cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Wnt/β-Catenin-Pathway Alterations and Homologous Recombination Deficiency in Cholangiocarcinoma Cell Lines and Clinical Samples: Towards Specific Vulnerabilities
Creators: name: Scheiter, Alexander
name: Hierl, Frederik
name: Winkel, Ingrid
name: Keil, Felix
name: Klier-Richter, Margit
name: Coulouarn, Cédric
name: Lüke, Florian
name: Kandulski, Arne
name: Evert, Matthias
name: Dietmaier, Wolfgang
name: Calvisi, Diego F.
name: Utpatel, Kirsten
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: INTRAHEPATIC CHOLANGIOCARCINOMA; BETA-CATENIN; PHASE-I; CANCER; MUTATIONS; OLAPARIB; TRANSCRIPTION; CHEMOTHERAPY; MECHANISMS; INHIBITOR; cholangiocarcinoma; beta-catenin; WNT; APC; HRD; Olaparib; PARP; intraductal papillary neoplasm of the bile duct
subject: 610 Medizin

description: Cholangiocarcinoma (CCA) features a dismal prognosis with limited treatment options. Genomic studies have unveiled several promising targets in this disease, including fibroblast growth factor receptor (FGFR) fusions and isocitrate dehydrogenase (IDH) mutations. To fully harness the potential of genomically informed therapies in CCA, it is necessary to thoroughly characterize the available model organisms, including cell lines. One parameter to investigate in CCA is homologous recombination deficiency (HRD). While mutations in homologous recombinational repair (HRR)-related genes have been detected, their predictive value remains undetermined. Using a targeted next-generation sequencing approach, we analyzed 12 human CCA cell lines and compared them to 62 CCA samples of the molecular tumor board cohort. The AmoyDx (R) HRD Focus Panel was employed to determine corresponding genomic scar scores (GSS). Ten of twelve cell lines harbored alterations in common HRR-related genes, and five cell lines were HRD-positive, although this parameter did not correlate well with Olaparib sensitivity. Moreover, functionally relevant APC and beta-catenin mutations were registered, which were also detected in 4/176 (2.3%) samples on a CCA microarray. Although rare, these alterations were exclusive to large duct type CCA with associated intraductal papillary neoplasms of the bile duct (IPNB) in 3 cases, pointing at a distinct form of cholangiocarcinogenesis with potential specific vulnerabilities.
Additional file 2 of Enhancing hospital protection measures reduces frontline medical workers’ stress during the pandemic
Creators: name: Xiaoxia, Zhou
name: Yan, Feng
name: Junwei, Wang
name: Bingyao, Zhang
name: Fei, Xu
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Supplementary Material 2.
Reithrodontomys (Aporodon) creper Bangs 1902
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Reithrodontomys
Reithrodontomys creper

description: Reithrodontomys (Aporodon) creper Bangs 1902
Reithrodontomys (Aporodon) creper Bangs 1902, Bull. Mus. Comp. Zool., 39: 39.
Type Locality: Panamá, Chiriquí Prov., Volcán de Chiriquí, 11,000 ft (3353 m).
Vernacular Names: Talamancan Harvest Mouse.
Distribution: Upper elevations, 1300-3350 m, in the Cordilleras Tilarán, Central, and Talamanca, Costa Rica, to Chiriquí region, W Panamá.
Conservation: IUCN – Lower Risk (lc).
Discussion: Subgenus Aporodon, tenuirostris species group. See Hopp and Rogers (1994, Mammalian Species, 482).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1081, DOI: 10.5281/zenodo.7316535
Multiparametric Ultrasound of Cervical Lymph Node Metastases in Head and Neck Cancer for Planning Non-Surgical Therapy
Creators: name: Künzel, Julian
name: Brandenstein, Moritz
name: Zeman, Florian
name: Symeou, Luisa
name: Platz Batista da Silva, Natascha
name: Jung, Ernst Michael
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: CONTRAST-ENHANCED ULTRASOUND; CLINICAL-PRACTICE RECOMMENDATIONS; TISSUE IMAGING QUANTIFICATION; SHEAR-WAVE ELASTOGRAPHY; DIFFERENTIAL-DIAGNOSIS; EFSUMB GUIDELINES; CEUS; BENIGN; DOPPLER; LIVER; CEUS; shear wave elastography; perfusion; neck metastases; superficial lymph nodes
subject: 610 Medizin

description: Background: We aimed to evaluate multiparametric ultrasound, to achieve a better understanding of the baseline characteristics of suspected cervical lymph node metastases in head and neck cancer before induction chemotherapy or chemoradiation. Methods: From February 2020 to April 2021, our complete ultrasound examination protocol was carried out on clinically evident malignant lymph nodes of histologically proven HNSCC in the pre-therapeutic setting. Results: A total of 13 patients were eligible for analysis. Using elastography, irregular clear hardening in areas in the center of the lymph node could be detected in all cases. Elastographic Q-analysis showed a significantly softer cortex compared to the center and surrounding tissue. The time-intensity curve analysis showed high values for the area under the curve and a short time-to-peak (fast wash-in) in all cases compared to the surrounding tissue. A parametric evaluation of contrast enhanced the ultrasound in the early arterial phase and showed an irregular enhancement from the margin in almost all investigated lymph nodes. These results show that the implementation of comprehensive, multiparametric ultrasound is suitable for classifying suspected lymph node metastasis more precisely than conventional ultrasound alone in the pre-therapeutic setting of HNSCC. Thus, these parameters may be used for improvements in the re-staging after chemoradiation or neoadjuvant therapy monitoring, respectively.
Additional file 3 of Enhancing hospital protection measures reduces frontline medical workers’ stress during the pandemic
Creators: name: Xiaoxia, Zhou
name: Yan, Feng
name: Junwei, Wang
name: Bingyao, Zhang
name: Fei, Xu
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Supplementary Material 3.
Schulz, Heinz-Manfred: Eine Gemeinde spricht über ihren Glauben
Creators: name: Aperdannier, Th.
Publisher: name: Ordenskorrespondenz
Year: 1970

description: Ordenskorrespondenz, Bd. 25 (1984): Ordenskorrespondenz: Zeitschrift für Fragen des Ordenslebens, Band 25
title: Rapport de voyage, Chantilly (1922) : Ligne de l'océan Indien, 1937, voyage n°10
Creators: name: Delaubier, Charles
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: Compagnie des Messageries Maritimes
subject: Transports maritimes - Histoire
subject: Marine marchande
subject: Journaux de bord

description: Chapitrage : Rapport du commandant - Rapport de mer
description: Source: French Lines & Compagnies, 1997 002 3993-04
description: Coverage: 1937-04-15/1937-06-20
Additional file 4 of Enhancing hospital protection measures reduces frontline medical workers’ stress during the pandemic
Creators: name: Xiaoxia, Zhou
name: Yan, Feng
name: Junwei, Wang
name: Bingyao, Zhang
name: Fei, Xu
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Supplementary Material 4.
Onthophagus (Onthophagiellus) millingeni d'Orbigny 1898
Creators: name: Ziani, Stefano
name: Abdel-Dayem, Mahmoud Saleh
name: Aldhafer, Hathal Mohammed
name: Barbero, Enrico
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Onthophagus
Onthophagus millingeni

description: Onthophagus (Onthophagiellus) millingeni d’Orbigny, 1898
[Fig. 15]
Literature quotes. SAUDI ARABIA: Hejaz, “Hedjaz” (d’Orbigny 1898a). YEMEN: without locality (d’Orbigny 1898a).
Material examined. SAUDI ARABIA: Asir Province, Abha, Raydah Nature Reserve, 1614 m (1811.749′N 4223.345′E), 31.vii.2015, H. Al Dhafer, H. Fadl, M. Abdel-Dayem, A. El Gharbawy & A. El Torkey leg. 2 exx. (KSMA); ibidem, 17.xi.2015, VC, H. Al Dhafer, H. Fadl, M. Abdel-Dayem, A. El Gharbawy & A. El Torkey leg. 1 ex. (KSMA); ibidem, 1851 m (1811.679′N 4223.691′E), H. Al Dhafer, H. Fadl, M. Abdel-Dayem, A. El Torkey & A. El Gharbawy leg. 1 ex. (KSMA); ibidem, 1897 m (1811.695′N 4223.818′E), 26.iv.2014, H. Al Dhafer, H. Fadl, M. Abdel-Dayem, A. El Torkey & A. El Gharbawy leg. 1 ex. (KSMA); ibidem, 9.v.2015, PT. H. Al Dhafer, et al. leg. 1 ♀ (KSMA); ibidem, 31.vii.2015, Al Dhafer, H. Fadl, M. Abdel-Dayem, A. El Gharbawy & A. El Torkey leg. 1 ex. (KSMA). YEMEN: Sana’a Governorate, Bait Bows dam, 2500 m (1516′N 4412′E), V. Hula & Niedobov leg. 1 ex. (NMPC); Haddah, 2413 m (1517′24″N 4409′59″), 11/ 20.xi.2003, D. Král leg. 2 exx. (NMPC); Jabal Haraz mts. S of Manakhah vill., 2510 m (1504′N 4345′E), 3.xi.2010, J. Hájek & Bezdĕk leg. 15 exx. (NMPC); Wadi Dhahr, 10.vi.2009, V. Hula leg 1 ex. (NMPC).
Distribution. Arabian Peninsula: Saudi Arabia, Yemen (d’Orbigny 1898a). Asia: Iraq (Ziani & Bezděk 2016).
Remarks. According to Palestrini (1982) O. millingeni belongs to the subgenus Onthophagiellus Balthasar, 1935. As noted by Zunino (1976), Boucomont & Gillet (1927) misunderstood d’Orbigny (1913) and wrongly considered Onthophagus millingeni a junior synonym of O. tessulatus Harold, 1871, a species distributed in Eritrea, Ethiopia and Somalia. Subsequent authors such as Winkler (1929), Balthasar (1963), Ferreira (1972) and Paulian (1980) uncritically followed this synonymy. Actually the two species, even if very close, can be mainly distinguished by the morphology of genital armatures (Zunino 1976). All the Arabian records for O. tessulatus are to be attributed to O. millingeni that is therefore an Iraqi-Arabian endemic.
description: Published as part of Ziani, Stefano, Abdel-Dayem, Mahmoud Saleh, Aldhafer, Hathal Mohammed & Barbero, Enrico, 2019, An overview of the Onthophagini from the Arabian Peninsula (Coleoptera: Scarabaeoidea: Scarabaeidae), pp. 1-36 in Zootaxa 4658 (1) on page 21, DOI: 10.11646/zootaxa.4658.1.1, http://zenodo.org/record/3373040
“For me, it's just a piece of freedom”—Increased empowerment through physical activity promotion among socially disadvantaged women
Creators: name: Sauter, Alexandra
name: Herbert-Maul, Annika
name: Abu-Omar, Karim
name: Thiel, Ansgar
name: Ziemainz, Heiko
name: Frahsa, Annika
name: Linder, Stephanie
name: Herrmann-Johns, Anne
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: DIFFICULT LIFE SITUATIONS; HEALTH-PROMOTION; PARTICIPATION; PREVENTION; OUTCOMES; PROGRAM; physical activity; empowerment; community-based participatory research; women's health; low socioeconomic status; ethnic minority; qualitative research; health promotion
subject: 610 Medizin

description: IntroductionCommunity-based participatory research (CBPR) is an effective health promotion approach for reaching socially disadvantaged groups. However, there is limited evidence on how such interventions and their effects can be reproduced across time and place. The present study examines the effects of BIG (i.e., movement as an investment in health), a long-standing German CBPR project. Since 2005, BIG has aimed to empower women in difficult life situations to increase control over their health determinants and reduce social inequalities by promoting physical activity. One of BIG's key features is its implementation in several German municipalities since 2005. This study explores (a) whether participation could change women's empowerment, and (b) how increased empowerment affects other areas of women's lives. MethodsWith a total of 63 interviewees (i.e., 40 participating women, 7 trainers, 3 project coordinators, and 13 stakeholders), we conducted 53 semi-structured qualitative interviews in five BIG communities between 2007 and 2011. Some interviews were conducted with two people simultaneously. The interview guide contained questions on various dimensions of empowerment (e.g., project engagement, increased self-efficacy, and developed competencies). Framework analysis was used for the analytical process. ResultsBIG contributed to women's empowerment in various ways, including increased self-efficacy, social network promotion, competency development, and increased motivation to change physical activity behavior. Women who took on added tasks and became more involved in project planning also strengthened their organizational empowerment. Furthermore, increased empowerment had a positive influence on the women's quality of life, family, and professional lives. ConclusionThe novel findings helped in understanding the effects of a complex empowerment-based approach that promoted physical activity among women in difficult life situations. Future research should focus on the long-term effects of these programs and their transferability to other sites. Further effort is necessary in the area of public health policy.
Schwarz, Heino: Katholisch, proletarisch und in der Einheitsgewerkschaft
Creators: name: Ossenbühl, K.H.
Publisher: name: Ordenskorrespondenz
Year: 1970

description: Ordenskorrespondenz, Bd. 25 (1984): Ordenskorrespondenz: Zeitschrift für Fragen des Ordenslebens, Band 25
title: Activité du port de Saint-Malo – 1686 – Bordeaux
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: dopants
subject: produits manufacturés
subject: produits de la mer
subject: poissons
subject: produits agroalimentaires
subject: alcool
subject: fruits et légumes
subject: épices et condiments
subject: matériaux de construction
subject: textiles
subject: graines
subject: produits exotiques et ultramarins

description: Marchandises au départ de Saint-Malo : savon ; morues
description: Catégories de marchandises au départ de Saint-Malo : produits manufacturés ; produits de la mer ; poissons
description: Marchandises arrivées à Saint-Malo : vin ; eau de vie ; prunes ; vinaigre ; résine ; avirons ; couvertures de laine ; graines de lin ; tabac ; sucre
description: Catégories de marchandises arrivées à Saint-Malo : produits agroalimentaires ; alcool ; fruits et légumes ; épices et condiments ; matériaux de construction ; produits manufacturés ; textiles ; graines ; produits exotiques et ultramarins ; dopants
description: Cette fiche est issue de l’enquête menée par Jean Delumeau sur l’activité du port de Saint-Malo au 17e et 18e siècle. Cette fiche correspond à l’activité de l’année 1686 avec le port "Bordeaux"
description: Coverage: Grand cabotage
description: Bibliographic citation: LE CORRE, Annick. L'Activité maritime de Saint-Malo en 1686 et 1687. DES : Histoire : Rennes, 1958 (Bibliothèque François-Lebrun - Rennes 2, MH 1003)
description: date: Date de numérisation : 2021 à 2023
description: created: Années 1950-1960
Hereditary Diffuse Gastric Cancer: Molecular Genetics, Biological Mechanisms and Current Therapeutic Approaches
Creators: name: Cosma, Lidia-Sabina
name: Schlosser, Sophie
name: Tews, Hauke C.
name: Müller, Martina
name: Kandulski, Arne
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: hereditary diffuse gastric cancer (HDGC); CDH1 germline mutation; CTNNA1 mutation; molecular genetics
subject: 610 Medizin

description: Hereditary diffuse gastric cancer is an autosomal dominant syndrome characterized by a high prevalence of diffuse gastric cancer and lobular breast cancer. It is caused by inactivating mutations in the tumor suppressor gene CDH1. Genetic testing technologies have become more efficient over the years, also enabling the discovery of other susceptibility genes for gastric cancer, such as CTNNA1 among the most important genes. The diagnosis of pathogenic variant carriers with an increased risk of developing gastric cancer is a selection process involving a multidisciplinary team. To achieve optimal long-term results, it requires shared decision-making in risk management. In this review, we present a synopsis of the molecular changes and current therapeutic approaches in HDGC based on the current literature.
Onthophagus (Onthophagus) falsus Gillet 1925
Creators: name: Ziani, Stefano
name: Abdel-Dayem, Mahmoud Saleh
name: Aldhafer, Hathal Mohammed
name: Barbero, Enrico
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Onthophagus
Onthophagus falsus

description: Onthophagus (Onthophagus) falsus Gillet, 1925
[Fig. 16]
Literature quotes. None.
Material examined. SAUDI ARABIA: Riyadh Province, Al-Wasiel, 19.xi. 205, SW on Alfalfa, M. Ur Rehman leg. 1 ♂ (KSMA); Wadi Al Dawaser, Al Muhmmadiya Farm, 700 m (2025.497′N 4443.563′E), 9.v.2018, H. Al Dhafer et al. leg. 2 ♂♂ (KSMA); Wadi Hanifa, 14.xi.2015, HP in date palm, E.M. Khan leg. 2 ♂♂ (KSMA).
Distribution. Asia: Afghanistan (Balthasar 1963), central and northern India (Arrow 1931; Mittal & Jain 2015), south-western India (Sabu et al., 2011; Venugopal et al., 2012); Pakistan (Arrow 1931).
Remarks. First record for the Arabian Peninsula, notably Saudi Arabia. The taxon was placed in the subgenus Gibbonthophagus Balathasar, 1935 by Kabakov (2006), then in Onthophagus species incertae sedis by Ziani & Bezděk (2016). We have herein inserted O. falsus in the nominotypical subgenus because, in our opinion, the species is phylogenetically more closely related to Onthophagus taurus (Schreber, 1759), the type species of the subgenus, than to any type species of any other genus or subgenus of Onthophagini. Paramera apex and lamella copulatrix support this placement.
description: Published as part of Ziani, Stefano, Abdel-Dayem, Mahmoud Saleh, Aldhafer, Hathal Mohammed & Barbero, Enrico, 2019, An overview of the Onthophagini from the Arabian Peninsula (Coleoptera: Scarabaeoidea: Scarabaeidae), pp. 1-36 in Zootaxa 4658 (1) on page 22, DOI: 10.11646/zootaxa.4658.1.1, http://zenodo.org/record/3373040
title: Lettre n°868 de Paul d'Estournelles de Constant à Nicholas Murray Butler (5 juillet 1921)
title: Letter number 868 from Paul d'Estournelles de Constant to Nicholas Murray Butler (July 5, 1921)
Creators: name: d'Estournelles de Constant, Paul
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Pacifisme
Guerre mondiale (1914-1918)

description: Source: Archives de la Sarthe – France
Reithrodontomys (Aporodon) darienensis Pearson 1939
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Reithrodontomys
Reithrodontomys darienensis

description: Reithrodontomys (Aporodon) darienensis Pearson 1939
Reithrodontomys (Aporodon) darienensis Pearson 1939, Not. Naturae, Acad. Nat. Sci. Philadelphia, 6: 1.
Type Locality: Panamá, Darién Prov., Santa Cruz de Cana, upper Río Tuyra, 2000 ft (610 m).
Vernacular Names: Darien Harvest Mouse.
Distribution: E Panamá, including Azuero Peninsula, and perhaps adjacent Colombia.
Conservation: IUCN – Lower Risk (lc).
Discussion: Subgenus Aporodon, mexicanus species group. Hooper (1952) viewed R. darienensis as closely related to R. gracilis.
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1081, DOI: 10.5281/zenodo.7316535
DSCAM-AS1 Long Non-Coding RNA Exerts Oncogenic Functions in Endometrial Adenocarcinoma via Activation of a Tumor-Promoting Transcriptome Profile
Creators: name: Treeck, Oliver
name: Weber, Florian
name: Fritsch, Juergen
name: Skrzypczak, Maciej
name: Schüler-Toprak, Susanne
name: Buechler, Christa
name: Ortmann, Olaf
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: CELL LUNG-CANCER; HEPATOCELLULAR-CARCINOMA; EXPRESSION; LNCRNA; PROLIFERATION; PROGRESSION; PROGNOSIS; INTERACTS; ROLES; WNT7A; endometrial adenocarcinoma; long non-coding RNA; DSCAM-AS1; transcriptome
subject: 610 Medizin

description: Accumulating evidence suggests that lncRNA DSCAM-AS1 acts tumor-promoting in various cancer entities. In breast cancer, DSCAM-AS1 was shown to be the lncRNA being most responsive to induction by estrogen receptor alpha (ER alpha). In this study, we examined the function of DSCAM-AS1 in endometrial adenocarcinoma using in silico and different in vitro approaches. Initial analysis of open-source data revealed DSCAM-AS1 overexpression in endometrial cancer (EC) (p < 0.01) and a significant association with shorter overall survival of EC patients (HR = 1.78, p < 0.01). In EC, DSCAM-AS1 was associated with endometrial tumor promotor gene PRL and with expression of ERoc and its target genes TFF1 and PGR. Silencing of this lncRNA by RNAi in two EC cell lines was more efficient in ER alpha-negative HEC-1B cells and reduced their growth and the expression of proliferation activators like NOTCH1, PTK2 and EGR1. DSCAM-AS1 knockdown triggered an anti-tumoral transcriptome response as revealed by Affymetrix microarray analysis, emerging from down-regulation of tumor-promoting genes and induction of tumor-suppressive networks. Finally, several genes regulated upon DSCAM-AS1 silencing in vitro were found to be inversely correlated with this lncRNA in EC tissues. This study clearly suggests an oncogenic function of DSCAM-AS1 in endometrial adenocarcinoma via activation of a tumor-promoting transcriptome profile.
Onthophagus (Palaeonthophagus) aerarius Reitter 1892
Creators: name: Ziani, Stefano
name: Abdel-Dayem, Mahmoud Saleh
name: Aldhafer, Hathal Mohammed
name: Barbero, Enrico
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Onthophagus
Onthophagus aerarius

description: Onthophagus (Palaeonthophagus) aerarius Reitter, 1892
Literature quotes. SAUDI ARABIA: “Nord-ouest de l’Arabie: Ouady-Jeten” [locality not found] (d’Orbigny 1913a). Tabuk Province, Hism (Ziani & Gudenzi 2009).
Material examined. SAUDI ARABIA: Tabuk Province, “Hismé” (MNHN).
Distribution. Arabian Peninsula: Saudi Arabia (d’Orbigny 1913a). North Africa: Algeria, Egypt, Lybia, Morocco, Tunisia (Ziani & Bezděk 2016). Asia: Israel, Jordan, Palestine, Syria, (Ziani & Gudenzi 2009). Europe: Azerbaijan, Armenia (Ziani & Gudenzi 2009).
description: Published as part of Ziani, Stefano, Abdel-Dayem, Mahmoud Saleh, Aldhafer, Hathal Mohammed & Barbero, Enrico, 2019, An overview of the Onthophagini from the Arabian Peninsula (Coleoptera: Scarabaeoidea: Scarabaeidae), pp. 1-36 in Zootaxa 4658 (1) on page 22, DOI: 10.11646/zootaxa.4658.1.1, http://zenodo.org/record/3373040
Observations on Turner 1977
Creators: name: Marichal, Robert
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015

description: vue 38
description: Annotations on E. G. TURNER, The tipology of the early codex, Philadelphia 1977.
description: Source: 4MAR_4_1.11-2
description: created: n. d.
Additional file 5 of Enhancing hospital protection measures reduces frontline medical workers’ stress during the pandemic
Creators: name: Xiaoxia, Zhou
name: Yan, Feng
name: Junwei, Wang
name: Bingyao, Zhang
name: Fei, Xu
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Supplementary Material 5.
Diseño y comparación de metodologías experimentales para ablandamiento de dureza total en el tratamiento de agua potable
Creators: name: Santana Parra, Fabiana Esther
name: Pichot Pardo, Laura Daniela
Publisher: name: Zenodo
Year: 2024

description: La dureza del agua, causada por sulfato de calcio (CaSO₄) y sulfato de magnesio (MgSO₄), representa un desafío ambiental y operativo al obstruir sistemas hidráulicos y afectar la calidad del agua. Este estudio compara dos métodos para reducir la dureza: filtración con zeolita y un proceso químico de cal-soda. Se trabajó con tres muestras sintéticas de dureza de 73.33, 100 y 210 mg/L CaCO3. El método con zeolita logró una remoción máxima del 72,8% en agua con alta dureza, condicionado al estado de la zeolita y el ajuste del pH. Por otro lado, el tratamiento de dureza por precipitación química con cal-soda alcanzó hasta un 66% de eficiencia, esta remoción máxima se observó bajo condiciones de mezcla medias y concentración de agua moderadamente dura. Ambos métodos demostraron ser eficaces, destacando la importancia de controlar parámetros como pH y tiempo de reacción. De modo que este trabajo ofrece soluciones prácticas para disminuir la dureza del agua, con aplicaciones potenciales en el tratamiento de agua potable en sistemas industriales y domésticos.
Mitrapsylla repens Burckhardt & Queiroz
Creators: name: Rendón-Mera, Diana Isabel
name: Burckhardt, Daniel
name: Cavichioli, Rodney R.
name: Queiroz, Dalva L.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Psyllidae
Mitrapsylla
Mitrapsylla repens

description: Mitrapsylla repens Burckhardt & Queiroz
LSID: urn:lsid:zoobank.org:act: 6BE88B10-5EC0-4BD4-B733-9ACCCD68E5BD
Mitrapsylla repens Burckhardt & Queiroz, 2020: 48. Holotype ♁, Brazil: Paraná, Tibagi, Jardim Botânico, Parque Guartelá, -24.5595, -50.2565, 930 m, 9.vii.2013, vegetaç„o de Cerrado (D.L. Queiroz), #525(MZSP, dry) (examined).
Description of adult and immature by Burckhardt & Queiroz (2020).
Distribution. Brazil (Minas Gerais, Paraná) (Burckhardt & Queiroz 2020).
Host-plant. Adults were collected on Copaifera langsdorffii Desf. (Leguminosae, Detarioideae, Detarieae) which is a likely host.
description: Published as part of Rendón-Mera, Diana Isabel, Burckhardt, Daniel, Cavichioli, Rodney R. & Queiroz, Dalva L., 2020, Taxonomy and host-plant relationships of the psyllid genus Mitrapsylla (Hemiptera: Psylloidea: Psyllidae) in Brazil, pp. 1-100 in Zootaxa 4887 (1) on page 85, DOI: 10.11646/zootaxa.4887.1.1, http://zenodo.org/record/4297565
title: Lettre n°761 de Paul d'Estournelles de Constant à Nicholas Murray Butler (31 décembre 1920)
title: Letter number 761 from Paul d'Estournelles de Constant to Nicholas Murray Butler (December 31, 1920)
Creators: name: d'Estournelles de Constant, Paul
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Pacifisme
Guerre mondiale (1914-1918)

description: Source: Archives de la Sarthe – France
Workplace Violence and Aggression in Hospital Inpatient Settings from the Perspective of Nurses and Midwives in Regional Australia
Creators: name: Tyler, Vanessa
Publisher: name: Southern Cross University
Year: 2023

description: Health professionals in hospital inpatient settings are exposed to workplace violence and aggression (WPVA). Nurses experience more WPVA than any other healthcare profession. Studies have explored WPVA predominately in the emergency department, mental health and aged care. This study aimed to explore WPVA in hospital inpatient settings from the perspective of nurses and midwives.
description: This research included an integrative review and the pilot and psychometric evaluation of a WPVA Perception Scale using a cross-sectional survey of nurses and midwives employed in hospital inpatient settings across a regional local health district. A social-ecological theoretical framework underpinned the study.
description: The results of the published integrative review identified that organisational culture, including accepting violence as part of the job, and the type of violence were key factors influencing reporting. Consistent messaging on policy compliance and education programs may improve the organisational culture around reporting WPVA. Educating the workforce to define and understand the nature of WPVA is also required.
description: The psychometric properties of the WPVA scale were examined and subjected to exploratory factor analysis producing a 13-item WPVA Perception Scale consisting of two constructs ‘leadership and support strategies’ (10 items) and ‘staff attitudes and behaviours’ (3 items).
description: There was no significant overall association between years of experience and nurses and midwives’ perception of WPVA. However, there was a significant association between place of work and perceptions of ‘leadership and support strategies’, ‘staff attitudes and behaviours’ and overall perception of WPVA.
description: This thesis identifies six key findings: 1) nurses’ and midwives’ perceptions of WPVA are indicators of safety culture; 2) nurses and midwives are frequently exposed to WPVA; 3) there is a need to develop a validated WPVA Perception Scale; 4) the WPVA Perception Scale can inform safety culture education; 5) nurses’ and midwives’ experience are not associated with vulnerability to WPVA; and 6) nurses’ and midwives’ perceptions of WPVA differ based on workplace location and role.
description: It is envisaged that the results of this thesis will inform a safety culture program that can be used to address WPVA in hospital inpatient settings in regional Australia. This thesis demonstrates how different approaches are required at unit/ward and hospital/organisational levels based on existing leadership and support strategies, and staff attitude and behaviour. Future research could explore WPVA in other disciplines and settings, such as metropolitan Australia, international locations and specifically in community health, mental health, alcohol and other drugs services.
title: Markov Chain Monte Carlo for Continuous-Time Switching Dynamical Systems
Creators: name: Köhs, Lukas
name: Alt, Bastian
name: Koeppl, Heinz
Publisher: name: PMLR
Year: 2025

description: Switching dynamical systems are an expressive model class for the analysis of time-series data. As in many fields within the natural and engineering sciences, the systems under study typically evolve continuously in time, it is natural to consider continuous-time model formulations consisting of switching stochastic differential equations governed by an underlying Markov jump process. Inference in these types of models is however notoriously difficult, and tractable computational schemes are rare. In this work, we propose a novel inference algorithm utilizing a Markov Chain Monte Carlo approach. The presented Gibbs sampler allows to efficiently obtain samples from the exact continuous-time posterior processes. Our framework naturally enables Bayesian parameter estimation, and we also include an estimate for the diffusion covariance, which is oftentimes assumed fixed in stochastic differential equations models. We evaluate our framework under the modeling assumption and compare it against an existing variational inference approach.
Deep Learning-Based Image Analysis for the Quantification of Tumor-Induced Angiogenesis in the 3D In Vivo Tumor Model—Establishment and Addition to Laser Speckle Contrast Imaging (LSCI)
Creators: name: Kuri, Paulina Mena
name: Pion, Eric
name: Mahl, Lina
name: Kainz, Philipp
name: Schwarz, Siegfried
name: Brochhausen, Christoph
name: Aung, Thiha
name: Haerteis, Silke
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: CHICK CHORIOALLANTOIC MEMBRANE; CAM ASSAY; CANCER; ANGIOSARCOMA; CELLS; EXPRESSION; INVASION; OUTCOMES; GROWTH; 3D in vivo tumor model; chorioallantoic membrane (CAM); angiogenesis; tumor; laser speckle contrast imaging; image analysis software; CAM assay application; artificial intelligence; deep learning; blood circulation
subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: (1) Background: angiogenesis plays an important role in the growth and metastasis of tumors. We established the CAM assay application, an image analysis software of the IKOSA platform by KML Vision, for the quantification of blood vessels with the in ovo chorioallantoic membrane (CAM) model. We added this proprietary deep learning algorithm to the already established laser speckle contrast imaging (LSCI). (2) Methods: angiosarcoma cell line tumors were grafted onto the CAM. Angiogenesis was measured at the beginning and at the end of tumor growth with both measurement methods. The CAM assay application was trained to enable the recognition of in ovo CAM vessels. Histological stains of the tissue were performed and gluconate, an anti-angiogenic substance, was applied to the tumors. (3) Results: the angiosarcoma cells formed tumors on the CAM that appeared to stay vital and proliferated. An increase in perfusion was observed using both methods. The CAM assay application was successfully established in the in ovo CAM model and anti-angiogenic effects of gluconate were observed. (4) Conclusions: the CAM assay application appears to be a useful method for the quantification of angiogenesis in the CAM model and gluconate could be a potential treatment of angiosarcomas. Both aspects should be evaluated in further research.
Reithrodontomys (Reithrodontomys) fulvescens J. A. Allen 1894
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Reithrodontomys
Reithrodontomys fulvescens

description: Reithrodontomys (Reithrodontomys) fulvescens J. A. Allen 1894
Reithrodontomys (Reithrodontomys) fulvescens J. A. Allen 1894, Bull. Am. Mus. Nat. Hist., 6: 319.
Type Locality: México, Sonora, Oposura, 2000 ft (610 m).
Vernacular Names: Fulvous Harvest Mouse.
Synonyms: Reithrodontomys (Reithrodontomys) amoenus (Eliot 1905); Reithrodontomys (Reithrodontomys) aurantius J. A. Allen 1895; Reithrodontomys (Reithrodontomys) canus Benson 1939; Reithrodontomys (Reithrodontomys) chiapensis A. H. Howell 1914; Reithrodontomys (Reithrodontomys) chrysotis Elliot 1899; Reithrodontomys (Reithrodontomys) difficilis Merriam 1901; Reithrodontomys (Reithrodontomys) griseoflavus Merriam 1901; Reithrodontomys (Reithrodontomys) helvolus Merriam 1901; Reithrodontomys (Reithrodontomys) inexspectatus Elliot 1903; Reithrodontomys (Reithrodontomys) infernatis Hooper 1950; Reithrodontomys (Reithrodontomys) intermedius J. A. Allen 1895; Reithrodontomys (Reithrodontomys) laceyi J. A. Allen 1896; Reithrodontomys (Reithrodontomys) meridionalis Anderson and Jones 1960; Reithrodontomys (Reithrodontomys) mustelinus A. H. Howell 1914; Reithrodontomys (Reithrodontomys) nelsoni A. H. Howell 1914; Reithrodontomys (Reithrodontomys) tenuis J. A. Allen 1899; Reithrodontomys (Reithrodontomys) toltecus Merriam 1901; Reithrodontomys (Reithrodontomys) tropicalis Davis 1944.
Distribution: SC Arizona, NC, S and E Texas, to SW Missouri and W Mississippi, USA; south through much of México, to W Nicaragua; excluding Yucatán Peninsula and Caribbean coastal lowlands.
Conservation: IUCN – Lower Risk (lc).
Discussion: Subgenus Reithrodontomys, fulvescens species group. Chromosomal complement (2n = 50) interpreted as primitive for the genus (Robbins and Baker, 1980). Genetically strongly divergent from six other species of the subgenus Reithrodontomys based on cytochrome b sequences (Bell et al., 2001). Westerly dispersion along grassy railway borders onto Llano Estacado, NC Texas, documented by Yancey and Jones (1997); also see Peppers et al. (1998) for records of northward extension in Texas. Appreciable fixed allelic differences detected among certain samples from the US and Mexico advise the need for taxonomic review of included synonyms (Arellano et al., 2003; Arnold et al., 1983). See Spencer and Cameron (1982, Mammalian Species, 174).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1081, DOI: 10.5281/zenodo.7316535
Endoplasmic Reticulum Stress Induces Senescence in Human Lung Fibroblasts
Creators: name: Koloko Ngassie, Maunick Lefin
name: Drake, Li
name: Roos, Benjamin B.
name: Koenig-Kappes, Amanda
name: Pabelick, Christina M.
name: Gosens, Reinoud
name: Brandsma, Corry-Anke
name: Burgess, Janette K.
name: Prakash, Y.S.
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310103
subject: Cell metabolism
classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310102
subject: Cell development, proliferation and death

description: Supplementary file 1: mRNA levels of senescence markers, ER chaperones and extracellular matrix (ECM) proteins in MG132-treated lung fibroblasts at timepoint 8 daysSupplementary file 2: Expression of ER stress, senescence markers and ECM proteins in lysates from MG132-treated young and old human lung fibroblastsSupplementary file 3: Examples of "blots" from the capillary WES showing the specificity of the used antibodies targeting the selected ER stress, senescence, anti-apoptotic markers and ECM proteins
Onthophagus (Palaeonthophagus) nebulosus Reiche 1864
Creators: name: Ziani, Stefano
name: Abdel-Dayem, Mahmoud Saleh
name: Aldhafer, Hathal Mohammed
name: Barbero, Enrico
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Onthophagus
Onthophagus nebulosus

description: [Onthophagus (Palaeonthophagus) nebulosus Reiche, 1864]
Literature quotes. SAUDI ARABIA: Makkah Province, Djedda (d’Orbigny 1898c). YEMEN: without locality (d’Orbigny 1898c).
Material examined. None.
Distribution. Arabian Peninsula: Saudi Arabia and Yemen (d’Orbigny 1898c). North Africa: Algeria, Egypt, Lybia, Morocco, Tunisia (Baraud 1985). Asia: Jordan, Israel, Syria, Iraq, Iran (Ziani & Bezděk 2016).
Remarks. The presence of the species in Saudi Arabia and particularly in Yemen requires confirmation.
description: Published as part of Ziani, Stefano, Abdel-Dayem, Mahmoud Saleh, Aldhafer, Hathal Mohammed & Barbero, Enrico, 2019, An overview of the Onthophagini from the Arabian Peninsula (Coleoptera: Scarabaeoidea: Scarabaeidae), pp. 1-36 in Zootaxa 4658 (1) on page 22, DOI: 10.11646/zootaxa.4658.1.1, http://zenodo.org/record/3373040
The epidemiology and direct healthcare costs of aseptic nonunions in Germany – a descriptive report
Creators: name: Walter, Nike
name: Hierl, Katja
name: Brochhausen, Christoph
name: Alt, Volker
name: Rupp, Markus
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: FRACTURE; MANAGEMENT; ECONOMICS; UNION; Epidemiology; Nonunion; Direct healthcare costs
subject: 610 Medizin

description: Aims This observational cross-sectional study aimed to answer the following questions: 1) how has nonunion incidence developed from 2009 to 2019 in a nationwide cohort; 2) what is the age and sex distribution of nonunions for distinct anatomical nonunion localizations; and 3) how high were the costs for surgical nonunion treatment in a level 1 trauma centre in Germany? Methods Data consisting of annual International Classification of Diseases (ICD)- 10 diagnosis codes from German medical institutions from 2009 to 2019, provided by the Federal Statistical Office of Germany (Destatis), were analyzed. Nonunion incidence was calculated for anatom-ical localization, sex, and age groups. Incidence rate ratios (IRRs) were determined and com-pared with a two-sample z -test. Diagnosis-related group (DRG)-reimbursement and length of hospital stay were retrospectively retrieved for each anatomical localization, considering 210 patients. Results In 2019, a total of 11,840 nonunion cases (17.4/100,000 inhabitants) were treated. In com-parison to 2018, the incidence of nonunion increased by 3% (IRR 1.03, 95% confidence in-terval (CI) 0.53 to 1.99, p = 0.935). The incidence was higher for male cases (IRR female/ male: 0.79, 95% CI 0.76 to 0.82, p = 0.484). Most nonunions occurred at the pelvic and hip region (3.6/100,000 inhabitants, 95% CI 3.5 to 3.8), followed by the ankle and foot as well as the hand (2.9/100,000 inhabitants each). Mean estimated DRG reimbursement for in-hospital treatment of nonunions was highest for nonunions at the pelvic and hip region ( euro 8,319 (SD 2,410), p < 0.001). Conclusion Despite attempts to improve fracture treatment in recent years, nonunions remain a problem for orthopaedic and trauma surgery, with a stable incidence throughout the last decade.
Treatment of Secondary Aortoenteric Fistulas Following AORTIC Aneurysm Repair in a Tertiary Reference Center
Creators: name: Oikonomou, Kyriakos
name: Pfister, Karin
name: Kasprzak, Piotr M.
name: Schierling, Wilma
name: Betz, Thomas
name: Sachsamanis, Georgios
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: ; aortoenteric; aortointestinal; fistula; endovascular aneurysm repair; abdominal aortic aneurysm
subject: 610 Medizin

description: Objectives: To present our experience with various therapeutic approaches for the treatment of secondary aortoenteric fistulas following open and endovascular aortic aneurysm repair. Methods and Materials: A retrospective data analysis of patients treated for secondary aortoenteric fistulas in a single vascular institution between January 2005 and December 2018 was performed. Analyzed parameters included patients' demographics, clinical presentation, diagnostic work-up, perioperative data and repair durability during follow-up. Results: Twenty-three patients with aortoenteric fistulas were treated in the target period. The fistulous connection was located in 21 cases (91.3%) in the duodenum and in two cases (8.7%) in the small intestine. Average time between the initial procedure and detection of the aortoenteric fistula was 69.4 +/- 72.5 months. The most common presenting symptom was gastrointestinal bleeding (n = 12, 52.2%), followed by symptoms suggestive of chronic infection (n = 11, 47.8%). Open surgical repair was performed in 19 patients (bridging in 3 patients), and endovascular repair was carried out in two cases and one patient underwent a hybrid operation. One patient underwent abscess drainage due to significant comorbidities. Mean follow-up was 35.1 +/- 35.5 months. In-hospital mortality and overall mortality were 43.5% (10/23) and 65.2% (15/23), respectively. Patients presenting with bleeding had a significantly higher perioperative mortality rate in comparison to patients presenting with chronic infection (66.7% (8/12) and 18.2% (2/11), respectively, p = 0.019). Patients who underwent stent-graft implantation for control of acute life-threatening bleeding showed significantly better perioperative survival in comparison to patients that were acutely treated with an open procedure (66.6%, (4/6) and 0% (0/6), respectively, p = 0.014). Perioperative mortality was also higher for ASA IV patients (71.4%, 5/7), when compared to ASA III Patients (31.2%, 5/16), although this did not reach statistical significance (p = 0.074). Conclusion: Treatment of secondary aortoenteric fistulas is associated with a high perioperative mortality rate. Patients who survive the perioperative period following open surgical repair in the absence of hemorrhagic shock show acceptable midterm results during follow-up. Stent-graft implantation for bleeding control in patients presenting with life-threatening bleeding seems to be associated with lower perioperative mortality rates.
Additional file 7 of Enhancing hospital protection measures reduces frontline medical workers’ stress during the pandemic
Creators: name: Xiaoxia, Zhou
name: Yan, Feng
name: Junwei, Wang
name: Bingyao, Zhang
name: Fei, Xu
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Supplementary Material 7.
Self-organized criticality as a framework for consciousness: A review study
Creators: name: Walter, Nike
name: Hinterberger, Thilo
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: self-organized criticality (theory), neurodynamical model, theories of consciousness, complexity, phase transition
subject: 610 Medizin

description: Objective: 
No current model of consciousness is univocally accepted on either theoretical or empirical grounds, and the need for a solid unifying framework is evident. Special attention has been given to the premise that self-organized criticality (SOC) is a fundamental property of neural system. SOC provides a competitive model to describe the physical mechanisms underlying spontaneous brain activity, and thus, critical dynamics were proposed as general gauges of information processing representing a strong candidate for a surrogate measure of consciousness. As SOC could be a neurodynamical framework, which may be able to bring together existing theories and experimental evidence, the purpose of this work was to provide a comprehensive overview of progress of research on SOC in association with consciousness.
Methods: 
A comprehensive search of publications on consciousness and SOC published between 1998 and 2021 was conducted. The Web of Science database was searched, and annual number of publications and citations, type of articles, and applied methods were determined.
Results: 
A total of 71 publications were identified. The annual number of citations steadily increased over the years. Original articles comprised 50.7% and reviews/theoretical articles 43.6%. Sixteen studies reported on human data and in seven studies data were recorded in animals. Computational models were utilized in n = 12 studies. EcoG data were assessed in n = 4 articles, fMRI in n = 4 studies, and EEG/MEG in n = 10 studies. Notably, different analytical tools were applied in the EEG/MEG studies to assess a surrogate measure of criticality such as the detrended fluctuation analysis, the pair correlation function, parameters from the neuronal avalanche analysis and the spectral exponent.
Conclusion: 
Recent studies pointed out agreements of critical dynamics with the current most influencing theories in the field of consciousness research, the global workspace theory and the integrated information theory. Thus, the framework of SOC as a neurodynamical parameter for consciousness seems promising. However, identified experimental work was small in numbers, and a heterogeneity of applied analytical tools as a surrogate measure of criticality was observable, which limits the generalizability of findings.