Additional file 1 of A low-inflammatory diet is associated with a lower incidence of diabetes: role of diabetes-related genetic risk
Creators: name: Yang, Rongrong
name: Lin, Jing
name: Yang, Hongxi
name: Dunk, Michelle M.
name: Wang, Jiao
name: Xu, Weili
name: Wang, Yaogang
Publisher: name: figshare
Year: 2024
Subjects: subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1: Method S1. Genetic risk score. Method S2. Inflammatory diet index score. Table S1. Single nucleotide polymorphisms used to build the genetic risk score for type 2 diabetes. Table S2. Examples of food items constituting the 39 food groups used to calculate the inflammatory diet index from the Oxford WebQ questionnaire of the UK Biobank. Table S3. Factor loadings of reduced rank regression dietary pattern. Table S4. Spearman correlation coefficients between individual food groups with high-sensitivity C-reactive protein concentrations. Table S5. Relative concentrations of plasma high-sensitivity C-reactive protein (hsCRP) across tertiles of the inflammatory diet index in test and retest groups. Table S6. Examples of food items from the Oxford WebQ included in the 18 food groups to calculate empirical dietary inflammatory pattern scores. Table S7. Basic-adjusted hazard ratios and 50th percentile differences of incident type 2 diabetes in relation to a low-inflammatory diet.  Table S8. Hazard ratios for the association between levels of genetic risk score and type 2 diabetes. Table S9. Hazard ratios of type 2 diabetes according to joint categories of the inflammatory diet index and genetic risk score.  Table S10. Hazard ratios for the association between low-inflammatory diet and type 2 diabetes stratified by genetic risk score. Table S11. Additive interaction between genetic risk score and inflammatory diet index for type 2 diabetes. Table S12. Spearman correlation coefficients between individual food groups and high-sensitivity C-reactive protein concentrations among participants with at least two 24-h dietary assessments. Table S13. Hazard ratios and 50th percentile differences of incident type 2 diabetes in relation to empirical dietary inflammatory pattern score. Table S14. Hazard ratios and 50th percentile differences of incident type 2 diabetes in relation to a low-inflammatory diet in normoglycemia and prediabetes groups after excluding missing values for covariates. Table S15. Hazard ratios for the association between low-inflammatory diet and type 2 diabetes stratified by sex. Table S16. Hazard ratios for the association between low-inflammatory diet and type 2 diabetes stratified by age. Table S17. Hazard ratios for the association between low-inflammatory diet and type 2 diabetes stratified by physical activity. Table S18. Mediating effects of high-sensitivity C-reactive protein in the association between inflammatory diet index and incident type 2 diabetes. Figure S1. Mediating effects of high-sensitivity C-reactive protein in the association between inflammatory diet index and incident type 2 diabetes.