cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On the Accretion-Fed Growth of Neutron Stars During Common Envelope
Creators: name: MacLeod, Morgan
name: Ramirez-Ruiz, Enrico
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: This paper models the orbital inspiral of a neutron star (NS) through the envelope of its giant-branch companion during a common envelope (CE) episode. These CE episodes are necessary to produce close pairs of NSs that can inspiral and merge due to gravitational wave losses in less than a Hubble time. Because cooling by neutrinos can be very efficient, NSs have been predicted to accumulate significant mass during CE events, perhaps enough to lead them to collapse to black holes. We revisit this conclusion with the additional consideration of CE structure, particularly density gradients across the embedded NS's accretion radius. This work is informed by our recent numerical simulations that find that the presence of a density gradient strongly limits accretion by imposing a net angular momentum to the flow around the NS. Our calculations suggest that NSs should survive CE encounters. They accrete only modest amounts of envelope material, $\lesssim 0.1M_\odot$, which is broadly consistent with mass determinations of double NS binaries. With less mass gain, NSs must spiral deeper to eject their CE, leading to a potential increase in mergers. The survival of NSs in CE events has implications for the formation mechanism of observed double NS binaries, as well as for predicted rates of NS binary gravitational wave inspirals and their electromagnetic counterparts.
description: 5 pages, 4 figures. This version fixes an error in the published Fig 3 x-axis label which reads "log a [au]" rather than "a [au]"
Neutrino masses from SUSY breaking in radiative seesaw models
Creators: name: Figueiredo, A. J. R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Radiatively generated neutrino masses ($m_ν$) are proportional to supersymmetry (SUSY) breaking, as a result of the SUSY non-renormalisation theorem. In this work, we investigate the space of SUSY radiative seesaw models with regard to their dependence on SUSY breaking ($\require{cancel}\cancel{\text{SUSY}}$). In addition to contributions from sources of $\cancel{\text{SUSY}}$ that are involved in electroweak symmetry breaking ($\cancel{\text{SUSY}}_\text{EWSB}$ contributions), and which are manifest from $\langle F^\dagger_H \rangle = μ\langle \bar H \rangle \neq 0$ and $\langle D \rangle = g \sum_H \langle H^\dagger \otimes_H H \rangle \neq 0$, radiatively generated $m_ν$ can also receive contributions from $\cancel{\text{SUSY}}$ sources that are unrelated to EWSB ($\cancel{\text{SUSY}}_\text{EWS}$ contributions). We point out that recent literature overlooks pure-$\cancel{\text{SUSY}}_\text{EWSB}$ contributions ($\propto μ/ M$) that can arise at the same order of perturbation theory as the leading order contribution from $\cancel{\text{SUSY}}_\text{EWS}$. We show that there exist realistic radiative seesaw models in which the leading order contribution to $m_ν$ is proportional to $\cancel{\text{SUSY}}_\text{EWS}$. To our knowledge no model with such a feature exists in the literature. We give a complete description of the simplest model-topologies and their leading dependence on $\cancel{\text{SUSY}}$. We show that in one-loop realisations $L L H H$ operators are suppressed by at least $μ\, m_\text{soft} / M^3$ or $m_\text{soft}^2 / M^3$. We construct a model example based on a one-loop type-II seesaw. An interesting aspect of these models lies in the fact that the scale of soft-$\cancel{\text{SUSY}}$ effects generating the leading order $m_ν$ can be quite small without conflicting with lower limits on the mass of new particles.
description: Accepted for publication in European Physical Journal C; 23 pages + appendices; references updated; minor revisions; extended conclusions
Antipsychotic-induced vacuous chewing movements and extrapyramidal side effects are highly heritable in mice
Creators: name: Bogue, M A
name: Pratt, A L
name: Moy, S S
name: Quackenbush, C R
name: Adkins, D E
name: Wilhelmsen, K C
name: Sullivan, P F
name: van den Oord, E J
name: McLeod, H L
name: Cooper, T B
name: Crowley, J J
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Pharmacogenomics is yet to fulfill its promise of manifestly altering clinical medicine. As one example, a predictive test for tardive dyskinesia (an adverse drug reaction consequent to antipsychotic exposure) could greatly improve the clinical treatment of schizophrenia but human studies are equivocal. A complementary approach is the mouse-then-human design in which a valid mouse model is used to identify susceptibility loci which are subsequently tested in human samples. We used inbred mouse strains from the Mouse Phenome Project to estimate the heritability of haloperidol-induced activity and orofacial phenotypes. 159 mice from 27 inbred strains were chronically treated with haloperidol (3 mg/kg/day via subdermal slow-release pellets) and monitored for the development of vacuous chewing movements (VCMs, the mouse analog of TD) and other movement phenotypes derived from open field activity and the inclined screen test. The test battery was assessed at 0, 30, 60, 90, and 120 days in relation to haloperidol exposure. As expected, haloperidol caused marked changes in VCMs, activity in the open field, and EPS. Unexpectedly, factor analysis demonstrated that these measures were imprecise assessments of a latent construct rather than discrete constructs. The heritability of a composite phenotype was ~0.9 after incorporation of the longitudinal nature of the design. Murine VCMs are a face valid animal model of antipsychotic-induced TD and heritability estimates from this study support the feasibility of mapping of susceptibility loci for VCMs.
A short note on the curvature perturbation at second order
Creators: name: Christopherson, Adam J.
name: Nalson, Ellie
name: Malik, Karim A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Working with perturbations about an FLRW spacetime, we compute the gauge-invariant curvature perturbation to second order solely in terms of scalar field fluctuations. Using the curvature perturbation on uniform density hypersurfaces as our starting point, we give our results in terms of field fluctuations in the flat gauge, incorporating both large and small scale behaviour. For ease of future numerical implementation we give our result in terms of the scalar field fluctuations and their time derivatives.
description: 10 pages; v2: 11 pgs, added appendix, typos corrected. version to appear in Class. Quantum Grav
title: The Role of Black Women in the American Civil Rights Movement
Creators: name: Levins, Ashley
Publisher: name: Old Dominion University Libraries
Year: 2023

description: This essay examines the role of Black women in the American Civil Rights Movement. This is achieved through a review of literature, followed by an analysis of the First Wave of Feminism, prominent Black female leaders, and the issue of erasure of Black women. Ultimately, the essay argues that Black women were the spine of the American Civil Rights Movement, despite their historical erasure.
A factor analysis of urban-to-rural migrants’ intention of transition to farming
Creators: name: Hong, Yunsil
name: Hong, Yunsil
Publisher: name: Unknown
Year: 2021
Subjects: subject: Community/Rural/Urban Development
subject: Labor and Human Capital
subject: urban-to-rural migrant
subject: urban-to-rural migrants survey
subject: intention of transition to farming

description: This paper identified various factors causing urban-to-rural migrants to have the intention of farming. The 2019 urban-to-rural migrants survey showed that 12.3% of the migrants with no experience of farming had the intention of farming. If this intention transforms into action, the transition will make up for a gradual decrease of urban-to-rural farming. This paper’s analysis was based on the microdata of the 2016 urban-to-rural migrants survey with 1006 samples—the only microdata of the year available. The specific factors were selected and made as variables in a model from the survey questionnaire considering the urban-to-rural migration-related, economic, sociocultural, and demographic aspects. Preparation duration, education, and governmental policy in the urban-to-rural migration-related aspect were statistically significant. Family income prospects, agriculture-related jobs, and business start-up experience in the economic aspect were statistically significant. Relationship with other residents and satisfaction levels in the sociocultural aspect and the number of family in the demographic information were statistically significant. All the statistically significant variables were positive except business start-up experience. Implications were added based on the results.
Genome-wide association study of antipsychotic-induced QTc interval prolongation
Creators: name: Jia, P
name: van den Oord, E J C G
name: Åberg, K
name: Bukszár, J
name: Adkins, D E
name: Zhao, Z
name: Stroup, T S
name: Sullivan, P F
name: Lieberman, J A
name: McClay, J L
name: Perkins, D
name: Liu, Y
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: QT prolongation is associated with increased risk of cardiac arrhythmias. Identifying the genetic variants that mediate antipsychotic induced prolongation may help to minimize this risk, which might prevent the removal of efficacious drugs from the market. We performed candidate gene analysis and five drug specific genome-wide association studies (GWAS) with 492K SNPs to search for genetic variation mediating antipsychotic induced QT prolongation in 738 schizophrenia patients from the Clinical Antipsychotic Trial of Intervention Effectiveness (CATIE) study.Our candidate gene study suggests the involvement of NOS1AP and NUBPL (p-values =1.45×10−05 and 2.66×10−13, respectively). Furthermore, our top GWAS hit achieving genome-wide significance, defined as a q-value <0.10, (p-value =1.54×10−7, q-value =0.07), located in SLC22A23, mediated the effects of quetiapine on prolongation. SLC22A23 belongs to a family of organic ion transporters that shuttle a variety of compounds including drugs, environmental toxins, and endogenous metabolites across the cell membrane. This gene is expressed in the heart and is integral in mouse heart development. The genes mediating antipsychotic induced QT prolongation partially overlap with the genes affecting normal QT interval variation. However, some genes may also be unique for drug induced prolongation. This study demonstrates the potential of GWAS to discover genes and pathways that mediate antipsychotic induced QT prolongation.
Note on the dark matter explanation of the ARCADE excess and AMS data
Creators: name: Fairbairn, Malcolm
name: Grothaus, Philipp
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In this paper we show that positron data from AMS seems to rule out the explanation of the ARCADE isotropic radio background excess in terms of self-annihilating dark matter. In earlier works it was found that leptonic annihilation channels of light dark matter provide a good fit to the excess due to synchrotron emission of the final state particles. However, limits on the self-annihilation cross-section derived from the positron data of AMS now severely constrain light self-annihilating dark matter and cross-sections below that of a thermal relic are already tested for leptonic annihilation channels. Combining these two results, we conclude that an explanation of the excess in the radio background in terms of self-annihilating dark matter is excluded.
description: 3 pages, 3 figures, references added, matches published version
THE DEVELOPMENT OF THE GLUTAMATERGIC NEURONS IS SHAPED BY IL-1BETA
Creators: name: MARCHETTI, NATALIA
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: The developing brain is exquisitely sensitive to immune system activation that, shaping the organism?s response to infections, may impact the development of the nervous system increasing susceptibility to behavioural and neurological diseases later in life. Experimental studies, in particular, link dysregulated production of pro-inflammatory cytokines (i.e. IL6 and IL-1?) to the onset of neurodevelopmental diseases later in life. Neonatal immune activation, through cytokines production, can have direct long-term effects on neuronal function by interfering with neurotransmitter function, altering the expression of synaptic proteins, producing differential neuronal activation. We addressed this specific topic in vitro by means of primary hippocampal neurons shortly exposed to a pulse of IL-1beta (0,05 ng/ml for 30 min) at different developmental stages, 3,7, and 14 days in vitro (DIV). Maturation of the glutamatergic system and any possible interference by IL-1beta has been evaluated in terms of expression of NMDAR subunits (GluN2A and GluN2B) and AMPAR subunits (GluA1 and GluA2), distribution at the post-synaptic site and ability to control intracellular Ca2+ homeostasis at full maturation (DIV 21). The exposure of hippocampal neurons to IL-1? at DIV 7 leads to a reduced GluN2A expression at DIV 21 that result in an increased GluN2B/GluN2A ratio, favouring the GluN2B-containing NMDARs. This effect is coupled to a reduced mRNA GluN2A transcription and is prevented blocking the Src family of tyrosine kinases suggesting the involvement of a GluN2B over-activation induced by IL-1?. These alterations, confirm at the post-synapses, are not evident when neurons are exposed to the cytokine at DIV 3 and 14, suggesting that IL-1? influences neuronal development only in a specific vulnerable period of growth. The effect is specifically operated by IL-1?, since no effects were assessed using another pro-inflammatory cytokine, TNF-?. The different NMDAR composition and distribution observed after IL-1? treatment at DIV 7 is coupled with an altered calcium homeostasis regulation under the control of NMDAR, with a reinforced GluN2B subunit contribution coupled with a weaker GluN2A subunit contribution. Increased expression of GluN2A over a prevalence of NMDAR sharing a GluN2B subunit is believe to be a crucial factor to prompt synaptic spine maturation from stubby to mushrooms spines. Accordingly to the delayed GluN2B/GluN2A shift, IL-1beta treatment at DIV 7 favours an higher amount of stubby and a lower amount of mushroom-shaped spines compared to controls. Our findings suggest the hypothesis that a transient increase of IL-1? during the early postnatal neuronal development leads to ?long-term? functional and structural alteration of the glutamatergic system development providing a molecular link between neuroinflammation and ?long-term? alteration of neuronal activity that could potentially predispose to neurodevelopmental disorders later in life.
title: Das barocke Festspiel als modernes Gesamtkunstwerk
Creators: name: Wilfing-Albrecht, Meike
Year: 2022

description: Egon Wellesz (1885–1974) erwarb sich in seiner langen Karriere als Musikwissenschaftler (in Wien und Oxford) wie auch als Komponist im erweiterten Kreis der Wiener Schule eine gleichermaßen hohe Reputation. Im Zuge seiner akademischen Tätigkeit trug er u. a. maßgeblich dazu bei, die Anfänge der sogenannten Barockmusik und insbesondere der barocken Festoper zu erforschen und entwickelte – basierend auf diesen Erkenntnissen – eine Opernreform für das zeitgenössische Musiktheater, die er innerhalb seiner wissenschaftlichen Schriften veröffentlichte. Hierbei verfolgte er das Ideal des Gesamtkunstwerkes, welches er wiederum in seinen in der ersten Hälfte des 20. Jahrhunderts entstandenen Bühnenwerken (hierunter vor allem die Alkestis und Die Bakchantinnen) praktisch umzusetzen versuchte. Im Rahmen der Dissertation wird zunächst Wellesz’ Verständnis von Barockmusik und speziell der Wiener Festoper definiert sowie die Einflüsse von u. a. Guido Adler, Arnold Schönberg und Gustav Mahler nachvollzogen. Hiernach folgt eine historische Kontextualisierung, bei der ein Blick auf die angebliche Krise der Oper in der ersten Hälfte des 20. Jahrhunderts geworfen wird, die Wellesz als Auslöser für seine Reform diente. Auf Grundlage einer umfassenden Darstellung von Welleszʼ Opernreform sowie seiner Vorstellung eines zeitgenössischen Gesamtkunstwerkes werden dessen Bühnenwerke in Hinblick auf eine Beeinflussung durch seine historischen Studien untersucht. Hierbei geht es primär um die Elemente, die auf historischen Vorbildern beruhen, jedoch gleichzeitig mit modernen Mitteln dargestellt werden, d. h. das Libretto, die Bühne (mit Bühnenbild, Lichtregie, Kostümen usw.) sowie der Tanz.
title: The role of geography in the development of Paquimé: a cost-surface analysis to determine patterns of trade for copper bells from western Mexico into the southwestern United States
Creators: name: Hale, Lynn
Publisher: name: Georgia State University
Year: 2004

description: Paquimé is a pre-Hispanic site in the northern Mexican state of Chihuahua. The chronology for its development begins with an understanding of the events of the Medio period, AD 800-1520. This period is divided into Phase I (AD 800-1250) and concludes in Phase II (AD 1250-1520). During Phase I, Paquimé is little more than a village in the middle of the Chihuahuan desert. In the span of a few years near the beginning of Phase II, Paquimé exploded onto the international scene, exhibiting characteristics of both Mesoamerica and the American Southwest.

Archaeologically, Paquimé is a site rich in architecture, public works, and artifact assemblages. Unfortunately, archaeologists disagree about the activities that caused these features to be at Paquimé. Despite years of work there, it is still unclear to archaeologists why Paquimé developed more than other communities in the region. Paquimé may have participated in the trade network between what is today Mesoamerica and the American Southwest because of its convenient geographical location The precise role of Paquimé in the long-distance trade routes is not known, and the level of its importance is in dispute.

Why did Paquimé grow into one of the largest pueblos of the Southwest? Exchange of exotica between what is now the United States and Mexico may have been a factor in the growth of Paquimé. The movement of goods through exchange networks provided residents of polities like Paquimé with access to foreign-produced 'elite' goods. The movement of 2 these goods through space likely occurred along the path or paths of least resistance - the trade route(s) that offered optimum movement with minimum effort. It also provided opportunities for Paquimé to grow and develop through interactions with other polities.

This research project has been designed to utilize a Geographic Information Systems (GIS) to elucidate the impetus for the development of Paquimé, a pre-Hispanic polity that developed in the northern Mexican state of Chihuahua during Phase II of the Medio period.

(Abstract is an excerpt of the thesis introduction).
Density Classification Quality of the Traffic-majority Rules
Creators: name: Redeker, Markus
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cellular Automata and Lattice Gases (nlin.CG)
subject: FOS: Physical sciences
subject: B.6.1
subject: 37B15 (Primary), 60J10, 60J70 (Secondary)

description: The density classification task is a famous problem in the theory of cellular automata. It is unsolvable for deterministic automata, but recently solutions for stochastic cellular automata have been found. One of them is a set of stochastic transition rules depending on a parameter $η$, the traffic-majority rules. Here I derive a simplified model for these cellular automata. It is valid for a subset of the initial configurations and uses random walks and generating functions. I compare its prediction with computer simulations and show that it expresses recognition quality and time correctly for a large range of $η$ values.
description: 40 pages, 9 figures. Accepted by the Journal of Cellular Automata. (Some typos corrected; the numbers for theorems, lemmas and definitions have changed with respect to version 1.)
IMPLEMENTAZIONE DI MODELLI PER VARIABILI RISPOSTA QUALITATIVE E MISURE PER LA VALUTAZIONE DELLA CAPACIT� PREDITTIVA: APPLICAZIONE ALLA STADIAZIONE DELLA FIBROSI EPATICA IN PAZIENTI CON EPATITE CRONICA C.
Creators: name: LANZONI, MONICA
Publisher: name: Universit� degli Studi di Milano
Year: 2014

description: In the context of medical, epidemiological and health organization research there are many situations in which it is necessary to develop prediction models that identify multiclass categorical variable outcomes, where the latter may be nominal or ordered. When the outcome variable is binary, consolidated modeling techniques based on logistic function are available. On the contrary, up to now, models for multiple classes outcome, taking into account ordinality or not, were developed from a theoretical point of view but not widespreadly used. Limited software availability and the difficulty in making the results suitable for pratictioners in a simple way are the main reasons for such a limited use. This has leaded to many published studies in wich a dichotomization of the outcome variable was introduced in order to allow the application of the logistic model, thus losing part of the data information and reducing the power of results. This dissertation provides an overview of the available theoretical models and shows their implementation for a problem of three-classes diagnostic classification of the severity of liver fibrosis in HCV patients. Moreover, a representation of the selected model by means of immediately readable nomograms is also provided.
Higher-derivative mechanics with N=2 l-conformal Galilei supersymmetry
Creators: name: Masterov, Ivan
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The analysis previously developed in [J. Math. Phys. 55 (2014) 102901] is used to construct systems which hold invariant under N=2 l-conformal Galilei superalgebra. The models describe two different supersymmetric extensions of a free higher-derivative particle. Their Newton-Hooke counterparts are derived by applying appropriate coordinate transformations.
description: 14 pages, published version with minor changes
NATURA E CULTURA: ALLE ORIGINI DI UNA DICOTOMIA
Creators: name: LONGO, TOMMASO
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: ABSTRACT Nature (?????) and (?????) are two key terms of a long-standing debate in ancient Greek philosophy. My dissertation is chiefly concerned with the ways the concept of ?culture? (?????) is related with that of ?nature? (?????) in the history of ancient ethical and political thought. In particular, it aims to reconstruct and assess the historical-philosophical path leading to the formulation of the dichotomy between ????? and ????? in the Sophistic debate. On purpose, my dissertation is divided, as to the structure, into three main parts: 1. the first chapter is entirely dedicated to the ways nature and culture are conceptualised in some medical treatises of the Hippocratic Collection (e.g. Airs, waters and places and The sacred disease). I will show up that the two concepts are deeply interconnected and interwoven here in such a way that we are not allowed to trace clear-cut boundaries among them. 2. the second chapter is focused on Archelaus. I will attempt to argue that nature and culture are conceived for the first time as two autonomous and independent concepts from one another in his doctrine. On one hand, Archelaus promotes a conception of nature in merely materialistic terms, ruling out thereby the possibility that nature is endowed with some intrinsic ethical qualities. On the other one, he is furthermore reported by ancient sources as claiming that the origins of ethics (DK 60 A1) and of politics (DK 60 A4) are grounded on a conventional basis and, therefore, do not exist at a natural level. According to the interpretation I will be endorsing, human beings give rise to socio-political institutions and conventions for they cannot appeal to any kind of natural ethics. Therefore, political conventionalism and ethical subjectivism can be considered as pragmatic ways of reacting to the endorsement of a radical form of materialism. 3. lastly, the third chapter is about two Sophists, namely Protagoras and Antiphon. As we shall see, Protagoras aims to overcome the dichotomy between nature and culture, pointing to the evidence that human beings are by nature social and political animals. On the opposite corner, Antiphon will oppose nature to culture and remark that the laws of a city are often in contrast with the natural necessities, needs and desires of human beings. To conclude, I hope to have unravelled and displayed some of the major theoretical problems involved in relationship between nature and culture and the ways the process by which they come to be opposed one to another.
Nucleotide excision repair gene variants and association with survival in osteosarcoma patients treated with neoadjuvant chemotherapy
Creators: name: Talamini, R
name: Toffoli, G
name: Hattinger, C M
name: Scotlandi, K
name: Zanusso, C
name: Serra, M
name: Alberghini, M
name: Biason, P
name: Innocenti, F
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The aim of this study was to investigate the role of common polymorphisms in the NER pathway genes in the tumorigenesis of osteosarcoma and in the response to DNA damaging therapies, such as cisplatin-based neoadjuvant therapy. XPD (rs13181 and rs1799793), XPG (rs17655), and ERCC1 (rs3212986 and rs11615) polymorphisms were analysed in a group of 130 homogenously-treated patients with high-grade osteosarcoma for association with event free survival (EFS) using Kaplan-Meier plots and log-rank test. A positive association was observed between both XPD SNPs and an increased EFS (HR= 0.34, 95% CI 0.12-0.98 and HR= 0.19, 95% CI 0.05-0.77, respectively). We had also performed a case-control study for relative risk to develop osteosarcoma. Patients carrying at least one variant allele of XPD rs1799793 had a reduced risk of developing osteosarcoma compared to wild type patients (OR=0.55, 95% CI 0.36-0.84).This study suggests that XPD rs1799793 could be a marker of osteosarcoma associated with features conferring either a better prognosis or a better outcome after platinum therapy, or both.
title: Philosophieren mit Literatur
Creators: name: Petritsch, Marlies
Year: 2022

description: In der deutschsprachigen Forschung zu den beiden Gebieten der Philosophie und Literatur liegen vor allem berühmte Philosoph:innen und Autor:innen der deutschen Geschichte im Fokus. Über den zeitgenössischen norwegischen Autor Jostein Gaarder und seine Romane lässt sich bis dato keine wissenschaftliche Untersuchung in deutscher Sprache finden. Diese Masterarbeit möchte an dieser Stelle ansetzen und versuchen, diese Forschungslücke zu füllen. Dabei wird die Forschungsfrage beantwortet, inwiefern die Jugendromane Jostein Gaarders, Das Kartengeheimnis und Sofies Welt, erfolgreich sind, direkt und indirekt Philosophie gehaltvoll zu betreiben, und welche Mittel und Methoden der Autor dafür verwendet. Philosophie und Literatur werden zuerst allgemein auf Parallelen und Gemeinsamkeiten in Wirken und Funktionen geprüft. Anschließend werden verschiedene Theorien und Konzepte der Hermeneutik vorgestellt, die der darauffolgenden Analyse der Romane dienen. Die beiden Jugendbücher Gaarders werden daraufhin in ihren fiktionalen sowie philosophischen Inhalten vorgestellt. Dabei zeigt sich, dass Gaarder Philosophie durch literarische Mittel wie Metaphern und anhand von Beispielen sowie Charakteren und Handlungssträngen vielschichtig an seine Leser:innen vermittelt. Die jugendlichen Hauptcharaktere und deren Leser:innen erleben dadurch Philosophie als relevant und allumfassend. Sie erkennen schließlich Philosophie als treibende, rettende und erstrebenswerte Kraft des Lebens.
QCD sum rule Study of the $d^*(2380)$
Creators: name: Chen, Hua-Xing
name: Cui, Er-Liang
name: Chen, Wei
name: Steele, T. G.
name: Zhu, Shi-Lin
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We systematically construct $I(J^P)=0(3^+)$ six-quark local interpolating currents without derivative operators. We discuss the best choice of operator, and select three $Δ$-$Δ$ like operators to perform QCD sum rule analyses to calculate the mass of the $d^*(2380)$. The mass extracted from this analysis is $M_{d^*} = 2.4\pm0.2$ GeV, consistent with the $d^*(2380)$ mass observed by the WASA detector at COSY. We also obtain a sum-rule lower mass bound $M_{d^*} > 2.25$ GeV. We also consider the effect of mixing of singlet dibaryon fields with the same quantum numbers, and perform the QCD sum rule analysis of the mixed interpolating current and extract the mass of the $d^*(2380)$ and its lower mass bound. With optimized mixing parameters, we find that the mixed current does not change the numerical result significantly.
description: 9 pages, 4 figures
Survey of US public attitudes toward pharmacogenetic testing
Creators: name: Lipkus, I R
name: O'Daniel, J M
name: Agans, R
name: Tindall, G M
name: Haga, S B
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: To assess public attitudes and interest in pharmacogenetic (PGx) testing, we conducted a random-digit-dial telephone survey of U.S. adults, achieving a response rate of 42% (n=1139). Most respondents expressed interest in PGx testing to predict mild or serious side effects (73% ±3.29% and 85% ±2.91%, respectively), guide dosing (91%) and assist with drug selection (92%). Younger individuals (ages 18–34) were more likely to be interested in PGx testing to predict serious side effects (vs. ages 55+), as well as Whites, those with a college degree, and who had experienced side effects from medications. However, most respondents (78% ±3.14%) were not likely to have a PGx test if there was a risk that their DNA sample or test result could be shared without their permission. Given differences in interest among some groups, providers should clearly discuss the purpose of testing, alternative testing options (if available), and policies to protect patient privacy and confidentiality.
Survey Findings:: Social Justice Dialogues in STEM Education Fall 2022 LC
Creators: name: Taylor, Robin
Publisher: name: QUBES Educational Resources
Year: 2023

description: Survey findings for the learning community (LC), Social Justice Dialogues in STEM Ed, facilitated by Drs. Desiree Forsythe (Chapman University) and Megan Jones (University of Rhode Island) – with support from Dr. Kaitlin Bonner (St. John Fisher College). The LC included five synchronous sessions from October 12th through December 7th, aimed to explore difficult dialogues of social inequities in STEM classrooms using short readings, discussions, and mini-workshops.
Phenomenological Modeling of Memristive Devices
Creators: name: Merrikh-Bayat, Farnood
name: Hoskins, Brian
name: Strukov, Dmitri B.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present a computationally inexpensive yet accurate phenomenological model of memristive behavior in titanium dioxide devices by fitting experimental data. By design, the model predicts most accurately I-V relation at small non-disturbing electrical stresses, which is often the most critical range of operation for circuit modeling. While the choice of fitting functions is motivated by the switching and conduction mechanisms of particular titanium dioxide devices, the proposed modeling methodology is general enough to be applied to different types of memory devices which feature smooth non-abrupt resistance switching.
description: 17 pages, 5 figures
Survey Findings: Exploring Open Education LC
Creators: name: Taylor, Robin
Publisher: name: QUBES Educational Resources
Year: 2023

description: Survey findings for the learning community (LC), Exploring Open Education Practices and Pedagogy (Spring 2022), facilitated by Drs. Carlos Goller (North Carolina State University) and Melanie Lenahan (Raritan Valley Community College) – with support from Dr. Kaitlin Bonner (St. John Fisher College). The LC included five synchronous sessions from March 14 through April 18, aimed to explore basic tools for open education practices using short readings, discussions, and mini-workshops.
Rural residents' decision and compensation amount for providing community care for the elderly
Creators: name: Kim, Nam-Hoon
name: Kim, Nam-Hoon
Publisher: name: Unknown
Year: 2021
Subjects: subject: Community/Rural/Urban Development
subject: community care
subject: interval regression
subject: ordered logistic regression

description: Community care led by rural residents is emerging as an alternative to overcome the flawed care system for the elderly in rural areas. However, no paper has studied whether rural residents would participate in providing care for the rural elderly. In this study, we investigate whether rural residents are willing to provide community care to the elderly who need care and evaluate the amount of the willingness to accept it. For this purpose, we conducted empirical analyses by using (ordered) logistic and interval regressions with the survey of 586 farmers living in rural areas. The result shows that 60% of respondents were willing to provide care to the elderly and the amount of the willingness to accept (WTA) for providing care was around 5,000 won. It also shows that residents who had economic difficulties or needed non-agricultural income tended to participate in care. Female and younger residents also expressed a higher amount of WTA because they could work with higher wages in other jobs. For the policy implication, we suggest that the government cooperate with rural communities to support sufficient compensation for part-time care services so that more rural residents can participate in community care.
The effect of non-Gaussianity on error predictions for the Epoch of Reionization (EoR) 21-cm power spectrum
Creators: name: Mondal, Rajesh
name: Bharadwaj, Somnath
name: Majumdar, Suman
name: Bera, Apurba
name: Acharyya, Ayan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The Epoch of Reionization (EoR) 21-cm signal is expected to become increasingly non-Gaussian as reionization proceeds. We have used semi-numerical simulations to study how this affects the error predictions for the EoR 21-cm power spectrum. We expect $SNR=\sqrt{N_k}$ for a Gaussian random field where $N_k$ is the number of Fourier modes in each $k$ bin. We find that non-Gaussianity is important at high $SNR$ where it imposes an upper limit $[SNR]_l$. For a fixed volume $V$, it is not possible to achieve $SNR > [SNR]_l$ even if $N_k$ is increased. The value of $[SNR]_l$ falls as reionization proceeds, dropping from $\sim 500$ at $\bar{x}_{HI} = 0.8-0.9$ to $\sim 10$ at $\bar{x}_{HI} = 0.15 $ for a $[150.08\, {\rm Mpc}]^3$ simulation. We show that it is possible to interpret $[SNR]_l$ in terms of the trispectrum, and we expect $[SNR]_l \propto \sqrt{V}$ if the volume is increased. For $SNR \ll [SNR]_l$ we find $SNR = \sqrt{N_k}/A $ with $A \sim 0.95 - 1.75$, roughly consistent with the Gaussian prediction. We present a fitting formula for the $SNR$ as a function of $N_k$, with two parameters $A$ and $[SNR]_l$ that have to be determined using simulations. Our results are relevant for predicting the sensitivity of different instruments to measure the EoR 21-cm power spectrum, which till date have been largely based on the Gaussian assumption.
description: Accepted for publication in MNRAS Letters. The definitive version is available at http://mnrasl.oxfordjournals.org/content/449/1/L41
Survey Findings:: Social Justice Dialogues in STEM Education LC
Creators: name: Taylor, Robin
Publisher: name: QUBES Educational Resources
Year: 2023

description: Survey findings for the learning community (LC), Social Justice Dialogues in STEM Ed, facilitated by Drs. Bryan Dewsbury (Florida Institute of Technology) and Desiree Forsythe (Rochester Institute of Technology) – with support from Dr. Kaitlin Bonner (St. John Fisher College). The LC included five synchronous sessions from April 6th through May 31st, aimed to explore difficult dialogues of social inequities in STEM classrooms using short readings, discussions, and mini-workshops.
Survey Findings: Exploring Open Education Fall 2022 LC
Creators: name: Taylor, Robin
Publisher: name: QUBES Educational Resources
Year: 2023

description: Survey findings for the learning community (LC), Exploring Open Education Practices and Pedagogy (Spring 2022), facilitated by Drs. Carlos Goller (North Carolina State University) and Melanie Lenahan (Raritan Valley Community College) – with support from Dr. Kaitlin Bonner (St. John Fisher College). The LC included five synchronous sessions from October 05 through November 09, aimed to explore basic tools for open education practices using short readings, discussions, and mini-workshops.
title: Behaviorismus und Serious Games: eine untrennbare Konbination?
Creators: name: Kaiser, Sandra
Year: 2022

description: Diese Masterarbeit fragt nach Möglichkeiten, wie die drei Lerntheorien Behaviorismus, Kognitivismus und Konstruktivismus in ein Serious Game inkludiert, das Serious Games "Ein Tag Deutsch in der Pflege" dahingehend modelliert und wie eine Entwicklung der drei Identitäten nach Michael Wagner gefördert werden kann. Dafür finden leitfadengestützte Interviews beziehungsweise leitfadengestützte Expert*inneninterviews mit einer Expertin, einer Entwicklerin, drei Lernenden und einer Lehrperson statt. Zuvor gesandte Kriterienlisten sind von den Interviewteilnehmer*innen auszufüllen. Die Interviews werden mit Hilfe der Software MAXQDA transkribiert und kategorisiert. Dafür wird die qualitative zusammenfassende Inhaltsanalyse nach Mayring mit einer induktiven und deduktiven Kategorienbildung herangezogen. Manche lerntheoretischen Merkmale sind einfach, andere schwierig und wieder andere unmöglich umzusetzen. Die Einschätzung, ab wann von einem zutreffenden Kriterium zu sprechen ist, hängt von der jeweiligen Interpretation ab. Die allgemeinen Vorschläge zur Umsetzung helfen bei den Ideen zur Modellierung des Lernspiels "Ein Tag Deutsch in der Pflege". Für die Entwicklung der drei Identitäten gibt es verschiedene interne und externe Faktoren, die je nach Interviewpartner*in einen anderen Stellenwert einnehmen. Alle drei Teile der Forschungsfrage sind jedoch mit unterschiedlichen Herausforderungen verbunden, die es zu bedenken gilt. Dennoch bietet diese Masterarbeit verschiedene Möglichkeiten zur Umsetzung an.
A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen
Creators: name: Innocenti, F
name: De Mattia, E
name: Zanusso, C
name: Pella, N
name: Lonardi, S
name: Polesel, J
name: Errante, D
name: Cecchin, E
name: D'Andrea, M
name: Toffoli, G
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The discovery of pharmacogenomic markers in colorectal cancer (CRC) could be setting-specific. FOLFOX4 is employed in the adjuvant and metastatic setting in CRC. This prospective study is aimed to validate in the adjuvant setting the pharmacogenomic markers of toxicity reported in the metastatic setting (that is, GSTP1-rs947894, and -rs1138272; GSTM1-null genotype; AGXT-rs4426527, -rs34116584 and del-74 bp), and to discover additional markers. CRC patients (n = 144) treated with adjuvant FOLFOX4 were genotyped for 57 polymorphisms in 29 genes. Grade ≥2 neurotoxicity was associated false discovery rate-adjusted q-value <0.1) with single-nucleotide polymorphisms in ABCC1 (rs2074087: odds ratio = 0.43(0.22–0.86)), and ABCC2 (rs3740066: 2.99(1.16–7.70); rs1885301: 3.06(1.35–6.92); rs4148396: 4.69(1.60–13.74); rs717620: 14.39(1.63–127.02)). hMSH6-rs3136228 was associated with grade 3–4 neutropenia (3.23(1.38–7.57), q-value = 0.0937). XRCC3-rs1799794 was associated with grade 3–4 non-hematological toxicity (8.90(2.48–31.97), q-value = 0.0150). The markers previously identified in metastatic CRC were not validated. We have identified new markers of toxicity in genes of transport and DNA repair. If validated in other studies, they could help to identify patients at risk of toxicity.
Relative entropy in higher spin holography
Creators: name: Datta, Shouvik
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We examine relative entropy in the context of the higher-spin/CFT duality. We consider 3$d$ bulk configurations in higher spin gravity which are dual to the vacuum and a high temperature state of a CFT with $\mathcal{W}$-algebra symmetries in presence of a chemical potential for a higher spin current. The relative entropy between these states is then evaluated using the Wilson line functional for holographic entanglement entropy. In the limit of small entangling intervals, the relative entropy should vanish for a generic quantum system. We confirm this behaviour by showing that the difference in the expectation values of the modular Hamiltonian between the states matches with the difference in the entanglement entropy in the short-distance regime. Additionally, we compute the relative entropy of states corresponding to smooth solutions in the $SL(2,\mathbb{Z})$ family with respect to the vacuum.
description: 29 pages. Published version. All relative entropies are calculated with respect to the vacuum
ESSAYS ON CLIMATE CHANGE ECONOMICS AND POPULATION DYNAMICS
Creators: name: LUPI, VERONICA
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: This thesis analyses the relationship between population dynamics and the environment. In particular, there are two reasons to be concerned with population when dealing with climate change. On the one hand, population's size is one of the main driver of emissions. On the other hand, climate change might affect fertility and mortality rates, as heat waves and jumps in temperature can modify the ability of people to procreate, may induce unexpected death of infants at birth and can worsen the conditions of people already sick. Chapter one gives an overview about the current debate on these themes and the previous literature. In the second Chapter we analyze the mutual relation between population growth and climate change: on the one hand, population is a driver of carbon emissions which is an important determinant of climate change; on the other hand, climate change affects the mortality rate which determines the net rate of population growth. Such population-climate feedback suggests that demographic policy may be an alternative instrument to reduce the social costs associated with climate change. We explore this possibility by introducing endogenous fertility choices and temperature-related mortality in a global integrated assessment model of climate-economy, and we consider a population policy aimed at imposing a ceiling on population growth. We show that accounting for endogenous population change substantially increases the social costs of environmental policies, but relying on demographic policy reduces such costs by 16\% by $2050$. This clearly shows that population change does matter and demographic policy may be a valid tool to promote sustainable development.
Number Counts and Dynamical Vacuum Cosmologies
Creators: name: Devi, N. Chandrachani
name: Borges, H. A.
name: Carneiro, S.
name: Alcaniz, J. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study non-linear structure formation in an interacting model of the dark sector of the Universe in which the dark energy density decays linearly with the Hubble parameter, $ρ_Λ \propto H$, leading to a constant-rate creation of cold dark matter. We derive all relevant expressions to calculate the mass function and the cluster number density using the Sheth-Torman formalism and show that the effect of the interaction process is to increase the number of bound structures of large masses ($M \gtrsim 10^{14} M_{\odot}h^{-1}$) when compared to the standard $Λ$CDM model. Since these models are not reducible to each other, this number counts signature can in principle be tested in future surveys.
description: 6 pages, 3 figures. Accepted for publication in MNRAS
Topological properties of linear circuit lattices
Creators: name: Albert, Victor V.
name: Glazman, Leonid I.
name: Jiang, Liang
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Motivated by the topologically insulating (TI) circuit of capacitors and inductors proposed and tested in arXiv:1309.0878, we present a related circuit with less elements per site. The normal mode frequency matrix of our circuit is unitarily equivalent to the hopping matrix of a quantum spin Hall insulator (QSHI) and we identify perturbations that do not backscatter the circuit's edge modes. The idea behind these models is generalized, providing a platform to simulate tunable and locally accessible lattices with arbitrary complex spin-dependent hopping of any range. A simulation of a non-Abelian Aharonov-Bohm effect using such linear circuit designs is discussed.
description: 5 pages, 2 figures, 1 table + supplement (2 pages); Editor's Suggestion (in press); featured in Condmat journal club at http://www.condmatjournalclub.org/?p=2528