cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Elachista echidnias Meyrick 1891
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista echidnias

description: Elachista echidnias Meyrick, 1891
Elachista echidnias Meyrick, 1891: 61.
Current status: Ascalenia echidnias (Meyrick, 1891) (Cosmopterigidae); Kasy (1973).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 176, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
Technical-Induced Hemolysis in Patients with Respiratory Failure Supported with Veno-Venous ECMO – Prevalence and Risk Factors
Creators: name: Lehle, Karla
name: Philipp, Alois
name: Zeman, Florian
name: Lunz, Dirk
name: Lubnow, Matthias
name: Wendel, Hans-Peter
name: Göbölös, Laszlo
name: Schmid, Christof
name: Müller, Thomas
Publisher: name: Universität Regensburg
Year: 2015
Subjects: subject: EXTRACORPOREAL MEMBRANE-OXYGENATION; NITRIC-OXIDE CONSUMPTION; ROTARY BLOOD PUMPS; FREE HEMOGLOBIN; IN-VITRO; CARDIAC-SURGERY; ADULTS; DAMAGE; PREDICTION; MORTALITY;
subject: 610 Medizin

description: The aim of the study was to explore the prevalence and risk factors for technical-induced hemolysis in adults supported with veno-venous extracorporeal membrane oxygenation (vvECMO) and to analyze the effect of hemolytic episodes on outcome. This was a retrospective, single-center study that included 318 adult patients (Regensburg ECMO Registry, 2009-2014) with acute respiratory failure treated with different modern miniaturized ECMO systems. Free plasma hemoglobin (fHb) was used as indicator for hemolysis. Throughout a cumulative support duration of 4,142 days on ECMO only 1.7% of the fHb levels were above a critical value of 500 mg/l. A grave rise in fHb indicated pumphead thrombosis (n = 8), while acute oxygenator thrombosis (n = 15) did not affect fHb. Replacement of the pumphead normalized fHb within two days. Neither pump or cannula type nor duration on the first system was associated with hemolysis. Multiple trauma, need for kidney replacement therapy, increased daily red blood cell transfusion requirements, and high blood flow (3.0-4.5 L/min) through small-sized cannulas significantly resulted in augmented blood cell trauma. Survivors were characterized by lower peak levels of fHb [90 (60, 142) mg/l] in comparison to non-survivors [148 (91, 256) mg/l, p <= 0.001]. In conclusion, marked hemolysis is not common in vvECMO with modern devices. Clinically obvious hemolysis often is caused by pumphead thrombosis. High flow velocity through small cannulas may also cause technical-induced hemolysis. In patients who developed lung failure due to trauma, fHb was elevated independantly of ECMO. In our cohort, the occurance of hemolysis was associated with increased mortality.
Validation of a German Version of the International Hip Outcome Tool 12 (G-iHOT12) According to the COSMIN Checklist
Creators: name: Baumann, Florian
name: Popp, Daniel
name: Müller, Karolina
name: Müller, Michael
name: Schmitz, Paul
name: Nerlich, Michael
name: Fickert, Stefan
Publisher: name: Universität Regensburg
Year: 2016
Subjects: subject: CROSS-CULTURAL ADAPTATION; QUALITY-OF-LIFE; FEMOROACETABULAR IMPINGEMENT; HEALTH-STATUS; CLINICALLY IMPORTANT; METHODOLOGICAL QUALITY; ARTHROSCOPIC SURGERY; GROIN DISABILITY; QUESTIONNAIRES; VALIDITY; Patient reported outcome (PRO); Hip arthroscopy; Femoro-acetabular impingement syndrome (FAI); Responsiveness; German International Hip Outcome Tool 12 (iHOT12); COSMIN checklist
subject: 610 Medizin

description: Background: Patient Reported Outcome (PRO) measurements have become an important tool to evaluate disease-related quality of life. The "International Hip Outcome Tool" (iHOT12) is a self-administered patient-reported outcome tool, which includes questions on the patient's symptoms, functional and sports limitations as well as social, emotional, and occupational limitations. The purpose of this study was to adapt and validate a German version of the iHOT12 according to the COSMIN checklist. Methods: In order to validate the German translation of the iHOT12, we conducted a prospective multicenter cohort study on patients with hip disorders and a score >= 4 on the modified Tegner Activity Scale (mTAS). The patients completed the German iHOT12 questionnaire and other functional scores (Hip Outcome Score, modified Tegner Activity Scale, EuroQol-5D) twice at intervals of at least two weeks. Evaluation of psychometric properties was conducted following the COSMIN checklist for validation of health status measurement instruments. The methodical testing for reliability included internal consistency, test-retest reliability, and measurement error. For testing of validity, we analyzed construct validity, hypotheses testing, interpretability and responsiveness. Results: Between December 2013 and December 2014, eighty-three consecutive patients completed both questionnaires and were available for data analysis. Cronbach's alpha was 0.94 (95 %-CI: 0.91, 0.95) confirming internal consistency and test-retest reliability of the iHOT-12 was high with an ICC = 0.94 (95 %-CI: 0.89, 0.97). All a priori hypotheses were confirmed. Further, no relevant floor-or ceiling effects occurred. The iHOT12 showed good responsiveness with a minimal important change (MIC) under 14 points. Conclusions: The German translation of the iHOT-12 is a reliable, valid, and responsive tool for the evaluation of disease-related quality of life in active patients with a hip disorder. We could show that the minimal important change, a change of health condition the patient discerns, is less than 14 points in the iHOT12 scale.
Grapsus granulosus H. Milne Edwards 1853
Creators: name: Ng, Ngan Kee
name: Rodríguez Moreno, Paula A.
name: Naruse, Tohru
name: Guinot, Danièle
name: Mollaret, Noémy
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Grapsidae
Grapsus
Grapsus granulosus

description: Grapsus granulosus H. Milne Edwards, 1853
(Fig. 3G)
Grapsus granulosus H. Milne Edwards, 1853: 135 [169].
CURRENT TAXONOMIC STATUS. — Grapsus granulosus H. Milne Edwards, 1853.
LECTOTYPE (by present designation). — MNHN-IU-2000-3417 (= MNHN-B3417), ♂ 64.2 × 71.9 mm, Red Sea, coll. M. Roux. — Original label: “ Grapsus granulosus, Mer Rouge, M. Roux ”.
PRESERVATION OF THE LECTOTYPE. — Dry. Carapace with a vertical crack on the right, a small chip off on the right posterior margin.
PARALECTOTYPES. — MNHN-IU-2000-3455 (= MNHN-B3455), 1 ♂ 61.8 × 67.0 mm, same data as lectotype. — MNHN-IU-2000-10937 (= MNHN-B10937), 1 ♂ 60.4 × 68.4 mm, 1 ♀ 54.1 × 59.2 mm, same data as lectotype.
PRESERVATION OF THE PARALECTOTYPES. — Dry.
REMARKS
The type locality is the Red Sea, and the collector “M. Roux” that is indicated on the label is likely J. L. F. P. Roux who collected material in the Mediterranean Sea and in the Near East (Bauchot et al. 1990, 1997; see Appendix). Material brought from the Red Sea by Roux has 1835 as entry date in the CAA. Thus, these samples unambiguously belong to the type series, and a lectotype can be designated.
According to Ng et al. (2008: 216, 218), Grapsus granulosus was often regarded as a junior synonym of Grapsus albolineatus (e.g. Banerjee 1960: 147, 153-154; Davie 2002: 213), but Crosnier (1965: 15, pl. 2, fig. 1) and Holthuis (1977: 147, 148) commented that it is a distinct species (see also Vannini & Valmori 1981; Zaouali et al. 2007).
description: Published as part of Ng, Ngan Kee, Rodríguez Moreno, Paula A., Naruse, Tohru, Guinot, Danièle & Mollaret, Noémy, 2019, Annotated type-catalogue of Brachyura (Crustacea, Decapoda) of the Muséum national d'Histoire naturelle, Paris. Part II. Gecarcinidae and Grapsidae (Thoracotremata, Grapsoidea), with an Appendix of pre- 1900 collectors, pp. 91-130 in Zoosystema 41 (7) on page 105, DOI: 10.5252/zoosystema2019v41a7, http://zenodo.org/record/3722522
Campyloneurus cingulicauda Enderlein 1920
Creators: name: Li, Yang
name: Achterberg, Cornelis Van
name: Chen, Xue-Xin
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Braconidae
Campyloneurus
Campyloneurus cingulicauda

description: Campyloneurus cingulicauda Enderlein, 1920
Campyloneurus cingulicauda Enderlein 1920: 105; Watanabe, 1934: 182, 1937: 20; Shenefelt, 1978: 1658; Chou, 1981: 73; Quicke & van Achterberg, 1990: 252; Kittel & Maeto, 2015: 203.
Biology. Unknown.
Distribution. China (Taiwan), Japan.
Note. The type series was collected from “Taihorin” (Taiwan) by H. Sauter. Enderlein (1920) listed only Taiwan as Watanabe (1934, 1937) and Chou (1981) till Kittel & Maeto (2015) reported it from Japan. No specimens were available for our study.
description: Published as part of Li, Yang, Achterberg, Cornelis Van & Chen, Xue-Xin, 2020, Two genera Campyloneurus Szépligeti and Iphiaulax Foerster in China, with the descriptions of fourteen new species (Hymenoptera, Braconidae, Braconinae), pp. 1-67 in Zootaxa 4884 (1) on page 10, DOI: 10.11646/zootaxa.4884.1.1, http://zenodo.org/record/4296207
Foliaro nº 29 (Vietnamio nº 2) (p. 1)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: Al dua mondmilito: La kauzoj.
Homosexualität - eine Herausforderung für Theologie und Seelsorge
Creators: name: Müller, Heinz Joachim
Publisher: name: Ordenskorrespondenz
Year: 1970

description: Ordenskorrespondenz, Bd. 29 (1988): Ordenskorrespondenz: Zeitschrift für Fragen des Ordenslebens, Band 29
Elachista emberizaepennella Duponchel 1843
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista emberizaepennella

description: Elachista emberizaepennella Duponchel, 1843
Elachista emberizae-pennella Duponchel, 1843, pl. 76, fig. 7.
Current status: Phyllonorycter emberizaepenella (Bouché, 1834) (Gracillariidae); De Prins & De Prins (2005).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 176, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
Combined rTMS treatment targeting the anterior cingulate and the temporal cortex for the treatment of chronic tinnitus
Creators: name: Kreuzer, Peter M.
name: Lehner, Astrid
name: Schlee, Winfried
name: Vielsmeier, Veronika
name: Schecklmann, Martin
name: Poeppl, Timm B.
name: Landgrebe, Michael
name: Rupprecht, Rainer
name: Langguth, Berthold
Publisher: name: Universität Regensburg
Year: 2015
Subjects: subject: TRANSCRANIAL MAGNETIC STIMULATION; COIL PREFRONTAL STIMULATION; RANDOMIZED CONTROLLED-TRIAL; MAJOR DEPRESSIVE DISORDER; FUNCTIONAL CONNECTIVITY; AUDITORY-CORTEX; FRONTAL-CORTEX; REPETITIVE TMS; TEMPOROPARIETAL JUNCTION; ANTIDEPRESSANT RESPONSE;
subject: 610 Medizin

description: Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a tinnitus treatment option. Promising results have been obtained by consecutive stimulation of lateral frontal and auditory brain regions. We investigated a combined stimulation paradigm targeting the anterior cingulate cortex (ACC) with double cone coil rTMS, followed by stimulation of the temporo-parietal junction area with a figure-of-eight coil. The study was conducted as a randomized, double-blind pilot trial in 40 patients suffering from chronic tinnitus. We compared mediofrontal stimulation with double-conecoil, (2000 stimuli, 10 Hz) followed by left temporo-parietal stimulation with figure-of-eight-coil (2000 stimuli, 1 Hz) to left dorsolateral-prefrontal-cortex stimulation with figure-of-eight-coil (2000 stimuli, 10 Hz) followed by temporo-parietal stimulation with figure-of-eight-coil (2000 stimuli, 1 Hz). The stimulation was feasible with comparable dropout rates in both study arms; no severe adverse events were registered. Responder rates did not differ in both study arms. There was a significant main effect of time for the change in the TQ score, but no significant time x group interaction. This pilot study demonstrated the feasibility of combined mediofrontal/temporoparietal-rTMS-stimulation with double cone coil in tinnitus patients but failed to show better outcome compared to an actively rTMS treated control group.
The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation
Creators: name: Loedige, Inga
name: Jakob, Leonhard
name: Treiber, Thomas
name: Ray, Debashish
name: Stotz, Mathias
name: Treiber, Nora
name: Hennig, Janosch
name: Cook, Kate B.
name: Morris, Quaid
name: Hughes, Timothy R.
name: Engelmann, Julia C.
name: Krahn, Michael P.
name: Meister, Gunter
Publisher: name: Universität Regensburg
Year: 2015
Subjects: subject: NEURAL STEM-CELLS; HUNCHBACK MESSENGER-RNA; SELF-RENEWAL; BINDING PROTEINS; PUMILIO; EXPRESSION; RECOGNITION; SUPPRESSOR; MICRORNAS; MODEL;
subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: TRIM-NHL proteins are conserved among metazoans and control cell fate decisions in various stem cell linages. The Drosophila TRIM-NHL protein Brain tumor (Brat) directs differentiation of neuronal stem cells by suppressing self-renewal factors. Brat is an RNA-binding protein and functions as a translational repressor. However, it is unknown which RNAs Brat regulates and how RNA-binding specificity is achieved. Using RNA immunoprecipitation and RNAcompete, we identify Brat-bound mRNAs in Drosophila embryos and define consensus binding motifs for Brat as well as a number of additional TRIM-NHL proteins, indicating that TRIM-NHL proteins are conserved, sequence-specific RNA-binding proteins. We demonstrate that Brat-mediated repression and direct RNA-binding depend on the identified motif and show that binding of the localization factor Miranda to the Brat-NHL domain inhibits Brat activity. Finally, to unravel the sequence specificity of the NHL domain, we crystallize the BratNHL domain in complex with RNA and present a high-resolution protein-RNA structure of this fold.
Elachista emyella Duponchel 1840
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista emyella

description: Elachista emyella Duponchel, 1840
Elachista emyella Duponchel, 1840: 548, pl. 309, fig. 6.
Current status: Coptotriche marginea (Haworth, 1828) (Tischeriidae); Diškus & Puplesis (2003).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 176, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
Grapsus grayi H. Milne Edwards 1853
Creators: name: Ng, Ngan Kee
name: Rodríguez Moreno, Paula A.
name: Naruse, Tohru
name: Guinot, Danièle
name: Mollaret, Noémy
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Grapsidae
Grapsus
Grapsus grayi

description: Grapsus grayi H. Milne Edwards, 1853
(Fig. 3H)
Grapsus Grayi H. Milne Edwards, 1853: 136 [170].
CURRENT TAXONOMIC STATUS. — Geograpsus grayi (H. Milne Edwards, 1853), accepted recombination (see A. Milne-Edwards 1873a: 288)
LECTOTYPE (by present designation). — MNHN-IU-2000-3421 (= MNHN-B3421), ♀ 34.1 × 42.1mm, Australia. — Original label: “ Grapsus grayi Edw., Australie, Museum Britannique!”.
PRESERVATION. — Dry. Carapace cracked on the gastric, cardiac regions; RP2 dactylus, RP3, RP4 meri and dactyli, LP2-LP4 carpi, meri and dactyli missing; pleonal somites 5, 6 damaged; telson missing.
REMARKS
Davie (2002: 213) indicated that the type status was uncertain. There is no doubt, however, that the above-mentioned female specimen was identified by H. Milne Edwards and corresponds to the type material. The mention on the label “Museum Britannique!” punctuated by an exclamation mark corresponds to the indication in the CAA of an exchange with the British Museum in 1849. According to Recommendation 73F of the Code, this specimen is hereby designated as lectotype.
description: Published as part of Ng, Ngan Kee, Rodríguez Moreno, Paula A., Naruse, Tohru, Guinot, Danièle & Mollaret, Noémy, 2019, Annotated type-catalogue of Brachyura (Crustacea, Decapoda) of the Muséum national d'Histoire naturelle, Paris. Part II. Gecarcinidae and Grapsidae (Thoracotremata, Grapsoidea), with an Appendix of pre- 1900 collectors, pp. 91-130 in Zoosystema 41 (7) on page 105, DOI: 10.5252/zoosystema2019v41a7, http://zenodo.org/record/3722522
title: Doña Fenix Alba. Nueva relacion, y curioso romance, en que se declaran los maravillos sucesos de una muy noble señora, llamada Doña Fenix Alba. Dase cuenta como habiéndola sacado un amante suyo de su casa con engaños, la llevó á un monte, en donde la quiso quitar su honor, y la dió puñaladas : como asimismo la venganza que tomó un leon de su alevoso amante, y el dichoso fin que tuvo la señora
Creators: name: Anonyme
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: (4) p. ; ill.
«Hoy, Señor, estadme atento,...»
description: Source: Bibliothèque patrimoniale Villon (Rouen), fonds Degrave, Mt m 20507-1-DS
Elachista epicoena Meyrick 1914
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista epicoena

description: Elachista epicoena Meyrick, 1914
Elachista epicoena Meyrick, 1914b: 196.
Currents status: Scythris epicoena (Meyrick, 1914) (Scythrididae); Bengtsson (2015).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 176, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
Grapsus lividus H. Milne Edwards 1837
Creators: name: Ng, Ngan Kee
name: Rodríguez Moreno, Paula A.
name: Naruse, Tohru
name: Guinot, Danièle
name: Mollaret, Noémy
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Grapsidae
Grapsus
Grapsus lividus

description: Grapsus lividus H. Milne Edwards, 1837
(Fig. 4A)
Grapsus lividus H. Milne Edwards, 1837: 85.
CURRENT TAXONOMIC STATUS. — Geograpsus lividus (H. Milne Edwards, 1837), accepted recombination (see Stimpson 1858: 101).
LECTOTYPE (by present designation). — MNHN-IU-2000-3426 (= MNHN-B3426), ♂ 16.4 × 19.1 mm, Antilles, Martinique, coll. M. Plée. — Original label: “ Grapsus lividus Edw. Martinique, M. Plée ”.
PRESERVATION OF THE LECTOTYPE. — Dry. RP 2 missing.
PARALECTOTYPES. — MNHN-IU-2000-1100 (= MNHN-B3426), 1 ♀ 13.7 × 15.8 mm, same data as lectotype. — MNHN-IU-2000-3427 (= MNHN-B3427), 1 ovig. ♀ 14.7 × 15.8 mm, 1 ♀ 13.0 × 16.9 mm, same data as lectotype.
PRESERVATION OF THE PARALECTOTYPES. — Dry.
REMARKS
Henri Milne Edwards (1837) indicated that the species was from the Antilles. His description mentioning at least two colour morphs (yellow with red marks; and almost entirely red) reveals that he has examined several specimens. The material collected by Plée in Martinique, his country of birth, most likely belongs to the type series according to the entry date “1826” of Plée’s material mentioned in the CAA (see also Bauchot et al. 1990: 117; Appendix). The specimen of “14 lignes” (1 ligne = 0.2255 cm), thus measuring 31.5 mm carapace length, cited by H. Milne Edwards (1837: 85) is no longer present in the MNHN collection, and all the MNHN specimens are smaller. The only male in the Plée material was selected as lectotype.
description: Published as part of Ng, Ngan Kee, Rodríguez Moreno, Paula A., Naruse, Tohru, Guinot, Danièle & Mollaret, Noémy, 2019, Annotated type-catalogue of Brachyura (Crustacea, Decapoda) of the Muséum national d'Histoire naturelle, Paris. Part II. Gecarcinidae and Grapsidae (Thoracotremata, Grapsoidea), with an Appendix of pre- 1900 collectors, pp. 91-130 in Zoosystema 41 (7) on page 106, DOI: 10.5252/zoosystema2019v41a7, http://zenodo.org/record/3722522
Elachista flavofasciella Duponchel 1843
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista flavofasciella

description: Elachista flavofasciella Duponchel, 1843
Elachista flavofasciella Duponchel, 1843: 516, pl. 89, fig. 12.
Current status: Oinophila v-flava (Haworth, 1828) (Tineidae); Joannis (1915).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 177, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
title: Die Implementation von epigenetischen Untersuchungen in die Diagnostik von Glioblastomen und deren klinischer Einfluss
Creators: name: Hellmeyer, Jan
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2024
Subjects: subject: 610 Medicine and health

description: Epigenetische DNA-Methylierungsanalysen (EPIC) ermöglichen eine präzisere Differenzierung von Glioblastomen (GBMs) und können histologisch niedriggradige Gliome aufdecken, die als GBM zu klassifizieren sind. Diese Studie untersucht den klinischen Nutzen von EPIC im Vergleich zur konventionellen neuropathologischen Diagnostik von GBMs in einer neurochirurgischen Klinik in Berlin. Insgesamt wurden 29 von 82 GBM-Patienten eingeschlossen und in Subgruppen unterteilt: Gruppe 1 (n=15) zeigte sowohl klassische pathologische als auch epigenetische GBM-Merkmale, während Gruppe 2 (n=12) epigenetische und pathologische Merkmale aufwies, die nicht übereinstimmten. Ein signifikanter Unterschied im Gesamtüberleben zeigte sich zwischen Gruppe 2 und Gruppe 1 (29,8 vs. 13,0 Monate). Die epigenetische Analyse beeinflusste die Diagnose bei einem Großteil der Patienten und identifizierte Subgruppen ohne typisches GBM-Methylierungsmuster, jedoch mit prolongiertem Überleben. Dies unterstreicht die Heterogenität und das unterschiedliche biologische Verhalten von Tumoren unter der gleichen Bezeichnung.
description: Abkürzungsverzeichnis ..... 1
Abbildungs- und Tabellenverzeichnis ..... 2
Vorwort ..... 3
1 Einleitung ..... 3
1.1 Von Begriff und Bezeichnung über Wahrnehmung bis Erkenntnis ..... 3
1.2 Glioblastom ..... 6
1.3 Historie und Änderung der Glioblastom Definition ..... 10
1.4 DNA-Methylierung und genomweite epigenetische DNA-Methylierungs-
Untersuchungen (EPIC) ..... 13
1.5 Therapie von Glioblastomen ..... 17
1.6 Fragestellung und Zielsetzung ..... 19
2 Methodik und Datenerhebung ..... 21
2.1 Datenakquise, Patientenselektion und Ein-/Ausschlusskriterien GBM ..... 21
2.2 Analyseparameter ..... 21
2.3 Bildgebende Analyse der Tumore ..... 22
2.4 Statistische und explorative Datenauswertung ..... 23
3 Ergebnisse ..... 24
3.1 Patientenkollektiv ..... 24
3.2 Konkordanz von klassisch pathologischer und epigenetischer Untersuchung und
Gruppenbildung ..... 27
3.3 Nicht klassifizierbare Fälle und erneute Klassifikation mit Version 12 ..... 30
3.4 Klinische und pathologische Charakteristika und Überlebenszeitanalyse ..... 31
3.5 Tumorlokalisation mittels der Brainlab Software Smart Brush ..... 38
3.6 Illustrative Fälle ..... 40
4 Diskussion ..... 45
4.1 Konkordanz und Diskordanz ..... 46
4.2 Überlebenszeitunterschiede ..... 50
4.3 Glioblastom Begriff ..... 53
4.4 Erkenntnisse aus abgeschlossenen Studien zum Einsatz von EPIC bei GBMs ..... 55
4.5 Limitationen ..... 59
4.6 Schlussfolgerung und Ausblick ..... 60
5 Literaturverzeichnis ..... 62
6 Danksagung ..... 73
7 Lebenslauf ..... 74
8 Appendix ..... I
Ethikvotum ..... I
Die Obergrenze in Vermögensangelegenheiten der Ordensgemeinschaften gemäß can. 638 § 3
Creators: name: Pfab, Josef
Publisher: name: Ordenskorrespondenz
Year: 1970

description: Ordenskorrespondenz, Bd. 29 (1988): Ordenskorrespondenz: Zeitschrift für Fragen des Ordenslebens, Band 29
Re-irradiating spinal column metastases using IMRT and VMAT with and without flattening filter - A treatment planning study
Creators: name: Dobler, Barbara
name: Khemissi, Amine
name: Obermeier, Tina
name: Hautmann, Matthias G.
name: Katsilieri, Zaira
name: Kölbl, Oliver
Publisher: name: Universität Regensburg
Year: 2016
Subjects: subject: UNFLATTENED PHOTON BEAMS; ARC THERAPY VMAT; STEREOTACTIC ABLATIVE RADIOTHERAPY; RADIATION-THERAPY; LINEAR-ACCELERATOR; MONTE-CARLO; NASOPHARYNGEAL CARCINOMA; DOSE DISTRIBUTIONS; PROSTATE-CANCER; REIRRADIATION;
subject: 610 Medizin

description: Background: The aim of this study was to investigate the potential of the flattening filter free (FFF) mode of a linear accelerator for intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) for patients with in-field recurrence of vertebral metastases. Methods: An Elekta Synergy Linac with Agility(TM) head is used to simulate the treatment of ten patients with locally recurrent spinal column metastases. Four plans were generated for each patient treating the vertebrae sparing the spinal cord: Dual arc VMAT and nine field step and shoot IMRT each with and without flattening filter. Plan quality was assessed considering target coverage and sparing of the spinal cord and normal tissue. All plans were verified by a 2D-ionisation-chamber-array, peripheral doses were measured and compared to calculations. Delivery times were measured and compared. The Wilcoxon test was used for statistical analysis with a significance level of 0.05. Results: Target coverage, homogeneity index and conformity index were comparable for both flat and flattening filter free beams. The volume of the spinal cord receiving the allowed maximum dose to keep the risk of radiation myelopathy at 0 % was at the same time significantly reduced to below the clinically relevant 1 ccm using FFF mode. In addition the mean dose deposited in the surrounding healthy tissue was significantly reduced in the FFF mode. All four techniques showed equally good gamma scores for plan verification. FFF plans required considerably more MU per fraction dose. Regardless of the large number of MU, out-of-field point dose was significantly lower for FFF plans, with an average reduction of 33 % and mean delivery time was significantly reduced by 22 % using FFF beams. When compared to IMRT FF, VMAT FFF offered even a reduction of 71 % in delivery time and 45 % in peripheral dose. Conclusions: FFF plans showed a significant improvement in sparing of normal tissue and the spinal cord, keeping target coverage and homogeneity comparable. In addition, delivery times were significantly reduced for FFF treatments, minimizing intrafractional motion as well as strain for the patient. Shortest delivery times were achieved using VMAT FFF. For radiotherapy of spinal column metastases VMAT FFF may therefore be considered the preferable treatment option for the combination of Elekta Synergy Linacs and Oncentra (R) External Beam v4.5 treatment planning system.
Autonomic and peripheral nervous system function in acute tick-borne encephalitis
Creators: name: Neumann, Bernhard
name: Schulte-Mattler, Wilhelm
name: Brix, Sophie
name: Pöschl, Peter
name: Jilg, Wolfgang
name: Bogdahn, Ulrich
name: Steinbrecher, Andreas
name: Kleiter, Ingo
Publisher: name: Universität Regensburg
Year: 2016
Subjects: subject: HEART-RATE-VARIABILITY; NILE-VIRUS-INFECTION; OF-THE-LITERATURE; VACCINATION; ILLNESS; Autonomic nervous system; central nervous system infection; encephalitis; inflammatory neuropathy; meningitis
subject: 610 Medizin

description: ObjectivesTick-borne encephalitis (TBE) is an emerging flaviviral zoonosis in Central and Eastern Europe. TBE can present as meningitis, meningoencephalitis, or meningoencephalomyelitis. Dysfunction of the autonomic (ANS) and peripheral motoric and sensory nervous system (PNS) might contribute to acute and long-term complications. We aimed to examine, whether the ANS and PNS are affected in acute TBE. MethodsFourteen patients with acute TBE, 17 with diabetic polyneuropathy (d-PNP), and 30 healthy controls (HC) were examined in our single-center, prospective study. ANS and PNS function was assessed by time- and frequency-domain parameters of the heart rate (HR) variability at rest and deep respiration, and by sural and tibial nerve neurography. Primary endpoint was the HR variability at rest measured by root mean square of the successive differences (RMSSD). Autonomic symptoms and quality of life (QoL) were assessed by questionnaires. ResultsTick-borne encephalitis patients had a lower RMSSD at rest (TBE 13.17.0, HC 72.7 +/- 48.3; P<0.001) and deep respiration (TBE 42.8 +/- 27.0, HC 109.7 +/- 68.8; P<0.01), an increased low-frequency to high-frequency power component ratio at rest (TBE 4.0 +/- 4.0, HC 0.8 +/- 0.5; P<0.001), and a higher minimal heart rate at rest (TBE 85.4 +/- 7.0, HC 69.5 +/- 8.5; P<0.001), all similar to patients with d-PNP, indicating sympathovagal imbalance with increased sympathetic activation. Compared to HC, sural and tibial nerve conduction velocities and action potential amplitudes were reduced, ANS symptoms were more frequent, and QoL was lower in patients with TBE. ConclusionsThe ANS and to a lesser degree the PNS are affected by acute TBE, which could potentially contribute to short- and long-term morbidity.
Elachista fonscolombella Duponchel 1840
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista fonscolombella

description: Elachista fonscolombella Duponchel, 1840
Elachista fonscolombella Duponchel, 1840: 549, pl. 309, fig. 7.
Current status: Lyonetia clerkella Linnaeus, 1758 (Lyonetiidae); Joannis (1915).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 177, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
title: Activité du port de Saint-Malo – 1752 – Uddevalla
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: minerais et métaux
subject: matériaux de construction

description: Cette fiche est issue de l’enquête menée par Jean Delumeau sur l’activité du port de Saint-Malo au 17e et 18e siècle. Cette fiche correspond à l’activité de l’année 1752 avec le port "Uddevalla"
description: Marchandises arrivées à Saint-Malo : fer ; planches
description: Catégories de marchandises arrivées à Saint-Malo : minerais et métaux ; matériaux de construction
description: Coverage: Grand commerce
description: Bibliographic citation: PAITRY, Daniel. Les Activités commerciales et la vie du port de Saint-Malo en 1752. DES : Histoire : Rennes : 1967 (Bibliothèque François-Lebrun, MH 1043)
description: date: Date de numérisation : 2021 à 2023
description: created: Années 1950-1960
Fluoxetine requires the endfeet protein aquaporin-4 to enhance plasticity of astrocyte processes
Creators: name: Neumann, Inga D.
name: Di Benedetto, Barbara
name: Malik, Victoria A.
name: Begum, Salina
name: Jablonowski, Lena
name: Gómez-González, Gabriela B.
name: Rupprecht, Rainer
Publisher: name: Universität Regensburg
Year: 2016
Subjects: subject: MAJOR DEPRESSIVE DISORDER; HIPPOCAMPAL NEUROGENESIS; PATHOLOGY; BRAIN; CYTOSKELETON; fluoxetine; astrocytes; glia-vasculature interface; plasticity; aquaporin-4
subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: Morphological alterations in astrocytes are characteristic for post mortem brains of patients affected by major depressive disorder (MDD). Recently, a significant reduction in the coverage of blood vessels (BVs) by aquaporin-4 (AQP-4)-positive astrocyte endfeet has been shown in the prefrontal cortex (PFC) of MDD patients, suggesting that either alterations in the morphology of endfeet or in AQP-4 distribution might be responsible for the disease phenotype or constitute a consequence of its progress. Antidepressant drugs (ADs) regulate the expression of several proteins, including astrocyte-specific ones. Thus, they may target AQP-4 to induce morphological changes in astrocytes and restore their proper shape or relocate AQP-4 to endfeet. Using an animal model of depression, rats selectively bred for high anxiety-like behavior (HAB), we confirmed a reduced coverage of BVs in the adult PFC by AQP-4-immunoreactive (AQP-4-IR) astrocyte processes with respect to non-selected Wistar rats (NAB), thereby validating it for our study. A further evaluation of the morphology of astrocyte in brain slices (ex vivo) and in vitro using an antibody against the astrocyte-specific cytoskeletal protein glial fibrillary acidic protein (GFAP) revealed that HAB astrocytes extended less processes than NAB cells. Furthermore, short-term drug treatment in vitro with the AD fluoxetine (FLX) was sufficient to increase the plasticity of astrocyte processes, enhancing their number in NAB-derived cells and recovering their basal number in HAB-derived cells. This enhanced FLX-dependent plasticity occurred, however, only in the presence of intact AQP-4, as demonstrated by the lack of effect after the downregulation of AQP-4 with RNAi in both NAB and HAB cells. Nonetheless, a similar short-term treatment did neither modulate the coverage of BVs with AQP-4-positive astrocyte endfeet in NAB nor in HAB rats, although dosage and time of treatment were sufficient to fully recover GFAP expression in HAB brains. Thus, we suggest that longer treatment regimes may be needed to properly restore the coverage of BVs or to relocate AQP-4 to astrocyte endfeet. In conclusion, FLX requires AQP-4 to modulate the plasticity of astrocyte processes and this effect might be essential to re-establish a functional glia-vasculature interface necessary for a physiological communication between bloodstream and brain parenchyma.
Phygadeuontinae Forster 1869
Creators: name: Reshchikov, Alexey
name: Santos, Bernardo F.
name: Liu, Jing-Xian
name: Barthélémy, Christophe
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae

description: Species inquirenda
Material examined
BRUNEI • 5 ♂♂; Labi; 200 m a.s.l.; mixed dipterocarp forest; Aug.–Sep. 1979; I. Gauld leg.; NHMUK • 1 ♂; Sep. 1982; N. Stork leg.; NHMUK.
PHILIPPINES • 2 ♂♂; Leyte Island, Bay Bay, Visca Forest; 5–13 Sep. 1980; L. Tuangga leg.; NHMUK.
Remarks
For eight male specimens, any morphological association with known females was not evident. Some of them could correspond to the males of P. angkor sp. nov., and at least some of these specimens seem to belong to a distinct taxon. Males of Palpostilpnus, however, show a complex dynamic of morphological variability, making its interpretation too risky with few specimens and without the corresponding female. Hence, the specimens in question are better interpreted, at least for now, as species inquirenda. Further studies with a refined population sampling of the genus should shed light on the interpretation of these specimens and of additional, undescribed taxa.
description: Published as part of Reshchikov, Alexey, Santos, Bernardo F., Liu, Jing-Xian & Barthélémy, Christophe, 2019, Review of Palpostilpnus Aubert (Hymenoptera, Ichneumonidae, Phygadeuontinae), with the description of ten new species, pp. 1-63 in European Journal of Taxonomy 582 on pages 57-58, DOI: 10.5852/ejt.2019.582, http://zenodo.org/record/3564360
Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer
Creators: name: Rascle, Anne
name: Pinz, Sophia
name: Unser, Samy
Publisher: name: Universität Regensburg
Year: 2016
Subjects: subject: HISTONE DEACETYLASE INHIBITOR; LONG-RANGE ENHANCERS; LEUKEMIA-CELLS; IN-VIVO; HEMATOPOIETIC-CELLS; BET BROMODOMAINS; EXPRESSION; IDENTIFICATION; PROLIFERATION; GENE; STAT5; c-Myc; BET; BRD2; Super-enhancer; Chromatin
subject: 610 Medizin

description: Background: c-Myc has been proposed as a putative target gene of signal transducer and activator of transcription 5 (STAT5). No functional STAT5 binding site has been identified so far within the c-Myc gene locus, therefore a direct transcriptional regulation by STAT5 remains uncertain. c-Myc super-enhancer, located 1.7 Mb downstream of the c-Myc gene locus, was recently reported as essential for the regulation of c-Myc gene expression by hematopoietic transcription factors and bromodomain and extra-terminal (BET) proteins and for leukemia maintenance. c-Myc super-enhancer is composed of five regulatory regions (E1-E5) which recruit transcription and chromatin-associated factors, mediating chromatin looping and interaction with the c-Myc promoter. Results: We now show that STAT5 strongly binds to c-Myc super-enhancer regions E3 and E4, both in normal and transformed Ba/F3 cells. We also found that the BET protein bromodomain-containing protein 2 (BRD2), a co-factor of STAT5, co-localizes with STAT5 at E3/E4 in Ba/F3 cells transformed by the constitutively active STAT5-1*6 mutant, but not in non-transformed Ba/F3 cells. BRD2 binding at E3/E4 coincides with c-Myc transcriptional activation and is lost upon treatment with deacetylase and BET inhibitors, both of which inhibit STAT5 transcriptional activity and c-Myc gene expression. Conclusions: Our data suggest that constitutive STAT5 binding to c-Myc super-enhancer might contribute to BRD2 maintenance and thus allow sustained expression of c-Myc in Ba/F3 cells transformed by STAT5-1*6.
Elachista gaunacella Duponchel 1843
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista gaunacella

description: Elachista gaunacella Duponchel, 1843
Elachista gaunacella Duponchel, 1843: 319, pl. 76, fig. 14.
Current status: Tischeria gaunacella (Duponchel, 1843) (Tischeriidae); Joannis (1915).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 177, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
Chondrocyclus Cole 2019, sensu lato
Creators: name: Cole, Mary L.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Architaenioglossa
Cyclophoridae
Chondrocyclus

description: Genus Chondrocyclus sensu lato Ancey, 1898
Chondrocyclus Ancey, 1898: 136
(type species by original designation: Cyclostoma convexiusculum Pfeiffer, 1855).
Chondrocyclus – Kobelt 1902: 230. — Connolly 1929: 239; 1939: 536. — Herbert & Kilburn 2004: 90
Key to genera within Chondrocyclus s.l.
1. Shell with axial periostracal costae usually expanded into spiral row(s) of broad-based flanges with pointed or rounded tips, radula with 2 or 3 large cusps on second lateral tooth, Cape peninsula to northern KwaZulu-Natal; or shell with axial periostracal costae expanded into spiral rows of hairs; operculum slightly concave, robust and dark brown, radula with 3 large cusps on second lateral tooth, Southwestern Cape only ........................................................ Chondrocyclus s.s. Ancey, 1898
– Shell with axial periostracal costae usually expanded into spiral rows of hairs, operculum flat, very fragile and pale corneous honey-brown, radula with two large cusps on second lateral tooth, Afromontane and southeast coast; or shell with axial periostracal costae slightly expanded at periphery, but not produced into hairs, radula with two large cusps on second lateral tooth, operculum with fringe consisting of bunches of short bristles, KwaZulu-Natal south coast only ........................ ............................................................................................................................ Afrocyclus gen. nov.
description: Published as part of Cole, Mary L., 2019, Revision of Chondrocyclus s. l. (Mollusca: Cyclophoridae), with description of a new genus and twelve new species, pp. 1-92 in European Journal of Taxonomy 569 on page 7, DOI: 10.5852/ejt.2019.569, http://zenodo.org/record/3517522
Campyloneurus gibbiventris Enderlein 1920
Creators: name: Li, Yang
name: Achterberg, Cornelis Van
name: Chen, Xue-Xin
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Braconidae
Campyloneurus
Campyloneurus gibbiventris

description: Campyloneurus gibbiventris Enderlein, 1920
Campyloneurus gibbiventris Enderlein, 1920: 104; Shenefelt, 1978: 1659; You, Quicke & Zhou, 1994: 121.
Biology. Unknown.
Distribution. China (Guangxi); India.
Note. You et al. (1994) reported the species from Guangxi (SW. China), but no specimens were available for our study.
description: Published as part of Li, Yang, Achterberg, Cornelis Van & Chen, Xue-Xin, 2020, Two genera Campyloneurus Szépligeti and Iphiaulax Foerster in China, with the descriptions of fourteen new species (Hymenoptera, Braconidae, Braconinae), pp. 1-67 in Zootaxa 4884 (1) on page 10, DOI: 10.11646/zootaxa.4884.1.1, http://zenodo.org/record/4296207
Enomiya-Lassalle, Hugo M.: ZEN-Weg zur Erleuchtung
Creators: name: Grunert, E.
Publisher: name: Ordenskorrespondenz
Year: 1970

description: Ordenskorrespondenz, Bd. 29 (1988): Ordenskorrespondenz: Zeitschrift für Fragen des Ordenslebens, Band 29
Impaired Recognition of Facially Expressed Emotions in Different Groups of Patients with Sleep Disorders
Creators: name: Crönlein, Tatjana
name: Langguth, Berthold
name: Eichhammer, Peter
name: Busch, Volker
Publisher: name: Universität Regensburg
Year: 2016
Subjects: subject: PSYCHIATRIC-DISORDERS; DEPRESSIVE SYMPTOMS; GENERAL-POPULATION; DAYTIME SLEEPINESS; APNEA; DEPRIVATION; INSOMNIA; STIMULI; DISTURBANCES; THERAPY;
subject: 610 Medizin

description: Introduction Recently it has been shown that acute sleep loss has a direct impact on emotional processing in healthy individuals. Here we studied the effect of chronically disturbed sleep on emotional processing by investigating two samples of patients with sleep disorders. Methods 25 patients with psychophysiologic insomnia (23 women and 2 men, mean age: 51.6 SD; 10.9 years), 19 patients with sleep apnea syndrome (4 women and 15 men, mean age: 51.9; SD 11.1) and a control sample of 24 subjects with normal sleep (15 women and 9 men, mean age 45.3; SD 8.8) completed a Facial Expressed Emotion Labelling (FEEL) task, requiring participants to categorize and rate the intensity of six emotional expression categories: anger, anxiety, fear, happiness, disgust and sadness. Differences in FEEL score and its subscales among the three samples were analysed using ANOVA with gender as a covariate. Results Both patients with psychophysiologic insomnia and patients with sleep apnea showed significantly lower performance in the FEEL test as compared to the control group. Differences were seen in the scales happiness and sadness. Patient groups did not differ from each other. Conclusion By demonstrating that previously known effects of acute sleep deprivation on emotional processing can be extended to persons experiencing chronically disturbed sleep, our data contribute to a deeper understanding of the relationship between sleep loss and emotions.
Elachista gibbiferella Zeller 1839
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista gibbiferella

description: Elachista gibbiferella Zeller, 1839
Elachista gibbiferella Zeller, 1839: 212.
Current status: Mompha lacteella (Stephens, 1834) (Momphidae); Koster & Sinev (2003).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 177, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
Petraster rigidus
Creators: name: Blake, Daniel B.
name: Lefebvre, Bertrand
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Echinodermata
Asteroidea
Euaxosida
Palasterinidae
Petraster
Petraster rigidus

description: Petraster rigidus (Billings, 1857)
(Fig. 1A)
Palasterina rigidus Billings, 1857: 291.
Petraster rigidus – Billings 1858: 80, pl. 10, fig. 3. — Spencer 1914: 40. — Schuchert 1915: 141, pl. 27, fig. 5. — Spencer 1927: 359. — Spencer & Wright 1966: 43. — Blake 2018: 28, pl. 4, fig. 5.
Palaeaster matutina – Hall 1868: 294.
TYPE MATERIAL. — Holotype. Canada • GSC 1401 a, Palasterina rigidus Billings, 1857; an incomplete, weathered specimen, only the oral surface exposed.
DIAGNOSIS. — Petraster species thought to exhibit two axillaries, one triangular and reaching the lateral margin, the second embedded; a single series of robust actinals well developed, it limited to disk.
TYPE LOCALITY AND HORIZON. — Cobourg beds, Ottawa, 45°026’37”N, 75°026’9”W; Trenton Limestone, Sandbianearly Katian.
DESCRIPTION
Petraster in which arms are moderately elongate, R reaching at least c. 20 mm. Inferomarginals robust, rectangular, relatively wide on disk, more nearly equidimensional on arm; some ossicles appear to bear accessory pustules.Two available interbrachia of the holotype differ, one with a well-defined triangular axillary and a possible second small axillary enclosed on disk adjacent to MAO. Actinals on disk in well-defined single series. Second interbrachium, ossicular arrangement poorly preserved and ill-defined. Axillary, actinals not clearly defined. Adaxials rectangular, transversely elongate.
REMARKS The poorly known type species is similar to other species assigned to the genus based on overall form and the limited data available on oral-surface expression, including inferomarginal shape, disk configuration, axillary, and actinal expressions. The diagnosis focuses on expression of the better-preserved interbrachium. The skeleton aboral to inferomarginals is almost unknown, the madreporite, axials, and MAO unknown. Posited presence of two axillaries serves to separate P. rigidus from other Petraster species except from P. kinahani, with specificities of expression differing between these two. The more lateral axillary is similar to the single axillary of P. crozonensis, the adjacent inferomarginals differ in outline. A few small elongate ossicles lateral to the inferomarginals of one arm appear unlike expressions among other species, although these ossicles as preserved appear dissimilar from traces exposed on other arms.
description: Published as part of Blake, Daniel B. & Lefebvre, Bertrand, 2024, Ordovician Petraster Billings, 1858 (Asteroidea: Echinodermata) and early asteroid skeletal differentiation, pp. 217-239 in Comptes Rendus Palevol 23 (17) on page 222, DOI: 10.5852/cr-palevol2024v23a17, http://zenodo.org/record/11387624