cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Functionalized Germanene as a Prototype of Large-Gap Two-Dimensional Topological Insulators
Creators: name: Si, Chen
name: Liu, Junwei
name: Xu, Yong
name: Wu, Jian
name: Gu, Bing-Lin
name: Duan, Wenhui
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We propose new two-dimensional (2D) topological insulators (TIs) in functionalized germanenes (GeX, X=H, F, Cl, Br or I) using first-principles calculations. We find GeI is a 2D TI with a bulk gap of about 0.3 eV, while GeH, GeF, GeCl and GeBr can be transformed into TIs with sizeable gaps under achievable tensile strains. A unique mechanism is revealed to be responsible for large topologically-nontrivial gap obtained: owing to the functionalization, the $σ$ orbitals with stronger spin-orbit coupling (SOC) dominate the states around the Fermi level, instead of original $π$ orbitals with weaker SOC; thereinto, the coupling of the $p_{xy}$ orbitals of Ge and heavy halogens in forming the $σ$ orbitals also plays a key role in the further enlargement of the gaps in halogenated germanenes. Our results suggest a realistic possibility for the utilization of topological effects at room temperature.
Electronic stopping power of hydrogen in a high-k material at the stopping maximum and below
Creators: name: Primetzhofer, Daniel
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Electronic energy loss of hydrogen ions in HfO2 was investigated in a wide energy range in the medium and low energy ion scattering regime. Experiments by Time-Of-Flight Medium-Energy Ion Scattering (TOF-MEIS) with proton and deuteron projectiles were performed in backscattering geometry for nm-films of HfO2 on Si with an ultrathin SiO2 interface layer prepared by ALD. At energies around the stopping maximum excellent agreement is found with earlier results from Behar et al. (Phys. Rev. A 80 (2009) 062901) and theoretical predictions. Towards lower energies discrepancies between experiment and calculations increase slightly. The low energy data exhibits excellent velocity proportionality and indicates the absence of clear effects due to distinct electronic states. Thus, also no apparent velocity threshold can be predicted within the experiments uncertainty from the present data. The magnitude of the energy loss is discussed in terms of a free-electron model and compared with the expected electron densities from plasmon frequencies.
Particle Spectroscopy of Supersymmetric SU(5) in Light of 125 GeV Higgs and Muon g-2 Data
Creators: name: Okada, Nobuchika
name: Raza, Shabbar
name: Shafi, Qaisar
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The discovery of the Higgs boson at the Large Hadron Collider (LHC) has a great impact on the minimal supersymmetric extension of the Standard Model (MSSM). In the context of the constrained MSSM (CMSSM) and its extension with non-universal masses for the MSSM Higgs doublets (NUHM2), sparticles with masses $ > 1$ TeV are necessary to reproduce the observed Higgs boson mass of 125-126 GeV. On the other hand, there appears to be a significant amount of discrepancy between the measured muon $g-2$ and the Standard Model prediction. A successful explanation of this discrepancy in the MSSM requires new contributions involving relatively light sparticles with masses $ < 1$ TeV. In this paper, we attempt to accommodate the two conflicting requirements in an SU(5) inspired extension of the CMSSM. We assign non-universal but flavor blind soft supersymmetry breaking masses to the scalar components in $\bar 5$ and 10 matter supermultiplets. The two MSSM Higgs doublets in the 5, $\bar5$ representations of SU(5) are also assigned unequal soft mass$^2$ at $M_{GUT}$. We identify parameter regions which can simultaneously accommodate the observed Higgs boson mass and the muon $g-2$ data, and which are compatible with other phenomenological constraints such as neutralino dark matter relic abundance and rare B-meson decays. Some regions of the allowed parameter space will be explored at the upgraded LHC and by dark matter direct detection experiments.
description: 34 pages, 26 figures, 1 table
Dynamics and Stability of Chiral Fluid
Creators: name: Mishustin, Igor N.
name: Koide, Tomoi
name: Denicol, Gabriel S.
name: Torrieri, Giorgio
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Starting from the linear sigma model with constituent quarks we derive the chiral fluid dynamics where hydrodynamic equations for the quark fluid are coupled to the equation of motion for the order-parameter field. In a static system at thermal equilibrium this model leads to a chiral phase transition which, depending on the choice of the quark-meson coupling constant, could be a crossover or a first order one. We investigate the stability of the chiral fluid in the static and expanding backgrounds by considering the evolution of perturbations with respect to the mean-field solution. In the static background the spectrum of plane-wave perturbations consists of two branches, one corresponding to the sound waves and another to the sigma-meson excitations. For large couplings these two branches "cross" and the excitation spectrum acquires exponentially growing modes. The stability analysis is also done for the Bjorken-like background solution by explicitly solving the time-dependent differential equation for perturbations in the eta-space. In this case the growth rate of unstable modes is significantly reduced.
description: 29 pages, 10 figures, to be published in the special issue of "Physics of Atomic Nuclei" dedicated to 90-th birthday of Prof. Spartak Belyaev
Running Couplings in Quantum Theory of Gravity Coupled with Gauge Fields
Creators: name: Narain, Gaurav
name: Anishetty, Ramesh
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper we study the coupled system of non-abelian gauge fields with higher-derivative gravity. Charge renormalization is investigated in this coupled system. It is found that the leading term in the gauge coupling beta function comes due to interaction of gauge fields with gravitons. This is shown to be a universal quantity in the sense that it doesn't depend on the gauge coupling and the gauge group, but may depend on the other couplings of the action (gravitational and matter). The coupled system is studied at one-loop. It is found that the leading term of gauge beta function is zero at one-loop in four dimensions. The effect of gauge fields on the running of gravitational couplings is investigated. The coupled system of gauge field with higher-derivative gravity is shown to satisfy unitarity when quantum corrections are taken in to account. Moreover, it is found that Newton constant goes to zero at short distances. In this renormalizable and unitary theory of gauge field coupled with higher-derivative gravity, the leading term of the gauge beta function, found to be universal for all gauge groups, is further studied in more detail by isolating it in the context of abelian gauge theories coupled with gravity in four dimensions. Using self-duality of abelian gauge theories in four dimensions, this term of the gauge beta function is shown to be zero to all loops. This is found to be independent of the gravity action, regularization scheme and gauge fixing condition. An explicit one-loop computation for arbitrary gravity action further demonstrates the vanishing of this term in the gauge beta function in four dimensions, independent of the regularization scheme and gauge fixing condition. Consequences of this are discussed.
description: 1+42 pages, 7 figures
Receiver operating characteristic analysis of acoustic and electroglottographic parameters with different sustained vowels
Creators: name: Yılmaz, Göksu
name: Cangi, M. Emrah
name: Yelken, Kürşat
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: To examine the power of the parameters obtained from different sustained vowels used in acoustic and electroglottographic (EGG) voice evaluation protocols to discriminate between dysphonic and non-dysphonic voice quality. Sixty non-dysphonic participants and 30 dysphonic participants were included in the study. In addition to the time domain amplitude and frequency perturbation parameters obtained from the sustained phonation of /ʌ/-/ɛ/-/i/-/u/ vowels, several frequency-domain spectral/cepstral parameters and EGG parameters were evaluated. The classification performance of the acoustic and electroglottographic measures was quantified using analysis and receiver operating characteristic (ROC) curve analysis. As a result of ROC analysis, the discriminative diagnostic performance (area under the curve, AUC) of the test for low-vowel (/ʌ/-/ɛ/) phonation was higher than values obtained from high-vowel (/i/-/u/) phonation. For /ʌ/ and /ɛ/ sustained vowels, the parameters exhibiting the highest discrimination were fundamental frequency standard deviation (fo/STD), cepstral peak prominence (CPP), relative average perturbation (RAP), pitch perturbation quotient (PPQ), and jitter percent (JITT). In the EGG parameters, on the other hand, average jitter and periodicity parameters obtained from front vowels (/ɛ/-/i/) were found to have higher AUC values compared to back vowels (/ʌ/-/u/). In acoustic analyses, /ʌ/ and /ɛ/ sustained vowels give the highest diagnostic performance. In the electroglottographic evaluation, on the other hand, /ɛ/ and /i/ vowels, when the position of the tongue is forward, have better classification performance compared to /ʌ/ and /u/ vowels, when the position of the tongue is back.
Receiver operating characteristic analysis of acoustic and electroglottographic parameters with different sustained vowels
Creators: name: Yılmaz, Göksu
name: Cangi, M. Emrah
name: Yelken, Kürşat
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: To examine the power of the parameters obtained from different sustained vowels used in acoustic and electroglottographic (EGG) voice evaluation protocols to discriminate between dysphonic and non-dysphonic voice quality. Sixty non-dysphonic participants and 30 dysphonic participants were included in the study. In addition to the time domain amplitude and frequency perturbation parameters obtained from the sustained phonation of /ʌ/-/ɛ/-/i/-/u/ vowels, several frequency-domain spectral/cepstral parameters and EGG parameters were evaluated. The classification performance of the acoustic and electroglottographic measures was quantified using analysis and receiver operating characteristic (ROC) curve analysis. As a result of ROC analysis, the discriminative diagnostic performance (area under the curve, AUC) of the test for low-vowel (/ʌ/-/ɛ/) phonation was higher than values obtained from high-vowel (/i/-/u/) phonation. For /ʌ/ and /ɛ/ sustained vowels, the parameters exhibiting the highest discrimination were fundamental frequency standard deviation (fo/STD), cepstral peak prominence (CPP), relative average perturbation (RAP), pitch perturbation quotient (PPQ), and jitter percent (JITT). In the EGG parameters, on the other hand, average jitter and periodicity parameters obtained from front vowels (/ɛ/-/i/) were found to have higher AUC values compared to back vowels (/ʌ/-/u/). In acoustic analyses, /ʌ/ and /ɛ/ sustained vowels give the highest diagnostic performance. In the electroglottographic evaluation, on the other hand, /ɛ/ and /i/ vowels, when the position of the tongue is forward, have better classification performance compared to /ʌ/ and /u/ vowels, when the position of the tongue is back.
Experimental Measurements of Ion Diffusion Coefficients and Heating in a Multi-Ion-Species Plasma Shock
Creators: name: Chu, F.
name: LaJoie, A. L.
name: Keenan, B. D.
name: Webster, L.
name: Langendorf, S. J.
name: Gilmore, M. A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Collisional plasma shocks generated from supersonic flows are an important feature in many astrophysical and laboratory high-energy-density plasmas. Compared to single-ion-species plasma shocks, plasma shock fronts with multiple ion species contain additional structure, including interspecies ion separation driven by gradients in species concentration, temperature, pressure, and electric potential. We present time-resolved density and temperature measurements of two ion species in collisional plasma shocks produced by head-on merging of supersonic plasma jets, allowing determination of the ion diffusion coefficients. Our results provide the first experimental validation of the fundamental inter-ion-species transport theory. The temperature separation, a higher-order effect reported here, is valuable for advancements in modeling HED and ICF experiments.
description: 6 pages, 4 figures, 1 table
The Role of a Flux Rope Ejection in Three-dimensional Magnetohydrodynamic Simulation of a Solar Flare
Creators: name: Nishida, Keisuke
name: Nishizuka, Naoto
name: Shibata, Kazunari
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: We investigated the dynamic evolution of a 3-dimensional (3D) flux rope eruption and magnetic reconnection process in a solar flare, by simply extending 2-dimensional (2D) resistive magnetohydrodynamic simulation model of solar flares with low $β$ plasma to 3D model. We succeeded in reproducing a current sheet and bi-directional reconnection outflows just below the flux rope during the eruption in our 3D simulations. We calculated four cases of a strongly twisted flux rope and a weakly twisted flux rope in 2D and 3D simulations. The time evolution of a weakly twisted flux rope in 3D simulation shows similar behaviors to 2D simulation, while a strongly twisted flux rope in 3D simulation shows clearly different time evolution from 2D simulation except for the initial phase evolution. The ejection speeds of both strongly and weakly twisted flux ropes in 3D simulations are larger than 2D simulations, and the reconnection rates in 3D cases are also larger than 2D cases. This indicates a positive feedback between the ejection speed of a flux rope and the reconnection rate even in the 3D simulation, and we conclude that the plasmoid-induced reconnection model can be applied to 3D. We also found that small scale plasmoids are formed inside a current sheet and make it turbulent. These small scale plasmoid ejections has role in locally increasing reconnection rate intermittently as observed in solar flares, coupled with a global eruption of a flux rope.
description: Accepted by ApJL, August 1, 2013
A categorical characterization of strong Steiner $ω$-categories
Creators: name: Ara, Dimitri
name: Gagna, Andrea
name: Ozornova, Viktoriya
name: Rovelli, Martina
Publisher: name: arXiv
Year: 2022
Subjects: subject: Category Theory (math.CT)
subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 18N30, 18G35

description: Strong Steiner $ω$-categories are a class of $ω$-categories that admit algebraic models in the form of chain complexes, whose formalism allows for several explicit computations. The conditions defining strong Steiner $ω$-categories are traditionally expressed in terms of the associated chain complex, making them somewhat disconnected from the $ω$-categorical intuition. The purpose of this paper is to characterize this class as the class of polygraphs that satisfy a loop-freeness condition that does not make explicit use of the associated chain complex and instead relies on the categorical features of $ω$-categories.
description: 27 pages, v2: final version
Additional file 1 of Two novel mutations in the DNAH11 gene in primary ciliary dyskinesia (CILD7) with considerable variety in the clinical and beating cilia phenotype
Creators: name: Schultz, Rüdiger
name: Elenius, Varpu
name: Lukkarinen, Heikki
name: Saarela, Tanja
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1. PICADAR Questionnaire after Behan et al. [12].
The extrema of an action principle for dissipative mechanical systems
Creators: name: Lin, Tongling
name: Wang, Qiuping A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: A least action principle for damping motion has been previously proposed with a Hamiltonian and a Lagrangian containing the energy dissipated by friction. Due to the space-time nonlocality of the Lagrangian, mathematical uncertainties persist about the appropriate variational calculus and the nature (maxima, minima and inflection) of the stationary action. The aim of this work is to make numerical simulation of damped motion and to compare the actions of different paths in order to get evidence of the existence and the nature of stationary action. The model is a small particle subject to conservative and friction forces. Two conservative forces and three friction forces are considered. The comparison of the actions of the perturbed paths with that of the Newtonian path reveals the existence of extrema of action which are minima for zero or very weak friction and shift to maxima when the motion is overdamped. In the intermediate case, the action of the Newtonian path is neither least nor most, meaning that the extreme feature of the Newtonian path is lost. In this situation, however, no reliable evidence of stationary action can be found from the simulation result.
description: 22 pages, 8 figures, accepted by J. Appl. Mech (2013)
Villa Lioy 1864
Creators: name: Greathead, David J.
name: Karimpour, Younes
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Bombyliidae
Villa

description: Genus Villa Lioy, 1864
 The genus Villa is one of the largest and most widespread genera of Bombyliidae with more than 250 species on all continents except Antarctica and on many oceanic islands (Evenhuis & Greathead, 1999, 2003). It belongs to the tribe Villini within the subfamily Anthracinae (keys to genera in Greathead & Evenhuis, 1997, 2001). It is characterised by having a rounded, not prominent face; antenna with only one flagellomere; a relatively elongate parallel­sided body with a pattern of black, brown and yellow or whitish vestiture; usually with a well developed patagium; wing hyaline or with a simple basicostal infuscation; male genitalia with a large tongue­shaped epiphallus often bearing a pair of apical spines. The Palaearctic fauna includes several species groups with different structure of the epiphallus, first noted by François (1969). He noted that many species from Asia have a compact body, predominantly pale whitish vestiture and fine spicules on the epiphallus. The present species has these characteristics. It is similar in appearance to V. niphobleta Loew, described from Greece and known from France and Tunisia eastwards to Afghanistan, which has the coloration of the Asiatic species group but an epiphallus similar to the majority of European species with apical spines and without spicules.
description: Published as part of Greathead, David J. & Karimpour, Younes, 2006, A new species of Villa Lioy, 1864 (Diptera: Bombyliidae) parasitic on Sesiidae (Lepidoptera), pp. 65-68 in Zootaxa 1156 on page 66, DOI: 10.5281/zenodo.172263
Warm inflation in presence of magnetic fields
Creators: name: Piccinelli, Gabriella
name: Sanchez, Angel
name: Ayala, Alejandro
name: Mizher, Ana Julia
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present preliminary results on the possible effects that primordial magnetic fields can have for a warm inflation scenario, based on global supersymmetry, with a new-inflation-type potential. This work is motivated by two considerations: first, magnetic fields seem to be present in the universe on all scales, which rises the possibility that they could also permeate the early universe; second, the recent emergence of inflationary models where the inflaton is not assumed to be isolated but instead it is taken as an interacting field, even during the inflationary expansion. The effects of magnetic fields are included resorting to Schwinger proper time method.
description: Published in AIP Conf. Proc. 1548, 288 (2013), IX Mexican School on Gravitation and Mathematical Physics: Cosmology for the XXIst Century
Revisiting loss-specific training of filter-based MRFs for image restoration
Creators: name: Chen, Yunjin
name: Pock, Thomas
name: Ranftl, René
name: Bischof, Horst
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: It is now well known that Markov random fields (MRFs) are particularly effective for modeling image priors in low-level vision. Recent years have seen the emergence of two main approaches for learning the parameters in MRFs: (1) probabilistic learning using sampling-based algorithms and (2) loss-specific training based on MAP estimate. After investigating existing training approaches, it turns out that the performance of the loss-specific training has been significantly underestimated in existing work. In this paper, we revisit this approach and use techniques from bi-level optimization to solve it. We show that we can get a substantial gain in the final performance by solving the lower-level problem in the bi-level framework with high accuracy using our newly proposed algorithm. As a result, our trained model is on par with highly specialized image denoising algorithms and clearly outperforms probabilistically trained MRF models. Our findings suggest that for the loss-specific training scheme, solving the lower-level problem with higher accuracy is beneficial. Our trained model comes along with the additional advantage, that inference is extremely efficient. Our GPU-based implementation takes less than 1s to produce state-of-the-art performance.
description: 10 pages, 2 figures, appear at 35th German Conference, GCPR 2013, Saarbr\"ucken, Germany, September 3-6, 2013. Proceedings
Additional file 1 of Preparedness and response activities of the US Department of Veterans Affairs (VA) home-based primary care program around the fall 2017 hurricane season
Creators: name: Wyte-Lake, Tamar
name: Der-Martirosian, Claudia
name: Chu, Karen
name: Johnson-Koenke, Rachel
name: Dobalian, Aram
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: Additional file 1: Supplementary file 1. Fall 2017 Hurricanes Interview Guide. Semi-structured interview guide to guide data collection.
Bunches of Random Cross-correlated Sequences
Creators: name: Maystrenko, A. A.
name: Melnik, S. S.
name: Pritula, G. M.
name: Usatenko, O. V.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Statistical properties of random cross-correlated sequences constructed by the convolution method (likewise referred to as the Rice's or the inverse Fourier transformation) are examined. Algorithms for their generation are discussed. They are frequently reduced to solving the problem for decomposition of the Fourier transform of the correlation matrix into a product of two mutually conjugate matrices; different decompositions of the correlation matrix are considered. The limits of weak and strong correlations for the one-point probability and pair correlation functions of the sequences are studied. Special cases of heavy-tailed distributions resulting from the convolution generation are analyzed. Anisotropic properties of statistically homogeneous random sequences related to asymmetry of a filtering function are discussed.
description: 20 pages, 1 figure
Structure–activity relationships study of N-ethylene glycol-comprising alkyl heterocyclic carboxamides against A549 lung cancer cells
Creators: name: Ohta, Kaito
name: Ii, Hiromi
name: Takahashi, Mei
name: Moyama, Chiami
name: Ando, Shota
name: Mori, Masaya
name: Masuda, Maho
name: Nambu, Hisanori
name: Nakata, Susumu
name: Kojima, Naoto
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Aim: Certain cancer cells depend on oxidative phosphorylation for survival; thus, inhibiting this process may be a promising treatment strategy. This study explored the structure–activity relationships of the mitochondrial inhibitor N-ethylene glycol-comprising alkyl thiophene-3-carboxamide 3. Methods & results: We synthesized and evaluated 13 analogs (5a–m) with different ethylene glycol units, heterocycles and connecting groups for their growth-inhibitory effects on A549 non-small cell lung cancer cells. We found that increasing the number of ethylene glycol units significantly enhanced inhibitory activity. Some analogs activated adenosine monophosphate-activated protein kinase, similar to 3. Notably, analog 5e, which contains tetraethylene glycol units, significantly inhibited tumor growth in vivo. Conclusion: Analog 5 may be a potential therapeutic agent for non-small cell lung cancer treatment. This study explored the structure–activity relationships of the mitochondrial inhibitor N-ethylene glycol-comprising alkyl thiophene-3-carboxamide. We synthesized and evaluated 13 analogs with varying ethylene glycol units, heterocycles and connecting groups for their growth–inhibitory activity against A549 non-small cell lung cancer cells. Our findings indicate that increasing the number of ethylene glycol units significantly enhanced inhibitory activity. Some analogs induced phosphorylated AMP-activated protein kinase. Analog 5e, with tetraethylene glycol units, significantly inhibited tumor growth in vivo. These results suggest that analog 5 is a potential agent for non-small cell lung cancer treatment.
Additional file 1 of Can an mhealth clinical decision-making support system improve adherence to neonatal healthcare protocols in a low-resource setting?
Creators: name: Amoakoh, Hannah Brown
name: Klipstein-Grobusch, Kerstin
name: Agyepong, Irene Akua
name: Amoakoh-Coleman, Mary
name: Gbenga A. Kayode
name: J. B. Reitsma
name: Grobbee, Diederick E.
name: Ansah, Evelyn K.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1.
Experimental quantum pattern recognition in IBMQ and diamond NVs
Creators: name: Das, Sreetama
name: Zhang, Jingfu
name: Martina, Stefano
name: Suter, Dieter
name: Caruso, Filippo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: One of the most promising applications of quantum computing is the processing of graphical data like images. Here, we investigate the possibility of realizing a quantum pattern recognition protocol based on swap test, and use the IBMQ noisy intermediate-scale quantum (NISQ) devices to verify the idea. We find that with a two-qubit protocol, swap test can efficiently detect the similarity between two patterns with good fidelity, though for three or more qubits the noise in the real devices becomes detrimental. To mitigate this noise effect, we resort to destructive swap test, which shows an improved performance for three-qubit states. Due to limited cloud access to larger IBMQ processors, we take a segment-wise approach to apply the destructive swap test on higher dimensional images. In this case, we define an average overlap measure which shows faithfulness to distinguish between two very different or very similar patterns when simulated on real IBMQ processors. As test images, we use binary images with simple patterns, greyscale MNIST numbers and MNIST fashion images, as well as binary images of human blood vessel obtained from magnetic resonance imaging (MRI). We also present an experimental set up for applying destructive swap test using the nitrogen vacancy centre (NVs) in diamond. Our experimental data show high fidelity for single qubit states. Lastly, we propose a protocol inspired from quantum associative memory, which works in an analogous way to supervised learning for performing quantum pattern recognition using destructive swap test.
description: 15 pages, 15 figures
Electronic structure modification of Si-nanocrystals with F4 -TCNQ
Creators: name: Carvalho, A.
name: Coutinho, J.
name: Barroso, M.
name: Silva, E. L.
name: Oberg, S.
name: Rayson, M.
name: Briddon, P. R.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We use first-principles models to demonstrate how an organic oxidizing agent, F4 -TCNQ (7,7,8,8- tetracyano-2,3,5,6-tetrafluoroquinodimethane), modifies the electronic structure of silicon nanocrys- tals, suggesting it may enhance p-type carrier density and mobility. The proximity of the lowest unoccupied level of F4 -TCNQ to the highest occupied level of the Si-nanocrystals promotes the formation of an empty hybrid state overlapping both nanocrystal and molecule, reducing the exci- tation energy to about 0.8-1 eV in vacuum. Hence, it is suggested that F4 -TCNQ can serve both as a surface oxidant and a mediator for hole hopping between adjacent nanocrystals.
On an elastic flow for parametrized curves in $\mathbb{R}^n$ suitable for numerical purposes
Creators: name: Pozzi, Paola
Publisher: name: arXiv
Year: 2022
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: (2020): 53E40, 35K55, 35K25

description: In arXiv:2205.02920 a variant of the classical elastic flow for closed curves in $\mathbb{R}^{n}$ was introduced, that is more suitable for numerical purposes. Here we investigate the long-time properties of such evolution demonstrating that the flow exists globally in time.
description: 21 pages
Investigating the presence of 500 um submillimeter excess emission in local star forming galaxies
Creators: name: Kirkpatrick, Allison
name: Calzetti, Daniela
name: Galametz, Maud
name: Kennicutt, Rob
name: Dale, Daniel
name: Aniano, Gonzalo
name: Sandstrom, Karin
name: Armus, Lee
name: Crocker, Alison
name: Hinz, Joannah
name: Hunt, Leslie
name: Koda, Jin
name: Walter, Fabian
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Submillimeter excess emission has been reported at 500 microns in a handful of local galaxies, and previous studies suggest that it could be correlated with metal abundance. We investigate the presence of an excess submillimeter emission at 500 microns for a sample of 20 galaxies from the Key Insights on Nearby Galaxies: a Far Infrared Survey with Herschel (KINGFISH) that span a range of morphologies and metallicities (12+log(O/H)=7.8-8.7). We probe the far-infrared (IR) emission using images from the Spitzer Space Telescope and Herschel Space Observatory in the wavelength range 24-500 microns. We model the far-IR peak of the dust emission with a two-temperature modified blackbody and measure excess of the 500 micron photometry relative to that predicted by our model. We compare the submillimeter excess, where present, with global galaxy metallicity and, where available, resolved metallicity measurements. We do not find any correlation between the 500 micron excess and metallicity. A few individual sources do show excess (10-20%) at 500 microns; conversely, for other sources, the model overpredicts the measured 500 micron flux density by as much as 20%, creating a 500 micron "deficit". None of our sources has an excess larger than the calculated 1-sigma uncertainty, leading us to conclude that there is no substantial excess at submillimeter wavelengths at or shorter than 500 microns in our sample. Our results differ from previous studies detecting 500 micron excess in KINGFISH galaxies largely due to new, improved photometry used in this study.
description: 12 pages, 8 figures. Accepted for publication in ApJ
Літературні Кліше та Ера Революцій
Creators: name: Serhii Yaremko
Publisher: name: Zenodo
Year: 2023
Subjects: Literary clichés
Movie clichés

description: Це український оригінал мого есе. Я опублікував його спеціально для громадян України. It's the Ukrainian version of the essay of mine, I have published it for the citizens of Ukraine.
description: Дана робота не публікувалася в жодному журналі
The influence of the matter along the line of sight and in the lens environment on the strong gravitational lensing
Creators: name: Jaroszynski, M.
name: Kostrzewa-Rutkowska, Z.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We investigate the influence of the matter along the line of sight and in the lens environment on the image configurations, relative time delays, and the resulting models of strong gravitational lensing. The distribution of matter in space and properties of gravitationally bound haloes are based on the Millennium Simulation. In our numerical experiments we consider isolated lens in a uniform universe model and the same lens surrounded by close neighbours and/or objects close to the line of sight which gives four different descriptions of the light propagation. We compare the results of the lens modeling which neglects effects of the environment and line of sight, when applied to image configurations resulting from approaches partially or fully taking into account these effects. We show that for a source at the redshift z=2 the effects are indeed important and may prevent successful fitting of lens models in a substantial part of simulated image configurations, especially when the relative time delays are taken into account. To have good constraints on the models we limit ourselves to configurations of four images. We consider eighty lenses and large number of source positions in each case. The influence of the lens neighbourhood and the line of sight introduces the spread into the fitted values of the deflection angles which translates into the spread in the lens velocity dispersion of 4 per cent. Similarly for the lens axis ratio we get the spread of 10 per cent and for the Hubble's constant of 6 per cent. When averaged over all lenses and all image configurations considered, the median fitted values of the parameters (including the Hubble's constant) do not differ more than 1 per cent from their values used in simulations.
description: 10 pages, 8 figures
Additional file 2 of Malaria during pregnancy and transplacental transfer of Kaposi sarcoma-associated herpesvirus (KSHV) antibodies: a cohort study of Kenyan mother and child pairs
Creators: name: Sabourin, Katherine R.
name: Ogolla, Sidney
name: Daud, Ibrahim I.
name: Jackson, Conner L.
name: Miley, Wendell
name: Labo, Nazzarena
name: Whitby, Denise
name: Rochford, Rosemary
Publisher: name: figshare
Year: 2020
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. Relationship between maternal Kaposi sarcoma-associated herpesvirus (KSHV) antibody levels at delivery and malaria infection during pregnancy.
Critical reagent considerations for immunogenicity assay development for bispecific biotherapeutic candidates
Creators: name: Sinha, Arkadeep
name: Rinker, Sherri
name: Souliotis, Mallory Rose
name: Kumar, Rajesh
name: Kumar, Seema
name: Cowan, Kyra J
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Aim: To demonstrate the importance of critical reagent characterization for immunogenicity assay development for multi-specific drugs using two case studies. Methods: Bridging anti-drug antibody (ADA) assay with acid-dissociated samples were used for both cases. Results: In the first case study, the unexpected interference in an ADA assay from clinical samples was identified; a model was created to replicate the issue, and an anti-target antibody was identified to mitigate the target interference. In the second case study, an issue due to non-specific binding of a domain-specific confirmatory reagent was identified, and various mitigation techniques were evaluated. Conclusion: A thorough characterization of the critical reagents helped identify the issues with these ADA case studies and provided strategies for resolving them. When drugs involve heavily glycosylated targets, an in-study cut point may be more prudent. Geographical differences, stage of progression of disease may affect the target glycosylation impacting its affinity for the drug, eventually impacting the cut point. Given the unknowns of sample purification impact, patient-derived purified heterogenous targets may not always be the gold standard for target interference assessments in an ADA assay. Homogenous recombinant targets whose sequences have been verified may perform better in replicating target interference issues observed with patient samples. Bispecific biologics require additional critical reagents to support immunogenicity assessments like domain-specific confirmatory reagents which may require additional characterization at the bioanalytical laboratory. Utilizing an optimal concentration of the sample serum could be an alternative to adding serum for blocking non-specific binding in an ADA assay. Assay sensitivity and drug tolerance are key factors to test when utilizing this method.
On the Interval [n,2n]: Primes, Composites and Perfect Powers
Creators: name: Paz, Germán
Publisher: name: arXiv
Year: 2013
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 00-XX, 00A05, 11-XX, 11A41

description: In this paper we show that for every positive integer $n$ there exists a prime number in the interval $[n,9(n+3)/8]$. Based on this result, we prove that if $a$ is an integer greater than 1, then for every integer $n>14.4a$ there are at least four prime numbers $p$, $q$, $r$, and $s$ such that $n14.4/(|\sqrt[m]{1.5}|-1)^m$ there exist a positive integer $a$ and a prime number $s$ such that $n14.4/(|\sqrt[m]{2}|-|\sqrt[m]{1.5}|)^m$ there exist a prime number $r$ and a positive integer $a$ such that $n
description: 15 pages, 2 tables
Additional file 1 of Comparing generations of migrants’ transnational behaviour: the role of the transnational convoy and integration
Creators: name: Klok, Jolien
name: Tilburg, Theo Van
name: Fokkema, Tineke
name: Suanet, Bianca
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 1. Supplementary Material.
Representability Conditions by Grassmann Integration
Creators: name: Bach, Volker
name: Knörr, Hans Konrad
name: Menge, Edmund
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: 81V70

description: Representability conditions on the one- and two-particle density matrix for fermion systems are formulated by means of Grassmann integrals. A positivity condition for a certain kind of Grassmann integral is established which, in turn, induces the well-known G-, P- and Q-Conditions of quantum chemistry by an appropriate choice of the integrand. Similarly, the T1- and T2-Conditions are derived. Furthermore, quasifree Grassmann states are introduced and it is shown that every so-called generalized one-particle density matrix which is bounded between 0 and 1 corresponds to a unique quasifree Grassmann state.
Border mapping multi-resolution (BMMR) technique for incompressible projection-based particle methods
Creators: name: Bellezi, Cezar Augusto
name: Cheng, Liang-Yee
name: Junior, Rubens Augusto Amaro
name: Tsukamoto, Marcio Michiharu
Publisher: name: arXiv
Year: 2022
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: A novel multi-resolution technique called border mapping multi-resolution (BMMR) is proposed for projection-based particle methods. The BMMR aims to obtain background equivalent particle distributions in the two sides of a border between sub-domains with a 2:1 resolution ratio so that a single resolution framework is adopted to near-border particles calculations. The novelty of the BMMR is that it obtains the background grid from the mapping of the actual particle distribution in the border and, as a result, the location of the particles in the background grid exactly matches the location of the actual particles. In this way, such technique aims to reduce the error from the interpolation of the physical quantities in the background grid and to avoid sudden changes in the particle distribution that may lead to unstable local pressure calculation. In the coarse side of the border, the refinement is made by a triangulation and by placing fictitious particles in the midpoints of the triangles. In the fine side of the border, the derefinement is made by defining a set of fine particles that result in a particle distribution that best resembles a coarse one. The accuracy and computational performance of the BMMR implemented in a moving particle semi-implicit (MPS) simulation system are verified by using benchmark test cases of 2D free surface flows.
description: 58 pages, 21 figures
Additional file 3 of Malaria during pregnancy and transplacental transfer of Kaposi sarcoma-associated herpesvirus (KSHV) antibodies: a cohort study of Kenyan mother and child pairs
Creators: name: Sabourin, Katherine R.
name: Ogolla, Sidney
name: Daud, Ibrahim I.
name: Jackson, Conner L.
name: Miley, Wendell
name: Labo, Nazzarena
name: Whitby, Denise
name: Rochford, Rosemary
Publisher: name: figshare
Year: 2020
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 3. Linear regression estimates of mean difference in KSHV antibody log(CMR) by malaria exposure.
Bioanalysis of free antisense oligonucleotide payload from antibody–oligonucleotide conjugate by hybridization LC-MS/MS
Creators: name: Jiang, Di
name: Li, Pei
name: Yuan, Long
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Virology
subject: Computational Biology

description: Background: Antisense oligonucleotides (ASOs) have been conjugated to various moieties, such as peptides, antibodies or Fab regions of antibodies, to enhance their delivery to target tissues. The quantitation of free ASO (ASO payload) is critical to characterize its pharmacokinetics/pharmacodynamics (PK/PD) properties and biodistribution after delivery of the peptide/antibody/Fab ASO conjugates. Results: We developed a hybridization-based LC-MS/MS methodology for quantification of free ASO in tissues in the presence of Fab–ASO and ASO with linker (ASO-linker). Conclusion: The developed method was applied to measure accurately the free ASO concentrations in liver and gastrocnemius in mice that were dosed with Fab-ASO. This methodology has also been applied to free ASO bioanalysis for other antibody-ASO and Fab-ASO conjugates in various tissues and plasma/serum samples. Antisense oligonucleotides (ASOs) have been conjugated to various moieties, such as antibodies or Fab regions of antibodies, to enhance their delivery to target tissues. Accurate and reliable quantitation of free ASO (ASO payload) from antibody–ASO or Fab–ASO conjugates is critical to characterize its pharmacokinetics/pharmacodynamics properties and biodistribution after delivery of the antibody/Fab ASO conjugates. The interference of Fab–ASO and ASO-linker to free ASO quantitation was evaluated and minimized by selecting a proper MRM transition. Hybridization extraction did not cause any significant degradation or conversion of Fab–ASO1 to ASO1 or ASO1-linker. Minimal (0.1%) conversion from Fab–ASO1 to ASO1 may happen during the proteinase K digestion step. The proteinase K digestion step in the sample preparation was removed to avoid the interferences caused by digestion of Fab–ASO or ASO-linker. Satisfactory recovery of free ASO was achieved in plasma and tissue homogenate (tenfold homogenization with buffer) without the proteinase K digestion step. The study reported the first LC-MS/MS bioanalytical method for the quantification of free ASO payload from Fab-ASO conjugates. The developed LC-MS/MS method is ready to quantify free ASOs from Fab–ASOs or antibody–oligonucleotide conjugates in various biological matrices.