cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Revue bibliographique menée par analyse de texte : application aux transferts de chaleur et d'humidité dans une paroi poreuse biosourcée
Creators: name: Billaud, Yann
name: Moreau, Florian
name: Milhet, Xavier
name: Saury, Didier
Publisher: name: Société Française de Thermique
Year: 2024
Subjects: Paroi poreuse biosourcée
Transferts de chaleur
Transferts d'humidité

description: Après une introduction sur les enjeux liés à la performance énergétique des bâtiments, la notion d'énergie grise est discutée pour mettre en perspective la réglementation actuelle et déplorer la non prise en compte de la durée de vie des éléments de paroi. Un bref aperçu de l'évolution des techniques constructives couplée à des données relatives aux habitations principales issues du recensement permet d'identifier à la fois la proportion et la nature du bâti ancien dans le parc actuel. Les spécificités des matériaux constituants les maisons anciennes sont ensuite discutées, de même que leurs incompatibilités avec les techniques et matériaux d'isolation actuels, plus particulièrement vis-à-vis des transferts d'humidité dans les parois indispensables à la pérennité des ouvrages. Après un aperçu de l'ensemble des dispositifs mis en place pour limiter la consommation énergétique dans le secteur du bâtiment, des études mettant en doute l'efficacité de la politique de rénovation énergétique des 30 dernières années sont discutées. Ces études s'accordent sur l'importance de la prise en compte de l'énergie grise pour établir une stratégie efficace afin de relever le défi des enjeux énergétiques et climatiques, et de fait, l'importance de la durée de vie des bâtiments. Cette partie introductive se termine en mettant en avant l'intérêt porté aux parois biosourcées et plus particulièrement celles à base de chaux-chanvre. La partie suivante discute des performances thermiques imposées par la réglementation environnementale en évoquant les critères qui ne sont pas pris en compte. Cette réflexion soulève la nécessité d'effectuer une étude bibliographique approfondie dans le but d'identifier l'ensemble des éléments à prendre en compte pour être capable de juger de la pertinence de cette technique constructive, notamment pour une application à grande échelle. Pour cela une méthodologie de recherche bibliographique est proposée. Celle-ci repose sur l'utilisation d'outils de fouille de texte et de données appliqués sur des corpus d'articles téléchargés depuis une base de données. Les résultats sont analysés et commentés pour servir de base à l'élaboration d'un projet de recherche.
On a bivariate generalized gamma distribution
Creators: name: Bologna, S.
Publisher: name: Dep. of Statistical Sciences "Paolo Fortunati", Università di Bologna
Year: 2013

description: A bivariate generalized gamma distribution (with marginal distributions of a gamma generalized type) is obtained from a bivariate normal distribution by means of a transformation. The analytic form of the joint density function presents symmetry between the marginal variables and a single non linear correlation parameter. Marginal and conditional densities distributions are obtained at first and, next, the expression of the moments. The estimation of the parameters is briefly dealt too.
description: Statistica; Vol 47, No 4 (1987)
Modeling and Analysis of Aluminum Bumpers for Automobiles
Creators: name: Soundararajan R, Krishnakanth S, Sugan V
Publisher: name: Zenodo
Year: 2024

description: An automobile's bumper is a vital part that helps absorb impact energy and reduces damage to the vehicle's front end components, including the intercooler, radiator, and hoses connecting them. This increases safety and lowers unintentional damage costs. Because the government is prohibiting the use of additional bumpers on the front side of vehicles to ensure the proper functioning of the airbag systems, we have found ourselves in a situation where modeling and the use of the material for the bumper have been upgraded with improvements in the design and use of various composite quality materials to make the bumper of a passenger car. Since the front of the car absorbs the most of the impact force in most passenger car accidents, the bumper and other parts of the car are also damaged. Proper selection of material and design of the bumper play an important role in the safety of vehicle passengers and components and the need to release the radiator temperature for engine safety. The automobile industry places a high priority on safety, especially while designing and testing car bumpers. Using Solid Works 2022, this project replicates a crash test for automobile bumpers composed of Nylon 101 and Aluminum 1060 alloy. The bumpers are tested by slamming them into a wall at 50 meters per second. They weigh 1.8 kg (nylon) and have densities of 1150 kg/m³ (nylon) and 2700 kg/m³ (aluminum). The simulation collects findings in less than 30 µs and has a high-quality mesh with around 116,000 components. The purpose of this study is to compare these materials' performances in order to gain knowledge for future vehicle design.
Cultural Variation in Children's Development of Executive Function
Creators: name: Ayala, Perla
Publisher: name: Zenodo
Year: 2024
Subjects: executive function
culture
children
development
indigenous

description: Executive Function skills (EFs) are cognition-related abilities that support children in  goal-directed behaviors, essential for their growth in areas like learning (Obradovic et al., 2018). This study explored cultural variations in children's performance on EF tasks by focusing on standardized EF tasks vs. non-traditional EF tasks. Yucatec Maya (YM) children (N = 10) and middle-class U.S.A. children (N = 11) participated in the study. We predicted that children from the US would perform better in traditional EF tasks, and YM children would perform better in culturally responsive EF tasks. We conducted a preliminary analysis of six participants' performance in two EF tasks, including The Tower of Hanoi and a non-traditional culturally responsive task requiring attention to two events (sorting nuts and bolts while attending to a filling bucket) simultaneously. The results were that US children performed better on the traditional Tower of Hanoi task but less well on the nontraditional task.  The outcome suggests limitations of previous studies that predominantly used traditional tasks to study EF skills of Maya children. Future studies should examine how Maya children perform better than U.S.A. children in culturally responsive tasks than traditional tasks.
Eustrophopsis crowdyi Pollock 2012
Creators: name: Johnston, M. Andrew
name: Warner, William B.
name: Pollock, Darren A.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Tetratomidae
Eustrophopsis
Eustrophopsis crowdyi

description: Eustrophopsis crowdyi Pollock, 2012
 Eustrophopsis crowdyi Pollock 2012: 39.
Literature Records: Apache, Cochise counties (Pollock 2012).
Specimens Examined: None beyond those cited above.
description: Published as part of Johnston, M. Andrew, Warner, William B. & Pollock, Darren A., 2024, New Records and a Checklist of Melandryidae and Tetratomidae Known from Arizona, USA (Coleoptera: Tenebrionoidea), pp. 53-60 in The Coleopterists Bulletin 78 (1) on page 57, DOI: 10.1649/0010-065X-78.1.53, http://zenodo.org/record/13243675
Effect of mosquito saliva from distinct species on human dermal endothelial cell function in vitro and West Nile virus pathogenesis in vivo
Creators: name: Visser, Imke
name: Vaes, Vincent
name: van Run, Peter
name: Marshall, Eleanor M.
name: Vermaat, Lars
name: Linthout, Charlotte
name: Dekkers, Dick H.W.
name: Demmers, Jeroen A.A.
name: Koopmans, Marion P.G.
name: Koenraadt, Constantianus J.M.
name: Rissmann, Melanie
name: Rockx, Barry
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: During probing and feeding, an infected mosquito injects both virus and saliva into the host skin. The presence of mosquito saliva in the skin increases arbovirus pathogenesis in the bitten host, however the exact mechanism behind this remains to be determined. It is hypothesized that disease enhancement is dependent on the function of the dermal endothelium, where increased permeability aids in the influx of virus-susceptible cells to the bite site and therefore more cells for the virus to replicate in. Here, we investigate the effects of saliva from Culex and Aedes species on human dermal endothelial cell function in vitro. Furthermore, we investigate the effect of Culex saliva on West Nile virus (WNV) pathogenesis in a mouse model. We found that salivary gland extract from anthropophilic mosquito species (Aedes and Cx. pipiens molestus) induce permeability of the human dermal endothelium, while an ornithophilic mosquito species (Cx. pipiens pipiens) does not. We identified that this effect is likely due to the presence of protease(s) in Cx. pipiens molestus saliva that are absent in Cx. pipiens pipiens saliva. In addition, we show that presence of Culex saliva at the WNV inoculation site in vivo leads to more consistent weight loss, increased permeability of the dermal endothelium at the inoculation site, and increased mortality compared to inoculation of WNV alone. Identification and characterization of novel salivary proteins from similar but genetically distinct mosquito species will advance the development of intervention methods to combat potential transmission risks and disease severity of emerging mosquito-borne pathogens.
Linear econometric models in a limited information framework
Creators: name: Cappuccio, N.
Publisher: name: Dep. of Statistical Sciences "Paolo Fortunati", Università di Bologna
Year: 2013

description: A simultaneous econometric model is named as incomplete when the number of the structural equations is less than the number of the endogenous variables. One usual way to make this type of model statistically tractable is that of adding an adequate number of equations in unconstrained reduced form in such a way to "complete" it. In this paper the statistical bases of this type of models are analysed. In particular the hypotheses, implicit to their text-book formulation, are carefully examined. Following Engle, Hendry and Richard (1983), the structural equations are defined as a set of linear constraints on the vector of the means of a given multivariate conditional distribution. As in Florens, Mouchart and Richard (1979), three forms of the model are considered the abstract one, the implicit one and the explicit one. By emphasizing the choice of the model parametrization, the treatment of the incidental parameters present in the model is studied. In particular the use either of the erogeneity assumptions for their elimination or of the instrumental variables for their modelisation is carefully examined.
description: Statistica; Vol 47, No 4 (1987)
Characterizing the growing population of patients hospitalized with methamphetamine-associated heart failure at two hospitals in Oregon
Creators: name: Hiatt, Shirin
name: Camacho, S.A.
name: Lee, C.S.
name: Dieckmann, N.
name: Macon, C.
name: Shalen, E.
name: Robles, Y.
name: Mitchell, J.
name: Habecker, B.
name: Denfeld, Q.E.
Publisher: name: Oregon Health and Science University
Year: 2024
Subjects: subject: Heart failure
subject: Methamphetamine
subject: Substance-Related Disorders
subject: Amphetamine-Related Disorders
subject: Mechanotransduction, Cellular
subject: Oregon
subject: methamphetamine-associated heart failure
subject: hospitalized patients
subject: substance-use

description: Methamphetamine-associated heart failure (MethHF) is quickly becoming a recognized healthcare problem with devastating patient and societal impact, especially in the state of Oregon, which has the highest rate of methamphetamine abuse in the US. However, our understanding of this phenomenon is very limited. We aimed to describe the sociodemographic and clinical characteristics of patients hospitalized with MethHF as compared with patients hospitalized with HF but not using methamphetamine.
Comparative proteomic studies of cell membrane proteins in three cells with different susceptibility to SARS-COV-2 virus infection
Creators: name: Shen, Liming
name: Zhuang, Hongbin
name: Lin, Jing
name: Cao, Xueshan
name: Tang, Xiaoxiao
name: Zhang, Huajie
name: Khan, Naseer Ullah
name: zhang, jun
name: Feng, Yuying
Publisher: name: figshare
Year: 2022
Subjects: Cell Biology

description: We used a kit to extract cell membrane proteins from each type of cell. Because the maximum label of iTRAQ are eight, the biological replicates were set in HAEC and Huh7 cell and two biological replicates were set in Vero E6 cell. The t-test was used to identify DEPs. The resulting p values from both tests were adjusted to control for multiple testing using the Benjamini–Hochberg correction. Significance was set at p < 0.05.
Asymptotic sampling distribution of concentration indices: a parametric approach
Creators: name: Latorre, G.
Publisher: name: Dep. of Statistical Sciences "Paolo Fortunati", Università di Bologna
Year: 2013

description: The objective of this work is to find the limiting sample distribution of three inequality measures assuming either Pareto or Log-normal distribution of income in the population. The method for obtaining such limiting distribution consists in deriving the maximum likelihood estimators of the parameters of the Pareto and Log-normal distribution. Then the limiting distribution are obtained by considering the general property of the asymptotic normality enjoyed by the maximum likelihood estimators.
description: Statistica; Vol 47, No 4 (1987)
Dissipation in oscillating water columns
Creators: name: Hasan, Md Kamrul
Publisher: name: Swinburne
Year: 2024

description: The Oscillating Water Column (OWC), regarded as the first generation Wave Energy Converter (WEC), is one of the most effective technologies for extraction of ocean wave energy. Most OWCs are designed to resonate at incoming wave frequencies, so that efficiency of the device would be the maximum. However, the damping factors, which control the actual value of this maximum, are not clearly identified and modelled. Therefore, an extensive study of the internal fluid dynamics of an OWC is carried out to identify those damping factors, and furthermore, to estimate the amount of energy loss due to their presence in OWCs.
Eustrophopsis indistinctus
Creators: name: Johnston, M. Andrew
name: Warner, William B.
name: Pollock, Darren A.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Tetratomidae
Eustrophopsis
Eustrophopsis indistinctus

description: Eustrophopsis indistinctus (LeConte, 1851)
 Eustrophus indistinctus LeConte 1851: 151.
Literature Records: Cochise, Gila, Graham, Greenlee, Maricopa, Pima, Pinal, Santa Cruz, Yavapai counties (Pollock 2012).
Specimens Examined:ASUHIC (Gila, Maricopa, Pima, Santa Cruz counties).
description: Published as part of Johnston, M. Andrew, Warner, William B. & Pollock, Darren A., 2024, New Records and a Checklist of Melandryidae and Tetratomidae Known from Arizona, USA (Coleoptera: Tenebrionoidea), pp. 53-60 in The Coleopterists Bulletin 78 (1) on page 57, DOI: 10.1649/0010-065X-78.1.53, http://zenodo.org/record/13243675
Dependence structures f normal observations and distributions of one-way ANOVA statistics
Creators: name: Baldessari, B.
name: Tranquilli, G. B.
Publisher: name: Dep. of Statistical Sciences "Paolo Fortunati", Università di Bologna
Year: 2013

description: Si stabiliscono condizioni necessarie e sufficienti sulla matrice di covarianze di un insieme di variabili casuali dipendenti affinché il numeratore ed il denominatore della statistica F ,relativa ad una analisi campionaria della varianza ad un solo fattore, soddisfino le corrispondenti combinazioni delle seguenti condizioni
(i) il numeratore ed il denominatore sono indipendenti;
(ii) il denominatore è distribuito come una variabile casuale proporzionale ad un chi quadrato;
(iii) il numeratore è distribuito come una variabile casuale proporzionale ad un chi quadrato.
Queste condizioni sono espresse anche esplicitamente in termini di covarianze delle osservazioni e delle medie dei gruppi. Vengono considerate anche connessioni con alcuni risultati noti ed è presentato un riassunto della letteratura sull'argomento.
description: Statistica; Vol 47, No 4 (1987)
Enhanced variant neutralisation through glycan masking of SARS-CoV-2 XBB1.5 RBD
Creators: name: Olivier, Joey
name: George, Charlotte
name: Huang, Chloe Qingzhou
name: Sujit, Sneha B.
name: Tonks, Paul
name: Cantoni, Diego
name: Grove, Joe
name: O’Reilly, Laura
name: Geiger, Johannes
name: Dohmen, Christian
name: Mummert, Verena
name: Samuel, Anne Rosalind
name: Plank, Christian
name: Kinsley, Rebecca
name: Temperton, Nigel
name: Pfranger, Martina
name: Wagner, Ralf
name: Heeney, Jonathan L
name: Vishwanath, Sneha
name: Carnell, George W.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Enhanced variant neutralisation through glycan masking of SARS-CoV-2 XBB1.5 RBD
The Place and Value of Sodium-Glucose Cotransporter 2 Inhibitors in the Evolving Treatment Paradigm for Type 2 Diabetes Mellitus: A Narrative Review.
Creators: name: Wilding, John PH
name: Evans, Marc
name: Fernando, Kevin
name: Gorriz, Jose Luis
name: Cebrian, Ana
name: Diggle, Jane
name: Hicks, Debbie
name: James, June
name: Newland-Jones, Philip
name: Ali, Amar
name: Bain, Stephen
name: Da Porto, Andrea
name: Patel, Dipesh
name: Viljoen, Adie
name: Wheeler, David C
name: Del Prato, Stefano
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Type 2 diabetes mellitus
Cardiovascular disease
Heart Failure
Chronic Kidney Disease
Cardiovascular Risk
Sglt2 Inhibitors
Diabetic Kidney Disease
Oral Glucose-lowering Medicines
Prescribing Tools
Cardiorenal Protection

description: Funder: Mundipharma Research Limited
description: Over recent years, the expanding evidence base for sodium-glucose cotransporter-2 inhibitor (SGLT2i) therapies has revealed benefits beyond their glucose-lowering efficacy in the treatment of Type 2 diabetes mellitus (T2DM), resulting in their recognition as cardiorenal medicines. While SGLT2is continue to be recommended among the second-line therapies for the treatment of hyperglycaemia, their true value now extends to the prevention of debilitating and costly cardiovascular and renal events for high-risk individuals, with particular benefit shown in reducing major adverse cardiac events and heart failure (HF) and slowing the progression of chronic kidney disease. However, SGLT2i usage is still suboptimal among groups considered to be at greatest risk of cardiorenal complications. The ongoing coronavirus disease 2019 (COVID-19) pandemic has intensified financial pressures on healthcare systems, which may hamper further investment in newer effective medicines. Emerging evidence indicates that glycaemic control should be prioritised for people with T2DM in the era of COVID-19 and practical advice on the use of T2DM medications during periods of acute illness remains important, particularly for healthcare professionals working in primary care who face multiple competing priorities. This article provides the latest update from the Improving Diabetes Steering Committee, including perspectives on the value of SGLT2is as cost-effective therapies within the T2DM treatment paradigm, with particular focus on the latest published evidence relating to the prevention or slowing of cardiorenal complications. The implications for ongoing and future approaches to diabetes care are considered in the light of the continuing coronavirus pandemic, and relevant aspects of international treatment guidelines are highlighted with practical advice on the appropriate use of SGLT2is in commonly occurring T2DM clinical scenarios. The 'SGLT2i Prescribing Tool for T2DM Management', previously published by the Steering Committee, has been updated to reflect the latest evidence and is provided in the Supplementary Materials to help support clinicians delivering T2DM care.
Some personal views with regard to the functions of statistics
Creators: name: De Cristofaro, R.
Publisher: name: Dep. of Statistical Sciences "Paolo Fortunati", Università di Bologna
Year: 2013

description: Descriptive, inductive and decision theory approaches to statistics are discussed in this paper. According to the author, the contrast between descriptive and inductive statistics is artificial since any description of the reality constitutes in fact an induction. In the words of Boldrini (1942) "every statistic, even one that seems documentary, has an investigative preoccupation and therefore, above all, an hypothesis". However, the author is doubtful also about inductive statistics conceived as a methodology of knowledge. Concerning the philosophy or pragmatism, it is worth while noticing that the interpretation due to Smith (1984) does not fit for any pragmatist in general and even less for its founders. In the last part of the paper, the functions of statistics are once more discussed from a neo-rationalistic viewpoint and a distinction between the process of analysis bringing forth to discovery and the operative process of decision is posed. The same application of probability in statistics is contested. Indeed, probability is an analytic tool we may use to explore hypotheses. Therefore, it cannot be reserved only for inference or decision, as we may see at present time in the text-books.
description: Statistica; Vol 47, No 4 (1987)
Some notes on a history of teaching statistics in Italy
Creators: name: Ottaviani, M. G.
Publisher: name: Dep. of Statistical Sciences "Paolo Fortunati", Università di Bologna
Year: 2013

description: The history of Statistics teaching in Italy can be more easily understood remembering that at the beginning of the 1800's as well as after the 1815 Congress of Vienna, Italy was divided into many States.
Therefore the teaching of Statistics developed in different ways in the Universities of the different States.
In the initial phase (1811-1859) the teaching of Statistics started in the Law Faculties of Naples, Pavia and Padua Universities reflecting the earlier experiences of France and Austria in this field. In the following period (1859-1875) however an unexpected phenomenon manifested itself. Statistics began to be taught together with Geography in the Faculties of Philosophy and Letters within the Kingdom of Sardinia. As the political unity of Italy was gradually realized by the Kingdom of Sardinia, it was the above university organization of Statistics that expanded into the new born Kingdom of Italy. Scientific debate and concern about the linkage of Statistics to Geography accompanied this expansion. These difficulties were overcome in 1875 when the teaching of "Statistics" became mandatory in all Faculties of Law in the Italian Kingdom. From 1875 until 1923 Statistics continued to consolidate its position in the Faculties of Law and in the Superior Schools of Commerce. However the subject was not received with favour by jurists who felt that Statistics was not part of their discipline. On the other hand as the study of Statistical Methods developed, Italian Statisticians became increasingly conscious of the necessity that Statistics be taught not only in the Law Faculties, but also in other faculties. Between 1923 and 1930 Statistics left the Faculties of Law for its own autonomy. In 1927 the Schools of Statistics were created in Rome and Padua, and in 1936 the Faculty of Statistical, Demographically and Actuarial Sciences was officially founded in Rome where the School of Statistics was consequently abolished. The school offered a Diploma in Statistics and in addition the Faculty offered a Degree in Statistical and Demographically Sciences and a Degree in Statistical and Actuarial Sciences.
Therefore the university teaching of Statistics in Italy, which at the begging of the 1800's originated and was inspired by the experience of other European countries with different political and cultural traditions, and which passed through many difficulties and provoked wide debate, was by the end of the 1930's organized in a way that has no parallel in other countries.
description: Statistica; Vol 47, No 4 (1987)
title: Greenhouse gas and volatile organic compound emissions of additive-treated whole-plant maize silage: part A—anaerobic fermentation period
Creators: name: Deeken, Hauke Ferdinand
name: Büscher, Wolfgang
name: Trimborn, Manfred
name: Schmithausen, Alexander J.
name: Weiß, Kirsten
name: Lipski, André
name: Maack, Gerd-Christian
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: Carbon dioxide
subject: Carbon footprint
subject: Corn silage
subject: Ethanol
subject: Ethyl acetate
subject: Lactic acid bacteria
subject: Methane
subject: Nitrous oxide
subject: Silage additives
subject: 540 Chemie und zugeordnete Wissenschaften

description: Background: Silage emits climate- and environment-relevant gases during fermentation and feed-out periods. This trial aimed to determine the unknown carbon dioxide (CO2), methane, nitrous oxide, ethanol, and ethyl acetate emissions of constant maize silage material over both periods. The results will be published in two consecutive articles (Part A: anaerobic fermentation period, Part B: aerobic storage period).Methods: The untreated control (CON) was compared with the chemical additive treatment (CHE; 0.5 g sodium benzoate and 0.3 g potassium sorbate per kg fresh matter) and the biological additive treatment (BIO; 108 colony-forming units (CFU) Lentilactobacillus buchneri and 107 CFU Lactiplantibacillus plantarum per kg fresh matter). Barrel silos (n = 4) were connected to gas bags to quantify gas formation during anaerobic fermentation (30 or 135 ensiling days). Glass jar silos (n = 12) were used for laboratory silage analysis.Results: CHE produced significantly (p < 0.05) less gas (6.7 ± 0.3 L per kg dry matter ensiled material (kgDM) until ensiling day 14.0 ± 0.0) and ethanol (8.6 ± 1.5 mg kgDM–1) than CON did (8.5 ± 0.2 L kgDM–1 until ensiling day 19.5 ± 6.4; 12.2 ± 1.5 (mg ethanol) kgDM–1). BIO indicates prolonged gas formation (9.1 ± 0.9 L kgDM–1 until ensiling day 61.3 ± 51.9; 12.0 ± 2.1 mg kgDM–1). CO2 is the main component of the gas formed. All treatments formed methane and nitrous oxide in small quantities. CON emitted significantly more CO2eq emissions than BIO and less than CHE (p < 0.05). Additives had no effect on ethyl acetate gas emissions. For BIO, ethanol concentrations in the material (rS = 0.609, p < 0.05) and gas quantities (rS = 0.691, p < 0.05) correlate with ethyl acetate gas quantities. All the treatments exhibited decreasing gas and CO2 quantities, and the dry matter mass increased between ensiling days 14 and 30 (− 0.810 ≤ rS ≤ 0.442; p < 0.05 to p = 0.20).Conclusion: Silage generates climate- and environmental-relevant gases during fermentation and silage additives affect this pattern. Gas formation exceeds the fixation potential, and the carbon footprint of silage fermentation is negative.Graphical Abstract
Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index.
Creators: name: Gurtan, Allan
name: Dominy, John
name: Khalid, Shareef
name: Vong, Linh
name: Caplan, Shari
name: Currie, Treeve
name: Richards, Sean
name: Lamarche, Lindsey
name: Denning, Daniel
name: Shpektor, Diana
name: Gurinovich, Anastasia
name: Rasheed, Asif
name: Hameed, Shahid
name: Saeed, Subhan
name: Saleem, Imran
name: Jalal, Anjum
name: Abbas, Shahid
name: Sultana, Raffat
name: Rasheed, Syed Zahed
name: Memon, Fazal-Ur-Rehman
name: Shah, Nabi
name: Ishaq, Mohammad
name: Khera, Amit V
name: Danesh, John
name: Frossard, Philippe
name: Saleheen, Danish
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: subject: Research Article
subject: Biology and life sciences
subject: Medicine and health sciences
subject: Engineering and technology
subject: FOS: Engineering and technology
subject: Research and analysis methods
subject: Physical sciences
subject: FOS: Physical sciences

description: Novel drug targets for sustained reduction in body mass index (BMI) are needed to curb the epidemic of obesity, which affects 650 million individuals worldwide and is a causal driver of cardiovascular and metabolic disease and mortality. Previous studies reported that the Arg95Ter nonsense variant of GPR151, an orphan G protein-coupled receptor, is associated with reduced BMI and reduced risk of Type 2 Diabetes (T2D). Here, we further investigate GPR151 with the Pakistan Genome Resource (PGR), which is one of the largest exome biobanks of human homozygous loss-of-function carriers (knockouts) in the world. Among PGR participants, we identify eleven GPR151 putative loss-of-function (plof) variants, three of which are present at homozygosity (Arg95Ter, Tyr99Ter, and Phe175LeufsTer7), with a cumulative allele frequency of 2.2%. We confirm these alleles in vitro as loss-of-function. We test if GPR151 plof is associated with BMI, T2D, or other metabolic traits and find that GPR151 deficiency in complete human knockouts is not associated with clinically significant differences in these traits. Relative to Gpr151+/+ mice, Gpr151-/- animals exhibit no difference in body weight on normal chow and higher body weight on a high-fat diet. Together, our findings indicate that GPR151 antagonism is not a compelling therapeutic approach to treatment of obesity.
Eustrophopsis ornatus
Creators: name: Johnston, M. Andrew
name: Warner, William B.
name: Pollock, Darren A.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Tetratomidae
Eustrophopsis
Eustrophopsis ornatus

description: Eustrophopsis ornatus (Van Dyke, 1928)
 Eustrophinus ornatus Van Dyke 1928: 251.
Literature Records: Cochise, Pima, Santa Cruz counties (Pollock 2012).
Specimens Examined: ASUHIC (Apache, Pima, Cochise counties).
Notes. We add Apache County to the county-level distribution given by Pollock (2012).
description: Published as part of Johnston, M. Andrew, Warner, William B. & Pollock, Darren A., 2024, New Records and a Checklist of Melandryidae and Tetratomidae Known from Arizona, USA (Coleoptera: Tenebrionoidea), pp. 53-60 in The Coleopterists Bulletin 78 (1) on page 57, DOI: 10.1649/0010-065X-78.1.53, http://zenodo.org/record/13243675
Nerolidol loaded beta cyclodextrin nanoparticles: a promising strategy for inducing apoptosis in breast cancer cells (MCF-7)
Creators: name: Venkatesan, Kamalesh Balakumar
name: Alamelu, Saravanan
name: Srinivasan, Manoj Kumar
name: Pachaiappan, Pugalendhi
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Biophysics
Biochemistry
Space Science
Medicine
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: This study investigates the synthesis, characterization and anticancer efficacy of nerolidol-loaded beta cyclodextrin polymeric nanoparticles (NER-βCD-NPs) against MCF-7 breast cancer cells. Nerolidol, a sesquiterpene with anti-inflammatory, antioxidant, antimicrobial and anticancer properties, faces challenges of poor solubility and bioavailability, limiting its therapeutic potential. Breast cancer, a leading cause of cancer-related deaths in women, necessitates alternative therapies with fewer side effects compared to conventional chemotherapy. NER-βCD-NPs were synthesized and characterized using UV–visible spectroscopy, fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), dynamic light scattering (DLS), zeta potential analysis and differential scanning calorimetry (DSC). Drug encapsulation efficiency and in vitro release were analyzed using HPLC, while molecular docking assessed NER-βCD interactions. Characterization confirmed successful nanoparticle synthesis. UV-visible spectra and FTIR indicated encapsulation-specific changes, SEM revealed surface morphology, and DLS, zeta potential and DSC analyses demonstrated increased size and stability. The encapsulation efficiency was 84.9%, with 86% NER release at pH 5.4 over 48 h. Docking studies supported strong binding between NER and βCD (binding energy: −3.55 kcal/mol). Cytotoxicity assays showed significant MCF-7 cell inhibition. Mechanistic studies revealed reactive oxygen species (ROS) generation, mitochondrial dysfunction, nuclear changes and cell cycle arrest in the G0–G1 phase. Molecular analysis demonstrated apoptosis through upregulation of Bax, Caspase 6, Caspase 9 and Cytochrome c, alongside Bcl-2 downregulation. These results highlight NER-βCD-NPs as a promising strategy for breast cancer therapy, offering targeted delivery and enhanced therapeutic efficacy while mitigating nerolidol limitations. Further studies are warranted to validate their potential in clinical applications.
Investigating cooperative behavior in the hub protein LC8 via molecular dynamics simulations
Creators: name: Santos, Shelby
name: Barbar, Elisar
name: Zuckerman, Daniel
Publisher: name: Oregon Health and Science University
Year: 2024
Subjects: Ebolavirus
Cooperative Behavior
Hemorrhagic Fever, Ebola
Molecular Dynamics Simulation
Peptides
Calorimetry
Thermodynamics
Signal Transduction
Apoptosis

description: LC8 is a key molecular hub protein involved in a wide array of cellular processes (e.g., apoptosis, viral interactions, signal transduction). LC8 interacts with over 100 binding partners, some of which are intrinsically disordered (ID) regions of proteins. LC8, functioning as a homodimer, utilizes a two-step binding process essential for the structural organization of its client peptides. Isothermal titration calorimetry experiments indicate significant cooperativity occurs in the two binding steps, but the structural basis of the behavior remains unknown because there is negligible conformational change in binding. Using 1µs all-atom molecular dynamics (MD) simulations, this work explores the atomistic mechanisms of LC8's cooperative behavior and its effects on local and global dynamics for multiple client peptides. The peptides in this study include segments of several proteins exhibiting diverse binding thermodynamics: BIM, Swallow, IC, nNOS, as well as Ebola virus, which are considered at both their experimental lengths and at a standard length to carefully examine effects due to sequence alone. This work aims to generate a structural understanding of LC8's cooperative mechanisms and introduces a site-specific 'cooperativity index' for quantifying these interactions, advancing our knowledge of protein dynamics and interactions at the molecular level.
Eustrophus tomentosus Say 1826
Creators: name: Johnston, M. Andrew
name: Warner, William B.
name: Pollock, Darren A.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Tetratomidae
Eustrophus
Eustrophus tomentosus

description: Eustrophus tomentosus Say, 1826
 Eustrophus tomentosus Say 1826: 239.
Literature Records: Coconino, Pima counties (Pollock 2012).
Specimens Examined: None beyond those cited above.
description: Published as part of Johnston, M. Andrew, Warner, William B. & Pollock, Darren A., 2024, New Records and a Checklist of Melandryidae and Tetratomidae Known from Arizona, USA (Coleoptera: Tenebrionoidea), pp. 53-60 in The Coleopterists Bulletin 78 (1) on page 57, DOI: 10.1649/0010-065X-78.1.53, http://zenodo.org/record/13243675
title: Initial labor market conditions and subsequent fertility behavior
Creators: name: Ramos, Vincent Jerald
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: Fertility
subject: Labor market entry
subject: Fixed-term employment
subject: Recession entry
subject: Optimal full matching
subject: 300 Sozialwissenschaften

description: The conditions upon which young adults enter the labor market have been demonstrated to affect various later-life employment and family formation outcomes. After the 2008–2009 Global Financial Crisis, a thick strand of the literature has shown that precarious initial employment leads to postponed childbearing and higher ultimate childlessness. However, it is not only individual conditions that matter. Broader macroeconomic conditions upon entry also matter. The “scarring” literature has illustrated the consequences of entering the labor market during a recession on later life outcomes. Speaking to both strands and using detailed employment and birth histories of labor market entrants in Germany, this paper examines the effects of initial conditions, operationalized using fixed-term employment and recession year entry, on subsequent fertility behavior. To partly address bias from endogenous selection into initial conditions, we employ a two-step estimation strategy combining a non-parametric optimal full matching step and a parametric event history modeling step using the matched data. Results suggest that entering the labor market with a fixed-term contract is persistently and negatively associated with first births up to a decade after entry, and this pattern is pronounced only among women, whereas entering during a recession has persistent negative associations only among men.
siRNA-guided dual-targeting nanocarrier for breast cancer treatment
Creators: name: Kilicay, Ebru
name: Sahin, Betul
name: Karahaliloglu, Zeynep
name: Celik, Ekin
name: Hazer, Baki
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: This study aimed to develop a thermoplastic polyurethane-oleic acid-based nanosystem (TPU-Ole NPs) incorporating siRNA and curcumin (CUR) to overcome multidrug resistance in breast cancer by silencing the c-myc gene. TPU-Ole and CUR-loaded NPs were prepared via solvent evaporation and coated with poly-L-lysine (PLL) for siRNA attachment. NPs were characterised by dynamic light scattering (DLS) for mean diameter, polydispersity index (PDI), and zeta potential (ZP). Encapsulation (EE) and loading efficiencies (LE) were measured by NanoDrop. Release (pH 5.0; 7.4) and storage stability (pH 7.4) were evaluated using the eppendorf method. siRNA binding was confirmed by agarose gel electrophoresis. Gene silencing and apoptosis were assessed by RT-PCR and flow cytometry. Mean diameter, PDI, and ZP of NPs were 170 ± 2 nm, 0.011 ± 0.080, and −27.5 ± 0.11 mV. EE and LE were 75 ± 0.12 and 14.2 ± 0.06%. Sustained release and good stability were observed. siRNA-CUR-NPs efficiently silenced c-myc and induced apoptosis in MCF-7 cells.
Hallomenus (Hallomenus) scapularis Melsheimer 1846
Creators: name: Johnston, M. Andrew
name: Warner, William B.
name: Pollock, Darren A.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Tetratomidae
Hallomenus
Hallomenus scapularis

description: Hallomenus (Hallomenus) scapularis Melsheimer, 1846
(Figs. 3A, B)
 Hallomenus scapularis Melsheimer 1846: 57.
Literature Records: None.
Digital Records: Two records from Pima and Yavapai counties (GBIF 2023).
 Specimens Examined: “ USA: AZ: Apache Co. // Baldy Trailhead on//Hwy. 273;33.9661, // -109. 502;viii.15.2019 // ex. Sparassis radicata || Collector // W.B. Warner ” (4 ASUHIC); “ USA:AZ: Apache Co. // near Glabedon camp- // ground;33.9279,-109 //.4869; Aug. 14, 2019 // ex. Sparassis radicata || Collector // W.B. Warner ” (4 ASUHIC); “ Arizona: Apache Co. // 15.5 miles W Eagar // 34.0662, ­109.5443 // June 24, 2022 On // fence Kyle E. Schnepp ” (1 FSCA); “ Arizona: Cochise Co. // Rustler Park 8400’ // 31.9029, -109.2774 // August 16, 2019 under // pine bark Kyle E. Schnepp ” (1 FSCA, elytra entirely testaceous, possibly slightly teneral); “ USA:AZ: Coconino Co. // FS300, 2.4 km NW jct. // with FS105; 34.3321 // -110.9633; vii.30- viii. // 17.2019; VFlight inter- // cept trap; WB Warner” (13 ASUHIC); “ USA: AZ: Cochise Co. // Huachuca Mts.; 0.8 rd. // mi. SW Reef; 31.4238 // ­110.2991; July 15­24 // 2018; VFlight intercept // trap; W.B. Warner ” (1 ASUHIC).
 Notes. New state record. This species is recognizable by its lighter-colored humeral spots. There is a moderate degree of color variation within the series examined where the base color can range from brown to piceous. The pronotum often has at least a distinct light median longitudinal stripe but it can also be nearly concolorous and the pronotum can be the same hue as the elytra or range from darker to lighter in color. The humeral spots vary slightly in size and contrast from the rest of the elytra. Coloration did not seem to covary with sex or any other obvious character. Five digitized records are only determined to genus (from Cochise and Pima counties and deposited in the Triplehorn Insect Collection at The Ohio State University) and could represent either this species or the following species.
description: Published as part of Johnston, M. Andrew, Warner, William B. & Pollock, Darren A., 2024, New Records and a Checklist of Melandryidae and Tetratomidae Known from Arizona, USA (Coleoptera: Tenebrionoidea), pp. 53-60 in The Coleopterists Bulletin 78 (1) on page 57, DOI: 10.1649/0010-065X-78.1.53, http://zenodo.org/record/13243675
Crashkurs Personalentwicklung
Creators: name: Heß, Michael
name: Grund, Sven
name: Weiss, Wolfgang
Publisher: name: Haufe Group
Year: 2020
Subjects: Fortbildung

description: - Personalentwicklung planen und umsetzen - Schritt-für-Schritt-Anleitungen und zahlreiche Praxisbeispiele - Mit vielen Arbeitshilfen online Gute Maßnahmen zur Personalentwicklung erweitern Wissen und Kompetenzen von Mitarbeitern und binden Leistungsträger langfristig an das Unternehmen. Doch was ist Personalentwicklung überhaupt und welche Rolle nimmt man als "PE-Vertreter" im eigenen Unternehmen ein? Dieser Crashkurs beschreibt Inhalte und Methoden, Herangehensweisen und Instrumente und beantwortet alle wesentlichen Fragen. Sie erhalten ein Prozessmodell, das praxisnah und Schritt für Schritt alle entsprechenden Maßnahmen unterstützt. Neu in der 2. Auflage: Neue, aktualisierte und weiterentwickelte Werkzeuge und Methoden, besonders im Bereich evidenzbasierte Personalentwicklung und Organisationsentwicklung Quelle: Verlagsinformation
Life after redundancy: what happens next for journalists when they leave newsrooms
Creators: name: Zion, Laurie
name: Dodd, Andrew
name: Ricketson, Matthew
name: Sherwood, Merryn
name: O'Donnell, Penny
name: Marjoribanks, Timothy
Publisher: name: Swinburne
Year: 2024

description: The planned 125 editorial job redundancies at Fairfax Media is a huge blow to those working within some of Australia’s most established newsrooms, to their readers, and to the capacity of established media to operate as a site of public engagement. The proposed cuts prompted a seven-day strike by staff at the Sydney Morning Herald, The Age, and the Australian Financial Review, which between them face a reduction of 25% of all editorial staff. The announcement of these redundancies is just the latest in a protracted series of job cuts in Australian newsrooms since 2012. But what comes next for those who will be leaving? Our New Beats research team has been following the experiences of 225 news workers whose positions were made redundant between 2012 and 2014 to see how their post-redundancy careers evolved. Findings from our annual surveys of this group point to some common concerns – including how redundancy affects health, income, and the gaining of new skills.
Sampling properties of Dagum model for income distribution
Creators: name: Latorre, G.
Publisher: name: Dep. of Statistical Sciences "Paolo Fortunati", Università di Bologna
Year: 2013

description: In this article we firstly investigate on the sampling properties of the model proposed by Dagum and successively we use those properties to find the asymptotic sampling distribution of two measures of inequality of income. More specifically, in the first part we indicate the system of equations which will provide the maximum likelihood estimates of the parameters of the model and find the Fisher's information matrix which can be used to make general inferences on the parameters of the model. In the second part, instead, by means of the functional relations linking the measures of inequality and the parameters of the Dagum model and by using the maximum likelihood invariance property we find the asymptotic sampling distributions of the measures of inequality.
description: Statistica; Vol 48, No 1/2 (1988)
Boostrapping, Jackknife and James-Stein estimators
Creators: name: Ardeni, P. G.
Publisher: name: Dep. of Statistical Sciences "Paolo Fortunati", Università di Bologna
Year: 2013

description: In this article, the most recent results in resampling methods in regression analysis are reviewed. Different classes of estimators are studied and compared the simple "jackknife" the weighted "jackknife" variance estimator for the case of heteroscedastic errors, the variable "jackknife", and the general "bootstrap" estimator. A brief description of Stein-rule estimators in the case of pre-testing estimation then follows. As an application, it is shown how to improve on pre-testing efficiency, following a Stein-rule estimator, by applying bootstrap methods to the estimated variances.
description: Statistica; Vol 48, No 1/2 (1988)
On the homogeneity measures
Creators: name: Gastaldi, T.
Publisher: name: Dep. of Statistical Sciences "Paolo Fortunati", Università di Bologna
Year: 2013

description: The usual homogeneity indices take their lowest value according to a minimum homogeneity state which is not always verificable in the examined statistical collective. The A. shows that the reference to a minimum homogeneity situation not actually achievable could lead to contradictions. To resolve these inconsistencies the A. suggests referring to the actual minimum homogeneity state. It is possible to find a homogeneity measure by a quantification of the diversity between the examined situation and the minimum actual state. This procedure elicits generalizations of the usual homogeneity indices.
A different way of finding homogeneity indices is based on an indirect comparison between distributions made by the appropriate quantities inferred from them. Using this procedure the A. also constructs a homogeneity curve and a homogeneity ratio that allows him to find a correlation between the homogeneity notion and the concentration notion.
description: Statistica; Vol 48, No 1/2 (1988)
A note on the identification and preliminary estimation of MA models
Creators: name: Corduas, M.
Publisher: name: Dep. of Statistical Sciences "Paolo Fortunati", Università di Bologna
Year: 2013

description: In this paper, we examine some problems that the sampling fluctuation of the estimated autocorrelation function causes in the identification and preliminary estimation of a first order Moving Average model.
We reconsider the idea that the identification criterion, based on the approximate confidence limits around the estimated autocorrelation function, could restrict the theoretical parametric space, where the process is defined. In particular, we evaluate approximately the probability that a MA process can be correctly identified by using that criterior. Furthermore, we consider the moment estimator of  q and ,with a similar approach, we compute the probability that this estimator provides estimates out of the invertibility  region. A simulation study which confirms the theoretical results concludes the paper.
description: Statistica; Vol 48, No 1/2 (1988)