cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Differential roles of extracellular histidine residues of GPR68 for proton-sensing and allosteric modulation by divalent metal ions
Creators: name: Kenakin T.P
name: Huang X.-P
name: Shoichet B.K
name: Gu S
name: Roth B.L
Publisher: name: American Chemical Society
Year: 2020

description: GPR68, an orphan G-protein coupled receptor, senses protons, couples to multiple G-proteins, and is also activated or inhibited by divalent metal ions. It has seven extracellular histidine residues, although it is not clear how these histidine residues play a role in both proton-sensing and metal ion modulation. Here we demonstrate that divalent metal ions are allosteric modulators that can activate or inhibit proton activity in a concentration- and pH-dependent manner. We then show that single histidine mutants have differential and varying degrees of effects on proton-sensing and metal ion modulation. Some histidine residues play dual roles in proton-sensing and metal ion modulation, while others are important in one or the other but not both. Two extracellular disulfide bonds are predicted to constrain histidine residues to be spatially close to each other. Combining histidine mutations leads to reduced proton activity and resistance to metal ion modulation, while breaking the less conserved disulfide bond results in a more severe reduction in proton-sensing over metal modulation. The small-molecule positive allosteric modulators (PAMs) ogerin and lorazepam are not affected by these mutations and remain active at mutants with severely reduced proton activity or are resistant to metal ion modulation. These results suggest GPR68 possesses two independent allosteric modulation systems, one through interaction with divalent metal ions at the extracellular surface and another through small-molecule PAMs in the transmembrane domains. A new GPR68 model is developed to accommodate the findings which could serve as a template for further studies and ligand discovery by virtual ligand docking.
Ocnerodrilidae
Creators: name: Ferreira, Talita
name: Niva, Cintia C.
name: Dudas, Rafaela
name: Roani, Rodrigo
name: Durães, Natália
name: Marchão, Robélio Leandro
name: James, Samuel Wooster
name: Bartz, Marie L. C.
name: Brown, George G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Clitellata
Haplotaxida
Ocnerodrilidae

description: Ocnerodrilidae (juveniles)   BRGO0038, 2 individuals, in a pre-planting agroecological crop area, Silvânia-GO (S16°34'3.52" W48°35'51.89"), 29 November 2016, C. C. Niva, C. T. de T. Machado, A. dos S. Lima, colls. BRDF0108, 1 juvenile in pasture with Urochloa brizantha cv Piat„, Embrapa Cerrados, Planaltina-DF (S15º38’54.25” W47º44’45.55”), February 2019, C. Niva, M. Bartz, G. Brown, A. Santos, L. Maia, G. Dur„es, T. Ferreira, N. Satiro, colls. BRDF0387, 1 individual, in soil beside a streamlet bordering the Cerrad„o, Planaltina-DF (S15°36'23.77" W47°42'31.20"), 4 March 2020, C. C. Niva, W. de M. Araújo, A. E. C. B. Guedes, N. Dur„es.
description: Published as part of Ferreira, Talita, Niva, Cintia C., Dudas, Rafaela, Roani, Rodrigo, Durães, Natália, Marchão, Robélio Leandro, James, Samuel Wooster, Bartz, Marie L. C. & Brown, George G., 2023, Earthworm species in different land use systems in the state of Goiás and the Federal District of Brazil, pp. 283-303 in Zootaxa 5255 (1) on page 295, DOI: 10.11646/zootaxa.5255.1.24, http://zenodo.org/record/7744899
Additional file 1 of Single-drug versus combination antimicrobial therapy in critically ill patients with hospital-acquired pneumonia and ventilator-associated pneumonia due to Gram-negative pathogens: a multicenter retrospective cohort study
Creators: name: Barbier, François
name: Dupuis, Claire
name: Buetti, Niccolò
name: Schwebel, Carole
name: Azoulay, Élie
name: Argaud, Laurent
name: Cohen, Yves
name: Hong Tuan Ha, Vivien
name: Gainnier, Marc
name: Siami, Shidasp
name: Forel, Jean-Marie
name: Adrie, Christophe
name: de Montmollin, Étienne
name: Reignier, Jean
name: Ruckly, Stéphane
name: Zahar, Jean-Ralph
name: Timsit, Jean-François
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 1. Supplementary tables and figures.
title: A Spatial Analysis of Boko Haram and Al-Shabaab References in Social Media in Sub-Saharan Africa
Creators: name: Rodriguez, Richard Michael
Publisher: name: George Mason University
Year: 2014
Subjects: subject: Social media
subject: Boko Haram
subject: Al-Shabaab
subject: Geospatial

description: This thesis describes the role that social media can play in showing how terrorist organization can impact people’s conversation via Twitter. The two groups that this thesis focusses on are Boko Haram and Al-Shabaab. We present a new approach of how we can look into how terrorist organization can be analyzed and see what kind of impacts they may have over different cultures. The process used in researching and writing this thesis, is we conducted literature search of the social media phenomenon and what social media can provide. We look to build on research by using the social media phenomenon to find what types of impacts terrorist organizations may have over cultures along with seeing how a terrorist event can have impact over people on social media. This thesis hopes to expand on previous research on the academic uses for social media, as well as add to the expanding role that social media can be used for intelligence purposes.
Direct Observation of Fast Carriers Transport along Out-of-Plane Direction in a Dion-Jacobson Layered Perovskite
Creators: name: Shi Z
name: Ni Z
name: Huang J
Publisher: name: American Chemical Society
Year: 2022

description: Layered perovskites have been broadly applied in perovskite solar cells and light-emitting diodes to enhance device stability, but the poor carrier transport property along the out-of-plane direction for all known Ruddlesden-Popper (RP) layered perovskites imposes constraints to their application. Herein, using transient photoluminescence mapping, we visualized that the transport of carriers or excitons along the out-of-plane direction is comparable to along the in-plane direction in a Dion-Jacobson (DJ) layered perovskite, which has the reduced ligand length and stronger I···I electronic interaction between inorganic layers.
What QCD sum rules tell about the rho meson
Creators: name: Leupold, Stefan
name: Peters, Wolfram
name: Mosel, Ulrich
Publisher: name: arXiv
Year: 1997
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Using a simple parametrization of Breit-Wigner type for the hadronic side of the QCD sum rule for $ρ$ mesons in vacuum as well as in a nuclear medium we explore the range of values for the mass and the width of the $ρ$ meson which are compatible with the operator product expansion.
description: 15 pages, Revtex, 2 figures included
Quantum oscillations in strongly correlated topological Kondo insulators
Creators: name: Peters, Robert
name: Yoshida, Tsuneya
name: Kawakami, Norio
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The observation of quantum oscillations in topological Kondo insulators SmB6 and YbB12 is a recent puzzling experimental discovery. Quantum oscillations observed in the resistivity and the magnetization are usually explained by the existence of the Fermi surface. However, Kondo insulators do not have a Fermi surface and thus should not show quantum oscillations. By performing dynamical mean-field calculations for topologically nontrivial Kondo insulators in a magnetic field, we analyze the effect of correlations on the emergence of quantum oscillations in narrow-gap topological Kondo insulators and demonstrate that the interplay between correlations and nonlocal hybridization, ubiquitously occurring in topological Kondo insulators, can lead to observable quantum oscillations without the necessity of a Fermi surface. Particularly, we show that correlations make it easier to observe quantum oscillations in the magnetization and the resistivity of the bulk material. The fundamental mechanism for these quantum oscillations is a combination of correlation effects and Landau levels coming very close to the Fermi energy. We furthermore demonstrate that quantum oscillations in a three-dimensional system can be understood by analyzing the physics on the two-dimensional planes in the momentum space for which the hybridization in direction of the magnetic field vanishes. We believe that this scenario is relevant to understanding the observation of quantum oscillations in the magnetic torque for SmB6 as well as oscillations in the resistivity and the magnetic torque of YbB12.
description: 13 pages
Gravitational waves from compact dark matter objects in the solar system
Creators: name: Horowitz, C. J.
name: Papa, M. A.
name: Reddy, S.
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Dark matter could be composed of compact dark objects (CDOs). A close binary of CDOs orbiting in the interior of solar system bodies can be a loud source of gravitational waves (GWs) for the LIGO and VIRGO detectors. We perform the first search ever for this type of signal and rule out close binaries, with separations of order 300 m, orbiting near the center of the Sun with GW frequencies (twice the orbital frequency) between 50 and 550 Hz and CDO masses above $\approx 10^{-9} M_\odot$. This mass limit is eight orders of magnitude lower than the mass probed in a LIGO search at extra galactic distances.
description: 5 pages, 3 figures, Phys. Lett. B in press
Statistical Physics of Irregular Low-Density Parity-Check Codes
Creators: name: Vicente, Renato
name: Saad, David
name: Kabashima, Yoshiyuki
Publisher: name: arXiv
Year: 1999
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: Low-density parity-check codes with irregular constructions have been recently shown to outperform the most advanced error-correcting codes to date. In this paper we apply methods of statistical physics to study the typical properties of simple irregular codes. We use the replica method to find a phase transition which coincides with Shannon's coding bound when appropriate parameters are chosen. The decoding by belief propagation is also studied using statistical physics arguments; the theoretical solutions obtained are in good agreement with simulations. We compare the performance of irregular with that of regular codes and discuss the factors that contribute to the improvement in performance.
description: 20 pages, 9 figures, revised version submitted to JPA
Demonstrating Advantages of Neuromorphic Computation: A Pilot Study
Creators: name: Wunderlich, Timo
name: Kungl, Akos F.
name: Müller, Eric
name: Hartel, Andreas
name: Stradmann, Yannik
name: Aamir, Syed Ahmed
name: Grübl, Andreas
name: Heimbrecht, Arthur
name: Schreiber, Korbinian
name: Stöckel, David
name: Pehle, Christian
name: Billaudelle, Sebastian
name: Kiene, Gerd
name: Mauch, Christian
name: Schemmel, Johannes
name: Meier, Karlheinz
name: Petrovici, Mihai A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: Emerging Technologies (cs.ET)
subject: FOS: Computer and information sciences

description: Neuromorphic devices represent an attempt to mimic aspects of the brain's architecture and dynamics with the aim of replicating its hallmark functional capabilities in terms of computational power, robust learning and energy efficiency. We employ a single-chip prototype of the BrainScaleS 2 neuromorphic system to implement a proof-of-concept demonstration of reward-modulated spike-timing-dependent plasticity in a spiking network that learns to play the Pong video game by smooth pursuit. This system combines an electronic mixed-signal substrate for emulating neuron and synapse dynamics with an embedded digital processor for on-chip learning, which in this work also serves to simulate the virtual environment and learning agent. The analog emulation of neuronal membrane dynamics enables a 1000-fold acceleration with respect to biological real-time, with the entire chip operating on a power budget of 57mW. Compared to an equivalent simulation using state-of-the-art software, the on-chip emulation is at least one order of magnitude faster and three orders of magnitude more energy-efficient. We demonstrate how on-chip learning can mitigate the effects of fixed-pattern noise, which is unavoidable in analog substrates, while making use of temporal variability for action exploration. Learning compensates imperfections of the physical substrate, as manifested in neuronal parameter variability, by adapting synaptic weights to match respective excitability of individual neurons.
description: Added measurements with noise in NEST simulation, add notice about journal publication. Frontiers in Neuromorphic Engineering (2019)
Combining implementation intentions and monetary incentives to reduce alcohol use: a failed generalization to a public bar context
Creators: name: Liu, Yang
name: van den Wildenberg, Wery P.M.
name: Ridderinkhof, K. Richard
name: Wiers, Reinout W.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Virology

description: Implementation intentions have been demonstrated to reduce alcohol use in retrospective self-report measures. It remains unclear, however, whether they can moderate drinking in a challenging naturalistic context. We examined this by studying the effects of implementation intentions on alcohol use in a bar. One hundred and twenty-one participants visiting a local bar were randomized over three conditions: control, motivational trigger, and motivational trigger plus implementation intentions. Those in the motivational trigger group were motivated to reduce drinking, and the combined intervention group made additional alcohol-related implementation intentions. We assessed participants’ pre- and post-intervention breath alcohol concentrations, their post-intervention drinking behavior over one hour, and measures of trait impulsivity and reward sensitivity. To predict post-intervention drinking, multiple hierarchical regression was used. Neither the motivational trigger nor the added implementation intentions reduced drinking. Across treatment groups, trait impulsivity predicted alcohol consumption. The present study showed that motivational trigger and implementation intentions failed to reduce alcohol use in a naturalistic setting. Potential reasons, implications, and limitations are discussed. This first attempt demonstrates that implementation intentions aimed at moderation are not as easily implemented in a public high-risk context.
Glossoscolecidae
Creators: name: Bruz, Lilianne Dos Santos Maia
name: Santos, Alessandra
name: Demetrio, Wilian C.
name: Primo, Daniele De Freitas
name: Feliciano, Luana Priscila
name: Fernandes, Carlos Henrique
name: Bartz, Marie L. C.
name: Bernardi, Alberto Carlos De Campo
name: Pezzopane, José Ricardo Macedo
name: Brown, George Gardner
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Clitellata
Crassiclitellata
Glossoscolecidae

description: Glossoscolecidae juveniles  BRSP0747, 4 juveniles in SP; February 22, 2018; L.S. Maia-Bruz, W.C. Demetrio, A. Santos, M.L.C. Bartz, L.P. Feliciano, D.F. Primo, C.H. Fernandes, collectors.
description: Published as part of Bruz, Lilianne Dos Santos Maia, Santos, Alessandra, Demetrio, Wilian C., Primo, Daniele De Freitas, Feliciano, Luana Priscila, Fernandes, Carlos Henrique, Bartz, Marie L. C., Bernardi, Alberto Carlos De Campo, Pezzopane, José Ricardo Macedo & Brown, George Gardner, 2023, Earthworms in various agricultural and forest ecosystems in São Carlos-SP Brazil, pp. 324-335 in Zootaxa 5255 (1) on page 330, DOI: 10.11646/zootaxa.5255.1.26, http://zenodo.org/record/7744974
Fractal Conductance Fluctuations in Gold--Nanowires
Creators: name: Hegger, Helmut
name: Hecker, Klaus
name: Reckziegel, Gernot
name: Freimuth, Axel
name: Huckestein, Bodo
name: Janssen, Martin
name: Tuzinski, Rüdiger
Publisher: name: arXiv
Year: 1996
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: A detailed analysis of magneto-conductance fluctuations of quasiballistic gold-nanowires of various lengths is presented. We find that the variance $ = < (G(B)-G(B+ΔB))^2>$ when analyzed for $ΔB$ much smaller than the correlation field $B_c$ varies according to $\propto ΔB^γ$ with $γ< 2$ indicating that the graph of $G$ vs. $B$ is fractal. We attribute this behavior to the existence of long-lived states arising from chaotic trajectories trapped close to regular classical orbits. We find that $γ$ decreases with increasing length of the wires.
description: 5 pages, Revtex with epsf, 4 Postscript figures, final version accepted as Phys. Rev. Lett
Disparities and reverse disparities in HPV vaccination: A systematic review and meta-analysis
Creators: name: Brewer N.T
name: Calo W.A
name: Spencer J.C
Publisher: name: Academic Press Inc.
Year: 2019

description: Studies disagree about whether racial and ethnic groups have lower or higher human papillomavirus (HPV) vaccination uptake, an important issue given large disparities in some HPV cancers. We sought to characterize and explain racial and ethnic differences in HPV vaccination. We systematically searched PubMed, CINAHL, Embase, and Web of Science to identify US studies through mid-2017 reporting associations of race and ethnicity with HPV vaccination. We identified 118 studies (n = 3,095,486) published in English that reported HPV vaccine initiation or follow-through in the US from which we could calculate effect sizes. We used random effects meta-analysis to synthesize effect sizes for comparisons of Whites or non-Hispanics to Blacks, Hispanics, Asians, or all minority groups combined. Studies showed no racial or ethnic differences in HPV vaccine initiation overall. However, when restricting to studies using provider-verified vaccination data, minorities were 6.1% [3.3%–8.8%] more likely than Whites to initiate HPV vaccination. Advantages were larger for Hispanics, males, and younger samples (age < 18). In contrast, minorities were 8.6% [5.6%, 11.7%], less likely than Whites to follow-through with the full HPV vaccine series, a disparity present across all participant and study characteristics. More recent studies found larger advantages for racial and ethnic minorities in HPV vaccine initiation and smaller disparities in follow-through. In summary, high-quality studies found racial and ethnic minorities are more likely to initiate but less likely to follow-through with HPV vaccination, a clear finding that self-report studies obscure. Higher HPV vaccine initiation among minorities suggests potential reductions in HPV cancer disparities.
Dilatancy and Friction in sheared granular media
Creators: name: Lacombe, F.
name: Zapperi, S.
name: Herrmann, H. J.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We introduce a simple model to describe the frictional properties of granular media under shear. We model the friction force in term of the horizontal velocity v and the vertical position z of the slider, interpreting z as a constitutive variable characterizing the contact. Dilatancy is shown to play an essential role in the dynamic, inducing a stick-slip instability at low velocity. We compute the phase diagram, analyze numerically the model for a wide range of parameters and compare our results with experiments on dry and wet granular media, obtaining a good agreement. In particular, we reproduce the hysteretic velocity dependence of the frictional force.
description: 10 pages
Keyless Semi-Quantum Point-to-point Communication Protocol with Low Resource Requirements
Creators: name: Lu, Haoye
name: Barbeau, Michel
name: Nayak, Amiya
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Full quantum capability devices can provide secure communications, but they are challenging to make portable given the current technology. Besides, classical portable devices are unable to construct communication channels resistant to quantum computers. Hence, communication security on portable devices cannot be guaranteed. Semi-Quantum Communication (SQC) attempts to break the quandary by lowering the receiver's required quantum capability so that secure communications can be implemented on a portable device. However, all SQC protocols have low qubit efficiency and complex hardware implementations. The protocols involving quantum entanglement require linear Entanglement Preservation Time (EPT) and linear quregister size. In this paper, we propose two new keyless SQC protocols that address the aforementioned weaknesses. They are named Economic Keyless Semi-Quantum Point-to-point Communication (EKSQPC) and Rate Estimation EKSQPC (REKSQPC). They achieve theoretically constant minimal EPT and quregister size, regardless of message length. We show that the new protocols, with low overhead, can detect Measure and Replay Attacks (MRAs). REKSQDC is tolerant to transmission impairments and environmental perturbations. The protocols are based on a new quantum message transmission operation termed Tele-Fetch. Like QKD, their strength depends on physical principles rather than mathematical complexity.
Additional file 1 of Early warning of bloodstream infection in elderly patients with circulating microparticles
Creators: name: Liu, Tingting
name: Wang, Jiang
name: Yuan, Yaping
name: Wu, Jionghe
name: Wang, Chao
name: Gu, Yueqin
name: Li, Hongxia
Publisher: name: figshare
Year: 2021
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Computational Biology

description: Additional file 1:
Twitter Sentiment Analysis
Creators: name: Priyanka, Vedurumudi
Publisher: name: Zenodo
Year: 2021
Subjects: deep learning
machine learning
python
keras

description: In this report, address the problem of sentiment classification on twitter dataset. used a number of machine learning and deep learning methods to perform sentiment analysis. In the end, used a majority vote ensemble method with 5 of our best models to achieve the classification accuracy of 83.58% on kaggle public leaderboard.
description: {"references": ["Pang, B., Lee, L.: Opinion mining and sentiment analysis. Foundations and Trends in Information Retrieval 2(1-2), 1\u2013135 (2008"]}
Megascolecidae
Creators: name: Bruz, Lilianne Dos Santos Maia
name: Santos, Alessandra
name: Demetrio, Wilian C.
name: Primo, Daniele De Freitas
name: Feliciano, Luana Priscila
name: Fernandes, Carlos Henrique
name: Bartz, Marie L. C.
name: Bernardi, Alberto Carlos De Campo
name: Pezzopane, José Ricardo Macedo
name: Brown, George Gardner
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Clitellata
Opisthopora
Megascolecidae

description: Megascolecidae juveniles  BRSP0685 and BRSP0817 (1 juvenile each) in ASP; February 21, 2018; L.S. Maia-Bruz, W.C. Demetrio, A. Santos, G.G. Brown, M.L.C. Bartz, L.P. Feliciano, D.F. Primo, C.H. Fernandes, collectors. BRSP0722, 2 juveniles in CP; February 23, 2018; L.S. Maia-Bruz, W.C. Demetrio, A. Santos, G.G. Brown, M.L.C. Bartz, L.P. Feliciano, D.F. Primo, C.H. Fernandes, collectors. BRSP0771, 1 juvenile in IP; February 23, 2018; L.S. Maia-Bruz, W.C. Demetrio, A. Santos, M.L.C. Bartz, L.P. Feliciano, D.F. Primo, C.H. Fernandes, collectors.
description: Published as part of Bruz, Lilianne Dos Santos Maia, Santos, Alessandra, Demetrio, Wilian C., Primo, Daniele De Freitas, Feliciano, Luana Priscila, Fernandes, Carlos Henrique, Bartz, Marie L. C., Bernardi, Alberto Carlos De Campo, Pezzopane, José Ricardo Macedo & Brown, George Gardner, 2023, Earthworms in various agricultural and forest ecosystems in São Carlos-SP Brazil, pp. 324-335 in Zootaxa 5255 (1) on page 330, DOI: 10.11646/zootaxa.5255.1.26, http://zenodo.org/record/7744974
Magnetic Ball Chain Robots for Cardiac Arrhythmia Treatment
Creators: name: Pittiglio, Giovanni
name: Leuenberger, Fabio
name: Mencattelli, Margherita
name: McCandless, Max
name: O'Leary, Edward
name: Dupont, Pierre E.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Robotics (cs.RO)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This paper introduces a novel magnetic navigation system for cardiac ablation. The system is formed from two key elements: a magnetic ablation catheter consisting of a chain of spherical permanent magnets; and an actuation system comprised of two cart-mounted permanent magnets undergoing pure rotation. The catheter design enables a large magnetic content with the goal of minimizing the footprint of the actuation system for easier integration with the clinical workflow. We present a quasi-static model of the catheter, the design of the actuation units, and their control modalities. Experimental validation shows that we can use small rotating magnets (119mm diameter) to reach cardiac ablation targets while generating clinically-relevant forces. Catheter control using a joystick is compared with manual catheter control. blue While total task completion time is similar, smoother navigation is observed using the proposed robotic system. We also demonstrate that the ball chain can ablate heart tissue and generate lesions comparable to the current clinical ablation catheters.
description: in IEEE Transactions on Medical Robotics and Bionics, 2024
Disparities in premature cardiac death among us counties from 1999–2017: Temporal trends and key drivers
Creators: name: Zhang, L
name: Zheng, Z.-J
name: Song, S
name: Labresh, K.A
name: Jin, Y
name: Smith, Jr., S.C
name: Trisolini, M.G
Publisher: name: American Heart Association Inc.
Year: 2020

description: BACKGROUND: Disparities in premature cardiac death (PCD) might stagnate the progress toward the reduction of PCD in the United States and worldwide. We estimated disparities across US counties in PCD rates and investigated county-level factors related to the disparities. METHODS AND RESULTS: We used US mortality data for cause-of-death and demographic data from death certificates and county-level characteristics data from multiple databases. PCD was defined as any death that occurred at an age between 35 and 74 years with an underlying cause of death caused by cardiac disease based on International Classification of Diseases, Tenth Revision (ICD-10), codes. Of the 1 598 173 PCDs that occurred during 1999–2017, 60.9% were out of hospital. Although the PCD rates declined from 1999–2017, the proportion of out-of-hospital PCDs among all cardiac deaths increased from 58.3% to 61.5%. The geographic disparities in PCD rates across counties widened from 1999 (Theil index=0.10) to 2017 (Theil index=0.23), and within-state differences accounted for the majority of disparities (57.4% in 2017). The disparities in out-of-hospital PCD rates (and in-hospital PCD rates) associated with demographic composition were 36.51% (and 37.51%), socioeconomic features were 18.64% (and 18.36%), healthcare environment were 18.64% (and 13.90%), and population health status were 23.73% (and 30.23%). CONCLUSIONS: Disparities in PCD rates exist across US counties, which may be related to the decelerated trend of decline in the rates among middle-aged adults. The slower declines in out-of-hospital rates warrants more precision targeting and sustained efforts to ensure progress at better levels of health (with lower PCD rates) against PCD.
Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis
Creators: name: Wang J
name: Dotti G
name: Li H
name: Meng H
name: Bryan Bell R
name: Li R
name: Chen G
name: Wen D
name: Wang Z
name: Gu Z
name: Chen Z
name: Ci T
name: Gu Z
Publisher: name: Nature Research
Year: 2021

description: Although therapies of cancer are advancing, it remains challenging for therapeutics to reach the sites of metastasis, which accounts for majority of cancer associated death. In this study, we have developed a strategy that guides an anti-programmed cell death-ligand 1 (aPDL1) antibody to accumulate in metastatic lesions to promote anti-tumour immune responses. Briefly, we have developed a combination in which Vadimezan disrupts tumour blood vessels of tumour metastases and facilitates the recruitment and activation of adoptively transferred aPDL1-conjugated platelets. In situ activated platelets generate aPDL1-decorated platelet-derived microparticles (PMP) that diffuse within the tumour and elicit immune responses. The proposed combination increases 10-fold aPDL1 antibody accumulation in lung metastases as compared to the intravenous administration of the antibody and enhances the magnitude of immune responses leading to improved antitumour effects.
title: Atlas Factorial
Creators: name: Mincks, Christian Michael
Publisher: name: George Mason University
Year: 2021
Subjects: subject: Greek mythology
subject: Farce
subject: Metaphysics
subject: Comedy
subject: Novel

description: This thesis has been embargoed for 10 years. It will not be available until May 2030 at the earliest.
description: Atlas Factorial is a metaphysical, episodic adventure novel loosely retelling the Greek myth of the Titan Atlas. Atlas, in this adaptation, has been floating for an eternity in the vacuum of space carrying the world upon his back when Hercules arrives and requests his help in collecting the Golden Apples from the Garden of the Hesperides, a trio of sunlight nymphs who are Atlas’s daughters. To get there, the duo must first pass through endless, compartmentalized Voids that house various iterations of figures from Greek mythology. As Atlas and Hercules explore these Voids, they encounter alternate-universe versions of Atlas, many of whom are derived from conflicting depictions of him in surviving historical records. As Atlas faces paradox after paradox, he must construct his own identity, whether as revolutionary or oppressor, thinker or feeler. However, when he gets a taste of fatherhood, he is forced to decide once and for all to follow the path laid out for him or abandon fate for his family.
Additional file 2 of Early warning of bloodstream infection in elderly patients with circulating microparticles
Creators: name: Liu, Tingting
name: Wang, Jiang
name: Yuan, Yaping
name: Wu, Jionghe
name: Wang, Chao
name: Gu, Yueqin
name: Li, Hongxia
Publisher: name: figshare
Year: 2021
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Computational Biology

description: Additional file 2:
Spectrum of Background X-rays from Moduli Dark Matter
Creators: name: Asaka, T.
name: Hashiba, J.
name: Kawasaki, M.
name: Yanagida, T.
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We examine the $X$-ray spectrum from the decay of the dark-matter moduli with mass $\sim {\cal O}(100)$keV, in particular, paying attention to the line spectrum from the moduli trapped in the halo of our galaxy. It is found that with the energy resolution of the current experiments ($\sim 10$%) the line intensity is about twice stronger than that of the continuum spectrum from the moduli that spread in the whole universe. Therefore, in the future experiments with higher energy resolutions it may be possible to detect such line photons. We also investigate the $γ$-ray spectrum emitted from the decay of the multi-GeV moduli. It is shown that the emitted photons may form MeV-bump in the $γ$-ray spectrum. We also find that if the modulus mass is of the order of 10 GeV, the emitted photons at the peak of the continuum spectrum loses their energy by the scattering and the shape of the spectrum is significantly changed, which makes the constraint weaker than that obtained in the previous works.
description: 14 pages (RevTeX file) including four postscript figures, reviced version to be published in Physical Review D
Additional file 1 of Preliminary study on the diagnosis of NK stress based on the puncture mechanical characteristics of cucumber stem
Creators: name: Liu, Yong
name: Wang, Yafei
name: Wang, Bin
name: Shi, Qiang
name: Mao, Hanping
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 1: Fig. S1. Superdepth microscope and samples microscopic observation. Fig. S2. Micro CT and stem wound measurement. During scanning, put the stem sample into the container as shown in Figure S2-b and fix it with foam plate. Fig. S3. Puncture test with texture analyzer. Fig. S4. Biological atomic force microscope. Fig. S5. Method flowchart.
The Skyrme Energy Functional and Naturalness
Creators: name: Furnstahl, R. J.
name: Hackworth, James C.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Recent studies show that successful relativistic mean-field models of nuclei are consistent with naive dimensional analysis and naturalness, as expected in low-energy effective field theories of quantum chromodynamics. The nonrelativistic Skyrme energy functional is found to have similar characteristics.
description: 8 pages, REVTeX 3.0 with epsf.sty, plus 2 figures
title: Letter and Enclosure: C. Harrison Mann, Jr. and Charles R. Fenwick to William H. Natcher, December 12, 1968
Creators: name: Mann, Charles Harrison, Jr., 1908-1977
name: Fenwick, Charles R.
Publisher: name: George Mason University
Year: 2007
Subjects: subject: Traffic
subject: Transportation

description: Letter: 2 pgs, typescript signed, 8.5" x 11" (21.6 cm x 27.9 cm); Article, page 1: black & white, 8.5" x 13" (21.6 cm x 33 cm); Article, page 2, black & white, 13" x 8.8" (33 cm x 22.4 cm)
description: Letter from C. Harrison Mann, Jr. and Sen. Charles R. Fenwick to Rep. William H. Natcher regarding the actions of the National Capital Planning Committee in eliminating the proposed Three Sisters Bridge. Enclosed with the letter is a related newspaper clipping from the December 12, 1968 edition of the Washington Post, "DC Planners Cut Commuter Roads" by Jack Eisen. C. Harrison Mann, Jr. Collection 62.02
Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer
Creators: name: Bader, G.D
name: Li, H
name: Jiang, Z
name: Liu, J.C
name: Ghanbari-Azarnier, R
name: Vorobieva, I
name: Ben-David, Y
name: Egan, S.E
name: Skowron, P
name: Mwewa, E
name: Taylor, M.D
name: Ali, A
name: Woodgett, J.R.
name: Shrestha, M
name: Chung, P.E.D
name: Koritzinsky, M
name: Dupuy, A
name: Ju, Y.J
name: Perou, C.M.
name: Wang, D.-Y
name: Zacksenhaus, E
Publisher: name: Nature Research
Year: 2023

description: Metastatic breast-cancer is a major cause of death in women worldwide, yet the relationship between oncogenic drivers that promote metastatic versus primary cancer is still contentious. To elucidate this relationship in treatment-naive animals, we hereby describe mammary-specific transposon-mutagenesis screens in female mice together with loss-of-function Rb, which is frequently inactivated in breast-cancer. We report gene-centric common insertion-sites (gCIS) that are enriched in primary-tumors, in metastases or shared by both compartments. Shared-gCIS comprise a major MET-RAS network, whereas metastasis-gCIS form three additional hubs: Rho-signaling, Ubiquitination and RNA-processing. Pathway analysis of four clinical cohorts with paired primary-tumors and metastases reveals similar organization in human breast-cancer with subtype-specific shared-drivers (e.g. RB1-loss, TP53-loss, high MET, RAS, ER), primary-enriched (EGFR, TGFβ and STAT3) and metastasis-enriched (RHO, PI3K) oncogenic signaling. Inhibitors of RB1-deficiency or MET plus RHO-signaling cooperate to block cell migration and drive tumor cell-death. Thus, targeting shared- and metastasis- but not primary-enriched derivers offers a rational avenue to prevent metastatic breast-cancer.
Bipartite fidelity of critical dense polymers
Creators: name: Parez, Gilles
name: Morin-Duchesne, Alexi
name: Ruelle, Philippe
Publisher: name: arXiv
Year: 2019
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We investigate the bipartite fidelity $\mathcal F_d$ for a lattice model described by a logarithmic CFT: the model of critical dense polymers. We define this observable in terms of a partition function on the pants geometry, where $d$ defects enter at the top of the pants lattice and exit in one of the legs. Using the correspondence with the XX spin chain, we obtain an exact closed-form expression for $\mathcal F_d$ and compute the leading terms in its $1/N$ asymptotic expansion as a function of $x = N_A/N$, where $N$ is the lattice width at the top of the pants and $N_A$ is the width of the leg where the defects exit. We find an agreement with the results of Stéphan and Dubail for rational CFTs, with the central charge and conformal weights specialised to $c=-2$ and $Δ= Δ_{1,d+1} = d(d-2)/8$. We compute a second instance $\mathcal {\tilde F}_2$ of the bipartite fidelity for $d=2$ by imposing a different rule for the connection of the defects. In the conformal setting, this choice corresponds to inserting two boundary condition changing fields of weight $Δ= 0$ that are logarithmic instead of primary. We compute the asymptotic expansion in this case as well and find a simple additive correction compared to $\mathcal F_2$, of the form $-2\log((1+x)/(2\sqrt{x}))$. We confirm this lattice result with a CFT derivation and find that this correction term is identical for all logarithmic theories, independently of $c$ and $Δ$.
description: 35 pages. v2: minor changes
Numerical simulations of scattering speckle from phase ordering systems
Creators: name: Brown, Gregory
name: Rikvold, Per Arne
name: Grant, Martin
Publisher: name: arXiv
Year: 1996
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: The scattering of coherent X-rays from dynamically evolving systems is currently becoming experimentally feasible. The scattered beam produces a pattern of bright and dark speckles, which fluctuate almost independently in time and can be used to study the dynamics of the system. Here we report large-scale computer simulations of the speckle dynamics for a phase ordering system, using a two-dimensional model quenched through an order--disorder transition into the two-phase regime. The intensity at each wave vector ${\bf k}$ is found to be an exponentially distributed random variable. The scaling hypothesis is extended to the two-time correlation function of the scattering intensity at a given wave vector, $Corr({\bf k};t_1,t_2)$. The characteristic decay time difference for the correlation function, $|t_1 - t_2|_c$, is found to scale as $k|t_1 + t_2|^{1/2}$.
description: 11 Pages, RevTex, 6 PostScript Figures Accepted to Physica A
title: ADCO, Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Cart. 168 (11 H 66), f. 0044v
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2010
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 168 (11 H 66), f. 0044v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 168 (11 H 66), f. 0044v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopes
Creators: name: Baric R.S
name: Chuang G.-Y
name: Shi W
name: Tully E.S
name: Brewer-Jensen P.D
name: Gorman J
name: Kwong P.D.
name: Edwards C.E
name: Mallory M.L
name: Lindesmith L.C
name: Schön A
name: Verardi R
name: Tsybovsky Y
name: Ou L
name: Georgiou G
Publisher: name: Nature Research
Year: 2020

description: Human noroviruses are non-enveloped, single-strand RNA viruses that cause pandemic outbreaks of acute gastroenteritis. A bivalent vaccine containing GI.1 and GII.4 virus-like particles (VLPs) has been shown to be safe and highly immunogenic, but its efficacy and durability have been limited. Here, we show that norovirus GI.1 VLPs are unstable and contain a substantial fraction of dissociated VLP components. Broadly reactive, non-neutralizing antibodies isolated from vaccinated donors bound to the dissociated components, but not to the intact VLPs. Engineering of interprotomer disulfide bonds within the shell domain prevented disassembly of the VLPs, while preserving antibody accessibility to blockade epitopes. Without adjuvant, mice immunized with stabilized GI.1 VLPs developed faster blockade antibody titers compared to immunization with wild-type GI.1 VLPs. In addition, immunization with stabilized particles focused immune responses toward surface-exposed epitopes and away from occluded epitopes. Overall, disulfide-stabilized norovirus GI.1 VLPs elicited improved responses over the non-disulfide-stabilized version, suggesting their promise as candidate vaccines.
Ocnerodrilidae
Creators: name: Bruz, Lilianne Dos Santos Maia
name: Santos, Alessandra
name: Demetrio, Wilian C.
name: Primo, Daniele De Freitas
name: Feliciano, Luana Priscila
name: Fernandes, Carlos Henrique
name: Bartz, Marie L. C.
name: Bernardi, Alberto Carlos De Campo
name: Pezzopane, José Ricardo Macedo
name: Brown, George Gardner
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Clitellata
Haplotaxida
Ocnerodrilidae

description: Family Ocnerodrilidae  BRSP0768, 7 adults in IP; February 23, 2018; M.L.C. Bartz, collector.
description: Published as part of Bruz, Lilianne Dos Santos Maia, Santos, Alessandra, Demetrio, Wilian C., Primo, Daniele De Freitas, Feliciano, Luana Priscila, Fernandes, Carlos Henrique, Bartz, Marie L. C., Bernardi, Alberto Carlos De Campo, Pezzopane, José Ricardo Macedo & Brown, George Gardner, 2023, Earthworms in various agricultural and forest ecosystems in São Carlos-SP Brazil, pp. 324-335 in Zootaxa 5255 (1) on page 331, DOI: 10.11646/zootaxa.5255.1.26, http://zenodo.org/record/7744974
Collaborative Climate and Knowledge Sharing among ESP Teachers: A Mixed Method Study
Creators: name: Farahian, Majid
name: Parhamnia, Farshad
Publisher: name: figshare
Year: 2021
Subjects: subject: 200303 English as a Second Language
subject: FOS: Languages and literature

description: Research on teacher collaboration emphasizes the key role of collaborative culture for teachers’ functioning; however, there is little empirical evidence to investigate its relationship with knowledge sharing among university ESP teachers. In the present study, the relationship between EFL teachers’ collaborative climate and knowledge sharing was sought. The data were collected through two surveys of 328 Iranian ESP teachers. A Pearson correlation was carried out to investigate the relationship between the two variables of the study. A multiple regression analysis was also run to examine if ESP teachers’ collaborative climate predicts their knowledge sharing. A follow-up interview with 13 ESP teachers was conducted to consolidate the findings and explore the contribution of teachers’ collaborative climate to their knowledge sharing. The Pearson correlation coefficient test demonstrated a significant positive correlation for four measures (organizational culture, the head of department, teachers’ attitude, workgroup support), and the collaborative climate. The results of the multiple regression also indicated that four subscales of collaborative climate were the predictors of ESP teachers’ attitude towards knowledge sharing. Analysis of the interview data, on the other hand, indicated how teachers’ collaborative climate contributes to their knowledge sharing through one of the four main sources, namely helpful atmosphere, encouragement received from the heads of departments, the expectation of reward, and work group support. In line with these findings, several practical recommendations were offered.
Resolution of the Sign Problem for a Frustrated Triplet of Spins
Creators: name: Hen, Itay
Publisher: name: arXiv
Year: 2018
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a mechanism for solving the `negative sign problem'---the inability to assign non-negative weights to quantum Monte Carlo configurations---for a toy model consisting of a frustrated triplet of spin-$1/2$ particles interacting antiferromagnetically. The introduced technique is based on the systematic grouping of the weights of the recently developed off-diagonal series expansion of the canonical partition function [Phys. Rev. E 96, 063309 (2017)]. We show that while the examined model is easily diagonalizable, the sign problem it encounters can nonetheless be very pronounced, and we offer a systematic mechanism to resolve it. We discuss the generalization of the suggested scheme and the steps required to extend it to more general and larger spin models.
description: 12 pages, 5 figures