cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Multiport Y-Converter for Three-Phase AC Grid Integration with DC Systems
Creators: name: Abdelfattah, Ahmed Yahia Farag
Publisher: name: Zenodo
Year: 2024

description: Presentaion of a conference paper presented at the IEEE 15th International Symposium on Power Electronics for Distributed Generation Systems (PEDG 2024), Luxembourg held from June 23rd to June 26th, 2024.
Novel genes derived from noncoding DNA in Drosophila melanogaster are frequently X-linked and exhibit testis-biased expression
Creators: name: Kern, A. D.
name: Begun, D. J.
name: Levine, M. T.
name: Lindfors, H. A.
name: Jones, C. D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Descriptions of recently evolved genes suggest several mechanisms of origin including exon shuffling, gene fission/fusion, retrotransposition, duplication-divergence, and lateral gene transfer, all of which involve recruitment of preexisting genes or genetic elements into new function. The importance of noncoding DNA in the origin of novel genes remains an open question. We used the well annotated genome of the genetic model system Drosophila melanogaster and genome sequences of related species to carry out a whole-genome search for new D. melanogaster genes that are derived from noncoding DNA. Here, we describe five such genes, four of which are X-linked. Our RT-PCR experiments show that all five putative novel genes are expressed predominantly in testes. These data support the idea that these novel genes are derived from ancestral noncoding sequence and that new, favored genes are likely to invade populations under selective pressures relating to male reproduction.
Unsteady Thermal Throat Position under Acoustic Forcing
Creators: name:  F. OLIVON
name:   JE. DURAND
name:   A. GENOT
name:   E. PIOT
Publisher: name: Proceedings of the Aerospace Europe Conference - EUCASS - CEAS - 2023
Year: 2023
Subjects: RAMJET
THERMAL THROAT
DIABATIC FLOW
AEROACOUSTIC

description: The interactions between acoustics waves and the thermal throat in a simplified low-Mach dual-mode ramjet chamber are numerically investigated. The present study aims to understand the thermal throat function in the combustion instabilities observed in such engines. In this context, the ramjet nozzle is thermally choked due to the combustion, here modelled by a steady and imposed heat release distribution. A harmonic inlet velocity forcing is applied to analyze the motion of the thermal throat subjected to an acoustic field. Various amplitudes (1 %-50 % of the steady inlet velocity) and frequencies (50 Hz-1000 Hz) are explored. An empirical and mono-harmonic model is then proposed to describe this relationship between acoustics and thermal throat motion. The numerical simulations and the model results are then compared and limitations are highlighted.
Models of dark matter halos based on statistical mechanics: I. The classical King model
Creators: name: Chavanis, Pierre-Henri
name: Lemou, Mohammed
name: Méhats, Florian
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We consider the possibility that dark matter halos are described by the Fermi-Dirac distribution at finite temperature. This is the case if dark matter is a self-gravitating quantum gas made of massive neutrinos at statistical equilibrium. This is also the case if dark matter can be treated as a self-gravitating collisionless gas experiencing Lynden-Bell's type of violent relaxation. In order to avoid the infinite mass problem and carry out a rigorous stability analysis, we consider the fermionic King model. In this paper, we study the non-degenerate limit leading to the classical King model. This model was initially introduced to describe globular clusters. We propose to apply it also to large dark matter halos where quantum effects are negligible. We determine the caloric curve and study the thermodynamical stability of the different configurations. Equilibrium states exist only above a critical energy $E_c$ in the microcanonical ensemble and only above a critical temperature $T_c$ in the canonical ensemble. For $E
Order N algorithm for computation of electrostatic interactions in biomolecular systems
Creators: name: Huang, J.
name: Cheng, X.
name: McCammon, J. A.
name: Lu, B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Poisson–Boltzmann electrostatics is a well established model in biophysics; however, its application to large-scale biomolecular processes such as protein–protein encounter is still limited by the efficiency and memory constraints of existing numerical techniques. In this article, we present an efficient and accurate scheme that incorporates recently developed numerical techniques to enhance our computational ability. In particular, a boundary integral equation approach is applied to discretize the linearized Poisson–Boltzmann equation; the resulting integral formulas are well conditioned and are extended to systems with arbitrary numbers of biomolecules. The solution process is accelerated by Krylov subspace methods and a new version of the fast multipole method. In addition to the electrostatic energy, fast calculations of the forces and torques are made possible by using an interpolation procedure. Numerical experiments show that the implemented algorithm is asymptotically optimal O(N) in both CPU time and required memory, and application to the acetylcholinesterase–fasciculin complex is illustrated.
Heat fluctuations and initial ensembles
Creators: name: Kim, Kwangmoo
name: Kwon, Chulan
name: Park, Hyunggyu
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Time-integrated quantities such as work and heat increase incessantly in time during nonequilibrium processes near steady states. In the long-time limit, the average values of work and heat become asymptotically equivalent to each other, since they only differ by a finite energy change in average. However, the fluctuation theorem (FT) for the heat is found not to hold with the equilibrium initial ensemble, while the FT for the work holds. This reveals an intriguing effect of everlasting initial memory stored in rare events. We revisit the problem of a Brownian particle in a harmonic potential dragged with a constant velocity, which is in contact with a thermal reservoir. The heat and work fluctuations are investigated with initial Boltzmann ensembles at temperatures generally different from the reservoir temperature. We find that, in the infinite-time limit, the FT for the work is fully recovered for arbitrary initial temperatures, while the heat fluctuations significantly deviate from the FT characteristics except for the infinite initial-temperature limit (a uniform initial ensemble). Furthermore, we succeed in calculating finite-time corrections to the heat and work distributions analytically, using the modified saddle point integral method recently developed by us. Interestingly, we find non-commutativity between the infinite-time limit and the infinite-initial-temperature limit for the probability distribution function (PDF) of the heat.
description: 12 pages
p38MAPK inhibition prevents disease in pemphigus vulgaris mice
Creators: name: Liu, Z.
name: Hu, P.
name: Berkowitz, P.
name: Diaz, L. A.
name: Rubenstein, D. S.
name: Warren, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Pemphigus vulgaris (PV) is a life-threatening autoimmune blistering skin disease characterized by detachment of keratinocytes (acantholysis). It has been proposed that PV IgG might trigger signaling and that this process may lead to acantholysis. Indeed, we recently identified a rapid and dose-dependent phosphorylation of p38 mitogen-activated protein kinase (p38MAPK) and heat shock protein (HSP) 27 after binding of PV antibodies to cultured keratinocytes. In human keratinocyte cultures, inhibitors of p38MAPK prevented PV IgG-induced phosphorylation of HSP27 and, more importantly, prevented the early cytoskeletal changes associated with loss of cell–cell adhesion. This study was undertaken to (i) determine whether p38MAPK and HSP25, the murine HSP27 homolog, were similarly phosphorylated in an in vivo model of PV and (ii) investigate the potential therapeutic use of p38MAPK inhibition to block blister formation in an animal model of PV. We now report that p38MAPK inhibitors prevented PV blistering disease in vivo. Targeting the end-organ by inhibiting keratinocyte desmosome signaling may be effective for treating desmosome autoimmune blistering disorders.
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5
Creators: name: Thompson, C. L.
name: Shields, K. F.
name: Selby, C. P.
name: Sancar, A.
name: Partch, C. L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The molecular oscillator that drives circadian rhythmicity in mammals obtains its near 24-h periodicity from posttranslational regulation of clock proteins. Activity of the major clock kinase casein kinase I (CKI) ε is regulated by inhibitory autophosphorylation. Here we show that protein phosphatase (PP) 5 regulates the kinase activity of CKIε. We demonstrate that cryptochrome regulates clock protein phosphorylation by modulating the effect of PP5 on CKIε. Like CKIε, PP5 is expressed both in the master circadian clock in the suprachiasmatic nuclei and in peripheral tissues independent of the clock. Expression of a dominant-negative PP5 mutant reduces PER phosphorylation by CKIε in vivo, and down-regulation of PP5 significantly reduces the amplitude of circadian cycling in cultured human fibroblasts. Collectively, these findings indicate that PP5, CKIε, and cryptochrome dynamically regulate the mammalian circadian clock.
Elaboración de un recurso pedagógico a través de la implementación de un ambiente virtual de aprendizaje en Google Sites como repositorio para mejorar la competencia comunicativa lectora en el área de inglés de los estudiantes de grado tercero, en la Institución Educativa Técnica Agropecuaria José María Hernández del municipio de Pupiales - Nariño.
Creators: name: Paz Pantoja, Ana Cristina
Publisher: name: Universidad de Cartagena
Year: 2023
Subjects: subject: Juegos por Computador
subject: Inglés - Aprendizaje
subject: Inglés - Enseñanza con ayuda de computadores

description: Este proyecto tiene como objeto mejorar la competencia comunicativa lectora en el área de inglés de los estudiantes de grado tercero. Durante y después de la pandemia por covid19, como docentes y en la necesidad de estar a la par con la era digital actual, el aprendizaje de idiomas ha evolucionado drásticamente, y las herramientas tecnológicas se han convertido en aliados clave para mejorar las habilidades lingüísticas de los estudiantes. En particular, la competencia comunicativa lectora en inglés es de vital importancia para el desarrollo académico y profesional de los estudiantes. El ambiente virtual de aprendizaje en Google sites proporciona un entorno interactivo y colaborativo donde los estudiantes pueden practicar y mejorar sus habilidades a través de actividades y ejercicios para abordar las dificultades encontradas con la oportunidad de consolidar su conocimiento ampliar su vocabulario y fortalecer la comprensión lectora en inglés.
Applied Mechanics I (Main Stream) APM11P1 APM11B1
Creators: name: Valentyn, Brendin
name: Thankachan, Molly
Publisher: name: Walter Sisulu University
Year: 2022
Subjects: Civil engineering not elsewhere classified

description: Subject : Applied Mechanics Subject code : APM11P1 (BCC) & APM11B1 (IBIKA) Qualification : National Diploma Engineering: Civil Examiners : Mr. B Valentyn and Mrs. M. Thankachan Moderator : Mr MH Singata Date : June 2019
Spin-Hall Nano-oscillator: a micromagnetic study
Creators: name: Giordano, A.
name: Carpentieri, M.
name: Laudani, A.
name: Gubbiotti, G.
name: Azzerboni, B.
name: Finocchio, G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: This letter studies the dynamical behavior of spin-Hall nanoscillators from a micromagnetic point of view. The model parameters have been identified by reproducing recent experimental data quantitatively. Our results indicate that a strongly localized mode is observed for in-plane bias fields such as in the experiments, while predict the excitation of an asymmetric propagating mode for large enough out-of plane bias field similarly to what observed in spin-torque nanocontact oscillators. Our findings show that spin-Hall nanoscillators can find application as spin-wave emitters for magnonic applications where spin waves are used for transmission and processing information on nanoscale.
description: 14 pages
Quick-preliminary aerodynamic estimation for a distributed propulsion aircraft with propellers in front of the wing
Creators: name:  DAVID PLANAS
name:   ERIC NGUYEN VAN
name:   CARSTEN DOLL
name:   PHILIPPE PASTOR
Publisher: name: Proceedings of the Aerospace Europe Conference - EUCASS - CEAS - 2023
Year: 2023
Subjects: DISTRIBUTED PROPULSION
PRELIMINARY ESTIMATION
AERO-PROPULSIVE INTERACTION

description: The following paper presents the development and validation of a modeling for the quick estimation of the aerodynamic forces and moments of a distributed electric propulsion aircraft (DEP). The use of DEP concepts leads to new multidisciplinary interactions between the propulsion system and the lifting surfaces. These aero-propulsive couplings can be leveraged to enhance the overall capacities of the aircraft. In order to do so, they must, however, be well estimated during early design phases. To address this purpose, an aerodynamic modeling is proposed and built in Python. The module makes use of a post-modified Vortex Lattice Method. For validating the proposed modeling, several flight cases are faced against a Reynolds-averaged Navier Stokes flow solver. The chosen aircraft is the NASA\'s experimental X-57 Maxwell. Results prove to be sufficiently good for the use during preliminary design phases. In particular, for the powered analysis, with the propellers actively modifying the wing\'s aerodynamics, the lift coefficient can be estimated with a precision that is kept within 70/o for all the pre-stall linear region. The computation time is drastically reduced when compared with the CFD analysis, rendering the module suitable for an OAD optimization loop. Keywords: DEP, X-57, electric aircraft, propeller-wing interaction
Does Domestic Agricultural Production Strengthen Food Security?
Creators: name: Kim, Taehwa
name: Kim, Taehwa
Publisher: name: Unknown
Year: 2019
Subjects: subject: Food Security and Poverty
subject: Food Security
subject: Food Self-sufficiency Rate
subject: Food Riots

description: The concept of food security has gained increasing attention in the recent ten years. The Food and Agriculture Organization (FAO) defines that food security exists when all people can access food needed for a healthy and active life at all times. Achieving food security means the situation where sufficient food is available, food supply is relatively stable, and those in need of food can afford food at a reasonable cost. However, there are conflicting opinions about how to achieve food security. Agricultural exporting countries insist that the diversification of food sources and domestic self-reliance as well contributes to enhancing food security. On the other hand, agricultural importing countries emphasize food self-sufficiency for major crops, especially after experiencing the major food crises across the globe during the agflation period between 2006 and 2011. This study investigates whether domestic agricultural production contributes to strengthening food security. Using the panel data for food self-sufficiency rate, we analyzed domestic grain price and food riots, the effect of domestic food production on food security or the probability of food riots. The results show that the increase in food self-sufficiency strengthens food security and reduces the probability of food riots, while lower import tariffs do not.
Pregnane X receptor (PXR) activation: A mechanism for neuroprotection in a mouse model of Niemann-Pick C disease
Creators: name: Walkley, S. U.
name: Langmade, S. J.
name: Schaffer, J. E.
name: Suzuki, K.
name: Ory, D. S.
name: Mohri, I.
name: Frolov, A.
name: Covey, D. F.
name: Gale, S. E.
name: Mellon, S. H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Niemann–Pick type C1 (NPC1) disease is a fatal neurodegenerative disease characterized by neuronal lipid storage and progressive Purkinje cell loss in the cerebellum. We investigated whether therapeutic approaches to bypass the cholesterol trafficking defect in NPC1 disease might delay disease progression in the npc1−/− mouse model. We show that the neurosteroid allopregnanolone (ALLO) and T0901317, a synthetic oxysterol ligand, act in concert to delay onset of neurological symptoms and prolong the lifespan of npc1−/− mice. ALLO and T0901317 therapy preserved Purkinje cells, suppressed cerebellar expression of microglial-associated genes and inflammatory mediators, and reduced infiltration of activated microglia in the cerebellar tissue. To establish whether the mechanism of neuroprotection in npc1−/− mice involves GABAA receptor activation, we compared treatment of natural ALLO and ent-ALLO, a stereoisomer that has identical physical properties of natural ALLO but is not a GABAA receptor agonist. ent-ALLO provided identical functional and survival benefits as natural ALLO in npc1−/− mice, strongly supporting a GABAA receptor-independent mechanism for ALLO action. On the other hand, the efficacy of ALLO, ent-ALLO, and T0901317 therapy correlated with the ability of these compounds to activate pregnane X receptor-dependent pathways in vivo. These findings suggest that treatment with pregnane X receptor ligands may be useful clinically in delaying the progressive neurodegeneration in human NPC disease.
Nonlinear Fluctuating Hydrodynamics in One Dimension: the Case of Two Conserved Fields
Creators: name: Spohn, Herbert
name: Stoltz, Gabriel
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the BS model, which is a one-dimensional lattice field theory taking real values. Its dynamics is governed by coupled differential equations plus random nearest neighbor exchanges. The BS model has exactly two locally conserved fields. Through numerical simulations the peak structure of the steady state space-time correlations is determined and compared with nonlinear fluctuating hydrodynamics, which predicts a traveling peak with KPZ scaling function and a standing peak with a scaling function given by the completely asymmetric Levy distribution with parameter $α= 5/3$. As a by-product, we completely classify the universality classes for two coupled stochastic Burgers equations with arbitrary coupling coefficients.
Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2
Creators: name: Huang, T.-Y.
name: Williams, J.
name: Stafford, D. W.
name: Chu, P.-H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: More than 21 million prescriptions for warfarin are written yearly in the U.S. Despite its importance, warfarin's target, vitamin K epoxide reductase (VKOR), has resisted purification since its identification in 1972. Here, we report its purification and reconstitution. HPC4, a calcium-specific antibody that recognizes a 12-aa tag, was used to purify and identify VKOR. Partial reconstitution is achieved on the column by washing with 0.4% dioleoylphosphatidylcholine/0.4% deoxycholate. Activity is completely recovered by dialysis against a buffer containing a reducing agent but lacking dioleoylphosphatidylcholine/deoxycholate. Removal of detergent from the eluted proteins apparently facilitates liposome formation. Purified recombinant VKOR with tag is ≈21 kDa, as expected; fully active; and >93% pure. The concentration of warfarin for 50% inhibition is the same for purified protein and microsomes. It has been reported that VKOR is a multisubunit enzyme. Our results, however, suggest that a single peptide can accomplish both the conversion of vitamin K epoxide to vitamin K and vitamin K to reduced vitamin K. This purification will allow further characterization of VKOR in relation to other components of the vitamin K cycle and should facilitate its structural determination.
Yaaliakeisy como propuesta basada en el diseño universal del aprendizaje y la realidad aumentada para el fortalecimiento de la competencia digital en estudiantes indígenas de la comunidad Piapoco del grado 4 de una Institución Educativa triétnica.
Creators: name: Galeano González, Ayaneth
Publisher: name: Universidad de Cartagena
Year: 2023
Subjects: subject: Computadores - Aplicaciones
subject: Informatica - Estudios y enseñanza
subject: Innovación pedagógica - Métodos de enseñanza

description: Este proyecto tiene como objeto las competencias digitales en estudiantes indígenas de la comunidad piapoco de grado 4 en la Institución Educativa triétnica Yaaliakeisy, mediante una propuesta basada en el diseño universal del aprendizaje(DUA) y la realidad aumentada (RA). Dentro de los resultados se encuentra que los estudiantes responden de manera efectiva a cada una de las actividades asignadas, añadiendo un progreso en el uso de los entornos virtuales a los que tienen acceso y hacen reconocimiento de algunos elementos del software, existiendo aportes de aspectos que no fueron planteados como el elemento motivante, la parte de la comprensión lectora y la interacción entre pares.
Nutzungsbedingungen und Lizenz für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH)
Creators: name: Wörner, Kai
Publisher: name: Universität Hamburg
Year: 2019
Subjects: invenio
fdm
rdm
uhh

description: Die Nutzungsbedingungen für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH) unter https://www.fdr.uni-hamburg.de/
Repair of DNA-polypeptide crosslinks by human excision nuclease
Creators: name: Sancar, A.
name: Reardon, J. T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: DNA–protein crosslinks are relatively common DNA lesions that form during the physiological processing of DNA by replication and recombination proteins, by side reactions of base excision repair enzymes, and by cellular exposure to bifunctional DNA-damaging agents such as platinum compounds. The mechanism by which pathological DNA–protein crosslinks are repaired in humans is not known. In this study, we investigated the mechanism of recognition and repair of protein–DNA and oligopeptide–DNA crosslinks by the human excision nuclease. Under our assay conditions, the human nucleotide excision repair system did not remove a 16-kDa protein crosslinked to DNA at a detectable level. However, 4- and 12-aa-long oligopeptides crosslinked to the DNA backbone were recognized by some of the damage recognition factors of the human excision nuclease with moderate selectivity and were excised from DNA at relatively efficient rates. Our data suggest that, if coupled with proteolytic degradation of the crosslinked protein, the human excision nuclease may be the major enzyme system for eliminating protein–DNA crosslinks from the genome.
Tidal deformations of spinning black holes in Bowen-York initial data
Creators: name: Cabero, Miriam
name: Krishnan, Badri
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study the tidal deformations of the shape of a spinning black hole horizon due to a binary companion in the Bowen-York initial data set. We use the framework of quasi-local horizons and identify a black hole by marginally outer trapped surfaces. The intrinsic horizon geometry is specified by a set of mass and angular-momentum multipole moments $\mathcal{M}_n$ and $\mathcal{J}_n$ respectively. The tidal deformations are described by the change in these multipole moments caused by an external perturbation. This leads us to define two sets of dimensionless numbers, the tidal coefficients for $\mathcal{M}_n$ and $\mathcal{J}_n$, which specify the deformations of a black hole with a binary companion. We compute these tidal coefficients in a specific model problem, namely the Bowen-York initial data set for binary black holes. We restrict ourselves to axisymmetric situations and to small spins. Within this approximation, we analytically compute the conformal factor, the location of the marginally trapped surfaces, and finally the multipole moments and the tidal coefficients.
description: 22 pages, 1 figure
Resistive MHD simulations of a self-field Magneto Plasma Dynamic thruster over the 5 to 40 kA current range
Creators: name:  YEVHEN TKACHENKO
name:   ANDREA CIARDI
name:   BENJAMIN KHIAR
Publisher: name: Proceedings of the Aerospace Europe Conference - EUCASS - CEAS - 2023
Year: 2023
Subjects: ELECTRIC PROPULSION
MAGNETO PLASMA DYNAMIC THRUSTERS
NUMERICAL SIMULATIONS
MAGNETOHYDRODYNAMICS

description: Self-field magnetoplasmadynamic thrusters (MPDTs) are a promising class of electric space propulsion (EP) devices. The acceleration of the plasma propellant in MPDTs is mostly done by the Lorentz force produced by the interaction of the discharge current and the induced (self) magnetic field. Despite its unique ability among EP devices to efficiently handle very high power levels with a relatively simple design, the wide spread use of self-field MPDTs is limited, in addition to the currently unavailable high power sources, by the \"onset\": an unstable plasma behaviour that is experimentally observed for currents above a critical current. In this paper we investigate numerically the plasma dynamics of argon self-field MPDTs over a wide range of currents (J = 5 -40 kA) including super-critical ones Uc 17 kA). We perform single-fluid, two temperature, resistive magnetohydrodynamic (MHD) simulations in 2D cylindrical axisymmetric geometry. The simulations recover the expected values of the thrust for the two known operational regimes of MPDTs, with the acceleration of the plasma being pressure-driven at low currents and magneticallydriven at high currents. The power at high currents follows the expected scaling . 14 . We find that while the physical model employed recovers well the expected dynamics of MPDTs, for currents above the critical current le the simulations show instead stable plasma behaviour. The results indicate that to trigger the \"onset\", simulations will need to include more physical processes, as well as being extended to three-dimensions.
Nutzungsbedingungen und Lizenz für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH)
Creators: name: Wörner, Kai
Publisher: name: Universität Hamburg
Year: 2019
Subjects: invenio
fdm
rdm
uhh
terms of use
nutzungsbedingungen

description: Die Nutzungsbedingungen für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH) unter https://www.fdr.uni-hamburg.de/
Propuesta de educación artística mediada por la creación de una página web para fortalecimiento de las competencias lingüísticas en los estudiantes del grado 10°1 de la Institución Educativa Nechí .
Creators: name: Charris Romero, Jaminton Javier
name: Villalobos Fuentes, Luz Aurora
name: Gómez Montes, David Mauricio
name: Espinosa Escobar, Maria Eugenia
Publisher: name: Universidad de Cartagena
Year: 2023
Subjects: subject: Herramientas virtuales
subject: Lingüística - Enseñanza
subject: Educación artistica

description: Este proyecto tiene como objeto fortalecer las competencias lingüísticas por medio del área de educación artística; además, posibilitar la implementación de un recurso educativo digital innovadora con ayuda de la tecnología, herramientas que ayudan en la publicación de un material de conocimiento y didáctico, para fortalecer los procesos de enseñanza – aprendizaje, fundamentada en el análisis cualitativo, identificado como un ejercicio coherente determinado para comprender a fondo cuales son los fenómenos sociales y educativos. se concluye dinamizar entre los estudiantes la realización de actividades en las clases que contengan más pensamiento lógico y el desarrollo del lenguaje; para así desarrollar las competencias lingüísticas que ayudará el acceso a diferentes contenidos curriculares en todos los campos educativos, pues se trata del elemento fundamental para más adelante aplicarlo a futuro.
Selection and analysis of spontaneous reciprocal mitotic cross-overs in Saccharomyces cerevisiae
Creators: name: Petes, T. D.
name: Barbera, M. A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: We developed a system that allows the selection of the reciprocal products resulting from spontaneous mitotic cross-overs in the yeast Saccharomyces cerevisiae. A number of other types of genetic events, including chromosome loss, can be monitored with this system. For a 120-kb chromosome interval on chromosome V (CEN5-CAN1), the rate of mitotic cross-overs was 4 × 10−5 per division, a rate ≈25,000-fold lower than the meiotic rate of cross-overs. We found no suppression of mitotic cross-overs near the centromere of chromosome V, unlike the suppression observed for meiotic exchanges. The rate of reciprocal cross-overs was substantially (38-fold) elevated by treatment of cells with hydroxyurea, a drug that reduces nucleotide pools and slows DNA replication.
Southeast Washington Cooperative River Basin Study
Creators: name: Soil Conservation Service
name: Service, Forest
name: Economic Research Service
name: Soil Conservation Service
name: Service, Forest
name: Economic Research Service
Publisher: name: Unknown
Year: 1984
Subjects: Crop Production/Industries
Environmental Economics and Policy
Labor and Human Capital
Land Economics/Use
Livestock Production/Industries
Productivity Analysis
Resource /Energy Economics and Policy

description: The Southeast Washington River Basin Study area, located in southeast Washington State, encompasses 2,785,081 acres (4,351 square miles). All of Asotin, Garfield, Columbia, and Walla Walla Counties and parts of Franklin and Whitman Counties are included in the study area. The State of Washington, through the Washington State Department of Ecology, Washington State Conservation Commission, and Conservation Districts in Washington State, requested that the Southeast Washington River Basin Study be performed. Major study objectives included: • Basin-wide evaluation of erosion and sediment problems, present land management and stream habitat condition. • Intensive study of the Tucannon River, to determine instream effects of erosion and sediment on water quality and stream habitat conditions. • Evaluation of impacts of conservation practices and land use change as applicable to cropland and forested areas and production practices on rangeland areas in the basin. • Obtain local guidance and input to the study and provide the user groups meaningful data resulting from the study findings. The results of this study are presented in four types of reports: this summary document, ten individual watershed reports, an appendix, and two separate reports relating directly to the special Tucannon River instream investigation.
description: This study was performed by the U.S. Department of Agriculture (U.S.D.A.). U.S.D.A. agencies cooperating in the study were the Soil Conservation Service, Forest Service and Economic Research Service. Washington State Department of Ecology has assisted U.S.D.A. in study administration, coordination and direction. It is authorized by Section 6 of the Watershed Protection and Flood Prevention Act, (Public Law 566, 83rd Congress, 68 Stat. 666 as amended).
The Effect of School Dietary Education on Adolescent Fruit and Vegetable Intake
Creators: name: Yeon, Kwanghun
name: Yeon, Kwanghun
Publisher: name: Unknown
Year: 2019
Subjects: subject: Food Consumption/Nutrition/Food Safety
subject: School Dietary Education
subject: Selection Bias
subject: Policy Evaluation

description: In 2010, the Korean government implemented a school dietary education policy to improve people’s dietary habits. This policy included dietary education for adolescents in school. However, its effect on adolescents’ eating habits is unclear. The objective of this study is to examine the effect of school dietary education on adolescents’ fruit and vegetable consumption. We used the thirteenth Korea Youth Risk Behavior Web-based Survey in 2017. Also, we used the Matching Frontier Method to control the selection bias. The results suggest that school dietary education makes a positive impact on adolescents’ daily consumption of fruits and vegetables recommended. Consuming at least a fruit a day is likely to increase by 2.2%p-4.0%p and consuming vegetables at least three times a day is likely to increase by 1.5%p-2.8%p. These results imply that school dietary education is an effective policy to develop healthy eating habits among adolescents.
Structure of an RNA switch that enforces stringent retroviral genomic RNA dimerization
Creators: name: Badorrek, C. S.
name: Gherghe, C. M.
name: Weeks, K. M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Retroviruses selectively package two copies of their RNA genomes in the context of a large excess of nongenomic RNA. Specific packaging of genomic RNA is achieved, in part, by recognizing RNAs that form a poorly understood dimeric structure at their 5′ ends. We identify, quantify the stability of, and use extensive experimental constraints to calculate a 3D model for a tertiary structure domain that mediates specific interactions between RNA genomes in a gamma retrovirus. In an initial interaction, two stem–loop structures from one RNA form highly stringent cross-strand loop–loop base pairs with the same structures on a second genomic RNA. Upon subsequent folding to the final dimer state, these intergenomic RNA interactions convert to a high affinity and compact tertiary structure, stabilized by interdigitated interactions between U-shaped RNA units. This retroviral conformational switch model illustrates how two-step formation of an RNA tertiary structure yields a stringent molecular recognition event at early assembly steps that can be converted to the stable RNA architecture likely packaged into nascent virions.
title: Research output of Morningside Graduate School of Biomedical Sciences faculty: A visual review
Creators: name: Grynoch, Catherine Tess
name: Honor, Leah
name: Gore, Sally
name: Palmer, Lisa
Publisher: name: eScholarship@UMassChan
Year: 2023

description: Research metrics can be used to demonstrate individual research output but also the research output of a group and their contributions to scientific effort. Traditional research metrics have been limited to publication and citation counts and journal impact measures. New tools allow for a broader perspective and an exploration of public engagement with the inclusion of altmetrics such as mentions in traditional and social media, citations in policy documents, and downloads. Similarly, network analysis of bibliometric data can demonstrate the power of co-authorship and collaboration, as well as reveal trending topics. By using the 2020-2022 research output of current Morningside Graduate School of Biomedical Sciences faculty, what conclusions can be drawn by seeing all these metrics visually? This poster will display a variety of research metrics and discuss the strengths and weaknesses of each.
Nutzungsbedingungen und Lizenz für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH)
Creators: name: Wörner, Kai
Publisher: name: Universität Hamburg
Year: 2019
Subjects: invenio
fdm
rdm
uhh

description: Die Nutzungsbedingungen für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH) unter https://www.fdr.uni-hamburg.de/ Das hier
Eco-efficient manufacturing of horizontal tail plane (HTP) structures for next-generation aircrafts the role of surface pretreatment for adhesive joints
Creators: name:  U. LOMMATZSCH
name:   B. SCHNEIDER
name:   K. THIEL
name:   F. DE LA ESCALERA
Publisher: name: Proceedings of the Aerospace Europe Conference - EUCASS - CEAS - 2023
Year: 2023
Subjects: SURFACES
ADHESIVE BONDING
PRETREATMENT

description: friction. A key technical issue is to build the HLFC structure as light and as cost-efficient as possible. This goal can be achieved by adhesive bonding of a microperforated titanium panel to a composite substructure. High demands on the durability of the adhesive joint exist, requiring adequate surface pretreatment. Here we report on the pretreatment to improve bond strength and bond durability by laser as a pretreatment alternative to chemical tank processing consuming large amounts of energy and harmful chemicals. Surfaces are analyzed by XPS and SEM while fracture toughness is determined from DCB testing. In addition, the successful manufacturing demonstration of the laser pretreatment on an industrial scale is shown.
Nutzungsbedingungen und Lizenz für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH)
Creators: name: Wörner, Kai
Publisher: name: Universität Hamburg
Year: 2022
Subjects: invenio
fdm
rdm
uhh
terms of use
nutzungsbedingungen

description: Die Nutzungsbedingungen für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH) unter https://www.fdr.uni-hamburg.de/ Eine Englische Version ist unter https://doi.org/10.25592/uhhfdm.10120 verfügbar. Liste der Änderungen: 6.0: Kurationsprozess präzisiert. Für die Quelldatei HTML durch Markdown ersetzt. 5.1: Fehler korrigiert, HTML-Version hinzugefügt.
Nutzungsbedingungen und Lizenz für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH)
Creators: name: Wörner, Kai
Publisher: name: Universität Hamburg
Year: 2022
Subjects: invenio
fdm
rdm
uhh
terms of use
nutzungsbedingungen

description: Die Nutzungsbedingungen für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH) unter https://www.fdr.uni-hamburg.de/ Eine Englische Version ist unter https://doi.org/10.25592/uhhfdm.10120 verfügbar.
The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis
Creators: name: Der, C. J.
name: Kelly, P.
name: Fields, T. A.
name: Daaka, Y.
name: Booden, M. A.
name: Dewhirst, M. W.
name: Juneja, J.
name: Casey, P. J.
name: Moeller, B. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Although the prognosis for patients with early-stage breast cancer has improved, the therapeutic options for patients with locally advanced and metastatic disease are limited. To improve the treatment of these patients, the molecular mechanisms underlying breast cancer invasion and metastasis must be understood. In this study, we report that signaling through the G12 family of heterotrimeric G proteins (Gα12 and Gα13) promotes breast cancer cell invasion. Moreover, we demonstrate that inhibition of G12 signaling reduces the metastatic dissemination of breast cancer cells in vivo. Finally, we demonstrate that the expression of Gα12 is significantly up-regulated in the earliest stages of breast cancer, implying that amplification of G12 signaling may be an early event in breast cancer progression. Taken together, these observations identify the G12 family proteins as important regulators of breast cancer invasion and suggest that these proteins may be targeted to limit invasion- and metastasis-induced patient morbidity and mortality.
High Cooperativity Cavity QED with Magnons at Microwave Frequencies
Creators: name: Goryachev, Maxim
name: Farr, Warrick G.
name: Creedon, Daniel L.
name: Fan, Yaohui
name: Kostylev, Mikhail
name: Tobar, Michael E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Using a sub-millimetre sized YIG (Yttrium Iron Garnet) sphere mounted in a magnetic field-focusing cavity, we demonstrate an ultra-high cooperativity of $10^5$ between magnon and photon modes at millikelvin temperatures and microwave frequencies. The cavity is designed to act as a magnetic dipole by using a novel multiple-post approach, effectively focusing the cavity magnetic field within the YIG crystal with a filling factor of 3%. Coupling strength (normal-mode splitting) of 2 GHz, (equivalent to 76 cavity linewidths or $0.3$ Hz per spin), is achieved for a bright cavity mode that constitutes about 10% of the photon energy and shows that ultra-strong coupling is possible in spin systems at microwave frequencies. With straight forward optimisations we demonstrate that with that this system has the potential to reach cooperativities of $10^7$, corresponding to a normal mode splitting of 5.2 GHz and a coupling per spin approaching 1 Hz. We also observe a three-mode strong coupling regime between a dark cavity mode and a magnon mode doublet pair, where the photon-magnon and magnon-magnon couplings (normal-mode splittings) are 143 MHz and 12.5 MHz respectively, with HWHM bandwidth of about 0.5 MHz.
description: appears in Phys. Rev. Applied (2014)
Nutzungsbedingungen und Lizenz für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH)
Creators: name: Wörner, Kai
Publisher: name: Universität Hamburg
Year: 2022
Subjects: invenio
fdm
rdm
uhh
terms of use
nutzungsbedingungen

description: Die Nutzungsbedingungen für das Forschungsdatenrepositorium (FDR) der Universität Hamburg (UHH) unter https://www.fdr.uni-hamburg.de/ Eine Englische Version ist unter https://doi.org/10.25592/uhhfdm.10120 verfügbar. Liste der Änderungen: 5.1: Fehler korrigiert, HTML-Version hinzugefügt.
Models of dark matter halos based on statistical mechanics: II. The fermionic King model
Creators: name: Chavanis, Pierre-Henri
name: Lemou, Mohammed
name: Méhats, Florian
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We discuss the nature of phase transitions in the fermionic King model which describes tidally truncated quantum self-gravitating systems. This distribution function takes into account the escape of high energy particles and has a finite mass. On the other hand, the Pauli exclusion principle puts an upper bound on the phase space density of the system and stabilizes it against gravitational collapse. As a result, there exists a statistical equilibrium state for any accessible values of energy and temperature. We plot the caloric curves and investigate the nature of phase transitions as a function of the degeneracy parameter in both microcanonical and canonical ensembles. We consider stable and metastable states and emphasize the importance of the latter for systems with long-range interactions. Phase transitions can take place between a "gaseous" phase unaffected by quantum mechanics and a "condensed" phase dominated by quantum mechanics. The phase diagram exhibits two critical points, one in each ensemble, beyond which the phase transitions disappear. There also exist a region of negative specific heats and a situation of ensemble inequivalence for sufficiently large systems. We apply the fermionic King model to the case of dark matter halos made of massive neutrinos. The gaseous phase describes large halos and the condensed phase describes dwarf halos. Partially degenerate configurations describe intermediate size halos. We argue that large dark matter halos cannot harbor a fermion ball because these nucleus-halo configurations are thermodynamically unstable (saddle points of entropy). Large dark matter halos may rather contain a central black hole resulting from a dynamical instability of relativistic origin occurring during the gravothermal catastrophe.
Profitability and Risk Analysis of the Solar Power Generation Project by the Korea Rural Community Corporation
Creators: name: Kim, Taehoo
name: Kim, Taehoo
Publisher: name: Unknown
Year: 2019
Subjects: subject: Resource /Energy Economics and Policy
subject: solar power generation
subject: simulation
subject: Gaussian Copula

description: The Korean government's energy policy focuses on the spreading of renewable energy. Following this policy, the Korea Rural Community Corporation (KRCC) is promoting the renewable energy generation project with the budget of the Ministry of Agriculture, Food and Rural Affairs (MAFRA). It has plans to use the revenues from power generation as an agricultural infrastructure maintenance cost. This study discusses the effectiveness of the financial investment of the MAFRA by analyzing the profitability and risk of the solar power generation project pursued by KRCC. In order to analyze the profitability and risk, we set the systemic marginal price (SMP) and the price of the renewable energy certificate (REC) as random variables. Then, we perform the simulation with Gaussian Copula to consider the correlations of each random variable. As a result, the average power generation profit of the project is 1.78 billion Won, which implies a high earning rate of 4.91%, considering the total investment cost. In the Value at Risk analysis for the risk of the project, the profit from VaR(1) is 0.46 billion won, and the profit rate is 1.26%, implying that stable profits are generated despite the weak market conditions for the solar power generation.
Newtonian analogue of corresponding spacetime dynamics of rotating black holes: Implication on black hole accretion
Creators: name: Ghosh, Shubhrangshu
name: Sarkar, Tamal
name: Bhadra, Arunava
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Based on the conserved Hamiltonian for a test particle, we have formulated a Newtonian analogue of Kerr spacetime in the `low energy limit of the test particle motion' that, in principle, can be comprehensively used to describe general relativistic (GR) features of Kerr spacetime, however, with less accuracy for high spin. The derived potential, which has an explicit velocity dependence, contains the entire relativistic features of corresponding spacetime including the frame dragging effect, unlike other prevailing pseudo-Newtonian potentials (PNPs) for the Kerr metric where such an effect is either totally missing or introduced in a ad hoc manner. The particle dynamics with this potential precisely reproduce the GR results within a maximum ~ 10 % deviation in energy for a particle orbiting circularly in the vicinity of a rapidly corotating black hole. GR epicyclic frequencies are also well reproduced with the potential, though with a relatively higher percentage of deviation. For counterrotating cases, the obtained potential replicate the GR results with precise accuracy. The Kerr-Newtonian potential also approximates the radius of marginally stable and marginally bound circular orbits with reasonable accuracy for a < 0.7. Importantly, the derived potential can imitate the experimentally tested GR effects like perihelion advancement and bending of light with reasonable accuracy. The formulated Kerr-Newtonian potential thus can be useful to study complex accreting plasma dynamics and its implications around rotating BHs in the Newtonian framework, avoiding GR gas dynamical equations.
description: 18 pages, 10 figures, accepted for the publication in MNRAS