cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(1942) Willliam Spink
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Four dodecanoic acid derivatives from the cold-seep-derived fungus Cladosporium cladosporioides 8-1
Creators: name: Li, Chang-Peng
name: Song, Yin-Ping
name: Liang, Xiao-Rui
name: Ji, Nai-Yun
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: Virology

description: Two new compounds, cladospolides I (1) and J (2), together with two new naturally occurring ones, methyl 11-hydroxy-4-oxododecanoate (3) and 11-hydroxy-4-oxododecanoic acid (4), were isolated from the culture extract of the cold-seep sediment-derived fungus Cladosporium cladosporioides 8-1. Their structures and configurations were established by analysis of 1D/2D NMR, MS, ECD, and specific optical rotation data. Compound 3 was possibly formed by methyl esterification of 4 during the purification process due to the utilization of methanol. All compounds were evaluated for inhibition of four marine phytoplankton species and five marine-derived bacteria.
Details on the odour rating procedure from The scent of attractiveness: levels of reproductive hormones explain individual differences in women's body odour
Creators: name: Lobmaier, Janek S.
name: Fischbacher, Urs
name: Wirthmüller, Urs
name: Knoch, Daria
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Individuals are thought to have their own distinctive body odour which reportedly plays an important role in mate choice. In the present study we investigated individual differences in body odours of women and examined whether some women generally smell more attractive than others or whether odour preferences are a matter of individual taste. We then explored whether levels of reproductive hormones explain women's body odour attractiveness, to test the idea that body odour attractiveness may act as a chemosensory marker of reproductive fitness. Fifty-seven men rated body odours of 28 healthy, naturally cycling women of reproductive age. We collected all odours at peak fertility to control for menstrual cycle effects on body odour attractiveness. Women's salivary oestradiol, progesterone, testosterone and cortisol levels were assessed at the time of odour collection to test whether hormone levels explain body odour attractiveness. We found that the men highly agreed on how attractive they found women's body odours. Interestingly, women's body odour attractiveness was predicted by their oestradiol and progesterone levels: The higher a woman's levels of oestradiol and the lower her levels of progesterone, the more attractive her body odour was rated. In showing that women's body odour attractiveness is explained by levels of female reproductive hormones, but not by levels of cortisol or testosterone, we provide evidence that body odour acts as a valid cue to potential fertility.
Activation Function 2 in the Human Androgen Receptor Ligand Binding Domain Mediates Interdomain Communication with the NH 2 -terminal Domain
Creators: name: Voegel, Johannes J.
name: Kemppainen, Jon A.
name: Gronemeyer, Hinrich
name: He, Bin
name: Wilson, Elizabeth M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: Activation function 2 in the ligand binding domain of nuclear receptors forms a hydrophobic cleft that binds the LXXLL motif of p160 transcriptional coactivators. Here we provide evidence that activation function 2 in the androgen receptor serves as the contact site for the androgen dependent NH(2)- and carboxyl-terminal interaction of the androgen receptor and only weakly interacts with p160 coactivators in an LXXLL-dependent manner. Mutagenesis studies indicate that it is the NH(2)-/carboxyl-terminal interaction that is required by activation function 2 to stabilize helix 12 and slow androgen dissociation critical for androgen receptor activity in vivo. The androgen receptor recruits p160 coactivators through its NH(2)-terminal and DNA binding domains in an LXXLL motif-independent manner. The results suggest a novel function for activation function 2 and a unique mechanism of nuclear receptor transactivation.
(1939) Mary Adelaide Bainbridge
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Optical spectroscopic observations of blazars and gamma-ray blazar candidates in the Sloan Digital Sky Survey Data Release Nine
Creators: name: Massaro, F.
name: Masetti, N.
name: D'Abrusco, R.
name: Paggi, A.
name: Funk, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present an analysis of the optical spectra available in the Sloan Digital Sky survey data release nine (SDSS DR9) for the blazars listed in the ROMA-BZCAT and for the gamma-ray blazar candidates selected according to their IR colors. First, we adopt a statistical approach based on MonteCarlo simulations to find the optical counterparts of the blazarslisted in the ROMA-BZCAT catalog. Then we crossmatched the SDSS spectroscopic catalog with our selected samples of blazars and gamma-ray blazar candidates searching for those with optical spectra available to classify our blazar-like sources and, whenever possible, to confirm their redshifts. Our main objectives are determining the classification of uncertain blazars listed in the ROMA-BZCAT and discovering new gamma-ray blazars. For the ROMA-BZCAT sources we investigated a sample of 84 blazars confirming the classification for 20 of them and obtaining 18 new redshift estimates. For the gamma-ray blazars, indicated as potential counterparts of unassociated Fermi sources or with uncertain nature, we established the blazar-like nature of 8 out the 27 sources analyzed and confirmed 14 classifications.
description: 7 pages, 2 figures, 4 tables, AJ published in 2014 (pre-proof version)
Prodigious chemotypic variance in essential oil constituents of Blumea eriantha DC. herb and root
Creators: name: Joshi, Rajesh K.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: The essential oil of Blumea eriantha DC. (Asteraceae) herb (leaves and stems) (BEHO) and roots (BERO) was obtained by hydro-distillation and analyzed by GC–FID and GC–MS. The chemical constituents of BEHO and BERO were identified according to their mass spectra and relative retention indices. Fifty-two and thirty-eight compounds were identified, comprising 97.1% and 95.5% of the BEHO and BERO, respectively. The prodigious differences were observed in the major constituents of BEHO and BERO. The major compounds were chrysanthenone (52.8%) and 2,4-dimethylether phloroacetophenone (15.1%) (BEHO), 2,5-dimethoxy-p-cymene (31.3%), epi-α-cadinol (12.7%) and γ-cadinene (10.5%) (BERO). The BEHO found a higher concentration of oxygenated monoterpenes, while BERO with phenyl derivatives type of constituents.
Das Warburg Institute (1946)
Creators: name: Saxl, Fritz
Publisher: name: La Rivista di Engramma
Year: 2023
Subjects: Fritz Saxl
Aby Warburg
Warburg Library
Warburg Institute

description: In this short contribution, published in 1946 for the magazine “Neue Auslese”, Fritz Saxl writes a concise introduction to the Warburg Institute. Saxl emphasises how the construction of the Library was generated around the scientific imprint left by its founder, Aby Warburg, which can be summarised as the investigation of the survival of certain forms of expression in the history of culture.
slerpID_BL_sub01_SIappendices.docx from The dynamic role of the ilio-sacral joint in jumping frogs.
Creators: name: Richards, Christopher T.
name: Eberhard, Enrico A.
name: Collings, Amber J.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 110601 Biomechanics
subject: FOS: Health sciences

description: SI Appendices 1, 2, 3 and SI figure legends
New glucosidated indole-quinazoline alkaloids from mangrove endophytic fungus Aspergillus fumigatus SAl12
Creators: name: Guo, Shili
name: Zhou, Haiming
name: Huang, Xin
name: Peng, Siyan
name: Li, Jiayi
name: Ding, Bo
name: Tao, Yiwen
name: Huang, Hongbo
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Two new glucosidated indole-containing quinazoline alkaloids designated fumigatosides G (1) and H (2) were isolated from mangrove-derived fungus Aspergillus fumigatus SAl12, together with the known analogues fumigatoside B (3) and fumiquinazoline J (4). The planar structures of the new compounds were elucidated by HR-MS and NMR spectroscopic data analyses. The absolute configurations were determined by comparison of electronic circular dichroic (ECD) spectra with that of the known compound fumigatoside B and with the calculated ECD spectrum. All these indole-quinazoline compounds were tested for anti-bacterial and cytotoxic activities.
Extracting Radial Velocities of A- and B-type Stars from Echelle Spectrograph Calibration Spectra
Creators: name: Becker, Juliette C.
name: Johnson, John Asher
name: Vanderburg, Andrew
name: Morton, Timothy D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present a technique to extract radial velocity measurements from echelle spectrograph observations of rapidly rotating stars ($V\sin{i} \gtrsim 50$ km s$^{-1}$). This type of measurement is difficult because the line widths of such stars are often comparable to the width of a single echelle order. To compensate for the scarcity of lines and Doppler information content, we have developed a process that forward-models the observations, fitting the radial velocity shift of the star for all echelle orders simultaneously with the echelle blaze function. We use our technique to extract radial velocity measurements from a sample of rapidly rotating A- and B-type stars used as calibrator stars observed by the California Planet Survey observations. We measure absolute radial velocities with a precision ranging from 0.5-2.0 km s$^{-1}$ per epoch for more than 100 A- and B-type stars. In our sample of 10 well-sampled stars with radial velocity scatter in excess of their measurement uncertainties, three of these are single-lined binaries with long observational baselines. From this subsample, we present detections of two previously unknown spectroscopic binaries and one known astrometric system. Our technique will be useful in measuring or placing upper limits on the masses of sub-stellar companions discovered by wide-field transit surveys, and conducting future spectroscopic binarity surveys and Galactic space-motion studies of massive and/or young, rapidly-rotating stars.
description: Accepted to ApJS
Limits of weighted graphs
Creators: name: Krolicki, Konrad
Publisher: name: Lancaster University
Year: 2020

description: This thesis concerns the actions of countable groups and associated Schreier graphs. In Chapters 1 and 2 we give the motivation and overview for the research presented in this thesis and we establish the basics regarding group actions, especially about Schreier graphs and amenability. Furthermore, we recall the idea of equationally compact actions of groups defined by Banaschewski. Finally, we show two results about equationally compact subgroups of infinite groups which answer two questions of Rajani and Prest. We start off Chapter 3 with recalling the construction of a space of rooted Schreier graphs which are associated with the actions of a group. A crucial notion related to the space of rooted Schreier graphs is that of a Benjamini-Schramm convergence of sequences of sparse graphs, which has connections with measure-preserving actions of groups. We are, however, particularly interested in actions which only preserve the measure class, i.e. the non-singular actions of groups. Let us notice that for such actions the classical theorem of Radon-Nikodym can be applied, which equips the graph structure on the space with an additional function on the edges which forms a cocycle. Thus, drawing inspiration from the space of rooted Schreier graphs, we construct a space of rooted Schreier cocycles of a group. Similarly as in the measure-preserving case, we obtain a correspondence between the space of cocycles and non-singular actions of groups. In the final chapter of the thesis the central notion is that of hyperfiniteness, which has strong ties to amenability. The definition of hyperfiniteness varies between the settings of sequences of graphs, graphings of the actions of groups and for equivalence relations. Broadly speaking, an object is hyperfinite if it is in some sense close to being finite. Thus, a sequence of graphs is hyperfinite if we can remove sets of arbitrarily small size relative to the size of graphs in such a way that the resulting objects have components of bounded size. On the other hand, a measure preserving group action yields an associated structure of a graphing on the space that it acts upon. If we can remove an arbitrarily small set from the probability space in such a way that the resulting graphing has bounded components then we call the action hyperfinite. In fact, these two notions of hyperfiniteness are strongly connected: by the theorem of Schramm, a measure preserving action is hyperfinite if and only if a sequence of graphs convergent to it is hyperfinite. We consider a weighted version of hyperfiniteness, one which is suitable for this setting and we obtain a similar result to that of Schramm’s in Chapter 4, namely that a limit action of a hyperfinite sequence of cocycles is hyperfinite. Finally, we find continuous actions which are isomorphic to a given Borel action and have the same Radon-Nikodym cocycle and we obtain examples of free continuous actions of exact groups with continuous Radon-Nikodym derivatives.
Correlated bursts and the role of memory range
Creators: name: Jo, Hang-Hyun
name: Perotti, Juan I.
name: Kaski, Kimmo
name: Kertesz, Janos
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: Inhomogeneous temporal processes in natural and social phenomena have been described by bursts that are rapidly occurring events within short time periods alternating with long periods of low activity. In addition to the analysis of heavy-tailed inter-event time distributions, higher-order correlations between inter-event times, called correlated bursts, have been studied only recently. As the possible mechanisms underlying such correlated bursts are far from being fully understood, we devise a simple model for correlated bursts by using a self-exciting point process with variable memory range. Here the probability that a new event occurs is determined by a memory function that is the sum of decaying memories of the past events. In order to incorporate the noise and/or limited memory capacity of systems, we apply two memory loss mechanisms, namely either fixed number or variable number of memories. By using theoretical analysis and numerical simulations we find that excessive amount of memory effect may lead to a Poissonian process, which implies that for memory effect there exists an intermediate range that will generate correlated bursts of magnitude comparable to empirical findings. Hence our results provide deeper understanding of how long-range memory affects correlated bursts.
description: 9 pages, 7 figures
AKAP350, a Multiply Spliced Protein Kinase A-anchoring Protein Associated with Centrosomes
Creators: name: Trotter, Kevin W.
name: Dransfield, Daniel T.
name: Hawley, Robert G.
name: Milgram, Sharon L.
name: Schmidt, P. Henry
name: Goldenring, James R.
name: Claudio, Jaime O.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: Protein kinase A-anchoring proteins (AKAPs) localize the second messenger response to particular subcellular domains by sequestration of the type II protein kinase A. Previously, AKAP120 was identified from a rabbit gastric parietal cell cDNA library; however, a monoclonal antibody raised against AKAP120 labeled a 350-kDa band in Western blots of parietal cell cytosol. Recloning has now revealed that AKAP120 is a segment of a larger protein, AKAP350. We have now obtained a complete sequence of human gastric AKAP350 as well as partial cDNA sequences from human lung and rabbit parietal cells. The genomic region containing AKAP350 is found on chromosome 7q21 and is multiply spliced, producing at least three distinct AKAP350 isoforms as well as yotiao, a protein associated with the N-methyl-D-aspartate receptor. Rabbit parietal cell AKAP350 is missing a sequence corresponding to a single exon in the middle of the molecule located just after the yotiao homology region. Two carboxyl-terminal splice variants were also identified. Both of the major splice variants showed tissue- and cell-specific expression patterns. Immunofluorescence microscopy demonstrated that AKAP350 was associated with centrosomes in many cell types. In polarized Madin-Darby canine kidney cells, AKAP350 localized asymmetrically to one pole of the centrosome, and nocodazole did not alter its localization. During the cell cycle, AKAP350 was associated with the centrosomes as well as with the cleavage furrow during anaphase and telophase. Several epithelial cell types also demonstrated noncentrosomal pools of AKAP350, especially parietal cells, which contained multiple cytosolic immunoreactive foci throughout the cells. The localization of AKAP350 suggests that it may regulate centrosomal and noncentrosomal cytoskeletal systems in many different cell types.
Porträt aus Büchern. Stichworte
Creators: name: Diers, Michael
Publisher: name: La Rivista di Engramma
Year: 2023
Subjects: Fritz Saxl
Gertrud Bing
Warburg Institute
Warburg Bibliothek
Studien
Vortragen

description: In this contribution, excerpted from the book edited by Michael Diers, Porträt aus Buchern (Hamburg 1993), Michael Diers explains the history of the Warburg Institute after its founder’s death. The author reconstructs the multifaceted history of the research institute by questioning sources of the time: from private and unpublished letters to reviews. Diers also reconstructs the fundamental history of the KBW's publishing activities through its most important series and titles.
(1935) George Percy Pickard
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Association of the D2 Dopamine Receptor Third Cytoplasmic Loop with Spinophilin, a Protein Phosphatase-1-interacting Protein
Creators: name: Oxford, Gerry S.
name: Milgram, Sharon L.
name: Smith, F. Donelson
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: Signaling through D2 class dopamine receptors is crucial to correct brain development and function, and dysfunction of this system is implicated in major neurological disorders such as Parkinson's disease and schizophrenia. To investigate potential novel mechanisms of D2 receptor regulation, the third cytoplasmic loop of the D2 dopamine receptor was used to screen a rat hippocampal yeast two-hybrid library. Spinophilin, a recently characterized F-actin and protein phosphatase-1-binding protein with a single PDZ domain was identified as a protein that specifically associates with this region of D2 receptors. A direct interaction between spinophilin and the D2 receptor was confirmed in vitro using recombinant fusion proteins. The portion of spinophilin responsible for interacting with the D2 third cytoplasmic loop was narrowed to a region that does not include the actin-binding domain, the PDZ domain, or the coiled-coil. This region is distinct from the site of interaction with protein phosphatase-1, and both D2 receptors and protein phosphatase-1 may bind spinophilin at the same time. The interaction is not mediated via the unique 29-amino acid insert in D2long; both D2long and D2short third cytoplasmic loops interact with spinophilin in vitro and in yeast two-hybrid assays. Expression of D2 receptors containing an extracellular hemagglutinin epitope in Madin-Darby canine kidney cells results in co-localization of receptor and endogenous spinophilin as determined by immunocytochemistry using antibodies directed against spinophilin and the HA tag. We hypothesize that spinophilin is important for establishing a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors to downstream signaling molecules and the actin cytoskeleton.
Efomycine U, a new C2-asymmetric elaiophylin derivative from Streptomyces malaysiensis DSM 4137
Creators: name: Xu, Jing
name: Wu, Jingwan
name: Zhou, Dongdong
name: Zhang, Xuexia
name: Leadlay, Peter F.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Virology

description: Chemical examination of an actinomycete strain Streptomyces malaysiensis DSM 4137 derived from a soil sample derived isolate Streptomyces sp. DSM 3816, yielded a new C2-asymmetric elaiophylin derivative efomycine U (1) and a known analogue halichoblelide D (2). These structures were unambiguously elucidated on the basis of extensive NMR spectroscopic and mass spectrometric analyses. All compounds isolated were subjected to antimicrobial, cytotoxic and immnosuppressive activities evaluation.
Gravitational self-force in non-vacuum spacetimes: an effective field theory derivation
Creators: name: Zimmerman, Peter
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper we investigate the motion of small compact objects in non-vacuum spacetimes using methods from effective field theory in curved spacetime. Although a vacuum formulation is sufficient in many astrophysical contexts, there are applications such as the role of the self-force in enforcing cosmic-censorship in the context of the overcharging problem, which necessitate an extension into the non-vacuum regime. The defining feature of the self-force problem in non-vacuum spacetimes is the coupling between gravitational and non-gravitational field perturbations. The formulation of the self-force problem for non-vacuum spacetimes was recently provided in simultaneous papers by Zimmerman and Poisson [1] and Linz, Friedmann, Wiseman [2]. Here we distinguish ourselves by working with the effective action rather than the field equations. The formalism utilizes the multi-index notation developed by Zimmerman and Poisson [1] to accommodate the coupling between the different fields. Using dimensional regularization, we arrive at a finite expression for the local self-force expressed in terms of multi-index quantities evaluated in the background spacetime. We then apply the formalism to compute the coupled gravitational self-force in two explicit cases. First, we calculate the self-force on a massive particle possessing scalar charge and moving in an scalarvac spacetime. We then derive an expression for the self-force on an electrically charged, massive particle moving in an electrovac spacetime. In both cases, the force is expressed as a sum of local terms involving tensors defined in the background spacetime and evaluated at the current position of the particle, as well as tail integrals that depend on the past history of the particle.
description: 41 pages. Submitted to PRD
slerpID_BL_sub01_SIappendices.docx from The dynamic role of the ilio-sacral joint in jumping frogs
Creators: name: Richards, Christopher T.
name: Eberhard, Enrico A.
name: Collings, Amber J.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 110601 Biomechanics
subject: FOS: Health sciences

description: SI Appendices 1, 2, 3 and SI figure legends
title: Single-shot all-digital approach for measuring the orbital angular momentum spectrum of light
Creators: name: Otte, Eileen
name: Bobkova, Valeriia
name: Trinschek, Sarah Christine
name: Rosales-Guzmán, C.
name: Denz, Cornelia
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2022
Subjects: subject: 530 Physics

description: Light fields carrying orbital angular momentum (OAM) offer a broad variety of applications in which especially an accurate determination of the respective OAM spectrum, i.e., unraveling the content of OAM by its topological charge ℓ, has become a main subject. Even though various techniques have been proposed to measure the OAM spectrum of such modes, many of them fail if optical vortices have to be considered in perturbed or dynamically changing experimental systems. Here, we put forward a novel technique capable of determining the OAM spectrum of light by a single measurement shot, which specifically applies to those fields that have been distorted. Experimentally, our technique only requires to interfere the perturbed light field with a reference field. From the resulting intensity pattern, the accurate OAM spectrum is determined in an all-digital way. We demonstrate our novel approach by numerical simulations and a proof-of-concept experiment employing a model ball lens as an exemplary disturbing object.
description: Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).
The new Milky Way satellites: alignment with the VPOS and predictions for proper motions and velocity dispersions
Creators: name: Pawlowski, Marcel S.
name: McGaugh, Stacy S.
name: Jerjen, Helmut
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The evidence that stellar systems surrounding the Milky Way (MW) are distributed in a Vast Polar Structure (VPOS) may be observationally biased by satellites detected in surveys of the northern sky. The recent discoveries of more than a dozen new systems in the southern hemisphere thus constitute a critical test of the VPOS phenomenon. We report that the new objects are located close to the original VPOS, with half of the sample having offsets less than 20 kpc. The positions of the new satellite galaxy candidates are so well aligned that the orientation of the revised best-fitting VPOS structure is preserved to within 9 degrees and the VPOS flattening is almost unchanged (31 kpc height). Interestingly, the shortest distance of the VPOS plane from the MW center is now only 2.5 kpc, indicating that the new discoveries balance out the VPOS at the Galactic center. The vast majority of the MW satellites are thus consistent with sharing a similar orbital plane as the Magellanic Clouds, confirming a hypothesis proposed by Kunkel & Demers and Lynden-Bell almost 40 years ago. We predict the absolute proper motions of the new objects assuming they orbit within the VPOS. Independent of the VPOS results we also predict the velocity dispersions of the new systems under three distinct assumptions: that they (i) are dark-matter-free star clusters obeying Newtonian dynamics, (ii) are dwarf satellites lying on empirical scaling relations of galaxies in dark matter halos, and (iii) obey MOND.
description: 17 pages, 6 figures, 5 tables. Updated to match version accepted for publication in MNRAS
Autoantibodies Define a Family of Proteins with Conserved Double-stranded RNA-binding Domains as Well as DNA Binding Activity
Creators: name: Satoh, Minoru
name: Reeves, Westley H.
name: Shaheen, Victoria M.
name: Yoshida, Hideo
name: Richards, Hanno B.
name: Okano, Tetsuroh
name: Shaw, Melody
name: Kao, Peter N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: Cellular responses to viral infection are signaled by double-stranded (ds) RNA, which is not found in substantial amounts in uninfected cells. Although cellular dsRNA-binding proteins have been described, their characterization is incomplete. We show that dsRNA-binding proteins are prominent autoantigens. Sera from B6 and B10.S mice with pristane-induced lupus and human autoimmune sera immunoprecipitated a novel set of 130-, 110-, 90-, 80-, and 45-kDa proteins. The proteins were all major cellular poly(IC)-binding factors. N-terminal amino acid sequences of p110 and p90 were identical and matched nuclear factor (NF) 90 and M phase phosphoprotein 4. p45 and p90 were identified as the NF45.NF90 complex, which binds the interleukin-2 promoter as well as certain highly structured viral RNAs. NF90.NF45 and M phase phosphoprotein 4 belong to a large group of proteins with conserved dsRNA-binding motifs. Besides binding dsRNA, NF90.NF45, p110, and p130 had single-stranded and dsDNA binding activity. Some sera contained autoantibodies whose binding was inhibited by poly(IC) but not single-stranded DNA or vice versa, suggesting that the DNA- and RNA-binding sites are different. These autoantibodies will be useful probes of the function of dsRNA-binding proteins. Their interaction with dsRNA, an immunological adjuvant, also could promote autoimmunity.
Flavonoidal alkaloids from the flowers of Chromolaena odorata (L.) R.M.King & H.Rob
Creators: name: Yang, Jian-Ni
name: Yi, Ji-Ling
name: Zou, Jing-Hua
name: Chen, Zhao-Xia
name: Chen, Guang-Ying
name: Hui, Yang
name: Sun, Zhen-Fan
name: Chen, Wen-Hao
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Virology

description: A pair of epimers of flavonoid alkaloids, with a pyrrolidone moiety, 2S,5′′R-eupodoratin A (1), 2S,5′′S-eupodoratin A (2), together with two known analogues, drahebephin A (3), drahebephin B (4), were isolated from the flowers of Chromolaena odorata (L.) R.M.King & H.Rob. Their structures were elucidated on the basis of HR-ESI-MS, 1D/2D NMR spectral analyses. The absolute configuration of compounds (1) and (2) was determined by its experimental and calculated electronic circular dichroism (ECD) spectra. All compounds were isolated from the Asteraceae family for the first time. The ABTS·+ scavenging activity of compound (4) reached 93.56% at a concentration of 0.5 mM, while the scavenging capacity of positive control Trolox was 55.94%. In addition, all compounds show moderate antimicrobial activity against Escherichia coli (ATCC, 337304), Staphylococcus aureus (ATCC, 337371) and Candida albicans (ATCC, 186382) with a MIC value of more than 50 µg/mL.
Cell-free Expression and Functional Reconstitution of Homo-oligomeric α7 Nicotinic Acetylcholine Receptors into Planar Lipid Bilayers
Creators: name: Lyford, Lisa K.
name: Rosenberg, Robert L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: The alpha7 nicotinic acetylcholine receptor (nAChR) is a ligand-gated ion channel that modulates neurotransmitter release in the central nervous system. We show here that functional, homo-oligomeric alpha7 nAChRs can be synthesized in vitro with a rabbit reticulocyte lysate translation system supplemented with endoplasmic reticulum microsomes, reconstituted into planar lipid bilayers, and evaluated using single-channel recording techniques. Because wild-type alpha7 nAChRs desensitize rapidly, we used a nondesensitizing form of the alpha7 receptor with mutations in the second transmembrane domain (S2'T and L9'T) to record channel activity in the continuous presence of agonist. Endoglycosidase H treatment of microsomes containing nascent alpha7 S2'T/L9'T nAChRs indicated that the receptors were glycosylated. A proteinase K protection assay revealed a 36-kDa fragment in the ER lumen, consistent with a large extracellular domain predicted by most topological models, indicating that the protein was folded integrally through the ER membrane. alpha7 S2'T/L9'T receptors reconstituted into planar lipid bilayers had a unitary conductance of approximately 50 pS, were highly selective for monovalent cations over Cl(-), were nonselective between K(+) and Na(+), and were blocked by alpha-bungarotoxin. This is the first demonstration that a functional ligand-gated ion channel can be synthesized using an in vitro expression system.
Qualitative inequalities for squared partial correlations of a Gaussian random vector
Creators: name: Chaudhuri, Sanjay
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistics Theory (math.ST)
subject: Applications (stat.AP)
subject: Computation (stat.CO)
subject: Methodology (stat.ME)
subject: Machine Learning (stat.ML)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: We describe various sets of conditional independence relationships, sufficient for qualitatively comparing non-vanishing squared partial correlations of a Gaussian random vector. These sufficient conditions are satisfied by several graphical Markov models. Rules for comparing degree of association among the vertices of such Gaussian graphical models are also developed. We apply these rules to compare conditional dependencies on Gaussian trees. In particular for trees, we show that such dependence can be completely characterized by the length of the paths joining the dependent vertices to each other and to the vertices conditioned on. We also apply our results to postulate rules for model selection for polytree models. Our rules apply to mutual information of Gaussian random vectors as well.
description: 21 pages, 13 figures
The Impact of Women’s Empowerment on the Corporate Environmental, Social, and Governance (ESG) Disclosure
Creators: name: Dempere, Juan
name: Abdalla, Shahira
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 350107
subject: Sustainability accounting and reporting
classificationCode: 350502
subject: Employment equity and diversity
classificationCode: 350702
subject: Corporate social responsibility
classificationCode: 350701
subject: Corporate governance

description: This research article examines the relationship between women’s empowerment and corporate ESG disclosure variables by analyzing 10,121 publicly traded companies listed worldwide with historical ESG data available in Bloomberg from 2016 to 2020. The paper seeks to answer whether corporate gender diversity directly affects companies’ ESG disclosure by using proprietary Bloomberg ESG disclosure scores and independent variables such as the female board and executive representation. Control variables, like the company’s return on equity, total debt ratio, and the natural logarithm of total assets as a proxy measurement of the firm’s size, are also included. Results provide evidence that policies that foster corporate gender diversity directly benefit from enhanced ESG-related disclosure, thus helping to trigger national dialogues about suitable corporate gender diversity strategies influencing firms’ ESG disclosure. This paper makes a unique contribution to the literature by being the first to analyze the effects of women’s empowerment on ESG disclosure using a globally representative sample. The evidence of the benefits of women’s empowerment associated with corporate ESG disclosure suggests that organizations with a more gender-diverse corporate board and executive team are more likely to have higher levels of ESG disclosure, as gender diversity increases the likelihood of organizational transparency and accountability, and can lead to improved corporate value. Governments should use this evidence to implement policies promoting women’s empowerment in the corporate world, ultimately leading to improved corporate ESG disclosure.
Three new isocoumarin analogues from an endolichenic fungus Aspergillus flavus CPCC 400810
Creators: name: Wang, Ren-Zhong
name: Su, Bing-Jie
name: Chen, Yu-Chuan
name: Xiao, Tong-Mei
name: Yan, Bi-Ying
name: Yu, Li-Yan
name: Si, Shu-Yi
name: Wu, De-Ling
name: Chen, Ming-Hua
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Five isocoumarin derivatives including three new compounds, aspermarolides A-C (1–3), and two known analogues, 8-methoxyldiaporthin (4) and diaporthin (5) were obtained from the culture extract of Aspergillus flavus CPCC 400810. The structures of these compounds were elucidated by spectroscopic methods. The double bond geometry of 1 and 2 were assigned by the coupling constants. The absolute configuration of 3 was determined by electronic circular dichroism experiment. All compounds showed no cytotoxic activities against the two human cancer cells HepG2 and Hela.
(1937) Bissel Harvey
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Cloning and Functional Expression of a Human Na + and Cl − -dependent Neutral and Cationic Amino Acid Transporter B 0+
Creators: name: Mager, Sela
name: Sloan, Jennifer L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: A Na(+)-dependent neutral and cationic amino acid transport system (B(0+)) plays an important role in many cells and tissues; however, the molecular basis for this transport system is still unknown. To identify new transporters, the expressed sequence tag database was queried, and cDNA fragments with sequence similarity to the Na(+)/Cl(-)-dependent neurotransmitter transporter family were identified. Based on these sequences, rapid amplification of cDNA ends of human mammary gland cDNA was used to obtain a cDNA of 4.5 kilobases (kb). The open reading frame encodes a 642-amino acid protein named amino acid transporter B(0+). Human ATB(0+) (hATB(0+)) is a novel member of the Na(+)/Cl(-)-dependent neurotransmitter transporter family with the highest sequence similarity to the glycine and proline transporters. Northern blot analysis identified transcripts of approximately 4.5 kb and approximately 2 kb in the lung. Another tissue survey suggests expression in the trachea, salivary gland, mammary gland, stomach, and pituitary gland. Electrophysiology and radiolabeled amino acid uptake measurements were used to functionally characterize the transporter expressed in Xenopus oocytes. hATB(0+) was found to transport both neutral and cationic amino acids, with the highest affinity for hydrophobic amino acids and the lowest affinity for proline. Amino acid transport was Na(+) and Cl(-)-dependent and was attenuated in the presence of 2-aminobicyclo-[2.2.1]-heptane-2-carboxylic acid, a system B(0+) inhibitor. These characteristics are consistent with system B(0+) amino acid transport. Thus, hATB(0+) is the first cloned B(0+) amino acid transporter.
title: Socialism Order of Worth and Analytical Adequacy Axiom
Creators: name: Schneijderberg, Christian
Publisher: name: Universität Kassel
Year: 2022
Subjects: subject: axiological sociology
subject: Orders of worth
subject: public and private health insurance
subject: sociology of conventions
subject: theory development
subject: 370
subject: Soziologie
subject: Wertphilosophie
subject: Konvention
subject: Private Krankenversicherung
subject: Gesetzliche Krankenversicherung
subject: Entwicklungstheorie

description: Gefördert im Rahmen des Projekts DEAL
Supplementary Information from Integrated human-virus metabolic stoichiometric modelling predicts host-based antiviral targets against Chikungunya, Dengue and Zika viruses.
Creators: name: Aller, Sean
name: Scott, Andrew
name: Mitali Sarkar-Tyson
name: Soyer, Orkun S.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Biochemistry
subject: 60114 Systems Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional analysis and methods, Supplementary tables, Supplementary figures, List of supplementary files and References
Diaporpyrone E, an undescribed α-pyrone from the endophytic fungus Diaporthe sp. CB10100
Creators: name: Pu, Hong
name: Peng, Dian
name: Tang, Genyun
name: Ma, Qingxian
name: Huang, Huaiyi
name: Zhong, Yani
name: Long, Jiayao
name: Huang, Xueshuang
name: Duan, Yanwen
name: Huang, Yong
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: An undescribed α-pyrone diaporpyrone E (1), and three known nucleotides, 5’-O-acetyl uridine (2), 5’-O-acetyl thymidine (3), and adenine (4), were identified from Diaporthe sp. CB10100, an endophytic fungus isolated from the medicinal plant Sinomenium acutum. The structure of 1 was determined by extensive analysis of its HRMS, 1D and 2D NMR spectroscopic data, as well as electronic circular dichroism calculations and comparison. The in vitro cytotoxic and antibacterial assays of 1 revealed that it has a 30.2% inhibitory effect on HepG2 cells at 50 μM, while no antibacterial activities against Staphylococcus aureus and Klebsiella pneumoniae at 64 μg/mL.
Influence of organic and inorganic fertilization on soil properties and water infiltration
Creators: name: Stehlík, M.
name: Czako, A.
name: Mayerová, M.
name: Madaras, M.
Publisher: name: Agronomy Research
Year: 2019
Subjects: soil quality
soil aggregate stability
infiltration
porosity
long-term field trial
article

description: Soil aggregate stability (SAS) belongs to the most important parameters determining the quality of soil and fertilizer influence on soil aggregation. We evaluated the relationship between SAS, hydro–physical soil properties and infiltration rates in three long–term field experiments founded in 1956 on different soils. Soil properties under three fertilization regimes–no fertilization, farmyard manure, farmyard manure and mineral fertilization–were evaluated at silty loam Chernozem, silty loam Phaeozem and sandy loam–loam Cambisol. A significant impact of fertilization on SAS was found, even though the differences in SAS were rather low. The lowest SAS was recorded at plots with manure and mineral fertilization (25.1%) compared with plots without fertilization (28.7%) and plots with manure–only fertilization (28.2%). The highest SAS (36.5%) and the highest semi–capillary porosity (SP; 11%) were observed at sandy loam–loam soil. Hydro–physical soil properties were more favourable at fertilized plots (SP 9.6% and bulk density ρb 1.31 g cm-3) compared with unfertilized ones (SP 8.8% and ρb 1.35 g cm-3). The lowest SP (8.32%) and the highest ρb (1.37 g cm-3) were recorded at Phaeozem, which corresponded with the lowest SAS (19.4%). Chernozem had similar soil texture to Phaeozem, but SAS (24.7%), SP (9%) and ρb (1.27 g cm-3) were more favourable. Despite the low level of statistical significance due to the large variation of infiltration measurements, a higher infiltration rate was recorded at fertilized plots (45 mm hour-1) compared to unfertilized ones (35 mm hour-1).
(1938) Adelaide Johanna Loftus Pickard
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.