cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Event Log Sampling for Predictive Monitoring
Creators: name: Sani, Mohammadreza Fani
name: Vazifehdoostirani, Mozhgan
name: Park, Gyunam
name: Pegoraro, Marco
name: van Zelst, Sebastiaan J.
name: van der Aalst, Wil M. P.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Predictive process monitoring is a subfield of process mining that aims to estimate case or event features for running process instances. Such predictions are of significant interest to the process stakeholders. However, state-of-the-art methods for predictive monitoring require the training of complex machine learning models, which is often inefficient. This paper proposes an instance selection procedure that allows sampling training process instances for prediction models. We show that our sampling method allows for a significant increase of training speed for next activity prediction methods while maintaining reliable levels of prediction accuracy.
description: 7 pages, 1 figure, 4 tables, 34 references
Feasibility of nowcasting SDG indicators: a comprehensive survey
Creators: name: Hopp, Daniel
name: Fu, Emily
name: Peltola, Anu
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computers and Society (cs.CY)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: The 2030 Agenda and accompanying Sustainable Development Goals (SDGs) are vital in guiding national and global policy. However, many of the SDG indicators used to measure progress toward those goals suffer from long publication lags. Nowcasting has the potential to address this problem and generate more timely estimates of those indicators. This paper provides resources for achieving that potential by 1) carrying out a comprehensive nowcasting feasibility survey of all SDG indicators to assess their potential to be nowcast, and 2) performing a case study of indicator 9.4.1 to illustrate and shed light on the process of performing a nowcasting exercise. There exist 231 SDG indicators, but due to only examining Tier 1 indicators and the fact that many indicators have multiple sub-indicators, 362 indicators and sub-indicators were eventually surveyed. Of those 362, 150 were found highly likely to be suitable candidates for nowcasting, 87 were found to be likely, and 125 were found to be unsuitable.
description: 2 tables, 3 figures, 74 pages
Impact of renal function on ischemic stroke and major bleeding rates in nonvalvular atrial fibrillation patients treated with warfarin or rivaroxaban: a retrospective cohort study using real-world evidence
Creators: name: Weir, Matthew R
name: Berger, Jeffrey S.
name: Ashton, Veronica
name: Laliberté, François
name: Brown, Kip
name: Lefebvre, Patrick
name: Schein, Jeffrey
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: Hematology

description: Objectives: Renal dysfunction is associated with increased risk of cardiovascular disease, and is an independent predictor of stroke and systemic embolism. Nonvalvular atrial fibrillation (NVAF) patients with renal dysfunction may face particularly high risk of thromboembolism and bleeding. The current retrospective cohort study was designed to assess the impact of renal function on ischemic stroke and major bleeding rates in NVAF patients in the real-world setting (outside a clinical trial). Methods: Medical claims and Electronic Health Record were retrieved retrospectively from Optum’s Integrated Claims-Clinical de-identified dataset from May 2011 to August 2014. Patients with NVAF treated with warfarin (2,468) or rivaroxaban (1,290) were selected. Each treatment cohort was stratified by baseline estimated creatinine clearance (eCrCl) levels. Confounding adjustments were made using inverse probability of treatment weights (IPTW). Incidence rates and hazard ratios of ischemic stroke and major bleeding events were calculated for both cohorts. Results: Overall, patients treated with rivaroxaban had an ischemic stroke incidence rate of 1.9 per 100 person-years (PY) while patients treated with warfarin had a rate of 4.2 per 100 PY (HR = 0.41 [0.21-0.80], p = 0.009). Rivaroxaban patients with an eCrCl below 50 mL/min (N = 229) had an ischemic stroke rate of 0.8 per 100 PY, while the rate for the warfarin cohort (N = 647) was 6.0 per 100 PY (HR = 0.09 [0.01-0.72], p = 0.02). For renal function levels (i.e., eCrCl 50-80 and ≥80 mL/min) HRs indicated no statistically significant differences in ischemic stroke risks. Bleeding events did not differ significantly between cohorts stratified by renal function. Conclusions: Ischemic stroke rates were significantly lower in the overall NVAF population for rivaroxaban vs warfarin users, including patients with eCrCl below 50 mL/min. For all renal function groups, major bleeding risks were not statistically different between treatment groups.
Additional file 1 of Cross-validation study between the HRRT and the PET component of the SIGNA PET/MRI system with focus on neuroimaging
Creators: name: Mannheim, Julia G.
name: Cheng, Ju-Chieh (Kevin)
name: Vafai, Nasim
name: Shahinfard, Elham
name: English, Carolyn
name: McKenzie, Jessamyn
name: Zhang, Jing
name: Barlow, Laura
name: Sossi, Vesna
Publisher: name: figshare
Year: 2021
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1: Supplementary Figure 1: Representative images of the image quality phantom data for different reconstruction parameters. Color scales of the images were normalized based on the average background value multiplied by the respective sphere to background ratio. Supplementary Figure 2: RCs (a) and %BG variability (b) as a function of sphere diameter for the image quality phantom. PET/MR data were reconstructed with TOF, TOF with filter, TOF with PSF, and TOF with PSF and filter. 2 iterations and 28 subsets were used, respectively (GE recommendation for phantom data). Note the gap between spheres marks cold vs. hot spheres. Supplementary Figure 3: RCs (%) of the PET/MR (a) as a function of sphere diameter for the contrast phantom with (solid lines) and without TOF (dotted lines). Comparison of RCs (b) without TOF of the PET/MR (solid lines) to the HRRT (dotted lines). Note the gap between spheres marks cold vs. hot spheres. Supplementary Figure 4: RCs (%) (PET/MR (a), HRRT (b)) versus sphere diameter for the contrast phantom. Data were analyzed with a single slice ROI (solid lines), the standard NEMA analysis method, and with a spherical VOI matching the physical sphere diameter (dotted lines). Note the gap between spheres marks cold vs. hot spheres. Supplementary Figure 5: Voxel-wise correlation of the HRRT to PET/MR activity concentration for each subject ([11C]DTBZ, [18F]FDG, [11C]raclopride). The black line indicates the identity line, the red dotted line displays the linear regression of the values with the corresponding R2. Supplementary Table 1: RCs (a) and %BG variability (b) for the image quality phantom scanned on the PET/MR. Supplementary Table 2: RCs for the contrast phantom scanned on the PET/MR and HRRT. PET/MR data were reconstructed with and without TOF information.
title: Nobiletin affects circadian rhythms and oncogenic characteristics in a cell-depending manner
Creators: name: Lellupitiyage Don, Sujeewa S.
name: Robertson, Kelly L.
name: Lin, Hui-Hsien
name: Labriola, Caroline
name: Harrington, Mary E.
name: Taylor, Stephanie R.
name: Farkas, Michelle E.
Publisher: name: University of Massachusetts Amherst
Year: 2020

description: The natural product nobiletin is a small molecule, widely studied with regard to its therapeutic effects, including in cancer cell lines and tumors. Recently, nobiletin has also been shown to affect circadian rhythms via their enhancement, resulting in protection against metabolic syndrome. We hypothesized that nobiletin’s anti-oncogenic effects, such as prevention of cell migration and formation of anchorage independent colonies, are correspondingly accompanied by modulation of circadian rhythms. Concurrently, we wished to determine whether the circadian and anti-oncogenic effects of nobiletin differed across cancer cell lines. In this study, we assessed nobiletin’s circadian and therapeutic characteristics to ascertain whether these effects depend on cell line, which here also varied in terms of baseline circadian rhythmicity. Three cell culture models where nobiletin’s effects on cell proliferation and migration have been studied previously were evaluated: U2OS (bone osteosarcoma), which possesses robust circadian rhythms; MCF7 (breast adenocarcinoma), which has weak circadian rhythms; and MDA-MB-231 (breast adenocarcinoma), which is arrhythmic. We found that circadian, migration, and proliferative effects following nobiletin treatment were subtle in the U2OS and MCF7 cells. On the other hand, changes were clear in MDA-MB-231s, where nobiletin rescued rhythmicity and substantially reduced oncogenic features, specifically two-dimensional cell motility and anchorage-independent growth. Based on these results and those previously described, we posit that the effects of nobiletin are indeed cell-type dependent, and that a positive correlation may exist between nobiletin’s circadian and therapeutic effects.
Additional file 3: of New insights into the evolution and functional divergence of the SWEET family in Saccharum based on comparative genomics
Creators: name: Hu, Weichang
name: Hua, Xiuting
name: Zhang, Qing
name: Wang, Jianping
name: Shen, Qiaochu
name: Zhang, Xingtan
name: Wang, Kai
name: Yu, Qingyi
name: Lin, Yann-Rong
name: Ming, Ray
name: Zhang, Jisen
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: A schematic diagram for the relationship of the four clades of the phylogenetic tree constructed by the ML method. (PDF 42 kb)
Райковецький археологічний комплекс та перспективи сучасних науково-інформаційних технологій.
Creators: name: Томашевський, Андрій
Publisher: name: figshare
Year: 2017
Subjects: Archaeology

description: Томашевський А.П. Райковецький археологічний комплекс та перспективи сучасних науково-інформаційних технологій.// Бердичівська земля в контексті історії України. Науковий збірник “Велика Волинь”, т.19. - Житомир, 1999. - С. 57 - 61
Site-dependent Local Spin Susceptibility and Low-energy Excitation in a Weyl Semimetal WTe$_2$
Creators: name: Yokoo, Toshiki
name: Watanabe, Yukihiro
name: Kumazaki, Masashi
name: Itoh, Masayuki
name: Shimizu, Yasuhiro
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Site-dependent local spin susceptibility is investigated with $^{125}$Te nuclear magnetic resonance in a Weyl semimetal WTe$_2$. The nuclear spin-lattice relaxation rate $1/T_1T$ shows a dependence of the square of temperature $T$ at high temperatures, followed by a constant behavior below 50 K. The temperature dependence features Weyl fermions appearing around the linearly crossing bands. The Knight shift $K$ scales to the square root of $1/T_1T$, corroborating a predominant spin contribution in low-lying excitation. The observed dependence of $K$ and $1/T_1T$ on the four Te sites shows the site-dependent electron correlation and density of states. The angular profile of the NMR spectrum gives the anisotropic hyperfine coupling tensor, consistent with $5p$ hole occupations on Te sites.
description: 6 pages, 5 figures
Additional file 4: of New insights into the evolution and functional divergence of the SWEET family in Saccharum based on comparative genomics
Creators: name: Hu, Weichang
name: Hua, Xiuting
name: Zhang, Qing
name: Wang, Jianping
name: Shen, Qiaochu
name: Zhang, Xingtan
name: Wang, Kai
name: Yu, Qingyi
name: Lin, Yann-Rong
name: Ming, Ray
name: Zhang, Jisen
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: An unrooted tree using SWEET amino acid sequences from sugarcane, sorghum, maize and rice SWEET genes and the MtN3_slv domain architecture of those proteins. (PDF 2012 kb)
On the free rotation of a polarized spinning-top as a test of the correct radiation reaction torque
Creators: name: Duviryak, Askold
Publisher: name: arXiv
Year: 2022
Subjects: subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: The formula for dipole radiation reaction torque acting on a system of charges, and the Larmor-like formula for the angular momentum loss by this system, differ in the time derivative term which is the analogue of the Schott term in the energy loss problem. In the well-known textbooks this discrepancy is commonly avoided via neglect of the Schott term, and the Larmor-like formula is preferred. In the present paper both formulae are used to derive two different equations of motion of a polarized spinning-top. Both equations are integrable for the symmetric top and lead to quite different solutions. That one following from the Larmor-like formula is physically unplausible, in contrast to another one. This result is accorded with the reinterpretation of Larmor's formula discussed recently in the pedagogical literature. It is appeared, besides, that the Schott term is of not only academic significance, but it may determine the behavior of polarized micro- and nanoparticles in nature or future experiments.
description: 14 pages, 2 figures
Low Frequency Oscillations of Plasma Injected in Open Magnetic Trap from Independent Ultra-high Frequency Source
Creators: name: Nanobashvili, S. I.
name: Beria, Z. R.
name: Gelashvili, G. V.
name: Gogiashvili, G. E.
name: Nanobashvili, I. S.
name: Tavkhelidze, G. P.
name: Van Oost, G
Publisher: name: arXiv
Year: 2022
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Methods of plasma heating by electromagnetic waves, interaction of electro-magnetic waves with magnetoactive plasma, plasma turbulence and transport processes are investigated in the trap of the linear plasma device OMT2. An ultrahigh frequency (UHF) contactless method is used to fill the open magnetic trap by plasma. We propose a new method of open magnetic trap filling with plasma whereby plasma is injected in the trap along the magnetic field from an independent stationary UHF source. The source is located outside the trap and plasma formation in it takes place in the strongly nonuniform magnetic field, in the electron cyclotron resonance (ECR) regime by means of the UHF power. In this paper we study the efficiency of open magnetic trap filling by plasma and plasma low frequency (LF) oscillations in the trap.
Deviation of Mercury's spin axis from an exact Cassini state induced by dissipation
Creators: name: MacPherson, Ian
name: Dumberry, Mathieu
Publisher: name: arXiv
Year: 2022
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: We compute predictions of the deviation of Mercury's spin axis from an exact Cassini state caused by tidal dissipation, and viscous and electromagnetic (EM) friction at the core-mantle boundary (CMB) and inner core boundary (ICB). Viscous friction at the CMB generates a phase lead, viscous and EM friction at the ICB produce a phase lag; the magnitude of the deviation depends on the inner core size, kinematic viscosity and magnetic field strength, but cannot exceed an upper bound. For a small inner core, viscous friction at the CMB results in a maximum phase lead of 0.027 arcsec. For a large inner core (radius $>1000$ km), EM friction at the ICB generates the largest phase lag, but it does not exceed 0.1 arcsec. Elastic deformations induced by the misaligned fluid and solid cores play a first order role in the phase lead/lag caused by viscous and EM coupling, and contribute to a perturbation in mantle obliquity on par with that caused by tidal deformations. Tidal dissipation results in a phase lag and its magnitude (in units of arcsec) is given by the empirical relation (80/Q), where Q is the quality factor; Q=80 results in a phase lag of ~1 arcsec. A large inner core with a low viscosity of the order of 10^{17} Pa s or lower can significantly affect $Q$ and thus the resulting phase lag. The limited mantle phase lag suggested by observations (<10 arcsec) implies a lower limit on the bulk mantle viscosity of approximately 10^{17} Pa s.
description: 40 pages, 11 figures
Mating competition among females: testing the distinction between natural and sexual selection in an insect â€“ supplementary materials
Creators: name: PÃ¤rssinen, Varpu
name: Simmons, Leigh William
name: Kvarnemo, Charlotta
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310499
subject: Evolutionary biology not elsewhere classified

description: Table S1 and Figure S1
Characterizing the Reproducibility of Noisy Quantum Circuits
Creators: name: Dasgupta, Samudra
name: Humble, Travis S.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The ability of a quantum computer to reproduce or replicate the results of a quantum circuit is a key concern for verifying and validating applications of quantum computing. Statistical variations in circuit outcomes that arise from ill-characterized fluctuations in device noise may lead to computational errors and irreproducible results. While device characterization offers a direct assessment of noise, an outstanding concern is how such metrics bound the reproducibility of a given quantum circuit. Here, we first directly assess the reproducibility of a noisy quantum circuit, in terms of the Hellinger distance between the computational results, and then we show that device characterization offers an analytic bound on the observed variability. We validate the method using an ensemble of single qubit test circuits, executed on a superconducting transmon processor with well-characterized readout and gate error rates. The resulting description for circuit reproducibility, in terms of a composite device parameter, is confirmed to define an upper bound on the observed Hellinger distance, across the variable test circuits. This predictive correlation between circuit outcomes and device characterization offers an efficient method for assessing the reproducibility of noisy quantum circuits.
description: Published in the journal Entropy, 2022, 24, 244 (https://doi.org/10.3390/e24020244)
Impact of renal function on ischemic stroke and major bleeding rates in nonvalvular atrial fibrillation patients treated with warfarin or rivaroxaban: a retrospective cohort study using real-world evidence
Creators: name: Weir, Matthew R.
name: Berger, Jeffrey S.
name: Ashton, Veronica
name: Laliberté, François
name: Brown, Kip
name: Lefebvre, Patrick
name: Schein, Jeffrey
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: Hematology

description: Objectives: Renal dysfunction is associated with increased risk of cardiovascular disease and is an independent predictor of stroke and systemic embolism. Nonvalvular atrial fibrillation (NVAF) patients with renal dysfunction may face a particularly high risk of thromboembolism and bleeding. The current retrospective cohort study was designed to assess the impact of renal function on ischemic stroke and major bleeding rates in NVAF patients in the real-world setting (outside a clinical trial). Methods: Medical claims and Electronic Health Records were retrieved retrospectively from Optum’s Integrated Claims–Clinical de-identified dataset from May 2011 to August 2014. Patients with NVAF treated with warfarin (2468) or rivaroxaban (1290) were selected. Each treatment cohort was stratified by baseline estimated creatinine clearance (eCrCl) levels. Confounding adjustments were made using inverse probability of treatment weights (IPTWs). Incidence rates and hazard ratios of ischemic stroke and major bleeding events were calculated for both cohorts. Results: Overall, patients treated with rivaroxaban had an ischemic stroke incidence rate of 1.9 per 100 person-years (PY) while patients treated with warfarin had a rate of 4.2 per 100 PY (HR = 0.41 [0.21–0.80], p = .009). Rivaroxaban patients with an eCrCl below 50 mL/min (N = 229) had an ischemic stroke rate of 0.8 per 100 PY, while the rate for the warfarin cohort (N = 647) was 6.0 per 100 PY (HR = 0.09 [0.01–0.72], p = .02). For the other renal function levels (i.e. eCrCl 50–80 and ≥80 mL/min) HRs indicated no statistically significant differences in ischemic stroke risks. Bleeding events did not differ significantly between cohorts stratified by renal function. Conclusions: Ischemic stroke rates were significantly lower in the overall NVAF population for rivaroxaban vs. warfarin users, including patients with eCrCl below 50 mL/min. For all renal function groups, major bleeding risks were not statistically different between treatment groups.
Additional file 5: of New insights into the evolution and functional divergence of the SWEET family in Saccharum based on comparative genomics
Creators: name: Hu, Weichang
name: Hua, Xiuting
name: Zhang, Qing
name: Wang, Jianping
name: Shen, Qiaochu
name: Zhang, Xingtan
name: Wang, Kai
name: Yu, Qingyi
name: Lin, Yann-Rong
name: Ming, Ray
name: Zhang, Jisen
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Plant Biology

description: A RT-qPCR verification of SWEET2b and SWEET4b in partial tissues of two Saccharum species. Note: IN, internode; LR, leaf roll. Internodes 3, 9, 15 and internodes 3, 6, 9 were from S. officinarum LA-Purple and S. spontaneum SES-208, respectively. B Correlation coefficient between RNA-seq (X axis) and RT-qPCR (Y axis) of two SsSWEET genes (SsSWEET2b and SsSWEET4b). (PDF 47 kb)
Проблеми, перспективи та програма вивчення мінерально - сировинного видобувничо - переробного комплексу Давньої Русі - України.
Creators: name: Томашевський, Андрій
Publisher: name: figshare
Year: 2017
Subjects: History

description: Проблеми, перспективи та програма вивчення мінерально - сировинного видобувничо - переробного комплексу Давньої Русі - України. // Матеріали першої міжнародної конференції “Коштовне і декоративне каміння”, К., 1999, с. 92-93.
Перші попередні підсумки дослідження овруцького пірофілітового промислу Х-ХІІІ ст.
Creators: name: Томашевський, Андрій
name: Павленко С.В.
Publisher: name: figshare
Year: 2017
Subjects: Archaeology

description: Томашевський А.П., Павленко С.В. Перші попередні підсумки дослідження овруцького пірофілітового промислу Х-ХІІІ ст. // Бюлетень першої міжнародної конференції “Коштовне та декоративне каміння”. – К., 1999. – С. 92-93.
Ownership Structure, Board Characteristics and Intellectual Capital Performance of Firms in Malaysia
Creators: name: Ismail, Ku Nor Izah Ku
name: Robiah
name: Musalli, Al
Publisher: name: figshare
Year: 2017
Subjects: subject: 150103 Financial Accounting
subject: FOS: Economics and business

description: This paper appeared in Advanced Science Letters (Volume 22, 2016). It examines intellectual capital (IC) performance of large Malaysian listed companies and observes if ownership structure and board characteristics are associated with IC performance. The study focuses on 58 firm’s IC performance for the period 2006 and 2011, giving a total of 116 observations. Controlling for board size, firm performance and industry, the findings show that government-owned companies have lower IC performance compared to nongovernment-owned companies. IC performance is also lower for companies whose Chairman and CEO are of the same person, compared to companies that separate the two roles. There is also evidence that corporate governance and ownership structure play a vital role in influencing IC performance among firms in Malaysia. This study offers insights to the regulators in making new or improving existing policies. Since corporate governance attributes influence IC investments, findings of this study could benefit policy makers in deliberating issues and policies related to corporate governance, which will in turn determine the direction of firms’ future governance policies. Authorities who are responsible for the betterment of business environment in Malaysia may make changes to the existing policies to promote the development of IC and increase investment planning policy at the corporate level. Investors seeking to invest in Malaysian companies can utilize the findings of this study in determining features that may provide an indication of future IC performance.
MOESM1 of Dysfunctional epigenetic aging of the normal colon and colorectal cancer risk
Creators: name: Wang, Ting
name: Maden, Sean
name: Luebeck, Georg
name: Li, Christopher
name: Newcomb, Polly
name: Ulrich, Cornelia
name: Joo, Ji-Hoon
name: Buchanan, Daniel
name: Milne, Roger
name: Southey, Melissa
name: Carter, Kelly
name: Willbanks, Amber
name: Luo, Yanxin
name: Yu, Ming
name: Grady, William
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Mental Health

description: Figure S1. Distributions of gender, age, batch and CRC risk of the studied samples. Figure S2. Distributions of gender and age in three CRC risk groups in the EPIC and HM450 array datasets. Figure S3. Venn diagrams of epigenetic clock CpGs on the HM450 and EPIC methylation arrays. Figure S4. Distribution of epigenetic age in three CRC risk groups. Figure S5. Association of the estimated cell-type fractions with DNAm data, individual CRC risk and chronological/epigenetic ages. Figure S6. Distribution of epigenetic age acceleration in three CRC risk groups, with the adjustment for gender, cell-type fractions, BMI, smoking and NSAID use of subjects. Figure S7. Replication results of comparing epigenetic age acceleration between the low and high risk normal colons using two validation datasets. Figure S8. Analysis of the combined dataset of normal colon and CRC samples. Figure S9. EWAS results of CRC risk. Figure S10. Association of DNAm GrimAge in the normal colon with individual chronological age and CRC risk. Figure S11. Sensitivity analysis of the HM450 array dataset using the common clock CpGs on both HM450 and EPIC arrays. Figure S12. Epigenetic age estimates of the samples in the HM450 array dataset. Figure S13. Epigenetic age estimates of the samples in the EPIC array dataset.
Circular RNA circ_0002360 regulates the Taxol resistance and malignant behaviors of Taxol-resistant non-small cell lung cancer cells by microRNA-585-3p-dependent modulation of G protein regulated inducer of neurite outgrowth 1
Creators: name: Cui, Xiaohai
name: Zhang, Boxiang
name: Li, Baocheng
name: Li, Xinju
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Developmental Biology
subject: Cancer
subject: Statistics
subject: FOS: Mathematics
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: Drug resistance has become the major obstacle for the treatment of non-small cell lung cancer (NSCLC). Circular RNAs (circRNAs) are tightly linked to the development of drug resistance of NSCLC. Herein, we tested the function of circ_0002360 in the Taxol resistance of NSCLC. Circ_0002360, microRNA (miR)-585-3p and G protein regulated inducer of neurite outgrowth 1 (GPRIN1) were quantified by quantitative real-time PCR (qRT-PCR). To identify the circular structure of circ_0002360, RNase R digestion was applied. To detect cell proliferation, colony formation and 5-ethynyl-2’-deoxyuridine (EdU) assays were used. For assessment of cell apoptosis, flow cytometry was adopted. For motility and invasion analyses, transwell assay was employed. Our data showed that circ_0002360 was mainly located in the cytoplasm and was highly expressed in the Taxol-resistant NSCLC. Silencing of circ_0002360 inhibited cell Taxol resistance, proliferation, motility, and invasiveness and induced apoptosis in vitro. MiR-585-3p was underexpressed in Taxol-resistant NSCLC and was targeted by circ_0002360. MiR-585-3p knockdown alleviated the influence of circ_0002360 silence on Taxol-resistant cells. GPRIN1 was directly targeted by miR-585-3p. The influence of miR-585-3p on cell Taxol resistance and functional behaviors was reversed by GPRIN1 overexpression. Moreover, circ_0002360 modulated GPRIN1 through miR-585-3p. Additionally, silencing of circ_0002360 weakened the growth of xenografts in vivo. Our study demonstrated that silencing of circ_0002360 enhanced the Taxol sensitivity and suppressed the malignant behaviors of Taxol-resistant NSCLC cells by miR-585-3p/GPRIN1 axis, providing novel targets for improving the anti-tumor efficacy of Taxol in NSCLC.
Statistic script
Creators: name: Berthet, Mélissa
Publisher: name: figshare
Year: 2018
Subjects: subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: R script used in the article.

We found a small mistake in the original script and thus corrected and updated the script on the 2018.02.16
Овруцький кряж: комплексне вивчення та збереження історико-археологічної і палеоприродної спадщини (Завдання, перспективи, структура проекту)
Creators: name: Томашевський, Андрій
Publisher: name: figshare
Year: 2017
Subjects: subject: History
subject: Archaeology
subject: 60206 Palaeoecology
subject: FOS: Biological sciences

description: Овруцький кряж: комплексне вивчення та збереження історико-археологічної і палеоприродної спадщини (Завдання, перспективи, структура проекту) // Археологія. - №2, 1998 – С. 151-155
Перспективи та проблеми комплексного вивчення i збереження історико - культурної та палеоприродної спадщини на зламі тисячоліть.
Creators: name: Томашевський, Андрій
Publisher: name: figshare
Year: 2017
Subjects: Archaeology

description: Перспективи та проблеми комплексного вивчення i збереження історико - культурної та палеоприродної спадщини на зламі тисячоліть. // Матеріали конференції “Людина в ландшафті ХХІ століття”. - К., 1998., С.130 - 135
Попередні підсумки археологічних досліджень Овруцької археологічної експедиції у 1996 - 1997 роках на території Овруцького району Житомирської області
Creators: name: Томашевський, Андрій
Publisher: name: figshare
Year: 2017
Subjects: Archaeology

description: Попередні підсумки археологічних досліджень Овруцької археологічної експедиції у 1996 - 1997 роках на території Овруцького району Житомирської області // зб. Археологічні відкриття в Україні 1997-1998 рр. - К., 1998, с.45 - 48
The Prospects of Finding Tidal Disruption Events with 2.5-Metre Wide-Field Survey Telescope (WFST) Based on Mock Observations
Creators: name: Lin, Zheyu
name: Jiang, Ning
name: Kong, Xu
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Optical time-domain survey has been the dominant means of hunting for rare tidal disruption events (TDEs) in the past decade and remarkably advanced the TDE study. Particularly, the Zwicky Transient Facility (ZTF) has opened the era of population studies and the upcoming Large Synoptic Survey Telescope (LSST) at the Vera Rubin Observatory (VRO) is believed to further revolutionize the field soon. Here we present the prospects of finding TDEs with another powerful survey to be performed by 2.5-metre Wide-Field Survey Telescope (WFST). The WFST, located in western China, will be the most advanced facility dedicated to optical time-domain surveys in the northern hemisphere once commissioning. We choose to assess its TDE detectability on the basis of mock observations, which is hitherto closest to reality by taking into consideration of site conditions, telescope parameters, survey strategy and transient searching pipeline. Our mock observations on 440 deg$^2$ field (CosmoDC2 catalogue) show that $29\pm6$ TDEs can be robustly found per year if observed at $u, g, r, i$ bands with 30-second exposure every 10 days, in which a discovery is defined as $\geq$10 epochal detections in at least two filters. If the WFST survey is fully optimized for discovering TDE, we would expect to identify $392\pm74$ of TDEs every year, with the redshift up to $z\sim0.8$, which poses a huge challenge to follow-up resources.
description: 16 pages, 8 figures, 4 tables, accepted for publication in MNRAS
Additional file 6: of New insights into the evolution and functional divergence of the SWEET family in Saccharum based on comparative genomics
Creators: name: Hu, Weichang
name: Hua, Xiuting
name: Zhang, Qing
name: Wang, Jianping
name: Shen, Qiaochu
name: Zhang, Xingtan
name: Wang, Kai
name: Yu, Qingyi
name: Lin, Yann-Rong
name: Ming, Ray
name: Zhang, Jisen
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: PCR verification of SWEET4e and SWEET16b in two Saccharum species. (PDF 53 kb)
Перспективи та проблеми комплексного вивчення та збереження історико - культурної та палеоприродної спадщини на зламі тисячоліть.
Creators: name: Томашевський, Андрій
Publisher: name: figshare
Year: 2017
Subjects: Archaeology

description: Перспективи та проблеми комплексного вивчення та збереження історико - культурної та палеоприродної спадщини на зламі тисячоліть. // Матеріали конференції “Людина в ландшафті ХХІ століття”. - К., 1998., С.130 - 135
Stuttgart Open Relay Degradation Dataset (SOReDD)
Creators: name: Maschler, Benjamin
name: Iliev, Angel
name: Pham, Thi Thu Huong
name: Weyrich, Michael
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Real-life industrial use cases for machine learning oftentimes involve heterogeneous and dynamic assets, processes and data, resulting in a need to continuously adapt the learning algorithm accordingly. Industrial transfer learning offers to lower the effort of such adaptation by allowing the utilization of previously acquired knowledge in solving new (variants of) tasks. Being data-driven methods, the development of industrial transfer learning algorithms naturally requires appropriate datasets for training. However, open-source datasets suitable for transfer learning training, i.e. spanning different assets, processes and data (variants), are rare. With the Stuttgart Open Relay Degradation Dataset (SOReDD) we want to offer such a dataset. It provides data on the degradation of different electromechanical relays under different operating conditions, allowing for a large number of different transfer scenarios. Although such relays themselves are usually inexpensive standard components, their failure often leads to the failure of a machine as a whole due to their role as the central power switching element of a machine. The main cost factor in the event of a relay defect is therefore not the relay itself, but the reduced machine availability. It is therefore desirable to predict relay degradation as accurately as possible for specific applications in order to be able to replace relays in good time and avoid unplanned machine downtimes. Nevertheless, data-driven failure prediction for electromechanical relays faces the challenge that relay degradation behavior is highly dependent on the operating conditions, high-resolution measurement data on relay degradation behavior is only collected in rare cases, and such data can then only cover a fraction of the possible operating environments. Relays are thus representative of many other central standard components in automation technology.
description: Dataset description (8 pages, 4 figures, 8 tables)
Evolving Neural Selection with Adaptive Regularization
Creators: name: Ding, Li
name: Spector, Lee
Publisher: name: arXiv
Year: 2022
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Over-parameterization is one of the inherent characteristics of modern deep neural networks, which can often be overcome by leveraging regularization methods, such as Dropout. Usually, these methods are applied globally and all the input cases are treated equally. However, given the natural variation of the input space for real-world tasks such as image recognition and natural language understanding, it is unlikely that a fixed regularization pattern will have the same effectiveness for all the input cases. In this work, we demonstrate a method in which the selection of neurons in deep neural networks evolves, adapting to the difficulty of prediction. We propose the Adaptive Neural Selection (ANS) framework, which evolves to weigh neurons in a layer to form network variants that are suitable to handle different input cases. Experimental results show that the proposed method can significantly improve the performance of commonly-used neural network architectures on standard image recognition benchmarks. Ablation studies also validate the effectiveness and contribution of each component in the proposed framework.
Complementary details for the manuscript and additional constitutive formulations from Mathematical and computational modelling of skin biophysics: a review
Creators: name: Limbert, Georges
Publisher: name: The Royal Society
Year: 2017
Subjects: Biophysics
Mechanics
Computational Biology

description: The objective of this paper is to provide a review on some aspects of the mathematical and computational modelling of skin biophysics, with special focus on constitutive theories based on nonlinear continuum mechanics from elasticity, through anelasticity, including growth, to thermoelasticity. Microstructural and phenomenological approaches combining imaging techniques are also discussed. Finally, recent research applications on skin wrinkles will be presented to highlight the potential of physics-based modelling of skin in tackling global challenges such as ageing of the population and the associated skin degradation, diseases and traumas.
Supplementary Table 1 from Co-option of a motor-to-sensory histaminergic circuit correlates with insect flight biomechanics
Creators: name: Chapman, Phillip D.
name: Samual P. Bradley
name: Haught, Erica J.
name: Riggs, Kassandra E.
name: Mouaz M. Haffar
name: Daly, Kevin C.
name: Dacks, Andrew M.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences

description: Supplementary Table 1: Taxonomic classification of species examined including flight behavior, wingbeat frequency, sample sizes (n) used in this study, and presence of MDH neuron innervation in the AL. All specimens were identified to species with the exception of the caddisfly which could only be keyed down to family.
T*$\varepsilon$ -- Bounded-Suboptimal Efficient Motion Planning for Minimum-Time Planar Curvature-Constrained Systems
Creators: name: Pinsky, Doron
name: Váňa, Petr
name: Faigl, Jan
name: Salzman, Oren
Publisher: name: arXiv
Year: 2022
Subjects: subject: Robotics (cs.RO)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: We consider the problem of finding collision-free paths for curvature-constrained systems in the presence of obstacles while minimizing execution time. Specifically, we focus on the setting where a planar system can travel at some range of speeds with unbounded acceleration. This setting can model many systems, such as fixed-wing drones. Unfortunately, planning for such systems might require evaluating many (local) time-optimal transitions connecting two close-by configurations, which is computationally expensive. Existing methods either pre-compute all such transitions in a preprocessing stage or use heuristics to speed up the search, thus foregoing any guarantees on solution quality. Our key insight is that computing all the time-optimal transitions is both~(i)~computationally expensive and~(ii)~unnecessary for many problem instances. We show that by finding bounded-suboptimal solutions (solutions whose cost is bounded by $1+\varepsilon$ times the cost of the optimal solution for any user-provided $\varepsilon$) and not time-optimal solutions, one can dramatically reduce the number of time-optimal transitions used. We demonstrate using empirical evaluation that our planning framework can reduce the runtime by several orders of magnitude compared to the state-of-the-art while still providing guarantees on the quality of the solution.
description: 8 pages, 6 figures
Additional file 12 of Global transcriptional profiling between inbred parents and hybrids provides comprehensive insights into ear-length heterosis of maize (Zea mays)
Creators: name: Zhang, Xiangge
name: Ma, Chenchen
name: Wang, Xiaoqing
name: Wu, Mingbo
name: Shao, Jingkuan
name: Huang, Li
name: Yuan, Liang
name: Fu, Zhiyuan
name: Li, Weihua
name: Zhang, Xuehai
name: Guo, Zhanyong
name: Tang, Jihua
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 12: Table S8. The sequence of primers used for qRT-PCR
Template-free synthesis of mesoporous α-Fe2O3 nanoflowers with short charge-carrier diffuse distance for superior photocatalysis
Creators: name: Q. Du
name: Q. Gao
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences

description: In this work, well-shaped monodisperse mesoporous α-Fe2O3 nanoflowers were prepared by a facile template-free solvothermal route. The α-Fe2O3 nanoflowers with size of ~80 nm composed of nanobranches with width of ~10 nm. Contributed by the short charge-carrier diffuse distance of thin branches, the as-prepared mesoporous α-Fe2O3 nanoflowers possess notably higher phtotocatalytic activity in comparison with non-porous samples, commercial α-Fe2O3 and TiO2 by a model organic dye degradation reaction of Rhodamine B. The kinetic constant of mesoporous α-Fe2O3 nanoflowers for Rhodamine B degradation is about twice that of the non-porous materials and 10 times that of commercial α-Fe2O3 photocatalyst. Therefore, a simple method is developed to access the highly active mesoporous α-Fe2O3 nanoflowers, and the as-prepared material is potential to be used in photocatalysis or solar energy harvest.
Double Schubert polynomials for the classical groups
Creators: name: Ikeda, Takeshi
name: Mihalcea, Leonardo C.
name: Naruse, Hiroshi
Publisher: name: arXiv
Year: 2008
Subjects: subject: Combinatorics (math.CO)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 05E15 (Primary), 14N15, 14M15, 05E05 (Secondary)

description: For each infinite series of the classical Lie groups of type B,C or D, we introduce a family of polynomials parametrized by the elements of the corresponding Weyl group of infinite rank. These polynomials represent the Schubert classes in the equivariant cohomology of the appropriate flag variety. They satisfy a stability property, and are a natural extension of the (single) Schubert polynomials of Billey and Haiman, which represent non-equivariant Schubert classes. They are also positive in a certain sense, and when indexed by maximal Grassmannian elements, or by the longest element in a finite Weyl group, these polynomials can be expressed in terms of the factorial analogues of Schur's Q- or P-functions defined earlier by Ivanov.
description: 41 pages, 2 tables; comments welcome
Generalized (co)homology of the loop spaces of classical groups and the universal factorial Schur $P$- and $Q$-functions
Creators: name: Nakagawa, Masaki
name: Naruse, Hiroshi
Publisher: name: arXiv
Year: 2013
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 05E05, 55N20, 57T25

description: In this paper, we study the generalized (co)homology Hopf algebras of the loop spaces on the infinite classical groups, generalizing the work due to Kono-Kozima and Clarke. We shall give a description of these Hopf algebras in terms of symmetric functions. Based on topological considerations in the first half of this paper, we then introduce a universal analogue of the factorial Schur $P$- and $Q$-functions due to Ivanov and Ikeda-Naruse. We investigate various properties of these functions such as the cancellation property, which we call the $\mathbb{L}$-supersymmetric property, the factorization property, and the vanishing property. We prove that the universal analogue of the Schur $P$-functions form a formal basis for the ring of functions with the $\mathbb{L}$-supersymmetric property. By using the universal analogue of the Cauchy identity, we then define the dual universal Schur $P$- and $Q$-functions. We describe the duality of these functions in terms of Hopf algebras.
description: 47 pages, typos corrected, exposition improved
Factorial P- and Q-Schur functions represent equivariant quantum Schubert classes
Creators: name: Ikeda, Takeshi
name: Mihalcea, Leonardo C.
name: Naruse, Hiroshi
Publisher: name: arXiv
Year: 2014
Subjects: subject: Combinatorics (math.CO)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14M15, 53D45

description: We find presentations by generators and relations for the equivariant quantum cohomology rings of the maximal isotropic Grassmannians of types B,C and D, and we find polynomial representatives for the Schubert classes in these rings. These representatives are given in terms of the same Pfaffian formulas which appear in the theory of factorial $P$- and $Q$-Schur functions. After specializing to equivariant cohomology, we interpret the resulting presentations and Pfaffian formulas in terms of Chern classes of tautological bundles.
description: 24 pages; comments welcome!