cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Levels of ionotropic glutamate and muscarinic receptors in three animal models of schizophrenia
Creators: name: Dean, Brian
name: Boer, Simone
name: Scarr, Elizabeth
name: Um, Jung Yoon
name: Udawela, Madhara
name: van den Boom, Tom
name: Reinieren, Ivo
name: Cilia, Jackie
name: Hill, Mark
name: Bradford, Andrea
name: Jones, Declan N C
name: Gartlon, Jane
Publisher: name: Swinburne
Year: 2024

description: There are well validated rodent paradigms of schizophrenia which are based on environmental manipulation (e.g. altered rearing conditions) or drug challenges. These manipulations induce behavioural changes in rodents that are thought to involve neuronal circuitry similar to the ones that are affected by the pathophysiology of the disorder. This study has investigated whether three such rodent paradigms (isolation rearing, neonatal PCP treatment or sub-chronic PCP treatment) are associated with changes in muscarinic receptors (CHRMs) or ionotropic glutamate receptors, some of which have been reported to be altered in the CNS of subjects with schizophrenia. [3H]pirenzepine (CHRM1),[3H]4DAMP (CHRM1/CHRM3), [3H]MK801 (NMDA receptors) and [ 3H]kainate (kainate receptors; KAR) binding were measured using in situ radioligand binding and autoradiography. Isolation rearing caused widespread decreases in [3H]4DAMP (p = 0.01) and [3H]kainate binding (p = 0.03). Neonatal PCP caused widespread increases in [3H]4DAMP binding (p <0.0001), whereas sub-chronic PCP treatment caused widespread decreases in the binding of that radioligand (p < 0.002) and widespread increases in [3H]MK801 binding (p < 0.0001). There were no changes in [3H]pirenzepine binding to CHRM1 receptors in any paradigm or no significant within region changes in the binding of any radioligand. In conclusion, in the absence of any changes in CHRM1 receptors, our [3H]4DAMP and the binding of [3H]MK801 data would suggest that different rodent paradigms cause variable changes in levels of CHRM3 and KAR in the rat CNS. Our data raises the possibility that such changes may, in part, modulate the behavioural differences that have been observed after isolation rearing, neonatal PCP treatment or sub-chronic PCP treatment.
Entry-to-Practice PharmD Program : Outpatient Practicums Handbook for Students and Practice Educators : Introductory and Advanced Pharmacy Practice Experiences (IPPE, APPE) – Outpatient, May 2018-2019
Creators: name: Lau, Gilly
name: Fang, Kayla
name: Dhaliwal, Neelam
name: Tchen, Paulo
Publisher: name: The University of British Columbia
Year: 2019

Abstract
Effects of communication training and contracting on disturbed marital relationships.
Creators: name: Stein, Steven J.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1978
Subjects: subject: Education, Guidance and Counseling.

description: This study investigated the effects of the two kinds of marital therapy programs on couples volunteering to improve their relationships. Two groups of couples participated in the Minnesota Couples Communication Program. One of these groups was posttested immediately after treatment while the other was posttested six weeks following treatment. A third group of couples played the Family Contract Game which was adapted for couples in the present study. Finally, there was a waiting list Control group who received the same pretest and posttest procedures as the previous groups. All groups self-monitored throughout the 5 weeks during which treatment occurred as well as for 6 weeks following the termination of the treatment phase. A series of self-report, self-monitoring, and behavioural measures of all spouses were taken at the beginning and end of the treatment program. Couples in the Communications Program tested immediately following treatment decreased in the number of positive responses they gave while discussing problem issues, reported being less happy with their relationship, but spent more time together. Communications couples tested 6 weeks after treatment gave fewer negative responses when discussing a problem issue, received fewer pleasing and displeasing behaviours from their spouse, and spent more time together. Contracting couples gave more positive responses when discussing a problem issue, increased their reported happiness with their relationship and decreased in the number of displeasing behaviours received. Control couples decreased in their reported happiness with their relationship during the self-monitoring period, and at the time of posttesting reported spending more time together; they also requested fewer changes of their spouse in problem areas, and requested less change in the number of activities they wanted to do with their spouse. These results suggest that, at best, Communications Skills training has minimal behavioural change consequences for marital relationships, and at most, such training can result in iatrogenic effects. The Contracting procedure was the most effective in producing behavioural and subjective changes in marital relationships and would seem to hold the greatest promise for understanding and treating certain disturbed marital relations.
Oxidation of isobutene over selenium dioxide modified copper oxide catalysts.
Creators: name: Yao, Kuang-Chen.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1966
Subjects: subject: Engineering, Chemical.

description: The effect of various amounts of SeO2, a p-type impurity, in modifying the selectivity of the copper oxide catalysts for methacrolein production, in the catalytic oxidation of isobutylene was investigated, at different feed ratios and several temperatures up to 425°C, in an isothermal integral flow reactor. The reaction products were analyzed quantitatively by gas chromatography. It has been found that there is an optimal amount of SeO2 required at each operating condition to enhance the selectivity of the catalyst. The experimental results are explained with the electron theory of catalysis on semiconductors and a reaction mechanism proposed. It has been postulated that the rate determining step in the partial oxidation of isobutene to methacrolein is a p-type and its further oxidation to water and CO2 is an n-type, under the operating, conditions.
Synthesis of Carbon Dots from Low-Cost Precursors and Study of Concentration-Dependent Emission Properties
Creators: name: Özyurt, Derya
Publisher: name: Swinburne
Year: 2024

description: Quantum Dots are nano-sized materials with interesting emission properties, which can be used in bio-imaging, sensing and anticounterfeiting applications. However, these materials are expensive to synthesize, and toxic in environmental and bio-applications. Carbon dots with similar optical properties are non-toxic materials which can replace quantum dots in various applications. In this thesis, the synthesis and characterization of nitrogen-doped carbon dots from low-cost materials such as citric acid, humic acid and brown coal precursors were studied. Herein, we showed that the emission properties of citric acid-based carbon dots could be controlled by simply varying the concentration and aggregation of the particles, resulting in emission red-shift from blue to greenish yellow. The emission of citric acid-based carbon dots was further studied in polymer matrix to evaluate potential solid-state applications.
title: Lesiones quísticas retroperitoneales: una aproximación diagnóstica mediante correlación clínico-radiológica.
Creators: name: Batista Martin, Daniel
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen
subject: CT
subject: Cysts

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Describir las características radiológicas y clínicas más relevantes de las lesiones quísticas...
Building the capacity of family day care educators to promote children's social and emotional wellbeing: An exploratory cluster randomised controlled trial
Creators: name: Davis, Elise
name: Williamson, Lara
name: MacKinnon, Andrew
name: Cook, Kay
name: Waters, Elizabeth
name: Herrman, Helen
name: Sims, Margaret
name: Mihalopoulos, Cathrine
name: Harrison, Linda
name: Marshall, Bernard
Publisher: name: Swinburne
Year: 2024

description: Background: Childhood mental health problems are highly prevalent, experienced by one in five children living in socioeconomically disadvantaged families. Although childcare settings, including family day care are ideal to promote children's social and emotional wellbeing at a population level in a sustainable way, family day care educators receive limited training in promoting children's mental health. This study is an exploratory wait-list control cluster randomised controlled trial to test the appropriateness, acceptability, cost, and effectiveness of "Thrive," an intervention program to build the capacity of family day care educators to promote children's social and emotional wellbeing. Thrive aims to increase educators' knowledge, confidence and skills in promoting children's social and emotional wellbeing. [Abstract truncated]
title: Enfermedad fistulosa perianal en Resonancia Magnética
Creators: name: Corral de la Calle, Miguel Ángel
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen
subject: Anatomy
subject: Colon
subject: MR
subject: Education
subject: Abscess
subject: Fistula
subject: Infection

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Recordar los datos epidemiológicos y clínicos más relevantes de la enfermedad fistulosa perianal. Dominar la anatomía radiológica de la región perianal,
y especialmente la que ofrecen las imágenes obtenidas por RM,
con esquemas anatómicos....
Biodiversity of plants: Broad-scale patterns and mechanisms
Creators: name: Francis, Anthony P
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Biology, Botany.
subject: Biology, Ecology.

description: One of the most obvious patterns in ecology is the geographic variation in species richness over broad spatial scales. However, despite observations of these patterns of richness for two centuries, mechanisms for the patterns remain controversial. This thesis is a study of the broad-scale biodiversity patterns of plants and the potential mechanisms behind those patterns. Richness-climate relationships often account for >80% of the spatial variance in richness. However, it has been suggested that richness-climate relationships differ significantly among geographic regions, and that there is no globally consistent relationship. Since there is little point in arguing about mechanisms before the patterns they predict have been documented, I investigated the global patterns of species and family richness of angiosperms in relation to climate. One hypothesized mechanism that predicts strong and consistent richness-climate patterns is the Physiological Tolerances hypothesis. This hypothesis predicts that the number of species found in a given location is a function of the number that can tolerate the climatic conditions in that place. Using global angiosperm family richness distributions and climatic data to estimate the climatic tolerances of plant families, I examined the relationships of potential family richness patterns to both climatic gradients and observed patterns of family richness. Observed family richness was not strongly related to potential family richness. However, both richness and potential richness were related to climate, but in different ways. Potential family richness necessarily sets an upper limit on observed richness levels, but observed richness did not generally reach that limit. In other words, there are generally many more species that can tolerate the climate in a particular area than actually occur there. A second hypothetical mechanism predicting strong consistent richness-climate patterns, the Energy-Diversity or Species-Energy hypothesis, suggests that for a species to persist in an area, there must be sufficient energy available in that area to support enough individuals of that species to maintain a viable population. Thus species richness will depend upon the number of individuals, which in turn depends upon energy availability. Using tree counts from 15 forest sites along a latitudinal gradient running from James Bay, Canada to Costa Rica, I tested whether a series of direct correlative links existed from climate to tree density to tree species richness. Despite a positive (but not statistically significant) correlation between AET and richness, the tree density per site was negatively correlated with energy. (Abstract shortened by UMI.)
title: Cortocircuito cardíaco. Tipos y utilidad de la RM
Creators: name: Nieto Baltar, Beatriz
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: MR
subject: Cardiac

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
1.
Conocer las posibles causas de de shunt,
intra y extracardíaco. 2.
Mostrar la patología asociada. 3.
Valorar la repercusión funcional y posibles...
Blauer Engel "Austauschkatalysatoren"
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2014
Subjects: subject: Abgaskatalysator
subject: Feinstaub
subject: Feinstaubabscheidung
subject: Luft
subject: Air
subject: Verkehr
subject: Transport

description: Ein Katalysator ist heutzutage serienmäßg eingebaut, damit Autoabgase weniger Schadstoffe enthalten. Ist er defekt, heißt es Augen auf beim Nachkauf. Denn viele Exemplare, die derzeit im Handel verfügbar sind, reinigen erschreckend schlecht und verlieren schnell ihre Wirksamkeit. Doch ab jetzt können Sie auf qualitätsgeprüfte Austauschkatalysatoren mit dem „Blauen Engel“ zurückgreifen. Im Februar 2014 wurden die ersten Produkte mit dem Umweltzeichen ausgezeichnet.Der Blauer Engel für Austauschkatalysatoren umfasst auch Anforderungen zur Vermeidung gesundheitsschädlicher Wirkungen aus künstlichen Mineralfasern, die in den Lagermatten der Katalysatoren eingesetzt werden.
title: Influence of Granulocyte-Macrophage Colony-Stimulating Factor or Influenza Vaccination on HLA-DR, Infection and Delirium Days in Immunosuppressed Surgical Patients
title: Double Blind, Randomised Controlled Trial
titleType: Subtitle
Creators: name: Spies, Claudia
name: Luetz, Alawi
name: Lachmann, Gunnar
name: Renius, Markus
name: Haefen, Clarissa Von
name: Wernecke, Klaus-Dieter
name: Bahra, Marcus
name: Schiemann, Alexander
name: Paupers, Marco
name: Meisel, Christian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Purpose Surgical patients are at high risk for developing infectious complications and postoperative delirium. Prolonged infections and delirium result in worse outcome. Granulocyte-macrophage colony-stimulating factor (GM- CSF) and influenza vaccination are known to increase HLA-DR on monocytes and improve immune reactivity. This study aimed to investigate whether GM-CSF or vaccination reverses monocyte deactivation. Secondary aims were whether it decreases infection and delirium days after esophageal or pancreatic resection over time. Methods In this prospective, randomized, placebo-controlled, double-blind, double dummy trial setting on an interdisciplinary ICU of a university hospital 61 patients with immunosuppression (monocytic HLA-DR [mHLA-DR] <10,000 monoclonal antibodies [mAb] per cell) on the first day after esophageal or pancreatic resection were treated with either GM-CSF (250 μg/m2/d), influenza vaccination (Mutagrip 0.5 ml/d) or placebo for a maximum of 3 consecutive days if mHLA-DR remained below 10,000 mAb per cell. HLA-DR on monocytes was measured daily until day 5 after surgery. Infections and delirium were followed up for 9 days after surgery. Primary outcome was HLA-DR on monocytes, and secondary outcomes were duration of infection and delirium. Results mHLA-DR was significantly increased compared to placebo (p < 0.001) and influenza vaccination (p < 0.001) on the second postoperative day. Compared with placebo, GM-CSF-treated patients revealed shorter duration of infection (p < 0.001); the duration of delirium was increased after vaccination (p = 0.003). Conclusion Treatment with GM-CSF in patients with postoperative immune suppression was safe and effective in restoring monocytic immune competence. Furthermore, therapy with GM-CSF reduced duration of infection in immune compromised patients. However, influenza vaccination increased duration of delirium after major surgery.
Referenzprozessmodelle: Bestandsaufnahme, Synopse und Entwicklungspotentiale
Creators: name: Konrad, Thomas
name: Puchan, Joerg
name: Gann, Thomas
Publisher: name: e-Journal of Practical Business Research
Year: 2012
Subjects: managementScience

description: e-Journal of Practical Business Research, Business Process Benchmarking - Band I Grundlagen, S. 1-40
Prozesskennzahlen
Creators: name: Seifert, Lena
name: Lindner, Andreas
name: Vo, Hoang
name: Drexler, Magdalena
name: Puchan, Joerg
name: Gann, Thomas
Publisher: name: e-Journal of Practical Business Research
Year: 2012
Subjects: managementScience

description: e-Journal of Practical Business Research, Business Process Benchmarking - Band I Grundlagen, S. 1-33
An ontology of trash: The disposable and its problematic nature
Creators: name: Kennedy, Greg
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Philosophy.

description: The study investigates disposability as a uniquely modern ontological mode of existence. A disposable is something a priori wasted, a phenomenon whose presence in the world presupposes its absence. Consequently, from a phenomenological perspective, the essence of a disposable includes its non-existence, or more strongly, its essence excludes its more than instantaneous existence. Trash is taken as an ontological category that extends over all disposable beings. An historical interpretation is ventured that traces the current predominance of this category to the original metaphysical denigration of the sensuous human body. Only through the sensitive body do we experience the materiality, impenetrability and integrity of physical things. As technology and metaphysics continue to disengage our sensual capacities for perception, our understanding of physical things becomes increasingly tenuous and abstract. In the absence of tactile commerce with resilient and resistant things, we fail to encounter their physical, independent existence. Their being thus seems ever more thoroughly to depend on how we rationally conceive, determine and design them. However, the undeniable evidence of trash, and the threat it poses to our own continued existence demonstrate a fatal flaw in our exclusively rationalized relation with the physical world. If we desire to avoid the "throw-away society's" dangerous excesses, we must secure metaphysics and technology to a sensitive, physical participation with the world that takes care to preserve the being of things, by the generosity of which our own being is preserved.
The identification of dust heating mechanisms in nearby galaxies using Herschel 160/250 and 250/350μm surface brightness ratios
Creators: name: Bendo, G. J.
name: Baes, M.
name: Bianchi, S.
name: Boquien, M.
name: Boselli, A.
name: Cooray, A.
name: Cortese, Luca
name: De Looze, I.
name: di Serego Alighieri, S.
name: Fritz, J.
name: Gentile, G.
name: Hughes, T. M.
name: Lu, N.
name: Pappalardo, C.
name: Smith, M. W L
name: Spinoglio, L.
name: Viaene, S.
name: Vlahakis, C.
Publisher: name: Swinburne
Year: 2024

description: We examined variations in the 160/250 and 250/350 µm surface brightness ratios within 24 nearby (<30 Mpc) face-on spiral galaxies observed with the Herschel Space Observatory to identify the heating mechanisms for dust emitting at these wavelengths. The analysis consisted of both qualitative and quantitative comparisons of the 160/250 and 250/350 µm ratios to Hα and 24 µm emission, which trace the light from star-forming regions, and 3.6 µm emission, which traces the light from the older stellar populations of the galaxies. We find broad variations in the heating mechanisms for the dust. In one subset of galaxies, we found evidence that emission at =160 µm (and in rare cases potentially at =350 µm) originates from dust heated by star-forming regions. In another subset, we found that the emission at =250 µm (and sometimes at =160 µm) originates from dust heated by the older stellar population. In the rest of the sample, either the results are indeterminate or both of these stellar populations may contribute equally to the global dust heating. The observed variations in dust heating mechanisms do not necessarily match what has been predicted by dust emission and radiative transfer models, which could lead to overestimated dust temperatures, underestimated dust masses, false detections of variability in dust emissivity, and inaccurate star formation rate measurements.
Compressive Behaviours of Origami-based Structures
Creators: name: Qiang, Wei
Publisher: name: Swinburne
Year: 2024

description: Origami techniques enable the transformation of a two-dimensional (2D) sheet into a three-dimensional (3D) structure. Since the 1970s, this folding technique has been utilized not only for aesthetic purposes but also for engineering applications, particularly in designing energy absorption and impact protection devices. This dissertation examines the compressive behavior and energy absorption performance of origami-based structures using analytical, numerical, and experimental methods. The study investigates origami structures made of composite and metallic materials with different patterns and subjected to various loading conditions. The results of this work are compared to provide valuable insights into the design of origami-based energy absorbers.
Do associations between objectively-assessed physical activity and neighbourhood environment attributes vary by time of the day and day of the week? IPEN adult study
Creators: name: Cerin, Ester
name: Mitáš, Josef
name: Cain, Kelli L.
name: Conway, Terry L.
name: Adams, Marc A.
name: Schofield, Grant
name: Sarmiento, Olga L.
name: Reis, Rodrigo Siqueira
name: Schipperijn, Jasper
name: Davey, Rachel
name: Salvo, Deborah
name: Orzanco-Garralda, Rosario
name: Macfarlane, Duncan J.
name: De Bourdeaudhuij, Ilse
name: Owen, Neville
name: Sallis, James F.
name: Van Dyck, Delfien
Publisher: name: Swinburne
Year: 2024

description: Background: To more accurately quantify the potential impact of the neighbourhood environment on adults' physical activity (PA), it is important to compare environment-PA associations between periods of the day or week when adults are more versus less likely to be in their neighbourhood and utilise its PA resources. We examined whether, among adults from 10 countries, associations between objectively-assessed neighbourhood environment attributes and moderate-to-vigorous physical activity (MVPA) varied by time of the day and day of the week. The secondary aim was to examine whether such associations varied by employment status, gender and city. Methods: This cross-sectional study included 6,712 adults from 14 cities across 10 countries with ≥1 day of valid accelerometer-assessed MVPA and complete information on socio-demographic and objectively-assessed environmental characteristics within 0.5 and 1 km street-network buffers around the home. Accelerometer measures (MVPA min/h) were created for six time periods from early morning until late evening/night, for weekdays and weekend days separately. Associations were estimated using generalized additive mixed models. Results: Time of the day, day of week, gender and employment status were significant moderators of environment-MVPA associations. Land use mix was positively associated with MVPA in women who were employed and in men irrespective of their employment status. The positive associations between MVPA and net residential density, intersection density and land use mix were stronger in the mornings of weekdays and the afternoon/evening periods of both weekdays and weekend days. Associations between number of parks and MVPA were stronger in the mornings and afternoon/evenings irrespective of day of the week. Public transport density showed consistent positive associations with MVPA during weekends, while stronger effects on weekdays were observed in the morning and early evenings. Conclusions: This study suggests that space and time constraints in adults' daily activities are important factors that determine the impact of neighbourhood attributes on PA. Consideration of time-specific associations is important to better characterise the magnitude of the effects of the neighbourhood environment on PA. Future research will need to examine the contribution of built environment characteristics of areas surrounding other types of daily life centres (e.g., workplaces) to explaining adults' PA at specific times of the day.
A novel framework for designing with vulnerable people and sensitive topics: Reflecting on a participatory design case study in the Australian adolescent oncofertility setting
Creators: name: Misiakos, Georgios Ioannis
Publisher: name: Swinburne
Year: 2024

description: There is a significant knowledge gap concerning vulnerable people in design research for products and services that feature sensitive topics, potentially resulting in significant unmet needs for this population. This thesis explores designing with vulnerable people and sensitive topics, through an in-depth examination of a case study in the Australian adolescent oncofertility setting. The findings suggest that understanding the intersection of vulnerability and sensitive topics is paramount to setting the appropriate scope, focus and structure for a design project. The proposed novel framework can guide for participatory designers, align multidisciplinary teams, and explore how complex social issues intersect.
Magnetic subfabrics of the Whistle Offset dyke and embayment, Sudbury Impact Structure, Sudbury, Ontario
Creators: name: Giroux, Laura Allison
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Geology.

description: Quartz-diorite Offset dykes from the 1850 Ma Sudbury Impact Structure stem from the Sudbury Igneous Complex (SIC) and extend into the footwall rocks in radial and concentric patterns with respect to the SIC. The dykes formed by emplacement of magma derived from the impact melt body into radial and concentric fractures generated in the country rock by the hypervelocity meteorite impact. The NE-striking Whistle Offset dyke extends from the northeast corner of the SIC, and is connected to the SIC by the Whistle embayment structure. A suite of oriented specimens was collected from 20 sites in the Whistle Offset dyke and the embayment, in order to determine the emplacement flow pattern within the dyke, the embayment, and the hosted massive sulfide deposits. The emplacement flow pattern was studied by using magnetic anisotropy measurements in order to infer the petrofabrics, and the subfabrics, defined by different mineral populations. The magnetic anisotropy methods included the anisotropy of magnetic susceptibility (AMS), the anisotropy of anhysteretic remanence (AAR) and the anisotropy of partial anhysteretic remanence (ApAR). The complex magnetic mineralogy of the sample suite was examined using measurements of partial anhysteretic remanence (PAR) acquisition, alternating-field demagnetization and thermal demagnetization, in addition to petrographic and scanning electron microscope (SEM) studies. The subfabrics which are interpreted to record the flow pattern in the Whistle Offset dyke, are defined by low coercivity coarse-grained magnetite, interpreted to be of primary igneous origin. The fabrics are suggestive of lateral (horizontal) injection of the magma and subsequent sinking of molten massive sulfide bodies through the still unsolidified dyke. Sinking of the massive sulfides is recorded by moderately plunging to vertical magnetic lineations. Steeply plunging lineations elsewhere in the Offset dykes may also indicate the presence of sunken massive sulfides in the subsurface.
Discovery of Extreme [O III]+Hβ Emitting Galaxies Tracing an Overdensity at z ∼ 3.5 in CDF-South
Creators: name: Forrest, Ben
name: Tran, Kim Vy H
name: Broussard, Adam
name: Allen, Rebecca
name: Apfel, Miranda
name: Cowley, Michael J.
name: Glazebrook, Karl
name: Kacprzak, Glenn
name: Labbe, Ivo
name: Nanayakkara, Themiya
name: Papovich, Casey
name: Quadri, Ryan F.
name: Spitler, Lee R.
name: Straatman, Caroline M S
name: Tomczak, Adam
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: Using deep multi-wavelength photometry of galaxies from zfourge, we group galaxies at 2.5 < z < 4.0 by the shape of their spectral energy distributions (SEDs). We identify a population of galaxies with excess emission in the K s-band, which corresponds to [O III]+Hβ emission at 2.95 < z < 3.65. This population includes 78% of the bluest galaxies with UV slopes steeper than β = -2. We de-redshift and scale this photometry to build two composite SEDs, enabling us to measure equivalent widths of these extreme [O III]+Hβ emission line galaxies (EELGs) at z ∼ 3.5. We identify 60 galaxies that comprise a composite SED with a [O III]+Hβ rest-frame equivalent width of 803 ±228 Å and another 218 galaxies in a composite SED with an equivalent width of 230 ±90 Å. These EELGs are analogous to the "green peas" found in the SDSS and are thought to be undergoing their first burst of star formation due to their blue colors (β < -1.6), young ages (log(age yr-1) ∼ 7.2), and low dust attenuation values. Their strong nebular emission lines and compact sizes (typically ∼1.4 kpc) are consistent with the properties of the star-forming galaxies possibly responsible for reionizing the universe at z > 6. Many of the EELGs also exhibit Lyα emission. Additionally, we find that many of these sources are clustered in an overdensity in the Chandra Deep Field South, with five spectroscopically confirmed members at z = 3.474 ± 0.004. The spatial distribution and photometric redshifts of the zfourge population further confirm the overdensity highlighted by the EELGs.
Mixed covering arrays on graphs and tabu search algorithms
Creators: name: Zekaoui, Latifa
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Computer Science.

description: Covering arrays are combinatorial objects that have been successfully applied in the design of test suits for testing software, networks and circuits. Mixed covering arrays on graphs are new generalizations of both mixed covering arrays and covering arrays on graphs. In this thesis, we give new theoretical results and constructions for mixed covering arrays on graphs. First, we extend to the mixed case the work done by Meagher and Stevens [31], which uses graph homomorphisms for covering arrays on graphs. Second, we study covering arrays on special classes of graphs. In particular, we solve to optimality the case in which G is a tree, a cycle or a bipartite graph, as well as give results for wheels and cubic graphs. We also provide general graph operations that preserve the size of a balanced covering array. In the second part of the thesis, we do a complete experimental study of two tabu search algorithms for covering array construction. POT is a variation of the algorithm given by Stardom [40] while PAT is an implementation of the algorithm proposed by Nurmela [35]. We conclude that they provide effective methods for constructing covering arrays of moderate size. In particular, POT and PAT improve upper bounds for 18 sets of parameters for covering arrays.
UVUDF: UV Luminosity Functions at the Cosmic High Noon
Creators: name: Mehta, Vihang
name: Scarlata, Claudia
name: Rafelski, Marc
name: Gburek, Timothy
name: Teplitz, Harry I.
name: Alavi, Anahita
name: Boylan-Kolchin, Michael
name: Finkelstein, Steven
name: Gardner, Jonathan P.
name: Grogin, Norman
name: Koekemoer, Anton
name: Kurczynski, Peter
name: Siana, Brian
name: Codoreanu, Alexandru
name: De Mello, Duilia F.
name: Lee, Kyoung Soo
name: Soto, Emmaris
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 5101
subject: Astronomical sciences
classificationCode: 5109
subject: Space sciences

description: We present the rest-1500 Å UV luminosity functions (LF) for star-forming galaxies during the cosmic high noon- the peak of cosmic star formation rate at 1.5 < z < 3. We use deep NUV imaging data obtained as part of the Hubble Ultra-Violet Ultra Deep Field (UVUDF) program, along with existing deep optical and NIR coverage on the HUDF. We select F225W, F275W, and F336W dropout samples using the Lyman break technique, along with samples in the corresponding redshift ranges selected using photometric redshifts, and measure the rest-frame UV LF at z ∼ 1.7, 2.2, 3.0, respectively, using the modified maximum likelihood estimator. We perform simulations to quantify the survey and sample incompleteness for the UVUDF samples to correct the effective volume calculations for the LF. We select galaxies down to MUV = -15.9, -16.3, -16.8 and fit a faint-end slope of α = -1.20-0.13+0.10,-1.32+0.100.14, 1.39+0.08-0.12 at 1.4 < z < 1.9, 1.8 < z < 2.6, and 2.4 < z < 3.6, respectively. We compare the star formation properties of z ∼ 2 galaxies from these UV observations with results from Hα and UV +IR observations. We find a lack of high-SFR sources in the UV LF compared to the Hα and UV+IR, likely due to dusty SFGs not being properly accounted for by the generic IRX-β relation used to correct for dust. We compute a volume-averaged UV-to-Hα ratio by abundance matching the rest-frame UV LF and Hα LF. We find an increasing UV-to-Hα ratio toward low-mass galaxies (M∗ ≲ 5 ×109 M⊙). We conclude that this could be due to a larger contribution from starbursting galaxies compared to the high-mass end.
Investigations into genomic instability of endogenous and transfected hprt genes in mouse and human tumour cells.
Creators: name: Wilkinson, Diana.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Biology, Genetics.

description: A mouse model system was developed to sensitively detect mutagenic events arising spontaneously in mouse fibrosarcoma cells grown under in vitro or in vivo conditions. These cells were genetically manipulated to enhance their sensitivity as detectors of mutational events at the X-linked hprt (hypoxantine phosphoribosyltransferase) gene, a frequently used marker of genomic instability. A fibrosarcoma cell with three X-chromosomes and randomly distributed X-specific fragments was isolated from a male mouse. Initially, this cell line was resistant to mutation induction, presumably due to the presence of multiple hprt genes. Inactivation of all but one hprt gene resulted in a cell line with a heterozygous marker which was at least 1000 times more sensitive to detecting induced mutational events. Infection of this derived cell line with a selectable marker for neomycin resistance allowed recovery of cells which subsequently demonstrated that the tumour environment was capable of enhancing spontaneous in vitro mutation induction. A human lymphoblastoid cell line was also genetically manipulated to establish nine stable transfectants as models for the study of genomic instability. The endogenous X-linked hprt gene was mutated, presumably by a large deletion, and subsequently transfected with a human hprt minigene encoding for its own promoter and poly-adenosine signal. Transfectants were assessed for the stability of the transgene. Transfected clones demonstrated a 2 to 600 fold increase in spontaneous mutation rate at the transgene loci compared to the endogenous hprt locus. There was no evidence of mutator phenotype activation in any of the clones as judged by testing at another locus, the endogenous tk (thymidine kinase) gene. An inverse correlation was also noted between the number of the inserted sequences and the stability of gene expression, with single gene insertions being most stable and tandem insertions being the least stable.
Examining the Relationship Between Firefighter Injuries and Fatalities in the Built Environment : A case for reducing the risk to firefighters through adequate firefighting experience, working smoke alarms and sprinkler coverage in buildings
Creators: name: Zheng, Alex
name: Jiang, Andy
name: Rajabali, Fahra
name: Turcotte, Kate
name: Garis, Len
name: Pike, Ian, 1958-
Publisher: name: The University of British Columbia
Year: 2021

description: The purpose of this study is to describe firefighter injuries and deaths in structure-related fires and to investigate the underlying connection between building properties, including fire safety measures, and their effects on the risk to firefighters responding to a fire event. For the first time, comprehensive fire-related data across Canada is available in the form of the National Fire Information Database (NFID). Using this new dataset, in conjunction with a literature review and an Association of Worker Compensation Boards of Canada (AWCBC) dataset, this report explores the impact of building properties (e.g. construction material, height) and fire safety measures (e.g. sprinklers, fire alarms) on firefighter casualties. For the purposes of this report, casualties represent both injuries and deaths.
The Repetitions of Fast Radio Bursts
Creators: name: Kumar, Pravir
Publisher: name: Swinburne
Year: 2024

description: Fast radio bursts (FRBs) are brief, bright flashes of radio emission originating from sources billions of light-years away. While some FRB sources have been observed to emit multiple bursts, the question remains: Do all FRBs repeat? This thesis investigates the repeating nature and spectro-polarimetric properties of a population of FRB sources to understand the emission mechanism causing them. The study utilizes some of the world's most sensitive radio telescopes and employs a novel search technique to process the wideband data. The findings point towards a dynamic and highly magnetized environment that surrounds at least some repeating FRB sources.
Introduction to R
Creators: name: Sugis, Elena
name: Kolde, Raivo
name: Puura, Joonas
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Education
subject: 80604 Database Management
subject: FOS: Computer and information sciences
subject: 80702 Health Informatics
subject: FOS: Media and communications

description: This the study material for part Introduction to R of Data Literacy course.
Reduced Mass and Diversity of the Colonic Microbiome in Patients with Multiple Sclerosis and Their Improvement with Ketogenic Diet
Creators: name: Swidsinski, Alexander
name: Dörffel, Yvonne
name: Loening-Baucke, Vera
name: Gille, Christoph
name: Göktas, Önder
name: Reisshauer, Anne
name: Neuhaus, Jürgen
name: Weylandt, Karsten-Henrich
name: Guschin, Alexander
name: Bock, Markus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: FISH
subject: colonic microbiota
subject: multiple sclerosis
subject: biofermentation
subject: ketogenic diet
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background: Colonic microbiome is thought to be involved in auto-immune multiple sclerosis (MS). Interactions between diet and the colonic microbiome in MS are unknown. Methods: We compared the composition of the colonic microbiota quantitatively in 25 MS patients and 14 healthy controls.Fluorescence in situ hybridization (FISH) with 162 ribosomal RNA derived bacterial FISH probes was used. Ten of the MS patients received a ketogenic diet for 6 months. Changes in concentrations of 35 numerically substantial bacterial groups were monitored at baseline and at 2, 12, and 23/24 weeks. Results: No MS typical microbiome pattern was apparent.The total concentrations and diversity of substantial bacterial groups were reduced in MS patients (P < 0.001). Bacterial groups detected with EREC (mainly Roseburia), Bac303 (Bacteroides), and Fprau (Faecalibacterium prausnitzii) probes were diminished the most. The individual changes were multidirectional and inconsistent. The effects of a ketogenic diet were biphasic. In the short term, bacterial concentrations and diversity were further reduced. They started to recover at week 12 and exceeded significantly the baseline values after 23–24 weeks on the ketogenic diet. Conclusions: Colonic biofermentative function is markedly impaired in MS patients.The ketogenic diet normalized concentrations of the colonic microbiome after 6 months.
L'usage satisfaisant du langage et l'authenticité: Austin, Grice, Jacques et Ricoeur, la rencontre de deux traditions
Creators: name: Beaudoin, Simon
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Philosophy.
subject: Language, General.

description: Dans cette thèse, l'auteur met en lumière l'interdependance logique de deux projets philosophiques: celui d'une détermination des conditions de satisfaction de l'usage du langage et celui de l'élaboration d'un modèle d'authenticité qui prend en compte les avancées récentes dans le domaine de la philosophie du langage. Si la définition des conditions de l'authenticité permet de fonder et de préciser les conditions de l'usage satisfaisant du langage, ces dernières déterminent en retour concrètement l'idéal d'authenticité. Ainsi, pour déterminer comment l'être de langage que nous sommes peut actualiser ses possibilités les plus propres, nous ne pouvons faire abstraction d'une définition solide des conditions pragmatiques de l'usage satisfaisant du langage. Chacun des chapitres qui composent cette thèse contribue a tirer au clair les relations entre l'usage satisfaisant du langage et l'idéal d'authenticité. L'auteur prend d'abord pour point de départ des analyses concrètes de l'usage du langage. Ce sont alors les analyses de la philosophie du langage ordinaire de J. L. Austin qui sont mises a contribution. Mais pour définir l'ensemble des maximes qui doivent être considerées en tant que règles constitutives et normatives de l'usage satisfaisant du langage, l'auteur s'inspire des analyses de P. Grice et de F. Armengaud. Trois exigences fondamentales (veridicité, pertinence et clarté) sont ainsi définies et explicitées sous la forme de quinze maximes normatives. Celles-ci s'appliquent certes à l'usage du langage, mais aussi plus généralement à l'action. De là, l'auteur élabore un modèle d'authenticité qui peut à la fois intégrer et rendre compte des conditions de l'usage satisfaisant du langage. L'éthique téléologique et l'ontologie de l'ipséité sont alors mises a contribution. Mais pour faire le pont entre les conditions de l'authenticité et celles de l'usage satisfaisant du langage, l'auteur situe, au coeur de la quête d'authenticité, l'actualisation d'une compétence pragmatique essentielle. S'inspirant de l'approche pragmatique de F. Jacques puis de celle herméneutique de P. Ricoeur, l'auteur propose un modèle d'authenticité novateur ayant comme clef de voute la définition de cette compétence pragmatique essentielle. Ainsi s'établissent au passage un ensemble de rapports entre différents types de discours philosophiques et un dialogue fécond entre les auteurs qui les ont pratiqués.
Towards harmonisation of testing of nanomaterials for EU regulatory requirements on chemical safety - a proposal for further actions
Creators: name: Bleeker, Eric A.J.
name: Swart, Elmer
name: Braakhuis, Hedwig
name: Schwirn, Kathrin
Publisher: name: My University
Year: 2023
Subjects: Nanomaterialien

description: Over the recent years, EU chemicals legislation, guidance and test guidelines have been developed or adapted for nanomaterials to facilitate safe use of nanomaterials. This paper provides an overview of the information requirements across different EU regulatory areas. For each information requirement, a group of 22 experts identified potential needs for further action to accommodate guidance and test guidelines to nanomaterials. Eleven different needs for action were identified, capturing twenty-two information requirements that are specific to nanomaterials and relevant to multiple regulatory areas. These were further reduced to three overarching issues: 1) resolve issues around nanomaterial dispersion stability and dosing in toxicity testing, in particular for human health endpoints, 2) further develop tests or guidance on degradation and transformation of organic nanomaterials or nanomaterials with organic components, and 3) further develop tests and guidance to measure (a)cellular reactivity of nanomaterials. Efforts towards addressing these issues will result in better fit-for-purpose test methods for (EU) regulatory compliance. Moreover, it secures validity of hazard and risk assessments of nanomaterials. The results of the study accentuate the need for a structural process of identification of information needs and knowledge generation, preferably as part of risk governance and closely connected to technological innovation policy. © 2023 The Authors
Probing cosmological growth and expansion with the peculiar velocity field
Creators: name: Turner, Ryan James
Publisher: name: Swinburne
Year: 2024

description: This thesis studies how the velocities of galaxies in the nearby Universe can be used to make optimal measurements of the current expansion rate of the Universe and to accurately measure how structure grows in the Universe, under the influence of gravity. To do so, this thesis develops novel methods of measuring the cross-correlation between the peculiar velocities of galaxies and their positions in the sky, reducing the measurement error in key cosmological parameters. Different models of gravity will predict different behaviours in the rates of expansion and growth, this thesis provides an avenue for exploring these alternative theories.
title: Physicians' occupational stress, depressive symptoms and work ability in relation to their working environment
title: a cross-sectional study of differences among medical residents with various specialties working in German hospitals
titleType: Subtitle
Creators: name: Bernburg, Monika
name: Vitzthum, Karin
name: Groneberg, David A.
name: Mache, Stefanie
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Objectives This study aimed to analyse and compare differences in occupational stress, depressive symptoms, work ability and working environment among residents working in various medical specialties. Methods 435 German hospital residents in medical training working in 6 different medical specialties participated in a cross-sectional survey study. Physicians were asked about their working conditions and aspects of mental health and work ability. The Copenhagen Psychosocial Questionnaire, the Work Ability Index, the ICD-10 Symptom Rating and the Perceived Stress Questionnaire were used to measure working conditions, mental health and work ability. Results Results show that up to 17% of the physicians reported high levels of occupational distress and 9% reported high levels of depressive symptoms. 11% of the hospital physicians scored low in work ability. Significant differences between medical specialties were demonstrated for occupational distress, depressive symptoms, work ability, job demands and job resources. Surgeons showed consistently the highest levels of perceived distress but also the highest levels of work ability and lowest scores for depression. Depressive symptoms were rated with the highest levels by anaesthesiologists. Significant associations between physicians’ working conditions, occupational distress and mental health- related aspects are illustrated. Conclusions Study results demonstrated significant differences in specific job stressors, demands and resources. Relevant relations between work factors and physicians' health and work ability are discussed. These findings should be reinvestigated in further studies, especially with a longitudinal study design. This work suggests that to ensure physicians' health, hospital management should plan and implement suitable mental health promotion strategies. In addition, operational efficiency through resource planning optimisation and work process improvements should be focused by hospital management