cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Parent in One Member State, Parent in All Member States: The Good, the Bad and the Ugly
Creators: name: Rakic, Stefan
name: Choi, Jiyu
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2024
Subjects: subject: LGBTIQ parenthood rights
subject: rainbow families
subject: EU fundamental values
subject: legislative initiative
subject: jurisdiction
subject: applicable law

description: European Papers - A Journal on Law and Integration, 2023 8(3), 1555-1574
description: I. Introduction. – II. Rainbow families’ parental rights in the EU: charting progress through law and politics. – II.1. From courtrooms to Commission: the evolution of LGBTIQ parenthood recognition in EU law. – II.2. Political strategy of the Regulation proposal. – III. Concerns on the efficiency of the EU legislative mechanism. – III.1. The ambiguity of “EU value driven policy”. – III.2. The TFEU as an unexpected obstacle. – III.3. The Regulation proposal at an impasse: which alternatives? – IV. Conclusion.
description: The EU is known for its commitment to protecting the fundamental rights of same-sex couples as outlined in art. 10 TFEU and the Charter of Fundamental Rights of the EU (Charter) within its value-driven principles. Nevertheless, same-sex couples still face discrimination in forming families. Only 14 out of 27 Member States allow same-sex marriage, seven offer some form of recognition, and the other six offer no recognition at all. To address this issue, the European Commission has proposed a legal instrument which would introduce uniform rules for jurisdiction and applicable law in matters of parenthood, with the goal of ensuring recognition of parental rights for rainbow families across the EU. While the European Court of Human Rights and the Court of Justice of the European Union have made significant efforts to legally protect LGBTIQ individuals, the EU’s ability to act in the face of anti-LGBTIQ legal and social climates is still being questioned. This Article will examine the contents of the Commission’s legislative proposal, its political strategy, and the practical obstacles to its adoption, including legal mechanisms and political situations in certain Member States. The effectiveness, practicability, and sustainability of the proposal will also be evaluated. The goal is to provide a comprehensive analysis of the Commission’s efforts to promote and protect the rights of same-sex couples in the EU.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2018
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

237 pages (version 8.0).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry featuring two new papers).
Nitrogen triiodide - Molecule of the Month December 2001 [Archived version]
Creators: name: Cotton, Simon
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for December 2001 about nitrogen triiodide. It is a pdf archive version of the HTML webpage.
Methyl jasmonate - Molecule of the Month September 2001 [Archived version]
Creators: name: Cotton, Simon
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for September 2001 about methyl jasmonate. It is a pdf archive version of the HTML webpage.
Micro Pile Foundation In Expansive Soils As An Alternative To Footing Foundation
Creators: name: Mehari Shewangizaw H/Giorgis
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Footing Foundations, Micro pile Foundations, ETABS, Cost breakdown

description: Expansive soil is covering most part of the country and doing construction works on it is
 difficult based on different reasons. Having this type of soil the construction industry in our
 country is using mostly footing foundations for light weight buddings in expansive soils which
 is consuming more money and time. This thesis paper tries to suggest using micro pile
 foundations as an alternative to footing foundations in expansive soils for light weight
 buildings. Light weight buildings are commonly in the process construction in the country
 including low cost condominium buildings.
 This research compares footing and micro pile foundation system for a simple ground + 1
 building profile. The building profile’s force distribution and reaction loads are designed using
 ETABS Software. After calculating the reaction loads this loads are used to design both the
 footing foundations and micro piles including the pile caps. After designing the dimensions of
 the foundation systems the detail quantities of each works are calculated.
 For each type of work specifications a cost break down is done to get the unit prices. Then, the
 final amount of cost for each type of foundation systems is calculated which leads to see which
 type of foundation system is cost effective.
ClF3 - Molecule of the Month June 2001 [Archived version]
Creators: name: Cotton, Simon
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for June 2001 about ClF3. It is a pdf archive version of the HTML webpage.
title: Revenants from the Church to literature
Creators: name: Livermore, Christian
Publisher: name: University of St Andrews
publisherIdentifier: https://ror.org/02wn5qz54
publisherIdentifierScheme: ROR
Year: 2016

description: Factual accounts of revenants – the risen dead – seized the medieval imagination in the early eleventh century, and were recorded by serious historians and ecclesiastics as true. They then began to appear in secular imaginative literature and art, growing progressively more elaborate and frightening throughout the Middle Ages whilst retaining many of the religious overtones expressed overtly in the ecclesiastic tales. By the early modern and modern period, the tales were removed from any overt religious context and were told as purely imaginative literature. The academic half of this thesis explores the influence on the tales of the Christian doctrine of resurrection and the cult of the body of Christ and of the saints, then traces the migration of those tales into imaginative literature from the Middle Ages to the present. It identifies key motifs from the medieval chronicles and imaginative literature that continue to appear in modern stories, and explores the extent to which Christian eschatology altered perceptions of the dead and why, in an increasingly secular context, fascination with such tales continued into modern literature, what part fear of death played throughout this period, and how that fear was expressed, first in an ecclesiastical context, then in imaginative literature through horror stories. The creative half of my thesis is a literary fiction novel updating a medieval revenant tale, the Legend of the Three Living and the Three Dead, to twenty-first century New England.
GREENPEG Deliverable D8.1_Communication Plan, Project Identity kit and Data Management Plan
Creators: name: Reimer, Wolfgang
name: Brönner, Marco
Publisher: name: Zenodo
Year: 2022
Subjects: Communications plan, GREENPEG identity, GREENPEG logo, Data Management Plan, DMP

description: This document establishes the mechanisms for communication, both internally within the project and externally to reach out stakeholders, describes the project identity elements and sets the foundations for the project data management. The latest version of the GREENPEG Data Management Plan (DMP) is written under Appendix 7. Over the course of the project, this will be updated to suit the needs of the project.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2018
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

238 pages (version 8.0).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry featuring two new papers).
Additional file 1 of Response of soil biological properties and bacterial diversity to different levels of nitrogen application in sugarcane fields
Creators: name: Yang, Shangdong
name: Xiao, Jian
name: Liang, Tian
name: He, Weizhong
name: Tan, Hongwei
Publisher: name: figshare
Year: 2021
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Additional file 1: Table S1. The proportion of soil dominant bacterial communities at the phylum level under four N application treatments (%). Table S2. The proportion of soil dominant bacterial communities at genus level under four N application treatments (%).
Lead tetraethyl - Molecule of the Month January 2001 [Archived version]
Creators: name: Cotton, Simon
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for January 2001 about lead tetraethyl. It is a pdf archive version of the HTML webpage.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2018
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

250 pages (version 8.0).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).
title: Mail à Dominique Mathez, transféré le 29 janvier 2008 à Charlotte Lessana
Creators: name: Leibowitch, Jacques
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Texte sur "La forêt sud est du Cameroun là où les prélèvements ont donné" .
description: Source: http://www.calames.abes.fr/pub/ms/Calames-20193111133351211
description: created: start=2008-01-28;end=2008-01-29
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2018
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

271 pages (version 8.1).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).Version 8.1 released 4 October 2018 (one new paper added associated with v 8.0 entry; PDF bookmarks fixed).
A climate network perspective on the intertropical convergence zone
Creators: name: Wolf, Frederik
name: Voigt, Aiko
name: Donner, Reik V.
Publisher: name: Göttingen : Copernicus Publ.
Year: 2021
Subjects: subject: Atmospheric temperature
subject: Belts
subject: Complex networks
subject: Dynamics
subject: Global warming
subject: Hierarchical clustering
subject: Oceanography
subject: FOS: Earth and related environmental sciences
subject: Rain
subject: Surface
subject: Surface properties
subject: Surface waters
subject: Tropics
subject: Global circulation model
subject: Intertropical convergence zone
subject: Model inter comparisons
subject: Network representation
subject: Sea surface temperature (SST)
subject: Spatial correlations
subject: Spatiotemporal variability
subject: Surface temperature anomalies
subject: Climate models
subject: air-sea interaction
subject: climate modeling
subject: Hadley cell
subject: intertropical convergence zone
subject: sea surface temperature
subject: Southern Hemisphere
subject: spatiotemporal analysis
subject: surface temperature
subject: warming
subject: 550

description: The intertropical convergence zone (ITCZ) is an important component of the tropical rain belt. Climate models continue to struggle to adequately represent the ITCZ and differ substantially in its simulated response to climate change. Here we employ complex network approaches, which extract spatiotemporal variability patterns from climate data, to better understand differences in the dynamics of the ITCZ in state-of-the-art global circulation models (GCMs). For this purpose, we study simulations with 14 GCMs in an idealized slab-ocean aquaplanet setup from TRACMIP – the Tropical Rain belts with an Annual cycle and a Continent Model Intercomparison Project. We construct network representations based on the spatial correlation patterns of monthly surface temperature anomalies and study the zonal-mean patterns of different topological and spatial network characteristics. Specifically, we cluster the GCMs by means of the distributions of their zonal network measures utilizing hierarchical clustering. We find that in the control simulation, the distributions of the zonal network measures are able to pick up model differences in the tropical sea surface temperature (SST) contrast, the ITCZ position, and the strength of the Southern Hemisphere Hadley cell. Although we do not find evidence for consistent modifications in the network structure tracing the response of the ITCZ to global warming in the considered model ensemble, our analysis demonstrates that coherent variations of the global SST field are linked to ITCZ dynamics. This suggests that climate networks can provide a new perspective on ITCZ dynamics and model differences therein.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2018
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

273 pages (version 8.2).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).Version 8.1 released 4 October 2018 (one new paper added associated with v 8.0 entry; PDF bookmarks fixed).Version 8.2 released 7 October 2018 (expanded introduction associated with v 8.0 entry).
Nandrolone - Molecule of the Month October 2000 [Archived version]
Creators: name: May, Paul
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for October 2000 about nandrolone. It is a pdf archive version of the HTML webpage.
Chlorophyll - Molecule of the Month May 2000 [Archived version]
Creators: name: May, Paul
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for May 2000 about chlorophyll. It is a pdf archive version of the HTML webpage.
title: The Interplay Between the European Investigation Order and the Principle of Mutual Recognition
Creators: name: Szijártó, István
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2024
Subjects: subject: EIO
subject: mutual recognition
subject: recourse to another investigative measure
subject: enhanced communication
subject: fundamental rights
subject: based refusal ground

description: European Papers - A Journal on Law and Integration, 2023 8(3), 1575-1597
description: I. Introduction. – II. New formulas in the regime of mutual recognition in the EIO. – III. The question of defining investigative measures and having recourse to a different one. – III.1. The applicability of the corrective mechanism in other cooperation systems. – IV. An increased extent of direct communication between the issuing and the executing authorities. – IV.1. Regulating greater communication between issuing and executing authorities as a form of institutionalised distrust. – V. The fundamental rights-based refusal ground and the question of its applicability. – V.1. Making the fundamental rights-based refusal ground the norm instead of it being the exception. – VI. Conclusion.
description: This Article concerns the European Investigation Order (EIO) and its relations to the principle of mutual recognition. The principle has been the engine of judicial cooperation in criminal matters between Member States of the European Union since the adoption of the Tampere conclusions in 1999. Member States rely on the principle in creating cooperation systems, thereby facilitating interaction among their criminal justice systems. Since Member States refrain from extensive criminal law harmonisation, the principle is of utmost importance. As such, a common regulatory technique was developed through which the principle is given effect in every cooperation system created so far. Although this regulatory technique was mostly followed in the directive establishing the EIO, it also introduced several novelties in the regime, notably the option to have recourse to another investigative measure, the possibility for a greater extent of communication, and the fundamental rights-based refusal ground. This Article argues that these rules make the EIO directive more protective of fundamental rights and show a new trend in the cooperation systems based on the principle of mutual recognition. In addition, while reviewing the applicability of these rules in other cooperation systems, it provides a proposal on how to apply them to enhance mutual trust between Member States through legislation.
DNA- Molecule of the Month January 2000 [Archived version]
Creators: name: May, Paul
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for January 2000 about DNA. It is a pdf archive version of the HTML webpage.
Psilocybin and Mescaline - Molecule of the Month October 1999 [Archived version]
Creators: name: May, Paul
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for October 1999 about psilocybin and mescaline. It is a pdf archive version of the HTML webpage.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2019
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

273 pages (version 8.3).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).Version 8.1 released 4 October 2018 (one new paper added associated with v 8.0 entry; PDF bookmarks fixed).Version 8.2 released 7 October 2018 (expanded introduction associated with v 8.0 entry).Version 8.3 released 30 October 2018 (expanded introduction associated with v 8.0 entry; minor addition to earlier entries).
Processes Driving the Variability of the fCO2 in the Southern Ocean AAZ Monitored by a CARIOCA Drifter
Creators: name: Naëck, Kirtana
Publisher: name: Zenodo
Year: 2024

description: Presented at the SO-CHIC and OCEAN:ICE Joint Project Conference, 24 - 25 October 2023, at Sorbonne University, Paris, France.
BANDA Resources and Materials Data Release v1.1
Creators: name: Hubbard, Nicholas A.
name: Bauer, Clemens, C.C.
name: Siless, Viviana
name: Elam, Jennifer
name: Ghosh, Satrajit S.
Publisher: name: Zenodo
Year: 2024
Subjects: Boston Adolescent Neuroimaging of Depression and Anxiety
Connectomes Release to Human Diseases
MRI
depression
anxiety
adolescent
NIMH Data Archive

description: BANDA resources and materials package to accompany BANDA Data Release v1.1.
Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPACdependent pathway
Creators: name: SACHIN SAMUCHIWAL
Publisher: name: figshare
Year: 2017
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60111 Signal Transduction
subject: FOS: Biological sciences

description: p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 9.5px Helvetica} span.s1 {font: 6.0px Helvetica} When activated through toll-like receptors (TLRs), macrophages generate IL-33, an IL-1 family member that induces innate immune responses through ST2 signaling. LPS, a TLR4 ligand, induces macrophages to generate prostaglandin E2 (PGE2) through inducible COX-2 and microsomal PGE2 synthase 1 (mPGES-1) (1). We demonstrate that IL-33 production by bone marrow-derived murine macrophages (bmMFs) requires the generation of endogenous PGE2 and the intrinsic expression of EP2 receptors to amplify NF-B-dependent, LPS-induced IL-33 expression via exchange protein activated by cAMP (EPAC). Compared with WT cells, bmMFs lacking either mPGES-1 or EP2 receptors displayed reduced LPS-induced IL-33 levels. A selective EP2 agonist and, to a lesser extent, EP4 receptor agonist potentiated LPS-induced IL-33 generation from both mPGES-1-null and WT bmMFs, whereas EP1 and EP3 receptor agonists were inactive. The effects of PGE2 depended on cAMP, were mimicked by an EPAC-selective agonist, and were attenuated by EPAC-selective antagonism and knockdown. LPS-induced p38 MAPK and NF-B activations were necessary for both IL-33 production andPGE2 generation, and exogenousPGE2 partly reversed the suppression of IL-33 production caused by p38 MAPK and NF-B inhibition. Mice lacking mPGES-1 showed lower IL-33 levels and attenuated lung inflammation in response to repetitive Alternaria inhalation challenges. Cumulatively, our data demonstrate that endogenousPGE2, EP2 receptors, andEPACare prerequisites for maximal LPS-induced IL-33 expression and that exogenous PGE2 can amplify IL-33 production via EP2 and EP4 receptors. The ubiquitous induction of mPGES-1-dependent PGE2 may be crucial for innate immune system activation during various IL-33 driven pathologic disorders.
Enhanced adhesion of blood platelets to intact endothelium of mesenteric vascular bed in mice with streptozotocin-induced diabetes is mediated by an up-regulated endothelial surface deposition of VWF – In vivo study
Creators: name: Przygodzki, Tomasz
name: Talar, Marcin
name: Kassassir, Hassan
name: Lukasz Mateuszuk
name: Musial, Jacek
name: Watala, Cezary
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Numerous in vitro experiments have confirmed that a dysfunctional endothelium is characterized by, inter alia, a higher affinity for binding of platelets and leukocytes. However, there is still no direct evidence for greater interaction between platelets and intact endothelium in in vivo animal models of diabetes. Therefore, the present study examines the pro-adhesive properties of endothelium change in vivo as an effect of streptozotocin (STZ)-induced diabetes and the role of two key platelet receptors: GPIb-IX-V and GPIIb/IIIa. Mice of C57BL strain with streptozotocin-induced diabetes were used in the study. Flow cytometry was used to assess basal activation and reactivity of platelets. Adhesion of platelets to the vascular wall was visualized with the use of intravital microscopy in mesentery. The contribution of GPIIb/IIIa and GPIb-IX-V was evaluated by the injection of Fab fragments of respective antibodies. The integrity of the endothelium and vWf expression were evaluated histochemically. Basal activation and reactivity of platelets in streptozotocin-diabetic mice were elevated. Blood platelets adhered more often to the vascular wall of diabetic mice than nondiabetic animals: 11.9 (6.4; 32.8) plt/min/mm2 (median [IQR]) vs 2.7 (1.3; 6.4) plt/min/mm2. The injection of anti-GPIbα antibodies decreased the number of adhering platelets from 89.5 (34.0; 113.1) plt/min/mm2 (median [IQR]) in mice treated with isotype antibodies to 3.1 (1.7; 5.6) plt/min/mm2 in mice treated with blocking antibodies. The effect of GPIIb/IIIa blockage was not significant. Immunohistochemistry revealed a higher expression of vWF in the endothelium of STZ mice, but no substantial changes in endothelial morphology were detected. To conclude, the study shows that the platelets interact more frequently with the mesenteric vascular bed in mice with 1-month STZ-induced diabetes than in healthy mice. These interactions are mediated via platelet GPIb-IX-V and are driven by increased expression of vWF in endothelial cells.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2019
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

276 pages (version 9.0).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).Version 8.1 released 4 October 2018 (one new paper added associated with v 8.0 entry; PDF bookmarks fixed).Version 8.2 released 7 October 2018 (expanded introduction associated with v 8.0 entry).Version 8.3 released 30 October 2018 (expanded introduction associated with v 8.0 entry; minor addition to earlier entries).Verion 9.0 released 16 March 2019 (new entry).
p53 and Mdm2 act synergistically to maintain cardiac homeostasis and mediate cardiomyocyte cell cycle arrest through a network of microRNAs
Creators: name: Stanley-Hasnain, Shanna
name: Hauck, Ludger
name: Grothe, Daniela
name: Roozbeh Aschar-Sobbi
name: Beca, Sanja
name: Butany, Jagdish
name: Backx, Peter H.
name: Mak, Tak W.
name: Billia, Filio
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Computational Biology

description: Defining the roadblocks responsible for cell cycle arrest in adult cardiomyocytes lies at the core of developing cardiac regenerative therapies. p53 and Mdm2 are crucial mediators of cell cycle arrest in proliferative cell types, however, little is known about their function in regulating homeostasis and proliferation in terminally differentiated cell types, like cardiomyocytes. To explore this, we generated a cardiac-specific conditional deletion of p53 and Mdm2 (DKO) in adult mice. Herein we describe the development of a dilated cardiomyopathy, in the absence of cardiac hypertrophy. In addition, DKO hearts exhibited a significant increase in cardiomyocyte proliferation. Further evaluation showed that proliferation was mediated by a significant increase in Cdk2 and cyclin E with downregulation of p21Cip1 and p27Kip1. Comparison of miRNA expression profiles from DKO mouse hearts and controls revealed 11 miRNAs that were downregulated in the DKO hearts and enriched for mRNA targets involved in cell cycle regulation. Knockdown of these miRNAs in neonatal rat cardiomyocytes significantly increased cytokinesis with an upregulation in the expression of crucial cell cycle regulators. These results illustrate the importance of the cooperative activities of p53 and Mdm2 in a network of miRNAs that function to impose a barrier against aberrant cardiomyocyte cell cycle re-entry to maintain cardiac homeostasis.
Nitrous Oxide - Molecule of the Month June 1999 [Archived version]
Creators: name: May, Paul
name: Cameron, Ewan
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for June 1999 about nitrous oxide. It is a pdf archive version of the HTML webpage.
title: Reform of Epidemic Surveillance Exposing “Standardising” Decisions and Their Replacements by Regulations
Creators: name: Krepelka, Filip
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2024
Subjects: subject: European Union
subject: secondary law
subject: decision
subject: regulation
subject: law-making
subject: official languages

description: European Papers - A Journal on Law and Integration, 2023 8(3), 1599-1628
description: I. Introduction. – II. Reform of epidemic surveillance. – III. Limited attention to decisions. – IV. Linguistic dimension. – V. Diversity and incidence of decisions. – VI. Inspiration for comparison. – VII. Substantial classification of decisions. – VIII. Outlining the doctrine of “standardising” decisions. – IX. Identified replacements by regulations. – X. Evaluation of these replacements. – XI. Perspectives andlimits of the tendency. – XII. Envisaged reform of secondary law instruments. – XIII. Conclusions.
description: The reform of epidemic surveillance in the European Union as a reaction to the Covid-19 pandemic attracts attention to one sporadically discussed phenomenon. Following the usual meaning of this term in legal settings, many decisions address individual cases. Nevertheless, a new category of decisions establishing rules has emerged in the past decades, i.e. “standardising” (“normative”, “norm-setting”, or “general”) decisions. These decisions have addressed the cooperation between the EU and national authorities, funding programmes and assistance to foreign countries. The European Parliament and the Council approved them. Theoretical reflections on these decisions are rare, but their pitfalls are identifiable. Namely, their possible effects on individuals are limited. The definition of unaddressed decisions provided by the Lisbon Treaty did not clarify the situation. Therefore, the recent tendency to replace these decisions with regulations deserves attention.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2019
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

279 pages (version 10.0).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).Version 8.1 released 4 October 2018 (one new paper added associated with v 8.0 entry; PDF bookmarks fixed).Version 8.2 released 7 October 2018 (expanded introduction associated with v 8.0 entry).Version 8.3 released 30 October 2018 (expanded introduction associated with v 8.0 entry; minor addition to earlier entries).Version 9.0 released 16 March 2019 (new entry).Version 10.0 released 7 April 2019 (new entry; minor update to previous entry).
ATP - Molecule of the Month January 1998 [Archived version]
Creators: name: May, Paul
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for January 1998 about ATP. It is a pdf archive version of the HTML webpage.
LSD - Molecule of the Month December 1998 [Archived version]
Creators: name: May, Paul
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for December 1998 about LSD. It is a pdf archive version of the HTML webpage.
Schediasma Musei Lucernensis Langiani
Creators: name: Unkown
Publisher: name: Zenodo
Year: 1700

description: Lateinisch Schenkung des Naturhistorischen Museums Luzern an die Kantonsbibliothek Luzern 1916 Verzeichnung=Description=Inventaire 27.03.1995 HAN-Katalogisierungsregeln pk Digitalisierung=Digitization=Numérisation TIFF 05.04.2015
A Three-Hybrid System to Probe In Vivo Protein-Protein Interactions: Application to the Essential Proteins of the RD1 Complex of M. tuberculosis
Creators: name: SACHIN SAMUCHIWAL
Publisher: name: figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Molecular Biology
subject: Biotechnology

description: p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 9.0px Helvetica} span.s1 {font: 9.5px Helvetica} Protein-protein interactions play a crucial role in enabling a pathogen to survive within a host. In many cases the interactions involve a complex of proteins rather than just two given proteins. This is especially true for pathogens like M. tuberculosis that are able to successfully survive the inhospitable environment of the macrophage. Studying such interactions in detail may help in developing small molecules that either disrupt or augment the interactions. Here, we describe the development of an E. coli based bacterial three-hybrid system that can be used effectively to study ternary protein complexes.
The protein-protein interactions involved in M. tuberculosis pathogenesis have been used
 as a model for the validation of the three-hybrid system. Using the M. tuberculosis RD1 encoded proteins CFP10, ESAT6 and Rv3871 for our proof-of-concept studies, we show that the interaction between the proteins CFP10 and Rv3871 is strengthened and stabilized in the presence of ESAT6, the known heterodimeric partner of CFP10. Isolating peptide candidates that can disrupt crucial protein-protein interactions is another application that the system offers. We demonstrate this by using CFP10 protein as a disruptor of a previously established interaction between ESAT6 and a small peptide HCL1; at the same time we also show that CFP10 is not able to disrupt the strong interaction between ESAT6 and another peptide SL3.
 The validation of the three-hybrid system paves the way for finding new peptides that are stronger binders of ESAT6 compared even to its natural partner CFP10. Additionally, we believe that the system offers an opportunity to study tri-protein complexes and also perform a screening of protein/peptide binders to known interacting proteins so as to elucidate novel tri-protein complexes.
title: Documenting research software in engineering science
Creators: name: Hermann, Sibylle
name: Fehr, Jörg
Publisher: name: Universität Stuttgart
Year: 2022
Subjects: subject: 020
subject: 620

description: The reuse of research software needs good documentation, however, the documentation in particular is often criticized. Especially in non-IT specific disciplines, the lack of documentation is attributed to the lack of training, the lack of time or missing rewards. This article addresses the hypothesis that scientists do document but do not know exactly what they need to document, why, and for whom. In order to evaluate the actual documentation practice of research software, we examined existing recommendations, and we evaluated their implementation in everyday practice using a concrete example from the engineering sciences and compared the findings with best practice examples. To get a broad overview of what documentation of research software entailed, we defined categories and used them to conduct the research. Our results show that the big picture of what documentation of research software means is missing. Recommendations do not consider the important role of researchers, who write research software, whose documentation takes mainly place in their research articles. Moreover, we show that research software always has a history that influences the documentation.
ВЕДЕНИЕ ЖЕНЩИН С ГИПЕРПЛАЗИЕЙ ЭНДОМЕТРИЯ В ЗАВИСИМОСТИ ОТ ГИСТОЛОГИЧЕСКОЙ СТРУКТУРЫ
Creators: name: Аскарова, Зебо
name: Рахимова, Амира
Publisher: name: Zenodo
Year: 2024

description: Гиперплазия эндометрия (ГЭ) представляет собой патологии слизистой оболочки матки, которая характеризуется аномальным увеличением количества клеток. Это состояние часто наблюдается у женщин в репродуктивном возрасте и значительно чаще у женщин в перименопаузе и постменопаузе. По статистике, распространенность гиперплазии эндометрия составляет 5-10% в общей популяции, тогда как у женщин с аномальными маточными кровотечениями этот показатель может достигать 20-50%. Важным аспектом в лечении является учитывание гистологической структуры гиперплазии, поскольку риск трансформации в рак эндометрия увеличивается при наличии атипической гиперплазии, которая имеет частоту около 3-10% среди всех случаев. Рассматриваются рекомендации по диагностике, включая УЗИ и гистероскопию с биопсией, а также методы лечения, которые могут включать гормональную терапию и хирургические вмешательства. В статье подчеркивается важность раннего выявления и индивидуализированного подхода к ведению женщин с гиперплазией эндометрия для снижения риска развития злокачественных процессов.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2020
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

284 pages (version 11.0).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).Version 8.1 released 4 October 2018 (one new paper added associated with v 8.0 entry; PDF bookmarks fixed).Version 8.2 released 7 October 2018 (expanded introduction associated with v 8.0 entry).Version 8.3 released 30 October 2018 (expanded introduction associated with v 8.0 entry; minor addition to earlier entries).Version 9.0 released 16 March 2019 (new entry).Version 10.0 released 7 April 2019 (new entry; minor update to previous entry).Version 11 released 31 March 2020 (two new entries; minor update to previous entry).
title: Are the EU Member States Still Sovereign States? The Perspective of International Law
Creators: name: Fassbender, Bardo
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2024
Subjects: subject: sovereignty
subject: independence
subject: autonomy
subject: United Nations Charter
subject: European sovereignty
subject: new legal order

description: European Papers - A Journal on Law and Integration, 2023 8(3), 1629-1643
description: I. The present meaning of State sovereignty. – II. The sovereignty of EU Member States. – III. Concluding remarks.
description: The present Article addresses the issue of the sovereignty of EU Member States from the perspective of general international law. In a first part, it tries to define the present meaning of sovereignty in international law. As a guide, three main approaches to sovereignty are used, i.e. an understanding of sovereignty as independence, as Völkerrechtsunmittelbarkeit (direct legal relationship between a State and international law), and as an autonomy of States under the constitution of the international community. In a second part, the Article applies the criteria of these three approaches to the Member States of the EU. It also addresses the question of whether the EU itself can be qualified as sovereign, and the issue of a “shared” or “divided” sovereignty in Europe. By way of conclusion, the third part makes a plea for defending the concept of supranationalism, as established in Europe after World War II, against the idea of State sovereignty.
PVC - Molecule of the Month June 2017 [Archived version]
Creators: name: Cotton, Simon
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for June 2017 about PVC. It is a pdf archive version of the HTML webpage.