title: ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ ÐºÐ¾Ð¼ÐµÐ½Ð¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¸Ð¼Ð¸ Ð¼ÐµÑÐ¾Ð´Ð°Ð¼Ð¸
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Study of comenic acid by optical methods
Creators: name: ÐÐ¸Ð²Ð¸Ð½Ð°, ÐÐ²Ð³ÐµÐ½Ð¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: ÐºÐ¾Ð¼ÐµÐ½Ð¾Ð²Ð°Ñ ÐºÐ¸ÑÐ»Ð¾ÑÐ°
Ð¸Ð½ÑÐµÐºÑÐ¸Ð¾Ð½Ð½Ð°Ñ Ð»ÐµÐºÐ°ÑÑÑÐ²ÐµÐ½Ð½Ð°Ñ ÑÐ¾ÑÐ¼Ð°
Ð»Ð°Ð·ÐµÑÐ½ÑÐ¹ ÐºÐ¾Ð½ÑÐ¾ÐºÐ°Ð»ÑÐ½ÑÐ¹ ÑÐºÐ°Ð½Ð¸ÑÑÑÑÐ¸Ð¹ Ð¼Ð¸ÐºÑÐ¾ÑÐºÐ¾Ð¿
Ð²Ð¸Ð·ÑÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ
Ð°Ð²ÑÐ¾ÑÐ»ÑÐ¾ÑÐµÑÑÐµÐ½ÑÐ¸Ñ
ÑÐ¿ÐµÐºÑÑÐ°Ð»ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð·
Ð°ÑÐ³Ð¾Ð½Ð¾Ð²ÑÐ¹ Ð»Ð°Ð·ÐµÑ
Ð´Ð¸Ð¾Ð´Ð½ÑÐ¹ Ð»Ð°Ð·ÐµÑ
dpss Ð»Ð°Ð·ÐµÑ
Ð¼Ð¾Ð´ÐµÐ»Ñ ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÑÐ¾Ð²Ð½ÐµÐ¹
comenic acid
injectable dosage form
laser confocal scanning microscope
visualization
autofluorescen
spectral analysis
argon laser
diode laser
dpss laser
energy level model

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¸ ÑÐµÐ³Ð¸ÑÑÑÐ°ÑÐ¸Ð¸ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾Ð¹ Ð°Ð²ÑÐ¾ÑÐ»ÑÐ¾ÑÐµÑÑÐµÐ½ÑÐ¸Ð¸ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ð¾Ð² ÐºÐ¾Ð¼ÐµÐ½Ð¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ Ð¿ÑÐ¸ Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ð¸ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÐ¼Ð¸ Ð»Ð°Ð·ÐµÑÐ°Ð¼Ð¸. ÐÐ°Ð´Ð°ÑÐ¸, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐµÑÐ°Ð»Ð¸ÑÑ Ð² ÑÐ¾Ð´Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ: 1. ÐÐ¸Ð·ÑÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ð¾Ð² ÐºÐ¾Ð¼ÐµÐ½Ð¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ Ð² Ð¿ÑÐ¾ÑÐ¾Ð´ÑÑÐµÐ¼ ÑÐ²ÐµÑÐµ. 2. ÐÐ±Ð»ÑÑÐµÐ½Ð¸Ðµ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ð¾Ð² ÐºÐ¾Ð¼ÐµÐ½Ð¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ ÑÐ°Ð·Ð½ÑÐ¼Ð¸ Ð»Ð°Ð·ÐµÑÐ°Ð¼Ð¸ Ð¸ ÑÐµÐ³Ð¸ÑÑÑÐ°ÑÐ¸Ñ Ð°Ð²ÑÐ¾ÑÐ»ÑÐ¾ÑÐµÑÑÐµÐ½ÑÐ¸Ð¸ Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÐºÐ¾Ð½ÑÐ¾ÐºÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÑÐºÐ°Ð½Ð¸ÑÑÑÑÐµÐ³Ð¾ Ð¼Ð¸ÐºÑÐ¾ÑÐºÐ¾Ð¿Ð° LSM 710. 3. ÐÐ¾ÑÑÑÐ¾ÐµÐ½Ð¸Ðµ ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð¼Ð¾Ð´ÐµÐ»Ð¸ ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÑÐ¾Ð²Ð½ÐµÐ¹ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ð¾Ð² ÐºÐ¾Ð¼ÐµÐ½Ð¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ. Ð Ð°Ð±Ð¾ÑÐ° Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° Ð½Ð° Ð»Ð°Ð·ÐµÑÐ½Ð¾Ð¼ ÐºÐ¾Ð½ÑÐ¾ÐºÐ°Ð»ÑÐ½Ð¾Ð¼ ÑÐºÐ°Ð½Ð¸ÑÑÑÑÐµÐ¼ Ð¼Ð¸ÐºÑÐ¾ÑÐºÐ¾Ð¿Ðµ LSM 710 Ð¦ÐÐ Â«ÐÐ¾Ð½ÑÐ¾ÐºÐ°Ð»ÑÐ½Ð°Ñ Ð¼Ð¸ÐºÑÐ¾ÑÐºÐ¾Ð¿Ð¸ÑÂ» ÐÐ½ÑÑÐ¸ÑÑÑÐ° ÑÐ¸Ð·Ð¸Ð¾Ð»Ð¾Ð³Ð¸Ð¸ Ð¸Ð¼. Ð.Ð. ÐÐ°Ð²Ð»Ð¾Ð²Ð° Ð ÐÐ. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ ÑÐ´Ð°Ð»Ð¾ÑÑ Ð²Ð¸Ð·ÑÐ°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°ÑÑ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ñ ÐºÐ¾Ð¼ÐµÐ½Ð¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ, Ð° ÑÐ°ÐºÐ¶Ðµ Ð·Ð°ÑÐ¸ÐºÑÐ¸ÑÐ¾Ð²Ð°ÑÑ ÑÐ²Ð»ÐµÐ½Ð¸Ðµ Ð°Ð²ÑÐ¾ÑÐ»ÑÐ¾ÑÐµÑÑÐµÐ½ÑÐ¸Ð¸ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ð¾Ð² ÐºÐ¾Ð¼ÐµÐ½Ð¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ Ð¿ÑÐ¸ Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ð¸ Ð´Ð¸Ð¾Ð´Ð½ÑÐ¼, Ð°ÑÐ³Ð¾Ð½Ð¾Ð²ÑÐ¼ Ð¸ DPSS Ð»Ð°Ð·ÐµÑÐ°Ð¼Ð¸. ÐÐ° Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ð¸ ÑÐ¿ÐµÐºÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð±ÑÐ»Ð° Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð° ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ°Ñ Ð¼Ð¾Ð´ÐµÐ»Ñ ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÑÐ¾Ð²Ð½ÐµÐ¹, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÑÐ¾ÑÐ¼ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð° Ð³Ð¸Ð¿Ð¾ÑÐµÐ·Ð°, Ð¾Ð±ÑÑÑÐ½ÑÑÑÐ°Ñ, ÑÐµÐ¼ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÑÐµÑÑÑ Ð´Ð¸Ð°Ð¿Ð°Ð·Ð¾Ð½ ÑÐ²ÐµÑÐ½Ð¾ÑÑÐ¸ Ð³Ð¾ÑÐ¾Ð²Ð¾Ð¹ Ð»ÐµÐºÐ°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð¹ ÑÐ¾ÑÐ¼Ñ, Ð¸Ð·Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð½Ð¾Ð¹ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÐºÐ¾Ð¼ÐµÐ½Ð¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ.
description: This work is devoted to the study and registration of the possible autofluorescence of the comenic acid under irradiation with various lasers. The tasks that were solved during the study: 1. The Visualization of crystals of comenic acid in transmitted light. 2. The Irradiation of crystals of comenic acid with different lasers and registration of autofluorescence by using a confocal scanning microscope LSM 710. 3. The Construction of a physical model of energy levels of the crystals of comenic acid. The work was carried out on a laser confocal scanning microscope LSM 710 (The community center Â«Confocal microscopyÂ» Pavlov Physiological Institute RAS). As a result, it was possible to visualize crystals of comenic acid, as well as to record the phenomenon of autofluorescence of crystals of comenic acid under irradiation with diode, argon and DPSS lasers. On the basis of spectral analysis, a model of energy levels was constructed. We formulated a hypothesis by which the color of the medicine based on comenic acid is determined.