cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplementary Information from How predation shapes the social interaction rules of shoaling fish
Creators: name: Herbert-Read, James E.
name: Rosén, Emil
name: Szorkovszky, Alex
name: Ioannou, Christos C.
name: Rogell, Björn
name: Perna, Andrea
name: Indar W. Ramnarine
name: Kotrschal, Alexander
name: Kolm, Niclas
name: Krause, Jens
name: Sumpter, David J. T.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: Predation is thought to shape the macroscopic properties of animal groups, making moving groups more cohesive and coordinated. Precisely, how predation has shaped individuals' fine-scale social interactions in natural populations, however, is unknown. Using high-resolution tracking data of shoaling fish (Poecilia reticulata) from populations differing in natural predation pressure, we show how predation adapts individuals' social interaction rules. Fish originating from high predation environments formed larger, more cohesive, but not more polarized groups than fish from low predation environments. Using a new approach to detect the discrete points in time when individuals decide to update their movements based on the available social cues, we determine how these collective properties emerge from individuals' microscopic social interactions. We first confirm predictions that predation shapes the attraction–repulsion dynamic of these fish, reducing the critical distance at which neighbours move apart, or come back together. While we find strong evidence that fish align with their near neighbours, we do not find that predation shapes the strength or likelihood of these alignment tendencies. We also find that predation sharpens individuals' acceleration and deceleration responses, implying key perceptual and energetic differences associated with how individuals move in different predation regimes. Our results reveal how predation can shape the social interactions of individuals in groups, ultimately driving differences in groups' collective behaviour.
Spindle dynamics and cell cycle regulation of dynein in the budding yeast, Saccharomyces cerevisiae
Creators: name: Skibbens, Robert V.
name: Yeh, Elaine
name: Cheng, Judy W.
name: Bloom, Kerry
name: Salmon, E.D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: We have used time-lapse digital- and video-enhanced differential interference contrast (DE-DIC, VE-DIC) microscopy to study the role of dynein in spindle and nuclear dynamics in the yeast Saccharomyces cerevisiae. The real-time analysis reveals six stages in the spindle cycle. Anaphase B onset appears marked by a rapid phase of spindle elongation, simultaneous with nuclear migration into the daughter cell. The onset and kinetics of rapid spindle elongation are identical in wild type and dynein mutants. In the absence of dynein the nucleus does not migrate as close to the neck as in wild-type cells and initial spindle elongation is confined primarily to the mother cell. Rapid oscillations of the elongating spindle between the mother and bud are observed in wild-type cells, followed by a slower growth phase until the spindle reaches its maximal length. This stage is protracted in the dynein mutants and devoid of oscillatory motion. Thus dynein is required for rapid penetration of the nucleus into the bud and anaphase B spindle dynamics. Genetic analysis reveals that in the absence of a functional central spindle (ndcl), dynein is essential for chromosome movement into the bud. Immunofluorescent localization of dynein-beta- galactosidase fusion proteins reveals that dynein is associated with spindle pole bodies and the cell cortex: with spindle pole body localization dependent on intact microtubules. A kinetic analysis of nuclear movement also revealed that cytokinesis is delayed until nuclear translocation is completed, indicative of a surveillance pathway monitoring nuclear transit into the bud.
Supplementary Tables of sequence data, meme analyses and RNA structures from Molecular trade-offs in RNA ligases affected the modular emergence of complex ribozymes at the origin of life.
Creators: name: Dhar, Nisha
name: Weinberg, Marc S.
name: Michod, Richard E.
name: Durand, Pierre M.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 20101 Astrobiology
subject: FOS: Physical sciences

description: The supplementary tables provide the raw data for oligonucleotides, sequence data, meme analyses and secondary structures of RNA molecules
Regression of Environmental Noise in LIGO Data
Creators: name: Tiwari, Vaibhav
name: Drago, Marco
name: Frolov, Valery
name: Klimenko, Sergey
name: Mitselmakher, Guenakh
name: Necula, Valentin
name: Prodi, Giovanni
name: Re, Virginia
name: Salemi, Francesco
name: Vedovato, Gabriele
name: Yakushin, Igor
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We address the problem of noise regression in the output of gravitational-wave (GW) interferometers, using data from the physical environmental monitors (PEM). The objective of the regression analysis is to predict environmental noise in the gravitational-wave channel from the PEM measurements. One of the most promising regression method is based on the construction of Wiener-Kolmogorov filters. Using this method, the seismic noise cancellation from the LIGO GW channel has already been performed. In the presented approach the Wiener-Kolmogorov method has been extended, incorporating banks of Wiener filters in the time-frequency domain, multi-channel analysis and regulation schemes, which greatly enhance the versatility of the regression analysis. Also we presents the first results on regression of the bi-coherent noise in the LIGO data.
The Prime Spectrum of Quantum $SL_3$ and the Poisson-prime Spectrum of its Semi-classical Limit
Creators: name: Fryer, Siân
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics

description: A bijection $ψ$ is defined between the prime spectrum of quantum $SL_3$ and the Poisson prime spectrum of $SL_3$, and we verify that $ψ$ and $ψ^{-1}$ both preserve inclusions of primes, i.e. that $ψ$ is in fact a homeomorphism between these two spaces. This is accomplished by developing a Poisson analogue of Brown and Goodearl's framework for describing the Zariski topology of spectra of quantum algebras, and then verifying directly that in the case of $SL_3$ these give rise to identical pictures on both the quantum and Poisson sides. As part of this analysis, we study the Poisson primitive spectrum of $\mathcal{O}(SL_3)$ and obtain explicit generating sets for all of the Poisson primitive ideals.
description: Minor updates, clarifications, etc throughout the text. To appear in Transactions of the London Mathematical Society
Supplementary Figures providing detailed experimental protocols and methodologies from Molecular trade-offs in RNA ligases affected the modular emergence of complex ribozymes at the origin of life.
Creators: name: Dhar, Nisha
name: Weinberg, Marc S.
name: Michod, Richard E.
name: Durand, Pierre M.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 20101 Astrobiology
subject: FOS: Physical sciences

description: The supplementary figures provide details of the experimental protocols and methodologies as well as the raw data for ligation reactions
(103809) Sandra Treharne Watson
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
¿Frases coloquiales o discriminación inconsciente?
Creators: name: Suing, Abel
Publisher: name: Zenodo
Year: 2020
Subjects: COVID-19
discriminación
derechos
identidad
Ecuador
Universidad
CES
regulación
cholo

description: Participación en espacio de opinión de http://antena7.ec/, que se emite desde la ciudad de Loja en Ecuador.
Factorisation of X^n-alpha over finite fields
Creators: name: Soranzo, Gabriel
Publisher: name: Zenodo
Year: 2022
Subjects: factorisation
finite field
cyclotomic polynomial

description: We are studying the order of the irreducible factors of polynomials X^n-a over finite fields Fp. The note only use basic concepts of finite fields theory. All follows from the fact that X^n-a divides X^(nl)-1 if a is a l-root of unity and from the other fact, proved below (and consequence of the cyclicity of the subset of invertible elements in finite field), that all the polynomials X^n-a with a a primitive l-root have irreducible factors with the same ditribution of orders.
Supplementary Tables of sequence data, meme analyses and RNA structures from Molecular trade-offs in RNA ligases affected the modular emergence of complex ribozymes at the origin of life
Creators: name: Dhar, Nisha
name: Weinberg, Marc S.
name: Michod, Richard E.
name: Durand, Pierre M.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 20101 Astrobiology
subject: FOS: Physical sciences

description: The supplementary tables provide the raw data for oligonucleotides, sequence data, meme analyses and secondary structures of RNA molecules
A Metastable Intermediate State of Microtubule Dynamic Instability That Differs Significantly between Plus and Minus Ends
Creators: name: Tran, P.T.
name: Salmon, E.D.
name: Walker, R.A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1997

description: The current two-state GTP cap model of microtubule dynamic instability proposes that a terminal crown of GTP-tubulin stabilizes the microtubule lattice and promotes elongation while loss of this GTP-tubulin cap converts the microtubule end to shortening. However, when this model was directly tested by using a UV microbeam to sever axoneme-nucleated microtubules and thereby remove the microtubule's GTP cap, severed plus ends rapidly shortened, but severed minus ends immediately resumed elongation (Walker, R.A., S. Inoué, and E.D. Salmon. 1989. J. Cell Biol. 108: 931–937).To determine if these previous results were dependent on the use of axonemes as seeds or were due to UV damage, or if they instead indicate an intermediate state in cap dynamics, we performed UV cutting of self-assembled microtubules and mechanical cutting of axoneme-nucleated microtubules. These independent methods yielded results consistent with the original work: a significant percentage of severed minus ends are stable after cutting. In additional experiments, we found that the stability of both severed plus and minus ends could be increased by increasing the free tubulin concentration, the solution GTP concentration, or by assembling microtubules with guanylyl-(α,β)-methylene-diphosphonate (GMPCPP).Our results show that stability of severed ends, particularly minus ends, is not an artifact, but instead reveals the existence of a metastable kinetic intermediate state between the elongation and shortening states of dynamic instability. The kinetic properties of this intermediate state differ between plus and minus ends. We propose a three-state conformational cap model of dynamic instability, which has three structural states and four transition rate constants, and which uses the asymmetry of the tubulin heterodimer to explain many of the differences in dynamic instability at plus and minus ends.
(103811) Christopher Lewis
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Layered Adaptive Importance Sampling
Creators: name: Martino, L.
name: Elvira, V.
name: Luengo, D.
name: Corander, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computation (stat.CO)
subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Monte Carlo methods represent the "de facto" standard for approximating complicated integrals involving multidimensional target distributions. In order to generate random realizations from the target distribution, Monte Carlo techniques use simpler proposal probability densities to draw candidate samples. The performance of any such method is strictly related to the specification of the proposal distribution, such that unfortunate choices easily wreak havoc on the resulting estimators. In this work, we introduce a layered (i.e., hierarchical) procedure to generate samples employed within a Monte Carlo scheme. This approach ensures that an appropriate equivalent proposal density is always obtained automatically (thus eliminating the risk of a catastrophic performance), although at the expense of a moderate increase in the complexity. Furthermore, we provide a general unified importance sampling (IS) framework, where multiple proposal densities are employed and several IS schemes are introduced by applying the so-called deterministic mixture approach. Finally, given these schemes, we also propose a novel class of adaptive importance samplers using a population of proposals, where the adaptation is driven by independent parallel or interacting Markov Chain Monte Carlo (MCMC) chains. The resulting algorithms efficiently combine the benefits of both IS and MCMC methods.
description: Related Matlab codes: an iterative version at http://www.lucamartino.altervista.org/CODE_LAIS_v03.zip and a non-iterative version at http://www.lucamartino.altervista.org/LAIS_non_iterative_code.zip, Statistics and Computing, 2016
Supplementary Figures providing detailed experimental protocols and methodologies from Molecular trade-offs in RNA ligases affected the modular emergence of complex ribozymes at the origin of life
Creators: name: Dhar, Nisha
name: Weinberg, Marc S.
name: Michod, Richard E.
name: Durand, Pierre M.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 20101 Astrobiology
subject: FOS: Physical sciences

description: The supplementary figures provide details of the experimental protocols and methodologies as well as the raw data for ligation reactions
(103938) Trevor Edward Lewis
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Development and Spread of High-Yielding Varieties of Wheat and Rice in the Less Developed Nations (Sixth Edition)
Creators: name: Dalrymple, Dana G.
name: Dalrymple, Dana G.
Publisher: name: Unknown
Year: 1978
Subjects: subject: Crop Production/Industries
subject: International Development
subject: Research and Development/Tech Change/Emerging Technologies
subject: wheat
subject: rice
subject: green revolution
subject: high-yielding varieties
subject: seed
subject: agricultural research
subject: agricultural development
subject: developing countries

description: The use of high-yielding varieties (HYV’s) of wheat and rice has expanded sharply in the less developed countries (LDC’s) in recent years. This report reviews the development of these varieties and statistically documents their yearly spread. Major emphasis is placed on semi-dwarf varieties (1) developed at the International Maize and Wheat Improvement Center (CIMMYT) in Mexico and the International Rice Research Institute (IRRI) in the Philippines, and/or (2) offspring of these or similar varieties developed in national breeding programs. Data cover the 12-year period from the 1965/66 crop year, when these varieties first came into use, through 1976/77. They are subject to a number of qualifications. As of 1976/77, the total HYV wheat and rice area in the non-Communist LDC’s totaled about 54.7 million hectares (135.1 million acres). Of this, about 29.4 million ha. (72.6 million acres) were wheat and 25.3 million ha. (62.5 million acres) were rice. HYV’s represented about 34.5 percent of the total wheat and rice area; HYV wheat accounted for 44.3 percent of total wheat area and HYV rice accounted for 27.5 percent of total rice area. Additional areas of HYV’s were planted in Israel, South Africa, and Taiwan, and in the Communist nations. The largest proportion of the non-Communist LDC HYV wheat and rice area in 1976/77 was located in Asia, which represented 80 percent of the total. Asia was followed by Latin America with 11 percent, the Near East with 8 percent, and Africa with less than 1 percent. India had by far the largest HYV area, representing about 52 percent of the total. Over the 12-year period from 1965/66 to 1976/77, the HYV wheat and rice area in Asia rose steadily. The rate of increase is expected to slow in the future because of both supply and demand factors.
description: This is the sixth edition of this report. Previous editions were issued by the Economic Research Service (now a part of the Economics, Statistics, and Cooperative Service), U.S. Department of Agriculture, under the same title and FAER number in August 1976 and July 1974. Earlier editions, with a slightly different title and publication number (or no number), were issued in February 1972, January 1971, and November 1969. All are supplanted by this edition. Funding for this project was, as in the past, provided through the Office of Agriculture, Development Support Bureau, AID.
title: Επίδραση των συνθηκών κατεργασίας στις αναπτυσσόμενες δυνάμεις κοπής στο φραιζάρισμα με βαρελοειδή κοπτικά εργαλεία
Creators: name: Θεοδωροπουλου Αθανασια
Publisher: name: Technical University of Crete
Year: 2023

description: Στην παρούσα διπλωματική εργασία θα διεξαχθεί μια σειρά πειραμάτων, σκοπός των οποίων είναι ο προσδιορισμός των αναπτυσσόμενων δυνάμεων κοπής κατά το φραιζάρισμα σε συγκεκριμένες συνθήκες κοπής. Τα εργαλεία που θα χρησιμοποιηθούν θα είναι κονδυλοφόρα βαρελοειδούς απόληξης και το υλικό στο οποίο θα γίνει η κατεργασία θα είναι τεμάχιο αλουμινίου. Σε κάθε πειραματική διάταξη θα εναλλάσσονται οι συνθήκες κοπής. Συγκεκριμένα οι συνθήκες που θα διαφοροποιούνται θα είναι: η ταχύτητα κοπής, ταχύτητα πρόωσης ,το ακτινικό βάθος κοπής καθώς και η κλίση της τραπέζης στην οποία στηρίζεται η πλάκα.
Precision reconstruction of the dark matter-neutrino relative velocity from N-body simulations
Creators: name: Inman, Derek
name: Emberson, J. D.
name: Pen, Ue-Li
name: Farchi, Alban
name: Yu, Hao-Ran
name: Harnois-Deraps, Joachim
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Discovering the mass of neutrinos is a principle goal in high energy physics and cosmology. In addition to cosmological measurements based on two-point statistics, the neutrino mass can also be estimated by observations of neutrino wakes resulting from the relative motion between dark matter and neutrinos. Such a detection relies on an accurate reconstruction of the dark matter-neutrino relative velocity which is affected by non-linear structure growth and galaxy bias. We investigate our ability to reconstruct this relative velocity using large N-body simulations where we evolve neutrinos as distinct particles alongside the dark matter. We find that the dark matter velocity power spectrum is overpredicted by linear theory whereas the neutrino velocity power spectrum is underpredicted. The magnitude of the relative velocity observed in the simulations is found to be lower than what is predicted in linear theory. Since neither the dark matter nor the neutrino velocity fields are directly observable from galaxy or 21 cm surveys, we test the accuracy of a reconstruction algorithm based on halo density fields and linear theory. Assuming prior knowledge of the halo bias, we find that the reconstructed relative velocities are highly correlated with the simulated ones with correlation coefficients of 0.94, 0.93, 0.91 and 0.88 for neutrinos of mass 0.05, 0.1, 0.2 and 0.4 eV. We confirm that the relative velocity field reconstructed from large scale structure observations such as galaxy or 21 cm surveys can be accurate in direction and, with appropriate scaling, magnitude.
description: 10 pages, 11 figures
Differential Association of Syntrophin Pairs with the Dystrophin Complex
Creators: name: Froehner, Stanley
name: Adams, Marvin
name: Peters, Matthew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1997

description: The syntrophins are a multigene family of intracellular dystrophin-associated proteins comprising three isoforms, α1, β1, and β2. Based on their domain organization and association with neuronal nitric oxide synthase, syntrophins are thought to function as modular adapters that recruit signaling proteins to the membrane via association with the dystrophin complex. Using sequences derived from a new mouse β1-syntrophin cDNA, and previously isolated cDNAs for α1- and β2-syntrophins, we prepared isoform-specific antibodies to study the expression, skeletal muscle localization, and dystrophin family association of all three syntrophins. Most tissues express multiple syntrophin isoforms. In mouse gastrocnemius skeletal muscle, α1- and β1-syntrophin are concentrated at the neuromuscular junction but are also present on the extrasynaptic sarcolemma. β1-syntrophin is restricted to fast-twitch muscle fibers, the first fibers to degenerate in Duchenne muscular dystrophy. β2-syntrophin is largely restricted to the neuromuscular junction.The sarcolemmal distribution of α1- and β1-syntrophins suggests association with dystrophin and dystrobrevin, whereas all three syntrophins could potentially associate with utrophin at the neuromuscular junction. Utrophin complexes immunoisolated from skeletal muscle are highly enriched in β1- and β2-syntrophins, while dystrophin complexes contain mostly α1- and β1-syntrophins. Dystrobrevin complexes contain dystrophin and α1- and β1-syntrophins. From these results, we propose a model in which a dystrophin–dystrobrevin complex is associated with two syntrophins. Since individual syntrophins do not have intrinsic binding specificity for dystrophin, dystrobrevin, or utrophin, the observed preferential pairing of syntrophins must depend on extrinsic regulatory mechanisms.
Integrin-mediated Activation of MAP Kinase Is Independent of FAK: Evidence for Dual Integrin Signaling Pathways in Fibroblasts
Creators: name: Juliano, R.L.
name: Chen, Qiming
name: Schaller, Michael
name: Aukhil, Ikramuddin
name: Shen, Yu
name: Lin, Tsung
name: Romer, Lewis
name: Aplin, Andrew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1997

description: Integrin-mediated cell adhesion causes activation of MAP kinases and increased tyrosine phosphorylation of focal adhesion kinase (FAK). Autophosphorylation of FAK leads to the binding of SH2-domain proteins including Src-family kinases and the Grb2–Sos complex. Since Grb2–Sos is a key regulator of the Ras signal transduction pathway, one plausible hypothesis has been that integrin-mediated tyrosine phosphorylation of FAK leads to activation of the Ras cascade and ultimately to mitogen activated protein (MAP) kinase activation. Thus, in this scenario FAK would serve as an upstream regulator of MAP kinase activity. However, in this report we present several lines of evidence showing that integrin-mediated MAP kinase activity in fibroblasts is independent of FAK. First, a β1 integrin subunit deletion mutant affecting the putative FAK binding site supports activation of MAP kinase in adhering fibroblasts but not tyrosine phosphorylation of FAK. Second, fibroblast adhesion to bacterially expressed fragments of fibronectin demonstrates that robust activation of MAP kinase can precede tyrosine phosphorylation of FAK. Finally, we have used FRNK, the noncatalytic COOH-terminal domain of FAK, as a dominant negative inhibitor of FAK autophosphorylation and of tyrosine phosphorylation of focal contacts. Using retroviral infection, we demonstrate that levels of FRNK expression sufficient to completely block FAK tyrosine phosphorylation were without effect on integrin-mediated activation of MAP kinase. These results strongly suggest that integrin-mediated activation of MAP kinase is independent of FAK and indicate the probable existence of at least two distinct integrin signaling pathways in fibroblasts.
A comparative study on two different expressions of Bulk viscosity in the PNJL model
Creators: name: Saha, Kinkar
name: Upadhaya, Sudipa
name: Ghosh, Sabyasachi
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We have gone through a comparative study on two different kind of bulk viscosity expressions by using a common dynamical model. The Polyakov-Nambu-Jona-Lasinio (PNJL) model in the realm of mean-field approximation, including up to eight quark interactions for 2+1 flavor quark matter, is treated for this common dynamics. We have probed the numerical equivalence as well as discrepancy of two different expressions for bulk viscosity at vanishing quark chemical potential. Our estimation of bulk viscosity to entropy density ratio follows a decreasing trend with temperature, which is observed in most of the earlier investigations. We have also extended our estimation for finite values of quark chemical potential.
description: 13 pages, 4 figures
Role of Polo Kinase and Mid1p in Determining the Site of Cell Division in Fission Yeast
Creators: name: Steever, Alexander
name: Pringle, John
name: Bähler, Jürg
name: Wang, Yu-li
name: Gould, Kathleen
name: McCollum, Dannel
name: Wheatley, Sally
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1998

description: The fission yeast Schizosaccharomyces pombe divides symmetrically using a medial F-actin– based contractile ring to produce equal-sized daughter cells. Mutants defective in two previously described genes, mid1 and pom1, frequently divide asymmetrically. Here we present the identification of three new temperature-sensitive mutants defective in localization of the division plane. All three mutants have mutations in the polo kinase gene, plo1, and show defects very similar to those of mid1 mutants in both the placement and organization of the medial ring. In both cases, ring formation is frequently initiated near the cell poles, indicating that Mid1p and Plo1p function in recruiting medial ring components to the cell center. It has been reported previously that during mitosis Mid1p becomes hyperphosphorylated and relocates from the nucleus to a medial ring. Here we show that Mid1p first forms a diffuse cortical band during spindle formation and then coalesces into a ring before anaphase. Plo1p is required for Mid1p to exit the nucleus and form a ring, and Pom1p is required for proper placement of the Mid1p ring. Upon overexpression of Plo1p, Mid1p exits the nucleus prematurely and displays a reduced mobility on gels similar to that of the hyperphosphorylated form observed previously in mitotic cells. Genetic and two-hybrid analyses suggest that Plo1p and Mid1p act in a common pathway distinct from that involving Pom1p. Plo1p localizes to the spindle pole bodies and spindles of mitotic cells and also to the medial ring at the time of its formation. Taken together, the data indicate that Plo1p plays a role in the positioning of division sites by regulating Mid1p. Given its previously known functions in mitosis and the timing of cytokinesis, Plo1p is thus implicated as a key molecule in the spatial and temporal coordination of cytokinesis with mitosis.
MAKTABGACHA TA'LIM TASHKILOTI TARBIYACHI ROLLI POZISTIYALARNING AHAMIYATI
Creators: name: Rustamova, Surayo
Publisher: name: Zenodo
Year: 2024

description: Ushbu ilmiy maqolada maktabgacha ta’lim tashkiloti tarbiyachilarning rolli pozisiyalari o‘rganilgan. Tarbiyachilarning rolli pozisiyalari kasbiy faoliyatiga ta’siri masalalari dolzarbligi ko’rsatilib o’tilgan. Bolalar bilan bo‘ladigan munosabatlarda rolli pozitsiyaning ahamiyati haqida ilmiy fikrlar berilgan.
Adiabatic Elimination of Gaussian Subsystems from Quantum Dynamics under Continuous Measurement
Creators: name: Černotík, Ondřej
name: Vasilyev, Denis V.
name: Hammerer, Klemens
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: An ever broader range of physical platforms provides the possibility to study and engineer quantum dynamics under continuous measurements. In many experimental arrangements the system of interest is monitored by means of an ancillary device, whose sole purpose is to transduce the signal from the system to the measurement apparatus. Here, we present a method of adiabatic elimination when the transducer consists of an arbitrary number of bosonic modes with Gaussian dynamics while the measured object can be any quantum system. Crucially, our approach can cope with the highly relevant case of finite temperature of the transducer, which is not easily achieved with other methods. We show that this approach provides a significant improvement in the readout of superconducting qubits in circuit QED already for a few thermal excitations, and admits to adiabatically eliminate optomechanical transducers.
description: 13 pages + Appendix, 8 figures
(103949) Mary James
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Chemical sequencing of sequence-defined polymers by controlled degradation : studies and applications
Creators: name: Dahlhauser, Samuel Davis
name: 0000-0002-4034-5172
Publisher: name: The University of Texas at Austin
Year: 2021
Subjects: Sequence-defined polymers
Depolymerization
Digital polymers
Information storage
Intramolecular cyclization
Urethane
Carbamate
Sequencing
Abiotic polymer
Self-sequencing

description: Sequence-defined polymers are a promising platform of discovery for the fields of biomimetics, self-assembly, catalysis, and information storage. The power of these polymers lies in their primary structure, which can beget complex chemical processes. Here we report the solution-phase and the high-yielding solid-phase syntheses of discrete oligourethanes and methods for their chain-end depolymerization for sequencing, resulting in rapid and robust characterization of this class of oligomers and polymers, without the use of MS/MS. Crucial to the sequencing is the inherent reactivity of the terminal alcohol to “unzip” the oligomers, in a controlled and iterative fashion, releasing each monomer as a 2-oxazolidinone. The process utilizes the effective molarity of the terminal alcohol, as well as the steric compression of the sidechain methylenes to control the rate of cyclization. It was observed that these macromolecules do not auto-depolymerize at room temperature or in the absence of base, and are generally stable to hydrolysis. The mechanism of depolymerization was confirmed as a 5-exo-trig intramolecular cyclization, and is capable of tolerating a wide diversity of sidechain functionalities as well as crude or complex sample mixtures. This robust immolative self-sequencing paradigm was utilized in the development of a complete workflow for the encoding and decoding of digital information within the macromolecular sequence-defined urethanes. Within the encoding and decoding schema, a highly configurable software was developed that is capable taking any information and converting it to the preferred positional numeral system (such as hexadecimal), which can then be synthesized into the urethanes, and ultimately sequenced back to decode the molecular information. A parallel synthesis methodology was developed for the simultaneous synthesis of numerous sequence-defined urethanes, and utilized to synthesize 18 unique 10-mer oligourethanes that encoded a passage from Jane Austen’s Mansfield Park. A parallel sequencing methodology was developed to simultaneously sequence all 18 oligomers, where the data were fed into our decoding software and the information transformed back to its original state. Currently, we are working to advance the sequencing methodology to allow multiple urethanes to be stored and sequenced within the same solution, utilizing isotopic labelling as unique mass tags for their discreet characterization. Ultimately, we plan to use this technology for cryptography and steganography, wherein we imbed and store a 256-bit molecular cipher key. Only upon extraction, sequencing, and decoding can the encrypted information be accessed.
title: Философ права Аркадий Николаевич Фатеев в Праге: до, во время и после Второй мировой войны
Creators: name: Абашник, В. А.
Publisher: name: Реноме
Year: 2022

description: В статье представлены основные этапы жизненного и творческого пути философа права Аркадия Фатеева. Сначала указаны главные черты его преподавательской и публикационной деятельности в Харьковском университете до 1920 г. Далее рассмотрены ключевые аспекты его «пражского периода», или «чехословацкого периода», после 1922 г., в том числе его преподавание на Русском юридическом факультете, а также в Русском народном (свободном) университете. В приложении впервые представлены три письма Аркадия Фатеева к Валентину Булгакову, который являлся последним секретарем писателя Льва Толстого.
title: Anthropologie de la lose ou la lose de l'anthropologue. Réflexions sur le déclin d'un gang
title: A lost ethnography. Reflections on the decline of a gang
Creators: name: Lamotte, Martin
Publisher: name: ethnographiques.org
Year: 2020
Subjects: subject: déclin
subject: gang
subject: secret
subject: perte
subject: loser
subject: transformation
subject: revisite
subject: decline
subject: gang
subject: secret
subject: lost
subject: looser
subject: transformation
subject: revisit

description: Lors d'une revisite annuelle d'un terrain commencé il y a sept années, l'anthropologue se trouve face au déclin du gang Los Ñetas sur lequel il a travaillé. Ce retour sur le terrain et la disparition, relative, des Ñetas permettent d'aborder une série de réflexions sur la nature du déclin et la façon de le percevoir en anthropologie. Comment décrire le déclin d'un groupe ? Comment les acteurs sociaux vivent-ils, supportent-ils, voire affrontent-ils, le délitement de leur propre groupe ? Afin d'approcher ces questions, cet article traite de l'enquête elle-même comme un terrain d'investigation et se centre sur la relation entre l'anthropologue et l'un des acteurs importants du gang, son chef Mikey. À travers la description de trois situations de terrain, je reviendrai sur cette relation avec Mikey et la façon dont elle se construit dans un contexte de déclin du gang. Ces trois situations disent quelque chose de ce moment liminal dans lequel les Ñetas sont engagés. Moment crépusculaire peut-être, qui, comme je le montrerai en conclusion, est épistémologiquement inaugural (Adell L'Homme, 218 (2), p. 67-83.">2016). mots-clefs : déclin, gang, secret, perte, loser, transformation, revisite.
description: A lost ethnography. Reflections on the decline of a gang During an annual revisit to a fieldsite studied for the last seven years, the anthropologist was faced with the decline of the gang Los Ñetas on which he had worked. This return and the relative disappearance of the Ñetas allow him to propose a series of reflections on the nature of decline and the ways of perceiving it in anthropology. How can one describe the decline of a group ? How do social actors experience, tolerate or face up to the disintegration of their own group ? In order to approach these questions, this article starts with the research itself as a field of investigation and focuses on the relationship between the anthropologist and one of the important actors in the gang, its leader Mikey. Through the description of three field situations, he revisits this relationship with Mikey and the way it is (re)constructed in light of this decline. These three situations say something about the liminal moment in which the Ñetas are engaged. A twilight moment perhaps which, as he shows in his conclusion, is epistemologically inaugural (Adell L'Homme, 218 (2), p. 67-83.">2016). keywords : decline, gang, secret, lost, looser, transformation, revisit.
R-Ras Signals through Specific Integrin α Cytoplasmic Domains to Promote Migration and Invasion of Breast Epithelial Cells
Creators: name: Parise, Leslie
name: Keely, Patricia
name: Cox, Adrienne
name: Rusyn, Elena
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: Specificity and modulation of integrin function have important consequences for cellular responses to the extracellular matrix, including differentiation and transformation. The Ras-related GTPase, R-Ras, modulates integrin affinity, but little is known of the signaling pathways and biological functions downstream of R-Ras. Here we show that stable expression of activated R-Ras or the closely related TC21 (R-Ras 2) induced integrin-mediated migration and invasion of breast epithelial cells through collagen and disrupted differentiation into tubule structures, whereas dominant negative R-Ras had opposite effects. These results imply novel roles for R-Ras and TC21 in promoting a transformed phenotype and in the basal migration and polarization of these cells. Importantly, R-Ras induced an increase in cellular adhesion and migration on collagen but not fibronectin, suggesting that R-Ras signals to specific integrins. This was further supported by experiments in which R-Ras enhanced the migration of cells expressing integrin chimeras containing the α2, but not the α5, cytoplasmic domain. In addition, a transdominant inhibition previously noted only between integrin β cytoplasmic domains was observed for the α2 cytoplasmic domain; α2β1-mediated migration was inhibited by the expression of excess α2 but not α5 cytoplasmic domain-containing chimeras, suggesting the existence of limiting factors that bind the integrin α subunit. Using pharmacological inhibitors, we found that R-Ras induced migration on collagen through a combination of phosphatidylinositol 3-kinase and protein kinase C, but not MAPK, which is distinct from the other Ras family members, Rac, Cdc42, and N- and K-Ras. Thus, R-Ras communicates with specific integrin α cytoplasmic domains through a unique combination of signaling pathways to promote cell migration and invasion.
Figure S1. Heatmap of normalised human gene expression showing gene names from Novel and divergent genes in the evolution of placental mammals.
Creators: name: Dunwell, Thomas L.
name: Paps, Jordi
name: Holland, Peter W. H.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60408 Genomics

description: Same data and analysis as Figure 6 but showing gene names.
(103810) Philippa Lewis
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A Systematic Study of Chloride Ion Solvation in Water using van der Waals Inclusive Hybrid Density Functional Theory
Creators: name: Bankura, Arindam
name: Santra, Biswajit
name: DiStasio, Robert A.
name: Swartz, Charles W.
name: Klein, Michael L.
name: Wu, Xifan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: In this work, the solvation and electronic structure of the aqueous chloride ion solution was investigated using Density Functional Theory (DFT) based \textit{ab initio} molecular dynamics (AIMD). From an analysis of radial distribution functions, coordination numbers, and solvation structures, we found that exact exchange ($E_{\rm xx}$) and non-local van der Waals (vdW) interactions effectively \textit{weaken} the interactions between the Cl$^-$ ion and the first solvation shell. With a Cl-O coordination number in excellent agreement with experiment, we found that most configurations generated with vdW-inclusive hybrid DFT exhibit 6-fold coordinated distorted trigonal prism structures, which is indicative of a significantly disordered first solvation shell. By performing a series of band structure calculations on configurations generated from AIMD simulations with varying DFT potentials, we found that the solvated ion orbital energy levels (unlike the band structure of liquid water) strongly depend on the underlying molecular structures. In addition, these orbital energy levels were also significantly affected by the DFT functional employed for the electronic structure; as the fraction of $E_{\rm xx}$ was increased, the gap between the highest occupied molecular orbital of Cl$^-$ and the valence band maximum of liquid water steadily increased towards the experimental value.
description: 13 pages, 8 figures
Nonlinear time-series analysis revisited
Creators: name: Bradley, Elizabeth
name: Kantz, Holger
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: In 1980 and 1981, two pioneering papers laid the foundation for what became known as nonlinear time-series analysis: the analysis of observed data---typically univariate---via dynamical systems theory. Based on the concept of state-space reconstruction, this set of methods allows us to compute characteristic quantities such as Lyapunov exponents and fractal dimensions, to predict the future course of the time series, and even to reconstruct the equations of motion in some cases. In practice, however, there are a number of issues that restrict the power of this approach: whether the signal accurately and thoroughly samples the dynamics, for instance, and whether it contains noise. Moreover, the numerical algorithms that we use to instantiate these ideas are not perfect; they involve approximations, scale parameters, and finite-precision arithmetic, among other things. Even so, nonlinear time-series analysis has been used to great advantage on thousands of real and synthetic data sets from a wide variety of systems ranging from roulette wheels to lasers to the human heart. Even in cases where the data do not meet the mathematical or algorithmic requirements to assure full topological conjugacy, the results of nonlinear time-series analysis can be helpful in understanding, characterizing, and predicting dynamical systems.
δ-catenin, an Adhesive Junction–associated Protein Which Promotes Cell Scattering
Creators: name: Kosik, Kenneth
name: Cavallo, Robert
name: Orecchio, Lisa
name: Zhou, Jianhua
name: Peifer, Mark
name: Paredes, Mercedes
name: Lu, Qun
name: Medina, Miguel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: The classical adherens junction that holds epithelial cells together consists of a protein complex in which members of the cadherin family linked to various catenins are the principal components. δ-catenin is a mammalian brain protein in the Armadillo repeat superfamily with sequence similarity to the adherens junction protein p120ctn. We found that δ-catenin can be immunoprecipitated as a complex with other components of the adherens junction, including cadherin and β-catenin, from transfected cells and brain. The interaction with cadherin involves direct contact within the highly conserved juxtamembrane region of the COOH terminus, where p120ctn also binds. In developing mouse brain, staining with δ-catenin antibodies is prominent towards the apical boundary of the neuroepithelial cells in the ventricular zone. When transfected into Madin-Darby canine kidney (MDCK) epithelial cells δ-catenin colocalized with cadherin, p120ctn, and β-catenin. The Arm domain alone was sufficient for achieving localization and coimmunoprecipitation with cadherin. The ectopic expression of δ-catenin in MDCK cells altered their morphology, induced the elaboration of lamellipodia, interfered with monolayer formation, and increased scattering in response to hepatocyte growth factor treatment. We propose that δ-catenin can regulate adhesion molecules to implement the organization of large cellular arrays necessary for tissue morphogenesis.