cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Zur Erinnerung an Oscar Heck
Creators: name: Schieck, Siegwalt
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 4, Nr. 3 (1975), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Validation of strategies for coupling exoplanet PSFs into single-mode fibres for high-dispersion coronagraphy
Creators: name: Morsy, M. El
name: Vigan, A.
name: Lopez, M.
name: Otten, G. P. P. L.
name: Choquet, E.
name: Madec, F.
name: Costille, A.
name: Sauvage, J. -F.
name: Dohlen, K.
name: Muslimov, E.
name: Pourcelot, R.
name: Floriot, J.
name: Benedetti, J. -A.
name: Blanchard, P.
name: Balard, P.
name: Murray, G.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: On large ground-based telescopes, the combination of extreme adaptive optics (ExAO) and coronagraphy with high-dispersion spectroscopy (HDS), sometimes referred to as high-dispersion coronagraphy (HDC), is starting to emerge as a powerful technique for the direct characterisation of giant exoplanets. The high spectral resolution not only brings a major gain in terms of accessible spectral features but also enables a better separation of the stellar and planetary signals. Ongoing projects such as Keck/KPIC, Subaru/REACH, and VLT/HiRISE base their observing strategy on the use of a few science fibres, one of which is dedicated to sampling the planet's signal, while the others sample the residual starlight in the speckle field. The main challenge in this approach is to blindly centre the planet's point spread function (PSF) accurately on the science fibre, with an accuracy of less than 0.1 $λ/D$ to maximise the coupling efficiency. In the context of the HiRISE project, three possible centring strategies are foreseen, either based on retro-injecting calibration fibres to localise the position of the science fibre or based on a dedicated centring fibre. We implemented these three approaches, and we compared their centring accuracy using an upgraded setup of the MITHiC high-contrast imaging testbed, which is similar to the setup that will be adopted in HiRISE. Our results demonstrate that reaching a specification accuracy of 0.1 $λ/D$ is extremely challenging regardless of the chosen centring strategy. It requires a high level of accuracy at every step of the centring procedure, which can be reached with very stable instruments. We studied the contributors to the centring error in the case of MITHiC and we propose a quantification for some of the most impacting terms.
Bayesian Nonparametric Weighted Sampling Inference
Creators: name: Si, Yajuan
name: Pillai, Natesh S.
name: Gelman, Andrew
Publisher: name: arXiv
Year: 2013
Subjects: subject: Methodology (stat.ME)
subject: Applications (stat.AP)
subject: Computation (stat.CO)
subject: FOS: Computer and information sciences

description: It has historically been a challenge to perform Bayesian inference in a design-based survey context. The present paper develops a Bayesian model for sampling inference in the presence of inverse-probability weights. We use a hierarchical approach in which we model the distribution of the weights of the nonsampled units in the population and simultaneously include them as predictors in a nonparametric Gaussian process regression. We use simulation studies to evaluate the performance of our procedure and compare it to the classical design-based estimator. We apply our method to the Fragile Family and Child Wellbeing Study. Our studies find the Bayesian nonparametric finite population estimator to be more robust than the classical design-based estimator without loss in efficiency, which works because we induce regularization for small cells and thus this is a way of automatically smoothing the highly variable weights.
description: Published at http://dx.doi.org/10.1214/14-BA924 in the Bayesian Analysis (http://projecteuclid.org/euclid.ba) by the International Society of Bayesian Analysis (http://bayesian.org/)
A multi-dimensional model for the treatment of overweight and obese males in a community setting
Creators: name: Mendoza, Gary
Publisher: name: Cardiff Metropolitan University
Year: 2022
Subjects: Public health not elsewhere classified

description: Background: In the United Kingdom (UK) 65.4% of men are overweight or obese. In England the direct costs of treating obesity were estimated in 2002 at approximately £46 million. Obesity develops when energy intake exceeds energy expenditure over a prolonged time. Reviewing weight loss initiatives reveals that most studies are undertaken on female subjects which may not take account of issues relevant to men. This research takes a multidisciplinary approach to male obesity encompassing nutrition, exercise/activity, and the psychological aspects of behaviour change as proposed in the transtheoretical model of change (TTM) Aims: To determine whether obese and overweight males go through set stages of behavioural change when trying to lose weight. Methods: Study 1 established the effectiveness of psychometric tests as screening tools for weight management. Data on current nutritional and activity habits were collected. Forty six males were recruited. In Study 2 nineteen Trainers delivered a l2-week weight management course, evaluated by weight loss and reduction in waist measurement in 54 Clients. Results: Data from the psychometric tests used in study 1 informed the screening criteria for Study 2. Clients achieved a mean weight loss of 4.65kg (P<0.001) and mean waist circumference reduction of nearly 5cm (P<0.001). In addition, daily steps increased by 3947 (P<0.001) and energy intake decreased by 315 kcal (P<0.05). Weight loss efficacy significantly increased (P<0.01) as did decisional balance difference (P<0.01). An increase in the level of efficacy correlated with reductions in waist measurement (P<0.05). Conclusion: It is possible to train novice trainers to deliver an effective weight management course. Increases in self-efficacy and decisional balance were in line with TTM theory. This research provides a programme of weight management for men, meeting the need for "Accredited Health Trainers" highlighted in the UK government white paper "Choosing Health".
title: Zwei römische Straßenstationen im südlichen Oberrheintal
Creators: name: Fingerlin, Gerhard
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 5, Nr. 1 (1976), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
title: Denkmalpflegerische Gesichtspunkte bei der Sanierung von Einzelobjekten
Creators: name: Hannmann, Eckart
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 5, Nr. 1 (1976), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Higgs Boson Cross Section from CTEQ-TEA Global Analysis
Creators: name: Dulat, Sayipjamal
name: Hou, Tie-Jiun
name: Gao, Jun
name: Huston, Joey
name: Nadolsky, Pavel
name: Pumplin, Jon
name: Schmidt, Carl
name: Stump, Daniel
name: Yuan, C. -P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We study the uncertainties of the Higgs boson production cross section through the gluon fusion subprocess at the LHC (with $\sqrt s=7, 8$ and $14$ TeV) arising from the uncertainties of the parton distribution functions (PDFs) and of the value of the strong coupling constant $α_s(M_Z)$. These uncertainties are computed by two complementary approaches, based on the Hessian and the Lagrange Multiplier methods within the CTEQ-TEA global analysis framework. We find that their predictions for the Higgs boson cross section are in good agreement. Furthermore, the result of the Lagrange Multiplier method supports the prescriptions we have previously provided for using the Hessian method to calculate the combined PDF and $α_s$ uncertainties, and to estimate the uncertainties at the $68\%$ confidence level by scaling them from the $90\%$ confidence level.
description: 34 pages, 9 figures, and 9 tables
Structural Forecasting for Short-term Tropical Cyclone Intensity Guidance
Creators: name: McNeely, Trey
name: Khokhlov, Pavel
name: Dalmasso, Niccolo
name: Wood, Kimberly M.
name: Lee, Ann B.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: Because geostationary satellite (Geo) imagery provides a high temporal resolution window into tropical cyclone (TC) behavior, we investigate the viability of its application to short-term probabilistic forecasts of TC convective structure to subsequently predict TC intensity. Here, we present a prototype model which is trained solely on two inputs: Geo infrared imagery leading up to the synoptic time of interest and intensity estimates up to 6 hours prior to that time. To estimate future TC structure, we compute cloud-top temperature radial profiles from infrared imagery and then simulate the evolution of an ensemble of those profiles over the subsequent 12 hours by applying a Deep Autoregressive Generative Model (PixelSNAIL). To forecast TC intensities at hours 6 and 12, we input operational intensity estimates up to the current time (0 h) and simulated future radial profiles up to +12 h into a ``nowcasting'' convolutional neural network. We limit our inputs to demonstrate the viability of our approach and to enable quantification of value added by the observed and simulated future radial profiles beyond operational intensity estimates alone. Our prototype model achieves a marginally higher error than the National Hurricane Center's official forecasts despite excluding environmental factors, such as vertical wind shear and sea surface temperature. We also demonstrate that it is possible to reasonably predict short-term evolution of TC convective structure via radial profiles from Geo infrared imagery, resulting in interpretable structural forecasts that may be valuable for TC operational guidance.
title: Mitteilungen
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 5, Nr. 1 (1976), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Understanding and predicting food handlers' implementation of specific food safety practices using social cognition models
Creators: name: Clayton, Debbie
Publisher: name: Cardiff Metropolitan University
Year: 2022
Subjects: Food safety, traceability, certification and authenticity

description: This thesis reports on the development and application of research tools to understand and predict caterers' implementation of specific food safety practices. Food handlers' salient beliefs (n=137) identified three specific food safety actions for further investigation: hand hygiene actions, cleaning actions and the appropriate use of utensils when preparing raw and ready to eat foods. A notational analysis coding system was designed and developed. This tool was successful in recording a greater number of cross-contamination events than would have been highlighted using traditional approaches. One hundred and fifteen food handlers from 29 catering businesses were observed carrying out 31,050 food preparation actions in their workplace. Caterers subsequently completed a knowledge questionnaire and the Food Safety Instrument. The Food Safety Instrument was constructed using constructs from the Theory of Planned Behaviour (TPB) and the Health Belief Model. Despite a high level of knowledge and positive attitudes towards food safety, food safety malpractices were common. Implementation of hand hygiene and cleaning practices were particularly poor and only two percent of caterers carried out adequate food safety actions at all times. The TPB provided a useful framework for understanding the factors influencing caterers' implementation of specific food safety practices. Five constructs were identified as predictors of food safety malpractices: attitudes, subjective norms, descriptive norms, perceived behavioural control and intentions. Thus, suggesting that food safety behaviour cannot be improved merely through the provision of information. Food safety initiatives need to encompass a wide variety of factors including the attitudes of caterers, provision of resources and organisational culture. This thesis is important in furthering our knowledge of the factors that determine specific food safety practices and has practical value, providing a framework for both theoretical developments and practical interventions.
Is there a fractional breakdown of the Stokes-Einstein relation in Kinetically Constrained Models at low temperature?
Creators: name: Blondel, Oriane
name: Toninelli, Cristina
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We study the motion of a tracer particle injected in facilitated models which are used to model supercooled liquids in the vicinity of the glass transition. We consider the East model, FA1f model and a more general class of non-cooperative models. For East previous works had identified a fractional violation of the Stokes-Einstein relation with a decoupling between diffusion and viscosity of the form $D\simτ^{-ξ}$ with $ξ\sim 0.73$. We present rigorous results proving that instead $\log(D)=-\log(τ)+O(\log(1/q))$, which implies at leading order $\log(D)/\log(τ)\sim -1$ for very large time-scales. Our results do not exclude the possibility of SE breakdown, albeit non fractional. Indeed extended numerical simulations by other authors show the occurrence of this violation and our result suggests $Dτ\sim 1/q^α$, where $q$ is the density of excitations. For FA1f we prove fractional Stokes Einstein in dimension $1$, and $D\simτ^{-1}$ in dimension $2$ and higher, confirming previous works. Our results extend to a larger class of non-cooperative models.
description: 6 pages, 2 figures; v2: revised version, to appear in EPL
Evolution of Massive Black Hole Binaries in Collisionally Relaxed Nuclear Star Clusters -- Impact of Mass Segregation
Creators: name: Mukherjee, Diptajyoti
name: Zhu, Qirong
name: Ogiya, Go
name: Rodriguez, Carl L.
name: Trac, Hy
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Massive Black Hole (MBH) binaries are considered to be one of the most important sources of Gravitational Waves (GW) that can be detected by GW detectors like LISA. However, there are a lot of uncertainties in the dynamics of MBH binaries in the stages leading up to the GW-emission phase. It has been recently suggested that Nuclear Star Clusters (NSCs) could provide a viable route to overcome the final parsec problem for MBH binaries at the center of galaxies. NSCs are collisional systems where the dynamics would be altered by the presence of a mass spectrum. In this study, we use a suite of high-resolution $N$-body simulations with over 1 million particles to understand how collisional relaxation under the presence of a mass spectrum of NSC particles affects the dynamics of the MBH binary under the merger of two NSCs. We consider MBH binaries with different mass ratios and additional non-relaxed models. We find that mass-segregation driven by collisional relaxation can lead to accelerated hardening in lower mass ratio binaries but has the opposite effect in higher mass ratio binaries. Crucially, the relaxed models also demonstrate much lower eccentricities at binary formation and negligible growth during hardening stages leading to longer merger timescales. The results are robust and highlight the importance of collisional relaxation on changing the dynamics of the binary. Our models are state-of-the-art, use zero softening, and high enough particle numbers to model NSCs realistically.
description: 18 pages, 14 figures. New version with higher resolution simulations. Accepted in MNRAS
Paola Zuccolotto and Marica Manisera (2020): Basketball Data Science: With Applications in R, CRC Press, 243 pp., £80.50 (Hardcover), ISBN: 978-1-138-60079-9
Creators: name: Groll, Andreas
name: Jentsch, Carsten
Publisher: name: TU Dortmund
Year: 2022
Subjects: subject: 310

description: Statistical papers;63(3)
title: Die Dienststellen des Landesdenkmalamtes
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 5, Nr. 1 (1976), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
What does it take to solve the 3D Ising model? Minimal necessary conditions for a valid solution
Creators: name: Viswanathan, G. M.
name: Portillo, M. A. G.
name: Raposo, E. P.
name: da Luz, M. G. E.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Exact solution of the Ising model on the simple cubic lattice is one of the long-standing open problems in rigorous statistical mechanics. Indeed, it is generally believed that settling it would constitute a methodological breakthrough, fomenting great prospects for further application, similarly to what happened when Lars Onsager solved the two dimensional model eighty years ago. Hence, there have been many attempts to find analytic expressions for the exact partition function $Z$, but all such attempts have failed due to unavoidable conceptual or mathematical obstructions. Given the importance of this simple yet paradigmatic model, here we set out clear-cut criteria for any claimed exact expression for $Z$ to be minimally plausible. Specifically, we present six necessary -- but not sufficient -- conditions that $Z$ must satisfy. These criteria will allow very quick plausibility checks of future claims. As illustrative examples, we discuss previous mistaken ``solutions,'' unveiling their shortcomings.
description: 8 pages, minor corrections
The two-dimensional Euler equations in Yudovich type space and $\mathrm{\textbf{bmo}}$-type space
Creators: name: Chen, Qionglei
name: Miao, Changxing
name: Zheng, Xiaoxin
Publisher: name: arXiv
Year: 2013
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We construct global-in-time, unique solutions of the two-dimensional Euler equations in a Yudovich type space and a $\rm bmo$-type space. First, we show the regularity of solutions for the two-dimensional Euler equations in the Spanne space involving an unbounded and non-decaying vorticity. Next, we establish an estimate with a logarithmic loss of regularity for the transport equation in a bmo-type space by developing classical analysis tool such as the John-Nirenberg inequality. We also optimize estimates of solutions to the vorticity-stream formulation of the two-dimensional Euler equations with a bi-Lipschitz vector field in bmo-type space by combining an observation introduced by Yodovich with the so-called "quasi-conformal property" of the incompressible.
description: 39pages. Thanks Philippe Serfati for providing us with his paper: Pertes de r\'egularit\'e le laplacien et l'\'equation d'Euler sui $\mathbb R^n$, priprint.15,pp., 1994."
Superbunching in cathodoluminescence: a master equation approach
Creators: name: Yuge, Tatsuro
name: Yamamoto, Naoki
name: Sannomiya, Takumi
name: Akiba, Keiichirou
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We propose a theoretical model of a master equation for cathodoluminescence (CL). The master equation describes simultaneous excitation of multiple emitters by an incoming electron and radiative decay of individual emitters. We investigate the normalized second-order correlation function, $g^{(2)}(τ)$, of this model. We derive the exact formula for the zero-time delay correlation, $g^{(2)}(0)$, and show that the model successfully describes giant bunching (superbunching) in the CL. We also derive an approximate form of $g^{(2)}(τ)$, which is valid for small excitation rate. Furthermore, we discuss the state of the radiation field of the CL. We reveal that the superbunching results from a mixture of an excited photon state and the vacuum state and that this type of state is realized in the CL.
description: 11+12 pages, 3+6 figures
$pp$ and $\bar pp$ total cross sections and elastic scattering
Creators: name: Donnachie, A.
name: Landshoff, P. V.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: It is shown that $p p$ and $p\bar p$ data, including those from the TOTEM experiment, agree well with Regge theory.
description: 9 pages, 7 figures, Equation (2b) corrected
The SLUGGS Survey: Wide-field Stellar Kinematics of Early-type Galaxies
Creators: name: Arnold, Jacob A.
name: Romanowsky, Aaron J.
name: Brodie, Jean P.
name: Forbes, Duncan A.
name: Strader, Jay
name: Spitler, Lee R.
name: Foster, Caroline
name: Blom, Christina
name: Kartha, Sreeja S.
name: Pastorello, Nicola
name: Pota, Vincenzo
name: Usher, Christopher
name: Woodley, Kristin A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present stellar kinematics of 22 nearby early-type galaxies (ETGs), based on two-dimensional (2D) absorption line stellar spectroscopy out to ~2-4 R_e (effective radii), as part of the ongoing SLUGGS Survey. The galaxies span a factor of 20 in intrinsic luminosity, as well as a full range of environment and ETG morphology. Our data consist of good velocity resolution (sigma_inst ~ 25 km/s) integrated stellar-light spectra extracted from the individual slitlets of custom made Keck/DEIMOS slitmasks. We extract stellar kinematics measurements (V, sigma, h_3, and h_4) for each galaxy. Combining with literature values from smaller radii, we present 2D spatially resolved maps of the large-scale kinematic structure in each galaxy. We find that the kinematic homogeneity found inside 1 R_e often breaks down at larger radii, where a variety of kinematic behaviors are observed. While central slow rotators remain slowly rotating in their halos, central fast rotators show more diversity, ranging from rapidly increasing to rapidly declining specific angular momentum profiles in the outer regions. There are indications that the outer trends depend on morphological type, raising questions about the proposed unification of the elliptical and lenticular (S0) galaxy families in the ATLAS^3D survey. Several galaxies in our sample show multiple lines of evidence for distinct disk components embedded in more slowly rotating spheroids, and we suggest a joint photometric-kinematic approach for robust bulge-disk decomposition. Our observational results appear generally consistent with a picture of two-phase (in-situ plus accretion) galaxy formation.
description: ApJ, published (minor changes from v1); 30 pages, 15 figures; high resolution version available at http://sages.ucolick.org/publications.html
title: Die Dienststellen des Landesdenkmalamtes ; Kulturdenkmale in Baden-Württemberg
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 5, Nr. 2 (1976), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
title: Die Restaurierung der Evangelischen Stadtkirche in Tuttlingen
Creators: name: Becker, Karl
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 6, Nr. 1 (1977), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Real-Time Video Deblurring via Lightweight Motion Compensation
Creators: name: Son, Hyeongseok
name: Lee, Junyong
name: Cho, Sunghyun
name: Lee, Seungyong
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: While motion compensation greatly improves video deblurring quality, separately performing motion compensation and video deblurring demands huge computational overhead. This paper proposes a real-time video deblurring framework consisting of a lightweight multi-task unit that supports both video deblurring and motion compensation in an efficient way. The multi-task unit is specifically designed to handle large portions of the two tasks using a single shared network, and consists of a multi-task detail network and simple networks for deblurring and motion compensation. The multi-task unit minimizes the cost of incorporating motion compensation into video deblurring and enables real-time deblurring. Moreover, by stacking multiple multi-task units, our framework provides flexible control between the cost and deblurring quality. We experimentally validate the state-of-the-art deblurring quality of our approach, which runs at a much faster speed compared to previous methods, and show practical real-time performance (30.99dB@30fps measured in the DVD dataset).
description: Computer Graphics Forum (special issue on Pacific Graphics 2022), 2022; Equal contribution from the first two authors
A randomized, double-blind, 3-arm, parallel study assessing the pharmacokinetics, safety, tolerability and immunogenicity of AVT04, an ustekinumab candidate biosimilar, in healthy adults
Creators: name: Wynne, Christopher
name: Hamilton, Paul
name: McLendon, Kristi
name: Stroissnig, Heimo
name: Smith, Matthew
name: Duijzings, Paul
name: Ruffieux, Ruth
name: Otto, Hendrik
name: Sattar, Abid
name: Haliduola, Halimu N.
name: Leutz, Steffen
name: Berti, Fausto
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: This study assessed pharmacokinetic (PK) similarity, safety, and immunogenicity of AVT04, a candidate biosimilar, compared with reference product (RP) ustekinumab (EU-approved and US-licensed Stelara®). Healthy subjects (N = 298) were randomized 1:1:1 to receive one 45 mg dose of AVT04, EU-RP, or US-RP. The primary PK parameters were Cmax and AUC0-inf. PK similarity was demonstrated if the 90% confidence intervals (CI) for the ratio of geometric means were all contained within the prespecified margins of 80% and 125%. Additional PK parameters, including AUC0-t, were also assessed. Safety and immunogenicity were also assessed until Day 92. After pre-specified protein content normalization, the 90% CI for the ratio of geometric means for primary PK parameters were all contained within the pre-specified bioequivalence margins of 80% and 125%, supporting demonstration of PK similarity between AVT04 and both EU- and US-RP. Secondary PK parameters supported the analysis. Safety and immunogenicity profiles were comparable across all three treatment arms, although the study was not powered to detect small differences in these parameters. Results supported a demonstration of PK similarity between candidate biosimilar AVT04, US-RP and EU-RP. Similar safety and immunogenicity were also shown. Clinical trial registration:www.clinicaltrials.gov identifier is NCT04744363.
Fast Bayesian Inference with Batch Bayesian Quadrature via Kernel Recombination
Creators: name: Adachi, Masaki
name: Hayakawa, Satoshi
name: Jørgensen, Martin
name: Oberhauser, Harald
name: Osborne, Michael A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Numerical Analysis (math.NA)
subject: Computation (stat.CO)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: 62C10, 62F15

description: Calculation of Bayesian posteriors and model evidences typically requires numerical integration. Bayesian quadrature (BQ), a surrogate-model-based approach to numerical integration, is capable of superb sample efficiency, but its lack of parallelisation has hindered its practical applications. In this work, we propose a parallelised (batch) BQ method, employing techniques from kernel quadrature, that possesses an empirically exponential convergence rate. Additionally, just as with Nested Sampling, our method permits simultaneous inference of both posteriors and model evidence. Samples from our BQ surrogate model are re-selected to give a sparse set of samples, via a kernel recombination algorithm, requiring negligible additional time to increase the batch size. Empirically, we find that our approach significantly outperforms the sampling efficiency of both state-of-the-art BQ techniques and Nested Sampling in various real-world datasets, including lithium-ion battery analytics.
description: 38 pages, 6 figures
Amplification limit of weak measurements: a variational approach
Creators: name: Pang, Shengshi
name: Brun, Todd A.
name: Wu, Shengjun
name: Chen, Zeng-Bing
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Post-selected weak measurement has been widely used in experiments to observe weak effects in various physical systems. However, it is still unclear how large the amplification ability of a weak measurement can be and what determines the limit of this ability, which is fundamental to understanding and applying weak measurements. The limitation of the conventional weak value formalism for this problem is the divergence of weak values when the pre- and post-selections are nearly orthogonal. In this paper, we study this problem by a variational approach for a general Hamiltonian $H_{\mathrm{int}}=gA\otimesΩδ(t-t_{0}),\, g\ll1$. We derive a general asymptotic solution, and show that the amplification limit is essentially independent of $g$, and determined only by the initial state of the detector and the number of distinct eigenvalues of $A$ or $Ω$. An example of spin-$\frac{1}{2}$ particles with a pair of Stern-Gerlach devices is given to illustrate the results. The limiting case of continuous variable systems is also investigated to demonstrate the influence of system dimension on the amplification limit.
description: 8 pages, 1 figure. v2 is a major revision of v1. The results are extended to more general interactions, and the degeneracy of the Hamiltonian is considered. Examples for qubit system and continuous-variable system are added
title: Veröffentlichungen des Landesdenkmalamtes
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 6, Nr. 3 (1977), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
title: Die Bedeutung früher elektrischer Maschinen in Württemberg als Kulturdenkmale
Creators: name: Leiner, Wolfgang
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 11, Nr. 1 (1982), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Tunable Quantum Phase Transitions in a Resonant Level Coupled to Two Dissipative Baths
Creators: name: Liu, Dong E.
name: Zheng, Huaixiu
name: Finkelstein, Gleb
name: Baranger, Harold U.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study tunneling through a resonant level connected to two dissipative bosonic baths: one is the resistive environment of the source and drain leads, while the second comes from coupling to potential fluctuations on a resistive gate. We show that several quantum phase transitions (QPT) occur in such a model, transitions which emulate those found in interacting systems such as Luttinger liquids or Kondo systems. We first use bosonization to map this dissipative resonant level model to a resonant level in a Luttinger liquid, one with, curiously, two interaction parameters. Drawing on methods for analyzing Luttinger liquids at both weak and strong coupling, we obtain the phase diagram. For strong dissipation, a Berezinsky-Kosterlitz-Thouless QPT separates strong-coupling and weak-coupling (charge localized) phases. In the source-drain symmetric case, all relevant backscattering processes disappear at strong coupling, leading to perfect transmission at zero temperature. In fact, a QPT occurs as a function of the coupling asymmetry or energy of the resonant level: the two phases are (i) the system is cut into two disconnected pieces (zero transmission), or (ii) the system is a single connected piece with perfect transmission, except for a disconnected fractional degree of freedom. The latter arises from the competition between the two fermionic leads (source and drain), as in the two-channel Kondo effect.
description: 11 pages. Published version: clarifications and added references
Efficacy, safety, and tolerability of ulotaront (SEP-363856, a trace amine-associated receptor 1 agonist) for the treatment of schizophrenia and other mental disorders: a systematic review of preclinical and clinical trials
Creators: name: Le, Gia Han
name: Gillissie, Emily S.
name: Rhee, Taeho Greg
name: Cao, Bing
name: Alnefeesi, Yazen
name: Guo, Ziji
name: Di Vincenzo, Joshua D.
name: Jawad, Muhammad Youshay
name: March, Andrew M.
name: Ramachandra, Ranuk
name: Lui, Leanna M.W.
name: McIntyre, Roger S.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Schizophrenia is a mental illness that can disrupt emotions, perceptions, and cognition and reduce quality of life. The classical approach to treat schizophrenia is to use typical and atypical antipsychotics; however, limitations include low efficacy in mitigating negative symptoms and cognitive dysfunctions and a range of adverse effects. Evidence has accumulated on trace amine-associated receptor 1 (TAAR1) as a novel therapeutic target for treating schizophrenia. This systematic review investigates the available evidence on a TAAR1 agonist, ulotaront, as a treatment for schizophrenia. A systematic search was conducted on PubMed/MEDLINE and Ovid databases for English-published articles from inception to 18 December 2022. The literature focusing on the association between ulotaront and schizophrenia was evaluated based on an inclusion/exclusion criterion. Selected studies were assessed for the risk of bias, using the Cochrane Collaboration tool, and summarized in a table to generate discussion topics. Three clinical, two comparative, and five preclinical studies examining ulotaront’s pharmacology, tolerability and safety, and/or efficacy were identified. Results indicate that ulotaront has a differing adverse effect profile from other antipsychotics, may mitigate metabolic-related adverse effects commonly associated with antipsychotics, and may be effective for treating positive and negative symptoms. Findings from the available literature present ulotaront as a potential and promising alternative treatment method for schizophrenia. Despite this, our results were limited due to the lack of clinical trials on ulotaront’s long-term efficacy and mechanisms of action. Future research should focus on these limitations to elucidate ulotaront’s efficacy and safety for the treatment of schizophrenia and other mental disorders with similar pathophysiology.
Estimating Total Treatment Effect in Randomized Experiments with Unknown Network Structure
Creators: name: Yu, Christina Lee
name: Airoldi, Edoardo M
name: Borgs, Christian
name: Chayes, Jennifer T
Publisher: name: arXiv
Year: 2022
Subjects: subject: Methodology (stat.ME)
subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: Randomized experiments are widely used to estimate the causal effects of a proposed treatment in many areas of science, from medicine and healthcare to the physical and biological sciences, from the social sciences to engineering, to public policy and to the technology industry at large. Here, we consider situations where classical methods for estimating the total treatment effect on a target population are considerably biased due to confounding network effects, i.e., the fact that the treatment of an individual may impact their neighbors' outcomes, an issue referred to as network interference or as non-individualized treatment response. A key challenge in these situations, is that the network is often unknown, and difficult, or costly, to measure. In this paper, we characterize the limitations in estimating the total treatment effect without knowledge of the network that drives interference, assuming a potential outcomes model with heterogeneous additive network effects. This model encompasses a broad class of network interference sources, including spillover, peer effects, and contagion. Within this framework, we show that, surprisingly, given access to average historical baseline measurements prior to the experiment, we can develop a simple estimator and efficient randomized design that outputs an unbiased estimate with low variance. Our solution does not require knowledge of the underlying network structure, and it comes with statistical guarantees for a broad class of models. We believe our results are poised to impact current randomized experimentation strategies due to its ease of interpretation and implementation, alongside its provable theoretical insights under heterogeneous network effects.
Superconducting analogue of the parafermion fractional quantum Hall states
Creators: name: Vaezi, Abolhassan
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Read and Rezayi $Z_k$ parafermion wavefunctions describe $ν=2+\frac{k}{kM+2}$ fractional quantum Hall (FQH) states. These states support non-Abelian excitations from which protected quantum gates can be designed. However, there is no experimental evidence for these non-Abelian anyons to date. In this paper, we study the $ν=2/k$ FQH-superconductor heterostructure and find the superconducting analogue of the $Z_k$ parafermion FQH state. Our main tool is the mapping of the FQH into coupled one-dimensional (1D) chains each with a pair of counter-propagating modes. We show that by inducing intra-chain pairing and charge preserving backscattering with identical couplings, the 1D chains flow into gapless $Z_{k}$ parafermions when $k< 4$. By studying the effect of inter-chain coupling, we show that every parafermion mode becomes massive except for the two outermost ones. Thus, we achieve a fractional topological superconductor whose chiral edge state is described by a $Z_k$ parafermion conformal field theory. For instance, we find that a $ν=2/3$ FQH in proximity to a superconductor produces a $Z_3$ parafermion superconducting state. This state is topologically indistinguishable from the non-Abelian part of the $ν=12/5$ Read-Rezay state. Both of these systems can host Fibonacci anyons capable of performing universal quantum computation through braiding operations.
description: 11 pages, 3 figures
title: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 12, Nr. 1 (1983)
Creators: name: Denkmalpflege In Baden-Württemberg – Nachrichtenblatt Der Landesdenkmalpflege
Publisher: name: University Library Heidelberg
Year: 2014

description: Inhalt
 Luftbildarchäologie in Baden-Württemberg...1-7
 Das ehemalige jüdische Gemeindezentrum in Hemsbach, Rhein-Neckar-Kreis...8-12
 Restaurierung eines römischen Badegebäudes in Merdingen, Kreis Breisgau-Hochschwarzwald...13-15
 [Zwei „Spitäler" des frühen 16. Jahrhunderts] Das „Neuhaus" des Heilig-Geist-Spitals in Ehingen, Alb-Donau-Kreis...16-19
 [Zwei „Spitäler" des frühen 16. Jahrhunderts] Das sogenannte Spital in Hayingen, Kreis Reutlingen...20-22
 Der römische Kastellturm in Waldmössingen, Stadt Schramberg...23-24
 [Nachruf] Hans Rolli...25
 Neuerscheinungen...26-28
 Mitteilungen ; Quellennachweis für die Abbildungen...28
 Veröffentlichungen des Landesdenkmalamtes
 Die Dienststellen des Landesdenkmalamtes
 Personalia...26
Surface energy coefficient of a N2LO Skyrme energy functional : a semiclassical Extended Thomas-Fermi approach
Creators: name: Proust, P.
name: Lallouet, Y.
name: Davesne, D.
name: Meyer, J.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We generalize to N2LO Skyrme functionals the semi-classical approach of Grammaticos and Voros in order to calculate the Extended Thomas Fermi expressions of the new densities and currents appearing at the N2LO level. Within a one dimensional symmetric semi infinite nuclear matter model and using a simple Fermi-like density profile, we obtain an easy-to-use formula for the surface energy including the contributions of the central, density-dependent and spin-orbit terms up to $\hbar^2$. Such a formula can be easily used as a first attempt to constrain the surface properties of new N2LO Skyrme parametrizations. The N2LO parametrization tested in this paper is shown to exhibit a shift (compared to a full Hartree-Fock calculation) which is quantitatively similar to the one obtained with the traditional Skyrme parametrizations.
description: 19 pages, 3 figures, to be published
A Database Management System for LAMDA Tomography Datasets
Creators: name: Izadifar, MohammadAli
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 460505
subject: Database systems

description: Abstract: X-ray Tomography is one of the well-known non-destructive methods for investigating the internal features of 3D objects. In Materials Science, this method is used for studying the internal defects, inclusions, microstructure, etc., of manufactured parts without cutting them. The images can be stacked together and reconstruct a digital version of the sample with all the details. An experienced person usually segments each image manually to identify the internal features, which is time-consuming and cumbersome. In recent years, AI has been employed for identifying those features after training with limited manually segmented images. Due to the enormous amount of data produced by imaging instruments and the everyday-growing number of AI architectures for image segmentation, the raw and processed data management and their relationship are challenging. This research proposes a database management system to control the tomography datasets and the AI architectures used for segmenting them
On refined Chern-Simons / topological string duality for classical gauge groups
Creators: name: Avetisyan, M. Y.
name: Mkrtchyan, R. L.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We present the partition function of the refined Chern-Simons theory on $S^3$ with arbitrary A,B,C,D gauge algebra in terms of multiple sine functions. For B and C cases this representation is novel. It allows us to conjecture duality to some refined and orientifolded versions of the topological string on the resolved conifold, and carry out the detailed identification of different contributions. The free energies for D and C algebras possess the usual halved contribution from the A theory, i.e. orientable surfaces, and contributions of non-orientable surfaces with one cross-cup, with opposite signs, similar as for the non-refined theories. However, in the refined case, both theories possess in addition a non-zero contribution of orientable surfaces with two cross-cups. In particular, we observe a trebling of the Kähler parameter, in the sense of a refinement and world-sheet (i.e. the number of cross-cups) dependent quantum shift. For B algebra the contribution of Klein bottles is zero, as is the case in the non-refined theory, and the one-cross-cup terms differ from the D and C cases. For the (refined) constant maps terms of these theories we suggest a modular-invariant representation, which leads to natural topological string interpretation. We also calculate some non-perturbative corrections.
description: Latex, 20 pages, analysis of the constant maps added
A study of knowledge, attitude and behavior with regard to food safety, in the Welsh hospitality and catering industry
Creators: name: Coleman, Philip
Publisher: name: Cardiff Metropolitan University
Year: 2022
Subjects: Food safety, traceability, certification and authenticity

description: Foodborne illnesses respresent a serious threat to health. The World Health Organisation (2000) recently passed a Resolution stating that "...foodborne illness associated with microbial pathogens, biotoxins and chemical contaminants in food present a serious threat to the health of millions of people in the world (p.1)". Overall notifications of foodborne illness and food poisoning have risen significantly and many outbreaks have been associated with the food industry. The Hospitality and Catering industry is of special concern because of it's size, diversity, individual characteristics, and direct interface with customers. This thesis focuses upon the Hospitality and Catering industry in Wales, a largely unexplored area of research. It applies an investigate approach to issues relating to the management and implementation of food safety in the industry across a range of industry sectors to be found in the Principality. Information was gathered by utlising a range of secondary and primary sources. Data collection instruments included questionnaires, structured interviews, and audit checklists and observations. These were administered by way of three discrete but interlinked primary data collection investigations. Both quantitative and qualitative data were obtained. Participating industry personnel included proprietors, managers and food handlers. Via a literature review, the key issues of knowledge, attitudes and behaviour related to food safety are discussed and evaluated within the contexts of the inherent characteristics of the Hospitality and Catering industry and food safety legislation. There three investigations are presented individually and the findings are consolidated in a synoptic discussion in relation to the Aims of the thesis. The findings indicated that within the Welsh Hospitality and Catering industry levels of knowledge and attitudes with regard to food safety and food safety legislation were variable and in some instances, unsatisfactory. In many instances, intentions to act in a positive manner towards the implementation of food safety precautions were not reflected in actual behaviour. It was further found that in establishments of all sizes and ownership categories, food handling practices were variable and in many cases, unsafe. Recommendations are made based upon the results obtained and discussed in this thesis.