cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Veränderung der Hämoglobinkonzentration bei der Thrombozytenspende, festgestellt im Rahmen der Evaluierung einer nichtinvasiven Messmethode
Creators: name: Kühn, Alexander
Publisher: name: Otto von Guericke University Library, Magdeburg, Germany
Year: 2018
Subjects: subject: Hämoglobin
subject: Thrombozyt
subject: Blutspende
subject: 612.11

description: Der weltweite Bedarf an Blut und Blutprodukten ist nach wie vor ungebrochen. Um die freiwilligen Spender vor Komplikationen und Folgeerkrankungen zu schützen und die Qualität der Produkte sicherzustellen, sind die Blutspendedienste an zahlreiche Richtlinien und gesetzliche Auflagen gebunden. Zu den zentralen Voraussetzungen zählt dabei die Bestimmung der Hämoglobinkonzentration. Damit steht auch die Weiterentwicklung adäquater Messverfahren im Fokus von Wissenschaft und Industrie. Die Firma LMB verspricht mit dem Gerät NBM200 eine präzise, schnelle, kostengünstige und vor allem nichtinvasive Bestimmung der Hämoglobinkonzentration. Ziel dieser Arbeit war es, das nichtinvasive Messverfahren mit dem bisherigen Goldstandard, einer venösen Bestimmung, zu vergleichen. Dazu erfolgte die parallele Bestimmung der Hämoglobinkonzentration bei 97 potentiellen Spendern. Die statistische Auswertung ergab eine Standardabweichung von 0,78 mmol/l bei einem 95% Konfidenzintervall von -1,38 bis + 1,68 mmol/l. Diese statistische Abweichung erschien für eine zuverlässige Entscheidung über die Spendetauglichkeit nicht geeignet. Zudem erfolgte eine zweite nichtinvasive Bestimmung der Hämoglobinkonzentration nach stattgefundener Thrombozytapheresspende bei n=86 Spendern. Dabei wurde die Veränderung der Hämoglobinkonzentration während einer Thrombozytapheresspende untersucht. In der statistischen Auswertung fiel eine geringe (-1,5%), aber signifikante (p < 0,05) Abnahme der Hämoglobin-konzentration während der Spende auf. Trotz intensiver Betrachtung möglicher Ursachen konnte in der vorliegenden Arbeit kein statistisch signifikanter Einflussfaktor für die Abnahme der Hämoglobinkonzentration gefunden werden.
Effect of Strong Electron Correlation on the Efficiency of Photosynthetic Light Harvesting
Creators: name: Mazziotti, David A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Research into the efficiency of photosynthetic light harvesting has focused on two factors: (1) entanglement of chromophores, and (2) environmental noise. While chromophores are conjugated $π$-bonding molecules with strongly correlated electrons, previous models have treated this correlation implicitly without a mathematical variable to gauge correlation-enhanced efficiency. Here we generalize the single-electron/exciton models to a multi-electron/exciton model that explicitly shows the effects of enhanced electron correlation within chromophores on the efficiency of energy transfer. The model provides more detailed insight into the interplay of electron correlation within chromophores and electron entanglement between chromophores. Exploiting this interplay is assisting in the design of new energy-efficient materials, which are just beginning to emerge.
TMS induzierte virtuelle Läsionen im Frontal- und Parietallappen und deren Effekte auf selektive Aufmerksamkeit und Arbeitsgedächtnisspeicherung
Creators: name: Arnold, Tom
Publisher: name: Otto-von-Guericke-Universität Magdeburg
Year: 2018
Subjects: subject: Transkranielle magnetische Stimulation
subject: Visuelle Aufmerksamkeit
subject: Arbeitsgedächtnis
subject: 612.823312

description: Ziel dieser Studie ist es, mittels transkranieller Magnetstimulation (TMS) die Rolle bestimmter Hirnregionen bei der Filterung und Speicherung von Informationen im Arbeitsgedächtnis zu untersuchen. Die transkranielle Magnetstimulation (TMS) ist eine nicht-invasive Methode mit der definierte Areale des Gehirns erregt oder inhibiert werden können. Anders als bei bildgebenden Verfahren wie funktioneller Kernspintomographie, welche nur Aussagen über Korrelationen erlauben, ist es mit TMS möglich, Rückschlüsse über kausale Beziehungen zwischen Hirnstrukturen und kognitiven Funktionen zu ziehen. Im Besonderen interessiert hier die Arbeitsteilung zwischen frontalen und parietalen Hirnregionen bei der Selektion und Speicherung von Information im Arbeitsgedächtnis. Es wurde ein inhibitorisches Stimulationsprotokoll verwendet; die Stimulation erfolgte über dem dorsolateralen präfrontalen Kortex (DLPFC) und dem posterioren Parietalkortex (PPC). Das verwendete Arbeitsgedächtnis-Paradigma orientiert sich an der 2004 erschienen Studie von Edward K. Vogel & Maro G. Machizawa. Die Probanden entschieden ob präsentierte farbige Kreise in einer gezeigten Anordnung enthalten waren. In einem Teil der Durchgänge wurden zusätzlich Dreiecke gezeigt, die ignoriert werden sollten. Die Leistung beim Einspeichern und Filtern der Stimuli wurde vor und nach TMS-Stimulation gemessen, auf diese Weise soll die bislang nicht geklärte Arbeitsteilung zwischen frontalen und parietalen Hirnregionen bei der Informationsselektion und –speicherung weiter eruiert werden.
Nonlinear amplification techniques for inertial MEMS sensors
Creators: name: Sharma, Mrigank
Publisher: name: University of British Columbia
Year: 2014

description: Inertial sensors, specifically MEMS gyroscopes, suffer in performance with down scaling. Non linear amplification techniques, such as parametric resonance, can be employed in many resonant structures to alleviate this degradation in performance, improve sensitivity and Signal to Noise Ratio (SNR). In this thesis the application of parametric resonance amplification and damping to both modes of a vibratory gyroscope is carried out using specialized combs. Gap-varying combs, which are usually used for the sensing mode are known for producing electrostatic spring modulations. They are used in this thesis to achieve parametric modulation in sense mode, for increasing spectral selectivity and to reduce the equivalent input noise angular rate (from 0.0046 deg/s/√Hz to 0.0026 deg/s/√Hz , for a parametric gain of 5). Additionally, novel shaped combs were used for performing parametric modulation of the driven mode of a resonant gyroscope as well. Analytical modes for both types of parametric amplification are derived and experimentally verified. In order to study the effect of parametric modulation for large signal operation, the dynamic pull-in process is analyzed and modeled in inertial MEMS sensors. The dynamic analytical model is derived and experimentally verified for parametric amplification. The dependence of dynamic pull-in voltage amplitudes on the values of externally-induced accelerations (e.g. Coriolis accelerations in the case of vibratory gyroscopes) is experimentally. The measurements indicate that the dynamic pull-in voltages reduce from 100 V to 56 V for a designed and fabricated MEMS gyroscope (device A) and from 21.77 V to 17.3 V for a MEMS accelerometer (device B), for an equivalent input acceleration signal of 0.319 ms-2, when the structures are actuated at their resonance frequency. In order to further analyze the fundamental limitations of sensing at microscale, a separate noise analysis of MEMS resonant sensors is performed. The frequency-dependent damping theory is used to suggest new optimization methods for the design of MEMS vibratory gyroscopes.
Kraniosynostosen in Sachsen-Anhalt : Ergebnisse einer multizentrischen Untersuchung zu klinischen und epidemiologischen Aspekten
Creators: name: Neusel, Chantal
Publisher: name: Otto von Guericke University Library, Magdeburg, Germany
Year: 2018
Subjects: subject: Kraniostenose
subject: 618.9209751

description: Epidemiologische Studien mit Fokus auf der Prävalenzberechung und der pränatalen Diagnose von Kraniosynostosen wurden bisher in Deutschland nicht durchgeführt. Ziel dieser Studie war es daher im Rahmen einer populationsbezogenen Vollerfassung sowohl die Prävalenz und den Zeittrend von Kraniosynostosen auf dem Bevölkerungslevel des Bundeslandes Sachsen-Anhalt zu bestimmen als auch den Stellenwert der Pränataldiagnostik und den Zeitpunkt der Diagnosestellung zu analysieren. Die Datenanalyse ergab eine Prävalenz der Kraniosynostosen von 4,8 pro 10.000 Geborene und eine Lebendgeborenenprävalenz von 4,2 pro 10.000 Lebendgeburten. Der in der Literatur beschriebene ansteigende Trend konnte im Erfassungsgebiet im Zeitraum von 2000-2016 nicht durch statistische Signifikanz bestätigt werden. Die Kohortenanalyse mit n=91 zeigte, dass die Pränataldiagnostik trotz frühem durchschnittlichen Diagnosezeitpunkt keinen großen Stellenwert im klinischen Alltag einnimmt. In einer Fall-Kontroll-Analyse konnten das männliche Geschlecht, ein niedriges Geburtsgewicht und von der Norm abweichende Geburtslagen und -modi als Risikofaktoren gegenüber einer Kontrollgruppe (n=273) ermittelt werden. Ein neues Klassifikationssystem wurde entworfen, um die Patientenbetreuung zu optimieren.
Nanotechnology : the Next Industrial Revolution ?
Creators: name: Cappy, A.
name: Stievenard, D.
name: Vuillaume, D.
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2002
Subjects: ING-INF/01 Elettronica

description: The essence of nanotechnology is the ability to work at the molecular level, atom by atom, to create large structures with fundamentally new properties. Nanostructures offer a new paradigm for materials manufacture by submicron-scale self-organization and self-assembly to create entities from the “bottom up” rather than the “top down” method. Nanometer structures will foster a revolution not only in information technology hardware but also in advances healthcare, therapeutics, diagnostics, environment and energy.
Каталог тематических карт Арктики (Catalogue of the Thematic Maps of Arctic)
Creators: name: Lemenkova, Polina
Publisher: name: Zenodo
Year: 2019
Subjects: Map
Cartography
Catalog
Arctic
Mapping
Geography
Arctic Ocean
Bibliography
Environment

description: Catalogue of the Thematic Maps of Arctic available from Russ. and European sources: Atlases and separate maps
Interplay of non-linear elasticity and dislocation-induced superfluidity in solid Helium-4
Creators: name: Aleinikava, Darya
name: Kuklov, Anatoly
Publisher: name: arXiv
Year: 2011
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: The mechanism of the roughening induced partial depinning of gliding dislocations from Helium-3 impurities is proposed as an alternative to the standard "boiling off". We give a strong argument that Helium-3 remains bound to dislocations even at large temperatures due to very long equilibration times. A scenario leading to the similarity between elastic and superfluid responses of solid Helium-4 is also discussed. Its main ingredient is a strong suppression of the superfluidity along dislocation cores by dislocation kinks (D. Aleinikava, et. al., arXiv:0812.0983). These kinks, on one hand, determine the temperature and Helium-3 dependencies of the generalized shear modulus and, on the other hand, control the superfluid response. Several proposals for theoretical and experimental studies of solid Helium-4 are suggested.
description: final version accepted to the special JLTP issue on Supersolid, 16 pages, 6 figures: typos corrected, more explanations given
Image Analysis for Cosmology: Results from the GREAT10 Galaxy Challenge
Creators: name: Kitching, T. D.
name: Balan, S. T.
name: Bridle, S.
name: Cantale, N.
name: Courbin, F.
name: Eifler, T.
name: Gentile, M.
name: Gill, M. S. S.
name: Harmeling, S.
name: Heymans, C.
name: Hirsch, M.
name: Honscheid, K.
name: Kacprzak, T.
name: Kirkby, D.
name: Margala, D.
name: Massey, R. J.
name: Melchior, P.
name: Nurbaeva, G.
name: Patton, K.
name: Rhodes, J.
name: Rowe, B. T. P.
name: Taylor, A. N.
name: Tewes, M.
name: Viola, M.
name: Witherick, D.
name: Voigt, L.
name: Young, J.
name: Zuntz, J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In this paper we present results from the weak lensing shape measurement GRavitational lEnsing Accuracy Testing 2010 (GREAT10) Galaxy Challenge. This marks an order of magnitude step change in the level of scrutiny employed in weak lensing shape measurement analysis. We provide descriptions of each method tested and include 10 evaluation metrics over 24 simulation branches. GREAT10 was the first shape measurement challenge to include variable fields; both the shear field and the Point Spread Function (PSF) vary across the images in a realistic manner. The variable fields enable a variety of metrics that are inaccessible to constant shear simulations including a direct measure of the impact of shape measurement inaccuracies, and the impact of PSF size and ellipticity, on the shear power spectrum. To assess the impact of shape measurement bias for cosmic shear we present a general pseudo-Cl formalism, that propagates spatially varying systematics in cosmic shear through to power spectrum estimates. We also show how one-point estimators of bias can be extracted from variable shear simulations. The GREAT10 Galaxy Challenge received 95 submissions and saw a factor of 3 improvement in the accuracy achieved by shape measurement methods. The best methods achieve sub-percent average biases. We find a strong dependence in accuracy as a function of signal-to-noise, and indications of a weak dependence on galaxy type and size. Some requirements for the most ambitious cosmic shear experiments are met above a signal-to-noise ratio of 20. These results have the caveat that the simulated PSF was a ground-based PSF. Our results are a snapshot of the accuracy of current shape measurement methods and are a benchmark upon which improvement can continue. This provides a foundation for a better understanding of the strengths and limitations of shape measurement methods.
description: Accepted to MNRAS
Millimeter-Wave and Terahertz Devices Based on MEMS Concepts
Creators: name: Hartnagel, Hans L.
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2002
Subjects: ING-INF/01 Elettronica

description: The higher the frequency, the more significant are the losses. Therefore it is important even for semiconductors with relatively large energy gap to remove as much semiconducting material as possible. This leads to components and their circuits to be produced on thin semiconducting membranes where most of the substrate is etched away. It is then a relatively small step to employ mechanical motion of suitably structured devices for such properties as fine-tune phase shifting or power switching. Relevant technology details are presented. A number of active and passive components are described with their special operational behaviour.
A minimal BV action for Vasiliev's four-dimensional higher spin gravity
Creators: name: Boulanger, Nicolas
name: Colombo, Nicolo
name: Sundell, Per
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The action principle for Vasiliev's four-dimensional higher-spin gravity proposed recently by two of the authors, is converted into a minimal BV master action using the AKSZ procedure, which amounts to replacing the classical differential forms by vectorial superfields of fixed total degree given by the sum of form degree and ghost number. The nilpotency of the BRST operator is achieved by imposing boundary conditions and choosing appropriate gauge transitions between charts leading to a globally-defined formulation based on a principal bundle.
description: 39 pages, 1 figure. Additional comments in the conclusions
First demonstration of a GaInP/GaAs HBT YIG-tuned microwave oscillator
Creators: name: Prasad, S.J.
name: Haynes, C.
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 1994
Subjects: ING-INF/01 Elettronica

description: A YIG-tuned oscillator using GaInP/Ga As HBT as the active device is described. The oscillator can be tuned from 6 to 9GHz. The fT and fmax of the HBT was 42 and 33GHz respectively. At 7.8GHz, the phase noise of the oscillator was -85dBc/Hz at 10kHz offset from the carrier. These results compare very well with the phase noise data available for AlGaAs/GaAs HBT oscillators.
Theater als soziale Praxis - ostdeutsches Theater nach dem Systemumbruch
Creators: name: Jennicke, Skadi
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2009
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 832.92093552
subject: 792

description: Die wissenschaftliche Auseinandersetzung mit dem deutschsprachigen Theater richtet ihr Augenmerk sowohl in der Literaturwissenschaft als auch in der Theaterwissenschaft seit den neunziger Jahren vor-nehmlich auf ästhetische Phänomene. Die Wechselwirkung künstlerischer Praxis mit einem konkreten kulturellen und sozialen Kontext wird dabei in der Regel vernachlässigt. Kunst gilt als autonomes Feld mit eigenen Gesetzmäßigkeiten, deren Selbstreflexion inzwischen zum Kanon künstlerischer Produk-tion gehört, um sich dieser Autonomie stets aufs Neue zu versichern. Die vorliegende Studie untersucht ostdeutsches Theater unter der ausgewählten Perspektive des Sy-stemumbruchs. Sie geht dabei sowohl von der Autonomie des künstlerischen Felds im Sinne Pierre Bourdieus aus, berücksichtigt aber auch den indirekten Einfluss feldexterner Effekte auf die künstleri-sche Produktion, die Bourdieu in seine Theorie sozialer Felder integriert. Kunst unterliegt demnach nicht ausschließlich der Dynamik ihrer Eigengesetzlichkeit, sondern konstituiert sich in indirekter Wechselwirkung mit ihrem sozialen Umfeld
Families index for Boutet de Monvel operators
Creators: name: Melo, Severino
name: Schrohe, Elmar
name: Schick, Thomas
Publisher: name: arXiv
Year: 2012
Subjects: subject: K-Theory and Homology (math.KT)
subject: Analysis of PDEs (math.AP)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 19K56, 46L80, 58J32

description: We define the analytical and the topological indices for continuous families of operators in the C*-closure of the Boutet de Monvel algebra. Using techniques of C*-algebra K-theory and the Atiyah-Singer theorem for families of elliptic operators on a closed manifold, we prove that these two indices coincide.
description: to appear in M\"unster Journal of Mathematics. v2: stylistic changes for M\"unster Journal of Mathematics; 14 pages
Development of a molecular reporter for cell-specific visualization of jasmonates
Creators: name: Li, Yulong
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2018
Subjects: subject: 572

description: Pflanzen als ortsgebundene Organismen sind ständig abiotischen und biotischen Stressfaktoren ausgesetzt. Die Anpassung an diese Faktoren wird i.d.R. durch die Funktion von Phytohormonen gewährleistet, die niedermolekulare Signalmoleküle sind. Unter diesen Hormonen sind auch die Jasmonsäure (JA) und ihre Derivate, deren Zell- und Gewebe-spezifische Detektion aufgrund ihrer geringen Gehalte in pflanzlichen Zellen sehr schwierig ist. Diese Arbeit hatte zum Ziel, neue, nicht-invasive Detektionsmethoden für Jasmonate zu entwickeln und zu nutzen. Die angestrebte Methode sollte auf der Entstehung eines Fluoreszenzsignals in lebenden Zellen beruhen und spezifisch durch JA induzierbar sein. Die damit mögliche Lebendzell-Detektion von aktiver JA soll dazu beitragen, die zell-spezifische Funktion von JA in biotischen Interaktionen, aber auch in der Entwicklung von Pflanzen aufzuklären. Zusammenfassend stellen alle drei hier entwickelten Ansätze Möglichkeiten zum Zell- und Gewebe-spezifischen Nachweis von JA dar, wobei die Systeme, die auf der CSY4-vermittelten Abbau von RNA und den synthetischen JA-responsiven Promotoren beruhen, das größte Entwicklungspotential besitzen. Für alle der Methoden sind jedoch weitere Optimierungen notwendig.
description: As sessile organisms, plants are constantly exposed to biotic and abiotic environmental factors. Phytohormones such as jasmonic acid (JA) and its derivatives, which are low molecular weight signal molecules, control the adaptation in plants to specific conditions. Cell- and tissue-specific detection of jasmonates is still quite difficult due to their low levels within plant cells or tissues. This study aims to develop and to use a new non-invasive detection system for active jasmonates. The envisaged system should be based on the rise of fluorescent proteins in living cells appearing after specific induction by jasmonates. Such a monitoring of JA will allow getting insights to the cell specific functions of JA in biotic interactions and developmental processes. Three approaches to develop a non-invasive system for the detection of JA were followed in this study. In conclusion, three systems were developed in this study. The Csy4-mediated degradation of mRNA of reporter gene in combination with JA-mediated degradation of JAZ1-Csy4 fusion protein and the use of JAREs combined with TALE seem to be usable methods to detect JA on cell specific level. All the systems should be optimized in further.
Measurement of the strong coupling alpha_S from the three-jet rate in e+e- - annihilation using JADE data
Creators: name: Schieck, Jochen
name: Bethke, Siegfried
name: Kluth, Stefan
name: Pahl, Christoph
name: Trocsanyi, Zoltan
name: Collaboration, the JADE
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present a measurement of the strong coupling alpha_S using the three-jet rate measured with the Durham algorithm in e+e- -annihilation using data of the JADE experiment at centre-of-mass energies between 14 and 44 GeV. Recent theoretical improvements provide predictions of the three-jet rate in e+e- -annihilation at next-to-next-to-leading order. In this paper a measurement of the three-jet rate is used to determine the strong coupling alpha_s from a comparison to next-to-next-to-leading order predictions matched with next-to-leading logarithmic approximations and yields a value for the strong coupling alpha_S(MZ) = 0.1199+- 0.0010 (stat.) +- 0.0021 (exp.) +- 0.0054 (had.) +- 0.0007 (theo.) consistent with the world average.
description: 27 pages, 8 figures
Ultra broad band monolithically integrated HBT mixer
Creators: name: Plouchart, J.O.
name: Riet, M.
name: Wang, H.
name: Wawrzynkowski, E.
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 1994
Subjects: ING-INF/01 Elettronica

description: A monolithically integrated HBT mixer has been designed, fabricated and measured. This mixer is based on a Gilbert cell [1] for ultra broad band application. Positive conversion gain up to 18.5 GHz has been measured. To authors' knowledge this is the first monolithically integrated HBT mixer reported with such high operating frequency.
Search for anomalous Wtb couplings in single top quark production in ppbar collisions at sqrt(s) = 1.96 TeV
Creators: name: D0 Collaboration
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present new direct constraints on a general $Wtb$ interaction using data corresponding to an integrated luminosity of 5.4 fb$^{-1}$ collected by the D0 detector at the Tevatron $p\bar{p}$ collider. The standard model provides a purely left-handed vector coupling at the $Wtb$ vertex, while the most general, lowest dimension Lagrangian allows right-handed vector and left- or right-handed tensor couplings as well. We obtain precise limits on these anomalous couplings by comparing the data to the expectations from different assumptions on the $Wtb$ coupling.
description: Submitted to Phys. Lett. B
CONVERSACIONES INTERNACIONALES. Estereotipos de género en Internet
Creators: name: García-Holgado, A.
Publisher: name: Zenodo
Year: 2019
Subjects: WYRED; H2020; Digital Society; Youth; International conversations; Gender stereotypes

description: Presentación en la Facultad de Educación de la Universidad de Salamanca de las conversaciones internacionales sobre estereotipos de género en Internet, que se llevarán a cabo en la plataforma WYRED entre el 25 de febrero y el 10 de marzo de 2019.
Beeinflussung kardialer Gap Junctions durch Angiotensin II
Creators: name: Noack, Berit Marianne
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2008
Subjects: subject: Hochschulschrift
subject: Online-Publikation
subject: Zsfassung in engl. Sprache
subject: 616.1

description: Angiotensin II spielt eine Rolle in der Pathophysiologie von Herzerkrankungen. Die Regulation interzellulärer Kommunikation über Gap Junctions beeinflusst möglicherweise die Funktion des Herzens unter ( patho) physiologischen Bedingungen. Wir untersuchten die Effekte von Angiotensin II auf Connexin 43 (Cx43) und Connexin 40 (Cx40) in kultivierten neonatalen Rattenkardiomyozyten sowie die Rolle von Mitogen-aktivierten Proteinkinasen in der Angiotensin-II vermittelten Signaltransduction. Kultivierte neonatale Rattenkardiomyozyten wurden über 24 Stunden mit Angiotensin-II in Konzentrationen zwischen 10 und 1000 nM inkubiert. Die Connexin 43-Expression und Phosphorylierung nahm mit zunehmenden Angiotensin-II Konzentrationen zu. Die hervorgerufenen Effekte waren durch Zusatz des AT1-Rezeptorantagonisten Losartan vollständig blockierbar. Im Gegesatz dazu war die Expression und Phosphorylierung von Connexin 40 durch Angiotensin-II nicht zu beeinflussen. Diese beiden connexin wurden differentiell reguliert. Angiotensin-II erhöhte die Gap Junction leitfähigkeit, gemessen mittels Double-cell-voltage-clamp-Verfahren. Durch Inhibierung verschiedener MAP-Kinasen konnte eine Involvierung der ERK, sowie der p38 Kinase in der Signalkette nachgewiesen werden. Die Stimulierung von ERK und p38 durch Angiotensin-II via AT1-Rezeptor scheint demnach an der Regulation kardialer Gap Junctions unter (patho) physiologischen Bedingungen beteiligt zu sein.
description: Angiotensin-II (AT-II) participates in the pathophysiology of cardiovascular diseases. Regulation of gap junctional intercellular communication may influence heart function and its response to cardiac injury. We examined the effects of Angiotensin-II on connexin43 (Cx43) and connexin40 (Cx40) in cultured neonatal rat ventricular cardiomyocytes and the role of mitogen-activated protein kinase signaling in the Angiotensin-II-induced responses. Cultured neonatal rat ventricular cardiomyocytes were incubated for 24 h with Angiotensin-II at concentrations ranging from 10 to 1000 nM. Cx43 expression and phosphorylation increased with increasing concentrations ofAngiotensin-II. Angiotensin-II-induced Cx43 induction could be completely inhibited by the AT1 receptor antagonist losartan. In contrast to Cx43, Cx40 expression did not change in AT-II-treated cultured neonatal rat ventricular cardiomyocytes . Thus, these two connexins were differentially regulated. Angiotensin-II increased the gap junctional conductance between the cardiomyocytes in culture as measured using a dual-cell voltage clamp. Mitogen-activated protein kinase inhibition revealed that both ERK and p38 signal pathways were involved in the regulation of Cx43 by Angiotensin-II. Thus, stimulation of the ERK and p38 signal pathways via AT1 receptors may partcipate in the regulation of cardiac gap junctions under (patho)physiological conditions.
Topologies and design methods for folding kinetic structures : expanding the architectural paradigm
Creators: name: Wierzbicki, Madalina Nicoleta
Publisher: name: University of British Columbia
Year: 2014

description: Built environments are the most prominent and important part of our material culture. Although they are vital for accommodating the exponentially growing and increasingly urbanized population under the challenging conditions of severe climatic changes and destabilized global societies, researchers note that the methods of both their design and construction need to be significantly improved. The construction industry is the largest source of waste and remains inefficient, while the architectural profession is being challenged by digital technologies, conflicting paradigms, and adverse market realities. What then are the obstacles in improving buildings? Is it the lack of viable ideas? Or, is it the social reluctance to accept novel ideas? How can architects be the socially relevant force contributing viable concepts? This thesis builds upon the current theories asserting the importance of human behavior and intentionality for understanding built environments, thus considering the complexity of both the technical and cultural circumstances. It establishes that although architecture is usually considered as a solid and invariable static form, it never has been a static shell merely delimiting discrete spaces. Through all times, buildings comprised both fixed structures and adjustable devices, which were the interactive interfaces between the static structures and the transiency of human action. This study focuses on rigidly foldable kinetic structures as they exemplify the potential advantages and challenges of novel architecture; and they are a logical expansion of the traditional adjustable architectural elements. For decades, theorists expected kinetic architecture to address the shortcomings of the traditional buildings. However, solving folding kinetic geometries is difficult and is hindered by the unintuitive nature of the current digital tools. Furthermore, kinetic environments challenge the traditional expectations of occupants. In response, the present thesis investigates the evolving, influenced by digital technologies, paradigms of public spaces, and human reasoningdriven design tools, while incorporating such human-centric considerations as social dynamics, history, and culture into the engineering and architectural design methods for built environments. It is concluded that architecture, its design and construction are primarily a social endeavor. Therefore understanding the cognitive barriers of design tools and negotiating the social expectations are essential when advancing new technologies for architecture.
BEC-BCS Crossover with Feshbach Resonance for a Three-Hyperfine-Species Model
Creators: name: Zhu, Guojun
name: Leggett, Anthony J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We consider the behavior of an ultracold Fermi gas across a narrow Feshbach resonance, where the occupation of the closed channel may not be negligible. While the corrections to the single-channel formulae associated with the nonzero chemical potential and with particle conservation have been considered in the existing literature, there is a further effect, namely the "inter-channel Pauli exclusion principle" associated with the fact that a single hyperfine species may be common to the two channels. We focus on this effect and show that, as intuitively expected, the resulting corrections are of order $E_F/η$, where $E_F$ is the Fermi energy of the gas in the absence of interactions and $η$ is the Zeeman energy difference between the two channels. We also consider the related corrections to the fermionic excitation spectrum, and briefly discuss the collective modes of the system.
A novel voltage controlled directional coupler using a wide FET structure
Creators: name: Cryan, M.
name: Shepherd, P.R.
name: Pennock, S.R.
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 1994
Subjects: ING-INF/01 Elettronica

description: A wide FET is considered as a voltage controlled directional coupler. A model for the device has been developed taking into account the distributed nature of the device. The six port measured and modelled S-parameters are shown to 20GHz. The results show large variation in coupling between source and drain.
Effective slip boundary conditions for arbitrary one-dimensional surfaces
Creators: name: Asmolov, Evgeny S.
name: Vinogradova, Olga I.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: In many applications it is advantageous to construct effective slip boundary conditions, which could fully characterize flow over patterned surfaces. Here we focus on laminar shear flows over smooth anisotropic surfaces with arbitrary scalar slip $b(y)$, varying in only one direction. We derive general expressions for eigenvalues of the effective slip-length tensor, and show that the transverse component is equal to a half of the longitudinal one with twice larger local slip, $2b(y)$. A remarkable corollary of this relation is that the flow along any direction of the 1D surface can be easily determined, once the longitudinal component of the effective slip tensor is found from the known spatially nonuniform scalar slip.
description: 10 pages, 2 figures, submitted to J. Fluid Mech
Vicious accelerating walkers
Creators: name: Xu, S. -L. -Y.
name: Schwarz, J. M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: A vicious walker system consists of N random walkers on a line with any two walkers annihilating each other upon meeting. We study a system of N vicious accelerating walkers with the velocity undergoing Gaussian fluctuations, as opposed to the position. We numerically compute the survival probability exponent, α, for this system, which characterizes the probability for any two walkers not to meet. For example, for N = 3, α = 0.71 \pm 0.01. Based on our numerical data, we conjecture that 1/8N(N - 1) is an upper bound on α. We also numerically study N vicious Levy flights and find, for instance, for N = 3 and a Levy index μ = 1 that α = 1.31 \pm 0.03. Vicious accelerating walkers relate to no-crossing configurations of semiflexible polymer brushes and may prove relevant for a non-Markovian extension of Dyson's Brownian motion model.
description: 7.5 pages, 5 figures
The Ricci flow of asymptotically hyperbolic mass and applications
Creators: name: Balehowsky, T.
name: Woolgar, E.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Differential Geometry (math.DG)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We consider the evolution of the asymptotically hyperbolic mass under the curvature-normalized Ricci flow of asymptotically hyperbolic, conformally compactifiable manifolds. In contrast to asymptotically flat manifolds, for which ADM mass is constant during Ricci flow, we show that the mass of an asymptotically hyperbolic manifold of dimension n>2 decays smoothly to zero exponentially in the flow time. From this, we obtain a no-breathers theorem and a Ricci flow based, modified proof of the scalar curvature rigidity of zero-mass asymptotically hyperbolic manifolds. We argue that the nonconstant time evolution of the asymptotically hyperbolic mass is natural in light of a conjecture of Horowitz and Myers, and is a test of that conjecture. Finally, we use a simple parabolic scaling argument to produce a heuristic "derivation" of the constancy of ADM mass under asymptotically flat Ricci flow, starting from our decay formula for the asymptotically hyperbolic mass under the curvature-normalized flow.
description: Revised in accord with referee comments, typos and minor errors corrected, Appendix B added, footnotes in-lined; version accepted for publication
Improvement of microwave planar active filters with MMIC technology
Creators: name: Billonnet, L.
name: Brucher, A.
name: Cenac, C.
name: Delmond, M.
name: Meunier, Ph.
name: Jarry, B.
name: Guillon, P.
name: Sussman-Fort, S.E.
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 1994
Subjects: ING-INF/01 Elettronica

description: In this paper, new ranges of GaAs MMIC circuit applications at microwaves are presented with the development of original planar active filters in this technology. The first step is to improve intrinsic performances of planar microstrip resonators with the help of MMIC amplifier or negative resistance chips [1]. Finally, a novel active recursive structure is also demonstrated as an MMIC.
Die chirurgische Therapie des Hydrozephalus occlusus mittels endoskopischer Ventrikulozisternostomie - eine postoperative Studie
Creators: name: Enke, Steffen
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2007
Subjects: subject: Elektronische Publikation
subject: Hochschulschrift
subject: Online-Publikation
subject: Zsfassung in engl. Sprache
subject: 616.8

description: Die Behandlung des Hydrozephalus occlusus durch eine endoskopische Ventrikulozisternostomie stellt heute bei diesem Krankheitsbild die Therapie der Wahl dar. Für die Beurteilung des operativen Erfolges werden in der Literatur unterschiedlichste Aussagen getroffen. Die Kombination radiologischer und neuropsychologischer Untersuchungen bietet dabei ein hilfreiches Instrument zur Abschätzung dieser Ergebnisse. Die postoperative Rückbildung des Ventrikelsystems stellt sich erwartungsgemäß langsam dar, wobei signifikante Unterschiede zwischen akutem und chronischen Verlauf festgestellt werden können. In den Korrelationsanalysen zeigen sich zahlreiche Zusammenhänge zwischen den Resultaten der neuroradiologischen und der neuropsychologischen Untersuchungen. Im Vergleich mit der Literatur zeigen unser Patienten bessere neuropsychologische Ergebnisse als in vorangegangenen Studien nach konventioneller Hydrozephalustherapie.
description: Actually the treatment of hydrocephalus occlusus by an endoscopic ventriculocisternostomy is the preferred therapy at this clinical picture. To evaluate the operative success different statements are made in the literature. The combination of radiological and neuropsychological examination is a helpful instrument to evaluate these results. As expected the postoperative involution of the ventricular system occurs slowly whereby significant differences between acute and chronic courses are identifiable. In the analysis of results multiple correlations between the results of neuroradiological and neuropsychological examinations are recognizable. In comparison with the literature our patients showed much better neuropsychological results as in earlier studies with the conventional hydrocephalus therapy.
Ka-band coaxial and waveguide wide temperature range compensated low noise amplifiers
Creators: name: Pardini, R.
name: Miceli, A.
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 1994
Subjects: ING-INF/01 Elettronica

description: This  paper describes  the  design and manufacturing steps   of   two   different   Ka-band  microstrip   six stages    low   noise   amplifier   configurations, operating    over    the     temperature        range    of -4O/=125 °C. The    preliminary    performances    of    these    two components,in  the  Bandwidth  of  400MHz  centered at 35GHz,   are:   Noise   Figure   less  than   3.8dB  at   25 °C temperature   with   a   2.9   dB   NF   first   stage   and   a dual   temperature  compensation  network. Gain  is   in  excess  of   20dB  and   In/Out  VSWR  better than  1.5:1. Two different prototypes (i.e. waveguide WR28 and coaxial K-connector) are discussed.
Solving the Simplest Theory of Quantum Gravity
Creators: name: Dubovsky, Sergei
name: Flauger, Raphael
name: Gorbenko, Victor
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We solve what is quite likely the simplest model of quantum gravity, the worldsheet theory of an infinitely long, free bosonic string in Minkowski space. Contrary to naive expectations, this theory is non-trivial. We illustrate this by constructing its exact factorizable S-matrix. Despite its simplicity, the theory exhibits many of the salient features expected from more mature quantum gravity models, including the absence of local off-shell observables, a minimal length, a maximum achievable (Hagedorn) temperature, as well as (integrable relatives of) black holes. All these properties follow from the exact S-matrix. We show that the complete finite volume spectrum can be reconstructed analytically from this S-matrix with the help of the thermodynamic Bethe Ansatz. We argue that considered as a UV complete relativistic two-dimensional quantum field theory the model exhibits a new type of renormalization group flow behavior, "asymptotic fragility". Asymptotically fragile flows do not originate from a UV fixed point.
description: 32+4 pages, 1 figure, v2: typos fixed, published version
The "EMBRACE" (“Empowering Medical students’ skills in BReaking bAd news with Compassion and Empathy”) Module
Creators: name: Surapaneni, Krishna Mohan
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 390110
subject: Medicine, nursing and health curriculum and pedagogy
classificationCode: 390107
subject: Humanities and social sciences curriculum and pedagogy (excl. economics, business and management)

description: The "EMBRACE" (“Empowering Medical students’ skills in BReaking bAd news with Compassion and Empathy”) module is meticulously designed to empower undergraduate medical students in delivering bad news with compassion and empathy. The module is built on the essential communication skills competencies and well-defined learning outcomes, establishing a robust foundation for knowledge and skill acquisition. With a keen emphasis on effective communication and the nuanced challenges of delivering distressing news to patients, the module integrates evidence-based practices, notably incorporating the widely recognized 6-step "SPIKES" approach.The SPIKES framework, encompassing Setting, Perception, Invitation, Knowledge, Emotions, and Strategy, serves as a guiding structure, leading students through the intricate process of communicating sensitive information with a heightened sense of sensitivity and empathy. Each step within the SPIKES model is explained hence providing students with a comprehensive understanding of its importance and relevance. Additionally, a detailed step-by-step procedure is outlined, facilitating a clear and practical demonstration of each component.To further enhance comprehension and application, the module incorporates three sample conversations, offering tangible examples of how each step should be effectively executed in real-world scenarios. Complementing this, the module features 10 diverse case scenarios for self-assessment, allowing students to actively practice and refine their skills in breaking bad news while adhering to the 6-step SPIKES model.Acknowledging the importance of continued learning, the module extends beyond its core content by providing links to additional reading materials. This supplemental resource empowers students to delve deeper into the subject matter, fostering a culture of ongoing self-improvement.
A Density Independent Formulation of Smoothed Particle Hydrodynamics
Creators: name: Saitoh, Takayuki R.
name: Makino, Junichiro
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The standard formulation of the smoothed particle hydrodynamics (SPH) assumes that the local density distribution is differentiable. This assumption is used to derive the spatial derivatives of other quantities. However, this assumption breaks down at the contact discontinuity. At the contact discontinuity, the density of the low-density side is overestimated while that of the high-density side is underestimated. As a result, the pressure of the low (high) density side is over (under) estimated. Thus, unphysical repulsive force appears at the contact discontinuity, resulting in the effective surface tension. This tension suppresses fluid instabilities. In this paper, we present a new formulation of SPH, which does not require the differentiability of density. Instead of the mass density, we adopt the internal energy density (pressure), and its arbitrary function, which are smoothed quantities at the contact discontinuity, as the volume element used for the kernel integration. We call this new formulation density independent SPH (DISPH). It handles the contact discontinuity without numerical problems. The results of standard tests such as the shock tube, Kelvin-Helmholtz and Rayleigh-Taylor instabilities, point like explosion, and blob tests are all very favorable to DISPH. We conclude that DISPH solved most of known difficulties of the standard SPH, without introducing additional numerical diffusion or breaking the exact force symmetry or energy conservation. Our new SPH includes the formulation proposed by Ritchie & Thomas (2001) as a special case. Our formulation can be extended to handle a non-ideal gas easily.
description: 24 pages, 21 figures. Movies and high resolution figures are available at http://v1.jmlab.jp/~saitoh/sph/index.html
Thermodynamics of Classical Systems on Noncommutative Phase Space
Creators: name: Najafizadeh, Mojtaba
name: Saadat, Mehdi
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the formulation of statistical mechanics on noncommutative classical phase space, and construct the corresponding canonical ensemble theory. For illustration, some basic and important examples are considered in the framework of noncommutative statistical mechanics: such as the ideal gas, the extreme relativistic gas, and the 3-dimensional harmonic oscillator.
description: 11 pages, no figure
Wide-band GaAs MMIC low-pass filters
Creators: name: Boulouard, Andre
name: Le Rouzic, Michel
name: Castelletto, Jean Paul
name: Legaud, Pierre
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 1994
Subjects: ING-INF/01 Elettronica

description: Very small, Wide-band and low loss GaAs MMIC Bessel-Thomson, Gaussian and dissipative low-pass filters are proposed as low signal distortion filtering elements suitable for inclusion into high-speed fiber optic receivers. Five-element 2 5, 5 and 10 Gb/s filters using lumped reactive elements have been designed and fabricated using a standard MMIC foundry process.
Effect of correlations on network controllability
Creators: name: Pósfai, Márton
name: Liu, Yang-Yu
name: Slotine, Jean-Jacques
name: Barabási, Albert-László
Publisher: name: arXiv
Year: 2012
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Social and Information Networks (cs.SI)
subject: Systems and Control (eess.SY)
subject: Optimization and Control (math.OC)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Mathematics

description: A dynamical system is controllable if by imposing appropriate external signals on a subset of its nodes, it can be driven from any initial state to any desired state in finite time. Here we study the impact of various network characteristics on the minimal number of driver nodes required to control a network. We find that clustering and modularity have no discernible impact, but the symmetries of the underlying matching problem can produce linear, quadratic or no dependence on degree correlation coefficients, depending on the nature of the underlying correlations. The results are supported by numerical simulations and help narrow the observed gap between the predicted and the observed number of driver nodes in real networks.
Multi-Dimensional Radiative Transfer Calculations for Asymmetric Stripped-Envelope Supernovae
Creators: name: Maunder, Thomas Liam
Publisher: name: Monash University
Year: 2025
Subjects: classificationCode: 510106
subject: High energy astrophysics and galactic cosmic rays

description: This thesis presents observable signatures from simulations of the explosive death of massive stars. It tests the validity of state-of-the-art explosion models, making comparisons to observations of real supernova events.