cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Evaluation 2 projet HASPUME Histoire et anthropologie du Service public en Méditerranée 2015
Creators: name: LabexMed
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2019

description: Évaluation du projet HASPUME Histoire et anthropologie du Service public en Méditerranée, réalisée en 2015, dans le cadre du programme APRIMED, initié par le LabexMed.
Preparation of an Ionic Liquid-Functionalized Polymer Monolith and Its Application in the Separation of Chinese Herb with HPLC
Creators: name: Junxiao Qin
name: Chunliu Yang
name: Yingying An
name: Erpin Liu
name: Ligai Bai
name: Haiyan Liu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Plant Biology

description: A porous functionalized monolithic material based on ionic liquids (ILs) was produced via in situ polymerization within the confines of a stainless-steel column (50 × 4.6 mm i.d.). In the processes, 1-vinyl-3-butylimidazolium chlorine ionic liquid, 1-dodecylene, and butyl methacrylate were used as ternary monomers; ethylene dimethacrylate as the crosslinker; azobisisobutyronitrile as the initiator; and dodecanol as the porogen. The optimized monolith showed high permeability as 13.54 × 10−14 m2, and high porosity as 75.08%. Then its chromatographic characteristic was estimated by being used as the stationary phase of high performance liquid chromatography (HPLC) to separate the mixtures of aromatic series compounds. Finally, the monolith was used to separate gastrodin from Chinese herb gastrodia rhizome, and benzene, biphenyl from the effluent water, respectively. The column efficiency of the obtained IL-based monolith was calculated by the gastrodin peak as 22,000 plates m−1. Moreover, the repeatability of the method was studied with the RSDs calculated by retention times and peak areas of gastrodin peak as 0.79%, 1.23% (run-to-run, n = 6) and 0.86%, 1.89% (column-to-column, n = 6), respectively. The results confirmed that the produced monolith was successfully used as the stationary phase of HPLC to separate small molecules in real samples with high performance.
Mercury Equation of Anomaly Decrements - al.-Battani by van Dalen (Benno) and Pedersen (Fritz S.) (2008) | Type-B (ID n° 836)
Creators: name: van Dalen (Benno) and Pedersen, Fritz S.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Astronomy
History of astronomy
DISHAS
Astronomical table

description: This is a type B edition: A type-B edition corresponds to a critical edition of several table witnesses:
 it is based on several different editions, themselves based on tables from different primary sources.
 A type-B edition can be based on type-A, type-B or type-C editions.
You can find it on the DISHAS project website from this link: https://dishas.obspm.fr/table-edition/836
Additional file 1 of Role of circulating free DNA in evaluating clinical tumor burden and predicting survival in Chinese metastatic colorectal cancer patients
Creators: name: Xu, Xiaojing
name: Yu, Yiyi
name: Shen, Minna
name: Liu, Mengling
name: Wu, Shengchao
name: Liang, Li
name: Huang, Fei
name: Zhang, Chenlu
name: Guo, Wei
name: Liu, Tianshu
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 1: Supplemental Table 1. The testing panel covering a total of 197 hotspots in plasma. Supplemental Table 2. The testing panel covering a total of 17 hotspots in tissue. Supplemental Table 3. Mutational status in plasma and metastatic sites. Supplemental Table 4. Mutational status and metastatic sites of all the 126 patients.
Dynamic regulation of histone H3K9 is linked to the switch between replication and transcription at the Dbf4 origin-promoter locus
Creators: name: Kylie, Kathleen
name: Romero, Julia
name: Indeewari K.S. Lindamulage
name: Knockleby, James
name: Hoyun Lee
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology
subject: Computational Biology

description: The co-regulation of DNA replication and gene transcription is still poorly understood. To gain a better understanding of this important control mechanism, we examined the DNA replication and transcription using the Dbf4 origin-promoter and Dbf4 pseudogene models. We found that origin firing and Dbf4 transcription activity were inversely regulated in a cell cycle-dependent manner. We also found that proteins critical for the regulation of replication (ORC, MCM), transcription (SP1, TFIIB), and cohesin (Smc1, Smc3) and Mediator functions (Med1, Med12) interact with specific sites within and the surrounding regions of the Dbf4 locus in a cell cycle-dependent manner. As expected, replication initiation occurred within a nucleosome-depleted region, and nucleosomes flanked the 2 replication initiation zones. Further, the histone H3 in this region was distinctly acetylated or trimethylated on lysine 9 in a cell cycle-dependent fluctuation pattern: H3K9ac was most prevalent when the Dbf4 transcription level was highest whereas the H3K9me3 level was greatest during and just after replication. The KDM4A histone demethylase, which is responsible for the H3K9me3 modification, was enriched at the Dbf4 origin in a manner coinciding with H3K9me3. Finally, HP1γ, a protein known to interact with H3K9me3 in the heterochromatin was also found enriched at the origin during DNA replication, indicating that H3K9me3 may be required for the regulation of replication at both heterochromatin and euchromatin regions. Taken together, our data show that mammalian cells employ an extremely sophisticated and multilayered co-regulation mechanism for replication and transcription in a highly coordinated manner.
Additional file 5 of Healthcare provider perspectives on integrating peer support in non-dialysis-dependent chronic kidney disease care: a mixed methods study
Creators: name: Love, Shannan
name: Harrison, Tyrone G.
name: Fox, Danielle E.
name: Donald, Maoliosa
name: Verdin, Nancy
name: Hemmelgarn, Brenda R.
name: Elliott, Meghan J.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Molecular Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 5. Characteristics of peer support processes: description of clinic processes from respondents indicating peer support awareness.
Regulation of AURORA B function by mitotic checkpoint protein MAD2
Creators: name: Jayasha Shandilya
name: Medler, Kathryn F.
name: Roberts, Stefan G. E.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Developmental Biology
subject: Cancer

description: Cell cycle checkpoint signaling stringently regulates chromosome segregation during cell division. MAD2 is one of the key components of the spindle and mitotic checkpoint complex that regulates the fidelity of cell division along with MAD1, CDC20, BUBR1, BUB3 and MAD3. MAD2 ablation leads to erroneous attachment of kinetochore-spindle fibers and defective chromosome separation. A potential role for MAD2 in the regulation of events beyond the spindle and mitotic checkpoints is not clear. Together with active spindle assembly checkpoint signaling, AURORA B kinase activity is essential for chromosome condensation as cells enter mitosis. AURORA B phosphorylates histone H3 at serine 10 and serine 28 to facilitate the formation of condensed metaphase chromosomes. In the absence of functional AURORA B cells escape mitosis despite the presence of misaligned chromosomes. In this study we report that silencing of MAD2 results in a drastic reduction of metaphase-specific histone H3 phosphorylation at serine 10 and serine 28. We demonstrate that this is due to mislocalization of AURORA B in the absence of MAD2. Conversely, overexpression of MAD2 concentrated the localization of AURORA B at the metaphase plate and caused hyper-phosphorylation of histone H3. We find that MAD1 plays a minor role in influencing the MAD2-dependent regulation of AURORA B suggesting that the effects of MAD2 on AURORA B are independent of the spindle checkpoint complex. Our findings reveal that, in addition to its role in checkpoint signaling, MAD2 ensures chromosome stability through the regulation of AURORA B.
Additional file 6 of Healthcare provider perspectives on integrating peer support in non-dialysis-dependent chronic kidney disease care: a mixed methods study
Creators: name: Love, Shannan
name: Harrison, Tyrone G.
name: Fox, Danielle E.
name: Donald, Maoliosa
name: Verdin, Nancy
name: Hemmelgarn, Brenda R.
name: Elliott, Meghan J.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Molecular Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 6. Likert scale responses: responses to Likert scale questions about perceived need, interest, and impact of peer support.
АНАЛИТИЧЕСКИЙ ОБЗОР ФАКТОРОВ ЭФФЕКТИВНОЙ ЭКСПЛУАТАЦИИ МОРСКОГО ТРАНСПОРТА
Creators: name: О. А. Белов
Publisher: name: Техническая эксплуатация водного транспорта: проблемы и пути развития
Year: 2019
Subjects: эффективность
техническая эксплуатация
судоремонт
автоматизация
техническое обслуживание
человеческий фактор
подготовка специалистов.

description: Эффективная эксплуатация морского транспорта является необходимым условием развития как отдельных отраслей народного хозяйства, так и экономики страны в целом. В широком смысле эффективность эксплуатации морского транспорта подразумевает не только приемлемые экономические показатели, но и обеспечение безопасности плавания, безаварийности, а также экологической безопасности. Определение и анализ основополагающих факторов эффективной эксплуатации морского транспорта, а также их качественная оценка применительно к обеспечению условий эксплуатации являются актуальной задачей.
Face/Off: changing the face of movies with deepfakes
Creators: name: Murphy, Gillian
name: Ching, Didier
name: Twomey, John
name: Linehan, Conor
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 46
subject: Information and computing sciences

description: There are growing concerns about the potential for deepfake technology to spread misinformation and distort memories, though many also highlight creative applications such as recasting movies using other actors, or younger versions of the same actor. In the current mixed-methods study, we presented participants (N = 436) with deepfake videos of fictitious movie remakes (such as Will Smith staring as Neo in The Matrix). We observed an average false memory rate of 49%, with many participants remembering the fake remake as better than the original film. However, deepfakes were no more effective than simple text descriptions at distorting memory. Though our findings suggest that deepfake technology is not uniquely placed to distort movie memories, our qualitative data suggested most participants were uncomfortable with deepfake recasting. Common concerns were disrespecting artistic integrity, disrupting the shared social experience of films, and a discomfort at the control and options this technology would afford.
РЫБОЛОВНЫЙ ФЛОТ В СТАТИСТИКЕ ЕВРОПЕЙСКОГО АГЕНТСТВА МОРСКОЙ БЕЗОПАСНОСТИ
Creators: name: С. В. Ермаков
Publisher: name: Техническая эксплуатация водного транспорта: проблемы и пути развития
Year: 2019
Subjects: аварийность
статистика
Европейское агентство морской безопасности.

description: В статье представлены актуальные статистические данные по аварийности судов, полученные Европейским агентством морской безопасности по результатам анализа большого массива отчетов о расследовании морских аварий и инцидентов и иных источников, а также анализ этих данных с акцентом на место в аварийности рыболовного флота. Представленный материал является частью эмпирической базы для сравнительного анализа и оценки аварийности отечественных рыбопромысловых судов.
ПЕРСПЕКТИВЫ E-НАВИГАЦИИ В СУДОВОЖДЕНИИ
Creators: name: А. И. Жгулев
name: Е. В. Чабанова
Publisher: name: Техническая эксплуатация водного транспорта: проблемы и пути развития
Year: 2019
Subjects: e-Навигация
судовождение
безопасность
транспортная система
план внедрения.

description: E-Навигация является сегодня одним из наиболее перспективных направлений применения новых, инновационных технологий в области морского и речного транспорта. С одной стороны, можно говорить, что это – часть общей тенденции к автоматизации управления транспортом, созданию интеллектуальных транспортных систем, которая наблюдается и в других видах транспорта: автомобильном, авиационном, железнодорожном. С другой стороны – происходит своеобразная революция, качественный скачок, связанный с проникновением самых передовых информационных технологий, таких как BigData и InternetofThings в морскую отрасль, которая традиционно отставала от остальных отраслей в применении ИТ.
Additional file 1 of A Learning Healthcare System for pregnant and breastfeeding women: what do women during preconception, pregnancy, and nursing think? – A qualitative study
Creators: name: Hollestelle, Marieke J.
name: van der Graaf, Rieke
name: Hartman, Sarah Dewi
name: Sturkenboom, Miriam C. J. M.
name: van Delden, Johannes J. M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1.
Association of TNF-α rs1799964 and IL-1β rs16944 polymorphisms with multiple system atrophy in Chinese Han population
Creators: name: Zhou, Xin
name: Wang, Chunrong
name: Chen, Zhao
name: Peng, Yun
name: Peng, Huirong
name: Hou, Xuan
name: Ye, Wei
name: Qiu, Rong
name: Xia, Kun
name: Tang, Beisha
name: Jiang, Hong
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Background: Recent evidence suggested that several single nucleotide polymorphisms (SNPs) of inflammation-related genes (TNF-α rs1799964, IL-1α rs1800587, IL-1β rs16944, IL-8 rs4073, ICAM-1 rs5498) were associated with multiple system atrophy (MSA). Herein, we conducted this case-control study to evaluate the possible correlation between the five SNPs related to inflammation and MSA in Chinese Han population. Methods and Patients: We recruited 154 sporadic patients with MSA and 223 health controls in this study. All subjects were genotyped for the five SNPs using polymerase chain reaction amplification and Sanger sequencing. Results: TNF-α rs1799964, genotype distribution and minor allele frequency (MAF) showed significant differences between patients and controls, which might illustrate the minor allele C may increase the risk for MSA (genotype, P = 0.006, OR = 1.245, 95% CI = [1.066–1.455]; allele, P = 0.001, OR = 1.887, 95% CI = [1.303–2.733]). For rs16944, patients carrying AA genotype showed a nearly 5-year early age at onset (AAO) than GG genotype (50.52 ± 7.45 years vs. 54.90 ± 7.21 years, P = 0.037). No differences were found in genotype distribution and MAF of the five SNPs between patients with MSA with predominant cerebellar ataxia (MSA-C) and with predominant Parkinsonism (MSA-P). Conclusion: Our study suggests that rs1799964 of TNF-α may act as a risk factor for MSA and the IL-1β rs16944 might be a genetic factor that modifies the AAO in MSA. Moreover, the exact mechanism of neuroinflammatory response in MSA deserves further exploration.
Additional file 10 of An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse
Creators: name: Bartsch, Lorenz
name: Schroeder, Michael P.
name: Hänzelmann, Sonja
name: Bastian, Lorenz
name: Lázaro-Navarro, Juan
name: Schlee, Cornelia
name: Tanchez, Jutta Ortiz
name: Schulze, Veronika
name: Isaakidis, Konstandina
name: Rieger, Michael A.
name: Gökbuget, Nicola
name: Eckert, Cornelia
name: Serve, Hubert
name: Horstmann, Martin
name: Schrappe, Martin
name: Brüggemann, Monika
name: Baldus, Claudia D.
name: Neumann, Martin
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 10. Wildtype CYB5A mRNA expression is lower in pCYB5Aalt NALM-6 than in empty vector controls. Relative mRNA expression measured by qRT-PCR is depicted as ΔCT(GAPDH-CYB5A). GAPDH was used as reference gene. Red dots represent mean expression of pCYB5Aalt NALM-6 (n = 11, mean = − 7.24) and empty vector controls (n = 3, mean = − 6.61). Red lines show standard error of the mean (pCYB5Aalt NALM-6: ±0.185, empty vector controls: ±0.063). The maximum and minimum expression value of CYB5Aalt clones were defined as outliers and excluded from statistical analysis. Mean expression was compared using both-sided t-test (p = 0.01).
DEEP-SEA, MIDDLE-WATER AND INSHORE FISHING
Creators: name: V. A. Yamschikov
name: A. M. Sarancha
Publisher: name: Техническая эксплуатация водного транспорта: проблемы и пути развития
Year: 2019
Subjects: seaman
fish
fishing
water
shore
deep-sea
inshore.

description: The present article is devoted to the peculiarities of deep-sea, middle-water and inshore fishing and describes the function of fishermen during dangerous conditions in open sea. Настоящая статья посвящена особенностям глубоководной, мелководной и прибрежной рыбной ловли, а также освещает функции рыбаков, находящихся в опасных
Christoph Jamnitzer's Neuw Grotteßken Buch, Cosmography, and Early Modern Ornament
Creators: name: Viljoen, Madeleine C.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Prefaced by a narrative about the cosmographo Christopher Columbus, Christoph Jamnitzer's Neuw Grotteßken Buch (1610) offers an important means to understand how the art of decorative printmaking was construed in terms of contemporary cosmography. By studying the book's grotesque imagery in light of the language of its introductory text, it is possible to think about ornament in its early seventeenth-century author's terms, and to reflect on the genre outside the problems of style and function that have preoccupied scholars since the nineteenth century. Christoph's book provides access to features of a previously overlooked discourse on early modern ornament.
Additional file 11 of An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse
Creators: name: Bartsch, Lorenz
name: Schroeder, Michael P.
name: Hänzelmann, Sonja
name: Bastian, Lorenz
name: Lázaro-Navarro, Juan
name: Schlee, Cornelia
name: Tanchez, Jutta Ortiz
name: Schulze, Veronika
name: Isaakidis, Konstandina
name: Rieger, Michael A.
name: Gökbuget, Nicola
name: Eckert, Cornelia
name: Serve, Hubert
name: Horstmann, Martin
name: Schrappe, Martin
name: Brüggemann, Monika
name: Baldus, Claudia D.
name: Neumann, Martin
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 11. Sample-to-sample distance between pCYB5Aalt NALM-6 and Empty Vector controls by Principal Component Analysis. Principal component analysis of rlog normalised RNAseq counts from pCYB5Aalt Nalm 6 cells (n = 4) and Empty Vector controls (n = 2) identifies different clusters. Empty vector controls define one cluster (bottom right). Three pCYB5Aalt NALM-6 clones define another (top middle). The fourth pCYB5Aalt clone was treated as an outlier and not included in further analysis.
БЕСПИЛОТНЫЕ ЛЕТАТЕЛЬНЫЕ АППАРАТЫ
Creators: name: В. А. Ямщиков
name: А. М. Саранча
Publisher: name: Техническая эксплуатация водного транспорта: проблемы и пути развития
Year: 2019
Subjects: дрон
БПЛА
человек
тревога
наблюдение.

description: В статье рассматривается возможность замены наблюдателя во время тревоги «Человек за бортом» на БПЛА. Предполагается снабдить судно дроном вертолетного типа, который может взлетать с площадки размером не более 5×5 метров и имеет целевую нагрузку в виде тепловизора и видеокамеры.
A rapid, mild, and efficient method for C-5 iodination/thiocyanation of 2-aminothiazoles
Creators: name: Hebade, Madhav J.
name: Kamble, Rahul D.
name: Shrikant V. Hese
name: Mogle, Pratima P.
name: Ambhore, Ajay N.
name: Shuddhodan N. Kadam
name: Dawane, Bhaskar S.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: An efficient, green, rapid multitasking protocol for the selective C-5 substitution of 2-aminothiazole using iodic acid and aqueous PEG-400 was developed. The method found suitable for C-5 substitution i.e. iodination and thiocyanation of 2-amino thiazole using iodine and ammonium thiocyanate respectively. Iodic acid was found to be a good oxidant and aqueous PEG-400 as green reaction solvent.
Additional file 12 of An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse
Creators: name: Bartsch, Lorenz
name: Schroeder, Michael P.
name: Hänzelmann, Sonja
name: Bastian, Lorenz
name: Lázaro-Navarro, Juan
name: Schlee, Cornelia
name: Tanchez, Jutta Ortiz
name: Schulze, Veronika
name: Isaakidis, Konstandina
name: Rieger, Michael A.
name: Gökbuget, Nicola
name: Eckert, Cornelia
name: Serve, Hubert
name: Horstmann, Martin
name: Schrappe, Martin
name: Brüggemann, Monika
name: Baldus, Claudia D.
name: Neumann, Martin
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 12. Gene set enrichment analysis identifying differentially expressed pathways between pCYB5Aalt NALM-6 cells and Empty Vector controls. Gene set enrichment analysis was performed using the log2 foldchange/standard error of log2 foldchange between the transcriptional profiles of pCYB5Aalt and Empty Vector samples. A NES for MsigDB Hallmark pathways (n = 50) is displayed in a descending order, positive scores implying an upregulation. Pathways with a FDR
ИЗМЕНЕНИЕ РАБОЧИХ ПАРАМЕТРОВ СУДОВОГО ОХЛАДИТЕЛЯ МАСЛА ПРИ НЕСТАЦИОНАРНЫХ НАГРУЗКАХ ГЛАВНОГО ТУРБОЗУБЧАТОГО АГРЕГАТА В УСЛОВИЯХ ЭКСПЛУАТАЦИИ
Creators: name: А. Р. Аблаев
Publisher: name: Техническая эксплуатация водного транспорта: проблемы и пути развития
Year: 2019
Subjects: охладитель масла
тепловой режим работы
регулирование температуры.

description: Приведен анализ изменения рабочих характеристик судового охладителя масла при использовании различных способов регулирования температурных режимов охладителей. При этом учитываются изменения тепловых нагрузок от главной двигательной установки в процессе его эксплуатации.
РАЗРАБОТКА МЕРОПРИЯТИЙ ПО ЗАЩИТЕ КОРПУСОВ СУДОВ ОТ ЭЛЕКТРОКОРРОЗИИ НА СУДОРЕМОНТНЫХ ПРЕДПРИЯТИЯХ
Creators: name: О. А. Белов
name: В. А. Швецов
name: Д. П. Ястребов
name: В. А. Ветров
name: А. Д. Щелканов
name: И. И. Бондарчук
Publisher: name: Техническая эксплуатация водного транспорта: проблемы и пути развития
Year: 2019
Subjects: электрокоррозия
контроль защищенности корпусов судов
электросварочные работы
дренажный провод
причальная стенка.

description: Выполнение действующих нормативных требований по защите корпуса судна от электрокоррозии вызывает значительные затруднения при выполнении судоремонтных работ и эксплуатации судна. Авторами предложены дополнительные организационно-технические мероприятия по защите корпусов судов от электрокоррозии. Приведены результаты исследований защищенности судов от электрокоррозии при выполнении судоремонтных работ, из которых следует, что от выполнения действующих жестких нормативных требований можно во многих случаях отказаться. Для этого следует усовершенствовать оперативный контроль значений переменного напряжения и плотности переменного тока в процессе выполнения электросварочных работ.
THE IMPORTANCE OF THE SUBJECT OF GEOGRAPHY IN DEVELOPING ECOLOGICAL KNOWLEDGE IN PUPILS
Creators: name: Nurlanov, A.S.
Publisher: name: Zenodo
Year: 2024

description: Due to the drying up of the Aral Sea, the ecological disaster on the territory of the Republic of Karakalpakstan has aggravated and led to negative changes in the environment, and significantly affected all sectors of the economy. This article considers the role of geography in the formation of environmental education and skills in schoolchildren of Karakalpakstan.
The ceramide-activated protein phosphatase Sit4p controls lifespan, mitochondrial function and cell cycle progression by regulating hexokinase 2 phosphorylation
Creators: name: Barbosa, António Daniel
name: Pereira, Clara
name: Osório, Hugo
name: Moradas-Ferreira, Pedro
name: Costa, Vítor
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Sit4p is the catalytic subunit of a ceramide-activated PP2A-like phosphatase that regulates cell cycle, mitochondrial function, oxidative stress resistance and chronological lifespan in yeast. In this study, we show that hexokinase 2 (Hxk2p) is hyperphosphorylated in sit4Δ mutants grown in glucose medium by a Snf1p-independent mechanism and Hxk2p-S15A mutation suppresses phenotypes associated with SIT4 deletion, namely growth arrest at G1 phase, derepression of mitochondrial respiration, H2O2 resistance and lifespan extension. Consistently, the activation of Sit4p in isc1Δ mutants, which has been associated with premature aging, leads to Hxk2p hypophosphorylation, and the expression of Hxk2p-S15E increases the lifespan of isc1Δ cells. The overall results suggest that Hxk2p functions downstream of Sit4p in the control of cell cycle, mitochondrial function, oxidative stress resistance and chronological lifespan.
Modeling Lemur Vocalizations from a Signal Processing Perspective
Creators: name: Porcaro, Lorenzo
Publisher: name: Zenodo
Year: 2015
Subjects: Bioacoustics
Speech Processing
Hidden Markov Model

description: Most of the synthesis models for the generation of the animal vocalization until now have been studied with a non-probabilistic approach. Current studies are based on physical models, which have a large number of restrictions and limits for the creation of a realistic synthesis. In this thesis, we have created acoustic representations of black and white ruffed lemur (Varecia variegata) vocalizations, basing on signal processing techniques, and we have used them for achieving high-level synthesis. Afterwards, we have introduced Hidden Markov Models framework, approach which has been very successful in the context of speech synthesis. The outcome of the project has been evaluated by means of listening tests with humans, where original and synthetic vocalizations have been evaluated.
Additional file 13 of An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse
Creators: name: Bartsch, Lorenz
name: Schroeder, Michael P.
name: Hänzelmann, Sonja
name: Bastian, Lorenz
name: Lázaro-Navarro, Juan
name: Schlee, Cornelia
name: Tanchez, Jutta Ortiz
name: Schulze, Veronika
name: Isaakidis, Konstandina
name: Rieger, Michael A.
name: Gökbuget, Nicola
name: Eckert, Cornelia
name: Serve, Hubert
name: Horstmann, Martin
name: Schrappe, Martin
name: Brüggemann, Monika
name: Baldus, Claudia D.
name: Neumann, Martin
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 13. Gene set enrichment analysis comparing CYB5Aalt-positive and CYB5A WT samples in the NH/HeH gene expression cluster shows similar downregulated pathways to the overexpression cell line. Gene set enrichment analysis was performed between CYB5Aalt-positive samples (n = 15) and CYB5A WT samples (n = 7) in the NH/HeH cluster (n = 22) of combined cohort 3. NES for MsigDB Hallmark pathways (n = 50) is shown with positive scores implying an upregulation in CYB5Aalt-positive samples. Pathways with a FDR
Effects of new ways of working on work hours and work location, health and job-related outcomes
Creators: name: Hylco H. Nijp
name: Beckers, Debby G. J.
name: Voorde, Karina Van De
name: Geurts, Sabine A. E.
name: Kompier, Michiel A. J.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology

description: New ways of working (NWW) is a type of work organization that is characterized by temporal and spatial flexibility, often combined with extensive use of information and communication technologies (ICT) and performance-based management. In a three-wave intervention study, we examined the effects of NWW on both the organization of work (changes in control over time and place of work; working hours and work location; and other key job characteristics), and on employees’ outcomes (work–nonwork balance; health and well-being; and job-related outcomes). We applied a quasi-experimental design within a large Dutch financial company (N = 2,912). We studied an intervention group (n = 2,391) and made comparisons with a reference group (n = 521). There were three study waves: (i) one/two months before, and (ii) 4 months and (iii) 10 months after implementation of NWW. Repeated measures analyses of covariance (involving 361 participants from the intervention group and 80 participants from the reference group) showed a large and significant shift from hours worked at the office to hours worked at home after implementation of NWW. Accordingly, commuting time was reduced. Employees remained working on week days and during day time. Psychosocial work-characteristics, work–nonwork balance, stress, fatigue, and job-related outcomes remained favourable and largely unaffected, but the health score in the intervention group decreased (medium effect). These findings suggest that the implementation of NWW does not necessarily lead to changes in psychosocial work characteristics, well-being or job-related outcomes.
Effectiveness of lowering the blood alcohol concentration (BAC) limit for driving from 0.10 to 0.08 grams per deciliter in the United States
Creators: name: Scherer, Michael
name: C. Fell, James
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Objective: The current study evaluates of the effects of lowering the blood alcohol concentration (BAC) limit from 0.10 to 0.08 g/dL across all 50 states in the United States. Our objectives were to (1) estimate the effects of the 0.08 g/dL BAC limit on drinking driver fatal crash rates; (2) compare the effects from early-adopting states to the effects of late-adopting states; (3) determine the effects on drivers with low BACs (0.01–0.07 g/dL) and high BACs (0.08+ g/dL); and (4) estimate the lives saved since 1983 due to the adoption of 0.08 g/dL BAC laws. Methods: Our study examined annual data from the Fatality Analysis Reporting System (FARS) for each jurisdiction from 1982 through 2014. Our basic outcome measure was the ratio of drinking drivers (BAC ≥0.01 g/dL) to nondrinking drivers (BAC = 0.00 g/dL). Covariates included 0.10 BAC laws, administrative license revocation (ALR) laws, seat belt laws, minimum legal drinking age (MLDA) laws, and unemployment rates. We utilized autoregressive integrated moving average (ARIMA) models for each state, where the implementation date of the law was modeled as a zero-order transfer function in the series, in addition to any extant trends that may have been occurring simultaneously. Before determining the specific impact of the implementation of 0.08 g/dL BAC laws, we conducted a time series analysis for each state. We tested for between-state mediating factors relating to our covariates. Results: A total of 38 of the 51 jurisdictions showed that lowering the BAC limit was associated with reduced drinking driver fatal crash ratios, with 20 of those reductions being significant. The total effects showed a 10.4% reduction in annual drinking driver fatal crash rates, which is estimated to have saved an average of 1,736 lives each year between 1983 and 2014 and 24,868 lives in total. Implementing a BAC limit of 0.08 g/dL had significant impacts on both high- and low-BAC fatal crash ratios. Though early-adopting jurisdictions (1983–1999) demonstrated a larger decrease in fatal drinking driver crash ratios than did late-adopting jurisdictions (2000–2005), the results were not statistically significant (P > .05). Conclusions: Our study of the effects of lowering the BAC from 0.10 to 0.08 g/dL in the United States from 1982 to 2014 showed an overall effect of 10.4% on annual drinking driver fatal crash rates, in line with other multistate studies. This research provides strong evidence of the relationship between lowering the BAC limit for driving and the general deterrent effect on impaired-driving fatal crash rates.
Bibliometric analysis of simulated driving research from 1997 to 2016
Creators: name: Guo, Fu
name: Lv, Wei
name: Liu, Li
name: Wang, Tianbo
name: Duffy, Vincent G.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: Information Systems not elsewhere classified
Science Policy

description: Objective: The objective of this study was to explore the evolution footprints of simulated driving research in the past 20 years through rigorous and systematic bibliometric analysis, to provide insights regarding when and where the research was performed and by whom and how the mainstream content evolved over the years. Methods: The analysis began with data retrieval in Web of Science with defined search terms related to simulated driving. BibExcel and CiteSpace were employed to conduct the performance analysis and co-citation network analysis; that is, probe of the performance of institutes, journals, authors, and research hotspots. Results: A total of 3,766 documents were filtered out and presented an exponential growth from 1997 to 2016. The United States contributed the most publications as well as international collaborations followed by Germany and China. In addition, several universities in The Netherlands and the United States dominated the list of contributing institutes. The leading journals were in transportation and ergonomics. The leading researchers were also recognized among the 8,721 contributing authors, such as J. D. Lee, D. L. Fisher, J. H. Kim, and K. A. Brookhuis. Finally, the co-citation analysis illuminated the evolution of simulated driving research that covered the following topics roughly in chronological order: task-induced stress, drivers with neurological disorders, alertness and sleepiness while driving, trust toward driving assistance systems, driver distraction, the effect of drug use, the validity of simulators, and automated driving. Conclusions: This article employed bibliometric tools to probe the contributing countries, institutes, journals, authors, and mainstream hotspots of simulated driving research in the past 20 years. A systematic bibliometric analysis of this field will help researchers realize the panorama of global simulated driving and establish future research directions.
Ventilation mode changes our safety in buses: Study on “air-rain” flow against chemical and arson attack in public transport vehicles
Creators: name: Chen, Ning
name: Kozinski, Janusz
name: Tan, Yamin
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Objectives: Public transport vehicles (PTVs) play a decisive role in development of the urban economy. However, the safety of PTVs is threatened by the man-released chemical or arson attack. It was found that indoor air safety can be greatly improved by employing air-rain ventilation instead of the common ventilation in a PTV. Methods: Numerical simulations and experiments have been done to prove the effectiveness of the air-rain flow against chemical attack or arson in PTVs. Results: The research shows that, during a chemical attack, an air-rain flow of 0.1 m/s can constrain the spread of a chemical agent in a very limited zone near its source, which is far away from the passengers’ breathing area in the PTV. During an arson attack, at an air-rain flow of 0.3 m/s, most of the area in the PTV maintains a low temperature for at least 60 s during a fire, which is long enough for passenger evacuation. Conclusion: Compared to common ventilation, the key characteristic of air-rain ventilation is its resistance to the blending effect of the air. Because of this, the spread of chemical agents, hot gas/combustion products during a fire, and fuel aerosol is constrained to a limited area in a PTV. Passengers are then protected from chemical attack, explosion of fuel aerosols, and high temperatures and smoke. Thus, we can say that this new ventilation mode increases passenger safety in buses.
Integrity® bare-metal coronary stent-induced platelet and endothelial cell activation results in a higher risk of restenosis compared to Xience® everolimus-eluting stents in stable angina patients
Creators: name: Szük, Tibor
name: Fejes, Zsolt
name: Debreceni, Ildikó Beke
name: Kerényi, Adrienne
name: Édes, István
name: Kappelmayer, János
name: Nagy, Béla
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology
subject: Computational Biology

description: Drug-eluting stenting (DES) has become a reliable tool for coronary stenting; however, its direct effects on platelet and endothelium function differ from those of bare-metal stenting (BMS). This study involved a periprocedural analysis of various biomarkers of cellular activation after elective DES (Xience®, Abbott Vascular, Santa Clara, CA, USA) or BMS (Integrity®, Medtronic, Minneapolis, MI, USA). Forty-nine stable angina patients were recruited: 28 underwent BMS, and 21 received everolimus-eluting stents. Samples were collected (i) prior to stenting, (ii) at 24 hours after procedure, and (iii) after 1 month of dual antiplatelet therapy. Platelet activation was analyzed by surface P-selectin positivity in parallel with plasma levels of soluble P-selectin, CD40L and platelet-derived growth factor (PDGF). Endothelial cell (EC) activation was detected by measuring markers of early (von Willebrand factor) and delayed response (VCAM-1, ICAM-1, E-selectin). Patients were followed for 6 months for the occurrence of restenosis or stent thrombosis. Increased platelet activation was sustained regardless of stent type or antiplatelet medication. Concentrations of most EC markers were more elevated after BMS than after DES. No stent thrombosis was seen, but six BMS subjects displayed restenosis with significantly higher sCD40L (779 [397–899] vs. 381 [229–498] pg/mL; p = 0.032) and sICAM-1 (222 [181–272] vs. 162 [153–223] ng/mL; p = 0.046) levels than in those without complication, while DES patients exhibited significantly decreased PDGF (572 [428–626] vs. 244 [228–311] pg/mL; p = 0.004) after 1 month. Nonresponsiveness to antiplatelet drugs did not influence these changes. In conclusion, the degree of platelet and EC activation suggests that Xience® DES may be regarded a safer coronary intervention than Integrity® BMS, with a lower risk of in-stent restenosis.
Additional file 14 of An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse
Creators: name: Bartsch, Lorenz
name: Schroeder, Michael P.
name: Hänzelmann, Sonja
name: Bastian, Lorenz
name: Lázaro-Navarro, Juan
name: Schlee, Cornelia
name: Tanchez, Jutta Ortiz
name: Schulze, Veronika
name: Isaakidis, Konstandina
name: Rieger, Michael A.
name: Gökbuget, Nicola
name: Eckert, Cornelia
name: Serve, Hubert
name: Horstmann, Martin
name: Schrappe, Martin
name: Brüggemann, Monika
name: Baldus, Claudia D.
name: Neumann, Martin
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 14. Expression of BH3-motif genes in engineered cell lines and combined cohort 3. BH3-motif genes are subdivided according to their reported roles in apoptosis in pro-apoptotic (BAD, BID, BCL2L11), anti-apoptotic (BCL2, BCL2L2, BCL2A1) and isoform-dependent (MCL1, BCL2L1). A BH3-motif gene expression (in TPM) is compared between pCYB5Aalt NALM-6 (n = 3) and empty vector controls (n = 2). Dots represent expression of individual clones. B Gene expression is compared between samples positive for CYB5Aalt (n = 22) and negative samples (n = 198) in combined cohort 3 (n = 220). Dots represent mean expression; vertical lines show standard error of mean. FDR = false discovery rate (Benjamini-Hochberg method).
Additional file 1 of Antibiotic affects the gut microbiota composition and expression of genes related to lipid metabolism and myofiber types in skeletal muscle of piglets
Creators: name: Yan, Honglin
name: Yu, Bing
name: Degroote, Jeroen
name: Spranghers, Thomas
name: Van Noten, Noémie
name: Majdeddin, Maryam
name: Van Poucke, Mario
name: Peelman, Luc
name: De Vrieze, Jo
name: Boon, Nico
name: Gielen, Ingrid
name: Smet, Stefaan De
name: Chen, Daiwen
name: Michiels, Joris
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Computational Biology

description: Additional file 1.
ПОВЫШЕНИЕ ТЕПЛООТДАЧИ ЗАМКНУТЫХ ОДНОКОНТУРНЫХ СИСТЕМ ОХЛАЖДЕНИЯ СУДОВЫХ ЭНЕРГЕТИЧЕСКИХ УСТАНОВОК
Creators: name: Д. О. Владецкий
name: А. О. Харченко
name: Е. А. Владецкая
Publisher: name: Техническая эксплуатация водного транспорта: проблемы и пути развития
Year: 2019
Subjects: система охлаждения СЭУ
погружной теплообменный аппарат
интенсификация теплоотдачи.

description: Приведены результаты теплотехнических исследований теплоотдачи в погружном пластинчатом теплообменном аппарате при использовании газожидкостных струй для интенсификации теплоотдачи в замкнутых одноконтурных системах охлаждения CЭУ.
A theoretical investigation on the electronic structures and phosphorescent properties of three heteroleptic iridium(III) complexes with different substituted ancillary groups
Creators: name: Deming Han
name: Xiaogang Wang
name: Lihui Zhao
name: Chunying Pang
name: Qingshuang Wang
name: Zhang, Gang
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Three heteroleptic iridium(III) complexes 1, 2 and 3 bearing two cyclometalating 2′,6′-difluoro-2,3′-bipyridyl (dfpypy) chelates and one pyridyl pyrazolate ligand have been investigated by using the density functional theory/time-dependent density functional theory method to study the influence of the different substituent groups (―CF3 and ―N(CH3)2 moiety on the electronic structures, phosphorescent properties and the organic light-emitting diode performance. The lowest energy absorption wavelength calculated is in good agreement with the experimental value. The lowest energy emissions of complexes 1, 2 and 3 are localised at 454, 534 and 821 nm, respectively. Ionisation potential and electron affinity have been calculated to evaluate the injection abilities of holes and electrons into these complexes. The calculated results show that the different substitute groups affect the charge transfer rate and balance. Finally, we hope that this study can provide a good guide to the future design and synthesis of novel phosphorescent materials for use in the organic light-emitting diodes.
ЭКСЕРГЕТИЧЕСКИЙ БАЛАНС ВЫСОКОФОРСИРОВАННЫХ СУДОВЫХ СРЕДНЕОБОРОТНЫХ ДВИГАТЕЛЕЙ
Creators: name: М. С. Дрозд
Publisher: name: Техническая эксплуатация водного транспорта: проблемы и пути развития
Year: 2019
Subjects: эксергетический баланс
термодинамический анализ
среднеоборотный двигатель
вторичные энергоресурсы
тепловые потери.

description: В определении составляющих теплового баланса судовых ДВС существенное место занимают энер-гетические превращения, определяемые первым и вторым законами термодинамики. Однако традицион-ные методы определения энергетических балансов имеют существенные недостатки: они не учитывают качественных различий энергоресурсов и особенностей процессов функционирования, обусловленных их необратимостью, а также не учитывают внешние потери. Преодолеть эти недостатки можно путем приме-нения эксергетического подхода к анализу термодинамических процессов.