cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Organizational determinants of information transfer in palliative care teams: A structural equation modeling approach
Creators: name: Schweighoffer, Reka
name: Blaese, Richard
name: Liebig, Brigitte
Publisher: name: Public Library of Science
Year: 2021
Subjects: subject: Palliative care
subject: Communications
subject: Allied health care professionals
subject: Health care providers
subject: Primary care
subject: Caregivers
subject: Health care facilities
subject: Nurses
subject: 610 - Medizin und Gesundheit

description: Several organizational factors facilitate or hinder information transfer in palliative care teams. According to past research, organizational factors that reduce information transfer include the inconsistent use of shared electronic patient files, frequent changes of healthcare staff, a lack of opportunities for personal exchange, and a lack of evaluation of collaborative processes. Insufficient information sharing between professionals can negatively impact patient safety, whereas studies have shown that some organizational factors improve collaboration between professionals and thus contribute to improved patient outcomes. The main purpose of this study is thus to investigate whether, and if so how, organizational factors contribute to successful information exchange in palliative care teams in Switzerland, while also accounting for the different care contexts of primary and specialized palliative care. A nationwide survey was aimed at medical professionals working in palliative care. In total, 379 participants (mean age = 49.8 years, SD = 10.3) were included in this study. Two main outcome variables were examined: healthcare providers’ satisfaction with information transfer in their team and their overall satisfaction with communication in their team. Hypotheses were tested by employing structural equation modeling. Findings revealed that the strongest predictors for effective information transfer in palliative care teams were sufficient opportunities for face-to-face meetings and supervision alongside feedback tools to improve collaborative practices and the application of guidelines and standards for collaboration. Face-to-face meetings were an even greater contributor to information transfer in specialized settings, whereas sharing the same work-based values with colleagues was considered more important in primary settings. Results from this study contribute to the existing literature elucidating how information transfer is facilitated in the field of palliative care. If proposed measures are implemented, this could possibly improve patient outcomes in palliative care. Furthermore, the findings can be useful for healthcare organizations and associations to make more efficient resource allocation decisions with the aim to optimize information transfer within the workforce.
Helmholtz Quality Indicators for Software and Data Products
Creators: name: Juckeland, Guido
Publisher: name: Zenodo
Year: 2025
Subjects: research software engineering
software quality
Helmholtz
research software publications

description: In February 2025, Guido Juckeland from Helmholtz-Zentrum Dresden-Rossendorf  gave a talk at the HiRSE Seminar Series about the Introduction of a quality indicator for research software publications. 

Abstract:

The Helmholtz Association is adding a new indicator for research data and research software publications to its reporting. A working group with members from all Helmholtz centers has been working on defining this new indicator and the Helmholtz general assembly has approved their suggestion in its fall meeting of 2024. In this talk the indicator as well as the ideas behind it and the methods to collect the information are introduced. The indicator is based on a maturity model looking at various aspects of a research software publication, thus also providing value to the authors of the software and research software researchers as it makes multiple aspects of research software as a scientific publication itself visible.
Additional file 3 of Tumor-derived small extracellular vesicles facilitate omental metastasis of ovarian cancer by triggering activation of mesenchymal stem cells
Creators: name: Gong, Lanqing
name: Li, Guoqing
name: Yi, Xiaoqing
name: Han, Qing
name: Wu, Qiulei
name: Ying, Feiquan
name: Shen, Lu
name: Cao, Ying
name: Liu, Xiaoli
name: Gao, Lingling
name: Li, Wenhan
name: Wang, Zehua
name: Cai, Jing
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 3.
title: Retinoide
Creators: name: Keller, Ulrike
Year: 2008

description: Die Regulation der Genexpression von Retinoiden ist ein umfangreich untersuchtes Beispiel für den direkten Einfluss von Nutrienten auf die Genexpression. Die wichtigsten bioaktiven Komponenten all-trans Retinsäure (RA) und 9-cis RA binden und aktivieren die Retinoidrezeptoren RAR und RXR. Diese liganden-abhängigen Transaktivierungsfaktoren gehören zu der Überfamilie der Steroidkernrezeptoren. Nach dem Durchlaufen von Konformationsänderungen, die ausgelöst werden durch das Binden von Liganden und das Rekrutieren von Coaktivatoren und Corepressoren, interagieren die RAR/RXR Heterodimere mit Retinsäure-Response elements (RAREs) in der Promoter-Region von Zielgenen und modulieren so die Gentranskription. Retinoide sind zudem in der Lage, die Genexpression unabhängig von RAREs durch ihre antagonistische Wirkung auf andere Transkriptionsfaktoren zu unterdrücken. Retinoide interagieren mit diversen intrazellulären Pathways und modulieren die Zellproliferation, Differenzierung und Morphogenese. Auch nach der Entwicklung bleiben sie essentiell für die Homöostasie adulter Vertebrata. Dieser Review gibt Einblick in den Retinoidmetabolismus, die Wirkmechanismen und ihre mögliche präventive Rolle auf dem Gebiet ernährungsassoziierter Erkrankungen.
Deep brain stimulation: emerging tools for simulation, data analysis, and visualization
Creators: name: Wårdell, Karin
name: Nordin, Teresa
name: Zsigmond, Peter
name: Westin, Carl-Fredrik
name: Hariz, Marwan
name: Vogel, Dorian
name: Hemm-Ode, Simone
Publisher: name: Frontiers
Year: 2022
Subjects: subject: deep brain stimulation (DBS)
subject: modeling and simulation
subject: neuroimaging
subject: probabilistic mapping
subject: connectivity
subject: intraoperative measurements
subject: visualization
subject: 500 - Naturwissenschaften

description: Deep brain stimulation (DBS) is a well-established neurosurgical procedure for movement disorders that is also being explored for treatment-resistant psychiatric conditions. This review highlights important consideration for DBS simulation and data analysis. The literature on DBS has expanded considerably in recent years, and this article aims to identify important trends in the field. During DBS planning, surgery, and follow up sessions, several large data sets are created for each patient, and it becomes clear that any group analysis of such data is a big data analysis problem and has to be handled with care. The aim of this review is to provide an update and overview from a neuroengineering perspective of the current DBS techniques, technical aids, and emerging tools with the focus on patient-specific electric field (EF) simulations, group analysis, and visualization in the DBS domain. Examples are given from the state-of-the-art literature including our own research. This work reviews different analysis methods for EF simulations, tractography, deep brain anatomical templates, and group analysis. Our analysis highlights that group analysis in DBS is a complex multi-level problem and selected parameters will highly influence the result. DBS analysis can only provide clinically relevant information if the EF simulations, tractography results, and derived brain atlases are based on as much patient-specific data as possible. A trend in DBS research is creation of more advanced and intuitive visualization of the complex analysis results suitable for the clinical environment.
Rapid sequestration of perovskite solar cell-derived lead in soil
Creators: name: Schmidt, Felix
name: Ledermann, Luca
name: Schäffer, Andreas
name: Snaith, Henry J.
name: Lenz, Markus
Publisher: name: Elsevier
Year: 2022
Subjects: subject: Perovskite solar cells
subject: Environmental impact
subject: Sequential extraction
subject: Environmental fate
subject: XANES
subject: Lead sequestration
subject: 600 - Technik, Medizin, angewandte Wissenschaften
subject: 500 - Naturwissenschaften

description: Efficient and stable perovskite solar cells rely on the use of Pb species potentially challenging the technologies’ commercialisation. In this study, the fate of Pb derived from two common perovskite precursors is compared to cationic lead in soil-water microcosm experiments under various biogeochemical conditions. The rapid and efficient removal of Pb from the aqueous phase is demonstrated by inductively coupled plasma mass spectrometry. Sequential soil extraction results reveal that a substantial amount of Pb is associated with immobile fractions, whereas a minor proportion of Pb may become available again in the long term, when oxygen is depleted (e.g. during water logging). X-ray absorption spectroscopy results reveal that the sorption of Pb on mineral phases represents the most likely sequestration mechanism. The obtained results suggest that the availability of leached Pb from perovskite solar cells is naturally limited in soils and that its adverse effects on soil biota are possibly negligible in oxic soils. All three Pb sources used behaved very similar in the experiments, wherefore we conclude that perovskite derived Pb will have a similar fate compared to cationic Pb, so that established risk assessment considerations for Pb remain legitimate.
Synchrotron-based technique: a new high resolution imaging of nervous system
Creators: name: Barbone, Giacomo
name: Ceresa, Cecilia
name: Monfrini, Marianna
name: Eckermann, Marina
name: Chiorazzi, Alessia
name: Canta, Annalisa
name: Bossi, Mario
name: Mittone, Alberto
name: Bravin, Alberto
name: Coan, Paola
name: Parlanti, Paola
name: Rigolio, Roberta
name: Cappello, Valentina
name: Gemmi, Mauro
name: Marmiroli, Paola
name: Cavaletti, Guido
Publisher: name: Firenze University Press
Year: 2017
Subjects: Imaging, synchrotron, phase contrast micro-tomography, nervous system

description: X-ray phase contrast micro-tomography (μPCI-CT) is a high resolution technique that can be used to investigate vascular and neurodegenerative disorders overcoming the limitations of the conventional imaging modalities. In fact, currently available neuroimaging techniques are based on sample-invasive imaging protocols involving dissections, staining or labeling of nervous system structures. On the other hand, μPCI-CT permits to visualize the spinal cord micro-vasculature, to detect single neuronal cells in the vertebral column and even cells infiltrating the nervous system in pathological conditions. These properties make μPCI-CT a potential powerful instrument in the study of vascular and neurodegenerative disorders as well as in the patient evaluation during medical treatment. Moreover, it would be a powerful instrument to localize in preclinical model of immune mediated diseases ectopic cells infiltrating the nervous system in a multifocal and unpredictable way. To optimize tissue fixation protocols for μPCI-CT analysis, several attempts were performed combining different protein and lipid fixation procedures and time points. The high-resolution synchrotron μPCI-CT setup allowed recognition of full-organ spinal cord anatomy of healthy rats, including anterior/posterior gray horns, the dorsal/ventral roots and ganglions, the central canal and the meninges, was clearly depicted. Superficial and deep vessels were visualized without need of any contrast-agent. At the highest resolution used, single neuronal cells perfused by surrounding vasculature were recognized allowing the detection of specific structure such as bundles of nerve fibers, single motor neurons and neuro-glial cells, cell bodies and axons as well as intra-cellular structure (i.e. cell nuclei and nucleoli). Moreover, in preclinical studies, the optimization of protocol for μPCI-CT allowed to localize ectopic infiltrating cells in nervous system organs in both mouse and rat models of Krabbe disease and Multiple Sclerosis which would allow a further accurate analysis of the areas and cell-parenchima fine interaction.
description: Italian Journal of Anatomy and Embryology, Vol. 122, No. 1 (Supplement) 2017
Probabilistic maps for deep brain stimulation – Impact of methodological differences
Creators: name: Nordin, Teresa
name: Vogel, Dorian
name: Osterlund, Erik
name: Johansson, Johannes
name: Fytagoridis, Anders
name: Blomstedt, Patric
name: Hemm-Ode, Simone
name: Wardell, Karin
Publisher: name: Elsevier
Year: 2022
Subjects: subject: Deep brain stimulation (DBS)
subject: Finite element method (FEM)
subject: Electric field simulation
subject: Essential tremor
subject: Improvement maps
subject: Side effects
subject: MRI template
subject: 600 - Technik, Medizin, angewandte Wissenschaften
subject: 500 - Naturwissenschaften

description: Background Group analysis of patients with deep brain stimulation (DBS) has the potential to help understand and optimize the treatment of patients with movement disorders. Probabilistic stimulation maps (PSM) are commonly used to analyze the correlation between tissue stimulation and symptomatic effect but are applied with different methodological variations. Objective To compute a group-specific MRI template and PSMs for investigating the impact of PSM model parameters. Methods Improvement and occurrence of dizziness in 68 essential tremor patients implanted in caudal zona incerta were analyzed. The input data includes the best parameters for each electrode contact (screening), and the clinically used settings. Patient-specific electric field simulations (n = 488) were computed for all DBS settings. The electric fields were transformed to a group-specific MRI template for analysis and visualization. The different comparisons were based on PSMs representing occurrence (N-map), mean improvement (M-map), weighted mean improvement (wM-map), and voxel-wise t-statistics (p-map). These maps were used to investigate the impact from input data (clinical/screening settings), clustering methods, sampling resolution, and weighting function. Results Screening or clinical settings showed the largest impacts on the PSMs. The average differences of wM-maps were 12.4 and 18.2% points for the left and right sides respectively. Extracting clusters based on wM-map or p-map showed notable variation in volumes, while positioning was similar. The impact on the PSMs was small from weighting functions, except for a clear shift in the positioning of the wM-map clusters. Conclusion The distribution of the input data and the clustering method are most important to consider when creating PSMs for studying the relationship between anatomy and DBS outcome.
Additional file 1 of Conducting co-creation for public health in low and middle-income countries: a systematic review and key informant perspectives on implementation barriers and facilitators
Creators: name: Longworth, Giuliana Raffaella
name: Erikowa-Orighoye, Oritseweyinmi
name: Anieto, Ebuka Miracle
name: Agnello, Danielle Marie
name: Zapata-Restrepo, Jorge Raul
name: Masquillier, Caroline
name: Giné-Garriga, Maria
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Science Policy
Biological Sciences not elsewhere classified
Cancer

description: Supplementary Material 1: Search strategy
Isotopic separation in mixed clusters of molecular hydrogen
Creators: name: Kolevski, Kiril M.
name: Hu, Jie-Ru
name: Boninsegni, Massimo
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We investigate mixed (50/50) clusters of parahydrogen and orthodeuterium at low temperature, by means of Quantum Monte Carlo simulations. Our results provide evidence of liquid-like behavior and partial isotopic separation in a cluster of 640 molecules, at temperature T=10 K. As the temperature is lowered below ~ 6 K, crystallization occurs, with no indication that the liquid phase is more resilient at low temperature in a mixed cluster. Isotopic separation is therefore predicted to take place at low temperature only through the slow process of molecular self-diffusion in a crystalline matrix.
description: Replaced with published version
Soil microbiomes divergently respond to heavy metals and polycyclic aromatic hydrocarbons in contaminated industrial sites
Creators: name: Yang, Zhen-Ni
name: Liu, Ze-Shen
name: Wang, Ke-Huan
name: Liang, Zong-Lin
name: Abdugheni, Rashidin
name: Huang, Ye
name: Wang, Run-Hua
name: Ma, Hong-Lin
name: Wang, Xiao-Kang
name: Yang, Mei-Ling
name: Zhang, Bing-Ge
name: Li, De-Feng
name: Jiang, Cheng-Ying
name: Liu, Shuang-Jiang
name: Corvini, Philippe
Publisher: name: Elsevier
Year: 2022
Subjects: subject: Soil microbiomes
subject: Electronic waste
subject: Coking plant
subject: Heavy metal
subject: Polycyclic aromatic hydrocarbons
subject: 500 - Naturwissenschaften

description: Contaminated sites from electronic waste (e-waste) dismantling and coking plants feature high concentrations of heavy metals (HMs) and/or polycyclic aromatic hydrocarbons (PAHs) in soil. Mixed contamination (HMs + PAHs) hinders land reclamation and affects the microbial diversity and function of soil microbiomes. In this study, we analyzed HM and PAH contamination from an e-waste dismantling plant and a coking plant and evaluated the influences of HM and PAH contamination on soil microbiomes. It was noticed that HMs and PAHs were found in all sites, although the major contaminants of the e-waste dismantling plant site were HMs (such as Cu at 5,947.58 ± 433.44 mg kg−1, Zn at 4,961.38 ± 436.51 mg kg−1, and Mn at 2,379.07 ± 227.46 mg kg−1), and the major contaminants of the coking plant site were PAHs (such as fluorene at 11,740.06 ± 620.1 mg kg−1, acenaphthylene at 211.69 ± 7.04 mg kg−1, and pyrene at 183.14 ± 18.89 mg kg−1). The microbiomes (diversity and abundance) of all sites were determined via high-throughput sequencing of 16S rRNA genes, and redundancy analysis was conducted to investigate the relations between soil microbiomes and contaminants. The results showed that the microbiomes of the contaminated sites divergently responded to HMs and PAHs. The abundances of the bacterial genera Sulfuritalea, Pseudomonas, and Sphingobium were positively related to PAHs, while the abundances of the bacterial genera Bryobacter, Nitrospira, and Steroidobacter were positively related to HMs. This study promotes an understanding of how soil microbiomes respond to single and mixed contamination with HMs and PAHs.
Scanning Electron Microscopy in forensic investigations: More views from more applications
Creators: name: Basso, Petra
name: Reguzzoni, Marcella
name: Protasoni, Marina
name: Congiu, Terenzio
name: Quacci, Daniela
Publisher: name: Firenze University Press
Year: 2017
Subjects: Scanning Electron Microscopy; Forensic Science

description: The purpose of this presentation is to expand and highlight the range of applications of scanning electron microscopy to forensic science, following the overview which was shown last year at the LXX SIAI Congress. All examples shown of forensic uses of SEM were carried out over the last few years at the Human Morphology Laboratory of the University of Insubria. These studies include: - The identification and characterization of different toolmarks found on human bones. Some toolmarks have a distinctive morphology and allow a reliable identification of the weapon or instrument used. For this purpose, we will illustrate a few examples of dismemberment with different types of saw and will show the peculiar bone patterns left by different cutting edges (knives, axes, cutters ...); - The examination of human tissues and of medical devices (catheters etc.) for the early detection and identification of slow-growing microorganisms (e.g. some fungi). The diagnosis of these microorganisms would have otherwise required molecular biology techniques, which are not only expensive but also not always available or applicable in the field of forensics (for instance, when the specimen is inadequate for external contaminations or is into a state of conservation far from optimal), or conventional cultures in vitro, which require much longer times and may be easily spoiled by inopportune drug administration; - The use of scanning electron microscopy and of X-ray spectroscopy as auxiliary and “creative” tools to discover mystifications and frauds against insurance companies.
description: Italian Journal of Anatomy and Embryology, Vol. 122, No. 1 (Supplement) 2017
Ultrastructural modifications of human meniscus under different conditions
Creators: name: Battistelli, Michela
name: Favero, Marta
name: Trisolino, Giovanni
name: Dallari, Dante
name: Filardo, Giuseppe
name: Grigolo, Brunella
name: Falcieri, Elisabetta
name: Olivotto, Eleonora
Publisher: name: Firenze University Press
Year: 2017
Subjects: Human Meniscus; Transmission Electron Microscopy; Ederly; Trauma; OA

description: Human meniscus presents two cell populations [1]. The main cell type present in its inner and middle part is the fibrochondrocyte, a round or oval shaped cell, while in outer zone fibroblast-like cells within a dense connective tissue [2] are mostly observable. The aim of this work is to study a variety of pathological conditions. We have analized samples of meniscus obtained from 3 multiorgan donors (63 median age, years), 5 patients with traumatic meniscal tear (40 median age, years) and from 3 patients undergoing total knee replacement for osteoartritis (OA) (73 median age, years). In elderly menisci we observed a progression of chromatin margination, and a partial cytoplasmic organelle conservation, but for the presence of occasional autophagic vacuoles. Both after trauma and in OA, an increasing chromatin condensation, organelle degeneration and cytoplasmic vacuolization appear. In OA, similarly to elderly, autophagic vacuoles, which probably represent a cellular self-protection mechanism, appeared in the cytoplasm. The most evident ultrastructural changes have been observed when intervention takes place long time after trauma. In this case a high chromatin condensation, a large cytoplasmic vacuolization with degeneration of organelles and several necrotic cells appear. Calcification areas occur in all conditions. In particular, specimens from traumatic menisci have a structure similar to OA ones, especially if trauma has not been surgically repaired  at appropriate times. In all there is disorganization of collagen fibers, and their replacement with proteoglycans. We can conclude that trauma and OA induce an increasing meniscal degeneration, comparable to physiological aging. When surgery takes place long time after trauma we observed most evident menisci degeneration. In all pathological conditions apoptotic like features appeared [3].
description: Italian Journal of Anatomy and Embryology, Vol. 122, No. 1 (Supplement) 2017
Advancing Organic Electronics: Polymorphism and Molecular Orientation
Creators: name: VU, VAN DOAN
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 401609
subject: Polymers and plastics
classificationCode: 400910
subject: Photovoltaic devices (solar cells)
classificationCode: 401802
subject: Molecular and organic electronics
classificationCode: 511003
subject: Synchrotrons

description: Polymorphism and molecular orientation, which are well known to be sensitive to processing conditions and post-deposition treatments, have considerable influence on the charge transport properties and performance of organic electronic devices. Through this project, significant advances in understanding polymorphism and molecular orientation in naphthalene diimide-based copolymers have been made with the use of lab- and synchrotron-based techniques, along with the implications for charge transport properties in organic electronic devices. The findings from this thesis will advance microstructural control and assist in the rational design of conjugated materials for high performance organic electronics.
PI3Kα-selective inhibitor alpelisib (BYL719), may be effective as anticancer agents in Rhabdomyosarcoma
Creators: name: Bavelloni, Alberto
name: Piazzi, Manuela
name: Ramazzotti, Giulia
name: Fiume, Roberta
name: Blalock, William
name: Faenza, Irene
Publisher: name: Firenze University Press
Year: 2017
Subjects: Rhabdomyosarcoma; PI3K/Akt pathway; cancer

description: Rhabdomyosarcoma (RMS) is a highly malignant and metastatic pediatric cancer that arises from the skeletal muscle. Recent studies have identified an important role of AKT signaling in RMS progression. This suggests targeting components of the PI3K/Akt pathway may be an effective therapeutic strategy. Here, we investigated the in vitro activity of the class I PI3K inhibitors [1] in human rhabdomyosarcoma cell lines (embryonal rhabdomyosarcoma RD and A204, alveolar rhabdomyosarcoma SJCRH30). We used a panel of four compounds which specifically target PI3K isoforms including the PI3Kα-selective (p110α ) inhibitor alpelisib BYL719, currently in clinical development by Novartis Oncology, the p110β TGX-221 inhibitor, the p110γ CZC24832, the p110δ CAL-101inhibitor and the dual p110α/p110δ inhibitor AZD8835. The effects of single drugs and of several drug combinations were analyzed to assess cytotoxicity by MTT assays, cell cycle by flow cytometry , apoptosis by caspase 3/7 assay and Western blot, as well as the phosphorylation status of the pathway. BYL719 treatment resulted in G1 phase cell cycle arrest and apoptosis. BYL719 administered in combination with CAL-101, for 48 h and 72h, decreased cell viability and induced apoptosis in a marked synergistic manner. Taken together, our findings indicate that BYL719, either alone or in combination with p110δ CAL-101inhibitor, may be an efficient treatment for human rhabdomyosarcoma cells that have aberrant upregulation of the PI3K signaling pathway for their proliferation and survival.
description: Italian Journal of Anatomy and Embryology, Vol. 122, No. 1 (Supplement) 2017
Binocular advantages in reading revisited. Attenuating effects of individual horizontal heterophoria
Creators: name: Jainta, Stephanie
name: Joss, Joëlle
Publisher: name: Bern Open Publishing
Year: 2019
Subjects: subject: binocular coordination
subject: binocular advantages
subject: eye movement
subject: heterophoria
subject: optometric tests
subject: 610 - Medizin und Gesundheit

description: Reading with two eyes necessitates efficient processes of binocular vision, which provide a single percept of the text. These processes come with a binocular advantage: binocular reading shows shorter average fixation durations and sentence reading times when compared to monocular reading. A couple of years ago, we showed for a small sample (N=13) that binocular advantages critically relate to the individual heterophoria (the resting state of vergence). In the present, large-scale replication we collected binocular eye movements (Eyelink II) for 94 participants who read 20 sentences monocularly and 20 sentences binocularly. Further, individual heterophorias were determined using three different optometric standards: objective eye tracking (EyeLink II at 60 cm), Maddox wing test (at 30 cm) and measures following the “Guidelines for the application of the Measuring and Correcting Methodology after H.-J. Haase” (MCH; at 6 m). Binocular eye movements showed typical pattern and we replicated (1) binocular advantages of about 25 ms for average fixation durations and (2) a reduction in binocular advantages when heterophoria increased – but only when heterophoria was identified by EyeLink II or Maddox wing measures; MCH measures of heterophoria did not affect binocular advantages in reading. For large heterophorias binocular reading even turned into a disadvantage. Implications for effect estimations and optometric testing will be discussed.
Plasma redox response of Sicilian Opuntia Ficus Indica juice in young physically active women
Creators: name: Bellafiore, Marianna
name: Pintaudi, Anna Maria
name: Cataldo, Angelo
name: Cerasola, Dario
name: Attanzio, Alessandro
name: Battaglia, Giuseppe
name: Bianco, Antonino
name: Palma, Antonio
Publisher: name: Firenze University Press
Year: 2017
Subjects: Antioxidant supplementation; oxidative stress; redox balance; indicaxanthin

description: It is known amateur female athletes show an altered redox status [1] and the consumption of Opuntia Ficus Indica (OFI) decreases oxidative stress (OS) in healthy humans [2]. Therefore, the aim of this study was to investigate whether the supplementation with Sicilian OFI juice affected plasma redox balance following a maximal effort test in young physically active women 			. This study was randomized, double blind, placebo controlled and crossover design. Eight women (23.25±2.95 years old, weight of 54.13±9.05 kg, height of 157.75±0.66 cm and BMI of 21.69±0.66 kg/m2) were randomly divided into 2 groups and each group was supplied with either 50 ml OFI, diluted to 170 ml with water, or 170 ml Placebo containing the same concentration of fruit juice ingredients except for Vitamin C and indicaxanthin. They consumed OFI or Placebo every day for 3 days before of effort test on cycle ergometer and continued to take it for 2 consecutive days after testing. Blood samples were taken before and after the effort test without supplementation (baseline), pre- and post-test, 24 h and 48 h post-test with OFI or Placebo supplementation. H2O2 levels and total antioxidant capacity (PAT) were measured with photometer and resonance Raman spectroscopy [1,2]. The differences within and between groups were calculated with ANOVA analysis and considered significant with P<0.05. OFI group showed a significant lower quantity of H2O2 than Placebo group after the effort test. PAT levels of OFI group were significantly higher than pre/post those of baseline and 48 h post-test of Placebo group. In conclusion, OFI supplementation might to be used to restore redox balance after intense exercises in moderately trained women.
description: Italian Journal of Anatomy and Embryology, Vol. 122, No. 1 (Supplement) 2017
Relating asthenopic symptoms to optometric measures and parameters of binocular vision
Creators: name: Joss, Joëlle
name: Jainta, Stephanie
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2022
Subjects: subject: asthenopic symptoms
subject: binocular coordination
subject: optometric tests
subject: 610 - Medizin und Gesundheit

description: Asthenopic symptoms are related to heterophoria and problems of binocular vision. In a recent paper, we showed that vergence drift and fixation durations are related to symptoms (CISS-questionnaire), but optometric measures such as heterophoria, vergence or accommodative facility, AC/A-ratio or NPC did not significantly add to the explained variance of asthenopia. We re-analysed our data, in which binocular eye movements were recorded (EyeLink II) for 64 participants, and linear regression analyses related all parameters of binocular coordination (objective heterophoria, vergence drift, saccade disconjugacy, fixation disparity and fixation duration), and the above-mentioned optometric tests to 4 symptoms factors (eye comfort, reading process, image quality and fatigue), which we identified by a factor analysis of the CISS-questionnaire. Objective heterophoria and fixation duration predicted 20% of the variance in symptoms concerning the reading process (factor 2). Furthermore, fixation duration seems to be slightly, but not significantly, related to symptoms addressing fatigue (factor 4), whereas optometric tests are not significantly related to any asthenopia factor. Overall, objective measures during reading relate to asthenopic symptoms, however the lack of asthenopic symptoms prediction by daily optometric parameters is still unexplained. Therefore, further research is needed to find out suited optometric parameters to infer asthenopic symptoms.
Additional file 2 of Conducting co-creation for public health in low and middle-income countries: a systematic review and key informant perspectives on implementation barriers and facilitators
Creators: name: Longworth, Giuliana Raffaella
name: Erikowa-Orighoye, Oritseweyinmi
name: Anieto, Ebuka Miracle
name: Agnello, Danielle Marie
name: Zapata-Restrepo, Jorge Raul
name: Masquillier, Caroline
name: Giné-Garriga, Maria
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Science Policy
Biological Sciences not elsewhere classified
Cancer

description: Supplementary Material 2: Data Extraction Template
Supplementary document for Computational 3D microscopy with optical coherence refraction tomography - 5801619.pdf
Creators: name: Zhou, Kevin
name: McNabb, Ryan
name: Qian, Ruobing
name: Degan, Simone
name: Dhalla, Al-Hafeez
name: Farsiu, Sina
name: Izatt, Joseph
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering
subject: 111302 Optical Technology
subject: FOS: Clinical medicine

description: Supplemental document
Additional file 3 of Conducting co-creation for public health in low and middle-income countries: a systematic review and key informant perspectives on implementation barriers and facilitators
Creators: name: Longworth, Giuliana Raffaella
name: Erikowa-Orighoye, Oritseweyinmi
name: Anieto, Ebuka Miracle
name: Agnello, Danielle Marie
name: Zapata-Restrepo, Jorge Raul
name: Masquillier, Caroline
name: Giné-Garriga, Maria
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Science Policy
Biological Sciences not elsewhere classified
Cancer

description: Supplementary Material 3: Interviewee details
Individuelle Herausforderungen und Kompetenzen bei mobil-flexibler Arbeit
Creators: name: Grob, Samuel
Publisher: name: Hochschule für Angewandte Psychologie FHNW
Year: 2022
Subjects: Mobil-flexible Arbeit
Home Office
individuelle Herausforderungen
individuelle Kompetenzen
Selbstführung
Training

description: Je intensiver das Modell mobil-flexibler Arbeit genutzt wird, desto stärkere Selbstkompetenzen sind notwendig. Will von einem Unternehmen die mobil-flexible Arbeit gefördert werden, lohnt es sich, ein Angebot für das Trainieren von Selbstkompetenzen zu schaffen. In vorliegender Arbeit wird in einem IT-Unternehmen untersucht, wie sich die beruflichen Anforderungen mit einem organisationalen Wechsel zur mobil-flexiblen Arbeit verändern. Darauf aufbauend wird herausgearbeitet, welche Kompetenzen benötigt werden, sodass mit einer erhöhten Zufriedenheit und einem gesteigerten Leistungsempfinden mobil- flexibel gearbeitet werden kann. Ressourcen und Herausforderungen verändern sich bei mobil-flexibler Arbeit. Dabei ist die eingeschränkt verfügbare soziale Ressource die grösste Herausforderung. Um diese Herausforderung zu puffern sind höhere Selbstkompetenzen notwendig. Als ausschlaggebend gilt dabei die Selbstführung. Um die Selbstführung zu trainieren, werden im Rahmen dieser Masterthesis Workshops mit 32 Teilnehmenden durchgeführt. Die anschliessende Evaluation zeigt, dass sich diese betriebliche Intervention lohnt, um einen Wechsel in die mobil-flexible Arbeit auf individueller Ebene zu unterstützen, denn auf diese Weise kann die Selbstführung, das Leistungsempfinden sowie die Arbeitszufriedenheit gefördert werden.
Aerobic Fitness protects from Atherosclerotic Cardiovascular Risk Paralympic Athletes with a Locomotor Impairment
Creators: name: Bernardi, Marco
name: Parisi, Fabiana
name: Corsi, Loretta
name: Delussu, Anna Sofia
name: Lanzano, Riccardo
name: Alviti, Federica
name: Squeo, Maria Rosaria
name: Adami, Paolo Emilio
name: Guerra, Emanuele
name: Magaudda, Ludovico
name: Spataro, Antonio
name: Pelliccia, Antonio
Publisher: name: Firenze University Press
Year: 2017

description: Aim: This study, carried out on Paralympic athletes (PA) with a locomotor impairment (LI), was aimed at: 1. assessing the prevalence of atherosclerotic cardiovascular disease (ACVD) risk factors (RF) in PA with either a spinal cord injury (PA-SCI) or other (different from SCI) LI (PA-OLI); 2. evaluating the hypothesis that aerobic fitness (oxygen uptake peak - VO2peak) was inversely related to ACVD RF. Methods: A total of 135 male PA (72 PA-SCI, 28 PA with lower limb amputation, 12 PA with a cerebral palsy/brain injury, 7 PA with poliomyelitis, 9 PA with other neurological disorders and 7 PA with other orthopedic disorders) were screened through anthropometric and blood pressure (BP) measurements, laboratory blood tests and graded cardiopulmonary maximal exercise test, to estimate both an ACVD-RF score and VO2peak. The ACVD-RF score was assessed summing 1 point for each of the following RF: obesity –OB- (BMI≥30 or waist circumference ≥102 cm), hypertension –HT- (systolic BP ≥ 140 mm Hg and diastolic BP ≥ 90 mm Hg), dyslipidemia -DL- (total Cholesterol -C- ≥200 mg·dl-1 or LDL-C ≥130 mg·dl-1 or HDL-C <40mg·dl-1), impaired fasting glucose -IG- (fasting plasma glucose ≥100 mg·dl-1) and subtracting 1 point when serum HDL-C was higher than 60 mg·dl-1. Results: Prevalence of OB, HT, DL, IG and high HDL-C were equal to 5.9% and 3.2%, 13.9% and 14.3%, 58.3% and 49%, 29.2% and 34.9%, 27.8% and 17.4%, in PA-SCI and PA-OLI, respectively. Based on the ACVD RF, 3 groups were formed: group 1 (RF≤0, N=54), group 2 (RF=1, N=41), group 3 (RF≥2, N=40). VO2peak was equal to 37.9±14.71 ml·kg-1·min-1, 30.9±9.13 ml·kg-1·min-1 and 24.1±5.50 ml·kg-1·min-1 in the PA of groups 1, 2 and 3, respectively. Conclusions: Being VO2peak inversely related to groups of ACDR RF, high aerobic fitness provides a protective effect on ACVD morbidity in PA.
description: Italian Journal of Anatomy and Embryology, Vol. 122, No. 1 (Supplement) 2017
title: Mittelalterliche Landwirtschaft im Vergleich
Creators: name: Heuritsch, Claudia
Year: 2008

description: Die vorliegende Arbeit geht der Fragestellung nach dem europäischen Sonderweg nach. Dazu wird die mittelalterliche westeuropäische Landwirtschaft den Agrarwirtschaften des Byzantinischen Reichs und des islamischen Raums vergleichend gegenübergestellt. Als Ausgangspunkt dienen die frühmittelalterlichen Agrarrevolutionen Westeuropas und des islamischen Raums und das traditionelle Byzanz. Naturräumliche und historische Faktoren beeinflussen dabei die Entwicklungen in den einzelnen Regionen ebenso wie Viehzucht, Agrarverfassung und Arbeitsteilung. Im letzten Teil werden Möglichkeiten und Grenzen der verglichenen Agrarwirtschaften im ausgehenden Mittelalter aufgezeigt. Es zeigt sich, dass sich Westeuropa, Byzanz und islamischer Raum, trotz gemeinsamer landwirtschaftlicher Grundlagen während des Römischen Reichs, seit dem Frühmittelalter in unterschiedliche Richtungen bewegt haben. Die europäische Agrarrevolution weist anfangs nicht dieselbe Dynamik auf wie die islamische, sie schafft jedoch eine Grundlage, die sich in Europa als dauerhaft und ausbaufähig erweist und nachhaltig die gesellschaftliche Entwicklung beeinflusst.
Temperature and differential emission measure evolution of a limb flare on 13 January 2015
Creators: name: Bröse, Malte
name: Warmuth, Alexander
name: Sakao, Taro
name: Su, Yang
Publisher: name: arXiv
Year: 2024
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Spatially unresolved observations show that the cooling phase in solar flares can be much longer than theoretical models predict. It has not yet been determined whether this is also the case for different subregions within the flare structure. We aim to investigate whether or not the cooling times, which are observed separately in coronal loops and the supra-arcade fan (SAF), are in accordance with the existing cooling models, and whether the temperature and emission measure of supra-arcade downflows (SADs) are different from their surroundings. We analysed the M5.6 limb flare on 13 January 2015 using SDO/AIA observations. We applied a differential emission measure (DEM) reconstruction code to derive spatially resolved temperature and emission measure maps, and used the output to investigate the thermal evolution of coronal loops, the SAF, and the SADs. In the event of 13 January 2015,the observed cooling times of the loop arcade and the SAF are significantly longer than predicted by the Cargill model, even with suppressed plasma heat conduction. The observed SADs show different temperature characteristics, and in all cases a lower density than their surroundings. In the limb flare event studied here, continuous heating likely occurs in both loops and SAF during the gradual flare phase and leads to an extended cooling phase.
Additional file 4 of Conducting co-creation for public health in low and middle-income countries: a systematic review and key informant perspectives on implementation barriers and facilitators
Creators: name: Longworth, Giuliana Raffaella
name: Erikowa-Orighoye, Oritseweyinmi
name: Anieto, Ebuka Miracle
name: Agnello, Danielle Marie
name: Zapata-Restrepo, Jorge Raul
name: Masquillier, Caroline
name: Giné-Garriga, Maria
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Science Policy
Biological Sciences not elsewhere classified
Cancer

description: Supplementary Material 4: Guiding interview questions
Factsheets Nachbarschaft
Creators: name: Beck, Sebastian
name: Becker, Anna
name: Drilling, Matthias
name: Oehler, Patrick
name: Schnur, Olaf
name: Tappert, Simone
Publisher: name: vhw Dienstleistung
Year: 2021
Subjects: subject: 360 - Soziale Probleme, Sozialdienste, Versicherungen

description: Die Factsheets widmen sich kompakt und praxisnah verschiedenen Aspekten von Nachbarschaft. Aus der wissenschaftlichen Beschäftigung mit dem Thema ist die Idee entstanden, eine alltagsbezogene Handreichung zu entwickeln, die fest auf wissenschaftlichem Boden verankert ist. Das Team um Matthias Drilling, Simone Tappert, Patrick Oehler und Olaf Schnur arbeitet in verschiedenen Kontexten zu Nachbarschafts- und Quartiersthemen. Sebastian Beck und Anna Becker haben das Team beim Verfassen der Factsheets zu den Themen Nachbarschaftsinitiativen bzw. Digitale Nachbarschaften ergänzt.
Additional file 1 of Simulation of dual-purpose chicken breeding programs implementing gene editing
Creators: name: Chuang, Edward Y. S.
name: Wellmann, Robin
name: Meijboom, Franck L. B.
name: Tetens, Jens
name: Bennewitz, Jörn
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Changes in average true genetic values (TGV) for egg production in different scenarios and different lines. The change in true genetic values for egg production (until 1, 10, 20, and 40 generations) compared to the -100 generation. Table S2. Changes in average true genetic values (TGV) for meat production in different scenarios and different lines. The change in true genetic values for meat production (until 1, 10, 20, and 40 generations) compared to the -100 generation. Table S3. Changes in average true genetic values (TGV) for overall health in different scenarios and different lines. The change in true genetic values for overall health (until 1, 10, 20, and 40 generations) compared to the -100 generation. Table S4. Changes in average true genetic values (TGV) changes of (dual-purpose) trait index in different scenarios and different lines. The change in true genetic values for the (dual-purpose) trait index (until 1, 10, 20, and 40 generations) compared to the -100 generation.
Additional file 2 of Simulation of dual-purpose chicken breeding programs implementing gene editing
Creators: name: Chuang, Edward Y. S.
name: Wellmann, Robin
name: Meijboom, Franck L. B.
name: Tetens, Jens
name: Bennewitz, Jörn
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2. Proofs for the conditional distributions of EBV and for the variance of the estimate of an SNP-effect.
NotebookLM: Um co-piloto inteligente na jornada de pesquisa
Creators: name: Santillan-Aldana, Julio
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Inteligência artificial
subject: Artificial intelligence
subject: Inteligencia artificial

description: Apresenta as principais características do Google NotebookLM, uma ferramenta de inteligência artificial que permite aos usuários criar, resumir e gerenciar anotações e documentos, incluindo a geração de resumos, guias de estudo, perguntas e podcasts a partir de fontes carregadas.
description: Presenta las principales características de Google NotebookLM, una herramienta de inteligencia artificial que permite a los usuarios crear, resumir y gestionar apuntes y documentos, incluida la generación de resúmenes, guías de estudio, preguntas y podcasts a partir de fuentes cargadas.
description: It presents the main features of Google NotebookLM, an artificial intelligence tool that allows users to create, summarize and manage notes and documents, including the generation of summaries, study guides, questions and podcasts from uploaded sources.
CROSS - CULTURAL ANALYSIS OF BODY PART IDIOMS IN  ENGLISH AND UZBEK.
Creators: name: Davlatova, Kamolaxon
Publisher: name: Zenodo
Year: 2024

description: Frazelogiya – barqaror birikmalar, frazeologizmlar va tayyor iboralarni o‘rganadigan tilshunoslik sohasi bo‘lib, til va madaniyat o‘rtasidagi o‘zaro munosabatni ochib beradi. Ushbu iboralar ko‘pincha madaniy qadriyatlar, tarixiy tajribalar va jamiyatning umumiy e’tiqodlarini o‘zida mujassam etadi. Ayniqsa, tana a’zolariga oid frazeologizmlar madaniy qadriyatlar, ijtimoiy me’yorlar va insoniy tajribalar haqida muhim ma’lumotlarni aks ettiradi. Tana a’zolari bilan bog‘liq frazeologizmlar turli madaniyatlarda tilning keng tarqalgan elementi bo‘lib, inson tanasining kundalik hayotimizdagi ahamiyatini va turli jamiyatlar qanday qilib alohida tana a’zolari atrofida ma’nolar shakllantirganini ko‘rsatadi.Ushbu maqola ingliz va o‘zbek tillaridagi tana a’zolari bilan bog‘liq frazeologizmlarni tahlil qiladi, ularning o‘xshashlik va farqlarini ko‘rsatib, ular orqali ifodalanadigan madaniyatlar haqida fikrlar bildiradi. Ushbu maqola ingliz va o‘zbek tillaridagi tana a’zolariga oid frazeologizmlarni taqqosiy tahlil qilishni maqsad qilgan bo‘lib, ularning kelib chiqishi, o‘xshashlik va farqlarini o‘rganadi.
Die lernende und sich bildende Gruppe
Creators: name: Beywl, Wolfgang
name: Fengler, Janne
Publisher: name: ZIEL
Year: 2022
Subjects: subject: Weiterbildung
subject: Fortbildung
subject: Wissenschaftliche Weiterbildung
subject: Bildung
subject: Lernen
subject: 370 - Erziehung, Schul- und Bildungswesen

description: Im Mittelpunkt des vorliegenden Hefts steht das Gruppenlernen. Dabei wird das individuelle Lernen in Gruppen nur peripher angesprochen. Zentraler Gegenstand des Schwerpunktthemas ist das Lernen von Gruppen. Damit meinen wir den Prozess überindividuellen Lernens, den Gruppen durchlaufen, sowie dessen Niederschlag als Resultat im kollektiven Denken oder Handeln dieser Gruppen. Aus systemischer Sicht steht dies zwischen dem individuellen Lernen und dem organisationalen Lernen – und ist damit auch relevant für die Organisationsentwicklung.