cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
An exome-wide analysis of low frequency and rare variants in relation to risk of breast cancer in African American Women: the AMBER Consortium
Creators: name: Yao, Song
name: Olshan, Andrew F.
name: Liu, Song
name: Ruiz-Narváez, Edward A.
name: Zhu, Qianqian
name: Sucheston-Campbell, Lara E.
name: Palmer, Julie R.
name: Haddad, Stephen A.
name: Lunetta, Kathryn L.
name: Bandera, Elisa V.
name: Bensen, Jeannette T.
name: Haiman, Christopher A.
name: Rosenberg, Lynn
name: Ambrosone, Christine B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: A large percentage of breast cancer heritability remains unaccounted for, and most of the known susceptibility loci have been established in European and Asian populations. Rare variants may contribute to the unexplained heritability of this disease, including in women of African ancestry (AA). We conducted an exome-wide analysis of rare variants in relation to risk of overall and subtype-specific breast cancer in the African American Breast Cancer Epidemiology and Risk (AMBER) Consortium, which includes data from four large studies of AA women. Genotyping on the Illumina Human Exome Beadchip yielded data for 170 812 SNPs and 8287 subjects: 3629 cases (1093 estrogen receptor negative (ER−), 1968 ER+, 568 ER unknown) and 4658 controls, the largest exome chip study to date for AA breast cancer. Pooled gene-based association analyses were performed using the unified optimal sequence kernel association test (SKAT-O) for variants with minor allele frequency (MAF) ≤ 5%. In addition, each variant with MAF >0.5% was tested for association using logistic regression. There were no significant associations with overall breast cancer. However, a novel gene, FBXL22 (P = 8.2×10–6), and a gene previously identified in GWAS of European ancestry populations, PDE4D (P = 1.2×10–6), were significantly associated with ER− breast cancer after correction for multiple testing. Cases with the associated rare variants were also negative for progesterone and human epidermal growth factor receptors—thus, triple-negative cancer. Replication is required to confirm these gene-level associations, which are based on very small counts at extremely rare SNPs.
Chiral symmetry breaking and monopoles
Creators: name: Di Giacomo, Adriano
name: Hasegawa, Masayasu
name: Pucci, Fabrizio
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: To understand the relation between the chiral symmetry breaking and monopoles, the chiral condensate which is the order parameter of the chiral symmetry breaking is calculated in the $\overline{\mbox{MS}}$ scheme at 2 [GeV]. First, we add one pair of monopoles, varying the monopole charges $m_{c}$ from zero to four, to SU(3) quenched configurations by a monopole creation operator. The low-lying eigenvalues of the Overlap Dirac operator are computed from the gauge links of the normal configurations and the configurations with additional monopoles. Next, we compare the distributions of the nearest-neighbor spacing of the low-lying eigenvalues with the prediction of the random matrix theory. The low-lying eigenvalues not depending on the scale parameter $Σ$ are compared to the prediction of the random matrix theory. The results show the consistency with the random matrix theory. Thus, the additional monopoles do not affect the low-lying eigenvalues. Moreover, we discover that the additional monopoles increase the scale parameter $Σ$. We then evaluate the chiral condensate in the $\overline{\mbox{MS}}$ scheme at 2 [GeV] from the scale parameter $Σ$ and the renormalization constant $Z_{S}$. The final results clearly show that the chiral condensate linearly decreases by increasing the monopole charges.
description: A contribution to the 8th International Workshop on Chiral Dynamics, 2015, Pisa, Italy. 8 pages and 5 figures
title: Differentiation of benign and malignant mammary tumours by dynamic MRI using a novel CAD program
Creators: name: Miyazaki, Yoshiaki
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Breast
subject: MR
subject: CAD
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The time intensity curve, or TIC analysis is currently recommended for the benign-malignant differentiation of breast dynamic MR images. [Fig.1] This TIC analysis consists of 2 phases of assessment: In the early phase assessment, the early...
Neuroticism and Interpretive Bias as Risk Factors for Anxiety and Depression
Creators: name: Williams, Alexander
name: Zinbarg, Richard
name: Craske, Michelle
name: Vinograd, Meghan
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: anxiety
subject: depression
subject: interpretation bias
subject: interpretive bias
subject: neuroticism

description: Neuroticism has been associated with mood and anxiety pathology both cross-sectionally and longitudinally. Interpretive bias, or the tendency to interpret ambiguous stimuli in a positive or negative manner, has been associated with mood and anxiety symptomatology, primarily in cross-sectional and bias induction studies. The purpose of the current study was to first examine the role of interpretive bias as a prospective risk factor and second as a possible mediator of the relation between neuroticism and depression and anxiety in a sample of young adults assessed longitudinally. NOTE: Please reach out to the principal investigators of the Youth Emotion Project (Richard Zinbarg, Michelle Craske, Susan Mineka) before using data for any purpose aside from re-running our analyses.
Collaborative Research: GEO OSE TRACK 2: Project Pythia and Pangeo: Building an inclusive geoscience community through accessible, reusable, and reproducible workflows
Creators: name: Rose, Brian E. J.
name: Clyne, John
name: May, Ryan
name: Munroe, James
name: Snyder, Amelia
name: Eroglu, Orhan
name: Tyle, Kevin
Publisher: name: Zenodo
Year: 2023

description: This document contains the full proposal text that the Project Pythia team submitted to the National Science Foundation's Geosciences Open Science Ecosystem (NSF GEO OSE) solicitation, resulting in three linked NSF awards RISE-2324302 (University at Albany), RISE-2324303 (University Corporation for Atmospheric Research), and RISE-2324304 (Code for Science and Society / 2i2c). The document includes the following elements: Public abstract (1 page) Project summary (1 page) Project description (15 pages) References cited (5 pages)
title: Evaluation of image quality on CT images with iterative reconstruction technique in patients with severe intrahepatic lipiodol deposition after transarterial chemoembolisation
Creators: name: Chen, Gao-hong
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: CT
subject: Chemoembolisation
subject: Chemotherapy
subject: Computer Applications-Detection, diagnosis
subject: Embolism / Thrombosis

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Hepatocellular carcinoma (HCC) is an ordinary cause of cancer-related death in China [1,2].Transarterial chemoembolization (TACE) is advocated with clinical benefits in patients with a large tumor burden, which cannot undergo other treatments such...
Genetic variants in the mTOR pathway and breast cancer risk in African American women
Creators: name: Hu, Qiang
name: Palmer, Julie R.
name: Troester, Melissa A.
name: Ambrosone, Christine B.
name: Sucheston-Campbell, Lara
name: Rosenberg, Lynn
name: Cheng, Ting-Yuan David
name: Bensen, Jeannette T.
name: Bandera, Elisa V.
name: Haddad, Stephen
name: Haiman, Christopher A.
name: Lunetta, Kathryn L.
name: Olshan, Andrew F.
name: Yao, Song
name: Ruiz-Narváez, Edward A.
name: Liu, Song
name: Hong, Chi-Chen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The phosphatidylinositol 3-kinase–AKT–mammalian target of rapamycin (mTOR) pathway has been implicated in breast carcinogenesis. However, there has been no large-scale investigation of genetic variants in the mTOR pathway and breast cancer risk. We examined 28847 single-nucleotide polymorphisms (SNPs) in 61 mTOR pathway genes in the African American Breast Cancer Epidemiology and Risk consortium of 3663 cases [1983 estrogen receptor-positive (ER+) and 1098 ER-negative (ER−)] and 4687 controls. Gene-level analyses were conducted using the adaptive rank truncated product (ARTP) test for 10773 SNPs that were not highly correlated (r 2 < 0.8), and SNP-level analyses were conducted with logistic regression. Among genes that were prioritized (nominal P < 0.05, ARTP tests), associations were observed for intronic SNPs TSC2 rs181088346 [odds ratio (OR) of each copy of variant allele = 0.77, 95% confidence interval (CI) = 0.65–0.88 for all breast cancer] and BRAF rs114729114 (OR = 1.53, 95% CI = 1.24–1.91 for all breast cancer and OR = 2.03, 95% CI = 1.50–2.76 for ER− tumors). For ER− tumors, intronic SNPs PGF rs11542848 (OR = 1.38, 95% CI = 1.15–1.66) and rs61759375 (OR = 1.34, 95% CI = 1.14–1.57) and MAPK3 rs78564187 (OR = 1.26, 95% CI = 1.11–1.43) were associated with increased risk. These SNPs were significant at a gene-wide level (Bonferroni-corrected P < 0.05). The variant allele of RPS6KB2 rs35363135, a synonymous coding SNP, was more likely to be observed in ER− than ER+ tumors (OR = 1.18, 95% CI = 1.05–1.31, gene-wide Bonferroni-corrected P = 0.06). In conclusion, specific mTOR pathway genes are potentially important to breast cancer risk and to the ER negativity in African American women.
Double-mode radial-non-radial RR Lyrae stars. OGLE-IV photometry of two high cadence fields in the Galactic bulge
Creators: name: Netzel, H.
name: Smolec, R.
name: Moskalik, P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We analyse the OGLE-IV photometry of the first overtone and double-mode RR Lyrae stars (RRc/RRd) in the two fields towards the Galactic bulge observed with high cadence. In 27 per cent of RRc stars we find additional non-radial mode, with characteristic period ratio, P x /P 1O \in (0.6, 0.64). It strongly corroborates the conclusion arising from the analysis of space photometry of RRc stars, that this form of pulsation must be common. In the Petersen diagram the stars form three sequences. In 20 stars we find two or three close secondary modes simultaneously. The additional modes are clearly non-stationary. Their amplitude and/or phase vary in time. As a result, the patterns observed in the frequency spectra of these stars may be very complex. In some stars the additional modes split into doublets, triplets or appear as a more complex bands of increased power. Subharmonics of additional modes are detected in 20 per cent of stars. They also display a complex structure. Including our previous study of the OGLE-III Galactic bulge data, we have discovered 260 RRc and 2 RRd stars with the additional non-radial mode, which is the largest sample of these stars so far. The additional mode is also detected in two Blazhko RRc stars, which shows that the modulation and additional non-radial mode are not exclusive.
description: 18 pages, 14 figures, accepted for publication in MNRAS
title: Benefits of a weight-bearing MRI in the diagnosis of sub-dislocation and dislocation of the talus bone joint
Creators: name: Giannini, Silvana
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Musculoskeletal joint
subject: MR
subject: Education
subject: Education and training

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: We used a weight bearing MRI to evaluate the actual sub-dislocation of the talus bone joint, after an...
870 micron continuum observations of the bubble-shaped nebula Gum 31
Creators: name: Duronea, N. U.
name: Vasquez, J.
name: Gómez, L.
name: Cappa, C. E.
name: Firpo, V.
name: López-Carballo, C. H.
name: Rubio, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We are presenting here a study of the cold dust in the infrared ring nebula Gum 31. We aim at deriving the physical properties of the molecular gas and dust associated with the nebula, and investigating its correlation with the star formation in the region, that was probably triggered by the expansion of the ionization front. We use 870 micron data obtained with LABOCA to map the dust emission. The obtained LABOCA image was compared to archival IR,radio continuum, and optical images. The 870 micron emission follows the 8 micron (Spitzer), 250 micron, and 500 micron (Herschel) emission distributions showing the classical morphology of a spherical shell. We use the 870 micron and 250 micron images to identify 60 dust clumps in the collected layers of molecular gas using the Gaussclumps algorithm. The clumps have effective deconvolved radii between 0.16 pc and 1.35 pc, masses between 70 Mo and 2800 Mo, and volume densities between 1.1x10^3 cm^-3 and 2.04x10^5 cm^-3. The total mass of the clumps is 37600 Mo. The dust temperature of the clumps is in the range from 21 K to 32 K, while inside the HII region reaches ~ 40 K. The clump mass distribution is well-fitted by a power law dN/dlog(M/Mo) proportional to M^(-alpha), with alpha=0.93+/-0.28. The slope differs from those obtained for the stellar IMF in the solar neighborhood, suggesting that the clumps are not direct progenitors of single stars/protostars. The mass-radius relationship for the 41 clumps detected in the 870 microns emission shows that only 37% of them lie in or above the high-mass star formation threshold, most of them having candidate YSOs projected inside. A comparison of the dynamical age of the HII region with the fragmentation time, allowed us to conclude that the collect and collapse mechanism may be important for the star formation at the edge of Gum 31, although other processes may also be acting.
description: 15 pages, 10 figures. Accepted for publication in A&A
Categorization, Individuation, and the Other-Race Effect
Creators: name: Guilbert, Daniel
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Cognitive Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: This pre-registration is to document our analysis plan for two related experiments exploring how categorization and individuation influence the Other-Race Effect in face recognition. Data collection for this study has been completed, but these data have not been analysed in any way.
Genetic variations in the Hippo signaling pathway and breast cancer risk in African American women in the AMBER Consortium
Creators: name: Zhu, Qianqian
name: Bandera, Elisa V.
name: Olshan, Andrew F.
name: Yao, Song
name: Rosenberg, Lynn
name: Palmer, Julie R.
name: Haiman, Christopher A.
name: Bensen, Jeannette T.
name: Shen, He
name: Hong, Chi-Chen
name: Yang, Nuo
name: Lunetta, Kathryn L.
name: Troester, Melissa A.
name: Liu, Song
name: Hu, Qiang
name: Ruiz-Narvaez, Edward A.
name: Zhang, Jianmin
name: Haddad, Stephen A.
name: Sucheston-Campbell, Lara
name: Ambrosone, Christine B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. Dysfunction of the Hippo pathway components has been linked with breast cancer stem cell regulation, as well as breast tumor progression and metastasis. TAZ, a key component of the Hippo pathway, is highly expressed in triple negative breast cancer; however, the associations of genetic variations in this important pathway with breast cancer risk remain largely unexplored. Here, we analyzed 8309 germline variants in 15 genes from the Hippo pathway with a total of 3663 cases and 4687 controls from the African American Breast Cancer Epidemiology and Risk Consortium. Odds ratios (ORs) were estimated using logistic regression for overall breast cancer, by estrogen receptor (ER) status (1983 ER positive and 1098 ER negative), and for case-only analyses by ER status. The Hippo signaling pathway was significantly associated with ER-negative breast cancer (pathway level P = 0.02). Gene-based analyses revealed that CDH1 was responsible for the pathway association (P < 0.01), with rs4783673 in CDH1 statistically significant after gene-level adjustment for multiple comparisons (P = 9.2×10−5, corrected P = 0.02). rs142697907 in PTPN14 was associated with ER-positive breast cancer and rs2456773 in CDK1 with ER-negativity in case-only analysis after gene-level correction for multiple comparisons (corrected P < 0.05). In conclusion, common genetic variations in the Hippo signaling pathway may contribute to both ER-negative and ER+ breast cancer risk in AA women.
title: Optimisation of DBT using parallel computing aiming to reduce patient dose
Creators: name: Ferreira, Pedro
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Breast
subject: Computer applications
subject: Oncology
subject: Image manipulation / Reconstruction
subject: Mammography
subject: Computer Applications-General
subject: Technical aspects
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: X-ray mammography is the current gold-standard technique for breast cancerdetection [1], however it has some well-known limitations, which prompt the development ofDigital Breast Tomosynthesis (DBT) [2], a 3D radiographic...
title: Relation of visceral adipose tissue to coronary artery calcium in Thai patients
Creators: name: Nimitkul, Kanitha
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Cardiac
subject: CT
subject: Computer Applications-Detection, diagnosis
subject: Arteriosclerosis

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The goal of this study was to determine relationship of abdominal adiposity; body mass index (BMI), waist circumference (WC) and CT measurements of adiposity including visceral fat area (VFA) and subcutaneous fat area (SFA) on the presence of CAC as...
El rol de la familia y la escuela en la socialización política de las actitudes hacia la igualdad de género
Creators: name: Miranda, Daniel
name: Castillo, Juan
name: Iturra, Julio
name: Herrera Leighton, Anais
name: Carrasco, Kevin
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Education
subject: Social and Behavioral Sciences

description: La igualdad de derechos es un principio básico de toda democracia. No sólo como un imperativo ético, sino que también porque se relaciona íntimamente con las posibilidades de desarrollo social y el progreso económico de los países (ONU, 2016; PNUD, 2017) y con la vida democrática, la convivencia y la cohesión social en general (PNUD, 2017). A pesar de esta importancia, las democracias latinoamericanas y caribeñas aún enfrentan grandes desafíos en este ámbito, manteniendo en el tiempo desigualdades sociales, políticas y económicas que afectan principalmente a grupos tradicionalmente desfavorecidos, como las mujeres (Bárcena et al., 2016). En sociedades democráticas la promoción de políticas públicas que se orienten a garantizar la igualdad dependerá, en buena medida, de la existencia de una opinión pública favorable a la promoción y garantía de los derechos de todas las personas. La presente propuesta de investigación pretende aportar a la comprensión de los factores que influyen en el desarrollo de actitudes positivas hacia la igualdad de género en los jóvenes en edad escolar, indagando en el rol que cumplen los dos principales agentes de socialización: la familia y la escuela. En este sentido, se pretende analizar la relación entre las actitudes de los estudiantes hacia la igualdad de género y los recursos socioeconómicos de la familia, las actitudes de sus apoderados hacia la igualdad de género y las características de la escuela a la que asiste el estudiante (más precisamente, la proporción de niñas y la apertura a la discusión en el aula). El objetivo general del estudio es evaluar si dichas características de la escuela mitigan el traspaso intergeneracional de las actitudes hacia la igualdad de género. Para abordar este objetivo se utilizarán los datos de un estudio representativo de los estudiantes de segundo medio que asisten a escuelas de tres regiones chilenas: la Región de Antofagasta, la Región Metropolitana y la Región del Maule. En concreto, los datos del estudio incorporan las respuestas de 1635 estudiantes y 744 apoderados de 64 establecimientos educacionales.
Vitamin D receptor polymorphisms and survival in patients with cutaneous melanoma: a population-based study
Creators: name: Johnson,
name: Busam, Klaus
name: Zanetti, Roberto
name: Taylor,
name: Gallagher, Richard P.
name: Conway,
name: Hao,
name: Paine, Susan
name: Orlow, Irene
name: Gibbs,
name: Gruber, Stephen B.
name: From,
name: Marrett, Loraine D.
name: Kan,
name: Kanetsky, Peter A.
name: Armstrong, Bruce K.
name: Anton-Culver, Hoda
name: Berwick, Marianne
name: Ziogas,
name: Reiner, Anne S.
name: Begg, Colin B.
name: Kricker, Anne
name: Bramson,
name: Groben,
name: Parmar,
name: Madronich,
name: Roy, Pampa
name: Rebbeck,
name: Rosso, Stefano
name: Xu,
name: Tucker,
name: Thomas, Nancy E.
name: Edmiston,
name: Theis,
name: Dwyer, Terence
name: Millikan,
name: Ollila,
name: Frank,
name: Parrish,
name: Sturgeon,
name: Venn,
name: Cust,
name: White,
name: Luo, Li
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Factors known to affect melanoma survival include age at presentation, sex and tumor characteristics. Polymorphisms also appear to modulate survival following diagnosis. Result from other studies suggest that vitamin D receptor (VDR) polymorphisms (SNPs) impact survival in patients with glioma, renal cell carcinoma, lung, breast, prostate and other cancers; however, a comprehensive study of VDR polymorphisms and melanoma-specific survival is lacking. We aimed to investigate whether VDR genetic variation influences survival in patients with cutaneous melanoma. The analysis involved 3566 incident single and multiple primary melanoma cases enrolled in the international population-based Genes, Environment, and Melanoma Study. Melanoma-specific survival outcomes were calculated for each of 38 VDR SNPs using a competing risk analysis after adjustment for covariates. There were 254 (7.1%) deaths due to melanoma during the median 7.6 years follow-up period. VDR SNPs rs7299460, rs3782905, rs2239182, rs12370156, rs2238140, rs7305032, rs1544410 (BsmI) and rs731236 (TaqI) each had a statistically significant (trend P values < 0.05) association with melanoma-specific survival in multivariate analysis. One functional SNP (rs2239182) remained significant after adjustment for multiple testing using the Monte Carlo method. None of the SNPs associated with survival were significantly associated with Breslow thickness, ulceration or mitosis. These results suggest that the VDR gene may influence survival from melanoma, although the mechanism by which VDR exerts its effect does not seem driven by tumor aggressiveness. Further investigations are needed to confirm our results and to understand the relationship between VDR and survival in the combined context of tumor and host characteristics.
A novel 3D-printed brachytherapy applicator and monte Carlo model for the treatment of conjunctival tumors
Creators: name: Matrosic, CK
name: Kronenberg, S
name: Demirci, H
name: Hayman, JA
name: Han, H
name: Lee, C
Publisher: name: Elsevier BV
Year: 2024
Subjects: 3D printing
Conjunctival tumors
Eye plaques
Monte Carlo

description: PURPOSE: To develop a custom low dose rate brachytherapy applicator for the treatment of conjunctival malignancies which leverages 3D-printing technology to provide enhanced design flexibility and availability. METHODS: An elliptical shell applicator inspired by ocular surgery postoperation conformer shells was developed for the placement of the applicator around the cornea of the eye, with a central hole to provide patient comfort. The applicator featured 2 concentric circles of slots for iodine-125 seeds, providing customization of the dose distribution depending on the location of the target. The applicator was modeled using computer-aided design software. The resultant model STL file was used for 3D printing of the applicator and the development of a Monte Carlo model of the applicator and its dose distribution. RESULTS: The applicator was successfully 3D printed using biocompatible resin, which could be sterilized for treatment after manual source loading. A Geant4 model of the applicator was created directly from the STL model and was applied to a phantom to estimate the dose distribution delivered by the applicator. The toroidal dose distribution allowed for treatment of the conjunctiva while reducing dose to the cornea compared to traditional eye plaque designs. CONCLUSIONS: A custom 3D-printed applicator was successfully developed and modeled for the treatment of conjunctival malignancies. This novel applicator design potentially provides higher quality, more customizable dose distributions for patients and the simplicity of the design makes it accessible for any clinic with 3D-printing technology.
Difficulty and help with activities of daily living among older adults living alone during the COVID-19 pandemic: a multi-country population-based study.
Creators: name: Chen, Shanquan
name: Jones, Linda A
name: Jiang, Shan
name: Jin, Huajie
name: Dong, Dong
name: Chen, Xi
name: Wang, Dan
name: Zhang, Yun
name: Xiang, Li
name: Zhu, Anna
name: Cardinal, Rudolf
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Research Article
Activities of daily living
Older adults
Live alone
COVID-19
Domiciliary care

description: BACKGROUND: Older adults who live alone and have difficulties in activities of daily living (ADLs) may have been more vulnerable during the COVID-19 pandemic. However, little is known about pandemic-related changes in ADL assistance (such as home care, domiciliary care) and its international variation. We examined international patterns and changes in provision of ADL assistance, and related these to country-level measures including national income and health service expenditure. METHODS: We analysed data covering 29 countries from three longitudinal cohort studies (Health and Retirement Study, English Longitudinal Study of Aging, and Survey of Health, Ageing and Retirement in Europe). Eligible people were aged ≥50 years and living alone. Outcomes included ADL difficulty status (assessed via six basic ADLs and five instrumental ADLs) and receipt of ADL assistance. Wealth-related inequality and need-related inequity in ADL assistance were measured using Erreygers' corrected concentration index (ECI). Correlations were estimated between prevalence/inequality/inequity in ADL assistance and national health-related indicators. We hypothesized these measures would be associated with health system factors such as affordability and availability of ADL assistance, as well as active ageing awareness. RESULTS: During COVID-19, 18.4% of older adults living alone reported ADL difficulties (ranging from 8.8% in Switzerland to 29.2% in the USA) and 56.8% of those reporting difficulties received ADL assistance (ranging from 38.7% in the UK to 79.8% in Lithuania). Females were more likely to receive ADL assistance than males in 16/29 countries; the sex gap increased further during the pandemic. Wealth-related ECIs indicated socioeconomic equality in ADL assistance within 24/39 countries before the pandemic, and significant favouring of the less wealthy in 18/29 countries during the pandemic. Needs-related ECIs indicated less equity in assistance with ADLs during the pandemic than before. Our hypotheses on the association between ADL provision measures and health system factors were confirmed before COVID-19, but unexpectedly disconfirmed during COVID-19. CONCLUSION: This study revealed an unequal (and in some countries, partly needs-mismatched) response from countries to older adults living alone during the COVID-19 pandemic. The findings might inform future research about, and policies for, older adults living alone, particularly regarding social protection responses during crises.
title: “Fat brook” of posteromedial popliteal fossa: pathologic correlation between cadaver and MR imaging
Creators: name: Song, Yoonah
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Anatomy
subject: Musculoskeletal soft tissue
subject: MR
subject: Experimental investigations

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To describe fluid-like high signal intensity lesion superficial to semimembranosus tendon (“fat brook”) on axial scan of magnetic resonance imaging (MRI) of knee is a problem often encountered in a daily clinical practice. Particularly in...
Temperature Variation in the Dark Cosmic Fluid in the Late Universe
Creators: name: Brevik, Iver
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: A one-component dark energy fluid model of the late universe is considered ($w ζ$. This is just as one would expect physically. The corresponding entropy production is also considered. A special point emphasized in the paper is the analogy that exists between the cosmic fluid and a so-called Maxwell fluid in viscoelasticity.
description: 16 pages latex, no figures, to appear in Mod. Phys. Lett. A. Note: this file was previously posted incorrectly as arXiv:1509.06995v2
Trajectories of perceived superiority across the transition to marriage
Creators: name: Parise, Miriam
name: Donato, Silvia
name: Pagani, Ariela
name: Iafrate, Raffaella
name: Bertoni, Anna
name: Schoebi, Dominik
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: couple relationship
subject: perceived superiority
subject: transition to marriage

description: Perceived superiority, the tendency to regard one’s own relationship as better than other people’s relationships, is a key relationship maintenance mechanism. Little is known about whether and how it changes during the transition to marriage, a pivotal moment in most couples’ life cycle. In a longitudinal project following 97 couples for three waves across the transition, we aim at investigating perceived superiority trajectories.
Location in a Disk City with Consumer Concentration around the Center
Creators: name: Stadler, Manfred
Publisher: name: Universität Tübingen
Year: 2018
Subjects: subject: Economics
subject: 330
subject: disk city
subject: location strategies
subject: concentration of consumer demand

description: The paper studies a two-stage location-price duopoly game in a disk city with consumer concentration around the city center. When consumers are uniformly distributed over the plane, unconstrained firms locate outside of the city. Consumer concentration, however, induces firms to locate nearer to each other and, when the degree of concentration is sufficiently high, inside of the city. Prices and firm profits decrease in the degree of consumer concentration. We explicitly solve the model for classes of cone-shaped, dome-shaped, and bell-shaped consumer densities. In all cases we identify a loss of welfare due to the strategic effect which causes the firms’ spatial differentiation being too large.
title: Dynamic functional connectivity patterns of the subgenual anterior cingulate cortex in patients with refractory and nonrefractory major depressive disorders
Creators: name: Cheng, Bochao
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: CNS
subject: Head and neck
subject: MR
subject: MR-Functional imaging
subject: Neural networks
subject: Imaging sequences

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: fMRI studies have revealed major depressive disorder (MDD) mainly involving deficts in the cortical-limbic circuit. However, few studies reported the differed neuronal circuits between refractory and nonrefractory MDD. And these traditional...
Cataract Phacoemulsification in People with Dementia: Characterization and Outcomes
Creators: name: Grove, Nathan C.
name: Pelak, Victoria S.
name: Christopher, Karen L.
name: Wagner, Brandie D.
name: Lynch, Anne M.
name: Patnaik, Jennifer L.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Developmental Biology
subject: Science Policy
subject: Mental Health

description: To characterize cataract surgery in people with dementia (PWD) using a cataract surgery outcomes database. Demographics, medical and ocular history, surgical characteristics, and postoperative measures were analyzed for differences between PWD and non-PWD cohorts. Patient-level data were analyzed with Fisher’s Exact Test, and eye-level data were analyzed with logistic regression using generalized estimating equations to account for correlation of eyes from the same individual. 507 eyes from 296 PWD were identified using appropriate ICD codes and cross-referenced to a cataract surgery outcomes database containing 12,949 eyes from 7,853 patients who underwent cataract phacoemulsification at a single center between January 2014 and October 2019. PWD were older (p < .001), had shorter duration cataract surgeries (p = .006), and were more likely to have mature cataract (p = .017). The rate of general anesthesia was higher in PWD (p = .005). There were no differences in complication rates between PWD and non-PWD cohorts. Both preoperative best corrected LogMAR distance visual acuity (CDVA) (p < .001) and postoperative CDVA (p < .001) were worse in PWD. CDVA significantly improved in both groups (p < .001); however, the average magnitude of improvement in CDVA was not significantly different between groups (p = .169). PWD present for cataract surgery at a later age and were more likely to have mature cataracts and general anesthesia, but did not have higher rates of complication, and showed significant improvement in CDVA following surgery. These findings should be encouraging to PWD undergoing counseling for cataract surgery, and for the potential for improved function in PWD.
Capacity precommitment, communication, and collusive pricing. Theoretical benchmark and experimental evidence
Creators: name: Güth, Werner
name: Stadler, Manfred
name: Zaby, Alexandra
Publisher: name: Universität Tübingen
Year: 2018
Subjects: subject: Economics
subject: 330
subject: capacity-then-price competition
subject: excessive capacities
subject: cheap talk
subject: intra-play communication
subject: collusion
subject: experimental economics

description: In a capacity-then-price-setting game we experimentally identify capacity precommitment, the possibility to communicate before price choices, and prior competition experience as crucial factors for collusive pricing. The theoretical analysis determines the capacity thresholds above which firms have an incentive to coordinate on higher prices. The experimental data reveals that such intra-play communication after capacity but before price choices has a collusive effect only for capacity levels exceeding these thresholds. Subjects with high capacities generally choose higher prices when they have the possibility to communicate. Asymmetry in capacity choices decreases the truthfulness of price messages as well as the probability to coordinate on the same price.
title: The accuracy of magnetic resonance imaging in diagnosing aseptic loosening of total hip arthroplasty
Creators: name: Derks, Rosalie
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Musculoskeletal joint
subject: MR
subject: Diagnostic procedure

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Totalhip arthroplasty (THP)is a common treatment for patients withsevere osteoarthritis of the hip. Approximately 1.5 million THPare performed each year worldwide. Some types of THP have a 25-years survival rate of 80%. Aseptic loosening is one of...
Brane Brick Models, Toric Calabi-Yau 4-Folds and 2d (0,2) Quivers
Creators: name: Franco, Sebastian
name: Lee, Sangmin
name: Seong, Rak-Kyeong
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Algebraic Geometry (math.AG)
subject: Combinatorics (math.CO)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We introduce brane brick models, a novel type of Type IIA brane configurations consisting of D4-branes ending on an NS5-brane. Brane brick models are T-dual to D1-branes over singular toric Calabi-Yau 4-folds. They fully encode the infinite class of 2d (generically) N=(0,2) gauge theories on the worldvolume of the D1-branes and streamline their connection to the probed geometries. For this purpose, we also introduce new combinatorial procedures for deriving the Calabi-Yau associated to a given gauge theory and vice versa.
description: 80 pages, 53 figures. v3: Minor clarification added. Published version
Reduced mRNA expression of nucleotide excision repair genes in lymphocytes and risk of squamous cell carcinoma of the head and neck
Creators: name: Han, Peng
name: Wei, Qingyi
name: Sturgis, Erich M.
name: Zevallos, Jose P.
name: Liu, Zhensheng
name: Shi, Qiong
name: Lee, Walter
name: Troy, Jesse D.
name: Gao, Fengqin
name: Liu, Hongliang
name: Owzar, Kouros
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Nucleotide excision repair (NER) plays a critical role in the development of smoking-related cancers. We hypothesize that mRNA expression levels of NER genes are associated with risk of the squamous cell carcinoma of head and neck (SCCHN). To test this hypothesis, we conducted a case-control study of 260 SCCHN patients and 246 cancer-free controls by measuring the mRNA expression levels of eight core NER genes in cultured peripheral lymphocytes. Compared with the controls, cases had statistically significantly lower expression levels of DDB1 and ERCC3 (P = 0.015 and 0.041, respectively). Because DDB1 and ERCC3 expression levels were highly correlated, we used DDB1 for further multivariate analyses and modeling. After dividing the subjects by controls' quartiles of expression levels, we found an association between an increased risk of SCCHN and low DDB1 expression levels [adjusted ORs and 95% CIs: 1.92 and 1.11-3.32, 1.48 and 0.85-2.59, 2.00 and 1.15-3.45 for the 2nd-4th quartiles, respectively, compared with the 1st quartile; Ptrend = 0.026]. We also identified a multiplicative interaction between sex and DDB1 expression levels (P = 0.007). Finally, the expanded model with gene expression levels, in addition to demographic and clinical variables, on SCCHN risk was significantly improved, especially among men. In conclusion, reduced DDB1 expression levels were associated with an increased risk of SCCHN. However, these results need to be validated in larger studies.
Ocular Adverse Events After Influenza Vaccination in Older Adults: Self-Controlled Case Series Using a Large Database in Japan
Creators: name: Hashimoto, Yohei
name: Iwagami, Masao
name: Yamana, Hayato
name: Ono, Sachiko
name: Takeuchi, Yoshinori
name: Michihata, Nobuaki
name: Uemura, Kohei
name: Aihara, Makoto
name: Yasunaga, Hideo
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: To clarify the risk of adverse ocular events following influenza vaccination. This self-controlled case series study used a claims database linked to vaccination records of a large city in Japan between April 2014 and September 2021. Individuals aged ≥ 65 years who developed adverse ocular events during the follow-up period were included. The exposure was influenza vaccination. The primary outcome was defined as the occurrence of at least one of the following five eye diseases: uveitis, scleritis, retinal vein occlusion, retinal artery occlusion, or optic neuritis. Conditional Poisson regression was used to estimate the within-subject incidence rate ratio of ocular adverse events during the risk period (0–56 days after vaccination) compared to the control period. A total of 4,527 cases were eligible for the study (median age, 74 years; male, 42%). The incidence rate ratio for the outcome during the risk period was 0.99 (95% confidence interval, 0.87 to 1.14). No increased risk was observed for individual components of the outcome either; the incidence rate ratio was 0.94 (0.78 to 1.13) for uveitis, 1.17 (0.86 to 1.59) for scleritis, 0.98 (0.76 to 1.27) for retinal vein occlusion, 0.89 (0.42 to 1.87) for retinal artery occlusion, and 0.87 (0.44 to 1.70) for optic neuritis. This self-controlled case series showed no apparent increase in the risk of adverse ocular events after influenza vaccination among older adults. These results mitigate the concerns of older adults who may hesitate to receive influenza vaccination for fear of adverse ocular events. HR = hazard ratio; CI = confidence interval; RVO = retinal vein occlusion; SCCS = self-controlled case series
Nafaḥat min balāġat al-Qurʾān: Lamasāt Qurʾānῑya baina mafhūm at-tanāsub wa-āyāt at-tadabbur
نفحات من بلاغة القرآن: لمسات قرآنيّة بين مفهوم التناسب وآيات التدبّر
Ein Hauch von der Rhetorik des Korans: Impulse über das Konzept der Koranharmonie und die Verse der Besinnung
Creators: name: Radhouani, Khaled
Publisher: name: Universität Tübingen
Year: 2018
Subjects: subject: Rhetorik , Koran , Harmonie
subject: 200
subject: 290
subject: 400

description: • رغم تعدّد المؤلّفات عند علماء المسلمين حول علم التناسب القرآني، المعروف في كتبهم بعلم المناسبات فإنّ هذا المبحث ـ على ما أرى ـ مازال مجهولا نسبيّا، خاصّة في المجال العلميّ الغربيّ، وذلك مقارنة بمباحث أخرى تدرس ضمن ما يُعرف بالدراسات الإسلاميّة فيها. لذلك تحاول هذه الدّراسة أن تسهم ـ ولو بشيء يسير ـ في إلقاء بعض الضوء على مفهوم التناسق والانسجام، خاصّة في أبعاده البلاغيّة والسياقيّة والمعنويّة الدلاليّة. ويطرح هذا البحثُ أفكارا مختصرة تتعلّق بمفهوم التاسب ومظاهره بالاعتماد على دراسة أمثلة قرآنيّة مختارة. أمّا المبحث الثاني فيمثّل دراسة لمفهوم التدبّر في القرآن، بالاعتماد على تحليل الآيات الأربع الصريحة المتعلّقة به، تحليلا يرتكز على التناسب.
description: Despite many works written by Muslim scholars concerning the rhetorical, contextual and semantic harmony of the Quran (Arab. tanāsub al-Qurʾān or ʿilm al-munāsabah/munāsabāt), this Quranic discipline - in my opinion – is still relatively unknown and remains little researched, particularly in Western scholarship - compared to other areas of Islamic studies. Hoping to be a little contribution in this regard, this article tries to shed some light on the concept of coherence and interconnectivity within the Quranic verses und Chapters. Based on an analytical and inductive investigation of selected examples, this paper gives some summarized conceptual thoughts on this highly interesting topic. As a practical implementation, the second part tries to deal with four Quranic verses of reflection (Arab. tadabbur) with regard to the rhetoric-semantic and rhetoric-contextual harmony.
description: Trotz zahlreicher Werke muslimischer Gelehrte über die rhetorische, kontextuelle und semantische Harmonie des Korans (arab. tanāsub al-Qurʾān bzw. ʿilm al-munāsabah/munāsabāt), bleibt dieses Koranwissnschaftliche Disziplin – in der westlichen Koranforschung - meines Erachtens und vor allem im Vergleich zu anderen Gebieten der islamischen studien – immer noch relativ wenig erforscht, Mit der Hoffnung, einen kleinen Beitrag in diesem Feld zu leisten, versucht diese Arbeit etwas Licht über das Konzept der Kohärenz und Vereinbarkeit innerhalb der Koransuren und Verse zu werfen. Anhand einer analytischen und induktiven Untersuchung ausgewählter Beispiele werden einige zusammengefasste konzeptionelle Gedanken zu diesem hochinteressanten Thema erläutert. Als praktische Umsetzung, versucht der zweite Teil, auf vier Koranverse der Besinnung (arab. tadabbur) in Hinblick auf die rehtorisch-semantische und rhetorisch-kontextuelle Harmonie des Korans einzugehen.
Association of Smoking Patterns with Vision-Related Disability According to Glaucoma Subtypes
Creators: name: Sencanic, Ivan
name: Dotlic, Jelena
name: Jaksic, Vesna
name: Grgurevic, Anita
name: Gazibara, Tatjana
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: The relationship between smoking and onset of glaucoma has been inconsistent. However, there is a gap in understanding whether tobacco smoking is linked to a worse visual impairment in different glaucoma subtypes. The objective of this study was to examine the association between smoking behavior and vision-related disability in people who have different glaucoma subtypes. A total of 283 people with primary open-angle glaucoma (POAG), primary angle closure glaucoma (PACG), normal tension glaucoma (NTG), and pseudo-exfoliative (PEX) were included in this cross-sectional study. The recruitment of study participants was organized in one of two tertiary centers for eye diseases in Belgrade, Serbia, during their regular eye checks. Information about the duration and quantity of smoking was self-reported. Vision-related impairment was quantified using a validated Glaucoma Quality of Life-15 (GQL-15) questionnaire. A series of multiple linear regression models adjusted for age, gender, severity of glaucoma, lifestyle, and mobility, intraocular pressure level, visual parameters, previous and current therapy, and chronic illnesses suggested that a higher quantity of cigarettes smoked per day was associated with poorer vision-related quality of life only among people with NTG subtypes. This association was absent when smoking duration was tested in the adjusted linear regression model. A higher number of cigarettes smoked daily was associated with poorer vision-related impairment among people who have NTG, but not other glaucoma subtypes. It is recommended that ophthalmologists and other health-care professionals work to improve their patients’ understanding of harmful effects of tobacco smoke and quit smoking.
title: Contribution of magnetic resonance imaging of pelvic floor to de novo stress urinary incontinence post vaginal delivery
Creators: name: Li, Na
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Urinary Tract / Bladder
subject: Obstetrics (Pregnancy / birth / postnatal period)
subject: Pelvis
subject: MR
subject: Outcomes analysis
subject: Pelvic floor dysfunction
subject: Obstetrics

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To evaluate the contributions of levator ani muscle (LAM) injury, vesical neck movement, urethral length and mobility, urethral sphincter dysfunction to stress urinary incontinence (SUI)...