cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Cadernos de Saúde, v. 4 n. Especial (2011): Obesidade
title: Obesidade
titleType: AlternativeTitle
Creators: name: Cadernos De Saúde
Publisher: name: Cadernos de Saúde
Year: 2011

description: Editorial...7-7 Programa da reunião “Obesidade – uma visão multidisciplinar” 2 e 3 de Julho de 2010...9-10 Determinantes da epidemia mundial da obesidade...11-13 Responsabilidade da indústria alimentar, de distribuição e marketing na prevenção da obesidade...15-20 A plataforma contra a obesidade e o Plano Nacional de Saúde...21-25 Obesidade infantil: uma epidemia à escala mundial...27-32 Factores sociais na obesidade...33-36 Introdução à mesa-redonda sobre fisiopatologia da obesidade...37-37 O adipócito como uma célula auto-reguladora...39-43 Inflamação na obesidade...45-48 O balão intra‑gástrico no tratamento da obesidade...49-54 Obesidade: uma visão multidisciplinar...55-57 Obesidade e cirurgia bariátrica: perspectiva multidisciplinar...59-60 A consulta de Nutrição no pré e pós‑operatório para tratamento da obesidade: Hospital da Prelada Dr. Domingos Braga da Cruz...61-64 Consulta de Psicologia no per‑operatório da obesidade...65-67 Contra-indicações psiquiátricas na cirurgia bariátrica...69-73 Intervenção psicológica em grupos: os grupos de ensino e os grupos pós‑cirurgia no Hospital da Prelada...75-77 Dietas pós BG e BIG: prós e contras...79-81 O que há de novo na terapêutica médica da diabetes mellitus tipo 2?...83-87 Caracterização clínica dos doentes obesos em acompanhamento na consulta de Psicologia do Hospital da Prelada...89-90 Prevalência de excesso de peso e de obesidade em crianças do 1.º Ciclo do Ensino Básico...91-93 O balão intragástrico no tratamento da obesidade: análise de dois casos clínicos...95-96
Additional file 1 of Staff views on overdose prevention in permanent supportive housing
Creators: name: Doran, Kelly M.
name: Torsiglieri, Allison
name: Moran, Jocelyn
name: Blaufarb, Stephanie
name: Liu, Annie Y.
name: Ringrose, Emily
name: Urban, Cooper
name: Velez, Lauren
name: Hernandez, Patricia
name: O’Grady, Megan A.
name: Shelley, Donna
name: Cleland, Charles M.
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1
MyGene2 automated match report: KCNQ2
Creators: name: Team, The MyGene2
Publisher: name: figshare
Year: 2017
Subjects: subject: 110311 Medical Genetics (excl. Cancer Genetics)
subject: FOS: Basic medicine

description: MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If multiple MyGene2 profiles potentially match on a shared gene of interest, MyGene2 automatically generates a match report summarizing the information in these profiles. This automated match report is shared publicly to help facilitate further research and/or connections between the submitters of the MyGene2 profiles and other interested parties. This is an automated match report for KCNQ2.
2019 CANARIE RDM Workshop Notes and Resources
Creators: name: Leggott, Mark
name: Gerlitz, Laura
Publisher: name: Zenodo
Year: 2019
Subjects: subject: digital research infrastructure
subject: https://dictionary.casrai.org/Research_data_management
subject: https://dictionary.casrai.org/Data_management
subject: https://dictionary.casrai.org/Digital_infrastructure

description: Supplemental notes document for the Kanata Declaration.
Additional file 1 of Urinary metabolomic changes and microbiotic alterations in presenilin1/2 conditional double knockout mice
Creators: name: Gao, Jie
name: Zhou, Nian
name: Wu, Yongkang
name: Lu, Mengna
name: Wang, Qixue
name: Xia, Chenyi
name: Zhou, Mingmei
name: Xu, Ying
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Neuroscience
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Cancer
subject: Computational Biology

description: Additional file 1: Table S1. Differential metabolites between PS cDKO group and Control group at age of 2 months and 6 months.
RDM Workshop - Jan 23, 2019 Discussion Document
Creators: name: Leggott, Mark
name: Gerlitz, Laura
Publisher: name: Zenodo
Year: 2019
Subjects: subject: digital research infrastructure
subject: https://dictionary.casrai.org/Research_data_management
subject: https://dictionary.casrai.org/Data_management
subject: https://dictionary.casrai.org/Digital_infrastructure

description: Supplemental notes document for the Kanata Declaration.
National Data Services Framework Summit 2019 Notes and Resources
Creators: name: Leggott, Mark
name: Gerlitz, Laura
Publisher: name: Zenodo
Year: 2019
Subjects: subject: digital research infrastructure
subject: https://dictionary.casrai.org/Research_data_management
subject: https://dictionary.casrai.org/Data_management
subject: https://dictionary.casrai.org/Digital_infrastructure

description: Supplemental notes document for the Kanata Declaration.
A New Lens on High School Dropout: Use of Correspondence Analysis and the Statewide Longitudinal Data System
Creators: name: Ziemer, Kathryn Schaefer
name: Bianica Pires
name: Lancaster, Vicki
name: Keller, Sallie
name: Orr, Mark
name: Shipp, Stephanie
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: The combination of log-linear models and correspondence analysis have long been used to decompose contingency tables and aid in their interpretation. Until now, this approach has not been applied to the education Statewide Longitudinal Data System (SLDS), which contains administrative school data at the student level. While some research has been conducted using the SLDS, its primary use is for state education administrative reporting. This article uses the combination of log-linear models and correspondence analysis to gain insight into high school dropouts in two discrete regions in Kentucky, Appalachia and non-Appalachia, defined by the American Community Survey. The individual student records from the SLDS were categorized into one of the two regions and a log-linear model was used to identify the interactions between the demographic characteristics and the dropout categories, push-out and pull-out. Correspondence analysis was then used to visualize the interactions with the expanded push-out categories, boredom, course selection, expulsion, failing grade, teacher conflict, and pull-out categories, employment, family problems, illness, marriage, and pregnancy to provide insights into the regional differences. In this article, we demonstrate that correspondence analysis can extend the insights gained from SDLS data and provide new perspectives on dropouts. Supplementary materials for this article are available online.
Cadernos de Saúde, v. 4 n. 2 (2011)
Creators: name: Cadernos De Saúde
Publisher: name: Cadernos de Saúde
Year: 2011

description: Editorial...5-5 Afiliação universitária de Serviços de Cirurgia: uma solução para o ensino e um caminho para a academização dos cirurgiões...7-13 Cuidar da vertente espiritual em enfermagem : que sentido?...15-24 Estudos preliminares para a modelização de um avatar para a LGP: os descritores fonológicos...25-35 Adaptação cultural da Functional Assessment of Chronic ILLness Therapy -Spiritual Well -Being (FACIT-Sp): estudo de validaão em doentes oncológicos na fase final de vida...37-45 Optimização da anamnese em medicina dentária...47-55 Escala de Sobrecarga de Luto Profissional (SLP): construção e validação...57-64 Cultura Surda: a bandeira de um povo dentro de outro...65-70
Colleges/Institutes/Polytechnics Data Management Workshop
Creators: name: Leggott, Mark
Publisher: name: Zenodo
Year: 2019
Subjects: subject: college
subject: post-secondary institute
subject: canada
subject: polytechnic
subject: tri-agency policy
subject: https://dictionary.casrai.org/Research_data_management
subject: https://dictionary.casrai.org/Data_management
subject: https://dictionary.casrai.org/Open_data

description: Background and goals for the Canadian Colleges, Institutes & Polytechnics Research Data Management Workshop.
Additional file 1 of Elementary school compliance with a state recess minimum requirement by racial and geographic factors: a cross-sectional study
Creators: name: Howie, Erin K.
name: Harden, Samantha M.
name: Barr-Anderson, Daheia J.
name: Long, Christopher R.
Publisher: name: figshare
Year: 2025
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplementary Material 1
Additional file 1 of Association between multimorbidity patterns and disability among older people covered by long-term care insurance in Shanghai, China
Creators: name: Wang, Zijing
name: Peng, Wenjia
name: Li, Mengying
name: Li, Xinghui
name: Yang, Tingting
name: Li, Cancan
name: Yan, Huosheng
name: Jia, Xianjie
name: Hu, Zhi
name: Wang, Ying
Publisher: name: figshare
Year: 2021
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Additional file 1. The scree plot of the factor analysis, determining the number of retained factors.
Dataverse for the Canadian Research Community: Developing reusable and scalable tools for data deposit, curation, and sharing
Creators: name: Goodchild, Meghan
name: Leahey, Amber
name: Davis, Kate
Publisher: name: Zenodo
Year: 2019
Subjects: subject: national data services
subject: research data management
subject: canada
subject: digital research infrastructure
subject: dataverse
subject: https://dictionary.casrai.org/Research_data_management
subject: https://dictionary.casrai.org/Data_management
subject: https://dictionary.casrai.org/Digital_infrastructure
subject: https://dictionary.casrai.org/repository

description: Presentation on Dataverse. For the Research Data Management Workshop 2019.
The Perils of Balance Testing in Experimental Design: Messy Analyses of Clean Data
Creators: name: Mutz, Diana C.
name: Pemantle, Robin
name: Pham, Philip
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology

description: Widespread concern over the credibility of published results has led to scrutiny of statistical practices. We address one aspect of this problem that stems from the use of balance tests in conjunction with experimental data. When random assignment is botched, due either to mistakes in implementation or differential attrition, balance tests can be an important tool in determining whether to treat the data as observational versus experimental. Unfortunately, the use of balance tests has become commonplace in analyses of “clean” data, that is, data for which random assignment can be stipulated. Here, we show that balance tests can destroy the basis on which scientific conclusions are formed, and can lead to erroneous and even fraudulent conclusions. We conclude by advocating that scientists and journal editors resist the use of balance tests in all analyses of clean data. Supplementary materials for this article are available online
title: sainte Marine
Creators: name: Centre De Recherches Historiques / Anthropologie Historique Du Long Moyen Âge
Publisher: name: EHESS (School for Advanced Studies in Social Sciences)
Year: 2019

description: Entrée au monastère sous le nom de Marin pour accompagner son père, accusée d'avoir séduit une jeune fille, elle vit en pénitence jusqu'à sa mort en 750 ; représentée avec un froc de moine et un enfant nu dans les bras.
Additional file 1 of Differential brainstem connectivity according to sex and menopausal status in healthy male and female individuals
Creators: name: Kilpatrick, Lisa A.
name: Church, Arpana
name: Meriwether, David
name: Mahurkar-Joshi, Swapna
name: Li, Vince W.
name: Sohn, Jessica
name: Reist, Juliana
name: Labus, Jennifer S.
name: Dong, Tien
name: Jacobs, Jonathan P.
name: Naliboff, Bruce D.
name: Chang, Lin
name: Mayer, Emeran A.
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Cancer

description: Supplementary Material 1. Mean estrogen levels, with standard errors, in males, premenopausal females, and postmenopausal females. Plasma data is provided in units of ng/mL-plasma, while stool data is provided in units of ng/5 mL-stool. E1, estrone; E2, estradiol; E3, estriol: 2OHE1, 2-hydroxyestrone; 2MeOE1, 2-methoxyestrone; 2OHE2, 2-hydroxyestradiol; 2MeOE2, 2-methoxyestradiol; 3MeOE1, 2-hydroxyestrone-3-methyl ether; 4OHE1, 4-hydroxyestrone; 4MeOE1, 4-methoxyestrone; 4MeOE2, 4-methoxyestradiol; 16aOHE1, 16α-hydroxyestrone; 17epiE3, 17-epiestriol; 16ketoE2, 16-ketoestradiol; 16epiE3, 16-epiestriol; Total, summation of all free or totalestrogens and estrogen metabolites, dependent on category.
On the Optimal Timing of Futility Interim Analyses
Creators: name: Xi, Dong
name: Gallo, Paul
name: Ohlssen, David
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: Computational Biology

description: Futility analyses provide a mechanism to stop a trial early because of low likelihood to achieve its efficacy objective. They are usually motivated by ethical and economic purposes, so that stopping a trial with poor efficacy could save patients and resources for other promising trials. There are various methods to address futility analyses in the literature but most focus on equally spaced interim looks. We consider a constrained optimization framework where the timing and the futility boundary are decided jointly to balance the risks between stopping trials which should continue, and continuing trials which should stop. The average sample size is used as a key parameter, which is evaluated under different degrees of power loss. Alternative objective functions and constraints are compared to assess the operating characteristics of the optimal futility scheme. Numerical results for single and multiple futility looks are provided. Supplementary materials for this article are available online.
Mining of Ebola virus genome for the construction of multi-epitope vaccine to combat its infection
Creators: name: Shankar, Uma
name: Jain, Neha
name: Mishra, Subodh Kumar
name: Sk, Md Fulbabu
name: Kar, Parimal
name: Kumar, Amit
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Ebola virus is the primary causative agent of viral hemorrhagic fever that is an epidemic disease and responsible for the massive premature deaths in humans. Despite knowing the molecular mechanism of its pathogenesis, to date, no commercial or FDA approved multiepitope vaccine is available against Ebola infection. The current study focuses on designing a multi-epitope subunit vaccine for Ebola using a novel immunoinformatic approach. The best predicted antigenic epitopes of Cytotoxic-T cell (CTL), Helper-T cells (HTL), and B-cell epitopes (BCL) joined by various linkers were selected for the multi-epitope vaccine designing. For the enhanced immune response, two adjuvants were also added to the construct. Further analysis showed the vaccine to be immunogenic and non-allergenic, forming a stable and energetically favorable structure. The stability of the unbound vaccine construct and vaccine/TLR4 was elucidated via atomistic molecular dynamics simulations. The binding free energy analysis (ΔGBind = −194.2 ± 0.5 kcal/mol) via the molecular mechanics Poisson-Boltzmann docking scheme revealed a strong association and thus can initiate the maximal immune response. Next, for the optimal expression of the vaccine construct, its gene construct was cloned in the pET28a + vector system. In summary, the Ebola viral proteome was screened to identify the most potential HTLs, CTLs, and BCL epitopes. Along with various linkers and adjuvants, a multi-epitope vaccine is constructed that showed a high binding affinity with the immune receptor, TLR4. Thus, the current study provides a highly immunogenic multi-epitope subunit vaccine construct that may induce humoral and cellular immune responses against the Ebola infection. Communicated by Ramaswamy H. Sarma
Models for nearly every occasion: Part III – One box decreasing emission models
Creators: name: Hewett, Paul
name: Ganser, Gary H.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: New one box “well-mixed room” decreasing emission (DE) models are introduced that allow for local exhaust or local exhaust with filtered return, as well the recirculation of a filtered (or cleaned) portion of the general room ventilation. For each control device scenario, a steady state and transient model is presented. The transient equations predict the concentration at any time t after the application of a known mass of a volatile substance to a surface, and can be used to predict the task exposure profile, the average task exposure, as well as peak and short-term exposures. The steady state equations can be used to predict the “average concentration per application” that is reached whenever the substance is repeatedly applied. Whenever the beginning and end concentrations are expected to be zero (or near zero) the steady state equations can also be used to predict the average concentration for a single task with multiple applications during the task, or even a series of such tasks. The transient equations should be used whenever these criteria cannot be met. A structured calibration procedure is proposed that utilizes a mass balance approach. Depending upon the DE model selected, one or more calibration measurements are collected. Using rearranged versions of the steady state equations, estimates of the model variables—e.g., the mass of the substance applied during each application, local exhaust capture efficiency, and the various cleaning or filtration efficiencies—can be calculated. A new procedure is proposed for estimating the emission rate constant.
On the optimal timing of futility interim analyses
Creators: name: Xi, Dong
name: Gallo, Paul
name: Ohlssen, David
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: Computational Biology

description: Futility analyses provide a mechanism to stop a trial early because of low likelihood to achieve its efficacy objective. They are usually motivated by ethical and economic purposes, so that stopping a trial with poor efficacy could save patients and resources for other promising trials. There are various methods to address futility analyses in the literature but most focus on equally-spaced interim looks. We consider a constrained optimization framework where the timing and the futility boundary are decided jointly to balance the risks between stopping trials which should continue, and continuing trials which should stop. The average sample size is used as a key parameter which is evaluated under different degrees of power loss. Alternative objective functions and constraints are compared to assess the operating characteristics of the optimal futility scheme. Numerical results for single and multiple futility looks are provided.
Additional file 1 of Protective effects of dexmedetomidine on cerebral ischemia/reperfusion injury via the microRNA-214/ROCK1/NF-κB axis
Creators: name: Liu, Wenyi
name: Shao, Cuihua
name: Zang, Chuanshan
name: Sun, Jian
name: Xu, Min
name: Wang, Yuna
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology

description: Additional file 1.
title: saint Amand
Creators: name: Centre De Recherches Historiques / Anthropologie Historique Du Long Moyen Âge
Publisher: name: EHESS (School for Advanced Studies in Social Sciences)
Year: 2019

description: Moine à l'ile d'Yeu, évangélisateur de la région de Gand, évêque de Maastricht en 647 ; attributs : un serpent à ses pieds ou dans sa main.
Models for Nearly Every Occasion: Part III - One Box Decreasing Emission Models
Creators: name: Hewett, Paul
name: Ganser, Gary H.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: New one box “well-mixed room” decreasing emission (DE) models are introduced that allow for local exhaust or local exhaust with filtered return, as well the recirculation of a filtered (or cleaned) portion of the general room ventilation. For each control device scenario, a steady state and transient model is presented. The transient equations predict the concentration at any time t after the application of a known mass of a volatile substance to a surface, and can be used to predict the task exposure profile, the average task exposure, as well as peak and short-term exposures. The steady state equations can be used to predict the “average concentration per application” that is reached whenever the substance is repeatedly applied. Whenever the beginning and end concentrations are expected to be zero (or near zero) the steady state equations can also be used to predict the average concentration for a single task with multiple applications during the task, or even a series of such tasks. The transient equations should be used whenever these criteria cannot be met. A structured calibration procedure is proposed that utilizes a mass balance approach. Depending upon the DE model selected, one or more calibration measurements are collected. Using rearranged versions of the steady state equations, estimates of the model variables - e.g., the mass of the substance applied during each application, local exhaust capture efficiency, and the various cleaning or filtration efficiencies - can be calculated. A new procedure is proposed for estimating the emission rate constant.
The perils of balance testing in experimental design: Messy analyses of clean data
Creators: name: Mutz, Diana C.
name: Pemantle, Robin
name: Pham, Philip
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Neuroscience
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology

description: Widespread concern over the credibility of published results has led to scrutiny of statistical practices. We address one aspect of this problem that stems from the use of balance tests in conjunction with experimental data. When random assignment is botched, due either to mistakes in implementation or differential attrition, balance tests can be an important tool in determining whether to treat the data as observational versus experimental. Unfortunately the use of balance tests has become commonplace in analyses of “clean” data, that is, data for which random assignment can be stipulated. Here, we show that balance tests can destroy the basis on which scientific conclusions are formed, and can lead to erroneous and even fraudulent conclusions. We conclude by advocating that scientists and journal editors resist the use of balance tests in all analyses of clean data.
Identifying Latent Structures in Restricted Latent Class Models
Creators: name: Gongjun Xu
name: Zhuoran Shang
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: This article focuses on a family of restricted latent structure models with wide applications in psychological and educational assessment, where the model parameters are restricted via a latent structure matrix to reflect prespecified assumptions on the latent attributes. Such a latent matrix is often provided by experts and assumed to be correct upon construction, yet it may be subjective and misspecified. Recognizing this problem, researchers have been developing methods to estimate the matrix from data. However, the fundamental issue of the identifiability of the latent structure matrix has not been addressed until now. The first goal of this article is to establish identifiability conditions that ensure the estimability of the structure matrix. With the theoretical development, the second part of the article proposes a likelihood-based method to estimate the latent structure from the data. Simulation studies show that the proposed method outperforms the existing approaches. We further illustrate the method through a dataset in educational assessment. Supplementary materials for this article are available online.
Additional file 1 of Understanding changing demand for police during the coronavirus pandemic
Creators: name: Solymosi, Reka
name: Ashby, Matthew
name: Kennar, Nadia
name: Kim, Eon
name: Byrom, Karen
name: McMillan, Alexander
name: Liebelt, Phoebe
Publisher: name: figshare
Year: 2025
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplementary material 1.
Synthetic method to access fluorinated 2-benzylpyridines by using Negishi coupling reaction
Creators: name: Pothireddy, Mohanreddy
name: Bhukta, Swadhapriya
name: Babu, P. Vijaya
name: Thirupathi, Barla
name: Dandela, Rambabu
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: 2-Benzylpyridines scaffolds have been found in various drugs, bioactive natural products, and medicinally important compounds. This manuscript comprises the synthesis of various fluorinated analogs of 2-benzylpyridine compounds by using a Negishi coupling reaction as a key reaction.
Additional file 2 of The value of lncRNAs as prognostic biomarkers on clinical outcomes in osteosarcoma: a meta-analysis
Creators: name: Zhang, Wenchao
name: Ren, Xiaolei
name: Qi, Lin
name: Zhang, Chenghao
name: Tu, Chao
name: Li, Zhihong
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer
Science Policy
Hematology

description: Additional file 2. PRISMA Checklist.
Additional file 1 of Evaluation of early chemotherapy response by combining static- and dynamic [18F]FDG-PET with diffusion-weighted MRI in subcutaneous patient-derived endometrial cancer mouse models
Creators: name: Espedal, Heidi
name: Lyngstad, Jenny M.
name: Berg, Hege F.
name: Hjelmeland, Marta E.
name: Fasmer, Kristine E.
name: Krakstad, Camilla
name: Haldorsen, Ingfrid S.
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Plant Biology

description: Supplementary Material 1
Weighted False Discovery Rate Control in Large-Scale Multiple Testing
Creators: name: Basu, Pallavi
name: T. Tony Cai
name: Kiranmoy Das
name: Wenguang Sun
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: The use of weights provides an effective strategy to incorporate prior domain knowledge in large-scale inference. This article studies weighted multiple testing in a decision-theoretical framework. We develop oracle and data-driven procedures that aim to maximize the expected number of true positives subject to a constraint on the weighted false discovery rate. The asymptotic validity and optimality of the proposed methods are established. The results demonstrate that incorporating informative domain knowledge enhances the interpretability of results and precision of inference. Simulation studies show that the proposed method controls the error rate at the nominal level, and the gain in power over existing methods is substantial in many settings. An application to a genome-wide association study is discussed. Supplementary materials for this article are available online.
Mizoroki–Heck coupling reaction on the surface of sepiolite clay-supported Pd/Cu nanoalloy
Creators: name: Aryanasab, Fezzeh
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Well distributed Pd/Cu bimetallic nanoalloy supported on acid-modified sepiolite (ASEP) was prepared via a solvothermal process. The resulting system, Pd/Cu@ASEP, was characterized using spectroscopic data such as FT-IR, XRD, TEM and ICP-AES. The morphology characterization revealed that the crystalline bimetallic particles were dispersed on ASEP as nanoalloys with diameters ranged from 25 to 30 nm. This system was successfully used for ligand-free Mizoroki-Heck coupling in the presence of air, under mild conditions. This method has advantages compared to other systems, such as short reaction times, high yields, facile catalyst and easy separation and reusability of the catalyst. The catalyst was compatible with a variety of aryl and heteraryl iodides, which provides favorable products with good to high yields. Aryl and heteraryl bromides could also be activated for the Mizoroki-Heck reaction using Pd/Cu@ASEP catalyst, with good to moderate yields.
Exposure to benzene in a pooled analysis of petroleum industry case-control studies
Creators: name: D. C. Glass
name: A. R. Schnatter
name: G. Tang
name: T. W. Armstrong
name: L. Rushton
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Cases of lymphohematopoietic cancer from three petroleum industry cohorts, matched to controls from the respective cohort, were pooled into single study. Average benzene exposure was quantitatively estimated in ppm for each job based on measured data from the relevant country, adjusted for the specific time period, site and job exposure characteristics and the certainty of the exposure estimate scored. The probability of dermal exposure and of peak exposure was also assessed. Before risk was examined, an exposure estimate comparison and rationalisation exercise was performed across the studies to ensure accuracy and consistency of approach. This article evaluates the final exposure estimates and their use in the risk assessments. Overall benzene exposure estimates were low: 90% of participants accumulated less than 20 ppm-years. Mean cumulative exposure was estimated as 5.15 ppm-years, mean duration was 22 years, and mean exposure intensity was 0.2 ppm. 46% of participants were allocated a peak exposure (>3 ppm at least weekly). 40% of participants had a high probability of dermal exposure (based on the relative probability of at least weekly exposure). There were differences in mean intensity of exposure, probability of peak, and/or dermal exposure associated with job category, job site, and decade of exposure. Terminal Operators handling benzene-containing products were the most highly exposed group, followed by Tanker Drivers carrying gasoline. Exposures were higher around 1940–1950 and lower in more recent decades. Overall confidence in the exposure estimates was highest for recently held jobs and for white-collar jobs. We used sensitivity analyses, which included and excluded case-sets on the basis of exposure certainty scores, to inform the risk assessment. The above analyses demonstrated that the different patterns of exposure across the three studies are largely attributable to differences in jobs, site types, and time frames rather than study. This provides reassurance that the previous rationalisation of exposures achieved inter-study consistency and that the data could be confidently pooled.
title: Cadernos de Pedagogia Social, n. Especial (2015): Hospitalidade, educação e turismo
title: Hospitalidade, educação e turismo
titleType: AlternativeTitle
Creators: name: Cadernos De Pedagogia Social
Publisher: name: Cadernos de Pedagogia Social
Year: 2015

description: Nota de apresentação...5-6 Os novos parâmetros antropológicos da ética da hospitalidade...7-16 Hospitalidade e subjetividade – identidades tecidas na contingência...17-24 Dom – Sistema de Relações entre Pessoas...25-34 O papel da dádiva no teatro da economia – o significado antropológico do presente...35-51 Pedagogia da hospitalidade: da formação à actuação profissional em turismo...52-72 Do ensino à aprendizagem: o desafio da sala de aula pela visão da hospitalidade...73-89 Comunidades: geração espontânea ou esforço conjunto?...90-98 Héstia & Hermes – pesquisa e reflexões sobre o simbólico e a hospitalidade...99-117 Acolhida e hospitalidade na cidade: o caso do centro pastoral do migrante em São Paulo...118-135 Hospitalidade e franciscanismo no Brasil: turismo voluntário na sede da Província Franciscana de Imaculada Conceição, São Paulo...136-161 A hospitalidade na perspetiva da cidade contemporânea...162-177
Additional file 1 of Energy delivery guided by indirect calorimetry in critically ill patients: a systematic review and meta-analysis
Creators: name: Duan, Jing-Yi
name: Zheng, Wen-He
name: Zhou, Hua
name: Xu, Yuan
name: Huang, Hui-Bin
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1. Search Strategy.
Utility of 3-chloro-3-(4,9-dimethoxy-5-oxo-5H-furo[3,2-g]chromen-6-yl)prop-2-enal for construction of novel heterocyclic systems: aynthesis, characterization, antimicrobial and anticancer evaluation
Creators: name: Ibrahim, Magdy A.
name: Al-Harbi, Sami A.
name: Allehyani, Esam S.
name: Alqurashi, Esam A.
name: Alqarni, Ali O.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: 3-Chloro-3-(4,9-dimethoxy-5-oxo-5H-furo[3,2-g]chromen-6-yl)prop-2-enal (2) was utilized as a synthetic intermediate for construction of a variety of heterocyclic system linked furo[3,2-g]chromene (khellin) moiety. Reaction of compound 2 with some heterocyclic amines produced the Schiff bases 5 and 6. Treatment of compound 2 with a diversity of 1,2-, 1,3- and 1,4-binucleophilic reagents afforded a diversity of furo[3,2-g]chromenes bearing pyrazoles, pyridines, pyrimidine, pyrazolopyridine, triazolo[4,3-a]pyrimidine, pyrimido[1,2-a]benzimidazole, pyrido[1,2-a] benzimidazole, pyrido[2,3-d]pyrimidine, pyrazolo[3,4-b]pyridine, benzodiazepine, benzoxazepine and benzothiazepine. The prepared compounds were screened for their antimicrobial and anticancer activities demonstrating variable inhibitory effect. Analytical and spectral data were used to verify the structures of the newly prepared compounds.
Murine mesenchymal cells that express elevated levels of the CDK inhibitor p16(Ink4a) in vivo are not necessarily senescent
Creators: name: Frescas, David
name: Hall, Brandon M.
name: Evguenia Strom
name: Virtuoso, Lauren P.
name: Mahima Gupta
name: Gleiberman, Anatoli S.
name: Rydkina, Elena
name: Balan, Vitaly
name: Vujcic, Slavoljub
name: Chernova, Olga B.
name: Gudkov, Andrei V.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Age-related health decline has been attributed to the accumulation of senescent cells recognized in vivo by p16(Ink4a) expression. The pharmacological elimination of p16(Ink4a)-positive cells from the tissues of mice was shown to extend a healthy lifespan. Here, we describe a population of mesenchymal cells isolated from mice that are highly p16(INK4a)-positive are proficient in proliferation but lack other properties of cellular senescence. These data, along with earlier reports on p16(Ink4a)-positive macrophages, indicate that p16(Ink4a)-positive and senescent cell populations only partially intersect, therefore, extending the list of potential cellular targets for anti- aging therapies.
Synthesis of 8-Methyltetrahydroquinoline derivatives functionalized at C-2: a one-pot tandem approach
Creators: name: Guo, Zhifo
name: Hu, Feng
name: Lei, Xiangyang
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: A new synthetic method, which achieves regiospecific functionalization of 8-methylquinoline derivatives at C-2 and subsequent selective hydrogenation of the pyridine ring in a one-pot tandem process, has been reported. With this method, a total of thirteen new 8-methyltetrahydroquinoline derivatives with an amide side chain at C-2 were synthesized in moderate yields. The scope of substrates was investigated, and the reaction mechanism was studied and proposed.
Additional file 1 of Moderate ethanol exposure disrupts energy homeostasis between central and peripheral system in APP/PS1 mice
Creators: name: Kang, Shinwoo
name: Lee, Jeyeon
name: Min, Paul H.
name: Choi, Doo-Sup
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Mental Health
subject: Computational Biology

description: Supplementary Material 1
Preparation and studies of new aza[7]helicene carboxylic acid
Creators: name: Rajan, Blessy
name: Chaudhari, Twinkal M.
name: Bedekar, Ashutosh V.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: A new aza[7]helicene carboxylic acid was synthesized from carbazole in few simple steps. The helical carboxylic acid was characterized by spectroscopic techniques and its photophysical properties were evaluated. The structural parameters were compared with the theoretical values obtained from computational analysis. The molecular recognition of the helical isomers with chiral bases was examined by NMR analysis.
Modified Wilcoxon–Mann–Whitney Test and Power Against Strong Null
Creators: name: Youyi Fong
name: Huang, Ying
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The Wilcoxon–Mann–Whitney (WMW) test is a popular rank-based two-sample testing procedure for the strong null hypothesis that the two samples come from the same distribution. A modified WMW test, the Fligner–Policello (FP) test, has been proposed for comparing the medians of two populations. A fact that may be under-appreciated among some practitioners is that the FP test can also be used to test the strong null like the WMW. In this article, we compare the power of the WMW and FP tests for testing the strong null. Our results show that neither test is uniformly better than the other and that there can be substantial differences in power between the two choices. We propose a new, modified WMW test that combines the WMW and FP tests. Monte Carlo studies show that the combined test has good power compared to either the WMW and FP test. We provide a fast implementation of the proposed test in an open-source software. Supplementary materials for this article are available online.
Microwave-assisted solvent-free tandem cross-metathesis/intramolecular isomerization-cyclization reaction for the synthesis of N-substituted pyrroles: It’s computational analysis
Creators: name: Khan, Arif
name: Siddique, Asher M.
name: Shaikh, Majeed
name: Khan, Imran A.
name: Shafi, Syed
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: The microwave-assisted solvent-free reaction has been developed for the rapid synthesis of different pyrrole derivatives using cross-metathesis (CM) between N-allylamines and α, β-unsaturated carbonyl compounds with moderate to good yields. This method is solvent free, facile, rapid, and high yielding reaction for the synthesis N-substituted pyrrole derivatives. The effect of microwave irradiation versus classical thermal conditions is demonstrated through a series of comparative cross-metathesis reactions. In the present eco-friendly approach, the combination of solvent-free conditions and microwave irradiations leads to a substantial reduction in reaction times with improved yields. The computational analysis revealed that the microwave irradiation conditions favored the interconversion of ruthenacyclobutane (RuG to RuH) approximately 10-fold more than the conventional heating. Exclusive formation of pyrrole ring system (cyclization- aromatization cascade reaction) over piperazinone (aza-michael product) has been explained through DFT calculations.
Modified Wilcoxon-Mann-Whitney Test and Power against Strong Null
Creators: name: Youyi Fong
name: Huang, Ying
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: The Wilcoxon-Mann-Whitney (WMW) test is a popular rank-based two-sample testing procedure for the strong null hypothesis that the two samples come from the same distribution. A modified WMW test, the Fligner-Policello (FP) test, has been proposed for comparing the medians of two populations. A fact that may be under-appreciated among some practitioners is that the FP test can also be used to test the strong null like the WMW. In this paper we compare the power of the WMW and FP tests for testing the strong null. Our results show that neither test is uniformly better than the other and that there can be substantial differences in power between the two choices. We propose a new, modified WMW test that combines the WMW and FP tests. Monte Carlo studies show that the combined test has good power compared to either the WMW and FP test. We provide a fast implementation of the proposed test in an open-source software. Supplementary materials are available online.