cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A Phosphinine‐derived 1‐Phospha‐7‐bora‐norbornadiene: Frustrated Lewis Pair Type Activation of Triple Bonds
Creators: name: Leitl, J.
name: Jupp, A. R.
name: Habraken, E. R. M.
name: Streitferdt, V.
name: Coburger, P.
name: Scott, D. J.
name: Gschwind, Ruth M.
name: Müller, C.
name: Slootweg, J. C.
name: Wolf, Robert
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: X-RAY CRYSTAL; LAMBDA(4)-PHOSPHININE ANION; CATALYZED HYDROFORMYLATION; COVALENT RADII; REACTIVITY; COMPLEXES; 2,4,6-TRIPHENYLPHOSPHININE; LIGANDS; COORDINATION; REDUCTION; alkyne; frustrated Lewis pair; nitrile; norbornadiene; phosphinine
subject: 540 Chemie

description: Salt metathesis of 1-methyl-2,4,6-triphenylphosphacyclohexadienyl lithium and chlorobis(pentafluorophenyl)borane affords a 1-phospha-7-bora-norbornadiene derivative 2. The C equivalent to N triple bonds of nitriles insert into the P-B bond of 2 with concomitant C-B bond cleavage, whereas the C equivalent to C bonds of phenylacetylenes react with 2 to form lambda(4)-phosphabarrelenes. Even though 2 must formally be regarded as a classical Lewis adduct, the C equivalent to N and C equivalent to C activation processes observed (and the mild conditions under which they occur) are reminiscent of the reactivity of frustrated Lewis pairs. Indeed, NMR and computational studies give insight into the mechanism of the reactions and reveal the labile nature of the phosphorus-boron bond in 2, which is also suggested by detailed NMR spectroscopic studies on this compound. Nitrile insertion is thus preceded by ring opening of the bicycle of 2 through P-B bond splitting with a low energy barrier. By contrast, the reaction with alkynes involves formation of a reactive zwitterionic methylphosphininium borate intermediate, which readily undergoes alkyne 1,4-addition.
MOESM3 of Safety, efficacy and pharmacokinetic evaluations of a new coated chloroquine tablet in a single-arm open-label non-comparative trial in Brazil: a step towards a user-friendly malaria vivax treatment
Creators: name: Dhelio Pereira
name: AndrĂŠ Daher
name: Zanini, Graziela
name: Maia, Ivan
name: Lais Fonseca
name: Pitta, Luciana
name: Rosilene Ruffato
name: Marchesini, Paola
name: Fontes, Cor
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 60506 Virology

description: Additional file 3. Patientâ  s flow chart. The figure presents patientâ  s flow diagram from screening to analysis, besides the reasons for not including and study premature discontinuation.
Additional file 11: of AIP1 is a novel Agenet/Tudor domain protein from Arabidopsis that interacts with regulators of DNA replication, transcription and chromatin remodeling
Creators: name: Brasil, Juliana
name: Luiz Cabral
name: Eloy, Nubia
name: Primo, Luiza
name: Barroso-Neto, Ito
name: LetĂ­Cia Grangeiro
name: Gonzalez, Nathalie
name: InzĂŠ, Dirk
name: Ferreira, Paulo
name: Hemerly, Adriana
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Proteins Identified by Tandem Affinity Purification using AIP1 as bait. (PDF 100 kb)
Additional file 3: Table S2. of Tumour stage distribution and survival of malignant melanoma in Germany 2002–2011
Creators: name: Schoffer, Olaf
name: Schülein, Stefanie
name: Arand, Gerlinde
name: Arnholdt, Hans
name: Baaske, Dieter
name: Bargou, Ralf
name: Becker, Nikolaus
name: Beckmann, Matthias
name: Bodack, Yves
name: Böhme, Beatrix
name: Bozkurt, Tayfun
name: Breitsprecher, Regine
name: Buchali, Andre
name: Burger, Elke
name: Burger, Ulrike
name: Dommisch, Klaus
name: Elsner, Gudrun
name: Fernschild, Karin
name: Flintzer, Ulrike
name: Funke, Uwe
name: Gerken, Michael
name: Göbel, Hubert
name: Grobe, Norbert
name: Gumpp, Vera
name: Heinzerling, Lucie
name: Kempfer, Lana
name: Kiani, Alexander
name: Klinkhammer-Schalke, Monika
name: Klöcking, Sabine
name: Kreibich, Ute
name: Knabner, Katrin
name: Kuhn, Peter
name: Lutze, Stine
name: Mäder, Uwe
name: Maisel, Tanja
name: Maschke, Jan
name: Middeke, Martin
name: Neubauer, Andreas
name: Niedostatek, Antje
name: Opazo-Saez, Anabelle
name: Peters, Christoph
name: Schell, Beatrice
name: Schenkirsch, Gerhard
name: Schmalenberg, Harald
name: Schmidt, Peter
name: Schneider, Constanze
name: Schubotz, Birgit
name: Seide, Anika
name: Strecker, Paul
name: Taubenheim, Sabine
name: Wackes, Matthias
name: Weiß, Steffen
name: Welke, Claudia
name: Werner, Carmen
name: Wittekind, Christian
name: Wulff, Jörg
name: Zettl, Heike
name: Klug, Stefanie
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer

description: Malignant melanoma patients aged 35 years and above by age at diagnosis, sex, UICC stage, year of diagnosis, place of residence and ‘diagnosis during screening’, N = 34 739 (UICC 0 and X excluded) (DOCX 40 kb)
MOESM2 of Safety, efficacy and pharmacokinetic evaluations of a new coated chloroquine tablet in a single-arm open-label non-comparative trial in Brazil: a step towards a user-friendly malaria vivax treatment
Creators: name: Dhelio Pereira
name: AndrĂŠ Daher
name: Zanini, Graziela
name: Maia, Ivan
name: Lais Fonseca
name: Pitta, Luciana
name: Rosilene Ruffato
name: Marchesini, Paola
name: Fontes, Cor
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 2. Treatment schedule. The table presents the number of tablets per drug and day according weight range.
Self-assembly of hollow organic nanotubes driven by arene regioisomerism
Creators: name: Alegre-Requena, Juan V.
name: Herrera, Raquel P.
name: Diaz Diaz, David
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: SOL-GEL TRANSCRIPTION; BASIS-SETS; HELICAL RIBBON; TEMPLATE; ORGANOGEL; CREATION; OPTIMIZATION; DERIVATIVES; SOLVENTS; gels; nanotubes; regioisomers; self-assembly; supramolecular chemistry
subject: 540 Chemie

description: Arene regioisomerism in low-molecular-weight gelators can be exploited as a tool to modulate the micro-structures of the corresponding xerogel networks by using the three different possible substitution patternsortho,metaandpara. This aromatic regioisomer-driven strategy has been used with a cholesterol-based gelator to prepare hollow self-assembled organic nanotubes (S-ONTs) with inside and outside diameters of ca. 35 and 140 nm, respectively. Electron microscopy imaging and theoretical calculations were employed to rationalize the formation mechanism of these S-ONTs. From the three possible regioisomers, only theortho-disubstituted cholesteryl-based gelator showed the optimal angle and distance between substituents to afford the formation of the cyclic assemblies required for nanotube growth by assembling 30-40 units of the gelator. This study opens fascinating opportunities to expand the synthesis of controllable and unique microstructures by modulating geometrical parameters through aromatic regioisomers.
Additional file 9: of AIP1 is a novel Agenet/Tudor domain protein from Arabidopsis that interacts with regulators of DNA replication, transcription and chromatin remodeling
Creators: name: Brasil, Juliana
name: Luiz Cabral
name: Eloy, Nubia
name: Primo, Luiza
name: Barroso-Neto, Ito
name: LetĂ­Cia Grangeiro
name: Gonzalez, Nathalie
name: InzĂŠ, Dirk
name: Ferreira, Paulo
name: Hemerly, Adriana
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Plant Biology
subject: Computational Biology

description: Parameters data from Structural Modeling in I-TASSER. (PDF 7 kb)
Additional file 2: of Glucose-6-phosphate dehydrogenase deficiency among malaria patients of Honduras: a descriptive study of archival blood samples
Creators: name: Zúñiga, Miguel
name: Mejía, Rosa
name: Sánchez, Ana
name: Sosa-Ochoa, Wilfredo
name: Fontecha, Gustavo
Publisher: name: Figshare
Year: 2015
Subjects: subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Flowchart with overall study findings.
Composetia Hartmann-Schroder 1985
Creators: name: Sato, Masanori
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Polychaeta
Phyllodocida
Nereididae
Composetia

description: Key to species of Composetia recorded from Japan
1 Notopodial prechaetal lobe present in anterior chaetigers..........................................2
– Notopodial prechaetal lobe absent throughout.......3
2 Jaws with three teeth in basal half separated by wide interval from double tooth near apical fang; 5 paragnaths in longitudinal series in area I............. C. moorei
– Jaws with four teeth without separated double tooth; 0 or 1 paragnath present in area I............ C. costae
3 Neuropodial heterogomph spinigers absent throughout.................................... C. hircinicola
– Neuropodial heterogomph spinigers present throughout............................................4
4 Heterogomph spinigers present among upper neurochaetae around chaetiger 5... C. tokashikiensis sp. nov.
– Heterogomph spinigers absent among upper neurochaetae throughout............. C. kumensis sp. nov.
description: Published as part of Sato, Masanori, 2020, Two New Species of Composetia (Annelida: Nereididae) from Small Estuaries in the Ryukyu Islands, Southern Japan, with a List of All Species Currently Belonging to Composetia, pp. 11-24 in Species Diversity 25 on page 23, DOI: 10.12782/specdiv.25.11, http://zenodo.org/record/3751625
title: Perceived movement of nonrigid motion patterns
Creators: name: Koerfer, Krischan
name: Lappe, Markus
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2023
Subjects: subject: 150 Psychology

description: Nonrigid materials such as liquids or smoke deform over time. Little is known about the visual perception of nonrigid motion other than that many motion cues associated with rigid motion perception are not reliable for nonrigid motion. Nonrigid motion patterns lack clear borders and their movement can be inconsistent with the motion of their parts. We developed a novel stimulus that creates a nonrigid vortex motion pattern in a random dot distribution and decouples the movement of the vortex from the first-order motion of the dots. We presented three moving vortices that entailed consecutively fewer motion cues, eliminating occlusion, motion borders, and velocity field gradients in the process. Subjects were well able to report the end position and travel path in all cases, showing that nonrigid motion is perceived through an analysis of the temporal evolution of visual motion patterns and does not require borders or speed differences. Adding a coherent global motion did not hamper perception, but adding local noise did, indicating that the visual system uses mid-level features that are on a local scale. We also found that participants judged the movement of the nonrigid motion patterns slower than a rigid control, revealing that speed perception was based on a combination of motion of the parts and movement of the pattern. We propose that the visual system uses the temporal evolution of a motion pattern for the perception of nonrigid motion and suggest a plausible mechanism based on the curl of the motion field.
description: Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Additional file 4: Table S3. of Tumour stage distribution and survival of malignant melanoma in Germany 2002–2011
Creators: name: Schoffer, Olaf
name: Schülein, Stefanie
name: Arand, Gerlinde
name: Arnholdt, Hans
name: Baaske, Dieter
name: Bargou, Ralf
name: Becker, Nikolaus
name: Beckmann, Matthias
name: Bodack, Yves
name: Böhme, Beatrix
name: Bozkurt, Tayfun
name: Breitsprecher, Regine
name: Buchali, Andre
name: Burger, Elke
name: Burger, Ulrike
name: Dommisch, Klaus
name: Elsner, Gudrun
name: Fernschild, Karin
name: Flintzer, Ulrike
name: Funke, Uwe
name: Gerken, Michael
name: Göbel, Hubert
name: Grobe, Norbert
name: Gumpp, Vera
name: Heinzerling, Lucie
name: Kempfer, Lana
name: Kiani, Alexander
name: Klinkhammer-Schalke, Monika
name: Klöcking, Sabine
name: Kreibich, Ute
name: Knabner, Katrin
name: Kuhn, Peter
name: Lutze, Stine
name: Mäder, Uwe
name: Maisel, Tanja
name: Maschke, Jan
name: Middeke, Martin
name: Neubauer, Andreas
name: Niedostatek, Antje
name: Opazo-Saez, Anabelle
name: Peters, Christoph
name: Schell, Beatrice
name: Schenkirsch, Gerhard
name: Schmalenberg, Harald
name: Schmidt, Peter
name: Schneider, Constanze
name: Schubotz, Birgit
name: Seide, Anika
name: Strecker, Paul
name: Taubenheim, Sabine
name: Wackes, Matthias
name: Weiß, Steffen
name: Welke, Claudia
name: Werner, Carmen
name: Wittekind, Christian
name: Wulff, Jörg
name: Zettl, Heike
name: Klug, Stefanie
Publisher: name: Figshare
Year: 2016
Subjects: subject: Cell Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer

description: Relative 5-year survival of malignant melanoma patients diagnosed between 2002 and 2011, overall (UICC 0-IV, X) (N = 60 672) and for patients with invasive tumours (UICC I – IV, X) stratified by age, sex, UICC stage, ‘diagnosis during screening’ and place of residence (N = 49 351) (DOCX 39 kb)
Photocatalytic Synthesis of Polycyclic Indolones
Creators: name: Saget, Tanguy
name: König, Burkhard
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: C-H FUNCTIONALIZATION; ELECTRON-RICH HETEROCYCLES; PHOTOREDOX CATALYSIS; ENANTIOSELECTIVE SYNTHESIS; INDOLES; ALKALOIDS; (-)-LEUCONOXINE; HETEROARENES; ALKYLATION; ACTIVATION; C-H functionalization; indoles; indolones; photoredox catalysis; visible light
subject: 540 Chemie

description: In this work, a photocatalytic strategy for a rapid and modular access to polycyclic indolones starting from readily available indoles is reported. This strategy relies on the use of redox-active esters in combination with an iridium-based photocatalyst under visible-light irradiation. The generation of alkyl radicals through decarboxylative single electron reductions enables intramolecular homolytic aromatic substitutions with a pending indole moiety to afford pyrrolo- and pyridoindolone derivatives under mild conditions. Furthermore, it was demonstrated that these radicals could also be engaged into cascades consisting of an intermolecular Giese-type addition followed by an intramolecular homolytic aromatic substitution to rapidly assemble valuable azepinoindolones.
Thermodynamic, Spatial and Methodological Considerations for the Manufacturing of Therapeutic Polymer Nanoparticles
Creators: name: Goepferich, Achim
name: Maslanka-Figueroa, Sara
name: Fleischmann, Daniel
name: Beck, Sebastian
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: SOLUBILITY PARAMETERS; PLGA NANOPARTICLES; POLYETHYLENE-GLYCOL; RATIONAL DESIGN; PIRFENIDONE; DRUG; PEG; NANOPRECIPITATION; MICELLES; encapsulation; microfluidics; nanoprecipitation; pirfenidone; polymeric nanoparticles
subject: 615 Pharmazie

description: Purpose Evaluate fundamental parameters that dictate the effectiveness of drug loading. Methods A model water-soluble drug lacking ionizable groups, pirfenidone (PFD), was encapsulated through nanoprecipitation in poly(ethylene glycol)-poly(lactic acid) (PEG-PLA)-poly(lactic-co-glycolic acid) (PLGA) NPs. Firstly, the thermodynamic parameters predicting drug-polymer miscibility were determined to assess the system's suitability. Then, the encapsulation was evaluated experimentally by two different techniques, bulk and microfluidic (MF) nanoprecipitation. Additionally, the number of molecules that fit in a particle core were calculated and the loading determined experimentally for different core sizes. Lastly, the effect of co-encapsulation of alpha-lipoic acid (LA), a drug with complementary therapeutic effects and enhanced lipophilicity, was evaluated. Results The thermodynamic miscibility parameters predicted a good suitability of the selected system. MF manufacturing enhanced the encapsulation efficiency by 60-90% and achieved a 2-fold higher NP cellular uptake. Considering spatial constrictions for drug encapsulation and increasing the size of the PLGA core the number of PFD molecules per NP was raised from under 500 to up to 2000. More so, the co-encapsulation of LA increased the number of drug molecules per particle by 96%, with no interference with the release profile. Conclusions Thermodynamic, spatial and methodological parameters should be considered to optimize drug encapsulation.
Additional file 1: Table S1. of Mortality in the Melbourne injecting drug user cohort study (MIX)
Creators: name: Dhanya Nambiar
name: Agius, Paul A.
name: Stoové, Mark
name: Hickman, Matthew
name: Dietze, Paul
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Computational Biology

description: Time-varying socio-demographic, risk and health service utilisation factors associated with mortality among PWID in Melbourne (n = 665). (DOC 99 kb)
Additional file 2: of AIP1 is a novel Agenet/Tudor domain protein from Arabidopsis that interacts with regulators of DNA replication, transcription and chromatin remodeling
Creators: name: Brasil, Juliana
name: Luiz Cabral
name: Eloy, Nubia
name: Primo, Luiza
name: Barroso-Neto, Ito
name: LetĂ­Cia Grangeiro
name: Gonzalez, Nathalie
name: InzĂŠ, Dirk
name: Ferreira, Paulo
name: Hemerly, Adriana
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Modeled structure of Agenet/Tudor domains from plant proteins. (PDF 925 kb)
MOESM3 of Engineering Yarrowia lipolytica to produce biodiesel from raw starch
Creators: name: Ledesma-Amaro, Rodrigo
name: Dulermo, Thierry
name: Nicaud, Jean
Publisher: name: Figshare
Year: 2015
Subjects: subject: Molecular Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Additional file 3: Figure S2.
Additional file 8: of AIP1 is a novel Agenet/Tudor domain protein from Arabidopsis that interacts with regulators of DNA replication, transcription and chromatin remodeling
Creators: name: Brasil, Juliana
name: Luiz Cabral
name: Eloy, Nubia
name: Primo, Luiza
name: Barroso-Neto, Ito
name: LetĂ­Cia Grangeiro
name: Gonzalez, Nathalie
name: InzĂŠ, Dirk
name: Ferreira, Paulo
name: Hemerly, Adriana
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: Parameters data from Structural similarity in ESPrint using the second Agenet/Tudor domain from AIP1 protein as query. (PDF 170 kb)
MOESM4 of Safety, efficacy and pharmacokinetic evaluations of a new coated chloroquine tablet in a single-arm open-label non-comparative trial in Brazil: a step towards a user-friendly malaria vivax treatment
Creators: name: Dhelio Pereira
name: AndrĂŠ Daher
name: Zanini, Graziela
name: Maia, Ivan
name: Lais Fonseca
name: Pitta, Luciana
name: Rosilene Ruffato
name: Marchesini, Paola
name: Fontes, Cor
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 4. Adverse events counts reported per day. The table provides detailed information on the absolute numbers and distribution of adverse events during the study.
Additional file 1: of Glucose-6-phosphate dehydrogenase deficiency among malaria patients of Honduras: a descriptive study of archival blood samples
Creators: name: Zúñiga, Miguel
name: Mejía, Rosa
name: Sánchez, Ana
name: Sosa-Ochoa, Wilfredo
name: Fontecha, Gustavo
Publisher: name: Figshare
Year: 2015
Subjects: subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology

description: STROBE statement.
Surimyia rolanderi Reemer
Creators: name: Carvalho-Filho, Fernando Da Silva
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Syrphidae
Surimyia
Surimyia rolanderi

description: Surimyia rolanderi Reemer (Figs 10–11)
Material examined. Brazil, Pará, Serra Norte, Fofoca (municipality of Parauapebas), armadilha suspensa [= suspended trap], 28–31.X.1983, leg. F.F. Ramos [collector] (1 f#, coll. MPEG).
Comments. This is the first record of S. rolanderi from the Brazilian Amazon and outside of Surinam.
description: Published as part of Carvalho-Filho, Fernando Da Silva, 2014, Description of new species of Surimyia Reemer and Carreramyia Doesburg (Diptera: Syrphidae) from the Brazilian Amazon, pp. 79-87 in Zootaxa 3887 (1) on page 83, DOI: 10.11646/zootaxa.3887.1.5, http://zenodo.org/record/287495
MOESM1 of Engineering Yarrowia lipolytica to produce biodiesel from raw starch
Creators: name: Ledesma-Amaro, Rodrigo
name: Dulermo, Thierry
name: Nicaud, Jean
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Additional file 1: Table S1. Optimized genes used in this work. Targeting sequences are shown: Pre region underlined and X-Ala sequences in bold.
IX-XII ASRLARDA MAMLAKATIMIZ HUDUDIDA RO'Y BERGAN MADANIY UYG'ONISH, BUYUK ALLOMALARNING JAHON SIVILIZATSIYASIGA QO'SHGAN HISSASI
Creators: name: Abdufattayeva, Gulzoda
name: Abfuxoliqova, Muxlisa
Publisher: name: Zenodo
Year: 2024

description: Ushbu tezis IX-XII asrlarda Markaziy Osiyoda yuzaga kelgan madaniy uyg‘onish va ilm-fan rivojlanishi haqida. Tezisda buyuk allomalar, ularning ilmiy merosi, va ilmiy markazlarning ahamiyati ko‘rsatilgan. Shuningdek, ilm-fan va madaniyatning jahon sivilizatsiyasiga qo‘shgan hissasi hamda Renessansning boshlanishiga ta’sirita’riflanadi.
Additional file 5 of Identification of in vitro and in vivo disconnects using transcriptomic data
Creators: name: Otava, Martin
name: Shkedy, Ziv
name: Talloen, Willem
name: Verheyen, Geert
name: Adetayo Kasim
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary appendix. Additional figures on gene expression profiles. Simulation study based validation of the methodology.
Surimyia
Creators: name: Carvalho-Filho, Fernando Da Silva
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Syrphidae
Surimyia

description: Key to species of Surimyia
1 Face yellow, without brown marks (Fig. 11); antenna shorter than eye height (Figs 10, 11); hypandrium elongated and curved. ….................................................................................................. 2
- Face yellow with a median brown mark (Figs 2, 3); antenna about as long as eye height (Figs 2, 3); hypandrium almost triangular, not curved (Figs 8, 9) (Brazilian Amazon)................................................. S. reemeri sp. n.
2 Scape shorter than pedicel and blasoflagellomere together; anepimeron with three setae; ocellar triangle in frontal view hardly elevated (Surinam).................................................................. S. minutula (Doesburg)
- Scape approximately as long as pedicel and blasoflagellomere together; anepimeron with eight to ten setae; ocellar triangle in frontal view clearly elevated relative to vertex (Surinam, Brazil)................................. S. rolanderi Reemer
description: Published as part of Carvalho-Filho, Fernando Da Silva, 2014, Description of new species of Surimyia Reemer and Carreramyia Doesburg (Diptera: Syrphidae) from the Brazilian Amazon, pp. 79-87 in Zootaxa 3887 (1) on page 84, DOI: 10.11646/zootaxa.3887.1.5, http://zenodo.org/record/287495
Transition Metal-Mediated Functionalization of White Phosphorus
Creators: name: Hoidn, Christian M.
name: Scott, Daniel J.
name: Wolf, Robert
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: COORDINATION SPHERE; TRIPLE-BOND; TERMINAL PHOSPHIDE; P-4 ACTIVATION; COMPLEXES; LIGANDS; IRON; REACTIVITY; NIOBIUM; TRANSFORMATION; coordination compounds; P ligands; radicals; transition metals; white phosphorus
subject: 540 Chemie

description: Recently there has been great interest in the reactivity of transition-metal (TM) centers towards white phosphorus (P-4). This has ultimately been motivated by a desire to find TM-mediated alternatives to the current industrial routes used to transform P-4 into myriad useful P-containing products, which are typically indirect, wasteful, and highly hazardous. Such a TM-mediated process can be divided into two steps: activation of P-4 to generate a polyphosphorus complex TM-P-n, and subsequent functionalization of this complex to release the desired phosphorus-containing product. The former step has by now become well established, allowing the isolation of many different TM-P-n products. In contrast, productive functionalization of these complexes has proven extremely challenging and has been achieved only in a relative handful of cases. In this review we provide a comprehensive summary of successful TM-P-n functionalization reactions, where TM-P-n must be accessible by reaction of a TM precursor with P-4. We hope that this will provide a useful resource for continuing efforts that are working towards this highly challenging goal of modern synthetic chemistry.
Additional file 1: of Subcellular dissemination of prothymosin alpha at normal physiology: immunohistochemical vis-a-vis western blotting perspective
Creators: name: Kijogi, Caroline
name: Khayeka-Wandabwa, Christopher
name: Sasaki, Keita
name: Tanaka, Yoshimasa
name: Kurosu, Hiroshi
name: Matsunaga, Hayato
name: Ueda, Hiroshi
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology
subject: Cardiology

description: Densitometric quantification of the western blot bands of PTMA expression in the selected brain regions. Each value is the Mean ± SD of at least three independent experiments. Arbitrary units were obtained by normalizing the signal to the internal control (values shown are PTMA signal/GAPDH signal). (DOCX 65 kb)
Additional file 1: of Short telomere length and its correlation with gene mutations in myelodysplastic syndrome
Creators: name: Hwang, Sang
name: Kim, Seon
name: Kim, Jung
name: Hee-Sue Park
name: Park, Si
name: Kyongok Im
name: Kwantae Kim
name: Kim, Sung-Min
name: Lee, Dong
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Supplementary method. Figure S1. Correlation of gene categories and cytogenetic abnormalities. Table S1. Genes included in the target sequencing and its gene categories. Table S2. Telomere lengths according to WHO categories or IPSS subgroups. Table S3. Telomere lengths according to laboratory results. Table S4. Telomere lengths according to mutations in gene groups. (DOC 803 kb)
MOESM1 of Production of l(+)-lactic acid from acid pretreated sugarcane bagasse using Bacillus coagulans DSM2314 in a simultaneous saccharification and fermentation strategy
Creators: name: Pol, Edwin
name: Eggink, Gerrit
name: Weusthuis, Ruud
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology
subject: Computational Biology

description: Additional file 1: Fig S1. Sugar concentration over time during fermentation. Simultaneous Saccharification and Fermentation (SSF) experiments performed using 200 g/l acid pretreated bagasse DW and 10.5-15.8 FPU/g DW bagasse GC220 enzyme cocktail in pH controlled fermentations with a start volume of 1 litre. As inoculum, either furfural containing or reference preculture was used. The bagasse was either added in one batch or in two stages. Glucose was measured using HPLC. The following experiments were performed: ●: batch SSF solubilised with liquid fraction, inoculated with reference preculture, ■: batch SSF solubilised with liquid fraction, inoculated with furfural preculture, ▼: batch SSF solubilised with water, inoculated with furfural preculture (15% V/DW enzymes), ◆: two-stage SSF solubilised with water, inoculated with furfural preculture.
Cationic liposomes for generic signal amplification strategies in bioassays
Creators: name: Baeumner, Antje J.
name: Hofmann, Carola
name: Kaiser, Barbara
name: Maerkl, Susanne
name: Duerkop, Axel
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: CHOLESTEROL; VESICLES; LIPIDS; LABEL; Liposomes; Electrostatic interaction; Bioanalysis; Bacteria; E. coli
subject: 540 Chemie
subject: 570 Biowissenschaften, Biologie

description: Liposomes have been widely applied in bioanalytical assays. Most liposomes used bare negative charges to prevent non-specific binding and increase colloidal stability. Here, in contrast, highly stable, positively charged liposomes entrapping the fluorescent dye sulforhodamine B (SRB) were developed to serve as a secondary, non-specific label, and signal amplification tool in bioanalytical systems by exploiting their electrostatic interaction with negatively charged vesicles, surfaces, and microorganisms. The cationic liposomes were optimized for long-term stability (> 5 months) and high dye entrapment yield. Their capability as secondary, non-specific labels was first successfully proven through electrostatic interactions of cationic and anionic liposomes using dynamic light scattering, and then in a bioassay with fluorescence detection leading to an enhancement factor of 8.5 without any additional surface blocking steps. Moreover, the cationic liposomes bound efficiently to anionic magnetic beads were stable throughout magnetic separation procedures and could hence serve directly as labels in magnetic separation and purification strategies. Finally, the electrostatic interaction was exploited for the direct, simple, non-specific labeling of gram-negative bacteria. Isolated Escherichia coli cells were chosen as models and direct detection was demonstrated via fluorescent and chemiluminescent liposomes. Thus, these cationic liposomes can be used as generic labels for the development of ultrasensitive bioassays based on electrostatic interaction without the need for additional expensive recognition units like antibodies, where desired specificity is already afforded through other strategies.
Ancistrosyllis McIntosh 1878
Creators: name: Plathong, Sakanan
name: Plathong, Jintana
name: Dean, Harlan K.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Polychaeta
Phyllodocida
Pilargidae
Ancistrosyllis

description: Genus Ancistrosyllis McIntosh, 1878
Diagnosis (after Glasby & Salazar-Vallejo 2022). Pilargids with body depressed, integument papillose to verrucose, present on both segmental and nonsegmental regions. Zero to three antennae. Palps unfused, biarticulated, palpostyle minute. Paired ventrolateral palpal papillae present. Pharynx distally with terminal papillae (or absent); proximally smooth or, rarely, with denticles. Two pairs of tentacular cirri. Dorsal and ventral cirri digitate to lobate. Notochaetae are hooks, starting from chaetigers 3 to 13 and continuing throughout body. Neurochaetae smooth, or spinulose capillaries, often with bidentate tips. Free living in sediments from intertidal to deep sea, or commensal with other invertebrates.
description: Published as part of Plathong, Sakanan, Plathong, Jintana & Dean, Harlan K., 2022, Two new species of Ancistrosyllis McIntosh, 1878 (Annelida: Pilargidae) from the Gulf of Thailand, Western Pacific, pp. 195-210 in Zootaxa 5128 (2) on page 200, DOI: 10.11646/zootaxa.5128.2.2, http://zenodo.org/record/6479730
Additional file 2: of Subcellular dissemination of prothymosin alpha at normal physiology: immunohistochemical vis-a-vis western blotting perspective
Creators: name: Kijogi, Caroline
name: Khayeka-Wandabwa, Christopher
name: Sasaki, Keita
name: Tanaka, Yoshimasa
name: Kurosu, Hiroshi
name: Matsunaga, Hayato
name: Ueda, Hiroshi
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: Computational Biology
subject: Cardiology

description: Densitometric quantification of the western blot bands of PTMA expression across peripheral tissues. Each value is the Mean ± SD of at least three independent experiments. Arbitrary units were obtained by normalizing the signal to the internal control (values shown are PTMA signal/GAPDH signal). (DOCX 60 kb)
Additional file 1: of Patientsâ   willingness to participate in clinical trials and their views on aspects of cancer research: results of a prospective patient survey
Creators: name: Sing Moorcraft
name: Marriott, Cheryl
name: Peckitt, Clare
name: Cunningham, David
name: Chau, Ian
name: Naureen Starling
name: Watkins, David
name: Rao, Sheela
Publisher: name: Figshare
Year: 2016
Subjects: Medicine
Science Policy

description: Questionnaire A. Description: questionnaire given to patients who consented to a clinical trial. (DOC 166 kb)
Additional file 3: Table S1. of Intrinsic protein disorder in histone lysine methylation
Creators: name: Lazar, Tamas
name: Schad, Eva
name: Szabo, Beata
name: Horvath, Tamas
name: Meszaros, Attila
name: Tompa, Peter
name: Tantos, Agnes
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Sequence and disorder conservation of six human HKMTs and CBP and BRCA1 based on the multiple sequence alignment of vertebrate orthologs. (DOCX 55 kb)
Additional file 2: of Patientsâ   willingness to participate in clinical trials and their views on aspects of cancer research: results of a prospective patient survey
Creators: name: Sing Moorcraft
name: Marriott, Cheryl
name: Peckitt, Clare
name: Cunningham, David
name: Chau, Ian
name: Naureen Starling
name: Watkins, David
name: Rao, Sheela
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Science Policy
subject: 60506 Virology
subject: FOS: Biological sciences

description: Questionnaire B. Description: questionnaire given to patients who declined a clinical trial. (DOC 156 kb)
Labarrus lividus Olivier 1789
Creators: name: Minor, Pablo
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy

description: Distribution: Mexico (across the country, except Campeche and Colima); Subcosmopolitan. 90 Labarrus lividus (Olivier, 1789)
Distribution: Mexico (?); Subcosmopolitan.
description: Published as part of Minor, Pablo, 2017, New state records and updated checklist of Aphodiini and Eupariini (Coleoptera: Scarabaeidae: Aphodiinae) from Mexico, pp. 493-514 in Zootaxa 4244 (4) on page 507, DOI: 10.11646/zootaxa.4244.4.3, http://zenodo.org/record/437241
LIBER LAG 2024 - Reinventing the laboratory library: the Humathèque Condorcet, a new research library for new uses.
Creators: name: Groudiev, Stéphanie
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Architecture
subject: FOS: Civil engineering
subject: Library Architecture

description: Reinventingthe laboratorylibrary: the Humathèque Condorcet, a new researchlibraryfor new uses.

Stéphanie Groudiev, director,

Humathèque Condorcet, France
Additional file 11. of Formation of the germ-disc in spider embryos by a condensation-like mechanism
Creators: name: Pechmann, Matthias
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Supplementary figures and methods; contains the Figures S1-S5. (PDF 10478 kb)
Versatile Visible-Light-Driven Synthesis of Asymmetrical Phosphines and Phosphonium Salts
Creators: name: Arockiam, Percia-Beatrice
name: Lennert, Ulrich
name: Graf, Christina
name: Rothfelder, Robin
name: Scott, Daniel J.
name: Fischer, Tillmann G.
name: Zeitler, Kirsten
name: Wolf, Robert
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: CATALYZED SYNTHESIS; INTERMOLECULAR HYDROPHOSPHINATION; IONIC LIQUIDS; EASY ACCESS; ARYL; COMPLEXES; CONVENIENT; ALKENES; LIGAND; ALKYL; alkylation; arylation; phosphane; phosphorus; photocatalysis
subject: 540 Chemie

description: Asymmetrically substituted tertiary phosphines and quaternary phosphonium salts are used extensively in applications throughout industry and academia. Despite their significance, classical methods to synthesize such compounds often demand either harsh reaction conditions, prefunctionalization of starting materials, highly sensitive organometallic reagents, or expensive transition-metal catalysts. Mild, practical methods thus remain elusive, despite being of great current interest. Herein, we describe a visible-light-driven method to form these products from secondary and primary phosphines. Using an inexpensive organic photocatalyst and blue-light irradiation, arylphosphines can be both alkylated and arylated using commercially available organohalides. In addition, the same organocatalyst can be used to transform white phosphorus (P-4) directly into symmetrical aryl phosphines and phosphonium salts in a single reaction step, which has previously only been possible using precious metal catalysis.
New Business Marketing for 2025; Maximizing Your Content Marketing
Creators: name: Mirmiran, Seyed Farzad
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Marketing/methods
subject: Marketing Trends
subject: Business Marketing
subject: Content Writing
subject: Small Business
subject: Business Writing

description: Summary

Content marketing is one of the most effective ways for businesses to attract, engage, and convert potential customers. Through the creation and distribution of valuable, relevant content such as blog posts, white papers, case studies, and videos, businesses can establish their brand as a trusted authority in their industry. For CEOs, leveraging business writing skills to craft content that educates, informs, and persuades is critical to driving conversions. This article explores how to maximize the effectiveness of content marketing, from understanding its strategic role in the sales funnel to employing persuasive writing techniques that lead to greater engagement and action. By optimizing content marketing efforts, businesses can increase traffic, enhance brand authority, and ultimately drive sales.
Magnetosomes for bioassays by merging fluorescent liposomes and magnetic nanoparticles: encapsulation and bilayer insertion strategies
Creators: name: Baeumner, Antje J.
name: Hermann, Cornelia A.
name: Hofmann, Carola
name: Duerkop, Axel
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: IMMUNOMAGNETIC SEPARATION; DNA; Magnetic nanoparticles; Fluorescent liposomes; DNA sandwich hybridization assay; Magnetosomes; Signal enhancement
subject: 540 Chemie
subject: 570 Biowissenschaften, Biologie

description: Magnetized liposome (magnetosomes) labels can overcome diffusion limitations in bioassays through fast and easy magnetic attraction. Our aim therefore was to advance the understanding of factors influencing their synthesis focusing on encapsulation strategies and synthesis parameters. Magnetosome synthesis is governed by the surface chemistry and the size of the magnetic nanoparticles used. We therefore studied the two possible magnetic labelling strategies, which are the incorporation of small, hydrophobic magnetic nanoparticles (MNPs) into the bilayer core (b-liposomes) and the entrapment of larger hydrophilic MNPs into the liposomes' inner cavity (i-liposomes). Furthermore, they were optimized and compared for application in a DNA bioassay. The major obstacles observed for each of these strategies were on the one hand the need for highly concentrated hydrophilic MNPs, which is limited by their colloidal stability and costs, and on the other hand the balancing of magnetic strength vs. size for the hydrophobic MNPs. In the end, both strategies yielded magnetosomes with good performance, which improved the limit of detection of a non-magnetic DNA hybridization assay by a factor of 3-8-fold. Here, i-liposomes with a magnetization yield of 5% could be further improved through a simple magnetic pre-concentration step and provided in the end an 8-fold improvement of the limit of detection compared with non-magnetic conditions. In the case of b-liposomes, Janus-like particles were generated during the synthesis and yielded a fraction of 15% magnetosomes directly. Surprisingly, further magnetic pre-concentration did not improve their bioassay performance. It is thus assumed that magnetosomes pull normal liposomes through the magnetic field towards the surface and the presence of more magnetosomes is not needed. The overall stability of magnetosomes during storage and magnetic action, their superior bioassay performance, and their adaptability towards size and surface chemistry of MNPs makes them highly valuable signal enhancers in bioanalysis and potential tools for bioseparations. Graphical abstract
Additional file 4: Table S2. of Intrinsic protein disorder in histone lysine methylation
Creators: name: Lazar, Tamas
name: Schad, Eva
name: Szabo, Beata
name: Horvath, Tamas
name: Meszaros, Attila
name: Tompa, Peter
name: Tantos, Agnes
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology

description: Human HKMTs with disorder rate (IUPred) higher than 50Â %. Disorder %: the total proportion of amino acids with an IUPred score above 0.5. Longest IDR: the longest region with all amino acids having IUPred score above 0.5. Function: catalytic activities of the HKMTs. ELM motifs: Eukaryotic Linear Motifs collected from the ELM database. Experimentally verified motifs are typed with normal characters and predicted (eâ
Exploration, Distributed Attention, and Development of Category Learning
Creators: name: Wan, Qianqian
name: Sloutsky, Vladimir
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Social and Behavioral Sciences

description: Category learning is a crucial aspect of cognition that involves organizing entities into equivalence classes. Whereas adults tend to focus on category-relevant features, young children often distribute attention between relevant and irrelevant ones. The reasons for children's distributed attention are not fully understood. In two category-learning experiments with children aged 4, 5, and 6 and adults (N = 201), we examined potential drivers of distributed attention, including (1) immature filtering of distractors and (2) the general tendency for exploration or broad information sampling. By eliminating distracter competition, we reduced filtering demands. Despite identifying the features critical for accurate categorization, children, regardless of their categorization performance, continued sampling more information than was necessary. These results indicate that the tendency to sample information extensively contributes to distributed attention in young children. We identify candidate drivers of this tendency that need to be examined in future research.