title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð´Ð°ÑÑÐ¸ÐºÐ° Ð´Ð»Ñ Ð½ÐµÐ¸Ð½Ð²Ð°Ð·Ð¸Ð²Ð½Ð¾Ð³Ð¾ Ð¸Ð·Ð¼ÐµÑÐµÐ½Ð¸Ñ ÑÐºÐ¾ÑÐ¾ÑÑÐ¸ Ð¼Ð¸ÐºÑÐ¾ÑÐ¸ÑÐºÑÐ»ÑÑÐ¾ÑÐ½Ð¾Ð³Ð¾ ÐºÑÐ¾Ð²Ð¾ÑÐ¾ÐºÐ° Ð² ÐºÐ°Ð¿Ð¸Ð»Ð»ÑÑÐ°Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Development of an optical sensor for non-invasive measurement of thespeed of microcirculatory blood flow in capillaries.
Creators: name: Ð¡Ð°Ð·Ð¾Ð½Ð¾Ð²Ð°, ÐÐºÐ°ÑÐµÑÐ¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: ÑÐºÐ¾ÑÐ¾ÑÑÑ ÐºÑÐ¾Ð²Ð¾ÑÐ¾ÐºÐ°
ÑÐ¿ÐµÐºÐ»-ÐºÐ¾ÑÑÐµÐ»ÑÑÐ¸Ð¾Ð½Ð½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð·
Ð¼Ð¸ÐºÑÐ¾ÑÐ¸ÑÐºÑÐ»ÑÑÐ¸Ñ
Ð»Ð°Ð·ÐµÑÐ½Ð¾Ðµ Ð¸Ð·Ð»ÑÑÐµÐ½Ð¸Ðµ
ÐºÐ¾ÑÑÐµÐ»ÑÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÑÐ½ÐºÑÐ¸Ñ
ÑÑÐ¸ÑÑÐ¾ÑÐ¸ÑÑ
ÑÐ°ÑÑÐµÑÐ½Ð¸Ðµ
ÐºÑÐ¾Ð²Ð¾ÑÐ¾Ðº
blood flow velocity
speckle correlation analysis
microcirculation
laser radiation
correlation function
red blood cells
scattering
blood flow

description: Â  ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð´Ð°ÑÑÐ¸ÐºÐ° Ð´Ð»Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐºÐ¾ÑÐ¾ÑÑÐ¸ ÐºÑÐ¾Ð²Ð¾ÑÐ¾ÐºÐ° Ð² ÐºÐ°Ð¿Ð¸Ð»Ð»ÑÑÐ°Ñ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¼ÐµÑÐ¾Ð´Ð° ÑÐ¿ÐµÐºÐ»-ÐºÐ¾ÑÑÐµÐ»ÑÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð°. Ð¢Ð°Ðº ÐºÐ°Ðº ÐºÐ¾Ð¼Ð¼ÐµÑÑÐµÑÐºÐ¸Ðµ Ð¸ Ð»Ð°Ð±Ð¾ÑÐ°ÑÐ¾ÑÐ½ÑÐµ Ð¿ÑÐ¸Ð±Ð¾ÑÑ, ÑÐ¾Ð·Ð´Ð°Ð½Ð½ÑÐµ Ð´Ð»Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐºÐ¾ÑÐ¾ÑÑÐ¸ ÐºÑÐ¾Ð²Ð¾ÑÐ¾ÐºÐ°, Ð¸Ð¼ÐµÑÑ Ð½ÐµÐ´Ð¾ÑÑÐ°ÑÐºÐ¸, Ð·Ð°Ð´Ð°ÑÐ° ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð»Ð°Ð±Ð¾ÑÐ°ÑÐ¾ÑÐ½Ð¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¾Ð³Ð° ÑÐ²Ð»ÑÐµÑÑÑ Ð°ÐºÑÑÐ°Ð»ÑÐ½Ð¾Ð¹. Â  Ð ÑÐ¾Ð´Ðµ Ð¿ÑÐ¾ÐµÐºÑÐ° Ð±ÑÐ» ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½ Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð´Ð°ÑÑÐ¸Ðº, ÑÐ¾ÑÑÐ¾ÑÑÐ¸Ð¹ Ð¸Ð· Ð»Ð°Ð·ÐµÑÐ°, ÑÐ¾Ð±Ð¸ÑÐ°ÑÑÐµÐ¹ Ð»Ð¸Ð½Ð·Ñ, Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð²Ð¾Ð»Ð¾ÐºÐ½Ð°, ÑÐ¾ÑÐ¾Ð¿ÑÐ¸ÐµÐ¼Ð½Ð¸ÐºÐ° Ð¸ Ð°Ð½Ð°Ð»Ð¾Ð³Ð¾Ð²Ð¾-ÑÐ¸ÑÑÐ¾Ð²Ð¾Ð³Ð¾ Ð¿ÑÐµÐ¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°ÑÐµÐ»Ñ. Â  ÐÐ° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð½Ð¾Ð¼ Ð¿ÑÐ¸Ð±Ð¾ÑÐµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ñ ÑÐµÑÑÐ¾Ð²ÑÐµ Ð¸Ð·Ð¼ÐµÑÐµÐ½Ð¸Ñ Ð½Ð° ÑÑÐ»Ð¾Ð²Ð½Ð¾-Ð·Ð´Ð¾ÑÐ¾Ð²ÑÑ Ð²Ð¾Ð»Ð¾Ð½ÑÐµÑÐ°Ñ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð²Ð¾Ð·ÑÐ°ÑÑÐ½ÑÑ Ð³ÑÑÐ¿Ð¿, Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐºÐ¾ÑÐ¾ÑÑÐ¸ ÐºÑÐ¾Ð²Ð¾ÑÐ¾ÐºÐ° Ð¿ÑÐ¸ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ ÑÑÐ»Ð¾Ð²Ð¸ÑÑ, Ð° ÑÐ°ÐºÐ¶Ðµ Ð¸Ð·Ð¼ÐµÑÐµÐ½Ð¸Ñ Ð½Ð° Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐµ Ñ ÑÑÐ¾Ð½Ð¸ÑÐµÑÐºÐ¸Ð¼ Ð´Ð¸ÑÑÑÐ·Ð½ÑÐ¼ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸ÐµÐ¼ Ð¿ÐµÑÐµÐ½Ð¸. ÐÐ¾ Ð¿ÑÐ¸Ð²ÐµÐ´ÑÐ½Ð½ÑÐ¼ Ð² ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ°ÑÑÐ¸ ÑÐ¾ÑÐ¼ÑÐ»Ð°Ð¼ ÑÐ°ÑÑÑÐ¸ÑÐ°Ð½Ñ Ð²ÑÐµÐ¼Ñ ÐºÐ¾ÑÑÐµÐ»ÑÑÐ¸Ð¸ Ð¸ ÑÐºÐ¾ÑÐ¾ÑÑÑ ÐºÑÐ¾Ð²Ð¾ÑÐ¾ÐºÐ°, ÑÐ´ÐµÐ»Ð°Ð½ Ð²ÑÐ²Ð¾Ð´ Ð¾ ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐ¸Ð±Ð¾ÑÐ°. Â  ÐÐ¾Ð»ÑÑÐµÐ½Ð½ÑÐµ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð±ÑÐ»Ð¸ ÑÐ¾Ð¿Ð¾ÑÑÐ°Ð²Ð»ÐµÐ½Ñ ÑÐ¾ Ð·Ð½Ð°ÑÐµÐ½Ð¸ÑÐ¼Ð¸, Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð½ÑÐ¼Ð¸ Ð² Ð»Ð¸ÑÐµÑÐ°ÑÑÑÐµ Ð´Ð»Ñ Ð¾ÑÐµÐ½ÐºÐ¸ ÑÐ°Ð±Ð¾ÑÑ ÑÐ¾Ð·Ð´Ð°Ð½Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¸Ð±Ð¾ÑÐ° Ð¸ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÐ¸ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ ÐµÐ³Ð¾ Ð² Ð¼ÐµÐ´Ð¸ÑÐ¸Ð½ÑÐºÐ¸Ñ ÑÐµÐ½ÑÑÐ°Ñ. Â  ÐÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð»Ð¸ÑÑ Ð¾ÑÐºÑÑÑÑÐµ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½ÑÐµ ÑÐµÑÑÑÑÑ Ð¸ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ñ Ð¿Ð¾Ð¸ÑÐºÐ° Ð¸ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¸. ÐÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¾ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð¾Ðµ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ðµ Excel Ð¸ Python.
description: Â  This work is devoted to the creation of an optical sensor for studying the speed of blood flow in capillaries based on the speckle correlation analysis method. Since commercial and laboratory instruments designed to study blood flow velocity have disadvantages, the task of creating a laboratory analogue is urgent. Â  The project developed an optical sensor consisting of a laser, a collecting lens, an optical fiber, a photodetector and an analog-to-digital converter. Â  Using the developed device, test measurements were carried out on relatively healthy volunteers of various age groups, studies of blood flow velocity under various conditions, as well as measurements on a patient with chronic diffuse liver disease. Using the formulas given in the theoretical part, the correlation time and blood flow speed were calculated, and a conclusion was drawn about the operation of the device. Â  The results obtained were compared with the values presented in the literature to evaluate the performance of the created device and the possibility of using it in medical centers. Â  Open educational resources and information search and analysis programs were used. The Excel and Python software has been applied.