cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Hypersensitivity, immunity and Haemonchus contortus in sheep
Creators: name: Azam, MD Shakif-Ul
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: GIN parasite infections are a major disease problem in small ruminants. Haemonchus contortus is one of the most economically important GIN parasites causing global production losses. Anthelmintic drugs are the commonly used control method for most parasitic infections. However, development of widespread resistance to most current anthelmintics suggests alternative controls are needed. Such strategies may include breeding parasite-resistant sheep and the development of effective vaccines. Currently these approaches are limited due to deficits in our understanding of host-parasite relationships. In this thesis research is described which examined the potential role of cutaneous hypersensitivity reactions to measure and better understand the complexity of the sheep immune response to H. contortus. The first question focused on whether cutaneous hypersensitivity reactions to intradermal injections using distinct antigens (allergens and bacterial antigens) could predict worm resistance or susceptibility in sheep with known genetic worm resistance status. Hypersensitivity reactions were observed to various antigens but their use as a predictive tool for natural resistance in this cohort of sheep appeared limited as there was no correlation with parasitological values. The second aim was to quantify immunological responsiveness to different adjuvants and identify the T1 and T2 pathways contributing to their suitability for use with parasite vaccines. This study found that the putative T2 adjuvant DEAE showed persistence and significant correlations with faecal egg counts (FEC) and various immune parameters. The third aim was to determine whether an efficacious adult sheep vaccine could induce protection in young sheep and determine the immune correlates of the lamb response. This study showed that young vaccinated sheep had significant type 2 parasite specific post-vaccination and post-infection hypersensitivity reactions. A lack of a key immune cell in parasite resistance development, the eosinophil response, was inadequate in comparison to adult vaccine experiments suggesting an inability of young sheep to recruit eosinophils, which may play a role in loss of protective efficacy. In conclusion, these studies have demonstrated that cutaneous hypersensitivity responses with relevant antigens are an effective method of studying the inflammatory response against worm infection. They also allowed analysis of the inflammatory effects of adjuvants but were of limited value as a predictive tool for genetic resistance. Thus, it is suggested that further studies relating dermal hypersensitivity reactions to host-parasite responses may lead to a better understanding of host-parasite interactions and provide useful and easily measured markers to identify specific immune reactions in vaccinated and infected animals.
Additional file 1: Figure S1. of DHEA-induced ovarian hyperfibrosis is mediated by TGF-β signaling pathway
Creators: name: Wang, Daojuan
name: Wang, Wenqing
name: Liang, Qiao
name: He, Xuan
name: Xia, Yanjie
name: Shen, Shanmei
name: Wang, Hongwei
name: Gao, Qian
name: Wang, Yong
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: The serum testosterone (T) and (Estrogen) E2/T levels in control, DHEA and SB431542-treated rats. *p ≤ 0.05, ***p ≤ 0.002. Data are shown as mean ± SEM. Figure S2. The estrous cycle of DHEA-induced PCOS rats disordered. (A) The estrous cycle of the Blank group, Oil group and Oil + DHEA group rats. The abscissa indicates the age of rats. In the proestrus, many nucleated epithelial cells (NEC) were observed. In the estrus, high number of corneous cells (CC) were detected. In the metestrus, visible nucleated epithelial cells, corneous cells and leucocyte (L) were discovered. In the diestrus, a mass of leucocyte can be seen in the field of view. (B) Microscopic examination of vaginal smears stained by toluidine blue. × 200.. D = diestrus; P = proestrus; E = estrus; M = metestrus. Figure S3. The hormone levels after SB431542 treatment. (A) Serum total T levels; (B) E2/T of serum. (DOCX 467 kb)
Additional file 1 of Therapy-induced senescence is a transient drug resistance mechanism in breast cancer
Creators: name: Bajtai, Eszter
name: Kiss, Csaba
name: Bakos, Éva
name: Langó, Tamás
name: Lovrics, Anna
name: Schád, Éva
name: Tisza, Viktória
name: Hegedűs, Károly
name: Fürjes, Péter
name: Szabó, Zoltán
name: Tusnády, Gábor E.
name: Szakács, Gergely
name: Tantos, Ágnes
name: Spisák, Sándor
name: Tóvári, József
name: Füredi, András
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 1
Additional file 1: Figure S1a. of Strategies to control HIV and HCV in methadone maintenance treatment in Guangdong Province, China: a system dynamic modeling study
Creators: name: Zou, Xia
name: Xu, Yong
name: Chen, Wen
name: Xia, Yinghua
name: Liu, Yin
name: Gong, Cheng
name: Ling, Li
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Causal diagram of MMT clinics, participants and detoxification centers. Figure S1b. Causal diagram of HIV/HCV transmission. Figure S1c. HIV testing and treatment systems causal diagram. Figure S1d. Causal diagrams of HIV and HCV testing and treatment systems. Figure S2a. Stock and flow diagram of MMT clinics, participants and detoxification centers. Figure S2b. Stock and flow diagram of HIV and HCV testing and treatment systems. Figure S2c. Stock and flow diagram of HIV transmission system. Figure S2d. Stock and flow diagram of HCV transmission system. Table S1. Parameters of MMT dynamic model. Table S2. System dynamic equations of the MMT system dynamic model. Table S3. Effectiveness of health education, psychological counseling, contingency management, needle exchange program, condom promotion, ART and HCV treatment. (PDF 1349Â kb)
Additional file 3 of Impact of a multi-component implementation strategy to increase outdoor free play opportunities in early childhood education and care (ECEC) services: the get outside get active (GOGA) randomised controlled trial
Creators: name: Yoong, Sze Lin
name: Pearson, Nicole
name: Giles, Luke
name: Lamont, Hannah
name: Wolfenden, Luke
name: Jones, Jannah
name: Lecathelinais, Christophe
name: Naylor, Patti-Jean
name: Okely, Anthony
name: Nathan, Nicole
name: Reilly, Kathryn
name: Lorch, Rebecca
name: Wiggers, John
name: Jackson, Jacklyn
name: Lum, Melanie
name: Gillham, Karen
name: Grady, Alice
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 3
Additional file 1 of Comparison of household socioeconomic status classification methods and effects on risk estimation: lessons from a natural experimental study, Kisumu, Western Kenya
Creators: name: Were, Vincent
name: Foley, Louise
name: Turner-Moss, Eleanor
name: Mogo, Ebele
name: Wadende, Pamela
name: Musuva, Rosemary
name: Obonyo, Charles
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 1: Table S1. Comparison of Kappa reliability analysis between FW, CHV and MCA SES classification. Table S2. Risk estimation of household SES on self-reported hypertension. Table S3. Risk estimation of household SES on self-reported diabetes.
A Ballooned Beta-Logistic Model
Creators: name: Yi, Min
name: Flournoy, Nancy
name: Kpamegan, Eloi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Computational Biology

description: The beta distribution is a simple and flexible model in which responses are naturally confined to the finite interval (0,1). Its parameters can be related to covariates such as dose and gender through a regression model. The ballooned beta-logistic (BBL) model expands the response boundaries from (0,1) to (L,U), where L and U are unknown parameters. Under the BBL model, expected responses follow a logistic function that can be made equal to that of the four-parameter logistic (4PL) model. But the distribution of responses differs from the classical 4PL model that has additive normal errors. In contrast, the BBL model naturally has bounded responses and inhomogenous variance. The asymptotic normality of maximum likelihood estimators (MLEs) is obtained even though the support of this nonregular regression model depends on unknown parameters. We find MLEs converge faster to L and U than extreme values do at the minimum and maximum concentrations. Given enzyme-linked immunosorbent assay data from multiple plates, we study a motivating validation objective, which is to set suitability criteria for estimates of L and U; after this, plates with boundary estimates outside these limits would be considered “reference failures.” We show the BBL model has advantages over the 4PL model. Supplementary materials for this article are available online.
Spin phase regulated spin Josephson supercurrent in topological superconductor
Creators: name: Mao, Yue
name: Sun, Qing-Feng
Publisher: name: arXiv
Year: 2024
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Without applied bias voltage, a superconducting phase difference can drive a charge Josephson supercurrent in a superconductor junction. In analogy, we here theoretically propose a spin phase that intrinsically generates spin Josephson supercurrent, and this spin Josephson effect is studied in a junction of superconducting nanowire (SNW). We show that spin-orbit coupling and magnetic field give rise to spin-triplet superconductivity in the SNW, thus allow the superfluid of both charge and spin. Next we introduce the concept of spin phase that can be generated by controls of spin current, magnetic field or electric field. By the analysis of pairing correlations and Ginzburg-Landau-type theory, it is shown that the spin phase makes spin-up and spin-down $S=1$ Cooper pairs get opposite phases and move oppositely in a Josephson junction, so that a dissipationless pure spin current is induced. We also derive the formula that the spin current is equal to the derivative of Andreev bound state to the spin phase, which is analogous to that of charge Josephson effect. At last, our calculation verifies the existence of spin supercurrent inside the superconducting gap in the topologically nontrivial phase. Our study provides a view on spin Josephson effect and indicates the potential combination of topological superconductivity and spintronics.
description: 9 pages, 3 figures
Group Sequential Survival Trial Design and Monitoring Using the Log-Rank Test
Creators: name: Jianrong Wu
name: Xiaoping Xiong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: For randomized group sequential survival trial designs with unbalanced treatment allocation, the widely used Schoenfeld formula is inaccurate, and the commonly used information time as the ratio of number of events at interim look to the number of events at the end of trial can be biased. In this article, a sample size formula for the two-sample log-rank test under the proportional hazards model is proposed that provides more accurate sample size calculation for unbalanced survival trial designs. Furthermore, a new information time is introduced for the sequential survival trials such that the new information time is more accurate than the traditional information time when the allocation of enrollments is unbalanced in groups. Finally, we demonstrate the monitoring process using the sequential conditional probability ratio test and compare it with two other well-known group sequential procedures. An example is given to illustrate unbalanced survival trial design using available software. Supplementary materials for this article are available online.
Age-dependent differences in DNA damage after in vitro CT exposure
Creators: name: Gomolka, Maria
name: Oestreicher, Ursula
name: Rößler, Ute
name: Samaga, Daniel
name: Endesfelder, David
name: Lang, Peter
name: Neumaier, Klement
name: Belka, Claus
name: Niemeyer, Markus
name: Kiechle, Marion
name: Hasbargen, Uwe
name: Hübener, Christoph
name: Kirlum, Hans-Joachim
name: Kulka, Ulrike
name: Rosenberger, Albert
name: Walsh, Linda
name: Baatout, Sarah
name: Kesminiene, Ausrele
name: Lindholm, Carita
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Purpose: Age dependent radiation sensitivity for DNA damage after in vitro blood exposure by computer tomography (CT) was investigated. Materials and methods: Radiation biomarkers (dicentrics and gammaH2AX) in blood samples of newborns, children under five years and adults after sham exposure (0 mGy), low-dose (41 mGy) and high-dose (978 mGy) in vitro CT exposure were analyzed. Results: Significantly higher levels of dicentric induction were found for the single and combined newborns/children group compared to adults, by a factor of 1.48 (95% CI 1.30–1.68), after exposure to 978 mGy. Although a significant dose response for damage induction and dose-dependent repair was found, the gammaH2AX assay did not show an age-dependent increase in DNA damage in newborns/children compared to adults. This was the case for the gammaH2AX levels after repair time intervals of 30 minutes and 24 hours, after correcting for the underlying background damage. For the low dose of 41 mGy, the power of the dicentric assay was also not sufficient to detect an age-dependent effect in the sample size investigated. Conclusion: A 1.5-fold increased level of dicentric aberrations is detected in newborns and children under five years after 1 Gy radiation exposure.
Additional file 1 of Utilization and costs of epidermal growth factor receptor mutation testing and targeted therapy in Medicare patients with metastatic lung adenocarcinoma
Creators: name: Shen, Chan
name: Holguin, Rolfy A. Perez
name: Schaefer, Eric
name: Zhou, Shouhao
name: Belani, Chandra P.
name: Ma, Patrick C.
name: Reed, Michael F.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1: Appendix Figure 1. Studycohort inclusion and exclusion criteria. STROBEStatement—Checklist of items that should be included in reports of cohort studies.
Relationship Between the Tilt Angle of Sunspot Group and the Properties of the Next Solar Cycle
Creators: name: Gao, P. X.
name: Xu, J. C.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Based on the data from the Kodaikanal and Mount Wilson observatories, we investigate the relationships of the tilt angle of sunspot group (SG), including the mean tilt angle and the tilt-angle scatter, during the declining phase with the parameters of the next solar cycle (SC). The main findings are summarized in the following three points. (1) During the declining phase, the correlation between the mean tilt angle and the tilt-angle scatter is statistically insignificant. (2) Six quantities measured during the declining phase show significant anti-correlations with the strength and amplitude of the next SC, and positive correlations with the duration of the ascending phase of the next SC: the standard deviation of tilt angles, the root-mean-square tilt angle, the mean absolute value of tilt angles, the area-weighted absolute value of tilt angles, the latitude-weighted absolute value of tilt angles, and the area- and latitude-weighted absolute value of tilt angles. (3) The correlations of the mean tilt angle, the area-weighted tilt angle, the latitude-weighted tilt angle, and the area- and latitude- weighted tilt angle during the declining phase with the strength, amplitude, and duration of the ascending phase of the next SC are statistically insignificant. These findings demonstrate that the modulation of parameters of the next SC by the tilt-angle scatter during the declining phase plays a vital role in regulating SC variability.
Additional file 1 of Feasibility and implementation fidelity of a co-designed intervention to promote in-hospital mobility among older medical patients—the WALK-Copenhagen project (WALK-Cph)
Creators: name: Pedersen, Britt Stævnsbo
name: Kirk, Jeanette Wassar
name: Olesen, Maren Kathrine
name: Grønfeldt, Birk Mygind
name: Stefánsdóttir, Nina Thórný
name: Brødsgaard, Rasmus
name: Tjørnhøj-Thomsen, Tine
name: Nilsen, Per
name: Andersen, Ove
name: Bandholm, Thomas
name: Pedersen, Mette Merete
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Additional file 1. The WALK-Cph intervention components.
Phase diagrams and edge-state transitions in graphene with spin-orbit coupling and magnetic and pseudomagnetic fields
Creators: name: Zhuang, Yu-Chen
name: Sun, Qing-Feng
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The quantum Hall (QH) effect, the quantum spin Hall (QSH) effect and the quantum valley Hall (QVH) effect are three peculiar topological insulating phases in graphene. They are characterized by three different types of edge states. These three effects are caused by the external magnetic field, the intrinsic spin-orbit coupling (SOC) and the strain-induced pseudomagnetic field, respectively. Here we theoretically study phase diagrams when these effects coexist and analyze how the edge states evolve between the three. We find the real magnetic field and the pseudomagnetic field will compete above the SOC energy gap while the QSH effect is almost unaffected within the SOC energy gap. The edge states transition from the QH effect or the QVH effect to the QSH effect directly relies on the arrangement of the zeroth Landau levels. Using edge states transitions, we raise a device similar to a spin field effect transistor (spin-FET) and also design a spintronics multiple-way switch.
description: 16 pages, 10 figures
title: OFROM: interview avec unine15b59m
Creators: name: Delafontaine, François
name: Ehinger, Maude
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.ff47g83d.v2#75135446f67bdcecbeb56028f554de9ecfa17101
Age dependent differences in DNA damage after in vitro CT exposure
Creators: name: Gomolka, Maria
name: Oestreicher, Ursula
name: Roessler, Ute
name: Samaga, Daniel
name: Endesfelder, David
name: Lang, Peter
name: Neumaier, Klement
name: Belka, Claus
name: Niemeyer, Markus
name: Kiechle, Marion
name: Hasbargen, Uwe
name: Hübener, Christoph
name: Kirlum, Hans-Joachim
name: Kulka, Ulrike
name: Rosenberger, Albert
name: Walsh, Linda
name: Baatout, Sarah
name: Kesminiene, Ausra
name: Lindholm, Carita
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Purpose: Age dependent radiation sensitivity for DNA damage after in vitro blood exposure by computer tomography (CT) was investigated. Materials and methods: Radiation biomarkers (dicentrics and gammaH2AX) in blood samples of newborns, children under 5 years and adults after sham exposure (0 mGy), low dose (41 mGy) and high dose (978 mGy) in vitro CT exposure were analysed. Results: Significantly higher levels of dicentric induction were found for the single and combined newborns/children group compared to adults, by a factor of 1.48 (95% CI 1.30-1.68), after exposure to 978 mGy. Although a significant dose response for damage induction and dose dependent repair was found, the gammaH2AX assay did not show an age dependent increase in DNA damage in newborns/children compared to adults. This was the case for the gammaH2AX levels after repair time intervals of 30 minutes and 24 hours, after correcting for the underlying background damage. For the low dose of 41 mGy, the power of the dicentric assay was also not sufficient to detect an age dependent effect in the sample size investigated. Conclusions: A 1.5-fold increased level of dicentric aberrations is detected in newborns and children under five years after 1 Gy radiation exposure.
Additional file 2 of Therapy-induced senescence is a transient drug resistance mechanism in breast cancer
Creators: name: Bajtai, Eszter
name: Kiss, Csaba
name: Bakos, Éva
name: Langó, Tamás
name: Lovrics, Anna
name: Schád, Éva
name: Tisza, Viktória
name: Hegedűs, Károly
name: Fürjes, Péter
name: Szabó, Zoltán
name: Tusnády, Gábor E.
name: Szakács, Gergely
name: Tantos, Ágnes
name: Spisák, Sándor
name: Tóvári, József
name: Füredi, András
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 2
Topological phase transition driven by magnetic field in one-dimensional topological superconductor rings
Creators: name: Miao, Cheng-Ming
name: Sun, Qing-Feng
name: Zhang, Ying-Tao
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study the energy spectrum and transport property of a one-dimensional Kitaev quantum ring in a threading magnetic field. It is demonstrated that the magnetic field can effectively induce topological phase transitions for the ring in the topologically nontrivial phase at the zero magnetic field. However, for the ring in the topologically trivial phase at the zero field, there is no topological phase transition, and the energy spectrum of the system is always gapped. The magnetic field can control the appearance and disappearance of Majorana zero-energy states in the Kitaev quantum ring, when one half of the ring is in the topologically nontrivial phase and the other half is in the topologically trivial phase. Furthermore, we calculate the transport properties of the ring connected by two semi-infinite leads. It is found that the resonant peaks of transmission coefficient TQT correspond to the critical points of topological phase transition. In addition, we extend our findings to a more realistic quantum ring adopting a semiconductor nanowire with high spin-orbit coupling, superconducting s-wave pairing, and Zeeman splitting, and prove that our findings are universal.
Additional file 1 of Development of a Temperate Climate-Adapted indica Multi-stress Tolerant Rice Variety by Pyramiding Quantitative Trait Loci
Creators: name: Shin, Na-Hyun
name: Han, Jae-Hyuk
name: Vo, Kieu Thi Xuan
name: Seo, Jeonghwan
name: Navea, Ian Paul
name: Yoo, Soo-Cheul
name: Jeon, Jong-Seong
name: Chin, Joong Hyoun
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Fig. S1. Identification of a unique single nucleotide polymorphism (SNP), Nbs2-Pi9, by multiple sequence alignment of nucleotide-binding sites (Nbss) of the Pi9 gene cloned previously (Qu et al. 2006).
Understanding and Reusing Test Suites Across Database Systems
Creators: name: Zhong, Suyang
name: Rigger, Manuel
Publisher: name: arXiv
Year: 2024
Subjects: subject: Software Engineering (cs.SE)
subject: Databases (cs.DB)
subject: FOS: Computer and information sciences
subject: D.2.5; H.2.4

description: Database Management System (DBMS) developers have implemented extensive test suites to test their DBMSs. For example, the SQLite test suites contain over 92 million lines of code. Despite these extensive efforts, test suites are not systematically reused across DBMSs, leading to wasted effort. Integration is challenging, as test suites use various test case formats and rely on unstandardized test runner features. We present a unified test suite, SQuaLity, in which we integrated test cases from three widely-used DBMSs, SQLite, PostgreSQL, and DuckDB. In addition, we present an empirical study to determine the potential of reusing these systems' test suites. Our results indicate that reusing test suites is challenging: First, test formats and test runner commands vary widely; for example, SQLite has 4 test runner commands, while MySQL has 112 commands with additional features, to, for example, execute file operations or interact with a shell. Second, while some test suites contain mostly standard-compliant statements (e.g., 99% in SQLite), other test suites mostly test non-standardized functionality (e.g., 31% of statements in the PostgreSQL test suite are nonstandardized). Third, test reuse is complicated by various explicit and implicit dependencies, such as the need to set variables and configurations, certain test cases requiring extensions not present by default, and query results depending on specific clients. Despite the above findings, we have identified 3 crashes, 3 hangs, and multiple compatibility issues across four different DBMSs by executing test suites across DBMSs, indicating the benefits of reuse. Overall, this work represents the first step towards test-case reuse in the context of DBMSs, and we hope that it will inspire follow-up work on this important topic.
Etude du comportement des ouvrages de soutènement souples avec prise en compte de la variabilité spatiale du sol
Creators: name: MOKEDDEM, A.
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: On s’intéresse dans le cadre de cette thèse au comportement des ouvrages de soutènement flexibles (les palplanches). Ces ouvrages sont dimensionnés en section droite (en 2D) avec une prise en compte de l’incertitude par le biais des coefficients partiels de sécurité. L’objectif de cette thèse est d’évaluer l’impact de la variabilité spatiale du sol sur le comportement des palplanches à travers une démarche mécano-fiabiliste. Celle-ci est basée d’une part, sur une modélisation des propriétés du sol par des champs aléatoires et d’autre part, sur une modélisation de l’interaction solstructure par un système de plaque et de coefficients de réaction du sol (ce modèle est appelé « MISS-CR-PLQ »). Le calcul tridimensionnel classique et les simulations de Monte Carlo nécessitent un temps de calcul important, d’où l’intérêt de la démarche développée qui a permis d’abord d’optimiser le temps sur la résolution par éléments finis, par le modèle « MISSCR- PLQ », et également à travers la parallélisation des simulations de Monte Carlo. Les premiers résultats exprimés en termes d’indices de fiabilité montrent l’intérêt de la prise en compte de la dimension longitudinale et de la variabilité spatiale des propriétés du sol.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
Second-order topological corner states in zigzag graphene nanoflake with different types of edge magnetic configurations
Creators: name: Miao, Cheng-Ming
name: Sun, Qing-Feng
name: Zhang, Ying-Tao
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the energy spectrum and energy levels of the extended Kane-Mele model with magnetic atoms on their zigzag edges. It is demonstrated that the edges of ferromagnetism or antiferromagnetism are enough to break the time-reversal symmetry and host one-dimensional gapped edge states. Thus, a second-order topological phase transition could happen, which leads to the emergence of topological in-gap zero-dimensional corner states. We also prove that the in-gap corner states are robust against corner defects and magnetic disorder. Our proposal based on the edge antiferromagnetism shows that the high-order topological states can be realized, although the net magnetization of the material is zero. In addition, we discuss the influence of spin magnetization orientation on the degeneracy and energy of in-gap corner states.
description: 9 pages, 8 figures
Additional file 1: of The effect of methamphetamine abuse on dental caries and periodontal diseases in an Eastern China city
Creators: name: Ye, Tao
name: Sun, Dongliang
name: Dong, Guangying
name: Xu, Guangjie
name: Wang, Ligang
name: Du, Jinjin
name: Ren, Pengcheng
name: Yu, Shibin
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Computational Biology

description: Questionnaire-Questionnaire Related with Oral Health-the questionnaire used in the present survey. (DOCX 12 kb)
Building Castles in the Cloud: Architecting Resilient and Scalable Infrastructure
Creators: name: Gundla, Naresh Kumar
Publisher: name: arXiv
Year: 2024
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: In the contemporary world of dynamic digital solutions and services, the significance of effective and stable cloud solutions cannot be overestimated. The cloud adaptation is becoming more popular due to mobile advantages, including flexibility, cheaper costs and scalability. However, creating a fail-proof architecture that can accommodate scale-up and enable high data availability and security is not an easy task. In this paper, a discussion will be made regarding significant measures required in designing contexts inside the cloud environment. It explores the need for replicate servers, fault tolerance, disaster backup and load balancing for high availability. Further, the paper also discusses the optimum strategy for designing cloud infrastructures such as microservices, containerization, and serverless. Based on the literature review, we analyze various approaches that are used to improve cloud reliability and elasticity. The paper also provides a best practice guide for designing a cloud infrastructure for these requirements concerning cases. The results and discussion section outlines the improvement in business continuity and operational efficiency when using the proposed architecture. This paper concludes with recommendations for future studies and the successful application of the elaborated matters.
Containers for Scientific Computing : From laptop to HPC - CSE17
Creators: name: Richardson, Chris
name: Hale, Jack S.
name: Wells, Garth N.
Publisher: name: figshare
Year: 2017
Subjects: subject: Computer Software
subject: FOS: Computer and information sciences

description: Poster from CSE17 showing results with docker and shifter containers
Additional file 1: Table S1. of ASGDB: a specialised genomic resource for interpreting Anopheles sinensis insecticideÂ resistance
Creators: name: Zhou, Dan
name: Xu, Yang
name: Zhang, Cheng
name: Hu, Meng-Xue
name: Huang, Yun
name: Sun, Yan
name: Ma, Lei
name: Shen, Bo
name: Zhu, Chang-Liang
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: The major classes and types of insecticides. (PDF 34Â kb)
Enhancing Financial Question Answering with a Multi-Agent Reflection Framework
Creators: name: Fatemi, Sorouralsadat
name: Hu, Yuheng
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computation and Language (cs.CL)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: While Large Language Models (LLMs) have shown impressive capabilities in numerous Natural Language Processing (NLP) tasks, they still struggle with financial question answering (QA), particularly when numerical reasoning is required. Recently, LLM-based multi-agent frameworks have demonstrated remarkable effectiveness in multi-step reasoning, which is crucial for financial QA tasks as it involves extracting relevant information from tables and text and then performing numerical reasoning on the extracted data to infer answers. In this study, we propose a multi-agent framework incorporating a critic agent that reflects on the reasoning steps and final answers for each question. Additionally, we enhance our system by adding multiple critic agents, each focusing on a specific aspect of the answer. Our results indicate that this framework significantly improves performance compared to single-agent reasoning, with an average performance increase of 15% for the LLaMA3-8B model and 5% for the LLaMA3-70B model. Furthermore, our framework performs on par with, and in some cases surpasses, larger single-agent LLMs such as LLaMA3.1-405B and GPT-4o-mini, though it falls slightly short compared to Claude-3.5 Sonnet. Overall, our framework presents an effective solution to enhance open-source LLMs for financial QA tasks, offering a cost-effective alternative to larger models like Claude-3.5 Sonnet.
description: Accepted by ICAIF 24
Iterative ecological forecasting: Needs, opportunities, and challenges
Creators: name: Dietze, Michael
Publisher: name: figshare
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: NEON Ecological Forecasting workshop report, January 6-8, 2016, USGS Powell Center Ft. Collins, CO
Réalisation d’éco-ciments grâce à la valorisation de cendres volantes de charbon non conventionnelles issues de centrales thermiques Spreader Stoker
Creators: name: SOW, Moustapha
name: TRIBOUT, Christelle
name: CYR, Martin
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: Les centrales thermiques de type Spreader Stoker sont utilisées initialement pour brûler les biomasses comme la bagasse lors de la récolte de la canne à sucre. Cependant, lorsque la saison est terminée, ce type de four peut également être utilisé pour brûler du charbon. L'inconvénient est que les cendres volantes de charbon résultant de ce procédé contiennent beaucoup de particules non brûlées comparées aux cendres volantes de charbon pulvérisées normalisées. Les cendres volantes de Spreader Stoker (CVSS) sont actuellement envoyées en centre l’enfouissement en dépit de leur potentiel de valorisation dans la construction, impliquant donc des enjeux économiques et environnementaux. L'objectif principal de cette étude a donc été d'évaluer le potentiel de fabrication de ciments composés avec CVSS, ainsi que de percevoir le rôle des imbrûlés en caractérisant les CVSS et en étudiant leur comportement dans les matrices cimentaires. L’exploitation numérique d’une base de donnée expérimentale à l’aide de réseaux de neurones artificiels (RNA) a aussi permis d’envisager la prédiction de caractéristiques de mortiers à l’état frais et durci sans avoir à les réaliser.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
Supplementary Material for: Clinical Presentation of Cutaneous Leishmaniasis caused by Leishmania major
Creators: name: Remadi, L.
name: Haouas, N.
name: Chaara, D.
name: Slama, D.
name: Chargui, N.
name: Dabghi, R.
name: Jbeniani, H.
name: Mezhoud, H.
name: Babba, H.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background/Aims: The diagnosis of cutaneous leishmaniasis (CL) is based on the microscopic detection of amastigote, isolation of the parasite, or the detection of Leishmania DNA. Nevertheless, since these techniques are time consuming and not usually available in many endemic countries, the diagnosis remains clinical. Consequently, such disease may be overlooked because of its similarity to other skin diseases. The aim of this study is to describe the clinical polymorphism of CL caused by Leishmaniamajor.Methods: A cross-sectional survey was carried out on 166 patients. Diagnoses were made by both microscopic examination of stained tissue-scraping smears and PCR. The Leishmania species was identified by restriction enzyme analysis of the ribosomal internal transcribed spacer 1 region. The clinical polymorphism was analyzed only for patients with a positive diagnosis for CL and L. major as the identified species. Results and Conclusion: Of the 166 patients, 75 patients fit the inclusion criteria. Twelve different types of CL caused by L. major were defined. The most common type was the ulcero-crusted form followed by the papulonodular form and the impetigenous form. The ulcerated, mucocutaneous, lupoid, and sporotricoid forms were less common. The eczematiform, erysipeloid, verrucous, psoriasiform, and pseudotumoral types were represented by a single case. Zoonotic CL caused by L. major can simulate many other skin diseases, which may lead to a significant spread of this disease and increases in morbidity and drug resistance. This large polymorphism may be the result of a complex association between the genetics of the parasite and the immune response of the host.
Attenuated Clostridium novyias as Cancer antagonist
Creators: name: Macherki M., E.
Publisher: name: figshare
Year: 2017
Subjects: subject: 60501 Bacteriology
subject: FOS: Biological sciences
subject: Cancer

description: A new study by Roberts and colleagues has shown that intratumoural injection of an attenuatedversion of Clostridium novyi bacteria can reduce tumour volume in several preclinical animal modelsas well as in one human.
The cardiovascular effect of incretin-based therapies among type 2 diabetes: a systematic review and network meta-analysis
Creators: name: Wu, Shanshan
name: Cipriani, Andrea
name: Yang, Zhirong
name: Yang, Jun
name: Cai, Ting
name: Xu, Yang
name: Quan, Xiaochi
name: Zhang, Yuan
name: Chai, Sanbao
name: Sun, Feng
name: Zhan, Siyan
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Science Policy

description: Objective: To evaluate the comparative cardiovascular safety of incretin-based therapies in patients with type 2 diabetes mellitus (T2DM). Methods: Medline, Embase, the Cochrane Library and www.clinicaltrials.gov were searched for randomized controlled trials (RCTs) with duration≥12 weeks. Network meta-analysis was performed, followed by subgroup analysis and meta-regression. The Grading of Recommendations Assessment, Development and Evaluation system was used to assess the quality of evidence. The outcome of interest was a composite of cardiovascular death, myocardial infarction, stroke and heart failure. Odds ratio (OR) with 95% confidence interval (CI) was calculated as the measure of effect size. Results: 281 RCTs (76.9% double-blinded) with 180,000 patients were included, comparing incretin-based therapies with other six classes of anti-diabetic drugs or placebo. A statistically significant reduction in the risk of cardiovascular events was found in favour of GLP-1RAs when compared with placebo (OR 0.89, 95%CI: 0.80–0.99) and sulfonylurea (OR 0.76, 95%CI: 0.59–0.99), whereas DPP-4 inhibitors showed a neutral effect compared with placebo (OR 0.92, 95%CI: 0.83–1.01). Conclusions: Incretin-based therapies show similar cardiovascular risk in comparison with metformin, insulin, thiazolidinediones, alpha-glucosidase inhibitor and sodium-glucose co-transporter 2. GLP-1RA could decrease the risk compared with sulfonylurea or placebo, while DPP-4I appears to have neutral effect on cardiovascular risk.
Effect of oxygen and heating on aromas of pummelo (Citrus maxima) essential oil
Creators: name: Sun, Hao
name: Ni, Hui
name: Chen, Feng
name: Jiang, Zedong
name: Huang, Gaoling
name: Yang, Yuanfan
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Objective: To investigate effects of oxygen and heating on aromas and volatile components of pummelo essential oil (PEO). Method: The PEOs were analyzed by sensory evaluation, gas chromatography coupled with mass spectrometry (GC-MS), GC-olfactometry (GC-O) and sensory reconstruction analysis. Results: The PEO co-treated by oxygen and heating exhibited significant differences in both aromas and volatile compositions from those of the fresh, the nitrogen-protected, the heated and the oxygen-exposed PEOs. The strong sweet and floral notes of the oxygen and heating co-treated PEO were attributed to high concentration of limonene oxides; the strong minty note was resulted from the increase of L-carvone. Conclusion: The results indicate that limonene oxides and L-carvone could significantly change the aroma of PEO co-treatment by oxygen and heating, providing valuable information for the production and storage of aromatic products of PEO.
Engineering topologically protected zero-dimensional interface end states in antiferromagnetic heterojunction graphene nanoflakes
Creators: name: Miao, Cheng-Ming
name: Wan, Yu-Hao
name: Sun, Qing-Feng
name: Zhang, Ying-Tao
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the energy band structure and energy levels of a heterojunction composed of two antiferromagnetic graphene nanoflakes with opposite in-plane antiferromagnetic orderings, in which the modified Kane-Mele model is employed. Before forming an antiferromagnetic graphene heterojunction, the energy gap of helical edge states in each isolated graphene nanoflake are opened by the antiferromagnetic ordering and there is no the in-gap corner state. We find that when two opposite antiferromagnetic graphenes are coupled to form a heterojunction nanoflake, topologically protected zero-dimensional in-gap states can be induced. In addition, we demonstrate that the in-gap states locate at the end of the interface and are robust against magnetic disorder, Anderson disorder, and interfacial magnetic defects. The position and number of the in-gap interface end states in the heterojunction sample can be precise quantum controlled.
description: 13 pages,12 figures
title: OFROM: interview avec unine15b58m
Creators: name: Delafontaine, François
name: Ehinger, Maude
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.83b20f3b.v2#a3e3c36c4962f7f17b29bab15ebb5a0eeb6081c2
Étude expérimentale et numérique des matériaux cimentaires sous sollicitation hydro-mécanique
Creators: name: SOLEILHET, François
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: Les matériaux cimentaires et notamment le béton sont parmi les matériaux principalement utilisés dans la construction des ouvrages de génie civil. Les enjeux de durabilité incitent à prédire leurs propriétés à long terme, étroitement liées aux risques de fissuration. Néanmoins, l’histoire de chargement hydrique génère des contraintes internes impactant ses propriétés tant en terme de résistance que de module de Young ou bien encore d’énergie dissipée. Dans le cadre de cette communication, une étude expérimentale sur l’effet de la dessiccation sur les propriétés mécaniques du béton est menée, sous des conditions hydriques variées. En concordance avec les résultats observés, cet effet est inclus dans un processus de simulation prenant comme étape la détermination de l’état hydrique du matériau, la modélisation des déformations de retrait induites et se terminant par le calcul mécanique. Ceci permettra de prédire l’évolution des caractéristiques mécaniques, la fissuration induite et les propriétés de transports résiduelles du béton dans le temps.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes