cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
aWall: Agile Collaboration using Large Digital Multi-Touch Cardwalls
Creators: name: Anslow, Craig
name: Burkhard, Roger
name: Kropp, Martin
name: Mateescu, Magdalena
name: Vischi, Dario
name: Zahn, Carmen
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2016
Subjects: subject: software engineering
subject: agile methodologies
subject: team work
subject: collaborative workspace
subject: touch technology
subject: 005 - Computer Programmierung, Programme und Daten
subject: 631 - Technologie, Ausrüstung, Materialien
subject: 600 - Technik

description: Despite the availability of many digital agile board tools, most co-located agile software teams still use physical cardboards for their daily standup meetings. This is due to the fact that existing digital agile boards lacks supporting a collaborative workspace, direct interaction for the whole team in meetings, or making project information directly visible. In this paper we present aWall, a digital agile cardwall designed for the highly collaborative agile work style using large multi-touch wall displays. The effectiveness of aWall was evaluated in a user study with eleven software practitioners. Our findings indicate that aWall enables and encourages team work due to the large size of the wall, accessibility and visibility of large amounts of information, and possibility of customization of the interface. Based on this work, we suggest that augmenting digital cardwalls with large interactive touch technology and new interaction concepts is a useful way to support effective collaborative agile software development processes.
Application of Markowitz Portfolio Theory to Producing the World Major Field Crops
Creators: name: Vasylieva, Natalia
name: Vasylieva, Natalia
Publisher: name: Unknown
Year: 2020
Subjects: subject: Crop Production/Industries
subject: Risk and Uncertainty
subject: cereals and oilseeds
subject: risk
subject: production portfolio
subject: revenue forecast
subject: Markowitz models

description: Development of growing cereals and oilseeds is a pressing issue for providing global food security and renewable energy. The study deals with applying methods of portfolio theory to mitigate natural and marketing uncertainties emerged from unstable yields and volatile prices for wheat, maize, barley, sunflower, soybeans, and rapeseed. The research outcome based on the utilization of Markowitz mean-variance indicators made possible to evaluate portfolio performances of the world top cereals and oilseeds producers. The study findings at a country level combined econometric forecasting of the crop revenues and modeling optimal portfolios of cereals and oilseeds subject to acceptable trade-offs between risks and expected revenues. The fulfilled calculations with Ukrainian focus clarified farmland allocations under cereal and oilseed crops to underpin biodiversity and keep firm positions in the world markets.
Erstellung zweier Singles: Carry You - Dreaming
Creators: name: Imthurn, Gabriel
name: Steffen, David
name: Heimlicher, Matthias
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2016
Subjects: Musikproduktion

description: Coaching des Künstlers. Produktion von Musik mit Computertools mit dem Ziel zwei Singles zu veröffentlichen. Aufnahme und Korrektur der Stimme. Insgesamt Förderung eines jungen Talents und Zusammenarbeit mit einem Produzenten.
Erfolgsfaktoren und Hindernisse im Planungs- und Gestaltungsprozess flexibler Büroraumkonzepte
Creators: name: Feiler, Lara
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2019
Subjects: Mobil flexible Arbeit
FlexWork Phasenmodell
New Work Transformation
Arbeit 4.0
Büroraumgestaltung

description: Die vorliegende Masterarbeit untersucht förderliche und hinderliche Gestaltungselemente im Planungs- und Gestaltungsprozess flexibler Büroraumkonzepte und identifiziert Erfolgsfaktoren für deren Nutzung anhand der Dimensionen des FlexWork Phasenmodells. Die Erhebung der Daten umfasst zehn Experteninterviews, zwei Fallstudien und eine nicht-teilnehmenden Beobachtung. Die Untersuchungsteilnehmer sind Berater für Büroraumgestaltung, interne Projektleiter und Projektteam-Mitglieder von Unternehmen, die sich in unterschiedlichen Phasen des Transformationsprozesses befinden. Es konnten drei Gruppen mit unterschiedlicher Wirkung identifiziert werden. Rein hinderliche Faktoren wirken sich bei Nicht-Befolgung hinderlich auf den Prozess aus. Rein förderliche Faktoren wirken sich ausschliesslich förderlich auf den Prozess aus und förderliche und gleichzeitig hinderliche Faktoren entfalten je nach Umgang eine förderliche oder hinderliche Wirkung auf den Prozess. Als Einflussfaktoren für die Nutzung flexibler Büroräume gelten Funktionalität, Identität /Teamheimat, Raumkompetenz, Evaluation / Weiterentwicklung, funktionierende technische Infrastruktur, Passung zur Unternehmensstruktur und -kultur und Selbstselektion.
Additional file 1 of Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway
Creators: name: Xu, Xin
name: Gao, Weiwei
name: Li, Lei
name: Hao, Jiheng
name: Yang, Bin
name: Wang, Tao
name: Li, Long
name: Bai, Xuesong
name: Li, Fanjian
name: Ren, Honglei
name: Zhang, Meng
name: Zhang, Liyong
name: Wang, Jiyue
name: Wang, Dong
name: Zhang, Jianning
name: Jiao, Liqun
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Neuroscience
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Supplemental Table 1. Baseline characteristics of the participants.
Implementation of a human renal proximal tubule on a chip for nephrotoxicity and drug interaction studies
Creators: name: Suter-Dick, Laura
name: Caj, Michaela
name: Hutter, Simon
name: Vormann, Marianne
name: Vriend, Jelle
name: Lanz, Henriette
name: Gijzen, Linda
name: Van Den Heuvel, Angelique
name: Joore, Jos
name: Trietsch, Sebastian
name: Stuut, Christaan
name: Nieskens, Tom T.G.
name: Peters, Janny
name: Ramp, Daniela
name: Russel, Frans
name: Roth, Adrian
name: Lu, Shuyan
name: Polli, Joseph
name: Jacobsen, Björn
Publisher: name: Elsevier
Year: 2021
Subjects: Renal-proximal-tubule-on-a-chip
Drug-screening
Drug-transporter interaction
miRNA
Microfluidics
Pharmaceutical

description: Proximal tubule epithelial cells (PTEC) are susceptible to drug-induced kidney injury (DIKI). Cell-based, two-dimensional (2D) in vitro PTEC models are often poor predictors of DIKI, probably due to the lack of physiological architecture and flow. Here, we assessed a high throughput, 3D microfluidic platform (Nephroscreen) for the detection of DIKI in pharmaceutical development. This system was established with four model nephrotoxic drugs (cisplatin, tenofovir, tobramycin and cyclosporin A) and tested with eight pharmaceutical compounds. Measured parameters included cell viability, release of lactate dehydrogenase (LDH) and N-acetyl-β-d-glucosaminidase (NAG), barrier integrity, release of specific miRNAs, and gene expression of toxicity markers. Drug-transporter interactions for P-gp and MRP2/4 were also determined. The most predictive read outs for DIKI were a combination of cell viability, LDH and miRNA release. In conclusion, Nephroscreen detected DIKI in a robust manner, is compatible with automated pipetting, proved to be amenable to long-term experiments, and was easily transferred between laboratories. This proof-of-concept-study demonstrated the usability and reproducibility of Nephroscreen for the detection of DIKI and drug-transporter interactions. Nephroscreen it represents a valuable tool towards replacing animal testing and supporting the 3Rs (Reduce, Refine and Replace animal experimentation).
Enteric-coated budesonide for the induction and maintenance of remission of Crohn’s disease in children
Creators: name: Cohen, Stanley A.
name: Aloi, Marina
name: Arumugam, Ramalingam
name: Baker, Robert
name: Bax, Kevin
name: Jaroslaw Kierkuś
name: Koletzko, Sibylle
name: Lionetti, Paolo
name: Persson, Tore
name: Eklund, Stefan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Objective: These studies evaluated the safety and efficacy of enteric-coated budesonide for the induction and maintenance of remission of mild-to-moderate Crohn’s disease (CD) in children. Methods: The consecutive, multicenter, open-label, non-comparative studies enrolled patients aged 6–17 years. In the induction study, patients with active CD of the ileum and/or ascending colon received budesonide 9 mg or 6 mg once daily for 8 weeks; in the maintenance study, patients in remission received budesonide 6 mg once daily for 12 weeks. The primary objective was assessment of safety, including glucocorticosteroid-related side effects and serum cortisol levels. Efficacy was assessed using the Pediatric Crohn’s Disease Activity Index (PCDAI), and health-related quality of life (HRQoL) using the IMPACT-III questionnaire. Results: In the induction study (n = 108), most adverse events were related to CD, commonly abdominal pain; possible glucocorticosteroid-related effects included acne and increased appetite but without significant weight gain. Subnormal morning cortisol levels were observed in 32 of 103 patients after 8 weeks. Budesonide reduced disease activity from baseline (mean ± standard deviation, 9.1 ± 8.5 vs. 19.1 ± 10.1, p p n = 50), mean disease activity worsened (p = .047) with HRQoL unchanged (p = .33). Conclusions: Budesonide treatment was generally well tolerated, although the potential for adrenal suppression was noted. Budesonide was effective for induction of remission in children with mild-to-moderate CD but not for maintaining remission (ClinicalTrials.gov identifiers: NCT01444092, NCT01453946).
Additional file 2 of Extracellular vesicles-based pre-targeting strategy enables multi-modal imaging of orthotopic colon cancer and image-guided surgery
Creators: name: Jing, Boping
name: Qian, Ruijie
name: Jiang, Dawei
name: Gai, Yongkang
name: Liu, Zhen
name: Guo, Feng
name: Ren, Sen
name: Gao, Yu
name: Lan, Xiaoli
name: An, Rui
Publisher: name: figshare
Year: 2021
Subjects: Biochemistry
Space Science
Medicine
Cell Biology
Biotechnology
Chemical Sciences not elsewhere classified
Science Policy
Biological Sciences not elsewhere classified
Cancer

description: Additional file 2: Figure S1. Radiolabeling efficiency and stability. A The radiolabeling efficiencies of 68Ga-L-NETA-DBCO. B The stability of 68Ga-L-NETA-DBCO. Figure S2. PET imaging of the control group. A Representative static PET images at 1 h after the injection of 68Ga-L-NETA-DBCO. B Representative static PET images at 2 h after the injection of 68Ga-L-NETA-DBCO. White arrows point the tumor sites. Table S1 The HCT116 cell and ADSCs after 24 h incubation with ADSCs-EV at different concentrations (μg/mL). Bars represent means ± SD (n = 4). Table S2. The HCT116 cell and adipose stem cell viability after incubation with ADSCs-EV at different time points (h). Bars represent means ± SD (n = 4). Table S3. The HCT116 cell and adipose stem cell viability after incubation with 68Ga-L-NETA-DBCO at different time points (h). Bars represent means ± SD (n = 4).
Sind Hochhäuser als Nullenergiegebäude machbar?
Creators: name: Hall, Monika
name: Geissler, Achim
Publisher: name: Passivhaus Institut
Year: 2016
Subjects: Hochhäuser mit PV-Fassade
Nullenergie
Nullwärmeenergie
Nullenergiegebäude

description: Für Einfamilienhäuser und kleine Mehrfamiliengebäude reicht in der Regel der Platz für eine entsprechend grosse Photovoltaikanlage auf dem Dach aus, um in der Jahresbilanz den Gesamtenergiebedarf durch den Photovoltaikertrag zu decken. Es stellt sich die Frage, ob grosse Gebäude, d.h. Gebäude bis zu 40 Stockwerken, mit langgestrecktem bzw. quadratischem Grundriss genügend Fläche für Photovoltaik zur Verfügung stellen können, so dass eine Nullbilanz für die gesamte Gebäudetechnik (HWLK-Nullbilanz "Nullwärmeenergiegebäude") oder den Gesamtenergiebedarf des Gebäudes (GEB-Nullbilanz "Nullenergiegebäude") im Jahr erreicht werden kann.
Directional Control of Weight Forces in Rotating Bodies
Creators: name: Aquino, Fran De
Publisher: name: figshare
Year: 2017
Subjects: Applied Physics

description: The frame-dragging effect tells us that when a body rotates around itself the metric of spacetime around its surface is dragged. This occurs, for example, in the metric of the spacetime around the Earth surface, and produces the well-known phenomenon of shifting of the orbits of the satellites near the Earth. Such as the orbits of the satellites, the force lines of the gravitational field produced by rotating bodies are also affected by the frame-dragging effect. This means that the direction of a gravitational central force in a rotating body should be radially displaced, in respect to their initial position. In this work, we show that the radial displacement angle depends on the angular velocity of the rotating body, and that this fact point to the possibility of controlling the direction of these gravitational central forces, simply by controlling the angular velocity of the rotating body.
Διαγνωστικές Προσεγγίσεις στη Λογοπαθολογία [Assessment in Speech – Language Pathology]
Creators: name: Tafiadis, Dionysios
name: Eleanna Virvidakis
Publisher: name: figshare
Year: 2017
Subjects: subject: 170204 Linguistic Processes (incl. Speech Production and Comprehension)
subject: FOS: Psychology

description: Edited and Translated in Greek of the Book: Assessment in Speech – Language Pathology

Greek ISBN: 978-960-9427-30-2
Do attributions matter when task conflict becomes personal?
Creators: name: Vollmer, Albert
name: Vetter, Ariane
Publisher: name: International Association for Conflict Management
Year: 2019
Subjects: subject: Conflict
subject: Attribution
subject: Psychological Health
subject: 330 - Wirtschaft
subject: 150 - Psychologie
subject: 370 - Erziehung, Schul- und Bildungswesen

description: When agile teams attribute their task conflict to characteristics of their group members and their interactions, they experience more relationship conflicts and perceive their job as less manageable, meaningful and comprehensible.
High-yield factors in the new soybean cultivar ‘Soramizuki’ derived from a US parent cultivar
Creators: name: Yamazaki, Ryo
name: Nanjo, Yohei
name: Saruta, Masayasu
name: Kato, Shin
name: Hirata, Kaori
name: Nakashima, Kenta
name: Takeshima, Ryoma
name: Takahashi, Koji
name: Aoki, Emiko
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: A new soybean cultivar, ‘Soramizuki,’ was developed by crossing ‘Fukuyutaka A1 gou’ with ‘UA4805’ to integrate the high-yield characteristics of a US cultivar into a Japanese cultivar. While the high yield and yield stability of ‘Soramizuki’ have been confirmed, the specific high-yielding factors were previously unknown. This study compared the yield and yield components of ‘Soramizuki,’ ‘UA4805,’ and ‘Sachiyutaka A1 gou’ in experimental fields during 2021 and 2023. In these two-year experiments, ‘Soramizuki’ demonstrated a significantly higher yield than ‘Sachiyutaka A1 gou.’ Despite a significant yield decrease in ‘UA4805’ in 2023 due to stink bug damage, it showed the highest yield among the three cultivars in 2021. Both ‘Soramizuki’ and ‘UA4805’ exhibited more total nodes, pods per node, and seeds per pod compared to ‘Sachiyutaka A1 gou.’ These differences were attributed to a higher node increase rate, a larger number of blooms per node, and a higher ratio of pods with three seed cavities. Additionally, ‘Soramizuki’ and ‘UA4805’ had greater dry matter weight per plant than ‘Sachiyutaka A1 gou,’ though there were no variations in the harvest index. The light interception ratio per leaf area in the upper canopy was lower in both ‘Soramizuki’ and ‘UA4805.’ These results suggest that the high-yielding traits of ‘Soramizuki’ are derived from the US cultivar ‘UA4805.’
Οδηγός Σχεδιασμού Λογοθεραπευτικής Παρέμβασης [The Speech – Language Pathology Treatment Planner]
Creators: name: Tafiadis, Dionysios
name: Diomides Psomopoulos
Publisher: name: figshare
Year: 2017
Subjects: subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature

description: Edited and Translated in Greek of the Book: The Speech – Language Pathology Treatment Planner

Greek ISBN: 978-960-98421-5-0
Robustness assessment of clinical adaptive proton and photon radiotherapy for oesophageal cancer in the model-based approach
Creators: name: Visser, Sabine
name: O. Ribeiro, Cássia
name: Dieters, Margriet
name: Mul, Veronique E.
name: Niezink, Anne G.H.
name: Van Der Schaaf, Arjen
name: Langendijk, Johannes A.
name: Korevaar, Erik W.
name: Both, Stefan
name: Muijs, Christina T.
name: Knopf, Antje
Publisher: name: Elsevier
Year: 2022
Subjects: subject: IMPT
subject: VMAT
subject: Robustness
subject: Oesophageal cancer
subject: Dose accumulation
subject: Model-based approach
subject: 600 - Technik, Medizin, angewandte Wissenschaften

description: Purpose In the Netherlands, oesophageal cancer (EC) patients are selected for intensity modulated proton therapy (IMPT) using the expected normal tissue complication probability reduction (ΔNTCP) when treating with IMPT compared to volumetric modulated arc therapy (VMAT). In this study, we evaluate the robustness of the first EC patients treated with IMPT in our clinic in terms of target and organs-at-risk (OAR) dose with corresponding NTCP, as compared to VMAT. Materials and Methods For 20 consecutive EC patients, clinical IMPT and VMAT plans were created on the average planning 4DCT. Both plans were robustly evaluated on weekly repeated 4DCTs and if target coverage degraded, replanning was performed. Target coverage was evaluated for complete treatment trajectories with and without replanning. The planned and accumulated mean lung dose (MLD) and mean heart dose (MHD) were additionally evaluated and translated into NTCP. Results Replanning in the clinic was performed more often for IMPT (15x) than would have been needed for VMAT (8x) (p = 0.11). Both adaptive treatments would have resulted in adequate accumulated target dose coverage. Replanning in the first week of treatment had most clinical impact, as anatomical changes resulting in insufficient accumulated target coverage were already observed at this stage. No differences were found in MLD between the planned dose and the accumulated dose. Accumulated MHD differed from the planned dose (p < 0.001), but since these differences were similar for VMAT and IMPT (1.0 and 1.5 Gy, respectively), the ΔNTCP remained unchanged. Conclusion Following an adaptive clinical workflow, adequate target dose coverage and stable OAR doses with corresponding NTCPs was assured for both IMPT and VMAT.
Chancen und Herausforderungen von onlinebasierten Studienwahlassistenten
Creators: name: Pässler, Katja
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2021

description: Onlinebasierte Studienwahlassistenten oder Online-Self-Assessments wurden entwickelt, um Schülerinnen und Schülern bei ihrer Studienwahl zu unterstützen. Studien zeigen, dass durch die Bearbeitung von Self-Assessments die studienwahlbezogene Selbstwirksamkeit, das Wissen über studienbezogene Anforderungen sowie die Selbstkenntnis erhöht werden. Allerdings unterscheiden sich die Angebote deutlich in ihrer Qualität, Aktualität und Zielstellung. Im Workshop wird ein Überblick über die verschiedenen Angebote gegeben und Kriterien zur Evaluation von Online-Self-Assessments vorgestellt. Ausserdem werden Chancen und Risiken von Self-Assessments diskutiert und die Frage erörtert, wie Self-Assessments mit anderen Informations- und Beratungsangeboten sinnvoll kombiniert werden können.
Application of the diagnostic tool EFA-4 in MCI patients. [Proceeding]
Creators: name: Alexiou Ioulia
name: Nasios Grigorios
name: Tafiadis, Dionysios
name: Tsolaki Magda
name: Erkotidou Eleni
Publisher: name: figshare
Year: 2017
Subjects: Neuroscience

description: Proceedings in Greek @ 9th Panhellenic Conference on Alzheimer's Disease and Related Disorders and 1st Mediterranean Conference on Neurodegenerative Diseases
Lonely sensational icons: semantic neighbourhood density, sensory experience and iconicity
Creators: name: Sidhu, David M.
name: Pexman, Penny M.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Perry, Perlman, and Lupyan (2015. Iconicity in English and Spanish and its relation to lexical category and age of acquisition. PLoS One, 10, e0137147. doi:10.1371/journal.pone.0137147) found that a sample of English words was rated as being slightly iconic, on average, with words varying in their iconicity. Thus, the relationship between word form and meaning does not seem to be categorically arbitrary. We investigated factors that might explain variation in iconicity: specifically, that concepts with sparser semantic neighbourhoods have more iconic word forms, and that concepts with more sensory information are more likely to have iconic word forms (as in Winter, Perlman, Perry, & Lupyan, in press. Which words are the most iconic? Iconicity in English sensory words. Interaction Studies. Retrieved from http://sapir.psych.wisc.edu/papers/winter_perlman_perry_lupyan_interaction-studies.pdf), even after accounting for age of acquisition (AoA; Kuperman, Stadthagen-Gonzalez, & Brysbaert, 2012. Age-of-acquisition ratings for 30,000 English words. Behavior Research Methods, 44, 978–990. doi:10.3758/s13428-012-0210-4). We found support for both predictions: words with sparser semantic neighbourhoods (ARC; Shaoul & Westbury, 2010. Exploring lexical co-occurrence space using HiDEx. Behavior Research Methods, 42, 393–413. doi:10.3758/Brm.42.2.393), and greater associated sensory experience (SER; Juhasz & Yap, 2013. Sensory experience ratings for over 5,000 mono-and disyllabic words. Behavior Research Methods, 45, 160–168. doi:10.3758/s13428-012-0242-9), were more iconic, even after accounting for AoA. ARC was also found to moderate SER. These results further our appreciation of iconicity as a general property of the lexicon.
On the low-cycle fatigue behavior of thermo-mechanically processed high-strength aluminum alloys
Creators: name: Sajadifar, Seyed Vahid
name: Scharifi, Emad
name: Wegener, Thomas
name: Krochmal, Marcel
name: Lotz, Steffen
name: Steinhoff, Kurt
name: Niendorf, Thomas
Publisher: name: Universität Kassel
Year: 2021
Subjects: subject: high-strength aluminum alloys
subject: low-cycle fatique
subject: thermo-mechanical processing
subject: microstructure
subject: fracture
subject: 600
subject: 620
subject: Aluminiumlegierung
subject: Ermüdung bei niedrigen Lastspielzahlen
subject: Thermomechanische Behandlung
subject: Mechanische Eigenschaft
subject: Mikrostruktur
subject: Bruch
subject: Materialermüdung

description: © This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
Stateful View Controllers in iOS
Creators: name: Dietsche, Moritz
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2013
Subjects: subject: Zustandsbasierte Benutzungsschnittstelle
subject: iOS
subject: State Pattern
subject: 600 - Technik
subject: 005 - Computer Programmierung, Programme und Daten

description: Für die Entwicklung einer zustandsbasierte Benutzungsschittstelle eines mobilen Gerätes zeigen wir drei verschiedene Ansätze auf. Wir vergleichen die Ansätze miteinander und führen einen Ansatz genauer aus, welchen wir im Rahmen der Entwicklung eines Störmeldesystems auf dem iPhone entwickelt haben. Dieser Ansatz basiert auf dem State Pattern und verwendet eine einzige einfache tabellarische Darstellung, welche dynamisch mit den zustandsabhängigen Elementen eingefüllt wird.
Einfluss von VDC auf Projektabwicklungsmethoden
Creators: name: Ager, Elisabeth
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2018
Subjects: BIM
VDC

description: Die konventionellen Bauprojektabwicklungsmodelle sind veraltet und können die Optimierung der neuen Methodik durch Virtual Design & Construction behindern oder verlangsamen. Integrierte Organisations- und Abwicklungsansätze zeigen klare Mehrwerte für alle Stakeholder auf. Jedes Projekt ist ein Unikat und Bedarf unterschiedlicher Voraussetzungen.
Numerical Computation of the Transfer Functions of an Axisymmetric Duct with the Extended Discrete Singular Convolution Method
Creators: name: Taillard, Pierre-André
name: Hélie, Thomas
name: Bensoam, Joël
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2014
Subjects: Musical acoustics

description: This work takes part of the "cagima" project (supported by the ANR) which investigates the defects of the tuning of reed musical instruments as well as their homogeneity of emission and timbre. The goal consists in replacing the traditional approach adopted by instrument makers by a global and rational approach in the design of new instruments /ab initio/ (called "logical instruments"), minimizing some identi ed defects. In this context, an interactive virtual model, predictive and con gurable is proposed. Several approaches are available in the literature but the main di culty is to design digital instruments that are accurate (according to measurements) and that can be implemented in real-time. In this paper, an approach based on the Extended Discrete Singular Convolution method (EDSC) is proposed. The temporal operator (including the fractional derivative term for viscothermal losses) is implemented according to the EDSC formalism. The method allows a fast, straightforward and accurate computation of the transfer functions of an axisymmetric duct with an arbitrary pro le. The computation of the case where the losses are dependent from the diameter causes no noticeable di culty. The results are compared to measurements of a trombone bell.
Goodyschle A, a new butenolide with significant BchE inhibitory activity from Goodyera schlechtendaliana
Creators: name: Dai, Le-Yao
name: Yin, Qi-Meng
name: Qiu, Jia-Kai
name: Zhang, Zhen-Yang
name: Li, Gang
name: Huang, Meng-Ni
name: Liu, Liang
Publisher: name: Taylor & Francis
Year: 2020
Subjects: Biochemistry
Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer

description: Goodyschle A (1), a new butenolide, was isolated from the whole grass of Goodyera schlechtendaliana, an orchidaceous edible medicinal plant. The structure of the new compound was elucidated by 1 D and 2 D NMR experiments in addition to HRESIMS analyses. Compound 1 was evaluated for its bioactivities including cytotoxic activity against human gastric cancer (SGC-7901) and human hepatocellular carcinoma (HepG2) cell lines, inhibitory activity on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), and DPPH radical scavenging activity. As a result, compound 1 showed potent BChE inhibitory activity (IC50 value = 6.88 ± 1.63 μM), moderate DPPH radical scavenging activity (IC50 value = 16.25 ± 0.21 μM), and slight AChE inhibitory and cytotoxic activities. These findings suggest that compound 1 is worthy for further investigations in terms of its selective BChE inhibitory activity.
Application of the diagnostic tool EFA-4in MCI patients
Creators: name: Alexiou Ioulia
name: Nasios Grigorios
name: Tafiadis, Dionysios
name: Tsolaki Magda
name: Erkotidou Eleni
Publisher: name: figshare
Year: 2017
Subjects: Neuroscience

description: Proceedings in Greek @ 10th Panhellenic Conference on Alzheimer's Disease and Related Disorders and 2nd Mediterranean Conference on Neurodegenerative Diseases
Periphere Epitheliale Corneale Hypertrophie (PECH) beim Tragen weicher hydrophiler Kontaktlinsen
Creators: name: Bronner, Rainer
name: Nosch, Daniela
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2016
Subjects: Cornea
Hypertrophie
Kontaktlinse
Hypoxie

description: Peripheral epithelial corneal hyperfluorescence (PECH) in daily soft contact lens (CL) wear is described by three case reports. In vivo confocal microscopy (IVCM) measurements show the presence of epithelial corneal hypertrophy on affected eyes. A statistical analysis of a group of patients with PECH in comparison to a control group suggests a hypoxic cause for PECH. Further clinical studies with balanced patient populations are required to confirm these findings, as the population of this study group was affected by a selection bias.
Geology of the Saint-Marcel valley metaophiolites (Northwestern Alps, Italy)
Creators: name: Tartarotti, Paola
name: Martin, Silvana
name: Monopoli, Bruno
name: Benciolini, Luca
name: Schiavo, Alessio
name: Campana, Riccardo
name: Vigni, Irene
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The geological map of the Saint-Marcel valley at the scale of 1:20,000 illustrates the tectonic setting of metaophiolites from the southern Aosta Valley, in the Italian side of the Western Alpine belt. The map highlights the sharp contact between the metaophiolitic basement and its metasedimentary cover, which mainly consists of quartzites, marbles, and calcschists. In spite of the Alpine tectonics, this contact is regarded as deriving from the original oceanic crust/sediments interface. Metaophiolites mostly consist of metabasalts hosting Fe–Cu sulphide mineralisations, characterised by high-pressure metamorphic imprint. These rocks likely represent the shallowest portion of the Tethyan oceanic lithosphere created near the axis of the slow-spreading ridge where hydrothermal fluid circulation was active. Selected key-sections through metasediments reveal a consistent internal lithostratigraphy, in spite of the pervasive metamorphic and tectonic reworking acting during the Alpine evolution. Metasediments reflect various sedimentation episodes starting from pelagic and proximal settings to the onset of the orogenic stage. The Saint-Marcel valley metasediments thus reflect a changing in the sedimentation environments through time and space during the overall geologic evolution.
Practical and efficient synthesis of gefitinib through selective O-alkylation: A novel concept for a transient protection group
Creators: name: Kang, Sung Kwon
name: Lee, Seung Wook
name: Daekoo Woo
name: Jaehoon Sim
name: Young-Ger Suh
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: A practical process that includes a simple four-step procedure for the preparation of gefitinib (1), a tyrosine kinase inhibitor that targets the epidermal growth factor receptor, is described. Dramatic improvements over previously reported conventional synthetic procedures were achieved. We found effective coupling conditions to minimize the inevitable production of an N-alkylated side product, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)-quinazoline-4-amine (3) using a transient trimethylsilyl protecting group. We synthesized gefitinib in an 81.1% overall yield from a commercially available starting material on a multigram scale using a route that did not require work-up of any of the reaction steps.
Differentially localized rice ethylene receptors OsERS1 and OsETR2 and their potential role during submergence
Creators: name: Yu, Manda
name: Yau, Chi Ping
name: Yip, Wing Kin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Plant Biology

description: Ethylene is gaseous plant hormone that controls a variety of physiologic activities. OsERS1 and OsETR2 are major ethylene receptors in rice that have been reported to have different regulatory functions. The GFP fused N-terminus of OsERS1 and OsETR2 showed differentially localization patterns when transiently expressed in onion epidermal cells. Base on these results, we suggested that OsERS1 could be localized to plasma membranes, whereas OsETR2 could be localized to the endoplasmic reticulum. Furthermore, instead of the constitutive expression profile of OsERS1, OsETR2 is differentially expressed in seedlings of light/dark-grown conditions, submergence or exogenous ethylene treatments. Our results and others support the notion that OsERS1 and OsETR2 could have different roles during rice plant submergence.
Entwicklung des Wohlbefindens von Mitarbeitenden bei der Einführung von Tablets in der Produktion
Creators: name: Ingold, Pascale
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2019
Subjects: Digitalisierung
Stress
Belastung
Beanspruchungsfolgen
Produktion
Tablet
Wohlbefinden
Ressourcen
digitale Arbeitsmittel
Informations- und Kommunikations-technologie

description: Neue Technologien und digitale Arbeitsmittel prägen die gegenwärtige Produktionsbranche. Deshalb soll bei den Schweizerischen Bundesbahnen varianzanalytisch untersucht werden, wie sich das Wohlbefinden von Produktionsmitarbeitenden bei der Einführung von Tablets entwickelt und welchen Einfluss gesundheitsförderliche Ressourcen haben. Die Fragestel-lungen werden in einer quantitativen Längsschnittstudie über drei Monate bei 58 Mitarbeiten-den analysiert. Die gewonnenen Ergebnisse lassen einen positiven Trend in der Zunahme der emotionalen Erschöpfung erkennen (p=.053, η2p=.05). Darüber hinaus konnte gezeigt werden, dass alle untersuchten Ressourcen einen positiven Einfluss auf Wohlbefindenskomponenten haben (Effekte zw. η2p=.05 und .25) und dass die Ressourcen Kompetenzen und Erfahrung sowie Benutzerfreundlichkeit mit der Entwicklung von Wohlbefindenskomponenten bei der Einfüh-rung von Tablets interagieren (Effekte zw. η2p=.05 und .07). Die Ergebnisse verdeutlichen, dass die betriebliche Gesundheitsförderung Massnahmen auf unterschiedlichen Ebenen verfolgen sollte (u.a. Förderung der Kompetenzen, Optimierung der Benutzerfreundlichkeit und Gewährleistung von sozialer Unterstützung).
D6.4 Impact Assessment Report V2
Creators: name: Passani, Antonella
name: Annelli Janssen
name: Forino, Giuseppe
name: Di Lisio, Giulia
Publisher: name: Zenodo
Year: 2022
Subjects: Impact assessment
impact of CS projects
social impact
economic impact
scientific impact
environmental impact
policy impact
transformative potential of CS projects

description: This document reports the results of the impact assessment of the ACTION project considering the entire duration of the project. Following the ACTION impact assessment methodology (D6.1) the main areas of impact considered are: scientific, social, economic, political and environmental. The transformative potential of the pilots is also considered together with their potential contribution to UN Sustainable Development Goals (SDGs). The areas of impact that score highest are the scientific and the social ones and promising results are observable also in terms of political impact
Des Observatoires et Planétariums: Réflexions Autour de Julio Cortázar et Jeronimo Voss
Creators: name: Klengel, Susanne
Publisher: name: Honoré Champion
Year: 2019
Subjects: Louis Auguste Blanqui

description: Les essais ici réunis, issus d’un colloque tenu à la Bibliothèque nationale de France et à la Maison de l’Amérique latine, à Paris, s’attachent à Blanqui, à son Éternité par les astres, et à son hypothèse astronomique fort éloignée de son radicalisme révolutionnaire. Prenant acte du fait qu’au XIXe siècle, on conciliait l’intérêt pour la recherche astronomique et la fiction, les connaissances les plus méthodiques et les rêves prophétiques, ils proposent une lecture en grande partie approbatrice de Blanqui et de son monde imaginé – répétitions, reproductions, copies et sosies promettent ou compromettent une forme d’éternité, une éternité sub specie d’une postérité dans un autre lieu, un autre milieu, un autre espace – qu’on peut voir comme contemporains et informatiques. L’Éternité par les astres, ainsi relue, conserve une pertinence cognitive, politique et esthétique.
Application of the diagnostic tool EFA-4in MCI patients. [Proceeding]
Creators: name: Alexiou Ioulia
name: Nasios Grigorios
name: Tafiadis, Dionysios
name: Tsolaki Magda
name: Erkotidou Eleni
Publisher: name: figshare
Year: 2017
Subjects: Neuroscience

description: Proceedings in Greek @ 9th Panhellenic Conference on Alzheimer's Disease and Related Disorders and 1st Mediterranean Conference on Neurodegenerative Diseases
Additional file 1 of Dietary L-citrulline supplementation modulates nitric oxide synthesis and anti-oxidant status of laying hens during summer season
Creators: name: Uyanga, Victoria A.
name: Jiao, Hongchao
name: Zhao, Jingpeng
name: Wang, Xiaojuan
name: Lin, Hai
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Additional file 1: Fig. S1. Effect of different L-Cit supplementation levels on weekly rectal temperatures of laying hens. Values are means ± SEM. (n = 12 birds).
TET1 deficiency attenuates the DNA damage response and promotes resistance to DNA damaging agents
Creators: name: Coulter, Jonathan B.
name: Lopez-Bertoni, Hernando
name: Kuhns, Katherine J.
name: Lee, Richard S.
name: Laterra, John
name: Bressler, Joseph P.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Recent studies have shown that loss of TET1 may play a significant role in the formation of tumors. Because genomic instability is a hallmark of cancer, we examined the potential involvement of 10-11 translocation 1 (TET1) in the DNA damage response (DDR). Here we demonstrate that, in response to clinically relevant doses of ionizing radiation (IR), human glial cells made TET1-deficient with lentiviral vectors displayed greater numbers of colony forming units and lower levels of apoptotic markers compared with glial cells transduced with control vectors; yet, they harbored greater DNA strand breaks. The G2/M check point and expression of cyclin B1 were greatly diminished in TET1-deficient cells, and TET1-deficient cells displayed lower levels of γH2A.x following exposure to IR. Levels of DNA-PKcs, which are DNA-PK complex members, were lower in TET1-deficient cells compared with control cell lines. However, levels of ATM were similar in both cell lines. Cyclin B1, DNA-PKcs, and γH2A.x levels were each rescued by reintroduction of the TET1 catalytic domain. Finally, cytosine methylation within intron 1 of PRKDC, the gene encoding DNA-PKcs, was significantly higher upon depletion of TET1. Taken together, this study illustrates the involvement of TET1 in the different arms of the DDR and suggests its loss results in the continued survival of cells with genomic instability.
title: Robust loss functions for machine learning in the presence of noisy labels
Creators: name: Toner, William
Publisher: name: The University of Edinburgh
Year: 2025
Subjects: subject: Robust loss functions
subject: Noisy labels
subject: Overfitting
subject: Label noise rate
subject: Noise-tolerant

description: Over the last decade, there has been a significant improvement in machine learning methods for classification, particularly in computer vision. This progress has increased the demand for large labelled datasets. However, obtaining clean, accurately labelled datasets on the required scale can be prohibitively expensive. Consequently, practitioners often resort to methods that yield larger datasets but with substantial label noise, such as web querying or crowd-sourcing. Even conventional data collection methods can introduce errors due to human fallibility, particularly in complex domains like medical imaging. While broadly beneficial, the high expressibility of neural network classifiers renders them prone to overfitting on noisy labels. This issue can severely impact model performance and generalisation, leading to significant setbacks in practical applications. The challenge of noisy labels has sparked substantial interest in developing methodologies robust to such conditions. Among various strategies for handling noisy labels, ‘robust loss functions’ have emerged as a favoured method due to their simplicity and effectiveness. Despite extensive research, important theoretical gaps in understanding robust loss functions persist. Moreover, a disconnect between the theory and practice of these functions remains. As a result, there is an ongoing lack of principled yet simple and computationally economical loss-based approaches for learning in the presence of noisy labels. This thesis addresses these challenges. We show how overfitting can be curbed by lower-bounding the training loss, motivating this loss-bounding policy theoretically. We derive the relevant lower bound, showing how it can be estimated via the label noise rate. We also develop a straightforward early-stopping policy that operates without knowledge of the noise rate or access to a cleanly-labelled validation set. We validate the effectiveness of our approaches through extensive experiments across various noisily-labelled benchmark datasets. We build on and generalise the existing theory of noise-tolerant loss functions, demonstrating that such loss functions are rare and do not exist for most noise models. This work provides important theoretical insights and establishes conditions under which a loss function can be considered noise-tolerant. Our final chapter describes how GANs can be conceptualised in terms of noisy labels, deriving a novel loss function and providing both theoretical insights and experimental results.
Additional file 4 of Dietary L-citrulline supplementation modulates nitric oxide synthesis and anti-oxidant status of laying hens during summer season
Creators: name: Uyanga, Victoria A.
name: Jiao, Hongchao
name: Zhao, Jingpeng
name: Wang, Xiaojuan
name: Lin, Hai
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Additional file 4: Table S2. Quadratic regression model for laying rate as a function of dietary citrulline levels in laying hens at 34–42 weeks old.
Practical and efficient synthesis of gefitinib via selective O-alkylation: A novel concept for a transient protection group
Creators: name: Kang, Sung Kwon
name: Lee, Seung Wook
name: Daekoo Woo
name: Jaehoon Sim
name: Young-Ger Suh
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: A practical process that includes a simple four-step procedure for the preparation of gefitinib (1), a tyrosine kinase inhibitor that targets the epidermal growth factor receptor, is described. Dramatic improvements over previously reported conventional synthetic procedures were achieved. We found effective coupling conditions to minimize the inevitable production of an N-alkylated side product, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)-quinazoline-4-amine (3) by using a transient trimethylsilyl protecting group. We synthesized gefitinib in an 81.1% overall yield from a commercially available starting material on a multigram scale using a route that did not require work-up of any of the reaction steps.
‘Products Mapping’ of South Africa’s Agri-food trade with the EU28 and Africa
Creators: name: Zdráhal, Ivo
name: Verter, Nahanga
name: Lategan, Francois
name: Zdráhal, Ivo
name: Verter, Nahanga
name: Lategan, Francois
Publisher: name: Unknown
Year: 2020
Subjects: subject: Agricultural and Food Policy
subject: Research Methods/ Statistical Methods
subject: agri-food
subject: comparative advantage
subject: competitiveness
subject: TBI
subject: Lafay index

description: This paper uses ‘products mapping’ tool based on the trade balance index (TBI) and Lafay index to investigate trade performance and competitiveness in food items between South Africa (SA) and the EU28 and Africa. The data for this analysis is obtained from the UNCTAD database. SA’s agri-food trade balance climbed from $1.5 billion in 2005 to $3.1 billion in 2017. The results support the conclusion that in bilateral trade, certain products have comparative advantages in relation to African markets despite comparative disadvantages in relation to the EU28 market. Also, there is no or decreasing diversification towards more and new leading products despite the increased intra-regional openness. Leading products (especially fruit and nuts) are the dominant export generating segments in the product’s structure of SA’s agri-food trade. Also, leading products mostly contribute to the positive balance of SA’s agri-food trade. The findings of this study may contribute to business strategies, trade policies, and regional and inter-regional integration.
Additional file 2 of Dietary L-citrulline supplementation modulates nitric oxide synthesis and anti-oxidant status of laying hens during summer season
Creators: name: Uyanga, Victoria A.
name: Jiao, Hongchao
name: Zhao, Jingpeng
name: Wang, Xiaojuan
name: Lin, Hai
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Additional file 2: Fig. S2. Effect of different L-supplementation levels on weekly production performance of laying hens. (A) Egg weights (B) Laying rates and (C) Average daily feed intake of laying. Values are means ± SEM. Significantly different mean values are represented as *P < 0.05 (n = 12 birds per replicate).