cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Two new chromanone acids from the stem bark of Calophyllum peekelii Lauterb
Creators: name: Tjahjandarie, Tjitjik Srie
name: Nugroho, Wisnu Aji Setyo
name: Palgunadi, Hady
name: Saputri, Ratih Dewi
name: Tanjung, Mulyadi
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: Three chromanone acids were isolated from the stem bark of Calophyllum peekelii Lauterb. Among them are two new chromanone acids, calopeekelioic acids A (1) and B (2), along with calolongic acid (3), Their structures were established by analyzing a combination of HRESIMS, 1 D, and 2 D NMR spectra. Chromanone acids 1-3 were evaluated for their antiplasmodial activity against Plasmodium falciparum strain 3D7. Compounds 1-2 showed high activity with an IC50 value of 1.70 and 1.01 µg/mL, respectively.
On the Morpho-Syntax of Existential Sentences in Romance based Creoles
Creators: name: Franco, Ludovico
name: Lorusso, Paolo
Publisher: name: Quaderni di Linguistica e Studi Orientali
Year: 2018

description: In this paper we provide a comprehensive comparative overview of existentials sentences in Romance Creoles. Based on our empirical investigation, we also provide a theoretical analysis of existential constructions which mimic ‘transitive’ possession. Specifi cally, we assume that the pervasiveness of a predicative possession strategy for existentials in Creoles has refl exes in their syntax, for which a possession confi guration, building on recent work of Manzini and Franco (2016), Franco and Manzini (2017, to appear), Franco and Lorusso (2018) will be draw. In essence, we argue that the ‘contextual domain’ of existentials (see Francez 2007; 2009) can be encoded as the possessor of a (transitive) have predicate including the pivot as its internal argument (cf. Manzini and Savoia 2005), with the coda which is (optionally) introduced as an adjunct encoding a further possessor (‘locative’ inclusor) of the predicate (cf. McNally 1992).
description: Quaderni di Linguistica e Studi Orientali, Vol 4 (2018)
Age-Related Macular Degeneration and Long-Term Risk of Stroke Subtypes
Creators: name: Ikram, M. K.
name: Klein, R.
name: Mitchell, P.
name: Couper, D. J.
name: Wong, T. Y.
name: Sharrett, A. R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: We examined the relationship of age-related macular degeneration (AMD) with incident stroke, including stroke subtypes of cerebral infarction and intracerebral haemorrhage (ICH).
Exact probes of orientifolds
Creators: name: Fiol, Bartomeu
name: Garolera, Blai
name: Torrents, Genis
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We compute the exact vacuum expectation value of circular Wilson loops for Euclidean ${\cal N}=4$ super Yang-Mills with $G=SO(N),Sp(N)$, in the fundamental and spinor representations. These field theories are dual to type IIB string theory compactified on $AdS_5\times {\mathbb R} {\mathbb P}^5$ plus certain choices of discrete torsion, and we use our results to probe this holographic duality. We first revisit the LLM-type geometries having $AdS_5\times {\mathbb R} {\mathbb P}^5$ as ground state. Our results clarify and refine the identification of these LLM-type geometries as bubbling geometries arising from fermions on a half harmonic oscillator. We furthermore identify the presence of discrete torsion with the one-fermion Wigner distribution becoming negative at the origin of phase space. We then turn to the string world-sheet interpretation of our results and argue that for the quantities considered they imply two features: first, the contribution coming from world-sheets with a single crosscap is closely related to the contribution coming from orientable world-sheets, and second, world-sheets with two crosscaps don't contribute to these quantities.
description: 28 pages. v2: Added references
Carotid Arterial Wall Characteristics Are Associated With Incident Ischemic Stroke But Not Coronary Heart Disease in the Atherosclerosis Risk in Communities (ARIC) Study
Creators: name: Virani, S. S.
name: Chambless, L.
name: Yang, E. Y.
name: Boerwinkle, E.
name: Sharrett, A. R.
name: Ballantyne, C. M.
name: Liu, X.
name: Tang, Z.
name: Nambi, V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Ultrasound measurements of arterial stiffness are associated with atherosclerosis risk factors, but limited data exist on their association with incident cardiovascular events. We evaluated the association of carotid ultrasound derived arterial stiffness measures with incident coronary heart disease (CHD) and ischemic stroke in the ARIC study.
Oblique Serial Verbs in Creole/Pidgin Languages
Creators: name: Franco, Ludovico
Publisher: name: Quaderni di Linguistica e Studi Orientali
Year: 2018

description: Th is paper focuses on the syntax of (argument introducing/valency increasing) serial verbs in Creole/Pidgin languages, providing empirical arguments for the model of grammatical relations advanced in a series of recent works by Manzini and Savoia (2011a, 2011b), Manzini and Franco (2016), Franco and Manzini (2017a, 2017b), Manzini et al. (to appear a, b). Th ese authors lay out an analysis of the syntax and interpretation of dative to, instrumental with and Diff erential Object Marking (DOM) relators, based on the assumption that these elements are predicates endowed with an elementary interpretive content interacting with the internal organization of the event. We assume that these oblique relators, expressing a primitive elementary part-whole/ possession relation, may be instantiated also by serial (light) verbs in the grammar of natural languages. We provide a formal approach to cross-categorial variation in argument marking, trying to outline a unifi ed morpho-syntactic template, in which so-called ‘cases’ do not confi gure a specialized linguistic lexicon of functional features/categories – on the contrary they help us outline an underlying ontology of natural languages, of which they pick up some of the most elementary relations. Such primitive relations can be expressed by different lexical means (e.g. case, adpositions, light verbs, etc.).
description: Quaderni di Linguistica e Studi Orientali, Vol 4 (2018)
Morphosyntactic Reorganization Phenomena in Arbëresh Dialects: The Neuter
Creators: name: Baldi, Benedetta
name: Savoia, Leonardo M.
Publisher: name: Quaderni di Linguistica e Studi Orientali
Year: 2018

description: Italo-Albanian communities show diff erent degrees of mixing between Arbresh, the local Albanian dialect, and the Romance variety in contact. In some Arberesh dialects the mixing is extensive, aff ecting lexicon, morpho-syntax and phonology. Contact and bilingualism favour changes in the internal organization of the grammar, as generally in the creolization processes (Savoia 2010; Manzini and Savoia 2015; Baldi and Savoia 2016). This contribution addresses the so-called neuter inflection that Arberesh dialects spoken in Southern Italian communities preserve, an inflection no longer surviving in standard and other varieties of Albanian, where masculine morphology has replaced it. Th e coincidence between the specialized -t neuter inflection in nominative and accusative and the plural inflection -t characterizing North-Calabrian Arberesh led Manzini and Savoia (2017a, 2017b, forthcoming) to connect this morphology with the interpretive properties associated to mass denotation. We hold on to this proposal that has the merit to explain the relation between plural and mass properties. In North-Lucanian and Apulian Arberesh systems this sub-set of nouns, while maintaining the infl ection -t, agrees in feminine. Th is result can be understood as a consequence of the reorganization that aff ected these partially mixed grammars, where the original morpho-syntactic mechanisms have been lost or modified.
description: Quaderni di Linguistica e Studi Orientali, Vol 4 (2018)
Proximate composition, fungal isolation and contamination of aflatoxin B1 in chickpea seeds from the Punjab, Pakistan
Creators: name: Tania, Ayesha
name: Akram, Abida
name: Hanif, Nafeesa Qudsia
name: Ajmal, Maryam
name: Seerat, Wajiha
name: Nijabat, Aneela
name: Mehak, Asma
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Chickpea, Cicer arietinum L., is a nutrient rich crop that is widely cultivated and consumed in Pakistan. However, chickpea is highly prone to fungal growth leading to contamination with aflatoxins, the most potent carcinogen found in nature. In this study, fifty chickpea seed samples were collected from the local markets of the Punjab, Pakistan, to evaluate their nutritional quality, fungal and AFB1 contamination. Proximate analysis suggested that chickpea seeds contained 5.5–6.93% moisture, 62.24–63.24% carbohydrates, 22.75–23.44% protein, 4.99–5.4% fat, 5.62–5.84% fiber and 2.92–3.16% ash. Morphological identification techniques revealed fourteen fungal species belonging to six fungal genera from which Aspergillus flavus was the leading contaminant. AFB1 analysis revealed that sixty-two percent samples were contaminated with AFB1. All the AFB1 positive samples contained AFB1 level more than 2 ppb and 12.9% samples contain AFB1 level more than 20 ppb, exceeded the maximum limit (ML) assigned by EU and USA (FDA & FAO) respectively. The results of the present studies reported that chickpea is a highly contaminated commodity in terms of fungi and AFB1 that’s why further investigations and monitoring are required to reduce the fungal and AFB1 contamination. These baseline data are an initial step in the effort to deal with this significant food safety issue.
Covert Neurological Symptoms Associated With Silent Infarcts From Midlife to Older Age: The Atherosclerosis Risk in Communities Study
Creators: name: Penman, A.
name: Windham, B. G.
name: Griswold, M. E.
name: Mosley, T. H.
name: Shibata, D.
name: Catellier, D. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Unrecognized or unreported stroke-like symptoms, called covert symptoms, occur in persons free of clinical stroke. Whether covert symptoms are associated with subclinical brain infarcts (SBI) is unknown. This study examined the association between covert stroke-like symptoms and SBI/stroke in persons with no history of stroke or TIA.
Mach-Type Soliton in the Novikov-Veselov Equation
Creators: name: Chang, Jen-Hsu
Publisher: name: arXiv
Year: 2014
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: Using the reality condition of the solutions, one constructs the Mach-type soliton of the Novikov-Veselov equation by the minor-summation formula of the Pfaffian. We study the evolution of the Mach-type soliton and find that the amplitude of the Mach stem wave is less than two times of the one of the incident wave. It is shown that the length of the Mach stem wave is linear with time. One discusses the relations with V -shape initial value wave for different critical values of Miles parameter.
A Challenging Solar Eruptive Event of 18 November 2003 and the Causes of the 20 November Geomagnetic Superstorm. IV. Unusual Magnetic Cloud and Overall Scenario
Creators: name: Grechnev, V. V.
name: Uralov, A. M.
name: Chertok, I. M.
name: Belov, A. V.
name: Filippov, B. P.
name: Slemzin, V. A.
name: Jackson, B. V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The geomagnetic superstorm of 20 November 2003 with Dst = -422 nT, one of the most intense in history, is not well understood. The superstorm was caused by a moderate solar eruptive event on 18 November, comprehensively studied in our preceding Papers I-III. The analysis has shown a number of unusual and extremely complex features, which presumably led to the formation of an isolated right-handed magnetic-field configuration. Here we analyze the interplanetary disturbance responsible for the 20 November superstorm, compare some of its properties with the extreme 28-29 October event, and reveal a compact size of the magnetic cloud (MC) and its disconnection from the Sun. Most likely, the MC had a spheromak configuration and expanded in a narrow angle of < 14 degree. A very strong magnetic field in the MC up to 56 nT was due to the unusually weak expansion of the disconnected spheromak in an enhanced-density environment constituted by the tails of the preceding ICMEs. Additional circumstances favoring the superstorm were (i) the exact impact of the spheromak on the Earth's magnetosphere and (ii) the almost exact southward orientation of the magnetic field, corresponding to the original orientation in its probable source region near the solar disk center.
description: 24 pages, 4 figures. For associated movie file, see http://ru.iszf.irk.ru/~grechnev/papers/2003-11-18_IV. Accepted for publication in Solar Physics. The final publication is available at Springer via http://dx.doi.org/10.1007/s11207-014-0596-5
Acute Stroke Imaging Research Roadmap II
Creators: name: Jovin, Tudor G.
name: Alexandrov, Andrei V.
name: Yoo, Albert J.
name: Fiehler, Jens
name: Wardlaw, Joanna M.
name: Lev, Michael H.
name: Alger, Jeffry R.
name: Bammer, Roland
name: Christensen, Søren
name: Copen, William A.
name: Haley, E. Clarke
name: Baron, Jean-Claude
name: Grotta, James C.
name: Derdeyn, Colin P.
name: Khatri, Pooja
name: Demchuk, Andrew M.
name: Albers, Gregory W.
name: Fiebach, Jochen B.
name: Luby, Marie
name: Liebeskind, David S.
name: Calamante, Fernando
name: Wu, Ona
name: Aviv, Richard I.
name: Houser, Gary
name: Wintermark, Max
name: Lees, Kennedy R.
name: Carpenter, Trevor C.
name: Broderick, Joseph P.
name: von Kummer, Rüdiger
name: Parsons, Mark W.
name: Muir, Keith W.
name: Campbell, Bruce C.V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: No abstract available.
A Metagrammatical Approach to Periphrasis in Gwadloupéyen
Creators: name: Schang, Emmanuel
Publisher: name: Quaderni di Linguistica e Studi Orientali
Year: 2018

description: In this paper, I show that verbal and nominal functional elements of Gwadloupéyen can be described in the Tree-Adjoining Grammar as pertaining to morphological periphrasis. This challenges the claim that Creoles have fully analytical morphology.
description: Quaderni di Linguistica e Studi Orientali, Vol 4 (2018)
A new X-ray nova MAXI J1910-057 (= Swift J1910.2-0546) and mass-accretion inflow
Creators: name: Nakahira, Satoshi
name: Negoro, Hitoshi
name: Shidatsu, Megumi
name: Ueda, Yoshihiro
name: Mihara, Tatehiro
name: Sugizaki, Mutsumi
name: Matsuoka, Masaru
name: Onodera, Takuya
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We report on a long-term monitoring of a newly discovered X-ray nova, MAXI J1910-057 (= Swift J1910.2-0546), by MAXI and Swift. The new X-ray transient was first detected on 2012 May 31 by MAXI Gas Slit Camera (GSC) and Swift Burst Alert Telescope (BAT) almost simultaneously. We analyzed X-ray and UV data for 270 days since the outburst onset taken by repeated MAXI scans and Swift pointing observations. The obtained X-ray light curve for the inital 90 days is roughly represented by a fast-rise and exponential-decay profile. However, it re-brightened on the ~110 days after the onset and finally went down below both GSC and BAT detec- tion limits on the 240 day. All the X-ray energy spectra are fitted well with a model consisting of a multi-color-disk blackbody and its Comptonized hard tail. During the soft-state periods, the inner-disk radius of the best-fit model were almost constant. If the radius represents the innermost stable circular orbit of a non-spinning black hole and the soft-to-hard transitions occur at 1-4% of the Eddington luminosity, the mass of the compact object is estimated to be > 2.9Mo and the distance to be > 1.70 kpc. The inner-disk radius became larger in the hard / hard-intermediate state. This suggests that the accretion disk would be truncated. We detected an excess of the UV flux over the disk blackbody component extrapolated from the X-ray data, which can be modelled as reprocessed emission irradiated by the inner disk. We also found that the UV light curve mostly traced the X-ray curve, but a short dipping event was observed in both the UV and the X-ray bands with a 3.5-day X-ray time lag. This can be interpreted as the radial inflow of accreting matter from the outer UV region to the inner X-ray region.
description: 11 pages, 5 figures, PASJ in print
General Locative Marking in Martinican Creole (Matinitjè): A Case Study in Grammatical Economy
Creators: name: Zribi-Hertz, Anne
name: Loïc, Jean-Louis
Publisher: name: Quaderni di Linguistica e Studi Orientali
Year: 2018

description: Th is article bears on General Locative Marking (GLM), as exemplifi ed in Martinican Creole (MQ): the surface homonymy of phrases denoting Goal, Source and Stative Location. With a few languages as comparative background, we explore in some detail the expression of stative location and directional predications in MQ, breaking down GLM into two independent homonymies – Place/Goal, and Goal/Source. The first homonymy is not a Creole innovation since it obtains in French and various West-African languages. The Goal/Source homonymy, an MQ innovation with respect to French, is attested in some West-African languages but also in Indian-Ocean Creoles (whose Non-European features are not West-African), and assumedly results from the general non-survival of French "de" in French-Based-Creole lexicons (Syea 2017), an expected development under general patterns of unguided L2-acquisition (Klein & Perdue 1997). On the other hand, the licensing of Goal and Source arguments by directional verbs in serial-verb constructions is likely to be of West-African origin. MQ thus appears as a good illustration of the hybrid nature of Creole grammars (Mufwene 2001, 2010; Aboh 2015), involving the recombination of European and Non-European features under general laws of language change and grammatical economy.
description: Quaderni di Linguistica e Studi Orientali, Vol 4 (2018)
MR Imaging of Oxygen Extraction and Neurovascular Coupling
Creators: name: An, H.
name: Chen, Y.
name: Vo, K. D.
name: Lin, W.
name: Powers, W. J.
name: Ford, A. L.
name: Lee, J.-M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Since the approval of tissue-type plasminogen activator (tPA) for the treatment of acute ischemic stroke by the Food and Drug Administration,1 the search for means to identify patients who may benefit from this treatment beyond the approved therapeutic window has been actively pursued. One of the most successful examples is the European Cooperative Acute Stroke Study III (ECASS III) trial,2,3 which demonstrated that efficacy of tPA treatment could be extended from the original 3 hours to 4.5 hours from onset. In addition, with an accumulating arsenal of mechanical clot retrieval devices, promising to achieve more effective reperfusion than intravenous-tPA,4–6 it is likely that the therapeutic windows for these retrieval devices will differ from that of intravenous-tPA. Different collateral flow patterns, comorbidities, and intrinsic tissue vulnerabilities among individual patients further complicate the use of a fixed therapeutic time-window for all patients and different treatments. Therefore, insights into brain tissue viability at the time of presentation may aid in the management of acute stroke. Toward this end, imaging approaches have been actively sought to provide a potential signature for tissue viability.7 Specifically, the diffusion/perfusion mismatch (DPM) concept has been widely advocated as a potential approach to depict the presence or absence of ischemic penumbra.8–10 The underlying hypothesis is that lesions defined by abnormal diffusion most likely reflect irreversible injury, whereas regions defined by abnormal perfusion represent critically hypoperfused tissue. The region of DPM with normal diffusion but abnormal perfusion is, in theory, the region at risk of evolving to infarction if reperfusion-promoting therapies are not administered. Although the overall hypothesis of DPM is straightforward and diffusion weighted images (DWI) and perfusion-weighted images (PWI) are readily available, the means by which DWI and PWI lesions are defined vary widely, leading to, potentially, …
Crystal-liquid interfacial free energy of hard spheres via a novel thermodynamic integration scheme
Creators: name: Benjamin, Ronald
name: Horbach, Jürgen
Publisher: name: arXiv
Year: 2014
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Chemical Physics (physics.chem-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The hard sphere crystal-liquid interfacial free energy, ($γ_{\rm cl}$), is determined from molecular dynamics simulations using a novel thermodynamic integration (TI) scheme. The advantage of this TI scheme compared to previous methods is to successfully circumvent hysteresis effects due to the movement of the crystal-liquid interface. This is accomplished by the use of extremely short-ranged and impenetrable Gaussian flat walls which prevent the drift of the interface while imposing a negligible free-energy penalty. We find that it is crucial to analyze finite-size effects in order to obtain reliable estimates of $γ_{\rm cl}$ in the thermodynamic limit.
description: 10 pages, 6 figures
Poststroke Outcomes Vary by Pathogenic Stroke Subtype in The Atherosclerosis Risk in Communities Study
Creators: name: Rosamond, W. D.
name: Sen, S.
name: Jones, S. B.
name: Lakshminarayan, K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: BACKGROUND AND PURPOSE: Early risk of recurrence and mortality after stroke differs by subtype, but less is known about long-term recurrence and hospital readmissions. These differences have economic implications and will affect long-term disability and stroke survivor quality of life. We examined recurrent stroke, all-cause hospital readmission, and mortality by index pathogenic subtype.

METHODS: We identified 987 Atherosclerosis Risk in Communities Study cohort participants with first-ever stroke and followed them for a median 5.3 years after first stroke. Outcomes were compared across index subtypes (infarction: thrombotic, cardioembolic, and lacunar; hemorrhagic: subarachnoid and intracerebral) using Kaplan-Meier analysis and Cox proportional hazards regression, adjusting for age, sex, and race.

RESULTS: There were 183 recurrent strokes among 147 participants, 3234 hospitalizations among 746 participants, and 529 deaths; only 14% of participants were event-free over follow-up. The majority of recurrent events were of the same subtype, except for lacunar infarcts, which were followed ≈3 quarters of the time by nonlacunar events. Adjusted mortality was higher for intracerebral hemorrhage (hazard ratio, 2.3; 95% confidence interval, 1.7-3.0) compared with thrombotic stroke and lower for lacunar infarcts. Lacunar infarcts had somewhat higher recurrence compared with thrombotic infarcts (hazard ratio, 1.3; 95% confidence interval, 0.9-1.9), but lower all-cause readmission (hazard ratio, 0.8; 95% confidence interval, 0.7-1.0). Readmission was 40% higher for cardioembolic stroke relative to thrombotic stroke (hazard ratio, 1.4; 95% confidence interval, 1.1-1.7).

CONCLUSIONS: Although the highest mortality was observed for intracerebral hemorrhage, there was significant burden of recurrent stroke and hospital readmissions for lacunar and cardioembolic strokes, respectively. There may be opportunities to reduce the relatively high rate of poststroke readmissions.
Three new compounds from Anoectochilus roxburghii (Wall.) Lindl
Creators: name: Bin, Yan-Lin
name: Liu, Shun-Zhi
name: Xie, Ting-Ting
name: Feng, Wen-Zheng
name: Li, Hao-Yang
name: Ye, Zi-Jia
name: Dong, Zhi-Hao
name: Qiu, Ying-Kun
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: In this study, three new compounds, roxburic acid A (1) and two flavone glycosides isorhamnetin-3-O-α-L-rhamnosyl-(1→6)-β-D-glucopyranose-(1→3)-β-D-glucopyranoside (2), and kaempferol-7-O-β-D-glucopyranosyl-(1→3)-β-D-glucopyranoside (3) were isolated from an ethanol extract of the fresh Anoectochilus roxburghii (Wall.) Lindl., together with 10 known compounds (4-13). The structures of these compounds were comprehensively characterized by HR-ESI-MS, 1H NMR, 13C NMR, and 2 D-NMR. The DPPH free radical scavenging activity of the isolated compounds was evaluated, and the results showed that kaempferol-7-O-β-D-glucopyranosyl- (1→3) -β-D-glucopyranoside (3) and rutin (11) has the potential antioxidant activity with IC50 values of 139 μg/mL and 22.5 μg/mL respectively.
Risk analysis of Trojan-horse attacks on practical quantum key distribution systems
Creators: name: Jain, Nitin
name: Stiller, Birgit
name: Khan, Imran
name: Makarov, Vadim
name: Marquardt, Christoph
name: Leuchs, Gerd
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: An eavesdropper Eve may probe a quantum key distribution (QKD) system by sending a bright pulse from the quantum channel into the system and analyzing the back-reflected pulses. Such Trojan-horse attacks can breach the security of the QKD system if appropriate safeguards are not installed or if they can be fooled by Eve. We present a risk analysis of such attacks based on extensive spectral measurements, such as transmittance, reflectivity, and detection sensitivity of some critical components used in typical QKD systems. Our results indicate the existence of wavelength regimes where the attacker gains considerable advantage as compared to launching an attack at 1550 nm. We also propose countermeasures to reduce the risk of such attacks.
description: 11 pages, 7 figures, and author biographies (closer to the published version)
Noise-immune cavity-enhanced optical frequency comb spectroscopy: A sensitive technique for high-resolution broadband molecular detection
Creators: name: Khodabakhsh, Amir
name: Johansson, Alexandra C.
name: Foltynowicz, Aleksandra
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Noise-immune cavity-enhanced optical frequency comb spectroscopy (NICE-OFCS) is a recently developed technique that utilizes phase modulation to obtain immunity to frequency-to-amplitude noise conversion by the cavity modes and yields high absorption sensitivity over a broad spectral range. We describe the principles of the technique and discuss possible comb-cavity matching solutions. We present a theoretical description of NICE-OFCS signals detected with a Fourier transform spectrometer (FTS), and validate the model by comparing it to experimental CO2 spectra around 1575 nm. Our system is based on an Er:fiber femtosecond laser locked to a cavity and phase-modulated at a frequency equal to a multiple of the cavity free spectral range (FSR). The NICE-OFCS signal is detected by a fast-scanning FTS equipped with a high-bandwidth commercial detector. We demonstrate a simple method of passive locking of the modulation frequency to the cavity FSR that significantly improves the long term stability of the system, allowing averaging times on the order of minutes. Using a cavity with a finesse of ~9000 we obtain absorption sensitivity of 6.4 x 10^{-11} cm^{-1} Hz^{-1/2} per spectral element, and concentration detection limit for CO2 of 450 ppb Hz^{-1/2}, determined by multiline fitting.
description: submitted to the FLAIR2014 special issue of Applied Physics B
Serum Fatty Acids and Incidence of Ischemic Stroke Among Postmenopausal Women
Creators: name: Yaemsiri, S.
name: Wasserthiel-Smoller, S.
name: Robinson, W. R.
name: Tinker, L. F.
name: He, K.
name: Sen, S.
name: Rosamond, W.
name: Evans, R. W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: While studies have linked types of fatty acids with coronary heart disease, data on individual fatty acids and risk of ischemic stroke are limited. We aimed to examine the associations between serum fatty acid concentrations and incidence of ischemic stroke and its subtypes.
Atrial Fibrillation and Cognitive Decline–The Role of Subclinical Cerebral Infarcts: The Atherosclerosis Risk in Communities Study
Creators: name: Mosley, Thomas
name: Agarwal, Sunil K.
name: Loehr, Laura
name: Lopez, Faye L.
name: Alonso, Alvaro
name: Chen, Lin Y.
name: Huxley, Rachel R.
name: Gottesman, Rebecca F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The mechanism underlying the association of atrial fibrillation (AF) with cognitive decline in stroke-free individuals is unclear. We examined the association of incident AF with cognitive decline in stroke-free individuals, stratified by subclinical cerebral infarcts (SCIs) on brain MRI scans.
Bott periodicity in the Hit Problem
Creators: name: Ault, Shaun V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 55S10

description: In this short note, we use Robert Bruner's $\mathcal{A}(1)$-resolution of $P = \mathbb{F}_2[t]$ to shed light on the Hit Problem. In particular, the reduced syzygies $P_n$ of $P$ occur as direct summands of $\widetilde{P}^{\otimes n}$, where $\widetilde{P}$ is the augmentation ideal of the map $P \to \mathbb{F}_2$. The complement of $P_n$ in $\widetilde{P}^{\otimes n}$ is free, and the modules $P_n$ exhibit a type of "Bott Periodicity" of period $4$: $P_{n+4} = Σ^8P_n$. These facts taken together allow one to analyze the module of indecomposables in $\widetilde{P}^{\otimes n}$, that is, to say something about the "$\mathcal{A}(1)$-hit Problem." Our study is essentially in two parts: First, we expound on the approach to the Hit Problem begun by William Singer, in which we compare images of Steenrod Squares to certain kernels of Squares. Using this approach, the author discovered a nontrivial element in bidegree $(5, 9)$ that is neither $\mathcal{A}(1)$-hit nor in $\mathrm{ker} Sq^1 + \mathrm{ker} Sq^3$. Such an element is extremely rare, but Bruner's result shows clearly why these elements exist and detects them in full generality. Second, we describe the graded $\mathbb{F}_2$-space of $\mathcal{A}(1)$-hit elements of $\widetilde{P}^{\otimes n}$ by determining its Hilbert series.
description: 10 pages
Predicting Stroke Through Genetic Risk Functions: The CHARGE Risk Score Project
Creators: name: Meigs, J. B.
name: Kathiresan, S.
name: Fontes, J. D.
name: Wieberdink, R. G.
name: Ibrahim-Verbaas, C. A.
name: Schmidt, H.
name: Amin, N.
name: Choi, S. H.
name: Dichgans, M.
name: Lahti, J.
name: Rosamond, W. D.
name: Folsom, A. R.
name: Malik, R.
name: Bis, J. C.
name: Heckbert, S. R.
name: Nalls, M.
name: Ehret, G. B.
name: Lumley, T.
name: O'Donnell, C. J.
name: Hofman, A.
name: Taylor, K. D.
name: Fox, C. S.
name: Dehghan, A.
name: Boerwinkle, E.
name: Rao, M.
name: Shahar, E.
name: Rice, K.
name: Rotter, J. I.
name: Gottesman, R. F.
name: Fornage, M.
name: Psaty, B. M.
name: Koudstaal, P. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Beyond the Framingham Stroke Risk Score (FSRS), prediction of future stroke may improve with a genetic risk score (GRS) based on Single nucleotide polymorphisms (SNPs) associated with stroke and its risk factors.
"correlation_matrix_of_ZJet_v1" of "Rapidity distributions in exclusive Z + jet and $\gamma$ + jet events in pp collisions at $\sqrt{s}$=7 TeV"
Creators: name: CMS Collaboration
Publisher: name: HEPData
Year: 2014

description: Link to correlation matrix for the Z boson
description: CERN-LHC. Rapidity distributions are presented for events containing either a Z boson or a photon with a single jet in proton-proton collisions produced at the CERN LHC. The data, collected with the CMS detector at sqrt(s) = 7 TeV, correspond to an integrated luminosity of 5.0 fb^-1. The individual rapidity distributions of the boson and the jet are consistent within 5% with expectations from perturbative QCD. However, QCD predictions for the sum and the difference in rapidities of the two final-state objects show discrepancies with CMS data. In particular, next-to-leading-order QCD calculations, and two common Monte Carlo event generators using different methods to match matrix-element partons with parton showers, appear inconsistent with the data as well as with each other.
Sickle Cell Trait and Incident Ischemic Stroke in the Atherosclerosis Risk in Communities Study
Creators: name: Gottesman, Rebecca F.
name: Kshirsagar, Abhijit V.
name: Key, Nigel S.
name: Caughey, Melissa C.
name: Derebail, Vimal K.
name: Grove, Megan L.
name: Loehr, Laura R.
name: Heiss, Gerardo
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Numerous case reports describe stroke in individuals with sickle cell trait (SCT) in the absence of traditional risk factors for cerebrovascular disease. To date, no prospective epidemiological studies have investigated this association.
Supernova remnant W49B and its environment
Creators: name: Zhu, H.
name: Tian, W. W.
name: Zuo, P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We study Gamma-ray supernova remnant W49B and its environment using recent radio and infrared data. {\it Spitzer} IRS low resolution data of W49B shows shocked excitation lines of H$_{2}$ (0,0) S(0)-S(7) from the SNR-molecular cloud interaction. The H$_2$ gas is composed of two components with temperature of $\sim$260 K and $\sim$1060 K respectively. Various spectral lines from atomic and ionic particles are detected towards W49B. We suggest the ionic phase has an electron density of $\sim$500 cm${}^{-3}$ and a temperature of $\sim$${10^4}$ K by the spectral line diagnoses. The mid- and far-infrared data from {\it MSX}, {\it Spitzer} and {\it Herschel} reveals a 151 $\pm$ 20 K hot dust component with a mass of 7.5 $\pm$ 6.6 $\times$ ${10}^{-4} {\Msol}$ and a 45 $\pm$ 4 K warm dust component with a mass of 6.4 $\pm$ 3.2 ${\Msol}$. The hot dust is likely from materials swept up by the shock of W49B. The warm dust may possibly originate from the evaporation of clouds interacting with W49B. We build the HI absorption spectra of W49B and nearby four {\HII} regions (W49A, G42.90+0.58, G42.43-0.26 and G43.19-0.53), and study the relation between W49B and the surrounding molecular clouds by employing the 2.12 $μ$m infrared and CO data. We therefore obtain a kinematic distance of $\sim$10 kpc for W49B and suggest that the remnant is likely associated with the CO cloud at about 40 km s$^{-1}$.
description: 11 pages, 13 figures, accepted for publication in ApJ
Social Network, Social Support, and Risk of Incident Stroke: Atherosclerosis Risk in Communities Study
Creators: name: Rose, Kathryn M.
name: Iso, Hiroyasu
name: Everson-Rose, Susan A.
name: Nagayoshi, Mako
name: Mosley, Thomas H.
name: Lutsey, Pamela L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Having a small social network and lack of social support have been associated with incident coronary heart disease, however epidemiologic evidence for incident stroke is limited. We assessed the longitudinal association of a small social network and lack of social support with risk of incident stroke, and evaluated whether the association was partly mediated by vital exhaustion and inflammation.
"correlation_matrix_of_PhotonJet_v1" of "Rapidity distributions in exclusive Z + jet and $\gamma$ + jet events in pp collisions at $\sqrt{s}$=7 TeV"
Creators: name: CMS Collaboration
Publisher: name: HEPData
Year: 2014

description: Link to correlation matrix for the photon
description: CERN-LHC. Rapidity distributions are presented for events containing either a Z boson or a photon with a single jet in proton-proton collisions produced at the CERN LHC. The data, collected with the CMS detector at sqrt(s) = 7 TeV, correspond to an integrated luminosity of 5.0 fb^-1. The individual rapidity distributions of the boson and the jet are consistent within 5% with expectations from perturbative QCD. However, QCD predictions for the sum and the difference in rapidities of the two final-state objects show discrepancies with CMS data. In particular, next-to-leading-order QCD calculations, and two common Monte Carlo event generators using different methods to match matrix-element partons with parton showers, appear inconsistent with the data as well as with each other.
D5.6 Updated API for HTM to allow integration into the Digital Twin Platform
Creators: name: Porkka, Janne
name: Piira, Kalevi
name: Nykänen, Esa
name: Nummelin, Olli
name: Oikarinen, Mika
Publisher: name: Zenodo
Year: 2023

description: This deliverable introduces briefly a new demand-based thermal comfort concept (HTM Control) and describes API for HTM service for integration to SPHERE Digital Twin ecosystem. First, background information is introduced for this new demand-based thermal comfort concept. Then, the four use cases are specified for HTM service including HTM dashboard online and three use cases for API queries (JSON) for data. Finally, we also tell the status of implementation and explain how HTM service is tested in one or more real pilot projects.
Phytochemical analysis, antioxidant, and anticholinesterase activities of ethanolic extracts from five ginger plants in Thailand
Creators: name: Pawin, Benjaporn
name: Suksathan, Ratchuporn
name: Puangpradab, Ratchadawan
name: Rachkeeree, Apinya
name: Kantadoung, Kuttiga
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: Five selected medicinal plants in the family Zingiberaceae, Alpinia nigra, Boesenbergia maxwellii, Etlingera araneosa, Meistera koenigii, and Wurfbainia biflora, were collected from Thailand. HPLC was used to determine the content of phenolic compounds in their ethanolic extracts. The total phenolic contents and the total flavonoid contents of M. koenigii were found to be higher than that of the others. The antioxidant activity of the extracts was assayed by two methods, namely ABTS and DPPH assays using HPTLC and a microplate spectrophotometer. Anticholinesterase activity was screened by the Ellman method against acetylcholinesterase, the chief enzyme of Alzheimer’s disease. The results showed mild acetylcholinesterase effects. The results indicated that these five ginger species, especially M. koenigii have the potential to be a good source of natural antioxidants and anticholinesterase agents that could be further applied in the pharmaceutical industry.
Linking Ly-alpha and Low-Ionization Transitions at Low Optical Depth
Creators: name: Jaskot, A. E.
name: Oey, M. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We suggest that low optical depth in the Lyman continuum (LyC) may relate the Ly-alpha emission, C II and Si II absorption, and C II* and Si II* emission seen in high-redshift galaxies. We base this analysis on Hubble Space Telescope COS spectra of four Green Pea (GP) galaxies, which may be analogs of z>2 Ly-alpha emitters (LAEs). In the two GPs with the strongest Ly-alpha emission, the Ly-alpha line profiles show reduced signs of resonant scattering. Instead, the Ly-alpha profiles resemble the H-alpha line profiles of evolved star ejecta, suggesting that the Ly-alpha emission originates from a low column density and similar outflow geometry. The weak C II absorption and presence of non-resonant C II* emission in these GPs support this interpretation and imply a low LyC optical depth along the line of sight. In two additional GPs, weak Ly-alpha emission and strong C II absorption suggest a higher optical depth. These two GPs differ in their Ly-alpha profile shapes and C II* emission strengths, however, indicating different inclinations of the outflows to our line of sight. With these four GPs as examples, we explain the observed trends linking Ly-alpha, C II, and C II* in stacked LAE spectra, in the context of optical depth and geometric effects. Specifically, in some galaxies with strong Ly-alpha emission, a low LyC optical depth may allow Ly-alpha to escape with reduced scattering. Furthermore, C II absorption, C II* emission, and Ly-alpha profile shape can reveal the optical depth, constrain the orientation of neutral outflows in LAEs, and identify candidate LyC emitters.
description: 7 pages, 4 figures, version accepted to ApJL
Stem Cells as an Emerging Paradigm in Stroke 3: Enhancing the Development of Clinical Trials
Creators: name: Case, C.
name: Aronowski, J.
name: Muir, K.
name: Hinson, J.
name: Willing, A.
name: Duncan, P.
name: Kondziolka, D.
name: Cramer, S. C.
name: Wechsler, L.
name: Chopp, M.
name: Modo, M.
name: Borlongan, C.
name: Kautz, S.
name: Cramer, S. C.
name: Snyder, E.
name: Boltze, J.
name: Vahidy, F.
name: Misra, V.
name: Fischkoff, S.
name: Steinberg, G.
name: Savitz, S. I.
name: Guzman, R.
name: Wechsler, L.
name: Carmichael, S. T.
name: Mays, R.
name: Hess, D. C.
name: Savitz, S. I.
name: Mitsias, P.
name: Huang, D.
name: Finklestein, S.
name: Chase, T.
name: Sinden, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Cell-based therapy continues to grow as a new field to explore investigational treatments for stroke. Leaders from academia and industry convened an inaugural meeting in 2007 with members of the National Institutes of Health and Food and Drug Administration (FDA) to generate consensus-based guidelines on the development of cell therapies for stroke, entitled “Stem Cells as an Emerging Paradigm in Stroke” (STEPS).1 These guidelines focused on preclinical studies that are considered important as part of a development program to support clinical testing of cell therapies. The STEPS meeting also provided recommendations on the conduct of early-stage clinical trials. Given the rapid advances in the field, a second meeting was held in 2009 to update and expand these guidelines, which were published as STEPS 2.2 In December 2011, investigators in academia, industry leaders, and members of the National Institutes of Health and FDA gathered at a third meeting, STEPS 3, to discuss emerging data on the mechanisms of action of cell therapy, the barriers to successful translation from animal models to patients, and the design of current clinical trials for acute and chronic stroke. Since the prior STEPS meeting, there are now several active cell therapy platforms for stroke and other neurological disorders, in stages that range from preclinical to clinical trials, and with sponsors that include industry, the National Institutes of Health, and the California Institute of Regenerative Medicine. As the field continues to progress and as pilot clinical studies are starting to show safety for some cell types, it has become necessary to formulate a new set of guidelines that address topics not covered in prior STEPS publications. Specifically, the current document reflects a compilation of recommendations that focus on more advanced stages of clinical testing, as well as the testing of cell therapies in a broader …
Strategic Planning to Reduce the Burden of Stroke Among Veterans: Using Simulation Modeling to Inform Decision Making
Creators: name: Bosworth, H. B.
name: Lich, K. H.
name: Bravata, D. M.
name: Cheng, E. M.
name: Williams, L. S.
name: Tian, Y.
name: Beadles, C. A.
name: Matchar, D. B.
name: Homer, J. B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Reducing the burden of stroke is a priority for the Veterans Affairs (VA) Health System, reflected by the creation of the VA Stroke Quality Enhancement Research Initiative (QUERI). To inform the initiative's strategic planning, we estimated the relative population-level impact and efficiency of distinct approaches to improving stroke care in the United States Veteran population to inform policy and practice.
The 0.1
Creators: name: Comparat, Johan
name: Richard, Johan
name: Kneib, Jean-Paul
name: Ilbert, Olivier
name: Gonzalez-Perez, V.
name: Tresse, Laurence
name: Zoubian, Julien
name: Arnouts, Stephane
name: Bacon, Roland
name: Brownstein, Joel R.
name: Baugh, Carlton
name: Delubac, Timothee
name: Ealet, Anne
name: Escoffier, Stephanie
name: Ge, Jian
name: Jullo, Eric
name: Lacey, Cedric
name: Ross, Nicholas P.
name: Schlegel, David
name: Schneider, Donald P.
name: Steele, Oliver
name: Tasca, Lidia
name: Yeche, Christophe
name: Lesser, Michael
name: Jiang, Zhaoji
name: Jing, Yipeng
name: Fan, Zhou
name: Fan, Xiaohui
name: Ma, Jun
name: Nie, Jundan
name: Wang, Jiali
name: Wu, Zhenyu
name: Zhang, Tianmeng
name: Zhou, Xu
name: Zhou, Zhimin
name: Zou, Hu
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present the [OII] luminosity function measured in the redshift range 0.1
description: 24 pages, 18 Figures, submitted