cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Eukaryotic Cell Permeabilisation to Identify New Putative Chlamydial Type III Secretion System Effectors Secreted within Host Cell Cytoplasm
Creators: name: Kebbi-Beghdadi, Carole
name: Pilloux, Ludovic
name: Martin, Virginie
name: Greub, Gilbert
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Chlamydia trachomatis
Waddlia chondrophila
Type III Secretion System
effectors
perfringolysin O
selective permeabilisation
host-pathogen interactions
virulence factors
nuclear effector

description: Chlamydia trachomatis and Waddlia chondrophila are strict intracellular bacteria belonging to the Chlamydiales order. C. trachomatis is the most frequent bacterial cause of genital and ocular infections whereas W. chondrophila is an opportunistic pathogen associated with adverse pregnancy outcomes and respiratory infections. Being strictly intracellular, these bacteria are engaged in a complex interplay with their hosts to modulate their environment and create optimal conditions for completing their life cycle. For this purpose, they possess several secretion pathways and, in particular, a Type III Secretion System (T3SS) devoted to the delivery of effector proteins in the host cell cytosol. Identifying these effectors is a crucial step in understanding the molecular basis of bacterial pathogenesis. Following incubation of infected cells with perfringolysin O, a pore-forming toxin that binds cholesterol present in plasma membranes, we analysed by mass spectrometry the protein content of the host cell cytoplasm. We identified 13 putative effectors secreted by C. trachomatis and 19 secreted by W. chondrophila. Using Y. enterocolitica as a heterologous expression and secretion system, we confirmed that four of these identified proteins are secreted by the T3SS. Two W. chondrophila T3SS effectors (hypothetical proteins Wcw_0499 and Wcw_1706) were further characterised and demonstrated to be early/mid-cycle effectors. In addition, Wcw_1706 is associated with a tetratricopeptide domain-containing protein homologous to C. trachomatis class II chaperone. Furthermore, we identified a novel C. trachomatis effector, CT460 that localises in the eukaryotic nucleus when ectopically expressed in 293 T cells.
Pre-Recorded Telephone Messages As An Alternative To Follow-Up Survey Reminder Postcards II: The Effectiveness Of Automated Telephone Reminder Messages Used During The 2007 Pennsylvania County Estimates Survey
Creators: name: McCarthy, Jaki S.
name: McCarthy, Jaki S.
Publisher: name: Unknown
Year: 2008
Subjects: subject: Research and Development/Tech Change/Emerging Technologies
subject: autodialer
subject: automated message
subject: follow-up reminder
subject: postcard reminder
subject: response rate

description: Software which dials specified telephone numbers and delivers an automated telephone message was tested as an alternative to postcard reminders in the Pennsylvania County Estimates Survey. Similar to prior research (McCarthy, 2007), software automatically dialed and delivered a pre-recorded message to two randomly selected subsamples of operations. In the present experiment, one subsample received a message recorded by an unidentified speaker (the field office director) following the first mailing of the questionnaire. A second subsample received the same message recorded by the Pennsylvania Secretary of Agriculture. A third random sample received the same reminder message from the field office director, on a traditional postcard reminder delivered via US Postal Service mail. Response rates for each of these groups were compared to a control group which received no reminder. All three reminder groups had higher response rates than the control group, but unlike a previous test, the highest response rate was produced by the generic automated telephone message.
Intrinsic noise of a micro-mechanical displacement detector based on the radio-frequency single-electron transistor
Creators: name: Zhang, Yong
name: Blencowe, Miles
Publisher: name: arXiv
Year: 2001
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the intrinsic noise of a micro-mechanical displacement detector based on the radio-frequency single-electron transistor (rf-SET). Using the noise analysis of a SET by Korotkov as our starting point, we determine the spectral density of the displacement noise due to the tunneling current shot noise. The resulting mechanical displacement noise decreases in inverse proportion to the increasing gate voltage. In contrast, the displacement noise due to the fluctuating SET island charge increases approximately linearly with increasing gate voltage. Taking into account both of these noise sources results in an optimum gate voltage value for the lowest displacement noise and hence best sensitivity. We show that a displacement sensitivity of about 10^-4 Angstroms and a force sensitivity of about 10^-16 N are predicted for a micron-sized cantilever with a realizable resonant frequency 100 MHz and quality factor Q~10^4. Such sensitivities would allow the detection of quantum squeezing in the mechanical motion of the micro-mechanical cantilever and the detection of single-spin magnetic resonance in magnetic resonance force microscopy (MRFM).
description: 24 pages, 7 figures
Aenictophila Seevers 1965
Creators: name: Hlaváč, Peter
name: Newton, Alfred F.
name: Maruyama, Munetoshi
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Aenictophila

description: Aenictophila Seevers
 Aenictophila Seevers, 1965: 285. Type species: Aenictophila thailandica Seevers, 1965, by original designation thailandica Seevers, 1965: 286 (Aenictophila, TL: Pak Chong (80-90 miles north of Bangkok), Thailand; HA:
 Aenictus binghami) Distribution: Thailand
description: Published as part of Hlaváč, Peter, Newton, Alfred F. & Maruyama, Munetoshi, 2011, World catalogue of the species of the tribe Lomechusini (Staphylinidae: Aleocharinae) 3075, pp. 1-151 in Zootaxa 3075 on page 18
Flavin-Conjugated Iron Oxide Nanoparticles as Enzyme-Inspired Photocatalysts for Azo Dye Degradation
Creators: name: Nehme, Samer I.
name: Crocker, Leander
name: Fruk, Ljiljana
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: water remediation
photoreduction
photooxidation
azo dye
flavin
iron oxide nanoparticles
charge transfer
reactive oxygen species
electron donor

description: In this work, a new photocatalytic system consisting of iron oxide nanoparticles (IONPs), coated with a catechol-flavin conjugate (DAFL), is synthesized and explored for use in water remediation. In order to test the efficiency of the catalyst, the photodegradation of amaranth (AMT), an azo dye water pollutant, was performed under aerobic and anaerobic conditions, using either ethylenediaminetetraacetic acid (EDTA) or 2-(N-morpholino)ethanesulfonic acid (MES) as electron donors. Depending on the conditions, either dye photoreduction or photooxidation were observed, indicating that flavin-coated iron-oxide nanoparticles can be used as a versatile enzyme-inspired photocatalysts.
Fast 3D Extended Target Tracking using NURBS Surfaces
Creators: name: Naujoks, Benjamin
name: Burger, Patrick
name: Wuensche, Hans-Joachim
Publisher: name: arXiv
Year: 2019
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This paper proposes fast and novel methods to jointly estimate the target's unknown 3D shape and dynamics. Measurements are noisy and sparsely distributed 3D points from a light detection and ranging (LiDAR) sensor. The methods utilize non-uniform rational B-splines (NURBS) surfaces to approximate the target's shape. One method estimates Cartesian scaling parameters of a NURBS surface, whereas the second method estimates the corresponding NURBS weights, too. Major advantages are the capability of estimating a fully 3D shape as well as the fast processing time. Real-world evaluations with a static and dynamic vehicle show promising results compared to state-of-the-art 3D extended target tracking algorithms.
description: In Proceedings of IEEE Intelligent Transportation Systems Conference (ITSC), 2019
Quantifying the Effects of Weak Stellar Flybys on the Solar System
Creators: name: Brown, Garett
name: Rein, Hanno
Publisher: name: Zenodo
Year: 2021
Subjects: Dynamics

description: The architecture and evolution of planetary systems are shaped in part by stellar flybys. The strength and frequency of stellar flybys vary over system lifetimes as local stellar environments mature. Within this context, we look at flyby encounters which are too weak to immediately destabilize a planetary system but are nevertheless strong enough to measurably perturb a system’s dynamical state. We estimate the strength of such perturbations on a secularly evolving system using a simple analytic model and confirm those estimates with direct N-body simulations. We then run long-term integrations of our own Solar System and show that even small perturbations from stellar flybys can significantly affect the stability of planetary systems over their lifetime. Due to the coupled nature of the Solar System, we find that small perturbations to Neptune’s orbit cascade inward, increasing the likelihood that the inner Solar System will destabilize. We find that interactions which change the semi-major axis of Neptune by >0.03 AU are significantly more likely to destabilize the Solar System.
description: {"references": ["Bailer-Jones, C. A. L., Rybizki, J., Andrae, R., & Fouesneau, M. 2018, A&A, 616, A37", "Batygin, K., Morbidelli, A., & Holman, M. J. 2015, ApJ, 799, 120", "Laskar, J. 2000, Physical Review Letters, 84, 3240", "Laskar, J. & Gastineau, M. 2009, Nat, 459, 817", "Lithwick, Y. & Wu, Y. 2011, ApJ, 739, 31", "Spurzem, R., Giersz, M., Heggie, D. C., & Lin, D. N. 2009, ApJ, 697, 458", "Rein, H., Brown, G., & Tamayo, D. 2019, MNRAS, stz2942", "Rein, H., Tamayo, D., & Brown, G. 2019, MNRAS, 489, 4632", "Zakamska, N. L. & Tremaine, S. 2004, AJ, 128, 869", "Zink, J. K., Batygin, K., & Adams, F. C. 2020, AJ, 160, 232"]}
Additional file 2 of Association of mental health status between self-poisoning suicide patients and their family members: a matched-pair analysis
Creators: name: Zheng, Wenjing
name: Han, Limei
name: Fan, Yanna
name: Yi, Min
name: Lu, Xiaoxia
name: Yang, Juan
name: Peng, Xiaobo
name: Yang, Ying
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Hematology

description: Additional file 2: Supplementary table 2. Multivariable analysis of significant characteristics for predicting self-poisoning suicide among patients after adjusting for age and gender (n=151).
Categorizing Nonresponse Occurring in the 2007 June Area Survey (California, Kansas, New York, Virginia, and Washington)
Creators: name: Gerling, Michael W.
name: Tran, HoaiNam N.
name: Earp, Morgan S.
name: O'Connor, Terry P.
name: Gerling, Michael W.
name: Tran, HoaiNam N.
name: Earp, Morgan S.
name: O'Connor, Terry P.
Publisher: name: Unknown
Year: 2008
Subjects: subject: Land Economics/Use
subject: Research Methods/ Statistical Methods
subject: Agriculture
subject: Refusals
subject: Inaccessibles
subject: Data Collection
subject: Nonresponse

description: The National Agricultural Statistics Service (NASS) surveys farmers and ranchers across the United States and Puerto Rico in order to estimate crops and livestock, assess production practices, and identify economic trends. One of the surveys conducted annually is the June Area Survey (JAS). This survey requires field enumerators to visit sampled land areas (segments) designated on aerial photos and record all agricultural activity occurring within those specified land areas. Over the past eight years, the national JAS’s overall response rate has been gradually deteriorating from 86.5 percent in 2000 to 81.7 percent in 2007. Assuming this trend continues, the JAS national response rate will fall below the Office of Management and Budget’s threshold rate of 80 percent in three to four years. Falling below this rate dictates the need for nonresponse bias analysis and, in general, heightens the concern about the potential negative impact of nonresponse on survey results. This study examines some of the underlying causes of nonresponse in the 2007 June Area Survey in five states (California, Kansas, New York, Virginia, and Washington).
Measurement of Superluminal optical tunneling times in double-barrier photonic bandgaps
Creators: name: Longhi, S.
name: Laporta, P.
name: Belmone, M.
name: Recami, E.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Optics (physics.optics)
subject: Classical Physics (physics.class-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Tunneling of optical pulses at 1.5 micron wavelength through double-barrier periodic fiber Bragg gratings is experimentally investigated. Tunneling time measurements as a function of barrier distance show that, far from the resonances of the structure, the transit time is paradoxically short, implying Superluminal propagation, and almost independent of the distance between the barriers. These results are in agreement with theoretical predictions based on phase time analysis and also provide an experimental evidence, in the optical context, of the analogous phenomenon expected in Quantum Mechanics for non-resonant superluminal tunneling of particles across two successive potential barriers. [Attention is called, in particular, to our last Figure]. PACS nos.: 42.50.Wm, 03.65.Xp, 42.70.Qs, 03.50.De, 03.65.-w, 73.40.Gk
description: LaTeX file (8 pages), plus 5 figures
Additional file 3 of Association of mental health status between self-poisoning suicide patients and their family members: a matched-pair analysis
Creators: name: Zheng, Wenjing
name: Han, Limei
name: Fan, Yanna
name: Yi, Min
name: Lu, Xiaoxia
name: Yang, Juan
name: Peng, Xiaobo
name: Yang, Ying
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Hematology

description: Additional file 3: Supplementary table 3. Multivariable analysis of significant characteristics in terms of matched family members for predicting self-poisoning suicide among patients after adjusting for age and gender (n=151).
Phylogenetic Analysis and Karyotype Evolution in Two Species of Core Gruiformes: Aramides cajaneus and Psophia viridis
Creators: name: Furo, Ivanete De Oliveira
name: Kretschmer, Rafael
name: O’Brien, Patrícia C. M.
name: Pereira, Jorge C.
name: Ferguson-Smith, Malcolm A.
name: De Oliveira, Edivaldo Herculano Corrêa
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Rallidae
Psophiidae
cytogenetic
chromosome evolution
phylogenetic

description: Gruiformes is a group with phylogenetic issues. Recent studies based on mitochondrial and genomic DNA have proposed the existence of a core Gruiformes, consisting of five families: Heliornithidae, Aramidae, Gruidae, Psophiidae and Rallidae. Karyotype studies on these species are still scarce, either by conventional staining or molecular cytogenetics. Due to this, this study aimed to analyze the karyotype of two species (Aramides cajaneus and Psophia viridis) belonging to families Rallidae and Psopiidae, respectively, by comparative chromosome painting. The results show that some chromosome rearrangements in this group have different origins, such as the association of GGA5/GGA7 in A. cajaneus, as well as the fission of GGA4p and association GGA6/GGA7, which place P. viridis close to Fulica atra and Gallinula chloropus. In addition, we conclude that the common ancestor of the core Gruiformes maintained the original syntenic groups found in the putative avian ancestral karyotype.
Modeling Non-response in National Agricultural Statistics Service (NASS) Surveys Using Classification Trees
Creators: name: McCarthy, Jaki S.
name: Jacob, Thomas
name: McCraken, Amanda
name: McCarthy, Jaki S.
name: Jacob, Thomas
name: McCraken, Amanda
Publisher: name: Unknown
Year: 2010
Subjects: subject: Research Methods/ Statistical Methods
subject: Non-response Models
subject: Classification Trees
subject: Refusal
subject: Non-contact

description: This paper describes the use of classification trees to predict survey refusals and inaccessibles. Data from auxiliary sources were matched to the 2006 and 2007 March, September, and December Crops/Stocks survey sample members. The data matched included variables such as establishment size (both in dollars and acres), type of commodities produced, operating arrangement, operator characteristics (such as race, age, gender, etc.) from the Census of Agriculture, paradata describing their NASS reporting history (past NASS survey response, refusals, etc.), Joint Burden Indicators, and characteristics of the location of the operation (by county and zip code) that were available from the Census Bureau. Classification trees used these data to repeatedly divide our dataset to identify subsets of records more likely to be survey non-respondents. This approach was initially applied to the NASS Crops/Stocks survey, and then applied to other NASS surveys. The results from our models indicate the relatively small subset of variables that are important in predicting survey response. The most useful variables all come from the set of NASS reporting history variables. These models work consistently for the Crops/Stocks survey and for some surveys such as Cattle, but less well for others such as ARMS. Using these models, sampled operations can be ranked based on their predicted response likelihood. These may be useful for field offices to plan alternative data collection strategies for the operations most likely to be non-respondents.
A comparison of the R_h=ct and LCDM cosmologies based on the observed halo mass function
Creators: name: Yennapureddy, Manoj K.
name: Melia, Fulvio
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The growth of structure probes the re-ionization history and quasar abundance in the Universe, constituting an important probe of the cosmological predictions. Halos are not directly observable, however, so their mass and evolution must be inferred indirectly. Studies based on the assumption of a constant halo to stellar mass ratio M_h/M_* (extrapolated from z<4) reveal significant tension with LCDM---a failure known as "The Impossibly Early Galaxy Problem". But whether this ratio evolves or remains constant through redshift 4
description: 10 pages, 7 figures. Accepted for publication in EPJ-C
Gauge unification in 5-D SU(5) model with orbifold breaking of GUT symmetry
Creators: name: Brahmachari, Biswajoy
name: Raychaudhuri, Amitava
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider a 5-dimensional SU(5) model wherein the symmetry is broken to the 4-dimensional Standard Model by compactification of the 5th dimension on an S^1/(Z_2 \times Z^\prime_2) orbifold. We identify the members of all SU(5) representations upto 75 which have zero modes. We examine how these light scalars affect gauge coupling unification assuming a single intermediate scale and present several acceptable solutions. The 5-D compactification scale coincides with the unification scale of gauge couplings and is determined via this renormalization group analysis. When SO(10) is considered as the GUT group there are only two solutions, so long as a few low dimensional scalar multiplets upto 126 are included.
description: Latex, 1 eps figure
Protein driven lipid domain nucleation in biological membranes
Creators: name: Hoferer, Moritz
name: Bonfanti, Silvia
name: Taloni, Alessandro
name: La Porta, Caterina A. M.
name: Zapperi, Stefano
Publisher: name: arXiv
Year: 2019
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Lipid rafts are heterogeneous dynamic lipid domains of the cell membranes that are involved in several biological processes, like protein and lipids specific transport and signaling. Our understanding of lipid raft formation is still limited, due to the transient and elusive nature of these domains {\it in vivo}, in contrast to the stable phase-separated domains observed in artificial membranes. Inspired by experimental findings highlighting the relevance of transmembrane proteins for lipid rafts, we investigate lipid domain nucleation by coarse-grained molecular dynamics and Ising model simulations. We find that the presence of a transmembrane protein can trigger lipid domain nucleation in a flat membrane from an otherwise mixed lipid phase. Furthermore, we study the role of the lipid domain in the diffusion of the protein showing that its mobility is hindered by the presence of the raft. The results of our coarse-grained molecular dynamics and Ising model simulations thus coherently support the important role played by transmembrane proteins in lipid domain formation and stability.
description: 9 pages, 7 figures, revision of typos und punctuation, replacement of media links to freely accessible platforms
DOVER: A Method for Combining Diarization Outputs
Creators: name: Stolcke, Andreas
name: Yoshioka, Takuya
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Speech recognition and other natural language tasks have long benefited from voting-based algorithms as a method to aggregate outputs from several systems to achieve a higher accuracy than any of the individual systems. Diarization, the task of segmenting an audio stream into speaker-homogeneous and co-indexed regions, has so far not seen the benefit of this strategy because the structure of the task does not lend itself to a simple voting approach. This paper presents DOVER (diarization output voting error reduction), an algorithm for weighted voting among diarization hypotheses, in the spirit of the ROVER algorithm for combining speech recognition hypotheses. We evaluate the algorithm for diarization of meeting recordings with multiple microphones, and find that it consistently reduces diarization error rate over the average of results from individual channels, and often improves on the single best channel chosen by an oracle.
description: Minor corrections to results in Table 2, row 1. Code made available at http://github.com/stolcke/dover
title: Improving Augmentative and Alternative Communication Use Between Mothers, Siblings, and Children with Communication Disabilities
Creators: name: Gatt, Marica
Publisher: name: University of Kent
Year: 2022

description: Siblings are essential communication partners within the family support system with longest-lasting relationships within a family structure (Howe et al., 2015). However, there is limited research about the inter-relationships between mothers, siblings and children with intellectual and developmental disabilities (IDD) who benefit from augmentative and alternative communication (AAC). This thesis explores the communicative interactions between mothers, siblings and children with IDD who use AAC to support their comprehensive and expression of spoken language (Ganz et al., 2014). Thus, a systematic review of the literature of family-led interventions was conducted. A total of 21 studies, including 6 groups studies and 15 single-case experimental designs, were included in the coding and analysis stage. A range of interventions, including parent and sibling training programmes storybooks and speech generated devices, were reported. The need for more research in mother-sibling-focal child interactions where a child has a communication disability was highlighted. Therefore, the first study consisted of a Pilot study involving three families of children with communication disabilities. Two independent small-scale studies involved six families of typically developing children (study 2a) and six families of children with communication disabilities (study 2b). The researcher aimed to understand behaviour patterns in mother-sibling-focal child interactions for typically and atypically developing children. A mixed-methods study design involving both qualitative and quantitative methods wsa used. Mothers and siblings presented with a range of behaviours that were in synchrony with the mothers' and children's responsivity and their emotional capacity to respond to each other. Despite the benefits of using AAC in the home, it was evident that no consistent and functional use was observed. In view of this, a final study was conducted to evaluate the effects of sibling-mediated interventions using existing modes of communication within the home environment. A pre/post-test research design of three phases was chosen: baseline, instructional, and post-instructional. Observational data were collected on reciprocal sibling-focal child interactions, use of prompts directed towards the sibling of focal child, and levels of proximity. Results suggested an increase in sibling-focal child initiations and responses while parental prompts decreased following the intervention. These results confirm that siblings may be excellent co-interventionists in the intervention process, and wit hthe right level of support, the use of a communication system may be successfully implemented within the home environmental. Finally, implications and recommendations for further research were discussed for improving the social interactions of siblings and the focal child within the home environment.
Mathematical Foundations of the Relativistic Theory of Quantum Gravity
Creators: name: De Aquino, Fran
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: Starting from the action function, we have derived a theoretical background that leads to the quantization of gravity and the deduction of a correlation between the gravitational and the inertial masses, which depends on the kinetic momentum of the particle. We show that the strong equivalence principle is reaffirmed and, consequently, Einstein's equations are preserved. In fact, such equations are deduced here directly from this new approach to Gravitation. Moreover, we have obtained a generalized equation for the inertial forces, which incorporates the Mach's principle into Gravitation. Also, we have deduced the equation of Entropy; the Hamiltonian for a particle in an electromagnetic field and the reciprocal fine structure constant directly from this new approach. It was also possible to deduce the expression of the Casimir force and to explain the Inflation Period and the Missing Matter, without assuming existence of vacuum fluctuations. This new approach to Gravitation will allow us to understand some crucial matters in Cosmology.
description: 76 pages, PDF. arXiv admin note: substantial text overlap with arXiv:gr-qc/9910036
Aenictozyras Kistner & Jacobson 1975
Creators: name: Hlaváč, Peter
name: Newton, Alfred F.
name: Maruyama, Munetoshi
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Aenictozyras

description: Aenictozyras Kistner & Jacobson
 Aenictozyras Kistner & Jacobson, 1975: 39. Type species: Aenictozyras flavus Kistner & Jacobson, by original designation flavus Kistner & Jacobson, 1975: 41 (Aenictozyras, TL: Philippines, Negros Island, Damaguete; HA: Aenictus gracilis) Distribution: Philippines
description: Published as part of Hlaváč, Peter, Newton, Alfred F. & Maruyama, Munetoshi, 2011, World catalogue of the species of the tribe Lomechusini (Staphylinidae: Aleocharinae) 3075, pp. 1-151 in Zootaxa 3075 on page 18
Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models
Creators: name: Dunlop, Charles R.
name: Wallez, Yann
name: Johnson, Timothy Isaac
name: Bernaldo De Quirós Fernández, Sandra
name: Durant, Stephen T.
name: Cadogan, Elaine B.
name: Lau, Alan
name: Richards, Frances M.
name: Jodrell, Duncan I.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/80/86/2371
/631/67/1059/602
/631/67/1059/99
/631/67/1504/1713
/631/154/53/2423
article

description: Abstract: Background: Personalised medicine strategies may improve outcomes in pancreatic ductal adenocarcinoma (PDAC), but validation of predictive biomarkers is required. Having developed a clinical trial to assess the ATR inhibitor, AZD6738, in combination with gemcitabine (ATRi/gem), we investigated ATM loss as a predictive biomarker of response to ATRi/gem in PDAC. Methods: Through kinase inhibition, siRNA depletion and CRISPR knockout of ATM, we assessed how ATM targeting affected the sensitivity of PDAC cells to ATRi/gem. Using flow cytometry, immunofluorescence and immunoblotting, we investigated how ATRi/gem synergise in ATM-proficient and ATM-deficient cells, before assessing the impact of ATM loss on ATRi/gem sensitivity in vivo. Results: Complete loss of ATM function (through pharmacological inhibition or CRISPR knockout), but not siRNA depletion, sensitised to ATRi/gem. In ATM-deficient cells, ATRi/gem-induced replication catastrophe was augmented, while phospho-Chk2-T68 and phospho-KAP1-S824 persisted via DNA-PK activity. ATRi/gem caused growth delay in ATM-WT xenografts in NSG mice and induced regression in ATM-KO xenografts. Conclusions: ATM loss augments replication catastrophe-mediated cell death induced by ATRi/gem and may predict clinical responsiveness to this combination. ATM status should be carefully assessed in tumours from patients with PDAC, since distinction between ATM-low and ATM-null could be critical in maximising the success of clinical trials using ATM expression as a predictive biomarker.
Moment-operator expansion for the two-meson, two-photon and fermion-antifermion states
Creators: name: Anisovich, A. V.
name: Anisovich, V. V.
name: Markov, V. N.
name: Matveev, M. A.
name: Sarantsev, A. V.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A complete set of formulae in terms of the moment-operator expansion is presented for the two-meson, two-photon and fermion-antifermion states that can be used in the analysis of scalar (S) and pseudoscalar (P) meson production in anti-p p and gamma-gamma collisions: anti-p p -> SS, PP, SP and gamma gamma -> SS, PP, SP.
description: 21 pages, Latex, no fugures
title: How does living in a rural location affect experiences of acquired vision impairment?
Creators: name: Woods, Rebecca Ayrton
Publisher: name: University of Plymouth
Year: 2024
Subjects: subject: rurality, vision impairment, blindness, rehabilitation, sensory research, IPA, inclusion, happiness
subject: Other (e.g., MD, EdD, DBA, DClinPsy)

description: This research explores the lived experiences of adults with acquired sight loss who live in rural areas in Southwest England. There is a scarcity of published academic research with this group. Vision impaired people who live in rural locations are therefore unrecognised sources of vision impairment rehabilitation knowledge. The research is conducted in an interpretivist paradigm. The research is guided by phenomenological understanding, rooted in Merleau-Ponty’s concepts of perception, the centrality of tool-use, and human embodiment. Attention is centred on the process of adapting to sight loss in a domestic setting, placing this research in an experiential, community-based educational context. The researcher openly acknowledges her professional migration from urban to rural areas has informed this study. The interview method is an adaptation of the visual imagery-based Z-MET interview technique, re-designed for this group of participants. This study is connected to other multi-sensory research, particularly sensory ethnography. Semi-structured interviews were conducted with eight vision impaired people living in rural Southwest England, generating descriptive data. Interviews were analysed using an Interpretative Phenomenological Analysis framework. The identified themes, Light and Sound; Blindness: a state of difference; Changes in A Working Life; Me, My People and My Animals; My Rural Home; I am what I eat; each express an aspect of participants’ daily lives that is significant. The themes demonstrate how fundamental rurality is for every participant irrespective of whether this was chosen or the outcome of happenstance. This research shows how rural life remains emphatically different from urban living. This research identifies and conveys participants’ living expertise. In conclusion, implications for both vision impairment rehabilitation service policies and professional practice are stated.
Critical Infrastructure Protection in the Water Sector: A 2030 Outlook
Creators: name: Dimou, Anastasios
name: Peroulis, Konstantinos
Publisher: name: Zenodo
Year: 2025

description: EU-CIP has released a white paper on protecting critical drinking water infrastructure, highlighting threats like aging systems, cyber risks, and climate events, while proposing guidelines and R&I roadmaps to boost resilience.
The multispectral image after threshold
Creators: name: Zhang, Jun
Publisher: name: figshare
Year: 2019
Subjects: subject: 70303 Crop and Pasture Biochemistry and Physiology
subject: FOS: Agriculture, forestry and fisheries
subject: 70105 Agricultural Systems Analysis and Modelling
subject: FOS: Other agricultural sciences

description: this is the raw multipectral image after threshold
Constraints on the Variations of the Fundamental Couplings
Creators: name: Olive, Keith A.
name: Pospelov, Maxim
name: Qian, Yong-Zhong
name: Coc, Alain
name: Casse, Michel
name: Vangioni-Flam, Elisabeth
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We reconsider several current bounds on the variation of the fine-structure constant in models where all gauge and Yukawa couplings vary in an interdependent manner, as would be expected in unified theories. In particular, we re-examine the bounds established by the Oklo reactor from the resonant neutron capture cross-section of 149Sm. By imposing variations in Λ_{QCD} and the quark masses, as dictated by unified theories, the corresponding bound on the variation of the fine-structure constant can be improved by about 2 orders of magnitude in such theories. In addition, we consider possible bounds on variations due to their effect on long lived α- and β-decay isotopes, particularly 147Sm and 187Re. We obtain a strong constraint on Δα/ α, comparable to that of Oklo but extending to a higher redshift corresponding to the age of the solar system, from the radioactive life-time of 187Re derived from meteoritic studies. We also analyze the astrophysical consequences of perturbing the decay Q values on bound state β-decays operating in the s-process.
description: 25 pages, latex, 5 eps figures
Demand for Varied Fruit and Vegetable Colors
Creators: name: Steele, Marie
name: Weatherspoon, Dave
name: Steele, Marie
name: Weatherspoon, Dave
Publisher: name: Unknown
Year: 2016
Subjects: subject: Consumer/Household Economics
subject: Demand and Price Analysis
subject: Food Consumption/Nutrition/Food Safety
subject: Health Economics and Policy
subject: fruit and vegetable colors
subject: quaids
subject: low income
subject: Hispanic

description: The objective of this study is to assess the demand for fruit and vegetable (F&V) colors. Consumer preferences for F&V colors have yet to be examined though nutritional health benefits are associated with color and the USDA has promoted consumption based on the F&V color. Supermarket scanner receipt data from an independent supermarket in a primarily Hispanic neighborhood in the Midwest was collected from May 2014 through January 2015 and transformed into a panel dataset of customers’ two-week purchases. F&V were divided into four color classes: green, white, red/blue/purple, and yellow/orange. The Quadratic Almost Ideal Demand System adjusted to account for the large proportions of non-purchases and to control for additional explanatory variables was used for analysis. F&V weak separability was tested and failed; hence, eight color expenditure share equations (four for fruits and four for vegetables) were estimated within one model. Expenditures and prices significantly impact the demand for the F&V colors. Consumers are most price responsive to white F&V and most expenditure responsive to the red/blue/purple and yellow/orange F&V.
Singular Reduction of the 2-Body Problem on the 3-Sphere and the 4-Dimensional Spinning Top
Creators: name: Arathoon, Philip
Publisher: name: arXiv
Year: 2019
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: We consider the dynamics and symplectic reduction of the 2-body problem on a sphere of arbitrary dimension. It suffices to consider the case for when the sphere is 3-dimensional and where we take the group of symmetries to be $SO(4)$. As the 3-sphere is a group, both left and right multiplication on itself are commuting symmetries which together generate the full symmetry group. This gives rise to a notion of left and right momenta for the problem, and allows for a reduction in stages, first by the left and then the right, or vice versa. The intermediate reduced spaces obtained by left or right reduction are shown to be coadjoint orbits of the special Euclidean group $SE(4)$. The full reduced spaces are generically 4-dimensional and we describe these spaces and their singular strata. The dynamics of the 2-body problem descend through a double cover to give a dynamical system on $SO(4)$, which after reduction is the same as that of a 4-dimensional spinning top with symmetry. This connection allows us to `hit two birds with one stone' and derive results about both the spinning top and the 2-body problem simultaneously. We provide the equations of motion on the reduced spaces and fully classify the relative equilibria and discuss their stability.
description: 21 pages
Neurocomputational mechanisms underpinning aberrant social learning in young adults with low self-esteem
Creators: name: Will, Geert-Jan
name: Moutoussis, Michael
name: Womack, Palee M.
name: Bullmore, Edward T.
name: Goodyer, Ian M.
name: Fonagy, Peter
name: Jones, Peter B.
name: Rutledge, Robb B.
name: Dolan, Raymond J.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/378
/631/477
/59/36
article

description: Funder: UCLH NIHR BRC
description: Abstract: Low self-esteem is a risk factor for a range of psychiatric disorders. From a cognitive perspective a negative self-image can be maintained through aberrant learning about self-worth derived from social feedback. We previously showed that neural teaching signals that represent the difference between expected and actual social feedback (i.e., social prediction errors) drive fluctuations in self-worth. Here, we used model-based functional magnetic resonance imaging (fMRI) to characterize learning from social prediction errors in 61 participants drawn from a population-based sample (n = 2402) who were recruited on the basis of being in the bottom or top 10% of self-esteem scores. Participants performed a social evaluation task during fMRI scanning, which entailed predicting whether other people liked them as well as the repeated provision of reported feelings of self-worth. Computational modeling results showed that low self-esteem participants had persistent expectations that others would dislike them, and a reduced propensity to update these expectations in response to social prediction errors. Low self-esteem subjects also displayed an enhanced volatility in reported feelings of self-worth, and this was linked to an increased tendency for social prediction errors to determine momentary self-worth. Canonical correlation analysis revealed that individual differences in self-esteem related to several interconnected psychiatric symptoms organized around a single dimension of interpersonal vulnerability. Such interpersonal vulnerability was associated with an attenuated social value signal in ventromedial prefrontal cortex when making predictions about being liked, and enhanced dorsal prefrontal cortex activity upon receipt of social feedback. We suggest these computational signatures of low self-esteem and their associated neural underpinnings might represent vulnerability for development of psychiatric disorder.
Allardiana Levasseur 1966
Creators: name: Hlaváč, Peter
name: Newton, Alfred F.
name: Maruyama, Munetoshi
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Allardiana

description: Allardiana Levasseur
 Allardiana Levasseur, 1966a: 147 [= Levasseur, 1965b: 569, NOMEN NUDUM]. Type species: Allardiana katangana Levasseur, by original designation katangana Levasseur, 1966a: 149 (Allardiana, TL: région de Kolwezi, Katanga, Zilo) Distribution: Dem. Rep. Congo
description: Published as part of Hlaváč, Peter, Newton, Alfred F. & Maruyama, Munetoshi, 2011, World catalogue of the species of the tribe Lomechusini (Staphylinidae: Aleocharinae) 3075, pp. 1-151 in Zootaxa 3075 on page 18
The role of noncoding RNAs in epithelial cancer
Creators: name: Agostini, Massimiliano
name: Ganini, Carlo
name: Candi, Eleonora
name: Melino, Gerry
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Review Article
/631/337/384/2568
/631/337/384/331
review-article

description: Funder: RCUK | Medical Research Council (MRC); doi: https://doi.org/10.13039/501100000265
description: Funder: Fondazione Luigi Maria Monti IDI-IRCCS (RC)
description: Abstract: Regulatory noncoding RNAs (ncRNAs) are a class of RNAs transcribed by regions of the human genome that do not encode for proteins. The three main members of this class, named microRNA, long noncoding RNA, and circular RNA play a key role in the regulation of gene expression, eventually shaping critical cellular processes. Compelling experimental evidence shows that ncRNAs function either as tumor suppressors or oncogenes by participating in the regulation of one or several cancer hallmarks, including evading cell death, and their expression is frequently deregulated during cancer onset, progression, and dissemination. More recently, preclinical and clinical studies indicate that ncRNAs are potential biomarkers for monitoring cancer progression, relapse, and response to cancer therapy. Here, we will discuss the role of noncoding RNAs in regulating cancer cell death, focusing on those ncRNAs with a potential clinical relevance.
Retail Alcohol Availability and Product Diversity
Creators: name: Ho, Shuay-Tsyr
name: Qu, Mingyang
name: Rickard, Bradley
name: Costanigro, Marco
name: McLaughlin, Edward
name: Ho, Shuay-Tsyr
name: Qu, Mingyang
name: Rickard, Bradley
name: Costanigro, Marco
name: McLaughlin, Edward
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agricultural and Food Policy
subject: Consumer/Household Economics
subject: Entropy Index
subject: Grocery stores
subject: Product diversity
subject: Regulation
subject: Wine

description: The repeal of the Prohibition Act in 1933 introduced many state-specific regulations in alcohol markets. As one example of this, several states currently have laws that restrict specific alcoholic beverages in grocery stores, and some states have recently considered lifting these restrictions. Some opponents of such legislative changes claim that allowing alcohol to be more widely distributed would put smaller liquor stores out of business and eventually lead to a narrower set of product choices available to consumers. Here we use the Nielsen Homescan dataset that describes alcoholic beverage purchasing patterns for approximately 70,000 households between 2004 and 2012 to examine this issue empirically. Our results show that, even when controlling for preferences for variety, consumers in states that allow beer and wine sales in grocery stores have greater diversity in their purchases of beer and wine. Overall, the findings suggest that expanding the retail availability of beer and wine may actually increase the diversity of alcoholic beverage products purchased by consumers in those states.
Additional file 1 of Physical activity measured using wearable activity tracking devices associated with gout flares
Creators: name: Elmagboul, Nada
name: Coburn, Brian W.
name: Foster, Jeffrey
name: Mudano, Amy
name: Melnick, Joshua
name: Bergman, Debra
name: Yang, Shuo
name: Chen, Lang
name: Filby, Cooper
name: Mikuls, Ted R.
name: Curtis, Jeffrey R.
name: Saag, Kenneth
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Table S1. Completeness of Fitbit® Data across Data Types, and after Imputing Wear Time Across Various Intervals. Effect of imputation using 24 h person-days as unit of aggregation.
Long-Range Microwave Mediated Interactions Between Electron Spins
Creators: name: Borjans, F.
name: Croot, X. G.
name: Mi, X.
name: Gullans, M. J.
name: Petta, J. R.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Entangling gates for electron spins in semiconductor quantum dots are generally based on exchange, a short-ranged interaction that requires wavefunction overlap. Coherent spin-photon coupling raises the prospect of using photons as long-distance interconnects for spin qubits. Realizing a key milestone for spin-based quantum information processing, we demonstrate microwave-mediated spin-spin interactions between two electrons that are physically separated by more than 4 mm. Coherent spin-photon coupling is demonstrated for each individual spin using microwave transmission spectroscopy. An enhanced vacuum Rabi splitting is observed when both spins are tuned into resonance with the cavity, indicative of a coherent spin-spin interaction. Our results demonstrate that microwave-frequency photons can be used as a resource to generate long-range two-qubit gates between spatially separated spins.
Optimal strategies in collective Parrondo games
Creators: name: Dinis, Luis
name: Parrondo, Juan M. R.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Portfolio Management (q-fin.PM)
subject: FOS: Physical sciences
subject: FOS: Economics and business

description: We present a modification of the so-called Parrondo's paradox where one is allowed to choose in each turn the game that a large number of individuals play. It turns out that, by choosing the game which gives the highest average earnings at each step, one ends up with systematic loses, whereas a periodic or random sequence of choices yields a steadily increase of the capital. An explanation of this behavior is given by noting that the short-range maximization of the returns is "killing the goose that laid the golden eggs". A continuous model displaying similar features is analyzed using dynamic programming techniques from control theory.
description: 4 pages, 6 figures, revised version in published form