cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Inhalative Nanoparticulate CpG Immunotherapy in Severe Equine Asthma: An Innovative Therapeutic Concept and Potential Animal Model for Human Asthma Treatment
Creators: name: Klier, John
name: Fuchs, Sebastian
name: Winter, Gerhard
name: Gehlen, Heidrun
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: asthma
subject: immunotherapy
subject: allergy
subject: nanoparticle
subject: CpG
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten

description: Severe equine asthma is the most common globally widespread non-infectious equine respiratory disease (together with its mild and moderate form), which is associated with exposure to hay dust and mold spores, has certain similarities to human asthma, and continues to represent a therapeutic problem. Immunomodulatory CpG-ODN, bound to gelatin nanoparticles as a drug delivery system, were successfully administered by inhalation to severe equine asthmatic patients in several studies. It was possible to demonstrate a significant, sustained, and allergen-independent one-to-eight-week improvement in key clinical parameters: the arterial partial pressure of oxygen, the quantity and viscosity of tracheal mucus, and neutrophilic inflammatory cells in the respiratory tracts of the severe equine asthmatic subjects. At the immunological level, an upregulation of the regulatory antiallergic and anti-inflammatory cytokine IL-10 as well as a downregulation of the proallergic IL-4 and proinflammatory IFN-γ in the respiratory tracts of the severe equine asthmatic patients were identified in the treatment groups. CD4+ T lymphocytes in the respiratory tracts of the asthmatic horses were demonstrated to downregulate the mRNA expression of Tbet and IL-8. Concentrations of matrix metalloproteinase-2 and -9 and tissue inhibitors of metalloproteinase-2 were significantly decreased directly after the treatment as well as six weeks post-treatment. This innovative therapeutic concept thus opens new perspectives in the treatment of severe equine asthma and possibly also that of human asthma.
title: Κωδικοποίηση διαύλου για την αποφυγή υποκλοπών
title: Coding for the wiretap channel
Creators: name: Κωστα Αντζελα
Publisher: name: Technical University of Crete
Year: 2015

description: In this work we consider the problem of achieving information-theoretic security with practical coding complexity. Specifically, we consider a transmitter, a receiver, and an eavesdropper where the communication channels between the transmitter and the receiver and between the transmitter and the eavesdropper are both binary erasure channels. The objective is the development of a practical coding scheme that attains maximum transmission rate between the transmitter and the receiver and,  simultaneously, complete protection of the transmitted data from the eavesdropper.

We utilize polar codes which are known to achieve the capacity of any symmetric binary-input discrete memoryless channel. We focus on the binary erasure channel and present the pertinent polar encoding and decoding algorithms. Finally, we show how polar coding can be used for the wire-tap binary erasure channel, achieving maximum transmission rate and complete protection.
Willi von Gonzenbach: (Prof.für Hygiene und Bakteriologie ETH)
Creators: name: Gonzenbach, Wilhelm <>
Publisher: name: ETH Zurich
Year: 1985
Subjects: HANDSCHRIFTENVERZEICHNISSE + HANDSCHRIFTENKATALOGE
Gonzenbach, Wilhelm von
MANUSCRIPT LITERATURE BIBLIOGRAPHIES
info:eu-repo/classification/ddc/610
info:eu-repo/classification/ddc/570
Medical sciences, medicine
Life sciences

description: Handschriften und Autographen der ETH-Bibliothek, 38
title: Εγκατάσταση πειραματικής θερμοκηπιακής καλλιέργειας τομάτας και μελέτη επίδρσης του συμβιωτικού μύκητα Trichoderma harzianum υπό συνθήκες αλάτωσης
Creators: name: Βαγκνερ Καρλ-Μπαζιλ
Publisher: name: Technical University of Crete
Year: 2016

description: Η εργασία πραγματεύεται τη μελέτη θερμοκηπιακής καλλιέργειας της τομάτας (Solanum lycopersicum) «Ελπίδα» και την επίδραση της εφαρμογής του συμβιωτικού μύκητα Trichoderma harzianum (TH) υπό συνθήκες άρδευσης με νερό μέσης και υψηλής αγωγιμότητας. Για τη διερεύνηση των παραπάνω, σχεδιάστηκε και υλοποιήθηκε μια πειραματική θερμοκηπιακή διάταξη στο Πολυτεχνείου Κρήτης (ΠΚ) που προσομοιώνει τις καλλιεργητικές πρακτικές της περιοχής του Τυμπακίου (ΝΔ του Ν. Ηρακλείου Κρήτης) όπου παρουσιάζεται το πρόβλημα της υφαλμύρινσης υδροφόρου ορίζοντα. Το έδαφος προήλθε από την περιοχή μελέτης και οι τιμές ηλεκτρικής αγωγιμότητας (EC) του νερού άρδευσης ήταν παρόμοιες με αυτές που συναντούνται στο πεδίο. Η διάταξη του πειράματος χωρίστηκε σε 4 μεταχειρίσεις που ανά δύο αρδεύονταν με αντιπροσωπευτικές τιμές μέσης και υψηλής EC στα 1,1 dS/m και 3,5 dS/m, αντίστοιχα, και ανά δύο είχαν παρουσία ή απουσία μύκητα TH στο ριζικό τους σύστημα. Κατά τη διάρκεια του πειράματος μελετήθηκαν η ανάπτυξη και η εξέλιξη των φυτών και υπολογίστηκε ο δείκτης συγκομιδής. Επιπλέον καταγράφηκε το ύψος της συνολικής και εμπορεύσιμης παραγωγής. Όσον αφορά τους καρπούς, εκτιμήθηκε η ομοιομορφία τους όπως και η ποιότητα τους μέσω χημικών αναλύσεων. Ακόμα, πραγματοποιήθηκαν τέσσερις εδαφικές δειγματοληψίες για τη διερεύνηση της πορείας βασικών παραμέτρων που σχετίζονται με την αλάτωση των εδαφών, όπως EC, SAR, pH και η παρουσία μετάλλων, η εδαφική υγρασία και η πορεία των θρεπτικών. Τα αποτελέσματα που προκύπτουν αποτυπώνουν τις απώλειες στην τοπική παραγωγή αλλά και τις επιπτώσεις στο έδαφος λόγω της αλάτωσης. Σχετικά με την εφαρμογή του TH, τα αποτελέσματα είναι ενθαρρυντικά, ιδιαίτερα σε σχέση με την πρώιμη παραγωγή, την ομοιομορφία των καρπών, αλλά και την κατάστασης του εδάφους μετά το πέρας της καλλιέργειας, όπου υπήρξε βελτίωση του δείκτη SAR πάνω από 35%. Τα αποτελέσματα του πειράματος χρησιμοποιούνται για την ανάδειξη του προβλήματος την αλάτωσης καθώς και για την προώθηση μεθόδων αειφορικής καλλιέργειας στην περιοχή του Τυμπακίου. Στα πλαίσια της εργασία έγιναν 4 παρουσιάσεις σε διεθνή επιστημονικά συνέδρια.
Microplastics in Namibian river sediments – a first evaluation
Creators: name: Faulstich, Leona
name: Prume, J. A.
name: Arendt, Robert
name: Reinhardt-Imjela, Christian
name: Chifflard, P.
name: Schulte, Achim
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Microplastics
subject: Fluvial sediments
subject: Namibia
subject: Ephemeral rivers
subject: FTIR spectroscopy
subject: 500 Naturwissenschaften und Mathematik::550 Geowissenschaften, Geologie::550 Geowissenschaften

description: The African continent is rarely the focus of microplastics research, although the ubiquity of microplastics in the environment is undisputed and still increasing. Due to the high production and use of plastic products and the partial lack of recycling systems in many parts of the African continent, it can be assumed that microplastic particles are already present in limnic and terrestrial ecosystems. Few studies, mainly from South Africa and the Northern African region, show a contamination with microplastics, especially in marine environments. This study aims to explore the presence and composition of microplastics in fluvial sediments of the major catchments in Namibia with a regional focus on the Iishana system in Northern Namibia, as one of the most densely populated areas in the country. In March 2019 and March 2021, at the end of the rainy seasons, sediments from the Iishana system and of the largest river catchments were sampled. Extraction was performed by density separation using the Microplastic Sediment Separator (MPSS) with the separation solution sodium chloride (density of 1.20 g/cm3). The particle size was determined by filtration and fractionation, and the polymer type by measurement with ATR-FTIR spectroscopy (minimum particle size 0.3 mm). Microplastics were found in the sediments of each river system, most of the particles in the Iishana system (average of 13.2 particles/kg dry weight). The perennial, the ephemeral rivers, and the Iishana system are similar concerning polymer type and particle size. Polyethylene and polypropylene were the dominant polymer types. Most of the particles were found in the size fractions 0.3 – 0.5 mm and 0.5 – 1.0 mm. The particles were found mainly as fragments and films, the majority transparent and brown.
Bartel L. Van der Waerden 1903-1996: ( Titel der Diplomarbeit: Die Briefsammlung B.L. Van der Waerden)
Creators: name: Jakob, Barbara
name: Waerden, Bartel L. <>
Publisher: name: ETH Zurich
Year: 1985
Subjects: subject: BRIEFE + BRIEFWECHSEL (DOKUMENTENTYP)
subject: HOCHSCHULLEHRKÖRPER (HOCHSCHULWESEN)
subject: MATHEMATIK
subject: SCHWEIZ (MITTELEUROPA). SCHWEIZERISCHE EIDGENOSSENSCHAFT
subject: HANDSCHRIFTENVERZEICHNISSE + HANDSCHRIFTENKATALOGE
subject: NIEDERLANDE (WESTEUROPA). KÖNIGREICH DER NIEDERLANDE
subject: Waerden, Bartel L. van der
subject: LETTERS + CORRESPONDENCE (DOCUMENT TYPES)
subject: UNIVERSITY TEACHERS (HIGHER EDUCATION)
subject: MATHEMATICS
subject: SWITZERLAND (CENTRAL EUROPE). SWISS CONFEDERATION
subject: MANUSCRIPT LITERATURE BIBLIOGRAPHIES
subject: NETHERLANDS (WEST EUROPE). KINGDOM OF THE NETHERLANDS
subject: info:eu-repo/classification/ddc/510
subject: Mathematics
subject: FOS: Mathematics

description: Handschriften und Autographen der ETH-Bibliothek, 57
Paternal deprivation and female biparental family rearing induce dendritic and synaptic changes in octodon degus : I. Medial prefrontal cortex
Creators: name: Tony, Schultz
name: Bock, Jörg
name: Braun, Anna Katharina
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2020
Subjects: subject: Dendritic spines
subject: Prefrontal cortex
subject: Paternal deprivation
subject: Family structure
subject: Sex difference
subject: Pyramidal neuron
subject: 570

description: In most mammalian species parent-offspring interactions during early life periods primarily comprise social contacts with the mother, whereas the role of males in parental care is one of the most overlooked and understudied topics. The present study addressed the hypothesis that the complete deprivation of paternal care delays or permanently retards synaptic connectivity in the brain, particularly in the medial prefrontal cortex (mPFC) of the offspring in a sex-specific manner. Another aim of this study was to address the question whether and in which way replacing the father with a female caregiver (in our experiments the “aunt”) can “buffer” the detrimental effects of paternal deprivation on neuronal development. The comparison of: (a) single mother rearing; (b) biparental rearing by father and mother; and (c) biparental rearing by two female caregivers revealed that: (i) paternal care represents a critical environmental factor for synaptic and dendritic development of pyramidal neurons in the vmPFC of their offspring; (ii) a second female caregiver (“aunt”) does not “buffer” the neuronal consequences of paternal deprivation; and that (iii) neuronal development in the vmPFC is differentially affected in male and female offspring in response to different family constellations.
agroBRIDGES "Hear my voice" Tool content: Crowdfunding guide
Creators: name: Eirini Efthymiadou
name: Malliopoulos, Georgios
Publisher: name: Zenodo
Year: 2023

description: Crowdfunding is an alternative method of financing that could be a useful tool for agri-food businesses involved or willing to become involved in Short Food Supply Chains (SFSCs). This community-supported method of financing is popular in other sectors such as art, technology and others, but small-scale farmers might not yet be familiar with crowdfunding. The "Hear My Voice" tool (available in the agroBRIDGES Toolbox) provides a short guide with introductory information about crowdfunding methods, platforms, examples from the agri-food industry and suggested platforms to support small-scale farmers and producers. 
The Crowdfunding guide is available in 12 European languages, as indicated in the filenames below:

agroBRIDGES_Hear_My_Voice_Denmark_Crowdfunding-Guide_20230714_v2
agroBRIDGES_Hear_My_Voice_English_Crowdfunding-Guide_20230901_v1
agroBRIDGES_Hear_My_Voice_Finland_Crowdfunding-Guide_20230901_v1
agroBRIDGES_Hear_My_Voice_France_Crowdfunding-Guide_20230901_v1
agroBRIDGES_Hear_My_Voice_Greece_Crowdfunding-Guide_20230901_v1
agroBRIDGES_Hear_My_Voice_Italy_Crowdfunding-Guide_20230901_v1
agroBRIDGES_Hear_My_Voice_Latvia_Crowdfunding-Guide_20230901_v1
agroBRIDGES_Hear_My_Voice_Lithuania_Crowdfunding-Guide_20230901_v1
agroBRIDGES_Hear_My_Voice_Netherlands_Crowdfunding-Guide_20230901_v1
agroBRIDGES_Hear_My_Voice_Poland_Crowdfunding-Guide_20230901_v1
agroBRIDGES_Hear_My_Voice_Spain_Crowdfunding-Guide_20230901_v1
agroBRIDGES_Hear_My_Voice_Turkey_Crowdfunding-Guide_20230901_v1
title: Κατασκευή και λειτουργία συστήματος εκφύσησης εργαστηριακής κλίμακας, για την εξυγίανση υπόγειων υδάτων από πτητικούς πετρελαϊκούς ρύπους (BTEX)
title: Construction and operation of lab-scale air-stripping system for groundwater treatment from volatile petroleum pollutants (BTEX)
Creators: name: Γαρδελης Αλεξανδρος
Publisher: name: Technical University of Crete
Year: 2016

description: Η συγκεκριμένη μελέτη περιλαμβάνει ως πρώτο μέρος την κατασκευή μιας διάταξης εκφύσησης πειραματικών διαστάσεων. Η στήλη από πλαστικό (Plexiglas), δεν σχεδιάστηκε και δημιουργήθηκε από την αρχή, αλλά τροποποιήθηκε ήδη υπάρχουσα στήλη, με τρόπο ώστε να εξυπηρετεί όλες τις παραμέτρους της διεργασίας της απογύμνωσης των οργανικών ρύπων από το νερό. Η εκφύσηση (air stripping), αποτελεί μια φυσική διαδικασία διαχωρισμού των ρύπων από την υγρή φάση στην αέρια και ταυτόχρονα είναι και οικονομική. Οι ουσίες που προτιμώνται για επεξεργασία είναι ιδιαίτερα πτητικές έτσι ώστε να απομακρυνθούν με ευκολία. Χρησιμεύει ιδιαίτερα για μεγάλες συγκεντρώσεις καθώς παρουσιάζει μεγάλα ποσοστά απομάκρυνσης (99%) με  μικρό κόστος.
Στο δεύτερο μέρος της μελέτης, σκοπός υπήρξε η επιτυχής απομάκρυνση 2 διαφορετικών συγκεντρώσεων οργανικών ρύπων (BTEX) από υδατικό διάλυμα και η εξέταση της απόδοσης λόγω της παρουσίας αέρα. Χρησιμοποιήθηκαν ρεαλιστικές τιμές συγκέντρωσης, που συναντώνται σε υπόγεια νερά ρυπασμένων περιοχών, 2 και 8 ppm αντίστοιχα, καθώς και 2 διαφορετικά υλικά πλήρωσης της στήλης, λεπτόκοκκο (<4mm) και χονδρόκοκκο χαλίκι (>4mm). Τα αποτελέσματα επίσης περιλάμβαναν, σύγκριση της απόδοσης απομάκρυνσης του κάθε υλικού για καθεμιά από τις 2 συγκεντρώσεις και της απόδοσης των πληρωτικών υλικών μεταξύ τους. Επιπλέον, εξετάστηκε ο επηρεασμός στην απόδοση της εκφύσησης λόγω διαφορετικής συγκέντρωσης. Το εύρος των τελικών απομακρύνσεων  που παρατηρήθηκε κατά μέσο όρο ήταν από 60% έως και 99%. Η επίδραση του αέρα ήταν καθοριστική για την επίτευξη των παραπάνω απομακρύνσεων, ωστόσο υψηλές ήταν και οι απώλειες στο σύστημα χωρίς την παροχή αέρα. Τέλος, οι τελικές συγκεντρώσεις των ρύπων ΒΤΕΧ συγκρίθηκαν με τα επιτρεπτά όρια ρύπανσης και διαπιστώθηκε ότι το 90% των μετρήσεων ανταποκρίθηκαν με επιτυχία.
A Constitutively Active Cytokinin Receptor Variant Increases Cambial Activity and Stem Growth in Poplar
Creators: name: Riefler, Michael
name: Brügmann, Tobias
name: Fladung, Matthias
name: Schmülling, Thomas
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: biomass
subject: cambium
subject: cytokinin
subject: poplar
subject: plant growth
subject: 500 Naturwissenschaften und Mathematik::580 Pflanzen (Botanik)::580 Pflanzen (Botanik)
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: The cambial meristem is responsible for bark and wood formation in woody plants. The activity of the cambial meristem is controlled by various factors; one of them is the plant hormone cytokinin. Here, we have explored different approaches to genetically engineering cambial activity in poplar plants by the ectopic expression of a cytokinin biosynthesis gene with enhanced activity (named ROCK4) or of a gene encoding a constitutively active cytokinin receptor variant (ROCK3). Both genes are derived from Arabidopsis thaliana and were expressed in poplar trees under the control of their own promoter or the cambium-specific pHB8 promoter. pIPT3:ROCK4- and pHB8:ROCK4-expressing plants were smaller than wild-type plants and formed more lateral branches; pHB8:ROCK4 transgenic plants additionally showed an increased stem diameter. In contrast, pAHK3:ROCK3- and pHB8:ROCK3-expressing plants grew taller than wild type without an altered branching pattern and formed more cambial cells, leading to increased radial stem growth. The effectivity of ROCK3 when expressed in either secondary phloem cells or in cambial cells is consistent with a dual, tissue-autonomous and non-autonomous activity of cytokinin in regulating cambial activity. We propose ROCK3 as a novel gene to enhance biomass formation in woody plants.
title: Ανάλυση φυσικού αναγλύφου του νομού Χανίων με χρήση γεωγραφικών συστημάτων πληροφοριών
title: Analysis of relief of Chania using geographic information systems
Creators: name: Γεωργιοπουλου Χρυσανθη
Publisher: name: Technical University of Crete
Year: 2017

description: Η παρούσα διπλωματική εργασία με θέμα «Ανάλυση Φυσικού Αναγλύφου του Νομού Χανίων με Χρήση Γεωγραφικών Συστημάτων Πληροφοριών» έχει ως σκοπό την ανάλυση των υψομέτρων, των κλίσεων, των εκθέσεων και των σκιάσεων στο νομό Χανίων, καθώς και της ορατότητα από συγκεκριμένες θέσεις παρατήρησης.

Αρχικά γίνεται αναφορά στα Γεωγραφικά Συστήματα Πληροφοριών και πιο συγκεκριμένα στο ArcGIS το οποίο χρησιμοποιήθηκε, τις λειτουργίες τους και τη συμβολή τους στην ανάλυση αναγλύφου. Έπειτα οριοθετείται η περιοχή μελέτης και δίνονται γενικές πληροφορίες για τη γεωγραφία, την χλωρίδα και την πανίδα της. Με βάση τις ισοϋψείς καμπύλες (γραμμές του εδάφους που όλα τα σημεία της κάθε μιας έχουν το ίδιο υψόμετρο ) δημιουργείται το Ψηφιακό Μοντέλο Υψομέτρων σε μορφή ΤΙΝ αλλά και raster.Στη συνέχεια αφού γίνει μελέτη και καταγραφή των αλγορίθμων για την εξαγωγή των κλίσεων, των εκθέσεων, των σκιάσεων και της ορατότητας γίνεται εφαρμογή στο νομό Χανίων. Τέλος παρουσιάζονται οι τελικοί χάρτες για κάθε δήμο που προέκυψαν από την εφαρμογή και τα συμπεράσματα για το ανάγλυφο του νομού καθώς και για το πώς επηρεάζεται η ορατότητα.
description: This thesis entitled “Analysis of Relief of Chania Using Geographic Information Systems” aims to analyze elevation, slope, aspect and hillshade of Chania and the visibility of specific observation points.

Initially referring to Geographic Information Systems, and more specifically in ArcGIS that was used, their functions and their contribution to the relief analysis. After defined the study area and given general information about the geography, flora and fauna. Based on the contour lines (land lines all the points of each have the same elevation) created the Digital Elevation Model in TIN and raster format. Then presents the algorithms used to export slopes, aspects, hillshade and visibility in Chania. Finally presents the final maps for each municipality, and conclusions on the relief and how the visibility is affected.
title: Motorbike protective helmets, construction, testing and its influence on the type and severity of injuries of motorbike accident casualties: a literature review
Creators: name: Obst, Maciej
name: Rzepczyk, Szymon
name: Głowiński, Sebastian
name: Żaba, Czesław
Publisher: name: Publishing House of Poznan University of Technology
Year: 2023

description: Vibrations in Physical Systems, 34(1), 2023118-1 - 2023118-20
Methane Emissions from Livestock Slurry: Effects of Storage Temperature and Changes in Chemical Composition
Creators: name: Hilgert, Julio E.
name: Amon, Barbara
name: Amon, Thomas
name: Belik, Vitaly
name: Dragoni, Federico
name: Ammon, Christian
name: Cárdenas, Aura
name: Petersen, Søren O.
name: Herrmann, Christiane
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: GHG emissions
subject: manure management
subject: pig manure storage
subject: dairy manure storage
subject: biochemical methane potential
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::636 Viehwirtschaft

description: Livestock production contributes to releasing methane into the atmosphere. Liquid manure management offers significant opportunities to reduce these emissions. A better understanding of the factors controlling methane emissions from manure is necessary to select effective mitigation strategies. Our study aimed to identify the influence of storage temperature and the associated change in chemical composition on methane emissions from dairy and fattening pig manure. Storage temperature affects microbial activity and induces changes in chemical composition that are key influences in methane emissions. Dairy and fattening pig manure samples were stored at five different temperatures (5–25 °C) for 90 days in a laboratory-scale experiment to measure the methane production. The chemical composition of the slurry samples was analyzed, and the biochemical methane potential (BMP) tests were performed before and after storage. For pig manure stored at 25 °C and 20 °C, methane emissions accounted for 69.3% and 50.3% of the BMP, respectively. Maximum methane emissions for dairy slurry were observed at 25 °C but remained at a low level. Analyses of the accumulation of volatile fatty acids (VFAs) during storage are presented in few studies, this work revealed a potential inhibition of methane production, where the accumulation of VFAs was most elevated in samples stored at 20 °C and 25 °C. This partly counteracted the increase in methane emissions expected from the higher temperatures. The degree of VFA and dissociated fatty acids accumulation in dairy cattle slurry should be assessed for more accurate estimations of methane emissions from slurry stores.
Intrinsically disordered regions of tristetraprolin and DCP2 directly interact to mediate decay of ARE-mRNA
Creators: name: Maciej, Vincent D.
name: Mateva, Nevena
name: Schwarz, Juliane
name: Dittmers, Theresa
name: Mallick, Megha
name: Urlaub, Henning
name: Chakrabarti, Sutapa
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: tristetraprolin (TTP)
subject: DCP2
subject: ARE-mRNA
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: The RNA-binding protein tristetraprolin (TTP) is a potent activator of mRNA decay, specifically for transcripts bearing AU-rich elements (AREs) in their 3′-untranslated regions. TTP functions as a mediator for mRNA decay by interacting with the decay machinery and recruiting it to the target ARE-mRNA. In this study, we report a weak, but direct interaction between TTP and the human decapping enzyme DCP2, which impacts the stability of ARE transcripts. The TTP–DCP2 interaction is unusual as it involves intrinsically disordered regions (IDRs) of both binding partners. We show that the IDR of DCP2 has a propensity for oligomerization and liquid–liquid phase separation in vitro. Binding of TTP to DCP2 leads to its partitioning into phase-separated droplets formed by DCP2, suggesting that molecular crowding might facilitate the weak interaction between the two proteins and enable assembly of a decapping-competent mRNA–protein complex on TTP-bound transcripts in cells. Our studies underline the role of weak interactions in the cellular interaction network and their contribution towards cellular functionality.
Developments in Marketing Spreads for Agricultural Products in 1960
Creators: name: Marketing Economics Division, Economic Research Service
name: Marketing Economics Division, Economic Research Service
Publisher: name: Unknown
Year: 1961
Subjects: subject: Demand and Price Analysis
subject: Labor and Human Capital
subject: Marketing
subject: FOS: Economics and business
subject: Production Economics

description: Excerpts from the Preface: The FARM-RETAIL SPREAD or marketing margin is an estimate of charges made by marketing agencies for assembling, processing, transporting, and distributing a farm product. It is the difference between the retail price and the farm value. The FARM VALUE is the return to the farmer for farm products equivalent to those bought by the consumer. The Congress in 1955 directed the Department of Agriculture to make special studies of spreads between prices paid by consumers and those received by farmers. The Department has published reports of several of these studies. The reports published in 1960 and early 1961 are summarized in this report, which was prepared for the Subcommittee of the Committee on Appropriations, House of Representatives.
description: Statement Before the Subcommittee of the Committee on Appropriation, House of Representatives, 87th Congress, 1st Session
Konrad Keller: (Professor für spezielle Zoologie ETH)
Creators: name: Keller, Conrad
Publisher: name: ETH Zurich
Year: 1983
Subjects: HANDSCHRIFTENVERZEICHNISSE + HANDSCHRIFTENKATALOGE
Keller, Conrad
HANDSCHRIFTEN (WERTVOLLE SCHRIFTEN)
MANUSCRIPT LITERATURE BIBLIOGRAPHIES
MANUSCRIPTS (RARE BOOKS)
info:eu-repo/classification/ddc/590
Zoological sciences

description: Handschriften und Autographen der ETH-Bibliothek, 12
Additional file 1 of Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer
Creators: name: Huang, Kie Kyon
name: Huang, Jiawen
name: Wu, Jeanie Kar Leng
name: Lee, Minghui
name: Tay, Su Ting
name: Kumar, Vikrant
name: Ramnarayanan, Kalpana
name: Padmanabhan, Nisha
name: Xu, Chang
name: Tan, Angie Lay Keng
name: Chan, Charlene
name: Kappei, Dennis
name: Göke, Jonathan
name: Tan, Patrick
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. Rarefaction curve by sub-sampling full-length reads. Figure S2. Comparison between transcriptome predicted using long-read Iso-seq and short-read RNA-seq. Figure S3. Examples of alternative promoter usage associated with changes in the CDs, detected from mass spectrometry data. Figure S4. Validation of Iso-seq transcripts. Figure S5. Transcription factor enrichment in tumor-specific promoters. Figure S6. Representative meDIP-seq peak enrichment around promoter regions in IM95 and MKN1 cell lines. Figure S7. Bioinformatics workflow used in this study.
Does less working time improve life satisfaction? Evidence from European Social Survey
Creators: name: Shao, Qinglong
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Life satisfaction
subject: Working time
subject: Ordered probit model
subject: Health
subject: Job category
subject: 300 Sozialwissenschaften::300 Sozialwissenschaften, Soziologie::301 Soziologie, Anthropologie

description: Background Worktime is one of the main drivers of life satisfaction, and a balanced distribution of working hours and leisure hours directly impacts feelings of well-being. Based on previous studies, we seek to confirm this relationship in the European context and explore other potential driving forces of life satisfaction. Health condition as the mediating variable is also examined. Methods This article uses an ordered probit model to analyze the impact of working time on life satisfaction using data extracted from the most recent round (wave 10) of the European Social Survey (ESS). Hypotheses are proposed to test the impact of working time on life satisfaction, the mediating effect of health in the worktime–satisfaction nexus, and the effects of social inclusion, social trust, feelings of safety, and digitalization on life satisfaction. Results The results reveal a negative and significant correlation between hours of work and life satisfaction, thus implying that a shorter working week can improve Europeans’ life satisfaction. Health is found to be an important intermediate variable that plays an essential role in the dynamic through which working times influence life satisfaction. Further, we find that those in the middle class prefer to work shorter hours to achieve a higher feeling of satisfaction and that high earners to a lesser extent, while low earners generally show no preference. Employees of private firms are more satisfied with shorter working hours, while satisfaction for those working in public institutions is not affected by changes in hours worked. Finally, we verify the robustness of our estimations by replacing life satisfaction with happiness. Conclusions Working fewer hours contributes to higher life satisfaction in Europe, and health plays an essential mediating role in this relationship. Social inclusion, social trust, feelings of safety and digitalization all play a factor in improving life satisfaction. Compared to other job categories, private sector employees can achieve greater life satisfaction from reducing their total working time.
Long-term effects of bilateral pallidal deep brain stimulation in dystonia: a follow-up between 8 and 16 years
Creators: name: Krause, Patricia
name: Völzmann, S.
name: Ewert, S.
name: Kupsch, A.
name: Schneider, Gerd Helge
name: Kühn, Andrea A.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Dystonia
subject: Pallidal DBS
subject: Long-term effects
subject: DBS and quality of life
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objective: Observational study to evaluate the long-term motor and non-motor effects of deep brain stimulation (DBS) of the globus pallidus internus (GPi) on medically refractory dystonia. Background: Dystonia is a chronic disease affecting mainly young patients with a regular life expectancy and lifelong need for therapy. Pallidal DBS is an established treatment for severe isolated dystonia but long-term data are sparse. Methods: We considered 36 consecutive patients with isolated generalized (n = 14) and cervical/segmental (n = 22) dystonia operated at Charité-University Hospital between 2000 and 2007 in a retrospective analysis for long-term outcome of pallidal DBS. In 19 of these patients, we could analyze dystonic symptoms and disability rated by the Burke–Fahn–Marsden Dystonia Rating scale (BFMDRS) at baseline, short-term (ST-FU, range 3–36 months) and long-term follow-up (LT-FU, range 93–197 months). Quality of life and mood were evaluated using the SF36 and Beck Depression Index (BDI) questionnaires. Results: Patients reached an improvement in motor symptoms of 63.8 ± 5.7% (mean ± SE) at ST-FU and 67.9 ± 6.1% at LT-FU. Moreover, a significant and stable reduction in disability was shown following DBS (54.2 ± 9.4% at ST-FU and 53.8 ± 9.2% at LT-FU). BDI and SF36 had improved by 40% and 23%, respectively, at LT-FU (n = 14). Stimulation-induced adverse events included swallowing difficulties, dysarthria, and bradykinesia. Pulse generator (n = 3) and electrodes (n = 5) were revised in seven patients due to infection. Conclusions: Pallidal DBS is a safe and efficacious long-term treatment for dystonia with sustained effects on motor impairment and disability, accompanied by a robust improvement in mood and quality of life.
Richard J. Büchi (1924-1984)
Creators: name: Büchi, Julius Richard
Publisher: name: ETH Zurich
Year: 1986
Subjects: subject: HANDSCHRIFTENVERZEICHNISSE + HANDSCHRIFTENKATALOGE
subject: Büchi, Julius Richard
subject: MANUSCRIPT LITERATURE BIBLIOGRAPHIES
subject: info:eu-repo/classification/ddc/510
subject: Mathematics
subject: FOS: Mathematics

description: Handschriften und Autographen der ETH-Bibliothek, 64
Gender Marking and Clitic Pronoun Resolution in Simultaneous Bilingual Children
Creators: name: Koukoulioti, Vasiliki
name: Stavrakaki, Stavroula
name: Vomva, Maria
name: Adani, Flavia
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: bilingual acquisition
subject: clitic pronouns
subject: gender
subject: language proficiency
subject: language input
subject: sentence production
subject: sentence processing
subject: Modern Greek
subject: 300 Sozialwissenschaften::370 Bildung und Erziehung::370 Bildung und Erziehung
subject: 400 Sprache::410 Linguistik::410 Linguistik

description: The acquisition of clitics still remains a highly controversial issue in Greek acquisition literature despite the bulk of studies performed. Object clitics have been shown to be early acquired by monolingual children in terms of production rates, whereas only highly proficient bilingual children achieve target-like performance. Crucially, errors in gender marking are persistent for monolingual and bilingual children even when adult-like production rates are achieved. This study aims to readdress the acquisition of clitics in an innovative way, by entering the variable of gender in an experimental design targeting to assess production and processing by bilingual and monolingual children. Moreover, we examined the role of language proficiency (in terms of general verbal intelligence and syntactic production abilities). The groups had comparable performance in both tasks (in terms of correct responses and error distribution in production and reaction times in comprehension). However, verbal intelligence had an effect on the performance of the monolingual but not of the bilingual group in the production task, and bilingual children were overall slower in the comprehension task. Syntactic production abilities did not have any effect. We argue that gender marking affects clitic processing, and we discuss the implications of our findings for bilingual acquisition.
title: Vampires and ape men : a Lacanian reading of British fantasy fiction, 1886-1914
Creators: name: Sharoni, Josephine
name: None
Publisher: name: University of Kent
Year: 2015

description: This thesis offers a close reading from the perspective of Lacanian psychoanalysis of a selection of literary texts published in Britain in the thirty years leading to the outbreak of the First World War in 1914. These works, belonging to different genres – science fiction, gothic and the adventure or quest – are loosely categorized as ‘fantasy’ literature as opposed to the realistic novel or short story. My contention is that it is only in conjunction with a consideration of Jacques Lacan’s ‘return to Freud’, that is, his re-examination of the texts of Sigmund Freud, and the work of contemporary theorists writing in Lacan’s wake, such as Slavoj Žižek and Mladen Dolar, that the significance of the fanciful plots and devices appearing in the texts emerges. My starting point is the resemblance which the plot of each of these works bears to that of Freud’s Totem and Taboo, published in 1913, which tells of the killing of a primal father. What might be labelled as the return of the primal father, a violent and obscene figure who must be killed again (whereas for Freud this was a unique event which occurred at the beginning of human time), appears in a period when ‘modern’ Britain is coming into a being, that is, an industrialized, urbanized, literate democracy. It can be seen that the re-appearance of this evil primal father figure follows the demise of traditional forms of authority of the agrarian society, that of the ‘everyday’ father, the aristocracy and the church, and concurrently, the increasing dominance of scientific discourse and technology. In this and in further ways which will be discussed in the thesis, the texts bring to light the function of apparently obsolete symbolic frameworks and the corresponding deficiency in modern paradigms of knowledge, in particular, the blind spots of science. This reading thereby diverges sharply from those typical of existing literary criticism in that as opposed to being read in terms of and pertaining to the reconstructed context of a past era, the texts are seen as unfolding common concerns in regard to the modernisation of Britain, thus rendering them still relevant today.
Rehkitzrettung und Wildtiersuche mit Drohnen (Multikoptern) - Hintergründe, Verfahrensweisen und Erfahrungen aus der Praxis
Creators: name: Arbes, Stefan
Publisher: name: Zenodo
Year: 2017
Subjects: Drohnen, Rehkitzrettung, Methoden

description: Die Agentur Fin Gadar, eigentlich eine Produktionsagentur mit einem Bereich Luftbildaufnahmen, beschäftigt sich seit etwa 2 Jahren intensiv mit dem Einsatz von drohnengestützten Wärmebildkameras in unterschiedlichen Bereichen. Wir möchten hier nun die Erkenntnisse und Erfahrungen der letzten beiden Jahre zusammenfassen und etwas nötiges Hintergrundwissen vermitteln. Dabei versuchen wir, den sehr umfangreichen Themenkomplex mehr von der konkreten und praktischen Seite zu betrachten, auch wenn hier dadurch das Eine oder Andere stark vereinfacht dargestellt wird.
 Besonderes Augenmerk legen wir dabei vor allem auch auf die praktische Umsetzung und unterschiedliche Verfahrensansätze mit ihren Vor- und Nachteilen. Denn die Anschaffung einer Drohne mit Kamera ist nur ein kleiner Teil der Herausforderung.
 Wir bemühen uns dabei um eine gewisse Objektivität und Unabhängigkeit. Wir verkaufen keine Kopter oder Drohnen. Auf Grund unserer Erfahrungen stellen wir jedoch Ansätze und Ideen zusammen, die wir hoffen, auch mit anderen teilen und auch eventuell Entwicklungspartnerschaften eingehen zu können.
 Aber, um es vorauszuschicken: Richtig eingesetzt, ist die Drohnensuche mit Wärmebildkamera ein äußerst leistungsfähiges Werkzeug zur Unterstützung bei der Rehkitzrettung.
Heinrich Schiller (1897-1978)
Creators: name: Schiller, H.
Publisher: name: ETH Zurich
Year: 1986
Subjects: HANDSCHRIFTENVERZEICHNISSE + HANDSCHRIFTENKATALOGE
Schiller, Heinrich
TECHNIK UND INGENIEURWESEN
SCHWEIZ (MITTELEUROPA). SCHWEIZERISCHE EIDGENOSSENSCHAFT
MANUSCRIPT LITERATURE BIBLIOGRAPHIES
TECHNOLOGY AND ENGINEERING
SWITZERLAND (CENTRAL EUROPE). SWISS CONFEDERATION
info:eu-repo/classification/ddc/620
Engineering & allied operations

description: Handschriften und Autographen der ETH-Bibliothek, 65
Nanoparticle formation and behavior in turbulent spray flames investigated by DNS
Creators: name: Abdelsamie, Abouelmagd
name: Kruis, Frank Einar
name: Wiggers, Hartmut
name: Thévenin, Dominique
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2020
Subjects: subject: Direct numerical simulation
subject: Spray flame
subject: Nanoparticle PSD
subject: 660

description: This work is a first direct numerical simulation of a configuration closely related to the SpraySyn burner (Schneider et al. in Rev Sci Instrum 90:085108, 2019). This burner has been recently developed at the University of Duisburg-Essen to investigate experimentally nanoparticle synthesis in spray flames for a variety of materials. The present simulations are performed for ethanol and titanium tetraisopropoxide as a solvent and precursor, respectively, in order to produce titanium dioxide nanoparticles. In the direct numerical simulations, the complete scenario leading to the production of well-defined nanoparticles is taken into account, including evaporation of the liquid mixture (solvent and precursor) injected as a spray, multi-step kinetics for gas-phase combustion, and finally nanoparticle synthesis. The employed models are described in this article. Additionally, the impact of the inlet velocity of the pilot flame on the nanoparticle synthesis is investigated. It has been found that increasing this speed delays spray flame ignition, decreases nanoparticle concentration, but leads to a narrower size distribution at early stage.
Impact of Host Telomere Length on HHV-6 Integration
Creators: name: Wight, Darren J.
name: Aimola, Giulia
name: Beythien, Georg
name: Flamand, Louis
name: Kaufer, Benedikt B.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: human herpesvirus 6
subject: HHV-6
subject: telomeres
subject: integration
subject: telomere length
subject: TZAP
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten

description: Human herpesvirus 6A and 6B are two closely related viruses that infect almost all humans. In contrast to most herpesviruses, HHV-6A/B can integrate their genomes into the telomeres during the infection process. Both viruses can also integrate in germ cells and subsequently be inherited in children. How HHV-6A/B integrate into host telomeres and the consequences of this remain a subject of active research. Here, we developed a method to measure telomere length by quantitative fluorescence in situ hybridization, confocal microscopy, and computational processing. This method was validated using a panel of HeLa cells having short or long telomeres. These cell lines were infected with HHV-6A, revealing that the virus could efficiently integrate into telomeres independent of their length. Furthermore, we assessed the telomere lengths after HHV-6A integration and found that the virus-containing telomeres display a variety of lengths, suggesting that either telomere length is restored after integration or telomeres are not shortened by integration. Our results highlight new aspects of HHV-6A/B biology and the role of telomere length on virus integration.
title: Ανάπτυξη ενός βασισμένου στην τεχνολογία των πολλαπλών πρακτόρων συστήματος για την προσομοίωση της γραμμής παραγωγής τυπογραφείου
Creators: name: Τσουκάκης Δημήτριος
Publisher: name: Technical University of Crete
Year: 2005

description: Μη διαθέσιμο
Wilhelm Neuweiler (1852-1925)
Creators: name: Neuweiler, Wilhelm
Publisher: name: ETH Zurich
Year: 1986
Subjects: subject: HANDSCHRIFTENVERZEICHNISSE + HANDSCHRIFTENKATALOGE
subject: Neuweiler, Wilhelm
subject: MANUSCRIPT LITERATURE BIBLIOGRAPHIES
subject: info:eu-repo/classification/ddc/510
subject: Mathematics
subject: FOS: Mathematics

description: Handschriften und Autographen der ETH-Bibliothek, 60
On the Properties of Inverse Compton Spectra Generated by Upscattering a Power-law Distribution of Target Photons
Creators: name: Khangulyan, Dmitry
name: Aharonian, Felix
name: Taylor, Andrew M.
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2023
Subjects: subject: 520

description: Relativistic electrons are an essential component in many astrophysical sources, and their radiation may dominate the high-energy bands. Inverse Compton (IC) emission is the radiation mechanism that plays the most important role in these bands. The basic properties of IC, such as the total and differential cross sections, have long been studied; the properties of the IC emission depend strongly not only on the emitting electron distribution but also on the properties of the target photons. This complicates the phenomenological studies of sources, where target photons are supplied from a broad radiation component. We study the spectral properties of IC emission generated by a power-law distribution of electrons on a power-law distribution of target photons. We approximate the resulting spectrum by a broken-power-law distribution and show that there can be up to three physically motivated spectral breaks. If the target photon spectrum extends to sufficiently low energies, (m$_{e}$ and c are electron mass and speed of light, respectively; and are the minimum/maximum energies of target photons and electrons, respectively), then the high-energy part of the IC component has a spectral slope typical for the Thomson regime with an abrupt cutoff close to . The spectra typical for the Klein–Nishina regime are formed above . If the spectrum of target photons features a cooling break, i.e., a change of the photon index by 0.5 at ε$_{br}$, then the transition to the Klein–Nishina regime proceeds through an intermediate change of the photon index by 0.5 at .
title: Βελτιστοποίηση δρομολόγησης οχημάτων διανομής των κατεψυγμένων προϊόντων της παγκύπριας εταιρίας αρτοποιών
Creators: name: Ανδρέου Χαράλαμπος
Publisher: name: Technical University of Crete
Year: 2005

description: Μη διαθέσιμο
Supplementary document for High-efficiency plasmonic vortex generation with near-infrared bifunctional metasurfaces - 6610173.pdf
Creators: name: Chen, Yizhen
name: Zheng, Xiaoying
name: Liu, Feifei
name: Pan, Weikang
name: Wang, Zhuo
name: Liu, Muhan
name: Zhu, Zhiyan
name: Wang, Yingying
name: Li, Liangwei
name: He, Qiong
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: Supplementary Document
Cardiovascular magnetic resonance feature tracking in pigs: a reproducibility and sample size calculation study
Creators: name: Faragli, Alessandro
name: Tanacli, R.
name: Kolp, C.
name: Lapinskas, T.
name: Stehning, C.
name: Schnackenburg, B.
name: Lo Muzio, F. P.
name: Perna, S.
name: Pieske, Burkert
name: Nagel, E.
name: Post, Heiner
name: Kelle, Sebastian
name: Alogna, Alessio
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Cardiovascular magnetic resonance
subject: Feature tracking
subject: Left ventricular strain
subject: Reproducibility
subject: Sample size
subject: Porcine model
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Cardiovascular magnetic resonance feature tracking (CMR-FT) is a novel technique for non-invasive assessment of myocardial motion and deformation. Although CMR-FT is standardized in humans, literature on comparative analysis from animal models is scarce. In this study, we measured the reproducibility of global strain under various inotropic states and the sample size needed to test its relative changes in pigs. Ten anesthetized healthy Landrace pigs were investigated. After baseline (BL), two further steps were performed: (I) dobutamine-induced hyper-contractility (Dob) and (II) verapamil-induced hypocontractility (Ver). Global longitudinal (GLS), circumferential (GCS) and radial strain (GRS) were assessed. This study shows a good to excellent inter- and intra-observer reproducibility of CMR-FT in pigs under various inotropic states. The highest inter-observer reproducibility was observed for GLS at both BL (ICC 0.88) and Ver (ICC 0.79). According to the sample size calculation for GLS, a small number of animals could be used for future trials.
Additional file 1 of Potential of high dimensional radiomic features to assess blood components in intraaortic vessels in non-contrast CT scans
Creators: name: Mahmoudi, Scherwin
name: Martin, Simon S.
name: Ackermann, Jörg
name: Zhdanovich, Yauheniya
name: Koch, Ina
name: Vogl, Thomas J.
name: Albrecht, Moritz H.
name: Lenga, Lukas
name: Bernatz, Simon
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: Hematology

description: Additional file 1. Calculation of the radiomics quality score for this study ( https://radiomics.world/rqs ) [38].
Paul Spiess (1882-1959): Korrespondenz
Creators: name: Spiess, Paul
Publisher: name: ETH Zurich
Year: 1986
Subjects: HANDSCHRIFTENVERZEICHNISSE + HANDSCHRIFTENKATALOGE
Spiess, Paul
MANUSCRIPT LITERATURE BIBLIOGRAPHIES
info:eu-repo/classification/ddc/620
Engineering & allied operations

description: Handschriften und Autographen der ETH-Bibliothek, 62