cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Performance Evaluation of Advanced Deep Learning Architectures for Offline Handwritten Character Recognition
Creators: name: Soomro, Moazam
name: Farooq, Muhammad Ali
name: Raza, Rana Hammad
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: This paper presents a hand-written character recognition comparison and performance evaluation for robust and precise classification of different hand-written characters. The system utilizes advanced multilayer deep neural network by collecting features from raw pixel values. The hidden layers stack deep hierarchies of non-linear features since learning complex features from conventional neural networks is very challenging. Two state of the art deep learning architectures were used which includes Caffe AlexNet and GoogleNet models in NVIDIA DIGITS.The frameworks were trained and tested on two different datasets for incorporating diversity and complexity. One of them is the publicly available dataset i.e. Chars74K comprising of 7705 characters and has upper and lowercase English alphabets, along with numerical digits. While the other dataset created locally consists of 4320 characters. The local dataset consists of 62 classes and was created by 40 subjects. It also consists upper and lowercase English alphabets, along with numerical digits. The overall dataset is divided in the ratio of 80% for training and 20% for testing phase. The time required for training phase is approximately 90 minutes. For validation part, the results obtained were compared with the groundtruth. The accuracy level achieved with AlexNet was 77.77% and 88.89% with Google Net. The higher accuracy level of GoogleNet is due to its unique combination of inception modules, each including pooling, convolutions at various scales and concatenation procedures.
description: FIT 2017 Paper Published in IEEE FIT 2017
Clustering Diffused-Particle Method for Scattering from Large Ensembles of Electromagnetically Polarizable Particles
Creators: name: Wang, Lang
name: Rasskazov, Ilia L.
name: Carney, P. Scott
Publisher: name: arXiv
Year: 2020
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The Foldy-Lax equation is generalized for a medium which consists of particles with both electric and magnetic responses. The result is used to compute fields scattered from ensembles of particles. The computational complexity is reduced by hierarchical clustering techniques to enable simulations with on the order of 10^10 particles. With so many particles we are able to see the transition to bulk media behavior of the fields. For non-magnetic materials, the observable index, permittivity, and permeability of the effective bulk medium are in good agreement with the Clausius-Mossotti relation. The fields simulated for particles with both electric and magnetic responses are in good agreement with new analytical results for a generalized effective medium theory.
Biblische Betrachtungen zu den Chagall-Mittelfenstern in der Mainzer Stephanskirche
Creators: name: Groß, Rebekka
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Marc Chagall gehört zu den bekanntesten jüdischen Künstlern des 20. Jahrhunderts und ist berühmt für seine oft farbenfrohen Kunstwerke, die häufig biblische Inhalte thematisieren. Dabei nutzte er verschiedenste Medien: Neben seinen farbigen Gemälden in Öl, Wasserfarbe und Gouache schuf er auch Radierungen und Lithographien und gestaltete Keramiken, Mosaiken und Glasfenster, die meisten davon in Kirchen, einige aber auch in anderen öffentlichen Gebäuden.2 Die Fenster in der Mainzer Stephanskirche sind das einzige Werk, das Chagall für eine deutsche Kirche schuf. Gleichzeitig eines seiner letzten Werke, bilden sie den Abschluss seiner biblischen Botschaft und stellen ein machtvolles Zeichen der Versöhnung dar.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 02-03 (2019): Kultur berührt Religion. Beispiele aus Judentum und Christentum
In silico screening of FDA approved drugs on AXL kinase and validation for breast cancer cell line
Creators: name: Lavanya Nagamalla
name: J V Shanmukha Kumar
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: AXL kinase has been over expressed in many tumors and its involvement in cell proliferation, migration, survival, and resistance makes the kinase as attractive therapeutic target for many cancers. In this study, we performed a virtual screening of the food and drug administration (FDA) approved drug molecule database against AXL kinase for repurposing studies of breast cancer. We have identified three non-cancer drugs with good binding energies were subjected to in vitro breast cancer MCF-7 cell lines. Three drug molecules showing the activity with good IC50 values towards the cancer cell line. We also carried out a 2 dimensional (2D) quantitative structure activity relation (QSAR) studies on N-[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides derivatives to design potent inhibitors for AXL kinase. The final QSAR equation was robust with good predictivity and the statistical validation having R2 and Q2 values are 0.91 and 0.86, respectively. QSAR equation descriptors informs about the chemical properties of AXL inhibitors and helpful for designing novel inhibitors.
Formation of sunflower production efficiency in the agricultural enterprises
Creators: name: Natalya, Kondratyuk
name: Natalya, Kondratyuk
Publisher: name: Unknown
Year: 2015
Subjects: subject: Agribusiness
subject: Production Economics
subject: production efficiency
subject: sunflower
subject: production concentration
subject: intensity
subject: ecological production

description: The concept of sunflower production efficiency is specified and the indices system of its evaluation at the agricultural enterprises is generalized. The main tendencies of sunflower production in domestic agriculture and in agricultural enterprises activity of the oblast` are revealed. The conceptual principles of sunflower production efficiency increase at the agricultural enterprises with ecological standards adherence on the basis of ecological coefficient which takes into consideration the factors of the area under crop and the level of soil fertility renovation are proved. The method of determining this factor was approved as an example of specific farms. Dependence of sunflower production efficiency on the level of production concentration is investigated. The methodological approaches to efficiency evaluation of the certain expenses elements.
Functional study of acetaldehyde dehydrogenase 1 (ALDH1) in keratinocytes: Microarray integrating bioinformatics approaches
Creators: name: Shang-Jun Yin
name: Min-Woo Park
name: Bit-Na Lee
name: Yang, Jun-Mo
name: Yong-Doo Park
name: Qian, Guo-Ying
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 60506 Virology
subject: Computational Biology

description: The function of acetaldehyde dehydrogenase 1 (ALDH1) has been gradually elucidated in several diseases, especially in various cancers. However, the role of ALDH1 in skin-related diseases has been mostly unknown. Previously, we found that ALDH1 is involved in the pathogenesis of atopic dermatitis (AD). In this study, we used high-throughput screening (HTS) approaches to identify critical factors associated with ALDH1 in human keratinocytes to reveal its functions in skin. We overexpressed ALDH1 in human HaCaT keratinocytes and then conducted serial HTS studies, a DNA microarray and antibody array integrated with bioinformatics algorithms. Together, those tests identified several novel genes associated with the function of ALDH1 in keratinocytes, as well as AD, including CTSG and CCL11. In particular, GNB3, GHSR, TAS2R9, FFAR1, TAS2R16, CCL21, GPR32, NPFFR1, GPR15, FBXW12, CCL19, EDNRA, FFAR3, and RXFP3 proteins were consistently detected as hub proteins in the PPI maps. By integrating the datasets obtained from these HTS studies and using the strengths of each method, we obtained new insights into the functional role of ALDH1 in skin keratinocytes. The approach used here could contribute to the clinical understanding of ALDH1-associated applications for the treatment of AD.
Повышение эффективности управления конкурентоспособностью инновационной компании
Improving the efficiency of competitiveness innovative companies
Creators: name: Yuriy, Drachuk
name: Nataliya, Trushkina
name: Yuriy, Drachuk
name: Nataliya, Trushkina
Publisher: name: Unknown
Year: 2015
Subjects: subject: Financial Economics
subject: Production Economics
subject: innovative company
subject: competitiveness
subject: governance
subject: improving the efficiency of information system

description: The purpose of the article is to develop proposals to improve the competitiveness management innovation company. The essence of the concept is defined: the competitiveness of innovative companies; management system of innovative companies; production-manufacturing, investment and recruiting companies’ competitiveness. The main factors that hinder innovation activity of enterprises and hamper innovation are revealed. The major indicator of innovative activity in Ukraine is analyzed. Levels reached production-industrial, investment and recruitment company’s competitiveness are calculated. Evaluation of comprehensive competitiveness of innovative companies made. Proposals to improve the efficiency of management of competitiveness of innovative companies are developed through the introduction of an information system CRM. Economic and social efficiency of the implementation of CRM information is justified.
Kein Gespräch, nirgends. Martin Bubers Erzählung: Die Mutter
Creators: name: Boothe, Brigitte
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: »Eine Geschichte… soll man so erzählen, dass sie selber Hilfe sei.« (Martin Buber) Martin Bubers Erzählung Die Mutter ist die Geschichte des Verlustes von Heimat, Sprache und Beziehung. Es kommt zur Substitution der auf immer zerstörten Kindheitsheimat. Eine Schlüsselszene schildert in lakonischer Bündigkeit, wie das Kind überwältigt wird von der Gewissheit, die Mutter auf immer verloren zu haben. Das weitere Leben des Kindes und Jugendlichen steht im dunklen Bann dieses Schicksalsspruchs. Sodann gestaltet die Erzählung eine Transformation. Was im menschlichen Leben Begegnung heißt, wurde im Ich als tief verändernde Erfahrung wirksam. Es geht nicht mehr um die private Person Martin Buber; vielmehr schafft die transformative Bewegung einen menschheitlichen Bezug. Die Herausforderungen des Umgangs mit Verlust und Neuorientierung werden gemeistert durch Verwandlung des radikalen Mangels in geistige Fülle. Das Leben als Schauplatz Leben ist Biologie, und Leben ist biografische Existenz. Man fristet Lebenszeit, und man führt ein Leben. Menschliche Individuen bedienen sich eines sprachlichen Informationssystems, und sie erschaffen sich selbst im Medium der Sprache als Erzähler von Geschichten. Die Welt ist dem Erzählenden nicht alles, was der Fall ist, sondern das Gegebene verwandelt sich zum Schauplatz von Glück und Leid.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 02-03 (2019): Kultur berührt Religion. Beispiele aus Judentum und Christentum
title: Genetic Factors Associated with Anti-Factor H Autoantibodies in Atypical Hemolytic Uremic Syndrome (aHUS)
Creators: name: Valoti, Elisabetta
Publisher: name: The Open University
Year: 2018

description: Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy characterized by renal failure and determined by genetic and acquired defects of alternative pathway (AP) of the complement system. Autoantibodies against factor H (anti-FHs), a regulator of the AP, were reported in 10% of patients, and are associated with the deficiency of factor H related 1 (FHR1), a FH homologous protein.

 The aim of this thesis was to evaluate the contribution of genetics to the development of anti-FHs in aHUS.

 Thirty patients affected by aHUS resulted positive for anti-FHs (9.8%) and FHR1 deficiency was present in 83.3% of them. A healthy control also showed anti-FHs in concomitance with FHR1 deficiency documenting that the lack of FHR1 strongly predisposed to anti-FH development also in healthy subjects although this condition was not sufficient for the disease manifestation.

 The presence of infectious prodromal signs and an age at the disease onset around 8 years indicated that common infections may trigger the development of autoantibodies in subjects with at risk genetic background.

 Likely pathogenetic variants in complement genes were observed in 37% of our patients with anti-FHs. At variance, common variants in complement genes did not seem to contribute to the disease, as documented by comparing patients with super controls, unaffected subjects carrying FHR1 deficiency.

 Finally, I report that the HLA-DRB1*11:04 allele could be a predisposing genetic variant for anti-FH associated aHUS. Further works will be necessary to confirm this finding and to explore the presence of other genetic susceptibility factors that, in combination with the HLA-DRB1*11:04 allele and the FHR1 deficiency, could increase the risk for anti-FHs.
Impressum | Heftbezug | Abonnement
Creators: name: Schriftleitung, Verantwortliche
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Sehr geehrte Leserin, sehr geehrter Leser, vielen Dank für Ihr Interesse an unserer Zeitschrift für christlich-jüdische Begegnung im Kontext (ZfBeg). Für weiterführende Infos siehe PDF-Datei.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
Binodoxys kumaonensis
Creators: name: Akhtar, Mir Samim
name: Dey, Debjani
name: Usmani, Mohd. Kamil
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Braconidae
Binodoxys
Binodoxys kumaonensis

description: 44. Binodoxys kumaonensis (Stary and Raychaudhuri)
 Trioxys (Binodoxys) kumaonensis Stary and Raychaudhuri, 1982: 297-304.
 Host. Greenidea kumaoni Chakrabarti & Raychaudhuri on Berberis sp. (Stary and Raychaudhuri 1982).
 Distribution. Himachal Pradesh (Stary and Raychaudhuri 1982).
description: Published as part of Akhtar, Mir Samim, Dey, Debjani & Usmani, Mohd. Kamil, 2011, A catalogue of aphid parasitoids (Hymenoptera: Braconidae: Aphidiinae) from India, pp. 1-31 in Insecta Mundi 2011 (151) on page 9, DOI: 10.5281/zenodo.4531563
Molecular dynamics simulations of human α-thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites
Creators: name: Troisi, Romualdo
name: Balasco, Nicole
name: Vitagliano, Luigi
name: Sica, Filomena
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Computational Biology

description: Human α-thrombin (thrombin) is a multifunctional enzyme that plays a pivotal role in the coagulation pathway. Thrombin activity can be effectively modulated by G-quadruplex-based oligonucleotide aptamers that specifically interact with the two positively charged regions (exosites I and II) on the protein surface. Although insightful atomic-level snapshots of the recognition between thrombin and aptamers have been recently achieved through crystallographic analyses, some dynamic aspects of this interaction have not been fully characterized. We here report molecular dynamics simulations of thrombin in different association states: ligand-free and binary/ternary complexes with the aptamers TBA (at exosite I) and HD22_27mer (at exosite II). The simulations carried out on the binary and ternary complexes formed by thrombin with these aptamers provide a dynamic view of the interactions that stabilize them in a crystal-free environment. Interestingly, the analysis of the dynamics of the exosites in different thrombin binding states clearly indicates that the HD22_27mer binding at the exosite II favours conformations of exosite I that are prone to the TBA binding. Similar effects are observed upon the binding of TBA to the exosite I. These observations provide an atomic-level picture of the exosite inter-communication in thrombin and explain the experimentally detected cooperativity of the TBA/HD22_27mer binding. Communicated by Ramaswamy H. Sarma
Ефективність біопрепаратів у системі біологічного землеробства на меліорованих землях Волинського Полісся
Efficiency of biological preparations in the biological agriculture on reclaimed lands of Volyn Poliss
Creators: name: Kateryna, Polischuk
name: Kateryna, Polischuk
Publisher: name: Unknown
Year: 2015
Subjects: subject: Agribusiness
subject: Production Economics
subject: profit
subject: profitability
subject: seed inoculation
subject: biogran
subject: mikrogumin
subject: rizogumin
subject: fertilize system
subject: nitrogen-fixing biological preparations
subject: productivity

description: The research results showed that the use of organic and mineral fertilizers in the grain – fodder crop rotation facilitates improving soil nutritive regime and increasing soil fertility by increasing the content of easy hydrolysable nitrogen, movable phosphorus and exchange potassium in sod – podzolic sandy loam gley soil. Presowing inoculation of maize, field pea and spring barley seeds using such inoculation preparations as rizogumin, mikrogumin and biogran gives a positive effect on soil nutritive regime. This allows to increase the content of nitrogen by 5–10 % and phosphorus – 9–16 %. It was experimentally proved the appropriateness of biogran inoculation preparation use in the biological fertilize system in the sod-podzolic soil of Volyn Polissya region, that allows to increase the productivity of green maize to 40–45 t/ha as well as the rizogumin use allows to increase the productivity of field pea in the organic-mineral system to – 37–40 t/ha. Economic assessment of inoculation preparations use in various fertilize systems while green maize, field pea and spring barley cultivation on sod-podzolic soil was made.
Second virial coefficients of light nuclear clusters and their chemical freeze-out in nuclear collisions
Creators: name: Bugaev, K. A.
name: Vitiuk, O. V.
name: Grinyuk, B. E.
name: Sagun, V. V.
name: Yakovenko, N. S.
name: Ivanytskyi, O. I.
name: Zinovjev, G. M.
name: Blaschke, D. B.
name: Nikonov, E. G.
name: Bravina, L. V.
name: Zabrodin, E. E.
name: Kabana, S.
name: Kuleshov, S. V.
name: Farrar, G. R.
name: Zherebtsova, E. S.
name: Taranenko, A. V.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Here we develop a new strategy to analyze the chemical freeze-out of light (anti)nuclei produced in high energy collisions of heavy atomic nuclei within an advanced version of the hadron resonance gas model. It is based on two different, but complementary approaches to model the hard-core repulsion between the light nuclei and hadrons. The first approach is based on an approximate treatment of the equivalent hard-core radius of a roomy nuclear cluster and pions, while the second approach is rigorously derived here using a self-consistent treatment of classical excluded volumes of light (anti)nuclei and hadrons. By construction, in a hadronic medium dominated by pions, both approaches should give the same results. Employing this strategy to the analysis of hadronic and light (anti)nuclei multiplicities measured by ALICE at $\sqrt{s_{NN}} =2.76$ TeV and by STAR at $\sqrt{s_{NN}} =200$ GeV, we got rid of the existing ambiguity in the description of light (anti)nuclei data and determined the chemical freeze-out parameters of nuclei with high accuracy and confidence. At ALICE energy the nuclei are frozen prior to the hadrons at the temperature $T = 175.1^{+2.3}_{-3.9}$ MeV, while at STAR energy there is a single freeze-out of hadrons and nuclei at the temperature $T = 167.2 \pm 3.9$ MeV. We argue that the found chemical freeze-out volumes of nuclei can be considered as the volumes of quark-gluon bags that produce the nuclei at the moment of hadronization.
description: 15 pages, 4 figures, 3 tables
Additional file 3 of The association between psychological characteristics and physical activity levels in people with knee osteoarthritis: a cross-sectional analysis
Creators: name: Uritani, Daisuke
name: Kasza, Jessica
name: Campbell, Penny K.
name: Metcalf, Ben
name: Thorlene Egerton
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 3. Results of multiple regression analyses
Guaranteed convergence for a class of coupled-cluster methods based on Arponen's extended theory
Creators: name: Kvaal, Simen
name: Laestadius, Andre
name: Bodenstein, Tilmann
Publisher: name: arXiv
Year: 2020
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Numerical Analysis (math.NA)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: A wide class of coupled-cluster methods is introduced, based on Arponen's extended coupled-cluster theory. This class of methods is formulated in terms of a coordinate transformation of the cluster operators. The mathematical framework for the error analysis of coupled-cluster methods based on Arponen's bivariational principle is presented, in which the concept of local strong monotonicity of the flipped gradient of the energy is central. A general mathematical result is presented, describing sufficient conditions for coordinate transformations to preserve the local strong monotonicity. The result is applied to the presented class of methods, which include the standard and quadratic coupled-cluster methods, and also Arponen's canonical version of extended coupled-cluster theory. Some numerical experiments are presented, and the use of canonical coordinates for diagnostics is discussed.
description: 11 pages
Brownian intersections, cover times and thick points via trees
Creators: name: Peres, Yuval
Publisher: name: arXiv
Year: 2003
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60J15

description: There is a close connection between intersections of Brownian motion paths and percolation on trees. Recently, ideas from probability on trees were an important component of the multifractal analysis of Brownian occupation measure, in joint work with A. Dembo, J. Rosen and O. Zeitouni. As a consequence, we proved two conjectures about simple random walk in two dimensions: The first, due to Erdős and Taylor (1960), involves the number of visits to the most visited lattice site in the first $n$ steps of the walk. The second, due to Aldous (1989), concerns the number of steps it takes a simple random walk to cover all points of the $n$ by $n$ lattice torus. The goal of the lecture is to relate how methods from probability on trees can be applied to random walks and Brownian motion in Euclidean space.
Rezension zu: Werner, Hans-Joachim; Silvera David; Flashman, Alan (2020): Verbundenheit im Gegenüber. Martin Buber und der Umgang mit Konflikten, Bodenburg: Edition AV, 210 Seiten.
Creators: name: Ralla, Mechthild
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Als »ein in tiefer Zwiefalt wirr verschlungenes Geschehen « charakterisiert Martin Buber das Verhältnis der Grundworte genannten »Ich-Du« und »Ich-Es« (S. 8), und dieses Geschehen habe einen bestimmbaren Anfang: »Der Ursprung alles Konflikts zwischen mir und meinen Mitmenschen ist, dass ich nicht sage, was ich meine und dass ich nicht tue, was ich sage« (S. 48). Der Buber-Experte Hans-Joachim Werner widmet sich in diesem grundlegenden Beitrag den Gedanken Bubers als Denker des Dialogs über den Umgang mit Konflikten (S. 46). Werner beschreibt die aus einem Mangel an Authentizität folgenden Spannungen auf Bubers von persönlichen und politischen Konflikten geprägten Leben. Die aus diesen Erfahrungen heraus entwickelten Vorschläge Bubers zur Lösung von Konflikten sind übersichtlich und ausführlich zusammengestellt und im systematischen wie auch philosophiegeschichtlichen Kontext verstehbar gemacht. Bubers Vorschläge haben einen gemeinsamen Leitfaden für die Lösung: bei sich beginnen, aber nicht bei sich enden. Für die Lösung selbst gibt Buber drei Schritte vor: 1. Selbsterhellung (Selbstbesinnung), 2. Selbstbeharrung (ich bin, bleibe Teil des Konflikts) und 3. Sühne (Wiedergutmachung). Wie dies im Einzelnen gelingen kann, mit welchen Barrieren zu rechnen und wie diese zu überwinden sind, zeigen Werners Ausführungen.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
BILINGUALISM HELPS TO IMPROVE CHILDREN'S COGNITIVE DEVELOPMENT
Creators: name: Tilavova, Madinabonu Chori qizi
Publisher: name: Zenodo
Year: 2025

description: The article is devoted to the importance of bilingualism in learning a foreign language. There is a significant influence of bilingualism on the development of children’s cognitive skills and abilities. In addition, it is mentioned that bilingualism helps one to increase his critical and creative thinking which may aid a learner to learn a language effectively and easily. There are given some examples of how bilingualism can have a positive effect on language improvement and children education. Bilingualism plays a significant role in enhancing children's cognitive development. Research shows that children who are exposed to two or more languages at an early age develop superior cognitive abilities compared to their monolingual peers. Bilingual children often exhibit improved executive functions, such as problem-solving, attention control, and task-switching. The process of switching between languages strengthens the brain’s cognitive flexibility, fostering better memory retention and multitasking skills. Moreover, bilingualism enhances metalinguistic awareness, which helps children understand the structure of language more profoundly. This ability to think in multiple languages not only contributes to better academic performance but also helps children develop stronger social skills. Despite the challenges bilingual children might face in terms of language acquisition, the long-term cognitive benefits outweigh the initial difficulties, making bilingualism a valuable asset in their cognitive and academic growth.
Amygdalin as multi-target anticancer drug against targets of cell division cycle: double docking and molecular dynamics simulation
Creators: name: Khattab Al-Khafaji
name: Tugba Taskin Tok
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Cell-division protein kinases (CDKs) are gorgeous examples of targets for the helpful treatment of cancer by using multi-target inhibitors. Specifically, targeting cell-division protein kinase1/cyclin B (CDK1/Cyclin B), cell-division protein kinase 2/cyclin A (CDK2/Cyclin A) and cell-division protein kinase 4/cyclin D1 (CDK4/Cyclin D1) are considered a safe strategy to over the toxicity complications which are emerging from low specificity. In this work, we conducted the double docking and molecular dynamics to explicate the effect of amygdalin upon conformational modifications of selected targets. Moreover, the principal component analysis (PCA) was employed to inspect the effect of amygdalin on the fundamental motions of the each protein as target. Docking results illustrated that the binding free energies of amygdalin (AMY) to CDK1/Cyclin B, CDK 2/Cyclin A and CDK 4/Cyclin D1 were to be −9.41, −9.02 and −10.6 kcal/mol, respectively. The PCA results disclosed that binding of the AMY minimized the fundamental dynamics of CDK1/Cyclin B and CDK2/Cyclin A. The obtained results can give an insight into inhibitory activity of amygdalin that could help in designing of potential inhibitors. In the other word, it can be used AMY to inhibit other mechanisms and/or hallmarks of cancer. Communicated by Ramaswamy H. Sarma
Observation of Flat Frequency Bands at Open Edges and Antiphase Boundary Seams in Topological Mechanical Metamaterials
Creators: name: Qian, Kai
name: Zhu, Linghua
name: Ahn, Keun Hyuk
name: Prodan, Camelia
Publisher: name: arXiv
Year: 2020
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Motivated by the recent theoretical studies on a two-dimensional (2D) chiral Hamiltonian based on the Su-Schrieffer-Heeger chains, we experimentally and computationally demonstrate that topological flat frequency bands can occur at open edges of 2D planar metamaterials and at antiphase boundary seams of ring-shaped or tubular metamaterials. Specifically, using mechanical systems made of magnetically coupled spinners, we reveal that the presence of the edge or seam bands that are flat in the entire projected reciprocal space follows the predictions based on topological winding numbers. The edge-to-edge distance sensitively controls the flatness of the edge bands and the localization of excitations. The analogue of the fractional charge state is also observed. Possible realizations of flat bands in a large class of metamaterials, including photonic crystals and electronic metamaterials, are discussed.
Molecular dynamics simulations of human α-thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites
Creators: name: Troisi, Romualdo
name: Balasco, Nicole
name: Vitagliano, Luigi
name: Sica, Filomena
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Computational Biology

description: Human α-thrombin (thrombin) is a multifunctional enzyme that plays a pivotal role in the coagulation pathway. Thrombin activity can be effectively modulated by G-quadruplex-based oligonucleotide aptamers that specifically interact with the two positively charged regions (exosite I and II) on the protein surface. Although insightful atomic-level snapshots of the recognition between thrombin and aptamers have been recently achieved through crystallographic analyses, some dynamic aspects of this interaction have not been fully characterized. We here report molecular dynamics simulations of thrombin in different association states: ligand-free and binary/ternary complexes with the aptamers TBA (exosite I) and HD22_27mer (exosite II). The simulations carried out on the binary and ternary complexes formed by thrombin with these aptamers provide a dynamic view of the interactions that stabilize them in a crystal-free environment. Interestingly, the analysis of the dynamics of the exosites in different thrombin binding states clearly indicates that the HD22_27mer binding at the exosite II favours conformations of exosite I that are prone to the TBA binding. Similar effects are observed upon the binding of TBA to the exosite I. These observations provide an atomic-level picture of the exosite inter-communication in thrombin and explain the experimentally detected cooperativity of the TBA/HD22_27mer binding.
Нестабильность производства продукции растениеводства в Гагаузии как объективный экономический процесс в сельском хозяйстве
Instability of production of goods of plant-grower in Gagauzia as objective economic process in agriculture
Creators: name: Ljudmila, Todorich
name: Ljudmila, Todorich
Publisher: name: Unknown
Year: 2015
Subjects: subject: Agribusiness
subject: Crop Production/Industries
subject: Production Economics
subject: agriculture
subject: Gagauzia
subject: stability
subject: yield
subject: gross yield

description: To the article the analysis of dynamics of production and stability of basic agricultural cultures of Gagauzia is driven. It is well-proven that modern operating of the agricultural enterprises specialized on the production of goods of plant-grower conditions are characterized enhanceable dynamic quality of external and internal environment and, as a result – by the high level of instability, in this connection principal reasons of instability of production of goods of plant-grower mark and a row over of recommendations is brought on the improvement of situation. Taking into account the qualificatory value of efficiency of the use of earth in agriculture as a main mean of production, a study of the productivity of grain-crops is undertaken in Gagauzia for 1995–2014 and the level of their stability is educed. The most steady is educed for a production in the conditions of risk agriculture agricultural culture.
Additional file 2 of The association between psychological characteristics and physical activity levels in people with knee osteoarthritis: a cross-sectional analysis
Creators: name: Uritani, Daisuke
name: Kasza, Jessica
name: Campbell, Penny K.
name: Metcalf, Ben
name: Thorlene Egerton
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2. Scatter plots for number of steps per day and psychological characteristics
Resettlement as development? Understanding the impacts of resttlement and rehabilitation in the Mumbai urban transport project (MUTP), India
Creators: name: Takeuchi, Ko
Publisher: name: University of British Columbia
Year: 2011

description: Displacement induced by urban development projects, is becoming an increasingly significant issue in rapidly growing cities with high proportions of 'informal settlements' or 'slums'. In the case of Mumbai, India, the Mumbai Urban Transport Project (MUTP), financed by the World Bank in 2002, included a Resettlement and Rehabilitation component with a Resettlement and Rehabilitation Policy, embracing the World Bank's Involuntary Resettlement Policy, to help restore the overall living standards of the displaced households. This paper, based on 48 face-to-face interviews with the displaced families, assesses the impact of this resettlement, by adopting the concepts and theories of "household assets" as developed by the discourse on international development. The evidence indicating decreased household assets raises questions about the World Bank's perspective of resettlement as 'development'. This research shows that the essential endeavor for consideration in such relocation projects is not only the change in the physical environment from low-rise villages to medium-rise apartments, but also the way by which the resettlers organize themselves to manage and maintain their new form of housing. Hence, the paper suggests that resettlement projects must make a stronger commitment to allow resettlers to shift in consolidated groups, with special support for the group members to learn and to cooperate with one another to maintain their new housing. With respect to the World Bank's involuntary resettlement policy, this paper argues that the interaction between efforts to consult with the public and strategies to prevent unauthorized capture of project benefits must be closely examined. In fact, the policy may be partially applied to restrain the strategies of local agencies to prevent such capture, as the policy may not always be congruent with the intricate systems of slum settlements. The conclusion and final recommendation is for relocation analyses to be extended beyond basic housing standards, to also evaluate economic, social, and hygienic repercussions, and their influences on one another.
Binodoxys longispinus
Creators: name: Akhtar, Mir Samim
name: Dey, Debjani
name: Usmani, Mohd. Kamil
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Braconidae
Binodoxys
Binodoxys longispinus

description: 45. Binodoxys longispinus (Shuja-Uddin)
 Trioxys (Binodoxys) longispinus Shuja-Uddin, 1983: 36-38.
 Host. Aphis farinosa Gmelin on Salix caprea (Shuja-Uddin 1983).
 Distribution. Jammu and Kashmir (Shuja-Uddin 1983).
description: Published as part of Akhtar, Mir Samim, Dey, Debjani & Usmani, Mohd. Kamil, 2011, A catalogue of aphid parasitoids (Hymenoptera: Braconidae: Aphidiinae) from India, pp. 1-31 in Insecta Mundi 2011 (151) on page 9, DOI: 10.5281/zenodo.4531563
Rezension zu: Perel, Sally (1992/2016): Ich war Hitlerjunge Salomon, München: heyne fliegt, 255 Seiten.
Creators: name: Gasparevic, Vanesa
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Sally Perel ist ein in Peine bei Braunschweig geborener, jüdischer Autor. Mit seinen 95 Jahren leistet er heute einen wichtigen Beitrag zur Erinnerungskultur, da er seine Erfahrungen nicht nur in niedergeschriebener Form, sondern auch mit Schülerinnen und Schülern vor Ort teilt, um sich deren Gedanken, Fragen und vielleicht auch deren Unverständnis zu stellen. Denn Sally Perels Biografie Ich war Hitlerjunge Salomon unterscheidet sich von den Geschichten der meisten anderen Holocaust-Überlebenden: Er erzählt nicht von Konzentrationslagern oder seinen jüdischen Mitgefangenen, sondern von Josef (Jupp) Perjell, seiner neuen und falschen Identität, die ihn schützte und ihm das Überleben ermöglichte. Getarnt als Hitlerjunge erlebte Perel die Zeit des Nationalsozialismus unter den Feinden seiner Glaubensgenossen. Erst nach mehr als 40 Jahren überwand er sich, seine Geschichte niederzuschreiben, »denn im Lauf der Zeit begriff [er], dass das Trauma, das [er] zu verdrängen suchte, sich nicht länger verdrängen ließ« (S. 8). Perel erklärt im Vorwort, was ihn doch dazu bewegte, seine Geschichte preiszugeben und weshalb er sie so viele Jahre lang für sich behielt. Das Gefühl, sich nicht auf dieselbe Stufe mit den anderen Überlebenden stellen zu können, hinderte ihn daran seine Geschichte zu erzählen, denn während sie »an die Grenzen dessen gegangen [sind], was ein Mensch ertragen kann […].
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
The Influence of “Last One Kilometer” Service Quality on Customer Loyalty under C2C Mode——The Mediating Role of Customer Satisfaction
Creators: name: LI Daosheng
name: DING Xinxin
name: KE Jun
name: LI Daosheng
name: DING Xinxin
name: KE Jun
Publisher: name: Unknown
Year: 2017
Subjects: subject: Agribusiness
subject: Service quality, Client satisfaction, Client loyalty, Mediating role

description: Via questionnaire investigation on express users in Wuhan colleges and universities, it is found that client satisfaction plays partial mediator role between service quality of express industry and client loyalty. Moreover, correlation regression analysis of data is conducted by SPSS17.0 software. It is found that communication quality, order quality, delivery quality and remedy quality have significantly positive impacts on client satisfaction, while personalized service quality does not have significant impact on client satisfaction; communication quality, order quality, personalized service quality and remedy quality have significantly positive impacts on client loyalty, while communication quality does not have significant impact on client loyalty. Finally, countermeasures and suggestions are proposed according to the above conclusions.
Rezension zu: Berger, Joel (2019): Gesetz– Ritus – Brauch. Einblicke in jüdische Lebenswelten, Heidelberg: Universitätsverlag Winter, 446 Seiten.
Creators: name: Schwendemann, Wilhelm
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Der etwas spröde Buchtitel gibt nicht wieder, was den Lesenden erwartet. In 38 Kapiteln (nebst Vor- und Nachwort, Biografie von Joel Berger, Anmerkungen, Literatur, Register) gibt es eine profunde Einführung in den Lebensalltag von Juden und Jüdinnen, Reflexionen über Judentum in Südwestdeutschland nach der Schoah, über den christlich-jüdischen Dialog, Antisemitismus. Es werden überraschende Fragen gestellt, wie zum Beispiel: Was hat das Einhorn mit der Bibel zu tun (S. 286 – 291)? Das Judentum wird vom ehemaligen württembergischen Landesrabbiner in seiner Vielfalt als Pluralität von Lebensformen und Lebensvollzügen charakterisiert (S. 15), die sich aus der lebendigen Interpretation der Bibel, wie zum Beispiel den 613 Weisungen aus der Torah, und aus talmudischen Traditionen speist. Für Joel Berger ist zentral wichtig, Judentum als gelebten ethischen Monotheismus zu verstehen. Hier wäre seiner Meinung nach auch die Gemeinsamkeit mit dem Christentum und dem Islam zu suchen, auch wenn in Joel Bergers Ausführungen ebenso die Unterschiede deutlich benannt werden, manchmal humorvoll und augenzwinkernd: »Es gab eine Zeit, da die Jungfrau Maria noch nicht katholisch war« (S. 19). Sehr instruktiv ist die Vorstellung jüdischer Lebensweise als Bildungsunterfangen (vgl. Ps 119) (S. 28), was dann in die Darstellung jüdischer Gelehrsamkeit in Schulen, Hochschulen, Wissenschaft übergeht (S. 31– 53). Alltagsverhalten wie »vor einem grauen Haupt sollst du aufstehen…« (Lev 19,32) (S. 55) oder die Pflege des Hauses (S. 72 –76), die Pflege des eigenen Körpers (S. 77– 81), Bekleidung (S. 82 – 88),Tallit und Zizit (S. 89 – 93), Essen und Trinken (S. 94 –112) werden ausführlich erklärt und zum Teil mit vergnüglichen oder nachdenklichen Geschichten vermittelt.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
Rezension zu: Schnelle, Udo (2019): Die getrennten Wege von Römern, Juden und Christen. Religionspolitik im 1. Jahrhundert n. Chr., Tübingen: Mohr Siebeck, 212 Seiten.
Creators: name: Groß, Rebekka
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Der emeritierte Neutestamentler Udo Schnelle legt mit dieser Veröffentlichung einen kompakten Beitrag zu einer exegetisch hochaktuellen Debatte vor, die sich durchaus auch als Einführung eignet: nämlich die Diskussion um die Entstehung des Christentums aus dem Judentum. Ab wann kann vom Christentum als eigenständiger Religion gesprochen werden, und wie war sein Verhältnis zum Judentum? Besagte Debatte wird in der Forschung unter dem Titel Parting of the ways, Trennung der Wege, geführt; ein Titel, den Schnelle für missverständlich hält, denn seiner Meinung nach gab es gar keine Trennung, weil es gar keinen gemeinsamen Weg gegeben habe. Das Buch trägt deshalb auch passenderweise den Titel Die getrennten Wege von Römern, Juden und Christen. Schnelle möchte darin die Bedeutung der römischen Religionspolitik für die Entstehung des Christentums und sein Verhältnis zum Judentum hervorheben.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
Selective interactions in trapped ions: state reconstruction and quantum logic
Creators: name: Solano, E.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose the implementation of selective interactions of atom-motion subspaces in trapped ions. These interactions yield resonant exchange of population inside a selected subspace, leaving the others in a highly dispersive regime. Selectivity allows us to generate motional Fock (and other nonclassical) states with high purity out of a wide class of initial states, and becomes an unconventional cooling mechanism when the ground state is chosen. Individual population of number states can be distinctively measured, as well as the motional Wigner function. Furthermore, a protocol for implementing quantum logic through a suitable control of selective subspaces is presented.
description: 4 revtex4 pages and 2 eps figures. Submitted for publication
Measurement of Rural Inclusive Financial Development and Analysis of Spatial Effects on Anti-poverty
Creators: name: LU Yongbin
name: WANG Chunmei
name: QU Weican
name: LU Yongbin
name: WANG Chunmei
name: QU Weican
Publisher: name: Unknown
Year: 2017
Subjects: subject: Agribusiness
subject: Inclusive financial, Rural finance, Anti-Poverty, Spatial effect

description: Based on two dimensions of supply and demand, we use six indicators to establish a rural inclusive financial development index and evaluate the development of China's rural inclusive finance. We use spatial panel data model to examine the relationship between financial inclusion and rural poverty. Results show that: (i) both the rural inclusive finance and rural residents' per capita consumption present spatial clustering feature and show significant spatial correlation; (ii) the development of rural inclusive finance has significant spatial effect on poverty alleviation along time and space dimensions. In this study, the paper puts forward policy recommendations on strengthening the rural financial resources flow and constructing diversified rural inclusive financial system.
Das andere AD(H)S. Entwicklung von Lösungsansätzen zur Früherkennung von AD(H)S-Betroffenen ohne Hyperaktivität im Schulalltag
Creators: name: Bundi, Giannina
Publisher: name: Zenodo
Year: 2021
Subjects: Sonderpädagogik
ADHS
Früherkennung
Masterarbeit

description: Der Begriff AD(H)S wird häufig mit dem Bild des ‹Zappelphilipps› assoziiert. Dass damit aber auch das andere AD(H)S – die sogenannte hypoaktive Form – gemeint ist, ist vielen nicht bewusst. Auch des-halb werden AD(H)S-Betroffene ohne Hyperaktivität oft spät erkannt. Ziel dieser Arbeit ist es, Möglichkeiten zur Früherkennung von AD(H)S ohne Hyperaktivität im Schulalltag zu entwickeln. Um ein gesamtheitliches Bild zu erhalten, wurden Interviews mit drei Betroffenen und drei Fachpersonen geführt. Die Ergebnisse zeigen, wie unterschiedlich das Erscheinungsbild sein kann und wie schwierig es des-halb ist, typische Erkennungsmerkmale zu definieren. Aufgrund der gewonnenen Erkenntnisse wird ein möglicher Ansatz zur Früherkennung abgeleitet. Eine zentrale Erkenntnis ist, dass erst die Kombination von vorhandenem Wissen über AD(H)S sowie eine zielorientierte Beobachtung das Erkennen ermöglichen.