cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Geometric Flow Description of Minimal Surfaces
Creators: name: Katsinis, Dimitrios
name: Mitsoulas, Ioannis
name: Pastras, Georgios
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We introduce a description of a minimal surface in a space with boundary, as the world-hypersurface that the entangling surface traces. It does so by evolving from the boundary to the interior of the bulk under an appropriate geometric flow, whose parameter is the holographic coordinate. We specify this geometric flow for arbitrary bulk geometry. In the case of pure AdS spaces, we implement a perturbative approach for the solution of the flow equation around the boundary. We systematically study both the form of the perturbative solution as well as its dependence on the boundary conditions. This expansion is sufficient for the determination of all the divergent terms of the holographic entanglement entropy, including the logarithmic universal terms in odd spacetime bulk dimensions, for an arbitrary entangling surface, in terms of the extrinsic geometry of the latter.
description: 39 pages + 10 pages appendix, 6 figures
A comprehensive catalog of dark matter halo models for SPARC galaxies
Creators: name: Li, Pengfei
name: Lelli, Federico
name: McGaugh, Stacy
name: Schombert, James
Publisher: name: arXiv
Year: 2020
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present rotation curve fits to 175 late-type galaxies from the Spitzer Photometry & Accurate Rotation Curves (SPARC) database using seven dark matter (DM) halo profiles: pseudo-isothermal (pISO), Burkert, Navarro-Frenk-White (NFW), Einasto, Di Cintio (2014, DC14), coreNFW, and a new semi-empirical profile named Lucky13. We marginalize over stellar mass-to-light ratio, galaxy distance, disk inclination, halo concentration and halo mass (and an additional shape parameter for Einasto) using a Markov Chain Monte Carlo method. We find that cored halo models such as the DC14 and Burkert profiles generally provide better fits to rotation curves than the cuspy NFW profile. The stellar mass-halo mass relation from abundance matching is recovered by all halo profiles once imposed as a Bayesian prior, whereas the halo mass-concentration relation is not reproduced in detail by any halo model. We provide an extensive set of figures as well as best-fit parameters in machine-readable tables to facilitate model comparison and the exploration of DM halo properties.
description: 11 pages, 6 figures, 1 table. Accepted for publication in ApJS
Exotic Q=-1/3 Quark Signatures at High-Energy Hadron Colliders
Creators: name: Andre, Troy C.
name: Rosner, Jonathan L.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Isosinglet vector-like quarks are predicted by some unified theories of electroweak and strong interactions. We study hadron collider signatures for the production and decay of isosinglet vector-like quarks with charge -1/3. Previous analyses of Run I data from the Fermilab Tevatron are used to set lower limits of 100--200 GeV/c^2 on the mass of such quarks, depending on assumptions about mixing with Standard Model quarks and the mass of the Higgs boson. For future Tevatron data (E_{c.m.} = 1.96 TeV) the corresponding mass range is (100-270, 100-320) GeV/c^2 for (1, 10) fb^{-1}. At the CERN Large Hadron Collider (LHC) (E_{c.m.} = 14 TeV, 100 fb^{-1}), an analysis of flavor-changing neutral-current decay modes should probe an $h$ quark mass range of 100-1100 GeV/c^2.
description: Minor changes to text, converted to Revtex4, 38 pages, 9 figures, to be submitted to Phys. Rev. D
The Luminosity Function of Cluster Galaxies. III
Creators: name: Parolin, I.
name: Molinari, E.
name: Chincarini, G.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We investigated the optical properties of 7 clusters of galaxies observed in three colors over the range of absolute magnitudes -24 < M < -12. Our aim is to estimate the Luminosity Function and the total cluster luminosity of our sample in order to have information about the formation and the evolution of galaxies in clusters. In this paper, we present the main points of our analysis and give the formal parameters obtained by fitting the data using the maximum likelihood algorithm. We find consistency between our results and other works in literature confirming the bimodal nature of the luminosity function of cluster galaxies. More important, we find that the relation L_opt/ L_X versus L_X is color dependent: Low X ray Luminosity clusters have a bluer galaxy population.
description: 22 pages. Accepted for publication on A&A
Structural Complexity and Plasticity of Signaling Regulation at the Melanocortin-4 Receptor
Creators: name: Kleinau, Gunnar
name: Heyder, Nicolas A.
name: Tao, Ya-Xiong
name: Scheerer, Patrick
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: G protein-coupled receptor
subject: melanocortin receptors
subject: melanocortin-4 receptor
subject: signal transduction
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The melanocortin-4 receptor (MC4R) is a class A G protein-coupled receptor (GPCR), essential for regulation of appetite and metabolism. Pathogenic inactivating MC4R mutations are the most frequent cause of monogenic obesity, a growing medical and socioeconomic problem worldwide. The MC4R mediates either ligand-independent or ligand-dependent signaling. Agonists such as α-melanocyte-stimulating hormone (α-MSH) induce anorexigenic effects, in contrast to the endogenous inverse agonist agouti-related peptide (AgRP), which causes orexigenic effects by suppressing high basal signaling activity. Agonist action triggers the binding of different subtypes of G proteins and arrestins, leading to concomitant induction of diverse intracellular signaling cascades. An increasing number of experimental studies have unraveled molecular properties and mechanisms of MC4R signal transduction related to physiological and pathophysiological aspects. In addition, the MC4R crystal structure was recently determined at 2.75 Å resolution in an inactive state bound with a peptide antagonist. Underpinned by structural homology models of MC4R complexes simulating a presumably active-state conformation compared to the structure of the inactive state, we here briefly summarize the current understanding and key players involved in the MC4R switching process between different activity states. Finally, these perspectives highlight the complexity and plasticity in MC4R signaling regulation and identify gaps in our current knowledge.
Perturbative test of single parameter scaling for 1D random media
Creators: name: Schrader, R.
name: Schulz-Baldes, H.
name: Sedrakyan, A.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Mathematical Physics (math-ph)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: Products of random matrices associated to one-dimensional random media satisfy a central limit theorem assuring convergence to a gaussian centered at the Lyapunov exponent. The hypothesis of single parameter scaling states that its variance is equal to the Lyapunov exponent. We settle discussions about its validity for a wide class of models by proving that, away from anomalies, single parameter scaling holds to lowest order perturbation theory in the disorder strength. However, it is generically violated at higher order. This is explicitely exhibited for the Anderson model.
description: minor corrections to previous version, to appear in Annales H. Poincare
Locking and regularisation of chimeras by periodic forcing
Creators: name: Bolotov, Maxim I.
name: Smirnov, Lev A.
name: Osipov, Grigory V.
name: Pikovsky, Arkady
Publisher: name: arXiv
Year: 2019
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We study how a chimera state in a one-dimensional medium of non-locally coupled oscillators responses to a periodic external force. On a macroscopic level, where chimera can be considered as an oscillating object, forcing leads to entrainment of the chimera's frequency inside an Arnold tongue. On a mesoscopic level, where chimera can be viewed as a inhomogeneous, stationary or nonstationary pattern, strong forcing can lead to reguralization of an unstationary chimera. On a microscopic level of the dynamics of individual oscillators, forcing outside of the Arnold tongue leads to a multi-plateu state with nontrivial locking properties.
A two-stage prediction model for heterogeneous effects of many treatment options: application to drugs for Multiple Sclerosis
Creators: name: Chalkou, Konstantina
name: Steyerberg, Ewout
name: Egger, Matthias
name: Manca, Andrea
name: Pellegrini, Fabio
name: Salanti, Georgia
Publisher: name: arXiv
Year: 2020
Subjects: subject: Methodology (stat.ME)
subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: Treatment effects vary across different patients and estimation of this variability is important for clinical decisions. The aim is to develop a model to estimate the benefit of alternative treatment options for individual patients. Hence, we developed a two-stage prediction model for heterogeneous treatment effects, by combining prognosis research and network meta-analysis methods when individual patient data is available. In a first stage, we develop a prognostic model and we predict the baseline risk of the outcome. In the second stage, we use this baseline risk score from the first stage as a single prognostic factor and effect modifier in a network meta-regression model. We apply the approach to a network meta-analysis of three randomized clinical trials comparing the relapse rate in Natalizumab, Glatiramer Acetate and Dimethyl Fumarate including 3590 patients diagnosed with relapsing-remitting multiple sclerosis. We find that the baseline risk score modifies the relative and absolute treatment effects. Several patient characteristics such as age and disability status impact on the baseline risk of relapse, and this in turn moderates the benefit that may be expected for each of the treatments. For high-risk patients, the treatment that minimizes the risk to relapse in two years is Natalizumab, whereas for low-risk patients Dimethyl Fumarate Fumarate might be a better option. Our approach can be easily extended to all outcomes of interest and has the potential to inform a personalised treatment approach.
Presentation of cervical metastases and pathological mandibular fracture due to pulmonal adenocarcinoma: A case report
Creators: name: Steffen, Claudius
name: Doll, Christian
name: Thieme, Nadine
name: Waluga, Richard
name: Beck-Broichsitter, Benedicta
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Cervical metastasis
subject: Pathological mandibular fracture
subject: Mandible reconstruction
subject: Fibula transplant
subject: Case report
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Introduction: Oral metastatic tumors due to malignancies at distant locations are very rare. There are only few cases in the literature reporting about mandible/cervical metastases. Sometimes the oral finding is the manifestation of the disease. Presentation of case: We report on a 50-year-old patient who was diagnosed with a pathological mandibular fracture and cervical lymph node metastases due to an adenocarcinoma of the lung without other peripheral metastases. Following the interdisciplinary tumor board decision, resection and ipsilateral neck dissection including a mandible reconstruction using a microvascular fibula transplant was performed. The patient received an adjuvant chemotherapy with carboplatin/pemetrexed. Discussion: The combination of cervical metastases and a pathological mandibular fracture has not been reported before. Distinction between oligometastatic and polymetastatic disease may be difficult. Bone lesions and a high number of metastases are associated with a negative outcome. In cases of limited oligometastatic diseases, metastasectomy might sometimes be indicated. Due to the absence of other peripheral metastases decision of metastasectomy was made. Conclusion: Due to rare occurrence of cervical metastases special attention should be paid to the incidence of possible metastases of distant malignancies at uncommon regions.
A System Theoretical Perspective to Gradient-Tracking Algorithms for Distributed Quadratic Optimization
Creators: name: Bin, Michelangelo
name: Notarnicola, Ivano
name: Marconi, Lorenzo
name: Notarstefano, Giuseppe
Publisher: name: arXiv
Year: 2019
Subjects: subject: Systems and Control (eess.SY)
subject: Multiagent Systems (cs.MA)
subject: Optimization and Control (math.OC)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: In this paper we consider a recently developed distributed optimization algorithm based on gradient tracking. We propose a system theory framework to analyze its structural properties on a preliminary, quadratic optimization set-up. Specifically, we focus on a scenario in which agents in a static network want to cooperatively minimize the sum of quadratic cost functions. We show that the gradient tracking distributed algorithm for the investigated program can be viewed as a sparse closed-loop linear system in which the dynamic state-feedback controller includes consensus matrices and optimization (stepsize) parameters. The closed-loop system turns out to be not completely reachable and asymptotic stability can be shown restricted to a proper invariant set. Convergence to the global minimum, in turn, can be obtained only by means of a proper initialization. The proposed system interpretation of the distributed algorithm provides also additional insights on other structural properties and possible design choices that are discussed in the last part of the paper as a starting point for future developments.
Evaluation of the ‘ring sign’ and the ‘core sign’ as a magnetic resonance imaging marker of disease activity and progression in clinically isolated syndrome and early multiple sclerosis
Creators: name: Blindenbacher, Nelly
name: Brunner, Eveline
name: Asseyer, Susanna
name: Scheel, Michael
name: Siebert, Nadja
name: Rasche, Ludwig
name: Bellmann-Strobl, Judith
name: Brandt, Alexander
name: Ruprecht, Klemens
name: Meier, Dominik
name: Wuerfel, Jens
name: Paul, Friedemann
name: Sinnecker, Tim
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Multiple sclerosis
subject: clinically isolated syndrome
subject: 3 Tesla MRI
subject: ring sign
subject: susceptibility weighted imaging
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Brain lesions with a hypointense ring or core were described in multiple sclerosis on susceptibility weighted imaging. Objective: The purpose of this study was to study the evolution and prognostic relevance of susceptibility weighted imaging hypointense lesions in clinically isolated syndrome and early multiple sclerosis. Methods: Sixty-six early multiple sclerosis and clinically isolated syndrome patients were followed over a median period of 2.9 years (range 1.6-4.6 years) and underwent 3T magnetic resonance imaging including 3D susceptibility weighted imaging and T2-weighted fluid-attenuated inversion recovery. We assessed the presence of susceptibility weighted imaging hypointense core or ring lesions, and Expanded Disability Status Scale at baseline and follow-up. Results: Of 611 lesions at baseline, 64 (10.5%) had a susceptibility weighted imaging hypointense core, and 28 (4.6%) had a susceptibility weighted imaging hypointense ring. Hypointense ring lesions were larger (p < 0.001) and more T1w hypointense (p = 0.002) than others. During follow-up, hypointense core lesions became susceptibility weighted imaging isointense (52 lesions, 81%); few developed into hypointense ring lesions (two lesions, 3%). Hypointense ring lesions did not shrink on T2-weighted fluid-attenuated inversion recovery images (p = 0.077, trend towards more enlargement compared to others), while hypointense core lesions more often shrunk in comparison to lesions without a hypointense core (p = 0.002). The number of susceptibility weighted imaging hypointense ring lesions at baseline correlated with Expanded Disability Status Scale progression at follow-up (p = 0.021, R = 0.289). Conclusion: In our cohort of patients with clinically isolated syndrome or early multiple sclerosis, susceptibility weighted imaging hypointense ring lesions were only rarely detectable, but did not shrink and were associated with future disability progression.
Concurrent Process up to Homotopy (I)
Creators: name: Gaucher, Philippe
Publisher: name: arXiv
Year: 2003
Subjects: subject: Algebraic Topology (math.AT)
subject: Category Theory (math.CT)
subject: FOS: Mathematics
subject: 55P99, 68Q85

description: Globular CW-complexes and flows are both geometric models of concurrent processes which allow to model in a precise way the notion of dihomotopy. Dihomotopy is an equivalence relation which preserves computer-scientific properties like the presence or not of deadlock. One constructs an embedding from globular CW-complexes to flows and one proves that two globular CW-complexes are dihomotopic if and only if the corresponding flows are dihomotopic. This note is the first one presenting some of the results of math.AT/0201252.
description: English abstract ; French text ; projet de note aux C.R.A.S
Evolution of primordial perturbations and a fluctuating decay rate
Creators: name: Mazumdar, Anupam
name: Postma, Marieke
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a gauge invariant formalism to study the evolution of curvature perturbations during decay of the inflaton or some other field that dominates the energy density. We specialize to the case where the total curvature perturbation arises predominantly from a spatially fluctuating decay rate. Gaussian fluctuations in the decay rate are present if the inflaton coupling or mass depends on some light field, which freely fluctuates during inflation. The isocurvature fluctuations of the light field seeds the total curvature perturbations, whose amplitude freezes after inflaton decay. We also analyze the resulting curvature perturbation starting with non-negligible values of the initial inflaton curvature. Lastly, we study the effects of the energy density stored in the light field.
description: 14 pages, 2 figures, discussion added, version to be published in Phys. Lett. B
A Moving Frame Algorithm for High Mach Number Hydrodynamics
Creators: name: Trac, Hy
name: Pen, Ue-Li
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a new approach to Eulerian computational fluid dynamics that is designed to work at high Mach numbers encountered in astrophysical hydrodynamic simulations. The Eulerian fluid conservation equations are solved in an adaptive frame moving with the fluid where Mach numbers are minimized. The moving frame approach uses a velocity decomposition technique to define local kinetic variables while storing the bulk kinetic components in a smoothed background velocity field that is associated with the grid velocity. Gravitationally induced accelerations are added to the grid, thereby minimizing the spurious heating problem encountered in cold gas flows. Separately tracking local and bulk flow components allows thermodynamic variables to be accurately calculated in both subsonic and supersonic regions. A main feature of the algorithm, that is not possible in previous Eulerian implementations, is the ability to resolve shocks and prevent spurious heating where both the preshock and postshock Mach numbers are high. The hybrid algorithm combines the high resolution shock capturing ability of the second-order accurate Eulerian TVD scheme with a low-diffusion Lagrangian advection scheme. We have implemented a cosmological code where the hydrodynamic evolution of the baryons is captured using the moving frame algorithm while the gravitational evolution of the collisionless dark matter is tracked using a particle-mesh N-body algorithm. The MACH code is highly suited for simulating the evolution of the IGM where accurate thermodynamic evolution is needed for studies of the Lyman alpha forest, the Sunyaev-Zeldovich effect, and the X-ray background. Hydrodynamic and cosmological tests are described and results presented. The current code is fast, memory-friendly, and parallelized for shared-memory machines.
description: 19 pages, 5 figures
Tomosvaryella subsylvatica Kazerani, Khaghaninia & Kehlmaier 2017
Creators: name: Motamedinia, Behnam
name: Skevington, Jeffrey H.
name: Kelso, Scott
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Pipunculidae
Tomosvaryella
Tomosvaryella subsylvatica

description: Tomosvaryella subsylvatica Kazerani, Khaghaninia & Kehlmaier, 2017
Fig. 62
 Diagnosis: Following Kazerani et al. (2017), this species can be recognized by the elongated surstyli in dorsal view, broadened in basal fourth, narrowed moderately apically; epandrium longer than wide; phallus with three ejaculatory ducts without projection (Kazerani et al. 2017: fig. 3A–D). Based on the shape of phallus in lateral view and surstyli in dorsal view, this species resembles T. sylvatica. It differs by the shape of surstyli in lateral view, being pointed apically; the hind trochanter with three small spines; the r-m cross-vein reaching cell dm before its middle.
 Distribution: Iran (Kazerani et al. 2017; Skevington 2020) (Fig. 62).
description: Published as part of Motamedinia, Behnam, Skevington, Jeffrey H. & Kelso, Scott, 2021, Revision of Tomosvaryella Aczél (Diptera: Pipunculidae) in the Middle East, with description of 19 new species, pp. 1-103 in Zootaxa 5002 (1) on pages 68-69, DOI: 10.11646/zootaxa.5002.1.1, http://zenodo.org/record/5122655
Bioinformatic Identification of Neuroblastoma Microenvironment-Associated Biomarkers with Prognostic Value
Creators: name: Wang, Yi
name: Luo, Huan
name: Cao, Jing
name: Ma, Chao
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Neuroblastoma Mircoenvironment
subject: Cancer
subject: Prognostic Genes
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The microenvironment plays a vital role in the tumor recurrence of neuroblastoma. This research aimed at exploring prognostic genes that are involved in neuroblastoma microenvironment. We used "estimate" R package to calculate the immune/stromal/ESTIMATE scores of each sample of ArrayExpress dataset E-MTAB-8248 based on the ESTIMATE algorithm. Then we found that immune/stromal/ESTIMATE scores were not correlated with age/chromosome 11q, but tumor stage, MYCN gene amplifications, and chromosome 1p. Samples were then divided into high- and low-score groups, and 280 common differentially expressed genes (DEGs) were identified. 64 potential prognostic genes were harvested through overall survival analysis from the common DEGs. 14 prognostic genes (ABCA6, SEPP1, SLAMF8, GPR171, ABCA9, ARHGAP15, IL7R, HLA-DPB1, GZMA, GPR183, CCL19, ITK, FGL2, and CD1C) were obtained after screening in two independent cohorts. GO and KEGG analysis discovered that common DEGs and 64 potential prognostic genes are mainly involved in T-cell activation, lymphocyte activation regulation, leukocyte migration, and the interaction of cytokines and cytokine receptors. Correlation analysis showed that all prognostic genes were negatively correlated with MYCN amplification. Cox analysis identified 5 independent prognostic genes (ARHGAP15, ABCA9, CCL19, SLAMF8, and CD1C).
Correlation between Intraprostatic PSMA Uptake and MRI PI-RADS of [68Ga]Ga-PSMA-11 PET/MRI in Patients with Prostate Cancer: Comparison of PI-RADS Version 2.0 and PI-RADS Version 2.1
Creators: name: Zhao, Jing
name: Mangarova, Dilyana B.
name: Brangsch, Julia
name: Kader, Avan
name: Hamm, Bernd
name: Brenner, Winfried
name: Makowski, Marcus R.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: prostate cancer
subject: multiparametric MRI
subject: PSMA
subject: [68Ga]Ga-PSMA-11 PET/MRI
subject: SUVmax
subject: PSA
subject: molecular imaging
subject: PI-RADS 2.1
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Purpose: We aimed to evaluate the correlation between PSMA uptake and magnetic resonance imaging (MRI) PI-RADS of simultaneous [68Ga]Ga-PSMA-11 PET/MRI regarding PI-RADS version 2.0 and 2.1 respectively and compared the difference between these two versions. Materials and methods: We retrospectively analyzed a total of forty-six patients with biopsy-proven prostate cancer who underwent simultaneous [68Ga]Ga-PSMA-11 PET/MRI. We classified the lesions regarding PI-RADS version 2.0 and 2.1, peripheral zone (PZ), and transitional zone (TZ), respectively. Based on regions of interest (ROI), standardized uptake values maximum (SUVmax), and corresponding lesion-to-background ratios (LBR) of SUVmax of each category, PI-RADS score 1 to 5, were measured. A comparison between PI-RADS version 2.0 and PI-RADS version 2.1 was performed. Results: A total of 215 focal prostate lesions were analyzed, including two subgroups, 125 TZ and 90 PZ. Data are reported as median and interquartile range (IQR). Regarding PI-RADS version 2.1, TZ SUVmax of each category were 1.5 (0.5, 1.9), 1.9 (0.8, 2.3), 3.3 (2.1, 4.6), 4.2 (3.1, 5.7), 7.3 (5.2, 9.7). PZ SUVmax of each category were 1.0 (0.8, 1.6), 2.5 (1.5, 3.2), 3.3 (1.9, 4.5), 4.3 (3.0, 5.4), 7.4 (5.0, 9.3). Regarding the inter-reader agreement of the overall PI-RADS assessment category, the kappa value was 0.723 for version 2.0 and 0.853 for version 2.1. Conclusion: Revisions of PI-RADS version 2.1 results in variations in lesions classification. Lesions with the PI-RADS category of 3, 4, and 5 present relatively higher intraprostatic PSMA uptake, while lesions with the PI-RADS category of 1 and 2 present relatively lower and similar uptake. Version 2.1 has higher inter-reader reproducibility than version 2.0.
Lifshitz tails for the 1D Bernoulli-Anderson model
Creators: name: Schulz-Baldes, Hermann
Publisher: name: arXiv
Year: 2004
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: By using the adequate modified Prüfer variables, precise upper and lower bounds on the density of states in the (internal) Lifshitz tails are proven for a 1D Anderson model with bounded potential.
Appendix A. Resource availability in a seasonally varying enviironment; Appendix B. Temperature responses of species' traits; Appendix C. Invasibility in a seasonal environment; and Appendix D. Temperature and trait response parameters from Latitudinal directionality in ectotherm invasion success
Creators: name: Priyanga Amarasekare
name: Simon, Margaret W.
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: A striking pattern, seen in both fossil and extant taxa, is that tropical ectotherms are better at invading temperate habitats than vice versa. This is puzzling because tropical ectotherms, being thermal specialists, face a harsher abiotic environment and competition from temperate residents that are thermal generalists. We develop a mathematical framework to address this puzzle. We find that (i) tropical ectotherms can invade temperate habitats if they have higher consumption rates and lower mortality during warmer summers, (ii) stronger seasonal fluctuations at higher latitudes create more temporal niches, allowing coexistence of tropical invaders and temperate residents, and (iii) temperate ectotherms’ failure to invade tropical habitats is due to greater mortality rather than lower competitive ability. Our framework yields predictions about population-level outcomes of invasion success based solely on species’ trait responses to temperature. It provides a potential ecological explanation for why the tropics constitute both a cradle and a museum of biodiversity.
Se Status Prediction by Food Intake as Compared to Circulating Biomarkers in a West Algerian Population
Creators: name: Belhadj, Moussa
name: Kazi Tani, Latifa Sarra
name: Dennouni Medjati, Nouria
name: Harek, Yahia
name: Dali Sahi, Majda
name: Sun, Qian
name: Heller, Raban
name: Behar, Ammaria
name: Charlet, Laurent
name: Schomburg, Lutz
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: selenium
subject: monitoring
subject: food intake
subject: predictive model
subject: selenoprotein P
subject: glutathione peroxidase 3
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Algeria is the largest country in Africa, located close to the Mediterranean coastal area, where nutrients consumption varies widely. Local data on selenium composition of foods are not available. We postulated a close correlation between selenium status predictions from food consumption analysis with a quantitative analysis of circulating biomarkers of selenium status. Population characteristics were recorded from 158 participants and dietary selenium intake was calculated by 24-h recall. The average total plasma selenium was 92.4 ± 18.5 µg/L and the mean of selenium intake was 62.7 µg/day. The selenoprotein P concentration was 5.5 ± 2.0 mg/L and glutathione peroxidase 3 activity was 247.3 ± 41.5 U/L. A direct comparison of the dietary-derived selenium status to the circulating selenium biomarkers showed no significant interrelation. Based on absolute intakes of meat, potato and eggs, a model was deduced that outperforms the intake composition-based prediction from all food components significantly (DeLong's test, p = 0.029), yielding an area under the curve of 82%. Selenium status prediction from food intake remains a challenge. Imprecision of survey method or information on nutrient composition makes extrapolating selenium intake from food data providing incorrect insights into the nutritional status of a given population, and laboratory analyses are needed for reliable information.
Complications after CD19+ CAR T-Cell Therapy
Creators: name: Penack, Olaf
name: Koenecke, Christian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: chimeric antigen receptor
subject: CAR T-cells
subject: toxicity
subject: complications
subject: cytokine release syndrome
subject: CD19
subject: lymphoma
subject: leukemia
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Clinical trials demonstrated that CD19+ chimeric antigen receptor (CAR) T-cells can be highly effective against a number of malignancies. However, the complete risk profile of CAR T-cells could not be defined in the initial trials. Currently, there is emerging evidence derived from post approval studies in CD19+ CAR T-cells demonstrating both short-term and medium-term effects, which were unknown at the time of regulatory approval. Here, we review the incidence and the current management of CD19+ CAR T-cell complications. We highlight frequently occurring events, such as cytokine release syndrome, immune effector cell-associated neurotoxicity syndrome, cardiotoxicity, pulmonary toxicity, metabolic complications, secondary macrophage-activation syndrome, and prolonged cytopenia. Furthermore, we present evidence supporting the hypothesis that CAR T-cell-mediated toxicities can involve any other organ system and we discuss the potential risk of long-term complications. Finally, we discuss recent pre-clinical and clinical data shedding new light on the pathophysiology of CAR T-cell-related complications.
Concurrent Process up to Homotopy (II)
Creators: name: Gaucher, Philippe
Publisher: name: arXiv
Year: 2003
Subjects: subject: Algebraic Topology (math.AT)
subject: Category Theory (math.CT)
subject: FOS: Mathematics
subject: 55P99, 68Q85

description: One proves that the category of globular CW-complexes up to dihomotopy is equivalent to the category of flows up to weak dihomotopy. This theorem generalizes the classical theorem which states that the category of CW-complexes up to homotopy is equivalent to the category of topological spaces up to weak homotopy. This note is the second one presenting some of the results of math.AT/0201252.
description: English abstract ; French text ; projet de note aux C.R.A.S
Statistical mechanics of local force dipole responses in computer glasses
Creators: name: Rainone, Corrado
name: Bouchbinder, Eran
name: Lerner, Edan
Publisher: name: arXiv
Year: 2020
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Soft quasilocalized modes (QLMs) are universally featured by structural glasses quenched from a melt, and are supposedly involved in a number of glassy anomalies such as the low temperature scaling of their thermal conductivity and specific heat, and sound attenuation at intermediate frequencies. In computer glasses, QLMs may assume the form of harmonic vibrational modes under a narrow set of circumstances, however direct access to their full distribution over frequency is hindered by hybridizations of QLMs with other low-frequency modes (e.g.~phonons). Previous studies to overcome this issue have demonstrated that the response of a glass to local force dipoles serves as a good proxy for its QLMs; we therefore study here the statistical-mechanical properties of the responses to local force dipoles in computer glasses, over a large range of glass stabilities and in various spatial dimensions, with the goal of revealing properties of the yet-inaccessible full distribution of QLMs' frequencies. We find that, as opposed to the spatial-dimension-independent universal distribution of QLMs' frequencies $ω$ (and, consequently, also of their stiffness $κ\!=\!ω^2$), the distribution of stiffnesses associated with responses to local force dipoles features a (weak) dependence on spatial dimension. We rationalize this dependence by introducing a lattice model that incorporates both the real-space profiles of QLMs --- associated with dimension-dependent long-range elastic fields --- and the universal statistical properties of their frequencies. Finally, we discuss possible connections between our findings and basic aspects of the glass transition problem, and to finite-size effects in plastic activity of ultrastable glasses.
description: 9 pages, 8 figures
On the origin of the X-rays and the nature of accretion in NGC 4261
Creators: name: Gliozzi, M.
name: Sambruna, R. M.
name: Brandt, W. N.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report on the X-ray properties of the radio galaxy NGC 4261, combining information from the XMM, Chandra, and SAX satellites. Goals of this study are to investigate the origin of the X-rays from this low-power radio galaxy and the nature of the accretion process onto the central black hole. The X-ray spectrum of the nuclear source extending up to 100--150 keV is well described by a partially covered (covering factor $>$ 0.8) power law with a photon index \~1.5 absorbed by a column density 5e22 cm^-2. The X-ray luminosity associated with the non-thermal component is ~5e41 erg/s. The nuclear source is embedded in a diffuse hot gas (kT~0.6 keV), whose density profile implies a Bondi accretion rate of 4.5e-2 solar masses/year. For the first time rapid X-ray variability is detected in a low-power radio galaxy at more than 99% confidence level. The observed X-ray spectral and variability properties indicate the accretion flow as the most likely origin of the bulk X-ray continuum.This conclusion is strengthened by energetic considerations based on a comparison between the X-ray luminosity and the kinetic power of the jet, whichalso suggest that the Bondi accretion rate overestimates the actual accretion rate onto the black hole.
description: 12 pages, 6 figures, accepted for publication in A&A
Synthesis, Functionalization and Properties of Uniform Europium-doped Sodium Lanthanum Tungstate and Molybdate (NaLa(XO$_4$)$_2$, X= Mo,W) probes for Luminescent and X-ray Computed Tomography Bioimaging
Creators: name: Laguna, Mariano
name: Nuñez, Nuria O.
name: Becerro, Ana I.
name: Lozano, Gabriel
name: Moros, Maria
name: de la Fuente, Jesús M
name: Corral, Ariadna
name: Balcerzyk, Marcin
name: Ocañaa, Manuel
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applied Physics (physics.app-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: A one-pot simple procedure for the synthesis of uniform, ellipsoidal Eu3+-doped sodium lanthanum tungstate and molybdate (NaLa(XO4)2, X = W, Mo) nanophosphors, functionalized with carboxylate groups, is described. The method is based on a homogeneous precipitation process at 120 C from appropriate Na+, Ln3+ and tungstate or molybdate precursors dissolved in ethylene glycol/water mixtures containing polyacrylic acid. A comparative study of the luminescent properties of both luminescent materials as a function of the Eu3+ doping level has been performed to find the optimum nanophosphor, whose efficiency as X-ray computed tomography contrast agent is also evaluated and compared with that of a commercial probe. Finally, the cell viability and colloidal stability in physiological pH medium of the optimum samples have also been studied to assess their suitability for biomedical applications.
Dynamics of an Unbounded Interface Between Ordered Phases
Creators: name: Krapivsky, P. L.
name: Redner, S.
name: Tailleur, J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We investigate the evolution of a single unbounded interface between ordered phases in two-dimensional Ising ferromagnets that are endowed with single-spin-flip zero-temperature Glauber dynamics. We examine specifically the cases where the interface initially has either one or two corners. In both examples, the interface evolves to a limiting self-similar form. We apply the continuum time-dependent Ginzburg-Landau equation and a microscopic approach to calculate the interface shape. For the single corner system, we also discuss a correspondence between the interface and the Young tableau that represents the partition of the integers.
description: 9 pages, 11 figures, 2-column revtex4 format. V2: references added and discussion section expanded slightly. Final version for PRE. V3: A few small additional editorial changes
Quantization of edge currents for continuous magnetic operators
Creators: name: Kellendonk, Johannes
name: Schulz-Baldes, Hermann
Publisher: name: arXiv
Year: 2004
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: For a magnetic Hamiltonian on a half-plane given as the sum of the Landau operator with Dirichlet boundary conditions and a random potential, a quantization theorem for the edge currents is proven. This shows that the concept of edge channels also makes sense in presence of disorder. Moreover, Gaussian bounds on the heat kernel and its covariant derivatives are obtained.
Exploring the Representation of Depressive Symptoms and the Influence of Stigma in Arabic-Speaking Refugee Outpatients
Creators: name: Lindheimer, Nico
name: Karnouk, Carine
name: Hahn, Eric
name: Churbaji, Dana
name: Schilz, Laura
name: Rayes, Diana
name: Bajbouj, Malek
name: Böge, Kerem
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: refugee
subject: Arabic
subject: depression
subject: somatic
subject: stigma
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The number of distressed refugees from the Arab world is relatively high in Germany and other host countries worldwide. For this specific population, substantial challenges and barriers have already been identified that hamper access to Germany's health care system. This study aims to contribute to this line of research by exploring the representation of depressive symptoms, both somatic and psychological, in order to inform clinicians about the most prevalent symptoms reported by Arabic-speaking refugee outpatients. Furthermore, this paper investigates the longstanding claim that mental health stigma fosters the expression of bodily distress. For these purposes, a total of 100 Arabic-speaking refugee outpatients, mostly Syrians, were recruited in Berlin, Germany. Somatic and psychological symptoms were assessed with the Patient Health Questionnaire (PHQ) 15 and 9, while stigma was assessed with the Brief Version of the Internalized Stigma of Mental Illness Scale (ISMI-10). Study results show that both somatic and psychological symptom severity was moderate while sleeping problems and energy loss were the most reported symptoms across both scales. Stigma was low and showed no association with somatic complaints in a multiple regression analysis, but was associated with more psychological symptoms. A principal factor extraction on the PHQ-15 items revealed five independent, somatic symptom clusters that were interpreted considering the rich poetic resources of the Arabic language. In conclusion, both somatic and psychological symptoms were commonly reported by Arabic-speaking refugees with symptoms of depression. Whereas, stigma does not seem to influence the expression of somatic symptoms, the present results provide first empirical indications for the relationship of symptom expression with the use of explanatory models and conceptualizations of mental illness within the Arabic culture and language. Future research efforts should be dedicated to enhancing our understanding of mental health care needs in this population as well as to exploring other mediators that might help explain the varying degree of somatic symptoms in depression across cultures.
Iranian, Central Asian, and Hellenistic Studies. A Bibliography.
Creators: name: Olbrycht, Marek
Publisher: name: figshare
Year: 2020
Subjects: subject: 210199 Archaeology not elsewhere classified
subject: FOS: History and archaeology
subject: 210103 Archaeology of Asia, Africa and the Americas
subject: 210105 Archaeology of Europe, the Mediterranean and the Levant
subject: 210302 Asian History
subject: 210306 Classical Greek and Roman History
subject: 219999 History and Archaeology not elsewhere classified
subject: History

description: Marek Jan Olbrycht, Iranian, Central Asian, and Hellenistic Studies (until 2020). A Bibliography. Online Resource.
Tomosvaryella pistacia Majnon-Jahromi & Kehlmaier 2017
Creators: name: Motamedinia, Behnam
name: Skevington, Jeffrey H.
name: Kelso, Scott
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Pipunculidae
Tomosvaryella
Tomosvaryella pistacia

description: Tomosvaryella pistacia Majnon-Jahromi & Kehlmaier, 2017
Figs 32A–E, 59
 Diagnosis: This species can be recognized by the shape of surstyli, broadened at base and gradually tapering toward apices in dorsal view (Fig. 32A), both surstyli bent by 90˚ towards abdominal sternite in lateral view (Fig. 32D–E); epandrium small and wider than long in dorsal view (Fig. 32A); phallic guide short, broadened at base; phallus with three ejaculatory ducts, one bearing some small teeth in basal half (Fig. 32D); gonopods and hypandrium symmetrical in ventral view (Fig. 32B). The shape of the surstyli and small epandrium in dorsal view are similar to T. congoana Hardy, 1950 (for illustration see De Meyer, 1993: fig. 10), T. debruyni De Meyer, 1995 (for illustration see De Meyer, 1995: fig. 11) and T. mutata (for illustration see Földvári & De Meyer, 1999: 15 A–D). It differs from T. congoana and T. debruyni by the shape of surstyli in lateral view, which is bent by 90˚ towards the abdominal sternites and differs from T. mutata by the shape of the right surstylus in dorsal view. It is also similar to T. angulata Majnon-Jahromi et al. 2017, as the surstyli of both species are bent by 90˚ towards the abdominal sternite in lateral view and both have a small epandrium in dorsal view. It differs from T. angulata by the lack of distinct and distally-knobbed surstyli in dorsal view (Fig. 32B). Moreover, this species is closely related to T. argyrata and T. argyratoides. See the diagnosis notes under T. argyrata for more details.
 Specimens examined: CYPRUS: Kyrenia, 35°21’N, 33°09’E, 1–8.x.2017, O. Ozden, Malaise trap, JSS52304 (1♂, CNC); ISRAEL: Har Hermon, 33°18’N, 35°46’E, 2000 m a.s.l., 12.vi.1996, A. Freidberg, JSS52095 (1♂, TAU).
 Distribution: Cyprus, Iran, Israel (Skevington 2020) (Fig. 59).
description: Published as part of Motamedinia, Behnam, Skevington, Jeffrey H. & Kelso, Scott, 2021, Revision of Tomosvaryella Aczél (Diptera: Pipunculidae) in the Middle East, with description of 19 new species, pp. 1-103 in Zootaxa 5002 (1) on page 59, DOI: 10.11646/zootaxa.5002.1.1, http://zenodo.org/record/5122655
Two-Mode Squeezed States and Their Superposition in the Motion of Two Trapped Ions
Creators: name: Zeng, Hao-Sheng
name: Kuang, Le-Man
name: Gao, Ke-Lin
Publisher: name: arXiv
Year: 2004
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a method to create two-mode squeezed states and their superposition in the center-of-mass mode and breathing mode of two-trapped ions. Each ion is illuminated simultaneously by two standing waves. One of the fields is tuned to excite resonantly and simultaneously both upper sidebands of the two normal modes, while the other field tuned to the corresponding lower sidebands.
description: 11pages, no figures
Directing random lasing emission using cavity exciton-polaritons
Creators: name: Bouteyre, Paul
name: Nguyen, Hai Son
name: Lauret, Jean-Sébastien
name: Trippé-Allard, Gaëlle
name: Delport, Géraud
name: Lédée, Ferdinand
name: Diab, Hiba
name: Belarouci, Ali
name: Seassal, Christian
name: Garrot, Damien
name: Bretenaker, Fabien
name: Deleporte, Emmanuelle
Publisher: name: arXiv
Year: 2020
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Random lasing is an intriguing phenomenon occurring in disordered structures with optical gain. In such lasers, the scattering of light provides the necessary feedback for lasing action. Because of the light scattering, the random lasing systems emit in all the directions in contrast with the directional emission of the conventional lasers. While this property can be desired in some cases, the control of the emission directionality remains required for most of the applications. Besides, it is well known that the excitation of cavity exciton-polaritons is intrinsically directional. Each wavelength (energy) of the cavity polariton, which is a superposition of an excitonic state and a cavity mode, corresponds to a well-defined propagation direction. We demonstrate in this article that coupling the emission of a 2D random laser with a cavity polaritonic resonance permits to control the direction of emission of the random laser. This results in a directional random lasing whose emission angle with respect to the microcavity axis can be tuned in a large range of angles by varying the cavity detuning. The emission angles reached experimentally in this work are 15.8$^\circ$ and 22.4$^\circ$.
description: Article : 10 pages, 5 figures Supplementary : 11 pages, 14 figures