cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
International relations and the Himalaya: Connecting ecologies, cultures and geopolitics
Creators: name: Davis, Alexander
name: Gamble, Ruth
name: Roche, Gerald
name: Gawne, Lauren
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: This article examines international relations (IR)'s approach to the Himalaya. We argue that the possibility of violent conflict over contested international borders is not the region's primary international challenge. Rather, slow violence inflicted by state-building and militarisation, intimately connected to geopolitical tensions, threaten the region's ecologies, cultures and languages. The Himalaya is home to three biodiversity hotspots and a mosaic of ethnic groups, many of whom speak threatened languages. Its ice-deposits feed most of Asia's large rivers. In recent years, India and China have pursued large-scale infrastructure development in the region, enabling greater militarisation and extraction, and a tourist rush. These threats are amplified by climate change, which is occurring in the Himalaya at twice global averages, contributing to landslides, flooding, and droughts. However, the region's complexity is not matched by IR's theorisations, which overwhelmingly focus on the possibility of violent conflict between state actors. We argue that IR's analysis of the region must go beyond a states-and-security, Delhi-Beijing-Islamabad centred approach, to look at the numerous interconnections between its geopolitics, cultures and ecologies. We suggest this can be accomplished through incorporating more interdisciplinary analysis, and through focusing on the interaction between the organisation of political authority and the region's environment.
Impact of endurance exercise on the heart of cyclists: a systematic review and meta-analysis
Creators: name: Wundersitz, Daniel
name: Gordon, Brett
name: CJ Lavie
name: V Nadurata
name: Kingsley, Michael
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 Elsevier Inc. Objective: To compare heart structure and function in endurance athletes relative to participants of other sports and non-athletic controls in units relative to body size. A secondary objective was to assess the association between endurance cycling and cardiac abnormalities. Patients and methods: Five electronic databases (CINAHL, Cochrane Library, Medline, Scopus, and SPORTdiscus) were searched from the earliest record to 14 December 2019 to identify studies investigating cardiovascular structure and function in cyclists. Of the 4865 unique articles identified, 70 met inclusion criteria and of these, 22 articles presented 10 cardiovascular parameters in units relative to body size for meta-analysis and five presented data relating to incidence of cardiac abnormalities. Qualitative analysis was performed on remaining data. The overall quality of evidence was assessed using GRADE. Odds ratios were calculated to compare the incidence of cardiac abnormality. Results: Heart structure was significantly larger in cyclists compared to non-athletic controls for left ventricular: mass; end-diastolic volume, interventricular septal diameter and internal diameter; posterior wall thickness, and end-systolic internal diameter. Compared to high static and high dynamic sports (e.g., kayaking and canoeing), low-to-moderate static and moderate-to-high dynamic sports (e.g., running and swimming) and moderate-to-high static and low-to-moderate dynamic sports (e.g., bodybuilding and wrestling), endurance cyclists end-diastolic left ventricular internal diameter was consistently larger (mean difference 1.2–3.2 mm/m2). Cardiac abnormalities were higher in cyclists compared to controls (odds ratio: 1.5, 95%CI 1.2–1.8), but the types of cardiac abnormalities in cyclists were not different to other athletes. Conclusion: Endurance cycling is associated with a larger heart relative to body size and an increased incidence of cardiac abnormalities relative to controls.
Supplementary document for Topological spatial differentiation via complex amplitude filtering in Fourier space - 6424335.pdf
Creators: name: Yan, Ding
name: Qi, Tong
name: Liu, Tingting
name: Chen, Yizhe
name: Gao, Wei
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
What happens after school? Exploring post-school outcomes for a group of autistic and non-autistic Australian youth
Creators: name: Flower, Rebecca L
name: Richdale, Amanda L
name: Lawson, Lauren P
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020, Springer Science+Business Media, LLC, part of Springer Nature. Young autistic Australians are less likely to attend higher education and have lower employment rates than non-autistic Australians (in: Australian Bureau of Statistics, Survey of disability, ageing and carers Australia: Summary of Findings 2018. Australian Bureau of Statistics, Canberra, 2019a). Few studies have examined post-school outcomes among this population. Using data from the first phase of a national longitudinal study including autistic (n = 79) and non-autistic (n = 107) 17–25-year olds, we found young autistic adults were (a) less likely to be employed, (b) more likely to attend technical and further education (TAFE) than university, (c) more likely to enrol in higher education on a part-time basis and (d) less likely to be engaged in both higher education and employment, than their non-autistic peers. Findings highlight a need to understand post-school trajectories of young autistic adults.
What happens after school? Exploring post-school outcomes for a group of autistic and non-autistic Australian youth
Creators: name: Flower, Rebecca
name: Richdale, Amanda
name: Lawson, Lauren
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 39
subject: Education
classificationCode: 3902
subject: Education policy, sociology and philosophy
classificationCode: 3904
subject: Specialist studies in education
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: No description supplied.
title: Data Compression in Statistical Learning by Means of Quantized Random Projection
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 2020

description: This dissertation explores advancements in random projection, a method of dimensionality reduction that reduces the number of variables in a dataset via multiplication with a smaller, randomly generated matrix. Compared to other dimensionality reduction methods, random projection has very fast operation time and a small memory footprint, at the cost of potentially more information loss. This dissertation investigates the effects of quantization on random projection, particularly in conjunction with machine learning algorithms. We demonstrate that in many settings the amount information loss can be managed to be of minimal practical consequence. Beyond establishing an effective method of data compression for machine learning, this dissertation provides formulae and code that allow future researchers, or anyone who seeks to reduce their data under certain circumstances, to determine an optimal compression scheme. We also feel that the structure of our proofs can be generalized to suit them a variety of machine learning algorithms, or quantization methods. The first two chapters of this dissertation introduce the topic and provide background information, respectively. Chapter 2 goes into significant algebraic detail to provide context for understanding the following chapters. Chapter 3 investigates quantization, with two different methods of quantization compared both individually and when combined with random projection. It focuses on proofs on bounds of mean squared errors. Chapter 4 focuses on random projection in conjunction with spectral clustering, an algorithm whose strengths align well with those of random projection. Again the focus is on analyzing bounds. Finally, chapter 5 explores these algorithms through experiments. Two simulation experiments further explore the technical details of spectral clustering and random projection, before we close with some real data experiments that compare random projection to principal components analysis.
ВИДЫ ТРОФИЧЕСКИХ ЯЗВ СЛИЗИСТОЙ ОБОЛОЧКИ ПОЛОСТИ РТА У ПАЦИЕНТОВ ПЕРЕНЕСШИХ COVID-19
Creators: name: Саидова, Мухлиса
Publisher: name: Zenodo
Year: 2024

description: Статья посвящена актуальной проблеме современной стоматологии: трофическим язвам слизистой оболочки полости рта у постковидных пациентов. По данным различных авторов у пациентов, перенесших COVID-19,  в полости рта встречаются многочисленные осложнения в виде геморрагических проявлений, ангулярного хейлита, кандидоза, пигментации, а также трофических язв (Хабадзе З.С., соавт., 2020). Задача стоматолога – своевременно диагностировать стоматологические проявления у пациентов, перенесших коронавирусную инфекцию, и выбрать наиболее адаптированный алгоритм их лечения в зависимости от клинических проявлений в полости рта.
The Trade Development Among OIC Countries: Exploring Challenges, Opportunities, and the Impact of the Covid-19 Pandemic
Creators: name: Bhatti, Ishaq
name: Ghouse, Ghulam
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 4404
subject: Development studies
classificationCode: 380110
subject: International economics
classificationCode: 480308
subject: International trade and investment law
classificationCode: 44
subject: Human society

description: This paper investigates the factor determining the impact of trade development, challenges, and opportunities among various OIC countries. It studies the impact of socioeconomics, geo-political and cultural, factors using data between 2014 to 2022. The selected OIC countries from diverse regions, namely South and Southeast Asia, South America, Europe, Africa, and Central Asia. The study’s sample includes 50 countries out of a total of 57 OIC member nations. The paper employs a two-step GMM model to address endogeneity issues related to institutional variables. To account for the impact of the Covid-19 pandemic on trade, we have included a Covid-19 dummy variable in the model. Our results reveal that the Covid-19 dummy variable is significant in all models, indicating its significant impact on trade. Furthermore, most of the variables included in the study are found to be significant in all models. Overall, this study provides valuable insights into the factors that influence trade in OIC countries and the impact of the Covid-19 pandemic on trade.
Serosurveillance and Molecular Investigation of Wild Deer in Australia Reveals Seroprevalence of Pestivirus Infection
Creators: name: Huaman Torres, Jose Luis Alfredo
name: Pacioni, C
name: Forsyth, DM
name: Pople, A
name: Hampton, JO
name: Carvalho, Ana-Teresa
name: Helbig, Karla
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3107
subject: Microbiology

description: Since deer were introduced into Australia in the mid-1800s, their wild populations have increased in size and distribution, posing a potential risk to the livestock industry, through their role in pathogen transmission cycles. In comparison to livestock, there are limited data on viral infections in all wildlife, including deer. The aim of this study was to assess blood samples from wild Australian deer for serological evidence of exposure to relevant viral livestock diseases. Blood samples collected across eastern Australia were tested by ELISA to detect antigens and antibodies against Pestivirus and antibodies against bovine herpesvirus 1. A subset of samples was also assessed by RT-PCR for Pestivirus, Simbu serogroup, epizootic hemorrhagic disease virus and bovine ephemeral fever virus. Our findings demonstrated a very low seroprevalence (3%) for ruminant Pestivirus, and none of the other viruses tested were detected. These results suggest that wild deer may currently be an incidental spill-over host (rather than a reservoir host) for Pestivirus. However, deer could be a future source of viral infections for domestic animals in Australia. Further investigations are needed to monitor pathogen activity and quantify possible future infectious disease impacts of wild deer on the Australian livestock industry.
Transnational Social Workers’ Understanding of Australian First Nations Perspectives in Statutory Child Protection
Creators: name: Modderman, Corina
name: McMahon, Mishel
name: Threlkeld, Guinever
name: McPherson, Lynne M
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 44
subject: Human society
classificationCode: 4407
subject: Policy and administration
classificationCode: 4409
subject: Social work

description: https://www.tandfonline.com/doi/full/10.1080/0312407X.2020.1771389 
Abstract: Chronic staff shortages and high rates of turnover in child protection programs create opportunities for social work mobility across the world. Australian child protection departments actively recruit social workers from the United Kingdom and Ireland. This strategy may cause tension relating to the application of known Western social work practice and theory and limited understanding of Australian First Nations worldviews. Australia continues to struggle with the ongoing impact of colonisation; First Nations children are overrepresented in child protection service delivery. The research explored the understanding held by overseas-born and -educated social workers from the UK and Ireland (transnational social workers or TNSWs) of Australian First Nations peoples, when they migrate to practice in frontline child protection. Interviews with 13 practitioners across two time points explored social work practice in the transnational context. The study found that the majority of TNSWs had limited understanding of social work in a colonised country. The results provide a foundation to rethink how TNSW practice is influenced by place-related change. This research identified a need to raise transnational social workers’ awareness of Australian First Nations child rearing practices that may lie outside their experiential understanding. IMPLICATIONS Transnational social workers may advance their understanding of First Nations peoples and their perspectives through increasing their awareness of differences in their personal lived experiences from that of Australian First Nations peoples. The practice of cultural humility may reduce harm in transnational child protection practice. Critical reflection may enable the emergence of counter-colonial thinking in child protection practice with Australian First Nations peoples.
Substitute ivory product in illegal wildlife trade: identifying them using morphological and DNA-based analysis in wildlife forensics in India
Creators: name: Vipin Sharma
name: Sharma, Vinita
name: Sharma, Chandra Prakash
name: Surendra Prakash  Goyal
Publisher: name: F1000Research
Year: 2016

description: • The illegal trade of wildlife articles in the form of ivory, bones, horns, skin, hair and their derivatives has cost the lives and existence of many threatened species around the world.

• Increase in the price of ivory, because of short supply and high demand, as a result of ban on sale and display of ivory and its products in India have forced the craftsmen to use ivory substitutes (bones, resins, antlers, plastics and wood) which resembles the ivory to a much extent.

• Thirty two such suspected ivory plates having the paintings of Moghul era on them suspected to be made up of ivory material were seized by the law enforcement authorities at Delhi and were sent to the Wildlife Institute of India, Dehradun, India for the identification of species.

• We successfully identified the species using morphological and DNA based wildlife forensic techniques. The absence of both the fluorescence in response to ultraviolet (UV)-rays and Schreger lines on cross sections proved the non ivory origin of all three seized articles.

• The mitochondrial cyt b gene was sequenced for the identification of species of the seized suspected ivory products. Two suspected ivory plates which were randomly chosen from the seizure were found to be of water buffalo (Bubalus bubalis) on the basis of BLAST search at NCBI, USA and Neighbor-Joining (NJ) tree with high bootstrap values.

• Our results support the earlier reports of using substitute ivory and prove that these type of items still floats in illegal wildlife trade markets.

• Therefore, the development of DNA data base of all species threatened by the wildlife trade, on priority basis, will be very useful in identification of species of origin of seized articles and the implementation of wildlife protection laws and ultimately for the conservation of wild and other species.
title: Conceptualizations of Family and Identity Among Polyamorous Individuals
Creators: name: Roberts, Lester Leroy
Publisher: name: George Mason University
Year: 2017
Subjects: subject: Polyamory
subject: Identity
subject: Non-monogamy
subject: Family
subject: Stigma
subject: Relationships

description: This thesis is an exploration of how polyamorous individuals construct both their families and their own identities in light of their non-traditional approach to relationships. The research draws on ten in-depth interviews with self-identified polyamorists and participant observation of polyamorous communities in the Washington D.C., Northern and Central Virginia, Maryland and West Virginia. Applying Erving Goffman’s theories about stigma and moral career, these interviews indicate that polyamorous individuals come to hold their identity as polyamorists through moral career paths starting with an openness to non-monogamy influenced by their history with family of origin, sexual orientation, religious beliefs (or the lack thereof), and other subcultural interests, particularly science fiction. Polyamorists come to such an identity as a way to become more moral people in their own view and build families of choice (household, extended and tribe) around them from, mainly, other members of the polyamorous community.
Experiences, reflections, gripes and a wish list: representing how academic clinicians relate to the publishing industry
Creators: name: Matthews, Philippa C.
Publisher: name: F1000Research
Year: 2016

description: These slides and data are taken from a presentation to be given to the ALPSP (Association of Learned and Professional Society Publishers) conference in September 2016. For more information, visit http://www.alpsp.org/.

The aim is to summarise some of the challenges in the relationship between academic medicine and publishing, in order to prompt dialogue about how we optimise data availability and stream-line the publication process. The presentation includes discussion of impact factor, the role of social media, the peer review process and society publishing.

These on-line slides present the complete results of a questionnaire about publishing that was completed by academics and clinicians, focusing primarily on an academic cohort in Oxford, UK. As well as featuring highlights from the data, the unabridged questionnaire results are presented here in the form of an appendix.
title: The American National Theatre and Academy. Chartered by Congress. Senate Bill 2642. July, 1935
Creators: name: Davis, Blevins
Publisher: name: George Mason University
Year: 1995
Subjects: subject: ANTA purpose
subject: Experimental Theatre
subject: ANTA Council
subject: ANTA Board of Directors
subject: Grange, National
subject: Office of War Information
subject: Office of Education, U.S.
subject: National Education Association
subject: State, U.S. Department of
subject: The Old Vic Co.
subject: Davis, Blevins
subject: Massey, Raymond
subject: Sherwood, Robert E.
subject: Roosevelt, Eleanor
subject: Thomas, Elbert
subject: Freedley, Vinton
subject: Campbell, C. Lawton
subject: Gilder, Rosamond
subject: Crothers, Rachel
subject: Freedley, George
subject: Ewing, Sherman
subject: Porterfield, Robert
subject: Breen, Robert
subject: Friedlander, Emil
subject: Rose, Billy
subject: Golden, John
subject: Larson, Jens Frederick
subject: Morris, William Jr.
subject: Falk, Sawyer
subject: Derwent, Clarence
subject: Harkness, Edward

description: Senate Bill 2642 with pencil notation at top of p. 1 - Blevins Davis. For Pres. T. 7/22/46.
Maximizing cognition in mild cognitive impairment and early stage dementia
Creators: name: Regan, Bridget
name: Wells, Yvonne
name: O'Halloran, Paul
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Cognitive interventions aim to positively impact cognition and ideally enable function in day-to-day life. A range of approaches have been developed for people with mild cognitive impairment (MCI) and early stage dementia, including cognitive training, cognitive strategy training, single component training, and cognitive rehabilitation. Cognitive rehabilitation shows promise as the only approach that specifically tailors the intervention to the goals of individuals, whereas the other approaches typically utilize a standardized approach. A growing body of research suggests that individualized cognitive rehabilitation helps people reach their goals in day-to-day life and may even delay the onset of institutionalization. However, there is less evidence to suggest that cognitive rehabilitation impacts on broader outcomes such as quality of life, mood, and self-efficacy. Implications for future research and clinical practice are discussed, including the need for more research into cognitive rehabilitation in MCI groups and direct comparisons with other approaches.

------------
With an impact on millions globally, and billions of research dollars being invested in dementia research, this book will stimulate research in the area and inform researchers.
On the formal representation of the Australian spent conviction scheme
Creators: name: Governatori, Guido
name: Romeu, Pompeu Casanovas
name: De Koker, Louis
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020, Springer Nature Switzerland AG. We discuss how to use Defeasible Deontic Logic to provide a formal representation of the Commonwealth of Australia spent conviction schema (Part VII C of the Crimes Act (1914)). The formalisation is directly written and implemented in Turnip (a modern implementation of Defeasible Deontic Logic).
Smart home and communication technology for people with disability: a scoping review
Creators: name: Jamwal, Rebecca
name: Jarman, Hannah
name: Roseingrave, E
name: Douglas, Jacinta
name: Winkler, Dianne
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 4007
subject: Control engineering, mechatronics and robotics
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4201
subject: Allied health and rehabilitation science
classificationCode: 4203
subject: Health services and systems

description: Purpose: The links between disability, activity limitation and participation restriction are well established. Recent and continued advancement of technology, particularly smart home and communication technologies, presents new ways in which some of the limitations and restrictions experienced by people with disabilities can be overcome. The aim of this scoping review was to explore the impact of smart home and communication technology on the outcomes of people with disabilities and complex needs. Method: This review involved systematic searching of four databases, hand searches and data extraction. Eligibility criteria included [1] participant outcomes of [2] technology used within the home [3] among adults with a disability and complex needs. Results: Of the 2400 studies identified, 21 met our inclusion criteria. Studies were characterized by significant diversity in relation to disability and type of technology. Overall, technology appeared to improve independence, participation and quality of life among people with a disability and complex needs. Despite this, ethical considerations were raised given the vulnerability of this population, including potential risks through social participation and privacy concerns of using monitoring technology. Conclusions: Smart home and communication technology can improve outcomes for people living with disabilities and complex needs. However, a number of factors impact the successful implementation of technology, including personalization, flexibility and ongoing support to the person with a disability and their close others. Future research should utilize high-quality study designs and established measures of important outcomes for this group.IMPLICATIONS FOR REHABILITATION: There is a broad range of smart home and communication technology devices and systems available that may support the independence and participation of people with disabilities and complex needs; however, high-quality evidence documenting the impact of technology is lacking. Soft-technology supports, including assessment, training and evaluation of technology implementation, may play just as important a role in shaping outcomes as the technology itself. Systematic research is required to ensure there is quality evidence to inform investment in both technologies, and the soft-technology supports that promote its successful use.
Smart home and communication technology for people with disability: a scoping review
Creators: name: Jamwal, Rebecca
name: Jarman, Hannah
name: Roseingrave, E
name: Douglas, Jacinta
name: Winkler, Dianne
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Purpose: The links between disability, activity limitation and participation restriction are well established. Recent and continued advancement of technology, particularly smart home and communication technologies, presents new ways in which some of the limitations and restrictions experienced by people with disabilities can be overcome. The aim of this scoping review was to explore the impact of smart home and communication technology on the outcomes of people with disabilities and complex needs. Method: This review involved systematic searching of four databases, hand searches and data extraction. Eligibility criteria included [1] participant outcomes of [2] technology used within the home [3] among adults with a disability and complex needs. Results: Of the 2400 studies identified, 21 met our inclusion criteria. Studies were characterized by significant diversity in relation to disability and type of technology. Overall, technology appeared to improve independence, participation and quality of life among people with a disability and complex needs. Despite this, ethical considerations were raised given the vulnerability of this population, including potential risks through social participation and privacy concerns of using monitoring technology. Conclusions: Smart home and communication technology can improve outcomes for people living with disabilities and complex needs. However, a number of factors impact the successful implementation of technology, including personalization, flexibility and ongoing support to the person with a disability and their close others. Future research should utilize high-quality study designs and established measures of important outcomes for this group.IMPLICATIONS FOR REHABILITATION There is a broad range of smart home and communication technology devices and systems available that may support the independence and participation of people with disabilities and complex needs; however, high-quality evidence documenting the impact of technology is lacking. Soft-technology supports, including assessment, training and evaluation of technology implementation, may play just as important a role in shaping outcomes as the technology itself. Systematic research is required to ensure there is quality evidence to inform investment in both technologies, and the soft-technology supports that promote its successful use.
Research interest, experience and confidence of allied health professionals working in medical imaging: a cross-sectional survey
Creators: name: Dennett, Amy
name: Cauchi, T
name: Harding, Katherine
name: Kelly, Paul
name: Ashby, G
name: Taylor, Nicholas
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Introduction: There is growing interest in developing research culture and opportunities for allied health professionals working in medical imaging. However, little attention has been given to identifying the research interest and needs of this group relative to the other allied health professions. We aimed to measure self-reported research participation, interest, experience and confidence of allied health professionals working in medical imaging and compare the findings to clinicians working in allied health therapies. Methods: A cross-sectional survey of allied health professionals from medical imaging (radiographers, sonographers and nuclear medicine technologists) was conducted. The primary outcome, the Research Spider survey, measures 10 domains of research interest/experience/confidence on a 5-point Likert scale. Results were compared to allied health therapy data. Results: Responses were received by 82 medical imaging allied health professionals (65% response rate). Overall, medical imaging professionals rated themselves as having ‘some interest’ and ‘little experience or confidence’ in research. There was no difference in interest, experience and confidence among different imaging professions (interest P = 0.099, experience P = 0.380, confidence P = 0.212) or allied health therapists (interest P = 0.137, experience P = 0.363, confidence P = 0.791). Participants reported greatest interest in finding and reviewing literature and lowest interest in applying for funding. Conclusion: There are strong similarities between medical imaging allied health professionals and allied health therapy professionals. Therefore, strategies used to promote research culture in allied health therapy professions could be leveraged to provide opportunities for medical imaging allied health professionals.
Development of a web-based resource for parents of young children newly diagnosed with autism: participatory research design
Creators: name: Rabba, Aspasia Stacey
name: Dissanayake, Anne
name: Barbaro, Josephine
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: Background The internet provides an ideal avenue to share information, advice, and support regarding autism. However, many websites lack quality control and rarely provide a one-stop resource for families to access necessary, evidence-based information. Objective This study aims to use participatory action research (PAR) with end users (ie, parents) and clinicians to develop a web-based resource (Pathways Beyond Diagnosis) to improve timely access to quality, evidence-based information, and support for families after their child is diagnosed with autism. Methods The PAR approach involves 4 phases: (1) cooperative researcher-stakeholder planning, (2) cooperative researcher-stakeholder–based action, (3) stakeholder observation, and (4) cooperative researcher-stakeholder reflection. A total of 15 participants (parents, n=3; clinicians, n=9; and researchers, n=3) attended individual or group participatory design workshops. This was followed by the translation of knowledge and ideas generated during the workshops to produce mockups of webpages and content, rapid prototyping, and one-on-one consultations with end users to assess the usability of the website developed. Results A total of 3 participatory design workshops were held with the participants, each followed by a knowledge translation session. At the end of the PAR cycle, an alpha prototype of the website was built and a series of one-on-one end user consultation sessions were conducted. The PAR cycle revealed the importance of 6 key topic areas (understanding autism, accessing services, support, gaining funding, putting it all together, and looking into the future) associated with the time of diagnosis, which were incorporated into the beta version of the website. Conclusions The development of the Pathways Beyond Diagnosis website using PAR ensures that families have ready access to practical and evidence-based information following a young child’s diagnosis. The website guides families to access relevant, reputable, and evidence-based information in addition to summarizing key challenges encountered after diagnosis (ie, grief, sharing the diagnosis) and the importance of self-care.
The emerging role of the RNA-binding protein SFPQ in neuronal function and neurodegeneration
Creators: name: Lim, Yee Wa
name: James, Dylan
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. RNA-binding proteins (RBPs) are a class of proteins known for their diverse roles in RNA biogenesis, from regulating transcriptional processes in the nucleus to facilitating translation in the cytoplasm. With higher demand for RNA metabolism in the nervous system, RBP misregulation has been linked to a wide range of neurological and neurodegenerative diseases. One of the emerging RBPs implicated in neuronal function and neurodegeneration is splicing factor proline-and glutamine-rich (SFPQ). SFPQ is a ubiquitous and abundant RBP that plays multiple regulatory roles in the nucleus such as paraspeckle formation, DNA damage repair, and various transcriptional regulation processes. An increasing number of studies have demonstrated the nuclear and also cytoplasmic roles of SFPQ in neurons, particularly in post-transcriptional regulation and RNA granule formation. Not surprisingly, the misregulation of SFPQ has been linked to pathological features shown by other neurodegenerative disease-associated RBPs such as aberrant RNA splicing, cytoplasmic mislocalization, and aggregation. In this review, we discuss recent findings on the roles of SFPQ with a particular focus on those in neuronal development and homeostasis as well as its implications in neurodegenerative diseases.
A novel 8-parameter integrable map in R4
Creators: name: Quispel, Gilles
name: McLaren, David
name: Van Der Kamp, Pieter
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 49
subject: Mathematical sciences
classificationCode: 51
subject: Physical sciences
subject: FOS: Physical sciences
classificationCode: 5106
subject: Nuclear and plasma physics

description: No description supplied
Sex-induced, male-specific sleep loss in Antechinus
Creators: name: Zaid, Erika
name: Rainsford, Frederick
name: Meerlo, P
name: Lesku, John
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: No description supplied
Reconstructing the depositional history and age of fossil-bearing palaeokarst: a multidisciplinary example from the terminal Pliocene Aves Cave Complex, Bolt's farm, South Africa
Creators: name: Edwards, Tara R
name: Pickering, Robyn
name: Mallett, Tom
name: Herries, Andrew
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: This research contributes to understanding how Bolt's Farm developed the unprecedented high density of palaeokarst observed today, by offering the first evidence that currently discrete localities were once connected as a single cave system.
Factors that influence the quality of paid support for adults with acquired neurological disability: scoping review and thematic synthesis
Creators: name: Topping, Megan Ciara
name: Douglas, Jacinta
name: Winkler, Dianne
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4201
subject: Allied health and rehabilitation science
classificationCode: 44
subject: Human society

description: Purpose: Theoretically, individualised funding schemes empower people with disability (PWD) to choose high quality support services in line with their needs and preferences. Given the importance of support, the aim of this scoping review was to understand the factors that influence the quality of paid disability support for adults with acquired neurological disability. Methods: A comprehensive scoping review of the published literature from 2009–2019 was conducted on five databases: Medline, CINAHL, Embase, PsycINFO and Scopus. Results: Of the 3391 records retrieved, 16 qualitative articles were eligible for review. Thematic synthesis of the findings revealed six key interrelated themes: (1) choice and control, (2) individualised support, (3) disability support worker (DSW) qualities, (4) DSW competence, (5) PWD–DSW relationship, and (6) accessing consistent support. The themes depict factors influencing the quality of paid disability support from the perspective of PWD, close others and DSWs. Conclusions: Although the evidence base is sparse, the factors identified were in line with international rights legislation and policy ideals. The findings can provide insights to PWD hiring and managing support, and facilitate the delivery of quality disability support. Further research is required to understand the interactions between the factors and how to optimise support in practice.Implications for rehabilitation The quality of paid disability support is determined by a multitude of interrelated factors influenced by the disability support worker’s qualities and competencies, the interaction between the person with disability and the disability support worker, as well as external contextual factors. Optimising choice and control for adults with acquired neurological disability and providing individualised support should be a significant focus for disability support workers. Training modules for disability support workers can be informed by five of the identified themes: (1) choice and control, (2) individualised support, (3) DSW qualities, (4) DSW competence and (5) the relationship between PWD and DSWs.
Factors that influence the quality of paid support for adults with acquired neurological disability: scoping review and thematic synthesis
Creators: name: Topping, Megan Ciara
name: Douglas, Jacinta
name: Winkler, Dianne
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 The Author(s).Published by Informa UK Limited, trading as Taylor & Francis Group. Purpose: Theoretically, individualised funding schemes empower people with disability (PWD) to choose high quality support services in line with their needs and preferences. Given the importance of support, the aim of this scoping review was to understand the factors that influence the quality of paid disability support for adults with acquired neurological disability. Methods: A comprehensive scoping review of the published literature from 2009–2019 was conducted on five databases: Medline, CINAHL, Embase, PsycINFO and Scopus. Results: Of the 3391 records retrieved, 16 qualitative articles were eligible for review. Thematic synthesis of the findings revealed six key interrelated themes: (1) choice and control, (2) individualised support, (3) disability support worker (DSW) qualities, (4) DSW competence, (5) PWD–DSW relationship, and (6) accessing consistent support. The themes depict factors influencing the quality of paid disability support from the perspective of PWD, close others and DSWs. Conclusions: Although the evidence base is sparse, the factors identified were in line with international rights legislation and policy ideals. The findings can provide insights to PWD hiring and managing support, and facilitate the delivery of quality disability support. Further research is required to understand the interactions between the factors and how to optimise support in practice.Implications for rehabilitation The quality of paid disability support is determined by a multitude of interrelated factors influenced by the disability support worker’s qualities and competencies, the interaction between the person with disability and the disability support worker, as well as external contextual factors. Optimising choice and control for adults with acquired neurological disability and providing individualised support should be a significant focus for disability support workers. Training modules for disability support workers can be informed by five of the identified themes: (1) choice and control, (2) individualised support, (3) DSW qualities, (4) DSW competence and (5) the relationship between PWD and DSWs.
Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis
Creators: name: N Popgeorgiev
name: JD Sa
name: L Jabbour
name: Banjara, Suresh
name: TTM Nguyen
name: A Akhavan-E-Sabet
name: R Gadet
name: N Ralchev
name: S Manon
name: MG Hinds
name: HJ Osigus
name: B Schierwater
name: Humbert, Patrick
name: R Rimokh
name: G Gillet
name: Kvansakul, Marc
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). In metazoans, Bcl-2 family proteins are major regulators of mitochondrially mediated apoptosis; however, their evolution remains poorly understood. Here, we describe the molecular characterization of the four members of the Bcl-2 family in the most primitive metazoan, Trichoplax adhaerens All four trBcl-2 homologs are multimotif Bcl-2 group, with trBcl-2L1 and trBcl-2L2 being highly divergent antiapoptotic Bcl-2 members, whereas trBcl-2L3 and trBcl-2L4 are homologs of proapoptotic Bax and Bak, respectively. trBax expression permeabilizes the mitochondrial outer membrane, while trBak operates as a BH3-only sensitizer repressing antiapoptotic activities of trBcl-2L1 and trBcl-2L2. The crystal structure of a trBcl-2L2:trBak BH3 complex reveals that trBcl-2L2 uses the canonical Bcl-2 ligand binding groove to sequester trBak BH3, indicating that the structural basis for apoptosis control is conserved from T. adhaerens to mammals. Finally, we demonstrate that both trBax and trBak BH3 peptides bind selectively to human Bcl-2 homologs to sensitize cancer cells to chemotherapy treatment.
Dynamic self-organising swarm for unsupervised prototype generation
Creators: name: Nguyen, Phan
name: Tran, Binh
name: Lakpriya Alahakoon
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Growing big data has posed a great challenge for machine learning algorithms. To cope with big data, the algorithm has to be both efficient and accurate. Although evolutionary computation has been successfully applied to many complex machine learning tasks, its ability to handle big data is limited. In this paper, we proposed a dynamic self-organising swarm algorithm to learn an effective set of prototypes for big high-dimensional datasets in an unsupervised manner. The novelties of this new algorithm are the energy-based fitness function, the adaptive topological neighbourhood, the growing/shrinking capability, and the efficient learning scheme. Experiments with well-known datasets show that the proposed algorithm can maintain a very compact set of prototypes and achieve competitive predictive performance as compared to other algorithms in the literature. The analyses also show that prototypes generated by the proposed algorithms have a stronger separatability compared to those from other prototype generation algorithms.
The influence of meal size on the digestive energetics of Gould's wattled bat, Chalinolobus gouldii
Creators: name: Walker, Melissa
name: Griffiths, Stephen
name: Jones, CS
name: Robert, Kylie
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 30
subject: Agricultural, veterinary and food sciences
classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 41
subject: Environmental sciences

description: Although variation in meal size is known to have an impact on digestive energetics, there is limited information on how it influences metabolic rate and energy assimilation in insectivorous bats. We investigated the influence of meal size, representing 10% or 20% of an individual's weight, on the digestive energetics of Gould's wattled bat, Chalinolobus gouldii (n = 61 bats). Using open-flow respirometry, we recorded a median resting metabolic rate of 2.0 mL g-1 h-1 (n = 51, range = 0.4-4.8) at an air temperature of 32°C. Median postprandial metabolic rate peaked at 6.5 (range = 3.4-11.6, n = 4) and 8.2 (range = 3.8-10.6, n = 7), representing 3.3-and 4.1-fold increases from resting metabolic rate for the two meal sizes. Using bomb calorimetry, we calculated the calorific value of the two meal sizes, and the calories lost during digestion. Following gut passage times of 120 min (range = 103-172, n = 15) and 124 min (range = 106-147, n = 12), C. gouldii assimilated 88.0% (range = 84.6-93.8, n = 5) and 93.3% (range = 84.0-99.4, n = 10) of the kilojoules available from the 10% and 20% meal sizes, respectively. When fed ad libitum, C. gouldii consumed a mean of 23.2% of their body weight during a single sitting (n = 18, range = 6.3-34.1%). Overall, digestive energetics were not significantly different between 10% or 20% meal sizes. The ability to ingest small and large meals, without compromising the rate or efficiency of calorie intake, indicates that free-ranging C. gouldii are likely limited by food available in the environment, rather than the ability to assimilate energy.