cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
SKI and SMAD4 are essential for IL-21-induced Th17 differentiation
Creators: name: Wan, Yisong Y.
name: Zhang, Ge
name: Zhang, Song
Publisher: name: Elsevier
Year: 2019

description: Th17 cells are essential for the pathogenesis of inflammatory and autoimmune diseases. In the presence of TGF-β, the differentiation of Th17 cells can be induced by inflammatory cytokines, especially IL-6, which is mainly produced by antigen presenting cells (APCs); or IL-21, which is derived from T cells. IL-21 is required for IL-6-induced Th17 cell differentiation. However, the key regulators and underlying mechanisms for IL-21-induced Th17 differentiation is still elusive. Here we show that SMAD4 is a key regulator in IL-21-induced Th17 differentiation. SMAD4 deficient naïve T cells can differentiate into Th17 cells in the absence of TGF-β signaling, and these Th17 cells are pathogenic during EAE. SMAD4 represses Rorc mRNA transcription to constrain IL-21-induced Th17 differentiation in the absence of TGF-β signaling. While in the presence of TGF-β, SMAD4 losses its suppressive ability due to the degradation of SKI. Mutation of Y429A or A432E on SMAD4 disrupts the interaction of SKI from SMAD4 and eliminates SMAD4 mediated suppression of Th17 differentiation. SMAD4 is indispensable for SKI binding to Rorc promoter region to regulate Th17 differentiation. Moreover, activin can induce Th17 differentiation in combination with IL-21, and the process is also subjected to the control of SKI and SMAD4. This study therefore elucidates critical mechanism for IL-21-induced Th17 differentiation to indicate SKI and SMAD4 as potential therapeutic targets for treating autoimmune diseases.
SKI Expression Suppresses Pathogenic Th17 Cell Response and Mitigates Experimental Autoimmune Encephalomyelitis
Creators: name: Li, Ping
name: Guo, Zengli
name: Wan, Yisong Y.
Publisher: name: Frontiers
Year: 2021

description: Pathogenic Th17 cells are critically involved in many autoimmune diseases, while non-pathogenic Th17 cells are more immune regulatory. Understanding the mechanisms of the induction and maintenance of pathogenic Th17 cells will benefit the development of therapeutic treatments of related diseases. We have shown that the transforming growth factor-β (TGFβ) induced SKI degradation and dissociation from Smad4 complex is a prerequisite for TGFβ-induced Th17 cell differentiation. However, it is unclear whether and how SKI regulates pathogenic Th17 differentiation, which does not require TGFβ cytokine. Here we showed that SKI expression was downregulated during pathogenic Th17 cell differentiation and the ectopic expression of SKI abrogated the differentiation of pathogenic Th17 cells. Functionally, using a knock-in mouse model, we found ectopic SKI expression specifically in T cells prevented myelin oligodendrocyte glycoprotein peptide (MOG33–55) induced experimental autoimmune encephalomyelitis (EAE), an animal model of human multiple sclerosis. We further revealed that induced SKI expression in already differentiated pathogenic Th17 cells reduced the maintenance of Th17 program and ameliorated EAE in an adoptive T cell transfer model. Therefore, our study provides valuable insights of targeting SKI to modulate pathogenic Th17 cell function and treat Th17-related diseases.
Dynamics of a Mechanical System with Multiple Degrees of Freedom out of Thermal Equilibrium
Creators: name: Feigel, A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Out of thermal equilibrium, an environment imposes effective mechanical forces on microscopical nanofabricated devices, chemical or biological systems. Here we address the question of how to calculate these forces together with the response of the system from the first principles. We show that an ideal gas-like environment, even near thermal equilibrium, can enforce a specific steady state on the system by creating effective potentials in otherwise homogeneous space. An example of stable and unstable rectifications of thermal fluctuations is presented using modified Feynman-Smoluchowski ratchet with two degrees of freedom. Moreover, the stability of a steady configuration depends on its chiral symmetry. The transition rate probabilities and the corresponding kinetic equations are derived for a complex mechanical system with arbitrary degrees of freedom. This work therefore extends the applicability of mechanical systems as a toy model playground of statistical physics for multiple degrees of freedom active and living matter.
Spatial-Temporal Dependency Modeling and Network Hub Detection for Functional MRI Analysis via Convolutional-Recurrent Network
Creators: name: Liu, Mingxia
name: Shen, Dinggang
name: Zhang, Daoqiang
name: Yao, Dongren
name: Lian, Chunfeng
name: Wang, Mingliang
Publisher: name: Institute of Electrical and Electronics Engineers (IEEE)
Year: 2019

description: Early identification of dementia at the stage of mild cognitive impairment (MCI) is crucial for timely diagnosis and intervention of Alzheimer's disease (AD). Although several pioneering studies have been devoted to automated AD diagnosis based on resting-state functional magnetic resonance imaging (rs-fMRI), their performance is somewhat limited due to non-effective mining of spatial-temporal dependency. Besides, few of these existing approaches consider the explicit detection and modeling of discriminative brain regions (i.e., network hubs) that are sensitive to AD progression. In this paper, we propose a unique Spatial-Temporal convolutional-recurrent neural Network (STNet) for automated prediction of AD progression and network hub detection from rs-fMRI time series. Our STNet incorporates the spatial-temporal information mining and AD-related hub detection into an end-to-end deep learning model. Specifically, we first partition rs-fMRI time series into a sequence of overlapping sliding windows. A sequence of convolutional components are then designed to capture the local-to-global spatially-dependent patterns within each sliding window, based on which we are able to identify discriminative hubs and characterize their unique contributions to disease diagnosis. A recurrent component with long short-term memory (LSTM) units is further employed to model the whole-brain temporal dependency from the spatially-dependent pattern sequences, thus capturing the temporal dynamics along time. We evaluate the proposed method on 174 subjects with 563 rs-fMRI scans from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database, with results suggesting the effectiveness of our method in both tasks of disease progression prediction and AD-related hub detection.
Technisches Feedback System verbessert Händehygiene und reduziert durch MRE verursachte nosokomiale Infektionen
Creators: name: Braß, Patrick
name: Alefelder, Christof
Publisher: name: Robert Koch-Institut
Year: 2020
Subjects: subject: Hygiene
subject: Desinfektionsmittel
subject: Prävention
subject: Händehygiene
subject: nosokomiale Erkrankung
subject: 610 Medizin und Gesundheit

description: In Deutschland liegt die Prävalenz nosokomialer Infektionen (NI) auf Intensivstationen bei 15–20 %. NI gehen mit einer deutlich erhöhten Letalität einher, verlängern die Krankenhausverweildauer und verursachen zusätzliche Kosten. Die Mehrzahl der NI wird durch die Hände der Mitarbeitenden übertragen. Eine der wirksamsten Maßnahmen zur Unterbrechung von Infektionsketten in Gesundheitseinrichtungen und damit zur Prävention von NI ist die hygienische Händedesinfektion. Obwohl dies bekannt ist, ist die Compliance insgesamt gering und die Ausführung oft insuffizient. Im vorliegenden Bericht wird über die Erfahrungen mit der Einführung eines technischen Unterstützungssystems zur Verbesserung der Händehygiene berichtet.
Nonequilibrium dynamics in the one-dimensional Fermi-Hubbard model: A comparison of the nonequilibrium Green functions approach and the density matrix renormalization group method
Creators: name: Schluenzen, N.
name: Joost, J. -P.
name: Heidrich-Meisner, F.
name: Bonitz, M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The nonequilibrium dynamics of strongly-correlated fermions in lattice systems have attracted considerable interest in the condensed matter and ultracold atomic-gas communities. While experiments have made remarkable progress in recent years, there remains a need for the further development of theoretical tools that can account for both the nonequilibrium conditions and strong correlations. For instance, time-dependent theoretical quantum approaches based on the density matrix renormalization group (DMRG) methods have been primarily applied to one-dimensional setups. Recently, two-dimensional quantum simulations of the expansion of fermions based on nonequilibrium Green functions (NEGF) have been presented [Schluenzen et al., Phys. Rev. B 93, 035107 (2016)] that showed excellent agreement with the experiments. Here we present an extensive comparison of the NEGF approach to numerically accurate DMRG results. The results indicate that NEGF are a reliable theoretical tool for weak to intermediate coupling strengths in arbitrary dimensions and make long simulations possible. This is complementary to DMRG simulations which are particularly efficient at strong coupling.
title: ADCO, Privilèges de l'Ordre de Cîteaux en matière de succession (Fin XVe siècle), Cart. 176 (11 H 8), f. 0097
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Privilèges de l'Ordre de Cîteaux en matière de succession (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 176 (11 H 8), f. 0097, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Privilèges de l'Ordre de Cîteaux en matière de succession (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 176 (11 H 8), f. 0097, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Additional file 3: of Molecular characterization of larval development from fertilization to metamorphosis in a reef-building coral
Creators: name: Strader, Marie
name: Aglyamova, Galina
name: Matz, Mikhail
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Histogram of mean counts (after removal of lowly expressed genes). Mean expression values for candidate genes egfZPm (8.62) and RFP (11.91) are highlighted with arrows. (PDF 417Â kb)
Strategies for recruiting populations to participate in the chronic disease self-management program (CDSMP): A systematic review
Creators: name: Kneipp, Shawn M.
name: Horrell, Lindsey N.
Publisher: name: Taylor & Francis
Year: 2017

description: The purpose of this review was to better understand how to market the Chronic Disease Self-Management Program to new audiences. Eight databases were searched for peer-reviewed studies of the CDSMP. A total of 39 articles were analyzed to describe the theoretical basis of recruitment strategies and their effectiveness while engaging diverse populations. Findings included that female, Caucasian, and elderly groups are overrepresented in CDSMP literature and recruitment efforts have not been explicitly grounded in theory. This review provides insight into trends in CDSMP recruitment and identifies the need for further research regarding the application of marketing theory to future enrollment efforts.
Reconfigurable defected microstrip phase shifter for phased array antennas
Creators: name: Ding, Can
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Beamforming and its most common variant, phased arrays, offer a number of advantages for wireless communications and radar systems. These include increased range and capacity, immunity against interference, and system flexibility. However, due to the associated high cost, both digital and analogue beamforming systems are primarily employed in defence and space applications where cost is not necessarily an obstacle. This thesis is motivated by a strong need from civilian applications where low-cost beamforming systems are required. In a beamforming system, a phase shifter is one of the most critical devices. Usually, a large number of phase shifters are employed, however they are very costly. Therefore, reducing the cost of phase shifters is an effective way to decrease the total cost of a beamforming system. And so, a phase shifter that is low in cost, compact, has an easy control method, and which can be constructed using a simple fabrication process is in high demand. In this thesis, firstly, some basics of phased arrays and different types of phase shifters used in phased arrays are reviewed. Then, a novel type of phase shifting unit called as reconfigurable defected microstrip structure (RDMS) is proposed. The RDMS is printed on a microstrip line due to its low cost, low complexity, and for its incomparable popularity in antenna and microwave designs. A series of phase shifters employing RDMS are discussed and integrated in phased arrays, to demonstrate their practicability in beamforming systems. Subsequently, a modified RDMS (MRDMS) phase-shifting unit is introduced, which is smaller in size but has comparable or even better performance. Based on the MRDMS unit, a complete phase shifter design scheme consisting of three steps is presented, and each step is elaborated with theory, simulation, and experiment. A significant improvement in performance and a reduction in cost are achieved and illustrated by comparing the performance of the phase shifters employing RDMS and MRDMS units to each other. Finally, the proposed RDMS- and MRDMS-based phase shifters are used to construct a phased array antenna and a reconfigurable PRS antenna, which proves them to be excellent candidates to provide phase shifts in antenna systems. Future work will focus on the realization of large-scale phased array antennas using the proposed phase shifters.
Latest trends in the study of accretion and outflows around compact objects
Creators: name: Chakrabarti, Sandip K.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Study of astrophysics of black holes and neutron stars has taken a new turn in the present decade with the realization that sub-Keplerian flows and the associated centrifugal barrier near the horizon or the surface of a neutron star play a major role in deciding the nature of the emitted spectra and the formation of outflows from the accreting matter. This region may remain steady or oscillate depending on the accretion rate, specific angular momentum and specific energy of the flow. Intricacies of oscillation may depend on the degree of feedback the inflow receives from the outflow. This region may emit hard or soft X-rays depending on relative numbers of hot elections and soft photons intercepted by this region. We discuss how these properties come about and how they explain the observational results of black hole candidates.
description: 13 pages 3 figures. arXiv admin note: text overlap with arXiv:astro-ph/0007259
Increasing-decreasing patterns in the iteration of an arithmetic function
Creators: name: Nathanson, Melvyn B.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11A25, 11B37, 11B83, 11D04, 68Q99

description: Let $Ω$ be a set of positive integers and let $f:Ω\rightarrow Ω$ be an arithmetic function. Let $V = (v_i)_{i=1}^n$ be a finite sequence of positive integers. An integer $m \in Ω$ has \textit{increasing-decreasing pattern} $V$ with respect to $f$ if, for all odd integers $i \in \{1,\ldots, n\}$, \[ f^{v_1+ \cdots + v_{i-1}}(m) < f^{v_1+ \cdots + v_{i-1}+1}(m) < \cdots < f^{v_1+ \cdots + v_{i-1}+v_{i}}(m) \] and, for all even integers $i \in \{2,\ldots, n\}$, \[ f^{v_1+ \cdots + v_{i-1}}(m) > f^{v_1+ \cdots +v_{i-1}+1}(m) > \cdots > f^{v_1+ \cdots +v_{i-1}+v_i}(m). \] The arithmetic function $f$ is \textit{wildly increasing-decreasing} if, for every finite sequence $V$ of positive integers, there exists an integer $m \in Ω$ such that $m$ has increasing-decreasing pattern $V$ with respect to $f$. This paper gives a proof that the Syracuse function is wildly increasing-decreasing.
description: 14 pages, improved and expanded
Datenmanagement im kommunalen Bildungsmonitoring: Ziele, Herausforderungen und Empfehlungen. Entwurf für die Fortbildung Datenmanagement
Creators: name: Förster, André
Publisher: name: Zenodo
Year: 2020
Subjects: Bildungsmonitoring
Datenmanagement
Transferinitiative
Transferagentur
DKBM
Kommunen

description: Präsentation des Entwurfs für die Fortbildung der Mitarbeiter der Transferagenturen zum Thema Datenmanagement im Rahmen des Konzeptgruppentreffens der Koordinierungsstelle Bildungsmonitoring am 22.01.2020 in Würzburg.
Probability distribution of the entanglement across a cut at an infinite-randomness fixed point
Creators: name: Devakul, Trithep
name: Majumdar, Satya N.
name: Huse, David A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We calculate the probability distribution of entanglement entropy S across a cut of a finite one dimensional spin chain of length L at an infinite randomness fixed point using Fisher's strong randomness renormalization group (RG). Using the random transverse-field Ising model as an example, the distribution is shown to take the form $p(S|L) \sim L^{-ψ(k)}$, where $k = S / \log [L/L_0]$, the large deviation function $ψ(k)$ is found explicitly, and $L_0$ is a nonuniversal microscopic length. We discuss the implications of such a distribution on numerical techniques that rely on entanglement, such as matrix product state (MPS) based techniques. Our results are verified with numerical RG simulations, as well as the actual entanglement entropy distribution for the random transverse-field Ising model which we calculate for large L via a mapping to Majorana fermions.
description: 6 pages, 4 figures
The source effect: development of a scale and assessment of the influence of self-esteem
Creators: name: Weston, Micheal
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: The source effect for disgust is the tendency for disgust elicitors emanating from unfamiliar others to elicit higher levels of disgust than those emanating from the self or close others (Case, Repacholi & Stevenson, 2006; Repacholi & Stevenson, 2005). Prior to this research, there was no distinct measure for the source effect. One of the reasons for this was the source effect has been compared to self-disgust which already has existing measurement tools. In Study 1 (N = 189), to demonstrate that the source effect is different to self-disgust, a valid and reliable measure of the source effect was developed and administered with measures of self-concept, self-disgust and disgust sensitivity. Findings indicate that self-disgust is more likened to an intense experience of shame as oppose to disgust. The source effect measure was revealed to be a reliable measure of the source effect, although it did not relate with disgust sensitivity, suggesting there are potentially other influential factors for the source effect. In Study 2 (N = 16), a behavioural measure of the source effect was implemented through a priming and stimulus engagement experiment. Participants were primed to a shame, anger or neutral condition and then were tested for the source effect towards disgust elicitors from the self and an unknown stranger. Preliminary findings suggest that shame may cause an individual to become more avoidant of their own disgust elicitors. Potential utility of the new measures and future research directions are discussed.
title: ADCO, Cartulaire des Dominicains de Dijon (1286), Cart. 221 (H 53), 170 folios, f. 0090
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire des Dominicains de Dijon (1286), Archives départementales de la Côte-d'Or, Cart. 221 (H 53), 170 folios. Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire des Dominicains de Dijon (1286), Archives départementales de la Côte-d'Or, Cart. 221 (H 53), 170 folios, f. 0090, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: Dijon
description: Provenance: http://www.wikidata.org/entity/Q7003
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb15250518p
description: Provenance: http://www.idref.fr/02643413X/id
description: Provenance: https://www.geonames.org/6453767
THE COMPLEXITIES OF GLOBAL CITIZENSHIP BEING MANAGED IN HIGHER EDUCATION
Creators: name: AKHILESH DALJEET BACCHOO
name: Dr. PRASHANT KUMAR MISHRA
Publisher: name: Zenodo
Year: 2025
Subjects: Global Citizenship Education (GCE), Higher Education Institutions (HEIs), Neoliberalism in Education, Equity and Inclusion, Decolonial Pedagogy.

description: Abstract

The pressures from globalization forces higher education institutions (HEIs) to develop graduates who demonstrably understand global responsibilities along with international values and ethical conduct. Academic institutions need to manage multiple aspects of global citizenship because they confront both theoretical and organizational obstacles. Global citizenship presents various definitions through its emphasis on cross-cultural skills and moral responsibility as well as critical worldwide understanding (Andreotti, 2006). To incorporate global citizenship into curricula and institutional missions universities need to find ways that resolve the conflicts between local needs and global potential (Rhoads & Szelenyi, 2011). The neoliberal shift in higher education creates obstacles since it reduces international engagement to market-oriented agenda while misleading students as global learners (Stein, 2017). The process of reducing global citizenship to employment-based skills functions in direct opposition to ethical development and civic engagement formation. The promotion of global citizenship faces challenges through barriers of access and equitable opportunities when teaching students from differing backgrounds especially in non-Western countries (Tikly, 2004). HEIs work to handle their complicated circumstances by implementing teaching advancements combined with international approaches and policy-making directions. The research uses current academic work to demonstrate why reflective practices with awareness about power structures should help students develop personal transformations and embrace multiple forms of global citizenship learning. Higher education remains essential for developing global citizens yet its fundamental purpose should be based on ethical thought and cultural awareness and social equality (Andreotti & de Souza, 2012).
Strategies to increase couples HIV testing and counselling in sub-Saharan Africa: a systematic review
Creators: name: Kasaro, Margaret
name: Mutale, Wilbroad
name: Chi, Benjamin H.
name: Saidi, Friday
name: Hampanda, Karen M.
name: Rosenberg, Nora E.
name: Jones, Katelyn R.
name: Graybill, Lauren A.
name: Pelowich, Krysta
name: Freeborn, Kellie
name: Kumwenda, Andrew
Publisher: name: Wiley
Year: 2023

description: INTRODUCTION: Couple HIV testing and counselling (CHTC) is associated with measurable benefits for HIV prevention and treatment. However, the uptake remains limited in much of sub-Saharan Africa, despite an expanded range of strategies designed to promote access. METHODS: Following PRIMSA guidelines, we conducted a systematic review to characterize CHTC uptake strategies. Five databases were searched. Full-text articles were included if they were: conducted in sub-Saharan Africa during the study period (1980-2019), targeted heterosexual couples, reported at least one strategy to promote CHTC and provided a quantifiable measure of CHTC uptake. After the initial and full-text screening, key features of the studies were abstracted and synthesized. RESULTS: Of the 6188 unique records found in our search, 365 underwent full-text review with 29 distinct studies included and synthesized. Most studies recruited couples through antenatal care (n = 11) or community venues (n = 8) and used provider-based HIV testing (n = 25). The primary demand creation strategies included home-based CHTC (n = 7); integration of CHTC into clinical settings (n = 4); distribution of HIV self-testing kits (n = 4); verbal or written invitations (n = 4); community recruiters (n = 3); partner tracing (n = 2); relationship counselling (n = 2); financial incentives (n = 1); group education with CHTC coupons (n = 1); and HIV testing at other community venues (n = 1). CHTC uptake ranged from negligible to nearly universal. DISCUSSION: We thematically categorized a diverse range of strategies with varying levels of intensity and resources used across sub-Saharan Africa to promote CHTC. Offering CHTC within couples' homes was the most common approach, followed by the integration of CHTC into clinical settings. Due to heterogeneity in study characteristics, we were unable to compare the effectiveness across studies, but several trends were observed, including the high prevalence of CHTC promotion strategies in antenatal settings and the promising effects of home-based CHTC, distribution of HIV self-tests and integration of CHTC into routine health services. Since 2019, an updated literature search found that combining partner notification and secondary distribution of HIV self-test kits may be an additionally effective CHTC strategy. CONCLUSIONS: There are many effective, feasible and scalable approaches to promote CHTC that should be considered by national programmes according to local needs, cultural context and available resources.
สภาวะที่เหมาะสมในการผลิตกรดอะซิติกโดยใช้กากตะกอนจากหลายแหล่งเพื่อใช้ในระบบกำจัดฟอสฟอรัสทางชีวภาพ
Creators: name: ฉัตรลดา เพียซ้าย
name: นิตยา บุญเทียน
name: อุษา ยิ่งชล
name: ธันชนก พรดอน
name: Padri, Mohamad
Publisher: name: กองบริหารการวิจัย
Year: 2563
Subjects: กรดอะซิติก
การหมัก
ตะกอนส่วนเกิน
ระยะเวลากักเก็บ

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 28, 2, 274-293
Misure RADAR Stazione Spaziale Internazionale (ISS) del settembre/ottobre 2019
Creators: name: ORTU, Pierluigi
name: Muntoni, Giacomo
name: Montisci, Giorgio
name: PISANU, Tonino
name: MAXIA, PAOLO
Publisher: name: O.A. Cagliari
Year: 2019

description: Il presente rapporto si prefigge l’obbiettivo di fornire una panoramica esaustiva sulle misure radar della stazione spaziale internazionale (ISS) effettuate dal gruppo di elettromagnetismo del DIEE in collaborazione con il personale dell’Osservatorio Astronomico di Cagliari (INAF-OAC). La campagna di misure si configura all’interno del progetto di ricerca DATA FUSION, riguardante la fusione dei dati provenienti da sensori ottici e radar per la determinazione orbitale di detriti spaziali. Gli echi radar della stazione spaziale sono stati ricevuti e registrati nelle date del 25-26 Settembre e del 2-11 Ottobre 2019. La configurazione radar utilizzata per osservare il passaggio della ISS è bi-statica, perciò costituita da una struttura trasmittente ed una ricevente.
Sub-Network Kernels for Measuring Similarity of Brain Connectivity Networks in Disease Diagnosis
Creators: name: Zhang, Daoqiang
name: Liu, Mingxia
name: Jie, Biao
name: Shen, Dinggang
Publisher: name: Institute of Electrical and Electronics Engineers (IEEE)
Year: 2018

description: As a simple representation of interactions among distributed brain regions, brain networks have been widely applied to automated diagnosis of brain diseases, such as Alzheimer's disease (AD) and its early stage, i.e., mild cognitive impairment (MCI). In brain network analysis, a challenging task is how to measure the similarity between a pair of networks. Although many graph kernels (i.e., kernels defined on graphs) have been proposed for measuring the topological similarity of a pair of brain networks, most of them are defined using general graphs, thus ignoring the uniqueness of each node in brain networks. That is, each node in a brain network denotes a particular brain region, which is a specific characteristics of brain networks. Accordingly, in this paper, we construct a novel sub-network kernel for measuring the similarity between a pair of brain networks and then apply it to brain disease classification. Different from current graph kernels, our proposed sub-network kernel not only takes into account the inherent characteristic of brain networks, but also captures multi-level (from local to global) topological properties of nodes in brain networks, which are essential for defining the similarity measure of brain networks. To validate the efficacy of our method, we perform extensive experiments on subjects with baseline functional magnetic resonance imaging data obtained from the Alzheimer's disease neuroimaging initiative database. Experimental results demonstrate that the proposed method outperforms several state-of-the-art graph-based methods in MCI classification.
ПРОЕКТИРОВАНИЕ ЛЕСНЫХ УЧАСТКОВ В ЦЕЛЯХ РАЗМЕЩЕНИЯ ЛИНЕЙНЫХ ОБЪЕКТОВ: ТЕОРИЯ, ОПЫТ СПЕЦИАЛИСТОВ ХМАО-ЮГРЫ
Creators: name: МЕЗЕНИНА ОЛЬГА БОРИСОВНА
name: НАГИМОВ ЗУФАР ЯГФАРОВИЧ
name: ЗУЕВА ОЛЬГА ВАЛЕРЬЕВНА
name: КЮРШЕЕВА ОЛЬГА ВАСИЛЬЕВНА
Publisher: name: Московский экономический журнал
Year: 2019
Subjects: ЛЕСНОЙ УЧАСТОК
ЛИНЕЙНЫЙ ОБЪЕКТ
ПРОЕКТ МЕЖЕВАНИЯ ТЕРРИТОРИИ
ПРОЕКТНАЯ ДОКУМЕНТАЦИЯ
ПРОЕКТ ОСВОЕНИЯ ЛЕСОВ
FOREST PLOT
LINEAR OBJECT
LAND SURVEYING PROJECT
PROJECT DOCUMENTATION
FOREST DEVELOPMENT PROJECT

description: В данной статье кратко представлены теоретические аспекты создания проекта межевания территории, который разрабатывается в целях определения местоположения границ образуемых и изменяемых земельных участков и указали, что подготовка данного проекта регламентируется статьей 43 Градостроительного кодекса РФ от 29.12.2004 N 190-ФЗ (ред. от 31.12.2014). Отметили факт, что проект межевания территории необходим в случаях, предусмотренных Земельным кодексом (п.3. статьи 11.3. Земельного кодекса РФ), в том числе при образовании земельных участков для размещения линейных объектов федерального, регионального или местного значения. Также авторы показали необходимость при создании проекта межевания территории для освоения земель лесного фонда под линейные объекты сохранить работу с проектной документацией, которую упразднил законодатель для данных объектов, для использования ее при подготовке проекта межевания и проекта освоения лесов.
Additional file 1: of Impact of species and antibiotic therapy of enterococcal peritonitis on 30-day mortality in critical care—an analysis of the OUTCOMEREA database
Creators: name: Morvan, Anne-Cécile
name: Hengy, Baptiste
name: Garrouste-Orgeas, Maïté
name: Ruckly, Stéphane
name: Forel, Jean-Marie
name: Argaud, Laurent
name: Rimmelé, Thomas
name: Bedos, Jean-Pierre
name: Azoulay, Elie
name: Dupuis, Claire
name: Mourvillier, Bruno
name: Schwebel, Carole
name: Timsit, Jean-François
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Flowchart. IAI = intraabdominal infection. (DOCX 46 kb)
svReg: Structural varying-coefficient regression to differentiate how regional brain atrophy affects motor impairment for Huntington disease severity groups
Creators: name: Kim, Rakheon
name: Garcia, Tanya P.
name: Mueller, Samuel
Publisher: name: Wiley
Year: 2021

description: For Huntington disease, identification of brain regions related to motor impairment can be useful for developing interventions to alleviate the motor symptom, the major symptom of the disease. However, the effects from the brain regions to motor impairment may vary for different groups of patients. Hence, our interest is not only to identify the brain regions but also to understand how their effects on motor impairment differ by patient groups. This can be cast as a model selection problem for a varying-coefficient regression. However, this is challenging when there is a pre-specified group structure among variables. We propose a novel variable selection method for a varying-coefficient regression with such structured variables and provide a publicly available R package svreg for implementation of our method. Our method is empirically shown to select relevant variables consistently. Also, our method screens irrelevant variables better than existing methods. Hence, our method leads to a model with higher sensitivity, lower false discovery rate and higher prediction accuracy than the existing methods. Finally, we found that the effects from the brain regions to motor impairment differ by disease severity of the patients. To the best of our knowledge, our study is the first to identify such interaction effects between the disease severity and brain regions, which indicates the need for customized intervention by diseaseÂ severity.
The baryon spectroscopy: strong decays and strange suppression
Creators: name: Garcıa-Tecocoatzi, H.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: In this contribution, we present the open-flavor strong decays of light baryons computed within the framework of quark model. The transition amplitudes are computed using a modified $^3P_0$ operator, where a mechanism strange suppression is taken into account. Also we discus the strange suppression within an extension of the quark model.
description: ( 6 pages, 2 figures, nvited talk presented at Symposium on Nuclear Physics, January 4-7 2017, Cocoyoc(Mexico))
Additional file 4: Figure S2. of Cattle infection response network and its functional modules
Creators: name: Beiki, Hamid
name: Pakdel, Abbas
name: Ardeshir Javaremi
name: Masoudi-Nejad, Ali
name: Reecy, James
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Functional analysis of the â light yellowâ module genes. Over-represented GO/pathway terms were grouped based on kappa statistics [62]. The size of each category within a pie chart represents the number of included terms. Only the most significant GO/ terms within groups were labeled. GO/pathway terms are represented as nodes, and the node size represents the term enrichment significance, while the edges represent significant similarity between categories. (A) Representative biological processes interactions among module genes. (B) Representative molecular function interactions among module genes. (C) Representative Reactome analysis interactions among module genes. (PDF 1482Â kb)
КРУПНЫЕ КОМПАНИИ В РАЗВИТИИ РОЗНИЧНОЙ ТОРГОВЛИ РЕГИОНОВ СИБИРИ
Creators: name: ГРИГОРЬЕВА МАРИНА АЛЕКСАНДРОВНА
Publisher: name: Московский экономический журнал
Year: 2019
Subjects: КРУПНАЯ КОМПАНИЯ
РОЗНИЧНАЯ ТОРГОВЛЯ
РОЗНИЧНЫЕ ТОРГОВЫЕ СЕТИ
ТИПОЛОГИЯ
РЕГИОН
СИБИРСКИЙ ФЕДЕРАЛЬНЫЙ ОКРУГ
LARGE COMPANY
RETAIL
RETAIL CHAINS
TYPOLOGY
REGION
SIBERIAN FEDERAL DISTRICT

description: В статье рассмотрена роль крупных компаний в развитии розничной торговли регионов Сибирского федерального округа. Отмечено, что крупные торговые компании представлены преимущественно сетевыми структурами. Выявлены различия регионов Сибирского федерального округа по представленности крупных торговых компаний и уровню развития розничной торговли. Представленность крупных торговых компаний характеризовалась их количеством и средним размером выручки. Для определения уровня развития розничной торговли использовались как показатели в расчете на душу населения, так и показатели ее доступности для населения. В результате были выделены 3 типа регионов Сибири с территориальными особенностями.
Systematic review of illness uncertainty management interventions for cancer patients and their family caregivers
Creators: name: Song, Lixin
name: Guan, Ting
name: Qan'ir, Yousef
Publisher: name: Springer Nature
Year: 2021

description: Purpose

Illness uncertainty pervades individuals’ experiences of cancer across the illness trajectory and is associated with poor psychological adjustment. This review systematically examined the characteristics and outcomes of interventions promoting illness uncertainty management among cancer patients and/or their family caregivers.
Methods

PubMed, Scopus, PsycINFO, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase, and Cochrane Database of Systematic Reviews were systematically searched for relevant literature. We included randomized controlled trials (RCTs) and quasi-experimental studies focusing on interventions for uncertainty management in cancer patients and/or their family caregivers.
Results

Our database searches yielded 26 studies. Twenty interventions were only offered to cancer patients, who were mostly elder, female, and White. All interventions included informational support. Other intervention components included emotional support, appraisal support, and instrumental support. Most interventions were delivered in person and via telephone (n = 8) or exclusively in person (n = 7). Overall, 18 studies identified positive intervention effects on illness uncertainty outcomes.
Conclusion

This systematic review foregrounds the promising potential of several interventions—and especially multi-component interventions—to promote uncertainty management among cancer patients and their family caregivers. To further improve these interventions’ effectiveness and expand their potential impact, future uncertainty management interventions should be tested among more diverse populations using rigorous methodologies.
Precise Real-Time Navigation of LEO Satellites Using a Single-Frequency GPS Receiver and Ultra-Rapid Ephemerides
Creators: name: Sun, Xiucong
name: Han, Chao
name: Chen, Pei
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Precise (sub-meter level) real-time navigation using a space-capable single-frequency global positioning system (GPS) receiver and ultra-rapid (real-time) ephemerides from the international global navigation satellite systems service is proposed for low-Earth-orbiting (LEO) satellites. The C/A code and L1 carrier phase measurements are combined and single-differenced to eliminate first-order ionospheric effects and receiver clock offsets. A random-walk process is employed to model the phase ambiguities in order to absorb the time-varying and satellite-specific higher-order measurement errors as well as the GPS clock correction errors. A sequential Kalman filter which incorporates the known orbital dynamic model is developed to estimate orbital states and phase ambiguities without matrix inversion. Real flight data from the single-frequency GPS receiver onboard China's SJ-9A small satellite are processed to evaluate the orbit determination accuracy. Statistics from internal orbit assessments indicate that three-dimensional accuracies of better than 0.50 m and 0.55 mm/s are achieved for position and velocity, respectively.
description: 25 pages, 6 figures, Ready for publication in Aerospace Science and Technology, 2017
Acknowledging local sociality in disaster recovery: a longitudinal, qualitative study
Creators: name: Okada, Tetsuya
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Formal recovery, reconstruction and risk reduction efforts put in place in response to major disaster events are designed to redevelop infrastructure and services for, and improve the longer-term safety of, the affected populations. However, these efforts often rely on top-down approaches that neglect the impact on and the presence of local people’s everyday lives in and with their communities (local sociality). As a result, top-down recovery and reconstruction approaches may misjudge engagement with disaster-impacted communities. Existing and emerging power-relations tend to influence the aims and processes of the recovery and marginalise the voices of the affected populations, particularly the most vulnerable. This thesis explores these issues in four case studies: the towns of St George and Grantham, in Queensland, Australia, both of which were severely impacted by flooding events between 2010 and 2012, and the Japanese towns of Koizumi and Namie, which sustained devastating damage from the Tohoku earthquake and tsunami and in the case of Namie, contamination from the Fukushima nuclear reactor in 2011. This study identifies a critical coherence in the human, social and political issues and challenges across all study areas, despite differences in the country, physical attributes of the hazards, types of damage and responses. In particular, the commonality identified across four different cases illuminate the importance of local sociality that is highly valued by the disaster-impacted people but often overlooked or downplayed by others. The adopted qualitative, longitudinal research approach using semi-structured interviews through multiple site visits captured and identified long-term impacts and transitions in each study area involving individuals, households, local community groups, support persons and organisations and government officials.
Additional file 1 of A highly thermotolerant laccase produced by Cerrena unicolor strain CGMCC 5.1011 for complete and stable malachite green decolorization
Creators: name: Yao, Yanhua
name: Zhou, Guimei
name: Lin, Yonghui
name: Xu, Xinqi
name: Yang, Jie
Publisher: name: figshare
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Additional figures and tables.
Intuitive Joint Priors for Bayesian Linear Multilevel Models: The R2D2M2 prior
Creators: name: Aguilar, Javier Enrique
name: Bürkner, Paul-Christian
Publisher: name: arXiv
Year: 2022
Subjects: subject: Methodology (stat.ME)
subject: Computation (stat.CO)
subject: FOS: Computer and information sciences

description: The training of high-dimensional regression models on comparably sparse data is an important yet complicated topic, especially when there are many more model parameters than observations in the data. From a Bayesian perspective, inference in such cases can be achieved with the help of shrinkage prior distributions, at least for generalized linear models. However, real-world data usually possess multilevel structures, such as repeated measurements or natural groupings of individuals, which existing shrinkage priors are not built to deal with. We generalize and extend one of these priors, the R2D2 prior by Zhang et al. (2020), to linear multilevel models leading to what we call the R2D2M2 prior. The proposed prior enables both local and global shrinkage of the model parameters. It comes with interpretable hyperparameters, which we show to be intrinsically related to vital properties of the prior, such as rates of concentration around the origin, tail behavior, and amount of shrinkage the prior exerts. We offer guidelines on how to select the prior's hyperparameters by deriving shrinkage factors and measuring the effective number of non-zero model coefficients. Hence, the user can readily evaluate and interpret the amount of shrinkage implied by a specific choice of hyperparameters. Finally, we perform extensive experiments on simulated and real data, showing that our inference procedure for the prior is well calibrated, has desirable global and local regularization properties and enables the reliable and interpretable estimation of much more complex Bayesian multilevel models than was previously possible.
description: 61 pages, 21 figures, 9 tables
РАЗРАБОТКА МОДЕЛИ УСТОЙЧИВОГО ЗЕМЛЕПОЛЬЗОВАНИЯ В ГРАНИЦАХ ЗЕМЕЛЬ ЛЕСНОГО ФОНДА ПРИРОДНОГО ПАРКА "САМАРОВСКИЙ ЧУГАС" ХМАО-ЮГРА
Creators: name: СИМАКОВА ТАМАРА ВЛАДИСЛАВОВНА
name: ЕВТУШКОВА ЕЛЕНА ПАВЛОВНА
Publisher: name: Московский экономический журнал
Year: 2019
Subjects: ЗЕМЛИ ЛЕСНОГО ФОНДА
УСТОЙЧИВОЕ ЗЕМЛЕПОЛЬЗОВАНИЕ
ЛЕСОТАКСАЦИОННЫЕ ОБСЛЕДОВАНИЯ
ОЦЕНКА ПРИГОДНОСТИ
АНАЛИЗ БЛАГОПРИЯТНОСТИ
FOREST LANDS
SUSTAINABLE LAND USE
FOREST TAX SURVEYS
SUITABILITY ASSESSMENT
FAVORABILITY ANALYSIS

description: В статье рассматривается анализ использования лесов по ряду признаков, учитываемых при лесотаксационных обследованиях. В основу работу положены методические подходы организации и оценки использования лесов природного парка. В результате исследования проведен комплексный анализ состояния и использования земель лесного фонда, установлены особенности использования, в результате чего (методом моделирования) исследуемая территория разбита на кластеры (зоны благоприятности). С учетом установленных особенностей и выделенных кластеров разработаны мероприятия по снижению или ликвидации негативных изменений на местности, направленные на рациональное использование земель лесного фонда в границах исследуемой территории.