cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The influence of the effective number of active and sterile neutrinos on the determination of the values of cosmological parameters
Creators: name: Chernikov, P. A.
name: Ivanchik, A. V.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the presented work we consider the influence of a hypothetical sterile neutrino (with eV-scale mass) on the determination of cosmological parameters. If it is detected, it will be necessary to include it into the $Λ\rm CDM$ model with the fixed values of its mass $m_{\rm s}$ and mixing angle $θ_{s}$, which is the main method used through this paper. Apart from that, the seesaw mechanism requires there to be at least two sterile states, one of them being much heavier than the active ones. The heavier sterile state ($m_{s}\sim1$ keV) would decay and increase the effective number of active neutrinos. Therefore, the influence of a change in the effective number of relativistic neutrino species $N_{\rm eff}$ was studied as well, which could be caused by, for example, the decay processes of the above-mentioned sterile neutrinos, as well as processes leading to an increase in the temperature of relic neutrinos $T_{\rm CνB}$. The effects studied in this work lead to a significant change in the estimates of the cosmological parameters, including the value of $H_{0}$. It has been discovered that the accounting of the sterile neutrino with masses $m=1$ and $2.7$ eV leads to a decrease in the estimate of the current Hubble parameter value $H_{0}$ and, therefore, exacerbates the ``$H_{0}$-tension'' problem. An increase in the value of the effective number of relativistic neutrino species leads, on the contrary, to an increase in the $H_{0}$ estimate, resolving the above-mentioned problem at $N_{\rm eff}=3.0+0.9$, which is equivalent to an increase of the neutrino temperature up to $T ^{\,0}_{\rm CνB}=1.95+0.14\,\rm K$. At the same time, the rest of the cosmological parameters do not change significantly, leaving us within the framework of the standard $Λ\rm CDM$ model.
description: 19 pages, 6 figures
title: Forming a musical language: Compositional research on notions of structure and material and on associations between music, poetry and film
Creators: name: Ghikas, Panos
Publisher: name: Goldsmiths, University of London
Year: 2004

description: The objective in this compositional research has been to arrive at a state in which a compositional language is, to some extent, formed through a process of challenging personal perceptions and investigating the application of extra­-musical art forms. An initial concern with structure led to a study of the use of duality and the notion of indeterminacy. Subsequently, a partially self-referential system for deriving musical material was developed, in which the elements of pitch and rhythm are directly related through particular ratios. The apparent associations between poetry and music and a personal interest in Surrealism as a movement, led the course of research to a detailed exploration of Greek poet A. Embiricos' prose poem Many Times in The Night (1980). The poem's structural matrix was applied upon independently derived musical material and, through a series of analogies, a complex matrix for a time structure was established. A turn towards free improvisation and an interest in film language introduced new ideas on the temporal and sequential manipulation of structure and perception. The film-editing process as a sequence of events in time, and the layering of visual and temporal activity as a technique of creating an evolving density of sensory events provided the basis for expanding the compositional concern with duality and indeterminacy. The research process, as a mutable investigation of possible associations between music, poetry and film, appears to be itself an inevitably inconclusive form of compositional language, defined by the ideas of Surrealism, Serialism, indeterminacy, chance and improvisation.
PACNav: A collective navigation approach for UAV swarms deprived of communication and external localization
Creators: name: Ahmad, Afzal
name: Licea, Daniel Bonilla
name: Silano, Giuseppe
name: Baca, Tomas
name: Saska, Martin
Publisher: name: arXiv
Year: 2023
Subjects: subject: Robotics (cs.RO)
subject: Multiagent Systems (cs.MA)
subject: FOS: Computer and information sciences

description: This article proposes Persistence Administered Collective Navigation (PACNav) as an approach for achieving decentralized collective navigation of Unmanned Aerial Vehicle (UAV) swarms. The technique is based on the flocking and collective navigation behavior observed in natural swarms, such as cattle herds, bird flocks, and even large groups of humans. As global and concurrent information of all swarm members is not available in natural swarms, these systems use local observations to achieve the desired behavior. Similarly, PACNav relies only on local observations of relative positions of UAVs, making it suitable for large swarms deprived of communication capabilities and external localization systems. We introduce the novel concepts of path persistence and path similarity that allow each swarm member to analyze the motion of other members in order to determine its own future motion. PACNav is based on two main principles: (1) UAVs with little variation in motion direction have high path persistence, and are considered by other UAVs to be reliable leaders; (2) groups of UAVs that move in a similar direction have high path similarity, and such groups are assumed to contain a reliable leader. The proposed approach also embeds a reactive collision avoidance mechanism to avoid collisions with swarm members and environmental obstacles. This collision avoidance ensures safety while reducing deviations from the assigned path. Along with several simulated experiments, we present a real-world experiment in a natural forest, showcasing the validity and effectiveness of the proposed collective navigation approach in challenging environments. The source code is released as open-source, making it possible to replicate the obtained results and facilitate the continuation of research by the community.
description: 17 pages, 16 figures, journal paper
Probe Higgs boson pair production via the $3 \ell 2 j$ + missing $E_T$ mode
Creators: name: Li, Qiang
name: Li, Zhao
name: Yan, Qi-Shu
name: Zhao, Xiaoran
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We perform a detailed hadron-level study on the sensitivity of Higgs boson pair production via the $WW^{*}WW^{*}$ channel with the final state $3 \ell 2 j$ + missing $E_T$ at the LHC with the collision energy $\sqrt{S} = 14$ TeV and a future 100 TeV collider. To avoid the huge background from $pp \to Z W + \textrm{jets}$ processes, we confine to consider the four lepton patterns: $e^\pm e^\pm μ^\mp $ and $μ^\pm μ^\pm e^\mp$. We propose a partial reconstruction method to determine the most reliable combination. After that, we examine a few crucial observables which can discriminate efficiently signal and background events, especially we notice that the observable $m_{\rm T2}$ is very efficient. For the LHC 14 TeV collisions, with an accumulated 3000 fb$^{-1}$ dataset, we find that the sensitivity of this mode can reach up to 1.5 $σ$ for the Standard Model and the triple coupling of Higgs boson $λ_3$ in the simplest effective theory can be constrained into the range [-1, 8] at $95\%$ confidence level; at a 100 TeV collider with the integrated luminosity 3000 fb$^{-1}$, the sensitivity can reach up to 13 $σ$ for the Standard Model and we find that all values of $λ_3$ in the effective theory can be covered up to 3$σ$ even without optimising signals. To precisely measure the triple coupling of Higgs boson $λ_3=1$ of the Standard Model at a 100 TeV collider, by using the invariant mass of three leptons which is robust to against the contamination of underlying events and pileup effects and by performing a $χ^2$ analysis, we find that it can be determined into a range [0.8, 1.5] at $95\%$ confidence level.
description: Added references
RanBP1, a velocardiofacial/DiGeorge syndrome candidate gene, is expressed at sites of mesenchymal/epithelial induction
Creators: name: LaMantia, Anthony-Samuel
name: Lee, James
name: Gassman, Andrew
name: Maynard, Thomas
name: Lieberman, Jeffrey
name: Bhasin, Naina
name: Haskell, Gloria
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: RanBP1, a velocardiofacial syndrome/DiGeorge syndrome candidate gene, is expressed in the frontonasal processes, branchial arches, aortic arches, and limb buds. At these sites, RanBP1 apparently coincides with neural crest-derived mesenchymal cells. In addition, RanBP1 is expressed in the forebrain as well as in hindbrain regions previously associated with crest-derived mesenchymal cells.
The lateral somitic frontier: dorso-ventral aspects of anterio-posterior regionalization in avian embryos
Creators: name: Nowicki, Julie
name: Takimoto, Ryoko
name: Burke, Ann Campbell
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: Patterning events along the anterior-posterior (AP) axis of vertebrate embryos result in the distribution of muscle and bone forming a highly effective functional system. A key aspect of regionalized AP patterning results from variation in the migratory pattern of somite cells along the dorsal-ventral (DV) axis of the body. This occurs as somite cell populations expand around the axis or migrate away from the dorsal midline and cross into the lateral plate. The fate of somitic cells has been intensely studied and many details have been reported about inductive signaling from other tissues that influence somite cell fate and behavior. We are interested in understanding the specific differences between somites in particular AP regions and how these differences contribute to the global pattern of the organism. Using orthotopic transplants of segmental plate between quail and chick embryos, we have mapped the interface of the somitic and lateral plate mesoderm during the formation of the body wall in cervical and thoracic regions. This interface does not change dramatically in the mid-cervical region, but undergoes extensive changes in the thoracic region. Based on this regional mapping and consistent with the extensive literature, we suggest a revised method of classifying regions of the body wall that relies on embryonic cell lineages rather than adult functional criteria.
(100297) Elizabeth Mary Parry Jones
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Safety and Immune Responses Following Anti-PD-1 Monoclonal Antibody Infusions in Healthy Persons With Human Immunodeficiency Virus on Antiretroviral Therapy
Creators: name: Cha, Raymond
name: Paccaly, Anne
name: Overton, Edgar T
name: Benson, Constance A
name: Eron, Joseph J
name: Moseley, Kendall F
name: Miller, Elizabeth
name: Campbell, Danielle M
name: McKhann, Ashley
name: Bosch, Ronald J
name: Hendrickx, Steven
name: Kuritzkes, Daniel R
name: Messer, Michael
name: Li, Jonathan Z
name: Tressler, Randall
name: Wimbish, Chanelle L
name: Morse, Gene D
name: Jankovic, Vladimir
name: Macatangay, Bernard J C
name: Hardy, W David
name: Gay, Cynthia L
name: A5370 Team
Publisher: name: Oxford University Press (OUP)
Year: 2024

description:
Background: T cells in people with human immunodeficiency virus (HIV) demonstrate an exhausted phenotype, and HIV-specific CD4+ T cells expressing programmed cell death 1 (PD-1) are enriched for latent HIV, making antibody to PD-1 a potential strategy to target the latent reservoir. Methods: This was a phase 1/2, randomized (4:1), double-blind, placebo-controlled study in adults with suppressed HIV on antiretroviral therapy with CD4+ counts ≥350 cells/μL who received 2 infusions of cemiplimab versus placebo. The primary outcome was safety, defined as any grade 3 or higher adverse event (AE) or any immune-related AE (irAE). Changes in HIV-1-specific polyfunctional CD4+ and CD8+ T-cell responses were evaluated. Results: Five men were enrolled (median CD4+ count, 911 cells/μL; median age, 51 years); 2 received 1 dose of cemiplimab, 2 received 2 doses, and 1 received placebo. One participant had a probable irAE (thyroiditis, grade 2); another had a possible irAE (hepatitis, grade 3), both after a single low-dose (0.3 mg/kg) infusion. The Safety Monitoring Committee recommended no further enrollment or infusions. All 4 cemiplimab recipients were followed for 48 weeks. No other cemiplimab-related serious AEs, irAEs, or grade 3 or higher AEs occurred. One 2-dose recipient of cemiplimab had a 6.2-fold increase in polyfunctional, Gag-specific CD8+ T-cell frequency with supportive increases in plasma HIV RNA and decreases in total HIV DNA. Conclusions: One of 4 participants exhibited increased HIV-1-specific T-cell responses and transiently increased HIV-1 expression following 2 cemiplimab infusions. The occurrence of irAEs after a single, low dose may limit translating the promising therapeutic results of cemiplimab for cancer to immunotherapeutic and latency reversal strategies for HIV. Clinical Trials Registration. NCT03787095.
Isoform-Specific Regulation of the Actin-Organizing Protein Palladin during TGF-β1-Induced Myofibroblast Differentiation
Creators: name: Leivonen, Suvi-Katri
name: Carpén, Olli
name: Rachlin, Andrew
name: Kähäri, Veli-Matti
name: Otey, Carol
name: Hinz, Boris
name: Rönty, Mikko
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Contractile myofibroblasts are responsible for remodeling of extracellular matrix during wound healing; however, their continued activity results in various fibrocontractive diseases. Conversion of fibroblasts into myofibroblasts is induced by transforming growth factor-beta1 (TGF-beta1) and is hallmarked by the neo-expression of alpha-smooth muscle actin (alpha-SMA), a commonly used myofibroblast marker. Moreover, myofibroblast differentiation and acquisition of the contractile phenotype involves functionally important alterations in the expression of actin-organizing proteins. We investigated whether myofibroblast differentiation is accompanied by changes in the expression of palladin, a cytoskeletal protein that controls stress fiber integrity. Palladin is expressed as several isoforms, including major 3Ig (90 kDa) and 4Ig (140 kDa) forms that differ in their N-terminal sequence. Expression of the 4Ig isoform is strongly induced in fibroblast stress fibers upon TGF-beta1 treatment preceding alpha-SMA upregulation. TGF-beta1 induced upregulation of palladin is mediated both by Smad and mitogen-activated protein kinase pathways. Furthermore, palladin 4Ig-isoform is co-expressed with alpha-SMA in vivo in experimental rat wounds and in human myofibroblast-containing lesions. Taken together these results identify palladin 4Ig as a novel marker of myofibroblast conversion in vitro and in vivo. They also provide for the first time information about the signaling cascades involved in the regulation of palladin expression.
Numerical study on ESR by making use of Wiener-Khinchin relation in time domain
Creators: name: Ikeuchi, Hiroki
name: Bertaina, Sylvain
name: Miyashita, Seiji
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: To evaluate ESR spectrum at finite temperatures for specified spatial configurations of spins is very important issue to study quantum spin systems. Although a direct numerical estimation of the Kubo formula provides exact data, the application is limited to small size of the system because of the restriction of the computer capacity. The method of the Fourier transform of the autocorrelation function improved the restriction. As an extension of the method, we propose a new method for numerical calculation of the ESR spectrum from the time evolution of the magnetization by making use of the Wiener-Khinchin theorem.
description: 12 pages, 6 figures; added section 3D
Rumor Classification through a Multimodal Fusion Framework and Ensemble Learning
Creators: name: Azri, Abderrazek
name: Favre, Cécile
name: Harbi, Nouria
name: Darmont, Jérôme
name: Noûs, Camille
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Artificial Intelligence (cs.AI)
subject: Computation and Language (cs.CL)
subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: The proliferation of rumors on social media has become a major concern due to its ability to create a devastating impact. Manually assessing the veracity of social media messages is a very time-consuming task that can be much helped by machine learning. Most message veracity verification methods only exploit textual contents and metadata. Very few take both textual and visual contents, and more particularly images, into account. Moreover, prior works have used many classical machine learning models to detect rumors. However, although recent studies have proven the effectiveness of ensemble machine learning approaches, such models have seldom been applied. Thus, in this paper, we propose a set of advanced image features that are inspired from the field of image quality assessment, and introduce the Multimodal fusiON framework to assess message veracIty in social neTwORks (MONITOR), which exploits all message features by exploring various machine learning models. Moreover, we demonstrate the effectiveness of ensemble learning algorithms for rumor detection by using five metalearning models. Eventually, we conduct extensive experiments on two real-world datasets. Results show that MONITOR outperforms state-of-the-art machine learning baselines and that ensemble models significantly increase MONITOR's performance.
description: Information Systems Frontiers, 2022
Coordinated Leading and Lagging Strand DNA Synthesis on a Minicircular Template
Creators: name: Kusakabe, Takahiro
name: Chastain, Paul
name: Lee, Joonsoo
name: Griffith, Jack
name: Richardson, Charles
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1998

description: The coordinated synthesis of both leading and lagging DNA strands is thought to involve a dimeric DNA polymerase and a looping of the lagging strand so that both strands can be synthesized in the same direction. We have constructed a minicircle with a replication fork that permits an assessment of the stoichiometry of the proteins and a measurement of the synthesis of each strand. The replisome consisting of bacteriophage T7 DNA polymerase, helicase, primase, and single-stranded DNA-binding protein mediates coordinated replication. The criteria for coordination are fulfilled: (1) a replication loop is formed, (2) leading and lagging strand synthesis are coupled, (3) the lagging strand polymerase recycles from one Okazaki fragment to another, and (4) the length of Okazaki fragments is regulated. T7 single-stranded DNA-binding protein is essential for coordination.
ВЛИЯНИЕ РИЗОСФЕРЫ ПОЧВЫ НА ЕЕ МИКРОБИОЛОГИЧЕСКУЮ АКТИВНОСТЬ
Creators: name: Дубинина Марина Николаевна
name: Лыхман Владимир Анатольевич
Publisher: name: Эпоха науки
Year: 2020
Subjects: ризосфера
микробная биомасса
ферментативная активность
биологический цикл элемента
азотфиксация

description: Область вокруг корневой массы растения является сферой максимальной концентрации микроорганизмов, а зона диаметром от нескольких микрометров до 2 мм непосредственно вблизи корня, обозначаемая термином «ризосфера», является отправной точкой исследования всех метаболических процессов в почве. Эти процессы катализируются продуцентами микроорганизмов – ферментами, количество и соотношение которых является свидетельством активности почвенной биоты. Динамические изменения состава и свойств почв непосредственно связаны с деятельностью микроорганизмов, эти же механизмы регулируют формирование корневой системы и развитие растений. В свою очередь, видовой состав прикорневых микроорганизмов зависит от вида растений. Почвенные микроорганизмы могут быть сгруппированы по различным признакам, как-то отношение к кислороду, углекислому газу; включение минеральных элементов в биологические циклы; минерализация органического вещества и т.п. Сами растения также могут быть сгруппированы по характерным особенностям ризосферы. При формировании севооборотов в агротехнологии наиболее распространена группировка сельскохозяйственных культур по отношению их к азотобактеру, так как фиксация атмосферного азота является одним из факторов минерального питания растений.
(100298) Henry Parry Jones
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Mutations in Human ARF Exon 2 Disrupt Its Nucleolar Localization and Impair Its Ability to Block Nuclear Export of MDM2 and p53
Creators: name: Zhang, Yanping
name: Xiong, Yue
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: The mammalian ARF-INK4a locus uniquely encodes two cell cycle inhibitors by using separate promoters and alternative reading frames. p16 INK4a maintains the retinoblastoma protein in its growth suppressive state while ARF stabilizes p53. We report that human ARF protein predominantly localizes to the nucleolus via a sequence within the exon 2–encoded C-terminal domain and is induced to leave the nucleolus by MDM2. ARF forms nuclear bodies with MDM2 and p53 and blocks p53 and MDM2 nuclear export. Tumor-associated mutations in ARF exon 2 disrupt ARF's nucleolus localization and reduce ARF's ability to block p53 nuclear export and to stabilize p53. Our results suggest an ARF-regulated MDM2-dependent p53 stabilization and link the human tumor-associated mutations in ARF with a functional alteration.
Analysis of the Okazaki Fragment Distributions along Single Long DNAs Replicated by the Bacteriophage T4 Proteins
Creators: name: Griffith, Jack
name: Chastain, Paul
name: Makhov, Alexander
name: Nossal, Nancy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: Rolling circle replication from M13 DNA circles was previously reconstituted in vitro using purified factors encoded by bacteriophage T4. The products are duplex circles with linear tails >100 kb. When T4 DNA polymerase deficient in 3' to 5' exonuclease activity was employed, electron microscopy revealed short single-stranded DNA "flaps" along the replicated tails. This marked the beginning of each Okazaki fragment, allowing an analysis of the lengths of sequential Okazaki fragments on individual replicating molecules. DNAs containing runs of Okazaki fragments of similar length were found, but most showed large length variations over runs of six or more fragments reflecting the broad population distribution.
(100295) George Thomas Evans
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
СНИЖЕНИЕ ТОКСИЧЕСКОГО СТРЕССА ЧЕРНОЗЕМА НА ПРИМЕРЕ ДИНАМИКИ СТРУКТУРНО-АГРЕГАТНОГО СОСТОЯНИЯ
Creators: name: Лыхман Владимир Анатольевич
name: Дубинина Марина Николаевна
Publisher: name: Эпоха науки
Year: 2020
Subjects: гуминовый препарат
гербицид
агрономически ценный агрегат
водопрочность
структурность.

description: Статья посвящена изучению влияния гуминового препарата в сочетании с различными дозами гербицидов на динамику структурно-агрегатного состояния чернозема обыкновенного карбонатного. Средства защиты растений действуют угнетающе как на патогенную почвенную микрофлору, так и на ризосферные микробиологические сообщества в целом. Подобный эффект может негативным образом сказаться на почвенной структуре. Внесение гуминовых препаратов призвано снизить токсическое действие гербицидов и оказать стимулирующее действие на структуроформирующие свойства микрофлоры.
Multi-armed Bandit Learning for TDMA Transmission Slot Scheduling and Defragmentation for Improved Bandwidth Usage
Creators: name: Dutta, Hrishikesh
name: Bhuyan, Amit Kumar
name: Biswas, Subir
Publisher: name: arXiv
Year: 2023
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: This paper proposes a Time Division Multiple Access (TDMA) MAC slot allocation protocol with efficient bandwidth usage in wireless sensor networks and Internet of Things (IoTs). The developed protocol has two primary components: a Multi-Armed Bandits (MAB)-based slot allocation mechanism for collision free transmission, and a Decentralized Defragmented Slot Backshift (DDSB) operation for improving bandwidth usage efficiency. The proposed framework is decentralized in that each node finds its transmission schedule independently without the control of any centralized arbitrator. The developed mechanism is suitable for networks with or without time synchronization, thus, making it suitable for low-complexity wireless transceivers for wireless sensor and IoT nodes. This framework is able to manage the trade-off between learning convergence time and bandwidth. In addition, it allows the nodes to adapt to topological changes while maintaining efficient bandwidth usage. The developed logic is tested for both fully-connected and arbitrary mesh networks with extensive simulation experiments. It is shown how the nodes can learn to select collision-free transmission slots using MAB. Moreover, the nodes learn to self-adjust their transmission schedules using a novel DDSB framework in order to reduce bandwidth usage.
(100296) Martha Jones
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
MA'LUMOTLARGA ASOSLANGAN BAHOLASH YONDASHUVLARINI IJTIMOIY MEDIA TARMOG'IDAN FOYDALANISH METODIKASI
Creators: name: Pazilova, Dilnoza
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqolada oliy ta’lim muassasalarida ijtimoiy media tarmoqlari yordamida talabalarning axborot kompetentligini rivojlantirish metodikasi ko’rib chiqiladi. Maqolada kasbiy-pedagogik vazifalar uchun nostandart yechimlar topish, tahliliy ko’nikmalarni rivojlantirish va talabalar o’rtasida innovatsion yondashuvlarni qo’llash orqali ularning kasbiy tayyorgarligini mustahkamlash usullari o’rganiladi. Tadqiqotda  neyron tarmoqlarga asoslangan vositalarning ahamiyati, Telegram botlari va boshqa ijtimoiy media platformalarining talabalarning mustaqil fikrlash qobiliyatlarini oshirish, ijodiy yondashuvlarini rivojlantirishga ta’siri muhokama qilinadi.
(100299) Judith Alice Jones
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Artificial Human Phantoms: Human proxy in testing microwave apparatus that have electromagnetic interaction with the human body
Creators: name: Mobashsher, A. T.
name: Abbosh, A. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Medical Physics (physics.med-ph)
subject: FOS: Physical sciences

description: In this manuscript, an effort is made in this review to address different state-of-the-art artificial tissue emulating (ATE) materials and phantom types for various operating frequencies, and fabrication procedures in order to have a better understanding of the pros and cons of various ATE phantoms which leads us to develop superior version of artificial human body substitute for various applications.
description: Accepted for publication in IEEE Microwave Magazine
Language Testing Course- Instructor: Dr. Elmira Esmaeelpour- Academic Year: 2024-2025
Creators: name: Esmaeelpour, Elmira
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 470401
subject: Applied linguistics and educational linguistics
classificationCode: 520405
subject: Psycholinguistics (incl. speech production and comprehension)

description: The "Language Testing Course" is structured into four main sections:Introduction and Fundamentals of Test Design: This section covers the basic concepts of language testing, including the definition and types of tests, and the objectives of test design. It delves into the characteristics of effective tests, focusing on validity, reliability, and practicality, and explores methods for evaluating these qualities.Test Design and Analysis: Students learn about different types of questions (e.g., multiple-choice, essay, task-based), their design, scoring principles, and question analysis. This section also includes a midterm exam to assess students' understanding.Performance Evaluation and Test Development: This section introduces the use of statistical analysis software such as R and SPSS for test design and analysis. It covers methods for evaluating learner performance and designing specific types of tests, including listening and speaking tests.International Tests and Test Ethics: The course concludes with an examination of standardized international tests like IELTS, TOEFL, and PTE, and emphasizes ethical principles in test design and administration.
Centrifuge model preparation methodology to simulate a layered gentle slope in soft clay
Creators: name: Soriano, Cristian
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 400502
subject: Civil geotechnical engineering

description: A dynamic centrifuge test was conducted at the Schofield Centre, University of Cambridge, UK to develop a model preparation methodology to simulate a gentle slope in soft clay, with a strength representative of Brazilian marine subsoils. Speswhite kaolin was utilized for the model preparation as it has comparative datasets with research projects involving physical models. Two types of containers were employed for model preparation. A strongbox for consolidation of the clay and a laminar container to simulate an infinite slope condition. The model was subjected to a series of earthquakes of varying amplitude and frequency content and the response was monitored utilizing accelerometers and displacement transducers. A particle image velocimetry (PIV) setup was proposed to obtain displacements and accelerations from the laminae of the container. This (PIV) method allowed us to obtain additional data that was in good agreement with the measurements from accelerometers and the displacement transducers. The centrifuge test presented in this paper was the first experience in preparing models in clay employing the laminar box at the Schofield Centre. The outcomes of the experiment provide a valuable reference for the preparation of models in soft clay employing a laminar container, and data sets for numerical simulations.
Published In
10th International Conference on Physical Modelling in Geotechnics 2022 (ICPMG2022)
Transcriptional Coactivator, CIITA, Is an Acetyltransferase that Bypasses a Promoter Requirement for TAFII250
Creators: name: Weissman, Jocelyn
name: Ting, Jenny
name: Howcroft, T.Kevin
name: Singer, Dinah
name: Yokoyama, Kazunari
name: Raval, Aparna
name: Kirshner, Susan
name: Zhu, Xin-Sheng
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: The CIITA coactivator is essential for transcriptional activation of MHC class II genes and mediates enhanced MHC class I transcription. We now report that CIITA contains an intrinsic acetyltransferase (AT) activity that maps to a region within the N-terminal segment of CIITA, between amino acids 94 and 132. The AT activity is regulated by the C-terminal GTP-binding domain and is stimulated by GTP. CIITA-mediated transactivation depends on the AT activity. Further, we report that, although constitutive MHC class I transcription depends on TAF(II)250, CIITA activates the promoter in the absence of functional TAF(II)250.
Les développements logiciels du LIGM référencés sur le serveur PLUME (2008-2013)
Creators: name: Gomez-Diaz, Teresa
Publisher: name: Zenodo
Year: 2013
Subjects: research software

description: The software produced in the Laboratoire d'informatique Gaspard-Monge was listed in the PLUME project platform between 2008 and 2013.
АДАПТИВНЫЙ ПРОГНОЗ КАЧЕСТВА ЗЕРНА ЯРОВОЙ ПШЕНИЦЫ В ЛЕСОСТЕПНОЙ ЗОНЕ ПРИ ДИФФЕРЕНЦИАЦИИ ПО РЕЖИМАМ ТЕМПЕРАТУРЫ И ОСАДКОВ
Creators: name: Сибирина Татьяна Фёдоровна
name: Мельникова Екатерина Валерьевна
name: Мордвинова Надежда Михайловна
name: Полубояринов Николай Александрович
name: Беляков Алексей Андреевич
Publisher: name: Эпоха науки
Year: 2020
Subjects: Адаптивный прогноз
адаптивный алгоритм
качество зерна яровой пшеницы
количество клейковины
индекс деформации клейковины
число падения α-амилазы зерна
натура зерна
научная гипотеза подобия
модель прогнозирования
вычислительный эксперимент
особые точки процесса

description: В комплексной агроэкологической оценке продуктивности яровой пшеницы, возделываемой в агробиогеоценозах лесостепной зоны, важное место отводится показателям качества получаемого зерна: количество клейковины зерна, индекс деформации клейковины зерна, число падения α-амилазы зерна, натура зерна. Предложенный авторами теоретический подход по адаптивному интервальному анализу и прогнозированию агроэкологических объектов, получил дальнейшее развитие в сформулированной научной гипотезе подобия урожайности и показателей качества яровой пшеницы, отнесённых к общему объекту — продукционному процессу яровой пшеницы, лимитируемому режимами температуры и осадков в данной среде агробиогеоценоза. Получение прогнозных оценок урожайности и показателей качества основывается на измерениях, расчётах и предвидении случайностей природы в полевых опытах. Разработанный математический аппарат гипотезы и выявленные на его основе закономерности позволили объяснить возможные вариации количества клейковины, числа падения α-амилазы зерна, и других показателей качества яровой пшеницы действующими, в данной среде агробиогеоценоза и в данном интервале периода вегетации, режимами температуры и осадков. На примере сорта Новосибирская 31 обоснована состоятельность адаптивного прогноза группы показателей качества зерна яровой пшеницы, как группы подобных показателей, формируемых под влиянием режимов температуры, осадков и других факторов лесостепной зоны Красноярского края. Вычислительный эксперимент по имитации показателей качества, выполненный в рамках гипотезы и с учётом вероятностных свойств лимитирующих факторов температуры и осадков, обнаружил особые точки этих показателей, характерных для лесостепной зоны Красноярского края.
Generic probabilistic inversion technique for geotechnical and transportation engineering applications
Creators: name: Hadidi, Rambod
Publisher: name: No Publisher Supplied
Year: 2007

description: A wide range of important problems in civil engineering can be classified as inverse problems. In such problems, the observational data related to the performance of a system is known, and the characteristics of the system or the input are sought. There are two general approaches to the solution of inverse problems: deterministic and probabilistic. Traditionally, inverse problems in civil engineering have been solved using a deterministic approach. In this approach, the objective is to find a model of the system that its theoretical response best fits the observed data. In deterministic approach to the solution of inverse problems, it is implicitly assumed that the uncertainties in data and theoretical models are negligible. However, this assumption is not valid in many applications, and therefore, effects of data and modeling uncertainties on the obtained solution should be evaluated. In this dissertation, a general probabilistic approach to the solution of the inverse problems is introduced, which offers the framework required to obtain uncertainty measures for the solution. Techniques for direct analytical evaluation and numerical approximation of the probabilistic solution using Monte Carlo Markov Chains (MCMC), with and without Neighborhood Algorithm (NA) approximation, are introduced and explained. The application of the presented concepts and techniques are then illustrated for three important classes of inverse problems in geotechnical and transportation engineering as application examples. These applications are: Falling Weight Deflectometer (FWD) backcalculation, model calibration based on geotechnical instrument measurements, and seismic waveform inversion for shallow subsurface characterization. For each application, the probabilistic formulation is presented; the solution is obtained; and the advantages of the probabilistic approach are illustrated and discussed.
Trauma-Informed Social Media: Towards Solutions for Reducing and Healing Online Harm
Creators: name: Scott, Carol F.
name: Marcu, Gabriela
name: Anderson, Riana Elyse
name: Newman, Mark W.
name: Schoenebeck, Sarita
Publisher: name: arXiv
Year: 2023
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Social media platforms exacerbate trauma, and many users experience various forms of trauma unique to them (e.g., doxxing and swatting). Trauma is the psychological and physical response to experiencing a deeply disturbing event. Platforms' failures to address trauma threaten users' well-being globally, especially amongst minoritized groups. Platform policies also expose moderators and designers to trauma through content they must engage with as part of their jobs (e.g., child sexual abuse). We consider how a trauma-informed approach might help address or decrease the likelihood of (re)experiencing trauma online. A trauma-informed approach to social media recognizes that everyone likely has a trauma history and that trauma is experienced at the individual, secondary, collective, and cultural levels. This paper proceeds by detailing trauma and its impacts. We then describe how the six trauma-informed principles can be applied to social media design, content moderation, and companies. We conclude by offering recommendations that balance platform responsibility and accountability with well-being and healing for all.
description: 20 pages, 2 figures. This is the author's version of the work. It is posted here for your personal use. Not for redistribution. The definitive Version of Record will be published in Proceedings of the 2023 CHI Conference on Human Factors in Computing Systems
A 3′ Exonuclease that Specifically Interacts with the 3′ End of Histone mRNA
Creators: name: Kaygun, Handan
name: Dadlez, Michal
name: Yang, Xiao-cui
name: Marzluff, William
name: Dominski, Zbigniew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: Metazoan histone mRNAs end in a highly conserved stem-loop structure followed by ACCCA. Previous studies have suggested that the stem-loop binding protein (SLBP) is the only protein binding this region. Using RNA affinity purification, we identified a second protein, designated 3'hExo, that contains a SAP and a 3' exonuclease domain and binds the same sequence. Strikingly, 3'hExo can bind the stem-loop region both separately and simultaneously with SLBP. Binding of 3'hExo requires the terminal ACCCA, whereas binding of SLBP requires the 5' side of the stem-loop region. Recombinant 3'hExo degrades RNA substrates in a 3'-5' direction and has the highest activity toward the wild-type histone mRNA. Binding of SLBP to the stem-loop at the 3' end of RNA prevents its degradation by 3'hExo. These features make 3'hExo a primary candidate for the exonuclease that initiates rapid decay of histone mRNA upon completion and/or inhibition of DNA replication.
Utilizing Symmetry of Planar Ultra-Wideband Antennas for Size Reduction and Enhanced Performance
Creators: name: Mobashsher, Ahmed Toaha
name: Abbosh, Amin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: With the increasingly new ultra wide-band applications, antenna researchers face huge challenges in designing novel operational geometries. Mono-pole and quasi-mono-pole antennas are seen to be the most compact and easily incorporate able solution for portable devices taking the advantages of printed circuit board (PCB) techniques. Most antennas of such type have symmetrical structures. It is possible to attain wider operating bandwidths by meeting symmetry conditions while chopping the antenna into halves for a compact structure. However, there is no generalized way of applying such a technique. The presented paper addresses this issue by proposing a common feeding technique that can be applied to any antenna which is miniaturized using its symmetrical structure. The proposed technique enables feeding the halved structure to achieve wider and better impedance matching than the reported full-size antennas. The theory of characteristic modes is applied to quasi-mono-pole structures to get an insight of the antennas mechanism. The radiation patterns are also correlated with modal current distributions to understand the radiation characteristics of the modified structure. Lastly, the method is implemented on some example antennas to illustrate its potential.
description: Accepted for publication in IEEE Antennas and Propagation Magazine
mAM Facilitates Conversion by ESET of Dimethyl to Trimethyl Lysine 9 of Histone H3 to Cause Transcriptional Repression
Creators: name: Cao, Ru
name: Roeder, Robert
name: Tempst, Paul
name: Wang, Hengbin
name: Chatton, Bruno
name: Zhang, Yi
name: An, Woojin
name: Xia, Li
name: Erdjument-Bromage, Hediye
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: Methylation of histone tails plays an important role in chromatin structure and function. Previously, we reported that ESET/SETDB1 is a histone methyltransferase (HMTase). Here, we show that SETDB1 tightly associates with the human homolog of mAM, a murine ATFa-associated factor. Although recombinant ESET can methylate lysine 9 of histone H3 (H3-K9), its activity is severely compromised when compared to that of the ESET/mAM complex. mAM stimulates ESET enzymatic activity by increasing the Vmax and decreasing the Km. Importantly, mAM facilitates the ESET-dependent conversion of dimethyl H3-K9 to the trimethyl state both in vitro and in vivo. Chromatin-based transcription and ChIP analyses demonstrate that mAM enhances ESET-mediated transcriptional repression in a SAM-dependent manner, and this repression correlates with H3-K9 trimethylation at the promoter. Thus, our studies establish that promoter H3-K9 trimethylation is the cause of transcriptional repression and that mAM/hAM facilitates conversion of H3-K9 dimethyl to trimethyl by ESET/SETDB1.
(100294) Elizabeth Jones
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
AKTYORNING ROL USTIDA ISHLASH MAHORATINI OSHIRISH MASALALARI
Creators: name: Perdebaeva, Nargiza
name: Qudaybergenov, Alibek
Publisher: name: Zenodo
Year: 2025

description: Teatr atalmish betakror san’atni rivojlantirish va uning sahnasida yorqin obrazlar yaratish, kelajakda bu sohani yanada rivojlantirishda yosh ustoz-mutaxassis va kadrlarning o‘rni va ahamiyati katta. Talaba-aktyorning o'z ustida ishlash xususiyatlari, uning aktyorlik mahoratini shakllantirish. Stanislavskiy ta'limotida ixtiyoriy va ixtiyorsiz diqqat.