cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Das Theater der Unterdrückten - Transfermöglichkeiten in die Schule
Creators: name: Spindler, Peter
Year: 2009

description: Die vorliegende Diplomarbeit beschäftigt sich mit den Methoden des Theaters der Unterdrückten von Augusto BOAL. Es wurden Überlegungen zur Umsetzung grundsätzlicher Rahmenbedingungen in den Geographie- und Wirtschaftskunde Unterricht angestellt. Mein Anspruch war es, im Allgemeinen eine gut strukturierte Einführung (vgl. Kapitel 1 - 4) in die theaterpädagogische Arbeit im Schulunterricht sowie in die wichtigsten Methoden des Theaters der Unterdrückten zu bieten und im Speziellen, konkrete Vorschläge für deren Umsetzbarkeit im Geographie- und Wirtschaftskunde Unterricht anzubieten. Das Bindeglied zwischen Einführung in die Thematik und der praktischen Anwendbarkeit der Methoden stellt die Gegenüberstellung zentraler Säulen der kritisch-konstruktiven Didaktik dar (vgl. Kapitel 5). Das Kapitel sechs beschäftigt sich mit den Querschnittsmengen sowie Unterschieden beider zentraler Säulen sowie dem Dilemma zwischen schülerInnenorientierten Unterricht und Fremdbestimmung durch den Lehrplan. Im Kapitel acht wird der Versuch einer modellhaft praktischen Umsetzung angestellt. Eine Gliederung in fünf Schritten soll der/dem LeserIn die Anwendung in der Praxis erleichtern. So auch die vier von mir entwickelten Forumtheaterszenen sollen dem besseren Verständnis dienen. Den Abschluss dieser Arbeit stellt meine persönliche Interpretation der aktuellen Situation des Theaters der Unterdrückten in der Schule dar.
Cyanus uysalii Negaresh
Creators: name: Negaresh, Kazem
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Cyanus
Cyanus uysalii

description: Cyanus uysalii (Şirin & Çeçen) Negaresh, comb. nova.
Basionym: Centaurea uysalii Şirin & Çeçen (2019: 810).
Type:— Turkey. C4 Karaman: Çakırdağı, between Kavurgalık hill and Pelitli stream, rocky area, 1270–1390 m, 37° 23′ 11″ N, 33° 29′ 26″ E, 1 May 2018, Şirin & Çeçen 733 (holotype KNYA!, isotype ANK).
Relationships: — Cyanus uysalii belongs to C. sect. Protocyanus (Dobroczajeva 1949: 64) Olšavská (2013: 253), which includes taxa with perennial habit. It is similar to C. bourgaei, which is endemic to Turkey, in life from, shape of roots and pairs of lateral segments in its rosette leaves, but differs in some important characters such as stem ascending to decumbent, 12–20 cm long (vs. mostly ascending, 3–10 cm long), rosette leaves generally pinnatipartite (vs. lyrate), involucres 12–13 × 9–11 mm (vs. 15–17 × 10–13 mm), central florets 13–14 mm (vs. 16–17 mm) long, peripheral florets 20–21 mm (vs. 25–26 mm) long, median phyllaries obtuse, 8–9 × 2–3 mm (vs. acute, 9–10 × 3–4 mm), achenes 3.6–3.9 × 1.6–1.9 mm (vs. 4.5–5 × 2.5–2.9 mm), and also hilum sparsely hairy (vs. densely hairy).
In addition, C. uysalii shares some characters such as indumentum and habit with C. pichleri (Boissier 1875: 638) Holub (1973: 144). The latter species is distributed in Turkey and Greece (Wagenitz 1975). However, its marked differences in stem 12–20 cm (vs. 6–12 cm) length, rosette leaves generally pinnatipartite and with 1–5 pairs of lateral segments (vs. entire or with large lanceolate terminal segment and l–2(–3) pairs of short lateral lobes or teeth), involucres ovoid-subglobose (vs. ovoid to funnel shaped), peripheral florets blackish-violet or yellowish-white, 20–21 mm long (vs. blue, 23–30 mm long), median appendages 7–10 × 2.5–3 mm (vs. 10–14 × 3.5–5 mm), median phyllaries obtuse (vs. acute), and also achenes 3.6–3.9 mm (vs. 4–5 mm) long separate C. uysalii easily from the latter.
description: Published as part of Negaresh, Kazem, 2020, Cyanus uysalii (Asteraceae, Cardueae), a new combination for the flora of Turkey, pp. 245-248 in Phytotaxa 440 (3) on pages 245-246, DOI: 10.11646/phytotaxa.440.3.7, http://zenodo.org/record/13872308
Additional file 1 of Confidence intervals for validation statistics with data truncation in genomic prediction
Creators: name: Bermann, Matias
name: Legarra, Andres
name: Munera, Alejandra Alvarez
name: Misztal, Ignacy
name: Lourenco, Daniela
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology

description: Additional file 1: Table S1. Average squared differences between estimated and true variance, lower bound of the 95% confidence interval (lCI), and upper bound of the 95% confidence interval (uCI) for Example 1 for different heritabilities. Table S2. Average squared differences between estimated and true variance, lower bound of the 95% confidence interval (lCI), and upper bound of the 95% confidence interval (uCI) for Example 1 for different proportions of phenotyped animals.
ACTonDiabetes: study protocol of a pragmatic randomised controlled trial for the evaluation of an acceptance and commitment-based internet-based and mobile-based intervention for adults living with type 1 or type 2 diabetes
Creators: name: Bendig, Eileen
name: Schmitt, Andreas
name: Wittenberg, Amelie
name: Kulzer, Bernhard
name: Hermanns, Norbert
name: Moshagen, Morten
name: Baumeister, Harald
name: Dc.Contributor.Author
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: general diabetes
subject: clinical trials
subject: DDC 150 / Psychology
subject: DDC 610 / Medicine & health
subject: Diabetes mellitus; Psychology
subject: Depressive disorder
subject: Mood disorders
subject: Randomized controlled trials as topic
subject: Diabetes mellitus
subject: Depressivität
subject: Klinisches Experiment

description: IntroductionLiving with diabetes can be burdensome and lead to serious emotional distress and impaired mental health. Acceptance and commitment therapy (ACT) can support people facing the challenges of living with diabetes. This trial aims to evaluate the effectiveness and cost-effectiveness of the internet-based and mobile-based intervention (IMI) ‘ACTonDiabetes’ in reducing diabetes distress against enhanced treatment as usual (TAU+) following specialised diabetes care.Methods and analysisA two-armed pragmatic randomised controlled trial will be conducted to evaluate the guided IMI ACTonDiabetes against TAU+. A total of 210 adults with type 1 or type 2 diabetes and elevated diabetes distress (Problem Areas in Diabetes ≥40) will be recruited at a specialised diabetes centre. The intervention begins 2–4 weeks after hospital discharge and takes about 7–10 weeks to complete. Assessments are performed at baseline and 5 and 10 weeks as well as 6 and 12 months after randomisation. The primary outcome is diabetes distress at a 10-week follow-up (T2). Secondary outcomes are depression (Patient Health Questionnaire-8), psychological well-being (WHO-5), quality of life (Assessment of Quality of Life-8 Dimension), Diabetes-related Self-Management Questionnaire, diabetes acceptance (Acceptance and Action Diabetes Questionnaire) and negative treatment effects (Inventory for the Assessment of Negative Effects of Psychotherapy). All statistical analyses will be performed based on the intention-to-treat principle with additional per-protocol analyses. Changes in outcomes will be evaluated using the general linear model. A health-economic evaluation will be conducted from a societal perspective. Reasons for drop-out will be systematically investigated.Ethics and disseminationThis clinical trial has been approved by the State Medical Chamber of Baden-Württemberg (file no. B-F-2019-010). Trial results will be submitted for publication in a peer-reviewed journal and presented at conferences.Trial registration numberDRKS00016738.
sj-docx-1-wso-10.1177_17474930231216339 – Supplemental material for Cerebral microbleeds and asundexian in non-cardioembolic ischemic stroke: Secondary analyses of the PACIFIC-STROKE randomized trial
Creators: name: Balali, Pargol
name: Hart, Robert G
name: Smith, Eric E
name: Saad, Feryal
name: Colorado, Pablo
name: Lemmens, Robin
name: De Marchis, Gian Marco
name: Caso, Valeria
name: Xu, Lizhen
name: Heenan, Laura
name: Connolly, Stuart J
name: Mundl, Hardi
name: Shoamanesh, Ashkan
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Cardiology
subject: Medicine
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-wso-10.1177_17474930231216339 for Cerebral microbleeds and asundexian in non-cardioembolic ischemic stroke: Secondary analyses of the PACIFIC-STROKE randomized trial by Pargol Balali, Robert G Hart, Eric E Smith, Feryal Saad, Pablo Colorado, Robin Lemmens, Gian Marco De Marchis, Valeria Caso, Lizhen Xu, Laura Heenan, Stuart J Connolly, Hardi Mundl and Ashkan Shoamanesh in International Journal of Stroke
Additional file 1 of Joint analysis of mutational and transcriptional landscapes in human cancer reveals key perturbations during cancer evolution
Creators: name: Cho, Jae-Won
name: Cao, Jingyi
name: Hemberg, Martin
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. Supplementary Information. Supplementary Information for Figure S1 ~ S9.
IT-Sicherheit, Unternehmenskulturen und wirtschaftsbedrohende Kriminalität
Creators: name: Übelacker, Sven
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: IT-Sicherheit
subject: DDC 330 / Economics
subject: Computer security
subject: Computerkriminalität
subject: Unternehmenskultur

description: Aktualisierte Version der Diplomarbeit von 2002. Wirtschaftskriminalität nimmt seit Ende des Kalten Krieges weltweit einen immer größeren Stellenwert ein. Dabei sind viele Unternehmen nur dürftig geschützt. Durch die weitgehende digitale Vernetzung kommen neue Gefahren auf Unternehmen zu, die eine neue Dimension der Kriminalität darstellen. Mit Sicherheitsanwendungen auf IT-Ebene wird versucht, Cybercrime zu begegnen. Doch sollte der Blick nicht immer auf externe Gefahren gerichtet sein: Innentäter sind nicht zu unterschätzen und brauchen keine gut administrierten Firewalls zu umgehen. Hier spielt das Verhältnis zwischen Mitarbeiter und Unternehmen eine wichtige Rolle, also inwiefern sich ein Mitarbeiter mit seinem Unternehmen identifizieren kann. Großen Einfluss hierauf hat die vorherrschende Unternehmenskultur, in der sich sowohl - teilweise rituell geprägte - Umgangs- und Kommunikationsformen als auch Führungsstile manifestieren. Die Arbeit soll einerseits einen Überblick über die IT-Gefahren und ihre Lösungsmöglichkeiten geben, die die Unternehmenssicherheit erhöhen, andererseits aber auch funktionale und dysfunktionale Effekte von Unternehmenskulturen hinterfragen.
sj-docx-1-ppj-10.1177_17504589231215927 – Supplemental material for Ultrasound-based Accuro system versus traditional palpation technique for neuraxial anaesthesia: A systematic review and meta-analysis of randomised controlled trials
Creators: name: Sharapi, Mahfouz
name: Afifi, Eslam
name: Al Mawla, Aya Mustafa
name: Yassin, Mazen Negmeldin Aly
name: Awwad, Sara Adel
name: El-Samahy, Mohamed
Publisher: name: SAGE Journals
Year: 2023
Subjects: Emergency Medicine

description: Supplemental material, sj-docx-1-ppj-10.1177_17504589231215927 for Ultrasound-based Accuro system versus traditional palpation technique for neuraxial anaesthesia: A systematic review and meta-analysis of randomised controlled trials by Mahfouz Sharapi, Eslam Afifi, Aya Mustafa Al Mawla, Mazen Negmeldin Aly Yassin, Sara Adel Awwad and Mohamed El-Samahy in Journal of Perioperative Practice
EMPLOYEE WELL-BEING, CITIZENSHIP BEHAVIOR, AND PERFORMANCE: UNDERSTANDING THE MEDIATING EFFECTS OF WORKPLACE HAPPINESS AND EXHAUSTION
Creators: name: PINKY PININTA DEWI
name: Dr. SLAMET RIYADI
name: Dr. RIYADI NUGROHO
Publisher: name: Zenodo
Year: 2024
Subjects: Employee Well-Being, Organizational Citizenship Behavior, Happiness at Work, Exhaustion, Individual Performance.

description: Abstract

In the context of PT. Pelindo Daya Sejahtera, the organization's activities are closely connected to the welfare of its employees. The leadership consistently demonstrates efforts to provide support aimed at enhancing performance and rapidly addressing any issues related to employee activities within the company. This underscores the commitment to employee welfare at PT. Pelindo Daya Sejahtera, which effectively motivates employees to meet established work targets. This study seeks to examine the impact of Employee Well-Being and Organizational Citizenship Behavior on Individual Performance, with Happiness at Work and Exhaustion as intervening variables at PT. Pelindo Daya Sejahtera. Employing a quantitative approach, questionnaires were distributed to 150 respondents who were employees of PT. Pelindo Daya Sejahtera, and the data was subsequently analyzed using SMART-PLS. The findings reveal a robust influence of Employee Well-Being on Happiness at Work and Exhaustion, as well as a substantial influence of Organizational Citizenship Behavior on Happiness at Work and Exhaustion. Moreover, Happiness at Work and Exhaustion significantly impact individual performance. Notably, Exhaustion mediates the relationship between employee well-being and individual performance, while it does not mediate the relationship between OCB and individual performance. Additionally, Happiness at Work mediates the relationship between well-being and OCB on individual performance.
Enroll-HD: an integrated clinical research platform and worldwide observational study for huntington's disease
Creators: name: Sathe, Swati
name: Ware, Jen
name: Levey, Jamie
name: Neacy, Eileen
name: Blumenstein, Robi
name: Noble, Simon
name: Mühlbäck, Alzbeta
name: Rosser, Anne
name: Landwehrmeyer, G. Bernhard
name: Sampaio, Cristina
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Huntington's disease
subject: disease network
subject: registry
subject: clinical research platform
subject: longitudinal observational cohort study
subject: Enroll-HD
subject: DDC 610 / Medicine & health
subject: Huntington disease
subject: Research
subject: Cohort studies
subject: Huntington-Chorea
subject: Forschung

description: Established in July 2012, Enroll-HD is both an integrated clinical research platform and a worldwide observational study designed to meet the clinical research requirements necessary to develop therapeutics for Huntington's disease (HD). The platform offers participants a low-burden entry into HD research, providing a large, well-characterized, research-engaged cohort with associated clinical data and biosamples that facilitates recruitment into interventional trials and other research studies. Additional studies that use Enroll-HD data and/or biosamples are built into the platform to further research on biomarkers and outcome measures. Enroll-HD is now operating worldwide in 21 countries at 159 clinical sites across four continents—Europe, North America, Latin America, and Australasia—and has recruited almost 25,000 participants, generating a large, rich clinical database with associated biosamples to expedite HD research; any researcher at a verifiable research organization can access the clinical datasets and biosamples from Enroll-HD and nested studies. Important operational features of Enroll-HD include a strong emphasis on standardization, data quality, and protecting participant identity, a single worldwide study protocol, a flexible EDC system capable of integrating multiple studies, a comprehensive monitoring infrastructure, an online portal to train and certify site personnel, and standardized study documents including informed consent forms and contractual agreements.
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 331 (45. Jg.), Februar 2015
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Uni Ulm intern
subject: DDC 050 / General serial publications
subject: Universities; Germany; Ulm
subject: Universität Ulm

description: uni ulm intern, Das Ulmer Universitätsmagazin, Heft Nr. 331 (45. Jg.), Februar 2015
Mixed-halide triphenyl methyl radicals for siteselective functionalization and polymerization
Creators: name: Chen, Lisa
name: Arnold, Mona
name: Blinder, Rémi
name: Jelezko, Fedor
name: Kuehne, Alexander J. C.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: LIGHT-EMITTING-DIODES
subject: SET MODEL CHEMISTRY
subject: HALOTOLUENE DERIVATIVES
subject: ROTATIONAL-ISOMERISM
subject: TOTAL ENERGIES
subject: SHELL
subject: DDC 540 / Chemistry & allied sciences
subject: Proton magnetic resonance
subject: Atoms
subject: Atom

description: Derivatives of the stable, luminescent tris-2,4,6-trichlorophenylmethyl (TTM) radical exhibit unique doublet spin properties that are of interest for applications in optoelectronics, spintronics, and energy storage. However, poor reactivity of the chloride-moieties limits the yield of functionalization and thus the accessible variety of high performance luminescent radicals. Here, we present a pathway to obtain mixed-bromide and chloride derivatives of TTM by simple Friedel–Crafts alkylation. The resulting radical compounds show higher stability and site-specific reactivity in cross-coupling reactions, due to the better leaving group character of the para-bromide. The mixed halide radicals give access to complex, and so far inaccessible luminescent open-shell small molecules, as well as polymers carrying the radical centers in their backbone. The new mixed-halide triphenyl methyl radicals represent a powerful building block for customized design and synthesis of stable luminescent radicals.
title: Der globale Klimawandel in ausgewählten österreichischen Geographie und Wirtschaftskunde Schulbüchern vor dem Hintergrund der aktuellen Diskussion
Creators: name: Böhm, Matthias
Year: 2009

description: Diese Diplomarbeit befasst sich mit den Beiträgen zum Klimawandel der in Österreich zugelassenen Geographie-Schulbücher. Ziel ist eine Analyse des vorhandenen Angebots zum Thema unter Berücksichtigung der großen gesellschaftlichen Bedeutung des Themas, sowie die Erarbeitung alternativer Herangehensweisen an den Themenkreis im Unterricht.
sj-docx-1-eab-10.1177_00139165221129550 – Supplemental material for Multilevel Evidence for the Parent-Adolescent Dyadic Effect of Familiarity With Climate Change on Pro-Environmental Behaviors in 14 Societies: Moderating Effects of Societal Power Distance and Individualism
Creators: name: Xia, Weiwei
name: Li, Liman Man Wai
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-eab-10.1177_00139165221129550 for Multilevel Evidence for the Parent-Adolescent Dyadic Effect of Familiarity With Climate Change on Pro-Environmental Behaviors in 14 Societies: Moderating Effects of Societal Power Distance and Individualism by Weiwei Xia and Liman Man Wai Li in Environment and Behavior
sj-docx-1-jiv-10.1177_08862605221127215 – Supplemental material for A Vignettes-Based Exploration of Attitudes of Parents Toward Reporting of Child Sexual Abuse in Ghana
Creators: name: Amo-Adjei, Joshua
name: Deliege, Antoine
name: Nurzhynska, Anastasiya
name: Essuman, Ruth
name: Khan, Muhammad Rafiq
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, sj-docx-1-jiv-10.1177_08862605221127215 for A Vignettes-Based Exploration of Attitudes of Parents Toward Reporting of Child Sexual Abuse in Ghana by Joshua Amo-Adjei, Antoine Deliege, Anastasiya Nurzhynska, Ruth Essuman and Muhammad Rafiq Khan in Journal of Interpersonal Violence
Additional file 8 of Joint analysis of mutational and transcriptional landscapes in human cancer reveals key perturbations during cancer evolution
Creators: name: Cho, Jae-Won
name: Cao, Jingyi
name: Hemberg, Martin
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 8. Review history.
Enhanced position verification for VANETs using subjective logic
Creators: name: Van Der Heijden, Rens W.
name: Kargl, Frank
name: Abu-Sharkh, Osama M. F.
name: Al-Momani, Ala'a
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Misbehavior detection
subject: Subjective logic
subject: Intrusion detection
subject: Security
subject: DDC 000 / Computer science, information & general works
subject: Vehicular ad hoc networks (Computer networks)
subject: Intrusion detection systems (Computer security)
subject: VANET
subject: Eindringerkennung
subject: Computersicherheit

description: The integrity of messages in vehicular ad-hoc networks has been extensively studied by the research community, resulting in the IEEE 1609.2 standard, which provides typical integrity guarantees. However, the correctness of message contents is still one of the main challenges of applying dependable and secure vehicular ad-hoc networks. One important use case is the validity of position information contained in messages: position verification mechanisms have been proposed in the literature to provide this functionality. A more general approach to validate such information is by applying misbehavior detection mechanisms. In this paper, we consider misbehavior detection by enhancing two position verification mechanisms and fusing their results in a generalized framework using subjective logic. We conduct extensive simulations using VEINS to study the impact of traffic density, as well as several types of attackers and fractions of attackers on our mechanisms. The obtained results show the proposed framework can validate position information as effectively as existing approaches in the literature, without tailoring the framework specifically for this use case.
title: Leistungsphysiologische Aspekte von Rennpferden, Rennkamelen und Rennhunden
Creators: name: Zenz, Maria
Year: 2009

description: Das Ziel dieser Magisterarbeit war es, die kardiovaskulären, respiratorischen und laktatbezogenen Aspekte von Mensch, Rennpferd, Rennkamel und Rennhund zu vergleichen. Dazu wurden Herzfrequenz (HF), Schlagvolumen (SV), Herzminutenvolumen (HMV), Sauerstoffaufnahme (VO2), Kohlendioxidabgabe (VCO2), Atemminutenvolumen (Ventilation, VE), Atemzugvolumen (Tidalvolumen, VT), Atemfrequenz (AF) und Laktatkonzentration im Blut und im Muskel der vier Säuger aus diversen Studien entnommen und einander gegenübergestellt. Deren Ruhe- und Maximalwerte, deren akute Anpassungen an körperliche Belastungen, deren chronische Anpassungen an das Training und deren Verläufe in der Erholungsphase wurden näher beleuchtet. Das Rennpferd besitzt gegenüber dem Rennkamel, dem Menschen und dem Rennhund sowohl unter Ruhebedingung als auch unter maximaler Belastung die größten absoluten kardiorespiratorischen Parameter. Der Rennhund, der kleinste der vier Säuger, hat wenig überraschend, die geringsten kardiovaskulären und respiratorischen Absolutwerte. In Relation zum Körpergewicht nimmt der Rennhund die erste Stelle ein. Er besitzt gegenüber dem Menschen, dem Rennpferd und dem Rennkamel sowohl unter Ruhebedingung als auch unter maximaler Belastung die größten relativen kardiorespiratorischen Werte. Das Rennkamel erreicht im Bezug zum Körpergewicht die geringsten kardiovaskulären und respiratorischen Parameter. Das bedeutet aber nicht, dass das Rennkamel automatisch am schlechtesten abschneidet. Das Rennkamel besitzt nämlich die Fähigkeit, sich auch bei hohen Geschwindigkeiten mittels Passgangs fortzubewegen. Da bei dieser Gangart der Körperschwerpunkt kaum angehoben werden muss, ist der Energieaufwand um vieles geringer als beispielweise bei einem galoppierenden Pferd. Dadurch erreicht das Rennkamel unter maximaler Belastung niedrigere relative kardiorespiratorische Werte als der Mensch, das Rennpferd und der Rennhund. Des Weiteren häuft das Rennkamel im Gegensatz zu Rennpferd, Rennhund und Mensch erst bei vergleichsweise hohem Arbeitsumsatz Laktat im Blutplasma an.
Scattering of a particle with internal structure from a single slit: exact numerical solutions
Creators: name: Dömötör, Prioska
name: Földi, Péter
name: Benedict, Mihaly G.
name: Shore, Bruce W.
name: Schleich, Wolfgang P.
Publisher: name: Universität Ulm
Year: 2015
Subjects: subject: scattering of structured particles
subject: quantum corrections to rotor passage through aperture
subject: Green’s function
subject: 34.50.-s
subject: DDC 530 / Physics
subject: Multiple scattering (Physics)
subject: Streuung

description: Abstract Scattering of a quantum particle with internal structure is fundamentally different from that of a point particle and shows quantum effects such as the modification of transmission due to tunnelling and trapping of the particle. As in a preceding paper (Shore et al 2014 New J. Phys. 17 013046) we consider a model of a symmetric, rigid rotor travelling through an aperture in a thin but impenetrable screen which is perpendicular to both the direction of motion and the rotation axis. We determine the quantum mechanical properties of this two-dimensional geometrical model using a quasi one-dimensional scattering problem with unconventional boundaries. Our calculations rely on finding the Green's function, which has a direct connection to the scattering matrix. Evaluated on a discrete lattice the Hamiltonian is ‘dressed’ by a self-energy correction that takes into account the open boundary conditions in an exact way. We find that the passage through the aperture can be suppressed or enhanced as a result of the rotational motion. These effects manifest themselves through resonances in the transmission probability as a function of incident energy and symmetry of the incident wavefunction. We determine the density-of-states to reveal the mode structure of resonant states and to exhibit the lifetimes of temporary trapping within the aperture.
IKK2/NF-κB activation in astrocytes reduces amyloid β deposition : a process associated with specific microglia polarization
Creators: name: Yang, Shu
name: Magnutzki, Alexander
name: Alami, Najwa Ouali
name: Lattke, Michael
name: Hein, Tabea Melissa
name: Scheller, Judith Stefanie
name: Kröger, Carsten
name: Oswald, Franz
name: Yilmazer-Hanke, Deniz
name: Wirth, Thomas
name: Baumann, Bernd
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: neuroinflammation
subject: NF-κB
subject: IKK
subject: astrogliosis
subject: microgliosis
subject: microglia polarization
subject: Aβ
subject: plaque clearance
subject: DDC 610 / Medicine & health
subject: Alzheimer Disease
subject: I-kappa B Kinase
subject: Astrocytes
subject: Gliosis
subject: Alzheimerkrankheit
subject: Nuklearfaktor Kappa B
subject: Astrozyt

description: Alzheimer’s disease (AD) is a common neurodegenerative disease that is accompanied by pronounced neuroinflammatory responses mainly characterized by marked microgliosis and astrogliosis. However, it remains open as to how different aspects of astrocytic and microglial activation affect disease progression. Previously, we found that microglia expansion in the spinal cord, initiated by IKK2/NF-κB activation in astrocytes, exhibits stage-dependent beneficial effects on the progression of amyotrophic lateral sclerosis. Here, we investigated the impact of NF-κB-initiated neuroinflammation on AD pathogenesis using the APP23 mouse model of AD in combination with conditional activation of IKK2/NF-κB signaling in astrocytes. We show that NF-κB activation in astrocytes triggers a distinct neuroinflammatory response characterized by striking astrogliosis as well as prominent microglial reactivity. Immunohistochemistry and Congo red staining revealed an overall reduction in the size and number of amyloid plaques in the cerebral cortex and hippocampus. Interestingly, isolated primary astrocytes and microglia cells exhibit specific marker gene profiles which, in the case of microglia, point to an enhanced plaque clearance capacity. In contrast, direct IKK2/NF-κB activation in microglia results in a pro-inflammatory polarization program. Our findings suggest that IKK2/NF-κB signaling in astrocytes may activate paracrine mechanisms acting on microglia function but also on APP processing in neurons.
sj-docx-1-css-10.1177_24705470221128004 - Supplemental material for Proton Magnetic Resonance Spectroscopy in Post-Traumatic Stress Disorder—Updated Systematic Review and Meta-Analysis
Creators: name: Swanberg, Kelley M.
name: Campos, Leonardo
name: Abdallah, Chadi G.
name: Juchem, Christoph
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-docx-1-css-10.1177_24705470221128004 for Proton Magnetic Resonance Spectroscopy in Post-Traumatic Stress Disorder—Updated Systematic Review and Meta-Analysis by Kelley M. Swanberg, Leonardo Campos, Chadi G. Abdallah and Christoph Juchem in Chronic Stress
Chrysosplenol d, a flavonol from Artemisia annua, induces ERK1/2-mediated apoptosis in Triple Negative Human Breast Cancer Cells
Creators: name: Lang, Sophia J.
name: Schmiech, Michael
name: Hafner, Susanne
name: Paetz, Christian
name: Werner, Katharina
name: El Gaafary, Menna
name: Schmidt, Christoph Q.
name: Syrovets, Tatiana
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Triple negative breast cancer
subject: Chrysosplenol d
subject: Chick chorioallantoic membrane assay
subject: Methoxylated flavonoids
subject: Mitogen-activated protein kinase
subject: Casticin
subject: DDC 610 / Medicine & health
subject: DDC 570 / Life sciences
subject: DDC 540 / Chemistry & allied sciences
subject: Breast neoplasms
subject: Mitogen-activated protein kinases
subject: Cell cycle
subject: Artemisia annua
subject: Brustkrebs
subject: Apoptosis
subject: Zellzyklus
subject: Einjähriger Beifuß

description: Triple negative human breast cancer (TNBC) is an aggressive cancer subtype with poor prognosis. Besides the better-known artemisinin, Artemisia annua L. contains numerous active compounds not well-studied yet. High-performance liquid chromatography coupled with diode-array and mass spectrometric detection (HPLC-DAD-MS) was used for the analysis of the most abundant compounds of an Artemisia annua extract exhibiting toxicity to MDA-MB-231 TNBC cells. Artemisinin, 6,7-dimethoxycoumarin, arteannuic acid were not toxic to any of the cancer cell lines tested. The flavonols chrysosplenol d and casticin selectively inhibited the viability of the TNBC cell lines, MDA-MB-231, CAL-51, CAL-148, as well as MCF7, A549, MIA PaCa-2, and PC-3. PC-3 prostate cancer cells exhibiting high basal protein kinase B (AKT) and no ERK1/2 activation were relatively resistant, whereas MDA-MB-231 cells with high basal ERK1/2 and low AKT activity were more sensitive to chrysosplenol d treatment. In vivo, chrysosplenol d and casticin inhibited MDA-MB-231 tumor growth on chick chorioallantoic membranes. Both compounds induced mitochondrial membrane potential loss and apoptosis. Chrysosplenol d activated ERK1/2, but not other kinases tested, increased cytosolic reactive oxygen species (ROS) and induced autophagy in MDA-MB-231 cells. Lysosomal aberrations and toxicity could be antagonized by ERK1/2 inhibition. The Artemisia annua flavonols chrysosplenol d and casticin merit exploration as potential anticancer therapeutics.
A metric to assess the trustworthiness of certificate authorities
Creators: name: Heinl, Michael P.
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Metric
subject: CA
subject: PKI
subject: X.509
subject: Trustworthiness assessment
subject: Digital certificate
subject: DDC 004 / Data processing & computer science
subject: Reliabiltiy
subject: Public key infrastructure
subject: Quantitatives Merkmal
subject: Digitales Zertifikat
subject: Public-Key-Infrastruktur

description: In the recent past, there has been a series of security incidents leading to increasing concern regarding the trust model currently employed by public key infrastructures. One of the key criticisms is the architecture’s implicit assumption that certificate authorities (CAs) are trustworthy a priori. This work proposes a metric to compensate this assumption by a differentiating assessment of a CA’s individual trustworthiness based on objective criteria. The metric utilizes a wide range of factors derived from existing policies, technical guidelines, and research. It consists of self-contained submetrics allowing the simple extension of the existing set of criteria. The focus is thereby on aspects which can be assessed by employing practically applicable methods of independent data collection. The metric is meant to help organizations, individuals, and service providers deciding which CAs to trust or distrust. For this, the modularized submetrics are clustered into coherent submetric groups covering a CA’s different properties and responsibilities. By applying individually chosen weightings to these submetric groups, the metric’s outcomes can be adapted to tailored protection requirements according to an exemplifying attacker model.
description: In der jüngeren Vergangenheit führte eine Reihe von Sicherheitsvorfällen zu Skepsis bezüglich des momentan etablierten Vertrauensmodells von Public-Key-Infrastrukturen. Einer der Hauptkritikpunkte ist dabei die implizite Annahme, dass Zertifizierungsstellen (CAs) a priori vertrauenswürdig sind. Diese Arbeit stellt eine Metrik vor, welche diese Annahme durch eine differenzierte Beurteilung der individuellen Vertrauenswürdigkeit einer CA auf Basis objektiver Kriterien kompensieren soll. Hierfür bedient sie sich einer Vielzahl verschiedener Faktoren aus technischen Richtlinien und Forschungsarbeiten. Die Metrik besteht aus in sich abgeschlossenen Submetriken. Diese ermöglichen eine einfache Erweiterung des bestehenden Kriterienkatalogs. Der Fokus liegt dabei auf Aspekten, welche durch praktisch anwendbare, unabhängige Methoden der Datenerhebung beurteilt werden können. Die Metrik ist dafür vorgesehen, Organisationen, Dienstleistern und Einzelpersonen bei der Entscheidung zu helfen, welchen CAs sie trauen und welchen sie nicht trauen sollten. Die modularisierten Submetriken sind dafür in themenverwandte Gruppen unterteilt, welche verschiedene Eigenschaften und Aufgaben der CAs abdecken. Durch eine individuelle Gewichtung der einzelnen Submetrik-Gruppen kann die Metrik an Hand eines beispielhaften Angreifer-Modells an maßgeschneiderte Schutzbedarfe angepasst werden.
Motion Planning for Connected Automated Vehicles at Occluded Intersections With Infrastructure Sensors
Creators: name: Müller, Johannes
name: Strohbeck, Jan
name: Herrmann, Martin
name: Buchholz, Michael
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Sensors
subject: Junctions
subject: Probabilistic logic
subject: Trajectory
subject: Motion planning
subject: connected automated driving
subject: intersection scenario
subject: DDC 300 / Social sciences
subject: DDC 620 / Engineering & allied operations
subject: Planning
subject: Detectors
subject: Safety
subject: Roads
subject: Automated guided vehicle systems
subject: Verkehrssicherheit
subject: Wahrscheinlichkeitslogik
subject: Straßennetz
subject: Autonomes Fahrzeug

description: Motion planning at urban intersections that accounts for the situation context, handles occlusions, and deals with measurement and prediction uncertainty is a major challenge on the way to urban automated driving. In this work, we address this challenge with a sampling-based optimization approach. For this, we formulate an optimal control problem that optimizes for low risk and high passenger comfort. The risk is calculated on the basis of the perception information and the respective uncertainty using a risk model. The risk model combines set-based methods and probabilistic approaches. Thus, the approach provides safety guarantees in a probabilistic sense, while for a vanishing risk, the formal safety guarantees of the set-based methods are inherited. By exploring all available behavior options, our approach solves decision making and longitudinal trajectory planning in one step. The available behavior options are provided by a formal representation of the situation context, which is also used to reduce calculation efforts. Occlusions are resolved using the external perception of infrastructure-mounted sensors. Yet, instead of merging external and ego perception with track-to-track fusion, the information is used in parallel. The motion planning scheme is validated through real-world experiments.
title: Der Belegarzt
Creators: name: Kuhn, Johannes
Year: 2009

description: Im österreichischen Recht findet sich keine Definition zum Belegarzt, der OGH definiert den Begriff des Belegarztes folgendermaßen: „Ein Belegarzt ist ein Arzt, dem vom Rechtsträger des Belegspitals das Recht gewährt wird, seine Patienten im Belegspital unter Inanspruchnahme der hiefür bereitgestellten Räume und Einrichtungen stationär zu behandeln. Der Belegarzt ist befugt, diese Patienten im Belegspital zu operieren und, solange eine stationäre Behandlung erforderlich ist, dort nachzubehandeln bzw vom Spitalspersonal betreuen zu lassen.“ Belegärzte stehen idR in keinem Anstellungsverhältnis zu der oder den Krankenanstalten, in denen sie belegen. Eine Entgeltbeziehung zwischen Belegärzten und Krankenanstalten besteht nur ausnahmsweise, wenngleich auch nicht ausgeschlossen ist, dass Belegärzte im Rahmen eines Anstellungsverhältnisses allenfalls im Rahmen eines Teilzeitbeschäftigungsverhältnisses tätig werden. In den meisten Belegarztverträgen ist geregelt, dass der Belegarzt einen Anteil seines Honorars für die Infrastruktur des Krankenhauses an die Belegkrankenanstalt abzugeben hat. Diese Abgabe wird als Honorarrücklass, Hausrücklass oder Infrastrukturbeitrag bezeichnet. Die Abänderung des Prozentsatzes bedarf der Zustimmung beider Vertragsparteien. Im Belegarztwesen kommt der gespaltene Krankenhausaufnahmevertrag zur Anwendung. Der Belegarztvertrag regelt das Verhältnis zwischen Belegarzt und Krankenanstalt. Der Patient schließt einerseits einen Behandlungsvertrag mit dem Belegarzt und einen Krankenhausaufnahmevertrag mit dem Rechtsträger der Krankenanstalt. Der Belegarzt hat nach mittlerweile stRsp für die ordnungsgemäße Behandlung des Patienten einzustehen, einerseits was seine eigene Tätigkeit betrifft und andererseits auch was die Mitwirkung aller in seiner Ingerenz stehenden Erfüllungsgehilfen betrifft. Eine Differenzierung nach der Herkunftder Hilfskräfte (Personal des Belegspitals oder außenstehende Dritte) erfolgt nicht, sofern diese Hilfskräfte in gleicher Art und Weise dem Belegarzt bei der Erfüllung seiner vertraglichen Pflicht assistieren. Weder Entgeltlichkeit noch Weisungsgebundenheit stellen haftungsbegründende Kriterien dar. Es ist nicht entscheidungsrelevant, dass der Belegarzt die Anästhesie aufgrund der berufsrechtlichen Bestimmung des § 31 Abs 3 ÄrzteG nicht selbst durchführen darf. Ein weiteres Argument für die Haftung des Belegarztes für eingesetzte Ärzte und Hilfspersonen ist der Aspekt der Rechtssicherheit. Der Patient könnte bei der Rechtsdurchsetzung seiner Interessen Schwierigkeiten haben, herauszufinden, wer passiv legitimiert ist.
Cerebral Microstructural Alterations after Radiation Therapy in High-Grade Glioma: A Diffusion Tensor Imaging-Based Study
Creators: name: Kassubek, Rebecca
name: Gorges, Martin Peter
name: Westhoff, Mike-Andrew
name: Ludolph, Albert C.
name: Kassubek, Jan Rainer
name: Müller, Hans-Peter
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: radiation therapy
subject: fractional anisotropy
subject: white-matter
subject: brain radiotherapy
subject: tumors
subject: diseases
subject: trials
subject: mri
subject: DDC 610 / Medicine & health
subject: Glioblastoma
subject: Glioma
subject: Diffusion tensor imaging
subject: Magnetic resonance imaging
subject: Radiotherapy
subject: Anisotropy
subject: Glioblastom
subject: Gliom
subject: Strahlentherapie
subject: Diffusionsgewichtete Magnetresonanztomografie
subject: Anisotropie

description: Objective To investigate radiation therapy-induced microstructural damage of white matter in patients with high-grade glioma by diffusion tensor imaging (DTI). Methods DTI was performed in 18 patients with high-grade glioma (WHO grades III and IV) and 13 healthy controls. DTI images were cross-sectionally aligned for the calculation of baseline fractional anisotropy (FA). Interhemispheric FA values in patients with high-grade glioma before or without brain radiation therapy were compared with the interhemispheric FA values in patients after radiation therapy and in healthy controls. In a subgroup without any clinical or diagnostic evidence of tumor progression, serial DTI data (5–11 scans) before and after radiation therapy were collected and longitudinal interhemispheric FA changes were assessed and compared to longitudinal data from the control group.In addition, interhemispheric axial, mean, and radial diffusivity was assessed. Results Global interhemispheric FA reductions could be detected cross-sectionally in patients after radiation therapy; these were significantly different from global interhemispheric FA differences both in patients without radiation and in healthy controls. Longitudinal scans in patients with radiation therapy confirmed these findings and revealed progressive microstructural white matter damage after partial brain radiotherapy. The additional DTI metrics axial diffusion, mean diffusivity, and radial diffusion confirmed interhemispheric differences in patients without or before radiation therapy, which were lower than the differences in patients after radiation therapy, although not reaching significance. Conclusion Interhemispheric global FA differences could potentially serve as a biological marker for irradiation-induced microstructural white matter damage.
Performance of different diagnostic PD-L1 clones in head and neck squamous cell carcinoma
Creators: name: Ribbat-Idel, Julika
name: Dressler, Franz F.
name: Krupar, Rosemarie
name: Watermann, Christian
name: Paulsen, Finn-Ole
name: Kuppler, Patrick
name: Klapper, Luise
name: Offermann, Anne
name: Wollenberg, Barbara
name: Rades, Dirk
name: Laban, Simon
name: Reischl, Markus
name: Bruchhage, Karl-Ludwig
name: Idel, Christian
name: Perner, Sven
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: HNSCC
subject: PD-L1
subject: checkpoint inhibitors
subject: TMA
subject: harmonization
subject: therapy prediction
subject: protein quantitation
subject: DDC 610 / Medicine & health
subject: Squamous cell carcinoma of head and neck
subject: Antibodies, Monoclonal
subject: Programmed cell death 1 receptor
subject: Treatment outcome
subject: Plattenepithelcarcinom
subject: Kopf
subject: Hals
subject: Immun-Checkpoint
subject: Therapieerfolg

description: Background: The approval of immune checkpoint inhibitors in combination with specific diagnostic biomarkers presents new challenges to pathologists as tumor tissue needs to be tested for expression of programmed death-ligand 1 (PD-L1) for a variety of indications. As there is currently no requirement to use companion diagnostic assays for PD-L1 testing in Germany different clones are used in daily routine. While the correlation of staining results has been tested in various entities, there is no data for head and neck squamous cell carcinomas (HNSCC) so far. Methods: We tested five different PD-L1 clones (SP263, SP142, E1L3N, 22-8, 22C3) on primary HNSCC tumor tissue of 75 patients in the form of tissue microarrays. Stainings of both immune and tumor cells were then assessed and quantified by pathologists to simulate real-world routine diagnostics. The results were analyzed descriptively and the resulting staining pattern across patients was further investigated by principal component analysis and non-negative matrix factorization clustering. Results: Percentages of positive immune and tumor cells varied greatly. Both the resulting combined positive score as well as the eligibility for certain checkpoint inhibitor regimens was therefore strongly dependent on the choice of the antibody. No relevant co-clustering and low similarity of relative staining patterns across patients was found for the different antibodies. Conclusions: Performance of different diagnostic anti PD-L1 antibody clones in HNSCC is less robust and interchangeable compared to reported data from other tumor entities. Determination of PD-L1 expression is critical for therapeutic decision making and may be aided by back-to-back testing of different PD-L1 clones.
Additional file 10 of circNOX4 activates an inflammatory fibroblast niche to promote tumor growth and metastasis in NSCLC via FAP/IL-6 axis
Creators: name: Zhao, Yan
name: Jia, Yunlong
name: Wang, Jiali
name: Chen, Xiaolin
name: Han, Jingya
name: Zhen, Shuman
name: Yin, Shuxian
name: Lv, Wei
name: Yu, Fan
name: Wang, Jiaqi
name: Xu, Fan
name: Zhao, Xinming
name: Liu, Lihua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 10.
sj-docx-5-aut-10.1177_13623613231215026 – Supplemental material for Perspectives of autistic adolescent girls and women on the determinants of their mental health and social and emotional well-being: A systematic review and thematic synthesis of lived experience
Creators: name: O’Connor, Rachel AG
name: Doherty, Mary
name: Ryan-Enright, Theresa
name: Gaynor, Keith
Publisher: name: SAGE Journals
Year: 2023
Subjects: Psychology not elsewhere classified
Psychiatry (incl. Psychotherapy)
Public Health and Health Services not elsewhere classified
Education
Special Education and Disability

description: Supplemental material, sj-docx-5-aut-10.1177_13623613231215026 for Perspectives of autistic adolescent girls and women on the determinants of their mental health and social and emotional well-being: A systematic review and thematic synthesis of lived experience by Rachel AG O’Connor, Mary Doherty, Theresa Ryan-Enright and Keith Gaynor in Autism
Smart-Akis Recommendations And Fact-Sheets
Creators: name: Bellostas, Natalia
name: Gorriti, Ion
Publisher: name: Zenodo
Year: 2018
Subjects: smartfarming
digitalfarming
precisionag
agriculture
innovation
multi-actor
thematic network
recommendations

description: Smart-AKIS follows the EIP-Agri “multi-actor approach”, implementing an interactive innovation model, for engaging with different stakeholders within and outside the project at regional, national and European level. Through its different activities, the project has gathered insights on the barriers and incentives for the adoption of Smart Farming Technologies (SFT) as well as on the needs from end-users and other stakeholders in the value chain, such as researchers, industry and advisors.

These findings, together with other project’s outcomes, such as the trends on SFT research and industry solutions, have allowed the consortium to produce a set of recommendations for closing the research and innovation divide in the field of SFT in Europe, which are presented in this Deliverable. Being one of the central outcomes of Smart-AKIS, the recommendations have also been drafted in the form of fact-sheets, easily readable documents for wide dissemination among end-users and stakeholders in the value chain.

The Deliverable is divided into four Chapters:

- Chapter 1 makes an introduction to the goals and content of the deliverable.

- Chapter 2 describes the process followed at the overall project level to gain the necessary insights and information for issuing the recommendations. This chapter also presents the background for the choice of fact-sheets template for the wide dissemination of the recommendations.

- Chapter 3 presents the recommendations of Smart AKIS on three different areas: a) Enhancing innovation-driven agricultural research within the EIP-AGRI ecosystem, b) Future research on Smart Farming and c) Recommendations for mainstreaming Smart Farming.

- Chapter 4 sums up the main recommendations for mainstreaming Smart Farming in Europe into Factsheets, easy to read and understand summaries for dissemination purposes.