cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Risk factors associated with severe hospital burden of COVID-19 disease in Regione Lombardia: a cohort study
Creators: name: Presanis, Anne M.
name: Kunzmann, Kevin
name: Grosso, Francesca M.
name: Jackson, Christopher H.
name: Corbella, Alice
name: Grasselli, Giacomo
name: Salmoiraghi, Marco
name: Gramegna, Maria
name: De Angelis, Daniela
name: Cereda, Danilo
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Research
COVID-19
Hospital-fatality risk
Critical care
Multi-state model
Mixture model

description: Abstract: Background: Understanding the risk factors associated with hospital burden of COVID-19 is crucial for healthcare planning for any future waves of infection. Methods: An observational cohort study is performed, using data on all PCR-confirmed cases of COVID-19 in Regione Lombardia, Italy, during the first wave of infection from February-June 2020. A multi-state modelling approach is used to simultaneously estimate risks of progression through hospital to final outcomes of either death or discharge, by pathway (via critical care or not) and the times to final events (lengths of stay). Logistic and time-to-event regressions are used to quantify the association of patient and population characteristics with the risks of hospital outcomes and lengths of stay respectively. Results: Risks of severe outcomes such as ICU admission and mortality have decreased with month of admission (for example, the odds ratio of ICU admission in June vs March is 0.247 [0.120–0.508]) and increased with age (odds ratio of ICU admission in 45–65 vs 65 + age group is 0.286 [0.201–0.406]). Care home residents aged 65 + are associated with increased risk of hospital mortality and decreased risk of ICU admission. Being a healthcare worker appears to have a protective association with mortality risk (odds ratio of ICU mortality is 0.254 [0.143–0.453] relative to non-healthcare workers) and length of stay. Lengths of stay decrease with month of admission for survivors, but do not appear to vary with month for non-survivors. Conclusions: Improvements in clinical knowledge, treatment, patient and hospital management and public health surveillance, together with the waning of the first wave after the first lockdown, are hypothesised to have contributed to the reduced risks and lengths of stay over time.
Matter trispectrum: theoretical modelling and comparison to N-body simulations
Creators: name: Gualdi, Davide
name: Novell-Masot, Sergi
name: Gil-Marín, Héctor
name: Verde, Licia
Publisher: name: arXiv
Year: 2020
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The power spectrum has long been the workhorse summary statistics for large-scale structure cosmological analyses. However, gravitational non-linear evolution moves precious cosmological information from the two-point statistics (such as the power spectrum) to higher-order correlations. Moreover, information about the primordial non-Gaussian signal lies also in higher-order correlations. Without tapping into these, that information remains hidden. While the three-point function (or the bispectrum), even if not extensively, has been studied and applied to data, there has been only limited discussion about the four point/trispectrum. This is because the high-dimensionality of the statistics (in real space a skew-quadrilateral has 6 degrees of freedom), and the high number of skew-quadrilaterals, make the trispectrum numerically and algorithmically very challenging. Here we address this challenge by introducing the i-trispectrum, an integrated trispectrum that only depends on four $k$-modes moduli. We model and measure the matter i-trispectrum from a set of 5000 \textsc{Quijote} N-body simulations both in real and redshift space, finding good agreement between simulations outputs and model up to mildly non-linear scales. Using the power spectrum, bispectrum and i-trispectrum joint data-vector covariance matrix estimated from the simulations, we begin to quantify the added-value provided by the i-trispectrum. In particular, we forecast the i-trispectrum improvements on constraints on the local primordial non-Gaussianity amplitude parameters $f_\mathrm{nl}$ and $g_\mathrm{nl}$. For example, using the full joint data-vector, we forecast $f_\mathrm{nl}$ constraints up to two times ($\sim32\%$) smaller in real (redshift) space than those obtained without i-trispectrum.
description: accepted: 6th of November 2020, published: 11th of January 2021 , 64 pages (35 pages for the main text), 15 figures
Power, people, places and spaces: examining the politics of participation across scales of resource governance
Creators: name: Adeyeye, Yemi Olaonipekun
Publisher: name: University of British Columbia
Year: 2020

description: Identifying suitable approaches for designing and implementing participatory processes in ways that enhance the delivery of outcomes, including community access to forest and water benefits, remains a key societal challenge. Central to this challenge are complexities related to structuring the participation of diverse actors operating at different governance scales and with diverse objectives. Prior studies have recognized that local communities and Indigenous Peoples are most affected by policy actions, and thus should meaningfully participate in policy debates at the regional and national and international scales. Yet participatory processes across governance scales tend to favor the participation of powerful actors including government representatives while limiting the participation of local communities and Indigenous Peoples. This study examines the scalar and participatory aspect of resource governance through two study contexts – the World Conservation Congress 2016 and the Reciprocal Water Agreement in Bolivia. Using qualitative data collection methods including semi-structured interviews, participant observation and document analysis, I examined how longstanding and emerging institutions and institutional arrangements that seek to integrate the participation of diverse actors at the regional and national and international scales, shape local participation and access to resources benefits. I developed a typology of participation to consider the linkages between gradations of participation based on different levels of power and spaces where the participation is likely to occur. Across the two study contexts, findings suggest that both longstanding and emerging institutions and institutional arrangements have the tendency to reinforce prevailing power relations. This in turn results in unequal participation among actors. Additionally, findings highlight the implications of existing gaps in governance on perceptions among actors about participation in resource decision-making. Overall, this study makes visible how prevailing and uneven structures of power across governance scales shape dominant visions for resource governance and the nature of participation of local communities and Indigenous Peoples in resource decision-making. Finally, this study identifies key recommendations for ensuring that adequate participation of local actors are addressed in resource governance. These include participatory design of spaces with local or Indigenous leadership, coordinated policy actions across sectors with overlapping responsibilities and objectives and locally-sourced and managed financial support.
Characteristic varieties of quasi-projective manifolds and orbifolds
Creators: name: Bartolo, Enrique Artal
name: Cogolludo-Agustin, Jose Ignacio
name: Matei, Daniel
Publisher: name: arXiv
Year: 2010
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 58K65, 32S20, 32S50 (Primary) 14B05, 14H30, 14H50 (Secondary)

description: We prove that the irreducible components of the characteristic varieties of quasi-projective manifolds are either pull-backs of such components for orbifolds, or torsion points. This gives an interpretation for the so-called \emph{translated} components of the characteristic varieties, and shows that the zero-dimensional components are indeed torsion. The main result is used to derive further obstructions for a group to be the fundamental group of a quasi-projective manifold.
description: 33 pages, no figures. General rearrangement and proof of Proposition 4.2 is expanded
FFT-LB modeling of thermal liquid-vapor systems
Creators: name: Gan, Yanbiao
name: Xu, Aiguo
name: Zhang, Guangcai
name: Li, Yingjun
Publisher: name: arXiv
Year: 2010
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Cellular Automata and Lattice Gases (nlin.CG)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We further develop a thermal LB model for multiphase flows. In the improved model, we propose to use the FFT scheme to calculate both the convection term and external force term. The usage of FFT scheme is detailed and analyzed. By using the FFT algorithm spatiotemporal discretization errors are decreased dramatically and the conservation of total energy is much better preserved. A direct consequence of the improvement is that the unphysical spurious velocities at the interfacial regions can be damped to neglectable scale. Together with the better conservation of total energy, the more accurate flow velocities lead to the more accurate temperature field which determines the dynamical and final states of the system. With the new model, the phase diagram of the liquid-vapor system obtained from simulation is more consistent with that from theoretical calculation. Very sharp interfaces can be achieved. The accuracy of simulation results are also verified by the Laplace law. The FFT scheme can be easily applied to other models for multiphase flows.
description: 34 pages, 21 figures
Tracing the cellular basis of islet specification in mouse pancreas
Creators: name: Sznurkowska, Magdalena K.
name: Hannezo, Edouard
name: Azzarelli, Roberta
name: Chatzeli, Lemonia
name: Ikeda, Tatsuro
name: Yoshida, Shosei
name: Philpott, Anna
name: Simons, Benjamin D.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/114/2397
/631/136/142
/631/136/2060
/13/51
/14/19
/14/63
/64/60
article

description: Abstract: Pancreatic islets play an essential role in regulating blood glucose level. Although the molecular pathways underlying islet cell differentiation are beginning to be resolved, the cellular basis of islet morphogenesis and fate allocation remain unclear. By combining unbiased and targeted lineage tracing, we address the events leading to islet formation in the mouse. From the statistical analysis of clones induced at multiple embryonic timepoints, here we show that, during the secondary transition, islet formation involves the aggregation of multiple equipotent endocrine progenitors that transition from a phase of stochastic amplification by cell division into a phase of sublineage restriction and limited islet fission. Together, these results explain quantitatively the heterogeneous size distribution and degree of polyclonality of maturing islets, as well as dispersion of progenitors within and between islets. Further, our results show that, during the secondary transition, α- and β-cells are generated in a contemporary manner. Together, these findings provide insight into the cellular basis of islet development.
title: Ð¤ÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ðµ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ðµ Ð³Ð¸Ð´ÑÐ°Ð²Ð»Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð¼Ð¾ÑÑÐ¸ Ð¸ Ð²Ð¾Ð´Ð¾ÑÐ´ÐµÑÐ¶Ð¸Ð²Ð°ÑÑÐµÐ¹ ÑÐ¿Ð¾ÑÐ¾Ð±Ð½Ð¾ÑÑÐ¸ Ð¿Ð¾ÑÐ²Ð¾-Ð³ÑÑÐ½ÑÐ° Ð¿ÑÐ¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð³Ð¸Ð´ÑÐ¾Ð³ÐµÐ¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ñ ÑÑÐ»Ð¾Ð²Ð¸Ð¹ ÑÐµÑÑÐ¸ÑÐ¾ÑÐ¸Ð¸ ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ð°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Functional description of hydraulic conductivity and soil water-retention capacity in the study of construction site hydrogeological conditions
Creators: name: ÐÐ¸Ð½ÐµÐ²ÑÐºÐ¸Ð¹, Ð Ð¾Ð¼Ð°Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: Ð¿Ð¾ÑÐ²Ð¾-Ð³ÑÑÐ½Ñ
Ð²Ð¾Ð´Ð¾ÑÐ´ÐµÑÐ¶Ð¸Ð²Ð°ÑÑÐ°Ñ ÑÐ¿Ð¾ÑÐ¾Ð±Ð½Ð¾ÑÑÑ
Ð³Ð¸Ð´ÑÐ°Ð²Ð»Ð¸ÑÐµÑÐºÐ°Ñ Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð¼Ð¾ÑÑÑ
Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
soil
water retention capacity
hydraulic conductivity
mathematical modeling

description: Ð ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð¾ ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¸ Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð½Ð¾Ðµ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ðµ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ðµ Ð²Ð¾Ð´Ð¾ÑÐ´ÐµÑÐ¶Ð¸Ð²Ð°ÑÑÐµÐ¹ ÑÐ¿Ð¾ÑÐ¾Ð±Ð½Ð¾ÑÑÐ¸ Ð¸ Ð³Ð¸Ð´ÑÐ°Ð²Ð»Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð¼Ð¾ÑÑÐ¸ Ð¿Ð¾ÑÐ²Ð¾-Ð³ÑÑÐ½ÑÐ° Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸ÐµÐ¼ Ð¾Ð±ÑÐ¸Ñ Ð¸Ð½ÑÐµÑÐ¿ÑÐµÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð², Ð° ÑÐ°ÐºÐ¶Ðµ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð° Ð²ÐµÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ñ Ð´Ð°Ð½Ð½Ð¾Ð³Ð¾ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ñ Ð½Ð° Ð¾Ð±ÑÐµÐºÑÐ°Ñ (Ð¿Ð¾ÑÐ²Ð°Ñ, Ð³ÑÑÐ½ÑÐ°Ñ) ÑÐ°Ð·Ð»Ð¸ÑÐ½Ð¾Ð³Ð¾ Ð³ÑÐ°Ð½ÑÐ»Ð¾Ð¼ÐµÑÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¾ÑÑÐ°Ð²Ð°. ÐÑÐ¸ ÑÑÐ¾Ð¼ Ð±ÑÐ»Ð¾ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¾ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ñ Ñ Ð°Ð½Ð°Ð»Ð¾Ð³Ð¸ÑÐ½ÑÐ¼Ð¸ ÑÑÐ½ÐºÑÐ¸ÑÐ¼Ð¸ Ð¸Ð· Ð»Ð¸ÑÐµÑÐ°ÑÑÑÐ½ÑÑ Ð¸ÑÑÐ¾ÑÐ½Ð¸ÐºÐ¾Ð².
description: The paper proposes a physically justified functional description of the water retention capacity and hydraulic conductivity of the soil with the use of common interpreted parameters, as well as verification of this description on objects (soils) with different texture. In this case, a comparison was made of the proposed functional description with similar functions from literary sources.
Cutoff thermalization for Ornstein-Uhlenbeck systems with small Lévy noise in the Wasserstein distance
Creators: name: Barrera, Gerardo
name: Högele, Michael A.
name: Pardo, Juan Carlos
Publisher: name: arXiv
Year: 2020
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 37H10, 60J60, 60J70, 60G51

description: This article establishes cutoff thermalization (also known as the cutoff phenomenon) for a class of generalized Ornstein-Uhlenbeck systems $(X^\varepsilon_t(x))_{t\geqslant 0}$ with $\varepsilon$-small additive Lévy noise and initial value $x$. The driving noise processes include Brownian motion, $α$-stable Lévy flights, finite intensity compound Poisson processes, and red noises, and may be highly degenerate. Window cutoff thermalization is shown under mild generic assumptions; that is, we see an asymptotically sharp $\infty/0$-collapse of the renormalized Wasserstein distance from the current state to the equilibrium measure $μ^\varepsilon$ along a time window centered on a precise $\varepsilon$- and $x$-dependent time scale $t_\varepsilon^x$. In many interesting situations such as reversible (Lévy) diffusions it is possible to prove the existence of an explicit, universal, deterministic cutoff thermalization profile. That is, for generic initial data $x$ we obtain the stronger result $\mathcal{W}_p(X^\varepsilon_{t_\varepsilon + r}(x), μ^\varepsilon) \cdot \varepsilon^{-1} \rightarrow K\cdot e^{-q r}$ as $\varepsilon \rightarrow 0$ for any $r\in \mathbb{R}$, some spectral constants $K, q>0$ and any $p\geqslant 1$ whenever the distance is finite. The existence of this limit is characterized by the absence of non-normal growth patterns in terms of an orthogonality condition on a computable family of generalized eigenvectors of $\mathcal{Q}$. Precise error bounds are given. Using these results, this article provides a complete discussion of the cutoff phenomenon for the classical linear oscillator with friction subject to $\varepsilon$-small Brownian motion or $α$-stable Lévy flights. Furthermore, we cover the highly degenerate case of a linear chain of oscillators in a generalized heat bath at low temperature.
description: 47 pages
Spin transport in higher n-acene molecules
Creators: name: Pilevarshahri, R.
name: Rungger, I.
name: Archer, T.
name: Sanvito, S.
name: Shahtahmasebi, N.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the spin transport properties of molecules belonging to the acenes series by using density functional theory combined with the non-equilibrium Green's function approach to electronic transport. While short acenes are found to be non-magnetic, molecules comprising more than nine acene rings have a spin-polarized ground state. In their gas phase these have a singlet total spin configuration, since the two unpaired electrons occupying the doubly degenerate highest molecular orbital are antiferromagnetically coupled to each other. Such an orbital degeneracy is however lifted once the molecule is attached asymmetrically to Au electrodes via thiol linkers, leading to a fractional magnetic moment. In this situation the system Au/n-acene/Au can act as an efficient spin-filter with interesting applications in the emerging field of organic spintronics.
description: 13 pages,9 figures
No-arbitrage of second kind in countable markets with proportional transaction costs
Creators: name: Bouchard, Bruno
name: Taflin, Erik
Publisher: name: arXiv
Year: 2010
Subjects: subject: Computational Finance (q-fin.CP)
subject: Probability (math.PR)
subject: Pricing of Securities (q-fin.PR)
subject: FOS: Economics and business
subject: FOS: Mathematics

description: Motivated by applications to bond markets, we propose a multivariate framework for discrete time financial markets with proportional transaction costs and a countable infinite number of tradable assets. We show that the no-arbitrage of second kind property (NA2 in short), recently introduced by Rasonyi for finite-dimensional markets, allows us to provide a closure property for the set of attainable claims in a very natural way, under a suitable efficient friction condition. We also extend to this context the equivalence between NA2 and the existence of many (strictly) consistent price systems.
description: Published in at http://dx.doi.org/10.1214/11-AAP825 the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Contribuição para o estudo da mineralogia do plutonito de Vila Nova, Centro de Portugal: micas
Creators: name: Silva, Maria Manuela V. G.
name: Rei, Ana Isabel M.
Publisher: name: Zenodo
Year: 2020

description: O plutonito granítico de Vila Nova, de 542+0,8 Ma, aflora na região centro de Portugal, possui grão médio, duas micas, é peraluminoso, contém grande quantidade de encraves sobremicáceos, na maioria milimétricos, mas alguns maiores e que possuem andaluzite, silimanite e Zn-hercinite. O plutão provocou auréola de corneanas. Apresenta-se afectado por intensa deformação dúctil e frágil e muito meteorizado. As micas do granitoide e dos encraves são classificadas como micas da série da biotite e como moscovites. As micas da série da biotite dos encraves possuem mais Fe3+, Fe2+, Li, M, Rb, Cl e OH e menos SiO2, Al2O3, VIAl, K, I, F e XMg do as do granitoide, mas a moscovite possui composição semelhante. As biotites são relíquias metastáveis, tendo cristalizado a pressões características da crusta média. Os encraves são restitos do protólito que originou o magma granitoide e equilibram-se a temperaturas da ordem de 700-760 ºC. As moscovites são primárias/magmáticas e secundárias, sendo as primárias significativamente mais ricas em paragonite, VIAl, tAl, Na e mais pobres em celadonite, Fe, Mg e M. A presença e B, F, Rb, Li, Cs no magma permitiu a cristalização da moscovite magmática. A moscovite secundária mais rica em Si (apfu) e componentes octaédricos cristalizou mais tardiamente, mas a pressão mais elevada, durante a deformação dúctil varisca, que afetou o granitoide.
Mapping epigenetic divergence in the massive radiation of Lake Malawi cichlid fishes
Creators: name: Vernaz, Grégoire
name: Malinsky, Milan
name: Svardal, Hannes
name: Du, Mingliu
name: Tyers, Alexandra M.
name: Santos, M. Emília
name: Durbin, Richard
name: Genner, Martin J.
name: Turner, George F.
name: Miska, Eric A.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Article
/631/181/2474
/631/181/735
/631/208/177
/631/208/514/1948
/38/39
/45
/45/91
/45/23
/45/22
/49
/49/91
/49/23
/64
article

description: Abstract: Epigenetic variation modulates gene expression and can be heritable. However, knowledge of the contribution of epigenetic divergence to adaptive diversification in nature remains limited. The massive evolutionary radiation of Lake Malawi cichlid fishes displaying extensive phenotypic diversity despite extremely low sequence divergence is an excellent system to study the epigenomic contribution to adaptation. Here, we present a comparative genome-wide methylome and transcriptome study, focussing on liver and muscle tissues in phenotypically divergent cichlid species. In both tissues we find substantial methylome divergence among species. Differentially methylated regions (DMR), enriched in evolutionary young transposons, are associated with transcription changes of ecologically-relevant genes related to energy expenditure and lipid metabolism, pointing to a link between dietary ecology and methylome divergence. Unexpectedly, half of all species-specific DMRs are shared across tissues and are enriched in developmental genes, likely reflecting distinct epigenetic developmental programmes. Our study reveals substantial methylome divergence in closely-related cichlid fishes and represents a resource to study the role of epigenetics in species diversification.
Computing Lengths of Non-Crossing Shortest Paths in Planar Graphs
Creators: name: Balzotti, Lorenzo
name: Franciosa, Paolo G.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences
subject: F.2.2; G.2.2

description: Given a plane undirected graph $G$ with non-negative edge weights and a set of $k$ terminal pairs on the external face, it is shown in Takahashi et al. (Algorithmica, 16, 1996, pp. 339-357) that the union $U$ of $k$ non-crossing shortest paths joining the $k$ terminal pairs (if they exist) can be computed in $O(n\log n)$ time, where $n$ is the number of vertices of $G$. In the restricted case in which the union $U$ of the shortest paths is a forest, it is also shown that their lengths can be computed in the same time bound. We show in this paper that it is always possible to compute the lengths of $k$ non-crossing shortest paths joining the $k$ terminal pairs in linear time, once the shortest paths union $U$ has been computed, also in the case $U$ contains cycles. Moreover, each shortest path $π$ can be listed in $O(\max\{\ell, \ell \log\frac{k}{\ell} \})$, where $\ell$ is the number of edges in $π$. As a consequence, the problem of computing non-crossing shortest paths and their lengths in a plane undirected weighted graph can be solved in $O(n\log k)$ time in the general case.
description: 15 pages, 11 figures
RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin
Creators: name: Bandiera, Roberto
name: Wagner, Rebecca E.
name: Britto-Borges, Thiago
name: Dieterich, Christoph
name: Dietmann, Sabine
name: Bornelöv, Susanne
name: Frye, Michaela
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Article
/631/45/500
/631/80
/631/532/2438
/13
/13/106
/13/89
/38/47
/38/77
/42
/42/109
/45
/45/15
/45/91
article

description: Abstract: Pausing of RNA polymerase II (Pol II) close to promoters is a common regulatory step in RNA synthesis, and is coordinated by a ribonucleoprotein complex scaffolded by the noncoding RNA RN7SK. The function of RN7SK-regulated gene transcription in adult tissue homoeostasis is currently unknown. Here, we deplete RN7SK during mouse and human epidermal stem cell differentiation. Unexpectedly, loss of this small nuclear RNA specifically reduces transcription of numerous cell cycle regulators leading to cell cycle exit and differentiation. Mechanistically, we show that RN7SK is required for efficient transcription of highly expressed gene pairs with bidirectional promoters, which in the epidermis co-regulated cell cycle and chromosome organization. The reduction in transcription involves impaired splicing and RNA decay, but occurs in the absence of chromatin remodelling at promoters and putative enhancers. Thus, RN7SK is directly required for efficient Pol II transcription of highly transcribed bidirectional gene pairs, and thereby exerts tissue-specific functions, such as maintaining a cycling cell population in the epidermis.
Centralizers in $\widetilde A_2$ groups
Creators: name: Robertson, Guyan
Publisher: name: arXiv
Year: 2011
Subjects: subject: Group Theory (math.GR)
subject: Metric Geometry (math.MG)
subject: FOS: Mathematics
subject: 20F67, 51E24

description: Let $Γ$ be a torsion free discrete group acting cocompactly on a two dimensional euclidean building $Δ$. The centralizer of an element of $Γ$ is either a Bieberbach group or is described by a finite graph of finite cyclic groups. Explicit examples are computed, with $Δ$ of type $\widetilde A_2$.
Brain metabolic changes across King’s stages in amyotrophic lateral sclerosis: a 18 F-2-fluoro-2-deoxy- d -glucose-positron emission tomography study
Creators: name: Canosa, Antonio
name: Calvo, Andrea
name: Moglia, Cristina
name: Manera, Umberto
name: Vasta, Rosario
name: Di Pede, Francesca
name: Cabras, Sara
name: Nardo, Davide
name: Arena, Vincenzo
name: Grassano, Maurizio
name: D’Ovidio, Fabrizio
name: Van Laere, Koen
name: Van Damme, Philip
name: Pagani, Marco
name: Chiò, Adriano
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Original Article
Neurology
Amyotrophic lateral sclerosis
18F-FDG-PET
King’s staging system

description: Abstract: Purpose: To assess the brain metabolic correlates of the different regional extent of ALS, evaluated with the King’s staging system, using brain 18F-2-fluoro-2-deoxy-d-glucose-PET (18F-FDG-PET). Methods: Three hundred ninety ALS cases with King’s stages 1, 2, and 3 (n = 390), i.e., involvement of 1, 2, and 3 body regions respectively, underwent brain 18F-FDG-PET at diagnosis. King’s stage at PET was derived from ALSFRS-R and was regressed out against whole-brain metabolism in the whole sample. The full factorial design confirmed the hypothesis that differences among groups (King’s 1, King’s 2, King’s 3, and 40 healthy controls (HC)) existed overall. Comparisons among stages and between each group and HC were performed. We included age at PET and sex as covariates. Results: Brain metabolism was inversely correlated with stage in medial frontal gyrus bilaterally, and right precentral and postcentral gyri. The full factorial design resulted in a significant main effect of groups. There was no significant difference between stages 1 and 2. Comparing stage 3 to stage 1+2, a significant relative hypometabolism was highlighted in the former in the left precentral and medial frontal gyri, and in the right medial frontal, postcentral, precentral, and middle frontal gyri. The comparisons between each group and HC showed the extension of frontal metabolic changes from stage 1 to stage 3, with the larger metabolic gap between stages 2 and 3. Conclusions: Our findings support the hypothesis that in ALS, the propagation of neurodegeneration follows a corticofugal, regional ordered pattern, extending from the motor cortex to posterior and anterior regions.
Directed harmonic currents near non-hyperbolic linearized singularities
Creators: name: Chen, Zhangchi
Publisher: name: arXiv
Year: 2020
Subjects: subject: Dynamical Systems (math.DS)
subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: 32M25, 32S65, 32C30, 53C65

description: Let $(\mathbb{D}^2,\mathcal{F},\{0\})$ be a singular holomorphic foliation on the unit bidisc $\mathbb{D}^2$ defined by the linear vector field \[ z \,\frac{\partial}{\partial z}+ λ\,w \,\frac{\partial}{\partial w}, \] where $λ\in\mathbb{C}^*$. Such a foliation has a non-degenerate linearized singularity at $0$. Let $T$ be a harmonic current directed by $\mathcal{F}$ which does not give mass to any of the two separatrices $(z=0)$ and $(w=0)$ and whose the trivial extension $\tilde{T}$ across $0$ is $dd^c$-closed. The Lelong number of $T$ at $0$ describes the mass distribution on the foliated space. In 2014 Nguyen proved that when $λ\notin\mathbb{R}$, i.e. $0$ is a hyperbolic singularity, the Lelong number at $0$ vanishes. For the non-hyperbolic case $λ\in\mathbb{R}^*$ the article proves the following results. The Lelong number at $0$: 1) is strictly positive if $λ>0$; 2) vanishes if $λ\in\mathbb{Q}_{<0}$; 3) vanishes if $λ<0$ and $T$ is invariant under the action of some cofinite subgroup of the monodromy group.
description: 24 pages, 15 figures
Bayesian clustering in decomposable graphs
Creators: name: Bornn, Luke
name: Caron, François
Publisher: name: arXiv
Year: 2010
Subjects: subject: Methodology (stat.ME)
subject: Applications (stat.AP)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: In this paper we propose a class of prior distributions on decomposable graphs, allowing for improved modeling flexibility. While existing methods solely penalize the number of edges, the proposed work empowers practitioners to control clustering, level of separation, and other features of the graph. Emphasis is placed on a particular prior distribution which derives its motivation from the class of product partition models; the properties of this prior relative to existing priors is examined through theory and simulation. We then demonstrate the use of graphical models in the field of agriculture, showing how the proposed prior distribution alleviates the inflexibility of previous approaches in properly modeling the interactions between the yield of different crop varieties.
description: 3 figures, 1 table
The risk of cardiovascular disease in women after miscarriage, stillbirth, and therapeutic abortion: a protocol for a systematic review and meta-analysis
Creators: name: Muehlschlegel, Charlotte
name: Kyriacou, Harry
name: Al-Mohammad, Abdulrahman
name: Foster-Davies, Lowri A.
name: Simmons-Jones, Fiona
name: Oliver-Williams, Clare
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Protocol
Miscarriage
Stillbirth
Abortion
Cardiovascular disease
Coronary heart disease
Stroke
Systematic review
Meta-analysis

description: Funder: Homerton College, University of Cambridge (GB)
description: Funder: National Institute for Health Research; doi: http://dx.doi.org/10.13039/501100000272
description: Abstract: Background: Cardiovascular disease (CVD) is the leading cause of death in women, responsible for approximately a third of all female deaths. Pregnancy complications are known to be associated with a greater risk of incident CVD in mothers. However, the relationships between pregnancy loss due to miscarriage, stillbirth, or therapeutic abortion, and future maternal cardiovascular health are under-researched. This study seeks to provide an up-to-date systematic review and meta-analysis of the relationship between these three forms of pregnancy loss and the subsequent development of CVD. Methods: This systematic review will follow the Preferred Reporting Items for Systematic Review and Meta-Analysis checklist (PRISMA) and the Meta-analyses Of Observational Studies in Epidemiology (MOOSE) Checklist. A systematic search will be undertaken using publications identified in MEDLINE (PubMed), Scopus, Web of Knowledge, the CINAHL Nursing Database, and the Cochrane Library. The eligibility of each publication will be determined by predefined selection criteria. The quality of the included studies will be rated using the Newcastle-Ottawa Scale. Pooled measures of association will be computed using random-effects model meta-analyses. Between-study heterogeneity will be assessed using the I2 statistic and the Cochrane χ2 statistic. Small study effects will be evaluated for meta-analyses with sufficient studies through the use of funnel plots and Egger’s test. Discussion: The results of this systematic review will discuss the long-term risks of multiple types of cardiovascular disease in women who have experienced miscarriage, stillbirth, and/or therapeutic abortion. It will contribute to the growing field of cardio-obstetrics as the first to consider the full breadth of literature regarding the association between all forms of pregnancy loss and future maternal cardiovascular disease. Systematic review registration: PROSPERO registration number [CRD42020167587]
Still, they are speaking
Creators: name: Trim, Alison
Publisher: name: University of British Columbia
Year: 2020

description: Still, they are speaking is an exhibition and accompanying written paper, that uses expanded drawing practices developed in and with post-fire landscapes of the Okanagan valley to explore the role of drawing in enabling somatic engagement with land and the non-human. My thesis evolved from an initial enquiry into how a move from Ireland to this new environment would impact my drawing practice. A methodology of regular walking on the outskirts of Kelowna, in the region of the 2003 Okanagan mountain fire, established a somatic relationship with specific place. Creative research taking place in the field led me to explore the different forms of knowledge we encounter through physical presence in the land, and to consider ways in which drawing can bridge the gap between human and non-human knowledges. The clear physical traces of the movement of fire through this land, particularly evident in the bark of trees, culminated in approaches to site-specific mark-making that actively engaged with surface, and led me to consider drawing as wake, a trace of past movement, a story left behind. Equating physical marks in land as forms of knowledge brought me to an exploration of written language as a mark making practice informed by the natural world, a theme that is explored by the writing of David Abrams and Tim Ingold. With wildfire an ongoing environmental issue within the Okanagan specifically and British Columbia as a whole, I have used my drawing practice as a tool to bring the physical marks of wildfire still written in the land into the cultural, conversational space of the gallery. In this exhibition drawing becomes a process through which human understanding can engage in productive communication with the physical language of the land. Through a combination of field and studio work initial drawing experiments developed into large-scale installations occupying a physical presence in the gallery that allows mark and surface to speak.
The cutoff phenomenon in total variation for nonlinear Langevin systems with small layered stable noise
Creators: name: Barrera, G.
name: Högele, Michael A.
name: Pardo, J. C.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 37A25, 37A30, 60F05, 60G51, 60G52, 65C30

description: This paper provides an extended case study of the cutoff phenomenon for a prototypical class of nonlinear Langevin systems with a single stable state perturbed by an additive pure jump Lévy noise of small amplitude $\varepsilon>0$, where the driving noise process is of layered stable type. Under a drift coercivity condition the associated family of processes $X^\varepsilon$ turns out to be exponentially ergodic with equilibrium distribution $μ^{\varepsilon}$ in total variation distance which extends a result from Peng and Zhang (2018) to arbitrary polynomial moments. The main results establish the cutoff phenomenon with respect to the total variation, under a sufficient smoothing condition of Blumenthal-Getoor index $α>3/2$. That is to say, in this setting we identify a deterministic time scale $\mathfrak{t}_{\varepsilon}^{\mathrm{cut}}$ satisfying $\mathfrak{t}_ \varepsilon^{\mathrm{cut}} \rightarrow \infty$, as $\varepsilon \rightarrow 0$, and a respective time window, $\mathfrak{t}_\varepsilon^{\mathrm{cut}} \pm o(\mathfrak{t}_\varepsilon^{\mathrm{cut}})$, during which the total variation distance between the current state and its equilibrium $μ^{\varepsilon}$ essentially collapses as $\varepsilon$ tends to zero. In addition, we extend the dynamical characterization under which the latter phenomenon can be described by the convergence of such distance to a unique profile function first established in Barrera and Jara (2020) to the Lévy case for nonlinear drift. This leads to sufficient conditions, which can be verified in examples, such as gradient systems subject to small symmetric $α$-stable noise for $α>3/2$. The proof techniques differ completely from the Gaussian case due to the absence of respective Girsanov transforms which couple the nonlinear equation and the linear approximation asymptotically even for short times.
description: 68p
Non-universal shear viscosity from Einstein gravity
Creators: name: Erdmenger, Johanna
name: Kerner, Patrick
name: Zeller, Hansjörg
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: A very famous result of gauge/gravity duality is the universality of the ratio of shear viscosity to entropy density in every field theory holographically dual to classical, two-derivative (Einstein) gravity. We present a way to obtain deviation form this universality by breaking the rotational symmetry spontaneously. In anisotropic fluids additional shear modes exist and their corresponding shear viscosities may be non-universal. We confirm this by explicitly calculating the shear viscosities in a transversely isotropic background, a p-wave superfluid, and study its critical behavior. This is a first decisive step towards further applications of gauge/gravity duality to physical systems.
description: 11 pages, 2 figures. v2: small corrections
title: ÐÐ±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ðµ Ð¿ÑÐ¾ÑÐ½Ð¾ÑÑÐ½Ð¾Ð¹ Ð½Ð°Ð´ÐµÐ¶Ð½Ð¾ÑÑÐ¸ ÑÐ¾ÑÐ¾ÑÐ° Ð¿Ð°ÑÐ¾Ð²Ð¾Ð¹ ÑÑÑÐ±Ð¸Ð½Ñ ÐºÐ¾Ð¼Ð±Ð¸Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð¹ ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐ¸
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Ensuring the strength reliability of the steam turbine rotor of a combined power plant.
Creators: name: Ð¨Ð°Ð±Ð°Ð¹Ð»Ð¾Ð², Ð¡ÐµÑÐ³ÐµÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: ÐÐ°ÑÐ¾Ð²ÑÐµ ÑÑÑÐ±Ð¸Ð½Ñ
Ð Ð¾ÑÐ¾ÑÑ
ÐÐ°ÑÐ¾Ð³Ð°Ð·Ð¾Ð²ÑÐµ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐ¸
ÐÐ¾Ð´ÑÐ¸Ð¿Ð½Ð¸ÐºÐ¸
ÑÐ°ÑÑÐµÑ Ð¿Ð¾Ð»Ð·ÑÑÐµÑÑÐ¸
ÑÐµÐ»Ð°ÐºÑÐ°ÑÐ¸Ñ Ð½Ð°Ð¿ÑÑÐ¶ÐµÐ½Ð¸Ð¹
ÑÐ¿Ð¾ÑÐ½ÑÐµ Ð¿Ð¾Ð´ÑÐ¸Ð¿Ð½Ð¸ÐºÐ¸
ÑÐ°ÑÑÐµÑ Ð¾ÑÐµÐ²ÑÑ ÑÑÐ¸Ð»Ð¸Ð¹
creep calculation
stress relaxation
thrust bearing
axial force calculation

description: ÐÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ ÑÐ°ÑÑÐµÑ ÑÐµÐ¿Ð»Ð¾Ð²Ð¾Ð¹ ÑÑÐµÐ¼Ñ ÐÐÐ£, ÑÐ°ÑÑÐµÑ Ð¿Ð°ÑÐ¾Ð²Ð¾Ð¹ ÑÑÑÐ±Ð¸Ð½Ñ Ð¢-50/64-7,4/0,12 , ÐºÐ¾ÑÐ¾ÑÑÐ¹ Ð²ÐºÐ»ÑÑÐ°ÐµÑ Ð² ÑÐµÐ±Ñ ÑÐµÐ¿Ð»Ð¾Ð²Ð¾Ð¹ ÑÐ°ÑÑÐµÑ Ð¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð¾ÑÐ½ÑÐ¹ ÑÐ°ÑÑÐµÑ, Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½ ÑÐµÐ¿Ð»Ð¾Ð²Ð¾Ð¹ ÑÐ°ÑÑÐµÑ ÑÐ¾ÑÐ¾ÑÐ° Ð¿Ð°ÑÐ¾Ð²Ð¾Ð¹ ÑÑÑÐ±Ð¸Ð½Ñ Ñ ÑÐ°Ð·Ð½ÑÐ¼Ð¸ Ð³ÑÐ°Ð½Ð¸ÑÐ½ÑÐ¼Ð¸ ÑÑÐ»Ð¾Ð²Ð¸ÑÐ¼Ð¸, ÑÐ°ÑÑÐµÑ Ð½Ð°Ð¿ÑÑÐ¶ÐµÐ½Ð¸Ð¹ Ð² ÑÐ¾ÑÐ¾ÑÐµ, ÑÐ°ÑÑÐµÑ ÑÐµÐ»Ð°ÐºÑÐ°ÑÐ¸Ð¸ Ð½Ð°Ð¿ÑÑÐ¶ÐµÐ½Ð¸Ð¹, ÑÐ°ÑÑÐµÑ Ð¿Ð¾Ð»Ð·ÑÑÐµÑÑÐ¸ Ð¼ÐµÑÐ°Ð»Ð»Ð° ÑÐ¾ÑÐ¾ÑÐ°, Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½ Ð²Ð°ÑÐ¸Ð°Ð½Ñ Ð¼Ð¾Ð´ÐµÑÐ½Ð¸Ð·Ð°ÑÐ¸Ð¸ ÑÐ¾ÑÐ¾ÑÐ° Ð´Ð»Ñ Ð¿ÑÐ¾Ð´Ð»ÐµÐ½Ð¸Ñ ÑÐµÑÑÑÑÐ°, ÑÐ´ÐµÐ»Ð°Ð½ ÑÐ°ÑÑÐµÑ Ð¾ÑÐµÐ²ÑÑ ÑÑÐ¸Ð»Ð¸Ð¹ Ð¸ ÑÐ°ÑÑÐµÑ ÑÐ¿Ð¾ÑÐ½Ð¾Ð³Ð¾ Ð¿Ð¾Ð´ÑÐ¸Ð¿Ð½Ð¸ÐºÐ°, Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ ÑÑÐ°Ð²Ð½Ð¸ÑÐµÐ»ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¼ÐµÑÐ¾Ð´Ð° ÐºÐ¾Ð½ÐµÑÐ½ÑÑ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð² Ð¸ Ð¼ÐµÑÐ¾Ð´Ð° ÑÑÐ¿ÐµÑ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð².
description: The calculation of the thermal scheme of the CCGT, the calculation of the steam turbine T-50/64-7,4/0,12 which includes the thermal calculation and design calculation, the thermal calculation of the steam turbine rotor with different boundary conditions, the calculation of stresses in the rotor, the calculation of stress relaxation, the calculation of the creep of the rotor metal, the option of upgrading the rotor to extend the service life, the calculation of axial forces and the calculation of the thrust bearing, a comparative analysis of the finite element method and the super element method is presented.
Mixture decompositions of exponential families using a decomposition of their sample spaces
Creators: name: Montufar, Guido
Publisher: name: arXiv
Year: 2010
Subjects: subject: Statistics Theory (math.ST)
subject: Machine Learning (stat.ML)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 52B05, 60C05, 62E17

description: We study the problem of finding the smallest $m$ such that every element of an exponential family can be written as a mixture of $m$ elements of another exponential family. We propose an approach based on coverings and packings of the face lattice of the corresponding convex support polytopes and results from coding theory. We show that $m=q^{N-1}$ is the smallest number for which any distribution of $N$ $q$-ary variables can be written as mixture of $m$ independent $q$-ary variables. Furthermore, we show that any distribution of $N$ binary variables is a mixture of $m = 2^{N-(k+1)}(1+ 1/(2^k-1))$ elements of the $k$-interaction exponential family.
description: 17 pages, 2 figures
Analysis of Plasmodium vivax schizont transcriptomes from field isolates reveals heterogeneity of expression of genes involved in host-parasite interactions
Creators: name: Siegel, Sasha V.
name: Chappell, Lia
name: Hostetler, Jessica B.
name: Amaratunga, Chanaki
name: Suon, Seila
name: Böhme, Ulrike
name: Berriman, Matthew
name: Fairhurst, Rick M.
name: Rayner, Julian C.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/326/417
/631/326/417/2551
/631/208/199
article

description: Funder: Division of Intramural Research, National Institute of Allergy and Infectious Diseases; doi: http://dx.doi.org/10.13039/100006492
description: Abstract: Plasmodium vivax gene regulation remains difficult to study due to the lack of a robust in vitro culture method, low parasite densities in peripheral circulation and asynchronous parasite development. We adapted an RNA-seq protocol “DAFT-seq” to sequence the transcriptome of four P. vivax field isolates that were cultured for a short period ex vivo before using a density gradient for schizont enrichment. Transcription was detected from 78% of the PvP01 reference genome, despite being schizont-enriched samples. This extensive data was used to define thousands of 5′ and 3′ untranslated regions, some of which overlapped with neighbouring transcripts, and to improve the gene models of 352 genes, including identifying 20 novel gene transcripts. This dataset has also significantly increased the known amount of heterogeneity between P. vivax schizont transcriptomes from individual patients. The majority of genes found to be differentially expressed between the isolates lack Plasmodium falciparum homologs and are predicted to be involved in host-parasite interactions, with an enrichment in reticulocyte binding proteins, merozoite surface proteins and exported proteins with unknown function. An improved understanding of the diversity within P. vivax transcriptomes will be essential for the prioritisation of novel vaccine targets.
title: ÐÐ¸Ð½Ð°Ð¼Ð¸ÐºÐ° ÑÐµÐ±ÐµÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÐ¸ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸Ñ-ÑÑÑÑÐ° ÐÐÐÐ° Ð² 21-Ð¾Ð¼ Ð²ÐµÐºÐµ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Dynamics of the cost of raw aluminum kazain the 21st century
Creators: name: Ð§ÑÐºÐ°Ð½Ð¾Ð², ÐÐ½Ð´ÑÐµÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2023
Subjects: ÑÐ»ÐµÐºÑÑÐ¾Ð»Ð¸Ð·
Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²Ð¾ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸Ñ
Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸Ð¹-ÑÑÑÐµÑ
ÑÐµÐ±ÐµÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÑ
ÐºÐ°Ð½Ð´Ð°Ð»Ð°ÐºÑÑÐºÐ¸Ð¹ Ð°Ð»Ð»ÑÐ¼Ð¸Ð½Ð¸ÐµÐ²ÑÐ¹ Ð·Ð°Ð²Ð¾Ð´
ÑÑÑÐ°Ð»
electrolysis
aluminum production
raw aluminum
cost
statistical data processing
kandalaksha aluminum plant
rusal

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð·Ð°ÐºÐ¾Ð½Ð¾Ð¼ÐµÑÐ½Ð¾ÑÑÐµÐ¹ ÑÐµÐ±ÐµÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÐ¸ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸Ñ-ÑÑÑÑÐ° ÐÐÐÐ° Ð² 21-Ð¾Ð¼ Ð²ÐµÐºÐµ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½ÑÑ Ð´Ð°Ð½Ð½ÑÑ ÐÐ°Ð½Ð´Ð°Ð»Ð°ÐºÑÑÐºÐ¾Ð³Ð¾ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸ÐµÐ²Ð¾Ð³Ð¾ Ð·Ð°Ð²Ð¾Ð´Ð° Ð·Ð° 2001-2022 Ð³Ð¾Ð´Ñ. Ð Ð°Ð±Ð¾ÑÐ° Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° Ð½Ð° Ð±Ð°Ð·Ðµ Â«ÐÐ°Ð½Ð´Ð°Ð»Ð°ÐºÑÑÐºÐ¸Ð¹ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸ÐµÐ²ÑÐ¹ Ð·Ð°Ð²Ð¾Ð´Â», Ð³Ð´Ðµ ÑÐ¾Ð±Ð¸ÑÐ°Ð»Ð¸ÑÑ Ð´Ð°Ð½Ð½ÑÐµ Ð¿Ð¾ ÑÐµÐ±ÐµÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÐ¸ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸Ñ-ÑÑÑÑÐ°. ÐÐ·ÑÑÐµÐ½Ð¾ ÐºÐ°Ðº Ð¸Ð·Ð¼ÐµÐ½Ð¸Ð»Ð°ÑÑ ÑÐµÐ±ÐµÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÑ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸Ñ Ð·Ð° ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÐµÐ¼ÑÐ¹ Ð¿ÐµÑÐ¸Ð¾Ð´, ÑÑÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð° ÑÑÑÑÐºÑÑÑÐ° ÑÐµÐ±ÐµÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÐ¸. ÐÐ·ÑÑÐµÐ½Ð¾ Ð²Ð»Ð¸ÑÐ½Ð¸Ðµ ÑÑÐ´Ð° Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½ÑÑ ÑÐ°ÐºÑÐ¾ÑÐ¾Ð² Ð½Ð° ÑÐµÐ±ÐµÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÑ: Ð²Ð»Ð¸ÑÐ½Ð¸Ðµ ÑÑÐ¾Ð²Ð½Ñ Ð¼ÐµÑÐ°Ð»Ð»Ð° Ð¸ ÑÑÐ¾Ð²Ð½Ñ ÑÐ»ÐµÐºÑÑÐ¾Ð»Ð¸ÑÐ°, ÑÐµÐ¼Ð¿ÐµÑÐ°ÑÑÑÑ, ÑÐ¸Ð»Ñ ÑÐ¾ÐºÐ°, Ð° ÑÐ°ÐºÐ¶Ðµ ÐºÑÐ¸Ð¾Ð»Ð¸ÑÐ¾Ð²Ð¾Ð³Ð¾ Ð¾ÑÐ½Ð¾ÑÐµÐ½Ð¸Ñ. ÐÐ°Ð½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð´Ð»Ñ ÑÐ½Ð¸Ð¶ÐµÐ½Ð¸Ñ ÑÐµÐ±ÐµÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÐ¸ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸Ñ-ÑÑÑÑÐ°. Ð ÐµÐ·ÑÐ»ÑÑÐ°ÑÑ ÐÐÐ  Ð¼Ð¾Ð³ÑÑ Ð±ÑÑÑ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ñ Ð² Ð¿ÑÐ°ÐºÑÐ¸ÐºÐµ ÐÐ°Ð½Ð´Ð°Ð»Ð°ÐºÑÑÐºÐ¾Ð³Ð¾ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸ÐµÐ²Ð¾Ð³Ð¾ Ð·Ð°Ð²Ð¾Ð´Ð°.
description: This work is devoted to the study of the regularities of the cost of raw KAZ aluminum in the 21st century based on the analysis of industrial data of the Kandalaksha aluminum plant for 2001-2022. The work was carried out on the basis of the Kandalaksha Aluminum Plant, where data on the cost of raw aluminum were collected. It has been studied how the cost price of aluminum has changed over the period under review, and the cost structure has been established. The influence of a number of production factors on the cost price has been studied: the influence of the metal level and the electrolyte level, temperature, current strength, as well as the cryolite ratio. Recommendations are given to reduce the cost of raw aluminum. The results of the WRC can be applied in the practice of the Kandalaksha aluminum plant.
Properties of the Hamiltonian Renormalisation and its application to quantum mechanics on the circle
Creators: name: Bahr, Benjamin
name: Liegener, Klaus
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Lattice (hep-lat)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We consider the Hamiltonian renormalisation group flow of discretised one-dimensional physical theories. In particular, we investigate the influence the choice of different embedding maps has on the RG flow and the resulting continuum limit, and show in which sense they are, and in which sense they are not equivalent as physical theories. We are furthermore elucidating the interplay of the RG flow and the algebras operators satisfy, both on the discrete and the continuum. Further, we propose preferred renormalisation prescriptions for operator algebras guaranteeing to arrive at preferred algebraic relations in the continuum, if suitable extension properties are assumed. Finally, we introduce a weaker form of distributional equivalence, and show how unitarily inequivalent continuum limits, which arise due to a choice of different embedding maps, can still be weakly equivalent in that sense.
description: 16 pages