cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Proximal disruptor aided ligation (ProDAL) of kilobase-long RNAs
Creators: name: Zhovmer, Alexander
name: Xiaohui Qu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Hematology
subject: 60506 Virology

description: RNA with site-specific modification is a useful tool for RNA biology studies. However, generating kilobase (kb) -long RNA with internal modification at a site distant from RNA termini remains challenging. Here we report an enhanced splint ligation technique, proximal disruptor aided ligation (ProDAL), which allows adequate efficiency toward this purpose. The key to our approach is using multiple DNA oligonucleotides, ‘proximal disruptors’, to target the RNA substrate sequence next to the ligation site. The binding of disruptors helps to free the ligation site from intramolecular RNA basepairing, and consequently promotes more efficient formation of the pre-ligation complex and a higher overall ligation yield. We used naturally occurring 1.0 kb renilla and 1.9 kb firefly luciferase mRNA sequences to test the efficacy of our approach. ProDAL yielded 9–14% efficiency for the ligation between two RNA substrates, both of which were between 414 and 1313 nucleotides (nt) long. ProDAL also allowed similarly high efficiency for generating kb-long RNA with site-specific internal modification by a simple three-part ligation between two long RNA substrates and a modification-carrying RNA oligonucleotide. In comparison, classical splint ligation yielded a significantly lower efficiency of 0–2% in all cases. We expect that ProDAL will benefit studies involving kb-long RNAs, including translation, long non-coding RNAs, RNA splicing and modification, and large ribonucleoprotein complexes.
Relationship between Indoor Daytime Light Exposure and Circadian Phase Response under Laboratory Free-Living Conditions
Creators: name: Yoshimura, Michitaka
name: Kitamura, Shingo
name: Eto, Norihito
name: Hida, Akiko
name: Katsunuma, Ruri
name: Ayabe, Naoko
name: Motomura, Yuki
name: Nishiwaki, Yuji
name: Negishi, Kazuno
name: Tsubota, Kazuo
name: Mishima, Kazuo
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: In this study, we measured the physical quantity of light (irradiance) in several wavelength bands at eye and wrist level for 8 h under laboratory conditions simulating daily life. Twenty-two healthy male participants (mean age ± SD, 29.95 ± 8.13 years) were able to move freely, and eye-level data were compared with irradiance data obtained at the wrist. We estimated circadian phase shift from the differences of DLMO before and after light exposure while considering natural drift. In addition, we investigated the influence of activities and body positions on light exposure and validated the effect of irradiance on circadian phase response. We found lower average irradiance at eye level compared with wrist level in all three RGB bands. The blue light irradiance measured at eye level was significantly correlated with circadian phase shift, possibly because the irradiance at eye level more accurately reflected its effect on the biological clock than did the measurement at the wrist. It follows that quantitative measurements of wavelength spectra at eye level are necessary to assess the effect of ambient light on the human biological clock.
Intravenous abuse potential study of oxycodone alone or in combination with naltrexone in nondependent recreational opioid users
Creators: name: Backonja, Miroslav
name: Webster, Lynn R.
name: Setnik, Beatrice
name: Almasa Bass
name: Sommerville, Kenneth W.
name: Matschke, Kyle
name: Bimal K. Malhotra
name: Wolfram, Gernot
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Background: ALO-02, comprising pellets of extended-release oxycodone surrounding sequestered naltrexone, is intended to deter abuse. Objective: Determine the abuse potential of intravenous oxycodone combined with naltrexone, which represents simulated crushed ALO-02 in solution, compared with intravenous oxycodone in nondependent, recreational opioid users. Methods: A randomized, double-blind, placebo-controlled, three-way crossover study with naloxone challenge, drug discrimination, and treatment phases. Intravenous treatments included oxycodone hydrochloride 20 mg, oxycodone hydrochloride 20 mg plus naltrexone hydrochloride 2.4 mg (simulated crushed ALO-02 20 mg/2.4 mg), or placebo (0.9% sodium chloride for injection). Primary end points were peak effects (Emax) and area under the effects curve within 2 h postdose (AUE0-2h) on drug liking and high visual analog scales. Results: Thirty-three participants were randomized into treatment phase, and 29 completed all treatments. Study validity was confirmed with statistically significant differences in Emax for drug liking and high (p < 0.0001) between intravenous oxycodone and placebo. Intravenous simulated crushed ALO-02 resulted in significantly lower scores than oxycodone on drug liking (Emax: 58.2 vs. 92.4; AUE0-2h: 104.3 vs. 152.4) and high (Emax: 17.2 vs. 93.1; AUE0-2h: 12.0 vs. 133.6), respectively (p < 0.0001, all comparisons). More participants experienced adverse events after intravenous oxycodone (n = 27 [90%]) versus intravenous simulated crushed ALO-02 (n = 4 [12.5%]) or placebo (n = 2 [6.5%]). Conclusion: Intravenous administration of simulated crushed ALO-02 resulted in significantly lower abuse potential, as assessed by subjective ratings of drug liking and high, than intravenous oxycodone in nondependent, recreational opioid users. This suggests that injection of ALO-02 may not be as desirable to recreational opioid users compared with oxycodone taken for nonmedical reasons.
Relationship between Indoor Daytime Light Exposure and Circadian Phase Response under Laboratory Free-Living Conditions
Creators: name: Yoshimura, Michitaka
name: Kitamura, Shingo
name: Eto, Norihito
name: Hida, Akiko
name: Katsunuma, Ruri
name: Ayabe, Naoko
name: Motomura, Yuki
name: Nishiwaki, Yuji
name: Negishi, Kazuno
name: Tsubota, Kazuo
name: Mishima, Kazuo
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: In this study, we measured the physical quantity of light (irradiance) in several wavelength bands at eye and wrist level for 8 h under laboratory conditions simulating daily life. Twenty-two healthy male participants (mean age ± SD, 29.95 ± 8.13 years) were able to move freely, and eye-level data were compared with irradiance data obtained at the wrist. We estimated circadian phase shift from the differences of DLMO before and after light exposure while considering natural drift. In addition, we investigated the influence of activities and body positions on light exposure and validated the effect of irradiance on circadian phase response. We found lower average irradiance at eye level compared with wrist level in all three RGB bands. The blue light irradiance measured at eye level was significantly correlated with circadian phase shift, possibly because the irradiance at eye level more accurately reflected its effect on the biological clock than did the measurement at the wrist. It follows that quantitative measurements of wavelength spectra at eye level are necessary to assess the effect of ambient light on the human biological clock.
Accelerated process optimization for laser-based additive manufacturing by leveraging similar prior studies
Creators: name: Aboutaleb, Amir M.
name: Linkan Bian
name: Elwany, Alaa
name: Shamsaei, Nima
name: Thompson, Scott M.
name: Tapia, Gustavo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Manufacturing parts with target properties and quality in Laser-Based Additive Manufacturing (LBAM) is crucial toward enhancing the “trustworthiness” of this emerging technology and pushing it into the mainstream. Most of the existing LBAM studies do not use a systematic approach to optimize process parameters (e.g., laser power, laser velocity, layer thickness, etc.) for desired part properties. We propose a novel process optimization method that directly utilizes experimental data from previous studies as the initial experimental data to guide the sequential optimization experiments of the current study. This serves to reduce the total number of time- and cost-intensive experiments needed. We verify our method and test its performance via comprehensive simulation studies that test various types of prior data. The results show that our method significantly reduces the number of optimization experiments, compared with conventional optimization methods. We also conduct a real-world case study that optimizes the relative density of parts manufactured using a Selective Laser Melting system. A combination of optimal process parameters is achieved within five experiments.
Is "Freedom" an Aim of Education?
Creators: name: Abinum, Joseph
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: The purpose of this paper is, to present a discussion, in which we hope to show that "freedom" properly understood cannot be an aim or an ideal of education , and that when ed ucators talk of 'freedom' as an aim or ideal of education, they usually have in mind the development of autonomy.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 13 No 3 (1979)
title: The West with the rest? Exploring the role of UFM Worldwide in the sending of overseas cross-cultural missionaries from the Indonesian church
Creators: name: Prest, Michael Stephen
Publisher: name: Edinburgh Theological Seminary, University of Glasgow
Year: 2022

description: With more cross-cultural missionaries being sent from the majority world than the Western world, it is something of an anomaly that the number of such workers being sent by the Indonesian church remains relatively low. This study considers the place of a Western mission agency such as UFM Worldwide in the sending of mission workers from the Indonesian church, examining the case for the West working with the rest to this end. The theological and biblical analysis of this study emphasises the fundamental place of the local church in mission sending and highlights the breadth of mission sending practice that is described in the New Testament church. This work provides the background to the literature study which seeks to highlight the main strategies adopted by other Western agencies as they have pursued internationalisation agendas, namely expanding international structures into the majority world, as well as financing or taking over emerging mission movements. In highlighting the many dangers of such approaches, it is made clear that at times such practice has hindered the very work it set out to do. Empirical research was then undertaken with 3 Indonesian mission agency leaders in order to contribute to the data available about the Indonesian mission movement, as well as to test the assumptions of the theological, biblical and praxeological work. The clear sense from this part of the research was that Indonesian agency leaders wanted to work with, not for, Western mission agencies, particularly in the areas of training and finance. In discussing the place of Western mission agencies in the sending of mission workers from the majority world, this study promotes a relational, rather than structural, answer to the debate. Western organisations must recognise the mission structures that are already in place in the majority world, namely local churches and their leaders. Consequently, the study concludes that any Western involvement in mission sending should be marked by mutuality, humility and shared learning, and must be exercised at the request of the national church to partner, not the desire of the Western organisation to grow.
Curricular Planning for Sociocultural Change and Development: A Critique
Creators: name: Zentner, Henry
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: Curricular planning for sociocultural development rests upon dubious ethnocentric assumptions respecting the superiority of the modern. Analysis shows that a society's capacity for controlling and directing its own inherent propensity for change and/or stability is profoundly conditioned by the phenomenological form experientially assumed by the basic epistemological categories of time, space, causation, number, ethics, and aesthetics. For a variety of logical and functional reasons, therefore, continuing validity must everywhere be accorded to many traditional practices.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 13 No 3 (1979)
The Construction of a Systematic Self Model
Creators: name: Massey-Hicks, M.
name: Altmann, H.
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: This paper is an attempt to proffer a self-theory model that exemplifies the percepts, constructs, and ideas contained in the current writing on the subject of the self. The model, the Systemic Self, has been formulated by eclectic reference to significant research and is presented as a schematic diagram that depicts a systematic arrangement of the psychological constructs and postulates of the self. The thrust of this endeavour is directed towards initiating a systematic and overall approach to the theory of self.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 13 No 3 (1979)
Accelerated Process Optimization for Laser-Based Additive Manufacturing by Leveraging Similar Prior Studies
Creators: name: Aboutaleb, Amir M
name: Linkan Bian
name: Elwany, Alaa
name: Shamsaei, Nima
name: Thompson, Scott M
name: Tapia, Gustavo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Manufacturing parts with target properties and quality in Laser-Based Additive Manufactured (LBAM) parts is crucial towards enhancing the “trustworthiness” of this emerging technology and pushing into the mainstream. Most of the existing LBAM studies do not use a systematic approach for optimizing process parameters (e.g., laser power, laser velocity, layer thickness, etc.) for desired part properties. We propose a novel process optimization method by directly utilizing experimental data from previous studies as the initial experimental data to guide the sequential optimization experiments of the current study. This serves to reduce the total number of time- and cost-intensive experiments needed. We verify our method and test its performance via comprehensive simulation studies that test various types of prior data. The results show that our method significantly reduces the number of optimization experiments, compared to conventional optimization methods. We also conduct a real-world case study that optimizes the relative density of parts manufactured using a Selective Laser Melting system. A combination of optimal process parameters is achieved within 5 experiments. Supplementary materials are available for this article. Go to the publisher's online edition of IIE Transaction for appendixes.
THE FORUM: A Section Devoted to Learned Opinion
Creators: name: Wagman, James
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: The American academic community is afflicted with a two-fold ideological blindness, affecting both its social position and its internal intellectual orie ntat ion. First, it has underestimated the role of market forces in determining the rewards and status of higher education, rationalizing its position in terms of social service and intellectual con­ tribution. Second, it has, through the "publish or perish" syndrome, unconsciously applied an essentially market view of intellectual motiva­ tion, ignoring the Social Darwinist and Taylorist origins of this view, and their relevance to the most onerous working-class jobs of early industrialism .
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 13 No 3 (1979)
An approach for analyzing and managing flexibility in engineering systems design based on decision rules and multistage stochastic programming
Creators: name: Michel-Alexandre Cardin
name: Qihui Xie
name: Ng, Tsan Sheng
name: Shuming Wang
name: Junfei Hu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: This article introduces an approach to assess the value and manage flexibility in engineering systems design based on decision rules and stochastic programming. The approach differs from standard Real Options Analysis (ROA) that relies on dynamic programming in that it parameterizes the decision variables used to design and manage the flexible system in operations. Decision rules are based on heuristic-triggering mechanisms that are used by Decision Makers (DMs) to determine when it is appropriate to exercise the flexibility. They can be treated similarly as, and combined with, physical design variables, and optimal values can be determined using multistage stochastic programming techniques. The proposed approach is applied as demonstration to the analysis of a flexible hybrid waste-to-energy system with two independent flexibility strategies under two independent uncertainty drivers in an urban environment subject to growing waste generation. Results show that the proposed approach recognizes the value of flexibility to a similar extent as the standard ROA. The form of the solution provides intuitive guidelines to DMs for exercising the flexibility in operations. The demonstration shows that the method is suitable to analyze complex systems and problems when multiple uncertainty sources and different flexibility strategies are considered simultaneously.
title: Apolline Divination at the Sanctuaries of Delphi, Claros and Didyma: A Cognitive Analysis
Creators: name: Frigerio, Giulia
Publisher: name: University of Kent
Year: 2022

description: In the past years, many interpretations of Apolline divination in ancient Greece attributed the behaviour of the oracle to hallucinogenic substances and to an altered state of mind. Scholars looked for chemical substances in the laurel branches the Pythia was probably chewing during the ritual, in the water of the sacred springs and in the sacred vapour emanating from the earth in Delphi. All these ideas have already been controverted following chemical analyses that did not find hallucinogenic substances in a quantity which is enough to alter the state of mind of the prophet and of the consultants in any of the places where Apolline divination was practised. Today, the questions remain open: what was actually going on during the process of divination? Why did the Greeks believe in the words of the prophet? Was the promantis sincere? I approach this issue from a cognitive perspective, that of the prophet/prophetess and that of the ancient oracle seekers by considering the cognitive stimuli that contributed to this experience. These cognitive stimulants led them to honestly believe that communication with the god did occur, during which Apollo truly revealed his wishes to mankind. These cognitive processes depend on the habitus and the neural activity. Specifically, three case-studies are analysed in this thesis. The sanctuary of Delphi is the main focus as the archetype of Apolline divination. Reaching its major popularity in the Classical period, its divinatory practices will be proved to be perfectly in line with the habitus of that time and with the biology of the human brain. As such, the oracular shrine did not need to implement the experience with artificial additions or chemical substances. Subsequently, the sanctuaries of Claros and Didyma are analysed under two different aspects. Reaching the top of their splendour in the Hellenistic and Imperial Ages, they are the heirs of Delphi in a different place and time. On one side, the aspect of the imitation of the most important centre for Apolline divination is observed, analysing the reasons behind the choice of borrowing several details from Delphi with a cognitive perspective. On the other side, the need for adapting the ritual to a new historical period with a different ontology is highlighted together with its consequences, such as the introduction of artificial inducement of cognitive processes to make everything more scenic and to actively engage human cognition and perception to a greater extent than previously. The research sheds new light on the interpretation and function of ancient divination which is nowadays still open. The chosen case studies can serve as the groundwork for a major contribution to the field: the introduction of a new methodology where the cognitive approach, which is already an innovative choice, is combined with a study of the habitus, which I believe is necessary for a correct interpretation of the archaeological evidence.
An Approach for Analyzing and Managing Flexibility in Engineering Systems Design Based on Decision Rules and Multistage Stochastic Programming
Creators: name: Michel-Alexandre Cardin
name: Qihui Xie
name: Ng, Adam Tsan Sheng
name: Shuming Wang
name: Junfei Hu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: This paper introduces an approach to assess the value and manage flexibility in engineering systems design based on decision rules and stochastic programming. The approach differs from standard real options analysis (ROA) relying on dynamic programming in that it parameterizes the decision variables used to design and manage the flexible system in operations. Decision rules are based on heuristics triggering mechanisms that are used by decision makers (DMs) to determine when it is appropriate to exercise the flexibility. They can be treated similarly as and combined with physical design variables, and optimal values can be determined using multistage stochastic programming techniques. The proposed approach is applied as demonstration to the analysis of a flexible hybrid waste-to-energy (WTE) system with two independent flexibility strategies under two independent uncertainty drivers in an urban environment subject to growing waste generation. Results show that the proposed approach recognizes the value of flexibility in a similar amount as standard ROA. The form of the solution provides intuitive guidelines to DMs for exercising the flexibility in operations. The demonstration shows that the method is suitable to analyze complex systems and problems, when multiple uncertainty sources and different flexibility strategies are considered simultaneously.
Journal of Educational Thought / Revue de la Pensée Educative, Vol 14 No 2 (1980)
Creators: name: Journal Of Educational Thought / Revue De La Pensée Educative
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: A Thank You Note...59-59 Writing and Re-writing the Canadian Educational Experience...60-63 A Review of Selected Materials in the Educational History of Western Canada: Opportunities for Further Research...64-79 Social Policy, 'Deviant' Children, and the Public Health Apparatus in British Columbia Between the Wars...80-91 Vocationalism and Its Promoters in British Columbia, 1900-1929...92-107 Temperance, Education and the WCTU in Alberta, 1905-1930...108-124 Better Schools Day in Saskatchewan and the Perils of Educational Reform...125-137 The Saskatchewan CCF: Education Policy and the Rejection of Socialism, 1942-1948...138-159 Charles Dickens : His Tragedy and Triumph...160-161 An Introduction to Nineteenth Century France...162-163
Bridging the gap: Assessing the effectiveness of rope bridges for wildlife in Singapore
Creators: name: Ow, Sebastian
name: Chan, Sharon
name: Toh, Yuet Hsin
name: Chan, Su Hooi
name: Lakshminarayanan, Jayasri
name: Jabbar, Sabrina
name: Ang, Andie
name: Loo, Adrian
Publisher: name: Brill Online
Year: 2022
Subjects: Other biological sciences not elsewhere classified

description: Roads that dissect natural habitats present risks to wildlife, creating gaps or barriers which animals have to traverse in order to move within and between their habitats. Restoring habitat connectivity can be achieved naturally by planting trees and vines to reconnect forest gaps, or artificially by creating culverts for small ground vertebrates, building overpasses for large terrestrial animals, or installing canopy bridges for arboreal fauna. The 3-km Old Upper Thomson Road borders the eastern side of the Central Catchment Nature Reserve, the largest nature reserve in Singapore, and isolates it from neighbouring forest patches. To facilitate safe crossing for tree-dwelling animals such as the critically endangered Raffles’ banded langurs (Presbytis femoralis) along Old Upper Thomson Road, two rope bridges were installed. We monitored the use of these rope bridges by vertebrates from April 2020 to August 2021 through surveillance cameras attached on one end of each bridge. A total of 64,118 videos were processed, with 6,218 (9.70%) containing vertebrates. Seven species, including three primates, two squirrels and two reptiles, utilised the bridges to travel between the forests. In particular, Raffles’ banded langurs made a total of 293 successful crossings. We have shown that these rope bridges are useful for arboreal species and can complement national efforts to restore connectivity in fragmented habitats.
A comparative study of three new conjugate gradient methods with exact line search
Creators: name: Hamoda, Mohamed
name: Mohd Rivaie
name: Abdelrhaman Abshar
name: Mamat, Mustafa
Publisher: name: figshare
Year: 2016
Subjects: subject: 10303 Optimisation
subject: FOS: Mathematics

description: Conjugate Gradient methods play an important role in solving unconstrained optimization, especially for large scale problems. In this paper, we compared the performance profile of the classical conjugate gradient coefficients FR, PRP with three new Bk . These three new Bk possess global convergence properties using the exact line search. Preliminary numerical results show that the three new Bk are very promising and efficient when compared to CG coefficients FR, PRP.
Journal of Educational Thought / Revue de la Pensée Educative, Vol 14 No 3 (1980)
Creators: name: Journal Of Educational Thought / Revue De La Pensée Educative
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: LUMINARIES and Luminaries...167-177 Economic Thought and Educational Policy-Making: An Historic Perspective...168-186 Zemecha - Assessing the Political and Social Foundations of Mass Education in Ethiopia...187-195 Formal Education in Israel: A Social Perspective...196-208 Sesame Street: The Packaging of a Curriculum...209-219 Liberal Education and Marketability...220-221 Education and Colonialism...222-222 Sociological Theories of Education...222-227 Shaping the Schools of the Canadian West...228-228 Tasks and Social Relations in Classrooms: A Study of Instructional Organization and its Consequences...229-229 Educational Futures: Anticipations by the Next Generation of Canadian Scholars...230-231 The Politics of Curriculum Change...231-232
Journal of Educational Thought / Revue de la Pensée Educative, Vol 15 No 1 (1981)
Creators: name: Journal Of Educational Thought / Revue De La Pensée Educative
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: Moral Education in the Schools...1-3 Moral Education Through the Development of the Moral Atmosphere of the School...4-19 A Critical Appraisal of the Educational and Psychological Perspectives on Moral Discussion...20-33 Moral Education in the Context of Lifelong Education...34-40 Moral Education, Moral Character, and the Virtues...41-46 Integrity Training: A Moral Code and Method for Moral Education...47-60 A Philosophy of Mind Adequate for Discourse on Morality: Iris Murdoch's Critique...61-72 Moral Education at the Logos Christian School and Education Society...73-74 A Critical Review of Yes Virginia , There is a Right and Wrong!...75-76 Essay Review - Reason to Believe...77-81 Open-Mindedness and Education...82-85
Journal of Educational Thought / Revue de la Pensée Educative, Vol 15 No 2 (1981)
Creators: name: Journal Of Educational Thought / Revue De La Pensée Educative
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: Are Educational Researchers Fair to The Classroom Teacher?...89-90 Creativity and the Standard's Question...91-101 Gestalt Workshops: Suggested In-Service Training for Teachers...102-112 Tutoring and Social Psychology...113-123 Giovanni Gentile: Mussolini 's Favorite Educational Philosopher...124-136 The Eq uality Question: Uncertainties in Educational Thought and Democratic Idealism...137-145 Classics in the Education of Girls and Women...146-147 The Forces Which Shaped Them: A History of the Education of Minority Groups and Children in British Columbia...148-149 McGill University: For the Advancement of Learn ing, Volume I, 180 1-1 895...150-151 Laboring Children: Briti sh Immigrant Apprentices to Canada, 1869-1924...152-154
Journal of Educational Thought / Revue de la Pensée Educative, Vol 15 No 3 (1981)
Creators: name: Journal Of Educational Thought / Revue De La Pensée Educative
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: Editorial...157-158 'Education For Commitment' A Logical Contradiction?...159-170 Faculty of Education and the Development of a Body of Knowledge of Teaching...171-186 Simon, Indoctrination and Ethical Relativism...187-194 Negative Student Attitudes and the Teaching of the Humanities...195-201 Schooling and Society in Twentieth Century British Columbia...202-208 Humanism: A Definition of Literacy...202-208
Journal of Educational Thought / Revue de la Pensée Educative, Vol 16 No 1 (1982)
Creators: name: Journal Of Educational Thought / Revue De La Pensée Educative
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: On the Study of Education...1-3 Must Educational Responsibility be an Illusion?...4-14 Wasted Resources: What Educational Philosophers Might Contribute to Educational Theory But Often Don't...15-22 Epistemic Authority, Institutional Power, and Curricular Knowledge...23-28 Values and the Ideal of Objectivity...29-34 Moral Education versus Values Clarification...35-41 Essay Review: The Marxist Theory of Schooling...42-46 American Education: The National Experience 1783-1876...47-48 Vergleichende Erziehungs Wissenchaft...49-51 Knowledge and Fallibilism: Essays on Improving Education...52-53 In the Children's Aid: J.J. Kelso and Child Welfare in Ontario...54-55 Creativity Across the Curriculum...56-58
Tubing modifications for countercurrent chromatography: Investigation of geometrical parameters
Creators: name: Englert, Michael
name: Vetter, Walter
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: Countercurrent chromatography (CCC) is a separation technique which may be described as a combination of a great number of liquid–liquid distributions of analytes in a two-phase solvent system with liquid chromatography (LC) features. Even optimized CCC separations currently provide a lower number of theoretical plates when compared to LC. For this reason, instrumental advancements are indispensable to, at least partly, overcome this drawback. Recently, we found that improvement of the classic CCC coil, that is using a long hollow tubing, may be achieved by the introduction of tubing crimpings which increase the stationary phase retention. In this study, we systematically investigated the effects of three geometrical parameters (crimping depth, distance between two crimpings as well as partial or complete crimping of the tubing) on the stationary phase retention by a factorial design of experiments approach. Separation efficiency tests were performed with two groups of analytes: fatty acid methyl esters (FAME) in the n-hexane/acetonitrile (HAcn) and alkyl p-hydroxybenzoates in the n-hexane/tert-butylmethylether/methanol/water solvent system. The most narrow crimping distance and the deepest crimping of the tubing were the best configurations in the examined flow rate range.
How High and Low Self-Empowered Teachers Work with Colleagues and School Principals
Creators: name: Wilson, Sandra Meacham
name: Coolican, M. Jean
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: This study explores the phenomena of teacher empowerment by describing intrinsic motivation associated with the tasks of working with colleagues and principals for two groups of teachers - those with a high and those with a low sense of self-empowerment. Data were collected via interviews that focused on goals and meanings teachers assigned to the tasks, their perceived competence in completing the tasks, and their self-determination in selecting behaviours to accomplish desired outcomes.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 30 No 2 (1996)
The Integration of Extrarational and Rational Learning Processes: Moving Towards the Whole Learner
Creators: name: Puk, Tom
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: The polemical debate between rationalists and nonrationalists need not occur. The paper briefly traces the evolution of information processing theory as it pertains to the emerging emphasis being placed on the psychological unconscious in classroom learning. Theory and practice are then synthesized, resulting in the development of a strategy which emphasizes extrarational learning processes (i.e., processes which occur at the unconscious level of the human mind) as well as a strategy which integrates rational and extrarational processes. It is felt that the selfdirected whole learner must and can be taught to make inner connections between these two levels of the human mind
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 30 No 2 (1996)
12 Jahre regionales Siedlungsflächen- Monitoring in Ostwürttemberg – (K)ein Erfolgsmodell?
Creators: name: Elgendy, Hany
name: Wilkens, Christina
Publisher: name: Zenodo
Year: 2024
Subjects: Monitoring
Flächenmanagement
Innenentwicklungspotenziale
Nachverdichtung
DFNS 2024

description: Nach 12 Jahren Siedlungsflächenmonitoring in Ostwürttemberg lautet ein erstes ernüch­terndes Fazit: Die Baulücken in der Region haben im Zeitraum von 2011 bis 2023 um 50 ha abgenommen, ein Minus von gerade mal 10 %. Aber waren die Kommunen wirklich so inaktiv? Ein Blick „hinter die Kulissen“ zeigt: Nein, waren sie nicht. Die Betrachtung der absoluten Zahlen ist irreführend, da sie nicht die tatsächliche Reduktion darstellt. Aussagekräftiger ist es, die Veränderung einzelner Flächen zu beleuchten: Welche Baulücke wurde seit 2011 bebaut, welche Außenreserve wurde zwischenzeitlich zunächst parzelliert und dann bebaut, welche neuen Baulücken sind hinzugekommen?

Die Basis dieser detaillierten räumlichen Auswertung bilden die seit 2011 alle drei Jahre stattfindenden Erhebungsgespräche mit allen Städten und Gemeinden der Region Ostwürttemberg nach einem einheitlichen Schema. Damit ist es möglich, die tatsächliche Mobilisierung von Baulücken, Innenentwicklungsflächen und Außenreserven je Gemeinde zu bilanzieren und zu quantitativen und qualitativen Merkmalen ins Verhältnis zu setzen. Dafür sollen ergänzend zur regionsweiten Flächenauswertung, zusammen mit 4 Modellkommunen aus der Region, Merkmale zur Bautätigkeit, Entwicklung der Einwohner- und Beschäftigten­zahlen, Entwicklung der Siedlungs- und Verkehrsfläche sowie örtliche Strategien der Innen­entwicklung (Flächenmanagement, Umnutzungen, Abriss – Neubau, Nachverdichtung) ver­tiefend ausgewertet werden und ins Verhältnis zur Mobilisierungstätigkeit gesetzt werden.

Der Beitrag stellt wesentliche Erkenntnisse aus den Flächenaktivitäten seit 2011 in der Region Ostwürttemberg dar sowie erste Ergebnisse aus der vertiefenden kommunalen Betrachtung.
Lysines in the tetramerization domain of p53 selectively modulate G1 arrest
Creators: name: Beckerman, Rachel
name: Yoh, Kathryn
name: Mattia-Sansobrino, Melissa
name: Zupnick, Andrew
name: Laptenko, Oleg
name: Karni-Schmidt, Orit
name: Jinwoo Ahn
name: In-Ja Byeon
name: Keezer, Susan
name: Prives, Carol
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Functional in a tetrameric state, the protein product of the p53 tumor suppressor gene confers its tumor-suppressive activity by transactivating genes which promote cell-cycle arrest, senescence, or programmed cell death. How p53 distinguishes between these divergent outcomes is still a matter of considerable interest. Here we discuss the impact of 2 mutations in the tetramerization domain that confer unique properties onto p53. By changing lysines 351 and 357 to arginine, thereby blocking all post-translational modifications of these residues, DNA binding and transcriptional regulation by p53 remain virtually unchanged. On the other hand, by changing these lysines to glutamine (2KQ-p53), thereby neutralizing their positive charge and potentially mimicking acetylation, p53 is impaired in the induction of cell cycle arrest and yet can still effectively induce cell death. Surprisingly, when 2KQ-p53 is expressed at high levels in H1299 cells, it can bind to and transactivate numerous p53 target genes including p21, but not others such as miR-34a and cyclin G1 to the same extent as wild-type p53. Our findings show that strong induction of p21 is not sufficient to block H1299 cells in G1, and imply that modification of one or both of the lysines within the tetramerization domain may serve as a mechanism to shunt p53 from inducing cell cycle arrest.
title: Cultures of the Chase: Authority, Community and Ritual in the Landscape of British Blood Sports, 1800-1914
Creators: name: Burton, Jonathan
Publisher: name: University of Kent
Year: 2022

description: Previous studies of British bloodsports have tended to focus solely on elite participants, examining how themes of class and ethnicity have affected the ways in which they visualised and conducted their chosen sports. This thesis takes a slightly different approach, choosing to chart the use of rituals within the cultures of a widely divergent set of blood sports communities across a period of one-hundred and fourteen years. During that time, both the social and the environmental landscapes evolved a good deal which duly shaped how many of these communities chose to represent themselves. However, the one constant was the theme of authority which these different communities were chasing. Across these different cultures, authority was a key part of sporting ritual, designed both to promote the community as a whole and the reputation of the personal protagonist. Whether it was enacted through the mechanisms of gender, class, culture or morality, appearing powerful and in control was what all blood sports enthusiasts desired, whatever their social background. Authority bound these communities together as well as exalting individuals, making them feel protected and accepted in an oft-changing world. Despite the different social demographics, moral standards and geographies over which they indulged in their sports, these feelings of community and authority was what drove them all and continued to inspire their love for the thrill of the chase.
The effect of anthracene on total dry matter and extracellular enzyme analysis of a starch-amended composting process
Creators: name: Sunday E. Elaigwu
name: Adams, John D. W.
name: G. M. Greenway
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology
subject: 60506 Virology

description: Composting technology has been widely used as a cost-effective, eco-friendly, and efficient solid waste management option for the bioremediation of organic pollutants. Most studies have focused on the use of compost in the bioremediation of organic pollutants, without any attention being paid to the effect of the organic pollutants on the composting process. Therefore, in this study, the effect of an organic pollutant (anthracene) on a starch-amended composting process is reported. In order to determine the effect, the total dry matter and the extracellular enzyme analysis (EEA) of starch-specific (α-glucosidase) and -nonspecific (β-glucosidase) substrates were monitored. Over the course of the experiments, there appeared to be some form of anthracene effect on the progression in the total dry matter and the extracellular enzyme analysis (EEA) of the α-glucosidase, particularly in the starch and anthracene–amended composts. The interactions between the starch and the anthracene consistently increased the total dry matter and the α-glucosidase activity of the starch and anthracene–amended composts. This observation is novel, and the kind of interaction is yet unknown. Therefore, detailed investigation to understand the magnitude of such interaction is necessary to potentially resolve these issues.
The effect of anthracene on total dry matter and extracellular enzyme analysis of a starch amended composting process
Creators: name: Sunday E. Elaigwu
name: Adams, John D.W.
name: G.M. Greenway
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: 60506 Virology

description: Composting technology has been widely used as a cost effective, eco-friendly, and efficient solid waste management option for the bioremediation of organic pollutants. Most studies have focused on the use of compost in the bioremediation of organic pollutants, without any attention being paid on the effect of the organic pollutants on the composting process. Therefore, in this study the effect of an organic pollutant (anthracene) on a starch amended composting process is reported. In order to determine the effect, the total dry matter and the extracellular enzyme analysis (EEA) of starch specific (α-glucosidase) and non-specific (β-glucosidase) substrate were monitored. Over the course of the experiments, there appeared to be some form of anthracene effect on the progression in the total dry matter and the extracellular enzyme analysis (EEA) of the α-glucosidase, particularly in the starch and anthracene amended composts. The interactions between the starch and the anthracene consistently increased the total dry matter and the α-glucosidase activity of the starch and anthracene amended composts. This observation is novel and the kind of interaction is yet unknown. Therefore, detailed investigation to know the magnitude of such interaction is necessary to potentially resolve these issues.
Le stage d'enseignement: Un milieu d'emancipation
Creators: name: Hebert, Huguette
name: Mandin, Lucille
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: This article examines how practice-teaching can become an opportunity for growth for student teachers. The authors situate their model of student teaching which facilitates reflective practice within their theory of teacher education. Reflection on their experiences with collaborative practiceteaching permits them to understand successful collaborative practiceteaching and how it becomes an opportunity for professional growth. This grounded knowledge assists them in their questioning of the reality of practice-teaching as it currently exists.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 30 No 2 (1996)