cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Measuring Polarized Emission in Clusters in the CMB S4 Era
Creators: name: Louis, Thibaut
name: Bunn, Emory F.
name: Wandelt, Benjamin
name: Silk, Joseph
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The next generation of CMB experiments (CMB Stage-4) will produce a Sunyaev-Zel'dovich (SZ) cluster catalog containing $\sim10^{5}$ objects, two orders of magnitudes more than currently available. In this paper, we discuss the detectability of the polarized signal generated by scattering of the CMB quadrupole on the cluster electron gas using this catalog. We discuss the possibility of using this signal to measure the relationship between cluster optical depth and mass. We find that the area of observation of S4 maximizes the signal-to-noise (S/N) on the polarized signal but that this S/N is extremely small for an individual cluster, of order 0.5% for a typical cluster in our catalog, the main source of noise being the residual primordial E-mode signal. However, we find that the signal could be detected using the full cluster catalog and that the significance of the result will increase linearly with the size of the CMB S4 telescope mirror.
description: 10 pages, 7 figures, version matching the one published in PRD
Additional file 3 of Metagenomics reveals global-scale contrasts in nitrogen cycling and cyanobacterial light-harvesting mechanisms in glacier cryoconite
Creators: name: Murakami, Takumi
name: Takeuchi, Nozomu
name: Mori, Hiroshi
name: Hirose, Yuu
name: Edwards, Arwyn
name: Irvine-Fynn, Tristram
name: Li, Zhongqin
name: Ishii, Satoshi
name: Segawa, Takahiro
Publisher: name: figshare
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 2: Figure S1. Bacterial class composition based on 16S rRNA read abundance. Figure S2. Hierarchical clustering of cryoconite samples based on the abundance of 16S rRNA genes (upper) and KEGG-annotated genes (lower). Figure S3. Phylogenetic positions of 16S rRNA gene phylotypes of Cyanobacteria. Figure S4. Read abundance of the genes responsible for CO2 fixation. Figure S5. Read abundance of the genes responsible for aerobic respiration. Figure S6. Read abundance of the genes involved in the fermentation. Figure S7. Read abundance of the genes encoding the subunit of hydrogenases. Figure S8. Read abundance of the genes responsible for photosystems. Figure S9. Read abundance of the genes involved in the psychrotolerance. Figure S10. Composition of cyanobacterial lineages based on the read abundance of the metagenome-assembled genomes (MAGs).
Scrapbooks Sent to a Tank Commander in North Africa
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: The contributor shared that the scrapbooks she had brought for digitisation had been made by her mother, Gwyneth Atwood, for her husband, Cecil Atwood, who was based in North Africa during the Second World War. Cecil was living in Sandhurst when he was commissioned to join Army in 1939, and he rose to the rank of Major as a tank commander. After being demobilised, Cecil returned to London to look after tanks. The contributor noted that her mother worked in hospitals during the Second World War. The contributor highlighted that neither of her parents enjoyed speaking about the war because they did not want to recall their memories from war.
Photospheric properties and fundamental parameters of M dwarfs
Creators: name: Rajpurohit, A. S.
name: Allard, F.
name: Teixeira, G. D. C.
name: Homeier, D.
name: Rajpurohit, S.
name: Mousis, O.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: M dwarfs are an important source of information when studying and probing the lower end of the Hertzsprung-Russell (HR) diagram, down to the hydrogen-burning limit. Being the most numerous and oldest stars in the galaxy, they carry fundamental information on its chemical history. The presence of molecules in their atmospheres, along with various condensed species, complicates our understanding of their physical properties and thus makes the determination of their fundamental stellar parameters more challenging and difficult. The aim of this study is to perform a detailed spectroscopic analysis of the high-resolution H-band spectra of M dwarfs in order to determine their fundamental stellar parameters and to validate atmospheric models. The present study will also help us to understand various processes, including dust formation and depletion of metals onto dust grains in M dwarf atmospheres. The high spectral resolution also provides a unique opportunity to constrain other chemical and physical processes that occur in a cool atmosphere The high-resolution APOGEE spectra of M dwarfs, covering the entire H-band, provide a unique opportunity to measure their fundamental parameters. We have performed a detailed spectral synthesis by comparing these high-resolution H-band spectra to that of the most recent BT-settl model and have obtained fundamental parameters such as effective temperature, surface gravity, and metallicity (Teff, log g and [Fe/H]) respectively.
description: 15 pages, 10 figures, accepted for publication in A&A
Mechanical and morphological bond line properties of silver birch wood pretreated by aqueous extraction
Creators: name: Engelhardt, Max
name: Böger, Thomas
name: Gigl, Michael
name: Meng, Chen
name: Richter, Klaus
name: Sánchez-Ferrer, Antoni
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology

description: While bonding for structural applications in Europe was limited to only a few softwood species in the past, forest alterations toward more climate stability will increase the diversity of tree species. This requires an understanding of typal wood-adhesive interactions. To help facilitate birch wood bonding, its cold-water soluble extractives and their effects on mechanical performance and bond line morphology were studied using water-borne melamine-urea-formaldehyde (MUF) and hydrophobic solvent-free polyurethane (PUR) adhesives. Extractives classes were identified via mass spectrometry and their concentration and extraction kinetics were evaluated. The analysis revealed that the mechanical properties of the bond line were essentially unaffected by extraction when using the hydrophobic PUR adhesive. Increased degrees of extraction resulted in reduced MUF penetration, and slightly thicker bond lines, however, the mechanical results indicate improved performance, indicating fewer defects in the cured adhesive network.
A regularity criterion for the Navier-Stokes equation involving only the middle eigenvalue of the strain tensor
Creators: name: Miller, Evan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35, 76

description: This manuscript derives an evolution equation for the symmetric part of the gradient of the velocity (the strain tensor) in the incompressible Navier-Stokes equation on $\mathbb{R}^3$, and proves the existence of $L^2$ mild solutions to this equation. We use this equation to obtain a simplified identity for the growth of enstrophy for mild solutions that depends only on the strain tensor, not on the nonlocal interaction of the strain tensor with the vorticity. The resulting identity allows us to prove a new family of scale-critical, necessary and sufficient conditions for the blow-up of a solution at some finite time $T_{max}
description: Arch Rational Mech Anal (2019)
Species composition of the genus Scombrops (Teleostei, Scombropidae) in the waters around the Japanese Archipelago: detection of a cryptic species
Creators: name: Itoi, Shiro
name: Mochizuki, Yukako
name: Tanaka, Minori
name: Oyama, Hikaru
name: Tadasuke Tsunashima
name: Yamada, Riko
name: Shishido, Hirotoshi
name: Masuda, Yasuji
name: Nakai, Shizuko
name: Takai, Noriyuki
name: Fukushima, Hideto
name: Abe, Koko
name: Kojima, Takahito
name: Sugita, Haruo
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Current literature states that family Scombropidae consists of a single genus Scombrops comprising three species worldwide, with two of them, Scombrops boops and Scombrops gilberti, distributed in the waters around the Japanese Archipelago. Although these two scombropids are commercially important species, little is known about the ecology of these fishes. It is difficult to discriminate between these two species based on external characteristics because of their morphological similarity. Here, we report two different morphotypes characterized by the relative growth between the otolith size and the standard length (SL) of the scombropid specimens caught in southern waters off Kyushu Island, Japan, and show the genetic relationship between the morphotypes by means of phylogenetic analyses using complete DNA sequences of the cytochrome b gene. The relationship between otolith weight and SL was significantly different between specimens 550 mm SL. Phylogenetic analysis demonstrated that the sequences from these scombropid specimens formed three clades: two corresponded to S. boops and S. gilberti, while the third did not correspond to any sequence recorded in databases, suggesting that these specimens are undescribed scombropid species. Almost all the specimens with SL n = 76) were identified as S. boops, and only nine as S. gilberti. On the other hand, almost all the specimens with SL > 550 mm (n = 41) fell in the unidentified group except for four specimens, whose sequences were identical to that of S. boops.
CURSO CONEXÃO COM O PROJETO POLÍTICO PEDAGÓGICO
Creators: name: Nunes, Kezia Rodrigues
Publisher: name: Zenodo
Year: 2023

description: Trata-se de um produto técnico-tecnológico vinculado à área da Educação, materializado por meio de um curso de formação de profissionais da Educação, com carga horária de 45 horas, ofertado pela Universidade Federal do Espírito Santo (Ufes). O Curso de Extensão “Conexão com o Projeto Político Pedagógico” é a versão MOOC de outras versões realizadas de modo presencial e semipresencial, coordenada por mim e desenvolvida em parceria com a Pró-reitoria de Extensão (Proex) da Ufes, com o nosso grupo de pesquisa e com as escolas parceiras, no período compreendido entre os anos 2013 a 2022. Assim, esta versão sistematiza as principais contribuições e revisões das versões anteriores para o formato MOOC, ou seja, para um Curso Online, Aberto e Massivo (do inglês: Massive Open Online Courses).
Continuous phase-space representations for finite-dimensional quantum states and their tomography
Creators: name: Koczor, Bálint
name: Zeier, Robert
name: Glaser, Steffen J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Continuous phase spaces have become a powerful tool for describing, analyzing, and tomographically reconstructing quantum states in quantum optics and beyond. A plethora of these phase-space techniques are known, however a thorough understanding of their relations was still lacking for finite-dimensional quantum states. We present a unified approach to continuous phase-space representations which highlights their relations and tomography. The infinite-dimensional case from quantum optics is then recovered in the large-spin limit.
description: 15 pages, 9 figures, v4: extended tomography analysis, added references and figures
Aqueous ethanol fractionation of softwood and hardwood kraft lignins: Impact on purity and properties
Creators: name: Beaudoin, Daniel
name: Langis-Barsetti, Sophie
name: Gagné, Alain
name: Palus, Ernest
name: Inwood, John
name: Konduri, Mohan K. R.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: Plant Biology

description: Industrial kraft lignins are mixtures of macromolecular components variable in both structure and composition. To maximize their value in commercial applications, they often need to be homogenized and purified. Several fractionation methods have been reported to improve the properties of kraft lignins, but these reports have been mostly limited to kraft lignins of single origins. In this study, the physicochemical properties of fractions from four industrial kraft lignins were compared. Fractionation was performed on both softwood and hardwood lignins by partial dissolution in aqueous ethanol followed by precipitation with water. The yields of each fraction varied greatly between the lignins, with differences reaching up to 35% for a single fraction. All fractions were characterized which showed that fractions having remarkably similar properties and compositions can be obtained from different lignins. Organic and inorganic impurities were found to concentrate in specific fractions which allowed the isolation of highly purified fractions of kraft lignin. These results highlight the importance of matching individual kraft lignins with suitable applications.
Narrow exotic tetraquark mesons in large-$N_c$ QCD
Creators: name: Lucha, Wolfgang
name: Melikhov, Dmitri
name: Sazdjian, Hagop
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Discussing four-point Green functions of bilinear quark currents in large-$N_c$ QCD, we formulate rigorous criteria for selecting diagrams appropriate for the analysis of potential tetraquark poles. We find that both flavor-exotic and cryptoexotic (i.e., flavor-nonexotic) tetraquarks, if such poles exist, have a width of order $O(1/N_c^2)$, so they are parametrically narrower compared to the ordinary $\bar qq$ mesons, which have a width of order $O(1/N_c)$. Moreover, for flavor-exotic states, the consistency of the large-$N_c$ behavior of "direct" and "recombination" Green functions requires two narrow flavor-exotic states, each coupling dominantly to one specific meson-meson channel.
description: 5 pages, version to appear in PRD, minor text modifications, conclusions remain unchanged
Phase Offsets and the Energy Budgets of Hot Jupiters
Creators: name: Schwartz, Joel C.
name: Kashner, Zane
name: Jovmir, Diana
name: Cowan, Nicolas B.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Thermal phase curves of short-period planets on circular orbits provide joint constraints on the fraction of incoming energy that is reflected (Bond albedo) and the fraction of absorbed energy radiated by the night hemisphere (heat recirculation efficiency). Many empirical studies of hot Jupiters have implicitly assumed that the dayside is the hottest hemisphere and the nightside is the coldest hemisphere. For a given eclipse depth and phase amplitude, an orbital lag between a planet's peak brightness and its eclipse---a phase offset---implies that planet's nightside emits greater flux. To quantify how phase offsets impact the energy budgets of short-period planets, we compile all infrared observations of the nine planets with multi-band eclipse depths and phase curves. Accounting for phase offsets shifts planets to lower Bond albedo and greater day--night heat transport, usually by $\lesssim 1σ$. For WASP-12b, the published phase variations have been analyzed in two different ways, and the inferred energy budget depends sensitively on which analysis one adopts.\ Our fiducial scenario supports a Bond albedo of $0.27^{+0.12}_{-0.13}$, significantly higher than the published optical geometric albedo, and a recirculation efficiency of $0.03^{+0.07}_{-0.02}$, following the trend of larger day--night temperature contrast with greater stellar irradiation. If instead we adopt the alternative analysis, then WASP-12b has a Bond albedo consistent with zero and a much higher recirculation efficiency. To definitively determine the energy budget of WASP-12b, new observational analyses will be necessary.
description: 11 pages, 6 figures, 2 tables; Accepted in ApJ. Minor corrections to text/references. (Improved treatment of stellar brightness temperatures and systematic uncertainties; better discussion of WASP-12b; updated Figures 2, 3, and 5, and fit parameters in Tables 1 and 2)
Phylogeographic pattern of Liza affinis populations in Chinese coastal waters: estimation of larval dispersal potential
Creators: name: Liu, Lu
name: Liqin Liu
name: Tianxiang Gao
name: Song, Na
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: To examine phylogeographic pattern of Liza affinis populations in Chinese coastal waters, eight geographic populations were collected and analyzed using sequence analysis based on the first hypervariable region of mitochondrial control region. A total of 117 haplotypes from eight populations were obtained from 223 individuals and 22 of them were shared among different populations. High values of haplotype diversity and nucleotide diversity were observed for eight populations. The topology of the NJ tree was shallow, and there were no significant genealogical branches or clusters corresponding to sampling localities. The values of pairwise Fst ranged from −0.009 to 0.171 and most of them were not statistically significant after sequential Bonferroni correction. The results of LAMARC also indicated no significant population genetic structure in L. affinis along the Chinese coast. The demographic history of Liza affinis examined by neutrality tests and mismatch distribution analysis suggested a population expansion event dating back to late Pleistocene. The potential larval dispersal ability coupled with the present ocean currents and the late Pleistocene environment should be responsible for the present phylogeographic pattern of Liza affinis.
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 269
Creators: name: de la Côte d'Or, Archives départementales
name: CG21/F.PETOT/2012
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 269, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 269, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Tunable dimensional crossover and magnetocrystalline anisotropy in Fe$_2$P-based alloys
Creators: name: Zhuravlev, I. A.
name: Antropov, V. P.
name: Vishina, A.
name: van Schilfgaarde, M.
name: Belashchenko, K. D.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Electronic structure calculations are used to examine the magnetic properties of Fe$_2$P-based alloys and the mechanisms through which the Curie temperature and magnetocrystalline anisotropy can be optimized for specific applications. It is found that at elevated temperatures the magnetic interaction in pure Fe$_2$P develops a pronounced two-dimensional character due to the suppression of the magnetization in one of the sublattices, but the interlayer coupling is very sensitive to band filling and structural distortions. This feature suggests a natural explanation of the observed sharp enhancement of the Curie temperature by alloying with multiple elements, such as Co, Ni, Si, and B. The magnetocrystalline anisotropy is also tunable by electron doping, reaching a maximum near the electron count of pure Fe$_2$P. These findings enable the optimization of the alloy content, suggesting co-alloying of Fe$_2$P with Co (or Ni) and Si as a strategy for maximizing the magnetocrystalline anisotropy at and above room temperature.
description: 5 pages, 7 figures, revised and corrected
AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner
Creators: name: Huang, Wei
name: Li, Na
name: Zhang, Yi
name: Wang, Xu
name: Yin, Miao
name: Lei, Qun-Ying
Publisher: name: Taylor & Francis
Year: 2021
Subjects: Biochemistry
Space Science
Molecular Biology
Neuroscience
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Cancer
Science Policy
Computational Biology

description: S-adenosyl-l-homocysteine (SAH), an amino acid derivative, is a key intermediate metabolite in methionine metabolism, which is normally considered as a harmful by-product and hydrolyzed quickly once formed. AHCY (adenosylhomocysteinase) converts SAH into homocysteine and adenosine. There are two other members in the AHCY family, AHCYL1 (adenosylhomocysteinase like 1) and AHCYL2 (adenosylhomocysteinase like 2). Here we define AHCYL1 function as a SAH sensor to inhibit macroautophagy/autophagy through PIK3C3. The C terminus of AHCYL1 interacts with SAH specifically and the interaction with SAH promotes the binding of the N terminus to the catalytic domain of PIK3C3, resulting in inhibition of PIK3C3. More importantly, this observation was further validated in vivo, indicating that SAH functions as a signaling molecule. Our study uncovers a new axis of SAH-AHCYL1-PIK3C3, which senses the intracellular level of SAH to inhibit autophagy in an MTORC1-independent manner. Abbreviations: ADOX: adenosine dialdehyde; AHCY: adenosylhomocysteinase; AHCYL1: adenosylhomocysteinase like 1; cLEU: cycloleucine; PIK3C3: phosphatidylinositol 3-kinase catalytic subunit type 3; PtdIns3P: phosphatidylinositol-3-phosphate; SAH: S-adenosyl-l-homocysteine; SAM: S-adenosyl-l-methionine.
Photos from RAF Air Gunner and ATS Worker at Bletchley Park
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: The contributor advised that his father, Norman Ernest Wade, was a Royal Air Force Wireless Operator Air Gunner in the India Coastal Command who became an Officer and remained in the RAF after the Second World War. Prior to the war, Norman Ernest Wade was a railway worker in London at 16 years of age in 1936. In 1939, Norman joined the RAF and trained as an air gunner in Scotland. The contributor shared a story in which Norman shot at a blue whale from a submarine. The contributor noted that Norman was relocated to Calcutta pre-partition, and several photos document Norman's daily life at this time. It was highlighted that Norman was known for this athleticism, and he had stated that he did not see much action during the Second World War. The contributor's mother, Marjorie Ins Nidd, became engaged and married to his father in 1946. The contributor was also born in 1946. Marjorie worked for the Auxiliary Territorial Service and was stationed at Bletchley Park during the Second World War. The contributor explained that Marjorie made very strong connections with friends at her post, and she maintained these relationships until her death, although she never spoke about her experience with the ATS. The contributor highlighted a photo of his mother at her radio station with a dog she adopted at Harrogate. The contributor's parents were reunited after the war had ended.
Relating 't Hooft Anomalies of 4d Pure Yang-Mills and 2d $\mathbb{CP}^{N-1}$ Model
Creators: name: Yamazaki, Masahito
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: It has recently been shown that a center-twisted compactification of the four-dimensional pure $SU(N)$ Yang-Mills theory on a three-torus gives rise to the two-dimensional $\mathbb{CP}^{N-1}$-model on a circle with a flavor-twisted boundary condition. We verify the consistency of this statement non-perturbatively at theta angle $θ=π$, in terms of the mixed 't Hooft anomalies for flavor symmetries and the time-reversal symmetry. This provides further support for the approach to the confinement of four-dimensional Yang-Mills theory from the two-dimensional $\mathbb{CP}^{N-1}$-model.
description: 6 pages; v3: published version
Additional file 1 of A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates
Creators: name: Al Adhami, Hala
name: Bardet, Anaïs Flore
name: Dumas, Michael
name: Cleroux, Elouan
name: Guibert, Sylvain
name: Fauque, Patricia
name: Acloque, Hervé
name: Weber, Michael
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology

description: Additional file 1: Figs. S1-S7. Figure S1: Expression of DNMT genes and additional analysis of vertebrate methylomes in muscle and sperm. Figure S2: Analysis of DNA methylation in CG-rich regions in vertebrate muscle datasets. Figure S3: Analysis of DNA methylation in CG-rich regions of vertebrate gametes. Figure S4: Correlation between gene body methylation and gene expression in vertebrates. Figure S5: Promoter classification and analysis of promoter DNA methylation in vertebrates. Figure S6: Genome-wide DNA methylation and gene expression patterns upon 5azadC treatment in dermal fibroblasts. Figure S7: Reactivation of transposable elements by 5azadC treatment in vertebrates.
title: AN, Registre des écrous du Châtelet, Y5266, f. p1000734
Creators: name: Claustre, Julie
name: Nationales, Archives
name: ArchivesNationales/J.CLAUSTRE/H.REGAZZI/2020
name: Archives Nationales
name: Claustre, Julie
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Châtelet
subject: registre
subject: LaMOP

description: Registre des écrous du Châtelet, Archives Nationales, Y5266. Numérisation en mode image.
description: Bibliographic citation: Archives Nationales, Registre des écrous du Châtelet, Y5266, f. p1000734
Ensemble-Based Computational Enzyme Design: Methods and Applications
Creators: name: Rakotoharisoa, Rojo
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2024
Subjects: Computational enzyme design

description: Designing artificial enzymes to meet the increasing demand for industrial applications holds immense societal significance. However, despite successes in de novo enzyme design methodologies, artificial enzymes exhibit low catalytic efficiency compared to natural ones. In this thesis, we studied structural changes occurring during the evolution of a low-activity de novo Kemp eliminase HG3 (k_cat/K_M 146 M⁻¹s⁻¹). We observed a rigidification of catalytic residues, a better active site pre-organization and a wider active site entrance. Using backbone ensembles from ensemble refinement (ER) of crystallographic data of HG3, our ensemble-based enzyme design method allowed a high prediction accuracy of HG4, a highly efficient enzyme we engineered (k_cat/K_M 103,000 M⁻¹s⁻¹) containing key first and second-shell mutations found during evolution. Building upon these findings, we established a benchmark of our ensemble-based method using backbone ensembles from various methods obtained from a weakly active Kemp Eliminase, HG3. Our results showed that ensembles derived from PertMin, a method we previously developed, and ER accurately predicted the conformation of its optimized variant, HG4. This benchmark served as a guide for improving the catalytic efficiency of HG3 and KE70 (k_cat/K_M 57 M⁻¹ s⁻¹). Designed sequences displayed catalytic efficiency that improved by 100-250-fold, comparable to screening thousands of variants from rounds of directed evolution. Finally, we benchmarked our ensemble-based design method for predicting to stabilize the multiple transition states of the reaction catalyzed by BH32.12, an evolved variant of BH32 catalyzing the Morita-Baylis-Hillman reaction. Our research advances the field of enzyme design by combining evolutionary insights with computational approaches, leading to the creation of highly efficient artificial enzymes for various applications.
MIAMI
Creators: name: Morrissey, Eimear
name: Molloy, Gerry
name: Murphy, Patrick
name: Murphy, Andrew
name: O’Grady, Louise
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: Hypertension is one of the most important risk factors for stroke and heart disease. Recent international guidelines have stated that 'poor adherence to treatment – in addition to physician inertia - is the most important cause of poor blood pressure control'. The MaxImising Adherence, Minimising Inertia (MIAMI) intervention, which has been developed using a systematic, theoretical, user-centred approach, aims to support general practitioners (GPs) and people with hypertension to maximise medication use, through the facilitation of adequate information exchange within consultations about long-term antihypertensive medication use and adherence skill development. The aim of the MIAMI pilot cluster randomised controlled trial (RCT) is to gather and analyse feasibility data to allow us to (1) refine the intervention, and (2) determine the feasibility of a definitive RCT.
A novel technique for determining luminosity in electron-scattering/positron-scattering experiments from multi-interaction events
Creators: name: Schmidt, A.
name: O'Connor, C.
name: Bernauer, J. C.
name: Milner, R.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Nuclear Experiment (nucl-ex)
subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: The OLYMPUS experiment measured the cross-section ratio of positron-proton elastic scattering relative to electron-proton elastic scattering to look for evidence of hard two-photon exchange. To make this measurement, the experiment alternated between electron beam and positron beam running modes, with the relative integrated luminosities of the two running modes providing the crucial normalization. For this reason, OLYMPUS had several redundant luminosity monitoring systems, including a pair of electromagnetic calorimeters positioned downstream from the target to detect symmetric Mø ller and Bhabha scattering from atomic electrons in the hydrogen gas target. Though this system was designed to monitor the rate of events with single Mø ller/Bhabha interactions, we found that a more accurate determination of relative luminosity could be made by additionally considering the rate of events with both a Mø ller/Bhabha interaction and a concurrent elastic $ep$ interaction. This method was improved by small corrections for the variance of the current within bunches in the storage ring and for the probability of three interactions occurring within a bunch. After accounting for systematic effects, we estimate that the method is accurate in determining the relative luminosity to within 0.36\%. This precise technique can be employed in future electron-proton and positron-proton scattering experiments to monitor relative luminosity between different running modes.
Descripción de dos nuevas especies y nuevos registros del género Epilachna Chevrolat (Coleoptera: Coccinellidae) en el Perú / Description of two new species and new records of the genus Epilachna Chevrolat (Coleoptera: Coccinellidae) in Peru
Creators: name: Navarrete, Abdhiel Arnaldo Bustamante
name: Ramos, Anahi Oroz
name: Araseli Elme Tumpay
name: Marquina-Montesinos, Edgar
name: Landa, Erick Yabar
Publisher: name: figshare
Year: 2018
Subjects: subject: Zoology
subject: FOS: Biological sciences
subject: 60899 Zoology not elsewhere classified

description: Epilachna lucianae n. sp. y Epilachna matei n.sp. son descritas en base a ejemplares colectados en las regiones peruanas de Huánuco y Cusco; se proveen además nuevos registros de tres especies del género Epilachna Chevrolat para el Perú / Epilachna lucianae n. sp. and Epilachna matei n. sp. are described using specimens collected in the Peruvian regions of Huanuco and Cusco; new records are also provided for some species of the genus Epilachna Chevrolat for Peru.
title: COMPUTATIONAL CRYPTOGRAPHY
title: Υπολογιστική κρυπτογραφία
Creators: name: Pagourtzis, Aristeidis
name: Zachos, Efstathios
Publisher: name: Kallipos, Open Academic Editions
Year: 2016
Subjects: ΚΡΥΠΤΟΓΡΑΦΙΑ
ΥΠΟΛΟΓΙΣΤΙΚΗ ΠΟΛΥΠΛΟΚΟΤΗΤΑ
ΥΠΟΛΟΓΙΣΤΙΚΗ ΘΕΩΡΙΑ ΑΡΙΘΜΩΝ
ΣΥΜΜΕΤΡΙΚΗ ΚΡΥΠΤΟΓΡΑΦΙΑ
ΚΡΥΠΤΟΓΡΑΦΙΑ ΔΗΜΟΣΙΟΥ ΚΛΕΙΔΙΟΥ
ΚΡΥΠΤΟΓΡΑΦΙΚΑ ΠΡΩΤΟΚΟΛΛΑ
ΑΣΦΑΛΕΙΑ ΠΛΗΡΟΦΟΡΙΩΝ
ΑΣΦΑΛΕΙΑ ΔΙΚΤΥΩΝ
Cryptography
Computational Complexity
Computational Number Theory
Symmetric Cryptography
Public Key Cryptography
Cryptographic Protocols
Information Security
Network Security

description: Το βιβλίο αποσκοπεί να εισαγάγει τον αναγνώστη στις θεμελιώδεις έννοιες και τεχνικές της κρυπτογραφίας, με έμφαση στην αλγοριθμική και υπολογιστική διάστασή τους. Τα περιεχόμενα συνοπτικά:
- Εισαγωγή σε βασικές έννοιες αλγορίθμων και πολυπλοκότητας: ανάλυση αλγορίθμων, αποδοτικότητα, πολυωνυμικός χρόνος, πιθανοτικοί αλγόριθμοι, κλάσεις πολυπλοκότητας.
- Στοιχεία θεωρίας αριθμών και θεωρίας ομάδων: αριθμητική modulo, ομάδες, δακτύλιοι, σώματα, Κινέζικο Θεώρημα Υπολοίπων, Θεωρήματα Fermat, Euler, Lagrange, πρωταρχικές ρίζες, συνάρτηση φ του Euler, τετραγωνικά υπόλοιπα, σύμβολα Legendre και Jacobi.
- Υπολογιστική πολυπλοκότητα και αλγόριθμοι για βασικά αριθμοθεωρητικά προβλημάτων: επαναλαμβανόμενος τετραγωνισμός, Ευκλείδειος, επεκτεταμένος Ευκλείδειος, υπολογισμός συμβόλου Jacobi, ρίζες modulo n, έλεγχοι πρώτων αριθμών (Fermat, Solovay-Strassen, Miller-Rabin, αλγόριθμος AKS), παραγοντοποίηση (μέθοδος ρ, μέθοδος Dixon), διακριτός λογάριθμος (Shanks, Pohling-Hellman, index-calculus).
- Συμμετρικά κρυπτοσυστήματα: πακέτου (DES, AES), ροής (stream ciphers). Τρόποι λειτουργίας.
Κρυπτοσυστήματα δημοσίου κλειδιού: RSA, ElGamal. Ανταλλαγή κλειδιού Diffie-Hellman.
- Σχήματα ψηφιακών υπογραφών (RSA, DSS), υπογραφές ειδικού σκοπού (μιας χρήσης, τυφλές, αδιαμφισβήτητες).
- Κρυπτογραφικά πρωτόκολλα (διαμοιρασμού μυστικού, ρίψης νομίσματος, ανταλλαγής κλειδιού).
- Αποδείξεις ασφάλειας βασισμένες σε γενικά παραδεκτές υποθέσεις υπολογιστικής δυσκολίας, μοντέλα ασφάλειας (KPA, CPA, CCA, IND-CPA, IND-CCA), κρυπτογραφικές αναγωγές.
- Συναρτήσεις σύνοψης (hash functions) και συναρτήσεις μονής κατεύθυνσης. Ψευδοτυχαιότητα.
- Αποδείξεις μηδενικής γνώσης. Πρωτόκολλα ταυτοποίησης.
- Προηγμένα θέματα: κβαντική και μετα-κβαντική κρυπτογραφία, ελλειπτικές καμπύλες, σύνθεση πρωτοκόλλων, διγραμμικές απεικονίσεις, κρυπτογραφία με lattices.
title: 01_0424
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Development of structural correlations and synchronization from adaptive rewiring in networks of Kuramoto oscillators
Creators: name: Papadopoulos, Lia
name: Kim, Jason
name: Kurths, Jurgen
name: Bassett, Danielle S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences

description: Synchronization of non-identical oscillators coupled through complex networks is an important example of collective behavior. It is interesting to ask how the structural organization of network interactions influences this process. Several studies have uncovered optimal topologies for synchronization by making purposeful alterations to a network. Yet, the connectivity patterns of many natural systems are often not static, but are rather modulated over time according to their dynamics. This co-evolution - and the extent to which the dynamics of the individual units can shape the organization of the network itself - is not well understood. Here, we study initially randomly connected but locally adaptive networks of Kuramoto oscillators. The system employs a co-evolutionary rewiring strategy that depends only on instantaneous, pairwise phase differences of neighboring oscillators, and that conserves the total number of edges, allowing the effects of local reorganization to be isolated. We find that a simple regulatory rule - which preserves connections between more out-of-phase oscillators while rewiring connections between more in-phase oscillators - can cause initially disordered networks to organize into more structured topologies that support enhanced synchronization dynamics. We examine how this process unfolds over time, finding both a dependence on the intrinsic frequencies of the oscillators and the global coupling. For large enough coupling and after sufficient adaptation, the resulting networks exhibit degree - frequency and frequency - neighbor frequency correlations. These properties have previously been associated with optimal synchronization or explosive transitions. By considering a time-dependent interplay between structure and dynamics, this work offers a mechanism through which emergent phenomena can arise in complex systems utilizing local rules.
description: 14 pages, 10 figures in the main; also includes and appendix and supplement
Characterizing and Engineering Thioesterases as Biocatalysts for Macrocyclization
Creators: name: Brazeau-Henrie, Jordan
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2024
Subjects: Thioesterases
Biocatalysis
Macrocyclization
Protein engineering
Chemoenzymatic synthesis

description: Natural products (NP) present themselves as complex molecules with useful and potent biological activities. Notably, macrocyclic NP have garnered significant attention for defying the prototypical "rule of 5" yet retaining optimal pharmacological properties, and the ability to bind to targets with high affinity and specificity. While synthetic macrocyclization poses considerable challenges, nature effortlessly generates these complex molecules using thioesterase (TE) domains positioned at the C-terminus of modular biosynthetic machinery. This has spurred researchers to explore the use of TEs as in vitro macrocyclization biocatalysts, enabling the chemoenzymatic synthesis of numerous macrocycles. In the context of the existing literature on TEs, we proposed two models to provide a rational framework for understanding TE-mediated macrocyclization. The research presented here describes the characterization of two non-ribosomal peptide synthetase (NRPS) TE domains and their use as biocatalysts for the chemoenzymatic synthesis of two cyclic depsipeptide NP. Unlike other characterized NRPS TEs, these two demonstrated the ability to catalyze macrolactonization with minimal competing hydrolysis reactivity, making them promising biocatalysts. An uncommon tandem TE domain was also characterized, revealing its tolerance for N-terminal peptide modification, peptide sequence composition and stereochemical configuration of the nucleophile used for ring closure. These attributes make it a compelling candidate for the development of a general peptide macrocyclization biocatalyst. Finally, the first extensive engineering of a polyketide synthase (PKS) TE was undertaken via a rational protein design approach and an LCMS-based screening method. Four variants were identified with improved macrocyclization activity over wild-type (WT), highlighting the utility and success of TE protein engineering. This pioneering engineering project serves as a foundation for future TE engineering projects that will generate useful enzymes with optimized activities. Overall, the research presented further develops the field of macrocyclization biocatalysis by showcasing the utility and engineering of TE domains.
title: Metabolic modeling of synthesis gas fermentation in bubble column reactors
Creators: name: Chen, Jin
name: Gomez, Jose A.
name: Höffner, Kai
name: Barton, Paul I.
name: Henson, Michael A.
Publisher: name: University of Massachusetts Amherst
Year: 2015
Subjects: subject: metabolic modeling
subject: bioprocess engineering
subject: microbial fermentation
subject: ethanol production

description: Background A promising route to renewable liquid fuels and chemicals is the fermentation of synthesis gas (syngas) streams to synthesize desired products such as ethanol and 2,3-butanediol. While commercial development of syngas fermentation technology is underway, an unmet need is the development of integrated metabolic and transport models for industrially relevant syngas bubble column reactors. Results We developed and evaluated a spatiotemporal metabolic model for bubble column reactors with the syngas fermenting bacterium Clostridium ljungdahlii as the microbial catalyst. Our modeling approach involved combining a genome-scale reconstruction of C. ljungdahlii metabolism with multiphase transport equations that govern convective and dispersive processes within the spatially varying column. The reactor model was spatially discretized to yield a large set of ordinary differential equations (ODEs) in time with embedded linear programs (LPs) and solved using the MATLAB based code DFBAlab. Simulations were performed to analyze the effects of important process and cellular parameters on key measures of reactor performance including ethanol titer, ethanol-to-acetate ratio, and CO and H2 conversions. Conclusions Our computational study demonstrated that mathematical modeling provides a complementary tool to experimentation for understanding, predicting, and optimizing syngas fermentation reactors. These model predictions could guide future cellular and process engineering efforts aimed at alleviating bottlenecks to biochemical production in syngas bubble column reactors.
Additional file 1 of The role of maternal age on the risk of preterm birth among singletons and multiples: a retrospective cohort study in Lombardy, Norther Italy
Creators: name: Esposito, Giovanna
name: Mauri, Paola Agnese
name: Cipriani, Sonia
name: Franchi, Matteo
name: Corrao, Giovanni
name: Parazzini, Fabio
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Additional file 1.
Sonochemical synthesis of methyl-4-(hetero)arylmethylene isoxazole-5(4H)-ones using SnII-montmorillonite
Creators: name: Ahmadzadeh, Majid
name: Zohre Zarnegar
name: Safari, Javad
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Marine Biology

description: Tin exchanged montmorillonite K10 (SnII-Mont K10) was prepared by ion exchange between SnCl2 and montmorillonite K10. The SnII-Mont K10 was characterized by X-ray diffraction, scanning electron microscope and energy-dispersive X-ray spectroscopy. The synthesized SnII-Mont K10 was used as a recoverable solid catalyst for synthesis of 3-methyl-4-arylmethylene isoxazole-5(4H)-ones via one-pot multicomponent cyclocondensation of hydroxylamine hydrochloride, ethyl acetoacetate and benzaldehyde derivatives in water under ultrasound irradiations. The yields of products were obtained 87–96%. The remarkable advantages of this method are a low-cost and eco-friendliness catalyst, rapid completion of the reactions, and avoidance of using organic solvents, excellent yield and mild conditions.