cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Voice response applications for a hospital computer system
Creators: name: Price, Walter Gary
Publisher: name: University of Utah
Year: 2012
Subjects: Vocoder
Biomedical Research

description: Clinical computer applications are becoming increasingly important in health care delivery.  The expense of video terminals limits access to the power of the computer.  Voice response, using a common telephone as a computer terminal, increases accessibility and is shown to be a workable means of communication in a hospital environment.  Current methods of processing speech for voice response are reviewed.  Analog, digital, and parametric methods are compared and evaluated for use in a hospital environment.  Great importance is given to the need for economy, large vocabulary with low storage requirement, flexibility of application, and compatibility with the existing computer system at LDS Hospital.  Reasons for choosing Infinitely-Clipped speech are presented.  Investigations into methods of enhancing the intelligibility of Infinitely-Clipped Speech are reviewed.  Peripheral hardware, constructed to code the reproduce clipped speech in real time outside the computer, is described in detail.  A coding scheme, which preserves intelligibility while reducing data storage requirements, is presented.  VOTRAX, a commercial speech synthesizer, is compared to the Infinitely-Clipped Speech system.  Software systems to store and retrieved coded equivalents of spoken words are described.  Distinct dictionary constructions are presented to meet the requirements of the different synthesizers.  Provisions were made to allow users to control repetitions of data input requests and output messages, in addition to error correction and input data verification procedures.  Software and hardware were designed to be compatible with existing video display terminal communication protocol.  Blood Gas Test Requests, Blood Gas Analysis Reports and Patient Problem List Review applications were adapted from existing video terminal implementations for voice response trials.  The selection of these applications was based on the large vocabulary required, the limited input and output message length use, and the need for infrequent use from diverse locations within or outside the hospital.  Communication of Blood Gas Requests and Reports expanded from one to eight nursing divisions.  Intelligibility tests were performed with participants from the eight nursing divisions in their actual working environments.  Results for both ICS and VOTRAX processing approached 90% for isolated words taken from the Blood Gas applications.  The importance of familiarization with the peculiar accents of the systems is noted.  Use and acceptance of voice response in the chosen applications is discussed.  Future applications are suggested.
Coilodes castaneus Westwood 1846
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Hybosoridae
Coilodes
Coilodes castaneus

description: Coilodes castaneus Westwood, 1846
Coilodes castaneus Westwood 1846: 165 (Colombia)
Distribution. French Guiana: See note. Brazil (NA): Havranek 1988: 32 (as C. castanea) (NA). Venezuela (EO): Young 1983: 247; Havranek 1988: 32 (as C. castanea) (EO). Other: Westwood 1846: 165 (Colombia); Arrow 1912: 37 (Colombia, Nicaragua - as Coelodes [sic] castanea); Blackwelder 1944: 217 (Colombia, Costa Rica, Nicaragua - as C. castanea); Young 1983: 247 (Colombia, Costa Rica, Ecuador, Nicaragua, Panama); Allsopp 1984: 106 (Colombia, Costa Rica, Nicaragua); Havranek 1988: 32 (Colombia, Costa Rica, Ecuador, Panama - as C. castanea); Ocampo and Ballerio 2006: 191 (Colombia, Costa Rica, Nicaragua).
Note. An unidentified species of Coilodes is recorded for French Guiana in Feer (2000: 33) (as Coelodes [sic] sp.), Moragues (2010c: 77) and Brûlé et al. (2011a: 185, 2014: 178). This may or may not be C. castaneus, which is the only species within the genus known to occur in the research area. The NZCS also has an unidentified specimen from French Guiana. The actual presence of C. castaneus in the research area remains to be confirmed.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 22, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 20933.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.11.1961, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 20862.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.09.1961, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Paisajes culturales: sus usos y apreciaciones
Creators: name: Macías Madero, Adriana
Publisher: name: Revista Chicomoztoc
Year: 2022

description: Resumen El objetivo principal de este trabajo es dar una visión general de las transformaciones sociales y geográficas que se han dado en la región de Tierra Caliente, a través de la implementación de diversas actividades económicas. Con el fin de poder apreciar mejor dichos cambios se hace un recuento de la historia de las poblaciones desde época indígena hasta la actual, haciendo una conjunción del estudio histórico (lo que se dice) y del paisaje (lo que se ve) (Arnold, 2000: 42; Brunet, 1982: 487). La observación de los elementos que quedan registrados en el entorno es la base que nos permitirá descubrir el pasado y entender el presente de un grupo (Brunet, 1982: 489; Sauer, 1982: 353), es por eso que en este trabajo se mencionan algunas de las características geográficas de algunas regiones de Tierra Caliente, especialmente el municipio de Buena Vista, Michoacán. Palabras clave: modos de vida, actividades económicas transformaciones sociales, geografía. Abstract The main objective of this work is to give an overview of the social and geographical transformations that have occurred in the Tierra Caliente region, through the implementation of various economic activities. In order to better appreciate these changes, a recount is made of the history of the populations from the indigenous era to the present, making a conjunction of the historical study (what is said) and the landscape (what is seen) (Arnold, 2000: 42; Brunet, 1982: 487). The observation of the elements that are recorded in the environment is the basis that will allow us to discover the past and understand the present of a group (Brunet, 1982: 489; Sauer, 1982: 353), that is why in this work we mention some of the geographical characteristics of some regions of Tierra Caliente, especially the municipality of Buena Vista, Michoacán.Key words: ways of life, economic activities, social transformations, geography
description: Revista Chicomoztoc, Vol. 4 Núm. 8 (2022): Revista Chicomoztoc. Vol. 4, No. 8, Julio - diciembre 2022
Attraction activities of W-STEM program implementing for the Universidad Tecnica del Norte team
Creators: name: Tobar, L. M.
name: Proaño, V.
name: Gámez, B.
name: Ramirez, C.
name: Caraguay, J.
name: Vasquez, C.
Publisher: name: Zenodo
Year: 2022
Subjects: Women, Science, CBHE, EU, gender, STEM, W-STEM, Latin-America

description: Currently there is a great movement to encourage women to choose careers related to the fields of science and technology, since, by different factors historically this gender has had very little representation in these areas of knowledge. In this poster, we present the main results of the activities related to UTN Attraction Campaigns during 2020 within W-STEM project context. It is important to underline that Internet connection was the biggest problem during COVID-19 pandemic to develop the attraction campaigns.
description: The European Commission support for the production of this publication does not constitute an endorsement of the contents which reflects the views only of the authors, and the Commission cannot be held responsible for any use which may be made of the information contained therein.
Chemical synthesis and biological evaluation of novel lysophospholipid analoguesg
Creators: name: Jiang, Guowei
Publisher: name: University of Utah
Year: 2012
Subjects: Synthesis
Lysophosphatidic Acid receptors

description: Phospholipids, including lysobisphosphatidic acid (LBPA) and lysophosphatidic acid (LPA), have been shown to mediate a variety of biological effect and are involved in various pathophysiological process, such as Niemann-Pick type C (NPC) disease, cancer, cardiovascular disease, and wound healing. Development of new metabolically-stabilized LBPA and LPA analogues will help determine the relationships between these lysophospholipids and their role in normal physiology and disease state.  In Chapter 2, a versatile, efficient and practical method for the preparation of enantiomerically-pure lysobisphosphatidic acid (LBPA), bisether analogues and phosphorothioate analogues of LBPA is described. The ether analogue of (S,S)-lysobisphosphatidic acid (LBPA) and its enantiomer were synthesized from a single enantiomer (S)-solketal by simply changing the sequence of deprotection steps.  In Chapters 3 and 4, a series of novel a-substituted methylene phosphonate analogues and phosphonothioate analogues of LPA were synthesized. Each a-substituted methylene phosphonate analogue contains a hydrolysis-resistant phosphonate mimic of the labile monophosphate of natural LPA. The pharmacological properties of these phosphono-LPA analogues were characterized in terms of LPA receptor subtype-specific agonist and antagonist activity. Most importantly, the a-bromomethylene and a-chloromethylene phosphonates showed pan-LPA receptor subtype antagonist activity. The a-bromomethylene phosphonates are the first reported antagonists for the LPA4 GPCR. Each of the a-substituted methylene phosphonates inhibited lysoPLD, with the Linsubstituted methylene phosphonate showing the most potent inhibition.
Sonnenfleckenzeichnung Nr. 20892.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.10.1961, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Dicraeodon Erichson 1847
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Hybosoridae
Dicraeodon

description: DICRAEODON Erichson, 1847
Dicraeodon Erichson 1847: 104
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 22, DOI: 10.5281/zenodo.3678492
Parental knowledge regarding immunizations
Creators: name: Brown, Susan
Publisher: name: University of Utah
Year: 2012
Subjects: Parents
Chid
Infant

description: The purpose of this research study was to examine whether or not educational information about immunizations was being provided to parents. This study also examined the knowledge level parents had about what diseases were covered by the immunizations and when the immunizations were due. This nonexperimental descriptive research design was accomplished through one-time, structured, self-report interviews in a community health center. Parents or caregivers of children between the ages of 4 months to 2 years, who had an appointment with a primary health care provider in the clinic, were interviewed. The parents in this study reported receiving helpful information about immunizations from two main sources: (a) the immunization schedule handout and (b) discussions with their health care provider. Of the 40 parents interviewed, 100% believed the immunization schedule handout was helpful or very helpful. Thirty-eight parents (95%) believed that the discussion they had with their health care provider was helpful or very helpful. Thirty-eight parents (95%) believed that the discussion they had with their health care provider was helpful or very helpful.  Thirty-seven parents (92.5%) believed the information currently being provided was sufficient for their needs. Only 2 parents (5%) stated completely the recommended time schedule for immunizations, including birth and 1 month old. None of the parents could identify all the immunizations recommended at 2 months, 4 months, 6 months, and 12 to 15 months. With the exception of the hepatitis series, 4 parents (10%) stated the specific immunizations recommended at 2 months, 4 months, 6 months, and 12 to 15 months. First, the results of this research study indicated that parents were provided with information about immunizations.  Second, the results of this study indicated that the knowledge parents had about specific details regarding immunizations was limited.  However, the parents perceived that the information provided and their knowledge about immunizations were sufficient to meet their health education needs.  The health care provider's perception of the amount of knowledge parents should have regarding immunizations may not be the same as what the parents believed they need to know.  For the parents in the study, their perception that their child was current on his or her immunizations was sufficient.
The metabolism of intravenous testosterone.
Creators: name: West, Charles Donald
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Metablism
subject: Biochemistry

description: The fate of testosterone administered intravenously in experimental animals has been investigated.  The injected testosterone diffused rapidly from the circulation into various tissues of the body, the highest concentrations being found in fat.  The testosterone was apparently not metabolized in the fatty tissues but was reabsorbed back into the circulation as it was removed by other structures.  Evidence in presented to indicate that the liver and kidney is probable site of such metabolism.  That other sites than liver and kidney might be involved in the metabolism of testosterone was indicated by studies in hepatectomized, nephrectomized animals in which less than 50% of the testosterone injected could be accounted for in a major proportion of the tissues.  The metabolism of testosterone in human serum albumin given intravenously to human subjects was studied.  In normal subjects an average of 74% of the injected testosterone was accounted for by an increased in urinary conjugated 17-ketosteroids during the post-injection period.  An average of 63% was excreted during the first 24 hours with the major part of this excretion occurring during the first two hours.  Following intravenous testosterone conjugated 17-ketosteroids were demonstrable in the plasmas.  Maximum plasma level was found at 20 minutes after administration.  The importance of the liver in the metabolism of testosterone was demonstrated by the lower concentrations of 17-ketosteroids in both the urine and plasma following administration of testosterone intravenously in a series of patients with liver disease.  More than on pathway of testosterone metabolism was indicated by the much lower proportion of the injected hormone which was recovered as excess 17-ketosteroids in the cirrhotic patients in spite of the rapid disappearance and minimal excretion of the original steroid.  After intravenous administration of testosterone to normal males the following steroids were isolated from the urine and identified:  etiocholanol-3alpha-one-17, androsterone, etiocholanediol 3alpha, 17alpha and 3delta,5-androstadienone-17.  It was further demonstrated that the androsterone and eitocholanolone which made up the greater part of the 17-ketosteroids in the urine were conjugated with glucuronic acid.  No significant amounts of 3beta-hydroxysteroids were found in the ketonic fraction.
Recent Update on MoSDeF - the Molecular Simulation Designs Framework
Creators: name: Cummings, Peter
name: McCabe, Clare
name: Ledeczi, Akos
name: Iacovella, Cristopher
name: Glotzer, Sharon
name: Jankowski, Eric
name: Maginn, Edward
name: Seipmann, J. Ilja
name: Palmer, Jeremy
name: Jayaraman, Arthi
name: Potoff, Jeffrey
Publisher: name: Zenodo
Year: 2022

description: A poster describing the Molecular Simulation Design Framework, software tools that are collaboratively developed to support transparent, reproducible, usable, and extensible molecular simulations.
Aphodiini Leach 1815
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae

description: APHODIINI Leach, 1815
Synopsis. Dellacasa et al. 2001a (genera)
Catalogue. Skelley et al. 2007 (Mexico, Central and South America)
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 22, DOI: 10.5281/zenodo.3678492
Nuclear magnetic resonance studies of an intrinsically disordered protein: the N protein of bacteriophage lambda
Creators: name: Bhattacharje, Gourab
Publisher: name: University of Utah
Year: 2015
Subjects: Amphipathic alpha-helix
Antitermination apparatus
Bacteriophage Lambda N
Conformational selection
Intrinsically disordered protein (IDP)
Transient secondary structure

description: Nuclear magnetic resonance (NMR) spectroscopy was employed to characterize structural and dynamic properties of bacteriophage ƛN protein (ƛN). ƛN is an intrinsically disordered protein (IDP) that interacts with multiple partners to prevent termination in the phage ƛ-Escherichia coli transcription apparatus. Limited dispersion in the 1H dimension of the 1H-15N heteronuclear correlation spectra confirmed the extensively disordered nature of ƛN. Resonance assignments were made for the amide-15N, amide-1H, 13Cα and 13Cβ nuclei of more than 90% of the nonproline residues at pH 7 and 5.5, which were subsequently used to calculate secondary structure propensities. Residues 2-7 and 55-75 showed propensities to form α-helical structures, whereas the residues 34-47 and 95-107 showed propensities to form extended structures. Previous studies have shown that residues 1-22 of ƛN adopt a helical structure when bound to a site in the RNA transcript (boxB) and residues 34-47 form an extended structure to interact with E. coli host transcription factor NusA protein. We have discovered that the residues 55-75 of ƛN protein, hitherto uncharacterized, have propensities to form transient helical secondary structures. This putative transient helical region spanning residues 55-75 is amphipathic and may form coiled-coil structures, which further suggests a possible structural or functional role of this segment in the antitermination apparatus. To characterize the backbone dynamics of ƛN, 15N longitudinal relaxation rates (R1), transverse relaxation rates (R2), and steady-state 15N-1H nuclear Overhauser effects were measured. Significantly elevated transverse relaxation rates (R2) for the amide groups of residues 55-75 indicated slow conformational exchange in the ƛs-ms timescale, consistent with a transient secondary structure in this segment of ƛN. Faster amide-bond motions were analyzed by mapping reduced spectral density functions, derived from the 15N relaxation parameters, which further revealed backbone motions on two or more timescales, as expected for a nonglobular disordered protein. The results of this NMR study suggest the presence of previously unknown functional domains of ƛN protein, which may enhance our understanding of the phage ƛ-Escherichia coli antitermination apparatus and allow further investigations of the binding mechanisms of IDPs with their interacting partners.
Sonnenfleckenzeichnung Nr. 20900.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.10.1961, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Dicraeodon basalis
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Hybosoridae
Dicraeodon
Dicraeodon basalis

description: Dicraeodon basalis (Westwood, 1846)
Chaetodus? basalis Westwood 1846: 166 (French Guiana)
Distribution. Suriname: MHCN - NEW COUNTRY RECORD (Suriname, Sipaliwini, Arapahu Resort, (3°27′N, 57°37.5′W). 14/ 16-II-2011. A. J. Hielkema. Flying on sweaty clothes from 07.45–09.30h.); NZCS. French Guiana: Westwood 1846: 166 (as Chaetodus? basalis); Allsop 1984: 107; Ocampo and Ballerio 2006: 191. “Guianas”: Arrow 1912: 39; Blackwelder 1944: 217 (as Dicraeodon basale).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 22, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 20911.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.11.1961, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 20932.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.11.1961, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Adenosine 3',5'-monophosphate in highly purified and mixed primary cultures of neurons and non-neuronal cells from embryonic chick sympathetic ganglia
Creators: name: Wallace, Lane Jackson
Publisher: name: University of Utah
Year: 2012
Subjects: Pharmacology
Cells
Cultured

description: Primary cultures containing  99% neurons,  99% non-neuronal cell (glia), or both cell types prepared from the sympathetic ganglia of 12-day chick embryos.  Levels of cyclic AMP in the non-neuronal cells (~ 14 pmoles per mg protein) were approximately three-fold higher than levels in the neurons (~ 4 pmoles per mg protein).  Mixed cultures had concentrations of cyclic AMP which fell between the values measured for pure neuronal and pure non-neuronal cultures.  The measured cyclic AMP values of mixed cultures were indistinguishable from values predicted by summing the expected contributions of the neurons and non-neuronal cells.  Thus, contact between the neurons and non-neuronal cells in these mixed cultures did not appear to alter the level of cyclic AMP in either cell type.  Neuronal-glial interactions, such as the specific neuronal stimulation of non-neuronal cell proliferation, occurred independently of any changes in the level of cyclic AMP in the mixed cultures.  Cell density was varied in both pure and mixed cultures, and both cyclic AMP concentrations and amounts of 3H-thymidine incorporation into DNA were measured.  The cyclic AMP content of the non-neuronal cells varied inversely with cell density.  3H-Thymidine incorporation was independed of cell density in both neuronal and non-neuronal cultures.  Parallel density-dependent decreases in cyclic AMP concentration and 3H-thymidine incorporation were observed in mixed cultures as cell density was increased.  The data suggest that there is no relationship between changes in rate of non-neuronal cell proliferation and cyclic AMP levels in these cultures.  The effects of some putative neurotransmitters, analogs of transmitters, and adenosine on levels of cyclic AMP were determined in primary neuronal, non-neural, and mixed cultures of embryonic chick sympathetic ganglion cells.  Adenosine increased the level of cyclic AMP in the non-neuronal cells but had no effect on levels in either neuronal or mixed cultures.  Norepinephrine increased the level of cyclic AMP in neurons, had no effect on the non-neuronal levels, and decreased the cyclic nucleotide content of mixed cultures.  Dopamine, isoproterenol, and pilocarpine all caused a reduction in the cyclic AMP content of mixed cultures but had no effect on levels of either neurons on non-neuronal cells.  The measured cyclic AMP levels of norepinephrine- and isoproterenol-treated mixed cultures were significantly lower than the values predicted by summing the expected individual contributions of the neurons and the non-neuronal cells.  Thus, cells in mixed cultures sometimes responded differently from cells in pure cultures.
The Analysis of nonanalytical flow phenomena in magnetic resonance imaging using a finite difference method
Creators: name: Yuan, Chun
Publisher: name: University of Utah
Year: 2012
Subjects: Magnetic Resonance Spectroscopy
Pulsatile Flow
Stereotaxic Techniques
Thrombosis

description: In magnetic resonance (MR) imaging, moving spins have a significant effect on the received signal, which is seen, depending upon the pulse sequence utilized, as a modulation in signal intensity and/or phase relative to that of stationary spins. This can be used as an advantage to image vessels by using pulse sequences with timing parameters for radiofrequency (RF) and magnetic gradient wave forms that enhance the signal from flowing spins.  However, clinical MR images show this seemingly significant advantage is a disadvantage in the presence of pulsatile flow which causes variations in signal strengths and phases that result in image artifacts.  The artifacts vary with flow pattern, flow velocity, pulse flip angle, and imaging pulse sequence.  An in-depth study into quantifying the effect of flowing spins on image quality has not been done due in part to the difficulty to quantify the amplitude and phase modulation during RF excitation since solutions to the Bloch equations cannot be obtained analytically.   This dissertation studies flow problems in MR imaging that cannot be analyzed by analytically solving Bloch equations but require obtaining solutions through numerical methods. In particular, the study focuses on non-analytical flow phenomena experienced by spins flowing during time varying RF pulses. A finite difference method was derived for solving the Bloch equations and a computer simulation program was developed to simulate two-dimensional Fourier transform MR imaging. The combination of the finite difference method and the computer simulation program was used to analyze the degree to which variations in flow induced phase shifts and time-of-flight signal amplitude cause flow artifacts in MR imaging.  One-dimensional and two-dimensional flow was studied for slice-selective 90°, 90°-180° hyperbolic scent RF pulse and was shown to be a nonlinear function of spin velocity and flip angle.  Flow artifacts were simulated for one-dimensional pulsatile flow and an effective compensation scheme was developed to correct for flow induced phase shifts.  Also, a theoretical model was developed to predict time-of flight signal amplitude variations and a technique was developed to correct the image artifacts that results from these variations.  The study of one-dimensional flow was extended to a study to two-dimensional flow around a stenotic lesion.  The magnetic resonance signal amplitude and phase was spatially mapped across the two-dimensional flow vector field through vertical flow regions and differences in signal amplitude and phase between one- and two-dimensional flows were observed.  Based upon this work significant progress has been made in quantifying and simulating MR imaging of flow in the cardiovascular systems.
Sonnenfleckenzeichnung Nr. 20876.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.09.1961, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Blackburneus A. Schmidt 1913
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Aphodiidae
Blackburneus

description: BLACKBURNEUS A. Schmidt, 1913
Aphodius (Blackburneus) A. Schmidt 1913: 137
Synopsis. Dellacasa et al. 2011 (New World)
Note. According to Dellacasa et al. (2001a: 102), Blackburneus may need to be reduced to include only Neotropical species.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 22, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.07.1961, erstellt von Metin Hotinli an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
Cellular and genetic analysis of pharyngeal morphogenesis in Caenorhabditis elegans
Creators: name: Portereiko, Michael F.
Publisher: name: University of Utah
Year: 2012
Subjects: Pharyngeal Cells
Cytokinesis Defects
Pharyngeal Morphogenesis

description: During development of the pharynx in the nematode Caenorhabiditis elegans, pharyngeal precursor cells cluster together to form a primordium that subsequently undergoes a program of differentiation and morphogenesis to form a linear digestive tube. I combined three experimental approaches to study how the pharyngeal primordium becomes a tube at the cellular and genetic levels. First, I studied the behaviors of pharyngeal and nonpharyngeal cells required for tube formation. Second, I screened a deletion library for genetic loci required for pharyngeal morphogenesis. Lastly, I performed a genetic screen for pharyngeal tubulogenesis mutants. I used time-lapse videomicroscopy and GFP reporter constructs to follow the behavior of the pharyngeal precursors during pharyngeal extension, the process whereby the pharyngeal primordium attaches to the buccal cavity, or mouth of the worm. Pharyngeal extension can be loosely divided into three stages (i) reorganization of cellular polarity within pharyngeal cells (specifically the pharyngeal epithelial precursors), (ii) formation of an epithelium that mechanically couples the pharyngeal cells to arcade cells in the nascent buccal cavity, and (iii) an apparent contraction that shifts the buccal cavity posteriorly and the pharynx anteriorly. Using Nomarski DIC microscopy and immunostaining, we have classified sixteen deficiencies into two groups that affect pharyngeal development. The first group of deficiencies gives rise to a pharynx primordium that fails to differentiate. The second group generates terminal embryos with specific defects in pharyngeal morphogenesis. One subset of this group produces small and/or unattached pharynges. A second subset of this group of deficiencies produces a pharyngeal lumen that branches at a reproducible location along the pharyngeal axis. I performed a genetic screen for mutants that arrest with a p&barbelow;harynx un attached (Pun) phenotype at the L1 larval stage. I recovered 13 mutants from an ENU mutagenesis of 2838 haploid genomes. One mutant that I found in the screen is an allele of the mitotic kinesin like protein 1 (MKLP1) ortholog in C. elegans, ZEN-4. MKLP1 orthologs have been implicated in cytokinesis. I have shown that the pharyngeal morphogenesis defect observed in our newly discovered mutant allele of zen-4 is not due to cytokinesis defects, but rather it appears to specifically affect epithelialization.
Nurse-midwifery practice: a descriptive study of prenatal care.
Creators: name: Lehrman, Elaine Joyce
Publisher: name: University of Utah
Year: 2012
Subjects: Prenatal Care
Demographic Data

description: The research investigated the components of prenatal care provided by certified nurse-midwives, with the purpose of identifying the components and describing their incorporation into nurse-midwifery practice.  The conceptual framework for the research was based on theory proposed by Weidenbach (1967), which allowed the content and process of the prenatal visit to be examined as the components of prenatal care.  An exploratory descriptive design was followed.  Prenatal care was observed and data were collected by audio tape recordings of prenatal visits between the nurse-midwife and her client.  The collected data were transferred to a measurement instrument by the in investigator and submitted to computer analysis for descriptive statistics and correlation coefficients.  The sample was composed of 23 nurse-midwives, all members of the American College of Nurse-Midwives, from seven western states.  There were 40 clients and prenatal visits in the sample.  The gestational ages of the clients ranted from 12 to 41 weeks.  The study found that the average prenatal visits last 23.7 minutes, with the nurse-midwife talking for 12.6 minutes and the client talking for 4.9 minutes.  A significant other was present during 32.5% of the visits.  There was an average of four incidents of reassurance by the nurse-midwife per visit.  The content varied from visit to visit.  This may have been due to the client's gestational age and needs at a particular visit.  The clientâ€™s progress in her pregnancy and history since her previous visit were discussed in all visits for an average of 1.7 minutes.  There was evidence of continuity of care in 97.5% of the visits, family centered care in 72.5% of the visits, noninterventionist care in 52.5% of the visits, participative care in 47.5% of the visits, flexibility in care in 42.5% of the visits and consumer advocacy in 30% of the visits.  The clientâ€™s health status was discussed for an average of 0.7 minutes per visit.  Preparation for labor was discussed for an average of 0.5 minutes per visit.  Preventive health care, treatments, and preparation for parenthood were each discussed for 0.2 minutes per visit.  Significant relationships were found among several variables.  There were high correlations between the length of the visit and the amount of time taken by education and counseling (r=.74), and between the clientâ€™s age and the amount of verbalization by the client (r=.63).  There was also a significant relationship between the amount of time taken for the physical exam, and the amount of time taken for participative care (r=.57).  No significant relationship was found between the nurse-midwives' educational background and other measures.
Sonnenfleckenzeichnung Nr. 20889.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.10.1961, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Copper-regulated transcription of metallothionein genes in the yeast Candida glabrata
Creators: name: Thorvaldsen, Joanne Louise
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Copper is an essential metal ion for most organisms, yet the presence of excess copper ions is deleterious. Organisms have evolved systems to regulate the intracellular copper ion content tightly. The regulated synthesis of metal-binding metallothionein (MT) serves this purpose. This thesis presents a study on Cu-regulated MT synthesis in the yeast Candida glabrata. C. glabrata has three distinct MT genes (MTI, MTIIa and MTIIb) whose transcription is regulated by copper ions via the transcription factor AMT1. The first focus of this thesis is the in vivo analyses of the function and expression of the three MT genes. The second focus addresses the Cu-dependent function and structure of AMT1. To analyze the MTs in vivo it was necessary to develop tools to manipulate C. glabrata genetically. This included isolation of auxotrophic strains and identification of C. glabrata sequences which could confer autonomous replication in C. glabrata. The significance of MTII to copper tolerance was determined by disruption of MTIIa and MTIIb. The MT promoters were characterized using reporter constructs in C. glabrata. The Cu-dependent properties of AMT1 were studied using a heterologous expression system and purifying and analyzing the AMT1 DNA-binding domain. AMT1 was studied in Saccharomyces cerevisiae by measuring its ability to induce Cu-regulated expression from C. glabrata MT promoter sequences. The activity of AMT1 was also compared to ACE1, the analogous transcription factor in S. cerevisiae. A synthetic gene encoding the AMT1 DNA-binding domain was constructed enabling bacterial expression and purification of this domain. Various spectroscopic techniques were used to analyze how metal ions induce the AMT1 structure that interacts with DNA. In conclusion, my thesis describes cloning systems developed for C. glabrata, characterizes MT function and copper regulated MT promoter sequences in C. glabrata, demonstrates that AMT1 induces Cu-activated transcription of the three C. glabrata MT genes and that AMT1 is functionally homologous to ACE1 in S. cerevisiae, and presents evidence that a single Zn(II) and four clustered Cu(I) ions are responsible for inducing the AMT1 structure that interacts with DNA.
Architecture of hip hop
Creators: name: Gines, Jacob
Publisher: name: University of Utah
Year: 2012
Subjects: Inner city
Rap
Youth facilities

description: Being able to be true to yourself and speak  what is on your mind was and is the very foundation on which hip hop is structured. It has become a platform by which one's character and  identity is allowed to be made visible; not only to others but to the individual themselves.  In recent years main stream media has portrayed rap and hip hop music as thuggish,  misogynistic, and violent.... The airwaves are filled with songs which portray misogynistic images of women. This is what we are exposed to on a daily basis as to what hip hop is. Where has the message gone?  There is currently a movement to get back to the roots of hip hop. Activists in the industry such as Jay-Z, Russell Simmons, Kanye West, and others are at the forefront of this  t.  In response to thsi current state of hip hop and the ever present socioeconomic conditions of many of our inner cities I am proposing a Youth Center for Hip Hop Production and Performance.
Sonnenfleckenzeichnung Nr. 20908.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.10.1961, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.10.1961, erstellt von B. Jamnicky am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1961

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Blackburneus amazonicus Dellacasa 2011
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Aphodiidae
Blackburneus
Blackburneus amazonicus

description: Blackburneus amazonicus Dellacasa et al., 2011
Blackburneus amazonicus Dellacasa et al. 2011: 18 (Brazil (NA))
Distribution. Suriname: MHCN - NEW COUNTRY RECORD (Suriname, Sipaliwini, Puketi, (4°07′30″N, 54°37′30″W). 16/ 21-VII-2013. A. J. Hielkema. In pitfall with human excrements in forest.). French Guiana: Brûlé et al. 2014: 147. Brazil (NA): Dellacasa et al. 2011: 18 (NA).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 23, DOI: 10.5281/zenodo.3678492
Survey of cancer cases admitted to Salt Lake City hospitals 1925-1934 /
Creators: name: Parsons, Margaret Louise
Publisher: name: University of Utah
Year: 2012
Subjects: Statistics and Numerical Data

description: Findings can be given only for carcinoma and sarcoma.  So few cases are represented in the malignancies of hypernephroma, lymphosarcoms, malignant melanoma, Hodgkin's disease and chorionepithelioma, that no standards could be derived in this study.   Carcinoma forms 87.97% if all hospitalized cancer patients, and sarcoma drops second with  6.43%. Undoubtedly carcinoma forms the majority of malignant tumors.  However, the scarcity of other malignancies over a ten year period seem to need some explanation.  Altogether 2409 cases of cancer were studied.  Sixty-four of these were designated as "growth," "tumor," or "malignancy, and could be put under no classification.  It is interesting to notice that there were thirteen hospital deaths among these sixty-four cases.  Probably a large percentage of these patients were diagnosed as having a malignancy when a benign tumor was present,  or they had only the symptoms of a malignant growth.  No tabulations were made for these patients.  Information concerning them was too vague and scare to allow any certainty as their malignancy.  Of the 2409 patients 1262 were diagnosed pathologically as well as clinically.  That leaves about half of the patients diagnosed only by clinical methods.  Beside the fact the carcinoma is the commonest of malignant growth, mistaken diagnoses occur as to type of malignancy, and many of the tumors are recorded as carcinoma when in reality they were other types of malignancy.  These differences in classification were brought out in many of the pathological diagnoses.  For this thesis, however, the clinical diagnosis was accepted even though unaccompanied by a pathological report, and the resulting distribution of types of malignancy appeared.
The Microdistribution and retention of plutonium two thirty-nine on trabecular bone surfaces of the beagle : implications for the induction of osteosarcoma.
Creators: name: Wronski, Thomas Joseph
Publisher: name: University of Utah
Year: 2012
Subjects: Radiology
Isotopes
Radiactive Wastes

description: A study was initiated to investigate the relationship between the concentrations of 239Pu on trabecular bone surfaces and the rate of trabecular bone formation at specific skeletal sites of the beagle.  The contribution of the above parameters to the incidence of 239Pu-induced osteosarcomas was also evaluated.  Young adult beagles were administered single intravenous injections of ~0.016 um-Ci/kg of monomeric 239Pu-citrate.  Beagles injected with citrate only served as controls.  All animals were administered tetracycline derivatives intravenously in order to label activity forming bone surfaces.  Two 239Pu-injected beagles and a control were sacrificed at each of seven different time periods from 7 to 365 day post-injection.  Neutron-induced auto-radiographs were produced from thick bone sections subjected to a thermal neutron fluence of 10[16] n/cm2.  The 239Pu concentration on trabecular bone surfaces was determined from microscopic counts of fission fragment tracks.  The rate of trabecular bone formation was calculated from values for the surface/volume ratio of trabecular bone, the fractions of trabecular surface undergoing active bone formation, and the bone apposition rate.  The lumbar vertebra, pelvis, and proximal humerus, each of which exhibits a high incidence of 239Pu-induced osteosarcomas, were found to have a high initial concentration of 239Pu on their trabecular surfaces (~7-8 pCi/cm2) and a relatively high rate of trabecular bone formation.  The 239Pu concentration at these sites decreased to ~2-3 pCi/cm2 at the end of the first year.  On the other had, the skeletal sites with a low tumor incidence, the proximal ulna and distal humerus, had a low initial concentration of 239Pu on their trabecular surfaces (~1-2 pCI/cm2) and a significantly lower rate of trabecular bone formation.  The 239Pu concentration at these sites remained nearly constant throughout the experimental period.  These data suggest that the micro-distribution and retention of 239Pu on the surfaces of trabecular bone are intimately related to the rate of trabecular bone turnover.  Furthermore, it appears that a high initial deposition of 239Pu on trabecular surfaces and a high rate of trabecular bone turnover may contribute to the genesis of 239Pu-induced osteosarcomas.  This study revealed that there are significant intraskeletal variations in the rate of trabecular bone formation, the rate of trabecular bone apposition, the initial deposition of 239Pu on trabecular surfaces, and the incidence of 239Pu-induced osteosarcomas.  These variations appear to be related to the distribution of red and yellow marrow within the beagle skeleton, and may be the result of differences in the degree of vascularity of the two types of bone marrow.