cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Measuring redshift-space distortions with future SKA surveys
Creators: name: Raccanelli, A.
name: Bull, P.
name: Camera, Stefano
name: Bacon, D.
name: Blake, Chris
name: Doré, Olivier
name: Ferreira, Pedro G.
name: Maartens, Roy
name: Santos, Mario G.
name: Viel, M.
name: Zhao, G. B.
Publisher: name: Swinburne
Year: 2024

description: The peculiar motion of galaxies can be a particularly sensitive probe of gravitational collapse. As such, it can be used to measure the dynamics of dark matter and dark energy as well the nature of the gravitational laws at play on cosmological scales. Peculiar motions manifest themselves as an overall anisotropy in the measured clustering signal as a function of the angle to the line-ofsight, known as redshift-space distortion (RSD). Limiting factors in this measurement include our ability to model non-linear galaxy motions on small scales and the complexities of galaxy bias. The anisotropy in the measured clustering pattern in redshift-space is also driven by the unknown distance factors at the redshift in question, the Alcock-Paczynski distortion. This weakens growth rate measurements, but permits an extra geometric probe of the Hubble expansion rate. In this short chapter we will briefly describe the scientific background to the RSD technique, and forecast the potential of the SKA phase 1 and the SKA2 to measure the growth rate using both galaxy catalogues and intensity mapping, assessing their competitiveness with current and future optical galaxy surveys.
A terminology for downcycling
Creators: name: Helbig, Christoph
name: Huether, Jonas
name: Joachimsthaler, Charlotte
name: Lehmann, Christian
Publisher: name: My University
Year: 2022
Subjects: Kreislaufwirtschaft
Downcycling
Industrielle Ökologie
Recycling

description: The term downcycling is often used anecdotally to describe imperfections in recycling. However, it is rarely defined. Here, we identify six meanings of the term downcycling as used in scientific articles and reports. These encompass the material quality of reprocessed materials, target applications, product value, alloying element losses, material systems, and additional primary production. In a proposal for harmonized and more specific terminology, we define downcycling as the phenomenon of quality reduction of materials reprocessed from waste relative to their original quality. We further identify that the reduced quality can express itself thermodynamically, functionally, and economically, covering all perspectives on downcycling. Dilution, contamination, reduced demand for recycled materials, and design-related issues can cause those downcycling effects. We anticipate that this more precise terminology can help quantify downcycling, keep materials in the loop longer, use materials more often and at higher quality, and therefore assist in reducing material-related environmental impacts. © 2022 The Authors
unfinal shapes
Creators: name: Kepler, Patrick R
Publisher: name: University of Iowa
Year: 2022
Subjects: Burial
Cyanotype
Landscape
Memory
public abstract
Sculpture
Trauma

description: My work, unfinal shapes, combines cyanotype, sculpture, and installation to investigate the impacts of trauma and the shadow it casts upon memory, experience, and identity. These impacts do more than sunder the physical, they erode the interior—memories retreat, synaptic pathways contract, the shattered pieces of identity entomb. Trauma is not something that simply happens, but something that becomes. A shifting of self that rearranges to a shape that fits between the voids left behind. As the victim of abuse, the shape I took no longer feels like my own.
description: My practice is guided by an effect known as “memory amplification,” in which victims of traumatic events often recall those memories in exaggerated detail. Pain becomes heightened, and that memory transforms into something different. This “something different” is where my practice finds its purpose. I create new shapes from broken things. Using rotted wood and salvage as a proxy for self, I wrap these found objects in cyanotype fabric, which simultaneously act as documentation and death shroud. I then bury them for the earth to swallow and time to distort. Later, I exhume each item to reveal their new shape—a sculptural approximation of the something different that occurs in traumatic memory recall.
description: These bound memorials compel the viewer to consider the painful nature of the things long lost and perhaps remind them of our individual ability to lay them to rest. unfinal shapes is an invitation for others to contemplate the shapes of grief that haunt their memory by transforming the photographic into the sculptural.
Cognitive medicine - a new approach in health care science
Creators: name: Wallin, Anders
name: Kettunen, Petronella
name: Johansson, Per M.
name: Jonsdottir, Ingibjorg H.
name: Nilsson, Christer
name: Nilsson, Michael
name: Eckerstrom, Marie
name: Nordlund, Arto
name: Nyberg, Lars
name: Sunnerhagen, Katharina S.
name: Svensson, Johan
name: Terzis, Beata
name: Wahlund, Lars-Olof
name: Kuhn, H. Georg
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: Neurocognitive disorders
subject: Classification of diseases
subject: Disability
subject: Rehabilitation
subject: Mental functions
subject: Learning and memory
subject: Executive control
subject: Societal challenge
subject: Stress and environment
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background: The challenges of today’s society call for more knowledge about how to maintain all aspects of cognitive health, such as speed/attention, memory/learning, visuospatial ability, language, executive capacity and social cognition during the life course. Main text: Medical advances have improved treatments of numerous diseases, but the cognitive implications have not been sufficiently addressed. Disability induced by cognitive dysfunction is also a major issue in groups of patients not suffering from Alzheimer’s disease or related disorders. Recent studies indicate that several negative lifestyle factors can contribute to the development of cognitive impairment, but intervention and prevention strategies have not been implemented. Disability due to cognitive failure among the workforce has become a major challenge. Globally, the changing aging pyramid results in increased prevalence of cognitive disorders, and the diversity of cultures influences the expression, manifestation and consequences of cognitive dysfunction. Conclusions: Major tasks in the field of cognitive medicine are basic neuroscience research to uncover diverse disease mechanisms, determinations of the prevalence of cognitive dysfunction, health-economical evaluations, and intervention studies. Raising awareness for cognitive medicine as a clinical topic would also highlight the importance of specialized health care units for an integrative approach to the treatment of cognitive dysfunctions.
Mentor Behaviours: a field study of good practice mentoring behaviours in Australian aviation
Creators: name: Anca, Jose M.
Publisher: name: Swinburne
Year: 2024

description: Fifteen (15) mentor behaviours identified by more than 30 subject matter experts in Australian aviation was developed to form a Mentor Behaviour Questionnaire. The questionnaire was issued to a cohort of Australian commercial and airline transport pilots to further understand what good mentor behaviour "looks like" to a cross-section of Australian pilots. These variables are age, gender, age, flying time and training phase. A total of 157 pilots responded to the questionnaire.
Comparisons were made using the variables against all the 15 Mentor behaviours to understand the level of agreement (on a 7-point Likert scale) of the respondents to each of the mentor behaviours. The results of the comparisons are reported to further provide practical research support in developing practical guidance to aviation mentoring programs.
Assessment of post-traumatic osteoarthritis following tibial pilon fracture using weight bearing computed tomography
Creators: name: Carlson, Mitchell Riley
Publisher: name: University of Iowa
Year: 2022
Subjects: PTOA
Tibial pilon fractures
Weight bearing computed tomography
public abstract
Osteoarthritis

description: Post-traumatic osteoarthritis (PTOA) is a severely debilitating condition. Pilon fractures of the distal tibia particularly predispose the ankle to PTOA, with over 50% of these patients suffering from PTOA within five years of injury. However, it is not known which patients will develop this condition and which will remain healthy. Cartilage has very poor healing capabilities, so early detection and treatment of PTOA are imperative to minimize and avoid permanent damage to the joint. Furthermore, as new potential treatments for preventing PTOA arise, testing of their efficacy would be greatly accelerated by capabilities for early detection. Thus, there is a need for an early objective indicator for PTOA risk in patients recovering from tibial pilon fractures.
description: This study improved upon existing methods for monitoring PTOA initiation and progression, as well as for predicting outcome. A computational model was developed to predict PTOA risk in the ankle based on chronic contact stress elevation and early changes in joint space width. This model used 3D ankle scans acquired from a weight bearing CT scanner and custom-written code to compute contact stresses in the ankle. We were able to find a quantitative relationship between increased contact stresses and PTOA development in the ankle. This capability enables objective predictions of PTOA risk in these patients.
description: Early predictions for future changes in the joint may help us prescribe the most effective treatment, providing a basis to prevent permanent damage to the cartilage and preserve long-term joint function.
Statistical properties of mechanically generated surface gravity waves: A laboratory experiment in a three-dimensional wave basin
Creators: name: Onorato, M.
name: Cavaleri, L.
name: Fouques, S.
name: Gramstad, O.
name: Janssen, P. A E M
name: Monbaliu, J.
name: Osborne, A. R.
name: Pakozdi, C.
name: Serio, M.
name: Stansberg, C. T.
name: Toffoli, Alessandro
name: Trulsen, K.
Publisher: name: Swinburne
Year: 2024

description: A wave basin experiment has been performed in the MARINTEK laboratories, in one of the largest existing three-dimensional wave tanks in the world. The aim of the experiment is to investigate the effects of directional energy distribution on the statistical properties of surface gravity waves. Different degrees of directionality have been considered, starting from long-crested waves up to directional distributions with a spread of ±30° at the spectral peak. Particular attention is given to the tails of the distribution function of the surface elevation, wave heights and wave crests. Comparison with a simplified model based on second-order theory is reported. The results show that for long-crested, steep and narrow-banded waves, the second-order theory underestimates the probability of occurrence of large waves. As directional effects are included, the departure from second-order theory becomes less accentuated and the surface elevation is characterized by weak deviations from Gaussian statistics.
3870079.pdf
Creators: name: Konthasinghe, Kumarasiri
name: Chakraborty, Chitraleema
name: Mathur, Nikhil
name: Qiu, Liangyu
name: MUKHERJEE, ARUNABH
name: Fuchs, Gregory
name: Vamivakas, Nickolas
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Material
Consumers' perceptions of biocidal products in households
Creators: name: Olsson, Oliver
name: Wieck, Stefanie
name: Kümmerer, Klaus
Publisher: name: My University
Year: 2018
Subjects: Fragebogen
Risikokommunikation
Nachhaltige Chemie

description: Biocidal products are commonly used in households and can pose a risk to human health and the environment. The aim of this study was to evaluate consumers' use and understanding of biocidal products in order to identify starting points for minimising their exposure to these products and reducing possible emissions to the environment. In a case study, standardised questionnaires were used to interview consumers in 133 households in three neighbourhoods in Northern Germany, representing the urban-rural typologies in Europe: predominantly urban, intermediate and predominantly rural regions. The questions focussed on the comprehension of the term 'biocide', pest control habits, sources of information, risk perception of different product groups and possible emission reduction measures. Only 21% of the respondents understood the term 'biocide' correctly, whereas 29% thought of 'something that had to do with organic pest control', and 28% were not able to think of a possible meaning. The risk perception of biocidal products compared to plant protection products varied depending on the living conditions. In the urban neighbourhood, biocidal products were perceived as more dangerous than in the rural area. The main pests to be fought were ants, mould and fruit fly. The results of the study indicate that there is a considerable difference between the types of biocidal products that interviewees claimed to own and those that they actually did have in their households. Most notably, respondents did not realise that they owned surface disinfectants. This result indicates that consumers often seem not to be aware of using specific biocidal products. Also, this shows the limitations of collecting data on products owned with only one method, as the results from products inventories of the households deviate from the data collected in interviews. Our results show that the term 'biocide' is not fully understood by many people. To communicate possible risks of biocidal products, other terms would have to be used. Online information regarding general facts on necessary general hygiene measures and biocidal products against bacteria and insects are likely to be of highest relevance for consumers. However, risk communication for biocidal products in general is difficult because consumers are often not aware of using biocidal products. For this reason, information and awareness raising campaigns should be accompanied by further measures such as sales restrictions for specific user-groups or prohibitions of certain uses for a sustainable use of biocidal products. © 2017 Elsevier GmbH. All rights reserved.
Individual, family, and community correlates of child problematic behaviour in disadvantaged families.
Creators: name: Van Dieten, Marilyn.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1991
Subjects: subject: Psychology, Social.

description: Most investigators accept that the determination of risk status for child outcome is too complex to be explained by any single causal variable. Despite this recognition, few empirical attempts have been made to simultaneously examine the impact of multiple factors on child problematic behaviour. In the current study, a multivariate theoretical model was proposed to assess the relative and combined effects of various factors in contributing to child socialized aggression and conduct disturbance. Variables were drawn from four domains, including child problematic behaviour, family interaction, parent characteristics, and community factors. Analyses were also undertaken to identify protective factors which discriminated between problematic and nonproblematic children. The proposed theoretical model was tested with a high-risk community sample. Seventy-two families residing in rent-subsidized, high-crime neighbourhoods were recruited to participate in the study on a voluntary basis. All of the families were headed by single-mothers and the majority depended on social assistance as their primary source of income. In addition, children were equally represented on the basis of age, sex, and geographic location. The parent-child dyads were interviewed in the home. Multiple measures and/or modes of assessment (i.e., self-report, collateral reports, and observational techniques) were used to evaluate predictors from each of the major domains. Results of the multivariate analyses provided support for the proposed theoretical model. As expected, the most powerful predictor of socialized aggression and conduct disturbance emerged from the family interaction domain (i.e., ineffective discipline). Variables from the parent characteristics and community factors domain were also important in the prediction of socialized aggression. Combined, these measures accounted for a large percentage of the variance for each of the criterion measures. Path analytic techniques were used to examine the direct and indirect effects of predictor variables on child behavioural outcome. The results of these analyses pointed to the importance of previously neglected variables in this area. For example, parental antisocial attitudes were found to exert a direct impact on parenting behaviour (ineffective discipline, poor monitoring), which in turn increased the likelihood of child socialized aggression. The results also revealed that several protective factors were important in differentiating between problematic and nonproblematic children. Positive temperament, good academic performance, the ability to get along well with others, and the presence of a confidante tended to characterize children scoring low on measures of socialized aggression and conduct disturbance. The implications of these and other findings for theory, research, and clinical practice are discussed.
MPEC 2024-G205 : 2024 GS5
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 GS5

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Foreground subtraction in intensity mapping with the SKA
Creators: name: Wolz, L.
name: Abdalla, Filipe B.
name: Alonso, D.
name: Blake, Chris
name: Bull, P.
name: Chang, T. C.
name: Ferreira, Pedro G.
name: Kuo, Cheng Yu
name: Santos, Marios G.
name: Shaw, Richard
Publisher: name: Swinburne
Year: 2024

description: 21 cm intensity mapping experiments aim to observe the diffuse neutral hydrogen (HI) distribution on large scales which traces the Cosmic structure. The Square Kilometre Array (SKA) will have the capacity to measure the 21 cm signal over a large fraction of the sky. However, the redshifted 21 cm signal in the respective frequencies is faint compared to the Galactic foregrounds produced by synchrotron and free-free electron emission. In this article, we review selected foreground subtraction methods suggested to effectively separate the 21 cm signal from the foregrounds with intensity mapping simulations or data. We simulate an intensity mapping experiment feasible with SKA phase 1 including extragalactic and Galactic foregrounds. We give an example of the residuals of the foreground subtraction with a independent component analysis and show that the angular power spectrum is recovered within the statistical errors on most scales. Additionally, the scale of the Baryon Acoustic Oscillations is shown to be unaffected by foreground subtraction.
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease
Creators: name: Ehrnhoefer, Dagmar E.
name: Martin, Dale D. O.
name: Schmidt, Mandi E.
name: Qiu, Xiaofan
name: Ladha, Safia
name: Caron, Nicholas S.
name: Skotte, Niels H.
name: Nguyen, Yen T. N.
name: Vaid, Kuljeet
name: Southwell, Amber L.
name: Engemann, Sabine
name: Franciosi, Sonia
name: Hayden, Michael R.
Publisher: name: BioMed Central
Year: 2018

description: Huntington disease (HD) is caused by the expression of mutant huntingtin (mHTT) bearing a polyglutamine expansion. In HD, mHTT accumulation is accompanied by a dysfunction in basal autophagy, which manifests as specific defects in cargo loading during selective autophagy. Here we show that the expression of mHTT resistant to proteolysis at the caspase cleavage site D586 (C6R mHTT) increases autophagy, which may be due to its increased binding to the autophagy adapter p62. This is accompanied by faster degradation of C6R mHTT in vitro and a lack of mHTT accumulation the C6R mouse model with age. These findings may explain the previously observed neuroprotective properties of C6R mHTT. As the C6R mutation cannot be easily translated into a therapeutic approach, we show that a scheduled feeding paradigm is sufficient to lower mHTT levels in YAC128 mice expressing cleavable mHTT. This is consistent with a previous model, where the presence of cleavable mHTT impairs basal autophagy, while fasting-induced autophagy remains functional. In HD, mHTT clearance and autophagy may become increasingly impaired as a function of age and disease stage, because of gradually increased activity of mHTT-processing enzymes. Our findings imply that mHTT clearance could be enhanced by a regulated dietary schedule that promotes autophagy.
3870079.pdf
Creators: name: Konthasinghe, Kumarasiri
name: Chakraborty, Chitraleema
name: Mathur, Nikhil
name: Qiu, Liangyu
name: MUKHERJEE, ARUNABH
name: Fuchs, Gregory
name: Vamivakas, Nickolas
Publisher: name: Optica Publishing Group
Year: 2019
Subjects: Uncategorized

description: Supplemental Material
Determinants of Combined Factor Productivity of Ethiopian Manufacturing Firms
Creators: name: Mitiku, Amare
Publisher: name: Abyssinia Journal of Business and Social Sciences
Year: 2017

description: Due to lack of reliable data, combined factor productivity has not yet been computed in developing countries on non-erroneous bases. This would mislead to the identification of the determinants of Combined Factor Productivity (CFP). The aim of this section is to identify some of the possible determinants of CFP in Ethiopian manufacturing firms. The dynamic panel data estimation, using a system of GMM, has been a selected approach. It has been hypothesized that, among others, insufficiency of finance (working capital) would significantly affect the productivity of firms. Results from the analysis show that all factor intensities, at 1% significance and energy following with 5% significance level, both were having negative influence on combined factor productivity both in extended growth accounting model that includes Capital, Labor, Energy and Material (KLEM) and prime growth accounting model where only capital and labor (KL) are considered in the models. Shortage of foreign currency and working capital both as proxy of financial insufficiency, wielded significant effect on productivity in KLEM and KL models respectively at 10% level of significance. Export and training in their dummies have also shown positive and significant influence on combined factor productivity. This suggested that labour quantification results in loss of combined factor productivity gain unless accompanied by quality enhancement instruments such as training.
description: Abyssinia Journal of Business and Social Sciences, 2017: Vol. 2 No. 1
Selected Trade-Offs and risks associated with land use transitions in central Germany
Creators: name: Hoyer, Christian
name: Priess, Jörg A.
name: Jäckel, Greta
name: Schweitzer, Christian
Publisher: name: My University
Year: 2019
Subjects: Landwirtschaft
Flächennutzungswandel

description: Future uncertainties and risks for socio-environmental systems are often addressed in the form of scenarios. This study aims to identify the biggest future risks and uncertainties for the study region Central Germany and the question which land use changes and impacts on selected ecosystem services related to agricultural production can be expected in the coming decades. For this purpose, we co-developed scenario storylines along the largest uncertainties, how the region may change with different stakeholders and used environmental models to simulate land-use changes and impacts on selected ecosystem services related to agricultural production. The study revealed that Climate change may have beneficial (e.g. maize, sugar beet) or adverse effects (e.g. barley, wheat) on crop yield levels, depending on crop type and level of climate change. In the scenarios crop production is additionally influenced by different levels of regional preferences influencing crop land extent (e.g., afforestation), crop management (e.g., organic production), and crop types used for food or bioenergy production. As driving factors such as climate change, land availability, and land management all influence agriculture, integrated studies like this are needed to assess future crop production. However, sustainability objectives may prefer other than the most productive agricultural pathways providing additional benefits such as regulating or cultural services. © Springer International Publishing AG, part of Springer Nature 2019
title: Polychlorinated biphenyls in human serum
title: Diet, BMI, and diabetes
titleType: Subtitle
Creators: name: Lan, Tuo
Publisher: name: University of Iowa
Year: 2024
Subjects: subject: BMI
subject: Diet
subject: Human Serum
subject: PCBs
subject: Polychlorinated biphenyls
subject: Health sciences
subject: FOS: Health sciences
subject: public abstract
subject: Diabetes

description: Polychlorinated biphenyls (PCBs), a group of persistent and carcinogenic chemicals, have been suspected to contribute to diabetes risk by acting as endocrine disruptors. Despite a ban on the manufacture of PCBs in 1978 in the U.S., people are still exposed to PCBs through contaminated food and air. The goal of this study was to identify the determinants of serum PCBs, and to identify serum PCB congener profiles associated with diabetes. Specific Aim 1 sought to explore the relation between diet and serum concentrations of PCBs among a total of 76 children and their mothers, by assessing dietary exposure through the Dietary History Questionnaire II (DHQII) and measuring all PCB congeners in their serum and in food from where they shop. The analyses were performed by linear mixed models with households included as the random effect. We estimated a 10-fold decrease in dietary exposure to PCBs over the past two decades. We found that higher diet quality with less processed food, presented by Healthy Eating Index (HEI), was associated with higher serum concentrations of PCBs. Data from the National Health and Nutrition Examination Survey (NHANES) was used for Specific Aims 2 and 3. Specific Aim 2 sought to examine the association between dietary intake and serum levels of PCBs, and whether the association was modified by BMI, by utilizing linear regressions. We found that the association between dietary PCBs intake and serum levels of PCB was modified by BMI, with stronger associations in normal/underweight individuals and no statistically significant association in obese individuals. Specific Aim 3 sought to identify serum PCB congener profiles associated with diabetes, by utilizing classification tree and logistic regression methods. We revealed the combined associations of serum PCBs with diabetes.
description: In conclusion, this study provides evidence suggesting that the relationships between diet and serum PCB concentrations can vary in time and by BMI and PCB congeners. It also provides new insights into the combined associations of PCBs with diabetes. The findings of this dissertation support further avenues of research including how serum PCBs are associated with inhalation exposure, PCB sulfate metabolites, and PCBs in adipose tissues. Prospective studies with more detailed diabetes information (e.g., type of diabetes) are also needed to confirm the combined associations of PCBs with diabetes.
Identification of redundant faults.
Creators: name: Zhao, Hongdu.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Computer Science.

description: This thesis presents a redundancy identification (RI) method, namely, the Improved Structure Based (ISB) method, which identifies redundant faults in logic circuits. Redundant faults are those faults that are found not detectable by any test pattern in the process of automatic test pattern generation (ATPG) because they do not affect the normal circuit function. However, valuable time is wasted in ATPG algorithms due to the existence of redundant faults. The main purpose of ISB method is to locate redundant faults prior to applying ATPG algorithms. The ISB method does RI without search as opposed to most existing ATPG algorithms. The ISB method also presents significant improvement over existing structure-based methods for RI. The proposed ISB method can be applied efficiently to logic circuits with multiple-stem regions and multiple regions.
Pulsed homodyne Gaussian quantum tomography with low detection efficiency
Creators: name: Esposito, M.
name: Benatti, F.
name: Floreanini, R.
name: Olivares, S.
name: Randi, F.
name: Titimbo, K.
name: Pividori, M.
name: Novelli, Fabio
name: Cilento, F.
name: Parmigiani, F.
name: Fausti, D.
Publisher: name: Swinburne
Year: 2024

description: Pulsed homodyne quantum tomography usually requires a high detection efficiency, limiting its applicability in quantum optics. Here, it is shown that the presence of low detection efficiency (<50%) does not prevent the tomographic reconstruction of quantum states of light, specifically, of Gaussian states. This result is obtained by applying the so-called minimax adaptive reconstruction of the Wigner function to pulsed homodyne detection. In particular, we prove, by both numerical and real experiments, that an effective discrimination of different Gaussian quantum states can be achieved. Our finding paves the way to a more extensive use of quantum tomographic methods, even in physical situations in which high detection efficiency is unattainable.
Genomic and fitness consequences of heat stress-induced transposon mobilization in Drosophila
Creators: name: Atagozli, John
Publisher: name: University of Iowa
Year: 2025
Subjects: 3D chromatin architecture
Copy number
Fecundity
Heat shock
Transposable element
public abstract
Gene Expression

description: Transposable elements (TEs) are mobile genetic elements that can change their position or duplicate within the genome. They are also major components of most eukaryotic genomes. Importantly, the extent of their impact on genome function and evolution remains a matter of intense interrogation. To gain insight into this matter, the genomic and fitness consequences of heat shock-induced de novo transposon insertions were investigated in Drosophila melanogaster. Generationally repeated heat shock exposure resulted in copy number expansions of genomic retrotransposons as well as select rDNA elements. Interestingly, some of these copy number expansions were followed by plateaus and/or rapid reductions. These copy number changes were initially quantified via qPCR and Illumina next-generation sequencing methods. To overcome the limitations of these methods, Oxford Nanopore long-read sequencing was also employed to comprehensively annotate genomic insertion sites of transposons in the heat shock mutation accumulation lines (HSMALs). These results largely confirmed previous findings that retrotransposons were activated during heat shock events, although specific DNA transposons also showed significant increases in copy number. Furthermore, Hi-C analysis found that heat stress-induced de novo transposon insertions can alter the 3D chromatin architecture, as nearby TAD structures were altered at insertion sites. RNA-seq studies also demonstrate that gene expression was altered in HSMALs, likely due to de novo transposon insertions and/or changes in 3D chromatin architecture. Decreased fecundity in HSMALs indicates a mutational load was generated relative to control lines, likely as a result of transposon proliferation. This finding implicates heat shock-induced de novo transposon insertions as the causative agent for pervasive deleterious effects, whether through insertional mutagenesis or increased epigenetic repression of proximal genomic regions. Recovery of fecundity levels in inter-replicate crosses of HSMALs reveals that recessive mutations are associated with a large fraction of the detected deleterious effects.
Gesunde Luft
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2019
Subjects: subject: Luft
subject: Ozon
subject: Stickstoffdioxid
subject: Feinstaub
subject: NO2
subject: Luft
subject: Gesundheit
subject: Air
subject: Health

description: Das Magazin "Schwerpunkt" des Umweltbundesamtes widmet sich in jeder Ausgabe relevanten Themen im Bereich Umweltschutz. Es erscheint halbjährlich. In der Ausgabe 1-2019 beleuchtet das UBA das Themenfeld "Gesunde Luft": Was ist Luft eigentlich? Was gehört hinein und was nicht? Welche Schadstoffe beeinträchtigen die menschliche Gesundheit und was können wir dagegen tun. Detaillierte Artikel und Schaubilder zu Messstationen und der Berechnung der Krankheitslast erläutern wichtige weitere Felder zum Thema.
Branchen- und unternehmensgrößenbezogene Ermittlung von Klimaschutzpotenzialen (Schwerpunkt KMU) durch verstärkte Umsetzung von Energiemanagementmaßnahmen in der Wirtschaft
Creators: name: Rohde, Clemens
name: Plötz, Patrick
name: Nabitz, Lisa
Publisher: name: My University
Year: 2018
Subjects: subject: Klimaschutz
subject: Energieeffizienz
subject: Energieeffizenz
subject: Energieaudits
subject: Energiemanagement
subject: Klima | Energie

description: Ziel dieses Vorhabens war zu ermitteln, in welchem Umfang Energieaudits durchgeführt und Energiemanagementsysteme eingeführt sind, welche Hemmnisse der Umsetzung von hierbei identifizierten Maßnahmen zur Energieeffizienzverbesserung entgegenstehen, wie diese Hemmnisse gemindert werden können und welche zusätzlichen Energieeinsparpotenziale durch eine weitere Verbreitung von Energiemanagementsystemen erschlossen werden können.
Music on PBS: A History of Music Programming at a Community Radio Station
Creators: name: Lade, Rochelle
Publisher: name: Swinburne
Year: 2024

description: This historical case study explores the programs broadcast by Melbourne community radio station PBS from 1979 to 2019 and the way programming decisions were made. Data was gathered from archives, in-depth interviews and a quantitative analysis of programs broadcast over the four decades since PBS was founded in 1976. This research has found an inherent tension between the station's values of cooperative decision-making and the broadcasting of progressive music. Knowledge in the fields of community radio and music is advanced by exploring how cultural intermediaries at PBS made decisions to realise the station's goals of community access and participation.
3871104.pdf
Creators: name: Wang, Youmin
name: Zhou, Guangya
name: Zhang, Xiaosheng
name: Kwon, Kyungmok
name: Blanche, Pierre-Alexandre
name: Triesault, Nicholas
name: Yu, Kyoungsik
name: Wu, Ming
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental
WINGS: A WIde-field nearby Galaxy-cluster survey: III. Deep near-infrared photometry of 28 nearby clusters
Creators: name: Valentinuzzi, T.
name: Woods, David
name: Fasano, G.
name: Riello, M.
name: D'Onofrio, M.
name: Varela, J.
name: Bettoni, D.
name: Cava, A.
name: Couch, Warrick
name: Dressler, A.
name: Fritz, J.
name: Moles, M.
name: Omizzolo, A.
name: Poggianti, B. M.
name: Kjærgaard, P.
Publisher: name: Swinburne
Year: 2024

description: This is the third paper in a series devoted to the WIde-field Nearby Galaxy-cluster Survey (WINGS).WINGS is a long-term project aimed at gathering wide-field, multiband imaging and spectroscopy of galaxies in a complete sample of 77 X-ray selected, nearby clusters (0.04 < z < 0.07) located far from the galactic plane (|b| ≥ 20◦). The main goal of this project is to establish a local reference sample for evolutionary studies of galaxies and galaxy clusters. Aims. This paper presents the near-infrared (J, K) photometric catalogs of 28 clusters of the WINGS sample and describes the procedures followed to construct them. Methods. The raw data has been reduced at CASU and special care has been devoted to the final coadding, drizzling technique, astrometric solution, and magnitude calibration for the WFCAM pipeline-processed data. We constructed the photometric catalogs based on the final calibrated, coadded mosaics (≈0.79 deg2) in J (19 clusters) and K (27 clusters) bands. A customized interactive pipeline was used to clean the catalogs and to make mock images for photometric errors and completeness estimates. Results. We provide deep near-infrared photometric catalogs (90% complete in detection rate at total magnitudes J ≈ 20.5, K ≈ 19.4, and in classification rate at J ≈ 19.5 and K ≈ 18.5), giving positions, geometrical parameters, total and aperture magnitudes for all detected sources. For each field we classify the detected sources as stars, galaxies, and objects of “unknown” nature.
3871104.pdf
Creators: name: Wang, Youmin
name: Zhou, Guangya
name: Zhang, Xiaosheng
name: Kwon, Kyungmok
name: Blanche, Pierre-Alexandre
name: Triesault, Nicholas
name: Yu, Kyoungsik
name: Wu, Ming
Publisher: name: Optica Publishing Group
Year: 2019
Subjects: Uncategorized

description: Supplemental
Hegel et la pauvreté.
Creators: name: Le Fol, Pierre-François.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Philosophy.

description: Dans les Principes de la philosophie du droit , Hegel s'intéresse au problème de la pauvreté. Nous verrons dans cette thèse que le philosophe analyse le développement de la paupérisation comme un phénomène inhérent à la société civile. Nous nous intéresserons aussi aux effets que la pauvreté a sur la personne et également à ceux qu'elle a sur la société civile elle-même. Nous constaterons que Hegel ne semble pas offrir de remède à la pauvreté et nous nous interrogerons pour savoir si la raison de cette irrésolution n'est pas due à une conception capitaliste de la propriété privée, qui l'empêcherait de remettre en question la société civile. Pour cela, nous nous attacherons aux interprétations divergentes de Marcuse, de Harris et de Rose. Nous prendrons enfin position vis-à-vis de cette question pour montrer que Hegel n'est pas un défenseur acharné de la propriété dans sa forme bourgeoise et que ses développements sur la corporation dans les Principes de la philosophie du droit laissent entrevoir une solution au problème de la pauvreté par un changement d'esprit au coeur même de la société civile.
3874140.pdf
Creators: name: Ye, Yu
name: Liu, Fang
name: Wang, Mengxuan
name: Tai, Lixuan
name: Cui, Kaiyu
name: Feng, Xue
name: Zhang, Wei
name: Huang, Yidong
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: supplementary
WINGS-SPE spectroscopy in the wide-field nearby galaxy-cluster survey
Creators: name: Cava, A.
name: Bettoni, D.
name: Poggianti, B. M.
name: Couch, Warrick
name: Moles, M.
name: Varela, J.
name: Biviano, A.
name: D'Onofrio, M.
name: Dressler, A.
name: Fasano, G.
name: Fritz, J.
name: Kjærgaard, P.
name: Ramella, M.
name: Valentinuzzi, T.
Publisher: name: Swinburne
Year: 2024

description: Aims. We present the results from a comprehensive spectroscopic survey of the WINGS (WIde-field Nearby Galaxy-cluster Survey) clusters, a program called WINGS-SPE. The WINGS-SPE sample consists of 48 clusters, 22 of which are in the southern sky and 26 in the north. The main goals of this spectroscopic survey are: (1) to study the dynamics and kinematics of the WINGS clusters and their constituent galaxies, (2) to explore the link between the spectral properties and the morphological evolution in different density environments and across a wide range of cluster X-ray luminosities and optical properties. Methods. Usingmulti-object fiber-fed spectrographs, we observed our sample of WINGS cluster galaxies at an intermediate resolution of 6-9 and, using a cross-correlation technique, we measured redshifts with a mean accuracy of ~45 km s1. Results. We present redshift measurements for 6137 galaxies and their first analyses. Details of the spectroscopic observations are reported. TheWINGS-SPE has ~30% overlap with previously published data sets, allowing us both to perform a complete comparison with the literature and to extend the catalogs. Conclusions. Using our redshifts, we calculate the velocity dispersion for all the clusters in the WINGS-SPE sample.We almost triple the number of member galaxies known in each cluster with respect to previous works. We also investigate the X-ray luminosity vs. velocity dispersion relation for our WINGS-SPE clusters, and find it to be consistent with the form Lx 4v.
title: Comparative Analysis of Different Platelet Lysates and Platelet Rich Preparations to Stimulate Tendon Cell Biology
title: an In Vitro Study
titleType: Subtitle
Creators: name: Klatte-Schulz, Franka
name: Schmidt, Tanja
name: Uckert, Melanie
name: Scheffler, Sven
name: Kalus, Ulrich
name: Rojewski, Markus
name: Schrezenmeier, Hubert
name: Pruss, Axel
name: Wildemann, Britt
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: platelet rich plasma
subject: platelet lysate
subject: tenocyte-like cells
subject: tendon healing
subject: cell culture
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The poor healing potential of tendons is still a clinical problem, and the use of Platelet Rich Plasma (PRP) was hypothesized to stimulate healing. As the efficacy of PRPs remains unproven, platelet lysate (PL) could be an alternative with its main advantages of storage and characterization before use. Five different blood products were prepared from 16 male donors: human serum, two PRPs (Arthrex, (PRP-ACP); RegenLab (PRP-BCT)), platelet concentrate (apheresis, PC), and PL (freezing-thawing destruction of PC). Additionally, ten commercial allogenic PLs (AlloPL) from pooled donors were tested. The highest concentration of most growth factors was found in AlloPL, whereas the release of growth factors lasted longer in the other products. PRP-ACP, PRP- BCT, and PC significantly increased cell viability of human tenocyte-like cells, whereas PC and AlloPL increased Col1A1 expression and PRP-BCT increased Col3A1 expression. MMP-1, IL-1β, and HGF expression was significantly increased and Scleraxis expression decreased by most blood products. COX1 expression significantly decreased by PC and AlloPL. No clear positive effects on tendon cell biology could be shown, which might partially explain the weak outcome results in clinical practice. Pooled PL seemed to have the most beneficial effects and might be the future in using blood products for tendon tissue regeneration.
Second language learning and identity: Cracking metaphors in ideological and poetic discourse in the third space
Creators: name: Yoshimoto, Mika
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Education, Language and Literature.
subject: Education, Bilingual and Multicultural.

description: This research study examines second language learning and identity construction through a hybrid design of case study and autoethnography. It argues for an elaborated understanding of the way that second language learners of English participate in the learning process in multiple contexts, in multiple discourses. From this perspective it considers the interdependence of language and identity in order to understand the experiences and difficulties of many second language learners. This research focuses on the identity struggles of Japanese women learning English as a second language from the perspective of sociocultural theory and critical theory in a postmodern stance. This framework allows me to consider how social identities are created discursively, how our conceptual metaphors function in Japanese and English, and how the process of participating in a new language and a new culture results in our living in neither culture but in hybrid spaces. Using autoethnography, I draw on my experiences as a Japanese woman learning English as a second language to understand what it means for a Japanese woman to be an English language learner as well as how English affects the identities of Japanese women. At the same time, the study also involves additional participants, namely three female Japanese students learning English in a Canadian University in Ontario. This hybrid design allows for a broader understanding of our everyday lives, languages, metaphors, and known and un-known selves as they take shape and transform. Using diary research, interviews and conversational group meetings, I examine how our individual and collective stories emerge. To do this I turn to four different discourse genres; narrative, haiku, metaphor and academic discourse. I choose to write narrative discourse to express our stories poetically. My decision to create was inspired by haiku, a genre that expresses my changing values and never-ending painful transformations. The untranslatable nature of language and this journey of women inspire haiku that emerges in a third space of the said and the unsaid. Finally, I turn to academic discourse to compose the meta-story of what I am doing and why, and to situate my identity and my research in a theoretical framework. The stories from the four of us contribute to a portrait of the tremendous ideological transformations involved in learning a second language. From the language of the research participants, we see how our conceptual system varies across cultures, implying multiple realities. This suggests that to promote cross-cultural understanding, we need to engage deeply with our experiences as they evoke the curriculum as lived.
Survival benefit of a low ratio of visceral to subcutaneous adipose tissue depends on LDL clearance versus production in sepsis
Creators: name: Lee, Joseph G. H.
name: Genga, Kelly R.
name: Pisitsak, Chawika
name: Boyd, John H.
name: Leung, Alex K. K.
name: Russell, James A.
name: Walley, Keith R. (Keith Robert)
Publisher: name: BioMed Central
Year: 2018

description: Background: Patients with sepsis with a high ratio of visceral adipose tissue (VAT) to subcutaneous adipose tissue (SAT) have increased mortality. Our goal was to investigate the mechanism of this effect, noting that low LDL levels are also associated with increased sepsis mortality. Accordingly we tested for association between VAT/SAT, low-density lipoprotein (LDL) levels, and mortality. Then we examined the effect of statin treatment, which decreases LDL production, and the effect of PCSK9 genotype, which increases LDL clearance. Methods: We performed retrospective analysis of a cohort of patients with sepsis from a tertiary care adult intensive care unit in Vancouver, Canada, who underwent abdominal computed tomography (CT) (n = 75) for clinical reasons. We compared LDL levels in patients with sepsis according to high versus low VAT/SAT and 90-day survival. We next examined the effects of statin therapy and PCSK9 loss-of-function genotype on survival. Results: Patients with a low VAT/SAT had increased 90-day survival and were relatively protected against low LDL levels in sepsis compared to high VAT/SAT. Statin treatment abrogated the beneficial effects of low VAT/SAT; eliminating the difference in LDL levels and survival between patients with low and high VAT/SAT. PSCK9 loss-of-function genotype similarly eliminated the increased LDL levels in low VAT/SAT patients but, in contrast, increased the survival advantage of low VAT/SAT compared to high VAT/SAT. Conclusions: Low LDL levels per se are not simply associated with decreased sepsis survival because lowering LDL levels by inhibiting LDL production (statin treatment) is associated with adverse outcomes, while increased LDL clearance (PCSK9 loss-of-function genotype) is associated with improved outcomes in patients with low VAT/SAT.
3874140.pdf
Creators: name: Ye, Yu
name: Liu, Fang
name: Wang, Mengxuan
name: Tai, Lixuan
name: Cui, Kaiyu
name: Feng, Xue
name: Zhang, Wei
name: Huang, Yidong
Publisher: name: Optica Publishing Group
Year: 2019
Subjects: Uncategorized

description: supplementary