cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(101769) Albion Charles Osmond
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Isobutylmethylxanthine fails to stimulate chloride secretion in cystic fibrosis airway epithelia.
Creators: name: Lazarowski, E.
name: Grubb, B.
name: Boucher, R.
name: Knowles, M.
Publisher: name: American Lung Association
Year: 1993

description: It has been proposed that a combination of an activated adenylyl cyclase and a high concentration of a phosphodiesterase inhibitor (isobutylmethylxanthine [IBMX], 5 mM) stimulates Cl- secretion mediated by the heterologously expressed cystic fibrosis transmembrane regulator protein carrying the most common cystic fibrosis (CF) mutation (delta F508). We tested whether Cl- secretion could be stimulated by this protocol in vitro and in vivo in CF airway epithelia expressing endogenous delta F508 CFTR protein. In cultured airway preparations, forskolin (a direct adenylyl cyclase activator) stimulated Cl- secretion in amiloride-pretreated normal (delta Isc = 7.1 +/- 1.7 microA.cm-2) but not CF tissues (delta Isc = -02 +/- 0.1 microA.cm-2). Unexpectedly, IBMX partially inhibited the forskolin-induced Cl- secretion in normal tissues; IBMX addition had no effect on CF tissues. Direct measurements of cell cAMP concentrations revealed that 0.1 mM IBMX and forskolin produced the maximum levels of cell cAMP levels attainable with this drug combination, and 5 mM IBMX was without further effect. The combination of forskolin (10(-5) M) and isoproterenol, an adenylyl cyclase activator (10(-5) M), produced approximately 3 times higher levels of cAMP than forskolin/IBMX but also did not induce Cl- secretion in CF tissues.
Superconductivity in Ca-doped graphene
Creators: name: Chapman, J.
name: Su, Y.
name: Howard, C. A.
name: Kundys, D.
name: Grigorenko, A.
name: Guinea, F.
name: Geim, A. K.
name: Grigorieva, I. V.
name: Nair, R. R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Graphene, a zero-gap semimetal, can be transformed into a metallic, semiconducting or insulating state by either physical or chemical modification. Superconductivity is conspicuously missing among these states despite considerable experimental efforts as well as many theoretical proposals. Here, we report superconductivity in calcium-decorated graphene achieved by intercalation of graphene laminates that consist of well separated and electronically decoupled graphene crystals. In contrast to intercalated graphite, we find that Ca is the only dopant that induces superconductivity in graphene laminates above 1.8 K among intercalants used in our experiments such as potassium, caesium and lithium. Ca-decorated graphene becomes superconducting at ~ 6 K and the transition temperature is found to be strongly dependent on the confinement of the Ca layer and the induced charge carrier concentration. In addition to the first evidence for superconducting graphene, our work shows a possibility of inducing and studying superconductivity in other 2D materials using their laminates.
ATF2 Proposal, Vol. 2.
Creators: name: Grishanov, B.
name: Logachev, P.
name: Podgorny, F.
name: Telnov, V.
name: Angal-Kalinin, D.
name: Jones, J.
name: Kalinin, A.
name: Napoly, O.
name: Payet, J.
name: Braun, H.-H.
name: Schulte, D.
name: Zimmermann, F.
name: Appleby, R.
name: Barlow, R.
name: Bailey, I.
name: Jenner, L.
name: Jones, R.
name: Kourevlev, G.
name: Elsen, E.
name: Vogel, V.
name: Walker, N.
name: Solyak, N.
name: Wendt, M.
name: Takahashi, T.
name: Gao, J.
name: Liu, W.
name: Pei, G.-X.
name: Wang, J.-Q.
name: Delerue, N.
name: Dixit, S.
name: Howell, D.
name: Reichhold, A.
name: Urner, D.
name: Bosco, A.
name: Agapov, I.
name: Blair, G. A.
name: Boorman, G.
name: Carter, J.
name: Driouichi, C.
name: Araki, S.
name: Hayano, H.
name: Higashi, Y.
name: Honda, Y.
name: Kanazawa, K.
name: Kubo, K.
name: Kume, T.
name: Kuriki, M.
name: Kuroda, S.
name: Masuzawa, M.
name: Naito, T.
name: Okugi, T.
name: Sugahara, R.
name: Tauchi, T.
name: Teronuma, N.
name: Toge, N.
name: Urakawa, J.
name: Yamaoka, H.
name: Yokoya, K.
name: Iwashita, Y.
name: Mihara, T.
name: Pons, M. A.
name: Bambade, P.
name: Dadoun, O.
name: DESY
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2006

description: DESY (2006).
Poiseuille flow past a nanoscale cylinder in a slit channel: Lubrication theory versus molecular dynamics analysis
Creators: name: Rahmani, Amir M.
name: Shao, Yang
name: Jupiterwala, Mehlam
name: Colosqui, Carlos E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Plane Poiseuille flow past a nanoscale cylinder that is arbitrarily confined (i.e., symmetrically or asymmetrically confined) in a slit channel is studied via hydrodynamic lubrication theory and molecular dynamics simulations, considering cases where the cylinder remains static or undergoes thermal motion. Lubrication theory predictions for the drag force and volumetric flow rate are in close agreement with molecular dynamics simulations of flows having molecularly thin lubrication gaps, despite the presence of significant structural forces induced by the crystalline structure of the modeled solid. While the maximum drag force is observed in symmetric confinement, i.e., when the cylinder is equidistant from both channel walls, the drag decays significantly as the cylinder moves away from the channel centerline and approaches a wall. Hence, significant reductions in the mean drag force on the cylinder and hydraulic resistance of the channel can be observed when thermal motion induces random off-center displacements. Analytical expressions and numerical results in this work provide useful insights into the hydrodynamics of colloidal solids and macromolecules in confinement.
title: Rare forms of Ewings sarcoma: A pictorial review
Creators: name: Mohan, Neha
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Oncology
subject: Musculoskeletal bone
subject: Digital radiography
subject: CT
subject: MR
subject: Education
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Ewing sarcoma is a well-known paediatric bone tumour. In fact, it is the second most common primary malignant bone tumour in children and adolescents after osteosarcoma [1]. But beware, not all of them have straight forward typical manifestations, a...
Nucleotide regulation of goblet cells in human airway epithelial explants: normal exocytosis in cystic fibrosis.
Creators: name: Boucher, R.C.
name: Van Scott, M.
name: Davis, C.W.
name: Egan, T.
name: Dowell, M.L.
name: Lethem, M.I.
name: Yankaskas, J.R.
Publisher: name: American Lung Association
Year: 1993

description: The regulation of mucin secretion by airway goblet cells is poorly understood and the receptor-based regulatory mechanisms have not been described in human airways. In the present study, we report that extracellular triphosphate nucleotides regulate the rate of granule release from goblet cells in both normal and cystic fibrosis (CF) airway epithelial explants. Explants isolated from nasal and tracheobronchial tissues were mounted in perfusion chambers and the secretory activity was assessed by videomicroscopic determination of degranulation in single goblet cells and by ELISA determination of mucins secreted into the mucosal perfusate. Baseline degranulation was measured at 0.05 degranulation events (DE)/min. In normal goblet cells, mucosal ATP (10(-4) M, n = 17) induced a biphasic secretory response comprising 29.1 +/- 4.9 DE during the first 5 min, with an initial rate of 118.2 +/- 10.2 DE/min. Mucosal UTP (10(-4) M, n = 9) induced a similar response to ATP (initial rate: 89.2 +/- 23.9 DE/min, 17.9 +/- 5.1 DE in 5 min), but mucosal 2-MeSATP was not an effective agonist (initial rate: 1.5 +/- 1.4 DE/min, 2.3 +/- 0.5 DE in 5 min). Determination of mucins by ELISA confirmed that both ATP and UTP induced similar secretory responses but that 2-MeSATP was not effective. In CF explants, mucosal UTP (10(-4) M, n = 6) induced similar responses to those observed in normal tissues (initial rate: 82.5 +/- 27.5 DE/min, 18.8 +/- 4.1 DE in 5 min). We conclude that human nasal and tracheobronchial goblet cells are stimulated by mucosal nucleotides, probably via a 5'-nucleotide receptor, and that this response is unaffected by CF.
Activation by Extracellular Nucleotides of Chloride Secretion in the Airway Epithelia of Patients with Cystic Fibrosis
Creators: name: Clarke, L.L.
name: Boucher, R.C.
name: Knowles, M.R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1991

description: Background. Cystic fibrosis is characterized by abnormal electrolyte transport across the epithelia of the airways. In particular, there is excessive sodium absorption and decient chloride secretion. Drugs that block excessive sodium absorption may provide clinical benefit in cystic fibrosis, but there are no available therapeutic agents to improve chloride secretion. In vitro studies in cultured human-airway epithelia indicate that triphosphate nucleotides (ATP and UTP) induce chloride secretion through apical-membrane purinergic receptors. Methods. We tested the ability of nucleotides to induce chloride secretion in vivo in 9 normal subjects and 12 patients with cystic fibrosis by measuring responses of nasal transepithelial potential difference (PD) to superfusion of nucleotides. Changes in transepithelial bioelectric properties and the permeability of the apical membrane to chloride in response to extracellular (apical) UTP were determined with ion-selective microelectrodes in cultured nasal epithelia. Results. ATP and UTP induced chloride secretion in vivo in both groups. At their maximal effective concentrations of 10–4 M, ATP and UTP were more effective chloride secretagogues in the patients with cystic fibrosis (mean [± change in PD, —19.8±1.4 mV and —15.0±1.7 mV, respectively) than in the normal subjects (—6.9±0.6 mV and —8.1±0.9 mV, respectively). Microelectrode studies established that extracellular UTP stimulated a larger increase in PD and chloride secretory current in epithelial cells from patients with cystic fibrosis than in cells from normal subjects, by actions localized to the apical membrane. Conclusions. Extracellular nucleotides are effective in vivo chloride secretagogues in the nasal epithelia of patients with cystic fibrosis. The equipotency of ATP and UTP suggests that the effect is mediated by P2 nucleotide receptors. Selected nucleotides, such as UTP or nucleotide analogues, should be investigated as therapeutic agents for lung disease in cystic fibrosis.
Canine tracheal epithelial cells express the type 1 insulin-like growth factor receptor and proliferate in response to insulin-like growth factor I.
Creators: name: Boucher, R.C.
name: Retsch-Bogart, G.Z.
name: Moats-Staats, B.M.
name: Stiles, A.D.
name: D'Ercole, A.J.
name: Van Scott, M.R.
Publisher: name: American Lung Association
Year: 1990

description: Disaggregated airway epithelial cells replicate in serum-free media containing supraphysiologic concentrations of insulin. To examine the hypothesis that the type 1 insulin-like growth factor (IGF) receptor mediates the mitogenic action of insulin on these cells, we studied the mitogenic effects of IGF-I and insulin, and the expression of type 1 IGF receptors in primary cultures of adult canine tracheal epithelial cells. Isolated tracheal epithelial cells were grown in varying concentrations of IGF-I or insulin in Ham's F12 medium supplemented with transferrin, cholera toxin, and endothelial cell growth supplement. Both IGF-I and insulin increased DNA synthesis (measured as [3H]thymidine incorporation into DNA) and cell number in a concentration-dependent fashion, but IGF-I was at least 20 to 60 times more potent than insulin in its mitogenic effects. No additive or synergistic effect was observed with the simultaneous addition of IGF-I and insulin in maximally effective doses. A monoclonal antibody directed against the type 1 IGF receptor (alpha IR3) blocked the mitogenic activity of both IGF-I and insulin. Affinity labeling of type 1 IGF receptors by covalent cross-linking with disuccinimidyl suberate demonstrated the tracheal epithelial cell IGF-I binding moiety to have a relative molecular weight of 130,000 D. Binding of [125I]IGF-I to this protein was inhibited by low concentrations of IGF-I, relative to insulin, and by alpha IR3. An 11-kb transcript characteristic of mRNA for the type 1 IGF receptor was recognized in poly(A+) RNA derived from cultured canine tracheal epithelial cells.
title: A review on cranial dural arteriovenous fistula: What radiologists need to know.
Creators: name: Wassef, Shafik
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Fistula
subject: Embolism / Thrombosis
subject: Arteriovenous malformations
subject: Staging
subject: Embolisation
subject: Diagnostic procedure
subject: Catheter venography
subject: Catheter arteriography
subject: Neuroradiology brain
subject: Interventional vascular

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: After review, the user will be familiar with: A- Types of Cranial Dural Arteriovenous Fistula (DAVF). Angiographic grading scales and key angiographic imaging features Natural history, and indication and options for treatment. B- Cross-sectional...
Anomalous Coulomb Drag in Electron-Hole Bilayers due to the Formation of Excitons
Creators: name: Efimkin, Dmitry K.
name: Galitski, Victor
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Several recent experiments have reported an anomalous temperature dependence of the Coulomb drag effect in electron-hole bilayers. Motivated by these puzzling data, we study theoretically a low-density electron-hole bilayer, where electrons and holes avoid quantum degeneracy by forming excitonic molecules. We describe the ionization-recombination crossover between the electron-hole plasma and exciton gas and calculate both the intralayer and drag resistivity as a function of temperature. The latter exhibits a minimum followed by a sharp upturn at low temperatures in a qualitative agreement with the experimental observations [see, e.g., J. A. Seamons et al., Phys. Rev. Lett. 102, 026804 (2009)]. Importantly, the drag resistivity in the proposed scenario is found to be rather insensitive to a mismatch in electron and hole concentrations in sharp contrast to the scenario of electron-hole Cooper pairing.
description: 7 pages, 4 figures. Minor changes. Published version
title: The usefulness of PET-CT in staging and restaging in carcinoma prostate.
Creators: name: Flores, Marco
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Cancer
subject: Education
subject: PET-CT
subject: Genital / Reproductive system male

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Recognize the potential role of PET-CT in the evaluation of patients with prostate cancer. Analyze the useful of PET-CT spectrum in staging of prostate...
Multidimensional quantum tunneling in the Schwinger effect
Creators: name: Dumlu, Cesim K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We study the Schwinger effect, in which the external field having a spatiotemporal profile creates electron-positron pairs via multidimensional quantum tunneling. Our treatment is based on the trace formula for the QED effective action, whose imaginary part is represented by a sum over complex worldline solutions. The worldlines are multiperiodic, and the periods of motion collectively depend on the strength of spatial and temporal inhomogeneity. We argue that the classical action that leads to the correct tunneling amplitude must take into account both the full period, $\tilde{T}$ and the first fundamental period, $T_1$. In view of this argument we investigate pair production in an exponentially damped sinusoidal field and find that the initial momenta for multiperiodic trajectories lie on parabolic curves, such that on each curve the ratio $\tilde{T}/T_1$ stays uniform. Evaluation of the tunneling amplitude using these trajectories shows that vacuum decay rate is reduced by an order of magnitude, with respect to the purely time-dependent case, due to the presence of magnetic field.
description: 6 pages, 4 figures. Revised and extended
Expression of mucin synthesis and secretion in human tracheobronchial epithelial cells grown in culture.
Creators: name: McDonald, R.J.
name: St George, J.A.
name: Kurland, G.
name: Wu, R.
name: Cross, C.E.
name: Last, J.A.
name: Martin, W.R.
name: Boucher, R.
name: Robinson, C.B.
name: Plopper, C.G.
Publisher: name: American Lung Association
Year: 1990

description: The effects of culture conditions on growth and differentiation of human tracheobronchial epithelial (HTBE) cells have been defined. Epithelial cells were dissociated from tissues by protease treatment and were plated on tissue culture dishes in F12 medium supplemented with insulin, transferrin, epidermal growth factor, hydrocortisone, cholera toxin, bovine hypothalamus extract, and retinol. HTBE cells did not express any mucociliary function (ciliogenesis or mucin secretion) on tissue culture plastic, but they could be passaged 3 to 5 times with a total of 10 to 25 population doublings. Cells from early passages re-express both these functions when transplanted to tracheal grafts. When tissue culture plates were coated with collagen film or collagen gel substrata, cell attachment and proliferation were stimulated. However, the expression of mucous cell function in culture occurred only when cells were plated on collagen gel substrata and vitamin A (retinol) was present in the medium. Mucous cell differentiation under optimal conditions was defined by ultrastructural studies, by immunologic studies with mucin-specific monoclonal antibodies, and by carbohydrate and amino acid compositional analyses of mucin-like glycoproteins purified from culture medium. These results demonstrate for the first time that HTBE cells can express mucin synthesis and secretion under appropriate culture conditions.
(101771) Alexander Morris Carr Saunders
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Carotid-cavernous fistulas: from the pathophysiology and clinical syntomps to the radiologic findings.
Creators: name: Pesquera Muñoz, Alvaro
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Trauma
subject: Fistula
subject: Acute
subject: Diagnostic procedure
subject: Contrast agent-intravenous
subject: Arterial access
subject: MR-Angiography
subject: Fluoroscopy
subject: CT-Angiography
subject: Vascular
subject: Neuroradiology brain
subject: Head and neck

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: First of all, to understand the anatomy as well as the pathofisiology related carotidcavernous fistulas and their syntoms. To know the radiologic findings by vascular imaging studies (orbital Doppler, CT & MRI angiography and cerebral arteriography)...
Prospects for the development of the constitutional right to provide access to documents and materials affecting the rights and freedoms of a citizen of the Russian Federation//Перспективы развития конституционного права на обеспечение доступа к документам и материалам, затрагивающим права и свободы гражданина РФ / Д. И. Наумов, С. В. Шошин // Трансформация права и правоохранительной деятельности в условиях развития цифровых технологий:материалы конференции-Саратов, 2021.-С.с.198-201.
Creators: name: Shoshin, Serguei
name: Naumov, Dmitry
Publisher: name: figshare
Year: 2022
Subjects: subject: 180102 Access to Justice
subject: FOS: Law
subject: 180103 Administrative Law
subject: 180106 Comparative Law
subject: 130302 Comparative and Cross-Cultural Education
subject: FOS: Educational sciences
subject: 180107 Conflict of Laws (Private International Law)
subject: 180108 Constitutional Law
subject: Digital Humanities
subject: 130303 Education Assessment and Evaluation
subject: 139999 Education not elsewhere classified
subject: 130304 Educational Administration, Management and Leadership
subject: 130305 Educational Counselling
subject: 130306 Educational Technology and Computing
subject: 210202 Heritage and Cultural Conservation
subject: FOS: Media and communications
subject: 180114 Human Rights Law
subject: 220104 Human Rights and Justice Issues
subject: FOS: Philosophy, ethics and religion
subject: 180116 International Law (excl. International Trade Law)
subject: 180118 Labour Law
subject: Law
subject: Language
subject: 180119 Law and Society
subject: 180199 Law not elsewhere classified
subject: 130309 Learning Sciences
subject: 220105 Legal Ethics
subject: 180120 Legal Institutions (incl. Courts and Justice Systems)
subject: 180121 Legal Practice, Lawyering and the Legal Profession
subject: 180122 Legal Theory, Jurisprudence and Legal Interpretation

description: Changes are being made to the criminal legislation of Russia. The criminal procedure law of Russia is also frequently amended. Difficulties arise when bringing information about the content of the legal field to the attention of the electorate. The authors propose to expand the areas of explanatory activities in the field of law. The sphere of legal education in modern Russia has a significant space for its further development.
title: Paranasal sinus disease in HIV positive patients: CT evaluation
Creators: name: Rajaram, Akash
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: AIDS
subject: Screening
subject: CT
subject: Neuroradiology brain
subject: Head and neck

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: INTRODUCTION Paranasal sinus (PNS) infection is a common condition affecting HIV positive patients that are frequently overlookedwithout careful evaluation of the imaging features that may suggest a specific pathology. The incidence of PNS disease...
Aerosolized Amiloride for the Treatment of Lung Disease in Cystic Fibrosis
Creators: name: Boucher, R.C.
name: Church, N.L.
name: Helms, R.W.
name: Edwards, L.J.
name: Henkin, J.
name: Gallo, R.L.
name: Waltner, W.E.
name: Gilligan, P.
name: King, M.
name: Yankaskas, J.R.
name: Knowles, M.R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1990

description: To the Editor: The April 26 issue of the Journal presented encouraging results by Knowles et al. regarding the beneficial effects of aerosolized amiloride in the treatment of cystic fibrosis.1 The introduction and discussion sections of this article described the function of amiloride as an inhibitor of sodium transport in the airway epithelium, and the authors suggested that the beneficial effects observed were exerted “at least in part by increasing the clearance of secretions.” Although the results of this investigation were promising in terms of the improvement in the decline of forced vital capacity in patients with cystic fibrosis, this.
Uncertainty analysis and order-by-order optimization of chiral nuclear interactions
Creators: name: Carlsson, B. D.
name: Ekström, A.
name: Forssén, C.
name: Strömberg, D. Fahlin
name: Jansen, G. R.
name: Lilja, O.
name: Lindby, M.
name: Mattsson, B. A.
name: Wendt, K. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: Nuclear Experiment (nucl-ex)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Chiral effective field theory (chiEFT) provides a systematic approach to describe low-energy nuclear forces. Moreover, chiEFT is able to provide well-founded estimates of statistical and systematic uncertainties -- although this unique advantage has not yet been fully exploited. We fill this gap by performing an optimization and statistical analysis of all the low-energy constants (LECs) up to next-to-next-to-leading order. Our optimization protocol corresponds to a simultaneous fit to scattering and bound-state observables in the pion-nucleon, nucleon-nucleon, and few-nucleon sectors, thereby utilizing the full model capabilities of chiEFT. We study the effect on other observables by demonstrating error-propagation methods that can easily be adopted by future works. We employ mathematical optimization and implement automatic differentiation to attain efficient and machine-precise first- and second-order derivatives of the objective function with respect to the LECs. We use power-counting arguments to estimate the systematic uncertainty that is inherent to chiEFT and we construct chiral interactions at different orders with quantified uncertainties. Statistical error propagation is compared with Monte Carlo sampling showing that statistical errors are in general small compared to systematic ones. In conclusion, we find that a simultaneous fit to different sets of data is critical to (i) identify the optimal set of LECs, (ii) capture all relevant correlations, (iii) reduce the statistical uncertainty, and (iv) attain order-by-order convergence in chiEFT. Furthermore, certain systematic uncertainties in the few-nucleon sector are shown to get substantially magnified in the many-body sector; in particlar when varying the cutoff in the chiral potentials. The methodology and results presented in this Paper open a new frontier for uncertainty quantification in ab initio nuclear theory.
description: Accepted for publication in Physical Review X. This version includes Supplemental Material
title: Voces: Experiences of Undocumented Latines
Creators: name: González Vera, José Manuel
Publisher: name: Utah State University
Year: 2022

description: The purpose of this study was to learn about the challenges that this community faced before the pandemic and how they coped through those challenges. To answer this question, I examined transcripts from group interviews collected in the state of Texas. In total, there were 67 participants, many of whom were undocumented (n = 49) while the others had a relative or friend who was undocumented. Data were analyzed by looking for common patterns and themes in the transcripts, and guided by Critical Race Theory, Latine Critical Theory, and Undocumented Critical Theory. Results suggest that psychological distress is common not only for undocumented people but also for their loved ones who are not undocumented. Another major challenge was feeling limited by their undocumented status. Some undocumented participants also emphasized that they had been discriminated against by others, including by other Latines. Moreover, family was highly valued in this community, however, some participants stated that they felt disconnected from their families. In terms of strengths, results showed that problem solving is a major coping strategy for this community. Additionally, many participants reported using religion to remain hopeful and optimistic about their future.
title: Radiographic parameters for predicting early flow disturbances during haemodialysis in tunneled catheters
Creators: name: Fahnert, Jeanette
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Haemodynamics / Flow dynamics
subject: Localisation
subject: Diagnostic procedure
subject: Conventional radiography
subject: Lung

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The incidence of end-stage renal disease (ESRD) is increasing continuously. An appropriate vascular access with a high flow is necessary when patients develop terminal renal failure resulting in the need for haemodialysis (HD). An arteriovenous...
A Pilot Study of Aerosolized Amiloride for the Treatment of Lung Disease in Cystic Fibrosis
Creators: name: Edwards, L.J.
name: Knowles, M.R.
name: Gilligan, P.
name: Waltner, W.E.
name: Yankaskas, J.R.
name: Church, N.L.
name: Boucher, R.C.
name: King, M.
name: Helms, R.W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1990

description: Excessive active absorption of sodium is a unique abnormality of the airway epithelium in patients with cystic fibrosis. This defect is associated with thickened mucus and poor clearance of airway secretions and may contribute to the pulmonary disease in these patients. To study whether the inhibition of excessive absorption of sodium might affect the course of lung disease in cystic fibrosis, we performed a double-blind, crossover trial comparing aerosolized amiloride (5 mmol per liter; 3.5 ml four times daily), a sodium-channel blocker, with vehicle alone. Fourteen of the 18 adult patients initially enrolled in the study completed the one-year trial (25 weeks for each treatment). The mean (±SEM) loss of forced vital capacity (FVC) was reduced from 3.39±1.13 ml per day during treatment with vehicle alone to 1.44±0.67 ml per day during treatment with amiloride (P<0.04). A measured index of sputum viscosity and elasticity was abnormal during treatment with vehicle alone and improved during treatment with amiloride. Calculated indexes of mucociliary and cough clearance also improved during amiloride treatment. No systemic, respiratory, or subjective toxic effects of amiloride were noted. We conclude from this preliminary study that aerosolized amiloride can be safely administered to adults with cystic fibrosis. The slowing of the loss of FVC and the improvement in sputum viscosity and elasticity suggest a beneficial clinical effect. Aerosolized amiloride deserves further evaluation in the treatment of lung disease in patients with cystic fibrosis.
(101765) William Smoult Robison
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Chloride secretory response of cystic fiboris human airway epithelia. Preservation of calcium but not protein kinase C- and A-dependent mechanisms
Creators: name: Earp, H.S.
name: Paradiso, A.M.
name: Boucher, R.C.
name: Knowles, M.R.
name: Cheng, E.H.C.
name: Stutts, M.J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1989

description: Because the defect in Cl- secretion exhibited by cystic fibrosis (CF) epithelia reflects the regulatory rather than conductive abnormalities of an apical membrane Cl- channel, we investigated the role of different regulatory pathways in the activation of Cl- secretion in freshly excised normal and CF nasal epithelia mounted in Ussing chambers. A β agonist (isoproterenol [ISO]), a Ca2+ ionophore (A23187), and a phorbol ester (PMA) were all effective Cl- secretagogues in normal human nasal epithelia. Agonist addition studies indicated that ISO and PMA but not A23187 may share a common regulatory pathway. In contrast, only A23187 induced Cl- secretion in CF epithelia. Bradykinin raised cytosolic Ca2+ and induced Cl- secretion in both normal and CF tissues, indicating that receptor gated Ca2+ dependent Cl- secretory mechanisms were preserved in CF. The defective Cl- secretory response in CF epithelia to ISO and PMA did not reflect abnormalities in cAMP-dependent (A) and phospholipid Ca2+-dependent (C) kinase activities. We conclude that (a) a Ca2+-sensitive mechanism for regulating Cl- secretion is maintained in CF airway epithelia, and (b) a regulatory pathway shared by two distinct protein kinases is defective in CF, indicating that the CF genetic lesion is not tightly coupled to a single (e.g., cAMP dependent) regulatory mechanism.
Electrical Properties of Tracheal Epithelium in Cystic Fibrosis
Creators: name: Widdicombe, J.H.
name: Davis, B.
name: Nathanson, I.
name: Knowles, M.R.
name: Gatzy, J.T.
name: Boucher, R.C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1982

description: To the Editor: As reported by Knowles et al. in the issue of December 17, 1981, in vivo measurements of potential difference across the trachea in patients with cystic fibrosis were significantly greater than in control subjects. (P<0.05).* Superfusion of the luminal surface of the trachea with amiloride (10-4 M) reduced the potential difference by 85 per cent in patients, as compared with 25 per cent in controls, suggesting that the increased potential difference in cystic fibrosis is due to an increase in amiloride-sensitive sodium absorption.
title: Percutaneous cholecystostomy: 22-year experience of transperitoneal approach. Evaluation of advantages and disadvantages.
Creators: name: Lorenzo Górriz, Antonio
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Obstruction / Occlusion
subject: Calcifications / Calculi
subject: Puncture
subject: Cholangiography
subject: Drainage
subject: Ultrasound
subject: Fluoroscopy
subject: Interventional non-vascular
subject: Biliary Tract / Gallbladder
subject: Abdomen

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Cholecystectomy is the definitive treatment for patients with acute cholecystitis. It´s a surgery with scarce mortality (0.8%) in patients with no surgical risk, but this mortality raises to 18% in cases with high surgical risk. There is a...
title: And what about MELAS syndrome? – the role of the radiologist
Creators: name: Edwards, Nathan
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: CNS
subject: Neuroradiology brain
subject: CT
subject: MR
subject: MR-Spectroscopy
subject: Education
subject: Education and training
subject: Genetic defects

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To describe the epidemiology, clinical features and pathology of mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome. To highlight the radiological features of MELAS syndrome. To understand the role of the...
title: Follow-up imaging in patients with surgically treated rectal cancer: what the radiologist needs to know
Creators: name: Pop, Calin
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Neoplasia
subject: Multidisciplinary cancer care
subject: Metastases
subject: Treatment effects
subject: Staging
subject: Radiation therapy / Oncology
subject: Ultrasound
subject: MR
subject: CT
subject: Pelvis
subject: Oncology
subject: Colon

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The aim of this poster is to review and highlight through relevant images: The common surveillance strategies after treatment in patients with surgically treated rectal cancer for early detection of recurrence The current state of the art imaging...
Encapsulation in human and murine erythrocytes of the Synomag®-D-PEG-OMe tracer for MPI application
Creators: name: Antonelli, Antonella
name: Scarpa, Emanuele Salvatore
name: Di Corato, Riccardo
name: Abdalla, Pasant
name: Thieben, Florian
name: Grüttner, Cordula
name: Knopp, Tobias
name: Magnani, Mauro
Publisher: name: International Journal on Magnetic Particle Imaging
Year: 2022

description: Recently, the potential of red blood cells (RBCs) loaded with superparamagnetic iron oxide (SPIO)-based nanoparticles as new blood-pool tracer material for the Magnetic Particle Imaging (MPI) has been investigated. It was shown that the encapsulation of SPIO-based contrast agents in the RBCs increase the circulation time in blood of these nanomaterials. However, not all iron oxide nanoparticles are eligible to the encapsulation into RBCs, depending on several factors such as dispersant agent nature, nanoparticle size and synthesis protocol. Therefore, we have recently started a program to identify those nanoparticles that can be potentially loaded with our method into RBCs. The goal is to produce biocompatible SPIO-RBCs carriers that can be used as new intravascular magnetic susceptible agents in biomedical applications, such as MRI and MPI. Here, we report the in vitro results obtained by using the Synomag®-D-PEG-OMe nanoparticle suspension (micromod Partikeltechnologie GmbH) with both human and murine red blood cells. MPS analysis showed that human Synomag®-D-PEG-OMe-loaded RBCs produced a signal that is weaker respect to the remarkable signal obtained with ferucarbotran loaded-RBCs prepared at the same condition, but it is to be noted that the encapsulation efficiency of Synomag®-D-PEG-OMe into cells is lower compared to ferucarbotran nanoparticles. Int. J. Mag. Part. Imag. 8(1), 2022, Article ID: 2209001, DOI: 10.18416/IJMPI.2022.220900
description: International Journal on Magnetic Particle Imaging, Vol 8 No 1 (2022)
(101766) Georgiana Adelaide Robison
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Potential Difference across Respiratory Epithelia in Cystic Fibrosis
Creators: name: al-Bazzaz, F.
name: Knowles, M.R.
name: Boucher, R.C.
name: Gatzy, J.T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1982

description: To the Editor: In their paper describing increased electric potential difference across respiratory epithelia in cystic fibrosis (December 17 issue1) Knowles et al. mentioned that the time course of indomethacin's action on the bioelectric properties of respiratory epithelia was not well documented. This is not correct; we have previously reported details of indomethacin's effect on electrical properties and on transport of sodium and chloride across canine tracheal mucosa in vitro.
(101762) Emma Saunders
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Increased Bioelectric Potential Difference across Respiratory Epithelia in Cystic Fibrosis
Creators: name: Knowles, M.
name: Gatzy, J.
name: Boucher, R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1981

description: To investigate respiratory epithelial function in cystic fibrosis, we measured the transepithelial electrical potential difference across the upper and lower respiratory mucosa in patients with cystic fibrosis and control subjects. The nasal potential difference in the 24 patients with cystic fibrosis exceeded by more than 3 standard deviations the mean voltage in healthy controls, subjects with other diseases, and subjects heterozygous for cystic fibrosis. Potential differences in lower airways were measured in four patients and were significantly greater than in controls (P<0.05). Superfusion of the luminal surface with amiloride, an inhibitor of active sodium absorption, induced greater reductions in both nasal and airway potential differences in patients than in controls. We conclude that the increased respiratory-epithelial potential differences appear to be a specific abnormality in homozygotes for cystic fibrosis. The greater reduction in potential difference in response to amiloride suggests that absorption of excess salt and perhaps liquid from respiratory epithelial surfaces contributes to the pathogenesis of lung disease in cystic fibrosis. (N Engl J Med. 1981; 305:148995.). Abnormalities in the electrolyte and water content of luminal liquid or “secretions” of the airways, sweat glands, intestinal and reproductive tracts, and pancreas suggest that cystic fibrosis is characterized by a generalized epithelial dysfunction. Airway secretions are tenacious and excessively thick. Although a search for the cause of this abnormal surface liquid has failed to identify unique mucus glycoproteins, altered electrolyte composition and lower water content (“dehydration“) of airway secretions from patients with cystic fibrosis have been reported.
Cosmological constraints on the neutron lifetime
Creators: name: Salvati, Laura
name: Pagano, Luca
name: Consiglio, Rosa
name: Melchiorri, Alessandro
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We derive new constraints on the neutron lifetime based on the recent Planck 2015 observations of temperature and polarization anisotropies of the CMB. Under the assumption of standard Big Bang Nucleosynthesis, we show that Planck data constrains the neutron lifetime to $τ_n=(907 \pm 69) \, [\text{s}]$ at $68 \%$ c.l.. Moreover, by including the direct measurements of primordial Helium abundance of Aver et al. (2015) and Izotov et al. (2014), we show that cosmological data provide the stringent constraints $τ_n=(875 \pm 19) \, [\text{s}]$ and $τ_n=(921 \pm 11) \, [\text{s}]$ respectively. The latter appears to be in tension with neutron lifetime value quoted by the Particle Data Group ($τ_n=(880.3 \pm 1.1) \, [\text{s}]$). Future CMB surveys as COrE+, in combination with a weak lensing survey as EUCLID, could constrain the neutron lifetime up to a $\sim 6 \, [\text{s}]$ precision.
description: 13 pages, 3 figures. Matching JCAP accepted version
(101764) Richard Jones
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Comparative analysis of the legal status and practice of protecting the interests of consumers of financial services in Russia and the USA //Шошин, С. В. Компаративистский анализ правового положения и практики защиты интересов потребителей финансовых услуг в России и США // Защита прав потребителей финансовых услуг: проблемы взаимодействия органов публичной власти : Сборник научных трудов по материалам Международной конференции -Саратов: СГЮА, 2021. – С. 162-170.
Creators: name: Shoshin, Serguei
Publisher: name: figshare
Year: 2022
Subjects: subject: 180102 Access to Justice
subject: FOS: Law
subject: 180103 Administrative Law
subject: 220102 Business Ethics
subject: FOS: Philosophy, ethics and religion
subject: 220201 Business and Labour History
subject: 180104 Civil Law and Procedure
subject: 180106 Comparative Law
subject: 180108 Constitutional Law
subject: 180107 Conflict of Laws (Private International Law)
subject: 180109 Corporations and Associations Law
subject: 180110 Criminal Law and Procedure
subject: 180112 Equity and Trusts Law
subject: 180114 Human Rights Law
subject: 220104 Human Rights and Justice Issues
subject: 180116 International Law (excl. International Trade Law)
subject: Law
subject: 180119 Law and Society
subject: 180199 Law not elsewhere classified
subject: 220105 Legal Ethics
subject: 180120 Legal Institutions (incl. Courts and Justice Systems)
subject: 180121 Legal Practice, Lawyering and the Legal Profession
subject: 180122 Legal Theory, Jurisprudence and Legal Interpretation
subject: 180123 Litigation, Adjudication and Dispute Resolution
subject: 180125 Taxation Law
subject: 180126 Tort Law

description: Financial consumer protection in both Russia and the United States has many similarities. For example, from monopolistic activity, deposit insurance problems. Differences in the history of the existence of the Deposit Insurance Agency in Russia and the Federal Deposit Insurance Corporation in the United States contribute to the identification and features of the legal regime.