cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ALMA Reveals the Interstellar Medium Dynamics of Hyper-luminous Obscured Quasars
Creators: name: Tanio Diaz-Santos
Publisher: name: Zenodo
Year: 2020

description: One of the most important results obtained from the WISE mission was the discovery of a previously unknown population of high redshift Hot, Dust Obscured Galaxies (Hot DOGs) at z > 1. The extreme bolometric luminosities of Hot DOGs, Lbol > 10^13 Lsun, are thought to be powered by accretion onto supermassive black holes (SMBH) buried under enormous amounts of gas and dust, effectively making them hyper-luminous obscured quasars. Depending on the time available, in this talk I will report the latest results of several follow up studies focused on the investigation of the interstellar medium and kinematic properties of Hot DOGs, including their SMBHs and host galaxies. I will pay special attention to the results of an ALMA pilot survey of the [CII] line at 158um in a sample of 7 Hot DOGs at z ~3 to 4.6. While these systems are thought to be at a key stage of their evolution, where the quasar is about to blow out its dusty cocoon, the ALMA observations show a diversity of morphologies and complex kinematic structures, surprisingly pointing to a non-unique dynamical state. In addition, ALMA has also provided us with a closer look to WISE 2246-0526, the most luminous galaxy known, where recent, deep observations of its FIR dust continuum emission reveal multiple companion galaxies and resolved filamentary structures connecting them to the central object, suggesting that accretion of neighbor galaxies may be a key mechanism through which the most luminous galaxies in the Universe grow their stellar mass, as well as feed and obscure their central SMBHs.
Comparison of statistical methods for extrapolating survival in previously untreated diffuse large B-cell lymphoma: results based on the POLARIX study
Creators: name: Ho, Rodrigo S.
name: Launonen, Aino
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The ongoing Phase III randomized POLARIX study (GO39942; NCT03274492) demonstrated significantly improved progression-free survival (PFS) with polatuzumab vedotin plus rituximab, cyclophosphamide, doxorubicin and prednisone (Pola-R-CHP) versus rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with previously untreated diffuse large B-cell lymphoma (DLBCL). We compared statistical methodologies to extrapolate long-term PFS data from POLARIX. This analysis explored four different approaches to extrapolate the POLARIX data: standard parametric survival, mixture-cure, landmark, and spline models. The resulting extrapolation curves were validated via comparison with the corresponding Kaplan–Meier (KM) curves from POLARIX and the POLARIX-like population of the Phase III GOYA study (NCT01287741; R-CHOP arm). The R-CHOP PFS KM curve from the GOYA validation set was well aligned with the POLARIX KM curve. As we anticipated that PFS in POLARIX would evolve similarly to that of GOYA, the data from GOYA were used to externally validate the extrapolated modelling results. While all four statistical methods were able to fit the data to the POLARIX KM curve, the mixture-cure model was the most accurate in predicting long-term PFS in the GOYA external validation set. In the mixture-cure model, generalized gamma distribution estimated 64% (95% confidence intervals [CI]: 56–71%) of patients to have long-term remission in the R-CHOP arm of POLARIX and GOYA, and 75% (95% CI: 70–79%) in the Pola-R-CHP arm of POLARIX. A limitation of this study was the comparison of the statistical models only in the PFS KM curves, since it was not possible to determine which statistical method was more appropriate to extrapolate the overall survival KM curves. Within this analysis, the mixture-cure model provided the best prediction of long-term outcomes from the primary PFS analysis of the POLARIX study.
Additional file 1 of Comparative effectiveness of multiple different treatment regimens for nonalcoholic fatty liver disease with type 2 diabetes mellitus: a systematic review and Bayesian network meta-analysis of randomised controlled trials
Creators: name: Deng, Manjun
name: Wen, Yonghao
name: Yan, JingXin
name: Fan, Yichen
name: Wang, Zhixin
name: Zhang, Ruixia
name: Ren, Li
name: Ba, Yinggui
name: Wang, Haijiu
name: Lu, Qian
name: Fan, Haining
Publisher: name: figshare
Year: 2023
Subjects: Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer
Science Policy

description: Additional file 1: Table S1. PRISMA 2020 Checklist. Table S2. Index and keyword terms used in the databases. Table S3. Lists of clinical trial registries and specialised journals. Table S4. Eligibility criteria. Table S5. Specific meaning of certainty in effect estimates. Table S6. List of excluded studies. Table S7. Certainty of evidence for direct, indirect and network estimates. Table S8. Adverse events of the interventions. Fig. S1. Quality assessment of the included studies and risk of bias summary for RCTs and risk of bias graph for RCTs. Individual risk of bias and overall risk of bias for each included study are visualised in green yellow and red representing low risk of bias unclear risk of bias and high risk of bias, respectively. Fig. S2. SUCRA ranking plot of intervention. (A) Liver fat content; (B) HbA1c; (C) BMI; (D) Waist circumference; (E) Insulin resistance; (F) ALT; (G) VATA; (H)SATA. The ranking plot represents the cumulative probability of being the best intervention, second and third. x-axis shows the relative rankings and y-axis shows the cumulative probability of each ranking. the larger the SUCRA, the higher it is ranked. Fig. S3. League matrix table of important but not crucial outcomes. (A) Insulin resistance; (B) ALT; (C) VATA; (D) SATA. Effect sizes where statistical differences exist are bolded, and the color of each cell indicates the certainty in effect estimates. Fig. S4. Funnel plots and Egger’s test. (A) HbA1c; (B) BMI; (C) Waist circumference; (D) Insulin resistance; (E) ALT. Fig. S5. Forest plot for inconsistency testing. (A) HbA1c; (B) Waist circumference; (C) BMI; (D) Insulin resistance; (E) ALT.
Transport in Superfluid Mixtures
Creators: name: Geracie, Michael
Publisher: name: arXiv
Year: 2016
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: Superconductivity (cond-mat.supr-con)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a general method for constructing effective field theories for non-relativistic superfluids, generalizing the previous approaches of Greiter, Witten, and Wilczek, and Son and Wingate to the case of several superfluids in solution. We investigate transport in mixtures with broken parity and find a parity odd "Hall drag" in the presence of independent motion as well as a pinning of mass, charge, and energy to sites of nonzero relative velocity. Both effects have a simple geometric interpretation in terms of the signed volumes and directed areas of various sub-complexes of a "velocity polyhedron": the convex hull formed by the endpoints of the velocity vectors of a superfluid mixture. We also provide a simple quasi-one-dimensional model that exhibits non-zero Hall drag.
description: 17 pages, 3 figures
Kinematics of z≥6 galaxies from [CII] line emission
Creators: name: Kohandel, Mahsa
Publisher: name: Zenodo
Year: 2020

description: We study the kinematical properties of galaxies in the Epoch of Reionization (redshift z> 6) via the [CII] line emission. The line profile provides information on the kinematics as well as structural properties such as the presence of a disk and satellites. To understand how these information are encoded in the line profile, we have first developed analytical models from which we identify disk inclination and gas turbulent motions as the key parameters affecting the emission line profile. To gain further insights, we use "Althaea", a high-resolution (30 pc) simulated prototypical Lyman Break Galaxy, in a cosmological environment. At z = 6-7 Althaea shows a disk structure with radius ~0.5 kpc. Its evolution presents three main evolutionary stages: I) Spiral Disk, II) Disturbed Disk, and III) Merger. By comparing the [CII] spectral profiles in these stages with the analytical galaxy model, we identified the spectral signatures of spiral arms, outflowing gas, and merger events in both face-on and edge-on views of Althaea. Comparing the extremely structured synthetic spectra to the observed galaxies, we find that Althaea in low inclinations has a similar FWHM to the observed galaxies (~ 180 km/s). We generalize the form of dynamical mass function vs. FWHM of the [CII] line for various structure of a galaxy. By knowing the exact inclination of the galaxy, this function has the lowest errors in estimating the galaxy mass while assuming a fixd inclination can increase this error to a factor of ~4. A Tully-Fisher like relation L_[CII] proportional to FWHM^1.8 is found for the observed high-z galaxies. We derive the general form of such relation and find that the value of the empirical fit is consistent with the theoretical guess. In this relation, we see a bias in non detection of lines with large FWHM and low luminosity(higher inclinations of small galaxies). By re-binning Althaea's spectra with channel width < 300 km/s, we clarified that edge-on views are more difficult to detect, suggesting this situation might be the cause of some of the non-detections in [CII] reported for the high-z observations.
Unconventional minimal subtraction and Bogoliubov-Parasyuk-Hepp-Zimmermann: massive scalar theory and critical exponents
Creators: name: Carvalho, Paulo R. S.
name: Leite, Marcelo M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We introduce a simpler although unconventional minimal subtraction renormalization procedure in the case of a massive scalar $λϕ^{4}$ theory in Euclidean space using dimensional regularization. We show that this method is very similar to its counterpart in massless field theory. In particular, the choice of using the bare mass at higher perturbative order instead of employing its tree-level counterpart eliminates all tadpole insertions at that order. As an application, we compute diagrammatically the critical exponents $η$ and $ν$ at least up to two loops. We perform an explicit comparison with the Bogoliubov-Parasyuk-Hepp-Zimmermann ($BPHZ$) method at the same loop order, show that the proposed method requires fewer diagrams and establish a connection between the two approaches.
description: Latex2e, 38 pages, 27 figures; matches published version with the Erratum included in the content of the text, one typo fixed in Eq. (44)
Evaluation of health economic impact of initial diagnostic modality selection for colorectal cancer liver metastases in suspected patients in China, Japan and the USA
Creators: name: Blankenburg, Michael
name: Elhamamy, Mostafa
name: Zhang, Diana
name: Fujikawa, Naoto
name: Corbin, Alice
name: Jin, Guanyi
name: Harris, James
name: Knobloch, Gesine
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Cell Biology
Neuroscience
Information Systems not elsewhere classified
Cancer

description: To compare cost offsets and contributing factors (false-negative rates and confirmatory imaging requirements, potentially leading to longer waiting times for diagnosis) as well as long-term cost effectiveness associated with the diagnostic and treatment pathways for colorectal cancer liver metastases (CRCLM) in the US, Japan, and China according to initial imaging modality used. Gadoxetate disodium (ethoxylbenzyl-diethylenetriaminepentaacetic acid)-enhanced magnetic resonance imaging (EOB-MRI) was compared to multidetector computed tomography (MDCT), extracellular contrast media enhanced-MRI (ECCM-MRI) (the US and China only) and contrast-enhanced ultrasound (CEUS). Decision tree models were developed to simulate the clinical pathway, from first diagnostic test to initial treatment decision, based on local clinical guidelines and validated by experts. Input data were derived from the literature (up to 31st December 2020) as well as from interviews with local experts. A Markov model extension was built to evaluate the number of false-negative patients and associated costs, over a lifetime horizon. The decision-tree models showed that, increasing proportionate use of initial EOB-MRI resulted in a cost-offset per patient (excluding false-negative patients) in all countries (USD 201 for the US, JPY 6,284 for Japan and CNY 446 for China) driven by reductions in follow-on diagnostic procedures and unnecessary treatment. The use of EOB-MRI was also associated with a shorter average waiting time to a final diagnosis and treatment decision compared to MDCT, ECCM-MRI and CEUS. The Markov model showed that with an increase in EOB-MRI use, there are fewer false-negative diagnoses over a lifetime horizon. In all three countries, the incremental cost-effectivenes ratio (ICER) was below standard willingness-to-pay thresholds. The findings of these models demonstrate that use of EOB-MRI early in the diagnostic pathway for CRCLM results in short-term cost savings, as well as being cost effective in the long term.
MOESM4 of Global sequence diversity of the lactate dehydrogenase gene in Plasmodium falciparum
Creators: name: Phumin Simpalipan
name: Sittiporn Pattaradilokrat
name: Pongchai Harnyuttanakorn
Publisher: name: figshare
Year: 2018
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 4. Neighbour Joining tree of 61 allelic sequences of the gene encoding lactate dehydrogenase (ldh) from 12 Plasmodium parasite species. The sequences are named according to parasite species and allelic type. The first two letters indicate parasite species: Pf (Plasmodium falciparum), Pm (Plasmodium malariae), Po (Plasmodium ovale), Pv (Plasmodium vivax), Pp (Plasmodium praefalciparum), Pr (Plasmodium reichenowi), Pbi (Plasmodium billcollinsi), Pbl (Plasmodium blacklocki), Pa (Plasmodium alderi), Pg (Plasmodium gaboni), Pk (Plasmodium knowlesi) and Pc (Plasmodium cynomolgi). Species showed on the right hand site are labelled with color representing parasite host: Homo sapiens (blue), Gorilla gorilla (black), Pan troglodytes (green) and Macaca fascicularis (red). The tree was constructed using the aligned sequences of 768 nucleotides, corresponding to nucleotide position 52â 819 after P. falciparum strain 3D7. Bootstrap values are shown next to the nodes. Scale bar shows nucleotide substitution per site.
The Neferhotep stela, revisited: kingship, authority and legitimacy in the Abydos stela of Neferhotep I
Creators: name: Neale, Helen
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Against the backdrop of the politically tumultuous Thirteenth Dynasty, the reign of Neferhotep I stands out for its length and stability. This stela of Neferhotep gives rare insight into the construction of royal authority and legitimacy, in a time where Egyptian kingship underwent extensive change. Ostensibly, this stela recorded the refashioning of the cult statue of Osiris, the form of which was based upon the king’s own research in the temple archives, as well as his personal participation in the associated festival of Osiris in Abydos. Yet, as an example of the Königsnovelle text type, this inscription also served to demonstrate the singular qualities of the king, his power to act, and his special relationship with the gods. The stela itself has been lost to history, and so for many years, the scholarship of it was hindered by the poor quality of its only drawn record. In light of the publication of a much improved hieroglyphic transcription by Helck, this thesis presents a new philological commentary of this inscription in its entirety, accompanied by a discussion of the ideology of kingship as conveyed in the text. In a time of great change, Neferhotep I drew upon the established religious motifs of Egyptian kingship in order to legitimise his reign and display his authority as king of Egypt.
title: Umbo de bouclier (Inv. 2014.34.1009.6) – Oppidum de Bibracte
Creators: name: Bibracte
Publisher: name: Conservatoire National des Données 3D (CND3D)
Year: 2024
Subjects: subject: armement (guerrier)

description: Les boucliers gaulois et romains diffèrent assez peu. De forme ovale et constitués d une mince planche de bois doublée de peau  leurs différentes parties sont maintenues par une légère coque métallique qui protège également la main  appelée umbo.
Comparison of statistical methods for extrapolating survival in previously untreated diffuse large B-cell lymphoma: results based on the POLARIX Study
Creators: name: Ho, Rodrigo S.
name: Launonen, Aino
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The ongoing Phase III randomized POLARIX study (GO39942; NCT03274492) demonstrated significantly improved progression-free survival (PFS) with polatuzumab vedotin plus rituximab, cyclophosphamide, doxorubicin and prednisone (Pola-R-CHP) versus rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with previously untreated diffuse large B-cell lymphoma (DLBCL). We compared statistical methodologies to extrapolate long-term PFS data from POLARIX. This analysis explored four different approaches to extrapolate the POLARIX data: standard parametric survival, mixture-cure, landmark, and spline models. The resulting extrapolation curves were validated via comparison with the corresponding Kaplan–Meier (KM) curves from POLARIX and the POLARIX-like population of the Phase III GOYA study (NCT01287741; R-CHOP arm). The R-CHOP PFS KM curve from the GOYA validation set was well aligned with the POLARIX KM curve. As we anticipated that PFS in POLARIX would evolve similarly to that of GOYA, the data from GOYA were used to externally validate the extrapolated modelling results. While all four statistical methods were able to fit the data to the POLARIX KM curve, the mixture-cure model was the most accurate in predicting long-term PFS in the GOYA external validation set. In the mixture-cure model, generalized gamma distribution estimated 64% (95% confidence intervals [CI]: 56%–71%) of patients to have long-term remission in the R-CHOP arm of POLARIX and GOYA, and 75% (95% CI: 70%–79%) in the Pola-R-CHP arm of POLARIX. A limitation of this study was the comparison of the statistical models only in the PFS KM curves, since it was not possible to determine which statistical method was more appropriate to extrapolate the overall survival KM curves. Within this analysis, the mixture-cure model provided the best prediction of long-term outcomes from the primary PFS analysis of the POLARIX study.
Additional file 1 of Development of an efficient protein expression system in the thermophilic fungus Myceliophthora thermophila
Creators: name: Li, Jinyang
name: Wang, Yidi
name: Yang, Kun
name: Wang, Xiaolu
name: Wang, Yuan
name: Zhang, Honglian
name: Huang, Huoqing
name: Su, Xiaoyun
name: Yao, Bin
name: Luo, Huiying
name: Qin, Xing
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Astronomical and Space Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Supplementary Material 1
How do pre-service teachers engage students in learning during professional experience?
Creators: name: Nicoll, Sandy
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Across the initial teacher education (ITE) literature, professional experience programs (PEP) are recognised as a key component of pre-service teachers’ education (Le Cornu, 2016; Zeichner, 2010). There is limited research on pre-service teachers’ (PSTs) experiences of participating in professional experience programs and an area that is least understood is how they engage primary school students in learning. Set against these gaps in the literature this narrative inquiry explored the experiences of PSTs during their professional experience placements in primary schools. I was interested in how PSTs were engaging their students in learning. The research focused on a small group of PSTs who completed their professional experience placements in primary schools within New South Wales in Australia. The study is a narrative inquiry into the experiences of these pre-service teachers and how they inquired into the way they engaged their students in learning during their day-to-day teaching. In the study I was positioned as a researcher and a teacher educator who worked with the pre-service teachers through their coursework. Field texts (data) for this study included focus groups, one-on-one conversations and questionnaires. Narrative accounts presented as portraits were composed from the data for each of the six PSTs. These portraits were then analysed further and I identified four emergent threads across the portraits: the connection/disconnection between theory and practice; the importance of relationships with key people who taught the pre-service teachers about engagement; the power of reflection on experience in the context of classroom practice; and how the pre-service teachers’ professional identities were shaped through each of these threads. My research revealed that, for these preservice teachers, Dewey’s (1938) concept of experience, engendered through narratives of critical events during professional experience, was a powerful influence on learning. The thesis highlights that an approach to pre-service teachers’ professional experience that is inquiry focused and grounded in the day-to-day practices of teaching may contribute to valuable opportunities for learning how to engage primary school students. These findings have implications for the design of professional experience programs in ITE.
SLOCC classification of n qubits invoking the proportional relationships for spectrums and for standard Jordan normal forms
Creators: name: Li, Dafa
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the proportional relationships for spectrums and for SJNFs (Standard Jordan Normal Forms) of the matrices constructed from coefficient matrices of two SLOCC (stochastic local operations and classical communication) equivalent states of $n$ qubits. Invoking the proportional relationships for spectrums and for SJNFs, pure states of $n$ ($\geq 4$) qubits are partitioned into 12 groups and 34 families under SLOCC, respectively. Specially, it is true for four qubits.
description: 5 pages,no figure, submit to PRL
Atezolizumab treatment of tumors with high tumor mutational burden from MyPathway, a multicenter, open-label, phase IIa multiple basket study.
Creators: name: Friedman, Claire F
name: Hainsworth, John D
name: Kurzrock, Razelle
name: Spigel, David R
name: Burris, Howard A
name: Sweeney, Christopher J
name: Meric-Bernstam, Funda
name: Wang, Yong
name: Levy, Jonathan
name: Grindheim, Jessica
name: Shames, David S
name: Schulze, Katja
name: Patel, Arisha
name: Swanton, Charles
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: classificationCode: Tumour Biology
subject: Tumour Biology
classificationCode: Signalling & Oncogenes
subject: Signalling & Oncogenes
classificationCode: Genetics & Genomics
subject: Genetics & Genomics
classificationCode: Genome Integrity & Repair
subject: Genome Integrity & Repair
classificationCode: Human Biology & Physiology
subject: Human Biology & Physiology
classificationCode: Chemical Biology & High Throughput
subject: Chemical Biology & High Throughput
classificationCode: Ecology,Evolution & Ethology
subject: Ecology,Evolution & Ethology
classificationCode: Computational & Systems Biology
subject: Computational & Systems Biology

description: High tumor mutational burden (TMB-H) correlates with improved immunotherapy response. We assessed atezolizumab 1200-mg every 3 weeks for TMB-H tumors from MyPathway (NCT02091141), a phase 2a multi-basket study. One hundred twenty-one patients had advanced solid tumors with TMB {greater than or equal to}10 mut/Mb by any CLIA assay. The pre-planned primary endpoint was objective response rate (ORR) in patients with TMB {greater than or equal to}16 mut/Mb tumors by FoundationOne TMB testing (F1[CDx]). Patients with F1(CDx) TMB {greater than or equal to}10 and <16 mut/Mb were also evaluated. Ninety patients with 19 tumor types and F1(CDx) TMB {greater than or equal to}10 mut/Mb were efficacy-evaluable. In 42 patients with F1(CDx) TMB {greater than or equal to}16 mut/Mb, confirmed ORR was 38.1% (16/42, 95% CI 23.6-54.4) and disease control rate was 61.9% (26/42, 95% CI 45.6-76.4), versus 2.1% (1/48, 95% CI 0.1-11.1) and 22.9% (11/48, 95% CI 12.0-37.3) for 48 patients with TMB {greater than or equal to}10 and <16 mut/Mb. Responses were observed in nine different tumor types (47% [9/19]).
$\mathbb{Z}_3$ parafermionic zero modes without Andreev backscattering from the $2/3$ fractional quantum Hall state
Creators: name: Alavirad, Yahya
name: Clarke, David
name: Nag, Amit
name: Sau, Jay D.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Parafermionic zero modes are a novel set of excitations displaying non-Abelian statistics somewhat richer than that of Majorana modes. These modes are predicted to occur when nearby fractional quantum Hall edge states are gapped by an interposed superconductor. Despite substantial experimental progress, we argue that the necessary crossed Andreev reflection in this arrangement is a challenging milestone to reach. We propose a superconducting quantum dot array structure on a fractional quantum Hall edge that can lead to parafermionic zero modes from coherent superconducting forward scattering on a quantum Hall edge. Such coherent forward scattering has already been demonstrated in recent experiments. We show that for a spin-singlet superconductor interacting with loops of spin unpolarized $2/3$ fractional quantum edge, even an array size of order ten should allow one to systematically tune into a parafermionic degeneracy.
description: 4 pages, 3 figures, 5 pages of supplementary material
Additional file 3: of A systematic review of chronic disease management interventions in primary care
Creators: name: Reynolds, Rebecca
name: Dennis, Sarah
name: Hasan, Iqbal
name: Slewa, Jan
name: Chen, Winnie
name: Tian, David
name: Sangeetha Bobba
name: Zwar, Nicholas
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Quality assessment template. (DOCX 29Â kb)
To wait, or too late? Modeling the effects of delayed ofatumumab treatment in relapsing-remitting multiple sclerosis
Creators: name: Montgomery, Stephen Maxwell
name: Green, Luke
name: Karoui, Hajer
name: Nicholas, Richard
name: Loh, Jaclyn
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Pharmacology
Biotechnology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified

description: Several disease-modifying treatments (DMTs) for relapsing-remitting multiple sclerosis (RRMS) reduce relapse rates and slow disease progression. RRMS DMTs have varying efficacy and administration routes; DMTs prescribed first may not be the most effective on relapses or disease progression. Here, we aimed to quantify the benefit of initiating ofatumumab, a high-efficacy DMT, earlier in the treatment pathway. Aggregate data from a real-world cohort of patients with RRMS, who were eligible for dimethyl fumarate (DMF) or ofatumumab treatment within the UK National Health Service (N = 615), were used to produce a simulated patient cohort. The cohort was tracked through a discrete event simulation (DES) model, based on the Expanded Disability Status Scale (EDSS), with a lifetime time horizon. Outcomes assessed were: mean number of relapses, time to wheelchair (EDSS ≥7), and time to death. Two modeling approaches were used. The first compared outcomes between two treatment sequences (base case: ofatumumab to natalizumab versus DMF to ofatumumab). The second incorporated a time-specific delay of 1–5 years for switching from DMF to ofatumumab; the difference in outcomes as a function of increasing delay to ofatumumab are reported. Compared with delayed ofatumumab, fewer relapses and increased time to wheelchair were predicted for earlier ofatumumab in the treatment-sequence approach (mean relapses over the lifetime time horizon: 8.63 versus 9.00; time to wheelchair: 17.55 versus 16.60 years). Time to death was similar for both sequences. At Year 10, a numerically greater proportion of patients receiving earlier ofatumumab had mild disease (EDSS 0–3: 44.12% versus 40.06%). Greater differences, reflecting poorer outcomes, were predicted for relapses and time to wheelchair with increasing delays to ofatumumab treatment. The DES model provided a means by which the magnitude of benefit associated with earlier ofatumumab initiation could be quantified; fewer relapses and a prolonged time to wheelchair were predicted.
Guided Lock of a Suspended Optical Cavity Enhanced by a Higher Order Extrapolation
Creators: name: Izumi, Kiwamu
name: Arai, Koji
name: Tatsumi, Daisuke
name: Takahashi, Ryutaro
name: Miyakawa, Osamu
name: Fujimoto, Masa-Katsu
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Lock acquisition of a suspended optical cavity can be a highly stochastic process and is therefore nontrivial. Guided lock is a method to make lock acquisition less stochastic by decelerating the motion of the cavity length based on an extrapolation of the motion from an instantaneous velocity measurement. We propose an improved scheme which is less susceptible to seismic disturbances by incorporating the acceleration as a higher order correction in the extrapolation. We implemented the new scheme in a 300-m suspended Fabry-Perot cavity and improved the success rate of lock acquisition by a factor of 30.
title: Umbo de bouclier (Inv. 2014.34.1009.6)
Creators: name: Fochesato, Andrea
name: Bavay, Laurent
name: Vitali, Daniele
name: Martin, Fanny
Publisher: name: Conservatoire National des Données 3D (CND3D)
Year: 2024
Subjects: subject: armement (guerrier)
subject: Artefact
subject: ACQUISITION

description: Modèle 3D
EUV and Magnetic Activities Associated with Type-I Solar Radio Bursts
Creators: name: Li, Chuanyang
name: Chen, Yao
name: Wang, Bing
name: Ruan, Guiping
name: Feng, Shiwei
name: Du, Guohui
name: Kong, Xiangliang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Type-I bursts (i.e. noise storms) are the earliest-known type of solar radio emission at the metre wavelength. They are believed to be excited by non-thermal energetic electrons accelerated in the corona. The underlying dynamic process and exact emission mechanism still remain unresolved. Here, with a combined analysis of extreme ultraviolet (EUV), radio and photospheric magnetic field data of unprecedented quality recorded during a type-I storm on 30 July 2011, we identify a good correlation between the radio bursts and the co-spatial EUV and magnetic activities. The EUV activities manifest themselves as three major brightening stripes above a region adjacent to a compact sunspot, while the magnetic field there presents multiple moving magnetic features (MMFs) with persistent coalescence or cancelation and a morphologically similar three-part distribution. We find that the type-I intensities are correlated with those of the EUV emissions at various wavelengths with a correlation coefficient of 0.7-0.8. In addition, in the region between the brightening EUV stripes and the radio sources there appear consistent dynamic motions with a series of bi-directional flows, suggesting ongoing small-scale reconnection there. Mainly based on the induced connection between the magnetic motion at the photosphere and the EUV and radio activities in the corona, we suggest that the observed type-I noise storms and the EUV brightening activities are the consequence of small-scale magnetic reconnection driven by MMFs. This is in support of the original proposal made by Bentely et al. (Solar Phys. 193, 227, 2000).
MOESM1 of Genome-wide diversity and runs of homozygosity in the “Braque Français, type Pyrénées” dog breed
Creators: name: Mastrangelo, Salvatore
name: Biscarini, Filippo
name: Auzino, Barbara
name: Ragatzu, Marco
name: Spaterna, Andrea
name: Ciampolini, Roberta
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Marine Biology

description: Additional file 1. Plink command lines. File with the Plink command lines used to: (i) edite the SNP data; (ii) select unlinked SNP loci for the estimation of $$N_e$$ N e ; (iii) detect runs of homozygosity (ROH).
Anorexia nervosa and body representation
Creators: name: Gadsby, Stephen
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Research has shown that anorexia nervosa patients represent their bodies in a distorted manner, as larger than reality. This distortion is seen in three kinds of body representations: the body percept (the mental image we have of our bodies), the body schema (used for motor control and simulation) and a representation I call the tactile form (used for certain kinds of tactile perception). In this thesis I fit this evidence into a broader framework for understanding how the spatial content of the body is tracked and stored. I do so by first discussing O’Shaughnessy’s (1980) long-term body image hypothesis. This hypothesis posits a representation that tracks changes in the spatial content of the body and supplies this content to other body representations. I argue that a similar kind of body representation might exist, supplying spatial content to the body percept, body schema and tactile form. I then explain the evidence of distortion in patients’ body representations by suggesting it arises in in this long-term representation. I also discuss what role this distortion plays in maintaining the disease. I suggest that body percept and body schema distortion causes patients to have oversized experiences of their bodies. Along with socio-cultural influences, these oversized experiences help ground patients’ propositional attitudes about their own body size. These propositional attitudes, in turn, motivate harmful dieting behaviour. As such, I show that distorted body representations play an important role in maintaining the disease.
REVIEW - ALMA Brings Molecular Gas in Galaxies Into Focus
Creators: name: Leroy, Adam
Publisher: name: Zenodo
Year: 2020

description: Over its first few years of operation, ALMA has dramatically sharpened our view of cold gas in galaxies. I will review highlights from these first few years. These include resolving cold gas disks and outflows from centers of active galaxies, discovering forming star clusters in dwarf and starburst galaxies, and directly imaging the dense, star-forming gas in other galaxies. I will also give an overview of ALMA's first Large Program targeting nearby galaxies. PHANGS ALMA is carrying out the first high completeness, wide area survey of individual molecular clouds across the whole nearby galaxy population. Using CO 2-1 emission, this survey traces the structure and kinematics of gas at ~ 100 pc resolution across more than 80 nearby star forming galaxies. These observations reveal a highly structured medium in which the distribution and properties of cold gas clouds are closely coupled to the host galaxy and galactic environment. When the cold gas seen by ALMA is contrasted with signatures of high mass star formation, these same observations show a violent cycle of cloud collapse and feedback. Based on what ALMA has done so far, I will also call out some of the major questions for the next five years.
Feynman-Kac Formulas for Regime-Switching Jump Diffusions and their Applications
Creators: name: Zhu, Chao
name: Yin, George
name: Baran, Nicholas A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: This work develops Feynman-Kac formulas for a class of regime-switching jump diffusion processes, in which the jump part is driven by a Poisson random measure associated to a general Lévy process and the switching part depends on the jump diffusion processes. Under broad conditions, the connections of such stochastic processes and the corresponding partial integro-differential equations are established. Related initial, terminal, and boundary value problems are also treated. Moreover, based on weak convergence of probability measures, it is demonstrated that a sequence of random variables related to the regime-switching jump diffusion process converges in distribution to the arcsine law.
description: Stochastics, 2015
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 0456
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0456, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0456, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Additional file 1 of Detailed statistical analysis plan for a secondary Bayesian analysis of the SafeBoosC-III trial: a multinational, randomised clinical trial assessing treatment guided by cerebral oximetry monitoring versus usual care in extremely preterm infants
Creators: name: Olsen, Markus Harboe
name: Hansen, Mathias Lühr
name: Lange, Theis
name: Gluud, Christian
name: Thabane, Lehana
name: Greisen, Gorm
name: Jakobsen, Janus Christian
Publisher: name: figshare
Year: 2023
Subjects: subject: Statistics
subject: FOS: Mathematics

description: Additional file 1.
Young stellar populations in type II quasars: timing the onset of star formation and nuclear activity
Creators: name: Bessiere, Patricia S
name: Tadhunter, Clive N
name: Almeida, Cristina Ramos
name: Villar-Martin, Montserrat
name: Cabrera-Lavers, Antonio
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Despite the emerging morphological evidence that luminous quasar-like AGN are triggered in galaxy mergers, the natures of the triggering mergers and the order of events in the triggering sequence remain uncertain. In this work, we present a detailed study of the stellar populations of the host galaxies of 21 type II quasars, with the aim of understanding the sequence of events between the onset of the merger, the triggering of the associated starburst and the initiation of the quasar activity. To this end, we model high quality, wide spectral coverage, intermediate resolution optical spectra of the type II quasars. We find that of the 21 objects, the higher-order Balmer absorption lines, characteristic of young stellar populations (YSP) , are directly detected in ~62% of the sample. We also fit these spectra using a number of combinations of stellar and/or power-law components, representative of viable formation histories, as well as including the possibility of scattered AGN light. We find that 90 % of the type II quasar host galaxies require the inclusion of a YSP to adequately model their spectra, whilst 71 % of the sample require the inclusion of a YSP with age < 100 Myr. Since the ages of the YSP in most type II quasar host galaxies are comparable with the expected lifetimes of the AGN activity, these results provide strong evidence that the quasars are triggered close to the peaks of the merger-induced starbursts.
description: Accepted for publication in MNRAS, 22 pages with an additional 11 page appendix, 31 Figures
The myMoves Program: development of a remote self-management program to increase physical activity after acquired brain injury
Creators: name: Jones, Taryn M.
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Acquired brain injury (ABI) is a significant cause of disability globally, with common causes being stroke and trauma. Individuals living with ABI often display high levels of physical inactivity and sedentary behaviour, which increases their risk of morbidity and mortality. However, many adults with ABI experience barriers to participation in effective physical activity interventions. Remotely delivered self-management programs focussed on teaching individuals how to improve and maintain their physical activity levels have the potential to improve the overall health of adults with ABI. The development of a complex and multifaceted health intervention, such as self-management program to increase physical activity, requires a scholarly and systematic approach to the development process, underpinned with a sound theoretical basis. The work presented in this Thesis demonstrates this rigorous development process, using an Intervention Mapping framework, to develop an innovative remotely delivered self-management program focussed specifically on assisting individuals living in the Australian community to increase their physical activity. The development process commenced with a comprehensive needs assessment; including a systematic review of the literature on the efficacy of self-management programs to increase physical activity after ABI (Study I), and a survey of potential participants regarding barriers to physical activity and interest in a program of this nature (Study II). The detailed developmental process is outlined (Study III), and resulted in a comprehensive self-management program, the myMoves Program. Initial testing of this program has been conducted (Study IV) demonstrating that it is both feasible to deliver, and highly acceptable to participants. Testing also informed an iterative review of the program (Study V) to conclude the developmental process and inform future testing of efficacy. In essence, the work presented in this Thesis has demonstrated the successful development of a remotely delivered self-management program focused at increasing physical activity for individuals living in the community with ABI.
title: ADCO, Cartulaire de Fontenay, premier fragment (XIIIe siècle), Cart. 201 (15 H 9), 175 folios, f. 003r
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Fontenay, premier fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), 175 folios. Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Fontenay, premier fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), 175 folios, f. 003r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb119679755
description: Provenance: https://www.geonames.org/7874015
description: Provenance: http://www.idref.fr/027691802/id
description: Provenance: abbaye de Fontenay
description: Provenance: http://www.wikidata.org/entity/Q464918
MOESM3 of In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate
Creators: name: Cravo, Pedro
name: Machado, Renato
name: Leite, Juliana
name: Taizy Leda
name: Rossarin Suwanarusk
name: Najara Bittencourt
name: Letusa Albrecht
name: Judice, Carla
name: Lopes, Stefanie
name: Lacerda, Marcus
name: Ferreira, Marcelo
name: Soares, Irene
name: Goh, Yun
name: Bargieri, Daniel
name: Nosten, François
name: Russell, Bruce
name: Rénia, Laurent
name: Costa, Fabio
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 3. Predicted Plasmodium yoelii B-cell epitopes within the putative MAEBL antigen. (Epitopes were generated using BCPRED software. Resulting epitopes were subsequently screened for predicted antigenicity using the VaxiJen resource. BLAST was used to interrogate potential homology between the selected P. yoelii epitopes and the P. falciparum and P. vivax MAEBL antigens).