cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Secondary metabolites from a peanut-associated fungus Aspergillus niger IMBC-NMTP01 with cytotoxic, anti-inflammatory, and antimicrobial activities
Creators: name: Quang, Tran Hong
name: Phong, Nguyen Viet
name: Le Ngoc Anh
name: Hanh, Tran Thi Hong
name: Cuong, Nguyen Xuan
name: Ngan, Nguyen Thi Thanh
name: Trung, Nguyen Quang
name: Nam, Nguyen Hoai
name: Van Minh, Chau
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Chemical investigation of a peanut-associated fungal strain Aspergillus niger IMBC-NMTP01 resulted in isolation and identification of 14 secondary metabolites, including two new, epi-aspergillusol (1) and aspernigin (3), and 12 known compounds: pyrophen (2), 2-(hydroxyimino)-3-(4-hydroxyphenyl)propanoic acid (4), aspergillusol A (5), rubrofusarin B (6), nigerasperone A (7), fonsecin (8), TMC-256C1 (9), pyranonigrin A (10), orlandin (11), nigerasperone C (12), asperpyrone A (13), and 5-(hydroxymethyl)-2-furancarboxylic acid (14). Compounds 9, 12-14 showed cytotoxicity toward all six human cancer cell lines, including HepG2, KB, HL-60, MCF-7, SK-Mel2, and LNCaP, with IC50 values ranging from 8.4 to 84.5 µM, compounds 3-5 were cytotoxic against five cancer cell lines except HepG2, whereas 1 exhibited cytotoxicity toward HepG2, KB, and MCF-7 cells. All of the compounds, except 2 and 13, inhibited NO overproduction in LPS-induced RAW264.7 cells. In addition, all of the compounds displayed antimicrobial effects against Enterococcus faecalis, whereas 13 compounds, except 10, significantly inhibited the growth of the yeast Candida albicans.
Brief an Johann II Bernoulli
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1777

description: Servières hat Bernoulli via Iselin zwei von ihm verfasste physikalische Schriften überreichen lassen (Observation sur le Thermomètre, Mémoire sur les extrêmes). Er bittet Johann II Bernoulli um sein Urteil. Die übersandten Exemplare möge er unter anderen Schweizer Physikern vereteilen. Servières hofft bald in die Schweiz zu kommen und Bernoulli persönlich kennenzulernen. Servières signiert als "officier dans Orléans Cavalerie".
description: von de Servières
description: Am Briefende von der Hand Servières: "Mr. Jean Bernoulli à Bâle." Dagegen von der Hand Johann III Bernoullis: "de Servières an Daniel Bernoulli". Da der vorliegende Brief auf einen nicht erhaltenen Brief von Johann II Bernoulli antwortet, der sich seinerseits auf den Brief Servières von 1777.03.31 bezieht, ist der Adressat des ersten Briefes von 1777.03.31 der gleiche wie der des vorliegenden Briefes, also Johann II Bernoulli.
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Datenimport aus LIDOS / Bernoulli (2004-07-02)
Inhalt
Creators: name: Redaktion, Die
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 2 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Acetylcholinesterase inhibitory activity from Amaryllis belladonna growing in Chile: enzymatic and molecular docking studies
Creators: name: Mella, Mónica
name: Moraga-Nicolás, Felipe
name: Machuca, Juan
name: Quiroz, Andrés
name: Mutis, Ana
name: Becerra, José
name: Astudillo, Álvaro
name: Hormazábal, Emilio
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 60506 Virology

description: Alkaloid profiles from Amaryllis belladonna plants collected in Chile were examined by GC-MS to assess their inhibitory activity on acetylcholinesterase (AChE) using in vitro and in silico methodologies. The alkaloid extract was roughly separated by column chromatography on silica gel. AChE inhibitory activities from extracts and purified alkaloids were tested by the Ellman method and a molecular docking study was performed to assess the interaction between AChE and purified alkaloids. Sixteen alkaloids were found from hexane and chloroform extracts, and three were isolated and identified as buphanidrine, acetylcaranine and lycorine. Chloroform extract showed the greatest AChE inhibitory activity with IC50 value 8.89 µg/mL, whereas buphanidrine exhibited the highest inhibitory activity, with IC50 value 17.56 µg/mL. Inhibition kinetics showed that buphanidrine acts as a mixed inhibitor and molecular docking supports this inhibition mechanism. Overall, our study supports the potential use of A. belladonna as an alkaloid source with AChE inhibitory activity.
The effect of electrode surface topography on the structure and differential capacitance of the electric double layer capacitor
Creators: name: Cao, Liulei
Publisher: name: University of Utah
Year: 2012
Subjects: Capacitor
Differential capacitance
Electric double layer
Surface topography

description: Molecular dynamics simulations were conducted to study the structure and differential capacitance of the electric double layer capacitor by varying electrode topography. Studying the dependence of structure and differential capacitance (DC) on electrode potential is a central point of electric double layer (EDL) models, from the early Gouy-Chapman approximation to the more recent Kornyshev formulation or Lamperski treatment. Although the influence on DC of temperature, density, polarisability and dispersion interactions of room  temperature ionic liquid (RTIL) electrolyte is becoming more understood, the effect of electrode topography on DC remains unclear and perhaps controversial.  Moreover, the variability of DC results for poorly prepared polycrystalline electrodes may indicate a strong dependence of EDL structure and DC on the  topography of electrode surface.  In this work, we employ molecular dynamics simulations to prove that the crystallographic orientation and the surface roughness of electrode could intensely alter the shape of DC curve as a function of electrode potential,  especially near the potential of zero charge (PZC). Specifically, we simulated a RTIL electrolyte, consisting of 1-ethyl-3-methyl imidazolium (EMIM+), bisfluorosulfonyl imide (FSI-), and Li+ (in a molar ratio of 24:31:7), in contact with two types of graphite electrodes: one is graphite with atomically flat basal plane and the other is graphite with edge orientation.  This work demonstrates that the capacitor with atomically flat basal plan graphite generates a camel-shaped DC curve; while, the capacitor with edge  orientation graphite engenders a bell-shaped DC curve. Furthermore, the capacitor with edge orientation graphite displays a significantly larger DC (almost double) than the capacitor with atomically flat basal plane graphite near PZC. Additionally, these findings coincide with the results of numerous recent experiments. Thus, we conclude that the crystallographic orientation and surface roughness will modify the EDL structure and hence, vary the DC curve of the EDLC.
Brief an Johann II Bernoulli
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1777
Subjects: Cotte, Louis1740-1815
Lalande, Joseph Jérôme Le Français de1732-1807

description: Da Servières nicht wie geplant nach Basel kommen kann, bittet er Johann II Bernoulli, ihm sein Urteil über die zwei übersandten Texte schriftlich zukommen zu lassen. De la Lande wird diese im Journal des Savants anzeigen. Servières teilt Bernoulli das günstige Urteil des Père de Cotte darüber mit.
description: von de Servières
description: Am Briefende "Mr. Jean Bernoulli à Bâle." Von der Hand Joh. III B.s "de Servières an Johann II Bernoulli"
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Datenimport aus LIDOS / Bernoulli (2004-07-02)
Antidiabetic effect of aqueous-ethanol extract from the aerial parts of Artemisia roxburghiana
Creators: name: Kumar, Ankit
name: Aswal, Sonali
name: Chauhan, Ashutosh
name: Semwal, Ruchi Badoni
name: Singh, Randhir
name: Andola, Harish Chandra
name: Joshi, Sunil Kumar
name: Semwal, Deepak Kumar
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 60506 Virology

description: Artemisia roxburghiana is used for the management of diabetes mellitus in the Indian subcontinent. The present work aimed to validate the traditional claim of the plant in diabetes mellitus. In vitro studies were conducted using α-glucosidase and α-amylase assays whereas streptozotocin-nicotinamide-induced diabetic Wistar rats were used for in vivo study. The aqueous-ethanol extract from the aerial parts was found to exhibit α-glucosidase and α-amylase inhibitory activities with the IC50 values of 31.0 and 17.2 mg/mL, respectively when compared with acarbose (IC50 = 8.6 and 16.25 mg/mL, respectively). The extract showed a significant glucose-lowering effect in diabetic rats at the doses of 200 and 400 mg/kg in a dose-dependent manner, while acarbose (10 mg/kg) was used as a standard. The results revealed that A. roxburghiana aerial parts showed antidiabetic activity via inhibiting α-glucosidase and α-amylase enzymes. The present study also validated the ethnomedicinal claim of the plant in diabetes mellitus.
Sonnenfleckenzeichnung Nr. 23033.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 04.04.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Hormone sensitivity of particulate pineal guanylate cyclase
Creators: name: Carmack, Curtis F.
Publisher: name: University of Utah
Year: 2012
Subjects: Cyclic guanylic acid
Melatonin
Serotonin
Pineal gland

description: Guanylate cyclase was studied in vitro using crude plasma membrane fractions of bovine and rabbit pineals.  The particulate quanylate cyclase was stimulated 1.5-to 6-fold by the non-ionic detergent triton X-100.  The effects of various adrenergic agents and pineal indoles were also tested.  Serotonin, the endogenous precursor to the pineal hormone melatonin, stimulated particulate guanylate cyclase with optimal stimulation at 10-5 M.  Melatonin inhibited particulate guanylate cyclase, with a maximal inhibition of 85% at 10-3 M.  The adrenergic agents isoproterenol ( a ?-agonist) and phenylephrine (an ?-agonist) inhibited the particulate guanylate cyclase 95% and 75%, respectively.  The endogenous adrenergic neurotransmitter, norepinephrine, had no effect on pineal particulate guanylate cyclase.  Combinations of ?- and ?-agonists were effective inhibitors at concentrations that had no effect if either agent was added alone.  Stimulation of guanylate cyclase by serotonin and inhibition by melatonin imply the possibility that these two endogenous pineal indoles may play a role in feedback control of pineal cGMP  metabolism, and possible other pineal functions.
Purification of inosine monophosphate by thin layer chromatography and detection of inosine monophosphate within cellular messenger RNA
Creators: name: Paul, Michael Sean
Publisher: name: University of Utah
Year: 2012
Subjects: Inosine
Thin layer chromatogrpahy

description: This dissertation describes the development and use of novel thin layer chromatography (TLC) purification methods that allowed for the specific and sensitive detection of inosine monophosphate (IMP) within cellular mRNA. Radioactive 5' nucleoside monophosphate (5' NMP) mixtures were prepared from mRNA, and then spiked with nonradioactive 5' IMP. This nonradioactive 5' IMP served as a marker for the migration of radioactive 5' IMP and allowed for the conclusive identification of radioactive 5' IMP derived from mRNA. Three consecutive rounds of TLC purified 5' IMP away from the more abundant ribonucleotides found within RNA (adenosine monophosphate, guanosine monophosphate, cytidine monophosphate, and uridine monophosphate), as well as other minor modified nucleotides found within RNA. These purification methods allowed for the detection of 1 to 5 parts IMP per 1 million parts NMPs (1-5 ppm).  Radioactive 5' NMPs were prepared from polyadenylated RNA isolated from a number of different rat tissues. TLC analyses of these 5' NMPs showed that 5' IMP was most abundant in brain mRNA, and the tissue specific abundance of 5' IMP directly correlated with the expression of genes encoding adenosine deaminases that act on RNA (ADARs). Quantitation of this endogenous IMP provided the first estimate of the amount of inosine in cellular mRNA.  It was also demonstrated that in polyoma virus infected cells, IMP levels in cellular RNA increased with viral titer. Polyoma early (sense) and late (antisense) RNAs are thought to form double-stranded RNAs (dsRNAs) within the cell nucleus and undergo significant modification by ADARs. Cells were infected with polyoma virus and nuclear and cytoplasmic RNA was subsequently isolated at various hours postinfection. TLC analyses showed that 5' IMP was present in nucleotides derived from nuclear RNA isolated at the late stage of polyoma infection but 5' IMP was not present in nucleotides derived from nuclear RNA isolated at the early stage of polyoma infection. These results suggest that stable dsRNA duplexes exist within the nucleus during the late stage of polyoma infection and that these duplexes are modified by ADARs.
Sonnenfleckenzeichnung Nr. 23021.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.03.1969, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Genotyping by High-Resolution Amplicon Melting
Creators: name: Seipp, Michael Todd
Publisher: name: University of Utah
Year: 2012
Subjects: Genomics
Gene Amplification

description: Genotyping by high-resolution amplicon melting is a simple method using  only PCR primers and double-stranded DNA binding dyes. Heterozygous genotypes  are easily assigned based on derivative melting curve shape and width. Homozygous  genotypes are assigned based on Tm differences that are usually 1 °C but can be less.  One potential drawback to genotyping by amplicon melting is Tm variance that can be  caused by solution chemistry differences and thermal variability of PCR instruments.  To address the Tm variance, internal temperature standards were created using  complimentary 3'-blocked oligonucleotides which were included in each reaction.  Genotyping by amplicon melting lends itself to potential multiplexing, due to only  primers being used for detection. A thrombophilia panel, including the F5, F2, and  the MTHFR 677 and 1298 mutations, was used as a multiplex model because of the  potential additive effects of mutations at multiple loci. The first set of experiments  were done using the LightCycler 1.5 and HR-1 technologies, which performed well in  a blinded study of 109 samples. This assay was further improved by conversion to a  mutli-sample high-resolution platform combining the LightCycler and HR-1  technologies. This new process decreased hands-on manipulation as well as overall  analysis time while maintaining the same resolution.
Signal processing, human factors, and modelling to support bedside care in the intensive care unit
Creators: name: Görges, Matthias
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Graphical display
subject: Human factors
subject: Intensive care unit
subject: Nursing
subject: FOS: Health sciences
subject: Signal processing

description: Medical error causes preventable death in nearly 100,000 patients per year in the US alone. Common sources for error include medication related problems, technical equipment failure, interruptions, complicated and error-prone devices, information overload (providing too much patient data for one person to process effectively), and environmental problems like inadequate lighting or distracting ambient noise.  Intensive care units are one of the riskiest locations in a hospital, with up to 9 reported events per 100 patient days. This risk is in large contrast to anesthesia in  the operating rooms. Here much advancement in the area of patient safety has been made in the past, dropping the average risk for anesthesia related death to less than 1 in 200,000 anesthetics-an improvement by a factor of 20 in the past 30 years. Improvements in technology and other innovations contributing to this success now need to be adapted for and implemented in the intensive care unit setting.  Nurses are increasingly regarded as key decision makers within the healthcare team, as they outnumber physicians 4:1. Reducing nurses' workload and improving  medical decision making by providing decision support tools can have a significant impact in reducing the chances of medical errors.  This dissertation consists of four manuscripts: 1) a review of previous medical display evaluations, providing insight into solutions that have worked in the past;  2) a study on reducing false alarms and increasing the usefulness of the remaining alarms by introducing alarm delays and detecting alarm context;, such as suctioning  automatically silencing ventilator alarms; 3) a study of simplifying the frequent but complicated task of titrating vasoactive medications by providing a titration support  tool that predicts blood pressure changes 5 minutes into the future; and 4) a study on supporting the triage of unfamiliar patients by introducing a far-view display that  incorporates information from previously disparate devices and presents trend and alarm information at one easy to scan and interpret location.
Relationship between chronic anxiety and perceptions of illness behavior in latency-aged children
Creators: name: Ferrari, Patricia
Publisher: name: University of Utah
Year: 2012
Subjects: Illness Behavior

description: A primary mental health coal is helping children to develop self-esteem and the ability to cop with stress and anxiety.  A preventive approach could foster an awareness of children at risk for chronic anxiety and in need of assistance, particularly in situations perceived to be unusually stressful.  This study was conducted to examine the relationship between the dimensions of manifest anxiety and latency-aged children's perceptions of their own illness behaviors.  On the assumption that the intensity of the anxiety is proportionate to the meaning the individual ascribes to a given situation, it was proposed that subjective perceptions of illness might be more threatening to children who are chronically anxious than to those who are not, and would be less able to cope effectively.  Three hypotheses were developed based on a review of the literature.  The first stated that the more anxious the children were, the more likely they would be to perceive themselves displaying either very many of very few illness behaviors.  The second hypothesis stated that the less anxious latency-aged children were, the more likely they would be to perceive themselves displaying a moderate amount of illness behaviors.  The third hypothesis stated that there would be no significant difference between the perceived illness behaviors of healthy children and those of children with a significant history of illness.  Fifty-four children age eight to 11 were administered a questionnaire containing a manifest anxiety scale which consisted of physical, worry and fear dimensions, and an illness behavior scale which contained emotionality, acceptance and communication dimensions.  Through the use of Pearson Product-Monment Correlation Coefficients (r), the dimensions of each of these scales were correlated to determine whether or not significant relationships existed.  There was no significant relationship between the total illness behavior score and the total manifest anxiety score.  Therefore, neither the first nor second hypotheses was supported.  However, a scattergram was used to illustrate that children with the highest anxiety scores had high illness behavior scores while children with lower manifest anxiety scores had moderately-ranged illness behavior scores.  This indicates that children with moderately high anxiety scores were more likely to perceive themselves displaying many illness behaviors, while children who had low anxiety scores were apt to perceive themselves displaying a moderate amount of illness behaviors.  A t-test for independent measures demonstrated no significant difference between the responses of healthy children with a recent hasty of illness.  Therefore, the third hypothesis was supported.  An additional finding of the study was that of all the aspects of illness behavior, emotionality was most related to manifest anxiety and was significantly correlated with physical aspects, worry aspects, and total manifest anxiety score.
Antifungal sesquiterpenes with post-harvest anthracnose control effect on bananas from the fungus Fusarium lateritium
Creators: name: Zhu, Junjie
name: Xiong, Ping
name: Li, Ziyang
name: Li, Jiazhong
name: Lin, Longsheng
name: Fu, Xing
name: Huang, Yuxuan
name: Xiong, Yahong
name: Li, Chunyuan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology

description: To search for antifungal leads, the metabolites of an insect-derived fungus Fusarium lateritium ZMT01 were investigated, providing five sesquiterpenes (1–5), including new molecules microsphaeropsisins D and E (1 and 2). The evaluated antifungal activities in vitro which are higher than the positive control triadimefon include: 1 and 2 towards Fusarium oxysporum (MICs 50, 25 mg L−1; triadimefon 100 mg L−1); 1, 2, 4 and 5 towards Penicillium italicum (MICs 25, 12.5, 25, 25; triadimefon 50 mg L−1), 1, 2 and 4 towards Colletotrichum musae (MICs 25, 12.5, 25; triadimefon 80 mg L−1), 2 and 4 towards Fusarium graminearum (MICs 100, 100; triadimefon 150 mg L−1). The bioassay in vivo displayed that the banana anthracnose control effect of 2 (100 mg L−1) was also higher than that of triadimefon (Inhibition ratios 27.5 ± 2.5%, 55.3 ± 1.4%, 52.1 ± 1.3% for 2, 22.5 ± 2.1%, 47.2 ± 2.0%, 36.6 ± 2.2% for triadimefon at 4 d, 8 d and 12 d, respectively).
Idealized large-eddy simulation sensitivity studies of sea and lake breezes
Creators: name: Crosman, Erik T.
Publisher: name: University of Utah
Year: 2012
Subjects: Lake breeze
Large-eddy simulation
Numerical modeling
Sea breeze
Thermally-driven circulation
Atmospheric circulation

description: Numerical studies of sea and lake breezes are reviewed and gaps in our current understanding of these thermally-driven circulations are discussed. A numerical sensitivity study is conducted using large-eddy simulations to determine the dependence of sea- and lake-breeze speed and length scales to variations in the land-surface sensible heat flux, offshore background wind, initial atmospheric stability, and lake diameter. This study is the first to test the dependence of sea- and lake-breeze characteristics to variations in these geophysical variables using a three-dimensional large-eddy simulation capable of explicitly resolving boundary-layer turbulence and vertical motion near the sea-breeze front.  This study provides new understanding on the sensitivity of sea and lake breezes to variations in the land-surface sensible heat flux, opposing background wind, and lake diameter as well as the complex interactions that occur among these geophysical variables. For the first time, the daytime life cycle of sea and lake breezes in the presence of variations in these variables is simulated, in contrast to many earlier studies that focused primarily on the mature midafternoon sea-breeze circulation. Significant spatial variability in the intensity and vertical structure of lake and sea breezes is noted in the large-eddy simulations. The critical value of an opposing wind at which a sea or lake breeze is destroyed by synoptic-scale pressure gradients is approximately 20% lower in this study than that documented in earlier numerical studies. The depth of sea and lake breezes has also been found to be highly sensitive to the magnitude of the opposing background wind. Finally, the results of this study show that lake breezes for small and medium-sized lakes evolve much differently than sea breezes during the afternoon due to a limited quantity of cool air over the lake.
Terpestacin, a toxin produced by Phoma exigua var. heteromorpha, the causal agent of a severe foliar disease of oleander (Nerium oleander L.)
Creators: name: Masi, Marco
name: Zonno, Maria Chiara
name: Boari, Angela
name: Vurro, Maurizio
name: Evidente, Antonio
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Since 1987, several cytochalasins were isolated from Phoma exigua var. heteromorpha, the causal agent of foliar blight disease of oleander (Nerium oleander L.), and chemically and biologically characterised. During the purification process of a large-scale production of cytochalasins A and B, necessary to continue the study on their anticancer activity, a metabolite having a different carbon skeleton compared to that of cytochalasans, was isolated. It was identified as terpestacin, a well-known toxic fungal stestertepenoid, isolated for the first time from P. exigua var. heteromorpha, by spectroscopic investigation (essentially 1D and 2D 1H and 13C-NMR and ESI MS) and optical methods in comparison with the literature data. Terpestacin and some its derivatives (including a natural one, fusaproliferin) were prepared and tested for their biological activity. Terpestacin and fusaproliferin had some inhibitory effects on seed germination of Phelipanche ramosa, whereas none of the compounds caused phytotoxic effects on weed leaves.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.04.1969, erstellt von Gisèle Evrard-Kesteloot, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Effiziente Datenminimierung im Gebäude- und Quartierssektor
Creators: name: Rupp, Valentin
name: Heumüller, Julie
name: von Grafenstein, Maximilian
Publisher: name: Zenodo
Year: 2022
Subjects: Data Protection
Data Governance
Datenschutz
Gebäude
Quartier
Privacy by Design
Smart Home
Energiewende
Energiewendebauen

description: Beim Einsatz digitaler Anwendungen im Gebäude- und Quartierssektor lassen in diesem Rahmen verarbeitete Datensätze zu Raumklima, Energieverbrauch und sonstigen gebäudebezogenen Daten häufig Rückschlüsse auf das Verhalten von Einzelpersonen oder Personengruppen zu. Beziehen sich diese Daten auf eine identifizierte oder identifizierbare Person, findet das nationale bzw. europäische Datenschutzrecht Anwendung und mit ihm die gesamte Bandbreite rechtlicher Verpflichtungen des Verantwortlichen. Ziel des Datenschutzrechts ist es dabei, die Betroffenen vor Risiken zu schützen, die durch die Datenverarbeitung verursacht werden und ihnen damit grundsätzlich die Entscheidung über das Maß und dem Umgang mit diesen Risiken zu gewähren. Da das Datenschutzrecht dies an den sehr unbestimmten Begriff des personenbezogenen Datums knüpft, ist bei vielen Anwendungen dabei nicht von vornherein absehbar, welche tatsächlichen und rechtlichen Folgen im konkreten Fall an eine Verarbeitung der Daten geknüpft sind. Die vorliegende Visualisierung soll daher der Erläuterung dienen, wie anhand einer Berücksichtigung von Risiken für Betroffene der Personenbezug von Daten ermittelt und durch den Einsatz technisch-organisatorischer Maßnahmen möglichst weitgehend minimiert werden kann. Auf diese Weise wird einerseits der rechtlichen Verpflichtung eines effektiven Schutzes von Betroffenen Rechnung getragen. Andererseits können digitale Anwendungen mit einer höheren Rechts- und damit Planungssicherheit betrieben werden.
Cnemida Kirby 1827
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Cnemida

description: CNEMIDA Kirby, 1827
Cnemida Kirby 1827: 146
Synopsis. Jameson 1996
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 132, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 23004.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.02.1969, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Notizen und Auszüge rechtswissenschaftlichen Inhalts
Creators: name: Faesch, Remigius
name: Pfister, Conrad
Publisher: name: [s.n.]
Year: 1600

description: Remigius Faesch
description: Öffentliche Bibliothek der Universität Basel
description: Lateinisch
description: Aus der Handschrift O I 7 des Museums des Remigius Faesch, welcher die Blätter lose beilagen, herausgenommen und gesondert gebunden (1938).
description: Verzeichnung=Description=Inventaire Dez. 2009 Titel, Entstehungszeit, Sprache, Vorbesitzer, Signatur nach: Binz, ungedruckte Beschreibung
description: Verzeichnung=Description=Inventaire März 2012 Minimalaufnahme nach: Binz (1938)
description: Verzeichnung=Description=Inventaire Juni 2019 HAN-Katalogisierungsregeln Normalaufnahme auf der Basis von Binz (1938) Flury
description: Verzeichnung=Description=Inventaire September 2019 revidiert Müller/Flury
description: Erschliessungsniveau Normalniveau
Sonnenfleckenzeichnung Nr. 23001.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.02.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Enhanced nilpotent representations of a cyclic quiver
Creators: name: Johnson, Casey Patrick
Publisher: name: University of Utah
Year: 2012
Subjects: Colored partition
Combinatorics
Enhanced orbit
Geometry
Nilpotent
Quiver representation

description: We de ne a set of \enhanced" nilpotent quiver representations that generalizes both the enhanced nilpotent cone and the colored nilpotent cone. This set admits an action by an associated algebraic group K with  nitely many orbits. We de ne a combinatorial set that parametrizes the set of orbits under this action and we derive a purely combinatorial formula for the dimension of an orbit. Finally, we present a conjectural combinatorial description of the closure order.
Baudenkmale gefährdet – Baudenkmale gerettet
Creators: name: Oelwein, Cornelia
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 3 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
The role of viral regulatory protein ICP0 in herpes simplex type 1 keratitis
Creators: name: Shahnazaryan, David
Publisher: name: Royal College of Surgeons in Ireland
Year: 2020
Subjects: subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences

description: Herpes simplex keratitis (HSK) is the commonest cause of infectious blindness in the developed world. It is caused by herpes simplex virus type 1 (HSV‐1) and is characterised by recurrent episodes of infection and immune‐mediated corneal inflammation that lead to significant loss of vision. Following transmission of HSV‐1 the virus is initially suspended in the tear film, where it encounters a multi‐pronged defence comprising enzymes, complement, immunoglobulins and crucially, a range of anti‐viral and pro‐inflammatory cytokines. HSV‐1, however, is able to overcome innate immune responses, to establish lifelong latency and to reactivate throughout susceptible individual’s lifetime with the potential of causing irreversible damage to the sight. The crucial roles of viral regulatory protein ICP0 in the pathogenesis of HSV‐1 infection is well established. ICP0 is important for the virus’s ability to cause a productive infection, to establish a latent state and to successfully reactivate. However, the molecular mechanisms behind these processes are largely unknown. The aim of this study was to investigate the interactions between ICP0 and key elements of type I IFN pathway and to identify possible targets that contribute to viral survival. Our Luciferase studies have demonstrated the ability of ICP0 to inhibit type I IFN activity downstream of TLRs 3, 4 and 7 which are known to be involved in host antiviral defences. Further co‐transfection experiments have identified IRF7, a crucial driver of IFN‐ as a potential target for ICP0. IRF7 stability experiment has confirmed that IRF7 is targeted by ICP0 for degradation in a dose dependent fashion. This finding is another step towards better understanding of the pathogenesis of herpes simplex keratitis (HSK) and may become a potential therapeutic target for HSK.
Inszenierung der Antike. Klassizistische Dekoration der Ismaninger Schloss-Säle
Creators: name: Oelwein, Cornelia
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Ausstellung: Inszenierung der Antike. Klassizistische Dekoration der Ismaninger Schloss-Säle. Ausstellung im Schlossmuseum Ismaning bis 29. Januar 2017.
description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 3 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Maueranker und Stier. Plesse/ Plessen. Tausend Jahre eines norddeutschen Adelsgeschlechtes
Creators: name: Küntzel, Thomas
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Rezension zu: Maueranker und Stier. Plesse/ Plessen. Tausend Jahre eines norddeutschen Adelsgeschlechtes. Herausgegeben durch Christian von Plessen. Schwerin: Thomas Helms Verlag, 2015. 1076 Seiten, zahlreiche, teils farbige Abb. und Karten. ISBN 978-3-944033-03-7.
description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 3 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Adjusting to living in a nursing home: toward a nursing intervention model.
Creators: name: Brooke, Virginia M.
Publisher: name: University of Utah
Year: 2012
Subjects: Gerontology
Older People
Phychological Adaptation

description: The purpose of this study was to describe phases in adjustment of older adults living in a nursing home during the first 6-8 months; describe residents' perceptions of the nursing home environment; and develop a nursing model to help older adults adjust to living in a nursing home. This was a longitudinal participant-observation clinical study. The nurse-researcher assumed the role of care provider while collecting data over 10-months. The sample consisted of 41 newly admitted adults (mean age 84.5), 11 males, 31 females, and 4 married couples, followed in one 155 bed intermediate care nursing home. Data were also gathered on mental and functional status, level of depression, characteristics of the environment, family visits, perceived state of health, voluntary nature of the move, falls, daily medications ordered, and tranquilizers taken weekly. Phases describing adaptation to living in a nursing home were divided into four major concepts. Newly admitted residents were highly upset for about 4 to 6 weeks and developed behavioral patterns of turning-in toward themselves. This was called 'disorganization.' Residents in this phase were challenged to deal with losses of self, relationships and accustomed space. Residents then appeared to begin problem-solving, and directing some of their own care, 'reorganization,' and were challenged to find meaning in the experience. During the 'relationship-building' phase, about month 3, residents established supportive ties with family, staff and other residents. Married couples offered each other support, but faced changes such as loss of physical and mental capacity that challenged their relationship. About the third or fourth month, residents seemed to 'fit-in' to the nursing home environment, 'stabilization,' being motivated to become established while maintaining self-definition. Residents returned to disorganization during any emotional or physical setback. The perceived voluntary (70% of the sample) or involuntary (30% of the sample) nature of the move was a key to understanding various responses to institutionalization. Nursing care should focus on the residents' cognitive, physical and emotional perceptions of reality and vary according to which phase residents are experiencing. The goal of nursing care during disorganization is helping the resident grieve the losses and learn about a new environment; during reorganization is supporting problem-solving efforts, helping find meaning in the experience of living in a nursing home, and supporting attempts at managing care; during relationship building supporting intimacy, mediating conflict, and supporting through loss; and during stabilization supporting integrity and acknowledging decline.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.02.1969, erstellt am Kandilli Observatorium Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Kandilli Rasathanesi, Çengelköy (Istanbul). Instrument: Refraktor Teleskop (Öffnung 200 mm, f = 3070 mm, projiziertes Sonnenbild D = 25 cm).
Instrumentennachweis gemäss Kandilli Observatory Istanbul, Report from Solar Institute, in: Solar Physics, 1968, Vol. 3, Issue 3, pp.491-492, DOI: https://doi.org/10.1007/BF00171622
Cnemida lacerata
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Cnemida
Cnemida lacerata

description: Cnemida lacerata (Germar, 1824)
Rutela lacerata Germar 1824: 119 (Brazil)
Distribution. French Guiana: Jameson 1996: 295; Soula 2010a: 55 (?); Brûlé et al. 2011a: 192; RMNH. Brazil: Germar 1824: 119 (as Rutela lacerata); Ohaus 1934: 119; Blackwelder 1944: 239; Machatschke 1972: 52; Jameson 1996: 295. Venezuela: Jameson 1996: 295. Other: Jameson 1996: 295 (Paraguay).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 132, DOI: 10.5281/zenodo.3678492
Food for Thought: Investigating Communication Strategies to Counteract Moral Disengagement Regarding Meat Consumption
Creators: name: Buttlar, Benjamin
name: Rothe, Alisa
name: Kleinert, Simon
name: Hahn, Lena
name: Walther, Eva
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Eating less meat would benefit environmental sustainability, human health, and animal welfare. Providing information about this, however, does often not lead people to adopt according beliefs, attitudes or behaviors. In fact, dietary changes are often prevented by dissonance reduction (i.e. moral disengagement) if information elicits a conflict regarding meat. In the present investigation we thus aimed to address moral disengagement via a communication strategy that consisted of two stages: In Stage I, we presented information by showing distressing scenes from animal agriculture. In Stage II, we then counteracted moral disengagement in a dialog. Two studies indicate that, following the dialog, people’s evaluations of meat changed and their willingness to eat meat decreased; this seemed to result from lowered moral disengagement. By providing an empirically tested communication strategy for addressing moral disengagement on the exemplary conflict regarding meat, we hope to inspire research and interventions that intend to communicate (environmental) issues.
The Contagion Effect of Neighboring Foreclosures on Own Foreclosures
Creators: name: Lawley, Chad
name: Towe, Charles
Publisher: name: Digital Repository at the University of Maryland
Year: 2010
Subjects: Housing and Community Development
Maryland
foreclosures
housing market
home foreclosure

description: In this paper, we examine a highly localized contagion effect of foreclosures and find strong evidence that social interactions influence the decision to foreclose. We utilize a hazard model and a unique spatially explicit dataset documenting parcel level residential foreclosures in Maryland for the years 2006 through 2009. We combine these data with tax and assessment data, loan data, Census, and unemployment data. These data allow us to control for important factors influencing the likelihood of foreclosure within a given community, including the prevalence of subprime loans and the distribution of socioeconomic characteristics. Additionally, we use the tax data to construct variables describing individual homes, surrounding homes, and community. These variables include structural characteristics of houses, their price history, and length of ownership.
Sonnenfleckenzeichnung Nr. 23022.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.03.1969, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel