cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Phytochemical screening by LC-MS and LC-PDA of ethanolic extracts from the fruits of Kigelia africana (Lam.) Benth
Creators: name: Costa, Rosaria
name: Albergamo, Ambrogina
name: Pellizzeri, Vito
name: Dugo, Giacomo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Kigelia africana is a tree native to Africa, with a local employment in numerous fields, ranging from traditional medicine to cosmetics and religious rituals. Parts of the plant generally used are stem bark, fruits, roots and leaves. The fruits, which have a singular ‘sausage’ shape, are widely exploited by local folk, in particular for applications/products involving genito-urinary apparatus of both human genders. The scope of this work was to make a consistent chemical investigation on this plant species, in order to clarify and increase the information at present available in literature. To this aim, ethanolic extracts of K. africana fruits were analysed by high-performance liquid chromatography with photodiode array (HPLC-PDA) and electrospray-mass spectrometry (HPLC-ESI-MS) detection, revealing the presence of polyphenols and iridoids. The two detection systems used along with standard co-injection and comparison with previous reports, led to the identification and quantification of six phenolic compounds and three iridoids.
Nonverbal Synchrony in Long-Term Romantic Couples: Testing for Associations with Relationship Length, Rapport, and Love in the Moment
Creators: name: Lin, Susan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Nonverbal synchrony is a component of Tickle-Degnen and Rosenthal’s 1990 model of rapport that is hypothesized to increase over the duration of social relationships. In this model of rapport, the relative importance of nonverbal synchrony to interactants’ perceptions of their own rapport is also hypothesized to increase over the duration of their relationship. We tested these hypotheses in a sample of 154 romantic couples. Specifically, we predicted that nonverbal synchrony in an unstructured interaction would be associated with relationship length as well as with perceptions of rapport and of momentary feelings of love in the interaction. Furthermore, we predicted that relationship length would moderate associations between nonverbal synchrony and the two other dependent variables; that is, we hypothesized that associations would be stronger in couples who had been together longer. Video recordings of romantic couples engaging in a discussion with their partners about how they first met were coded for nonverbal synchrony using the pose estimation software OpenPose and dynamic time warping. Contrary to expectations, we did not find any associations between nonverbal synchrony and relationship length, rapport, or love in the moment in the present study. Our study also highlights challenges and future directions for using AI-driven computer vision software to code nonverbal synchrony.
Identifying and characterizing scalloped hammerhead shark (Sphyrna lewini) nursery grounds  in the Galápagos
Creators: name: White, Camille
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: A key goal of the conservation of endangered species is the identification and protection of critical habitats, for example, those serving as nursery grounds for some juvenile shark species during their early developmental stages. The scalloped hammerhead shark (Sphyrna lewini) is an iconic and ecologically important species, yet our understanding of its nursery grounds remains limited. For example, only three potential nursery grounds in the Galápagos Islands have been previously identified and characterized, therefore, this study aims to locate and describe additional nurseries. To do so, we conducted an exploratory fishing cruise around the archipelago, deploying gill nets and free floating unbarbed hooks in 17 bays. We recorded environmental data for each bay and measurements for every captured juvenile shark. While we frequently caught blacktips (Carcharhinus limbatus), which is consistent with existing literature on their abundance in various bays all across the archipelago, we only caught the elusive juvenile scalloped hammerheads on the last day of our cruise in Cartago Bay, located on the eastern side of Isabela Island. Due to the presence of juveniles caught in June 2022 and February 2023, Cartago Bay should be recognized as a putative nursery ground for the scalloped hammerhead species. Ongoing efforts to identify and characterize additional nursery grounds are essential in implementing protective measures and formulating much needed recovery plans for this globally critically endangered species.
AI IN TARGETED ADVERTISING AND THE PERSPECTIVE OF COLLEGE STUDENTS
Creators: name: Schulz, Sarah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: The study explores artificial intelligence's (AI) impact on targeted advertising, highlighting its benefits and ethical challenges. It aims to understand how AI integration will change advertising strategies, focusing on privacy and ethical considerations. A thorough literature review covers previous research on the topic. Focus group and survey research present information on college-age participants’ perspectives on AI and its implications. The study seeks to uncover how these viewpoints may shape AI's adoption and impact as these individuals transition into the workforce and influence consumer behavior. The study aims to fill a gap in previous research using a mixed methods approach to obtain quantitative and qualitative data. The results of this study are expected to indicate that college students possess a degree of familiarity with AI and are open to interacting with it, with some reservations regarding transparency and ethical issues. 

Keywords: Artificial intelligence, targeted advertising, privacy, ethics
The Rebirth of Agriculture in a Post-Nuclear Fukushima
Creators: name: Travis, Mika
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: In 2011, an infamous tsunami and nuclear disaster devasted parts of Fukushima Prefecture, Japan. As clouds of radiation spread, the prefecture that was once known for its agricultural produce became feared and stigmatized. This thesis explores the effects of the 2011 nuclear disaster's impact on Fukushima's agricultural industry and recent efforts to bring back agriculture to a town nearby the Fukushima Daiichi Nuclear Power Plant. This research culminated in a multimedia journalism project.
23-50-1-SM.pdf
Creators: name: Rosid, Mochamad Alfan
Publisher: name: figshare
Year: 2016
Subjects: subject: Applied Computer Science
subject: 80607 Information Engineering and Theory
subject: FOS: Computer and information sciences

description: this paper propose centroid based classifier with TF-IDF-ICF fitur to for classifying text complaint on e-complaint aplication on universitas muhammadiyah sidoarjo
The Norwegian Orca ID-Catalogue. (2016). Version 2.
Creators: name: Jourdain, Eve
name: Karoliussen, Richard
Publisher: name: figshare
Year: 2016
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: The catalogue presents an overview of killer whale individuals that frequent coastal waters of northern Norway. Since the photographic-identification study is an ongoing project, the catalogue is regularly updated as new individuals are discovered. The latest version should be considered as a disclaimer of the previous ones.
Attenuating Racial Stereotypes Through Babyfacedness: A Replication and Extension of the Teddy-Bear Effect
Creators: name: Jin, Andrew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Facial features seemingly should not affect leadership assessments, yet research has consistently shown instant and robust judgments on physical appearance. Babyfacedness, a central attribute of facial inference, was originally found to be harmful for leaders. Through a survey of full-time employees in the United States (n = 269), non-White CEOs’ (Black, East Asian, and South Asian) increased babyfacedness was linked to higher leadership assessments mediated by warmth. This increased babyfacedness acted as a disarming mechanism by attenuating stereotypical perceptions of threat of non-White leaders. These findings stood despite non-White people being rated categorically less warm than White people in a separate survey of 50 participants. Collectively, these findings suggest non-White CEOs benefit from cues of warmth to compensate for racial stereotypes. Theoretical and practical implications, as well as future directions, are offered in the discussion section.
The Norwegian Orca ID-Catalogue. (2016)
Creators: name: Jourdain, Eve
name: Karoliussen, Richard
Publisher: name: figshare
Year: 2016
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: The catalogue presents an overview of killer whale individuals that frequent coastal waters of northern Norway. Since the photographic-identification study is an ongoing project, the catalogue is regularly updated as new individuals are discovered. The latest version should be considered as a disclaimer of the previous ones.
Born to Die: An Examination of Personal and Environmental Risk Factors Surrounding Capital Offenders on California’s Death Row.
Creators: name: Peterson, Isabella
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: This paper examines the role of risk factors as contributing agents to the severity of crimes that lead to death sentences in California. It was hypothesized that the more risk factors an individual was exposed to, the more severe their crime would be.  A crime severity scale was constructed from Michael H. Stone's "Gradations of Evil" scale and used to categorize the heinousness of offender's crimes. Risk factor information was obtained from California census data as well as Appellant Opening and Respondent Briefs. Sexual abuse and exposure to violence were found to be predictors of crime severity. Additionally, exposure to criminal activity was negatively associated with crime severity. Neglect was also found to be an important factor both on its own and even more so in its interaction with exposure to substance abuse. The results overall demonstrated that interactions between environmental and personal factors have an increased effect than the two factors on their own, and that the two demonstrate a moderating effect on one another in their interaction.
Processing temporal presuppositions: an event-related potential study
Creators: name: Jouravlev, Olessia
name: Stearns, Laura
name: Bergen, Leon
name: Eddy, Marianna
name: Gibson, Edward
name: Fedorenko, Evelina
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The ability to efficiently process presuppositions, which contain information that the speaker believes to be in the background to the conversation, is essential for effective communication. To get a deeper understanding of the nature and the time-course of temporal presupposition processing, we examined event-related potential evoked by the word again in two types of sentence contexts. The word again was presented in contexts that supported a presupposition (e.g. Jake had tipped a maid at the hotel once before. Today he tipped a maid at the hotel again … ) or violated it (e.g. Jake had never tipped a maid at the hotel before. Today he tipped a maid at the hotel again … ). The presupposition violation was associated with increased amplitudes of the P3b/P600 but not the N400 component. We argue for the centrality of the P3b/P600 component for presupposition processing. These findings demonstrate rapid integration of lexical presuppositions with contextual knowledge.
The role of morphological markedness in the processing of number and gender agreement in Spanish: an event-related potential investigation
Creators: name: Bañón, José Alemán
name: Rothman, Jason
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Current morphological theory assumes that feature values, such as masculine and feminine or singular and plural, are asymmetrically represented. That is, one member of the opposition (e.g. feminine for gender, plural for number) is assumed to be marked, and the other one, unmarked. The present study examines how these asymmetries impact agreement resolution in Spanish. Agreement was manipulated between a noun acting as head of a relative clause and an adjective located inside the relative clause (e.g. catedral que parecía inmensa “cathedral that looked huge”). Half of the nouns were feminine (marked) and the other half, masculine (unmarked). Half of the nouns were used in the plural (marked) and the other half, in the singular (unmarked). Twenty-seven Spanish native speakers read 240 sentences while their brain activity was recorded with electroencephalography and performed a grammaticality judgment. Results showed that both number and gender violations elicited a central-posterior P600, a component associated with syntactic repair, and a late anterior negativity, argued to reflect working memory costs. Only the P600 was affected by markedness. It started earlier for violations where the mismatching feature was marked. Moreover, it was larger for errors where the mismatching feature was marked, although this amplitude modulation only emerged for number, possibly due to differences in how number and gender cues were realized (i.e. both masculine and feminine showed overt inflection, but singular was uninflected relative to plural). These results suggest that the parser is sensitive to markedness asymmetries in the course of online processing.
Do morphemes matter when reading compound words with transposed letters? Evidence from eye-tracking and event-related potentials
Creators: name: Stites, Mallory C.
name: Federmeier, Kara D.
name: Christianson, Kiel
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: The current study investigates the online processing consequences of encountering compound words with transposed letters (TLs), to determine if cross-morpheme TLs are more disruptive to reading than those within a single morpheme, as would be predicted by accounts of obligatory morpho-orthopgrahic decomposition. Two measures of online processing, eye movements and event-related potentials (ERPs), were collected in separate experiments. Participants read sentences containing correctly spelled compound words (cupcake), or compounds with TLs occurring either across morphemes (cucpake) or within one morpheme (cupacke). Results showed that between- and within-morpheme transpositions produced equal processing costs in both measures, in the form of longer reading times (Experiment 1) and a late posterior positivity (Experiment 2) that did not differ between conditions. Findings converge to suggest that within- and between-morpheme TLs are equally disruptive to recognition, providing evidence against obligatory morpho-orthographic processing and in favour of whole-word access of English compound words during sentence reading.
Things that Live in My Stomach
Creators: name: Donnan, Rachel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: "Things that Live in My Stomach" is a series of essays written by Rachel Donnan. The essays reference both the recent and distant past of her family, who immigrated to America from the Philippines in the 1970s, as well as her shared past with Asian American history. Donnan envisions her history as different things that live in her stomach, such as truth, the untruth, family oral histories, and even teeth.
Leader Reactions to Their Own Gender-Based Image Threat: Why Leaders React Functionally and Dysfunctionally
Creators: name: Fleri, Abigail
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Leadership literature has long explored the impacts of leader gender and behaviors on subordinate perceptions; however, it lacks a nuanced understanding of how these factors impact leaders’ experiences in the workplace. Furthermore, while previous research has established the existence of strong gender norms, it has not exhaustively explored the impact of these norms on leader image and subsequent behavior. In this thesis, I argue leaders respond to gender-based image threat in one of two ways: functionally or dysfunctionally. To test this proposal, I implemented a correlational study design, surveying leaders across multiple time periods, to assess leader perceptions and behaviors. This thesis finds that while gender-role inconsistent behavior does not significantly affect image threat, self-regulation depletion does and serves as a potential mechanism by which leaders who behave gender-inconsistently experience image threat. Furthermore, the results showed that image threat is significantly and negatively related to functional leader behaviors and significantly and positively related to dysfunctional leader behaviors, providing important insights into leaders’ experiences.
Modelling verb selection within argument structure constructions
Creators: name: Matusevych, Yevgen
name: Alishahi, Afra
name: Backus, Ad
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: Plant Biology

description: This article looks into the nature of cognitive associations between verbs and argument structure constructions (ASCs). Existing research has shown that distributional and semantic factors affect speakers' choice of verbs in ASCs. A formal account of this theory has been proposed by Ellis, N. C., O'Donnell, M. B., & Römer, U. [(2014a). The processing of verb–argument constructions is sensitive to form, function, frequency, contingency and prototypicality. Cognitive Linguistics, 25, 55–98. doi:10.1515/cog-2013-0031], who show that the frequency of production of verbs within an ASC can be predicted from joint verb–construction frequency, contingency of verb–construction mapping, and prototypicality of verb meaning. We simulate the verb production task using a computational model of ASC learning, and compare its performance to the available human data. To account for individual variation between speakers and for order of verb preference, we carry out two additional analyses. We then compare a number of prediction models with different variables, and propose a refined account of verb selection within ASCs: overall verb frequency is an additional factor affecting verb selection, while the effects of joint frequency and contingency may be combined rather than independent.
Dances of Infection
Creators: name: Gamez, Isabella
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Outbreaks of disease are often repetitive and cyclical in nature. Even more, disease is a longstanding theme in human history and can vastly impact the culture of the time. Despite the vastly different settings and contexts, there is still much we can relate to with our 14th century peers. Killing 30-50% of the population, the Black Death defined the art and writing of the 14th century. Focusing on the common ground that disease provides, the artist researched historical works from the Black Death, and recontextualized those with our modern understanding of germ theory. Through this process, the artist creates a dialogue with these 14th century ideas and artistic motifs like the Danse Macabre, the deathbed scene, and the concept of miasma. The installation consists primarily of two elements: the layered mural of prints along the wall and the constructed imitation of a 14th century poster bed. Repeated woodcut prints are broken up by and interspersed between smaller, layered prints. Similarly, the images themselves are often dense with detail and visual signifiers. Using the constant symbols of rats, fleas, bacteria, and lavender, the repetition of imagery creates a cyclical and narrative structure within the installation. The installation itself then reflects the cyclical nature of disease and the often chaotic, crowded settings that encouraged the spread of the plague. This culminates at the poster bed, where the viewer is asked to engage with and reflect on a scene from the Black Death. Through this installation, a narrative of the cycle of infection emerges and as one walks along the installation, they are asked to engage with that narrative. Ultimately, infectious diseases will continue as a mainstay in the human experience. As such, it is essential to continue discussing past outbreaks and finding new ways to learn from them.
title: OFROM: interview avec unine11c05m
Creators: name: Delafontaine, François
name: Claivaz, Amélie
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.5527q481.v2#c1526a90b1b994c85626402b2452508f78154575
Croft Cottage Dendro-dated.
Creators: name: Jennings, Nina
Publisher: name: Archaeology Data Service
Year: 2013

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 8, 254-254
description: In the 2007 volume of these Transactions the author gave an account of Croft Cottage, Burgh-by-Sands. Samples from the house have now been examined and a dendrochronological date of AD 1510 has been ascribed. This makes it the fourth true longhouse in the Solway Plain to have been dated, and it is also the third-oldest standing clay dabbin to be identified.
Australia's capabilities versus the region
Creators: name: Kopp, Carlo
Publisher: name: Monash University
Year: 2016
Subjects: subject: 160604 Defence Studies
subject: FOS: Political science

description: Pages 3 and 5 not included. Advertising material only.
Defence Today, vol. 9, no. 5 (2012), p. 2-6
Copyright. Carlo Kopp
Transcriptional profiling and metabolic modeling reveal a role for c-di-AMP in regulation of sporulation, central metabolism, and transport systems in C. difficile
Creators: name: Gamez, Isabella
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Cyclic di-adenosine monophosphate (c-di-AMP) is an essential second messenger signaling molecule known to regulate numerous processes including potassium homeostasis and osmolarity, central metabolism, and sporulation. C-di-AMP synthase and regulator genes, dacA and dacR, have been identified in Clostridioides difficile, however, the function of c-di-AMP remains largely uncharacterized. As such, we aimed to investigate the impact of c-di-AMP in C. difficile. Using RNA-seq, metabolic modeling, and a gene set network score analysis, we investigated the effects of the overexpression of dacA and dacAR. We found that c-di-AMP broadly impacts the C. difficile transcriptome, altering the expression of genes involved in sporulation, central metabolism, and transport systems. Simulating metabolic flux further supported the focus on transport systems and emphasized the conversion of various sugars to D-glucose 6-phosphate. Finally, the network score validated the connection between metabolism-based genes and the metabolic network. Our findings provide novel insight into the role of c-di-AMP in C. difficile as well as testable hypotheses for future studies.
A Medieval Road in Ulverston.
Creators: name: Whitehead, Samuel
name: Elsworth, Daniel W
Publisher: name: Archaeology Data Service
Year: 2013

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 8, 250-254
description: An area of cobbling thought to be a roadway or yard surface was revealed during archaeological evaluation at the north-eastern edge of the core of medieval Ulverston. A single piece of medieval pottery was recovered from the feature, and residual medieval sherds came from a later soil horizon directly overlying the surface. A larger area was subsequently excavated. The feature appeared to represent a well-used path or track and was a significant discovery as it is, to date, the only confirmed medieval feature identified through archaeological excavation in Ulverston. LD
Wellbeing Index Portal
Creators: name: Azzopardi, Joel
name: Briguglio, Marie
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Wellbeing in Malta
subject: Data mining
subject: Life Satisfaction

description: The wellbeingindex.mt online portal is a core deliverable of the Wellbeing INDEX project, and serves as a one-stop-shop of Wellbeing Indicators, Networking, Data, Exploratory studies and eXchange (INDEX) developed.  The Wellbeing INDEX project is a strategic and over-arching initiative, led by the Malta Foundation for the Wellbeing of Society in collaboration with the University of Malta, and aims to pave the way for the measurement of wellbeing in Malta and evidence-based wellbeing policy.

The portal provides links to relevant datasets and publications, and also provides a number of dashboards that visualise indicators on satisfaction (in different life domains) and affect (positive and negative emotions) in Malta.
Medieval remains on Boroughgate, Appleby.
Creators: name: Whitehead, Samuel
name: Elsworth, Daniel W
Publisher: name: Archaeology Data Service
Year: 2013

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 8, 246-249
description: An evaluation was undertaken prior to submission of a planning application. A considerable number of features typically associated with plots, yards and gardens were recorded, the earliest probably originating in the 12th century, and large quantities of medieval artefacts were recovered. Post-medieval features were also present. It was concluded that the site had enormous potential to reveal further information about the development of medieval Appleby. LD
A Flake of a Stone Axe from Ash Fell.
Creators: name: Clare, Tom
Publisher: name: Archaeology Data Service
Year: 2013

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 8, 241-241
description: The finding of a flake from a polished stone axe at Ash Fell, near Ravenstonedale, has extended the geographical spread of flakes interpreted as resulting from the use of axes to work timber. LD
Killing Me Softly: A Memoir of a Failed Childhood Dream
Creators: name: Renaud, Ciara
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Killing Me Softly is a memoir about growing up doing ballet. It deals with themes of girlhood, discovering and forming an identity, relationships to family and self, and what it means to fall in and out of love with an art form.
Investigation of part of the High Street Roman Road in Kentmere.
Creators: name: Whitehead, Samuel
name: Elsworth, Daniel W
Publisher: name: Archaeology Data Service
Year: 2013

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 8, 241-246
description: An evaluation and topographic survey were carried out prior to repair work to a footpath that follows the line of the High Street Roman Road. Three main areas of earthwork features were recorded, whilst the evaluation trenches revealed a surface and other features that seemed likely to represent remains of the road. The route of the road south of the survey area has been subject to some debate. Observations made during the project and a reassessment of documentary sources suggested that one potential route for the road may be more likely than another. LD
The Relationship Between Estrogen, Stressful Life Events, and Irritability in Perimenopausal Women
Creators: name: Prakken, Alexander
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: During the menopause transition, the likelihood of clinically significant depressive symptoms increases two-to-four-fold. Irritability, defined as a lowered threshold for experiencing anger and/or aggression, is a cardinal symptom of perimenopausal depression. Stressful life events and sensitivity to estradiol fluctuations have been shown to be risk factors in the development of mood symptoms in early and middle menopause, but how irritability specifically is affected 
by estradiol changes is unknown. In this study, we sought to characterize the relationship between estrone-3-glucuronide (E1G), a urinary metabolite of estradiol, and irritability in perimenopausal women, and to examine whether the presence of stressful life events moderates that relationship. Nineteen perimenopausal women, ages 45-53, were assessed daily for irritability and provided every other day urinary E1G samples. Severely stressful life events (SSLEs) were assessed once at enrollment. Results from linear regression models demonstrated a trend towards a positive association between SSLEs and irritability (F(3,62) = 2.1, P = 0.066) and a trend toward an inverse association between weekly E1G exposure and irritability in women who had one or more recent SSLEs (F(3,62) = 2.1, P = 0.073). No significant associations were observed between weekly E1G exposure and overall depressive symptomatology (all Ps > 0.38). Though not statistically significant, these trends are consistent with the known beneficial mood effects of estradiol and indicate the possibility of an effect on irritability specifically. Future considerations include a larger sample size, assessment of the effects of estradiol 
therapy on perimenopausal irritability, and the use of neurophysiologic techniques to define associated central nervous system processes.
title: OFROM: interview avec unine11c04m
Creators: name: Delafontaine, François
name: Claivaz, Amélie
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.cb6f5731.v2#d6ebe40665abb63f0ca1f07293b1f955507d4a74
Air superiority 'game changers': T-50 PAK-FA and J-20
Creators: name: Kopp, Carlo
Publisher: name: Monash University
Year: 2016
Subjects: subject: 160604 Defence Studies
subject: FOS: Political science

description: Defence Today, vol. 9, no. 4 (2012), p. 34-35
Copyright. Carlo Kopp.
A therapeutic exercise programme for patients with surgical repair after proximal hamstring avulsion: a case report with 3-year follow-up
Creators: name: Heléne Engberg Skaara
name: Moksnes, Håvard
name: Grønvold, Didrik
name: Koppang, Ole Leif
name: Stuge, Britt
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Background: Surgery is commonly recommended for patients with proximal hamstring avulsion. Rehabilitation is important, but there is limited knowledge of optimal rehabilitation post-surgery. The purpose of this case report was to describe and evaluate a therapeutic exercise programme for a patient with acute surgical repair after proximal hamstring avulsion. Case presentation: A 53-year-old man was injured while waterskiing. Magnetic resonance imaging (MRI) verified a proximal hamstring avulsion, and he had surgical treatment eight days later. Seven weeks after surgery, he started a therapeutic exercise programme. Performance-based tests and self-reported questionnaires were performed 3, 6, 12 and 42 months post-surgery. MRI was performed after 12 and 42 months. Results: At 6 months, the patient had returned to previous level of activity but reported some fear for re-injury. He scored 92% (74 points) on the Lower Extremity Functional Scale and estimated his recovery to be 100% on the Proximal Hamstring Injury Questionnaire. The isokinetic muscle strength test for knee flexion showed a leg symmetry index of 99%. MRI at 12 months showed an intact tendon with good congruence. Conclusion: The described therapeutic rehabilitation programme for this patient resulted in normalized physical function and he returned to pre-injury activity level at 6 months.
FANCA-deficient cancer cells are sensitized to PARPi and ATRi by homologous recombination-independent mechanisms
Creators: name: Ellington, Simon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: PARP inhibitors (PARPi) are a class of DNA damage-inducing drugs currently used in the clinic to treat cancers with mutations in BRCA1/2, which show elevated sensitivity to PARPi. This PARPi sensitivity is traditionally thought to be mediated by deficiency in homologous recombination (HR) — an important DNA repair process — conferred by loss of BRCA1/2. As such, HR-deficiency is currently the sole criterion for selecting patients for PARPi treatment. However, the complete set of mechanisms underlying sensitivity to PARPi, as well as the types of genetic alterations which may confer PARPi sensitivity, remain poorly understood. Through an in vivo CRISPR screen, we identified loss of FANCA as synthetic lethal with PARPi, indicating that tumors deficient in the DNA damage response (DDR) gene FANCA are more sensitive to PARPi than control tumors. Using viability assays, we demonstrated that loss of FANCA confers sensitivity to PARPi in breast and lung cancer cell lines and further showed that PARPi and ATR inhibitors (ATRi) act synergistically to kill FANCA knockout (KO) cancer cells. By detecting nuclear markers of DDR signaling pathways, we showed that following treatment with PARPi, FANCA KO cancer cells display no impairment of HR repair compared to FANCA WT cells.  Furthermore, we demonstrated that under DNA replication stress, FANCA KO breast cancer cells display increased PARP1 signaling compared to FANCA WT cells, suggesting a potential moonlighting function of FANCA as a backup to PARP1 in the cellular response to replication stress. These findings demonstrate alternative mechanisms of PARPi sensitivity outside of HR deficiency and provide a rationale for clinical investigation of PARPi activity in patients with FANCA-mutant cancers, which make up 4% of metastatic breast cancer cases.
title: OFROM: interview avec unifr18a02d
Creators: name: Delafontaine, François
name: Delpedro, Anouk
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.b6f9x0w9.v2#2eaf257e68e515d052f853fdbb433460d1b6264d
Prototokoi: The Epistemic Authority of First-Time Mothers in Early Medicine
Creators: name: Thompson, Hannah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: The Hippocratic Corpus, as a collective, is the largest body of surviving early Greek texts, encompassing over sixty ancient medical treatises. Written throughout the fifth and fourth century BCE, these texts give testament to their authors’ understanding of the human condition – birth to death, health to disease, body to soul. Within the breadth of this corpus, several works are dedicated to gynecological practices that pertain to both reproductive health and broader diseases. Though the focus of these gynecological works specifically centers around narratives of women, these treatises were written exclusively by a collection of male physicians. Thus, the stories and portrayals of women in the Hippocratic Corpus can only really be understood through the lens of their male medical practitioners. In an effort to better understand the role of women as patients but also, perhaps, as healers, this project reviews cases of women discussed within gynecological treatises in ancient literature. This thesis specifically focuses on their use as sources of knowledge and their roles as medical authorities of their own bodies and experiences. Upon adding further epistemological distinctions to the framework in which we categorize the women in these texts, this thesis introduces a category of women that have not yet been taken into account: the 'prototokoi', or first-time mothers, who occupy a biological and cultural transitional stage between 'parthenos' and 'gune'. Ultimately, in presenting the transitional state of the 'prototokoi' and the problems this causes for their epistemic authority, this thesis both contributes to the existing scholarship on women as sources of knowledge in the Hippocratic Corpus and challenges the binary distinction between women of experience and those of inexperience.
Money, Money, Money: An Exploration on the Impact of Rising Ticket Prices on Consumer Perceptions
Creators: name: Brown, Colleen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: 
Concerts are a key focal point of the music industry. They connect artists and fans to create value for both. Ticket prices for concerts, however, have increased to a point that has caught the attention of mainstream media. To analyze the impact of ticket pricing trends on consumers’ interest in concerts and sentiment towards the artists themselves, this study surveys 213 students to explore their interactions with ticket markets and their perceptions of their favorite musicians. Results from this study show that while consumers are often upset by prices that exceed their predetermined thresholds, their opinions of their favorite musicians do not negatively change as a result. Notably, respondents often considered themselves price sensitive, yet often purchased tickets above their self-imposed price threshold. The disconnect between consumers’ price evaluations, sentiment towards artists, and actual purchasing behavior has significant implications for price setters in the music and concert industry.
Taking the High Road: Moral Identity and Individual-Specific Determinants of Prosocial Purchasing Behavior
Creators: name: Sen, Dishita
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024
Subjects: Social responsibility of business

description: Studies show that companies and consumers are increasingly interested in corporate social responsibility, but the costs associated with responsible production and sustainability pose challenges. Stakeholders need to understand the tradeoff between price and social responsibility and understand what makes consumers willing to pay higher prices for prosocial products. This study surveys 242 consumers’ propensity to make a prosocial purchasing decision and the motivating and mediating factors that affect the decision-making process. Direct effects of demographic factors and visibility of purchases were not found, but exploratory results show a significant positive relationship between individuals’ Moral Identity Questionnaire (MIQ) scores and likelihood to make a prosocial purchasing decision; a significant negative relationship between MIQ score and price as a motivator away from prosocial decisions; and a significant influence of MIQ on peers’ perception as a motivator for behavior regardless of public visibility. These results indicate that consumers’ predisposed moral values significantly positively affect propensity to purchase prosocial products.
The Use of the Emotion Association Task to Measure Emotional Granularity
Creators: name: St. Denis, Carson
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Individuals differ in their emotional expertise. Emotional granularity is one facet of emotional 
expertise and represents the ability to conceptualize a broad range of emotions with specificity. 
Measures of emotional granularity have continued to evolve since the 1970s. Here, we introduce 
a novel measure of emotional granularity using representational similarity analysis and data from 
a novel property association task, the Emotion Association task (EAT). We compare emotional 
granularity, as derived from the EAT, to several convergent and divergent measures. Namely, we 
compared scores on the EAT to classical measures of emotion granularity collected via self-report 
and day reconstruction as well as to a number of relevant individual difference measures 
pertaining, broadly, to emotion. We found that the EAT scores converged with components of a 
similar task, the Day Reconstruction Method (DRM). The EAT diverged from common methods 
that test granularity on body beliefs, alongside a survey measure of granularity known as the Range 
and Differentiation of Emotional Experience Scale (RDEES). Overall, the findings suggest that 
the EAT is a powerful tool to measure emotional granularity, while being far less time and resource 
intensive than competing measures
Development of a Three-Dimensional Endometrial Model to Examine Factors Affecting Endometrial Function
Creators: name: Broyhill, Sarah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Endometriosis, a reproductive disease affecting one in ten women, is characterized by debilitating pain, excessive menstrual bleeding, and infertility. Elevated levels of certain proteins, such as pro-inflammatory cytokines and SIRT1, are seen in endometrial tissue from endometriosis patients and are thought to be contributing factors to infertility by negatively affecting the endometrium's ability to decidualize prior to implantation. Given the inherent limitations of studying the human endometrium in vivo, there is a need to develop an in vitro model to study the endometrium and its interaction with trophoblast cells that will form the placenta. These studies aimed to develop one part of a three-dimensional model of the endometrium using a semi-synthetic, derivatized collagen matrix, GelMA, and endometrial stromal cells. An essential function of endometrial cells is decidualization, a conversion from mesenchymal-like to epithelial-like cells reflected by a significant change in gene expression, including a marked increase in prolactin (PRL) production. Without decidualization, a mammalian pregnancy cannot be established. Optimization of the 3-D model involved RT-qPCR to measure PRL gene expression with or without combined treatment with decidualization factors (estradiol (10E-8 M), medroxyprogesterone (10E-6 M), and cAMP (10E-6 M)). We also compared that response to stromal cells on plastic in 2-D culture. Decidualization was successfully induced in the 3-D culture conditions in a manner similar to that seen on plastic (and in vivo). The development of this model opens the door for future investigations aimed at better understanding the molecular functions of the endometrium and the etiologies underlying idiopathic infertility, as well as helping discover novel pharmacological targets to treat infertility in women with endometriosis.
From Fossil Fuels to Renewable Energy: Navigating the Workforce Transition in the U.S. Energy Sector
Creators: name: Gu Wei Tian Xie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: The transition towards renewable energy sources in the United States represents a crucial shift in the pursuit of green energy, which carries considerable implications for the labor market within the energy sector for extraction workers. This study focuses on the transition of human capital from non-renewable to renewable energy sectors in the energy industry. Utilizing comprehensive data from the Occupational Information Network (O*NET), this study analyzes cognitive and non-cognitive worker requirements between extraction and renewable occupations. The results indicate that requirements for renewable energy occupations are more dissimilar from extraction occupations compared to Career Starters. While the path is not uniformly straightforward, specific extraction occupations are identified as very well aligned to renewable energy occupations with cognitive and non-cognitive requirements. These select pipelines suggest an opportunity for fostering a seamless transition to align workforce development with environmental and energy goals, offering a hopeful vision for the future.
Elucidating Psilocin Effects on Interoceptive Circuitry within the Insular Cortex
Creators: name: Foglesong, Mia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Psilocybin holds promising therapeutic potential in treating psychiatric disorders. However, despite clinical studies showing psilocybin’s therapeutic action in treating persistent resistant depression and substance use disorder, the cellular mechanisms and brain region-specific effects of psilocybin’s active metabolite, psilocin, remain poorly understood. One brain region of interest is the insular cortex (IC), which serves as an integrative hub for sensory signals from within (interoceptive) and from our environment (exteroceptive), and changes in morphology and connectivity have been linked to several psychiatric disorders. Our study used multilevel approaches to further understand psilocin’s action within the IC. We conducted qualitative analyses on connectivity between the anterior cingulate cortex and IC, as well as 5-HT2A receptor density within different regions of the IC using a novel transgenic mouse line. We measured c-Fos, a neuronal activity marker, within distinct anatomical areas of the IC following acute injection of psilocin. Additionally, we measured calcium dynamic changes in vivo within the left hemisphere of the anterior IC (aIC) using fiber photometry that was paired with aversive air-puff stimuli. We found that the aIC has the densest inputs from the anterior cingulate cortex, highest 5-HT2A expression, and shows reduced c-Fos expression after psilocin administration when compared to other IC subregions. Preliminary analyses of fiber photometry recordings showed that the aIC responded to aversive stimuli and that psilocin exhibits slight anxiolytic effects. Overall, our findings provide insights into the neurobiological mechanisms behind psilocin’s therapeutic effects.