cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
sj-pdf-3-wso-10.1177_17474930211046758 - Supplemental material for Patterns of ischemic posterior circulation strokes: A clinical, anatomical, and radiological review
Creators: name: Salerno, Alexander
name: Strambo, Davide
name: Nannoni, Stefania
name: Dunet, Vincent
name: Michel, Patrik
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-3-wso-10.1177_17474930211046758 for Patterns of ischemic posterior circulation strokes: A clinical, anatomical, and radiological review by Alexander Salerno, Davide Strambo, Stefania Nannoni, Vincent Dunet and Patrik Michel in International Journal of Stroke
sj-docx-1-npx-10.1177_1934578X211033735 - Supplemental material for Natural Indoles From the Bacterium Pseudovibrio denitrificans P81 Isolated From a Marine Sponge, Aaptos Species
Creators: name: Fang, Shu-Yen
name: Chen, Sheng-Yuan
name: Chen, You-Ying
name: Kuo, Tsu-Jen
name: Wen, Zhi-Hong
name: Chen, Yu-Hsin
name: Hwang, Tsong-Long
name: Sung, Ping-Jyun
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-npx-10.1177_1934578X211033735 for Natural Indoles From the Bacterium Pseudovibrio denitrificans P81 Isolated From a Marine Sponge, Aaptos Species by Shu-Yen Fang, Sheng-Yuan Chen, You-Ying Chen, Tsu-Jen Kuo, Zhi-Hong Wen, Yu-Hsin Chen, Tsong-Long Hwang and Ping-Jyun Sung in Natural Product Communications
sj-docx-1-tae-10.1177_20420188211044943 – Supplemental material for The prognostic value of thyroid-stimulating immunoglobulin in the management of Graves’ disease
Creators: name: Zhou, Yulin
name: Zhou, Mengxi
name: Qi, Yicheng
name: Wang, Weiqing
name: Chen, Xinxin
name: Wang, Shu
Publisher: name: SAGE Journals
Year: 2021
Subjects: Endocrinology
Paediatrics
Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-1-tae-10.1177_20420188211044943 for The prognostic value of thyroid-stimulating immunoglobulin in the management of Graves’ disease by Yulin Zhou, Mengxi Zhou, Yicheng Qi, Weiqing Wang, Xinxin Chen and Shu Wang in Therapeutic Advances in Endocrinology and Metabolism
NURSE RESILIENCE AND ITS APPLICATION IN UNDERSTANDING NURSES’ JOB STRESS: A STRUCTURAL EQUATION MODELING APPROACH
Creators: name: Cai, Yun
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Nursing not elsewhere classified

description: This study follows a resource-recovery-adaptation approach, where nurses’ personal and external resources, a potential recovery mechanism, and a positive outcome are operationalized from an existing dataset obtained from a multi-state sample of registered nurses in the United States. Data was collected in two Press Ganey surveys, the Employee Survey and the Resilience Survey, in 2018. The surveys were administered in over one thousand healthcare organizations, including acute care hospitals, medical practice groups, outpatient surgery centers, children's hospitals, home health organizations as well as other ancillary services (Press Ganey Associates, 2018). The surveys contained items measuring nurses’ perceptions of their organizations (i.e., community commitment, diversity and inclusion, employee care, compensation, and service and quality), their direct work environments (i.e., leadership, teamwork, staffing level, and job resources), and their work (i.e., job stress, job satisfaction, commitment to the nursing profession, and work-life balance), as well as nurses’ demographic characteristics (i.e., age, sex, race, tenure, shift, and full-time/part-time status).
RISK OF BONE METASTATIZATION IN BREAST CANCER:ROLE OF MATRIX METALLOPROTEINASES AND ADAMS TISSUE EXPRESSION
Creators: name: LUCIANI, ANDREA
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: INTRODUCTION Breast cancer is the most common female neoplasm in developed countries: it represents the first cause of death for cancer in women between 40-55 years old. Bone metastasis are common in patients affected by advanced breast cancer. In patients affected by metastatic breast cancer (MBC), the bone represents the most common site of metastatization. Some elements can explain the high frequency of bone metastasis: the blood flow is abundant in the bone marrow, the cancer cells produce adhesion molecules than link stromal cells and bone matrix, the bone tissue is a source of growth factors. Bone metastasis from breast cancer are usually ostheolytic. The matrix metalloproteinases (MMPs) are able to degrade all ECM components; ADAMs functions include cellular adhesion, migration and signaling. Their principal substrates are transmembrane proteins as adhesion proteins and precursors of growth factors and cytokines. OBJECTIVES OF THE STUDY This mono institutional study evaluates the expression of a panel of biological and molecular markers (MMP, ADAMs and TIMPS) in two cohorts of patients with breast cancers affected or not affected by bone metastasis. The main end point is to verify if there is some marker significantly correlated with the risk of bone metastatization. PATIENTS AND METHODS 297 records of breast cancer patients operated between 1985 and 2001 at San Paolo Hospital in Milan were analyzed. All avaible slides were revised, stained with hematossilin and eosin, Tissue Microarray (TMA) was created with Tissue Arrayer Minicore instrument. RESULTS Mean age of the population is 61 years (standard deviation 11.7; range 27-89 years). The control group has 207 patients (69,7% of the total). The group with bone metastasis consists of 90 patients (31,3% of the total). Of those, 45 (50%) have only bone localization of disease while 50% have both visceral and bone metastasis. In the control group, 173 patients out of 206 (83,6%) had ductal invasive carcinoma, 25 patients (12,1%) had lobular invasive carcinoma while 9 patients (4,3%) had other hystotype. Tumoral grading, MMP1, ADAM 17 and ADAM 12 were the parameters selected by the univariate analysis. ADAM12 expression was the only parameter significantly different between the two groups (78,26% vs 91,11% with p 0.036, OR=2.59, 95%IC 1.06-6.29). DICUSSION Our study shows that ADAM 12 is the only hyper expressed protein in tumoral tissue that is significant related with bone matastatization. ADAM12 induces estrogen-resistance in hormone sensitive tumors, play a role as mediator of the resistance to the hormonal treatment. 73,3% had a ER-positive and ADAM12-positive disease. It can be hypothesized that some ormonosensitive patients, treated with hormones would develop bone metastatization due to hyperexpression of ADAM12. Targeting ADAM12, together with hormonal treatment, could be a new approach to overcome anti estrogenic resistance.
Additional file 1 of Evaluation of the efficacy of manual soft tissue therapy and therapeutic exercises in patients with pain and limited mobility TMJ: a randomized control trial (RCT)
Creators: name: Gębska, Magdalena
name: Dalewski, Bartosz
name: Pałka, Łukasz
name: Kołodziej, Łukasz
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: Cancer
subject: Science Policy

description: Additional file 1: Supplement 1.
มวลชีวภาพและการสะสมแคโรทีนอยด์ในสาหร่ายสีเขียวขนาดเล็กสายพันธุ์ PY202 ภายใต้สภาวะมิกโซโทรฟิก
Creators: name: ณิมนาราห์ อยู่คงแก้ว
name: ปรียานุช เจริญสุข
name: ปีลดา เชิดชูเกียรติศักดิ์
name: ธัญนันท์ วรรณธง บรอคเคิลเฮอร์สท์
Publisher: name: กองบริหารการวิจัย มหาวิทยาลัยธรรมศาสตร์
Year: 2560
Subjects: สาหร่ายสีเขียวขนาดเล็ก, กลูโคส, คีโตแคโรทีนอยด์, แคนธาแซนธิน

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 25, 4
Analysis of Infinite-Server Queueing Models In A Random Environment
Creators: name: Liu, Yiran
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Stochastic analysis and modelling
Probability theory
Operations research

description: In this thesis we study infinite server queues driven by Cox processes in a random environment. More specifically, we consider a Cox/Gt/∞ infinite server queueing model with the arrival rate modeled as a highly fluctuating stochastic process, which arguably takes into account some small time scale variations often observed in practice. We prove a homogenization property for this system, which yields an approximation by an Mt/Gt/∞ queue with some effective parameters. That is, in the fast oscillatory context, we show how the Cox/Gt/∞ queueing system in a random environment can be approximated by a more classical Markovian system. We also establish diffusion approximations to the (re-scaled) number-in-system process by proving functional central limit theorems (FCLTs) using a stochastic homogenization framework. This framework permits the establishment of quenched and annealed limits in a unified manner. At the quantitative level, the so-called subcritical and supercritical regimes indicate the relative dominance between the two underlying stochasticities driving the system: the randomness in the arrival intensity and that in the service times. The results illustrate intricate interactions between the underlying driving forces of the system.
การเจริญเติบโตของต้นเจตมูลเพลิงแดง (Plumbago indica L.) หลังออกปลูกเมื่อขยายพันธุ์ด้วยการเพาะเลี้ยงเนื้อเยื่อและปริมาณสาร plumbagin
Creators: name: เยาวพา จิระเกียรติกุล
name: ปพิชญา ขวานทอง
name: ภาณุมาศ ฤทธิไชย
name: ศรีโสภา เรืองหนู
name: อรุณพร อิฐรัตน์
Publisher: name: กองบริหารการวิจัย มหาวิทยาลัยธรรมศาสตร์
Year: 2560
Subjects: เจตมูลเพลิงแดง, plumbagin, การเจริญเติบโต, การเพาะเลี้ยงเนื้อเยื่อพืช, ราก

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 25, 4
STUDIO DEI DISTURBI GASTROINTESTINALI NEI BAMBINI AFFETTI DA DISTURBI DELLO SPETTRO AUTISTICO
Creators: name: OLIVARI, BENEDETTA
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: L?autismo � un disturbo cognitivo e comportamentale che generalmente si manifesta nei primi tre anni di vita ed � caratterizzato da una compromissione grave e generalizzata in diverse aree dello sviluppo: compromissione della socializzazione, della comunicazione verbale e non verbale, dell?attivit� immaginativa e presenza di modalit� di comportamento ristrette e ripetitive.
Rappresenta un capitolo molto complesso e dibattuto, soprattutto sul piano eziopatogenetico.
Viene riconosciuta all?autismo una genesi multifattoriale con una rilevante componente
genetica ed ambientale, tuttavia la sua patogenesi non � ancora sufficientemente conosciuta.
Sebbene non siano presenti tra i criteri diagnostici, vi sono nella recente letteratura molte segnalazioni relative alla presenza di sintomi gastrointestinali nei bambini autistici (DGI) con una prevalenza che pu� variare, secondo le diverse statistiche, da una frequenza pressoch� normale rispetto alla popolazione generale fino alla quasi totalit� dei pazienti.
Il presente studio si � posto tre obiettivi principali: giungere all?individuazione e alla classificazione sistematica della presenza dei DGI dei bambini che vengono diagnosticati nel nostro ambulatorio e di quelli gi� seguiti dal punto di vista riabilitativo-terapeutico; valutare l?esistenza di una correlazione tra i dati clinici (presenza di sintomatologia gastroenterologica) e grado di alterazione ai test di laboratorio (Calprest, Test di Permeabilit� Intestinale Lattulosio/Mannitolo); individuare, sulla base dei dati emersi, possibili modelli di trattamento specifici e precoci.
Verranno presentati i risultati relativi alla definizione di uno specifico protocollo diagnostico, all?incidenza e tipologia dei DGI nel nostro campione, all?esecuzione dei test laboratoristici e ai trattamenti intrapresi.
Additional file 1 of Single cell lineage tracing reveals clonal dynamics of anti-EGFR therapy resistance in triple negative breast cancer
Creators: name: Pellecchia, Simona
name: Franchini, Melania
name: Viscido, Gaetano
name: Arnese, Riccardo
name: Gambardella, Gennaro
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Supplementary Material 1.
sj-docx-1-qjp-10.1177_17470218211048060 – Supplemental material for Data-driven group comparisons of eye fixations to dynamic stimuli
Creators: name: Onwuegbusi, Tochukwu
name: Hermens, Frouke
name: Hogue, Todd
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-qjp-10.1177_17470218211048060 for Data-driven group comparisons of eye fixations to dynamic stimuli by Tochukwu Onwuegbusi, Frouke Hermens and Todd Hogue in Quarterly Journal of Experimental Psychology
MAPPING GLOBAL RESEARCH TRENDS IN DEEP VENOUS THROMBOSIS NURSING: A CITESPACE ANALYSIS
Creators: name: Dr. Elena, Rossi
name: Prof. Marco, Bianchi
Publisher: name: continental journal
Year: 2024
Subjects: Venous thromboembolism, deep vein thrombosis, pulmonary thromboembolism, nursing prevention, literature analysis

description: Venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT) and pulmonary thromboembolism (PT), poses a significant risk to hospitalized patients, often resulting in unexpected fatalities. Each year, more than 10 million individuals worldwide fall victim to DVT, making it a global health concern. Early intervention has proven effective in mitigating the incidence, disability, and mortality associated with DVT. Recognizing the urgency of the issue, many nations prioritize VTE prevention as a pivotal component of healthcare quality management, underscoring the growing importance of nursing staff in this context. This study employs software-driven visual analysis to scrutinize literature on DVT prevention from both domestic and international sources, accessible through the China National Knowledge Infrastructure (CNKI) and Web of Science (SCI). The goal is to unveil research hotspots and emerging trends in the field of DVT nursing, providing valuable insights for future scholars and enhancing clinical DVT prevention and nursing quality.
Essere e Verit� nella mediazione del Logos in Joseph Mar�chal
Creators: name: BAGGIO, TOMMASO
Publisher: name: Universit� degli Studi del Piemonte Orientale Amedeo Avogadro
Year: 2017

description: L?ultima configurazione della dottrina di Joseph Mar�chal si contraddistingue per la rigorosa delineazione di un orizzonte speculativo capace di far emergere le condizioni di possibilit� per una convergenza tra la riflessione trascendentale di Kant e la metafisica dell?essere di Tommaso
d?Aquino. L?esigenza di determinare l?oggettivit� della conoscenza, e di evitare alcune aporie gnoseologiche, spinge alla rimodulazione del dinamismo intellettivo in virt� dell?analisi critica e della teoria realista. Il fattore portante della ricerca viene trovato nel logos come nesso necessario di pensiero e realt�; l?articolazione della riscoperta della dimensione logico-ontologica implica il riconoscimento della circolarit� virtuosa di ?a priori? e ?a posteriori? e fornisce un punto di partenza per la metafisica. La rinnovata analisi delle cause formali, efficienti e finali si attua in sinergia con la ripresa della valenza forte (e anti-relativistica) di concetti come ?sostanza? e ?trascendentale?. I cardini della ricognizione risiedono nella analogia d?essere - analogia di proporzionalit� e, soprattutto, di attribuzione-proporzione - e negli elementi direttamente connessi; assumono particolare rilievo il principio di identit� e non-contraddizione e la distinzione tra essenza e atto d?essere. Tale quadro epistemico rende ragione del condizionato e dell?esperienza, superando cos� la problematicit� del rapporto fenomeno-noumeno, in forza della scoperta teoretica dell?incondizionato in quanto fondamento assoluto e trascendente. In questo snodo vengono tematizzate sia la creazione e la partecipazione, le quali connotano il rapporto tra il finito e l?Infinito, sia la differenza ontologica radicale tra l?ente, in quanto esistenza contingente, e l?Essere sussistente. Questo percorso verso l?Essere necessario si intreccia inoltre con le questioni della persona e della libert� e, come ricerca di Dio, profila un?apertura ai temi della rivelazione e della Trinit�.
sj-pdf-2-cjk-10.1177_20543581211046077 – Supplemental material for A Randomized Controlled Trial of Comparative Efficacy between Sodium Bicarbonate and Heparin as A Locking Solution for Tunneled Central Venous Catheters Among Patients Requiring Maintenance Hemodialysis
Creators: name: Wathanavasin, Wannasit
name: Phannajit, Jeerath
name: Poosoonthornsri, Manorom
name: Lewsuwan, Songkiat
name: Tanateerapong, Patchara
name: Chongthanakorn, Kamonrat
name: Takkavatakarn, Kullaya
name: Katavetin, Pisut
name: Tiranathanagul, Khajohn
name: Eiam-ong, Somchai
name: Susantitaphong, Paweena
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental material, sj-pdf-2-cjk-10.1177_20543581211046077 for A Randomized Controlled Trial of Comparative Efficacy between Sodium Bicarbonate and Heparin as A Locking Solution for Tunneled Central Venous Catheters Among Patients Requiring Maintenance Hemodialysis by Wannasit Wathanavasin, Jeerath Phannajit, Manorom Poosoonthornsri, Songkiat Lewsuwan, Patchara Tanateerapong, Kamonrat Chongthanakorn, Kullaya Takkavatakarn, Pisut Katavetin, Khajohn Tiranathanagul, Somchai Eiam-ong and Paweena Susantitaphong in Canadian Journal of Kidney Health and Disease
Additional file 1 of A murine model for the del(GJB6-D13S1830) deletion recapitulating the phenotype of human DFNB1 hearing impairment: generation and functional and histopathological study
Creators: name: Domínguez-Ruiz, María
name: Murillo-Cuesta, Silvia
name: Contreras, Julio
name: Cantero, Marta
name: Garrido, Gema
name: Martín-Bernardo, Belén
name: Gómez-Rosas, Elena
name: Fernández, Almudena
name: del Castillo, Francisco J.
name: Montoliu, Lluís
name: Varela-Nieto, Isabel
name: del Castillo, Ignacio
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 1.
sj-pdf-1-lal-10.1177_09639470211047817 – Supplemental Material for Reading and analysing short story collections. An empirical study of readers’ interpretation process of Benni’s Il bar sotto il mare
Creators: name: De Vooght, Edward
name: Nemegeer, Guylian
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature

description: Supplemental Material, sj-pdf-1-lal-10.1177_09639470211047817 for Reading and analysing short story collections. An empirical study of readers’ interpretation process of Benni’s Il bar sotto il mare by Edward De Vooght and Guylian Nemegeer in Language and Literature
Clinical and instrumental evaluation of Botulinum Toxin type A safety profile in post stroke spasticity rehabilitation treatment
Creators: name: BARICICH, Alessio
Publisher: name: Universit� degli Studi del Piemonte Orientale Amedeo Avogadro
Year: 2018

description: Post stroke spasticity (PSS) occurs approximately in 30% of stroke survivors. Spasticity varies from a subtle neurological sign to a gross increase in tone causing immobility of joints. PSS is associated with several complications, increasing care needs and utilisation of healthcare resources. Botulinum toxin type A (BoNT-A) has been considered as an effective and safe treatment for focal spasticity in stroke survivors, with low prevalence of complications, reversibility of effect, and efficacy in reducing spastic hypertonia. Recent studies estimated that a significant percentage of patients affected by PSS could benefit from higher doses than those permitted by current country directives. However, at present time, there is no general consensus on the maximum dose of BoNT-A in terms of safety and clinical interchangeability among the three commercially approved products (abobotulinumtoxinA, onabotulinumtoxinA, incobotulinumtoxinA).
In light of these considerations, the aim of this thesis is to investigate the safety profile of BoNT-A high doses in the treatment of post stroke spasticity.
In our research activity we investigated the clinical effect of this treatment in severely affected patients, focusing on both clinical and instrumental assessment of systemic effects of BoNT-A.
sj-pdf-1-pul-10.1177_20458940211041500 - Supplemental material for Plasma ADAMTS13 and von Willebrand factor in diagnosis and prediction of prognosis in pulmonary arterial hypertension
Creators: name: Ahmed, Abdulla
name: Ahmed, Salaheldin
name: Rådegran, Göran
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-pul-10.1177_20458940211041500 for Plasma ADAMTS13 and von Willebrand factor in diagnosis and prediction of prognosis in pulmonary arterial hypertension by Abdulla Ahmed, Salaheldin Ahmed and Göran Rådegran in Pulmonary Circulation
Le glosse antico alto tedesche alla Regula Pastoralis (Codex St. Galli 218)
Creators: name: CIRIMELE, FERNANDA
Publisher: name: Universit� degli studi di Bergamo
Year: 2006

description: Questo lavoro analizza le glosse antico alto tedesche alla Regula Pastoralis di Gregorio Magno contenute nel Codex St. Galli 218. Il corpus glossatorio consiste in nove glosse interlineari: quattro verbi (ammonet-leret, suscitet-mundere, existit-hist, grassantur-grimment), tre sostantivi (livor-smerza, percussione-harinscara, propitiationem-pisuneda) e due avverbi (minime-nuith, gratis- undurftis). La differenza di grafia, a volte minuta come nel caso della glossa smerza, o vistosa e insolita come nella glossa harinscara, sottolinea il fatto che queste glosse sono state apposte da mani diverse, pertanto non � possibile attribuire un'esatta datazione all'intero corpus. Tuttavia alcune di loro, come leret, mundere e undurftis mostrano cambiamenti linguistici ricorrenti in Notker, per cui si potrebbe ipotizzare che esse risalgano probabilmente al X sec. Il rapporto tra lemmi ed interpretamenta mostra congruenza sia nella forma grammaticale che nella semantica. Le strutture grammaticali dei lemmi latini e quelle degli interpretamenta in volgare vengono perfettamente rispettate. Le glosse sono tutte in massima parte frequenti, tranne smerza e undurftis, che occorrono, come glosse, esclusivamente in questo corpus.
Identification of new variants in patients with neurodegenerative disorders by whole genome sequencing data and development of a bioinformatic pipeline
Creators: name: CROCE, ROBERTA
Publisher: name: Universit� degli Studi del Piemonte Orientale Amedeo Avogadro
Year: 2021

description: We explored the missing heritability in a cohort of 140 patients affected by Neurodegenerative disorders (NDDs), including Amyotrophic Lateral Sclerosis (ALS), Frontotemporal dementia (FTD)) Parkinson disease (PD) and Spinocerebellar Ataxia (SCA). We performed Whole Genome Sequencing (WGS) after excluding pathogenic variants in the main disease-relevant causative genes and investigated 3 classes of potentially pathogenic variants: a)Coding/non-coding SNV/Indels in a panel of 696 genes involved in NODs. Using standard annotation, we identified pathogenic/likely pathogenic variants (ACMG) in genes causative of tare forms of each disease (N=15) and in gene causing a NND different from patient clinical presentation (N=15). In addition to the standard annotation we used SpliceAl, a deep leaming tool predicting an effect on splicing mechanism. We found 48 rare variants with a possible splicing Impact (ASTM 0.4). We performed in vitro studies for 9 variants (highest AS) and for 6 of them, we confirmed their role in splicing
alteration. b)Genome-wide structural variants Using CNVkit, we identified a 15925 deletion (1.2Mb) in a PD case. Similar deletions has been associated with mild intellectual disability and dysmorphisms but never reported in PD. c)Genome wide Tandem Repeat (TR). Using literature (ExpansionHunter, GangSTR) and novel tools, we Identified 4 novel loci in ALS cohort with a possible TR expansion and replicated the results in larger independent cohorts from Italy (763 ALS, 1018 controls) and International Mine project (3121 ALS, 1217 controls). For 3 of them (FRA1DAC1, RFC1, HK1) the result was not replicated. For the last locus (TFG2) the preliminary data are promising since the TR was observed only in patient and in none controls (1/352 vs 0/292 in ITFG2). In conclusion, using a multilevel WGS data analysis we were able to find missed pathogenetic variants In genes associated with different NDDs, reinforcing the idea of a shared genetic cause among these diseases.
sj-pdf-5-pul-10.1177_20458940211041500 - Supplemental material for Plasma ADAMTS13 and von Willebrand factor in diagnosis and prediction of prognosis in pulmonary arterial hypertension
Creators: name: Ahmed, Abdulla
name: Ahmed, Salaheldin
name: Rådegran, Göran
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-5-pul-10.1177_20458940211041500 for Plasma ADAMTS13 and von Willebrand factor in diagnosis and prediction of prognosis in pulmonary arterial hypertension by Abdulla Ahmed, Salaheldin Ahmed and Göran Rådegran in Pulmonary Circulation
sj-pdf-3-ome-10.1177_00302228211049879 - Supplemental material for Turkish Muslim Physicians' and Nurses' Views About the Do Not Resuscitate Order: A Cross-Sectional Two Center Study
Creators: name: Çuvalci, Burcu
name: Akbal, Yağmur
name: Hintistan, Sevilay
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-3-ome-10.1177_00302228211049879 for Turkish Muslim Physicians' and Nurses' Views About the Do Not Resuscitate Order: A Cross-Sectional Two Center Study by Burcu Çuvalci, Yağmur Akbal and Sevilay Hintistan in OMEGA-Journal of Death and Dying
Delay discounting in at-risk preadolescents: Brain mechanisms and behavior
Creators: name: Butcher, Tarah J
Publisher: name: Purdue University Graduate School
Year: 2022
Subjects: Neurosciences not elsewhere classified

description: It is well documented that adolescent substance use is associated with deficits in brain function and behavior. However, possible deficits that predate substance use initiation remain poorly characterized in preadolescents at-risk for developing substance use disorder (SUD). To characterize potential brain and behavioral differences that predate substance use, substance naïve preadolescents, ages 11–12, were recruited into three groups to complete functional magnetic resonance imaging delay discounting: (1) High-risk youth (n=35) with a family history of SUD and externalizing psychiatric disorders, (2) psychiatric controls (n=35) with no family history of SUD, but equivalent externalizing psychiatric disorders as high-risk youth, and (3) healthy controls (n=29) with no family history of SUD and minimal psychopathology. While no behavioral differences between groups were identified, there were group differences in posterior cingulate cortex (PCC) function during decision making. Specifically, the high-risk group showed stronger deactivation of the PCC than healthy controls. These results suggest that high-risk preadolescents may need to suppress activity of key nodes of the default mode network (a task negative network) to a greater extent to properly allocate attention to the task.
A Philosophical Analysis of the Play Concept
Creators: name: Rose, Jason Liban
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Philosophy not elsewhere classified

description: This philosophical dissertation concerns the nature of play, a nebulous concept that is nonetheless vitally important to understanding the human being. Play is older than the spoken word and represents a mode of being in the world for many animals, including us. Many thinkers have attempted to unravel the mysteries of play but it has long resisted attempts to fully capture it. I begin Part One by defining play – a trickier proposition that one might expect – and examining the biological origin of the instinct for play in boredom and fun. Part One is a genetic account of play. Part Two contains a memetic account of play – these five chapters look at personal, human play in particular. They cover five philosophical topics: how the play concept has been used in the history of philosophy, the phenomenological experience of play, the relations between play and reason, the aesthetic and ethical dimensions of play, and the relation between play and the production of culture. By examining the discourse surrounding the concept of play in these spheres of human activity, this treatise provides a thorough philosophical understanding of play as a foundation upon which future studies of the play concept can build.
Questions of Style: Legal Drafting Manuals and Scientific Style Manuals in Contemporary English
Creators: name: WILLIAMS, CHRISTOPHER
name: SEOANE, ELENA
Publisher: name: Universit� degli studi di Bergamo
Year: 2006

description: In questo articolo prendiamo in esame i manuali di stile in lingua inglese di due aree dei linguaggi settoriali contemporanei, vale a dire l?inglese giuridico (LE = ?Legal English?) e l?inglese scientifico (SE = ?Scientific English?). Il nostro scopo � innanzitutto quello di individuare le caratteristiche salienti dei manuali nei rispettivi campi, per poi analizzare alcune delle principali somiglianze e differenze nei pareri e nei suggerimenti forniti nei manuali a coloro che devono redigere testi giuridici oppure elaborare testi scientifici. Il nostro obiettivo � di individuare con maggiore precisione quali strategie retoriche sono alla base della produzione dei testi nei rispettivi settori, e condizionano quindi il modo in cui tali testi vengono elaborati. Per rendere possibile tale confronto � stato necessario compilare due piccoli corpora aventi circa le stesse dimensioni, uno per i manuali giuridici, l?altro per i manuali scientifici.
Déposer ses données sur Recherche Data Gouv
Creators: name: Arènes, Cécile
name: Akdogan, Meriç
Publisher: name: Zenodo
Year: 2024
Subjects: entrepôt de données
data repository
données de recherche
research data
science ouverte
open science

description: Slides : présentation de Recherche Data Gouv (30minutes)

La partie Démonstration de la formation a été réalisée directement sur le site (1h)
Déposer ses données sur Recherche Data Gouv
Creators: name: Arènes, Cécile
name: Akdogan, Meriç
name: Moisan, Aurélien
Publisher: name: Zenodo
Year: 2024
Subjects: entrepôt de données
data repository
données de recherche
research data
science ouverte
open science
Recherche Data Gouv

description: Slides : présentation de Recherche Data Gouv (45minutes)

La partie Démonstration de la formation a été réalisée directement sur le site (1h)
การศึกษาเปรียบเทียบผลของปุ๋ยอินทรีย์และปุ๋ยเคมีต่อความสามารถในการผลิตจิงจูฉ่าย
Creators: name: อรประภา เทพศิลปวิสุทธิ์
Publisher: name: กองบริหารการวิจัย มหาวิทยาลัยธรรมศาสตร์
Year: 2560
Subjects: จิงจูฉ่าย, ดิน, ปุ๋ยมูลไก่, ผลตอบแทนทางเศรษฐกิจ, ผลผลิต

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 25, 4
ผลของมูลโคและน้ำหมักชีวภาพต่อการเจริญเติบโตและผลผลิตของบรอคโคลี
Creators: name: คริษฐ์สพล หนูพรหม
name: อมรรัตน์ ชุมทอง
name: พงษ์ศักดิ์ มานสุริวงศ์
name: ฝนทิพย์ ทองนุ้ย
Publisher: name: กองบริหารการวิจัย มหาวิทยาลัยธรรมศาสตร์
Year: 2560
Subjects: บรอคโคลี, ปุ๋ยเคมี, มูลโค, น้ำหมักชีวภาพ

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 25, 4
The IDDIR: an informal insurance arrangement in Ethiopia
Creators: name: AREDO, DEJENE
Publisher: name: Universit� degli studi di Bergamo
Year: 2010

description: In the absence of formal insurance services, smallholder farmers are devoid of effective ways of managing numerous risks they encounter in their daily lives. One response mechanisms common among rural households is reliance on network-based collective action arrangement driven by motives of reciprocity and altruism. The indigenous financial institutions constitute a striking example of risk-sharing and risk-pooling arrangements widely practiced by the bulk of rural communities in Africa. Of these arrangements, the Ethiopian iddir can be considered as a unique and viable institution worth investigation to understand its nature and logic. Drawing on the synthesis of the available literature and household surveys, this study attempts to explain the essence and dynamism of iddir; describe its risk-pooling and risk-sharing mechanisms; investigate the principles and rules underlying its procedures and operations. It also assesses its rules using an analytical framework known as the ?institutional analysis and development framework?. This study can contribute to the debate concerning the logic and potential of informal institutions in, partially, meeting the insurance needs of smallholder farmers. It is important to understand and promote the mechanisms by which indigenous arrangements attempt to bridge
the gap left by the formal sector.
Déposer ses données sur Recherche Data Gouv
Creators: name: Arènes, Cécile
Publisher: name: Zenodo
Year: 2023
Subjects: entrepôt de données
data repository
données de recherche
research data
science ouverte
open science

description: Slides : présentation de Recherche Data Gouv (30minutes) La partie Démonstration de la formation a été réalisée directement sur le site (1h)
MPEC 2024-O35 : 2023 HB7
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
sj-pdf-1-imr-10.1177_03000605211043241 - Supplemental material for Relationship of the platelet distribution width/platelet count ratio with thyroid antibody levels in patients with Hashimoto's thyroiditis
Creators: name: Demir, Aslıhan Dilara
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-imr-10.1177_03000605211043241 for Relationship of the platelet distribution width/platelet count ratio with thyroid antibody levels in patients with Hashimoto's thyroiditis by Aslıhan Dilara Demir in Journal of International Medical Research
Additional file 5 of Genetic insights into superior grain number traits: a QTL analysis of wheat-Agropyron cristatum derivative pubing3228
Creators: name: Wang, Jiansheng
name: Wang, Erwei
name: Cheng, Shiping
name: Ma, Aichu
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 5
Genetic Architecture of Complex Psychiatric Disorders -- Discoveries and Methods
Creators: name: Yang, Zhiyu
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Genetics not elsewhere classified

description: Impacting individual’s social and physical well-being, psychiatric disorders have been a substantial burden on public health. As such disorders are frequently observed aggregating in families, we can expect a large involvement of heritable components underlying their etiologies. Therefore, studying the genetic architecture and basis is one of the most important aims toward developing effective treatments for psychiatric disorders. The overall objective of this dissertation is to contribute to understanding the genetics of psychiatric disorders. Analyzing summary statistics from genomewide association studies (GWAS) of psychiatric disorders, we mainly present results of two projects. In the first one, we evaluated commonalities and distinctions in genetic risk of four highly comorbid childhood onset neuropsychiatric disorders: attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), obsessive-compulsive disorder (OCD) and Tourette’s syndrome (TS). Through systematic analysis of genetic architecture and correlation, we confirmed exitance of genetic components shared across ADHD, ASD and TS, as well as OCD and TS. Subsequently, we identified those components at variant, gene, and tissue specificity levels through meta-analyses. Our results pointed toward possible involvement of hypothalamus-pituitary-adrenal (HPA) axis, a human stress response system, in the etiology of these childhood onset disorders. The second project includes the proposition of a novel framework for general GWAS summary statistics-based analyses. Instead of regular odds ratio and standard errors archived in the summary statistics, we proposed a recounstruction approach to rewrite the results in terms of single nucleotide polymorphisms (SNP) allelic and genotypic frequencies. We also put forward three applications built-upon the proposed framework, and evaluated the performance on both synthetic data and real GWAS results of psychiatric disorders for each of them. Through these three applications, we demonstrated that this framework can broaden the scope of GWAS summary statistics-based analyses and unify various of analyses pipelines. We hope our work can serve as a stepping-stone for future researchers aiming at understanding and utilizing GWAS results of complex psychiatric disorders.
Verso nuovi rimedi amministrativi? Modelli giustiziali a confronto.
Creators: name: Falcon, Giandomenico
name: Marchetti, Barbara
Publisher: name: Universit� degli studi di Trento
Year: 2015

description: Questo volume � dedicato ai rimedi alternativi alla giurisdizione nell?ambito delle liti tra privato e pubblica amministrazione ed offre a questa prospettiva il contributo della comparazione. Esso volge dunque lo sguardo alle esperienze di alcuni Paesi europei, riflette su potenziali vantaggi e inconvenienti legati all?introduzione di ?nuovi? rimedi amministrativi e va alla ricerca dei difetti dei diversi sistemi rimediali alternativi e dei possibili correttivi.
A questo scopo, gli studi in esso contenuti esaminano non solo le tecniche di alternative dispute resolution in senso stretto, ma pi� in generale ogni via stragiudiziale di risoluzione della lite, sia che essa passi attraverso la costruzione di un?amministrazione giustiziale, sia che si concretizzi in strumenti di mediazione, conciliazione o transazione del rapporto controverso.
� cos� esaminato anzitutto il sistema dei ricorsi amministrativi in alcune esperienze nazionali (Germania, Francia e Regno Unito, Italia) e sovranazionali (Unione europea), e sono poi considerati oltre alle procedure di ricorso dinanzi alle autorit� indipendenti, gli istituti della mediazione e della transazione, indagati anche in prospettiva comparata.
L?attenzione � rivolta, in particolare, a verificare se le promesse ? in termini di flessibilit�, specializzazione, celerit�, economicit�, imparzialit� ? dei rimedi alternativi siano mantenute o quali ostacoli eventualmente si frappongano a che ci� avvenga. L?indagine tuttavia non � semplice, dacch� le esperienze e gli istituti analizzati sono eterogenei e difficili da comparare, si calano in contesti anche culturalmente assai diversi, e presentano punti di forza e di debolezza non corrispondenti.
Il volume incrocia anche, inevitabilmente, l?annosa questione della problematica conciliabilit� dei tradizionali meccanismi di alternative dispute resolution con il potere autoritativo dell?amministrazione: qui, proprio il confronto con le altre esperienze europee sembra confermare come la non completa disponibilit� delle posizioni controverse induca a impiegare con cautela istituti, quali la mediazione e la conciliazione, che hanno il loro terreno privilegiato di elezione nei rapporti privati.
Ne risulta, in sintesi, un quadro complesso e articolato, che tuttavia gli studi raccolti in questo volume possono contribuire, ci sembra, a rendere pi� chiaro.
sj-pdf-2-imr-10.1177_03000605211047779 - Supplemental material for A rare case of type II negative pressure pulmonary edema following extraction of inhaled peanuts in a 21-month-old boy
Creators: name: Li, Qin
name: Zhou, Liang
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Health and Community Services
subject: Cardiology
subject: Dentistry not elsewhere classified
subject: Emergency Medicine
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Nursing not elsewhere classified
subject: Nutrition and Dietetics not elsewhere classified
subject: Oncology and Carcinogenesis not elsewhere classified
subject: Orthopaedics
subject: Sports Medicine
subject: Otorhinolaryngology
subject: Aged Health Care
subject: Paediatrics
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Public Health and Health Services not elsewhere classified
subject: Respiratory Diseases
subject: Sociological Methodology and Research Methods
subject: Surgery

description: Supplemental material, sj-pdf-2-imr-10.1177_03000605211047779 for A rare case of type II negative pressure pulmonary edema following extraction of inhaled peanuts in a 21-month-old boy by Qin Li and Liang Zhou in Journal of International Medical Research
Ars longa, vita brevis; or: On the relationship between historical linguistics and typology
Creators: name: CUZZOLIN, Pierluigi
Publisher: name: Universit� degli Studi di Bergamo
Year: 2006

description: In latino, soprattutto arcaico, esistono frasi di carattere per lo pi� gnomico del tipo ?ars longa, vita brevis?. Combinando i dati della tipologia e della linguistica comparata all?interno della famiglia indeuropea (vedico e lituano), si trovano indizi sufficienti per supporre che questo antico tipo sintattico, residuale in latino, fosse un?antica strategia per esprimere il comparativo in indeuropeo.
Caroline Balling Master'sThesis: Clinician Perception of the Clinical Utility of the Hierarchical Taxonomy of Psychopathology (HiTOP) System
Creators: name: Balling, Caroline Elizabeth
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Clinical psychology

description: The standard of diagnosing and categorizing mental disorders in the United States has long been the Diagnostic and Statistical Manual of Mental Disorders (DSM), but the DSM has been criticized through evidence suggesting it lacks appropriate validity, reliability, and clinical utility. The Hierarchical Taxonomy of Psychopathology (HiTOP) has been offered as a solution to these criticisms. But the recommendation to replace the DSM and its categorical diagnostic system has been met with doubt and criticism by others in the field. A common sentiment in these critiques is a lack of evidence that the HiTOP dimensions are clinically useful or that clinicians would be open to applying them to their patients. The goal of the present study was to compare clinician perceptions of the HiTOP and DSM systems for the conceptualization of clinical cases. A sample of actively practicing clinicians (n = 143) rated one of three clinical vignettes using the HiTOP and DSM systems then rated the two approaches on seven indices of clinical utility. HiTOP was favored for overall clinical utility score as well as utility for formulating effective intervention, communicating clinical information to the client, comprehensively describing client psychopathology, describing global functioning, and ease of applying the system to the individual. There was no preference between HiTOP and the DSM for communicating with other mental health providers. The DSM was not favored for any clinical utility outcome. These results suggest interest in HiTOP and dissatisfaction with the DSM among clinicians.
A Complete Fiasco: The Difficulties Of Dealing With Atomic Data And A (Possible) Pythonic Solution
Creators: name: Barnes, Will
Publisher: name: Zenodo
Year: 2018
Subjects: python
pyastro18
astronomy
CHIANTI
atomic-data
solar-physics
atomic-physics

description: Atomic data is used ubiquitously throughout the astrophysics and astronomy community. Whether it is performing radiative transfer calculations in a protoplanetary disk or interpreting observed spectra in the solar corona, observers and modelers alike rely heavily on vast amounts of detailed atomic data. These databases, which contain data from both laboratory experiments and large simulation codes, are often difficult to access, have no common format, and require a great deal of effort (and funding) to assemble. One such example is the [CHIANTI atomic database][1] which has been maintained continuously since 1995 and is heavily used by solar physicists. Recently I've begun work on a package called [fiasco][2] (the Italian name for the style of bottle used to store a Chianti wine) which provides a high-level interface to the CHIANTI database. In this talk, I'll discuss the difficulties of working with this data, the software and techniques used to parse the data, and the high-level interface. Additionally, and most importantly, I will discuss the possible use of fiasco as a general interface to any atomic database and how this might extend the usefulness of the package into the general astronomy community. My hope is that this last point in particular will generate much discussion and interest in how to improve programmatic interfaces to this type of data.

[1]: http://www.chiantidatabase.org/

[2]: https://github.com/wtbarnes/fiasco
description: See the GitHub repository here: https://github.com/wtbarnes/pyastro-2018-talk
Additional file 1 of CircXRN2 suppresses tumor progression driven by histone lactylation through activating the Hippo pathway in human bladder cancer
Creators: name: Xie, Bo
name: Lin, Juntao
name: Chen, Xianwu
name: Zhou, Xuejian
name: Zhang, Yan
name: Fan, Mengjing
name: Xiang, Jiayong
name: He, Ning
name: Hu, Zhenghui
name: Wang, Feifan
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Supplementary File 1. The information of BCa patients.