cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Aqueous core epigallocatechin gallate PLGA nanocapsules: characterization, antibacterial activity against uropathogens, and in vivo reno-protective effect in cisplatin induced nephrotoxicity
Creators: name: Alotaibi, Badriyah
name: El-Masry, Thanaa A.
name: Elekhnawy, Engy
name: El-Kadem, Aya H.
name: Saleh, Asmaa
name: Negm, Walaa A.
name: Abdelkader, Dalia H.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine

description: Epigallocatechin-3-gallate (EGCG) was isolated from Cycas thouarsii leaves for the first time and encapsulated in aqueous core poly(lactide-co-glycolide) (PLGA) nanocapsules (NCs). This work investigates antimicrobial activity and in vivo reno-protective effects of EGCG-PLGA NCs in cisplatin-induced nephrotoxicity. A double emulsion solvent evaporation process was adopted to prepare PLGA NCs loaded with EGCG. Particle size, polydispersity index (PDI), zeta potential, percent entrapment efficiency (�), structural morphology, and in vitro release platform were all studied in vitro. The optimum formula (F2) with particle size (61.37 ± 5.90 nm), PDI (0.125 ± 0.027), zeta potential (–11.83 ± 3.22 mV), � (85.79 ± 5.89%w/w), initial burst (36.85 ± 4.79), and percent cumulative release (87.79 ± 9.84) was selected for further in vitro/in vivo studies. F2 exhibited an enhanced antimicrobial activity against uropathogens as it had lower minimum inhibitory concentration (MIC) values and a more significant impact on bacterial growth than free EGCG. Forty male adult mice were randomly allocated into five groups: control vehicle, untreated methotrexate, MTX groups treated with a daily oral dose of free EGCG, placebo PLGA NCs, and EGCG PLGA NCs (F2) for 10 days. Results showed that EGCG PLGA NCs (F2) exerted promising renoprotective effects compared to free EGCG. EGCG PLGA NCs group induced a significant decrease in kidney index, serum creatinine, kidney injury molecule-1 (KIM-1), NGAL serum levels, and pronounced inhibition of NLPR-3/caspase-1/IL/1β inflammasome pathway. It also significantly ameliorated oxidative stress and decreased NFκB, Bax expression levels. Aqueous core PLGA NCs are a promising formulation strategy that provides high polymeric protection and sustained release pattern for hydrophilic therapeutic agents.
title: Qualification et quantification des flux de la mine au lagon et de leurs impacts. Rapport scientifique final
Creators: name: Allenbach, Michel
name: Bertand, Mélanie
name: Despinoy, Marc
name: Evrard, Olivier
name: Garcin, Manuel
name: Liébault, Frédéric
name: Navratil, Oldrich
name: Recking, Alain
name: Richard, Didier
name: Rouet, Isabelle
name: Sabinot, Catherine
name: Sellier, Virginie
name: Tessier, Bernadette
name: Thinon, Isabelle
name: Touraivane, T.
name: Worliczek, Élisabeth
Publisher: name: CNRT Nickel et son environnement
Year: 2020
Subjects: subject: FOS: Earth and related environmental sciences
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: Programme Immila. (Tome Nickel et Environnement)
Construction of iron-mineralized black phosphorene nanosheet to combinate chemodynamic therapy and photothermal therapy
Creators: name: Shi, Zhaoqing
name: Tang, Jing
name: Lin, Chuchu
name: Chen, Ting
name: Zhang, Fan
name: Huang, Yuxing
name: Luan, Ping
name: Xin, Zhuo
name: Li, Qianqian
name: Mei, Lin
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Chemodynamic therapy (CDT) by triggering Fenton reaction or Fenton-like reaction to generate hazardous hydroxyl radical (•OH), is a promising strategy to selectively inhibit tumors with higher H2O2 levels and relatively acidic microenvironment. Current Fe-based Fenton nanocatalysts mostly depend on slowly releasing iron ions from Fe or Fe oxide-based nanoparticles, which leads to a limited rate of Fenton reaction. Herein, we employed black phosphorene nanosheets (BPNS), a biocompatible and biodegradable photothermal material, to develop iron-mineralized black phosphorene nanosheet (BPFe) by in situ deposition method for chemodynamic and photothermal combination cancer therapy. This study demonstrated that the BPFe could selectively increase cytotoxic ·OH in tumor cells whereas having no influence on normal cells. The IC50 of BPFe for tested tumor cells was about 3–6 μg/mL, which was at least one order of magnitude lower than previous Fe-based Fenton nanocatalysts. The low H2O2 level in normal mammalian cells guaranteed the rare cytotoxicity of BPFe. Moreover, the combination of photothermal therapy (PTT) with CDT based on BPFe was proved to kill tumors more potently with spatiotemporal accuracy, which exhibited excellent anti-tumor effects in xenografted MCF-7 tumor mice models.
Multifunctional icariin and tanshinone IIA co-delivery liposomes with potential application for Alzheimer’s disease
Creators: name: Wang, Jiao
name: Kong, Liang
name: Guo, Rui-Bo
name: He, Si-Yu
name: Liu, Xin-Ze
name: Zhang, Lu
name: Liu, Yang
name: Yu, Yang
name: Li, Xue-Tao
name: Cheng, Lan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Cell Biology
Molecular Biology
Neuroscience
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Mental Health

description: The blood–brain barrier (BBB) is a protective barrier for brain safety, but it is also a major obstacle to the delivery of drugs to the cerebral parenchyma such as the hippocampus, hindering the treatment of central nervous system diseases such as Alzheimer’s disease (AD). In this work, an anti-AD brain-targeted nanodrug delivery system by co-loading icariin (ICA) and tanshinone IIA (TSIIA) into Aniopep-2-modified long-circulating (Ang2-ICA/TSIIA) liposomes was developed. Low-density lipoprotein receptor-related protein-1 (LRP1) was a receptor overexpressed on the BBB. Angiopep-2, a specific ligand of LRP1, exhibited a high binding efficiency with LRP1. Additionally, ICA and TSIIA, drugs with neuroprotective effects are loaded into the liposomes, so that the liposomes not only have an effective BBB penetration effect, but also have a potential anti-AD effect. The prepared Ang2-ICA/TSIIA liposomes appeared narrow dispersity and good stability with a diameter of 110 nm, and a round morphology. Cell uptake observations, BBB models in vitro, and imaging analysis in vivo showed that Ang2-ICA/TSIIA liposomes not only penetrate the BBB through endocytosis, but also accumulate in N2a cells or brain tissue. The pharmacodynamic analysis in vivo demonstrated that Ang2-ICA/TSIIA liposomes could improve AD-like pathological features in APP/PS1 mice, including inhibiting neuroinflammation and oxidative stress, reducing apoptosis, protecting neurons, and improving cognitive function. Therefore, Ang2-ICA/TSIIA liposomes are considered a potentially effective therapeutic strategy for AD.
Double-sided unidirectional reflectivity
Creators: name: Ramirez-Hernandez, J.
name: Izrailev, F. M.
name: Makarov, N. M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We study the effect of unidirectional reflectivity in the bilayer optical model with the balanced loss/gain terms. It was found that if the impedances characterizing the scattering part are different from those describing the leads, a new effect of double-sided unidirectional reflectivity emerges. In this case the vanishing of reflectivity occurs either for the left or right reflectivity, depending on the frequency of scattering wave. It is shown that the alternation of the unidirectional reflectivity from the left to the right can occur even if the corresponding Hamiltonian is non-PT-symmetric. Our analytical results are demonstrated by numerical data.
description: 11 pages, 11 figures
Additional file 6: Table S2. of A novel genomic signature predicting FDG uptake in diverse metastatic tumors
Creators: name: Crespo-Jara, Aurora
name: Redal-Peña, Maria
name: Martinez-Navarro, Elena
name: Sureda, Manuel
name: Fernandez-Morejon, Francisco
name: Garcia-Cases, Francisco
name: Manzano, Ramon
name: Brugarolas, Antonio
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Correlation coefficient (CC) on SUV of ssGSEA scores with the C2 subset from the MSigDB v5.1 in the training dataset (p
Quantizing polaritons in inhomogeneous dissipative systems
Creators: name: Drezet, Aurélien
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this article we provide a a general analysis of canonical quantization for polaritons in dispersive and dissipative electromagnetic media. We compare several approaches based either on the Huttner Barnett model [B. Huttner, S. M. Barnett, Phys. Rev. A \textbf{46}, 4306 (1992)] or the Green function, Langevin noise method [T. Gruner, D.-G. Welsch, Phys. Rev. A \textbf{53}, 1818 (1996)] which includes only material oscillators as fundamental variables. We show in order to preserve unitarity, causality and time symmetry one must necessarily include with an equal footing both electromagnetic modes and material fluctuations on the evolution equations. This becomes particularly relevant for all nanophotonics and plasmonics problems involving spatially localized antennas or devices.
description: This paper is submitted for publication (any comments are welcome)
Additional file 4: Table S1. of A novel genomic signature predicting FDG uptake in diverse metastatic tumors
Creators: name: Crespo-Jara, Aurora
name: Redal-PeĂąa, Maria
name: Martinez-Navarro, Elena
name: Sureda, Manuel
name: Fernandez-Morejon, Francisco
name: Garcia-Cases, Francisco
name: Manzano, Ramon
name: Brugarolas, Antonio
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Marine Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Biological processes related to the signature genes (Consensus Pathway Database, release 31 ( http://ConsensusPathDB.org )). (DOCX 33Â kb)
title: ADCO, Cartulaire de Cîteaux pour les possessions d'Aloxe (XVe siècle), Cart. 182 (11 H 233), 105 folios, f. 0053
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour les possessions d'Aloxe (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 182 (11 H 233), 105 folios, f. 0053, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions d'Aloxe (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 182 (11 H 233), 105 folios, f. 0053, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Spin dynamics and spin-dependent recombination of a polaron pair under a strong ac drive
Creators: name: Malla, R. K.
name: Raikh, M. E.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study theoretically the recombination within a pair of two polarons in magnetic field subject to a strong linearly polarized ac drive. Strong drive implies that the Zeeman frequencies of the pair-partners are much smaller than the Rabi frequency, so that the rotating wave approximation does not apply. What makes the recombination dynamics nontrivial, is that the partners recombine only when they form a singlet, S. By admixing singlet to triplets, the drive induces the triplet recombination as well. We calculate the effective decay rate of all four spin modes. Our main finding is that, under the strong drive, the major contribution to the decay of the modes comes from short time intervals when the driving field passes through zero. When the recombination time in the absence of drive is short, fast recombination from S leads to anomalously slow recombination from the other spin states of the pair. We show that, with strong drive, this recombination becomes even slower. The corresponding decay rate falls off as a power law with the amplitude of the drive.
Food aid, cash transfers and producer prices in Ethiopia
Creators: name: Arega, Meron Assefa
name: Shively, Gerald
name: Arega, Meron Assefa
name: Shively, Gerald
Publisher: name: Unknown
Year: 2019
Subjects: subject: Agricultural Finance
subject: Food Security and Poverty
subject: emergency relief
subject: Ethiopia
subject: food aid
subject: PSNP
subject: SUR

description: We measured the producer price impacts of food and cash transfer programmes in Ethiopia using monthly panel data from 37 zones in four major regions over the period January 2007 to December 2010. We studies the independent and joint impacts of Ethiopia’s Productive Safety Net Programme (PSNP) and emergency relief programmes on producer prices for teff, wheat and maize. We estimated a series of dynamic, fixed-effects and seemingly unrelated regression (SUR) models. The results indicate that food aid allocated both by the PSNP and emergency relief programmes has either no discernible correlation with subsequent prices, or a weak, negative correlation. This suggests no strong disincentive effect of food aid on agricultural producers. The magnitudes of the correlations between prices and seasonal and time trends are substantially stronger than those associated with cash and grain transfers to local markets.
Proof Diagrams for Multiplicative Linear Logic: Syntax and Semantics
Creators: name: Acclavio, Matteo
Publisher: name: arXiv
Year: 2017
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Category Theory (math.CT)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: 18D10, 03b47, 18C50, 03B70

description: Proof nets are a syntax for linear logic proofs which gives a coarser notion of proof equivalence with respect to syntactic equality together with an intuitive geometrical representation of proofs. In this paper we give an alternative $2$-dimensional syntax for multiplicative linear logic derivations. The syntax of string diagrams authorizes the definition of a framework where the sequentializability of a term, i.e. deciding whether the term corresponds to a correct derivation, can be verified in linear time. Furthermore, we can use this syntax to define a denotational semantics for multiplicative linear logic with units by means of equivalence classes of proof diagrams modulo a terminating rewriting.
description: pre-print, submitted
Dual-responsive nanosystem based on TGF-β blockade and immunogenic chemotherapy for effective chemoimmunotherapy
Creators: name: Huang, Xiaoxian
name: Han, Lingfei
name: Wang, Ruyi
name: Zhu, Wanfang
name: Zhang, Ning
name: Qu, Wei
name: Liu, Wenyuan
name: Liu, Fulei
name: Feng, Feng
name: Xue, Jingwei
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Cell Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: The antitumor immune response induced by chemotherapy has attracted considerable attention. However, the immunosuppressive tumor microenvironment hinders the immune activation effect of cancer chemotherapy. TGF-β plays a key role in driving tumor immunosuppression and can prevent effective antitumor immune response through multiple roles. In this study, a dual-responsive prodrug micelle (PAOL) is designed to co-deliver LY2109761 (a TGF-β receptor I/II inhibitor) and oxaliplatin (OXA, a conventional chemotherapy) to remodel tumor microenvironment and trigger immunogenic cell death (ICD) to induce antitumor immunity response. Under hypoxia tumor environment, the polyethylene glycol shell of the micelle cleavages, along with the release of LY2109761 and OXA prodrug. Cytotoxic effect of OXA is then activated by glutathione-mediated reduction in tumor cells and the activated OXA significantly enhances tumor immunogenicity and promotes intratumoral accumulation of cytotoxic T lymphocytes. Meanwhile, TGF-β blockade through LY2109761 reprograms tumor microenvironment by correcting the immunosuppressive state and regulating tumor extracellular matrix, which further maintaining OXA induced immune response. Therefore, due to the capability of boosting tumor-specific antitumor immunity, the bifunctional micelle presents markedly synergistic antitumor efficacies and provides a potent therapeutic strategy for chemoimmunotherapy of solid tumors.
title: Climate change or irrigated agriculture – what drives the water level decline of Lake Urmia
Creators: name: Schulz, Stephan
name: Darehshouri, Sahand
name: Hassanzadeh, Elmira
name: Tajrishy, Massoud
name: Schüth, Christoph
Publisher: name: Springer Nature
Year: 2020

description: Lake Urmia is one of the largest hypersaline lakes on earth with a unique biodiversity. Over the past two decades the lake water level declined dramatically, threatening the functionality of the lake’s ecosystems. There is a controversial debate about the reasons for this decline, with either mismanagement of the water resources, or climatic changes assumed to be the main cause. In this study we quantified the water budget components of Lake Urmia and analyzed their temporal evolution and interplay over the last five decades. With this we can show that variations of Lake Urmia’s water level during the analyzed period were mainly triggered by climatic changes. However, under the current climatic conditions agricultural water extraction volumes are significant compared to the remaining surface water inflow volumes. Changes in agricultural water withdrawal would have a significant impact on the lake volume and could either stabilize the lake, or lead to its complete collapse.
Additional file 3: Table S6. of A novel genomic signature predicting FDG uptake in diverse metastatic tumors
Creators: name: Crespo-Jara, Aurora
name: Redal-PeĂąa, Maria
name: Martinez-Navarro, Elena
name: Sureda, Manuel
name: Fernandez-Morejon, Francisco
name: Garcia-Cases, Francisco
name: Manzano, Ramon
name: Brugarolas, Antonio
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Marine Biology
subject: Cancer
subject: Plant Biology

description: Detailed tumor histologies of the patients in the training and validation datasets. (DOCX 17Â kb)
Job design @ Eurotux
Creators: name: Sila, Marlene
Publisher: name: Conferência - Investigação e Intervenção em Recursos Humanos
Year: 2019

description: A Eurotux Informática SA em conjunto com a ITMZ, a DIPCODE e a MORE Sec constituem o Grupo Eurotux, especialistas em planeamento, integração e implementação de sistemas informáticos, oferecendo soluções de tecnologias de informação construídas à medida das necessidades dos clientes. Criada em 2000, junta a excelência técnica e científica a uma gestão prudente, que sempre lhe permitiu um crescimento sustentado, apoiado em elevados capitais próprios e em excelentes indicadores de resultados, liquidez e solvabilidade, que lhe valeram diversos galardões. Pelo profundo domínio que possui nas áreas específicas em que trabalha, consolidou-se como um player de referência no mercado. A sua equipa técnica é composta por profissionais altamente qualificados em integração e administração de sistemas. Distinguida mais do que uma vez como uma das melhores empresas para trabalhar em Portugal, a Eurotux tem privilegiado o investimento em políticas de capital humano com o objetivo de atração, desenvolvimento e retenção de talento essencial para a sustentabilidade e crescimento dos seus negócios. Desta preocupação surgiram diferentes práticas de gestão de recursos humanos, incluindo a necessidade de alteração e evolução ao nível do job design. O Job Design é uma função central da gestão de recursos humanos e está relacionado com a especificação de conteúdos, métodos e relações de trabalho. Tudo isto para procurar satisfazer as necessidades da organização e do colaborador (aspetos sociais e pessoais) e alcançar objetivos previamente definidos.
description: Conferência - Investigação e Intervenção em Recursos Humanos, n. 9 (2019): IX Conferência Internacional de Investigação e Intervenção em RH
The globular cluster system of NGC 1316 IV. Nature of the star cluster complex SH2
Creators: name: Richtler, T.
name: Husemann, B.
name: Hilker, M.
name: Puzia, T. H.
name: Bresolin, F.
name: Gómez, M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The light of the merger remnant NGC 1316 is dominated by old and intermediate-age stars. The only sign of current star formation in this big galaxy is the HII region SH2, an isolated star cluster complex with a ring-like morphology and an estimated age of 0.1 Gyr at a galactocentric distance of about 35 kpc. A nearby intermediate-age globular cluster, surrounded by weak line emission and a few more young star clusters, is kinematically associated. The origin of this complex is enigmatic. The nebular emission lines permit a metallicity determination which can discriminate between a dwarf galaxy or other possible precursors. We used the Integrated Field Unit of the VIMOS instrument at the Very Large Telescope of the European Southern Observatory to study the morphology, kinematics, and metallicity employing line maps, velocity maps, and line diagnostics of a few characteristic spectra. The line ratios of different spectra vary, indicating highly structured HII regions, but define a locus of uniform metallicity. The strong-line diagnostic diagrams and empirical calibrations point to a nearly solar or even super-solar oxygen abundance. The velocity dispersion of the gas is highest in the region offset from the bright clusters. Star formation may be active on a low level. There is evidence for a large-scale disk-like structure in the region of SH2, which would make the similar radial velocity of the nearby globular cluster easier to understand. The high metallicity does not fit to a dwarf galaxy as progenitor. We favour the scenario of a free-floating gaseous complex having its origin in the merger 2 Gyr ago. Over a long period the densities increased secularly until finally the threshold for star formation was reached. SH2 illustrates how massive star clusters can form outside starbursts and without a considerable field population.
description: 10 pages, 5 figures, accepted for Astronomy & Astrophysics
title: Alcatraz Ferry Embarkation
title: Endangered Species Act Section 7(a)(2) Biological Opinion and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Response for the Alcatraz Ferry Embarkation Project in San Francisco Bay (NPS File No. L76 (GOGA-PL))
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2017

description: ESA Section 7 Consultation ; WCRO-2016-00527
Transcriptome analysis of two soybean cultivars identifies an aluminum respon-sive antioxidant enzyme GmCAT1
Creators: name: Li, Weiyu
name: Sun, Yunjin
name: Wang, Bo
name: Xie, Hao
name: Wang, Jingxuan
name: Nan, Zhangjie
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: This study investigated the antioxidant defense system involved in the tolerance of soybean (Glycine max) to aluminum (Al) stress. Physiological assays showed that the amount of superoxide free radicals (O2−), hydrogen peroxide (H2O2), and malondialdehyde (MDA) were significantly lower in an Al-resistant soybean cultivar (cv. PI416937) than in an Al-sensitive soybean cultivar (cv. Huachun18). Comparative analysis of microarray data from both genotypes following Al-stress treatment revealed that the expression of a series of antioxidant enzymes genes was induced in the Al-resistant cultivar. The quantitative real time-PCR (qRT-PCR) assay showed that the transcript levels of genes encoding antioxidant enzymes, including GmCAT1, GmPOD1, GmGST1, GmAPX, GmGSH1, and GmSOD, were higher in the Al-resistant cultivar than in the Al-sensitive cultivar in Al-stress conditions. Furthermore, GmCAT1-overexpressing Arabidopsis plants had improved tolerance to Al-stress and lower O2−, H2O2, and MDA contents than wild-type plants. Therefore, providing evidence that the antioxidant defense system is essential for Al tolerance in soybean. Al: aluminum; O2−: superoxide free radicals; ROS: reactive oxygen species; H2O2: hydrogen peroxide; MDA: malondialdehyde; qRT-PCR: quantitative reverse transcription polymerase chain reaction; GO: gene ontology; WT: wild type; MS medium: Murashige and Skoog medium Antioxidant defense system play essential roles in soybean Al tolerance. The results are of great significance in understanding the molecular mechanism of Al stress responses in soybean.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Cart. 188 (11 H 73), f. 0175r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Archives départementales de la Côte-d'Or, Cart. 188 (11 H 73), f. 0175r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Archives départementales de la Côte-d'Or, Cart. 188 (11 H 73), f. 0175r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
On Cracking of Charged Anisotropic Polytropes
Creators: name: Azam, M.
name: Mardan, S. A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: Recently in \cite{34}, the role of electromagnetic field on the cracking of spherical polytropes has been investigated without perturbing charge parameter explicitly. In this study, we have examined the occurrence of cracking of anisotropic spherical polytropes through perturbing parameters like anisotropic pressure, energy density and charge. We consider two different types of polytropes in this study. We discuss the occurrence of cracking in two different ways $(i)$ by perturbing polytropic constant, anisotropy and charge parameter $(ii)$ by perturbing polytropic index, anisotropy and charge parameter for each case. We conclude that cracking appears for a wide range of parameters in both cases. Also, our results are reduced to \cite{33} in the absence of charge.
description: 24 pages, 10 figures
Fabrication of bio-engineered chitosan nanoformulations to inhibition of bacterial infection and to improve therapeutic potential of intestinal microflora, intestinal morphology, and immune response in infection induced rat model
Creators: name: Wan, Xiao
name: Liu, Liu
name: Ding, Lu
name: Zhu, Zhiqiang
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Overdosage of antibiotics used to prevent bacterial infections in the human and animal gastrointestinal tract would result in disturbing of intestinal barrier, significant misbalancing effects of intestinal microflora and persuading bacterial resistance. The main objective of the present investigation is to design and develop novel combinations of organic curcumin (Cur) and antimicrobial peptide (Amp) loaded chitosan nanoformulations (Cur/Amp@CS NPs) to improve significant effects on antibacterial action, immune response, intestine morphology, and intentional microflora. The antibacterial efficiency of the prepared nanoformulations was evaluated using Escherichia coli (E. coli) induced bacterial infections in GUT of Rat models. Further, we studied the cytocompatibility, inflammatory responses, α-diversity, intestinal morphology, and immune responses of treated nanoformulations in rat GUT models. The results indicated that Cur/Amp@CS NPs are greatly beneficial for intestinal microflora and could be a prodigious alternative of antibiotics.
Additional file 2: Table S4. of A novel genomic signature predicting FDG uptake in diverse metastatic tumors
Creators: name: Crespo-Jara, Aurora
name: Redal-PeĂąa, Maria
name: Martinez-Navarro, Elena
name: Sureda, Manuel
name: Fernandez-Morejon, Francisco
name: Garcia-Cases, Francisco
name: Manzano, Ramon
name: Brugarolas, Antonio
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Cancer

description: Complete list of the 909 probes selected for the generation of the multivariable model along with their correspondent regression coefficient. (DOCX 110Â kb)
title: Gestion du passif de l'activité minière. Rapport scientifique
Creators: name: Garcin, Manuel
name: Richard, Didier
name: Liébault, Frédéric
name: Recking, Alain
name: Piton, Guillaume
name: Sabinot, Catherine
name: Worliczek, Élisabeth
name: Lesimple, Stéphane
name: Bertrand, Mélanie
name: Gastaldi, Yann
name: Burlat, Tom
name: Gosset, Lucie
name: Pidjo, A-Tena
Publisher: name: CNRT Nickel et son environnement
Year: 2018
Subjects: subject: FOS: Earth and related environmental sciences
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: Programme Gestion du passif. (Tome Nickel et Environnement)
Vegetable production technical efficiency and technology gaps in Ghana
Creators: name: Tsiboe, Francis
name: Asravor, Jacob
name: Osei, Evelyn
name: Tsiboe, Francis
name: Asravor, Jacob
name: Osei, Evelyn
Publisher: name: Unknown
Year: 2019
Subjects: subject: Crop Production/Industries
subject: Research and Development/Tech Change/Emerging Technologies
subject: Ghana
subject: efficiency
subject: okra
subject: pepper
subject: technology gap
subject: tomato

description: This study characterises the nature of the vegetable production shortfall throughout Ghana for remedial action to be taken. By applying the meta-stochastic frontier analysis to a sample of okra, pepper and tomato farmers, the results show that the ranking of production inputs in production is in the order land, hired labour, fertiliser, pesticide and family labour. Furthermore, the results also suggest that vegetable production is characterised by diseconomies of scale. Technical efficiency for okra, pepper and tomato farmers in Ghana is estimated at 54%, 74% and 58% respectively, and this has generally increased for okra and pepper but remained stable for tomato. Technology gaps are close to non-existent for pepper cultivation, modest for tomato, and severe for okra. This implies that, whilst there is no potential for production gain from redistributing pepper technology throughout Ghana, there is limited potential for tomato and substantial potential for okra. Pepper farmers could potentially benefit from managerial improvements.
Optical selection rules for excitonic Rydberg series in the massive Dirac cones of hexagonal 2D materials
Creators: name: Gong, Pu
name: Yu, Hongyi
name: Wang, Yong
name: Yao, Wang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the optical transition selection rules for excitonic Rydberg series formed in massive Dirac cones. The entanglement of the exciton envelop function with the pseudospin texture leads to anomalous selection rules for one-photon generation of excitons, where $d$-orbitals can be excited with the opposite helicity selection rule from the $s$-orbitals in a given valley. The trigonal warping effects in realistic hexagonal lattices further renders more excited states bright, where $p$-orbitals can also be accessed by one-photon excitation with the opposite valley selection rules to the $s$-orbitals. The one-photon generation of exciton in the various states and the intra-excitonic transition between these states are both dictated by the discrete in-plane rotational symmetry of the lattices, and our results show that in hexagonal 2D materials the symmetry allowed transitions are enabled when trigonal warping effects are included in the massive Dirac fermion model. In monolayer transition metal dichalcogenides where excitons can be generated by visible light and intra-excitonic transitions can be induced by infrared light, we give the strength of these optical transitions, estimated using modified hydrogen-like envelope functions combined with the optical transition matrix elements between the Bloch states calculated at various $k$ points.
description: 9 pages, 2 figures
Mimicking chronic glaucoma over 6 months with a single intracameral injection of dexamethasone/fibronectin-loaded PLGA microspheres
Creators: name: Aragón-Navas, Alba
name: Rodrigo, María J.
name: Garcia-Herranz, David
name: Martinez, Teresa
name: Subias, Manuel
name: Mendez, Silvia
name: Ruberte, Jesús
name: Pampalona, Judit
name: Bravo-Osuna, Irene
name: Garcia-Feijoo, Julian
name: Pablo, Luis E.
name: Garcia-Martin, Elena
name: Herrero-Vanrell, Rocío
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: To create a chronic glaucoma animal model by a single intracameral injection of biodegradable poly lactic-co-glycolic acid (PLGA) microspheres (Ms) co-loaded with dexamethasone and fibronectin (MsDexaFibro). MsDexaFibro were prepared by a water-in-oil-in-water emulsion method including dexamethasone in the organic phase and fibronectin in the inner aqueous phase. To create the chronic glaucoma model, an interventionist and longitudinal animal study was performed using forty-five Long Evans rats (4-week-old). Rats received a single intracameral injection of MsDexafibro suspension (10%w/v) in the right eye. Ophthalmological parameters such as clinical signs, intraocular pressure (IOP), neuro-retinal functionality by electroretinography (ERG), retinal structural analysis by optical coherence tomography (OCT), and histology were evaluated up to six months. According to the results obtained, the model proposed was able to induce IOP increasing in both eyes over the study, higher in the injected eyes up to 6 weeks (p < 0.05), while preserving the ocular surface. OCT quantified progressive neuro-retinal degeneration (mainly in the retinal nerve fiber layer) in both eyes but higher in the injected eye. Ganglion cell functionality decreased in injected eyes, thus smaller amplitudes in PhNR were detected by ERG. In conclusion, a new chronic glaucoma animal model was created by a single injection of MsDexaFibro very similar to open-angle glaucoma occurring in humans. This model would impact in different fields such as ophthalmology, allowing long period of study of this pathology; pharmacology, evaluating the neuroprotective activity of active compounds; and pharmaceutical technology, allowing the correct evaluation of the efficacy of long-term sustained ocular drug delivery systems.
Chitranuvad: Adapting Multi-Lingual LLMs for Multimodal Translation
Creators: name: Khan, Shaharukh
name: Tarun, Ayush
name: Faraz, Ali
name: Kamble, Palash
name: Dahiya, Vivek
name: Pokala, Praveen
name: Kulkarni, Ashish
name: Khatri, Chandra
name: Ravi, Abhinav
name: Agarwal, Shubham
Publisher: name: arXiv
Year: 2025
Subjects: subject: Computation and Language (cs.CL)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In this work, we provide the system description of our submission as part of the English to Lowres Multimodal Translation Task at the Workshop on Asian Translation (WAT2024). We introduce Chitranuvad, a multimodal model that effectively integrates Multilingual LLM and a vision module for Multimodal Translation. Our method uses a ViT image encoder to extract visual representations as visual token embeddings which are projected to the LLM space by an adapter layer and generates translation in an autoregressive fashion. We participated in all the three tracks (Image Captioning, Text only and Multimodal translation tasks) for Indic languages (ie. English translation to Hindi, Bengali and Malyalam) and achieved SOTA results for Hindi in all of them on the Challenge set while remaining competitive for the other languages in the shared task.
On the induced impacts of French pesticide policies: some macroeconomic assessments
Creators: name: Bareille, François
name: Gohin, Alexandre
name: Bareille, François
name: Gohin, Alexandre
Publisher: name: Unknown
Year: 2020
Subjects: subject: Agricultural and Food Policy
subject: Environmental Economics and Policy
subject: Agriculture
subject: pesticide taxation scheme
subject: land-use change
subject: carbon emissions

description: The applications of synthetic pesticides by farmers generate fierce debates in France. This paper offers an original macroeconomic quantification of their economic and environmental impacts. We first reveal the statistically significant influence of the prices of crops and pesticides on these application. This influence is lower for cereals than other crops. We then simulate some economic and environmental impacts of future potential French policies. We find, as expected, that a simple tax policy reduces pesticide use and hurts the economic situation of French farmers and food processors. The French livestock sectors are also negatively impacted. We also find that such a simple policy will increase nitrogen pollution and greenhouse gas emissions due to global land use changes. Finally, policy insights regarding these macroeconomic results are discussed.
Machine-Learning Based Assessment of Cystic Fibrosis
Creators: name: Chong Chie, Juan Antonio Kim Hoo
Publisher: name: Purdue University Graduate School
Year: 2024
Subjects: classificationCode: 400607
subject: Signal processing
classificationCode: 460306
subject: Image processing
classificationCode: 461199
subject: Machine learning not elsewhere classified

description: Cystic fibrosis is a genetic disease that affects over 162,428 people worldwide. Currently, assessing cystic fibrosis from medical images requires a trained expert to manually annotate regions in the patient's lungs to determine the stage and severity of the disease. This process takes a substantial amount of time and effort to achieve an accurate assessment. Recent advancements in machine learning and deep learning have been effective in solving classification, decision-making, identification, and segmentation problems in various disciplines. In medical research, these techniques have been used to perform image analyses that aid in organ identification, tissue classification, and lesion segmentation, which reduces the time required for physicians to analyze medical images. However, these techniques have yet to be widely applied in the assessment of cystic fibrosis. This thesis describes an automated framework employed to assess the severity and extent of cystic fibrosis. The framework comprises three analysis stages: airways analysis, texture analysis, and lung lesions detection, that are utilized to extract cystic fibrosis features from CT scans, and which are used to assess the severity and extent of cystic fibrosis. The framework achieved an accuracy of 86.96\% in the staging process. The main contribution of this work is the development of a data-driven methodology used to design a quantitative cystic fibrosis staging and grading model.
F-TRIDYN: A Binary Collision Approximation Code for Simulating Ion Interactions with Rough Surfaces
Creators: name: Drobny, Jon
name: Curreli, Davide
name: Hayes, Alyssa
name: Ruzic, David N.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Fractal TRIDYN (F-TRIDYN) is a modified version of the widely used Monte Carlo, Binary Collision Approximation code TRIDYN that includes an explicit model of surface roughness and additional output modes for coupling to plasma edge and material codes. Surface roughness plays an important role in ion irradiation processes such as sputtering; roughness can significantly increase the angle of maximum sputtering and change the maximum observed sputtering yield by a factor of 2 or more. The complete effect of surface roughness on sputtering and other ion irradiation phenomena is not completely understood. Many rough surfaces can be consistently and realistically modeled by fractals, using the fractal dimension and fractal length scale as the sole input parameters. F-TRIDYN includes a robust fractal surface algorithm that is more computationally efficient than those in previous fractal codes and which reproduces available experimental sputtering data from rough surfaces. Fractals provide a compelling path toward a complete and concise understanding of the effect that surface geometry plays on the behavior of plasma-facing materials. F-TRIDYN is a flexible code for simulating ion-solid interactions and coupling to plasma and material codes for multiscale modeling.
description: Submitted to Journal of Nuclear Materials
Additional file 1: of A novel genomic signature predicting FDG uptake in diverse metastatic tumors
Creators: name: Crespo-Jara, Aurora
name: Redal-PeĂąa, Maria
name: Martinez-Navarro, Elena
name: Sureda, Manuel
name: Fernandez-Morejon, Francisco
name: Garcia-Cases, Francisco
name: Manzano, Ramon
name: Brugarolas, Antonio
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Supplementary Methods. (DOCX 29Â kb)
PLUS (Platform Labour in Urban Spaces) Work Package 6 Framing Social Policies (public data)
Creators: name: Spencer, Neil
name: Kampouri, Eleni
Publisher: name: University of Hertfordshire
Year: 2022

description: An archive of the publicly available data used for Work Package 6 (Framing Social Policies) for the Horizon 2020 PLUS (Platform Labour in Urban Spaces) project. Data available on a restricted basis to PLUS project researchers [PLUS_15_PLUS.WP6 Framing social policies (restricted London data)] is available at https://herts365.sharepoint.com/:f:/r/sites/PLUSProjectTeamatUH/Shared%20Documents/Data%20Archive/PLUS_15_PLUS.WP6%20Framing%20social%20policies%20(restricted%20London%20data)?csf=1&web=1&e=o7szo4.
Optically controlled orbital angular momentum generation in a polaritonic quantum fluid
Creators: name: Luk, Samuel M. H.
name: Kwong, Nai-Hang
name: Lewandowski, Przemyslaw
name: Schumacher, Stefan
name: Binder, Rolf
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Applications of the orbital angular momentum (OAM) of light range from the next generation of optical communication systems to optical imaging and optical manipulation of particles. Here we propose a micron-sized semiconductor source which emits light with pre-defined OAM components. This source is based on a polaritonic quantum fluid. We show how in this system modulational instabilities can be controlled and harnessed for the spontaneous formation of OAM components not present in the pump laser source. Once created, the OAM states exhibit exotic flow patterns in the quantum fluid, characterized by generation-annihilation pairs. These can only occur in open systems, not in equilibrium condensates, in contrast to well-established vortex-antivortex pairs.