cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ESG ratings and credit ratings
Creators: name: Γαλεράκης-Στεργίου, Βάιος
name: Galerakis-Stergiou, Vaios
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2022
Subjects: subject: ESG ratings
subject: Credit ratings
subject: Corporate sustainability
subject: ESG (Environmental, Social, Governance)

description: Σε αυτή τη μελέτη εξετάζω τη σχέση μεταξύ της περιβαλλοντικής, κοινωνικής και διακυβερνητικής (ESG) επίδοσης και της πιστοληπτικής ικανότητας των επιχειρήσεων. Ακόμη, διερευνώ ποιος από τους πυλώνες της επίδοσης ESG συνεισφέρει σε αυτή τη σχέση. Η μελέτη ξεκινάει με μία ανασκόπηση των προβλημάτων της ασσυμετρίας πληροφόρησης και των βαθμολογήσεων που χρησιμοποιούν οι οικονομικοί παράγοντες για να τα αντιμετωπίσουν. Σημειώνω τους προσδιοριστικούς παράγοντες των βαθμών πιστοληπτικής ικανότητας των εταιρειών και τονίζω της αδυναμίες στον ορισμό και στον τρόπο μέτρησης της επίδοσης ESG. Η παρουσίαση της σχέσης μεταξύ της επίδοσης ESG και της χρηματοοικονομικής επίδοσης της εταιρείας ολοκληρώνει την επισκόπηση της βιβλιογραφίας. Με χρήση ενός δείγματος 600 εταιρειών για την περίοδο από το 2002 έως το 2020, βρίσκω μίας θετική σχέση μεταξύ των ESG βαθμολογήσεων και των βαθμών πιστοληπτικής ικανότητας των εταιρειών, με μόνο τον πυλώνας της κοινωνικής επίδοσης να συνεισφέρει στη σχέση αυτή.
Megapinosomes and homologous structures in hematopoietic cells
Creators: name: Bauer, Andrea
name: Frascaroli, Giada
name: Walther, Paul
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: M macrophages
subject: Megapinosomes
subject: High-pressure freezing
subject: STEM tomography
subject: DDC 570 / Life sciences
subject: Macrophages
subject: Megakaryocytes
subject: Blood platelets
subject: Electron microscopy
subject: Megakaryozyt
subject: Thrombozyt

description: Megapinosomes are endocytic organelles found in human macrophage colony-stimulating factor (M-CSF) monocyte-derived M macrophages. They are large (several microns) and have a complex internal structure that is connected with the cytosol and consists of interconnected knots and concave bridges with sizes in the range of 100 nm. We called this structure trabecular meshwork. The luminal part of the megapinosome can be connected with luminal tubules and cisterns that form the megapinosome complex. The structures are especially well visible in scanning electron tomography when macrophages are prepared by high-pressure freezing and freeze substitution. Our research received a new impulse after studying the literature on hematopoietic cells, where very similar, most likely homologous, structures have been published in peritoneal macrophages as well as in megakaryocytes and blood platelets. In platelets, they serve as membrane storage that is used for structural changes of platelets during activation.
Innovative medizinische Betreuungskonzepte für Jugendliche mit extremer Adipositas
Creators: name: Wabitsch, Martin
name: V. Schnurbein, Julia
name: Vollbach, Heike
name: Lennerz, Belinda
name: Weyhreter, Helmut
name: Wiegand, Susanna
name: Kiess, Wieland
name: Hebebrand, Johannes
name: Brandt, Stephanie
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Körpergewichtsregulation
subject: Adipositaschirurgie
subject: Jobcenter
subject: Wohngruppe
subject: Stigmatisierung
subject: Body weight regulation
subject: Bariatric surgery
subject: Job center
subject: Living unit
subject: Stigmatisation
subject: DDC 610 / Medicine & health

description: Zusammenfassung Für Jugendliche mit extremer Adipositas gibt es bislang kein überzeugendes, wissenschaftsbasiertes Behandlungs- und Betreuungskonzept, weder in Deutschland noch in anderen Ländern. Die betroffenen Jugendlichen haben ein erhöhtes Risiko für zahlreiche somatische Folgeerkrankungen wie Diabetes mellitus Typ 2, orthopädische Störungen und das Schlafapnoesyndrom. Auch psychische Störungen wie Depression und Angststörungen, soziale Phobien und selbstverletzendes Verhalten können sich aufgrund der funktionellen Beeinträchtigungen und der Stigmatisierung entwickeln. Soziale Isolation einschließlich Schulvermeidung und Arbeitslosigkeit können die Folge sein. Trotz dieser negativen Auswirkungen der extremen Adipositas im Jugendalter sind diese Jugendlichen medizinisch schwer zu erreichen und zu behandeln. Nur ein kleiner Prozentsatz der Patienten sucht aktiv nach einer Behandlung. In Kenntnis dieser Schwierigkeiten wurde von 2012–2019 die vom Bundesministerium für Bildung und Forschung (BMBF) geförderte JA-Studie (Jugendliche mit extremer Adipositas) durchgeführt mit dem Ziel, die Versorgungskonzepte für diese vernachlässigte Gruppe von Jugendlichen zu verbessern. In unserem Beitrag zeigen wir mögliche Versorgungswege auf. Diese bestehen in der Begleitung der Jugendlichen und der Behandlung von Komorbiditäten, einer nachhaltigen Lebensstilintervention in einem geschützten Umfeld sowie einer Therapie zur Gewichtsreduktion durch Adipositaschirurgie. Übergeordnete Ziele für die Patienten bestehen dabei in einer Steigerung des Selbstwertgefühls, in der frühzeitigen Diagnose und Behandlung von Folgeerkrankungen und in einer Integration in den Ausbildungs- bzw. Arbeitsmarkt.
NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance
Creators: name: Arinrad, Sahab
name: Wilke, Justus B. H.
name: Seelbach, Anna
name: Doeren, José
name: Hindermann, Martin
name: Butt, Umer Javed
name: Steixner-Kumar, Agnes A.
name: Spieth, Lena
name: Ronnenberg, Anja
name: Pan, Hong
name: Berghoff, Stefan A.
name: Hollmann, Michael
name: Lühder, Fred
name: Nave, Klaus-Armin
name: Bechter, Karl
name: Ehrenreich, Hannelore
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: ASPARTATE RECEPTOR ANTIBODIES
subject: SERUM AUTOANTIBODIES
subject: CASE DEFINITIONS
subject: DDC 150 / Psychology
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Psychiatric disorders
subject: Prefrontal cortex
subject: Brain
subject: Memory
subject: Mice
subject: Schizophrenia
subject: Myelin
subject: Gehirn
subject: Gedächtnis
subject: Maus
subject: Schizophrenie

description: Abstract Encephalitis has an estimated prevalence of ≤0.01%. Even with extensive diagnostic work-up, an infectious etiology is identified or suspected in <50% of cases, suggesting a role for etiologically unclear, noninfectious processes. Mild encephalitis runs frequently unnoticed, despite slight neuroinflammation detectable postmortem in many neuropsychiatric illnesses. A widely unexplored field in humans, though clearly documented in rodents, is genetic brain inflammation, particularly that associated with myelin abnormalities, inducing primary white matter encephalitis. We hypothesized that “autoimmune encephalitides” may result from any brain inflammation concurring with the presence of brain antigen-directed autoantibodies, e.g., against N-methyl-D-aspartate-receptor NR1 (NMDAR1-AB), which are not causal of, but may considerably shape the encephalitis phenotype. We therefore immunized young female Cnp−/− mice lacking the structural myelin protein 2′-3′-cyclic nucleotide 3′-phosphodiesterase (Cnp) with a “cocktail” of NMDAR1 peptides. Cnp−/− mice exhibit early low-grade inflammation of white matter tracts and blood–brain barrier disruption. Our novel mental-time-travel test disclosed that Cnp−/− mice are compromised in what–where–when orientation, but this episodic memory readout was not further deteriorated by NMDAR1-AB. In contrast, comparing wild-type and Cnp−/− mice without/with NMDAR1-AB regarding hippocampal learning/memory and motor balance/coordination revealed distinct stair patterns of behavioral pathology. To elucidate a potential contribution of oligodendroglial NMDAR downregulation to NMDAR1-AB effects, we generated conditional NR1 knockout mice. These mice displayed normal Morris water maze and mental-time-travel, but beam balance performance was similar to immunized Cnp−/−. Immunohistochemistry confirmed neuroinflammation/neurodegeneration in Cnp−/− mice, yet without add-on effect of NMDAR1-AB. To conclude, genetic brain inflammation may explain an encephalitic component underlying autoimmune conditions.
TropFishR: an R package for fisheries analysis with length-frequency data
Creators: name: Mildenberger, Tobias
name: Taylor, Marc
Publisher: name: figshare
Year: 2017
Subjects: subject: Marine Biology
subject: 60205 Marine and Estuarine Ecology (incl. Marine Ichthyology)
subject: FOS: Biological sciences
subject: 60207 Population Ecology

description: 1. The R package TropFishR is a new analysis toolbox compiling single-species stock assessment methods specifically designed for data-limited fisheries analysis using length-frequency data.2. It includes methods for (i) estimating biological stock characteristics such as growth and mortality parameters, (ii) exploring technical aspects of the fisheries (e.g. exploitation rate and selectivity characteristics), (iii) assessing size and composition of a fish stock by means of virtual population analysis (VPA), and (iv) assessing stock status with yield prediction and production models.3. This paper introduces the package and demonstrates the functionality of a selection of its core methods.4. TropFishR modernises traditional stock assessment methods by easing application and development and by combining it with advanced statistical approaches.
title: OFROM: interview avec unine15a28m
Creators: name: Delafontaine, François
name: Ehinger, Maude
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.93d2491l.v2#300c50861aaf3ba87e2164b3d5b229be713572ad
Supplementary Material for: Detecting Endometriosis in Adolescents: Why Not Start from Self-Report Screening Questionnaires for Adult Women
Creators: name: Geysenbergh, B.
name: Dancet E.A.F.
name: D'Hooghe, T.
Publisher: name: Karger Publishers
Year: 2016
Subjects: Medicine

description: Background: Endometriosis in adolescent girls is often diagnosed after a long delay. This diagnostic delay can be associated with more advanced stages of endometriosis and with a higher likelihood of fertility problems at a later age. Material and Methods: A systematic review of literature and quality assessment was performed in order to identify questionnaires that were developed to identify adult women with endometriosis. Based on these questionnaires, specific questions that had been reported to be predictive for endometriosis were selected and included in a newly composed questionnaire with the aim to identify adolescents at risk of developing endometriosis. Results: Based on the literature, we identified 5 questionnaires developed to identify adult women with endometriosis; this questionnaire contained 6 questions that had been reported to be predictive for adult endometriosis. These questions query age of menarche, cycle duration, dysmenorrhea, pain descriptors, dyschezia and urinary symptoms and were combined into a new self-report questionnaire aimed to identify adolescents at risk to develop endometriosis. Conclusion: We developed a self-report questionnaire aimed to identify adolescents at risk to develop endometriosis based on questions from self-report questionnaires that have been reported to identify adult women with endometriosis.
title: Οι τομείς παραγωγής στην Ελλάδα και η εργασιακή ικανοποίηση
title: Production sectors in Greece and work satisfaction
titleType: AlternativeTitle
Creators: name: Σεκλού, Σωτηρία
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2022
Subjects: Τομείς παραγωγής
Βασικές θεωρίες παρακίνησης
Εργασιακή ικανοποίηση
Παραγωγικοί συντελεστές
Εργασία
Ανθρώπινος παράγοντας
Παρακίνηση εργαζομένων

description: Η ικανοποίηση των αναγκών είναι η βασική επιδίωξη του κάθε ανθρώπου σε όλη του τη ζωή. Αυτή η ικανοποίηση υφίσταται μόνο με τη χρήση προϊόντων. Τα προϊόντα αυτά τα παράγουν κυρίως οι επιχειρήσεις οι οποίες ταξινομούνται σε τομείς και κλάδους ανάλογα με τα προϊόντα που παράγουν και προσφέρουν. Οι τομείς της παραγωγής είναι ο πρωτογενής, ο δευτερογενής και ο τριτογενής. Σκοπός: Η εν λόγω εργασία εστιάζει και παραθέτει τους παραπάνω τομείς παραγωγής. Σκοπό έχει να γίνει κατανοητό τι περιλαμβάνουν αυτοί οι τομείς, ποια είναι η δομή τους και ποια η λειτουργία τους ενώ γίνεται αναφορά και της κατάστασης των τομέων αυτών στην ελληνική οικονομία. Επίσης σκοπός είναι η καταγραφή της ικανοποίησης των εργαζομένων και στους τρεις τομείς παραγωγής. Μεθοδολογία έρευνας: Η έρευνα με τη βοήθεια της βιβλιογραφίας αναλύει θεωρητικά τους τομείς παραγωγής και την επαγγελματική ικανοποίηση, και στη συνέχεια με τη χρήση ερωτηματολογίου ερευνά σε βάθος την κατάσταση των τομέων και της εργασιακής ικανοποίησης στην Ελλάδα. Συμπεράσματα: Η Ελλάδα πέρασε μια δεκαετή τουλάχιστον οικονομική κρίση και τα προβλήματα που δημιούργησε αυτή στους τομείς παραγωγής και στην οικονομία της χώρας γενικότερα είναι πολλά και δύσκολο να επιλυθούν. Όμως μόνο με μια ιδιαίτερη και συνεχή διαχείριση των εργαζομένων είναι πιθανό να αντιμετωπιστούν κάποιες από αυτές τις δυσκολίες και να προσαρμοστεί η οικονομία της χώρας στα νέα πια δεδομένα
Imposed dynamic irradiation to intensify photocatalytic reactions
Creators: name: Guba, Fabian
name: Gaulhofer, Florian
name: Ziegenbalg, Dirk
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Dynamic irradiation
subject: Intensification
subject: Reaction engineering
subject: Synchronizing time scales
subject: CFD
subject: DDC 540 / Chemistry & allied sciences
subject: Photocatalysis
subject: Fotokatalyse
subject: Intensivierung

description: Dynamic irradiation is a potent option to influence the interaction between photochemical reactions and mass transport to design high performant and efficient photochemical processes. To systematically investigate the impact of this parameter, the photocatalytic reduction of nitrobenzene was conducted as a test reaction. Dynamic irradiation was realized through provoked secondary flow patterns, multiple spatially distributed light emitting diodes (LEDs) and electrical pulsation of LEDs. A combined experimental and theoretical approach revealed significant potential to enhance photochemical processes. The reaction rate was accelerated by more than 70% and even more important the photonic efficiency was increased by more than a factor of 4. This renders imposed dynamic irradiation an innovative and powerful tool to intensify photoreactions on the avenue to large scale sustainable photochemical processes.
Improved reliability of automated ASPECTS evaluation using iterative model reconstruction from head CT scans
Creators: name: Löffler, Maximilian T.
name: Sollmann, Nico
name: Mönch, Sebastian
name: Friedrich, Benjamin
name: Zimmer, Claus
name: Baum, Thomas
name: Maegerlein, Christian
name: Kirschke, Jan S.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Cerebrovascular disease and stroke
subject: computer-assisted image analysis
subject: iterative image reconstruction
subject: middle cerebral artery infarction
subject: multidetector computed tomography
subject: DDC 610 / Medicine & health
subject: Cerebrovascular disorders
subject: Ischemic stroke
subject: Cerebral infarction
subject: Tomography, X-ray computed
subject: Image processing, Computer-assisted
subject: Thrombectomy
subject: Schlaganfall
subject: Hirngefäßkrankheit
subject: Computertomografie
subject: Thrombektomie

description: ABSTRACT BACKGROUND AND PURPOSE Iterative model reconstruction (IMR) has shown to improve computed tomography (CT) image quality compared to hybrid iterative reconstruction (HIR). Alberta Stroke Program Early CT Score (ASPECTS) assessment in early stroke is particularly dependent on high‐image quality. Purpose of this study was to investigate the reliability of ASPECTS assessed by humans and software based on HIR and IMR, respectively. METHODS Forty‐seven consecutive patients with acute anterior circulation large vessel occlusions (LVOs) and successful endovascular thrombectomy were included. ASPECTS was assessed by three neuroradiologists (one attending, two residents) and by automated software in noncontrast axial CT with HIR (iDose4; 5 mm) and IMR (5 and 0.9 mm). Two expert neuroradiologists determined consensus ASPECTS reading using all available image data including MRI. Agreement between four raters (three humans, one software) and consensus were compared using square‐weighted kappa (κ). RESULTS Human raters achieved moderate to almost perfect agreement (κ = .557‐.845) with consensus reading. The attending showed almost perfect agreement for 5 mm HIR (κHIR = .845), while residents had mostly substantial agreements without clear trends across reconstructions. Software had substantial to almost perfect agreement with consensus, increasing with IMR 5 and 0.9 mm slice thickness (κHIR = .751, κIMR = .777, and κIMR0.9 = .814). Agreements inversely declined for these reconstructions for the attending (κHIR = .845, κIMR = .763, and κIMR0.9 = .681). CONCLUSIONS Human and software rating showed good reliability of ASPECTS across different CT reconstructions. Human raters performed best with the reconstruction algorithms they had most experience with (HIR for the attending). Automated software benefits from higher resolution with better contrasts in IMR with 0.9 mm slice thickness.
TropFishR: an R package for fisheries analysis with length-frequency data
Creators: name: Mildenberger, Tobias
name: Taylor, Marc
Publisher: name: figshare
Year: 2016
Subjects: subject: Marine Biology
subject: 60205 Marine and Estuarine Ecology (incl. Marine Ichthyology)
subject: FOS: Biological sciences
subject: 60207 Population Ecology

description: 1. The R package TropFishR is a new analysis toolbox compiling traditional and advanced single-species stock assessment methods for the analysis of small-scale and data-poor fisheries.2. It includes functions for (i) estimating biological stock characteristics such as growth and mortality parameters, (ii) exploring technical aspects of the fisheries (e.g. exploitation rate and selectivity characteristics), (iii) assessing size and composition of a fish stock by means of Virtual population analysis (VPA), and (iv) assessing stock status with prediction and production models.3. This paper introduces the package and demonstrate its usage for a traditional stock assessment of a data-poor fish stock using a generated length-frequency (LFQ) data set. The simulation study shows the capability of these methods and identifies potential shortcomings of the traditional LFQ assessment.4. This toolbox modernises traditional stock assessment methods by easing application, development, and combination with advanced statistical approaches.
First results of the “Lean European Open Survey on SARS-CoV-2-Infected Patients (LEOSS)”
Creators: name: Jakob, Carolin E. M.
name: Borgmann, Stefan
name: Duygu, Fazilet
name: Behrends, Uta
name: Hower, Martin
name: Merle, Uta
name: Friedrichs, Anette
name: Tometten, Lukas
name: Hanses, Frank
name: Jung, Norma
name: Rieg, Siegbert
name: Wille, Kai
name: Grüner, Beate
name: Klinker, Hartwig
name: Gersbacher-Runge, Nicole
name: Hellwig, Kerstin
name: Eberwein, Lukas
name: Dolff, Sebastian
name: Rauschning, Dominic
name: Von Bergwelt-Baildon, Michael
name: Lanznaster, Julia
name: Strauß, Richard
name: Trauth, Janina
name: De With, Katja
name: Ruethrich, Maria
name: Lueck, Catherina
name: Nattermann, Jacob
name: Tscharntke, Lene
name: Pilgram, Lisa
name: Fuhrmann, Sandra
name: Classen, Annika
name: Stecher, Melanie
name: Schons, Maximilian
name: Spinner, Christoph
name: Vehreschild, Jörg Janne
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: SARS-CoV-2
subject: COVID-19
subject: LEOSS
subject: Cohort study
subject: DDC 610 / Medicine & health

description: Abstract Purpose Knowledge regarding patients’ clinical condition at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection is sparse. Data in the international, multicenter Lean European Open Survey on SARS-CoV-2-Infected Patients (LEOSS) cohort study may enhance the understanding of COVID-19. Methods Sociodemographic and clinical characteristics of SARS-CoV-2-infected patients, enrolled in the LEOSS cohort study between March 16, 2020, and May 14, 2020, were analyzed. Associations between baseline characteristics and clinical stages at diagnosis (uncomplicated vs. complicated) were assessed using logistic regression models. Results We included 2155 patients, 59.7% (1,287/2,155) were male; the most common age category was 66–85 years (39.6%; 500/2,155). The primary COVID-19 diagnosis was made in 35.0% (755/2,155) during complicated clinical stages. A significant univariate association between age; sex; body mass index; smoking; diabetes; cardiovascular, pulmonary, neurological, and kidney diseases; ACE inhibitor therapy; statin intake and an increased risk for complicated clinical stages of COVID-19 at diagnosis was found. Multivariable analysis revealed that advanced age [46–65 years: adjusted odds ratio (aOR): 1.73, 95% CI 1.25–2.42, p = 0.001; 66–85 years: aOR 1.93, 95% CI 1.36–2.74, p < 0.001; > 85 years: aOR 2.38, 95% CI 1.49–3.81, p < 0.001 vs. individuals aged 26–45 years], male sex (aOR 1.23, 95% CI 1.01–1.50, p = 0.040), cardiovascular disease (aOR 1.37, 95% CI 1.09–1.72, p = 0.007), and diabetes (aOR 1.33, 95% CI 1.04–1.69, p = 0.023) were associated with complicated stages of COVID-19 at diagnosis. Conclusion The LEOSS cohort identified age, cardiovascular disease, diabetes and male sex as risk factors for complicated disease stages at SARS-CoV-2 diagnosis, thus confirming previous data. Further data regarding outcomes of the natural course of COVID-19 and the influence of treatment are required.
Morphometric analyses in patients treated with subthreshold laser photocoagulation for central serous chorioretinopathy
Creators: name: Enders, Christian
name: Lang, Gabriele E.
name: Mayer, B.
name: Werner, Jens Ulrich
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Subthreshold lasercoagulation
subject: Optical coherence tomography
subject: DDC 610 / Medicine & health
subject: Central serous chorioretinopathy
subject: Laser coagulation
subject: Tomography, Optical coherence
subject: Retinopathie
subject: Lasertherapie
subject: Lichtkoagulation
subject: Optische Kohärenztomografie

description: Background and objective: To analyze changes in selected parameters in optical coherence tomography (OCT) after subthreshold laser coagulation (ST-LP) in patients with central serous chorioretinopathy (CSCR). Materials and methods: Fifty-four eyes of 49 patients with CSCR were included in the study. Each patient underwent therapy with ST-LP with a frequency-doubled Neodym-YAG Laser and OCT imaging. In OCT the thickness of the central subfield, cube volume, average cube thickness, volume under the ETDRS grid, and average thickness under the ETDRS grid were collected. Results: Decreases in total OCT volume and central retinal subfield thickness were statistically significant (p < 0.05). Possible correlations were observed between visual acuity at V3 (3 months after ST-LP) and Baseline and between central retinal subfield thickness at V1 (4 weeks after ST-LP) and visual acuity at BL. Conclusion: A decrease in retinal thickness and retinal volume could be shown after ST-LP. Central retinal subfield thickness measured by OCT could be a more sensitive measure than mean retinal thickness or macular volume for early detection of disease recurrence occurring in some patients 3 months after ST-LP.
Variational satisfiability solving: efficiently solving lots of related SAT problems
Creators: name: Young, Jeffrey M.
name: Bittner, Paul Maximilian
name: Walkingshaw, Eric
name: Thüm, Thomas
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Satisfiability solving
subject: Variation
subject: Choice calculus
subject: Software product lines
subject: DDC 000 / Computer science, information & general works
subject: Software product line engineering
subject: Softwareentwicklung

description: Incremental satisfiability (SAT) solving is an extension of classic SAT solving that enables solving a set of related SAT problems by identifying and exploiting shared terms. However, using incremental solvers effectively is hard since performance is sensitive to the input order of subterms and results must be tracked manually. For analyses that generate sets of related SAT problems, such as those in software product lines, incremental solvers are either not used or their use is not clearly described in the literature. This paper translates the ordering problem to an encoding problem and automates the use of incremental solving. We introduce variational SAT solving, which differs from incremental solving by accepting all related problems as a single variational input and returning all results as a single variational output. Variational solving syntactically encodes differences in related SAT problems as local points of variation. With this syntax, our approach automates the interaction with the incremental solver and enables a method to automatically optimize sharing in the input. To evaluate these ideas, we formalize a variational SAT algorithm, construct a prototype variational solver, and perform an empirical analysis on two real-world datasets that applied incremental solvers to software evolution scenarios. We show, assuming a variational input, that the prototype solver scales better for these problems than four off-the-shelf incremental solvers while also automatically tracking individual results.
Supplementary Material for: Vestibular Schwannoma Resection with Ipsilateral Simultaneous Cochlear Implantation in Patients with Normal Contralateral Hearing
Creators: name: Sanna, M.
name: Medina, M.
name: Macak, A.
name: Rossi, G.
name: Sozzi, V.
name: Prasad, S.C.
Publisher: name: Karger Publishers
Year: 2016
Subjects: Medicine

description: Objective: To report the hearing results of cochlear implantation simultaneous to vestibular schwannoma (VS) resection by means of a translabyrinthine approach in patients with normal contralateral hearing. Methods: This was a prospective study including adults with sporadic VS. Tumors were resected by means of a modified translabyrinthine approach with preservation of the cochlear nerve. Results: A total of 13 patients underwent cochlear implantation. At 14 months, the mean pure-tone audiogram was 56 dB. The mean speech recognition was 80%. Cochlear implantation provides monaural and binaural benefits in all the conditions tested, including sound localization. Conclusions: Cochlear implantation can be safely performed simultaneously to VS resection with satisfactory hearing results provided that the cochlear nerve is anatomically intact.
Model studies on the formation of the solid electrolyte interphase: reaction of Li with ultrathin adsorbed ionic-liquid films and Co3O4(111) thin films
Creators: name: Forster‐Tonigold, Katrin
name: Kim, Jihyun
name: Bansmann, Joachim
name: Groß, Axel
name: Buchner, Florian
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: cobalt oxide
subject: density functional theory
subject: ionic liquids
subject: solid electrolyte interphase
subject: DDC 530 / Physics
subject: DDC 540 / Chemistry & allied sciences
subject: Density functionals
subject: Surface chemistry
subject: Oberflächenchemie

description: The formation of the solid electrolyte interphase at the electrode-electrolyte interface is studied by X-ray photoelectron spectroscopy and dispersion-corrected density functional theory calculations. The interaction between an adsorbed ionic liquid, Li, and a Co3O4(111) thin-film model anode reveals bis(trifluoromethylsulfonyl)imide and 1-butyl-1-methylpyrrolidinium decomposition and lithiation of the cobalt oxide. In this work we aim towards the molecular understanding of the solid electrolyte interphase (SEI) formation at the electrode electrolyte interface (EEI). Herein, we investigated the interaction between the battery-relevant ionic liquid (IL) 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide (BMP-TFSI), Li and a Co3O4(111) thin film model anode grown on Ir(100) as a model study of the SEI formation in Li-ion batteries (LIBs). We employed mostly X-ray photoelectron spectroscopy (XPS) in combination with dispersion-corrected density functional theory calculations (DFT-D3). If the surface is pre-covered by BMP-TFSI species (model electrolyte), post-deposition of Li (Li+ ion shuttle) reveals thermodynamically favorable TFSI decomposition products such as LiCN, Li2NSO2CF3, LiF, Li2S, Li2O2, Li2O, but also kinetic products like Li2NCH3C4H9 or LiNCH3C4H9 of BMP. Simultaneously, Li adsorption and/or lithiation of Co3O4(111) to LinCo3O4 takes place due to insertion via step edges or defects; a partial transformation to CoO cannot be excluded. Formation of Co0 could not be observed in the experiment indicating that surface reaction products and inserted/adsorbed Li at the step edges may inhibit or slow down further Li diffusion into the bulk. This study provides detailed insights of the SEI formation at the EEI, which might be crucial for the improvement of future batteries.
Nucleus replacement could get a new chance with annulus closure
Creators: name: Zengerle, Laura
name: Köhler, Anne
name: Debout, Elisabeth
name: Hackenbroch, Carsten
name: Wilke, Hans-Joachim
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Lumbar disc herniation
subject: Nucleotomy
subject: Nucleus replacement
subject: Annulus repair
subject: In vitro study
subject: INTERVERTEBRAL DISC
subject: COMPRESSION
subject: FIBROSUS
subject: OUTCOMES
subject: HEIGHT
subject: SPINE
subject: MICRODISCECTOMY
subject: DISKECTOMY
subject: MECHANICS
subject: DDC 610 / Medicine & health

description: Abstract Purpose Disc herniations are usually treated by decompression of the spinal nerves via a partial nucleotomy. As a consequence of reduced disc height (DH), reduced intradiscal pressure (IDP) and increased range of motion (ROM), accelerated degeneration may occur. Nucleus replacement implants are intended to restore those values, but are associated with the risk of extrusion. Methods In six fresh frozen lumbar spinal segments (L2-3/L3-4/L4-5/L5-S1, age median 64.5 years (57–72), Pfirrmann grade 2–3), a prolapse was provoked through a box defect (6 × 10 mm) in the annulus. The herniated nucleus material was removed and replaced by a novel collagen-based nucleus implant. An annulus closure device sealed the defect. ROM, neutral zone (NZ) and IDP were measured in the (1) intact and (2) defect state, (3) postoperatively and (4) after cyclic loading (n = 100,000 cycles) applying pure moments (± 7.5 Nm) in flexion–extension, lateral bending and axial rotation. Additionally, the change in DH was determined. Extrusion of implants or nucleus material was evaluated macroscopically. Results In all specimens, a prolapse could be provoked which decreased DH. Subsequent nucleotomy changed ROM/NZ and IDP considerably. Initial values could be restored by the implantation. Macroscopically, none of the implants nor nucleus material did migrate after cyclic loading. Conclusions In this study, a prolapse followed by a nucleotomy resulted in a biomechanical destabilisation. Implantation of the nucleus replacement combined with an annulus closure restored the intact condition without showing signs of extrusion nor migration after cyclic loading. Hence, nucleus replacements could have a new chance in combination with annulus closure devices.
Stable carbon isotope analyses offer insights into net carbon degradation of maize silages in anaerobic batch fermentations
Creators: name: Einfalt, Daniel
name: Werth, Martin
name: Schropp, Daniel
name: Kazda, Marian
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: δ13C
subject: Net carbon degradation
subject: Maize silage
subject: DDC 570 / Life sciences
subject: Stable isotopes
subject: Biogas
subject: Stabiles Isotop

description: Abstract Carbon degradation indicates the efficiency of anaerobic digestion processes. Common carbon degradation determination methods define gross carbon degradation (C deggross) of substrate and inoculum inseparably. The aim of this study was to test an isotope-based method defining solely substrate-based net carbon degradation (C degnet) on maize silage. As the natural abundance of stable isotopes in agricultural substrates vary, the method’s applicability was tested on (i) different maize silages sampled from agricultural farms, (ii) maize silage in fresh (MSfresh) and impaired storage (MSimpaired) conditions.Experiments included six maize silages digested in a total of 19 lab-scale batch reactors, analyzed for digestion parameters, stable isotopes, gross and net carbon degradation. MSimpaired showed significantly different stable carbon isotope composition at the start of the experiments, compared to MSfresh. Both methods indicated quality losses in MSimpaired. Results showed significantly higher C degnet values, ranging from 58.4% to 86.5%, compared to deggross values, ranging from 23.1% to 48.7%. This indicated the applicability of an isotope-based method C degnet to assess net carbon degradation of maize silages more detailed by excluding the masking effect of the inoculum. The isotope-based net carbon degradation method was found applicable on maize silages from (i) different farms and (ii) in different storage qualities.
Predicting the presence of tinnitus using ecological momentary assessments
Creators: name: Breitmayer, Marius
name: Stach, Michael
name: Kraft, Robin
name: Allgaier, Johannes
name: Reichert, Manfred
name: Schlee, Winfried
name: Probst, Thomas
name: Langguth, Berthold
name: Pryss, Rüdiger
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: Signs and symptoms
subject: DDC 000 / Computer science, information & general works
subject: DDC 610 / Medicine & health
subject: Computer science
subject: Symptoms
subject: Informatik

description: Mobile applications have gained popularity in healthcare in recent years. These applications are an increasingly important pillar of public health care, as they open up new possibilities for data collection and can lead to new insights into various diseases and disorders thanks to modern data analysis approaches. In this context, Ecological Momentary Assessment (EMA) is a commonly used research method that aims to assess phenomena with a focus on ecological validity and to help both the user and the researcher observe these phenomena over time. One phenomenon that benefits from this capability is the chronic condition tinnitus. TrackYourTinnitus (TYT) is an EMA-based mobile crowdsensing platform designed to provide more insight into tinnitus by repeatedly assessing various dimensions of tinnitus, including perception (i.e., perceived presence). Because the presence of tinnitus is the dimension that is of great importance to chronic tinnitus patients and changes over time in many tinnitus patients, we seek to predict the presence of tinnitus based on the not directly related dimensions of mood, stress level, arousal, and concentration level that are captured in TYT. In this work, we analyzed a dataset of 45,935 responses to a harmonized EMA questionnaire using different machine learning techniques. In addition, we considered five different subgroups after consultation with clinicians to further validate our results. Finally, we were able to predict the presence of tinnitus with an accuracy of up to 78% and an AUC of up to 85.7%.
title: Lese-, Alltagsmathematik- und Problemlösekompetenzen von Erwachsenen in der Schweiz
title: Erste Resultate der PIAAC-Erhebung 2022/2023
titleType: Subtitle
Creators: name: Bundesamt für Statistik
Publisher: name: Bundesamt für Statistik
publisherIdentifier: https://ror.org/027h8t796
publisherIdentifierScheme: ROR
Year: 2024

description: Das internationale Programm zur Evaluation der Kompetenzen von Erwachsenen - Programme for the International Assessment of Adult Competencies (PIAAC) - ist eine internationale Studie der Organisation für wirtschaftliche Zusammenarbeit und Entwicklung (OECD) zu grundlegenden Kompetenzen von Erwachsenen, die alle zehn Jahre durchgeführt wird. Bei der Durchführung 2022/2023 nahmen 31 Mitgliedstaaten und Partnerländer der OECD teil - darunter auch erstmals die Schweiz. Wie im ersten Erhebungszyklus wurden Kompetenzen im Bereich Lesen und Alltagsmathematik gemessen, sowie neu im adaptiven Problemlösen. Der Bericht präsentiert die ersten Ergebnisse von PIAAC für die Schweiz im internationalen Vergleich sowie nach Gross- und Sprachregionen. Er untersucht die Kompetenzniveaus der Bevölkerung anhand soziodemografischer Merkmale wie Geschlecht, Alter, Bildungsstand, Arbeitsmarktstatus und Migrationsprofil. Zudem werden die Gruppen mit den geringen Grundkompetenzen näher beschrieben.
Systemic therapy for metastatic pancreatic cancer
Creators: name: Ettrich, Thomas J.
name: Seufferlein, Thomas
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Pancreatic cancer
subject: Metastatic
subject: Chemotherapy
subject: Systemic therapy
subject: Review
subject: DDC 610 / Medicine & health
subject: Pancreas; Cancer
subject: Pancreatic neoplasms; Drug therapy
subject: Neoplasm metastasis
subject: Bauchspeicheldrüsenkrebs
subject: Metastase
subject: Chemotherapie

description: Pancreatic cancer is mainly diagnosed at an advanced, often metastatic stage and still has a poor prognosis. Over the last decades, chemotherapy of metastatic pancreatic cancer (mPDAC) has proven to be superior to a mere supportive treatment with respect to both survival and quality of life. Recently, even sequential treatment of mPDAC could be established. Options for first-line treatment are combination chemotherapy regimens such as FOLFIRINOX and gemcitabine plus nab-paclitaxel when the performance status of the patient is good. For patients with poorer performance status, gemcitabine single-agent treatment is a valid option. Recently, the PARP inhibitor olaparib has been demonstrated to improve progression-free survival when used as a maintenance treatment in the subgroup of patients with mPDAC and a BRCA1/-2 germ line mutation having received at least 16 weeks of platinum-based chemotherapy. This group of patients also benefits from platinum-based chemotherapy combinations. Therefore, the BRCA1/-2 stats should be examined early in patients with mPDAC even when the occurrence of these mutations is only about 5% in the general Caucasian population. After the failure of first-line treatment, patients should be offered a second-line treatment if their ECOG permits further treatment. Here, the combination of 5-FU/FA plus nanoliposomal irinotecan has shown to be superior to 5-FU/FA alone with respect to overall survival. Immune checkpoint inhibitors like PD1/PD-L1 mAbs are particularly efficacious in tumors with high microsatellite instability (MSI-h). Limited data in mPDACs shows that only a part of the already small subgroup of MSI-H mPDACs (frequency about 1%) appears to benefit substantially from a checkpoint inhibitor treatment. The identification of further subgroups, e.g., tumors with DNA damage repair deficiency, gene fusions, as well as novel approaches such as tumor-organoid-informed treatment decisions, may further improve therapeutic efficacy.
Electronic Supporting Material from Elongated magnetite nanoparticle formation from a solid ferrous precursor in a magnetotactic bacterium
Creators: name: Baumgartner, Jens
name: Menguy, Nicolas
name: Gonzalez, Teresa Perez
name: Morin, Guillaume
name: Widdrat, Marc
name: Faivre, Damien
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Biochemistry
subject: Geochemistry
subject: FOS: Earth and related environmental sciences
subject: 90301 Biomaterials
subject: FOS: Medical engineering

description: Magnetotactic bacteria are aquatic microorganisms that intracellularly mineralize ferrimagnetic nanoparticles enabling the cells to align with the geomagnetic field. The bacteria produce a magnetic mineral of species-specific phase (magnetite Fe(II)Fe(III)2O4 or greigite Fe(II)Fe(III)2S4), size, morphology and particle assembly. Several species produce crystals of unusual elongated particle shapes, which break the symmetry of the thermodynamically favoured isometric morphology. Such morphologies are thought to affect domain size and orientation of the internal magnetization. Therefore, they are interesting study objects to develop new synthetic strategies for the morphological control of nanoparticles. We investigate the formation of such irregularly shaped nanomagnets in the species Desulfovibrio magneticus RS-1. In contrast to previously described organisms, this bacterium accumulates iron predominantly as Fe(II) rather than Fe(III) consistent with an alternative oxidative biomineralization route. Further, using high-resolution electron microscopy, we observe an epitaxial relationship between precursor and the final mineral phase supporting the notion of a solid-state transformation pathway. The precursor is likely a green rust previously thought to convert to magnetite only by dissolution and re-precipitation. Our findings represent a novel observation in the interconversion of iron (oxyhydr)oxide materials and suggest that solid-state growth processes could be required to produce irregularly shaped, elongated magnetite nanocrystals.
Procedure
Creators: name: Gaona, Mayra Alejandra
name: Lopez, Josselin
name: Adilene Osnaya
name: Taylor-Ritzler, Tina
Publisher: name: OSF Registries
Year: 2017

description: ___________________
Study One
After recruitment through MTurk, participants will be randomly assigned to the White privilege or Black disadvantage condition. First, the participants will open the survey and the initial screen will include the consent form. After consenting, the next screen will display an instruction paragraph prior to a list of 24 statements on White privileges or Black disadvantages. Participants will be asked to rate their level of agreement with each of these statements on a 1 (strongly disagree) to 7 (strongly agree) scale. Once participants are finished with this task, they will proceed to the next screen which will contain the Collective Guilt Index. Once participants have responded to the statements in this index, they will move on to the next page which contains the Racism Scale. Both, the collective guilt measure and the racism scale will be responded to on the same a 7-point scale as the first 24 statements. After this final scale is given and the study is completed, the final screen will contain debriefing information.

Study Two
After recruitment through MTurk, participants will be randomly assigned to the White privilege or Black disadvantage condition. First, the participants will open the survey and the initial screen will include the consent form. After consenting, the next screen will display an instruction paragraph asking participants to consider and write down ways in which either they have received privileges or been advantaged because of being White or in which African Americans have not received privileges or been disadvantaged because they are Black, depending on the condition. Once participants are finished with this task, they will proceed to a new screen where they will answer the Collective Guilt Index. Once participants have responded to the statements in this index, they will move on to the next page which contains the Racism Scale. Both, the collective guilt measure and the racism scale will be responded to on the same a 7-point scale as the first 24 statements. After this final scale is given and the study is completed, the final screen will contain debriefing information.
title: Die Ausbildungssituation der Kandidatinnen und Kandidaten der höheren Berufsbildung
title: Erste Ergebnisse der Erhebung zur höheren Berufsbildung 2023
titleType: Subtitle
Creators: name: Bundesamt für Statistik
Publisher: name: Bundesamt für Statistik
publisherIdentifier: https://ror.org/027h8t796
publisherIdentifierScheme: ROR
Year: 2024

description: Die höhere Berufsbildung bildet zusammen mit den Hochschulen die Tertiärstufe des schweizerischen Bildungssystems. Sie ermöglicht Berufsleuten mit einem eidgenössischen Fähigkeitszeugnis oder einem gleichwertigen Abschluss auf Sekundarstufe II eine Spezialisierung und eine Vertiefung ihres Fachwissens. Unter der höheren Berufsbildung werden die eidgenössischen Prüfungen (Berufsprüfung, höhere Fachprüfung) und die höheren Fachschulen zusammengefasst. Personen, die im Jahr 2022 einen Abschluss der höheren Berufsbildung angestrebt haben, wurden 2023 erstmals vom BFS zur ihrer Ausbildung befragt. Die vorliegende Publikation enthält die ersten Ergebnisse der Befragung 2023 von Prüfungskandidatinnen und -kandidaten der höheren Berufsbildung. Dabei stehen die soziodemografische Zusammensetzung, Fragen zur Ausbildung und die subjektive Einschätzungen der Kandidatinnen und Kandidaten sowie die Kosten und die Finanzierung der Ausbildung im Vordergrund. Um der Bandbreite der Ausbildungen Rechnung zu tragen, werden die Statistiken nach der internationalen Standardklassifikation des Bildungswesens (ISCED) aufgeschlüsselt.
Hypothesis
Creators: name: Taylor-Ritzler, Tina
name: Gaona, Mayra Alejandra
name: Adilene Osnaya
name: Lopez, Josselin
Publisher: name: OSF Registries
Year: 2017

description: The present study testes one hypothesis: If racial inequality is framed based on the privileges associated with being White rather than the disadvantages associated with being Black, then feelings of collective guilt would increase which would lead to a decrease in racist attitudes.
title: Conditions de formation des personnes candidates aux examens de la formation professionnelle supérieure
title: Premiers résultats de l'enquête sur la formation professionnelle supérieure de 2023
titleType: Subtitle
Creators: name: Office fédéral de la statistique
Publisher: name: Office fédéral de la statistique
publisherIdentifier: https://ror.org/027h8t796
publisherIdentifierScheme: ROR
Year: 2024

description: La formation professionnelle supérieure constitue, avec les hautes écoles, le degré tertiaire du système éducatif suisse. Elle permet aux professionnels titulaires d’un certificat fédéral de capacité ou d’un diplôme équivalent du degré secondaire II de se spécialiser et d’approfondir leurs connaissances professionnelles. La formation professionnelle supérieure englobe les examens fédéraux (examen professionnel, examen professionnel supérieur) et les écoles supérieures. Les personnes qui visaient un diplôme de la formation professionnelle supérieure en 2022 ont été interrogées pour la première fois en 2023 par l’OFS sur leur formation. Les premiers résultats de l’enquête 2023 sur les personnes candidates à un examen de la formation professionnelle supérieure sont présentés dans cette publication. L’accent est mis sur la composition sociodémographique de la population considérée, sur des questions relatives à la formation, sur la perception subjective des candidats interrogés et sur le financement de la formation. Les statistiques sont ventilées conformément à la classification internationale type de l’éducation (CITE) pour tenir compte de toute la palette des formations.