cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Reviews Pages: The Times They are A-Changin’ 3(2019)
Creators: name: Angiello, Gennaro
name: Gaglione, Federica
name: Guida, Carmen
name: Morosini, Rosa
name: Tulisi, Andrea
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2019

description: Starting from the relationship between urban planning and mobility management, TeMA has gradually expanded the view of the covered topics, always remaining in the groove of rigorous scientific in-depth analysis. During the last two years a particular attention has been paid on the Smart Cities theme and on the different meanings that come with it. The last section of the journal is formed by the Review Pages. They have different aims: to inform on the problems, trends and evolutionary processes; to investigate on the paths by highlighting the advanced relationships among apparently distant disciplinary fields; to explore the interaction’s areas, experiences and potential applications; to underline interactions, disciplinary developments but also, if present, defeats and setbacks. Inside the journal the Review Pages have the task of stimulating as much as possible the circulation of ideas and the discovery of new points of view. For this reason, the section is founded on a series of basic’s references, required for the identification of new and more advanced interactions. These references are the research, the planning acts, the actions and the applications, analysed and investigated both for their ability to give a systematic response to questions concerning the urban and territorial planning, and for their attention to aspects such as the environmental sustainability and the innovation in the practices. For this purpose, the Review Pages are formed by five sections (Web Resources; Books; Laws; Urban Practices; News and Events), each of which examines a specific aspect of the broader information storage of interest for TeMA.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 12 No 3 (2019): The Times They Are a-Changin'
Additional file 6: of MTH1 deficiency selectively increases non-cytotoxic oxidative DNA damage in lung cancer cells: more bad news than good?
Creators: name: Abbas, Hussein
name: Kheloud Alhamoudi
name: Evans, Mark
name: Jones, George
name: Foster, Steven
Publisher: name: Figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Apoptotic dose responses of H23 and H522 cell lines to various genotoxic agents. Apoptosis assay to determine cell viability following 48 h treatment with different agents. In addition, cells were exposed to VP-16 for positive controls, and DMSO (0.5–2% v/v) and untreated negative control samples were also included. Harvested cells were dual stained with annexin V-FITC/PI and assessed by flow cytometry to detect both early and late apoptosis. a Hydrogen peroxide treatment of H23 and H522 cells. b Gemcitabine treatment of H23 and H522 cells. c Cisplatin treatment of H23 and H522 cells. Percentage values from independent experiments were used to calculate final mean values and SD. Error bars represent SD. All experiments were repeated more than 3 times. Asterisks indicate a significant difference relative to corresponding DMSO controls (****P
Neutron background signal in superheated droplet detectors of the Phase II SIMPLE dark matter search
Creators: name: Fernandes, A. C.
name: Kling, A.
name: Felizardo, M.
name: Girard, T. A.
name: Ramos, A. R.
name: Marques, J. G.
name: Prudêncio, M. I.
name: Marques, R.
name: Carvalho, F. P.
name: Lázaro, I.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The simulation of the neutron background for Phase II of the SIMPLE direct dark matter search experiment is fully reported with various improvements relative to previous estimates. The model employs the Monte Carlo MCNP neutron transport code, using as input a realistic geometry description, measured radioassays and material compositions, and tabulated (α,n) yields and spectra. Developments include the accounting of recoil energy distributions, consideration of additional reactions and materials and examination of the relevant (α,n) data. A thorough analysis of the simulation results is performed that addresses an increased number of non-statistical uncertainties. The referred omissions are seen to provide a net increase of 13$\%$ in the previously-reported background estimates whereas the non-statistical uncertainty rises to 25$\%$. The final estimated recoil event rate is 0.372 $\pm$ 0.002 (stat.) $\pm$ 0.097 (non-stat.) evt/kgd resulting in insignificant changes over the results of the experiment.
description: 35 pages, 8 figures, accepted for publication in Astroparticle Physics 2-Dec-2015
Katagami in Practice Exhibition Panels
Creators: name: Woodward, Sian
Publisher: name: Figshare
Year: 2018
Subjects: subject: Design
subject: History
subject: 130201 Creative Arts, Media and Communication Curriculum and Pedagogy
subject: FOS: Educational sciences

description: These are the interpretation panels for the 2018 Katagami in Practice Exhibition at Asia House. The Exhibition was put together by the Museum of Domestic Design & Architecture to showcase some of the outputs from the Arts Council England funded project 'Katagami in Pratice: Japanese Stencils in the Art School. The project started with 400 Japanese katagami stencils that form part of the Silver Studio collection, and were acquired by the Silver Studio in the late 19th century as inspiration for textile and wallpaper design. Several researcher and arts practitioners then developed project work inspired by these objects and the processes that went into making and using them. The panels outline the historical background and summarise the research outputs.
Air Transport Implications in Tourist Destinations. The Trapani Airport in Western Sicily
Creators: name: Calderon, Enrique
name: Ventura, Paolo
name: Massaro, Alessandro
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2019

description: This search following the Sicily, the largest island in the Mediterranean Sea (25,460 sq km) and a self-governing Region, located in the southernmost part of Italy, has at least four tourist-related airports, sited between the eastern and western coast, separated from each other by a vast territory without efficient transport links and suffering from many diverse environmental problems. Utilizing a desk search methodology based on GIS software, this paper discusses the impact upon the regional development of the tourist traffic of the Trapani Airport situated in the westernmost part of Sicily. Ultimately it analyzes the critical role of connectivity and accessibility in the development of the area and tourism, seeking a maximum involvement of stakeholders. The recent growth of low-cost carriers have had a definite impact on the economic growth of the entire territory, where those choices could determine the life or the death of firms and, inevitably, their annual incomes. Tourism and connectivity are strictly related, thus showing deficiencies of the area in terms of accessibility, as well as the trade-offs between the different government (central and local) investment policies and the specific benefits emerging from the airport in the regional mobility.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 12 No 3 (2019): The Times They Are a-Changin'
Land-Use and Transport integration polices and real estate values. The development of a GIS methodology and the application to Naples (Italy)
Creators: name: Carpentieri, Gerardo
name: Guida, Carmen
name: Chorus, Paul
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2019

description: The interactions between the Transport and the Land-Use Systems are complex and not widely analysed, causing uncertainties in decision-making processes. New governance tools are needed to support territorial transformations oriented to more sustainable use of soil resources, the transition towards more environmentally friendly transport modes and to greater accessibility equity to transport services. Moreover, these tools have to consider the interactions of external phenomena on the urban system, such as economic crisis and political issues. In this perspective, the research aims at developing a GIS-based methodology able to assess the impacts of interventions on the railway network and nodes on the urban environments, in terms of real estate values, as a proxy of urban requalification. The methodology consists of an ex-post spatial analysis procedure, applied to the city of Naples (Italy), where local and regional planning strategies, during the last decades, have been oriented towards an integrated approach between Transport and Land-Use Systems. The results show that in some catchment areas and concerning some types of properties, the effects of the world economic crisis on the real estate had less effect in terms of fall in prices. Moreover, the results show that the methodology is useful to quantitatively assess ex-post the main impacts of actions aimed at the integration between the Transport and Land-Use Systems, but its application could be extended to support the implementation of these strategies in different territorial context, on the basis of well-known best practices and their economic impacts on urban environment.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 12 No 3 (2019): The Times They Are a-Changin'
3D MHD simulation of polarized emission in SN 1006
Creators: name: Schneiter, E. M.
name: Velázquez, P. F.
name: Reynoso, E. M.
name: Esquivel, A.
name: De Colle, F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We use three dimensional magnetohydrodynamic (MHD) simulations to model the supernova remnant SN 1006. From our numerical results, we have carried out a polarization study, obtaining synthetic maps of the polarized intensity, the Stokes parameter $Q$, and the polar-referenced angle, which can be compared with observational results. Synthetic maps were computed considering two possible particle acceleration mechanisms: quasi-parallel and quasi-perpendicular. The comparison of synthetic maps of the Stokes parameter $Q$ maps with observations proves to be a valuable tool to discern unambiguously which mechanism is taking place in the remnant of SN 1006, giving strong support to the quasi-parallel model.
description: 6 pages, 4 figures, accepted by MNRAS
An Extensive Study of Residential Proxies in China
Creators: name: Yang, Mingshuo
name: Yu, Yunnan
name: Mi, Xianghang
name: Tang, Shujun
name: Guo, Shanqing
name: Li, Yilin
name: Zheng, Xiaofeng
name: Duan, Haixin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: We carry out the first in-depth characterization of residential proxies (RESIPs) in China, for which little is studied in previous works. Our study is made possible through a semantic-based classifier to automatically capture RESIP services. In addition to the classifier, new techniques have also been identified to capture RESIPs without interacting with and relaying traffic through RESIP services, which can significantly lower the cost and thus allow a continuous monitoring of RESIPs. Our RESIP service classifier has achieved a good performance with a recall of 99.7% and a precision of 97.6% in 10-fold cross validation. Applying the classifier has identified 399 RESIP services, a much larger set compared to 38 RESIP services collected in all previous works. Our effort of RESIP capturing lead to a collection of 9,077,278 RESIP IPs (51.36% are located in China), 96.70% of which are not covered in publicly available RESIP datasets. An extensive measurement on RESIPs and their services has uncovered a set of interesting findings as well as several security implications. Especially, 80.05% RESIP IPs located in China have sourced at least one malicious traffic flows during 2021, resulting in 52-million malicious traffic flows in total. And RESIPs have also been observed in corporation networks of 559 sensitive organizations including government agencies, education institutions and enterprises. Also, 3,232,698 China RESIP IPs have opened at least one TCP/UDP ports for accepting relaying requests, which incurs non-negligible security risks to the local network of RESIPs. Besides, 91% China RESIP IPs are of a lifetime less than 10 days while most China RESIP services show up a crest-trough pattern in terms of the daily active RESIPs across time.
description: To appear in ACM CCS 2022
Elders’ quality of life. A method to optimize pedestrian accessibility to urban services.
Creators: name: Gaglione, Federica
name: Gargiulo, Carmela
name: Zucaro, Floriana
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2019

description: The progressive ageing of population requires rethinking the spatial planning of the urban spaces and activities to guarantee the best accessibility and usability to urban services of interest for the elderly segment of the population. In this perspective, the paper provides a methodology oriented to reorganize the urban services to better satisfy the renewed needs of over 65, by classifying the areas of a city according to (i) the levels of urban accessibility and (ii) the Functional Accessibility Soft zones (FASzones). In fact, the FASzones are the parts of the city where elderly can easily reach their services of interest due to the presence of "optimal" pedestrian routes fitting their behaviours. The results provide local decision-makers with useful suggestions for deciding where and how to in on the distribution and location of services, in order to increase urban accessibility for the over 65 by improving their quality of life. This methodological aim represents a first step in the broader MOBILAGE research work aimed at defining strategies, tools and actions to improve the pedestrian accessibility to urban services and places for elderly users.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 12 No 3 (2019): The Times They Are a-Changin'
Understanding The Effects Of Stellar Multiplicity On The Derived Planet Radii From Transit Surveys: Implications for Kepler, K2, and TESS
Creators: name: Ciardi, David R.
name: Beichman, Charles A.
name: Horch, Elliott P.
name: Howell, Steve B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present a study on the effect of undetected stellar companions on the derived planetary radii for the Kepler Objects of Interest (KOIs). The current production of the KOI list assumes that the each KOI is a single star. Not accounting for stellar multiplicity statistically biases the planets towards smaller radii. The bias towards smaller radii depends on the properties of the companion stars and whether the planets orbit the primary or the companion stars. Defining a planetary radius correction factor $X_R$, we find that if the KOIs are assumed to be single, then, {\it on average}, the planetary radii may be underestimated by a factor of $\langle X_R \rangle \approx 1.5$. If typical radial velocity and high resolution imaging observations are performed and no companions are detected, this factor reduces to $\langle X_R \rangle \approx 1.2$. The correction factor $\langle X_R \rangle$ is dependent upon the primary star properties and ranges from $\langle X_R \rangle \approx 1.6$ for A and F stars to $\langle X_R \rangle \approx 1.2$ for K and M stars. For missions like K2 and TESS where the stars may be closer than the stars in the Kepler target sample, observational vetting (primary imaging) reduces the radius correction factor to $\langle X_R \rangle \approx 1.1$. Finally, we show that if the stellar multiplicity rates are not accounted for correctly, occurrence rate calculations for Earth-sized planets may overestimate the frequency of small planets by as much as $15-20$\%.
description: 10 pages, 6 Figures, Accepted for publication in The Astrophysical Journal (Fix typo in Equation 6 of original astroph submission; correction also submitted to Journal)
title: The impact of the use of adobe as masonry in the operational and embodied emissions of dwellings, considering the urban heat island effect and the changing climate in Puebla, Mexico.
Creators: name: Cruz Juarez, Roberto
Publisher: name: University of Liverpool Repository
Year: 2023

description: The aim of this research is to assess part of the environmental problems associated with the built environment in Puebla, which is the fourth largest metropolitan area in Mexico with over 3 million inhabitants and has one of the highest population growth rates in the country. This is done by using Environmental Product Declarations to analyse the embodied emissions in cement, which is the most widespread construction material in the area, and comparing it to adobe (unfired earth blocks). Two case study dwellings, each one built with one of these construction techniques, were analysed, quantifying their embodied emissions. Additionally, the performance of the dwellings was evaluated considering the impact of the urban heat island effect in the area. To do this, six locations across the urban sprawl of Puebla were selected, ranging from SITE 0, in the city centre, to SITE 5, 21.10km away. The case study dwellings were modelled in these two locations to determine their performance under the current climate. Then, projections were made for the year 2080 under three different representative concentration pathways for climate change, and the performance of the dwellings was assessed considering their indoor temperatures, and their electricity consumption if air conditioning was required. The city of Puebla was found to have an urban heat island effect that reflects on temperatures in the city’s centre being on average 2.43°C, and at times up to 11°C warmer than the areas surrounding the urban sprawl of town. Climate change in the area was found to be already precent with 2020’s average temperatures being 1.23°C warmer than in 2011, and that year registering warmer temperatures than what the IPCC’s model forecasted for the area in the year 2080. Adobe was found to have considerably lower levels of embodied emissions associated with its life cycle when compared to cement-based elements. House 1 was calculated to have 49.6% less CO2e embodied emissions per m2 when built with adobe walls, and House 2, 53.9% less CO2e emissions than the same dwellings made with cement. Finally, it was found that with the current climate in the area, dwellings made with cement achieved less time within a comfortable range of temperatures than the same dwellings built with adobe. Nevertheless, considering the increasing temperatures for the area, the same properties that give adobe dwellings an advantage today, could mean that they would require higher volumes of electricity to cool down in the future.
Postsynaptic burst reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputs.
Creators: name: Fuchsberger, Tanja
name: Clopath, Claudia
name: Jarzebowski, Przemyslaw
name: Brzosko, Zuzanna
name: Wang, Hongbing
name: Paulsen, Ole
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Research Advance
Neuroscience
synaptic plasticity
long-term potentiation
eligibility trace
dopamine
neuromodulation
memory
Mouse

description: Peer reviewed: True
description: A fundamental unresolved problem in neuroscience is how the brain associates in memory events that are separated in time. Here, we propose that reactivation-induced synaptic plasticity can solve this problem. Previously, we reported that the reinforcement signal dopamine converts hippocampal spike timing-dependent depression into potentiation during continued synaptic activity (Brzosko et al., 2015). Here, we report that postsynaptic bursts in the presence of dopamine produce input-specific LTP in mouse hippocampal synapses 10 min after they were primed with coincident pre- and post-synaptic activity (post-before-pre pairing; Δt = -20 ms). This priming activity induces synaptic depression and sets an NMDA receptor-dependent silent eligibility trace which, through the cAMP-PKA cascade, is rapidly converted into protein synthesis-dependent synaptic potentiation, mediated by a signaling pathway distinct from that of conventional LTP. This synaptic learning rule was incorporated into a computational model, and we found that it adds specificity to reinforcement learning by controlling memory allocation and enabling both 'instructive' and 'supervised' reinforcement learning. We predicted that this mechanism would make reactivated neurons activate more strongly and carry more spatial information than non-reactivated cells, which was confirmed in freely moving mice performing a reward-based navigation task.
Additional file 1 of Retrospective analysis of pulmonary cryptococcosis and extrapulmonary cryptococcosis in a chinese tertiary hospital
Creators: name: Shi, Jiejun
name: Chen, Jianhua
name: Hu, Liqing
name: Ma, Ada Hoi Yan
name: Hu, Haoxuan
name: Wang, Chuwen
name: Huang, Jiajia
name: Song, Qifa
name: Qian, Guoqing
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Virology

description: Additional file 1.
A non-perturbative study of the evolution of cosmic magnetised sources
Creators: name: Gaspar, I. Delgado
name: Martínez, A. Pérez
name: Piccinelli, G.
name: Sussman, Roberto A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We undertake a hydrodynamical study of a mixture of tightly coupled primordial radiation, neutrinos, baryons, electrons and positrons, together with a gas of already decoupled dark matter WIMPS and an already existing "frozen" magnetic field in the infinite conductivity regime. Considering this cosmic fluid as the source of a homogeneous but anisotropic Bianchi I model, we describe its interaction with the magnetic field by means of suitable equations of state that are appropriate for the particle species of the mixture between the end of the leptonic era and the beginning of the radiation-dominated epoch. Fulfilment of observational bounds on the magnetic field intensity yields a "near FLRW" (but strictly non-perturbative) evolution of the geometric, kinematic and thermodynamical variables. This evolution is roughly comparable to the weak field approximation in linear perturbations on a spatially flat FLRW background of sources in which the frozen magnetic fields are coherent over very large supra-horizon scales. Our approach and results may provide interesting guidelines in potential situations in which non-perturbative methods are required to study the interaction between magnetic fields and the cosmic fluid.
description: Accepted in General Relativity and Gravitation. The final publication will be available at Springer via http://dx.doi.org/10.1007/s10714-015-2004-3
Covariant Space Time Line Elements in the Friedmann Lemaitre Robertson Walker Geometry
Creators: name: Escors, David
name: Kochan, Grazyna
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: Most quantum gravity theories quantize space time on the order of Planck length (lp). Some of these theories, such as loop quantum gravity (LQG), predict that this discreetness could be manifested through Lorentz invariance violations (LIV) over travelling particles at astronomical length distances. However, reports on LIV are controversial, and space discreetness could still be compatible with Lorentz invariance. Here, it is tested whether space quantization on the order of Planck length could still be compatible with Lorentz invariance through the application of a covariant geometric uncertainty principle (GeUP) as a constraint over geodesics in FRW geometries. Space time line elements compatible with the uncertainty principle are calculated for a homogeneous, isotropic expanding Universe represented by the Friedmann Lemaitre Robertson Walker solution to General Relativity (FLRW or FRW metric). A generic expression for the quadratic proper space time line element is derived, proportional to Planck length squared, and dependent on two contributions. The first is associated to the energy time uncertainty, and the second depends on the Hubble function. The results are in agreement with space-time quantization on the expected length orders, according to quantum gravity theories, and within experimental constraints on putative LIV.
description: The manuscript was accepted in Axioms
Additional file 1 of Genome-wide discovery of circulating cell-free DNA methylation biomarkers for colorectal cancer detection
Creators: name: Fang, Qingxiao
name: Yuan, Ziming
name: Hu, Hanqing
name: Zhang, Weiyuan
name: Wang, Guiyu
name: Wang, Xishan
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Virology

description: Additional file 1. Supplementary figures and Table S1.
Figure 1: Schematic representation of mosaic creation mechanisms.; Figure 2: Mosaic formation mechanisms Regularity Index (RI). from Retinal self-organization: a model of retinal ganglion cells and starburst amacrine cells mosaic formation
Creators: name: de Montigny, Jean
name: Sernagor, Evelyne
name: Bauer, Roman
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Neuroscience
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: Different time points are represented (linked by black arrows), illustrating mosaic formation mechanisms. Diffusion of chemical substances are represented by a translucent circle around the diffusing cell. For clarity purpose, only three cell types are represented. A: Cell fate. After differentiation, cells start secreting a chemical cue preventing neighbouring cells to differentiate into the same cell type. This mechanism continues until all cells are differentiated. B: Cell migration. Each cell type chemical substance act as a homotypic repulsive cue, triggering tangential migration. Cellular migrations are represented by thin grey arrows. C: Cell death. Chemical substances act as homotypic developmental cues triggering apoptosis if the chemical concentration is higher than a defined threshold.; Final RI values for each mosaic formation mechanisms (CF: cell fate; CD: cell death; CM: cell migration) individually or in combination. The dashed line represents the RI of a random distribution (RI=1.9). N=8 in each condition. *** for p>0.001 and n.s. for p<0.05 with a Mann-Whitney U test.
Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes.
Creators: name: Wei, Wei
name: Schon, Katherine R
name: Elgar, Greg
name: Orioli, Andrea
name: Tanguy, Melanie
name: Giess, Adam
name: Tischkowitz, Marc
name: Caulfield, Mark J
name: Chinnery, Patrick F
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/631/208/212
/692/420/2489/144
/631/67/69
/631/443/319/333
/45/23
article

description: DNA transfer from cytoplasmic organelles to the cell nucleus is a legacy of the endosymbiotic event-the majority of nuclear-mitochondrial segments (NUMTs) are thought to be ancient, preceding human speciation1-3. Here we analyse whole-genome sequences from 66,083 people-including 12,509 people with cancer-and demonstrate the ongoing transfer of mitochondrial DNA into the nucleus, contributing to a complex NUMT landscape. More than 99% of individuals had at least one of 1,637 different NUMTs, with 1 in 8 individuals having an ultra-rare NUMT that is present in less than 0.1% of the population. More than 90% of the extant NUMTs that we evaluated inserted into the nuclear genome after humans diverged from apes. Once embedded, the sequences were no longer under the evolutionary constraint seen within the mitochondrion, and NUMT-specific mutations had a different mutational signature to mitochondrial DNA. De novo NUMTs were observed in the germline once in every 104 births and once in every 103 cancers. NUMTs preferentially involved non-coding mitochondrial DNA, linking transcription and replication to their origin, with nuclear insertion involving multiple mechanisms including double-strand break repair associated with PR domain zinc-finger protein 9 (PRDM9) binding. The frequency of tumour-specific NUMTs differed between cancers, including a probably causal insertion in a myxoid liposarcoma. We found evidence of selection against NUMTs on the basis of size and genomic location, shaping a highly heterogenous and dynamic human NUMT landscape.
description: Wellcome, MRC, UKRI, NIHR
Additional file 1 of Serum IL-23 significantly decreased in obese patients with psoriatic arthritis six months after a structured weight loss intervention
Creators: name: Landgren, A. J.
name: Jonsson, C. A.
name: Bilberg, A.
name: Eliasson, B.
name: Torres, L.
name: Dehlin, M.
name: Jacobsson, L. T. H.
name: Gjertsson, I.
name: Larsson, I.
name: Klingberg, E.
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health
subject: Computational Biology

description: Additional file 1: Supplementary table 1. Spearman correlations for ∆IL-23, ∆IL-17, ∆leptin and other analytes, between baseline and month 6 in patients with psoriatic arthritis, n=41. Supplementary figure 1. Scatterplots of the correlations between ΔIL-23 and a) Δleptin, b) ΔDAS28CRP, at month 6 in patients with psoriatic arthritis.
Mega-Event Organization Considering Safety, Security and Resilience
Creators: name: Atun Girgin, Funda
name: Edizel Tasci, Ozlem
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2019

description: Cities become globally significant and attract national and international interest from all over the world with the help of mega-events, such as World EXPO and the Olympic Games. Mega-events highly require the involvement of various actors working together for the same overall purpose, although these actors have the responsibility of diverse target groups and require to use different resources. In his paper, we aim to understand the role of organizations in mega-events in relation to the socio-technical systems they operate. We consider security, safety and resilience articulated in six areas: planning, construction of the site, training, collaboration, communication and legacy, in three different time slots: before, during and after the event. Results include insights to enhance multi-organizational culture-based practice. The field studies conducted in Milan in 2015 and 2016 on Milan World EXPO 2015, and in London in 2012 and 2016 on the London Olympic and Paralympic Games 2012. The research findings are based on the experience of the real actors involved in these two events. The findings suggest several courses of action for decision-makers and emergency planners to safety and security design strategies that can facilitate resilience as a legacy of a mega-event.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 12 No 3 (2019): The Times They Are a-Changin'
One underlying mechanism for two piezoelectric effects in the octonion spaces
Creators: name: Weng, Zi-Hua
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: The paper aims to apply the algebra of octonions to explore the contributions of external derivative of electric moments and so forth on the induced electric currents, revealing a few major influencing factors relevant to the direct and inverse piezoelectric effects. J. C. Maxwell was the first to adopt the algebra of quaternions to describe the physical quantities of electromagnetic fields. The contemporary scholars utilize the quaternions and octonions to research the physical properties of electromagnetic and gravitational fields. The application of octonions is able to study the physical quantities of electromagnetic and gravitational fields, including the octonion field strength, field source, linear moment, angular moment, torque and force. When the octonion force is equal to zero, it is capable of achieving eight independent equations, including the force equilibrium equation, fluid continuity equation, current continuity equation, and second-precession equilibrium equation and others. One of inferences derived from the second-precession equilibrium equation is that the electric current and derivative of electric moments are able to excite each other. The external derivative of electric moments can induce the electric currents. Meanwhile the external electric currents are capable of inducing the derivative of electric moments. The research states that this inference can be considered as the underlying mechanism for the direct and inverse piezoelectric effects. Further the second-precession equilibrium equation is able to predict several new influencing factors of direct and inverse piezoelectric effects.
description: Latex
Optimization of a Non-arsenic Iron-based Superconductor for Wire Fabrication
Creators: name: Mitchell, Jonathan E.
name: Hillesheim, Daniel A.
name: Bridges, Craig A.
name: Paranthaman, M. Parans
name: Gofryk, Kris
name: Rindfleisch, Mike
name: Tomsic, Mike
name: Sefat, Athena S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report on the optimization of synthesis of iron-selenide (non-arsenic) superconducting powders that are based on '122' composition, with optimal Tc = 38 K and Jc = 10^5 A/cm2 (4 K). We also report on the wire proof-of concept for these materials, by producing ~ 40 ft of wire that produce Ic. The 122 selenides are more difficult to synthesize and have more complex crystal structures compared to '11' selenides (FeSe and FeSe1-xTex), but they do offer higher Tc and might provoke a natural extension for 11 work.
description: 13 pages, 7 figures; Submitted to SuST
Defining urban green infrastructure role in analysis of climate resiliency in cities based on landscape ecology theories
Creators: name: Shirgir, Elmira
name: Kheyroddin, Reza
name: Behzadfar, Mostafa
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2019

description: Cities are exposed to the risk of climate change and as a result, are very vulnerable. In recent years, to face the challenges caused by the climate change, the notion of climate resilience and specifically, urban ecological resilience, has been studied. Climate resilience is in focus of this paper and a subcategory of urban ecological resilience, which is defined as the urban resilience to the climate change. Also, urban green infrastructure has an established role as one of the strategies for adapting to climate change and for developing and promoting climate resilience in cities. Given the theoretical gap existing in this field, this question arises: "How and based on which features of the green infrastructure can we assess and analyze the climate resilience in a city?” To answer this question, the landscape ecology principles and relationship between these principles and the green infrastructure in the cities were used. The relationship was developed in the Yousef Abad neighborhood of Tehran and was qualitatively tested using the aerial images, field surveys and preparation of basic and analytical GIS maps. Finally, the "effective factors in assessing the climate resilience in cities using the urban green infrastructures based on landscape ecology" were obtained.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 12 No 3 (2019): The Times They Are a-Changin'
Walking and talking: The effect of smartphone use and group conversation on pedestrian speed
Creators: name: Walsh, Lexie Reynolds
name: Xian, Tingsen (Tim)
name: Levinson, David Matthew
name: Rayaprolu, Hema Sharanya
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2019

description: Distracted walking due to smartphone use is on the rise resulting in growing concern over pedestrian safety and well-being. Our study measured the walking speeds of pedestrian groups differentiated by their smartphone use in two different environments - a wide pedestrian bridge at a university, and a narrow footpath on a busy commercial street. The results show that groups of people, phone users, and often followers of phone users, walk significantly slower than solo walkers uninfluenced by phone. Especially on the narrow street, people in groups and phone users are seen to not only slow themselves down but also slow the people walking behind them.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 12 No 3 (2019): The Times They Are a-Changin'
Additional file 1 of Using a theory-informed approach to guide the initial development of a post-tuberculosis care package in British Columbia, Canada
Creators: name: Romanowski, Kamila
name: Cook, Victoria Jane
name: Gilbert, Mark
name: Johnston, James Cameron
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. GUIDED – a guideline for reporting for intervention development studies.
Mass-energy connection without special relativity
Creators: name: D'Abramo, Germano
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: In 1905, Einstein carried out his first derivation of the mass-energy equivalence by studying in different reference frames the energy balance of a body emitting electromagnetic radiation and assuming special relativity as a prerequisite. In this paper, we prove that a general mass-energy relationship can be derived solely from very basic assumptions, which are the same made in Einstein's first derivation but completely neglecting special relativity. The general mass-energy relationship turns to a mass-energy equivalence when is applied to the case of a body emitting energy in the form of electromagnetic waves. Our main result is that if the core logic behind Einstein's approach is sound, then the essence of the mass-energy equivalence can be derived without special relativity. We believe that our heuristic approach, although not capable of giving the exact mathematical formula for the mass-energy equivalence, may represent a useful addition to the general discussion on the matter at the graduate level. Our finding suggests that the connection between mass and energy is at a deeper level and comes before any full-fledged physical theory.
description: 10 pages, 2 figures
High speed rail and airport. Future scenarios in Marco Polo Airport in Venice
Creators: name: Pucci, Paola
name: Lanza, Giovanni
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2019

description: This paper introduces an analysis of the possible extension of the catchment area of the Venice Marco Polo Airport, due to the implementation of a direct rail connection and the completion of the high speed/high capacity railway between Milan and Trieste. Both interventions are expected to generate an increase in the accessibility thresholds by rail to the airport. By constructing different scenarios based on the analysis of the evolution in mobility trends and settling patterns, retraced considering both demographic dynamics and large scale projects, this article estimates the effects generated by the new railway connections in terms of extension of the Marco Polo airport’s catchment area and the related impacts on air traffic, in terms of potential new passengers.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 12 No 3 (2019): The Times They Are a-Changin'
Continuous joint measurement and entanglement of qubits in remote cavities
Creators: name: Motzoi, Felix
name: Whaley, K. Birgitta
name: Sarovar, Mohan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present a first-principles theoretical analysis of the entanglement of two superconducting qubits in spatially separated microwave cavities by a sequential (cascaded) probe of the two cavities with a coherent mode, that provides a full characterization of both the continuous measurement induced dynamics and the entanglement generation. We use the SLH formalism to derive the full quantum master equation for the coupled qubits and cavities system, within the rotating wave and dispersive approximations, and conditioned equations for the cavity fields. We then develop effective stochastic master equations for the dynamics of the qubit system in both a polaronic reference frame and a reduced representation within the laboratory frame. We compare simulations with and analyze tradeoffs between these two representations, including the onset of a non-Markovian regime for simulations in the reduced representation. We provide conditions for ensuring persistence of entanglement and show that using shaped pulses enables these conditions to be met at all times under general experimental conditions. The resulting entanglement is shown to be robust with respect to measurement imperfections and loss channels. We also study the effects of qubit driving and relaxation dynamics during a weak measurement, as a prelude to modeling measurement-based feedback control in this cascaded system.
description: 17 pages, 8 figures. Published version
Frequency shifts in gravitational resonance spectroscopy
Creators: name: Baeßler, S.
name: Nesvizhevsky, V. V.
name: Pignol, G.
name: Protasov, K. V.
name: Rebreyend, D.
name: Kupriyanova, E. A.
name: Voronin, A. Yu.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum states of ultracold neutrons in the gravitational field are to be characterized through gravitational resonance spectroscopy. This paper discusses systematic effects that appear in the spectroscopic measurements. The discussed frequency shifts, which we call Stern-Gerlach shift, interference shift, and spectator state shift, appear in conceivable measurement schemes and have general importance. These shifts have to be taken into account in precision experiments.
Reviews Pages: The Times They are A-Changin’ 2(2019)
Creators: name: Angiello, Gennaro
name: Gaglione, Federica
name: Guida, Carmen
name: Morosini, Rosa
name: Tulisi, Andrea
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2019

description: Starting from the relationship between urban planning and mobility management, TeMA has gradually expanded the view of the covered topics, always remaining in the groove of rigorous scientific in-depth analysis. During the last two years a particular attention has been paid on the Smart Cities theme and on the different meanings that come with it. The last section of the journal is formed by the Review Pages. They have different aims: to inform on the problems, trends and evolutionary processes; to investigate on the paths by highlighting the advanced relationships among apparently distant disciplinary fields; to explore the interaction’s areas, experiences and potential applications; to underline interactions, disciplinary developments but also, if present, defeats and setbacks. Inside the journal the Review Pages have the task of stimulating as much as possible the circulation of ideas and the discovery of new points of view. For this reason the section is founded on a series of basic’s references, required for the identification of new and more advanced interactions. These references are the research, the planning acts, the actions and the applications, analysed and investigated both for their ability to give a systematic response to questions concerning the urban and territorial planning, and for their attention to aspects such as the environmental sustainability and the innovation in the practices. For this purpose the Review Pages are formed by five sections (Web Resources; Books; Laws; Urban Practices; News and Events), each of which examines a specific aspect of the broader information storage of interest for TeMA.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 12 No 2 (2019): The Times They Are a-Changin'
Superconductivity in Semimetallic Bi3O2S3
Creators: name: Li, L.
name: Parker, D.
name: Babkevich, P.
name: Yang, L.
name: Ronnow, H. M.
name: Sefat, A. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Here we report further investigation on the thermodynamic, and transport properties, and the first assessment of theoretical calculations for the BiS2-layered Bi3O2S3 superconductor. The polycrystalline sample is synthesized with the superconducting transition temperature of Tc_onset = 5.75 K, that drops to 3.3 K by applying hydrostatic pressure of 6 kbar. Density-of-states calculations give substantial hybridization between Bi, O and S, with the largest Bi component at DOS, which supports the idea that BiS2 layer is relevant for producing electron-phonon coupling. The electron charge carrier concentration of only 1.5 x 10^19 cm-3 for Bi3O2S3 is additionally suggestive of strong electron-phonon interaction in Bi-O-S system. The analysis of Seebeck coefficient results strongly suggests that Bi3O2S3 is a semimetal. In fact, the semimetallic or narrow band gap behavior may be general in the BiS2-layered class of materials, including that of Bi4O4S3.
description: 3 figures; submitted to PRB