cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
CXCR3 signaling effects on the development and immunoregulation of basal cell carcinoma and related neoplasias
Creators: name: Lo, Blanche Ka Ki
Publisher: name: University of British Columbia
Year: 2012

description: Increasing evidence has revealed that the chemokines CXCL9, CXCL10, CXCL11, and their common receptor CXCR3, are associated with tumorigenesis. Basal cell carcinoma (BCC) is a type of non-melanoma skin cancer (NMSC) and is the most common malignancy encountered. In this thesis, I hypothesized that CXCR3 signaling provides a novel marker for the growth and putative immune privilege of BCC as well as for the development of other NMSCs, such as cutaneous squamous cell carcinoma (SCC). Increased expression of chemokines CXCL10, 11 and CXCR3 was detected in cytokeratin 17 (K17)⁺ BCC cells. CXCR3/CXCL11 signaling was found to support the proliferation and survival of primary K17⁺ BCC cells derived from patient samples. Also, human BCC cells migrated in response to CXCL11 peptide in a dose-dependent manner. These findings suggest that CXCR3 signaling may be an important autocrine and/or paracrine mediator in BCC tumorigenesis. To further support the role of CXCR3 signaling in NMSC, expression of CXCR3 and its ligands were found to be significantly upregulated in cutaneous SCC and its precancerous forms (greatest in SCC). Neutralization of CXCR3 bioactivity demonstrated that CXCR3/CXCL11 signaling supported the proliferation and survival of HaCaT neoplastic keratinocyte cell cultures. Moreover, HaCaT cells transmigrated in response to CXCL11 in a dose-dependent manner. Taken together, CXCR3/ligand signaling may be important for neoplastic keratinocyte proliferation and migration, especially in cutaneous SCCs. Studies suggest BCCs exhibit immune privilege (IP), though the mechanisms have not been defined. Upregulation of a panel of IP-related genes, including IDO1, IDO2, CD200 and CD200R was identified in BCC tissues with IDO2 being expressed at the highest level. Notably, the expression and enzymatic activity of indoleamine 2,3-dioxygenase (IDO) was increased in human K17⁺ BCC cells in vitro with increased CXCR3/CXCL11 signaling. These results suggest that functional IDO is synthesized by human BCCs and may confer immunoprotection to the tumor cells, which may be enhanced by CXCR3 signaling. This thesis has revealed novel roles of CXCR3 signaling as part of the mechanism of BCC and related neoplasia development. The data may improve our understanding of NMSC pathogenesis as well as enable invention and/or modification of treatment modalities.
title: Universitätsbibliothek Marburg Ms. or. 13: XIII. L. S. Cod. A: al-Miṣbāḥ fi ʾn-naḥw
Creators: name: Muṭarrizī, Nāṣir Ibn-ʿAbd-as-Saiyid al-
Publisher: name: Philipps-Universität Marburg
Year: 2023
Subjects: Grammatik/Syntax
Sprach- und Literaturwissenschaft
Manuscripts & rare books
Handschriften, seltene Bücher

description: Elektronische Reproduktion von: [Handschrift] Universitätsbibliothek Marburg Ms. or. 13: XIII. L. S. Cod. A: al-Miṣbāḥ fi ʾn-naḥw. - 110 Blätter ; Beschreibstoff: Papier, 20 x 28 cm. - Erschienen: [Südostasien, 8./14. Jahrhundert]. - Standort: Universität Marburg, Universitätsbibliothek. - Signatur: Ms. or. 13. - Bemerkungen: Sprachen: Arabisch, Malaiisch. - Frühere Signatur: L.S. Cod. A. - Provenienz: Schröder, Johann Wilhelm (1726-1793), Schröder, Nikolaus Wilhelm (1721-1798). Ausführliche Beschreibung: Al-Toma, Adnan Jawad: Die arabischen Handschriften der Universitätsbibliothek Marburg; Marburg : Universitätsbibliothek, [1979]; S. 80-87. - Bibliographischer Nachweis: https://www.qalamos.net/receive/DE4Book_manuscript_00000013. - Digitalisiert 2023
Chaotic spin-dependent electron dynamics in a field-driven double dot potential
Creators: name: Chotorlishvili, L.
name: Toklikishvili, Z.
name: Komnik, A.
name: Berakdar, J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We study the nonlinear classical dynamics of an electron confined in a double dot potential and subjected to a spin-orbit coupling and a constant external magnetic field. It is shown that due to the spin orbit coupling, the energy can be transferred from the spin to the orbital motion. This naturally heats up the orbital motion which, due to the presence of the separatrix line in the phase space of the system, results in a motion of the electron between the dots. It is shown that depending on the strength of the spin orbit coupling and the energy of the system, the electronic orbital motion undergoes a transition from the regular to the chaotic regime.
description: 15 pages, 5 figures
Deconstructing Sentimental Stack Overflow Posts Through Interviews: Exploring the Case of Software Testing
Creators: name: Swillus, Mark
name: Zaidman, Andy
Publisher: name: arXiv
Year: 2023
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: The analysis of sentimental posts about software testing on Stack Overflow reveals that motivation and commitment of developers to use software testing methods is not only influenced by tools and technology. Rather, attitudes are also influenced by socio-technical factors. No prior studies have attempted to talk with Stack Overflow users about the sentimental posts that they write, yet, this is crucial to understand their experiences of which their post is only a fragment. As such, this study explores the precursors that make developers write sentimental posts about software testing on Stack Overflow. Through semi-structured interviews, we reconstruct the individual experiences of Stack Overflow users leading to sentimental posts about testing. We use the post as an anchor point to explore the events that lead to it and how users moved on in the meantime. Using strategies from socio-technical grounded theory (STGT), we derive hypotheses about the socio-technical factors that cause sentiment towards software testing.
description: Accepted at the CHASE 2023 Registered Reports Track
Physical Layer Security and Optimal Relay Assignment of Cooperative Autonomous Vehicles in Realistic Network Environments
Creators: name: Zhao, Yuqing
Publisher: name: Schulich School of Engineering
Year: 2023
Subjects: subject: 5G
subject: Wireless Communications
subject: Autonomous vehicles
subject: Intersections
subject: Physics--Theory
subject: Engineering
subject: Engineering--Automotive
subject: Engineering--Electronics and Electrical

description: Autonomous vehicles need to maneuver traffic infrastructures flawlessly to safely get from one destination to another. The multitude of decisions that need to be made at the intersection along with the time sensitive nature of the message results in a computationally complex challenge. The research investigates using Physical layer Security (PLS) to enhance the communication between friendly vehicles while preventing malicious eavesdropping. Keyless PLS exploits the wireless channel characteristics and provides quantifiable metrics average secrecy capacity (ASC) and signal outage probability (SOP). The environment for the communication involves cascaded Rayleigh (CR) Fading with multiple interferers, along with colluding and non-colluding eavesdroppers. This research investigates the gap when applying realistic network conditions in the investigation of SOP and ASC metrics. The research also investigates direct communication and multi-hop communication between one and more multiple friendly vehicles. The analytical methods along with an investigation into the derivation of ASC and SOP metrics with realistic characteristics and multi-hop conditions are investigated. A discussion on the comparison of the analysis and simulation are then given. Then, a method for optimal relay assignment (ORA) for cooperative communication scenarios are given along with their algorithms. The research links together multiple complex topics in the literature: CR fading, multiple interferers, multiple eavesdroppers, and multi-hop communication. It provides in-depth mathematical analysis for how one may simulate or analyze the ASC and SOP under multiple conditions. Through the investigation a case is made for using CR fading. Then, the techniques discussed in this thesis provide a robust investigation on how to ensure secure communication between autonomous vehicles. Finally, the ORA algorithm provides a deeper analysis on how vehicles may communicate to one another at the intersection. This research will benefit engineers, designers, and other stakeholders in the future of autonomous intersection management.
The vacuum induced Berry phase beyond rotating-wave approximation
Creators: name: Liu, Tao
name: Feng, Mang
name: Wang, K. L.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: With reference to the vacuum induced Berry phase (VIBP) obtained in the interaction of a spin-1/2 particle with quantized irradiation field under rotating-wave approximation (RWA), we present completely different treatment for the VIBP by a fully quantum mechanical treatment beyond the RWA, which gives a new definition of the VIBP and indicates the validity of RWA to be relevant not only to the energy conservation and comparison of characteristic parameters, but also to more subtle physics, such as the geometric property of the state evolution. Our result is of conceptual importance and also of significant relevance to quantum information processing.
title: Universitätsbibliothek Marburg Ms. or. 21: Apographa Schroederi, 2. L. S. Cod. X: Šarḥ al-Maqṣūra ad-Duraidīya ; Ms. or. 22: Apographa Schroederi, 3. L.S. Cod. Y: Nawābiġ al-Kalim
Creators: name: Ibn-Ḫālawaih, al-Ḥusain Ibn-Aḥmad
name: Zamaḫšarī, Maḥmūd Ibn-ʿUmar az-
Publisher: name: Philipps-Universität Marburg
Year: 2023
Subjects: Manuscripts & rare books
Handschriften, seltene Bücher

description: Elektronische Reproduktion von: [Handschrift] Universitätsbibliothek Marburg Ms. or. 21: Apographa Schroederi, 2. L. S. Cod. X: Šarḥ al-Maqṣūra ad-Duraidīya ; Ms. or. 22: Apographa Schroederi, 3. L.S. Cod. Y: Nawābiġ al-Kalim. - 74, 39 Seiten ; Beschreibstoff: Papier. - Erschienen: [Europa, 18. Jahrhundert]. - Standort: Universität Marburg, Universitätsbibliothek. - Signatur: Ms. or. 21 ; Ms. or. 22. - Bemerkungen: (L.S. Cod. X): Kommentar zur al-Qaṣīda al-Maqṣūra des Ibn-Duraid. Abschrift von Leiden Cod. Or. 121,2 ; (L.S. Cod. Y): Spruchsammlung. Abschrift von Leiden Cod. Or. 814,8. - Provenienz: Schröder, Johann Wilhelm (1726-1793). Ausführliche Beschreibung: Al-Toma, Adnan Jawad: Die arabischen Handschriften der Universitätsbibliothek Marburg; Marburg : Universitätsbibliothek, [1979]; S. 121-122. - Bibliographischer Nachweis: https://www.qalamos.net/receive/DE4Book_manuscript_00000033 und https://www.qalamos.net/receive/DE4Book_manuscript_00000034. - Digitalisiert 2023
Interrogating the Epigenetic Determinants of State Heterogeneity in Adult Glioblastoma
Creators: name: Nikolic, Ana
Publisher: name: Cumming School of Medicine
Year: 2023
Subjects: subject: epigenetics
subject: glioblastoma
subject: cancer
subject: cancer biology
subject: glioma
subject: GBM
subject: macroH2A
subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: Neuroscience
subject: Medicine and Surgery
subject: Pathology
subject: Biochemistry

description: Glioblastoma is the most common malignant brain tumour in adults, and prognosis remains poor, with most patients dying in a year or two despite aggressive treatment. These tumours have high degrees of intratumoral heterogeneity, with a subpopulation of cells having stem cell properties. The drivers of this stem cell phenotype are complex, and include a large number of epigenetic and genetic factors. In this thesis, I explore glioblastoma heterogeneity in two distinct ways: I use single-cell chromatin accessibility data to explore influences of copy number alterations on the glioblastoma epigenome, and I apply functional experimental techniques and genomics to characterize macroH2A2, an epigenetic regulator in this disease. In the first part of my thesis, I develop a tool for calling copy number alterations in single-cell ATAC-seq data, called CopyscAT, and show that glioblastoma tumours have limited intratumoral genetic heterogeneity. In addition, genetic subclones share similar epigenetic profiles, but with slightly different predispositions to acquiring distinct cellular states. In the second section of the thesis, I focus on the role of macroH2A2, a histone variant involved in development and cancer. I find that expression of macroH2A2 is associated with improved prognosis in glioblastoma patients, especially in patients receiving treatment. Examining existing datasets, I find that macroH2A2 expression is enriched in neural progenitor-like cells and repressed at the leading edge of tumours, and confirm this in primary patient specimens. MacroH2A2 is associated with reduced self-renewal in vitro and in vivo and knockdown of the protein increases self-renewal markers, reduces the proportion of CD44-positive cells, and shortens mouse survival. Genome-wide, macroH2A2 knockdown results in altered accessibility, with loss of early response (FOS/AP-1) motifs, which I confirm in patient-derived single-cell ATAC-seq data. Chromatin immunoprecipitation confirms that direct effects of macroH2A2 are largely repressive in nature. Lastly, a screen of epigenetic drugs identifies a compound, MI-3, capable of increasing macroH2A2 levels, and shows that macroH2A2 repression impairs sensitivity to this compound. This work contributes novel ideas to the regulation of cell states and fates in glioblastoma.
Cluster pinch-point densities in polygons
Creators: name: Flores, Steven M.
name: Kleban, Peter
name: Ziff, Robert M.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mathematical Physics (math-ph)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Probability (math.PR)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: In a statistical cluster or loop model such as percolation, or more generally the Potts models or O(n) models, a pinch point is a single bulk point where several distinct clusters or loops touch. In a polygon P harboring such a model in its interior and with 2N sides exhibiting free/fixed side-alternating boundary conditions, "boundary" clusters anchor to the fixed sides of P. At the critical point and in the continuum limit, the density (i.e., frequency of occurrence) of pinch-point events between s distinct boundary clusters at a bulk point w in P is proportional to _P. The w_i are the vertices of P, psi_1^c is a conformal field theory (CFT) corner one-leg operator, and Psi_s is a CFT bulk 2s-leg operator. In this article, we use the Coulomb gas formalism to construct explicit contour integral formulas for these correlation functions and thereby calculate the density of various pinch-point configurations at arbitrary points in the rectangle, in the hexagon, and for the case s=N, in the 2N-sided polygon at the system's critical point. Explicit formulas for these results are given in terms of algebraic functions or integrals of algebraic functions, particularly Lauricella functions. In critical percolation, the result for s=N=2 gives the density of red bonds between boundary clusters (in the continuum limit) inside a rectangle. We compare our results with high-precision simulations of critical percolation and Ising FK clusters in a rectangle of aspect ratio two and in a regular hexagon and find very good agreement.
description: 31 pages, 1 appendix, 21 figures. In the second version of this article, we have improved the organization, figures, and references that appeared in the first version
Samadinia kotakae Yan & Lee & Forges & Ng 2021, new combination
Creators: name: Yan, Bee
name: , Lee
name: Forges, Bertrand Richer De
name: Ng, Peter K. L.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Epialtidae
Samadinia
Samadinia kotakae

description: Samadinia kotakae (Takeda, 2001), new combination: Holotype: ovigerous female (18.0 × 12.6 mm) (NSMT–Cr 12935), Tosa Bay, Japan, 654–686 m, coll. Kotaka Mara, 10 December 1988. Other material: South China Sea: 1 ovigerous female (14.0 × 9.1 mm) (ZRC 2016.0079), stn CP4118, continental slope, Nanhai, 20°00.76′N 115°00.83′E to 20°01.28′N 115°02.12′E, 700–723 m, coll. NANHAI 2014 Expedition, 12 January 2014. – 5 males (17.2 × 12.0 mm, 13.1 × 8.5 mm, 12.3 × 8.0 mm, 11.2 × 7.0 mm), 1 male (16.9 × 11.2 mm) [photographed], 1 female (15.9 × 10.2 mm), 1 ovigerous female (16.8 × 11.3 mm) (ZRC 2016.0544), stn CST12, Horse Shoe Ridge, 22°0.95′N 118°53.95′E to 22°4.86′N 11°52.78′E, 1346– 758 m, coll. TW Wang, 29 April 2016. – 1 male (13.0 × 8.1 mm), 1 female (9.3 × 5.7 mm) (ZRC 2016.0545), stn CST13, Horse Shoe Ridge, 22°1.22′N 118°53.80′E to 22°6.19′N 118°52.45′E, 1,311– 816 m, coll. TW Wang, 30 April 2016. Taiwan: 1 ovigerous female (16.6 × 11.0 mm) (ZRC 2011.1055), stn CP229, 22°13.35′N 120°01.9′E, coll. 30 August 2003.
description: Published as part of Yan, Bee, Lee, Forges, Bertrand Richer De & Ng, Peter K. L., 2021, The generic affinities of the Indo-West Pacific species assigned to Rochinia A. Milne-Edwards, 1875 (Crustacea: Brachyura: Majoidea: Epialtidae), pp. 19-44 in Raffles Bulletin of Zoology 69 on page 42, DOI: 10.26107/RBZ-2021-0004, http://zenodo.org/record/5351640
Dis/Immersion in Mindfulness Meditation with a Wandering Voice Assistant
Creators: name: Ku, Bonhee
name: Itagaki, Tatsuya
name: Seaborn, Katie
Publisher: name: arXiv
Year: 2023
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Multimedia (cs.MM)
subject: Sound (cs.SD)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Mindfulness meditation is a validated means of helping people manage stress. Voice-based virtual assistants (VAs) in smart speakers, smartphones, and smart environments can assist people in carrying out mindfulness meditation through guided experiences. However, the common fixed location embodiment of VAs makes it difficult to provide intuitive support. In this work, we explored the novel embodiment of a "wandering voice" that is co-located with the user and "moves" with the task. We developed a multi-speaker VA embedded in a yoga mat that changes location along the body according to the meditation experience. We conducted a qualitative user study in two sessions, comparing a typical fixed smart speaker to the wandering VA embodiment. Thick descriptions from interviews with twelve people revealed sometimes simultaneous experiences of immersion and dis-immersion. We offer design implications for "wandering voices" and a new paradigm for VA embodiment that may extend to guidance tasks in other contexts.
description: 6 pages
Explainable AI for Software Engineering: A Systematic Review and an Empirical Study
Creators: name: Haji Mohammadkhani, Ahmad
Publisher: name: Schulich School of Engineering
Year: 2023
Subjects: subject: Computer Science

description: In recent years, leveraging machine learning (ML) techniques has become one of the main solutions to tackle many software engineering (SE) tasks, in research studies (ML4SE). This has been achieved by utilizing state-of-the-art models that tend to be more complex and black-box, such as deep learning, which is led to less explainable solutions. This lack of explainability reduces trust and uptake of ML4SE solutions by professionals in the industry. One potential remedy is to offer explainable AI (XAI) methods to provide the missing explainability. In this thesis, we aim to explore to what extent XAI has been studied in the SE domain (XAI4SE) and provide a comprehensive view of the current state-of-the-art as well as challenges and a roadmap for future work. In order to do so, we conduct a systematic literature review on 24 (out of 869 papers that were selected by keyword search) most relevant published studies in XAI4SE. Our analysis reveals that among the identified studies, software maintenance (\%68) and particularly defect prediction has the highest share on the SE stages and tasks that leverage XAI approaches. We also found that the published XAI methods are mainly applied to more classic ML models (e.g., random forest, decision trees, and regression models), rather than more complex deep learning and generative models (e.g. Transformer code models). Also, our study shows that XAI4SE is mainly used to improve the accuracy or interpretability aspects of the underlying ML models. Furthermore, we noticed a clear lack of standard evaluation metrics for XAI methods in the literature which has caused confusion among researchers and a lack of benchmarks for comparisons. To fill one of the mentioned gaps, we conduct an empirical study on the state-of-the-art Transformer-based models (CodeBERT and GraphCodeBERT) on a set of software engineering downstream tasks: code document generation (CDG), code refinement (CR), and code translation (CT). Initially, we evaluate the validity of the attention mechanism as an explainability method for each particular task. Next, through quantitative and qualitative studies, we show that CodeBERT and GraphCodeBERT learn to put attention to certain token types, depending on the downstream task. Furthermore, we show there are common patterns that cause the model to not work as expected (perform poorly while the problem at hand is easy), such as when there is a long input or when the model fails to pay proper attention to certain token types that are important for that task. Additionally, we suggest recommendations that may alleviate the observed challenges.
title: Universitätsbibliothek Marburg Ms. or. 12: XII. L.S. Cod. H: Šarḥ al-ʿAwāmil fī bayān ʿilm an-naḥw
Creators: name: Anonym
Publisher: name: Philipps-Universität Marburg
Year: 2023
Subjects: Grammatik/Syntax
Sprach- und Literaturwissenschaft
Manuscripts & rare books
Handschriften, seltene Bücher

description: Elektronische Reproduktion von: [Handschrift] Universitätsbibliothek Marburg Ms. or. 12: XII. L.S. Cod. H: Šarḥ al-ʿAwāmil fī bayān ʿilm an-naḥw. - 46 Blätter ; Beschreibstoff: Papier, 14,5 x 22 cm. - Erschienen: [Südostasien, 7./13. Jahrhundert]. - Standort: Universität Marburg, Universitätsbibliothek. - Signatur: Ms. or. 12. - Bemerkungen: Kommentar zu al-Ǧurǧānīs berühmtem Werk mit malaiischen Glossen. Sprachen: Arabisch, Malaiisch. - Frühere Signaturen: L. S. Cod. H, Codex N. - Provenienz: Schröder, Johann Wilhelm (1726-1793). Ausführliche Beschreibung: Al-Toma, Adnan Jawad: Die arabischen Handschriften der Universitätsbibliothek Marburg; Marburg : Universitätsbibliothek, [1979]; S. 75-80. - Bibliographischer Nachweis: https://www.qalamos.net/receive/DE4Book_manuscript_00000012. - Digitalisiert 2023
Asymptotic properties of ground states of scalar field equations with a vanishing parameter
Creators: name: Moroz, Vitaly
name: Muratov, Cyrill B.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We study the leading order behaviour of positive solutions of the equation -Δu +\varepsilon u-|u|^{p-2}u+|u|^{q-2}u=0,\qquad x\in\R^N, where $N\ge 3$, $q>p>2$ and when $\varepsilon>0$ is a small parameter. We give a complete characterization of all possible asymptotic regimes as a function of $p$, $q$ and $N$. The behavior of solutions depends sensitively on whether $p$ is less, equal or bigger than the critical Sobolev exponent $p^\ast=\frac{2N}{N-2}$. For $pp^\ast$ the solution asymptotically coincides with the solution of the equation with $\varepsilon=0$. In the most delicate case $p=p^\ast$ the asymptotic behaviour of the solutions is given by a particular solution of the critical Emden--Fowler equation, whose choice depends on $\varepsilon$ in a nontrivial way.
Additional file 2: of Supporting shared decision making for older people with multiple health and social care needs: a realist synthesis
Creators: name: Bunn, Frances
name: Goodman, Claire
name: Russell, Bridget
name: Wilson, Patricia
name: Manthorpe, Jill
name: Rait, Greta
name: Hodkinson, Isabel
name: Durand, Marie-Anne
Publisher: name: figshare
Year: 2018
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Table summarising details of included primary studies. (DOCX 79 kb)
Nonverbal Cues in Human-Robot Interaction: A Communication Studies Perspective
Creators: name: Urakami, Jacqueline
name: Seaborn, Katie
Publisher: name: arXiv
Year: 2023
Subjects: subject: Robotics (cs.RO)
subject: Artificial Intelligence (cs.AI)
subject: Computers and Society (cs.CY)
subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Communication between people is characterized by a broad range of nonverbal cues. Transferring these cues into the design of robots and other artificial agents that interact with people may foster more natural, inviting, and accessible experiences. In this position paper, we offer a series of definitive nonverbal codes for human-robot interaction (HRI) that address the five human sensory systems (visual, auditory, haptic, olfactory, gustatory) drawn from the field of communication studies. We discuss how these codes can be translated into design patterns for HRI using a curated sample of the communication studies and HRI literatures. As nonverbal codes are an essential mode in human communication, we argue that integrating robotic nonverbal codes in HRI will afford robots a feeling of "aliveness" or "social agency" that would otherwise be missing. We end with suggestions for research directions to stimulate work on nonverbal communication within the field of HRI and improve communication between human and robots.
description: 21 pages
Refining Inductive Types
Creators: name: Atkey, Robert
name: Johann, Patricia
name: Ghani, Neil
Publisher: name: arXiv
Year: 2012
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences
subject: D.3.3, F.3.3, D.3.1, F.3.2, F.3.1

description: Dependently typed programming languages allow sophisticated properties of data to be expressed within the type system. Of particular use in dependently typed programming are indexed types that refine data by computationally useful information. For example, the N-indexed type of vectors refines lists by their lengths. Other data types may be refined in similar ways, but programmers must produce purpose-specific refinements on an ad hoc basis, developers must anticipate which refinements to include in libraries, and implementations must often store redundant information about data and their refinements. In this paper we show how to generically derive inductive characterisations of refinements of inductive types, and argue that these characterisations can alleviate some of the aforementioned difficulties associated with ad hoc refinements. Our characterisations also ensure that standard techniques for programming with and reasoning about inductive types are applicable to refinements, and that refinements can themselves be further refined.
Development of non-invasive genomic tools for feral horses
Creators: name: Gavriliuc, Stefan Teodor
Publisher: name: Veterinary Medicine
Year: 2023
Subjects: subject: Equus ferus caballus
subject: conservation genomics
subject: non-invasive
subject: imputation
subject: Sable Island
subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Veterinary Science

description: The expansion of genomic technologies has uncovered profound insights into the physiology, etiology, demography, and treatment of disease in human and livestock populations alike. However, these advances have yet to be realized in wildlife due to the unique technical limitations inherent in these populations, including sample availability and quality. Concurrently, novel methods in genomics have been developed that are amenable for processing genetic samples obtained from wildlife. Specifically, target enrichment approaches have been developed that can amplify and genotype samples of low DNA mass, while genome imputation has been demonstrated as a viable approach for inferring missing genotype information at no incremental cost. Though these technologies may help bridge the gap between wildlife genetics and genomics, they have yet to be thoroughly validated in such populations. In this study, I tested a recently developed target enrichment approach, termed ‘Allegro Targeted Genotyping’ (ATG), as well as genome imputation in a population of free-living horses on Sable Island, Nova Scotia, Canada. For target enrichment, I evaluated the concordance between the output genotypes versus those obtained using standard genotyping approaches at the same set of genetic loci. I then determined the accuracy of genome imputation using existing genetic data from this population using different software as well as varying parameters including reference population size, initial genotype density and selection method for the initial genotypes. Genotypes from ATG were repeatable and concordant with standard genotyping panels, while imputation accuracy was generally high (>99%) and largely impacted by reference population size and initial density used for imputation. Both approaches proved successful and will help facilitate the study of population-wide genomics in Sable Island horses and may be generalizable to other wildlife study systems given further validation.
Interacting Cosmic Rays with Molecular Clouds: A Bremsstrahlung Origin of Diffuse High Energy Emission from the Inner 2deg by 1deg of the Galactic Center
Creators: name: Yusef-Zadeh, F.
name: Hewitt, J. W.
name: Wardle, M.
name: Tatischeff, V.
name: Roberts, D.
name: Cotton, W.
name: Uchiyama, H.
name: Nobukawa, M.
name: Tsuru, T. G.
name: Heinke, C.
name: Royster, M.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The high energy activity in the inner few degrees of the Galactic center is traced by diffuse radio, X-ray and gamma-ray emission. The physical relationship between different components of diffuse gas emitting at multiple wavelengths is a focus of this work. We first present radio continuum observations using Green Bank Telescope and model the nonthermal spectrum in terms of a broken power-law distribution of GeV electrons emitting synchrotron radiation. We show that the emission detected by Fermi is primarily due to nonthermal bremsstrahlung produced by the population of synchrotron emitting electrons in the GeV energy range interacting with neutral gas. The extrapolation of the electron population measured from radio data to low and high energies can also explain the origin of FeI 6.4 keV line and diffuse TeV emission, as observed with Suzaku, XMM-Newton, Chandra and the H.E.S.S. observatories. The inferred physical quantities from modeling multi-wavelength emission in the context of bremsstrahlung emission from the inner 300x120 parsecs of the Galactic center are constrained to have the cosmic ray ionization rate 1-10x10^{-15} s^-1, molecular gas heating rate elevating the gas temperature to 75-200K, fractional ionization of molecular gas 10^{-6} to 10^{-5}, large scale magnetic field 10-20 micro Gauss, the density of diffuse and dense molecular gas 100 and 10^3 cm^{-3} over 300pc and 50pc pathlengths, and the variability of FeI Kalpha 6.4 keV line emission on yearly time scales. Important implications of our study are that GeV electrons emitting in radio can explain the GeV gamma-rays detected by Fermi and that the cosmic ray irradiation model, like the model of the X-ray irradiation triggered by past activity of Sgr A*, can also explain the origin of the variable 6.4 keV emission from Galactic center molecular clouds.
description: 51 pages, 12 figures, ApJ (in press) minor changes in equations 3, 4, 6, 7
Factors associated with sexual initiation among East Asian adolescents in Canada
Creators: name: Homma, Yuko
Publisher: name: University of British Columbia
Year: 2012

description: Despite the large number of adolescents of East Asian origin in Canada, there is limited research on sexual health among this population. The primary objective of this study was to investigate factors associated with sexual initiation among East Asian adolescents in British Columbia. This dissertation consists of four studies, all of which used the British Columbia Adolescent Health Survey of 2008, including over 4,000 East Asian students in grades 7 through 12. The first study documented estimated prevalence of sexual health and risk behaviors. Nearly 10% of East Asian students had ever had sexual intercourse. Of those sexually active students, about 70% had engaged in risky sexual behaviors. Born in Canada and speaking English at home were associated with greater odds of being sexually active. The second study indicated that the Multigroup Ethnic Identity Meausre-Revised (MEIM-R) measured two highly correlated dimensions of ethnic identity (Exploration and Commitment). The MEIM-R was invariant across age groups and degree of exposure to Canadian or East Asian cultures. Using the MEIM-R, the third study examined the association between ethnic identity and sexual initiation. Students with stronger ethnic identity were less likely to have had sexual intercourse. Finally, the fourth study was conducted to identify risk and protective factors associated with sexual initiation, and to examine the likelihood of sexual initiation, given a specific set of risk and protective factors. School connectedness was a strong protective factor for boys; family connectedness, ethnic identity, and school connectedness were the top three protective factors for girls. The top three risk factors were lifetime alcohol use, sexual abuse histories, and emotional distress for boys; and lifetime alcohol use, sexual abuse histories, and looking older compared to peers of about the same age for girls. The presence of those protective factors substantially decreased the likelihood of sexual initiation for adolescents exposed to risk. For those with the three risk factors, the probability of sexual initiation was reduced by half with the addition of the top protective factor(s). The study findings suggest that a dual approach of reducing risk and fostering protection would promote sexual health among East Asian adolescents.
Electrical and Optogenetic Stimulation of Sympathetic Neurons to Stabilize Blood Pressure after Acute Spinal Cord Injury
Creators: name: Tso, Marcus
Publisher: name: Cumming School of Medicine
Year: 2023
Subjects: subject: Spinal cord injury
subject: optogenetics
subject: neuroprosthetic
subject: spinal cord
subject: sympathetic
subject: Neuroscience
subject: Medicine and Surgery
subject: Rehabilitation and Therapy
subject: Engineering--Biomedical

description: Spinal cord injury (SCI) is a life-changing condition that results in permanent motor disability and autonomic dysfunction. Acute blood pressure instability is associated with poor long term neurological recovery. Despite current clinical standards of care, blood pressure instability still occurs in the acute phase, and the in-hospital mortality of patients with acute SCI ranges up to 22%. As a result, it is important to examine the mechanisms of blood pressure control in order to identify potential future therapeutic targets for the clinical management of blood pressure instability. A recent study from our team identified regions of the spinal cord that, when stimulated with epidural electrical stimulation (EES), were able to increase blood pressure in spinal cord injured animals. This region was termed the hemodynamic hotspot. Closed-loop application of EES (eSTIM), showed success in stabilizing blood pressure in the chronic phase of SCI in rats. eSTIM induces pressor responses by activating ChAT+ sympathetic preganglionic neurons (SPNs) in the intermediolateral column that innerve the splanchnic vasculature. My thesis aimed to investigate whether blood pressure stability can be restored in mice during the acute phase of SCI using eSTIM, and to develop a method to precisely modulate blood pressure using closed-loop red-shifted optogenetic stimulation to target ChAT+ SPNs. I showed that blood pressure stability is severely disrupted following acute SCI, and that eSTIM can stabilize blood pressure and prevent blood pressure drop during orthostatic challenge in acutely injured mice. I developed a method to stimulate deeper neurons in the spinal cord hemodynamic hotspot using optogenetics and showed that the optogenetic activation of neurons at the hemodynamic hotspot was able to increase blood pressure. The closed-loop optogenetic stimulation of ChAT+ SPNs was able to stabilize blood pressure in the acute phase of SCI. The methods established in this study will pave the way for future studies that aim to investigate the roles of various spinal cord neurons in blood pressure regulation by precise modulation of specific cell subtypes.
Mixed Problems with a Parameter
Creators: name: Shlapunov, Alexander
name: Tarkhanov, Nikolai
Publisher: name: arXiv
Year: 2023
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35B25, 35J60

description: Let $X$ be a smooth $n\,$-dimensional manifold and $D$ be an open connected set in $X$ with smooth boundary $\partial D$. Perturbing the Cauchy problem for an elliptic system $Au = f$ in $D$ with data on a closed set $\iG \subset \partial D$ we obtain a family of mixed problems depending on a small parameter $\varepsilon > 0$. Although the mixed problems are subject to a non-coercive boundary condition on $\partial D \setminus \iG$ in general, each of them is uniquely solvable in an appropriate Hilbert space $\cD_{T}$ and the corresponding family $\{ u_{\varepsilon} \}$ of solutions approximates the solution of the Cauchy problem in $\cD_{T}$ whenever the solution exists. We also prove that the existence of a solution to the Cauchy problem in $\cD_{T}$ is equivalent to the boundedness of the family $\{ u_{\varepsilon} \}$. We thus derive a solvability condition for the Cauchy problem and an effective method of constructing its solution. Examples for Dirac operators in the Euclidean space $\R^n$ are considered. In the latter case we obtain a family of mixed boundary problems for the Helmholtz equation.
Row planting teff in Ethiopia: Impact on farm-level profitability and labor allocation
Creators: name: Vandercasteelen, Joachim
name: Mekdim Dereje
name: Minten, Bart
name: Alemayehu Seyoum Taffesse
Publisher: name: Gates Open Research
Year: 2019

description: Row planting teff in Ethiopia: Impact on farm-level profitability and labor allocation
Parity-violating neutron spin rotation in hydrogen and deuterium
Creators: name: Griesshammer, Harald W.
name: Schindler, Matthias R.
name: Springer, Roxanne P.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We calculate the (parity-violating) spin rotation angle of a polarized neutron beam through hydrogen and deuterium targets, using pionless effective field theory up to next-to-leading order. Our result is part of a program to obtain the five leading independent low-energy parameters that characterize hadronic parity-violation from few-body observables in one systematic and consistent framework. The two spin-rotation angles provide independent constraints on these parameters. Using naive dimensional analysis to estimate the typical size of the couplings, we expect the signal for standard target densities to be 10^-7 to 10^-6 rad/m for both hydrogen and deuterium targets. We find no indication that the nd observable is enhanced compared to the np one. All results are properly renormalized. An estimate of the numerical and systematic uncertainties of our calculations indicates excellent convergence. An appendix contains the relevant partial-wave projectors of the three-nucleon system.
description: 44 pages, 17 figures; minor corrections; to be published in EPJA
Using Machine Learning Towards Decision Support for Refractory Epilepsy Cases
Creators: name: Farhoudi, Bijan
Publisher: name: Science
Year: 2023
Subjects: subject: Epilepsy
subject: Deep Learning
subject: Machine Learning
subject: MRI
subject: Medicine and Surgery
subject: Artificial Intelligence
subject: Computer Science

description: Between 0.5% to 1.0% of people in North America suffer from epilepsy, and around 30% of patients are drug-resistant. Some drug-resistant patients are candidates for surgery and up to 60% to 70% of patients who undergo surgery become seizure-free. Finding a magnetic resonance imaging (MRI) abnormality on pre-operative imaging increases the chance of surgical success. However, up to 30% to 40% of pre-operative MRIs have no clear lesion in people with drug-resistant epilepsy, and only up to 40% to 50% of non-lesional MRI cases become seizure-free after surgery. The focus of this work was to design decision support tools to help clinicians evaluate patients for surgery. As the first step, we investigated the possibility of segregating MRIs with abnormality from MRIs without any abnormality using Deep Learning models. Such models would help clinicians when they examine MRIs to find an abnormality. Considering the value of predicting surgery results, in our next step, we explored the possibility of predicting the outcome of surgery using MRI and Deep Learning. Our results indicate that both lesional and non-lesional MRIs of patients with epilepsy contain signals that Deep Learning models can harness to predict the operative success., Finally, we explored the possibility of finding an abnormality in MRIs that were reported by radiologists as non-lesional by using Deep Learning.
Additional file 3: of Toward the precision breast cancer survival prediction utilizing combined whole genome-wide expression and somatic mutation analysis
Creators: name: Zhang, Yifan
name: Yang, William
name: Li, Dan
name: Yang, Jack
name: Guan, Renchu
name: Yang, Mary
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: The Kaplanâ Meier estimator using top 35 mutated genes. The Kaplanâ Meier curves using 35 mutated genes selected by the univariate regression as predictors displayed two very unbalanced survival risk groups. (PDF 15Â kb)
Condensate fraction of a resonant Fermi gas with spin-orbit coupling in three and two dimensions
Creators: name: Dell'Anna, L.
name: Mazzarella, G.
name: Salasnich, L.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We study the effects of laser-induced Rashba-like spin-orbit coupling along the BCS-BEC crossover of a Feshbach resonance for a two-spin-component Fermi gas. We calculate the condensate fraction in three and two dimensions and find that this quantity characterizes the crossover better than other quantities, like the chemical potential or the pairing gap. By considering both the singlet and the triplet pairings, we calculate the condensate fraction and show that a large enough spin-orbit interaction enhances the singlet condensate fraction in the BCS side while suppressing it on the BEC side.
description: 6 pages, 8 figures, accepted for publication in Phys. Rev. A
Optimizing persistent random searches
Creators: name: Tejedor, V.
name: Voituriez, R.
name: Bénichou, O.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: We consider a minimal model of persistent random searcher with short range memory. We calculate exactly for such searcher the mean first-passage time to a target in a bounded domain and find that it admits a non trivial minimum as function of the persistence length. This reveals an optimal search strategy which differs markedly from the simple ballistic motion obtained in the case of Poisson distributed targets. Our results show that the distribution of targets plays a crucial role in the random search problem. In particular, in the biologically relevant cases of either a single target or regular patterns of targets, we find that, in strong contrast with repeated statements in the literature, persistent random walks with exponential distribution of excursion lengths can minimize the search time, and in that sense perform better than any Levy walk.
description: 4 pages, 4 figures
Intercultural Musical Creation Drawing on the Theory and Practice of Turkish Models
Creators: name: Gjuka, Bahar
Publisher: name: Arts
Year: 2023
Subjects: subject: Intercultural
subject: Collaborative
subject: Research- Creation
subject: Turkish Music Models
subject: Improvisation
subject: Composition
subject: Performance Studies
subject: Child Marriage
subject: Creative Music Making
subject: Music
subject: Education
subject: Anthropology--Cultural
subject: Folklore
subject: Women's Studies

description: This study creates a new collaborative space among diverse cultures, driven by Turkish music models, and using aspects of the related rule-based improvisatory genre and process known as taksim. My work draws on historical sources to introduce the theory and practice of Turkish makam music, while using a specific methodology to enable musical creation. By doing so, I present new knowledge about collaborative music-making and performance. This work benefits from the “research-creation” approach, which removes the traditional separation between the study of music (musicology, music education) and the practices of creating music (composition, performance). By combining educational and creative methodologies with research techniques, my project presents multidisciplinary content involving music education, performance, and folklore. The project allows musicians to exchange musical ideas, acquire new techniques, compose musical parts, and expand their musical vocabulary. I analyze the musical and creative outcomes of the data created by two research-based music ensembles. Both the Sofra Ensemble and Musiki Flow were composed of Turkish and North American musicians — the first in Calgary/AB and the latter in Newnan/GA, respectively. The collaborative musicians’ musical backgrounds were combined with new information about Turkish music and its practical methods The study had a significant cultural impact on certain North American communities, allowing musicians and audiences from different cultures to come together through public concerts. By choosing to perform contemporary arrangements of traditional musical pieces, some of which dealt with sensitive social issues, my research exhibits a strong commitment to human rights. Through responsible and thoughtful advocacy my project supported children's rights, women’s empowerment, equal opportunity, and respect for diverse communities.
Cross Sections for Electron Impact Excitation of O VI Lines
Creators: name: Elabidi, Haykel
name: Sahal-Bréchot, Sylvie
name: Nessib, Nébil Ben
Publisher: name: arXiv
Year: 2011
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Radiative atomic data and electron impact excitation cross sections for the $2s-2p$ transitions in O VI for transitions among the fine structure levels belonging to the $1s^{2}nl$ ($2\leq n\leq5$) configurations have been calculated. We have extended the calculations of fine structure collision strengths up to 140 Ry and have compared our results at energies below 63 Ry to the R-matrix ones.
description: 4 pages, 4 figures