cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Transgenic laboratory animals in gene regulation research
Creators: name: Krogh-Pedersen, Helene
Publisher: name: Scandinavian Journal of Laboratory Animal Sciences
Year: 2019

description: The knowledge of how genes are regulated in mammals has increased enormously since the development of the first transgenic mice in the early 19805. Up to then, studies of gene regulation were carried out in cultured cell lines. The advantages of investigating gene regulation in transgenic animals as opposed to cell culture systems. are manifold, e.g, allowing the study of expression of the transgene in every cell type and in relation to development. The term gene regulation implies that genes, present in all cells in the body. are directed to expression in specific cell types, at a specific level and at a developmentally correct time. This is brought about by the influence of DNA regions flanking the individual genes. Thus, the tissue specificity of a gene is defined by the surrounding DNA regions. Some of the types of DNA regions which are responsible for the expression pattern of a specific gene, are named promoters and enhancers. The promoter is positioned in front ofthe gene close to the transcription start site. and is responsible for correct transcription initiation. The enhancer strongly enhances the transcription from the promoter, and is able to do so regardless of its position and orientation. Consequently, the enhancer can be positioned in front of. behind or within the gene which it regulates. Both promoters and enhancers are able to bind transcription factors, which are proteins that by binding to DNA. take part in gene regulation. In recent years, studies carried out in transgenic mice have made it possible to identify new types of control regions in addition to promoters and enhancers. Thus. the locus control regions (LCR) from the human B-like globin locus is able to confer tissue specific. position independent expression of human B-globin genes in transgenic mice. It is likely that LCRs from different genes will become important in gene rgulation studies in transgenic mice, as position independent expression of transgenes may be obtained by including an LCR in the microinjected construct. However, so far LCRs have been characterized in only a small number of genes. Individual transgenic mice produced by microinjection carrying identical transgenes, express the transgenes at highly varying levels, depending on the site in the genome at which the transgene has integrated. This is clue to the position~effect, that is, the expression of the integrated transgene is influenced by the surrounding DNA. Hopefully, in the future, a better understanding of the mechanisms causing the position-effect, will lead to the development of vector»systems that allow transgene expression which is independent of the site of integrations.
description: Scandinavian Journal of Laboratory Animal Sciences, Vol. 22 No. 2 (1995)
A Pair Measurement Surface Code on Pentagons
Creators: name: Gidney, Craig
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper, I present a way to compile the surface code into two-body parity measurements ("pair measurements"), where the pair measurements run along the edges of a Cairo pentagonal tiling. The resulting circuit improves on prior work by Chao et al. by using fewer pair measurements per four-body stabilizer measurement (5 instead of 6) and fewer time steps per round of stabilizer measurement (6 instead of 10). Using Monte Carlo sampling, I show that these improvements increase the threshold of the surface code when compiling into pair measurements from $\approx 0.2\%$ to $\approx 0.4\%$, and also that they improve the teraquop footprint at a $0.1\%$ physical gate error rate from $\approx6000$ qubits to $\approx3000$ qubits. However, I also show that the teraquop footprint of Chao et al's construction improves more quickly than mine as physical error rate decreases, and is likely better below a physical gate error rate of $\approx 0.03\%$ (due to bidirectional hook errors in my construction). I also compare to the planar honeycomb code, showing that although this work does noticeably reduce the gap between the surface code and the honeycomb code (when compiling into pair measurements), the honeycomb code is still more efficient (threshold $\approx 0.8\%$, teraquop footprint at $0.1\%$ of $\approx 1000$).
Украинская система высшего образования на пути к университетской автономии
Creators: name: Владимировна, Шевченко Валентина
Publisher: name: Zenodo
Year: 2018
Subjects: Украина
высшее образование
Болонский процесс
автономия университета
реформа образования

description: На русском: [Шевченко В.В. Украинская система высшего образования на пути к университетской автономии // Тезисы 3-й международной научно-практической интернет-конференции "Современное движение науки", 01-02 октября 2018 г. – Днепр: Издательство Международного электронного научно-практического журнала "WayScience", 2018. – С. 704-708. https://doi.org/10.5281/zenodo.2532541]

Обсуждается университетская автономия как обязательный компонент реформы высшего образования Украины по Болонской модели.

Ключевые слова: Украина, высшее образование, Болонский процесс, автономия университета, реформа образования.

Сборник на сайте издательства. Репозиторий НТУ "ХПИ" – скачать pdf

In English: [Shevchenko ValentinaV. (2018) Ukrainian system of higher education on the way to university autonomy (rus.) / Theses of the 3rd international scientific-practical Internet conference "Modern movement of science", October 01-02, 2018, Ukraine, Dnipro, Journal "WayScience", pp. 704-708. https://doi.org/10.5281/zenodo.2532541]
Exploration of Barriers related to family planning use among pastoralist communities of Ethiopian Somali region, Eastern Ethiopia: Qualitative study.
Creators: name: Gemu Tiru
Publisher: name: Zenodo
Year: 2017

description: Background: Rapid population growth is a threat to wellbeing in the poorest countries. In Ethiopia there was a dramatic increase in contraceptive prevalence rate (CPR) from 8.2% to 36% in 2016. Although such encouraging results have been achieved, there are significant variations among the regions, with very low coverage in the pastoralist regions ranging from 1.5 percent in Somali region to 56 percent in Addis Ababa. No studies in Somali region have qualitatively explored for barriers accessing and utilizing family planning from the pastoralist community perspective. Objectives: The objective of this study was exploring barriers related to family planning use among pastoralist communities of Ethiopian Somali region.
Emergent One-Dimensional Helical Channel in Higher-Order Topological Insulators with Step Edges
Creators: name: Sekine, Akihiko
name: Ohtomo, Manabu
name: Kawaguchi, Kenichi
name: Ohfuchi, Mari
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study theoretically the electronic structure of three-dimensional (3D) higher-order topological insulators in the presence of step edges. We numerically find that a 1D conducting state with a helical spin structure, which also has a linear dispersion near the zero energy, emerges at a step edge and on the opposite surface of the step edge. We also find that the 1D helical conducting state on the opposite surface of a step edge emerges when the electron hopping in the direction perpendicular to the step is weak. In other words, the existence of the 1D helical conducting state on the opposite surface of a step edge can be understood by considering an addition of two different-sized independent blocks of 3D higher-order topological insulators. On the other hand, when the electron hopping in the direction perpendicular to the step is strong, the location of the emergent 1D helical conducting state moves from the opposite surface of a step edge to the dip ($270^{\circ}$ edge) just below the step edge. In this case, the existence at the dip below the step edge can be understood by assigning each surface with a sign ($+$ or $-$) of the mass of the surface Dirac fermions. These two physical pictures are connected continuously without the bulk bandgap closing. Our finding paves the way for on-demand creation of 1D helical conducting states from 3D higher-order topological insulators employing experimental processes commonly used in thin-film devices, which could lead to, e.g., a realization of high-density Majorana qubits.
description: 15 pages, 13 figures
Hochschild and cyclic homology of the crossed product of algebraic irrational rotational algebra by finite subgraoups of $SL(2,\mathbb Z)$
Creators: name: Quddus, Safdar
Publisher: name: arXiv
Year: 2014
Subjects: subject: K-Theory and Homology (math.KT)
subject: FOS: Mathematics
subject: 58B34 (Primary), 19D55 (Secondary)

description: Let $Γ\subset SL(2, \mathbb Z)$ be a finite subgroup acting on the irrational rotational algebra $\mathcal A_θ$ via the restriction of the canonical action of $SL(2,\mathbb Z)$. Consider the crossed product algebra $\mathcal A_θ^{alg} \rtimes Γ$ obtained by the restriction of the $Γ$ action on the algberaic irrational rotational algebra. In this paper we prove many results on the homology group of the crossed product algebra $\mathcal A_θ^{alg} \rtimes Γ$. We also analyse the case of the smooth crossed product algebra, $\mathcal A_θ\rtimes Γ$ and calculate some of its homology groups.
Evaluation of technical approaches to pronuclei injection
Creators: name: Nilsson, Erik
name: Lendahl, Urban
Publisher: name: Scandinavian Journal of Laboratory Animal Sciences
Year: 2019

description: The transgenic technology makes it possible to introduce specific genetic alterations into the genome of all cells in an organism. This has opened entirely new possibilities to analyse the regulation and function of individual genes in a living animal. We have established a facility for the production of transgenic mice and have generated 37 different transgenic mouse strains. Here we analyse if the frequency of transgenic offspring correlates with the length of the introduced transgene and/or with the genetic background of the injected eggs. Our data suggest that the transgenic frequency is relatively independent of the length of the construct. The genetic background is more important and we find that specific steps in the process of generating transgenic mice are considerably more efficient in an F2 intercross between C57BL6 and CBA than in inbred C57BL6 mice. Finally we discuss how we have used the transgenic technology to analyse the regulation and function of genes in the developing nervous system.
description: Scandinavian Journal of Laboratory Animal Sciences, Vol. 22 No. 2 (1995)
Solar Flare Composition and Thermodynamics from RESIK X-ray Spectra
Creators: name: Sylwester, B.
name: Sylwester, J.
name: Phillips, K. J. H.
name: Kepa, A.
name: Mrosek, T.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Previous estimates of the solar flare abundances of Si, S, Cl, Ar, and K from the RESIK X-ray crystal spectrometer on board the CORONAS-F spacecraft were made on the assumption of isothermal X-ray emission. We investigate the effect on these estimates by relaxing this assumption and instead determining the differential emission measure (DEM) or thermal structure of the emitting plasma by re-analyzing RESIK data for a GOES class M1.0 flare on 2002 November~14 (SOL2002-11-14T22:26) for which there was good data coverage. The analysis method uses a maximum-likelihood (Withbroe--Sylwester) routine for evaluating the DEM. In a first step, called here AbuOpt, an optimized set of abundances of Si, S, Ar, and K is found that is consistent with the observed spectra. With these abundances, the differential emission measure evolution during the flare is found. The abundance optimization leads to revised abundances of silicon and sulfur in the flare plasma: $A({\rm S}) = 6.94 \pm 0.06$ and $A({\rm Si}) = 7.56 \pm 0.08$ (on a logarithmic scale with $A({\rm H}) = 12$). Previously determined abundances of Ar, K, and Cl from an isothermal assumption are still the preferred values. During the flare's maximum phase, the X-ray-emitting plasma has a basically two-temperature structure, with the cooler plasma with approximately constant temperature (3--6~MK) and a hotter plasma with temperature $16-21$~MK. Using imaging data from the RHESSI hard X-ray spacecraft, the emission volume of the hot plasma is deduced from which lower limits of the electron density $N_e$ and the thermal content of the plasma are given.
description: 7 figures
Украинская система высшего образования на пути к университетской автономии
Creators: name: Владимировна, Шевченко Валентина
Publisher: name: Zenodo
Year: 2018
Subjects: Украина
высшее образование
Болонский процесс
автономия университета
реформа образования

description: Опубликовано: [Шевченко В.В. Украинская система высшего образования на пути к университетской автономии // Тезисы 3-й международной научно-практической интернет-конференции "Современное движение науки", 01-02 октября 2018 г. – Днепр: Издательство Международного электронного научно-практического журнала "WayScience", 2018. – С. 704-708. https://doi.org/10.5281/zenodo.2532541]

Обсуждается университетская автономия как обязательный компонент реформы высшего образования Украины по Болонской модели.

Ключевые слова: Украина, высшее образование, Болонский процесс, автономия университета, реформа образования.

Сборник на сайте издательства. Репозиторий НТУ "ХПИ" – скачать pdf
Superluminal Propagation and Acausality of Nonlinear Massive Gravity
Creators: name: Deser, S.
name: Izumi, K.
name: Ong, Y. C.
name: Waldron, A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Massive gravity is an old idea: trading geometry for mass. Much effort has been expended on establishing a healthy model, culminating in the current ghost-free version. We summarize here our recent findings -- that it is still untenable -- because it is locally acausal: CTC solutions can be constructed in a small neighborhood of any event.
description: Contribution to Conference in Honour of the 90th Birthday of Freeman Dyson -- To Appear in Proceeding. v2: Explicit CTC example, and other improvements, added
Dynamics of Field Induced Polarization Reversal in Strained Perovskite Ferroelectric Films with c-oriented Polarization
Creators: name: Baudry, Laurent
name: Luk'yanchuk, Igor A.
name: Razumnaya, Anna
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The field-induced polarization reversal in $c$-oriented ferroelectric phase of strained perovskite film has been studied. We show that in additional to the conventional longitudinal switching mechanism, when c-oriented polarization vector changes its modulus, the longitudinal-transversal and transversal mechanisms when the perpendicular component of polarization is dynamically admixed are possible. The later process can occurs either via the straight-abrupt or initially-continues polarization turnover scenario. We specified the obtained results for the case of PbTiO$_{3}$ and BaTiO$_{3}$ ferroelectrics and propose the experimental methods for their investigation.
description: 4 pages, 3 figures
Current State of Production, Research and use of Transgenic Laboratory Animals.
Creators: name: Hjorth, Peter
Publisher: name: Scandinavian Journal of Laboratory Animal Sciences
Year: 2019

description: Transgenic techniques have prompted major contributions to a number of research areas of biology and medicine. Transgenic mice are produced by three methods: transfection with viral vectors. DNA injection of egg nuclei, and from genetically altered embryonic stem cells Most widely used in mice and the only available method for other laboratory mammals is that of DNA injection. By this method the genomic insertion of foreign DNA relies on enzymatic processes active at random breaks in chromosome. In addition. ligation and homologous recombination processes take place between injected DNA molecules in the nucleoplasm, resulting in multiple copies per insert. Gene expression from an inserted transgene varies considerably depending on its position in the genome‘ and it is only recently that attempts to overcome this has been successful. Animals showing symptoms known from human diseases can be used as models for the development of new therapies. Many transgenic animal models have been made for both dominantly and rocossively inherited diseases. but still only a few for polygenic or complex immunological and cardiovascular diseases, and for the acquired infection and cancer diseases. These models are used extensively in both basic and applied biomedical research. Future improvements in the transgenesis techniques can result from the use of more suitable retroviral vectors and from the use oflarger DNA constructs for pronuclear injection. These could accommodate multiple genes as well as their genetic co-ordination. Finally, there will be wide applications for the current development of genetic switches for turning transgenes off and on by the use of site specific recombination.
description: Scandinavian Journal of Laboratory Animal Sciences, Vol. 22 No. 2 (1995)
Time-aware Dynamic Graph Embedding for Asynchronous Structural Evolution
Creators: name: Yang, Yu
name: Yin, Hongzhi
name: Cao, Jiannong
name: Chen, Tong
name: Nguyen, Quoc Viet Hung
name: Zhou, Xiaofang
name: Chen, Lei
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: Dynamic graphs refer to graphs whose structure dynamically changes over time. Despite the benefits of learning vertex representations (i.e., embeddings) for dynamic graphs, existing works merely view a dynamic graph as a sequence of changes within the vertex connections, neglecting the crucial asynchronous nature of such dynamics where the evolution of each local structure starts at different times and lasts for various durations. To maintain asynchronous structural evolutions within the graph, we innovatively formulate dynamic graphs as temporal edge sequences associated with joining time of vertices (ToV) and timespan of edges (ToE). Then, a time-aware Transformer is proposed to embed vertices' dynamic connections and ToEs into the learned vertex representations. Meanwhile, we treat each edge sequence as a whole and embed its ToV of the first vertex to further encode the time-sensitive information. Extensive evaluations on several datasets show that our approach outperforms the state-of-the-art in a wide range of graph mining tasks. At the same time, it is very efficient and scalable for embedding large-scale dynamic graphs.
Symmetries of the Maxwell-Bloch equations with the rotating wave approximation
Creators: name: Casu, Ioan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: In this paper a symplectic realization for the Maxwell-Bloch equations with the rotating wave approximation is given, which also leads to a Lagrangian formulation. We show how Lie point symmetries generate a third constant of motion for the considered dynamical system.
Gallium Arsenide (GaAs) Quantum Photonic Waveguide Circuits
Creators: name: Wang, Jianwei
name: Santamato, Alberto
name: Jiang, Pisu
name: Bonneau, Damien
name: Engin, Erman
name: Silverstone, Joshua W.
name: Lermer, Matthias
name: Beetz, Johannes
name: Kamp, Martin
name: Hofling, Sven
name: Tanner, Michael G.
name: Natarajan, Chandra M.
name: Hadfield, Robert H.
name: Dorenbos, Sander N.
name: Zwiller, Val
name: O'Brien, Jeremy L.
name: Thompson, Mark G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Integrated quantum photonics is a promising approach for future practical and large-scale quantum information processing technologies, with the prospect of on-chip generation, manipulation and measurement of complex quantum states of light. The gallium arsenide (GaAs) material system is a promising technology platform, and has already successfully demonstrated key components including waveguide integrated single-photon sources and integrated single-photon detectors. However, quantum circuits capable of manipulating quantum states of light have so far not been investigated in this material system. Here, we report GaAs photonic circuits for the manipulation of single-photon and two-photon states. Two-photon quantum interference with a visibility of 94.9 +/- 1.3% was observed in GaAs directional couplers. Classical and quantum interference fringes with visibilities of 98.6 +/- 1.3% and 84.4 +/- 1.5% respectively were demonstrated in Mach-Zehnder interferometers exploiting the electro-optic Pockels effect. This work paves the way for a fully integrated quantum technology platform based on the GaAs material system.
description: 10 pages, 4 figures
Additional file 2 of New viral biogeochemical roles revealed through metagenomic analysis of Lake Baikal
Creators: name: Coutinho, F. H.
name: P. J. Cabello-Yeves
name: R. Gonzalez-Serrano
name: R. Rosselli
name: M. López-Pérez
name: T. I. Zemskaya
name: A. S. Zakharenko
name: V. G. Ivanov
name: F. Rodriguez-Valera
Publisher: name: figshare
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Ecology

description: Figure S1. Canonical Correspondence Analysis depicting the associations among the abundances of viruses (grouped at the level of phylum, or class in the case of Proteobacteria) and prokaryote taxa (grouped at the level of phyla, or class in the case of Proteobacteria) across samples. Coloured dots represent samples, red taxon names represent prokaryote abundances and arrows represent viral group abundances. (PDF 6.83 kb)
Improved conformalized quantile regression
Creators: name: Sousa, Martim
name: Tomé, Ana Maria
name: Moreira, José
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Conformalized quantile regression is a procedure that inherits the advantages of conformal prediction and quantile regression. That is, we use quantile regression to estimate the true conditional quantile and then apply a conformal step on a calibration set to ensure marginal coverage. In this way, we get adaptive prediction intervals that account for heteroscedasticity. However, the aforementioned conformal step lacks adaptiveness as described in (Romano et al., 2019). To overcome this limitation, instead of applying a single conformal step after estimating conditional quantiles with quantile regression, we propose to cluster the explanatory variables weighted by their permutation importance with an optimized k-means and apply k conformal steps. To show that this improved version outperforms the classic version of conformalized quantile regression and is more adaptive to heteroscedasticity, we extensively compare the prediction intervals of both in open datasets.
description: 11 pages, 10 figures
Ab initio study of topological surface states of strained HgTe
Creators: name: Wu, Shu-Chun
name: Yan, Binghai
name: Felser, Claudia
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The topological surface states of mercury telluride (HgTe) are studied by ab initio calculations assuming different strains and surface terminations. For the Te-terminated surface, a single Dirac cone exists at the $Γ$ point. The Dirac point shifts up from the bulk valence bands into the energy gap when the substrate-induced strain increases. At the experimental strain value (0.3%), the Dirac point lies slightly below the bulk valence band maximum. A left-handed spin texture was observed in the upper Dirac cone, similar to that of the Bi$_2$Se$_3$-type topological insulator. For the Hg-terminated surface, three Dirac cones appear at three time-reversal-invariant momenta, excluding the $Γ$ point, with nontrivial spin textures.
description: 4 pages, 3 figures
Unusual ferrimagnetism in CaFe2O4
Creators: name: Ueda, Hiroki
name: Skoropata, Elizabeth
name: Piamonteze, Cinthia
name: Hernandez, Nazaret Ortiz
name: Burian, Max
name: Tanaka, Yoshikazu
name: Klauser, Christine
name: Damerio, Silvia
name: Noheda, Beatriz
name: Staub, Urs
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Incomplete cancellation of collinear antiparallel spins gives rise to ferrimagnetism. Even if the oppositely polarized spins are owing to the equal number of a single magnetic element having the same valence state, in principle, a ferrimagnetic state can still arise from the crystallographic inequivalence of the host ions. However, experimental identification of such a state as ferrimagnetic is not straightforward because of the tiny magnitude expected for M and the requirement for a sophisticated technique to differentiate similar magnetic sites. We report a synchrotron-based resonant x-ray investigation at the Fe L2,3 edges on an epitaxial film of CaFe2O4, which exhibits two magnetic phases with similar energies. We find that while one phase of CaFe2O4 is antiferromagnetic, the other one is ferrimagnetic with an antiparallel arrangement of an equal number of spins between two distinct crystallographic sites with very similar local coordination environments. Our results further indicate two distinct origins of an overall minute M; one is intrinsic, from distinct Fe3+ sites, and the other one is extrinsic, arising from defective Fe2+ likely forming weakly-coupled ferrimagnetic clusters. These two origins are uncorrelated and have very different coercive fields. Hence, this work provides a direct experimental demonstration of ferrimagnetism solely due to crystallographic inequivalence of the Fe3+ as the origin of the weak M of CaFe2O4.
description: 14 pages, 8 figures
Embryo technology in laboratory animals
Creators: name: Buehr, Mia
Publisher: name: Scandinavian Journal of Laboratory Animal Sciences
Year: 2019

description: Recent progress in genetics has been in part due to progress in embryo technology, as new developments in embryology have made increasingly sophisticated genetic manipulations possible. Although post-implantation embryos may in some cases be used as experimental subjects. most procedures make use of pre-implantation stages. Techniques such as in Vitro culture and fertilisation of embryos, embryo transfer and the cryopreservation of gametes and embryos are now routine in many laboratories. and play an important part in the creation of genetically manipulated animals. The production of chimaeras has also become routine. Aggregation chimaeras have been made for some years‘ while injection chimaeras (created by the injection of embryonic stem cells or blastomeres into the blastocyst cavity) play an important part in the production of mice with alterations o specific genes (the process of "gene targeting").The techniques of embryo cloning and embryo biopsy have also found practical applications in animal production and medicine. But one of the most significant advances in embryo technology has been the development of embryonic stem cells (ES cells), lines of cultured cells that can, when introduced into a host blastocyst, participate in the formation of all tissues. Animals can thus be produced carrying genetic alterations induced in ES cells. Although at present ES cells are available for only a few strains of mice, it is expected that in the future ES cell lines from other species will be developed.
description: Scandinavian Journal of Laboratory Animal Sciences, Vol. 22 No. 2 (1995)
Additional file 1 of Analysis of risk factors and prevention strategies for functional delayed gastric emptying in 1243 patients with distal gastric cancer
Creators: name: Pang, Tao
name: Yin, Xiao-Yi
name: Hang-Tian Cui
name: Lu, Zheng-Mao
name: Nie, Ming-Ming
name: Yin, Kai
name: Guo-En Fang
name: Tian-Hang Luo
name: Xu-Chao Xue
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1 : Supplementary Material Flow diagram of patients enrollment and study design
Braid Representations from Unitary Braided Vector Spaces
Creators: name: Galindo, César
name: Rowell, Eric C.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 20F36, 20C25

description: We investigate braid group representations associated with unitary braided vector spaces, focusing on a conjecture that such representations should have virtually abelian images in general and finite image provided the braiding has finite order. We verify this conjecture for the two infinite families of Gaussian and group-type braided vector spaces, as well as the generalization to quasi-braided vector spaces of group-type.
Studies on a complete experiment for single pseudoscalar meson photoproduction
Creators: name: Wunderlich, Y.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The complete experiment problem for photoproduction of single pseudoscalar mesons is reviewed briefly. If this problem is investigated in the context of a truncated partial wave analysis, the chance emerges to obtain a unique multipole solution measuring less polarization observables than demanded by the classical solution of the problem that is formulated in terms of spin amplitudes.
description: 4 pages, 3 figures, Proceedings of the NSTAR2013 conference, written for the CB-ELSA/TAPS collaboration
Deep Fidelity in DNN Watermarking: A Study of Backdoor Watermarking for Classification Models
Creators: name: Hua, Guang
name: Teoh, Andrew Beng Jin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Backdoor watermarking is a promising paradigm to protect the copyright of deep neural network (DNN) models. In the existing works on this subject, researchers have intensively focused on watermarking robustness, while the concept of fidelity, which is concerned with the preservation of the model's original functionality, has received less attention. In this paper, focusing on deep image classification models, we show that the existing shared notion of the sole measurement of learning accuracy is inadequate to characterize backdoor fidelity. Meanwhile, we show that the analogous concept of embedding distortion in multimedia watermarking, interpreted as the total weight loss (TWL) in DNN backdoor watermarking, is also problematic for fidelity measurement. To address this challenge, we propose the concept of deep fidelity, which states that the backdoor watermarked DNN model should preserve both the feature representation and decision boundary of the unwatermarked host model. To achieve deep fidelity, we propose two loss functions termed penultimate feature loss (PFL) and softmax probability-distribution loss (SPL) to preserve feature representation, while the decision boundary is preserved by the proposed fix last layer (FixLL) treatment, inspired by the recent discovery that deep learning with a fixed classifier causes no loss of learning accuracy. With the above designs, both embedding from scratch and fine-tuning strategies are implemented to evaluate the deep fidelity of backdoor embedding, whose advantages over the existing methods are verified via experiments using ResNet18 for MNIST and CIFAR-10 classifications, and wide residual network (i.e., WRN28_10) for CIFAR-100 task. PyTorch codes are available at https://github.com/ghua-ac/dnn_watermark.
description: Published in Pattern Recognition
Experience from sentinel health monitoring in units containing rats and mice in experiments
Creators: name: Hansen, Axel Kornerup
name: Skovgaard-Jensen, Hams-Jorgen
Publisher: name: Scandinavian Journal of Laboratory Animal Sciences
Year: 2019

description: The paper contains the results of 15 months of sentinel health monitoring in four different animal units, of which three were protected by a barrier, and one was operated without any protective procedures. Rat and mouse sentinels were placed in the units on contaminated bedding for three months and hereafter tested for the following infections: Ectromelia Virus, Kilham Rat Virus (KRV), Lymphocytz's Choriomeningizis Virus (LCM), Minute Virus of Mice (MVMj, Mouse Hepatitis Virus (MHV), Pneumoniuvirus of Mice (PVM), Rai Coronavirus, Reovirus type 3, Sendai Virus, Theiler’s Encephalomyelitis Virus (TMEV), Toolan’s H1 Virus, Bordetella branchisepzica, Citrobacler freundii. Clostridium piliforme, Corynebacterium kutscheri, Mycaplasma spp, Pasteurella pneumotropica, Salmonellae, B-haemolytic Streptoeocci, Streptococcus pneumoniae, arthropods, helminths, Eimeria rpp and flagellates. The outcome of the sentinel investigations were compared with the knowledge on the health status of those animals, which were purchased for experiments in the four units. In the non-proteeted unit antibodies to KR V, PVM and C1 piliforme were refound in the sentinel rats, as it had been found in the purchased animals. Additionally, eggs of Syphacia spp. were found in the non-proteeted unit. P. pneumnrropica, which was also introduced into three of the units with purchased rats and mice, was cultivated from sentinel mice, only, and not from sentinel rats. Both rat and mouse sentinels were found positive to P1 pneumotropica by serology. PVM and C. piliforme, which had been introduced with purchased gerbils and rats and were refound in the sentinel rats, were not found in the sentinel mice. MH V and Rat Coronaviruses were, independently, detected in two of the units. Both coronaviruses were easily eradicated by simply euthanizing all animals of the susceptible species with no precautions taken against animals of other species within the unit. LCM did not spread from experimentally infected mice to the sentinels. Concerning the use of serology for coronaviruses, parvoviruses, C. piliforme and P. pneumotropica it is concluded that the dirty bedding technique proved efficient. For bacteriological and parasitological investigations in general, as well as for serological investigations for LCM and PVM, the method seemed less efficient.
description: Scandinavian Journal of Laboratory Animal Sciences, Vol. 22 No. 1 (1995)
Bremsstrahlung from Neutrino Scattering via Magnetic Dipole Moments
Creators: name: Asteriadis, Konstantin
name: Triviño, Alejandro Quiroga
name: Spinrath, Martin
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In this paper we discuss bremsstrahlung induced by neutrino scattering. This process should exist since neutrinos are expected to couple to photons via magnetic dipole and transition moments. These moments are loop-induced and tiny in the Standard Model with neutrino masses but could be significantly enhanced in extended theories. As concrete example we study the scattering of the two largest neutrino fluxes on earth, solar neutrinos and Cosmic Neutrino Background (CNB). It is tempting to consider this as a potential signature for CNB searches but it turns out that the signal is extremely small and unlikely to be observed.
description: 7 pages, 4 figures; version accepted for publication in IJMPA
Technical note: A simple technique for intubating rats
Creators: name: Bollen, Peter
Publisher: name: Scandinavian Journal of Laboratory Animal Sciences
Year: 2019

description: Rats were anaesthetised with fentanyl-fluanisone and midazolami After 26 i 13 minutes the animals were relaxed enough for endotracheal intubation. A modified Venflon 2® intravenous cannula of 16 G was used for intubating the trachea, which was monitored with an otoscope. The technique described is a successful, atraumatic method of endotracheal intubation of the rat.
description: Scandinavian Journal of Laboratory Animal Sciences, Vol. 21 No. 4 (1994)
About the Future of Laboratory Animal Science in Europe
Creators: name: Weihe, Wolf H
Publisher: name: Scandinavian Journal of Laboratory Animal Sciences
Year: 2019

description: During its short history of 50 years beginning after the Second Great War in the middle of this century it took more than 20 years until the concern about the welfare of laboratory animals had been worked out into a science for laboratory animals. After a short period of confirmation in the later seventies the new science was questioned under the rising opposition to the use of animals as a method for biomedical research by animal protectionists, antiviviseetionists and moralists. During the eighties the unexpected dogmatic opposition caused much confusion and uncertainty that called for a reflection on the significance and scope of LAS. The science began to question its own identity. Some scientists diverted from their former tasks and engaged themselves in animal replacement methods or turned to animal protection. These conflicts within LAS culminated during the late eighties and have not yet ceased. The future of LAS is determined by the controversial views of supporters and of opponents of biomedical research. LAS can fulfil its area of responsibilities satisfactorily only as long as it maintains its involvement and interests in biomedical research. A splitting of responsibilities with diversion to animal protection will be the same as moving into two opposite directions. Sincere support and sympathy with animal protection and antiviviseetion will make LAS obsolete and, in fact, unnecessary. The future depends on the demands of the society for health and welfare ofthe individual, public opinion, and legislation.
description: Scandinavian Journal of Laboratory Animal Sciences, Vol. 21 No. 4 (1994)
Nonvanishing of twists of $L$-functions attached to Hilbert modular forms
Creators: name: Ryan, Nathan C.
name: Tornaria, Gonzalo
name: Voight, John
Publisher: name: arXiv
Year: 2014
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: We describe algorithms for computing central values of twists of $L$-functions associated to Hilbert modular forms, carry out such computations for a number of examples, and compare the results of these computations to some heuristics and predictions from random matrix theory.
description: 19 pages
Additional file 1 of Misperception of sleep in bipolar disorder: an exploratory study using questionnaire versus actigraphy
Creators: name: Ihler, Henrik Myhre
name: Meyrel, Manon
name: Hennion, Vincent
name: Maruani, Julia
name: Gross, Gregory
name: Geoffroy, Pierre A.
name: Lagerberg, Trine Vik
name: Melle, Ingrid
name: Bellivier, Frank
name: Scott, Jan
name: Etain, Bruno
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Additional file 1: Table S1. Correlations between self-rated TST, SL and SE (measured by the PSQI) and sleep misperception variables. Table S2. Comparisons between individuals with BD type 1 and BD type 2 for demographics, clinical and sleep variables. Individuals with BD type not otherwise specified were excluded (n=2). Table S3. Associations between misperception of sleep and demographic and clinical variables in HC (n=63). Table S4. Associations between misperception of sleep and demographic and clinical variables in individuals with BD (n=133). Table S5. Associations between misperception of sleep and demographic and clinical variables in individuals with BD type 1 (n=100). Table 6. Associations between misperception of sleep and demographic and clinical variables in individuals with BD type 2 (n=31).
Boosting New Physics Searches in $t\bar{t}Z$ and $tZj$ Production with Angular Moments
Creators: name: Abraham, Roshan Mammen
name: Gonçalves, Dorival
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The angular moments for the $Z$ boson can be used as analyzers for the underlying production dynamics for the $t\bar t Z$ and $t Zj$ processes. In this manuscript, we derive these angular moments at leading and next-to-leading order in QCD at the LHC. We show that these observables work as efficient probes to beyond the Standard Model effects, considering the Standard Model Effective Field theory framework. Remarkably, we observe that these probes unveil blind directions to CP-odd operators, providing sizable new physics sensitivity at the 14 TeV LHC with 3 ab$^{-1}$ of data.
description: 7 pages, 6 figures, 3 tables, matches published version, updated references
Macroinvertebrados acuáticos como indicadores de calidad del agua en Colombia
Creators: name: Castillo-Figueroa, Dennis
name: Garzón-Salamanca, Laura
name: Albarracín, Juan
Publisher: name: Zenodo
Year: 2019
Subjects: Aquatic insects
Biotic indices
BMWP
Diversity indices
Lentic ecosystems
Lotic ecosystems
Water pollution

description: Colombia es uno de los países con mayor riqueza hídrica del mundo. Sin embargo, diferentes presiones antropogénicas han generado un deterioro en la calidad de sus diversos ecosistemas acuáticos. Los macroinvertebrados han sido útiles en la evaluación de la calidad del agua durante los últimos 50 años. Recopilar la producción bibliográfica es importante para evaluar el progreso de la bioindicación, definir prioridades en el desarrollo de investigaciones futuras, e identificar vacíos de conocimiento sobre este tema en el país. Por esta razón, desarrollamos una revisión sistemática, seleccionando 109 referencias para analizar la producción científica relacionada con la evaluación de la calidad del agua en los ecosistemas acuáticos colombianos, con base en el uso de los macroinvertebrados acuáticos. Describimos características bibliográficas, geográficas, ecológicas y metodológicas de los estudios. El 77,5% de las publicaciones se desarrollaron en las últimas dos décadas. El 83% de los estudios fueron realizados en la región Andina. Los ecosistemas lóticos fueron ampliamente investigados (90%) a diferencia de los lenticos (10%). El principal uso del suelo de los estudios fue agropecuario (38%), seguido del uso doméstico (29,3%), industrial (12,9%), minero (7,1%), hidroeléctirco (6,4%), y de extracción maderera (6,4%). El índice BMWP y los índices de diversidad fueron los más utilizados para los análisis con el 39,3% y el 32,7%, respectivamente. Es necesaria más investigación en ecosistemas lénticos, puesto que están siendo severamente impactados pero muy pocos han sido evaluados. Más estudios se requieren en regiones que albergan una alta diversidad de ecosistemas acuáticos (e.g. Amazonia, Orinoquia). Es importante revisar los índices tradicionales de diversidad, en los cuales se deben evitar el uso de premisas equivocadas que relacionan los macroinvertebrados acuáticos y la calidad del agua. Se recomienda tener en cuenta el fundamento de los índices, una mayor resolución taxonómica, y aproximaciones al número efectivo de especies o géneros.
description: Es el mismo resumen presentado en el congreso AQUATROP
Lyapunov exponents in resonance multiplets
Creators: name: Shevchenko, I. I.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: The problem of estimating the maximum Lyapunov exponents of the motion in a multiplet of interacting nonlinear resonances is considered for the case when the resonances have comparable strength. The corresponding theoretical approaches are considered for the multiplets of two, three, and infinitely many resonances (i.e., doublets, triplets, and "infinitets"). The analysis is based on the theory of separatrix and standard maps. A "multiplet separatrix map" is introduced, valid for description of the motion in the resonance multiplet under certain conditions. In numerical experiments it is shown that, at any given value of the adiabaticity parameter (which controls the degree of interaction/overlap of resonances in the multiplet), the value of the maximum Lyapunov exponent in the multiplet of equally-spaced equally-sized resonances is minimal in the doublet case and maximal in the infinitet case. This is consistent with the developed theory.
description: 28 pages, 8 figures
Automatic Estimation of Live Coffee Leaf Infection based on Image Processing Techniques
Creators: name: Hitimana, Eric
name: Gwun, Oubong
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Image segmentation is the most challenging issue in computer vision applications. And most difficulties for crops management in agriculture are the lack of appropriate methods for detecting the leaf damage for pests treatment. In this paper we proposed an automatic method for leaf damage detection and severity estimation of coffee leaf by avoiding defoliation. After enhancing the contrast of the original image using LUT based gamma correction, the image is processed to remove the background, and the output leaf is clustered using Fuzzy c-means segmentation in V channel of YUV color space to maximize all leaf damage detection, and finally, the severity of leaf is estimated in terms of ratio for leaf pixel distribution between the normal and the detected leaf damage. The results in each proposed method was compared to the current researches and the accuracy is obvious either in the background removal or damage detection.
description: SIPP 2014 : Second International Conference on Signal, Image Processing and Pattern Recognition,Sydney, Australia
The solution of the Loewy-Radwan conjecture
Creators: name: Omladič, Matjaž
name: Šivic, Klemen
Publisher: name: arXiv
Year: 2022
Subjects: subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics
subject: Primary: 15A18, 15A30, Primary: 15A18, 15A30, Secondary: 20G05

description: A seminal result of Gerstenhaber gives the maximal dimension of a linear space of nilpotent matrices. It also exhibits the structure of this space where the maximal dimension is attained. Extensions of this result in the direction of linear spaces of matrices with a bounded number of eigenvalues have been studied. In this paper, we answer perhaps the most general problem of the kind as proposed by Loewy and Radwan by solving their conjecture in the positive. We give the dimension of a maximal linear space of $n\times n$ matrices with no more than $k
description: Accepted in Linear and Mulilinear algebra, 26 pages