cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Hogel-Free Holography
Creators: name: Heide, Felix
name: Chakravarthula, Praneeth
name: Tseng, Ethan
name: Fuchs, Henry
Publisher: name: Association for Computing Machinery (ACM)
Year: 2022

description: Holography is a promising avenue for high-quality displays without requiring bulky, complex optical systems. While recent work has demonstrated accurate hologram generation of 2D scenes, high-quality holographic projections of 3D scenes has been out of reach until now. Existing multiplane 3D holography approaches fail to model wavefronts in the presence of partial occlusion while holographic stereogram methods have to make a fundamental tradeoff between spatial and angular resolution. In addition, existing 3D holographic display methods rely on heuristic encoding of complex amplitude into phase-only pixels which results in holograms with severe artifacts. Fundamental limitations of the input representation, wavefront modeling, and optimization methods prohibit artifact-free 3D holographic projections in today's displays. To lift these limitations, we introduce hogel-free holography which optimizes for true 3D holograms, supporting both depth- and view-dependent effects for the first time. Our approach overcomes the fundamental spatio-angular resolution tradeoff typical to stereogram approaches. Moreover, it avoids heuristic encoding schemes to achieve high image fidelity over a 3D volume. We validate that the proposed method achieves 10Â dB PSNR improvement on simulated holographic reconstructions. We also validate our approach on an experimental prototype with accurate parallax and depth focus effects.
Expanding the Toolbox of Poly(2-Oxazoline)s-Based Hydrogels for Biomedical Applications
Creators: name: BIN ZAINAL OSMAN SHAH, MUHAMMAD SHAFFIQ
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 401609
subject: Polymers and plastics

description: Poly(2-oxazoline)s (POx) represent a class of polymers with immense promise in biomedical applications. The ability to easily incorporate side and main chain functionalities, achieved through the judicious selection of monomers and initiators/terminating agents, respectively, coupled with the biocompatibility and nature of their water-soluble counterparts, facilitates the development of highly functional POx materials. Diverse synthetic methodologies were employed to prepare POx-based hydrogels, intended to offer a comprehensive insight into the contemporary advancements in forming POx-based hydrogels. In addition, the flexibility in material properties and the equilibrium of hydrophilic/hydrophobic, create extensive opportunities for designing hydrogels based on POx for various biomedical applications.
Cratomorphus huautlaensis Zaragoza-Caballero 1996
Creators: name: Pérez-Hernández, Cisteil X.
name: Zaragoza-Caballero, Santiago
name: Romo-Galicia, Alberto
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Lampyridae
Cratomorphus
Cratomorphus huautlaensis

description: Cratomorphus huautlaensis Zaragoza-Caballero, 1996
MEXICO: MO Endemic
description: Published as part of Pérez-Hernández, Cisteil X., Zaragoza-Caballero, Santiago & Romo-Galicia, Alberto, 2022, Updated checklist of the fireflies (Coleoptera: Lampyridae) of Mexico, pp. 291-317 in Zootaxa 5092 (3) on page 299, DOI: 10.11646/zootaxa.5092.3.3, http://zenodo.org/record/5881269
Additional file 1: of Decoupled evolution of floral traits and climatic preferences in a clade of Neotropical Gesneriaceae
Creators: name: Serrano-Serrano, Martha
name: Perret, Mathieu
name: MaĂŻtĂŠ Guignard
name: Chautems, Alain
name: Silvestro, Daniele
name: Salamin, Nicolas
Publisher: name: Figshare
Year: 2015
Subjects: subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Plant Biology

description: Appendix S1. Phylogenetic analysis and relative divergence time estimation. Appendix S2. Visualization of continuous trait evolution. Table S1. List of species sampled, voucher information, Genbank accession numbers and binary trait information. Table S2. Pollinator, locality and source of information for Nematanthus species. Table S3. Mean values for floral traits. Table S4. Index Herbariorum acronyms and names. Table S5. PC loadings for morphological and climatic preferences. Table S6. AICc values for the complete set of OU models. Table S7. Model fit comparison correcting for measurement error (ME). Figure S1. Floral measurements. Figure S2. Phylogenetic reconstruction with outgroup species. Figure S3. Ancestral state reconstructions. Figure S4. Principal component analysis for floral traits (a) and climatic preferences (b). Figure S5. Comparison of phenotypic space and multi-rates BM model from raw and log-transformed measurements. Figure S6. Credibility tree from MrBayes with outgroup sequences included. (PDF 4115 kb)
Assessment of chemical exposure and self-reported health among tree planters in British Columbia
Creators: name: Gorman, Melanie Johanna
Publisher: name: University of British Columbia
Year: 2008

description: In British Columbia harvested forests are manually replanted by seasonal workers. Fertilizers contained in perforated paper sachets are often planted with seedlings. There have been anecdotal reports of skin and respiratory illness associated with fertilizer exposure and due to potential metal content in fertilizer source material they may contain metals as contaminants. Workers may also be exposed to pesticide residues on seedlings. This study aimed to characterize fertilizer, metal and pesticide exposure among a sample of B.C. tree planters, and to examine worker respiratory and dermal health. Between May 2006 and April 2007 223 tree planters were interviewed about their respiratory and dermal health, and the exposures of 54 tree planters at five geographically-disperse worksites were monitored. Four worksites were using fertilizer and one was not. The health questionnaire was a modification of the American Thoracic Society standardized questionnaire with questions on dermal health taken from a previous UBC study. Workers were grouped in exposure categories and symptoms analysed using logistic regression. Metals were measured by ICP/MS on post shift hand wipes, full shift air sample filters, in whole blood, bulk soil, seedling root balls, and fertilizer samples. Pesticides were measured on post shift hand wipes and on bulk seedling samples. Using nursery pesticide application records, analyses focused on known pesticides applied to the seedlings at the study sites. Carbamate pesticides were analyzed by HPLC/MS and other pesticides by GC/MS. No evidence was found that tree planters who work with fertilizer are at an elevated risk of exposure to arsenic, lead, cadmium, chromium and nickel relative to other tree planters. Pesticide residues were found on seedlings taken from coastal work sites in April 2007. At coastal worksites the fungicides chlorothalonil and iprodione were found on the skin of workers at low levels (range 0.37 – 106.3 ng.cm² and 0.48 – 15.9 ng/cm² respectively). Work with fertilizer was linked with an increased risk of cough, phlegm, nasal symptoms, nose bleed, and skin irritation. Hygiene conditions at tree planting work sites are very poor. Although measured exposures were low, hygiene conditions should improve to reduce the risk of health symptoms among tree planters.
Virtual, Augmented, and Mixed Reality for Human-robot Interaction: A Survey and Virtual Design Element Taxonomy
Creators: name: Phung, Thao
name: Walker, Michael
name: Williams, Tom
name: Szafir, Daniel
name: Chakraborti, Tathagata
Publisher: name: Association for Computing Machinery (ACM)
Year: 2023

description: Virtual, Augmented, and Mixed Reality for Human-Robot Interaction (VAM-HRI) has been gaining considerable attention in HRI research in recent years. However, the HRI community lacks a set of shared terminology and framework for characterizing aspects of mixed reality interfaces, presenting serious problems for future research. Therefore, it is important to have a common set of terms and concepts that can be used to precisely describe and organize the diverse array of work being done within the field. In this article, we present a novel taxonomic framework for different types of VAM-HRI interfaces, composed of four main categories of virtual design elements (VDEs). We present and justify our taxonomy and explain how its elements have been developed over the past 30 years as well as the current directions VAM-HRI is headed in the coming decade.
Medial prefrontal cortex neuropeptide Y modulates binge-like ethanol consumption in C57BL/6J mice
Creators: name: Robinson, Stacey L.
name: Reissner, Kathryn J.
name: Thiele, Todd E.
name: Marrero, Isabel M.
name: Perez-Heydrich, Carlos A.
name: Sepulveda-Orengo, Marian T.
Publisher: name: Springer Nature
Year: 2019

description: Neuropeptide Y (NPY) signaling via limbic NPY1 and 2 receptors (NPY1R and NPY2R, respectively) is known to modulate binge-like ethanol consumption in rodents. However, the role of NPY signaling in the medial prefrontal cortex (mPFC), which provides top-down modulation of the limbic system, is unknown. Here, we used “drinking-in-the-dark” (DID) procedures in C57BL/6J mice to address this gap in the literature. First, the impact of DID on NPY immunoreactivity (IR) was assessed in the mPFC. Next, the role of NPY1R and NPY2R signaling in the mPFC on ethanol consumption was evaluated through site-directed pharmacology. Chemogenetic inhibition of NPY1R+ neurons in the mPFC was performed to further evaluate the role of this population. To determine the potential role of NPY1R+ neurons projecting from the mPFC to the basolateral amygdala (BLA) this efferent population was selectively silenced. Three, 4-day cycles of DID reduced NPY IR in the mPFC. Intra-mPFC activation of NPY1R and antagonism of NPY2R resulted in decreased binge-like ethanol intake. Silencing of mPFC NPY1R+ neurons overall, and specifically NPY1R+ neurons projecting to the BLA, significantly reduced binge-like ethanol intake. We provide novel evidence that (1) bingelike ethanol intake reduces NPY levels in the mPFC; (2) activation of NPY1R or blockade of NPY2R reduces binge-like ethanol intake; and (3) chemogenetic inhibition of NPY1R+ neurons in the mPFC and NPY1R+ mPFC neurons projecting to the BLA blunts bingelike drinking.
XALQARO XUSUSIY HUQUQDA DELIKT MAJBURIYATLARNI HUQUQIY TARTIBGA SOLISH MUAMMOLARI
Creators: name: YUNUSOV NE'MATULLOXON XAMIDXON O'G'LI
Publisher: name: Zenodo
Year: 2024

description: Annotatsiya: Ushbu maqolada aynan xalqaro xususiy huquq tushunchasi hamda uni tizimlashtirish, ya'ni birlashtirish borasida dunyo tajribasi oʻrganilib, kamchiliklar va yutuqlari tahlil qilinadi. Shuningdek, bu borada olib borilayotgan ilmiy izlanishlar katta ahamiyatga ega ekanligi, individlar o'rtasida hududiy chegara bilmas munosabatlar vujudga kelishi, o'zgarishi va tugashini ham yaxlit huquqiy manba bilan tartibga solinishi ortiqcha vaqt va ziddiyatlarni oldini olishini inobatga olgan holda, xalqaro xususiy huquqni birlashtirishda muammolar yoritiladi. Bundan tashqari, maqolada muammolarni bartaraf qilish va bu jarayonni tartibga solish usullari bo'yicha takliflar haqida so’z boradi.

Kalit soʻzlar: xalqaro xususiy huquq, unifikatsiyalashgan qoidalar, integratsiyalashuv, yurisdiksiya.
Boletín # 51 - Flores, Tomates y Semillas - Más semillas y menos veneno para superar las crisis  del sistema de salud
Creators: name: Vaca González, Claudia Patricia
Publisher: name: Zenodo
Year: 2024

description: En el documento se menciona el contexto de la crisis actual del sistema de salud colombiano, también se hacen varias propuestas con el ánimo de avanzar en soluciones que permitan mejorar la experiencia de los usuarios que están teniendo dificultades en el acceso y se invita a un diálogo nacional.
Additional file 1: Figure S1. of Adipose-derived endothelial and mesenchymal stem cells enhance vascular network formation on three-dimensional constructs in vitro
Creators: name: Freiman, Alina
name: Shandalov, Yulia
name: Rozenfeld, Dekel
name: Shor, Erez
name: Segal, Sofia
name: Ben-David, Dror
name: Meretzki, Shai
name: Egozi, Dana
name: Levenberg, Shulamit
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Whole PLLA/PLGA scaffolds were cut perpendicularly to their horizontal plane into 5-micron sections. (DOCX 60 kb)
Cratomorphus limai Zaragoza-Caballero, Dominguez-Leon and Gonzalez-Ramirez 2021
Creators: name: Pérez-Hernández, Cisteil X.
name: Zaragoza-Caballero, Santiago
name: Romo-Galicia, Alberto
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Lampyridae
Cratomorphus
Cratomorphus limai

description: Cratomorphus limai Zaragoza-Caballero, Domínguez-León and González-Ramírez 2021
MEXICO: JC Endemic
description: Published as part of Pérez-Hernández, Cisteil X., Zaragoza-Caballero, Santiago & Romo-Galicia, Alberto, 2022, Updated checklist of the fireflies (Coleoptera: Lampyridae) of Mexico, pp. 291-317 in Zootaxa 5092 (3) on page 299, DOI: 10.11646/zootaxa.5092.3.3, http://zenodo.org/record/5881269
Additional file 2: Figure S2. of Adipose-derived endothelial and mesenchymal stem cells enhance vascular network formation on three-dimensional constructs in vitro
Creators: name: Freiman, Alina
name: Shandalov, Yulia
name: Rozenfeld, Dekel
name: Shor, Erez
name: Segal, Sofia
name: Ben-David, Dror
name: Meretzki, Shai
name: Egozi, Dana
name: Levenberg, Shulamit
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Developmental Biology
subject: Hematology
subject: Computational Biology

description: CD31 vs. vWF distribution in ECs of different origins. Paraffin-embedded sections (5 μm) of HAMECs:MSCs and HUVECs:HNDFs cultured for 7 days on PLLA/PLGA scaffolds, were stained for Ai DAPI (blue), Aii vWF (red) and Aiii CD31 (green) (scale bars = 50 μm). Aiv A merged image of the DAPI, vWF and CD31 staining is presented (Scale bar = 50 μm). Lumens are indicated with white arrows. (DOCX 209 kb)
Additional file 1: of Using digital technologies to engage with medical research: views of myotonic dystrophy patients in Japan
Creators: name: Coathup, Victoria
name: Teare, Harriet
name: Jusaku Minari
name: Yoshizawa, Go
name: Kaye, Jane
name: Takahashi, Masanori
name: Kato, Kazuto
Publisher: name: Figshare
Year: 2016
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Patient Survey in English. (PDF 92Â kb)
Cratomorphus picipennis Gorham 1881
Creators: name: Pérez-Hernández, Cisteil X.
name: Zaragoza-Caballero, Santiago
name: Romo-Galicia, Alberto
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Lampyridae
Cratomorphus
Cratomorphus picipennis

description: Cratomorphus picipennis Gorham, 1881
MEXICO: CS, VE; Guatemala
description: Published as part of Pérez-Hernández, Cisteil X., Zaragoza-Caballero, Santiago & Romo-Galicia, Alberto, 2022, Updated checklist of the fireflies (Coleoptera: Lampyridae) of Mexico, pp. 291-317 in Zootaxa 5092 (3) on page 299, DOI: 10.11646/zootaxa.5092.3.3, http://zenodo.org/record/5881269
Additional file 1: of A principal components method constrained by elementary flux modes: analysis of flux data sets
Creators: name: Stosch, Moritz Von
name: Azevedo, Cristiana Rodrigues De
name: Luis, Mauro
name: Sebastiao Feyo De Azevedo
name: Oliveira, Rui
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: Additional mathematical details of the algorithm, details for the generation of the simulation case data and additional results for the simulated Pichia pastoris and Saccharomyces cerevisiae case study (PDF 5250 kb)
Additional file 7: Figure S5. of Molecular phylogeny and dynamic evolution of disease resistance genes in the legume family
Creators: name: Fengya Zheng
name: Haiyang Wu
name: Rongzhi Zhang
name: Shiming Li
name: Weiming He
name: Fuk-Ling Wong
name: Genying Li
name: Shancen Zhao
name: Hon-Ming Lam
Publisher: name: Figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Chromosomal distributions of R-genes in the legume family. The different colors represent different species, and the Y-axis denotes the number of R-genes on each chromosome. Note that the legumes have different chromosomes and some genome assembly was not anchored to chromosomes. (PDF 591 kb)
Additional file 2: Figure S1. of Helminth infections and gut microbiota â   a feline perspective
Creators: name: Duarte, Ana
name: Jenkins, Timothy
name: Latrofa, Maria
name: Giannelli, Alessio
name: Papadopoulos, Elias
name: LuĂ­S De Carvalho
name: Nolan, Matthew
name: Otranto, Domenico
name: Cantacessi, Cinzia
Publisher: name: Figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Hierarchical clustering heatmap of the composition of the faecal microbiota phyla of Toxocara cati-positive (Tc+) and T. cati-negative (Tc-) cats. Dendrograms at the top of the heatmap indicate relationships between samples. Colour intensity represents the relative abundance of sequences representing the corresponding bacterial family in each sample. (PDF 63 kb)
Subcortical serotonin 5HT2c receptor-containing neurons sex-specifically regulate binge-like alcohol consumption, social, and arousal behaviors in mice
Creators: name: Hassanein, L.
name: Flanigan, M. E.
name: D'Ambrosio, S.
name: Kash, T. L.
name: Haun, H. L.
name: Boyt, K. M.
name: Hon, O. J.
name: Castle, M.
name: Pina, M. M.
Publisher: name: Springer Nature
Year: 2023

description: Binge alcohol consumption induces discrete social and arousal disturbances in human populations that promote increased drinking and accelerate the progression of Alcohol Use Disorder. Here, we show in a mouse model that binge alcohol consumption disrupts social recognition in females and potentiates sensorimotor arousal in males. These negative behavioral outcomes were associated with sex-specific adaptations in serotonergic signaling systems within the lateral habenula (LHb) and the bed nucleus of the stria terminalis (BNST), particularly those related to the receptor 5HT2c. While both BNST and LHb neurons expressing this receptor display potentiated activation following binge alcohol consumption, the primary causal mechanism underlying the effects of alcohol on social and arousal behaviors appears to be excessive activation of LHb5HT2c neurons. These findings may have valuable implications for the development of sex-specific treatments for mood and alcohol use disorders targeting the brain's serotonin system.
Additional file 9: Figure S7. of Molecular phylogeny and dynamic evolution of disease resistance genes in the legume family
Creators: name: Fengya Zheng
name: Haiyang Wu
name: Rongzhi Zhang
name: Shiming Li
name: Weiming He
name: Fuk-Ling Wong
name: Genying Li
name: Shancen Zhao
name: Hon-Ming Lam
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Percentage of R-genes (a) in clusters and (b) with singleton domains including NBS, LRR, TIR and CC. (PDF 436 kb)
Cratomorphus ramirezi Zaragoza-Caballero 1996
Creators: name: Pérez-Hernández, Cisteil X.
name: Zaragoza-Caballero, Santiago
name: Romo-Galicia, Alberto
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Lampyridae
Cratomorphus
Cratomorphus ramirezi

description: Cratomorphus ramirezi Zaragoza-Caballero, 1996
MEXICO: CS Endemic
description: Published as part of Pérez-Hernández, Cisteil X., Zaragoza-Caballero, Santiago & Romo-Galicia, Alberto, 2022, Updated checklist of the fireflies (Coleoptera: Lampyridae) of Mexico, pp. 291-317 in Zootaxa 5092 (3) on page 300, DOI: 10.11646/zootaxa.5092.3.3, http://zenodo.org/record/5881269
Distinct neurochemical influences on fMRI response polarity in the striatum
Creators: name: Wang, Tzu-Wen
name: Albaugh, Daniel L.
name: Katz, Brittany
name: Nonneman, Randal J.
name: Shih, Yen-Yu Ian
name: Stuber, Garret D.
name: Jiang, Jing
name: Cerri, Domenic H.
name: Chao, Tzu-Hao Harry
name: Hall, Catherine N.
name: Walton, Lindsay R.
name: Zhang, Weiting
name: Etkin, Amit
name: Lee, Sung-Ho
Publisher: name: Springer Nature
Year: 2024

description: The striatum, known as the input nucleus of the basal ganglia, is extensively studied for its diverse behavioral roles. However, the relationship between its neuronal and vascular activity, vital for interpreting functional magnetic resonance imaging (fMRI) signals, has not received comprehensive examination within the striatum. Here, we demonstrate that optogenetic stimulation of dorsal striatal neurons or their afferents from various cortical and subcortical regions induces negative striatal fMRI responses in rats, manifesting as vasoconstriction. These responses occur even with heightened striatal neuronal activity, confirmed by electrophysiology and fiber-photometry. In parallel, midbrain dopaminergic neuron optogenetic modulation, coupled with electrochemical measurements, establishes a link between striatal vasodilation and dopamine release. Intriguingly, in vivo intra-striatal pharmacological manipulations during optogenetic stimulation highlight a critical role of opioidergic signaling in generating striatal vasoconstriction. This observation is substantiated by detecting striatal vasoconstriction in brain slices after synthetic opioid application. In humans, manipulations aimed at increasing striatal neuronal activity likewise elicit negative striatal fMRI responses. Our results emphasize the necessity of considering vasoactive neurotransmission alongside neuronal activity when interpreting fMRI signal.
Limitations on tidal-in-stream power generation in a strait
Creators: name: Atwater, Joel
Publisher: name: University of British Columbia
Year: 2008

description: In the quest to reduce the release of carbon dioxide to limit the effects of global climate change, tidal-in-stream energy is being investigated as one of many possible sustainable means of generating electricity. In this scheme, turbines are placed in a tidal flow and kinetic energy is extracted. With the goal of producing maximum power, there is an ideal amount of resistance these turbines should provide; too little resistance will not a develop a sufficient pressure differential, while too much resistance will choke the flow. Tidal flow in a strait is driven by the difference in sea-level along the channel and is impeded by friction; the interplay between the driving and resistive forces determines the flow rate and thus the extractible power. The use of kinetic energy flux, previously employed as a metric for extractible power, is found to be unreliable as it does not account for the increased resistance the turbines provide in retarding the flow. The limits on extraction from a channel are dependant on the relationship between head loss and velocity. If head loss increases with the square of the velocity, a maximum of 38% of the total fluid power may be extracted; this maximum decreases to 25\% if head loss increases linearly with velocity. Using these values, the estimated power potential of BC's Inside Passage is 477MW, 13% of previous assessments. If a flow has the ability to divert through a parallel channel around the installed turbines, there are further limits on production. The magnitude of this diversion is a function of the relative resistance of impeded and diversion channels. As power extraction increases, the flow will slow from its natural rate. This reduction in velocity precipitously decreases the power density the flow, requiring additional turbine area per unit of power. As such, the infrastructure costs per watt may rise five to eight times as additional turbines are installed. This places significant economic limitations on utility-scale tidal energy production.
Additional file 1: Figure S1. of Histone methylation levels correlate with TGFBIp and extracellular matrix gene expression in normal and granular corneal dystrophy type 2 corneal fibroblasts
Creators: name: Maeng, Yong-Sun
name: Ga-Hyun Lee
name: Choi, Seung-Il
name: Kim, Kyu
name: Kim, Eung
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: Plant Biology

description: TGFBIp transcription was high in wild-type cells compared with that in GCD2 corneal fibroblasts and was related to H3K4me3 levels. (A) H3K4me3 levels at the Smad binding elements of TGFBIp gene promoters in wild-type, GCD2-heterozygous, and GCD2-homozygous corneal fibroblasts. ChIP assays were performed with H3K4me3 antibody. (mean ±SE). (B) mRNA levels of TGFBIp in corneal fibroblasts were determined by RT-qPCR. (C, D) Protein levels of TGFBIp in cell lysates or culture supernatants were determined by western blot. Figure S2. TGFb1 had a minor effect on H3K27me3 and H3K9me3 modification on the TGFBIp and ECM-associated gene promoters. Bar graphs showing H3K27me3 (A) and H3K9me3 (B) levels on the indicated gene promoters in control and TGFb1 (5 ng/ml)-stimulated corneal fibroblasts. ChIP assays were performed with H3K27me3 and H3K9me3 antibodies. (mean ±SE; **P < 0.01 vs. control, n = 3). Figure S3. SET7/9 knockdown attenuated the TGFb1-induced expression of TGFBIp and ECM-associated genes. Wild-type and GCD2-homozygous corneal fibroblasts were infected with SET7/9 or control shRNA lentivirus. After puromycin selection, SET7/9, H3K4me1, TGFBIp, and actin protein levels were analyzed by western blot (A) and infected cells were stimulated with TGFb1 (5 ng/ml) for 8 h, and mRNA and protein levels of TGFBIp were analyzed by RT-qPCR (B) and western blot (C). mRNA levels of ECM associated genes were analyzed by RT-qPCR (D). (mean ±standard error (SE); **P < 0.01 vs. control, n = 3). Figure S4. SET7/9 knockdown attenuated TGFb1-induced increases in H3K4me1 levels at the promoters of TGFBIp and ECM-associated genes. SET7/9 or control shRNA lentivirus infected cells were stimulated with TGFb1 (5 ng/ml) for 8 h, and H3K4me1 levels at the indicated gene promoters were analyzed. ChIP assays were performed with H3K4me1 antibody. (mean ± SE); **P < 0.01 vs. control, n = 3).
DELVE: feature selection for preserving biological trajectories in single-cell data
Creators: name: Beltran, Adriana S.
name: Redick, Margaret
name: Stallaert, Wayne
name: Ranek, Jolene S.
name: Stanley, Natalie
name: Wolff, Samuel C.
name: Purvis, Jeremy E.
name: Milner, J. Justin
Publisher: name: Springer Nature
Year: 2024

description: Single-cell technologies can measure the expression of thousands of molecular features in individual cells undergoing dynamic biological processes. While examining cells along a computationally-ordered pseudotime trajectory can reveal how changes in gene or protein expression impact cell fate, identifying such dynamic features is challenging due to the inherent noise in single-cell data. Here, we present DELVE, an unsupervised feature selection method for identifying a representative subset of molecular features which robustly recapitulate cellular trajectories. In contrast to previous work, DELVE uses a bottom-up approach to mitigate the effects of confounding sources of variation, and instead models cell states from dynamic gene or protein modules based on core regulatory complexes. Using simulations, single-cell RNA sequencing, and iterative immunofluorescence imaging data in the context of cell cycle and cellular differentiation, we demonstrate how DELVE selects features that better define cell-types and cell-type transitions. DELVE is available as an open-source python package: https://github.com/jranek/delve.
Use and performance of BioSand filters in Posoltega, Nicaragua
Creators: name: Vanderzwaag, Jason Corey
Publisher: name: University of British Columbia
Year: 2008

description: An evaluation of BioSand Filters, a method of Household Water Treatment, was conducted in Posoltega, Nicaragua, with objectives of determining the long-term filtration efficiency and the rate of sustained use. Field methods included microbial and turbidity water quality testing and interviews with filter users regarding the operation, maintenance and perceptions towards the filters. Of the 234 BioSand Filters installed in 1999 and 2004, only 24 were found to still be in operation. The average filtration efficiency was found to be 98% for total coliforms, 96% for E. coli and 88% for turbidity. Statistically significant effects on filtration efficiency were detected for the source contamination, the inverse of the flow rate, and the standing depth of water over the sand. A follow-up laboratory QA/QC procedure was undertaken to validate the field methods, which consisted of membrane filtration (MF) with m coliBlue24 growth media, and SolarCult dipslides. It was found that MF with m coliBlue24 produced useful reproducible results, and is an appropriate method for conducting field water quality testing. The dipslides were found to be an appropriate tool for testing source water quality and assessing the applicability of BioSand Filters, and may be an appropriate tool for local health representatives to promote safe water practices within the community. However, the dipslides should not be used as a presence / absence test for drinking water due to the high limit of detection. The low rate of sustained use (10%) is mostly a result of the structural failure of the concrete walls of the filter, in particular for those filters from 2004. Anecdotal evidence suggests insufficient quality control during the construction. The filtered water and the stored post-filtered water did not meet the WHO guidelines for safe drinking water on account of the presence of E. coli. Also identified were improper maintenance practices and unsafe storage of post-filtered water. These problems could have been addressed through the development of a holistic water system approach, such as the World Health Organization Water Safety Plan.
Rudolfina cavernicola Marshall & Fitzgerald 1997
Creators: name: Paiero, Steven Mark
name: Marshall, Stephen A.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Sphaeroceridae
Rudolfina
Rudolfina cavernicola

description: Rudolfina cavernicola Marshall & Fitzgerald, 1997
Fig. 21A
Material examined
The original type series from Kremmer’s Cave was re-examined along with the following material.
MEXICO • 1 ♂; San Luis Potosí, Cueva de Cinquenta y Ocho, 5 km S of San Francisco, 40 km E of San Luis Potosí, Municipio de Zaraqoza; 3000 m a.s.l.; 18 May 1972; Elliott, Ralph and Lynn leg.; DEBU.
Description
See Marshall and Fitzgerald 1997.
Distribution
Nearctic: United States of America (AZ, CO); Mexico (San Luis Potosí, newly recorded here).
Remarks
This species is newly recorded from Mexico. The illustration of this species that accompanied the original description (Marshall & Fitzgerald 1997: fig. 1) includes what appears to be a large seta coming off the anterior base of the surstylus; this is an unsocketed laminate lobe.
description: Published as part of Paiero, Steven Mark & Marshall, Stephen A., 2020, A revision of the genus Rudolfina Roháček (Sphaeroceridae: Limosininae), pp. 1-48 in European Journal of Taxonomy 593 on pages 16-18, DOI: 10.5852/ejt.2020.593, http://zenodo.org/record/3659777
Radula erigens M. A. M. Renner 2013, comb. et stat. nov.
Creators: name: Renner, Matt A. M.
name: Söderström, Lars
name: Hagborg, Anders
name: Konrat, Matt Von
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Plantae
Marchantiophyta
Jungermanniopsida
Porellales
Radulaceae
Radula
Radula erigens

description: Radula erigens (M.A.M.Renner et Braggins) M.A.M.Renner, comb. et stat. nov.
 Basionym:— Radula cordiloba subsp. erigens M.A.M.Renner et Braggins, J. Hattori Bot. Lab. 97: 45, 2005 (Renner 2005).
 Type: NEW ZEALAND. Kermadec Is.: Raoul Island, 1956 R . Cooper (holotype AK 44347 ex AKU063120!).
 Representative specimens examined:— NEW ZEALAND. Kermadec Is.: Raoul Island, Denham Bay Track, above Orange Cove, 29°14’556.9”S 177°55’54.1”W, 208 m, 18 May 2011, P.J. de Lange K742 (AK325678); Raoul Island, Moumoukai Track, 29°16’0”S 177°54’0”W, 384 m, 8 May 2009, P.J. de Lange K224 & D.C. Havell (AK313206); Raoul Island, Moumoukai Track, 29°16’0”S 177°54’0”W, 336 m, 15 May 2011, P.J. de Lange K741 (AK325676); Raoul Island, Denham Bay Track, 29°15’39.5”S 177°56’15.7”W, 271 m, 18 May 2011, P.J. de Lange K744 (AK325681); Raoul Island, 1956, R. C. Cooper 44350 (CHR558807).
 Notes:—To date known with certainty only from Raoul Island in the Kermadec Group, the northern most outlier of the New Zealand Botanical Region. On Raoul Island R. erigens grows in sheltered ravines, typically as a saxicol on exposed basalt on ravine walls, but also as an epiphyte on the bases of palm trunks. Radula erigens co-occurs with Lejeunea anisophylla Montagne (1843: 263), L. exilis (Reinwardt et al. 1824: 227) Grolle (1979: 353), L. gracilipes (Taylor 1846: 385) Spruce (1884: 213), Lopholejeunea sp. and Plagiochila pacifica Mitten (1873: 407), Papillaria crocea (Hampe 1853: 715) Jäger & Sauerbeck (1877: 267) and Echinodium umbrosum (Mitten 1859: 92) Jäger & Sauerbeck (1877: 314). Occurrence on islands elsewhere throughout the Pacific would not be unexpected, but to date examination of herbarium material and recent collecting activities in the Cook Islands (Rarotonga) and Fiji (Viti Levu, Kadavu, Taveuni) have failed to locate this species.
 Also examined:— Radula longispica Steph. INSULA WALLIS. Unea, 1902, Joly, herb Corbière 113. (Lectotype fide Yamada 1979, G-42698! [=G-15438!] 1); INSULA WALLIS. Unea, 1902, Joly (Isolectotype, FH!). The specimen identified as lectotype is cited as a holotype by So (2006). As no specific collection was indicated in the protologue, and there is more than one duplicate, it must be regarded as a lectotype instead.
description: Published as part of Renner, Matt A. M., Söderström, Lars, Hagborg, Anders & Konrat, Matt Von, 2013, Notes on Early Land Plants Today. 29. A new combination in Radula (Radulaceae, Marchantiophyta), pp. 12-14 in Phytotaxa 81 (1) on pages 12-13, DOI: 10.11646/phytotaxa.81.1.5, http://zenodo.org/record/5066991
Cratomorphus rodriguezae Zaragoza-Caballero 1996
Creators: name: Pérez-Hernández, Cisteil X.
name: Zaragoza-Caballero, Santiago
name: Romo-Galicia, Alberto
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Lampyridae
Cratomorphus
Cratomorphus rodriguezae

description: Cratomorphus rodriguezae Zaragoza-Caballero, 1996
MEXICO: CS, OA Endemic
description: Published as part of Pérez-Hernández, Cisteil X., Zaragoza-Caballero, Santiago & Romo-Galicia, Alberto, 2022, Updated checklist of the fireflies (Coleoptera: Lampyridae) of Mexico, pp. 291-317 in Zootaxa 5092 (3) on page 300, DOI: 10.11646/zootaxa.5092.3.3, http://zenodo.org/record/5881269
Additional file 3: Figure S3. of
                     Drosophila innate immunity: regional and functional specialization of prophenoloxidases
Creators: name: Dudzic, Jan
name: Kondo, Shu
name: Ueda, Ryu
name: Bergman, Casey
name: Lemaitre, Bruno
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology
subject: Computational Biology

description: Phylogenetic tree of PPO genes from Drosophila species. A maximum likelihood phylogenetic tree was constructed with the exonic sequences of PPO1, PPO2 and PPO3 using RAxML. Nodes with more than 90Â % bootstrap support are labeled. Branch lengths are in substitutions per site. The tree is midpoint rooted and based on a multiple alignment of all PPO genes from D. melanogaster, D. simulans, D. sechellia, D. yakuba, D. erecta, D. eugracilis, D. suzukii, D. biarmipes, D. takahashii, D. rhopaloa, D. elegans, D. ficusphila, D. kikkawai, D. bipectinata, D. ananassae, D. pseudoobscura, D. persimilis, D. miranda, D. willistoni, D. mojavensis, D. virilis, D. albomicans and D. grimshawi. The placement of the root in our tree is supported by a previous phylogenetic analysis of PPO genes across arthropods [8] (PDF 182 kb)
Enzyme Release from Polyion Complex by Extremely Low Frequency Magnetic Field
Creators: name: Vishwasrao, Hemant
name: Golovin, Yuri I.
name: Klyachko, Natalia L.
name: Abakumov, Maxim A.
name: Poloznikov, Andrey Ð.
name: Kabanov, Alexander V.
name: Majouga, Alexander G.
name: Vlasova, Kseniya Yu.
name: Gribanovsky, Sergey L.
name: Zhigachev, Alexander O.
name: Golovin, Dmitry Yu.
name: Sokolsky-Papkov, Marina
Publisher: name: Springer Nature
Year: 2020

description: Remote nano-magneto-mechanical actuation of magnetic nanoparticles (MNPs) by non-heating extremely low frequency magnetic field (ELF MF) is explored as a tool for non-invasive modification of bionanomaterials in pharmaceutical and medical applications. Here we study the effects of ELF MF (30–160 Hz, 8–120 kA/m) on the activity and release of a model enzyme, superoxide dismutase 1 (SOD1) immobilized by polyion coupling on dispersed MNPs aggregates coated with poly(L-lysine)-blockpoly(ethylene glycol) block copolymer (s-MNPs). Such fields do not cause any considerable heating of MNPs but promote their rotating-oscillating mechanical motion that produces mechanical forces and deformations in adjacent materials. We observed the changes in the catalytic activity of immobilized SOD1 as well as its release from the s-MNPs/SOD1 polyion complex upon application of the ELF MF for 5 to 15 min. At longer exposures (25 min) the s-MNPs/SOD1 dispersion destabilizes. The bell-shaped effect of the field frequency with maximum at f = 50 Hz and saturation effect of field strength (between 30 kA/m and 120 kA/m at f = 50 Hz) are reported and explained. The findings are significant as one early indication of the nano-magneto-mechanical disruption by ELF MF of cooperative polyion complexes that are widely used for design of current functional healthcare bionanomaterials.
Additional file 6: Figure S4. of Molecular phylogeny and dynamic evolution of disease resistance genes in the legume family
Creators: name: Fengya Zheng
name: Haiyang Wu
name: Rongzhi Zhang
name: Shiming Li
name: Weiming He
name: Fuk-Ling Wong
name: Genying Li
name: Shancen Zhao
name: Hon-Ming Lam
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: Boxplot showing the lengths of R proteins identified in legumes. The length of an R protein was expressed in number of amino acid residues (aa). (PDF 141 kb)
Disturbance intensification is altering the trait composition of Caribbean reefs, locking them into a low functioning state
Creators: name: Mudge, Laura
name: Bruno, John F.
Publisher: name: Springer Nature
Year: 2023

description: Anthropogenic climate change is intensifying natural disturbance regimes, which negatively affects some species, while benefiting others. This could alter the trait composition of ecological communities and influence resilience to disturbance. We investigated how the frequency and intensification of the regional storm regime (and likely other disturbances) is altering coral species composition and in turn resistance and recovery. We developed regional databases of coral cover and composition (3144 reef locations from 1970 to 2017) and of the path and strength of cyclonic storms in the region (including 10,058 unique storm-reef intersections). We found that total living coral cover declined steadily through 2017 (the median annual loss rate wasâ€‰~â€‰0.25% per year). Our results also indicate that despite the observed increase in the intensity of Atlantic cyclonic storms, their effect on coral cover has decreased markedly. This could be due in part to selection for disturbance-resistant taxa in response to the intensifying disturbance regime. We found that storms accelerated the loss of threatened acroporid corals but had no measurable effect on the cover of more resilient â€œweedyâ€ corals, thereby increasing their relative cover. Although resistance to disturbance has increased, recovery rates have slowed due to the dominance of small, slow-growing species. This feedback loop is locking coral communities into a low-functioning state dominated by weedy species with limited ecological or societal value.
Hypothalamic Supramammillary Control of Cognition and Motivation.
Creators: name: Thirtamara Rajamani, Keerthi
name: Kesner, Andrew J
name: Arima, Yosuke
name: Mozaffarilegha, Marjan
name: Song, Juan
name: Hashimotodani, Yuki
name: Ikemoto, Satoshi
name: Ito, Hiroshi T
name: Harony-Nicolas, Hala
Publisher: name: Society for Neuroscience
Year: 2023

description: The supramammillary nucleus (SuM) is a small region in the ventromedial posterior hypothalamus. The SuM has been relatively understudied with much of the prior focus being on its connection with septo-hippocampal circuitry. Thus, most studies conducted until the 21st century examined its role in hippocampal processes, such as theta rhythm and learning/memory. In recent years, the SuM has been "rediscovered" as a crucial hub for several behavioral and cognitive processes, including reward-seeking, exploration, and social memory. Additionally, it has been shown to play significant roles in hippocampal plasticity and adult neurogenesis. This review highlights findings from recent studies using cutting-edge systems neuroscience tools that have shed light on these fascinating roles for the SuM.
A Computational Design Pipeline to Fabricate Sensing Network Physicalizations
Creators: name: Rivera, Michael L.
name: Ynnerman, Anders
name: Fujiwara, Takanori
name: Bae, S. Sandra
name: Szafir, Danielle Albers
name: Yi-Luen, Ellen
Publisher: name: Institute of Electrical and Electronics Engineers (IEEE)
Year: 2023

description: Interaction is critical for data analysis and sensemaking. However, designing interactive physicalizations is challenging as it requires cross-disciplinary knowledge in visualization, fabrication, and electronics. Interactive physicalizations are typically produced in an unstructured manner, resulting in unique solutions for a specific dataset, problem, or interaction that cannot be easily extended or adapted to new scenarios or future physicalizations. To mitigate these challenges, we introduce a computational design pipeline to 3D print network physicalizations with integrated sensing capabilities. Networks are ubiquitous, yet their complex geometry also requires significant engineering considerations to provide intuitive, effective interactions for exploration. Using our pipeline, designers can readily produce network physicalizations supporting selection-the most critical atomic operation for interaction-by touch through capacitive sensing and computational inference. Our computational design pipeline introduces a new design paradigm by concurrently considering the form and interactivity of a physicalization into one cohesive fabrication workflow. We evaluate our approach using (i) computational evaluations, (ii) three usage scenarios focusing on general visualization tasks, and (iii) expert interviews. The design paradigm introduced by our pipeline can lower barriers to physicalization research, creation, and adoption.
Cratomorphus signativentris Olivier 1895
Creators: name: Pérez-Hernández, Cisteil X.
name: Zaragoza-Caballero, Santiago
name: Romo-Galicia, Alberto
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Lampyridae
Cratomorphus
Cratomorphus signativentris

description: Cratomorphus signativentris Olivier, 1895
MEXICO: CS, OA, QR, SL, TB, VE; Colombia; Nicaragua; Panama; Venezuela
description: Published as part of Pérez-Hernández, Cisteil X., Zaragoza-Caballero, Santiago & Romo-Galicia, Alberto, 2022, Updated checklist of the fireflies (Coleoptera: Lampyridae) of Mexico, pp. 291-317 in Zootaxa 5092 (3) on page 300, DOI: 10.11646/zootaxa.5092.3.3, http://zenodo.org/record/5881269
Additional file 4: Figure S4. of
                     Drosophila innate immunity: regional and functional specialization of prophenoloxidases
Creators: name: Dudzic, Jan
name: Kondo, Shu
name: Ueda, Ryu
name: Bergman, Casey
name: Lemaitre, Bruno
Publisher: name: Figshare
Year: 2015
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Survival analysis after Leptopilina clavipes and L. boulardi wasp infestation in wild type and PPO mutants. Synchronized L2 larvae were exposed to gravid female L. clavipes (A) or L. boulardi (B) wasps in custom infection traps, re-isolated and cultured at room temperature until wasps emerged. Vials were scored daily for total number numbers of eclosed flies and wasps. PPO3 mutant larvae show enhanced susceptibility against L. clavipes, whereas the loss of all PPO does not further increase this effect. The mild effect of PPO mutants on wasp encapsulation led us to hypothesize that optimal encapsulation requires a precise level of phenoloxidase activity due to a possible toxic effect on the host (PDF 41 kb)