cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Pulmonary damage in Hodgkin's lymphoma patients treated with sequential chemo-radiotherapy: Predictors of radiation-induced lung injury
Creators: name: Cella, Laura
name: Liuzzi, Raffaele
name: D’Avino, Vittoria
name: Conson, Manuel
name: Picardi, Marco
name: Pugliese, Novella
name: Salvatore, Marco
name: Pacelli, Roberto
name: Biase, Angela Di
name: Solla, Raffaele
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Cancer
subject: Cell Biology
subject: Microbiology
subject: Medicine

description: Background. Our aim was to define predictors of late radiation-induced lung injury (RILI) in Hodgkin's lymphoma (HL) survivors treated with bleomycin-containing chemotherapy and radiotherapy. Material and methods. Eighty consecutive patients treated with chemotherapy and subsequent supradiaphragmatic radiation therapy for HL were retrospectively reviewed for symptoms and/or radiological signs of RILI. Median patient age was 26 years (range 14–55). Left, right, and total lung dosimetric parameters along with clinical, disease, and treatment-related characteristics were analyzed. Multivariate logistic regression analyses were performed. A receiver operator characteristic (ROC) curve analysis was performed to find possible cutoff values dividing patients into high- and low-risk groups. Results. Seven of 80 (9%) patients had lung disease at baseline. Four of 80 (5%) had toxicity after chemotherapy and before the beginning of radiotherapy. These patients were excluded from further evaluation. At a median time of 10 months (range 9–18), 9/69 patients (13%) developed lung radiological changes on computed tomography (CT) after treatment. Four of nine patients were diagnosed RTOG grade ≥ 2. On multivariate analyses, left-lung V30 (p = 0.004, OR = 1.108 95% CI 1.033–1.189) and total-lung V30 (p = 0.009, OR = 1.146 95% CI 1.035–1.270) resulted to be predictors of lung CT changes with a cutoff value of 16% and 15%, respectively. When only symptomatic RILI was considered a left-lung V30 cutoff value of 32% was estimated. Conclusion. Bleomycin and RT may cause lung injury in a small, but significant fraction of HL patients. Left-lung V30 predicts the risk of developing asymptomatic or symptomatic RILI after sequential chemo-radiotherapy.
Not "Just a Hobby": The Influence of Early Interest and Hobbies on Community College IT Student Decision-Making
Creators: name: Peterson, Eliza K.
name: Van Noy, Michelle
name: Scoville, Sam
name: Edwards, Renee
Publisher: name: Zenodo
Year: 2024
Subjects: information technology
student decision-making
community college
hobbies

description: This study aimed to find how IT-related hobbies and interests impacted students’ educational and career decision-making. Methods: As part of a six-year-long, ATE-funded study of IT students at Ivy Tech Community College, our team conducted semi-structured, phenomenological interviews. These interviews were analyzed using keyword searches and a combined inductive-deductive approach to coding to explore how IT-related hobbies and interests interacted with other personal characteristics to inform student decision-making. Findings: Our team identified a potential link between early IT interest, IT-related hobbies, and persistence in IT education and careers. Many participants in the study had a moment of clarity where they realized that their IT hobby could become their career, the “hobby-to-career reckoning.” Contributions: This piece explores the potential connection between IT interests/hobbies and student outcomes within the field of IT while exploring the different social factors that may impact student decision-making and the role of the hobby-to-career reckoning in the decision-making process. This piece will give practitioners and researchers insight into how early interest in IT and IT-related hobbies may impact student decision-making about IT educational programs and careers.
Grapevine trunk disease in German viticulture IV. Spreading of spores of the Esca related fungus Phaeomoniella chlamydospora and the occurrence of foliar Esca-symptoms in German vineyards
Creators: name: Molnar, M.
name: Voegele, R. T.
name: Fischer, M.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2020

description: The anamorphic fungus Phaeomoniella chlamydospora (Pch), related to Grapevine trunk diseases (GTDs) such as "Petri disease" and Esca, was originally restricted to the Mediterranean area but can now be found worldwide. GTDs are the most destructive diseases in vineyards causing high losses every year. As there are no effective fungicides available it is important to understand the epidemiology of this fungus. To investigate the occurrence and distribution of Pch in the field, spore traps were placed in two selected vineyards located at the Julius Kühn-Institut (JKI) in Siebeldingen, Germany, for three consecutive years. Plots were planted with cultivars 'Chardonnay' and the fungus resistant cultivar 'Phoenix'. Analysis of the traps was performed by a specifically developed nested-PCR approach. As a result it was proven that Pch is present in the vineyards throughout the whole year, including wintertime. The occurrence of Pch conidia during the winter months is a central issue as the annual pruning of vines is done in the winter season and pruning wounds are supposed to be the main entry point for this pathogen. During the three year survey also symptom appearance, both chronic and apoplectic, on leaves as well as weather conditions have been recorded. Symptoms were evident in both vineyards; however, no clear correlation was obtained between symptoms and spore flight. High temperatures combined with low humidity may have a negative impact on spore dispersal, while cold temperatures such as in wintertime have no negative effect on the appearance of spores.
description: VITIS - Journal of Grapevine Research, Vol. 59 No. 2 (2020): Vitis
Cancer incidence and radiation therapy in Mozambique – a comparative study to Sweden
Creators: name: Matias, Lucílio Dos S.
name: Lind, Bengt K.
name: Maphossa, Alexandre M.
name: Gudowska, Irena
name: Toma-Dasu, Iuliana
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Hematology
subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biotechnology
subject: Microbiology
subject: FOS: Biological sciences
subject: Medicine
subject: Engineering

description: Cancer incidence and radiation therapy in Mozambique – a comparative study to Sweden
Towards individualized dose constraints: Adjusting the QUANTEC radiation pneumonitis model for clinical risk factors
Creators: name: Vogelius, Ivan R.
name: Farr, Katherina P.
name: Azza A. Khalil
name: Bentzen, Søren M.
name: Appelt, Ane L.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Computational Biology
subject: Cancer
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biotechnology
subject: Medicine

description: Background. Understanding the dose-response of the lung in order to minimize the risk of radiation pneumonitis (RP) is critical for optimization of lung cancer radiotherapy. We propose a method to combine the dose-response relationship for RP in the landmark QUANTEC paper with known clinical risk factors, in order to enable individual risk prediction. The approach is validated in an independent dataset. Material and methods. The prevalence of risk factors in the patient populations underlying the QUANTEC analysis was estimated, and a previously published method to adjust dose-response relationships for clinical risk factors was employed. Effect size estimates (odds ratios) for risk factors were drawn from a recently published meta-analysis. Baseline values for D50 and γ50 were found. The method was tested in an independent dataset (103 patients), comparing the predictive power of the dose-only QUANTEC model and the model including risk factors. Subdistribution cumulative incidence functions were compared for patients with high/low-risk predictions from the two models, and concordance indices (c-indices) for the prediction of RP were calculated. Results. The reference dose- response relationship for a patient without pulmonary co-morbidities, caudally located tumor, no history of smoking, < 63 years old, and receiving no sequential chemotherapy was estimated as D500 = 34.4 Gy (95% CI 30.7, 38.9), γ500 = 1.19 (95% CI 1.00, 1.43). Individual patient risk estimates were calculated. The cumulative incidences of RP in the validation dataset were not significantly different in high/low-risk patients when doing risk allocation with the QUANTEC model (p = 0.11), but were significantly different using the individualized model (p = 0.006). C-indices were significantly different between the dose-only and the individualized model. Conclusion. This study presents a method to combine a published dose-response function with known clinical risk factors and demonstrates the increased predictive power of the combined model. The method allows for individualization of dose constraints and individual patient risk estimates.
Influence of grape juice extraction methods on basic analytical parameters
Creators: name: Dumas, V.
name: Saurin, N.
name: Destrac Irvine, A.
name: Dedet, S.
name: Veyret, M.
name: Marchal, C.
name: Ojeda, H.
name: Van Leeuwen, C.
name: Duchêne, E.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2020

description: Currently, for monitoring the ripening of grape berries, different devices are used to produce the juices to be analysed. Crushing the berries is a key step that determines the quantity of juice extracted and may impact it composition. The effect of different devices on analytical parameters of the musts produced were compared in this study. Samples from four grape varieties ('Cabernet-Sauvignon', 'Ekigaïna', 'Marselan' and 'Vermentino'), showing a variability of berry size and precocity, were crushed using six different devices (ASieves, Bag mixer®, Crusher, Manual, TPress and Blender). Whatever the pressing equipment, sugar concentrations of the must were not modified by the extraction method, unlike other parameters. pH and titratable acidity were slightly impacted by the crushing method without changing the ranking of the varieties. However, potassium concentrations were more impacted by the pressing method. Differences in mechanical forces applied to skins and seeds according to the pressing equipment used may release more or less potassium. This study clearly discarded a complete grinding of the samples for grape ripening monitoring: this method strongly modified the potassium content and, consequently, the pH and the titratable acidity of the musts.
description: VITIS - Journal of Grapevine Research, Vol. 59 No. 2 (2020): Vitis
Is there an impact of heart exposure on the incidence of radiation pneumonitis? Analysis of data from a large clinical cohort
Creators: name: Tucker, Susan L.
name: Zhongxing Liao
name: Dinh, Jeffrey
name: Grosshans, David R.
name: Bian, Shelly X.
name: Radhe Mohan
name: Martel, Mary K.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Cancer
subject: Developmental Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Biotechnology
subject: Pharmacology
subject: Molecular Biology
subject: Cell Biology
subject: Medicine
subject: Physics
subject: Biophysics

description: Background. The goal of the present study was to determine, in a large clinical cohort, whether incidental radiation exposure to the heart during definitive radiotherapy of inoperable non-small cell lung cancer (NSCLC) detectably increased the risk of radiation pneumonitis (RP) beyond that resulting from radiation exposure to lung. Material and methods. Data were analyzed from all patients who received definitive three-dimensional (3D) concurrent radiotherapy or intensity-modulated radiotherapy for the treatment of NSCLC over a 10-year period at our institution, except those who had previous lung cancer or for whom radiation treatment plans were unavailable for calculation of heart and lung dose-volume histograms (DVHs). Parameters computed from heart and lung DVHs included mean lung dose (MLD), effective lung dose computed using volume parameter n = 0.5 (Deff), mean heart dose (MHD), percentage of heart receiving > 65 Gy (V65), and minimum dose to the hottest 10% of heart (D10). Univariate and multivariate normal-tissue complication probability (NTCP) models were used to analyze incidence of Grade ≥ 2 or Grade ≥ 3 RP as a function of these and other parameters. Results. The study cohort included 629 patients, with crude rates of Grade ≥ 2 RP and Grade ≥ 3 RP of N = 263 (42%) and N = 124 (20%), respectively. Univariate NTCP models based on dosimetric lung parameters (MLD and Deff) fit the data better than models based on univariate heart parameters (heart D10, heart V65 or MHD). In multivariate modeling, incorporation of heart parameters did not significantly improve the fit of RP risk models based on lung parameters alone (p > 0.38 in each case). Conclusions. In this large clinical cohort, there was no evidence that incidental heart exposure during radiotherapy of NSCLC had a detectable impact on the occurrence of moderate or severe RP.
title: Umo dara
title: What I will do tomorrow
titleType: AlternativeTitle
Creators: name: Velásquez, Moisés
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: Kibiri
subject: prm

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
description: Kakoro says what he will do the following day: looking for firewood and sago in the bush, and then coming back home
Lab tech (Medical illustrations)
Creators: name: Francone, Clarice Ashworth
Publisher: name: Oregon Health & Science University
Year: 0
Subjects: Medical Illustration
Equipment and Supplies
Laboratories
Clinical Laboratory Techniques
Biopsy
Gastric Lavage
Blood Specimen Collection
Liquid Biopsy

description: Labeled pencil sketches of various pieces of medical laboratory equipment. Also includes depictions of how instruments are used on patients to collect samples.
Efficacy of kaolin treatments against Drosophila suzukii and their impact on the composition and taste of processed wines
Creators: name: Linder, C.
name: Rösti, J.
name: Lorenzini, F.
name: Deneulin, P.
name: Badertscher, R.
name: Kehrli, P.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2020

description: Drosophila suzukii is a very polyphagous species that can also tack and develop in a great variety of grape cultivars. In Switzerland, the control of D. suzukii mainly relies on prophylactic measures and kaolin, a white inert aluminosilicate mineral who's particles stick to the leaf surface and form a physical barrier that help to reduce ovipositions by the pest. Here we present a synthesis of our recent insights on the efficacy of kaolin against D. suzukii as well as on the chemical and sensory properties of the wines vinified from kaolin treated grapes. In autumn 2016, kaolin (Surround WP®) was applied in 23 field trials on various cultivars located in various winegrowing regions of Switzerland. Overall, kaolin achieved an average efficiency of 54 % and no significant differences could be observed between kaolin applications at 1 % and 2 % with 56.8 % and 57.1 % efficacy, respectively. At the higher concentration, the preventive and curative strategy were also nearly as effective with efficacies at 67.4 % and 50.3 %, respectively. In addition, a field experiment was set up on the red grape cultivar 'Mara' in 2015. This experiment revealed that three applications of kaolin at 1 % or 2 % did neither affect fermentation nor the usual chemical properties of kaolin treated wines compared to the untreated control. However, aluminum concentration within wines increased with the applied dosage of kaolin but the measured aluminum levels were 38-times lower than the maximal German threshold of 8 mg·L-1. Moreover, tasters were also not able to distinguish the aroma and the taste of wines processed from kaolin treated grapes from the untreated control. We therefore conclude that kaolin applications are effective against D. suzukii and do not cause any major risks to the environment, to wine quality and to human health.
description: VITIS - Journal of Grapevine Research, Vol. 59 No. 2 (2020): Vitis
Dynamics of Scaphoideus titanus population in southern South Tyrol (Italy) and detection of Grapevine Flavescence Dorée phytoplasma in the insect with a multiplex real-time PCR
Creators: name: Gallmetzer, A.
name: Innerebner, G.
name: Roschatt, C.
name: Reyes-Domínguez, Y.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2020

description: In South Tyrol the population of Scaphoideus titanus, the vector of Grapevine Flavescence dorée phytoplasma (FD), has been steadily increasing since 2010. The present work provides an overview of the monitoring activity of Scaphoideus titanus in South Tyrolean vineyards coupled with the description of a sensitive and reliable detection method of FD in the insect vector. We have developed an endogenous control of Scaphoideus titanus to be used in a multiplex real-time PCR, amplifying the map gene of FD phytoplasma. We present evidence on the performance of this new vector reference and its compatibility with FD detection.
description: VITIS - Journal of Grapevine Research, Vol. 59 No. 2 (2020): Vitis
Contrasting adaptation of xylem to dehydration in two Vitis vinifera L. sub-species
Creators: name: Pouzoulet, J.
name: Pivovaroff, A. L.
name: Scudiero, E.
name: De Guzman, M. E.
name: Rolshausen, P. E.
name: Santiago, L. S.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2020

description: Xylem hydraulic properties of agricultural crop species can be linked to their region of origin, but because crop systems are often irrigated to reach optimum quality and yield, key differences in drought resistance are not often considered. We investigated how hydraulic conductivity and xylem vulnerability to drought-induced cavitation of two grapevine cultivars correspond to their centers of domestication with 'Merlot' (Vitis vinifera subspecies occidentalis) having been domesticated in a temperate forest region, and 'Thompson Seedless' (Vitis vinifera subspecies orientalis) domesticated in a semi-arid region. We used anatomical measurements and xylem vulnerability curves to evaluate hydraulic traits and drought resistance. Our results showed that 'Thompson Seedless' was significantly more vulnerable to drought-induced cavitation than 'Merlot'. Bench dehydration produced significantly different estimations of xylem vulnerability to cavitation in each cultivar. This result was consistent with anatomical measurement, with 'Thompson Seedless' stems having greater maximum stem-specific hydraulic conductivity, more vessels, higher vessel density and a greater lumen fraction than 'Merlot'. The relatively large amount of xylem vessels and lumen area in 'Thompson Seedless' is consistent with domestication in a semi-arid habitat where a greater number and size diversity of xylem vessels would be needed to transport water and meet evaporative demand as opposed to cultivars that were domesticated in temperate forest regions like 'Merlot'. These differences appear to expose 'Thompson Seedless' to high xylem vulnerability to cavitation.
description: VITIS - Journal of Grapevine Research, Vol. 59 No. 2 (2020): Vitis
'Kunbarat' and 'Kunleany' – full not half-siblings
Creators: name: Müllner, S.
name: Röckel, F.
name: Maul, E.
name: Zyprian, E.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2020

description: Research Note
description: VITIS - Journal of Grapevine Research, Vol. 59 No. 2 (2020): Vitis
Potassium fertilization in relation to downy mildew disease incidence in grape leaves
Creators: name: Pushpavathi, Y.
name: Satisha, J.
name: Shivashankara, K. S.
name: Satisha, G. C.
name: Sriram, S.
name: Lakshminarayana Reddy, M. L.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2020

description: Influence of different sources of potassium and their method of application was studied on incidence of downy mildew infection in grape leaves of 'Sharad Seedless' (syn: 'Kishmish Chorni'). The total phenolic content and individual phenolic acids were analysed from healthy and downy mildew infected leaves of 'Sharad Seedless' and the degree of downy mildew infection was well correlated with potassium content in the petioles. Different sources and method of potassium application had significant effect on Phenylalanine ammonia-lyase (PAL) enzyme activity and preformed phenols in healthy vines. Significant increase in PAL enzyme activity, total phenols and individual phenolic acids was registered with increase in disease severity. Magnitude of percent change in PAL enzyme activity and total phenolic content was highest in vines with maximum disease infection. Among the phenolic acids, o-Coumaric acid, p-Coumaric acid have a definite role in disease resistance. We could also observe the variation in disease severity in vines which received different sources of potassium which was supplied in different quantities whether through soil and/or through fertigation.
description: VITIS - Journal of Grapevine Research, Vol. 59 No. 2 (2020): Vitis
Assessing patients’ perceived bother from the gastrointestinal side effects of radiotherapy for localized prostate cancer: Initial questionnaire development and validation
Creators: name: Turesson, Ingela
name: Persson, Christina
name: Pettersson, Anna
name: Johansson, Birgitta
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Science Policy
Biological Sciences
Medicine
Engineering

description: Background. The present study reports on the development and first steps of validation of the Gastrointestinal Side Effects Questionnaire (GISEQ), a measure of patient-reported gastrointestinal symptoms following local radiotherapy to the prostate. The questionnaire design provides a novel approach of assessment of side effects of prostate radiotherapy, by enabling measurement of patient-perceived change in symptoms. Material and methods. The eight-item GISEQ was administered to 130 prostate cancer patients referred to radiotherapy. Patients completed the GISEQ at four, eight and 15 weeks after start of radiotherapy. The psychometric properties including validity, reliability, responsiveness and feasibility were evaluated. The EORTC QLQ-C30 and QLQ-PR25 were chosen as comparative measures. Results. Expert opinion supported content validity. For concurrent validity, correlation between the GISEQ and matching items in the EORTC questionnaires was moderate but significant (r > 0.41, p < 0.001). The responsiveness was adequate, indicated by changes in GISEQ scores over time corresponding to the effects of radiation. Internal consistency was satisfactory (overall Cronbach's α> 0.70). Sensitivity and specificity for items diarrhea, constipation and blood in stools ranged from 50% to 100% and from 68% to 100%, respectively. All items had a floor effect above 15%. The response rates ranged from 85% to 92% and missing items was < 0.8%, indicating good feasibility. Conclusions. The GISEQ showed satisfactory internal consistency and adequate content validity, concurrent validity and responsiveness. It is brief, easy to use and can be quickly evaluated, making it useful not only for research but possibly also for clinical settings. Modification of response scale and extension of items are potential improvements. Further work is needed to strengthen the psychometric qualities of the GISEQ and to evaluate its clinical use and potential effects of response shift and recall bias.
Partnership status affects the association between gastrointestinal symptoms and quality of life after radiation therapy for prostate cancer
Creators: name: Alsadius, David
name: Olsson, Caroline
name: Steineck, Gunnar
name: Wilderäng, Ulrica
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Hematology
Science Policy
Cancer
Biological Sciences
Biotechnology
Pharmacology
Medicine

description: Purpose. To study if partnership modifies the effect of gastrointestinal symptoms on quality of life after radiation therapy for prostate cancer. Material and methods. Using a study-specific questionnaire we conducted a cross-sectional follow-up of the occurrence gastrointestinal symptoms and quality of life after radiation therapy for prostate cancer. We obtained information from 874 prostate cancer survivors treated with radiation therapy at the Sahlgrenska University Hospital, Sweden between 1994 and 2006. In this paper we describe how partnership status affects the association between gastrointestinal symptoms and quality of life. Results. We found that unpartnered men with gastrointestinal symptoms reported a lower quality of life than unpartnered men without such symptoms. Unpartnered men with symptoms had an excess risk of low quality of life compared with unpartnered men without symptoms for those experiencing altered composition of stools, prevalence ratio 3.8 (95% CI 1.1–13.1), leakage, 3.6 (1.3–10.1), sensory bowel symptoms, 4.5 (1.6–12.8), and for urgency, 4.2 (1.2–15.1). We also found that unpartnered men with symptoms had an excess risk of low quality of life compared with partnered men with symptoms for those experiencing altered composition of stools, prevalence ratio 2.9 (95% CI 1.4–5.8), leakage 2.8 (1.2–6.4), sensory bowel symptoms 3.4 (1.5–7.4), urgency 2.6 (1.2–5.8), and for any gastrointestinal symptom 2.5 (1.3–4.9). Conclusion. Unpartnered men may represent a group that is specifically vulnerable to the distressful effects of gastrointestinal symptoms after radiation therapy for prostate cancer.
Four-dimensional dose evaluation of inhomogeneous dose distributions planned for non-small cell lung cancer patients with lymph node involvement
Creators: name: Brink, Carsten
name: Nielsen, Tine B.
name: Olfred Hansen
name: Schytte, Tine
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Hematology
subject: Cancer
subject: Mathematics
subject: FOS: Mathematics
subject: Immunology
subject: FOS: Clinical medicine
subject: Pharmacology
subject: Physiology
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Medicine
subject: Physics

description: Four-dimensional dose evaluation of inhomogeneous dose distributions planned for non-small cell lung cancer patients with lymph node involvement
Plataforma Lattes: Passo a passo para construir e atualizar seu currículo acadêmico
Creators: name: Prates, Guilherme Kayser
name: Castro, Gisele Lopes
name: Maciel Junior, Paulo Ricardo Costa
name: Souza, Luccas Melo de
name: Paz, Adriana Aparecida
Publisher: name: Zenodo
Year: 2024
Subjects: CurriculoLattes
pesquisa
tecnologia
inovação
workshop
enfermagem
carreira
pesquisador

description: O Currículo Lattes é um padrão de registro para pesquisadores e profissionais acadêmicos no Brasil, sendo amplamente utilizado para avaliações de bolsas, auxílios à pesquisa, seleções e progressões de carreira. Saber preenchê-lo corretamente é fundamental para garantir o reconhecimento das suas qualificações e atividades. O objetivo é capacitar os participantes para preencher, organizar e manter seus currículos na Plataforma Lattes de forma correta e estratégica, garantindo ques suas produções técnicas e científicas seja registradas de maneira completa e adequada.
The effect of a geriatric evaluation on treatment decisions for older cancer patients – a systematic review
Creators: name: Munster, Barbara C. Van
name: Hamaker, Marije E.
name: Anandi H. Schiphorst
name: Huinink, Daan Ten Bokkel
name: Schaar, Cees
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Computational Biology
Science Policy
Cancer
Biological Sciences
Earth and Environmental Sciences
Biotechnology
Medicine

description: Aim. The aim of this systematic review is to summarise all available data on the effect of a geriatric evaluation on the multidisciplinary treatment of older cancer patients, focussing on oncologic treatment decisions and the implementation of non-oncologic interventions. Methods. A systematic search in MEDLINE and EMBASE for studies on the effect of a geriatric evaluation on oncologic and non-oncologic treatment for older cancer patients. Results. Literature search identified 1654 reports (624 from Medline and 1030 from Embase), of which 10 studies were included in the review. Three studies used a geriatric consultation while seven used a geriatric assessment performed by a cancer specialist, healthcare worker or (research) nurse. Six studies addressed a change in oncologic treatment, the initial treatment plan was modified in a median of 39% of patients after geriatric evaluation, of which two thirds resulted in less intensive treatment. Seven studies focused on the implementation of non-oncologic interventions based on the results of the geriatric evaluation; all but one reported that interventions were suggested for over 70% of patients, even in studies that did not focus specifically on frail older patients. In the other study, implementation of non-oncologic interventions was left to the cancer specialist's discretion. Conclusion. A geriatric evaluation has significant impact on oncologic and non-oncologic treatment decisions in older cancer patients and deserves consideration in the oncologic work-up for these patients.
title: A comparison of atmospheric CO2 capture with steel slags in Mexico and the United Kingdom
Creators: name: Del Angel Lozano, Jose Porfirio
Publisher: name: University of Glasgow
Year: 2024

description: The continuous increase of greenhouse gas emissions, particularly CO2, has prompted con-siderable concern and research towards decreasing their impact within the environment. Ef-forts to reduce CO2 emissions have been developed with the aim of avoiding further increases in global temperature, one of the main repercussions of increased greenhouse gas emissions, and affecting the planetary balance. From this, carbon capture and storage, through mineral carbonation using iron and steel slags, could represent a solution for CO2 emissions offsetting, while also repurposing of an industrial waste material.

The research work described within this thesis aims to address the environmental challenges related to excessive atmospheric CO2, by investigating carbon removal strategies, focusing on the utilisation of iron and steel manufacturing slags for CO2 sequestration, while efficiently repurposing industrial waste. The research will be structured around three main objectives. Firstly, it will assess the CO2 capturing rates of legacy slags from Monclova, Mexico, and Ra-venscraig, Scotland, using x-ray tomography and 3D data analysis. Secondly, it will estimate the volume of legacy iron and steel slags in Mexico through mapping former and current steelmaking locations, to calculate the CO2 sequestration capacity of the country. Thirdly, it will evaluate the cementitious properties of legacy slags from England, Mexico, and Scotland for potential reutilization in sustainable concrete production. Through chapters II, III, and IV, the thesis aims to extend the understanding of mineral carbonation of iron and steel manufac-turing slags to mitigate carbon dioxide emissions.

This research highlighted the key role of humidity along passive mineralisation of CO2 within slag heaps, as the amount of carbonated CO2 quantified in Scottish slags was double that of Mexican slags. Within the 273 K tonnes of slags stockpiled across Mexico, 5.7 K tonnes of CO2 have been mineralised; and there is an estimated potential of 160 K tonnes of CO2 that can be captured through enhanced carbonation. Potential pozzolanic behaviour were found in legacy iron and steel slags from England, Mexico and Scotland, where Blast Furnace and Basic Oxygen Furnace slags showed higher reactivity than Electric Arc Furnace slags, how-ever further research is needed to determined their capacity to be used as replacement for Ordinary Portland Cement. The findings from this research aim to extend the understanding on iron and steel slags and their wider use for environmental remediation and a source of materials for various industrial fields, not only correlated to steel manufacturing.
Using group model building to frame the commercial determinants of dietary behaviour in adolescence – proposed methods for online system mapping workshops
Creators: name: Chavez-Ugalde, Yanaina
name: Toumpakari, Zoi
name: White, Martin
name: De Vocht, Frank
name: Jago, Russell
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Research
Group Model Building
Online workshops
Adolescence
System mapping
Public health
Dietary behaviour
Causal loop diagram

description: Abstract: Background: Group model building (GMB) is a participatory approach whereby diverse stakeholders can share their views about a problem to create a collective understanding of a complex system. In this article we report our methodological approach to adapt face-to-face GMB processes to an online format to explore the mechanisms by which commercial drivers influence adolescents’ dietary behaviour. We use our experiences to make recommendations on how online GMB could be delivered. Methods: We planned, adapted, piloted, delivered, and evaluated a series of online GMB workshops with adolescents, policymakers and public health practitioners to create a system map of the commercial determinants of dietary behaviour in adolescence. We adapted face-to-face GMB workshops to a series of 3 online GMB workshops with 11 adolescents (16–18 years) living in the Southwest of England, and one GMB workshop with policymakers and public health practitioners. Results: In our experience, adapting, and delivering GMB online is feasible, engaging, cost-saving and an enjoyable experience. Participants gave positive feedback in terms of engagement and enjoyment, and it allowed them to recognise different points of view about the same problem. Participants became familiarised with system thinking and system dynamics concepts, developed a shared understanding of a complex issue and portrayed it in a system map that depicted the most important factors in a causal structure as well as their interactions at various levels. Conclusions: We recommend using process mapping to understand the overall GMB process in an online environment and piloting the workshops to test the timings and flow between online platforms. For facilitation and delivery, facilitators need to ensure they can create an inviting and engaging online environment, even for participants who decide to have their cameras off. Separating GMB activities into different workshops allowed participants to reflect on the problem being discussed and bring new ideas to subsequent workshops. Evaluating the workshops enabled us to build evidence on the trade-offs between the effectiveness, quality and efficiency of online GMB workshops, and how this might be enhanced to identify leverage points and achieve systemic changes in complex issues. Ethical approval: The research was approved by the University of Bristol’s Faculty of Health Sciences Research Ethics Committee (Ref: 99,003) and written consent was received from all participants.
A study of patients not registered in the Swedish cancer register but reported to the Swedish register of palliative care 2009 as deceased due to cancer
Creators: name: Nilsson, Martin
name: Tavelin, Björn
name: Axelsson, Bertil
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Computational Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Cancer
subject: Developmental Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Meta Science
subject: Cell Biology

description: Background. The Swedish Cancer Register (SCR), an old and reputable health data register, contributes a large amount of data used in research. The quality of the research using SCR data depends on the completeness and validity of the register. In Sweden, every healthcare provider is obligated to report newly detected cases of cancer to the SCR regardless of the diagnostic basis. This study aimed to clarify whether there is an under-reporting of patients with cancer to the SCR or an over-reporting of cancer as cause of death to the SRPC as all patients do not appear in both registers. In addition, this study looked at the distribution of under-reporting or over-reporting related to age, sex, type of cancer, diagnostic basis, and department responsible for cancer diagnosis. Material and methods. Of the 10 559 patients whose cause of death was cancer as reported to the SRPC (2009), 1394 patients (13.2%) were not registered in the SCR (1958–2009). Medical records from a representative sample of 203 patients were collected and reviewed. Results. The medical records for 193 patients were obtained; of those, 183 (95%) patients should have been reported to the SCR. Among these, radiologic investigation was the most common basis for diagnosis and there was a significant over-representation of cancer of the pancreas, lung, liver, and bile ducts. Discussion. This study cannot quantify the completeness of the SCR. The findings indicate that 12.5% of patients dying of cancer in palliative care are not reported, that specialized hospital departments diagnose the vast majority of the unreported patients, and that routines for how to report patients to the SCR based on radiological findings should be revised.
Hepatocellular carcinoma treated by sorafenib with complete radiological response according to mRECIST criteria: Could we stop the treatment? About four cases
Creators: name: Jean-Frédéric Blanc
name: Poullenot, Florian
name: Bioulac-Sage, Paulette
name: Laumonier, Hervé
name: Saric, Jean
name: Carteret, Thibault
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Cancer
subject: Immunology
subject: FOS: Clinical medicine
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Medicine

description: Hepatocellular carcinoma treated by sorafenib with complete radiological response according to mRECIST criteria: Could we stop the treatment? About four cases
Gastrointestinal consequences of cancer treatment and the wider context: A bad gut feeling
Creators: name: Muls, Ann Cecile
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Cancer
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Biotechnology
subject: Medicine

description: Background. The percentage of people living with a diagnosis of cancer is rising globally. Between 20% and 25% of people treated for cancer experience a consequence of cancer which has an adverse impact on the quality of their life. Gastrointestinal (GI) symptoms are the most common of all consequences of cancer treatment and have the greatest impact on daily activity.Pathophysiology of long-term bowel damage after pelvic radiotherapy. Long-term damage to the bowel after radiotherapy is mediated by ischaemic changes and fibrosis. Each fraction of radiotherapy causes a series of repetitive injuries to the intestinal tissue resulting in an altered healing process, which affects the integrity of the repair and changes the architecture of the bowel wall.The nature of GI symptoms that develop. Patient-reported outcome measures show that diarrhoea, urgency, increased bowel frequency, tenesmus and flatulence are the five most prevalent GI symptoms with a moderate or severe impact on patients’ daily lives after treatment with pelvic radiotherapy. Many patients also experience fatigue, urinary problems and have sexual concerns.Systematic assessment and management. The complex nature of those symptoms warrants systematic assessment and management. The use of a tested algorithm can assist in achieving this. The most common contributing factors to ongoing bowel problems after pelvic radiotherapy are small intestinal bacterial overgrowth, bile acid malabsorption, pancreatic insufficiency, rectal bleeding and its impact on bone health.The wider context. Symptom burden, socio-psychosocial impact, memory and cognitive function, fatigue, urinary problems and sexual concerns need to be taken into account when thinking about consequences of cancer treatment.Conclusion. As our understanding of consequences of cancer treatments continues to emerge and encompass a wide variety of specialties, a holistic, multifaceted and multidisciplinary approach is required to manage those consequences long-term.
Individual project on theme "Hirundo Linnaeus" (MOOC: CompTech in biology)
Creators: name: Kulshin Anton
Publisher: name: Zenodo
Year: 2022

description: Данный кейс является результатом реализации индивидуального проекта Кульшина Антона по теме "Hirundo Linnaeus" в рамках онлайн курса "Компьютерные технологии в биологии" (автор – А.В. Ваганов) (https://stepik.org/course/60859/promo)
Chemotherapy as palliative treatment for peritoneal carcinomatosis of gastric origin
Creators: name: Thomassen, Irene
name: Bernards, Nienke
name: Gestel, Yvette R. Van
name: Geert-Jan Creemers
name: Jacobs, Esther M.
name: Lemmens, Valery E.
name: Hingh, Ignace H. De
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: Cancer
subject: Marine Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Biochemistry

description: Chemotherapy as palliative treatment for peritoneal carcinomatosis of gastric origin
Comparison of three immobilisation systems for radiation therapy in head and neck cancer
Creators: name: Johansen, Jørgen
name: Brink, Carsten
name: Hansen, Christian Rønn
name: Christiansen, Rasmus Lübeck
name: Nielsen, Tine Bjørn
name: Bertelsen, Anders Smedegaard
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Biological Sciences
subject: Biotechnology
subject: Medicine
subject: Physics
subject: Engineering

description: Comparison of three immobilisation systems for radiation therapy in head and neck cancer
Breast (Medical illustrations)
Creators: name: Francone, Clarice Ashworth
Publisher: name: Oregon Health & Science University
Year: 0
Subjects: Medical Illustration
Breast
Breast Neoplasms
Mastectomy
Thoracic Wall
Pectoralis Muscles

description: Unlabeled pencil sketches depicting the muscular structure under a breast, the skeletal structure under a breast and the aftermath of a mastectomy.
Pathophysiology of late anorectal dysfunction following external beam radiotherapy for prostate cancer
Creators: name: Petersen, Stine E.
name: Laurberg, Søren
name: Drewes, Asbjørn M.
name: Krogh, Klaus
name: Høyer, Morten
name: Bregendahl, Sidse
name: Langschwager, Maria
name: Brock, Christina
name: Lundby, Lilli
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Hematology
subject: Science Policy
subject: Cancer
subject: Developmental Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Sociology
subject: FOS: Sociology
subject: Cell Biology
subject: Medicine

description: Background. Patients treated with external beam radiotherapy (EBRT) may suffer from long-term anorectal adverse effects. The purpose of the present study was to assess long-term functional and structural anorectal changes in patients previously treated with EBRT for prostate cancer and to suggest the mechanism behind the development of the adverse effects.Material and methods. Our previously proposed RT-induced anorectal dysfunction (RT-ARD) score, developed with the intention to survey anorectal dysfunction was used to identify patients with and without anorectal symptoms. Among 309 patients surveyed with the questionnaire, we chose 23 patients with the highest RT-ARD score and 19 patients with the lowest RT-ARD score. They were investigated by multimodal rectal sensory stimulation, standard anal physiological tests. Changes of the rectal mucosa were assessed by flexible sigmoidoscopy and graded by the Vienna Rectoscopy Score (VRS).Results. The mean follow-up time was 3.8 (range, 2.8; 8.6) years in patients with high RT-ARD and 3.8 (range, 2.6; 5.9) in patients with low RT-ARD. Endoscopic evaluation revealed higher VRS scores in patients with high RT-ARD compared to patients with low RT-ARD (p = 0.002). Patients with high RT-ARD had increased rectal sensory response to distension manifested both as volume (p = 0.006) and cross-sectional area (p = 0.04), and they had reduced maximum anal resting pressure assessed by anal manometri (p = 0.02).Conclusions. Long-term anorectal symptoms correlate to changes in anorectal biomechanical properties and rectal mucosal injury. Our data suggests that RT-induced long-term anorectal dysfunction is multifactorial caused by injury of the rectal mucosa and the internal anal sphincter combined with increased rectal sensitivity and reduced rectal functional capacity.
Automatic segmentation of the heart in radiotherapy for breast cancer
Creators: name: Lorenzen, Ebbe L.
name: Ewertz, Marianne
name: Brink, Carsten
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Cancer
subject: Information and Computing Sciences
subject: Biological Sciences
subject: Earth and Environmental Sciences
subject: Physiology
subject: Medicine
subject: Engineering

description: Background. The aim of this study was to evaluate two fully automatic segmentation methods in comparison with manual delineations for their use in delineating the heart on planning computed tomography (CT) used in radiotherapy for breast cancer.Material and methods. Automatic delineation of heart in 15 breast cancer patients was performed by two different automatic delineation systems. Analysis of accuracy and precision of the differences between manual and automatic delineations were evaluated on volume, mean dose, maximum dose and spatial distance differences. Two sets of manual delineations were used in the evaluation: 1) a set prior to common delineation guidelines; and 2) a second set repeated with a common set of guidelines.Results. Systematic differences between automatic and manual delineations were small for volume as well as dose. The uncertainty of the difference in volume was smaller than or similar to the inter-observer variation in manual delineations. For dose, the uncertainty was similar to manual delineations performed without common guidelines but slightly higher than the variation in manual delineations with common guidelines. Spatial differences between average manual and automatic delineations were largest at the base of the heart, where also large variations are observed in the manual delineations. Both algorithms could be improved slightly at the apex of the heart where the variation of automatic delineation was larger than for the manual delineations.Conclusion. Automatic delineation is an equal alternative to manual delineation when compared to the inter-observer variation. The reduction in precision of measured dose was small compared to other uncertainties affecting the estimated heart dose and would for most applications be outweighed by the benefits of fully automated delineations.
"After the Terror Attacks in Hanau: Are German Postmigrants' Demands for Linguistic Changes in the Public Debate finally being Heard?"
Creators: name: Weissenberg, Melanie
Publisher: name: Zenodo
Year: 2020

description: Blog Post titled “After the Terror Attacks in Hanau: Are German Postmigrants’ Demands for Linguistic Changes in the Public Debate finally being Heard?” Istanbul Bilgi University PRIME Youth Website, https://bpy.bilgi.edu.tr/en/blog/after-the-terror-attacks-in-hanau-are-german-postm/