cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
History of the Mormon missionary movement in South America to 1940
Creators: name: Peterson, John Delon
Publisher: name: University of Utah
Year: 2014
Subjects: Church of Jesus Christ of Latter-Day Saints
Mormons
Missionaries
South America
Proselyting

description: religious thought and practice that is American in origin. From a beginning in western New York in 1830 it has grown into an organization which is worldwide in scope. Those largely responsible for this expansion are Mormon missionaries- members of the Church who devote two to three years in voluntary proselyting service in the interest of their faith. In many ways the missionary system has become one of Mormonism's most powerful institutions. This study will trace the history of Mormon missionary expansion into South America up to 1940. The term South America in this thesis designates primarily the area of Brazil and Argentina. This is where the first significant Mormon advances were made in this part of the world. Chile is mentioned in the early chapters and other South American countries are discussed as Mormons came in contact with them. Throughout the chapters of this thesis the author has attempted to illustrate not only the growth of the Mormon church, but also the proselyting methods, procedures, mission policies and particular problems that have faced the missionaries during the years when Mormonism was struggling to gain a foothold in South America. Chapter III, giving the religious background in Argentina and Brazil, was written for the purpose of helping the reader visualize the e c c l e s i a s tical atmosphere in which Mormonism was established. The chief sources of material for this study have been books and periodicals published by the Mormon church, letters of missionaries, quarterly historical reports V and financial and statistical reports from the missions, autobiographies, journals, mission publications and private interviews with former missionaries to Brazil and Argentina. This study includes no data concerning the members of the Church in South America, how they were converted to this American religion or their problems in accepting its doctrine and staying true to it. It has not been possible to get any source material which would illustrate a view of the Mormon church through the eyes of a Brazilian or an Argentinean. Because few Mormons have emigrated to the United States from the missions of the Church in South America there are no available journals, diaries or documents of these emigrants which describe the reactions of those who have been the recipients of this proselyting expansion. This study, therefore, is limited to the North American Mormon missionaries' view of their own activities. In this thesis, the Church of Jesus Christ of Latter-day Saints is referred to frequently as "the Church. " This is done for the purpose of avoiding the use of this long proper name or the repetition of the word "Mormon. "
A numerically stable algorithm for integrating Bayesian models using Markov melding
Creators: name: Manderson, Andrew
name: Goudie, Robert
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
Biased sampling
Data integration
Evidence synthesis
Kernel density estimation
Multi-source inference
Self-density ratio
Weighted sampling

description: AbstractWhen statistical analyses consider multiple data sources, Markov melding provides a method for combining the source-specific Bayesian models. Markov melding joins together submodels that have a common quantity. One challenge is that the prior for this quantity can be implicit, and its prior density must be estimated. We show that error in this density estimate makes the two-stage Markov chain Monte Carlo sampler employed by Markov melding unstable and unreliable. We propose a robust two-stage algorithm that estimates the required prior marginal self-density ratios using weighted samples, dramatically improving accuracy in the tails of the distribution. The stabilised version of the algorithm is pragmatic and provides reliable inference. We demonstrate our approach using an evidence synthesis for inferring HIV prevalence, and an evidence synthesis of A/H1N1 influenza.
Comparison of two Medication Therapy Management Practice Models on Return on Investment
Creators: name: Berenbrok, Lucas A
name: Ferreri, Stefanie P
name: Gazda, Nicholas P
Publisher: name: SAGE Publications
Year: 2016

description: OBJECTIVE: To compare the return on investment (ROI) of an integrated practice model versus a "hub and spoke" practice model of pharmacist provided medication therapy management (MTM).
METHODS: A cohort retrospective analysis of MTM claims billed in 76 pharmacies in North Carolina in the 2010 hub and spoke practice model and the 2012 "integrated" practice model were analyzed to calculate the ROI.
RESULTS: In 2010, 4089 patients received an MTM resulting in 8757 claims in the hub and spoke model. In 2012, 4896 patients received an MTM resulting in 13 730 claims in the integrated model. In 2010, US$165 897.26 was invested in pharmacist salary and $173 498.00 was received in reimbursement, resulting in an ROI of +US$7600.74 (+4.6%). In 2012, US$280 890.09 was invested in pharmacist salary and US$302 963 was received in reimbursement, resulting in an ROI of +US$22 072.91 or (+7.9%).
CONCLUSION: The integrated model of MTM showed an increase in number of claims submitted and in number of patients receiving MTM services, ultimately resulting in a higher ROI. While a higher ROI was evident in the integrated model, both models resulted in positive ROI (1:12-1:21), highlighting that MTM programs can be cost effective with different strategies of execution.
Cannadicas A and B: two new oligosaccharide esters from the roots of Canna indica L.
Creators: name: Luu The Anh
name: Hieu, Nguyen
name: Trang, Do Thi
name: Tai, Bui Huu
name: Nhiem, Nguyen Xuan
name: Van Kiem, Phan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Plant Biology

description: Two new sucrose derivatives, named as cannadica A (1) and cannadica B (2), and eight known compounds, 6′-O-acetyl-3-O-(E)-p-coumaroylsucrose (3), heterophylloside C (4), 6′-O-vanilloylarbutin (5), isotachioside (6), 2,6-dimethoxy-p-hydroquinone 1-O-β-D-glucopyranoside (7), 3,5-dimethoxy-p-hydroquinone 1-O-β-D-glucopyranoside (8), benzyl glucoside (9), and 3,4-dihydroxybenzaldehyde (10) were isolated from the roots of Canna indica L. by various chromatographic methods. Their structures were established by extensive spectroscopic analysis (UV, IR, HR-ESI-MS and NMR) and by comparison of the spectral data with those reported in the literature. Compounds 1-10 were evaluated their antioxidant activity by peroxyl radical absorbance capacity assay. Compounds 4 and 5 exhibited the most peroxyl radical absorbance capacity. At concentration of 1 µM, their ORACROO* values were 4.86 ± 0.39 and 3.11 ± 0.26, respectively, fold-up to that of trolox as an internal standard.
Spodochlamys marahuaca Jameson and Ratcliffe 2011
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Spodochlamys
Spodochlamys marahuaca

description: § Spodochlamys marahuaca Jameson and Ratcliffe, 2011
Spodochlamys marahuaca Jameson and Ratcliffe 2011: 74 (Venezuela (EO))
Distribution. Venezuela (EO): Jameson and Ratcliffe 2011: 74 (EO).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 119, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 22931.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.10.1968, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Psychiatric nursing intervention in depressed elderly patients
Creators: name: Creson, Pawnee Payne
Publisher: name: University of Utah
Year: 2012
Subjects: Psychiatric nursing
Geriatric psychiatry
Depression, Mental

description: It was postulated that the elderly person would respond favorably by a reduction of depressive symptoms if provided the opportunity for participation in a group situation.  The purpose of the study was to determine the effectiveness of planned short term psychiatric nursing intervention in group work with depressed elderly patients.  Sixteen patients were treated in two groups:  group I designed to interrupt the depression through psychotherapeutic group experiences, and group II designed to provide an effective social group experience through group discussion.  The groups were continued over a period of six weeks, meeting three times weekly.  Comparison of the results of the two methods of intervention was made through testing before, during, and after group experiences.  The Zung Self-rating Depression Scale was given to both groups of patients.  The results, using a t test, showed that there was no significant change in the degree of depression of patients in either group.  Analysis of variance of the data from the opinion needs questionnaire, given to both groups, suggested that there is a need for nursing to explore the special problems of the elderly in nursing homes.  The patients expressed opinions about the nursing care they received in four categories:  interpersonal needs, physical needs, knowledge needs social needs.  The patients in Group I expressed more positive opinions about nursing care than the patients in Group II.  Although the results were not of statistical significance, the trend was toward support of the hypothesis that elderly patients provide with a psychiatric nursing intervention would show an increase in positive opinions expressed about nursing care.  The greatest degree of change occurred in the category concerned with interpersonal needs.  Implications of the study for nursing care of elderly patients in nursing homes were made, along with this population.  Continuation of the group work with elderly patients over a longer period of time was suggested in order to explore the trend indicated in Group I toward positive change in the depressive symptoms.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.11.1968, erstellt von Gisèle Evrard-Kesteloot, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle. Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Fotografische Sonnenaufnahme und zugehörige Zeichnung, unnummeriert, einen Zürcher Lückentag ergänzend.
Fotoabzug und durchgepauste Zeichnung der Aufnahme von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.12.1968, fotografiert von John S. Korintus
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Der Abzug ist auf der Rückseite mit genauen Angaben versehen. Flecken und Fackelflächen sind auf das Pauspapier übertragen. Im Jahresbericht für das vorliegende Jahr ist John S. Korintus nicht erwähnt
Dynamics of Competition in the Hungarian Poultry Industry
Creators: name: Bareith, Tibor
name: Csonka, Arnold
name: Bareith, Tibor
name: Csonka, Arnold
Publisher: name: Unknown
Year: 2022
Subjects: subject: Agricultural and Food Policy
subject: Research and Development/Tech Change/Emerging Technologies
subject: Risk and Uncertainty
subject: profit persistence, poultry, competition, agriculture

description: This study examines the competitive nature of the Hungarian poultry sector between 2006 and 2016. The poultry population has stagnated over the period investigated, however the farm structure has changed significantly and the population of poultry held by individual farms has decreased. In this research, market competition was measured with the persistence of abnormal profits, while profit persistence was estimated using the Arellano-Bond GMM and Blundell-Bond dynamic panel regression. Based on the results, it can be said that the level of profit in the poultry sector is close to the equilibrium profit level. The farm size, technological development as well as the tax advantages of individual farms distort competition leading to higher profits. Taking long-term risk has a negative impact on abnormal profits. The results of the research suggests that the breakthrough points for the poultry sector are technological progress and population growth, as well as a reduction in labor intensity.
Sonnenfleckenzeichnung Nr. 22910.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.09.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen
Mechanistic insight into functional sympatholysis in human skeletal muscle feed arteries
Creators: name: Ives, Stephen James
Publisher: name: University of Utah
Year: 2012
Subjects: Adrenergic
Blood flow
pH
Sympatholysis
Temperature
Vascular
Human skeletal muscle
Feed arteries

description: Through the use of in vitro methods, previous research in animal models has attempted to isolate the effects of local metabolic factors, normally associated with  exercising skeletal muscle, on vascular reactivity and thus blood flow regulation.  Utilizing an in vitro vessel approach and human skeletal muscle feed arteries, the purpose of these studies was to determine if local factors, such as heat and acidosis, could alter vascular reactivity and thus contribute to reduced sympathetically induced vasoconstriction (functional sympatholysis) and exercise hyperemia. Specifically, it was hypothesized that heat and acidosis will suppress vasocontracile function in human  skeletal muscle feed arteries. The first study investigated the effect of temperature on ?1-  adrenergic receptor stimulation using phenylephrine (PE). Cooling to 35 °C or heating to 39 °C both resulted in an attenuated PE-induced vasocontraction, while smooth muscle function, as determined by KCl, remained unchanged. The goal of the second study was  to determine if the potent vasodilator, nitric oxide (NO), could be a factor mediating the heat-induced attenuation in PE-induced contraction observed in the first study. Heating again reduced PE-induced vasocontraction, and was restored with NO blockade. Using molecular approaches, it was determined that heating did not change the density of ?1-receptors, but increased endothelial nitric oxide synthase (eNOS) protein expression. The third study sought to determine the effect of acidosis on vascular reactivity. Increasing  levels of acidosis resulted in graded reductions in ?1- receptor-induced vasocontraction, which was in part due to reduced smooth muscle function as assessed by KCl. Increasing acidosis maintained maximal vasorelaxation and suggested enhanced sensitivity to both the endothelium-dependent agonist acetylcholine (ACh) and the endotheliumindependent NO donor sodium nitroprusside (SNP). Collectively, these results indicate  that local factors normally associated with exercise-induced increases in skeletal muscle metabolism (i.e. heat and acidosis) are, in fact, capable of altering feed artery vascular reactivity in humans, and therefore likely play a role in sympatholysis in vivo.
Sonnenfleckenzeichnung Nr. 22898.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.09.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Quantitative evaluation of the peroxidase-antiperoxidase-diaminobenzidine stain in double stained prostatic tumor slides by dual wavelength technique
Creators: name: Zhou, Ruixia
Publisher: name: University of Utah
Year: 2012
Subjects: Cancer
Data Processing

description: The aim of this study is to develop a method to quantitate the Prostate-Specific Acid Phosphatase (PSAP) in double stained histologic sections of prostate tumor tissue, in which the PSAP is labeled with the peroxidase-antiperoxidase (PAP) complex technique using diaminobenzidine (DAB) as a substrate (brown PAP-DAB stain) while the nuclei are stained with hematoxylin (blue stain). After development of the method, studies of clinical prostate tissue sections of RTOG (radiation therapy of oncology group) protocols will be performed.  In order to make the measurement of the brown PAP-DAB stain independent in the second stain (blue stain), a new color segmentation method, called dual wavelength technique, is developed to separate the brown stain and blue stain components in actual stained slides. Two lOnm bandpass filters, peaked at 450nm and 510nm wavelength, are used in the image acquisition. Using the wavelength dependent mass absorptivity ratios of the two stains estimated in slides stained only brown or blue, the blue stain and the brown stain are completely separated by the dual wavelength technique. The blue stain is located in the nuclei and the brown stain is located in the prostate gland cytoplasm.  Using the mass absorptivity of the brown PAP-DAB stain obtained in a simulating experiment, an estimation of the brown PAP-DAB stain mass is obtained. The reliability, investigated by comparing the measured mass with the true value, is indicated by a correlation coefficient 0.99, and the linear relationship with the slope 1.097 and intercept 0.00022.  A quantitative evaluation of the PAP-DAB stain intensity and extent in clinical prostatic tumor sections is taken on the stain images completely separated by this technique. The PAP-DAB stain intensity is estimated by the average stain mass per stain area (8) and the average stain mass taken up by one cell (I), while the stain extent is measured by the average stain area taken up by one cell (E). In a preliminary study, it has been demonstrated that this evaluation is precise and reproducible. In order to limit the variations resulting from section thickness and stain conditions, the degree of PAP-DAB stain intensity and extent of one slide are evaluated by comparing the features of tumor glands with those of control glands in the same slide.  A batch mode process, for evaluating a large group of slides, is developed using a PC 286 based imaging system and a SUN system. Using this batch mode processing technique, the evaluation of a large group of slides can be repeated without image re-acquisition. The PC based imaging system is connected to a SUN system through ETHERNET. The sequential steps involved in this batch mode process are image acquisition on the PC based imaging system, image transfer through ETHERNET, and image evaluating on SUN workstation.
Sonnenfleckenzeichnung Nr. 22942.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.11.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Modulation of biogenic amine enzymes
Creators: name: Bakhit, Ivan Charles
Publisher: name: University of Utah
Year: 2012
Subjects: Psychotropic drugs
Neurotransmitters
Enzyme inhibitors
Amines in the body

description: Acute administration of haloperidol to rats causes a marked decrease in the Km of neostriatal tyrosine hydroxylase for the pteridine cofactor, 6MPH(,4), with no change in Vmax. This effect is dependent on the pH of the assay mixture. It occurs at pH 6.5 but not at pH 6.0, the pH optimum for TH. With phosphorylating conditions at pH 6.5, the haloperidol-induced activation is no longer observed, and the kinetics of TH are the same as those from control rats. At pH values of 6.0, 6.3 and 6.5, a significant decrease in Vmax occurs, with increasing pH, while no significant change in Km for the cofactor is observed for TH from control rats. However, when phosphorylating conditions are employed, a marked increase in Km for the cofactor is observed while only a slight decrease in Vmax is seen, with increasing pH, for the control enzyme at the three pH values tested. The kinetic characteristics of neostriatal tyrosine hydroxylase (TH) activity were then determined after rats were given large, repeated doses of methamphetamine. The Vmax of the enzyme was markedly decreased after methamphetamine, but no change in the Km for pteridine cofactors nor for the substrate, tyrosine, was detected. The decrease in Vmax with methamphetaminee was independent of the phosphorylated state of the enzyme. The effect of propranolol in blocking the methamphetamine-induced depression of tryptophan hydroxylase was then investigated. Acute administration of methamphetamine produced a marked decrease in tryptophan hydroxylase activity in all serotonergic nerve terminal regions of rat brain examined. This decrease was antagonized in a regionally selective manner by propranolol. Almost complete blockade occurred in regions that are commonly implicated in schizophrenia, mesolimbic areas, neostriatum, and hypothalamus; whereas in other regions examined, only partial or no blockade occurred. In contrast, haloperidol did not produce a similar antagonism. The results are discussed in the context of the efficacy of large doses of propranolol in some schizophrenic patients.
Spodochlamys neblina Jameson and Ratcliffe 2011
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Spodochlamys
Spodochlamys neblina

description: § Spodochlamys neblina Jameson and Ratcliffe, 2011
Spodochlamys neblina Jameson and Ratcliffe 2011: 83 (Venezuela (EO))
Distribution. Venezuela (EO): Jameson and Ratcliffe 2011: 83 (EO).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 119, DOI: 10.5281/zenodo.3678492
Cosmid vector design for large scale sequencing: the Pyrococcus furiosus genome
Creators: name: Yeh, Raymond K.
Publisher: name: University of Utah
Year: 2012
Subjects: Microbial
Pyrococcus furiosus

description: Genomic sequencing can be thought of as a process of disassembling a genome into smaller pieces and subsequent reassembly back into the completed genome. This process involves the representation of the genome in libraries of DNA pieces consisting of fractions of the genome ranging in size from 100s of kilobases to hundreds of bases. In order to facilitate the process of library construction and fractionation of genomes a new cosmid vector was designed. The new cosmid vector features an inducible copy number control. Additional features that facilitate production sequencing were also included. The new vector was used in construction of a genomic library of the archea Pyrococcus furious. This library has an average insert size of 33 kb and has a genomic equivalent of 7X. This library, along with a plasmid library, was used to sequence the entire 1,908,253 bases of the P. furiosus genome. During the sequencing it was observed that stability of the cosmids and subsequent recovery of DNA were inversely proportional to the size of the insert size. Smaller inserts were more stable and had higher recovery yields than larger inserts. Further study determined that large inserts decreased the copy number of the cosmid and also inhibited the ability to induce to higher copy number. Various potential explanations were investigated.
Using Simpson’s diversity index to examine multidimensional models of diversity in health professions education
Creators: name: White, Carla Y.
name: McLaughlin, Gerald W.
name: McLaughlin, Jacqueline E.
name: McLaughlin, Josetta S.
Publisher: name: International Journal of Medical Education
Year: 2016

description: OBJECTIVE: This study explored new models of diversity for health professions education that incorporate multiple attributes and examined differences in diversity based on urbanicity, geographic region, and institutional structure.
METHODS: Simpson's Diversity Index was used to develop race, gender, and interprofessional diversity indices for health professions schools in the United States (N = 318). Sullivan's extension was used to develop a composite diversity index that incorporated multiple individual attributes for each school. Pearson's r was used to investigate correlations between continuous variables. ANOVA and independent t-tests were used to compare groups based on urbanicity, geographic region, and Basic Carnegie Classification.
RESULTS: Mean (SD) for race, gender, and interprofessional diversity indices were 0.36(0.17), 0.45(0.07), and 0.22(0.27) respectively. All correlations between the three indices were weak. The composite diversity index for this sample was 0.34(0.13). Significant differences in diversity were found between institutions based on urbanicity, Basic Carnegie Classification, and geographic region.
CONCLUSIONS: Multidimensional models provide support for expanding measures of diversity to include multiple characteristics and attributes. The approach demonstrated in this study enables institutions to complement and extend traditional measures of diversity as a means of providing evidence for decision-making and progress towards institutional initiatives.
Sonnenfleckenzeichnung Nr. 22951.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.11.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 04.09.1968, erstellt vermutlich von Sebestova am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Fotografische Sonnenaufnahme und zugehörige Zeichnung, unnummeriert.
Fotoabzug und durchgepauste Zeichnung der Aufnahme von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.10.1968, fotografiert von John S. Korintus
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Der Abzug ist auf der Rückseite mit genauen Angaben versehen. Flecken und Fackelflächen sind auf das Pauspapier übertragen. Im Jahresbericht für das vorliegende Jahr ist John S. Korintus nicht erwähnt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.12.1968, erstellt als zweite Tagesaufnahme um 9 h 40 von Gisèle Evrard-Kesteloot, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Efficient embryoid-based method to improve generation of optic vesicles from human induced pluripotent stem cells.
Creators: name: Eintracht, Jonathan
name: Harding, Philippa
name: Cunha, Dulce Lima
name: Moosajee, Mariya
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Model organisms
subject: Gene Expression
subject: Genetics & Genomics
subject: Developmental Biology
subject: Human Biology & Physiology
subject: Stem Cells

description: Animal models have provided many insights into ocular development and disease, but they remain suboptimal for understanding human oculogenesis. Eye development requires spatiotemporal gene expression patterns and disease phenotypes can differ significantly between humans and animal models, with patient-associated mutations causing embryonic lethality reported in some animal models. The emergence of human induced pluripotent stem cell (hiPSC) technology has provided a new resource for dissecting the complex nature of early eye morphogenesis through the generation of three-dimensional (3D) cellular models. By using patient-specific hiPSCs to generate in vitro optic vesicle-like models, we can enhance the understanding of early developmental eye disorders and provide a pre-clinical platform for disease modelling and therapeutics testing. A major challenge of in vitro optic vesicle generation is the low efficiency of differentiation in 3D cultures. To address this, we adapted a previously published protocol of retinal organoid differentiation to improve embryoid body formation using a microwell plate. Established morphology, upregulated transcript levels of known early eye-field transcription factors and protein expression of standard retinal progenitor markers confirmed the optic vesicle/presumptive optic cup identity of in vitro models between day 20 and 50 of culture. This adapted protocol is relevant to researchers seeking a physiologically relevant model of early human ocular development and disease with a view to replacing animal models.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 31.10.1968, erstellt am Sonnenobservatorium Kanzelhöhe, Kärnten
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage im Sonnenobservatorium Kanzelhöhe in Sattendorf, Österreich. Instrument: Heliostat mit Refraktor Eigenbau (Öffnung 110mm, f = 1650mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.09.1968, erstellt am Sonnenobservatorium der Universität Teheran
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Zeichnung von Sonnenflecken (Bleistift und Farbstift), erstellt als Projektionsbildzeichnung in Teheran.
Unter Umständen im Zusammenhang mit Beobachtungen des Air Weather Service der U.S. Air Force im Auftrag des NASA Controll Centers in Houston erstellt. Instrument: unbekannt.
Instrument unbekannt
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.11.1968, erstellt von Dendis am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 31.10.1968, erstellt von Dendis am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 31.10.1968, erstellt am Sonnenobservatorium der Universität Teheran
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Zeichnung von Sonnenflecken (Bleistift und Farbstift), erstellt als Projektionsbildzeichnung in Teheran.
Unter Umständen im Zusammenhang mit Beobachtungen des Air Weather Service der U.S. Air Force im Auftrag des NASA Controll Centers in Houston erstellt. Instrument: unbekannt.
Instrument unbekannt
Hybrid approaches to magnetic resonance thermometry using the proton resonance frequency shift and the spin-lattice relaxation time T1
Creators: name: Diakite, Mahamadou
Publisher: name: University of Utah
Year: 2014
Subjects: Proton resonance frequency shift
Pulse sequence
Spin-Lattice relaxation T1
Temperature
Tissue damage

description: Minimally invasive thermal therapy under Magnetic Resonance Imaging (MRI) guidance is becoming popular with several applications in the process of getting FDA approval. The ability to determine in near real-time the temperature map of a tumor and its surrounding tissue makes MR thermometry very attractive and well suited for thermal treatment. The proton resonance frequency shift (PRF) is currently the gold standard method for temperature monitoring using MRI. However, its incapacity to measure temperature in fatty tissue limits the scope of its applicability. The spin lattice relaxation time T1, on the other hand, has shown good temperature sensitivity and works well in all types of tissues. In this dissertation, we have addressed a number of challenges currently affecting MRI thermometry. A non-CPMG Turbo Spin Echo (TSE) sequence has been implemented to monitor the temperature rise due to the high RF power deposition inherent to this sequence at high field (3T and higher). This new implementation allows TSE sequences to be used safely without altering their high contrast properties which make them appealing in clinical settings. Tissue damage assessment during thermal therapy is critical for the safety of the patient. We have developed a new hybrid PRF-T1 sequence that has the capability to provide simultaneously in near real-time the temperature map and T1 information, which is a good indication of the state of the tissue. The simplicity and the real-time capability of the newly developed sequence make it an ideal tool for tissue damage assessment. Temperature monitoring during thermal therapy in organs with large fat content have been hindered by the lack of an MRI thermometry method that can provide simultaneous temperature in fat and aqueous tissue. A new sequence and acquisition scheme have been developed to address this issue. In sum, this dissertation proposed several pulse sequence implementation techniques and an acquisition scheme to overcome some of the limitations of MR thermometry.
Sonnenfleckenzeichnung Nr. 22903.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.09.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Mathematical models of epstein-barr virus infection and associated diseases
Creators: name: Huynh, Giao T.
Publisher: name: University of Utah
Year: 2012
Subjects: Epstein-Barr virus
Infectious mononucleosis
Mathematical models
Viral dynamics
Viral entry
Virus-induced cancer

description: Epstein-Barr virus (EBV) infects more than 90% of human population worldwide and has the ability to persist for the lifetime of the infected person. Although EBV infection is most often asymptomatic, the virus causes infectious mononucleosis (IM) in teenagers and young adults. Within a host, EBV can alternate infection between B cells and epithelial cells. The presence of EBV DNA inside these infected cells has been associated with different types of cancers. Many aspects of EBV infection  within a host including the switching infections between cell types, the effects of this switching, the factors involve in regulation of the persistent infection, and what  parts of the regulation can go wrong that induce different types of disease, are not well understood. The aim of our work is studying these aspects using the tools of  mathematical models. We first explore the role of EBV glycoprotein gp42 in the virus entry into target cells. Our models support the role of cooperation of multiple viral  glycoproteins in virus entry and suggest that the intracellular interactions of gp42 with HLA class II in B cells may disrupt gp42 function. We then study the dynamics of EBV infection within a host and show that EBV switching host cell tropism shapes the persistence, evolution, and coexistence of the virus infection. Our model of the within host dynamics suggests that the age dependence of IM can be explained by the host antibodies that enhance infections of epithelial cells and the cross-reactive responses of aggressive but functionally ineffective T cells previously created by other  infections. We also investigate the association of EBV infection with the development of nasopharyngeal carcinoma (NPC), a cancer of epithelial cells in the pharynx. Our model predicts a threshold of the number of effector T cells below which a bifurcation leads to a jump from a low to high level of latently infected epithelial cells that can greatly elevate the risk of NPC development. Our model also produces the patterns of  age-incidence curves that have been observed in low risk and high risk populations.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.12.1968, erstellt am Sonnenobservatorium Kanzelhöhe, Kärnten
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage im Sonnenobservatorium Kanzelhöhe in Sattendorf, Österreich. Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Instrument: Heliostat mit Refraktor Eigenbau (Öffnung 110mm, f = 1650mm, projiziertes Sonnenbild D = 25cm)
Racial Differences in the Association between Parity and Incident Stroke: Results from the Reasons for Geographic and Racial Differences in Stroke Study
Creators: name: Aggarwal, Shivani
name: Vladutiu, Catherine J.
name: Mosher, Aleena
name: Kleindorfer, Dawn
name: Meyer, Michelle L.
name: Howard, Virginia J.
name: Stuebe, Alison M.
name: Malek, Angela M.
Publisher: name: Elsevier
Year: 2016

description: BACKGROUND: Circulatory and vascular changes across consecutive pregnancies may increase the risk of later-life cerebrovascular health outcomes.
METHODS: The association between parity and incident stroke was assessed among 7674 white and 6280 black women, aged 45 years and older, and enrolled in the REasons for Geographic and Racial Differences in Stroke Study from 2003 to 2007. Parity was assessed at baseline, and incident stroke was ascertained from physician-adjudicated medical records through September 2014. Cox proportional hazards models were used to estimate hazard ratios (HR) for the association between parity and stroke, adjusting for baseline measures.
RESULTS: At baseline, 12.7% of white women and 16.2% of black women reported 1 live birth, while 8.2% and 19.0%, respectively, reported 5 or more live births. Mean follow-up time was 7.5 years (standard deviation = 2.8); there were 447 incident strokes. A significant interaction between race and parity was detected (P = .05). Among white women, those with 5 or more live births had a higher stroke risk than those with 1 live birth (HR = 1.57; 95% confidence interval [CI] .93-2.65). However, the association was eliminated after adjustment for baseline characteristics (HR = 1.00, 95% CI .59-1.71). For black women, those with 5 or more live births had the highest stroke risk compared with those with 1 live birth (HR = 1.91, 95% CI 1.25-2.93), but the association was attenuated and no longer statistically significant after adjustment for confounders (HR = 1.40, 95% CI .89-2.18).
CONCLUSIONS: In adjusted models, no statistically significant associations were observed between parity and stroke risk in a diverse cohort of U.S. women. Further studies are needed to elucidate the role of lifestyle and psychosocial factors in the race-specific associations that were observed.
Sonnenfleckenzeichnung Nr. 22894.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.09.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Two new benzophenone glycosides from the aerial parts of Hypericum przewalskii
Creators: name: Xie, Jin-Yan
name: Jin, Qinghao
name: Gao, Jin-Ming
name: Zong, Shi-Chun
name: Yan, Xi-Tao
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: Plants of the genus Hypericum contain various types of secondary metabolites that exhibited extensive biological activities. In the ongoing efforts to discover natural neuroinflammatory inhibitors with the potential to develop into therapeutic agents for neurodegenerative diseases, two new benzophenone glycosides, hyperewalones A and B (1 and 2), along with eight known compounds (3–10), were isolated from the aerial parts of Hypericum przewalskii. Their structures were elucidated by comprehensive analysis of IR, HRESIMS, 1D and 2D NMR spectra, and chemical derivatization. The anti-neuroinflammatory activity of compounds 1–10 was evaluated by determining their ability to inhibit the production of nitric oxide (NO) in lipopolysaccharide (LPS)-activated BV-2 microglial cells. Compounds 2, 4, 6–8 exhibited significant anti-neuroinflammatory activity with IC50 values of 0.61–4.90 μM. These findings suggest that the benzophenone, ionone, and flavonoid glycosides isolated from H. przewalskii are promising anti-neuroinflammatory compounds worthy of further investigations.
Anomalina Streubel 1839
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Chromista
Foraminifera
Globothalamea
Rotaliida
Anomalinidae
Anomalina

description: ANOMALINA Streubel, 1839
Note. According to Ramírez-Ponce and Morón (2009), the American species of Anomala Samouelle, 1819 (p. 191) as well as several species of American Callistethus Blanchard, 1851 (p. 198) belong in the genus Paranomala Casey, 1915 (p. 12). Because Ramírez-Ponce and Morón (2009) treat only two of the many dozens of South American species, we have decided not to follow the proposed nomenclatural changes until the South American fauna is better studied.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 119, DOI: 10.5281/zenodo.3678492