Additional file 1 of The gut microbiome modifies the associations of short- and long-term physical activity with body weight changes
Creators: name: Wang, Kai
name: Mehta, Raaj S.
name: Ma, Wenjie
name: Nguyen, Long H.
name: Wang, Dong D.
name: Ghazi, Andrew R.
name: Yan, Yan
name: Al-Shaar, Laila
name: Wang, Yiqing
name: Hang, Dong
name: Fu, Benjamin C.
name: Ogino, Shuji
name: Rimm, Eric B.
name: Hu, Frank B.
name: Carmody, Rachel N.
name: Garrett, Wendy S.
name: Sun, Qi
name: Chan, Andrew T.
name: Huttenhower, Curtis
name: Song, Mingyang
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Additional file 1: Supplementary Table 1. Characteristics of participants in the Men’s Lifestyle Validation Study according to quartiles of recent physical activity level. Supplementary Table 2. Spearman correlations between the variables of physical activity, body weight, body weight change, and plasma biomarkers. Supplementary Fig. 1. Spearman correlation between long-term total physical activity level and calorie-adjusted dietary intakes of major nutrients at p &lt; 0.05. Supplementary Fig. 2. Principal coordinate analysis of all samples using species-level Bray–Curtis dissimilarity according to recent physical activity level measured by accelerometer. Supplementary Fig. 3. Gut microbial diversity using species taxonomic data according to recent total physical activity measured by accelerometer. Supplementary Fig. 4. Significant associations of physical activity, body weight measures, and plasma biomarkers of hemoglobin A1c (HbA1c) and high-sensitivity C-reactive protein (CRP) with microbial species (q ≤ 0.25). Supplementary Fig. 5. Significant associations of physical activity, body weight measures, and plasma biomarkers of hemoglobin A1c (HbA1c) and high-sensitivity C-reactive protein (CRP) with metagenomic pathways (MetaCyc) (q ≤ 0.25). Supplementary Fig. 6. Significant associations of physical activity, body weight measures, and plasma biomarkers of hemoglobin A1c (HbA1c) and high-sensitivity C-reactive protein (CRP) with metagenomic enzymes (Enzyme Commission, EC) (q ≤ 0.25). Supplementary Fig. 7. Interaction between physical activity measures and the first two principal coordinates axis (PCo1 or PCo2) in relation to body mass index at stool collection, fat mass percentage at stool collection, short-term (6 months) weight change, long-term weight change from age 21 to stool collection, plasma hemoglobin A1c (HbA1c) and high-sensitivity C-reactive protein (CRP). Supplementary Fig. 8. Interaction between physical activity and abundances of the top 10 most abundant species in relation to body mass index at stool collection, fat mass percentage at stool collection, short-term (6 months) weight change, long-term weight change from age 21 to stool collection, plasma hemoglobin A1c (HbA1c) and high-sensitivity C-reactive protein (CRP). Supplementary Fig. 9. Associations between intensity-specific physical activity and body weight measures according to Alistipes putredinis abundance. Supplementary Fig. 10. Relative abundance, prevalence, and interactions of all the species in the genus of Alistipes with physical activity in relation to body mass index at stool collection, fat mass percentage at stool collection, short-term (6 months) weight change, long-term weight change from age 21 to stool collection, plasma hemoglobin A1c (HbA1c) and high-sensitivity C-reactive protein (CRP).