cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Silicon enhances suberization and lignification in roots of rice (Oryza sativa)
Creators: name: Fleck, Alexander T.
name: Nye, Thandar
name: Repenning, Cornelia
name: Stahl, Frank
name: Zahn, Marc
name: Schenk, Manfred K.
Publisher: name: Oxford : Oxford University Press
Year: 2011
Subjects: subject: exodermis
subject: leucine-rich repeat protein (LRR)
subject: lignin radial oxygen loss (ROL)
subject: Oryza sativa (rice)
subject: silicic acid silicon
subject: suberin
subject: lignin
subject: lipid
subject: silicic acid
subject: silicon
subject: article
subject: gene expression profiling
subject: gene expression regulation
subject: growth, development and aging
subject: metabolism
subject: oxidation reduction reaction
subject: physiology
subject: plant root
subject: rice
subject: Gene Expression Profiling
subject: Gene Expression Regulation, Plant
subject: Lignin
subject: Lipids
subject: Oryza sativa
subject: Oxidation-Reduction
subject: Plant Roots
subject: Silicic Acid
subject: Silicon
subject: Dewey Decimal Classification::500 | Naturwissenschaften::580 | Pflanzen (Botanik)

description: The beneficial element silicon (Si) may affect radial oxygen loss (ROL) of rice roots depending on suberization of the exodermis and lignification of sclerenchyma. Thus, the effect of Si nutrition on the oxidation power of rice roots, suberization and lignification was examined. In addition, Si-induced alterations of the transcript levels of 265 genes related to suberin and lignin synthesis were studied by custom-made microarray and quantitative Real Time-PCR. Without Si supply, the oxidation zone of 12 cm long adventitious roots extended along the entire root length but with Si supply the oxidation zone was restricted to 5 cm behind the root tip. This pattern coincided with enhanced suberization of the exodermis and lignification of sclerenchyma by Si supply. Suberization of the exodermis started, with and without Si supply, at 4-5 cm and 8-9 cm distance from the root tip (drt), respectively. Si significantly increased transcript abundance of 12 genes, while two genes had a reduced transcript level. A gene coding for a leucine-rich repeat protein exhibited a 25-fold higher transcript level with Si nutrition. Physiological, histochemical, and molecular-biological data showing that Si has an active impact on rice root anatomy and gene transcription is presented here.
Protostellar Disk Formation Enabled by Weak, Misaligned Magnetic Fields
Creators: name: Krumholz, Mark R.
name: Crutcher, Richard M.
name: Hull, Charles L. H.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The gas from which stars form is magnetized, and strong magnetic fields can efficiently transport angular momentum. Most theoretical models of this phenomenon find that it should prevent formation of large (>100 AU), rotationally-supported disks around most protostars, even when non-ideal magnetohydrodynamic (MHD) effects that allow the field and gas to decouple are taken into account. Using recent observations of magnetic field strengths and orientations in protostellar cores, we show that this conclusion is incorrect. The distribution of magnetic field strengths is very broad, and alignments between fields and angular momentum vectors within protostellar cores are essentially random. By combining the field strength and misalignment data with MHD simulations showing that disk formation is expected for both weak and misaligned fields, we show that these observations imply that we should expect disk fractions of ~10 - 50% even when protostars are still deeply embedded in their parent cores, and even if the gas is governed by ideal MHD.
description: 4 pages, 2 figures, emulatedapj format, submitted to ApJL
A new perspective on nonholonomic brackets and Hamilton-Jacobi theory
Creators: name: de León, Manuel
name: Lainz, Manuel
name: López-Gordón, Asier
name: Marrero, Juan Carlos
Publisher: name: arXiv
Year: 2023
Subjects: subject: Mathematical Physics (math-ph)
subject: Differential Geometry (math.DG)
subject: Dynamical Systems (math.DS)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: primary: 37J60, 70F25, 70H20, secondary: 53D17, 53Z05, 70G45

description: The nonholonomic dynamics can be described by the so-called nonholonomic bracket on the constrained submanifold, which is a non-integrable modification of the Poisson bracket of the ambient space, in this case, of the canonical bracket on the cotangent bundle of the configuration manifold. On the other hand, another bracket, also called nonholonomic bracket, was defined using the description of the problem in terms of skew-symmetric algebroids. Recently, reviewing two older papers by R. J. Eden, we have defined a new bracket which we call Eden bracket. In the present paper, we prove that these three brackets coincide. Moreover, the description of the nonholonomic bracket à la Eden has allowed us to make important advances in the study of Hamilton-Jacobi theory and the quantization of nonholonomic systems.
description: 36 pages, no figures. Final version appearing the journal
Fabrication and transport properties of Sr0.6K0.4Fe2As2 multifilamentary superconducting wires
Creators: name: Yao, Chao
name: Ma, Yanwei
name: Wang, Chengduo
name: Zhang, Xianping
name: Wang, Dongliang
name: Wang, Chunlei
name: Lin, He
name: Zhang, Qianjun
Publisher: name: arXiv
Year: 2012
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Seven-core Ag/Fe sheathed Sr0.6K0.4Fe2As2 (Sr-122) superconducting wires were produced by the ex situ powder-in-tube (PIT) method. The relationship between the cold-work deformation process and the superconducting properties of wires were systematically studied. It was found that flat rolling can efficiently increase the density of the superconducting core and largely improve the transport critical current density (Jc) of as-drawn wires. The Jc of the best sample achieved 21.1 kA/cm^2 at 4.2 K in self field, and showed very weak magnetic field dependence in high fields. Our result suggested a promising future of multifilamentary iron-based superconductors in practical application.
description: 19 pages, 6 figures
Die römische Moselbrücke bei Coblenz. Bericht über die Ausgrabung und Aufnahme der im Flussbette der Mosel bei Coblenz aufgefundenen Pfahl- und Steinreste
Creators: name: Schmidt, [?]
Publisher: name: Bonner Jahrbücher
Year: 2017

description: [nicht vorhanden / not available]
description: Bonner Jahrbücher, Bd. 42 (1867): Jahrbücher des Vereins von Alterthumsfreunden im Rheinlande
The Solar Spectrum in the Atacama Desert
Creators: name: Cordero, R.R.
name: Damiani, A.
name: Seckmeyer, Gunther
name: Jorquera, J.
name: Caballero, M.
name: Rowe, P.
name: Ferrer, J.
name: Mubarak, Riyad
name: Carrasco, J.
name: Rondanelli, R.
name: Matus, M.
name: Laroze, D.
Publisher: name: London : Macmillan Publishers Limited
Year: 2016
Subjects: subject: Atacama Desert
subject: ozone
subject: Atmospheric chemistry
subject: Atmospheric dynamics
subject: Dewey Decimal Classification::500 | Naturwissenschaften

description: The Atacama Desert has been pointed out as one of the places on earth where the highest surface irradiance may occur. This area is characterized by its high altitude, prevalent cloudless conditions and relatively low columns of ozone and water vapor. Aimed at the characterization of the solar spectrum in the Atacama Desert, we carried out in February-March 2015 ground-based measurements of the spectral irradiance (from the ultraviolet to the near infrared) at seven locations that ranged from the city of Antofagasta (on the southern pacific coastline) to the Chajnantor Plateau (5,100 m altitude). Our spectral measurements allowed us to retrieve the total ozone column, the precipitable water, and the aerosol properties at each location. We found that changes in these parameters, as well as the shorter optical path length at high-altitude locations, lead to significant increases in the surface irradiance with the altitude. Our measurements show that, in the range 0-5100 m altitude, surface irradiance increases with the altitude by about 27% in the infrared range, 6% in the visible range, and 20% in the ultraviolet range. Spectral measurements carried out at the Izana Observatory (Tenerife, Spain), in Hannover (Germany) and in Santiago (Chile), were used for further comparisons.
title: Integrating Cover Crops and Herbicides for Horseweed [Conyza canadensis (L.) Cronq.] Management Prior to Soybean [Glycine max (L.) Merr.]
Creators: name: Sherman, Austin
Publisher: name: University of Kentucky Libraries
Year: 2019

description: Horseweed (Conyza canadensis (L.) Cronq.) is prevalent in Kentucky and can be difficult to control. Research has shown multiple weed control methods to be more sustainable than relying on chemical control alone, so the use of multiple methods for horseweed management was examined in this study. The main objective was to determine best practice(s) to reduce horseweed prior to soybean [Glycine max (L.) Merr.]. Treatments included: fall-planted cover crop [CC; cereal rye (Secale cereale L.) or none], fall-applied herbicide (saflufenacil or none), and spring-applied herbicides (dicamba, 2,4-D ester, or none). We hypothesized horseweed densities would be reduced the most where all factors were combined. Saflufenacil suppressed horseweed densities from application through March, when densities increased due to a lack of competition from other winter weeds. Spring herbicides decreased horseweed densities until soybeans reached V1 in 2017, but in 2018 lost efficacy after CC termination. CC alone resulted in the longest horseweed suppression. The combination of spring herbicides and CC usually reduced horseweed densities to near zero between the CC termination and soybean planting. However, some low densities seen soon after soybean planting could be problematic. Further research must be conducted to determine the best integrated horseweed management system until soybean canopy closure.
description: Copyright © Austin Sherman 2019
description: Funding information: Kentucky Soybean Promotion Board
Large System Analysis of Linear Precoding in MISO Broadcast Channels with Confidential Messages
Creators: name: Geraci, Giovanni
name: Couillet, Romain
name: Yuan, Jinhong
name: Debbah, Merouane
name: Collings, Iain B.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: In this paper, we study the performance of regularized channel inversion (RCI) precoding in large MISO broadcast channels with confidential messages (BCC). We obtain a deterministic approximation for the achievable secrecy sum-rate which is almost surely exact as the number of transmit antennas $M$ and the number of users $K$ grow to infinity in a fixed ratio $β=K/M$. We derive the optimal regularization parameter $ξ$ and the optimal network load $β$ that maximize the per-antenna secrecy sum-rate. We then propose a linear precoder based on RCI and power reduction (RCI-PR) that significantly increases the high-SNR secrecy sum-rate for $1
description: to appear IEEE JSAC 2013
DEVELOPING RHYTHMIC PERCEPTION SKILLS IN STUDENTS WITH DISABILITIES IN GENERAL SECONDARY SCHOOLS
Creators: name: Saydillayeva, Gulzoda
Publisher: name: Zenodo
Year: 2024

description: In this article, I emphasized the development of music perception skills in students with disabilities, supporting the development of creativity skills in the use of instruments and stimulating learning with improved quality, learning and shaping their thinking, learning and development.
Vegetation response to exceptional global warmth during Oceanic Anoxic Event 2
Creators: name: Heimhofer, Ulrich
name: Wucherpfennig, Nina
name: Adatte, Thierry
name: Schouten, Stefan
name: Schneebeli-Hermann, Elke
name: Gardin, Silvia
name: Keller, Gerta
name: Kentsch, Sarah
name: Kujau, Ariane
Publisher: name: London : Nature Publishing Group
Year: 2018
Subjects: subject: angiosperm
subject: article
subject: cell proliferation
subject: cold stress
subject: conifer
subject: cooling
subject: forest
subject: France
subject: heat
subject: nonhuman
subject: radiation
subject: savanna
subject: vegetation
subject: Coniferophyta
subject: Magnoliophyta
subject: Dewey Decimal Classification::500 | Naturwissenschaften::550 | Geowissenschaften

description: The Cenomanian–Turonian Oceanic Anoxic Event (OAE2; ~94.5 million years ago) represents an episode of global-scale marine anoxia and biotic turnover, which corresponds to one of the warmest time intervals in the Phanerozoic. Despite its global significance, information on continental ecosystem response to this greenhouse episode is lacking. Here we present a terrestrial palynological record combined with marine-derived temperature data (TEX86) across an expanded OAE2 section from the Southern Provençal Basin, France. Despite high TEX86-derived temperature estimates reaching up to 38 °C, the continental hinterland did support a diverse vegetation, adapted to persist under elevated temperatures. A transient phase of climatic instability and cooling during OAE2 known as Plenus Cold Event (PCE) is marked by the proliferation of open, savanna-type vegetation rich in angiosperms at the expanse of conifer-dominated forest ecosystems. A rise in early representatives of Normapolles-type pollen during the PCE marks the initial radiation of this important angiosperm group.
Aachener Stadtrechnungen aus dem XIV. Jahrhundert, herausgegeben von J. Laurent, Aachen 1865
Creators: name: Ennen, Leonard
name: Loersch, Hugo
Publisher: name: Bonner Jahrbücher
Year: 2017

description: Rezension zu: Aachener Stadtrechnungen aus dem XIV. Jahrhundert, nach den Stadtarchiv-Urkunden herausgegeben von J. Laurent, Stadtbibliothekar und Archivar. Aachen 1865, Kaatzer 455 S. 8°.
description: Bonner Jahrbücher, Bd. 42 (1867): Jahrbücher des Vereins von Alterthumsfreunden im Rheinlande
Drei römische Inschriften aus Pfünz in Mittelfranken
Creators: name: Olenschlager, [?]
Publisher: name: Bonner Jahrbücher
Year: 2017

description: [nicht vorhanden / not available]
description: Bonner Jahrbücher, Bd. 43 (1867): Jahrbücher des Vereins von Alterthumsfreunden im Rheinlande
Percurso do doente – Doença de Huntington / Patient journey – Huntington's disease
Creators: name: Alves Ferreira, João Miguel
Publisher: name: ERN-RND
Year: 2023

description: ENG
Patient Journeys  are info-graphical overviews that visualize patients' needs in the care of their rare disease. Because Patient Journeys are designed from the patient's perspective, they allow clinicians to effectively address the needs of rare disease patients.
Patient Journeys consider that patients' needs may differ at different stages of the disease – e.g., initial symptoms vs. treatment. They also reflect the patients' personal experiences, which may vary depending on the person, clinic and country.
ERN-RND considers Patient Journeys working documents that patients and clinicians can use together to identify gaps in care and adapt care pathways to better meet the needs of patients living with these conditions. Patient Journeys can therefore be seen as a first step toward systematic patient engagement in the design of care pathways.
In addition, Patient Journeys are a useful resource for patients, families, non-specialist clinicians, and the general public to understand the care needs of patients living with a rare neurological disease.
The Patient Journey for Huntington's disease was developed together with Astri Arnesen, ERN-RND ePAG representative and president of the European Huntington association, and members of the Disease Group 'Chorea and Huntington's disease'.
PT
As Jornadas do Doente são sínteses info-gráficas que visualizam as necessidades dos doentes no tratamento da sua doença rara. Uma vez que as Jornadas do Doente são concebidas a partir da perspetiva do doente, permitem aos médicos responder eficazmente às necessidades das pessoas com doenças raras.
Os Percursos do Doente consideram que as necessidades dos doentes podem ser diferentes em diferentes fases da doença – por exemplo, sintomas iniciais versus tratamento. Também reflectem as experiências pessoais dos doentes, que podem variar consoante a pessoa, a clínica e o país.
A ERN-RND considera que os Percursos dos Doentes são documentos de trabalho que os doentes e os médicos podem utilizar em conjunto para identificar lacunas nos cuidados e adaptar os percursos de cuidados para melhor satisfazer as necessidades dos doentes que vivem com estas doenças. Os Percursos do Doente podem, portanto, ser vistos como um primeiro passo para o envolvimento sistemático dos doentes na conceção dos percursos de cuidados.
Além disso, os Percursos dos Doentes são um recurso útil para os doentes, as famílias, os médicos não especialistas e o público em geral compreenderem as necessidades de cuidados dos doentes que vivem com uma doença neurológica rara.
A Viagem do Doente para a doença de Huntington foi desenvolvida em conjunto com Astri Arnesen, representante do ePAG da ERN-RND e presidente da Associação Europeia de Huntington, e com membros do Grupo de Doenças "Coreias e doença de Huntington".
title: The Rural Landscape as Heritage in Turkey Under Changing Climate // Le Paysage Rural Turque, un Patrimoine Soumis au Changement Climatique
Creators: name: Aktürk, Gul
Publisher: name: University of Massachusetts Amherst
Year: 2019

description: This presentation first explores how past local climate trends in the region have shaped construction and location technologies and lifestyles. Next, on-site investigations such as seasonal photographs of historic buildings, meteorological data, records of flooding and erosion, and interviews with local stakeholders are applied to identify the local vulnerabilities of rural built heritage and landscape.
Amaranthus hybridus
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: P.hybridus (L.) Gärtner, Meyer et Scherb. em. Fritsch (P. avatus Hill, P. officinalis Mönch) Cat. 185 und 427. l: Draversaz ob Vionnaz (J.). - 2: Ob Granois-Saviese (Marietan); La Giete Dele ob Ayent (idem). - 3: Stalden-Eisten (A. Keller).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
title: Sustainability, resiliency and authenticity of rural landscapes. The forced relocation of inhabitants at a port in Terraba Sierpe wetlands, Costa Rica, and the ‘un-ruled’ practices in the abandoned landscape of Penyagolosa mountain, Spain
Creators: name: García-Esparza, Juan A.
name: Sanou, Ofelia
Publisher: name: University of Massachusetts Amherst
Year: 2019

description: The poster presented hereby is intended to establish a lively debate on the eventual interpretation of the dynamics in two specific rural landscapes and how their analysis depends on the ability to appropriately select and assimilate the transformations of the place. The two cases expose potential problems that arise when interpreting and managing these rural landscapes. Interpretations can be ‘colonial’ or ‘indigenous’. These approaches, therefore, aim to question why space is sometimes constructed under ‘conscious’ and ‘unconscious’ interpretations of imaginaries, behaviours, expressions, and adaptations which result in characteristic experimentations and transformations of the rural landscape.
Mavacamten in obstructive hypertrophic cardiomyopathy: a profile of its use
Creators: name: Nie, Tina
name: Syed, Yahiya Y.
Publisher: name: Adis Journals
Year: 2023
Subjects: subject: Medicine
subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Declarations Funding The preparation of this review was not supported by any external funding. Authorship and conflict of interest Tina Nie and Yahiya Syed are salaried employees of Adis International Ltd/Springer Nature and declare no relevant conflicts of interest. All authors contributed to the review and are responsible for the article content. Ethics approval, Consent to participate, Consent for publication, Availability of data and material, Code availability Not applicable. Additional information about this Adis Drug Review can be found here. Abstract Mavacamten (Camzyos®), an oral, once-daily cardiac myosin inhibitor, is an important new option for the treatment of patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM). In the USA, mavacamten is the first approved drug for the treatment of adults with symptomatic New York Heart Association (NYHA) class II–III obstructive HCM to improve functional capacity and symptoms. In a pivotal phase 3 trial in this patient population, mavacamten improved exercise capacity, symptom burden, and left ventricular outflow tract obstruction compared with placebo. Mavacamten was generally well tolerated, with the most common adverse events being dizziness and syncope. Longer-term data up to 84 weeks demonstrated that the efficacy of mavacamten was maintained with no new safety concerns. Mavacamten may increase the risk of heart failure due to systolic dysfunction and therefore, individualized dosage and close monitoring is required. © Springer Nature Switzerland AG 2023
Experimental estimation of quantum discord for polarization qubit and the use of fidelity to assess quantum correlations
Creators: name: Benedetti, Claudia
name: Shurupov, Alexander P.
name: Paris, Matteo G. A.
name: Brida, Giorgio
name: Genovese, Marco
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We address the experimental determination of entropic quantum discord for systems made of a pair of polarization qubits. We compare results from full and partial tomography and found that the two determinations are statistically compatible, with partial tomography leading to a smaller value of discord for depolarized states. Despite the fact that our states are well described, in terms of fidelity, by families of depolarized or phase-damped states, their entropic discord may be largely different from that predicted for these classes of states, such that no reliable estimation procedure beyond tomography may be effectively implemented. Our results, together with the lack of an analytic formula for the entropic discord of a generic two-qubit state, demonstrate that the estimation of quantum discord is an intrinsically noisy procedure. Besides, we question the use of fidelity as a figure of merit to assess quantum correlations.
The effectiveness of poly-(4-vinyl-N-hexylpyridiniumbromide) as an antibacterial implant coating: An in vitro study
Creators: name: Ringenberg, L.
name: Winkel, Andreas
name: Kufelt, O.
name: Behrens, Peter
name: Stiesch, Meike
name: Heuer, W.
Publisher: name: New York, NY : Hindawi Publishing Corporation
Year: 2011
Subjects: subject: dental implants
subject: Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit

description: The clinical success of osseointegrated dental implants depends on the strong attachment of the surrounding hard and soft tissues. Bacterial adhesion on implant surfaces can cause inflammatory reactions and may influence healing and long-term success of dental implants. Promising implant coatings should minimize bacterial adhesion, but allow epithelial and connective tissue attachment. Therefore, the present study has examined the bioactive effect of poly-(4-vinyl-N-hexylpyridiniumbromide) regarding typical oral bacteria as well as cytotoxicitiy to human cells considering different methods of connecting polymers to silicate-containing surfaces. The results revealed that the application of putative antibacterial and biocompatible polymer in coating strategies is affected by a variety of parameters. Published findings regarding reduced bacterial adhesion could not be verified using oral pathogens whereas hexylated polymers seem problematic for strong adhesion of soft tissue. Concerning innovative coatings for dental implants basic aspects (surface roughness, thickness, alkylation, combination with other polymers) have to be considered in further investigations.
Seven-Year Multi-Color Optical Monitoring of BL Lacertae Object S5 0716+714
Creators: name: Dai, Yan
name: Wu, Jianghua
name: Zhu, Zong-Hong
name: Zhou, Xu
name: Ma, Jun
name: Yuan, Qirong
name: Wang, Lingzhi
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We have monitored the BL Lac object S5 0716+714 in five intermediate optical wavebands from 2004 September to 2011 April. Here we present the data that include 8661 measurements which represents one of the largest databases obtained for an object at optical domain. A simple analysis of the data indicates that the object was active in most time, and intraday variability was frequently observed. In total, the object varied by 2.614 magnitudes in the $i$ band. Strong bluer-when-brighter chromatism was observed on long, intermediate, and short timescales.
description: 29 pages, 8 figures
Structure and significance of knowledge networks in two low-tech clusters in poland
Creators: name: Abbasiharofteh, Milad
name: Dyba, Wojciech
Publisher: name: Abingdon : Routledge
Year: 2018
Subjects: subject: Cluster life cycle
subject: Furniture cluster
subject: Knowledge network
subject: Low-tech industry
subject: Social network analysis (SNA)
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie::330 | Wirtschaft
subject: Dewey Decimal Classification::900 | Geschichte und Geografie::910 | Geografie, Reisen

description: The co-location and networking of firms and institutions, also known as clustering, positively influences the innovativeness of firms. The cluster literature provides a single-sided understanding of how clusters function due to an overemphasis in the literature on clusters in high-tech and developed economies at the expense of clusters in low-tech industries in less-developed regions. Applying social network analysis (SNA), this paper studies two furniture clusters in the Wielkopolska region of Poland. The findings demonstrate that: (1) the critical factor is the impact of institutionalization on the mechanisms of knowledge flows, Marshall’s externalities and, in consequence, innovativeness of firms; and (2) the underlining clusters do not show a tendency to build cluster-external linkages, opposing the dominant premise in the cluster literature. In the absence of national and international relations, managers of small and me-dium-sized firms and local institutions are the main sources of novelty for the clusters at the sustaining stage of their life cycle. The findings pave the way for initiatives aiming at creating and developing knowledge networks in lagging and catching-up regions in Europe, particularly those specialized in low-tech sectors. © 2018 The Author(s).
Analytical results from the quantum theory of a single-emitter nanolaser. II
Creators: name: Larionov, Nikolay V.
name: Kolobov, Mikhail I.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Using two equivalent approaches, Heisenberg-Langevin and density operator, we investigate the properties of nanolaser: an incoherently pumped single two-level system interacting with a single-cavity mode of finite finesse. We show that in the case of good-cavity regime the Heisenberg-Langevin approach provides the analytical results for linewidth, amplitude fluctuation spectrum, and intracavity Mandel Q-parameter. In the bad-cavity regime we estimate the frequency at which the peak of relaxation oscillations appears. With the help of the master equation for density operator written in terms of coherent states we obtain approximated expression for Glauber-Sudarshan P function. This solution can be used in the case of good-cavity regime and allows us to investigate in more detail the thresholdless behaviour of the nanolaser. All two approaches are in a very good agreement with each other and numerical simulations.
description: 11 pages, 3 figures
Two new dammarane triterpenoid saponins from the leaves of Cyclocarya paliurus
Creators: name: Li, Shan-Bin
name: Xian, Xiao-Ya
name: Peng, Cai-Feng
name: Chen, Li-Qun
name: Luo, Qin
name: Wang, Li-Sheng
name: Zhou, Xian-Li
name: Liang, Cheng-Qin
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Two undescribed dammarane triterpenoid saponins, cypaliurusides O and P (1 and 2), were isolated from the ethanol extracts of the leaves of Cyclocarya paliurus. Bioactivity assay results showed that compound 1 has potential cytotoxic activities against selected human cancer cell lines in vitro, with IC50 values ranging from 14.55 ± 0.55 to 22.75 ± 1.54 µM. Compound 1 showed better antitumor activity against HepG2 cells with IC50 of 14.55 ± 0.55 µM. In addition, compound 2 showed no obvious antitumor activity.
Employed People Who Work from Home in the Italian Regions
Creators: name: Leogrande, Angelo
Publisher: name: Zenodo
Year: 2023

description: Istat calculates the value of employees who work from home. The variable is defined as the percentage of employed people who have carried out their work from home in the last 4 weeks out of the total number of employed people. The data refers to the period 2018-2022 in the 20 Italian regions.
The cycloaspeptides: Uncovering a new model for methylated nonribosomal peptide biosynthesis
Creators: name: De Mattos-Shipley, Kate M.J.
name: Greco, Claudio
name: Heard, David M.
name: Hough, Gemma
name: Mulholland, Nicholas P.
name: Vincent, Jason L.
name: Micklefield, Jason
name: Simpson, Thomas J.
name: Willis, Christine L.
name: Cox, Russell J.
name: Bailey, Andrew M.
Publisher: name: Cambridge : Royal Society of Chemistry
Year: 2018
Subjects: subject: Agriculture
subject: Amino acids
subject: Biochemistry
subject: Biosynthesis
subject: DNA sequences
subject: Gene encoding
subject: Gene expression
subject: Metabolites
subject: Peptides
subject: Substrates
subject: Agricultural industries
subject: Bioactive pentapeptides
subject: Heterologous expression
subject: Insecticidal activity
subject: N-methylated amino acids
subject: Non-ribosomal peptide biosynthesis
subject: Nonribosomal peptide synthetases
subject: Selective incorporations
subject: Polypeptides
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: The cycloaspeptides are bioactive pentapeptides produced by various filamentous fungi, which have garnered interest from the agricultural industry due to the reported insecticidal activity of the minor metabolite, cycloaspeptide E. Genome sequencing, bioinformatics and heterologous expression confirmed that the cycloaspeptide gene cluster contains a minimal 5-module nonribosomal peptide synthetase (NRPS) and a new type of trans-acting N-methyltransferase (N-MeT). Deletion of the N-MeT encoding gene and subsequent feeding studies determined that two modules of the NRPS preferentially accept and incorporate N-methylated amino acids. This discovery allowed the development of a system with unprecedented control over substrate supply and thus output, both increasing yields of specific metabolites and allowing the production of novel fluorinated analogues. Furthermore, the biosynthetic pathway to ditryptophenaline, another fungal nonribosomal peptide, was shown to be similar, in that methylated phenylalanine is accepted by the ditryptophenaline NRPS. Again, this allowed the directed biosynthesis of a fluorinated analogue, through the feeding of a mutant strain. These discoveries represent a new paradigm for the production of N-methylated cyclic peptides via the selective incorporation of N-methylated free amino acids. © 2018 The Royal Society of Chemistry.
Einführung in das Thema
Creators: name: Haspel, Jörg
name: Winghart, Stefan
Publisher: name: ICOMOS – Hefte des Deutschen Nationalkomitees
Year: 2017

description: ICOMOS – Hefte des Deutschen Nationalkomitees, Bd. 61 (2016): ICOMOS – Hefte des Deutschen Nationalkomitees
title: Between agriculture and delight: villas, gardens and agricultural landscape in northern Italy
Creators: name: Laviscio, Raffaella
name: Scazzosi, Lionella
name: Pelissetti, Laura
name: Lodari, Renata
Publisher: name: University of Massachusetts Amherst
Year: 2019

description: The villa-garden as core of agricultural enterprise spreads in the North of Italy particularly since the second half of the XVII century. Throughout the eighteenth century, there was the flowering of large stately villas that, in addition to villas of delight, are configured as "centers of capitalist investment in the land economy and as centers for reorganization of the agricultural landscape in large rural estates" (Sereni 1961, p.289). Thus, some of the Royal House's Residences in Piemonte also affect the structure of the surrounding land where the gardens and parks became the core of the land shape to improve the agricultural income and hence to promote a modern agricultural management of the estates. Both the Venaria Reale palace, with an agricultural texture of the areas outside the gardens, designed by Juvarra between 1725 and 1730, and the Racconigi Castle, where the new landscape layout designed by Kürten (1820-1832) became the headquarters of the royal farms respectively in the adjacent royal estates of La Mandria (from 1860) and Migliabruna (from 1835). In Lombardy a very particular case is that of the Royal Villa and the park of Monza where, with the project of Canonica in 1808, the agricultural character of Brianza affected the park that was thus surrounded by arable land, vineyards, orchards, mulberry trees, as well as large portions of woodland, used as a hunting reserve (De Giacomi, 1989). The park was laid-out as a self-sufficient farm, while the productive issues affected the architecture of the garden, where optical cones and perspective views were directed to the discovery of the agricultural landscape. The garden and the park also shaped the surrounding agricultural landscape. Many other case studies in northern Italy attest, with different degrees of permanence, the inseparable link between villa, garden and agricultural landscape.
Synthesis of a natural quinoline alkaloid isolated from the deep-sea-derived fungus and its potential as a therapeutic for Parkinson’s disease
Creators: name: Lee, Tae Yeon
name: Yang, Wooin
name: Seok, Dong
name: Han, Young Taek
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: 2-(Quinoline-8-carboxamido)benzoic acid (2-QBA; 1) is a natural quinoline alkaloid isolated from the deep-sea-derived fungus Aspergillus sp. SCSIO06786. Alkaloid 1 was synthesized by an amidation reaction of 8-quinolinecaroxylic acid with methyl anthranilate, followed by hydrolysis. The neuroprotective properties of 1 were evaluated using a Caenorhabditis elegans Parkinson's disease model, which revealed that 1 significantly ameliorated 1-methyl-4-phenylpyridinium (MPP+)-induced dopaminergic neurodegeneration in a dose-dependent manner. MPP+-induced behavioral defects in worms, including impaired locomotion and basal slowing ability, were restored by treatment with 1. We further demonstrated that treatment with 1 modulates the formation of neurotoxic α-synuclein oligomers by suppressing α-synuclein expressions and enhancing proteasome activity. These results suggest that 1 is a promising therapeutic candidate for the treatment of Parkinson’s disease.
Wohin wollen wir? - Architektur und Bauen
Creators: name: Brenncke, Joachim
Publisher: name: ICOMOS – Hefte des Deutschen Nationalkomitees
Year: 2017

description: ICOMOS – Hefte des Deutschen Nationalkomitees, Bd. 61 (2016): ICOMOS – Hefte des Deutschen Nationalkomitees
The unusual afterglow of the Gamma-Ray Burst 100621A
Creators: name: Greiner, J.
name: Krühler, T.
name: Nardini, M.
name: Filgas, R.
name: Moin, A.
name: de Breuck, C.
name: Montenegro-Montes, F.
name: Lundgren, A.
name: Klose, S.
name: Afonso, P. M. J.
name: Bertoldi, F.
name: Elliott, J.
name: Kann, D. A.
name: Knust, F.
name: Menten, K.
name: Guelbenzu, A. Nicuesa
name: E., F. Olivares
name: Rau, A.
name: Rossi, A.
name: Schady, P.
name: Schmidl, S.
name: Siringo, G.
name: Spezzi, L.
name: Sudilovsky, V.
name: Tingay, S. J.
name: Updike, A. C.
name: Wang, Z.
name: Weiss, A.
name: Wieringa, M.
name: Wyrowski, F.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: In order to constrain the broad-band spectral energy distribution of the afterglow of GRB 100621A, dedicated observations were performed in the optical/near-infrared with the 7-channel "Gamma-Ray Burst Optical and Near-infrared Detector" (GROND) at the 2.2m MPG/ESO telescope, in the sub-millimeter band with the large bolometer array LABOCA at APEX, and at radio frequencies with ATCA. Utilizing also Swift X-ray observations, we attempt an interpretation of the observational data within the fireball scenario. The afterglow of GRB 100621A shows a very complex temporal as well as spectral evolution. We identify three different emission components, the most spectacular one causing a sudden intensity jump about one hour after the prompt emission. The spectrum of this component is much steeper than the canonical afterglow. We interpret this component using the prescription of Vlasis et al. (2011) for a two-shell collision after the first shell has been decelerated by the circumburst medium. We use the fireball scenario to derive constraints on the microphysical parameters of the first shell. Long-term energy injection into a narrow jet seems to provide an adequate description. Another noteworthy result is the large ($A_V$ = 3.6 mag) line-of-sight host extinction of the afterglow in an otherwise extremely blue host galaxy.
description: 14 pages, 11 figs; acc. in A&A
Tumor homing and penetrating peptide-conjugated niosomes as multi-drug carriers for tumor-targeted drug delivery
Creators: name: Ag Seleci, Didem
name: Seleci, Muharre,
name: Stahl, Frank
name: Scheper, Thomas
Publisher: name: Cambridge : Royal Society of Chemistry
Year: 2017
Subjects: subject: Cell culture
subject: Dynamic light scattering
subject: Peptides
subject: Spectrum analysis
subject: Stem cells
subject: Tumors
subject: Cellular internalization
subject: Drug delivery system
subject: Human mesenchymal stem cells
subject: Physicochemical property
subject: Synergistic effect
subject: Targeting ligands
subject: Therapeutic agents
subject: Tumor-targeted drug deliveries
subject: Targeted drug delivery
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: The development of nanoscale drug delivery systems, which can mediate efficient tumor targeting together with high cellular internalization, is crucial for glioma treatment. The combination of therapeutic agents in nanoparticles provides synergistic effects and allows further surface modifications with targeting ligands for specific glioma therapy. To achieve this goal, both doxorubicin and curcumin were encapsulated in polyethylene glycolated niosomes (PEGNIO). The surface of co-drug loaded PEGNIO was modified with tumor homing and penetrating peptide (tLyp-1). Physicochemical properties were determined via dynamic light scattering (DLS) and spectral analysis. Moreover, flow cytometry studies were performed to examine the specific cellular uptake of the tLyp-1 targeted niosomal formulation. In vitro cytotoxicity and inhibition of tumor-like spheroids growth were investigated on human glioblastoma (U87) and human mesenchymal stem cells (hMSC) cells. The results clearly indicated that the strategy by co-administration of doxorubicin and curcumin with tLyp-1 functionalized niosomes could significantly improve anti-glioma treatment.
Optical properties of metal-dielectric-metal microcavities in the THz frequency range
Creators: name: Todorov, Yanko
name: Tosetto, Lorenzo
name: Teissier, Jean
name: Andrews, Aaron Maxwell
name: Klang, Pavel
name: Colombelli, Raffaele
name: Sagnes, Isabelle
name: Strasser, Gottfried
name: Sirtori, Carlo
Publisher: name: arXiv
Year: 2012
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We present an experimental and theoretical study of the optical properties of metal-dielectric-metal structures with patterned top metallic surfaces, in the THz frequency range. When the thickness of the dielectric slab is very small with respect to the wavelength, these structures are able to support strongly localized electromagnetic modes, concentrated in the subwavelength metal-metal regions. We provide a detailed analysis of the physical mechanisms which give rise to these photonic modes. Furthermore, our model quantitatively predicts the resonance positions and their coupling to free space photons. We demonstrate that these structures provide an efficient and controllable way to convert the energy of far field propagating waves into near field energy.
Euler-Maruyama approximations of the stochastic heat equation on the sphere
Creators: name: Lang, Annika
name: Motschan-Armen, Ioanna
Publisher: name: arXiv
Year: 2023
Subjects: subject: Numerical Analysis (math.NA)
subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60H35, 65C30, 60H15, 35R60, 33C55, 65M70

description: The stochastic heat equation on the sphere driven by additive isotropic Wiener noise is approximated by a spectral method in space and forward and backward Euler-Maruyama schemes in time. The spectral approximation is based on a truncation of the series expansion with respect to the spherical harmonic functions. Optimal strong convergence rates for a given regularity of the initial condition and driving noise are derived for the Euler-Maruyama methods. Besides strong convergence, convergence of the expectation and second moment is shown, where the approximation of the second moment converges with twice the strong rate. Numerical simulations confirm the theoretical results.
description: Updated convergence plot for the Monte Carlo forward Euler-Maruyama scheme compared to published version
Total synthesis of elansolids B1 and B2
Creators: name: Wang, Liang-Liang
name: Kirschning, Andreas
Publisher: name: Frankfurt am Main : Beilstein-Institut zur Förderung der Chemischen Wissenschaften
Year: 2017
Subjects: subject: Antibiotics
subject: Polyenes
subject: Polyketides
subject: Stille reaction
subject: Suzuki reaction
subject: Total synthesis
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: The elansolids A1–A3, B1, and B2 are secondary metabolites formed by the gliding bacterium Chitinophaga sancti. They show antibacterial activity against Gram-positive bacteria. A second generation total synthesis of the antibiotic elansolid B1 (2) and the first synthesis of elansolid B2 (3) are reported. In contrast to previous work, the (Z,E,Z)-triene at C10–C15 was assembled by using an optimized C–C cross-coupling sequence with a Suzuki cross-coupling reaction as key step.
Sempervivum grandiflorum Lam.
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: D. grandiflorum Lam. (D. scorpioides [L.] Seyffertitz [non Willd.], Aronicum scorpioides Koch) Cat. 200 und428. Bis 2855 m: «Nant rouge» an der Dent de Mordes (Garns); eine andere hohe Stelle ist: Chenalette am Gr. St. Bernhard, 2700 m (Melly).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Design, synthesis and evaluation of novel curcumin analog as potential anti-lung cancer agent
Creators: name: Yang, Jing-Jing
name: Chen, Xiao-Yan
name: Song, Dan-Dan
name: Huang, Li-Li
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Curcumin is a polyphenolic compound derived from the plant turmeric and the structural instability of which limits its further clinical applications. In this study, 11 curcumin analogs with more stable scaffold were prepared and evaluated. The results indicated that the optimal compound Y-11 exhibited the strongest antiproliferative activities against lung cancer cells including H460 and H1650. Further studies showed that Y-11 potentially inhibited hDHODH, induced cell cycle arrest and apoptosis as well as down-regulated crucial signal pathway protein expression in H1650 cells. In the conclusion, the newly designed curcumin analog Y-11 may be suitable for further development in lung cancer treatment.
Designing antibiotic cycling strategies by determining and understanding local adaptive landscapes
Creators: name: Goulart, Christiane P.
name: Mahmudi, Mentar
name: Crona, Kristina A.
name: Jacobs, Stephen D.
name: Kallmann, Marcelo
name: Hall, Barry G.
name: Greene, Devin C.
name: Barlow, Miriam
Publisher: name: arXiv
Year: 2013
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences

description: The evolution of antibiotic resistance among bacteria threatens our continued ability to treat infectious diseases. The need for sustainable strategies to cure bacterial infections has never been greater. So far, all attempts to restore susceptibility after resistance has arisen have been unsuccessful, including restrictions on prescribing [1] and antibiotic cycling [2,3]. Part of the problem may be that those efforts have implemented different classes of unrelated antibiotics, and relied on removal of resistance by random loss of resistance genes from bacterial populations (drift). Here, we show that alternating structurally similar antibiotics can restore susceptibility to antibiotics after resistance has evolved. We found that the resistance phenotypes conferred by variant alleles of the resistance gene encoding the TEM β-lactamase (blaTEM) varied greatly among 15 different β-lactam antibiotics. We captured those differences by characterizing complete adaptive landscapes for the resistance alleles blaTEM-50 and blaTEM-85, each of which differs from its ancestor blaTEM-1 by four mutations. We identified pathways through those landscapes where selection for increased resistance moved in a repeating cycle among a limited set of alleles as antibiotics were alternated. Our results showed that susceptibility to antibiotics can be sustainably renewed by cycling structurally similar antibiotics. We anticipate that these results may provide a conceptual framework for managing antibiotic resistance. This approach may also guide sustainable cycling of the drugs used to treat malaria and HIV.