cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Targeted Bottom–Up Mass Spectrometry Approach for the Relative Quantification of Post-Translational Modification of Bovine κ-Casein during Milk Fermentation
Creators: name: Sagu, Sorel Tchewonpi
name: Rawel, Harshadrai M.
name: Rohn, Sascha
Publisher: name: Technische Universität Berlin
Year: 2022
Subjects: subject: 540 Chemie und zugeordnete Wissenschaften
subject: bovine milk
subject: fermentation
subject: κ-casein
subject: post-translational modifications
subject: glycosylation, phosphorylation
subject: mass spectrometry

description: κ-casein (κ-CN) is one of the key components in bovine milk, playing a unique role in the structuration of casein micelles. It contains in its chemical structure up to sixteen amino acid residues (mainly serine and threonine) susceptible to modifications, including glycosylation and phosphorylation, which may further be formed during milk processing. In this study, changes in post-translational modification (PTM) of κ-CN during bovine milk fermentation were investigated. One-to-five-day fermented milk samples were produced. A traditional bottom–up proteomics approach was used to establish a multiple-reaction monitoring (MRM) method for relative quantification of κ-CN PTM. Endoproteinase Glu-C was found to efficiently digest the κ-CN molecule. The developed LC-MS method was validated by performing assessments of linearity, precision, repeatability, reproducibility, limit of detection (LOD), and limit of quantification (LOQ). Among the yielded peptides, four of them containing serine and threonine residues were identified and the unmodified as well as the modified variants of each of them were relatively quantified. These peptides were (1) IPTINTIASGEPTSTTE [140, 158], (2) STVATLE [162, 168], (3) DSPE [169, 172], and (4) INTVQVTSTAV [180, 190]. Distribution analysis between unmodified and modified peptides revealed that over 50% of κ-CN was found in one of its modified forms in milk. The fermentation process further significantly altered the composition between unmodified/modified κ-CN, with glycoslaytion being predominant compared to phosphorylation (p < 0.01). Further method development towards α and β-CN fractions and their PTM behavior would be an asset to better understand the changes undergone by milk proteins and the micellar structure during fermentation.
Determining genetic risk for posttraumatic chronic pain and related neuropsychiatric disorders using polygenic risk scores.
Creators: name: Lobo, Jarred
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Twin and family studies have reported a significant contribution of genetic factors to onset of chronic pain and related psychiatric disorders. Technological advancements now allow for the systematic testing of genetic variants across the genome for association with traits to better understand the cumulative effect of different alleles. This project aimed to determine whether a polygenic model can be used to predict genetic risk for posttraumatic chronic pain and posttraumatic stress symptom development. Polygenic risk scores were generated using GWAS discovery datasets and the target dataset consisting of European individuals between 18 and 65 years of age who presented to the ED within 24 hours of a motor vehicle collision. Phenotypes tested included pain intensity (scale from 0-10), depression (CESD scale), and PTSD (IESR scale). PRSice, polygenic risk score software, was used to calculate, evaluate, and plot the results of the analyses. The variance explained by the PRS model for moderate posttraumatic chronic pain (4-10 on pain scale) ranged from 1-3% using polygenic risk scores for back pain. As the polygenic risk score increased, the odds ratio for year 1 moderate pain generally increased. Similar results were observed when testing other GWAS discovery datasets and phenotypes. The polygenic risk scores quantify the cumulative effect of genetic variants that play a significant role in the development of posttraumatic chronic pain and related symptoms. Future research may combine these polygenic risk scores with nongenetic risk factors to predict individual susceptibility. Health care providers may use polygenic risk scores as well as nongenetic risk factors to evaluate a patient’s risk of chronic pain in order to create an individualized treatment plan.
Greek Palatals
Creators: name: Colby, Evan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: This project was an attempt to determine whether or not all of the palatal consonants in Greek share the same place of articulation by using acoustic data. The conclusion was that the all of the consonants have roughly the same effect on the formants of surrounding vowels and thus probably have roughly the same place of articulation.
Shadows of CPR black holes and tests of the Kerr metric
Creators: name: Ghasemi-Nodehi, M.
name: Li, Zilong
name: Bambi, Cosimo
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We study the shadow of the Cardoso-Pani-Rico (CPR) black hole for different values of the black hole spin $a_*$, the deformation parameters $ε_3^t$ and $ε_3^r$, and the viewing angle $i$. We find that the main impact of the deformation parameter $ε_3^t$ is the change of the size of the shadow, while the deformation parameter $ε_3^r$ affects the shape of its boundary. In general, it is impossible to test the Kerr metric, because the shadow of a Kerr black hole can be reproduced quite well by a black hole with non-vanishing $ε_3^t$ or $ε_3^r$. Deviations from the Kerr geometry could be constrained in the presence of high quality data and in the favorable case of a black hole with high values of $a_*$ and $i$. However, the shadows of some black holes with non-vanishing $ε_3^r$ present peculiar features and the possible detection of these shadows could unambiguously distinguish these objects from the standard Kerr black holes of general relativity.
description: 10 pages, 7 figures. v2: refereed version with minor changes
ASSESSMENT OF HIV/AIDS-RELATED MORTALITY AMONG PRIMARY AND SECONDARY SCHOOL TEACHERS IN ADDIS ABABA (1998-2003) USING VERBAL AUTOPSY
Creators: name: Abebe Asmelash
Publisher: name: Zenodo
Year: 2004

description: Acquired Immunodeficiency Syndrome (AIDS) has become a number one killer disease in Africa. The problem is believed to be so grave among government employees in general and teachers in particular; however, there are little hard data that substantiate the severity of the problem in these population groups . This cross-sectional study was aimed at assessing HIV/AIDS related mortality among primary and secondary school teachers. A total of 88 schools (66 primary and 22 secondary) were randomly selected for the survey and 193 deaths were identified. Complete data were obtained for 169 cases using verbal autopsy questionnaire. Verbal autopsies were reviewed by three physicians to determine the underlining cause of death. EPI-info version 6 and SPSS version 10 statistical packages were used to enter and analyze data. Proportions and rates were calculated to define the problem.
Sub-Analysis to Differential Labor Market Impact of the Covid-19 Pandemic Response on Workers with Young Children
Creators: name: Barkowski, Scott
name: McLaughlin, Joanne
name: Dai, Yinlin
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Public Economics
subject: Health Economics
subject: Labor Economics
subject: Economics
subject: Social and Behavioral Sciences
subject: Childcare
subject: COVID-19
subject: labor market
subject: pandemic response

description: This registration specifies our plans for a sub-analysis for our project titled “Differential Labor Market Impact of the COVID-19 Pandemic Response on Workers with Young Children,” which was previously registered on OSF on May 13th, 2020 (available here: https://osf.io/vh952). The sub-analysis is of new questions about labor market responses to the COVID-19 pandemic that were first asked of respondents in the May 2020 version of the Current Population Survey (CPS) basic monthly survey. Data for respondent answers to these questions have not yet been made available to the public.
Inattentional Blindness: Baseline Study
Creators: name: Williams, Lauren
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Cognitive Psychology
subject: Cognition and Perception
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: The purpose of this study is to establish a baseline detection rate for the incidental abnormalities that were frequently missed when radiologists were asked to focus their attention on lung cancer nodules in previous research (https://osf.io/je8tm/).
Graphical functions in parametric space
Creators: name: Golz, Marcel
name: Panzer, Erik
name: Schnetz, Oliver
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Graphical functions are positive functions on the punctured complex plane $\mathbb{C}\setminus\{0,1\}$ which arise in quantum field theory. We generalize a parametric integral representation for graphical functions due to Lam, Lebrun and Nakanishi, which implies the real analyticity of graphical functions. Moreover we prove a formula that relates graphical functions of planar dual graphs.
description: v2: extended introduction, minor changes in notation and correction of misprints
Strategic Confrontation: Examining the Utility of Low Stakes Prodding as a Strategy for Confronting Sexism
Creators: name: Good, Jessica
name: Woodzicka, Julie
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: The present research examines an indirect confrontation strategy we term low stakes prodding. We first establish the use of this strategy in a real-time sexist situation (Pilot study, N=59), then test whether this indirect type of confrontation is considered to be an effective strategy for reducing sexism (Study 1, N=138), and finally investigate whether low stakes prodding is deliberately used to avoid work-related costs (Study 2, N= 129). Study 1 demonstrated that the majority of respondents perceived low stakes prodding as confrontation, but viewed it as less effective when it was delayed. Study 2 showed that low stakes prodding was seen as a somewhat deliberate confrontation strategy that contributes to positive interpersonal interactions. The manuscript based on the three studies (Pilot, Study 1, Study 2) contained in this registration was accepted for publication in The Journal of Social Psychology on September 17, 2020.
Second harmonic generation and pulse shaping in positively and negatively spatially dispersive nanowaveguides: comparative analysis
Creators: name: Popov, Alexander K.
name: Myslivets, Sergey A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Comparative analysis of second harmonic generation in ordinary and backward-wave settings is presented. Extraordinary properties of frequency doubling nonlinear optical reflectivity and pulse shaping through phase matching of ordinary and backward electromagnetic waves in the nanowaveguides with mixed negative/positive spatial dispersion is demonstrated with numerical simulations.
description: 10 pages, 5 figures
ORCID Popups: Starting Small to Disseminate at Large
Creators: name: Argabright, Lynnee
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019
Subjects: Academic libraries
Special events--Planning
Electronic publishing

description: For this Spring 2019 semester, UNC librarians will be setting up a series of “ORCID popups” following departmental faculty meetings. We will show them what ORCID is and help willing faculty register for an ORCID iD live. Creating an ORCID account may be simple but is not well communicated to faculty—only 206 faculty have UNC ORCID iDs. An ORCID iD distinguishes researchers despite name confusions and shortcuts various research workflows; it also allows librarians and deans to track impact metrics of UNC research output. These popups are an attempt to build awareness at UNC of a tool supporting faculty research activity in an open, public manner, thereby building networks and encouraging knowledge dissemination.
Two-Fluid Theory for Spin Superfluidity in Magnetic Insulators
Creators: name: Flebus, B.
name: Bender, S. A.
name: Tserkovnyak, Y.
name: Duine, R. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate coupled spin and heat transport in easy-plane magnetic insulators. These materials display a continuous phase transition between normal and condensate states that is controlled by an external magnetic field. Using hydrodynamic equations supplemented by Gross-Pitaevski phenomenology and magnetoelectric circuit theory, we derive a two-fluid model to describe the dynamics of thermal and condensed magnons, and the appropriate boundary conditions in a hybrid normal-metal|magnetic-insulator|normal-metal heterostructure. We discuss how the emergent spin superfluidity can be experimentally probed via a spin Seebeck effect measurement.
Glocalização, Sustentabilidade, Desenvolvimento e Criatividade
Creators: name: EMMENDOERFER, MAGNUS
Publisher: name: Zenodo
Year: 2023
Subjects: Glocalization
Development
SGD
Sustainability
Creativity

description: Aula aberta, apresentada no formato online, na disciplina PGTP115 - Políticas Globais e Relações locais, Criatividade e Desigualdades: Apontamentos para o Desenvolvimento Sustentável do Turismo e do Patrimônio, criada e ofertada pela primeira vez no curso de mestrado em Turismo e Patrimônio do PPGTURPATRI - Universidade de Ouro Preto (UFOP), no âmbito da Cátedra UNESCO em Economia Criativa e Políticas Públicas, com sede na Universidade Federal de Viçosa (UFV), período 2023.1. Disciplina de 60h/a - compartilha com os professores da UFOP: Kerley dos Santos Alves e Marcos Eduardo de Carvalho Gonçalves Knupp Ementa: Diretrizes políticas globais e relações políticas locais; Glocalização e Sustentabilidade. Teorias de Desenvolvimento pela Criatividade, Implicações, efeitos, impactos e criticidades do desenvolvimento no Sul Global.
description: A gravação da aula está disponível em: https://drive.google.com/file/d/1bV9GeFm1rRH5FOkFT5FPSrrf2yvw9mpC/view?usp=sharing
A mini systematic review of help-seeking behaviours for self-harm among young people aged between 11 to 25 years old.
Creators: name: Kirkpatrick, Alison
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: A mini-systematic review of the literature of help-seeking behaviours for self-harm among young people aged 11 and 25 years old, with no restrictions on location. Submitted in fulfilment of MSc project.
A Radical Approach to Polycycles Using Carboxylic Acids
Creators: name: Hunter Gadwill
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description:        Over the nine weeks of the fellowship, two principle reagents were synthesized for application in the reaction intended with a multi-step synthesis and 24 test reactions were conducted to screen for the desired product and optimize intermediate product yield. After proton and fluorine NMR spectra were collected and analyzed to identify the compounds in the reaction mixture, GCMS was conducted during the data analysis process to verify that no desired product was formed. Although the anticipated product was not formed, a useful intermediate is formed in significant quantities, which may be used to subsequently access a known reaction that yields the desired product. The intermediate (formed from a radical transition state that readily reacts with more xanthate material) was identified through NMR spectroscopic analysis that confirmed a suspected byproduct mechanistic pathway. In the future, I would like to use known chemistry to transform the intermediate into the desired product. This multi-step synthesis would still avoid the use of transition metal catalysts, and indirectly achieve the desired reaction.
Pseudo-Chemotactic Drifts of Artificial Microswimmers
Creators: name: Ghosh, Pulak K.
name: Li, Yunyun
name: Marchesoni, Fabio
name: Nori, Franco
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We numerically investigate the motion of active artificial microswimmers diffusing in a fuel concentration gradient. We observe that, in the steady state, their probability density accumulates in the low-concentration regions, whereas a tagged swimmer drifts with velocity depending in modulus and orientation on how the concentration gradient affects the self-propulsion mechanism. Under most experimentally accessible conditions, the particle drifts toward the high-concentration regions (pseudo-chemotactic drift). A correct interpretation of experimental data must account for such an "anti-Fickian" behavior.
description: 6 pages
Vagal system function and emotion processing in MIDUS Refresher
Creators: name: Quinlan, Laurel
name: Finley, Anna
name: Mumford, Jeanette
name: Schaefer, Stacey
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences
subject: Autonomic nervous system
subject: Emotion processing
subject: Emotion reaction
subject: Emotion recovery
subject: Eyeblink
subject: Facial EMG
subject: Heart rate variability
subject: HRV
subject: Midlife in the United States
subject: MIDUS
subject: Startle

description: The Midlife in the United States (MIDUS) Refresher study provides an excellent opportunity to examine the relationship between HRV and emotion regulation across a diverse sample of United States adults. We hope to expand upon previous findings in the MIDUS II sample by examining the relationship between resting baseline measures of HRV and psychophysiological indicators of emotional reactivity and recovery within an emotional picture viewing paradigm. Indicators of emotional reactivity and recovery will be quantified by the magnitude of startle eyeblink reflex (EBR) during multiple timepoints.
Characterizing MARK2-Dependent Regulation of CBP-Mediated Acetylation in Alzheimer’s Disease
Creators: name: Tabassum, Zarin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Tau is a neuronal microtubule-binding protein that forms characteristic neurofibrillary tangles (NFT), upon hyperphosphorylation, hyperacetylation, and aggregation, which are hallmark biomarkers for Alzheimer’s disease (AD). The pathophysiological conversion of tau still remains unclear, but the regulation and synergy of tau’s post-translational modifications (PTMs) by certain enzymes can be monitored. This study investigates the interactions between two enzymes involved in regulating tau’s PTMs: the microtubule affinity-regulating kinase (MARK2) and the acetyltransferase CREB-binding protein (CBP). We performed a series of biochemical analyses, which uncovered that CBP-mediated acetylation was increased in the absence of MARK2, indicating a possible negative feedback loop, in which MARK2 is phosphorylating and thereby inhibiting CBP. Further investigation of the protein-protein interactions revealed increased acetylation of an inactive MARK2 mutant compared to wild-type MARK2 in the presence of CBP. This finding supports the idea that active MARK2 may be involved in decreasing CBP-mediated acetylation. Although the exact mechanism of this interaction and its role in tau dysfunction have yet to be determined, we have uncovered a new signaling pathway in which two enzymes may regulate each other.
Application and Parameterization of a 1D Multifluid Population Balance Model for Gas-Liquid  Processes
Creators: name: Breit, Ferdinand
name: Weibel, Christian
name: von Harbou, Erik
Publisher: name: Zenodo
Year: 2024
Subjects: gas liquid interaction,
reactive multi-phase flow
Sensitivity and parameter analysis
PBE
Multifluid
Population Balance Model
Bubble column

description: Reactive gas-liquid processes in bubble column reactors exhibit complex behavior influenced by various factors, including gas consumption, bubble rising velocity, coalescence, and breakage. Scaling up these reactors from laboratory to production scale requires a thorough understanding of the interdependency of these processes and their dependence on reactor dimensions. While multiphase computational fluid dynamics approaches can provide valuable information, their computational cost remains a challenge, hindering comprehensive parameter studies in the early-stage process development. To address this, a 1D multifluid population balance model (MPB) is proposed, offering lower computational costs and deep insight due to the consideration of the population balance. However, due to model simplifications, calibration with experimental data is necessary. In this study, a broad experimental database is established, encompassing over 600 experiments in a laboratory bubble column. A calibration procedure is developed based on the data, resulting in a predictive MPB that accurately describes the behavior of the bubbly flow across various compositions, operating points, and bubble column heights. These findings are a crucial step towards a robust and reliable simulation-based scale-up of gas-liquid reactors.
description: Ferdinand Breit was the presenter.
Interactions of $B_{c}$ Meson in Relativistic Heavy-Ion Collisions
Creators: name: Irfan, Shaheen
name: Akram, Faisal
name: Masud, Bilal
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We calculate the absorbtion cross-sections of $B_{c}$ mesons by $π$ and $ρ$ mesons including anomalous processes using an effective hadronic Lagrangian. The enhancement of Bc production is expected due to QGP formation in heavy-ion experiments. However it is also expected that the production rate of Bc meson can be affected due to the interaction with comovers. These processes are relevant for experiments at RHIC. Thermal average cross-sections of $B_{c}$ are evaluated with form factor when a cut off parameter in it is 1 and 2 GeV. Using these thermal average cross-sections in the kinetic equation we investigate the time evolution of $B_{c}$ mesons due to dissociation in the hadronic matter formed at RHIC.
description: This paper was presented in 7th International Meeting on Particles and Fields ,1st - 4th April 2015 at Center for High Energy Physics, Punjab University, Lahore, Pakistan
Proprietà intellettuale [monopoli] e dati nel settore della produzione agricola
Creators: name: Caso, Roberto
Publisher: name: Zenodo
Year: 2023
Subjects: Proprietà intellettuale
Monopolio
Smart farming
Agricoltura di precisione

description: La relazione è finalizzata a discutere il problema della concentrazione di potere di controllo ed elaborazione dei dati nelle mani di grandi imprese commerciali (big tech) che forniscono ai produttori agricoli servizi di agricoltura di precisione e smart farming. Il problema della concentrazione di potere di controllo ed elaborazione dei dati è già stato analizzato in chiave interdisciplinare in molti altri settori della c.d. era dei dati: ad es., nel settore della ricerca scientifica dove si delinea una disparità di potere tra imprese di analisi dei dati e istituzioni accademico-scientifiche (università e centri di ricerca). La relazione è divisa in tre parti. Nella prima parte si riassume il dibattito sul capitalismo dei monopoli intellettuali e della sorveglianza. Tali monopoli traggono la loro forza dalla proprietà intellettuale e dalla pseudo-proprietà intellettuale (forme anomale di esclusiva che si basano, ad esempio, su contratto e misure tecnologiche di protezione). Nella seconda parte si descrive la peculiarità delle dinamiche di potere nel settore agricolo con riferimento ad agricoltura di precisione e smart farming. La normativa europea in materia di dati sembra essere insufficiente a risolvere il problema della disparità di potere, in quanto non scioglie alcuni nodi di politica del diritto che attengono al rapporto tra settore pubblico (stato) e settore privato (imprese) e riguardano la regolazione della proprietà intellettuale e della pseudo-proprietà intellettuale. Nella terza parte, muovendo da un’analogia con il settore della ricerca scientifica, si propongono alcune raccomandazioni di politica del diritto su infrastrutture tecnologiche e regolazione della proprietà intellettuale.
description: https://webmagazine.unitn.it/evento/cjm/115481/verso-unagricoltura-data-intensive-prospettive-e-criticit-della-disciplina
BEYOND DIGITAL DETERMINISM AND TOWARD THE 4.0 JOINT, PARTICIPATORY, AGILE ORGANIZATION
Creators: name: SHABA, EMANUELA
Publisher: name: Universit� degli Studi di Milano
Year: 2021

description: The analysis of three companies that have jointly considered the technical and the social systems while designing and implementing the new digital technologies shows how and to what extent the Socio-Technical Systems (STS) principles are nowadays adopted, thereby indicating the possibility that the STS theory can (re) become central in both theory and managerial practices. Thereby we propose an ?actualized? sociotechnical design approach, capable in aligning an organization to the rapid and radical change that come along with the digitalization and indicate that the application of STS-informed design methods, such as Agile and Design Thinking, oriented more to action and intervention, mirroring the actual act of designing in a dynamic way, but also offer organizations the opportunity to embrace a broader stakeholder base.
Thoughts on Publishing Survey - how can we improve scientific publishing?
Creators: name: Pimentel, Ricky
Publisher: name: UNC
Year: 2019

description: There are various pathways for scientists to share their work, but the most important method is the peer-reviewed manuscript. Lately, publishing in academic journals has become more competitive and time consuming, but fraudulent work and errors still occur in many journals. We propose an alternative publishing model that fits within our current model and could improve access to readers and support more efficient review. The goal of thoughts on publishing survey (TOPS) is to measure satisfaction levels of the current publishing model, propose an alternative publishing model, obtain feedback on the new model, and learn more about quality scientific articles and peer review. With this feedback, we highlight some areas that may improve publishing, for the reader, writer, and reviewer. We also assess the acceptance of an alternative model and identify ways that it could be implemented. Whatever scientific publishing may look like in the future, consumers and producers of these works should keep the goal in mind: “How can we make the peer-reviewed manuscript fit our workload and budget, and improve its value and reach to foster scientific advancement?”
Thermo-Mechanical Analysis of Railway Wheel – Rail Rolling/Sliding contact
Creators: name: Rebira Wirtu
Publisher: name: Zenodo
Year: 2017

description: Thermal damage caused by frictional heat of rolling-sliding contact is one of the most important failure forms of wheel and rail. The coupled mechanical–thermal behavior of wheel and rail materials under rolling contact is studied to determine the temperature rise due to the frictional heat. The wheel–rail frictional rolling contact problem is solved using the both hertz three– dimensional finite element (FE) method. The FE model considers the wheel tread–rail top contact with partial-slip and converts the frictional energy into the heat as an attempt to estimate the temperature rise. The assembly of wheel-rail geometry is created by CATIA V5R20 software. The finite element program ANSYS workbench is used to model the couple of thermos-mechanical rolling –sliding contact analysis and used to simulate the loading and boundary conditions of the wheel-rail rolling/sliding contact. When the couple of mechanical – thermal (maximum pressure and different heat flux) applied on the wheel – rail rolling/ sliding contact, it generates a maximum amount of heat and stress between rail and wheel. This cause plastic strain development and reduction of stress fatigue life for the increased value of loads that resulted from slippage as can note from analysis and simulation results. Rolling contact stress states and material response of wheel – rail under four traction coefficient and the same varying of sliding velocity were investigated. 3D coupled thermomechanical FE model were developed to analyze the temperature rise due to high applied load at contact and the thermal influence on residual stress-strain, wear and rail life
A Fredholm alternative for quasilinear elliptic equations with right hand side measure
Creators: name: Colturato, Michele
name: Degiovanni, Marco
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35J66

description: We consider a quasilinear elliptic equation, with right hand side measure, which does not satisfy the usual coercivity assumption. We prove an existence result in the line of the Fredholm alternative. For this purpose we develop a variant of degree theory suited to this setting.
description: 32 pages. With respect to the previous version, the proof of Theorem 1.1 has been divided in the new Lemma 4.1 and the remaining part
Quantum K-theoretic geometric Satake
Creators: name: Cautis, Sabin
name: Kamnitzer, Joel
Publisher: name: arXiv
Year: 2015
Subjects: subject: Representation Theory (math.RT)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: The geometric Satake correspondence gives an equivalence of categories between the representations of a semisimple group $ G $ and the spherical perverse sheaves on the affine Grassmannian $Gr$ of its Langlands dual group. Bezrukavnikov-Finkelberg developed a derived version of this equivalence which relates the derived category of $ G^\vee$-equivariant constructible sheaves on $ Gr $ with the category of $G$-equivariant ${\mathcal O}(\mathfrak g)$-modules. In this paper, we develop a K-theoretic version of the derived geometric Satake which involves the quantum group $ U_q \mathfrak g $. We define a convolution category $ KConv(Gr) $ whose morphism spaces are given by the $ G^\vee \times \mathbb C^\times $-equivariant algebraic K-theory of certain fibre products. We conjecture that $KConv(Gr)$ is equivalent to a full subcategory of the category of $ U_q \mathfrak g $-equivariant $ \mathcal O_q(G) $-modules. We prove this conjecture when $G = SL_n$. A key tool in our proof is the $SL_n$ spider, which is a combinatorial description of the category of $U_q \mathfrak{sl}_n$ representations. By applying horizontal trace, we show that the annular $SL_n$ spider describes the category of $ U_q \mathfrak{sl}_n $-equivariant $ \mathcal O_q(SL_n) $-modules. Then we use quantum loop algebras to relate the annular $SL_n $ spider to $ KConv(Gr) $. This gives a combinatorial/diagrammatic description of both categories and proves our conjecture.
description: 58 pages
Three-year-olds’ sensitivity to appropriate motives behind a commitment failure
Creators: name: Bonalumi, Francesca
name: Siposova, Barbora
name: Christensen, Wayne
name: Michael, John
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: Commitments create obligations, but the precise scope of commitments can never fully be made explicit. For instance, we expect someone to be released from her commitment anytime this conflicts with a weightier moral consideration (Shpall, 2014). Previous research has shown that 3-year-old children not only have an understanding of the obligations entailed by commitments (Gräfenhain et al., 2009; Hamann et al., 2012), they also distinguish between instances in which a partner fails to make a contribution intentionally and instances in which she fails to do so for external reasons or out of incompetence (Kachel et al., 2018). But are children at that age also able to assess the legitimacy of reasons why agents may intentionally refrain from acting in accordance with commitments? To probe this, we manipulate the kind of reason that leads a partner to break a commitment. In the main task, three-year-old children play a game with a puppet in order to obtain rewards. In two different conditions, the game is interrupted by the partner either because (a) the partner has been allured to play another tempting game; or (b) the partner consoles another agent in distress. We predict that three-year-old children differentiate between these two cases, protesting normatively against defection and being less willing to wait when the joint activity is interrupted because of another temping game.
RICERCA DI MICROMETASTASI LINFONODALI IN PAZIENTI CON NSCLC. ANALISI MOLECOLARE DEL CEA MRNA MEDIANTE REAL TIME RT-PCR E VALUTAZIONE DEL SUO VALORE PROGNOSTICO
Creators: name: MARZORATI, ANTONELLA
Publisher: name: Universit� degli Studi di Milano
Year: 2012

description: Malignant tumors of epithelial are the most frequent category of malignancy, and are a major cause of death in developed countries. The most common diseases are those involving cancers of the respiratory system. The more aggressiveis form is represented by non-small cell carcinomas (NSCLC). The RT-PCR has greater sensitivity in identifying lymph node micrometastases, while also achieving a higher specificity if it is carried out to quantify the target of interest by Real Time PCR. Leveraging the versatility of CEA mRNA as a marker for lymph node micrometastases, it was decided to develop a system of quantification in real-time PCR able to: obtain a high sensitivity/specificity; lead to a speeding up of diagnostic time and the detection of the disease in its early stage; allow you to customize and improve the quality of care and outcome in advanced stage. Considering separately patients histologically N0, N1 and N2 were obtained the following results: 15 of 58 histologically N0 patients were positive for the molecular investigation, obtaining a P <0.05%; 7 of 10 histologically N1 patients were positive to molecular analysis, obtaining a P <0.05%; 13 histologically N2 patients of 13 were positive to molecular analysis, showing a 100% concordance between the two diagnostic methods. The molecular analysis has allowed the restaging of 21 patients: 5 N0 patients were restaging N1, 10 N0 patients were restaging N2 and 6 N1 patients with stage N1 were restaging N2.
D3.3 Blue Cloud Demonstrator Users Handbook V1
Creators: name: Nys, Cecile
name: Maudire, Gilbert
Publisher: name: Zenodo
Year: 2020
Subjects: Aquaculture monitor
Demonstrator
Fish a matter of scales
Marine Environmental Indicators
Plankton Genomics
Zoo and Phytoplankton EOV products

description: This deliverable, D3.3 "Blue Cloud Demonstrator Users Handbook V1" is a first version of the handbook and guidelines on how to use the Virtual Research Environments (VREs) of the five demonstrators. For each demonstrator, the following information will be described: the objective, the targeted users, a summary of their provided services and the guidelines of how to use their respective VREs. As this version of the Handbook describes the β-version of the VREs, it is not fully complete and final, as the VREs are not fully finalised yet. It must be considered as an intermediate version to be used internally for integration and testing. This Handbook V1 is an ongoing and living document. It will be updated following advances of the demonstrators and their VREs. The final version V2 of this handbook will be published in M27 of the Blue-Cloud project (December 2021) and will be open to users. Intermediate versions in between now and then will be written and possibly made accessible online, following progress of demonstrators and their VREs, deploying functionalities, achieving results, etc.
Interventions for management of children/youth with cerebral palsy at risk of osteoporosis: a second systematic review update and meta-analysis using GRADE
Creators: name: Bohn, Emma
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Diseases
subject: Medicine and Health Sciences
subject: Musculoskeletal Diseases
subject: Bone mineral density
subject: Cerebral palsy
subject: Meta-analysis
subject: Osteoporosis
subject: Systematic review

description: A systematic review and meta-analysis of management options for children and young people with cerebral palsy and at risk of osteoporosis.
Evolution of the Neoarchaean Kola alkaline granites, northeastern Fennoscandian Shield: insights from SHRIMP-II titanite and zircon U-Pb isotope and rare earth elements data
Creators: name: Arzamastsev, Andrei A.
name: Belyatsky, Boris V.
name: Rodionov, Nikolai V.
name: Antonov, Anton V.
name: Lepekhina, Elena N.
name: Sergeev, Sergei A.
Publisher: name: Geological Society of London
Year: 2023
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: S1: Data tables on the whole rock composition, REE concentrations in titanite and other accessories.
Blind at First Sight: The Role of Distinctively Accurate and Positive First Impressions in Romantic Interest
Creators: name: Kerr, Lauren
name: Human, Lauren
name: Back, Mitja
name: McClure, M. Joy
name: Lydon, John
name: Tissera, Hasagani
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Personality and Social Contexts
subject: Social Psychology
subject: Cognition and Perception
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: attraction
subject: Distinctive accuracy
subject: extraversion
subject: first impressions
subject: positivity
subject: speed dating

description: Viewing others with distinctive accuracy – the degree to which personality impressions corresponds with targets’ unique characteristics – often predict positive interpersonal experiences, including liking and relationship satisfaction. Does this hold in the context of first dates, or might distinctive accuracy have negative links with romantic interest in such evaluative settings? We examined this with two speed-dating samples (N1 = 172, Ndyad = 2407; N2 = 397, Ndyad = 1849). Not surprisingly, positive impressions of potential dating partners were strongly associated with greater romantic interest. In contrast, distinctively accurate impressions were associated with significantly less romantic interest. This association was even stronger for potential partners whose personalities were less romantically appealing, specifically, those lower in extraversion. In sum, on a first date, distinctive accuracy tends to be paired with lower romantic interest. The potential implications of distinctive accuracy for romantic interest and of interest for distinctive accuracy are discussed.
Topological Phase Transition in Single Crystals of $(Cd_{1-x} Zn_x)_3 As_2$
Creators: name: Lu, Hong
name: Zhang, Xiao
name: Jia, Shuang
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Single crystals of $(Cd_{1-x} Zn_x)_3 As_2$ were synthesized from high-temperature solutions and characterized in terms of their structural and electrical properties. Based on the measurements of resistivity and Hall signals, we revealed a chemical-doping-controlled transition from a three dimensional Dirac semimetal to a semiconductor with a critical point $x_c/sim 0.38$. We observed structural transitions from a body-center tetragonal phase to a primary tetragonal phase then back to a body-center tetragonal phase in the solid solutions as well, which are irrelevant to the topological phase transition. This continuously tunable system controlled by chemical doping provides a platform for investigating the topological quantum phase transition of 3D Dirac electrons.
description: 14 pages, 8 figures, 1table
Push button reproduction attempt of a research claim from Fuhrmann, M., & Kreps, S. E., (2010), in Journal of Conflict Resolution
Creators: name: Talbert, Eli
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: International and Area Studies

description: We selected the claim that states are more likely to attack or consider attacking the nuclear programs of states with which they recently experience violent militarized conflict (Hypothesis 1) (Statement 2). This reflects the following statement from the paper's abstract: "Three factors increase the salience of the proliferation threat: (1) prior violent militarized conflict; (2) the presence of a highly autocratic proliferator; and (3) divergent foreign policy interests. The authors test these propositions using statistical analysis and a new data set on all instances when countries have struck or seriously considered striking other states’ nuclear infrastructure between 1941 and 2000" (Statement 1). The authors adopt a standard time-series cross-section data structure with the directed dyad year as the unit of analysis. Attack is a dummy variable that is coded 1 if a state attacked a proliferating country in year t and 0 otherwise. As a measure of whether states in a dyad are involved in violent militarized conflict the authors create 'violent conflict,' which is a dichotomous variable that equals 1 if they are involved in an ongoing militarized interstate dispute (MID) in year t - 1 involving the use of force. The authors use rare events logit. Table 4 displays the initial results of the multivariate statistical analysis, and Model 5 is the selected model (see Model 5 in Table 4 for details) (Statement 3). Violent conflict is statistically and negatively related to attacks (from Model 5 in Table 4, 'Violent conflict' term: estimate = 2.845; robust SE = 1.006; significant at 1 percent) (Statement 4). The focal test in the original paper is: Violent conflict is statistically and negatively related to attacks (from Model 5 in Table 4, 'Violent conflict' term: estimate = 2.845; robust SE = 1.006; significant at 1 percent)
Evolution of the Neoarchaean Kola alkaline granites, northeastern Fennoscandian Shield: insights from SHRIMP-II titanite and zircon U-Pb isotope and rare earth elements data
Creators: name: Arzamastsev, Andrei A.
name: Belyatsky, Boris V.
name: Rodionov, Nikolai V.
name: Antonov, Anton V.
name: Lepekhina, Elena N.
name: Sergeev, Sergei A.
Publisher: name: Geological Society of London
Year: 2023
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: S3: Data tables on the whole rock composition, BSE images of analysed titanite and zircon grains.
Convergent validity of a multi-modal assessment of alexithymia and its relationship with an extensive battery of social cognition
Creators: name: Rösch, Sarah
name: Puhlmann, Lara
name: Preckel, Katrin
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Psychiatry and Psychology
subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Alexithymia
subject: BVAQ
subject: Cyberball
subject: Director's Task
subject: Dominance analysis
subject: exploratory factor analysis
subject: False Belief
subject: RMET
subject: Social Cognition
subject: TAS
subject: TSIA

description: This project aims to advance our understanding of the construct alexithymia through two research goals: Firstly, identify the factors underlying multi-modally assessed alexithymia (self-report and interview). Secondly, examine the relation between the factors underlying alexithymia and an extensive battery of social cognition (comprised of the recognition of other people's affective mental states, representation of other people's cognitive mental states, visual perspective-taking, and affective distress of social rejection).
Observability of the target indicators in the 3D CMEMS MFC systems (D3.4)
Creators: name: Brasseur, P
name: Brankart, J.M.
name: Popov, M
name: Skakala, J
name: Teruzzi, A
name: Spada, S
name: Cossarini, G
name: Wakamatsu, T
name: Bertino, L
name: Sun, Y
name: Nerger, L
Publisher: name: Zenodo
Year: 2023
Subjects: SEAMLESS
CMEMS
Indicators
Horizon2020

description: SEAMLESS has the strong ambition to develop novel ensemble data assimilation systems exploitable operationally in the CMEMS MFCs, in some cases as alternative of established variational methods. The rationale is to improve the estimation of key marine ecosystem indicators. The objectives of this document are: (i) to report on the developments of ensemble assimilation methods and assimilation experiments performed in SEAMLESS, and (ii) to provide methodological guidelines to assess the observability and controllability of the target indicators across the CMEMS MFC 3D domains using common probabilistic evaluation tools.
BATC 15 Band Photometry of the Open Cluster NGC 188
Creators: name: Wang, Jiaxin
name: Ma, Jun
name: Wu, Zhenyu
name: Wang, Song
name: Zhou, Xu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: This paper presents CCD multicolour photometry for the old open cluster NGC 188. The observations were carried out as a part of the Beijing--Arizona--Taiwan--Connecticut Multicolour Sky Survey from 1995 February to 2008 March, using 15 intermediate-band filters covering 3000--10000 Å. By fitting the Padova theoretical isochrones to our data, the fundamental parameters of this cluster are derived: an age of $t=7.5\pm 0.5$ Gyr, a distant modulus of $(m-M)_0=11.17\pm0.08$, and a reddening of $E(B-V)=0.036\pm0.010$. The radial surface density profile of NGC 188 is obtained by star count. By fitting the King model, the structural parameters of NGC 188 are derived: a core radius of $R_{c}=3.80'$, a tidal radius of $R_{t}=44.78'$, and a concentration parameter of $C_{0}=\log(R_{t}/R_{c})=1.07$. Fitting the mass function to a power-law function $ϕ(m) \propto m^α$, the slopes of mass functions for different spatial regions are derived. We find that NGC 188 presents a slope break in the mass function. The break mass is $m_{\rm break}=0.885~M_{\odot}$. In the mass range above $m_{\rm break}$, the slope of the overall region is $α=-0.76$. The slope of the core region is $α=1.09$, and the slopes of the external regions are $α=-0.86$ and $α=-2.15$, respectively. In the mass range below $m_{\rm break}$, these slopes are $α=0.12$, $α=4.91$, $α=1.33$, and $α=-1.09$, respectively. The mass segregation in NGC 188 is reflected in the obvious variation of the slopes in different spatial regions of this cluster.
description: Accepted for Publication in AJ, 11 pages, 9 figures and 4 tables
Dynamical response to a stationary tidal field
Creators: name: Landry, Philippe
name: Poisson, Eric
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We demonstrate that a slowly rotating compact body subjected to a stationary tidal field undergoes a dynamical response, in which the fluid variables and the interior metric vary on the time scale of the rotation period. This dynamical response requires the tidal field to have a gravitomagnetic component generated by external mass currents; the response to a gravitoelectric tidal field is stationary. We confirm that in a calculation carried out to first order in the body's rotation, the exterior geometry bears no trace of this internal dynamics; it remains stationary in spite of the time-dependent interior.
description: 12 pages