cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Genetic analysis of LPHH1 in lung cancer
Creators: name: Louise. Lake, Sarah
Publisher: name: University of Liverpool Repository
Year: 2023

description: This thesis contends that the monarch-centred view of the masque, which has prevailed since the publication in the 1960s and 1970s of Stephen Orgel's seminal works on the genre, needs to be challenged in the light of recent scholarship on the cultural agency of other members of the royal family. In my introduction I argue that while the New Historicism has been crucial in elucidating the theatricalization of power in the early Stuart court, its insistence on the inevitability of the collusion between art and sovereign power needs to be questioned. The masque has long been seen as a monolithic and univocal celebration of monarchical power, despite the fact that it was promoted at court not by King James but by other members of the royal family. Adopting a loosely chronological approach, this thesis retells the story of the 'Jacobean' court masque by recovering the role played in the commissioning and performance of masques by James's wife, his children, and his male favourites. The chapters set out to hear voices other than that of the King, and discover that, while panegyric was part of each masque, it was rarely as unequivocal as traditional criticism has suggested. On the contrary, the annual masques were frequently appropriated to express the oppositional agendas of factions at court, and above all, of members of James's own family. I argue that Queen Anne set a precedent for the disruptive use of the masque which she exploited to present herself as independent from the King, and to emphasise her importance as the mother of the royal children. Prince Henry, and later Prince Charles, both used the masque to contest the pacifist policies of the King, while Buckingham's success as a favourite was linked to his skilful exploitation of the masques as an integral part of his self-fashioning. Above all by shifting the focus away from King James to consider the more active participation in the masque of other members of the royal family, this thesis offers a possibility of moving beyond the current impasse of the subversion / containment debate to a more nuanced reading of the culture of the early Stuart court which recognises the delicate process of negotiation and accommodation in which the masquers and their audiences were engaged.
Pharmaceutical Development and Analysis of Polyherbal Formulations as Ashmaghna Decoction (Kwatha) and Ashmaghna Tablet (Ghana Vati ) and Comparative Assessment of their Anti-Urolithiatic Activity in Wistar Albino Rats
Creators: name: Khanke, Shubham
name: Dr. Mujahid Khan
Publisher: name: Zenodo
Year: 2023
Subjects: Ashmaghna Kwatha, Ashmaghna Ghana Vati, organoleptic, anti-Urolithiatic, wistar rats

description: Pharmaceutical Development and Analysis of Polyherbal Formulations as Ashmaghna Decoction (Kwatha) and Ashmaghna Tablet (Ghana Vati ) and Comparative Assessment of their Anti-Urolithiatic Activity in Wistar Albino Rats
Can patient and pain characteristics predict manometric sphincter of Oddi dysfunction in patients with clinically suspected sphincter of Oddi dysfunction?
Creators: name: Elta, Grace H.
name: Orrell, Kyle
name: Cotton, Peter B.
name: Brawman-Mintzer, Olga
name: Romagnuolo, Joseph
name: Pauls, Qi
name: Freeman, Martin L.
name: Mauldin, Patrick
name: Serrano, Jose
name: Jamidar, Priya A.
name: Tarnasky, Paul R.
name: Drossman, Douglas A.
name: Fogel, Evan L.
name: Aliperti, Giuseppe
name: Kozarek, Richard A.
name: Durkalski, Valerie
name: Williams, April W.
name: Wilcox, C. Mel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Biliopancreatic-type postcholecystectomy pain, without significant abnormalities on imaging and laboratory test results, has been categorized as “suspected” sphincter of Oddi dysfunction (SOD) type III. Clinical predictors of “manometric” SOD are important to avoid unnecessary ERCP, but are unknown.
Intrinsic Time Quantum Geometrodynamics
Creators: name: Ita, Eyo Eyo
name: Soo, Chopin
name: Yu, Hoi-Lai
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Quantum Geometrodynamics with intrinsic time development and momentric variables is presented. An underlying SU(3) group structure at each spatial point regulates the theory. The intrinsic time behavior of the theory is analyzed, together with its ground state and primordial quantum fluctuations. Cotton-York potential dominates at early times when the universe was small; the ground state naturally resolves Penrose's Weyl Curvature Hypothesis, and thermodynamic and gravitational `arrows of time' point in the same direction. Ricci scalar potential corresponding to Einstein's General Relativity emerges as a zero-point energy contribution. A new set of fundamental commutation relations without Planck's constant emerges from the unification of Gravitation and Quantum Mechanics.
description: 6 pages
Recurrent intestinal metaplasia after radiofrequency ablation for Barrett’s esophagus: endoscopic findings and anatomic location
Creators: name: Cotton, Cary C.
name: Wolf, W. Asher
name: Shaheen, Nicholas J.
name: Ferrell, Kathleen
name: Spacek, Melissa B.
name: Dellon, Evan S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Radiofrequency ablation (RFA) is a safe and effective treatment for Barrett’s esophagus (BE) that results in high rates of complete eradication of intestinal metaplasia (CEIM). However, recurrence is common after CEIM and surveillance endoscopy is recommended. Neither the anatomic location nor the endoscopic appearance of these recurrences is well described.
title: Härtung eines KI Hardware Beschleunigers gegen strahleninduzierte Bitfehler
title: Hardening of an AI hardware accelerator against radiation-induced bit errors
Creators: name: Tas, Yunus
Publisher: name: Fachhochschule Dortmund
Year: 2023
Subjects: subject: 621.3 Elektrotechnik, Elektronik

description: In dieser Arbeit wird die Strahlenhärtung eines KI Hardware Beschleunigers beschreiben, in dem das Design mit dem Triple Modular Redundancy Generator Toolset (TMRG) vollständig tripliziert wird. Anschließend wird das triplizierte Design mit einer statischen und einer dynamischen Verifikation auf die korrekte Art der Triplizierung und seiner Funktionsweise untersucht. Zuletzt werden Simulationen mit drei verschiedenen Injektionstypen durchgeführt, in dem die tatsächliche Funktion der Voter durch Injektion von Single Event Upsets geprüft wird.
description: In this work, the radiation hardening of an AI hardware accelerator is described in which the design is fully triplicated using the Triple Modular Redundancy Generator Toolset (TMRG). Then, the triplicated design is examined with a static and a dynamic approach to verify the correct way of triplicating and its operation. Finally, simulations with three different injection types are performed, in which the actual function of the voter is tested by injecting single event upsets.
CBCL-PR: A Cognitively Inspired Model for Class-Incremental Learning in Robotics
Creators: name: Ayub, Ali
name: Wagner, Alan R.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Robotics (cs.RO)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: For most real-world applications, robots need to adapt and learn continually with limited data in their environments. In this paper, we consider the problem of Few-Shot class Incremental Learning (FSIL), in which an AI agent is required to learn incrementally from a few data samples without forgetting the data it has previously learned. To solve this problem, we present a novel framework inspired by theories of concept learning in the hippocampus and the neocortex. Our framework represents object classes in the form of sets of clusters and stores them in memory. The framework replays data generated by the clusters of the old classes, to avoid forgetting when learning new classes. Our approach is evaluated on two object classification datasets resulting in state-of-the-art (SOTA) performance for class-incremental learning and FSIL. We also evaluate our framework for FSIL on a robot demonstrating that the robot can continually learn to classify a large set of household objects with limited human assistance.
description: Accepted to IEEE Transactions on Cognitive and Developmental Systems
HALCOR: Data Integration and Interoperability in Manufacturing
Creators: name: Kostopoulou, Maria
Publisher: name: Zenodo
Year: 2023
Subjects: ontology
standard
data management
global workshop
ontology commons ecosystem
FAIR

description: Halcor’s use case focuses on the development of data ontologies that will serve as the foundation for a data-driven decision system for the procurement of raw materials (billets) for the Copper Tubes production plant. The goal is to unify data from different departments and entities involved in the procurement process, enabling knowledge preservation, standardization and ultimately, data integration and interoperability. The project’s main objective is to demonstrate the application of semantic technology in representing complex processes and capturing the expertise and knowledge of individual experts.
Self tuning scalar tensor black holes
Creators: name: Charmousis, Christos
name: Iosifidis, Damianos
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Studying a certain sub class of higher order Horndeski (scalar-tensor) theories we discuss a method discovered recently permitting analytic black hole solutions with a non trivial and regular scalar field. One of the solutions found has de Sitter asymptotics and self tunes the bulk cosmological constant. Using the aforementioned method we find and analyse new black hole solutions which can also have de Sitter asymptotics. By looking at small deviations of the integration constant responsible for self tuning we discuss the robustness of the self tuning mechanism. We find that neighboring solutions to the one previously found present also self tuning properties with unaltered effective cosmological constant.
description: References added
The explosion mechanism of core-collapse supernovae: progress in supernova theory and experiments
Creators: name: Foglizzo, Thierry
name: Kazeroni, Rémi
name: Guilet, Jérôme
name: Masset, Frédéric
name: González, Matthias
name: Krueger, Brendan K.
name: Novak, Jérôme
name: Oertel, Micaela
name: Margueron, Jérôme
name: Faure, Julien
name: Martin, Noël
name: Blottiau, Patrick
name: Peres, Bruno
name: Durand, Gilles
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The explosion of core-collapse supernova depends on a sequence of events taking place in less than a second in a region of a few hundred kilometers at the center of a supergiant star, after the stellar core approaches the Chandrasekhar mass and collapses into a proto-neutron star, and before a shock wave is launched across the stellar envelope. Theoretical efforts to understand stellar death focus on the mechanism which transforms the collapse into an explosion. Progress in understanding this mechanism is reviewed with particular attention to its asymmetric character. We highlight a series of successful studies connecting observations of supernova remnants and pulsars properties to the theory of core-collapse using numerical simulations. The encouraging results from first principles models in axisymmetric simulations is tempered by new puzzles in 3D. The diversity of explosion paths and the dependence on the pre-collapse stellar structure is stressed, as well as the need to gain a better understanding of hydrodynamical and MHD instabilities such as SASI and neutrino-driven convection. The shallow water analogy of shock dynamics is presented as a comparative system where buoyancy effects are absent. This dynamical system can be studied numerically and also experimentally with a water fountain. The potential of this complementary research tool for supernova theory is analyzed. We also review its potential for public outreach in science museums.
description: 19 pages, 6 figures, invited review accepted for publication in PASA
Sex and race and/or ethnicity differences in patients undergoing radiofrequency ablation for Barrett’s esophagus: results from the U.S. RFA Registry
Creators: name: Triadafilopoulos, George
name: Shaheen, Nicholas J.
name: Overholt, Bergein F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Little is known about differences in Barrett’s esophagus (BE) characteristics by sex, and race/ethnicity, or these differences in response to radiofrequency ablation (RFA).
Error control for the localized reduced basis multi-scale method with adaptive on-line enrichment
Creators: name: Ohlberger, Mario
name: Schindler, Felix
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: G.1.8
subject: 65G99, 65N55, 65N15, 35J20, 65N30, 76S05

description: In this contribution we consider localized, robust and efficient a-posteriori error estimation of the localized reduced basis multi-scale (LRBMS) method for parametric elliptic problems with possibly heterogeneous diffusion coefficient. The numerical treatment of such parametric multi-scale problems are characterized by a high computational complexity, arising from the multi-scale character of the underlying differential equation and the additional parameter dependence. The LRBMS method can be seen as a combination of numerical multi-scale methods and model reduction using reduced basis (RB) methods to efficiently reduce the computational complexity with respect to the multi-scale as well as the parametric aspect of the problem, simultaneously. In contrast to the classical residual based error estimators currently used in RB methods, we are considering error estimators that are based on conservative flux reconstruction and provide an efficient and rigorous bound on the full error with respect to the weak solution. In addition, the resulting error estimator is localized and can thus be used in the on-line phase to adaptively enrich the solution space locally where needed. The resulting certified LRBMS method with adaptive on-line enrichment thus guarantees the quality of the reduced solution during the on-line phase, given any (possibly insufficient) reduced basis that was generated during the offline phase. Numerical experiments are given to demonstrate the applicability of the resulting algorithm with online enrichment to single phase flow in heterogeneous media.
Correlations between charge radii differences of mirror nuclei and stellar observables
Creators: name: Bano, P.
name: Pattnaik, S. P.
name: Centelles, M.
name: Viñas, X.
name: Routray, T. R.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Nuclear Theory (nucl-th)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The correlation between the charge radii differences in mirror nuclei pairs and the neutron skin thickness has been studied with the so-called finite range simple effective interaction over a wide mass region. The so far precisely measured charge radii difference data within their experimental uncertainty ranges in the 34Ar-34S, 36Ca-36S, 38Ca-38Ar, and 54Ni-54Fe mirror pairs are used to ascertain an upper limit for the slope parameter of the nuclear symmetry energy L $\approx$ 100 MeV. This limiting value of L is found to be consistent with the upper bound of the NICER PSR J0740+6620 constraint at 1$σ$ level for the radius R$_{1.4}$ of 1.4 M$_\odot$ neutron stars. The lower bound of the NICER R$_{1.4}$ data constrains the lower limit of L to $\approx$ 70 MeV. Within the range for L = 70-100 MeV the tidal deformability $Λ^{1.4}$ constraint, which is extracted from the GW170817 event at 2$σ$ level, and the recent PREX-2 and CREX data on the neutron skin thickness are discussed.
description: 10 pages, 5 figures, 2 tables
Formation of the 3′ end of histone mRNA: Getting closer to the end
Creators: name: Marzluff, William F.
name: Dominski, Zbigniew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Nearly all eukaryotic mRNAs end with a poly (A) tail that is added to their 3’ end by the ubiquitous cleavage/polyadenylation machinery. The only known exception to this rule are metazoan replication dependent histone mRNAs, which end with a highly conserved stem-loop structure. This distinct 3’ end is generated by specialized 3’end processing machinery that cleaves histone pre-mRNAs 4–5 nucleotides downstream of the stem-loop and consists of the U7 small nuclear RNP (snRNP) and number of protein factors. Recently, the U7 snRNP has been shown to contain a unique Sm core that differs from that of the spliceosomal snRNPs, and an essential heat labile processing factor has been identified as symplekin. In addition, cross-linking studies have pinpointed CPSF-73 as the endonuclease, which catalyzes the cleavage reaction. Thus, many of the critical components of the 3’ end processing machinery are now identified. Strikingly, this machinery is not as unique as initially thought but contains a number of factors involved in cleavage/polyadenylation, suggesting that the two mechanisms have a common evolutionary origin. The greatest challenge that lies ahead is to determine how all these factors interact with each other to form a catalytically competent processing complex capable of cleaving histone pre-mRNAs.
title: Leveraging Modelling and Machine Learning for the Analysis of Curvilinear Structures in Medical Images
titleType: Other
Creators: name: Annunziata, Roberto
Publisher: name: University of Dundee
Year: 2016

description: Recent clinical research has highlighted important links between a number of diseases and the tortuosity of curvilinear anatomical structures such as corneal nerve fibres, suggesting that tortuosity changes might detect early stages of specific conditions. Currently, clinical studies are mainly based on subjective, visual assessment, with limited repeatability and inter-observer agreement.

In this thesis I have endeavoured to address these problems by proposing a fully automated framework for image-level tortuosity estimation, consisting of a hybrid segmentation method and a versatile tortuosity estimation algorithm. The former combines an appearance model, based on a Scale and Curvature Invariant Ridge Detector (SCIRD), with a context model, including multi-range learned context filters. The latter is based on a novel tortuosity estimation paradigm in which discriminative, multi-scale features can be automatically learned for specific anatomical objects and diseases.

I have validated each module of the system separately and then assessed their impact on the tortuosity estimation performance (target application). The segmentation module has been tested on 5 challenging data sets, including corneal nerve fibres (not public, provided by our clinical collaborators at MEEI, Harvard Medical School, USA), neurites (2 benchmark data sets) and retinal blood vessels (2 benchmark data sets). The tortuosity estimation module has been validated on a data set including 140 corneal nerve images, the largest ever used for this task, to my best knowledge.

Experimental results show that (1) the segmentation module outperforms state-of-the-art hand-crafted and hybrid approaches; (2) the tortuosity estimation module performs better than state-of-the-art and widely used tortuosity indices; (3) the whole system matches and sometimes even exceeds tortuosity estimation performance of experienced observers when compared against each other, a level of performance that will allow us to deploy the system on much larger data sets, with the aim of discovering new links between tortuosity and specific diseases in an objective and repeatable fashion.
A note on stability shifting for the Muskat problem
Creators: name: Córdoba, Diego
name: Gómez-Serrano, Javier
name: Zlatoš, Andrej
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In this note, we show that there exist solutions of the Muskat problem that shift stability regimes: they start unstable, then become stable, and finally return to the unstable regime. We also exhibit numerical evidence of solutions with medium-sized $L^{\infty}$ norm of the derivative of the initial condition that develop a turning singularity.
description: 12 pages, 4 figures
Corrigendum to “A Congestion Alleviation Technique Exploiting Structural Insights on the Interaction of Line Loading Limits, Reactance and Line Outage Security Constraints”
Creators: name: Cuffe, Paul
name: Beiranvand, Arash
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 400805
subject: Electrical energy transmission, networks and systems

description: The authors regret that the published manuscript contains a typographic error in labelling a reactance value for a particular line in both Fig. 1 and Fig. 2 of the original manuscript. In both of these cases, the reactance of the line A → C should be labelled as 0.1 pu. The other lines in these diagrams should be annotated with reactances of 1 pu but the central line A → C should be 0.1 pu. These figures are provided here without these misleading typographic errors.

Original manuscript:

A. Beiranvand and P. Cuffe, "A Congestion Alleviation Technique Exploiting Structural Insights on the Interaction of Line Loading Limits, Reactance and Line Outage Security Constraints," in IEEE Transactions on Power Systems, vol. 38, no. 4, pp. 3719-3732, July 2023, doi: 10.1109/TPWRS.2022.3198487.
Mechanical regulation of signaling pathways in bone
Creators: name: Rubin, Clinton T.
name: Thompson, William R.
name: Rubin, Janet
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: A wide range of cell types depend on mechanically induced signals to enable appropriate physiological responses. The skeleton is particularly dependent on mechanical information to guide the resident cell population towards adaptation, maintenance and repair. Research at the organ, tissue, cell and molecular levels has improved our understanding of how the skeleton can recognize the functional environment, and how these challenges are translated into cellular information that can site-specifically alter phenotype. This review first considers those cells within the skeleton that are responsive to mechanical signals, including osteoblasts, osteoclasts, osteocytes and osteoprogenitors. This is discussed in light of a range of experimental approaches that can vary parameters such as strain, fluid shear stress, and pressure. The identity of mechanoreceptor candidates is approached, with consideration of integrins, pericellular tethers, focal adhesions, ion channels, cadherins, connexins, and the plasma membrane including caveolar and non-caveolar lipid rafts and their influence on integral signaling protein interactions. Several mechanically regulated intracellular signaling cascades are detailed including activation of kinases (Akt, MAPK, FAK), β-catenin, GTPases, and calcium signaling events. While the interaction of bone cells with their mechanical environment is complex, an understanding of mechanical regulation of bone signaling is crucial to understanding bone physiology, the etiology of diseases such as osteoporosis, and to the development of interventions to improve bone strength.
Primordial Star Formation under the Influence of Far Ultraviolet Radiation: 1540 Cosmological Halos and the Stellar Mass Distribution
Creators: name: Hirano, Shingo
name: Hosokawa, Takashi
name: Yoshida, Naoki
name: Omukai, Kazuyuki
name: Yorke, Harold W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We perform a large set of cosmological simulations of early structure formation and follow the formation and evolution of 1540 star-forming gas clouds to derive the mass distribution of primordial stars. The star formation in our cosmological simulations is characterized by two distinct populations, the so-called Population III.1 stars and primordial stars formed under the influence of far ultraviolet (FUV) radiation (Population III.2D stars). In this work, we determine the stellar masses by using the dependences on the physical properties of star-forming cloud and/or the external photodissociating intensity from nearby primordial stars, which are derived from the results of two-dimensional radiation hydrodynamic simulations of protostellar feedback. The characteristic mass of the Pop III stars is found to be a few hundred solar masses at z ~ 25, and it gradually shifts to lower masses with decreasing redshift. At high redshifts z > 20, about half of the star-forming gas clouds are exposed to intense FUV radiation and thus give birth to massive Pop III.2D stars. However, the local FUV radiation by nearby Pop III stars becomes weaker at lower redshifts, when typical Pop III stars have smaller masses and the mean physical separation between the stars becomes large owing to cosmic expansion. Therefore, at z < 20, a large fraction of the primordial gas clouds host Pop III.1 stars. At z =< 15, the Pop III.1 stars are formed in relatively cool gas clouds due to efficient radiative cooling by H_2 and HD molecules; such stars have masses of a few x 10 Msun. Since the stellar evolution and the final fate are determined by the stellar mass, Pop III stars formed at different epochs play different roles in the early universe.
description: 22 pages, 19 figures, published in MNRAS
Scene Separation & Data Selection: Temporal Segmentation Algorithm for Real-Time Video Stream Analysis
Creators: name: Xin, Yuelin
name: Zhou, Zihan
name: Xia, Yuxuan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences
subject: I.4.8

description: We present 2SDS (Scene Separation and Data Selection algorithm), a temporal segmentation algorithm used in real-time video stream interpretation. It complements CNN-based models to make use of temporal information in videos. 2SDS can detect the change between scenes in a video stream by com-paring the image difference between two frames. It separates a video into segments (scenes), and by combining itself with a CNN model, 2SDS can select the optimal result for each scene. In this paper, we will be discussing some basic methods and concepts behind 2SDS, as well as presenting some preliminary experiment results regarding 2SDS. During these experiments, 2SDS has achieved an overall accuracy of over 90%.
description: 5 pages, 4 figures, at IJCAI-ECAI 2022 workshop, First International Workshop on Spatio-Temporal Reasoning and Learning, July 24, 2022, Vienna, Austria
Distribution of Histone3 Lysine 4 Trimethylation at T3-Responsive Loci in the Heart During Reversible Changes in Gene Expression
Creators: name: KOBAYASHI, MIKA
name: WADA, YOUICHIRO
name: KODAMA, TATSUHIKO
name: MIMURA, IMARI
name: KOHRO, TAKAHIDE
name: PANDYA, KUMAR
name: SMITHIES, OLIVER
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Expression in the adult heart of a number of cardiac genes, including the two genes comprising the cardiac Myosin heavy chain locus (Myh), is controlled by thyroid hormone (T3) levels, but there is minimal information concerning the epigenetic status of the genes when their expressions change. We fed mice normal chow or a Propyl thio uracil (PTU, an inhibitor of T3 production)-diet for 6 weeks, or the PTU diet for 6 weeks followed by normal chow for a further two weeks. Heart ventricles from these groups were then used for ChIP-seq analyses with an antibody to H3K4me3, a well documented epigenetic marker of gene activation. The resulting data show that, at the Myh7 locus, H3K4me3 modifications are induced primarily at 5’ transcribed region in parallel with increased expression of beta myosin heavy chain (MHC). At the Myh6 locus, decreases in H3K4me3 modifications occurred at the promoter and 5’ transcribed region. Extensive H3K4me3 modifications also occurred at the intergenic region between the two Myh genes which extended into the 3’ transcribed region of Myh7. The PTU-induced changes in H3K4me3 levels are, for the most part, reversible but are not invariably complete. We found full restoration of Myh6 gene expression upon PTU withdrawal, however the H3K4me3 pattern was only partially restored at Myh6, suggesting that full re-expression of Myh6 does not require that the H3K4me3 modifications return fully to the untreated conditions. Together, our data show that the H3K4me3 modification is an epigenetic marker closely associated with changes in Myh gene expression.
A two-phase model for studying the complex interplay between natural convection and magnetic field in aluminum-oxide/water nanofluid
Creators: name: Liao, Chuan-Chieh
name: Lin, Kuang C.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: While previous experimental studies revealed the existence of optimal heat transfer performance in natural convection of magnetohydrodynamic (MHD) nanofluid flows, it is believed that this phenomenon is not unique in different levels of magnetic flux density. In order to prove this speculation, we numerically investigate the influence of the magnetic field on steady natural convection of aluminum-oxide (Al2O3) nanofluids inside an enclosure. The MHD flow model without the consideration of nanofluids is well validated against theoretical, numerical, and experimental results. The nanofluid in the present investigation has temperature-dependent physical properties and is modeled by a two-phase mixture considering thermophoresis and Brownian diffusion. While varying the volume fraction of nanoparticles from 0 to 6%, we methodically examine the effect of the Hartmann number on the heat transfer performance through the thermal behavior map in terms of the Hartmann–Rayleigh plane. Depending on the combination of magnetic intensity and buoyancy-induced flow, the nanofluid heat transfer with the addition of various concentrations of nanoparticles can be categorized into two patterns separated by a critical Hartmann number: the presence of a maximum Nusselt number (Type A) and continuously increased heat transfer rates (Type B) over a wide range of the Rayleigh number from 103 to 106 and the Hartmann number from 0 to 300. Described by a piecewise-defined function, the critical Hartmann number is exponentially proportional to the Rayleigh number from 104 to 106 and rises linearly in a logarithmic scale with elevating the Rayleigh number from 103 to 104.
Harnessing lightweight design potentials via the Materials Data Space
Creators: name: Huschka, Martin
Publisher: name: Zenodo
Year: 2023
Subjects: ontology
standard
data management
global workshop
ontology commons ecosystem
FAIR

description: Additive manufacturing (AM) offers enormous lightweight potential due to great design freedom. Heterogeneous and decentralised data in the value chain must be integrated to obtain accurate knowledge of the material, the product and the manufacturing process. This use case shows that sharing data over institutions can unlock further lightweight potentials if semantic interoperability and data sovereignty are preserved.
title: Kicking at the Closet Door: The Opinions, Attitudes, and Experiences of Military Homosexuals
Creators: name: Parks, Rodney Lee
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 2000

description: The purpose of this study is to investigate the opinions, attitudes, and experiences of active-duty homosexual/bisexual military servicemembers. Very little research currently exists on this topic because the sample population remains hidden among the ranks of their heterosexual counterparts for fear of discrimination, harassment, and physical violence. Using a snowball sampling technique, survey analysis was conducted to analyze the relationship among homosexual/bisexual military servicemembers and assess their experiences. Most homosexual men and women serve effectively in the military and are proud of their military performance. Although many homosexuals join the military to suppress their desires, the majority (70%) felt that military service actually helped them accept their homosexuality/bisexuality. The "Don't Ask, Don't Tell" policy has also had a positive affect helping to integrate homosexuals into military service, though many felt their performance evaluations were adversely affected by their sexuality.
Xtn3 is a developmentally expressed cardiac and skeletal muscle-specific novex-3 titin isoform
Creators: name: Davis, Anna C.
name: Brown, Daniel D.
name: Conlon, Frank L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Titin proteins play an essential role in maintaining muscle function and structure. Recent work has implicated the involvement of the novex-3 titin isoform in sarcomere restructuring and disease. Unlike avian and mammalian systems, Xenopus laevis myogenesis is characterized by a wave of primary myogenesis followed by apoptosis of the primary muscles and formation of new muscles by secondary myogenesis. We show here that the Xenopus laevis novex-3 titin isoform (Xtn3) is developmentally expressed throughout the somites, heart, and primary muscles of the developing embryo. Downregulation of Xtn3 expression at tadpole stages appears to coincide with the change in myofiber composition from solely embryonic “fast” fiber types to myofibers containing both “fast” and “slow” fiber types. We demonstrate that Xtn3 is expressed early in the presomitic mesoderm and remains expressed in the somites, ventral myoblasts, and developing jaw muscles through late tailbud stage. Furthermore, we show that Xtn3 is expressed in the cardiac primordia prior to linear heart tube formation and remains expressed in the heart until tadpole stage, at which point it is downregulated in the heart except in discrete patches of cardiac cells. Finally, we demonstrate that Xtn3 transcripts are detectable in adult heart and muscle tissues.
A longitudinal study of the effects of differing primary science experience on the level of interest and achievement of girls and boys in their first year of secondary science
Creators: name: Craig, Jan
Publisher: name: Loughborough University
Year: 2019
Subjects: subject: 169999 Studies in Human Society not elsewhere classified
subject: FOS: Sociology

description: This research study addresses four key questions. Are pupils who have studied substantial amounts of primary science more interested in science than those who have not? Is there any longer-term effect on their interest in science? Is there any link between pupils' interest in primary science and their achievement in secondary science? Are there particular features of primary science which appear to be associated with higher levels of interest in science? A sample of about 300 pupils, aged 10–11 years, was selected comprised of 15 fourth year primary classes which fed into two comprehensive schools. The primary school topics studied, the apparatus used and the pupils' interest in scientific activities, both in and out of school, was assessed by means of questionnaires. Further illuminative information concerning science schemes, classroom organisation and teaching style was collected by means of observation and structured interviews with teachers. [Continues.]
Numerical tests of the envelope theory for few-boson systems
Creators: name: Semay, Claude
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The envelope theory, also known as the auxiliary field method, is a simple technique to compute approximate solutions of Hamiltonians for $N$ identical particles in $D$-dimension. The accuracy of this method is tested by computing the ground state of $N$ identical bosons for various systems. A method is proposed to improve the quality of the approximations by modifying the characteristic global quantum number of the method.
description: A reference is updated. To appear in Few-Body Systems
Wakey-Wakey: Animate Text by Mimicking Characters in a GIF
Creators: name: Xie, Liwenhan
name: Zhou, Zhaoyu
name: Yu, Kerun
name: Wang, Yun
name: Qu, Huamin
name: Chen, Siming
Publisher: name: arXiv
Year: 2023
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Graphics (cs.GR)
subject: FOS: Computer and information sciences

description: With appealing visual effects, kinetic typography (animated text) has prevailed in movies, advertisements, and social media. However, it remains challenging and time-consuming to craft its animation scheme. We propose an automatic framework to transfer the animation scheme of a rigid body on a given meme GIF to text in vector format. First, the trajectories of key points on the GIF anchor are extracted and mapped to the text's control points based on local affine transformation. Then the temporal positions of the control points are optimized to maintain the text topology. We also develop an authoring tool that allows intuitive human control in the generation process. A questionnaire study provides evidence that the output results are aesthetically pleasing and well preserve the animation patterns in the original GIF, where participants were impressed by a similar emotional semantics of the original GIF. In addition, we evaluate the utility and effectiveness of our approach through a workshop with general users and designers.
description: Accepted in the 36th Annual ACM Symposium on User Interface Software and Technology (UIST'23)
Information-Entropic for Travelling Solitons in Lorentz and CPT Breaking Systems
Creators: name: Correa, R. A. C.
name: da Rocha, Roldao
name: Dutra, A. de Souza
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this work we group three research topics apparently disconnected, namely solitons, Lorentz symmetry breaking and entropy. Following a recent work [Phys. Lett. B 713 (2012) 304], we show that it is possible to construct in the context of travelling wave solutions a configurational entropy measure in functional space, from the field configurations. Thus, we investigate the existence and properties of travelling solitons in Lorentz and CPT breaking scenarios for a class of models with two interacting scalar fields. Here, we obtain a complete set of exact solutions for the model studied which display both double and single-kink configurations. In fact, such models are very important in applications that include Bloch branes, Skyrmions, Yang-Mills, Q-balls, oscillons and various superstring-motivated theories. We find that the so-called Configurational Entropy (CE) for travelling solitons, which we name as travelling Configurational Entropy (TCE), shows that the best value of parameter responsible to break the Lorentz symmetry is one where the energy density is distributed equally around the origin. In this way, the information-theoretical measure of travelling solitons in Lorentz symmetry violation scenarios opens a new window to probe situations where the parameters responsible for breaking the symmetries are random. In this case, the TCE selects the best value.
Aperture Coupled Microstrip Antenna Design and Analysis using MATLAB
Creators: name: Damaraju, Sri Sai Satyanarayana
Publisher: name: figshare
Year: 2019
Subjects: subject: 100501 Antennas and Propagation
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: A linearly-polarized aperture coupled patch antenna design is characterized by using MATLAB software. The aperture coupled patch antenna microstrip feedline, substrates, ground plane slot, and patch dimensions are varied to determine effects on antenna performance which eliminates the electrical connection between the radiating conductors and feed by employing dielectric substrates separated by a ground plane. If exact combination of slot and shape of feed is chosen, it gives an optimum impedance bandwidth with an improved radiation pattern.
The powerful jet of an off-nuclear intermediate-mass black hole in the spiral galaxy NGC 2276
Creators: name: Mezcua, M.
name: Roberts, T. P.
name: Lobanov, A. P.
name: Sutton, A. D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Jet ejection by accreting black holes is a mass invariant mechanism unifying stellar and supermassive black holes (SMBHs) that should also apply for intermediate-mass black holes (IMBHs), which are thought to be the seeds from which SMBHs form. We present the detection of an off-nuclear IMBH of $\sim$5 $\times$ 10$^{4}$ M$_\odot$ located in an unusual spiral arm of the galaxy NGC 2276 based on quasi-simultaneous \textit{Chandra} X-ray observations and European VLBI Network (EVN) radio observations. The IMBH, NGC2276-3c, possesses a 1.8 pc radio jet that is oriented in the same direction as large-scale ($\sim$650 pc) radio lobes and whose emission is consistent with flat to optically thin synchrotron emission between 1.6 GHz and 5 GHz. Its jet kinetic power ($4 \times 10^{40}$ erg s$^{-1}$) is comparable to its radiative output and its jet efficiency ($\geq$ 46\%) is as large as that of SMBHs. A region of $\sim$300 pc along the jet devoid of young stars could provide observational evidence of jet feedback from an IMBH. The discovery confirms that the accretion physics is mass invariant and that seed IMBHs in the early Universe possibly had powerful jets that were an important source of feedback.
description: 7 pages, 2 figures, accepted for publication in MNRAS
Evaluation logs for Open Source Ventilator projects based on OSH readiness Scale
Creators: name: Trinadh Geddam
Publisher: name: Zenodo
Year: 2023

description: This is a random sample of references to open source ventilators based on the data published by the PubInv project (https://github.com/PubInv/covid19-vent-list CC0-1.0). It was used to verify technology and documentation readiness scales introduced in a CIRP design conference paper. This upload shall make the data set used for the conference paper publicly accessible.
Induced geometry from disformal transformation
Creators: name: Yuan, Fang-Fang
name: Huang, Peng
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this note, we use the disformal transformation to induce a geometry from the manifold which is originally Riemannian. The new geometry obtained here can be considered as a generalization of Weyl integrable geometry. Based on these results, we further propose a geometry which is naturally a generalization of Weyl geometry.
description: 15 pages, references added
Molecular and functional analysis of Drosophila single-minded larval central brain expression
Creators: name: Crews, Stephen T.
name: Pearson, Joseph C.
name: Lau, Daniel C.
name: Talsky, Kristin Benjamin
name: Freer, Stephanie M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Developmental regulatory proteins are commonly utilized in multiple cell types throughout development. The Drosophila single-minded (sim) gene acts as master regulator of embryonic CNS midline cell development and transcription. However, it is also expressed in the brain during larval development. In this paper, we demonstrate that sim is expressed in 3 clusters of anterior central brain neurons: DAMv1/2, BAmas1/2, and TRdm and in 3 clusters of posterior central brain neurons: a subset of DPM neurons, and two previously unidentified clusters, which we term PLSC and PSC. In addition, sim is expressed in the lamina and medulla of the optic lobes. MARCM studies confirm that sim is expressed at high levels in neurons but is low or absent in neuroblasts (NBs) and ganglion mother cell (GMC) precursors. In the anterior brain, sim+ neurons are detected in 1st and 2nd instar larvae but rapidly increase in number during the 3rd instar stage. To understand the regulation of sim brain transcription, 12 fragments encompassing 5’-flanking, intronic, and 3’-flanking regions were tested for the presence of enhancers that drive brain expression of a reporter gene. Three of these fragments drove expression in sim+ brain cells, including all sim+ neuronal clusters in the central brain and optic lobes. One fragment upstream of sim is autoregulatory and is expressed in all sim+ brain cells. One intronic fragment drives expression in only the PSC and laminar neurons. Another downstream intronic fragment drives expression in all sim+ brain neurons, except the PSC and lamina. Thus, together these two enhancers drive expression in all sim+ brain neurons. Sequence analysis of existing sim mutant alleles identified 3 likely null alleles to utilize in MARCM experiments to examine sim brain function. Mutant clones of DAMv1/2 neurons revealed a consistent axonal fasciculation defect. Thus, unlike the embryonic roles of sim that control CNS midline neuron and glial formation and differentiation, postembryonic sim, instead, controls aspects of axon guidance in the brain. This resembles the roles of vertebrate Sim that have an early role in neuronal migration and a later role in axonogenesis.
Evaluation logs for Open Source Ventilator projects based on OSH readiness Scale
Creators: name: Trinadh Geddam
Publisher: name: Zenodo
Year: 2023

description: The open source readiness levels of Open Source ventilator projects from the list in https://docs.google.com/spreadsheets/d/1inYw5H4RiL0AC_J9vPWzJxXCdlkMLPBRdPgEVKF8DZw/edit#gid=0 Projects with openess level of 3 were chosen, however those with no access as on the date of evaluation have been rejected.