cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Augmenting Zero Trust Architecture to Endpoints Using Blockchain: A State-of-The-Art Review
Creators: name: Alevizos, Lampis
name: Ta, Vinh Thong
name: Eiza, Max Hashem
Publisher: name: arXiv
Year: 2021
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: With the purpose of defending against lateral movement in today's borderless networks, Zero Trust Architecture (ZTA) adoption is gaining momentum. With a full scale ZTA implementation, it is unlikely that adversaries will be able to spread through the network starting from a compromised endpoint. However, the already authenticated and authorised session of a compromised endpoint can be leveraged to perform limited, though malicious, activities ultimately rendering the endpoints the Achilles heel of ZTA. To effectively detect such attacks, distributed collaborative intrusion detection systems with an attack scenario-based approach have been developed. Nonetheless, Advanced Persistent Threats (APTs) have demonstrated their ability to bypass this approach with a high success ratio. As a result, adversaries can pass undetected or potentially alter the detection logging mechanisms to achieve a stealthy presence. Recently, blockchain technology has demonstrated solid use cases in the cyber security domain. In this paper, motivated by the convergence of ZTA and blockchain-based intrusion detection and prevention, we examine how ZTA can be augmented onto endpoints. Namely, we perform a state-of-the-art review of ZTA models, real-world architectures with a focus on endpoints, and blockchain-based intrusion detection systems. We discuss the potential of blockchain's immutability fortifying the detection process and identify open challenges as well as potential solutions and future directions.
description: (1) Fixed the reference numbering (2) Fixed syntax errors, improvements (3) document re-structured
Schrödinger equation in a general curved space-time geometry
Creators: name: Exirifard, Qasem
name: Karimi, Ebrahim
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We consider relativistic quantum field theory in the presence of an external electric potential in a general curved space-time geometry. We utilise Fermi coordinates adapted to the time-like geodesic to describe the low-energy physics in the laboratory and calculate the leading correction due to the curvature of the space-time geometry to the Schrödinger equation. We then compute the non-vanishing probability of excitation for a hydrogen atom that falls in or is scattered by a general Schwarzschild black hole. The photon that is emitted from the excited state by spontaneous emission extracts energy from the black hole, increases the decay rate of the black hole and adds to the information paradox.
description: 39 pages, 9 figures, Matches the published version
Espécies arbóreas no horto de plantas medicinais da UFGD beneficiam a saúde humana e atraem a fauna
Creators: name: VIEIRA, M.C.
name: HEREDIA-ZÁRATE, N.A.
name: HEREDIA-VIEIRA, S.C.
name: SANTOS, A.C.T.
name: SANTOS, C.C.
name: SILVA, O.B.
name: PEREIRA, Z.V.
Publisher: name: Zenodo
Year: 2021
Subjects: Schinus terebinthifolia
Campomanesia adamantium
Allophylus edulis
Alibertia edulis
Jacaranda decurrens

description: Descrevem-se as espécies arbóreas existentes no Horto de Plantas Medicinais, da Universidade Federal da Grande Dourados e sua importância medicinal e como atrativo para a fauna (pássaros, borboletas, abelhas e outros)
The contact process in disordered and periodic binary two-dimensional lattices
Creators: name: Fallert, S. V.
name: Kim, Y. M.
name: Neugebauer, C. J.
name: Taraskin, S. N.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The critical behavior of the contact process in disordered and periodic binary 2d-lattices is investigated numerically by means of Monte Carlo simulations as well as via an analytical approximation and standard mean field theory. Phase-separation lines calculated numerically are found to agree well with analytical predictions around the homogeneous point. For the disordered case, values of static scaling exponents obtained via quasi-stationary simulations are found to change with disorder strength. In particular, the finite-size scaling exponent of the density of infected sites approaches a value consistent with the existence of an infinite-randomness fixed point as conjectured before for the 2d disordered CP. At the same time, both dynamical and static scaling exponents are found to coincide with the values established for the homogeneous case thus confirming that the contact process in a heterogeneous environment belongs to the directed percolation universality class.
description: submitted to Physical Review E
Apparatus for real-time acoustic imaging of Rayleigh-Benard convection
Creators: name: Kuehn, Kerry
name: Polfer, Jonathan
name: Furno, Joanna
name: Finke, Nathan
Publisher: name: arXiv
Year: 2007
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We have designed and built an apparatus for real-time acoustic imaging of convective flow patterns in optically opaque fluids. This apparatus takes advantage of recent advances in two-dimensional ultrasound transducer array technology; it employs a modified version of a commercially available ultrasound camera, similar to those employed in non-destructive testing of solids. Images of convection patterns are generated by observing the lateral variation of the temperature dependent speed of sound via refraction of acoustic plane waves passing vertically through the fluid layer. The apparatus has been validated by observing convection rolls in both silicone oil and ferrofluid.
description: 20 pages, 11 figures, submitted to the Review of Scientific Instruments
The likelihood of divorce and the riskiness of financial decisions
Creators: name: Stark, Oded
name: Szczygielski, Krzysztof
Publisher: name: Universität Tübingen
Year: 2019
Subjects: subject: Ehescheidung , Risiko , Wahrscheinlichkeit
subject: 330
subject: Men’s preferences towards risk
subject: Risk-taking behavior
subject: Concern at having low relative wealth
subject: Relative and absolute risk aversion
subject: Marital-based difference in attitudes towards risk
subject: Likelihood of divorce

description: We link causally the riskiness of men’s management of their finances with the probability of their experiencing a divorce. Our point of departure is that when comparing single men to married men, the former manage their finances in a more aggressive (that is, riskier) manner. Assuming that single men believe that low relative wealth has a negative effect on their standing in the marriage market and that they care about their standing in that market more than married men do, we find that a stronger distaste for low relative wealth translates into reduced relative risk aversion and, consequently, into riskier financial behavior. With this relationship in place we show how this difference varies depending on the “background” likelihood of divorce and, hence, on the likelihood of re-entry into the marriage market: married men in environments that are more prone to divorce exhibit risk-taking behavior that is more similar to that of single men than married men in environments that are little prone to divorce. We offer a theoretical contribution that helps inform and interpret empirical observations and regularities and can serve as a guide for follow-up empirical work, having established and identified the direction of causality.
title: Das Geoid aus Beobachtungen der Satellitenaltimetrie
Creators: name: Arnold, Kurt
Publisher: name: Zentralinstitut für Physik der Erde
Year: 1972

description: Es wird eine Theorie für die Störungen der Satellitenbahnen durch das Sohwerepotential der Erde entwickelt; als Parameter des Potentials erscheinen dabei die Geoidundulationen. Im Anschluß daran werden die Fehlergleichungen für die Satellitenaltimetrie aufgestellt, wobei die Höhe des Satelliten über dem Meere direkt beobachtet wird. Zur Darstellung der Details der Geoidundulationen werden Mittelwerte von 1° x 1°-Kompartimenten eingeführt. Die Auflösung des etwa 40 000 Unbekannte umfassenden Normalgleichungssystems wird zurückgeführt auf die Auflösung von 200 Systemen mit jeweils 200 Unbekannten. Gegebenenfalls müssen die Rechnungen iterativ durchgeführt werden. Ferner wird gezeigt, wie man für die Geoidundulationen abschnittsweise analytische Ausdrücke einführen kann, deren Parameter durch die Auflösung zu bestimmen wären, und wie man die Geoidundulationen durch die Schwereanomalien als Parameter ersetzen kann. auf Wachstum und Orientierung untersucht. Die Kristalle wurden mit Hilfe chemischer Transportreaktionen bei 500 °с und Feldstärken von О - 4000 Ое gezüchtet. Magnetfelder dieser Stärke üben auf Wachstum und Orientierung beider Mineralien keinen Einfluß aus. Die experimentellen Ergebnisse werden im Hinblick auf das magnetische Verhalten kleiner Teilchen diskutiert. Dabei zeigt sich, daß die Kristallite bereits fest auf eine Unterlage (Quarzglastrager bzw. Ampullenwand) aufgewachsen sind, wenn sie noch superparamagnetisches Verhalten zeigen.
description: Veröffentlichungen des Zentralinstituts Physik der Erde; 7
Computing modular polynomials in quasi-linear time
Creators: name: Enge, Andreas
Publisher: name: arXiv
Year: 2007
Subjects: subject: Number Theory (math.NT)
subject: Computational Complexity (cs.CC)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: We analyse and compare the complexity of several algorithms for computing modular polynomials. We show that an algorithm relying on floating point evaluation of modular functions and on interpolation, which has received little attention in the literature, has a complexity that is essentially (up to logarithmic factors) linear in the size of the computed polynomials. In particular, it obtains the classical modular polynomials $Φ_\ell$ of prime level $\ell$ in time O (\ell^3 \log^4 \ell \log \log \ell). Besides treating modular polynomials for $Γ^0 (\ell)$, which are an important ingredient in many algorithms dealing with isogenies of elliptic curves, the algorithm is easily adapted to more general situations. Composite levels are handled just as easily as prime levels, as well as polynomials between a modular function and its transform of prime level, such as the Schläfli polynomials and their generalisations. Our distributed implementation of the algorithm confirms the theoretical analysis by computing modular equations of record level around 10000 in less than two weeks on ten processors.
Geschäftsanfall der Gerichte in Thüringen 2004
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Tübingen
Year: 2005
Subjects: subject: Justiz , Thüringen , Statistik
subject: 360

description: Geschäftsanfall, die Geschäftsentwicklung und Angaben zur Rechtsprechung bei den ordentlichen Gerichten, Fachgerichten sowie Staatsanwaltschaften erfasst und aufbereitet. In Thüringen wurden die Geschäftsstatistiken im Bereich der Rechtspflege mit den Familien- und Arbeitsrechtssachen im Jahr 1991 eingeführt. Im Jahr 1993 erfolgte die erstmalige Erhebung der Statistiken im Zivil-, Straf- und Verwaltungsrecht, der Staatsanwaltschaften sowie der Rehabilitierungsverfahren, 1994 die der Finanzgerichtsbarkeit. Alle im vorliegenden Bericht aufgeführten Justizgeschäftstatistiken basieren auf jeweiligen Anordnungen des Thüringer Justizministeriums.
Predicting antimicrobial activity of conjugated oligoelectrolyte molecules via machine learning
Creators: name: Tiihonen, Armi
name: Cox-Vazquez, Sarah J.
name: Liang, Qiaohao
name: Ragab, Mohamed
name: Ren, Zekun
name: Hartono, Noor Titan Putri
name: Liu, Zhe
name: Sun, Shijing
name: Zhou, Cheng
name: Incandela, Nathan C.
name: Limwongyut, Jakkarin
name: Moreland, Alex S.
name: Jayavelu, Senthilnath
name: Bazan, Guillermo C.
name: Buonassisi, Tonio
Publisher: name: arXiv
Year: 2021
Subjects: subject: Applied Physics (physics.app-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: New antibiotics are needed to battle growing antibiotic resistance, but the development process from hit, to lead, and ultimately to a useful drug, takes decades. Although progress in molecular property prediction using machine-learning methods has opened up new pathways for aiding the antibiotics development process, many existing solutions rely on large datasets and finding structural similarities to existing antibiotics. Challenges remain in modelling of unconventional antibiotics classes that are drawing increasing research attention. In response, we developed an antimicrobial activity prediction model for conjugated oligoelectrolyte molecules, a new class of antibiotics that lacks extensive prior structure-activity relationship studies. Our approach enables us to predict minimum inhibitory concentration for E. coli K12, with 21 molecular descriptors selected by recursive elimination from a set of 5,305 descriptors. This predictive model achieves an R2 of 0.65 with no prior knowledge of the underlying mechanism. We find the molecular representation optimum for the domain is the key to good predictions of antimicrobial activity. In the case of conjugated oligoelectrolytes, a representation reflecting the 3-dimensional shape of the molecules is most critical. Although it is demonstrated with a specific example of conjugated oligoelectrolytes, our proposed approach for creating the predictive model can be readily adapted to other novel antibiotic candidate domains.
12 and 18 micron images of dust surrounding HD 32297
Creators: name: Moerchen, Margaret M.
name: Telesco, Charles M.
name: De Buizer, James M.
name: Packham, Christopher
name: Radomski, James T.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the first subarcsecond-resolution images at multiple mid-IR wavelengths of the thermally-emitting dust around the A0 star HD 32297. Our observations with T-ReCS at Gemini South reveal a nearly edge-on resolved disk at both 11.7 microns and 18.3 microns that extends ~150 AU in radius. The mid-IR is the third wavelength region in which this disk has been resolved, following coronagraphic observations by others of the source at optical and near-IR wavelengths. The global mid-IR colors and detailed consideration of the radial color-temperature distribution imply that the central part of the disk out to ~80 AU is relatively deficient in dust.
description: 4 pages, 3 figures; accepted for publication in ApJL
Geschäftsanfall der Gerichte in Thüringen 2006
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Tübingen
Year: 2007
Subjects: subject: Justiz , Thüringen , Statistik
subject: 360

description: Die Justizgeschäftsstatistiken widerspiegeln die Arbeit der Gerichte und Staatsanwaltschaften. Es werden der Geschäftsanfall, die Geschäftsentwicklung und Angaben zur Rechtsprechung bei den ordentlichen Gerichten, Fachgerichten sowie Staatsanwaltschaften erfasst und aufbereitet. In Thüringen wurden die Geschäftsstatistiken im Bereich der Rechtspflege mit den Familien- und Arbeitsrechtssachen im Jahr 1991 eingeführt. Im Jahr 1993 erfolgte die erstmalige Erhebung der Statistiken im Zivil-, Straf- und Verwaltungsrecht, der Staatsanwaltschaften sowie der Rehabilitierungsverfahren, 1994 die der Finanzgerichtsbarkeit. Alle im vorliegenden Bericht aufgeführten Justizgeschäftsstatistiken basieren auf jeweiligen Anordnungen des Thüringer Justizministeriums.
Geschäftsanfall der Gerichte in Thüringen 2007
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Tübingen
Year: 2008
Subjects: subject: Justiz , Thüringen , Statistik
subject: 360

description: Die Justizgeschäftsstatistiken widerspiegeln die Arbeit der Gerichte und Staatsanwaltschaften. Es werden der Geschäftsanfall, die Geschäftsentwicklung und Angaben zur Rechtsprechung bei den ordentlichen Gerichten, Fachgerichten sowie Staatsanwaltschaften erfasst und aufbereitet. In Thüringen wurden die Geschäftsstatistiken im Bereich der Rechtspflege mit den Familien- und Arbeitsrechtssachen im Jahr 1991 eingeführt. Im Jahr 1993 erfolgte die erstmalige Erhebung der Statistiken im Zivil-, Straf- und Verwaltungsrecht, der Staatsanwaltschaften sowie der Rehabilitierungsverfahren, 1994 die der Finanzgerichtsbarkeit. Alle im vorliegenden Bericht aufgeführten Justizgeschäftsstatistiken basieren auf jeweiligen Anordnungen des Thüringer Justizministeriums.
A Ring of Warm Dust in the HD 32297 Debris Disk
Creators: name: Fitzgerald, Michael P.
name: Kalas, Paul G.
name: Graham, James R.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the detection of a ring of warm dust in the edge-on disk surrounding HD 32297 with the Gemini-N/MICHELLE mid-infrared imager. Our N'-band image shows elongated structure consistent with the orientation of the scattered-light disk. The Fnu(11.2 um) = 49.9+/-2.1 mJy flux is significantly above the 28.2+/-0.6 mJy photosphere. Subtraction of the stellar point spread function reveals a bilobed structure with peaks 0.5"-0.6" from the star. An analysis of the stellar component of the SED suggests a spectral type later than A0, in contrast to commonly cited literature values. We fit three-dimensional, single-size grain models of an optically thin dust ring to our image and the SED using a Markov chain Monte Carlo algorithm in a Bayesian framework. The best-fit effective grain sizes are submicron, suggesting the same dust population is responsible for the bulk of the scattered light. The inner boundary of the warm dust is located 0.5"-0.7" (~65 AU) from the star, which is approximately cospatial with the outer boundary of the scattered-light asymmetry inward of 0.5". The addition of a separate component of larger, cooler grains that provide a portion of the 60 um flux improves both the fidelity of the model fit and consistency with the slopes of the scattered-light brightness profiles. Previous indirect estimates of the stellar age (~30 Myr) indicate the dust is composed of debris. The peak vertical optical depths in our models (~0.3-1 x 1e-2) imply that grain-grain collisions likely play a significant role in dust dynamics and evolution. Submicron grains can survive radiation pressure blow-out if they are icy and porous. Similarly, the inferred warm temperatures (130-200 K) suggest that ice sublimation may play a role in truncating the inner disk.
description: ApJ accepted, 8 pages, 4 figures
Gamified Solution to the Right of Education - Edulearn19
Creators: name: Turkawka, Gregory
Publisher: name: Zenodo
Year: 2019
Subjects: LMS
Learning Record Store
LRS
OER
SDG-4
AI
Blockchain
Digital ID
DID
Certificates
xAPI
Batches
Matching-System
Achievement Maps
Gamification
PLE
PLN

description: Presentation of a "Gamified Solution to the Right of Education" at edulearn19.
Semantics in Multi-objective Genetic Programming
Creators: name: Galván, Edgar
name: Trujillo, Leonardo
name: Stapleton, Fergal
Publisher: name: arXiv
Year: 2021
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: Semantics has become a key topic of research in Genetic Programming (GP). Semantics refers to the outputs (behaviour) of a GP individual when this is run on a data set. The majority of works that focus on semantic diversity in single-objective GP indicates that it is highly beneficial in evolutionary search. Surprisingly, there is minuscule research conducted in semantics in Multi-objective GP (MOGP). In this work we make a leap beyond our understanding of semantics in MOGP and propose SDO: Semantic-based Distance as an additional criteriOn. This naturally encourages semantic diversity in MOGP. To do so, we find a pivot in the less dense region of the first Pareto front (most promising front). This is then used to compute a distance between the pivot and every individual in the population. The resulting distance is then used as an additional criterion to be optimised to favour semantic diversity. We also use two other semantic-based methods as baselines, called Semantic Similarity-based Crossover and Semantic-based Crowding Distance. Furthermore, we also use the NSGA-II and the SPEA2 for comparison too. We use highly unbalanced binary classification problems and consistently show how our proposed SDO approach produces more non-dominated solutions and better diversity, leading to better statistically significant results, using the hypervolume results as evaluation measure, compared to the rest of the other four methods.
description: 30 pages, 4 figures, 10 tables, journal article
What Happens to Apparent Horizons in a Binary Black Hole Merger?
Creators: name: Pook-Kolb, Daniel
name: Hennigar, Robie A.
name: Booth, Ivan
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We resolve the fate of the two original apparent horizons during the head-on merger of two non-spinning black holes. We show that following the appearance of the outer common horizon and subsequent inter-penetration of the original horizons, they continue to exist for a finite period of time before they are individually annihilated by unstable MOTSs. The inner common horizon vanishes in a similar, though independent, way. This completes the understanding of the analogue of the event horizon's "pair of pants" diagram for the apparent horizon. Our result is facilitated by a new method for locating marginally outer trapped surfaces (MOTSs) based on a generalized shooting method. We also discuss the role played by the MOTS stability operator in discerning which among a multitude of MOTSs should be considered as black hole boundaries.
description: 6 pages, 5 figures, V2: final version with several changes (including changed title)
Soft-collinear effects in prompt photon production
Creators: name: Basu, Rahul
name: Laenen, Eric
name: Misra, Anuradha
name: Motylinski, Patrick
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We extend next-to-leading logarithmic threshold and joint resummation for prompt photon production to include leading collinear effects. The impact of these effects is assessed for both fixed-target and collider kinematics. We find them in general to be small, but noticeable.
description: 14 pages, 12 figures, added comment on fragmentation contribution and one more reference. Version to appear in Phys. Rev. D
Theory of Parity Violated Cooper Pairs in Weakly Noncentrosymmetric Superconductors
Creators: name: Fujimoto, Satoshi
Publisher: name: arXiv
Year: 2007
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We propose that in noncentrosymmetric superconductors with weakly asymmetric spin-orbit interaction the field-induced pair correlation between the spin-orbit split different bands ignored in previous studies yields unique effects; i.e. the Pauli depairing effect is anisotropic in the momentum space, and as a result, magnetic fields induce point-node-like anisotropic gap structure of the quasiparticle energy even for isotropic s-wave states, which seriously affects thermodynamic quantities at low temperatures. Also, it is shown that when the magnitude of the spin-orbit interaction is smaller than the superconducting gap, the specific heat as a function of a magnetic field exhibit a two-gap-like behavior, even when there is only a single gap. These features characterize parity violated Cooper pairs in weakly noncentrosymmetric systems. We suggest the possible detection of these effects in the superconductor with weakly broken inversion symmetry Y_2C_3.
description: 10 pages, 4 figures
Exact fuzzy sphere thermodynamics in matrix quantum mechanics
Creators: name: Kawahara, Naoyuki
name: Nishimura, Jun
name: Takeuchi, Shingo
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We study thermodynamical properties of a fuzzy sphere in matrix quantum mechanics of the BFSS type including the Chern-Simons term. Various quantities are calculated to all orders in perturbation theory exploiting the one-loop saturation of the effective action in the large-N limit. The fuzzy sphere becomes unstable at sufficiently strong coupling, and the critical point is obtained explicitly as a function of the temperature. The whole phase diagram is investigated by Monte Carlo simulation. Above the critical point, we obtain perfect agreement with the all order results. In the region below the critical point, which is not accessible by perturbation theory, we observe the Hagedorn transition. In the high temperature limit our model is equivalent to a totally reduced model, and the relationship to previously known results is clarified.
description: 22 pages, 14 figures, (v2) some typos corrected
KLF17 promotes human naïve pluripotency but is not required for its establishment.
Creators: name: Lea, Rebecca A
name: McCarthy, Afshan
name: Boeing, Stefan
name: Fallesen, Todd
name: Elder, Kay
name: Snell, Phil
name: Christie, Leila
name: Adkins, Sarah
name: Shaikly, Valerie
name: Taranissi, Mohamed
name: Niakan, Kathy K
Publisher: name: The Francis Crick Institute
Year: 2021
Subjects: Imaging
Tumour Biology
Gene Expression
Genetics & Genomics
Developmental Biology
Genome Integrity & Repair
Chemical Biology & High Throughput
Computational & Systems Biology

description: Current knowledge of the transcriptional regulation of human pluripotency is incomplete, with lack of inter-species conservation observed. Single-cell transcriptomics analysis of human embryos previously enabled us to identify transcription factors, including the zinc-finger protein KLF17, that are enriched in the human epiblast and naïve hESCs. Here we show that KLF17 is expressed coincident with the known pluripotency-associated factors NANOG and SOX2 across human blastocyst development. We investigate the function of KLF17 using primed and naïve hESCs for gain- and loss-of-function analyses. We find that ectopic expression of KLF17 in primed hESCs is sufficient to induce a naïve-like transcriptome and that KLF17 can drive transgene-mediated resetting to naïve pluripotency. This implies a role for KLF17 in establishing naïve pluripotency. However, CRISPR-Cas9-mediated knockout studies reveal that KLF17 is not required for naïve pluripotency acquisition in vitro. Transcriptome analysis of naïve hESCs identifies subtle effects on metabolism and signalling pathways following KLF17 loss-of-function, and possible redundancy with other KLF paralogues. Overall, we show that KLF17 is sufficient, but not necessary, for naïve pluripotency under the given in vitro conditions.
A renormalization group study of the dynamics of active membranes: universality classes and scaling laws
Creators: name: Cagnetta, Francesco
name: Skultety, Viktor
name: Evans, Martin R.
name: Marenduzzo, Davide
Publisher: name: arXiv
Year: 2021
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Motivated by experimental observations of patterning at the leading edge of motile eukaryotic cells, we introduce a general model for the dynamics of nearly-flat fluid membranes driven from within by an ensemble of activators. We include, in particular, a kinematic coupling between activator density and membrane slope which generically arises whenever the membrane has a non-vanishing normal speed. We unveil the phase diagram of the model by means of a perturbative field-theoretical renormalization group analysis. Due to the aforementioned kinematic coupling the natural dynamical scaling is acoustic, that is the dynamical critical exponent is 1. However, as soon as the the normal velocity of the membrane is tuned to zero, the system crosses over to diffusive dynamic scaling in mean field. Distinct critical points can be reached depending on how the limit of vanishing velocity is realised: in each of them corrections to scaling due to nonlinear coupling terms must be taken into accounts. The detailed analysis of these critical points reveals novel scaling regimes wich can be accessed with perturbative methods, together with signs of strong coupling behaviour, which establishes a promising ground for further non-perturbative calculations. Our results unify several previous studies on the dynamics of active membrane, while also identifying nontrivial scaling regimes which cannot be captured by passive theories of fluctuating interfaces and are relevant for the physics of living membranes.
Comment to the paper "Radiation induced by relativistic electrons propagating through random layered stacks: Numerical simulation results" by A.A.Varfolomeev and et al NIM B 256,705 (2007)
Creators: name: Gevorkian, Zh. S.
name: Verhoeven, J.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: We show that the numerical code used in the above mentioned paper does not take into account the multiple scattering effects of electromagnetic field properly and is therefore incorrect.
description: 2pages,submitted to NIM B
Perturbative SO(10) GUT and the Minimal Higgs Sector
Creators: name: Wiesenfeldt, Soren
name: Willenbrock, Scott
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The breaking of SO(10) to SU(3)_C x U(1)_EM can be accomplished by just four Higgs fields: the symmetric rank-two tensor, S(54); a pair of spinors, C(16) and Cbar(16bar); and a vector, T(10). This setup is also able to generate realistic fermion masses. The heavy color triplets in the vector and spinor fields mediate proton decay via dimension-five operators. The experimental bounds on proton decay constrain the structure and size of the Yukawa operators.
description: v2: discussion about gauge coupling unification extended; figure added; to appear in Phys. Lett. B
The building up of the disk galaxy M33 and the evolution of the metallicity gradient
Creators: name: Magrini, Laura
name: Corbelli, Edvige
name: Galli, Daniele
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The evolution of radial gradients of metallicity in disk galaxies and its relation with the disk formation are not well understood. Theoretical models of galactic chemical evolution make contrasting predictions about the time evolution of metallicity gradients. To test chemical evolution models and trace the star formation and accretion history of low luminosity disk galaxies we focus on the Local Group galaxy M33. We analyze O/H and S/H abundances in planetary nebulae, H{\sc ii} regions, and young stars, together with known [Fe/H] abundances in the old stellar population of M33. With a theoretical model, we follow the time evolution of gas (diffuse and condensed in clouds), stars, and chemical abundances in the disk of M33, assuming that the galaxy is accreting gas from an external reservoir. Our model is able to reproduce the available observational constraints on the distribution of gas and stars in M33 and to predict the time evolution of several chemical abundances. In particular, we find that a model characterized by a continuous infall of gas on the disk, at a rate of $\dot M_{\rm inf}\approx 1$ $M_\odot$ yr$^{-1}$, almost constant with time, can also account for the relatively high rate of star formation and for the shallow chemical gradients. Supported by a large sample of high resolution observations for this nearby galaxy, we conclude that the metallicity in the disk of M33 has increased with time at all radii, with a continuous flattening of the gradient over the last $\sim 8$ Gyr.
description: 16 pages, 11 figures, A&A accepted
Pulse Profiles, Spectra and Polarization Characteristics of Non-Thermal Emissions from the Crab-Like Pulsars
Creators: name: Takata, J.
name: Chang, H. -K.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We discuss non-thermal emission mechanism of the Crab-like pulsars with both a two-dimensional electrodynamical study and a three-dimensional model. We investigate the emission process in the outer gap accelerator. In the two-dimensional electrodynamical study, we solve the Poisson equation of the accelerating electric field in the outer gap and the equation of motion of the primary particles with the synchrotron and the curvature radiation process and the pair-creation process. We show a solved gap structure which produces a consistent gamma-ray spectrum with EGRET observation. Based on the two-dimensional model, we conduct a three-dimensional emission model to calculate the synchrotron and the inverse-Compton processes of the secondary pairs produced outside the outer gap. We calculate the pulse profiles, the phase-resolved spectra and the polarization characteristics in optical to $γ$-ray bands to compare the observation of the Crab pulsar and PSR B0540-69. For the Crab pulsar, we find that the outer gap geometry extending from near the stellar surface to near the light cylinder produces a complex morphology change of the pulse profiles as a function of the photon energy. This predicted morphology change is quite similar with that of the observations. The calculated phase-resolved spectra are consistent with the data through optical to the $γ$-ray bands. We demonstrate that the 10$\sim$20 % of the polarization degree in the optical emissions from the Crab pulsar and the Vela pulsar are explained by the synchrotron emissions with the particle gyration motion.
description: 39 pages, 11 figures, Accepted for publication in ApJ
The Ionization Fraction of Barnard 68: Implications for Star and Planet Formation
Creators: name: Maret, Sebastien
name: Bergin, Edwin A.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a detailed study of the ionization fraction of the Barnard 68 pre-stellar core, using millimeter H13CO+ and DCO+ lines observations. These observations are compared to the predictions of a radiative transfer model coupled to a chemical network that includes depletion on grains and gas phase deuterium fractionation. Together with previous observations and modelling of CO and isotopologues, our H13CO+ and DCO+ observations and modelling allow to place constraints on the metal abundance and the cosmic ionization rate. The H13CO+ emission is well reproduced for metals abundances lower than 3e-9 and a standard cosmic ray ionization rate. However, the observations are also consistent with a complete depletion of metals, i.e. with cosmic rays as the only source of ionization at visual extinctions greater than a few Av . The DCO+ emission is found to be dependent of the ortho to para H2 ratio, and indicates a ratio of ~1e-2. The derived ionization fraction is about 5e-9 with respect to H nuclei, which is about an order of magnitude lower than the one observed in the L1544 core. The corresponding ambipolar diffusion timescale is found to be an order of magnitude larger than the free fall timescale at the center of the core. The inferred metal abundance suggests that magnetically inactive regions (dead zones) are present in protostellar disks.
description: To appear in the Astrophysical Journal
Learning and memory of chemosensory stimuli by underyearling coho salmon Oncorhynchus kisutch (Walbaum)
Creators: name: Courtenay, Simon Charles
Publisher: name: University of British Columbia
Year: 2010

description: This study addressed the hypothesis that coho salmon (Oncorhynchus kisutch) learn and remember the odours of their natal environment. During one or more of the embryo, alevin and early fry (first 14 d) stages, fish were exposed to the artificial odorant morpholine, natural odorants generated by conspecifics, or creek water. After an interval of at least 1 month the preference of fry for an odorant was tested in a Y-maze and compared to that of naive fry. Increased preference was interpreted as recognition. Fish exposed during any or all of the embryo, alevin, or early fry stages showed greater preference for morpholine than naive fish when tested 54-125 d after exposure. In addition, previously exposed fish responded to morpholine with greater heart rate reduction (another measure of recognition) than naive fish in tests 477-532 d after exposure. Exposure to the odour of similarly-aged members of another family of the same population during the alevin stage, and to that of a second family during the early fry stage resulted in increased preference for the alevin-stage odour by one of four test groups, for the fry-stage odour by another group, and for both odours by a third group, in Y-maze tests conducted at least 32 d after exposure. Subsequent experiments revealed preference to be an insensitive measure of recognition because it is greatly influenced by odour concentration and possibly other odour characteristics which differ between families. Members of the Quinsam River population exposed throughout the embryo, alevin, and early fry stages to the odour of similarly-aged members either the Big Qualicum River or Puntledge River populations each preferred the familiar odour when tested 69-79 d after exposure. In addition to familiarity, preference among population-odours was found to be influenced by quantity of odour. Quinsam, Big Qualicum, and Puntledge fish each preferred water conditioned by faeces of members of their own population over blank water and in one of two experiments over water conditioned by faeces of non-population members, suggesting that at least some of the odorants mediating intraspecific discriminations are present in faeces. Exposure to creek water for a 1 month period centered around swimup did not result in greater preference than that shown by naive fish for creek water over well water or either of two river waters in tests performed at least 58 d after exposure. It is concluded that coho form long-term memories of at least some artificial and natural odours in early life and that learning is not restricted to a brief critical period of development.
MICS Asia Phase II - Sensitivity to the aerosol module
Creators: name: Sartelet, Karine
name: Hayami, Hiroshi
name: Sportisse, Bruno
Publisher: name: arXiv
Year: 2007
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: FOS: Physical sciences

description: In the framework of the model inter-comparison study - Asia Phase II (MICS2), where eight models are compared over East Asia, this paper studies the influence of different parameterizations used in the aerosol module on the aerosol concentrations of sulfate and nitrate in PM10. An intracomparison of aerosol concentrations is done for March 2001 using different configurations of the aerosol module of one of the model used for the intercomparison. Single modifications of a reference setup for model configurations are performed and compared to a reference case. These modifications concern the size distribution, i.e. the number of sections, and physical processes, i.e. coagulation, condensation/evaporation, cloud chemistry, heterogeneous reactions and sea-salt emissions. Comparing monthly averaged concentrations at different stations, the importance of each parameterization is first assessed. It is found that sulfate concentrations are little sensitive to sea-salt emissions and to whether condensation is computed dynamically or by assuming thermodynamic equilibrium. Nitrate concentrations are little sensitive to cloud chemistry. However, a very high sensitivity to heterogeneous reactions is observed. Thereafter, the variability of the aerosol concentrations to the use of different chemistry transport models (CTMs) and the variability to the use of different parameterizations in the aerosol module are compared. For sulfate, the variability to the use of different parameterizations in the aerosol module is lower than the variability to the use of different CTMs. However, for nitrate, for monthly averaged concentrations averaged over four stations, these two variabilities have the same order of magnitude.
description: Atmospheric Environment (2007) in press
Molecular reconstruction of recurrent evolutionary switching in olfactory receptor specificity.
Creators: name: Prieto-Godino, Lucia L
name: Schmidt, Hayden R
name: Benton, Richard
Publisher: name: The Francis Crick Institute
Year: 2021
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Imaging
subject: Genetics & Genomics
subject: Developmental Biology
subject: Ecology,Evolution & Ethology

description: Olfactory receptor repertoires exhibit remarkable functional diversity, but how these proteins have evolved is poorly understood. Through analysis of extant and ancestrally-reconstructed drosophilid olfactory receptors from the Ionotropic receptor (Ir) family, we investigated evolution of two organic acid-sensing receptors, Ir75a and Ir75b. Despite their low amino acid identity, we identify a common 'hotspot' in their ligand-binding pocket that has a major effect on changing the specificity of both Irs, as well as at least two distinct functional transitions in Ir75a during evolution. Moreover, we show that odor specificity is refined by changes in additional, receptor-specific sites, including those outside the ligand-binding pocket. Our work reveals how a core, common determinant of ligand-tuning acts within epistatic and allosteric networks of substitutions to lead to functional evolution of olfactory receptors.
Ethical Research Assessment With Contributor Roles
Creators: name: Hosseini, Mohammad
name: Holmes, Kristi
Publisher: name: Zenodo
Year: 2021
Subjects: DORA
Research Assessment
Contributor Roles
Ethics

description: This poster provides a snapshot of the application of contributor roles for the implementation of DORA recommendations. By highlighting how contributor roles could benefit various stakeholders (e.g., universities and scientific institutions, funding agencies, publishers, organizations that supply metrics, and individual researchers), this poster will help extend the debate about contributor roles.
GRB 050410 and GRB 050412: are they really dark GRBs?
Creators: name: Mineo, T.
name: Mangano, V.
name: Covino, S.
name: Cusumano, G.
name: La Parola, V.
name: Troja, E.
name: Roming, P.
name: Burrows, D. N.
name: Campana, S.
name: Capalbi, M.
name: Chincarini, G.
name: Gehrels, N.
name: Giommi, P.
name: Hill, J. E.
name: Marshall, F.
name: Moretti, A.
name: O'Brien, P.
name: Page, M.
name: Perri, M.
name: Romano, P.
name: Sbarufatti, B.
name: Sato, G.
name: Tagliaferri, G.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a detailed analysis of the prompt and afterglow emission of GRB 050410 and GRB 050412 detected by Swift for which no optical counterpart was observed. The 15-150 keV energy distribution of the GRB 050410 prompt emission shows a peak energy at 53 keV. The XRT light curve of this GRB decays as a power law with a slope of alpha=1.06+/-0.04. The spectrum is well reproduced by an absorbed power law with a spectral index Gamma_x=2.4+/-0.4 and a low energy absorption N_H=4(+3;-2)x10^21 cm^(-2) which is higher than the Galactic value. The 15-150 keV prompt emission in GRB 050412 is modelled with a hard (Gamma=0.7+/-0.2) power law. The XRT light curve follows a broken power law with the first slope alpha_1=0.7+/-0.4, the break time T_break=254(-41;+79) s and the second slope alpha_2=2.8(-0.8;+0.5). The spectrum is fitted by a power law with spectral index Gamma_x=1.3+/-0.2 which is absorbed at low energies by the Galactic column. The GRB 050410 afterglow reveals the expected characteristics of the third component of the canonical Swift light curve. Conversely, a complex phenomenology was detected in the GRB 050412 because of the presence of the very early break. The light curve in this case can be interpreted as being the last peak of the prompt emission. The two bursts present tight upper limits for the optical emission, however, neither of them can be clearly classified as dark. For GRB 050410, the suppression of the optical afterglow could be attributed to a low density interstellar medium surrounding the burst. For GRB 050412, the evaluation of the darkness is more difficult due to the ambiguity in the extrapolation of the X-ray afterglow light curve.
description: 6 figures, 9 pages, accepted for publication in A&A
Degradation kinetics and mechanism of 3-Chlorobenzoic acid in anoxic water environment using graphene/TiO2 as photocatalyst
Creators: name: Huang, Yiyang
name: Wang, Hui
name: Huang, Kai
name: Huang, Donggen
name: Yin, Shuang
name: Guo, Qin
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Degradation kinetics and mechanism of 3-Chlorobenzoic acid (3-CBA) in anoxic water environment using graphene/TiO2 (GR/TiO2) as photocatalyst had been investigated. The effects of various parameters such as catalyst dosage, pH, initial concentration, catalyst reuse and dissolved oxygen (DO) on 3-CBA photocatalytic degradation kinetics were studied. The qualitative and quantitative analysis for degradation intermediate products and parent compound were studied by using HPLC, HPLC/MS/MS and IC technologies. The results show that the residual concentration of 3-CBA has a good linear relationship and its correlation coefficient R2 are all greater than 0.985 by Langmuir–Hinshelwood (L–H) dynamic model under different photocatalytic degradation conditions. Some oxidative degradation products such as 3-chlorophenol, resorcinol, and hydroxyquinol are generated, and some reductive degradation products such as 3-chlorobenzaldehyde, 3-hydroxybenzaldehyde, 3-hydroxybenzyl alcohol, and cyclohexanediol are produced, and part of 3-CBA are mineralized to generate CO2 when DO is in the range of 0.5–1.0 mg/L; When DO is less than 0.28 mg/L, photocatalytic reduction mainly occurs. The results provide a theoretical basis for photocatalytic in situ remediation of pollutants in anoxic water environment.