cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Galaxy Evolution in the z=0.4274 Cluster MS1621.5+2640
Creators: name: Morris, S. L.
name: Hutchings, J. B.
name: Carlberg, R. G.
name: Yee, H. K. C.
name: Ellingson, E.
name: Balogh, M. L.
name: Abraham, R. G.
name: Smecker-Hane, T. A.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We discuss the galaxy population of the rich cluster MS1621.5+2640 at z=0.4274, based on spectra and imaging in a field of size 9 arcmin by 23 arcmin (~2 by 5 h**-1 Mpc). The sample comprises 277 galaxies, of which 112 are cluster members, 7 are `near-members', and 47 are field galaxies in the redshift range 0.37<=z<=0.50. The results are analyzed and compared with the z=0.2279 rich cluster Abell 2390. MS1621.5+2640 has a higher blue fraction, a younger stellar population, and is a less evolved cluster. We do not find strong evidence of significant excess star formation compared with the field, although there is a small population of outlying near-members that is unusually blue and that may be affected by the cluster. There is a substantial population of red galaxies with significant Hdelta absorption, which are not easily explained by any simple form of modeled star formation history. We detect two distinct populations of cluster galaxies: those where star formation ceased some time ago, and those with a gradual decrease over many Gyr. Our data suggests that the cluster formed by accretion from the field, with truncation of the star formation beginning at very large radii (>2 times the virial radius). The truncation process does not seem to be a sharp one though, in that lower-luminosity early-type galaxies in the inner core of the cluster are seen with significant Hdelta absorption, indicating some star formation within the last 1-2 Gyr. Some combination of stripping of gas from the outer parts of the galaxy, together with gradual exhaustion of the gas in the inner parts would be consistent with our data.
description: 46 pages, 20 figures. Accepted for publication in ApJ. Full text and figures available at http://www.hia.nrc.ca/STAFF/slm/ms1621/
MPEC 2024-G113 : DAILY ORBIT UPDATE (2024 April 9)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Sum Rules for B(M1,0+ -> 1+) Strength in IBM-3 and IBM-4
Creators: name: Halse, P.
name: Van Isacker, P.
name: Barrett, B. R.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Sum rules for $B(M1,0^+_1\rightarrow1^+_i)$ strength are derived for even-even nuclei in the isospin-invariant forms of the IBM, IBM-3 and IBM-4, in the cases where the respective natural internal symmetries, isospin $U$(3) and $U(6)\supset SU$(4), are conserved. Subsequently, the total strength is resolved into its component partial sums to the allowed isospins (and $SU(4)$ representations in IBM-4). In cases where the usual IBM dynamical symmetries are also valid, a complete description of all $B(M1,0^+_1\rightarrow1^+_i)$ is given. In contrast to IBM-2, there is fragmentation of the strength even in the dynamical symmetry cases, for $T\neq 0$, over two states in IBM-3, and over three states in IBM-4. The presence of $pn$ bosons in the ground state of the extended versions reduces the expected strength from that for IBM-2, allowing in principle the possibility of using $B(M1)$ data for a given nucleus to infer which version is the most appropriate.
description: 8 pages in LATEX with no figures
Prediction of birth weight small for gestational age with and without preeclampsia by angiogenic markers: an Odense Child Cohort study
Creators: name: Thorsen, Lena Heidi Bækgaard
name: Andersen, Louise Bjørkholt
name: Birukov, Anna
name: Lykkedegn, Sine
name: Dechend, Ralf
name: Jørgensen, Jan Stener
name: Christesen, Henrik Thybo
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: Purpose: To investigate the predictive performance of placental growth factor (PlGF) and soluble FMS-like kinase 1 (sFlt-1) on birth weight and small for gestational age (SGA), in a large, population-based cohort. Methods: Women enrolled in the population-based, prospective Odense Child Cohort Study with early (GA n = 1937) were included. The association between log-transformed values of the biomarkers and birth weight Z-score was studied using multivariate regression models. The prediction of SGA overall, and in women developing preeclampsia, by biomarkers was evaluated using receiver operating characteristic analyses. Results: No substantial associations between early pregnancy biomarkers and SGA were seen. PlGF measured in late pregnancy demonstrated the strongest association with birth weight Z-score (adjusted β-coefficient = 0.43 [95%CI = 0.35; 0.50]). The area under curve (AUC) for predicting SGA was higher for sFlt-1/PlGF compared to sFlt-1 (0.74 versus 0.63, p = .006) and reached excellent prediction for SGA after preeclampsia (AUC 0.94). Optimal sFlt-1/PlGF ratio cut-offs had higher negative predictive value (NPV) and positive predictive value (PPV) for SGA (cut-off > 5.0; NPV = 99.1%, PPV = 5.4%) compared to each marker individually. Conclusion: The sFlt-1/PlGF ratio is a potential predictor of SGA in population-based screening, particularly when preeclampsia is also present.
Reminiscences of Howard Ross Tolley, 1954
Publisher: name: Columbia University
Year: 2021
Subjects: Government executives--United States
Agricultural economists
New Deal, 1933-1939
Agricultural laws and legislation

description: Early life and teaching in Indiana; Office of Farm Management; development of bureaus in Department of Agriculture; Bureau of Agricultural Economics, 1915-29, 1938-43; Division of Agricultural Engineering; tariff policy; farm organizations; Secretaries Henry A. Wallace and William Jardine; outlook work; Giannini Foundation, University of California, 1930-33, 1935-36; Agricultural Adjustment Administration, 1933-35, 1936-38; Office of Price Administration; interim commission of the Food and Agriculture Organization
Reminiscences of Hu Shih : oral history, 1958
Publisher: name: Columbia University
Year: 2020
Subjects: Diplomats--China
College presidents--China
Chinese literature
Zen Buddhism

description: Family and early life; student days in the United States, 1910-17; working for a Chinese renaissance: theories of literary reform, analyses of early Chinese philosophy, discoveries in the history of Zen Buddhism, critical studies of major Chinese novels
The RNA-binding protein LARP1 as potential biomarker and therapeutic target in ovarian cancer
Creators: name: Hopkins, Tom
Publisher: name: Imperial College London
Year: 2014

description: Ovarian cancer is the most lethal gynaecological malignancy, responsible for over 4,000 deaths each year in the UK. There is growing evidence that mRNA-binding proteins (RBPs) can be post-transcriptional drivers of cancer progression. Here, I investigated the expression of the RBP LARP1 in ovarian malignancies and role of the protein in ovarian cancer cell biology. LARP1 is highly expressed at both an mRNA and protein level in ovarian cancers compared with benign tumours and normal ovarian tissue. I show that higher levels of LARP1 in tumour tissue are predictive of poor patient survival. Consistent with this clinical finding, in xenograft studies knockdown of LARP1 expression causes a dramatic reduction in tumour growth. In vitro, LARP1 knockdown is associated with increased apoptosis, and is sufficient to restore platinum sensitivity in chemotherapy-resistant cell lines. Furthermore, LARP1 is required to maintain cancer stem cell marker-positive populations, and knockdown decreases tumour-initiating potential, as demonstrated by in vivo limiting dilution assays. Transcriptome deep-sequencing following LARP1 knockdown revealed altered expression of multiple genes linked to survival and evasion of apoptosis, including BCL2 and BIK. Transcripts of both genes are in complex with LARP1 protein, and LARP1 maintains the stability of BCL2 mRNA, whilst actively destabilising BIK transcripts. This effect is mediated at the level of the 3’ untranslated region. I therefore conclude that by differentially regulating mRNA stability, LARP1 is a key post-transcriptional driver of tumourigenicity and cell survival in ovarian cancer.
title: ADCO, Cartulaire de Fontenay, second fragment (XIIIe siècle), Cart. 201 (15 H 9), folios 47-142, f. 001v
Creators: name: de la Côte d'Or, Archives départementales
name: Projet CBMA
name: CG21/F.PETOT/2009
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Fontenay, second fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), folios 47-142. Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Fontenay, second fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), folios 47-142, f. 001v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Fontenay
description: Provenance: http://www.wikidata.org/entity/Q464918
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb119679755
description: Provenance: https://www.geonames.org/7874015
description: Provenance: http://www.idref.fr/027691802/id
Learning compact q-space representations for multi-shell diffusion-weighted MRI
Creators: name: Christiaens, Daan
name: Cordero-Grande, Lucilio
name: Hutter, Jana
name: Price, Anthony N.
name: Deprez, Maria
name: Hajnal, Joseph V.
name: Tournier, J-Donald
Publisher: name: arXiv
Year: 2018
Subjects: subject: Medical Physics (physics.med-ph)
subject: FOS: Physical sciences

description: Diffusion-weighted MRI measures the direction and scale of the local diffusion process in every voxel through its spectrum in q-space, typically acquired in one or more shells. Recent developments in microstructure imaging and multi-tissue decomposition have sparked renewed attention in the radial b-value dependence of the signal. Applications in motion correction and outlier rejection therefore require a compact linear signal representation that extends over the radial as well as angular domain. Here, we introduce SHARD, a data-driven representation of the q-space signal based on spherical harmonics and a radial decomposition into orthonormal components. This representation provides a complete, orthogonal signal basis, tailored to the spherical geometry of q-space and calibrated to the data at hand. We demonstrate that the rank-reduced decomposition outperforms model-based alternatives in human brain data, whilst faithfully capturing the micro- and meso-structural information in the signal. Furthermore, we validate the potential of joint radial-spherical as compared to single-shell representations. As such, SHARD is optimally suited for applications that require low-rank signal predictions, such as motion correction and outlier rejection. Finally, we illustrate its application for the latter using outlier robust regression.
description: Accepted author manuscript, including supplementary materials
X-ray spectroscopy of the broad line radio galaxy 3C111
Creators: name: Reynolds, C. S.
name: Iwasawa, K.
name: Crawford, C. S.
name: Fabian, A. C.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present an ASCA observation of the broad line radio galaxy 3C111. The X-ray spectrum is well described by a model consisting of a photoelectrically-absorbed power-law form. The inferred absorbing column density is significantly greater than expected on the basis of 21-cm measurements of Galactic HI. Whilst this may be due intrinsic absorption from a circumnuclear torus or highly warped accretion disk, inhomogeneities and molecular gas within the foreground giant molecular cloud may also be responsible for some of this excess absorption. We also claim a marginal detection of a broad iron Ka line which is well explained as being a fluorescent line originating from the central regions of a radiatively-efficient accretion disk. This line appears weak in comparison to those found in (radio-quiet) Seyfert nuclei. We briefly discuss the implications of this fact.
description: 7 pages including 2 postscript figures. Accepted for publication in MNRAS
The evaluation of positron emission tomography to assess pharmacodynamics and pahrmacokinetics of anti cancer drugs
Creators: name: Gupta, Nishi
Publisher: name: Imperial College London
Year: 2008

description: Positron emission tomography (PET) is a non-invasive imaging technique that is emerging as a useful tool in the field of cancer medicine particularly in drug development. The purpose of this thesis has been to perform clinical studies using two different radiotracers, 5-[^V]fIuorouracil (5-['^F]FU) and 2-[''C]thymidine, to assess pharmacokinetic and pharmacodynamic parameters respectively, which were derived from PET imaging and to establish the contribution that PET can add to drug development, in vivo, in man. Aims: 1) Quantify the pharmacodynamic effects of cytotoxic agents in tumour and normal tissue using 2-["C]thymidine 2) Measure changes in tumour and normal tissue pharmacokinetics of 5-Fluorouracil in response to the modulating agents carbogen and nicotinamide or interferon 3) Assessment of blood flow change in tumour and normal tissue to carbogen and nicotinamide or interferon 4) Interpretation of PET data using novel analysis methods with modified Patlak and spectral analysis Methods: In the 5-['^]FU study, patients with metastatic gastrointestinal cancer underwent PET scanning at the start of 2 separate chemotherapy cycles. The 2nd scan was performed after the administration of carbogen and nicotinamide or interferon. In the 2-["C]thymidine study patients receiving chemotherapy were scanned before commencing chemotherapy, and 1 week after the 3''' cycle of chemotherapy. Patients also had conventional imaging before the start of and after 3 cycles of treatment. Findings: After carbogen and nicotinamide administration, 5-['^]FU uptake was increased in tumour, but not in normal tissue. Regional perfusion was elevated in tumours but decreased in kidneys after carbogen and nicotinamide. After interferon administration, there was an increase in 5-['^]FU retention in tumours, but no increase in uptake. Regional perfusion in tumour and normal tissue was unaltered by interferon. Retention of 2-["C]thymidine decreased in tumour in keeping with the results of conventional radiology, suggesting a pathological response, assessed in vivo, to chemotherapy.
sd-Shell Study with a Multi-Configuration Mixing Approach designed for Large Scale Nuclear Structure Calculations
Creators: name: Bender, E.
name: Schmid, K. W.
name: Faessler, Amand
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A systematic numerical investigation of a recently developed nuclear structure approach is presented which diagonalizes the Hamiltonian in the space of the symmetry-projected Hartree-Fock-Bogoliubov (HFB) vacuum and symmetry-projected quasiparticle excitations with respect to it. The underlying HFB transformation, which is assumed to be time-reversal and axially symmetric, is determined by variation after the projection. The model allows the use of large basis systems. It has been applied to the calculation of energy spectra of several even-even, odd-odd and odd mass nuclei in the sd shell with mass numbers reaching from A=20 to 30. The Chung-Wildenthal interaction has been used. Good agreement with the exact shell model diagonalization and a considerable improvement on a previous approach, where the HFB transformation was significantly more restricted, is obtained.
description: 21 pages LaTeX file, 2 LaTeX tables, 7 Postscript figures
Synthesis of optically-labelled vanadyl complexes and their evaluation as protein tyrosine phosphatase inhibitors and intracellular probes
Creators: name: Collins, Juliet Claire
Publisher: name: Imperial College London
Year: 2016

description: Cysteine based phosphatases (CBPs) are a diverse family of enzymes that act to remove the phosphate group from proteins, phosphatidylinositols and other biomolecules, thereby counteracting the effects of kinases. Due to the wide range of roles they play in the cell, the CBPs are implicated in many diseases such as cancer, diabetes and neurodegenerative disorders, and therefore it is of interest to develop compounds to study these enzymes. Within our group, vanadium compounds have been shown to inhibit the CBPs with a potency and selectivity that can be tuned by varying the ligand and the oxidation state of the vanadium centre. One subset of interest is the vanadium complexes of 3-hydroxypicolinic acid which have an inhibition range against phosphatases of low nanomolar to high micromolar depending on the oxidation state of vanadium and the enzyme studied. A small selection of novel fluorescent vanadyl complexes based on the hydroxypicolinic acid motif have been synthesised as novel phosphatase inhibitors. Incorporation of an amine-functionalised spacer between the picolinate ligands provided a handle for incorporation of a fluorescent group away from the picolinate-vanadyl core. These compounds were then tested against a range of phosphatases to determine their potency and selectivity as inhibitors of CBPs. The complexes showed good inhibition properties against the CBPs investigated in a range similar to that of free vanadyl. The fluorophore was used to study the interaction of the vanadyl complexes with the enzymes, and to investigate cell uptake. Fluorescence quenching and anisotropy assays were carried out to look at the stability of complexes in assay conditions. From the data obtained it appears that the vanadyl complexes are stable in the presence of the enzymes and under assay conditions. Preliminary data also indicate that the complexes are taken up into cells and therefore can be investigated as intracellular probes.
Improving memory access performance for irregular algorithms in heterogeneous CPU/FPGA systems
Creators: name: Bean, Andrew
Publisher: name: Imperial College London
Year: 2016

description: Many algorithms and applications in scientific computing exhibit irregular access patterns as consecutive accesses are dependent on the structure of the data being processed and as such cannot be known a priori. This manifests itself as a lack of temporal and spatial locality meaning these applications often perform poorly in traditional processor cache hierarchies. This thesis demonstrates that heterogeneous architectures containing Field Programmable Gate Arrays (FPGAs) alongside traditional processors can improve memory access throughput by 2-3x by using the FPGA to insert data directly into the processor cache, eliminating costly cache misses. When fetching data to be processed directly on the FPGA, scatter-gather Direct Memory Access (DMA) provides the best performance but its storage format is inefficient for these classes of applications. The presented optimised storage and generation of these descriptors on-demand leads to a 16x reduction in on-chip Block RAM usage and a 2/3 reduction in data transfer time. Traditional scatter-gather DMA requires a statically defined list of access instructions and is managed by a host processor. The system presented in this thesis expands the DMA operation to allow data-driven memory requests in response to processed data and brings all control on-chip allowing autonomous operation. This dramatically increases system flexibility and provides a further 11% performance improvement. Graph applications and algorithms for traversing and searching graph data are used throughout this thesis as a motivating example for the optimisations presented, though they should be equally applicable to a wide range of irregular applications within scientific computing.
Cordia sebestena Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Boraginales
Cordiaceae
Cordia
Cordia sebestena

description: Cordia sebestena, spec. nov.
2. Cordia foliis oblongo ovatis repandis scabris.
Sebestena scabra, flore miniato crispo. Dill. elth. 341. t.255. f.331.
Caryophyllus spurius inodorus, folio subrotundo scabro, flore racemoso hexapetaloide coccineo. Sloan. jam. 136. hist. 2. p.20. t.164. Raj. suppl. 86. Catesb. car. 2. p.91. t.91.
Habitat in America calidiore. ♄
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on pages 190-191, DOI: 10.5281/zenodo.3931989
Interventions for treating hyperemesis gravidarum: a network meta-analysis of randomized clinical trials
Creators: name: Kannan Sridharan
name: Sivaramakrishnan, Gowri
Publisher: name: Taylor & Francis
Year: 2018
Subjects: Medicine
Cell Biology
Pharmacology
Biotechnology
Cancer
Science Policy

description: Background: Several interventions were explored in clinical trials for treating hyperemesis gravidarum (HG). The present study is a network meta-analysis of such interventions. Methods: Electronic databases were searched for appropriate randomized clinical trials comparing interventions for treatment of patients with HG. Control of HG symptoms was the primary outcome and emetic episodes, hospital stay, nausea scores, patients requiring rescue antiemetics, hospital readmission, adverse events, and adverse pregnancy outcomes were the secondary outcome measures. Random-effects model was used and odds ratio (OR) [95% confidence interval (CI)] was the effect estimate for categorical outcomes and weighted mean difference (WMD) [95% confidence interval] for numerical outcomes. Results: Twenty studies were included in the systematic review and 18 in the meta-analysis. Acupuncture (OR: 18.9; 95% CI: 2.1, 168), acupressure (OR: 26.7; 95% CI: 2.5, 283.1) and methylprednisolone (OR: 6.7; 95% CI: 1.1, 38.8) were associated with better control of HG symptoms than standard of care. Acupressure decreases the requirement of rescue antiemetics (OR: 0.06; 95% CI: 0.01, 0.44); ondansetron with reduced hospital stay (WMD: −0.2; 95% CI: −0.31, −0.01) and diazepam with reduced risk of hospital admission (OR: 0.11; 95% CI: 0.01, 0.95). The quality of evidence is very low. Conclusion: Acupuncture, acupressure, and methylprednisolone were observed with better therapeutic benefits than other interventions for treating HG. However, the pooled estimates may change with the advent of results from future head-to-head clinical trials.
Performance Metrics for the Objective Assessment of Capacitive Deionization Systems
Creators: name: Hawks, Steven A.
name: Ramachandran, Ashwin
name: Porada, Slawomir
name: Campbell, Patrick G.
name: Suss, Matthew E.
name: Biesheuvel, P. M.
name: Santiago, Juan G.
name: Stadermann, Michael
Publisher: name: arXiv
Year: 2018
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: In the growing field of capacitive deionization (CDI), a number of performance metrics have emerged to describe the desalination process. Unfortunately, the separation conditions under which these metrics are measured are often not specified, resulting in optimal performance at minimal removal. Here we outline a system of performance metrics and reporting conditions that resolves this issue. Our proposed system is based on volumetric energy consumption (Wh/m$^3$) and throughput productivity (L/h/m$^2$) reported for a specific average concentration reduction, water recovery, and feed salinity. To facilitate and rationalize comparisons between devices, materials, and operation modes, we propose a nominal standard testing condition of removing 5 mM from a 20 mM NaCl feed solution at 50% water recovery for CDI research. Using this separation, we compare the desalination performance of a flow-through electrode (fte-CDI) cell and a flow between membrane (fb-MCDI) device, showing how significantly different systems can be compared in terms of generally desirable desalination characteristics. In general, we find that performance analysis must be considered carefully so to not allow for ambiguous separation conditions or the maximization of one metric at the expense of another. Additionally, for context we discuss a number of important underlying performance indicators and cell characteristics that are not performance measures in and of themselves but can be examined to better understand differences in performance.
The Galaxy Luminosity Function at z < 0.05: Dependence on Morphology
Creators: name: Marzke, R. O.
name: da Costa, L. N.
name: Pellegrini, P. S.
name: Willmer, C. N. A.
name: Geller, M. J.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We investigate the dependence of the local galaxy luminosity function on morphology using 5,404 galaxies from the recently enlarged Second Southern Sky Redshift Survey (SSRS2). Over the range -22 \le M_B \le -14 ($H_0 = 100 km/s/Mpc), the luminosity function of early-type galaxies is well fitted by a Schechter function with parameters M_*=-19.37^{+0.10}_{-0.11}, alpha=-1.00^{+0.09}_{-0.09} and phi_*=0.0044 +/- 0.0008 Mpc^{-3}. The spiral luminosity function is very similar and is well fitted by the parameters M_*=-19.43^{+0.08}_{-0.08}, alpha=-1.11^{+0.07}_{-0.06} and phi_*=0.0080 +/- 0.0014 Mpc^{-3} over the same range in absolute magnitude. The flat faint end of the early-type luminosity function is consistent with earlier measurements from the CfA Redshift Survey (Marzke et al. 1994) but is significantly steeper than the slope measured in the Stromlo-APM survey (Loveday et al. 1992). Combined with the increased normalization of the overall LF measured from intermediate redshift surveys, the flat faint-end slope of the E/S0 LF produces no-evolution models which reproduce the deep HST counts of early-type galaxies remarkably well. However, the observed normalization of the SSRS2 LF is consistent with the low value measured in other local redshift surveys. The cause of this low-redshift anomaly remains unknown. The luminosity function of irregular and peculiar galaxies in the SSRS2 is very steep: M_*=-19.78^{+0.40}_{-0.50}, alpha=-1.81^{+0.24}_{-0.24} and phi_*=0.0002 +/- 0.00008 Mpc^{-3}. The steep slope is consistent with the LFs measured for Sm-Im galaxies in the CfA survey, UV-selected galaxies (Treyer et al. 1997), star-forming field galaxies (Bromley et al. 1997) and the bluest galaxies in the SSRS2 (Marzke & da Costa 1997).
description: 35 pages + 9 figures + 4 tables. Latex 2.09 with AASTex v. 4.0, to appear in the Astrophysical Journal
Soft Bootstrap and Supersymmetry
Creators: name: Elvang, Henriette
name: Hadjiantonis, Marios
name: Jones, Callum R. T.
name: Paranjape, Shruti
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The soft bootstrap is an on-shell method to constrain the landscape of effective field theories (EFTs) of massless particles via the consistency of the low-energy S-matrix. Given assumptions on the on-shell data (particle spectra, linear symmetries, and low-energy theorems), the soft bootstrap is an efficient algorithm for determining the possible consistency of an EFT with those properties. The implementation of the soft bootstrap uses the recently discovered method of soft subtracted recursion. We derive a precise criterion for the validity of these recursion relations and show that they fail exactly when the assumed symmetries can be trivially realized by independent operators in the effective action. We use this to show that the possible pure (real and complex) scalar, fermion, and vector exceptional EFTs are highly constrained. Next, we prove how the soft behavior of states in a supermultiplet must be related and illustrate the results in extended supergravity. We demonstrate the power of the soft bootstrap in two applications. First, for the N= 1 and N=2 CP^1 nonlinear sigma models, we show that on-shell constructibility establishes the emergence of accidental IR symmetries. This includes a new on-shell perspective on the interplay between N=2 supersymmetry, low-energy theorems, and electromagnetic duality. We also show that N=2 supersymmetry requires 3-point interactions with the photon that make the soft behavior of the scalar O(1) instead of vanishing, despite the underlying symmetric coset. Second, we study Galileon theories, including aspects of supersymmetrization, the possibility of a vector-scalar Galileon EFT, and the existence of higher-derivative corrections preserving the enhanced special Galileon symmetry. This is addressed by soft bootstrap and by application of double-copy/KLT relations applied to higher-derivative corrections of chiral perturbation theory.
description: 71 pages, no figures. v2: significant new material about the N=2 CP^1 NLSM; typos corrected
Reminiscences of Hugh A. Parker: 1972
Publisher: name: Columbia University
Year: 2020
Subjects: Veterans
Air pilots
Aeronautics, Military
Aviation

description: Army Air Corps cadet training, 1928-1931; flight instructor, 1931-1934; duty in the Philippines and Argentina, 1934-1941; teaching Dwight D. Eisenhower to fly; impressions of General MacArthur and General Perón
Near Infrared Observations of a Redshift 4.92 Galaxy: Evidence for Significant Dust Absorption
Creators: name: Soifer, B. T.
name: Neugebauer, G.
name: Franx, M.
name: Matthews, K.
name: Illingworth, G.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Near-infrared imaging and spectroscopy have been obtained of the gravitationally lensed galaxy at z=4.92 discovered in HST images by Franx et al. (1997). Images at 1.2, 1.6 and 2.2 microns show the same arc morphology as the HST images. The spectrum with resolution λ/ Δλ~ 70 shows no emission lines with equivalent width stronger than 100 A in the rest frame wavelength range 0.34 to 0.40 microns. In particular, [OII]3727 A and [NeIII]3869 A are not seen. The energy distribution is quite blue, as expected for a young stellar population with the observed Ly alpha flux. The spectral energy distribution can be fit satisfactorily for such a young stellar population when absorption by dust is included. The models imply a reddening 0.1 mag < E(B-V) < 0.4 mag. The stellar mass of the lensed galaxy lies in the range of 2 to 16 x 10^9 Msun. This is significantly higher than estimates based on the HST data alone. Our data imply that absorption by dust is important to redshifts of ~5.
description: LaTeX with ApJ journal format, 2 postscript figures, ApJL, accepted
Unravelling the progression of unfolded protein Rresponse in a model system of familial Alzheimer’s disease
Creators: name: Stefani Chrysoula, Ioanna
Publisher: name: Imperial College London
Year: 2014

description: Alzheimer’s disease (AD) is the most common form of dementia disorders and, yet, there is no preventative or curative treatment. It is associated with the progressive loss of memory and cognition and clinically divided into sporadic and familial forms. Familial Alzheimer’s disease (FAD) has predominantly a genetic predisposition with inherited mutations in the amyloid-β precursor protein (APP) and presinilin genes, which promote APP processing through the amyloidogenic pathway. This results in the release of the Aβ peptide, a major neurotoxic agent in AD progression. Accumulation of unfolded and misfolded disease-specific proteins (including Aβ and tau proteins) in neuronal cells perturbs endoplasmic reticulum (ER) homeostasis, leading to the onset of a cellular stress cascade called unfolded protein response (UPR), markers of which are upregulated in AD brain specimens. This suggests a possible role for ER stress in activation and the pathogenesis of AD. The research aimed to investigate the dynamic response of the UPR in an experimental model system of the disease combined with a computational model. For this purpose human neuroblastoma cell lines overexpressing the wild-type (APPWT) and two mutant forms of APP (APPMUT) associated with FAD were generated. Gene expression analysis of UPR markers revealed that overexpression of APP induces preconditioning of ER stress in all cell lines but with a stronger response in FAD-associated mutants. The progression sequence of UPR in APPWT and APPMUT was investigated in a time-course manner following the application of chemical stress. The results revealed that APPMUT exhibited the highest global response to chemically induced stress with a similar pattern. A computational model of the mammalian UPR was then generated and used to understand the dynamics of UPR. The model was able to reproduce our experimental data, which included pre-existing genetic factors (mutations in APP-associated with FAD) and a mimic of environmental triggers (induction of stress) consequently triggering the stress response. It suggested a different protein load and magnitude of transcriptional activation upon stress among the three cell lines. This was followed by in silico case studies exploring the effect of drugs targeting different branches of the UPR. This study proposes a novel multidisciplinary platform that could be further used for the development of therapeutics for AD. As the familial and sporadic form of the disease have similar neuropathological characteristics, drugs efficacious for FAD will also be beneficial for the most common form of AD.
A Multiple Merger Model for the Origin of Ultraluminous Infrared Galaxies
Creators: name: Taniguchi, Yoshiaki
name: Shioya, Yasuhiro
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: It has been often considered that the dissipative collapse caused by a merger of two gas-rich galaxies is responsible for the intense nuclear starbursts or the nonthermal quasar activity in ultraluminous infrared galaxies due to the efficient fueling induced by it. It is also widely known that Ultraluminous Infrared Galaxies (ULIGs) are often found in merging systems. Some ULIGs, such as Arp 220, show two compact starburst regions which are considered to be associated with two galactic nuclei in the process of merging. However, since a merger between two galaxies may make only one compact starburst region, we suggest the possibility that double-nucleus ULIGs are composed of two merging nuclei, each of which contains a couple of galactic nuclei.
description: 13 pages with two figures. To appear in THE ASTROPHYSICAL JOURNAL (Letters)
Fusion reactions in molecules via nuclear threshold resonances
Creators: name: Belyaev, V. B.
name: Motovilov, A. K.
name: Sandhas, W.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: It is widely accepted that in molecular systems the nuclear interaction plays a negligible role, because of the strong Coulomb repulsion of the nuclei at small distances. We are going to show that this is not always true. The existence of an extended nuclear resonance may lead to considerably enhanced nuclear reaction rates in appropriately prepared molecules. Especially we point out that p+p+ ^{16}O, i.e., the constituents of water, can form a ^{18}Ne(1^-) threshold resonance which decays under energy release into ^{17}F and a proton.
description: RevTeX, 9.4 Kb; Published version of the paper
Additional file 1: of Oldest ctenodactyloid tarsals from the Eocene of China and evolution of locomotor adaptations in early rodents
Creators: name: Fostowicz-Frelik, Łucja
name: Li, Qian
name: Ni, Xijun
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: Plant Biology

description: Table S1. Specimens examined in morphological analyses. Table S2. Guide to the bone measurements – calcaneus. Table S3. Guide to the bone measurements – astragalus. Figure S1. Measurements of the tarsal elements shown at the right calcaneus (A, B) and right astragalus (C, D) of Tamquammys robustus (IVPP coll. V24136.1 and IVPP coll. V24136.4, respectively) from the Arshanto Formation (early Eocene) of Nuhetingboerhe section, Erlian Basin, Nei Mongol, China. Figure S2. Ratios for calcaneal measurements. A, slenderness ratio (CW/CL); B, calcaneal load arm (CBL/CL); C tuber proportions (TCW/TCdp); D, relative length of the ectal facet (CEL/CL); E, proportions of the calcaneocuboid facet (CaCuW/CaCuL). Abbreviations: A.te, Arvicola terrestris; C.cr, Cricetus cricetus; C.lud, Cynomys ludovicianus; G.gl, Glis glis; G.el, Gomphos elkema; M.ma, Marmota marmota; M.mu, Mus musculus; O.pa, Ochotona pallasi; O.zi, Ondatra zibethicus; Par., paramyine rodent; Pur, Purgatorius; R.no, Rattus norvegicus; S.vu, Sciurus vulgaris; T.gl, Tupaia glis; T.mi, Tribosphenomys minutus; T.ro, Tamquammys robustus; T.wi, Tamquammys wilsoni. Colors: red for rodents; yellow for Rodentiaformes; green for stem duplicidentate and lagomorph; blue for Euarchonta (basal primate and Scandentia). Figure S3. Ratios for astragalar measurements. A, trochlear ratio (TW/AL); B, neck ratio (NL/AL); C head proportions (HW/NL); D, trochlear crests ratio (MCL/LCL); abbreviations as in Figure S2. Table S4. Measurements of calcaneus of Tamquammys robustus, T. wilsoni, and comparative taxa (in mm). Table S5. Measurements of astragalus of Tamquammys robustus and T. wilsoni and comparative taxa (in mm). Table S6. Results of Kaiser-Meyer-Olkin (KMO) Test for sampling adequacy. Table S7. Eigenvalues for calcaneus (A) and astragalus (B) PCA analysis. Figure S4. PCA loadings for the calcaneus. Loadings are for variables described in Table S2 (Ca1–15). Figure S5. PCA loadings for the astragalus. Loadings are for variables described in Table S3 (As1–12). (DOCX 1745 kb)
EUMELI
Creators: name: BUAT-MENARD Patrick
Publisher: name: Sismer
Year: 1989

description: Le programme EUMELI (une des composantes de FPO) a pour but d'etudier a l'echelle du bassin tropical de l'Atlantique nord-est trois zonesgeographiques :- la zone de haute productivite liee a l'upwelling mauritanien (zone eutrophe)- une zone oceanique : le plateau abyssal du Cap Vert en regime oligotrophe- une zone intermediaire : la Terrasse du Cap Vert en regime mesotrophe.
Polychromatic fluence: calculation and application in ultraviolet reactors for water treatment
Creators: name: Mayor-Smith, Ian
Publisher: name: Imperial College London
Year: 2014

description: IIn recent decades the application of UV disinfection technology in water treatment has rapidly increased on a global scale, however important uncertainties remain regarding; the methods to achieve consistent and accurate measurement of polychromatic UV output, the fluence-response of microorganisms to UV wavelengths over the entire polychromatic lamp output range, and the optimal lamp conditions and compositions to optimise polychromatic UV disinfection performance. This research aimed to address each of these areas of uncertainty. First, limitations in the existing methods that are used for lamp output measurement were identified and quantified in terms of their potential to cause significant errors in polychromatic UV fluence calculation; solutions are proposed to overcome these limitations in future polychromatic fluence measurements. Next, a novel experimental apparatus was constructed, achieving the necessary spectral requirements to produce a high resolution action spectra for waterborne microorganisms over the 200-300 nm wavelength range. Application of this experimental setup to the comparison of the fluence-response of T1 and T1UV phage, common organisms used in UV reactor validation, identified important differences in UV sensitivity dependent on host selection, and high resolution action spectra were then produced for T1UV with two hosts over the full polychromatic UV range for the first time. Also, new viral surrogates were identified using a theoretical genomic model to predict their UV sensitivities, two of which were identified as having the potential to extend the upper UV fluence validation test limits. Finally, the production of a novel high pressure plasma discharge polychromatic lamp was achieved without the use of mercury, showing considerable potential for future applications.
Cordia glabra Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Boraginales
Cordiaceae
Cordia
Cordia glabra

description: Cordia glabra, spec. nov.
3. Cordia foliis ovatis integerrimis.
Cordia nucis iuglandis folio. Plum. gen.13?
Habitat in America meridionali. ♄
Folia exacte ovata, laevia, in neutra pagina scabra. Corollae tubus longitudine tantum calycis.
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 191, DOI: 10.5281/zenodo.3931989
Elliptic free-fermion model with OS boundary and elliptic Pfaffians
Creators: name: Motegi, Kohei
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We introduce and study a class of partition functions of an elliptic free-fermionic face model. We study the partition functions with a triangular boundary using the off-diagonal $K$-matrix at the boundary (OS boundary), which was introduced by Kuperberg as a class of variants of the domain wall boundary partition functions. We find explicit forms of the partition functions with OS boundary using elliptic Pfaffians. We find two expressions based on two versions of Korepin's method, and we obtain an identity between two elliptic Pfaffians as a corollary.
description: 23 pages, 8 figures
The regulation of FOXM1 in breast cancer
Creators: name: Kongsema, Mesayamas
Publisher: name: Imperial College London
Year: 2014

description: Breast cancer is the most commonly diagnosed cancer in women worldwide. In the UK, there is 1 in 8 of women that have a risk of being diagnosed with breast cancer in a lifetime. Clinically, the common treatment using for breast cancer therapy are combinations of surgery, radiotherapy, endocrinal (hormonal) therapy and chemotherapy. The DNA damaging agent epirubicin has been shown to be an effective chemotherapeutic drug for breast cancer treatment. Nevertheless, there are more than 90% of patients with metastatic cancer that found to be resistant to the drug. FOXM1 is a transcription factor that has been reported to be responsible for a resistance to various chemotherapeutics, including epirubicin. Accumulating evidence has revealed that FOXM1 is regulated by modifications at the post-translational levels. In this study, I show that FOXM1 can also be regulated by SUMOylation and ubiquitination. In response to epirubicin treatment, FOXM1 is modified primarily by SUMO1, and not SUMO2/3, in breast cancer cells. The SUMOylation of FOXM1 is targeted by RNF168 and leads to its ubiquitination, nuclear exportation and degradation through the proteasome degradation pathway. Unfortunately, the study about OTUB1 about its property in deubiquitinating ubiquitinated FOXM1 does not show the significant results. Collectively, this thesis identifies and characterises the role of SUMOylation, ubiquitination and RNF168 in modulating FOXM1 expression and activity, by promoting its degradation. My data suggest that these proteins and PTMs might be interesting targets for the development of novel therapeutic strategies for breast cancer treatment and for overcoming conventional chemotherapeutic drug resistance.
Direct radiative capture of p-wave neutrons
Creators: name: Mengoni, A.
name: Otsuka, T.
name: Ishihara, M.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The neutron direct radiative capture (DRC) process is investigated, highlighting the role of incident p-wave neutrons. A set of calculations is shown for the 12-C(n,gamma) process at incoming neutron energies up to 500 keV, a crucial region for astrophysics. The cross section for neutron capture leading to loosely bound s, p and d orbits of 13-C is well reproduced by the DRC model demonstrating the feasibility of using this reaction channel to study the properties of nuclear wave functions on and outside the nuclear surface. A sensitivity analysis of the results on the neutron-nucleus interaction is performed for incident s- as well as p-waves. It turned out that the DRC cross section for p-wave neutrons is insensitive to this interaction, contrary to the case of incident s-wave neutrons. PACS number(s): 25.40Lw,21.10Gv,23.40.Hc
description: 16 pages, REVTeX file, PostScript file, .dvi file
Optical Gravitational Lensing Experiment. The Distance Scale: Galactic Bulge - LMC - SMC
Creators: name: Udalski, A.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We analyze the mean luminosity of three samples of field RRab Lyr stars observed in the course of the OGLE microlensing experiment: 73 stars from the Galactic bulge and 110 and 128 stars from selected fields in the LMC and SMC, respectively. The fields are the same as in the recent distance determination to the Magellanic Clouds with the red clump stars method by Udalski et al (1998). We determine the relative distance scale d_{GB}:d_{LMC}:d_{SMC} equal to: (0.194+/-0.010):1.00:(1.30+/-0.08). We calibrate our RR Lyr distance scale with the recent calibration of Gould and Popowski (1998) based on statistical parallaxes. We obtain the following distance moduli to the Galactic bulge, LMC and SMC: m-M=14.53+/-0.15, m-M=18.09+/-0.16 and m-M=18.66+/-0.16 mag. We use the RR Lyr mean V-band luminosity at the Galactic bulge metallicity as the reference brightness and analyze the mean, I-band luminosity of the red clump stars in objects with different ages and metallicities. We add to our analysis the metal poor Carina dwarf galaxy which contains old RR Lyr stars and intermediate age red clump population. We find a weak dependence of the mean red clump brightness on metallicity and we calibrate its zero point with the nearby local red clump stars measured by Hipparcos: M^{RC}_I=(0.09+/-0.03) *[Fe/H]^{RC}-0.23+/-0.03. Our revised red clump distance moduli to the Galactic bulge, LMC and SMC are m-M=14.53+/-0.06, m-M=18.13+/-0.07 and m-M=18.63+/-0.07 mag, respectively. The distance modulus to the Carina galaxy is m-M=19.84+/- 0.07 mag. Excellent agreement of RR Lyr and red clump distances which have independent absolute calibrations confirms the short distance scale to the LMC.
description: 25 pages, Latex, 7 Figures. Submitted to Acta Astronomica