cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
La expresión corporal en el mejoramiento de la comunicación asertiva a través de estrategias pedagógicas digitales- web en los estudiantes del grado 4 de la Institución Educativa El Quebradón Rio blanco Tolima.
Creators: name: Buenaventura Vargas, Yeimy Yicela
name: Cristancho Rivera, Yenny Patricia
name: González Suarez, Claudia Patricia
Publisher: name: Universidad de Cartagena
Year: 2023
Subjects: subject: Herramientas tecnológicas
subject: Comunicación - Técnicas
subject: Expresión corporal - Enseñanza

description: Este proyecto tiene como objeto la expresión corporal y la tecnología como conceptos importantes ya que son elementos trascendentales para lograr una comunicación efectiva y mejorar nuestras relaciones interpersonales; por lo tanto, es importante prestar atención a ambas para lograr una comunicación clara, respetuosa y efectiva y todo esto con la tecnología como principal aliada para incentivar al aprendizaje ya que resulta muy valioso implementar propuestas de este tipo, porque se puede generar un impacto positivo dentro de las demás instituciones educativas del municipio motivándolas a motivándolas a la realización otros proyectos similares con el fin de continuar y fortalecer educación tecnológica de los estudiantes y sus entornos educativos. Para finalizar es importante destacar que, a partir de este proyecto, se presentaron nuevas oportunidades de investigación, emprendimientos y propuestas que satisficieron las necesidades y motivaciones de los estudiantes en diferentes campos de su formación integral fortaleciendo sus conocimientos para lograran obtener herramientas pedagógicas y sociales para enfrentar, interactuar y contribuir a la sociedad actual con criterio y conocimiento de causa.
Algebraic families of Galois representations and potentially semi-stable pseudodeformation rings
Creators: name: Wang-Erickson, Carl
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 11F80 (Primary) 11S20, 14D15, 14L24 (Secondary)

description: We construct and study the moduli of continuous representations of a profinite group with integral $p$-adic coefficients. We present this moduli space over the moduli space of continuous pseudorepresentations and show that this morphism is algebraizable. When this profinite group is the absolute Galois group of a $p$-adic local field, we show that these moduli spaces admit Zariski-closed loci cutting out Galois representations that are potentially semi-stable with bounded Hodge-Tate weights and a given Hodge and Galois type. As a consequence, we show that these loci descend to the universal deformation ring of the corresponding pseudorepresentation.
description: Numbering changed and typos corrected to match published version. 59 pages
Additional file 1 of The effectiveness of online team-based learning in introduction to medical ethics education for medical students at a medical college of Nepal: a pilot study
Creators: name: Subedi, Nuwadatta
name: Hirachan, Neelu
name: Paudel, Sabita
name: Shrestha, Bijayata
name: Pradhan, Anju
name: Subedee, Anish
name: Li, Xiaodan
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Supplementary Material 1
Ultrastructural study of mode of entry of Chlamydia psittaci into L-929 cells.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: The entry of Chlamydia psittaci into L-929 cells was studied morphologically by transmission electron microscopy and quantitatively by a method that discriminates between attachment and uptake. Upon adsorption of 3H-labeled elementary bodies (EBs) to host cells at 4 degrees C, the EBs bound efficiently to the L-cell surface. Binding reached an equilibrium level of 55% in 3 h. Ultrastructural analysis revealed that EBs were bound preferentially to the tips and sides of microvilli at this temperature. The EBs were also observed in coated pits located at the bases of microvilli and along smooth surfaces of the host cell. No internalization was observed at 4 degrees C. When cells with prebound 3H-labeled EBs were warmed to 37 degrees C, the EBs rapidly became resistant to proteinase K removal (half time = 5 min), indicating ingested chlamydiae. At 37 degrees C, the EBs were internalized within tightly bound vesicles surrounded by an electron-dense coat of fibrillar material. EBs were also present in smooth-surfaced pits and vesicles of the host cell. Using alpha 2-macroglobulin coupled to colloidal gold (a known marker for receptor-mediated endocytosis), we observed that the entry of EBs into cells via coated pits was identical in appearance to the internalization of alpha 2-macroglobulin. Also, when the two ligands were mixed together, they could be seen within the same coated pits and were cointernalized within endocytic vesicles of the host cell. These results suggest that C. psittaci can enter nonprofessional phagocytic cells by a pathway which is similar to that of receptor-mediated endocytosis of many physiologically important macromolecules, bacterial toxins, and viruses.
A Mycoplasma genitalium protein resembling the Mycoplasma pneumoniae attachment protein.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: In previous studies with hyperimmune rabbit sera and monoclonal antibodies against the P1 protein of Mycoplasma pneumoniae, we obtained evidence of a shared antigenic determinant with a single protein of Mycoplasma genitalium. Because of biologic and morphologic similarities between these two human Mycoplasma species, attempts were made to characterize this cross-reacting protein of M. genitalium (designated MgPa). The protein was surface exposed and had an estimated molecular size of 140 kilodaltons. Electron microscopy with monoclonal antibodies produced against either MgPa or P1 demonstrated that MgPa is located over the surface of the terminal structure of M. genitalium which is covered by a nap layer. These immunologic and morphologic findings suggest that the MgPa protein of M. genitalium could be the counterpart of the P1 protein of M. pneumoniae.
Analysis of T-cell-dependent and -independent antigens of Rickettsia conorii with monoclonal antibodies.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: Four monoclonal antibodies from euthymic mice and two monoclonal antibodies from athymic mice were directed against antigens of Rickettsia conorii, as shown by both indirect immunofluorescence and an enzyme immunoassay. There was extensive cross-reactivity with other spotted fever group rickettsiae. Euthymic monoclonal antibodies 3-2 and 9-2 (immunoglobulin G2a [IgG2a]) and 27-10 (IgG1) distinctly outlined the acetone-fixed rickettsial surface, as determined by indirect immunofluorescence; only monoclonal antibody 3-2 reacted with the intact rickettsial surface, as determined by colloidal gold-protein A negative-stain electron microscopy. Athymic monoclonal antibodies 32-2 and 35-3 (IgM) and euthymic monoclonal antibody 31-15 (IgG3) all demonstrated an irregular, extrarickettsial morphology, as determined by immunofluorescence, and ultrastructural cell wall blebs that were readily shed from the rickettsial surface. Monoclonal antibody 3-2, the only antibody to confer protection in lethally challenged mice, reacted with a high-molecular-weight protein in Western immunoblots. Monoclonal antibodies 31-15, 32-2, and 35-3 reacted with a "ladder" of proteinase K-resistant, lipopolysaccharidelike antigens. None of the monoclonal antibodies stabilized the ultrastructural rickettsial slime layer, but both athymic and euthymic polyclonal antibodies to R. conorii did. This is, to the best of our knowledge, the first report of the production of monoclonal antibodies to R. conorii and their use for antigenic analysis.
Antigenic and structural differences among six proteins II expressed by a single strain of Neisseria gonorrhoeae.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: Gonococci express a family of related outer membrane proteins designated protein II (P.II), which undergo both phase and antigenic variation. Six P.II proteins have been identified in strain FA1090. We developed monoclonal antibodies specific for each P.II protein. Using these antibodies as probes, we purified the six different P.II proteins of this strain. Despite the relatedness of the proteins, we could not purify all of them by a single purification scheme. Four P.II proteins were purified by chromatofocusing, and the remaining two proteins were purified by hydrophobic interaction chromatography on phenyl-Sepharose. The N-terminal amino acid sequence of the proteins showed a high degree of sequence conservation. However, there was variability at specific amino acid residues, giving each P.II protein a unique N-terminal amino acid sequence. Thus P.II proteins of one strain differ among themselves not only in antigenic determinants and primary structure, but also in other characteristics affecting their properties in different chromatographic systems.
Changes in the cell surface properties of Treponema pallidum that occur during in vitro incubation of freshly extracted organisms.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: We previously reported that a number of Treponema pallidum membrane proteins appear to reside on the cell surface, since intact treponemes radiolabeled by overnight incubation in medium containing [35S]methionine bind immunoglobulin G (IgG) antibodies directed against these proteins. In the present study, it was found that freshly extracted organisms radiolabeled in vitro for only 2 h inefficiently bound IgG antibodies directed against just two proteins of molecular weights 40,000 and 34,000. An in vitro incubation period of greater than 8 h was required before IgG antibodies present in rabbit syphilitic serum could recognize additional protein antigens on the cell surface. Treatment of aged treponemes, but not freshly extracted organisms, with 0.04% sodium dodecyl sulfate selectively removed a membranous layer from the treponemal surface. Only three treponemal proteins were found associated with this structure, including the same 40,000- and 34,000-molecular-weight proteins mentioned above. These two proteins most likely represent endoflagellar subunits, since they were precipitated with rabbit antisera prepared against purified endoflagellar subunits of the cultivable treponemal strain Treponema phagedenis. Further evidence also was obtained that cells of T. pallidum actively secrete into their extracellular environment a unique class of low-molecular-weight proteins.
Additional file 1 of Patterns of change in obesity indices and other cardiometabolic risk factors before the diagnosis of type 2 diabetes: two decades follow-up of the Tehran lipid and glucose study
Creators: name: Koohi, Fatemeh
name: Ahmadi, Nooshin
name: Azizi, Fereidoun
name: Khalili, Davood
name: Valizadeh, Majid
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Additional file 1: FigureS1. Flowchart of the participants included in the current study.
Profinite Techniques for Probabilistic Automata and the Markov Monoid Algorithm
Creators: name: Fijalkow, Nathanaël
Publisher: name: arXiv
Year: 2015
Subjects: subject: Formal Languages and Automata Theory (cs.FL)
subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: We consider the value 1 problem for probabilistic automata over finite words: it asks whether a given probabilistic automaton accepts words with probability arbitrarily close to 1. This problem is known to be undecidable. However, different algorithms have been proposed to partially solve it; it has been recently shown that the Markov Monoid algorithm, based on algebra, is the most correct algorithm so far. The first contribution of this paper is to give a characterisation of the Markov Monoid algorithm. The second contribution is to develop a profinite theory for probabilistic automata, called the prostochastic theory. This new framework gives a topological account of the value 1 problem, which in this context is cast as an emptiness problem. The above characterisation is reformulated using the prostochastic theory, allowing us to give a simple and modular proof.
description: Conference version: STACS'2016, Symposium on Theoretical Aspects of Computer Science Journal version: TCS'2017, Theoretical Computer Science
Distribution of specific DNA sequences among pathogenic and commensal Neisseria species.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: Several traits, including pili and the outer membrane proteins P.II and H.8, have been associated with pathogenic Neisseria species. We examined several Neisseria species for DNA sequence homology to cloned pilin, P.II, and H.8 genes. Strains of Neisseria gonorrhoeae and N. meningitidis showed hybridization to all of these genes. Commensal strains showed little hybridization to any of these genes. Strains of N. lactamica and N. cinerea showed intermediate patterns of hybridization. Generally, organisms that expressed a given trait showed DNA homology to the corresponding cloned gene. However, we observed pili on some commensal strains that did not show hybridization to the cloned gonococcal pilin gene.
Fortalecimiento de la competencia de resolución de conflictos mediante una estrategia basada en el aprendizaje colaborativo con el uso de un blog interactivo como herramienta tecnológica en los estudiantes de grado décimo de la Institución Educativa Manuela Beltrán de Cartagena durante el periodo 2022- 2023.
Creators: name: Orozco Madarriaga, Xenia Celis
name: Cervantes Gonzalez, Jose Leonardo
name: Vallejo Ortega, Claudia Veronica
Publisher: name: Universidad de Cartagena
Year: 2023
Subjects: subject: Computadores - Aplicaciones
subject: Innovación pedagógica - Métodos de enseñanza
subject: Conflicto social

description: Este proyecto tiene como objeto implementar una estrategia pedagógica que a través del uso de un blog interactivo permita el fortalecimiento de la competencia de resolución de conflictos desde el aprendizaje colaborativo. Para ello se identificaron los tipos de conflictos que se presentan en el aula, a través de la observación y el diligenciamiento de un diario de campo y una encuesta dirigida hacia la población estudiantil. Los resultados encontrados permitieron la elaboración e implementación de la estrategia de aprendizaje colaborativo, a través de un blog educativo como herramienta tecnológica para compartir experiencias de los estudiantes sobre la resolución de conflictos. Con la implementación de esta propuesta se obtuvo cambios en los esquemas de trabajo, en los que se involucró a la comunidad educativa que se hizo participe de las diferentes actividades, logrando el aprendizaje de valores y el fortalecimiento de la competencia de resolución de conflictos en los estudiantes.
Effect of acetylation on arthropathic activity of group A streptococcal peptidoglycan-polysaccharide fragments.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: Purified group A streptococcal peptidoglycan-polysaccharide (PG-PS) fragments were either de-O-acylated, or acetylated and then de-O-acylated to yield N-acetylated PG-PS. Native PG-PS was poorly degraded, N-acetylated PG-PS was extensively degraded, and de-O-acylated PG-PS was only slightly degraded by hen egg white lysozyme. N-acetylated PG-PS was also extensively degraded by human lysozyme and partially degraded by rat serum or rat liver extract. After a single intraperitoneal injection of rats with a sterile, aqueous suspension, all PG-PS preparations induced acute arthritis. The acute arthritis induced by N-acetylated PG-PS was significantly more severe than that induced by native PG-PS; that induced by de-O-acylated PG-PS was of intermediate severity. After the acute reaction, rats injected with native PG-PS developed chronic relapsing erosive synovitis which remained severe for the duration of the experiment (83 days). In contrast, joint inflammation induced by N-acetylated PG-PS resolved within 6 weeks with little evidence of recurrent disease. Chronic arthritis induced by de-O-acylated PG-PS was of intermediate severity. In another assay of arthropathic activity, the arthritis in all rat ankle joints, which had been injected directly with native PG-PS, could be reactivated 3 weeks later by the intravenous injection of a small dose of PG. In contrast, only 50% of the joints initially injected with de-O-acylated PG-PS and none of the joints injected with N-acetylated PG-PS could be reactivated. These studies support the concepts that the resistance of PG-PS to muralytic digestion is crucial for chronic arthropathic activity and that the nature and degree of PG acetylation are important molecular determinants of the phlogistic activities of PG-PS polymers.
Additional file 3 of Patterns of change in obesity indices and other cardiometabolic risk factors before the diagnosis of type 2 diabetes: two decades follow-up of the Tehran lipid and glucose study
Creators: name: Koohi, Fatemeh
name: Ahmadi, Nooshin
name: Azizi, Fereidoun
name: Khalili, Davood
name: Valizadeh, Majid
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Additional file 3: TableS2. Parameter estimates for the best fitting 3-class cubic latent class growth mixture model fitted to the lipid profile data.
Diseño de una estrategia didáctica haciendo uso de la herramienta tecnológica Canva, para fortalecer las habilidades de comprensión lectora literal en estudiantes del grado cuarto de la Institución Educativa Ovidio Decroly.
Creators: name: Vacca Osorio, Egna Maryoli
name: Diaz Ramirez, Yandri Fausule
name: Rueda Hoyos, Isabel
Publisher: name: Universidad de Cartagena
Year: 2023
Subjects: subject: Herramientas virtuales
subject: Lectura - Aprendizaje
subject: Lectura - Enseñanza con ayuda de computadores

description: Este proyecto tiene como objeto fortalecer las habilidades de comprensión lectora en estudiantes del grado cuarto de la Institución Educativa Ovidio Decroly del municipio del Castillo en el departamento del Meta, cuyo enfoque de investigación fue la investigación cualitativa, por cuanto requirió investigar una situación problemática que aquejó a una comunidad educativa, el tipo de investigación seleccionado fue la Investigación Acción, porque permitió la intervención del investigador con fines de reducir el impacto negativo que tienen sobre las personas objeto de investigación; respecto al modelo, fue la Investigación Acción Pedagógica IAP, toda vez que se enfocaba en la transformación de la práctica del docente en los procesos educativos; La estrategia constó de 4 actividades entorno a la lectura de cuentos modernos las cuales se desarrollaron con el apoyo de las Tecnologías de Información y Comunicación - TIC, el acompañamiento y seguimiento de las docentes y padres de familia, para que los estudiantes cumplieran el objetivo de cada actividad y así fortalecer la comprensión lectora, lo cual se vio reflejado en el desempeño académico.
The_Philosophical_and_Mathematical_Implications_of_Division_by_Zero__in_Light_of_Einstein_s_Theory_of_Special_Relativity (3) (1).pdf
Creators: name: U ZAMAN, BUDEE
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 490401
subject: Algebra and number theory

description: The enigma of dividing zero by zero 00 has perplexed scholars acrossphilosophy, mathematics, and physics, remaining devoid of a clear-cut solution.This lingering conundrum leaves us in an unsatisfactory position,as there emerges a genuine necessity for such divisions, particularly inscenarios involving tensor components that are both set at zero. Thisarticle endeavors to grapple with this profound issue by leveraging theinsights of Einstein’s theory of special relativity. Surprisingly, when wewholeheartedly embrace the ramifications of this theory, it becomes evidentthat zero divided by zero must equate to one 00 = 1. Essentially, weare confronted with a pivotal decision: either embrace the feasibility anddefinition of dividing zero by zero, in accordance with Einstein’s theoryof special relativity, or reevaluate the integrity of this fundamental theoryitself. This exploration delves into the profound consequences arisingfrom this critical choice
Cristianizzazione della Mitologia Sardo-Corso-Atlantidea Da Poseidone a Satana
Creators: name: Usai, Luigi
Publisher: name: Zenodo
Year: 2024

description: Questo paper esplora la possibile cristianizzazione della mitologia sardo-corso-atlantidea, concentrandosi sulla trasformazione di Poseidone, dio dei mari e dell’acqua e della luce, in Satana, dio degli inferi, del fuoco e del buio. Si analizza come il Cristianesimo possa aver reinterpretato simboli e figure mitiche attraverso processi di sincretismo e distorsione, con l’obiettivo di sopprimere e trasformare culti preesistenti. Si discute l’influenza delle trasformazioni simbologiche e delle pratiche cristiane, analizzando l’eventuale cristianizzazione delle Domus de Janas e il ruolo delle figure mitologiche sardo-corso-atlantidee. Il paper presenta anche una riflessione sulle immagini generate tramite intelligenza artificiale per visualizzare la transizione simbolica da Poseidone a Satana e discute il contesto storico e culturale di tali cambiamenti.
Additional file 2 of Patterns of change in obesity indices and other cardiometabolic risk factors before the diagnosis of type 2 diabetes: two decades follow-up of the Tehran lipid and glucose study
Creators: name: Koohi, Fatemeh
name: Ahmadi, Nooshin
name: Azizi, Fereidoun
name: Khalili, Davood
name: Valizadeh, Majid
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Additional file 2: TableS1. Latent Class Growth Mixture Models (LCGMM) results of the model fitting process.
Effects of serum carrier proteins on the growth of pathogenic neisseriae with heme-bound iron.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: The pathogenic neisseriae can use free heme and hemoglobin as an essential source of iron (Fe) for growth in vitro, but it is unknown whether they can utilize heme bound to human hemopexin or to human serum albumin, or hemoglobin bound to haptoglobin. We found that neither Neisseria meningitidis nor Neisseria gonorrhoeae used bound heme, but bound hemoglobin was used as an Fe source by two meningococcal strains and one gonococcal strain. A second gonococcal strain, previously shown to use free hemoglobin poorly or not at all, also did not grow with hemoglobin-haptoglobin complex as an Fe source. These observations suggest that hemoglobin might act as an Fe source in vivo for many pathogenic neisseriae even when in complexed (bound) form, but heme probably would not support growth in vivo if bound to serum carrier proteins.
Fortalecimiento de la comprensión lectora para la resolución de problemas matemáticos a través de un blog digital en los estudiantes de séptimo grado de la Institución Educativa San José de Luruaco, Atlántico.
Creators: name: Ferrer De La Hoz, Yanina Patricia
name: Fontalvo Serje, Evelyn Paulet
name: Peña Galván, Eilen Carolina
Publisher: name: Universidad de Cartagena
Year: 2023
Subjects: subject: Computadores - Enseñanza
subject: Matemática - Aprendizaje
subject: Matemáticas - Enseñanza - Problemas, ejercicios, etc

description: Este proyecto tiene como objeto fortalecer la comprensión lectora en la resolución de problemas matemáticos a través de la implementación de un Blog digital en los estudiantes de séptimo grado de la Institución Educativa San José de Luruaco, Atlántico. En esta investigación la resolución y formulación de problemas matemáticos se considera un proceso importante en la enseñanza desde su entorno cotidiano generando conocimientos estratégicos. Esta investigación está enmarcada en un enfoque mixto (cualitativo, cuantitativo) y descriptiva, con procesos de investigación que se destacan en un sistema de recolección de datos dando a entender la realización de encuestas o cuestionarios en el que sirve de instrumento de medición conociendo sus variables y relaciones. Los resultados esperados de esta propuesta muestra que es posible adaptar una estrategia de apoyo como es el diseño de un blog que permitan al aprendiz mantener un estado mental propicio para el aprendizaje como una herramienta digital y pedagógica para favorecer el mejoramiento de la comprensión lectora en la resolución de problemas matemáticos en los estudiantes. Mediante el uso de estrategias es posible organizar, agrupar o clasificar el desarrollo de sus competencias y conocimientos de su aprendizaje.
Intermediate arithmetic operations on ordinal numbers
Creators: name: Altman, Harry
Publisher: name: arXiv
Year: 2015
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics
subject: 03E10

description: There are two well-known ways of doing arithmetic with ordinal numbers: the "ordinary" addition, multiplication, and exponentiation, which are defined by transfinite iteration; and the "natural" (or Hessenberg) addition and multiplication (denoted $\oplus$ and $\otimes$), each satisfying its own set of algebraic laws. In 1909, Jacobsthal considered a third, intermediate way of multiplying ordinals (denoted $\times$), defined by transfinite iteration of natural addition, as well as the notion of exponentiation defined by transfinite iteration of his multiplication, which we denote $α^{\timesβ}$. (Jacobsthal's multiplication was later rediscovered by Conway.) Jacobsthal showed these operations too obeyed algebraic laws. In this paper, we pick up where Jacobsthal left off by considering the notion of exponentiation obtained by transfinitely iterating natural multiplication instead; we will denote this $α^{\otimesβ}$. We show that $α^{\otimes(β\oplusγ)} = (α^{\otimesβ}) \otimes(α^{\otimesγ})$ and that $α^{\otimes(β\timesγ)}=(α^{\otimesβ})^{\otimesγ}$; note the use of Jacobsthal's multiplication in the latter. We also demonstrate the impossibility of defining a "natural exponentiation" satisfying reasonable algebraic laws.
description: 18 pages, 3 tables
Identification and purification of a recombinant Treponema pallidum basic membrane protein antigen expressed in Escherichia coli.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: A recombinant plasmid designated pLVS3 previously was described that harbored a 14-kilobase insert of Treponema pallidum genomic DNA. Escherichia coli maxicells programmed with this plasmid synthesized three treponemal protein antigens of molecular weights 39,000, 35,000, and 25,000 (39K, 35K, and 25K proteins, respectively). In this study, a detailed deletion analysis of pLVS3 demonstrated that the genetic information for all three protein antigens is contained within a 1.5-kilobase EcoRI-HpaI restriction fragment. The DNA sequence of this fragment revealed a single open reading frame of 361 codons that most likely encodes a signal peptide-bearing precursor to the 39K protein that can be transiently detected in E. coli maxicells. Evidence indicated that the 35K and 25K protein antigens are derivatives of the larger protein and are only produced in maxicells. A significant elevation in expression of the 39K treponemal protein antigen in E. coli was obtained by using the E. coli lpp and lac promoters and a genetic construction in which the signal peptide and first four residues of the "mature" 39K protein were replaced by six amino acids encoded by the vector. This hybrid protein exhibited an unusually high pI, which greatly facilitated its purification to homogeneity. By using antibody prepared against the hybrid protein, the native treponemal protein counterpart, also of molecular weight 39,000, was identified as a membrane component of T. pallidum. Since the native protein also exhibited a net positive charge, it has been designated the T. pallidum basic membrane protein.
Enseñanza de Ciencias Sociales a través del aprendizaje basado en problemas y mediante un objeto virtual de aprendizaje OVA con estudiantes de cuarto y quinto en aula rural multigrado de la Institución Educativa Técnica Agropecuaria de Desarrollo Rural sede “Manote bajo de Pauna en el departamento de Boyacá.
Creators: name: Cubillos Palomar, Libia
name: Rodríguez González, Milvia Azucena
name: Torres Villamil, Mónica Alexandra
Publisher: name: Universidad de Cartagena
Year: 2023
Subjects: subject: Herramientas virtuales
subject: Ciencias sociales - Enseñanza
subject: Ciencias sociales - Educación primaria

description: Este proyecto tiene como objeto fortalecer procesos de aprendizaje de Ciencias Sociales fundamentados en el Aprendizaje Basado en Problemas (ABP) y mediados por un Objeto Virtual de Aprendizaje (OVA), en estudiantes del grado cuarto y quinto de educación básica primaria de la Institución Educativa Técnica Agropecuaria de Desarrollo Rural sede “Manote Bajo de Pauna en el departamento de Boyacá. Es una investigación acción con enfoque cualitativo que sigue el modelo de la investigación acción pedagógica y elige el Aprendizaje Basado en Problemas como mediación pedagógica; se realizó con 15 estudiantes y cinco docentes que aportaron información importante para da respuesta a la pregunta formulada y alcanzar el objetivo planteado. Hecha la aplicación del OVA y con base en la evaluación realizada se concluye la importancia de vincular a los estudiantes de escuela rural multigrado a estrategias innovadoras que con incorporación de las TIC, contribuyen a mejorar procesos de enseñanza y aprendizaje en el área de Ciencias Sociales y con ello a optimizar la calidad educativa de niñas y niños de la ruralidad.
TDiff and Weyl Invariant Massive Spin-2: Linear Theory
Creators: name: Bonifacio, James
name: Ferreira, Pedro G.
name: Hinterbichler, Kurt
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We use Kaluza-Klein reduction to construct flat-space massive spin-2 Lagrangians based on a kinetic term that has local Weyl and transverse-diffeomorphism gauge symmetries in the massless limit. This yields Lagrangians describing a free massive spin 2 which differ from the usual Fierz-Pauli theory, but are physically equivalent to it. These Lagrangians require the use of auxiliary fields, which appear naturally from the higher-dimensional construction. We discuss how these Lagrangians are related to each other and to the Fierz-Pauli theory through Stückelberg transformations, gauge fixings, and field replacements, and we use this to generalize the construction to spin-2 fields on Einstein manifolds.
description: 37 pages, 2 figures. v3 some statements on equivalence corrected
Uso del video cuento y el aprendizaje basado en secuencias didácticas como estrategia para el fortalecimiento de la comprensión lectora en estudiantes de 5° grado de primaria de la Escuela Normal Superior del Quindío.
Creators: name: Quiroz Mendoza, Yarit De Jesús
name: Valencia Cifuentes, Eliana
name: Vásquez Daza, Víctor Eduardo
Publisher: name: Universidad de Cartagena
Year: 2023
Subjects: subject: Plataforma virtual
subject: Lectura - Aprendizaje
subject: Multimedia Interactiva en la Educación

description: Este proyecto tiene como objeto fortalecer la comprensión lectora de los estudiantes de grado quinto de la Escuela Normal Superior del Quindío, sede Ciudad Armenia. Para tal fin, se realizó una prueba diagnóstica del nivel de competencia lectora para determinar el estado inicial del grupo. Posteriormente, se diseñan y aplican los recursos educativos digitales y estrategias didácticas basadas en el Aprendizaje Basado en Secuencias Didácticas y el Aprendizaje Colaborativo. Luego, se evalúa el impacto de la estrategia a través de la aplicación de la prueba de conocimiento final. Lo anterior, dio como resultado que la competencia con menor nivel era la de carácter inferencial, por lo cual, se intervino mayormente en esta competencia. Luego de la evaluación final, se determinó que los estudiantes sí tuvieron un avance significativo en la comprensión lectora en general, pero que hubo mayor incidencia en la competencia inferencial, algo positivo para la investigación. Las conclusiones apuntan a destacar la importancia de la escuela como eje formador y base para el mejoramiento de la calidad educativa, así como el impacto de las nuevas tecnologías y los recursos digitales en los procesos de aprendizaje de los estudiantes. Además, la relevancia de crear y aplicar estrategias educativas innovadoras y creativas que faciliten la adquisición de conocimientos y el desarrollo de habilidades.
Nonoxidative antimicrobial effects of human polymorphonuclear leukocyte granule proteins on Chlamydia spp. in vitro.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: Proteins from isolated granules of human polymorphonuclear leukocytes were assessed for their nonoxidative microbicidal effect on chlamydiae by two different methods: a radioisotope assay for elementary body integrity and a biological assay for inclusion development. Crude granule extract, which consisted of a mixture of all granule proteins, caused a 20 to 30% decrease in infectivity and a 52% decrease in infectivity when incubated with Chlamydia psittaci CAL-10 and Chlamydia trachomatis serovar E, respectively. To define more specifically the components that were damaging to chlamydiae, crude granule extract was subjected to Sephadex G-75 column chromatography and isolated granule fractions were obtained. Only fractions containing lysozyme as the major component consistently caused reductions in infectivity of C. trachomatis elementary bodies. In contrast, fractions collected after the lysozyme fraction, containing proteins with molecular masses of 13,000 daltons or less, had detrimental effects on C. psittaci infectivity. Additional experiments using highly purified human polymorphonuclear leukocyte lysozyme confirmed its infectivity-reducing action upon C. trachomatis but not upon C. psittaci.
MOESM1 of Teledentistry as a novel pathway to improve dental health in school children: a research protocol for a randomised controlled trial
Creators: name: Estai, Mohamed
name: Yogesan Kanagasingam
name: Mehdizadeh, Maryam
name: Janardhan Vignarajan
name: Norman, Richard
name: Boyen Huang
name: Spallek, Heiko
name: Irving, Michelle
name: Arora, Amit
name: Estie Kruger
name: Tennant, Marc
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: SPIRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents*
Resistance to meningococcemia apparently conferred by anti-H.8 monoclonal antibody is due to contaminating endotoxin and not to specific immunoprotection.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: We evaluated the ability of a monoclonal antibody directed against the common H.8 antigen of pathogenic Neisseria sp. to confer passive protection against meningococcal disease in mice. The apparent protection conferred by antibody purified from tissue culture supernatant was actually the result of endotoxin contamination of buffers and tissue culture media. Endotoxin-free anti-H.8 antibody was not protective. The possibility of endotoxin contamination should be considered when evaluating immunity conferred by passively administered antibody in animal models.
Do improvements in clinical practice guidelines alter pregnancy outcomes in asthmatic women? A single-center retrospective cohort study
Creators: name: Robinson, J. L.
name: Gatford, K. L.
name: Hurst, C. P.
name: Clifton, V. L.
name: Morrison, J. L.
name: Stark, M. J.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Asthma occurs in ∼17% of Australian pregnancies and is associated with adverse perinatal outcomes, which worsen with poor asthma control. Consequently, the South Australian ‘Asthma in Pregnancy’ perinatal guidelines were revised in 2012 to address management according to severity. This study investigated if these revised guidelines reduced the impact of maternal asthma on risks of adverse perinatal outcomes before (Epoch 1, 2006–2011) and after the revision (Epoch 2, 2013–2018). Routinely collected perinatal and neonatal datasets from the Women’s and Children’s Hospital (Adelaide, Australia) were linked. Maternal asthma (prevalence:7.5%) was defined as asthma medication use or symptoms described to midwives. In imputation (n = 59131) and complete case datasets (n = 49594), analyses were conducted by inverse proportional weighting and multivariate logistic regression, accounting for confounders. Overall, maternal asthma was associated with increased risks of any antenatal corticosteroid treatment for threatened preterm birth (aOR 1.319, 95% CI 1.078–1.614), any Cesarean section (aOR 1.196, 95% CI 1.059–1.351), Cesarean section without labor (aOR 1.241, 95% CI 1.067–1.444), intrauterine growth restriction (IUGR, aOR 1.285, 95% CI 1.026–1.61), and small for gestational age (aOR 1.324, 95% CI 1.136–1.542). After guideline revision, asthma-associated risks of any Cesarean section (p < 0.001), any antenatal corticosteroids (p = 0.041), and small for gestational age (p = 0.050), but not IUGR and Cesarean section without labor, were reduced. Clinical practice guidelines based on the latest evidence do not guarantee clinical efficacy. Since adverse perinatal outcomes did not all improve, this work highlights the need to evaluate the ongoing impact of guidelines on clinical outcomes.
A pleiotropic iron-uptake mutant of Neisseria meningitidis lacks a 70-kilodalton iron-regulated protein.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1988

description: We isolated an iron-uptake mutant of Neisseria meningitidis M986-NCV-1 that was severely limited in the ability to use several sources of iron in the form of Fe3+. This mutant, FAM11, grew poorly or not at all with human transferrin (TF) or lactoferrin (LF) as the sole iron source in a defined medium but grew as well as wild-type meningococci with hemin or hemoglobin. Uptake of 55Fe bound to TF, LF, dicitrate complexes, aerobactin, or nitrilotriacetate was reduced to 0 to 4% of the wild-type level. FAM11 did not produce an iron-repressible outer membrane protein (FeRP) of 70 kilodaltons (kDa) found in membranes of iron-stressed M986-NCV-1. Western blot (immunoblot) analysis using rabbit antiserum against this protein revealed that at least 17 of 18 meningococcal and 10 of 14 gonococcal strains produced an FeRP of ca. 70 kDa. The 70-kDa FeRP was shown to be surface exposed by radioimmunoprecipitation with human immune sera. These data suggest that the 70-kDa FeRP is somehow involved in Fe uptake from TF and LF. However, we were unable to transform the iron-uptake phenotype from FAM11 into wild-type meningococci to confirm this. Revertants of FAM11 that grew with TF and LF did not regain the ability to make the 70-kDa FeRP but also did not completely regain the Fe-uptake phenotype of M986-NCV-1.
Decay Rate of Iterated Integrals of Branched Rough Paths
Creators: name: Boedihardjo, Horatio
Publisher: name: arXiv
Year: 2015
Subjects: subject: Probability (math.PR)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics

description: Iterated integrals of paths arise frequently in the study of the Taylor's expansion for controlled differential equations. We will prove a factorial decay estimate, conjectured by M. Gubinelli, for the iterated integrals of non-geometric rough paths. We will explain, with a counter example, why the conventional approach of using the neoclassical inequality fails. Our proof involves a concavity estimate for sums over rooted trees and a non-trivial extension of T. Lyons' proof in 1994 for the factorial decay of iterated Young's integrals.
description: 26 pages, 2 figures. Accepted version
Iron uptake from lactoferrin and transferrin by Neisseria gonorrhoeae.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1988

description: The major iron (Fe) sources available to Neisseria gonorrhoeae in the human host are probably transferrin (TF) and lactoferrin (LF). Although a number of studies have examined Fe uptake by Neisseria meningitidis, no comparable studies have been done on Fe uptake by the gonococcus from TF and LF. We found that, like meningococci, gonococci removed Fe from TF and LF in an energy-dependent manner; uptake was repressed by Fe and did not proceed by a siderophore-mediated uptake system. Unlike published studies examining meningococcal Fe uptake from TF, our study showed that gonococcal Fe uptake from both TF and LF was highly efficient; uptake saturated at 1 microM protein, and growth with 5% saturated TF and LF occurred at maximal rates when the protein was present in appreciable concentrations. We conclude that the availability of protein-bound Fe probably does not limit growth of N. gonorrhoeae in the human body.
Assessing asthma self-management education among US children with current asthma, Asthma Call-back Survey (ACBS) 2015–2017
Creators: name: Pattath, Priyadarshini
name: Cornwell, Cheryl R.
name: Sircar, Kanta
name: Qin, Xiaoting
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Asthma self-management education (AS-ME) is an effective strategy to help children with asthma achieve better asthma control and outcome. The objective of this study is to assess the association between the prevalence of receiving AS-ME curriculum components and sociodemographic characteristics among children with current asthma. Behavioral Risk Factor Surveillance System, child Asthma Call-back Survey 2015–2017 aggregated data were used. Multivariable logistic regression models were used to assess associations of each AS-ME component question and sociodemographic characteristic, adjusting for sample weighting. Among 3,213 children with current asthma, 52% of children reported ever being given an asthma action plan by a doctor or other healthcare professional. After adjusting for other variables, boys and Non-Hispanic Black children were more likely to report being given an action plan (APR= 1.15[95% CI 1.00–1.32] and APR= 1.28[95% CI 1.07–1.54] respectively). Non-Hispanic Black (APR = 2.15 [95% CI 1.30–3.55]), non-Hispanic, other race (APR = 1.95 [95% CI1.04–3.66]), and Hispanic children (APR = 1.84 [95% CI 1.18–2.89]) were more likely to report taking a course to learn how to manage asthma than non-Hispanic White children. Hispanic children (40.8%) were more likely to report being advised to change home environment compared to non-Hispanic Whites (31.5%) (APR =1.28 [95% CI 1.01–1.63). The prevalence of some elements of asthma-self management education was relatively low and there were differences observed in the prevalence of receiving AS-ME by race/ethnicity, parental education, and income. Targeted implementation of asthma self-management components and interventions may improve asthma control and reduce asthma morbidity.
Additional file 4 of Patterns of change in obesity indices and other cardiometabolic risk factors before the diagnosis of type 2 diabetes: two decades follow-up of the Tehran lipid and glucose study
Creators: name: Koohi, Fatemeh
name: Ahmadi, Nooshin
name: Azizi, Fereidoun
name: Khalili, Davood
name: Valizadeh, Majid
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Additional file 4: FigureS2. Trajectories of fasting plasma glucose (A), 2-h plasma glucose (B), systolic blood pressure (C), and diastolic blood pressure (D)for women 53 years of age at time 0 from 15 years before the diagnosis of type2 diabetes or last examination. Trajectories for blood pressure represent men,not on antihypertensive treatment. Lines are the estimated trajectories, andshadows are 95% CIs.