cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Four new triterpene glucosides from Salacia cochinchinensis Lour
Creators: name: Gao, Lu
name: Duan, Li-Kun
name: Feng, Jin-E
name: Jiang, Yun-Tao
name: Gao, Jun
name: Fan, Jun-Ting
name: Dai, Rong
name: Jiang, Zhi-Yong
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Virology

description: Four new triterpene glucosides (1–4) were isolated from the 90% ethanol extract of Salacia cochinchinensis, together with five known compounds (5–9). The structures of the new compounds were elucidated by comprehensive spectroscopic analysis including HRESIMS, IR, 1 D and 2 D NMR analysis. All isolates were assayed for their α-glucosidase inhibitory activity. Compound 9 showed remarkable α-glucosidase inhibitory activity with an IC50 value of 0.31 μM, and the triterpene glycosides (1–5) exhibited moderate α-glucosidase inhibitory activity.
Turbo-charging Data Management Plans
Creators: name: Renner, Tom
Publisher: name: Zenodo
Year: 2020
Subjects: Data Management Plans
Open-Source
machine-actionable Data Management Plans
Open standards

description: Presentation given in the "Data Management Planning demonstrations" session at IDCC 2020 in Dublin, February 18th 2020. This demonstrates the implementation of machine-actionable Data Management Plans within Haplo research information management systems, using the RDA DMP Common Standard for Machine-actionable Data Management Plans.
Catalyst-free glycerol-mediated green synthesis of 5′-thioxospiro[indoline-3,3′-[1,2,4]triazolidin]-2-ones/spiro[indoline-3,3′-[1,2,4]triazolidine]-2,5′-diones
Creators: name: Tiwari, Jyoti
name: Saquib, Mohammad
name: Swastika Singh
name: Tufail, Fatima
name: Singh, Jaya
name: Jagdamba Singh
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: The development of new catalyst-free green and efficient protocol to access 5′-thioxospiro[indoline-3,3′-[1,2,4]triazolidin]-2-ones/spiro[indoline-3,3′-[1,2,4]triazolidine]-2,5′-diones, potential privileged scaffolds for drug discovery, is disclosed. Key feature of this methodology is the dual use of glycerol—a recyclable, bioorganic compound, as a solvent cum promoter. Other highlights include use of inexpensive reagents, mild reaction conditions, operational simplicity, short reaction time, no need for chromatographic purification, and high yields.
Mechanical Properties of Recycled tire wire and Glass Fiber Reinforced Concrete
Creators: name: Muleta, Moti
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2019
Subjects: Glass fibers, Recycled tire Fiber, Compressive strength, flexural strength, Split tensile strength, admixture

description: Concrete is a versatile construction material with various uses. It has poor tensile
 strength and good compressive strength mechanical properties. In past, an effort has been
 made to improve concrete mechanical properties by mixing with various foreign
 materials such as synthetic and natural fibers, steel wires and plastics. However, there is
 research gap in literature to study comparative use of recycled and new materials for
 improving concrete mechanical properties.
 This research work experimentally investigates use of new glass fibers and recycled tire
 fibers in 0.5%, 1% and 1.5% in weight mixes with concrete to study concrete mechanical
 properties performance gains such as compressive, flexural and split tensile strength
 properties.
 Experimental results indicated as compared to control plain concrete specimen, use of
 recycled steel fiber and glass fibers in concrete mix increased flexural property of
 concrete by 19.64% and 24.56% whereas split tensile strength of concrete is enhanced by
 8.15% and 12.02%, respectively. Similarly, compressive strength of concrete is improved
 by 5.34% and 7.87% respectively. Also, optimum blend percentage of recycled tire fiber
 and glass fiber for enhanced performance gains in concrete mechanical properties is one
 percent. Finally, use of recycled steel fibers and glass fibers in concrete exhibited
 similar concrete mechanical property performance gains however, recycled steel fibers
 has 78% direct cost reduction as compared to glass fibers. From the entire test, it is found
 that both recycled tire wire and glass fiber increases concretes mechanical properties.
Handlungsleitende Orientierungen von Praxislehrpersonengruppen an Partnerschulen der Pädagogischen Hochschule der Fachhochschule Nordwestschweiz (PH FHNW) im Kontext verschiedener Kooperationsformen
Creators: name: Oeschger, Thomas
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2017
Subjects: subject: 370 - Erziehung, Schul- und Bildungswesen

description: Handlungskompetenz stellt eine Basis für kooperatives Handeln dar. Sie wird als Zusammenspiel bewusster (expliziter) und unbewusster (impliziter) Wissensbestände betrachtet. Implizite Wissensbestände, auch konjunktives Wissen genannt, bestehen aus gemeinsam geteilten Erfahrungsräumen, welche Angehörigen von Gruppen, Generationen oder Milieus in atheoretischer Form verfügbar sind und als kollektiv-implizites Wissen ihre alltägliche Handlungspraxis mitbestimmen. Die vorliegende Masterarbeit untersucht, als empirische Forschungsarbeit, unter Einsatz der beiden qualitativen Verfahren Gruppendiskussion und Dokumentarische Methode solche impliziten, handlungsleitenden Orientierungen von Praxislehrpersonengruppen an Partnerschulen der Pädagogischen Hochschule der Fachhochschule Nordwestschweiz (PH FHNW) im Kontext ihres kooperativen Handelns in verschiedenen Kooperationsformen, um so einen Beitrag zu einem ganzheitlicheren Verständnis des Konstrukts Lehrerkooperation zu leisten. Die Ergebnisse aus dem Forschungsprozess zeigen die Bedeutsamkeit kollektiv-impliziter Wissensbestände für die Handlungskompetenz der Praxislehrpersonen im untersuchten Forschungsfeld und ermöglichen, nebst der ergänzenden Ausdeutung kooperativen Handelns, eine zusätzliche Perspektive auf die Konzeptionierung des Partnerschulmodells der PH FHNW sowie auf Professionalisierungsprozesse von Praxislehrpersonen.
Magnetically Recyclable Activated Carbon Prepared from Brewer's Spent Grain for Hexavalent Chromium Remediation
Creators: name: Belay   Getye Zafu
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Brewery spent grain, Hexavalent chromium, Magnetic Activated Carbon, Wastewater

description: This study is focused on the removal of hexavalent Cr (VI) heavy metal ion from
 wastewater using an adsorbent prepared from a brewer‘s spent grain. Activated
 carbon is synthesized from spent grain and then magnetized for better recycling. The
 crystal structure, molecular constituent, morphology and surface area of the asprepared AC and MAC were characterized using XRD, FTIR, SEM and BET
 characterization techniques. The removal efficiency of MAC for Cr (VI) from
 synthetic wastewater and real wastewater from Awash tannery effluent was examined.
 The BOD and COD of real wastewater were characterized before and after adsorption
 experiment. Factors such as change in pH of solution, adsorbent dose, initial
 concentration and contact time were optimized for the best Cr (VI) removal efficiency
 of the adsorbent. It was found that solution pH 2, initial concentration of 40 mg/l, a
 dosage of 5 g/l and a contact time of 30 min are optimum condition for the most
 efficient removal of chromium (VI). Almost 97.5% removal of Cr (VI) was achieved
 under the optimized conditions. The adsorption phenomena are consistent with
 pseudo-second order kinetics model, and the corresponding rate constant was found to
 be 11.47 × 10-2 g mg-1 min-1 with a high regression coefficient (R2 = 0.9954). The
 adsorption isotherm of Cr (VI) best fits with Temkin isotherm compared to other
 isotherm models. At the optimum conditions, adsorption process with MAC as an
 adsorbent showed a removal of 317.833+14 mg/l COD and 41.3+ 7.8 mg/l BOD from
 Awash tannery effluent. Recycling study using the optimized parameters showed
 promising recovery with only a slight fluctuation for the five consecutive cycles
Major Delay Factors and Their Impact on The Successful Project Completion: The Case of Oromia Health Bureau Hospitals
Creators: name: Kabeto, Abay
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Major/key factors of delay, Impacts of delay, Oromia Health Bureau, Hospitals Construction projects

description: Ethiopia’s Construction Sector were faced challenges of delay, which is one of the most common
 problems of construction projects performance. In order to minimize delays, one should only
 have been recognized their causes through serious investigations and need to take correction
 actions timely for successful performance of the projects. Delay of Projects can be due to a
 number of causing reasons which included to groups of the client, the contractor, the consultant,
 or external factors. As per desk review study conducted on Oromia Regional Health Bureau
 (ORHB) hospital project’s, the magnitude of delay was up to 396% of the contract time, which
 indicated that delay was a serious challenge to the performance of the bureau’s projects.
 The aim of the research was to identify key delay causing factors and their impacts as the case of
 ORHB hospitals construction projects and forwarded possible conclusions and recommendations
 based on the findings of the results. After an intensive literature and desk reviews mostly related
 to the field of factors and impacts of delay; a questionnaire survey was conducted to find the
 perception of major parties participating in the performance of the construction projects in the
 region. Accordingly, 60 major causes of delay which categorized into four groups and 20 impacts
 of delay were identified. The survey was carried out through a questionnaire from 42
 participants and collected and analyzed using Relative Importance Index (RII) for ranking. From
 the findings the 4 identified top key factors of delay out of 12 in ORHB were: Cash flow problems
 faced by the contractor, Contractor’s misuse of advance payment, Shortage or delay delivery of
 construction materials and equipment to the construction site by contractor and Instability
 (Security) problems of the region. The finding indicated that contractors were the major source of
 causes of delay. The paper further revealed that the most frequent occurring top 4 delay impacts
 were found Time and Cost overrun, Loss of revenue or profit, Cashflow problems and Escalation.
Level of Ochratoxin A In Coffee Stored At Different Condition
Creators: name: Kalkidan Adugna
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Coffee arabica L, A. niger, A. ochraceus, Ochratoxin A, storage conditions, European commission

description: Ochratoxin A (OTA) is a naturally occurring foodborne mycotoxin found in a wide variety of
 agricultural commodities worldwide, ranging from cereal grains to dried fruits to wine and
 coffee. OTA contamination of coffee is a worldwide problem. Coffee is a major Ethiopian export
 commodity generating about 25% of Ethiopia’s total export earnings. OTA is mainly produced in
 coffee by fungal species of Aspergillus ochraceus, Aspergillus carbonarius and Aspergillus
 westerdijkiae (section Circumdati). Post - harvest processes, one of the factor that affect coffee
 quality, has significant effects on coffee quality. During post- harvest process coffee may be
 infected with micro-organisms. OTA (Ochratoxin A) is a form of mycotoxin, produced as a
 metabolic product of Aspergillus ochraceus, Aspergillus. Carbonarius and strains of Aspergillus
 niger that degrade quality of coffee and causes disease to those who consumed it. OTA is
 efficiently absorbed from the gastrointestinal tract, mainly in the small intestine. Information
 from several species shows that it is spread via the blood, mainly to the kidneys, with lower
 concentrations found in liver, muscle, and fat. This study aims to assess the levels of OTA in
 green coffee in relation to different storage conditions. A total of 16 coffee storage conditions
 were created. The coffee samples were stored at different conditions (very low, low, medium,
 high and very high). OTA levels were analyzed using HPLC technique after extraction and
 filtration using an immunoaffinity column. Results were from 0.4550±0.24347 to 23.0600
 ±0.16971. From the total 16 conditions 10 samples contain high amount of OTA than other
 storage conditions. These were the sample stored at medium storage conditions (11%
 humidity,25oc temperature for 3 weeks) at these conditions the obtained result was above
 European commission limits. The rest 6 storage conditions were less than the European
 commission limits
"Auf die [...] grossen unnd kleinen Geygen / auch Lautten". Strategien zur Intavolierung von Vokalmusik in deutschen Lehrbüchern des frühen 16. Jahrhunderts
Creators: name: Lewon, Marc
Publisher: name: Schwabe
Year: 2020
Subjects: Großgeige
Laute
Gambe
Tabulatur
Martin Agricola
Hans Gerle
Sebastian Virdung

description: Die „deutsche“ Lautentabulatur wurde nicht nur zur Notation von Bearbeitungen für Laute, sondern auch für die identisch gestimmten „grossen Geigen“ verwendet. In den deutschen Musiklehrbüchern des frühen 16. Jahrhunderts wurden daher die verwandten Tabulaturen beider Instrumentenfamilien in Nachbarschaft zueinander besprochen. Gleich im ersten dieser Bücher (Musica getutscht, 1511) bemühte sich der Autor Sebastian Virdung darum, die Tabulaturschriften für Laien zugänglich zu machen. Was dabei in Bezug auf seine Lautenintavolierung wegen mangelnder Erfahrung noch im Ansatz hängen blieb, wurde von Hans Gerle gut 20 Jahre später didaktisch vorbildlich realisiert (Musica Teusch, 1532) und auf das Gambenconsort ausgeweitet. Kurz zuvor hatte Martin Agricola (Musica instrumentalis deudsch, 1529) versucht, die deutsche Tabulaturschrift durch ein neues, logischeres System zu ersetzen. Er kam damit aber zwei Jahrzehnte zu spät: Die deutsche Lautentabulatur war bereits so fest etabliert, dass sein Reformversuch zur Fußnote der Musikgeschichte wurde.
Indium triflate and ionic liquid mediated Friedländer synthesis of 2-acylquinolines
Creators: name: Satheeshkumar, Rajendran
name: Sayin, Koray
name: Kaminsky, Werner
name: Prasad, Karnam Jayarampillai Rajendra
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Friedländer synthesis of 2-acylquinolines from the reaction of symmetrical and unsymmetrical 1,2-diketones with 2-aminoarylketones in the presence of indium triflate (In(OTf)3) and ionic liquid give quantitative yields. Once the reaction was completed, the catalysts can be recovered and subsequently run for next cycles. Results obtained from theoretical studies has more strengthened by FT-IR, FT-NMR chemical shifts and structural parameters which were attained with B3LYP/6-31G(d,p) level of theory and the related results were demonstrated with the experimental interpretations.
A Web-Based Self-help Intervention for Coping With the Loss of a Partner. Protocol for Randomized Controlled Trials in 3 Countries
Creators: name: Brodbeck, Jeannette
name: Bilreiro Jacinto Braga, Ana Sofia
name: Gouveia, Afonso
name: Mendonça, Nuno
name: Madörin, Sarah
name: Brandl, Lea
name: Schokking, Lotte
name: Rodrigues, Ana Maria
name: Gonçalves, Judite
name: Mooser, Bettina
name: Marques, Marta M
name: Isaac, Joana
name: Nogueira, Vasco
name: Matos Pires, Ana
name: Van Velsen, Lex
Publisher: name: JMIR Publications
Year: 2022
Subjects: subject: bereavement
subject: cognitive behavioral therapy
subject: CBT
subject: cost-effectiveness
subject: electronic mental health
subject: grief
subject: Technology acceptance
subject: 300 - Sozialwissenschaften

description: This study aims to evaluate the clinical efficacy and acceptance of a web-based self-help intervention to support the grief process of older adults who have lost their partner. It will compare the outcomes, adherence, and working alliance in a standardized format with those in a self-tailored delivery format and investigate the effects of age, time since loss, and severityof grief at baseline as predictors. Focus groups to understand user experience and a cost-effectiveness analysis will complementthe study.
Live Virtual Machine Migration Based On Memory Compression & Smart Termination Criteria
Creators: name: Gebremichael  Gebru
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Live Migration, Smart termination, Memory Compression, Pre-copy, Virtualization and Cloud Computing

description: In this thesis, researchers have studied the area of virtualization. The focus has been on the sub-area
 live migration, a technique that allows seamless migration of a virtual machine from one physical
 machine to another physical machine. Live virtual machine migration refers to the process of moving a
 running virtual machine or application between different physical machines without disconnecting
 the client or application. Memory, storage, and network connectivity of the virtual machine are
 transferred from the original guest machine to the destination. Live virtual machine migration is an
 attractive technique used to utilize resources in cloud-based data centers through load balancing, fault
 tolerance, and system maintenance. The performance of live VM migration is measured using different
 parameters such as total migration time, downtime, and total memory page transferred. This study has
 proposed a solution to the problem of a huge number of memory pages are being dirtied during the
 iterative phase of pre-copy live VM migration. A live migration based on combined memory
 compression and smart termination criteria is proposed it operate as follows: before memory pages are
 being transferred compression, process is undertaken on those pages. While memory pages are
 transferred from source host to destination host iteratively, a smart termination criterion is used as a
 control unit and, when and how the iterative phase of pre-copy will be executed is examined using this
 controlling system. The memory page compression process decreases the size of each transferred
 memory page which helps to decrease the network bandwidth usage for memory transfer and this
 directly helps to decrease a memory page being dirtied. The smart termination criteria help to decrease
 the number of dirtied memory pages being transferred which directly decreases the downtime of live VM
 migration. The experiment researchers have conducted shows that the proposed system has decreased
 33.52% of total migration time, 46.63% of downtime, and 78.6% of cut down on the total memory page
 transferred from pre-copy live virtual machine migration. When researchers compare the proposed
 system to the work of MECOM (memory compression based live migration) an average of 22.05% on
 total migration time, 26.86% on downtime and 33.04% on total memory page transferred has been
 decreased
Features of the legal regulation of a sports contract with woman professional athletes
Creators: name: Musaev Elbek Tayufovich
Publisher: name: Zenodo
Year: 2024

description: Annotation

The article touches upon the peculiarities of the terms of a sports contract concluded with a professional athlete, and analyzes the problems of legal regulation of such conditions. Attention is paid to the legal acts governing these relations, as well as the conditions on which the parties agree when concluding a professional contract for an athlete. It is noted that sports contracts have a complex legal nature. They interact with the norms of both civil and labor law. It is concluded that in a sports contract it is necessary to exclude some of the athlete’s responsibilities related to the limitation of her personal rights.

Keywords: sport, law, sports relations, sports contract, contract terms, professional athlete, national legislation.
Huldrych Zwingli, ein Schaffhauser Ex-Abt und die Groß Geigen. Zwei Schweizer Quellen für Streichinstrumenten-Ensembles um 1528/1529
Creators: name: Papiro, Martina
Publisher: name: Schwabe
Year: 2018
Subjects: Viola da gamba
Musikikonographie

description: Der Beitrag untersucht zwei bisher für die Geschichte früher Streichinstrumente unbeachtete Quellen: Einen Brief und ein Glasgemälde aus dem Kontext der Schweizer Reformation, die ein Ensemble aus Groß Geigen erwähnen bzw. zeigen.
A facile convergent route to indoloquinolines
Creators: name: Kadam, Hari K.
name: Deesha D. Malik
name: Lalitprabha Salgaonkar
name: Ketan Mandrekar
name: Tilve, Santosh G.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: A convergent route to indoloquinolines is developed via Aldol condensation. This two step method utilizes commercially available 2-oxoindole and o-nitrobenzaldehyde as starting materials. Chromatography-free method is accomplished for preparing several derivatives of indoloquinolines with desirable aromatic substitutions.
Landslide Susceptibility Mapping Using GIS – Based Information Value & Frequency Ration Methods in Gindeberet Area ,wes Shewa zone Oromia Regional
Creators: name: Alembante Genene  Bekele
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Frequency Ratio, GIS, Gindeberet woreda, Information value, Landslide Susceptibility map

description: Gindeberet is found in west Shewa, central Ethiopia and 182km far from the capital city Addis
 Ababa. The area is highly susceptible to active surface processes and landslide activities due to
 the presence of sharp ridges, cliffs, rugged slope faces, steep scarps, deep gorges and valleys.
 The main objective of the study was to identify and evaluate the causative factors and to prepare
 the landslide susceptibility map of the study area. In this study, two bivariate statistical models:
 the Information value and the Frequency ratio were used to produce landslide susceptibility maps
 for the study area. At the first stage, active, reactivated and passive landslides scarps were
 identified using Google earth image interpretation and extensive field survey and the landslide
 inventory map of the study area was prepared in ArcGIS. A total of 580 landslide polygons were
 randomly separated into two datasets: 460 landslides (80%) for modeling and 116 landslides
 (20%) for validation. Then, eight (8) landslide conditioning factors: Slope, Aspect, curvature,
 distance from stream, distance from lineaments, Lithology, rainfall and land cover/use were
 considered for modeling. Those conditioning factors are combined with a training dataset using
 GIS tools to generate the landslide susceptibility maps of the study area. Then, the area was
 divided into five LSZ very low, low, moderate, high and very high zones. Landslide
 susceptibility map prepared using IV model showed that from the total area 7.1%, 22.4%, 23.9%,
 29.5%, and 17.1% of the area covered by very low, low, moderate, high and very high classes
 respectively. Landslide susceptibility map prepared using FR model showed that from the total
 area 26.1%, 27.8%, 26.7%, 12.7%, and 6.7% of the area covered by very low, low, moderate,
 high and very high classes respectively. The performances of both models were valuated using
 the Area under curve (AUC) of the receiver operating characteristic (ROC) and landslide density
 index (LDI) methods. The validation result using the ROC curve for information value and
 frequency ratio models were a success rate of 0.836 and 0.835 respectively, and a predictive rate
 of 0.817 and 0.818, respectively. Based on the AUC evaluation, the landslide susceptibility maps
 produced by both models were very similar. The resultant maps would be useful for general land
 use planning.
Landslide Susceptibility Mapping and Slope Stability Analysis Using Statistical and Deterministic Methods in Kabi-Gebro Area, Central Ethiopian
Creators: name: Nega Getachew
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Landslide Susceptibility Map, Weights of Evidence, Deterministic Methods, Kabi-Gebro, Northwestern Ethiopian Highland.

description: Kabi-Gebro area is located within the Abay Basin at Dera District of North Shewa Zone
 in the Central highland of Ethiopia and it is about 320 Km from Addis Ababa. The area
 characterized by rugged topography, intense rainfall, active erosion and is highly
 cultivated. Currently, various types of landslides are creating serious challenges in road
 construction, farmlands and hence the likelihood of the people in this area. Active
 landslides in this area damaged the gravel road, houses and agricultural land. The main
 objective of this research is to prepare the landslide susceptibility map and to perform
 slope stability analysis along the selected road section. Landslide susceptibility map
 was prepared using GIS- based Weights of Evidence model and some of the critically
 failed slope sections along the road were evaluated using deterministic models. Based
 on detailed field assessment and Google Earth image interpretation, 514 landslide
 locations were identified and classified as training landslide (80%) and validation
 landslide (20%). Nine landslide causative factors: slope, curvature, aspect, lithology,
 rainfall, land use, distance to stream, lineament and spring were overlaid with the
 training landslide. The landslide susceptibility maps were prepared by adding the
 weight of contrast value of nine factors using rater calculation in the spatial analyst tool
 of ArcGIS. Finally, the landslide susceptibility map was validated using the success
 rate and predictive rate curves. The result revealed a success rate of 82.2% and a
 predictive rate of 83%. In addition, the stability conditions of rock slopes were
 evaluated using RMR, kinematic and deterministic approaches. The geotechnical
 properties of rocks and soils were determined from in-situ and laboratory tests. The
 factor of safety for selected slopes under different conditions were calculated using
 Slide, Rocplane and Swedge software for soil, plane and wedge failures respectively.
 From RMR values in selected slope sections, the rock masses were categorized into fair
 and good quality. The critical soil slope sections were classified into CH and CL soil
 types. The kinematic analysis resulted in three planar and three wedge modes of failures
 were further evaluated using deterministic approaches. The results of all the slope
 stability assessment showed that all slopes were unstable under the worst condition and
 some of them under moderately saturated. This study recommended appropriate
 mitigation or corrective measures in order to lessen the impact of landslide in the area.
Psychological Distance in German and English Brand Language of Eight International Brands
Creators: name: Griesser, Simone
Publisher: name: Zurich University of Applied Sciences ZHAW & University of Zurich at http://ceur-ws.org
Year: 2020
Subjects: subject: language concreteness
subject: brand communication
subject: Twitter
subject: language analysis
subject: brand management
subject: computational method
subject: psychological distance
subject: 330 - Wirtschaft
subject: 380 - Handel, Kommunikation, Verkehr
subject: 400 - Sprache, Linguistik

description: Language offers additional insights to sentiment and content. The same content can be described with psychologically close or distant language. According to the Construal-Level Theory (Trope & Liberman, 2010), psychological distance influences decision-making. Seven of the eight examined brands psychologically approach customers with their English brand language but psychologically distance themselves from customers with their German brand language on Twitter. Only one brand shows no psychological distance difference between their English and German brand language on Twitter. Implications on decision-making and brand positioning are discussed.
Facile synthesis of cyclopentapeptide, cyclo[Arg(NO2)-Gly-Asp(OBn)-D-Phe-Lys(Fmoc)], and its application in synthesis of integrin-targeting anticancer conjugate
Creators: name: Da-You Ma
name: Zhong, Tao
name: Long-Long Wang
name: Liu, Li-Jun
name: Ying-Xiong Wang
name: Su-You Liu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 60506 Virology

description: An efficient approach for integrin-targeting cRGDfK conjugate synthesis has been developed using a new protected cyclopentapeptide, cR(NO2)GD(Bn)fK(Fmoc), as the key intermediate. cR(NO2)GD(Bn)fK(Fmoc) was conveniently prepared in high yield. The Fmoc group of this cyclopentapeptide was selectively removed under mild conditions which makes it an ideal intermediate for cRGDfK conjugate synthesis as was well demonstrated in this paper by the synthesis of cRGDfK chlorambucil conjugate.
title: Intracellular Imaging with Genetically Encoded RNA-Based Molecular Sensors
Creators: name: Sun, Zhining
name: Nguyen, Tony
name: McAuliffe, Kathleen
name: You, Mingxu
Publisher: name: University of Massachusetts Amherst
Year: 2019
Subjects: subject: RNA aptamers; biosensors
subject: live-cell imaging
subject: fluorogenic RNA
subject: riboswitch
subject: ribozyme

description: Abstract Genetically encodable sensors have been widely used in the detection of intracellular molecules ranging from metal ions and metabolites to nucleic acids and proteins. These biosensors are capable of monitoring in real-time the cellular levels, locations, and cell-to-cell variations of the target compounds in living systems. Traditionally, the majority of these sensors have been developed based on fluorescent proteins. As an exciting alternative, genetically encoded RNA-based molecular sensors (GERMS) have emerged over the past few years for the intracellular imaging and detection of various biological targets. In view of their ability for the general detection of a wide range of target analytes, and the modular and simple design principle, GERMS are becoming a popular choice for intracellular analysis. In this review, we summarize different design principles of GERMS based on various RNA recognition modules, transducer modules, and reporting systems. Some recent advances in the application of GERMS for intracellular imaging are also discussed. With further improvement in biostability, sensitivity, and robustness, GERMS can potentially be widely used in cell biology and biotechnology.
Additional file 1 of Target residence of Cas9-sgRNA influences DNA double-strand break repair pathway choices in CRISPR/Cas9 genome editing
Creators: name: Liu, Si-Cheng
name: Feng, Yi-Li
name: Sun, Xiu-Na
name: Chen, Ruo-Dan
name: Liu, Qian
name: Xiao, Jing-Jing
name: Zhang, Jin-Na
name: Huang, Zhi-Cheng
name: Xiang, Ji-Feng
name: Chen, Guo-Qiao
name: Yang, Yi
name: Lou, Chao
name: Li, Hao-Dan
name: Cai, Zhen
name: Xu, Shi-Ming
name: Lin, Hui
name: Xie, An-Yong
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Additional file 1: Figure S1. Generation of DNA-PKcs–/– and Ku80–/– HDR reporter mESC clones. Figure S2. The effect of DNA-PKcs inhibition on the patterns of Cas9-induced NHEJ analyzed by targeted PCR amplicon Illumina sequencing. Figure S3. The effect of DNA-PKcs inhibition on the patterns of Cas9-induced NHEJ at the Cola1 and Rosa26 locus. Figure S4. Effect of DNA-PKcs inactivation on I-SceI-induced mutNHEJ. Figure S5. Sequences of mismatched or truncated sgRNAs used for weakening target interaction of Cas9-sgRNA. Figure S6. Effect of DNA-PKcs inhibition on SpCas9-mediated gene knockout (KO) at GFP gene. Figure S7. Replication locally disengages c-NHEJ at Cas9-induced DSBs. Figure S8. Analysis of palindromic sister chromatid ligation. Figure S9. Junctions of palindromic sister chromatid NHEJ products.
Organisationsdiagnose beim Drahtesel
Creators: name: Kopp, Ruben
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2015

description: Standardisierte Organisationsdiagnosen / Mitarbeitendenbefragungen können aufgrund der angestrebten Vergleichbarkeit der Ergebnisse nur begrenzt auf spezifische Eigenheiten von Organisationen eingehen. Die Geschäftsleitung des Drahtesels beauftragte den Autor dieser Bachelor-Thesis daher mit der Konzipierung einer spezifisch am Drahtesel orientierten Befragung. Die Partizipation der Mitarbeitenden am Entstehungsprozess ist dabei zentral, mit dem Ziel, Themen zu eruieren, die aus Sicht der Zielgruppe in die Befragung gehören. Aus zwei mit Mitarbeitenden durchgeführten Workshops werden Themen und Items abgeleitet. Diese werden im Format der Likert-Skala und auf Basis einschlägiger Literatur zu einer Fragebatterie zusammengestellt. Der erweiterte Pretest gibt den Mitarbeitenden die Gelegenheit, sich zu den ausgewählten Themen und Items zu äussern. Als Ergebnis geht eine Befragung mit insgesamt 44 Items in 7 Ober- und 25 Unter-Kategorien hervor. Weiter werden die Risiken und Chancen des partizipativen Vorgehens erörtert und ein Ausblick auf die Durchführung der Befragung rundet die Thesis ab.
Catalyst free glycerol mediated green synthesis of 5′-thioxospiro[indoline-3,3′-[1,2,4]triazolidin]-2-ones/spiro[indoline-3,3′-[1,2,4]triazolidine]-2,5′-diones
Creators: name: Tiwari, Jyoti
name: Saquib, Mohammad
name: Swastika Singh
name: Tufail, Fatima
name: Singh, Jaya
name: Jagdamba Singh
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: The development of a new catalyst free green and efficient protocol to access 5′-thioxospiro[indoline-3,3′-[1,2,4]triazolidin]-2-ones/spiro[indoline-3,3′-[1,2,4]triazolidine]-2,5′-diones, potential privileged scaffolds for drug discovery, is disclosed. Key feature of this methodology is the dual use of glycerol - a recyclable, bioorganic compound, as a solvent cum promoter. Other highlights include use of inexpensive reagents, mild reaction conditions, operational simplicity, short reaction time, no need for chromatographic purification and high yields.
Laboratory investigation on The Rheological Property of Bitumen Emulsion ( Superpave Performance Based Test Method)
Creators: name: Samrawit Teklehaimanot
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Bitumen Emulsions, Dynamic Shear Rheometer (DSR), Rolling Thin Film Oven (RTFO), Aging

description: Nowadays, flexible pavements are constructed numerously. As one of the materials used
 for this pavement type, bitumen emulsions are used to construct a surface treatment road
 and as a tack coat to bind the binder course and wear course of the asphalt. Nevertheless,
 the performances of the roads are not as adequate as expected. Different reasons are
 given for these failures, but the research on the behavior of the binder (bitumen emulsion)
 is not that much, especially in our country, Ethiopia. The study of asphalt emulsion needs
 a fundamental knowledge of the physical and chemical properties of the emulsion.
 Therefore, using a predictive estimate of the rheological properties of the bituminous
 materials accurately would be useful for the pavement design. Accordingly, this study has
 focused on three curing methods that are selected to get the residue of the bitumen
 emulsion. The first is the ASTM D7497 method (48 hours curing method), the second
 method is ASTM D6944 (3 hours curing method under the temperature of 1630C), and the
 RTFO aging process. Using the application of a Dynamic Shear Rheometer, the
 rheological characteristics of the bitumen emulsion is studied. Conventional tests of
 Penetration, Ductility and Viscosity are also performed. The Amplitude Sweep Test
 (AST), which is used to get the minimum strain to determine the Linear Visco Elastic
 Range, the Frequency Sweep Test (FST) which is used to study the rheological property
 of the Visco-elastic material by developing master curves, the Performance Grading
 determination test which has the advantage to grade the binder based on its performance
 and Multiple Stress Creep Recovery Test (MSCR – Test), which is used to characterize
 better the binders possibility for permanent deformation, are performed. Test
 temperatures of 10.00C, 21.10C, 37.80C, and 54.40C were selected for the AST and FST
 tests and the high testing temperature was used for PG and MSCR tests. From the AST
 test a minimum strain value of 0.611 is obtained and used for the FST test. And from the
 MSCR test a value of 0.7689, Jnr at 3.2kPa at 520C is found. From the test results, it is
 understood that both the ASTM D7497 and RTFO Aged binders have a better
 performance than the ASTM D6944 method. In general, it is observed that the strength
 and overall performance of the binder are highly affected by temperature, loading, and
 curing method used. And also, it can be said that this method has better characterize the
 behavior of the binder than the conventional tests
Sovereign risk and the pricing of corporate credit default swaps
Creators: name: Härri, Matthias
name: Morkoetter, Stefan
name: Westerfeld, Simone
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2015
Subjects: subject: 330 - Wirtschaft

description: Investigation about the impact of sovereign risk on the pricing of corporate credit risk.
TBP - Molecule of the Month December 2011 [Archived version]
Creators: name: Cotton, Simon
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for December 2011 about 2,4,6-tribromophenol. It is a pdf archive version of the HTML webpage.
Grenzgang
Creators: name: (:Unkn) Unknown
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2020
Subjects: Walking
Artistic Research
Art Education
TriRegio Basel
Performance
Border
Reseach through music
Spatial Perception
Strollology
künstlerische Forschung
Promenadologie
Dokumentation
Grenze
Raumwahrnehmung

description: Dieser Raum wird im Projekt Grenzgang als ein Sonderfall betrachtet, um einen konkreten, gleichwohl aber nicht von seinen Abmessungen her definierten Raum auf seine raumbildenden Qualitäten hin zu untersuchen: Wie bildet sich für uns Raum aus? Welche Bedingungen fliessen in unser Verständnis von Raum ein? Und wie lässt sich dieses Verständnis produktiv für den bewussten Umgang mit dem vorhandenen Raum einbringen? Damit zielt das Projekt auf die Erforschung der Bedingungen, Konsequenzen und möglicher Potentiale unserer Raumerfahrung. Auf einer methodologischen Ebene erbringt Grenzgang einen Diskussionsbeitrag zur künstlerischen Forschung: das Projekt erprobt in seiner interdisziplinären Anlage die Beziehung der Erkenntnisweisen von künstlerischer Forschung und Kunstvermittlung. Forschungsteam und Vorgehen Das Projekt Grenzgang ist als Teamforschung angelegt, die die unterschiedlichen Arbeits- und Sichtweisen der beteiligten Disziplinen (Kunst, Musik, Kunstgeschichte, Kunstvermittlung, Künstlerische Forschung) gegenüberstellt und miteinander verknüpft. Gemeinsame Basis bilden an die Promenadologie angelehnte Spaziergänge entlang der Grenzlinie, die in künstlerischen Raumprotokollen dem gesamten Team zur Verfügung gestellt werden. Ausgewertet wird das Datenmaterial der Raumprotokolle in einer methodischen Triangulation als Verknüpfung unterschiedlicher Arbeitsweisen der Raumwahrnehmung. Aus der Musik durch ein Forschungsinterface, das unterschiedliche Quellen wie Videos, Bilder, Töne, Text und Musik in der INTERPRETATION verbinden kann. Künstlerische und kunstvermittelnde Auswertungen setzen die Daten in INSTALLATION und PERFORMANCE miteinander in Beziehung. Begleitet wird das Projekt durch Forschungsworkshops mit internationalen Experten aus den Kulturwissenschaften, Kunstpädagogik und Kunstvermittlung, Kunst und Künstlerischer Forschung, Experimentelle Musik, Soziologie und Stadtforschung.
Additional file 1 of Reducing the risk of Plasmodium vivax after falciparum infections in co-endemic areas—a randomized controlled trial (PRIMA)
Creators: name: Thriemer, Kamala
name: Degaga, Tamiru Shibru
name: Christian, Michael
name: Alam, Mohammad Shafiul
name: Ley, Benedikt
name: Hossain, Mohammad Sharif
name: Kibria, Mohammad Golam
name: Tego, Tedla Teferi
name: Abate, Dagimawie Tadesse
name: Weston, Sophie
name: Karahalios, Amalia
name: Rajasekhar, Megha
name: Simpson, Julie A.
name: Rumaseb, Angela
name: Mnjala, Hellen
name: Lee, Grant
name: Anose, Rodas Temesgen
name: Kidane, Fitsum Getahun
name: Woyessa, Adugna
name: Baird, Kevin
name: Sutanto, Inge
name: Hailu, Asrat
name: Price, Ric N.
Publisher: name: figshare
Year: 2022
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 1. Rationale for study.
Simple one-pot multicomponent approach to polyfunctionalized 2-amino-1-methyl-6-(methylthio)-5-nitro-4-aryl-1,4-dihydropyridine-3-carbonitriles
Creators: name: Kushvar Hajiyeva
name: Ismiev, Arif
name: Franz, Max
name: Schmidtmann, Marc
name: Martens, Jürgen
name: Maharramov, Abel
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Plant Biology

description: A series of polyfunctionalized 2-amino-1-methyl-6-(methylthio)-5-nitro-4-aryl-1,4-dihydropyridine-3-carbonitriles have been prepared using a multicomponent condensation reaction between aromatic aldehydes, malononitrile, and (Z) N-methyl-1-(methylthio)-2-nitroethenamine in the presence of Et3N in acetonitrile.
Isolation & Characterization of Pectinase Producing Bactria from Avocado Peel Wastes for Juice Clarification
Creators: name: Setegn Haile Temare
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Clarification, Enzyme, Fruit juice, Pectin, Pectinase, Pectinase activity

description: Bacterial species produce pectinase enzyme and the applications of this enzyme have
 been used in various biotechnological industries for degradation and removal of pectin
 polysaccharide materials. The main aim of this study was to isolate, screen and characterize
 pectinase producing bacteria from avocado peel wastes for potential use in fruit juice extraction
 and clarification processing. Four different bacteria were isolated from the avocado peel waste
 sample. The isolated bacterias screened using in primary screening method on pectin agar
 medium. The primary screening has confirmed that only three bacterial isolates, denoted as W3,
 Y31 and R5 were observed as pectinase producers and they were further screened by secondary
 screening method for pectinase production. Two bacterial isolates W3 and R5 shown higher
 pectinase activities in 24 hours as compared to isolate Y31 and the highest pectinase producing
 bacterial isolates were characterized by morphological, and biochemical methods and confirmed
 to belong to the genus of the species Bacillus (W3) and Serratia (R5). Further validation of
 identification and evolutionary history of the two potential isolates was made using 16S rRNA
 sequencing and constructed phylogenetic trees confirmed that the strains W3 and R5 are related
 to Lysinibacillus macroides and Serratia marcescens respectively. One of bacterial strains
 Serratia marcescens (R5) was selected for detailed analysis of pectinase production and
 application in fruit juice clarification. Consequently, the maximum crude pectinase enzyme
 activity from Serratia marcescens (R5) was observed to be 8.91± 0.23 in 72 hours incubation
 time at an optimal temperature of 35oC, pH 8 using 1% of pectin substrate as carbon sources.
 The pectinase enzyme from this bacterial strain was partially purified using ammonium sulphate
 followed by dialysis. The amounts of total protein content of the crude pectinase, purified
 pectinase with ammonium sulphate, and dialyzed pectinase obtained were 57.45mg, 20.1mg and
 10.mg respectively. The specific enzyme activity of the partially purified pectinase (47.32U/mg)
 was high compared to the crude pectinase (33.68U/mg). Finally, both crude and partially
 purified pectinase were applied to apple, lemon, and mango fruit juice processing to observe
 percentage yield and clarity of each fruit juice. Accordingly, the partially purified pectinase
 enzyme showed the highest percentage yield and clarity of 96.67% and 95.82% for lemon fruit
 juice processing
A simple one-pot multicomponent approach to polyfunctionalized 2-amino-1-methyl-6-(methylthio)-5-nitro-4-aryl-1,4-dihydropyridine-3-carbonitriles
Creators: name: Kushvar Hajiyeva
name: Ismiev, Arif
name: Franz, Max
name: Schmidtmann, Marc
name: Martens, Jürgen
name: Maharramov, Abel
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Plant Biology

description: A series of polyfunctionalized 2-amino-1-methyl-6-(methylthio)-5-nitro-4-aryl-1,4-dihydropyridine-3-carbonitriles have been prepared by using a multicompo-nent condensation reaction between aromatic aldehydes, malononitrile and (Z) N-methyl-1-(methylthio)-2-nitroethenamine in the presence of Et3N in acetonitrile.