cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Integrated virtual screening and molecular dynamics simulation approaches revealed potential natural inhibitors for DNMT1 as therapeutic solution for triple negative breast cancer
Creators: name: Bashir, Yasir
name: Noor, Fatima
name: Ahmad, Sajjad
name: Tariq, Muhammad Hamza
name: Qasim, Muhammad
name: Qamar, Muhammad Tahir ul
name: Almatroudi, Ahmad
name: Allemailem, Khaled S.
name: Alrumaihi, Faris
name: Alshehri, Faez Falah
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Biochemistry
Space Science
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer

description: Triple negative breast cancers (TNBC) are clinically heterogeneous but mostly aggressive malignancies devoid of expression of the estrogen, progesterone, and HER2 (ERBB2 or NEU) receptors. It accounts for 15–20% of all cases. Altered epigenetic regulation including DNA hypermethylation by DNA methyltransferase 1 (DNMT1) has been implicated as one of the causes of TNBC tumorigenesis. The antitumor effect of DNMT1 has also been explored in TNBC that currently lacks targeted therapies. However, the actual treatment for TNBC is yet to be discovered. This study is attributed to the identification of novel drug targets against TNBC. A comprehensive docking and simulation analysis was performed to optimize promising new compounds by estimating their binding affinity to the target protein. Molecular dynamics simulation of 500 ns well complemented the binding affinity of the compound and revealed strong stability of predicted compounds at the docked site. Calculation of binding free energies using MMPBSA and MMGBSA validated the strong binding affinity between compound and binding pockets of DNMT1. In a nutshell, our study uncovered that Beta-Mangostin, Gancaonin Z, 5-hydroxysophoranone, Sophoraflavanone L, and Dorsmanin H showed maximum binding affinity with the active sites of DNMT1. Furthermore, all of these compounds depict maximum drug-like properties. Therefore, the proposed compounds can be a potential candidate for patients with TNBC, but, experimental validation is needed to ensure their safety. Communicated by Ramaswamy H. Sarma
Φιλοσοφικό Συμπόσιο Πλατωνικής Φιλοσοφίας
Creators: name: Νιάρχος, Κωνσταντίνος
Publisher: name: Ελληνική Φιλοσοφική Επιθεώρηση
Year: 2012
Subjects: philosophy

description: Ελληνική Φιλοσοφική Επιθεώρηση, Vol 2, No 6 (1985)
Ευρωπαϊκό Συνέδριο Φιλοσοφίας: Ό άνθρωπος στον αιώνα της τεχνολογίας
Creators: name: Βουδούρης, Κωνσταντίνος
name: Δημητράκος, Δημήτρης
Publisher: name: Ελληνική Φιλοσοφική Επιθεώρηση
Year: 2012
Subjects: philosophy

description: Ελληνική Φιλοσοφική Επιθεώρηση, Vol 2, No 6 (1985)
Nine Million Book Items and Eleven Million Citations: A Study of Book-Based Scholarly Communication Using OpenCitations
Creators: name: Zhu, Yongjun
name: Yan, Erjia
name: Peroni, Silvio
name: Che, Chao
Publisher: name: arXiv
Year: 2019
Subjects: subject: Digital Libraries (cs.DL)
subject: FOS: Computer and information sciences

description: Books have been widely used to share information and contribute to human knowledge. However, the quantitative use of books as a method of scholarly communication is relatively unexamined compared to journal articles and conference papers. This study uses the COCI dataset (a comprehensive open citation dataset provided by OpenCitations) to explore books' roles in scholarly communication. The COCI data we analyzed includes 445,826,118 citations from 46,534,705 bibliographic entities. By analyzing such a large amount of data, we provide a thorough, multifaceted understanding of books. Among the investigated factors are 1) temporal changes to book citations; 2) book citation distributions; 3) years to citation peak; 4) citation half-life; and 5) characteristics of the most-cited books. Results show that books have received less than 4% of total citations, and have been cited mainly by journal articles. Moreover, 97.96% of books have been cited fewer than ten times. Books take longer than other bibliographic materials to reach peak citation levels, yet are cited for the same duration as journal articles. Most-cited books tend to cover general (yet essential) topics, theories, and technological concepts in mathematics and statistics.
Martin Heidegger's account of the nature of man
Creators: name: Small, Robin
Publisher: name: The Australian National University
Year: 1974

description: This thesis is a study of some major aspects of Martin Heidegger's conception of the nature of man. Central attention is given to Heidegger's major work, Sein und Zeit (1927). In the opening chapters, the context within which the theories presented in this work are to be understood is fixed through successive examinations of some important philosophical concepts. The first chapter looks into the notion of philosophical anthropology, and analyses Heidegger's attitude towards this philosophical discipline and towards the question "What is man?". In the second chapter Heidegger's description of his philosophy as an ontology is discussed, and it is argued that he can appropriately be seen as a thinker standing in the Kantian tradition of transcendental philosophy. In the next chapter Heidegger's links with the existential philosophy of Kierkegaard are discussed, and a general perspective is suggested for an understanding of the tasks of Heidegger's theory of human existence: it is the idea that Heidegger is attempting to present a 'this-worldly' philosophy which nevertheless preserves themes originating in a dualistic and religious mode of thought. The fourth chapter treats a number of aspects of the relationship between Heidegger and his phenomenological predecessor, Edmund Husserl. The problem of reconciling the existential and the ontological aspects of Sein und Zeit is explored here. The next two chapters are designed to supply a basic outline of Heidegger's conception of human existence, setting out the possible interpretations of his notion of existential possibility, and then moving on to look into the distinction between the authentic and inauthentic modes of existence. The seventh, eighth and ninth chapters focus on particular elements within Heidegger's general theory of the human being: the notions of temporality and of Being-towardsdeath, and the question of interpersonal relations. These last two are treated as 'test cases' for judging the adequacy of the Heideggerian concept of human existence. On the one hand, it is seen that Heidegger is prevented from offering any plausible account of the interpersonal sphere by his own fundamental assumptions. On the other hand, however, his theory of Beingtowards-death is defended against the criticisms of a number of his interpreters, and it is argued that this theory provides insights which are lacking in the traditional conception of human mortality. The difference between these findings suggests that it may be impossible to construct a theory of human existence which will be equally adequate to every aspect of the human being.
Perapion fallax
Creators: name: Morris, Michael G.
name: Sw, London
name: Dt, Dorset
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Apionidae
Perapion
Perapion fallax

description: Perapion fallax (Wollaston, 1864)
(Fig. 1)
 WOLLASTON (1864) described this species under the name fallax. The replacement name supplied by WARNER (1958) (neofallax) is unjustified. Wollaston commented on the species’ similarity to the common European P. violaceum (Kirby, 1808), and BRITO & OROMÍ (1986) tabulated the differences between the two species. Like P. violaceum, P. fallax feeds as a larva in the stems of Rumex (Rumex) spp. (‘docks’). BRITO & OROMÍ (1986) recorded it from R. lunaria (Tree Sorrel), but I have found it on that very common Canarian plant only in Gran Canaria (in January 2004 at two sites) and in Lanzarote (in January 2005, also at two sites); it is possible that R. lunaria is only palatable as a host of the adults when its foliage is fresh and tender. Perapion neofallax occurred in some numbers on R. conglomeratus in Tenerife (March 2001) and La Palma (February 1998) and in both islands it also occurred on Emex spinosa. Larvae were found in stems of the latter plant in the Orotava Valley in March 1993. Perapion fallax has been recorded from all the islands; MACHADO & OROMÍ (2000) omitted it from La Gomera, but BRITO & OROMÍ (1986) included the record of a single example taken there by Lindberg. It is not restricted to the Canary Islands but has been found in North Africa and southern Spain (M. A. Alonso-Zarazaga, pers. comm.).
Wollaston’s BMNH collection contains 4 male and 4 female specimens, from La Palma, Tenerife, Gran Canaria and Lanzarote. The example labelled ‘Type’ is a male and colourcoded for Lanzarote. 5 males and 4 females are in the OUMNH collection, from El Hierro, La Palma, Tenerife, Lanzarote and possibly Gran Canaria.
description: Published as part of Morris, Michael G., Sw, London & Dt, Dorset, 2011, The Apionidae (Coleoptera) of the Canary Islands, with particular reference to the contribution of T. Vernon Wollaston, pp. 157-182 in Acta Entomologica Musei Nationalis Pragae 51 (1) on pages 165-166, DOI: 10.5281/zenodo.5327310
Baryonic contributions to the dilepton spectrum of nucleon-nucleon collisions
Creators: name: Zetenyi, M.
name: Wolf, Gy.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study the production of dileptons in relativistic nucleon-nucleon collisions. Additionally to the traditional dilepton production channels (vector meson decays, meson and Delta(1232) Dalitz decays) we included in our model as new dilepton sources the Dalitz decay of higher unflavored baryon resonances with spin<=5/2 and mass<=2.25 GeV/c^2. The contributions of these new channels are estimated using experimental information about the Ngamma decays of the resonances and have large uncertainties. The obtained dilepton spectra are compared to the experimental data by the DLS collaboration. Predictions for the HADES detector (SIS, GSI) are also discussed. In spite of the large uncertainties of the higher resonance Dalitz decay contributions we are able to draw the conclusion that these contributions are negligible compared to the other dilepton sources and do not influence the detectability of the phi and omega vector meson peaks.
description: 9 pages, 4 figures, version accepted for publication in Phys. Rev. C
Synopeas bifoveatum
Creators: name: Madl, Michael
name: H, Inostemma
name: F, Leptacis
name: L, Platygaster
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Platygastridae
Synopeas
Synopeas bifoveatum

description: Synopeas bifoveatum (KIEFFER, 1912)
 Amblyaspis bifoveatus nov.sp.: KIEFFER 1912: 78 (key), 79 (descr. ♀, Seychelles).
 Synopeas bifoveatus (KIEFFER, 1912): KIEFFER 1926: 668 (key), 689 (tax., descr. ♀, Seychelles). Synopeas bifoveatus (KIEFFER, 1912): MASNER 1960: 2 (tax.).
 Synopeas bifoveatus (KIEFFER, 1912): MASNER 1965: 140 (tax., Seychelles).
 Synopeas bifoveatus (KIEFFER, 1912): VLUG 1995: 76 (cat.).
 Synopeas bifoveatus (KIEFFER, 1912): SUNDHOLM 1970: 388 (cat.).
 Synopeas bifoveatus (KIEFFER, 1912): BUHL 2011: 108 (tax.).
 Synopeas bifoveatus (KIEFFER, 1912): MADL 2013: 237 (cat. Seychelles).
 Synopeas bifoveatus (KIEFFER, 1912): GERLACH 2013: 366 (red list Seychelles).
D i s t r i b u t i o n: Seychelles: Inner Seychelles (Mahé).
Endemic.
description: Published as part of Madl, Michael, H, Inostemma, F, Leptacis & L, Platygaster, 2016, A catalogue of the family Platygastridae (Platygastroidea) of the Malagasy subregion. Part I: Subfamilies Platygastrinae and Sceliotrachelinae (Insecta: Hymenoptera), pp. 55-69 in Linzer biologische Beiträge 48 (1) on page 64, DOI: 10.5281/zenodo.5417040
Experimental investigation of quantum decay at short, intermediate and long times via integrated photonics
Creators: name: Crespi, Andrea
name: Pepe, Francesco V.
name: Facchi, Paolo
name: Sciarrino, Fabio
name: Mataloni, Paolo
name: Nakazato, Hiromichi
name: Pascazio, Saverio
name: Osellame, Roberto
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The decay of an unstable system is usually described by an exponential law. Quantum mechanics predicts strong deviations of the survival probability from the exponential: indeed, the decay is initially quadratic, while at very large times it follows a power law, with superimposed oscillations. The latter regime is particularly elusive and difficult to observe. Here we employ arrays of single-mode optical waveguides, fabricated by femtosecond laser direct inscription, to implement quantum systems where a discrete state is coupled and can decay into a continuum. The optical modes correspond to distinct quantum states of the photon and the temporal evolution of the quantum system is mapped into the spatial propagation coordinate. By injecting coherent light states in the fabricated photonic structures and by measuring light with an unprecedented dynamic range, we are able to experimentally observe not only the exponential decay regime, but also the quadratic Zeno region and the power-law decay at long evolution times.
Δωδέκατο Παγκόσμιο Συνέδριο Κοινωνικής Φιλοσοφίας και Φιλοσοφίας του Δικαίου
Creators: name: Χάνος, Αντώνης
Publisher: name: Ελληνική Φιλοσοφική Επιθεώρηση
Year: 2012
Subjects: philosophy

description: Ελληνική Φιλοσοφική Επιθεώρηση, Vol 2, No 6 (1985)
The LIGO Interferometer Sensing and Control System
Creators: name: Heefner, J.
name: Bork, R.
name: Abbott, R.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: General Physics (physics.gen-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The LIGO Interferometer Sensing and Control System (ISC) is a large and highly distributed Multiple Input Multiple Output (MIMO) control system that is used to control the length and alignment degrees of freedom of the interferometers. The 4 kilometer Fabry-Perot cavity lengths are controlled to better than 10-13 meters (rms) and the angular degrees of freedom are controlled to better than 10-8 radians. This paper will describe the real-time digital servo control systems that have been designed, developed and implemented for the LIGO Length Sensing and Control (LSC) [1] and Alignment Sensing and Control (ASC) [2] systems. In addition, the paper will describe how these controls, along with the suspended optic controls [3], have been integrated into the overall LIGO control and data acquisition system [4].
description: 3 Pages, 2001 ICALEPCS conference
Τρίτο Πανελλήνιο Συνέδριο Φιλοσοφίας
Creators: name: -, -
Publisher: name: Ελληνική Φιλοσοφική Επιθεώρηση
Year: 2012
Subjects: philosophy

description: Ελληνική Φιλοσοφική Επιθεώρηση, Vol 3, No 9 (1986)
A guided Monte Carlo method for optimization problems
Creators: name: Li, S. P.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: We introduce a new Monte Carlo method by incorporating a guided distribution function to the conventional Monte Carlo method. In this way, the efficiency of Monte Carlo methods is drastically improved. To further speed up the algorithm, we include two more ingredients into the algorithm. First, we freeze the sub-patterns that have high probability of appearance during the search for optimal solution, resulting in a reduction of the phase space of the problem. Second, we perform the simulation at a temperature which is within the optimal temperature range of the optimization search in our algorithm. We use this algorithm to search for the optimal path of the traveling salesman problem and the ground state energy of the spin glass model and demonstrate that its performance is comparable with more elaborate and heuristic methods.
description: 4 pages, ReVTeX
Major chemical constituents and antioxidant activities of different extracts from the peduncles of Hovenia acerba Lindl
Creators: name: Peng, Han
name: Deng, Zeyuan
name: Chen, Xuan
name: Sun, Yong
name: Zhang, Bing
name: Li, Hongyan
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Plant Biology

description: Hovenia acerba Lindl. is a perennial tree of Rhamnaceae family. In the present study, four solvents (80% methanol, ethyl acetate, n-hexane, and water) were used to extract the compounds of Hovenia acerba Lindl. peduncles (HAP). The total contents of phenolics and tannins (TPC and TTC), as well as their antioxidant activities (DPPH, ABTS, and FRAP) of these four different extracts including 80% methanol extract (ME), ethyl acetate extract (EE), n-hexane extract (HE) and water extract (WE) were compared. The antioxidant activities of HAP showed positive correlations with TPC and TTC, indicating that phenolics maybe a major contributor to the antioxidant activities of HAP. The significant difference between antioxidant activities and TPC/TTC implied the respective contribution extent of phenolics for the antioxidant activities of four solvent extracts. Besides, a total of 117 compounds, including 7 oligosaccharides, 11 organic acids, 41 phenolics, 1 steroids, 25 terpenes, 11 fatty acids, 9 amino acids, and 12 other compounds were identified or tentatively characterized in HAP for the first time. Among them, 23 bioactive constituents, including 4 organic acids, 5 phenolic acids, and 14 flavonoids, were quantified. The comparison of characterization and quantitation of 4 extracts demonstrated that 80% methanol showed the widest range of selectivity for both HAP flavonoid aglycones and glycosides, while ethyl acetate preferred to extract the flavonoids aglycone from HAP. Secondly, water and 80% methanol were excellent solvents for the extraction of phenolic acids. And both ethyl acetate and 80% methanol perform well at the extraction of terpenes and steroids.
Implementation of Islamic Work Values in Realizing Sharia Good Corporate Governance and Its Implications in Stakeholders Oriented Values (SOV) and Financial Performance of Islamic Banking in Indonesia
Creators: name: Hamdani Hamdani
name: Yuswar Zainul Basri
name: Khomsiyah Khomsiyah
name: Syarif Surbakti
Publisher: name: figshare
Year: 2019
Subjects: subject: 130203 Economics, Business and Management Curriculum and Pedagogy
subject: FOS: Educational sciences

description: This research examines the effect of Islamic work values on sharia good corporate governance (GCG), and its implications for stakeholders oriented values (SOV) and Islamic banking financial performance in Indonesia. The method of analysis uses Structural Equation Modeling (SEM) with a partial least square (PLS) test. The sample of this study is Islamic banking with an analysis unit of 8 Islamic Commercial Banks in Indonesia. The sampling technique uses a sampling method randomly. The results of the study show that Islamic work values positively influence SOV. Likewise, Islamic work values have a positive effect on sharia GCG. While Islamic work values have no positive effect on sharia GCG and have no implications for SOV. Likewise, Islamic work values do not have a positive effect on financial performance. While Islamic work values have a positive and significant effect on sharia GCG and have implications for financial performance. Islamic work values, combined with sharia GCG, are still oriented to shareholders. For Islamic banking, the GCG model adopted in Indonesia refers to the Continental European model, which is still oriented to shareholders. High moral commitment is needed to implement Islamic work values and Islamic GCG so that it can have implications for the interests of stakeholders. For regulators, GCG reforms need to consider specific business, legal, and social societies so that the objectives of sharia GCG can be achieved optimally.
Velocity bias and the nonlinear perturbation theory of peaks
Creators: name: Matsubara, Takahiko
Publisher: name: arXiv
Year: 2019
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The biasing in the large-scale structure of the universe is a crucial problem in cosmological applications. The peaks model of biasing predicts a linear velocity bias of halos, which is not present in a simple model of local bias. We investigate the origin of the velocity bias in the peaks model from the viewpoint of the integrated perturbation theory, which is a nonlinear perturbation theory in the presence of general Lagrangian bias. The presence of the velocity bias in the peaks model is a consequence of the "flat constraint," ${\nabla}δ= 0$; i.e., all the first spatial derivatives should vanish at the locations of peaks. We show that the velocity bias in the peaks model is systematically derived in the framework of the integrated perturbation theory, and then develop a formal theory to perturbatively trace the nonlinear evolution of biased objects with the flat constraint. A formula for the nonlinear velocity dispersion of peaks with the one-loop approximation is also derived.
description: 18 pages, 9 figures, Published in PRD
Degeneracies when T=0 Two Body Interacting Matrix Elements are Set Equal to Zero : Talmi's method of calculating coefficients of fractional parentage to states forbidden by the Pauli principle
Creators: name: Robinson, Shadow J. Q.
name: Zamick, Larry
Publisher: name: arXiv
Year: 2001
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: In a previous work we studied the effects of setting all two body T=0 matrix elements to zero in shell model calculations for $^{43}$Ti ($^{43}$Sc) and $^{44}$Ti. The results for $^{44}$Ti were surprisingly good despite the severity of this approximation. In this approximation degeneracies arose in the T=1/2 I=$({1/2})^-_1$ and $({13/2})^-_1$ states in $^{43}$Sc and the T=1/2 $I=({13/2})_2^-$, $({17/2})^-_1$, and $({19/2})_1^-$ in $^{43}$Sc. The T=0 $3_2^+$, $7_2^+$, $9_1^+$, and $10_1^+$ states in $^{44}$Ti were degenerate as well. The degeneracies can be explained by certain 6j symbols and 9j symbols either vanishing or being equal as indeed they are. Previously we used Regge symmetries of 6j symbols to explain these degeneracies. In this work a simpler more physical method is used. This is Talmi's method of calculating coefficients of fractional parentage for identical particles to states which are forbidden by the Pauli principle. This is done for both one particle cfp to handle 6j symbols and two particle cfp to handle 9j symbols. The states can be classified by the dual quantum numbers ($J_π,J_ν$).
A study of supply response of rubber in Sri Lanka
Creators: name: Herath, Herath Mudiyanselage Gamini
Publisher: name: Canberra, ACT : The Australian National University
Year: 1975
Subjects: subject: Rubber industry and trade Sri Lanka

description: The rubber industry occupies an important place in the Sri Lanka economy. The recent performance of the industry both in respect of replanting and processing and the deteriorating position of rubber in world trade has caused great concern. The need to improve replanting, production and processing is recognised by the Government. To this end a rubber replanting subsidy and some processing facilities are provided. The results have not been encouraging. This study attempts an estimate of the replanting and output response of rubber producers. The main determinants of replanting such as profitability and the replanting subsidy are specified and discussed. These are investigated for three different producer groups namely - smallholders, medium estates and large estates. The determinants of output are also investigated. Several hypothesis are formulated in respect of output response, It is seen that profitability as determined by costs and prices has been the only important determinant of replanting by all three producer groups These groups are shown to have been efficient in an allocative sense. The recent decline in profitability is the reason for the decline of replanting of all groups, despite the replanting subsidy. Price is not found to be an important determinant of output in this study. However it is argued that price could be an important determinant of output. It is shown that the obscure role of price has been due to high yielding varieties coming into production.
Synopeas popovicii BUHL 2015
Creators: name: Madl, Michael
name: H, Inostemma
name: F, Leptacis
name: L, Platygaster
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Platygastridae
Synopeas
Synopeas popovicii

description: Synopeas popovicii BUHL, 2015
 Synopeas popovicii nov.sp.: BUHL 2015: 327 (descr. ♀, biol., Madagascar), 331 (figs 36-38).
D i s t r i b u t i o n: Madagascar: Prov. Toamasina: Andasibe.
Endemic.
description: Published as part of Madl, Michael, H, Inostemma, F, Leptacis & L, Platygaster, 2016, A catalogue of the family Platygastridae (Platygastroidea) of the Malagasy subregion. Part I: Subfamilies Platygastrinae and Sceliotrachelinae (Insecta: Hymenoptera), pp. 55-69 in Linzer biologische Beiträge 48 (1) on page 64, DOI: 10.5281/zenodo.5417040
Autoregressive Model with Spatial Dependence and Missing Data
Creators: name: Zhou, Jing
name: Liu, Jin
name: Wang, Feifei
name: Wang, Hansheng
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: We study herein an autoregressive model with spatially correlated error terms and missing data. A logistic regression model with completely observed covariates is used to model the missingness mechanism. An autoregressive model is used to accommodate time series dependence, and a spatial error model is used to capture spatial dependence. To estimate the model, a weighted least squares estimator (WLSE) is developed for the temporal component, and a weighted maximum likelihood estimator (WMLE) is developed for the spatial component. The asymptotic properties for both estimators are investigated. The finite sample performance is assessed through extensive simulation studies. A real data example about Beijing’s PM2.5 level data is illustrated.
Τρίτο Διεθνές Συμπόσιο Φιλοσοφίας
Creators: name: -, -
Publisher: name: Ελληνική Φιλοσοφική Επιθεώρηση
Year: 2012
Subjects: philosophy

description: Ελληνική Φιλοσοφική Επιθεώρηση, Vol 3, No 9 (1986)
What Drives Government Security Yields in Developing Countries? Evidence from the Countries in the West African Economic and Monetary Union (WAEMU)
Creators: name: Issoufou Soumaila
Publisher: name: figshare
Year: 2019
Subjects: subject: 130203 Economics, Business and Management Curriculum and Pedagogy
subject: FOS: Educational sciences

description: The purpose of this study is to analyze the determinants of government security yields in relation to the recent development of WAEMU government securities market. The determinants are grouped into three categories of factors; namely macroeconomic factors, microstructure factors, and the external factors. The results show that economic growth rate, as well as countries capacity to effectively organize government securities issuances, are the main drivers of government securities yields. The policy implication of the study is that WAEMU countries should monitor their economic performance and implement structural reforms in order to maintain sustained economic growth.
Διαλέξεις-Ανακοινώσεις-Εκδηλώσεις
Creators: name: -, -
Publisher: name: Ελληνική Φιλοσοφική Επιθεώρηση
Year: 2012
Subjects: philosophy

description: Ελληνική Φιλοσοφική Επιθεώρηση, Vol 3, No 9 (1986)
Callosides Howden. Unfortunately 1971
Creators: name: Howden, H. F.
Publisher: name: Zenodo
Year: 2001
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Hybosoridae
Callosides

description: Key to Species of Callosides
1 Pronotum with four obvious, large tubercles; head with two longitudinal swellings -------------------------------------------------------------------------------------------------------------------------- 2
 1' Pronotum with two, small, lateral tubercles; head unevenly convex; male genitalia as in Figures 8, 9; Valle del Cauca, Colombia ----------------------------------- ---------------------------------------------------------------------------------------------------------------------------- C. campbelli Howden
 2 Elytral disc between suture and lateral carina with two irregular rows of small tubercles, tubercles on apical declivity rounded, sides not abruptly elevated; male genitalia as in Figures 6, 7; Carchı´, Ecuador ----------------------- ----------------------------------------------------------------------------------------------------------------------------------------- C. genieri n. sp.
 2' Elytral disc between suture and lateral carina lacking rows of tubercles, tubercles on apical declivity abruptly elevated; genitalia as in Figures 10, 11; Napo, Ecuador ------------------------------- C. bartolozzii Paulian and Cambefort
description: Published as part of Howden, H. F., 2001, A New Tribe Of Hybosorinae With A Description Of A New Species Of Callosides Howden (Coleoptera: Scarabaeidae), pp. 199-204 in The Coleopterists Bulletin 55 (2) on pages 202-203, DOI: 10.1649/0010-065X(2001)055[0199:ANTOHW]2.0.CO;2, http://zenodo.org/record/10102738
HOTLink Rack Monitor
Creators: name: Franck, A. R.
name: Goodwin, R. W.
name: Kasley, P. A.
name: Shea, M. F.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: A remote data acquisition chassis, called a HOTLink Rack Monitor, HRM, has been developed for use in the Fermilab control system. This chassis provides for 64 analog input channels, 8 analog output channels, and 8 bytes of digital I/O. The interface to the host VMEbus crate is by way of a 320 MHz HOTLink serial connection to a PMC mezzanine module. With no processor intervention, all data sources in the remote chassis are read at 100 microsec intervals, timestamped, and stored in a 2 MB circular buffer on the PMC module. In operation, the memory always contains the most recent 16k samples of 10 kHz data from all 64 analog input channels. An expansion module that resides in the HRM chassis records snapshot data for 8 analog channels, each channel consisting of up to 16k readings, digitized at rates up to 10 MHz. Snapshot data is also returned and stored in buffers on the PMC module. Because the HRM presents a memory-mapped interface to the host, it is independent of the operating system and may be used in any system that supports PMC mezzanine modules.
description: 3 pages, ICALEPCS-2001
Fitting the Strong Coupling Constant with Soft-Drop Thrust
Creators: name: Marzani, Simone
name: Reichelt, Daniel
name: Schumann, Steffen
name: Soyez, Gregory
name: Theeuwes, Vincent
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Soft drop has been shown to reduce hadronisation effects at $e^+e^-$ colliders for the thrust event shape. In this context, we perform fits of the strong coupling constant for the soft-drop thrust distribution at NLO+NLL accuracy to pseudo data generated by the \textsf{Sherpa}~event generator. In particular, we focus on the impact of hadronisation corrections, which we estimate both with an analytical model and a Monte-Carlo based one, on the fitted value of $α_s(m_Z)$. We find that grooming can reduce the size of the shift in the fitted value of $α_s$ due to hadronisation. In addition, we also explore the possibility of extending the fitting range down to significantly lower values of (one minus) thrust. Here, soft drop is shown to play a crucial role, allowing us to maintain good fit qualities and stable values of the fitted strong coupling. The results of these studies show that soft-drop thrust is a promising candidate for fitting $α_s$ at $e^+ e^-$ colliders with reduced impact of hadronisation effects.
description: 39 pages, 13 figures; Published version, clarified treatment of hadronisation effects
Synopeas rajaonarimampianinai BUHL 2015
Creators: name: Madl, Michael
name: H, Inostemma
name: F, Leptacis
name: L, Platygaster
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Platygastridae
Synopeas
Synopeas rajaonarimampianinai

description: Synopeas rajaonarimampianinai BUHL, 2015
 Synopeas rajaonarimampianinai nov.sp.: BUHL 2015: 328 (descr. ♀, biol., Madagascar), 331 (figs 39, 40).
D i s t r i b u t i o n: Madagascar: Prov. Toamasina: Andasibe.
Endemic.
description: Published as part of Madl, Michael, H, Inostemma, F, Leptacis & L, Platygaster, 2016, A catalogue of the family Platygastridae (Platygastroidea) of the Malagasy subregion. Part I: Subfamilies Platygastrinae and Sceliotrachelinae (Insecta: Hymenoptera), pp. 55-69 in Linzer biologische Beiträge 48 (1) on page 64, DOI: 10.5281/zenodo.5417040
Additional file 6 of Cross talk between RNA modification writers and tumor development as a basis for guiding personalized therapy of gastric cancer
Creators: name: Zhang, Shi
name: Kuang, Guanghao
name: Huang, Yao
name: Huang, Xinxin
name: Wang, Weiyu
name: Wang, Guoqiang
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 6: Fig. S6. Functional analysis of 194 RNA modification related genes and survival analysis of 300 samples in GSE62254 dataset. (A-C) GO analysis of 194 genes on molecular function (A), cellular component (B) and biological process (C). (D) Kaplan-Meier survival curve of cluster A and cluster B in GSE62254 dataset. Log-rank test was performed.
title: Working Together: Managing Social Capital to Facilitate an Organisational Climate for Innovativeness in an Acute Health Service Context
Creators: name: Black, Helen Patricia
Publisher: name: Griffith University
Year: 2015
Subjects: subject: Acute health service
subject: Innovation in health service provision
subject: Social capital
subject: Operating theatre environments

description: This research addresses the need to consider the organisational context and climate in the innovation process in an acute health service context. A critical review of the literature indicates an overlap exists between social capital and an organisational climate for innovativeness; however, the literature is underdeveloped in addressing the relationships between social capital and organisational climate explicitly. Exploring how social capital evolves offers a new perspective to management of change and innovativeness in a dynamic and socially complex environment such as operating theatre suites. The social capital and organisational climate for innovativeness literature is scarce in the context of health services. Health services in Australia and elsewhere are under constant pressure to increase throughput of patients and improve efficiencies, particularly in the area of surgical intervention. Many change initiatives are designed with standardised implementation without regard for the influences of the organisational context in the process (Greenhalgh et al., 2005, Greenhalgh et al., 2004). Therefore, acute health services, and in particular operating theatre environments, are rich sites to explore the influence of organisational climate on innovativeness. This research uses a sequential mixed methods approach to explore the relationship between social capital and organisational climate for innovativeness in three differently sized operating theatre suites in New South Wales (NSW), Australia. The differences in operating theatre suite size provided an opportunity to explore the impact of size in relation to eight organisational climate dimensions, in accordance with the survey initially employed by Garcia-Goni, Maroto, and Rubalcaba (2007).
Structural insights into the mechanism of resistance to bicalutamide by the clinical mutations in androgen receptor in chemo-treatment resistant prostate cancer
Creators: name: Majeed, Abdul
name: Qamar, Muhammad Tahir ul
name: Maryam, Arooma
name: Mirza, Muhammad Usman
name: Alhussain, Laila
name: Al Otaibi, Seham Obaid
name: Almatroudi, Ahmad
name: Allemailem, Khaled S.
name: Alrumaihi, Faris
name: Aloliqi, Abdulaziz A.
name: Alshehri, Faez Falah
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Despite advanced diagnosis and detection technologies, prostate cancer (PCa) is the most prevalent neoplasms in males. Dysregulation of the androgen receptor (AR) is centrally involved in the tumorigenesis of PCa cells. Acquisition of drug resistance due to modifications in AR leads to therapeutic failure and relapse in PCa. An overhaul of comprehensive catalogues of cancer-causing mutations and their juxta positioning on 3D protein can help in guiding the exploration of small drug molecules. Among several well-studied PCa-specific mutations, T877A, T877S and H874Y are the most common substitutions in the ligand-binding domain (LBD) of the AR. In this study, we combined structure as well as dynamics-based in silico approaches to infer the mechanistic effect of amino acid substitutions on the structural stability of LBD. Molecular dynamics simulations allowed us to unveil a possible drug resistance mechanism that acts through structural alteration and changes in the molecular motions of LBD. Our findings suggest that the resistance to bicalutamide is partially due to increased flexibility in the H12 helix, which disturbs the compactness, thereby reducing the affinity for bicalutamide. In conclusion, the current study helps in understanding the structural changes caused by mutations and could assist in the drug development process. Communicated by Ramaswamy H. Sarma
From Planck area to graph theory: Topologically distinct black hole microstates
Creators: name: Davidson, Aharon
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We postulate a Planck scale horizon unit area, with no bits of information locally attached to it, connected but otherwise of free form, and let $n$ such geometric units compactly tile the black hole horizon. Associated with each topologically distinct tiling configuration is then a simple, connected, undirected, unlabeled, planar, chordal graph. The asymptotic enumeration of the corresponding integer sequence gives rise to the Bekenstein-Hawking area entropy formula, automatically accompanied by a proper logarithmic term, and fixes the size of the horizon unit area, thereby constituting a global realization of Wheeler's "it from bit" phrase. Invoking Polya's theorem, an exact number theoretical entropy spectrum is offered for the 2+1 dimensional quantum black hole.
description: 6 pages, 5 figures; v2: minor changes, ref added; v3: version published in PRD (RC)
Synopeas seychellensis
Creators: name: Madl, Michael
name: H, Inostemma
name: F, Leptacis
name: L, Platygaster
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Platygastridae
Synopeas
Synopeas seychellensis

description: Synopeas seychellensis (KIEFFER, 1912)
 Platygaster seychellensis nov.sp.: KIEFFER 1912: 79 (key, descr. ♀, Seychelles).
 Platygaster seychellensis KIEFFER, 1912: KIEFFER 1926: 768 (key), 832 (tax., descr. ♀ Seychelles).
 Platygaster seychellensis KIEFFER, 1912: RISBEC 1950: 619 (key).
 Platygaster seychellensis KIEFFER, 1912: RISBEC 1955: 110 (key).
 Synopeas seychellensis (KIEFFER, 1912): MASNER 1965: 142 (tax., Seychelles).
 Platygaster seychellensis KIEFFER, 1912: SUNDHOLM 1970: 394 (cat.).
 Synopeas seychellensis (KIEFFER, 1912): VLUG 1995: 82 (cat.).
 Platygaster seychellensis KIEFFER, 1912: GERLACH, MATYOT & SAARISTO 1997: 28 (cat. Seychelles (Silhouette)).
 Synopeas seychellensis (KIEFFER, 1912): VLUG 2011: 110 (key).
 Synopeas seychellensis (KIEFFER, 1912): MADL 2013: 237 (cat. Seychelles).
 Synopeas seychellensis (KIEFFER, 1912): GERLACH 2013: 366 (red list Seychelles).
D i s t r i b u t i o n: Seychelles: Inner Seychelles (Silhouette).
Endemic.
description: Published as part of Madl, Michael, H, Inostemma, F, Leptacis & L, Platygaster, 2016, A catalogue of the family Platygastridae (Platygastroidea) of the Malagasy subregion. Part I: Subfamilies Platygastrinae and Sceliotrachelinae (Insecta: Hymenoptera), pp. 55-69 in Linzer biologische Beiträge 48 (1) on page 65, DOI: 10.5281/zenodo.5417040
title: Identification of virulence determinants in Burkholderia pseudomallei using a genomic island deletion approach
Creators: name: Logue, Carie-Anne
Publisher: name: Griffith University
Year: 2008
Subjects: subject: Burkholderia pseudomallei
subject: genomic island deletion approach
subject: genemic island deletion
subject: virulence determinanace
subject: bacillus
subject: Gram-negative bacillus
subject: B. pseudomallei
subject: malioidosis. Burkholderia species

description: Burkholderia pseudomallei is a Gram-negative bacillus inhabiting the soil and water of tropical and sub-tropical regions. Infection by B. pseudomallei causes a broad spectrum of diseases in humans and animals, collectively termed melioidosis. Infection occurs through inhalation, ingestion or percutaneous acquisition of bacteria. Melioidosis is associated with a high mortality rate and a high rate of relapse and can affect almost every host organ. Melioidosis has been suggested to be an emerging disease worldwide and the molecular basis of disease is poorly understood. The ability to sequence whole genomes has advanced research significantly. Comparisons between pathogenic and non-pathogenic organisms can be achieved more readily and can provide insights into possible virulence mechanisms. Analysis of the genomes of three Burkholderia species, B. pseudomallei, B. mallei and B. thailandensis, has revealed many differences and similarities. The differences contribute to the divergence between the three species and may suggest which genes are involved in virulence in the pathogenic species and those required for survival in the environment in avirulent species. Possibly, B. pseudomallei virulence is both multi-factorial and combinatorial and does not involve just a few virulence-associated genes...
Globalization and Capital Market Development in Nigeria
Creators: name: Akinwale, Samson Olusegun
name: Oludayo Elijah Adekunle
Publisher: name: figshare
Year: 2019
Subjects: subject: 130203 Economics, Business and Management Curriculum and Pedagogy
subject: FOS: Educational sciences

description: The Nigerian capital market has undergone different phases coupled with diverse challenges which impeded the growth of the market and its integration into the world financial market. This study investigated the effect of globalization on the capital market in Nigeria from 1986 to 2017 using secondary data from the Central Bank of Nigeria Statistical Bulletin. Augmented Dickey – Fuller (ADF), Bound Test and Autoregressive Distributed Lag were employed to evaluate the effect of trade openness, foreign direct investment, and foreign portfolio investment on market capitalization in Nigeria. The results of the unit root test revealed that both trade openness and market capitalization were stationary at first difference while foreign direct investment and foreign portfolio investment were stationary at level. Also, the long-run equilibrium relationship was found among the variables based. The ARDL revealed that both trade openness and foreign portfolio investment had a positive and significant effect on market capitalization both in short run and long run while foreign direct investment had a negative and insignificant effect on market capitalization in short run and long run. In line with findings, it was concluded that globalization had a significant effect on the economy through openness and the inflow of foreign capital. The study recommended that there is a need for total liberalization of the economy in order to reap the full benefits of globalization in the economy. The government should formulate a policy that will reduce or discourage the expatriation of profit by foreign investors to foreign countries. Finally, innovative financial instruments should be introduced in the market for the purpose of attracting foreign investors.
Sustainable tourism in protected areas? : an ecological economics case study of the Wet Tropics World Heritage Area
Creators: name: Driml, Sally M.
Publisher: name: The Australian National University
Year: 1996

description: This thesis is concerned broadly with operationising the concept of sustainable development. A particular natural resource use, tourism in protected areas, is selected for investigation in this context. A working definition for "sustainable tourism in protected" areas is developed, based on reviews of the literature on sustainable development and tourism in protected areas. The thesis takes an ecological economics approach to the question of operationalising the concept of sustainable tourism in protected areas. The reasons for selecting an ecological economics approach are discussed. An ecological economics model is developed in order to try to measure whether the criteria and conditions proposed for sustainable tourism in protected areas are being met. The model is then applied to a case study of the Wet Tropics World Heritage Area in North Queensland, Australia. This area of tropical rainforest houses numberous rare and endangered species. It also has experienced rapid growth in tourism in recent years, and tourist numbers are expected to double between the years 1992 and 2001. The budget for management has recently been reduced significantly. The case study shows that the criteria and conditions for sustainable tourism in the Wet tropics World Heritage Area are currently not being met. This is mainly because the budget dedicated to management is less than that considered adequate to avoid exceeding limits of acceptable ecological change. The net economic benefits, conditional upon adequate funding being provided for management, are positive and large. the effects of introducing an entry fee to raise funds for management are modelled. Conclusions are drawn on the application of the model to the Wet Tropics World Heritage Area and the broader application of the approach developed.