cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 7 of Effects of stressful life-events on DNA methylation in panic disorder and major depressive disorder
Creators: name: Czamara, Darina
name: Neufang, Alexa
name: Dieterle, Roman
name: Iurato, Stella
name: Arloth, Janine
name: Martins, Jade
name: Ising, Marcus
name: Binder, Elisabeth E.
name: Erhardt, Angelika
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 7: Figure S7. Manhattan plot for meta-analysis of EWAS of wposLE in PDI cases and PDII cases. Chromosomal position is depicted on the x-axis, −log10(p-value) on the y-axis. The blue line indicates nominal p-values
Additional file 8 of Effects of stressful life-events on DNA methylation in panic disorder and major depressive disorder
Creators: name: Czamara, Darina
name: Neufang, Alexa
name: Dieterle, Roman
name: Iurato, Stella
name: Arloth, Janine
name: Martins, Jade
name: Ising, Marcus
name: Binder, Elisabeth E.
name: Erhardt, Angelika
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 8: Figure S8. Manhattan plot for EWAS of wnegLE in PDI cases. Chromosomal position is depicted on the x-axis, −log10(p-value) on the y-axis. The blue line indicates nominal p-values
Additional file 9 of Effects of stressful life-events on DNA methylation in panic disorder and major depressive disorder
Creators: name: Czamara, Darina
name: Neufang, Alexa
name: Dieterle, Roman
name: Iurato, Stella
name: Arloth, Janine
name: Martins, Jade
name: Ising, Marcus
name: Binder, Elisabeth E.
name: Erhardt, Angelika
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 9: Figure S9. Manhattan plot for EWAS of wnegLE in PDII cases. Chromosomal position is depicted on the x-axis, −log10(p-value) on the y-axis. The blue line indicates nominal p-values
Natural anti-A and Tn-cross-reactive IgM arise from developmental O-GalNAc glycosylations.*
Creators: name: Arend, Peter
Publisher: name: figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Hematology
subject: Medicine
subject: Biochemistry
subject: Developmental Biology
subject: Zoology
subject: 60114 Systems Biology
subject: Structural Biology
subject: Stem Cells
subject: Cell Biology
subject: Genetics

description: While eukaryotic O-GalNAc-Ser/Thr glycosylations do not occur in bacteria, the O-GalNAc glycan-bearing ovarian glycolipids, discovered in C57BL/10 mice, are complementary to the syngeneic, anti-A-reactive immunoglobulin M (IgM), which does not appear in animals that have undergone ovariectomy prior to the onset of puberty. These mammalian ovarian glycolipids are also complementary to the anti-A/Tn cross-reactive Helix pomatia agglutinin, an eukaryotic defense protein, which has emerged from the egg coats of the snail and reveals its functional O-GalNAc glycan. The hexameric structure of this primitive, eukaryotic defense protein suggests an evolutionary relationship to the mammalian non-immune IgM molecule, which hypothetically obtains its complementarity from the early trans-species O-GalNAc glycosylation of proteins and subsequent GalNAc transferase depletion that completes the cell differentiation processes and causes the release of O-glycan-depleted, complementary proteins, such as secretory IgM revealing the structure of the volatilely expressed, “lost” glycan carrier through germline-specific serine residues. Consequently, the early or first O-GalNAc glycosylations of proteins appear metabolically related to those of the mucin-type, “aberrant” monosaccharide GalNAcα1-O-Ser/Thr-R, also referred to as the Tn antigen, and explain the anti-Tn cross-reactivity of anti-A-specific immunoglobulins and the pronounced occurrence of cross-reactive anti-Tn antibody in plasma from humans with histo (blood) group O. In fact, in human blood group O, A-allelic, phenotype-specific GalNAc glycosylation of plasma proteins does not occur, affecting the levels of the anti-Tn antibody, which may function as a growth regulator that, depending on its levels, initiates a complex process of growth inhibition through enzyme-substrate competition with subsequent trans-species O-GalNAc-glycosylations.
The Perceived Performance of Spatial Audio for Teleconferencing
Creators: name: Evans, Michael
Publisher: name: figshare
Year: 2014
Subjects: Applied Computer Science

description: (DPhil Thesis, University of York, 1997) Modern teleconference applications and services attempt to make communication between participants at remote sites more effective by presenting information in a manner which is perceived as much like natural, physical interaction as possible. Spatial audio - reproducing sound so that it is perceived as emanating from meaningful positions in space - is a technology which has the potential to increase this perceptual realism, or Telepresence. Spatialised sound can be created by using an array of loudspeakers to simulate a remote or virtual sound field across a listening space, or by ensuring that appropriate sound localisation cues are present in the signals detected at the ears. However, in telecommunications the unambiguous, comfortable and accurate transmission of speech is of primary importance. Therefore, it is critical that any additional perceptual realism afforded by the integration of spatial audio into teleconferencing systems does not compromise the perceived performance of the systems in terms of participants’ understanding of the words being conveyed. This thesis uses formal subjective testing methods to verify that the spatial reproduction of speech does not compromise perceived performance relative to non-spatialised reproduction. Indeed, under teleconference conditions, where the primary speech stimulus may be occluded by additional voices or by peripheral noise or vocal babble, spatialisation has been found to yield significant improvements in the performance as perceived by listeners. Such improvements are demonstrated for speech spatialised using ambisonic techniques, and also for spatial audio created using a novel perceptual synthesis technique based on a new continuous functional analysis of directional hearing measurements using surface spherical harmonics. The thesis consists of a comprehensive introduction to teleconferencing and the complementary issues of sound localisation and spatialisation together with a description of the physical measurements, mathematical modelling and subjective testing carried out in this research. Conclusions and suggestions for future work are also made.
Additional file 1 of Comparative analysis of Thalassionema chloroplast genomes revealed hidden biodiversity
Creators: name: Zhang, Mengjia
name: Chen, Nansheng
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Ecology

description: Additional file 1. Table S1. Amount of clean reads of seven samples used for analysis.
Additional file 1 of Cooking outdoors or with cleaner fuels does not increase malarial risk in children under 5 years: a cross-sectional study of 17 sub-Saharan African countries
Creators: name: Woolley, Katherine E.
name: Bartington, Suzanne E.
name: Pope, Francis D.
name: Greenfield, Sheila M.
name: Tusting, Lucy S.
name: Price, Malcolm J.
name: Thomas, G. Neil
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Table S1.1. Predictors included with the PCA analysis for the modified wealth index by country.
title: Sepsis in tropical Australia
title: epidemiology, pathophysiology and adjunctive therapy
titleType: Subtitle
Creators: name: Davis, Joshua
Publisher: name: Charles Darwin University
Year: 2010

description: Despite substantial advances in its management, severe sepsis remains the most common cause of death in intensive care units, and has a mortality of 30-50%. Within Australia, there are an estimated 15,000 cases of severe sepsis each year. However the epidemiology of sepsis in the tropical Northern Territory, a region with a high incidence of acute infections and chronic diseases, and a high proportion of Indigenous residents, has not been described. The pathophysiology of sepsis is complex and incompletely understood. A pivotal factor in sepsis pathophysiology is dysfunction of the endothelium, a metabolically active organ which lines the entire vascular system. Following the literature reviews in section A, this thesis is divided into three parts. In section B, I present a 12-month prospective cohort study based at Royal Darwin Hospital describing the epidemiology of sepsis in the Top End of the Northern Territory. This study found that the incidence of sepsis in this region is five-fold higher than that in temperate Australia and elsewhere, and that most of this burden occurs in Indigenous people. In section C, I undertook an observational study examining endothelial function in patients with sepsis and healthy controls, using a novel technique called peripheral arterial tonometry. This study found that peripheral arterial tonometry is a feasible technique for monitoring endothelial function in sepsis and that endothelial function is impaired in proportion to disease severity. It also identified several potential targets for development of therapeutic intervention to improve the endothelial and microvascular dysfunction of sepsis. One of the most promising potential adjunctive therapies for sepsis is the statins, a class of lipid-lowering drugs. Section D describes the rationale and protocol for a currently recruiting randomised trial of atorvastatin to improve endothelial function in patients with severe sepsis.
title: Journée MASA- Partager les archives et les données archéologiques, MASA au service de la communauté
Publisher: name: MSH Val de Loire
Year: 2021

description: Les 21 et 22 septembre 2021, le consortium MASA a organisé une rencontre nationale réunissant la communauté archéologique française dans toutes ses dimensions (ministère de la Culture, Conseil national de   la recherche archéologique, archéologie préventive publique — Inrap et   collectivités territoriales — et privée, archéologie française à   l’étranger — Réseau des Écoles françaises à l’étranger et Unités mixtes   des Instituts français de recherche à l’étranger – UMIFRE —,   universités, CNRS et sociétés savantes). Cette rencontre a permis de   présenter l’écosystème numérique et la palette d’outils qui le compose, ainsi qu’une offre de formation   aux bonnes pratiques à travers les principaux outils.  L’objectif de   cette rencontre est de diffuser largement les pratiques et les outils   pour la mise à disposition de corpus archéolog
Additional file 2 of Cooking outdoors or with cleaner fuels does not increase malarial risk in children under 5 years: a cross-sectional study of 17 sub-Saharan African countries
Creators: name: Woolley, Katherine E.
name: Bartington, Suzanne E.
name: Pope, Francis D.
name: Greenfield, Sheila M.
name: Tusting, Lucy S.
name: Price, Malcolm J.
name: Thomas, G. Neil
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2: Table S2.1. Unadjusted and adjusted odds ratio of malarial infection with solid biomass fuels and kerosene cooking compared to cleaner cooking—Analysis 1. Table S2.2. Unadjusted and adjusted odds ratio of malarial infection with wood cooking compared to charcoal cooking—Analysis 2. Table S2.3. Unadjusted and adjusted odds ratio of malarial infection with cooking location (outdoor, in a separate building) compared to indoors—Analysis 3.
Natural anti-A and Tn-cross-reactive IgM arise from developmental O-GalNAc glycosylations.*
Creators: name: Arend, Peter
Publisher: name: figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Hematology
subject: Medicine
subject: Biochemistry
subject: Developmental Biology
subject: Zoology
subject: 60114 Systems Biology
subject: Structural Biology
subject: Stem Cells
subject: Cell Biology
subject: Genetics

description: When the O-GalNAc glycan-bearing ovarian glycolipids, discovered in the C57BL/10 mouse, are complementary to its syngeneic, anti-A-reactive immunoglobulin M (IgM), which does not appear in animals that have undergone ovariectomy prior to the onset of puberty, these mammalian ovarian glycolipids are also complementary to the anti-A/Tn cross-reactive Helix pomatia agglutinin, an eukaryotic defense protein, which has emerged from the egg coats of the snail and reveals its recently discovered O-GalNAc glycan. The hexameric structure of this primitive, invertebrate defense protein suggests an evolutionary relationship to the mammalian non-immune defense protein or ancestral IgM molecule, which hypothetically obtains its complementarity from the early trans-species O-GalNAc glycosylation of proteins and subsequent GalNAc transferase depletion that completes the cell differentiation processes and causes the release of O-glycan-depleted, complementary proteins, such as secretory IgM revealing the structure of the volatilely expressed, “lost” glycan carrier through germline-specific serine residues. Consequently, the early or first O-GalNAc glycosylations of proteins appear metabolically related to those of the mucin-type, “aberrant” monosaccharide GalNAcα1-O-Ser/Thr-R, also referred to as the Tn antigen, and explain the anti-Tn cross-reactivity of anti-A-specific immunoglobulins and the pronounced occurrence of cross-reactive anti-Tn antibody in plasma from humans with histo (blood) group O. In fact, in human blood group O, A-allelic, phenotype-specific GalNAc glycosylation of plasma proteins does not occur, affecting the levels of the anti-Tn antibody, which may function as a growth regulator that, depending on its levels, initiates a complex process of growth inhibition through enzyme-substrate competition with subsequent trans-species O-GalNAc-glycosylations.
Additional file 3 of Cooking outdoors or with cleaner fuels does not increase malarial risk in children under 5 years: a cross-sectional study of 17 sub-Saharan African countries
Creators: name: Woolley, Katherine E.
name: Bartington, Suzanne E.
name: Pope, Francis D.
name: Greenfield, Sheila M.
name: Tusting, Lucy S.
name: Price, Malcolm J.
name: Thomas, G. Neil
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 3: Table S3.1. Unadjusted odds ratio of malarial infection for each cooking practices for the combined dataset, exploratory and sub-analysis.
Additional file 1 of Incipient speciation between host-plant strains in the fall armyworm
Creators: name: Durand, Karine
name: Yainna, Sudeeptha
name: Nam, Kiwoong
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. The result of principal component analysis with the information of sampled locations. Figure S2. The principal component analysis shown in Fig. 2 in the main text with+geom_point(position=position_jitter(h=0.1, w=0.1)) function to reduce overlapping among points for visualization purpose. Here, random numbers ranging between 0 and 0.1 were added to both the x-axis and y-axis to each point to spread the points.
CESSDA SaW D2.1: Knowledge-Sharing Platform Forum Report
Creators: name: Alfredsson, Iris
name: Jerlehag, Birger
name: Vipavc Brvar, Irena
name: Besjak, Sonja
name: Smith, Eleanor
name: Recker, Jonas
Publisher: name: Zenodo
Year: 2016
Subjects: Strategy and Policy

description: This report presents results of Task 2.1 "Virtual Stakeholders' Forum" – an online survey carried out among CESSDA SaW members to learn more about their needs and demands concerning the CESSDA Knowledge Platform to be built as part of this task. The survey, which was completed by 47 respondents, focused on desired content and functionality of the platform. Its results inform the Platform Content and Management Policy (D2.2)
Natural anti-A and Tn-cross-reactive IgM arise from developmental O-GalNAc glycosylations.*
Creators: name: Arend, Peter
Publisher: name: figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Hematology
subject: Medicine
subject: Biochemistry
subject: Developmental Biology
subject: Zoology
subject: 60114 Systems Biology
subject: Structural Biology
subject: Stem Cells
subject: Cell Biology
subject: Genetics

description: When the O-GalNAc glycan-bearing ovarian glycolipids, discovered in the C57BL/10 mouse, are complementary to its syngeneic, anti-A-reactive immunoglobulin M (IgM), which does not appear in animals that have undergone ovariectomy prior to the onset of puberty, these mammalian ovarian glycolipids are also complementary to the anti-A/Tn cross-reactive Helix pomatia agglutinin, an eukaryotic defense protein, which has emerged from the egg coats of the snail and reveals its recently discovered O-GalNAc glycan. The hexameric structure of this primitive, invertebrate defense protein suggests an evolutionary relationship to the non-immune, mammalian defense protein or ancestral IgM molecule, which hypothetically obtains its complementarity from the early trans-species O-GalNAc glycosylation of proteins and subsequent GalNAc transferase depletion that completes the cell differentiation processes and causes the release of O-glycan-depleted, complementary proteins, such as secretory IgM revealing the structure of the volatilely expressed, “lost” glycan carrier through germline-specific serine residues. Consequently, the early or first O-GalNAc glycosylations of proteins appear metabolically related to those of the mucin-type, “aberrant” monosaccharide GalNAcα1-O-Ser/Thr-R, also referred to as the Tn antigen, and explain the anti-Tn cross-reactivity of anti-A-specific immunoglobulins and the pronounced occurrence of cross-reactive anti-Tn antibody in plasma from humans with histo (blood) group O. In fact, in human blood group O, A-allelic, phenotype-specific GalNAc glycosylation of plasma proteins does not occur, affecting the levels of the anti-Tn antibody, which may function as a growth regulator that, depending on its levels, initiates a complex process of growth inhibition through enzyme-substrate competition with subsequent trans-species O-GalNAc-glycosylations.
Additional file 1 of Fleshy or dry: transcriptome analyses reveal the genetic mechanisms underlying bract development in Ephedra
Creators: name: Zumajo-Cardona, Cecilia
name: Ambrose, Barbara A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Plant Biology

description: Additional file 1: Fig. S1. Ephedra pipeline. a Ephedra californica ovules and pollen cone. b Ephedra antisyphilitica ovules and pollen cone. c Bioinformatics pipeline used for the transcriptome data, divided into three main steps. Fig. S2. Total number of reads obtained in a Ephedra californica b Ephedra antisyphilitica. Fig. S3. E90N50 Statistics for a Ephedra californica and b) Ephedra antisyphilitica. Fig. S4. BUSCO analysis against the Embryophyta database in a Ephedra californica and b Ephedra antisyphilitica. More than 80% of the transcriptomes are completed for both species. Fig. S5. PCA analyses using all replicates. Ephedra californica at the top and Ephedra antisyphilitica at the bottom.
Natural anti-A and Tn-cross-reactive IgM arise from developmental O-GalNAc glycosylations.*
Creators: name: Arend, Peter
Publisher: name: figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Hematology
subject: Medicine
subject: Biochemistry
subject: Developmental Biology
subject: Zoology
subject: 60114 Systems Biology
subject: Structural Biology
subject: Stem Cells
subject: Cell Biology
subject: Genetics

description: When the O-GalNAc glycan-bearing ovarian glycolipids, discovered in the C57BL/10 mouse, are complementary to its syngeneic, anti-A-reactive immunoglobulin M (IgM), which does not appear in animals that have undergone ovariectomy prior to the onset of puberty, these mammalian ovarian glycolipids are also complementary to the anti-A/Tn cross-reactive Helix pomatia agglutinin, a moluscan defense protein, which has emerged from the egg coats of the snail and reveals its recently discovered O-GalNAc glycan. The hexameric structure of this primitive, invertebrate defense protein suggests an evolutionary relationship to the non-immune, mammalian defense protein or ancestral IgM molecule, which hypothetically obtains its complementarity from the early trans-species O-GalNAc glycosylation of proteins and subsequent GalNAc transferase depletion that completes the cell differentiation processes and causes the release of O-glycan-depleted, complementary proteins, such as secretory IgM revealing the structure of the volatilely expressed, “lost” glycan carrier through germline-specific serine residues. Consequently, the early or first O-GalNAc glycosylations of proteins appear metabolically related to those of the mucin-type, “aberrant” monosaccharide GalNAcα1-O-Ser/Thr-R, also referred to as the Tn antigen, and explain the anti-Tn cross-reactivity of anti-A-specific immunoglobulins and the pronounced occurrence of cross-reactive anti-Tn antibody in plasma from humans with histo (blood) group O. In fact, in human blood group O, A-allelic, phenotype-specific GalNAc glycosylation of plasma proteins does not occur, affecting the levels of the anti-Tn antibody, which may function as a growth regulator that, depending on its levels, initiates a complex process of growth inhibition through enzyme-substrate competition with subsequent trans-species O-GalNAc-glycosylations.
Natural anti-A and Tn-cross-reactive IgM arise from developmental O-GalNAc glycosylations.*
Creators: name: Arend, Peter
Publisher: name: figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Hematology
subject: Medicine
subject: Biochemistry
subject: Developmental Biology
subject: Zoology
subject: 60114 Systems Biology
subject: Structural Biology
subject: Stem Cells
subject: Cell Biology
subject: Genetics

description: When the O-GalNAc glycan-bearing ovarian glycolipids, discovered in the C57BL/10 mouse, are complementary to its syngeneic, anti-A-reactive immunoglobulin M (IgM), which does not appear in animals that have undergone ovariectomy prior to the onset of puberty, these mammalian ovarian glycolipids are also complementary to the anti-A/Tn cross-reactive Helix pomatia agglutinin, a molluscan defense protein, which has emerged from the egg coats of the snail and reveals its recently discovered O-GalNAc glycan. The hexameric structure of this primitive, invertebrate defense protein suggests an evolutionary relationship to the non-immune, mammalian defense protein or ancestral IgM molecule, which hypothetically obtains its complementarity from the early trans-species O-GalNAc glycosylation of proteins and subsequent GalNAc transferase depletion that completes the cell differentiation processes and causes the release of O-glycan-depleted, complementary proteins, such as secretory IgM revealing the structure of the volatilely expressed, “lost” glycan carrier through germline-specific serine residues. Consequently, the early or first O-GalNAc glycosylations of proteins appear metabolically related to those of the mucin-type, “aberrant” monosaccharide GalNAcα1-O-Ser/Thr-R, also referred to as the Tn antigen, and explain the anti-Tn cross-reactivity of anti-A-specific immunoglobulins and the pronounced occurrence of cross-reactive anti-Tn antibody in plasma from humans with histo (blood) group O. In fact, in human blood group O, A-allelic, phenotype-specific GalNAc glycosylation of plasma proteins does not occur, affecting the levels of the anti-Tn antibody, which may function as a growth regulator that, depending on its levels, initiates a complex process of growth inhibition through enzyme-substrate competition with subsequent trans-species O-GalNAc-glycosylations.
Standard Turkic C-Type Reduplications
Creators: name: Stachowski, Kamil
Publisher: name: figshare
Year: 2020
Subjects: subject: History
subject: Linguistics
subject: FOS: Languages and literature
subject: Language

description: The book examines partial interfixed reduplications in the standard Turkic languages.
Generally no longer productive, this type of reduplication served primarily to intensify adjectives and adverbs. The reduplicated anlaut was prepended to the the base, and a lexically determined consonant inserted in between, e.g. Tksh. kara ‘black’ → ka.p.kara ‘jet-black’, Trkm. gūry ‘dry’ → gu.s.gūry ‘completely dry’.
Unlike most previous works, this book considers the phenomenon comparatively across twenty modern languages, is based on possibly complete collections of examples, and approaches the subject from a diachronic perspective, combining etymological, historical-comparative, and quantitative methodology.
Additional file 1 of Discovery of genes positively modulating treatment effect using potential outcome framework and Bayesian update
Creators: name: Lee, Young Keun
name: Kim, Jisoo
name: Seo, Sung Wook
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. How to simulate data generation, demographics of cBioPortal dataset, demographics of CancerSCAN dataset, pseudocode of the C-search Algorithm, computational complexity
Natural anti-A and Tn-cross-reactive IgM arise from developmental O-GalNAc glycosylations.*
Creators: name: Arend, Peter
Publisher: name: figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Hematology
subject: Medicine
subject: Biochemistry
subject: Developmental Biology
subject: Zoology
subject: 60114 Systems Biology
subject: Structural Biology
subject: Stem Cells
subject: Cell Biology
subject: Genetics

description: When the O-GalNAc glycan-bearing ovarian glycolipids, discovered in the C57BL/10 mouse, are complementary to its syngeneic, anti-A-reactive immunoglobulin M (IgM), which does not appear in animals that have undergone ovariectomy prior to the onset of puberty, these mammalian ovarian glycolipids are also complementary to the anti-A/Tn cross-reactive Helix pomatia agglutinin, a molluscan defense protein, which has emerged from the egg coats of the snail and reveals its recently discovered O-GalNAc glycan. The hexameric structure of this primitive, invertebrate defense protein suggests an evolutionary relationship to the non-immune, mammalian defense protein or ancestral IgM molecule, which hypothetically obtains its complementarity from the early trans-species O-GalNAc glycosylation of proteins and subsequent GalNAc transferase depletion that completes the cell differentiation processes and causes the release of O-glycan-depleted, complementary proteins, such as secretory IgM revealing the structure of the volatilely expressed, “lost” glycan carrier through germline-specific serine residues. Consequently, the early or first O-GalNAc glycosylations of proteins appear metabolically related to those of the mucin-type, “aberrant” monosaccharide GalNAcα1-O-Ser/Thr-R, also referred to as the Tn antigen, and explain the anti-Tn cross-reactivity of anti-A-specific immunoglobulins and the pronounced occurrence of cross-reactive anti-Tn antibody in plasma from humans with histo (blood) group O. In fact, in human blood group O, A-allelic, phenotype-specific GalNAc glycosylation of plasma proteins does not occur, affecting the levels of the anti-Tn antibody, which may function as a growth regulator that, depending on its levels, initiates a complex process of growth inhibition through enzyme-substrate competition with subsequent trans-species O-GalNAc-glycosylations.
Standard Turkic C-Type Reduplications
Creators: name: Stachowski, Kamil
Publisher: name: figshare
Year: 2014
Subjects: subject: History
subject: Linguistics
subject: FOS: Languages and literature
subject: Language

description: The book examines partial interfixed reduplications in the standard Turkic languages.
Generally no longer productive, this type of reduplication served primarily to intensify adjectives and adverbs. The reduplicated anlaut was prepended to the the base, and a lexically determined consonant inserted in between, e.g. Tksh. kara ‘black’ → ka.p.kara ‘jet-black’, Trkm. gūry ‘dry’ → gu.s.gūry ‘completely dry’.
Unlike most previous works, this book considers the phenomenon comparatively across twenty modern languages, is based on possibly complete collections of examples, and approaches the subject from a diachronic perspective, combining etymological, historical-comparative, and quantitative methodology.
Natural anti-A and Tn-cross-reactive IgM arise from developmental O-GalNAc glycosylations.*
Creators: name: Arend, Peter
Publisher: name: figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Hematology
subject: Medicine
subject: Biochemistry
subject: Developmental Biology
subject: Zoology
subject: 60114 Systems Biology
subject: Structural Biology
subject: Stem Cells
subject: Cell Biology
subject: Genetics

description: When the O-GalNAc glycan-bearing ovarian glycolipids, discovered in the C57BL/10 mouse, are complementary to its syngeneic, anti-A-reactive immunoglobulin M (IgM), which does not appear in animals that have undergone ovariectomy prior to the onset of puberty, these mammalian ovarian glycolipids are also complementary to the anti-A/Tn cross-reactive Helix pomatia agglutinin, a molluscan defense protein, which has emerged from the egg coats of the snail and reflects the snail intrinsic O-GalNAc glycosylations. The hexameric structure of this primitive, invertebrate defense protein suggests an evolutionary relationship to the non-immune, mammalian defense protein or ancestral IgM molecule, which hypothetically obtains its complementarity from the early trans-species O-GalNAc glycosylation of proteins and subsequent GalNAc transferase depletion that completes the cell differentiation processes and causes the release of O-glycan-depleted, complementary proteins, such as secretory IgM revealing the structure of the volatilely expressed, “lost” glycan carrier through germline-specific serine residues. Consequently, the early or first O-GalNAc glycosylations of proteins appear metabolically related to those of the mucin-type, “aberrant” monosaccharide GalNAcα1-O-Ser/Thr-R, also referred to as the Tn antigen, and explain the anti-Tn cross-reactivity of anti-A-specific immunoglobulins and the pronounced occurrence of cross-reactive anti-Tn antibody in plasma from humans with histo (blood) group O. In fact, in human blood group O, A-allelic, phenotype-specific GalNAc glycosylation of plasma proteins does not occur, affecting the levels of the anti-Tn antibody, which may function as a growth regulator that, depending on its levels, initiates a complex process of growth inhibition through enzyme-substrate competition with subsequent trans-species O-GalNAc-glycosylations.
Natural anti-A and Tn-cross-reactive IgM arise from developmental O-GalNAc glycosylations.*
Creators: name: Arend, Peter
Publisher: name: figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Hematology
subject: Medicine
subject: Biochemistry
subject: Developmental Biology
subject: Zoology
subject: 60114 Systems Biology
subject: Structural Biology
subject: Stem Cells
subject: Cell Biology
subject: Genetics

description: While native blood group A-like glycans have not been demonstrated in prokaryotic microorganisms as a source of human “natural” anti-A isoagglutinin production, and trans-species, eukaryotic O-GalNAc-Ser/Thr glycosylations do not occur in bacteria, the O-GalNAc glycan-bearing ovarian glycolipids, discovered in C57BL/10 mice, are complementary to the syngeneic anti-A–reactive immunoglobulin M (IgM), which is not present in animals that have undergone ovariectomy prior to the onset of puberty. These mammalian ovarian glycolipids are complementary also to the anti-A/Tn cross-reactive Helix pomatia agglutinin (HPA), a molluscan defense protein, emerging from the coat proteins of fertilized eggs, and reflecting the intrinsic, reversible O-GalNAc glycosylation of the snail. The hexameric structure of this primitive invertebrate defense protein gives rise to speculation regarding an evolutionary relationship to the mammalian non-immune, anti-A-reactive immunoglobulin M (IgM) molecule. Hypothetically, this molecule obtains its complementarity from the first protein glycosylations occurring in eukaryotes by O-linked GalNAc, and subsequent transferase depletion and/or deglycosylation completing germ cell maturation and cell renewal. This causes the loss of glycosidic bonds and release of O-glycan-depleted complementary proteins, such as secretory IgM, revealing the structure of the volatilely expressed “lost” glycan carrier through germline-specific Ser residues. Consequently, the eukaryotic/developmental, first glycosylations of proteins appear metabolically related to that of the mucin-type, potentially “aberrant” monosaccharide GalNAcα1-O-Ser/Thr-R, also referred to as the Tn (T “nouvelle”) antigen, and explain the anti-Tn cross-reactivity of human innate or "natural" anti-A-specific isoagglutinin and the pronounced occurrence of cross-reactive anti-Tn antibody in plasma from humans with histo-blood group O. In fact, A-allelic, phenotype-specific GalNAc glycosylation of plasma proteins does not occur in human blood group O, affecting anti-Tn antibody levels, which may function as a growth regulator that contributes to a potential survival advantage of this group in the overall risk of developing cancer when compared with non-O blood groups.
Diglyme as a Promoter for the Electrochemical Formation of Quaternary Graphite Intercalation Compounds Containing two Different Types of Solvents
Creators: name: Son, Youhyun
name: Åvall, Gustav
name: Ferrero, Guillermo A.
name: Freytag, Annica
name: Escher, Ines
name: Janßen, Knut Arne
name: Jauregui, Maria
name: Saurel, Damien
name: Galceran Mestes, Montserrat
name: Adelhelm, Philipp
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: Graphite
subject: Sodium-ion batteries
subject: Co-intercalation
subject: q-GICs
subject: Electrochemistry
subject: 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten

description: Co-intercalation using ether-based electrolytes renders graphite as a promising anode material in sodium-ion batteries (SIBs). While most research on electrochemical solvent co-intercalation in graphite has focused on linear ethers such as mono-, di-, tri-, tetra-, and penta-glyme, we herein investigate the possibility of reversible electrochemical co-intercalation with alternative solvents, especially cyclic ethers tetrahydrofuran (THF) and 1,3-dioxolane (DOL), which show no signs of co-intercalation on their own. We demonstrate, however, that this reaction becomes feasible when incorporating diethylene glycol dimethyl ether (2G, diglyme) as an additive. Operando X-ray diffraction and ex-situ ss-NMR techniques are employed comprehensively to understand the co-intercalation reaction of these cyclic ethers, along with Na+-glymes, into graphite during cycling. When using these mixed electrolytes i. e., THF/2G and DOL/2G, the voltage profiles changes compared to the pure glyme-based electrolyte, while showing comparable specific capacities and good long-term durability. Overall, we propose that even trace amounts of diglyme prompt the co-intercalation of THF and DOL into graphite layers. This leads to the formation of quaternary graphite intercalation compounds (q-GICs), expanding beyond the realm of ternary graphite intercalation compounds (t-GICs).
Additional file 1 of Measuring aniseikonia and investigating neuroplasticity and image factors in amblyopia (MAGNIFY): study protocol for a randomised clinical trial
Creators: name: South, Jayshree
name: Gao, Tina
name: Calderwood, Melinda
name: Turuwhenua, Jason
name: Roberts, Paul
name: Lee, Arier
name: Collins, Andrew
name: Black, Joanna
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer

description: Additional file 1: Appendix 1 Parental/caregiver consent form. Appendix 2 Parent/caregiver participant information sheet. Appendix 3 Child assent form. Appendix 4 Child participant information sheet. Appendix 5 Trial registration data set
Przedmowa do antologii Shinsen waka
Creators: name: Olszewski, Krzysztof
name: Ki-No Tsurayuki
Publisher: name: figshare
Year: 2014
Subjects: Literature

description: The preface to a private anthology "Shinsen waka" (New Selection of Poems), compiled by Ki no Tsurayuki just after his returning from Tosa to the capital in 935. The original was written in Chinese.
Natural anti-A and Tn-cross-reactive IgM arise from developmental O-GalNAc glycosylations.*
Creators: name: Arend, Peter
Publisher: name: figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Hematology
subject: Medicine
subject: Biochemistry
subject: Developmental Biology
subject: Zoology
subject: 60114 Systems Biology
subject: Structural Biology
subject: Stem Cells
subject: Cell Biology
subject: Genetics

description: While native blood group A-like glycans have not been demonstrated in prokaryotic microorganisms as a source of human “natural” anti-A isoagglutinin production, and trans-species, eukaryotic O-GalNAc-Ser/Thr glycosylations do not occur in bacteria, the O-GalNAc glycan-bearing ovarian glycolipids, discovered in C57BL/10 mice, are complementary to the syngeneic anti-A-reactive immunoglobulin M (IgM), which is not present in animals that have undergone ovariectomy prior to the onset of puberty. These mammalian ovarian glycolipids are complementary also to the anti-A/Tn cross-reactive Helix pomatia agglutinin (HPA), a molluscan defense protein, emerging from the coat proteins of fertilized eggs and reflecting the snail-intrinsic, reversible O-GalNAc glycosylations. The hexameric structure of this primitive invertebrate defense protein gives rise to speculation regarding an evolutionary relationship to the mammalian non-immune, anti-A-reactive immunoglobulin M (IgM) molecule. Hypothetically, this molecule obtains its complementarity from the first step of protein glycosylations, initiated in eukaryotes by GalNAc via O-linkages, whereas subsequent transferase depletion and/or deglycosylation complete germ cell maturation and cell renewal. This causes the loss of glycosidic bonds and release of O-glycan-depleted proteins, such as complementary IgM, which reveals the structure of the volatilely expressed “lost” glycan carrier through germline-specific Ser residues. Consequently, the eukaryotic/developmental, first glycosylations of proteins appear metabolically related to that of the mucin-type, potentially “aberrant” monosaccharide GalNAcα1-O-Ser/Thr-R, also referred to as the Tn (T “nouvelle”) antigen, and explain the anti-Tn cross-reactivity of human innate or "natural" anti-A-specific isoagglutinin and the pronounced occurrence of cross-reactive anti-Tn antibody in plasma from humans with histo-blood group O. In fact, A-allelic, phenotype-specific GalNAc glycosylation of plasma proteins does not occur in human blood group O, affecting anti-Tn antibody levels, which may function as a growth regulator that contributes to a potential survival advantage of this group in the overall risk of developing cancer when compared with non-O blood groups.
Additional file 1 of Sex differences following percutaneous coronary intervention or coronary artery bypass surgery for acute myocardial infarction
Creators: name: Lin, Donna Shu-Han
name: Lin, Yu-Sheng
name: Lee, Jen-Kuang
name: Kao, Hsien-Li
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Additional file 1: Table S1. ICD-9 CM diagnostic codes for identifying diseases. Table S2. Demographics, clinical and surgical characteristics of men versus women in the propensity score matched cohort. Table S3. In-hospital outcomes of the women versus men in the cohort before propensity score matching. Table S4. Long-term outcomes of the women versus men in the cohort before propensity score matching. Table S5. Subgroup analysis (by diabetics) of long-term secondary outcomes of the women versus men in the propensity score matched group. Table S6. Subgroup analysis (by history of heart failure hospitalization) of long-term secondary outcomes of the women versus men in the propensity score matched group. Table S7. Subgroup analysis (by chronic kidney disease) of long-term secondary outcomes of the women versus men in the propensity score matched group
Additional file 1 of Congruent responses of vascular plant and ant communities to pastoral land-use abandonment in mountain areas throughout different biogeographic regions
Creators: name: Verdinelli, Marcello
name: Pittarello, Marco
name: Caria, Maria Carmela
name: Piga, Giovanna
name: Roggero, Pier Paolo
name: Marrosu, Gian Marco
name: Arrizza, Stefano
name: Fadda, Maria Leonarda
name: Lombardi, Giampiero
name: Lonati, Michele
name: Nota, Ginevra
name: Sitzia, Maria
name: Bagella, Simonetta
Publisher: name: figshare
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Additional file 1. Appendix S1. Schematic representation of surveys on vascular plants through the vertical point-quadrat method along four transects corresponding to four perpendicular radii of a circular plot. Appendix S2. Scheme of ant sampling design: four pitfall traps, 10 m distant from each other, were sunk into the soil and centred on each vegetation plot. Appendix S3. Ant dichotomous key reference list. Appendix S4. Ant species collected during the survey per each stage. Ant functional groups (FG): Subordinate Camponotini (Cm), Hot-climate Specialists (HCS), Cold-climate Specialists (CCS), Cryptic Species (Cr), Opportunists (Op), Specialised Predators (SP), and Generalised Myrmicinae (GM). Ant traits: Worker size (WS), Worker polymorphism (WP), Colony size (CS), Diet (D), Behavioural dominance (BD), Diurnality (Di), Foraging strategy (FS), Number of nests per colony (nN), Number of queens (nQ), Colony foundation (CF). For ant traits in species for which no data are reported in the literature, ten workers per species were randomly selected and measured for determining the WS; the mean thereof was used as a value for each species. Appendix S5. List of plant species found across the study sites associated with their Raunkiaer plant life form (Pignatti 2005), Forage type (Allen et al. 2011), Plant functional group, and the occurrence in the stages of the chronosequence. The latter is the combination of the life form and the forage type. Plant species nomenclature follows Pignatti et al. (2017).
Setting P-Donor Ligands into Context: An Application of the Ligand Knowledge Base (LKB) Approach
Creators: name: Fey, Natalie
name: Papadouli, Sofia
name: Pringle, Paul G.
name: Ficks, Arne
name: Fleming, James T.
name: Higham, Lee J.
name: Wallis, Jennifer F.
name: Carmichael, Duncan
name: Mézailles, Nicolas
name: Müller, Christian
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Cell Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences

description: GRAPHICAL ABSTRACT
Analysis of the ex situ conservation of the Greek endemic flora at national European and global scale and of its effectiveness in meeting GSPC Target 8
Creators: name: N. Krigas
name: V. Menteli
name: D. Vokou
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences
subject: Evolutionary Biology

description: We examine the extent to which the rich endemic flora of Greece, a country that belongs to the Mediterranean hotspot, and particularly that part facing an extinction risk, is effectively conserved ex situ. We detected 3,067 accessions of 523 taxa representing 37.2% of the Greek endemics in 213 botanic gardens (439 taxa) and 14 seed banks (344 taxa) of 36 countries; 46.7% of these accessions are in Greek institutions. Seeds are available for only 23.8% of the taxa in seed banks. Of the 558 threatened and near threatened endemics, 268 are conserved ex situ. Of these, 44.8% are accessioned in a single botanic garden and 48.9% in a single seed bank; in the latter, 25% are represented by a single accession number. Based on major concerns, for a taxon to be considered as effectively conserved ex situ, we propose that it be represented by no less than five accessions deposited in two institutions of two countries, at least. This criterion is met by only 6.4% of the taxa in SBs. There is still a long way to go so as to achieve Target 8 of the Global Strategy for Plant Conservation (GSPC).