cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Maternal Mediterranean diet in pregnancy and newborn DNA methylation: a meta-analysis in the PACE Consortium
Creators: name: Rifas-Shiman, S.L
name: Mulder, R.H
name: Felix, J.F
name: de Vries, J.H.M
name: Starling, A.P
name: Oken, E
name: Johnson, L
name: Sharp, G.C
name: Bustamante, M
name: Fore, R
name: Jaddoe, V.W.V
name: Mancano, G
name: Dabelea, D
name: Nounu, A
name: Friedman, C
name: Vrijheid, M
name: Hivert, M.-F
name: Küpers, L.K
name: Fernández-Barrés, S
Publisher: name: Taylor and Francis Ltd.
Year: 2022

description: Higher adherence to the Mediterranean diet during pregnancy is related to a lower risk of preterm birth and to better offspring cardiometabolic health. DNA methylation may be an underlying biological mechanism. We evaluated whether maternal adherence to the Mediterranean diet was associated with offspring cord blood DNA methylation. We meta-analysed epigenome-wide association studies (EWAS) of maternal adherence to the Mediterranean diet during pregnancy and offspring cord blood DNA methylation in 2802 mother–child pairs from five cohorts. We calculated the relative Mediterranean diet (rMED) score with range 0–18 and an adjusted rMED excluding alcohol (rMEDp, range 0–16). DNA methylation was measured using Illumina 450K arrays. We used robust linear regression modelling adjusted for child sex, maternal education, age, smoking, body mass index, energy intake, batch, and cell types. We performed several functional analyses and examined the persistence of differential DNA methylation into childhood (4.5–7.8 y). rMEDp was associated with cord blood DNA methylation at cg23757341 (0.064% increase in DNA methylation per 1-point increase in the rMEDp score, SE = 0.011, P = 2.41 × 10−8). This cytosine–phosphate–guanine (CpG) site maps to WNT5B, associated with adipogenesis and glycaemic phenotypes. We did not identify associations with childhood gene expression, nor did we find enriched biological pathways. The association did not persist into childhood. In this meta-analysis, maternal adherence to the Mediterranean diet (excluding alcohol) during pregnancy was associated with cord blood DNA methylation level at cg23757341. Potential mediation of DNA methylation in associations with offspring health requires further study.
title: Humanized pertussis antibodies and uses thereof
Creators: name: Padlan, Eduardo A.
name: Maynard, Jennifer A.
name: Nguyen, Annalee
name: Wagner, Ellen
Publisher: name: United States Patent and Trademark Office
Year: 2016
Subjects: subject: A61K39/40
subject: A61K2039/507
subject: C07K16/1225
subject: C07K2317/24
subject: C07K2317/76
subject: C07K2317/92
subject: C07K2317/94
subject: No longer published

description: The present invention relates to humanized antibodies which bind the pertussis toxin protein and their use as therapeutic agents. In particular, the present invention is directed to improved humanized 1B7 and 11E6 antibodies which bind the pertussis toxin protein.
OXTR-mediated signaling in astrocytes contributes to anxiolysis
Creators: name: Meinung, Carl-Philipp
name: Boi, Laura
name: Pandamooz, Sareh
name: Mazaud, David
name: Ghézali, Grégory
name: Rouach, Nathalie
name: Neumann, Inga D.
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: 500 Naturwissenschaften
subject: 590 Tiere (Zoologie)

description: Astrocytes are an indispensable part of signal processing within the mammalian brain. Thus, the mode of action of a neuropeptide such as oxytocin (OXT) can only be fully understood considering this integral part of the CNS. Here, we show that OXT regulates astrocytic gene expression, intracellular signaling and specific proteins both in vitro and in vivo. This translates into rapid regulation of astroglial structural and functional properties including cytoskeletal plasticity, coverage of synapses and gap-junction coupling. At the molecular level, we identify the previously undescribed Sp1-Gem signaling cascade as the key driver for these cell type-specific OXT effects. Finally at the behavioral level, we found in vivo that OXT requires astrocytes to exert its well described anxiolytic properties within the hypothalamic paraventricular nucleus. Thus, our study points to OXT receptor-expressing astrocytes as a critical component of the brain OXT system.
Additional file 5: of Protocol: genetic transformation of the fern Ceratopteris richardii through microparticle bombardment
Creators: name: Plackett, Andrew
name: Rabbinowitsch, Ester
name: Langdale, Jane
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology

description: Evaluation of callogenic hormone treatments. Comparison of two hormone treatments (BAPÂ +Â IBA vs. BAP only) on callus maintenance and callus transformation efficiency.
Maternal Diet Quality During Pregnancy and Offspring Hepatic Fat in Early Childhood: The Healthy Start Study
Creators: name: Moore, B.F
name: Starling, A.P
name: Sauder, K.A
name: Küpers, L.K
name: Perng, W
name: Cohen, C.C
name: Shankar, K
name: Hébert, J.R
name: Sundaram, S.S
name: Friedman, C
name: Felix, J.F
name: Shapiro, A.L.B
name: Dabelea, D
name: Shivappa, N
name: Scherzinger, A
Publisher: name: Elsevier B.V.
Year: 2023

description: Background: Overnutrition in utero may increase offspring risk of nonalcoholic fatty liver disease (NAFLD), but the specific contribution of maternal diet quality during pregnancy to this association remains understudied in humans. Objectives: This study aimed to examine the associations of maternal diet quality during pregnancy with offspring hepatic fat in early childhood (median: 5 y old, range: 4–8 y old). Methods: Data were from 278 mother–child pairs in the longitudinal, Colorado-based Healthy Start Study. Multiple 24-h recalls were collected from mothers during pregnancy on a monthly basis (median: 3 recalls, range: 1–8 recalls starting after enrollment), and used to estimate maternal usual nutrient intakes and dietary pattern scores [Healthy Eating Index-2010 (HEI-2010), Dietary Inflammatory Index (DII), and Relative Mediterranean Diet Score (rMED)]. Offspring hepatic fat was measured in early childhood by MRI. Associations of maternal dietary predictors during pregnancy with offspring log-transformed hepatic fat were assessed using linear regression models adjusted for offspring demographics, maternal/perinatal confounders, and maternal total energy intake. Results: Higher maternal fiber intake and rMED scores during pregnancy were associated with lower offspring hepatic fat in early childhood in fully adjusted models [Back-transformed β (95% CI): 0.82 (0.72, 0.94) per 5 g/1000 kcal fiber; 0.93 (0.88, 0.99) per 1 SD for rMED]. In contrast, higher maternal total sugar and added sugar intakes, and DII scores were associated with higher offspring hepatic fat [Back-transformed β (95% CI): 1.18 (1.05, 1.32) per 5% kcal/d added sugar; 1.08 (0.99, 1.18) per 1 SD for DII]. Analyses of dietary pattern subcomponents also revealed that lower maternal intakes of green vegetables and legumes and higher intake of “empty calories” were associated with higher offspring hepatic fat in early childhood. Conclusions: Poorer maternal diet quality during pregnancy was associated with greater offspring susceptibility to hepatic fat in early childhood. Our findings provide insights into potential perinatal targets for the primordial prevention of pediatric NAFLD.
Stable accumulation of human ribosomal proteins SA, S2, S3, S4X, S6, S7 in rabbit reticulocyte cell-free expression system
Creators: name: Neuheisel, Mary Louisa
name: Streit, Julia
Publisher: name: Digital Repository at the University of Maryland
Year: 2024
Subjects: First-Year Innovation and Research Experience (FIRE) Cell Ex
Human ribosomal proteins
Cell-free mammalian expression system
post-translational modifications

description: Mutations in human ribosomal proteins (RPs) contribute to severe, tissue-specific pathologies, indicating roles that extend beyond protein translation. RPSA is associated with pancreatic cell migration and congenital asplenia, while RPS3, RPS4X, and RPS7 are linked to Diamond-Blackfan anemia (DBA). While we understand the nucleolar assembly of RPs, the cytoplasmic events preceding RP translocation into the nucleus remain unclear. This work investigated the expression and posttranslational modifications (PTMs) of human RPSA, RPS2, RPS3, RPS4X, RPS6, and RPS7 using Rabbit Reticulocyte Lysate (RRL), an enucleated cell-free system that allows the study of cytosolic modifications crucial for RP stability. We conducted coupled transcription/translation experiments with Western blot analyses and immunoprecipitations with anti-FLAG antibodies and magnetic beads to analyze RP expression and cytosolic PTMs. Our results demonstrated the robust and stable expression of RPs, with distinct abundance and stability among different proteins despite expression from the same promoter under identical conditions. RPSA, RPS3, and RPS6 exhibited a molecular weight of approximately 8-10 kDa higher than predicted, suggesting PTM with a peptide. We also detected the presence of enzymes for O-GlcNAc modification within the RRL system. Treatment with TMG, an O-GlcNAcase inhibitor, resulted in increased O-GlcNAcylation levels. We propose that the RRL system is an invaluable tool for probing the roles of PTMs in the extraribosomal activity of RPs within the cytoplasm, representing a relevant and accessible model to deepen our understanding of ribosomopathies and their future therapeutic interventions.
title: OCT using spectrally resolved bandwidth
Creators: name: Feldman, Marc D.
name: Milner, Thomas E.
name: Grant, Robert
name: Oh, Jung-Hwan
name: Kim, Ji Hoon
name: Kumar, Karthik
name: Chen, Shaochen
name: Han, Li-Hsin
name: Kim, Eunha
name: Kemp, Nathaniel J.
name: Condit, Jonathan C.
Publisher: name: United States Patent and Trademark Office
Year: 2016
Subjects: subject: A61B5/0073
subject: A61B1/00096
subject: A61B1/00167
subject: A61B1/00172
subject: A61B5/0066
subject: A61B5/0084
subject: A61B5/6852
subject: No longer published

description: The embodiments disclosed herein is a system for optical coherence tomographic imaging of turbid (i.e., scattering) materials utilizing multiple channels of information. The multiple channels of information may encompass spatial, angle, spectral and polarization domains. More specifically, the embodiments disclosed herein is related to methods and apparatus for utilizing optical sources, systems or receivers capable of providing (source), processing (system) or recording (receiver) a multiplicity of channels of spectral information for optical coherence tomographic imaging of turbid materials. In these methods and apparatus the multiplicity of channels of spectral information that can be provided by the source, processed by the system, or recorded by the receiver are used to convey simultaneously spatial, spectral or polarimetric information relating to the turbid material being imaged tomographically. The multichannel optical coherence tomographic methods can be incorporated into an endoscopic probe for imaging a patient.
title: "Il sonno di Gesù", Fontana Lavinia, inv. 437 (ITA/EN)
title: Scheda catalogo digitale Borghese
titleType: AlternativeTitle
Creators: name: Iommelli, Antonio
name: Galleria Borghese
Publisher: name: Galleria Borghese
Year: 2024

description: Pubblicazione delle schede delle opere conservate nel museo ed estratte dal catalogo digitale di Galleria Borghese, nelle due versioni esistenti online, in italiano e inglese.

Collegamento al catalogo digitale:

ITA: https://www.collezionegalleriaborghese.it/

EN: https://www.collezionegalleriaborghese.it/en
title: Altering temperature in a mammalian body
Creators: name: Diller, Kenneth R.
name: Hensley, Daniel W.
name: Diller, Timothy T.
Publisher: name: United States Patent and Trademark Office
Year: 2017
Subjects: subject: A61F7/08
subject: A61F7/00
subject: A61F7/03
subject: A61F2007/0011
subject: A61F2007/0024
subject: A61F2007/0036
subject: A61F2007/0045
subject: A61F2007/0054
subject: A61F2007/0056
subject: A61F2007/0071
subject: A61F2007/0093
subject: A61F2007/0225
subject: A61F2007/0239
subject: A61N5/0625
subject: A61N5/1031
subject: A61N7/00
subject: No longer published

description: The present application relates to systems and methods for altering temperature in a mammalian body. Optionally, the systems and methods can be used to lower or raise core body temperature of a mammalian subject. Optionally, the systems and methods can be used to lower or raise the temperature of glabrous skin of a mammalian subject.
Expressing Human Ribosomal Proteins S20 and S26 in Modified E.coli (BL21) Cells
Creators: name: Lee, Maia
name: Quenano, Erika
name: Owen, Jennifer
name: Ngouba, Andrea
name: Zahniser, Hannah
name: Tafesh, Talah
name: Ofoegbu, Stacie
name: Weber, Louis
Publisher: name: Digital Repository at the University of Maryland
Year: 2024
Subjects: First-Year Innovation & Research Experience

description: Ribosomes are fundamental in creating proteins that contribute to the proper functioning of cellular processes. Thus, ribosome biogenesis must occur with integrity by appropriately expressing ribosomal proteins (RPs). Mutations in the genes of human RPS20 and RPS26 have been linked to disruption in the translation machinery and anomalies in the production of red blood cells, leading to diseases such as Diamond-Blackfan Anemia. To develop our understanding of the role of mutations in human RPS20 and RPS26, we performed ligase-independent cloning of their coding sequence into pNIC28-Bsa4 and pNH-TrxT and transformed these plasmids into a BL21 E. coli expression system. IPTG induction was used to determine conditions necessary to maximize the expression of soluble RPS20 and RPS26. After SDS-PAGE, Coomassie staining showed successful expression of RPS26 in response to IPTG induction, whereas RPS20 was produced regardless of IPTG presence. Human RPs expressed in bacteria are often purified from insoluble inclusion bodies; thus, determining the conditions for maximal solubility provides an optimal strategy for studying fusion proteins. Future research on the effects of the overexpression of RPS20 and RPS26 on human cell growth and viability will expand our understanding of the complex mechanisms of human ribosome biogenesis and its role in disease.
title: Corrosion detection sensor embedded within a concrete structure with a diffusion layer placed over the sacrificial transducer
Creators: name: Neikirk, Dean P.
name: Pasupathy, Praveenkumar
name: Wood, Sharon L.
name: Yosef, Ali Abu
Publisher: name: United States Patent and Trademark Office
Year: 2017
Subjects: subject: G01N27/021
subject: G01N17/04
subject: G01N33/383
subject: No longer published

description: A corrosion detection sensor embedded within a concrete structure. The sensor includes a hermetically sealed resonant circuit that is a resistor-inductor-capacitor (RLC) circuit. The sensor further includes a sacrificial transducer that is inductively or capacitively coupled to the resonant circuit, where the sacrificial transducer is exposed to an environment outside the sensor to monitor corrosion of steel reinforcement in the concrete structure. Additionally, the sensor includes a protective cementitious housing surrounding the resonant circuit and the sacrificial transducer. The sensor further includes a diffusion layer placed over the sacrificial transducer, where the diffusion layer enables a dispersion of a chemical species over the sacrificial transducer. In this manner, a more uniform distribution of the chemical species over the surface of the sacrificial transducer mitigating the localized corrosion is ensured. Furthermore, such a design is less susceptible to false positives.
Additional file 2: of Protocol: genetic transformation of the fern Ceratopteris richardii through microparticle bombardment
Creators: name: Plackett, Andrew
name: Rabbinowitsch, Ester
name: Langdale, Jane
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: G-418 selection conditions for C. richardii. Kill curves demonstrating the necessary concentration of G-418 antibiotic needed for selection of C. richardii callus, gametophytes and sporophytes.
Wood treatment method
Creators: name: Seifried, Udo
name: Mayer, Ingo
name: Volkmer, Thomas
name: Canoine, Benoît
name: Clerc, Gaspard
name: Buividé, Indre
name: Jäger, Elena
name: Pichelin, Frédéric
Publisher: name: WIPO / PCT
Year: 2019

description: The invention relates to a method for treating at least one part made of wood comprising: - A) an impregnation phase for impregnating the part with at least one colouring agent; - B) a steaming phase comprising heating said part in the presence of saturated steam; - C) a densifying phase comprising: i) compressing said part by exerting a first pressure at a first temperature then a second pressure at a second temperature, the second temperature and the second pressure being respectively lower than the first temperature and the first pressure.
Cloning and Expression of Human RPS24 into E.coli and the HEK293 Cell Line
Creators: name: Merrifield, Katherine
name: Apgar, Sofia
name: Whitney, Jessica
name: Argueta, Vicky
Publisher: name: Digital Repository at the University of Maryland
Year: 2024
Subjects: First-Year Innovation and Research Experience

description: Ribosome biogenesis is the process of constructing ribosomes and requires ribosomal RNA, ribosomal proteins (RPs), and assembly factors. The products of eukaryotic ribosome biogenesis are the large 60S subunit and the small 40S subunit, of which RPS24 is crucial in its formation. In addition to its translational roles, RPS24 is associated with regulating cell growth and proliferation, apoptosis, and DNA damage response. We hypothesize that the extra-ribosomal functions of RPS24 are impacted by its post-translational modifications (PTMs). To elucidate the functions of these PTMs, the coding sequence of human RPS24 was cloned into pNH-TrxT and pNIC28-Bsa4 bacterial expression vectors via ligase-independent cloning. The recombinant plasmids were then transformed into BL21 E.coli cells, and initial trials were conducted to optimize growth and expression conditions for the two transformed strains. Protein expression was determined using SDS-PAGE and Coomassie staining, the results of which indicated moderate levels of the RPS24 fusion protein in cells transformed with both the recombinant plasmids. RPS24 expression was observed without IPTG induction, indicating leaky expression. In parallel experiments, we investigated the overexpression of RPS24 in HEK293 cells from the plasmid pcDNA3.1(C)DYK, and successful transfection was confirmed by SDS-PAGE and Western Blot analysis. We aim to investigate the role of RPS24 PTMs in cell proliferation and viability under various stress conditions to evaluate their impact on tumor development.
title: Underwater noise abatement panel and resonator structure
Creators: name: Lee, Kevin M.
name: Wochner, Mark S.
name: Wilson, Preston
name: Mendez Martinez, Hector L.
Publisher: name: United States Patent and Trademark Office
Year: 2017
Subjects: subject: G10K11/172
subject: G10K2200/11
subject: No longer published

description: A system for reducing noise emissions in underwater environments is presented. The system can be extended to applications in any two-fluid environments where one fluid (gas) is contained in an enclosed resonator volume connected to the outside environment at an open end of the resonator body. The resonators act as gas-containing (e.g., air) Helmholtz resonators constructed into solid panels that are submerged in the fluid medium (e.g., sea water) in the vicinity of a noise generating source. The oscillations of the trapped air volume in the resonators causes reduction of certain noise energy and a general reduction in the transmitted noise in the environment of the system.
Wege in die Ernährungszukunft der Schweiz: Leitfaden zu den grössten Hebeln und politischen Pfaden für ein nachhaltiges Ernährungssystem
Creators: name: Fesenfeld, Lukas
name: Mann, Stefan
name: Meier, Matthias
name: Nemecek, Thomas
name: Scharrer, Bettina
name: Bornemann, Basil
name: Brombach, Christine
name: Beretta, Claudio
name: Bürgi, Elisabeth
name: Grabs, Janina
name: Ingold, Karin
name: Jeanneret, Philippe
name: Kisling, Sol
name: Lieberherr, Eva
name: Müller, Adrian
name: Pfister, Stephan
name: Schader, Christian
name: Schönberg, Sonja
name: Sonnevelt, Martijn
name: Barjolle, Dominique
name: Boivin, Pascal
name: Brunner, Thomas
name: Contzen, Sandra
name: Espa, Ilaria
name: Estève, Magali
name: Forney, Jérémie
name: Häberli, Christian
name: Hediger, Werner
name: Kopainsky, Birgit
name: Lehmann, Bernhard
name: Mack, Gabriele
name: Markoni, Evelyn
name: Meier, Beat
name: Paccaud, Fred
name: Rohmann, Sabine
name: Schindler, Magdalena
name: Schwab, Christian Nils
name: Tribaldos, Theresa
name: Waibel, Piera
name: Zähringer, Julie
Publisher: name: SDSN Schweiz
Year: 2023

description: Die Ernährungssicherheit ist gefährdet. Kriege, Pandemien, Klimawandel und das Schwinden der Biodiversität bedrohen auch die Versorgung der Schweiz. Als international vernetztes Land ist die Schweiz sowohl für die Versorgungssicherheit als auch als Wirtschaftsstandort auf weltweit funktionierende Ökosysteme und stabile Lieferketten angewiesen. Gleichzeitig ist das heutige Ernährungssystem treibende Kraft solcher Krisen. Es überschreitet die Belastbarkeitsgrenzen der Erde, verursacht unter anderem weltweit rund 30 Prozent der Treibhausgasemissionen und ist ein entscheidender Faktor für das Schwinden der Artenvielfalt. Auch die erhöhten Pandemierisiken und wachsende soziale Unruhen haben einen grossen Einfluss darauf, wie wir derzeit Lebensmittel produzieren, verarbeiten, verteilen und konsumieren.
Additional file 1: of Caregiving in ALS â   a mixed methods approach to the study of Burden
Creators: name: Galvin, Miriam
name: Corr, Bernie
name: Caoifa Madden
name: Mays, Iain
name: McQuillan, Regina
name: Timonen, Virpi
name: Staines, Anthony
name: Hardiman, Orla
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Extracts from semi-structured interview guide and standardised questionnaires. (DOCX 16Â kb)
Prenatal exposure to ambient air pollution and traffic and indicators of adiposity in early childhood: the Healthy Start study
Creators: name: Martenies, S.E
name: Adgate, J.L
name: Starling, A.P
name: Dabelea, D
name: Peel, J.L
name: Magzamen, S
name: Bloemsma, L.D
name: Allshouse, W.B
name: Thomas, D.S.K
Publisher: name: Springer Nature
Year: 2022

description: Background: Prenatal exposure to ambient air pollution and traffic have been related to a lower birth weight and may be associated with greater adiposity in childhood. We aimed to examine associations of maternal exposure to ambient air pollution and traffic during pregnancy with indicators of adiposity in early childhood. Methods: We included 738 participants of the Colorado-based Healthy Start study whose height, weight, waist circumference and/or fat mass were measured at age 4–6 years. We estimated residential exposure to ambient concentrations of fine particulate matter (PM2.5) and ozone (O3) averaged by trimester and throughout pregnancy via inverse distance-weighted interpolation of central site monitoring data. We assessed the distance to the nearest major roadway and traffic density in multiple buffers surrounding the participants’ homes. Associations of prenatal exposure to air pollution and traffic with overweight, waist circumference, percent fat mass and fat mass index (FMI) were assessed by logistic and linear regression. Results: Associations of exposure to PM2.5 and O3 at the residential address during pregnancy with percent fat mass and FMI at age 4–6 years were inconsistent across trimesters. For example, second trimester PM2.5 was associated with a higher percent fat mass (adjusted difference 0.70% [95% CI 0.05, 1.35%] per interquartile range (IQR; 1.3 µg/m3) increase), while third trimester PM2.5 was associated with a lower percent fat mass (adjusted difference −1.17% [95% CI −1.84, −0.50%] per IQR (1.3 µg/m3) increase). Residential proximity to a highway during pregnancy was associated with higher odds of being overweight at age 4–6 years. We observed no associations of prenatal exposure to PM2.5 and O3 with overweight and waist circumference. Conclusions: We found limited evidence of associations of prenatal exposure to ambient PM2.5 and O3 with indicators of adiposity at age 4–6 years. Suggestive relationships between residential proximity to a highway during pregnancy and greater adiposity merit further investigation.
title: High energy density aluminum battery
Creators: name: Brown, Gilbert M.
name: McIntyre, Timothy J.
name: Dudney, Nancy J.
name: Sun, Xiaoguang
name: Manthiram, Arumugam
name: Dai, Sheng
name: Paranthaman, Mariappan Parans
name: Liu, Hansan
Publisher: name: United States Patent and Trademark Office
Year: 2016
Subjects: subject: H01M10/054
subject: H01M4/38
subject: H01M4/463
subject: H01M4/50
subject: H01M10/0525
subject: H01M10/056
subject: H01M10/0568
subject: H01M10/0569
subject: H01M6/16
subject: H01M10/058
subject: H01M2300/0028
subject: Y02E60/122
subject: Y10T29/49108
subject: No longer published

description: Compositions and methods of making are provided for a high energy density aluminum battery. The battery comprises an anode comprising aluminum metal. The battery further comprises a cathode comprising a material capable of intercalating aluminum or lithium ions during a discharge cycle and deintercalating the aluminum or lithium ions during a charge cycle. The battery further comprises an electrolyte capable of supporting reversible deposition and stripping of aluminum at the anode, and reversible intercalation and deintercalation of aluminum or lithium at the cathode.
Ambient air pollution during pregnancy and cardiometabolic biomarkers in cord blood
Creators: name: Magzamen, S
name: Thomas, D.S.K
name: Friedman, C
name: Bloemsma, L.D
name: Starling, A.P
name: Martenies, S.E
name: Peel, J.L
name: Allshouse, W.B
name: Dabelea, D
name: Adgate, J.L
Publisher: name: Wolters Kluwer Health
Year: 2022

description: Background/Objectives: Prenatal air pollution exposure has been associated with adverse childhood cardiometabolic outcomes. It is unknown whether evidence of metabolic disruption associated with air pollution is identifiable at birth. We examined exposure to prenatal ambient air pollution and cord blood cardiometabolic biomarkers among 812 mother-infant pairs in the Healthy Start study. Methods: Using inverse-distance-weighted interpolation of ambient concentrations obtained from stationary monitors, we estimated daily particulate matter ≤2.5 micrometers PM2.5 and ozone O3 concentrations at participant residences. Daily estimates were averaged by trimester, full-pregnancy, and the 7 and 30 days prior to delivery. Associations of air pollution with the following cord blood biomarkers were estimated via multivariable linear regression: glucose, insulin, glucose/insulin ratio GIR, leptin, high-density lipoprotein HDL cholesterol, non-HDL cholesterol, free fatty acids, and triglycerides. Results: In this Denver-based cohort, PM2.5 concentrations were lower than in many US urban areas, but O3 concentrations regularly exceeded federal air quality standards. Higher O3 concentrations during pregnancy were consistently associated with higher insulin and lower GIR in cord blood. For example, an interquartile range increase in full pregnancy O3 6.3 parts per billion [ppb] was associated with 0.13 log-IU/ml 95% confidence interval [CI] = 0.04, 0.22 higher cord blood insulin, after adjusting for PM2.5 and other confounders. We found positive, but generally nonsignificant, associations between PM2.5 and leptin and isolated associations between pollutants during certain exposure periods and lipids. Conclusions: In this cohort with moderately high O3 exposure, prenatal concentrations of O3 were positively associated with cord blood insulin. Future studies should examine the implications for offspring long-term health.
Additional file 4: of Protocol: genetic transformation of the fern Ceratopteris richardii through microparticle bombardment
Creators: name: Plackett, Andrew
name: Rabbinowitsch, Ester
name: Langdale, Jane
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biophysics
subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy
subject: Plant Biology
subject: Computational Biology

description: Culturing protocols for C. richardii. Protocols for the preparation and growth of C. richardii in sterile tissue culture and on soil.
AITANA MOVEC: Report of dissemination actions of project results
Creators: name: ITI
Publisher: name: Zenodo
Year: 2022
Subjects: AITANA MOVEC
2021
ARTIFICIAL INTELLIGENCE
MLOps
AITANA

description: AITANA MOdel VErsion Control: Creating a complete development and production environment with version control and MLOps tools in a simple and intuitive way.

This document describes the work carried out and the validation of the architecture developed, in collaboration with the Hospital Universitario La Fe de Valencia.

 
description: AITANA-MOVEC. Project funded by the Valencian Institute of Business Competitiveness (IVACE) and European Union through the European Regional Development Fund (ERDF), within the public grant program adressed to Technological Institutes of the Valencian Community for the development of non-economic R&D projects carried out in cooperation with companies during 2021 with 103.469,80€. File number: IMDEEA/2021/80
Martenseya Shear 2021, new genus
Creators: name: Shear, William A.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Diplopoda
Chordeumatida
Caseyidae
Martenseya

description: Martenseya new genus
Type species. Martenseya minutocaeca n. sp.
Diagnosis. Distinct from all other caseyid genera in the lateral two metazonital setae set on a distinct swelling, and in the gonopods, which consist of two narrow coxites and lack flagellocoxites. Unlike all other species so far described, the third legs of Martenseya minutocaeca n. sp. do not have enlarged, elongated coxae. The type species is by far the smallest known caseyid, at 3.2 mm long in males. The two species of caseyid previously ranked as smallest, Metopiona sheari Gardner & Shelley, 1989 and Speoseya grahami Causey, 1963, at 8–10 mm long are two or three times larger than Martenseya minutocaeca n. sp.
Etymology. I am delighted to name this unusual new genus in honor of Prof. Dr. Jochen Martens, my esteemed friend and colleague, on the occasion of his 80th birthday. To avoid homonymy, the suffix − eya, as in Caseya and Speoseya, is added to the name. The name is feminine in gender.
Description. See below, as for the type and only known species, Martenseya minutocaeca n. sp.
Distribution. Presently known only from Marin County, California, USA.
Notes. The divergence from the general plan of the Caseyidae of the single included species mandates the establishment of the new genus. Martenseya minutocaeca n. sp. lacks long gonapophyses on the second legs, and the third legs, rather than having elongate coxae and reduced telopodites, are unmodified and exactly like the following legs. The tenth legs have coxae that are only slightly enlarged and lack lobes and processes.
The simple gonopods are not unlike those of Metopiona sheari Gardner & Shelley, 1989 in having only anterior and posterior angiocoxites (though quite different inn form), a large sternum, and no flagellocoxites. However, M. sheari has the typical pregonopodal leg modifications that are lacking in Martenseya n. gen. Metopiona sheari is easily twice the size of Martenseya minutocaeca n. sp., and has 10 ommatidia. The other known small caseyid is Speoseya grahami Causey, 1963 which is eyeless but even larger (10 mm) than M. grahami. I have studied the holotype male of S. grahami and found the gonopod pattern very close to that of Opiona, not at all similar to Metopiona or Martenseya n. gen. Finally, I have seen two species of another undescribed genus from Washington state in the size range of M. minutocaeca n. sp., but with two black ommatidia on each side of the head and a gonopod pattern that is completely different, again resembling that of Opiona.
description: Published as part of Shear, William A., 2021, Additions to the millipede family Caseyidae. II. Martenseya, a new genus of miniature, blind millipedes from California (Diplopoda, Chordeumatida Striariidea, Striarioidea, Caseyidae), pp. 108-113 in Zootaxa 4984 (1) on pages 110-111, DOI: 10.11646/zootaxa.4984.1.10, http://zenodo.org/record/4926688
title: Process-based approach for the detection of deep gas invading the surface
Creators: name: Romanak, Katherine
name: Bennett, Philip C.
Publisher: name: United States Patent and Trademark Office
Year: 2017
Subjects: subject: G01N33/24
subject: No longer published

description: The present invention includes a method for determining the level of deep gas in a near surface formation that includes: measuring CO2, O2, CH4, and N2 levels in percent by volume from one or more surface or near surface geological samples; adding the water vapor content to the measured CO2, O2, CH4, and N2 levels in percent by volume; normalizing the gas mixture to 100% by volume or 1 atmospheric total pressure; and determining the ratios of: O2 versus CO2 to distinguish in-situ vadose zone CO2 from exogenous deep leakage CO2; CO2 versus N2 to distinguish whether CO2 is being removed from the near surface formation or CO2 is added from an exogenous deep leakage input; or CO2 versus N2/O2 to determine the degree of oxygen influx, consumption, or both; wherein the ratios are indicative of natural in situ CO2 or CO2 from the exogenous deep leakage input.
Towards a Fairness Score for Machine Learning Training Data
Creators: name: Kurpicz-Briki, Mascha
Year: 2020

description: Digital ethics has become a more and more important topic, and is highly relevant also when it comes to machine learning. Biased training data (e.g. gender, racial bias, and more) can have dramatic consequences for the fairness of applications using machine learning models. When a model trained on biased data is used for smart decision making, unfair decisions might be taken. We therefore need a transparent and independent classification system, to measure the fairness of training data fed into machine learning algorithms.
title: Medical device identifier
Creators: name: Valvano, Jonathan W.
name: Pearce, John A.
name: Horton, Rodney P.
Publisher: name: United States Patent and Trademark Office
Year: 2017
Subjects: subject: A61B5/74
subject: A61B90/90
subject: A61N1/3718
subject: A61N1/37235
subject: A61N1/37252
subject: A61B1/00112
subject: A61B5/00
subject: A61B2562/08
subject: A61N1/3727
subject: A61N1/37288
subject: G06F19/00
subject: G06F17/40
subject: G06F19/3481
subject: G16H40/63
subject: H03M3/00
subject: H04W12/00
subject: H04B1/401
subject: H04L13/02
subject: H04M3/00
subject: No longer published

description: A medical device identifier can identify an implanted medical device. In one example arrangement, the medical device identifier sends electromagnetic signals to the implanted device according to one or more stored digitized waveforms. The device then senses any returned electromagnetic signals, and identifies the implanted device based on the returned electromagnetic signals. The medical device identifier may generate the electromagnetic signals from the stored digitized waveforms using an analog-to-digital converter, and may compare the returned electromagnetic signals with one or more stored digital templates corresponding to different device manufacturers. The comparison may be performed using cross correlation. In another aspect, a portal device includes an identification subsystem for identifying the provider of a medical device, and a communication subsystem for establishing two-way communication a call center servicing medical devices from an identified provider. The portal device may relay information between the medical device and the identified provider.
"Only a Demon in Her Shape": A Queer Positive Reading of Bram Stoker's Dracula
Creators: name: Swain, Kayla
Publisher: name: Maryland Shared Open Access Repository
Year: 2024
Subjects: Dracula
Queer theory
Oscar Wilde

description: Since Dracula embodies a lot of Queer stereotypes from the time and multiple members of Stoker’s band of heroes show signs of being closeted, many scholars have taken to reading Stoker’s heroes’ rejection of Dracula as a rejection of their Queer identities. The problem with such readings is that they tend to emphasis the groups’ acts of Queer shame without acknowledging the fact that they come to find love and acceptance among one another and so, resolve their fears, insecurities, and the self-hatred they feel as a result of being a Queer person living in late nineteenth century England. By acknowledging neither the acceptance the group receives from one another nor the resolution of their Queer shame, those who read Stoker’s horror novel through a Queer lens have repeatedly reached the conclusion that Dracula is symbolic of and or intended to represent Stoker’s heroes’ Queer desires and sentiment. All the while, another interpretation, one that acknowledges the groups’ acceptance of their Queer identities and paints Dracula as a symbol of the negative, monstrous image of the “homosexual” that tormented the Queer community in the aftermath of the 1885 Amendment and Oscar Wilde trials, has gone mostly unexplored and ignored. And that interpretation is what this paper explores.
title: Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications
Creators: name: Schmidt, Christine E.
name: Mayes, Sarah M.
Publisher: name: United States Patent and Trademark Office
Year: 2017
Subjects: subject: A61L31/041
subject: A61K31/192
subject: A61K31/195
subject: A61L31/145
subject: A61L31/148
subject: A61L31/16
subject: A61L2300/414
subject: A61L2300/43
subject: A61L2300/62
subject: C08L5/08
subject: C08L5/04
subject: No longer published

description: A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components.
Prenatal metal(loid) mixtures and birth weight for gestational age: A pooled analysis of three cohorts participating in the ECHO program
Creators: name: Meeker, J.D
name: Jackson, B.P
name: O'Connor, T.G
name: Madan, J.C
name: Environmental Influences on Child Health Outcomes
name: Garcia, E
name: Starling, A.P
name: Breton, C.V
name: Howe, C.G
name: Karagas, M.R
name: Farzan, S.F
name: Nozadi, S.S
name: Cordero, J.F
name: Alshawabkeh, A.N
name: Bastain, T.M
Publisher: name: Elsevier Ltd
Year: 2022

description: Background: A growing number of studies have identified both toxic and essential metals which influence fetal growth. However, most studies have conducted single-cohort analyses, which are often limited by narrow exposure ranges, and evaluated metals individually. The objective of the current study was to conduct an environmental mixture analysis of metal impacts on fetal growth, pooling data from three geographically and demographically diverse cohorts in the United States participating in the Environmental Influences on Child Health Outcomes program. Methods: The pooled sample (N = 1,002) included participants from the MADRES, NHBCS, and PROTECT cohorts. Associations between seven metals (antimony, cadmium, cobalt, mercury, molybdenum, nickel, tin) measured in maternal urine samples collected during pregnancy (median: 16.0 weeks gestation) and birth weight for gestational age z-scores (BW for GA) were investigated using Bayesian Kernel Machine Regression (BKMR). Models were also stratified by cohort and infant sex to investigate possible heterogeneity. Chromium and uranium concentrations fell below the limits of detection for most participants and were evaluated separately as binary variables using pooled linear regression models. Results: In the pooled BKMR analysis, antimony, mercury, and tin were inversely and linearly associated with BW for GA, while a positive linear association was identified for nickel. The inverse association between antimony and BW for GA was observed in both males and females and for all three cohorts but was strongest for MADRES, a predominantly low-income Hispanic cohort in Los Angeles. A reverse j-shaped association was identified between cobalt and BW for GA, which was driven by female infants. Pooled associations were null for cadmium, chromium, molybdenum, and uranium, and BKMR did not identify potential interactions between metal pairs. Conclusions: Findings suggest that antimony, an understudied metalloid, may adversely impact fetal growth. Cohort- and/or sex-dependent associations were identified for many of the metals, which merit additional investigation.
Health care users’ and pro-fessionals’ perspectives and experiences in fertility treatment in Switzerland – where do we stand and what do we need (HoPE).
Creators: name: Bernet, Madeleine
name: Soom Ammann, Eva
Year: 2022

description: Introduction: Infertility is a spreading phenomenon which is expected to gain further relevance, due to the ongoing trend to a higher age of primiparous women which has been observed in recent decades. From the age of 35 years, infertility increases because of the decreasing quality of the ovaries. Since 2019, fertility preservation has been a mandatory benefit of Swiss health insurance companies for patients with oncological diseases. This aspect together with a general trend towards an increased demand for consultations leads to a rising number of time intensive consultations in fertility clinics. Affected persons have special care needs in the context of fertility treatments, and nurses and midwives play a key role in the treatment process of patients and their families. Consequently, the subject described is also relevant to nursing science. Aim of the study: The planned study aims to collect and describe the perspectives, experiences, and needs of persons undergoing fertility treatment as well as professionals in this field (nurses, midwives, and physicians). Based on this, the current care situation in reproductive medicine will be discussed to formulate suggestions for adaptation. The implementing of a specialized nursing/midwifery role will be examined, and recommendations will be formulated. Methods: To comprehensively describe the present care situation and to identify adaptation needs, a mixed-methods research design will be applied, involving a scoping review, cross-sectional surveys, face-to-face qualitative interviews (individuals/couples), and focus groups (health care professionals). Relevance for research and practice: The study aims to identify challenges and gaps in a specific area of health care and helps to develop solutions and new concepts. The project sheds light on a patient group that receives rather little attention but is often considerably burdened. In addition, the project contributes to the promotion of interprofessional cooperation and should lead to an improvement in the quality of care.
Understanding the Concept of Race and Racial Discrimination in Latin America
Creators: name: Perez, Axel S. Barahona
Publisher: name: Maryland Shared Open Access Repository
Year: 2024
Subjects: Latin America
Racial Discrimination
Socioeconomic Inequality
Racial Democracy
Mestizaje

description: Latin America ranks highest in the world in markers of socio-economic inequality, as well as in the negative effects that inequality has on other realms of life, such as access to basic services, access to education and professional opportunities, political influence, and, in many countries, unfair treatment by police and the justice system. These factors of inequality affect the lives of millions of people in Latin America, mainly indigenous and Afro-descendant people. Thus, it is evident that discrimination and racism are a constituent part of the Latin American region. However, many Latin American countries have declared themselves as post-racial because of the multi-racial and multi-cultural characteristics of their population, arguing that racism and racial discrimination are not present in their body politics and society. This narrative is the result of the concept of mestizaje, the mixing of races, that was imposed on the populations during colonial times, and in the post-colonial period. The concepts of mestizaje and racial democracy were utilized by Latin American Elites as tools for the nation-building process of the newly formed nations. Consequently, after political and social processes of integration into Latin American society and identity, the concepts of race and racial discrimination are not considered social issues, and there is a denial regarding the existence of racism and discrimination in the Latin American region by the general public and governments.
MOESM2 of Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis
Creators: name: Chih-Ming Ho
name: Shih, Daniel
name: Chih-Chiang Hsiao
name: Shih-Hung Huang
name: Shwu-Fen Chang
name: Cheng, Wen-Fang
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 2: Table S2. Primer sequences used for MS-PCR.