cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
THE EFFECTIVENESS OF A PREDIABETES PROTOCOL FOR DIABETES PREVENTION
Creators: name: Arianna Lanier
Publisher: name: Zenodo
Year: 2024
Subjects: T2DM
prediabetes
DPP
Hgb A1c
BMI
weight

description: Type 2 Diabetes (T2DM) is a daunting diagnosis associated with multiple comorbidities. Prediabetes remains a major predisposing factor in the development of T2DM. Therefore, the Centers for Disease Control and Prevention [CDC] (2021a) developed a Diabetes prevention program (DPP) to combat the increasing number of those diagnosed with T2DM. There has been sufficient evidence that supports the effectiveness of DPPs in preventing T2DM along with other benefits, including a decrease in weight, body mass index (BMI), and blood pressure. Yet, these programs remain under-used. This pilot DPP project aimed to improve the clinic's current process and evaluate the effectiveness of weekly classes on diabetes prevention based on the CDC's DPP. Participants included adults over the age of 18. Participant variables in the project included hemoglobin A1c (Hgb A1c), weight, BMI, blood pressure, and a self-reported questionnaire. Five out of seven participants completed the project. There was an overall decrease in weight, BMI, Hgb A1c, and blood pressure. Additionally, there was an increase in the questionnaire scores that reflected an increase in healthy eating habits, highlighting the importance of lifestyle changes in diabetes prevention and a healthy lifestyle overall.
Agrarian pre-emption and company-relations
Creators: name: Mauro, Mario
Publisher: name: Aestimum
Year: 2018

description: Membership contracts are excluded from the agrarian pre-emption regulation. In order to abuse of this exemption, some entrepreneurs build complex corporate negotiations. Moving from two recent sentences of the Italian Supreme Court, the paper investigates the reasons that justify the legislator’s choice, isolates some instruments for deciphering abusive conducts and selects the most effective remedy to protect the excluded pre-emptioner.
description: Aestimum, Aestimum 71 (2017)
Supplementary materials from Inferring collective behaviour from a fossilized fish shoal
Creators: name: Mizumoto, Nobuaki
name: Miyata, Shinya
name: Pratt, Stephen C.
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences
subject: 60801 Animal Behaviour

description: Supplementary text and figure S1-7 and table S1 are available.
(1259) Florence Everard Upton
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
New results on inconsistency indices and their relationship with the quality of priority vector estimation
Creators: name: Grzybowski, Andrzej Z.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: The article is devoted to the problem of inconsistency in the pairwise comparisons based prioritization methodology. The issue of "inconsistency" in this context has gained much attention in recent years. The literature provides us with a number of different "inconsistency" indices suggested for measuring the inconsistency of the pairwise comparison matrix (PCM). The latter is understood as a deviation of the PCM from the "consistent case" - a notion that is formally well-defined in this theory. However the usage of the indices is justified only by some heuristics. It is still unclear what they really "measure". What is even more important and still not known is the relationship between their values and the "consistency" of the decision maker's judgments on one hand, and the prioritization results upon the other. We provide examples showing that it is necessary to distinguish between these three following tasks: the "measuring" of the "PCM inconsistency" and the PCM-based "measuring" of the consistency of decision maker's judgments and, finally, the "measuring" of the usefulness of the PCM as a source of information for estimation of the priority vector (PV). Next we focus on the third task, which seems to be the most important one in Multi-Criteria Decision Making. With the help of Monte Carlo experiments, we study the performance of various inconsistency indices as indicators of the final PV estimation quality. The presented results allow a deeper understanding of the information contained in these indices and help in choosing a proper one in a given situation. They also enable us to develop a new inconsistency characteristic and, based on it, to propose the PCM acceptance approach that is supported by the classical statistical methodology.
description: 26 pages, 2 figures, 19 tables
Meta-Analyses of the Relation between Silicone Breast Implants and the Risk of Connective-Tissue Diseases
Creators: name: Janowsky, Esther C.
name: Kupper, Lawrence L.
name: Hulka, Barbara S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: BACKGROUND: The postulated relation between silicone breast implants and the risk of connective-tissue and autoimmune diseases has generated intense medical and legal interest during the past decade. The salience of the issue persists, despite the fact that a great deal of research has been conducted on this subject. To provide a stronger quantitative basis for addressing the postulated relation, we applied several techniques of meta-analysis that combine, compare, and summarize the results of existing relevant studies.

METHODS: We searched data bases and reviewed citations in relevant articles to identify studies that met prestated inclusion criteria. Nine cohort studies, nine case-control studies, and two cross-sectional studies were included in our meta-analyses. We conducted meta-analyses of the results of these studies, both with and without adjustment for confounding factors, and a separate analysis restricted to studies of silicone-gel-filled breast implants. Finally, we estimated the annual number of new cases of connective-tissue disease that could be attributed to breast implants.

RESULTS: There was no evidence that breast implants were associated with a significant increase in the summary adjusted relative risk of individual connective-tissue diseases (rheumatoid arthritis, 1.04 [95 percent confidence interval, 0.72 to 1.51]; systemic lupus erythematosus, 0.65 [95 percent confidence interval, 0.35 to 1.23]; scleroderma or systemic sclerosis, 1.01 [95 percent confidence interval, 0.59 to 1.73]; and Sjögren's syndrome, 1.42 [95 percent confidence interval, 0.65 to 3.11]); all definite connective-tissue diseases combined (0.80; 95 percent confidence interval, 0.62 to 1.04); or other autoimmune or rheumatic conditions (0.96; 95 percent confidence interval, 0.74 to 1.25). Nor was there evidence of significantly increased risk in the unadjusted analyses or in the analysis restricted to silicone-gel-filled implants.

CONCLUSIONS: On the basis of our meta-analyses, there was no evidence of an association between breast implants in general, or silicone-gel-filled breast implants specifically, and any of the individual connective-tissue diseases, all definite connective-tissue diseases combined, or other autoimmune or rheumatic conditions. From a public health perspective, breast implants appear to have a minimal effect on the number of women in whom connective-tissue diseases develop, and the elimination of implants would not be likely to reduce the incidence of connective-tissue diseases.
(1254) John Upton
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Il valore del paesaggio a Posillipo tra ambiente naturale e costruito
Creators: name: Guarino, Mario
Publisher: name: Aestimum
Year: 2018

description: In this study the hedonic price method is applied to evaluate the externalities diffused by a landscape of extraordinary beauty consisting in natural resources and historic/artistic villas on the coast of Posillipo in Naples. The construction of hedonimetric curves is proposed as an approach to assess economic value of the landscape at Posillipo. The functions related to these curves derive from a plurality of hedonic prices, linked to the panorama and to the quality of historic/artistic villas that arise on the coastal strip between via Posillipo and the sea.
description: Aestimum, Aestimum 71 (2017)
Spark Discharge Generator as a Stable and Reliable Nanoparticle Synthesis Device: Analysis of the Impact of Process and Circuit Variables on the Characteristics of Synthesized Nanoparticles
Creators: name: Vazquez-Pufleau, Miguel
name: Gomez-Palos, Isabel
name: Arevalo, Luis
name: Garcia-Labanda, Javier
name: Vilatela, Juan Jose
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Nanotechnology offers the promise of harnessing quantum properties not available in the bulk phase. These desirable properties are highly dependent on size and composition. Generators that control these variables are therefore essential for progress in the field. The spark discharge generator (SDG) is an outstanding aerosol route for nanoparticle synthesis, which stands out due to its fast kinetics, scalability, high purity, accuracy and reproducibility with the added advantage of allowing the synthesis of nanoparticles of any conducting material. These advantages are a consequence of its vast heating and cooling rates, its intrinsic and easily controllable electronic variables at the reach of a click. However, the mechanistic impact of these variables on the actual aerosol generated is still not fully understood. In this work, we constructed an SDG and systematically studied its behavior with particular interest in the effect that resistance, capacitance, inductance, flow rate, gap separation and current have on the electrical behavior of the spark. Our model system produced primarily Fe and Cu nanoparticles with measured concentrations. We discuss how the spark influences particle size and number concentration and provide useful correlations that link dependent with independent variables. Remarkably, a finite resistance produces a maximum in the output of the generated aerosols. This suggests a direct link between RLC properties of the circuit and cabling into the frequency of the spark, and nanoparticle number concentration, indicating potential for exploiting such behavior towards maximizing nanoparticle generation. Furthermore, we discuss a link between spark oscillations and energy release with its consequent aerosol generation.
description: SI included at the end
Baryon and chiral symmetry breaking in holographic QCD
Creators: name: Gorsky, Alexander
name: Gudnason, Sven Bjarke
name: Krikun, Alexander
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the relationship between chiral symmetry breaking and baryons in holographic QCD. We construct a soliton with unit baryon charge in the presence of a nonzero mean value of the scalar bifundamental field, which is dual to the chiral condensate. We obtain a relation between the chiral condensate and the mass of the baryon and find in a clear-cut way that at large values of the condensate the holographic soliton is no longer located on the IR wall. Instead it is split into two halves, which are symmetrically located on the left and right flavor branes. On the other hand we find that the local value of the quark condensate is suppressed in the core of the soliton, which is evidence for a partial chiral symmetry restoration inside the baryon.
description: 26 pages, 8 figures
(1255) Catherine Lapage
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Universal quantum simulation with prethreshold superconducting qubits: Single-excitation subspace method
Creators: name: Geller, Michael R.
name: Martinis, John M.
name: Sornborger, Andrew T.
name: Stancil, Phillip C.
name: Pritchett, Emily J.
name: You, Hao
name: Galiautdinov, Andrei
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Current quantum computing architectures lack the size and fidelity required for universal fault-tolerant operation, limiting the practical implementation of key quantum algorithms to all but the smallest problem sizes. In this work we propose an alternative method for general-purpose quantum computation that is ideally suited for such "prethreshold" superconducting hardware. Computations are performed in the n-dimensional single-excitation subspace (SES) of a system of n tunably coupled superconducting qubits. The approach is not scalable, but allows many operations in the unitary group SU(n) to be implemented by a single application of the Hamiltonian, bypassing the need to decompose a desired unitary into elementary gates. This feature makes large, nontrivial quantum computations possible within the available coherence time. We show how to use a programmable SES chip to perform fast amplitude amplification and phase estimation, two versatile quantum subalgorithms. We also show that an SES processor is well suited for Hamiltonian simulation, specifically simulation of the Schrodinger equation with a real but otherwise arbitrary nxn Hamiltonian matrix. We discuss the utility and practicality of such a universal quantum simulator, and propose its application to the study of realistic atomic and molecular collisions.
description: 25 pages
Tables and Figures from Geographical and host species barriers differentially affect generalist and specialist parasite community structure in a tropical sky-island archipelago.
Creators: name: Gupta, Pooja
name: C. K. Vishnudas
name: Ramakrishnan, Uma
name: V. V. Robin
name: Guha Dharmarajan
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences

description: Geographic sampling location information, Parasite prevalence per host species with the number of unique parasite lineages, parasite lineage names and GenBank accession numbers, host ecological trait data, other tables and figures supporting the conclusions of this study.
Neighborhood of Residence and Incidence of Coronary Heart Disease
Creators: name: Diez Roux, Ana V.
name: Merkin, Sharon Stein
name: Arnett, Donna
name: Nieto, F. Javier
name: Tyroler, Herman A.
name: Chambless, Lloyd
name: Sorlie, Paul
name: Szklo, Moyses
name: Massing, Mark
name: Watson, Robert L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: BACKGROUND: Where a person lives is not usually thought of as an independent predictor of his or her health, although physical and social features of places of residence may affect health and health-related behavior. METHODS: Using data from the Atherosclerosis Risk in Communities Study, we examined the relation between characteristics of neighborhoods and the incidence of coronary heart disease. Participants were 45 to 64 years of age at base line and were sampled from four study sites in the United States: Forsyth County, North Carolina; Jackson, Mississippi; the northwestern suburbs of Minneapolis; and Washington County, Maryland. As proxies for neighborhoods, we used block groups containing an average of 1000 people, as defined by the U.S. Census. We constructed a summary score for the socioeconomic environment of each neighborhood that included information about wealth and income, education, and occupation. RESULTS: During a median of 9.1 years of follow-up, 615 coronary events occurred in 13,009 participants. Residents of disadvantaged neighborhoods (those with lower summary scores) had a higher risk of disease than residents of advantaged neighborhoods, even after we controlled for personal income, education, and occupation. Hazard ratios for coronary events in the most disadvantaged group of neighborhoods as compared with the most advantaged group--adjusted for age, study site, and personal socioeconomic indicators--were 1.7 among whites (95 percent confidence interval, 1.3 to 2.3) and 1.4 among blacks (95 percent confidence interval, 0.9 to 2.0). Neighborhood and personal socioeconomic indicators contributed independently to the risk of disease. Hazard ratios for coronary heart disease among low-income persons living in the most disadvantaged neighborhoods, as compared with high-income persons in the most advantaged neighborhoods were 3.1 among whites (95 percent confidence interval, 2.1 to 4.8) and 2.5 among blacks (95 percent confidence interval, 1.4 to 4.5). These associations remained unchanged after adjustment for established risk factors for coronary heart disease. CONCLUSIONS: Even after controlling for personal income, education, and occupation, we found that living in a disadvantaged neighborhood is associated with an increased incidence of coronary heart disease.
An innovative methodological and operational approach to developing Management Plans for UNESCO World Heritage Sites: a Geographic Information System for “Ivrea, industrial city of the 20th century”
Creators: name: Barreca, Alice
name: Curto, Rocco
name: Rolando, Diana
Publisher: name: Aestimum
Year: 2018

description: The model for developing Management Plans for UNESCO World Heritage Sites drawn up by the Italian Ministry of Cultural Heritage and Activities in 2005 is no longer wholly adequate in terms of promoting heritage resources and their local contexts. The article considers the innovation developed in the IT/ICT field and provides theoretical and methodological considerations, based on which a new methodology for devising Management Plans could be developed. A Geographic Information System (GIS) for the knowledge and management of the site “Ivrea, industrial city of the 20th century”, is proposed as an innovative, dynamic, interoperable model that can both support urban-scale projects to capture the economic value of cultural heritage and promote forms of indirect enjoyment of the site.
description: Aestimum, Aestimum 71 (2017)
(1252) William Barry Postlethwaite
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Evoluzione della dimensione delle imprese agricole: un’analisi esplorativa mediante configural frequency analysis
Creators: name: Corsi, Stefano
name: Guastella, Giovanni
name: Pareglio, Stefano
name: Tosini, Andrea
Publisher: name: Aestimum
Year: 2018

description: Investment support measures in agriculture can have differentiated effects on the strategic reorganisation and the performance of farms. In this paper, we study the patterns of technical change of a sample of farms in the Lombardy region, Italy, that invested in structural modernisation benefiting from the financial incentives provided under the measure 121. We find evidence relating the modernisation of farms under the umbrella of the measure 121 to limited positive changes in farmland and more substantial positive changes in other inputs. The results are not conclusive regarding a causal relationship between the measure 121 and the structural change of farms. Nonetheless, the paper describes a situation in which patterns of farmland reduction are relatively less frequent in farms that make use of this policy instrument.
description: Aestimum, Aestimum 71 (2017)
MRS Modular UAV Hardware Platforms for Supporting Research in Real-World Outdoor and Indoor Environments
Creators: name: Hert, Daniel
name: Baca, Tomas
name: Petracek, Pavel
name: Kratky, Vit
name: Spurny, Vojtech
name: Petrlik, Matej
name: Vrba, Matous
name: Zaitlik, David
name: Stoudek, Pavel
name: Walter, Viktor
name: Stepan, Petr
name: Horyna, Jiri
name: Pritzl, Vaclav
name: Silano, Giuseppe
name: Licea, Daniel Bonilla
name: Stibinger, Petr
name: Penicka, Robert
name: Nascimento, Tiago
name: Saska, Martin
Publisher: name: arXiv
Year: 2023
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: This paper presents a family of autonomous Unmanned Aerial Vehicles (UAVs) platforms designed for a diverse range of indoor and outdoor applications. The proposed UAV design is highly modular in terms of used actuators, sensor configurations, and even UAV frames. This allows to achieve, with minimal effort, a proper experimental setup for single, as well as, multi robot scenarios. Presented platforms are intended to facilitate the transition from simulations, and simplified laboratory experiments, into the deployment of aerial robots into uncertain and hard-to-model real-world conditions. We present mechanical designs, electric configurations, and dynamic models of the UAVs, followed by numerous recommendations and technical details required for building such a fully autonomous UAV system for experimental verification of scientific achievements. To show strength and high variability of the proposed system, we present results of tens of completely different real-robot experiments in various environments using distinct actuator and sensory configurations.
description: 10 pages, 17 figures, conference
The EMAS-ISO standards in the quality assessment of the integrated water service
Creators: name: Giuffrida, Salvatore
name: Casamassima, Giovanni
name: Trovato, Maria Rosa
Publisher: name: Aestimum
Year: 2017

description: This contribution proposes a theoretical model to support the environmental assessment for the organizations aiming at implementing an EMAS-ISO auditing process in the ground of the water services industry. The model tries to combine a new theory of value – based on natural, bio-genealogical and semantic surplus – with the cycle input - output - re-input characterizing namely the most critical area of the integrated waters service, the waste water treatment plants. A multidimensional pattern based on the Multi-Attribute Value Theory has been assumed as an effective operational framework connecting the contents of the treatment process, as defined by the scientific and technological tools supporting the judges of fact, and the issues of sustainability, supporting the value judgements.
description: Aestimum, Aestimum 70 (2017)
Laboratory and statistical methods from Geographical and host species barriers differentially affect generalist and specialist parasite community structure in a tropical sky-island archipelago.
Creators: name: Gupta, Pooja
name: C. K. Vishnudas
name: Ramakrishnan, Uma
name: V. V. Robin
name: Guha Dharmarajan
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences

description: Detailed information on field sampling; PCR, DNA sequencing; parasite/host phylogenetic analyses; host specificity and co-phylogenetic analyses.
Gas inside the 97 au cavity around the transition disk Sz\,91
Creators: name: Canovas, H.
name: Schreiber, M. R.
name: Cáceres, C.
name: Ménard, F.
name: Pinte, C.
name: Mathews, G. S.
name: Cieza, L.
name: Casassus, S.
name: Hales, A.
name: Williams, J. P.
name: Román, P.
name: Hardy, A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present ALMA (Cycle 0) band-6 and band-3 observations of the transition disk Sz\,91. The disk inclination and position angle are determined to be $i=49.5\degr\pm3.5\degr$ and $\mathrm{PA}=18.2\degr\pm3.5\degr$ and the dusty and gaseous disk are detected up to $\sim220$ au and $\sim400$ au from the star, respectively. Most importantly, our continuum observations indicate that the cavity size in the mm-sized dust distribution must be $\sim97$ au in radius, the largest cavity observed around a T Tauri star. Our data clearly confirms the presence of \co(2-1) well inside the dust cavity. Based on these observational constrains we developed a disk model that simultaneously accounts for the \co and continuum observations (i.e., gaseous and dusty disk). According to our model, most of the millimeter emission comes from a ring located between 97 and 140 au. We also find that the dust cavity is divided into an innermost region largely depleted of dust particles ranging from the dust sublimation radius up to 85 au, and a second, moderately dust-depleted region, extending from 85 to 97 au. The extremely large size of the dust cavity, the presence of gas and small dust particles within the cavity and the accretion rate of Sz\,91 are consistent with the formation of multiple (giant) planets.
description: Accepted for publication in ApJ
Visual perception is highly flexible and context-dependent in young infants: A case of top-down modulated motion perception
Creators: name: Gabriel (Naiqi) Xiao
name: Emberson, Lauren
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Cognitive Psychology
subject: Developmental Psychology
subject: Psychology
subject: FOS: Psychology
subject: Social and Behavioral Sciences

description: Experiment program, analysis scripts, and raw data
Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection
Creators: name: Shiffman, Mitchell L.
name: Rajender Reddy, K.
name: Lin, Amy
name: Carosi, Giampiero
name: Marinos, George
name: Dhumeaux, Daniel
name: Hoffman, Joseph
name: Yu, Jian
name: Smith, Coleman
name: Gonçales Jr., Fernando L.
name: Häussinger, Dieter
name: Diago, Moises
name: Fried, Michael W.
name: Craxi, Antonio
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Background Treatment with peginterferon alfa-2a alone produces significantly higher sustained virologic responses than treatment with interferon alfa-2a alone in patients with chronic hepatitis C virus (HCV) infection. We compared the efficacy and safety of peginterferon alfa-2a plus ribavirin, interferon alfa-2b plus ribavirin, and peginterferon alfa-2a alone in the initial treatment of chronic hepatitis C. Methods A total of 1121 patients were randomly assigned to treatment and received at least one dose of study medication, consisting of 180 μg of peginterferon alfa-2a once weekly plus daily ribavirin (1000 or 1200 mg, depending on body weight), weekly peginterferon alfa-2a plus daily placebo, or 3 million units of interferon alfa-2b thrice weekly plus daily ribavirin for 48 weeks. Results A significantly higher proportion of patients who received peginterferon alfa-2a plus ribavirin had a sustained virologic response (defined as the absence of detectable HCV RNA 24 weeks after cessation of therapy) than of patients who received interferon alfa-2b plus ribavirin (56 percent vs. 44 percent, P<0.001) or peginterferon alfa-2a alone (56 percent vs. 29 percent, P<0.001). The proportions of patients with HCV genotype 1 who had sustained virologic responses were 46 percent, 36 percent, and 21 percent, respectively, for the three regimens. Among patients with HCV genotype 1 and high base-line levels of HCV RNA, the proportions of those with sustained virologic responses were 41 percent, 33 percent, and 13 percent, respectively. The overall safety profiles of the three treatment regimens were similar; the incidence of influenza-like symptoms and depression was lower in the groups receiving peginterferon alfa-2a than in the group receiving interferon alfa-2b plus ribavirin. Conclusions In patients with chronic hepatitis C, once-weekly peginterferon alfa-2a plus ribavirin was tolerated as well as interferon alfa-2b plus ribavirin and produced significant improvements in the rate of sustained virologic response, as compared with interferon alfa-2b plus ribavirin or peginterferon alfa-2a alone.
Toward sustainable management of drinking water: evidence from a choice experiment among Italian water kiosks users
Creators: name: Marangon, Francesco
name: Troiano, Stefania
Publisher: name: Aestimum
Year: 2017

description: The consumption of water kiosk has been increasing in Italy. Nevertheless, only a few studies have analyzed this phenomenon and users’ behavior and preferences. The aim of this study is to fulfill this gap analysing the preferences of consumers toward water from water kiosks in Friuli Venezia Giulia Region. The data collected were analyzed firstly by means of a multinomial logit model, secondly we applied a latent class model. The findings show consumers’ concerns regarding the presence of potentially harmful chemical substances and put in evidence the opportunities in utilizing an environmental certification.
description: Aestimum, Aestimum 70 (2017)
Tables and Figures from Geographical and host species barriers differentially affect generalist and specialist parasite community structure in a tropical sky-island archipelago
Creators: name: Gupta, Pooja
name: C. K. Vishnudas
name: Ramakrishnan, Uma
name: V. V. Robin
name: Guha Dharmarajan
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences

description: Geographic sampling location information, Parasite prevalence per host species with the number of unique parasite lineages, parasite lineage names and GenBank accession numbers, host ecological trait data, other tables and figures supporting the conclusions of this study.
Renormalising entanglement distillation
Creators: name: Waeldchen, Stephan
name: Gertis, Janina
name: Campbell, Earl T.
name: Eisert, Jens
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Entanglement distillation refers to the task of transforming a collection of weakly entangled pairs into fewer highly entangled ones. It is a core ingredient in quantum repeater protocols, needed to transmit entanglement over arbitrary distances in order to realise quantum key distribution schemes. Usually, it is assumed that the initial entangled pairs are i.i.d. distributed and uncorrelated with each other, an assumption that might not be reasonable at all in any entanglement generation process involving memory channels. Here, we introduce a framework that captures entanglement distillation in the presence of natural correlations arising from memory channels. Conceptually, we bring together ideas from condensed-matter physics - that of renormalisation and of matrix-product states and operators - with those of local entanglement manipulation, Markov chain mixing, and quantum error correction. We identify meaningful parameter regions for which we prove convergence to maximally entangled states, arising as the fixed points of a matrix-product operator renormalisation flow.
Il valore ornamentale dell’albero: proposta metodologica per un nuovo percorso valutativo
Creators: name: Sardaro, Ruggiero
name: Panio, Daniela
name: Fucilli, Vincenzo
name: Bozzo, Francesco
name: Acciani, Claudio
Publisher: name: Aestimum
Year: 2017

description: In order to estimate the ornamental value of trees, many countries use specific parametric methods, which however are based on a subjective choice of parameters and assignment of respective weights. Aim of the paper is the overcoming of the above limits through the implementation of a different methodological path based on Choice Experiments. It allows the anchoring of the ornamental value to the utility that the community derives from the enjoyment of aesthetic, architectural, historical and cultural externalities of trees.
description: Aestimum, Aestimum 70 (2017)
Cord-Blood Transplants from Unrelated Donors in Patients with Hurler's Syndrome
Creators: name: Wenger, David A.
name: Allison-Thacker, June
name: Poe, Michele
name: Hopwood, John J.
name: Wood, Susan
name: Escolar, Maria L.
name: Staba, Susan L.
name: Szabolcs, Paul
name: Rubinstein, Pablo
name: Krivit, William
name: Kim, Young
name: Kurtzberg, Joanne
name: Martin, Paul L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: BACKGROUND Hurler's syndrome (the most severe form ofmucopolysaccharidosis type I) causes progressive deterioration ofthe central nervous system and death in childhood. Allogeneic bone marrow transplantation before the age oftwo years halts disease progression and prolongs life, but many children lack a bone marrow donor. We investigated the feasibility of using cord-blood transplants from unrelated donors and a myeloablative preparative regimen that did not involve total-body irradiation in young children with Hurler's syndrome. METHODS Between December 1995 and October 2002, 20 consecutive children with Hurler's syndrome received busulfan, cyclophosphamide, and antithymocyte globulin before receiving cord-blood transplants from unrelated donors. The children were subsequently evaluated for engraftment, adverse effects, and effects on disease symptoms. RESULTS Cord-blood donors had normal α-L-iduronidase activity (mean number of cells, 10.53×107per kilogram ofbody weight) and were discordant for up to three of six HLA markers. Neutrophil engraftment occurred a median of 24 days after transplantation. Five patients had grade II or grade III acute graft-versus-host disease; none had extensive chronic graft-versus-host disease. Seventeen ofthe 20 children were alive a median of 905 days after transplantation, with complete donor chimerism and normal peripheral-blood α-L-iduronidase activity (event-free survival rate, 85 percent). Transplantation improved neurocognitive performance and decreased somatic features of Hurler's syndrome. CONCLUSIONS Cord blood from unrelated donors appears to be an excellent source of stem cells for transplantation in patients with Hurler's syndrome. Sustained engraftment can be achieved without total-body irradiation. Cord-blood transplantation favorably altered the natural history of Hurler's syndrome and thus may be important to consider in young children with this form of the disease.
Dal turismo lineare al turismo circolare
Creators: name: Fusco Girard, Luigi
name: Nocca, Francesca
Publisher: name: Aestimum
Year: 2017

description: Tourism is the third largest socio-economic activity in the EU and thus it can be considered an engine for development, producing many positive impacts, from trade sector to employment. At the same time, it can produce many negative impacts because it is configured according to the model of linear economy. A deep analysis of impacts produced by tourism sector and its great potential in contributing to the achievement of SDGs are presented. The aim of this paper is to identify a tourism development/management model able to produce multidimensional benefits and, simultaneously, reduce (environmental, social and economic) costs. In this perspective, the circular economy is proposed as a model able to contribute to make tourism more sustainable. This model necessarily requires appropriate evaluation tools, indicators and knowledge.
description: Aestimum, Aestimum 70 (2017)
Dissecting holographic conductivities
Creators: name: Davison, Richard A.
name: Goutéraux, Blaise
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The DC thermoelectric conductivities of holographic systems in which translational symmetry is broken can be efficiently computed in terms of the near-horizon data of the dual black hole. By calculating the frequency dependent conductivities to the first subleading order in the momentum relaxation rate, we give a physical explanation for these conductivities in the simplest such example, in the limit of slow momentum relaxation. Specifically, we decompose each conductivity into the sum of a coherent contribution due to momentum relaxation and an incoherent contribution, due to intrinsic current relaxation. This decomposition is different from those previously proposed, and is consistent with the known hydrodynamic properties in the translationally invariant limit. This is the first step towards constructing a consistent theory of charged hydrodynamics with slow momentum relaxation.
description: v2: minor edits, matches published version. v1: 26 pages, 1 figure
Evaluation of irrigation resources for emergency drought situations in the production of the Conegliano Valdobbiadene Prosecco’s DOCG
Creators: name: Boatto, Vasco
name: Barisan, Luigino
name: Teo, Gianni
Publisher: name: Aestimum
Year: 2017

description: In viticulture, the management of water resources is a relevant issue in the profiles of a socio – economic, environmental sustainability policy turned to the development of the vine-growing territories with Designation of Origin. The paper has set itself the goal of an economic assessment on business decisions related to a drought risk in the Conegliano Valdobbiadene Prosecco DOCG, using the Bayesian methodology. The results showed the importance of an investment strategy that provides for the systematic introduction of emergency drought irrigation in the area DOCG’s vineyards which will guarantee the quality and the supply of the raw material, taking into account both the current evolution in marketing the product and the climate change scenarios.
description: Aestimum, Aestimum 70 (2017)
THE IMPLEMENTATION OF THE CODE STROKE PIT STOP: A QUALITY IMPROVEMENT PROJECT FOR GREATER EFFICIENCY
Creators: name: Helaine Kauffman
Publisher: name: Zenodo
Year: 2024
Subjects: large-vessel occlusion (LVO)
stroke
mechanical thrombectomy (MT)
nursing
code stroke pit stop
emergency department (ED)
stroke performance
systems-based process
quality improvement
access
emergency medical services (EMS)

description: Despite recent medical advancements to reduce the devastating morbidity and mortality outcomes commonly associated with ischemic stroke, there remains a disparity in access to these lifesaving interventions. The benefits of these advanced stroke interventions are profound and proven by the robust evidence in landmark studies conducted at high-performing academic medical institutions. However, the literature shows these interventions improve clinical outcomes when implemented by highly efficient systems-based processes. The code stroke process is the emergency department (ED) response system for acute stroke patients and the target area for streamlining quality improvement for efficient throughput to the appropriate intervention. This doctoral project aims to improve the efficiency of the stroke response process in the community hospital setting. The STAR module was applied to bridge the evidence into practice and nurture the needed cultural shift at the 377-bed community hospital. The optimized workflow was developed using the best evidence and shared experiences, and 12 ED quality/stroke nurses and approximately 60 ED staff nurses were trained. After implementing the optimized code stroke process, the desired outcomes were improved standard benchmark stroke performance data. The outcome performance data revealed overall improvement in performance and clinically significant improvement in stroke intervention performance. The successful implementation of an innovative code stroke process, called the code stroke pit stop, yields an opportunity to help drive improvement efforts at the community hospital setting seeking to advance the stroke program.
(1253) John Everard Upton
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Boundary conditions in hydrodynamic simulations of isolated galaxies and their impact on the gas-loss processes
Creators: name: Caproni, Anderson
name: Lanfranchi, Gustavo A.
name: Friaça, Amâncio C. S.
name: Soares, Jennifer F.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Three-dimensional hydrodynamic simulations are commonly used to study the evolution of the gaseous content in isolated galaxies, besides its connection with galactic star formation histories. Stellar winds, supernova blasts, and black hole feedback are mechanisms usually invoked to drive galactic outflows and decrease the initial galactic gas reservoir. However, any simulation imposes the need of choosing the limits of the simulated volume, which depends, for instance, on the size of the galaxy and the required numerical resolution, besides the available computational capability to perform it. In this work, we discuss the effects of boundary conditions on the evolution of the gas fraction in a small-sized galaxy (tidal radius of about 1 kpc), like classical spheroidal galaxies in the Local Group. We found that open boundaries with sizes smaller than approximately 10 times the characteristic radius of the galactic dark-matter halo become unappropriated for this kind of simulation after about 0.6 Gyr of evolution, since they act as an infinity reservoir of gas due to dark-matter gravity. We also tested two different boundary conditions that avoid gas accretion from numerical frontiers: closed and selective boundary conditions. Our results indicate that the later condition (that uses a velocity threshold criterion to open or close frontiers) is preferable since minimizes the number of reversed shocks due to closed boundaries. Although the strategy of putting computational frontiers as far as possible from the galaxy itself is always desirable, simulations with selective boundary condition can lead to similar results at lower computational costs.
description: 12 pages, 6 figures. Accepted for publication in The Astrophysical Journal
Improving Computer-aided Detection using Convolutional Neural Networks and Random View Aggregation
Creators: name: Roth, Holger R.
name: Lu, Le
name: Liu, Jiamin
name: Yao, Jianhua
name: Seff, Ari
name: Cherry, Kevin
name: Kim, Lauren
name: Summers, Ronald M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Automated computer-aided detection (CADe) in medical imaging has been an important tool in clinical practice and research. State-of-the-art methods often show high sensitivities but at the cost of high false-positives (FP) per patient rates. We design a two-tiered coarse-to-fine cascade framework that first operates a candidate generation system at sensitivities of $\sim$100% but at high FP levels. By leveraging existing CAD systems, coordinates of regions or volumes of interest (ROI or VOI) for lesion candidates are generated in this step and function as input for a second tier, which is our focus in this study. In this second stage, we generate $N$ 2D (two-dimensional) or 2.5D views via sampling through scale transformations, random translations and rotations with respect to each ROI's centroid coordinates. These random views are used to train deep convolutional neural network (ConvNet) classifiers. In testing, the trained ConvNets are employed to assign class (e.g., lesion, pathology) probabilities for a new set of $N$ random views that are then averaged at each ROI to compute a final per-candidate classification probability. This second tier behaves as a highly selective process to reject difficult false positives while preserving high sensitivities. The methods are evaluated on three different data sets with different numbers of patients: 59 patients for sclerotic metastases detection, 176 patients for lymph node detection, and 1,186 patients for colonic polyp detection. Experimental results show the ability of ConvNets to generalize well to different medical imaging CADe applications and scale elegantly to various data sets. Our proposed methods improve CADe performance markedly in all cases. CADe sensitivities improved from 57% to 70%, from 43% to 77% and from 58% to 75% at 3 FPs per patient for sclerotic metastases, lymph nodes and colonic polyps, respectively.
description: 2D vs 2.5D vs 3D inputs and comparison to other standard classifiers such as SVM have been addressed by more experimentation and two completely new sections and figures. Results and Discussions have been updated accordingly