cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On the Risks of Collecting Multidimensional Data Under Local Differential Privacy
Creators: name: Arcolezi, Héber H.
name: Gambs, Sébastien
name: Couchot, Jean-François
name: Palamidessi, Catuscia
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: The private collection of multiple statistics from a population is a fundamental statistical problem. One possible approach to realize this is to rely on the local model of differential privacy (LDP). Numerous LDP protocols have been developed for the task of frequency estimation of single and multiple attributes. These studies mainly focused on improving the utility of the algorithms to ensure the server performs the estimations accurately. In this paper, we investigate privacy threats (re-identification and attribute inference attacks) against LDP protocols for multidimensional data following two state-of-the-art solutions for frequency estimation of multiple attributes. To broaden the scope of our study, we have also experimentally assessed five widely used LDP protocols, namely, generalized randomized response, optimal local hashing, subset selection, RAPPOR and optimal unary encoding. Finally, we also proposed a countermeasure that improves both utility and robustness against the identified threats. Our contributions can help practitioners aiming to collect users' statistics privately to decide which LDP mechanism best fits their needs.
description: Accepted at VLDB 2023. Version of record at https://doi.org/10.14778/3579075.3579086
Rundschreiben des Papstes zum 1400. Todestag des Hl. Benedikt "Fulgens Radiatur"
Creators: name: Pius XII., Papst
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 1 Nr. 9 (1946): Herder Korrespondenz, Band 1, Heft 9
The Paternal Gene of the DDK Syndrome Maps to the Schlafen Gene Cluster on Mouse Chromosome 11
Creators: name: Bell, T. A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: The DDK syndrome is an early embryonic lethal phenotype observed in crosses between females of the DDK inbred mouse strain and many non-DDK males. Lethality results from an incompatibility between a maternal DDK factor and a non-DDK paternal gene, both of which have been mapped to the Ovum mutant (Om) locus on mouse chromosome 11. Here we define a 465-kb candidate interval for the paternal gene by recombinant progeny testing. To further refine the candidate interval we determined whether males from 17 classical and wild-derived inbred strains are interfertile with DDK females. We conclude that the incompatible paternal allele arose in the Mus musculus domesticus lineage and that incompatible strains should share a common haplotype spanning the paternal gene. We tested for association between paternal allele compatibility/incompatibility and 167 genetic variants located in the candidate interval. Two diallelic SNPs, located in the Schlafen gene cluster, are completely predictive of the polar-lethal phenotype. These SNPs also predict the compatible or incompatible status of males of five additional strains.
Tests of a Novel Design of Resistive Plate Chambers
Creators: name: Bilki, B.
name: Corriveau, F.
name: Freund, B.
name: Neubüser, C.
name: Onel, Y.
name: Repond, J.
name: Schlereth, J.
name: Xia, L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A novel design of Resistive Plate Chambers (RPCs), using only a single resistive plate, is being proposed. Based on this design, two large size prototype chambers were constructed and were tested with cosmic rays and in particle beams. The tests confirmed the viability of this new approach. In addition to showing an improved single-particle response compared to the traditional 2-plate design, the novel chambers also prove to be suitable for calorimetric applications.
Analysis of the Proteins Involved in the in Vivo Repair of Base-Base Mismatches and Four-Base Loops Formed During Meiotic Recombination in the Yeast Saccharomyces cerevisiae
Creators: name: Stone, J. E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: DNA mismatches are generated when heteroduplexes formed during recombination involve DNA strands that are not completely complementary. We used tetrad analysis in Saccharomyces cerevisiae to examine the meiotic repair of a base–base mismatch and a four-base loop in a wild-type strain and in strains with mutations in genes implicated in DNA mismatch repair. Efficient repair of the base–base mismatch required Msh2p, Msh6p, Mlh1p, and Pms1p, but not Msh3p, Msh4p, Msh5p, Mlh2p, Mlh3p, Exo1p, Rad1p, Rad27p, or the DNA proofreading exonuclease of DNA polymerase δ. Efficient repair of the four-base loop required Msh2p, Msh3p, Mlh1p, and Pms1p, but not Msh4p, Msh5p, Msh6p, Mlh2p, Mlh3p, Exo1p, Rad1p, Rad27p, or the proofreading exonuclease of DNA polymerase δ. We find evidence that a novel Mlh1p-independent complex competes with an Mlhp-dependent complex for the repair of a four-base loop; repair of the four-base loop was affected by loss of the Mlh3p, and the repair defect of the mlh1 and pms1 strains was significantly smaller than that observed in the msh2 strain. We also found that the frequency and position of local double-strand DNA breaks affect the ratio of mismatch repair events that lead to gene conversion vs. restoration of Mendelian segregation.
Deviation of geodesics and particle trajectories in a gravitational wave of the Bianchi type VI universe
Creators: name: Osetrin, Konstantin
name: Osetrin, Evgeny
name: Osetrina, Elena
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 83C10, 83C35

description: For the Bianchi type VI universe, exact solutions of the equation of geodesic deviation in a strong primordial gravitational wave in a privileged coordinate system are obtained. The solutions refer to Shapovalov's gravitational-wave models of spacetime and allow the existence of complete integrals of the Hamilton-Jacobi equation for test particles. For all the solutions obtained, the analytical form of the tidal acceleration vector in a strong primordial gravitational wave is obtained. An explicit form of the coordinate transformation, an explicit form of the metric of the primordial gravitational wave of the Bianchi type VI universe, and the form of the tidal acceleration vector in the laboratory synchronous coordinate system are obtained. The synchronous coordinate system is associated with a freely falling observer and allows the observer to separate time and spatial coordinates, as well as to synchronize time at different points in space. The presented mathematical approach can be applied both in the general theory of relativity and in modified theories of gravity.
description: 26 pages
Possible points of blow-up in chemotaxis systems with spatially heterogeneous logistic source
Creators: name: Black, Tobias
name: Fuest, Mario
name: Lankeit, Johannes
name: Mizukami, Masaaki
Publisher: name: arXiv
Year: 2022
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35B44, 35K55, 92C17

description: We discuss the influence of possible spatial inhomogeneities in the coefficients of logistic source terms in parabolic-elliptic chemotaxis-growth systems of the form \begin{align*} u_t &= Δu - \nabla\cdot(u\nabla v) + κ(x)u-μ(x)u^2, 0 &= Δv - v + u \end{align*} in smoothly bounded domains $Ω\subset\mathbb{R}^2$. Assuming that the coefficient functions satisfy $κ,μ\in C^0(\overlineΩ)$ with $μ\geq0$ we prove that finite-time blow-up of the classical solution can only occur in points where $μ$ is zero, i.e.\ that the blow-up set $\mathcal{B}$ is contained in \begin{align*} \big\{x\in\overlineΩ\midμ(x)=0\big\}. \end{align*} Moreover, we show that whenever $μ(x_0)>0$ for some $x_0\in\overlineΩ$, then one can find an open neighbourhood $U$ of $x_0$ in $\overlineΩ$ such that $u$ remains bounded in $U$ throughout evolution.
description: 15 pages
Quality Assurance for AI-based Systems: Overview and Challenges
Creators: name: Felderer, Michael
name: Ramler, Rudolf
Publisher: name: arXiv
Year: 2021
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: The number and importance of AI-based systems in all domains is growing. With the pervasive use and the dependence on AI-based systems, the quality of these systems becomes essential for their practical usage. However, quality assurance for AI-based systems is an emerging area that has not been well explored and requires collaboration between the SE and AI research communities. This paper discusses terminology and challenges on quality assurance for AI-based systems to set a baseline for that purpose. Therefore, we define basic concepts and characterize AI-based systems along the three dimensions of artifact type, process, and quality characteristics. Furthermore, we elaborate on the key challenges of (1) understandability and interpretability of AI models, (2) lack of specifications and defined requirements, (3) need for validation data and test input generation, (4) defining expected outcomes as test oracles, (5) accuracy and correctness measures, (6) non-functional properties of AI-based systems, (7) self-adaptive and self-learning characteristics, and (8) dynamic and frequently changing environments.
Quantum Logic with Interacting Bosons in 1D
Creators: name: Lahini, Yoav
name: Steinbrecher, Gregory R.
name: Bookatz, Adam D.
name: Englund, Dirk
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We present a scheme for implementing high-fidelity quantum logic gates using the quantum walk of a few interacting bosons on a one-dimensional lattice. The gate operation is carried out by a single compact lattice described by a one-dimensional Bose-Hubbard model with only nearest-neighbor hopping and on-site interactions. We find high-fidelity deterministic logic operations for a gate set (including the CNOT gate) that is universal for quantum information processing. We discuss the applicability of this scheme in light of recent developments in controlling and monitoring cold-atoms in optical lattices, as well as an implementation with realistic nonlinear quantum photonic devices.
description: 5 pages, 4 figures, comments welcome
Gravitational Waves of Type III Shapovalov Spacetimes: Particle Trajectories, Geodesic Deviation and Tidal Accelerations
Creators: name: Osetrin, Konstantin
name: Osetrin, Evgeny
name: Osetrina, Elena
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 83C10, 83C35

description: For gravitational-wave spacetimes of Shapovalov type III, exact general solutions of geodesic deviation equations and equations of motion of test particles are obtained. Solutions are found in a privileged coordinate system, where the metric of the considered spacetime models depends on the wave variable. The exact form of tidal accelerations of the gravitational wave is obtained. In the considered wave models of spacetime, the complete integral of the Hamilton-Jacobi equations of test particles can be constructed. An explicit form of the equations for the transition to a synchronous coordinate system is found, where the proper time of a test particle on the base geodesic is chosen as the time variable, and the time and space variables are separated. In the synchronous coordinate system, the form of the metric of the considered wave spacetime is presented, the form of the geodesic deviation vector and the tidal acceleration vector are obtained. The methods used in the paper and the results obtained are applicable to gravitational waves both in the general theory of relativity and in modified theories of gravity. The proposed approaches are applied to the case of Einstein's vacuum equations.
description: 27 pages
Assessing the Significance of Quantitative Trait Loci in Replicable Mapping Populations
Creators: name: Zou, F.
name: Xu, Z.
name: Vision, T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Replicable populations, such as panels of recombinant inbred or doubled haploid lines, are convenient resources for the mapping of QTL. To increase mapping power, replications are often collected within each RI line and a common way to analyze such data is to include in the QTL model only a single measurement from each line that represents the average among the replicates (a line means model). An obvious, but seldom explored, alternative, is to include every replicate in the model (a full data model). Here, we use simulations to compare these two approaches. Further, we propose an extension of the standard permutation procedure that is required to correctly control the type I error in mapping populations with nested structure.
Deleterious Epistatic Interactions Between Electron Transport System Protein-Coding Loci in the Copepod Tigriopus californicus
Creators: name: Willett, C. S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The nature of epistatic interactions between genes encoding interacting proteins in hybrid organisms can have important implications for the evolution of postzygotic reproductive isolation and speciation. At this point very little is known about the fitness differences caused by specific closely interacting but evolutionarily divergent proteins in hybrids between populations or species. The intertidal copepod Tigriopus californicus provides an excellent model in which to study such interactions because the species range includes numerous genetically divergent populations that are still capable of being crossed in the laboratory. Here, the effect on fitness due to the interactions of three complex III proteins of the electron transport system in F2 hybrid copepods resulting from crosses of a pair of divergent populations is examined. Significant deviations from Mendelian inheritance are observed for each of the three genes in F2 hybrid adults but not in nauplii (larvae). The two-way interactions between these genes also have a significant impact upon the viability of these hybrid copepods. Dominance appears to play an important role in mediating the interactions between these loci as deviations are caused by heterozygote/homozygote deleterious interactions. These results suggest that the fitness consequences of the interactions of these three complex III-associated genes could influence reproductive isolation in this system.
Infinitely dimensional Lax structure for one-dimensional Hubbard model
Creators: name: Popkov, Vladislav
name: Prosen, Tomaz
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: We report a two-parametric irreducible infinitely dimensional representation of the Lax integrability condition for the fermi Hubbard chain. Besides being of fundamental interest, hinting on possible novel quantum symmetry of the model, our construction allows for an explicit representation of an exact steady state many-body density operator for non-equilibrium boundary-driven Hubbard chain with arbitrary (asymmetric) particle source/sink rates at the letf/right end of the chain and with arbitrary boundary values of chemical potentials.
description: 5 pages in RevTex, 1 figure, version as accepted by Phys. Rev. Lett
การวิจัยและพัฒนาการจัดการเรียนการสอนโดยใช้แพลตฟอร์มออนไลน์และการบริหารจัดการหลักสูตรวิทยาศาสตรมหาบัณฑิต สาขาวิชาการจัดการอุตสาหกรรมและนวัตกรรม
Creators: name: ปิยมาภรณ์ ภูหนองโอง
Publisher: name: ศูนย์นวัตกรรมทางการศึกษา สื่อสิ่งพิมพ์ และสื่อออนไลน์ จุฬาลงกรณ์มหาวิทยาลัย
Year: 2565
Subjects: การบริหารจัดการเรียนการสอน
คุณภาพการจัดการเรียนการสอน
แพลตฟอร์มออนไลน์

description: วารสารครุศาสตร์, 50, 4, EDUCU5004007 (14 pages)
New Insights into Thermodynamics of Solutes in Neat and Complex Solvents
Creators: name: Przybyłek, Maciej
Publisher: name: figshare
Year: 2022
Subjects: subject: 30602 Chemical Thermodynamics and Energetics
subject: FOS: Chemical sciences
subject: Computational Chemistry
subject: 30502 Natural Products Chemistry
subject: 30504 Organic Green Chemistry
subject: 30699 Physical Chemistry not elsewhere classified
subject: 30505 Physical Organic Chemistry
subject: 30701 Quantum Chemistry
subject: 30605 Solution Chemistry
subject: 30206 Solid State Chemistry
subject: 30799 Theoretical and Computational Chemistry not elsewhere classified

description: Editorial: Special Issue “New Insights into Thermodynamics of Solutes in Neat and Complex Solvents”
 https://www.mdpi.com/journal/molecules/special_issues/thermodynamic_solvents
 Solubility is one of the most important physicochemical properties, both from a practical and theoretical perspective. Various fields benefit from the knowledge of this fundamental property, including pharmaceuticals, food technology, materials engineering and purification or separation techniques, including green extraction. Furthermore, solvent selection is important in sustainable technologies design, which was also addressed in the aims list of this Special Issue...
Internet Control and the Rise of Discrimination in India
Creators: name: Polcumpally, Arun Teja
name: Apoorva Ramachandra
Publisher: name: Zenodo
Year: 2023
Subjects: Misinformation
Digital technologies
Data regulation
Global policy

description: This paper aims to provide a comparative analysis of the policies drafted by the US, the EU, China, and India that would somehow regulate misinformation and mitigate the social impacts of the hyper-consumption of online information. The US, EU, and China are selected for the comparative analysis as they are considered the pioneers of data regulation and innovations in advanced digital technologies. In addition to the comparative analysis, this paper argues that in India, hate crimes when wedded to the uncontrolled spread of information across the internet require legislative, judicial, and educational interventions. This paper helps policymakers and academia find the best practices worldwide. Apart from identifying best practices, it also aids in formulating a tailored policy to control the misinformation in the internet channels of communication.
Covariant hamiltonian spin dynamics in curved space-time
Creators: name: d'Ambrosi, G.
name: Kumar, S. Satish
name: van Holten, J. W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The dynamics of spinning particles in curved space-time is discussed, emphasizing the hamiltonian formulation. Different choices of hamiltonians allow for the description of different gravitating systems. We give full results for the simplest case with minimal hamiltonian, constructing constants of motion including spin. The analysis is illustrated by the example of motion in Schwarzschild space-time. We also discuss a non-minimal extension of the hamiltonian giving rise to a gravitational equivalent of the Stern-Gerlach force. We show that this extension respects a large class of known constants of motion for the minimal case.
description: 14 pages, accepted version for Phys Lett B, added a footnote and two references
title: Machine learning approaches to complex time series
Creators: name: I. Stamp, D.
Publisher: name: University of Liverpool Repository
Year: 2023

description: It has been noted that there are numerous similarities between the behaviour of chaotic and stochastic systems. The theoretical links between chaotic and stochastic systems are investigated based on the evolution of the density of dynamics and an equivalency relationship based on the invariant measure of an ergodic system. It is shown that for simple chaotic systems an equivalent stochastic model can be analytically derived when the initial position in state space is only known to a limited precision. Based on this a new methodology for the modelling of complex nonlinear time series displaying chaotic behaviour with stochastic models is proposed. This consists of using a stochastic model to learn the evolution of the density of the dynamics of the chaotic system by estimating initial and transitional density functions directly from a time series. A number of models utilising this methodology are proposed, based on Markov chains and hidden Markov models. These are implemented and their performance and characteristics compared using computer simulation with several standard techniques.
Developmental Modulation of Nonhomologous End Joining in Caenorhabditis elegans
Creators: name: Clejan, I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Homologous recombination and nonhomologous end joining (NHEJ) are important DNA double-strand break repair pathways in many organisms. C. elegans strains harboring mutations in the cku-70, cku-80, or lig-4 NHEJ genes displayed multiple developmental abnormalities in response to radiation-induced DNA damage in noncycling somatic cells. These phenotypes did not result from S-phase, DNA damage, or mitotic checkpoints, apoptosis, or stress response pathways that regulate dauer formation. However, an additional defect in him-10, a kinetochore component, synergized with NHEJ mutations for the radiation-induced developmental phenotypes, suggesting that they may be triggered by mis-segregation of chromosome fragments. Although NHEJ was an important DNA repair pathway for noncycling somatic cells in C. elegans, homologous recombination was used to repair radiation-induced DNA damage in cycling somatic cells and in germ cells at all times. Noncycling germ cells that depended on homologous recombination underwent cell cycle arrest in G2, whereas noncycling somatic cells that depended on NHEJ arrested in G1, suggesting that cell cycle phase may modulate DNA repair during development. We conclude that error-prone NHEJ plays little or no role in DNA repair in C. elegans germ cells, possibly ensuring homology-based double-strand break repair and transmission of a stable genome from one generation to the next.
Holographic entanglement entropy in the nonconformal medium
Creators: name: Park, Chanyong
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate holographically the entanglement entropy of a nonconformal medium whose dual geometry is described by an Einstein-Maxwell-dilaton theory. Due to an additional conserved charge corresponding to the number operator, its thermodynamics can be represented in a grandcanonical or canonical ensemble. We study thermodynamics in both ensembles by using the holographic renormalization and the entanglement entropy of a nonconformal medium. After defining the entanglement chemical potential which unlike the entanglement temperature has a nontrivial size dependence, we find that the entanglement entropy of a small subsystem satisfies the relation resembling the first law of thermodynamics in a medium. Furthermore, we study the entanglement entropy change in the nonconformal medium caused by the excitation of the ground state and by the global quench corresponding to the insertion of particles.
description: 25 pages, no figure, more comments and references added
Drosophila ATR in Double-Strand Break Repair
Creators: name: LaRocque, J. R.
name: Sekelsky, J.
name: Jaklevic, B.
name: Su, T. T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The ability of a cell to sense and respond to DNA damage is essential for genome stability. An important aspect of the response is arrest of the cell cycle, presumably to allow time for repair. Ataxia telangiectasia mutated (ATM) and ATR are essential for such cell-cycle control, but some observations suggest that they also play a direct role in DNA repair. The Drosophila ortholog of ATR, MEI-41, mediates the DNA damage-dependent G2-M checkpoint. We examined the role of MEI-41 in repair of double-strand breaks (DSBs) induced by P-element excision. We found that mei-41 mutants are defective in completing the later steps of homologous recombination repair, but have no defects in end-joining repair. We hypothesized that these repair defects are the result of loss of checkpoint control. To test this, we genetically reduced mitotic cyclin levels and also examined repair in grp (DmChk1) and lok (DmChk2) mutants. Our results suggest that a significant component of the repair defects is due to loss of MEI-41-dependent cell cycle regulation. However, this does not account for all of the defects we observed. We propose a novel role for MEI-41 in DSB repair, independent of the Chk1/Chk2-mediated checkpoint response.
The Metadata4Ing Ontology. A basic introduction
Creators: name: Karmacharya, Ashish
name: Fuhrmans, Marc
Publisher: name: Zenodo
Year: 2022
Subjects: Forschungsdaten
Daten
Metadaten
Metadatenstandard
Metadatenmodell
Datenmodell
Forschungsdatenmanagement
FDM
Nachnutzung
Semantik
Semantischer Graph
FAIRe Daten
FAIR-Prinzipien
Standardisierung
Interoperabilität
Ontologie
Prozessorientierung
research data
data
metadata
metadata standard
metadata model
data model
research data management
RDM
reuse
semantics
semantic graph
FAIR data
FAIR principles
standardisation
interoperability
ontology
process orientation
m4i
Metadata4Ing
NFDI4Ing

description: Data documentation via metadata plays a major role in any research project and metadata is the key to finding and understanding even your own data. In addition, it provides a reliable record for future references and enables reuse and reproduction of results. In order to enable FAIR (findable, accessible, interoperable, reusable) use of research data, the documentation needs to follow standardized norms and be machine-actionable. For this, semantic models offer a wide range of benefits. Different metamodel schemas exist today, designed and developed for different purposes and disciplines. However, in many cases the vocabularies and their semantic definitions and formalizations do not fit actual engineering applications. Metadata4Ing (m4i) is an ontology based metamodel schema for process-based description of research, focusing on the provenance of both data and material objects. Metadata4Ing is intended as a general process model applicable to engineering and many other disciplines and focuses on general concepts like in- and output, employed methods and tools as well as the investigated entity, reusing terms of existing ontologies where possible.

 The HeFDI Research Data Days (HeFDI-Forschungsdatentage) allow researchers, lecturers and all other interested parties to get to know and try out different topics and offers in the field of research data management (RDM). In addition, various Hessian infrastructure facilities and centres present their offers and services.
description: The Research Data Days are an offer of the HeFDI Initiative (Landesinitiative HeFDI), which is funded by Hesse's Ministry for Science and Arts (HMWK).
A Hypothesis-Free Bridging of Disease Dynamics and Non-pharmaceutical Policies
Creators: Xiunan Wang
Hao Wang
Pouria Ramazi
Kyeongah Nah
Mark Lewis
Publisher: name: University of Alberta Library
Year: 2022

Accurate prediction of the number of daily or weekly confirmed cases of COVID-19 is critical to the control of the pandemic. Existing mechanistic models nicely capture the disease dynamics. However, to forecast the future, they require the transmission rate to be known, limiting their prediction power. Typically, a hypothesis is made on the form of the transmission rate with respect to time. Yet the real form is too complex to be mechanistically modeled due to the unknown dynamics of many influential factors. We tackle this problem by using a hypothesis-free machine-learning algorithm to estimate the transmission rate from data on non-pharmaceutical policies, and in turn forecast the confirmed cases using a mechanistic disease model. More specifically, we build a hybrid model consisting of a mechanistic ordinary differential equation (ODE) model and a gradient boosting model (GBM). To calibrate the parameters, we develop an “inverse method” that obtains the transmission rate inversely from the other variables in the ODE model and then feed it into the GBM to connect with the policy data. The resulting model forecasted the number of daily confirmed cases up to 35 days in the future in the USA with an averaged mean absolute percentage error of 27%. It can identify the most informative predictive variables, which can be helpful in designing improved forecasters as well as informing policymakers.
Hadronic models of blazars require a change of the accretion paradigm
Creators: name: Zdziarski, Andrzej A.
name: Boettcher, Markus
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We study hadronic models of broad-band emission of jets in radio-loud active galactic nuclei, and their implications for the accretion in those sources. We show that the models that account for broad-band spectra of blazars emitting in the GeV range in the sample of Boettcher et al. have highly super-Eddington jet powers. Furthermore, the ratio of the jet power to the radiative luminosity of the accretion disc is $\sim 3000$ on average and can be as high as $\sim 10^5$. We then show that the measurements of the radio core shift for the sample imply low magnetic fluxes threading the black hole, which rules out the Blandford-Znajek mechanism to produce powerful jets. These results require that the accretion rate necessary to power the modelled jets is extremely high, and the average radiative accretion efficiency is $\sim 4 \times 10^{-5}$. Thus, if the hadronic model is correct, the currently prevailing picture of accretion in AGNs needs to be significantly revised. Also, the obtained accretion mode cannot be dominant during the lifetimes of the sources, as the modelled very high accretion rates would result in too rapid growth of the central supermassive black holes. Finally, the extreme jet powers in the hadronic model are in conflict with the estimates of the jet power by other methods.
description: MNRAS, in press
ครุศึกษาเชิงพหุวัฒนธรรม
Creators: name: นันทน์ภัส แสงฮอง
Publisher: name: ศูนย์นวัตกรรมทางการศึกษา สื่อสิ่งพิมพ์ และสื่อออนไลน์ จุฬาลงกรณ์มหาวิทยาลัย
Year: 2565
Subjects: ครุศึกษาเชิงพหุวัฒนธรรม
การศึกษาพหุวัฒนธรรม
กระบวนทัศน์

description: วารสารครุศาสตร์, 50, 4, DUCU5004008 (13 pages)
title: Prospective observational cohort study of cutaneous leishmaniasis in Ethiopia - Informed consent form
Creators: name: Lambert, Saba
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2023

description: An observational, multi-centre cohort study to examine treatment outcomes for CL in Ethiopia which includes clinical outcomes, laboratory outcomes, patient reported outcome measures, scar assessments and cost effectiveness. These essential data will inform the design of randomized controlled trials to evaluate new treatment strategies, with appropriate economic evaluations. This will help improve evidence-based guidelines and support evidence-led policy decisions, not only in Ethiopia but also globally.
title: Strange fascination : a study of David Bowie
Creators: name: Kenneth Buckley, David
Publisher: name: University of Liverpool Repository
Year: 2023

description: This thesis examines the work of David Bowie and its main theme is identity construction. Bowie was the first male pop star to project a succession of personae and his vocal styles, stage performances, lyrical method and videos are analysed in the light of his redefinitions of himself for public consumption. Bowie's guiding aesthetic was that of collage and his indebtedness to a variety of extra-musical sources, most significantly from literature and the theatre, is discussed. The theses eschews traditional narrative approaches which have been used to discuss individuals within pop, and deals with its subject matter thematically. The thesis describes the context in which Bowie's work is set and discusses the commercial constraints on his art, the relationship between the work and pop ideology, and the struggle between his public and private selves. The interaction between iconography and fandom is shown as playing a crucial role in determining his importance, and this analysis draws on my findings from correspondence with Bowie fans. Bowie's protean art has demanded a multi-disciplinary analytical approach and the thesis discusses the usefulness of musicology, semiotics, subcultural theory and Postmodernist thinking. The thesis suggests a way of explaining individuals in pop through a theoretical equilibrium between text and context.
title: Post-Byzantine Church architecture in Cyprus, 1191-1571
Creators: name: Yioutani-Iacovides, Maria.
Publisher: name: University of Liverpool Repository
Year: 2023

description: Post-Byzantine Church Architecture in Cyprus during the period 1191-1571is crucial in the history of the island's architecture. It was influenced by two different traditions: the eastern Byzantine and the western medieval Gothic-Renaissance This architecture has been undervalued and only briefly discussed by scholars and historians, whereas the firescoes in the monuments have been thoroughly studied. This thesis seeks to establish how Post-I]yzantine Church Architecture developed under the influence of the historic circumstances of that time. it deals with Post-Byzantine architectural styles, lljcantine and Franco-Býwantine, the churches' typology, and the construction technology employed throughout the island. The research method has pursued two lines: extensive recording by visits to the churches and a review of the relevant literature. The intention of this research was to consider and study all the Post-Byzantine churches (around 301 churches) that were built or altered in the period 1191-1571, and which have retained their Original characteristics until the present day. Extensive visits were only possible to 206 of them; the others were studied through the literature, earlier photos, drawings, engravings and historical maps. An additional valuable source of information has been the fivsco-icons that illustrate models of the churches. The method of analysis was based on the classification of the churches according to their architectural style, types and their chronology. The thesis is divided into three parts (seven chapters). The first part tram historical information from the survey of the literature and analyses the author's observations after an assessment of the structural condition of the churches. The second, and main part describes the historical value of the churches and examines the development of the churches' architectural styles and types, their characteristics and architectural details. It also looks at construction materials, methods and techniques, and examines the geophysical characteristics of the island. ne third part sets out the conclusions.
Evidence for de Novo Evolution of Testis-Expressed Genes in the Drosophila yakuba/Drosophila erecta Clade
Creators: name: Begun, D. J.
name: Lindfors, H. A.
name: Kern, A. D.
name: Jones, C. D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The mutational origin and subsequent evolution of de novo genes, which are hypothesized to be genes of recent origin that are not obviously related to ancestral coding sequence, are poorly understood. However, accumulating evidence suggests that such genes may often function in male reproduction. Here we use testis-derived expressed sequence tags (ESTs) from Drosophila yakuba to identify genes that have likely arisen either in D. yakuba or in the D. yakuba/D. erecta ancestor. We found several such genes, which show testis-biased expression and are often X-linked. Comparative data indicate that three of these genes have very short open reading frames, which suggests the possibility that a significant number of testis-biased de novo genes in the D. yakuba/D. erecta clade may be noncoding RNA genes. These data, along with previously published data from D. melanogaster, support the idea that many de novo Drosophila genes function in male reproduction and that a small region of the X chromosome in the melanogaster subgroup may be a hotspot for the evolution of novel testis-biased genes.
On the smoothings of non-normal isolated surface singularities
Creators: name: Popescu-Pampu, Patrick
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics
subject: 14B07, 32S55

description: We show that isolated surface singularities which are non-normal may have Milnor fibers which are non-diffeomorphic to those of their normalizations. Therefore, non-normal isolated singularities enrich the collection of Stein fillings of links of normal isolated singularities. We conclude with a list of open questions related to this theme.
description: 14 pages, 1 figure. Compared to the first version on ArXiv, I added Remark 5.10, containing information communicated to me by J\'anos Koll\'ar. Proceedings of Singularities in Geometry and Applications III, Edinburgh, Scotland, 2013. J.-P. Brasselet, P. Giblin, V. Goryunov eds
title: Uranium isotope separation in the UK during World War II
Creators: name: Vincent. Attwood, Thomas
Publisher: name: University of Liverpool Repository
Year: 2023

description: This thesis investigates the practical, rather than theoretical, aspects of the uranium isotope separation technology developed in the United Kingdom during the Second World War. The overall scientific control of the bomb project was initially under G.P. Thomson but later devolved to Chadwick. Simon, at the University of Oxford, oversaw the practical aspects of isotope separation while Peierls, at Birmingham, was largely responsible for the theory, although many other leading scientists were involved in both the choice of a separation method and the associated measurement techniques required for its application. Frisch, the joint proposer of fission, was working on uranium isotope separation prior to the end of 1939. Frisch and Peierls produced a memorandum, in March 1940, which set the u.K. project in motion and eventually triggered the Americans into action. The Frisch-Peierls Memorandum led to the formation of the M.A.U.D. Committee which produced its report in July of 1941 that confirmed the scientific feasibility of such a weapon. A new and larger organisation, Tube Alloys, was then formed to complete the project. Virtually all methods of isotope separation were investigated before the choice of gas diffusion through a porous membrane was made. Most of the other methods became viable in the post war period or were applied to elements other than uranium. Two main problems had to be solved in the gas diffusion system: the design of a gas compressor system capable of operating at low absolute pressure, and the manufacture of a suitable diffusion membrane. A whole variety of membranes were investigated and a number taken to pilot production stage by small commercial firms. Experimental machines were designed and a pilot production plant constructed. The separation properties of both membranes and the diffusion machine were demonstrated. The transfer of core members of the team to America prevented completion of this work during the wartime period. The Americans, with their strong economy, wider range of scientific facilities, and enormous manufacturing capability, gradually assumed a leading role in the atomic work. The realisation that both the construction of both the separation plant and the manufacture of a bomb was beyond the financial and production capability of the U.K. led to the transfer of the leading members of the British team to America to pursue the project.
Improved $K_S$ tagging procedure and its impact on physics at KLOE-2
Creators: name: Silarski, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The KLOE experiment at the DA$Φ$NE $ϕ$-factory performed precise studies of charged and neutral kaon physics, low energy QCD, as well as tests of CP and CPT invariance. For the new run the KLOE has been upgraded by adding new tagger systems for the $γγ$ physics, the inner tracking chamber and two calorimeters in the final focusing region. We are also improving on kaon identification techniques, in particular algorithms for the $K_S$ meson tagging. In this article we discuss the impact of the improved tagging procedure on studies of the $K_S$ decays.
description: 5 pages, 2 figures
การวิเคราะห์องค์ประกอบเชิงยืนยันความพร้อมของเด็กที่กำลังขึ้นชั้นประถมศึกษาปีที่ 1
Creators: name: ยศวีร์ สายฟ้า
Publisher: name: ศูนย์นวัตกรรมทางการศึกษา สื่อสิ่งพิมพ์ และสื่อออนไลน์ จุฬาลงกรณ์มหาวิทยาลัย
Year: 2565
Subjects: รอยเชื่อมต่อทางการศึกษา
ความพร้อมสำหรับการมาโรงเรียน
การวิเคราะห์องค์ประกอบเชิงยืนยัน

description: วารสารครุศาสตร์, 50, 4, EDUCU5004009 (13 pages)
Flavour Dependent Gauged Radiative Neutrino Mass Model
Creators: name: Baek, Seungwon
name: Okada, Hiroshi
name: Yagyu, Kei
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose a one-loop induced radiative neutrino mass model with anomaly free flavour dependent gauge symmetry: $μ$ minus $τ$ symmetry $U(1)_{μ-τ}$. A neutrino mass matrix satisfying current experimental data can be obtained by introducing a weak isospin singlet scalar boson that breaks $U(1)_{μ-τ}$ symmetry, an inert doublet scalar field, and three right-handed neutrinos in addition to the fields in the standard model. We find that a characteristic structure appears in the neutrino mass matrix: two-zero texture form which predicts three non-zero neutrino masses and three non-zero CP-phases from five well measured experimental inputs of two squared mass differences and three mixing angles. Furthermore, it is clarified that only the inverted mass hierarchy is allowed in our model. In a favored parameter set from the neutrino sector, the discrepancy in the muon anomalous magnetic moment between the experimental data and the the standard model prediction can be explained by the additional neutral gauge boson loop contribution with mass of order 100 MeV and new gauge coupling of order $10^{-3}$.
description: 15 pages, 1 figure, 2 tables
High Frequency of Mutations That Expand the Host Range of an RNA Virus
Creators: name: Joyce, P.
name: Burch, C. L.
name: Ferris, M. T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The ability of a virus population to colonize a novel host is predicted to depend on the equilibrium frequency of potential colonists (i.e., genotypes capable of infecting the novel host) in the source population. In this study, we investigated the determinants of the equilibrium frequency of potential colonists in the RNA bacteriophage φ6. We isolated 40 spontaneous mutants capable of infecting a novel Pseudomonas syringae host and sequenced their host attachment genes to identify the responsible mutations. We observed 16 different mutations in the host attachment gene and used a new statistical approach to estimate that 39 additional mutations were missed by our screen. Phenotypic and fitness assays confirmed that the proximate mechanism underlying host range expansion was an increase in the ability to attach to the novel host and that acquisition of this ability most often imposed a cost for growth rate on two standard hosts. Considered in a population genetic framework, our data suggest that host range mutations should exist in phage populations at an equilibrium frequency (3 × 10−4) that exceeds the phage mutation rate by more than two orders of magnitude. Thus, colonization of novel hosts is unlikely to be limited by an inability to produce appropriate mutations.
Regularity of collections of sets and convergence of inexact alternating projections
Creators: name: Kruger, Alexander Y.
name: Thao, Nguyen H.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 49J53, 49K27, 58E30

description: We study the usage of regularity properties of collections of sets in convergence analysis of alternating projection methods for solving feasibility problems. Several equivalent characterizations of these properties are provided. Two settings of inexact alternating projections are considered and the corresponding convergence estimates are established and discussed.
Large-Scale Gene Expression Differences Across Brain Regions and Inbred Strains Correlate With a Behavioral Phenotype
Creators: name: Lauder, Jean
name: Threadgill, David W.
name: Magnuson, Terry R.
name: Zou, Fei
name: Moy, Sheryl S.
name: Crawley, Jacqueline N.
name: Wright, Fred A.
name: Huang, Hanwen
name: Nadler, Jessica J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Behaviors are often highly heritable, polygenic traits. To investigate molecular mediators of behavior, we analyzed gene expression patterns across seven brain regions (amygdala, basal ganglia, cerebellum, frontal cortex, hippocampus, cingulate cortex, and olfactory bulb) of 10 different inbred mouse strains (129S1/SvImJ, A/J, AKR/J, BALB/cByJ, BTBR T+ tf/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J, and FVB/NJ). Extensive variation was observed across both strain and brain region. These data provide potential transcriptional intermediates linking polygenic variation to differences in behavior. For example, mice from different strains had variable performance on the rotarod task, which correlated with the expression of >2000 transcripts in the cerebellum. Correlation with this task was also found in the amygdala and hippocampus, but not in other regions examined, indicating the potential complexity of motor coordination. Thus we can begin to identify expression profiles contributing to behavioral phenotypes through variation in gene expression.
Mutator Phenotype of Caenorhabditis elegans DNA Damage Checkpoint Mutants
Creators: name: Thomas, J. H.
name: Lowden, M.
name: Harris, J.
name: Ahmed, S.
name: Tzoneva, M.
name: Hodgkin, J.
name: Clejan, I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: DNA damage response proteins identify sites of DNA damage and signal to downstream effectors that orchestrate either apoptosis or arrest of the cell cycle and DNA repair. The C. elegans DNA damage response mutants mrt-2, hus-1, and clk-2(mn159) displayed 8- to 15-fold increases in the frequency of spontaneous mutation in their germlines. Many of these mutations were small- to medium-sized deletions, some of which had unusual sequences at their breakpoints such as purine-rich tracts or direct or inverted repeats. Although DNA-damage-induced apoptosis is abrogated in the mrt-2, hus-1, and clk-2 mutant backgrounds, lack of the apoptotic branch of the DNA damage response pathway in cep-1/p53, ced-3, and ced-4 mutants did not result in a Mutator phenotype. Thus, DNA damage checkpoint proteins suppress the frequency of mutation by ensuring that spontaneous DNA damage is accurately repaired in C. elegans germ cells. Although DNA damage response defects that predispose humans to cancer are known to result in large-scale chromosome aberrations, our results suggest that small- to medium-sized deletions may also play roles in the development of cancer.