cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Implementing Dose Management Systems in Radiology Departments: Pros and Cons
Creators: name: Vicente, Bianca
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Professional issues
subject: Radiographers
subject: Radioprotection / Radiation dose
subject: Conventional radiography
subject: CT
subject: Digital radiography
subject: Education
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: The increasing use of radiodiagnostic modalities has led to an increased focus and awareness on patient safety and consequent search for optimization of radiographer’s practices 1 . The Basic Safety and Standards Directive (BSSD), 2013/59/Euratom...
Quantum Zeno and Zeno-like effects in nitrogen vacancy centers
Creators: name: Qiu, Jing
name: Wang, Yang-Yang
name: Yin, Zhang-Qi
name: Zhang, Mei
name: Ai, Qing
name: Deng, Fu-Guo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a proposal to realize the quantum Zeno effect (QZE) and quantum Zeno-like effect (QZLE) in a proximal $\mathrm{^{13}C}$ nuclear spin by controlling a proximal electron spin of a nitrogen vacancy (NV) center. The measurement is performed by applying a microwave pulse to induce the transition between different electronic spin states. Under the practical experimental conditions, our calculations show that there exist both QZE and QZLE in a $^{13}$C nuclear spin in the vicinity of an NV center.
description: 9 pages, 2 figures; replot Fig. 2, accepted for Scientific Reports
Supplementary Material for Gilbert & Miles 2017 from Natural selection on thermal preference, critical thermal maxima and locomotor performance
Creators: name: Gilbert, Anthony L.
name: Miles, Donald B.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology

description: Climate change is resulting in a radical transformation of the thermal quality of habitats across the globe. Whereas species have altered their distributions to cope with changing environments, the evidence for adaptation in response to rising temperatures is limited. However, to determine the potential of adaptation in response to thermal variation, we need estimates of the magnitude and direction of natural selection on traits that are assumed to increase persistence in warmer environments. Most inferences regarding physiological adaptation are based on interspecific analyses, and those of selection on thermal traits are scarce. Here, we estimate natural selection on major thermal traits used to assess the vulnerability of ectothermic organisms to altered thermal niches. We detected significant directional selection favouring lizards with higher thermal preferences and faster sprint performance at their optimal temperature. Our analyses also revealed correlational selection between thermal preference and critical thermal maxima, where individuals that preferred warmer body temperatures with cooler critical thermal maxima were favoured by selection. Recent published estimates of heritability for thermal traits suggest that, in concert with the strong selective pressures we demonstrate here, evolutionary adaptation may promote long-term persistence of ectotherms in altered thermal environments.
A Genome-Wide Association Study of Overall Survival in Pancreatic Cancer Patients Treated with Gemcitabine in CALGB 80303
Creators: name: Glubb, Dylan
name: Giacomini, Kathleen M.
name: Schilsky, Richard L.
name: Friedman, Paula
name: Mushiroda, Taisei
name: Hurwitz, Herbert
name: Ratain, Mark J.
name: Cox, Nancy L.
name: Kindler, Hedy L.
name: Innocenti, Federico
name: Li, Liang
name: Nakamura, Yusuke
name: Zembutsu, Hitoshi
name: Owzar, Kouros
name: Wang, Liewei
name: Kubo, Michiaki
name: McLeod, Howard L.
name: Jiang, Chen
name: Hollis, Donna
name: Goldberg, Richard M.
name: Evans, Patrick
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: CALGB 80303 was a randomized, phase III study in advanced pancreatic cancer patients treated with gemcitabine plus either bevacizumab or placebo. We prospectively collected germline DNA and conducted a genome-wide association study (GWAS) using overall survival (OS) as the endpoint.
title: Assessing the applicability of trabecular bone score in osteoporosis diagnosis in patients with ankylosing spondylitis
Creators: name: Zuchowski, Pawel
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Musculoskeletal bone
subject: Absorptiometry / Bone densitometry
subject: Comparative studies
subject: Osteoporosis

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: The distinctive feature of ankylosing spondylitis (AS) is chronic inflammation of sacroiliac and vertebral joints. In the course of AS there develop a number of changes in the musculoskeletal system, e.g. the emergence of syndesmophytes and changes...
Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models
Creators: name: Pfefferle, Adam D.
name: Jin, Jian
name: Johnson, Soren M.
name: Dillon, Patrick M.
name: Combest, Austin J.
name: Darr, David B.
name: Zamboni, William C.
name: Duncan, James S.
name: Sharpless, Norman E.
name: Whittle, Martin C.
name: Johnson, Gary L.
name: Roberts, Patrick J.
name: Usary, Jerry E.
name: Perou, Charles M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Anticancer drug development is inefficient, but genetically engineered murine models (GEMM) and orthotopic, syngeneic transplants (OST) of cancer may offer advantages to in vitro and xenograft systems.
IDH1 and IDH2 Mutations in Tumorigenesis: Mechanistic Insights and Clinical Perspectives
Creators: name: Guan, Kun Liang
name: Ye, Dan
name: Xiong, Yue
name: Yang, Hui
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Genes encoding for isocitrate dehydrogenases 1 and 2, IDH1 and IDH2, are frequently mutated in multiple types of human cancer. Mutations targeting IDH1 and IDH2 result in simultaneous loss of their normal catalytic activity, the production of α-ketoglutarate (α-KG), and gain of a new function, the production of 2-hydroxyglutarate (2–HG). 2-HG is structurally similar to α-KG, and acts as an α-KG antagonist to competitively inhibit multiple α-KG-dependent dioxygenases, including both lysine histone demethylases (KDM) and the ten-eleven translocation (TET) family of DNA hydroxylases. Abnormal histone and DNA methylation are emerging as a common feature of tumors with IDH1 and IDH2 mutations and may cause altered stem cell differentiation and eventual tumorigenesis. Therapeutically, unique features of IDH1 and IDH2 mutations make them good biomarkers and potential drug targets.
(401265) Ann Mathers Park
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Restarted Hessenberg method for solving shifted nonsymmetric linear systems
Creators: name: Gu, Xian-Ming
name: Huang, Ting-Zhu
name: Yin, Guojian
name: Carpentieri, Bruno
name: Wen, Chun
name: Du, Lei
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65F10, 65F15, 15A06, 15A18

description: It is known that the restarted full orthogonalization method (FOM) outperforms the restarted generalized minimum residual (GMRES) method in several circumstances for solving shifted linear systems when the shifts are handled simultaneously. Many variants of them have been proposed to enhance their performance. We show that another restarted method, the restarted Hessenberg method [M. Heyouni, Méthode de Hessenberg Généralisée et Applications, Ph.D. Thesis, Université des Sciences et Technologies de Lille, France, 1996] based on Hessenberg procedure, can effectively be employed, which can provide accelerating convergence rate with respect to the number of restarts. Theoretical analysis shows that the new residual of shifted restarted Hessenberg method is still collinear with each other. In these cases where the proposed algorithm needs less enough CPU time elapsed to converge than the earlier established restarted shifted FOM, weighted restarted shifted FOM, and some other popular shifted iterative solvers based on the short-term vector recurrence, as shown via extensive numerical experiments involving the recent popular applications of handling the time fractional differential equations.
description: 19 pages, 7 tables. Some corrections for updating the references
Phase II Efficacy and Pharmacogenomic Study of Selumetinib (AZD6244; ARRY-142886) in Iodine-131 Refractory Papillary Thyroid Carcinoma with or without Follicular Elements
Creators: name: Hoskins, Janelle
name: Mehra, Ranee
name: Chung, Christine H.
name: Murphy, Barbara A.
name: Sheikh, Arif
name: Gilbert, Jill
name: Tanvetyanon, Tawee
name: Moore, Dominic T.
name: Lucas, Amy S.
name: Krzyzanowska, Monika K.
name: Hayward, Michele C.
name: Cohen, Roger B.
name: O'Connor, Wendi
name: Weck, Karen E.
name: Hayes, D. Neil
name: Cohen, Ezra E.W.
name: Zhao, Ni
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: A multicenter, open-label, phase II trial was conducted to evaluate the efficacy, safety, and tolerability of selumetinib in iodine-refractory papillary thyroid cancer (IRPTC).
title: Fingerprinting radiological training datasets by transparent imaging features (TI-score) to measure data suitability for generalizable deep learning applications
Creators: name: Dadras, Armin
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Artificial Intelligence
subject: Lung
subject: Thorax
subject: CT
subject: CT-Quantitative
subject: Neural networks
subject: CAD
subject: Computer Applications-Detection, diagnosis
subject: Segmentation
subject: Image verification
subject: Quality assurance
subject: Tissue characterisation

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: The increased usage of machine learning methods in medical imaging evoked criticism because it does not suffice the necessary safety requirements in medicine. Segmentation tasks especially need to work reliably in order to prevent errors in...
Supplementary Tables 1-5 and Supplementary Figures 1-2 from Male relatedness and familiarity are required to modulate male-induced harm to females in Drosophila.
Creators: name: Page, Sally Le
name: Irem Sepil
name: Flintham, Ewan
name: Pizzari, Tommaso
name: Carazo, Pau
name: Wigby, Stuart
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: All electronic supplementary material.
Predictive and Prognostic Roles of BRAF Mutation in Stage III Colon Cancer: Results from Intergroup Trial CALGB 89803
Creators: name: Meyerhardt, Jeffrey A.
name: Hollis, Donna
name: Bertagnolli, Monica M.
name: Hantel, Alexander
name: Saltz, Leonard B.
name: Mayer, Robert J.
name: Fuchs, Charles S.
name: Shima, Kaori
name: Goldberg, Richard M.
name: McCleary, Nadine J.
name: Schaefer, Paul
name: Whittom, Renaud
name: Benson III, Al B.
name: Spiegelman, Donna
name: Ng, Kimmie
name: Ogino, Shuji
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Alterations in the RAS-RAF-MAP2K (MEK)-MAPK signaling pathway are major drivers in colon and rectal carcinogenesis. In colorectal cancer, BRAF mutation is associated with microsatellite instability (MSI), and typically predicts inferior prognosis. We examined the effect of BRAF mutation on survival and treatment efficacy in patients with stage III colon cancer.
title: Accuracy of reporting the hyperdense middle cerebral artery sign
Creators: name: Khan, Muhammad Imran
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: CNS
subject: CT
subject: CT-Angiography
subject: Audit and standards
subject: Education and training
subject: Pathology

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: “Accuracy in identifying the hyperdense middle cerebral artery sign” within a large, DGH Radiology...
Responsiveness of Intrinsic Subtypes to Adjuvant Anthracycline Substitution in the NCIC.CTG MA.5 Randomized Trial
Creators: name: Parker, Joel S.
name: Perou, Charles M.
name: Levine, Mark N.
name: Leung, Samuel
name: Voduc, K. David
name: Davis, Carole
name: Bernard, Philip S.
name: Ellis, Matthew J.
name: Tu, Dongsheng
name: Davies, Sherri
name: Cheang, Maggie C.U.
name: Pritchard, Kathleen I.
name: Shepherd, Lois E.
name: Ebbert, Mark T.W.
name: Jiang, Shan
name: Stijleman, Inge J.
name: Nielsen, Torsten O.
name: Chia, Stephen K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Recent studies suggest that intrinsic breast cancer subtypes may differ in their responsiveness to specific chemotherapy regimens. We examined this hypothesis on NCIC.CTG MA.5, a clinical trial randomizing premenopausal women with node-positive breast cancer to adjuvant CMF (cyclophosphamide-methotrexate-fluorouracil) versus CEF (cyclophosphamide-epirubicin-fluorouracil) chemotherapy.
title: MRI in anoperineal hidradenitis suppurativa (HS) - imaging features of the disease and it’s complications
Creators: name: Mellou, Vasiliki
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Gastrointestinal tract
subject: Pelvis
subject: Soft tissues / Skin
subject: MR
subject: Abscess delineation
subject: Screening
subject: Fistula

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: -To demonstrate the MRI features of anoperineal hidradenitis suppurativa (HS) -To highlight imaging findings in keeping with deeper involvement and...
Quantum Implementation of Unitary Coupled Cluster for Simulating Molecular Electronic Structure
Creators: name: Shen, Yangchao
name: Zhang, Xiang
name: Zhang, Shuaining
name: Zhang, Jing-Ning
name: Yung, Man-Hong
name: Kim, Kihwan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Atomic Physics (physics.atom-ph)
subject: Chemical Physics (physics.chem-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: In classical computational chemistry, the coupled-cluster ansatz is one of the most commonly used $ab~initio$ methods, which is critically limited by its non-unitary nature. The unitary modification as an ideal solution to the problem is, however, extremely inefficient in classical conventional computation. Here, we provide the first experimental evidence that indeed the unitary version of the coupled cluster ansatz can be reliably performed in physical quantum system, a trapped ion system. We perform a simulation on the electronic structure of a molecular ion (HeH$^+$), where the ground-state energy surface curve is probed, energies of excited-states are studied and the bond-dissociation is simulated non-perturbatively. Our simulation takes advantages from quantum computation to overcome the intrinsic limitations in classical computation and our experimental results indicate that the method is promising for preparing molecular ground-states for quantum simulation.
description: 6 pages, 4 figures
Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells
Creators: name: Shourideh, Mojgan
name: Sartor, Oliver
name: Lorusso, Giovanni D.
name: Koochekpour, Shahriar
name: Azabdaftari, Gissou
name: Vessella, Robert L.
name: Subramani, Dhatchayini
name: Scioneaux, Ray
name: Mohler, James L.
name: Thompson, Hillary
name: Willard, Stacey S.
name: Attwood, Kristopher
name: Rezaei, Katayoon
name: Manhardt, Charles
name: Majumdar, Sunipa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: During glutaminolysis, glutamine is catabolized to glutamate and incorporated into citric acid cycle and lipogenesis. Serum glutamate levels were measured in patients with primary prostate cancer (PCa) or metastatic castrate-resistant PCa (mCRPCa) to establish clinical relevance. The effect of glutamate-deprivation or blockade by metabotropic glutamate receptor 1 (GRM1)-antagonists was investigated on PCa cells’ growth, migration, and invasion to establish biological relevance.
title: Time of addendum reporting to out-of-hours registrar CT reports.
Creators: name: Khan, Muhammad Imran
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Emergency
subject: CT
subject: Audit and standards
subject: Education
subject: Quality assurance

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Imaging plays a vital role in diagnosing and monitoring in range of diseases. On call radiology registrars report the out of hours CT scans, which are reviewed by consultant before releasing the final report with an addendum. We compared the time...
A Novel HLA-A*0201 Restricted Peptide Derived from Cathepsin G Is an Effective Immunotherapeutic Target in Acute Myeloid Leukemia
Creators: name: Rodriguez-Cruz, Tania
name: Molldrem, Jeffrey J.
name: Sukhumalchandra, Pariya
name: Hunsucker, Sally A.
name: Mittendorf, Elizabeth A.
name: Ruisaard, Kathryn
name: Sergeeva, Anna
name: Lizee, Gregory
name: Alatrash, Gheath
name: Armistead, Paul M.
name: Clise-Dwyer, Karen
name: Zhang, Mao
name: Ropp, Patricia A.
name: Al-Atrache, Zein
name: Jakher, Haroon
name: Enyenihi, Atim A.
name: Lu, Sijie
name: St. John, Lisa S.
name: Glish, Gary L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Immunotherapy targeting aberrantly expressed leukemia associated antigens (LAA) has shown promise in the management of acute myeloid leukemia (AML). However, because of the heterogeneity and clonal evolution that is a feature of myeloid leukemia, targeting single peptide epitopes has had limited success, highlighting the need for novel antigen discovery. In this study, we characterize the role of the myeloid azurophil granule protease cathepsin G (CG) as a novel target for AML immunotherapy.
Influences of Dark Energy and dark matter on Gravitational Time Advancement
Creators: name: Ghosh, Samrat
name: Bhadra, Arunava
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The effect of dark matter/energy on gravitational time advancement (negative effective time delay) has been investigated considering few dark energy/matter models including cosmological constant. It is found that dark energy gives only (positive) gravitational time delay irrespective of the position of the observer whereas pure Schwarzschild geometry leads to gravitational time advancement when the observer is situated at relatively stronger gravitational field point in the light trajectory. Consequently, there will be no time advancement effect at all at radial distances where gravitational field due to dark energy is stronger than the gravitational field of Schwarzschild geometry.
description: 7 pages, no figure
Cumulative Genetic Risk Predicts Platinum/Taxane-Induced Neurotoxicity
Creators: name: Winham, Stacey J.
name: He, Yijing
name: McLeod, Howard L.
name: Revollo, Jane Yen
name: Brown, Robert
name: Paul, Jim
name: Motsinger-Reif, Alison A.
name: Hertz, Daniel L.
name: McWhinney-Glass, Sarah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The combination of a platinum and taxane are standard of care for many cancers, but the utility is often limited due to debilitating neurotoxicity. We examined whether single nucleotide polymorphisms (SNPs) from annotated candidate genes will identify genetic risk for chemotherapy-induced neurotoxicity.
(401260) Annie Mathers
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supplementary Tables 1-5 and Supplementary Figures 1-2 from Male relatedness and familiarity are required to modulate male-induced harm to females in Drosophila
Creators: name: Page, Sally Le
name: Irem Sepil
name: Flintham, Ewan
name: Pizzari, Tommaso
name: Carazo, Pau
name: Wigby, Stuart
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: All electronic supplementary material.
Impact of Tumor Microenvironment and Epithelial Phenotypes on Metabolism in Breast Cancer
Creators: name: Brauer, Heather Ann
name: D'Arcy, Monica
name: Romàn-Pèrez, Erick
name: Perou, Charles M.
name: Lang, Lindsay J.
name: Troester, Melissa A.
name: Casbas-Hernandez, Patricia
name: Freemerman, Alex J.
name: Makowski, Liza
name: Hoadley, Katherine A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Cancer cells have altered metabolism, with increased glucose uptake, glycolysis, and biomass production. This study performed genomic and metabolomic analyses to elucidate how tumor and stromal genomic characteristics influence tumor metabolism.
Murine Microenvironment Metaprofiles Associate with Human Cancer Etiology and Intrinsic Subtypes
Creators: name: Nguyen, David H.
name: Balmain, Allan
name: Mao, Jian Hua
name: Perou, Charles M.
name: Fredlund, Erik
name: Zhao, Wei
name: Barcellos-Hoff, Mary Helen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Ionizing radiation is a well established carcinogen in rodent models and a risk factor associated with human cancer. We developed a mouse model that captures radiation effects on host biology by transplanting unirradiated Trp53 null mammary tissue to sham or irradiated hosts. Gene expression profiles of tumors that arose in irradiated mice are distinct from those that arose in naïve hosts. We asked whether expression metaprofiles could discern radiation-preceded human cancer or be informative in sporadic breast cancers.
A note on oscillating strings in $AdS_3 \times S^3$ with mixed three-form fluxes
Creators: name: Banerjee, Aritra
name: Panigrahi, Kamal L.
name: Samal, Manoranjan
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a detailed study of the pulsating string solutions in AdS3 x S3 supported by both RR and NS-NS fluxes. This background has recently been proved to be integrable. We find the dispersion relation between the energy, oscillation number and other conserved charges when the NS-NS flux turned on is small. We further discuss the fate of the string solutions in pure RR and NS-NS cases.
description: 26 pages, version to appear in JHEP
title: Solitary necrotic nodules of the liver: appearance on different imaging modalities
Creators: name: Hernandez Herrero, Mariola
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: Liver
subject: CT
subject: MR
subject: Ultrasound
subject: Diagnostic procedure
subject: Inflammation

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To review the imaging characteristics of solitary necrotic nodules of the...
Supplementary information from Earthquake sequence simulations with measured properties for JFAST core samples.
Creators: name: Noda, Hiroyuki
name: Sawai, Michiyo
name: Bunichiro Shibazaki
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Geophysics

description: This file includes parameters of the fault constitutive law used in the present study and detailed description of a catastrophic earthquake produced in a simulation.
Phase I Study of Pazopanib in Patients with Advanced Solid Tumors and Hepatic Dysfunction: A National Cancer Institute Organ Dysfunction Working Group Study
Creators: name: Shibata, Stephen I.
name: Lau, S. Cecilia
name: Suttle, A. Benjamin
name: Rudek, Michelle A.
name: Belani Leena Gandhi, Chandra P.
name: Kummar, Shivaani
name: Ivy, S. Percy
name: Dowlati, Afshin
name: Synold, Timothy W.
name: O'Neil, Bert H.
name: Chung, Vincent
name: Longmate, Jeffrey A.
name: Mulkerin, Daniel L.
name: Lenz, Heinz Josef
name: LoRusso, Patricia
name: Sarantopoulos, John
name: Harvey, R. Donald
name: Hamilton, Anne L.
name: Newman, Edward M.
name: Ottesen, Lone H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Pazopanib is a potent, multi-targeted receptor tyrosine kinase inhibitor; however, there is limited information regarding the effects of liver function on pazopanib metabolism and pharmacokinetics (PK). The objective of this study was to establish the maximum tolerated dose (MTD) and PK profile of pazopanib in patients with varying degrees of hepatic dysfunction.
Phase II Study of Lutetium-177-Labeled Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody J591 for Metastatic Castration-Resistant Prostate Cancer
Creators: name: Taskar, Neeta Pandit
name: Scher, Howard I.
name: Bander, Neil H.
name: Larson, Steve
name: Nanus, David M.
name: Osborne, Joseph
name: Goldsmith, Stanley J.
name: Morris, Michael
name: Christos, Paul
name: Tagawa, Scott T.
name: Milowsky, Matthew I.
name: Vallabhajosula, Shankar
name: Akhtar, Naveed H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: To assess the efficacy of a single infusion of radiolabeled anti-prostate specific membrane antigen monoclonal antibody J591 (177Lu-J591) by PSA decline, measurable disease response, and survival.
The Gibbs paradox revisited from the fluctuation theorem with absolute irreversibility
Creators: name: Murashita, Yûto
name: Ueda, Masahito
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The inclusion of the factor $\ln (1/N!)$ in the thermodynamic entropy proposed by Gibbs is shown to be equivalent to the validity of the fluctuation theorem with absolute irreversibility for gas mixing.
description: 5 pages, 2 figures
title: C-arm x-ray systems with CMOS detector technology: dose reduction and image quality improvement in routine clinical use
Creators: name: Oberhofer, Nadia
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Radiation physics
subject: Radioprotection / Radiation dose
subject: Fluoroscopy
subject: Dosimetry
subject: Instrumentation
subject: Technical aspects
subject: Occupational / Environmental hazards

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: In many clinical settings, mobile c-arm x-ray devices are used for performing fluoroscopic imaging, including light interventional procedures. Until recently, the standard technology for digital detectors was represented by amorphous silicium flat...
(401261) Mary Park
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supplementary information from Earthquake sequence simulations with measured properties for JFAST core samples
Creators: name: Noda, Hiroyuki
name: Sawai, Michiyo
name: Bunichiro Shibazaki
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Geophysics

description: This file includes parameters of the fault constitutive law used in the present study and detailed description of a catastrophic earthquake produced in a simulation.
Phase II Trial of Bicalutamide in Patients with Androgen Receptor-Positive, Estrogen Receptor-Negative Metastatic Breast Cancer
Creators: name: Gonzalez, Joseph M.
name: Carey, Lisa A.
name: Akhtar, Arooj
name: Nabell, Lisle
name: Giri, Dilip D.
name: Feigin, Kimberly N.
name: Doane, Ashley S.
name: Moynahan, Mary Ellen
name: Forero, Andres
name: Blackwell, Kimberly
name: Stearns, Vered
name: Liu, Minetta C.
name: Traina, Tiffany A.
name: Momen, Lamia F.
name: Patil, Sujata
name: Rugo, Hope
name: Isakoff, Steven J.
name: Ingle, James N.
name: Tolaney, Sara
name: Hudis, Clifford A.
name: Danso, Michael
name: Gucalp, Ayca
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Patients with hormone receptor–negative breast cancer generally do not benefit from endocrine-targeted therapies. However, a subset with androgen receptor (AR) expression is predicted to respond to antiandrogen therapies. This phase II study explored bicalutamide in AR-positive, estrogen receptor (ER), and progesterone receptor (PgR)-negative metastatic breast cancer.
(401262) Alexander Bruce Buist
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supplementary Figures and Tables from Substrate-triggered position switching of TatA and TatB during Tat transport in Escherichia coli.
Creators: name: Habersetzer, Johann
name: Moore, Kristoffer
name: Cherry, Jon
name: Buchanan, Grant
name: Stansfeld, Phillip J.
name: Palmer, Tracy
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology

description: These are uploaded as a document along with the manuscript files
The coupling of Non-linear Supersymmetry to Supergravity
Creators: name: Antoniadis, Ignatios
name: Markou, Chrysoula
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the coupling of non-linear supersymmetry to supergravity. The goldstino nilpotent superfield of global supersymmetry coupled to supergravity is described by a geometric action of the chiral curvature superfield R subject to the constraint (R-λ)^2=0 with an appropriate constant λ. This constraint can be found as the decoupling limit of the scalar partner of the goldstino in a class of f(R) supergravity theories.
description: 15 pages, minor changes, version to be published in EPJC
Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Creators: name: Darr, David
name: Liu, Mei
name: Jordan, Jamie
name: Bridges, Arlene
name: Roberts, Patrick J.
name: Zhao, Wei
name: Sharpless, Norman E.
name: Zamboni, William
name: Rosen, Jeffrey M.
name: Balletta, Lorraine
name: Herschkowitz, Jason I.
name: Perou, Charles M.
name: Cheang, Maggie C.U.
name: Prat, Aleix
name: Karginova, Olga
name: Usary, Jerry
name: Combest, Austin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: To use genetically engineered mouse models (GEMMs) and orthotopic syngeneic murine transplants (OSTs) to develop gene-expression based predictors of response to anti-cancer drugs in human tumors. These mouse models offer advantages including precise genetics and an intact microenvironment/immune system.
Fast optimization of Multithreshold Entropy Linear Classifier
Creators: name: Jozefowicz, Rafal
name: Czarnecki, Wojciech Marian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Multithreshold Entropy Linear Classifier (MELC) is a density based model which searches for a linear projection maximizing the Cauchy-Schwarz Divergence of dataset kernel density estimation. Despite its good empirical results, one of its drawbacks is the optimization speed. In this paper we analyze how one can speed it up through solving an approximate problem. We analyze two methods, both similar to the approximate solutions of the Kernel Density Estimation querying and provide adaptive schemes for selecting a crucial parameters based on user-specified acceptable error. Furthermore we show how one can exploit well known conjugate gradients and L-BFGS optimizers despite the fact that the original optimization problem should be solved on the sphere. All above methods and modifications are tested on 10 real life datasets from UCI repository to confirm their practical usability.
description: Presented at Theoretical Foundations of Machine Learning 2015 (http://tfml.gmum.net), final version published in Schedae Informaticae Journal
(401258) James Whitehead
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Monte-Carlo approach to particle-field interactions and the kinetics of the chiral phase transition
Creators: name: Greiner, Carsten
name: Wesp, Christian
name: van Hees, Hendrik
name: Meistrenko, Alex
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The kinetics of the chiral phase transition is studied within a linear quark-meson-$σ$ model, using a Monte-Carlo approach to semiclassical particle-field dynamics. The meson fields are described on the mean-field level and quarks and antiquarks as ensembles of test particles. Collisions between quarks and antiquarks as well as the $q\overline{q}$ annihilation to $σ$ mesons and the decay of $σ$ mesons is treated, using the corresponding transition-matrix elements from the underlying quantum field theory, obeying strictly the rule of detailed balance and energy-momentum conservation. The approach allows to study fluctuations without making ad hoc assumptions concerning the statistical nature of the random process as necessary in Langevin-Fokker-Planck frameworks.
description: 7 pages, 7 figures, contribution to the proceedings of the 31st Winter Workshop on Nuclear Dynamics 2015
Supplementary Figures and Tables from Substrate-triggered position switching of TatA and TatB during Tat transport in Escherichia coli
Creators: name: Habersetzer, Johann
name: Moore, Kristoffer
name: Cherry, Jon
name: Buchanan, Grant
name: Stansfeld, Phillip J.
name: Palmer, Tracy
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology

description: These are uploaded as a document along with the manuscript files
On the consistency of Multithreshold Entropy Linear Classifier
Creators: name: Czarnecki, Wojciech Marian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Multithreshold Entropy Linear Classifier (MELC) is a recent classifier idea which employs information theoretic concept in order to create a multithreshold maximum margin model. In this paper we analyze its consistency over multithreshold linear models and show that its objective function upper bounds the amount of misclassified points in a similar manner like hinge loss does in support vector machines. For further confirmation we also conduct some numerical experiments on five datasets.
description: Presented at Theoretical Foundations of Machine Learning 2015 (http://tfml.gmum.net), final version published in Schedae Informaticae Journal
Relationship of Mammographic Density and Gene Expression: Analysis of Normal Breast Tissue Surrounding Breast Cancer
Creators: name: Johnson, Nicole B.
name: Troester, Melissa A.
name: Sherman, Mark E.
name: Boyd, Norman F.
name: Gierach, Gretchen L.
name: Williams, Tyisha
name: Wesolowska, Ewa
name: Figueroa, Jonine D.
name: Lissowska, Jolanta
name: Sandhu, Rupninder
name: Sun, Xuezheng
name: Midkiff, Bentley R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Previous studies of breast tissue gene expression have demonstrated that the extratumoral microenvironment has substantial variability across individuals, some of which can be attributed to epidemiologic factors. To evaluate how mammographic density (MD) and breast tissue composition relate to extratumoral microenvironment gene expression, we used data on 121 breast cancer patients from the population-based Polish Women's Breast Cancer Study.
title: An Audit of clinical review workstation standards and guidance on optimising the clinical review environment for interpretating x-rays; a single centre experience
Creators: name: O'Donovan, Sarah Kate
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Radiation physics
subject: Radiographers
subject: Thorax
subject: CT
subject: Digital radiography
subject: Audit and standards
subject: Education
subject: Physics
subject: Education and training
subject: Quality assurance

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: As junior doctors, many of us are asked to review radiological images in the wards. While all of these images will be officially signed off by a radiologist, junior doctors are often asked in the interim to review these images and formulate...
title: 3D biomodels and virtual surgical planning: what radiologists need to know.
Creators: name: ZABALA, Silvina
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Computer applications
subject: Professional issues
subject: Radiographers
subject: CT
subject: Image manipulation / Reconstruction
subject: MR
subject: Computer Applications-3D
subject: Computer Applications-General
subject: Education
subject: Education and training
subject: Quality assurance

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: This work reviews the main features and clinical applications of 3D biomodels, virtual surgical planning and 3D printing technologies. Image requirements to obtain quality 3D biomodels are discussed as well as the key role of radiologists in this...
Revisiting the combinatorics of the 2D Ising model
Creators: name: Chelkak, Dmitry
name: Cimasoni, David
name: Kassel, Adrien
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: Mathematical Physics (math-ph)
subject: Probability (math.PR)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We provide a concise exposition with original proofs of combinatorial formulas for the 2D Ising model partition function, multi-point fermionic observables, spin and energy density correlations, for general graphs and interaction constants, using the language of Kac-Ward matrices. We also give a brief account of the relations between various alternative formalisms which have been used in the combinatorial study of the planar Ising model: dimers and Grassmann variables, spin and disorder operators, and, more recently, s-holomorphic observables. In addition, we point out that these formulas can be extended to the double-Ising model, defined as a pointwise product of two Ising spin configurations on the same discrete domain, coupled along the boundary.
description: Minor change in the notation (definition of eta). 55 pages, 4 figures
Scaling Distances on Finitely Ramified Fractals
Creators: name: Peirone, Roberto
Publisher: name: arXiv
Year: 2015
Subjects: subject: Metric Geometry (math.MG)
subject: FOS: Mathematics
subject: 28A80, 05C12, 15B48

description: In previous papers by A. Kameyama and by J. Kigami distances on fractals have been discussed having two different but similar properties. One property is that the maps defining the fractal are Lipschitz of prescribed constants less than 1, the other is that the diameters of the copies of the fractal are asymptotic to prescribed scaling factors. In this paper, on a large class of finitely ramified fractals, we prove that these two problems are equivalent and give a necessary and sufficient condition for the existence of such distances. Such a condition is expressed in terms of asymptotic behavior of the product of certain matrices associated to the fractal.
description: 30 pages
Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional Class
Creators: name: Gao, Jingjing
name: Brennan, Cameron W.
name: Lehman, Norman L.
name: Miller, C. Ryan
name: Aldape, Kenneth D.
name: Park, Yuna
name: Moreno, Carlos S.
name: Mikkelsen, Tom
name: Cohen, Mark L.
name: McLendon, Roger E.
name: Caleb Rutledge, W.
name: Kong, Jun
name: Saltz, Joel H.
name: Brat, Daniel J.
name: Gutman, David A.
name: Appin, Christina
name: Schniederjan, Matthew J.
name: Scarpace, Lisa
name: Cooper, Lee A.D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Tumor-infiltrating lymphocytes (TILs) have prognostic significance in many cancers, yet their roles in glioblastoma (GBM) have not been fully defined. We hypothesized TILs in GBM are associated with molecular alterations, histologies and survival.
(401259) John Stewart
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Clinical Implications of Phosphorylated STAT3 Expression in De Novo Diffuse Large B-cell Lymphoma
Creators: name: Richards, Kristy L.
name: Huh, Jooryung
name: Zu, Youli
name: Møller, Michael B.
name: Winter, Jane N.
name: Ponzoni, Maurilio
name: Bertoni, Francesco
name: Farnen, John P.
name: Orazi, Attilio
name: Tzankov, Alexandar
name: Zhao, Xiaoying
name: Manyam, Ganiraju C.
name: Montes-Moreno, Santiago
name: Hsi, Eric D.
name: Dybkær, Karen
name: Ok, Chi Young
name: Xu-Monette, Zijun Y.
name: Chen, Jiayu
name: Bhagat, Govind
name: Visco, Carlo
name: Piris, Miguel A.
name: Choi, William W.L.
name: Van Krieken, J. Han
name: Li, Ling
name: Medeiros, L. Jeffrey
name: Chiu, April
name: Young, Ken H.
name: Ferreri, Andrés J.M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Activated signal transducer and activator of transcription 3 (STAT3) regulates tumor growth, invasion, cell proliferation, angiogenesis, immune response and survival. Data regarding expression of phosphorylated (activated) STAT3 in diffuse large B-cell lymphoma (DLBCL) and the impact of phosphorylated STAT3 (pSTAT3) on prognosis are limited.
title: Communication dose exposure for common radiological procedures: what the patients would like know
Creators: name: Salerno, Sergio
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Radioprotection / Radiation dose
subject: Conventional radiography
subject: CT
subject: Mammography
subject: Radiation safety
subject: Quality assurance

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: The increased use of radiological procedures, both for diagnostic and therapeutic purposes, imposes adequate information to the patient about the radiation dose. This information right was enhanced by some national and international organizations....