Ethiopian Field Epidemiology Training Program (EFETP) Compiled Body of Works in Field Epidemiology
Creators: name: Awoke, Sisay
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2017

description: Introduction Measles is an acute, highly contagious viral disease caused by measles virus and transmitted primarily by respiratory droplets or airborne spray to mucous membranes in the upper respiratory tract or the conjunctiva. Globally during 2002–2009, 180,284 suspected measles cases were reported, of these, 97,204 (54%) were discarded because of a negative or indeterminate measles specific IgM test result; 10,071 (14%) had unknown classification; and 73,009 (41%) were confirmed as measles. Among 2,190 suspected measles cases reported in 61 separate outbreaks in Ethiopia (2015), of which 929 cases were confirmed positive. The aim of this study was to investigate the outbreak and identify associated factors for measles outbreak and to take possible intervention measures in Basso Liben district. Methods and materials We conducted 1: 2 unmatched case control studies. Face to face interview was conducted to gathered information from cases and controls by using structured questionnaire. Sample size was calculated using Stat calc function of Epi-info version 7 with confidence level of 95%, power of 80%, and assuming percent of controls exposed 18% and percent of cases with exposure 52% for un-vaccination. Total sample size included in the study was 30 cases and 60 controls. Before conducting interview informed verbal consent was obtained from all study participants to meet ethical standards. We entered data to Epi info version 7 and analyzed it by using SPSSversion20 software; finally the model was fitted by using multivariate logistic regression with 95% confidence level and p-value &lt;0.05. Results In Basso Liben district the total attack rate of measles was 1.24 per 1000 population. The highest age specific attack rate was in under- one age groups (4.76 per 1000 children), and the next was in age groups 1-4 years old which was 3.28 per 1000 population. In multivariate logistic regression contact history with measles case AOR=8.132 (95% CI 2.047, 32.297) and presence of measles case in the neighbour AOR= 6.928 (95% CI 1.37, 29.12) were risk factors for contracting measles. Sisay Awoke, sisaya16@gmail.com,Ethiopian Field Epidemiology Training Programme Sisay Awoke, sisaya16@gmail.com, Ethiopian Field Epidemiology Training Programme Page 14 But previous history of measles case AOR= 0.10 (95% CI 0.02, 0.56) and vaccinated with measles vaccine AOR=0.11(95%CI 0.021, 0.573) were protective associated factors for measles. Conclusion In multivariate logistic analysis presences of measles case in the neighbour and contact with measles case were significant associated factors for contracting measles, but previous history of being measles case and vaccination were protective factors for measles. Basso Liben district health office and health centers should improve and strength routine measles vaccine immunization coverage and also under- 30 years age groups should be targeted for supplementary immunization programme for measles. Key words; measles, outbreak, Basso Liben, case control, Ethiopia