cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
SAV Operations on a Bus Line Corridor: Travel Demand, Service Frequency, and Vehicle Size
Creators: name: Yantao, H
name: Kockelman, KM
name: Truong, Long
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Before shared automated vehicles (SAVs) can be widely adopted, they are anticipated to be implemented commercially in confined regions or fixed routes where the benefits of automation can be realized. SAVs have the potential to operate in a traditional transit corridor, replacing conventional transit vehicles, and have frequent interactions with riders and other vehicles sharing the same right of way. This paper microsimulates SAVs' operation on a 6.5-mile corridor to understand how vehicle size and attributes of such SAV-based transit affect traffic, transit riders, and system costs. The SUMO (Simulation of Urban MObility) platform is employed to model microscopic interactions among SAVs, transit passengers, and other traffic. Results show that the use of smaller, but more frequent, SAVs leads to reduced passenger waiting times but increased vehicle travel times. More frequent services of smaller SAVs do not, in general, significantly affect general traffic due to shorter dwell times. Overall, using smaller SAVs instead of the large 40-seat SAVs can reduce system costs by up to 4% while also reducing passenger waiting times, under various demand levels and passenger loading factors. However, the use of 5-seat SAVs does not always have the lowest system costs.
Breastfeeding practices and problems among obese women compared with nonobese women in a Brazilian hospital
Creators: name: Perez, Marina Rico
name: de Castro, Lucíola Sant'Anna
name: Chang, Yan-Shing
name: Sañudo, Adriana
name: Marcacine, Karla Oliveira
name: Amir, Lisa
name: Ross, Michael G
name: Coca, Kelly Pereira
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Background: Women who are obese have lower rates of breastfeeding initiation and duration and are less likely to breastfeed exclusively compared with women who are not obese. To develop programs to improve breastfeeding practices among this group of women, we investigated the association between maternal obesity and breastfeeding practices and problems in the first days postpartum. Methods: We analyzed medical records from postpartum women at a rooming-in maternity ward in State of São Paulo, Brazil, between 2016 and 2018. We included those who had intended to exclusively breastfeed, had given birth to a singleton and were admitted to rooming-in. We analyzed exclusive breastfeeding and nonexclusive breastfeeding each day of hospitalization and the presence of breastfeeding problems, comparing women in the obese category (body mass index [BMI] ≥30 kg/m2) to normal and overweight women (≥18.6 to ≤29.9 kg/m2). Results: Two hundred and twenty-four postpartum women participated, including 86 women in the obese category. More than 50% of women with obesity reported a breastfeeding problem in the first and second postpartum days (p = 0.026 and p = 0.017, respectively) compared with the 41% and 38% nonobese group. Children of obese women were 2.8 times more likely to have poor latch during breastfeeding (95% confidence interval [CI]: 1.29-6.10) compared with the nonobese group on the third day. Conclusion: Maternal obesity increased the probability of breastfeeding difficulties and nonexclusive breastfeeding at discharge. Professionals need to support breastfeeding techniques in the days immediate after delivery to improve breastfeeding outcomes for mothers with obesity.
Additional file 1 of Rapid-cycle deliberate practice versus after-event debriefing clinical simulation in cardiopulmonary resuscitation: a cluster randomized trial
Creators: name: de Castro, Leandro Teixeira
name: Coriolano, Andreia Melo
name: Burckart, Karina
name: Soares, Mislane Bezerra
name: Accorsi, Tarso Augusto Duenhas
name: Rosa, Vitor Emer Egypto
name: de Santis Andrade Lopes, Antônio Sérgio
name: Couto, Thomaz Bittencourt
Publisher: name: figshare
Year: 2024
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1. Clinical scenario.
A new class of integrable maps of the plane: Manin transformations with involution curves
Creators: name: Van Der Kamp, Pieter
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 49
subject: Mathematical sciences
classificationCode: 4901
subject: Applied mathematics
classificationCode: 4904
subject: Pure mathematics

description: For cubic pencils we define the notion of an involution curve. This is a curve which intersects each curve of the pencil in exactly one non-base point of the pencil. Involution curves can be used to construct integrable maps of the plane which leave invariant a cubic pencil.
Elevated circulating and placental SPINT2 is associated with placental dysfunction
Creators: name: Murphy, CN
name: Walker, SP
name: Macdonald, TM
name: Keenan, E
name: Hannan, NJ
name: Wlodek, Mary
name: Myers, J
name: Briffa, JF
name: Stasis, Tania
name: Mitchell, A Roddy
name: Whigham, CA
name: Cannon, P
name: Nguyen, TV
name: Kandel, M
name: Pritchard, N
name: Tong, S
name: Kaitu’u-lino, TJ
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Biomarkers for placental dysfunction are currently lacking. We recently identified SPINT1 as a novel biomarker; SPINT2 is a functionally related placental protease inhibitor. This study aimed to characterise SPINT2 expression in placental insufficiency. Circulating SPINT2 was assessed in three prospective cohorts, collected at the following: (1) term delivery (n = 227), (2) 36 weeks (n = 364), and (3) 24–34 weeks’ (n = 294) gestation. SPINT2 was also measured in the plasma and placentas of women with established placental disease at preterm (<34 weeks) delivery. Using first-tri-mester human trophoblast stem cells, SPINT2 expression was assessed in hypoxia/normoxia (1% vs. 8% O2), and following inflammatory cytokine treatment (TNFα, IL-6). Placental SPINT2 mRNA was measured in a rat model of late-gestational foetal growth restriction. At 36 weeks, circulating SPINT2 was elevated in patients who later developed preeclampsia (p = 0.028; median = 2233 pg/mL vs. controls, median = 1644 pg/mL), or delivered a small-for-gestational-age infant (p = 0.002; median = 2109 pg/mL vs. controls, median = 1614 pg/mL). SPINT2 was elevated in the placentas of patients who required delivery for preterm preeclampsia (p = 0.025). Though inflammatory cytokines had no effect, hypoxia increased SPINT2 in cytotrophoblast stem cells, and its expression was elevated in the placental labyrinth of growth-restricted rats. These findings suggest elevated SPINT2 is associated with placental insufficiency.
Supplemental Material, sj-pdf-1-ppq-10.1177_1354068818793915 - Party system erosion: Evidence from Peru
Creators: name: Carter, Christopher L
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material, sj-pdf-1-ppq-10.1177_1354068818793915 for Party system erosion: Evidence from Peru by Christopher L Carter in Party Politics
Supplemental Material, sj-docx-1-ppq-10.1177_1354068818795195 - Why, sometimes, primaries? Intraparty democratization as a default selection mechanism in German and Spanish mainstream parties
Creators: name: Astudillo, Javier
name: Detterbeck, Klaus
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material, sj-docx-1-ppq-10.1177_1354068818795195 for Why, sometimes, primaries? Intraparty democratization as a default selection mechanism in German and Spanish mainstream parties by Javier Astudillo and Klaus Detterbeck in Party Politics
Supplemental Material, pp-2017-0221-File004 - Why, sometimes, primaries? Intraparty democratization as a default selection mechanism in German and Spanish mainstream parties
Creators: name: Astudillo, Javier
name: Detterbeck, Klaus
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material, pp-2017-0221-File004 for Why, sometimes, primaries? Intraparty democratization as a default selection mechanism in German and Spanish mainstream parties by Javier Astudillo, and Klaus Detterbeck in Party Politics
Gene network analysis to determine the effect of hypoxia-associated genes on brain damages and tumorigenesis using an avian model
Creators: name: Kharrati-Koopaee, H
name: Ebrahimie, Esmaeil
name: Dadpasand, M
name: Niazi, A
name: Tian, R
name: Esmailizadeh, A
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Background: Hypoxia refers to the condition of low oxygen pressure in the atmosphere and characterization of response to hypoxia as a biological complex puzzle, is challenging. Previously, we carried out a comparative genomic study by whole genome resequencing of highland and lowland Iranian native chickens to identify genomic variants associated with hypoxia conditions. Based on our previous findings, we used chicken as a model and the identified hypoxia-associated genes were converted to human’s orthologs genes to construct the informative gene network. The main goal of this study was to visualize the features of diseases due to hypoxia-associated genes by gene network analysis. Results: It was found that hypoxia-associated genes contained several gene networks of disorders such as Parkinson, Alzheimer, cardiomyopathy, drug toxicity, and cancers. We found that biological pathways are involved in mitochondrion dysfunctions including peroxynitrous acid production denoted in brain injuries. Lewy body and neuromelanin were reported as key symptoms in Parkinson disease. Furthermore, calmodulin, and amyloid precursor protein were detected as leader proteins in Alzheimer’s diseases. Dexamethasone was reported as the candidate toxic drug under the hypoxia condition that implicates diabetes, osteoporosis, and neurotoxicity. Our results suggested DNA damages caused by the high doses of UV radiation in high-altitude conditions, were associated with breast cancer, ovarian cancer, and colorectal cancer. Conclusions: Our results showed that hypoxia-associated genes were enriched in several gene networks of disorders including Parkinson, Alzheimer, cardiomyopathy, drug toxicity, and different types of cancers. Furthermore, we suggested, UV radiation and low oxygen conditions in high-altitude regions may be responsible for the variety of human diseases.
Genetic parameters of blood urea nitrogen and milk urea nitrogen concentration in dairy cattle managed in pasture-based production systems of New Zealand and Australia
Creators: name: Van Den Berg, I
name: Ho, PN
name: Haile-Mariam, Mekonnen
name: Beatson, PR
name: O'Connor, E
name: Pryce, Jennie
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 30
subject: Agricultural, veterinary and food sciences
classificationCode: 3003
subject: Animal production
classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 41
subject: Environmental sciences

description: Context: Urinary nitrogen excretion by grazing cattle causes environmental pollution. Selecting for cows with a lower concentration of urinary nitrogen excretion may reduce the environmental impact. While urinary nitrogen excretion is difficult to measure, blood urea nitrogen (BUN), mid-infrared spectroscopy (MIR)-predicted BUN (MBUN), which is predicted from MIR spectra measured on milk samples, and milk urea nitrogen (MUN) are potential indicator traits. Australia and New Zealand have increasing datasets of cows with urea records, with 18 120 and 15 754 cows with urea records in Australia and New Zealand respectively. A collaboration between Australia and New Zealand could further increase the size of the dataset by sharing data. Aims: Our aims were to estimate genetic parameters for urea traits within country, and genetic correlations between countries to gauge the benefit of having a joint reference population for genomic prediction of an indicator trait that is potentially suitable for selection to reduce urinary nitrogen excretion for both countries. Methods: Genetic parameters were estimated within country (Australia and New Zealand) in Holstein, Jersey and a multibreed population, for BUN, MBUN and MUN in Australia and MUN in New Zealand, using high-density genotypes. Genetic correlations were also estimated between the urea traits recorded in Australia and MUN in New Zealand. Analyses used the first record available for each cow or within days-in-milk (DIM) intervals. Key results: Heritabilities ranged from 0.08 to 0.32 for the various urea traits. Higher heritabilities were obtained for Jersey than for Holstein, and for the New Zealand cows than for the Australian cows. While urea traits were highly correlated within Australia (0.71-0.94), genetic correlations between Australia and New Zealand were small to moderate (0.08-0.58). Conclusions: Our results showed that the heritability for urea traits differs among trait, breed, and country. While urea traits are highly correlated within country, genetic correlations between urea traits in Australia and MUN in New Zealand were only low to moderate. Implications: Further study is required to identify the underlying causes of the difference in heritabilities observed, to compare the accuracies of different reference populations, and to estimate genetic correlations between urea traits and other traits such as fertility and feed intake. Larger datasets may help estimate genetic correlations more accurately between countries.
Supplemental Material, insurgent_terrorism_appendix_august_2018 - Carrots, Sticks, and Insurgent Targeting of Civilians
Creators: name: Asal, Victor
name: Phillips, Brian J.
name: R. Karl Rethemeyer
name: Simonelli, Corina
name: Young, Joseph K.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 220104 Human Rights and Justice Issues
subject: FOS: Philosophy, ethics and religion
subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material, insurgent_terrorism_appendix_august_2018 for Carrots, Sticks, and Insurgent Targeting of Civilians by Victor Asal, Brian J. Phillips, R. Karl Rethemeyer, Corina Simonelli, and Joseph K. Young in Journal of Conflict Resolution
Genetic parameters of blood urea nitrogen and milk urea nitrogen concentration in dairy cattle managed in pasture-based production systems of New Zealand and Australia
Creators: name: Van Den Berg, I
name: Ho, PN
name: Haile-Mariam, M
name: Beatson, PR
name: O'Connor, E
name: Pryce, Jennie
Publisher: name: La Trobe
Year: 2022

description: Context: Urinary nitrogen excretion by grazing cattle causes environmental pollution. Selecting for cows with a lower concentration of urinary nitrogen excretion may reduce the environmental impact. While urinary nitrogen excretion is difficult to measure, blood urea nitrogen (BUN), mid-infrared spectroscopy (MIR)-predicted BUN (MBUN), which is predicted from MIR spectra measured on milk samples, and milk urea nitrogen (MUN) are potential indicator traits. Australia and New Zealand have increasing datasets of cows with urea records, with 18 120 and 15 754 cows with urea records in Australia and New Zealand respectively. A collaboration between Australia and New Zealand could further increase the size of the dataset by sharing data. Aims: Our aims were to estimate genetic parameters for urea traits within country, and genetic correlations between countries to gauge the benefit of having a joint reference population for genomic prediction of an indicator trait that is potentially suitable for selection to reduce urinary nitrogen excretion for both countries. Methods: Genetic parameters were estimated within country (Australia and New Zealand) in Holstein, Jersey and a multibreed population, for BUN, MBUN and MUN in Australia and MUN in New Zealand, using high-density genotypes. Genetic correlations were also estimated between the urea traits recorded in Australia and MUN in New Zealand. Analyses used the first record available for each cow or within days-in-milk (DIM) intervals. Key results: Heritabilities ranged from 0.08 to 0.32 for the various urea traits. Higher heritabilities were obtained for Jersey than for Holstein, and for the New Zealand cows than for the Australian cows. While urea traits were highly correlated within Australia (0.71-0.94), genetic correlations between Australia and New Zealand were small to moderate (0.08-0.58). Conclusions: Our results showed that the heritability for urea traits differs among trait, breed, and country. While urea traits are highly correlated within country, genetic correlations between urea traits in Australia and MUN in New Zealand were only low to moderate. Implications: Further study is required to identify the underlying causes of the difference in heritabilities observed, to compare the accuracies of different reference populations, and to estimate genetic correlations between urea traits and other traits such as fertility and feed intake. Larger datasets may help estimate genetic correlations more accurately between countries.
A conditional multi-trait sequence GWAS discovers pleiotropic candidate genes and variants for sheep wool, skin wrinkle and breech cover traits
Creators: name: Bolormaa, Sunduimijid
name: Swan, Andrew A
name: Stothard, Paul
name: Khansefid, Majid
name: Moghaddar, Nasir
name: Duijvesteijn, Naomi
name: van der Werf, Julius HJ
name: Daetwyler, Hans
name: MacLeod, Iona
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3105
subject: Genetics

description: Abstract
 Background
 Imputation to whole-genome sequence is now possible in large sheep populations. It is therefore of interest to use this data in genome-wide association studies (GWAS) to investigate putative causal variants and genes that underpin economically important traits. Merino wool is globally sought after for luxury fabrics, but some key wool quality attributes are unfavourably correlated with the characteristic skin wrinkle of Merinos. In turn, skin wrinkle is strongly linked to susceptibility to “fly strike” (Cutaneous myiasis), which is a major welfare issue. Here, we use whole-genome sequence data in a multi-trait GWAS to identify pleiotropic putative causal variants and genes associated with changes in key wool traits and skin wrinkle.

 Results
 A stepwise conditional multi-trait GWAS (CM-GWAS) identified putative causal variants and related genes from 178 independent quantitative trait loci (QTL) of 16 wool and skin wrinkle traits, measured on up to 7218 Merino sheep with 31 million imputed whole-genome sequence (WGS) genotypes. Novel candidate gene findings included the MAT1A gene that encodes an enzyme involved in the sulphur metabolism pathway critical to production of wool proteins, and the ESRP1 gene. We also discovered a significant wrinkle variant upstream of the HAS2 gene, which in dogs is associated with the exaggerated skin folds in the Shar-Pei breed.

 Conclusions
 The wool and skin wrinkle traits studied here appear to be highly polygenic with many putative candidate variants showing considerable pleiotropy. Our CM-GWAS identified many highly plausible candidate genes for wool traits as well as breech wrinkle and breech area wool cover.
A conditional multi-trait sequence GWAS discovers pleiotropic candidate genes and variants for sheep wool, skin wrinkle and breech cover traits
Creators: name: Bolormaa, Sunduimijid
name: Swan, Andrew A
name: Stothard, Paul
name: Khansefid, Majid
name: Moghaddar, Nasir
name: Duijvesteijn, Naomi
name: van der Werf, Julius HJ
name: Daetwyler, Hans
name: MacLeod, Iona M
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Abstract Background Imputation to whole-genome sequence is now possible in large sheep populations. It is therefore of interest to use this data in genome-wide association studies (GWAS) to investigate putative causal variants and genes that underpin economically important traits. Merino wool is globally sought after for luxury fabrics, but some key wool quality attributes are unfavourably correlated with the characteristic skin wrinkle of Merinos. In turn, skin wrinkle is strongly linked to susceptibility to “fly strike” (Cutaneous myiasis), which is a major welfare issue. Here, we use whole-genome sequence data in a multi-trait GWAS to identify pleiotropic putative causal variants and genes associated with changes in key wool traits and skin wrinkle. Results A stepwise conditional multi-trait GWAS (CM-GWAS) identified putative causal variants and related genes from 178 independent quantitative trait loci (QTL) of 16 wool and skin wrinkle traits, measured on up to 7218 Merino sheep with 31 million imputed whole-genome sequence (WGS) genotypes. Novel candidate gene findings included the MAT1A gene that encodes an enzyme involved in the sulphur metabolism pathway critical to production of wool proteins, and the ESRP1 gene. We also discovered a significant wrinkle variant upstream of the HAS2 gene, which in dogs is associated with the exaggerated skin folds in the Shar-Pei breed. Conclusions The wool and skin wrinkle traits studied here appear to be highly polygenic with many putative candidate variants showing considerable pleiotropy. Our CM-GWAS identified many highly plausible candidate genes for wool traits as well as breech wrinkle and breech area wool cover.
Table_1_SUPPLEMENT – Supplemental material for From Qualitative Meta-Summary to Qualitative Meta-Synthesis: Introducing a New Situation-Specific Theory of Barriers and Facilitators for Self-Care in Patients With Heart Failure
Creators: name: Herber, Oliver Rudolf
name: Kastaun, Sabrina
name: Wilm, Stefan
name: Barroso, Julie
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, Table_1_SUPPLEMENT for From Qualitative Meta-Summary to Qualitative Meta-Synthesis: Introducing a New Situation-Specific Theory of Barriers and Facilitators for Self-Care in Patients With Heart Failure by Oliver Rudolf Herber, Sabrina Kastaun, Stefan Wilm and Julie Barroso in Qualitative Health Research
Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation
Creators: name: Medina, CB
name: Chiu, YH
name: Stremska, ME
name: Lucas, CD
name: Poon, Ivan
name: Tung, KS
name: Elliott, MR
name: Desai, B
name: Lorenz, UM
name: Bayliss, DA
name: Ravichandran, KS
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Allergic airway inflammation is driven by type-2 CD4+ T cell inflammatory responses. We uncover an immunoregulatory role for the nucleotide release channel, Panx1, in T cell crosstalk during airway disease. Inverse correlations between Panx1 and asthmatics and our mouse models revealed the necessity, specificity, and sufficiency of Panx1 in T cells to restrict inflammation. Global Panx1−/− mice experienced exacerbated airway inflammation, and T-cell-specific deletion phenocopied Panx1−/− mice. A transgenic designed to re-express Panx1 in T cells reversed disease severity in global Panx1−/− mice. Panx1 activation occurred in pro-inflammatory T effector (Teff) and inhibitory T regulatory (Treg) cells and mediated the extracellular-nucleotide-based Treg-Teff crosstalk required for suppression of Teff cell proliferation. Mechanistic studies identified a Salt-inducible kinase-dependent phosphorylation of Panx1 serine 205 important for channel activation. A genetically targeted mouse expressing non-phosphorylatable Panx1S205A phenocopied the exacerbated inflammation in Panx1−/− mice. These data identify Panx1-dependent Treg:Teff cell communication in restricting airway disease.
Rate of decline in kidney function and known age-of-onset or duration of type 2 diabetes
Creators: name: Buyadaa, O
name: Salim, Agus
name: Morton, JI
name: Magliano, Dianna
name: Shaw, Jonathan
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3202
subject: Clinical sciences

description: The association between rate of kidney function decline and age-of-onset or duration of diabetes has not been well investigated. We aimed to examine whether rates of estimated glomerular filtration rate (eGFR) decline differ by age-of-onset or duration in people with type 2 diabetes. Using the Action to Control Cardiovascular Risk in Diabetes study which included those with HbA1c ≥ 7.5% and who were at high risk of cardiovascular events, rates of eGFR decline were calculated and were compared among groups defined by the known age-of-onset (0–39, 40–49, 50–59, 60–69 and > 70 years) and 5-year diabetes duration intervals. Changes in renal function were evaluated using median of 6 (interquartile range 3–10) eGFR measurements per person. eGFR decline was the slowest in those with known age-at-diagnosis of 50–59 years or those with duration of diabetes < 5 years. The rates of eGFR decline were significantly greater in those with known age-of-onset < 40 years or those with duration of diabetes > 20 years compared to those diagnosed at 50–59 or those with duration of diabetes < 5 years (− 1.98 vs − 1.61 mL/min/year; − 1.82 vs − 1.52 mL/min/year; respectively (p < 0.001). Those with youngest age-of-onset or longer duration of diabetes had more rapid declines in eGFR compared to those diagnosed at middle age or those with shorter duration of diabetes.
Rate of decline in kidney function and known age-of-onset or duration of type 2 diabetes
Creators: name: Buyadaa, O
name: Salim, Agus
name: Morton, JI
name: Magliano, DJ
name: Shaw, Jonathan
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: The association between rate of kidney function decline and age-of-onset or duration of diabetes has not been well investigated. We aimed to examine whether rates of estimated glomerular filtration rate (eGFR) decline differ by age-of-onset or duration in people with type 2 diabetes. Using the Action to Control Cardiovascular Risk in Diabetes study which included those with HbA1c ≥ 7.5% and who were at high risk of cardiovascular events, rates of eGFR decline were calculated and were compared among groups defined by the known age-of-onset (0–39, 40–49, 50–59, 60–69 and > 70 years) and 5-year diabetes duration intervals. Changes in renal function were evaluated using median of 6 (interquartile range 3–10) eGFR measurements per person. eGFR decline was the slowest in those with known age-at-diagnosis of 50–59 years or those with duration of diabetes < 5 years. The rates of eGFR decline were significantly greater in those with known age-of-onset < 40 years or those with duration of diabetes > 20 years compared to those diagnosed at 50–59 or those with duration of diabetes < 5 years (− 1.98 vs − 1.61 mL/min/year; − 1.82 vs − 1.52 mL/min/year; respectively (p < 0.001). Those with youngest age-of-onset or longer duration of diabetes had more rapid declines in eGFR compared to those diagnosed at middle age or those with shorter duration of diabetes.
Radiofrequency ablation of hepatocellular carcinoma close to stomach with balloon interposition
Creators: name: Shriduth, Premshanker
Publisher: name: EURORAD
Year: 2016
Subjects: subject: Interventional non-vascular
subject: Percutaneous
subject: Ablation procedures
subject: Neoplasia

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: female, 45 years
description: Clinical History: A 45 yr old male with history of chronic liver disease underwent an ultrasound abdomen which showed a mass in left lobe, following which he underwent a computed tomography (CT) outside consistent with hepatocellular carcinoma (HCC). He was referred for ra... Final Diagnosis: Successful radiofrequency ablation of high-risk location HCC with balloon interposition
MPEC 2024-P148 : 2024 PW3
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 PW3

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Additional file 1 of Computerized clinical decision support systems for prescribing in primary care: main characteristics and implementation impact—protocol of an evidence and gap map
Creators: name: Acosta-García, Héctor
name: Ferrer-López, Ingrid
name: Ruano-Ruiz, Juan
name: Santos-Ramos, Bernardo
name: Molina-López, Teresa
Publisher: name: figshare
Year: 2024
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences

description: Additional file 1. Databases Search strategies.
A Survey of university course timetabling problem: perspectives, trends and opportunities
Creators: name: Chen, Mei Ching
name: San Nah Sze
name: Goh, Say Leng
name: Sabar, Nasser
name: Kendall, Graham
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: The timetabling problem is common to academic institutions such as schools, colleges or universities. It is a very hard combinatorial optimisation problem which attracts the interest of many researchers. The university course timetabling problem (UCTTP) is difficult to address due to the size of the problem and several challenging hard and soft constraints. Over the years, various methodologies were proposed to solve UCTTP. The purpose of this survey paper is to provide the most recent scientific review of the methodologies applied to UCTTP. The paper unveils a classification of methodologies proposed in recent years based on chronology and datasets used. Perspectives, trends, challenges and opportunities in UCTTP are also presented. It is observed that meta-heuristic approaches are popular among researchers. This is followed closely by hybrid methodologies. Hyper-heuristic approaches are also able to produce effective results. Another observation is that the state-of-art methodologies in the scientific literature are not fully utilised in a real-world environment perhaps due to the limited flexibility of these methodologies.
Evaluation of an Aboriginal and Torres Strait Islander strengths based coaching program: a study protocol
Creators: name: Brown, Alison
name: Mensah, Fiona
name: Gee, Graham
name: Paradies, Yin
name: French, Samantha
name: Waters, Lea
name: Arabena, Kerry
name: Armstrong, Gregory
name: Nicholson, Jan
name: Brown, Stephanie J
name: Hegarty, Kelsey
name: Ritte, Rebecca
name: Meiselbach, Kristy
name: Kelaher, Margaret
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Abstract Background Increasingly, strength-based approaches to health and wellbeing interventions with Aboriginal and Torres Strait Islander Australians are being explored. This is a welcome counter to deficit-based initiatives which can represent a non-Indigenous view of outcomes of interest. However, the evidence base is not well developed. This paper presents the protocol for evaluating a strengths-based initiative which provides life coaching services to Aboriginal and Torres Strait Islander community housing tenants. The study aims to evaluate the effect of life coaching on social and emotional wellbeing (SEWB) of tenants in three Victorian regions. Methods The More Than a Landlord (MTAL) study is a prospective cohort study of Aboriginal Housing Victoria tenants aged 16 years and over that embeds the evaluation of a life coaching program. All tenant holders in one metropolitan and two regional areas of Victoria are invited to participate in a survey of SEWB, containing items consistent with key categories of SEWB as understood and defined by Aboriginal and Torres Strait Islander peoples, and key demographics, administered by Aboriginal and Torres Strait Islander peer researchers at baseline, 6 and 18 months. Survey participants are then invited to participate in strengths based life coaching, using the GROW model, for a duration of up to 18 months. Indigenous life coaches provide tenants with structured support in identifying and making progress towards their goals and aspirations, rather than needs. The study aims to recruit a minimum of 200 survey participants of which it is anticipated that approximately 73% will agree to life coaching. Discussion The MTAL study is a response to Aboriginal and Torres Strait Islander community and organisational requests to build the evidence base for an initiative originally developed and piloted within an Aboriginal controlled organisation. The study design aligns with key principles for research in Indigenous communities in promoting control, decision making and capacity building. The MTAL study will provide essential evidence to evaluate the effectiveness of strengths-based initiatives in promoting SEWB in these communities and provide new evidence about the relationship between strengths, resilience, self-determination and wellbeing outcomes. Trial registration This trial was retrospectively registered with the ISRCTN Register on the 12/7/21 with the study ID:ISRCTN33665735.
Additional file 2 of Computerized clinical decision support systems for prescribing in primary care: main characteristics and implementation impact—protocol of an evidence and gap map
Creators: name: Acosta-García, Héctor
name: Ferrer-López, Ingrid
name: Ruano-Ruiz, Juan
name: Santos-Ramos, Bernardo
name: Molina-López, Teresa
Publisher: name: figshare
Year: 2024
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences

description: Additional file 2. Example of Evidence and Gaps Maps.
Allelic Variation in Protein Tyrosine Phosphatase Receptor Type-C in Cattle Influences Erythrocyte, Leukocyte and Humoral Responses to Infestation With the Cattle Tick Rhipicephalus australis
Creators: name: Jonsson, NN
name: Cox, DK
name: Piper, EK
name: Valdivieso, EFM
name: Constantinoiu, C
name: Jackson, LA
name: Stear, Michael
name: Ross, EM
name: Tabor, AE
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: The protein tyrosine phosphatase receptor type-C (PTPRC) gene encodes the common leukocyte antigen (CD45) receptor. CD45 affects cell adhesion, migration, cytokine signalling, cell development, and activation state. Four families of the gene have been identified in cattle: a taurine group (Family 1), two indicine groups (Families 2 and 4) and an African “taurindicine” group (Family 3). Host resistance in cattle to infestation with ticks is moderately heritable and primarily manifests as prevention of attachment and feeding by larvae. This study was conducted to describe the effects of PTPRC genotype on immune-response phenotypes in cattle that display a variable immune responsiveness to ticks. Thirty tick-naïve Santa-Gertrudis cattle (a stabilized composite of 5/8 taurine and 3/8 indicine) were artificially infested with ticks weekly for 13 weeks and ranked according to their tick counts. Blood samples were taken from control and tick-challenged cattle immediately before, then at 21 d after infestation and each subsequent week for 9 weeks. Assays included erythrocyte profiles, white blood cell counts, the percentage of cellular subsets comprising the peripheral blood mononuclear cell (PBMC) population, and the ability of PBMC to recognize and proliferate in response to stimulation with tick antigens in vitro. The cattle were PTPRC genotyped using a RFLP assay that differentiated Family 1 and 3 together (220 bp), from Family 2 (462 bp), and from Family 4 (486 bp). The PTPRC allele frequencies were Family 1/3 = 0.34; Family 2 = 0.47; Family 4 = 0.19. There was no significant association between PTPRC genotype and tick count. Each copy of the Family 1/3 allele significantly decreased total leucocyte count (WCC) and CD8+ cells. Increasing dosage of Family 2 alleles significantly increased red blood cell count (RCC), haematocrit (PCV), and haemoglobin (Hb) concentration in blood. Increasing dosage of the Family 4 allele was associated with increased WCC, reduced RCC, reduced PCV and reduced Hb. Homozygote Family 1/3 animals had consistently lower IgG1 in response to tick Ag than homozygote Family 2 animals. The PTPRC genotype influences the bovine immune response to ticks but was not associated with the observed variation in resistance to tick infestation in this study.
Supplemental Material, SPPS801003_suppl_mat - Cultural Patterns Explain the Worldwide Perception/Performance Paradox in Student Self-Assessments of Math and Science Skill
Creators: name: Sanchez, Carmen
name: Dunning, David
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental Material, SPPS801003_suppl_mat for Cultural Patterns Explain the Worldwide Perception/Performance Paradox in Student Self-Assessments of Math and Science Skill by Carmen Sanchez, and David Dunning in Social Psychological and Personality Science
Sequence-based genome-wide association study of individual milk mid-infrared wavenumbers in mixed-breed dairy cattle
Creators: name: Tiplady, KM
name: Lopdell, TJ
name: Reynolds, E
name: Sherlock, RG
name: Keehan, M
name: Johnson, TJ
name: Pryce, Jennie
name: Davis, SR
name: Spelman, RJ
name: Harris, BL
name: Garrick, DJ
name: Littlejohn, MD
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Background: Fourier-transform mid-infrared (FT-MIR) spectroscopy provides a high-throughput and inexpensive method for predicting milk composition and other novel traits from milk samples. While there have been many genome-wide association studies (GWAS) conducted on FT-MIR predicted traits, there have been few GWAS for individual FT-MIR wavenumbers. Using imputed whole-genome sequence for 38,085 mixed-breed New Zealand dairy cattle, we conducted GWAS on 895 individual FT-MIR wavenumber phenotypes, and assessed the value of these direct phenotypes for identifying candidate causal genes and variants, and improving our understanding of the physico-chemical properties of milk. Results: Separate GWAS conducted for each of 895 individual FT-MIR wavenumber phenotypes, identified 450 1-Mbp genomic regions with significant FT-MIR wavenumber QTL, compared to 246 1-Mbp genomic regions with QTL identified for FT-MIR predicted milk composition traits. Use of mammary RNA-seq data and gene annotation information identified 38 co-localized and co-segregating expression QTL (eQTL), and 31 protein-sequence mutations for FT-MIR wavenumber phenotypes, the latter including a null mutation in the ABO gene that has a potential role in changing milk oligosaccharide profiles. For the candidate causative genes implicated in these analyses, we examined the strength of association between relevant loci and each wavenumber across the mid-infrared spectrum. This revealed shared association patterns for groups of genomically-distant loci, highlighting clusters of loci linked through their biological roles in lactation and their presumed impacts on the chemical composition of milk. Conclusions: This study demonstrates the utility of FT-MIR wavenumber phenotypes for improving our understanding of milk composition, presenting a larger number of QTL and putative causative genes and variants than found from FT-MIR predicted composition traits. Examining patterns of significance across the mid-infrared spectrum for loci of interest further highlighted commonalities of association, which likely reflects the physico-chemical properties of milk constituents.
Additional file 1 of Evaluation of a public COVID-19 dashboard in the Western Cape, South Africa: a tool for communication, trust, and transparency
Creators: name: Ismail, Muzzammil
name: Morden, Erna
name: Hussey, Hannah
name: Paleker, Masudah
name: Jacobs, Theuns
name: Laenen, Inneke
name: Hunter, Mehreen
name: Moodley, Melvin
name: Smith, Mariette
name: Mutemaringa, Themba
name: Bam, Jamy-Lee
name: Dane, Pierre
name: Heekes, Alexa
name: Boulle, Andrew
name: Davies, Mary-Ann
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology

description: Additional file 1: Supplementary Table 1. Questionnaire with possible response options. Supplementary Table 2. Number of views by continental region. Supplementary Table 3. Number of views per day by COVID-19 period (30 April 2020 – 29 April 2021). Supplementary Figure 1. Number of views per day by COVID-19 wave period. Supplementary Figure 2. Median number of views by day of week. Supplementary Figure 3. Number of views per day by weekday vs weekend*. Supplementary Table 4. Reported devices used by occupational status* (n=794). Supplementary Table 5. Reported frequency of use by age category* (n=794). Supplementary Table 6. Reported impact on personal planning and behaviour by element most often used* (n=794). Supplementary Table 7. Reported purpose of dashboard for participants* (n=1279).
title: Quelles stratégies individualisées mettre en place en vue d’améliorer la littératie en santé des patients requérants d’asile en Suisse ?
title: Le cas de l’hépatite B
titleType: Subtitle
Creators: name: Piquet, Joycia
name: Polli, Anaïs
Publisher: name: Unknown
Year: 0
Subjects: subject: Requérants d’asile
subject: Population vulnérable
subject: Hépatite B
subject: Littératie en santé
subject: Qualité de vie
subject: hesav TB SI

description: Contexte : Les requérants d’asile nécessitent des soins culturellement et individuellement adaptés. Leurs vulnérabilités et niveaux de littératie en santé représentent un enjeu pour les soins infirmiers. L’hépatite B est emblématique dans leurs prises en charge, car il s’agit d’un des défis de santé publique. Objectif : Identifier les stratégies individualisées en vue d’améliorer la littératie en santé des patients requérants d’asile en Suisse potentiellement atteints d’hépatite B. Méthode : Réalisation d’une revue de littérature basée sur 6 études sélectionnées dans CINHAL et PubMed. Celles-ci sont datées de moins de 10 ans, écrites en français et en anglais. La population cible est constituée des requérants d’asile et âgée d’au moins 18 ans. Les articles ont été analysés avec la grille de Fortin & Gagnon (2016) et les résultats structurés selon la théorie Transcultural Nursing Theory de Madeleine Leininger. Résultats : Nombreux facteurs influencent la littératie en santé des requérants d’asile. Ce sont les déterminants sociaux de la santé : l’âge, la culture, le niveau d’éducation, le mode et la condition de vie, le niveau socio-économique et le système politique. La littératie en santé a une influence sur leurs perceptions de la santé physique et psychique. Conclusion : La prise en charge des requérants d’asile doit être individualisée par des équipes multidisciplinaires afin de prendre en compte toutes les problématiques auxquelles ils sont confrontés.
Including milk production, conformation, and functional traits in multivariate models for genetic evaluation of lameness
Creators: name: Khansefid, Majid
name: Haile-Mariam, Mekonnen
name: Pryce, Jennie
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 30
subject: Agricultural, veterinary and food sciences
classificationCode: 3003
subject: Animal production
classificationCode: 3006
subject: Food sciences
classificationCode: 3009
subject: Veterinary sciences
subject: FOS: Veterinary sciences

description: Lameness is a serious health and welfare issue that can negatively affect the economic performance of cows, especially on pasture-based dairy farms. However, most genetic predictions (GP) of lameness have low accuracy because lameness data are often incomplete as data are collected voluntarily by farmers in countries such as Australia. The objective of this study was to find routinely measured traits that are correlated with lameness and use them in multivariate evaluation models to improve the accuracy of GP for lameness. We used health events and treatments associated with lameness recorded by Australian farmers from 2002 to early 2019. The lameness incidence rates in Holstein and Jersey cows were 3.3% and 4.6%, respectively. We analyzed the records of 36 other traits (milk production, conformation, fertility, and survival traits) to estimate genetic correlations with lameness. The estimated heritability ± standard error (and repeatability ± standard error) for lameness in both Holstein and Jersey breeds were very low: 0.007 ± 0.002 (and 0.029 ± 0.002) and 0.005 ± 0.003 (and 0.027 ± 0.006), respectively, in univariate sire models. For the GP models, we tested including measurements of overall type to prediction models for Holsteins, stature and body length for Jersey, and milk yield and fertility traits for both breeds. The average accuracy of GP, calculated from prediction error variances, were 0.38 and 0.24 for Holstein and Jersey sires, respectively, when estimated using univariate sire models and both increased to 0.43 using multivariate sire models. In conclusion, we found that the accuracy of GP for lameness could be improved by including genetically correlated traits in a multivariate model. However, to further improve the accuracy of predictions of lameness, precise identification and recording incidences of hoof or leg disorder, or large-scale recording of locomotion and claw scores by trained personnel should be considered.
Including milk production, conformation, and functional traits in multivariate models for genetic evaluation of lameness
Creators: name: Khansefid, M
name: Haile-Mariam, M
name: Pryce, Jennie
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Lameness is a serious health and welfare issue that can negatively affect the economic performance of cows, especially on pasture-based dairy farms. However, most genetic predictions (GP) of lameness have low accuracy because lameness data are often incomplete as data are collected voluntarily by farmers in countries such as Australia. The objective of this study was to find routinely measured traits that are correlated with lameness and use them in multivariate evaluation models to improve the accuracy of GP for lameness. We used health events and treatments associated with lameness recorded by Australian farmers from 2002 to early 2019. The lameness incidence rates in Holstein and Jersey cows were 3.3% and 4.6%, respectively. We analyzed the records of 36 other traits (milk production, conformation, fertility, and survival traits) to estimate genetic correlations with lameness. The estimated heritability ± standard error (and repeatability ± standard error) for lameness in both Holstein and Jersey breeds were very low: 0.007 ± 0.002 (and 0.029 ± 0.002) and 0.005 ± 0.003 (and 0.027 ± 0.006), respectively, in univariate sire models. For the GP models, we tested including measurements of overall type to prediction models for Holsteins, stature and body length for Jersey, and milk yield and fertility traits for both breeds. The average accuracy of GP, calculated from prediction error variances, were 0.38 and 0.24 for Holstein and Jersey sires, respectively, when estimated using univariate sire models and both increased to 0.43 using multivariate sire models. In conclusion, we found that the accuracy of GP for lameness could be improved by including genetically correlated traits in a multivariate model. However, to further improve the accuracy of predictions of lameness, precise identification and recording incidences of hoof or leg disorder, or large-scale recording of locomotion and claw scores by trained personnel should be considered.