cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin
Creators: name: Goding, Colin
name: Strahl, Brian D.
name: Savitsky, Pavel
name: Friedrichsen, Hans
name: Krojer, Tobias
name: Picaud, Sarah
name: Gingras, Anne-Claude
name: Fujisawa, Takao
name: Wang, Chen-Yi
name: Krajewski, Krzysztof
name: Shanle, Erin K.
name: Schapira, Matthieu
name: Kanapin, Alexander
name: Lambert, Jean-Philippe
name: Samsonova, Anastasia
name: Filippakopoulos, Panagis
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Elucidation of interactions involving DNA and histone post-translational-modifications (PTMs) is essential for providing insight into complex biological functions. Reader assemblies connected via flexible linkages facilitate avidity and increase affinity, however little is known of the contribution to the recognition process of multiple PTMs due to rigidity in the absence of conformational flexibility. We report here the high resolution crystal structure of the triple-reader module (PHD-Bromo-PWWP) of ZMYND8 which forms a stable unit capable of simultaneously recognizing multiple histone PTMs, while presenting a charged platform for association with DNA. Single domain disruptions destroy the functional network of interactions initiated by ZMYND8, impairing recruitment to sites of DNA damage. Our data establish proof-of-principle that rigidity can be compensated by concomitant DNA and histone PTM interactions, maintaining multivalent engagement of transient chromatin states, thus identifying an important underappreciated role for rigid multivalent reader modules in nucleosome binding and chromatin function.
Do early warning signals precede large symptom improvements in depression?
Creators: name: Helmich, Marieke
name: Snippe, Evelien
name: Kunkels, Yoram
name: Riese, Harriette
name: Smit, Arnout
name: Wichers, M.
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Mental Disorders
subject: Psychoanalysis and Psychotherapy
subject: Clinical Psychology
subject: Psychiatry and Psychology
subject: Medicine and Health Sciences
subject: Mental and Social Health
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Psychological Phenomena and Processes
subject: autocorrelation at lag-1
subject: complex systems
subject: critical transition
subject: depression
subject: dynamical systems
subject: early warning signals
subject: ecological momentary assessment
subject: exploratory analysis
subject: major depressive disorder
subject: phase transition
subject: recovery
subject: symptom improvement
subject: time series data
subject: variance
subject: within-persons analysis

description: This registration covers the analysis plan to answer the primary research question of the TRANS-ID Recovery project: Can we find indicators of critical slowing down (CSD) in the form of early warning signals (EWS), like increases in autocorrelation at lag-1 and variance, before transitions towards improvement in depressive symptoms? Steps for further exploration are also outlined.
RNA-Polymerase I: einer spezialisierten Transkriptionsmaschine auf der Spur
Creators: name: Pilsl, Michael
name: Tschochner, Herbert
name: Griesenbeck, Joachim
name: Engel, Christoph
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: 570 Biowissenschaften, Biologie

description: In eukaryotes three major nuclear RNA Polymerases (Pols I, II and III) transcribe the genome. Pols II and III transcribe many different genes. Pol I has only one target from which it synthesizes the precursor for 3 of 4 ribosomal (r)RNAs accounting for up to 60 percent of total cellular RNA. Dedication of Pol I and its specific transcription factors to transcribe a single gene underlines the importance of rRNA synthesis. Research in Regensburg aims at understanding mechanism(s) of Pol I transcription.
Strain Doping: Reversible Single-Axis Control of a Complex Oxide Lattice via Helium Implantation
Creators: name: Guo, Hangwen
name: Dong, Shuai
name: Rack, Philip D.
name: Budai, John D.
name: Beekman, Christianne
name: Gai, Zheng
name: Siemons, Wolter
name: Gonzalez, C. M.
name: Timilsina, R.
name: Wong, Anthony T.
name: Herklotz, Andreas
name: Snijders, Paul C.
name: Dagotto, Elbio
name: Ward, Thomas Z.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report on the use of helium ion implantation to independently control the out-of-plane lattice constant in epitaxial La0.7Sr0.3MnO3 thin films without changing the in-plane lattice constants. The process is reversible by a vacuum anneal. Resistance and magnetization measurements show that even a small increase in the out-of-plane lattice constant of less than 1% can shift the metal-insulator transition and Curie temperatures by more than 100 °C. Unlike conventional epitaxy-based strain tuning methods which are constrained not only by the Poisson effect but by the limited set of available substrates, the present study shows that strain can be independently and continuously controlled along a single axis. This permits novel control over orbital populations through Jahn-Teller effects, as shown by Monte Carlo simulations on a double-exchange model. The ability to reversibly control a single lattice parameter substantially broadens the phase space for experimental exploration of predictive models and leads to new possibilities for control over materials' functional properties.
title: The World Heritage Convention at 50: management, credibility and sustainable development (accepted)
Creators: name: Labadi, Sophia
Publisher: name: Emerald
Year: 2022

description: Purpose: The World Heritage Convention has reached a milestone and this year, in 2022, it is celebrating its 50th anniversary. The aim of this article is to review whether and how the goals of the Strategic Action Plan (SAP) for the Implementation of the World Heritage Convention (2012-2022) have been reached. Methodology/approach: This article starts by considering the outcomes for three of the SAP goals, dealing with protection and management; the credibility of the World Heritage List; and sustainable development, using additional information from the final implementation report of the SAP (UNESCO, 2021a), which provides key performance indicators and the implementation status for each goal and associated outcomes. This articles then compares and contrasts available data, trends, and examples to provide more in-depth analyses of the implementation of the three goals. Data have been gathered from my own research and from the work of other academics and practitioners. Findings: The article finds several key positive changes, including the recent revisions of the Operational Guidelines to include provisions from the 2015 Policy on World Heritage and Sustainable Development. However, a number of concerning or worsening trends relating to the protection and management of the World Heritage List, its increasing lack of credibility, and sustainable development make it difficult to conclude that the implementation of the goals has been positive. The article concludes with suggestions for addressing these issues. Originality: This paper fills a gap, as not much has yet been published on the state of implementation of the Convention at 50 years old.
description: Author's Accepted Manuscript
title: Great trochanter as a preserved part of proximal femur in children with proximal femoral focal deficiency
Creators: name: Mangov, Andriy
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Musculoskeletal joint
subject: Paediatric
subject: Musculoskeletal soft tissue
subject: MR
subject: CT
subject: Conventional radiography
subject: Diagnostic procedure
subject: Comparative studies
subject: Diagnostic procedure
subject: Congenital

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Proximal femoral focal deficiency is a rare congenital limb anomalywith failure development of proximal part of femur.Most scientific articles pointed that proximal part of femur partially or completely absent [1]. The purpose of our study was to...
artificial large-scale engineering
Creators: name: 陈, 绪言
name: Gao, Gang
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310801
subject: Phycology (incl. marine grasses)
classificationCode: 310302
subject: Community ecology (excl. invasive species ecology)

description: artificial large-scale engineering
Cooper pair splitting in a nanoSQUID geometry at high transparency
Creators: name: Jacquet, R.
name: Rech, J.
name: Jonckheere, T.
name: Zazunov, A.
name: Martin, T.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We describe a Josephson device composed of two superconductors separated by two interacting quantum dots in parallel, as a probe for Cooper pair splitting. In addition to sequential tunneling of electrons through each dot, an additional transport channel exists in this system: crossed Andreev reflection, where a Cooper pair from the source is split between the two dots and recombined in the drain superconductor. Unlike non-equilibrium scenarios for Cooper pair splitting which involves superconducting/normal metal "forks", our proposal relies on an Aharonov-Bohm measurement of the DC Josephson current when a flux is inserted between the two dots. We provide a path integral approach to treat arbitrary transparencies, and we explore all contributions for the individual phases ($0$ or $π$) of the quantum dots. We propose a definition of the Cooper pair splitting efficiency for arbitrary transparencies, which allows us to find the phase associations which favor the crossed Andreev process. Possible applications to experiments using nanowires as quantum dots are discussed.
description: 12 pages, 13 figures
MPEC 2024-R127 : 2019 VH57
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2019 VH57

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: Age dependence of spleen- and muscle-corrected hepatic signal enhancement on hepatobiliary phase gadoxetate MRI
Creators: name: Matoori, Simon
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Liver
subject: MR
subject: Contrast agent-intravenous
subject: Artifacts

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Clinical Need for Liver Function Assessment Currently, there is an unmet clinical need for a test to localize and quantify an impaired liver function[1]. In surgical liver resection, for instance, a precise evaluation of liver function would be...
Learning efficiency correlates of using SuperMemo with specially crafted Flashcards in medical scholarship
Creators: name: Pujo, Alexis
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Educational Methods
subject: Education

description: Computer-assisted learning has been growing in popularity in higher education and in the research literature. A subset of these novel approaches to learning claim that predictive algorithms called Spaced Repetition can significantly improve retention rates of studied knowledge while minimizing the time investment required for learning. SuperMemo is a brand of commercial software and the editor of the SuperMemo spaced repetition algorithm. Medical scholarship is well known for requiring students to acquire large amounts of information in a short span of time. Anatomy, in particular, relies heavily on rote memorization. Using the SuperMemo web platform we are creating a non-randomized trial, inviting medical students completing an anatomy course to take part. Usage of SuperMemo as well as a performance test will be measured and compared with a concurrent control group who will not be provided with the SuperMemo Software.
title: Are breast cancer MR imaging features helpful for selecting patients who would be candidate to axillary dissection?
Creators: name: De Narda, Francesca
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Breast
subject: Oncology
subject: MR
subject: Staging
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Background Axillary nodal staging is an important step in pretherapeutic evaluation of patients with primary breast cancer. On one hand, preoperative identification of nodal metastasis is important to plan neoadjuvant therapy as well as avoiding...
title: Facile Ring Enlargement of Azulene to Give the Cyclopentacyclononene System by Dipolar Cycloaddition
Creators: name: Hafner, Klaus
name: Lindner, Hans Jörg
name: Ude, Werner
Publisher: name: Wiley
Year: 2023

description: The cyclopentacyclononene derivative (3). the first compound to contain this ring system and also the first stable cyclononatetraene not to have an annelated benzene ring, has been synthesized from the “ethanoazulene” (1). This synthesis is possible because azulene reacts readily with the ynamine (2), to give the tricyclic species (4). Although 4,6,8-methylazulene initially gives the desired ring system (5), immediate transannular bonding occurs. The bracket in (1) prevents this reaction.
Strongly interacting Bose-Fermi mixtures in one dimension
Creators: name: Hu, Haiping
name: Guan, Liming
name: Chen, Shu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We study one-dimensional strongly interacting Bose-Fermi mixtures by both the exact Bethe-ansatz method and variational perturbation theory within the degenerate ground state subspace of the system in the infinitely repulsive limit. Based on the exact solution of the one-dimensional Bose-Fermi gas with equal boson-boson and boson-fermion interaction strengths, we demonstrate that the ground state energy is degenerate for different Bose-Fermi configurations and the degeneracy is lifted when the interaction deviates the infinitely interacting limit. We then show that the ground properties in the strongly interacting regime can be well characterized by using the variational perturbation method within the degenerate ground state subspace, which can be applied to deal with more general cases with anisotropic interactions and in external traps. Our results indicate that the total ground-state density profile in the strongly repulsive regime behaves like the polarized noninteracting fermions, whereas the density distributions of bosons and fermions display different properties for different Bose-Fermi configurations and are sensitive to the anisotropy of interactions.
description: 11 pages, 3 figures, Version published in "Focus on Strongly Interacting Quantum Gases in One Dimension" (NJP, IOP) dedicated to Marvin D. Girardeau (1930-2015)
Impulsive decision-making predicts the course of substance-related and addictive disorders
Creators: name: Kräplin, Anja
Publisher: name: Technische Universität Dresden
Year: 2018
Subjects: subject: Psychology
subject: FOS: Psychology

description: Data and do-files for the analyses presented in the paper "Impulsive decision-making predicts the course of substance-related and addictive disorders" Aims of the analyses: To test whether impulsive decision-making (1) differs between individuals with substance use disorders (SUD) or non-substance-related addictive disorders (ND) and healthy controls and (2) predicts the course of SUD and ND severity after one year. Design of the study: Baseline and one year follow-up of a prospective-longitudinal community study. Setting of the study: Clinical interviews and behavioural tasks in the laboratory. Participants: 338 individuals between age 20 and 26 were selected from a random sample from the registration office files of Dresden, Germany. Participants fulfilled the criteria for one of three groups: SUD, ND, or healthy controls. After one year, we assessed 313 participants again (93%). Measurements: ND and SUD severity were operationalized with number of DSM-5 symptoms (partly modified for ND) and quantity-frequency indices of use. Four tasks were applied to assess independent facets of impulsive decision-making: 1) delay discounting, 2) risk seeking for gains and 3) for losses, and 4) loss aversion.
title: Comparison between Gaussian and non-Gaussian diffusion models in hepatic metastatic disease and normal liver
Creators: name: Papanikolaou, Nickolas
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Liver
subject: Oncology
subject: MR-Diffusion/Perfusion
subject: Statistics
subject: Metastases

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of the current poster was to apply and compare four diffusion models including mono-exponentialand bi-exponentialboth Gaussian and non-Gaussian, in hepatic metastases andnormal liver tissue. Gaussian mono-exponential model associated to the...
Oscillatory Dynamics in the Frontoparietal Attention Network during Sustained Attention in the Ferret
Creators: name: Yu, Chunxiu
name: Radtke-Schuller, Susanne
name: Fröhlich, Flavio
name: Alagapan, Sankaraleengam
name: Stitt, Iain
name: Sellers, Kristin K.
name: Li, Yuhui
name: Zhou, Zhe Charles
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Sustained attention requires the coordination of neural activity across multiple cortical areas in the frontoparietal network, in particular the prefrontal cortex (PFC) and posterior parietal cortex (PPC). Previous work has demonstrated that activity in these brain regions is coordinated by neuronal oscillations of the local field potential (LFP). However, the underlying coordination of activity in terms of organization of single unit (SU) spiking activity has remained poorly understood, particularly in the freely moving animal. We found that long-range functional connectivity between anatomically connected PFC and PPC was mediated by oscillations in the theta frequency band. SU activity in PFC was phase locked to theta oscillations in PPC, and spiking activity in PFC and PPC was locked to local high-gamma activity. Together, our results support a model in which frequency-specific synchronization mediates functional connectivity between and within PFC and PPC of the frontoparietal attention network in the freely moving animal.
title: Charles Lassart
Creators: name: Serrão, Vera da Cunha
name: Conceição, Margarida
Publisher: name: CHAM, Faculdade de Ciências Sociais e Humanas, Universidade Nova de Lisboa
Year: 2022

description: Entrada biográfica sobre Charles Lassart, na plataforma eViterbo
description: Serrão, Vera da Cunha e Conceição, Margarida Tavares da. 2022. Charles Lassart in eViterbo. CHAM, Faculdade de Ciências Sociais e Humanas, Universidade Nova de Lisboa. eISBN: 978-989-8492-77-7
Replication of Elliot et al. (2010)'s Experiment 3 by The School of Psychology of Queen's University Belfast
Creators: name: Dessing, Joost
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: This is an L2 Undergraduate group project in which we replicate an experiment reported by Elliott et al. (2010) on the effect of red coloured background on the perceived attractiveness, desired sexual behaviours, and perceived likability of males shown on a picture.
title: Brain CT-perfusion: correlation between completeness of the circle of Willis and haemodynamic changes in cases of not-acute atherosclerotic occlusion of main brachiocephalic arteries
Creators: name: Vishnevskaia, Anna
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Vascular
subject: Anatomy
subject: Neuroradiology brain
subject: CT-Angiography
subject: CT
subject: CT-Quantitative
subject: Diagnostic procedure
subject: Contrast agent-intravenous
subject: Arteriosclerosis
subject: Ischaemia / Infarction

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Aterosclerosis is a chronic systemic disease which causes gradual narrowing of the arterial blood vessels up to occlusion. According to the data from studies, in group of patients over 65 years old, up to 75% of men and 64% of women could have...
Replication of Seli, Risko, & Smilek (2016) at the School of Psychology or Queen's University Belfast
Creators: name: Dessing, Joost
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: This is a study that replicates Seli, Risko, & Smilek (2016) (https://journals.sagepub.com/doi/abs/10.1177/0956797616634068) in an L2 Undergraduate Group project at The School of Psychology of Queen's University Belfast. This is one of the CREP projects (https://osf.io/wfc6u/), but time prevented us from going through the entire process.
Tunneling Magnetoresistance in Junctions Composed of Ferromagnets and Time-Reversal Invariant Topological Superconductors
Creators: name: Yan, Zhongbo
name: Wan, Shaolong
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Tunneling Magnetoresistance between two ferrromagnets is an issue of fundamental importance in spintronics. In this work, we show that tunneling magnetoresistance can also emerge in junctions composed of ferromagnets and time-reversal invariant topological superconductors without spin-rotation symmetry. Here the physical origin is that when the spin-polarization direction of injected electron from the ferromagnet lying in the same plane of the spin-polarization direction of Majorana zero modes, the electron will undergo a perfect spin-equal Andreev reflection, while injected electrons with other spin-polarization direction will be partially Andreev reflected and partially normal reflected, which consequently have a lower conductance, and therefore, the magnetoresistance effect emerges. Compared to conventional magnetic tunnel junctions, an unprecedented advantage of the junctions studied here is that arbitrary high tunneling magnetoresistance can be obtained even the magnetization of the ferromagnets are weak and the insulating tunneling barriers are featureless. Our findings provide a new fascinating mechanism to obtain high tunneling magnetoresistance.
description: 9 pages, 6 figures, the title changed, figures and references updated
The Sound of Brands
Creators: name: Nufer, Gerd
name: Moser, Horst
Publisher: name: Universität Tübingen
Year: 2018
Subjects: subject: Marketing , Management
subject: 330
subject: Branding
subject: Audio Branding
subject: Markenmanagement

description: The aim of this research paper is to both examine and conceptualise the concept of audio branding. Audio branding is an important part of the overall brand management concept and corporate identity. Strong brands ease the choice for customers and convey values and a certain quality promise. Branding is of vital importance. It needs to be acknowledged that only 0.004% of all outer stimuli reach the human consciousness. Therefore, audio branding is a way to further strengthen the overall brand awareness. This leads to an emotional connection with a brand. This study strives to determine the characteristics of audio branding and to analyse the corporate audio branding of Audi. The result of this research study is the suggestion of the use of audio branding in a way that fits the overall brand picture. Otherwise, the brand communication is inconsistent, and this could lead to a misunderstanding of the brand values for customers. The analysis of the Audi corporate sound design might be beneficial for practitioners. The overall evaluation of the concept of audio branding contributes to the existing body of literature in branding.
Design and evaluation of large volume transparent plastic containers for water remediation by solar disinfection
Creators: name: Polo-López, MI
name: Martínez-García, A
name: Abeledo-Lameiro, M J
name: Buck, L
name: Marasini, R
name: Marugán, J
name: García-Gil, Á
name: Morse, T
name: Brockliss, S
name: Ferrero, G
name: Lungu, K
name: Teferi, M
name: Asmelash, T
name: Gómez-Couso, H
name: Fernández-Ibáñez, P
name: Dhodapkar, R
name: Sawant, Bhairavi
name: McGuigan, Kevin
Publisher: name: Royal College of Surgeons in Ireland
Year: 2023
Subjects: subject: 90410 Water Treatment Processes
subject: FOS: Chemical engineering

description: Solar water disinfection (SODIS) is a household drinking water treatment with a number of well-known benefits such as simplicity, efficiency, and low cost. It consists of solar exposure of water stored in transparent containers (1-2 L) to direct sunlight for at least 6 hours, producing water that is safe for drinking. During recent years, much effort has been directed by the scientific community to increase the batch volume of treated-water delivered by SODIS with the main objective of reducing the risk of waterborne disease in communities in resource-poor settings. In this context, this chapter reviews the latest research on the evaluation of common and novel materials employed for the design of larger volume transparent containers (> 20 L) to be used for SODIS. The container design and performance of the materials developed are described from different perspectives, including microbial inactivation (bacteria, viruses and protozoan parasites), mathematical modelling of the microbicidal capacity of the container material based on optical characteristics, their lifespan and stability under natural sunlight as well as field experiences for implementation.
title: Added value of acoustic radiation force impulse imaging in breast ultrasound
Creators: name: Kapetas, Panagiotis
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Breast
subject: Ultrasound
subject: Elastography
subject: Biopsy
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Ultrasound (US) of the breast is a valuable adjunct to mammography in the characterization of breast lesions. Using established diagnostic criteria, as described in the BI-RADS lexicon [1], it shows a high sensitivity at a variable but in general...
title: Predicting poor outcome from simple ankle injuries
Creators: name: Bullock, Stuart
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Musculoskeletal soft tissue
subject: Musculoskeletal joint
subject: CT
subject: Ultrasound
subject: Outcomes analysis
subject: Athletic injuries

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Background Ankle injuries are one of the most common presentations to emergency departments, and in the UK has an estimated incidence of 302,000 new cases per year [1]. The outcome of these patients is often unknown and although many go on to a full...
title: Radiation dose and acquisition time for CT transaortic valve implantation (TAVI) planning examinations with new-generation 256 multi-detector CT (MDCT)
Creators: name: Sablayrolles, Jean Louis
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Cardiac
subject: Vascular
subject: Cardiovascular system
subject: CT
subject: CT-Angiography
subject: CT-High Resolution
subject: Comparative studies
subject: Dosimetric comparison

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To evaluate benefits of a new generation 256 MDCT in terms of radiation dose, acquisition time, contrast volume and image quality for transcatheter aortic valve implantation (TAVI)...
title: Stent-retriever thrombectomy of small caliber intracranial vessels using pREset LITE - safety and efficacy
Creators: name: Kurre, Wiebke
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: CNS
subject: Interventional vascular
subject: Emergency
subject: Catheter arteriography
subject: Recanalisation
subject: Embolism / Thrombosis

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Endovascular recanalization of acute intracranial vessel occlusions is a well-established and accepted treatment modality. It´s efficacy was proven in several randomized trials. Target vessels in these trials were largely confined to the proximal...
title: Surprising Transformation of Azulene by Cycloaddition with 1-(Diethylamino)propyne
Creators: name: Hafner, Klaus
name: Lindner, Hans Jörg
name: Ude, Werner
Publisher: name: Wiley
Year: 2023

description: The cyclopentacyclononene derivative (3). the first compound to contain this ring system and also the first stable cyclononatetraene not to have an annelated benzene ring, has been synthesized from the “ethanoazulene” (1). This synthesis is possible because azulene reacts readily with the ynamine (2), to give the tricyclic species (4). Although 4,6,8-methylazulene initially gives the desired ring system (5), immediate transannular bonding occurs. The bracket in (1) prevents this reaction.
How I saved endangered plants fromLarge-scale Projects
Creators: name: 陈, 绪言
name: Gao, Gang
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310801
subject: Phycology (incl. marine grasses)
classificationCode: 310302
subject: Community ecology (excl. invasive species ecology)

description: Before any artificial large-scale engineering project starts, a detailed natural ecological environment impact assessment should be carried out.
Defining Privilege
Creators: name: Schwam, Allison
name: Czopp, Alex
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: The goal of this project is to learn how people define and think of the term "privilege." Also, we are interested in learning about what contributes to different ways of thinking about privilege.
MPEC 2024-R128 : 2019 EG8
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Taking NO for an answer: NO modulation of BMP2 signalling and osteoinduction (English)
Creators: name: Differ, Christopher
Publisher: name: Humboldt-Universität zu Berlin
Year: 2018
Subjects: subject: Bone Morphogenetic Protein 2; BMP2; Stickstoffmonoxid; NO; Inhibitor of Differentiation 1; ID1
subject: Bone Morphogenetic Protein 2; BMP2; Nitric Oxide ; NO; Inhibitor of Differentiation 1; ID1
subject: 570 Biowissenschaften; Biologie
subject: YK 4312
subject: YK 4313
subject: WE 5320

description: Das Bone Morphogenetic Protein 2 (BMP2) gehört zur TGF-beta Superfamilie und findet seinen Fokus in der osteogenen Aktivierung und in der Anwendung bei der Frakturheilung. Es wird angenommen, dass weitere, bisher unbekannte Verbindungen existieren, die die BMP2-Signalübertragung und die osteogene Aktivität verbessern und somit zu einer verbesserten klinischen Wirksamkeit von BMP2 führen. Für den Stickstoffoxid (NO)-Signalweg ist bereits bekannt, dass im endothelialen Kontext eine Verbindung zum BMP2-Signalweg existiert. Ziel dieser Arbeit war es daher, eine Verbindung zwischen dem NO- und BMP2-Signalweg bezüglich der Regulierung des BMP2-abhängigen Signalwegs und der Osteoinduktion aufzuzeigen. Dies erfolgte durch Anwendung von Inhibitoren (LNAME, ODQ und LY83583) und Aktivatoren (L-Arginin, Deta NONOate, SNAP und YC-1) des NO-Signalwegs, in Kombination mit BMP2. Eine mögliche Verbindung zwischen dem BMP2- und NO-Signalweg, über eine Protein Kinase A (PKA) Brücke, wurde durch die Anwendung des PKA Inhibitors H89 untersucht. Zusammenfassend zeigen diese Ergebnisse, dass der NO-Stoffwechselweg den BMP2-vermittelten Signalweg und die osteoinduktive Aktivität modulieren kann, wobei PKA beide Signalwege im Rahmen der BMP Signalübertragung verbindet, jedoch nicht zu einer BMP2-vermittelten Osteoinduktion führt.
description: Bone Morphogenetic Protein 2 (BMP2) is a TGF-beta superfamily member, with a major focus on osteogenic activity and application in fracture healing. In order to improve efficiency of BMP2 in the clinic, it is assumed that additional, yet unknown compounds can improve BMP2 signalling and osteogenic activity. The Nitric Oxide (NO) pathway has previously shown to be connected with the BMP2 pathway in an endothelial context. Therefore, it was the aim of this study to unravel connections between the NO and BMP2 pathway in regulating BMP2 mediated signalling and osteoinduction. This was carried out through the application of inhibitors (LNAME, ODQ and LY83583) and activators (L-Arginine, Deta NONOate, SNAP and YC-1) of the NO pathway in combination with BMP2. A proposed connection between BMP2 and NO pathways via a Protein Kinase A (PKA) bridge was investigated by application of H89 inhibitor. In summary, these results show that the NO pathway can modulate BMP2 mediated signalling and osteoinductive activity. The PKA bridge connects NO and BMP2 only for the process of BMP2 signalling, but not for BMP2 mediated osteoinduction.
The Impact of Code Switching on Understanding Other’s Minds
Creators: name: Johnson, Darin
name: Falk, Emily
name: Mattan, Bradley
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Communication
subject: Linguistics
subject: FOS: Languages and literature
subject: International and Intercultural Communication
subject: Interpersonal and Small Group Communication
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: Code switching is a cultural shifting and coping strategy many Black Americans use to try to establish a sense of belonging as they communicate in different contexts. People most frequently think of code switching as switching between languages or dialects of the same language. Indeed, one example of code switching would be changing from using features of African American Vernacular English to predominantly using features of Standard English when speaking. However, code switching can also happen in non-verbal communication (e.g., altering gestures, affect, and mannerisms). Code switching here is operationalized as referring to the extent to which someone might shift their speech and behavior to align with dominating cultural norms that operate within different spaces. A review of the literature has revealed sparse evidence of any experimentally validated psychometric scales to measure this construct. In this preregistration, we propose a study using an online survey to (1) validate and assess the reliability of a novel code switching measure, adapted from the African American Women Shifting Scale (see Johnson et al., 2016), and (2) Investigate the potential between-participants associations between code switching and individual differences in self-reported mentalizing tendency in Black Americans.
Spontaneous hot-electron light emission from electron-fed optical antennas
Creators: name: Buret, Mickael
name: Uskov, Alexander V.
name: Dellinger, Jean
name: Cazier, Nicolas
name: Mennemanteuil, Marie-Maxime
name: Berthelot, Johann
name: Smetanin, Igor V.
name: Protsenko, Igor E.
name: Colas-des-Francs, Gérard
name: Bouhelier, Alexandre
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Nanoscale electronics and photonics are among the most promising research areas providing functional nano-components for data transfer and signal processing. By adopting metal-based optical antennas as a disruptive technological vehicle, we demonstrate that these two device-generating technologies can be interfaced to create an electronically-driven self-emitting unit. This nanoscale plasmonic transmitter operates by injecting electrons in a contacted tunneling antenna feedgap. Under certain operating conditions, we show that the antenna enters a highly nonlinear regime in which the energy of the emitted photons exceeds the quantum limit imposed by the applied bias. We propose a model based upon the spontaneous emission of hot electrons that correctly reproduces the experimental findings. The electron-fed optical antennas described here are critical devices for interfacing electrons and photons, enabling thus the development of optical transceivers for on-chip wireless broadcasting of information at the nanoscale.
Recombinase-Dependent Mouse Lines for Chemogenetic Activation of Genetically Defined Cell Types
Creators: name: Sciolino, Natale R.
name: Plummer, Nicholas W.
name: McElligott, Zoe A.
name: Robertson, Sabrina D.
name: Chen, Yu-Wei
name: Jensen, Patricia
name: Dudek, Serena M.
name: Alexander, Georgia M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Chemogenetic technologies, including the mutated human Gq-coupled M3 muscarinic receptor (hM3Dq), have greatly facilitated our ability to directly link changes in cellular activity to altered physiology and behavior. Here, we extend the hM3Dq toolkit with recombinase-responsive mouse lines that permit hM3Dq expression in virtually any cell type. These alleles encode a fusion protein designed to increase effective expression levels by concentrating hM3Dq to the cell body and dendrites. To illustrate their broad utility, we targeted three different genetically defined cell populations: noradrenergic neurons of the compact, bilateral locus coeruleus and two dispersed populations, Camk2a+ neurons and GFAP+ glia. In all three populations, we observed reproducible expression and confirmed that activation of hM3Dq is sufficient to dose-dependently evoke phenotypic changes, without extreme phenotypes associated with hM3Dq overexpression. These alleles offer the ability to non-invasively control activity of diverse cell types to uncover their function and dysfunction at any developmental stage.
title: Überraschende Umwandlung von Azulen durch Cycloaddition mit 1-(Diethylamino)propin
Creators: name: Hafner, Klaus
name: Lindner, Hans Jörg
name: Ude, Werner
Publisher: name: Wiley
Year: 2023

description: Das Cyclopentacyclononen-Derivat (3), die erste Verbindung mit diesem Ringsystem und zugleich das erste stabile Cyclononatetraen ohne anellierten Benzolring, wurde aus dem „Ethano-azulen”︁ (1) synthetisiert. Dieser Erfolg ist der Beobachtung zu verdanken, daß Azulen leicht mit dem Inamin (2) reagiert, und zwar zum Tricyclus (4). 4, 6, 8-Trimethylazulen ergibt zwar das gewünschte Ringsystem (5), doch schnürt es sich sofort ab. Die Klammern in (1) verhindert diese Reaktion.
MPEC 2024-R129 : 2016 FX185
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: Automatic assessment of cardiac load due to acute pulmonary embolism: saddle vs. central and peripheral emboli distribution
Creators: name: Aviram, Galit
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Pulmonary vessels
subject: CT-Angiography
subject: Computer Applications-3D
subject: Embolism / Thrombosis

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Computed tomography pulmonary angiography (CTPA) is currently the modality of choice for the diagnosis of acute pulmonary embolism (PE). 1,2 CTPA-based risk stratification of patients with acute PE is an attractive alternative to echocardiography by...
title: Cycled superselective pseudo-continuous Arterial Spin Labeling without the need for acquiring a control image
Creators: name: Lindner, Thomas
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: Professional issues
subject: Vascular
subject: MR
subject: MR-Diffusion/Perfusion
subject: Imaging sequences
subject: Physics

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Territorial Arterial Spin Labeling (ASL) are gaining popularity in advanced magnetic resonance imaging applications. Among different methods, pseudo-continuous ASL appears as the method of choice to obtain information about either the wohle brain or...
Strategic Bidding in an Accumulating Priority Queue: Equilibrium Analysis
Creators: name: Haviv, Moshe
name: Ravner, Liron
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Science and Game Theory (cs.GT)
subject: FOS: Computer and information sciences

description: We study the strategic purchasing of priorities in a time-dependent accumulating priority M/G/$1$ queue. We formulate a non-cooperative game in which customers purchase priority coefficients with the goal of reducing waiting costs in exchange. The priority of each customer in the queue is a linear function of the individual waiting time, with the purchased coefficient being the slope. The unique pure Nash equilibrium is solved explicitly for the case with homogeneous customers. A general characterisation of the Nash equilibrium is provided for the heterogeneous case. It is shown that both avoid the crowd and follow the crowd behaviours are prevalent, within class types and between them. We further present a pricing mechanism that ensures the order of the accumulating priority rates in equilibrium follows a $Cμ$ type rule and improves overall efficiency.
SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase
Creators: name: Lei, Mona
name: Liu, Zhonghua
name: Tian, Yuan
name: Huang, Xun
name: Qi, Yanfei
name: Harris, Thurl E.
name: Sadowski, Pawel
name: Yang, Hongyuan
name: Parton, Robert G.
name: Mak, Hoi Yin
name: Chen, Weiqin
name: Pagac, Martin
name: Liu, George
name: Boroda, Salome
name: Wu, Zengying
name: Lukmantara, Ivan E.
name: Cooper, Daniel E.
name: Kotevski, Damian
name: Ferguson, Charles
name: Du, Ximing
name: Coleman, Rosalind A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Berardinelli-Seip congenital lipodystrophy 2 (BSCL2) is caused by loss-of-function mutations in SEIPIN, a protein implicated in both adipogenesis and lipid droplet expansion but whose molecular function remains obscure. Here, we identify physical and functional interactions between SEIPIN and microsomal isoforms of glycerol-3-phosphate acyltransferase (GPAT) in multiple organisms. Compared to controls, GPAT activity was elevated in SEIPIN-deficient cells and tissues and GPAT kinetic values were altered. Increased GPAT activity appears to underpin the block in adipogenesis and abnormal lipid droplet morphology associated with SEIPIN loss. Overexpression of Gpat3 blocked adipogenesis, and Gpat3 knockdown in SEIPIN-deficient preadipocytes partially restored differentiation. GPAT overexpression in yeast, preadipocytes, and fly salivary glands also formed supersized lipid droplets. Finally, pharmacological inhibition of GPAT in Seipin-/- mouse preadipocytes partially restored adipogenesis. These data identify SEIPIN as an evolutionarily conserved regulator of microsomal GPAT and suggest that GPAT inhibitors might be useful for the treatment of human BSCL2 patients.
The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals
Creators: name: McFadden, Rita-Marie T.
name: Li, Zengshan
name: Brickey, W. June
name: Lund, Pauline Kay
name: Koblansky, A. Alicia
name: Jobin, Christian
name: Liu, Rongrong
name: Ding, Shengli
name: Montgomery, Stephanie A.
name: Hu, Peizhen
name: Wilson, Justin E.
name: Ting, Jenny P.-Y.
name: Mühlbauer, Marcus
name: Truax, Agnieszka D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: NOD-like receptor (NLR) proteins are intracellular innate immune sensors/receptors that regulate immunity. This work shows that NLRX1 serves as a tumor suppressor in colitis-associated cancer (CAC) and sporadic colon cancer by keeping key tumor promoting pathways in check. Nlrx1(-/-) mice were highly susceptible to CAC, showing increases in key cancer-promoting pathways including nuclear factor κB (NF-κB), mitogen-activated protein kinase (MAPK), signal transducer and activator of transcription 3 (STAT3), and interleukin 6 (IL-6). The tumor-suppressive function of NLRX1 originated primarily from the non-hematopoietic compartment. This prompted an analysis of NLRX1 function in the Apc(min/+) genetic model of sporadic gastrointestinal cancer. NLRX1 attenuated Apc(min/+) colon tumorigenesis, cellular proliferation, NF-κB, MAPK, STAT3 activation, and IL-6 levels. Application of anti-interleukin 6 receptor (IL6R) antibody therapy reduced tumor burden, increased survival, and reduced STAT3 activation in Nlrx1(-/-)Apc(min/+) mice. As an important clinical correlate, human colon cancer samples expressed lower levels of NLRX1 than healthy controls in multiple patient cohorts. These data implicate anti-IL6R as a potential personalized therapy for colon cancers with reduced NLRX1.
Does witness credibility depend on the interaction between misinformation type and context (courtroom vs. non-courtroom)?
Creators: name: Lassetter, Bethany
name: Hodges, Sara
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: This registration preregisters a study that investigates whether witness credibility depends on the interaction between misinformation type and context.
MPEC 2024-R130 : 2016 YZ40
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.