cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2 of Development and validation of a pre- and intra-operative scoring system that distinguishes between non-advanced and advanced axillary lymph node metastasis in breast cancer with positive sentinel lymph nodes: a retrospective study
Creators: name: Murata, Takeshi
name: Watase, Chikashi
name: Shiino, Sho
name: Kurita, Arisa
name: Ogawa, Ayumi
name: Jimbo, Kenjiro
name: Iwamoto, Eriko
name: Yoshida, Masayuki
name: Takayama, Shin
name: Suto, Akihiko
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Hematology

description: Additional file 2: Table S1. Evaluation of multivariable collinearity with P < 0.1 in the univariate analysis. Table S2. Distribution of advanced ALNM (pN2-N3) stratified by the total score in the training and validation cohorts in patients with one or two metastatic SLNs. Table S3. Predictive ability of the scoring system to differentiate between non-advanced and advanced ALNM at each cutoff point in the training cohort (A) and validation cohort (B) in patients with one or two metastatic sentinel lymph nodes.
Supplementary methods and discussion from Ageing effects of social environments in "non-social" insects
Creators: name: Harrison, Lauren Maree
name: Churchill, Emily R
name: Fairweather, Megan
name: Smithson, Claire H
name: Chapman, Tracey
name: Bretman, Amanda
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified

description: Phil-Trans-Review_SUPPLEMENTARY.docx
УНИВЕРСИТЕТСКИЙ РЕЙТИНГ RAEX-100 В 2012-2022 Г.Г.: СТАТИСТИЧЕСКИЙ ПОРТРЕТ РОССИЙСКИХ ВУЗОВ
Creators: name: Тараканов А.В.
Publisher: name: Образование и право
Year: 2022
Subjects: университетский рейтинг
статус университета
профиль деятельности
позиции в рейтинге
численность студентов
обеспеченность преподавателями
тренды
корреляционная матрица

description: В статье анализируется состав топ-25 отечественного рейтинга RAEX-100, объединяющего 100 сильнейших вузов России. Рассматриваются статус, профиль деятельности университетов, а также их основные характеристики: численность студентов, обеспеченность учебного процесса преподавательскими кадрами и др. Представлен анализ временных рядов для позиций, занимавшихся участниками топ-25 за все годы существования рейтинга. На основании данных временных рядов получены уравнения трендов, позволяющие прогнозировать изменения в составе группы сильнейших в краткосрочной перспективе. С помощью корреляционной матрицы проведен анализ влияния основных характеристик университетов на их положение в рейтинге. Подтверждено соответствие основных закономерностей формирования списка «лучших из лучших» для отечественного и ведущих мировых рейтингов.
ФОРМИРОВАНИЕ РОССИИ КАК СОЦИАЛЬНОГО ГОСУДАРСТВА
Creators: name: Виноградова Е.В.
Publisher: name: Образование и право
Year: 2022
Subjects: идентичность
социальное государство
российская государственность.

description: Формирование России как социального государства происходит на протяжении всей ее истории. В статье анализируется отечественный опыт социальных проектов. Анализ правовых актов, принимаемых на протяжении многих столетий, позволил прийти к выводу о том, что социальная ответственность власти в России имеет глубокие исторические корни.
Additional file 1 of Investigation of the relationship between geomagnetic activity and solar wind parameters based on a novel neural network (potential learning)
Creators: name: Kitajima, Ryozo
name: Nowada, Motoharu
name: Kamimura, Ryotaro
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1: Table S1. Values of all four measures (accuracy, precision, recall, and F-measure), their averages and numbers of true positives, false positives, true negatives, and false negatives in 10 patterns (models) at r = 5 and all equations to the four measures are summarized.
ЦИФРОВОЕ РАЗВИТИЕ ПРОМЫШЛЕННОГО ОБЕСПЕЧЕНИЯ В УСЛОВИЯХ ПАТЕНТНЫХ САНКЦИЙ
Creators: name: Самогин А.С.
Publisher: name: Образование и право
Year: 2022
Subjects: цифровое развитие
промышленное обеспечение
патентные санкции
интеллектуальная собственность
правовое регулирование
Россия.

description: В статье анализируются сложности на отечественном рынке программного обеспечения в условиях патентных санкций государств Запада. Предлагаются меры для поддержания цифрового развития промышленного обеспечения Российской Федерации. Констатируется необходимость выработки действенных механизмов противодействия такого рода санкционному режиму с целью снижения зарубежного давления на отечественную экономику.
Computational Design of a PAK1 Binding Protein
Creators: name: Butterfoss, Glenn L.
name: Kuhlman, Brian
name: Jha, Ramesh K.
name: Szyperski, Thomas
name: Wu, Yibing
name: Leaver-Fay, Andrew
name: Yin, Shuangye
name: Dokholyan, Nikolay V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: We describe a computational protocol, called DDMI, for redesigning scaffold proteins to bind to a specified region on a target protein. The DDMI protocol is implemented within the Rosetta molecular modeling program and uses rigid-body docking, sequence design, and gradient-based minimization of backbone and side chain torsion angles to design low energy interfaces between the scaffold and target protein. Iterative rounds of sequence design and conformational optimization were needed to produce models that have calculated binding energies that are similar to binding energies calculated for native complexes. We also show that additional conformation sampling with molecular dynamics can be iterated with sequence design to further lower the computed energy of the designed complexes. To experimentally test the DDMI protocol we redesigned the human hyperplastic discs protein to bind to the kinase domain of p21-activated kinase 1 (PAK1). Six designs were experimentally characterized. Two of the designs aggregated and were not characterized further. Of the remaining four designs, three bound to the PAK1 with affinities tighter than 350 μM. The tightest binding design, named Spider Roll, bound with an affinity of 100 μM. NMR –based structure prediction of Spider Roll based on backbone and 13Cβ chemical shifts using the program CS-ROSETTA indicated that the architecture of human hyperplastic discs protein is preserved. Mutagenesis studies confirmed that Spider Roll binds the target patch on PAK1. Additionally, Spider Roll binds to full length PAK1 in its activated state, but does not bind PAK1 when it forms an auto-inhibited conformation that blocks the Spider Roll target site. Subsequent NMR characterization of the binding of Spider Roll to PAK1 revealed a comparably small binding `on-rate' constant (<< 105 M−1 s−1). The ability to rationally design the site of novel protein-protein interactions is an important step towards creating new proteins that are useful as therapeutics or molecular probes.
Hyperbolic manifolds with a large number of systoles
Creators: name: Dória, Cayo
name: Freire, Emanoel M. S.
name: Murillo, Plinio G. P.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Geometric Topology (math.GT)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: Primary 53C22, 11F06

description: In this article, for any $n\geq 4$ we construct a sequence of compact hyperbolic $n$-manifolds $\{M_i\}$ with number of systoles at least as $\mathrm{vol}(M_i)^{1+\frac{1}{3n(n+1)}-ε}$ for any $ε>0$. In dimension 3, the bound is improved to $\mathrm{vol}(M_i)^{\frac{4}{3}-ε}$. These results generalize previous work of Schmutz for $n=2$, and Dória-Murillo for $n=3$ to higher dimensions.
description: minor changes to include referee suggestions
First-Dose Pharmacokinetics of Lithium Carbonate in Children and Adolescents
Creators: name: Findling, Robert L.
name: Kowatch, Robert
name: Landersdorfer, Cornelia B.
name: Pavuluri, Mani
name: McClellan, Jon
name: Lingler, Jacqui
name: McNamara, Nora K.
name: Jusko, William J.
name: Kafantaris, Vivian
name: Sikich, Linmarie
name: Taylor-Zapata, Perdita
name: Faber, Jon
name: Frazier, Jean A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Bipolar I disorder (BP-I) in children and adolescents is associated with substantive psychosocial dysfunction and human suffering [1, 2]. Safe and effective treatments are needed to reduce symptomatology and improve quality of life for the vulnerable youngsters and families impacted by this illness. Lithium is a benchmark treatment for adults suffering from bipolar illness [3], with evidence of benefit dating back almost 60 years [4]. However, there has been relatively little research regarding the use of lithium in the treatment of youths suffering from mania [5]. Given this paucity of information, a Written Request (WR) was issued by the Food and Drug Administration (FDA) under the auspices of the Best Pharmaceuticals for Children Act (BPCA) (FDA 2002) for the study of this agent in youths. In response, a contract was awarded to rigorously study lithium in children and adolescents with mania. A key step in developing evidence-based dosing paradigms for any compound is the characterization of the drug s pharmacokinetics (PK) [6]. Therefore, two of the goals of this contract were to characterize the pharmacokinetics of lithium and to develop evidence-based dosing for lithium in children and adolescents [7]. Although many studies have examined the PK of lithium in adults [8a??10], relatively little is known about the PK of lithium in pediatric patients. Vitiello et al. [11] described lithium PK in nine children (aged 9a??12 years) with a DSM-III-R primary diagnosis of conduct disorder or adjustment disorder. Subjects received one single 300 mg dose of lithium carbonate. The disposition of lithium in these children appeared to generally be similar to that seen in adults. However, their elimination half-life and greater total lithium clearance were shorter than reported in adult studies. The present study was performed in order to describe the first dose PK of lithium in children and adolescents. In addition to characterizing the disposition of lithium in children and adolescents with BP-I, we also explored whether patient-specific characteristics (e.g. age, gender and weight) influence the PK of lithium in this patient population.
Additional file 1 of The realities and expectations of community involvement in COVID-19 research: a Consumer Reference Group perspective
Creators: name: Adams, Claire
name: Albert, Paul
name: Benson, Tim
name: Cordingley, Anne
name: Daniels, Barbara
name: Fynn, Noreen
name: Gurgone, Mary
name: Jeffery, Chris
name: White, Ann
name: Strobel, Natalie
Publisher: name: figshare
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 1: Inforgraphics developed for dissemination.
ЭКЗАМЕН ПО СТАНДАРТАМ ВОРЛДСКИЛЛС КАК ФОРМА ИТОГОВОЙ АТТЕСТАЦИИ ПО ПРОГРАММАМ СПО
Creators: name: Чупина И.П.
name: Зырянова Н.И.
name: Чучкалова Е.И.
name: Маскина О.Г.
Publisher: name: Образование и право
Year: 2022
Subjects: демонстрационный экзамен
социальное партнерство
профессиональные организации
кадровый потенциал
востребованные специальности
мировые стандарты
передовые технологии
работодатели.

description: Данная тема актуальна в настоящее время, так как новые форматы итоговой аттестации студентов СПО с 2017 года входят активно в образовательный процесс. Это видно из содержания статьи, где приведены цифры сдачи демонстрационного экзамена по годам. Данная тема получила научную разработанность в трудах российских и зарубежных ученых, но пока на незначительном уровне. Цель данной статьи заключается в изучении проведения форматов демонстрационного экзамена по стандартам WorldSkills. Задачами статьи являются изучение достоинств и недостатков проведения новой формы итоговой аттестации в формате демонстрационного экзамена. Рассмотрены проблемы образовательных организаций СПО на соответствие материальной базы при проведении демонстрационного экзамена. Показаны трудности организаций СПО по оборудованию специальной сертифицированной площадки, где оборудование должно в точности соответствовать утвержденному перечню. В статье использован статистический метод для показа данных по проведению демонстрационного экзамена, начиная с 2017 года по 2022 год. Метод аналогии использован при сравнении проведения итоговой аттестации традиционным способом и проведении демонстрационного анализа. Метод сравнительного анализа показывает, что каждая образовательная организация выбирает способ проведения итоговой аттестации, основываясь на своих ресурсах и финансовых возможностях. Результатами статьи являются исследования авторов по проблемам и перспективам проведения демонстрационного экзамена. В заключении говорится о том, что для современной экономики необходимы новые подходы к образовательной системе и оценка ее результатов.
Increasing Sequence Diversity with Flexible Backbone Protein Design: The Complete Redesign of a Protein Hydrophobic Core
Creators: name: Murphy, Grant S.
name: Machius, Mischa
name: Mills, Jeffrey L.
name: Szyperski, Thomas
name: Miley, Michael J.
name: Kuhlman, Brian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Protein design tests our understanding of protein stability and structure. Successful design methods should allow the exploration of sequence space not found in nature. However, when redesigning naturally occurring protein structures most fixed backbone design algorithms return amino acid sequences that share strong sequence identity with wild-type sequences, especially in the protein core. This behavior places a restriction on functional space that can be explored and is not consistent with observations from nature, where sequences of low identity have similar structures. Here, we allow backbone flexibility during design to mutate every position in the core (38 residues) of a four-helix bundle protein. Only small perturbations to the backbone, 1-2 Å, were needed to entirely mutate the core. The redesigned protein, DRNN, is exceptionally stable (melting point > 140 °C). An NMR and X-ray crystal structure show that the side chains and backbone were accurately modeled (all-atom RMSD = 1.3 Å).
Additional file 1 of Job insecurity and mental health related outcomes among the humanitarian workers during COVID-19 pandemic: a cross-sectional study
Creators: name: Sultana, Naznin
name: Asaduzzaman, Md.
name: Siddique, Abu Bakkar
name: Khatun, Hafeza
name: Bari, Farzana Sultana
name: Islam, Md. Nazrul
name: Tabassum, Arifa
name: Mondol, Abdus Salam
name: Sayem, Md. Abu
name: Abdullah, Abu Yousuf Md
name: Hossain, M. Pear
name: Biracyaza, Emmanuel
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Table S1. Determinants of job insecurity among the humanitarian worker. Table S2. Determinants of depression among the humanitarian worker using ordinal logistic regression. Table S3. Determinants of anxiety among the Humanitarian Worker using ordinal logistic regression. Table S4. Determinants of stress among the Humanitarian Worker using ordinal logistic regression.
A few remarks on the theory of non-nilpotent graphs
Creators: name: Żak, Radosław
Publisher: name: arXiv
Year: 2022
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics

description: We prove a few results about non-nilpotent graphs of symmetric groups $S_n$ -- namely that they have a Hamiltonian cycle and they satisfy a conjecture of Nongsiang and Saikia. The latter is likewise proven for alternating groups $A_n$. We also show that the class of non-nilpotent graphs does not have any ''local'' properties, ie. for every simple graph $X$ there is a group $G$, such that its non-nilpotent graph has $X$ as an induced subgraph.
Dirac Fermions in Blue-Phosphorus
Creators: name: Li, Yuanchang
name: Chen, Xiaobin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We propose that Dirac cones can be engineered in phosphorene with fourfold-coordinated phosphorus atom. The key is to separate in energy the in-plane ($s$, $p_x$ and $p_y$) and out-of-plane ($p_z$) oribtals through the $sp^2$ configuration, yielding respective $σ$- and $π$-character Dirac cones, and then quench the latter. As a proof-of-principle study, we realize $σ$-character Dirac cone in hydrogenated/fluorinated phosphorene with the honeycomb lattice. The obtained Dirac cones are at $K$-points, slightly anisotropic, with Fermi velocities of 0.91/1.23 times that of graphene along $Γ$K/KM direction, and maintain a good linearity up to $\sim$2 eV for holes. One substantive advantage of $σ$-character Dirac cone is its convenience to tune the Dirac gap via in-plane strain. Our findings pave a new way for development of high performance electronic devices based on Dirac materials.
description: accepted by 2D Materials
Comparison of Data Representations and Machine Learning Architectures for User Identification on Arbitrary Motion Sequences
Creators: name: Schell, Christian
name: Hotho, Andreas
name: Latoschik, Marc Erich
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Reliable and robust user identification and authentication are important and often necessary requirements for many digital services. It becomes paramount in social virtual reality (VR) to ensure trust, specifically in digital encounters with lifelike realistic-looking avatars as faithful replications of real persons. Recent research has shown that the movements of users in extended reality (XR) systems carry user-specific information and can thus be used to verify their identities. This article compares three different potential encodings of the motion data from head and hands (scene-relative, body-relative, and body-relative velocities), and the performances of five different machine learning architectures (random forest, multi-layer perceptron, fully recurrent neural network, long-short term memory, gated recurrent unit). We use the publicly available dataset "Talking with Hands" and publish all code to allow reproducibility and to provide baselines for future work. After hyperparameter optimization, the combination of a long-short term memory architecture and body-relative data outperformed competing combinations: the model correctly identifies any of the 34 subjects with an accuracy of 100% within 150 seconds. Altogether, our approach provides an effective foundation for behaviometric-based identification and authentication to guide researchers and practitioners. Data and code are published under https://go.uniwue.de/58w1r.
description: in press at IEEE VRAI 2022
Mind the Labels: Describing Relations in Knowledge Graphs With Pretrained Models
Creators: name: Kasner, Zdeněk
name: Konstas, Ioannis
name: Dušek, Ondřej
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences
subject: I.2.7

description: Pretrained language models (PLMs) for data-to-text (D2T) generation can use human-readable data labels such as column headings, keys, or relation names to generalize to out-of-domain examples. However, the models are well-known in producing semantically inaccurate outputs if these labels are ambiguous or incomplete, which is often the case in D2T datasets. In this paper, we expose this issue on the task of descibing a relation between two entities. For our experiments, we collect a novel dataset for verbalizing a diverse set of 1,522 unique relations from three large-scale knowledge graphs (Wikidata, DBPedia, YAGO). We find that although PLMs for D2T generation expectedly fail on unclear cases, models trained with a large variety of relation labels are surprisingly robust in verbalizing novel, unseen relations. We argue that using data with a diverse set of clear and meaningful labels is key to training D2T generation systems capable of generalizing to novel domains.
description: Long paper at EACL '23. Code and data: https://github.com/kasnerz/rel2text
Tasks Structure from Comparing Self-Other Distinction Across Motor, Cognitive, and Affective Domains
Creators: name: Pronizius, Ekaterina
name: Bukowski, Henryk
name: Lamm, Claus
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 529999
subject: Other psychology not elsewhere classified

description: Pronizius_SOD5_SM.pdf
АКТУАЛИЗАЦИЯ МЕР ВОСПИТАТЕЛЬНОЙ РАБОТЫ, НАПРАВЛЕННОЙ НА СОБЛЮДЕНИЕ ЗАКОННОСТИ СОТРУДНИКАМИ ПОЛИЦИИ
Creators: name: Криводерева Д.Ю.
Publisher: name: Образование и право
Year: 2022
Subjects: воспитательная работа
служебная деятельность
законность
правопорядок
нарушение законности
служебная дисциплина
сотрудник полиции.

description: В статье рассматривается проблематика реализуемых мер воспитательного характера, по средствам которых обеспечивается соблюдение законности и дисциплины сотрудниками полиции. Тенденция актуальности данной темы ежегодно возрастает, что указывает на необходимость разрешения ряда проблемных вопросов, связанных с организацией деятельности сотрудников полиции. В настоящее время вопрос соблюдения законности и дисциплины достаточно остро стоит перед всей системой Министерства внутренних дел. Это отражается как в количестве совершенных сотрудниками полиции правонарушений и преступлений, так и в значительном числе неукомплектованных должностей. Выявленный ряд недостатков и многочисленных фактов нарушения законности сотрудниками органов внутренних дел, оставляет негативный отпечаток на всей системе и порождает недоверие народа к правоохранительным органам. Таким образом, в статье рассматривается необходимость выработки более подходящей формы административно-правового и воспитательного воздействия на сотрудников полиции для минимизации факторов, приводящих к нарушению законности и дисциплины. При рассмотрении вопроса действенности мер административно-правового механизма в данной статье используются общенаучные методы исследования, такие как: системный, аналитический, классификационный, а также юридические методы: сравнительно-правовой, формально-юридический и другие.
Towards natural inflation from weakly coupled heterotic string theory
Creators: name: Abe, Hiroyuki
name: Kobayashi, Tatsuo
name: Otsuka, Hajime
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose the natural inflation from the heterotic string theory on "Swiss-Cheese" Calabi-Yau manifold with multiple $U(1)$ magnetic fluxes. Such multiple $U(1)$ magnetic fluxes stabilize the same number of the linear combination of the universal axion and Kähler axions and one of the Kähler axions is identified as the inflaton. This axion decay constant can be determined by the size of one-loop corrections to the gauge kinetic function of the hidden gauge groups, which leads effectively to the trans-Planckian axion decay constant consistent with the WMAP, Planck and/or BICEP2 data. During the inflation, the real parts of the moduli are also stabilized by employing the nature of the "Swiss-Cheese" Calabi-Yau manifold.
description: 22 pages
Additional file 1 of Prognostic and predictive biomarkers for response to neoadjuvant chemoradiation in esophageal adenocarcinoma
Creators: name: Matani, Hirsch
name: Sahu, Divya
name: Paskewicz, Michael
name: Gorbunova, Anastasia
name: Omstead, Ashten N.
name: Wegner, Rodney
name: Finley, Gene G.
name: Jobe, Blair A.
name: Kelly, Ronan J.
name: Zaidi, Ali H.
name: Goel, Ajay
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Additional file 1.
ВЗАИМООТНОШЕНИЯ ГОСУДАРСТВА И ЛИЧНОСТИ В ФИЛОСОФСКО-ПРАВОВОМ ОСМЫСЛЕНИИ
Creators: name: Агамиров К.В.
Publisher: name: Образование и право
Year: 2022
Subjects: государство
личность
социализм
постиндустриальное общество
индустрия знаний
правовая система
право
свобода
закон
социальный консенсус.

description: В статье исследуются предикаты социального взаимодействия публичной власти и личности. В историческом ключе устанавливаются составляющие социалистического правовопорядка, целеуказатели правомерного поведения, соразмерные условия их материализации и профилактики социальных отклонений. Наряду с соблюдением публичной властью советского периода основных прав человека, защитой права на труд и ликвидацией безработицы, наличием бесплатной медицины, бесплатного образования и минимума материальной обеспеченности, социалистическая система со временем изжила себя. Значительно более высокий уровень жизни в капиталистических странах обеспечивался конкуренцией в условиях запрещенной в СССР частной собственности и сопутствующим ей изобилием товаров народного потребления. Сегодняшнее постиндустриальное общество – это доминирование высоких информационных технологий, способствующих формированию высокоразвитой экономики, индустрии знаний, повышению уровня и качества жизни. В то же время оно породило новые противоречия между государством и личностью, связанные с большим разрывом доходов различных социальных групп. Автор анализирует отмеченные составляющие взаимодействия публичной власти и гражданина в правовом и философском аспектах и приходит к выводу о том, что снятие социальной напряженности возможно на основе долговременной коммуникации по линии основополагающих прав и свобод человека и гражданина вне зависимости от возраста и социальной принадлежности, осуществление которых сделает осуществимым достижение политического и правового консенсусов публичной власти и личности.
БИОМЕТРИЧЕСКИЕ ТЕХНОЛОГИИ В ФИНТЕХ: ПРАКТИКА И ПЕРСПЕКТИВЫ
Creators: name: Зарубин М.Ю.
Publisher: name: Образование и право
Year: 2022
Subjects: финтех
финансовые технологии
биометрические технологии
идентификация
аутентификация.

description: В статье рассмотрена российская и международная практика внедрения биометрических технологий в финансовой сфере. Проанализированы результаты проектов по внедрению биометрических технологий. Цель исследования заключается в формировании основных тенденций дальнейшего развитию применения биометрии в финансовой сфере. Были сделаны выводы о том, что система биометрии может стать некой превентивной мерой для совершения злоумышленниками преступлений, направленных на кражу персональных данных. Однако для этого необходимо совершенствование действующего законодательство, формирование методических основ для регулирования этой сферы, а также формирования систем кибербезопасности.
ВОПРОСУ О СУЩНОСТИ БАНКРОТСТВА И ЕГО ХАРАКТЕРИСТИКАХ
Creators: name: Майстренко А.Г.
name: Майстренко Г.А.
Publisher: name: Образование и право
Year: 2022
Subjects: предпринимательств кая деятельность
банкротство
несостоятельность
экономическая система государства
кредиторы
форс-мажор
индивидуальные предприниматели
корпорации
недостаточность средств.

description: Развитие экономической системы любого современного государства предполагает поддержку перспективных, социально значимых предпринимательских проектов, и одним из направлений такой поддержки выступает взвешенный подход к организации и проведению процедур банкротства. В статье отражен авторский взгляд на банкротство, его причины и основные характеристики, объективная оценка которых может сыграть значимую роль в определении разумной стратегии процедур банкротства, их индивидуализации сообразно сложившейся ситуации.
Quantum repeater via entangled phase modulated multimode coherent states
Creators: name: Goncharov, Roman
name: Kiselev, Alexei D.
name: Kiselev, Fedor
name: Moiseev, Eugene S.
name: Samsonov, Eduard
name: Moiseev, Sergei A.
name: Egorov, Vladimir
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a scheme of quantum repeater that uses entangled multimode coherent states which are obtained by electro-optic modulation of symmetric and antisymmetric Schrödinger cat states. In this method subcarrier modes of the phase modulated states generated by the remote parties are sent to a symmetric beam splitter at the central node. The entangled coherent states are heraldedly prepared by photon counting measurements at the output channels of the beam splitter. We study how the effects of decoherence in the quantum channel affect statistics of photocounts and corresponding fidelity. We show how the proposed scheme can be useful for extending range of quantum key distribution with sub carrier wave encoding by exploiting quantum teleportation with the generated entanglement.
description: 18 pages, 10 figures
Gold on WSe2 Single Crystal Film as a Substrate for Surface Enhanced Raman Scattering (SERS) Sensing
Creators: name: Mukherjee, Bablu
name: Leong, Wei Sun
name: Li, Yida
name: Gong, Hao
name: Sun, Linfeng
name: Shen, Ze Xiang
name: Simsek, Ergun
name: Thong, John T. L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Synthesis and characterization of high-quality single-crystal WSe2 films on highly-insulating substrate is presented. We demonstrate for the first time that the presence of gold nanoparticles in the basal plane of a WSe2 film can enhance its Raman scattering intensity. The experimentally observed enhancement ratio in the Raman signal correlates well with the simulated electric field intensity using a three-dimensional electromagnetic software and theoretical calculation. This work provides guidelines for the use of two-dimensional WSe2 films as a SERS substrate.
Report of the 2011-2012 AACP Special Advisory Committee on Research and Graduate Education
Creators: name: Nahata, Milap
name: Crismon, Lynn
name: Brixner, Diana
name: Wu-Pong, Susanna
name: Torchilin, Vladimir P.
name: Lau (Convener), Yuen-Sum (Vincent)
name: Sorkness, Christine
name: Jusko, William
name: Cutler, Stephen
name: Blouin, Robert
name: Ho, Rodney
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: According to the Bylaws of the American Association of Colleges of Pharmacy (AACP), the Research and Graduate Affairs Committee (RGAC) shall provide assistance to the Association in developing its research, graduate education, and scholarship agenda. This assistance may include facilitating colleges and schools in formulating and advancing legislative and regulatory initiatives, and nurturing collaborative activities with organizations sharing an interest in issues related to the pharmaceutical sciences.
ВОПРОСЫ ЦИФРОВИЗАЦИИ И ИНФОРМАЦИОННОЙ БЕЗОПАСНОСТИ
Creators: name: Грудцына Л.Ю.
name: Миронов А.Л.
Publisher: name: Образование и право
Year: 2022
Subjects: цифровая экономика
цифровые права
правовая защита
интеллектуальная собственность
коллективное управление правами
база данных
производительность труда.

description: В статье автор исследует некоторые актуальные в настоящее время вопросы цифровой экономики, цифровых прав и информационной безопасности (на примере финансовых рисков). С проникновением технологий во все сферы жизни, в том числе, и социальной, а также в связи с неизбежным процессом цифровизации в мире, появились цифровые права. В статье автор делает вывод о том, что цифровизация или цифровая экономика представляет собой хозяйственную деятельность, основой функционирования и развития которой являются цифровые технологии. Инновация цифровизации все больше проникает в повседневную жизнь людей. Она не только ускоряет процесс обмена информацией, но и повышает производительность труда.
The Prolyl Isomerase Pin1 Targets Stem-Loop Binding Protein (SLBP) To Dissociate the SLBP-Histone mRNA Complex Linking Histone mRNA Decay with SLBP Ubiquitination
Creators: name: Minderman, H.
name: Fritz, A.
name: Krishnan, N.
name: Berezney, R.
name: Thapar, R.
name: Rempinski, D.
name: Lam, T. T.
name: Marzluff, W. F.
name: O'Loughlin, K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Histone mRNAs are rapidly degraded at the end of S phase, and a 26-nucleotide stem-loop in the 3′ untranslated region is a key determinant of histone mRNA stability. This sequence is the binding site for stem-loop binding protein (SLBP), which helps to recruit components of the RNA degradation machinery to the histone mRNA 3′ end. SLBP is the only protein whose expression is cell cycle regulated during S phase and whose degradation is temporally correlated with histone mRNA degradation. Here we report that chemical inhibition of the prolyl isomerase Pin1 or downregulation of Pin1 by small interfering RNA (siRNA) increases the mRNA stability of all five core histone mRNAs and the stability of SLBP. Pin1 regulates SLBP polyubiquitination via the Ser20/Ser23 phosphodegron in the N terminus. siRNA knockdown of Pin1 results in accumulation of SLBP in the nucleus. We show that Pin1 can act along with protein phosphatase 2A (PP2A) in vitro to dephosphorylate a phosphothreonine in a conserved TPNK sequence in the SLBP RNA binding domain, thereby dissociating SLBP from the histone mRNA hairpin. Our data suggest that Pin1 and PP2A act to coordinate the degradation of SLBP by the ubiquitin proteasome system and the exosome-mediated degradation of the histone mRNA by regulating complex dissociation.
Evaluation of in-channel amperometric detection using a dual-channel microchip electrophoresis device and a two-electrode potentiostat for reverse polarity separations: Microfluidics and Miniaturization
Creators: name: Lunte, Susan M.
name: Pichetsurnthorn, Pann
name: da Silva, José A. F.
name: Gunasekara, Dulan B.
name: de Abreu, Fabiane C.
name: Meneses, Diogenes
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: In-channel amperometric detection combined with dual-channel microchip electrophoresis is evaluated using a two-electrode isolated potentiostat for reverse polarity separations. The device consists of two separate channels with the working and reference electrodes placed at identical positions relative to the end of the channel, enabling noise subtraction. In previous reports of this configuration, normal polarity and a three-electrode detection system were used. In the two-electrode detection system described here, the electrode in the reference channel acts as both the counter and reference. The effect of electrode placement in the channels on noise and detector response was investigated using nitrite, tyrosine, and hydrogen peroxide as model compounds. The effects of electrode material and size and type of reference electrode on noise and the potential shift of hydrodynamic voltammograms for the model compounds were determined. In addition, the performance of two- and three-electrode configurations using Pt and Ag/AgCl reference electrodes was compared. Although the signal was attenuated with the Pt reference, the noise was also significantly reduced. It was found that lower LOD were obtained for all three compounds with the dual-channel configuration compared to single-channel, in-channel detection. The dual-channel method was then used for the detection of nitrite in a dermal microdialysis sample obtained from a sheep following nitroglycerin administration.
Noise-induced multistability in chemical systems: Discrete vs Continuum modeling
Creators: name: Duncan, Andrew
name: Liao, Shuohao
name: Vejchodsky, Tomas
name: Erban, Radek
name: Grima, Ramon
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: Subcellular Processes (q-bio.SC)
subject: FOS: Biological sciences

description: The noisy dynamics of chemical systems is commonly studied using either the chemical master equation (CME) or the chemical Fokker-Planck equation (CFPE). The latter is a continuum approximation of the discrete CME approach. We here show that the CFPE may fail to capture the CME's prediction of noise-induced multistability. In particular we find a simple chemical system for which the CME's marginal probability distribution changes from unimodal to multimodal as the system-size decreases below a critical value, while the CFPE's marginal probability distribution is unimodal for all physically meaningful system sizes.
description: 5 pages, 2 figures
Academic Self-concept in Black Adolescents: Do Race and Gender Stereotypes Matter?
Creators: name: Kurtz-Costes, Beth
name: Copping, Kristine E.
name: Evans, Ashley B.
name: Rowley, Stephanie J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: We examined the relation between race- and gender-group competence ratings and academic self-concept in 252 Black seventh- and eighth-graders. On average, youth reported traditional race stereotypes, whereas gender stereotypes were traditional about verbal abilities and were nontraditional regarding math/science abilities. Among boys, in-group gender and in-group race-based competence ratings (i.e. ratings of boys and Blacks) were related to math/science and verbal self-concepts. However, only gender-based ratings (i.e. ratings of girls’ abilities for reading/writing) were related to girls’ self-concepts. These findings suggest that the influence of race stereotypes on Black adolescents’ academic self-concepts is different for girls than boys. Whereas self-relevant gender groups were associated with both Black girls’ and boys’ academic self-concept, race-based competence ratings were only relevant for the academic self-views of Black boys.
Landfill gas upgrading using amine-functionalized silica sorbents
Creators: name: Johnson, Olusola
name: Gopalakrishnan, Umadevi
name: Joseph, Babu
name: Kuhn, John N.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Neuroscience
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine

description: Separation of acid gases such as CO2 from biogas is a key step for its purification before biomethane is used in various applications such as injection into a pipeline or use as a vehicle fuel. In this study, the single step purification of real biogas (locally collected landfill gas) was demonstrated using (3-Aminopropyl) triethoxysilane (APTES)-grafted SBA-15. The sorbent was optimized between amine amount and accessibility to adsorption sites. In studies using a surrogate mixture of CH4/CO2 the sorbent recorded an adsorption capacity of 0.85 mmolCO2/gads under dry conditions and this decreased to 0.72 mmolCO2/gads when the surrogate biogas was saturated with steam. Even though the capacity was further decreased to 0.55 mmolCO2/gads using real landfill gas, it remained fairly stable over 5 cycles despite the presence of impurities, namely hydrogen sulfide (68 ppm). In all cases, the capacity was regenerated with a thermal treatment in inert gas at 100°C. The results suggested possibilities for a single step purification unit to remove acid gasses and water and provide potential for a streamlined operation for the separation of carbon dioxide from biogas. The enhanced economics should propel the move toward a green energy future.
Modelling the effect of aerosol and greenhouse gas forcing on the South and East Asian monsoons with an intermediate complexity climate model
Creators: name: Recchia, Lucy
name: Lucarini, Valerio
Publisher: name: arXiv
Year: 2022
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Computational Physics (physics.comp-ph)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: The South and East Asian summer monsoons are globally significant meteorological features, creating a strongly seasonal pattern of precipitation. The stability of the monsoon is of extreme importance for a vast range of ecosystems and for the livelihoods of a large share of the world's population. Simulations are performed with an intermediate complexity climate model, PLASIM, to assess the future response of the monsoons to changing concentrations of aerosols and greenhouse gases. The aerosol loading consists of a mid-tropospheric warming and a surface cooling, which is applied to India, Southeast Asia and East China, both concurrently and independently. The primary effect of increased aerosol loading is a decrease in summer precipitation in the vicinity of the applied forcing, although the regional response varies significantly. The decrease in precipitation is only partially ascribable to a decrease in the precipitable water, and instead derives from a reduction of the precipitation efficiency, due to changes in the stratification of the atmosphere. When the aerosol loading is added in all regions simultaneously, precipitation in East China is most strongly affected, with a quite distinct transition to a low precipitation regime as the radiative forcing increases beyond 60 W/m^2. The response is less abrupt as we move westward, with precipitation in South India being least affected. This lower sensitivity in South India is attributed to aerosol forcing over East China. Additionally, the effect on precipitation is approximately linear with the forcing. The impact of doubling carbon dioxide levels is to increase precipitation over the regions and weaken the circulation. When the carbon dioxide and aerosol forcings are applied at the same time, the carbon dioxide forcing partially offsets the surface cooling and reduction in precipitation associated with the aerosol response.
description: 37 pages, 14 figures plus 12 Supplementary figures
ИЗ КОЛОНИАЛЬНОЙ ИСТОРИИ РОД-АЙЛЕНДА: ПРОБЛЕМЫ ИДЕОЛОГИИ, ПОЛИТИКИ И ПРАВА
Creators: name: Тимонин М.А.
Publisher: name: Образование и право
Year: 2022
Subjects: английская колония
колониальная идеология
соглашение
общественный договор
усеченная демократия.

description: Этатизация и демократизация колониальной Америки на примере Род-Айленда – актуальная задача отечественной юриспруденции. Поскольку решение данной задачи осложняется некритическим восприятием отдельными отечественными авторами зарубежных историко-теоретических конструктов, то налицо необходимость нового её разрешения. Цели: раскрыть идейно-теоретические и политико-правовые аспекты колониальной истории Род-Айленда; выявить и критически рассмотреть основные точки зрения, имеющиеся в научной литературе, по данной проблематике; установить реальный политико-правовой статус этой колонии. Методы: исторический, логический, сравнительно-правовой, формально-догматический. Результаты: Род-Айленд был задуман как полная антитеза Массачусетсу в своем отношении к духовной свободе, индейцам, политическому и правовому режиму Бостона и даже метрополии. Но реалии колониальной жизни вынудили руководство этого новообразования к систематическому отступлению от первоначальных замыслов. Неполнота и противоречивость их реализации стали характерными приметами всех сфер жизнедеятельности этой колонии. В духовной жизни идея превосходства «белого человека», религиозный сепаратизм причудливым образом сочетались с идеями гуманизма, конституционализма, равноправия, народного суверенитета и полной веротерпимости. Несмотря на очевидную несовместимость отдельных идейно-теоретических конструктов, колонисты были едины в своем исключении из «политического тела» колонии индейцев, афроамериканцев и даже белых кабальных слуг, в отрицании их гражданских прав. Заключение: изложенное свидетельствует против научной традиции, в соответствие с которой завышаются уровень демократизации Род-Айленда и степень его автономии от метрополии. Вплоть до завершения войны за независимость он оставался новообразованием, переходным к государству.
Additional file 1 of Early administration of hydrocortisone, vitamin C, and thiamine in adult patients with septic shock: a randomized controlled clinical trial
Creators: name: Lyu, Qing-Quan
name: Zheng, Rui-Qiang
name: Chen, Qi-Hong
name: Yu, Jiang-Quan
name: Shao, Jun
name: Gu, Xiao-Hua
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1: Table S1. Worst–Best/Best–Worst case analyses of the primary outcome. Table S2. Worst-possible/best-possible case analyses of the 72-h SOFA score. Table S3. Cox multivariate analysis of factors influencing 90-day mortality in patients. Fig. S1. Subgroup analysis of 90-day mortality. The forest map shows the grouped factors of the subgroup analysis, HR for 90-day mortality, 95% CI in each subgroup, and P value for interaction of treatment (intervention or placebo) and the factor. There were no significant interactions in any of the subgroups (P > 0.1 for all comparisons).
ИЗУЧЕНИЕ ПРОБЛЕМ СОЦИАЛЬНО-ПРАВОВОГО РОССИЙСКОГО ГОСУДАРСТВА В УЧЕБНОМ КУРСЕ «ОСНОВЫ И ПРИНЦИПЫ РОССИЙСКОЙ ГОСУДАРСТВЕННОСТИ»
Creators: name: Сальников В.П.
name: Захарцев С.И.
name: Воронков К.И.
Publisher: name: Образование и право
Year: 2022
Subjects: Российская государственность
алгоритм обучения
ДНК России
высшее образование
наука.

description: Обосновывается настоятельная необходимость в закреплении определенных тем социально-правового российского государства в разрабатываемом учебном курсе «Основы и принципы российской государственности». Предполагается, что предложение о включении проблемных аспектов социального и правового отечественного государства в создаваемый учебный курс обогатит теоретический материал и позволит студентам расширить представление о российской государственности. Поставленные проблемы анализируются в связи с происходящей трансформацией современного Российского государства и общества.
Self-views of African-American Youth are Related to the Gender Stereotypes and Ability Attributions of Their Parents
Creators: name: Kizzie Rouland, Karmen
name: Johnson Rowley, Stephanie
name: Kurtz-Costes, Beth
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: We examined relations among African American mothers’ (N = 392) stereotypes about gender differences in mathematics, science, and reading performance, parents’ attributions about their children’s academic successes and failures, and their seventh and eighth grade children’s academic self-views (domain-specific ability attributions and self-concept). Parents’ stereotypes about gender differences in abilities were related to their ability attributions for their children’s successes and failures within academic domains. Mothers’ attributions, in turn, were related to children’s attributions, particularly among girls. Mothers’ attributions of their children’s successes to domain-specific ability were related to the self-concepts of daughters, and failure attributions were related to domain-specific self-concepts of sons. The influences of parents’ beliefs on young adolescents’ identity beliefs are discussed.