cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
New Jersey 1980 State Water Quality Inventory
Creators: name: No Name Supplied
Publisher: name: State of New Jersey Department of Environmental Protection
Year: 1980

description: This report addresses the quality of New Jersey's water and includes an introduction and summary of methods, summaries of water quality data and water quality problems, the capital costs of achieving 1983 goals of the Clean Water Act Amendments, an analysis of the occurrence and distribution of toxic substances in New Jersey's surface and groundwaters, an inventory water quality in 27 New Jersey waterways, a report on shellfish harvest, a report on toxic materials spills and fish kills, and a report on the Lakes Management Program.
Legousia scabra Gamisans
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Legousia
Legousia scabra

description: Legousia scabra (Lowe) Gamisans
− Secteur San Petrone, entre Ponte Leccia et Merusaglia, crête entre Cima Pedani et Punta di Querceta Tonda, versant SW, arête calcaire, 800- 650 m, 6.6.201 2, Bioulez, P. & J. Gamisans s.n. (Hb. privé Gamisans).
Cette espèce, indiquée comme très rare en Corse (RR) par JEANMONOD & GAMISANS (Fl. Corsica (ed. 2): 171, 2013), n’était signalée dans le San Petrone qu’à l’écaille de Campettine près de Corte et entre San Nicolao et Cervione (DESCHÂTRES et al., Candollea 46: 199, 1991 et DUTARTRE et al., Candollea 48: 547, 1991). Signalée désormais de 8 stations des secteurs de San Petrone, Rotondu, Ospedale-Cagna et Bonifacio, son statut de fréquence doit désormais être plutôt considéré comme rare (R).
description: Published as part of Jeanmonod, Daniel, 2015, Notes à la flore de Corse, XXV, pp. 109-140 in Candollea 70 (1) on page 126, DOI: 10.15553/c2015v701a10, http://zenodo.org/record/5720895
New Jersey 1976 State Water Quality Inventory
Creators: name: No Name Supplied
Publisher: name: State of New Jersey Department of Environmental Protection
Year: 1977

description: This report includes a compilation of data collected by various Federal, State and local agencies and represents the best assessment to date of existing water quality in New Jersey.  Graphically presented data indicates water quality improvement and degradation which occurred during the past five years.  Anticipated changes resulting from Departmental programs and activities are also identified in the report.  Attainability of the 1983 fishable and swimable goals of the Act is assessed and resources for achieving these goals are also considered.
State of New Jersey Water Quality Inventory Section 305(b) Report, 1975
Creators: name: No Name Supplied
Publisher: name: State of New Jersey Department of Environmental Protection
Year: 1975

description: The report is organized to answer five questions: 1.) What is the quality of New Jersey waters today, particularly in our priority basins and priority segments, and where and how has the program made a difference in the last 5 years? 2.) What uses of the water are possible today and what uses will New Jersey waters support when the provisions of the Act are implemented to the extent technically or economically attainable? 3.) In what places will these future intended uses differ from the goals of fishable, swimmable waters intended in the Act? 4.) What will it cost to achieve these future intended uses? 5.) Where and to what extent are nonpoint sources going to prevent our meeting intended uses? How can they be controlled, and how much would it cost?
Water Quality Inventory, Annual Statewide Assessment (Condensed)
Creators: name: No Name Supplied
Publisher: name: State of New Jersey Department of Environmental Protection
Year: 1975

description: This is the condensed version of the 1975 State of New Jersey Water Quality Inventory Section 305(b) Report. The report is organized to answer five questions: 1.) What is the quality of New Jersey waters today, particularly in our priority basins and priority segments, and where and how has the program made a difference in the last 5 years? 2.) What uses of the water are possible today and what uses will New Jersey waters support when the provisions of the Act are implemented to the extent technically or economically attainable? 3.) In what places will these future intended uses differ from the goals of fishable, swimmable waters intended in the Act? 4.) What will it cost to achieve these future intended uses? 5.) Where and to what extent are nonpoint sources going to prevent our meeting intended uses? How can they be controlled, and how much would it cost?
Special Report 38: Magnitude and Frequency of Floods in New Jersey with Effects of Urbanization
Creators: name: No Name Supplied
Publisher: name: State of New Jersey: Department of Environmental Protection, Division of Water Resources
Year: 1974

description: Special Report 38 of the State of New Jersey, Department of Environmental Protection, Division of Water Resources uses mathematical and graphical relations to estimate flood-peak magnitudes having selected recurrence intervals ranging from 2 to 100 years for drainage basins larger than one square mile with various degrees of existing or projected urban and suburban development.
Legousia speculum-veneris (L.) Chaix
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Legousia
Legousia speculum-Veneris

description: Legousia speculum-veneris (L.) Chaix
− Secteur Rotondu, commune de Guagno, forêt territoriale de Guagno, piste la plus au Nord, à l’extrémité de la piste dans le haut vallon du ruisseau de l’Albelli, lisière et zone plus ou moins rudéralisée, près d’un abri, 28.6.201 2, Delage, A. & C. PanaÏotis cbnc observations et photos; Côte orientale, à la Cala d’Oro, en amont du vieux pont [41°50’N 9°24’E], bords du ruisseau, 11.6.199 2, Deschâtres, R. s.n. (G).
Cette espèce est indiquée par JEANMONOD & GAMISANS (Fl. Corsica (ed. 2): 755, 2013) comme «D?, non revue en Corse depuis 1935». La seconde récolte mentionnée ci-dessus, que nous avons trouvée indéterminée dans l’ex herbier Deschâtres, montrait que la plante pouvait encore être présente dans l’île ce que l’observation de la première mention démontre. Une prospection attentive dans la Plaine-Orientale pourrait encore réserver des surprises sur ces espèces messicoles qu’on pense aujourd’hui disparues. La station de Guagno, quant à elle, est probablement d’implantation récente, la présence de taxons tels que Ranunculus arvensis ou Alopecurus myosuroides nous laissant penser qu’il s’agit des «restes» d’une culture à gibier.
description: Published as part of Jeanmonod, Daniel, 2015, Notes à la flore de Corse, XXV, pp. 109-140 in Candollea 70 (1) on page 126, DOI: 10.15553/c2015v701a10, http://zenodo.org/record/5720895
Special Report 37: Floods of August and September 1971 in New Jersey
Creators: name: No Name Supplied
Publisher: name: State of New Jersey: Department of Environmental Protection, Division of Water Resources
Year: 1972

description: Special Report 37 of the State of New Jersey, Department of Environmental Protection, Division of Water Resources provides hydrologic data needed for planning and design to control or lessen damages from future floods. It includes discussions of the antecedent hydrology and meteorology of the storms; a description of the floods, comparison to previous floods, effects on ground-water levels, sedimentation, and flood frequency; a summary of flood stages and discharges; and detailed information on stage and discharge for August and September 1971.
Special Report 36: Geology and Water Resources of the Wharton Tract and the Mullica River Basin in Southern New Jersey
Creators: name: No Name Supplied
Publisher: name: State of New Jersey: Department of Environmental Protection, Division of Water Resources
Year: 1973

description: Special Report 36 of the State of New Jersey, Department of Environmental Protection, Division of Water Resources evaluates the ground-water resources in the Wharton Tract and the Mullica River Basin in Southern New Jersey. It includes descriptions of the geologic formations, a summary of the general geology and geologic history of the area, discussions of the water-bearing characteristics of the formations, and the quality of the ground water.
Phyllocnistis dorcas Meyrick 1915, n. sp.
Creators: name: Prins, Jurate De
name: Brito, Rosângela
name: Moreira, Gilson Rudinei Pires
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Gracillariidae
Phyllocnistis
Phyllocnistis dorcas

description: Phyllocnistis dorcas Meyrick, 1915
" Phyllocnistis dorcas, n. sp. "—Meyrick, E. 1915b. Transactions of the Entomological Society of London
(2): 241.
Type locality: British Guiana [Guyana], Mallali. Type specimens: Holotype ♀, BMNH.
Distribution: Guyana (Meyrick 1915b: 241). Larval hostplant(s): Unknown.
description: Published as part of Prins, Jurate De, Brito, Rosângela & Moreira, Gilson Rudinei Pires, 2016, An annotated taxonomic checklist of the Neotropical Gracillariidae (Lepidoptera) with links to the information on host plants and parasitoids, pp. 1-51 in Zootaxa 4158 (1) on page 36, DOI: 10.11646/zootaxa.4158.1.1, http://zenodo.org/record/255480
Special Report 35: Water Resources of the Upper Millstone River Basin, New Jersey
Creators: name: No Name Supplied
Publisher: name: State of New Jersey: Department of Environmental Protection, Division of Water Resources
Year: 1972

description: Special Report 35 of the State of New Jersey, Department of Environmental Protection, Division of Water Resources is an evaluation of the water resources of the Upper Millstone River Basin and potential means for their development, with particular reference to the scheme proposed by J. Homer Sanford in 1959. Water management for the basin is considered in some detail, including the possible use of recharge pits and other means of artificial recharge.
title: Transliteration of Place Names, Cartographic Tracing, Interdisciplinary Cooperation. Michele Ruggieri’s Methodology for his Atlas of China (late 16th-early 17th century)
Creators: name: Piastra, Stefano
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2023

description: After summarising data and events relating to the figure of the Jesuit Michele Ruggieri (1543-1607), a pioneer of the period of encounter between East and West in the Modern Age, and his project, which remained at the manuscript stage, to publish the first Western atlas of China, the article analyses in detail, on the basis of the materials that now exist at the State Archives in Rome, the missionary’s working methodology, based on Chinese cartographic sources, their enlargement and transliteration of the toponyms contained therein, and cartographic tracing. Following these operations, a further phase would have seen a professional cartographer succeed Ruggieri in the processing of the maps, which, thus finished, would finally be passed on to the engraver for the copperplate engraving (the latter phase was never completed due to Ruggieri’s death). Further topics addressed are an estimate of Ruggieri’s materials connected to the atlas that were originally intended to be present among the working materials, but which are now destroyed or missing, some epistemological reflections on the nature of the cartography of the atlas, and, finally, some notes on what graphic layout and impact Ruggieri’s atlas would have had if published.
Special Report 34: Ground-Water Resources Cumberland County, New Jersey
Creators: name: No Name Supplied
Publisher: name: State of New Jersey: Department of Environmental Protection, Division of Water Resources
Year: 1971

description: Special Report 34 of the State of New Jersey, Department of Environmental Protection, Division of Water Resources evaluates the general water-bearing characteristics of the aquifers of Cumberland County and points out that while adequate water resources are available to meet the foreseeable future needs, they must be protected by long range planning and careful local control of development.
Phyllocnistis drimiphaga Kawahara, Nishida & Davis 2009, sp. n.
Creators: name: Prins, Jurate De
name: Brito, Rosângela
name: Moreira, Gilson Rudinei Pires
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Gracillariidae
Phyllocnistis
Phyllocnistis drimiphaga

description: Phyllocnistis drimiphaga Kawahara, Nishida & Davis, 2009
" Phyllocnistis drimiphaga Kawahara, Nishida & Davis, sp. n. "—Kawahara, A.Y., Nishida, K. & Davis,
D.R. 2009. ZooKeys 27: 12–17, figs. 2A, 4A–E, 7A–L, 10A–K.
Type locality: Costa Rica, Prov. Heredia, 6 km NE Vara Blanca, 2050 m, 10°10'34"N 084°06'41"W,
emerged 27.i.2004 from Drimys granadensis, leg. K. Nishida.
Type specimens: Holotype ♀, USNM; Paratypes 2 larvae, 3 pupae, 2♂ and 3♀, USNM, UCR, INBIO. Distribution: Costa Rica (Kawahara et al. 2009: 14).
Larval hostplant(s): Winteraceae: Drimys granadensis L. f. (Kawahara et al. 2009: 16). Parasitoids: Encyrtidae: Ageniaspis sp. (Kawahara et al. 2009: 16).
description: Published as part of Prins, Jurate De, Brito, Rosângela & Moreira, Gilson Rudinei Pires, 2016, An annotated taxonomic checklist of the Neotropical Gracillariidae (Lepidoptera) with links to the information on host plants and parasitoids, pp. 1-51 in Zootaxa 4158 (1) on page 36, DOI: 10.11646/zootaxa.4158.1.1, http://zenodo.org/record/255480
title: Vertikale Entsiegelung
Creators: name: Hoppe, Thomas
Publisher: name: TU Wien
Year: 2024
Subjects: subject: Feuermauer
subject: Retentionsspeicher
subject: Klima-Resilienz
subject: Fassadenbegrünung
subject: Wärmepumpe

description: Arbeit an der Bibliothek noch nicht eingelangt - Daten nicht geprueft - gesperrte Arbeit (bis 2026-09-30+02:00)
description: Abweichender Titel nach Übersetzung der Verfasserin/des Verfassers
Characterization of metabolic networks in tumor-initiating cells and their exploitation for prevention of tumor growth
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Tumor-initiating cells; Metabolism; Stemness; Glycolysis; AMP kinase; Breast cancer; Prostate cancer; Oxidative stress; TWIST1; Protein kinase B (AKT); Metformin
Special Report 33: Geology and Ground-Water Resources of Salem County, New Jersey
Creators: name: No Name Supplied
Publisher: name: State of New Jersey: Department of Conservation and Economic Development, Division of Water Policy and Supply
Year: 1969

description: Special Report 33 of the State of New Jersey Department of Conservation and Economic Development, Division of Water Policy and Supply summarizes the geology pertinent to the development of the water resources of Salem County. It evaluates the relative importance of the major aquifers as to their present use and suitability for future development. The quality of the ground-water in each aquifer and the salt-water intrusion problem are discussed.
Targeting FZD7 in human cancers
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: WNT; Frizzled; FZD7; Cancer stem cell; Antibody therapy; Ovarian cancer; Breast cancer
Special Report 31: Surface Water Supply of New Jersey: Streamflow Records, October 1960 to September 1965
Creators: name: No Name Supplied
Publisher: name: State of New Jersey: Department of Conservation and Economic Development, Division of Water Policy and Supply
Year: 1968

description: Special Report 31 of the State of New Jersey Department of Conservation and Economic Development, Division of Water Policy and Supply assembles the records of NJ streams for a five-year period and makes a convenient reference for those who are in need of accurate information on the flow of streams in connection with problems on water works, dams, reservoirs, bridges, flood control works, drainage works and other projects. This report contains the discharge records for 86 stations, records of gage height for 14 stations, month-end contents for 21 reservoirs and lakes, and monthly records of diversion for 12 stations.
Artificial Intelligence Guided Rapid Repurposing of Therapeutics for COVID-19
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: As the rapidly unfolding COVID-19 pandemic claimed its victims around the world, it inspired the Institute for Network Medicine's (iNetMed's) scientists to come up with solutions that are not just going to be impactful in the present but build a roadmap for the future. Phase 1 funding has already helped them overcome two obstacles. First, iNetMed’s scientists within the Center for Precision Computational Systems Network (PreCSN) have used artificial intelligence (AI) to develop the first computational map to navigate the uncharted territory of viral pandemics. This map, built using machine learning to sift through gene expression patterns from over 50,000 datasets, pinpointed the nature and extent of the immune storm that causes fatality in COVID-19 and other pandemics. It also provides an unbiased approach that is backed by mathematical precision to define therapeutic goals and rapidly screen numerous compounds their ability to meet those goals. Second, to put these insights into actionable next steps, iNetMed’s scientists within UC San Diego’s HUMANOID Center of Research Excellence (CoRE) have created lungs-in-a-dish models for screening therapeutics against viral pandemics.

 These accomplishments, all within a short period of time and with limited resources, are now ready to use to test the efficacy of drugs in HTP screens and assess their ability to control viral infection (entry, replication, spread) and the runaway immune response in humans that is seemingly fatal.

 If awarded, the funds during the continuation phase will go largely towards supporting costs for lung organoid monolayers for drug screening and AI guided measurement of which drugs are 'hits' and which are 'misses'. Successful drug candidates can be rapidly translated to the bedside because findings in human organoids are more likely to be relevant to human disease and human tissues. This proposal is for evaluating just that.

 Impact: Growing human complete lung models in cultures is an unvanquished challenge, one that is also very expensive. To validate these models for use in Phase 0, human trials within 1 year is ambitious. This award will be leveraged by multiple ongoing COVID-19 drug screening programs here at UCSD and at other UCs.
Phyllocnistis maxberryi Kawahara, Nishida & Davis 2009, sp. n.
Creators: name: Prins, Jurate De
name: Brito, Rosângela
name: Moreira, Gilson Rudinei Pires
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Gracillariidae
Phyllocnistis
Phyllocnistis maxberryi

description: Phyllocnistis maxberryi Kawahara, Nishida & Davis, 2009
" Phyllocnistis maxberryi Kawahara, Nishida & Davis, sp. n. "—Kawahara, A.Y., Nishida, K. & Davis, D.R.
2009. ZooKeys 27: 17–20, figs. 2B, 5A–F, 8A–L, 11A–I.
Type locality: Costa Rica, Prov. San José, Cerro de la Muerte, Villa Mills, 3100 m, emerged 13.iii.2003
from Gaiadendron punctatum, leg. K. Nishida.
Type specimens: Holotype ♀, USNM; Paratypes 9 larvae, 8 pupae, 7♂ and 2♀, genitalia slides USNM
33279, 33280, 33286, USNM, UCR.
Distribution: Costa Rica (Kawahara et al. 2009: 19).
Larval hostplant(s): Loranthaceae: Gaiadendron punctatum (Ruiz & Pav.) G.Don. (Kawahara et al. 2009:
19).
Parasitoids: Eulophidae: Chrysocharis sp. (Kawahara et al. 2009: 19).
description: Published as part of Prins, Jurate De, Brito, Rosângela & Moreira, Gilson Rudinei Pires, 2016, An annotated taxonomic checklist of the Neotropical Gracillariidae (Lepidoptera) with links to the information on host plants and parasitoids, pp. 1-51 in Zootaxa 4158 (1) on page 36, DOI: 10.11646/zootaxa.4158.1.1, http://zenodo.org/record/255480
The study and treatment of COVID19-related neurological consequences
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: COVID-19 was rapidly declared a pandemic by the World Health Organization and spread to 216 countries in 5 months, with almost thirteen million cases and more than half a million confirmed deaths worldwide. There are now more than three million confirmed cases in the US, with deaths 137,000 as of July 13, 2020. With no vaccines, approved treatments, and a high infectivity rate, COVID-19 quickly became a public health emergency worldwide, leading to lockdowns in many areas of the world, severely affecting daily life. Early clinical care mainly focused on respiratory illnesses. However, a variety of neurological manifestations in both adults and newborns are also emerging. We will characterize the molecular and cellular alterations caused by the SARS-Cov-2 virus in a human model to understand how it affects the brain. At the same time, we will be testing an FDA-approved drug candidate that blocks viral replication in human brain cells (our preliminary data with seed support) to further validate its efficacy in two in vitro models. Altogether, our data show that our drug candidate can successfully inhibit SARS-Cov-2 viral replication and potentially treat infected individuals. A successful outcome in this proposal will lead to a clinical trial with an already FDA-approved repurposed drug. Moreover, our scalable human model, with robust cellular phenotypes, provides a platform for future large-scale drug screens to prevent viral infection or attenuate subsequent pathological effects during neurodevelopment in infected humans.
Special Report 30: Water Resources and Geology of Gloucester County, New Jersey
Creators: name: No Name Supplied
Publisher: name: State of New Jersey: Department of Conservation and Economic Development, Division of Water Policy and Supply
Year: 1969

description: Special Report 30 of the State of New Jersey Department of Conservation and Economic Development, Division of Water Policy and Supply summarizes the geology and water resources of Gloucester County. It evaluates the relative importance of the major aquifers and discusses their sustainability for future development. Areas where water quality may limit an aquifer's use are also defined.
Silvopastoral agroforestry systems for dryland corners in Canterbury farms
Creators: name: Velarde-Pajares, Sandra
name: Wills, Kyle
name: Hajdu, Istvan
name: Tipene, Trent
name: Kalaugher, Electra
Publisher: name: AgResearch
Year: 2024
Subjects: classificationCode: 3002
subject: Agriculture, land and farm management

description: Potential future water constraints on dry areas of Canterbury farms, combined with existing animal welfare requirements, have spurred interest in practices such as agroforestry that can help future proof farming. Agroforestry is the deliberate integration of trees within a livestock grazing system. We surveyed farmers to investigate their understanding of agroforestry, including enablers and barriers to change; and conducted a literature review to identify key agroforestry concepts. We partnered with Ngāi Tahu Farming and Claxby Farms in Canterbury Region to co-develop agroforestry planting plans and completed economic analysis of the agroforestry component of each farm. We also identified other unquantifiable potential benefits of integrating trees on farms. We found that the agroforestry systems designed have positive net present value, internal rate of return, and a positive post carbon income annual cashflow. We have demonstrated that agroforestry is potentially economically viable in Canterbury. Agroforestry systems can be designed to align with the New Zealand Emissions Trading Scheme (NZ ETS) and in turn this would provide financial incentives for establishing trees on dryland corners. The quantified economic outcomes and the identified unquantified benefits warrant further research into integrating agroforestry into dairy and other farming systems around New Zealand.
Special Report No. 29: Geology and Ground-Water Resources of Ocean County, New Jersey
Creators: name: No Name Supplied
Publisher: name: State of New Jersey: Department of Conservation and Economic Development, Division of Water Policy and Supply
Year: 1969

description: Special Report 29 of the State of New Jersey Department of Conservation and Economic Development, Division of Water Policy and Supply evaluates the geologic and hydrologic factors affecting the occurrence, movement, availability, and chemical quality of ground water in Ocean County. It indicates that large amounts of ground water are available for public and industrial supplies in Ocean County. Surface water supplies, largely derived from ground water discharge, also are plentiful.
Serum amylase and novel multi-omics integration to detect and characterize coagulopathy in COVID-19
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: A key insight emerging from the COVID pandemic is the recognition that blood coagulation is severely altered and may be a primary driver of morbidity and mortality. Critically ill COVID+ patients almost universally display an aberrant coagulation profile, indicating a severe disruption of the normal balance between the blood’s ability to clot and bleed. The cause of this imbalance is not well understood; however, we believe that the blood coagulation system is compromised by enzymes originating from the bowel. In order to design an effective clinical intervention against these enzymes we must first understand the temporal mechanisms of COVID-induced coagulopathy. Virtually every organ system is affected by the COVID virus, and the gut is no exception. When the gut does not receive sufficient oxygen from the lungs, it becomes “leaky”, and allows inflammatory digestive enzymes normally contained in the bowel to enter the bloodstream. Digestive enzymes, if able to access the circulation may break down proteins, including those responsible for maintaining the blood coagulation system. Most gut-derived enzymes are rapidly bound by inhibitors in the blood and are thus difficult to detect. As a result, other gut enzymes such as α-amylase are routinely measured. Amylase is a digestive enzyme that breaks down starches; because it has no inhibitors in the blood it is useful for measuring the extent of digestive enzyme penetration into the circulation. In our preliminary results, elevated amylase levels are significantly associated with mortality in COVID+ patients (44% vs 24%), suggesting a potential role for gut-derived enzymes in the blood. To optimally design and implement a clinical trial inhibiting these enzymes we will first determine the temporal profile of COVID coagulopathy using amylase as a marker for circulating digestive enzymes, incorporating state-of-the-art proteomics, peptidomics, and enzyme activity assays of patient blood, integrated with clinical laboratory values. Results from this study will give a detailed understanding of the coagulopathy and role of bowel-derived enzymes in COVID infection, enabling effective clinical interventions. Our sample population will focus on patients suffering disproportionately from COVID: a majority are Hispanic and have key identified risk factors for COVID infection including obesity, hypertension, and diabetes.
Special Report 28: Ground-water Resources of Essex County, New Jersey
Creators: name: No Name Supplied
Publisher: name: State of New Jersey: Department of Conservation and Economic Development, Division of Water Policy and Supply
Year: 1968

description: Special Report 28 of the State of New Jersey Department of Conservation and Economic Development, Division of Water Policy and Supply evaluates the relative importance of the aquifers of Essex County as to their present use and suitability for future development. It indicates which areas are being overpumped and those areas where further ground water exploration would be profitable.
The UCSC SARS-CoV-2 Genome Browser
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The UCSC SARS-CoV-2 Genome Browser is a map viewer for the current epidemic's viral genome sequence. The main users of our website are biomedical researchers. They use the website to look up where genes and proteins are located in the genome, they look at DNA probes that are part of commercial diagnostics kits, conservation of a base pair with other viruses and increasingly at mutations of the genome in human viral isolates. Similar to Google Maps, a graphical website like ours helps a lot with locating information. Our website has become a standard tool for researchers working on the almost 1000 times bigger human genomes and increasingly for this viral genome. Without a map viewer, the everyday work with a 40,000bp long genome is more time-consuming. We constantly update our annotation database with new information as it gets published in the scientific literature. Increasingly, positive human nasopharyngeal samples are also sent for sequencing, and by looking at the mutations, one can sometimes get an idea where someone was infected or whether a group of people were infected by the same person or several ones, to study the spread of the disease or ideally even help with contact tracing. To make this easier, we are showing how existing isolates are related, as a tree next to our map. In addition to further updating our data and improving our software to make the display faster for the tens of thousands of samples that will be sequenced across the US, we would like to allow researchers to upload any new genome sequence. We could then place the uploaded sample on our big tree of all other samples. We hope that all the data updates and new features outlined in this proposal will make it easier to study the virus, visualize the tree structure of sequenced virus samples and that this may help with contact tracing later in the pandemic.
Cerastium tomentosum L.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Caryophyllales
Caryophyllaceae
Cerastium
Cerastium tomentosum

description: Cerastium tomentosum L.
− Vivario, à la sortie du village (direction Corte) [42°10’N 9°10’E], vieux mur (naturalisé), 28.5.198 6, Deschâtres, R. s.n. (G); entre Casanova et Poggio-diVenaco, haut talus argilo-rocheux, 650 m, 16.5.201 3, Alphand, J. s.n. (Hb. privé).
Plante ornementale et subspontanée très rare en Corse et signalée uniquement du secteur d’Incudine-Bavella à Zicavo et Cozzano et du secteur du Rotondu en deux stations de Petreto-Bicchisano (ARGAGNON & HUGOT, Candollea 59: 77-78, 2004; JEANMONOD & SCHLÜSSEL, Candollea 61: 114, 2006; DELAGE, Candollea 65: 282, 2010). La plante est donc nouvelle pour le secteur du Rotondu, elle passe du statut RR (très rare) à celui de R (rare) et doit être considérée comme naturalisée dans l’île.
description: Published as part of Jeanmonod, Daniel, 2015, Notes à la flore de Corse, XXV, pp. 109-140 in Candollea 70 (1) on page 127, DOI: 10.15553/c2015v701a10, http://zenodo.org/record/5720895
Phyllocnistis rotans Meyrick 1915, n. sp.
Creators: name: Prins, Jurate De
name: Brito, Rosângela
name: Moreira, Gilson Rudinei Pires
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Gracillariidae
Phyllocnistis
Phyllocnistis rotans

description: Phyllocnistis rotans Meyrick, 1915
" Phyllocnistis rotans, n. sp. "—Meyrick, E. 1915b. Transactions of the Entomological Society of London (2):
242.
Type locality: Ecuador, Alausi, 9450 ft.
Type specimens: 5 syntypes (♂ and ♀), BMNH. Distribution: Ecuador (Meyrick 1915b: 242). Larval hostplant(s): Unknown.
description: Published as part of Prins, Jurate De, Brito, Rosângela & Moreira, Gilson Rudinei Pires, 2016, An annotated taxonomic checklist of the Neotropical Gracillariidae (Lepidoptera) with links to the information on host plants and parasitoids, pp. 1-51 in Zootaxa 4158 (1) on page 37, DOI: 10.11646/zootaxa.4158.1.1, http://zenodo.org/record/255480
A Graphene-based Multiplexed Sensor for Ultra-fast and Low-cost COVID-19 Diagnosis and Monitoring
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The COVID-19 pandemic is an ongoing global tragedy. Social distancing, self-isolation, and face coverings have been adopted to prevent asymptomatic carriers from infecting vulnerable members of the community. Although widespread COVID-19 infection data would be most effective in evaluating the community spread, there are several bottlenecks to diagnosis and detect disease leading to a backlog of testing and variable results. Standard viral nucleic acid tests are time-consuming and resource-intensive and only identify current carriers. Standard antibody tests are often point-of-care (POC) compatible but do not identify infectious individuals since it is not possible to differentiate between asymptomatic carriers and immune persons. There is thus a need for POC quantitative testing for antibodies and viral products in parallel. We have designed and characterized a novel multiplexed, portable, wireless electrochemical platform for ultra-rapid detection of COVID-19. We plan to measure COVID-19 biomarker concentrations in blood, saliva, and nasopharyngeal swab samples from healthy and infected subjects including viral antigen nucleocapsid protein (NP), COVID-19-specific IgM and IgG antibodies, as well as inflammatory biomarker C-reactive protein (CRP), using immunoassays based on our large-scale mass-producible and low cost laser-engraved graphene (LEG) sensor platform. We demonstrated linear detection in physiologically relevant ranges for blood and saliva with a 1-minute sample incubation. Our multiplexed biosensor provides information in these three aspects: early viral infection (NP), infection stage (IgG and IgM), and disease severity (CRP). We present here the next phase of our project in collaboration with The Lundquist Institute / Harbor-UCLA Medical Center as we move towards Pont of Care (POC) testing with clinical samples. Such a simple POC test that could be conducted at home would help reduce the increasing strain on the healthcare system. Identifying COVID-19 carriers, infected, and immune populations may help to better inform pandemic containment and mitigation strategies. This project may pave the way for a more accessible and more informative diagnostic tool for COVID-19 capable of automatically capturing test results electronically.
Longitudinal Surveillance of Health Care Workers to Correlate SARS-CoV-2 Antibodies with Immunity
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The world’s response to the COVID-19 pandemic depends on answering the following questions: Who has
 already been infected? What is the relationship between prior infection and immunity? How long does immunity
 last? Why do some patients develop severe disease? Measurement of antibodies to the SARS-CoV-2 virus can
 help answer these questions. However, currently available antibody tests suffer from poor specificity due to
 cross-reactivity with other human coronaviruses. In addition, while antibodies could potentially neutralize virus
 and confer immunity, antibodies could also generate a pathologic inflammatory response that worsens severity
 of subsequent infection. Prior studies measuring SARS-CoV-2 antibodies have relied on tests that can only
 measure antibody response to a single target and have not followed participants long-term to determine the
 relationship between antibodies and immunity.
 A coronavirus antigen microarray was recently developed to measure antibodies against a panel of targets from
 the SARS-CoV-2 virus. A model has been trained on positive and negative controls to determine the optimal
 combination of antibody responses that predicts prior SARS-CoV-2 infection with high specificity. A cohort of
 1185 health care workers has been recruited, surveyed for occupational and clinical risk factors, and tested for
 antibodies using this methodology. Preliminary results indicate that 4.5% of health care workers have SARSCoV-
 2 antibodies predictive of prior infection, and that occupational and clinical factors do not significantly impact
 this risk.
 We now propose to extend this study with follow-up visits at 4 months and 10 months to measure the dynamics
 of SARS-CoV-2 antibodies in this health care worker cohort over time. At each study visit, health care workers
 will be surveyed for occupational and clinical risk factors and tested for SARS-CoV-2 antibodies, using both the
 coronavirus antigen microarray for binding antibodies and live virus neutralization assay for neutralizing
 antibodies. These health care workers undergo daily symptom and temperature screening with reflex PCR
 testing for COVID-19, so incidence of infection can be accurately measured in this cohort. We will correlate
 SARS-CoV-2 antibody responses over time with occupational and clinical risk factors and with clinical immunity
 and severity of subsequent disease.
Phyllocnistis sciophanta Meyrick 1915, n. sp.
Creators: name: Prins, Jurate De
name: Brito, Rosângela
name: Moreira, Gilson Rudinei Pires
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Gracillariidae
Phyllocnistis
Phyllocnistis sciophanta

description: Phyllocnistis sciophanta Meyrick, 1915
" Phyllocnistis sciophanta, n. sp. "—Meyrick, E. 1915b. Transactions of the Entomological Society of
London (2): 241–242.
Type locality: Peru, Lima, 500 ft.
Type specimens: Holotype ♂, BMNH.
Distribution: Peru (Meyrick 1915b: 242).
Larval hostplant(s): Unknown.
description: Published as part of Prins, Jurate De, Brito, Rosângela & Moreira, Gilson Rudinei Pires, 2016, An annotated taxonomic checklist of the Neotropical Gracillariidae (Lepidoptera) with links to the information on host plants and parasitoids, pp. 1-51 in Zootaxa 4158 (1) on page 37, DOI: 10.11646/zootaxa.4158.1.1, http://zenodo.org/record/255480
Innate immune responses against COVID-19 in the elderly and those with underlying conditions
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: COVID-19 pandemic has affected millions worldwide. Though mild in most cases, a subset of individuals suffer from severe disease that requires hospitalizations and can be fatal. Studies indicate that older individuals and those suffering from underlying diseases such as diabetes, hypertension, heart disease etc. are at higher risk for severe illness from the COVID-19. These individuals are unable mount an effective immune response against the virus to clear it from their body. This leads to increased viral multiplication and pneumonia like symptoms in the lung. Innate immune system cells including dendritic cells and macrophages/monocytes are amongst the first cells to respond to the coronavirus. They produce various protective cytokines that can prevent virus from replicating. In addition, these cells also prime the downstream adaptive immune response including induction of killer T cells that are required to kill the virus. The innate immune response occurs very early within 1-2 days of infection. Emerging data from studies indicates that the killer T cell response is decreased in subjects with severe disease. Data regarding functions of dendritic cells and monocytes in the high risk population is limited. It is difficult to study the response of these cell populations in the COVID-19 infected patients as by the time they are diagnosed with the disease; innate immune response is primarily over. Our hypothesis is that the functions of dendritic cells and monocytes are changed in the high risk individuals rendering them more susceptible to COVID-19. We plan to determine the changes in the functions of these cells in the high risk subjects (elderly and those with underlying conditions) by comparing them to healthy subjects. We hope that the information will help develop therapeutic and preventative measures to protect the vulnerable population.
Sewage Surveillance to monitor COVID19 outbreak
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Clues to the spread of the COVID-19 pandemic are flowing from a surprising place. UCI biological scientists led by Molecular Biology and Biochemistry Associate Professor Katrine Whiteson, Dr. Jason Rothman and Dr. Theresa Loveless are working to identify the virus SARS-CoV-2 through wastewater. Monitoring sewage provides a glimpse of SARS-CoV-2’s diversity and extent without relying on clinical detection or further burdening hospitals or clinics.

 Detecting viral diseases this way has precedent: In 2013, a poliovirus outbreak in Israel was first found by examining sewage. More recently, a Dutch team published research in March, 2020 showing SARS-CoV-2 could be detected in wastewater before infected patients were diagnosed. Interest in wastewater based epidemiology has since expanded as a tool for tracking SARS-CoV-2 in communities.

 The Whiteson lab worked with sewage samples for several years, with the goal of identifying alternatives to antibiotics by isolating viruses that are active against disease-causing bacteria. As soon as the COVID-19 outbreak began, the group realized they could test sewage to see if SARS-CoV-2 was present, and if so, to what extent. The approach would uncover this crucial information before clinical testing was conducted.

 As UCI labs shut-down, Dr. Whiteson and her team shifted to working remotely, and started designing protocols to detect SARS-CoV-2 in wastewater. They brainstormed with others at UCI and nationwide on methods to concentrate the virus, which despite its often-devastating impact, appears to be delicate in wastewater. The biggest impediment to the project was obtaining sewage samples during a time when sanitation districts were modifying their operations to concentrate on essential public safety obligations. However, partnerships with the Southern California Coastal Water Research Project and the City of Escondido have given the team an opportunity to try their methods. So far, the team has detected the SARS-CoV-2 virus at all eight Southern California wastewater facilities assayed. During the next year, they propose to survey SARS-CoV-2 genomes from 12-18 samples/week from the same eight wastewater treatment plants. The wastewater surveillance methods being established will be useful for continued monitoring of SARS-CoV-2 evolution, and could be applied to future outbreaks of other human pathogens.
A Community Driven Response to Inequities of the COVID-19 Pandemic and Recession
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The COVID-19 pandemic highlights health inequities experienced by communities of color or low-income—health inequities ultimately generated by persistent structural racism and inequities in the social determinants of health (i.e., economic stability, neighborhood environment, health care, social circumstances, and education). Communities of color in California, including Black, Latinx, and Indigenous communities, have higher COVID-19 infection and death rates. Shelter-in-place guidelines and the pandemic-related economic recession have greater consequences for these communities. Thus, the pandemic and recession will exacerbate health inequities for communities of color or low-income for years to come. We propose a Racial Equity Rapid Response Team to address disparities in COVID-19 risk and worsening social determinants that have resulted from the pandemic and recession. We have three aims. First, we aim to describe on-the-ground conditions among individuals and communities of color or low-income. We will use an innovative mobile health application (“app”) to collect real-time data from individuals about their communities in the form of neighborhood reports around what is working or not working for them. Individuals will also respond to surveys about their own circumstances (e.g., employment, food, housing, and well-being). We will analyze neighborhood reports and survey data to describe current conditions among individuals and communities, and changes in conditions over the study period. Our second aim is to develop program and policy to guide local, regional, and state support to individuals and communities. Results from Aim 1 will be combined with data on existing resources (e.g., support services) and population-level data on neighborhoods (e.g., socioeconomic status and demographics) across the state in order to inform programs and policies that support effective resource provision. This evidence-based approach is intended to assure that effective and timely support reaches the people and communities who need it most. Third, we aim to establish a set of measures and data visualization tools for continued monitoring of social determinants of health over time. Thus, our proposed project will empower community-based organizations, foundations, and governments at all levels to provide high priority resources in an equitable and accessible manner.
Phyllocnistis sexangula Meyrick 1915, n. sp.
Creators: name: Prins, Jurate De
name: Brito, Rosângela
name: Moreira, Gilson Rudinei Pires
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Gracillariidae
Phyllocnistis
Phyllocnistis sexangula

description: Phyllocnistis sexangula Meyrick, 1915
" Phyllocnistis sexangula, n. sp. "—Meyrick, E. 1915b. Transactions of the Entomological Society of London
(2): 242.
Type locality: Peru, Matucana, 7780 ft.
Type specimens: Syntypes 2♀, BMNH.
Distribution: Peru (Meyrick 1915b: 242).
Larval hostplant(s): Unknown.
description: Published as part of Prins, Jurate De, Brito, Rosângela & Moreira, Gilson Rudinei Pires, 2016, An annotated taxonomic checklist of the Neotropical Gracillariidae (Lepidoptera) with links to the information on host plants and parasitoids, pp. 1-51 in Zootaxa 4158 (1) on page 37, DOI: 10.11646/zootaxa.4158.1.1, http://zenodo.org/record/255480