Partially formed were more similar as were Medium and Low Elevations. To combat megapools and dieback, we will assess the effectiveness of two restoration techniques, the first of which is assessing the survival and growth of plantings at different spacings, elevations, and megapool formation levels. We found survival and growth was higher in Partially formed megapools than Fully formed, and no impact by spacing or elevation. Our second restoration technique is runnels, or 15” channels that reconnect megapools to ditches, which were installed in January of 2023. The data collected above will act as baseline data, repeated again. These baseline results support a close relationship between pool stages of formation, carbon storage, elevation, vegetation health, biomass production, and sulfide levels (Graphical Abstract).
Genome3D: integrating a collaborative data pipeline to expand the depth and breadth of consensus protein structure annotation.
Creators: name: Sillitoe, Ian
name: Andreeva, Antonina
name: Blundell, Tom L
name: Buchan, Daniel WA
name: Finn, Robert D
name: Gough, Julian
name: Jones, David
name: Kelley, Lawrence A
name: Paysan-Lafosse, Typhaine
name: Lam, Su Datt
name: Murzin, Alexey G
name: Pandurangan, Arun Prasad
name: Salazar, Gustavo A
name: Skwark, Marcin J
name: Sternberg, Michael JE
name: Velankar, Sameer
name: Orengo, Christine
Publisher: name: The Francis Crick Institute
Year: 2020
Subjects: Genetics & Genomics
Structural Biology & Biophysics
Computational & Systems Biology

description: Genome3D (https://www.genome3d.eu) is a freely available resource that provides consensus structural annotations for representative protein sequences taken from a selection of model organisms. Since the last NAR update in 2015, the method of data submission has been overhauled, with annotations now being 'pushed' to the database via an API. As a result, contributing groups are now able to manage their own structural annotations, making the resource more flexible and maintainable. The new submission protocol brings a number of additional benefits including: providing instant validation of data and avoiding the requirement to synchronise releases between resources. It also makes it possible to implement the submission of these structural annotations as an automated part of existing internal workflows. In turn, these improvements facilitate Genome3D being opened up to new prediction algorithms and groups. For the latest release of Genome3D (v2.1), the underlying dataset of sequences used as prediction targets has been updated using the latest reference proteomes available in UniProtKB. A number of new reference proteomes have also been added of particular interest to the wider scientific community: cow, pig, wheat and mycobacterium tuberculosis. These additions, along with improvements to the underlying predictions from contributing resources, has ensured that the number of annotations in Genome3D has nearly doubled since the last NAR update article. The new API has also been used to facilitate the dissemination of Genome3D data into InterPro, thereby widening the visibility of both the annotation data and annotation algorithms.
Optimal Secure Multi-Layer IoT Network Design
Creators: name: Chen, Juntao
name: Touati, Corinne
name: Zhu, Quanyan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Science and Game Theory (cs.GT)
subject: Cryptography and Security (cs.CR)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: With the remarkable growth of the Internet and communication technologies over the past few decades, Internet of Things (IoTs) is enabling the ubiquitous connectivity of heterogeneous physical devices with software, sensors, and actuators. IoT networks are naturally two-layer with the cloud and cellular networks coexisting with the underlaid device-to-device (D2D) communications. The connectivity of IoTs plays an important role in information dissemination for mission-critical and civilian applications. However, IoT communication networks are vulnerable to cyber attacks including the denial-of-service (DoS) and jamming attacks, resulting in link removals in IoT network. In this work, we develop a heterogeneous IoT network design framework in which a network designer can add links to provide additional communication paths between two nodes or secure links against attacks by investing resources. By anticipating the strategic cyber attacks, we characterize the optimal design of secure IoT network by first providing a lower bound on the number of links a secure network requires for a given budget of protected links, and then developing a method to construct networks that satisfy the heterogeneous network design specifications. Therefore, each layer of the designed heterogeneous IoT network is resistant to a predefined level of malicious attacks with minimum resources. Finally, we provide case studies on the Internet of Battlefield Things (IoBT) to corroborate and illustrate our obtained results.
description: 12 pages, to appear in IEEE Transactions on Control of Network Systems
title: История России: проблемные моменты (1917–2021 гг.)
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2024

description: Хрестоматия дополняет учебное пособие по истории России (1917–2021 гг.) и посвящена проблемным моментам отечественной истории XX в., одного из наиболее противоречивых и неоднозначно трактуемых в современной исторической науке и публицистике периодов. Издание составлено по хронологическо-тематическому принципу, включает пять ключевых тем: природа советской власти и политика большевиков 1917–1929 гг., трагические события индустриализации и коллективизации 1925–1941 гг., Великая Отечественная война 1941–1945 гг., массовые репрессии и, наконец, противоречия современной российской цивилизации. Издание подготовлено в соответствии с Федеральным государственным образовательным стандартом высшего образования. Хрестоматия предназначена для студентов всех специальностей и направлений подготовки, учебными планами которых предусмотрено изучение дисциплины «История России», а также будет полезна всем читателям, интересующимся отечественной историей.