cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
In silico and bio assay of juvenile hormone analogs as an insect growth regulator against Galleria mellonella (wax moth) – Part I
Creators: name: Sharma, Priyanka
name: Thakur, Sunil
name: Pamita Awasthi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology

description: Juvenile hormone (JH) analogs are nowadays in use to control harmful pests. In order to develop new bioactive molecules as potential pesticides, we have incorporated different active structural features like sulfonamide, aromatic rings, amide group, and amino acid moiety to the base structure. We have screened a series of designed novel JH analogs against JH receptor protein (jhbpGm-2RCK) of Galleria mellonella in comparison to commercial insect growth regulators (IGRs) – Pyriproxyfen (T1) and Fenoxycarb (T2). All analogs exhibit the binding energy profile comparable to commercial IGRs. Based upon these results, a series of sulfonamide-based JHAs (T3–T8) as IGRs have been synthesized and characterized. Further, the efficacy of synthesized analogs (T3–T8) and commercial IGRs (Pyriproxyfen and Fenoxycarb) has been assessed against fourth instars larvae of G. mellonella under the laboratory conditions. LC50 values of all the analogs (T1–T8) against the fourth instars larvae were 9.99, 10.12, 24.76, 30.73, 38.45, 34.15, 34.14, 19.48 ppm and the LC90 153.27, 131.69, 112.15, 191.46, 427.02, 167.13, 217.10, 172.00 ppm, respectively. Among these analogs, N-(1-isopropyl-2-oxo-3-aza-3-N-ethyl-pentanyl)-p-toluene sulfonamide (T8) and N-(1-isopropyl-2-oxo-3-aza-3-N-ethyl-pentanyl) benzene sulfonamide (T7) exhibited the good pest larval mortality at different exposure periods (in hours) and different concentrations (in ppm) in comparison to in use IGRs- T1 and T2. Bio assay results are supported by docking at higher concentration. The present investigation clearly exhibits that analog T8 could serve as a potential IGR in comparison to in use IGRs (T1 and T2). The results are promising and provide new array of synthetic chemicals that may be utilized as IGRs.
Spatial distribution and molecular diversity of archaeal communities in the extreme hypersaline meromictic Brâncoveanu Lake (Transylvanian Basin, Romania)
Creators: name: Adrian-Ştefan Andrei
name: Baricz, Andreea
name: Păuşan, Manuela
name: Muntean, Vasile
name: Sicora, Cosmin Ionel
name: Alexe, Mircea
name: Rakosy-Tican, Elena
name: Banciu, Horia Leonard
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Dating from the Middle Miocene, the massive halite deposits lying beneath the Transylvanian Basin (Central Romania) have been valuable mineral resources quarried for millennia. Among the numerous hypersaline pit lakes resulted from this mining, Brâncoveanu Lake is unique by its extreme salinity. Assessment of physicochemical variables, water chemistry, and trophic status indicated that Brâncoveanu Lake is a permanently stratified, pH-neutral, NaCl-rich, and eutrophied system. We investigated the abundance, molecular diversity, and vertical distribution of archaeal community by culture-independent approaches. Additionally, most relevant environmental parameters shaping the archaeal community composition were evaluated by statistical methods. Archaea appeared to largely outnumber Bacteria and altogether with a great prevalence of Halobacteriaceae-related sequences could imply a major contribution of this group to the biogeochemical carbon turnover. Fairly distinct composition of archaeal communities was found to reflect the lake physicochemical stratification. Among the limnological factors, salinity and oxygen showed significant impact on determining composition and structure of archaeal assemblages. Furthermore, Brâncoveanu Lake might harbor novel microorganisms such as members of the recently described phylum Nanohaloarchaeota. Overall, this study reported the occurrence of halophilic Archaea in a little explored hydrogeochemical system and provided a better insight into geomicrobiology of meromictic hypersaline pit lakes.
ON-MERRIT D1.2 Data Management Plan
Creators: name: Metzler, Hannah
name: Pontika, Nancy
name: Fessl, Angela
name: Gyawali, Bikash
name: Wieser, Bernhard
name: Schmidt, Birgit
name: Klebel, Thomas
name: Ross-Hellauer, Tony
Publisher: name: Zenodo
Year: 2020
Subjects: ON-MERRIT
Data Management Plan
FAIR principles
Responsible Research and Innovation

description: This Data Management Plan (DMP) contains a description of all datasets to be collected, generated or re-used as part of ON-MERRIT’s research activities.
 This includes, firstly, the purpose of data collection (i.e. research questions), data origin, type, sharing and utility, as well as expected file size and format. Datasets for ON-MERRIT include primary data collected via surveys, interviews and workshops, as well as compiled, processed data generated from the knowledge graph Microsoft Academic Graph, the CORE aggregator, and Google Patents Public Data.
 Second, this DMP outlines measures taken to ensure compliance with the FAIR data principles.1 Most datasets generated during ON-MERRIT will be made findable and openly accessible (whenever possible, depending on data protection requirements) via the repository Zenodo together with detailed metadata and a digital object identifier. To make data interoperable, the consortium will use Open Source software and file formats wherever possible. To enable and stimulate re-use of data, analysis code will be shared via GitHub, appropriate open licences (CC-BY or similar) will be assigned, and quality is ensured via internal review processes.
 Third, the DMP describes the allocation of resources for data management, storage solutions and back-up plans during the project, long-term retention and data security, ensured via encryption and password protection. It finishes with a description of technical and organizational measures put in place for the protection of personal data, including collection and internal sharing of personal data (where necessary), anonymisation and pseudonymisation techniques used before making data openly accessible, and informed consent procedures.
 This DMP is a living document that will be regularly updated by all partners. At a minimum, it will be updated once after the end of the first reporting period (30 September 2020, report deadline 30 November 2020), at the end of phase 2 (30 September 2021) and, if additional changes are required, one final time before the final review (3 March 2022).
Elucidation of structural and functional properties of albumin bound to gold nanoparticles
Creators: name: Mariam, Jessy
name: S. Sivakami
name: P.M. Dongre
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Nanoparticle–albumin complexes are being designed for targeted drug delivery and imaging. However, the changes in the functional properties of albumin due to adsorption on nanoparticles remain elusive. Thus, the objective of this work was to elucidate the structural and functional properties of human and bovine serum albumin bound to negatively charged gold nanoparticles (GNPs). Fluorescence data demonstrated static quenching of albumin by GNP with the quenching of buried as well as surface tryptophan in BSA. The binding process was enthalpy and entropy-driven in HSA and BSA, respectively. At lower concentrations of GNP there was a higher affinity for tryptophan, whereas at higher concentrations both tryptophan and tyrosine participated in the interaction. Synchronous fluorescence spectra revealed that the microenvironment of tryptophan in HSA turned more hydrophilic upon exposure to GNP. The α-helical content of albumin was unaltered by GNP. Approximately 37 and 23% reduction in specific activity of HSA and BSA was observed due to GNP binding. In presence of warfarin and ibuprofen the binding constants of albumin–GNP complexes were altered. A very interesting observation not reported so far is the retained antioxidant activity of albumin in presence of GNP i.e. we believe that GNPs did not bind to the free sulfhydryl groups of albumin. However enhanced levels of copper binding were observed. We have also highlighted the differential response in albumin due to gold and silver nanoparticles which could be attributed to differences in the charge of the nanoparticle.
The Explorer Islamabad (Volume 2 , Issue 2)
Creators: name: Explorer-Islamabad, The
Publisher: name: figshare
Year: 2016
Subjects: subject: Anthropology
subject: FOS: Sociology
subject: 140299 Applied Economics not elsewhere classified
subject: FOS: Economics and business
subject: Archaeology
subject: 130101 Continuing and Community Education
subject: FOS: Educational sciences
subject: 140201 Agricultural Economics
subject: 140301 Cross-Sectional Analysis
subject: 130102 Early Childhood Education (excl. Maori)
subject: 140302 Econometric and Statistical Methods
subject: 140399 Econometrics not elsewhere classified
subject: 140202 Economic Development and Growth
subject: 140203 Economic History
subject: 140303 Economic Models and Forecasting
subject: Economics
subject: Education
subject: 140204 Economics of Education
subject: 130199 Education systems not elsewhere classified
subject: 140205 Environment and Resource Economics
subject: 140206 Experimental Economics
subject: 140208 Health Economics
subject: Geography
subject: 140207 Financial Economics
subject: 130103 Higher Education
subject: 140209 Industry Economics and Industrial Organisation
subject: 130105 Primary Education (excl. Maori)
subject: Sociology
subject: 140218 Urban and Regional Economics
subject: 140219 Welfare Economics

description: The Explorer Islamabad Volume 2, issue 1
ON-MERRIT D2.1 Dissemination and Valorisation Plan
Creators: name: Brinken, Helene
name: Metzler, Hannah
name: Pontika, Nancy
name: Correia, Antonia
name: Ross-Hellauer, Tony
name: Klebel, Thomas
Publisher: name: Zenodo
Year: 2020
Subjects: ON-MERRIT
Responsible Research and Innovation
Dissemination Strategy

description: ON-MERRIT investigates how and if current open and responsible research policies could worsen existing inequalities. The project targets an equitable scientific system that rewards based on merit rather than “cumulative advantage” (the so-called “Matthew Effect”). The concepts of Responsible Research & Innovation (RRI) and Open Science aim to shift academic culture towards transparency and participation in research processes. Yet making processes open will not per se drive re-use or participation unless also accompanied by the capacity to do so.
 In this Dissemination, valorisation and participation plan, ON-MERRIT describes how the project is raising awareness about existing inequities and disseminating results on how to address them. Following a general approach of PLAN, ACT, OBSERVE and REFLECT, ON-MERRIT initiated its communication activities by identifying academic communities, researchers, funders, industry, policy-makers and the society at large as target audience. Furthermore, we selected key results to be exploited and disseminated among these groups. The results include primary evidence and their summaries of (non-) existence of Matthew Effects in RRI, as well as policy briefings and recommendations for funders and institutions.
 ON-MERRIT uses formal and informal formats to disseminate results and ensure their uptake. On the one hand, the project team is publishing evidence in peer-reviewed journals, is releasing regular blog posts and has built a website. On the other hand, ON-MERRIT uses social media to interact with the community and plans to organize workshops and other activities to engage stakeholders throughout the project. The first actions included the launch of the project website, the creation of the project identity and a toolkit consisting of templates, guidelines and dissemination materials such as stickers and leaflets to support the outreach potential of each consortium partner.
 ON-MERRIT agreed on a set of key performance indicators (KPIs), such as social media interaction, number of policy briefings, blog posts and publications, to measure impact and success of communication activities. The Dissemination, valorisation and participation plan and the KPIs will be reviewed twice a year to ensure that all measures contribute to successful dissemination and that actions can be adapted if necessary.
Carnet nº 4, commencé à Novorossiïsk (p. 35)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: created: 19-4-1929
Electron donating capabilities and evidence for redox activity in low oxidation state iron complexes bearing bis(amidine)pyrimidylidene ligands
Creators: name: Hilan Z. Kaplan
name: Mako, Teresa L.
name: Wilding, Matthew J.T.
name: Li, Bo
name: Byers, Jeffery A.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Low valent iron complexes bearing bis(amidine)pyrimidylidene (or carbeno-diamidine, CDA) ligands have been synthesized and characterized by X-ray crystallography, Mössbauer spectroscopy, infrared spectroscopy, EPR spectroscopy, and DFT calculations. One electron reduction of (CDA)FeCl2 (1) resulted in formation of (CDA)FeCl (2), which demonstrated an unusual metal−N-heterocyclic carbene (NHC) interaction where a redox-noninnocent NHC participates in a one electron π-interaction with the metal center. This interaction renders the complex best described as a low spin iron(II) complex that is antiferromagnetically coupled to a singly reduced CDA ligand. Two electron reduction of 1 under an atmosphere of carbon monoxide resulted in the formation of the diamagnetic complex (CDA)Fe(CO)2 (3). Complex 3 demonstrated significantly lower CO stretching frequencies compared to previously reported bis(imino)pyridine and even bis(N-heterocyclic carbene)pyridine iron complexes, which reflects the significant σ-donating capabilities of the CDA ligands.
FEATURES OF MYOCARDIAL  INFARCTION  IN YOUNG WOMEN
Creators: name: Tashkenbaeva, E.N.
name: Madjidova, G.T.
name: Sunnatova, G.I
name: Mukumova, S.A.
Publisher: name: Zenodo
Year: 2024

description: It has been shown that the course of myocardial infarction in women, especially after 40 years, is characterized by the ¬severity of complications, such as cardiac rupture, cardiogenic shock, asystole, recurrent ventricular fibrillation and EMD, which provide a large percentage of deaths. The mortality rate of women is especially high in the fifth decade of life, and at the age of 50 to 59 years, the highest incidence of repeated large-focal necrosis was noted, while small-focal myocardial infarctions, including repeated ones, were detected in patients aged 45 to 55 years, which is more common than in women under 60 years of age.
On the Birch and Swinnerton-Dyer conjecture and ERG Theory
Creators: name: Wright, Nicholas R.
Publisher: name: figshare
Year: 2019
Subjects: subject: 10301 Numerical Analysis
subject: FOS: Mathematics

description: We prove the integrality and modularity of the Birch and Swinnerton-Dyer conjecture with ERG Theory. Inspection of the conjecture shows that it is a phenomenological model. Thus, a solution could be found through regression analysis. Numerical verification is possible through nominative determinism/visibility theory. By adding adaptive learning (AL) to the model, the model admits an important time variation in beliefs, which would be ruled out under rational expectations. Entropy can be given from a detailed molecular analysis of the system. In summary, perception consists of the selection, organization, and interpretation of stimuli. These factors affect the conduct of work. We include two inequalities on the log-volume change associated to appropriately chosen deformations.
A short note on contexts and chronology of the materials from Saidu Sharif, Amluk-dara, Gumbat and Barikot (Swat)
Creators: name: Olivieri, Luca Maria
Publisher: name: Restauro Archeologico
Year: 2019

description: The following note is meant to integrate the data of the materials discussed in three contributions published in this issue of «Restauro Archeologico» (Bonaduce et al., this issue; Festa, Pannuzi, this issue; Rosa et al., this issue; Zaminga et al., this issue)). The analysed materials were sampled from three Buddhist cultic complexes in the Swat Valley in the outer Gandharan region (nowadays in Pakistan). The three sites are Saidu Sharif I, Amluk-dara, and Gumbat. Other samples were taken from a votive chapel (Shrine 1023) of the urban settlement of Barikot in the Swat Valley. All the samples belong to the same chronological phase (3rd century CE).
description: Restauro Archeologico, Vol. 27 No. 1 (2019)
Geological overwiew of Gandharan sites and petrographical analysis on Gandharan stucco and clay artefacts
Creators: name: Rosa, Carlo
name: Theye, Thomas
name: Pannuzi, Simona
Publisher: name: Restauro Archeologico
Year: 2019

description: The Gandharan archaeological sites are mostly located in the Indus Suture Zone and in the lower Swat. In a recent past, scholars observed the use of local different type of schists to build buildings and sacred artworks. In this new research we highlighted the use of limestone for stucco artefacts and architectural decorations. This limestone is not a local rock in Swat but its main, ex- tended and closer outcrops are located in the mountains northwest of Islamabad. Indeed, through specific analyses carried out by our team, the compatibility of these outcrops with the rocks used for stucco artefacts and stucco decorations of buildings was observed. This stucco was made by a mixture of different kinds of local crushed rocks (i.e. schists and granites).
description: Restauro Archeologico, Vol. 27 No. 1 (2019)
ORCID iD Throughput in Publishing Workflows - Journal Article Tag Suite Conference (JATS-Con) Proceedings 2016 - NCBI Bookshelf.pdf
Creators: name: Haak, Laurel
Publisher: name: figshare
Year: 2016
Subjects: subject: 80401 Coding and Information Theory
subject: FOS: Computer and information sciences
subject: 80403 Data Structures
subject: Data Format
subject: Information Systems

description: Paper for JATS 2016 Conference, 12 April 2016. See paper for co-authors. Paper published by NLM as part of conference proceedings, available at http://www.ncbi.nlm.nih.gov/books/NBK350150/. Associated with conference presentation, available at 10.6084/m9.figshare.3172084.
Polychromy and gilding in the Gandharan sculptures from Pakistan and Afghanistan: samplings from Museum Guimet in Paris, Civic Archaeological Museum of Milan and Museum of Oriental Art of Turin
Creators: name: Pannuzi, Simona
name: Talarico, Fabio
name: Guida, Giuseppe
name: Rosa, Carlo
Publisher: name: Restauro Archeologico
Year: 2019

description: This paper will discuss the scientiﬁc results of a recent sampling of the polychrome and gilded stone, stucco and clay sculptures of Gandharan art not yet published. Four years ago, we had the opportunity to begin an articulated research project focused on the Gandharan polychrome stone and stucco sculptures, and in the last two years, thanks to a very limited grant, offered by the Italian Government to the Istituto Superiore per la Conservazione ed il Restauro (ISCR), we had the opportunity to develop a new research. This allowed us to investigate some important artefacts displayed in these Museums: the Archaeological Museum of Milan, the Museum of Oriental Art of Turin, the Museum Guimet in Paris. Moreover, we had the opportunity to take some archaeological samples from the new excavations of the Italian Archaeological Mission in Pakistan and the Italian Archaeological Mission in Afghanistan. In this new research we analysed the artistic technique of painting and gilding on sculptures of Gandharan art made in different materials (stone, stucco and clay). The results discussed in this paper comes from a notable number of chemical analyses (optical stero-microscope, SEM-EDS, micro-FTIR, micro-XRD and micro-Raman).
description: Restauro Archeologico, Vol. 27 No. 1 (2019)
The characterisation of paint binders in the polychromies and gildings of the Gandharan artworks
Creators: name: Bonaduce, Ilaria
name: Lluveras Tenorio, Anna
name: Andreotti, Alessia
name: Orsini, Sibilla
name: Colombini, Maria Perla
name: Dilillo, Marialaura
name: McDonnell, Liam Andrew
Publisher: name: Restauro Archeologico
Year: 2019

description: In a polychrome artefact, coloured paint layers are applied on architectural elements or sculptures. Paint layers are made up of the colour, which is most typically an inorganic pigment and, with the exception of frescos, an organic binder, which enables the pigment to be dispersed and applied with a brush. From an analytical point of view the characterisation of organic paint binders is very challenging: the organic matter represents a very small amount of the total weight of the sample which is very small and aged. In this paper we describe the analytical approach applied for the characterisation of samples collected from a selection Gandhara polychromies. The analytical strategies and techniques employed are described and examples of the results obtained are presented.
description: Restauro Archeologico, Vol. 27 No. 1 (2019)
Investigating gilding techniques on Gandharan stone sculptures and architectural components: a preliminary note
Creators: name: Zaminga, Marco
name: Angelini, Ivana
name: Vidale, Massimo
name: Olivieri, Luca Maria
name: Guida, Giuseppe
Publisher: name: Restauro Archeologico
Year: 2019

description: A series of samples taken from gilded Gandharan sculpted objects in schist (both portable artifacts and architectural decorative components), coming from different sacred sites of ancient Gandhara and the Swat valley, are in the course of analytical inspection. They are studied by the means of different archaeometric techniques. Although, given the precarious conservation and rarity of the objects available for analysis, our preliminar results cannot be generalized, the emerging evidence is discussed in the light of the gilding technologies so far described in other cultural areas and periods. It is also argued that, in the Gandharan cultual complexes, the surface of sacred images might be covered with diverging procedures, dictated by various technical and/or religious concerns.
description: Restauro Archeologico, Vol. 27 No. 1 (2019)
The Power to Change: A Brief Survey of the Wind Power’s Technological and Societal Potential, Barriers to Use, and Ways Forward
Creators: name: Kopnina, Helen
Publisher: name: Visions for Sustainability
Year: 2020

description: With the effects of climate change linked to the use of fossil fuels becoming more noticeable, political establishment and society appear ready for renewable energy. Yet, despite these expectations, fossil fuels still comprise nine-tenths of the global commercial energy supply. In this article, the history, technology, and barriers to acceptance of wind energy will be explored. The central question is why, despite the problems associated with the fossil fuels, more ecologically benign energy is still scarcely used. Having briefly surveyed some literature on the role of political and corporate stakeholders, as well as theories relating to factors responsible for the grassroots’ resistance (“not in my backyard” or NIMBYs) to renewable energy, the findings indicate that motivation for opposition to wind power varies. While the grassroots resistance is often fueled by the mistrust of the government, the governments’ reason for resisting renewable energy can be explained by their history of a close relationship with the industrial partners. This article develops an argument that understanding of various motivations for resistance at different stakeholder levels and understanding the role of democracy in decision-making opens up space for better strategies for a successful energy transition.
description: Visions for Sustainability, New Visions (2020)
Crystal structure studies and antimicrobial activities of transition metal complexes of pyridine-2,6-dicarboxylic acid and imidazole containing water clusters
Creators: name: G. Y. S. K. Swamy
name: P. Sivanarayanan
name: B. Sridhar
name: Laxmikanth Rao Joshi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Two new copper(II) and chromium(III) complexes of tridentate 2,6-pyridinedicarboxylic acid (H2pydc) with imidazole (im), (Him)[Cu(Hpydc)(pydc)]∙H2pydc∙5H2O (1) and (Him)[Cr(pydc)2]∙H2pydc∙5H2O (2), have been prepared and characterized by elemental analysis, TGA measurements, FT-IR, and UV–Vis spectroscopy, powder and single crystal X-ray crystallography. Crystal structure analyses reveal that both copper(II) and chromium(III) ions are in a distorted octahedral environment. The optimized geometrical parameters were calculated using methods based on the density functional theory (DFT). These calculations agree closely with the X-ray structure. The antimicrobial activities of the ligand and the complexes were evaluated in vitro and compared with drugs in use. The results show that the complexes had stronger antibacterial activity than the corresponding ligand and the effectiveness was confirmed against Bacillus subtilis (gram positive) and Klebsiella pneumoniae (gram negative) for 1, and Escherichia coli and K. pneumoniae (gram negative) for 2 by the well diffusion method.
Sodium Ion Conductivity in Superionic IL-Impregnated Metal-Organic Frameworks: Enhancing Stability Through Structural Disorder.
Creators: name: Nozari, Vahid
name: Calahoo, Courtney
name: Tuffnell, Joshua M
name: Adelhelm, Philipp
name: Wondraczek, Katrin
name: Dutton, Siân E
name: Bennett, Thomas D
name: Wondraczek, Lothar
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Metal-organic frameworks (MOFs) are intriguing host materials in composite electrolytes due to their ability for tailoring host-guest interactions by chemical tuning of the MOF backbone. Here, we introduce particularly high sodium ion conductivity into the zeolitic imidazolate framework ZIF-8 by impregnation with the sodium-salt-containing ionic liquid (IL) (Na0.1EMIM0.9)TFSI. We demonstrate an ionic conductivity exceeding 2 × 10-4 S · cm-1 at room temperature, with an activation energy as low as 0.26 eV, i.e., the highest reported performance for room temperature Na+-related ion conduction in MOF-based composite electrolytes to date. Partial amorphization of the ZIF-backbone by ball-milling results in significant enhancement of the composite stability towards exposure to ambient conditions, up to 20 days. While the introduction of network disorder decelerates IL exudation and interactions with ambient contaminants, the ion conductivity is only marginally affected, decreasing with decreasing crystallinity but still maintaining superionic behavior. This highlights the general importance of 3D networks of interconnected pores for efficient ion conduction in MOF/IL blends, whereas pore symmetry is a less stringent condition.
A Hierarchy of Deaths: Stem Cells, Animals and Humans Understood by Developmental Biologists.
Creators: name: Merleau-Ponty, Noémie
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Human
Animal
Life
Death
developmental biology
Stem Cells

description: Stem cell basic science has sparked a lot of attention because of its use of cells coming from 'destroyed' embryos. An ethnographic study conducted in two developmental biology laboratories located in India and France demonstrates that lab professionals do not see the use of these cells as controversial. What appears to be a major topic of reflection is the killing of mice. A hierarchy of deaths is delineated when biologists evoke the kind of lives at play in their science. A comparison between narrations of cell experimentations and mice sacrifices enriches a biological approach to the living through genetics, which is nonetheless performed in daily scientific practices. Laboratory workers enact other perceptions that point at being alive or having a life. They acknowledge, with personal convictions or expressions of intense affects, lives that are said to be embodied and experienced, while being hierarchised for the sake of science and dying patients. Laboratory workers' narratives of a hierarchy of deaths provide them with arguments to engage with discussions happening outside of their workplace about the handling of living materials in experimental settings.
Crystal structure studies and antimicrobial activities of transition metal complexes of pyridine-2,6-dicarboxylic acid and imidazole containing water clusters
Creators: name: G.Y.S.K. Swamy
name: P. Sivanarayanan
name: B. Sridhar
name: Laxmikanth Rao Joshi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Two new copper(II) and chromium(III) complexes of tridentate 2,6-pyridine dicarboxylic acid (H2pydc) with imidazole (im), (Him)[Cu(Hpydc)(pydc)]∙H2pydc∙5H2O (1) and (Him)[Cr(pydc)2]∙H2pydc∙5H2O (2), have been prepared and characterized by elemental analysis, TGA measurements, FT-IR and UV-vis spectroscopy, powder and single crystal X-ray crystallography. Crystal structure analyses reveal that both copper(II) and chromium(III) ions are in a distorted octahedral environment. The optimized geometrical parameters were calculated using methods based on the density functional theory (DFT). These calculations agree closely with the X-ray structure. The antimicrobial activities of the ligand and the complexes were evaluated in vitro and compared with drugs in use. The results show that the complexes had stronger antibacterial activity than the corresponding ligand and the effectiveness was confirmed against B. subtilis (gram positive) and K. pneumoniae (gram negative) for 1, and E.coli and K. pneumoniae (gram negative) for 2 by the well diffusion method.
Population structure and antimicrobial resistance patterns of Salmonella Typhi isolates in urban Dhaka, Bangladesh from 2004 to 2016.
Creators: name: Rahman, Sadia Isfat Ara
name: Dyson, Zoe A
name: Klemm, Elizabeth J
name: Khanam, Farhana
name: Holt, Kathryn E
name: Chowdhury, Emran Kabir
name: Dougan, Gordon
name: Qadri, Firdausi
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: BACKGROUND:Multi-drug resistant typhoid fever remains an enormous public health threat in low and middle-income countries. However, we still lack a detailed understanding of the epidemiology and genomics of S. Typhi in many regions. Here we have undertaken a detailed genomic analysis of typhoid in urban Dhaka, Bangladesh to unravel the population structure and antimicrobial resistance patterns in S. Typhi isolated between 2004-2016. PRINCIPAL FINDINGS:Whole genome sequencing of 202 S. Typhi isolates obtained from three study locations in urban Dhaka revealed a diverse range of S. Typhi genotypes and AMR profiles. The bacterial population within Dhaka were relatively homogenous with little stratification between different healthcare facilities or age groups. We also observed evidence of exchange of Bangladeshi genotypes with neighboring South Asian countries (India, Pakistan and Nepal) suggesting these are circulating throughout the region. This analysis revealed a decline in H58 (genotype 4.3.1) isolates from 2011 onwards, coinciding with a rise in a diverse range of non-H58 genotypes and a simultaneous rise in isolates with reduced susceptibility to fluoroquinolones, potentially reflecting a change in treatment practices. We identified a novel S. Typhi genotype, subclade 3.3.2 (previously defined only to clade level, 3.3), which formed two localized clusters (3.3.2.Bd1 and 3.3.2.Bd2) associated with different mutations in the Quinolone Resistance Determining Region (QRDR) of gene gyrA. SIGNIFICANCE:Our analysis of S. Typhi isolates from urban Dhaka, Bangladesh isolated over a twelve year period identified a diverse range of AMR profiles and genotypes. The observed increase in non-H58 genotypes associated with reduced fluoroquinolone susceptibility may reflect a change in treatment practice in this region and highlights the importance of continued molecular surveillance to monitor the ongoing evolution of AMR in Dhaka. We have defined new genotypes and lineages of Bangladeshi S. Typhi which will facilitate the identification of these emerging AMR clones in future surveillance efforts.
Managing Harmful Algae Blooms in Worcester
Creators: name: Caffrey, Daniel
name: Galvez, Diana
name: Liang, Zheng
name: Pesce, Austin
Publisher: name: QUBES Educational Resources
Year: 2025

description: The City of Worcester has multiple different bodies of water accessible to the community for recreational purposes. Every summer, residents from all over the city like to visit the different recreational areas to make the most out of the hot summer weather. However, most people are not aware of the implications of Harmful Algal Bloom (HABs) formation. This kind of HAB can cause many adverse health effects in both humans and animals including vomiting, diarrhea and flu-like symptoms. HAB formation has been an issue identified from a local to an international level. Many places and organizations have established a set of guidelines to manage the potential effects that HABs could cause. In order to manage recreational water quality and avoid closing beaches, a management strategy that covers prevention, monitoring, treatment and response strategies should be established. We collaborated with Worcester’s Department of Public Works (DPW) to recommend management strategies for prevention, monitoring, treatment and response for HABs in Worcester. Worcester's current strategies are more developed when compared to other locations. After compiling our research, we came to the conclusion that Worcester is ahead of the curve judging on their implementation of methods for each category under prevention, monitoring & testing, treatment, and response. However, after conducting extensive research, interviews and literature reviews, we found several methods that can be augmented or implemented to Worcester’s current efforts to manage HABs. In the other hand, we believe that Worcester’s current treatment methods are working fine for the city and preventing HAB formation is only another way we can keep the lakes safe. Therefore, asides from Aluminum sulfate, prevention is the second best treatment. Lastly, for the response, we determined that most locations perform the same basic actions when it comes to public notification of harmful algal blooms; the three main methods to do this are posting of signs at the affected waterbody, posts on websites, and posts on social media.
Educação em Ciências com Orientação CTS: Revisão de estudos no Ensino Básico em Portugal
Creators: name: Oliveira, Joana
name: Vieira, Rui Marques
Publisher: name: Indagatio Didactica
Year: 2019

description: Um dos principais desafios da sociedade atual passa por uma educação de todos os cidadãos que os torne capazes de intervir de forma crítica, fundamentada e responsável na resolução de problemas do dia a dia e de participar no mundo em constante mudança. Para esse efeito, alguns investigadores têm alertado para a importância e para a necessidade de uma Educação em Ciências desde os primeiros anos, norteada pela orientação Ciência-Tecnologia- Sociedade (CTS). Esta proposta perspetiva uma visão holística das ciências e privilegia, entre outras, as questões do quotidiano. Neste contexto, surgiu uma investigação do tipo integrativo realizada a 20 estudos sobre a qual recai o presente artigo. Para que fosse possível cumprir a finalidade de sintetizar e definir o status atual da investigação, a nível nacional, no âmbito da Educação em Ciências com orientação CTS, foi feita uma pesquisa minuciosa nos repositórios de algumas Instituições de Ensino Superior de Portugal. Dessa pesquisa resultaram alguns estudos que foram analisados criteriosamente e que permitiram criar um corpus documental onde estão compiladas estratégias e recursos didáticos passíveis de serem implementados em sala de aula. Apesar do ainda reduzido número de investigações nesta área, é claramente percetível a unanimidade entre todas elas no que se refere à importância da orientação CTS no Ensino das Ciências por, entre outros, privilegiar um ensino contextualizado.
description: Indagatio Didactica, vol. 11 n.º 2 (2019)
On the Birch and Swinnerton-Dyer conjecture and ERG Theory
Creators: name: Wright, Nicholas R.
Publisher: name: figshare
Year: 2018
Subjects: subject: 10301 Numerical Analysis
subject: FOS: Mathematics

description: We prove the integrality and modularity of the Birch and Swinnerton-Dyer conjecture with ERG Theory. Inspection of the conjecture shows that it is a phenomenological model. Thus, a solution could be found through regression analysis. Numerical verification is possible through nominative determinism/visibility theory. By adding adaptive learning (AL) to the model, the model admits an important time variation in beliefs, which would be ruled out under rational expectations. Entropy can be given from a detailed molecular analysis of the system. In summary, perception consists of the selection, organization, and interpretation of stimuli. These factors affect the conduct of work. We include two inequalities on the log-volume change associated to appropriately chosen deformations.
In Focus: Understanding Depth of Field and Its Creative Applications
Creators: name: Oliveira D., M. Jorge
Publisher: name: Empowerverse Media & Communication Solutions Agency
Year: 2024
Subjects: depth of field
creative applications
photography

description: As photographers, we are constantly exploring ways to elevate our craft and capture compelling images. One fundamental aspect that plays a crucial role in shaping the aesthetics of our photos is depth of field. In this article, we will unravel the mysteries of depth of field and explore its creative applications in photography.
Frequency and Type of Conflicts of Interest in the Peer Review of Basic Biomedical Research Funding Applications: Self-Reporting Versus Manual Detection
Creators: name: Gallo, Stephen
Publisher: name: figshare
Year: 2016
Subjects: subject: 160599 Policy and Administration not elsewhere classified
subject: FOS: Political science

description: Despite the presumed frequency of conflicts of interest in scientific peer review, there is a paucity of data in the literature reporting on the frequency and type of conflicts that occur, particularly with regard to the peer review of basic science applications. To address this gap, the American Institute of Biological Sciences (AIBS) conducted a retrospective analysis of conflict of interest data from the peer review of 282 biomedical research applications via several onsite review panels. The overall conflicted-ness of these panels was significantly lower than that reported for regulatory review. In addition, the majority of identified conflicts were institutional or collaborative in nature. No direct financial conflicts were identified, although this is likely due to the relatively basic science nature of the research. It was also found that 65 % of identified conflicts were manually detected by AIBS staff searching reviewer CVs and application documents, with the remaining 35 % resulting from self-reporting. The lack of self-reporting may be in part attributed to a lack of perceived risk of the conflict. This result indicates that many potential conflicts go unreported in peer review, underscoring the importance of improving detection methods and standardizing the reporting of reviewer and applicant conflict of interest information. *- The final publication is available at link.springer.com (http://link.springer.com/article/10.1007%2Fs11948-015-9631-7)
Variatie in schooltijden. Een internationale literatuurstudie naar de effecten van verschillende invullingen van de schooldag, de schoolweek en het schooljaar.
Creators: name: Driessen, Geert
name: Claassen, Adrie
name: Smit, Frederik
Publisher: name: Radboud University, Nijmegen, The Netherlands
Year: 2010
Subjects: schooltijden

description: De hoeveelheid tijd die kinderen aan onderwijs-, opvang- en vrijetijdsactiviteitenbesteden en de verdeling daarvan over de dag, de week en het jaar vormen al langonderwerp van discussie. Variatie in de inrichting en invulling van de tijd heeft gevolgenvoor de uiteenlopende betrokkenen, niet alleen voor de kinderen zelf, maarook voor hun ouders en de instellingen voor onderwijs, opvang en vrijetijdsbestedingen de professionals en vrijwilligers die daar werkzaam zijn. Recentelijk is er sprakevan een aantal ontwikkelingen op dit terrein. Gewezen kan worden op de groeiendearbeidsparticipatie van vrouwen, de toegenomen vraag naar opvang, veranderingen inwet- en regelgeving, en de hoge vlucht die brede scholen hebben genomen. Er isechter nog niet zoveel bekend over wat nu de precieze effecten zijn van al die verschillendevarianten van tijdsbestedingen. En wat er bekend is, is bovendien vaak nietgebaseerd op wetenschappelijk onderzoek en alleen in versnipperde vorm beschikbaar.Om die reden heeft het ministerie van OCW het ITS van de Radboud UniversiteitNijmegen verzocht hier een reviewstudie naar te verrichten. Het doel daarvan wasom zicht te krijgen op de effecten van de variatie in de besteding van tijd aan onderwijs,opvang en vrije tijd op de verschillende betrokkenen. Centraal stonden kinderenin de basisschoolleeftijd in Nederland, België (Vlaanderen), Frankrijk, Engeland,Zweden, Noorwegen en de Verenigde Staten. De onderzoeksperiode had betrekkingop de jaren vanaf 1990. Het accent lag op evaluatieve studies waarin op wetenschappelijkewijze en volgens gangbare methodologisch standaarden effecten van variatiesin tijden waren bepaald.
Establishment of a standard reference material (SRM) herbal DNA barcode library of Vitex negundo L. (lagundi) for quality control measures
Creators: name: Olivar, Jay Edneil C.
name: Joanner Paulus Erik P. Alaba
name: Atienza, Jose Francisco M.
name: Jerick Jeffrey S. Tan
name: Maximo T. Umali IV
name: Grecebio Jonathan D. Alejandro
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Plant Biology

description: The majority of the population in the Philippines relies on herbal products as their primary source for their healthcare needs. After the recognition of Vitex negundo L. (lagundi) as an important and effective alternative medicine for cough, sore throat, asthma and fever by the Philippine Department of Health (DOH), there was an increase in the production of lagundi-based herbal products in the form of teas, capsules and syrups. The efficiency of these products is greatly reliant on the use of authentic plant material, and to this day no standard protocol has been established to authenticate plant materials. DNA barcoding offers a quick and reliable species authentication tool, but its application to plant material has been less successful due to (1) lack of a standard DNA barcoding loci in plants and (2) poor DNA yield from powderised plant products. This study reports the successful application of DNA barcoding in the authentication of five V. negundo herbal products sold in the Philippines. Also, the first standard reference material (SRM) herbal library for the recognition of authentic V. negundo samples was established using 42 gene accessions of ITS, psbA-trnH and matK barcoding loci. Authentication of the herbal products utilised the SRM following the BLASTn and maximum-likelihood (ML) tree construction criterion. Barcode sequences were retrieved for ITS and psbA-trnH of all products tested and the results of the study revealed that only one out of five herbal products satisfied both BLASTn and ML criterion and was considered to contain authentic V. negundo. The results prompt the urgent need to utilise DNA barcoding in authenticating herbal products available in the Philippine market. Authentication of these products will secure consumer health by preventing the negative effects of adulteration, substitution and contamination.
Giuris aporocephalus
Creators: name: Keith, Philippe
name: Mennesson, Marion I.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Perciformes
Eleotridae
Giuris
Giuris aporocephalus

description: Giuris aporocephalus (Macleay, 1884)
(Figs 1, 5, 10; Tabs III-IV)
description: Published as part of Keith, Philippe & Mennesson, Marion I., 2020, Review of Giuris (Teleostei: Eleotridae) from Indo-Pacific islands, with description of three new species, pp. 331-349 in Cybium 44 (4) on page 343, DOI: 10.26028/cybium/2020-444-004, http://zenodo.org/record/12711981
The Numerus Clausus Law of 1920: Asymmetrical Dependencies, and the “Twisted Road” of Hungarian Jews to Auschwitz
Creators: name: Bodó, Béla
Publisher: name: Bonn Center for Dependency and Slavery Studies
Year: 2022
Subjects: subject: Dependency and Slavery Studies
subject: Hungarian Jews
subject: Antisemitism
subject: Interwar Period
subject: Shoah
subject: Holocaust
subject: Assimilation
subject: Numerus Clausus Law
subject: ddc:940

description: This working paper examines the impact of the infamous numerus clausus legislation of 1920, which limited the share of Jewish students at institutions of higher learning to their proportion of the population, on incoming students, the position of Jewish graduates in the labor market, and the changing status of Jews in Hungary in the interwar period. It argues that the law not only reversed the process of Jewish emancipation in Hungary, but it also paved the way for the rise of a new form of relationship characterized by strong asymmetrical dependence, between the Hungarian elite and middle classes and their Jewish counterparts in the interwar period. The essay focuses on agency, the elimination of "exit strategies", social marginalization, and the fate of university graduates during the Shoah.