Additional file 1: of Effect of different methods of cooling for targeted temperature management on outcome after cardiac arrest: a systematic review and meta-analysis
Creators: name: CalabrĂł, Lorenzo
name: Wulfran Bougouin
name: Cariou, Alain
name: Fazio, Chiara De
name: Skrifvars, Markus
name: Soreide, Eldar
name: Creteur, Jacques
name: Kirkegaard, Hans
name: StĂŠphane Legriel
name: Jean-Baptiste Lascarrou
name: Megarbane, Bruno
name: Deye, Nicolas
name: Taccone, Fabio
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: FOS: Health sciences
subject: Computational Biology

description: Table S1. Extracted data in each study assessed for eligibility. Table S2. Full text articles excluded, not fitting eligibility criteria. Figure S1. and S2. Funnel plot for studies comparing the impact of core and surface methods on poor neurological outcome (left) and mortality (right). The outer dashed lines indicate the triangular region within which 95% of studies are expected to lie in the absence of biases and heterogeneity. The solid vertical line corresponds to no intervention effect. Figure S3. Forest plot of mortality in randomized clinical trials (RCTs) or non-RCTs: invasive vs. non-invasive TTM methods. Size of squares for risk ratio reflects weight of trial in pooled analysis. Horizontal bars represent 95% confidence intervals. Figure S4. and S5. Funnel plot for studies comparing the impact of invasive and non-invasive TTM methods on poor neurological outcome (left) and mortality (right). The outer dashed lines indicate the triangular region within which 95% of studies are expected to lie in the absence of biases and heterogeneity. The solid vertical line corresponds to no intervention effect. Figure S6. Forest plot of mortality in randomized clinical trials (RCTs) or non-RCTs: temperature feedback device (TFD) vs. non-TFD TTM methods. Size of squares for risk ratio reflects weight of trial in pooled analysis. Horizontal bars represent 95% confidence intervals. Figure S7. and S8. Funnel plot for studies comparing the impact of temperature feedback device (TFD) and non-TFD TTM methods on poor neurological outcome (left) and mortality (right). The outer dashed lines indicate the triangular region within which 95% of studies are expected to lie in the absence of biases and heterogeneity. The solid vertical line corresponds to no intervention effect. Figure S9. Forest plot of poor neurological outcome in randomized clinical trials (RCTs) or non-RCTs: endovascular devices vs. air- or water-circulating blankets. Size of squares for risk ratio reflects weight of trial in pooled analysis. Horizontal bars represent 95% confidence intervals. Figure S10. Forest plot of mortality in randomized clinical trials (RCTs) or non-RCTs: endovascular devices vs. air- or water-circulating blankets. Size of squares for risk ratio reflects weight of trial in pooled analysis. Horizontal bars represent 95% confidence intervals. Figure S11. and S12. Funnel plot for studies comparing the impact of endovascular devices vs. air- or water-circulating blankets on poor neurological outcome (left) and mortality (right). The outer dashed lines indicate the triangular region within which 95% of studies are expected to lie in the absence of biases and heterogeneity. The solid vertical line corresponds to no intervention effect. Figure S13. Forest plot of poor neurological outcome in randomized clinical trials (RCTs) or non-RCTs: endovascular devices vs. air- or water-circulating blankets with temperature feedback device (TFD). Size of squares for risk ratio reflects weight of trial in pooled analysis. Horizontal bars represent 95% confidence intervals. Figure S14. Forest plot of mortality in randomized clinical trials (RCTs) or non-RCTs: endovascular devices vs. air- or water-circulating blankets with temperature feedback device (TFD). Size of squares for risk ratio reflects weight of trial in pooled analysis. Horizontal bars represent 95% confidence intervals. Figure S15. and S16. Funnel plot for studies comparing the impact of endovascular devices vs. air- or water-circulating blankets with temperature feedback device (TFD) on poor neurological outcome (left) and mortality (right). The outer dashed lines indicate the triangular region within which 95% of studies are expected to lie in the absence of biases and heterogeneity. The solid vertical line corresponds to no intervention effect. Figure S17. Forest plot of poor neurological outcome in randomized clinical trials (RCTs) or non-RCTs: blankets vs. other surface TTM methods. Size of squares for risk ratio reflects weight of trial in pooled analysis. Horizontal bars represent 95% confidence intervals. Figure S18. Forest plot of mortality in randomized clinical trials (RCTs) or non-RCTs: blankets vs. other surface TTM methods. Size of squares for risk ratio reflects weight of trial in pooled analysis. Horizontal bars represent 95% confidence intervals. Figure S19. and S20. Funnel plot for studies comparing the impact of blankets vs. other surface TTM methods on poor neurological outcome (left) and mortality (right). The outer dashed lines indicate the triangular region within which 95% of studies are expected to lie in the absence of biases and heterogeneity. The solid vertical line corresponds to no intervention effect. (DOCX 6046 kb)