cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: International management in the framework of multilateral diplomacy
Creators: name: ELS IPR BOOKS
Publisher: name: AlmaU
Year: 2019

description: The study of international management in the framework of multilateral diplomacy enables to define directions of the formation, development and application of competitive advantages of companies in the process of doing business in various countries and using economic, social, demographic, cultural and other characteristics of those countries and interstate interactions. The purpose of publishing the monograph is to summarize the results of scientific and applied research carried out in AlmaU, other scientific institutions or universities and develop constructive recommendations aimed at improving international management on the example of the activities of global trade institutions. This book can be used in practical activities of various TNCs, and as a guide in the learning process of bachelor, master and PhD degree students.
Development, Validation, and Implementation of Cytologically Indeterminate Thyroid Nodule Molecular Testing
Creators: name: Stewardson, Paul
Publisher: name: Cumming School of Medicine
Year: 2024
Subjects: subject: thyroid
subject: cancer
subject: therapy selection
subject: genomics
subject: indeterminate
subject: cytopathology
subject: diagnostics
subject: molecular
subject: oncology
subject: Oncology
subject: Biology--Molecular

description: Introduction: Genetic testing is increasingly used to diagnose or rule out thyroid cancer in indeterminate fine-needle aspirations. The research in this dissertation aimed to locally develop and validate a novel molecular test (ThyroSPEC), explore ancillary risk stratification, and measure the impacts of introducing molecular testing at the population level including for therapy selection. Methods: Comprehensive clinical data were collected prospectively for the first 615 consecutive patients with indeterminate thyroid nodules (ITNs) in a centralized healthcare system following implementation of ThyroSPEC. Accuracy of molecular testing and the impact of the introduction of molecular testing were calculated. A 16-miRNA panel was developed and validated in 127 air-dried smear indeterminate thyroid FNAC specimens and 157 liquid thyroid FNAC specimens. In a separate study on therapy selection, 86 high risk thyroid cancer patients were retrospectively identified and screened for NTRK fusions and RET fusions/mutations with molecular tests including ThyroSPEC. Results: A locally developed, low-cost molecular test achieved an NPV of 76-91% and a PPV of 46-65% in ITNs using only residual biopsy material. Following implementation of molecular testing, diagnostic yield increased 14% (p=0.2442) and repeat FNAs decreased by 24% (p=0.05). A miRNA expression classifier achieved sensitivity of 100% and specificity of 83% in the air-dried smear sample type as an adjunct to ThyroSPEC. However, miRNA expression was indistinguishable between benign and malignant tumors in local liquid cytology specimens. Molecular testing of advanced thyroid cancer patients resulted in the detection of NTRK or RET fusions in up to 40% of systematically defined patient subsets. Conclusion: Introduction of molecular testing offers clinical benefits, even in a low resection rate setting, and directly influences surgical decision-making. ThyroSPEC improved preoperative risk stratification of indeterminate thyroid nodules but requires further stratification for negative test results and intermediate risk mutations. This research also presented a novel miRNA expression classifier that could be used to incrementally risk stratify indeterminate air-dried smear FNAC and suggests that methanol-based preservation of thyroid liquid FNAC may hinder use of miRNA expression levels for molecular diagnostics. Our findings also indicate that ThyroSPEC may be suitable to detect NTRK and RET fusions in advanced thyroid cancers.
Additional file 2. of Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential
Creators: name: Moser, Kara
name: DrÃ¡bek, Elliott
name: Dwivedi, Ankit
name: Stucke, Emily
name: Crabtree, Jonathan
name: Dara, Antoine
name: Shah, Zalak
name: Adams, Matthew
name: Li, Tao
name: Rodrigues, Priscila
name: Koren, Sergey
name: Phillippy, Adam
name: Munro, James
name: Ouattara, Amed
name: Sparklin, Benjamin
name: Dunning Hotopp, Julie
name: Lyke, Kirsten
name: Sadzewicz, Lisa
name: Tallon, Luke
name: Spring, Michele
name: Jongsakul, Krisada
name: Lon, Chanthap
name: Saunders, David
name: Ferreira, Marcelo
name: Nyunt, Myaing
name: Laufer, Miriam
name: Travassos, Mark
name: Sauerwein, Robert
name: Takala-Harrison, Shannon
name: Fraser, Claire
name: Sim, B.
name: Hoffman, Stephen
name: Plowe, Christopher
name: Silva, Joana
Publisher: name: figshare
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplemental Text, Tables, and Figures. Word document containing supplemental information as cited in the main manuscript.
SU(N) magnetism in chains of ultracold alkaline-earth-metal atoms: Mott transitions and quantum correlations
Creators: name: Manmana, Salvatore R.
name: Hazzard, Kaden R. A.
name: Chen, Gang
name: Feiguin, Adrian E.
name: Rey, Ana Maria
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate one dimensional SU$(N)$ Hubbard chains at zero temperature, which can be emulated with ultracold alkaline earth atoms, by using the density matrix renormalization group (DMRG), Bethe ansatz (BA), and bosonization. We compute experimental observables and use the DMRG to benchmark the accuracy of the Bethe ansatz for $N>2$ where the BA is only approximate. In the worst case, we find a relative error $ε\lesssim 4%$ in the BA ground state energy for $N \leq 4$ at filling 1/N, which is due to the fact that BA improperly treats the triply and higher occupied states. Using the DMRG for $N \leq 4$ and the BA for large $N$, we determine the regimes of validity of strong- and weak-coupling perturbation theory for all values of $N$ and in particular, the parameter range in which the system is well described by a SU$(N)$ Heisenberg model at filling 1/N. We find this depends only weakly on $N$. We investigate the Berezinskii-Kosterlitz-Thouless phase transition from a Luttinger liquid to a Mott-insulator by computing the fidelity susceptibility and the Luttinger parameter $K_ρ$ at 1/N filling. The numerical findings give strong evidence that the fidelity susceptibility develops a minimum at a critical interaction strength which is found to occur at a finite positive value for $N>2$.
description: 19 pages, 13 figures and 2 tables; slightly revised version as published in Phys. Rev. A
Scaling limits of recurrent excited random walks on integers
Creators: name: Dolgopyat, Dmitry
name: Kosygina, Elena
Publisher: name: arXiv
Year: 2012
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60K37, 60F17, 60G50

description: We describe scaling limits of recurrent excited random walks (ERWs) on integers in i.i.d. cookie environments with a bounded number of cookies per site. We allow both positive and negative excitations. It is known that ERW is recurrent if and only if the expected total drift per site, delta, belongs to the interval [-1,1]. We show that if |delta|<1 then the diffusively scaled ERW under the averaged measure converges to a (delta,-delta)-perturbed Brownian motion. In the boundary case, |delta|=1, the space scaling has to be adjusted by an extra logarithmic term, and the weak limit of ERW happens to be a constant multiple of the running maximum of the standard Brownian motion, a transient process.
description: 12 pages
LET-1105: National Park Service Acceptance Letter of the Historic American Engineering Record documentation of the Titan I Launch Complex (HAER No. CA-2394) at Vandenberg Space Force Base
Creators: name: McPartland, Mary
Year: 2025
Subjects: subject: Santa Barbara (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3486/santa-barbara-county
subject: Vandenberg Air Force Base (VAFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85469/vandenberg-air-force-base-vafb
subject: Vandenberg Space Force Base (VSFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85584/vandenberg-space-force-base-vsfb
subject: United States of America (Country)
valueUri: https://core.tdar.org/browse/geographic-keyword/384/united-states-of-america-country
subject: North America (Continent)
valueUri: https://core.tdar.org/browse/geographic-keyword/2890/north-america-continent
subject: California (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/1484/california-state-territory
subject: HAER No. CA-2394
valueUri: https://core.tdar.org/browse/other-keyword/173235/haer-no-ca-2394
subject: Titan I Launch Complex
valueUri: https://core.tdar.org/browse/other-keyword/173234/titan-i-launch-complex

description: This document is a letter from the National Park Service's Heritage Documentation Programs acknowledging the receipt and acceptance of the Historic American Engineering Record documentation of the Titan I Launch Complex (HAER No. CA-2394) at Vandenberg Space Force Base.
The muonic longitudinal shower profiles at production
Creators: name: Andringa, S.
name: Cazon, L.
name: Conceição, R.
name: Pimenta, M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: In this paper the longitudinal profile of muon production along the shower axis is studied. The characteristics of this distribution is investigated for different primary masses, zenith angles, primary energies, and different high energy hadronic models. It is found that the shape of this distribution displays universal features similarly to what is known for the electromagnetic profile. The relation between the muon production distribution and the longitudinal electromagnetic evolution is also discussed.
Exploration of Techniques for Working with Sparse Data when Applying Natural Language Processing to Assist a Qualitative Data Analysis of a COVID-19 Open Innovation Community
Creators: name: Yamani, Shirin
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Natural Language Processing
subject: Artificial Intelligence

description: This thesis undertakes a novel integration of Natural Language Processing (NLP) with Qualitative Data Analysis (QDA) to investigate the dynamics of volunteer involvement within the TeamOSV community, a collective formed in response to the COVID-19 pandemic. Central to this study is the exploration of roles and interaction patterns among episodic and habitual volunteers, alongside an analysis of the factors influencing their engagement and disengagement within the community. A significant methodological contribution of this work lies in addressing the sparse data challenge, a common constraint in qualitative research, particularly within multi-class classification contexts. The study employs and critically evaluates a range of NLP techniques, with a focus on data augmentation strategies, to enhance the efficacy of various models, including Logistic Regression, Naive Bayes, Artificial Neural Networks (ANN), Convolutional Neural Networks (CNN), and particularly the Self-Attention model. The proposed framework, identified for its superior performance, demonstrates a noteworthy ability to process and interpret sparse qualitative data, surpassing both traditional approaches in its effectiveness. Furthermore, the thesis explores an in-depth analysis of model variations, assessing the impact of differing configurations of Self-Attention blocks and layers of feed-forward neural networks. It also explores the implications of pre-training on model performance, offering insights into the architectural complexities and training dynamics of NLP models. A crucial aspect of this exploration is the consideration of the trade-offs between model complexity and computational efficiency, highlighting the practical challenges and considerations in deploying these models in qualitative research contexts. Qualitatively, the study offers a detailed examination of volunteer roles within the TeamOSV community. It identifies the distinct contributions and challenges associated with episodic volunteers, characterized by their sporadic engagement patterns, and habitual volunteers, who provide stability and long-termvision. The research also sheds light on the reasons behind volunteer disengagement, such as lifestyle changes and diminishing interest, providing a holistic understanding of volunteer participation in open-source, community-driven projects. The thesis concludes by emphasizing the collaborative strengths of merging NLP with QDA, a union that significantly augments the depth of qualitative research. It proposes a roadmap for future investigations, concentrating on enhancing insights into volunteer coordination within open innovation settings and broadening the application range of NLP in qualitative data examination.
Advancing Temporal and Quality Adaptation in Video Streaming with AV1
Creators: name: Ansari, Mohd Akram
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Adaptive video streaming
subject: DASH
subject: AV1
subject: Temporal adaptive streaming
subject: Video frame interpolation
subject: Computer Science

description: Traditional Adaptive BitRate (ABR) streaming faces the challenge of providing a smooth experience under highly variable network conditions. Many forms of quality adaptation have been proposed, mainly exploring quality or temporal adaptation. The emerging AV1 codec not only advances video encoding and transcoding but also presents opportunities for more flexible quality adaptation. In this thesis, our objective is to push the limit of quality and temporal adaptation with AV1 frame and segment structure. We propose Temporal Adaptive Streaming over QUIC (TASQ) technique and S-frame Adaptive Bitrate (SABR) streaming for temporal and quality adaptation. Our evaluation results show that both TASQ and SABR can significantly improve the smoothness of the streaming playback while conserving bandwidth and improving the Quality- of-Experience (QoE). The only trade-off is short stutters. To smooth out the stutter, we proposed the IFNet-based Frame Filling (IFF) technique. Collectively, TASQ, SABR, and IFF offer a complete quality and temporal adaptation solution.
Means of confusion: how pixel noise affects shear estimates for weak gravitational lensing
Creators: name: Melchior, Peter
name: Viola, Massimo
Publisher: name: arXiv
Year: 2012
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Weak-lensing shear estimates show a troublesome dependence on the apparent brightness of the galaxies used to measure the ellipticity: In several studies, the amplitude of the inferred shear falls sharply with decreasing source significance. This dependence limits the overall ability of upcoming large weak-lensing surveys to constrain cosmological parameters. We seek to provide a concise overview of the impact of pixel noise on weak-lensing measurements, covering the entire path from noisy images to shear estimates. We show that there are at least three distinct layers, where pixel noise not only obscures but biases the outcome of the measurements: 1) the propagation of pixel noise to the non-linear observable ellipticity; 2) the response of the shape-measurement methods to limited amount of information extractable from noisy images; and 3) the reaction of shear estimation statistics to the presence of noise and outliers in the measured ellipticities. We identify and discuss several fundamental problems and show that each of them is able to introduce biases in the range of a few tenths to a few percent for galaxies with typical significance levels. Furthermore, all of these biases do not only depend on the brightness of galaxies but also on their ellipticity, with more elliptical galaxies often being harder to measure correctly. We also discuss existing possibilities to mitigate and novel ideas to avoid the biases induced by pixel noise. We present a new shear estimator that shows a more robust performance for noisy ellipticity samples. Finally, we release the open-source python code to predict and efficiently sample from the noisy ellipticity distribution and the shear estimators used in this work at https://github.com/pmelchior/epsnoise
description: integrated the origin of the moment correlation (thanks to Alan Heavens). source code at https://github.com/pmelchior/epsnoise
Sign of the Casimir-Polder interaction between atoms and oil-water interfaces: Subtle dependence on dielectric properties
Creators: name: Boström, Mathias
name: Ellingsen, Simen Å.
name: Brevik, Iver
name: Parsons, Drew F.
name: Sernelius, Bo E.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We demonstrate that Casimir-Polder energies between noble gas atoms (dissolved in water) and oil-water interfaces are highly surface specific. Both repulsion (e.g. hexane) and attraction (e.g. glycerine and cyclodecane) is found with different oils. For several intermediate oils (e.g. hexadecane, decane, and cyclohexane) both attraction and repulsion can be found in the same system. Near these oil-water interfaces the interaction is repulsive in the non-retarded limit and turns attractive at larger distances as retardation becomes important. These highly surface specific interactions may have a role to play in biological systems where the surface may be more or less accessible to dissolved atoms.
description: 5 pages, 6 figures
Hierarchy of graph matchbox manifolds
Creators: name: Lukina, Olga
Publisher: name: arXiv
Year: 2011
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 57R30 (Primary) 37B05, 54H20 (Secondary)

description: We study a class of graph foliated spaces, or graph matchbox manifolds, initially constructed by Kenyon and Ghys. For graph foliated spaces we introduce a quantifier of dynamical complexity which we call its level. We develop the fusion construction, which allows us to associate to every two graph foliated spaces a third one which contains the former two in its closure. Although the underlying idea of the fusion is simple, it gives us a powerful tool to study graph foliated spaces. Using fusion, we prove that there is a hierarchy of graph foliated spaces at infinite levels. We also construct examples of graph foliated spaces with various dynamical and geometric properties.
description: New examples added at the end of Section 2; Introduction is rewritten. To appear in Topology and its Applications
The location and functional role for the K+-dependent Na+/Ca2+-exchanger, subtype 4 (NCKX4), in mouse brain
Creators: name: Hassan, Mohamed Tarek Ahmed
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: K+-dependent Na+/Ca2+-exchanger
subject: Calcium transport
subject: Choroid plexus epithelial cells
subject: Neurons
subject: Hippocampus
subject: Biochemistry
subject: Neuroscience

description: The K+-dependent Na+/Ca2+ exchanger (NCKX) family has emerged as a major regulator of Ca2+ homeostasis. The family comprises five members (NCKX1-5) that are involved in various neuronal functions. In this thesis, I focus on the fourth member (NCKX4) in the brain. While gene expression analysis and immunoblotting of brain lysates demonstrated high expression of NCKX4 in the brain, the regional distribution of the protein product across the brain is unknown. In Chapter 2, I map the expression of NCKX4 throughout the mouse brain. My data reveal that NCKX4 demonstrates distinct and intense expression in multiple areas involved in crucial functions such as learning and memory, reward processing, movement, and cerebrospinal fluid production. Of interest, NCKX4 expression in the choroid plexus epithelial cells (CPECs) exhibited unexpected intracellular distribution. In Chapter 3, I investigate how NCKX4 contributes to the normal function of CPECs by examining the intracellular structure at which NCKX4 is located and changes induced in Nckx4–/– mice, such as CPEC morphology, CSF composition and secretion, and CPEC subcellular Ca2+ dynamics. My data suggest that NCKX4 is partially localized with markers associated with acidic compartments like endo/lysosomal and secretory vesicles, and loss of NCKX4 may lead to alterations in CSF protein composition. However, no changes in CPEC morphology, CSF ionic concentrations, lateral ventricles volume, or Ca2+ activity were found in Nckx4–/– mice. Finally, based on previous reports that link NCKX4 to Alzheimer’s disease and my data (Chapter 2) that show high expression of NCKX4 in hippocampal mossy fibers, in Chapter 4 I investigate the involvement of NCKX4 in learning and memory through a battery of behavioural experiments. Nckx4–/– mice demonstrate deficits in contextual memory formation and recall as well as less anxiety when placed in an open field. No difference was found in the performance of Nckx4–/– mice in novel object recognition task or Barnes maze compared to wildtype controls. The data presented in this thesis provide an expression map in the brain, with an unexpected subcellular location within CPECs, and reveal undiscovered roles for NCKX4 in neuronal function. Many of these results warrant further investigation.
Phylogeny and systematics of the jumping spider subfamily Euophryinae (Araneae : Salticidae), with consideration of biogeography and genitalic evolution
Creators: name: Zhang, Junxia
Publisher: name: University of British Columbia
Year: 2012

description: The Euophryinae is one of the largest subfamilies of jumping spiders (Salticidae) with worldwide distribution. As the only currently recognized salticid subfamily that has diversified almost evenly in both the Old and New World, its historical biogeography is particularly interesting. To clarify the phylogeny of Euophryinae, I amplified and sequenced four genes (nuclear: 28S rDNA, Actin 5C; mitochondrial: 16S-ND1, COI) from 261 jumping spider species, most euophryines, covering all major distribution areas of this subfamily. The molecular phylogeny strongly supports the monophyly of euophryines. Diolenius and its relatives are shown to be euophryines. The phylogeny also indicates euophryines from different continents tend to form their own clades with few cases of mixture. Temporal divergence of Euophryinae was investigated to understand its historical biogeography. The results suggest rapid radiations early during their evolutionary history, with most divergences after the Eocene. Given the age, several intercontinental dispersal events are required to explain the distribution of euophryines. The suggested tolerance to cold may have facilitated early dispersals between the Old and New World through the Antarctic land bridge. I also extensively studied morphological characteristics of a broad range of euophryine genera and species in order to extend our phylogenetic understanding beyond those taxa sampled for molecular data. Systematics of Euophryinae is discussed and a full list of euophryine genera is provided with 122 genera included (34 genera before this study). Euophryine generic groups and redefined delimitations for some genera are reviewed in detail, with 22 new synonyms of genera and 191 new combinations of species proposed. Photographs and illustrations of 173 euophryine species are provided. In addition, 14 new genera and 96 new species of euophryines are described. Correlated evolution between female copulatory duct and male embolus of euophryines was studied in a phylogenetic context. Intra-specific variation of these traits was also examined. The study reveals a positive correlation between the lengths of female copulatory duct and male embolus among euophryine species. However, the inter- and intra-specific variation patterns are not sufficient to tell whether this correlation results from sexual selection or species recognition mechanisms.
Spin-dependent recombination in Czochralski silicon containing oxide precipitates
Creators: name: Lang, V.
name: Murphy, J. D.
name: Falster, R. J.
name: Morton, J. J. L.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Electrically detected magnetic resonance is used to identify recombination centers in a set of Czochralski grown silicon samples processed to contain strained oxide precipitates with a wide range of densities (~ 1e9 cm-3 to ~ 7e10 cm-3). Measurements reveal that photo-excited charge carriers recombine through Pb0 and Pb1 dangling bonds and comparison to precipitate-free material indicates that these are present at both the sample surface and the oxide precipitates. The electronic recombination rates vary approximately linearly with precipitate density. Additional resonance lines arising from iron-boron and interstitial iron are observed and discussed. Our observations are inconsistent with bolometric heating and interpreted in terms of spin-dependent recombination. Electrically detected magnetic resonance is thus a very powerful and sensitive spectroscopic technique to selectively probe recombination centers in modern photovoltaic device materials.
description: 8 pages, 8 figures
Additional file 2 of Alkaloid profiling and antimicrobial activities of Papaver glaucum and P. decaisnei
Creators: name: Jafaar, Hawraz Jawdat
name: Isbilen, Ovgu
name: Volkan, Ender
name: Sariyar, Gunay
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 2: Table S1. Isolated alkaloids from PG and PD extract.
Effect of feed restriction on muscle fibre characteristics and meat quality traits in pigs
Creators: name: Lebedová, N.
name: Stupka, R.
name: Čítek, J.
name: Okrouhlá, M.
name: Zadinová, K.
Publisher: name: Agronomy Research
Year: 2019
Subjects: fibre types
meat quality
nutrition
pig
article

description: The aim of this study was to evaluate the effect of feed restriction on muscle fibre composition and meat quality traits in pigs. Forty crossbred pigs (Pietrain × Large WhiteSire) × (Landrace × Large WhiteDam) were divided into two feeding groups: ad libitum (AL) and restricted (R1). The effects of feed restriction on muscle fibre characteristics of the musculus longissimus lumborum et thoracis (MLLT) and meat quality traits were evaluated. Muscle fibres were stained and classified as fibre types I, IIA, and IIB. For each muscle fibre type, the fibre density, fibre cross-section area (CSA), and fibre proportion were determined. Fibres IIB were divided into small- (diameter < 46 μm), medium- (diameter 46–86 μm) and large-sized (diameter > 86 μm) fibres. The AL group had significantly lower (P < 0.05) percentage area of IIB fibres and lower (P < 0.01) CSA of IIB fibres than did the R1 group. The R1 group had significantly greater content of large-sized IIB fibres and smaller content of medium-sized IIB fibres than did the AL group (P < 0.05). The group fed ad libitum had greater backfat thickness and smaller lean meat content and tended to have better meat quality traits compared to the restricted group. The results of this study show that strong feed restriction had a negative effect on muscle fibre composition, especially on the amount of large-sized fibres IIB, which are associated with poor meat quality.
(Nichtgelehrte) Gelehrtenkommunikation im Medium des Briefes: Walter Guyers Korrespondenz als Musterfall einer vergangenen Politik?
Creators: name: Hoffmann-Ocon, Andreas
Publisher: name: Zenodo
Year: 2019

description: Während bis in die 1960er und 70er Jahre das Briefgespräch zwischen Hochschullehrern, Gelehrten, aber auch Lehrerbildnern eine Praxis der disziplinären Debatte und Kritik darstellte, gerät aktuell die lange Phase der Briefkorrespondenzen in der Erziehungswissenschaft häufig aus dem Blick. Ein Grund dafür könnte sein, dass aus dem historisch standortgebundenen Verständnis des „digitalen Zeitalters“ heraus, demzufolge das 18. Jahrhundert das Jahrhundert des Briefes gewesen sei (Schmid 2003, S. 113), der Meinungsaustausch von Gelehrten im 20. Jahrhundert im Medium des Briefes als epigonale Sonderform gewertet wird.
description: +repphzhbib2019F
Additional file 3 of Alkaloid profiling and antimicrobial activities of Papaver glaucum and P. decaisnei
Creators: name: Jafaar, Hawraz Jawdat
name: Isbilen, Ovgu
name: Volkan, Ender
name: Sariyar, Gunay
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 3: Table S2. Rf Values of Alkaloids Obtained from P. glaucum (PG) and P. decaisnei (PD) Extracts.
Deriving Conventional Dendritic Cells from ER-Hoxb8 Immortalized Hematopoietic Stem and Progenitor Cells & Evaluating CD36 Dependent Uptake of Oxidized Low-Density Lipoprotein in Type 1 Conventional Dendritic Cells
Creators: name: Moore, Melanie R
Publisher: name: Cumming School of Medicine
Year: 2024
Subjects: subject: Dendritic Cell
subject: Immunology
subject: FOS: Clinical medicine
subject: CD36
subject: Hematopoiesis
subject: Antigen Presentation
subject: Cross Presentation
subject: cDC1
subject: oxLDL
subject: Phagocytosis
subject: Endocytosis
subject: Phagosome Maturation
subject: Apolipoprotein
subject: T Cell
subject: Immunology
subject: Biology--Molecular

description: Dendritic cells (DCs) play a crucial role in immunity, acting as professional antigen presenting cells (APCs) that bridge the innate and adaptive immune systems through antigen presentation. Among DC subtypes, type 1 conventional dendritic cells (cDC1s) excel in cross-presentation, which allows for the loading of processed antigen onto MHC I and is believed to be the primary means by which naïve CD8 T cells are converted into effector CD8 T cells. Despite comprising a small fraction of the total leukocyte population, cDC1s are disproportionately important in tumor environments, where their presence correlates with improved patient survival and treatment response across multiple cancers. However, studying cDCs poses challenges due to limited tools and inefficient methods for obtaining primary murine cDC1s. To address this, we developed a system that consistently provides high yields of cDCs, utilizing an easily accessible cell line of immortalized cDC progenitors. Using fluorescence activated cell sorting (FACS), we enriched an FLT3L-driven Hoxb8-immortalized hematopoietic stem and progenitor (HSPC) cell line to obtain a pre-cDC progenitor population. We then optimized existing methods of obtaining cDCs from bone marrow to consistently obtain cDC populations from our immortalized cDC progenitor cell line. Subsequently, we confirmed that this approach yields cDC subset compositions comparable to those obtained using established primary bone marrow protocols. Additionally, we investigated the role of CD36, a receptor for oxidized low-density lipoprotein (oxLDL), in cDC1s. We demonstrated a significant reduction in oxLDL uptake in cDCs lacking CD36, as well as in cDCs under the influence of macropinocytosis inhibiting drugs, suggesting that CD36-assisted macropinocytosis facilitates oxLDL uptake in cDC1s, ultimately leading to lipid body formation akin to macrophage foam cells. After replicating a commonly observed decrease in cross-presentation abilities in lipid-laden cDC1s, we provided a potential mechanism for this impairment, suggesting that a disruption in the recruitment of apolipoprotein 7c (APOL7C), which is vital to successful cross presentation, may be attributed to a significant oxLDL-dependent delay in phagosomal maturation. In summary, our research sheds light on the interplay between CD36, oxLDL, and cDC1s, offering valuable insights for future cDC studies and providing a promising tool for investigating their roles in immunity and disease.
Classical Limit of the Three-Point Function from Integrability
Creators: name: Kostov, Ivan
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We give analytic expression for the three-point function of three large classical non-BPS operators N=4 Super-Yang-Mills theory at weak coupling. We restrict ourselves to operators belonging to an su(2) sector of the theory. In order to carry out the calculation we derive, by unveiling a hidden factorization property, the thermodynamical limit of Slavnov's determinant.
description: 4 pages, 2 figures
A Genomic and Proteomic Survey of Traits that Modulate Antimicrobial Resistance in Staphylococcus aureus
Creators: name: MacKenzie, Colin Campbell
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Antibiotic resistance is a growing global public health crisis which threatens to remove our primary treatment against bacterial infections. The mechanisms of antibiotic resistance in bacterial pathogens have been extensively studied, however questions surrounding the regulatory mechanisms of these resistance factors in clinical isolates are yet to be answered. In collaboration with the Broad Institute of MIT and Harvard, The Harvard T.H. Chan School of Public Health, and Alberta Precision Laboratories we completed whole-genome sequencing on 7,997 Staphylococcus aureus genomes from a larger study cohort of over 38,000 blood stream infections over a 16-year period. In addition to whole-genome sequencing, the proteomes of the bacterial isolates were quantitatively assessed using Tandem Mass Tag (TMT) ultra-high-performance liquid chromatography mass-spectrometry (UHPLC-MS) methods. Changes in protein levels and growth in the bacterial isolates are related to the variability in the genetic composition of the resistance operons of the specific clinical strains. This study has resulted in the understanding of a complex coregulatory interaction between two resistance operons of Methicillin Resistant S. aureus related to the mecA and blaZ resistance factors. Further, to better understand the metabolic adaptations of pathogens under antibiotic exposure, kinetic flux profiling of Escherichia coli metabolism under various antibiotic stressors was completed through the addition of fully labelled 13C-glucose. This intracellular flux monitoring via UHPLC-MS analysis, at a scale of seconds, has been used to gain insight into the metabolic alterations within E. coli metabolism under the exposure to twelve antibiotics spanning three common classes of antibiotics: DNA synthesis inhibitors, protein synthesis inhibitors, and cell wall synthesis inhibitors. This study has resulted in the classification of important metabolic adaptations occurring because of specific antibiotic compounds. Further, this intracellular metabolic study has shown evidence of a previously unexpected mevalonate pathway in E. coli. These studies have provided insight into the dynamics of pathogen interactions with antibiotics, and a deeper understanding of the antibiotic resistance mechanisms existing in pathogenic strains.
The dynamics of the gravitational two-body problem at fourth post-Newtonian order and at quadratic order in the Newton constant
Creators: name: Foffa, Stefano
name: Sturani, Riccardo
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We derive the conservative part of the Lagrangian and the energy of a gravitationally bound two-body system at fourth post-Newtonian order, up to terms quadratic in the Newton constant. We also show that such terms are compatible with Lorentz invariance and we write an ansatz for the center-of-mass position. The remaining terms carrying higher powers of the Newton constant are currently under investigation.
description: 24 pages, 2 figures. Typos in formulae corrected, references added, more comments in the conclusion in v2
Dipolar ordering of random two-dimensional spin ensemble
Creators: name: Panov, Andrey V.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We theoretically study the randomly positioned two-dimensional system of interacting magnetic dipoles representing the monolayer arrays of single-domain particles. It is showed the onset of the dipolar in-plane superferromagnetic ordering of Ising spins at the surface concentrations of nanoparticles above 0.24. The critical concentration of particles with random easy axis arrangement at zero temperature is 0.65. It is demonstrated that the ensemble with Ising arrangement of spins is ordered at high temperatures close to a particle Curie point.
description: 4 pages, 3 figures
Thermalization of a two-dimensional photon gas in a polymeric host matrix
Creators: name: Schmitt, Julian
name: Damm, Tobias
name: Vewinger, Frank
name: Weitz, Martin
name: Klaers, Jan
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We investigate thermodynamic properties of a two-dimensional photon gas confined by a dye-filled optical microcavity. A thermally equilibrated state of the photon gas is achieved by radiative coupling to a heat bath that is realized with dye molecules embedded in a polymer at room temperature. The chemical potential of the gas is freely adjustable. The optical microcavity consisting of two curved mirrors induces both a non-vanishing effective photon mass and a harmonic trapping potential for the photons. While previous experiments of our group have used liquid dye solutions, the measurements described here are based on dye molecules incorporated into a polymer host matrix. We describe studies of fluorescence properties of dye-doped polymers, and discuss the applicability of Kennard-Stepanov theory in this system. We observe a thermalized two-dimensional photon gas in the solid state based microresonator system. In the future, dye-based solid state systems hold promise for the realization of single-mode light sources in thermal equilibrium based on Bose-Einstein condensation of photons, as well as for solar energy concentrators.
description: 19 pages, 6 figures
Constraints on LVS Compactifications of IIB String Theory
Creators: name: de Alwis, S. P.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We argue that once all theoretical and phenomenological constraints are imposed on the different versions of the Large Volume Scenario (LVS) compactifications of type IIB string theory, one particular version is favored. This is essentially a sequestered one in which the soft terms are generated by Weyl anomaly and RG running effects. We also show that arguments questioning sequestering in LVS models are not relevant in this case.
description: 14 pages, additional discussion of D7 brane case and mSUGRA, reference added
title: Statistical analysis in business and economics. Статистический анализ в бизнесе и экономике
Creators: name: ELS IPR BOOKS
Publisher: name: Балауса, Алматы Менеджмент Университет
Year: 2021

description: Учебное пособие знакомит читателей со статистическими методами, используемыми в бизнесе и экономике. Содержит теоретическую часть, примеры решения типовых задач с применением методики расчета и интерпретации аналитических показателей, задачи для самостоятельной работы, контрольные вопросы, тестовые вопросы для самопроверки и ответы к ним. Для студентов высших учебных заведений.
A Spitzer Space Telescope survey of massive young stellar objects in the G333.2-0.4 giant molecular cloud
Creators: name: Simpson, Janet P.
name: Cotera, Angela S.
name: Burton, Michael G.
name: Cunningham, Maria
name: Lo, Nadia
name: Bains, Indra
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The G333 giant molecular cloud contains a few star clusters and H II regions, plus a number of condensations currently forming stars. We have mapped 13 of these sources with the appearance of young stellar objects (YSOs) with the Spitzer Infrared Spectrograph in the SL, SH, and LH modules (5-36 micron). We use these spectra plus available photometry and images to characterize the YSOs. The spectral energy distributions (SEDs) of all sources peak between 35 and 110 micron, thereby showing their young age. The objects are divided into two groups: YSOs associated with extended emission in IRAC band 2 at 4.5 micron (`outflow sources') and YSOs that have extended emission in all IRAC bands peaking at the longest wavelengths (`red sources'). The two groups of objects have distinctly different spectra: All the YSOs associated with outflows show evidence of massive envelopes surrounding the protostar because the spectra show deep silicate absorption features and absorption by ices at 6.0, 6.8, and 15.2 micron. We identify these YSOs with massive envelopes cool enough to contain ice-coated grains as the `bloated' protostars in the models of Hosokawa et al. All spectral maps show ionized forbidden lines and PAH emission features. For four of the red sources, these lines are concentrated to the centres of the maps, from which we infer that these YSOs are the source of ionizing photons. Both types of objects show evidence of shocks, with most of the outflow sources showing a line of [S I] in the outflows and two of the red sources showing the more highly excited [Ne III] and [S IV] lines in outflow regions at some distance from the YSOs. The 4.5 micron emission seen in the IRAC band 2 images of the outflow sources is not due to H2 lines, which are too faint in the 5-10 micron wavelength region to be as strong as is needed to account for the IRAC band 2 emission.
description: 31 pages and 30 figures in the paper plus 11 figures from the online Supporting Information. To be published in the MNRAS. Version 2 has many small changes (typos, spelling, punctuation) and reordering of the Supporting Information figures to make this version conform to the paper that will be printed in MNRAS
Inradius bounds for stable, minimal surfaces in 3-manifolds with positive scalar curvature
Creators: name: Richardson, James
Publisher: name: University of British Columbia
Year: 2012

description: Concrete topological properties of a manifold can be found by examining its geometry. Theorem 17 of his thesis, due to Myers [Mye41], is one such example of this; it gives an upper bound on the length of any minimizing geodesic in a manifold N in terms of a lower positive bound on the Ricci curvature of N, and concludes that N is compact. Our main result, Theorem 40, is of the same flavour as this, but we are instead concerned with stable, minimal surfaces in manifolds of positive scalar curvature. This result is a version of Proposition 1 in the paper of Schoen and Yau [SY83], written in the context of Riemannian geometry. It states: a stable, minimal 2-submanifold of a 3-manifold whose scalar curvature is bounded below by κ > 0 has a inradius bound of ≤√(8/3) π/√κ, and in particular is compact.
Fischiare, una metafora: lingua e scrittura di un premio letterario.
Creators: name: Idini, Marta
Publisher: name: Gilgameš
Year: 2019

description: Numerous are the comparisons that contemporary literature opens up to styles, genres and words of tradition. The dichotomy that distinguishes the choices of writing between a norm and a misrepresentation of the same has left (now perhaps more openly) the non-place of the linguistic standard emerging as a directional matrix of a more spontaneous communication, which aims to approach the competences - or presumed such - of the reader.

The analysis chooses to investigate the pages of La vita prodigiosa di Isidoro Sifflotin as the winner of the Campiello Opera Prima Award in 2015; what is proposed is therefore a linguistic reasoning that can interrogate the pages of the novel to understand what expedients and narrative mechanisms have led to assign a certain literary validity to a product that, deliberately, does not choose the linguistic literary standard. .
description: Gilgameš, V. 2, N. 2 (2018)
Assessment of wild plants for phytoremediation of heavy metals in soils surrounding the thermal power station
Creators: name: Murtic, S.
name: Jurkovic, J.
name: Basic, E.
name: Hekic, E.
Publisher: name: Agronomy Research
Year: 2019
Subjects: environment
heavy metals
pollution
article

description: The present investigation was carried out to evaluate the phytoextraction potential of three main wild plant species: annual nettle (Urtica urens L.), daisy fleabane (Stenactis annua (L.) Ness.) and yarrow (Achillea millefolium L.) that grow spontaneously in heavy metal contaminated areas near the thermal power station in Kakanj, Bosnia and Herzegovina. Analyses of the heavy metal content (Ni, Fe, Cr, Cu, Zn, Cd, Pb, Mn) in soil and plant samples taken from the examined area were performed using atomic absorption spectrophotometry. The results obtained revealed that the examined soils are polluted by Ni and Pb and contain relatively high value of Cr and Fe. Annual nettle, daisy fleabane and yarrow have not shown high efficiency in the absorption and accumulation of heavy metals from polluted soils, and therefore these plants are not be considered as potential phytoremediators of soils on the examined area. Furthermore, the results of the study undoubtedly confirm the fact that the total content of heavy metals in soils is not a sufficient parameter for estimating the toxicity of heavy metals in soils and consequently for their transfer and accumulation in plants.
Additional file 1 of One out of three bystanders of out-of-hospital cardiac arrests shows signs of pathological psychological processing weeks after the incident - results from structured telephone interviews
Creators: name: Brinkrolf, Peter
name: Metelmann, Bibiana
name: Metelmann, Camilla
name: Baumgarten, Mina
name: Scharte, Carolin
name: Zarbock, Alexander
name: Hahnenkamp, Klaus
name: Bohn, Andreas
Publisher: name: figshare
Year: 2021
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Translation of all answers, grouped into the four categories.