cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: New experiences and insights of two-year testing with the leafcutter bee Megachile rotundata in a semi-field test design
Creators: name: Fricke, Julian
name: Gimeno Rodrigo, Ignacio
name: Klein, Olaf
name: Knaebe, Silvio
name: Gimeno, Carmen
Publisher: name: Bundesbehörden und Einrichtungen im Geschäftsbereich des Bundesministeriums für Ernährung und Landwirtschaft (BMEL)
Year: 2025
Subjects: subject: non-Apis
subject: Megachile rotundata
subject: Risk Assessment
subject: 630

description: According to the revised Draft EFSA Bee Guidance Document (EFSA 2023), a key area of concern is the potential risk posed to wild pollinator bee species by the application of plant protection prod-ucts (PPPs). This information holds significant importance due to the limited understanding of wild bee species' exposure. Non-Apis bees comprise a wide range of body sizes as well as biological and life history traits which may result in differences in sensitivity and exposure routes in comparison to honey bees. In the EFSA Bee GD (EFSA 2023) it was advised to consider not only honey bees, but also solitary bees in the plant protection product risk assessment. Authorities require such data to conduct thorough risk assessments for non-Apis bees. Consequently, the ICPPR non-Apis working group has developed a study protocol focusing on the solitary red mason bee Osmia bicornis L., along with recommendations for a standardized Tier II test design (Franke et al 2021). Given the distinct exposure pathways and life-history traits between the solitary bee Osmia bicornis and the alfalfa leafcutter bee Megachile rotundata, it is anticipated that the same PPPs may affect these species differently (Sgolastra et al 2019). In addition, a higher sensitivity of Megachile species to selected PPPs due to a lower detoxification ability was estimated (Hayward et al 2019). The primary aim of the two-year tests, conducted in Spain, was the methodological development of a standardised Tier II study semi-field test design based on the recommended protocol for O. bicornis and to include scenarios for other potential routes of exposure for non-Apis bees towards PPPs to account for these data gaps and uncertainties in a regulatory context and to provide further solutions for the reliability of risk assessment for solitary bees.
description: Julius-Kühn-Archiv, vol. 481Hazards of pesticides to bees, 16th International Symposium of the ICP-PR Bee Protection Group, - Proceedings -; 15th - 17th October, 2024; Sevilla (Spain), p. 94
Optimization and modeling for heat reflux extraction of total yield, stevioside and rebaudioside–A from Stevia rebaudiana (Bertoni) leaves
Creators: name: Ameer, Kashif
name: Seong-Woo Bae
name: Yunhee Jo
name: Namhyeok Chung
name: Yaping Gao
name: Joong-Ho Kwon
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: Stevia rebaudiana (Bertoni) leaves consist of stevioside and rebaudioside-A (Reb-A). This research sought to improve extraction of target steviol glycosides from stevia leaf powder using response surface methodology (RSM) and artificial neural networking (ANN) under these independent variables: ethanol concentration, X1 (0–100%), extraction temperature, X2 (55–75°C), and extraction time, X3 (45–75 min). ANN outperformed as potential alternative to RSM in predicting optimum conditions. Maximum responses were obtained at 100 % X1, 55 °C X2, and 60 min X3. Heat reflux extraction proved superior to maceration extraction in terms of higher extraction yields with reduced energy consumption and CO2 emission.
Supplementary material from “Global leaf sulphur stoichiometry and the relationships with nitrogen and phosphorus: phylogeny, growth form and environmental controls”
Creators: name: Zhang, Liangjian
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310303
subject: Ecological physiology

description: Sulphur (S) is an essential bioelement with vital roles in serving regulatory and catalytic functions, and tightly coupled with N and P in plants. However, globally stoichiometric patterns of leaf S and its relationships to leaf N and P are less well studied. We compiled 31,939 records of leaf-based data for 2,600 plant species across 6,652 sites worldwide. All plant species were divided into different phylogenetic taxa and growth forms. Standard major axis analysis was employed to fit the bivariate element relationships. A phylogenetic linear mixed effect model and a multiple regression model were used to partition the variations of bioelements into phylogeny and environments, and then to estimate the importance of environmental variables. Global geometric mean leaf S, N and P concentrations were 1.44, 15.70 and 1.27 mg g-1, with significant differences among plant groups. Leaf S-N-P positively correlated to each other, ignoring plant groups. The scaling exponents of LN-LS, LP-LS and LN-LP were 0.64, 0.76 and 0.79 for all species, but differed among plant groups. Both phylogeny and environments regulated the bioelements. The variability, rather than mean temperature controlled the bioelements. Phylogeny explained more for the concentrations of all the three bioelements than environments, of which S was the one most affected by phylogenetic taxa.
Supplementary Material for: Comprehensive, Individualized, Person-Centered Management of Community-Residing Persons with Moderate-to-Severe Alzheimer Disease: A Randomized Controlled Trial
Creators: name: Reisberg, B.
name: Shao, Y.
name: Golomb, J.
name: Monteiro, I.
name: Torossian, C.
name: Boksay, I.
name: Shulman, M.
name: Heller, S.
name: Zhu, Z.
name: Atif, A.
name: Sidhu, J.
name: Vedvyas, A.
name: Kenowsky, S.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background/Aims: The aim was to examine added benefits of a Comprehensive, Individualized, Person-Centered Management (CI-PCM) program to memantine treatment. Methods: This was a 28-week, clinician-blinded, randomized, controlled, parallel-group study, with a similar study population, similar eligibility criteria, and a similar design to the memantine pivotal trial of Reisberg et al. [N Engl J Med 2003;348:1333-1341]. Twenty eligible community-residing Alzheimer disease (AD) subject-caregiver dyads were randomized to the CI-PCM program (n = 10) or to usual community care (n = 10). Primary outcomes were the New York University Clinician's Interview-Based Impression of Change Plus Caregiver Input (NYU-CIBIC-Plus), assessed by one clinician set, and an activities of daily living inventory, assessed by a separate clinician set at baseline and at weeks 4, 12, and 28. Results: Primary outcomes showed significant benefits of the CI-PCM program at all post-baseline evaluations. Improvement on the NYU-CIBIC-Plus in the management group at 28 weeks was 2.9 points over the comparator group. The memantine 2003 trial showed an improvement of 0.3 points on this global measure in memantine-treated versus placebo-randomized subjects at 28 weeks. Hence, globally, the management program intervention benefits were 967% greater than memantine treatment alone. Conclusion: These results are approximately 10 times those usually observed with both nonpharmacological and pharmacological treatments and indicate substantial benefits with the management program for advanced AD persons.
Additional file 12: of Similarity of the dog and human gut microbiomes in gene content and response to diet
Creators: name: Coelho, Luis
name: Kultima, Jens
name: Costea, Paul
name: Fournier, Coralie
name: Pan, Yuanlong
name: Czarnecki-Maulden, Gail
name: Hayward, Matthew
name: Forslund, Sofia
name: Schmidt, Thomas
name: Descombes, Patrick
name: Jackson, Janet
name: Li, Qinghong
name: Bork, Peer
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Figure S6. Distance boxplots of the samples in the 3 diets using Bray-Curtis divergence on log-normalized data (corresponding to Fig.Â 2c) (PDF 25Â kb)
Robotic approach for rectal cancer
Creators: name: Buchs, Nicolas
Publisher: name: Université de Genève
Year: 2015
Subjects: info:eu-repo/classification/ddc/617
Surgery
Robotics
Rectal cancer
Laparoscopy
Outcomes

description: Although laparoscopic low anterior resection (LAR) remains a challenging procedure, perioperative and oncological data have been shown it to be at least similar (if not better) than open surgery. Robotics has been recently developed to overcome the limitations associated to laparoscopy. Selected comparative studies between robotic and laparoscopic LAR have shown encouraging outcomes in favor of robotics: a reduction in conversion rate, better oncological margins, better functional outcomes, a shorter learning curve, and better ergonomics. However, robotic surgery for LAR has several drawbacks (size of the system, cost, longer operative time, lack of tactile feedback), which might explain why colorectal surgeons remain circumspect; probably awaiting for larger randomized studies and better meta-analyses. The aim of this study is to review the current literature focusing on robotic rectal resection for cancer. In addition, potential future developments are evaluated and analyzed.
Additional file 13: of Similarity of the dog and human gut microbiomes in gene content and response to diet
Creators: name: Coelho, Luis
name: Kultima, Jens
name: Costea, Paul
name: Fournier, Coralie
name: Pan, Yuanlong
name: Czarnecki-Maulden, Gail
name: Hayward, Matthew
name: Forslund, Sofia
name: Schmidt, Thomas
name: Descombes, Patrick
name: Jackson, Janet
name: Li, Qinghong
name: Bork, Peer
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Evolutionary Biology
subject: Mental Health
subject: Virology
subject: Computational Biology

description: Figure S7. (a) left: Principal coordinate analysis using weighted Unifrac distance [37]; right: corresponding distance boxplot (b) left: Principal coordinate analysis using weighted PINA distance [38]; right: corresponding distance boxplot (*p < 0.05; **p < 0.01; ***p < 0.001: Mann-Whitney-Wilcoxon two-tailed test). (PDF 301 kb)
Prognostic value of biochemical response to neoadjuvant androgen deprivation before external beam radiation therapy in localized or locally-advanced prostate cancer
Creators: name: Zilli, Thomas
Publisher: name: Université de Genève
Year: 2015
Subjects: info:eu-repo/classification/ddc/616.0757
Prostate cancer
Radiotherapy
Androgen deprivation.

description: In this systematic review of the literature we explored the prognostic value of the prostate-specific antigen PSA response to the neoadjuvant androgen deprivation therapy (ADT) phase and the rationale to adjust the use of ADT and external beam radiotherapy in patients with unfavorable intermediate- and high-risk prostate cancer based on the biochemical response to the neoadjuvant androgen ablation phase.
Evaluation of new diagnostic imaging tools in emergency radiology
Creators: name: Platon, Alexandra
Publisher: name: Université de Genève
Year: 2014
Subjects: info:eu-repo/classification/ddc/616.0757

description: Emergency radiology has gained a widespread and rapid development as a subspecialty of diagnostic imaging. Imaging of patients in the emergency department has the particularity of addressing various acute pathologies requiring a fast and precise diagnosis in order to provide a prompt and accurate medical or surgical management. Among all imaging methods, CT and sonography examinations became the pillars of imaging in emergency situations; these techniques also constitute the fundamentals of imaging in our emergency radiology unit at the Geneva University Hospital. Therefore, as part of the academic research group in emergency radiology, my projects were centered on the clinical evaluation of new CT and sonography methods, in order to improve and accelerate the management of patients with various acute clinical conditions. These projects reflect the variety of my research interests in emergency imaging; they address the use of contrast-enhanced sonography in abdominal trauma, the role of total-body CT in polytrauma patients, the clinical utilization of low-dose CT abdominal examinations, the set-up of clinico-radiological scores helpful for the clinicians in the management of frequent acute abdominal pathologies, such as diverticulitis and small-bowel obstruction and the development of new informatics tools for the characterization of interstitial lung diseases. The current habilitation thesis is structured in three parts. The introduction describes the advent and the gradual development of emergency radiology, with enhancement on my research projects leading to implementation of new sonographic and computed-tomography techniques in our emergency radiology section. The second part consists of short presentations of the most representative publications of my research activity, further detailed in the appendix section. The final part provides an overview of my current research projects, focused on clinical evaluation of new CT technologies, namely dual-energy techniques and iterative image reconstructions protocols.
Additional file 14: of Similarity of the dog and human gut microbiomes in gene content and response to diet
Creators: name: Coelho, Luis
name: Kultima, Jens
name: Costea, Paul
name: Fournier, Coralie
name: Pan, Yuanlong
name: Czarnecki-Maulden, Gail
name: Hayward, Matthew
name: Forslund, Sofia
name: Schmidt, Thomas
name: Descombes, Patrick
name: Jackson, Janet
name: Li, Qinghong
name: Bork, Peer
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Developmental Biology

description: Figure S8. (a) Firmicutes:Bacteroidetes ratio at the end of the Base feeding period (no significant difference) (b) Firmicutes and Bacteroidetes relative abundances (c) Firmicutes:Bacteroidetes ratio (*p < 0.05; **p < 0.01; ***p < 0.001: Mann-Whitney-Wilcoxon two-tailed test). (PDF 350 kb)
Shared permutation for syndrome decoding: new zero-knowledge protocol and code-based signature
Creators: name: Feneuil, Thibauld
name: Joux, Antoine
name: Rivain, Matthieu
Publisher: name: CISPA
Year: 2024

description: The threat of a coming quantum computer motivates the research for new zero-knowledge proof techniques for (or based on) post-quantum cryptographic problems. One of the few directions is code-based cryptography for which the strongest problem is the syndrome decoding (SD) of random linear codes. This problem is known to be NP-hard and the cryptanalysis state of affairs has been stable for many years. A zero-knowledge protocol for this problem was pioneered by Stern in 1993. As a simple public-coin three-round protocol, it can be converted to a post-quantum signature scheme through the famous Fiat-Shamir transform. The main drawback of this protocol is its high soundness error of 2/3, meaning that it should be repeated \(\approx 1.7 \lambda \) times to reach a \(\lambda \)-bit security. In this paper, we improve this three-decade-old state of affairs by introducing a new zero-knowledge proof for the syndrome decoding problem on random linear codes. Our protocol achieves a soundness error of 1/n for an arbitrary n in complexity \(\mathcal {O}(n)\). Our construction requires the verifier to trust some of the variables sent by the prover which can be ensured through a cut-and-choose approach. We provide an optimized version of our zero-knowledge protocol which achieves arbitrary soundness through parallel repetitions and merged cut-and-choose phase. While turning this protocol into a signature scheme, we achieve a signature size of 17 KB for a 128-bit security. This represents a significant improvement over previous constructions based on the syndrome decoding problem for random linear codes.
การพัฒนาคุกกี้หน่อกะลา(Alpinia nigraBurrt) ปราศจากกลูเตน
Creators: name: นรินทร์ เจริญพันธ์, จิราณีย์ พันมูล, สุธิษา เละเซ็น
Publisher: name: กองบริหารการวิจัย
Year: 2563
Subjects: หน่อกะลา
คุกกี้
อาหารชนิดปราศจากกลูเตน

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 28, 4, 642-655
In situ quantification of diverse titanium dioxide nanoparticles unveils selective endoplasmic reticulum stress-dependent toxicity
Creators: name: Simon, Marina
name: Saez, Gladys
name: Muggiolu, Giovanna
name: Lavenas, Magali
name: Trequesser, Quentin Le
name: Michelet, Claire
name: Devès, Guillaume
name: Barberet, Philippe
name: Chevet, Eric
name: Dupuy, Denis
name: Marie-Hélène Delville
name: Seznec, Hervé
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Although titanium dioxide nanoparticles (TiO2 NPs) have been extensively studied, their possible impact on health due to their specific properties supported by their size and geometry, remains to be fully characterized to support risk assessment. To further document NPs biological effects, we investigated the impact of TiO2 NPs morphology on biological outcomes. To this end, TiO2 NPs were synthesized as nanoneedles (NNs), titanate scrolled nanosheets (TNs), gel-sol-based isotropic nanoparticles (INPs) and tested for perturbation of cellular homeostasis (cellular ion content, cell proliferation, stress pathways) in three cell types and compared to the P25. We showed that TiO2 NPs were internalized at various degrees and their toxicity depended on both titanium content and NPs shape, which impacted on intracellular calcium homeostasis thereby leading to endoplasmic reticulum stress. Finally, we showed that a minimal intracellular content of TiO2 NPs was mandatory to induce toxicity enlightening once more the crucial notion of internalized dose threshold beside the well-recognized dose of exposure.
Additional file 10: of Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities
Creators: name: Garrett, Matthew
name: Sperry, Jantzen
name: Braas, Daniel
name: Yan, Weihong
name: Le, Thuc
name: Mottahedeh, Jack
name: Ludwig, Kirsten
name: Eskin, Ascia
name: Qin, Yue
name: Levy, Rachelle
name: Breunig, Joshua
name: Pajonk, Frank
name: Graeber, Thomas
name: Radu, Caius
name: Christofk, Heather
name: Prins, Robert
name: Lai, Albert
name: Liau, Linda
name: Coppola, Giovanni
name: Kornblum, Harley
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Effects of pharmacologic inhibition of the IDH1 mutant enzyme on TCA cycle intermediates. Cells were analyzed as described in Supporting Figure S5. Left: Metabolites with significantly different percent glucose labeling of metabolites in the endogenous IDH1 mutant line 213 treated with c227 inhibitor or control (pâ <â 0.05). Right: Percent labeling from endogenous IDH1 mutant and IDH wildtype groups for metabolites that were not significantly different. (PDF 206Â kb)
Additional file 15: of Similarity of the dog and human gut microbiomes in gene content and response to diet
Creators: name: Coelho, Luis
name: Kultima, Jens
name: Costea, Paul
name: Fournier, Coralie
name: Pan, Yuanlong
name: Czarnecki-Maulden, Gail
name: Hayward, Matthew
name: Forslund, Sofia
name: Schmidt, Thomas
name: Descombes, Patrick
name: Jackson, Janet
name: Li, Qinghong
name: Bork, Peer
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Figure S9. (a) Bacteroides and Prevotella relative abundances as a function of the diet. (b) ratios between the two genera (*p < 0.05; **p < 0.01; ***p < 0.001: Mann-Whitney-Wilcoxon two-tailed test). (PDF 259 kb)
Functional results of hemi- and total shoulder arthroplasty according to diagnosis and patient age at surgery
Creators: name: Sowa, Boris
name: Thierjung, Heidi
name: Bülhoff, Matthias
name: Loew, Markus
name: Zeifang, Felix
name: Bruckner, Thomas
name: Raiss, Patric
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Background and purpose — There is a lack of information on any associations between the functional outcome and age and diagnosis in patients who have undergone shoulder arthroplasty. We therefore evaluated the functional outcome in “young” and “old” patients treated with either hemiarthroplasty (HA) or total shoulder arthroplasty (TSA) with diverse diagnoses. Patients and methods — The functional results of 496 primary shoulder arthroplasties were analyzed using the Constant score (age- and sex-adjusted) and subjective satisfaction. Patients ≤55 years of age at surgery were defined as “young. Diagnoses were primary osteoarthritis (n = 339), posttraumatic osteoarthritis (n = 78), cuff tear arthropathy (n = 36), avascular necrosis (n = 30), and rheumatoid arthritis (n = 13). Mean length of follow-up was 4 (2–14) years. Results — 70% of the TSA patients were very satisfied with the postoperative result, as compared to 39% after HA. The Constant score and patient satisfaction were similar in the “young” and “old” groups. Pain relief was better in the “old” group. The mean improvement in the Constant score after cuff tear arthropathy (22 points) was inferior to that for primary osteoarthritis (36 points), avascular necrosis (34 points), and rheumatoid arthritis (37 points). Inferior mean Constant scores were also seen for posttraumatic osteoarthritis (29 points) compared to primary osteoarthritis (36 points). 63% of patients with primary osteoarthritis were very satisfied, as compared to only 36% of the patients with posttraumatic osteoarthritis. Interpretation — Shoulder arthroplasty is successful in the medium term for different glenohumeral diseases, irrespective of patient age at surgery. However, the appropriate treatment method for cuff tear and posttraumatic conditions of the shoulder remains to be found, particularly in young patients.
Additional file 16: of Similarity of the dog and human gut microbiomes in gene content and response to diet
Creators: name: Coelho, Luis
name: Kultima, Jens
name: Costea, Paul
name: Fournier, Coralie
name: Pan, Yuanlong
name: Czarnecki-Maulden, Gail
name: Hayward, Matthew
name: Forslund, Sofia
name: Schmidt, Thomas
name: Descombes, Patrick
name: Jackson, Janet
name: Li, Qinghong
name: Bork, Peer
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Figure S10. Prevalence change split by experimental cohorts (cf. Fig.Â 3a). (PDF 42Â kb)
Prominence perception is dependent on phonology, semantics, and awareness of discourse
Creators: name: Turnbull, Rory
name: Royer, Adam J.
name: Ito, Kiwako
name: Speer, Shari R.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The perception of prosodic prominence is thought to be influenced by multiple competing factors. Three experiments tested the effects of phonological salience, discourse context and listener’s knowledge about the discourse on prosodic prominence judgements, using short adjective–noun phrases extracted from a corpus of spontaneous speech. These phrases had either a prominent L + H* 0 or a less prominent H* !H* pitch accent contour. The phrases were presented in a discourse context which either supported or did not support a contrastive interpretation of the adjective. Effects of the contrastive context to increase the perception of prominence only emerged for the phrases with the phonologically prominent L + H* 0 pitch accent sequence. Additionally, the magnitude of the contrast effect was correlated with the listener’s awareness of the discourse context, suggesting an ample interplay between linguistic context, pragmatic context, and phonology in prominence perception.
Additional file 1: of Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities
Creators: name: Garrett, Matthew
name: Sperry, Jantzen
name: Braas, Daniel
name: Yan, Weihong
name: Le, Thuc
name: Mottahedeh, Jack
name: Ludwig, Kirsten
name: Eskin, Ascia
name: Qin, Yue
name: Levy, Rachelle
name: Breunig, Joshua
name: Pajonk, Frank
name: Graeber, Thomas
name: Radu, Caius
name: Christofk, Heather
name: Prins, Robert
name: Lai, Albert
name: Liau, Linda
name: Coppola, Giovanni
name: Kornblum, Harley
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Patient-derived gliomasphere culture characteristics. Relevant patient information and clinical characteristics for the primary, patient-derived gliomasphere cultures used in this study. Summary of selected copy-number alterations and mutations are also shown. (PDF 42Â kb)
Additional file 2: of Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities
Creators: name: Garrett, Matthew
name: Sperry, Jantzen
name: Braas, Daniel
name: Yan, Weihong
name: Le, Thuc
name: Mottahedeh, Jack
name: Ludwig, Kirsten
name: Eskin, Ascia
name: Qin, Yue
name: Levy, Rachelle
name: Breunig, Joshua
name: Pajonk, Frank
name: Graeber, Thomas
name: Radu, Caius
name: Christofk, Heather
name: Prins, Robert
name: Lai, Albert
name: Liau, Linda
name: Coppola, Giovanni
name: Kornblum, Harley
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: 2-HG inhibition with c227 moderately increases DNA damage following radiation but does not reverse the IDH1 mutant phenotype to an IDH wildtype phenotype. A-B. Assessment of DNA damage and repair by comet analysis following irradiation (10 Gy). HK252 was treated for 48 h with 5 μM c227 or control prior to comet analysis and compared to the IDH WT line HK157. A. Similar analysis of tail moment length as conducted in Fig. 4. B. Graph showing the percent of cells with comets as explained in Fig. 4. All error bars represent ± SEM. (PDF 46 kb)
Living kidney transplantation: beyond immunological barriers
Creators: name: Hadaya, Karine
Publisher: name: Université de Genève
Year: 2014
Subjects: info:eu-repo/classification/ddc/616
Living kidney donation
ABO incompatibility
Donor specific antibodies
Kidney paired donation
Altruistic donors.

description: Although criteria for living kidney donations have greatly evolved in recent years with acceptance of related and unrelated donors, an immunological incompatibility, between a living donor and his intended recipient, could impede up to 40% of such procedures. To avoid refusal of willing and healthy living donors, different strategies have emerged to overcome immunological incompatibilities. ABO incompatible kidney transplantation can now be achieved with identical outcomes to compatible/identical kidney transplantation and kidney paired donation is the safest way for HLA-incompatible patients to undergo kidney transplantation. Implemented with success in many countries either as national or multiple regional independent programs, kidney paired donation could include simple exchanges between any number of incompatible pairs, incorporate compatible pairs and non-directed donors to start a chain of compatible transplantations, lead to acceptance of ABO-incompatible matching, and integrate desensitizing protocols. Incorporating all these variations, kidney paired donation has been able to facilitate kidney transplantation in up to 49% of registered patients from incompatible pairs.
Additional file 3: of Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities
Creators: name: Garrett, Matthew
name: Sperry, Jantzen
name: Braas, Daniel
name: Yan, Weihong
name: Le, Thuc
name: Mottahedeh, Jack
name: Ludwig, Kirsten
name: Eskin, Ascia
name: Qin, Yue
name: Levy, Rachelle
name: Breunig, Joshua
name: Pajonk, Frank
name: Graeber, Thomas
name: Radu, Caius
name: Christofk, Heather
name: Prins, Robert
name: Lai, Albert
name: Liau, Linda
name: Coppola, Giovanni
name: Kornblum, Harley
Publisher: name: figshare
Year: 2018
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: IDH1 mutant cells are better able to proliferate following radiation than IDH wildtype cells. A. Growth curve following radiation (0 and 10Â Gy) shows average fold increases in cell number between IDH wildtype and IDH1 mutant groups over three passages. Each group consists of three IDH1 mutant and three IDH wildtype cultures respectively. Growth curves were generated from individual cell counts at each time point. B. Identical growth curve as shown in (A), however, the non-irradiated groups have been removed for better visual comparison between irradiated IDH mutant and wildtype groups. Error bars represent Âą STDEV. (PDF 51Â kb)
ผลของเนื้อเยื่อเริ่มต้นและสารควบคุมการเจริญเติบโต ต่อการเพาะเลี้ยงแคลลัสของเจตมูลเพลิงแดงเพื่อผลิตสารพลัมบาจิน
Creators: name: เพชรรัตน์ จันทรทิณ, ศศิวิมล จันทร์สุเทพ, สนธิชัย จันทร์เปรม, เสริมศิริ จันทร์เปรม
Publisher: name: กองบริหารการวิจัย
Year: 2563
Subjects: เจตมูลเพลิงแดง
แคลลัส
สารพลัมบาจิน
สารควบคุมการเจริญเติบโตของพืช

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 28, 4, 656-664
Additional file 4: of Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities
Creators: name: Garrett, Matthew
name: Sperry, Jantzen
name: Braas, Daniel
name: Yan, Weihong
name: Le, Thuc
name: Mottahedeh, Jack
name: Ludwig, Kirsten
name: Eskin, Ascia
name: Qin, Yue
name: Levy, Rachelle
name: Breunig, Joshua
name: Pajonk, Frank
name: Graeber, Thomas
name: Radu, Caius
name: Christofk, Heather
name: Prins, Robert
name: Lai, Albert
name: Liau, Linda
name: Coppola, Giovanni
name: Kornblum, Harley
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: Virology

description: KEGG gene set enrichment analysis of IDH1 mutant and wildtype gliomaspheres. Thirty-five modules were enriched in IDH wildtypes compared to four modules in IDH1 mutants. (PDF 79Â kb)
Clinical Aspects of Velopharyngeal Insufficiency
Creators: name: Leuchter, Igor
Publisher: name: Université de Genève
Year: 2015
Subjects: info:eu-repo/classification/ddc/616.8
Velopharyngeal insufficiency
Evaluation
Nasometry

description: Velopharyngeal insufficiency (VPI) is due to an incomplete closure of the valve separating the oral and the nasal cavities and manifests as a nasalized voice, articulation problems, and sometimes swallowing disorders. The etiologies are anatomic, neurogenic or functional. The evaluation of VPI remains challenging and is the key to the management. This work provides an overview of current knowledge in velopharyngeal anatomy and physiology, VPI evaluation techniques and therapeutic modalities. A comprehensive review of literature is presented, with a focus on the controversial innervation of the velopharyngeal muscles and on the perceptual and instrumental evaluation of resonance disorders in VPI. Lastly, an attempt is made to identify the “grey” areas still existing in the field of VPI evaluation and treatment, and to define research perspectives.
Additional file 5: of Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities
Creators: name: Garrett, Matthew
name: Sperry, Jantzen
name: Braas, Daniel
name: Yan, Weihong
name: Le, Thuc
name: Mottahedeh, Jack
name: Ludwig, Kirsten
name: Eskin, Ascia
name: Qin, Yue
name: Levy, Rachelle
name: Breunig, Joshua
name: Pajonk, Frank
name: Graeber, Thomas
name: Radu, Caius
name: Christofk, Heather
name: Prins, Robert
name: Lai, Albert
name: Liau, Linda
name: Coppola, Giovanni
name: Kornblum, Harley
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: IDH wildtype cells show faster growth rate compared to IDH1 mutant cells. Six IDH wildtype and five IDH1 mutant gliomasphere cultures were assessed for proliferation rate by flow cytometry using carboxyfluorescein succinimidyl ester (CFSE). (pâ <â 0.05). (PDF 19Â kb)
Software
Creators: name: Grimmer, Hilary
name: Laukkonen, Ruben Eero
name: Tangen, Jason M
name: Von Hippel, Bill
Publisher: name: OSF Registries
Year: 2019

description: This component contains the LiveCode source file (version 9.5.0) for presenting the sequences and materials to participants and collecting their responses. LiveCode’s Community Edition, is a free open source object-oriented, cross-platform, natural language rapid development environment that can be used for programming local (LiveCode) and web-based (HTML5) experiments. LiveCode is based on the Transcript programming language (a high-level xTalk scripting language like HyperCard’s HyperTalk), and is a great stepping stone to learning Javascript and Python. It is fit for developing experiments that require fine-grained control, complex sequencing, and heavy back-end processing. You can download LiveCode for PC, Linux or Mac at: https://downloads.livecode.com/livecode. You can run this experiment on your own computer by installing the appropriate version of LiveCode Community, and downloading the zip file.
Additional file 6: of Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities
Creators: name: Garrett, Matthew
name: Sperry, Jantzen
name: Braas, Daniel
name: Yan, Weihong
name: Le, Thuc
name: Mottahedeh, Jack
name: Ludwig, Kirsten
name: Eskin, Ascia
name: Qin, Yue
name: Levy, Rachelle
name: Breunig, Joshua
name: Pajonk, Frank
name: Graeber, Thomas
name: Radu, Caius
name: Christofk, Heather
name: Prins, Robert
name: Lai, Albert
name: Liau, Linda
name: Coppola, Giovanni
name: Kornblum, Harley
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Glucose labeling of metabolites. Glucose fractional contribution was computed for all 159 metabolites. Metabolites that were significantly different between groups (uncorrected t test pâ <â 0.05) are shown here. (PDF 137Â kb)
Detail description of applied rock magnetic and palaeomagnetic procedures. Using palaeomagnetic and isotopic data to investigate late to post-Caledonian tectonothermal processes within the Western Terrane of Svalbard
Creators: name: Michalski, Krzysztof
name: Manby, Geoffrey
name: Nejbert, Krzysztof
name: Domańska-Siuda, Justyna
name: Burzyński, Mariusz
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary data 2 - Detail description of applied rock magnetic and palaeomagnetic procedures
Field characteristics of metabasic sites. Using palaeomagnetic and isotopic data to investigate late to post-Caledonian tectonothermal processes within the Western Terrane of Svalbard
Creators: name: Michalski, Krzysztof
name: Manby, Geoffrey
name: Nejbert, Krzysztof
name: Domańska-Siuda, Justyna
name: Burzyński, Mariusz
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary data 1 - Field characteristics of metabasic sites
Microscopic images of investigated geochronological samples. Using palaeomagnetic and isotopic data to investigate late to post-Caledonian tectonothermal processes within the Western Terrane of Svalbard
Creators: name: Michalski, Krzysztof
name: Manby, Geoffrey
name: Nejbert, Krzysztof
name: Domańska-Siuda, Justyna
name: Burzyński, Mariusz
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary data 3 - Microscopic images of investigated geochronological samples
Anisotropy of magnetic susceptibility. Using palaeomagnetic and isotopic data to investigate late to post-Caledonian tectonothermal processes within the Western Terrane of Svalbard
Creators: name: Michalski, Krzysztof
name: Manby, Geoffrey
name: Nejbert, Krzysztof
name: Domańska-Siuda, Justyna
name: Burzyński, Mariusz
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary data 6 - Anisotropy of magnetic susceptibility
Neuroanatomical and Neuropsychological Features of Elderly Euthymic Patients With Bipolar Disorder or Early-Onset Depression
Creators: name: Delaloye, Christophe
Publisher: name: Université de Genève
Year: 2013
Subjects: info:eu-repo/classification/ddc/616.89
Aging
Elderly
Bipolar disorder
Unipolar depression
Cognition
Structural imaging

description: We explored whether chronic mood disorder has a long-term «toxic effect» on cognition and brain structures. We performed a 2-year longitudinal study of four groups of elderly individuals: euthymic patients suffering from bipolar disorder (BD), euthymic patients presenting an early (EOD) or a late-onset (LOD) of depression and healthy elderly. Regarding BD, patients displayed significantly lower performances in processing speed and episodic memory but not in working memory and executive functions compared to controls. However, BD patients did not differ from controls in the mean trajectory of cognitive changes during the two years follow-up. In the same line, longitudinal grey matter and white matter changes did not differ between BD patients and controls. Our results suggest that BD does not have a significant adverse impact. Regarding EOD, results revealed that cognitive performances as well as brain volumes were preserved in EOD patients both at baseline and at follow-up. LOD patients showed decreased performances limited to episodic memory tasks. Besides, MRI analyses found that they had significantly greater periventricular hyperintensities than controls. Our results support the distinction between the aetiological mechanisms implicated in the pathogenesis of LOD and EOD.
Additional file 7: of Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities
Creators: name: Garrett, Matthew
name: Sperry, Jantzen
name: Braas, Daniel
name: Yan, Weihong
name: Le, Thuc
name: Mottahedeh, Jack
name: Ludwig, Kirsten
name: Eskin, Ascia
name: Qin, Yue
name: Levy, Rachelle
name: Breunig, Joshua
name: Pajonk, Frank
name: Graeber, Thomas
name: Radu, Caius
name: Christofk, Heather
name: Prins, Robert
name: Lai, Albert
name: Liau, Linda
name: Coppola, Giovanni
name: Kornblum, Harley
Publisher: name: figshare
Year: 2018
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Virology

description: Radiation leads to low levels of TUNEL staining in gliomaspheres. Representative images and quantification of cells stained for TUNEL positivity 4Â days after exposure to increasing doses of radiation. There is no significant difference between groups. Error bars represent Âą SEM. (PDF 2212Â kb)
Fine-needle aspiration biopsy of head and neck masses: ongoing challenges and recent advances
Creators: name: Pusztaszeri, Marc
Publisher: name: Université de Genève
Year: 2015
Subjects: info:eu-repo/classification/ddc/616.07
Fine-needle aspiration
Cytology
Thyroid
Head and neck
Salivary glands
Ancillary studies

description: Fine-needle aspiration biopsy (FNAB) is currently the first line investigation for the diagnosis and triage of head and neck masses. Cytomorphological evaluation of FNAB specimens allows a diagnosis in many cases. However, there are many challenging diagnostic areas in the head and neck including thyroid neoplasia, salivary gland neoplasia, and lymph nodes. Important advances in FNAB diagnosis have been made over the last decades, especially with the routine use of several ancillary techniques and markers on FNAB specimens that have allowed optimizing the cytomorphological diagnosis, and have reshaped the practice of cytopathology. In this thesis, we discuss the major role and limitations of FNAB for the diagnosis of thyroid nodules, cervical lymphadenopathies and salivary gland lesions. We cover some of the current challenges in these areas, selected diagnostic pitfalls, and recent advances including ancillary techniques such as immunocytochemistry and molecular analyses that can be applied on FNAB samples.
The larval biology of Culicoides ornatus Taylor in mangroves near Darwin, Northern Territory
Creators: name: Shivas, Martin
Publisher: name: Charles Darwin University
Year: 1999

description: Culicoides ornatus is the main pest species of biting midge in coastal northern Australia. As the control of biting midges is usually not practical after they have dispersed from their larval habitat, and as little was known about the larval biology of C. ornatus, this study was undertaken to identify and characterise the location of larval habitats within mangroves near Darwin. Emergence trapping was used to identify larval habitats. Three types of larval habitat were found, each associated with a particular mangrove vegetation zone. The highest densities of emerging midges were recorded at the edge of the vegetation line on creekbanks of the upper reaches of small tidal creeks (around Mean High Water Neap), while low to moderate emergence was found in both the transitional zone of Bruguiera and Ceriops at the landward edge of the creekbank forest (just below Mean High Water Spring), and in the Sonneratia zone at the seaward edge of mangrove lined foreshores (between Mean Low Water Neap and Mean Sea Level). Creekbanks were a dry season only habitat, the transitional zone was a wet season only habitat, and the seasonal pattern of emergence was not determined in the Sonneratia zone, sampling only being undertaken in the late dry season. Peak emergence within each fortnightly tidal cycle occurred around the day of the neap tide, with a variation of three to four days through the year. Emergence occurred later at higher tidal elevations, with a four day difference between the time of emergence in the Sonneratia zone and at creekbank sites. Emergence was also greater on pre-full moon cycles than on pre-new moon cycles, after allowing for seasonal changes in numbers. Synchronised emergence appeared to be the result of the synchronisation of pupation. Field data indicated that there was a tidal cue for pupation, that it coincided with exposure of the habitat by an ebb tide, and that there was a circadian basis to its perception by larvae. Emerging females were autogenous, moving out of the mangroves and into the adjacent hinterland in search of blood meals immediately after their first oviposition. The extensive distribution of larval habitats within the mangroves near Darwin indicated that, using current technology, control methods aimed at the larval habitat such as insecticidal spraying or habitat modification, are unlikely to be either effective or environmentally acceptable. Consequently, control must continue to rely on methods such as the use of buffer zones between mangroves and residential communities, and personal protection and avoidance.
Vehicular Imprinting Effect
Creators: name: Pralhad Adhikari
Publisher: name: Zenodo
Year: 2020

description: [I propose a new concept in road psychology] Suppose we are driving a vehicle following another one. When we cannot overtake a vehicle in front of us, especially a larger one, in roads such as serpentine type, we simply follow the vehicle in front of us as if we are hypnotized. This effect of following the vehicle in front of us or fixing our attention in the lead vehicle is called Vehicular Imprinting Effect (VIE).
การขยายพันธุ์ด้วยการเพาะเลี้ยงเนื้อเยื่อของกระเทียมน้้า (Isoetes coromandelinaL.f.): ไลโคไฟต์หายากของประเทศไทย
Creators: name: ศรัณย์พร ล่องชูผล, อารยา อาจเจริญ เทียนหอม, ทัศไนย จารุวัฒนพันธ์
Publisher: name: กองบริหารการวิจัย
Year: 2563
Subjects: พืชคล้ายเฟิร์น
กระเทียมน้ำ
สภาพปลอดเชือ

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 28, 4, 665-674
การใช้เส้นใยและผงไทเทเนียมไดออกไซด์กําจัดสปอร์ของ Bacillus subtilis ในน้ํา
Creators: name: ชัญฐิศา ประพันธ์พจน์, ภารดี ช่วยบำรุง, สิทธิสุนทร สุโพธิณะ
Publisher: name: กองบริหารการวิจัย
Year: 2563
Subjects: ปฏิกิริยาโฟโตคะตะไลสิส
อนาเทส
รูไทล์
เส้นใยนาโนไทเทเนียมไดออกไซด์

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 28, 4, 675-687
ประสิทธิภาพของสารสกัดโมโนกลีเซอร์ไรด์จากน้ํามันมะพร้าวกลั่นบริสุทธิ์ในการยับยั้งการเจริญของราแคนดิดา อัลบิแคนส์ที่ดื้อต่อยาฟลูโคนาโซลในห้องปฏิบัติการ
Creators: name: ธนาศักดิ์ รักษ์มณี, นันทวรรณ กระจ่างตา, ยุทธพงศ์ โลไธสงค์, กษิตินษ์ นันทวิสุทธิ์, บุรฉัตร เรืองดิษฐ์, วรดา สโมสรสุข
Publisher: name: กองบริหารการวิจัย
Year: 2563
Subjects: แคนดิดา อัลบิแคนส์
สารสกัดโมโนกลีเซอไรด์
น้ํามันมะพร้าวกลั่นบริสุทธิ์
ยาฟลูโคนาโซล

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 28, 4, 688-704