cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Editorial: Advanced approaches in pediatric clinical pharmacology
Creators: name: Diniz, Andrea
name: Karatza, Eleni
name: Allegaert, Karel
name: Sinha, Jaydeep
name: Al-Sallami, Hesham
Publisher: name: Frontiers
Year: 2024

description: Clinical pharmacology focuses on the impact of intrinsic and extrinsic factors on the inter-and intra-subject variability in drug exposure (pharmacokinetics) and response (pharmacodynamics, covering effects and side-effects). The aim hereby is to provide the right patient the right drug, using the right dose and at the right time. Traditional clinical pharmacology methods involve primarily performing large (randomized, placebo-controlled) trials to inform dosing strategies, including potential dose adjustments based on patients characteristics. Such studies are commonly conducted in homogeneous patient cohorts of adults. However, ethical challenges like the use of placebo or a control arm in an off-label pharmacotherapy setting, as well as logistical challenges like adequate number of study participants, and the fact that children are rather heterogeneous on age and weight are additional burdens in pediatric clinical pharmacology. Consequently, advanced approaches and additional creativity are needed to make pediatric drug development plans impactful on pediatric pharmacotherapy.
Strategy for aquatic ecological risk assessment at Teck Cominco's Kimberley operations, BC
Creators: name: Mann, Gary S. (Gary Seymour), 1966-
name: Baker, Randy F.
name: Allard, P. J.
name: Higgins, C. A.
name: Dawson, Bruce B.
Publisher: name: The University of British Columbia
Year: 2009

description: The overall objective of this predictive aquatic ecological risk assessment (ERA) is to assess contaminant-related risks after implementation of Teck Cominco’s closure plan for the site. The first stage of the ERA, problem formulation (PF), was conducted to identify the most likely risk drivers for the site to help focus subsequent aquatic ERA investigations. This paper summarizes the key findings of the PF and presents an overview of the main components of the aquatic ERA. The terrestrial component of the ERA is presented in a separate paper (Allard et al., 2004).
Genus Two Meromorphic Conformal Field Theory
Creators: name: Tuite, Michael P.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Quantum Algebra (math.QA)
subject: High Energy Physics - Theory (hep-th)
subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 81T40; 17B69 (Primary) 11F11; 11F46 (Secondary)

description: We construct the genus two (or two loop) partition function for meromorphic bosonic conformal field theories. We use a sewing procedure involving two genus one tori by exploiting an explicit relationship between the genus two period matrix and pinching modular parameters. We obtain expressions for the partition function for the chiral bosonic string, even rank lattice theories and self-dual meromorphic conformal field theories including the Moonshine Module. In particular, we find that for self-dual theories with central charge 24, the genus two partition function multiplied by a universal holomorphic function of the moduli is given by a meromorphic Siegel modular form of weight 2 where this universal function includes ghost contributions. We also discuss a novel expansion for certain Siegel modular forms.
description: 25 pages, AMS Latex2e, 2 figures, Talk presented at Workshop on Moonshine, CRM, Montreal, May 29 to June 4, 1999
New methodology for facilitating the food wastage quantification. Identifying gaps and data inconsistencies
Creators: name: Cobalea, Hector Barco
name: Garcia, Iraia Oribe
name: Viedma, Maria Virginia Vargas
name: Borges, Cruz Enrique
name: Andonegui, Cristina Martin
name: Vicario, Ainhoa Alonso
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: The work aims at providing a new methodology to facilitate the process of quantifying the food waste according to European standards all along the agrifood chain combining information that is becoming available at local level. This new methodology generates straightforward and easy-to-interpret results for the decision making process in the framework of the quantification of the food waste at local and supralocal scale and it provides adequate procedures which are easy adaptable to the specific circumstances in each municipality. Moreover, this method could have applications for larger territorial contexts, as the national scale, detecting possible points for improvement of the current official figures at this respect.
description: Accepted Manuscript version
title: Vierteljahresschrift für praktische Pharmazie 16. Jahrgang 1919
Creators: name: :None
Publisher: name: Deutscher Apotheker-Verein
Year: 1919
Subjects: subject: 615

description: Vierteljahresschrift für praktische Pharmazie 2. 1905 - 19. 1922: herausgegeben vom Deutschen Apotheker-Verein, vol. 16. 1919
Monte Carlo Simulations of Powder Diffraction at Time-of-Flight Neutron Sources
Creators: Li, Li
Publisher: name: Columbia University
Year: 2012
Subjects: Materials science

description: Measured powder diffraction patterns contain contributions from the sample and the instrument. Most available data analysis software operates on the measured data to extract sample parameters, however, few programs can take sample parameters and rigorously simulate the expected diffraction profile for a given instrument. In this work Monte Carlo methods, within the framework of McStas software, are used for the simulation of neutron diffraction at the SMARTS (Spectrometer for Materials Research at Temperature and Stress) diffractometer in the Los Alamos Neutron Science Center. The simulations include all the instrumental components, such as the moderator, guide system, collimator, detector banks and sample. The results of the simulations are in excellent agreement with the experimental data for different ideal powder samples. The simulations also yield information on the line broadening introduced into the diffraction profile as a function of energy and are used to predict the size and strain limit above which line broadening studies cannot be performed on this instrument. Theoretical derivations of line profile analysis are presented to provide an accurate explanation of the formation of diffraction peaks from the powder sample. This thesis demonstrates how rigorous scattering theory can be used to design optimal diffraction instruments.
Symbolic Dynamics Analysis of the Lorenz Equations
Creators: name: Hao, Bai-lin
name: Liu, Jun-xian
name: Zheng, Wei-mou
Publisher: name: arXiv
Year: 1997
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Recent progress of symbolic dynamics of one- and especially two-dimensional maps has enabled us to construct symbolic dynamics for systems of ordinary differential equations (ODEs). Numerical study under the guidance of symbolic dynamics is capable to yield global results on chaotic and periodic regimes in systems of dissipative ODEs which cannot be obtained neither by purely analytical means nor by numerical work alone. By constructing symbolic dynamics of 1D and 2D maps from the Poincare sections all unstable periodic orbits up to a given length at a fixed parameter set may be located and all stable periodic orbits up to a given length may be found in a wide parameter range. This knowledge, in turn, tells much about the nature of the chaotic limits. Applied to the Lorenz equations, this approach has led to a nomenclature, i.e., absolute periods and symbolic names, of stable and unstable periodic orbits for an autonomous system. Symmetry breakings and restorations as well as coexistence of different regimes are also analyzed by using symbolic dynamics.
description: 35 pages, LaTeX, 13 Postscript figures, uses psfig.tex. The revision concerns a bug at the end of hlzfig12.ps which prevented the printing of the whole .ps file from page 24
Uralophantes troitskensis Esyunin 1992
Creators: name: Gnelitsa, V. A.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Linyphiidae
Uralophantes
Uralophantes troitskensis

description: U. troitskensis Esyunin, 1992 (figs 5, 6, 9, 20–23, 28, 29)
D i s t r i b u t i o n. Russia: type locality: Cheliabinsk Region, Troitsk District, 10 km South of Berlin settlement, Troitskiy Wood-and-Steppe sanctuary, 53.9381° N, 61.2265° E (Esyunin, 1992); Orenburg Region, Sol-Iletsk District, Chybynda cavin, 50.9334° N, 54.8499° E (Esyunin, Tuneva & Farzalieva, 2007); Orsk (S. Esyunin, pers. comm.); Rostov Region, Ust’-Donetsk District, 12 km to the East of Veshenskaya settlement, Razdorskaya settlement vicinity, Atamanskaya gully, 47.5489° N, 40.6537° E (Ponomarev et al., 2017); Lebyazhinsky Khutor vicinity, 49.6040° N, 41.9143° E (Ponomarev et al., 2017) fig. 29.
Biology. The specimens were captured in litter of dry open places (Esyunin, 1992; Ponomarev et al., 2017), on the grass in patch forest with birch (Azheganova, 1951).
 C o m m e n t s: Data on U. troitskensis Esyunin, 1992 in both Cheliabinsk and Orenburg Regions were confirmed by Sergey Esyunin. For the rest points in Russia, the correctness of identification of U. troitskensis Esyunin, 1992 need corroboration.
 Discussion. Drawings of U. troitskensis male palp, although being somewhat schematic, nonetheless are accurate enough for comparison of two Uralophantes species. Judging from the figures certain palp parts of U. troitskensis differ in structure from those of U. ponticus sp. n. or entirely absent of all examined specimens of the new species. Beside that the palps of U. ponticus sp. n. from remote places (Sumy, Kherson, and Penza Regions) are quite conservative in their structure. Thus I consider U. ponticus sp. n. to differ considerably from U. troitskensis not representing a case of intraspecific variability of the last one.
 I thank Nina Polchaninova (Kharkiv, Ukraine), who kindly provided specimens from Luhansk Region (Ukraine) and Penza Region (Russia), and Sergey Esyunin (Perm, Russia) for unpublished data on U. troitskensis Esyunin, 1992 distribution.
description: Published as part of Gnelitsa, V. A., 2022, A New Uralophantes From The South Ukraine (Araneae, Linyphiidae, Ipaeinae), pp. 21-28 in Zoodiversity 56 (1) on page 27, DOI: 10.15407/zoo2022.01.021, http://zenodo.org/record/6456168
Raising the Profile of Research Software
Creators: name: Akhmerov, Anton
name: Cruz, Maria
name: Drost, Niels
name: Hof, Cees
name: Knapen, Tomas
name: Kuzak, Mateusz
name: Martinez-Ortiz, Carlos
name: Turkyilmaz-van der Velden, Yasemin
name: van Werkhoven, Ben
Publisher: name: Zenodo
Year: 2019
Subjects: Research Software
Data stewardship

description: Research software is fundamental to contemporary research, yet it does not receive the recognition it rightfully deserves. This needs to change, particularly in the context of the discussions around open science and reproducibility. We argue that if open science is to truly lead towards better, more transparent, and reproducible research, then research software needs to be treated in equal footing to research data and publications at the policy level. In this paper, we present a concrete followup to the DORA declaration in the form of recommendations for raising the profile of research software. We divide our recommendations into four categories: Software availability and quality, Software sustainability, Training, and Human capital. These recommendations provide steps for achieving recognition for research software as a fundamental and vital component of research.
Additional file 4: of Bispecific NKG2D-CD3 and NKG2D-CD16 fusion proteins for induction of NK and T cell reactivity against acute myeloid leukemia
Creators: name: MĂ¤Rklin, Melanie
name: Hagelstein, Ilona
name: Koerner, Samuel
name: Rothfelder, Kathrin
name: Pfluegler, Martin
name: Schumacher, Andreas
name: Grosse-Hovest, Ludger
name: Gundram Jung
name: Salih, Helmut
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Figure S4. Influence of blocking granule exocytosis on BFP-induced effector cell functionality (PDF 58 kb)
Volterra Distortions, Spinning Strings, and Cosmic Defects
Creators: name: Puntigam, Roland A.
name: Soleng, Harald H.
Publisher: name: arXiv
Year: 1996
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Cosmic strings, as topological spacetime defects, show striking resemblance to defects in solid continua: distortions, which can be classified into disclinations and dislocations, are line-like defects characterized by a delta function-valued curvature and torsion distribution giving rise to rotational and translational holonomy. We exploit this analogy and investigate how distortions can be adapted in a systematic manner from solid state systems to Einstein-Cartan gravity. As distortions are efficiently described within the framework of a $SO(3) {\rlap{$\supset$}\times}} T(3)$ gauge theory of solid continua with line defects, we are led in a straightforward way to a Poincaré gauge approach to gravity which is a natural framework for introducing the notion of distorted spacetimes. Constructing all ten possible distorted spacetimes, we recover, inter alia, the well-known exterior spacetime of a spin-polarized cosmic string as a special case of such a geometry. In a second step, we search for matter distributions which, in Einstein-Cartan gravity, act as sources of distorted spacetimes. The resulting solutions, appropriately matched to the distorted vacua, are cylindrically symmetric and are interpreted as spin-polarized cosmic strings and cosmic dislocations.
description: 24 pages, LaTeX, 9 eps figures; remarks on energy conditions added, discussion extended, version to be published in Class. Quantum Grav
Kondo model for the "0.7 anomaly" in transport through a quantum point contact
Creators: name: Meir, Yigal
name: Hirose, Kenji
name: Wingreen, Ned S.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Experiments on quantum point contacts have highlighted an anomalous conductance plateau at $0.7 (2e^2/h)$, with features suggestive of the Kondo effect. Here we present an Anderson model for transport through a point contact which we analyze in the Kondo limit. Hybridization to the band increases abruptly with energy but decreases with valence, so that the background conductance and the Kondo temperature $T_K$ are dominated by different valence transitions. This accounts for the high residual conductance above $T_K$. A spin-polarized current is predicted for Zeeman splitting $g^* μ_B B > k_B T_K,k_BT$.
description: 4 pages
Additional file 3: of Bispecific NKG2D-CD3 and NKG2D-CD16 fusion proteins for induction of NK and T cell reactivity against acute myeloid leukemia
Creators: name: MĂ¤Rklin, Melanie
name: Hagelstein, Ilona
name: Koerner, Samuel
name: Rothfelder, Kathrin
name: Pfluegler, Martin
name: Schumacher, Andreas
name: Grosse-Hovest, Ludger
name: Gundram Jung
name: Salih, Helmut
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Figure S3. Effects of NKG2D-CD3 on NKT cells (PDF 66 kb)
Additional file 5 of Consensus module analysis of abdominal fat deposition across multiple broiler lines
Creators: name: Yuan, Hui
name: Lu, Jun
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 5: Figure S3. Heatmaps of consensus modules correlated with abdominal fat deposition within GSE42980 or GSE49121.
Who chooses “healthy” meals? An analysis of lunchtime meal quality in a workplace cafeteria
Creators: name: Winthrop, Hilary M.
name: Bullock, Sally L.
name: Viera, Anthony J.
name: Ammerman, Alice S.
name: Yang, Yumei
name: Lin, Feng-Chang
name: Hales, Derek
Publisher: name: Springer Nature
Year: 2024

description: Background The workplace can play an important role in shaping the eating behaviors of U.S. adults. Unfortunately, foods obtained in the workplace tend to be low in nutritional quality. Questions remain about the best way to approach the promotion of healthy food purchases among employees and to what extent health promotion activities should be tailored to the demographic characteristics of the employees. The purpose of this study was to (1) assess the nutritional quality of lunchtime meal purchases by employees in cafeterias of a large organization, (2) examine associations between lunchtime meal quality selection and the demographic characteristics of employees, and (3) determine the healthfulness of foods and beverages offered in the cafeterias of this organization. Methods A cross-sectional analysis was conducted using secondary data from a food labeling study implemented in three worksite cafeterias. Demographic data was collected via surveys and meal data was collected using a photo capture system for 378 participants. The Healthy Eating Index 2015 (HEI-2015) was used to determine meal quality and a total score for the menu of options available in the cafeterias during the study period. Summary statistics were generated, and the analysis of variance (ANOVA) was used to compare the HEI-2015 scores between groups. Results The mean HEI-2015 total score for the menu items offered (n = 1,229) in the cafeteria during the study period was 63.1 (SD = 1.83). The mean HEI-2015 score for individual lunchtime meal observations (n = 378) was 47.1 (SD = 6.8). In general, HEI-2015 total scores were higher for non-smokers, individuals who self-identified as Asian, had higher physical activity levels, scored higher on numeracy and literacy assessments, and reported higher education levels, incomes, and health status. Conclusions The overall HEI-2015 scores indicate that the menu of options offered in the cafeterias and individual meal selections did not align with the Dietary Guidelines for Americans, and there were significant associations between average lunchtime meal quality scores and several demographic characteristics. These results suggest that healthy eating promotion activities in workplaces may need to be tailored to the demographic characteristics of the employees, and efforts to improve the food environment in the workplace could improve meal quality for all employees.
Moral Perception and Education in the World Today
Creators: Jung, Kyung Hwa
Publisher: name: Columbia University
Year: 2014
Subjects: Education--Philosophy

description: Moral perception is the non-inferential moral awareness immediately associated with moral emotion and action. Unfortunately, moral blindness, the incapability of moral perception, is frequently observed in the contemporary world. In order to account for the prevalence of moral blindness moral perception needs to be illuminated first, and the central purpose of this investigation is to elucidate the core property of moral perception. Moral perception has been denied by many modern moral theorists for a long time, but moral perception is an essential constituent of morality, which is also found in traditional moral philosophies, such as Aristotle's and Nietzsche's. Very recently, moral perception begins to be recognized as a way of moral awareness, but the number and diversity of research on it are still limited. Joining the recent effort to highlight moral perception this research attempts a new approach, phenomenological explication of moral perception, and Dewey's concept of perception and Heidegger's concept of thinking are mainly drawn on. For Dewey, perception presupposes the participatory subject who becomes to be related to the object or the situation, which is contrasted to the detached subject of recognition. Heidegger conceives thinking in a primordial sense which includes the perceptive level. Thinking begins with being inclined toward each other. On the ground of mutual inclination thinking becomes thanking to receive all that touch us. As Dewey and Heidegger similarly inform it, the essence of perception is the immediate connection between the perceiver and the perceived, and it is particularly distinct in moral perception. As an illustration of moral perception a Korean movie, Poetry by Chang-dong Lee, is introduced. Mija, the main character of the movie vividly embodies moral perception contrasted to moral blindness of the modern world. Considering the circumstance of modern world where the natural cultivation of moral perception is hindered, it is time to ask what kind of seeing and thinking should be cared about for education today.
The 1574 Lists of Wealden Ironworks
Creators: name: Cattell, C
Publisher: name: Archaeology Data Service
Year: 2021

description: Sussex Archaeological Collections, 117, 161-171
description: In 1574 there appeared a series of documents which form the most complete record of the extent of the Wealden iron industry for any one period in its history. The aim of this paper is to re-interpret the evidence contained in these documents and to pose questions that arise. Such questions have largely been neglected in the past. Answers to some of them have been attempted in the new light of knowledge shed upon the period. Those which remain unanswered, it is hoped, will stimulate further research by local historians and those interested in the Wealden iron industry as a whole. The prime concern has been with the problems of interpretation, rather than with the actual identification of sites, many of which can be, or have been identified beyond any element of doubt. There is some possibility that other sites, as yet unknown, remain to be found. Certain probable sites are indicated. That such a situation still exists after one hundred years of research into the industry can be illustrated by the discovery of the hitherto unknown sixteenth century site of Ardingly furnace.
More Powerful Than Dynamite: Radicals, Plutocrats, Progressives, and New York's Year of Anarchy
Creators: Jones, Thai Stein
Publisher: name: Columbia University
Year: 2012
Subjects: History
Anarchism
Progressivism (United States politics)

description: The year had opened with bright expectations, but 1914 quickly tumbled into disillusionment and violence. For John Purroy Mitchel, New York City's new "boy mayor," the trouble started in January, when a crushing winter caused homeless shelters to overflow and dozens of the city's homeless froze to death. By April, anarchist throngs had paraded past industrialists' mansions, and tens of thousands filled New York's Union Square demanding "Bread of Revolution."  Then, on July 4, 1914, a bomb destroyed a six-story Harlem tenement. It was the largest explosion the city had ever known. Among the dead were three bomb-makers; incited by anarchist Alexander Berkman, they had been preparing to dynamite the estate of John D. Rockefeller, Jr., son of a plutocratic dynasty and widely vilified for a massacre of his company's striking workers in Colorado earlier that spring. More Powerful Than Dynamite charts how anarchist anger, progressive idealism, and plutocratic paternalism converged in that July explosion.
Second order families of special Lagrangian 3-folds
Creators: name: Bryant, Robert L.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: Primary:32Q25, Secondary: 53C38

description: A second order family of special Lagrangian submanifolds of complex m-space is a family characterized by the satisfaction of a set of pointwise conditions on the second fundamental form. For example, the set of ruled special Lagrangian submanifolds of complex 3-space is characterized by a single algebraic equation on the second fundamental form. While the `generic' set of such conditions turns out to be incompatible, i.e., there are no special Lagrangian submanifolds that satisfy them, there are many interesting sets of conditions for which the corresponding family is unexpectedly large. In some cases, these geometrically defined families can be described explicitly, leading to new examples of special Lagrangian submanifolds. In other cases, these conditions characterize already known families in a new way. For example, the examples of Lawlor-Harvey constructed for the solution of the angle conjecture and recently generalized by Joyce turn out to be a natural and easily described second order family.
description: 36 pages, latex2e, some extra comments included in response to reader questions, many typos corrected, and important references added
Quantum Gravity and Turning Points in the Semiclassical Approximation
Creators: name: Keski-Vakkuri, Esko
name: Mathur, Samir D.
Publisher: name: arXiv
Year: 1996
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The wavefunctional in quantum gravity gives an amplitude for 3-geometries and matter fields. The four-space is usually recovered in a semiclassical approximation where the gravity variables are taken to oscillate rapidly compared to matter variables; this recovers the Schrodinger evolution for the matter. We examine turning points in the gravity variables where this approximation appears to be troublesome. We investigate the effect of such a turning point on the matter wavefunction, in simple quantum mechanical models and in a closed minisuperspace cosmology. We find that after evolving sufficiently far from the turning point the matter wavefunction recovers to a form close to that predicted by the semiclassical approximation, and we compute the leading correction (from `backreaction') in a simple model. We also show how turning points can appear in the gravitational sector in dilaton gravity. We give some remarks on the behavior of the wavefunctional in the vicinity of turning points in the context of dilaton gravity black holes.
description: 32 pages, 3 Postscript figures, uses epsf.tex and fps.sty, some discussion, references and Acknowledgements added, version to appear in Phys. Rev. D
Molybdenosis and moose at Highland Valley Copper
Creators: name: Swank, Carie-Ann
name: Gardner, Wendy
Publisher: name: The University of British Columbia
Year: 2009

description: In the fall of 2003, a study was conducted at Highland Valley Copper Mine (HVC) to determine if moose (Alces alces) grazing reclaimed mine tailing sites were at risk of molybdenosis – a molybdenum induced copper deficiency that affects ruminant animals. Past research at HVC indicates that the mine site has vegetation with higher molybdenum and copper concentrations then sites that do not have mining potential. To conduct this study, five 50m² plots were selected at each treatment site, HVC and the reference site (Wentworth Creek), and feces and vegetation were collected. All feces deposited (within a one-year period) were collected and the current years’ growth of shrubs, forbs, and grasses were sampled from five 1m² quadrats within each plot. The vegetation and feces were then analysed at the Agriculture and Agri-Food Canada research facility via the Dithiol Method for molybdenum and the Atomic Absorption Spectrophotometer Method for copper. Statistical analysis of the data indicated that molybdenum concentrations in feces and molybdenum and copper levels in the vegetation were higher at HVC then at the reference site. The copper concentration in the feces did not differ between sites. Thus, as moose are consuming more molybdenum and copper at HVC then at the reference site, they are at potential risk of molybdenosis. However, based on the extrapolation of results from the cattle studies conducted at HVC and the study on mule deer at Brenda Mines (as literature stating safe levels of molybdenum for moose is unavailable), moose are unlikely to display symptoms of molybdenosis from foraging at HVC.
Additional file 2: of Bispecific NKG2D-CD3 and NKG2D-CD16 fusion proteins for induction of NK and T cell reactivity against acute myeloid leukemia
Creators: name: MĂ¤Rklin, Melanie
name: Hagelstein, Ilona
name: Koerner, Samuel
name: Rothfelder, Kathrin
name: Pfluegler, Martin
name: Schumacher, Andreas
name: Grosse-Hovest, Ludger
name: Gundram Jung
name: Salih, Helmut
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Figure S2. Induction of leukemia cell lysis by BFP after depletion of effector cells (PDF 60 kb)
Turkozelotes kazachstanicus
Creators: name: Polchaninova, N.
name: Gnelitsa, V.
name: Terekhova, V.
name: Iosypchuk, A.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Gnaphosidae
Turkozelotes
Turkozelotes kazachstanicus

description: Turkоzelotes kazachstanicus (Ponomarev et Tsvetkov, 2006) * (figs. 9‒10)
M a t e r i a l e x a m i n e d. Zaporizhzhia Reg., Syvashyk, saline marshes, 10‒ 22.06.2019, 1 Ơ, 1 ♀.
 Distribution. Russia: Rostov-on-Don Reg. (Ponomarev & Dvadnenko, 2011 as T. mirandus). Kazakhstan: Atyrau and Kostanay reg. Azerbaijan: Nakhchivan AR (Ponomarev et al., 2021). Iran: Ilam Province (Zamani et al., 2018 as T. mirandus). Ukraine (first record): Zaporizhzhia Reg. (first record).
Note.A saline marshes specialist. Syvashyk bay shore is the westernmost known locality.
description: Published as part of Polchaninova, N., Gnelitsa, V., Terekhova, V. & Iosypchuk, A., 2021, New And Rare Spider Species (Arachnida, Araneae) From Ukraine, pp. 95-112 in Zoodiversity 55 (2) on page 100, DOI: 10.15407/zoo2021.02.095, http://zenodo.org/record/6455874
Quasi ballistic magnetization reversal
Creators: name: Schumacher, H. W.
name: Chappert, C.
name: Sousa, R. C.
name: Freitas, P. P.
name: Miltat, J.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We demonstrate a quasi ballistic switching of the magnetization in a microscopic mag-neto resistive memory cell. By means of time resolved magneto transport we follow the large angle precession of the free layer magnetization of a spin valve cell upon applica-tion of transverse magnetic field pulses. Stopping the field pulse after a 180 degree precession rotation leads to magnetization reversal with reversal times as short as 165 ps. This switching mode represents the fundamental ultra fast limit of field induced magnetization reversal.
description: 16 pages, 4 figures, experimental. submitted to Phys. Rev. Lett
Morocco: Multilingualism, Cultural Identity, and Mathematics Education, Post-French Protectorate, a Historical Perspective
Creators: Aqil, Moulay Driss
Publisher: name: Columbia University
Year: 2019
Subjects: Mathematics--Study and teaching
Group identity
Multilingualism
Education
French colonies

description: Through a historical perspective, this study highlighted significant events and milestones about multilingualism, cultural identity, and mathematics education in Morocco pre-, during, and post-French Protectorate. Prior research in this area has typically focused on the effect on education of multilingualism and cultural identity in general, involving mathematics education only in passing. This study’s purpose was to explore Morocco’s attempt to restore its cultural identity post-French Protectorate and how that attempt influenced the Moroccan mathematical educational system. In addition, this study focused on the Arabic and indigenous Berber (Tamazight) languages of instruction in mathematics in Morocco to investigate if teaching and learning mathematics in the Arabic and Tamazight languages in secondary schools is preparing students adequately for the tertiary level. Finally, this study attempted to see if multilingualism and cultural identity are at the heart of mathematical educational reform and to offer insight into the state of mathematics education reforms suggested by the Moroccan government to remedy this challenge. In order to develop a comprehensive picture of how multilingualism and cultural identity have historically influenced the mathematics education system in Morocco and answer the research questions of the study, a historical research methodology was employed based on views of numerous scholars about bilingual education, cultural identity, diglossia, and how they affect cognition and learning/teaching of mathematics. Supplementary knowledge about students’ achievements, retention, and dropout rates at the primary, secondary, and tertiary levels by gender and grade were acquired and supported by quantitative available data in the official archives supplied by the Ministry of Education, UNESCO, and other organizations. After independence, the establishment of an educational system that would take into consideration the deeply rooted Arab-Islamic culture and language and, at the same time, make use of the imposed Western system was a priority. Arabisation received more attention, and the selection of Arabic as a national language was a form of countering the colonizer’s language policy. Morocco has a particularly complex language situation, where French predominates in most postsecondary institutions, despite attempts to restore Arabic. The indigenous Berber language also plays a role in local culture and education. This work reveals a great number of attempted reforms by the Moroccan government and also demonstrates serious flaws in recent past attempts to reconcile the language issues, but offer ways forward in relation to mathematics instruction.
Untersuchung der Gauß-Verteilung in einem konvektionsauflösenden 1000-member Ensemble
Creators: name: Sirbescu, Marco
Publisher: name: Zenodo
Year: 2019

description: Eine häufige Annahme in der Datenassimilation ist es, von Gaußverteilten Variablen und Fehlern auszugehen. Diese Arbeit beleuchtet erstmals genauer die Häufigkeitsverteilung des Luftdrucks, der zonalen Windgeschwindigkeit, des Niederschlags, der Radarreflektvität, der Temperatur sowie der spezifischen Feuchte anhand von zwei Vorhersagen vom 29.05.2016 und deren zeitliche Entwicklung im konvektionsauflösenden SCALE-RM 1000-member Ensemble. Die Verteilung des Bodendrucks und der zonalen Windgeschwindigkeit ist im Allgemeinen Gaußverteilt, während diese Annahme auf die Verteilung von Niederschlag und Radarreflek- tivität nicht zutrifft. Die Verteilungen dieser Größen zeigen keine große Sensitivität gegenüber der Vorhersagezeit oder der Domaingröße. Grundsätzlich begünstigen kurze Vorhersagezeiten und Untersuchungsgebiete mittlerer Größe, mit bis zu 5400 Gitterpunkten, die Ausbildung von Gauß -Verteilungen.

Für stets Gaußverteilte bzw. nie Gaußverteilte Größen ist eine Ensemblegröße von 20 Membern zur Bestimmung der Verteilung ausreichend. Dahingegen ist die Charakterisierung der Verteilung von spezifischer Feuchte und Temperatur erst ab 100-membern zuverlässig möglich. Vorzugsweise werden diese Variablen jedoch mit 200 Ensemblemember untersucht. Das 1000-member Ensemble wird als Referenz betrachtet.

Die Verteilung der spezifischen Feuchte und der Temperatur in einer Höhe von 2m ist bei geeigneter Vorhersagezeit und Domaingröße Gaußverteilt, wohingegen in 500 hPa meist nur die Temperatur Gaußverteilt ist. Dabei wurde die Interaktion von Temperatur, spezifischer Feuchte und Bewölkungsgrad in einem Untersuchungsgebiet mittlerer Größe als entschei- dend für das Auftreten von Gauß-Verteilungen oder bimodalen Verteilungen identifiziert. Der Einfluss von Wolken lässt sich besonders gut bei bimodalen Verteilungen sehen. Ursachen dieser Verteilungen sind Gebiete mit starken Temperaturgradienten, bedingt durch Land-See-Systeme, diverser Topographie und vor allem den Bewölkungsgrad.
Additional file 1 of Use of dexmedetomidine in patients with sepsis: a systematic review and meta-analysis of randomized-controlled trials
Creators: name: Zhang, Ting
name: Mei, Qimin
name: Dai, Shabai
name: Liu, Yecheng
name: Zhu, Huadong
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1. PRISMA checklist. Sample Search Strategy: Appendix S1 to Appendix S5.e-Table S1: mortality timeline. Appendix S6. Summary of Findings Table: e-Table S2 to e-Table S8. Appendix S6. Summary of Findings Table: e-Table 2 to e-Table 8. e-Table S9: Levels of IL-6 and TNF-α changes at 24 h. e-Table S10: Levels of Alanine Transaminase and Creatinine changes at 24 he-Figure 1: Summarizes the RoB for each individual trial. e-Figure 2: e-Figure_2 Publish bias assessments. e-Figure 3: Effect of dexmedetomidine on mortality. e-Figure 4: Sensitivity analysis based on mortality . e-Figure 5: Effect of dexmedetomidine on ICU stays. e-Figure 6: Forest plot of duration of mechanical ventilation. e-Figure 7: Forest plot of ventilator-free days. e-Figure S8: Effect of dexmedetomidine on levels of IL-6. e-Figure 9: Effect of dexmedetomidine on levels of TNF-α. e-Figure 10: Effect of dexmedetomidine on levels of ALT and Cr. e-Figure 11: Forest plot of Incidence of delirium. e-Figure 12: Forest plot of Incidence of adverse events.
Additional file 1: of Bispecific NKG2D-CD3 and NKG2D-CD16 fusion proteins for induction of NK and T cell reactivity against acute myeloid leukemia
Creators: name: MĂ¤Rklin, Melanie
name: Hagelstein, Ilona
name: Koerner, Samuel
name: Rothfelder, Kathrin
name: Pfluegler, Martin
name: Schumacher, Andreas
name: Grosse-Hovest, Ludger
name: Gundram Jung
name: Salih, Helmut
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Figure S1. Combination of NKG2D-CD3 & NKG2D-CD16 in leukemia cell lysis (PDF 67 kb)
More Problematic than the Newcomb Problems: Extraordinary Cases in Causal Decision Theory and Belief Revision
Creators: Listwa, Daniel
Publisher: name: Columbia University
Year: 2015
Subjects: subject: Philosophy
subject: FOS: Philosophy, ethics and religion

description: In this paper, I turn toward the types of cases regarding which I-CDT and K-CDT come apart. In particular, I present two novel examples, which, I argue, display I-CDT to be superior to K-CDT. The first, the “Chancy Dog Problem,” follows the form of a scenario that is explored in Rabinowitz [2009] and shows I-CDT to give what I argue to be the correct recommendation in a chancy universe, where K-CDT gives the incorrect one. I explain this difference as stemming from the fact that conditionalization shifts credences too much, adjusting beliefs as though the oracle provides more information that it actually does. Specifically, conditionalization leads one to revise one’s beliefs as though the oracle’s information tells you not only what will happen, but also what will happen were you to do something other than what you will actually do. Imaging by shifting credence directly to the nearest compatible world avoids this fault by making the minimal adjustment to one’s beliefs to maintain consistency. The other example, the “Faulty Signal Problem,” is structurally similar to a problematic scenario discovered by Collins [forthcoming], which reveals K-CDT to fail to provide a recommendation even in certain nonchancy universes, particularly those that exhibit what I refer to as “counterfactual asymmetries.” I explain why cases of counterfactual asymmetry present a particular difficulty for K-CDT, as a theory which utilizes conditionalization as a method of updating on the information provided by taking a certain action-proposition to be true. In both evidential and causal decision theory, one considers an action by revising one’s belief to suppose the action-proposition is true. The evidential decision theorist does this revision by hypothesizing that she receives, in an indicative fashion, news that the proposition is true. One who uses K-CDT does the same, but holds fixed certain causal beliefs. The Newcomb Problem and other such cases have shown, I believe, EDT to be wrong, but the problems I will present will show this second suggestion to be wrong as well. Instead, the correct form of decision theory requires an agent to subjectively place herself in different circumstances, even if such circumstances do not agree with facts she believes to be true. Deliberating in this subjunctive sense, as I discuss, requires imaging.
Ultrahigh energy cosmic rays from a nearby extragalactic source in the diffusive regime
Creators: name: Mollerach, Silvia
name: Roulet, Esteban
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We study the effects that the diffusion of the cosmic rays in the magnetic field of the Local Supercluster can have on the spectrum of a nearby extragalactic source at ultrahigh energies. We find that the strong enhancement of the flux below the energy at which the transition between the diffusive and quasirectilinear regimes takes place, as well as the suppression at lower energies associated with a finite source age, can help to explain the observed features of the cosmic-ray spectrum and the composition. Scenarios are discussed in which a nearby extragalactic source with mixed composition and rigidity-dependent spectrum accounts for most of the observed cosmic rays at energies above a few EeV while the rest of the extragalactic sources lead to a diffuse flux that dominates at lower energies and down to $\sim 0.1$~EeV. The nearby source can also naturally account for the dipolar anisotropy measurements above 4~EeV, and these measurements can also help to constrain its evolution with redshift.
description: matches published version
title: Applying Action-Research to the analysis of motivation in FL learners: A case study on the translation of motivated behaviour into Italian teaching practice
Creators: name: Baglioni, Carolina Giorgia
Publisher: name: University of Glasgow
Year: 2025

description: The importance of motivation in learning a Foreign Language (FL) is well established, but less widely explored is whether understanding learners’ motivation can meaningfully inform curriculum design. This study is informed by Action-Research, a model built on immediate and ongoing reflections on educational practice (Leitch & Day, 2000); it relies on the fundamental notion in language education that motivation and successful learning outcomes are closely interrelated, as extensive research has shown. However, what the present study aims to explore further is whether tracking motivation – through questionnaires including an initial needs analysis, learning diaries, interviews and Focus Groups – could inform curriculum development of an Italian FL course. Participants (n=9) were complete beginners in Italian, who provided feedback on their learning experiences, and their motivations, expectations and needs within the microcosm of this Italian class. Such data informed the development of the curriculum design for the whole duration of the Italian course and represented at the same time a precious resource for the teacher-researcher to understand the motivation of the learner-participants.

It is intended that the findings will contribute to the ongoing field of investigation on those learning LOTEs’ (Languages Other Than English) and their motivation, with a specific focus on improved materials design. Furthermore, the present study aims to explore a learnercentred approach within an Italian learning process, aligning therefore with other current educational frameworks in the field, such as and Identity informed Curriculum Design and Negotiated Syllabus.
Mosaicism and the genetic architecture of congenital heart disease
Creators: Hsieh, Alexander Lin
Publisher: name: Columbia University
Year: 2020
Subjects: subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Congenital heart disease
subject: Mosaicism
subject: Diseases--Causes and theories of causation

description: Congenital heart disease (CHD) is characterized by structural defects of the heart and great vessels. It is the most common birth defect, affecting an estimated 1% of live births, and is the leading cause of mortality among birth defects. Despite recent progress in genetic research, more than 50% of CHD cases remain unexplained. An estimated 23% are due to aneuploidies and copy number variants and up to 30% has been attributed to de novo variation, though that number ranges between 3-30% depending on CHD complexity. The contribution of somatic mosaicism, or de novo genetic mutations arising after oocyte fertilization, to congenital heart disease (CHD) is not well understood due to limitations in sample size, detection method, and validation rate. Further, the relationship between mosaicism in blood and cardiovascular tissue has not been determined. We developed a computational method, Expectation-Maximization-based detection of Mosaicism (EM-mosaic), to analyze mosaicism in exome sequences of 2530 CHD proband-parent trios. EM-mosaic accurately detected 309 mosaic mutations in blood, with 85 of 94 (90%) candidates tested independently confirmed. We found twenty-five likely damaging mosaics in plausible CHD-risk genes, affecting 1% of our cohort. Variants in these genes predicted as damaging had higher variant allele fraction than benign variants, suggesting a role in CHD. The frequency of protein-coding mosaic variants detectable in blood was 0.122 or roughly 1 in 8 individuals. Analysis of 66 individuals with matched cardiac tissue available revealed both tissue-specific and shared mosaicism, with shared mosaics generally having higher allele fraction. CHD patients often present with comorbid cardiac and extracardiac anomalies that further their impact quality of life. Neurodevelopmental disorders (NDDs) are especially prevalent in CHD cases compared to the general population, yet the underlying genetic causes remain poorly explained. Further, patients with single ventricle defects undergoing surgery often later develop arrhythmias and experience worsening ventricular function. We used a statistical approach to dissect the association between de novo variation and these clinical outcomes and found that pleiotropic mutations contribute a large fraction of the risk of acquiring NDD and abnormal ventricular function phenotypes in CHD patients. We developed a proof-of-concept rare variant risk score that combines information from de novo, rare transmitted, and copy- number variants and show that prediction of outcomes such as NDD can be improved, especially in complex CHD cases.