cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A potential long-range RNA-RNA interaction in the HIV-1 RNA
Creators: name: Zhou, Xia
name: Du, Zhihua
name: Huang, Xiaolan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: It is well-established that viral and cellular mRNAs alike harbour functional long-range intra-molecular RNA-RNA interactions. Despite the biological importance of such interactions, their identification and characterization remain challenging. Here we present a computational method for the identification of certain kinds of long-range intra-molecular RNA-RNA interactions involving the loop nucleotides of a hairpin loop. Using the computational method, we analysed 4272 HIV-1 genomic mRNAs. A potential long-range intra-molecular RNA-RNA interaction within the HIV-1 genomic RNA was identified. The long-range interaction is mediated by a kissing loop structure between two stem-loops of the previously reported SHAPE-based secondary structure of the entire HIV-1 genome. Structural modelling studies were carried out to show that the kissing loop structure not only is sterically feasible, but also contains a conserved RNA structural motif often found in compact RNA pseudoknots. The computational method should be generally applicable to the identification of potential long-range intra-molecular RNA-RNA interactions in any viral or cellular mRNA sequence. Communicated by Ramaswamy H. Sarma
Neutron structure function $F_2^n(x)$ from deep inelastic electron scattering off few-nucleon systems
Creators: name: Pace, E.
name: Salme`, G.
name: Scopetta, S.
name: Kievsky, A.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The possibility of a reliable extraction of the neutron deep inelastic structure function, $F_2^n(x)$, for $ x < 0.85$ from joint measurements of deep inelastic structure functions of deuteron, $^{3}He$ and $^{3}H$ is investigated. The model dependence in this extraction, linked to the possible different interactions between nucleons in nuclei, is shown to be weak, if the nuclear structure effects are properly taken into account. A combined analysis of the deep inelastic structure functions of these nuclei is proposed to study effects beyond the impulse approximation.
description: Phys. Rev. C in press
Additional file 2 of All-cause mortality and cardiovascular events in a Spanish nonagenarian cohort according to type 2 diabetes mellitus status and established cardiovascular disease
Creators: name: Salinero-Fort, MA
name: Mostaza, J.
name: Lahoz, C.
name: Cárdenas-Valladolid, J.
name: Vicente-Díez, J. I.
name: Gómez-Campelo, P.
name: de Miguel-Yanes, J. M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 2.
Evidence from 3-month-old infants shows that a combination of postnatal feeding and exposures in utero shape lipid metabolism
Creators: name: Furse, Samuel
name: Snowden, Stuart G.
name: Olga, Laurentya
name: Prentice, Philippa
name: Ong, Ken K.
name: Hughes, Ieuan A.
name: Acerini, Carlo L.
name: Dunger, David B.
name: Koulman, Albert
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Article
/631/92/608
/692/53/2422
/692/699/2743/137/1926
article

description: Abstract: We tested the hypothesis that both postnatal feeding and conditions in utero affect lipid metabolism in infants. Infants who experienced restrictive growth conditions in utero and others exposed to maternal hyperglycaemia were compared to a control group with respect to feeding mode. Dried blood spots were collected from a pilot subset of infant participants of the Cambridge Baby Growth Study at 3mo. Groups: (a) a normal gestation (control, n = 40), (b) small for gestational age (SGA, n = 34) and (c) whose mothers developed hyperglycaemia (n = 59). These groups were further stratified by feeding mode; breastfed, formula-fed or received a mixed intake. Their phospholipid, glyceride and sterol fractions were profiled using direct infusion mass spectrometry. Statistical tests were used to identify molecular species that indicated differences in lipid metabolism. The abundance of several phospholipids identified by multivariate analysis, PC(34:1), PC(34:2) and PC-O(34:1), was 30–100% higher across all experimental groups. SM(39:1) was around half as abundant in in utero groups among breastfed infants only. The evidence from this pilot study shows that phospholipid metabolism is modulated by both conditions in utero and postnatal feeding in a cohort of 133 Caucasian infants, three months post partum.
Additional file 3 of All-cause mortality and cardiovascular events in a Spanish nonagenarian cohort according to type 2 diabetes mellitus status and established cardiovascular disease
Creators: name: Salinero-Fort, MA
name: Mostaza, J.
name: Lahoz, C.
name: Cárdenas-Valladolid, J.
name: Vicente-Díez, J. I.
name: Gómez-Campelo, P.
name: de Miguel-Yanes, J. M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 3.
Mixed Reality-based Process Control of Automatic Printed Circuit Board Assembly Lines
Creators: name: Hahn, Jürgen
name: Ludwig, Bernd
name: Wolff, Christian
Publisher: name: Universität Regensburg
Year: 2018
Subjects: subject: 004 Informatik

description: A mixed reality (MR)-based concept for supporting and optimizing the way operators work with automatic printed circuit board (PCB) assembly lines, is proposed. In order to enhance the work process’ interface, users are outfitted with a head-mounted display (HMD), so they can both actively access process relevant machine data and passively receive system notifications in a heads-up display (HUD), instead of having to manually query the terminal of the machine of interest at its very location. This approach was implemented and tested in a field study with one of the assembly lines of an electronics manufacturing services (EMS)-company. 30 staff members were recruited as test subjects and 90% of them appreciated the system deployment, due to its noticeable additional benefits compared to the status quo.
Untitled Item
Creators: name: Monteiro, Maria Helena Durães Alves
name: Macedo, Heloísa Werneck De
name: Arley Da Silva Junior
name: Paumgartten, Francisco José Roma
Publisher: name: figshare
Year: 2019
Subjects: subject: Botany
subject: 110499 Complementary and Alternative Medicine not elsewhere classified
subject: FOS: Clinical medicine

description: As espécies de Melaleuca L. (Myrtaceae) são importantes plantas medicinais e aromáticas, muitas das quais produtoras de óleos essenciais utilizados na indústria de cosméticos e produtos farmacêuticos em todo o mundo. Os óleos essenciais obtidos de diferentes representantes desse gênero são ricos em mono e sesquiterpenos e suas atividades farmacológicas têm sido amplamente estudadas. No entanto, as indicações clínicas não são abordadas na maioria das revisões desse grupo e mantêm-se restritas às Farmacopéias. A presente revisão tem como objetivo resumir as principais informações sobre a caracterização botânica, a fitoquímica, a farmacologia, a toxicologia e a aplicação clínica dos principais óleos essenciais obtidos de Melaleuca com potencial utilização na prática clínica.
Is the Role of Irrigation in Agricultural Output Declining in India?: A District-Wise Study at Six Time Points
Creators: name: Narayanamoorthy, A.
name: Alli, P.
name: Suresh, R.
name: Narayanamoorthy, A.
name: Alli, P.
name: Suresh, R.
Publisher: name: Unknown
Year: 2015
Subjects: subject: Crop Production/Industries
subject: Land Economics/Use
subject: Farm profitability
subject: Irrigated area and crops
subject: Rainfed crops
subject: Value of agricultural output

description: The significant role of irrigation development in land use pattern, cropping pattern, cropping intensity, production and productivity of crops has been well documented by various studies in India. However, the contributions of irrigation to agricultural output and related parameters are fervently questioned in the recent years. Since the role of irrigation in increasing the value of agricultural output has not been studied by many scholars especially using disaggregated data covering different time points, an attempt has been made in this study to fill this gap by using cross-sectional data for 235 Indian districts, drawn from 13 states at six time points: 1962-65, 1970-73, 1980-83, 1990-93, 2003-05 and 2005-08. Both descriptive and regression analyses have been carried out to study the relationship. Descriptive analysis shows that the difference in value of agricultural output per hectare has narrowed down between less (<30 per cent), medium (30-50 per cent) and high (>50 per cent) irrigated districts over the years, especially after 1990-93. The univariate regression analysis carried out treating irrigation (with and without dummy as well as with and without time lag) as an independent variable and the value of agricultural output per hectare as dependent variable shows that the impact of irrigation on the value of output has declined (both irrigation coefficient and R2) over time. During 1980-83 and 1990-93, irrigation alone has explained around 50 per cent of variation in agricultural output, but the same declined to about 24 per cent during 2003-05 and 2005-08. Multivariate regression analysis carried out by using different yield increasing and infrastructure variables suggests that although irrigation still plays a dominant role in increasing the value of output, its value of coefficients has been declining over time. Although both univariate and multivariate regression results show a declining trend of irrigation coefficient over time, one may not be able to firmly say that the role of irrigation in determining the value of agricultural output has reduced over time, as this could have happened due to acceleration in the productivity of crops cultivated in the rainfed/less irrigated districts.
The Influence of User Interface Attributes on Aesthetics
Creators: name: Schmidt, Thomas
name: Wolff, Christian
Publisher: name: Universität Regensburg
Year: 2018
Subjects: subject: Aesthetics, user interface design, website design, symmetry, visual complexity, colorfulness
subject: 004 Informatik
subject: 150 Psychologie
subject: 700 Künste, Bildende Kunst allgemein

description: In this paper we present an empirical study among 40 participants which investigates the relationship between various factors of user interface aesthetics on the one hand, and the influence of the user interface attributes, symmetry, colorfulness as well as visual complexity on user interface aesthetics on the other hand. The user interface aesthetics will be classified in intuitive aesthetics (1st impression with a presentation time of 500 ms) and reflective aesthetics (reflective long-term impression after a longer presentation). Reflective aesthetics is further classified in classical aesthetics (common attractiveness) as well as expressive aesthetics (creativity). For this study we have set up a corpus of 30 websites which are used as stimulus material. In a multi-step lab experiment, participants rate aesthetics and their subjective impression concerning user interface attributes using questionnaires. We are able to show that the intuitive aesthetic judgment correlates strongly with the reflective judgment. The symmetry of a website positively correlates with all definitions of aesthetics, especially with the classical or traditional interpretation in the sense of attractiveness. Visual complexity can be seen as the strongest predictor for the aesthetic judgement of users and it negatively correlates with all definitions. Concerning colorfulness, a preference for websites of a medium degree of colorfulness for the intuitive as well as the classical aesthetics can be stated. Concerning expressive aesthetics, websites of moderate to high colorfulness receive the best judgments. The relationships which we have found are finally discussed in the context of previous research and some implications for future user interface design are given.
An Economic Analysis to Determine the Feasibility of Groundwater Supplementation from the Dockum Aquifer
Creators: name: Mitchell, Donna M.
name: Williams, Ryan Blake
name: Johnson, Phillip
name: Mitchell, Donna M.
name: Williams, Ryan Blake
name: Johnson, Phillip
Publisher: name: Unknown
Year: 2016
Subjects: subject: Environmental Economics and Policy
subject: Farm Management
subject: Production Economics
subject: Resource /Energy Economics and Policy
subject: Dockum
subject: optimization

description: As water resources from the Ogallala Aquifer continue to decline, alternative sources of water resources should be considered to extend the life of irrigated agriculture in the Southern High Plains. The Dockum is a minor aquifer located beneath the Ogallala at depths of up to 2,000 feet. The Dockum Aquifer may be a suitable water source for irrigation supplementation; however, the cost to pump from the Dockum may not be economically profitable due to deep pumping depths, poor water quality, and low well yields. Results show that in some areas of the Dockum, it may complement irrigation water from the Ogallala for water thirsty crops.
Additional file 4 of All-cause mortality and cardiovascular events in a Spanish nonagenarian cohort according to type 2 diabetes mellitus status and established cardiovascular disease
Creators: name: Salinero-Fort, MA
name: Mostaza, J.
name: Lahoz, C.
name: Cárdenas-Valladolid, J.
name: Vicente-Díez, J. I.
name: Gómez-Campelo, P.
name: de Miguel-Yanes, J. M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 4.
(Super-)integrable systems associated to 2-dimensional projective connections with one projective symmetry
Creators: name: Manno, Gianni
name: Vollmer, Andreas
Publisher: name: arXiv
Year: 2019
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53A20, 53B10

description: Projective connections arise from equivalence classes of affine connections under the reparametrization of geodesics. They may also be viewed as quotient systems of the classical geodesic equation. After studying the link between integrals of the (classical) geodesic flow and its associated projective connection, we turn our attention to 2-dimensional metrics that admit one projective vector field, i.e. whose local flow sends unparametrized geodesics into unparametrized geodesics. We review and discuss the classification of these metrics, introducing special coordinates on the linear space of solutions to a certain system of partial differential equations, from which such metrics are obtained. Particularly, we discuss those that give rise to free second-order superintegrable Hamiltonian systems, i.e. which admit 2 additional, functionally independent quadratic integrals. We prove that these systems are parametrized by the 2-sphere, except for 6 exceptional points where the projective symmetry becomes homothetic.
description: 23 pages, 5 tables
How far has Africa gone in achieving Sustainable Development Goals? Exploring African Dataset
Creators: name: Otekunrin, Olutosin
name: Otekunrin, Oluwaseun
name: Siaka Momoh
name: Ayinde, Idris A.
Publisher: name: figshare
Year: 2019
Subjects: subject: 70108 Sustainable Agricultural Development
subject: FOS: Other agricultural sciences

description: The dataset describes the status of African countries on the attainment of Sustainable Development Goals (SDGs). Datasets on SDG Index (SDGI) scores and other selected variables were compiled from relevant secondary sources. Graphical illustrations were used to describe the type of association existing between the SDGI scores and each of the selected variables to corroborate [1]. Further rigorous statistical analysis can be carried out using these data, in conjunction with other datasets to establish scientifically proven cause and effect relationships among the variables.
Introduction of water-vapor broadening coefficients and their temperature dependence exponents into the HITRAN database, Part I: CO2, N2O, CO, CH4, O2, NH3, and H2S
Creators: name: Tan, Yan
name: Kochanov, Roman V.
name: Rothman, Laurence S.
name: Gordon, Iouli E.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The amount of water vapor in the terrestrial atmosphere is highly variable both spatially and temporally. In the tropics it sometimes constitutes 4-5% of the atmosphere. At the same time collisional broadening of spectral lines by water vapor is much larger than that by nitrogen and oxygen. Therefore, in order to accurately characterize and model spectra of the atmospheres with significant amounts of water vapor, the line-shape parameters for spectral lines broadened by water vapor are required. In this work, the line-broadening coefficients (and their temperature dependence exponents) due to the pressure of water vapor for lines of CO2, N2O, CO, CH4, O2, NH3, and H2S from both experimental and theoretical studies were collected and carefully reviewed. A set of semi-empirical models based on these collected data was created and then used to estimate water broadening and its temperature dependence for all transitions of selected molecules in the HITRAN2016 database.
description: Submitted to the Journal of Geophysical Research: Atmospheres on May 23, 2019. 3 Tables, 11 Figures
Katharsis – A Tool for Computational Drametrics
Creators: name: Schmidt, Thomas
name: Burghardt, Manuel
name: Dennerlein, Katrin
name: Wolff, Christian
Publisher: name: Universität Regensburg
Year: 2019
Subjects: subject: Drametrics, Distant Reading, Computational Literary Studies, Drama Analysis, Statistics, Tool, Visualization
subject: 004 Informatik
subject: 020 Bibliotheks- und Informationswissenschaft
subject: 400 Sprachwissenschaft, Linguistik
subject: 800 Literatur, Rhetorik, Literaturwissenschaft
subject: 830 Deutsche Literatur

description: We present Katharsis, a tool for "computational drametrics" that implements Solomon Marcus' (1973) theory of mathematical drama analysis. The tool computes and visualizes character configurations and speech statistics for different levels of analysis and allows users to compare different collections of plays. We illustrate the usefulness of the tool for literary studies via several use cases. The tool is freely available online for a test corpus of approximately 100 German plays: http://lauchblatt.github.io/Katharsis/index.html
Antarctobius vulsus
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Antarctobius
Antarctobius vulsus

description: Antarctobius vulsus (Enderlein, 1907)
 Listroderes vulsus Enderlein, 1907: 50 (type locality: Argentina: Falkland Islands (Islas Malvinas), Port Darwin, Goosegreen; type material: S: NHRS).
 Listroderes gibber Enderlein, 1907: 51 (type locality: Argentina: Falkland Islands (Islas Malvinas), Port William, Sparrow Cove; type material: S: NHRS); Kuschel, 1950: 13 (= L. vulsus).
 Listroderes griseonotatus Champion, 1918a: 179 (type locality: Argentina: Falkland Islands (Islas Malvinas); type material: H: BMNH); Kuschel, 1955: 289 (= L. vulsus).
 Antarctobius vulsus; Morrone, 1992a: 8.
 Distribution. Falkland Islands (Islas Malvinas) (Morrone, 1992a; Posadas, 2008).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 16, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Influence of nuclear spin polarization on spin echo signal of NV center qubit
Creators: name: Kwiatkowski, Damian
name: Szańkowski, Piotr
name: Cywiński, Łukasz
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We consider the spin echo dynamics of a nitrogen-vacancy center qubit based the $S\!= \! 1$ ground state spin manifold, caused by a dynamically polarized nuclear environment. We show that the echo signal acquires then a nontrivially time-dependent phase shift. This effect should be observable for polarization $\approx \! 0.5$ of nuclei within $\sim \! 1$ nm from the qubit, and for the NV center initialized in a superposition of $m\! = \! 0$ and either $m\! =\! 1$ or $m\! =\! -1$ states. This phase shift is much smaller when the NV center is prepared in a superposition of $m\! = \! 1$ and $m\! =\! -1$ states, i.e. when the qubit couples to the spin environment in a way analogous to that of spin-$1/2$. For nuclear environment devoid of spins strongly coupled to the qubit, the phase shift is well described within Gaussian approximation, which provides an explanation for the dependence of the shift magnitude on the choice of states on which the qubit is based, and makes it clear that its presence is related to the linear response of the environment perturbed by an evolving qubit. Consequently, its observation signifies the presence environment-mediated self-interaction of the qubit, and hence, it invalidates the notion that the nuclear environment acts as a source of external noise driving the qubit. We also show how a careful comparison of the echo signal from qubits based on $m\! = \! 0,1$ and $m\! =\! \pm 1$ manifolds, can distinguish between effectively Gaussian and non-Gaussian environment.
description: Presentation thoroughly improved, changed title
Rare, defective MX1 alleles increase human susceptibility to H7N9 zoonosis
Creators: name: Qijun Liao
Publisher: name: CNGB
Year: 2021
Subjects: Variation
Multiisolate
Medical

description: We report the first host genetic study in China by deeply sequencing and analyzing the 217 H7N9 patients and 116 controls. This initial study provides compelling evidence for a monogenetic etiology of severe influenza. Here, the statistical information of genetic polymorphisms and genome-wide association summary statistics data will be stored. 在这里，我们存放基因组变异统计信息和人群全基因组关联研究的统计结果，本结果不包含任何个体数据，仅保留群体分析后的统计结果。
The weight complex functor is symmetric monoidal
Creators: name: Aoki, Ko
Publisher: name: arXiv
Year: 2019
Subjects: subject: Category Theory (math.CT)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: Bondarko's (strong) weight complex functor is a triangulated functor from Voevodsky's triangulated category of motives to the homotopy category of chain complexes of classical Chow motives. Its construction is valid for any dg enhanced triangulated category equipped with a weight structure. In this paper we consider weight complex functors in the setting of stable symmetric monoidal $\infty$-categories. We prove that the weight complex functor is symmetric monoidal under a natural compatibility assumption. To prove this result, we develop additive and stable symmetric monoidal variants of the $\infty$-categorical Yoneda embedding, which may be of independent interest.
description: 8 pages
gEYEded: Subtle and Challenging Gaze-Based Player Guidance in Exploration Games
Creators: name: Lankes, Michael
name: Haslinger, Andreas
name: Wolff, Christian
Publisher: name: Universität Regensburg
Year: 2019
Subjects: subject: player guidance; gaze-based interactions; feedback types; game experience
subject: 004 Informatik

description: This paper investigates the effects of gaze-based player guidance on the perceived game experience, performance, and challenge in a first-person exploration game. In contrast to existing research, the proposed approach takes the game context into account by providing players not only with guidance but also granting them an engaging game experience with a focus on exploration. This is achieved by incorporating gaze-sensitive areas that indicate the location of relevant game objects. A comparative study was carried out to validate our concept and to examine if a game supported with a gaze guidance feature triggers a more immersive game experience in comparison to a crosshair guidance version and a solution without any guidance support. In general, our study findings reveal a more positive impact of the gaze-based guidance approach on the experience and performance in comparison to the other two conditions. However, subjects had a similar impression concerning the game challenge in all conditions.
Scaling properties of the perturbative Wilson loop in two-dimensional non-commutative Yang-Mills theory
Creators: name: Bassetto, A.
name: Nardelli, G.
name: Torrielli, A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Commutative Yang-Mills theories in 1+1 dimensions exhibit an interesting interplay between geometrical properties and U(N) gauge structures: in the exact expression of a Wilson loop with $n$ windings a non trivial scaling intertwines $n$ and $N$. In the non-commutative case the interplay becomes tighter owing to the merging of space-time and ``internal'' symmetries in a larger gauge group $U(\infty)$. We perform an explicit perturbative calculation of such a loop up to ${\cal O}(g^6)$; rather surprisingly, we find that in the contribution from the crossed graphs (the genuine non-commutative terms) the scaling we mentioned occurs for large $n$ and $N$ in the limit of maximal non-commutativity $θ=\infty$. We present arguments in favour of the persistence of such a scaling at any perturbative order and succeed in summing the related perturbative series.
description: LaTeX, 22 pages, no figures
Image ausgewählter Leguminosen – eine Umfrage bei deutschen Konsumenten und Landwirten
Creators: name: Weng, C.
name: Weng, C.
Publisher: name: Unknown
Year: 2019
Subjects: subject: Food Consumption/Nutrition/Food Safety
subject: Marketing
subject: FOS: Economics and business
subject: protein transition, consumer behavior, pulses

description: DE: Mit Blick auf den Klimawandel, die steigende Weltbevölkerung, den vermehrten Konsum von tierischen Produkten sowie die ungesunden Ernährungsweisen der Bevölkerung in Industrienationen wie Deutschland, gilt es, verträglichere Ernährungsalternativen zu etablieren. Leguminosen können Teil eines Lösungsansatzes sein. Anhand der Daten aus zwei Umfragen bei deutschen Konsumenten und Landwirten und den daraus resultierenden Variablen konnten zwei Forschungsfragen bearbeitet werden. Hauptsächlich beschäftigt sich die Studie mit dem Image von ausgewählten Leguminosen bei deutschen Konsumenten und Landwirten. Weiterhin wird durch multiple Regressionsmodelle speziell der Einfluss bestimmter Variablen auf die Absichtsänderung speziell von Konsumenten herausgestellt, Leguminosen in Verarbeitungsprodukten zu akzeptieren. Die Ergebnisse zu beiden Fragestellungen sind sehr komplex und nicht immer eindeutig interpretierbar. Jedoch liefern sie für die weitere Forschung Informationen, die eine Fokussierung auf entscheidende Einflussgrößen ermöglicht. EN: With regard to climate change, a growing world population, increased consumption of animal products and the unhealthy diets of the population in industrial nations such as Germany, it is essential to establish more compatible nutrition alternatives. Legumes can be part of a solution. Based on the data from two surveys of German consumers and farmers and the resulting variables, two research questions could be answered. The study deals mainly with the image of selected legumes among German consumers and farmers. Furthermore, the influence of certain variables on the intention of consumers to accept legumes in processed products is highlighted by multiple regression models. The results on both questions are very complex and not always clearly interpretable. However, they provide information for further research that enables a focus on decisive influencing variables.
Falklandiellus Kuschel 1950
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Falklandiellus

description: Falklandiellus Kuschel, 1950
 Falklandiellus Kuschel, 1950: 14 (type species: Falklandius suffodens Enderlein, 1907, by original designation); Morrone, 1995a: 106 (revision).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 17, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Crosslinking Collagen Constructs: Achieving Cellular Selectivity Through Modifications of Physical and Chemical Properties
Creators: name: Nair, Malavika
name: Best, Serena M.
name: Cameron, Ruth E.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: collagen
crosslinking
cellular selectivity
materials selection map

description: Collagen-based constructs have emerged in recent years as ideal candidates for tissue engineering implants. For many biomedical applications, collagen is crosslinked in order to improve the strength, stiffness and stability of the construct. However, the crosslinking process may also result in unintended changes to cell viability, adhesion or proliferation on the treated structures. This review provides a brief overview of some of both the most commonly used and novel crosslinkers used with collagen, and suggests a framework by which crosslinking methods can be compared and selected for a given tissue engineering application.
Leibniz Science Campus: Digital Transformation of Research
Creators: name: Jacyszyn, Anna M.
name: Bach, Felix
name: Razum, Matthias
name: Nierling, Linda
Publisher: name: Zenodo
Year: 2024

description: The digital transformation of research affects both academia and society as such. It comprises the adaptation of epistemological processes as well as the transparency and communication of findings. New data-driven methods not only open up innovative approaches for knowledge generation, but also raise legal, ethical and societal questions. Within the newly established Leibniz ScienceCampus “Digital Transformation of Research” (DiTraRe) we investigate the effects of the increasing digitalisation of scientific work in four research clusters, in which interdisciplinary teams of researchers, computer scientists, lawyers and sociologists work together. Based on specific challenges (use cases), the research clusters aim to develop practical solutions. In the next step, we try to apply these solutions to further use cases and thus generalise them iteratively. In the cluster “Protected data spaces”, we analyse the use of sensitive data in sports science. The cluster “Smart data acquisition” deals with Smart Lab technology such as Laboratory Information Management Systems (LIMS) and Electronic Lab Notebooks like Chemotion. The cluster “AI-based knowledge realms” focusses on artificial intelligence and machine learning in biomedical simulation and engineering. The topic of “Publication cultures” are changes in scientific publishing due to new challenges like the publication of large datasets with a use case originating in climate research.

In addition to the research clusters, the ScienceCampus includes four dimensions that consider cross-cutting topics on a meta-level, for example in the areas of legal and ethical challenges, security, tools or resonance and reflection. The last dimension in particular expands the view from science to society and how society perceives the changes in science. This concerns trust and credibility of scientific findings as well as citizen science and the assessment of the value of research for society.

In our contribution, we will present the concept of a Leibniz ScienceCampus and the specific characteristics of DiTraRe. One focus will be the interface between natural sciences and engineering on the one hand and sociology, technology assessment, law and ethics on the other. We will report on our experiences with the chosen interdisciplinary and multi-layered approach and present the first results of our work with a focus on current challenges, namely

compare current practices of publication, organisation and data management in different research disciplines,

assess current and future risks, e.g. in the field of data privacy and security,

anticipate and assess changes induced by AI, with a particular focus on the impact of generative AI and large language models (LLMs), and

design of transdisciplinary exchange on research data using innovative science communication formats towards citizens and science-society intermediaries, e.g. science journalists.
Additional file 1 of The clinical course of Duchenne muscular dystrophy in the corticosteroid treatment era: a systematic literature review
Creators: name: Szabo, Shelagh M.
name: Salhany, Renna M.
name: Deighton, Alison
name: Harwood, Meagan
name: Mah, Jean
name: Gooch, Katherine L.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Statistics
subject: FOS: Mathematics

description: Additional file 1: Supplementary Table 1. Search strategy. Supplementary Table 2. Details of corticosteroid treatment, by study. Supplementary Table 3. Details of ACE inhibitor treatment, by study. Supplementary Table 4. STROBE assessments of included studies.
Copper(II), nickel(II), zinc(II) and cadmium(II) complexes of 1,2,4-triazole based Schiff base ligand: synthesis, comparative spectroscopic, thermal, biological and molecular docking studies
Creators: name: Singh, Kiran
name: Kumari, Bavita
name: Sharma, Amit
Publisher: name: Taylor & Francis
Year: 2021
Subjects: Biophysics
Biochemistry
Physical Sciences not elsewhere classified
Cell Biology
Molecular Biology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified

description: Herein, a Schiff base ligand, 9-(((5-mercapto-4H-1,2,4-triazole-4-yl)imino)methyl)-anthracene and its metal complexes with copper(II), nickel(II), zinc(II) and cadmium(II) ions have been synthesized and systematically characterized by certain analytical and multispectral studies. Fourier transform infrared, proton nuclear magnetic resonance, microanalysis, mass spectra, electronic spectra, magnetic moment, powder X‐ray diffraction analysis, thermogravimetric-differential thermogravimetric analyses and electron spin resonance spectroscopy techniques have explicated the structure of the complexes. The copper complexes showed square planar geometry whereas other complexes are in an octahedral geometry. Metal complexes exhibited a remarkable fluorescence response. The electrochemical property, i.e., oxidation–reduction potential of copper complexes was enlightened by cyclic voltammetry. The activation thermodynamic parameters for the decomposition steps of complexes were documented using the Coats–Redfern method. Adverse antimicrobial activities of titled compounds have been studied against different microbes; in addition, 1,1-diphenyl-2-picrylhydrazyl assay was also used to evaluate the antioxidant activity of these compounds. Molecular docking was exercised to vaticinate the binding of the ligand with receptors of crystal structures of Escherichia coli, Bacillus subtilis and Candida albicans.
Optimal Optomechanical Coupling Strength in Multi-Membrane Systems
Creators: name: Newsom, David C.
name: Luna, Fernando
name: Fedoseev, Vitaly
name: Löffler, Wolfgang
name: Bouwmeester, Dirk
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We calculate the optomechanical coupling strength for a multi-membrane in a cavity system. The optimal configuration for an array of $N$ membranes placed near the center of a cavity is identified. This results in a coupling strength much greater than previously proposed multi-membrane configurations. We find that the coupling strength scales exponentially with the number of membranes until saturating due to complete localization of the field within the array. Furthermore we explore two sources of loss, those due to light absorption within the membrane(s) and leakage through the cavity's end-mirrors, and evaluate how they affect the possibility of achieving strong coupling.
description: 12 Pages, 8 Figures
Biosensors Based on Mechanical and Electrical Detection Techniques
Creators: name: Chalklen, Thomas
name: Jing, Qingshen
name: Kar-Narayan, Sohini
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: biosensors
mechanical biosensor
electrical biosensor
MEMS biosensor

description: Biosensors are powerful analytical tools for biology and biomedicine, with applications ranging from drug discovery to medical diagnostics, food safety, and agricultural and environmental monitoring. Typically, biological recognition receptors, such as enzymes, antibodies, and nucleic acids, are immobilized on a surface, and used to interact with one or more specific analytes to produce a physical or chemical change, which can be captured and converted to an optical or electrical signal by a transducer. However, many existing biosensing methods rely on chemical, electrochemical and optical methods of identification and detection of specific targets, and are often: complex, expensive, time consuming, suffer from a lack of portability, or may require centralised testing by qualified personnel. Given the general dependence of most optical and electrochemical techniques on labelling molecules, this review will instead focus on mechanical and electrical detection techniques that can provide information on a broad range of species without the requirement of labelling. These techniques are often able to provide data in real time, with good temporal sensitivity. This review will cover the advances in the development of mechanical and electrical biosensors, highlighting the challenges and opportunities therein.
Investigating the Relationship Between Emotion Recognition Software and Usability Metrics
Creators: name: Schmidt, Thomas
name: Schlindwein, Miriam
name: Lichtner, Katharina
name: Wolff, Christian
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: Affective computing; usability engineering; usability; sentiment analysis; emotion analysis; usability test; system usability scale
subject: 004 Informatik
subject: 150 Psychologie

description: Due to progress in affective computing, various forms of general purpose sentiment/emotion recognition software have become available. However, the application of such tools in usability engineering (UE) for measuring the emotional state of participants is rarely employed. We investigate if the application of sentiment/emotion recognition software is beneficial for gathering objective and intuitive data that can predict usability similar to traditional usability metrics. We present the results of a UE project examining this question for the three modalities text, speech and face. We perform a large scale usability test (N = 125) with a counterbalanced within-subject design with two websites of varying usability. We have identified a weak but significant correlation between text-based sentiment analysis on the text acquired via thinking aloud and SUS scores as well as a weak positive correlation between the proportion of neutrality in users’ voice and SUS scores. However, for the majority of the output of emotion recognition software, we could not find any significant results. Emotion metrics could not be used to successfully differentiate between two websites of varying usability. Regression models, either unimodal or multimodal could not predict usability metrics. We discuss reasons for these results and how to continue research with more sophisticated methods.
Ubiquitin-Like Modifiers: Emerging Regulators of Protozoan Parasites
Creators: name: Karpiyevich, Maryia
name: Artavanis-Tsakonas, Katerina
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: ubiquitin-like
SUMO
NEDD8
ATG8
ATG12
URM1
UFM1
parasite
protozoa
post- translational regulation

description: Post-translational protein regulation allows for fine-tuning of cellular functions and involves a wide range of modifications, including ubiquitin and ubiquitin-like modifiers (Ubls). The dynamic balance of Ubl conjugation and removal shapes the fates of target substrates, in turn modulating various cellular processes. The mechanistic aspects of Ubl pathways and their biological roles have been largely established in yeast, plants, and mammalian cells. However, these modifiers may be utilised differently in highly specialised and divergent organisms, such as parasitic protozoa. In this review, we explore how these parasites employ Ubls, in particular SUMO, NEDD8, ATG8, ATG12, URM1, and UFM1, to regulate their unconventional cellular physiology. We discuss emerging data that provide evidence of Ubl-mediated regulation of unique parasite-specific processes, as well as the distinctive features of Ubl pathways in parasitic protozoa. We also highlight the potential to leverage these essential regulators and their cognate enzymatic machinery for development of therapeutics to protect against the diseases caused by protozoan parasites.
Falklandiellus suffodens
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Falklandiellus
Falklandiellus suffodens

description: Falklandiellus suffodens (Enderlein, 1907)
 Falklandius suffodens Enderlein, 1907: 68 (type locality: Argentina: Falkland Islands (Islas Malvinas), near Hookers Point; type material: S: NHRS).
 Falklandius inaequalis Champion, 1918a: 184 (type locality: Argentina: Falkland Islands (Islas Malvinas), Port Stanley; type material: S: 1 BMNH); Kuschel, 1952: 137 (= Falklandiellus suffodens).
 Falklandiellus suffodens; Kuschel, 1950: 14.
 Host plants. Bryophytes (Morrone, 1995a).
 Distribution. Southern Argentina, including the Falkland Islands (Islas Malvinas), and southern Chile (Morrone, 1995a; Posadas, 2008).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 17, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Massive Warm/Hot Galaxy Coronae: II. Isentropic Model
Creators: name: Faerman, Yakov
name: Sternberg, Amiel
name: McKee, Christopher F.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We construct a new analytic phenomenological model for the extended circumgalactic material (CGM) of $L^*$ galaxies. Our model reproduces the OVII/OVIII absorption observations of the Milky Way (MW) and the OVI measurements reported by the COS-Halos and eCGM surveys. The warm/hot gas is in hydrostatic equilibrium in a MW gravitational potential, and we adopt a barotropic equation of state, resulting in a temperature variation as a function of radius. A pressure component with an adiabatic index of $γ=4/3$ is included to approximate the effects of a magnetic field and cosmic rays. We introduce a metallicity gradient motivated by the enrichment of the inner CGM by the Galaxy. We then present our fiducial model for the corona, tuned to reproduce the observed OVI-OVIII column densities, and with a total mass of $M_{\rm gas} \approx 5.5 \times 10^{10}~{\rm M_{\odot}}$ inside $r_{\rm cgm} \approx 280$ kpc. The gas densities in the CGM are low ($n_{\rm H} = 10^{-5} - 3 \times 10^{-4}~{\rm cm^{-3}}$) and its collisional ionization state is modified by the metagalactic radiation field (MGRF). We show that for OVI-bearing warm/hot gas with typical observed column densities $N_{\rm OVI} \sim 3 \times 10^{14}~{\rm cm^{-2}}$ at large ($\gtrsim 100$ kpc) impact parameters from the central galaxies, the ratio of the cooling to dynamical times, $t_{\rm cool}/t_{\rm dyn}$, has a model-independent upper limit of $\lesssim 4$. In our model, $t_{\rm cool}/t_{\rm dyn}$ at large radii is $\sim 2-3$. We present predictions for a wide range of future observations of the warm/hot CGM, from UV/X-ray absorption and emission spectroscopy, to dispersion measure (DM) and Sunyaev-Zeldovich CMB measurements. We provide the model outputs in machine-readable data files, for easy comparison and analysis.
description: 24 pages, 15 figures. Accepted to ApJ
Towards the Analysis of Fan Fictions in German Language: Exploration of a Corpus from the Platform Archive of Our Own
Creators: name: Schmidt, Thomas
name: Grünler, Johanna
name: Schönwerth, Nicole
name: Wolff, Christian
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: fan fiction, online writing, digital humanities, literary studies, fan studies, online communities, corpus creation, corpus analysis
subject: 004 Informatik
subject: 400 Sprachwissenschaft, Linguistik
subject: 420 Englisch
subject: 800 Literatur, Rhetorik, Literaturwissenschaft
subject: 830 Deutsche Literatur

description: We report upon a digital humanities project on the acquisition and analysis of a corpus of German online writings. We have implemented a scraper to gather the German language material as well as corresponding metadata of the popular online writing platform Archive of Our Own (AO3), which is a platform primarily focused on the text sort of fan fictions. The corpus consists of 9,640 writings resulting in over 39 million tokens and 3.6 million sentences. The texts have varying lengths with a median of around 2,500 tokens per story. We present results on the analysis of metadata and general text statistics like the most frequent words. While we can support previous findings of literary and media studies like the dominance of male-male romantic and erotic narratives, we can also identify attributes that are very specific and unique to German culture as well as differences to results of research for English online writings. We will outline in our future work how we plan to further increase and analyze the corpus to support research in digital humanities as well as German literary and fan studies. (PDF) Towards the Analysis of Fan Fictions in German Language: Exploration of a Corpus from the Platform Archive of Our Own.
A game-theoretic optimisation approach to fair customer allocation in oligopolies
Creators: name: Charitopoulos, Vassilis M.
name: Dua, Vivek
name: Pinto, Jose M.
name: Papageorgiou, Lazaros G.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Research Article
Game theory
Supply chain optimisation
Oligopoly
Nash equilibrium
Customer allocation

description: Abstract: Under the ever-increasing capital intensive environment that contemporary process industries face, oligopolies begin to form in mature markets where a small number of companies regulate and serve the customer base. Strategic and operational decisions are highly dependent on the firms’ customer portfolio and conventional modelling approaches neglect the rational behaviour of the decision makers, with regards to the problem of customer allocation, by assuming either static competition or a leader-follower structure. In this article, we address the fair customer allocation within oligopolies by employing the Nash bargaining approach. The overall problem is formulated as mixed integer program with linear constraints and a nonlinear objective function which is further linearised following a separable programming approach. Case studies from the industrial liquid market highlight the importance and benefits of the proposed game theoretic approach.