cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Integrating site-specific dispersion modeling into life cycle assessment, with a focus on inhalation risks in chemical production
Creators: name: Tian, Shen
name: Bilec, Melissa
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Hematology

description: It has become increasingly important for environmental managers to evaluate the human health (HH) impact of chemicals in their supply chain. Current life cycle assessment (LCA) methods are limited because they often only address the HH impact at large geographical scales. This paper aims to develop a method that derives a regionalized life cycle inventory data set and site-specific air dispersion modeling to evaluate the HH impact of chemicals along the life cycle phases at finer geographical scales to improve decision-making, with focus on inhalation pathway. More specifically, cancer risk and noncancer hazard index (HI) are quantified at the county level to identify high-risk regions and at the census tract level to reveal the geographical pattern of health impacts. The results showed that along the cradle-to-gate life cycle stages of a widely used chemical, methylene diphenyl diisocyanate (MDI), the accumulative inhalation risk was 3 orders of magnitude below the U.S. Environmental Protection Agency (EPA) risk management thresholds for both cancer risk (2.16 × 10−9) and noncancer HI (1.53 × 10−3). However, the absolute value of inhalation risks caused by the case study chemicals varied significantly in different geographical areas, up to 4 orders of magnitude. This paper demonstrates a feasible approach to improve human health impact assessment (HHIA) by combining site-specific air dispersion modeling and LCA using publicly available inventory data. This proposed method complements existing life cycle impact assessment (LCIA) models to improve HHIA by employing both HH risk assessment and LCA techniques. One potential outcome is to prioritize pollution prevention and risk reduction measures based on the risk maps derived from this method. Implications: It has become increasingly important for environmental managers to evaluate the human health impacts of chemicals in their supply chain. Regionalized life cycle inventory data sets should be developed using publically available databases such as EPA’s toxic release inventory. The combination of site-specific dispersion modeling and life cycle assessment modeling can improve human health impact assessment of chemicals by providing more regionalized results along their supply chain.
Localization of Gravitino on a Brane
Creators: name: Oda, Ichiro
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We show how the spin 3/2 gravitino field can be localized on a brane in a general framework of supergravity theory. Provided that a scalar field coupled to the Rarita-Schwinger field develops an vacuum expectation value (VEV) whose phase depends on the 'radial' coordinate in extra internal space, the gravitino is localized on a brane with the exponentially decreasing warp factor by selecting an appropriate value of the VEV.
description: 7 pages, LaTex 2e, no figures
Acarus exulcerans Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Acaridae
Acarus
Acarus exulcerans

description: Acarus exulcerans [spec. nov.]
A. pedibus longissimis setaceis: anticis duobus brevibus.
Habitat in Scabie ferina.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 617, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Biodiversity offsets for moving conservation targets
Creators: name: Bull, Joseph
Publisher: name: Imperial College London
Year: 2014

description: Conservation is difficult for moving targets, such as migratory species or landscapes subject to environmental change. Biodiversity offsetting is a novel approach that involves active compensation for biodiversity lost through development, with an objective of no net loss of biodiversity overall. In this thesis, I explore the use of biodiversity offsets for moving targets. My case study is the conservation of the migratory saiga antelope Saiga tatarica alongside industry in the Ustyurt plateau, Uzbekistan. Key challenges for offsetting include: specification of an appropriate frame of reference for evaluating no net loss, determination of requisite ecological gains, and the degree of flexibility permitted in biodiversity trades. I use bespoke simulation models to predict whether no net loss of biodiversity can be achieved within various hypothetical frames of reference, i.e. against different socio-ecological baselines and counterfactual scenarios. The reference frame determines the feasibility and effort required in achieving conservation objectives, and I shed light upon those ecosystem dynamics for which offsets may be appropriate. I develop a socio-ecological counterfactual for saigas and their Ustyurt habitat, relying upon satellite imagery and secondary data sets. Even with limited data, it proves possible to develop an instructive counterfactual for intervention. To calculate offset requirements, I first quantify impacts of industrial activity on the Ustyurt. Vegetation impacts are measured, mapped and projected to the landscape scale, and the influence on mobile species such as saigas is considered. Via quantitative comparison, I show that the application of different available offset calculation methodologies to these data – which all purport to achieve no net loss of biodiversity – would result in divergent offset requirements. This implies that offset methodologies should be tailored to specific moving target problems, rather than generalised. Finally, I use conservation planning software to compare the performance of flexible and non-flexible offsets. Zonation is used to model the effect of permitting flexibility in the biological, spatial and temporal constraints placed upon offsetting, and RobOff to assess the optimum return on investment under uncertainty. I find that a mixture of flexible and non-flexible offsets is desirable for conserving moving targets in the Ustyurt. We must give deeper consideration to the dynamic nature of ecosystems when designing conservation interventions. Biodiversity offsets have potential in this regard. To realise the potential, we should specify appropriate frames of reference, tailor metrics, and consider allowing flexible biodiversity trades.
Oral history interview with Sally Michael Avery, 1979
Publisher: name: Columbia University
Year: 2021
Subjects: Women artists
Artists
Art, Modern--20th century
Art criticism
Painting
Art galleries, Commercial

description: Childhood, family and education; marriage to Milton Avery; daughter, March; career as painter; reminiscences of Milton Avery: family background, influence of childhood and nature on painting, work for Works Progress Administration, prizes, painting philosophy, techniques and uses of media, work habits, relationship with art critics, associations with galleries; Avery family members' exhibitions and retrospectives, 1928-78; recollections of Mark Rothko, Adolph Gottlieb, Marsden Hartley, Marcel Duchamp, Joseph Hirshhorn and others
Acarus geniculatus Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Acaridae
Acarus
Acarus geniculatus

description: Acarus geniculatus [spec. nov.]
A. niger, femorum geniculis subglobosis. Faun. svec. 1210.
Habitat ..
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 617, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
On the Cluster Sunyaev-Zel'dovich Effect and Hubble Constant
Creators: name: Cen, Renyue
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: This study shows one important effect of preexistent cosmic microwave background temperature fluctuations on the determination of the Hubble constant through Sunyaev-Zel'dovich effect of clusters of galaxies, especially when coupled with the gravitational lensing effect by the same clusters. The effect results in a broad distribution of the apparent Hubble constant. The combination of this effect with other systematic effects such as the Loeb-Refregier Effect seems to provide an explanation for the observationally derived values of the Hubble constant currently available based on the Sunyaev-Zel'dovich effect, if the true value of the Hubble constant is 60-80 km/s/Mpc. It thus becomes possible that the values of the Hubble constant measured by other techniques which generally give a value around 60-80 km/s/Mpc be reconciled with the SZ effect determined values of the Hubble constant, where are systematically lower than others and have a broad distribution.
description: ApJ Lett in press
title: ADCO, Ordre cistercien : comptes (1499-1515) (11 H 1162), f. 00184
Creators: name: de la Côte-d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Ordre cistercien : comptes (1499-1515), Archives départementales de la Côte-d'Or, (11 H 1162). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1499-1515), Archives départementales de la Côte-d'Or, (11 H 1162), f. 00184, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
One-loop renormalization of the QCD Schrödinger functional
Creators: name: Sint, Stefan
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: In a previous publication, we have constructed the Schrödinger functional in Wilson's lattice QCD. It was found that the naive continuum limit leads to a well-defined classical continuum theory. Starting from the latter, a formal continuum definition of the Schrödinger functional is given and its saddle point expansion is carried out to one-loop order of perturbation theory. Dimensional regularization and heat kernel techniques are used to determine the one-loop divergences. These are partly canceled by the usual renormalizations of the quark mass and the coupling constant in QCD. An additional divergence can be absorbed in a multiplicative renormalization of the quark boundary fields. The corresponding boundary counterterm is a local polynomial in the fields, so that we confirm a general expectation of Symanzik.
description: 31 pages, uuencoded postscript file, no figures
Quantum Entanglement in Multi-field Inflation
Creators: name: Bolis, Nadia
name: Fujita, Tomohiro
name: Mizuno, Shuntaro
name: Mukohyama, Shinji
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the emergence of quantum entanglement in multi-field inflation. In this scenario, the perturbations of one field contribute to the observable curvature perturbation, while multi-field dynamics with the other fields affect the curvature perturbation through particle production and entanglement. We develop a general formalism which defines the quantum entanglement between the perturbations of the multiple fields both in the Heisenberg and Schrödinger pictures, and show that entanglement between different fields can arise dynamically in the context of multi-field inflationary scenarios. We also present a simple model in which a sudden change in the kinetic matrix of the scalar fields generates entanglement and an oscillatory feature appears in the power spectrum of the inflaton perturbation.
description: 25 pages, 1 figure, references added
Disk formation in the collapse of supramassive neutron stars
Creators: name: Camelio, Giovanni
name: Dietrich, Tim
name: Rosswog, Stephan
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Short gamma-ray bursts (sGRBs) show a large diversity in their properties. This suggests that the observed phenomenon can be caused by different "central engines" or that the engine produces a variety of outcomes depending on its parameters, or possibly both. The most popular engine scenario, the merger of two neutron stars, has received support from the recent Fermi and INTEGRAL detection of a burst of gamma rays (GRB170817A) following the neutron star merger GW170817, but at the moment it is not clear how peculiar this event potentially was. Several sGRBs engine models involve the collapse of a supramassive neutron star that produces a black hole plus an accretion disk. We study this scenario for a variety of equations of states both via angular momentum considerations based on equilibrium models and via fully dynamical Numerical Relativity simulations. We obtain a broader range of disk forming configurations than earlier studies but we agree with the latter that none of these configurations is likely to produce a phenomenon that would be classified as an sGRB.
description: accepted by MNRAS
The extremal limit of D-dimensional black holes
Creators: name: Caldarelli, M.
name: Vanzo, L.
name: Zerbini, S.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The extreme limit of a class of D-dimensional black holes is revisited. In the static limit, it is shown that well defined extremal limiting procedure exists and it leads to new solutions of the type AdS2 times constant curvature symmetric spaces.
description: 8 pages, proceedings of Londrina Conference, April 2000, Londrina, Brazil
Condensed matter applications of the Gauge/Gravity correspondence
Creators: name: Pantelidou, Christiana
Publisher: name: Imperial College London
Year: 2014

description: In this thesis, we investigate non-perturbative features of strongly coupled condensed matter systems, generically, placed at finite temperature, charge density and, possibly, in a magnetic field using the theoretical framework of the gauge/gravity correspondence. According to the dictionary of the duality, such field theories are related to charged black holes in one dimension higher that emerge from weakly interacting gravity theories. Following this approach, progress has been made in understanding some of the universal features of field theories at strong coupling, with new classes of black holes being discovered along the way. The bulk of the thesis consists of four interconnected parts. In the first, we study magnetically charged black holes and we find that, at some critical temperature, a new branch of spatially modulated branes appears, corresponding to a dual field theory with a current density wave. In the second part, we investigate the ground state of strongly coupled field theories placed in magnetic field, within the context of gauged supergravity in D=4,5 dimensions. This analysis revealed a rich structure of instabilities and, in particular, showed that only the supersymmetric solutions correspond to stable configurations. In the third part, we consider a generalised version of local quantum critical points, called η-geometries, in the context of U(1)^4 supergravity in D=4 dimensions. We show that the latter theory admits extremal black holes carrying three non-zero electric or magnetic charges which approach an η=1 geometry in the IR, while a small fourth charge resolves the singularity of the η-geometry replacing it with an AdS_2XR^2 factor in the far IR. Finally, in the last part, we discuss the possibility of spatially modulated superconductors. We construct electrically charged black holes dual to four dimensional CFTs in a superfluid phase with either p-wave or (p+ip)-wave order and we discuss their thermodynamic properties, the corresponding ground states as well as the competition of the two types of order.
Additional file 7: of A novel R2R3-MYB from grape hyacinth, MaMybA, which is different from MaAN2, confers intense and magenta anthocyanin pigmentation in tobacco
Creators: name: Chen, Kaili
name: Du, Lingjuan
name: Liu, Hongli
name: Liu, Yali
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Figure S7. Scanning electron microscopy images of leaf and corolla adaxial surface cells in different tobacco genotypes. The leaf (a-c) and corolla (d-f) adaxial surface cells are shown for the control (a, d), OE-MaAN2 (b, e), and OE-MaMybA (c, f) tobacco. (DOCX 145 kb)
Pedestrian detection and identification
Creators: name: Fei, Ran
Publisher: name: Imperial College London
Year: 2014

description: People are the centre of technologies. Understanding, monitoring and tracking the behaviour of people will benefit in various areas including driving assistance, surveillance for safety and caring purposes and applications for machine-people interaction. Particularly, pedestrians attract more attention for two reasons: they restrict the behaviours of people to standing and moving upright; and applications for pedestrian detection and monitoring have positively impact on the quality of life. Pedestrian detection and identification, aims at recognising pedestrians fromstill images and video frames. Together with pedestrian recognition and tracking, this topic attempts to train computers to recognise a pedestrian. The problem is challenging. Though frameworks were designed, various algorithms were proposed in recent years, further efforts are needed to improve the accuracy and reliability of the performance. In this thesis, proposing a modifiable framework for pedestrian identification and improving the performances of current pedestrian detection techniques are particularly focused. Based on appearance based pedestrian identification, a modifiable framework is a novel philosophy of developing frameworks which can be easily improved. For pedestrian identification, a novel protocol where layers of algorithms are hierarchically applied to solve the problem. To compare the detected pedestrians, appearance based features are selected, the "bag-of-features" framework is employed to compare the histogram descriptions of pedestrians. To improve the performances of HOG pedestrian detector, the presence of head-shoulder structure is selected as the evidence of the presence of pedestrian. A novel appearance based framework is developed to detect the head-shoulder structure from the detection results of HOG detector. Furthermore, in order to separate multiple pedestrians detected in one bounding box, a novel algorithm is proposed to detect the approximated symmetry axes of pedestrians.
High Velocity Clouds: Building Blocks of the Local Group
Creators: name: Blitz, Leo
name: Spergel, David N.
name: Teuben, Peter J.
name: Hartmann, Dap
name: Burton, W. Butler
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We suggest that the high--velocity clouds (HVCs) are large clouds, with typical diameters of 25 kpc and containing 5e7 solar masses of neutral gas and 3e8 solar masses of dark matter, falling onto the Local Group; altogether the HVCs contain 10$^{11}$ solar masses of neutral gas. Our reexamination of the Local-Group hypothesis for the HVCs connects their properties to the hierarchical structure formation scenario and to the gas seen in absorbtion towards quasars. We begin by showing that at least one HVC complex (besides the Magellanic Stream) must be extragalactic at a distance > 40 kpc from the Galactic center, with a diameter > 20 kpc and a mass > 1e8 solar masses. We interpret the more distant HVCs as dark matter ``mini--halos'' moving along filaments towards the Local Group. Most poor galaxy groups should contain HI structures to large distances bound to the group. The HVCs are local analogues of the Lyman--limit clouds We argue that there is a Galactic fountain in the Milky Way, but that the fountain does not explain the origin of the HVCs. Our analysis of the HI data leads to the detection of a vertical infall of low-velocity gas towards the plane. This implies that the chemical evolution of the Galactic disk is governed by episodic infall of metal-poor HVC gas that only slowly mixes with the rest of the interstellar medium. The Local--Group infall hypothesis makes a number of testable predictions. The HVCs should have sub-solar metallicities. Their H$α$ emission should be less than that seen from the Magellanic Stream. The clouds should not be seen in absorption to nearby stars. The clouds should be detectable in both emission and absorption around other groups.
description: 65 pages, 27 figures (26 postscript, 1 gif). Submitted to Astrophysical Journal Full figures and paper available at http://www.astro.princeton.edu/~dns/
On operator relations for gravitational form factors of a spin-0 hadron
Creators: name: Tanaka, Kazuhiro
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The gravitational form factors for a hadron, the form factors for the hadron matrix element of the QCD energy-momentum tensor, not only describe the coupling of the hadron with a graviton, but also serve as unique quantities for describing the shape inside the hadron reflecting dynamics of quarks and gluons, such as the internal shear forces acting on the quarks/gluons and their pressure distributions. We consider the quark contribution to the gravitational form factors for a (pseudo)scalar hadron, and derive and clarify the relations satisfied by them as direct consequences of the symmetries and the equations of motion in QCD, and connections to the generalized parton distributions. Our results reveal the connections between the gravitational form factors and the higher-twist quark-gluon correlation effects inside the hadrons.
description: 20 pages, typos corrected, version published in Phys. Rev. D
Background field technique and renormalization in lattice gauge theory
Creators: name: Luescher, Martin
name: Weisz, Peter
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Lattice gauge theory with a background gauge field is shown to be renormalizable to all orders of perturbation theory. No additional counterterms are required besides those already needed in the absence of the background field. The argument closely follows the treatment given earlier for the case of dimensional regularization by Kluberg-Stern and Zuber. It is based on the BRS, background gauge and shift symmetries of the lattice functional integral.
description: 26 pages, uuencoded compressed postscript file
Oral history interview with Sally Nafe 1997
Publisher: name: Columbia University
Year: 2019

description: Childhood: Philadelphia, Quaker religion, B.A. English Swarthmore College; children’s publishing; marriage to John Elliott Nafe [Jack Nafe], 1941; chairman Palisades Library; reminiscences of Jack Nafe: born 1914 Seattle, Washington; seaman, 1932-1934; B.S. physics University of Michigan; M.S. physics Washington University of St. Louis; physics instructor United States Naval Academy, Annapolis, Maryland, 1941-1945; Ph..D physics Columbia University [CU], 1945-1948; research director Hudson Laboratory; Lamont-Doherty Earth Observatory [LDEO], 1954-1980: geophysics’ emergence; social life; grounds; visiting professors; trip Bogota, Columbia; research vessel expeditions; sabbaticals Cambridge University; CU Chairman of the Graduate Faculties in Science, CU Geophysics Department Chair; LDEO directorship changes; CU Vietnam War protests; LDEO and CU funding conflicts; LDEO staff reminiscences.
Development of a non-viral gene therapy strategy for choroideremia
Creators: name: Ostad-Saffari, Elham
Publisher: name: Imperial College London
Year: 2011

description: Non-viral plasmids harbouring scaffold matrix attachment regions (S/MARs) provide stable and functional episomal maintenance, resistance to epigenetic silencing and have been shown to be capable of sustained expression in murine tissues. S/MARs are an attractive alternative to conventional viral gene delivery vectors due to their low toxicity and reduced immunogenicity. This thesis documents the development of this novel non-viral episomal plasmid DNA (pDNA) expression system for persistently expressing vectors for Choroideremia (CHM) gene therapy. To this end, our goal was to analyse the ability of S/MAR plasmids to generate efficient and stable transgene expression in the mouse retina following subretinal injections. We generated and analysed a series of S/MAR constructs expressing either REP1 cDNA or the reporter enhanced green fluorescent protein (EGFP) or Luciferase (Luc) genes driven by the elongation factor-1 short (EFS) or cytomegalovirus (CMV) early enhancer/chicken beta actin (CAG) promoter. We demonstrate using the AtT20 cell line, the principle that S/MAR containing plasmids can provide long-term episomal EGFP and REP1 transgene expression in vitro. Furthermore, long-term REP1 expression was also analysed in CHM fibroblasts, where we showed in preliminary experiments that DNA constructs expressing REP1 were able to rescue CHM derived cells by rescue of their Rab27a prenylation defect and provide long-term expression of hREP1 after transfection of human and mouse CHM fibroblasts. We also developed an optimised method for delivering S/MAR containing plasmids in the eye via subretinal injections of complexed pDNAs, and provide evidence for the utility and versatility of S/MAR plasmids in ocular tissue. We show for the first time the longitudinal transgene expression of Luc in the retina as measured using bioluminescent imaging. Long- term maintenance and expression of EGFP and REP1 transgenes were also observed by PCR and Western blot analysis. Further analysis provided evidence for the long term episomal maintenance of these vectors in the eye as shown by Southern analysis. We provide evidence for the superiority of an S/MAR containing plasmid in providing long-term expression in the eye. All control pDNA constructs were shown to be incapable of sustaining significant transgene expression beyond one-month following pDNA delivery. We further demonstrate the lack of toxicity within the eye and show that fundus examinations as well as detailed histological examinations of retinal sections do not elicit an inflammatory response to our plasmids once subretinally injected in the eye. Finally, we explored the therapeutic potential of the REP1-S/MAR episome, by subretinally injecting mouse models of CHM. Further repeat experiments in CHM mouse models would add confidence to the overall experiments; however initial findings were encouraging where a partial correction of the REP1 protein and functional rescue in the eye was shown.
Oral history interview with Salvador, 1980
Publisher: name: Columbia University
Year: 2020
Subjects: Drug addicts--United States
Drug dealers--United States
Imprisonment--United States
Drug traffic--History--20th century.--United States
Drug abuse--History--20th century.--United States
Heroin abuse--History--20th century.--United States
Opium abuse--History--20th century.--United States
Methadone maintenance--History--20th century.--United States

description: In this interview, Salvador discusses his life in New York City, with respect to his drug use and trafficking. He describes using opium and heroin. He discusses in depth his heroin trafficking including his suppliers, his clientele, his prices, and the location he sold from. He compares the quality and price of heroin across decades in the twentieth century. He reviews his arrest history, and estimates having spent a total of fourteen years incarcerated in his lifetime. He describes how he was able to smuggle heroin into federal prison in Atlanta, Georgia. He describes joining a methadone program in the early 1970s, and gives his opinion of the program. He reviews his health issues including emphysema, ulcers, and back pain
Acarus aquaticus Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Acaridae
Acarus
Acarus aquaticus

description: Acarus aquaticus [spec. nov.]
A. abdomine depresso tomentoso postice obtuso, aquaticus. Fn. svec. 1199.
Frisch. ins. 8 t. 3.
Roes. suppl. 1. t. 25.
Habitat in Europae aquis dulcibus.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 617, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Robust and Scalable Models of Microbiome Dynamics
Creators: name: Gibson, Travis E.
name: Gerber, Georg K.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Microbes are everywhere, including in and on our bodies, and have been shown to play key roles in a variety of prevalent human diseases. Consequently, there has been intense interest in the design of bacteriotherapies or "bugs as drugs," which are communities of bacteria administered to patients for specific therapeutic applications. Central to the design of such therapeutics is an understanding of the causal microbial interaction network and the population dynamics of the organisms. In this work we present a Bayesian nonparametric model and associated efficient inference algorithm that addresses the key conceptual and practical challenges of learning microbial dynamics from time series microbe abundance data. These challenges include high-dimensional (300+ strains of bacteria in the gut) but temporally sparse and non-uniformly sampled data; high measurement noise; and, nonlinear and physically non-negative dynamics. Our contributions include a new type of dynamical systems model for microbial dynamics based on what we term interaction modules, or learned clusters of latent variables with redundant interaction structure (reducing the expected number of interaction coefficients from $O(n^2)$ to $O((\log n)^2)$); a fully Bayesian formulation of the stochastic dynamical systems model that propagates measurement and latent state uncertainty throughout the model; and introduction of a temporally varying auxiliary variable technique to enable efficient inference by relaxing the hard non-negativity constraint on states. We apply our method to simulated and real data, and demonstrate the utility of our technique for system identification from limited data and gaining new biological insights into bacteriotherapy design.
description: ICML 2018
On the dimensional reduced theories
Creators: name: Cognola, G.
name: Zerbini, S.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The procedure of the dimensional reduction related to the partition function of a quantum field living in curved space-time which is the warp product of a symmetric space is investigated.
description: 9 pages, proceeding of Londrina Conference, April 2000, Londrina, Brazil
Scanning DMA Data Analysis II. Integrated DMA-CPC Instrument Response and Data Inversion
Creators: name: Huajun Mai
name: Weimeng Kong
name: Seinfeld, John H.
name: Flagan, Richard C.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Analysis of scanning electrical mobility spectrometer (SEMS) or SMPS data requires coupling the scanning differential mobility analyzer (DMA) transfer function with the response functions for the instrument plumbing and the detector. In the limit of plug flow (uniform velocity) within the DMA, the scanning DMA transfer function has the same form as that for constant voltage. Most SEMS/SMPS data analysis uses this model though previous studies have shown that boundary layers distort the transfer function during scanning DMA measurements. Part I determined the instantaneous transfer function during scanning of the TSI Model 3081A long column DMA by modeling the flows, fields, and particle trajectories within the actual DMA geometry. This study (Part II) combines that transfer function with empirical data on the efficiencies and delay time distributions of the plumbing and detector of the SEMS/SMPS to determine the instantaneous rate at which particles are counted, and integrates the count rate over the finite counting time interval to obtain the integrated SEMS/SMPS response function. Simulations using this geometrical model are compared with those obtained using traditional, idealized DMA models for scan rates ranging from slow (240 s) to very fast (10 s), and with measurements of monodisperse calibration aerosols. Data inversion studies show that both increasing and decreasing voltage scans can be used to determine the particle size distribution, even with fast scans.
Additional file 1 of Can health service equity alleviate the health expenditure poverty of Chinese patients? Evidence from the CFPS and China health statistics yearbook
Creators: name: Tang, Shaoliang
name: Yao, Ling
name: Ye, Chaoyu
name: Li, Zhengjun
name: Yuan, Jing
name: Tang, Kean
name: Qian, David
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Additional file 1.
Semiconductor technology for detection of DNA methylation based biomarkers in early screening of cancer
Creators: name: Kalofonou, Melpomeni
Publisher: name: Imperial College London
Year: 2013

description: The role of DNA methylation based biomarkers in several stages of cancer development is a rapidly advancing area of research. The aberrancies on the methylation profile of gene promoters play a critical role in gene silencing, thus contributing in different phases of tumour initiation, progression and recurrence, also associated with predicting the response to chemotherapeutic agents, therefore leading to a better assessment of the clinical effectiveness of cancer therapies and so of better prognosis. The need for detection of DNA methylation has become one of the most important assays in early cancer screening. This work introduces the use of semiconductor technology for detection of DNA methylation based biomarkers in CMOS for early screening of cancer using the Ion-Sensitive Field-Effect Transistor (ISFET). This enables label-free detection of DNA methylation in gene markers of interest associated with tumour development in different organs, ultimately enabling a Point-of-Care (PoC) system for early cancer diagnosis. Towards this goal, we introduce the concept of ratiometric detection using the ``Methylation Cell" which allows continuous computation of the DNA methylation ratio. This was demonstrated through a Lab-on-Chip (LoC) system using low power current-mode translinear circuits fabricated in unmodified CMOS. Complementary to this, a novel implementation of the ``Gilbert Gain Cell" integrated with ISFET sensors was proposed, referred to as the ISFET based Chemical Gilbert Cell, a current-mode circuit for differential reaction monitoring of pH signals derived from DNA methylation reactions. The Cell achieves elimination of common non-idealities of ISFETs such as drift reduction and temperature variations, while achieving gain tunability.
title: ADCO, Cinquième cartulaire de Saint-Étienne de Dijon (1664), Cart. 28 (G 132), 258 folios, f. 00275
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cinquième cartulaire de Saint-Étienne de Dijon (1664), Archives départementales de la Côte-d'Or, Cart. 28 (G 132), 258 folios, f. 00275, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cinquième cartulaire de Saint-Étienne de Dijon (1664), Archives départementales de la Côte-d'Or, Cart. 28 (G 132), 258 folios, f. 00275, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Whole aero-engine meshing and CFD simulation
Creators: name: Wang, Feng
Publisher: name: Imperial College London
Year: 2013

description: Aero-engine components are strongly coupled with each other and traditional design tools are not always able to predict the complex phenomenon caused by component interactions. Whole engine simulations could allow designers to capture this phenomenon, increase the design confidence and reduce design cycles. The aim of this thesis is to reduce the turnover time in the pre-processing of whole engine simulations and conduct CFD simulations of the whole engine gas path. This thesis has developed a set of meshing methods for turbomachinery applications. These methods include multi-block structured meshing, 2D/3D Delaunay triangulation, Q-morph, hybrid meshing and hex meshing. These meshing methods are integrated with the in-house geometry database to reduce the required man-hours in the pre-processing of whole engine simulations. This has reduced the required man-hours from days and weeks to a few hours. The whole engine simulation benefits from the development of the developed preprocessing tool, so that the whole engine gas path can be simulated. A compressible reacting gas model is used throughout the domain to ensure the consistency of gas thermodynamic properties. The turnover time of the preprocessing of a whole engine simulation can be reduced to roughly 8 man hours (one working day), which makes the whole engine simulation a feasible tool in the design process.
Dual Polynomials of the Multi-Indexed ($q$-)Racah Orthogonal Polynomials
Creators: name: Odake, Satoru
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Classical Analysis and ODEs (math.CA)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We consider dual polynomials of the multi-indexed ($q$-)Racah orthogonal polynomials. The $M$-indexed ($q$-)Racah polynomials satisfy the second order difference equations and various $1+2L$ ($L\geq M+1$) term recurrence relations with constant coefficients. Therefore their dual polynomials satisfy the three term recurrence relations and various $2L$-th order difference equations. This means that the dual multi-indexed ($q$-)Racah polynomials are ordinary orthogonal polynomials and the Krall-type. We obtain new exactly solvable discrete quantum mechanics with real shifts, whose eigenvectors are described by the dual multi-indexed ($q$-)Racah polynomials. These quantum systems satisfy the closure relations, from which the creation/annihilation operators are obtained, but they are not shape invariant.
description: 31 pages. arXiv admin note: text overlap with arXiv:1804.10352. Comments added, typo corrected. To appear in PTEP
RVSAO 2.0: Digital Redshifts and Radial Velocities
Creators: name: Kurtz, Michael J.
name: Mink, Douglas J.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: RVSAO is a set of programs to obtain redshifts and radial velocities from digital spectra. RVSAO operates in the IRAF(Tody 1986, 1993) environment. The heart of the system is xcsao, which implements the cross-correlation method, and is a direct descendant of the system built by Tonry and Davis (1979). emsao uses intelligent heuristics to search for emission lines in spectra, then fits them to obtain a redshift. sumspec shifts and sums spectra to build templates for cross-correlation. linespec builds synthetic spectra given a list of spectral lines. bcvcorr corrects velocities for the motion of the earth. We discuss in detail the parameters necessary to run xcsao and emsao properly. We discuss the reliability and error associated with xcsao derived redshifts. We develop an internal error estimator, and we show how large, stable surveys can be used to develop more accurate error estimators. We develop a new methodology for building spectral templates for galaxy redshifts. We show how to obtain correlation velocities using emission line templates. Emission line correlations are substantially more efficient than the previous standard technique, automated emission line fitting. We compare the use of RVSAO with new methods, which use Singular Value Decomposition and $χ^2$ fitting techniques.
description: 42 pages, 74 figures, aastex, submitted to PASP, 13. March 1998 More info at http://tdc-www.harvard.edu/, second version with revised figures
Fluctuation-damping of isolated, oscillating Bose-Einstein condensates
Creators: name: Lappe, Tim
name: Posazhennikova, Anna
name: Kroha, Johann
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Experiments on the nonequilibrium dynamics of an isolated Bose-Einstein condensate (BEC) in a magnetic double-well trap exhibit a puzzling divergence: While some show dissipation-free Josephson oscillations, others find strong damping. Such damping in isolated BECs cannot be understood on the level of the coherent Gross-Pitaevskii dynamics. Using the Keldysh functional-integral formalism, we describe the time-dependent system dynamics by means of a multi-mode BEC coupled to fluctuations (single-particle excitations) beyond the Gross-Pitaevskii saddle point. We find that the Josephson oscillations excite an excess of fluctuations when the effective Josephson frequency, $\tildeω_J$, is in resonance with the effective fluctuation energy, $\tilde{\varepsilon}_m$, where both, $\tildeω_J$ and $\tilde{\varepsilon}_m$, are strongly renormalized with respect to their noninteracting values. Evaluating and using the model parameters for the respective experiments describes quantitatively the presence or absence of damping.
description: Phys Rev. A, published version, display of some figures improved, references corrected. 12 pages, 7 figures
NAP –2018 conference program (Zatoka, Ukraine, September 9–14, 2018)
Creators: name: Koman, Bohdan
name: R. Skrynkovskyy
name: Yuzevych, Volodymyr
Publisher: name: figshare
Year: 2018
Subjects: subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: NAP –2018 conference program. (2018). 2018 IEEE 8th International Conference on Nanomaterials: Applications & Properties (NAP – 2018).
Acarus holosericeus Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Acaridae
Acarus
Acarus holosericeus

description: Acarus holosericeus [spec. nov.]
A. abdomine depresso tomentoso postice retuso, terrestris. Fn. svec. 1200.
It. oel. 84.
List. aran. f. 38.
Raj. ins. 41. n. 38.
Blank. ins t. 14. f. J.
Habitat in Europae & Americae siccis.
Simillimus praecedenti.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 617, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Additional file 8: of A novel R2R3-MYB from grape hyacinth, MaMybA, which is different from MaAN2, confers intense and magenta anthocyanin pigmentation in tobacco
Creators: name: Chen, Kaili
name: Du, Lingjuan
name: Liu, Hongli
name: Liu, Yali
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Table S1. Primers used in this study. (DOCX 22 kb)
Geometrical Origin of Tricritical Points of various U(1) Lattice Models
Creators: name: Janke, W.
name: Kleinert, H.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We review the dual relationship between various compact U(1) lattice models and Abelian Higgs models, the latter being the disorder field theories of line-like topological excitations in the systems. We point out that the predicted first-order transitions in the Abelian Higgs models (Coleman-Weinberg mechanism) are, in three dimensions, in contradiction with direct numerical investigations in the compact U(1) formulation since these yield continuous transitions in the major part of the phase diagram. In four dimensions, there are indications from Monte Carlo data for a similar situation. Concentrating on the strong-coupling expansion in terms of geometrical objects, surfaces or lines, with certain statistical weights, we present semi-quantitative arguments explaining the observed cross-over from first-order to continuous transitions by the balance between the lowest two weights (``2:1 ratio'') of these geometrical objects.
description: LaTeX and figure files, http://www.physik.fu-berlin.de/kleinert.html