cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identifying parameter regions for multistationarity
Creators: name: Conradi, Carsten
name: Feliu, Elisenda
name: Mincheva, Maya
name: Wiuf, Carsten
Publisher: name: arXiv
Year: 2016
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Algebraic Geometry (math.AG)
subject: Dynamical Systems (math.DS)
subject: FOS: Biological sciences
subject: FOS: Mathematics

description: Mathematical modelling has become an established tool for studying the dynamics of biological systems. Current applications range from building models that reproduce quantitative data to identifying systems with predefined qualitative features, such as switching behaviour, bistability or oscillations. Mathematically, the latter question amounts to identifying parameter values associated with a given qualitative feature. We introduce a procedure to partition the parameter space of a parameterized system of ordinary differential equations into regions for which the system has a unique or multiple equilibria. The procedure is based on the computation of the Brouwer degree, and it creates a multivariate polynomial with parameter depending coefficients. The signs of the coefficients determine parameter regions with and without multistationarity. A particular strength of the procedure is the avoidance of numerical analysis and parameter sampling. The procedure consists of a number of steps. Each of these steps might be addressed algorithmically using various computer programs and available software, or manually. We demonstrate our procedure on several models of gene transcription and cell signalling, and show that in many cases we obtain a complete partitioning of the parameter space with respect to multistationarity.
description: In this version the paper has been substantially rewritten and reorganised. Theorem 1 has been reformulated and Corollary 1 added
Microscopic densities and Fock-Sobolev spaces
Creators: name: Ameur, Yacin
name: Seo, Seong-Mi
Publisher: name: arXiv
Year: 2016
Subjects: subject: Complex Variables (math.CV)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 30H20, 60B20

description: We study two-dimensional eigenvalue ensembles close to certain types of singular points in the bulk of the droplet. We prove existence of a microscopic density which quickly approaches the classical equilibrium density, as the distance from the singularity increases beyond the microscopic scale. As a consequence we obtain asymptotics for the Bergman function of certain Fock-Sobolev spaces of entire functions.
Construction of embedded fMRI resting state functional connectivity networks using manifold learning
Creators: name: Gallos, Ioannis
name: Galaris, Evangelos
name: Siettos, Constantinos
Publisher: name: arXiv
Year: 2020
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: Machine Learning (cs.LG)
subject: Numerical Analysis (math.NA)
subject: FOS: Biological sciences
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: We construct embedded functional connectivity networks (FCN) from benchmark resting-state functional magnetic resonance imaging (rsfMRI) data acquired from patients with schizophrenia and healthy controls based on linear and nonlinear manifold learning algorithms, namely, Multidimensional Scaling (MDS), Isometric Feature Mapping (ISOMAP) and Diffusion Maps. Furthermore, based on key global graph-theoretical properties of the embedded FCN, we compare their classification potential using machine learning techniques. We also assess the performance of two metrics that are widely used for the construction of FCN from fMRI, namely the Euclidean distance and the lagged cross-correlation metric. We show that the FCN constructed with Diffusion Maps and the lagged cross-correlation metric outperform the other combinations.
MPEC 2023-S212 : 2023 SH6
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 SH6

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Proyecto fortalecimiento de los colectivos infantiles y juveniles de comunicaciones como escenarios de formación y transformación social en los barrios Rabolargo, las Margaritas y el Páramo del municipio del Carmen de Bolívar
Creators: name: Lora Muñoz, María E
Publisher: name: Universidad de Cartagena
Year: 2008
Subjects: subject: Trabajo social
subject: Niños - Asistencia social

description: El presente documento es el fruto de las reflexiones y conclusiones elaborado como resultado de la práctica de año social en el colectivo de comunicaciones montes de maría y que fue una apuesta de articulación entre el trabajo social como acción transformadora y participativa con la comunicación social al servicio de lo comunitario. Una alianza, que representa un potencial movilizador de la sociedad a través del uso de los medios masivos de comunicación en procesos ciudadanos como excusa para su desarrollo y que intente plasmar el proyecto fortalecimiento de los colectivos infantiles y juveniles de comunicaciones como escenarios de formación y transformación social en los barrios rabolargo, las margaritas y el páramo del municipio de El Carmen de Bolívar. Así este informe de gestión da cuenta de los planteamientos del proyecto, su desarrollo y principales resultados obtenidos durante su ejecución. De la misma forma presento mis reflexiones y aprendizajes de este año de práctica social, he aquí una invitación a tener en cuenta nuevas herramientas que estimulen la participación, la organización y la gestión comunitaria.
Hierarchical Bayesian Bootstrap for Heterogeneous Treatment Effect Estimation
Creators: name: Oganisian, Arman
name: Mitra, Nandita
name: Roy, Jason
Publisher: name: arXiv
Year: 2020
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: A major focus of causal inference is the estimation of heterogeneous average treatment effects (HTE) - average treatment effects within strata of another variable of interest such as levels of a biomarker, education, or age strata. Inference involves estimating a stratum-specific regression and integrating it over the distribution of confounders in that stratum - which itself must be estimated. Standard practice involves estimating these stratum-specific confounder distributions independently (e.g. via the empirical distribution or Rubin's Bayesian bootstrap), which becomes problematic for sparsely populated strata with few observed confounder vectors. In this paper, we develop a nonparametric hierarchical Bayesian bootstrap (HBB) prior over the stratum-specific confounder distributions for HTE estimation. The HBB partially pools the stratum-specific distributions, thereby allowing principled borrowing of confounder information across strata when sparsity is a concern. We show that posterior inference under the HBB can yield efficiency gains over standard marginalization approaches while avoiding strong parametric assumptions about the confounder distribution. We use our approach to estimate the adverse event risk of proton versus photon chemoradiotherapy across various cancer types.
Conflict Management In Multi-Cultural Project Team (The Case Of China State Construction Engineering Ethiopia, National Stadium Project)
Creators: name: Kiros, Yenework
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2018

description: In order to increase the efficiency of project performance, the improvement of project team performance through avoiding and resolving conflicts is vital. The purpose of this paper is to increase the understanding of how multiculturalism projects will be affected by conflicts. Though conflict exit in every work environment, the nature of projects makes it easier for team members to encounter conflict more than other functional team. And again, the multicultural project team will be suffering more on facing conflicts than the monocultural project team. These case studies were made by selected CSCEC National Stadium Project. According to the data collected and analyzed by this research, many staff of the project are nationals and employed on a temporary basis. These staff are young and degree holders who are supervised by more than one supervisor most of which are Chinese. Respondents replied that the cultural difference between them and supervisors has affected their work both positively and negatively. All the employees replied that they had encountered conflict with their supervisors and mostly compromising conflict resolution technique is used. The causes of conflict mainly lie on task and miscommunication among team members. There were no trainings given to project staffs about multiculturalism. However, employees attempt to understand and respect the cultures of others. The results of the data analyses show that multiculturalism has an effect in project team conflict and conflict management and should be considered while managing such project team in the China State Construction Engineering Corporation, National Stadium Project.
Estudios preliminares para la implementación de métodos de almacenamiento y de conservación de alimentos en buques de altamar
Creators: name: Barrios Quiroz, Gina Paola
name: Echenique Montes, Michael
Publisher: name: Universidad de Cartagena
Year: 2011
Subjects: Conservación de alimentos
Higiene de los alimentos

description: Tesis (Ingeniero de Alimentos).--Universidad de Cartagena. Facultad de Ciencias E Ingenierías. Programa de Ingeniería de Alimentos, 2011
description: En el presente estudio preliminar para la implementación de métodos de almacenamiento y de conservación de alimentos en buques en altamar, se consideraron tres aspectos. El primero de ellos, Identificar las condiciones higiénico-sanitarias mediante la realización de un perfil sanitario de aquellos lugares donde se almacenan y se conservan los alimentos a ser consumidos por la tripulación. El segundo aspecto guarda relación con la identificación de las falencias presentadas en la conservación de aquellos alimentos con pérdida de sabor, olor y valor nutritivo con mayor rapidez en altamar. El tercer aspecto es la realización de un manual de métodos de almacenamiento y conservación de alimentos para que la empresa CABRALES PAFFEN S.A, suministre un mejor servicio, brindando la información necesaria a sus clientes Se realizó una investigación descriptiva de todo el proceso de almacenamiento y conservación que actualmente tienen los barcos, observando la trazabilidad de los productos que CABRALES PAFFEN S.A entrega a SEATECH INTERNATIONAL INC. Los métodos más aplicados en este tipo de embarcaciones son los de bajas temperaturas (refrigeración y congelación), suministrando información detallada de las temperaturas requeridas por cada tipo de alimentos, es decir, perecederos, semi-perecederos y no perecederos evitando la degradación de alimentos por parte de microorganismos, logrando así brindar la documentación necesaria donde estén descritas las tecnologías avanzadas de conservación de alimentos, para que se apliquen en un corto y/o mediano plazo. De esta manera el presente trabajo sirve como fuente para que las empresas dedicadas a proveer o suministrar alimentos a los barcos pesqueros, cuenten con las herramientas necesarias y adecuadas para almacenar y conservar los alimentos en altamar, sitio de sus actividades
General expressions for extra-dimensional tree amplitudes and all-plus 1-loop integrands in Q-cut representaion
Creators: name: An, Yang
name: Li, Yi
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper, we give the general expressions for a special series of tree amplitudes of the Yang-Mills theory. This series of amplitudes have two adjacent massless spin-1 particles with extra-dimensional momenta and any number of positive helicity gluons. With special helicity choices, we use the spinor helicity formalism to express these n-point amplitudes in compact forms, and find a clever way to use the BCFW recursion relations to prove the results. Then these amplitudes are used to form the complete 1-loop all-plus integrand with any number of gluons, expressed in the Q-cut representation.
description: Published version with 20 pages, 8 figure, and 1 new reference
Computing the covering radius of a polytope with an application to lonely runners
Creators: name: Cslovjecsek, Jana
name: Malikiosis, Romanos Diogenes
name: Naszódi, Márton
name: Schymura, Matthias
Publisher: name: arXiv
Year: 2020
Subjects: subject: Combinatorics (math.CO)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: We are concerned with the computational problem of determining the covering radius of a rational polytope. This parameter is defined as the minimal dilation factor that is needed for the lattice translates of the correspondingly dilated polytope to cover the whole space. As our main result, we describe a new algorithm for this problem, which is simpler, more efficient and easier to implement than the only prior algorithm of Kannan (1992). Motivated by a variant of the famous Lonely Runner Conjecture, we use its geometric interpretation in terms of covering radii of zonotopes, and apply our algorithm to prove the first open case of three runners with individual starting points.
description: 22 pages, 4 tables, 2 figures, revised version
Objective trajectories in hybrid classical-quantum dynamics
Creators: name: Oppenheim, Jonathan
name: Sparaciari, Carlo
name: Šoda, Barbara
name: Weller-Davies, Zachary
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Consistent dynamics which couples classical and quantum degrees of freedom exists, provided it is stochastic. This dynamics is linear in the hybrid state, completely positive and trace preserving. One application of this is to study the back-reaction of quantum fields on space-time which does not suffer from the pathologies of the semi-classical equations. Here we introduce several toy models in which to study hybrid classical-quantum evolution, including a qubit coupled to a particle in a potential, and a quantum harmonic oscillator coupled to a classical one. We present an unravelling approach to calculate the dynamics, and provide code to numerically simulate it. Unlike the purely quantum case, the trajectories (or histories) of this unravelling can be unique, conditioned on the classical degrees of freedom for discrete realisations of the dynamics, when different jumps in the classical degrees of freedom are accompanied by the action of unique operators on the quantum system. As a result, the ``measurement postulate'' of quantum theory is not needed; quantum systems become classical because they interact with a fundamentally classical field.
description: 35 pages (Quantum format), 8 figures; appendix 6 pages. Accepted for publication in Quantum
Fuglede's conjecture holds for cyclic groups of order $pqrs$
Creators: name: Kiss, Gergely
name: Malikiosis, Romanos Diogenes
name: Somlai, Gábor
name: Vizer, Máté
Publisher: name: arXiv
Year: 2020
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 43A65, 20F70, 20K01, 13F20, 52C22

description: The tile-spectral direction of the discrete Fuglede-conjecture is well-known for cyclic groups of square-free order, initiated by Laba and Meyerowitz, but the spectral-tile direction is far from being well-understood. The product of at most three primes as the order of the cyclic group was studied intensely in the last couple of years. In this paper we study the case when the order of the cyclic group is the product of four different primes and prove that Fuglede's conjecture holds in this case.
description: 20 pages, 1 figures
Plan de repuesta a los riegos en proyectos de tipo residencial Urbanización el Country II
Creators: name: Pérez Ozuna, Fanny Beatriz
name: Tatis Montes, Diana Carolina
Publisher: name: Universidad de Cartagena
Year: 2015
Subjects: Administración de proyectos
Industria de la construcción

description: Tesis (Ingeniero Civil).--Universidad de Cartagena. Facultad de Ciencias E Ingenierías. Programa de Ingeniería Civil, 2015
description: En la presente investigación se propone el plan de respuesta a los riesgos constructivos que se pueden presentar en proyectos de tipo residencial, escogiendo como caso de estudio el proyecto residencial Urbanización Country II, localizado en el municipio de Turbaco en el departamento de Bolívar. El desarrollo se llevó a cabo de acuerdo con los estándares de administración de proyectos de la Guía del PMBOK® (Guía de los Fundamentos para la Dirección de Proyectos) del Project Management Institute (PMI).
Constrained high-index saddle dynamics for the solution landscape with equality constraints
Creators: name: Yin, Jianyuan
name: Huang, Zhen
name: Zhang, Lei
Publisher: name: arXiv
Year: 2020
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: We propose a constrained high-index saddle dynamics (CHiSD) method to search for index-$k$ saddle points of an energy functional subject to equality constraints. With Riemannian manifold tools, the CHiSD is derived in a minimax framework, and its linear stability at an index-$k$ saddle point is proved. To ensure the manifold property, the CHiSD is numerically implemented using retractions and vector transport. Then we present a numerical approach by combining CHiSD with downward and upward search algorithms to construct the solution landscape in the presence of equality constraints. We apply the Thomson problem and the Bose-Einstein condensation as numerical examples to demonstrate the efficiency of the proposed method.
Assessment of the Performance of 20/80 Condominium Housing Project Offices: The Case of Addis Ababa Bole Sub city "Arabsa" Site
Creators: name: Habtewold, Solomon
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2018

description: This study assesses the performance of the condominium house project offices in Addis Ababa Bole Sub city "Arabsa" sites. Based on the key project participants; clients, consultants, and contractor's responses, the most important factors affecting the project performance were identified using the Relative Importance index (RII). Semi-structured questionnaire was administered to 50 of key players in the implementation process. Furthermore, interviews were used as data collection tools and secondary sources were also used as data sources. The findings indicate that all 3 groups agree that the most important factors affecting project performance are: escalation of material prices, financial problem, lack of planning and scheduling, delay in progress payments, lack of communication and coordination among the project participants, poor decision-making and shortage of qualified personnel. Based on these findings, the paper recommends that: 1) project clients should consider appropriate inflation factor during cost estimation process and advised to setup stores for required materials. Project clients must work collaboratively with contractors and facilitate regular payments in order to overcome delays, disputes and claims; 2) The owners should focus on selection of competent consultants and reliable contractors and also allow to participate competent international contractors to speed up the project. 3) The project managers and other top-level managers should have effective decision-making ability in order to accomplish the projects successfully.
Electron Track Reconstruction and Improved Modulation for Photoelectric X-ray Polarimetry
Creators: name: Li, Tenglin
name: Zeng, Ming
name: Feng, Hua
name: Cang, Jirong
name: Li, Hong
name: Zhang, Heng
name: Zeng, Zhi
name: Cheng, Jianping
name: Ma, Hao
name: Liu, Yinong
Publisher: name: arXiv
Year: 2016
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The key to photoelectric X-ray polarimetry is the determination of the emission direction of photoelectrons. Because of the low mass of an electron, the ionisation trajectory is not straight and the useful information needed for polarimetry is stored mostly in the initial part of the track where less energy is deposited. We present a new algorithm, based on the shortest path problem in graph theory, to reconstruct the 2D electron track from the measured image that is blurred due to transversal diffusion along drift and multiplication in the gas chamber. Compared with previous methods based on moment analysis, this algorithm allows us to identify the photoelectric interaction point more accurately and precisely for complicated tracks resulting from high energy photons or low pressure chambers. This leads to a better position resolution and a higher degree of modulation toward high energy X-rays. The new algorithm is justified using simulations and measurements with the gas pixel detector (GPD), and it should also work for other polarimetric techniques such as a time projection chamber (TPC). As the improvement is restricted in the high energy band, this new algorithm shows limited improvement for the sensitivity of GPD polarimeters, but it may have a larger potential for low-pressure TPC polarimeters.
description: Corrected typos. 15 pages, 10 figures, accepted by NIM A (DOI:10.1016/j.nima.2017.03.050)
Multifunctional branched poly(ester amide)s particles for brain targeting
Creators: name: ZIA, AADARASH
Publisher: name: Monash University
Year: 2021
Subjects: Pharmaceutical sciences
Neurosciences not elsewhere classified
Nanomaterials
Nanomedicine

description: Brain diseases represent complex diseases due to lack of therapy which could be attributed to not fully know mechanisms and the presence of a barrier between blood and the brain that restricts the entry of therapeutic moieties. This thesis focuses on the development of brain-targeted particles which have the ability to cross the blood-brain barrier. It also highlights the development of physiologically relevant brain models and their use to study the behavior of these particles.
Label Enhanced Event Detection with Heterogeneous Graph Attention Networks
Creators: name: Cui, Shiyao
name: Yu, Bowen
name: Cong, Xin
name: Liu, Tingwen
name: Li, Quangang
name: Shi, Jinqiao
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Event Detection (ED) aims to recognize instances of specified types of event triggers in text. Different from English ED, Chinese ED suffers from the problem of word-trigger mismatch due to the uncertain word boundaries. Existing approaches injecting word information into character-level models have achieved promising progress to alleviate this problem, but they are limited by two issues. First, the interaction between characters and lexicon words is not fully exploited. Second, they ignore the semantic information provided by event labels. We thus propose a novel architecture named Label enhanced Heterogeneous Graph Attention Networks (L-HGAT). Specifically, we transform each sentence into a graph, where character nodes and word nodes are connected with different types of edges, so that the interaction between words and characters is fully reserved. A heterogeneous graph attention networks is then introduced to propagate relational message and enrich information interaction. Furthermore, we convert each label into a trigger-prototype-based embedding, and design a margin loss to guide the model distinguish confusing event labels. Experiments on two benchmark datasets show that our model achieves significant improvement over a range of competitive baseline methods.
Online Service Migration in Mobile Edge with Incomplete System Information: A Deep Recurrent Actor-Critic Learning Approach
Creators: name: Wang, Jin
name: Hu, Jia
name: Min, Geyong
name: Ni, Qiang
name: El-Ghazawi, Tarek
Publisher: name: arXiv
Year: 2020
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Multi-access Edge Computing (MEC) is an emerging computing paradigm that extends cloud computing to the network edge to support resource-intensive applications on mobile devices. As a crucial problem in MEC, service migration needs to decide how to migrate user services for maintaining the Quality-of-Service when users roam between MEC servers with limited coverage and capacity. However, finding an optimal migration policy is intractable due to the dynamic MEC environment and user mobility. Many existing studies make centralized migration decisions based on complete system-level information, which is time-consuming and also lacks desirable scalability. To address these challenges, we propose a novel learning-driven method, which is user-centric and can make effective online migration decisions by utilizing incomplete system-level information. Specifically, the service migration problem is modeled as a Partially Observable Markov Decision Process (POMDP). To solve the POMDP, we design a new encoder network that combines a Long Short-Term Memory (LSTM) and an embedding matrix for effective extraction of hidden information, and further propose a tailored off-policy actor-critic algorithm for efficient training. The extensive experimental results based on real-world mobility traces demonstrate that this new method consistently outperforms both the heuristic and state-of-the-art learning-driven algorithms and can achieve near-optimal results on various MEC scenarios.
A functional identity for Mahler measures of non-tempered polynomials
Creators: name: Samart, Detchat
Publisher: name: arXiv
Year: 2020
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11R06, 11F67, 11G05, 33C75, 33E05

description: We establish a functional identity for Mahler measures of the two-parametric family $P_{a,c}(x,y)=a(x+1/x)+y+1/y+c$. Our result extends an identity proven in a paper of Lalín, Zudilin and Samart. As a by-product, we obtain evaluations of $m(P_{a,c})$ for some algebraic values of $a$ and $c$ in terms of special values of $L$-functions and logarithms. We also give a sufficient condition for validity of a certain identity between the elliptic integrals of the first and the third kind, which implies several identities for $m(P_{a,c})$.
description: 11 pages
Disturbance-Based Measure of Macroscopic Coherence
Creators: name: Kwon, Hyukjoon
name: Park, Chae-Yeun
name: Tan, Kok Chuan
name: Jeong, Hyunseok
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a measure of macroscopic coherence based on the degree of disturbance caused by a coarse-grained measurement. Based on our measure, we point out that recently proposed criteria of macroscopic coherence may lead to inconsistent results when considering certain states such as a product of microscopic superpositions. An inequality relation is proved that relates the Wigner-Yanase-Dyson skew information and the measurement disturbance, providing arguments as to why our approach is able to rule out such inconsistencies. We show that our measure can also quantify the fragility of a quantum state to a certain type of decoherence. Our work provides a general framework of quantifying macroscopic coherence from an operational point of view, based on the relationship between the precision of the measurement and disturbance of the quantum state.
description: 17 pages, 3 figures
Aplicación de un modelo in vitro para el análisis molecular de la respuesta inmune temprana a Mycobacterium tuberculosis H37Ra utilizando la tecnología de Microarray de Oligonucleótidos
Creators: name: Bettín Martínez, Alfonso Carlos
Publisher: name: Universidad de Cartagena
Year: 2010
Subjects: subject: Biomoléculas - Análisis
subject: Células B - Tumores
subject: Antígenos
subject: Neoplasmas de las células B

description: La principal defensa del huésped humano a la infección por Mycobacterium tuberculosis es la formación de granulomas, una colección organizada de macrófagos activados, que incluyen células gigantes multinucleadas y epiteloides, rodeadas por linfocitos. Para investigar las bases moleculares de la formación temprana de los granulomas tuberculosos humanos, se aplicó un modelo in vitro compuesto enteramente de células mononucleares de sangre periférica humana expuestas a la cepa H37Ra (37º C, 5% CO2, por 5 dias). La formación de la agregación celular fue monitoreada día a día bajo microscopia óptica y tinción Zieh-Neelsen. Los granulomas fueron colectados a las 24 horas y el ARN extraído fue hibridizado con microarray de Affymetrix (Human Genome-U133 plus 2). Los datos de expresión de microarray fueron analizados con los programas dChiP y GenMAPP/MAPPFinder para determinar su significancia a nivel biológico, y los genes más relevantes se validaron a través de PCR en tiempo real. El examen microscópico revelo la formación gradual de granulomas y las bacterias ácidoalcohol resistentes fueron observadas entre y dentro de las células que formaban el granuloma. El análisis de los microarray mostró genes fuertemente expresados, comparados con los controles, los cuales incluyen receptores de superficie celular (ICAM1,2,3; FAS; IL-2R, TLR-4), citocinas pro inflamatorias (INF-g, TNF-alfa, IL-1, IL-6, IL-8), quimiocinas y sus receptores que no han sido previamente reportados (CCL2; CXCL2; CCL18; CXCR4; CCRL2), factores de trascripción (STAT4; STAT6), genes relacionados con la apoptosis y citotoxicidad (FAS, TRADD, granzima B, Granulisyn, Caspasa-8). La mayoría de los genes sub-expresados fueron relacionados con funciones metabólicas generales. Estos datos de expresión génica aportan evidencia que Mycobacterium tuberculosis produce una alteración global de la respuesta inmune del huésped infectado, y que una vez logremos armar el rompecabezas y logremos entenderlo podríamos valorar el desarrollo de nuevas terapias y quizás poder inhibir la reactivación de una infección latente. En este estudio demostramos que el análisis sistemático de la expresión génica en células infectadas con M. tuberculosis H37Ra reveló perfiles de expresión dirigidos a la activación de una respuesta inmune efectiva contra el bacilo, y que en estudios posteriores a este se puedan comparar con cepas clínicas de micobacteria con el fin de determinar eventos moleculares claves involucrados en la infección por M. tuberculosis.
Experimental Evidence for Gradient Length-Driven Electron Transport in Tokamaks
Creators: name: ASDEX Upgrade Team
name: Fahrbach, H.-U.
name: Leuterer, F.
name: Pereverzev, G.
name: Ryter, F.
name: Stober, J.
name: Suttrop, W.
Publisher: name: The American Physical Society
Year: 2001
Subjects: subject: 530

description: Physical Review Letters
The stratified homotopy type of the reductive Borel-Serre compactification
Creators: name: Jansen, Mikala Ørsnes
Publisher: name: arXiv
Year: 2020
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics

description: We identify the exit path $\infty$-category of the reductive Borel-Serre compactification as the nerve of a $1$-category defined purely in terms of rational parabolic subgroups and their unipotent radicals. As an immediate consequence, we identify the fundamental group of the reductive Borel-Serre compactification, recovering a result of Ji-Murty-Saper-Scherk, and we obtain a combinatorial incarnation of constructible complexes of sheaves on the reductive Borel-Serre compactification as elements in a derived functor category.
description: 47 pages, 1 figure, v2: minor revision, v3: final accepted version, some typos corrected
Constraining neutrino mass and extra relativistic degrees of freedom in dynamical dark energy models using Planck 2015 data in combination with low-redshift cosmological probes: basic extensions to $Λ$CDM cosmology
Creators: name: Zhao, Ming-Ming
name: Li, Yun-He
name: Zhang, Jing-Fei
name: Zhang, Xin
Publisher: name: arXiv
Year: 2016
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate how the properties of dark energy affect the cosmological measurements of neutrino mass and extra relativistic degrees of freedom. We limit ourselves to the most basic extensions of $Λ$ cold dark matter (CDM) model, i.e. the $w$CDM model with one additional parameter $w$, and the $w_{0}w_{a}$CDM model with two additional parameters, $w_{0}$ and $w_{a}$. In the cosmological fits, we employ the 2015 cosmic microwave background temperature and polarization data from the Planck mission, in combination with low-redshift measurements such as the baryon acoustic oscillations, Type Ia supernovae and the Hubble constant ($H_{0}$). Given effects of massive neutrinos on large-scale structure, we further include weak lensing, redshift space distortion, Sunyaev--Zeldovich cluster counts and Planck lensing data. We show that, though the cosmological constant $Λ$ is still consistent with the current data, a phantom dark energy ($w-1$) is slightly more favoured by current observations, which leads to the fact that in both $w$CDM and $w_0w_a$CDM models we obtain a larger upper limit of $\sum m_ν$. We also show that in the three dark energy models, the constraints on $N_{\rm eff}$ are in good accordance with each other, all in favour of the standard value 3.046, which indicates that the dark energy parameters almost have no impact on constraining $N_{\rm eff}$. Therefore, we conclude that the dark energy parameters can exert a significant influence on the cosmological weighing of neutrinos, but almost cannot affect the constraint on dark radiation.
description: 12 pages, 11 figures; accepted by MNRAS; match the publication version
La empresa comunitaria como alternativa para solucionar el desempleo en la ciudad de Cartagena
Creators: name: Ramos Diaz, Ines
name: Lopez A, Daisy
Publisher: name: Universidad de Cartagena
Year: 1987
Subjects: Desempleo

description: Tesis (Economista).--Universidad de Cartagena. Facultad de Ciencias Económicas. Programa de Economía.
description: El presente estudio tiene por objeto demostrar que la empresa comunitaria es una alternativa para solucionar el problema del desempleo.
Resolution of the identity approximation applied to PNOF correlation calculations
Creators: name: Lew-Yee, Juan Felipe Huan
name: Piris, Mario
name: del Campo, Jorge M.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: In this work, the required algebra to employ the resolution of the identity approximation within Piris Natural Orbital Functional (PNOF) is developed, leading to an implementation named DoNOF-RI. The arithmetic scaling is reduced from fifth-order to fourth-order, and the memory scaling is reduced from fourth-order to third-order, allowing significant computational time savings. After the DoNOF-RI calculation has fully converged, a restart with four-center electron repulsion integrals can be performed to remove the effect of the auxiliary basis set incompleteness, quickly converging to the exact result. The proposed approach has been tested on cycloalkanes and other molecules of general interest to study the numerical results as well as the speed-ups achieved by PNOF7-RI when compared with PNOF7.
description: 8 pages, 2 figures, 5 tables
title: Next-Generation-Sequencing in routine neuropathology diagnostics
Creators: name: Sahm, Felix
name: Schrimpf, Daniel
name: Meyer, Jochen
name: Jones, David
name: Reuss, David
name: Capper, David
name: Koelsche, Christian
name: Kratz, Annekathrin
name: Korshunov, Andrey
name: Zapatka, Mark
name: Pfister, Stefan
name: Unterberg, Andreas
name: Wick, Wolfgang
name: Von Deimling, Andreas
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: With the numbers of prognostic and predictive genetic markers in neuro-oncology steadily growing, the need for comprehensive molecular work-up of neuropathology samples has tremendously increased. Although several aberrations can be detected by immunohistochemistry (mutant IDH1R132H and BRAFV600E protein,[for full text, please go to the a.m. URL]
description: 60th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN)
La comunicación, una herramienta preventiva frente a situaciones conflictivas que se presentan al interior de las familias usuarias de los servicios del centro zonal industrial de la bahía, año 2008
Creators: name: Pérez Cera, Yuranis
Publisher: name: Facultad de Ciencias Sociales y Educación
Year: 2008
Subjects: subject: Trabajo social familiar
subject: Asistencia social familiar
subject: Familia y trabajo social

description: El proyecto estuvo encaminado a orientar, educar y sensibilizar a las familias hacia una adecuada comunicación familiar como herramienta fundamental para la solución y prevención de las distintas situaciones que se les presenten en las cuales el diálogo es fundamental para su solución. Uno de los propósitos de este proyecto fue facilitar espacios de reflexión en los que las familias rescataran los recursos con los que contaban para la solución de sus conflictos o simplemente para un mejor funcionamiento del núcleo familiar. Se tuvo como prioridad en el proyecto realizado la promoción del proceso de comunicación al interior de las familias como herramienta adecuada para el mejoramiento, solución y prevención de situaciones al interior de las mismas, teniendo como referencia que la falta o inadecuada comunicación en los hogares ha conllevado una ruptura en la triada madre, padre e hijos.
What drives passion? An empirical examination on the impact of personality trait interactions and job environments on work passion
Creators: name: Breu, Annika
name: Yasseri, Taha
Publisher: name: arXiv
Year: 2021
Subjects: subject: Social and Information Networks (cs.SI)
subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: Passionate employees are essential for organisational success as they foster higher performance and exhibit lower turnover or absenteeism. While a large body of research has investigated the consequences of passion, we know only little about its antecedents. Integrating trait interaction theory with trait activation theory, this paper examines how personality traits, i.e. conscientiousness, agreeableness, and neuroticism impact passion at work across different job situations. Passion has been conceptualized as a two-dimensional construct, consisting of harmonious work passion (HWP) and obsessive work passion (OWP). Our study is based on a sample of N = 824 participants from the myPersonality project. We find a positive relationship between neuroticism and OWP in enterprising environments. Further, we find a three-way interaction between conscientiousness, agreeableness, and enterprising environment in predicting OWP. Our findings imply that the impact of personality configurations on different forms of passion is contingent on the job environment. Moreover, in line with self-regulation theory, the results reveal agreeableness as a "cool influencer" and neuroticism as a "hot influencer" of the relationship between conscientiousness and work passion. We derive practical implications for organisations on how to foster work passion, particularly HWP, in organisations.
description: To Appear in Current Psychology
$\mathcal{O}$-operators and related structures on Leibniz algebras
Creators: name: Sun, Qinxiu
name: Jing, Naihuan
Publisher: name: arXiv
Year: 2020
Subjects: subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics
subject: 13D03, 16T10, 16B38

description: An $\mathcal{O}$-operator has been used to extend a Leibniz algebra by its representation. In this paper, we investigate several structures related to $\mathcal{O}$-operators on Leibniz algebras and introduce (dual) $\mathcal{O}$N-structures on Leibniz algebras associated to their representations. It is proved that $\mathcal{O}$-operators and dual $\mathcal{O}$N-structures generate each other under certain conditions. It is also shown that a solution of the strong Maurer-Cartan equation on the twilled Leibniz algebra gives rise to a dual $\mathcal{O}$N-structure. Finally, $r-n$ structures, RBN-structures and $\mathcal{B}N$-structures on Leibniz algebras are thoroughly studied and their interdependent relations are also studied.
description: 25 pages, new title
Optimal rates for the regularized learning algorithms under general source condition
Creators: name: Rastogi, Abhishake
name: Sampath, Sivananthan
Publisher: name: arXiv
Year: 2016
Subjects: subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: 68T05, 68Q32

description: We consider the learning algorithms under general source condition with the polynomial decay of the eigenvalues of the integral operator in vector-valued function setting. We discuss the upper convergence rates of Tikhonov regularizer under general source condition corresponding to increasing monotone index function. The convergence issues are studied for general regularization schemes by using the concept of operator monotone index functions in minimax setting. Further we also address the minimum possible error for any learning algorithm.
Assessing The Main Contributing Factores Of Cost Overrun: In The Case Of 20/80 Housing Program Of Addis Ababa City Adminstration
Creators: name: Adamu, Yohannes
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2018

description: Construction industry contributes significantly in improving socio-economic growth of a country. However, this industry usually faces chronic problems such as time overrun, cost overrun, poor quality and others. Of all these, cost overrun is a major problem that occurs globally including Ethiopia. Hence, this study focused on identifying the main contributing factors of cost overrun for 20/80 housing construction projects in the case of Addis Ababa City Administration. Data collection was done through structured questionnaire and office document review, which was designed based on 25 factors found from the literature. A total of 60 questionnaires were distributed to clients, consultants and contractors and 48 questionnaires were collected and which 44 responses were found valid. Descriptive statistics methods were employed through frequency Index/ mean score and average Index to understand the variables of cost overruns, the frequency of occurrence and significant impacts of each causative factor on the studied area. The findings from the study identified that, from 25 identified factors, only the most causative factors are 22 and the top five factors are Material shortage in the local market, delay preparation and approval of drawing, change order or rework, Labor cost increased due to environmental restriction, Change in foreign exchange rate/ for imported materials. Likewise, based on the possibility of occurrence the top five were identified, these are-payment delay for contractors, contractors financial difficulties, power interruption, incorrect quantity take-off, change in foreign exchange rate. Meanwhile, based on significant impacts of factors were identified. The most frequent way of using bidding methods in Addis Ababa housing program especially in 20/80 was open tendering. The overall effects that occurred in housing programs revealed through survey are – low productivity, project delay, low quality housing handover to beneficiaries or tenants, disputes among stakeholders E.T.C. Meanwhile, cost discrepancy of approved budget from actual cost for 20/80housing programs is 18.1%.
Gender Imbalance and Spatiotemporal Patterns of Contributions to Citizen Science Projects: the case of Zooniverse
Creators: name: Ibrahim, Khairunnisa
name: Khodursky, Samuel
name: Yasseri, Taha
Publisher: name: arXiv
Year: 2021
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Computers and Society (cs.CY)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Citizen Science is research undertaken by professional scientists and members of the public collaboratively. Despite numerous benefits of citizen science for both the advancement of science and the community of the citizen scientists, there is still no comprehensive knowledge of patterns of contributions, and the demography of contributors to citizen science projects. In this paper we provide a first overview of spatiotemporal and gender distribution of citizen science workforce by analyzing 54 million classifications contributed by more than 340 thousand citizen science volunteers from 198 countries to one of the largest citizen science platforms, Zooniverse. First we report on the uneven geographical distribution of the citizen scientist and model the variations among countries based on the socio-economic conditions as well as the level of research investment in each country. Analyzing the temporal features of contributions, we report on high "burstiness" of participation instances as well as the leisurely nature of participation suggested by the time of the day that the citizen scientists were the most active. Finally, we discuss the gender imbalance among citizen scientists (about 30% female) and compare it with other collaborative projects as well as the gender distribution in more formal scientific activities. Citizen science projects need further attention from outside of the academic community, and our findings can help attract the attention of public and private stakeholders, as well as to inform the design of the platforms and science policy making processes.
description: Under Review
MPEC 2023-S213 : 2023 SJ6
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 SJ6

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.