cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
High throughput centrifugal electrospinning of polyacrylonitrile nanofibers for carbon fiber nonwovens
Creators: name: Hoffmann, Andreas
name: Kuehne, Alexander J. C.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: rotational spinning
subject: PAN nanofibers
subject: nonwovens
subject: DDC 530 / Physics
subject: DDC 540 / Chemistry & allied sciences
subject: Electrospinning
subject: Elektrospinnen
subject: Vliesstoff

description: Carbon nanofiber nonwovens are promising materials for electrode or filtration applications; however, their utilization is obviated by a lack of high throughput production methods. In this study, we utilize a highly effective high-throughput method for the fabrication of polyacrylonitrile (PAN) nanofibers as a nonwoven on a dedicated substrate. The method employs rotational-, air pressure- and electrostatic forces to produce fibers from the inner edge of a rotating bell towards a flat collector. We investigate the impact of all above-mentioned forces on the fiber diameter, morphology, and bundling of the carbon-precursor PAN fibers. The interplay of radial forces with collector-facing forces has an influence on the uniformity of fiber deposition. Finally, the obtained PAN nanofibers are converted to carbon nonwovens by thermal treatment.
Thinking Colours
Creators: name: Warburton, David Alan
Publisher: name: University Library Tübingen
Year: 2018

description: Reviewed Book
Bogushevskaya, Victoria and Elisabetta Colla, eds. Thinking Colours: Perception, Translation and Representation. Newcastle: Cambridge Scholars Publishing, 2015. ISBN 978-1-4438-7529-5.

Abstract
The editors state that ‘The place where science meets the humanities is cognitive culture studies ... and this is where our book begins ...’ 1 . The outcome of a gathering of scholars and artists in Lisbon, the book offers very different approaches to colour, each following a theme and offering a bibliography. The contributions range from state-of-the-art disputes about theoretical aspects to the use of colour in modern literature and advertising. The editors have created a sequence classifying the various contributions under headings related to ‘Cognition,’ ‘Language and Translation,’ ‘Literature,’ ‘Art,’ and ‘Space’. This review uses a different system.
description: Colour Turn, Nr. 1 (2018): Kapitel 1
Additional file 1 of Impacts of inflammatory cytokines on depression: a cohort study
Creators: name: Liu, Fei
name: Yang, Yang
name: Fan, Xiao-Wei
name: Zhang, Ning
name: Wang, Shuo
name: Shi, Yi-Jun
name: Hu, Wei-Jiang
name: Wang, Chun-Xue
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health

description: Supplementary Material 1
Extracellular vesicles in musculoskeletal pathologies and regeneration
Creators: name: Herrmann, Marietta
name: Diederichs, Solvig
name: Melnik, Svitlana
name: Riegger, Jana
name: Trivanović, Drenka
name: Li, Shushan
name: Jenei-Lanzl, Zsuzsa
name: Brenner, Rolf E.
name: Huber-Lang, Markus
name: Zaucke, Frank
name: Schildberg, Frank A.
name: Grässel, Susanne
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: MSC
subject: iMP
subject: cell-free therapeutics
subject: DDC 610 / Medicine & health
subject: Extracellular vesicles
subject: Exosomes
subject: Musculoskeletal diseases
subject: Regeneration
subject: Bewegungsapparat
subject: Krankheit
subject: Exosom
subject: Vesikel

description: The incidence of musculoskeletal diseases is steadily increasing with aging of the population. In the past years, extracellular vesicles (EVs) have gained attention in musculoskeletal research. EVs have been associated with various musculoskeletal pathologies as well as suggested as treatment option. EVs play a pivotal role in communication between cells and their environment. Thereby, the EV cargo is highly dependent on their cellular origin. In this review, we summarize putative mechanisms by which EVs can contribute to musculoskeletal tissue homeostasis, regeneration and disease, in particular matrix remodeling and mineralization, pro-angiogenic effects and immunomodulatory activities. Mesenchymal stromal cells (MSCs) present the most frequently used cell source for EV generation for musculoskeletal applications, and herein we discuss how the MSC phenotype can influence the cargo and thus the regenerative potential of EVs. Induced pluripotent stem cell-derived mesenchymal progenitor cells (iMPs) may overcome current limitations of MSCs, and iMP-derived EVs are discussed as an alternative strategy. In the last part of the article, we focus on therapeutic applications of EVs and discuss both practical considerations for EV production and the current state of EV-based therapies.
Additional file 2 of Impacts of inflammatory cytokines on depression: a cohort study
Creators: name: Liu, Fei
name: Yang, Yang
name: Fan, Xiao-Wei
name: Zhang, Ning
name: Wang, Shuo
name: Shi, Yi-Jun
name: Hu, Wei-Jiang
name: Wang, Chun-Xue
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health

description: Supplementary Material 2
sj-docx-1-dhj-10.1177_20552076231179007 - Supplemental material for Untargeted metabolomics characterization of the resectable pancreatic ductal adenocarcinoma
Creators: name: Cao, Ying-Ying
name: Guo, Kai
name: Zhao, Rui
name: Li, Yuan
name: Lv, Xiao-Jing
name: Lu, Zi-Peng
name: Tian, Lei
name: Ren, Shuai
name: Wang, Zhong-Qiu
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Health and Community Services
subject: Cardiology
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Nursing not elsewhere classified
subject: Oncology and Carcinogenesis not elsewhere classified
subject: Aged Health Care
subject: Public Health and Health Services not elsewhere classified
subject: Engineering not elsewhere classified
subject: Anthropology
subject: FOS: Sociology
subject: Cultural Studies not elsewhere classified
subject: Information and Computing Sciences not elsewhere classified
subject: Organisation and Management Theory
subject: Science Policy
subject: Social Policy
subject: Sociology

description: Supplemental material, sj-docx-1-dhj-10.1177_20552076231179007 for Untargeted metabolomics characterization of the resectable pancreatic ductal adenocarcinoma by Ying-Ying Cao, Kai Guo, Rui Zhao, Yuan Li, Xiao-Jing Lv, Zi-Peng Lu, Lei Tian, Shuai Ren and Zhong-Qiu Wang in DIGITAL HEALTH
Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma
Creators: name: Lopez, Cristina
name: Kleinheinz, Kortine
name: Aukema, Sietse M.
name: Rohde, Marius
name: Bernhart, Stephan H.
name: Hübschmann, Daniel
name: Wagener, Rabea
name: Toprak, Umut H.
name: Raimondi, Francesco
name: Kreuz, Markus
name: Waszak, Sebastian M.
name: Huang, Zhiqin
name: Sieverling, Lina
name: Paramasivam, Nagarajan
name: Seufert, Julian
name: Sungalee, Stephanie
name: Russell, Robert B.
name: Bausinger, Julia
name: Kretzmer, Helene
name: Ammerpohl, Ole
name: Bergmann, Anke K.
name: Binder, Hans
name: Borkhardt, Arndt
name: Brors, Benedikt
name: Claviez, Alexander
name: Doose, Gero
name: Feuerbach, Lars
name: Haake, Andrea
name: Hansmann, Martin-Leo
name: Höll, Jessica
name: Hummel, Michael
name: Korbel, Jan O.
name: Lawerenz, Chris
name: Lenze, Dido
name: Radlwimmer, Bernhard
name: Richter, Julia
name: Rosenstiel, Philip
name: Rosenwald, Andreas
name: Schilhabel, Markus B.
name: Stein, Harald
name: Stilgenbauer, Stephan
name: Stadler, Peter F.
name: Szczepanowski, Monika
name: Weniger, Marc A.
name: Zapatka, Marc
name: Eils, Roland
name: Lichter, Peter
name: Löffler, Markus
name: Möller, Peter
name: Trümper, Lorenz
name: Klapper, Wolfram
name: ICGC MMML-Seq Consortium
name: Hoffmann, Steve
name: Küppers, Ralf
name: Burkhardt, Birgit
name: Schlesner, Matthias
name: Siebert, Reiner
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Oncology
subject: DDC 610 / Medicine & health
subject: Burkitt lymphoma
subject: Genes, Neoplasm
subject: Lymphocytes
subject: Lymphoid tissue
subject: Burkitt-Lymphom
subject: Onkogen
subject: Lymphozyt
subject: Lymphatisches Organ

description: Burkitt lymphoma (BL) is the most common B-cell lymphoma in children. Within the International Cancer Genome Consortium (ICGC), we performed whole genome and transcriptome sequencing of 39 sporadic BL. Here, we unravel interaction of structural, mutational, and transcriptional changes, which contribute to MYC oncogene dysregulation together with the pathognomonic IG-MYC translocation. Moreover, by mapping IGH translocation breakpoints, we provide evidence that the precursor of at least a subset of BL is a B-cell poised to express IGHA. We describe the landscape of mutations, structural variants, and mutational processes, and identified a series of driver genes in the pathogenesis of BL, which can be targeted by various mechanisms, including IG-non MYC translocations, germline and somatic mutations, fusion transcripts, and alternative splicing.
Affective language, interpretation bias and its molecular genetic variations: exploring the relationship between genetic variations of the OXTR gene (rs53576 and rs2268498) and the emotional evaluation of words related to the self or the other
Creators: name: Meixner, Friedrich
name: Montag, Christian
name: Herbert, Cornelia
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: OXTR
subject: self
subject: emotional evaluation
subject: rs53576
subject: interpretation bias
subject: DDC 150 / Psychology
subject: Polymorphism, Single nucleotide
subject: Oxytocin
subject: Language
subject: Social cognition
subject: SNP
subject: Soziale Wahrnehmung
subject: Sprache

description: Several studies have demonstrated links between oxytocin and socio-emotional information processing. Regarding the frequently studied single nucleotide polymorphism (SNP) rs53576 and the less studied, functional polymorphism rs2268498 of the oxytocin receptor (OXTR) gene, previous research suggested that their variants might be associated with different proficiency in the processing of social information. Differences between the genotype variants are not restricted to non-verbal stimulus processing but have also been reported in the verbal domain. Moreover, there is evidence that oxytocin expression influences empathic communication and language development during childhood, indicating that language-based theory-of-mind abilities may be affected by interindividual differences in OXTR genotypes as well. The present study therefore investigates whether two prominent SNPs of the OXTR gene (rs53576 GG vs. A+; rs2268498 TT vs. C+) also play a role in the affective evaluation of verbal stimuli varying in emotional valence and in self-other reference. Participants (N = 149 Caucasian participants, 104 females; A+: n = 80, GG: n = 69; C+: n = 98, TT: n = 51) were presented a series of written, self-, other-, and unreferenced words of positive, negative, and neutral valence and asked to affectively evaluate each word pair as positive, negative, or neutral by button press. In line with previous research, reaction times and accuracy (number of valence-congruent responses) showed a self-positivity bias (i.e., preferential processing of self-related positive words), which, however, was unaffected by participants’ genotype. Regarding affective evaluation of neutral words (interpretation bias), A+ carriers displayed a weaker positive interpretation bias compared to GG carriers in the other– and unreferenced stimulus categories. C+ carriers showed a weaker positive interpretation bias than TT carriers in the self-reference condition and in the other-reference condition. These effects were independent from participants’ gender. The present results suggest that the OXTR genotype and hence participants’ genetic oxytocin sensitivity may cause an interpretation bias in the spontaneous appraisal of neutral words.
sj-docx-1-jom-10.1177_01492063221126707 - Supplemental material for How Shareholders Impact Stakeholder Interests: A Review and Map for Future Research
Creators: name: DesJardine, Mark R.
name: Zhang, Muhan
name: Shi, Wei
Publisher: name: SAGE Journals
Year: 2022
Subjects: Organisation and Management Theory

description: Supplemental material, sj-docx-1-jom-10.1177_01492063221126707 for How Shareholders Impact Stakeholder Interests: A Review and Map for Future Research by Mark R. DesJardine, Muhan Zhang, and Wei Shi in Journal of Management
„Future Shopping“: eine Technologievorausschau anhand IT-gestützter bibliometrischer Analyse und Szenariotechnik
Creators: name: Gentner, Daniel
name: Stern, Marc
name: Stelzer, Birgit
name: Schiebel, Edgar
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: E-Commerce
subject: Technology foresight
subject: DDC 330 / Economics
subject: Business forecasting
subject: Shopping
subject: Future markets
subject: Bibliometrics
subject: Electronic commerce
subject: Bibliometrie
subject: Electronic Commerce
subject: Szenario

description: Neue technische Möglichkeiten eröffnen das Potenzial, das Einkaufsverhalten und das „Shopping-Erlebnis“ der Konsumenten in Zukunft radikal zu verändern. Der Forschungsbericht ergründet durch eine systematische Zukunftsvorausschau die kurz- und langfristige Entwicklung des Einzelhandels. Es werden zwei Vorausschaumethoden in Kombination angewandt. Mittels einer bibliometrischen Analyse beschreiben die Autoren die Forschungslandschaft zum Themenbereich „Future Shopping“, indem zentrale Wissenschaftler, wichtige Konferenzen und führende Organisationen hinsichtlich Publikationsintensität identifiziert werden. Außerdem werden über Netzwerkanalysen wesentliche Autorenkooperationen, Forschungsdisziplinen sowie aktuell bedeutsame Forschungsfelder aufgezeigt. Die Erkenntnisse aus der bibliometrischen Analyse nutzen die Autoren schließlich zur Bildung dreier möglicher, ganzheitlicher Zukunftsbilder innerhalb der Szenariotechnik. Zukünftige Entwicklungen im Einzelhandel werden systematisch entwickelt und detailliert beschrieben. Außerdem leiten die Autoren aus den aktuellen Forschungsfeldern emergente Technologien ab und bewerten deren Auswirkung bzw. zukünftiges Potential innerhalb der drei Szenarien. Die Autoren zeigen in diesem Bericht abschließend anhand eines Fallbeispiels auf, welche Chancen der Einzelhandel aus neuen Technologien ziehen kann und welchen Einfluss dies auf die Gestaltung zukünftiger Geschäftsmodelle haben wird.
The health-related quality of life of sarcoma patients and survivors in germany—cross-sectional results of a nationwide observational study (PROSa)
Creators: name: Eichler, Martin
name: Hentschel, Leopold
name: Richter, Stephan
name: Hohenberger, Peter
name: Kasper, Bernd
name: Andreou, Dimosthenis
name: Pink, Daniel
name: Jakob, Jens
name: Singer, Susanne
name: Grützmann, Robert
name: Fung, Stephen
name: Wardelmann, Eva
name: Arndt, Karin
name: Heidt, Vitali
name: Hofbauer, Christine
name: Fried, Marius
name: Gaidzik, Verena I.
name: Verpoort, Karl
name: Ahrens, Marit
name: Weitz, Jürgen
name: Schaser, Klaus-Dieter
name: Bornhäuser, Martin
name: Schmitt, Jochen
name: Schuler, Markus K.
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: health-related quality of life
subject: observational study
subject: clinically important restrictions and symptoms
subject: DDC 610 / Medicine & health
subject: Sarcoma
subject: Rare diseases
subject: Quality of life
subject: Sarkom
subject: Seltene Krankheit
subject: Lebensqualität

description: Sarcomas are rare cancers with high heterogeneity in terms of type, location, and treatment. The health-related quality of life (HRQoL) of sarcoma patients has rarely been investigated and is the subject of this analysis. Adult sarcoma patients and survivors were assessed between September 2017 and February 2019 in 39 study centers in Germany using standardized, validated questionnaires (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30)). Associated factors were analyzed exploratively using multivariable linear regressions. Among 1113 patients, clinically important limitations and symptoms were most pronounced in emotional (63%, 95% CI 60–66%), physical (60%, 95% CI 57–62%), role functioning (51%, 95% CI 48–54%), and pain (56%, 95% CI 53–59%) and fatigue (51%, 95% CI 48–54%). HRQoL differed between tumor locations with lower extremities performing the worst and sarcoma types with bone sarcoma types being most affected. Additionally, female gender, higher age, lower socioeconomic status, recurrent disease, not being in retirement, comorbidities, and being in treatment were associated with lower HRQoL. Sarcoma patients are severely restricted in their HRQoL, especially in functioning scales. The heterogeneity of sarcomas with regard to type and location is reflected in HRQoL outcomes. During treatment and follow-up, close attention has to be paid to the reintegration of the patients into daily life as well as to their physical abilities and emotional distress.
Additional file 2 of Integrated analysis of transcriptome and genome variations in pediatric T cell acute lymphoblastic leukemia: data from north Indian tertiary care center
Creators: name: Singh, Minu
name: Sharma, Pankaj
name: Bhatia, Prateek
name: Trehan, Amita
name: Thakur, Rozy
name: Sreedharanunni, Sreejesh
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 2- T-ALL WES and outcome data
Data from: Different evolutionary pathways lead to incomplete convergence of elongate body shapes in carnivoran mammals
Creators: name: Law, Chris
Publisher: name: Zenodo
Year: 2022

description: Although convergence is often recognized as a ubiquitous feature across the Tree of Life, whether the underlying traits also exhibit similar evolutionary pathways towards convergent forms puzzles biologists. In carnivoran mammals, "elongate," "slender," and "long" are often used to describe and even to categorize mustelids (martens, polecats, and weasels), herpestids (mongooses), viverrids (civets and genets), and other carnivorans together. But just how similar these carnivorans are and whether there is convergence in the morphological component that contribute to elongation has never been assessed. Here, I found that these qualitatively-described elongate carnivorans exhibited incomplete convergence towards elongate bodies compared to other terrestrial carnivorans. In contrast, the morphological components underlying body shape variation do not exhibit convergence despite evidence that these components are more elongate in elongate carnivorans compared to non-elongate carnivorans. Furthermore, these components also exhibited shorter but different phylogenetic half-lives towards more elongate adaptive peaks, indicating that different selective pressures can create multiple pathways to elongation. Incorporating the fossil record will facilitate further investigation of whether body elongation evolved adaptively or if it is simply a retained ancestral trait.
description: Supplementary Methods Tables S1-S9
sj-docx-1-npx-10.1177_1934578X221131408 - Supplemental material for Preparation of 4,4-Dimethyloxazoline and Pyrrolidine Derivatives from Fatty Acid Methyl Esters Using Sodium Borohydride: Mild and Simple One-Pot Derivatization Procedures for a Gas Chromatographic–Mass Spectrometric Analysis of Fatty Acids
Creators: name: Santalova, Elena A.
name: Svetashev, Vasily I.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-npx-10.1177_1934578X221131408 for Preparation of 4,4-Dimethyloxazoline and Pyrrolidine Derivatives from Fatty Acid Methyl Esters Using Sodium Borohydride: Mild and Simple One-Pot Derivatization Procedures for a Gas Chromatographic–Mass Spectrometric Analysis of Fatty Acids by Elena A. Santalova and Vasily I. Svetashev in Natural Product Communications
Stadtbild - Stadtraum
Creators: name: Nagler, Heinz
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 300 / Social sciences
subject: Cities and towns; Planning
subject: Öffentlicher Raum
subject: Online-Publikation
subject: Ringvorlesung
subject: Stadtbild
subject: Städtebau
subject: Stadtentwicklung

description: Städtebau heißt gestalten im großen Maßstab. Zum Verstehen von Prozessen und Programmen muss immer die Fähigkeit zum Gestalten hinzutreten. Städte zu gestalten heißt Räume schaffen - genauer Zwischenräume. Von besonderem Interesse für den Entwerfer ist hierbei die Ambivalenz zwischen der Auffassung vom fließenden Raum und dem Raum als formal definiertem Behälter. Anhand aktueller städtischer Beispiele soll die schwierige Suche nach dem zeitgemäßen öffentlichen Raum illustriert werden.
Supplemental Material - Additive manufacturing of silicone-thermoplastic elastomeric composite architectures
Creators: name: Liu, Wenbo
name: Campbell, Ronald R
name: Periyasamy, Mookkan
name: Hickner, Michael A
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental Material for Additive manufacturing of silicone-thermoplastic elastomeric composite architectures by Wenbo Liu, Ronald R Campbell, Mookkan Periyasamy and Michael A Hickner in Journal of Composite Materials
sj-docx-2-mdm-10.1177_0272989X231173699 – Supplemental material for Bayesian Models with Spatial Correlation Improve the Precision of EQ-5D-5L Value Sets
Creators: name: Che, Menglu
name: Xie, Feng
name: Thomas, Stephanie
name: Pullenayegum, Eleanor
Publisher: name: SAGE Journals
Year: 2023
Subjects: Health and Community Services
Public Health and Health Services not elsewhere classified
Sociological Methodology and Research Methods

description: Supplemental material, sj-docx-2-mdm-10.1177_0272989X231173699 for Bayesian Models with Spatial Correlation Improve the Precision of EQ-5D-5L Value Sets by Menglu Che, Feng Xie, Stephanie Thomas and Eleanor Pullenayegum in Medical Decision Making
Häufigkeiten von Übergriffen auf Kinder und Jugendliche durch Angehörige der Heil- und Pflegeberufe
Creators: name: Rassenhofer, Miriam
name: Korger, Simone
name: Fegert, Jörg M.
name: Hoffmann, Ulrike
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Kindesmisshandlung
subject: institutioneller Kindesmissbrauch
subject: medizinisch-therapeutisches Personal
subject: child maltreatment
subject: institutional child abuse
subject: health professionals
subject: medical-therapeutic institutions
subject: DDC 150 / Psychology
subject: Child sexual abuse
subject: Professional employees; Sexual behavior
subject: Child abuse, Sexual
subject: Child, Hospitalized
subject: Child, Institutionalized
subject: Professional misconduct
subject: Kindesmisshandlung
subject: Kind
subject: Sexueller Missbrauch
subject: Medizinische Einrichtung

description: Zusammenfassung. Theoretischer Hintergrund: Kindesmisshandlung, -missbrauch und Vernachlässigung stellen ein gesamtgesellschaftliches Entwicklungsrisiko für Kinder in Deutschland dar. Zweithäufigster Kontext des Geschehens nach dem familiären Umfeld sind Institutionen. Fragestellung: Der vorliegende Artikel gibt eine Übersicht zu Häufigkeiten von Übergriffen durch Angehörige der Heil- und Pflegeberufe mit Schwerpunkt auf dem kinder- und jugendpsychiatrischen/-psychotherapeutischen Bereich. Methode: Mittels Literaturrecherche wird der Forschungsstand zum Thema dargestellt. Ergebnisse: Neben Auswertungen zu Zwangsmaßnahmen, welche von Betroffenen häufig als viktimisierend erlebt werden, existieren für Deutschland zwei repräsentative retrospektive Befragungen zum medizinischen Bereich. Hier ergaben sich Prävalenzen zwischen einem Fünftel und einem Drittel der Befragten, die mindestens eine Form von Gewalt oder Vernachlässigung bejahten. Diskussion und Schlussfolgerung: Neben alarmierenden Zahlen zeigt sich der große Bedarf an weiterer Forschung zum Thema.
Additional file 1 of Integrated mRNA- and miRNA-sequencing analyses unveil the underlying mechanism of tobacco pollutant-induced developmental toxicity in zebrafish embryos
Creators: name: Chen, Jiasheng
name: Lin, Yuxin
name: Gen, Deyi
name: Chen, Wanxian
name: Han, Rui
name: Li, Hao
name: Tang, Shijie
name: Zheng, Shukai
name: Zhong, Xiaoping
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. The primer sequences used for gene expression studies were shown in Table S1.
Cathelicidin contributes to the restriction of Leishmania in human host macrophages
Creators: name: Crauwels, Peter
name: Bank, Elena
name: Walber, Bianca
name: Wenzel, Ulf Alexander
name: Agerberth, Birgitta
name: Chanyalew, Menberework
name: Abebe, Markos
name: König, Renate
name: Ritter, Uwe
name: Reiling, Norbert
name: Van Zandbergen, Ger
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: cathelicidin (LL-37)
subject: human primary immune cells
subject: antimicrobial activity
subject: VITAMIN-D-RECEPTOR
subject: IMMUNE-RESPONSE
subject: CAMP GENE
subject: LL-37
subject: INFECTION
subject: SKIN
subject: INDUCTION
subject: DDC 610 / Medicine & health
subject: Leishmaniasis; Immunology
subject: Macrophages
subject: Vitamin D
subject: Pore forming cytotoxic proteins
subject: Receptors, Calcitriol
subject: Antimicrobial cationic peptides
subject: Leishmania
subject: Makrophage
subject: Antimikrobieller Wirkstoff

description: In cutaneous Leishmaniasis the parasitic control in human host macrophages is still poorly understood. We found an increased expression of the human cathelicidin CAMP in skin lesions of Ethiopian patients with cutaneous leishmaniasis. Vitamin D driven, Cathelicidin-type antimicrobial peptides (CAMP) play an important role in the elimination of invading microorganisms. Recombinant cathelicidin was able to induce cell-death characteristics in Leishmania in a dose dependent manner. Using human primary macrophages, we demonstrated pro-inflammatory macrophages (hMDM1) to express a higher level of human cathelicidin, both on gene and protein level, compared to anti-inflammatory macrophages (hMDM2). Activating the CAMP pathway using Vitamin D in hMDM1 resulted in a cathelicidin-mediated-Leishmania restriction. Finally, a reduction of cathelicidin in hMDM1, using a RNA interference (RNAi) approach, increased Leishmania parasite survival. In all, these data show the human cathelicidin to contribute to the innate immune response against Leishmaniasis in a human primary cell model.
Supplemental Material - Outcomes associated with prolonged ECMO in COVID-19 associated ARDS: A single center experience
Creators: name: Shah, Purav
name: Miller, Casey
name: Parilla, Gustavo
name: Daneshmand, Mani
name: Creel-Bulos, Christina
Publisher: name: SAGE Journals
Year: 2023
Subjects: Cardiology
Surgery

description: Supplemental Material for Outcomes associated with prolonged ECMO in COVID-19 associated ARDS: A single center experience by Purav Shah, Casey Miller, Gustavo Parilla, Mani Daneshmand and Christina Creel-Bulos in Ergonomics in Design: The Quarterly of Human Factors Applications
Psychological care in children and adolescents with type 1 diabetesin a real-world setting and associations with metabolic control
Creators: name: Galler, Angela
name: Hilgard, Dörte
name: Bollow, Esther
name: Hermann, Thomas
name: Kretschmer, Nicole
name: Maier, Berthold
name: Mönkemöller, Kirsten
name: Schiel, Ralf
name: Holl, Reinhard
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Clinical
subject: HbA1c
subject: Psychology
subject: FOS: Psychology
subject: DDC 150 / Psychology
subject: DDC 610 / Medicine & health
subject: Adolescent
subject: Child
subject: Diabetes mellitus, Type 1
subject: Glycated hemoglobin A
subject: Jugend
subject: Kind
subject: Diabetes mellitus Typ 1
subject: Psychologische Betreuung

description: Background: International guidelines recommend psychosocial care for children and adolescents with type 1 diabetes. Objective: To assess psychological care in children and adolescents with type 1 diabetes in a real‐world setting and to evaluate associations with metabolic outcome. Methods: Delivery of psychological care, HbA1c, and rates of severe hypoglycemia and diabetic ketoacidosis (DKA) in children and adolescents with type 1 diabetes from 199 diabetes care centers participating in the German diabetes survey (DPV) were analyzed. Results: Overall, 12 326 out of 31 861 children with type 1 diabetes were supported by short‐term or continued psychological care (CPC). Children with psychological care had higher HbA1c (8.0% vs 7.7%, P <.001) and higher rates of DKA (0.032 vs 0.021 per patient‐year, P <.001) compared with children without psychological care. In age‐, sex‐, diabetes duration‐, and migratory background‐matched children, HbA1c stayed stable in children supported by CPC during follow‐up (HbA1c 8.5% one year before psychological care started vs 8.4% after two years, P = 1.0), whereas HbA1c was lower but increased significantly by 0.3% in children without psychological care (HbA1c 7.5% vs 7.8% after two years, P <.001). Additional HbA1c‐matching showed that the change in HbA1c during follow‐up was not different between the groups, but the percentage of children with severe hypoglycemia decreased from 16.3% to 10.7% in children receiving CPC compared with children without psychological care (5.5% to 5.8%, P =.009). Conclusions: In this real‐world setting, psychological care was provided to children with higher HbA1c levels. CPC was associated with stable glycemic control and less frequent severe hypoglycemia during follow‐up.
title: DataCite Use Cases Around the World: Universidad Nacional de Rosario, Argentina
Creators: name: Bongiovani, Paola Carolina
name: Garduño-Magaña, Arturo
Publisher: name: DataCite
publisherIdentifier: https://ror.org/04wxnsj81
publisherIdentifierScheme: ROR
Year: 2024

description: DataCite use cases around the world: Welcome to our blog series shining a spotlight on how research institutions integrate DataCite infrastructure into their systems and workflows. Join us as we explore real-world examples, best practices, and the impact of the DataCite community.

Paola Bongiovani is the Coordinator of the Open Access Management Unit at the National University of Rosario (UNR), Argentina, overseeing the UNR Academic Data Repository (RDA-UNR), the UNR Hypermedia Repository, and the UNR Journals portal. With over 17 years of management experience at her institution and nationally, Paola researches, teaches, and promotes open science in Argentina and the region. In recent years, she has focused on the management and curation of research data.
La Prescription en Droit Canonique et dans la Tradition du Code de Napoléon avec Applications Particulières aux Délits les Plus Graves Touchant aux Moeurs
Creators: name: Nkouaya Mbandji, Valere
Publisher: name: Université Saint-Paul / Saint Paul University
Year: 2018
Subjects: Prescription
harmonisation
crimes
droit pénal canonique
droits des enfants
abus sexuels
Statutes of limitation
mineurs
peine canonique
tradition du droit civil
droit comparé
délits canoniques
crimes contre l'humanité
imprescriptibilité
renvoi formel
renvoi matériel
droit pénal international
justice

description: La présente thèse traite de la prescription en droit canonique et dans la tradition du Code Napoléon. Elle fait des applications particulières aux délits sexuels qualifiés de « délits les plus graves » perpétrés par des clercs et des religieux sur des personnes mineures. La thèse pose le problème actuel de l’opportunité de la prescription canonique pour lesdits délits. La thèse soulève aussi le problème de l'harmonisation de la législation canonique avec celle des États en matière de lutte contre les abus sexuels sur des personnes mineures et des personnes vulnérables.
title: Casos de uso de DataCite por el mundo: Universidad Nacional de Rosario, Argentina
Creators: name: Bongiovani, Paola Carolina
name: Garduño-Magaña, Arturo
Publisher: name: DataCite
publisherIdentifier: https://ror.org/04wxnsj81
publisherIdentifierScheme: ROR
Year: 2024

description: Casos de uso de DataCite en todo el mundo: Bienvenidos a nuestra serie de blogs que destacan cómo las instituciones de investigación integran la infraestructura de DataCite en sus sistemas y flujos de trabajo. Únanse a nosotros mientras exploramos ejemplos del mundo real, mejores prácticas y el impacto de la comunidad de DataCite.

Paola Bongiovani es Coordinadora de la Unidad de Gestión de Acceso Abierto en la Universidad Nacional de Rosario, Argentina a cargo de los a cargo del Repositorio de Datos Académicos UNR (RDA-UNR), el Repositorio Hipermedial UNR y el portal Revistas UNR. Basada en una sólida experiencia de más de 17 años de gestión en su institución y a nivel nacional, Paola investiga, enseña y promociona la ciencia abierta en Argentina y la región. En estos últimos años se focaliza en la gestión y curación de datos de investigación.
To Lessen Repression and Depression: The Relationship Between Sexual Repression and Mental Health Among Lesbian, Gay, Bisexual, Transgender, and Queer Individuals
Creators: name: Jacobson, Ariele
Publisher: name: Université Saint-Paul / Saint Paul University
Year: 2018
Subjects: sexual
repression
sexuality
LGBTQ+

description: While many researchers have studied the specific struggles of members of the gay, lesbian, bisexual, transgender, queer (LGBTQ+) community, sexual repression has not been mentioned in the literature. This paper summarizes the results of a qualitative research with ten participants, who identified as members of the LGBTQ+ community, and who shared their experiences surrounding sexual repression. It analyzes sexual repression as defined by Sigmund Freud and applies it to the struggles of LGBTQ+ individuals in Ottawa, Ontario. More specifically, this paper examines the factors that participants believe lead to and maintain sexual repression and how they perceive that this impacts the mental health of the people who suffer from it. The main themes that arose during this research were as follows: misconceptions held by others, including expectations, rules, and objectifications; stigma; belonging, acceptance, and sense of community; internalized view of self and emotional / mental impact; safety, including implications of disclosure and safe spaces; and attitudes about sex and the self as a sexual / gendered being. The participants explained how they perceive that these factors have led to and maintained sexual repression at different points in their lives and how they believe that they have influenced their mental health.
The Spouse as Divine Encounter: Renewing the Spiritual Understanding of Marriage in Roman Catholic Theology
Creators: name: Bowen, Kathryn Anne Meghan
Publisher: name: Université Saint-Paul / Saint Paul University
Year: 2018
Subjects: marriage
Roman Catholic
spousal spirituality
sanctification

description: In the recent Amoris Laetitia, Pope Francis states that the Church must reflect further on God’s action within the marriage rite. (art. 75) Perhaps what is required, instead, is further reflection on the presence of God within the marriage relationship. Although it has been the subject of theological reflection throughout most of Church history, there is a lack of sacramental understanding of marriage within Roman Catholic theology. Theological reflection on marriage through the 20th-century has tended to focus on the ethical and social questions surrounding family life while neglecting the sacramentality of the spouses’ relationship. Without negating the insights gained through such reflection, this paper presents a means of expanding marriage theology by employing a sacramental lens. The current paper opens with a survey of modern magisterial documents (dating from 1880 to the present), exploring the ways in which the nature of marriage is presented in each. Following that, further documents will be examined as examples of marriage theology being appropriated as a basis for moral theology, thus reinforcing the link between marriage and questions of sexual ethics. Writings of early 20th-century Russian Orthodox writers will be presented as a more sacramental model of marriage theology. Finally, foundational texts from the marriage spirituality movement in the Roman Catholic Church will serve as examples of how a sacramental understanding of the spouses’ relationship may be drawn out from traditional Catholic marriage theology.
Bayesian Phase II optimization for time-to-event data based on historical information
Creators: name: Bertsche, Anja
name: Fleischer, Frank
name: Beyersmann, Jan
name: Nehmiz, Gerhard
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: Proof-of-concept
subject: Go–NoGo decision
subject: Bayes
subject: time-to-event
subject: operating characteristics
subject: meta-analytic-predictive prior distribution
subject: DDC 500 / Natural sciences & mathematics
subject: DDC 510 / Mathematics
subject: DDC 610 / Medicine & health
subject: Proof theory
subject: Bayesian statistical decision theory
subject: Bayes-Verfahren
subject: Beweistheorie

description: After exploratory drug development, companies face the decision whether to initiate confirmatory trials based on limited efficacy information. This proof-of-concept decision is typically performed after a Phase II trial studying a novel treatment versus either placebo or an active comparator. The article aims to optimize the design of such a proof-of-concept trial with respect to decision making. We incorporate historical information and develop pre-specified decision criteria accounting for the uncertainty of the observed treatment effect. We optimize these criteria based on sensitivity and specificity, given the historical information. Specifically, time-to-event data are considered in a randomized 2-arm trial with additional prior information on the control treatment. The proof-of-concept criterion uses treatment effect size, rather than significance. Criteria are defined on the posterior distribution of the hazard ratio given the Phase II data and the historical control information. Event times are exponentially modeled within groups, allowing for group-specific conjugate prior-to-posterior calculation. While a non-informative prior is placed on the investigational treatment, the control prior is constructed via the meta-analytic-predictive approach. The design parameters including sample size and allocation ratio are then optimized, maximizing the probability of taking the right decision. The approach is illustrated with an example in lung cancer.
sj-docx-1-jfn-10.1177_10748407231213862 – Supplemental material for Grandparents’ Experiences of Childhood Cancer: A Qualitative Study
Creators: name: Davies, Jenny
name: O’Connor, Moira
name: Halkett, Georgia K. B.
name: Kelada, Lauren
name: Gottardo, Nicholas G.
Publisher: name: SAGE Journals
Year: 2023
Subjects: Nursing not elsewhere classified
Family and Household Studies

description: Supplemental material, sj-docx-1-jfn-10.1177_10748407231213862 for Grandparents’ Experiences of Childhood Cancer: A Qualitative Study by Jenny Davies, Moira O’Connor, Georgia K. B. Halkett, Lauren Kelada and Nicholas G. Gottardo in Journal of Family Nursing
title: Von der Fürsorge zur Sozialhilfe
Creators: name: Wagner, Philipp
Year: 2009

description: In der vorliegenden Diplomarbeit wird die Entwicklung des „zweiten sozialen Netzes“ im Burgenland von 1945 bis 1975 beschrieben. Der Wandel verdeutlicht sich auch in der Be-grifflichkeit – von der „Fürsorge“ zur „Sozialhilfe“. Dargestellt werden die Veränderungen in den rechtlichen Bestimmungen sowie in den dahinter liegenden Intentionen des Gesetzgebers. Außerdem ist die historische Entwicklung der wichtigsten Leitlinien in der österreichischen Sozialgesetzgebung für die Zeit vor dem Untersuchungszeitraum beigefügt. Zugleich gibt es einen Überblick über die verschiedenen Unterstützungsbereiche im Laufe der Jahrzehnte. Parallel dazu werden auch die Veränderungen im „ersten sozialen Netz“ während des gewählten Zeitraumes aufgelistet, um die Interaktion zwischen den beiden sozialen Sicherungssystemen zu dokumentieren. Ebenso findet sich eine Darstellung des Parteienwettbewerbes auf Landesebene im Bereich des Fürsorgewesens. Die Skizzierung der wirtschaftlichen Entwicklung des Burgenlandes nach Ende des Zweiten Weltkrieges rundet die Gesamtdarstellung ab. Dazu kommt eine detaillierte Beschreibung des Landessozialhilfegesetzes von 1974, dass den Schlusspunkt der Untersuchungsperiode darstellt. Im Rahmen eines Exkurses wird auf die Situation der Burgenland-Roma eingegangen, die in diesem Zeitraum nur sehr unzureichend vom sozialen Aufstieg profitieren konnten. Im Mittelpunkt stehen die Auswirkungen der sozialen Unterstützungsmaßnahmen auf die Angehörigen der Volksgruppe. Im abschließenden Resümee werden neben den Ergebnissen der Untersuchung auch überblicksmäßig die nachfolgenden gesetzlichen Veränderungen im Rahmen des Landessozialhilfegesetzes bis zur Fertigstellung dieser Diplomarbeit aufgelistet.
sj-docx-2-heb-10.1177_10901981231217978 – Supplemental material for Prevalence and Correlates of Cervical Cancer Prevention Knowledge Among High School Students in Ghana
Creators: name: Ampofo, Ama Gyamfua
name: Mackenzie, Lisa J
name: Osei Asibey, Shadrack
name: Oldmeadow, Christopher
name: Boyes, Allison W
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Health and Community Services
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Public Health and Health Services not elsewhere classified
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-2-heb-10.1177_10901981231217978 for Prevalence and Correlates of Cervical Cancer Prevention Knowledge Among High School Students in Ghana by Ama Gyamfua Ampofo, Lisa J Mackenzie, Shadrack Osei Asibey, Christopher Oldmeadow and Allison W Boyes in Health Education & Behavior
Mechanisms of change in Internet- and mobile-based interventions for PTSD: a systematic review and meta-analysis
Creators: name: Steubl, Lena
name: Sachser, Cedric
name: Baumeister, Harald
name: Domhart, Matthias
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: digital health
subject: trauma
subject: efficacy
subject: mediators
subject: component studies
subject: DDC 150 / Psychology
subject: DDC 610 / Medicine & health
subject: Telemedicine
subject: Mobile applications
subject: Stress disorders, Post-traumatic
subject: Telemedizin
subject: Posttraumatisches Stresssyndrom

description: Background: While Internet- and mobile-based interventions (IMIs) are potential options to increase the access to evidence-based therapies for post-traumatic stress disorder (PTSD), comprehensive knowledge on their working mechanisms is still scarce. Objective: We aimed to evaluate studies investigating the efficacy and mechanisms of change in IMIs for adults with PTSD. Method: In this systematic review and meta-analysis (PROSPERO CRD42019130314), five databases were consulted to identify relevant studies, complemented by forward (i.e. citation search) and backward (i.e. review of reference lists from included studies) searches. Randomized controlled trials (RCTs) investigating the efficacy of IMIs compared to active controls, as well as component and mediation studies were included. Two independent reviewers extracted the data and assessed the risk of bias and requirements for process research. Random-effects meta-analyses on PTSD symptom severity as primary outcome were conducted and further information was synthesized qualitatively. Results: In total, 33 RCTs were included (N = 5421). The meta-analysis comparing IMIs to non-bonafide active controls yielded a significant standardized mean difference (SMD) of −0.36 (95%CI −0.53 to −0.19) favouring IMIs. Although meta-analytic pooling was not possible for the component and mediation studies, evidence suggests no differential effects regarding PTSD symptom reduction between different levels of support and personalization and between different types of exposure. Moreover, mediation studies revealed significant intervening variable effects for self-efficacy beliefs, perceived physical impairment, social acknowledgement, and trauma disclosure. Conclusions: Results indicate that IMIs for PTSD are superior to active controls. Furthermore, findings may contribute to the development of new interventions by outlining important directions for future research (e.g. regarding requirements for process research) and highlighting potential mechanisms of change (i.e. self-efficacy, perceived physical impairment, social acknowledgement, and trauma disclosure).
Emotion and its relation to cognition from Vygotsky’s perspective
Creators: name: Cong-Lem, Ngo
Publisher: name: Monash University
Year: 2022
Subjects: Educational psychology
Social psychology
Social and personality psychology not elsewhere classified
Cultural theory

description: Vygotsky’s sociocultural theory (VST) has been increasingly utilised as an effective framework to account for the role of emotions in learning and development. Yet, within VST, emotion has neither been systemically theorised nor investigated. This paper contributes to the literature by offering a theoretical discussion of Vygotsky’s perspective on emotion and its relation to cognition. Employing a content analysis approach, three of Vygotsky’s key texts on emotions were closely read and analysed with emerging themes grouped into a system of interrelated theoretical tenets. The insights gained from this paper benefit scholars who are interested in understanding and researching emotions from a VST perspective as well as provide important implications for educational practices.
sj-docx-1-jic-10.1177_08850666231201786 - Supplemental material for Prehospitalization Trauma and Physiologic Factors Associated with the Presence of Post-traumatic Stress 3 Months After PICU Discharge
Creators: name: Chau, Ariya N.
name: Eckberg, Ryan A.
name: Laksana, Eugene
name: Ehrlich, Lili
name: Ledbetter, David R.
name: Aczon, Melissa D.
name: Gold, Jeffrey I.
name: Wetzel, Randall C.
name: Nelson, Lara P.
Publisher: name: SAGE Journals
Year: 2023
Subjects: Emergency Medicine
Aged Health Care
Respiratory Diseases

description: Supplemental material, sj-docx-1-jic-10.1177_08850666231201786 for Prehospitalization Trauma and Physiologic Factors Associated with the Presence of Post-traumatic Stress 3 Months After PICU Discharge by Ariya N. Chau, MD, Ryan A. Eckberg, MS, Eugene Laksana, B.Sc., Lili Ehrlich, PhD, David R. Ledbetter, B.Sc., Melissa D. Aczon, PhD, Jeffrey I. Gold, PhD, Randall C. Wetzel, MBBS, MRCP, LRCS, MSB, FAAP, FCCM, and Lara P. Nelson, MD in Journal of Intensive Care Medicine
Влияние температурных воздействий на оконные профили из поливинилхлорида
Creators: name: Вишторский, Евгений
Publisher: name: ООО Цифра
Year: 2024
Subjects: window
profile
climate
deformation
infiltration
окно
профиль
климат
деформация
инфильтрация

description: Современное строительство и архитектура, Выпуск 6 (49) 2024
Ein fallbasiertes System für die Interpretation von Literatur zur Knochenheilung - SILK
Creators: name: Damm, Daniela
name: Seitz, Alexander
name: Henke, Friedrich Wilhelm Von
name: Uhrmacher, Adelinde
name: Claes, Lutz
name: Wolf, Stephan
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: SILK
subject: DDC 004 / Data processing & computer science
subject: Bone regeneration
subject: Expert systems (Computer science)
subject: Scientific literature; Evaluation
subject: Knochenregeneration

description: Im Projekt SILK wurden fallbasierte Methoden konzipiert und implementiert, die es dem Wissenschaftler erlauben, den Stand der experimentellen Forschung systematisch zu analysieren, neue Ergebnisse im Kontext anderer einzuordnen und ausgewählte Fragestellungen der Wissenschaftler auf dieser Basis effizient zu beantworten. Als exemplarischer Anwendungsbereich diente das Gebiet der Knochenheilung.