cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On accelerated alternating minimization
Creators: name: Guminov, Sergey
name: Dvurechensky, Pavel
name: Gasnikov, Alexander
Publisher: name: Weierstrass Institute
Year: 2020
Subjects: subject: Convex optimization
subject: acceleration
subject: non-convex optimization
subject: alternating minimization
subject: 90C30
subject: 90C25
subject: 68Q25

description: Alternating minimization (AM) optimization algorithms have been known for a long time and are of importance in machine learning problems, among which we are mostly motivated by approximating optimal transport distances. AM algorithms assume that the decision variable is divided into several blocks and minimization in each block can be done explicitly or cheaply with high accuracy. The ubiquitous Sinkhorn's algorithm can be seen as an alternating minimization algorithm for the dual to the entropy-regularized optimal transport problem. We introduce an accelerated alternating minimization method with a $1/k^2$ convergence rate, where $k$ is the iteration counter. This improves over known bound $1/k$ for general AM methods and for the Sinkhorn's algorithm. Moreover, our algorithm converges faster than gradient-type methods in practice as it is free of the choice of the step-size and is adaptive to the local smoothness of the problem. We show that the proposed method is primal-dual, meaning that if we apply it to a dual problem, we can reconstruct the solution of the primal problem with the same convergence rate. We apply our method to the entropy regularized optimal transport problem and show experimentally, that it outperforms Sinkhorn's algorithm.
The REVAMP trial to evaluate HIV resistance testing in sub-Saharan Africa: a case study in clinical trial design in resource limited settings to optimize effectiveness and cost effectiveness estimates
Creators: name: Siedner, Mark J.
name: Mwebesa B. Bwana
name: Mahomed-Yunus S. Moosa
name: Paul, Michelle
name: Selvan Pillay
name: McCluskey, Suzanne
name: Aturinda, Isaac
name: Ard, Kevin
name: Muyindike, Winnie
name: Pravikrishnen Moodley
name: Jaysingh Brijkumar
name: Tamlyn Rautenberg
name: George, Gavin
name: Johnson, Brent
name: Gandhi, Rajesh T.
name: Sunpath, Henry
name: Marconi, Vincent C.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences

description: Background: In sub-Saharan Africa, rates of sustained HIV virologic suppression remain below international goals. HIV resistance testing, while common in resource-rich settings, has not gained traction due to concerns about cost and sustainability. Objective: We designed a randomized clinical trial to determine the feasibility, effectiveness, and cost-effectiveness of routine HIV resistance testing in sub-Saharan Africa. Approach: We describe challenges common to intervention studies in resource-limited settings, and strategies used to address them, including: (1) optimizing generalizability and cost-effectiveness estimates to promote transition from study results to policy; (2) minimizing bias due to patient attrition; and (3) addressing ethical issues related to enrollment of pregnant women. Methods: The study randomizes people in Uganda and South Africa with virologic failure on first-line therapy to standard of care virologic monitoring or immediate resistance testing. To strengthen external validity, study procedures are conducted within publicly supported laboratory and clinical facilities using local staff. To optimize cost estimates, we collect primary data on quality of life and medical resource utilization. To minimize losses from observation, we collect locally relevant contact information, including Whatsapp account details, for field-based tracking of missing participants. Finally, pregnant women are followed with an adapted protocol which includes an increased visit frequency to minimize risk to them and their fetuses. Conclusions: REVAMP is a pragammatic randomized clinical trial designed to test the effectiveness and cost-effectiveness of HIV resistance testing versus standard of care in sub-Saharan Africa. We anticipate the results will directly inform HIV policy in sub-Saharan Africa to optimize care for HIV-infected patients.
Enhanced anti-hepatocarcinoma efficacy by GLUT1 targeting and cellular microenvironment-responsive PAMAM–camptothecin conjugate
Creators: name: Ma, Pengkai
name: Sun, Yi
name: Chen, Jianhua
name: Li, Hongpin
name: Zhu, Hongyu
name: Gao, Xing
name: Bi, Xinning
name: Zhang, Yujie
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: The efficient targeting of drugs to tumor cell and subsequent rapid drug release remain primary challenges in the development of nanomedicines for cancer therapy. Here, we constructed a glucose transporter 1 (GLUT1)-targeting and tumor cell microenvironment-sensitive drug release Glucose–PEG–PAMAM-s-s–Camptothecin-Cy7 (GPCC) conjugate to tackle the dilemma. The conjugate was characterized by a small particle size, spherical shape, and glutathione (GSH)-sensitive drug release. In vitro tumor targeting was explored in monolayer (2D) and multilayer tumor spheroid (3D) HepG2 cancer cell models (GLUT1+). The cellular uptake of GPCC was higher than that in the control groups and that in normal L02 cells (GLUT1−), likely due to the conjugated glucose moiety. Moreover, the GPCC conjugate exhibited stronger cytotoxicity, higher S arrest and enhanced apoptosis and necrosis rate in HepG2 cells than control groups but not L02 cells. However, the cytotoxicity of GPCC was lower than that of free CPT, which could be explained by the slower release of CPT from the GPCC compared with free CPT. Additional in vivo tumor targeting experiments demonstrated the superior tumor-targeting ability of the GPCC conjugate, which significantly accumulated in tumor meanwhile minimize in normal tissues compared with control groups. The GPCC conjugate showed better pharmacokinetic properties, enabling a prolonged circulation time and increased camptothecin area under the curve (AUC). These features contributed to better therapeutic efficacy and lower toxicity in H22 hepatocarcinoma tumor-bearing mice. The GLUT1-targeting, GSH-sensitive GPCC conjugate provides an efficient, safe and economic approach for tumor cell targeted drug delivery.
Spanish (Mexico) TCoA-IIIA
Creators: name: Brown, Gavin
Publisher: name: The University of Auckland
Year: 2017
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology
subject: Education

description: This translation was created by Elizabeth Ruiz Esparza Barajas, University of Sonora, Mexico while she was PhD candidate at Macquarie University, Sydney, Australia, April 2007. Email: lizabeth_ruiz@yahoo.com Publications arising from this study includeRuiz-Esparza, E. (2009). The role of beliefs about assessment in a Bachelor in English Language Teaching program in Mexico. (Unpublished doctoral dissertaton), Macquarie University, Sydney, NSW. Ruiz-Esparza, E. (2012). University teachers' beliefs about purposes of assessment. In M. C. Contijoch & K. B. Lusnia (Eds.), Investigación y enseñanza de lenguas: andanzas y reflexiones (pp. (pp. 201-215). Mexico, D.F.: Universidad Nacional Autónoma de México.  
Spanish (Spain) TCoA-IIIA
Creators: name: Brown, Gavin
name: Remesal, Ana
Publisher: name: The University of Auckland
Year: 2017
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology
subject: Education

description: This translation was created by Ana Remesal, PhD., Department of Developmental and Educational Psychology, University of Barcelona, Spain. This translation has been done with special care to avoid technical jargon, so as to be responded by teacher-students. The language follows the Peninsular-Spanish standards. Email: aremesal@ub.edu Recommended citation for this version. Remesal, A. (2009). Cuestionario Abreviado de Concepciones de Evaluación del Aprendizaje. Unpublished translation of Teachers' Conceptions of Assessment inventory (CoA-IIIA), Universidad de Barcelona, Spain.This version was used in the following publication: Brown, G. T. L., & Remesal, A. (2012). Prospective teachers’ conceptions of assessment: A cross-cultural comparison. The Spanish Journal of Psychology, 15(1), 75-89. doi: 10.5209/rev_SJOP.2012.v15.n1.37286
Mustang advertising and the impact of feminism: women’s representation in ads from 1964-1975
Creators: name: Powell, Marissa
Publisher: name: No Publisher Supplied
Year: 2022

description: This thesis, Mustang Advertising and the Impact of Feminism: Women’s Representation in Ads from 1964-1975 examines the change of women’s representation in Mustang advertising from 1964-1975. Despite the Mustang’s overall success, Ford would fail to properly embrace Feminist theory and concepts during the late 1960s and early 1970s. The following research analyzes a variety of advertising to show that, by attempting to utilize feminism within advertisements, Ford’s use of a feminist inspired “independent woman” would still rely on gender roles. This thesis topic gives the opportunity to reflect on the history of women’s representation in advertising and how women are represented in advertising today. Utilizing a combination of primary documents collected from sources such as The Henry Ford Archive; and a variety of secondary sources covering the topics of advertising, automobile history, and feminist history, these topics combined support my analysis of 1964-1975 Mustang advertising. Mustang advertisements from 1965 would heavily rely on glamourized and gendered depictions of women to promote their products. This glamourization would soon give way to depictions of an “independent woman” inspired by second wave-feminists starting in 1966. This depiction however would ultimately fall flat, due to reliance on gender roles created in a post war era. Concluding the research by examining the impact of the rising environmental crisis in the 1970’s, Ford’s attempts of addressing rising social issues can be seen implemented in a similar fashion to it’s attempts at addressing feminist audiences. It’s success at addressing environmental concerns much like it’s attempts at acknowledging feminism would be unsuccessful. With the next generation of Mustang’s introduced to a unimpressed public, Ford would once again enter into a period of uncertainty where innovation was called upon once again. Using these findings to better understand the history of women’s representation in advertising, similar observations can be made about modern advertising and how it impacts women today.
Index to Some Sources of Current Prices
Creators: name: Shively, Eva Thayer
name: Shively, Eva Thayer
Publisher: name: Unknown
Year: 1923
Subjects: subject: Demand and Price Analysis
subject: Marketing
subject: FOS: Economics and business

description: Excerpts from the Introduction: This list of the sources of current prices was compiled to meet an urgent need in the library of the Bureau of Agricultural Economics, U. S. Department of Agriculture. No claim is made for completeness. We hope to add to the number of periodicals indexed as soon as practicable. In spite of the incompleteness of the list, our need for it made us decide not to delay its publication. In most cases we have used the terminology found in the periodicals themselves. Cities or commodities quoted infrequently have not been mentioned. The items starred are those which do not appear regularly but do appear with enough frequency to be useful.
AN EMPIRICAL STUDY OF IMPACT OF SIZE OF FIRM ON LEVERAGE
Creators: name: Dr. MOHAMMAD ATHAR ALI
Publisher: name: Zenodo
Year: 2024
Subjects: Leverage, Business Size, India, Pecking Order Theory, Financing Behaviour.

description: Abstract

The purpose of this study is to look into the relationship between leverage and firm size in the business environment of India, a major growing country. Prior research studies have mostly surveyed developed countries; however, our analysis fills this vacuum by examining a sizable sample of companies throughout a 20-year span, from 2002 to 2021. Our data show a negative link between size and leverage, supporting the pecking order theory's claims. This implies that businesses tend to rely less on debt as they get bigger. Policymakers should take note of these findings, especially in light of how India's corporate loan market is developing. Policymakers can create an environment that is favorable by recognizing and comprehending the complexities of the size-leverage relationship and using this knowledge to inform their decisions.
Turbulent flow of Generalised Newtonian fluids through pipes and open channels
Creators: name: JAGMOHAN SINGH
Publisher: name: Monash University
Year: 2017
Subjects: subject: 91508 Turbulent Flows
subject: FOS: Other engineering and technologies
subject: 80110 Simulation and Modelling
subject: FOS: Computer and information sciences

description: Many fluids in industries and in nature show generalised Newtonian (GN) behaviour, i.e. they show a shear dependent viscosity. Fine particle suspensions found in mining and waste water industries are common examples of GN fluids. Pipes and open channels are two common mediums of transporting these fluids at industrial sites. The current thesis investigates the flow of GN fluids through pipes and open channels using a numerical technique called direct numerical simulations (DNS) to highlight the differences brought by the GN rheology compared to Newtonian fluids. The current work will give a direction to the development of computationally less expensive numerical techniques such as Reynolds-averaged Navier-Stokes simulations and large-eddy simulations for GN fluids. The work will also be helpful in improving the existing methods of designing fluid systems for GN fluids.
MPEC 2024-G167 : 2024 GA4
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 GA4

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Uso de redes sociales académicas por investigadores de Sociología en México
Creators: name: Vilchis, Ivonne Lujano
Publisher: name: figshare
Year: 2017
Subjects: subject: Sociology
subject: FOS: Sociology

description: Analysis of the use of academic social networks by researchers in the area of Sociology of the National System of Researchers (SNI) in Mexico.
*Paper presented at the 4th Latin American and Caribbean Congress of Social Sciences, Universidad de Salamanca, Spain.

Análisis sobre el uso de redes sociales académicas por parte de investigadores adscritos al área de Sociología dentro del Sistema Nacional de Investigadores (SNI) en México.
*Trabajo presentado en el 4º Congreso Latinoamericano y Caribeño de Ciencias Sociales, Universidad de Salamanca, España.
Searching for the best agarose candidate from genus Gracilaria, Eucheuma, Gelidium and local brands
Creators: name: Efendi, Ferry
name: Dr. Nursalam
Publisher: name: figshare
Year: 2017
Subjects: subject: Biomarkers
subject: 30405 Molecular Medicine
subject: FOS: Basic medicine
subject: Molecular Biology

description: ObjectiveTo explore the potential of local agar of genus Gracilaria, Eucheuma, Gelidium and local brands as an alternative for imported agarose for DNA electrophoresis, and to examine their ability related to separation and migration of DNA fragments in DNA electrophoresis.MethodsTheir performance at various concentrations were compared via an experimental study with a specific brand of imported commercial agarose used in molecular biology research. The measured variables were separation and migration during electrophoresis of a DNA fragment.ResultsThe local agar genus Gracilaria gigas, Gelidium, brand “B” and brand “S” could separate DNA fragments at a concentration between 1% and 2%, with an optimum concentration of 2% w/v, as good as a specific brand of imported commercial agarose.ConclusionsTheir performance were very close to that of commercial agarose and can still be improved by further agar purification as well as by pH and sulfur control.
title: A mindfulness-based stress prevention training for medical students (MediMind)
title: study protocol for a randomized controlled trial
titleType: Subtitle
Creators: name: Kuhlmann, Sophie Merle
name: Bürger, Arne
name: Esser, Günter
name: Hammerle, Florian
Publisher: name: Universität Potsdam
Year: 2020

description: Background: Medical training is very demanding and associated with a high prevalence of psychological distress. Compared to the general population, medical students are at a greater risk of developing a psychological disorder. Various attempts of stress management training in medical school have achieved positive results on minimizing psychological distress; however, there are often limitations. Therefore, the use of a rigorous scientific method is needed. The present study protocol describes a randomized controlled trial to examine the effectiveness of a specifically developed mindfulness-based stress prevention training for medical students that includes selected elements of cognitive behavioral strategies (MediMind). Methods/Design: This study protocol presents a prospective randomized controlled trial, involving four assessment time points: baseline, post-intervention, one-year follow-up and five-year follow-up. The aims include evaluating the effect on stress, coping, psychological morbidity and personality traits with validated measures. Participants are allocated randomly to one of three conditions: MediMind, Autogenic Training or control group. Eligible participants are medical or dental students in the second or eighth semester of a German university. They form a population of approximately 420 students in each academic term. A final total sample size of 126 (at five-year follow-up) is targeted. The trainings (MediMind and Autogenic Training) comprise five weekly sessions lasting 90 minutes each. MediMind will be offered to participants of the control group once the five-year follow-up is completed. The allotment is randomized with a stratified allocation ratio by course of studies, semester, and gender. After descriptive statistics have been evaluated, inferential statistical analysis will be carried out with a repeated measures ANOVA-design with interactions between time and group. Effect sizes will be calculated using partial η-square values. Discussion: Potential limitations of this study are voluntary participation and the risk of attrition, especially concerning participants that are allocated to the control group. Strengths are the study design, namely random allocation, follow-up assessment, the use of control groups and inclusion of participants at different stages of medical training with the possibility of differential analysis.
description: Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe, 820
Multi-Scale Thermal-hydraulic Developments for the Detailed Analysis of the Flow Conditions within the Reactor Pressure Vessel of Pressurized Water Reactors
Creators: name: Zhang, Kanglong
Publisher: name: Karlsruhe
Year: 2020

description: Die mehrskalige thermohydraulische Analyse und die Entwicklung von mehrskaligen thermohydraulisch gekoppelten Programmen haben sich in den letzten Jahren zu einem vielversprechenden Gebiet im Bereich der Reaktortechnik entwickelt. Sie zielen darauf ab, die Fähigkeiten der thermohydraulischen Simulationswerkzeuge zu verbessern und die thermohydraulischen Phänomene in den Kernkraftsystemen umfassender zu beschreiben. Die mehrskalige thermohydraulische Simulation eines Druckwasserreaktors (PWR) bildet den Schwerpunkt dieser Arbeit. Eine generische Klassifizierung der verschiedenen Multi-Skalen-Kopplungsansätze wird vorgeschlagen und die gekoppelten Programme und Methoden werden verglichen. Die Dissertation entwickelt zwei mehrskalige thermohydraulische Kopplungssysteme: 1) die Verbindung des Systemcodes TRACE der US Nuclear Regulatory Commission (NRC) mit dem Unterkanalprogramm SubChanFlow (SCF) des Karlsruher Instituts für Technologie (KIT) unter Verwendung einer externen Kommunikationsschnittstelle (ECI); 2) die Verbindung des US-amerikanischen NRC-Systemcodes TRACE mit dem französischen Open-Source-CFD-Code TrioCFD unter Verwendung der ICoCo-Methode (Interface for Code Coupling). Die Kopplung TRACE / SCF-ECI wurde als serverloses, paralleles und explizites Kopplungssystem entwickelt, das die Methode der Domänenzerlegung anwendet. Ein neu entwickeltes Toolkit löst dabei die Feldzuordnungsprobleme. Dieses System wurde anhand eines akademischen Kühlmittelmischproblems für einen VVER-1000 als Referenz verifiziert und validiert. Es zeigt sich, dass der gekoppelte Code die Vermischung des Kühlmittels im Reaktordruckbehälter genauer vorhersagen kann. Darüber hinaus wurden die gekoppelten Codes optimiert, um effizienter zu arbeiten. Die Kopplung von TRACE / TrioCFD mithilfe von ICoCo wurde als explizites Server-Client-Kopplungssystem entwickelt, das die domänenübergreifende Methode anwendet und die SALOME MED-Kopplungs-Bibliothek verwendet, um die Feldzuordnung und den Datentransfer zwischen verschiedenen Volumenzellen zu verwalten. Eine neuartige DIAS-Methode (Dynamic-Implicit-Additional-Source) wurde implementiert. Dabei werden die von der MED-Bibliothek aus TrioCFD übersetzten Felder für die Kühlmittelgeschwindigkeit, den Druck, die Kühlmitteltemperatur und die Borkonzentration verwendet, um die vier entsprechenden Felder in TRACE abzubilden. Die Übertragung findet in der gesamten überlappenden Domäne statt. Das Ergebnis wird mit dem VVER-1000-Referenzwert für die Kühlmittelvermischung verglichen, und die verbesserte Fähigkeit der Codes, das Mischen von Kühlmittel im Reaktordruckbehälter vorherzusagen, wird aufgezeigt.
Balancing stratigraphic and structural controls on basin inversion.
Creators: name: Oldfield, Simon
name: Paton, Douglas A.
name: Bramham, Emma K.
name: Torvela, Taija
name: Mora, Andres
Publisher: name: figshare
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: 40312 Structural Geology
subject: 40309 Petroleum and Coal Geology
subject: 40407 Seismology and Seismic Exploration
subject: 40313 Tectonics

description: Presented at AAPG ICE 2017, London, UK
Abstract:Orogens often exhibit many aspects of former extensional terranes. Pre-existing strength heterogeneities may promote or inhibit the accumulation of strain, greatly affecting the local expression of features. This challenges our ability to propagate interpretations into areas of limited data constraint.
Using the frontal range of the Eastern Cordillera, Colombia, we discuss the extent of interaction between exposed compressional geometries and the underlying, partially re-activated, extensional terrane.
Depositional patterns, placing greater thickness of shales towards paleo-fault centres, provides greater support for an overlying competent beam, altering the wavelength of frontal folding. This contrasts with harpoon structure geometries locally, affecting the potential reservoir geometries.
Relationships between thrust nappe length and extensional terrane fault spacing are suggested. These two controls on the geometry of the system suggest that a balance exists between lithological and structural controls on resultant geometries.
Applying this understanding to areas not yet surveyed, allows improved targeting of future work and earlier identification of variation of controls.
title: Vergleich der Beanspruchung einer Faser- und Stahlseilbewickelten Steiltrommel
Creators: name: Stök, M.
Publisher: name: Universitätsbibliothek der TU Clausthal
Year: 2019

description: Die Belastung auf eine Seiltrommel durch die Bewicklung mit einem Faser- oder Stahlseil unterscheiden sich aufgrund der unterschiedlichen Seileigenschaften. Für eine bestehende Seiltrommel wird untersucht, welchen Einfluss die Verwendung eines Faserseils anstelle eines Stahlseils hat. Viele Faktoren haben einen Einfluss auf die Lasten, sodass für jedes Seiltrommelsystem eine individuelle Betrachtung notwendig ist.
description: The drum load caused by a fibre or steel rope differs due to different properties. To examine the influence of the different ropes on an existing construction the stress caused by the winding pack are compared and evaluated. Many contradicting influences to the drum load necessitate an individual consideration for each rope drum system.
µ-CT Untersuchungen an heimischen Holzarten
Creators: name: Thomann, Yi
name: Thomann, Ralf
Publisher: name: Zenodo
Year: 2022
Subjects: µ-CT
Kiefer
Eiche
Linde
Zwetschgenholz mit
Robinie
Rotbuche
Platane

description: µ-CT Gerät: SkyScan 1272 CT Segmentierung: Avizo 9.5 EM Version Kantenlänge der Würfel: 4.5 mm
Enhancing Students' Moral Development through Counseling by Christian Religious Education Teachers
Creators: name: Nurani Situmorang*
name: Bintang Yemima Sinaga
name: Gus Irawan Simanjuntak
Publisher: name: Zenodo
Year: 2023
Subjects: Moral Development, Counseling, Teachers.

description: Abstract: This study aims to explore the impact of guidance/counseling by teachers on students' moral development in class VIII-1 of SMP Negeri 2 Sei Bamban. The population studied consists of 32 students from class VIII-1. Data collection methods utilize Likert model questionnaires, employed to measure individuals' or groups' attitudes, opinions, and perceptions towards social phenomena. Data analysis involves four stages: (a) planning, (b) action implementation, (c) evaluation, and (d) reflection. The analysis results indicate a significant improvement in the average scores of guidance/counseling questionnaires from cycle I to cycle III. The average scores increased from 3.20 in cycle I to 3.41 in cycle II and reached 3.56 in cycle III. Additionally, the correlation between teacher guidance/counseling and students' moral development also increased from cycle I to cycle III. The correlation increased from 73.9% in cycle I to 74.3% in cycle II and reached 86.5% in cycle III.
Fault Length, Connectivity and Reservoir Compartmentalisation – Testing Workflows with Seismic Forward Modelling
Creators: name: Oldfield, Simon
name: Paton, Douglas A.
name: Bramham, Emma K.
Publisher: name: figshare
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: 40312 Structural Geology
subject: 40309 Petroleum and Coal Geology
subject: 40313 Tectonics
subject: 40407 Seismology and Seismic Exploration

description: Presented at AAPG ACE 2017, Houston, USA.
Abstract:Reservoir compartmentalisation is a critical factor in determining suitable development strategies and thus economic viability of prospects. The degree of compartmentalisation is controlled by the geometry, continuity, linkage and transmissibility of individual faults.
Research to date has focussed on the transmissibility and juxtaposition analysis of faults, however our understanding of uncertainty and flow sensitivity to interpreted fault geometry and continuity in seismic data has been less robustly investigated.
We use seismic forward modelling to determine effective methods of defining fault tip locations. Using a comparison of individual and combinations of geometric and complex trace seismic attributes, we analyse fault-tip prediction for a range of fault displacement profiles.
Our results suggest that rather than defining a single attribute interpretation of fault-tip location, combination of multiple interpretations from selected individual and combined methods provides an envelope and probability distribution, within which an interpreter may expect the fault-tip.
This approach to constraining fault-tip location supports a progression towards robust inclusion of multiple geometric scenarios in reservoir simulation.
Ações afirmativas para pessoas surdas no processo de escolarização
Creators: name: Lins, Heloísa A. Matos
name: Nascimento, Lilian Cristine Ribeiro
name: Souza, Regina Maria De
name: Santos, Gildenir Carolino
Publisher: name: figshare
Year: 2017
Subjects: subject: Education
subject: 130106 Secondary Education
subject: FOS: Educational sciences
subject: 130199 Education systems not elsewhere classified

description: O livro "Ações afirmativas para pessoas surdas no processo de escolarização", da série Setembro Azul, na sua caraterística de sabedoria prática, apresenta com muita propriedade, ao lado das reflexões teóricas e éticas, o que deve e pode ser feito imediatamente, enquanto se luta pela implantação do bilinguismo nas universidades, escolas e na sociedade. Este trabalho é fruto e resultado do evento V Setembro Azul, que nesta obra destacamos como uma série.
Discovery of novel 2-aminopyridine derivatives as ROS1 and ALK dual inhibitors to combat drug-resistant mutants including ROS1G2032R and ALKG1202R
Creators: name: Liu, Siming
name: Huang, Chuan
name: Huang, Chunhui
name: Huang, Yaqi
name: Yu, Yonghuan
name: Wu, Guowu
name: Guo, Fengqiu
name: Jiang, Ying
name: Wan, Shanhe
name: Zhu, Zhengguang
name: Tian, Yuanxin
name: Zhu, Jianghua
name: Zhang, Jiajie
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Clinical treatment by FDA-approved ROS1/ALK inhibitor Crizotinib significantly improved the therapeutic outcomes. However, the emergence of drug resistance, especially driven by acquired mutations, have become an inevitable problem and worsened the clinical effects of Crizotinib. To combat drug resistance, some novel 2-aminopyridine derivatives were designed rationally based on molecular simulation, then synthesised and subjected to biological test. The preferred spiro derivative C01 exhibited remarkable activity against CD74-ROS1G2032R cell with an IC50 value of 42.3 nM, which was about 30-fold more potent than Crizotinib. Moreover, C01 also potently inhibited enzymatic activity against clinically Crizotinib-resistant ALKG1202R, harbouring a 10-fold potency superior to Crizotinib. Furthermore, molecular dynamic disclosed that introducing the spiro group could reduce the steric hindrance with bulky side chain (Arginine) in solvent region of ROS1G2032R, which explained the sensitivity of C01 to drug-resistant mutant. These results indicated a path forward for the generation of anti Crizotinib-resistant ROS1/ALK dual inhibitors. SAR of a series of 2-aminopyridine ROS1/ALK inhibitors was studied. The spiro derivatives exhibited remarkable dual ROS1/ALK activity. C01 potently inhibited Crizotinib-refractory ALKG1202R and ROS1G2032R mutants. Molecular simulations gave a probable explanation for the activity of C01.
Risk Screen of Freshwater Tropical Ornamental Fishes for the Conterminous United States
Creators: name: Hill, Jeffrey E.
name: Quenton M. Tuckett
name: Hardin, Scott
name: Lawson, Larry L.
name: Lawson, Katelyn M.
name: Ritch, Jared L.
name: Partridge, Lauren
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The trade in ornamental fish is increasingly viewed as a major source for the introduction of invasive species into the environment. However, few ornamental fishes are established and widespread in the conterminous United States, and fewer still are thought to cause noticeable environmental impacts. To better evaluate the risk of this pathway, we conducted a risk screen of 34 important freshwater ornamental fish species by using the Fish Invasiveness Screening Kit (FISK) version 2 for the conterminous United States. Screens from three to five independent assessors resulted in categorization of 91–100% of the species as noninvasive. The low climate match of these mostly tropical species largely confines establishment risk to subtropical regions, primarily peninsular Florida, and to isolated thermal refuges (e.g., geothermal springs) in otherwise unsuitable climates. Few data on impacts exist for tropical ornamental fish in the conterminous United States, and there is little evidence for the occurrence of large, long-term effects despite local impacts for a few species. Our results indicate that the freshwater tropical ornamental fish trade is less risky to the conterminous United States than has been concluded in most previous studies. Further risk assessment for management decisions might be required on a regional scale or for localized, high-risk situations. Received November 3, 2016; accepted March 23, 2017
Partial List of Publications on Dairying Issued in the United States, 1900 to June,1923
Creators: name: Sherfy, Carrie B.
name: Sherfy, Carrie B.
Publisher: name: Unknown
Year: 1923
Subjects: subject: Agricultural and Food Policy
subject: Food Consumption/Nutrition/Food Safety
subject: Livestock Production/Industries
subject: Marketing
subject: FOS: Economics and business
subject: Production Economics
subject: Research and Development/Tech Change/Emerging Technologies

description: This list of dairy literature was compiled primarily for use in connection with the World's Dairy Congress, to be held in the United States, in October, 1923, and no claim is made for completeness. Contents: Part 1. Publications of the State Agricultural Experiment Stations, 1900 to June, 1923, inclusive; Part 2, Publications of the United States Department of Agriculture, 1900 to June, 1923, inclusive; Part 3. Books issued or revised since 1908; Part 4. Periodicals; Part 5. Subject List
CONTINUOUS INTEGRATION AND VERSION CONTROL: A SYSTEMATIC REVIEW - PT/BR
Creators: name: Rocha, Fabio Gomes
name: Menezes, Pablo Marques
name: Rogério Patrício Chagas Do Nascimento
name: Methanias Colaço Rodrigues Junior
name: Adicinéia Aparecida De Oliveira
Publisher: name: figshare
Year: 2017
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: Fast delivery of functional parts has been one of the most complex challenges in the software development process. This article aims at using a systematic review of literature between 2005 and 2015, to identify the state of the art on the technical continuum integration and tools of version control, Subversion and Git, identified as the most used. The works found are analyzed and presented in this article
Additional file 1 of Self-reported sleep characteristics associated with dementia among rural-dwelling Chinese older adults: a population-based study
Creators: name: Liu, Rui
name: Tang, Shi
name: Wang, Yongxiang
name: Dong, Yi
name: Hou, Tingting
name: Ren, Yifei
name: Cong, Lin
name: Liu, Keke
name: Qin, Yu
name: Sindi, Shireen
name: Du, Yifeng
name: Qiu, Chengxuan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Cancer
subject: Mental Health

description: Additional file 1: Supplementary Table 1. Associations of self-reported sleep characteristics with all-cause dementia and Alzheimer’s disease stratified by age groups (n = 4742). Supplementary Table 2. Associations of self-reported sleep characteristics with all-cause dementia and Alzheimer’s disease stratified by sex (n = 4742). Supplementary Table 3. Associations of self-reported sleep characteristics with all-cause dementia and Alzheimer’s disease stratified by education (n = 4742). Supplementary Table 4. Associations of self-reported sleep characteristics with all-cause dementia and Alzheimer’s disease stratified by APOE genotype (n = 4599).
Republic of Learning at Camden Think and Do Documentation
Creators: name: Lane, Giles
name: Jacobs, Rachel
Publisher: name: Zenodo
Year: 2019
Subjects: climate change
art
participation

description: A bookleteer.com booklet documenting a Republic of Learning workshop held in November 2019 at Camden Think & Do, a pop-up community space in Kentish Town, London. Published by Proboscis. Browse the online version: https://bookleteer.com/book.html?id=3482#page/1/mode/2up Download the PDF: https://bookleteer.com/publication.html?id=3482
Evolution of maturity levels of the particle surface and bulk during soot growth and oxidation in a flame
Creators: name: K. O. Johansson
name: F. El Gabaly
name: P. E. Schrader
name: M. F. Campbell
name: H. A. Michelsen
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: We performed a study of the evolution of soot composition and fine structure, i.e., maturity level, in an atmospheric ethylene-air diffusion flame. We used laser-induced incandescence (LII) to provide information about maturity level of the bulk primary particle and X-ray photoelectron spectroscopy (XPS) to provide complementary information about particle-surface-maturity level. The results demonstrate that the bulk material and the particle surface evolve separately in the flame. Increased soot-maturity level is associated with increased long-range order of the particle fine structure. This increased order leads to an increase in the absorption cross-section in the visible and near-infrared and a shift of the absorption to longer wavelengths with increasing maturity level of the bulk particle. These trends result in a decrease in the dispersion exponent (?) and increase in the absorption cross-section scaling factor (?), as inferred from LII measurements. LII measurements demonstrate that bulk-maturity level increases with height-above-the-burner (HAB) until it reaches a plateau in the center of the flame at the maximum in the soot volume fraction. Bulk-maturity level only slightly decreases as soot is oxidized at larger HABs. Increased maturity level also leads to an increase in long-range sp2 hybridization. XPS measurements of the sp2/defect ratio demonstrate an increase in soot surface-maturity level with increasing HAB, but the surface-maturity level increases more gradually with HAB than the bulk-maturity level. Whereas the bulk-fine-structure order decreases slightly in the oxidation region, the surface order decreases dramatically, indicating that oxidation occurs preferentially at the surface under these conditions. Copyright © The Authors. Published with license by American Association for Aerosol Research
title: 03_0583
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Additional file 8 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Creators: name: Pan, Bohu
name: Ren, Luyao
name: Onuchic, Vitor
name: Guan, Meijian
name: Kusko, Rebecca
name: Bruinsma, Steve
name: Trigg, Len
name: Scherer, Andreas
name: Ning, Baitang
name: Zhang, Chaoyang
name: Glidewell-Kenney, Christine
name: Xiao, Chunlin
name: Donaldson, Eric
name: Sedlazeck, Fritz J.
name: Schroth, Gary
name: Yavas, Gokhan
name: Grunenwald, Haiying
name: Chen, Haodong
name: Meinholz, Heather
name: Meehan, Joe
name: Wang, Jing
name: Yang, Jingcheng
name: Foox, Jonathan
name: Shang, Jun
name: Miclaus, Kelci
name: Dong, Lianhua
name: Shi, Leming
name: Mohiyuddin, Marghoob
name: Pirooznia, Mehdi
name: Gong, Ping
name: Golshani, Rooz
name: Wolfinger, Russ
name: Lababidi, Samir
name: Sahraeian, Sayed Mohammad Ebrahim
name: Sherry, Steve
name: Han, Tao
name: Chen, Tao
name: Shi, Tieliu
name: Hou, Wanwan
name: Ge, Weigong
name: Zou, Wen
name: Guo, Wenjing
name: Bao, Wenjun
name: Xiao, Wenzhong
name: Fan, Xiaohui
name: Gondo, Yoichi
name: Yu, Ying
name: Zhao, Yongmei
name: Su, Zhenqiang
name: Liu, Zhichao
name: Tong, Weida
name: Xiao, Wenming
name: Zook, Justin M.
name: Zheng, Yuanting
name: Hong, Huixiao
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 8: Supplementary figures Fig. S1-S42.
Evolution of particle surface and bulk maturity level during soot growth and oxidation in a flame
Creators: name: K. O. Johansson
name: F. El Gabaly
name: P. E. Schrader
name: M. F. Campbell
name: H. A. Michelsen
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: We performed a study of the evolution of soot composition and fine structure, i.e., maturity level, in an atmospheric ethylene-air diffusion flame. We used laser-induced incandescence (LII) to provide information about maturity level of the bulk primary particle and X-ray photoelectron spectroscopy (XPS) to provide complementary information about particle-surface-maturity level. The results demonstrate that the bulk material and the particle surface evolve separately in the flame. Increased soot-maturity level is associated with increased long-range order of the particle fine structure. This increased order leads to an increase in the absorption cross section in the visible and near infrared and a shift of the absorption to longer wavelengths with increasing maturity level of the bulk particle. These trends result in a decrease in the dispersion exponent (ξ) and increase in the absorption cross section scaling factor (β), as inferred from LII measurements. LII measurements demonstrate that bulk-maturity level increases with height-above-the-burner (HAB) until it reaches a plateau in the center of the flame at the maximum in the soot volume fraction. Bulk-maturity level only slightly decreases as soot is oxidized at larger HABs. Increased maturity level also leads to an increase in long-range sp2 hybridization. XPS measurements of the sp2/defect ratio demonstrate an increase in soot surface-maturity level with increasing HAB, but the surface-maturity level increases more gradually with HAB than the bulk-maturity level. Whereas the bulk-fine-structure order decreases slightly in the oxidation region, the surface order decreases dramatically, indicating that oxidation occurs preferentially at the surface under these conditions.
A SURVEY ON AGILE METHODOLOGIES AND ITS RELATIONSHIP WITH THE REQUIREMENT-BASED TECHNIQUES
Creators: name: Rocha, Fabio Gomes
name: Rogério Patrício Chagas Do Nascimento
name: Methanias Colaço Rodrigues Junior
Publisher: name: figshare
Year: 2017
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: Requirements elicitation is one of the early stages of any software development methodology, leading directly into the product to be developed. In this research presents a survey intent to identify the techniques of requirements elicitation, when using agile methods, verifying the prevalence by iterative elicitation and as technical meetings. The conclusions indicated that most information technology professionals adopt Scrum as agile method, and elicitation of requirements made under incrementally.
Additional file 2 of RNA N6-methyladenosine reader IGF2BP2 promotes lymphatic metastasis and epithelial-mesenchymal transition of head and neck squamous carcinoma cells via stabilizing slug mRNA in an m6A-dependent manner
Creators: name: Yu, Dan
name: Pan, Min
name: Li, Yanshi
name: Lu, Tao
name: Wang, Zhihai
name: Liu, Chuan
name: Hu, Guohua
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2.
Bias and size corrections in extreme value modeling
Creators: name: Roodman, David
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology

description: Extreme value theory models have found applications in myriad fields. Maximum likelihood (ML) is attractive for fitting the models because it is statistically efficient and flexible. However, in small samples, ML is biased to O(N−1) and some classical hypothesis tests suffer from size distortions. This paper derives the analytical Cox–Snell bias correction for the generalized extreme value (GEV) model, and for the model's extension to multiple order statistics (GEVr). Using simulations, the paper compares this correction to bootstrap-based bias corrections, for the generalized Pareto, GEV, and GEVr. It then compares eight approaches to inference with respect to primary parameters and extreme quantiles, some including corrections. The Cox–Snell correction is not markedly superior to bootstrap-based correction. The likelihood ratio test appears most accurately sized. The methods are applied to the distribution of geomagnetic storms.