cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Photoacoustic pump-probe tomography of fluorophores in vivo using interleaved image acquisition for motion suppression
Creators: name: Maerk, Julia
name: Wagener, Asja
name: Zhang, Edward
name: Laufer, Jan
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: In fluorophores, the excited state lifetime can be modulated using pump-probe excitation. By generating photoacoustic (PA) signals using simultaneous and time-delayed pump and probe excitation pulses at fluences below the maximum permissible exposure, a modulation of the signal amplitude is observed in fluorophores but not in endogenous chromophores. This provides a highly specific contrast mechanism that can be used to recover the location of the fluorophore using difference imaging. The practical challenges in applying this method to in vivo PA tomography include the typically low concentrations of fluorescent contrast agents, and tissue motion. The former results in smaller PA signal amplitudes compared to those measured in blood, while the latter gives rise to difference image artefacts that compromise the unambiguous and potentially noise-limited detection of fluorescent contrast agents. To address this limitation, a method based on interleaved pump-probe image acquisition was developed. It relies on fast switching between simultaneous and time-delayed pump-probe excitation to acquire PA difference signals in quick succession, and to minimise the effects of tissue motion. The feasibility of this method is demonstrated in tissue phantoms and in initial experiments in vivo.
Can post-splenectomy thrombocytosis mask essential thrombocythaemia?
Creators: name: Langabeer, Stephen E.
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2020
Subjects: splenectomy
thrombocythosis
essential thrombocythaemia

description: EXCLI Journal; 19:Doc773; ISSN 1611-2156
Source_codes_data
Creators: name: Qian, Yuehui
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 460605
subject: Distributed systems and algorithms
classificationCode: 490412
subject: Topology
classificationCode: 401302
subject: Geospatial information systems and geospatial data modelling

description: Terrain topology plays an important role in simulations and segmentation. A widely used terrain representation is the Triangulated Irregular Network (TIN). However, topological analysis on TINs is challenging due to high time and memory requirements, which limit the size of the terrain that can be analyzed.
We address this problem by introducing a novel framework for efficient and scalable analysis of large TINs based on Morse theory using Apache Spark. The proposed framework, named Morse-Spark, is based on a novel data structure for encoding the minimal information of a TIN, and integrates efficient algorithms for computing terrain morphology. To evaluate the effectiveness and scalability of such a framework, we compare Morse-Spark against a vanilla Spark implementation and three well-established software libraries for the topological analysis of TINs through a comprehensive set of experiments. Our experimental evaluation with real-world TINs shows that Morse-Spark can effectively handle datasets at least 20 times larger than existing approaches.
ТРАНСФОРМАЦИЯ ХУДОЖЕСТВЕННЫХ ЖАНРОВ СОВРЕМЕННОГО ОТЕЧЕСТВЕННОГО ТЕЛЕВИДЕНИЯ
Creators: name: Беликова Анна Игоревна
Publisher: name: Медиасреда
Year: 2020
Subjects: трансформация
жанр
шоу
инфотейнмент

description: Статья посвящена проблеме размывания жанровых границ в художественных жанрах. Автор рассматривает такие способы трансформации, как инфотейнмент, интерактивность, появление на телевидении мемов, инфографики и другие. Подробнее останавливается на сатирических программах, кулинарных шоу и путевых очерках. Эти жанры рассматриваются на примерах программ «Международная пилорама», «Адская кухня» и «Орел и решка».
Effective tools for transparent synchronous collaborative environments.
Creators: name: Yang, Dongsheng.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Computer Science.

description: Synchronous collaborative environments can provide an identical visual and operable working area among geographically separated participants. There are two basic approaches for providing a shared workspace. The first one, collaborative-aware approach, relies on the development of collaborative-aware applications that directly support multiple simultaneously active user inputs and synchronization of outputs to all participants. The second one, collaborative-unaware approach, introduces some intermediate layers between existing single-user applications and the underlying window management system. These layers enable single-user applications to be shared transparently. In order to reuse the large amount of existing single-user applications, most users choose the collaborative-unaware approach. However, to build collaborative-unaware systems to share single-user applications transparently is a great challenge. This thesis describes the design and implementation of some transparent synchronous collaborative tools. They are: (1) the latecomer support for Java applications, Java applets and JMF players; (2) the client synchronization to minimize data transmission latency; (3) the light-weight multi-session support to let different collaboration groups work at the same time and (4) the collaborative VRML viewer to integrate the blaxxun3D VRML viewer with collaboration systems. These tools optimize existing transparent synchronous collaboration systems and make them more realistic, more complete and more generic.
The Relationship of Duffy Gene Polymorphism with High-Sensitivity C-Reactive Protein, Mortality, and Cardiovascular Outcomes in Black Individuals
Creators: name: Seeman, Teresa
name: Tuftin, Bjoernar
name: Peterson, Stephen J.
name: Raffield, Laura M.
name: Kelsey, Karl
name: Parikh, Manish A.
name: Briggs, Matt
name: Ha, Edward T.
name: Taylor, Kent D.
name: Reiner, Alex P.
name: Post, Wendy S.
name: Tahir, Usman A.
name: Carson, April P.
name: Rotter, Jerome I.
name: Kooperberg, Charles
name: Wilson, James G.
name: Haessler, Jeffery
name: Auer, Paul
name: Gerszten, Robert E.
name: Rich, Stephen S.
Publisher: name: Multidisciplinary Digital Publishing Institute (MDPI)
Year: 2024

description: Background: Black adults have higher incidence of all-cause mortality and worse cardiovascular disease (CVD) outcomes when compared to other U.S. populations. The Duffy chemokine receptor is not expressed on erythrocytes in a large majority of Black adults, but the clinical implications of this are unclear. Methods: Here, we investigated the relationship of Duffy receptor status, high-sensitivity C-reactive protein (hs-CRP), and mortality and incident CVD events (coronary heart disease, stroke, and heart failure) in self-identified Black members of three contemporary, longitudinal cohort studies (the Women’s Health Initiative, Jackson Heart Study, and Multi-Ethnic Study of Atherosclerosis). Data on 14,358 Black participants (9023 Duffy-null and 5335 Duffy-receptor-positive, as defined using single-nucleotide polymorphism (SNP) rs2814778) were included in this analysis. Results: Duffy null was strongly associated with higher hs-CRP (meta-analysis p = 2.62 × 10−9), but the association was largely attenuated, though still marginally significant (p = 0.005), after conditioning on known CRP locus alleles in linkage disequilibrium with the Duffy gene. In our discovery cohorts, Duffy-null status appeared to be associated with a higher risk of all-cause mortality and incident stroke, though these associations were attenuated and non-significant following adjustment for traditional risk factors including hs-CRP. Moreover, the association of Duffy-null status with mortality could not be replicated in an independent sample of Black adults from the UK Biobank. Conclusions: These findings suggest that the higher levels of hs-CRP found in Duffy-null individuals may be in part independent of CRP alleles known to influence circulating levels of hs-CRP. During the follow-up of this community-based sample of Black participants, Duffy-null status was not associated with mortality or incident CVD events independently of traditional risk factors including hs-CRP.
МЕДИА В СИСТЕМЕ СОВРЕМЕННОЙ КУЛЬТУРЫ
Creators: name: Высоцкий Вадим Борисович
Publisher: name: Медиасреда
Year: 2020
Subjects: система культуры; массмедиа; медиасреда; субъекты и объекты коммуникации.

description: СМИ представляют собой важнейшую составляющую трансляционного уровня суперсистемы культуры. Журналистика становится все более презентативной и влиятельной областью культуры, так как с её помощью формируется особое социокультурное пространство – медиасреда. Медиасфера играет большую роль не только в статической модели культуры, но и в процессах её динамики, что особенно проявляется на современном этапе цивилизационного развития.
Regulation and performance of the microfinance industry
Creators: name: Morshed, Zakir
Publisher: name: Swinburne
Year: 2024

description: A major change to the regulatory regime in the microfinance industry in Bangladesh occurred when the Microcredit Regulatory Authority Act was enacted in 2006. Under the Act, microfinance institutions had to register with the Authority. Using as its theoretical underpinning responsive regulation and stakeholder theories, this study investigates differential governance and performance outcomes at both organisational and client level for institutions that did and did not register. The findings reveal that registered institutions perform comparatively better in terms of governance practices, outreach and financial sustainability and that their clients' financial literacy and financial status is better than for unregistered institutions.
Misinformed through Mass Avoidance: The Sanitization of Racial Oppression in Massachusetts and Mississippi Social Studies Content Standards
Creators: name: Jelden, Sofie
Publisher: name: Brandeis University
Year: 2023
Subjects: social studies standards
anti-racism
subdued recalls
sanitization of racial oppression

description: Debates on the purpose of education and social studies curriculum, alongside conversations about how to effectively teach race in curriculum are all interconnected. Social studies standards have become a critical tool in informing students of history, yet these past debates have now shifted into modern disputes over the implementation of addressing power, oppression, and racism. Through an analysis of Mississippi and Massachusetts’ social studies standards from two distinct time-periods, this research seeks to uncover how anti-racist frameworks are employed during topics of race, racism, and racial oppression. Through careful coding and qualitative content analysis I used 18 total DEI terms, court cases, and other race related phrases to obtain 100 quotations from the initial sample, employing 3 patterns (latent content codes): Anti-Racist, Black-Centered Education, Attempt, and Failure. There were three key findings based off these latent content codes. The Anti-Racist, Black-Centered Education coded quotations often failed to prompt discussion on the long-term implications of racism or address how systems of racial oppression inform the present-day. Attempt coded quotations utilized an aversive racist framework that consistently provided sanitized, subdued recalls of oppression, specifically when discussing Reconstruction, Jim Crow, and white resistance. Failure quotations typically employed colorblind racism during discourse on “diversity” and “equality,” by using seemingly “positive” words to gloss over discussions of racial oppression. These findings show how standards contribute to the historical maintenance of white-centered recounts and provide guidance on the adoption of anti-racist curricula frameworks.
Influence of phase orientation on dynamic interfacial tension measured by drop volume tensiometry.
Creators: name: Wu, Dongmin.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Engineering, Chemical.

description: During surfactant flooding and caustic water flooding, the interfacial tension (IFT) between the oil and the aqueous phase plays an important role. In the present thesis, the effect of phase orientation on the dynamic IFT between the two phases has been investigated by using the method of drop volume tensiometry (DVT). Two distinct model systems have been studied. The first system is formed by the partially miscible system composed of butanol-1 and water. With butanol-rich (butanol-1 saturated by water) as the dispersed phase and water-rich (water saturated by butanol-1) as the continuous phase, the IFT is 1.70 $\pm$ 0.02 mN/m. The IFT for water-rich as dispersed phase is almost identical at 1.72 $\pm$ 0.03 mN/m. Addition of a surfactant, sodium dodecyl sulfate (SDS), to the system has also been studied. The influence of phase orientation on the critical micelle concentration has also been investigated. The results indicate that the critical micelle concentration is lower when the surfactant is added into the continuous phase than when it is added into the dispersed phase. The second system is formed by two immiscible liquids, hexadecane and water. In measuring the dynamic IFT of this system, the effect of phase orientation is found to be similar to the first system. It is found that both the ready-made and in situ-formed surfactants can decrease the IFT between oleic phase and aqueous phase, however, the in situ-formed surfactant is apparently more effective in reducing IFT than the ready-made surfactant. (Abstract shortened by UMI.)
ФОТОГРАФИЧЕСКОЕ ИЗОБРАЖЕНИЕ КАК ФОРМА ПРИНЯТИЯ СОЦИАЛЬНОЙ РЕАЛЬНОСТИ
Creators: name: Ганжара Ольга Анатольевна
Publisher: name: Медиасреда
Year: 2020
Subjects: визуальный объект
фотографическое изображение
социальная идентификация.

description: Изображение человеческого тела, человека в социальной роли в фотографическом изображении – это художественно оформленный объект, метафора, формирование и оформление которой – результат специальной социальной деятельности. Содержательный компонент нормативной логической организации визуального текстового пространства в портретной фотографии формирует новое означаемое, понимание которого происходит только вследствие социальной деструкции текста, снятия плана этически допустимого в конкретной эпистемологической среде повествования.
СРАВНИТЕЛЬНАЯ ХАРАКТЕРИСТИКА ТОК-ШОУ «АНДРЕЙ МАЛАХОВ. ПРЯМОЙ ЭФИР» И «СУДЬБА ЧЕЛОВЕКА С БОРИСОМ КОРЧЕВНИКОВЫМ»
Creators: name: Динмухаметова Диана Данировна
Publisher: name: Медиасреда
Year: 2020
Subjects: ток-шоу
сравнение
Андрей Малахов
Борис Корчевников

description: Данная статья посвящена сравнительной характеристике двух ток-шоу: «Андрей. Малахов. Прямой эфир» и «Судьба человека с Борисом Корчевниковым», а также выявлению жанровых и форматных разнообразий. Работа заключается в детальном разборе и сравнительном анализе двух популярных программ жанра ток-шоу на российском телевиденье.
Temporal divergence of changes in pain and pain-free grip strength after manual acupuncture or electroacupuncture: an experimental study in people with lateral epicondylalgia
Creators: name: Jeon, Jaewon
name: Bussin, Erin
name: Scott, Alexander
Publisher: name: BioMed Central
Year: 2017

description: Background: The objective of this study was to examine, in individuals with lateral epicondylalgia (LE), the acute time course of acupuncture-induced hypoalgesia and change in pain-free grip strength (PFGS). Methods: This was an experimental study, conducted at a single research center in Vancouver, BC. Twenty-one participants with unilateral LE lasting more than 6 weeks duration were enrolled. Participants received a single treatment of acupuncture (either electroacupuncture, 10–30 Hz, or manual acupuncture, assigned randomly). The primary outcome measure was pain level (0–10) during tendon loading (while making a fist) immediately after treatment, and over a 72 h follow-up period. Secondary outcome measures included pain-free grip strength (N). Results: There was a small but statistically significant reduction in participants’ perceived pain level immediately after acupuncture (mean improvement of 1.2, 95% CI 0.45–1.9). This change in pain was not accompanied by a change in PFGS. No difference was observed between the two types of acupuncture at any time point. Conclusions: The use of acupuncture or electroacupuncture, as administered in the current study, is unlikely to acutely enhance the ability of people with LE to engage in pain-free rehabilitation exercise. Trial registration Registered February 25, 2015. ISRCTN14667535, http://www.isrctn.com/ISRCTN14667535
The Role of Digital Finance Embedded in Green Agricultural Development: Evidence from Agribusiness Enterprises in China
Creators: name: Qi, Jiaguo
name: Song, Yan
name: He, Lu
name: Jiang, Minghui
name: Zhou, Lunzheng
Publisher: name: Multidisciplinary Digital Publishing Institute (MDPI)
Year: 2024

description: Digital inclusive agriculture refers to an agricultural development model that integrates various digital technologies into the agricultural production process, aiming to deliver benefits for all stakeholders throughout the agricultural value chain. This paper draws on the ecological symbiosis theory, embeds the concepts of digital finance and social responsibility into the goal of green development in agriculture, selects 395 agribusiness enterprises in China from 2013 to 2022 as the analysis sample, and examines the impact by adopting an improved weighted least squares (WLS) fixed effects model. Results show that digital finance has a significant effect on the quantity and quality of green innovation in agribusiness enterprises, and good social responsibility performance can enhance the innovation promotion effect of digital finance. Heterogeneity analysis reveals that agribusiness belonging to the processing and distribution type, located in the eastern region, and in the growth stage benefit more clearly. This paper provides theoretical references and practical guidelines for solving agricultural financing problems, boosting their green innovation capacity in the digital age. It is of great practical significance for realizing the green symbiotic ecology of responsible agricultural industry, promoting the win–win situation between enterprises and society, and the high-quality development of agriculture.
Investigation into the effector repertoire of the H2 type VI secretion system of Pseudomonas aeruginosa
Creators: name: Wood, Thomas Edgar
Publisher: name: Imperial College London
Year: 2018

description: Pseudomonas aeruginosa is an opportunistic pathogen, causing both acute and chronic infections. This bacterium displays remarkable adaptability and potential for virulence, partly due to its arsenal of protein secretion systems. The type VI secretion system (T6SS) is a contractile injection apparatus, firing a spear-like structure into target cells to deliver its cargo of effector proteins. P. aeruginosa encodes three such systems, denoted H1-, H2- and H3-T6SS. This dissertation discloses work focused on progressing our understanding of the H2-T6SS in this pathogen. We reveal that the H2-T6SS is controlled by the Gac/Rsm pathway, a major regulatory network in this pathogen responsible for the lifestyle switch between motile and sessile bacteria. Quorum sensing, the sophisticated signalling network governing social behaviour, is responsible for the expression of this secretion system in a growth-phase dependent manner, while temperature also has an input in a strain-dependent fashion. We advance our understanding of the composition of the H2-T6SS nanomachine, identifying multiple components of the spear-like delivery device, comprising an Hcp tube capped with a spike structure composed of three VgrGs and one PAAR protein. Importantly, we begin to decipher the payload of this secretion system, describing several phospholipase family effectors which confer a significant advantage to P. aeruginosa during bacterial competition. Building upon this, we propose a hierarchy of effector delivery determined by the VgrG/PAAR composition of the spike. Finally, we characterise a specific H2-T6SS effector: the C-terminal extension of the VgrG2b spike protein. Although we initially investigate its reported role within eukaryotic cells, we determine that this metallopeptidase-like effector is part of a wider antibacterial T6SS toxin family. We describe its cognate periplasmic immunity determinant and progress the elucidation of the target of the effector. Overall, we advance our understanding of the H2-T6SS of P. aeruginosa in terms of its regulation, organisation and cargo.
An interpretative-theoretical model of ethical decision-making for sport organizations.
Creators: name: Malloy, David Cruise.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Business Administration, General.

description: The purpose of this study is to develop a model of ethical decision making which will provide a generic and comprehensive philosophical and psychological theoretical foundation for the extension of current theoretical knowledge of ethical behaviour in organizations. In addition, the study's purpose is to provide information which might enhance the practitioner's ability to make ethically right, good, and authentic decisions. The primary data for the study are 14 theoretical models of ethical decision making developed in or having relevance ot administrative contexts. The study employs an interpretative-theoretical methodology of model construction which is both rigorous and deliberative. This methodology consists of four sequential phases: exploration, analysis, classification, and explanation. The five questions posed are as follows: (1) What is the purpose of ethical decision making? (2) What are the theoretical foundations of ethical decision making? (3) What are the elements of ethical decision making? (4) What are the moderators of ethical decision making? (5) What is the process of ethical decision making? The study concludes that there are two general purposes of ethical decision making in administrative contexts, member utility and organizational utility. Member utility refers to the enhanced effectiveness of organizational members who are able to avoid ethical transgression; organizational utility refers to the general enhancement of the organization in terms of efficiency and effectiveness as mediated through the organizational culture and climate. The theoretical foundations for ethical decision making are philosophical and psychological. Seven elements of ethical decision making are identified in the model. These elements are the recognition of the ethical issue, alternative generation, ethical evaluation of the alternatives, ethical judgement, intention, overt ethical/unethical behaviour, and ethical evaluation of behaviour. The moderators of ethical decision making are eclectic and have been grouped into five distinct categories of influencing variables. They are: individual, issue specific, significant other, situational, and external moderators. The moderators influence the decision maker and the ethical decision-making process. The model proposes that the process that ought to be employed by decision makers is open and rational. (Abstract shortened by UMI.)
Modelling and engineering anabaena sp. PCC 7120 for nitrogen excretion
Creators: name: Malatinszky, David
Publisher: name: Imperial College London
Year: 2017

description: Nitrogen is an essential element for every organism on Earth. Modern agricultural activity depletes soil in nitrogen much faster than it is naturally replenished. Therefore, fertilization is key for feeding a fast-growing population. However, the use efficiency of fertilizer nitrogen is only about 60%. The rest of reactive nitrogen leaches to the environment, and the pollution caused demands modern societies tens of billions of euros annually as remediation costs. Rationalisation of current agricultural practices is essential, including a more targeted application of fertilizers, to tackle the nitrogen crisis. One way is the use of nitrogen-fixing organisms as biofertilizer in close association to agricultural crops. In this thesis, a stoichiometric model was reconstructed for the heterocystous nitrogen-fixing cyanobacterium Anabaena sp. PCC 7120 to understand the nature of metabolite exchange between its photosynthetic and diazotrophic cell types, and design metabolic engineering strategies for nitrogen excretion. Using flux balance analysis of diazotrophically grown filaments, excretion of ammonia followed by urea achieved the highest molar nitrogen flux. To achieve a similar effect experimentally, glutamine synthetase (GS) was inhibited using L-methionine sulfoximine. It was possible to accumulate about 760 μM ammonia in a 7-day assay with stagnating growth. For stable excretion, GS has been replaced for an active-site mutant exhibiting decreased specific activity for ammonia. The metabolic changes have been implemented in both wild type and an ammonium uptake transporter mutant (Δamt). The resulting strains displayed increased ammonia excretion up to about 8-fold compared to the wild type. Furthermore, IF7A, a small oligopeptide controlling the activity of GS, has been overexpressed under four different promoters. The constructs driven by two of these promoters, PnifHDK and PpetE enabled the growth of the non-diazotrophic alga Chlorella vulgaris at 68% of that of the algal monoculture on combined nitrogen. Overall, the ammonia-excreting strains provided an important proof-of-principle for the development of more efficient biofertilizers in future agriculture.
Cisplatin-induced cytotoxicity in MDCK cells.
Creators: name: Li, Yan Julia.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Health Sciences, Pharmacology.

description: Background. The mechanism of cisplatin-induced nephrotoxicity is not well understood. The distal tubules are affected in both human and animal studies, although the majority of cisplatin-induced renal damage is in proximal tubules. Platinum (Pt) forms intra- and interstrand cross-links with DNA in cancer cells. Hypothesis. A mechanism of cisplatin-induced cytotoxicity in MDCK cells relates to its ability to bind to DNA and interfere with its synthesis. Methods. The canine distal renal tubular epithelial cell line, MDCK was used as an in vitro model to investigate the mechanism of cisplatin-induced nephrotoxicity. The intracellular Pt accumulation and Pt binding with DNA were assayed by atomic absorption spectrophotometry. DNA synthesis was measured by BrdU labeling and fluorescence microscopy at the concentrations from 0 to 100 muM. The alkaline comet assay with 10 Gy radiation was used to measure Pt DNA interstrand cross-links after a one hour cisplatin exposure from 0 to 100 muM at both zero and sixteen hour time points. According to the principles of alkaline comet assay, the tail moment is inversely related with the amount of Pt interstrand cross-links. (Abstract shortened by UMI.)
The kernel and shell structure as a tool for improving the graph of transportation connections
Creators: name: MAŻBIC-KULMA, Barbara
name: OWSIŃSKI, Jan W.
name: SĘP, Krzysztof
name: STAŃCZAK,
Publisher: name: Wrocław University of Technology, Wrocław University of Economics, Polish Operational and Systems Research Society
Year: 2013
Subjects: transport, connections graph, hub and spoke, kernel and shell, α-clique, genetic algorithm

description: OPERATIONS RESEARCH AND DECISIONS; ISSN 2081-8858
The Professional Pathway for International Genetic Counseling Students in the United States
Creators: name: Klopfenstein, Kiera
Publisher: name: Brandeis University
Year: 2023
Subjects: genetic counseling
genetic counseling training program
international genetic counseling
international genetic counseling student
job search
program experience

description: Since the start of the genetic counseling profession in 1969, the field has continued to expand both in the U.S. and globally. International students choose to attend U.S. genetic counseling (GC) programs for various reasons, but limited research has been conducted on their experiences. This study aimed to better understand why international GC students chose to study in the U.S., their experiences with the application process and training, and their goals and path post-graduation. Forty-five current international GC students and graduates that attended U.S.-based genetic counseling programs participated in our anonymous, online survey. The top reasons participants chose to apply to a U.S. GC program were limited/no training in their country of citizenship (80%), the competitive application process in their country of citizenship (55.6%), & the ability to use a genetic counseling degree from the U.S. abroad (48.9%). More than 50% of respondents said that cultural factors, such as nondirectiveness, patient autonomy, preparation requirements prior to clinic, social expectations of the healthcare environment, and training, education levels, and roles of allied healthcare providers, were easy or very easy to understand and adapt. However, many mentioned challenges including: a lack of resources on how to navigate U.S. systems to get established after arriving (e.g., navigating banking, healthcare, housing) (66.7%), securing sufficient funding (44.4%), lack of support obtaining a visa or lack of information about the visa process (44.4%), and feeling like an outsider due to nationality, accent, etc. (38.9%). There was a significant difference in the ideal post-graduation job location at the beginning of their program between Canadian and non-Canadian respondents (p=<0.001), with more Canadian respondents indicating a desire to work in their country of citizenship, likely due to the availability of more jobs. Our study found a desire for more support/resources on getting established in the U.S. and adjusting to U.S. GC programs, and more mentorship and advice from previous or current international students throughout the international genetic counseling student experience. Genetic counseling programs should consider increasing mentorship opportunities and logistical support to improve the experiences of international GC students overall.
Modelling a highly biased random walk: Application to gel electrophoresis
Creators: name: Gauthier, Michel
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Physics, General.

description: The drift and diffusion motions of biased particles are commonly studied using random walks on lattices. We present a novel theoretical approach that makes it possible to calculate exact mobilities in the presence of lattice obstacles. Several two-dimensional examples are studied and a particular attention is given to separation techniques and how our model can be used to study such devices. We also broach the problems related to the field-dependence of the diffusion coefficient during random walks, and we present new algorithms that remove these difficulties. We develop new Monte Carlo algorithms that make it possible to study both drift and diffusion processes simultaneously, even in presence of very strong fields. Finally, we present two brief discussions about the addition of curved field lines and viscosity gradients to our lattice models. This work opens the door to a wide range of applications, especially for the study of electrophoretic technologies.
title: Impact of surgical management in cases of intraoperative membrane perforation during a sinus lift procedure
title: a follow-up on bone graft stability and implant success
titleType: Subtitle
Creators: name: Beck-Broichsitter, Benedicta E.
name: Westhoff, Dorothea
name: Behrens, Eleonore
name: Wiltfang, Jorg
name: Becker, Stephan T.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: Sinus floor elevation
subject: Intraoperative complication
subject: Perforation
subject: Schneiderian membrane
subject: Implant surviva
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Until now, sinus floor elevation represents the gold standard procedure in the atrophic maxilla in order to facilitate dental implant insertion. Although the procedure remains highly predictive, the perforation of the Schneiderian membrane might compromise the stability of the augmented bone and implant success due to chronic sinus infection. The aim of this retrospective cohort study was to show that a membrane tear, if detected and surgically properly addressed, has no influence on the survival of dental implants and bone resorption in the augmented area. Methods Thirty-one patients with 39 perforations could be included in this evaluation, and a control group of 32 patients with 40 sinus lift procedures without complications were compared regarding the radiographically determined development of bone level, peri-implant infection, and implant loss. Results Implant survival was 98.9% in the perforation group over an observation period of 2.7 (± 2.03) years compared to 100% in the control group after 1.8 (± 1.57) years. The residual bone level was significantly lower in the perforation group (p = 0.05) but showed no difference direct postoperatively (p = 0.7851) or in the follow-up assessment (p = 0.2338). Bone resorption remained not different between both groups (p = 0.945). A two-stage procedure was more frequent in the perforation group (p = 0.0003) as well as peri-implantitis (p = 0.0004). Conclusions Within the limits of our study, the perforation of the Schneiderian membrane did not have a negative impact on long-term graft stability or the overall implant survival.
A Maya Landscape Legacy: Analysis of Settlement Patterns of the Classic Period Maya in the Santo Domingo-Lacanja Valley
Creators: name: Bazarsky, Alexandra Faith
Publisher: name: Brandeis University
Year: 2023
Subjects: Ancient Maya
GIS
settlement patterns
landscape
Lidar
Archaeology
Remote Sensing

description: This thesis presents the findings derived from satellite and high-resolution airborne lidar data of the Upper Usumacinta River basin of Mexico and Guatemala. Multiple environmental and spatial models were made from the remotely sensed data to look at the settlement patterns between the Classic period (250-900 A.D.) kingdoms centered on the sites of La Mar and Lacanja Tzeltal. ArcGIS Pro tools such as Stream Order, Basin, Least Cost Path, Kernel Density Estimation, and Geomorphon Landforms were used to define what factors most impacted the Maya’s preference for living in certain areas. The results establish that both environmental and socio-political factors heavily impacted ancient settlement preference. More broadly, this research emphasizes the strengths of remote sensing and GIS technology within archaeological study of settlement patterns, and it serves as a foundation for future studies to draw further connections between the relationships of landscape, politics, agriculture, the economy, and social organization.
A numerical model for char combustion in packed bed reactors.
Creators: name: Cooper, Judy.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1996
Subjects: subject: Engineering, Chemical.

description: A numerical simulation of the combustion of centimeter-sized char particles in an overfeed fuel bed is presented. One-dimensional mass, species and energy balances for the reading system are solved by finite volume discretization methods to predict operating curves and temperature and concentration profiles for char combustion under a variety of conditions. The simulation is unique in that it employs separate gas and solid phase energy balances with finite-rate CO kinetics and a particle number balance to account for the shrinkage of the char particles as they descend through the bed. All the major energy transport processes, such as particle-to-fluid heat and mass transfer, conduction, convection and radiation, are modelled. The simulation was run for beds of 1-3 cm particles ranging from 30-60 cm in height. The range of air flow rates studied ranged from 0.036 to 0.87 m/s. Comparisons between predicted gas and temperature profiles and similar profiles obtained from the literature generally showed good agreement, indicating that the simulation was reliable enough for use as a design tool over the range of conditions that were studied. The simulation proved to be quite sensitive to choices of the heat and mass transfer coefficients and also to the CO$\sb2$ reduction rate expression, indicating that there is a need for more research on large-particle kinetics and high-temperature packed bed energy transport processes.
Moving up the learning curve: The digital electronic revolution in Canada, 1945-1970.
Creators: name: Vardalas, John Nicholas.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: History, Canadian.

description: In the decades immediately following World War II, a new constellation of technologies and industries emerged as powerful engines of global economic development. A nation's capacity to innovate on the frontiers of digital electronic technology became a crucial measure of its techno-economic development. During the formative years 1945-1970 the major industrialized nations of the world scrambled to assert a domestic design and manufacturing competence within the digital electronic paradigm. The scramblers included Canada. Through a series of six case studies, this thesis presents the first fine-grained view of Canada's efforts to jump on the nascent, global, digital electronic wave. At the heart of the narrative is the historical process that created Canada's first "community" of digital technologists. The salient features of Canada's ascent of the learning curve associated with digital technologies are the unprecedented role of military enterprise in the creation of a peacetime pool of scientific and technical skills in industry and in government defence laboratories; the smaller, sometimes erratic, but nevertheless important role of civilian public enterprise in nurturing industrial learning after the military's retreat; the surprising contribution of branch plants to fostering indigenous technical knowledge accumulation and skill acquisition at the very frontiers of technical change; and the ability of this newly created pool of expertise, in its design decisions, to refract the global, digital innovation wave through the Canadian context.
Using a natural language processing toolkit to classify electronic health records by psychiatric diagnosis
Creators: name: Hutto, Alissa
name: Zikry, Tarek M
name: Cheever, C Ray
name: Nash, Rebekah P.
name: Bohac, Buck
name: Staebler, Jasmine
name: Slay, Janet
name: Kosorok, Michael R
name: Rose, Terra
Publisher: name: SAGE Publications
Year: 2024

description: Objective: We analyzed a natural language processing (NLP) toolkit’s ability to classify unstructured EHR data by psychiatric diagnosis. Expertise can be a barrier to using NLP. We employed an NLP toolkit (CLARK) created to support studies led by investigators with a range of informatics knowledge. Methods: The EHR of 652 patients were manually reviewed to establish Depression and Substance Use Disorder (SUD) labeled datasets, which were split into training and evaluation datasets. We used CLARK to train depression and SUD classification models using training datasets; model performance was analyzed against evaluation datasets. Results: The depression model accurately classified 69% of records (sensitivity = 0.68, specificity = 0.70, F1 = 0.68). The SUD model accurately classified 84% of records (sensitivity = 0.56, specificity = 0.92, F1 = 0.57). Conclusion: The depression model performed a more balanced job, while the SUD model’s high specificity was paired with a low sensitivity. NLP applications may be especially helpful when combined with a confidence threshold for manual review.
ИСТОРИЯ ЖУРНАЛИСТИКИ
Creators: name: Егоркина Елена Юрьевна
Publisher: name: Медиасреда
Year: 2020
Subjects: журналистика
пражурналистика
СМИ
Интернет.

description: Кратко представлена обобщенная история журналистики как профессиональной деятельности. Рассмотрены основные вехи развития журналистики, включающие в себя создание книгопечатания, радио, телевидения и Интернета. Проанализирован путь ее развития от пражурналистики к современной журналистике. Выявлены особенности в истории развития журналистики, связанные с техническим развитием.
Key Challenges in the Search for Innovative Drug Treatments for Special Populations. Converging Needs in Neonatology, Pediatrics, and Medical Genetics
Creators: name: MacLeod, Stuart
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: The explosion of knowledge concerning the interplay of genetic and environmental factors determining pathophysiology and guiding therapeutic choice has altered the landscape in pediatric clinical pharmacology and pharmacy. The need for innovative research methods and design expertise for small clinical trials to be undertaken in sparse populations has been accentuated. At the same time, shortfalls in critical human resources represent a key challenge, especially in low- and middle-income countries where the need for new research and education directions is greatest. Unless a specific action plan is urgently developed, there will be a continuing gap in availability of the essential expertise needed to address treatment challenges in special patient populations such as neonates, patients suffering from rare or neglected diseases, and children of all ages.
Hyperbolic metric spaces, their boundaries, and north-south dynamics
Creators: name: Dias, III, Andrew Clement
Publisher: name: Brandeis University
Year: 2024
Subjects: boundary
geometric group theory
hyperbolic group
hyperbolic space
isometry
north-south dynamics

description: In this thesis, we aim to study dynamics on the boundary of hyperbolic spaces and hyperbolic groups induced by isometries of these spaces. In particular, we focus on north-south dynamics induced by loxodromic isometries. Much of this thesis covers background material in the area of hyperbolic spaces and hyperbolic groups with Chapter 2 covering the definition of hyperbolic spaces along with properties of these spaces. We also describe the behavior of quasi-geodesics in hyperbolic space, the important Morse lemma, and the quasi-isometric invariance of hyperbolicity. In Chapter 3, we discuss a number of constructions for the boundary of a hyperbolic space and show their equivalence. We then define a topology on the boundary, noting that the boundary is compact under this topology and that quasi-isometries of hyperbolic space extend to homeomorphisms on its boundary. This boundary is a metrizable space and so we then use methods by Bourbaki as well as Ghys and de la Harpe to construct a well-defined metric on the boundary of hyperbolic space. We finish the chapter with a cursory introduction to hyperbolic groups, their boundaries, and actions of a group on hyperbolic space. Chapter 4 covers isometries of hyperbolic spaces and includes the classification of these isometries. A contribution of this thesis is to combine disparate definitions for each class of isometry and prove their equivalence. In Chapter 5, we introduce the force of an isometry along with a new metric on the boundary of hyperbolic space, allowing us to utilize tools that use points in the boundary as a reference rather than points in the space itself. We then reclassify the isometries of hyperbolic space with respect to the force of the isometry and, in another contribution of the thesis, prove that these new definitions are equivalent to the previous ones. While the phenomenon of north-south dynamics is well-referenced in literature, a complete proof is not readily accessible and this is the main goal of this thesis. So lastly, we reference results from Solomon Leader to offer a complete and rigorous proof of north-south dynamics.
Kitsap County 4-H Newsletter, August 2020
Creators: name: Washington State University Kitsap County Extension
Publisher: name: Washington State University
Year: 2020
Subjects: 4-H Club

description: Contents:
description: Important Dates
description: In the Spotlight
description: 4-H in Kitsap County
description: State & National 4-H Opportunities
description: 4-H Fundraisers
description: Scholarship Opportunities
description: Volunteer News
description: 4-H Office Contact Information
Predicting the ice clearing capacity of Lac St-Pierre.
Creators: name: Morin, Isabelle.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Engineering, Civil.

description: Lac St-Pierre is particularly prone to ice jams that create difficult conditions for navigation on the shipping channel. In this project, a mathematical model was used to determine the ice clearing on Lac St-Pierre under various conditions. The particle-dynamics model Pdyn was applied to simulate a wide range of channel configurations and ambient environmental conditions. Relationships between ice movement and ambient conditions were then developed by aggregating the results from a large number of simulations. The relationships obtained quantify the relative impact of various parameters, such as the channel geometry, floe size, ice concentration, and wind, on ice velocity and flux. And since it makes use of readily measurable field data, the mathematical model is particularly valuable for inclusion into an integrated ice management system.
ОСОБЕННОСТИ ВИЗУАЛИЗАЦИИ ИНФОРМАЦИИ В ПАБЛИКЕ «ЖУРФАК ЧЕЛГУ ВКОНТАКТЕ»
Creators: name: Ивандаева Елизавета Константиновна
Publisher: name: Медиасреда
Year: 2020
Subjects: визуализация информации
дизайн
ВКонтакте
мем
фотография

description: Внешний вид постов в социальных сетях сейчас имеет не меньшее значение, чем их внутреннее содержание. Поэтому необходимо детально изучать каждый способ визуализации, опираясь на мнения экспертов-дизайнеров. В статье мы рассмотрим критерии успешной визуализации, а также являются ли посты в паблике «Журфак ЧелГУ» соцсети ВКонтакте удачными с дизайнерской точки зрения.
The effect of wearing work boots on lumbar spine flexion.
Creators: name: Blench, Michael Anthony.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Health Sciences, Occupational Health and Safety.

description: The unilateral muscle activity of the erector spinae muscles, hip extensors, knee extensors, ankle dorsiflexors and plantarflexors, along with joint articulation kinematics of the ankle, knee, hip and lumbar region in the sagittal plane, were examined as' a multi-link system. The objective was to determine the effects of wearing work boots on joint kinematics with particular emphasis on the lumbar angle formed by the spinous processes of S3-L3-T10. Seventeen male subjects volunteered to perform specific 'repeated measures' exercises of a material handling nature while wearing properly laced work boots and barefoot with the feet on boot wedges but in an unbound state. Differences in relative angles, and EMG magnitude and timing were examined. The results of this study demonstrate that by externally restricting the articulation of the ankle-foot complex, other joints of the body compensate. If the restriction is in place for the most part, potentially, derogatory side effects could result such as back problems and the low back could become more susceptible to injury. Any research identifying other etiological factors that could be contributing to back pain or injury is very relevant. (Abstract shortened by UMI.)