The Concise Guide to Pharmacology 2021/22: Introduction and Other Protein Targets
Creators: name: Alexander, Stephen Ph
name: Kelly, Eamonn
name: Mathie, Alistair
name: Peters, John A
name: Veale, Emma L
name: Armstrong, Jane F
name: Faccenda, Elena
name: Harding, Simon D
name: Pawson, Adam J
name: Southan, Christopher
name: Buneman, O Peter
name: Cidlowski, John A
name: Christopoulos, Arthur
name: Davenport, Anthony P
name: Fabbro, Doriano
name: Spedding, Michael
name: Striessnig, Jörg
name: Davies, Jamie A
name: Ahlers-Dannen, Katelin E
name: Alqinyah, Mohammed
name: Arumugam, Thiruma
name: Bodle, Christopher
name: Dagner, Josephine Buo
name: Chakravarti, Bandana
name: Choudhuri, Shreoshi P
name: Druey, Kirk M
name: Fisher, Rory A
name: Gerber, Kyle J
name: Hepler, John R
name: Hooks, Shelley B
name: Kantheti, Havish S
name: Karaj, Behirda
name: Layeghi-Ghalehsoukhteh, Somayeh
name: Lee, Jae-Kyung
name: Luo, Zili
name: Martemyanov, Kirill
name: Mascarenhas, Luke D
name: McNabb, Harrison
name: Montañez-Miranda, Carolina
name: Ogujiofor, Osita
name: Phan, Hoa
name: Roman, David L
name: Shaw, Vincent
name: Sjogren, Benita
name: Sobey, Christopher
name: Spicer, Mackenzie M
name: Squires, Katherine E
name: Sutton, Laurie
name: Wendimu, Menbere
name: Wilkie, Thomas
name: Xie, Keqiang
name: Zhang, Qian
name: Zolghadri, Yalda
Publisher: name: La Trobe
Year: 2021
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3214
subject: Pharmacology and pharmaceutical sciences

description: The Concise Guide to Pharmacology 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15537. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are six areas of focus: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.