cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Nuclear isotope thermometry
Creators: name: Souza, S. R.
name: Tan, W. P.
name: Donangelo, R.
name: Gelbke, C. K.
name: Lynch, W. G.
name: Tsang, M. B.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We discuss different aspects which could influence temperatures deduced from experimental isotopic yields in the multifragmentation process. It is shown that fluctuations due to the finite size of the system and distortions due to the decay of hot primary fragments conspire to blur the temperature determination in multifragmentation reactions. These facts suggest that caloric curves obtained through isotope thermometers, which were taken as evidence for a first-order phase transition in nuclear matter, should be investigated very carefully.
description: 9 pages, 7 figures
Additional file 1: of Prenatal plasma concentrations of Perfluoroalkyl and polyfluoroalkyl substances and neuropsychological development in children at four years of age
Creators: name: Niu, Jinbo
name: Liang, Hong
name: Tian, Youping
name: Yuan, Wei
name: Xiao, Hong
name: Hu, Hui
name: Sun, Xiaowei
name: Song, Xiuxia
name: Wen, Sheng
name: Yang, Li
name: Ren, Yanfeng
name: Miao, Maohua
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Table S1. The rates of potential developmental problem assessed at 4 years of age by the Age and Stage Questionnaire (ASQ). Table S2. Maternal PFASs concentrations (ng/mL) at 12â 16 gestational weeks stratified by child sex. Table S3. P-values of interaction item (PFASs*child sex) in the associations between maternal PFASs concentrations and childâ s neurobehavioral problems assessed by ASQ at 4 years of age*. Figure S1. Adjusted generalized additive model plots of ln-transformed PFAS concentrations with developmental problems in communication among offspring. Figure S2. Adjusted generalized additive model plots of ln-transformed PFAS concentrations with offspring developmental problems in Gross motor among offspring. Figure S3. Adjusted generalized additive model plots of ln-transformed PFAS concentrations with developmental problems in Fine motor among offspring. Figure S4. Adjusted generalized additive model plots of ln-transformed PFAS concentrations with developmental problems in Problem solving among offspring. Figure S5. Adjusted generalized additive model plots of ln-transformed PFAS concentrations with developmental problems in Personal-social skills among offspring. (DOCX 15944 kb)
Acute and persistent effects of oral glutamine supplementation on growth, cellular proliferation, and tight junction protein transcript abundance in jejunal tissue of low and normal birthweight pre-weaning piglets
Creators: name: Schregel, Johannes
name: Schulze Holthausen, Johannes
name: Sciascia, Quentin L.
name: Görs, Solvig
name: Li, Zeyang
name: Tuchscherer, Armin
name: Albrecht, Elke
name: Zentek, Jürgen
name: Metges, Cornelia C.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Swine
subject: Jejunum
subject: Age groups
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

description: Breeding for higher fertility has resulted in a higher number of low birthweight (LBW) piglets. It has been shown that LBW piglets grow slower than normal birthweight (NBW) littermates. Differences in growth performance have been associated with impaired small intestinal development. In suckling and weaning piglets, glutamine (Gln) supplementation has been associated with improved growth and intestinal development. This study was designed to examine the effects of oral Gln supplementation on growth and small intestinal parameters in LBW and NBW suckling piglets. At birth (day 0), a total of 72 LBW (1.10 ± 0.06 kg) and 72 NBW (1.51 ± 0.06) male piglets were selected. At day 1, litters were standardized to 12 piglets, and experimental piglets supplemented daily with either Gln (1 g/kg BW) or isonitrogenous amounts of Alanine (Ala) as control (1.22 g/kg BW) until day 12. Creep feed was offered from day 14 onward. Subgroups of piglets were euthanized at days 5, 12, and 26 for the analyses of jejunal morphometry, cellular proliferation, glutathione concentration and transcript abundance of tight junction proteins. From age day 11 to 21, Gln supplemented LBW (LBW-Gln) piglets were heavier than Ala supplemented LBW (LBW-Ala) littermates (P = 0.034), while NBW piglets were heavier until age day 26 compared to LBW littermates. Villus height was higher in LBW-Gln compared to LBW-Ala on age day 12 (P = 0.031). Sporadic differences among supplementation and birthweight groups were detected for jejunal cellular proliferation, cellular population and glutathione concentration, whereas age was the most dominant factor. These results show that Gln supplementation improved the growth of LBW piglets compared to LBW-Ala beyond the termination of Gln supplementation, but this was not associated with consistent effects on selected parameters of jejunal development.
title: Development of an LC-MS method for determination of nitrogen-containing heterocycles using mixed-mode liquid chromatography
Creators: name: Abdighahroudi, Mohammad Sajjad
name: Lutze, Holger V.
name: Schmidt, Torsten C.
Publisher: name: Springer
Year: 2022

description: N-containing heterocycles (NCHs) are largely used as precursors for pharmaceuticals and can enter the environment. Some NCHs have been shown to be toxic, persistent, and very mobile in the environment. Thus, they have received increasing attention in the past years. However, the analysis of these polar compounds in environmental samples is still a challenge for liquid chromatography. This paper investigates the use of mixed-mode liquid chromatography (MMLC), which has reversed-phase and ion exchange characteristics for measurements of NCHs in water. NCHs with low pKa (i.e., 5) interact by a mixture of reversed-phase/ion exchange/HILIC mechanism. It was also shown that the presented method performs well in the quantification of the majority of the selected NCHs in surface water with MDLs between 3 and 6 μg/L, a low matrix effect and recoveries in the range of 77–96% except for pyridazine exhibiting 32% were achieved. The method was successfully employed to follow the degradation of NCHs in ozonation.
Functional electrical stimulation cycling exercise after spinal cord injury: a systematic review of health and fitness-related outcomes.
Creators: name: Van Der Scheer, Jan W
name: Goosey-Tolfrey, Victoria L
name: Valentino, Sydney E
name: Davis, Glen M
name: Ho, Chester H
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Spinal cord injury
Exercise
Systematic review
Clinical Practice Guidelines
Functional Electrical Stimulation

description: ObjectivesThe objective of this review was to summarize and appraise evidence on functional electrical stimulation (FES) cycling exercise after spinal cord injury (SCI), in order to inform the development of evidence-based clinical practice guidelines.MethodsPubMed, the Cochrane Central Register of Controlled Trials, EMBASE, SPORTDiscus, and CINAHL were searched up to April 2021 to identify FES cycling exercise intervention studies including adults with SCI. In order to capture the widest array of evidence available, any outcome measure employed in such studies was considered eligible. Two independent reviewers conducted study eligibility screening, data extraction, and quality appraisal using Cochranes' Risk of Bias or Downs and Black tools. Each study was designated as a Level 1, 2, 3 or 4 study, dependent on study design and quality appraisal scores. The certainty of the evidence for each outcome was assessed using GRADE ratings ('High', 'Moderate', 'Low', or 'Very low').ResultsNinety-two studies met the eligibility criteria, comprising 999 adults with SCI representing all age, sex, time since injury, lesion level and lesion completeness strata. For muscle health (e.g., muscle mass, fiber type composition), significant improvements were found in 3 out of 4 Level 1-2 studies, and 27 out of 32 Level 3-4 studies (GRADE rating: 'High'). Although lacking Level 1-2 studies, significant improvements were also found in nearly all of 35 Level 3-4 studies on power output and aerobic fitness (e.g., peak power and oxygen uptake during an FES cycling test) (GRADE ratings: 'Low').ConclusionCurrent evidence indicates that FES cycling exercise improves lower-body muscle health of adults with SCI, and may increase power output and aerobic fitness. The evidence summarized and appraised in this review can inform the development of the first international, evidence-based clinical practice guidelines for the use of FES cycling exercise in clinical and community settings of adults with SCI. Registration review protocol: CRD42018108940 (PROSPERO).
MAKTABGACHA TA'LIM TASHKILOTI TARBIYALANUVCHISI UCHUN INTERFAOL MUHITNI YARATISH
Creators: name: Babalova, D.A.
Publisher: name: Zenodo
Year: 2024

description: Hozirda maktabgacha ta’lim tashkilotida ta’lim-tarbiya jarayoni sifati va samaradorligini oshirishda ta’limning zamonaviy usullaridan foydalanish jiddiy ahamiyatga ega. Buni amalga oshirish uchun esa, avvalo, pedagog-tarbiyachilarning o‘zlari ilg‘or pedagogik va axborotkommunikatsiya texnologiyalarini puxta o‘zlashtirgan bo‘lishlari kerakligi bayon qilingan.
О шестом технологическом укладе
Creators: name: Grinin, Leonid
name: Grinin, Anton
Publisher: name: figshare
Year: 2018
Subjects: subject: History
subject: 109999 Technology not elsewhere classified
subject: FOS: Other engineering and technologies
subject: Economics

description: В настоящей главе на базе теории принципов производства и производственных революций мы показываем взаимосвязь между К-волнами и крупнейшими технологическими переворотами в истории, а также делаем прогнозы об особенностях шестой К-волны в свете идущей с 1950-х гг. кибернетической революции. Мы предполагаем, что шестая кондратьевская волна в 2030–2040-х гг. сольется с завершающей фазой кибернетической революции(которую мы назвали фазой самоуправляемых систем). Этот период будет характеризоваться прорывом в медицинских технологиях, которые смогутобъединить вокруг себя множество других и в целом составят комплекс МАНБРИК-технологий (медицинских, аддитивных, нано-, биотехнологий, робототехники, информационных и когнитивных технологий). В главе даются некоторые прогнозы о развитии данных технологий.
Theory of pixel lensing towards M31 I: the density contribution and mass of MACHOs
Creators: name: Kerins, E.
name: Carr, B. J.
name: Evans, N. W.
name: Hewett, P.
name: Lastennet, E.
name: Du, Y. Le
name: Melchior, A. -L.
name: Smartt, S. J.
name: Valls-Gabaud, D.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: POINT-AGAPE is an Anglo-French collaboration which is employing the Isaac Newton Telescope (INT) to conduct a pixel-lensing survey towards M31. In this paper we investigate what we can learn from pixel-lensing observables about the MACHO mass and fractional contribution in M31 and the Galaxy for the case of spherically-symmetric near-isothermal haloes. We employ detailed pixel-lensing simulations which include many of the factors which affect the observables. For a maximum MACHO halo we predict an event rate in V of up to 100 per season for M31 and 40 per season for the Galaxy. However, the Einstein radius crossing time is generally not measurable and the observed full-width half-maximum duration provides only a weak tracer of lens mass. Nonetheless, we find that the near-far asymmetry in the spatial distribution of M31 MACHOs provides significant information on their mass and density contribution. We present a likelihood estimator for measuring the fractional contribution and mass of both M31 and Galaxy MACHOs which permits an unbiased determination to be made of MACHO parameters, even from data-sets strongly contaminated by variable stars. If M31 does not have a significant population of MACHOs in the mass range 0.001-1 Solar masses strong limits will result from the first season of INT observations. Simulations based on currently favoured density and mass values indicate that, after three seasons, the M31 MACHO parameters should be constrained to within a factor four uncertainty in halo fraction and an order of magnitude uncertainty in mass (90% confidence). Interesting constraints on Galaxy MACHOs may also be possible. For a campaign lasting ten years, comparable to the lifetime of current LMC surveys, reliable estimates of MACHO parameters in both galaxies should be possible. (Abridged)
description: 21 pages, 14 figures. Submitted to MNRAS
title: ESLO1: entretien 004_B
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
The structures of ordered defects in thiocyanate analogues of Prussian Blue.
Creators: name: Cliffe, Matthew J
name: Keyzer, Evan N
name: Bond, Andrew D
name: Astle, Maxwell A
name: Grey, Clare P
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: We report the structures of six new divalent transition metal hexathiocyanatobismuthate frameworks with the generic formula , M = Mn, Co, Ni and Zn. These frameworks are defective analogues of the perovskite-derived trivalent transition metal hexathiocyanatobismuthates MIII[Bi(SCN)6]. The defects in these new thiocyanate frameworks order and produce complex superstructures due to the low symmetry of the parent structure, in contrast to the related and more well-studied cyanide Prussian Blue analogues. Despite the close similarities in the chemistries of these four transition metal cations, we find that each framework contains a different mechanism for accommodating the lowered transition metal charge, making use of some combination of Bi(SCN)6 3- vacancies, MBi antisite defects, water substitution for thiocyanate, adventitious extra-framework cations and reduced metal coordination number. These materials provide an unusually clear view of defects in molecular framework materials and their variety suggests that similar richness may be waiting to be uncovered in other hybrid perovskite frameworks.
Curbing customer-to-customer misbehavior contagion in the sharing economy
Creators: name: Danatzis, Ilias
name: Möller-Herm, Jana
name: Herm, Steffen
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Customer misbehavior
subject: Sharing economy
subject: Customer-to-customer interactions
subject: Blame attributions
subject: Social norms
subject: Anti-misbehavior measures
subject: 300 Sozialwissenschaften::330 Wirtschaft::330 Wirtschaft

description: The sharing economy has fundamentally transformed customers’ lives. Providing short-term access to resources, however, creates environments in which customers regularly become the target of other customers’ misbehavior, either personally or toward shared resources. Although this customer-to-customer (C2C) misbehavior is known to be contagious, the reasons for its spread and the effectiveness of containment measures across sharing economy markets remain unclear. Three experiments reveal the moderating role of on-site supervision: platform-provider-directed blame attributions drive C2C misbehavior contagion in settings with formal on-site supervision, while social norms underlie contagion when on-site supervision is absent. Perpetrator-directed blame attributions reverse contagion irrespective of on-site supervision. More intrusive platform and peer-provider measures (in-person reprimands, in-app messages, and photo features) are most effective at curbing contagion by reducing social norms to misbehave and shifting blame to the perpetrator. However, these measures are only effective at certain C2C misbehavior severity levels for different sharing economy market types.
Panel collapse and its applications
Creators: name: Hagen, Mark F.
name: Touikan, Nicholas W. M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics

description: We describe a procedure called panel collapse for replacing a CAT(0) cube complex $Ψ$ by a "lower complexity" CAT(0) cube complex $Ψ_\bullet$ whenever $Ψ$ contains a codimension-$2$ hyperplane that is extremal in one of the codimension-$1$ hyperplanes containing it. Although $Ψ_\bullet$ is not in general a subcomplex of $Ψ$, it is a subspace consisting of a subcomplex together with some cubes that sit inside $Ψ$ "diagonally". The hyperplanes of $Ψ_\bullet$ extend to hyperplanes of $Ψ$. Applying this procedure, we prove: if a group $G$ acts cocompactly on a CAT(0) cube complex $Ψ$, then there is a CAT(0) cube complex $Ω$ so that $G$ acts cocompactly on $Ω$ and for each hyperplane $H$ of $Ω$, the stabiliser in $G$ of $H$ acts on $H$ essentially. Using panel collapse, we obtain a new proof of Stallings's theorem on groups with more than one end. As another illustrative example, we show that panel collapse applies to the exotic cubulations of free groups constructed by Wise. Next, we show that the CAT(0) cube complexes constructed by Cashen-Macura can be collapsed to trees while preserving all of the necessary group actions. (It also illustrates that our result applies to actions of some non-discrete groups.) We also discuss possible applications to quasi-isometric rigidity for certain classes of graphs of free groups with cyclic edge groups. Panel collapse is also used in forthcoming work of the first-named author and Wilton to study fixed-point sets of finite subgroups of $\mathrm{Out}(F_n)$ on the free splitting complex. Finally, we apply panel collapse to a conjecture of Kropholler, obtaining a short proof under a natural extra hypothesis.
description: Revised according to referee comments. This version accepted in "Groups, Geometry, and Dynamics"
title: The untitled title in the XX century art: revolutionary aspects and implications
Creators: name: Ianeselli, Chiara
Publisher: name: IMT Alti Studi Lucca
Year: 2021

description: The ubiquitous abundance of the title untitled, in private hands as well as in museum collections, requires a more complex analysis. Titles deeply shape the reception of works of art, being considered a fundamental mediation point between the artist and the spectator. They have a major impact on the visual experience: the decision of not giving a title has significant ramifications, which must be further investigated. The goal of the present research is to comprehend what consequences the untitled title conveyed, and to define, through specific case studies and resulting interpreting categories, how and why it has been used, until becoming an unquestioned "term/definition" today. The untitled title, a topic that has received little attention, demands a thorough examination because it is linked to significant cultural transformations in society and an increasing concentration on spectatorship. Despite being extraordinary common, the lack of a title, or the untitled title, has not so far been documented and addressed: museum inventories even do not distinguish between the untitled title, as the actual lack of the title, and the Untitled title, as the result of an authorial choice. The core questions of the research focus on how and why so many works of art are titled untitled and on all the implications the use of this term has. The project has been developed thanks to primary sources such as titles on works of art and declarations of artists, which refer explicitly or not directly to the use of the Untitled; secondary sources such as reflections of art historians, curators, critics, scholars and gallery owners. A direct dialogue with scholars, who have conducted research on artists that have purposefully chosen the Untitled title also belongs to the latter category. The research has led to a clear definition of various classifications of use of the untitled as a title, allowing for key distinctions. Secondly, it has allowed to trace the art historical roots of the Untitled title, in particular by looking at declarations and writings of artists on the specific topic of titling. Furthermore, this research has enabled for the identification and better contextualization of the term Untitled, analysing in particular exhibitions and catalogs. It has been possible to demonstrate how the reasons behind the use of the title Untitled as a title can significantly differ, as for example in the case of artists affiliated with Abstract Expressionism, Minimalism and Arte povera. The project has also illustrated how the untitled title is a complicated issue in today's exhibition of works, particularly in relation to label definition. The Untitled title's revolutionary potency has waned in recent decades, and it has now become a popular term.
How defects in lanthanum iron manganite perovskite structures promote the catalytic reduction of NO by CO
Creators: name: Mohammadi, Asghar
name: Thurne, Christoph W.
name: Haug, Leander
name: Bekheet, Maged F.
name: Müller, Julian T.
name: Gurlo, Aleksander
name: Hejny, Clivia
name: Nezhad, Parastoo Delir Kheyrollahi
name: Winkler, Daniel
name: Riedel, Wiebke
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: In situ X-ray photoelectron spectroscopy
subject: In situ X-ray diffraction
subject: Defects
subject: Nitrogen oxide abatement
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: Adjusting the defect level during synthesis of A- and B-site deficient lanthanum iron manganite (LFM) perovskites shows that non-stoichiometry can beneficially influence the catalytic reactivity to N2 in the reduction of NO by CO on noble metal-free LFM-based perovskites. Optimal steering of La deficiency and the associated redox chemistry to reduce the near-surface regions during catalytic operation at low temperatures is the key factor. Surface enrichment by reducible B site cations and a proper design of structural defects resulting from the optimum introduction of La defects exclusively cause in-situ reduction of surface-near regions by CO oxidation, as well as formation of oxygen vacancies for enhanced NO and N2O reactivity. Excess doping with defects causes structural instability and continuous supply of oxygen from the catalyst bulk to the surface at elevated temperatures. Introduction of B site vacancies leads to surface enrichment by non-reducible lanthanum cations, causing suppressed catalyst activity undercutting even stoichiometric LFM.
Formation of Few-Body Clusters in Nuclear Matter
Creators: name: Beyer, M.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Starting from a suitably modified three-body equation to include dominant medium effects such as self energy corrections and Pauli blocking I present results on several observables relevant for the formation of light clusters in a heavy ion collision at moderate energies. Properly taking into account the medium leads to the Mott effect, larger reaction rates, in turn, faster time scales for the deuteron life time and chemical relaxation time. Within a Boltzmann-Uehling-Uhlenbeck approach to simulate the heavy ion reactions, also the total number of deuterons and the energy spectrum are significantly changed due to medium effects in the elementary cross sections entering into the collision integrals.
description: 3 pages, uses Elsevier package CRC, talk at XVI International Conference on Few-Body Problems in Physics, Taipei, Taiwan, March 6-10 2000
title: ESLO1: consultation au centre médico-psycho-pedagogique 712_B
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
Flash phase engineering of MoS2 nanofilms for enhanced photoelectrochemical performance
Creators: name: Tan, Rong
name: Liu, Yuxin
name: Tu, Yifeng
name: Loeffler, Felix F.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Flash phase engineering
subject: MoS2 nanofilms
subject: enhanced photoelectrochemical performance
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: A heterophase structure combining semiconducting 2H- and metallic 1T-MoS2 exhibits significantly enhanced photoelectrochemical performance due to the electrical coupling and synergistic effect between the phases. Therefore, site-selective effective phase engineering is crucial for the fabrication of MoS2-based photoelectrochemical devices. Here, we employed a flash phase engineering (FPE) strategy to precisely fabricate a 2H-1T heterophase structure. This technique allows simple, efficient, and precise control over the micropatterning of MoS2 nanofilms while enabling site-selective phase transition from the 1T to the 2H phase. The detection of reduced glutathione (GSH) showed an approximately 5-fold increase in sensitivity when using the electrode fabricated by FPE.
title: ESLO1: consultation au centre médico-psycho-pedagogique 705_C
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment.
Creators: name: Bermejo, Iris A
name: Navo, Claudio D
name: Castro-López, Jorge
name: Guerreiro, Ana
name: Jiménez-Moreno, Ester
name: Sánchez Fernández, Elena M
name: García-Martín, Fayna
name: Hinou, Hiroshi
name: Nishimura, Shin-Ichiro
name: García Fernández, José M
name: Mellet, Carmen Ortiz
name: Avenoza, Alberto
name: Busto, Jesús H
name: Bernardes, Gonçalo J L
name: Hurtado-Guerrero, Ramón
name: Peregrina, Jesús M
name: Corzana, Francisco
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: The Tn antigen (GalNAc-α-1-O-Thr/Ser) is a well-known tumor-associated carbohydrate determinant. The use of glycopeptides that incorporate this structure has become a significant and promising niche of research owing to their potential use as anticancer vaccines. Herein, the conformational preferences of a glycopeptide with an unnatural Tn antigen, characterized by a threonine decorated with an sp2-iminosugar-type α-GalNAc mimic, have been studied both in solution, by combining NMR spectroscopy and molecular dynamics simulations, and in the solid state bound to an anti-mucin-1 (MUC1) antibody, by X-ray crystallography. The Tn surrogate can mimic the main conformer sampled by the natural antigen in solution and exhibits high affinity towards anti-MUC1 antibodies. Encouraged by these data, a cancer vaccine candidate based on this unnatural glycopeptide and conjugated to the carrier protein Keyhole Limpet Hemocyanin (KLH) has been prepared and tested in mice. Significantly, the experiments in vivo have proved that this vaccine elicits higher levels of specific anti-MUC1 IgG antibodies than the analog that bears the natural Tn antigen and that the elicited antibodies recognize human breast cancer cells with high selectivity. Altogether, we compile evidence to confirm that the presentation of the antigen, both in solution and in the bound state, plays a critical role in the efficacy of the designed cancer vaccines. Moreover, the outcomes derived from this vaccine prove that there is room for exploring further adjustments at the carbohydrate level that could contribute to designing more efficient cancer vaccines.
Neural networks and separation of Cosmic Microwave Background and astrophysical signals in sky maps
Creators: name: Baccigalupi, C.
name: Bedini, L.
name: Burigana, C.
name: De Zotti, G.
name: Farusi, A.
name: Maino, D.
name: Maris, M.
name: Perrotta, F.
name: Salerno, E.
name: Toffolatti, L.
name: Tonazzini, A.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The Independent Component Analysis (ICA) algorithm is implemented as a neural network for separating signals of different origin in astrophysical sky maps. Due to its self-organizing capability, it works without prior assumptions on the signals, neither on their frequency scaling, nor on the signal maps themselves; instead, it learns directly from the input data how to separate the physical components, making use of their statistical independence. To test the capabilities of this approach, we apply the ICA algorithm on sky patches, taken from simulations and observations, at the microwave frequencies, that are going to be deeply explored in a few years on the whole sky, by the Microwave Anisotropy Probe (MAP) and by the {\sc Planck} Surveyor Satellite. The maps are at the frequencies of the Low Frequency Instrument (LFI) aboard the {\sc Planck} satellite (30, 44, 70 and 100 GHz), and contain simulated astrophysical radio sources, Cosmic Microwave Background (CMB) radiation, and Galactic diffuse emissions from thermal dust and synchrotron. We show that the ICA algorithm is able to recover each signal, with precision going from 10% for the Galactic components to percent for CMB; radio sources are almost completely recovered down to a flux limit corresponding to $0.7σ_{CMB}$, where $σ_{CMB}$ is the rms level of CMB fluctuations. The signal recovering possesses equal quality on all the scales larger then the pixel size. In addition, we show that the frequency scalings of the input signals can be partially inferred from the ICA outputs, at the percent precision for the dominant components, radio sources and CMB.
description: 15 pages; 6 jpg and 1 ps figures. Final version to be published in MNRAS
title: ESLO1: consultation au centre médico-psycho-pedagogique 709_B
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
О некоторых аспектах истории исследования длинноволновой динамики
Creators: name: Grinin, Leonid
name: Korotayev, Andrey
Publisher: name: figshare
Year: 2018
Subjects: subject: History
subject: Economics
subject: Sociology
subject: FOS: Sociology

description: Среди исследователей длинных волн, в том числе и среди кондратьеведов, распространено представление, что Кондратьев открыл длинные волны цен (конъюнктуры). На самом деле это не так. В настоящей главе достаточно подробно рассматривается этот вопрос. Она посвящена не столько современному состоянию исследований длинноволновой динамики, сколько некоторым аспектам начальной истории этих исследований, поскольку они изучены недостаточно, а систематизированы слабо. До сих пор нет систематического изложения ранних периодов данного исследования. Настоящая глава не претендует на системность в описании этих аспектов, но в ней сделана попытка уточнить и прояснить отдельные моменты, а также показать, в чем неверность некоторых распространенных утверждений. В отличие от добросовестного заблуждения в том, что Кондратьев открыл длинные волны, иногда встречается и противоположное ему: Кондратьев ничего не внес нового (а то, что внес, оказалось неправильным) и, по сути, заимствовал идею длинных волн и их структуры у других – прежде всего у своего учителя М. И. Туган-Барановского. Насколько это заблуждение «добросовестное», мы и показываем в данной главе.
Additional file 1: of Detection and genetic characteristics of porcine circovirus 3 based on oral fluids from asymptomatic pigs in central China
Creators: name: Guo, Zhenhua
name: Li, Xiang
name: Deng, Ruiguang
name: Zhang, Gaiping
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Table S1. Sequence information in this study. (DOC 89 kb)
The Power Spectrum of Microwave Background Temperature Anisotropies Measured by the Tenerife Experiment
Creators: name: Atrio-Barandela, F.
name: Gottl"ober, S.
name: M"ucket, J. P.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We determine the slope of the power spectrum of the matter perturbations from the Tenerife observations of the cosmic background radiation temperature anisotropies. We compute the projected radiation anisotropy power spectrum measured by this experiment and study its dependence with respect to the slope of the temperature anisotropy spectrum on the sky. We show that Tenerife alone implies the upper bound on the spectral index of $m \le 3$. Stronger conclusions can not be reached due to the small data set. The method proposed can be applied to any small scale experiment. Sampling the same region of the skywith different window functions could probe the slope of the radiation anisotropy power spectrum at different scales and confirm the presence of Doppler peaks.
description: 10 pages with figures, Postscript, (accepted by ApJ)
Opening Heaven’s Door: Public Opinion and Congressional Votes on the 1965 Immigration Act
Creators: name: Facchini, Giovanni
name: Hatton, Timothy J.
name: Steinhardt, Max F.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: 1965 Immigration Act
subject: U.S.A.
subject: immigration policy
subject: 900 Geschichte und Geografie::970 Geschichte Nordamerikas::973 Geschichte der USA

description: The 1965 Immigration Act represented a radical shift in U.S. policy, which has been credited with dramatically expanding the volume and changing the composition of immigration. Its passing has often been described as the result of political machinations negotiated within Congress without regard to public opinion. We show that congressional voting was consistent with public opinion on abolishing the country-of-origin quotas but not with the desire to limit the volume of immigration. While the former initially reflected attitudes toward civil rights, the latter is consistent with contemporary expectations that the expansion in numbers would be modest.
Supplementary document for Plasmonic hollow fibers with distributed inner-wall hotspots for direct SERS detection of flowing liquids - 5096262.pdf
Creators: name: Mu, Yunyun
name: Liu, Miao
name: Li, Jiajun
name: Zhang, Xinping
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Figures S1, S2, S3
Supramolecular catalysis by recognition-encoded oligomers: discovery of a synthetic imine polymerase.
Creators: name: Gabrielli, Luca
name: Hunter, Christopher A
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: All key chemical transformations in biology are catalysed by linear oligomers. Catalytic properties could be programmed into synthetic oligomers in the same way as they are programmed into proteins, and an example of the discovery of emergent catalytic properties in a synthetic oligomer is reported. Dynamic combinatorial chemistry experiments designed to study the templating of a recognition-encoded oligomer by the complementary sequence have uncovered an unexpected imine polymerase activity. Libraries of equilibrating imines were formed by coupling diamine linkers with monomer building blocks composed of dialdehydes functionalised with either a trifluoromethyl phenol (D) or phosphine oxide (A) H-bond recognition unit. However, addition of the AAA trimer to a mixture of the phenol dialdehyde and the diamine linker did not template the formation of the DDD oligo-imine. Instead, AAA was found to be a catalyst, leading to rapid formation of long oligomers of D. AAA catalysed a number of different imine formation reactions, but a complementary phenol recognition group on the aldehyde reaction partner is an essential requirement. Competitive inhibition by an unreactive phenol confirmed the role of H-bonding in substrate recognition. AAA accelerates the rate of imine formation in toluene by a factor of 20. The kinetic parameters for this enzyme-like catalysis are estimated as 1 × 10-3 s-1 for k cat and the dissociation constant for substrate binding is 300 μM. The corresponding DDD trimer was found to catalyse oligomerisation the phosphine oxide dialdehyde with the diamine linker, suggesting an important role for the backbone in catalysis. This unexpected imine polymerase activity in a duplex-forming synthetic oligomer suggests that there are many interesting processes to be discovered in the chemistry of synthetic recognition-encoded oligomers that will parallel those found in natural biopolymers.
ВВЕДЕНИЕ Юбилей Н. Д. Кондратьева в свете современных проблем мировой экономики
Creators: name: Grinin, Leonid
name: Korotayev, Andrey
name: V. Bondarenko
name: R. Grinberg
Publisher: name: figshare
Year: 2018
Subjects: Economics

description: Есть исследователи, проблематика работ и теории которых остаются актуальны-ми длительное время и после их смерти. К числу таких, несомненно, относится иНиколай Дмитриевич Кондратьев – замечательный российский экономист, одиниз тех, чье имя довольно широко известно и за рубежом. И эту актуальность егоидей тем более важно отметить в ознаменование 125-летнего юбилея Н. Д. Конд-ратьева. Именно этой теме – связи творчества Кондратьева и проблем современ-ной экономики и экономической науки – и посвящено данное юбилейное издание.Биографии и отдельным аспектам творчества ученого отведены несколько глав вэтой книге. Тем не менее нельзя не сказать хотя бы немного об этой личности иво Введении.Будучи крестьянским сыном, Николай Дмитриевич сумел реализовать своиспособности и уже в молодые годы стать профессором экономики. В одном изсуздальских писем (от 2 мая 1938 г.) он, как бы подводя итоги своей деятельно-сти, писал: «…я не получил никакого воспитания, как и большинство крестьян-ских детей. Поэтому мой характер сложился стихийно в суровой жизненной шко-ле, которую мне пришлось в свое время пройти. Но не обладай я своим характе-ром – я бы никогда не пробился от сохи до профессорской кафедры» (Кондратьев1991 [1931]: 559).
Isolated Photons at Hadron Colliders at O($αalpha_s^2$) (I): Spin Averaged Case
Creators: name: Gordon, L. E.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The cross sections for isolated and non-isolated prompt photon production with unpolarized hadron beams are studied at order $αα_s^2$. Two methods of performing the calculations are compared. One uses purely analytic techniques and the second uses a combination of analytic and Monte Carlo techniques to perform the phase-space integrations. The results of the analytic and Monte Carlo methods are compared both before and after isolation cuts are placed on the photon. Fragmentation contributions are included at next-to-leading order in the analytic case, and the question of the infrared sensitivity of this contribution once isolation is implemented is addressed. Numerical results are presented and compared with the latest CDF data for $p\bar{p} \to γ+X$ using the latest parton densities for the proton.
description: 29 pages, 14 figures
Dust Source Activation Frequency in the Horn of Africa
Creators: name: Kunkelova, Tereza
name: Crocker, Anya J.
name: Wilson, Paul A.
name: Schepanski, Kerstin
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Horn of Africa
subject: dust source activation frequency
subject: MSG-SEVIRI
subject: 500 Naturwissenschaften und Mathematik::550 Geowissenschaften, Geologie::551 Geologie, Hydrologie, Meteorologie

description: Mineral dust aerosols play an important role in Earth's climate through interactions with incoming solar radiation, clouds, and the atmosphere. However, dust sources in the Horn of Africa (HoA) and controls on their activation are poorly documented. Here, we use fifteen-minute Meteosat Second Generation Spinning Enhanced Visible and Infrared Imager dust index images to identify HoA dust source areas and to quantify their activation frequency in 1° × 1° resolution from 2006 to 2010. Around half of all recorded dust events occur in boreal summer, mostly between 8:00 and 16:00 local time. They are driven by meso- to regional scale meteorological mechanisms including the breakdown of the nocturnal low-level jets, land-sea breezes, and haboobs. By far the most dust-active region in the HoA is the Afar Triangle (>77% of all recorded dust events) which features the Afar and Danakil depressions and is fed by the Awash River. Despite experiencing strong and persistent southwest summer monsoon winds, dust activation on the Somali Peninsula is less significant. A composite of our map with data for North Africa and westernmost Asia shows that the HoA is a striking latitudinal anomaly with dust activation extending deep into the equatorial belt. Our data also reveal that dust activation is unusually seasonal with ∼40% of events occurring in June and July. Our findings show that aridity and mean wind strength alone are poor predictors of dust activation and underscore the strong control exerted by the availability of readily deflated unconsolidated riverine and lacustrine sediments.
Additional file 1: of Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimerâ s disease
Creators: name: Weston, Philip
name: Poole, Teresa
name: OâConnor, Antoinette
name: Heslegrave, Amanda
name: Ryan, Natalie
name: Liang, Yuying
name: Druyeh, Ronald
name: Mead, Simon
name: Blennow, Kaj
name: Schott, Jonathan
name: Frost, Chris
name: Zetterberg, Henrik
name: Fox, Nick
Publisher: name: figshare
Year: 2019
Subjects: Medicine
Biological Sciences not elsewhere classified
Computational Biology

description: Table S1. Participantsâ family mutations. (DOCX 17 kb)
Remarks on $p$-monotone operators
Creators: name: Bueno, Orestes
name: Cotrina, John
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optimization and Control (math.OC)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 47H04, 47H05, 49J53

description: In this paper, we deal with three aspects of $p$-monotone operators. First we study $p$-monotone operators with a unique maximal extension (called pre-maximal), and with convex graph. We then deal with linear operators, and provide characterizations of $p$-monotonicity and maximal $p$-monotonicity. Finally we show that the Brezis-Browder theorem preserves $p$-monotonicity in reflexive Banach spaces.
description: 15 pages
Dithering Strategies for Efficient Self-Calibration of Imaging Arrays
Creators: name: Arendt, Richard G.
name: Fixsen, D. J.
name: Moseley, S. Harvey
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: With high sensitivity imaging arrays, accurate calibration is essential to achieve the limits of detection of space observatories. One can simultaneously extract information about the scene being observed and the calibration properties of the detector and imaging system from redundant dithered images of a scene. There are large differences in the effectiveness of dithering strategies for allowing the separation of detector properties from sky brightness measurements. In this paper, we quantify these differences by developing a figure of merit (FOM) for dithering procedures based on their usefulness for allowing calibration on all spatial scales. The figure of merit measures how well the gain characteristics of the detector are encoded in the measurements, and is independent of the techniques used to analyze the data. Patterns similar to the antenna arrangements of radio interferometers with good u-v plane coverage, are found to have good figures of merit. We present patterns for both deep surveys of limited sky areas and for shallow surveys. By choosing a strategy that encodes the calibration in the observations in an easily extractable way, we enhance our ability to calibrate our detector systems and to reach the ultimate limits of sensitivity which are required to achieve the promise of many missions.
description: Scheduled for ApJ, June 10, 2000 (22 pages, 9 figures)
title: ESLO1: entretien 008_B
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
Electrostatically-directed Pd-catalysis in combination with C-H activation: site-selective coupling of remote chlorides with fluoroarenes and fluoroheteroarenes.
Creators: name: Golding, William A
name: Phipps, Robert J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Systems incorporating catalyst-substrate non-covalent interactions are emerging as a versatile approach to address site-selectivity challenges in remote functionalization reactions. Given the achievements that have been made in this regard using metals such as iridium, manganese and rhodium, it is surprising that non-covalent catalyst direction has not been utilized in reactions incorporating palladium-catalyzed C-H activation steps, despite palladium being arguably the most versatile metal for C-H activation. Herein, we demonstrate that electrostatically directed, site-selective C-Cl oxidative addition is compatible with a subsequent C-H activation step, proceeding via a concerted metalation deprotonation-type mechanism. This results in site-selective cross-coupling of dichloroarenes with fluoroarenes and fluoroheteroarenes, with selectivity controlled by catalyst structure. This study demonstrates that Pd-catalyzed C-H activation can be used productively in combination with a non-covalently-directed mode of catalysis, with important implications in both fields.
title: ESLO1: entretien 042_B
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826