cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Experimental and numerical investigations of pull-out strength of timber joints with glued-in rods
Creators: name: Faghani, Pedram
Publisher: name: University of British Columbia
Year: 2013

description: Timber joints with glued-in rods have several advantages with respect to mechanical connections, such as higher stiffness, more uniform stress distribution, less bar corrosion problems and better appearance. This thesis describes experimental and numerical studies of timber joints made with glass fibre reinforced polymer (GFRP) rods glued by polyurethane adhesive (PUR) into glued-laminated timber specimens made of Douglas-fir. Experimental work was performed at Centre for Advanced Wood Processing of the Wood Science Department and the Materials Laboratory of the Civil Engineering Department at University of British Columbia Vancouver. A total of 125 specimens from 25 different test series with 5 replicates each were tested in tension until failure. The objective of the study was to evaluate the influence of the geometric parameters on the joint performance. The experimental data showed the importance of the rod diameter and anchorage length on the capacity of glued-in rod joints. In all the cases, when increasing the diameter of the bar or anchorage length, the average value of the reached failure load increased; this increase, however, was not linearly proportional to the timber-adhesive interface. Experimental failure loads have been compared with the theoretical values and in all the cases the experimental results were lower than the theoretical values, which might be because of incompatibilities between the chosen PUR and GRFP rod. A 3D finite element model was developed using the commercial software package ANSYS 14.0 in order to investigate the stress distribution within the joints. The model was validated and found to be in good agreement with the experimental observations, allowing it to be used for future parameter optimization and the application of numerical capacity prediction methods.
title: High rates of local control and low rates of symptomatic radionecrosis in patients treated with combination stereotactic radiosurgery and immunotherapy for melanoma brain metastases
Creators: name: Shanker, Mihir
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: CNS
subject: MR
subject: Radiation therapy / Oncology
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Stereotactic radiosurgery (SRS) demonstrates excellent local control for melanoma brain metastases (MBM) in the order of 75-95% [1-4]. This study aimed to assess toxicity and local control outcomes in patients receiving combined modality...
title: Non-traumatic Myositis Ossificans in the Obturator Internus muscle: case series and assessment of potential associated factors
Creators: name: Mistry, Vijay
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Musculoskeletal soft tissue
subject: CT
subject: MR
subject: PET-CT
subject: Comparative studies
subject: Calcifications / Calculi

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Purpose Myositis ossificans (MO) involves benign heterotopic calcification within muscle and soft tissues. There is a paucity of cases within the literature which describes MO involving the hip musculature. [1] We observed a group of patients who...
title: Convolutional Neural Networks: A Guide for Radiologists
Creators: name: Bhandari, Abhishta
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Computer applications
subject: Neural networks
subject: Computer Applications-Detection, diagnosis
subject: Education and training
subject: Outcomes
subject: Workforce

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To review convolutional neural networks (CNNs) as an example of machine learning. To review CNNs applications in...
Stellar Populations of Highly Magnified Lensed Galaxies: Young Starbursts at z~2
Creators: name: Wuyts, Eva
name: Rigby, Jane R.
name: Gladders, Michael D.
name: Gilbank, David G.
name: Sharon, Keren
name: Gralla, Megan B.
name: Bayliss, Matthew B.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a comprehensive analysis of the rest-frame UV to near-IR spectral energy distributions and rest-frame optical spectra of four of the brightest gravitationally lensed galaxies in the literature: RCSGA 032727-132609 at z=1.70, MS1512-cB58 at z=2.73, SGAS J152745.1+065219 at z=2.76 and SGAS J122651.3+215220 at z=2.92. This includes new Spitzer imaging for RCSGA0327 as well as new spectra, near-IR imaging and Spitzer imaging for SGAS1527 and SGAS1226. Lensing magnifications of 3-4 magnitudes allow a detailed study of the stellar populations and physical conditions. We compare star formation rates as measured from the SED fit, the H-alpha and [OII] emission lines, and the UV+IR bolometric luminosity where 24 micron photometry is available. The SFR estimate from the SED fit is consistently higher than the other indicators, which suggests that the Calzetti dust extinction law used in the SED fitting is too flat for young star-forming galaxies at z~2. Our analysis finds similar stellar population parameters for all four lensed galaxies: stellar masses 3-7*10^9 M_sun, young ages ~ 100 Myr, little dust content E(B-V)=0.10-0.25, and star formation rates around 20-100 M_sun/yr. Compared to typical values for the galaxy population at z~2, this suggests we are looking at newly formed, starbursting systems that have only recently started the build-up of stellar mass. These results constitute the first detailed, uniform analysis of a sample of the growing number of strongly lensed galaxies known at z~2.
description: 13 pages, 8 figures, Accepted to ApJ
title: A Convolutional Neural Network (CNN) approach to identify abnormal studies in a public CXR dataset
Creators: name: Kisby, Giles
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Artificial Intelligence
subject: Plain radiographic studies
subject: Computer Applications-General
subject: Image verification

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To use a Convolutional Neural Network (CNN) approach to identify abnormal studies in a public CXR...
title: Use of CT in Acute Aortic Syndrome
Creators: name: Kisby, Giles
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Arteries / Aorta
subject: CT
subject: Audit and standards
subject: Acute
subject: Aneurysms

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To determine the radiological detection rate of Acute Aortic Syndrome at the Emergency Departments of the Sunshine Coast Hospital and Health...
title: Endometriosis within the Inguinal Canal: A case report
Creators: name: Tan, Samantha
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Genital / Reproductive system female
subject: Pelvis
subject: CT
subject: Ultrasound
subject: Contrast agent-intravenous
subject: Cysts

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: Endometriosis is a disease characterised by ectopic endometrial stroma within extra-uterine sites. 1 These are typically found within the ovary, pelvic space, or attached to the uterine ligaments. 2 Inguinal endometriosis is characterised by the...
Nanoscale magnetic field mapping with a single spin scanning probe magnetometer
Creators: name: Rondin, L.
name: Tetienne, J. -P.
name: Spinicelli, P.
name: Savio, C. Dal
name: Karrai, K.
name: Dantelle, G.
name: Thiaville, A.
name: Rohart, S.
name: Roch, J. -F.
name: Jacques, V.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We demonstrate quantitative magnetic field mapping with nanoscale resolution, by applying a lock-in technique on the electron spin resonance frequency of a single nitrogen-vacancy defect placed at the apex of an atomic force microscope tip. In addition, we report an all-optical magnetic imaging technique which is sensitive to large off-axis magnetic fields, thus extending the operation range of diamond-based magnetometry. Both techniques are illustrated by using a magnetic hard disk as a test sample. Owing to the non-perturbing and quantitative nature of the magnetic probe, this work should open up numerous perspectives in nanomagnetism and spintronics.
title: Can we identify which patients with acute pulmonary embolism require intensive care support on imaging findings alone?
Creators: name: Tan, Samantha
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Pulmonary vessels
subject: CT
subject: CT-Angiography
subject: Computer Applications-Detection, diagnosis
subject: Embolism / Thrombosis

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Pulmonary embolism is a life-threatening disease that can be easily treated. 1 Most patients are successfully treated with oral anticoagulation without complications, however, a subgroup of patients require intensive care support and surgical...
Matter Density and Relativistic Models of Wave Function Collapse
Creators: name: Bedingham, Daniel
name: Duerr, Detlef
name: Ghirardi, GianCarlo
name: Goldstein, Sheldon
name: Tumulka, Roderich
name: Zanghi, Nino
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Mathematical models for the stochastic evolution of wave functions that combine the unitary evolution according to the Schroedinger equation and the collapse postulate of quantum theory are well understood for non-relativistic quantum mechanics. Recently, there has been progress in making these models relativistic. But even with a fully relativistic law for the wave function evolution, a problem with relativity remains: Different Lorentz frames may yield conflicting values for the matter density at a space-time point. We propose here a relativistic law for the matter density function. According to our proposal, the matter density function at a space-time point x is obtained from the wave function psi on the past light cone of x by setting the i-th particle position in |psi|^2 equal to x, integrating over the other particle positions, and averaging over i. We show that the predictions that follow from this proposal agree with all known experimental facts.
description: 6 pages LaTeX, 2 figures; v4: minor improvements
Rhagonycha Eschscholtz 1830
Creators: name: Yang, Yu-Xia
name: Yang, Xing-Ke
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cantharidae
Rhagonycha

description: Rhagonycha (s.str.) ulaensis Kazantsev, 1994
 MATERIAL. China: Inner Mongolia: Sugehe, 20.VI 1957, 1, 1 ; Xinjiang: Hejing, 2030m, 31.VII 1958, 1, leg. Chang-Qing Li.
DISTRIBUTION. China (new record): Inner Mongolia, Xinjiang; Mongolia, Russia (East Siberia), Japan (Kazantsev & Brancucci, 2007).
description: Published as part of Yang, Yu-Xia & Yang, Xing-Ke, 2013, Sixteen Species Of The Subfamily Cantharinae (Coleoptera, Cantharidae) New For The Fauna Of China, pp. 17-20 in Far Eastern Entomologist 256 on page 19, DOI: 10.5281/zenodo.10085015
High Multiplicity Searches at the LHC Using Jet Masses
Creators: name: Hook, Anson
name: Izaguirre, Eder
name: Lisanti, Mariangela
name: Wacker, Jay G.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: This article introduces a new class of searches for physics beyond the Standard Model that improves the sensitivity to signals with high jet multiplicity. The proposed searches gain access to high multiplicity signals by reclustering events into large-radius, or "fat," jets and by requiring that each event has multiple massive jets. This technique is applied to supersymmetric scenarios in which gluinos are pair-produced and then subsequently decay to final states with either moderate quantities of missing energy or final states without missing energy. In each of these scenarios, the use of jet mass improves the estimated reach in gluino mass by 20 % to 50 % over current LHC searches.
description: 9 pages, 6 figures; v3 corrects a few small typos
title: Finite temperature tensor network algorithm for frustrated two-dimensional quantum materials
Creators: name: Schmoll, Philipp
name: Balz, Christian
name: Lake, Bella
name: Eisert, Jens
name: Kshetrimayum, Augustine
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Frustrated magnetism
subject: Temperature
subject: Strongly correlated systems
subject: Tensor network methods
classificationCode: 539
subject: Moderne Physik

description: Aimed at a more realistic classical description of natural quantum systems, we present a two-dimensional tensor network algorithm to study finite temperature properties of frustrated model quantum systems and real quantum materials. For this purpose, we introduce the infinite projected entangled simplex operator ansatz to study thermodynamic properties. To obtain state-of-the-art benchmarking results, we explore the highly challenging spin-1/2 Heisenberg antiferromagnet on the Kagome lattice, a system for which we investigate the melting of the magnetization plateaus at finite magnetic field and temperature. Making a close connection to actual experimental data of real quantum materials, we go on to studying the finite temperature properties of Ca10⁢Cr7⁢O28. We compare the magnetization curve of this material in the presence of an external magnetic field at finite temperature with classically simulated data. As the first theoretical tool that incorporates both thermal fluctuations as well as quantum correlations in the study of this material, our work contributes to settling the existing controversy between the experimental data and previous theoretical works on the magnetization process.
title: Do we include the adjacent digit in finger x-rays?
Creators: name: Chan, Becky
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Musculoskeletal bone
subject: Musculoskeletal soft tissue
subject: Conventional radiography
subject: Audit and standards
subject: Acute
subject: Patterns of Care
subject: Quality assurance

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To illustrate a conventional finger series for paediatric patients To assess the inclusion of adjacent fingers on a paediatric finger series in Redcliffe...
Kambrium-Vendi töörühma välipäevik 13
Creators: name: Pirrus, Enn
name: Mens, Kaisa
Publisher: name: Tallinna Tehnikaülikooli Geoloogia Instituut
Year: 1967
Subjects: Cambrian and Vendian geological descriptions

description: Field notebook with descriptions of Cambrian and Vendian drill cores Estonia.
title: Quality of life in children and adolescents with alopecia areata—A systematic review
Creators: name: Prendke, Mona
name: Kanti‐Schmidt, Varvara
name: Wilborn, Doris
name: Hillmann, Kathrin
name: Singh, Rashmi
name: Vogt, Annika
name: Kottner, Jan
name: Blume‐Peytavi, Ulrike
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: alopecia areata (AA)
subject: children
subject: adolescents
subject: quality of life (QoL)
classificationCode: 610
subject: Medizin und Gesundheit

description: Alopecia areata (AA) is an autoimmune-mediated non-scarring hair loss whose stigmatizing effect may have a severe psychosocial impact. AA has been reported to be correlated with bullying, reduced quality of life (QoL) and psychiatric comorbidities. The effect of AA on QoL in adult patients has been systematically reviewed and found to be detrimental. No systematic evaluation of QoL in children with AA has been performed. The aim of this review is to systematically describe QoL in the child and adolescent population affected by AA. A systematic review of multiple databases and grey literature sources was conducted. Search terms included, but were not limited to, alopecia areata and quality of life. Only studies reporting results on health-related QoL in children and adolescents were included. We evaluated the studies regarding the risk of bias, and conceptual rigour concerning the quality of life and performed a descriptive synthesis of findings. Eight studies met the inclusion criteria, encompassing 358 participants with AA and 64 healthy peers. Seven studies were quantitative using four different standardized questionnaires and scores to measure QoL. One study used a qualitative design. All studies described impairment of children and adolescents' QoL by AA. The most consistently affected QoL domain was embarrassment and self-consciousness. Further psychosocial implications of AA included bullying and limiting participation in school or spare time activities. Existing evidence indicates a substantial impact of AA on QoL in children. In daily clinical practice as well as for developing new treatments QoL in paediatric AA plays a critical role. It should be considered a key outcome in clinical research and decision-making.
title: Can the presence of peritoneal free fluid predict the need for surgical management in patients with small bowel obstruction? - Retrospective audit
Creators: name: Chan, Becky
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Abdomen
subject: CT
subject: Audit and standards
subject: Acute
subject: Obstruction / Occlusion

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To evaluate the association between the radiological evidence of intraperitoneal free fluid and the need for surgical management in patients with SBO. To illustrate features of SBO on...
Rare cell separation using resettable cell traps
Creators: name: Beattie, William
Publisher: name: University of British Columbia
Year: 2013

description: Techniques for the separation of cells from heterogeneous samples that do not rely on biological labels are important in applications where specific labels are unknown or unavailable. However, limitations of existing label-free separation techniques have prevented their widespread adoption. Those techniques that separate based on cell size typically offer high throughput but lack specificity. Those that separate based on a combination of cell size and deformability have superior selectivity, but are slow and prone to clogging. This work reports a microfluidic device that employs novel resettable cell traps to separate cells based on size and deformability. The resettable cell trap is a microchannel with controllable cross-section, featuring recesses to temporarily store captured cells. Larger and less deformable cells flowing through a cell trap with constricted cross-section will be selectively captured due to size restriction, and can be released back into the flow for collection by enlarging the channel cross-section. Smaller and more deformable cells will simply pass through the constricted channel. The ability to enlarge the trap and purge it of captured cells enables long term operation without clogging. The cell separation device presented is able to separate UM-UC13 cancer cells from human leukocytes with high enrichment (~100x), retention (~90%) and throughput (450,000 cells/hour). Serial separation using this mechanism provides extremely high enrichment (~2500x) without sacrificing retention. The mechanism is also shown to resolve size differences of 1 µm between polystyrene microspheres. The resettable cell trap is an improvement upon existing technology, providing greater enrichment than possible through size-based techniques while improving throughput and eliminating problems caused by clogging that are typical of filtration based techniques.
title: CT-guided pudendal nerve perineural injection- a pictorial review
Creators: name: Chan, Becky
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Pelvis
subject: CT
subject: Treatment effects
subject: Pelvic floor dysfunction

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To describe pudendal nerve entrapment syndrome To describe the anatomy of the Alcock’s canal and the pudendal nerve To describe the techniques in CT-guided pudendal nerve perineural...
Stenothemus volaticus Champion 1925
Creators: name: Yang, Yu-Xia
name: Yang, Xing-Ke
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cantharidae
Stenothemus
Stenothemus volaticus

description: Stenothemus volaticus Champion, 1925
 MATERIAL. China: Xizang: Zhangmu, Youxiang, 3400m, 6.VII 1975, 1, 1, leg. Xue-Zhong Zhang; same data, 7.VII 1975, 1, leg. Fu-Sheng Huang; same data, 3300m, 6.VII 1975, 1.
DISTRIBUTION. China (new record): Xizang; India, Nepal (Kazantsev & Brancucci, 2007).
description: Published as part of Yang, Yu-Xia & Yang, Xing-Ke, 2013, Sixteen Species Of The Subfamily Cantharinae (Coleoptera, Cantharidae) New For The Fauna Of China, pp. 17-20 in Far Eastern Entomologist 256 on page 19, DOI: 10.5281/zenodo.10085015
title: Suture fixation of port-a-cath to prevent malposition: Is it necessary?
Creators: name: Chan, Becky
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Interventional vascular
subject: Fluoroscopy
subject: Audit and standards
subject: Venous access
subject: Blood
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To evaluate whether suture fixation of the Port-a-cath is correlated with a reduced incidence of port malposition. To describe the techniques in Port-a-cath...
Two-orbital quantum spin model of magnetism in the iron pnictides
Creators: name: Liu, C.
name: Yao, D. -X.
name: Sandvik, A. W.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study a two-orbital spin model to describe (pi,0) stripe antiferromagnetism in the iron pnictides. The "double-spin" model has an on-site Hunds's coupling and inter-site interactions extending to second neighbors (inter- and intra-orbital) on the square lattice. Using a variational method based on a cluster decomposition, we optimize wave functions with up to 8 cluster sites (up to 2^16 variational parameters). We focus on the anomalously small ordered moments in the stripe state of the pnictides. To account for it, and large variations among different compounds, we show that the second-neighbor cross-orbital exchange constant should be ferromagnetic, which leads to "partially hidden" stripe order, with a moment that can be varied over a large range by small changes in the coupling constants. In a different parameter region, we confirm the existence of a canted state previously found in spin-wave theory. We also identify several other phases of the model.
description: 8 pages, 7 figures. v2: significantly expanded
title: Assessing and improving timeliness of radiation delivery in regional radiotherapy centres
Creators: name: Jahromi, Nooshin
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Oncology
subject: Cone beam CT
subject: Radiation therapy / Oncology
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Based on good clinical practice, timely delivery of radiation therapy can be crucial. Good clinical practice also dictates that radical course of radiotherapy treatment should not be interrupted. Where interruptions are unavoidable, compensatory...
title: Comparison of inversion methods in MR elastography: An open-access pipeline for processing multifrequency shear-wave data and demonstration in a phantom, human kidneys, and brain
Creators: name: Meyer, Tom
name: Marticorena Garcia, Stephan
name: Tzschätzsch, Heiko
name: Herthum, Helge
name: Shahryari, Mehrgan
name: Stencel, Lisa
name: Braun, Jürgen
name: Kalra, Prateek
name: Kolipaka, Arunark
name: Sack, Ingolf
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: direct inversion
subject: local frequency estimation
subject: MRE
subject: multifrequency magnetic resonance elastography
subject: quantitative imaging biomarkers
subject: viscoelasticity
classificationCode: 610
subject: Medizin und Gesundheit

description: Purpose Magnetic resonance elastography (MRE) maps the viscoelastic properties of soft tissues for diagnostic purposes. However, different MRE inversion methods yield different results, which hinder comparison of values, standardization, and establishment of quantitative MRE markers. Here, we introduce an expandable, open-access, webserver-based platform that offers multiple inversion techniques for multifrequency, 3D MRE data. Methods The platform comprises a data repository and standard MRE inversion methods including local frequency estimation (LFE), direct-inversion based multifrequency dual elasto-visco (MDEV) inversion, and wavenumber-based (k-) MDEV. The use of the platform is demonstrated in phantom data and in vivo multifrequency MRE data of the kidneys and brains of healthy volunteers. Results Detailed maps of stiffness were generated by all inversion methods showing similar detail of anatomy. Specifically, the inner renal cortex had higher shear wave speed (SWS) than renal medulla and outer cortex without lateral differences. k-MDEV yielded higher SWS values than MDEV or LFE (full kidney/brain k-MDEV: 2.71 ± 0.19/1.45 ± 0.14 m/s, MDEV: 2.14 ± 0.16/0.99 ± 0.11 m/s, LFE: 2.12 ± 0.15/0.89 ± 0.06 m/s). Conclusion The freely accessible platform supports the comparison of MRE results obtained with different inversion methods, filter thresholds, or excitation frequencies, promoting reproducibility in MRE across community-developed methods.
title: Is the Nova StatSensor point of care system accurate in diagnosing renal impairment prior to IV contrast administration?
Creators: name: Mathur, Namit
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Contrast agents
subject: CT
subject: Audit and standards
subject: Contrast agent-intravenous
subject: Quality assurance

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To evaluate the efficacy of a POC device by comparison with the gold standard laboratory...
title: Transposon‐mediated glial cell line‐derived neurotrophic factor overexpression in human adipose tissue‐derived mesenchymal stromal cells: A potential approach for neuroregenerative medicine?
Creators: name: Rasińska, Justyna
name: Klein, Charlotte
name: Stahn, Laura
name: Maidhof, Felix
name: Pfeffer, Anna
name: Schreyer, Stefanie
name: Gossen, Manfred
name: Kurtz, Andreas
name: Steiner, Barbara
name: Hemmati‐Sadeghi, Shabnam
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: 6-hydroxydopamine (6-OHDA)
subject: adipose tissue-derived mesenchymal stromal cells (ASCs)
subject: glial cell line-derived neurotrophic factor (GDNF)
subject: microglia
subject: neuroinflammation
subject: Sleeping Beauty transposon
classificationCode: 610
subject: Medizin und Gesundheit

description: Glial cell line-derived neurotrophic factor (GDNF) has neuroprotective effects and may be a promising candidate for regenerative strategies focusing on neurodegenerative diseases. As GDNF cannot cross the blood-brain barrier to potentially regenerate damaged brain areas, continuous in situ delivery with host cells is desired. Here, a non-viral Sleeping Beauty transposon was used to achieve continuous in vitro overexpression of GDNF in immune-privileged human adipose tissue-derived mesenchymal stromal cells (GDNF-tASCs). In addition, in vivo survival, tolerance, and effectiveness of transfected cells were tested in a very mild 6-hydroxydopamine (6-OHDA)-induced dopamine depletion rat model by means of intrastriatal injection on a sample basis up to 6 months after treatment. GDNF-tASCs showed vast in vitro gene overexpression up to 13 weeks post-transfection. In vivo, GDNF was detectable 4 days following transplantation, but no longer after 1 month, although adipose tissue-derived mesenchymal stromal cells (ASCs) could be visualized histologically even after 6 months. Despite successful long-term in vitro GDNF overexpression and its in vivo detection shortly after cell transplantation, the 6-OHDA model was too mild to enable sufficient evaluation of in vivo disease improvement. Still, in vivo immunocompatibility could be further examined. ASCs initially induced a pronounced microglial accumulation at transplantation site, particularly prominent in GDNF-tASCs. However, 6-OHDA-induced pro-inflammatory immune response was attenuated by ASCs, although delayed in the GDNF-tASCs group. To further test the therapeutic potential of the generated GDNF-overexpressing cells in a disease-related context, a follow-up study using a more appropriate 6-OHDA model is needed.
Emergence of symmetries
Creators: name: Kirillov, A. A.
name: Korotkevich, A. A.
name: Rubin, S. G.
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The mechanism of symmetry formation is discussed in the framework of multidimensional gravity. It is shown that this process is strictly connected to the entropy decrease of compact space. The existence of low energy symmetries is not postulated from the beginning. They could be absent during the inflationary stage under certain conditions discussed in the paper.
description: 9 pages
title: Audit of Farm Property-Related Trauma in a Regional Queensland Referral Hospital
Creators: name: Tsang, Chi Lap Nicholas
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Trauma
subject: CT
subject: Outcomes analysis
subject: Trauma

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Rural trauma is associated with longer transportation distances and a higher risk of mortality (1, 2). This highlights the importance of timely access to medical care and medical imaging. This audit assessed and compared key performance indicators...
title: Effectiveness of a standardized skin care regimen to prevent atopic dermatitis in infants at risk for atopy: A randomized, pragmatic, parallel-group study
Creators: name: Kottner, Jan
name: Hillmann, Kathrin
name: Fastner, Alexandra
name: Conzade, Romy
name: Heidingsfelder, Stephanie
name: Neumann, Konrad
name: Blume‐Peytavi, Ulrike
name: ADAPI Study Group
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: skin care
subject: infants
subject: atopic dermatitis (AD)
classificationCode: 610
subject: Medizin und Gesundheit

description: Background It has been proposed that regular emollient application in early life could enhance skin barrier function and prevent atopic dermatitis (AD) especially in predisposed infants. This hypothesis was supported by evidence from exploratory and pilot trials showing protective effects in terms of reduced cumulative atopic dermatitis incidence with the use of daily emollient therapy starting immediately after birth. Objectives To investigate the effectiveness of a standardized skin care regimen for infants on the development of AD compared to not structured skin care regimen in infants with atopic predisposition. Methods Prospective, parallel group, randomized, pragmatic, investigator-blinded intervention trial including 160 infants with 52 weeks intervention and 52 weeks follow up phase up to the age of two years. Infants were randomly assigned to receive a standardized skin care regimen including once daily leave-on product application (lipid content 21%) or skin care as preferred by the parents. Results Using the intention to treat approach, the cumulative AD incidence was 10.6% after one year, and 19.5% after two years in the total sample. There were no statistical significant differences between intervention and control groups. Skin barrier parameters between the intervention and control groups were comparable. AD severity was higher and quality of life was more affected in the control group. Conclusions Regular emollient application during the first year of life does not prevent the development of atopic dermatitis. A standardized skin care regimen does not delay skin barrier development or causes side effects.
NLL+NNLO predictions for jet-veto efficiencies in Higgs-boson and Drell-Yan production
Creators: name: Banfi, Andrea
name: Salam, Gavin P.
name: Zanderighi, Giulia
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Using the technology of the CAESAR approach to resummation, we examine the jet-veto efficiency in Higgs-boson and Drell-Yan production at hadron colliders and show that at next-to-leading logarithmic (NLL) accuracy the resummation reduces to just a Sudakov form factor. Matching with NNLO calculations results in stable predictions for the case of Drell-Yan production, but reveals substantial uncertainties in gluon-fusion Higgs production, connected in part with the poor behaviour of the perturbative series for the total cross section. We compare our results to those from POWHEG with and without reweighting by HqT, as used experimentally, and observe acceptable agreement. In an appendix we derive the part of the NNLL resummation corrections associated with the radius dependence of the jet algorithm.
description: 30 pages, 8 figures; v2 as published in JHEP
title: Spectrum of imaging findings on the 2019 Novel Coronavirus Disease (COVID-19): A Literature Review
Creators: name: Afaghi, Mahsa
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Lung
subject: CT
subject: Health policy and practice
subject: Infection

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Since December 2019, a new respiratory disease known as SARS-CoV-2, developed in China and rapidly spread to other countries. It was declared a pandemic by March 2020, and the name for the new coronavirus disease was changed to COVID-19. In patients...
Pricing Financial Derivatives Subject to Counterparty Risk and Credit Value Adjustment
Creators: name: White, Alan
Publisher: name: Zenodo
Year: 2019
Subjects: credit value adjustment (CVA), credit risk modeling, financial derivative valuation, collateralization, margin and netting.

description: This article presents a generic model for pricing financial derivatives subject to counterparty credit risk. Both unilateral and bilateral types of credit risks are considered. Our study shows that credit risk should be modeled as American style options in most cases, which require a backward induction valuation. To correct a common mistake in the literature, we emphasize that the market value of a defaultable derivative is actually a risky value rather than a risk-free value. Credit value adjustment (CVA) is also elaborated. A practical framework is developed for pricing defaultable derivatives and calculating their CVAs at a portfolio level.
title: Robust methylation‐based classification of brain tumours using nanopore sequencing
Creators: name: Kuschel, Luis P.
name: Hench, Jürgen
name: Frank, Stephan
name: Hench, Ivana Bratic
name: Girard, Elodie
name: Blanluet, Maud
name: Masliah‐Planchon, Julien
name: Misch, Martin
name: Onken, Julia
name: Czabanka, Marcus
name: Yuan, Dongsheng
name: Lukassen, Sören
name: Karau, Philipp
name: Ishaque, Naveed
name: Hain, Elisabeth G.
name: Heppner, Frank
name: Idbaih, Ahmed
name: Behr, Nikolaus
name: Harms, Christoph
name: Capper, David
name: Euskirchen, Philipp
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: brain tumour
subject: epigenomics
subject: machine learning
subject: molecular pathology
subject: nanopore sequencing
subject: whole-genome sequencing
classificationCode: 610
subject: Medizin und Gesundheit

description: Background DNA methylation-based classification of cancer provides a comprehensive molecular approach to diagnose tumours. In fact, DNA methylation profiling of human brain tumours already profoundly impacts clinical neuro-oncology. However, current implementation using hybridisation microarrays is time consuming and costly. We recently reported on shallow nanopore whole-genome sequencing for rapid and cost-effective generation of genome-wide 5-methylcytosine profiles as input to supervised classification. Here, we demonstrate that this approach allows us to discriminate a wide spectrum of primary brain tumours. Results Using public reference data of 82 distinct tumour entities, we performed nanopore genome sequencing on 382 tissue samples covering 46 brain tumour (sub)types. Using bootstrap sampling in a cohort of 55 cases, we found that a minimum set of 1000 random CpG features is sufficient for high-confidence classification by ad hoc random forests. We implemented score recalibration as a confidence measure for interpretation in a clinical context and empirically determined a platform-specific threshold in a randomly sampled discovery cohort (N = 185). Applying this cut-off to an independent validation series (n = 184) yielded 148 classifiable cases (sensitivity 80.4%) and demonstrated 100% specificity. Cross-lab validation demonstrated robustness with concordant results across four laboratories in 10/11 (90.9%) cases. In a prospective benchmarking (N = 15), the median time to results was 21.1 h. Conclusions In conclusion, nanopore sequencing allows robust and rapid methylation-based classification across the full spectrum of brain tumours. Platform-specific confidence scores facilitate clinical implementation for which prospective evaluation is warranted and ongoing.
Complex Heavy-Quark Potential at Finite Temperature from Lattice QCD
Creators: name: Rothkopf, Alexander
name: Hatsuda, Tetsuo
name: Sasaki, Shoichi
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We calculate for the first time the complex potential between a heavy quark and antiquark at finite temperature across the deconfinement transition in lattice QCD. The real and imaginary part of the potential at each separation distance $r$ is obtained from the spectral function of the thermal Wilson loop. We confirm the existence of an imaginary part above the critical temperature $T_C$, which grows as a function of $r$ and underscores the importance of collisions with the gluonic environment for the melting of heavy quarkonia in the quark-gluon-plasma.
description: 4 pages, 3 figures, to be published in PRL
title: Artificial Intelligence in 2021 and beyond: A primer for Radiologists
Creators: name: Gray, Phillippa
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Artificial Intelligence
subject: CT
subject: MR
subject: PET
subject: Education
subject: Technology assessment
subject: Education and training

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: Learning Objectives The reader will be able to: Understand the basic concepts of artificial intelligence; Read and talk about topics surrounding artificial intelligence using consistent and accepted definitions of basic terminology; Obtain an...
Fermionization of two distinguishable fermions
Creators: name: Zürn, G.
name: Serwane, F.
name: Lompe, T.
name: Wenz, A. N.
name: Ries, M. G.
name: Bohn, J. E.
name: Jochim, S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: In this work we study a system of two distinguishable fermions in a 1D harmonic potential. This system has the exceptional property that there is an analytic solution for arbitrary values of the interparticle interaction. We tune the interaction strength via a magnetic offset field and compare the measured properties of the system to the theoretical prediction. At the point where the interaction strength diverges, the energy and square of the wave function for two distinguishable particles are the same as for a system of two identical fermions. This is referred to as fermionization. We have observed this phenomenon by directly comparing two distinguishable fermions with diverging interaction strength with two identical fermions in the same potential. We observe good agreement between experiment and theory. By adding one or more particles our system can be used as a quantum simulator for more complex few-body systems where no theoretical solution is available.
title: Air Trapping: A review of imaging technique and findings with an overview of small airways diseases- A Pictorial Essay
Creators: name: Tan, Samantha
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Lung
subject: CT-High Resolution
subject: Education
subject: Education and training

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: Air trapping is a common finding when reviewing CT scans of the thorax, and is widely accepted as an indirect sign of small airways disease. In this pictorial essay, we describe the approach to assessing air trapping on CT and describe the...
Walteriella coccinea
Creators: name: Yang, Yu-Xia
name: Yang, Xing-Ke
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cantharidae
Walteriella
Walteriella coccinea

description: Walteriella coccinea (Champion, 1926)
 MATERIAL. China: Yunnan: Gengma, 5.V 1956, 1, leg. HUANG Tianrong; Menglongbanna, Mengsong, 1600m, 26.IV 1958, 2, leg. Shu-Yong Wang.
DISTRIBUTION. China (new record): Yunnan; Burma (Kazantsev, 1999).
description: Published as part of Yang, Yu-Xia & Yang, Xing-Ke, 2013, Sixteen Species Of The Subfamily Cantharinae (Coleoptera, Cantharidae) New For The Fauna Of China, pp. 17-20 in Far Eastern Entomologist 256 on page 19, DOI: 10.5281/zenodo.10085015
Shear flow of non-Brownian suspensions close to jamming
Creators: name: Andreotti, Bruno
name: Barrat, Jean-Louis
name: Heussinger, Claus
Publisher: name: arXiv
Year: 2011
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The dynamical mechanisms controlling the rheology of dense suspensions close to jamming are investigated numerically, using simplified models for the relevant dissipative forces. We show that the velocity fluctuations control the dissipation rate and therefore the effective viscosity of the suspension. These fluctuations are similar in quasi-static simulations and for finite strain rate calculations with various damping schemes. We conclude that the statistical properties of grain trajectories -- in particular the critical exponent of velocity fluctuations with respect to volume fraction ϕ-- only weakly depend on the dissipation mechanism. Rather they are determined by steric effects, which are the main driving forces in the quasistatic simulations. The critical exponent of the suspension viscosity with respect to ϕcan then be deduced, and is consistent with experimental data.
Pricing Credit Default Swap Subject to Counterparty Risk and Collateralization
Creators: name: White, Alan
Publisher: name: Zenodo
Year: 2019
Subjects: valuation model; credit risk modeling; collateralization; correlation, CDS.

description: This article presents a new model for valuing a credit default swap (CDS) contract that is affected by multiple credit risks of the buyer, seller and reference entity. We show that default dependency has a significant impact on asset pricing. In fact, correlated default risk is one of the most pervasive threats in financial markets. We also show that a fully collateralized CDS is not equivalent to a risk-free one. In other words, full collateralization cannot eliminate counterparty risk completely in the CDS market.
title: Acute diverticulitis imaging scoring systems: A pictorial review.
Creators: name: McGill, Jeannette
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2021
Subjects: subject: Abdomen
subject: CT
subject: Surgery
subject: Diverticula

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: 1) Review of imaging findings of common and uncommon complications of acute diverticulitis 2) Review and comparison of acute diverticulitis imaging scoring...