cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Depreciation constituent of the investment system in the Republic of Belarus
Creators: name: Golovkov, Vladimir
name: Primschitz, D.V.
name: Golovkov, Vladimir
name: Primschitz, D.V.
Publisher: name: Unknown
Year: 2007
Subjects: subject: Industrial Organization
subject: Production Economics
subject: depreciation
subject: depreciation costs
subject: depreciation policy
subject: depreciation concept

description: The article is devoted to the processes of the depreciation charges and its usage in enterprises, the present day complexity and the necessity of forming a realistic macro level depreciation concept. Some aspects of forming depreciation policy of an enterprise and its influence on the economic and financial activities of an enterprise as well as the primary features of the naturalistic concept and the international experience of the depreciation charges policy are examined in the article.
Unpicking a Feeling: Interrogating the role of heritage in indigenous collective identity formation on the Caribbean island of Bonaire
Creators: name: Antczak, Oliver
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: Identity
Collective Identity
Caribbean
Heritage
Bonaire
Indianness
Indigenous Identity
Colonialism

description: This research attempts to understand how identity and heritage interface with each other in the colonial context of Bonaire in the Dutch Caribbean. By exploring common understandings of how identity and heritage interact, this work applies theories of Indianness, a felt identity based on the adaptation of indigenous populations to a dominant society. Through the critical analysis of interview data in the context of a heritage survey and a historical analysis, this paper finds that heritage and identity production and maintenance are intimately related to colonialism on Bonaire. While many participants designated heritage based on a feeling of Indianness, there was an opposing group of interviewees who instead contested indigenous heritage and searched for historical and scientific legitimization for their heritage and identities. The research concludes that bottom-up understandings of heritage and identity formation are necessary to effectively manage heritage in colonial contexts.
description: I have received the generous support of the Dorothy Garrod Memorial Fund, the Hughes Hall Travel Grant, and the Division of Archaeology Department Funds.
title: Uncertainty and Speculators in an Auction for Emissions Permits
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Haita-Falah, Corina
Publisher: name: Philipps-Universität Marburg
Year: 2016
Subjects: Economics
Wirtschaft
cap-and-trade program
uniform-price auction
speculators
risk aversion
emissions trading

description: Auctions have become popular as means of allocating emissions permits in the emissions trading schemes developed around the world. Mostly, only a subset of the regulated polluters participate in these auctions along with speculators, creating a market with relatively few participants and, thus, incentive for strategic bidding. I characterize the bidding behavior of the polluters and the speculators, examining the effect of the latter on the profits of the former and on the auction outcome. It turns out that in addition to bidding for compliance, polluters also bid for speculation in the aftermarket. While the presence of the speculators forces the polluters to bid closer to their true valuations, it also creates a trade-off between increasing the revenue accrued to the regulator and reducing the profits of the auction-participating polluters. Nevertheless, the profits of the latter increase in the speculators' risk aversion.
The Multi-slit Approach to Coronal Spectroscopy with the Multi-slit Solar Explorer (MUSE)
Creators: name: De Pontieu, Bart
name: Martinez-Sykora, Juan
name: Testa, Paola
name: Winebarger, Amy
name: Daw, Adrian
name: Hansteen, Viggo
name: Cheung, Mark C. M.
name: Antolin, Patrick
name: team, the MUSE
Publisher: name: arXiv
Year: 2019
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The Multi-slit Solar Explorer (MUSE) is a proposed mission aimed at understanding the physical mechanisms driving the heating of the solar corona and the eruptions that are at the foundation of space weather. MUSE contains two instruments, a multi-slit EUV spectrograph and a context imager. It will simultaneously obtain EUV spectra (along 37 slits) and context images with the highest resolution in space (0.33-0.4 arcsec) and time (1-4 s) ever achieved for the transition region and corona. The MUSE science investigation will exploit major advances in numerical modeling, and observe at the spatial and temporal scales on which competing models make testable and distinguishable predictions, thereby leading to a breakthrough in our understanding of coronal heating and the drivers of space weather. By obtaining spectra in 4 bright EUV lines (Fe IX 171A, Fe XV 284A, Fe XIX-XXI 108A) covering a wide range of transition region and coronal temperatures along 37 slits simultaneously, MUSE will be able to "freeze" the evolution of the dynamic coronal plasma. We describe MUSE's multi-slit approach and show that the optimization of the design minimizes the impact of spectral lines from neighboring slits, generally allowing line parameters to be accurately determined. We also describe a Spectral Disambiguation Code to resolve multi-slit ambiguity in locations where secondary lines are bright. We use simulations of the corona and eruptions to perform validation tests and show that the multi-slit disambiguation approach allows accurate determination of MUSE observables in locations where significant multi-slit contamination occurs.
description: 51 pages, 17 figures, submitted to Astrophysical Journal
On entanglement-assisted classical capacity
Creators: name: Holevo, A. S.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: This paper is essentially a lecture from the author's course on quantum information theory, which is devoted to the result of C. H. Bennett, P. W. Shor, J. A. Smolin and A. V. Thapliyal (quant-ph/0106052) concerning entanglement-assisted classical capacity of a quantum channel. A modified proof of this result is given and relation between entanglement-assisted and unassisted classical capacities is discussed.
description: 10 pages, LATEX
Parelasmopus Stebbing 1888
Creators: name: Lowry, J. K.
name: Hughes, L. E.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Maeridae
Parelasmopus

description: Parelasmopus Stebbing, 1888
 Parelasmopus Stebbing, 1888: 1029. — Stebbing, 1906: 417. —J.L. Barnard, 1972a: 253 — Barnard & Barnard, 1983: 629, fig. 10. — Lowry & Stoddart, 2003: 185 (catalogue).
 Type species. Megamoera suensis Haswell, 1879b, here selected (replacing Gammarus suluensis Dana, 1852).
 Included species. Parelasmopus includes 10 species: P. albidus (Dana, 1852); P. echo J.L. Barnard, 1972a; P. dancaui Ortiz & Lalana, 1997; P. mallacootaformis Ledoyer, 1984; P. setiger Chevreux, 1901; P. sowpigensis Lowry & Springthorpe, 2005; P. suensis (Haswell, 1879b); P. suluensis (Dana, 1852); P. ya J.L. Barnard, 1972a; P. zelei Ledoyer, 1983.
 Remarks. Stebbing (1888) based the genus Parelasmopus on Gammarus suluensis Dana, 1852. According to J.L. Barnard (1972a), Stebbing (1888) misidentified his material. Stebbing based his concept of Parelasmopus on a species with a pair of dorsal spines on pereonite 7, but pereonite 7 is smooth in P. suluensis. At that time Barnard could not identify the species, but comparing Stebbing’s (1888) illustrations with Berents’ (1983) illustrations of the lectotype of P. suensis, it is clear that Stebbing had P. suensis. In reality Stebbing based his description of Parelasmopus on P. suensis, using material from Challenger station 186, near Thursday Island, Torres Strait (10º30’S 142º18’E). According to ICZN (4 th edition, 1999) Article 70.3.1, this species may be selected as the type species, replacing Parelasmopus suluensis (Dana, 1852), originally chosen by Stebbing (1888).
description: Published as part of Lowry, J. K. & Hughes, L. E., 2009, Maeridae, the Elasmopus group *, pp. 643-702 in Zootaxa 2260 (1) on pages 690-691, DOI: 10.11646/zootaxa.2260.1.33, http://zenodo.org/record/5361655
GROWTH AND HEMATOLOGICAL PARAMETERS OF CHICKENS UNDER THE ACTION OF WORMWOOD EXTRACT
Creators: name: Chudak, R.A.
Publisher: name: Colloquium-journal
Year: 2021
Subjects: replacement young
wormwood extract
growth
safety
hematological parameters.

description: The article presents the research results on productive and metabolic effects of wormwood extracts used in the feeding of young laying hens.
Metamorphosis of plasma turbulence-shear flow dynamics through a transcritical bifurcation
Creators: name: Ball, R.
name: Dewar, R. L.
name: Sugama, H.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The structural properties of an economical model for a confined plasma turbulence governor are investigated through bifurcation and stability analyses. A close relationship is demonstrated between the underlying bifurcation framework of the model and typical behavior associated with low- to high-confinement transitions such as shear flow stabilization of turbulence and oscillatory collective action. In particular, the analysis evinces two types of discontinuous transition that are qualitatively distinct. One involves classical hysteresis, governed by viscous dissipation. The other is intrinsically oscillatory and non-hysteretic, and thus provides a model for the so-called dithering transitions that are frequently observed. This metamorphosis, or transformation, of the system dynamics is an important late side-effect of symmetry-breaking, which manifests as an unusual non-symmetric transcritical bifurcation induced by a significant shear flow drive.
description: 17 pages, revtex text, 9 figures comprised of 16 postscript files. Submitted to Phys. Rev. E
Thermodynamical Cross-Relations for Superconductors at the Critical Point
Creators: name: Grabiec, B.
name: Matlak, M.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We investigate superconducting systems with the use of the phenomenological Landau's theory of second order phase transitions, including into the considerations the critical behaviour of the chemical potential. We derive in this way a variety of new thermodynamical relations at the critical point. Twelve basic relations connect critical jumps of different thermodynamical quantites (specific heat, chemical potential derivatives with respect to temperature, pressure (volume) and number of particles, volume (pressure) derivatives with respect to temperature and pressure (volume)) with the critical temperature or its derivatives with respect to the number of particles or pressure (volume). These relations allow to find plenty of cross-relations between different quantities at the critical point. The derived formulae can practically be used in many cases to find such thermodynamical quantities at the critical point which are extremely difficult to measure under the assumption that the other ones are already known. We additionally perform a test of the two derived relations by using two-band microscopic model, describing superconducting systems. We calculate the specific heat, order parameter and chemical potential as functions of temperature to show that the tested relations are very well fulfilled.
description: phys.stat.sol. (b) 231, No. 2, 299-312 (2002)
The Tessellation-Level-Tree: characterising the nested hierarchy of density peaks and their spatial distribution in cosmological N-body simulations
Creators: name: Busch, Philipp
name: White, Simon D. M.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We use the Millennium and Millennium-II simulations to illustrate the Tessellation-Level-Tree (TLT), a hierarchical tree structure linking density peaks in a field constructed by voronoi tessellation of the particles in a cosmological N-body simulation. The TLT uniquely partitions the simulation particles into disjoint subsets, each associated with a local density peak. Each peak is a subpeak of a unique higher peak. The TLT can be persistence filtered to suppress peaks produced by discreteness noise. Thresholding a peak's particle list at $\sim 80\left$ results in a structure similar to a standard friend-of-friends halo and its subhaloes. For thresholds below $\sim 7\left$, the largest structure percolates and is much more massive than other objects. It may be considered as defining the cosmic web. For a threshold of $5\left$, it contains about half of all cosmic mass and occupies $\sim 1\%$ of all cosmic volume; a typical external point is then $\sim 7h^{-1}\mathrm{Mpc}$ from the web. We investigate the internal structure and clustering of TLT peaks. Defining the saddle point density $ρ_{\mathrm{lim}}$ as the density at which a peak joins its parent peak, we show the median value of $ρ_{\mathrm{lim}}$ for FoF-like peaks to be similar to the density threshold at percolation. Assembly bias as a function of $ρ_{\mathrm{lim}}$ is stronger than for any known internal halo property. For peaks of group mass and below, the lowest quintile in $ρ_{\mathrm{lim}}$ has $b\approx 0$, and is thus uncorrelated with the mass distribution.
description: 21 pages, 18 figures, version as accepted by MNRAS
Regional Dimensions of South Africa's CAADP Process: Lessons from West Africa
Creators: name: Haggblade, Steven
name: Staaz, John
name: Boughton, Duncan
name: Diallo, Boubacar
name: Meyer, Ferdinand
name: Minde, Issac Joseph
name: Traub, Lulama Ndibongo
name: Tschirley, David
name: Haggblade, Steven
name: Staaz, John
name: Boughton, Duncan
name: Diallo, Boubacar
name: Meyer, Ferdinand
name: Minde, Issac Joseph
name: Traub, Lulama Ndibongo
name: Tschirley, David
Publisher: name: Unknown
Year: 2015
Subjects: Agricultural and Food Policy
Agricultural Finance
International Relations/Trade

description: Regional spillovers offer prospects for accelerating Africa’s agricultural productivity growth, market development and food security. West Africa has recognised and embraced the importance of regional technology transfers, agricultural commodity trade, food security monitoring and agricultural planning. In order for the Southern African region to follow suit, South Africa’s country Comprehensive Africa Agriculture Development Programme (CAADP) plan will need to recognise the country’s critical role in enhancing regional agricultural development. An outwardlooking country vision from South Africa promises to benefit regional as well as domestic agricultural growth and food security
title: Peer to Peer Lending – A (Financial Stability) Risk Perspective
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Käfer, Benjamin
Publisher: name: Philipps-Universität Marburg
Year: 2016
Subjects: Peer-to-peer lending
financial development
Economics
Wirtschaft
financial stability risk
crowdfunding
shadow banking

description: The aim of this paper is to discuss P2P lending, a subcategory of crowdfunding, from a (financial stability) risk perspective. The discussion focuses on a number of dimensions such as the role of soft information, herding, platform default risk, liquidity risk, and the institutionalization of P2P markets. Overall, we conclude that P2P lending is more risky than traditional banking. However, it is important to recognize that a constant conclusion would be misleading. P2P platforms have evolved and changed their appearance markedly over time, which implies that although our final conclusion of increased riskiness through P2P markets remains valid over time, it is based on different arguments at different points in time. In addition, we discuss that acting on P2P online platforms satisfies most possible definitions of shadow banking and shows significant similarities with many observed aspects of shadow banking. We thus infer that P2P lending can be considered part of the shadow banking sector.
Localized Transient Jamming in Discontinuous Shear Thickening
Creators: name: Rathee, Vikram
name: Blair, Daniel L.
name: Urbach, Jeffrey S.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We report direct measurements of spatially resolved surface stresses over the entire surface of a dense suspension during discontinuous shear thickening (DST) using Boundary Stress Microscopy (BSM) in a parallel-plate rheometer. We find that large fluctuations in the bulk rheological response at the onset of DST are the result of localized transitions to a state with very high stress, consistent with a fully jammed solid that makes direct contact with the shearing boundaries. That jammed solid like phase (SLP) is rapidly fractured, producing two separate SLPs that propagate in opposite directions. By comparing the speed of propagation of the SLPs with the motion of the confining plates, we deduce that one remains in contact with the bottom boundary, and another remains in contact with the top. These regions grow, bifurcate, and eventually interact and decay in a complex manner that depends on the measurement conditions (constant shear rate vs constant stress). In constant applied stress mode, BSM directly reveals dramatic stress fluctuations that are completely missed in standard bulk rheology.
HEMATOLOGICAL PARAMETERS OF CHICKENS FED BY CLOVER YELLOW
Creators: name: Chudak R.А.
Publisher: name: Colloquium-journal
Year: 2021
Subjects: replacement young
Lohmann brown
erythrocytes
leukocytes
leukocyte formula
biochemical composition of blood
yellow clover.

description: The article includes research results on the morphological and biochemical blood parameters of the Lohmann Brown breed chickens fed by rations enriched with a new biologically active supplement of yellow clover during the growing period.
Spectral and dynamical properties of disordered and noisy quantum spin models
Creators: name: Rowlands, Daniel Alexander
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: condensed matter theory
many-body physics
quantum spin models
disorder
localisation
random matrix theory

description: This thesis, divided into two parts, is concerned with the analysis of spectral and dynamical characteristics of certain quantum spin systems in the presence of either I) quenched disorder, or II) dynamical noise. In the first part, the quantum random energy model (QREM), a mean-field spin glass model with a many-body localisation transition, is studied. In Chapter 2, we attempt a diagrammatic perturbative analysis of the QREM from the ergodic side, proceeding by analogy to the single-particle theory of weak localisation. Whilst we are able to describe diffusion, the analogy breaks down and a description of the onset of localisation in terms of quantum corrections quickly becomes intractable. Some progress is possible by deriving a quantum kinetic equation, namely the relaxation of the one-spin reduced density matrix is determined, but this affords little insight and extension to two-spin quantities is difficult. We change our approach in Chapter 3, studying instead a stroboscopic version of the model using the formalism of quantum graphs. Here, an analytic evaluation of the form factor in the diagonal approximation is possible, which we find to be consistent with the universal random matrix theory (RMT) result in the ergodic regime. In Chapter 4, we replace the QREM’s transverse field with a random kinetic term and present a diagrammatic calculation of the average density of states, exact in the large-N limit, and interpret the result in terms of the addition of freely independent random variables. In the second part, we turn our attention to noisy quantum spins. Chapter 5 is concerned with noninteracting spins coupled to a common stochastic field; correlations arising from the common noise relax only due to the spins’ differing precession frequencies. Our key result is a mapping of the equation of motion of n-spin correlators onto the (integrable) non-Hermitian Richardson-Gaudin model, enabling exact calculation of the relaxation rate of correlations. The second problem, addressed in Chapter 6, is that of the dynamics of operator moments in a noisy Heisenberg model; qualitatively different behaviour is found depending on whether or not the noise conserves a component of spin. In the case of nonconserving noise, we report that the evolution of the second moment maps onto the Fredrickson-Andersen model – a kinetically constrained model originally introduced to describe the glass transition. This facilitates a rigorous study of operator spreading in a continuous-time model, providing a complementary viewpoint to recent investigations of random unitary circuits.
description: EPSRC
Deconfined, Massive Quark Phase at High Density and Compact Stars: A Holographic Study
Creators: name: Fadafan, Kazem Bitaghsir
name: Rojas, Jesus Cruz
name: Evans, Nick
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: In Hoyos et al. (arXiv:1603.02943) a holographic D3/D7 system was used to describe a deconfined yet massive quark phase of QCD at finite density, concluding that the equation of state of such a phase was not stiff enough to support exotic dense stars. That analysis used a hard quark mass to represent the dynamical mass and assumed a conformal gauge background. Here we phenomenologically adjust the D3/D7 system to include a running anomalous dimension for the quark condensate. This introduces a dynamical mechanism for chiral symmetry breaking yet the model still has a deconfined massive phase at intermediate densities. We show that these systems, dependent on the running profile in the deep IR, generate much stiffer equations of state and non-monotonic behaviour in the speed of sound. The results suggest that these equations of state may be closer to supporting hybrid stars with quark cores.
description: 13 pages, 16 figures, added discussion
Microscopic theory of in-plane critical field in two-dimensional Ising superconducting systems
Creators: name: Liu, Hongchao
name: Liu, Haiwen
name: Zhang, Ding
name: Xie, X. C.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We study the in-plane critical magnetic field of two-dimensional Ising superconducting systems, and propose the microscopic theory for these systems with or without inversion symmetry. Protected by certain specific spin-orbit interaction which polarizes the electron spin to the out-of-plane direction, the in-plane critical fields largely surpass the Pauli limit and show remarkable upturn in the zero temperature limit. The impurity scattering and Rashba spin-orbit coupling, treated on equal-footing in the microscopic framework, both weaken the critical field but in qualitatively different manners. The microscopic theory is consistent with recent experimental results in stanene and Pb superconducting ultra-thin films.
From Fault Dynamics to Seismic Hazard Assessment
Creators: name: MICHEL, Sylvain
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: Fault Dynamics
Seismic Hazard
Parkfield
Cascadia
Gorkha earthquake
Moment Budget
Partial rupture
Slow slip events

description: My work focused on the development of improved methodologies for the evaluation of seismic hazard and its related uncertainties, based on the study of active faults systems and dynamic modelling of the seismic cycle. I worked in particular on the probabilistic estimate of a fault‘s maximum magnitude earthquake and of its return period. Those parameters are indeed crucial to estimate seismic hazard. Seismicity can be viewed as a stochastic process which is constrained by the principle of moment conservation: seismic ruptures must in principle rupture fault portions which had accumulated a deficit of slip, in view of their long term slip rate, during the interseismic period. In Chapter 1, I explain how we implemented those constraints in the evaluation of the probability distribution describing the magnitude and return period of the largest earthquake, propagating the geodetic uncertainties up to the hazard calculation. We applied this methodology to the Parkfield Segment of the San Andreas Fault, where the seismic cycle is particularly well documented. Our study implies potential maximum magnitude between 6.5 and 7.5, with a return period of 140 to 300 years. In Chapter 2, we applied the same methodology to the Cascadia subduction zone, known to have produced a M~9 earthquake in 1700 but where the seismic hazard remains poorly constrained. As part of this study we determined a model of interseismic coupling and of fault slip due to Slow Slip Events using an Independent Component Analysis-based inversion method. Finally, in Chapter 3, I use dynamic modelling to tackle the problem of partial ruptures. Large earthquakes tend to be confined to fault areas locked in the interseismic period but they often rupture them only partially. For example, during the 2015 M7.8 Gorkha earthquake, Nepal, a slip pulse propagating along-strike unzipped the bottom edge of the locked portion of the Main Himalayan Thrust. The lower edge of the rupture produced dominant high-frequency (>1 Hz) radiation of seismic waves. We showed that similar partial ruptures occur spontaneously in a simple dynamic model of earthquake sequences on a planar fault without mechanical, frictional and geometrical heterogeneities.
Matrix dynamics of fuzzy spheres
Creators: name: Jatkar, Dileep P.
name: Mandal, Gautam
name: Wadia, Spenta R.
name: Yogendran, K. P.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the dynamics of fuzzy two-spheres in a matrix model which represents string theory in the presence of RR flux. We analyze the stability of known static solutions of such a theory which contain commuting matrices and SU(2) representations. We find that irreducible as well as reducible representations are stable. Since the latter are of higher energy, this stability poses a puzzle. We resolve this puzzle by noting that reducible representations have marginal directions corresponding to non-spherical deformations. We obtain new static solutions by turning on these marginal deformations. These solutions now have instability or tachyonic directions. We discuss condensation of these tachyons which correspond to classical trajectories interpolating from multiple, small fuzzy spheres to a single, large sphere. We briefly discuss spatially independent configurations of a D3/D5 system described by the same matrix model which now possesses a supergravity dual.
description: 26 pages, 3 figures, uses JHEP.cls; (v2) references added
Metal Mediated Mechanisms of Drug Release
Creators: name: Stenton, Benjamin James
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: Bioorthogonal
decaging
linker
ADC
antibody-drug conjugate
targeted drug delivery
drug delivery
bifunctional linker
protein modification
organometallic
catalysis
chemotherapy
cancer
bioconjugation
conjugation

description: In this thesis will be described research towards the development of bioorthogonal bond-cleavage reactions, and their applications in targeted drug delivery (Figure 1). The first project relates to the development of a palladium mediated bond-cleavage or “decaging” reaction which can cause a propargyl carbamate to decompose and release an amine. This was further developed by the incorporation of a protein modification handle which allowed an amine-bearing drug to be covalently ligated to a protein by a palladium-cleavable linker. This chemistry was demonstrated by the conjugation of the anticancer drug doxorubicin to a tumour targeted anti-HER2 nanobody. The drug could then be delivered to cancer cells upon addition of a palladium complex. The second project relates to the development of a platinum mediated bond-cleavage reaction. This was developed with the aim of using platinum-containing anticancer drugs – such as cisplatin – as a catalyst to cause drug release reactions in tumours. In this reaction an alkyne-containing amide can decompose to release an amine upon addition of platinum complexes, and was applied to the release of prodrugs of the cytotoxins monomethylauristatin E and 5-fluorouracil in cancer cells. A cisplatin-cleavable antibody-drug conjugate was designed and synthesised, and progress towards its biological evaluation will be discussed.
description: EPSRC
title: Exhaustion of Digital Goods: An Economic Perspective
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Kerber, Wolfgang
Publisher: name: Philipps-Universität Marburg
Year: 2016
Subjects: copyright exhaustion
post-sale restrictions
Digital goods
Economics
Wirtschaft
first-sale doctrine

description: The "UsedSoft" decision of the Court of Justice of the European Union (CJEU)
about the right of a buyer of a downloaded copy of a software to resell this copy triggered a controversial discussion about the applicability of the "exhaustion" rule (US: first-sale doctrine) to copyright-protected digital goods (as, e.g., also e-books). This paper offers, in a first step, a systematic analysis and assessment of economic reasonings that have been discussed in the literature about exhaustion, and applies this framework, in a second step, to downloaded digital creative works. An important result is that digitalisation, on one hand, changes considerably the benefits and costs of exhaustion, esp. in regard to the danger of jeopardizing the incentives for copyright owners. On the other hand, however, also the costs of imposing restrictions might be high and even increase in a digital economy. This leads to the conclusion that it is necessary to think seriously about the legal limits for the restrictions that copyright owners should be allowed to impose on their customers. However, these limits might be drawn also by other legal instruments than copyright exhaustion.
Horizon- Scanning the Ostrich Industry with Bibliometric Indicators
Creators: name: Pittaway, Timothy
name: Niekerk, Pieter Van
name: Pittaway, Timothy
name: Niekerk, Pieter Van
Publisher: name: Unknown
Year: 2015
Subjects: Agricultural and Food Policy
International Relations/Trade
Livestock Production/Industries

description: Regional spillovers offer prospects for accelerating Africa’s agricultural productivity growth, market development and food security. West Africa has recognised and embraced the importance of regional technology transfers, agricultural commodity trade, food security monitoring and agricultural planning. In order for the Southern African region to follow suit, South Africa’s country Comprehensive Africa Agriculture Development Programme (CAADP) plan will need to recognise the country’s critical role in enhancing regional agricultural development. An outwardlooking country vision from South Africa promises to benefit regional as well as domestic agricultural growth and food security
title: Algorithmic and High-Frequency Trading Strategies: A Literature Review
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Mandes, Alexandru
Publisher: name: Philipps-Universität Marburg
Year: 2016
Subjects: high-frequency trading
electronic market making
algorithmic trading
Economics
Wirtschaft

description: The advances in computer and communication technologies have
created new opportunities for improving, extending the application of or
even developing new trading strategies. Transformations have been observed
both at the level of investment decisions, as well as at the order execution
layer. This review paper describes how traditional market participants, such
as market-makers and order anticipators, have been reshaped and how new
trading techniques relying on ultra-low-latency competitive advantage, such
as electronic \front running", function. Also, the natural con
ict between liquidity-consumers and liquidity-suppliers has been taken to another level, due to the proliferation of algorithmic trading and electronic liquidity provision
strategies.
Global existence of strong solutions to a groundwater flow problem
Creators: name: Xu, Xiangsheng
Publisher: name: arXiv
Year: 2019
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In this paper we study the initial boundary value problem for the system $Δv= u_{x_1},\ u_t-\mbox{div}\left(\left((a|\mathbf{q}|+m)I+(b-a)\frac{\mathbf{q}\otimes\mathbf{q}}{|\mathbf{q}|}\right)\nabla u\right)=-\nabla u\cdot\mathbf{q}$, where $\mathbf{q}=(-v_{x_2}, v_{x_1})^T$, $\mathbf{q}\otimes\mathbf{q}=\mathbf{q}\mathbf{q}^T$. This problem has been proposed as a model for a fluid flowing through a porous medium under the influence of gravity and hydrodynamic dispersion. For each $T>0$ we obtain a so-called strong solution $(v, u)$ in the function space $L^\infty(0,T; \left(W^{1,\infty}(Ω)\right)^2)$, where $Ω$ is a bounded domain in $\mathbb{R}^2$. The key ingredient in our approach is the decomposition $A^2=\mbox{tr} (A)A-\mbox{det}(A) I$ for any $2\times 2$ symmetric matrix $A$. By exploring this decomposition, we are able to derive an equation of parabolic type for the function $\left(\left((a|\mathbf{q}|+m)I+(b-a)\frac{\mathbf{q}\otimes\mathbf{q}}{|\mathbf{q}|}\right)\nabla u\cdot\nabla u\right)^j, j\geq 1$. With the aid of this equation we obtain a uniform bound for $\nabla u$.
On Degrees of Freedom of Projection Estimators With Applications to Multivariate Nonparametric Regression
Creators: name: Chen, Xi
name: Lin, Qihang
name: Bodhisattva Sen
Publisher: name: Taylor & Francis
Year: 2019
Subjects: Medicine
Neuroscience
Pharmacology
Biotechnology

description: Abstract–In this article, we consider the nonparametric regression problem with multivariate predictors. We provide a characterization of the degrees of freedom and divergence for estimators of the unknown regression function, which are obtained as outputs of linearly constrained quadratic optimization procedures; namely, minimizers of the least-squares criterion with linear constraints and/or quadratic penalties. As special cases of our results, we derive explicit expressions for the degrees of freedom in many nonparametric regression problems, for example, bounded isotonic regression, multivariate (penalized) convex regression, and additive total variation regularization. Our theory also yields, as special cases, known results on the degrees of freedom of many well-studied estimators in the statistics literature, such as ridge regression, Lasso and generalized Lasso. Our results can be readily used to choose the tuning parameter(s) involved in the estimation procedure by minimizing the Stein’s unbiased risk estimate. As a by-product of our analysis we derive an interesting connection between bounded isotonic regression and isotonic regression on a general partially ordered set, which is of independent interest. Supplementary materials for this article are available online.
Search for electroweak production of charginos and sleptons decaying into final states with two leptons and missing transverse momentum in $\sqrt{s}=13$ TeV $pp$ collisions using the ATLAS detector
Creators: name: ATLAS Collaboration
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for the electroweak production of charginos and sleptons decaying into final states with two electrons or muons is presented. The analysis is based on 139 fb$^{-1}$ of proton-proton collisions recorded by the ATLAS detector at the Large Hadron Collider at $\sqrt{s}=13$ TeV. Three $R$-parity-conserving scenarios where the lightest neutralino is the lightest supersymmetric particle are considered: the production of chargino pairs with decays via either $W$ bosons or sleptons, and the direct production of slepton pairs. The analysis is optimised for the first of these scenarios, but the results are also interpreted in the others. No significant deviations from the Standard Model expectations are observed and limits at 95 % confidence level are set on the masses of relevant supersymmetric particles in each of the scenarios. For a massless lightest neutralino, masses up to 420 GeV are excluded for the production of the lightest-chargino pairs assuming $W$-boson-mediated decays and up to 1 TeV for slepton-mediated decays, whereas for slepton-pair production masses up to 700 GeV are excluded assuming three generations of mass-degenerate sleptons.
description: 30 pages plus author list (47 pages total), 8 figures, 9 tables, All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/SUSY-2018-32
PHOTOSYNTHETIC ACTIVITY AND YIELD OF SAFFLOWER UNDER THE INFLUENCE OF ADDITIONAL NUTRITION
Creators: name: Poliakov О. І.
name: Aliieva O. Yu.
Publisher: name: Colloquium-journal
Year: 2021
Subjects: safflower
mineral fertilizer
growth regulator
photosynthetic activity
net photosynthesis productivity
yield.

description: Article presents the main results of research for 2017–2019, the purpose of which was to establish the impact of using mineral fertilizers and growth regulators on photosynthetic activity and yield of safflower in the Southern Steppe of Ukraine. It was established that the highest rates of NPF were observed during the floweringmaturity period: 4.55–4.89 g/m2/day for Zhyvchyk variety and 4.32–4.49 g/m2/day for Dobrynya variety. Highest yields of Zhyvchyk safflower variety – 1.71 t/ha and 1.70 t/ha and Dobrynya variety – 1.84 t/ha and 1.85 t/ha were obtained when using mineral fertilizers at N60P50 dose with main tillage and use of Rost–concentrate + Chelatin oil and Chelatin mono boron + Chelatin phosphorus–potassium.
title: Standing and “Survival” in the Adult Film Industry
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Lüdering, Jochen
Publisher: name: Philipps-Universität Marburg
Year: 2016
Subjects: Economics
Wirtschaft
Social Capital
Centrality
Network Analysis
Duration Analysis
Professional Success

description: It is said that knowing the right people is essential for one’s career, which is supported in the literature on social capital. However, the empirical evidence in this field remains ambiguous, while the literature recognizes that “connections” certainly help finding any job at all, it remains unclear if there is a long-term benefit. While it is difficult to record a network structure in most industries, in the adult film industry collaboration between performers is easily observed. Consequently, a collaborative network can be constructed for which centrality measures can be calculated in order to estimate the effect on success. Unfortunately, success is not easily observed either. Hence, in this manuscript, the survival in the industry is used as a proxy for professional success. This assumption is justified by the economic argument that, in the absence of lock-in effects, performers will remain in the industry as long as it remains profitable. The profitability will not only depend on monetary aspects, but, in addition to economic costs, it takes potential costs from loss of reputation and personal well-being into account. The research at hand stands stands out by pioneering the use of centrality measures in duration models which, to the best of my knowledge, is a novel approach in the field. The results indicate that there is a strong correlation between network centrality and industry survival for the adult film industry.
Lyman Alpha Intensity Mapping via Grism Spectrotomography
Creators: name: Zhonghao Luo
Publisher: name: Carnegie Mellon University
Year: 2019
Subjects: subject: 20399 Classical Physics not elsewhere classified
subject: FOS: Physical sciences

description: The discovery of cosmic acceleration implies that universe is dominated by some form of \dark energy" that causes repulsive gravity. This accelerated expansion of the universe can be probed by Baryon Acoustic Oscillations (BAO). BAO is a well developed method to measure the expansion history and the structure growth of the universe. Intensity mapping is a new observation technique that can probe BAO
and large scale structures. A new type of telescope, the Grism Spectrotomographic Imager (GSTI), is described in the thesis. The GSTI is designed for Lyman Alpha
(Ly ) intensity mapping. A grism, the combination of grating and prism, is placed in front of a camera to disperse the light of each point on the sky into a spectrum and
shift the spectrum back closer to the original image point. Images are taken as the grism rotates about the optical axis, resulting in a set of grism-dispersed images with
diff erent spectra orientations. A hyperspectral data cube is then reconstructed from this set of grism-dispersed images through back projection and point spread function
(PSF) deconvolution. The Richardson-Lucy method is chosen as the deconvolution algorithm in the thesis due to its speed and performance. In contrast to other wide
 eld spectroscopy techniques, Grism Spectrotomography collects all available photons simultaneously and e fficiently yields the spectrum of each sky pixel within the field
of view. It has high throughput and a multiplex advantage. A prototype GSTI was built, and the data acquisition pipeline was developed for the telescope. GSTI was tested in the lab and on the sky. Reconstruction results show that GSTI is
capable of simultaneously providing spectra of multiple sources in the fi eld. The star foreground was also carefully studied for intensity mapping. Masking of Milky Way stars is required for cosmological Lya intensity mapping because bright stars can a ffect the detection and the power spectrum of Lya sources. A masking and filtering scheme is proposed to obtain a high signal-to-noise Lya power spectrum
using intensity mapping.
title: “Talking Down Monetary Policy” – A Note
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Tillmann, Peter
Publisher: name: Philipps-Universität Marburg
Year: 2016
Subjects: misperception
Economics
Wirtschaft
Optimal monetary policy
inflation
shocks
policy effectiveness

description: There is a recent debate about whether monetary policy is no longer ef-
fective in stimulating demand, a concern often voiced in the euro area. As
a response, the ECB warns against \talking down monetary policy" (ECB
Vice-President Vitor Constancio, 2016). This note uses a textbook model of optimal monetary policy to study a situation in which the public misperceives
the interest rate elasticity of aggregate demand, which reflects policy effectiveness. We show that as a result of underestimating policy effectiveness demand shocks can no longer be stabilized perfectly, thus resulting in ineffcient inflation and output dynamics. In the presence of misperceptions, a negative demand shocks leads to a prolonged period of negative in
ation rates.
PREPARATION STRATEGIES FOR THE SECTION “WRITING” OF THE RUSSIAN NATIONAL EXAM
Creators: name: Lymareva Natalia
Publisher: name: Colloquium-journal
Year: 2021
Subjects: writing skills
State final exam
communicative competence
narration with elements of discussion
informal letter
logic violation
cognitive abilities.

description: This article is devoted to topical issues of modern education, namely: preparing students for the English exam in section “Writing”. The article discusses the preparation strategies to the section “Writing” of State final exam. The author analyses common mistakes and offers some practical advice on preparing students for the exam.
Additional file 1: of Heat-shock protein 90α is involved in maintaining the stability of VP16 and VP16-mediated transactivation of α genes from herpes simplex virus-1
Creators: name: Wang, Yiliang
name: Wang, Rongze
name: Li, Feng
name: Wang, Yun
name: Zhang, Zhen
name: Wang, Qiaoli
name: Ren, Zhe
name: Jin, Fujun
name: Kitazato, Kaio
name: Wang, Yifei
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplemental information includes three tables and five figures. (DOCX 765 kb)
Nitrogen trifluoride - Molecule of the Month October 2019 [Archived version]
Creators: name: Cotton, Simon
Publisher: name: figshare
Year: 2019
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for October 2019 about Nitrogen trifluoride. It is a pdf archive version of the HTML webpage.
The pathological and genomic impact of CTCF depletion in mammalian model systems
Creators: name: Aitken, Sarah Jane
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: CTCF
Transcription
Hemizygosity
Cancer
Chromatin state
Chromatin architecture
Hepatocellular carcinoma
Carcinogen
Whole genome sequencing
RNA sequencing
Mutational signatures
Histopathology

description: CCCTC-binding factor (CTCF) binds DNA, thereby helping to partition the mammalian genome into discrete structural and regulatory domains. In doing so, it insulates chromatin and fine-tunes gene activation, repression, and silencing. Complete removal of CTCF from mammalian cells causes catastrophic genomic dysregulation, most likely due to widespread collapse of 3D chromatin looping within the nucleus. In contrast, Ctcf hemizygous mice with lifelong reduction in CTCF expression are viable but have an increased incidence of spontaneous multi-lineage malignancies. In addition, CTCF is mutated in many human cancers and is thus implicated as a tumour suppressor gene. This study aimed to interrogate the genome-wide consequences of a reduced genomic concentration of Ctcf and its implications for carcinogenesis. In a genetically engineered mouse model, Ctcf hemizygous cells showed modest but robust changes in almost a thousand sites of genomic CTCF occupancy; these were enriched for lower affinity binding events with weaker evolutionary conservation across the mouse lineage. Furthermore, several hundred genes concentrated in cancer-related pathways were dysregulated due to changes in transcriptional regulation. Global chromatin structure was preserved but some loop interactions were destabilised, often around differentially expressed genes and their enhancers. Importantly, these transcriptional alterations were also seen in human cancers. These findings were then examined in a hepatocyte-specific mouse model of Ctcf hemizygosity with diethylnitrosamine-induced liver tumours. Ctcf hemizygous mice had a subtle liver-specific phenotype, although the overall tumour burden in Ctcf hemizygous and wild-type mice was the same. Using whole genome sequencing, the highly reproducible mutational signature caused by DEN exposure was characterised, revealing that Braf(V637E), orthologous to BRAF(V600E) in humans, was the predominant oncogenic driver in these liver tumours. Taken together, while Ctcf loss is partially physiologically compensated, chronic CTCF depletion dysregulates gene expression by subtly altering transcriptional regulation. This study also represents the first comprehensive genome-wide and histopathological characterisation of this commonly used liver cancer model.
description: Wellcome Trust Programme for Clinicians Fellowship (106563/Z/14); EMBO|EuropaBio Fellowship (STF 7538); The Pathological Society of Great Britain & Ireland (SGS 2015/04/04); Cancer Research UK (core award 20412).