cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Evaluation of tumor-infiltrating lymphocytes and mammographic density as predictors of response to neoadjuvant systemic therapy in breast cancer
Creators: name: Landén, Amalia H.
name: Chin, Kian
name: Kovács, Anikó
name: Holmberg, Erik
name: Molnar, Eva
name: Tullberg, Axel Stenmark
name: Wärnberg, Fredrik
name: Karlsson, Per
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Response rates vary among breast cancer patients treated with neoadjuvant systemic therapy (NAST). Thus, there is a need for reliable treatment predictors. Evidence suggests tumor-infiltrating lymphocytes (TILs) predict NAST response. Still, TILs are seldom used clinically as a treatment determinant. Mammographic density (MD) is another potential marker for NAST benefit and its relationship with TILs is unknown. Our aims were to investigate TILs and MD as predictors of NAST response and to study the unexplored relationship between TILs and MD. We studied 315 invasive breast carcinomas treated with NAST between 2013 and 2020. Clinicopathological data were retrieved from medical records. The endpoint was defined as pathological complete response (pCR) in the breast. TILs were evaluated in pre-treatment core biopsies and categorized as high (≥10%) or low (<10%). MD was scored (a–d) according to the breast imaging reporting and data system (BI-RADS) fifth edition. Binary logistic regression and Spearman’s test of correlation were performed using SPSS. Out of 315 carcinomas, 136 achieved pCR. 94 carcinomas had high TILs and 215 had low TILs. Six carcinomas had no available TIL data. The number of carcinomas in each BI-RADS category were 37, 122, 112, and 44 for a, b, c, and d, respectively. High TILs were independently associated with pCR (OR: 2.95; 95% CI: 1.59–5.46) compared to low TILs. In the univariable analysis, MD (BI-RADS d vs. a) showed a tendency of higher likelihood for pCR (OR: 2.43; 95% CI: 0.99–5.98). However, the association was non-significant, which is consistent with the result of the multivariable analysis (OR: 2.51; 95% CI: 0.78–8.04). We found no correlation between TILs and MD (0.02; p = .80). TILs significantly predicted NAST response. We could not define MD as a significant predictor of NAST response. These findings should be further replicated.
Additional file 1 of Exploring the relationship between intron retention and chromatin accessibility in plants
Creators: name: Ullah, Fahad
name: Hamilton, Michael
name: Anireddy Reddy
name: Ben-Hur, Asa
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: SupplementaryFile_1.docx. Additional figures and tables are provided in this file. (DOCX 2507 kb)
Additional file 1 of Myocardial transcriptomic analysis of diabetic patients with aortic stenosis: key role for mitochondrial calcium signaling
Creators: name: Cherpaz, Maelle
name: Meugnier, Emmanuelle
name: Seillier, Gaultier
name: Pozzi, Matteo
name: Pierrard, Romain
name: Leboube, Simon
name: Farhat, Fadi
name: Vola, Marco
name: Obadia, Jean-François
name: Amaz, Camille
name: Chalabreysse, Lara
name: May, Chloe
name: Chanon, Stephanie
name: Brun, Camille
name: Givre, Lucas
name: Bidaux, Gabriel
name: Mewton, Nathan
name: Derumeaux, Genevieve
name: Bergerot, Cyrille
name: Paillard, Melanie
name: Thibault, Helene
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary material
Relaxation of Radiation-Driven Two-Level Systems Interacting with a Bose-Einstein Condensate Bath
Creators: name: Kovalev, Vadim M.
name: Tse, Wang-Kong
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We develop a microscopic theory for the relaxation dynamics of an optically pumped two-level system (TLS) coupled to a bath of weakly interacting Bose gas. Using Keldysh formalism and diagrammatic perturbation theory, expressions for the relaxation times of the TLS Rabi oscillations are derived when the boson bath is in the normal state and the Bose-Einstein condensate (BEC) state. We apply our general theory to consider an irradiated quantum dot coupled with a boson bath consisting of a two-dimensional dipolar exciton gas. When the bath is in the BEC regime, relaxation of the Rabi oscillations is due to both condensate and non-condensate fractions of the bath bosons for weak TLS-light coupling and dominantly due to the non-condensate fraction for strong TLS-light coupling. Our theory also shows that a phase transition of the bath from the normal to the BEC state strongly influences the relaxation rate of the TLS Rabi oscillations. The TLS relaxation rate is approximately independent of the pump field frequency and monotonically dependent on the field strength when the bath is in the low-temperature regime of the normal phase. Phase transition of the dipolar exciton gas leads to a non-monotonic dependence of the TLS relaxation rate on both the pump field frequency and field strength, providing a characteristic signature for the detection of BEC phase transition of the coupled dipolar exciton gas.
description: 13 pages, 7 figures
Persistierende frühkindliche Reflexe in der Logopädie Vergleich der realen Praxis mit den Vorstellungen von Expertinnen
Creators: name: Fedier, Sina
name: Frisina, Emanuela
Publisher: name: Zenodo
Year: 2018
Subjects: Logopädie
Bachelorarbeit

description: Diese Bachelorarbeit beschäftigt sich mit den persistierenden frühkindlichen Reflexen1 in der Logopädie. Als Einstieg werden die für die Therapie relevanten Reflexe theoretisch aufgear-beitet. Anhand von zwei Interviews mit Logopädinnen, die die erwähnten Reflexe in ihre lo-gopädische Arbeit mit einbeziehen und einer Onlineumfrage unter Deutschschweizer Logo-pädinnen und Logopäden, untersucht sie die Frage, wie sich Pro und Contra im Bewusst-sein, der Denkweise und in der Überzeugung über die persistierenden frühkindlichen Reflexe in der logopädischen Therapie zeigt. Die Tendenzen der Aussagen der Expertinnen und die Auswertungen der Onlineumfrage haben ergeben, dass die persistierenden frühkindlichen Reflexe ein grosser Gewinn für den Therapiealltag sein können. Die behandelte Thematik ist zwar weit herum bekannt, aber noch nicht in der deutschschweizerischen logopädischen Kultur verankert.
WW management strategies and water & land management strategies in agriculture
Creators: name: Varela-Ortega, Consuelo
name: Boubakri, Najib
name: Blanco, Irene
name: Sangro, Sebastián
name: Scardigno, Alessandra
name: Lamaddalena, Nicola
name: Oertlé, Emmanuel
name: Müller, Sandra
name: Dietziker, Andrin
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2020
Subjects: ING-IND/25 Impianti chimici

description: The general objective of the MADFORWATER project is to develop integrated technological and management solutions to boost wastewater treatment and treated wastewater efficient reuse for irrigation in selected hydrological basins in Egypt, Morocco and Tunisia. In particular, Work Package (WP) 5 ‘’ Strategies and economic instruments for basin-scale water resources management’’ aims to develop strategies for wastewater management, water reuse and water & land management in agriculture, tailored to the three studied basins. This WP will make use of two decision support tools (DSTs) to support the development of strategies and economic instruments for wastewater management and water & land management in agriculture. In this deliverable 5.2, the wastewater management strategies and the strategies for water management in agriculture are developed separately. The proposed two types of strategies will then be combined into basin-scale integrated water & land management strategies in the upcoming deliverable 6.1.
Metal-insulator-metal transition in NdNiO3 films capped by CoFe2O4
Creators: name: Saleem, M. S.
name: Song, C.
name: Peng, J. J.
name: Cui, B.
name: Li, F.
name: Gu, Y. D.
name: Pan, F.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Metal-insulator transition features as a transformation, from a highly charge conductive state to another state where charge conductivity is greatly suppressed when decreasing the temperature. Here we demonstrate two consecutive transitions in NdNiO3 films with CoFe2O4 capping, in which the metal-insulator transition occurs at 85 K, followed by an unprecedented insulator-metal transition below 40 K. The emerging insulator-metal transition associated with a weak antiferromagnetic behavior is observed in 20 unit cell-thick NdNiO3 with more than 5 unit cell CoFe2O4 capping. Differently, the NdNiO3 films with thinner CoFe2O4 capping only exhibit metal-insulator transition at 85 K, accompanied by a strong antiferromagnetic state below 40 K. Charge transfer from Co to Ni, instead of from Fe to Ni, formulates the ferromagnetic interaction between Ni-Ni and Ni-Co atoms, thus suppressing the antiferromagnetic feature and producing metallic conductive behavior. Furthermore, a phase diagram for the metal-insulator-metal transition in this system is drawn.
description: 14 pages, 5 figures, to appear in Appl. Phys. Lett
Additional file 1: Figure S1. of Genomic abundance and transcriptional activity of diverse gypsy and copia long terminal repeat retrotransposons in three wild sunflower species
Creators: name: Qiu, Fan
name: Ungerer, Mark
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Pearsonâ s correlation between density of reads and nuclear genome size for gypsy and copia elements. Figure S2. Phylogenetic relationship among different sublineages of (A) gypsy and (B) copia based on amino acid sequences of the reverse transcriptase domain (gypsy, 173 a.a.; copia, 250 a.a.) using maximum likelihood. Bootstrap scores are presented for internal branches with >50% support. Table S1. Summary statistics of DNA-seq and RNA-seq data. (PDF 488Â kb)
STAT3-EphA7 axis contributes to the progression of esophageal squamous cell carcinoma
Creators: name: Wang, Li
name: Zhao, Qiao-Feng
name: Yang, Bing-Bing
name: Liang, Hui-Jie
name: Zhang, Xian-E
name: Zhang, Xiao-Yan
name: Yang, Wan-Jing
name: Guo, Zhi-Yu
name: Xu, Xin
name: Tian, Fang
name: Wu, Qing-Hua
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Our previous study has revealed that EphA7 was upregulated in patient-derived esophageal squamous cell carcinoma (ESCC) xenografts with hyper-activated STAT3, but its mechanism was still unclear. To assess the association between EphA7 and STAT3, western blotting, immunofluorescence, ChIP assay, and qRT-PCR were conducted. Truncated mutation and luciferase assay were performed to examine the promoter activity of EphA7. CCK-8 assay and colony formation were performed to assess the proliferation of ESCC. Cell-derived xenograft models were established to evaluate the effects of EphA7 on ESCC tumor growth. RNA-seq analyses were used to assess the effects of EphA7 on related signals. In this study, EphA7 was found upregulated in ESCC cell lines with high STAT3 activation, and immunofluorescence also showed that EphA7 was co-localized with phospho-STAT3 in ESCC cells. Interestingly, suppressing STAT3 activation by the STAT3 inhibitor Stattic markedly inhibited the protein expression of EphA7 in ESCC cells, in contrast, activation of STAT3 by IL-6 obviously upregulated the protein expression of EphA7. Moreover, the transcription of EphA7 was also mediated by the activation of STAT3 in ESCC cells, and the −2000∼−1500 region was identified as the key promoter of EphA7. Our results also indicated that EphA7 enhanced the cell proliferation of ESCC, and silence of EphA7 significantly suppressed ESCC tumor growth. Moreover, EphA7 silence markedly abolished STAT3 activation-derived cell proliferation of ESCC. Additionally, RNA-seq analyses indicated that several tumor-related signaling pathways were significantly changed after EphA7 downregulation in ESCC cells. Our results showed that the transcriptional expression of EphA7 was increased by activated STAT3, and the STAT3 signaling may act through EphA7 to promote the development of ESCC.
CurviTrack: Curvilinear Trajectory Tracking for High-speed Chase of a USV
Creators: name: Gupta, Parakh M.
name: Procházka, Ondřej
name: Nascimento, Tiago
name: Saska, Martin
Publisher: name: arXiv
Year: 2025
Subjects: subject: Robotics (cs.RO)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Heterogeneous robot teams used in marine environments incur time-and-energy penalties when the marine vehicle has to halt the mission to allow the autonomous aerial vehicle to land for recharging. In this paper, we present a solution for this problem using a novel drag-aware model formulation which is coupled with MPC, and therefore, enables tracking and landing during high-speed curvilinear trajectories of an USV without any communication. Compared to the state-of-the-art, our approach yields 40% decrease in prediction errors, and provides a 3-fold increase in certainty of predictions. Consequently, this leads to a 30% improvement in tracking performance and 40% higher success in landing on a moving USV even during aggressive turns that are unfeasible for conventional marine missions. We test our approach in two different real-world scenarios with marine vessels of two different sizes and further solidify our results through statistical analysis in simulation to demonstrate the robustness of our method.
Familial features affecting the melanoma risk in CDKN2A-negative melanoma families: a study based on the Swedish Cancer Registry
Creators: name: Helgadottir, Hildur
name: Schultz, Karina
name: Lapins, Jan
name: Höiom, Veronica
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Virology

description: Familial features affecting the melanoma risk in CDKN2A-negative melanoma families: a study based on the Swedish Cancer Registry
Updating the Born rule
Creators: name: Shrapnel, Sally
name: Costa, Fabio
name: Milburn, Gerard
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Despite the tremendous empirical success of quantum theory there is still widespread disagreement about what it can tell us about the nature of the world. A central question is whether the theory is about our knowledge of reality, or a direct statement about reality itself. Regardless of their stance on this question, current interpretations of quantum theory regard the Born rule as fundamental and add an independent state-update (or "collapse") rule to describe how quantum states change upon measurement. In this paper we present an alternative perspective and derive a probability rule that subsumes both the Born rule and the collapse rule. We show that this more fundamental probability rule can provide a rigorous foundation for informational, or "knowledge-based", interpretations of quantum theory.
description: 6+2 pages; 3 figures
Zum Verhältnis von Neuropsychologie und Logopädie im Kontext Rehabilitation bei Aphasie Literaturrecherche und Einblicke in "good practice"
Creators: name: Imboden, Désirée
name: Erni, Linda
Publisher: name: Zenodo
Year: 2018
Subjects: Logopädie
Aphasie
Therapie
Bachelorarbeit

description: In der vorliegenden Arbeit wird aufgezeigt, welche Basisfunktionen als Einflussfaktoren in der Rehabilitation von Aphasie in welcher Weise relevant sind und ob es zwischen Logopädie und Neuropsychologie disziplinäre Überschneidungen im Kontext Rehabilitation bei Aphasie gibt. Dabei wird auf die Thematik der Interprofessionalität eingegangen. Zur theoretischen Beantwortung beider Fragen wurde eine Literaturrecherche gemacht. Um die dadurch gewonnenen Antworten auf die zweite Frage mit einem Praxisbeispiel zu ergänzen, wurde zusätzlich ein Experteninterview durchgeführt. Die Fakten aus der Literatur und die Antworten des Experteninterviews zeigten bis auf wenige Unterschiede eine grosse Übereinstimmung. Dies lässt vermuten, dass die Thematiken Interdisziplinarität und Interprofessionalität in der Literatur klar dargestellt sind und sich interprofessionelle Arbeitsweisen, als Folge davon, in der Praxis etabliert haben. Jedoch wurde herausgearbeitet, dass Interdisziplinarität und Interprofessionalität in der Literatur zwar oft erwähnt werden, jedoch meist zu unspezifisch, um daraus eine konkrete Idee zur praktischen Umsetzung schlussfolgern zu können. Aufgrund dessen fällt die interprofessionelle Zusammenarbeit in unterschiedlichen Institutionen uneinheitlich aus.
Additional file 1: Figure S1. of Paediatric medical emergency calls to a Danish Emergency Medical Dispatch Centre: a retrospective, observational study
Creators: name: Andersen, Kasper
name: SĂ¸Ren Mikkelsen
name: JĂ¸Rgensen, Gitte
name: Zwisler, Stine
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Overview of the categories in the Danish Index for Emergency Care. A figure listing the 37 different categories in the criteria-based dispatch protocol used by the Danish EMDCs. (PDF 449Â kb)
Propagation of transition front in bi-stable nondegenerate chains: model dependence and universality
Creators: name: Shiroky, I. B.
name: Gendelman, O. V.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We consider a propagation of transition fronts in one-dimensional chains with bi-stable nondegenerate on-site potential. If one adopts linear coupling in the chain and piecewise linear on-site force, then it is possible to develop well-known exact solutions for the front and accompanying oscillatory tail. We demonstrate that these solutions are essentially non-robust. Various approximations for the on-site potential with the same basic parameters (height and coordinate of the potential barrier, energy effect and distance between the potential wells) lead to substantially different front velocities. Besides, inclusion of even weak nearest neighbor nonlinearity drastically modifies the front structure and parameters. The energy concentration in the front zone leads to a dominance of the nonlinear term. It turns out that the dynamics can be efficiently studied in terms of an equivalent model with a single degree of freedom. This estimation leads to accurate prediction of the front velocity and parameters of the oscillatory tail. Moreover, it turns out that the solution is robust - exact shape of the on-site potential weakly effects the front parameters. This finding also conforms to the simplified model, since the latter invokes only the general shape characteristics of the on-site potential.
Additional file 1: of What works in falls prevention in Asia: a systematic review and meta-analysis of randomized controlled trials
Creators: name: Hill, Keith
name: Plaiwan Suttanon
name: Sang-I Lin
name: Tsang, William W.N.
name: Asmidawati Ashari
name: Tengku Hamid
name: Farrier, Kaela
name: Burton, Elissa
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Biotechnology
Science Policy

description: PRISMA checklist. (DOC 64 kb)
Additional file 2 of GsERF1 enhances Arabidopsis thaliana aluminum tolerance through an ethylene-mediated pathway
Creators: name: Li, Lu
name: Li, Xingang
name: Yang, Ce
name: Cheng, Yanbo
name: Cai, Zhandong
name: Nian, Hai
name: Ma, Qibin
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 2.
Teucrium flavum subvar. mairei Litard.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Lamiaceae
Teucrium
Teucrium flavum
Teucrium flavum subvar. mairei litard.

description: Teucrium flavum subvar. mairei Litard. in Briq. & Litard., Prodr. Fl. Corse 3(2): 139. 1955.
Lectotypus (hic designatus): FRANCE. Corse: Bonifacio, à Canetto, 15.VII.1880, Reverchon 333 (G-BU [G00830047]!).
= Teucrium flavum L. subsp. flavum
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 72, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
Global Energetics of Solar Flares: VI. Refined Energetics of Coronal Mass Ejections
Creators: name: Aschwanden, Markus J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: In this study we refine a CME model presented in an earlier study on the global energetics of solar flares and associated CMEs, and apply it to all (860) GOES M- and X-class flare events observed during the first 7 years (2010-2016) of the Solar Dynamics Observatory (SDO) mission, which doubles the statistics of the earlier study. The model refinements include: (1) the CME geometry in terms of a 3D sphere undergoing self-similar adiabatic expansion; (2) the inclusion of solar gravitational deceleration during the acceleration and propagation of the CME, which discriminates eruptive and confined CMEs; (4) a self-consistent relationship between the CME center-of-mass motion detected during EUV dimming and the leading-edge motion observed in white-light coronagraphs; (5) the equi-partition of the CME kinetic and thermal energy; and (6) the Rosner-Tucker-Vaiana (RTV) scaling law. The refined CME model is entirely based on EUV dimming observations (using AIA/SDO data) and complements the traditional white-light scattering model (using LASCO/SOHO data), and both models are independently capable to determine fundamental CME parameters such as the CME mass, speed, and energy. Comparing the two methods we find that: (1) LASCO is less sensitive than AIA in detecting CMEs (in 24$\%$ of the cases); (2) CME masses below $m_{cme} \sim 10^{14}$ g are under-estimated by LASCO; (3) AIA and LASCO masses, speeds, and energy agree closely in the statistical mean after elimination of outliers; (4) the CMEs parameters of the speed $v$, emission measure-weighted flare peak temperature $T_e$, and length scale $L$ are consistent with the following scaling laws (derived from first principles): $v \propto T_e^{1/2}$, $v \propto (m_{cme})^{1/4}$, and $m_{cme} \propto L^2$.
description: 31 pages, 10 Figures
Logopädische Diagnostik bei Kindergartenkindern mit Deutsch als Zweitsprache in den Kantonen Luzern und Zürich Ein Blick in die Praxis mittels Befragung von Praktikerinnen und Praktikern
Creators: name: Lissoni, Laura
Publisher: name: Zenodo
Year: 2018
Subjects: Logopädie
Deutsch
Diagnostik
Vorschulerziehung
Bachelorarbeit

description: Die vorliegende Arbeit untersucht, wie in der logopädischen Praxis zwischen Therapiebedarf und Förderbedarf bei mehrsprachigen Kindergartenkindern unterschieden wird. Der Theorieteil erklärt, weshalb Mehrsprachigkeit aus fachlicher Sicht eine Herausforderung für die Logopädie darstellt. Mittels Umfragebogen wurden Logopädinnen zu ihrem Vorgehen bei Abklärungen sowie zur Relevanz der Mehrsprachigkeit im Alltag befragt. Die gewonnenen Daten wurden qualitativ und quantitativ ausgewertet. Die Ergebnisse zeigten eine grosse Diversität im diffe-renzialdiagnostischen Vorgehen der Befragten. Diese Bilanz kann auf eine bescheiden entwi-ckelte evidenzbasierte Praxis hindeuteten. Es scheint jedoch trotzdem, dass Praktikerinnen1 kompetente, auf Erfahrungswerten basierende Lösungen für den Umgang mit der Mehrspra-chigkeit gefunden haben.
Clinical outcomes of ALK+ non-small cell lung cancer in Denmark
Creators: name: Hansen, Karin Holmskov
name: Johansen, Jakob Sidenius
name: Urbanska, Edyta Maria
name: Meldgaard, Peter
name: Hjorth-Hansen, Peter
name: Kristiansen, Charlotte
name: Stelmach, Miroslaw
name: Santoni-Rugiu, Eric
name: Ulhøi, Maiken Parm
name: Dydensborg, Anders Bondo
name: Dünweber, Christina
name: Andersen, Jon Lykkegaard
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Real-world clinical outcomes of anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (NSCLC) patients vary. This study aimed to investigate the treatment and clinical outcomes of all ALK+ NSCLC patients in Denmark in the period 2011–2018, regardless of disease stage. A national pathology database with complete coverage was used to identify ALK+ NSCLC patients diagnosed between 2011 and 2018. Clinical data were obtained through retrospective chart reviews. Overall survival (OS) and duration of treatment (DOT) were analyzed using Kaplan-Meier methodologies. A total of 209 ALK+ NSCLC patients were included. The cohort had a slight overrepresentation of female patients (56.5%) with a mean age of 61.6 years. Most patients were adenocarcinoma cases (97%) and presented with an ECOG performance status of 0–1 (79%). Stage IIIb–IVb patients comprised 70% of the cohort. The use of ALK-tyrosine kinase inhibitors (TKIs) as first-line treatment increased over time, with the 1st generation ALK-TKI crizotinib being the predominant treatment in the 1st line. In 1st line treatment, 2nd generation ALK-TKIs had a median DOT more than twice the median DOT of crizotinib (25.1 and 9.1 months, respectively). The median OS for the entire cohort was 44.0 months. Patients with stage I–IIIA disease had a median OS that had not been reached, while those with stage IIIb–IVb disease had a median OS of 31.8 months. Patients with stage IIIb–IVb disease receiving an ALK-TKI as 1st line treatment had a median OS of 42.5 months with immature follow-up. Brain metastases at diagnosis or choice of 1st line treatment did not statistically significantly impact OS. This study gives insights into the treatment and outcome of ALK+ NSCLC patients in Denmark and provides a real-world confirmation of the superior disease control provided by 2nd generation ALK-TKIs as compared to the 1st generation ALK-TKI crizotinib.
Generalized Skyrmions and hairy black holes in asymptotically AdS$_4$ spacetime
Creators: name: Perapechka, Ilya
name: Shnir, Yakov
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the properties of spherically symmetric black hole solutions in the generalized Einstein-Skyrme model theory in four-dimensional asymptotically anti-de Sitter space-time. The dependencies of the Skyrmion fields on the cosmological constant and on the strength of the effective gravitational coupling are examined. We show that the increase of the absolute value of the cosmological constant qualitatively yields the same effect as increasing of the effective gravitational coupling. We confirm that, similar to the model in the asymptotically flat space-time, a necessary condition for the existence of black holes with Skyrmionic hair is the inclusion of the Skyrme term.
description: 23 pages, 15 figures
Analysis of quantum tomography protocol efficiency for triphoton polarization states
Creators: name: Bogdanov, Yu. I.
name: Kuznetsov, Yu. A.
name: Avosopyants, G. V.
name: Katamadze, K. G.
name: Belinsky, L. V.
name: Borshchevskaya, N. A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Reliable generation and measurement of triphoton states has yet to be achieved in laboratory. We give an overview of the problems in generating and measuring triphoton quantum states and analyze several protocols of quantum measurements, which allow for high precision of reconstruction when sizes of available statistical data samples are limited. The tomography procedure under investigation is based on root approach to state estimation. In particular, we use the generalized Fisher information matrix to assess the accuracy of the quantum state parameters measurement. We use tomographic protocols, based on the symmetry of the Platonic solids. We demonstrate the capability to reconstruct triphoton quantum states with precision close to the maximum achievable value allowed by quantum mechanics
description: 11 pages, 5 figures. International Conference on Micro- and Nano-Electronics 2016. Zvenigorod, Russian Federation, October 3-7, 2016
Additional file 2 of Clinical significance of peripheral blood-derived inflammation markers in advanced gastric cancer after radical resection
Creators: name: Gu, Lihu
name: Wang, Mian
name: Cui, Xuena
name: Mo, Jiahang
name: Yuan, Lingling
name: Mao, Feiyan
name: Zhang, Kang
name: Ng, Derry Minyao
name: Chen, Ping
name: Wang, Dongjie
Publisher: name: figshare
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology

description: Additional file 2: Table S2. Optimal cutoff analysis.
Logopädische Diagnostik im Frühbereich: alleine oder zu zweit? Das direkte Vier-Augen-Prinzip
Creators: name: Erhardt, Inez
Publisher: name: Zenodo
Year: 2018
Subjects: Logopädie
Diagnostik
Bachelorarbeit

description: Die logopädische Abklärung im Frühbereich ist eine schwierige Aufgabe: Beobachten und gleichzeitig Protokoll führen. Wieso teilt man sich diese Aufgabe nicht? Vier Augen sehen mehr. In der Fachliteratur und in der Praxis findet sich dieses Modell selten. In einer Fallstudie wird ein dreistufiges Vorgehen gewählt: eine schriftliche Befragung, ein Partnerinterview und ein Einzelinterview. Die Resultate der Befragung dienen als Basis für den Leitfaden für die Interviews. Die Interviews werden qualitativ mittels inhaltlich strukturierter Inhaltsanalyse nach Kuckartz (2012) ausgewertet und die Resultate zu einer sequentiellen Befragtentriangulation zusammengeführt. Die Abklärung im direkten Vier-Augen-Prinzip stellt sich in dieser Fallstudie als nicht kostenintensiver als die Abklärung alleine dar. Die Qualitätskriterien dienen direkt der Qualitätssicherung.
Additional file 5: of The influence of maternal psychosocial circumstances and physical environment on the risk of severe wasting in rural Gambian infants: a mixed methods approach
Creators: name: Nabwera, Helen
name: Moore, Sophie
name: Mwangome, Martha
name: Sassy Molyneux
name: Momodou Darboe
name: Nyima Camara-Trawally
name: Bakary Sonko
name: Alhagie Darboe
name: Seedy Singhateh
name: Fulford, Anthony
name: Prentice, Andrew
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: Tool for to support interviews with fathers (DOCX 67 kb)
(Sub)millimetre observations of z>6 quasar hosts: massive galaxy formation in the epoch of reionisation
Creators: name: Venemans, Bram
Publisher: name: Zenodo
Year: 2020

description: Quasars are the brightest (non-transient) objects observed at the highest redshifts, z>7, which makes them unique probes of the evolution of black holes, massive galaxies and the intergalactic medium. While at (observed) optical and near-infrared wavelengths the central point sources outshine the host galaxies of these bright quasars, observations in the millimetre can constrain the gas and dust content in these galaxies. In recent years numerous quasars at z>6 and up to z=7.5 have been discovered. In this talk I will review the results of a number of ALMA and NOEMA programmes to study the host galaxies of z>6 quasars. I will discuss the implications of the findings on massive galaxy formation, the black hole - galaxy coevolution and the environment of high redshift quasars.
Teucrium marum subvar. drosocalyx Litard.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Lamiaceae
Teucrium
Teucrium marum
Teucrium marum subvar. drosocalyx litard.

description: Teucrium marum subvar. drosocalyx Litard. in Briq. & Litard., Prodr. Fl. Corse 3(2): 145. 1955.
Lectotypus (hic designatus): FRANCE. Corse: Mont Felce près de Corte, VII.1898, Mandon & Foucaud 4317 (G-BU [G00830128]!). Syntypi: (G-BU [G00830126, G00830127, G00830129, G00830130]!).
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 72, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
Low Rank Matrix Recovery with Simultaneous Presence of Outliers and Sparse Corruption
Creators: name: Rahmani, Mostafa
name: Atia, George
Publisher: name: arXiv
Year: 2017
Subjects: subject: Machine Learning (stat.ML)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: We study a data model in which the data matrix D can be expressed as D = L + S + C, where L is a low rank matrix, S an element-wise sparse matrix and C a matrix whose non-zero columns are outlying data points. To date, robust PCA algorithms have solely considered models with either S or C, but not both. As such, existing algorithms cannot account for simultaneous element-wise and column-wise corruptions. In this paper, a new robust PCA algorithm that is robust to simultaneous types of corruption is proposed. Our approach hinges on the sparse approximation of a sparsely corrupted column so that the sparse expansion of a column with respect to the other data points is used to distinguish a sparsely corrupted inlier column from an outlying data point. We also develop a randomized design which provides a scalable implementation of the proposed approach. The core idea of sparse approximation is analyzed analytically where we show that the underlying ell_1-norm minimization can obtain the representation of an inlier in presence of sparse corruptions.
Phonon linewidth due to electron-phonon interactions with strong forward scattering in FeSe thin films on oxide substrates
Creators: name: Wang, Yan
name: Rademaker, Louk
name: Dagotto, Elbio
name: Johnston, Steven
Publisher: name: arXiv
Year: 2017
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The discovery of an enhanced superconducting transition temperature $T_c$ in monolayers of FeSe grown on several oxide substrates has opened a new route to high-$T_c$ superconductivity through interface engineering. One proposal for the origin of the observed enhancement is an electron-phonon (e-ph) interaction across the interface that peaked at small momentum transfers. In this paper, we examine the implications of such a coupling on the phononic properties of the system. We show that a strong forward scattering leads to a sizable broadening of phonon lineshape, which may result in charge instabilities at long-wavelengths. However, we further find that the inclusion of Coulombic screening significantly reduces the phonon broadening. Our results show that one might not expect anomalously broad phonon linewidths in the FeSe interface systems, despite the fact that the e-ph interaction has a strong peak in the forward scattering (small $q$) direction.
description: 8 pages, 4 figures
Risk of prostate cancer death after radical radiotherapy with neoadjuvant and adjuvant therapy with bicalutamide or gonadotropin-releasing hormone agonists
Creators: name: Bonde, Tiago M.
name: Garmo, Hans
name: Stattin, Pär
name: Nilsson, Per
name: Gunnlaugsson, Adalsteinn
name: Swanberg, Daniela
name: Robinson, David
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Oncological outcome after radical radiotherapy (RRT) combined with neoadjuvant and adjuvant androgen suppression therapy (AST) may differ according to type of AST. The aim of this nationwide register-based study was to investigate risk of prostate cancer (Pca) death after different neoadjuvant and adjuvant ASTs; (i) bicalutamide, (ii) gonadotropin-releasing hormone agonists (GnRH) or (iii) combined bicalutamide and GnRH (CAB), together with RRT. Data for 6882 men diagnosed with high-risk Pca between 2007 and 2020 and treated with primary RRT was retrieved from Prostate Cancer data Base Sweden (PCBaSe) 5.0. Time to Pca death according to type of neoadjuvant and adjuvant AST was assessed by use of Kaplan–Meier plots and Cox proportional hazard models adjusted for putative confounders. Data were stratified by RRT type since the effect of AST in risk of Pca death differed according to type of RRT. Compared with the reference RRT combined with neoadjuvant CAB/adjuvant GnRH, risk of Pca death for men treated with CAB/bicalutamide and conventionally fractionated external beam radiotherapy (CF-EBRT) was hazard ratio (HR) 0.73 (95% CI: 0.50–1.04), hypofractionated EBRT (HF-EBRT), HR 1.35 (95% CI: 0.65–2.81) and EBRT with high dose rate brachytherapy (EBRT-HDRBT), HR 0.85 (95% CI: 0.37–1.95). Risk of Pca death for men treated with bicalutamide/bicalutamide and: (i) CF-EBRT was HR 2.35 (95% CI: 1.42–3.90), (ii) HF-EBRT, HR 0.70 (95% CI: 0.26–1.85), (iii) HF-EBRT, HR 4.07 (95% CI: 1.88–8.77) vs the reference. In this observational study, risk of Pca death between men receiving different combinations of AST varied according to RRT type. No difference was found in risk of Pca death for men treated with bicalutamide or GnRH as adjuvant therapy to RRT following neoadjuvant CAB. Risk of Pca death was increased for men with monotherapy neo-/adjuvant bicalutamide in combination with CF-EBRT or EBRT-HDRBT.
Interferenzen Eine Website mit den Gemeinsamkeiten und Unterschieden zwischen dem Hochdeutschen und den meist gesprochenen Sprachen in der Schweiz, Deutschland und Österreich
Creators: name: Remensberger, Caroline
name: Svaco, Ivana
Publisher: name: Zenodo
Year: 2018
Subjects: Logopädie
Sprache
Bachelorarbeit

description: Die vorliegende Arbeit stellt die Entwicklung und Evaluation der Website “Interferenzen” dar. Das Ziel war die Entwicklung eines Hilfsmittels, das Fachpersonen in der Arbeit mit mehrsprachigen Kindern in der Diagnostik unterstützt. Insbesondere sollte die Website helfen, grammatische “Fehler” bzw. Interferenzen in den Bereichen Morphologie und Syntax nicht sofort als Merkmale einer Spezifischen Spracherwerbsstörung zu bewerten. Im Rahmen der ersten Forschungsfrage wurde untersucht, wie eine Website, die die relevanten Unterschiede und Gemeinsamkeiten morphosyntaktischer Kategorien zwischen den meistgesprochenen Sprachen im deutschsprachigen Raum und dem Hochdeutschen dokumentiert, aufgebaut und präsentiert sein muss, damit Fachpersonen im Kindersprachbereich in der Diagnostik mehrsprachiger Kinder im Alter zwischen drei bis zehn Jahren unterstützt werden. Die Beantwortung dieser Frage erfolgte mittels eines Experteninterviews sowie Literaturrecherche. Zur Beantwortung der zweiten Forschungsfrage, wie die Navigation, der Inhalt und die Darstellung der Website “Interferenzen” eingeschätzt werden, wurden Fachpersonen in der Praxis anhand eines Think Aloud Tests und eines Leitfadeninterviews getestet und befragt. So konnte festgestellt werden, dass das Website sowohl in Bezug auf die Navigation als auch auf die Form und den Inhalt als ansprechend bewertet wurde.
Teucrium marum subvar. eriocalyx Litard.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Lamiaceae
Teucrium
Teucrium marum
Teucrium marum subvar. eriocalyx litard.

description: Teucrium marum subvar. eriocalyx Litard. in Briq. & Litard., Prodr. Fl. Corse 3(2): 144. 1955.
Lectotypus (hic designatus): FRANCE. Corse: vallée du Fango à Bastia, 18.VI.1866, Debeaux s.n. (G-BU [G00830118]!; isolecto-: G-BU [G00830119]!). Syntypi: (G [G00429955, G00429956, G00429957]!, G-BU [G00830120, G00830121, G00830122, G00830123, G00830124, G00830125]!).
= Teucrium marum L.
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 72, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
Thymelaea tarton-raira subvar. transiens Briq.
Creators: name: Jeanmonod, Daniel
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malvales
Thymelaeaceae
Thymelaea
Thymelaea tarton-Raira
Thymelaea tarton-Raira subvar. transiens briq.

description: Thymelaea tarton-raira subvar. transiens Briq. in Briq. & Litard., Prodr. Fl. Corse 3(1): 4. 1938.
Ξ Thymelaea tarton-raira subsp. transiens (Briq.) Gamisans
Lectotypus (hic designatus): FRANCE. Corse: sommet du Pigno sur le sentier de Farinola, 10.V.1866, Mabille s.n. (G-BU [G00830091]!). Syntypi: (G-BU [G00830096, G00830097]!).
description: Published as part of Jeanmonod, Daniel, 2018, Typification des noms de taxons corses de l'herbier Burnat (G-BU), pp. 61-74 in Candollea 73 (1) on page 72, DOI: 10.15553/c2018v731a6, http://zenodo.org/record/5722164
Additional file 4: of The influence of maternal psychosocial circumstances and physical environment on the risk of severe wasting in rural Gambian infants: a mixed methods approach
Creators: name: Nabwera, Helen
name: Moore, Sophie
name: Mwangome, Martha
name: Sassy Molyneux
name: Momodou Darboe
name: Nyima Camara-Trawally
name: Bakary Sonko
name: Alhagie Darboe
name: Seedy Singhateh
name: Fulford, Anthony
name: Prentice, Andrew
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: Tool to support interviews with mothers (DOCX 68 kb)
Defect processes in Be$_{12}$X Beryllides
Creators: name: Jackson, Matthew L
name: Burr, Patrick A
name: Grimes, Robin W
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The stability of intrinsic point defects in Be$_{12}$X intermetallics (where X = Ti, V, Mo or W) are predicted using density functional theory simulations and discussed with respect to fusion energy applications. Schottky disorder is found to be the lowest energy complete disorder process, closely matched by Be Frenkel disorder in the cases of Be$_{12}$V and Be$_{12}$Ti. Antitisite and X Frenkel disorder are of significantly higher energy. Small clusters of point defects including Be divacancies, Be di-interstitials and accommodation of the X species on two Be sites were considered. Some di-interstitial, divacancy and X$_{2Be}$ combinations exhibit negative binding enthalpy (i.e. clustering is favourable), although this is orientationally dependent. None of the Be$_{12}$X intermetallics are predicted to exhibit significant non-stoichiometry, ruling out non-stoichiometry as a mechanism for accommodating Be depletion due to neutron transmutation.
description: 15 pages, 3 figures
Predictors of preparedness for recovery following colorectal cancer surgery: a latent class trajectory analysis
Creators: name: Sawatzky, Richard
name: Larsdotter, Cecilia
name: Carlssson, Eva
name: Pettersson, Monica
name: Sarenmalm, Elisabeth Kenne
name: Smith, Frida
name: Nygren, Jonas
name: Russell, Lara
name: Öhlén, Joakim
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: With an interest in providing knowledge for person-centred care, our overall goal is to contribute a greater understanding of diversity among patients in terms of their preparedness before and up to six months after colorectal cancer surgery. Our aim was to describe and provide a tentative explanation for differences in preparedness trajectory profiles. The study was explorative and used prospective longitudinal data from a previously published intervention study evaluating person-centred information and communication. The project was conducted at three hospitals in Sweden. Patient-reported outcomes measures, including the Longitudinal Preparedness for Colorectal Cancer Surgery Questionnaire, were collected before surgery, at discharge, and four to six weeks, three months, and six months after surgery. Clinical data were retrospectively obtained from patients’ medical records. We used latent class growth models (LCGMs) to identify latent classes that distinguish subgroups of patients who represent different preparedness trajectory profiles. To determine the most plausible number of latent classes, we considered statistical information about model fit and clinical practice relevance. We used multivariable regression models to identify variables that explain the latent classes. The sample (N = 488) comprised people with a mean age of 68 years (SD = 11) of which 44% were women. Regarding diagnoses, 60% had colon cancer and 40% rectal cancer. The LCGMs identified six latent classes with different preparedness for surgery and recovery trajectories. The latent classes were predominantly explained by differences in age, sex, physical classification based on comorbidities, treatment hospital, global health status, distress, and sense of coherence (comprehensibility and meaningfulness). Contrary to the received view that emphasizes standardized care practices, our results point to the need for adding person-centred and tailored approaches that consider individual differences in how patients are prepared before and during the recovery period related to colorectal cancer surgery.