cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Cochrane systematic reviews of mutation specific therapies for patients with cystic fibrosis
Creators: name: Patel, Sanjay
Publisher: name: University of Liverpool Repository
Year: 2015

description: Cystic Fibrosis (CF) is the most common inherited condition amongst people of European descent. It is caused by a mutation in the CFTR gene located on chromosome 7, and codes for the CFTR protein. Mutations in the CFTR gene lead to the characteristic features of CF, namely progressive and irreversible lung disease which is responsible for the majority of premature deaths in CF. Recently, research into the management of CF has shifted towards personalised genomic medicine. New classes of drugs called mutation-specific-therapies have been designed to target the mutation specific defects in CFTR protein synthesis or function. They have shown to restore the gating defect of class III mutations (CFTR potentiators) and intracellular processing defect of class II mutations (CFTR correctors) in cell studies. Both CFTR potentiators and CFTR correctors have progressed to human clinical trials. Cochrane systematic reviews are the gold standard for establishing the current evidence base for interventions. Objective To conduct two Cochrane systematic reviews to evaluate the benefits and harms of 1) CFTR potentiators (for class III-IV mutations) and 2) CFTR correctors (for class II mutations) on clinically important outcomes in children and adults with CF. Methods Systematic reviews were conducted according to peer assessed and published review protocol. Relevant studies were identified by searching the Cochrane Cystic Fibrosis Trials Register, compiled from electronic database searches and hand searching of journals and conference abstract books. We also searched the clinical trial registries maintained by the EMA, the US NIH and the WHO and contacted leading researches and industry for relevant trials. We included only RCTs of parallel design that met pre-defined eligibility criteria. Two authors independently extracted data and assessed the risk of bias in included trials. If appropriate, data were combined in a meta-analysis. Results Studies with patients with the G551D mutation demonstrated a clinically relevant impact of Ivacaftor on outcomes at 24 and 48 weeks providing evidence for the use of Ivacaftor (CFTR potentiator) in patients with G551D mutation (Class III). There is no evidence to support the short-term use of CFTR correctors, CFTR potentiators, or both as combination therapy in patients with the ΔF508 mutation (class II mutation). As patients with Class II mutations comprise a significant proportion of all CF patients, identifying an efficacious CFTR corrector (or CFTR corrector and CFTR potentiator combination) will have a profound impact on the field.
Durable change in glycaemic control following intensive management of type 2 diabetes in the ACCORD clinical trial
Creators: name: Largay, Joseph F.
name: Sood, Ajay
name: Gerstein, Hertzel C.
name: Riddle, Matthew C.
name: Ismail-Beigi, Faramarz
name: Brillon, David J.
name: Simmons, Debra L.
name: Hramiak, Irene
name: Bergenstal, Richard M.
name: Punthakee, Zubin
name: Miller, Michael E.
name: Savage, Peter J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: We aimed to determine the persistence of glycaemic control 1 year after a limited period of intensive glycaemic management of type 2 diabetes.
Eighteen year weight trajectories and metabolic markers of diabetes in modernising China: which timescale is most relevant? Reply to Vistisen D and Færch K [letter]
Creators: name: Popkin, Barry M.
name: Adair, Linda S.
name: Gordon-Larsen, Penny
name: Thompson, Amanda L.
name: Paynter, Lauren
name: Herring, Amy H.
name: Howard, Annie Green
name: Koehler, Elizabeth
name: Mayer-Davis, Elizabeth J.
name: Zhang, Bing
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Aims/HypothesisAlthough obesity is a major risk factor for diabetes, little is known about weight gain trajectories across adulthood, and whether they are differentially associated with metabolic markers of diabetes.MethodsWe used fasting blood samples and longitudinal weight data for 5,436 adults (5,734 observations, aged 18–66years) from the China Health and Nutrition Survey (1991–2009). Using latent class trajectory analysis, we identified different weight gain trajectories in six age and sex strata, and used multivariable general linear mixed effects models to assess elevated metabolic markers of diabetes (fasting glucose, HbA1c, HOMA-IR, insulin) across weight trajectory classes. Models were fitted within age and sex strata, and controlled for baseline weight (or baseline weight by weight trajectory interaction terms), height, and smoking habit, with random intercepts to control for community-level correlations.ResultsCompared with weight gain, classes with weight maintenance, weight loss, or a switch from weight gain to loss had lower values for metabolic markers of diabetes. These associations were stronger among younger women (aged 18–29 and 30–39years) and men (18–29years) than in older (40–66years) men and women. An exception was HOMA-IR, which showed class differences across all ages (at least p < 0.004).ConclusionTrajectory analysis identified heterogeneity in adult weight gain associated with diabetes-related metabolic markers, independent of baseline weight. Our findings suggest that variation in metabolic markers of diabetes across patterns of weight gain is masked by a homogeneous classification of weight gain.Electronic supplementary materialThe online version of this article (doi:10.1007/s00125-014-3284-y) contains peer-reviewed but unedited supplementary material, which is available to authorised users.
Affleck-Dine Sneutrino Inflation
Creators: name: Evans, Jason L.
name: Gherghetta, Tony
name: Peloso, Marco
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Motivated by the coincidence between the Hubble scale during inflation and the typical see-saw neutrino mass scale, we present a supergravity model where the inflaton is identified with a linear combination of right-handed sneutrino fields. The model accommodates an inflaton potential that is flatter than quadratic chaotic inflation, resulting in a measurable but not yet ruled out tensor-to-scalar ratio. Small CP-violation in the neutrino mass matrix and supersymmetry breaking yield an evolution in the complex plane for the sneutrino fields. This induces a net lepton charge that, via the Affleck-Dine mechanism, can be the origin of the observed baryon asymmetry of the universe.
description: 5 pages, 1 figure
Medications for type 2 diabetes: how will we be treating patients in 50 years?
Creators: name: Buse, John B.
name: Kahn, Steven E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The past 50 years have seen the development of many new options for treating and preventing type 2 diabetes. Despite this success, the individual and societal burden of the disease continues unabated. Thus, the next 50 years will be critical if we are going to quell the major non-communicable disease of our time. The knowledge we will gain in the next few years from clinical studies will inform treatment guidelines with regard to which agents to use in whom and whether more aggressive approaches can slow the development of hyperglycaemia in those at high risk. Beyond that, we anticipate identification of novel targets and techniques for therapeutic intervention. These advances will lead to more personalised approaches to treatment. Most importantly, we will need to focus our political and economic efforts on enhancing and implementing public health approaches aimed at prevention of diabetes and its co-morbidities. This is one of a series of commentaries under the banner ‘50 years forward’, giving personal opinions on future perspectives in diabetes, to celebrate the 50th anniversary of Diabetologia (1965–2015).
Textile Trajectories
Creators: name: Marr, Anne
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Full paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
title: External threats mask internal fears: Edwardian invasion literature 1899-1914
Creators: name: Wood, Harry
Publisher: name: University of Liverpool Repository
Year: 2015

description: Invasion literature is a branch of fiction that enjoyed significant popularity in Britain prior to the First World War. Focusing on invasion narratives of the Edwardian period, this thesis foregrounds the literature’s representation of domestic political issues. These include debates over national identity, the campaign for compulsory military service, and the sociopolitical upheavals of the late-Edwardian period. Through emphasising the importance of these internal themes, the thesis argues that such narratives were vehicles for multifaceted critiques of British society rather than one-dimensional predictions of invasion. Exploring the ideological origins of these narratives, the thesis questions the dominant understanding that invasion literature was a Tory product. The genre is instead interpreted as a product of the British ‘Radical Right’. Presenting invasion literature as a repository of varied contemporary anxieties, the thesis reconsiders the analytical value of the ‘Edwardian Crisis’, arguing that narratives of invasion illustrate a pronounced sense of approaching crisis. This thesis therefore offers an original contribution to modern British political and cultural history, and invasion literature studies.
Acute HIV infection among pregnant women in Malawi
Creators: name: Cohen, Myron S.
name: Kwiek, Jesse J.
name: Gay, Cynthia L.
name: Mwapasa, Victor
name: Meshnick, Steven R.
name: Fiscus, Susan A.
name: Murdoch, David M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: There are limited data on acute HIV infection (AHI) prevalence during pregnancy.
Longitudinal Machine Learning Model for Predicting Systolic Blood Pressure in Patients with Heart Failure
Creators: name: Najafi-Vosough, Roya
name: Faradmal, Javad
name: Hosseini, Seyed Kianoosh
name: Moghimbeigi, Abbas
name: Mahjub, Hossein
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: Systolic Blood Pressure; Heart Failure; Least Squares Support Vector Regression; Longitudinal data
Heart Failure

description: Objective: Systolic blood pressure (SBP) is a powerful prognostic factor in heart failure (HF) patients, which is associated with death and readmission. Therefore, control of blood pressure is an important element for managing these patients. The goal of this study was to compare the performance of classical and machine learning models for predicting SBP and identify important variables related to SBP changes over time. Methods: The information of 483 HF patients was analyzed in this retrospective cohort study. These patients were hospitalized at least twice in Farshchian Heart Center Hamadan province, the west of Iran, between October 2015 and July 2019. We applied a linear mixed-effects model (LMM) and mixed-effects least-square support vector regression (MLS-SVR) for predicting SBP. The performance of both models was assessed by mean absolute error, and root mean squared error. Results: Based on LMM results, there was a significant association between sex, body mass index (BMI), sodium, time, and history of hypertension with SBP changes over time (P-value <0.05). Also, MLS-SVR indicated that the four most important variables were history of hypertension, sodium, BMI, and triglyceride. The performance of MLS-SVR compared to LMM was better in both training and testing datasets. Conclusions: According to our results, BMI, sodium, and history of hypertension were the important variables on SBP changes in both LMM and MLS-SVR models. Also, it seems that MLS-SVR can be used as an alternative for classical longitudinal models for predicting SBP in HF patients.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
title: Use of Cotrimoxazole Prophylactic treatment in HIV exposed children and its impact on malaria
Creators: name: Mbeye, Nyanyiwe
Publisher: name: University of Liverpool Repository
Year: 2015

description: The rapidly growing population of HIV exposed children entails widespread use of cotrimoxazole prophylactic treatment (CPT) to protect them from HIV opportunistic infections given their increased susceptibility compared to non-HIV exposed children. A number of studies have reported that CPT also provides protection against malaria but estimates of its effectiveness vary and there is little information on the impact of the prevalence of antifolate resistance mutations on its effect. Since daily CPT provides prophylaxis against malaria, it could modulate the development of malaria-specific immunity and increase the incidence of malaria after it is stopped (a rebound effect). Moreover, factors that influence CPT adherence in this group are not known. This thesis reviewed studies that examined the effect of CPT provided at the age of 6 weeks to 14 months on malaria incidence in children in Sub-Saharan Africa (systematic review) and investigated the incidence of malaria and other morbidities during and after CPT in the first two years of life in HIV exposed children in southern Malawi (cohort study). Lastly, CPT adherence was explored using narrative and grounded theory approaches (qualitative study). Results The systematic review included 3 Randomised Controlled Trials (RCTs) and four cohort studies fulfilling the eligibility criteria, with a total of 5,978 children (1,692 HIV exposed; 2,800 non-HIV exposed; 1,486 HIV-infected). Children on CPT were less likely to develop clinical malaria episodes than those without prophylaxis (combined Incidence Rate Ratio (IRR) = 0·37, 95% CI 0·21, 0·66) but there was substantial between-study heterogeneity (I-squared=94%, p
Knowledge and Identity Antecedents of COVID-19 vaccine status: A Study of South Carolina Residents
Creators: name: Travis, Justin
name: Webb, Ginny
name: Mercado, Brandon
name: Phan, Colleen
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: COVID-19
vaccine hesitancy
vaccine knowledge
Health Education
infectious diseases social psychology
COVID-19 Vaccine
Vaccine Hesitancy

description: Background: After nearly four years of living in a pandemic due to the Corona virus, and almost three years after developing multiple vaccines, vaccination rates remain suboptimal, thereby preventing our society from reaching herd immunity. Purpose: Extant literature on vaccine hesitancy led us to hypothesize that specific socio/political variables may be contributing to low vaccination rates, particularly in South Carolina. Method: By use of Qualtrics surveys, we collected data from people across all counties in South Carolina regarding vaccine status, plans to vaccinate, and a host of demographics. Results: Findings revealed that those less likely to be vaccinated against COVID-19 tended to be younger, female, republican. Interestingly, COVID-19 knowledge did not appear to differ between vaccination status groups, although COVID-19 vaccine and general vaccine knowledge did differ. Conclusions: While understanding of COVID-19 was relatively similar across groups, targeted and tailored interventions aimed at enhancing the public’s general and COVID-19-specific vaccine knowledge may aid efforts to reach herd immunity. Keywords: COVID-19, vaccine hesitancy, vaccine knowledge
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
Sound absorbing textile surfaces in the urban landscape - collaborative research in textile and architectural design
Creators: name: Fridh, Kristina
name: Zetterblom, Margareta
name: Femenias, Paula
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Full paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
title: Chromatic driver fatigue monitoring system
Creators: name: Koh Ker Keong, Alex
Publisher: name: University of Liverpool Repository
Year: 2023

description: Sleep related vehicle accidents have been under publicised but remains as one of the main causes of road traffic accidents, as much as drink driving. This research aims to reduce this worldwide problem by developing a system to monitor fatigue driving. The thesis describes the research into the application of chromatic data processing techniques to detect early physiological and physical indicators of fatigue. Physiological factors that influence drivers are based on the duration of the drive, how much rest they have throughout the journey and the quality of sleep they had prior to the drive. The physiological indicator algorithm of the system is developed to take account of these factors and calculates the tiredness level. The chromatic technique is then used to analyse the results to establish trends and signatures of early fatigue situations where a warning system can be introduced. The chromatic signatures of fatigue have been established using results from 20 road tests conducted by professional drivers. Physical indicators such as early drowsy driving are detected by monitoring the behaviour of the vehicle. Micro sleep (e.g. head nodding, slow eye-blinking) can lead to lane drifting and vehicle swerving. These events are being regarded as early physical signs of sleepy driving. The main sensor for detecting the lateral yaw motion of the vehicle is a miniaturised gyroscope. Chromatic analysis is applied to the gyroscope output to identify and differentiate fatigue related events (e.g. swerves and lane drifting) from normal driving (e.g. left and right turning, roundabouts and bumpy roads) Combining the extracted information of the physiological and physical indicators, a Chromatic Fatigue Driving System can be developed as a tail safe system which monitors and alerts driver during critical fatigue conditions.
title: Continuous proliferation and simultaneous maturation of haematopoietic stem cells into blood cell lineages
Creators: name: van Veen, Hendrik Theun
Publisher: name: University of Liverpool Repository
Year: 2015

description: For decades, research has been focussed on finding a way to produce artificial blood as a resolution for the insufficient amount of blood components provided by donation and to provide a more transportable alternative with a longer shelf life. Red blood cells (RBCs) are the most common cell type in blood and are responsible for oxygen transport throughout the human body. It is therefore extremely important to find an alternative oxygen carrier whether these are tissue engineered RBCs or a chemically defined oxygen delivery system The study conducted for this thesis was part of a larger project called Redontap, and was aimed to develop a bioreactor for the manufacture of RBCs. During this research to produce RBCs from adult stem cells in vitro, the main goal was to upscale haematopoietic and erythroid cultures. Understanding the biological signals and their temporal magnitude involved in the division, maturation and migration of the CD34+ haematopoietic stem cells (HSCs) and their differentiated progeny would allow for a controlled continuous production of mature blood cells. The differentiation of HSCs into different blood cell types occurs within different bone marrow niches and so mimicry of the erythrocyte niche is likely to result in maximisation of the rate of red blood cell development. Published research provides evidence that peripheral blood mononuclear cells (PBMCs), including CD34- cells, will be advantageous for erythroid maturation. For this thesis, CD34+ cells were expanded within a population of PBMCs on a stromal layer to recreate a niche-like environment. This approach was also utilised with umbilical cord blood isolated MNCs (UBMCs) to compare HSC expansion potential and subsequently efficiency in erythroid maturation was analysed. Whereas the cell output was limited, differentiated cells proved positive for a range of RBC surface markers and haemoglobin content. As part of the aim for upscaling cell culture by translating static cultures to bioreactor processes, bioreactors with volumes varying between 250mL-3L were analysed for cell retention and viability to achieve high cell densities whilst refreshing culture medium, monitoring culture parameters (e.g. pH, dissolved oxygen), and introducing an hypoxia environment for mimicking the in vivo stem cell niche. In general, this research was focussed on improving dynamic culture conditions for generating higher numbers of cultured erythrocytes than so far has been achieved.
Low prevalence of Pneumocystis jirovecii lung colonization in Ugandan HIV-infected patients hospitalized with non-Pneumocystis pneumonia
Creators: name: Worodria, William
name: Cattamanchi, Adithya
name: Huang, Laurence
name: Taylor, Steve M.
name: Yoo, Samuel D.
name: Goodman, Carol D.
name: Andama, Alfred
name: Meshnick, Steven R.
name: Davis, J. Lucian
name: den Boon, Saskia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Pneumocystis jirovecii is an important opportunistic infection in HIV-infected patients. In the developed world, P. jirovecii epidemiology is marked by frequent colonization in immunosuppressed patients, but data on the prevalence of colonization is very limited in sub-Saharan Africa, where the majority of persons living with HIV reside. Our objective was to describe the epidemiology of P. jirovecii colonization among HIV-positive patients in a cross-sectional, hospital-based study of patients admitted with suspected pneumonia in Kampala, Uganda. P. jirovecii was detectable in bronchoalveolar lavage fluid from 7 of 124 (6%) consecutive patients with non-Pneumocystis pneumonia. Colonization was not associated with patient demographic or clinical information. This prevalence is substantially lower than in published studies in the developed world, and suggests that there is a limited reservoir of organisms for clinical infections in this Ugandan population. These findings may partially explain the low incidence of Pneumocystis pneumonia in Uganda and other sub-Saharan African countries.
Factors Influencing The First Thousand Days Of Life
Creators: name: Capitani, Elena
name: Carlotta, Lorenzini
name: Adele, Biuzzi
name: Lucia, Alaimo
name: Nicola, Nante
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: nurturing care
social support
Maternal and Child Health

description: Background: WHO, Unicef, the World Bank and the Maternal and Child Health Partnership wrote the document "Nurturing care for early child development: a global framework action".This paper highlights the benefits of early intervention and thus the need to invest more in health during this period.The aim of our study is to assess how much social support received by pregnant mothers can influence maternity outcomes. Materials and Methods: The retrospective observational study was conducted on a sample of mothers enrolled via social networks, who were administered a questionnaire from 1 July to 1 September 2021.The questionnaire consisted of 37 questions, 6 of which were used to calculate the "Maternity Social Support Scale".The ODDs Ratio was calculated. Results:Our sample consisted of 3447 women. 59.01% were between 26 and 35 years of age.The mean Maternity Social Support Scale (MSSS) score was calculated to be 23.9 points.A low MSSS score correlated with a higher probability of stopping breastfeeding before 6 months of age(OR:1. 2;C.I:1.1-1.4) and of having a caesarean section(OR:1.2;C.I:1.1-1.4) and to a lower probability of having a spontaneous labour(OR:0.9;C.I:0.7-0.9) and a spontaneous delivery(OR:0.8;C.I:0.7-0.9). In contrast, a high MSSS score had a lower likelihood of ceasing breastfeeding before 6 months (OR:0.8;C.I:0.7-0.9) and caesarean section(OR:0.8;C.I:0.7-0.9) and higher likelihood of spontaneous onset labour(OR:1.2;C.I:1.1-1.3) and spontaneous delivery(OR:1.2;C.I:1.1-1.4). Conclusions:Pregnancy, childbirth and maternity outcomes are strongly influenced and conditioned by the social context in which they occur and the support the woman may receive.The presence or lack of this support may affect the health of newborns.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
title: Oil, gas and minerals: the impact of resource-dependence and governance on sustainable development
Creators: name: Carbonnier, Gilles
name: Brugger, Fritz
name: Wagner, Natascha
Publisher: name: Graduate Institute of International and Development Studies
publisherIdentifier: https://ror.org/007ygn379
publisherIdentifierScheme: ROR
Year: 2011

description: CCDP Working Paper ; no. 8
Can a UV-C box help the cinema industry by disinfecting video cameras?
Creators: name: Amodeo, Davide Amodeo
name: Limaj, Sandro
name: De Palma, Isa
name: Nanate, Nicola
name: Cevenini, Gabriele
name: Messina, Gabriele
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: UV-C LED
E. coli
MRSA
SARS-COV-2
cinema
video camera
Disinfection
Health technology assessment
disease prevention and promotion

description: UV-C has proven to be an effective virucide and microbicide, and its cost-effectiveness allowed it to spread as a disinfecting device in different environments. The study aims to determine the microbicide activity on S. Aureus, E. Coli and Sars-CoV-2 of the UV-C Boxer by Cartoni S.p.A. Three separate experiments were performed to assess the effectiveness of the UV-C disinfection by the box on different materials, on surfaces of a videocamera and on a specific carrier for Sars-CoV-2. In all three experiments, a significant abatement of bacterial and viral contamination was reached after 60 seconds on carriers and after 3 minutes on all examined surfaces of the video camera, with a higher reduction on glass carriers. UV-C devices may be a valuable tool to implement in the working routine to achieve a higher level of safety in work environments.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
Clark Kent vs. Superman: Unmasking the Actual Superheroes of Haute Couture
Creators: name: Liggett, Dean
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Full paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
The hidden craft of costume construction: an exploration from the makers' perspective
Creators: name: Garland, Liz
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Full paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
Atypical Epstein-Barr Viral Genomic Structure in Lymphoma Tissue and Lymphoid Cell Lines
Creators: name: Bryant, Ronald J.
name: Schroeder, Jane
name: Fan, Hongxin
name: Tang, Weihua
name: Gulley, Margaret L.
name: Dunphy, Cherie H.
name: Fedoriw, Yuri
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Epstein-Barr virus (EBV) DNA is found within the malignant cells of some subtypes of lymphoma, and viral presence is being exploited for improved diagnosis, monitoring, and management of affected patients. Recent work suggests that viral genomic polymorphism, such as partial deletion of the viral genome, could interfere with virus detection in tumor tissues. To test for atypical forms of the EBV genome, 98 lymphomas and 6 infected cell lines were studied using a battery of 6 quantitative polymerase chain reaction assays targeting disparate sections of EBV DNA. Fifty of the lymphomas (51%) had no amplifiable EBV DNA, and 38 lymphomas (39%) had low-level EBV infection that was deemed incidental based on EBV-encoded RNA (EBER) in situ hybridization results. The remaining 10 lymphomas (10%) had high EBV loads and EBER localization to malignant cells by EBER in situ hybridization. All 10 represented lymphoma subtypes were previously associated with EBV (Burkitt, diffuse large B-cell, or T-cell type), whereas no remnants of EBV were detected in other lymphoma subtypes (follicular, small lymphocytic, mantle cell, or marginal zone type). Interestingly, 4 of the 10 infected lymphomas had evidence of atypical viral genomes, including 3 of 4 infected T-cell lymphomas with aberrant loss of LMP2 amplicons, and a single diffuse large B-cell lymphoma lacking the central part of the viral genome spanning BamH1W, BZLF1, and EBNA1 gene segments. A reasonable screening strategy for infected malignancy involves applying EBER1 and LMP1 quantitative polymerase chain reaction assays and confirming that values exceeding 2000 copies of EBV per 100,000 cells have EBER localization to malignant cells.
title: Caution & distortion: consuming narratives of violent actors and spaces in Colombian cultural products: 1990-2005.
Creators: name: Parry, Sarah
Publisher: name: University of Liverpool Repository
Year: 2015

description: This thesis analyses representations of urban violence in Colombia within four cultural products published/released in the time period 1990 to 2005 . The cultural products belong to genres commonly regarded as distinct, and divided between ‘fiction’ and ‘non-fiction’ – a novel, film, ‘testimonio’ and documentary. Methodologically, the analysis focuses on each cultural product as a whole – the text itself and its marketing paratext. In this focus on the cultural product as a whole, it also considers the role of the audience in the consumption of the cultural products and their themes. The theme the thesis specifically engages with is the representation of violent actors, and focuses in particular on their status as fourth world inhabitants. The fourth world is a theoretical category developed by Manuel Castells to describe spaces which are excluded from global networks and flows of information, resulting in ‘black holes’, such as favelas, inner city ‘ghettos’ and slums, in which inhabitants are unable to gain access to services and regular employment. The thesis looks at the development of myths surrounding these spaces and their inhabitants, and the role played by cultural products in constructing and perpetuating divisive myths. It posits a growing globally homogenised representation of the fourth world inhabitant as violent and destructive, creating a binary between fourth and first world inhabitants to which the representations in these particular Colombian cultural products are linked. Overall, the thesis argues that the representation of violent actors in Colombia, and in particular the city of Medellín in this time period, illustrates that the distinction between fiction and non-fiction has collapsed, due to the strength of myths surrounding fourth world figures.
Scaling Laws for Thin Films near the Superconducting-to-Insulating Transition
Creators: name: Tao, Yong
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We propose a Lagrangian function, which combines Landau-Ginzburg term and Chern-Simons term, for describing the competition between disorder and superconductivity. To describe the normal-to-superconducting transition in the thin superconducting films, we apply Wilson's renormalization group methods into this Lagrangian function. Finally, we obtain a scaling law between critical temperature (T_c), film thickness (d), sheet resistance of the film at the normal state (R_s), and number density of the electrons at the normal state (N). Such a scaling law is in agreement with recent experimental investigations [Ivry, Y. et al, Physical Review B 90, 214515 (2014)]. Our finding may have potential benefits for improving transition temperature T_c.
description: 9 pages, 1 table
Endogenous and exogenous electric fields as modifiers of brain activity: rational design of noninvasive brain stimulation with transcranial alternating current stimulation
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Synchronized neuronal activity in the cortex generates weak electric fields that are routinely measured in humans and animal models by electroencephalography and local field potential recordings. Traditionally, these endogenous electric fields have been considered to be an epiphenomenon of brain activity. Recent work has demonstrated that active cortical networks are surprisingly susceptible to weak perturbations of the membrane voltage of a large number of neurons by electric fields. Simultaneously, noninvasive brain stimulation with weak, exogenous electric fields (transcranial current stimulation, TCS) has undergone a renaissance due to the broad scope of its possible applications in modulating brain activity for cognitive enhancement and treatment of brain disorders. This review aims to interface the recent developments in the study of both endogenous and exogenous electric fields, with a particular focus on rhythmic stimulation for the modulation of cortical oscillations. The main goal is to provide a starting point for the use of rational design for the development of novel mechanism-based TCS therapeutics based on transcranial alternating current stimulation, for the treatment of psychiatric illnesses.
Practice patterns in screening for varices: An American survey
Creators: name: Barritt, A.S.
name: Arguedas, M.R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Guidelines recommend screening for gastroesophageal varices. Regional studies suggest screening is underutilized, but information from across the United States is unavailable. We explored practice patterns and adherence to guidelines in a random sample of physicians and sought to define whether differences existed according to practice type, setting and years of practice.
The role of statistical significance in health risk assessment and in the decision-making process
Creators: name: Panteghini, Marco
name: Mansournia, Mohammad Alì
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: health risk assessment, patient-centred medicine, statistical significance, statistical inference
Statistical significance
Health risk assessment
Patient-centred Medicine

description: Not requested
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
title: Agent Risk Management in Electronic Markets Using Option Derivatives
Creators: name: Baqueiro  Espinosa, Omar
Publisher: name: University of Liverpool Repository
Year: 2023

description: In this thesis I present a framework for intelligent software agents to manage risk in electronic marketplaces using Option Derivatives. To compare the perfonnance of agents that trade Option Derivatives with agents not using them, I create a simulation of a financial marketplace in which software agents are vested with decision rules for buying and selling assets and Options. The motivation of my work is the need of risk management mechanisms for those Multi-Agent Systems where resources are allocated according to a market mechanism. Autonomous agents participating in such markets need to consider the risks to which they are exposed when trading in them, and to take actions to manage those risks. This thesis considers the hypothesis that software agents can benefit from trading Option Derivatives, using them as a tool to manage their exposure to uncertainty in the market. The main contributions of this thesis are: First, an abstract framework of an Option trading market is developed. This framework serves as a foundation for the implementation of computational Option trading mechanisms in systems using Market-Based resource allocation. The framework can be incorporated into existing Market-Based systems using the traded resources as the underlying assets for the Option market. Within the framework, four basic Option trading strategies are introduced, some of which reason about the risks exposed by their actions. These strategies are provided as a foundation for the development of more complex strategies that maximise the utility of the trading agents by the use of Options. The second contribution of this thesis is the analysis of the results from simulation experiments perfonned with the implementation of a software Multi-Agent System based on the developed Option trading framework. The system was developed in Java using the Repast simulation platfonn. The experiments were used to test the perfonnance of the developed trading strategies. This research shows that agents which traded Options by choosing actions aiming to minimize their risk perfonned significantly better than agents using other trading strategies, in the majority of the experiments. Agents using this risk-minimizing strategy also observed a lower correlation between the asset price and their returns, for the majority of the experimented scenarios. Agents which traded Options aiming to maximize their returns perfonned better than their peers in the scenarios where the asset price volatility was high. Finally, it was also observed that the perfonnance differential of the strategies increased as the uncertainty about the future price of the asset was increased.
Re-wiring Practice: A Conscious Pedagogy
Creators: name: Hudson-Miles, Sam
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Short paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
Epidemiology and management of oesophageal coin impaction in children
Creators: name: Crockett, Seth D.
name: Sperry, Sarah L.W.
name: Miller, C. Brock
name: Shaheen, Nicholas J.
name: McNeill, Matthew B.
name: Dellon, Evan S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The epidemiology of oesophageal coin impaction in children is poorly understood. We aimed to assess characteristics of patients with coin impaction and identify predictors of type of coin impacted and management strategies.
Clinical characteristics, treatment outcomes, and resource utilization in children and adults with eosinophilic gastroenteritis
Creators: name: Dellon, Evan S.
name: Woosley, John T.
name: Reed, Craig
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Eosinophilic gastroenteritis is a rare condition where eosinophilic inflammation occurs in the gastrointestinal tract in the absence of secondary causes. Little is known regarding aetiology, pathogenesis, or natural history.
Finiteness of the number of minimal atoms in Grothendieck categories
Creators: name: Kanda, Ryo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Representation Theory (math.RT)
subject: Category Theory (math.CT)
subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics
subject: 18E15 (Primary), 16P40, 16D90, 14A22, 13C60 (Secondary)

description: For a Grothendieck category having a noetherian generator, we prove that there are only finitely many minimal atoms. This is a noncommutative analogue of the fact that every noetherian scheme has only finitely many irreducible components. It is also shown that each minimal atom is represented by a compressible object.
description: 10 pages
title: The Masonic Enlightenment: Symbolism, Transition and Change in English Freemasonry during the Eighteenth Century
Creators: name: Harrison, David
Publisher: name: University of Liverpool Repository
Year: 2023

description: This study investigates the transitional phases of English Freemasonry from the midseventeenth century into what can be described as a Masonic Enlightenment during the eighteenth century. This movement was part of a wider enterprising evolution led by the Newtonian experimental natural philosopher Dr. John Theophilus Desaguliers and James Anderson, both members of the London based Grand Lodge founded in 1717 and both staunch Hanoverians. The ritual, along with the accompanying Masonic symbolism, quickly became adopted into what would become known as 'Modem' Freemasonry, which spread its influence around England. One of the aims of this thesis is to assess why it was embraced by some areas, yet rejected by others, such as York. Scholarship to date has avoided analysis of the Masonic ritual, with Freemasonry being seen as a secret society, and many of the original documentation relating to Masonic lodges being held in private collections. The United Grand Lodge of England has only recently opened its 'archive and library to the public, though this has only revealed how much documentary material has either been lost or destroyed. An example of this is the absence of personal correspondence relating to Desaguliers' Masonic ritual changes, despite the evidence that changes where made by him. An objective of this dissertation is to examine why the development of 'Modem' Freemasonry was so successful, and why Desaguliers, and other members ofthe Royal Society were attracted to the Craft. The study will also assess the fermentation of Freemasonry as it transmuted from the 'operative' society into 'a more 'speculative' one during the seventeenth century. Precious little academic work has been published on this aspect of the society, and this study will analyse the contributions of Christopher Wren and Isaac Newton on the development of the Craft, concentrating on their emphasis upon the search for the divine measurement of Solomon's Temple. The later changes to the Masonic ritual reflected their work, displaying themes for the search of lost ancient knowledge set against the backdrop of the construction of Solomon's Temple. In this Masonic quest the ethos ofFreemasonry became shaped by fashionable and attractive concepts ofthe 'New Science' merging with the 'Old Science' of magic and alchemy. These concepts which became appealing in the light ofthe social and political atmosphere of the Whig Oligarchy of early eighteenth century England, will also be discussed, the study concluding with an examination of the overall contribution of the Masonic Enlightenment on English society.
Kawamuracarus polyporus Cook 1967
Creators: name: Pešić, Vladimir
name: Chatterjee, Tapas
name: Bordoloi, Sabitry
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Limnesiidae
Kawamuracarus
Kawamuracarus polyporus

description: Kawamuracarus polyporus Cook, 1967
Records from the study area: Maharashtra, Karnataka—Cook (1967); Prasad (1974); Pešić & Ranga Reddy (2009).
Habitat: Hyporheic interstitial.
Distribution: India.
description: Published as part of Pešić, Vladimir, Chatterjee, Tapas & Bordoloi, Sabitry, 2010, A checklist of the water mites (Acari: Hydrachnidia) of India, with new records and description of one new species, pp. 1-54 in Zootaxa 2617 (1) on page 23, DOI: 10.11646/zootaxa.2617.1.1, http://zenodo.org/record/197964
Association between physical activity and risk of COVID-19 infection or clinical outcomes of the patients with COVID-19; A systematic review and meta-analysis
Creators: name: Halabchi, Farzin
name: Mahdaviani, Behnaz
name: Tazesh, Behnaz
name: Shab-Bidar, Sakineh
name: Selk-Ghaffari, Maryam
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: Exercise, COVID-19, SARS-CoV-2, Systematic Review, Meta-Analysis
A systematic review and meta-analysis

description: Objective: Nowadays, the COVID-19 pandemic has caused serious consequences for global health and economy. The important question is whether the level of physical activity might influence the risk of COVID-19 incidence or clinical outcomes, including the severity or mortality of infected patients. The objective of this systematic review and meta-analysis is to evaluate the association between sufficient physical activity and incidence, hospitalization, severity, recovery, and mortality of COVID-19. Methods: A systematic search of Web of Sciences, PubMed, and Scopus between December 2019 and November 2021 in English language was conducted. Studies were screened based on the inclusion criteria, i.e. observational studies (case-control, prospective or retrospective longitudinal designs, and cross-sectional studies) which have determined the association of physical activity, exercise, sports participation, or sedentary behavior with COVID-19 incidence or outcomes, including mortality, severity, recovery and hospitalization in healthy population or population with any specific comorbidity. Results: Based on eligibility criteria, 27 articles were finally included in the qualitative synthesis. The meta-analysis of five studies evaluating association of physical activity and COVID-19 mortality showed weighted OR of OR of 0.61 (CI 95%: 0.50- 0.75) with heterogeneity (I2= 45.8%, P<0.001) and in seven studies regarding physical activity and COVID-19 hospitalization, weighted OR was 0.541 (CI 95% :0.491 -0.595) with heterogeneity (I2=81.7%, P<0.001). Conclusion: Participating in sufficient physical activity might decrease COVID-19 related hospitalization and mortality. Developing programs to increase physical activity during the COVID-19 pandemic might be an appropriate health strategy.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)