cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Mesochorus (Mesochorus) macrophyae SCHWENKE 1999
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus macrophyae

description: Mesochorus (Mesochorus) macrophyae SCHWENKE, 1999
Material examined: 1♀ 14-28.vii.
D i s t r i b u t i o n: Western Palaearctic, new record for Georgia and the Caucasus region.
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 110, DOI: 10.5281/zenodo.10415120
Εκτίμηση της λειτουργικότητας, φυσικής δραστηριότητας και επιπέδου άσκησης ασθενών που υποβλήθηκαν σε μονοδιαμερισματική αρθροπλαστική γόνατος
Creators: name: Ζαφειριάδης, Πέτρος Κωνσταντίνου
Publisher: name: Aristotle University of Thessaloniki
Year: 2024
Subjects: Οστεοαρθρίτιδα
Μονοδιαμερισματική Αρθροπλαστική Γόνατος
Ποιότητα ζωής
Osteoarthritis
Unicompartmental Knee Arthroplasty
Quality of life

description: Αυτή η σειρά περιπτώσεων αξιολογεί την αποτελεσματικότητα της έσω μονοδιαμερισματικής αρθροπλαστικής γόνατος (ΜΑΓ) στη θεραπεία της οστεοαρθρίτιδας τελικού σταδίου (ΟΑ) του έσω διαμερίσματος γόνατος με άθικτο πρόσθιο χιαστό σύνδεσμο. Εβδομήντα πέντε ασθενείς (95 γόνατα) υποβλήθηκαν σε πρωτογενή μεσαία κινητά MAΓ μεταξύ 2016 και 2021. Οι προεγχειρητικές και μετεγχειρητικές εκτιμήσεις περιλάμβαναν Βαθμολογία Κοινωνίας Γόνατος (KSS), EuroQoL-5 Διαστάσεις-5 Επίπεδα (EQ-5D-5L), κάμψη γόνατος, και μετεγχειρητικό Forgotten Joint Score (FJS)-12. Τα αποτελέσματα έδειξαν σημαντικές βελτιώσεις στα KSS, EQ-5D-5L, κάμψη γόνατος και FJS στο όριο παρακολούθησης 2 ετών. Τα ποσοστά επιπλοκών ήταν χαμηλά, με μόνο δύο επιφανειακές λοιμώξεις του δέρματος να επιλύονται με από του στόματος αντιβιοτικά και δεν αναφέρθηκαν σοβαρές επιπλοκές ή αναθεωρήσεις.
description: This case series evaluates the efficacy of medial unicompartmental knee arthroplasty (UKA) in treating end-stage osteoarthritis (OA) of the medial knee compartment with an intact anterior cruciate ligament. Seventy-five patients (95 knees) underwent primary medial mobile-bearing UKA between 2016 and 2021. Preoperative and postoperative assessments included Knee Society Score (KSS), EuroQoL-5 Dimensions-5 Levels (EQ-5D-5L), knee flexion, and postoperative Forgotten Joint Score (FJS)-12. Results showed significant improvements in KSS, EQ-5D-5L, knee flexion, and FJS at the 2-year follow-up mark. Complication rates were low, with only two superficial skin infections resolved with oral antibiotics and no serious complications or revisions reported.
Mesochorus (Mesochorus) marginatus THOMSON 1886
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus marginatus

description: Mesochorus (Mesochorus) marginatus THOMSON, 1886
M a t e r i a l e x a m i n e d: Trap4: 1♀ 20.v.-1.vi.
D i s t r i b u t i o n: Western Palaearctic, known from Georgia (RIEDEL et al. 2018, RIEDEL & JAPOSHVILI 2021).
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 110, DOI: 10.5281/zenodo.10415120
Additional file 10: of miR-519a enhances chemosensitivity and promotes autophagy in glioblastoma by targeting STAT3/Bcl2 signaling pathway
Creators: name: Li, Hong
name: Chen, Lei
name: Li, Jun-jie
name: Zhou, Qiang
name: Huang, Annie
name: Liu, Wei-wen
name: Wang, Ke
name: Gao, Liang
name: Qi, Song-tao
name: Lu, Yun-tao
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Table S3. Clinical information of patients with recurrent GBM. (DOCX 105Â kb)
Mesochorus (Mesochorus) pallipes BRISCHKE 1880
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus pallipes

description: Mesochorus (Mesochorus) pallipes BRISCHKE, 1880
M a t e r i a l e x a m i n e d: Trap 2: 1♀ 5-20.v., 1♀ 1-15.vi.; trap 7: 1♀ 27.vii.-20.viii.
D i s t r i b u t i o n: Western Palaearctic, known from Georgia (RIEDEL et al. 2018, RIEDEL & JAPOSHVILI 2021).
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 110, DOI: 10.5281/zenodo.10415120
Mesochorus (Mesochorus) pictilis HOLMGREN 1860
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus pictilis

description: Mesochorus (Mesochorus) pictilis HOLMGREN, 1860
M a t e r i a l e x a m i n e d: Trap2: 1♀ 1-15.vi.
D i s t r i b u t i o n: Holarctic, known from Georgia (RIEDEL et al. 2018).
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 110, DOI: 10.5281/zenodo.10415120
Demonstration of unconditional one-way quantum computations for continuous variables
Creators: name: Ukai, Ryuji
name: Iwata, Noriaki
name: Shimokawa, Yuji
name: Armstrong, Seiji C.
name: Politi, Alberto
name: Yoshikawa, Jun-ichi
name: van Loock, Peter
name: Furusawa, Akira
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum computing promises to exploit the laws of quantum mechanics for processing information in ways fundamentally different from today's classical computers, leading to unprecedented efficiency. One-way quantum computation, sometimes referred to as the cluster model of quantum computation, is a very promising approach to fulfil the capabilities of quantum information processing. The cluster model is realizable through measurements on a highly entangled cluster state with no need for controlled unitary evolutions. Here we demonstrate unconditional one-way quantum computation experiments for continuous variables using a linear cluster state of four entangled optical modes. We implement an important set of quantum operations, linear transformations, in the optical phase space through one-way computation. Though not sufficient, these are necessary for universal quantum computation over continuous variables, and in our scheme, in principle, any such linear transformation can be unconditionally and deterministically applied to arbitrary single-mode quantum states.
description: 9 pages, 3 figures
Threshold Upsilon-meson Photoproduction at EIC and EicC
Creators: name: Strakovsky, Igor I.
name: Briscoe, William J.
name: Pentchev, Lubomir
name: Schmidt, Axel
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: High-accuracy $Υ$-meson photoproduction data from EIC and EicC experiments will allow the measurement of the near-threshold total cross section of the reaction $γp\toΥp$, from which the absolute value of the $Υp$ scattering length, $|α_{Υp}|$, can be extracted using a Vector-Meson Dominance model. For this evaluation, we used $Υ$-meson photoproduction quasi-data from the QCD approach (the production amplitude can be factorized in terms of gluonic generalized parton distributions and the quarkonium distribution amplitude). A comparative analysis of $|α_{Υp}|$ with the recently determined scattering lengths for $ωp$, $ϕp$, and $J/ψp$ using the A2, CLAS, and GlueX experimental data are performed. The role of the "young" vector-meson effect is evaluated.
description: 6 pages, 6 figures, 3 tables
WS2 Monolayers Coupled to Hyperbolic Metamaterial Nanoantennas: Broad Implications for Light-Matter-Interaction Applications
Creators: name: Indukuri, S. R. K. Chaitanya
name: Frydendahl, Christian
name: Bar-David, Jonathan
name: Mazurski, Noa
name: Levy, Uriel
Publisher: name: arXiv
Year: 2021
Subjects: subject: Optics (physics.optics)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Due to their atomic layer thickness, direct bandgap, mechanical robustness and other superior properties, transition metal dichalcogenides (TMDCs) monolayers are considered as an attractive alternative to graphene for diverse optoelectronic applications. Yet, due to the very nature of atomic layer thickness, the interaction of light with TMDCs is limited, hindering overall efficiency for optical applications. Therefore, in order for TMDCs to become a true candidate as the material of choice for optoelectronics, there is a need for a mechanism which significantly enhances the interaction of light with TMDCs. In this paper, we demonstrate about 30-fold enhancement of the overall photoluminescence emission intensity from a WS2 monolayer, by its coupling to a hyperbolic metamaterial nanoantenna array. This enhancement corresponds to nearly 300-fold enhancement per individual nanoantenna. This overall enhancement is achieved by the combination of enhancing the excitation (absorption) efficiency, alongside with enhancing the radiative decay rate. Our result paves the way for the use of TMDCs in diverse optoelectronic applications, ranging from light sources and photodetectors to saturated absorbers and nonlinear media.
description: 26 pages, 4 figures. This document is the unedited Author's version of a Submitted Work that was subsequently accepted for publication in ACS Applied Nano Materials, copyright American Chemical Society, after peer review. To access the final edited and published work see: https://pubs.acs.org/doi/abs/10.1021/acsanm.0c02186
Mesochorus (Mesochorus) politus GRAVENHORST 1829
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus politus

description: Mesochorus (Mesochorus) politus GRAVENHORST, 1829
M a t e r i a l e x a m i n e d: Trap 2: 1♀ 7-21.ix.; trap 7: 1♀ 1-25.vi.; trap 12: 1♀ 15-29.vi., 2♀♀ 29.vi.-13.vii., 3♀♀ 13-27.vii., 3♀♀ 27.vii.-10.viii., 3♀♀ 10-24.viii., 1♀ 24.viii.-7.ix.; trap 15: 1♁ 30.vi.-14.vii., 1♀ 14-28.vii., 1♀ 11-25.viii.
D i s t r i b u t i o n: Transpalaearctic and Oriental, known from Georgia (RIEDEL et al. 2018, RIEDEL & JAPOSHVILI 2021).
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 110, DOI: 10.5281/zenodo.10415120
Additional file 1 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution
Creators: name: Yu, Xuexin
name: Lin, Wanrun
name: Spirtos, Alexandra
name: Wang, Yan
name: Chen, Hao
name: Ye, Jianfeng
name: Parker, Jessica
name: Liu, Ci Ci
name: Wang, Yiying
name: Quinn, Gabriella
name: Zhou, Feng
name: Chambers, Setsuko K.
name: Lewis, Cheryl
name: Lea, Jayanthi
name: Li, Bo
name: Zheng, Wenxin
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Computational Biology

description: Additional file 1: Figure S1. Two-dimensional t-SNE projection of 19,008 cells from fallopian tube of 6 samples. Distinct colors indicate the cells from different samples. Figure S2. Two-dimensional t-SNE projection of 3033 secretory and ciliated cells from 6 samples. Distinct colors indicate the cells from different samples. Figure S3. IHC staining confirms the existence of EMT cluster by its markers SFRP4 in epithelial and stromal compartments of a tubal section from BRCA1_2 (A), BRCA1_3 (B), Normal_1 (C) and Normal_2 (D).
Mesochorus (Mesochorus) punctipleuris THOMSON 1886
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus punctipleuris

description: Mesochorus (Mesochorus) punctipleuris THOMSON, 1886
M a t e r i a l e x a m i n e d: Trap 7: 2♀♀ 5-19.x.
D i s t r i b u t i o n: Holarctic, new record for Georgia and the Caucasus region.
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 111, DOI: 10.5281/zenodo.10415120
Mesochorus (Mesochorus) scandinavicus SCHWENKE 1999
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus scandinavicus

description: Mesochorus (Mesochorus) scandinavicus SCHWENKE, 1999
M a t e r i a l e x a m i n e d: Trap4:1♁29.vi.-13.vii.
D i s t r i b u t i o n: Western Palaearctic, new record for Georgia and the Caucasus region.
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 111, DOI: 10.5281/zenodo.10415120
Autosomal products of meiosis arising from radiation-induced interchange in female Drosophila Melanogaster
Creators: name: Gibson, William Glen
Publisher: name: University of British Columbia
Year: 2010

description: The present study was initiated with the view of achieving two goals: 1) to establish a suitable genetic assay system for measuring the frequency of spontaneous and induced structural and numerical aberrations of autosomes during meiosis in females and 2) to provide a better understanding of the mechanisms responsible for the production of the aberrant classes recovered. By selective exclusion of all regular meiotic products this system enabled the recovery of large numbers of aberrant products. The multiplier system served as an internal dosimeter and provided an estimate of the population size from which the aberrancies arose which in turn provided a measure of the frequencies of each event. The four different classes of exceptional meiotic products were named according to the source or the structural nature of the chromosomes: reductional nondisjunction as "matroclinous"; equational nondisjunction as "equationals"; loss of chromosome 2 as "patroclinous"; and the attachment of homologous arms as "compounds". The results suggest that two main factors affect the recovery of induced aberrations: of most importance is isosequentiality and of lesser importance is genetic background. The three classes of simultaneously recovered progeny (excluding equational nondisjunctions) arise from a common mechanism of induction; a mechanism which also accounts for free arm formation. The location of the breaks, the position of the chromatids and the method of reconstitution determine the type of aberration produced. The reconstitution of these breaks in aberrant ways are referred to as interchanges. Furthermore, it would appear that the reconstitutions are restricted in that euchromatic breaks attach to euchromatic breaks and heterochromatic to heterochromatic. Interchanges resulting from breaks on opposite sides of the centromeres of homologues result in the formation of non-sister compound chromosomes and from breaks on opposite sides of the centromeres of sister chromatids result in the formation of sister compound chromosomes. The interchange, if between heterologues, could lead to the nondisjunction of a pair of chromosomes and be recovered, as in the present study, as matroclinous progeny. The reciprocal product of the interchange between heterologues would produce an equal number of nullo eggs observed as patroclinous progeny, but if the dyad so formed is heteromorphic, i.e. chromatids of different length, it would result in the greater recovery of patroclinous progeny because of the preferential inclusion of the shorter chromatid. The evidence for interchange mediated aberrations is provided by the recovery of free arms of chromosome 2. Experimental support for these events is provided by the unequivocal identification of the centromeres involved, which, as in this study, is made possible through the use of metacentric autosomes.
Mesochorus (Mesochorus) semirufus HOLMGREN 1860
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus semirufus

description: Mesochorus (Mesochorus) semirufus HOLMGREN, 1860
M a t e r i a l e x a m i n e d: Trap 7: 1♁ 1-13.vi., 1♀ 13-27.vii., 1♀ 7-21.ix.
D i s t r i b u t i o n: Transpalaearctic and Oriental, known from Georgia (RIEDEL et al. 2018).
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 111, DOI: 10.5281/zenodo.10415120
ПЕЙОРАТИВНАЯ КОННОТАЦИЯ ИНТЕРНЕТ-ДИСКУРСА В СОВРЕМЕННОЙ РАЗГОВОРНОЙ РЕЧИ
Creators: name: Жумаева, Шохсанам
name: Шералиева, Мухлиса
Publisher: name: Zenodo
Year: 2023

description: В данной статье рассматривается один из видов коннотации интернет-дискурса в современной разговорной речи, а именно пейоративная коннотация.
LIBER Webinar "Citizen Science: two institutional viewpoints from the UK and Denmark"
Creators: name: Dr. Paul Ayris
name: Overgaard, Anne Kathrine
Publisher: name: Zenodo
Year: 2021
Subjects: citizen science

description: This webinar focused on the role of Citizen Science in research universities and libraries through two case studies: UCL office for Open Science and Scholarship and Citizen Science Knowledge Center at the University of Southern Denmark. After the webinar, participants:
 • Are able to achieve greater understanding of the role of Citizen Science in research-led universities;
 • Are able to identify practical ways to implement Citizen Science to include citizens as partners in research;
 • Know where to find the resources and skills needed to deliver Citizen Science practice

 The first speaker, Paul Ayris, Pro-Vice-Provost, UCL Library Services, Chief Executive of UCL Press and the chair of LIBER’s Citizen Science Working Group, looked at governance issues around Open Science and how they are being tackled in UCL (University College London). Using Citizen Science as an exemplar, Dr. Ayris looked at how engagement and decision making take place, what the challenges are in a university where much activity is de-centralised, and where Citizen Science fits into the University strategy.

 The second speaker, Anne Kathrine Overgaard, Head of Development, University of Southern Denmark and a member of LIBER’s Citizen Science Working Group, took the participants from the first thoughts about Citizens and Science at SDU to the Citizen Science Knowledge Centre launched January 1st, 2021. Ms Overgaard discussed their organisation, services, and tasks illustrated by concrete examples. Lastly, she addressed the library role in Citizen Science as a platform for strong and meaningful collaboration between Research, Citizens, and Society from a Faculty point of view.

 The webinar concluded with a Q&A session.
Mesochorus (Mesochorus) tenuiscapus THOMSON 1886
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus tenuiscapus

description: Mesochorus (Mesochorus) tenuiscapus THOMSON, 1886
M a t e r i a l e x a m i n e d: Trap4: 1♀ 10-24.viii.
D i s t r i b u t i o n: Western Palaearctic, known from Georgia (RIEDEL et al. 2018).
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 111, DOI: 10.5281/zenodo.10415120
Synthesis of Biologically Active Small Molecules: 
Different Approaches to Drug Design
Creators: name: Ianni, Cristina <1980>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2014
Subjects: CHIM/08 Chimica farmaceutica

description: In the past years, genome biology had disclosed an ever-growing kind of biological targets that emerged as ideal points for therapeutic intervention. Nevertheless, the number of new chemical entities (NCEs) translated into effective therapies employed in the clinic, still not observed. Innovative strategies in drug discovery combined with different approaches to drug design should be searched for bridge this gap. In this context organic synthetic chemistry had to provide for effective strategies to achieve biologically active small molecules to consider not only as potentially drug candidates, but also as chemical tools to dissect biological systems.
In this scenario, during my PhD, inspired by the Biology-oriented Synthesis approach, a small library of hybrid molecules endowed with privileged scaffolds, able to block cell cycle and to induce apoptosis and cell differentiation, merged with natural-like cores were synthesized. A synthetic platform which joined a Domino Knoevenagel-Diels Alder reaction with a Suzuki coupling was performed in order to reach the hybrid compounds. These molecules can represent either antitumor lead candidates, or valuable chemical tools to study molecular pathways in cancer cells. The biological profile expressed by some of these derivatives showed a well defined antiproliferative activity on leukemia Bcr-Abl expressing K562 cell lines.
A parallel project regarded the rational design and synthesis of minimally structurally hERG blockers with the purpose of enhancing the SAR studies of a previously synthesized collection. A Target-Oriented Synthesis approach was applied. Combining conventional and microwave heating, the desired final compounds were achieved in good yields and reaction rates. The preliminary biological results of the compounds, showed a potent blocking activity. The obtained small set of hERG blockers, was able to gain more insight the minimal structural requirements for hERG liability, which is mandatory to investigate in order to reduce the risk of potential side effects of new drug candidates.
A new tool to determine masses and mass profiles using gravitational flexion
Creators: name: Leonard, Adrienne
name: King, Lindsay J.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In a recent publication, an aperture mass statistic for gravitational flexion was derived and shown to be effective, at least with simulated data, in detecting massive structures and substructures within clusters of galaxies. Further, it was suggested that the radius at which the flexion aperture mass signal falls to zero might allow for estimation of the mass or density profile of the structures detected. In this paper, we more fully explore this possibility, considering the behaviour both of the peak signal and the zero-signal contours for two mass models--the singular isothermal sphere and Navarro-Frenk-White profiles--under varying aperture size, filter shape and mass concentration parameter. We demonstrate the effectiveness of the flexion aperture mass statistic in discriminating between mass profiles and concentration parameters, and in providing an accurate estimate of the mass of the lens, to within a factor of 1.5 or better. In addition, we compare the aperture mass method to a direct nonparametric reconstruction of the convergence from flexion measurements. We demonstrate that the aperture mass technique is much better able to constrain the shape of the central density profile, obtains much finer angular resolution in reconstructions, and does not suffer from ambiguity in the normalisation of the signal, in contrast to the direct method.
description: 14 pages, 11 figures, 4 tables, MNRAS accepted
Magnonic thermal transport using the quantum Boltzmann equation
Creators: name: Nakata, Kouki
name: Ohnuma, Yuichi
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present a formula for thermal transport in the bulk of Bose systems based on the quantum Boltzmann equation (QBE). First, starting from the quantum kinetic equation and using the Born approximation for impurity scattering, we derive the QBE of Bose systems and provide a formula for thermal transport subjected to a temperature gradient. Next, we apply the formula to magnons. Assuming a relaxation time approximation and focusing on the linear response regime, we show that the longitudinal thermal conductivity of the QBE exhibits the different behavior from the conventional. The thermal conductivity of the QBE reduces to the Drude-type in the limit of the quasiparticle approximation, while not in the absence of the approximation. Finally, applying the quasiparticle approximation to the QBE, we find that the correction to the conventional Boltzmann equation is integrated as the self-energy into the spectral function of the QBE, and this enhances the thermal conductivity. Thus we shed light on the thermal transport property of the QBE beyond the conventional.
description: 5+3 pages, 1 figure
Tensor triangular geometry and KK-theory
Creators: name: Dell'Ambrogio, Ivo
Publisher: name: arXiv
Year: 2010
Subjects: subject: K-Theory and Homology (math.KT)
subject: FOS: Mathematics
subject: 18E30, 19K35, 18G15

description: We present some results on equivariant KK-theory in the context of tensor triangular geometry. More specifically, for G a finite group, we show that the spectrum of the tensor triangulated subcategory of KK^G generated by the tensor unit contains as a retract a canonical copy of the Zariski spectrum of the complex character ring of G. For G trivial, this inclusion is a homeomorphism. We also prove a general criterion for a support theory on a compactly generated tensor triangulated category to provide the universal support datum, in the sense of Paul Balmer, on its subcategory of compact objects.
description: 33 pages, updated some references as in published version
The discrete dipole approximation for periodic targets I. theory and tests
Creators: name: Draine, B. T.
name: Flatau, P. J.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The discrete-dipole approximation (DDA) is a powerful method for calculating absorption and scattering by targets that have sizes smaller than or comparable to the wavelength of the incident radiation. The DDA can be extended to targets that are singly- or doubly-periodic. We generalize the scattering amplitude matrix and the 4 x 4 Mueller matrix to describe scattering by singly- and doubly-periodic targets, and show how these matrices can be calculated using the DDA. The accuracy of DDA calculations using the open-source code DDSCAT is demonstrated by comparison to exact results for infinite cylinders and infinite slabs. A method for using the DDA solution to obtain fields within and near the target is presented, with results shown for infinite slabs.
description: 19 pages, 7 figures, submitted to J. Opt. Soc. Am. A
Dynamic Phase Transition in Prisoner's Dilemma on a Lattice with Stochastic Modifications
Creators: name: Saif, M. Ali
name: Gade, Prashant M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: We present a detailed study of prisoner's dilemma game with stochastic modifications on a two-dimensional lattice, in presence of evolutionary dynamics. By very nature of the rules, the cooperators have incentive to cheat and the fear to being cheated in prisoner's dilemma and may cheat even when not dictated by evolutionary dynamics. We consider two variants. In either case, the agents mimic the action (cooperation or defection) in the previous timestep of the most successful agent in the neighborhood. Over and above this, the fraction p of cooperators spontaneously change their strategy to pure defector at every time step in the first variant. In the second variant, there are no pure cooperators. All cooperators keep defecting with probability p at every time-step. In both cases, the system switches from coexistence state to an all-defector state for higher values of p. We show that the transition between these states unambiguously belongs to directed percolation universality class in 2 + 1 dimension. We also study the local persistence and the persistence exponents are higher than ones obtained in previous studies underlining their dependence on details of dynamics
description: 20 pages, 25 figures. to appear in JSTAT
CME-Driven and Flare-Ignited Fast Magnetosonic Waves Successively Detected in a Solar Eruption
Creators: name: Zhou, Xinping
name: Shen, Yuandeng
name: Su, Jiangtao
name: Tang, Zehao
name: Zhou, Chengrui
name: Duan, Yadan
name: Tan, Song
Publisher: name: arXiv
Year: 2021
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present SDO/AIA observation of three types of fast-mode propagating magnetosonic waves in a GOES C3.0 flare on 2013 April 23, which was accompanied by a prominence eruption and a broad coronal mass ejection (CME). During the fast rising phase of the prominence, a large-scale dome-shaped extreme ultraviolet (EUV) wave firstly formed ahead of the CME bubble and propagated at a speed of about 430 km/s in the CME's lateral direction. One can identify the separation process of the EUV wave from the CME bubble. The reflection effect of the on-disk counterpart of this EUV wave was also observed when it interacted with a remote active region. Six minutes after the first appearance of the EUV wave, a large-scale quasi-periodic EUV train with a period of about 120 seconds appeared inside the CME bubble, which emanated from the flare epicenter and propagated outward at an average speed up to 1100 km/s. In addition, another narrow quasi-periodic EUV wave train was observed along a closed-loop system connecting two adjacent active regions, which also emanated from the flare epicenter, propagated at a speed of about475 km/s and with a period of about 110 seconds. We propose that all the observed waves are fast-mode magnetosonic waves, in which the large-scale dome-shaped EUV wave ahead of the CME bubble was driven by the expansion of the CME bubble, while the large-scale quasi-periodic EUV train within the CME bubble and the narrow quasi-periodic EUV wave train along the closed-loop system were excited by the intermittent energy-releasing process in the flare. Coronal seismology application and energy carried by the waves are also estimated based on the measured wave parameters.
description: 25 pages, 6 figures and 2 tables, accepted for publication in Solar Physics
Mesochorus (Mesochorus) testaceus GRAVENHORST 1829
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus testaceus

description: Mesochorus (Mesochorus) testaceus GRAVENHORST, 1829
M a t e r i a l e x a m i n e d: Trap4: 1♀ 15-29.vi.
D i s t r i b u t i o n: Transpalaearctic, known from Georgia (RIEDEL et al. 2018).
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 111, DOI: 10.5281/zenodo.10415120
Spherical Non-Abelian Solutions in Conformal Gravity
Creators: name: Brihaye, Y.
name: Verbin, Y.
Publisher: name: arXiv
Year: 2009
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study static spherically-symmetric solutions of non-Abelian gauge theory coupled to Conformal Gravity. We find solutions for the self-gravitating pure Yang-Mills case as well as monopole-like solutions of the Higgs system. The former are localized enough to have finite mass and approach asymptotically the vacuum geometry of Conformal Gravity, while the latter do not decay fast enough to have analogous properties.
description: 12 pages, revised version, accepted for publication in Phys. Rev. D
Electron and phonon correlations in systems of one-dimensional electrons coupled to phonons
Creators: name: Chen, Leiming
Publisher: name: arXiv
Year: 2008
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Electron and phonon correlations in systems of one-dimensional electrons coupled to phonons are studied at low temperatures by emphasizing on the effect of electron-phonon backward scattering. It is found that the $2k_F$-wave components of the electron density and phonon displacement field share the same correlations. Both correlations are quasi-long-ranged for a single conducting chain coupled to one-dimensional or three-dimensional phonons, and they are long-ranged for repulsive electron-electron interactions for a three-dimensional array of parallel one-dimensional conducting chains coupled to three-dimensional phonons.
Radio frequency association of heteronuclear Feshbach molecules
Creators: name: Klempt, C.
name: Henninger, T.
name: Topic, O.
name: Scherer, M.
name: Kattner, L.
name: Tiemann, E.
name: Ertmer, W.
name: Arlt, J.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We present a detailed analysis of the production efficiency of weakly bound heteronuclear KRb-Feshbach molecules using radio frequency association in a harmonic trap. The efficiency was measured in a wide range of temperatures, binding energies and radio frequencies. A comprehensive analytical model is presented, explaining the observed asymmetric spectra and achieving good quantitative agreement with the measured production rates. This model provides a deep understanding of the molecule association process and paves the way for future experiments which rely on Feshbach molecules e.g. for the production of deeply bound molecules.
description: 5 pages, 4 figures
First results from a search for coherent elastic neutrino-nucleus scattering (CE$ν$NS) at a reactor site
Creators: name: Colaresi, J.
name: Collar, J. I.
name: Hossbach, T. W.
name: Kavner, A. R. L.
name: Lewis, C. M.
name: Robinson, A. E.
name: Yocum, K. M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: The deployment of a low-noise 3 kg p-type point contact germanium detector at the Dresden-II power reactor, 8 meters from its 2.96 GW$_{th}$ core, is described. This location provides an unprecedented (anti)neutrino flux of 8.1$\times 10^{13} ~\bar{ν_{e}}/$cm$^{2}$s. When combined with the 0.2 keV$_{ee}$ detector threshold achieved, a first measurement of CE$ν$NS from a reactor source appears to be within reach. We report on the characterization and abatement of backgrounds during initial runs, deriving improved limits on extensions of the Standard Model involving a light vector mediator, from preliminary data.
description: 7 pages, 7 figures
Mesochorus (Mesochorus) tipularius GRAVENHORST 1829
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus tipularius

description: Mesochorus (Mesochorus) tipularius GRAVENHORST, 1829
M a t e r i a l e x a m i n e d: Trap4: 1♀ 29.vi.-13.vii.
D i s t r i b u t i o n: Holarctic, new record for Georgia and the Caucasus region.
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 111, DOI: 10.5281/zenodo.10415120
Canonical formulation of gravitating spinning objects at 3.5 post-Newtonian order
Creators: name: Steinhoff, Jan
name: Wang, Han
Publisher: name: arXiv
Year: 2009
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The 3.5 post-Newtonian (PN) order is tackled by extending the canonical formalism of Arnowitt, Deser, and Misner to spinning objects. This extension is constructed order by order in the PN setting by utilizing the global Poincare invariance as the important consistency condition. The formalism is valid to linear order in the single spin variables. Agreement with a recent action approach is found. A general formula for the interaction Hamiltonian between matter and transverse-traceless part of the metric at 3.5PN is derived. The wave equation resulting from this Hamiltonian is considered in the case of the constructed formalism for spinning objects. Agreement with the Einstein equations is found in this case. The energy flux at the spin-orbit level is computed.
description: RevTeX, 19 pages, v2: published version
The mass distribution of a moderate redshift galaxy group and brightest group galaxy from gravitational lensing and kinematics
Creators: name: McKean, J. P.
name: Auger, M. W.
name: Koopmans, L. V. E.
name: Vegetti, S.
name: Czoske, O.
name: Fassnacht, C. D.
name: Treu, T.
name: More, A.
name: Kocevski, D. D.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The gravitational lens system CLASS B2108+213 has two radio-loud lensed images separated by 4.56 arcsec. The relatively large image separation implies that the lensing is caused by a group of galaxies. In this paper, new optical imaging and spectroscopic data for the lensing galaxies of B2108+213 and the surrounding field galaxies are presented. These data are used to investigate the mass and composition of the lensing structure. The redshift and stellar velocity dispersion of the main lensing galaxy (G1) are found to be z = 0.3648 +/- 0.0002 and sigma_v = 325 +/- 25 km/s, respectively. The optical spectrum of the lensed quasar shows no obvious emission or absorption features and is consistent with a BL Lac type radio source. However, the tentative detection of the G-band and Mg-b absorption lines, and a break in the spectrum of the host galaxy of the lensed quasar gives a likely source redshift of z = 0.67. Spectroscopy of the field around B2108+213 finds 51 galaxies at a similar redshift to G1, thus confirming that there is a much larger structure at z ~ 0.365 associated with this system. The width of the group velocity distribution is 694 +/- 93 km/s, but is non-Gaussian, implying that the structure is not yet viralized. The main lensing galaxy is also the brightest group member and has a surface brightness profile consistent with a typical cD galaxy. A lensing and dynamics analysis of the mass distribution, which also includes the newly found group members, finds that the logarithmic slope of the mass density profile is on average isothermal inside the Einstein radius, but steeper at the location of the Einstein radius. This apparent change in slope can be accounted for if an external convergence gradient, representing the underlying parent halo of the galaxy group, is included in the mass model.
description: 18 pages, 14 figures, 5 tables, accepted for publication in MNRAS
Mesochorus (Mesochorus) triangulus SCHWENKE 1999
Creators: name: Riedel
name: Pénigot
name: Schwarz
name: Diller
name: Johansson
name: Japoshvili, G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Mesochorus
Mesochorus triangulus

description: Mesochorus (Mesochorus) triangulus SCHWENKE, 1999
M a t e r i a l e x a m i n e d: Trap7: 1♀ 27.vii.-20.viii.
D i s t r i b u t i o n: Western Palaearctic, new record for Georgia and the Caucasus region.
description: Published as part of Riedel, Pénigot, Schwarz, Diller, Johansson & Japoshvili, G., 2023, Darwin wasps (Hymenoptera, Ichneumonidae) of the Kintrishi National Park, Sakartvelo (Georgia), with descriptions of six new species, pp. 61-153 in Linzer biologische Beiträge 55 (1) on page 111, DOI: 10.5281/zenodo.10415120
Effect on Higgs Boson Decays from Large Light-Heavy Neutrino Mixing in Seesaw Models
Creators: name: Chen, Jyong-Hao
name: He, Xiao-Gang
name: Tandean, Jusak
name: Tsai, Lu-Hsing
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: In seesaw models with more than one generation of light and heavy neutrinos, nu and N, respectively, it is possible to have sizable mixing between them for heavy-neutrino masses of order 100 GeV or less. We explore this possibility further, taking into account current experimental constraints, and study its effect on Higgs-boson decays in the contexts of seesaw models of types I and III. We find that in the type-I case the Higgs decay into a pair of light and heavy neutrinos, h -> nu N, could increase the total Higgs width in the standard model by up to almost 30% for a relatively light Higgs-boson, which would significantly affect Higgs searches at the LHC. The subsequent prompt decay of N into three light fermions makes this Higgs decay effectively a four-body decay. We further find that, in the presence of the large light-heavy mixing, these four-body Higgs decays can have rates a few times larger than their standard-model counterparts and therefore could provide a potentially important window to reveal the underlying seesaw mechanism.
description: 16 pages, 3 figures, with more discussion on experimental constraints and references, main conclusions unchanged, to match journal version
Trajectory control using an information engine
Creators: name: Saha, Tushar K.
name: Bechhoefer, John
Publisher: name: arXiv
Year: 2021
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We have built an information engine that can transport a bead in a desired direction by using favorable fluctuations from the thermal bath. However, in its original formulation, the information engine generates a fluctuating velocity and cannot control the position of the bead. Here, we introduce a feedback algorithm that can control the bead's position, to follow a desired trajectory. The bead can track the path if the maximum desired velocity is below the engine's maximum average velocity. Measuring the range of frequency that the feedback algorithm can track, we find a bandwidth that is slightly lower than the corner frequency of the bead in the trap.
description: 9 pages, 8 figures, published in Proc. SPIE 11798, Optical Trapping and Optical Micromanipulation XVIII, 117980L (1 August 2021)
Diastereoselective Formation of trans-HC(O)SH Through Hydrogenation of OCS on Interstellar Dust Grains
Creators: name: Molpeceres, Germán
name: de la Concepción, Juan García
name: Serra, Izaskun Jiménez
Publisher: name: arXiv
Year: 2021
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: With the presence of evermore complex S-bearing molecules being detected lately, studies on their chemical formation routes need to keep up the pace to rationalize observations, suggest new candidates for detection, and provide input for chemical evolution models. In this paper, we theoretically characterize the hydrogenation channels of OCS on top of amorphous solid water as an interstellar dust grain analog in molecular clouds. Our results show that the significant reaction outcome is trans-HC(O)SH, a recently detected prebiotic molecule toward G+0.693. The reaction is diastereoselective, explaining the seemingly absence of the cis isomer in the astronomical observations. We found that the reaction proceeds through a highly localized radical intermediate (cis-OCSH), which could be essential in the formation of other sulfur-bearing complex organic molecules due to its slow isomerization dynamics on top of amorphous solid water.
description: Accepted in ApJ
Algebraic Singularity Method for Mass Measurements with Missing Energy
Creators: name: Kim, Ian-Woo
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We propose a novel generalized method for mass measurements based on phase space singularity structures that can be applied to any event topology with missing energy. Our method subsumes the well-known end-point and transverse mass methods and yields new techniques for studying "missing particle" events, such as the double chain production of stable neutral particles at the LHC.
description: 4 pages, two columns, 5 figures, accepted for publication in PRL