cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Copertura dei campi di un centro tennis nel comune di Neuchâtel (NE)
Creators: name: Darani, Tobia
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2019

description: Il tema prevede la realizzazione di una copertura in legno di due campi di un centro tennis nel comune di Neuchâtel (circa 479 s.l.m.). La struttura richiede un importante lavoro di approfondimento sulle varianti architettoniche vista la presenza di vincoli quali: altezze interne 3m ai bordi e 8m al centro, nessun pilastro interno, possibilità di continuazione struttura in futuro quindi sul lato di 37m nessun pilastro portante, nessuna parete divisoria internamente, altezza massima 11m (derogabile). La struttura in legno è di 37x 34m e copre la superficie di due campi da tennis con un’altezza massima di 11m, sul resto del mappale resteranno tre campi da tennis senza copertura.
Evaluating the Uptake and Impact of Clinical Decision Support Systems in an Australian Healthcare Setting
Creators: name: BONAKDEH, ERFAN SHAKIBAEI
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 420302
subject: Digital health

description: Recognised as the most aspiring usage of IT in healthcare in reducing medication errors and inefficiency, Clinical Decision Support System (CDSS) streamline medication prescription and administration processes and enabling the system to provide high quality services. Numerous studies have examined the impact of CDSS and showed that their positive effects on hospital outcomes are not as significant as anticipated. Therefore, the purpose of this study was to explore the factors influencing the perception of users and their attitude towards using the technology, as well as factors that contribute to usage behaviour.
Evaluation of Spectral Pretreatments, Spectral Range and Regression Methods for Quantitative Spectroscopic Analysis of Soil Organic Carbon Composition
Creators: name: Hongzhang Kang
name: Huanhuan Gao
name: Wenjuan Yu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Although there is an increasing interest in using infrared spectroscopy for the simple, rapid and inexpensive prediction of soil organic carbon content, few studies have used this technique to measure organic carbon chemistry. In this paper, based on both near-infrared and mid-infrared diffuse reflectance spectroscopy, we compared the use of instrumentation, spectral pretreatment and regression method for the prediction of three parameters related to organic carbon content, one related to isotopic composition and five related to organic carbon chemistry. A total of 140 soil samples collected from seven oriental oak forest sites across East China were used as the data set for the calibration-validation procedure. Calibrations using sample set partitioning based on joint x-y distances method significantly outperformed those using Kennard-Stone method. Compared to models using linear method (i.e., partial least squares), those using non-linear regression method (i.e., support vector machines) greatly improved the prediction precision of the alkyl-to-O-alkyl ratio and performed slightly better for the other organic carbon chemical compositions. Instrumentation had a large effect as mid-infrared models had higher average prediction accuracies than near-infrared models. We finally proposed a model using second derivative preprocessing, joint x-y distances based sample set partitioning, mid-infrared spectra and support vector machines regression to quantify organic carbon chemistry in this study. The results are helpful for the further study of soil composition measurement.
title: Vocabulario de terminos de arte
Creators: name: Adeline, Jules
name: Mélida, José Ramon. Traducteur
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: Bibliothèque patrimoniale Villon (Rouen), fonds Leber, m 2807 Fonds normand
On the Effect of Bias Estimation on Coverage Accuracy in Nonparametric Inference
Creators: name: Calonico, Sebastian
name: Cattaneo, Matias D.
name: Farrell, Max H.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Nonparametric methods play a central role in modern empirical work. While they provide inference procedures that are more robust to parametric misspecification bias, they may be quite sensitive to tuning parameter choices. We study the effects of bias correction on confidence interval coverage in the context of kernel density and local polynomial regression estimation, and prove that bias correction can be preferred to undersmoothing for minimizing coverage error and increasing robustness to tuning parameter choice. This is achieved using a novel, yet simple, Studentization, which leads to a new way of constructing kernel-based bias-corrected confidence intervals. In addition, for practical cases, we derive coverage error optimal bandwidths and discuss easy-to-implement bandwidth selectors. For interior points, we show that the MSE-optimal bandwidth for the original point estimator (before bias correction) delivers the fastest coverage error decay rate after bias correction when second-order (equivalent) kernels are employed, but is otherwise suboptimal because it is too “large”. Finally, for odd-degree local polynomial regression, we show that, as with point estimation, coverage error adapts to boundary points automatically when appropriate Studentization is used; however, the MSE-optimal bandwidth for the original point estimator is suboptimal. All the results are established using valid Edgeworth expansions and illustrated with simulated data. Our findings have important consequences for empirical work as they indicate that bias-corrected confidence intervals, coupled with appropriate standard errors, have smaller coverage error and are less sensitive to tuning parameter choices in practically relevant cases where additional smoothness is available.
Andiamo al museo? – Elementi teorici e proposte didattiche per favorire l’avvicinamento degli allievi del primo ciclo di scuola elementare al museo
Creators: name: Blaschitz, Anita
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2019

description: Lo scopo del lavoro svolto è stato quello di indagare come sia possibile favorire l’avvicinamento dei bambini del primo ciclo di scuola elementare al museo. In particolare ho cercato di ricercare alcune buone pratiche che un docente può mettere in atto, come ci si può preparare per svolgere questa esperienza e quali potenzialità possono scaturire dal contatto con una struttura museale, evidenziando i benefici che questo avvicinamento può portare. Gli approfondimenti teorici fatti, la visita ad una mostra al museo LAC di Lugano e le sperimentazioni pratiche, mi hanno permesso di evidenziare una serie di elementi. In primo luogo il museo offre la possibilità di fare nuove esperienze che coinvolgono tutti i sensi, aiuta ad ampliare i programmi scolastici, incrementando e sostenendo il processo di apprendimento degli allievi. Secondariamente avvicina i bambini al patrimonio culturale e soprattutto permette loro di entrare in contatto con oggetti originali, che possono favorire lo sviluppo di un atteggiamento critico e riflessivo. Come docenti, grazie ad un’adeguata preparazione personale e a una progettazione didattica mirata in relazione al contesto e all’età degli allievi, possiamo quindi favorire l’importante rapporto scuola-museo, aiutando i bambini a scoprire e conoscere questa struttura. La formazione degli alunni e la loro crescita personale non potranno che essere arricchite grazie al contatto con una struttura museale.
Motivation in pediatric motor rehabilitation: A systematic search of the literature using the self-determination theory as a conceptual framework
Creators: name: Meyns, Pieter
name: Mettelinge, Tine Roman De
name: Spank, Judith Van Der
name: Coussens, Marieke
name: Waelvelde, Hilde Van
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Computational Biology

description: Objective: Motivation is suggested as an important factor in pediatric motor rehabilitation. Therefore, we reviewed the existing evidence of (motivational) motor rehabilitation paradigms, and how motivation influences rehabilitation outcome using self-determination theory as conceptual framework. Methods: PubMed and Web-of-Science databases were systematically searched until June 2015. Data were independently extracted and critiqued for quality by three authors. Studies reporting motivational aspects were included. Most studies examined new technology (e.g., virtual reality [VR]). Results: Out of 479 records, three RCT, six case-control, and six non-comparative studies were included with mixed quality. Motivation was rarely reported. Training individualization to the child’s capabilities with more variety seemed promising to increase motivation. Motivation increased when the exercises seemed helpful for daily activities. Conclusions: Motivation in pediatric rehabilitation should be comprehensively assessed within a theoretical framework as there are indications that motivated children have better rehabilitation outcomes, depending on the aspect of motivation.
Transdiagnostic and Cross-Cultural Perspectives of Paediatric Attention-Deficit/Hyperactivity Disorder
Creators: name: CHAU, TRACEY
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 520301
subject: Clinical neuropsychology
classificationCode: 450416
subject: Aboriginal and Torres Strait Islander psychology

description: Attention-deficit/hyperactivity disorder (ADHD) is the most prevalent neurodevelopmental condition worldwide. Despite this, there remain numerous environmental and personal barriers precluding many families from accessing suitable diagnostic and interventional services. This thesis explored the strengths and limitations of commonly used screening measures for ADHD and emotional and behavioural wellbeing in neurodivergent children and Aboriginal and Torres Strait Islander children. The findings highlight the need for assessment tools that can adequately identify and assist in differentiating between subclinical autistic and ADHD traits in neurodivergent children, and capture psychological constructs consistent with Aboriginal and Torres Strait Islander conceptualisations of emotional and behavioural wellbeing.
title: Spatial fragmentation as an opportunity for resilience building through urban acupuncture: Learning from Tehran and Bucharest
Creators: name: Naghibi, Maryam
name: Forgaci, Claudiu
name: Faizi, Mohsen
Publisher: name: Conference Proceedings XXIX International Seminar on Urban Form ISUF 2022 Urban Redevelopment and Revitalisation A Multidisciplinary Perspective/Lodz University of Technology Press
Year: 2023
Subjects: Spatial fragmentation, Leftover space, Resilience, Urban acupuncture.

description: The rapid urbanization of metropolitan environments worldwide has led to increasing spatial fragmentation. Disconnected spaces have revealed spatial and social voids that reduce the adaptive capacity of a region. However, these spaces also offer latent potential for urban resilience. Accordingly, this study reveals how urban acupuncture promotes resilience in leftover spaces to reduce or embrace spatial fragmentation. This paper reviews spatial fragmentation and urban resilience from descriptive-analytical and normative perspectives. It proposes urban acupuncture to locate critical spatial structures and processes on a small scale. The study develops a conceptual framework around fragmentation and urban acupuncture. It investigates the assumptions behind the concepts of spatial fragmentation and proposes a dialectical framing of vacancy based on resilience and urban acupuncture, along with a reassessment of leftover space as a planning tool. The framework’s application is demonstrated in Tehran and Bucharest. As a result, spatial fragmentation significantly influences urban resilience to prevent expansion. Urban acupuncture opens the possibility of developing optimistic scenarios by considering leftover spaces and the broader opportunities they generate for urban resilience. Depending on the urban context, this strategy can be applied through a single intervention in a specific place or a network of coordinated interventions in different locations.
title: OFROM: interview avec ilcf22a06
Creators: name: Delafontaine, François
name: Johnsen, Laure-Anne
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.cbf4cm06.v2#6b6abc2aaada5c4c682d832f2e926c720c7034bf
title: 03_0471
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
title: 03_0143
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Measuring glitch recoveries and braking indices with Bayesian model selection
Creators: name: Liu, Yang
name: Keith, Michael J.
name: Antonopoulou, Danai
name: Weltevrede, Patrick
name: Shaw, Benjamin
name: Stappers, Benjamin W.
name: Lyne, Andrew G.
name: Mickaliger, Mitchell B.
name: Basu, Avishek
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: For a selection of 35 pulsars with large spin-up glitches ($Δν/ν\geq10^{-6}$), which are monitored by the Jodrell Bank Observatory, we analyse 157 glitches and their recoveries. All parameters are measured consistently and we choose the best model to describe the post-glitch recovery based on Bayesian evidence. We present updated glitch epochs, sizes, changes of spin down rate, exponentially recovering components (amplitude and corresponding timescale) when present, as well as pulsars' second frequency derivatives and their glitch associated changes if detected. We discuss the different observed styles of post-glitch recovery as well as some particularly interesting sources. Several correlations are revealed between glitch parameters and pulsar spin parameters, including a very strong correlation between a pulsar's interglitch $|\ddotν|$ and $\dotν$, as well as between the glitch-induced spin-down rate change $Δ\dotν_{\rm p}$ that does not relax exponentially and $\dotν$. We find that the ratio $\left|Δ\dotν_{\mathrm{p}}/\ddotν\right|$ can be used as an estimate of glitch recurrence times, especially for those pulsars for which there are indications of a characteristic glitch size and interglitch waiting time. We calculate the interglitch braking index $n$ and find that pulsars with large glitches typically have $n$ greater than $3$, suggesting that internal torques dominate the rotational evolution between glitches. The external torque, e.g. from electromagnetic dipole radiation, could dominate the observed $\ddotν$ for the youngest pulsars ($\lesssim10^{4}\;\mathrm{yr}$), which may be expected to display $n\sim3$.
description: 24 pages, 14 figures, 8 tables. Accepted for publication in MNRAS
Role of the transcription factor Jun in inflammation and fibrosis in the kidney
Creators: name: FERNANDO, SANDUNI CHAMIKA
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 320214
subject: Nephrology and urology

description: The protein Jun acts to regulate the expression of a number of specific genes. This study is the first to identify that Jun induces expression of genes involved in the fibrotic response in the kidney. This identifies Jun as a new therapeutic target in the treatment of kidney disease.
Water-dispersible Arsonic Acid Functional Polymer Coated Iron Oxide Nanoparticles as Efficient Imaging Agents
Creators: name: RAJAKANTHAN, ALEXANDER
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 340301
subject: Inorganic materials (incl. nanomaterials)
classificationCode: 400304
subject: Biomedical imaging
classificationCode: 320604
subject: Nanomedicine

description: This thesis examines safer medical imaging alternatives to the typically used Gadolinium-based agents. It identified a new class of nanomaterials that can be used in a range of biomedical applications whilst maintaining low toxicity.
Relazione con i pari e benessere socio-emotivo dei pre-adolescenti nel primo biennio di scuola media
Creators: name: Croci Torti, Elena
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2013

description: Il presente lavoro indaga circa l’influenza che la relazione con i pari può avere sul benessere socio-emotivo dei pre-adolescenti. Per svolgere questa ricerca è stato utilizzato un questionario suddiviso in cinque categorie, nelle quali sono elencate le componenti fondamentali per lo sviluppo. Il questionario è stato somministrato in alcune scuole medie ticinesi a ragazzi che frequentano il primo biennio. È risultato che una buona relazione con i coetanei è direttamente correlata al benessere socio-emotivo del pre-adolescente e inversamente correlata a elementi di malessere. È inoltre correlata all’attuazione di comportamenti prosociali da parte del pre-adolescente accettato dai pari. La relazione con i pari rappresenta dunque un aspetto fondamentale di quell’età, che può avere conseguenze positive sul benessere, ma anche negative nel caso venga a mancare. I dati raccolti e i risultati sono indirizzati a tutti coloro che lavorano o più semplicemente educano dei pre-adolescenti. Relatori: Luciana Castelli, Luca Sciaroni, Alberto Crescentini. Materia: scienze dell’educazione.
Attrezzatura di montaggio e controllo geometrie per unità a motori lineari
Creators: name: Rasero, Nicola
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2024
Subjects: drive unit
linear motor

description: Il presente lavoro si concentra sullo sviluppo di un'attrezzatura automatizzata per l'assemblaggio e il controllo delle unità motrici con assi a motori lineari, commissionato da Mikron SA. L'obiettivo principale è semplificare e automatizzare, dove possibile, il processo di montaggio dei prototipi, attualmente eseguito manualmente, garantendo al contempo la precisione geometrica necessaria per il funzionamento ottimale del sistema. L'attrezzatura progettata consente non solo l'assemblaggio ed eventuale disassemblaggio degli assi X e Y sotto elevati carichi magnetici, ma anche la verifica della precisione di ciascun asse sia singolarmente sia in modalità combinata. Il progetto prevede la creazione di un modello 3D dettagliato, la documentazione d'uso e una valutazione economica della soluzione proposta. Le tecnologie impiegate includono tecniche avanzate di progettazione e fabbricazione, metrologia, elettrotecnica e automazione, assicurando un prodotto finale che risponda agli elevati standard richiesti in termini di precisione, affidabilità e facilità d'uso. ____ This work focuses on the development of automated assembly and control equipment for drive units with linear motor axes, commissioned by Mikron SA. The main objective is to simplify and automate, where possible, the prototype assembly process, which is currently performed manually, while guaranteeing the geometric precision required for optimal system operation. The designed equipment allows not only the assembly and possible disassembly of the X and Y axes under high magnetic loads, but also the verification of the precision of each axis both individually and in combined mode. The project includes the creation of a detailed 3D model, user documentation and an economic evaluation of the proposed solution. The technologies employed include advanced design and manufacturing techniques, metrology, electrical engineering and automation, ensuring a final product that meets the high standards required in terms of precision, reliability and ease of use.
Manipulative actions and meaning in Greco-Roman ritual analogy
Creators: name: MOORREES, SASKIA CLAIRE MARSH
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 430314
subject: History of religion
classificationCode: 430305
subject: Classical Greek and Roman history

description: This thesis examines the relationship between ritual action and intended effect during the Greco-Roman period. Three specific types of actions are analysed--binding, depositing, and burning--using both textual and archaeological material, such as curse tablets and figurines. The effects that ritual practitioners aimed to produce through these actions are identified, and geographic and temporal trends are examined from these findings. This overall analysis contributes to our understanding of how ancient ritual practitioners constructed the meaning of certain actions, and how this knowledge of ritual analogy was transmitted around the Mediterranean.
SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells
Creators: name: Takahashi, Masayuki
name: Contu, Viorica Raluca
name: Chihana Kabuta
name: Hase, Katsunori
name: Fujiwara, Yuuki
name: Wada, Keiji
name: Kabuta, Tomohiro
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology

description: Single-stranded oligonucleotides (ssOligos) are efficiently taken up by living cells without the use of transfection reagents. This phenomenon called ‘gymnosis’ enables the sequence-specific silencing of target genes in various types of cells. Several antisense ssOligos are used for the treatment of human diseases. However, the molecular mechanism underlying the uptake of naked ssOligos into cells remains to be elucidated. Here, we show that systemic RNA interference deficient-1 (SID-1) transmembrane family 2 (SIDT2), a mammalian ortholog of the Caenorhabditis elegans double-stranded RNA channel SID-1, mediates gymnosis. We show that the uptake of naked ssOligos into cells is significantly downregulated by knockdown of SIDT2. Furthermore, knockdown of SIDT2 inhibited the effect of antisense RNA mediated by gymnosis. Overexpression of SIDT2 enhanced the uptake of naked ssOligos into cells, while a single amino acid mutation in SIDT2 abolished this effect. Our findings highlight the mechanism of extra- and intracellular RNA transport and may contribute to the further development of nucleic acid-based therapies.
Utility of 2-(5-Methyl-1-Phenyl-1H-Pyrazol-4-yl)-2-Oxo-N’-Phenylaceto- Hydrazonoyl Bromide as Precursor for Synthesis of New Functionalized Heterocycles
Creators: name: Abdelhamid, Abdou O.
name: Gomha, Sobhi M.
name: Abdelriheem, Nadia A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: 2-(5-Methyl-1-phenyl-1H-pyrazol-4-yl)-2-oxo-N’-phenylacetohydrazonoyl bromide was synthesized and used as precursor for synthesis of some new 1,3,4-thiadiazoles, pyrrolo[3,4-c]pyrazoles and 1,2,4-triazolo[4,3-a]pyrimidines. The mechanisms that account for formation of products were discussed. Also, the structures of all the newly synthesized products were confirmed based on elemental analysis, spectral data and by alternative methods.
Solvent Free Synthesis of Dibenzo[b,j][1,10]Phenanthroline Derivatives Using Eaton's Reagent as Catalyst
Creators: name: Satheeshkumar, Rajendran
name: Prasad, Karnam Jayarampillai Rajendra
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: 60506 Virology
subject: Computational Biology

description: A new class of dibenzo[b,j][1,10]phenanthrolines have been prepared. The synthon acridones were achieved in very good yield by a one-pot reaction of 2-amino-5-chloro or 2′-chloro/flouro substituted benzophenones with 1,2-cyclohexanedione in the presence of freshly prepared Eaton's reagent (phosphorus pentoxide-methanesulfonic acid) without solvent, via Friedländer synthesis. Then these intermediates were reacted with 2-amino-3,5-dibromobenzaldehyde to afford 1,3-dibromo-10-chloro-8-aryl-6,7-dihydrodibenzo[b,j][1,10] phenanthroline. Also an one pot reaction between 2 moles of 2-amino-5-chloro aryl benzophenones with 1 mole of 1,2-cyclohexanedione to get 3,10-dichloro-5,8-diaryl-6,7-dihydrodibenzo[b,j][1,10]phenanthroline has also been reported. The newly synthesized structures of the compounds were deduced by spectroscopic techniques.
Hypotheses for the study on the representative sample of Poles aged 15+
Creators: name: Growiec, Katarzyna
Publisher: name: OSF Registries
Year: 2021

description: We will perform statistical methods (primarily
hierarchical regression models) on a novel cross-sectional survey dataset of a large representative sample of
the Polish population (N=1000). Here we present hypotheses for this part of our project - data from a survey on a representative sample of Poles aged 15+.
title: OFROM: interview avec ilcf22a05
Creators: name: Delafontaine, François
name: RadioFribourg
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.a95b7rm3.v2#86d2c192a3a5e7cbbf9bc0af36f82f471ee40e69
Free-energy landscapes of the coupled conformational transition and inclusion processes of altro-cyclodextrins
Creators: name: Tanfeng Zhao
name: Xueguang Shao
name: Wensheng Cai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Computational Biology

description: Mono-altro-cyclodextrin (altro-CD) may undergo a conformational change of its altropyranose unit when encapsulating guest molecules of different sizes. This conformational transition is found to be coupled to the inclusion processes. In the present contribution, the possible conformational transition pathways in the four (self-)inclusion processes of altro-α and -β-CDs with moieties of variant shapes are explored from the insights of free-energy calculations. The two-dimensional free-energy landscapes characterising the coupled (self-)inclusion and isomerisation processes are determined, and the lowest free-energy pathways (LFEP) connecting the minima of the landscapes are located. The conformational statistics of the altropyranose units along the LFEPs reveal different transition pathways in the four (self-)inclusion processes. It can be concluded that when accommodating a free bulky guest molecule, the altropyranose unit will adjust its conformation to match the guest. However, such induced fit effect in the self-complexation of altro-CD derivatives will be weakened. The conformation of the altropyranose unit changes accompanying the self-complexation, but always adopts the 4C1 one in the self-inclusion complex, irrespective of the shape of the guest moieties. The present results help determine the transition states of the (self-)inclusion processes of CDs and further improve the understanding of the mechanical properties of CD-based molecular shuttles.
title: The archaeological weird
title: excavating the non-human
titleType: Subtitle
Creators: name: Dodd, Kerry
Publisher: name: Lancaster University
Year: 2020
Subjects: Artefacts
Weird Fiction
Archaeology
Science Fiction
Encounter
Lost Cities
Museums
Zones
Space Archaeology
Xenoarchaeology
Xeno-artefacts
object-oriented ontology
Material Culture
non-human
Archaeological Weird

description: The interaction between human and non-human can be visualised through archaeology, the excavation of material culture, which provides a unique insight into frameworks of ontological encounter. Indeed, it is the realisation of how the human subject perceives the non-human that is utilised by both exhibitionary institutions and adventure fiction to elicit a recognition of material ‘identity’ within a viewing subject. Both the visual framings of film and the representative reductionism of prose therefore project narratives about materiality but simultaneously imply that such an identification reflects an emergent ‘object ontology’. Encounters with ‘wonderful things’ or xeno-artefacts may thus appear extraordinary, but become tacitly ‘knowable’ through the way they are framed to the subject. This thesis focuses on the cultural production of the artefact encounter to demonstrate how notions of ‘object identity’ reflect on human perception rather than any realisation of non-human ontology. Analysing the subjective labelling involved within the differentiation of rubbish and relic, the thesis investigates how encounter is fundamental to prescriptions of material value or worth. Literary representation draws upon such a materialist paradigm to evoke a recognition of ‘objects’ and thus provides a platform where such preconceptions can be both identified and confronted. Weird Fiction’s inclination to notions of exteriority is therefore perfectly suited to depictions of contact that eludes a distillation of macro ontologies to micro representations and rather resides within the process of encounter. Yet while Speculative Realist or Object-Oriented thought utilises the Weird to re-conceptualise ontological definitions, this thesis argues that such formations return to a recognition of non-human alterity as lying beyond anthropocentric depiction, rather than confronting the biases within the framework itself. Through artefacts, ruins, zones and xenoarchaeology, this thesis analyses the very processes of encounter to consider how imaginative modes can help underscore the urgency of re-negotiating ontological contact points.
Task-Based Language Learning: ricreare in classe le condizioni per un’autentica esigenza comunicativa. Vantaggi in termini di apprendimento lessicale e di efficacia dell’espressione orale.
Creators: name: Rabbiosi, Giulia
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2018

description: Questo breve lavoro di diploma ha inteso indagare gli effetti dell’utilizzo di un approccio TBLL in una classe di seconda media, per verificare se vi fosse o meno un potenziamento dell’acquisizione del lessico e dell’efficacia dell’espressione orale in francese. Parallelamente si è voluto appurare, tramite la somministrazione iniziale e finale di un questionario, se un percorso didattico incentrato sulla realizzazione di compiti concreti e contestualizzati potesse incrementare la percezione di auto-efficacia negli allievi e il loro gradimento per la materia. Dopo una prima parte dedicata all’inquadramento teorico, si riportano i dettagli di quattro sperimentazioni in cui gli allievi sono stati chiamati a utilizzare la lingua per risolvere situazioni-problema, imparando a comunicare comunicando. Vengono in seguito presi in esame i dati linguistici prodotti da due allievi rappresentativi dei poli estremi nel range dei risultati scolastici della classe e dell’apprezzamento nei confronti della disciplina. Si giunge infine a delle conclusioni che, alla luce dei risultati raccolti, rispondono positivamente ai quesiti di ricerca. Relatrice: Chiara Antonini. Materia: Curriculum plurilingue: Francese, Italiano lingua straniera
title: An analysis of hospital admissions for ambulatory care sensitive conditions
Creators: name: Dixon, J
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2001

description: Aims: To define and identify ‘ambulatory care sensitive’ (ACS) and ‘ambulatory care insensitive' (ACI) conditions. To assess the quality of the NHS hospital episode statistics (HES) dataset. To assess the reasons for variation in hospitalisation for ACS conditions across small areas. To discuss whether variations in admissions for ACS conditions could be used to indicate equity of access to primary care. Main subjects: Hospital admissions for residents of North West Thames NHS region 1991/2, 1992/3, 1993/4. Methods: A modified nominal group technique was used to identify ACS and ACI conditions. The quality of HES was analysed by measuring shortfalls in key fields and the reproducability of clinical coding. Factors influencing variations in hospitalisation were assessed using multivariate analysis. The results were compared to similar studies from the US and Canada. Results: 30 ACS and 66 ‘weakly ACS' conditions were identified. Only S out of the 16 main acute providers serving the North West Thames region had adequate HES data across all three study years. In two providers, the exact clinical codes for main diagnosis could be reproduced in 43% and 60% respectively, and the first 3-digits of the ICD-9 codes in 33% and 72%. A significant positive relationship was found between admissions and socioecononomic deprivation independently of indicators for mortality and morbidity. This was weaker than that between admissions and area income found in the US and Canada. The relationship with deprivation was stronger for ACS than ACI conditions. A significant and positive relationship was found with an indicator of access to hospital care, but not access to primary care. The overall explanatory power of the model was weak at 10-20%. Conclusions: Admissions for ACS conditions are higher in deprived areas, suggesting that access to ambulatory care may be lower. Higher rates of ACS conditions in poor areas in North America suggest lower access to timely and effective ambulatory care than in the UK NHS.
The NanoCommons e-infrastructure – A quick guide to what and how of nanoinformatics in safety assessment suiting basic to expert users in academia, industry, and regulatory agencies
Creators: name: Himly, Martin
name: Farcal, Lucian
name: Papadiamantis, Anastasios
name: Duschl, Albert
name: Lynch, Iseult
Publisher: name: Zenodo
Year: 2020
Subjects: nanoinformatics, hazard assessment, exposure assessment, modelling, data FAIRness, safe-by-design

description: NanoCommons is a research e-infrastructure project offering access to high quality nanoinformatics services for nanosafety assessors in academia, industry, regulatory agencies. It is user-led, offering and developing the services needed by the user community of nanotechnology, nanosafety and related fields. NanoCommons is built on 3 main pillars: joint research activities, networking activities and transnational access services, covering four categories relevant for nanosafety assessment: experimental workflows design and implementation; data processing and analysis; data visualisation and predictive toxicity; data storage and online accessibility. These services are designed to promote data FAIRness (Findable, Accessible, Interoperable, and Reusable), a key NanoCommons goal, that can be made Open through the NanoCommons Knowledgebase. Thus, NanoCommons provides innovative solutions for data mining, harmonisation, utilisation and re-utilisation, including incorporation of a range of modelling and decision support tools that require and/or can produce organised, high-quality datasets. A number of online training tools have been developed for each of the offered services to help users chose the services relevant to their research questions and applications. The NanoCommons infrastructure encompassing a training library shall bridge academic research with industry and regulators, as recommended by the EU NanoSafety Cluster‘s “Closer to the Market” Research Roadmap serving the Safe-by-Design concept in nanotechnology.
description: {"references": ["https://www.openaire.eu/how-to-make-your-data-fair"]}
Emergence and evolution of electronic modes with temperature in spin-gapped Mott and Kondo insulators
Creators: name: Kohno, Masanori
Publisher: name: arXiv
Year: 2024
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Electronic modes emerge within the band gap at nonzero temperature in strongly correlated insulators such as Mott and Kondo insulators, exhibiting momentum-shifted magnetic dispersion relations from the band edges. As the temperature increases, the emergent modes gain considerable spectral weights and form robust bands that differ from the zero-temperature bands. Here, the origin of the emergent modes, their relation to doping-induced modes, and how their spectral weights increase with temperature are clarified in the ladder and bilayer Hubbard models and one- and two-dimensional Kondo lattice models using effective theory for weak inter-unit-cell hopping and numerical calculations. The results indicate that the temperature-driven change in the band structure reflecting spin excitation, including the change in the number of bands, can be observed in various strongly correlated insulators even with a spin gap, provided that the temperature increases up to about spin-excitation energies. The controlled analyses developed in this study significantly contribute to the fundamental understanding of the band structure of strongly correlated insulators at nonzero temperature.
description: 21 pages, 10 figures, 3 tables
Genetic variation and clonal diversity in introduced populations of Mimulus guttatus assessed by genotyping at 62 single nucleotide polymorphism loci
Creators: name: Pantoja, Pauline O.
name: Simón-Porcar, Violeta I.
name: Puzey, Joshua R.
name: Vallejo-Marín, Mario
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Background: Single nucleotide polymorphisms (SNPs) are increasingly being used to study non-native populations. SNPs are relatively information poor on a per locus basis, but allow genotyping more loci than others markers (e.g., microsatellites) and have the advantage of consistent allele calls between studies. Aims: We investigated the utility of a newly developed set of SNP markers, suitable for high throughput genotyping to characterise genotypic variation and population structure in non-native populations of the facultative clonal herb Mimulus guttatus in the United Kingdom (UK). Methods: We analysed 62 SNP markers and using a high throughput platform genotyped 383 individuals from 10 populations from the native range in North America and 14 populations in the UK. Results: We found wide variation in genotypic diversity within UK populations, indicating reproductive strategies that vary from mostly clonal to mostly sexual. All but one UK population were, on average, more closely related to each other than to North American populations, and the exceptional UK population showed strong affinity to native Alaskan plants. Conclusions: A small number of SNPs can detect patterns of clonality and broad-scale relationships between native and introduced populations. However, elucidating population structure at a finer scale will require genotyping individuals at greater depth.
Computationally connecting organic photovoltaic performance to atomistic arrangements and bulk morphology
Creators: name: Jones, Matthew L.
name: Jankowski, Eric
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Rationally designing roll-to-roll printed organic photovoltaics (OPVs) requires a fundamental understanding of active layer morphologies optimised for charge separation and transport, and which ingredients can be used to self-assemble those morphologies. In this review article we discuss advances in three areas of computational modelling that provide insight into active layer morphology and the charge transport properties that result. We explain the computational bottlenecks prohibiting atomistically-detailed simulations of device-scale active layers and the coarse-graining and hardware acceleration strategies for overcoming them. We review coarse-grained simulations of OPV active layers and show that high throughput simulations of experimentally-relevant length scales are now accessible. We describe a new Python package diffractometer that permits grazing-incidence X-ray scattering patterns of simulated active layers to be compared against experiments. We explain the accurate calculation of charge-carrier mobilities from coarse-grained active layer morphologies by using atomistic backmapping, quantum chemical calculations, and kinetic Monte Carlo simulations. We employ these simulations to show that ordering of poly(3-hexylthiophene-2,5-diyl) explains a factor of 1000 improvement in charge mobility. In concert, we present a suite of computational tools enabling large-scale electronic properties of organic photovoltaics to be studied and screened for by molecular simulations.
title: Transcription du manuscrit de Semur-en-Auxois, Bibliothèque Municipale, ms. 1, p. 86
Creators: name: Aubert, Eduardo Henrik
name: Brochard, Pierre
name: Brochard, Pierre
name: Aubert, Eduardo Henrik
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: subject: Laboratoire de médiévistique occidentale de Paris
subject: Semur-en-Auxois
subject: LaMOP

description: Transcription du manuscrit de Semur-en-Auxois, Bibliothèque Municipale, ms. 1, p. 86

production-software: eScriptorium + Kraken version 3.0.13 (PageXml)
description: Source: https://www.nakala.fr/10.34847/nkl.8cee4i4g
description: Source: https://www.nakala.fr/10.34847/nkl.e905tdea
description: Relation: https://lamop.hypotheses.org/
description: Transcription du manuscrit Semur-en-Auxois, Bibliothèque Municipale, ms. 1
description: Transcription du manuscrit Semur-en-Auxois, Bibliothèque Municipale, ms. 1