cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Revisiting the D-RECT tool: Validation of an instrument measuring residents’ learning climate perceptions
Creators: name: Onyebuchi A. Arah
name: Silkens, Milou E.W.M.
name: Smirnova, Alina
name: Stalmeijer, Renee E.
name: Scherpbier, Albert J.J.A.
name: Vleuten, Cees P.M. Van Der
name: Lombarts, Kiki M.J.M.H.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Earth and Environmental Sciences

description: Introduction: Credible evaluation of the learning climate requires valid and reliable instruments in order to inform quality improvement activities. Since its initial validation the Dutch Residency Educational Climate Test (D-RECT) has been increasingly used to evaluate the learning climate, yet it has not been tested in its final form and on the actual level of use – the department.Aim: Our aim was to re-investigate the internal validity and reliability of the D-RECT at the resident and department levels.Methods: D-RECT evaluations collected during 2012–2013 were included. Internal validity was assessed using exploratory and confirmatory factor analyses. Reliability was assessed using generalizability theory.Results: In total, 2306 evaluations and 291 departments were included. Exploratory factor analysis showed a 9-factor structure containing 35 items: teamwork, role of specialty tutor, coaching and assessment, formal education, resident peer collaboration, work is adapted to residents’ competence, patient sign-out, educational atmosphere, and accessibility of supervisors. Confirmatory factor analysis indicated acceptable to good fit. Three resident evaluations were needed to assess the overall learning climate reliably and eight residents to assess the subscales.Conclusion: This study reaffirms the reliability and internal validity of the D-RECT in measuring residency training learning climate. Ongoing evaluation of the instrument remains important.
The effects of consuming alcohol mixed with energy drinks (AMED) versus consuming alcohol only on overall alcohol consumption and alcohol-related negative consequences
Creators: name: de Haan, Lydia
name: de Haan, Hein A.
name: van der Palen, Job
name: Olivier, Berend
name: Verster, Joris
Publisher: name: Swinburne
Year: 2024

description: Background: The aim of this study was to examine differences in alcohol consumption and its consequences when consumed alone and when mixed with energy drinks.
Methods: A survey was conducted among Dutch students at Utrecht University and the College of Utrecht. We collected data on alcohol consumption and alcohol-related consequences of alcohol consumed alone and/or alcohol mixed with energy drinks (AMED). The data were analyzed using a retrospective within-subject design, comparing occasions when subjects consumed AMED with those when they consumed alcohol only in the past 30 days.
Results: A representative sample of 6002 students completed the survey, including 1239 who consumed AMED. Compared with consuming alcohol only, when consuming AMED, students consumed significantly fewer alcoholic drinks on an average drinking day (6.0 versus 5.4, respectively), and reported significantly fewer drinking days in the previous month (9.2 versus 1.4), significantly fewer days being drunk (1.9 versus 0.5), and significantly fewer occasions of consuming more than four (female)/five (male) alcoholic drinks (4.7 versus 0.9). The maximum number of mixed alcoholic drinks (4.5) in the previous month was significantly lower when compared with occasions when they consumed alcohol only (10.7). Accordingly, the mean duration of a drinking session was significantly shorter when mixing alcoholic drinks (4.0 versus 6.0 hours). Finally, when consuming AMED, significantly fewer alcohol-related consequences were reported (2.6) for the previous year, including driving a car while intoxicated, taking foolish risks, or being injured or hurt, as compared with alcohol-related consequences when consuming alcohol only (4.9).
Conclusion: Mixing alcohol with energy drinks decreases overall alcohol consumption, and decreases the likelihood of experiencing negative alcohol-related consequences.
5 Recommendations to Help Your Organization Manage Technical Debt.
Creators: name: Ozkaya, Ipek
Publisher: name: Carnegie Mellon University
Year: 2024
Subjects: Software Engineering

description: The fiscal year 2022 National Defense Authorization Act (NDAA) Section 835, “Independent Study on Technical Debt in Software-Intensive Systems,” required the Secretary of Defense to engage a federally funded research and development center (FFRDC) “to study technical debt in software-intensive systems.” To satisfy this requirement and lead this work, the Department of Defense (DoD) selected the Carnegie Mellon University (CMU) Software Engineering Institute (SEI), which is a recognized leader in the practice of managing technical debt. According to NDAA Section 835, the purpose of the study was to provide, among other things, analyses and recommendations on quantitative measures for assessing technical debt, current and best practices for measuring and managing technical debt and its associated costs, and practices for reducing technical debt. Our team spent more than a year conducting the independent study. The report we produced describes the conduct of the study, summarizes the technical trends observed, and presents the resulting recommendations. In this SEI Blog post, we summarize several recommendations that apply to the DoD and other development organizations seeking to analyze, manage, and reduce technical debt. You can find a complete discussion of the study methodology, findings, and recommendations in the SEI’s Report to the Congressional Defense Committees on National Defense Authorization Act (NDAA) for Fiscal Year 2022 Section 835 Independent Study on Technical Debt in Software-Intensive Systems.
Building a relationship between robot characteristics and teleoperation user interfaces
Creators: name: Mortimer, Michael
name: Horan, Ben
name: Seyedmahmoudian, Mehdi
Publisher: name: Swinburne
Year: 2024

description: The Robot Operating System (ROS) provides roboticists with a standardized and distributed framework for real-time communication between robotic systems using a microkernel environment. This paper looks at how ROS metadata, Unified Robot Description Format (URDF), Semantic Robot Description Format (SRDF), and its message description language, can be used to identify key robot characteristics to inform User Interface (UI) design for the teleoperation of heterogeneous robot teams. Logical relationships between UI components and robot characteristics are defined by a set of relationship rules created using relevant and available information including developer expertise and ROS metadata. This provides a significant opportunity to move towards a rule-driven approach for generating the designs of teleoperation UIs; in particular the reduction of the number of different UI configurations required to teleoperate each individual robot within a heterogeneous robot team. This approach is based on using an underlying rule set identifying robots that can be teleoperated using the same UI configuration due to having the same or similar robot characteristics. Aside from reducing the number of different UI configurations an operator needs to be familiar with, this approach also supports consistency in UI configurations when a teleoperator is periodically switching between different robots. To achieve this aim, a Matlab toolbox is developed providing users with the ability to define rules specifying the relationship between robot characteristics and UI components. Once rules are defined, selections that best describe the characteristics of the robot type within a particular heterogeneous robot team can be made. A main advantage of this approach is that rather than specifying discrete robots comprising the team, the user can specify characteristics of the team more generally allowing the system to deal with slight variations that may occur in the future. In fact, by using the defined relationship rules and characteristic selections, the toolbox can automatically identify a reduced set of UI configurations required to control possible robot team configurations, as opposed to the traditional ad-hoc approach to teleoperation UI design. In the results section, three test cases are presented to demonstrate how the selection of different robot characteristics builds a number of robot characteristic combinations, and how the relationship rules are used to determine a reduced set of required UI configurations needed to control each individual robot in the robot team.
title: 5 Recommendations to Help Your Organization Manage Technical Debt
Creators: name: Ozkaya, Ipek
name: O'Hearn, Brigid
Publisher: name: Software Engineering Institute, Carnegie Mellon University
Year: 2024

description: This SEI Blog post summarizes recommendations arising from an SEI study that apply to the Department of Defense and other development organizations seeking to analyze, manage, and reduce technical debt.
Impact of disease, cognitive and behavioural factors on caregiver outcome in amyotrophic lateral sclerosis
Creators: name: Tamlyn J. Watermeyer
name: Brown, Richard G.
name: Sidle, Katie C. L.
name: Oliver, David J.
name: Allen, Christopher
name: Karlsson, Joanna
name: Ellis, Cathy
name: Shaw, Christopher E.
name: Al-Chalabi, Ammar
name: Goldstein, Laura H.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Neuroscience
subject: Medicine

description: Up to 50% of patients with amyotrophic lateral sclerosis (ALS) show mild to moderate cognitive-behavioural change alongside their progressive functional impairment. This study examines the relative impact of patients’ disease symptoms, behavioural change and current executive function and social cognition abilities on psychosocial outcomes in spouse caregivers of people with ALS. Thirty-five spouse caregivers rated their own levels of depression and anxiety, subjective burden and marital satisfaction. Caregivers also rated their partner’s everyday behaviour. The patients were assessed for disease severity and cognitive function, with composite scores derived for executive function and social cognition. Regression analyses revealed that caregiver burden was predicted by the severity of patients’ limb involvement and behavioural problems. Depression was predicted by patients’ limb involvement, while behavioural problems and patient age predicted caregiver anxiety. Current marital satisfaction was predicted by patient behavioural problems beyond the level of pre-illness marital satisfaction. In conclusion, the study highlights the potential impact of ALS patients’ functional impairment and behavioural change on ALS caregivers’ psychosocial functioning. Clinical communication with ALS families should emphasise both physical and psychological challenges presented by the disease.
Scenario-Based Validation of Requirements for Context-Aware Adaptive Services
Creators: name: Hussein, Mahmoud
name: Han, Jun
name: Yu, Jian
name: Colman, Alan
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 460308
subject: Pattern recognition
classificationCode: 460502
subject: Data mining and knowledge discovery
classificationCode: 460612
subject: Service oriented computing
classificationCode: 461104
subject: Neural networks
classificationCode: 461201
subject: Automated software engineering
classificationCode: 461202
subject: Empirical software engineering

description: Context-awareness and adaptability are highly desirable features for services that are operating in dynamic environments. Recently, a number of approaches have been introduced to support the development of such services. But, validating the varying requirements of these services is still a major challenge. In this paper, we introduce a novel scenario-based approach to address this challenge. First, our approach captures a service's requirements as two sets of scenarios: functional and adaptation. The functional scenarios represent the service's core functionality, while the adaptation scenarios capture the service's runtime adaptation in response to context changes. The service properties that need to hold at runtime are also represented graphically in a form similar to the scenarios. Second, a technique is introduced to enumerate and generate the specifications of a service's variants from its scenarios. The generated variants are then validated against the service properties to ensure their validity. This technique also checks the consistency of the service's adaptation requirements (scenarios). Case studies have shown that with our approach, a small number of service scenarios specified by the software engineer is able to cover a large number of service variants, which are generated and validated automatically.
Investigation of binding mechanism of novel 8-substituted coumarin derivatives with human serum albumin and α-1-glycoprotein
Creators: name: Yeggoni, Daniel Pushpa Raju
name: Manidhar, Darla Mark
name: Cirandur Suresh Reddy
name: Rajagopal Subramanyam
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Coumarin molecules have biological activities possessing lipid-controlling activity, anti-hepatitis C activity, anti-diabetic, anti-Parkinson activity, and anti-cancer activity. Here, we have presented an inclusive study on the interaction of 8-substituted-7-hydroxy coumarin derivatives (Umb-1/Umb-2) with α-1-glycoprotein (AGP) and human serum albumin (HSA) which are the major carrier proteins in the human blood plasma. Binding constants obtained from fluorescence emission data were found to be KUmb-1=3.1 ± .01 × 104 M−1, KUmb-2 = 7 ± .01 × 104 M−1, which corresponds to −6.1 and −6.5 kcal/mol of free energy for Umb-1 and Umb-2, respectively, suggesting that these derivatives bind strongly to HSA. Also these molecules bind to AGP with binding constants of KUmb-1-AGP=3.1 ± .01 × 103 M−1 and KUmb-2-AGP = 4.6 ± .01 × 103 M−1. Further, the distance, r between the donor (HSA) and acceptor (Umb-1/Umb-2) was calculated based on the Forster’s theory of non-radiation energy transfer and the values were observed to be 1.14 and 1.29 nm in Umb-1–HSA and Umb-2–HSA system, respectively. The protein secondary structure of HSA was partially unfolded upon binding of Umb-1 and Umb-2. Furthermore, site displacement experiments with lidocaine, phenylbutazone (IIA), and ibuprofen (IIIA) proves that Umb derivatives significantly bind to subdomain IIIA of HSA which is further supported by docking studies. Furthermore, Umb-1 binds to LYS402 with one hydrogen bond distance of 2.8 Å and Umb-2 binds to GLU354 with one hydrogen bond at a distance of 2.0 Å. Moreover, these molecules are stabilized by hydrophobic interactions and hydrogen bond between the hydroxyl groups of carbon-3 of coumarin derivatives.
Factors promoting innovation and efficiency in the construction industry: A comparative study of New zealand and Australia
Creators: name: Chancellor, Will
name: Abbott, Malcolm
name: Carson, Chris
Publisher: name: Swinburne
Year: 2024

description: There have been numerous concerns about the lack of productivity improvement in the New Zealand construction industry. The aim of this paper, therefore, is to determine the main drivers of productivity in the industry. The research used is a two-staged data envelopment analysis approach to achieve the aim. In terms of improvements to the productivity of construction in New Zealand, the study found that although there is a potential for gains through the greater use of research and development, apprentice training and degree education, as well as the consolidation of some building companies, there will be some limits to the gains that might be made. One main implication of the findings of the study, therefore, is that a renewed focus on education and skills training should be a priority of companies and policy makers in New Zealand.
The effects of lateral halogen substituents on the low-temperature cybotactic nematic phase in oxadiazole based bent-core liquid crystals
Creators: name: Nguyen, Jason
name: Wonderly, William
name: Tauscher, Tatum
name: Harkins, Robin
name: Vita, Francesco
name: Portale, Giuseppe
name: Francescangeli, Oriano
name: Samulski, Edward T.
name: Scharrer, Eric
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry

description: We have previously demonstrated that the incorporation of lateral methyl groups on oxadiazole-based liquid crystals leads to relatively low-temperature cybotactic nematic phases which, in some cases, supercool to room temperature. We report here the synthesis and phase behaviour of related compounds that possess lateral halogen groups and in some cases, lateral methyl groups as well. Derivatives with three lateral substituents (one halogen and two methyl groups) in a specific pattern supercool in the nematic phase to room temperature. As was the case with the previously reported trimethylated derivatives, the low-temperature nematic phase is glassy in nature. Two of the new trisubstituted derivatives (with bromo and chloro groups) remain in the nematic phase upon subsequent heating until transitioning to the isotropic phase indicating that the low-temperature nematic phase may be more stable than that shown by the trimethylated analogue. Preliminary X-ray diffraction analysis confirms the presence of a tilted cybotactic nematic phase. In addition, the splitting observed in the wide-angle scattering feature is indicative of enhanced local biaxial packing.
A Study of Architectural Information Foraging in Software Architecture Documents
Creators: name: Su, Moon Ting
name: Tempero, Ewan
name: Hosking, John
name: Grundy, John
Publisher: name: Swinburne
Year: 2024

description: When using Software Architecture documents (ADs), users typically 'forage' for information. However, it is little understood how they do this foraging or how to structure architecture documentation to assist them. We conducted a survey of two different groups of foragers, industry practitioner and academic AD users, to investigate issues - types of forages, foraging sequences and styles - related to task-based architectural information foraging in software architecture documents. Our results show that there were different pre-conceived ideas of what to forage for prior to the search, but during foraging there was commonly foraged information. The different groups of foragers place different emphasis on information related to quality requirements, purpose of the system, use cases, physical view and process view. Foraging sequences starting with certain information were suggested to better support understanding of the described SA. These sequences typically followed the written order of the information as dictated by the AD producers. This reinforces the critical responsibility of AD producers to structure the architectural information for understanding. Diagrams, views and design decisions were most frequently cited as supporting understanding of the SA. The main hindrance was too much text and a lack of diagrams.
Sabanejewia aurata
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Cypriniformes
Cobitidae
Sabanejewia
Sabanejewia aurata

description: 28. Sabanejewia aurata (De Filippi, 1863)
Common name. Golden spined loach
Taxonomy. Original description: Cobitis aurata De Filippi, 1863: 391 [Stream near Sartschem (apparently Sarcham-e Sofla, 39°07'N, 47°54'E), Iran; lectotype: MZUT 674; lectotype selected by Tortonese (1961: 188)].
Revisions. Berg (1949: 894) as Cobitis aurata, Vasil'eva et al. (2022: 12).
Illustrations. Berg (1949: 894-895, figs. 644-645) as Cobitis aurata and Sayyadzadeh et al. (2018a: 279-284, figs. 2-7).
Distribution in Iran. —Distribution in River Basin: Caspian Sea.—Distribution in Ecoregions: 434-Kura-South Caspian Drainages.
Status in Iran. [Native].—Roftgar mahi-e talaee.—Listed in previous checklists from Iran by Esmaeili et al. (2017 a, 2018); Jouladeh-Roudbar et al. (2020) and Eagderi et al. (2022).—Iran material: ZM-CBSU.
Conservation. —IUCN: LC.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on page 16, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097
Chromosomal sex determines gonadal sex, but it is not enough for male phenotype: Novel mutation in androgen receptor gene
Creators: name: H. Alptekin
name: S. Barış
name: M. Yıldız
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Computational Biology
subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Chemistry
subject: Evolutionary Biology
subject: Pharmacology
subject: Physiology
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Medicine
subject: Biochemistry

description: Chromosomal sex determines gonadal sex, but it is not enough for male phenotype: Novel mutation in androgen receptor gene
Enabling Runtime Evolution of Context-Aware Adaptive Services
Creators: name: Hussein, Mahmoud
name: Han, Jun
name: Yu, Jian
name: Colman, Alan
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 460308
subject: Pattern recognition
classificationCode: 460502
subject: Data mining and knowledge discovery
classificationCode: 460612
subject: Service oriented computing
classificationCode: 461104
subject: Neural networks
classificationCode: 461201
subject: Automated software engineering
classificationCode: 461202
subject: Empirical software engineering

description: There is an increasing demand for context-aware adaptive services that can evolve at runtime in response to unanticipated changes in their environments or functionalities. Enabling the runtime evolution of such context-aware adaptive services is still a major challenge. In this paper, we introduce a novel approach to tackle this challenge. At the development time, our approach explicitly models a context-aware adaptive service from three aspects: functionality, context, and adaptive behaviour. As such, these aspects and their relationships can be clearly captured and easily manipulated. The approach also generates the executable artifacts of the composite service from their models. These artifacts are engineered with the ability to be changed at runtime (i.e. evolvable artifacts). To cope with unanticipated changes, we adopt the models@runtime concept for keeping the service model alive at runtime. This model is then manipulated by the software engineer to take into account such changes. To apply the model changes to the running service's composition, differences between the running service model and its evolved model are computed. Then, adaptation actions corresponding to the differences are generated and applied to the service's evolvable artifacts. To demonstrate the approach applicability, we have used it to develop and evolve two case studies: travel guide and electronic exam services.
A spectroscopic search for high-mass X-ray binaries in M31
Creators: name: Williams, B. F.
name: Hatzidimitriou, D.
name: Green, J.
name: Vasilopoulos, G.
name: Covarrubias, R.
name: Pietsch, W. N.
name: Stiele, H.
name: Haberl, F.
name: Bonfini, Paolo
Publisher: name: Swinburne
Year: 2024

description: We present new optical spectroscopy of 20 candidate counterparts of 17 X-ray sources in the direction of the M31 disc. By comparing the X-ray catalogue from the XMM-Newton survey of M31 with star catalogues from the Local Group Galaxy Survey, we chose counterpart candidates based on optical colour and X-ray hardness. We have discovered 17 counterpart candidates with spectra containing stellar features. Eight of these are early-type stars of O or B type in M31, with hard X-ray spectra, making them good high-mass X-ray binary (HMXB) candidates. Three of these eight exhibit emission lines, which we consider to be the strongest HMXB candidates. In addition, our spectra reveal two likely Galactic cataclysmic variables, one foreground M star, two probable low-mass X-ray binaries related to M31 globular clusters, one emission-line region with an embedded Wolf-Rayet star and one newly discovered supernova remnant. Finally, two of the sources have stellar spectra with no features indicative of association with an X-ray source.
Sabanejewia caspia
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Cypriniformes
Cobitidae
Sabanejewia
Sabanejewia caspia

description: 29. Sabanejewia caspia (Eichwald, 1838)
Common name. Caspian spined loach
Taxonomy. Original description: Cobitis caspia Eichwald, 1838: 133 [Caspian Sea at Lenkoran, Azerbaidjan; No types known].
Revisions. See Sayyadzadeh et al. (2018a).
Illustrations. Sayyadzadeh et al. (2018a: 284-289, figs. 9-14).
Distribution in Iran. —Distribution in River Basin: Caspian Sea.—Distribution in Ecoregions: 434-Kura-South Caspian Drainages.
Status in Iran. [Native].—Roftgar mahi-e khazar.—Listed in previous checklists from Iran by Esmaeili et al. (2017 a, 2018); Jouladeh-Roudbar et al. (2020) and Eagderi et al. (2022); recorded by Sayyadzadeh et al. (2018a).— Iran material: ZM-CBSU.
Conservation. —IUCN: NE.
Remarks. For a long time, the Iranian spined loaches of the genus Sabanejewia have been classified into three species, S. aurata, S. caspia, and S. caucasica (Esmaeili et al. 2010, 2014, 2017, 2018; Jouladeh-Roudbar et al. 2015) but presence of S. caucasica (Sayyadzadeh et al. 2018a: 288, fig. 16) in Iran was under question. It is morphologically similar to S. caspia than to S. aurata and is distinguished from S. caspia by having marbled pigmentation along flank not forming a streak (vs. a narrow continuous dark brown streak along flank in S. caspia); dark blotches on dorsum often fused (vs. no large dorsal blotches in S. caspia); branches of suborbital spine the same size (vs. the anterior one much shorter than posterior in S. caspia) (Kottelat & Freyhof 2007). Sayyadzadeh et al. (2018a) failed to find any spined loach in the examined materials as S. caucasica, so the data (morphologically and genetically) confirmed presence of only two Sabanejewia species in the Iranian drainage of the Caspian Sea basin.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on pages 16-17, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097
The bone microstructure of polar “hypsilophodontid” dinosaurs from Victoria, Australia
Creators: name: Woodward, Holly N.
name: Rich, Thomas H.
name: Rich, Patricia
Publisher: name: Swinburne
Year: 2024

description: High-latitude (i.e., "polar") Mesozoic fauna endured months of twilight and relatively low mean annual temperatures. Yet non-avian dinosaurs flourished in this taxing environment. Fossils of basal ornithopod dinosaurs ("hypsilophodontids") are common in the Early Cretaceous high-latitude sediments of Victoria, Australia, and four taxa have been described; although their ontogenetic histories are largely unexplored. In the present study, eighteen tibiae and femora were utilized in the first multi-specimen ontogenetic histological analysis of Australian polar hypsilophodontids. The sample consists of eleven individuals from the Flat Rocks locality (Late Valanginian or Barremian), and five from the Dinosaur Cove locality (Albian). In both groups, growth was most rapid during the first three years, and skeletal maturity occurred between five and seven years. There is a weak asymptotic trend in a plot of growth mark count versus femur length, with considerable individual variation. Histology suggests two genera are present within the Dinosaur Cove sample, but bone microstructure alone could not distinguish genera within the Flat Rocks sample, or across the two geologically separate (~ 26 Ma) localities. Additional histologic sampling, combined with morphological analyses, may facilitate further differentiation between ontogenetic, individual, and species variation.
Numerical and laboratory investigation of breaking of steep two-dimensional waves in deep water
Creators: name: Babanin, Alexander
name: Chalikov, Dmitry
name: Young, I. R.
name: Savelyev, Ivan
Publisher: name: Swinburne
Year: 2024

description: The paper extends a pilot study into a detailed investigation of properties of breaking waves and processes responsible for breaking. Simulations of evolution of steep to very steep waves to the point of breaking are undertaken by means of the fully nonlinear Chalikov-Sheinin model. Particular attention is paid to evolution of nonlinear wave properties, such as steepness, skewness and asymmetry, in the physical, rather than Fourier space, and to their interplay leading to the onset of breaking. The role of superimposed wind is also investigated. The capacity of the wind to affect the breaking onset is minimal unless the wind forcing is very strong. Wind is, however, important as a source of energy for amplification of the wave steepness and ultimately altering the breaking statistics. A detailed laboratory study is subsequently described. The theoretical predictions are verified and quantified. In addition, some features of the nonlinear development not revealed by the model (i.e. reduction of the wave period which further promotes an increase in steepness prior to breaking) are investigated. Physical properties of the incipient breaker are measured and examined, as well as characteristics of waves both preceding and following the breaker. The experiments were performed both with and without a superimposed wind, the role of which is also investigated. Since these idealized two-dimensional results are ultimately intended for field applications, tentative comparisons with known field data are considered. Limitations which the modulational instability mechanism can encounter in real broadband three-dimensional environments are highlighted. Also, substantial examination of existing methods of breaking onset detection are discussed and inconsistencies of existing measurements of breaking rates are pointed out.
KELAJAKDA: IOT QURILMA XAVFSIZLIGI YECHIMLARI SANOAT XAVFSIZLIGINI QANDAY BOSHQARISHI
Creators: name: Umarov, Begzod
name: Alimamadov, Nurmuhammad
Publisher: name: Zenodo
Year: 2025

description: Internetga ulangan IoT qurilmalarining ko'payishi qulaylik va samaradorlik uchun imkoniyatlar sonini keskin oshirdi, ammo bu xavfsizlik muammolari bilan birga keladi. Ma'lumotlarning buzilishiga olib keladigan IOT tizimidagi yangilanishlar va zaifliklarning etishmasligi, agar biz shaxsiy ma'lumotlarni va potentsial zararli aktyorlardan muhim infratuzilmani himoya qilishni maqsad qilsak, hal qilinadigan ba'zi asosiy sohalar bo'lib qolmoqda. Bunday IoT xavfsizlik muammolari va xavf-xatarlariga duch keladigan oqibatlar jiddiy bo'lishi mumkin, Ushbu maqolamda IoT qurilma xavfsizligi yechimlari sanoat xavfsizligini qanday boshqarishi mavzusida fikr yuritilgan.
Is the jet variability reflected in the BLR emission in FSRQs
Creators: name: Acosta-Pulido, Jose A.
name: Alemán-Martín, Iris M.
name: Otero-Santos, Jorge
Publisher: name: Zenodo
Year: 2024

description: We present an spectroscopic study of a sample of bright gamma-ray blazars. Our dataset includes spectra of a sample of about 10 targets, all of them Flat-Spectrum Radio Quasars (FSRQs). The spectra were obtained nearly periodically during the period from 2008 to 2018. Our aim is to search for variations in the luminosity of the emission lines,  related to variations in the continuum flux. We have used a fitting code (PyQSOFit) specifically developed to model the optical spectra of quasars. It permits to decompose the emission in different components, such as power-law continuum, host galaxy, FeII emission and line emission. Error parameter estimation is obtained running Monte-Carlo iterations. We will present preliminary results of the line measurements and its temporal variability. We  also present the correlation between line luminosity changes with the  optical flux variability and also with the gamma-ray luminosity. Most variability studies disregard the possible connection between the relativistic jet flares and the changes in the emission from the Broad Line Region. However, evidences for such events have been found in few individual FSRQs, ours is an attempt to extend the search in a larger sample and covering a more expanded time period.
Chromosomal sex determines gonadal sex, but it is not enough for male phenotype: Novel mutation in androgen receptor gene (C.237–239DEL AND C.1715A> G)
Creators: name: H. Alptekin
name: S. Barış
name: M. Yıldız
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Computational Biology
subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Chemistry
subject: Evolutionary Biology
subject: Pharmacology
subject: Physiology
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Medicine
subject: Biochemistry

description: Chromosomal sex determines gonadal sex, but it is not enough for male phenotype: Novel mutation in androgen receptor gene (C.237–239DEL AND C.1715A> G)
Hetero-structured lumpy nanoparticle conformal structure for high absorbance of ultrathin film amorphous silicon solar cells
Creators: name: Cai, Boyuan
name: Jia, Baohua
name: Gu, Min
Publisher: name: Swinburne
Year: 2024

description: We present a concept for enhancing the absorbance of amorphous-silicon solar cells by using hetero-structured nanoparticles consisting of dielectric core particles combined with small metallic surface nanoparticles half embedded in the core to harness both the scattering effect and the near field light concentration. Through optimising key parameters, including the relative distance of the nanoparticles to the solar cell, the radius ratio of the core to the surface nanoparticles, and the refractive index of the core particles, the short circuit current density in a 20 nm nanoparticle-integrated active layer is equivalent to that in a 300 nm flat active layer.
Modeling and Simulation of a Speed Breaker Power Generator
Creators: name: Omon, Favour
name: Ukpebor, Faithfulness
name: Ogiri, Caleb
name: Enoma, Nosakhare
Publisher: name: NIPES
Year: 2025

description: This study demonstrates the power generating performance and structural integrity of a speed breaker power generator, which is designed to generate power from road transportation. A model of the proposed system was designed with CATIA and simulated using ANSYS software. The system employs the principle of piezoelectric effect to convert the wasted kinetic energy of vehicles as they go over the speed breaker into useful electrical energy. The method adopted for this energy conversion utilizes the rack and pinion mechanism. Here, a rack and pinion are integrated beneath the speed breaker under the ground, in such a way that, as the vehicle passes over the speed bump, the linear displacement of the bump is converted by the rack into rotational motion In the pinion, and this was able to drive the shaft at the generator. Calculations and results show that the system could generate an average of 115.9 KW in 24 hours, with variation depending on the volume of traffic. Also, Structural analysis in the areas of stress levels and total deformation experienced by the system was carried out. The results obtained from ANSYS MECHANICAL justified the structural integrity of the system as safe for the stress and forces exerted on it by vehicular traffic. In conclusion, the power generated from this system proved capable of powering certain road electronic appliances like Streetlights, Traffic lights, and some LED displays, and this contributes to the development of sustainable energy resources, especially in Urban infrastructure.
On the variability of sea drag in finite water depth
Creators: name: Toffoli, Alessandro
name: Loffredo, L.
name: Le Roy, P.
name: Lefèvre, J. M.
name: Babanin, Alexander
Publisher: name: Swinburne
Year: 2024

description: The coupling between the atmospheric boundary layer and the ocean surface in large-scale models is usually parameterized in terms of the sea drag coefficient, which is routinely estimated as a function of mean wind speed. The scatter of data around such parametric dependencies, however, is very significant and imposes a serious limitation on the forecasts and predictions that make use of sea surface drag parameterizations. The analysis of an atmospheric and wave data set collected in finite water depth at the Lake George measurement site (Australia) suggests that this variability relates to a number of parameters at the air-sea interface other than wind speed alone. In particular, results indicate that the sea drag depends on water depth and wave steepness, which make the wave profile more vertically asymmetric, and the concentration of water vapor in the air, which modifies air density and friction velocity. These dependencies are used to derive parametric functions based on the combined contribution of wind, waves and relative humidity. A standard statistical analysis confirms a substantial improvement in the prediction of the drag coefficient and sea surface roughness when additional parameters are taken into account.
Bound Ratio Minimization of Filter Bank Frames
Creators: name: Chai, Li
name: Zhang, Jingxin
name: Zhang, Cishen
name: Mosca, Edoardo
Publisher: name: Swinburne
Year: 2024

description: This paper investigates and solves the problem of frame bound ratio minimization for oversampled perfect reconstruction (PR) filter banks (FBs). For a given analysis PRFB, a finite dimensional convex optimization algorithm is derived to redesign the subband gain of each channel. The redesign minimizes the frame bound ratio of the FB while maintaining its original properties and performance. The obtained solution is precise without involving frequency domain approximation and can be applied to many practical problems in signal processing. The optimal solution is applied to subband noise suppression and tree structured FB gain optimization, resulting in deeper insights and novel solutions to these two general classes of problems and considerable performance improvement. Effectiveness of the optimal solution is demonstrated by extensive numerical examples.
Identification and removal of reverberation in ultrasound imaging
Creators: name: Win, Kay. K.
name: Wang, Jing.
name: Zhang, Cishen
name: Ran Yang, Ran
Publisher: name: Swinburne
Year: 2024

description: This paper extends the results on reverberation identification and removal in ultrasound imaging to present an mathematical model for iterative representation of the echo time duration of reverberated radio frequency pulses. Experiment is conducted to show its usefulness in identification and removal of reverberation artifacts.
Children's and Adults’ Comfort Experience of Extra Seat Belts When Riding in the Rear Seat of a Passenger Car
Creators: name: Anna-Lisa Osvalder
name: Hansson, Ida
name: Bohman, Katarina
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences

description: Objective: The objective of this study was to explore passengers’ comfort experience of extra seat belts during on-road driving in the rear seat of a passenger car and to investigate how the use of extra belts affects children's and adults’ attitudes to the product.Methods: Two different seat belt systems were tested, criss-cross (CC) and backpack (BP), consisting of the standard 3-point belt together with an additional 2-point belt. In total, 32 participants (15 children aged 6–10, 6 youths aged 11–15, and 11 adults aged 20–79, who differed considerably in size, shape, and proportions) traveled for one hour with each system, including city traffic and highway driving. Four video cameras monitored the test subject during the drive. Subjective data regarding emotions and perceived discomfort were collected in questionnaires every 20 min. A semistructured interview was held afterwards.Results: All participant groups accepted the new products and especially the increased feeling of safety (P Conclusion: This exploratory study provided valuable knowledge from a user perspective for further development of new seat belt systems in cars. In addition to an increased feeling of safety, seat belt fit and comfort are supplementary influencing factors when it comes to gaining acceptance of new seat belt systems.
Experimental analysis of binary mixture model for ultrasound scattering from cancellous bone
Creators: name: Sockalingam, Uma
name: Zhang, Cishen
Publisher: name: Swinburne
Year: 2024

description: Ultrasound experiments were performed to collect in vivo calcaneal measurements in different orientations and at different frequencies and the experimental data were used for the evaluation and analysis of broadband ultrasound backscatter coefficients of the binary mixture model for the concellous bone. The results of experiments first revealed that the broadband ultrasound backscatter coefficient does not increase beyond 5 MHz frequency in accordance with prior research studies but contrary to the Binary Mixture model's cubic frequency dependence at all frequencies. Secondly, the experimental coefficients in different directions differ significantly. This is also contrary to the theoretical model's indifference to different directions.
Realizations of cascaded LTV mixed causal and anticausal systems
Creators: name: Chen, Xiaofang
name: Zhang, Cishen
name: Zhang, Jingxin
Publisher: name: Swinburne
Year: 2024

description: Models of anticausal systems have provided useful means for the analysis and understanding of system performance and properties and found applications in circuits, signal processing and dynamical systems. In this paper, structure and properties of linear time varying (LTV) mixed causal and anticausal systems are studied and state space realizations of cascaded LTV mixed causal and anticausal systems are presented. The conditions for the cascaded system realizations are related to time-varying Sylvester equations in terms of state-space matrices of the systems.
Cost–effectiveness analysis of simeprevir with daclatasvir for non-cirrhotic genotype-1b-naïve patients plus chronic hepatitis C
Creators: name: Gimeno-Ballester, Vicente
name: Mar, Javier
name: Miguel, Ramón San
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Background: The cost of interferon-free combination therapies remains high to provide widespread access to treatment, regardless of fibrosis stage. Aim: To estimate the cost–effectiveness of simeprevir/daclatasvir (SMV/DCV) therapy in treatment-naïve chronic hepatitis C genotype-1b patients with moderate fibrosis. Methods: A Markov model was developed to simulate the natural history of chronic hepatitis C progression. The model estimated lifetime healthcare costs and quality-adjusted life-years (QALY) for a cohort of patients from the Spanish National Healthcare System perspective. The cost–effectiveness threshold considered was €40,000/QALY. The treatment strategies analyzed were SMV/DCV, peginterferon/ribavirin/telaprevir, and peginterferon/ribavirin/boceprevir. A sensitivity analysis was carried out. Results: The incremental cost–effectiveness ratios of the SMV/DCV strategy were €23,774/QALY and €28,524/QALY compared with that of telaprevir or boceprevir triple therapy, respectively, for genotype-1b patients with moderate fibrosis. Conclusions: SMV/DCV combination compared with the standard of care previous to the arrival of second-generation direct-acting antivirals fell below generally accepted willingness-to-pay threshold. Results obtained should be supported by ongoing clinical trials.
On ultrasound image reconstruction by tissue density estimation
Creators: name: Huang, Zheng
name: Zhang, Jingxin
name: Zhang, Cishen
Publisher: name: Swinburne
Year: 2024

description: An inherent property of medical ultrasound imaging is the speckle noise that generally obscures the image and reduces the diagnostic image resolution and contrast. Consequently, substantial improvement of ultrasound images is an important prerequisite for ultrasound imaging. Some recent research has suggested that the spatial distribution of tissue densities may be used in ultrasound imaging to reconstruct images with fewer speckles. This new approach is based on the direct estimation of tissue density from the radio frequency echo signals received by ultrasound probe. This paper presents a mathematical analysis of this approach and derives a simplified model for issue estimation. This model simplifies the computation involved in density estimation and provides deeper insight into the problem. It shows that image reconstruction by tissue density estimation may have limited effect on speckle noise embedded in the RF echo signal. The analysis results are verified by numerical calculations and simulation examples.
Phosphoramidate-based peptidomimetic inhibitors of membrane type-1 matrix metalloproteinase
Creators: name: Mendes, Desiree E.
name: Wong-On-Wing, Annie
name: Berkman, Clifford E.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: Membrane-type I matrix metalloproteinases (MT1-MMP) is an enzyme critical to the remodeling and homeostasis of extracellular matrix, and when over expressed it contributes to metastasis and cancer cell progression. Because of its role and implication as a biomarker that is upregulated in various cancers, MT1-MMP has become an attractive target for drug discovery. A small pilot library of peptidomimetics containing a phosphoramidate core as a zinc-binding group was synthesized and tested for inhibitory potency against MT1-MMP. From this library, a novel two residue peptidomimetic scaffold was identified that confers potency against MT1-MMP at submicromolar concentrations. The results of this study confirm that for this scaffold, valine is favored as a P1 residue and leucine in the P1′ position. Furthermore, steric tolerance was observed for the N-terminus, thus implicating that a second-generation library could be constructed to extend the scaffold to P2 without concomitant loss of affinity within the MT1-MMP catalytic domain.