cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
WEBINAR: Getting started with RNAseq: Transforming raw reads into biological insights
Creators: name: Deshpande, Nandan
name: Samaha, Georgina
Publisher: name: Zenodo
Year: 2023
Subjects: subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: Transcriptomics
subject: RNA-seq
subject: RNAseq
subject: Gene expression
subject: http://edamontology.org/topic_0091
subject: http://edamontology.org/topic_3308
subject: http://edamontology.org/topic_0203
subject: http://edamontology.org/topic_3170

description: This record includes training materials associated with the Australian BioCommons webinar ‘Getting started with RNAseq: Transforming raw reads into biological insights’. This webinar took place on 6 September 2023. Event description  RNA sequencing (RNAseq) is a powerful technique for investigating gene expression in biological samples. Processing and analysing RNAseq data involves multiple steps to align raw sequence reads to a reference genome, count the number of reads mapped to each gene, and perform statistical analyses to identify differentially expressed genes and functionally annotate them. RNAseq experiments have many different applications as we apply them to a variety of research questions and organisms. This diversity of applications can make it challenging to appreciate all the design considerations, processing requirements, and limitations of RNAseq experiments as they apply to you. In this webinar, you will gain an understanding of the key considerations for designing and performing your own successful experiments with bulk RNA. We’ll start at the lab bench with RNA extraction, quality control, and library preparation, then move to the sequencing machine where you will make essential decisions about sequencing platforms, optimal sequencing depth, and the importance of replicates. We’ll talk about bioinformatics workflows for RNAseq data processing and the computational requirements of transforming raw sequencing reads to analysis-ready count data. Finally, we’ll discuss how to apply differential expression and functional enrichment analyses to gain biological insights from differentially expressed genes. This webinar was developed by the Sydney Informatics Hub in collaboration with the Australian BioCommons. Training materials Materials are shared under a Creative Commons Attribution 4.0 International agreement unless otherwise specified and were current at the time of the event. Files and materials included in this record: Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc. Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file. Getting started with RNAseq: A PDF copy of the slides presented during the webinar.
 Materials shared elsewhere: A recording of this webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/tITR3WR_jWI
Local Unitary Equivalence of Multi-qubit Mixed quantum States
Creators: name: Li, Ming
name: Zhang, Tinggui
name: Fei, Shao-Ming
name: Li-Jost, Xianqing
name: Jing, Naihuan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present computable criterion for completely classifying multi-qubit quantum states under local unitary operations. The criterion can be used to detect whether two quantum states in multi-qubit systems are local unitary equivalent or not. Once obtaining the positive answer, we are further able to compute the corresponding unitary operators precisely. Since the scheme is based on the mean values of some quantum mechanical observables, it supplies an experimental way to judge the local equivalence of quantum states.
description: 6 pages
(:unas) unassigned
Creators: name: (:Unkn) Unknown
Publisher: name: Universita' degli Studi di Salerno
Year: 2024

description: Fabrizio Crisafulli parla in questa intervista del proprio approccio alla creazione teatrale affrontato sotto l’angolatura particolare dell’apporto del performer ai processi di scrittura scenica, della cooperazione tra performer e regista nell’operazione di tessitura drammaturgica, dello spettacolo come luogo di senso immanente e generatore di pensiero.
description: In this interview, Fabrizio Crisafulli talks about his approach to theatrical creation from the points of view of the performer's contribution to scenic composition, of the cooperation between performer and director in defining the work’s dramaturgical tissue, of the performance as a place of immanent meaning and producer of thought.
Geometrically controlled snapping transitions in shells with curved creases
Creators: name: Bende, Nakul P.
name: Evans, Arthur A.
name: Innes-Gold, Sarah
name: Marin, Luis A.
name: Cohen, Itai
name: Hayward, Ryan C.
name: Santangelo, Christian D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Curvature and mechanics are intimately connected for thin materials, and this coupling between geometry and physical properties is readily seen in folded structures from intestinal villi and pollen grains, to wrinkled membranes and programmable metamaterials. While the well-known rules and mechanisms behind folding a flat surface have been used to create deployable structures and shape transformable materials, folding of curved shells is still not fundamentally understood. Curved shells naturally deform by simultaneously bending and stretching, and while this coupling gives them great stability for engineering applications, it makes folding a surface of arbitrary curvature a non-trivial task. Here we discuss the geometry of folding a creased shell, and demonstrate theoretically the conditions under which it may fold continuously. When these conditions are violated we show, using experiments and simulations, that shells undergo rapid snapping motion to fold from one stable configuration to another. Although material asymmetry is a proven mechanism for creating this bifurcation of stability, for the case of a creased shell, the inherent geometry itself serves as a barrier to folding. We discuss here how two fundamental geometric concepts, creases and curvature, combine to allow rapid transitions from one stable state to another. Independent of material system and length scale, the design rule that we introduce here explains how to generate snapping transitions in arbitrary surfaces, thus facilitating the creation of programmable multi-stable materials with fast actuation capabilities.
Prevalence of Human African Trypanosomiasis in the Democratic Republic of the Congo
Creators: name: Kashamuka, Melchior M.
name: Mumba, Dieudonne
name: Tidwell, Richard
name: Meshnick, Steven R.
name: Kande, Victor
name: Bohorquez, Elaine
name: Messina, Jane
name: Tshefu, Antoinette K.
name: Muwonga, Jeremie
name: Taylor, Steven M.
name: Emch, Michael
name: Büscher, Philippe
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Human African Trypanosomiasis (HAT) is a major public health problem in the Democratic Republic of the Congo (DRC). Active and passive surveillance for HAT is conducted but may underestimate the true prevalence of the disease. We used ELISA to screen 7,769 leftover dried blood spots from a nationally representative population-based survey, the 2007 Demographic and Health Survey. 26 samples were positive by ELISA. Three of these were also positive by trypanolysis and/or PCR. From these data, we estimate that there were 18,592 people with HAT (95% confidence interval, 4,883–32,302) in the DRC in 2007, slightly more than twice as many as were reported.
Search for surviving companions in type Ia supernova remnants
Creators: name: Pan, Kuo-Chuan
name: Ricker, Paul M.
name: Taam, Ronald E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The nature of the progenitor systems of type~Ia supernovae is still unclear. One way to distinguish between the single-degenerate scenario and double-degenerate scenario for their progenitors is to search for the surviving companions. Using a technique that couples the results from multi-dimensional hydrodynamics simulations with calculations of the structure and evolution of main-sequence- and helium-rich surviving companions, the color and magnitude of main-sequence- and helium-rich surviving companions are predicted as functions of time. The surviving companion candidates in Galactic type~Ia supernova remnants and nearby extragalactic type~Ia supernova remnants are discussed. We find that the maximum detectable distance of main-sequence surviving companions (helium-rich surviving companions) is $0.6-4$~Mpc ($0.4-16$~Mpc), if the apparent magnitude limit is 27 in the absence of extinction, suggesting that the Large and Small Magellanic Clouds and the Andromeda Galaxy are excellent environments in which to search for surviving companions. However, only five Ia~SNRs have been searched for surviving companions, showing little support for the standard channels in the singe-degenerate scenario. To better understand the progenitors of type Ia supernovae, we encourage the search for surviving companions in other nearby type Ia supernova remnants.
description: 25 pages, 5 figures, and 2 tables. Accepted for publication in ApJ
Development and Characterization of a Reverse Genetic System for Studying Dengue Virus Serotype 3 Strain Variation and Neutralization
Creators: name: Yount, Boyd
name: Donaldson, Eric F.
name: de Silva, Aravinda M.
name: Baric, Ralph S.
name: Hacker, Kari E.
name: Huynh, Jeremy P.
name: Messer, William B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Dengue viruses (DENV) are enveloped single-stranded positive-sense RNA viruses transmitted by Aedes spp. mosquitoes. There are four genetically distinct serotypes designated DENV-1 through DENV-4, each further subdivided into distinct genotypes. The dengue scientific community has long contended that infection with one serotype confers lifelong protection against subsequent infection with the same serotype, irrespective of virus genotype. However this hypothesis is under increased scrutiny and the role of DENV genotypic variation in protection from repeated infection is less certain. As dengue vaccine trials move increasingly into field-testing, there is an urgent need to develop tools to better define the role of genotypic variation in DENV infection and immunity. To better understand genotypic variation in DENV-3 neutralization and protection, we designed and constructed a panel of isogenic, recombinant DENV-3 infectious clones, each expressing an envelope glycoprotein from a different DENV-3 genotype; Philippines 1982 (genotype I), Thailand 1995 (genotype II), Sri Lanka 1989 and Cuba 2002 (genotype III) and Puerto Rico 1977 (genotype IV). We used the panel to explore how natural envelope variation influences DENV-polyclonal serum interactions. When the recombinant viruses were tested in neutralization assays using immune sera from primary DENV infections, neutralization titers varied by as much as ∼19-fold, depending on the expressed envelope glycoprotein. The observed variability in neutralization titers suggests that relatively few residue changes in the E glycoprotein may have significant effects on DENV specific humoral immunity and influence antibody mediated protection or disease enhancement in the setting of both natural infection and vaccination. These genotypic differences are also likely to be important in temporal and spatial microevolution of DENV-3 in the background of heterotypic neutralization. The recombinant and synthetic tools described here are valuable for testing hypotheses on genetic determinants of DENV-3 immunopathogenesis.
Canadian Gallup Omnibus Poll May 1997
Creators: name: Gallup Canada, Inc.
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Vote in election(9); vote in last federal election(1); best prime minister for Canada(1); most important problem(1); party best able to handle problems(1); issue in federal election(10); party best able to handle specific problems(10); qualities of party leaders(7); defender of Canadian federalism(4); Donovan Bailey vs. Michael Johnson(1).
Canadian Gallup Omnibus Poll June 1997
Creators: name: Gallup Canada, Inc.
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Vote in election(3); vote in last federal election(1); political party support(4); Jean Chretien job performance(1); economy(2); worship in church, synagogue, or other place of worship(1); hunger problem in Canada(9).
Multifarious Assembly Mixtures: Systems Allowing Retrieval of Diverse Stored Structures
Creators: name: Murugan, Arvind
name: Zeravcic, Zorana
name: Brenner, Michael P.
name: Leibler, Stanislas
Publisher: name: arXiv
Year: 2014
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Self-assembly materials are traditionally designed so that molecular or meso-scale components form a single kind of large structure. Here, we propose a scheme to create "multifarious assembly mixtures", which self-assemble many different large structures from a set of shared components. We show that the number of multifarious structures stored in the solution of components increases rapidly with the number of different types of components. Yet, each stored structure can be retrieved by tuning only a few parameters, the number of which is only weakly dependent on the size of the assembled structure. Implications for artificial and biological self-assembly are discussed.
description: Paper + SI. Figures at the end
Drag force in strongly coupled, anisotropic plasma at finite chemical potential
Creators: name: Chakraborty, Somdeb
name: Haque, Najmul
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We employ methods of gauge/string duality to analyze the drag force on a heavy quark moving through a strongly coupled, anisotropic \mathcal{N}=4, SU(N) super Yang- Mills plasma in the presence of a finite U(1) chemical potential. We present numerical results valid for any value of the anisotropy parameter and the U(1) charge density and arbitrary direction of the quark velocity with respect to the direction of anisotropy. In the small anisotropy limit we are also able to furnish analytical results.
description: 24 pages, 16 eps figures
Neuronal control of locomotor handedness in Drosophila
Creators: name: Buchanan, Sean
name: Kain, Jamey
name: de Bivort, Benjamin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences

description: Handedness in humans - better performance using either the left or right hand - is personally familiar, moderately heritable, and regulated by many genes, including those involved in general body symmetry. But behavioral handedness, i.e. lateralization, is a multifaceted phenomenon. For example, people display clockwise or counter-clockwise biases in their walking behavior that is uncorrelated to their hand dominance, and lateralized behavioral biases have been shown in species as disparate as mice (paw usage), octopi (eye usage), and tortoises (side rolled on during righting). However, the mechanisms by which asymmetries are instilled in behavior are unknown, and a system for studying behavioral handedness in a genetically tractable model system is needed. Here we show that Drosophila melanogaster flies exhibit striking variability in their left-right choice behavior during locomotion. Very strongly biased "left-handed" and "right-handed" individuals are common in every line assayed. The handedness of an individual persists for its lifetime, but is not passed on to progeny, suggesting that mechanisms other than genetics determine individual handedness. We use the Drosophila transgenic toolkit to map a specific set of neurons within the central complex that regulates the strength of behavioral handedness within a line. These findings give insights into choice behaviors and laterality in a simple model organism, and demonstrate that individuals from isogenic populations reared under experimentally identical conditions nevertheless display idiosyncratic behaviors.
description: 14 pages, 13 figures
Pharmacology of DB844, an Orally Active aza Analogue of Pafuramidine, in a Monkey Model of Second Stage Human African Trypanosomiasis
Creators: name: Denton, Cathrine L.
name: Tidwell, Richard R.
name: Brun, Reto
name: Ching, Shelley
name: Paine, Mary F.
name: Kagira, John M.
name: Murilla, Grace A.
name: Wang, Michael Z.
name: Mdachi, Raymond E.
name: Boykin, David W.
name: Thuita, John K.
name: Hall, James E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Medicines against second stage HAT, where parasites have invaded the central nervous system (CNS). The pharmacology of a potential orally available lead compound, N-methoxy-6-{5-[4-(N-methoxyamidino) phenyl]-furan-2-yl}-nicotinamidine (DB844), was evaluated in a vervet monkey model of second stage HAT, following promising results in mice. DB844 was administered orally to vervet monkeys, beginning 28 days post infection (DPI) with Trypanosoma brucei rhodesiense KETRI 2537. DB844 was absorbed and converted to the active metabolite 6-[5-(4-phenylamidinophenyl)-furanyl-2-yl]-nicotinamide (DB820), exhibiting plasma Cmax values of 430 and 190 nM for DB844 and DB820, respectively, after the 14th dose at 6 mg/kg qd. A 100-fold reduction in blood trypanosome counts was observed within 24 h of the third dose and, at the end of treatment evaluation performed four days post the last drug dose, trypanosomes were not detected in the blood or cerebrospinal fluid of any monkey. However, some animals relapsed during the 300 days of post treatment monitoring, resulting in a cure rate of 3/8 (37.5%) and 3/7 (42.9%) for the 5 mg/kg×10 days and the 6 mg/kg×14 days dose regimens respectively. These DB844 efficacy data were an improvement compared with pentamidine and pafuramidine both of which were previously shown to be non-curative in this model of CNS stage HAT. These data show that synthesis of novel diamidines with improved activity against CNS-stage HAT was possible.
Composite Likelihood Estimation for Restricted Boltzmann machines
Creators: name: Yasuda, Muneki
name: Kataoka, Shun
name: Waizumi, Yuji
name: Tanaka, Kazuyuki
Publisher: name: arXiv
Year: 2014
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Learning the parameters of graphical models using the maximum likelihood estimation is generally hard which requires an approximation. Maximum composite likelihood estimations are statistical approximations of the maximum likelihood estimation which are higher-order generalizations of the maximum pseudo-likelihood estimation. In this paper, we propose a composite likelihood method and investigate its property. Furthermore, we apply our composite likelihood method to restricted Boltzmann machines.
Canadian Gallup Omnibus Poll September 1997
Creators: name: Gallup Canada, Inc.
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Vote in election(1); Jean Chretien job performance(1); direction of country(1); economy(2); personal financial situation(3); Canadian Constitution(1); Quebec vs. Canada(2); monarchy(2); landmines(1).
title: The ontologies of deep disagreements about children: Towards a non-representational methodology for social science
titleType: Other
Creators: name: McTaggart, James
Publisher: name: University of Dundee
Year: 2023

description: This thesis explores the ontologies involved for different sides in persisting disputes about children, specifically how different positions are based in different understandings of what children are. It opens with a survey of normative epistemological responses to disagreement, turning to an account of so-called deep disagreements that appear to be beyond resolution due to framework differences. Three ways to characterise these are explored in terms of epistemic injustice, conceptual metaphors and multiple ontologies and how these can overlap. The middle section develops and proposes social participatory realism as a methodology for studying deep disagreements, and for social science more generally, building on work in science and technology studies and a performative turn in mixed methods research. The methodology is illustrated in a critique of type-based attachment theory, and implications discussed for accounts of positionality and objectivity in research. The final section provides a meta-ethnographic synthesis of primary literature to create a map for how ontologies of childhood can differ. A Q methodology study uses this map to show that real differences in childhood ontologies do exist among different individuals. Finally, a content analysis of contributions to the debate over banning smacking in Scotland shows that different positions in this agreement align with sharply different views of what children are. Conclusions are drawn on the utility of a social participatory realist approach for research, and on the practice of ontological virtue as a means to deal with deep disagreements in practical contexts.
Spin negative differential resistance in edge doped zigzag graphene nanoribbons
Creators: name: Jiang, C.
name: Wang, X. F.
name: Zhai, M. X.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The nonlinear spin-dependent transport properties in zigzag graphene nanoribbons (ZGNRs) edge doped by an atom of group III and V elements are studied systematically using density functional theory combined with non-equilibrium Greens functions. The dopant type, acceptor or donor, and the geometrical symmetry, odd or even, are found critical in determining the spin polarization of the current and the current-voltage characteristics. For ZGNRs substitutionally doped on the lower-side edge, the down (up) spin current dominates in odd-(even-)width ZGNRs under a bias voltage around 1V. Remarkably, in even-width ZGNRs, doped by group III elements (B and Al), negative differential resistance (NDR) occurs only for down spins. The bias range of the spin NDR increases with the width of ZGNRs. The clear spin NDR is not observed in any odd-width ZGNRs nor in even-width ZGNRs doped by group V elements (N, and P). This peculiar spin NDR of edge doped ZGNRs suggests potential applications in spintronics.
Bushfire resistance of light gauge steel framed wall systems
Creators: name: Dart, Zoe
name: Watkins, Elise
name: Ariyanagam, Anthony
name: Mahendran, Mahen
Publisher: name: figshare
Year: 2023
Subjects: Fire safety engineering

description: The growing bush-to-urban interface, coupled with the increased severity of climate change impacts, has resulted in more frequent and widespread bushfire events. This increased severity and regularity of bushfire events has resulted in the destruction and costly rebuild of many residential homes across Australia, with over 3000 homes being destroyed in the recent 2019/2020 Black Summer Fires. With the significant and expensive damage caused by such events, incorporating bushfire resilience into residential design has become essential. Increasing the integrity of external wall configurations and thus improving the exterior building envelope is identified as a potential solution to minimise building losses during such events. This paper, therefore, presents the details of a bushfire resistance experiment and associated research conducted for multiple external light gauge steel framed (LSF) wall configurations against various Bushfire Attack Levels (BAL) given in bushfire standards by using relevant radiant heat fire curves. This study aims to improve the knowledge base of the bushfire resistance of external LSF wall configurations, aid in the design of safe bushfire-prone buildings, improve community resilience, limit material wastage, and reduce the economic burden of bushfire attacks.
Canadian Omnibus Poll: December 1997
Creators: name: Gallup Canada, Inc.
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Vote in election(2); Jean Chretien job performance(1); economy(3); unemployment(1); business conditions(2); satisfaction with services in your community(20); good time to buy(3); personal financial situation(3); standard of living(2); charitable contributions(3).
Akad wakalah pada inklusi keuangan syariah: Studi pustaka (library research) dan Bibliometrik Vosviewer
Creators: name: Panatagama, Ahmad Ramapanji
name: Budianto, Eka Wahyu Hestya
name: Dewi, Nindi Dwi Tetria
Publisher: name: Zenodo
Year: 2023
Subjects: Akad Wakalah
Inklusi Keuangan Syariah
Studi Pustaka
Library Research
Bibliometrik
VOSviewer

description: Penelitian ini bertujuan untuk memetakan topik penelitian seputar akad Wakalah pada Inklusi Keuangan Syariah dengan pendekatan kualitatif, yang bersifat studi pustaka (library research). Teknik pengumpulan data dengan: pertama, membuka sofware Perish/Harzing, lalu mencari jurnal berdasarkan kategori title words berkata kunci "Wakalah" dalam kurun waktu seluruh tahun. Kedua, mengumpulkan data judul jurnal dalam Microsoft Excel, dan mengidentifikasi judul jurnal yang ganda. Ketiga, mengunduh file berformat RIS (Research Information Systems) dan PDF (Portable Document Format) dari seluruh jurnal yang telah dikumpulkan datanya. Keempat, memasukkan file data RIS ke dalam software Mendeley Dekstop. Teknik analisis data dengan memetakan topik penelitian seputar akad Wakalah berdasarkan jurnal-jurnal yang telah dikumpulkan. Hasil penelitian menunjukkan bahwa terdapat 5 pemetaan topik penelitian seputar akad Wakalah, yaitu: (1) Penerapan akad Wakalah; (2) Pengaruh akad Wakalah; (3) Pandangan hukum Islam, hukum positif, dan perundang-undangan seputar akad Wakalah; (4) Upaya pengembangan akad Wakalah; dan (5) Isu-isu lainnya yang berkaitan dengan akad Wakalah. Implikasi dan kontribusi penelitian ini adalah pemetaan topik-topik penelitian seputar akad Wakalah, baik yang sering ataupun jarang diteliti oleh peneliti, sehingga peneliti lainnya dapat mengetahui kekosongan penelitian dalam topik ini.
Correlation between Dengue-Specific Neutralizing Antibodies and Serum Avidity in Primary and Secondary Dengue Virus 3 Natural Infections in Humans
Creators: name: Puschnik, Andreas
name: Lau, Louis
name: Harris, Eva
name: Balmaseda, Angel
name: Cromwell, Elizabeth A.
name: Zompi, Simona
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Although heterotypic secondary infection with dengue virus (DENV) is associated with severe disease, the majority of secondary infections are mild or asymptomatic. The mechanisms of antibody-mediated protection are poorly understood. In 2010, 108 DENV3-positive cases were enrolled in a pediatric hospital-based study in Managua, Nicaragua, with 61 primary and 47 secondary infections. We analyzed DENV-specific neutralization titers (NT50), IgM and IgG avidity, and antibody titer in serum samples collected during acute and convalescent phases and 3, 6, and 18 months post-infection. NT50 titers peaked at convalescence and decreased thereafter. IgG avidity to DENV3 significantly increased between convalescent and 3-month time-points in primary DENV infections and between the acute and convalescent phase in secondary DENV infections. While avidity to DENV2, a likely previous infecting serotype, was initially higher than avidity to DENV3 in secondary DENV infections, the opposite relation was observed 3–18 months post-infection. We found significant correlations between IgM avidity and NT50 in acute primary cases and between IgG avidity and NT50 in secondary DENV infections. In summary, our findings indicate that IgM antibodies likely play a role in early control of DENV infections. IgG serum avidity to DENV, analyzed for the first time in longitudinal samples, switches from targeting mainly cross-reactive serotype(s) to the current infecting serotype over time. Finally, serum avidity correlates with neutralization capacity.
Gallup Canada Poll #199801: Election/News Sources/Immigrants
Creators: name: Gallup Canada, Inc.
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Political party (2); Jean Chretien job performance (1); most important problem (2); news sources (1); relationship with spouse/partner (1); Valentine's Day (1); language of Landed Immigrants (2); religious preference (1).
AirDOS: Dynamic SLAM benefits from Articulated Objects
Creators: name: Qiu, Yuheng
name: Wang, Chen
name: Wang, Wenshan
name: Henein, Mina
name: Scherer, Sebastian
Publisher: name: arXiv
Year: 2021
Subjects: subject: Robotics (cs.RO)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Dynamic Object-aware SLAM (DOS) exploits object-level information to enable robust motion estimation in dynamic environments. Existing methods mainly focus on identifying and excluding dynamic objects from the optimization. In this paper, we show that feature-based visual SLAM systems can also benefit from the presence of dynamic articulated objects by taking advantage of two observations: (1) The 3D structure of each rigid part of articulated object remains consistent over time; (2) The points on the same rigid part follow the same motion. In particular, we present AirDOS, a dynamic object-aware system that introduces rigidity and motion constraints to model articulated objects. By jointly optimizing the camera pose, object motion, and the object 3D structure, we can rectify the camera pose estimation, preventing tracking loss, and generate 4D spatio-temporal maps for both dynamic objects and static scenes. Experiments show that our algorithm improves the robustness of visual SLAM algorithms in challenging crowded urban environments. To the best of our knowledge, AirDOS is the first dynamic object-aware SLAM system demonstrating that camera pose estimation can be improved by incorporating dynamic articulated objects.
Compressed Relaying for Two-Way Relay Networks with Correlated Sources
Creators: name: Huo, Qiang
name: Yang, Kun
name: Song, Lingyang
name: Li, Yonghui
name: Jiao, Bingli
Publisher: name: arXiv
Year: 2014
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: In this letter, a compressed relaying scheme via Huffman and physical-layer network coding (HPNC) is proposed for two-way relay networks with correlated sources (TWRN-CS). In the HPNC scheme, both sources first transmit the correlated raw source messages to the relay simultaneously. The relay performs physical-layer network coding (PNC) on the received symbols, compresses the PNC-coded symbols using Huffman coding, and broadcasts the compressed symbols to both source nodes. Then, each source decodes the other source's messages by using its own messages as side information. Compression rate and block error rate (BLER) of the proposed scheme are analyzed. Simulation results demonstrate that the HPNC scheme can effectively improve the network throughput, and meanwhile, achieve the superior BLER performance compared with the conventional non-compressed relaying scheme in TWRN-CS.
description: 11 pages, 4 figures. appears in IEEE Wireless Communications Letters, 2014
Onset of universality in the dynamical mixing of a pure state
Creators: name: Carrera-Núñez, M.
name: Martínez-Argüello, A. M.
name: Torres, J. M.
name: Torres-Herrera, E. J.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the time dynamics of random density matrices generated by evolving the same pure state using a Gaussian orthogonal ensemble (GOE) of Hamiltonians. We show that the spectral statistics of the resulting mixed state is well described by random matrix theory (RMT) and undergoes a crossover from the GOE to the Gaussian unitary ensemble (GUE) for short and large times respectively. Using a semi-analytical treatment relying on a power series of the density matrix as a function of time, we find that the crossover occurs in a characteristic time that scales as the inverse of the Hilbert space dimension. The RMT results are contrasted with a paradigmatic model of many-body localization in the chaotic regime, where the GUE statistics is reached at large times, while for short times the statistics strongly depends on the peculiarity of the considered subspace.
description: 10 pages, 3 figures
High-energy emissions from the gamma-ray binary LS 5039
Creators: name: Takata, J.
name: Leung, Gene C. K.
name: Tam, P. H. T.
name: Kong, A. K. H.
name: Hui, C. Y.
name: Cheng, K. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We study mechanisms of multi-wavelength emissions (X-ray, GeV and TeV gamma-rays) from the gamma-ray binary LS~5039. This paper is composed of two parts. In the first part, we report on results of observational analysis using four year data of \fermi\ Large Area Telescope. Due to the improvement of instrumental response function and increase of the statistics, the observational uncertainties of the spectrum in $\sim$100-300 MeV bands and $>10$GeV bands are significantly improved. The present data analysis suggests that the 0.1-100GeV emissions from LS~5039 contain three different components; (i) the first component contributes to $
description: 51 pages, 15 figures, accepted for publication in ApJ
GSIP: Green Semantic Segmentation of Large-Scale Indoor Point Clouds
Creators: name: Zhang, Min
name: Kadam, Pranav
name: Liu, Shan
name: Kuo, C. -C. Jay
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: An efficient solution to semantic segmentation of large-scale indoor scene point clouds is proposed in this work. It is named GSIP (Green Segmentation of Indoor Point clouds) and its performance is evaluated on a representative large-scale benchmark -- the Stanford 3D Indoor Segmentation (S3DIS) dataset. GSIP has two novel components: 1) a room-style data pre-processing method that selects a proper subset of points for further processing, and 2) a new feature extractor which is extended from PointHop. For the former, sampled points of each room form an input unit. For the latter, the weaknesses of PointHop's feature extraction when extending it to large-scale point clouds are identified and fixed with a simpler processing pipeline. As compared with PointNet, which is a pioneering deep-learning-based solution, GSIP is green since it has significantly lower computational complexity and a much smaller model size. Furthermore, experiments show that GSIP outperforms PointNet in segmentation performance for the S3DIS dataset.
description: 10 pages, 3 figures
Estimates of Dengue Force of Infection in Children in Colombo, Sri Lanka
Creators: name: Margolis, Harold S.
name: de Silva, Aravinda M.
name: De Silva, Aruna Dharshan
name: Amarasinge, Ananda
name: Tam, Clarence C.
name: Tissera, Hasitha
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Dengue is the most important vector-borne viral disease worldwide and a major cause of childhood fever burden in Sri Lanka, which has experienced a number of large epidemics in the past decade. Despite this, data on the burden and transmission of dengue virus in the Indian Subcontinent are lacking. As part of a longitudinal fever surveillance study, we conducted a dengue seroprevalence survey among children aged <12 years in Colombo, Sri Lanka. We used a catalytic model to estimate the risk of primary infection among seronegative children. Over 50% of children had IgG antibodies to dengue virus and seroprevalence increased with age. The risk of primary infection was 14.1% per year (95% CI: 12.7%–15.6%), indicating that among initially seronegative children, approximately 1 in 7 experience their first infection within 12 months. There was weak evidence to suggest that the force of primary infection could be lower for children aged 6 years and above. We estimate that there are approximately 30 primary dengue infections among children <12 years in the community for every case notified to national surveillance, although this ratio is closer to 100∶1 among infants. Dengue represents a considerable infection burden among children in urban Sri Lanka, with levels of transmission comparable to those in the more established epidemics of Southeast Asia.
Learning non-monotone optimal individualized treatment regimes
Creators: name: Ghosh, Trinetri
name: Ma, Yanyuan
name: Zhu, Wensheng
name: Wang, Yuanjia
Publisher: name: arXiv
Year: 2021
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: We propose a new modeling and estimation approach to select the optimal treatment regime from different options through constructing a robust estimating equation. The method is protected against misspecification of the propensity score model, the outcome regression model for the non-treated group, or the potential non-monotonic treatment difference model. Our method also allows residual errors to depend on covariates. A single index structure is incorporated to facilitate the nonparametric estimation of the treatment difference. We then identify the optimal treatment through maximizing the value function. Theoretical properties of the treatment assignment strategy are established. We illustrate the performance and effectiveness of our proposed estimators through extensive simulation studies and a real dataset on the effect of maternal smoking on baby birth weight.
description: 32 pages, 7 figures, 8 tables
Spin-dependent ballistic transport properties and electronic structures of pristine and edge-doped zigzag silicene nanoribbons: large magnetoresistance
Creators: name: Chen, A. B.
name: Wang, X. F.
name: Vasilopoulos, P.
name: Zhai, M. X.
name: Liu, Y. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The electronic structure and conductance of substitutionally edge-doped zigzag silicene nanoribbons (ZSiNRs) are investigated using the nonequilibrium Green's function method combined with the density functional theory. Two-probe systems of ZSiNRs in both ferromagnetic and antiferromagnetic states are considered. Doping effects of elements from groups III and V, in a parallel or antiparallel magnetic configuration of the two electrodes, are discussed. Switching on and off the external magnetic field, we may convert the metallic ferromagnetic ZSiNRs into insulating antiferromagnetic ZSiNRs. In the ferromagnetic state, even- or odd-width ZSiNRs exhibit a drastically different magnetoresistance. In an odd-width edge-doped ZSiNR a large magnetoresistance occurs compared to that in a pristine ZSiNR. The situation is reversed in even-width ZSiNRs. These phenomena result from the drastic change of the conductance in the antiparallel configuration.
Topological states in a dimerized system with staggered magnetic fluxes
Creators: name: He, Ai-Lei
name: Luo, Wei-Wei
name: Zhou, Yuan
name: Wang, Yi-Fei
name: Yao, Hong
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The bulk-boundary correspondence is a generic feature of topological states of matter, reflecting the intrinsic relation between topological bulk and boundary states. For example, robust edge states propagate along the edges and corner states gather at corners in the two-dimensional first-order and second-order topological insulators, respectively. Here, we report two kinds of topological states hosting anomalous bulk-boundary correspondence in the extended two-dimensional dimerized lattice with staggered flux threading. At $\frac{1}{2}$-filling, we observe isolated corner states with no fractional charge as well as metallic near-edge states in the $\mathcal{C}=2$ Chern insulator states. At $\frac{1}{4}$-filling, we find a $\mathcal{C}=0$ topologically nontrivial state, where the robust edge states are well localized along edges but bypass corners. These robust topological insulating states significantly differ from both conventional Chern insulators and usual high-order topological insulators.
description: 5.5+6.5 pages, 5+9 figures
Gallup Canada Poll #199803: Election/Charest
Creators: name: Gallup Canada, Inc.
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Political parties (2); Jean Chretien job performance (1); direction of country (1); new budget (3); Jean Charest (4); honesty and ethical standards (1); accused young offenders (2); marijuana (2); religious preference (1).
Formation of a stable surface oxide in MnBi$_2$Te$_4$ thin films
Creators: name: Akhgar, Golrokh
name: Li, Qile
name: Di Bernardo, Iolanda
name: Trang, Chi Xuan
name: Liu, Chang
name: Karel, Julie
name: Tadich, Anton
name: Fuhrer, Michael S.
name: Edmonds, Mark T.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Understanding the air-stability of MnBi$_2$Te$_4$ thin films is crucial for the development and long-term operation of electronic devices based around magnetic topological insulators. In the present work, we study MnBi$_2$Te$_4$ thin films upon exposure to atmosphere using a combination of synchrotron-based photoelectron spectroscopy, room temperature electrical transport and atomic force microscopy to determine the oxidation process. After 2 days air exposure a 2 nm thick oxide passivates the surface, corresponding to oxidation of only the top two surface layers, with the underlying layers preserved. This protective oxide layer results in samples that still exhibit metallic conduction even after several days air exposure. Furthermore, the work function decreases from 4.4 eV for pristine MnBi$_2$Te$_4$ to 4.0 eV after the formation of the oxide, along with only a small shift in the core levels indicating minimal doping as a result of air exposure. With the oxide confined to the top surface layers, and the underlying layers preserved, it may be possible to explore new avenues in how to handle, prepare and passivate future MnBi$_2$Te$_4$ devices.
Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypanosomiasis
Creators: name: Tidwell, Richard R.
name: Liu, Qiang
name: Mdachi, Raymond E.
name: Chen, Yao
name: Mutuku, James N.
name: Wolf, Kristina K.
name: Thuita, John K.
name: Boykin, David W.
name: Murilla, Grace A.
name: Hall, James Edwin
name: Wang, Michael Zhuo
name: Bridges, Arlene S.
name: Ismail, Mohamed A.
name: Ching, Shelley
name: Paine, Mary F.
name: Brun, Reto
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness). A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus reducing healthcare costs of HAT. The development of oral medications is a key objective of the Consortium for Parasitic Drug Development (CPDD). In this study, we investigated the safety, pharmacokinetics, and efficacy of a new orally administered CPDD diamidine prodrug, 2,5-bis[5-(N-methoxyamidino)-2-pyridyl]furan (DB868; CPD-007-10), in the vervet monkey model of first stage HAT. DB868 was well tolerated at a dose up to 30 mg/kg/day for 10 days, a cumulative dose of 300 mg/kg. Mean plasma levels of biomarkers indicative of liver injury (alanine aminotransferase, aspartate aminotransferase) were not significantly altered by drug administration. In addition, no kidney-mediated alterations in creatinine and urea concentrations were detected. Pharmacokinetic analysis of plasma confirmed that DB868 was orally available and was converted to the active compound DB829 in both uninfected and infected monkeys. Treatment of infected monkeys with DB868 began 7 days post-infection. In the infected monkeys, DB829 attained a median Cmax (dosing regimen) that was 12-fold (3 mg/kg/day for 7 days), 15-fold (10 mg/kg/day for 7 days), and 31-fold (20 mg/kg/day for 5 days) greater than the IC50 (14 nmol/L) against T. b. rhodesiense STIB900. DB868 cured all infected monkeys, even at the lowest dose tested. In conclusion, oral DB868 cured monkeys with first stage HAT at a cumulative dose 14-fold lower than the maximum tolerated dose and should be considered a lead preclinical candidate in efforts to develop a safe, short course (5–7 days), oral regimen for first stage HAT.
Divergence error based $p$-adaptive discontinuous Galerkin solution of time-domain Maxwell's equations
Creators: name: Tiwari, Apurva
name: Chatterjee, Avijit
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Numerical Analysis (math.NA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: A $p$-adaptive discontinuous Galerkin time-domain method is developed to obtain high-order solutions to electromagnetic scattering problems. A novel feature of the proposed method is the use of divergence error to drive the $p$-adaptive method. The nature of divergence error is explored and that it is a direct consequence of the act of discretization is established. Its relation with relative truncation error is formed which enables the use of divergence error as an inexpensive proxy to truncation error. Divergence error is used as an indicator to dynamically identify and assign spatial operators of varying accuracy to substantial regions in the computational domain. This results in a reduced computational cost than a comparable discontinuous Galerkin time-domain solution using uniform degree piecewise polynomial bases throughout.
description: 28 pages, 22 figures