cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A Microfinance Model of Insurable Covariate Risk and Endogenous Effort
Creators: name: Dougherty, John
name: Miranda, Mario
name: Dougherty, John
name: Miranda, Mario
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agricultural and Food Policy
subject: International Development
subject: Microfinance
subject: Index Insurance
subject: Moral Hazard
subject: Endogenous Effort

description: Previous literature suggests that weather based index insurance has the potential to greatly benefit poor rural households that are exposed to significant sources of systemic risk. This study proposes a simple model of how providing index insurance may reduce moral hazard problems inherent in microfinance contracts. Through increasing the value of the dynamic incentive of repayment, the model demonstrates that providing index insurance can increase endogenous effort choice, particularly for joint liability loans, provided that insurance premiums are sufficiently low.
Probing the dark ages with redshift distribution of GRBs
Creators: name: Choudhury, T. Roy
name: Srianand, R.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In this article, we explore the possibility of using the properties of gamma ray bursts (GRBs) to probe the physical conditions in the epochs prior to reionization. The redshift distribution of GRBs is modelled using the Press-Schechter formalism with an assumption that they follow the cosmic star formation history. We reproduce the observed star formation rate obtained from galaxies in the redshift range 0 < z < 5, as well as the redshift distribution of the GRBs inferred from the luminosity-variability correlation of the burst light curve. We show that the fraction of GRBs at high redshifts, whose afterglows cannot be observed in R and I band due to HI Gunn Peterson optical depth can, at the most, account for one third of the dark GRBs. The observed redshift distribution of GRBs, with much less scatter than the one available today, can put stringent constraints on the epoch of reionization and the nature of gas cooling in the epochs prior to reionization.
description: 5 pages. Revised following referee's comments. Accepted in MNRAS Letters (pink pages)
The Development of New Treatments for Multi-Drug Resistant Tuberculosis
Creators: name: LISA BARBARO
Publisher: name: Monash University
Year: 2019
Subjects: subject: 30499 Medicinal and Biomolecular Chemistry not elsewhere classified
subject: FOS: Chemical sciences
subject: Organic Chemistry

description: New treatments against tuberculosis are urgently needed due to the rise in drug-resistance. This thesis detailed the synthesis of new drugs with potent activity against tuberculosis, which may potentially have an improved safety profile in comparison to the currently used therapies.
A proof of unlimited multistability for phosphorylation cycles
Creators: name: Feliu, Elisenda
name: Rendall, Alan D.
name: Wiuf, Carsten
Publisher: name: arXiv
Year: 2019
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Dynamical Systems (math.DS)
subject: FOS: Biological sciences
subject: FOS: Mathematics

description: The multiple futile cycle is a phosphorylation system in which a molecular substrate might be phosphorylated sequentially n times by means of an enzymatic mechanism. The system has been studied mathematically using reaction network theory and ordinary differential equations. It is known that the system might have at least as many as 2[n/2]+1 steady states (where [x] is the integer part of x) for particular choices of parameters. Furthermore, for the simple and dual futile cycles (n=1,2) the stability of the steady states has been determined in the sense that the only steady state of the simple futile cycle is globally stable, while there exist parameter values for which the dual futile cycle admits two asymptotically stable and one unstable steady state. For general n, evidence that the possible number of asymptotically stable steady states increases with $n$ has been given, which has led to the conjecture that parameter values can be chosen such that [n/2]+1 out of 2[n/2]+1 steady states are asymptotically stable and the remaining steady states are unstable. We prove this conjecture here by first reducing the system to a smaller one, for which we find a choice of parameter values that give rise to a unique steady state with multiplicity 2[n/2]+1. Using arguments from geometric singular perturbation theory, and a detailed analysis of the centre manifold of this steady state, we achieve the desired result.
Initiation and dynamics of hemifusion in lipid bilayers
Creators: name: Hed, Guy
name: Safran, S. A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: One approach to the understanding of fusion in cells and model membranes involves stalk formation and expansion of the hemifusion diaphragm. We predict theoretically the initiation of hemifusion by stalk expansion and the dynamics of mesoscopic hemifusion diaphragm expansion in the light of recent experiments and theory that suggested that hemifusion is driven by intra-membrane tension far from the fusion zone. Our predictions include a square root scaling of the hemifusion zone size on time as well as an estimate of the minimal tension for initiation of hemifusion. While a minimal amount of pressure is evidently needed for stalk formation, it is not necessarily required for stalk expansion. The energy required for tension induced fusion is much smaller than that required for pressure driven fusion.
The Work of Instructors for New Socialist Countryside Construction
Creators: name: ZENG, Lin
name: LU, Shunsheng
name: YANG, Lamei
name: ZHANG, Chaozhong
name: SONG, Yunfei
name: LIU, Yan
name: WU, Zhengyin
name: TAO, Jiajin
name: WU, Guixian
name: ZENG, Lin
name: LU, Shunsheng
name: YANG, Lamei
name: ZHANG, Chaozhong
name: SONG, Yunfei
name: LIU, Yan
name: WU, Zhengyin
name: TAO, Jiajin
name: WU, Guixian
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agribusiness
subject: New countryside construction
subject: Instructors' working practices
subject: Recommendations

description: To meet the wishes and demands of the majority of farmers, it is necessary to steadily build a new socialist countryside, and actively promote urban-rural integration. With the guidance for new countryside construction as an opportunity, this paper studies and explores the working practice of new countryside construction instructors sent by Longyang Agricultural Technique Extension Station for various village committees (or offices) during 2007-2013. This paper analyzes and summarizes the results achieved and the main problems, and puts forth the corresponding recommendations. The results of the analysis can provide a reference for the instructors to carry out the guiding work for new countryside construction.
Supporting Information -Essential oil composition of leaves and biological activities from Psidium myrtoides O. Berg (araçá-roxo)
Creators: name: Renieidy Dias
name: FRANCISCO JOSE TORRES DE AQUINO
name: Nascimento, Evandro Afonso Do
name: Morais, Sergio
name: Cunha, Luis Carlos Scalon
name: Martins, Carlos Henrique Gomes
name: Silva, Claudio Vieira Da
name: Mylla Spirandelli
name: Freitas, Guilherme
name: Lima, Carla Ferreira
name: Joao Matias Souza
Publisher: name: figshare
Year: 2019
Subjects: subject: 30502 Natural Products Chemistry
subject: FOS: Chemical sciences

description: The higher yield (1.4± 0.08%) was for the volatile oil from rainy season. The major compounds from both seasons were trans-caryophyllene (26%) and α-humuleno (15%), for dry season; 18% and 14% for rainy season, respectively). The compounds trans-caryophyllene and trans-caryophyllene oxide presented remarkable changes in concentration in function of the seasonal variation. The essential oil presented bactericidal activity (mainly against Streptococcus sanguinis), and fungicidal activity (mainly against Candida glabrata). The rainy volatile oils were most effective on the promastigotes forms of L. amazonensis (31.8 ± 5.74 μg mL-1) while the dry volatile oils were most effective on Trypanosoma cruzi (54±5.25 μg mL-1). The fresh leaves essential oil from the rainy season (FLRS-EO) presented the higher selectivity against the trypomastigote forms studied. The fresh leaves essential oil from the rainy season (FLRS-EO) presented the higher selectivity against the trypomastigote forms studied.The essential oils of P. myrtoides contain recognized bioactive compounds that could be used as a potential alternative against neglected tropical diseases.
Spectral Distribution in the Eigenvalues Sequence of Products of g-Toeplitz Structures
Creators: name: Ngondiep, Eric
Publisher: name: arXiv
Year: 2019
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65F10, 15A18, 47B36, 47B65

description: Starting from the definition of an $n\times n$ $g$-Toeplitz matrix, $T_{n,g}(u)=\left[\widehat{u}_{r-gs}\right]_{r,s=0}^{n-1},$ where $g$ is a given nonnegative parameter, $\{\widehat{u}_{k}\}$ is the sequence of Fourier coefficients of the Lebesgue integrable function $u$ defined over the domain $\mathbb{T}=(-π,π]$, we consider the product of $g$-Toeplitz sequences of matrices, $\{T_{n,g}(f_{1})T_{n,g}(f_{2})\},$ which extends the product of Toeplitz structures, $\{T_{n}(f_{1})T_{n}(f_{2})\},$ in the case where the symbols $f_{1},f_{2}\in L^{\infty}(\mathbb{T}).$ Under suitable assumptions, the spectral distribution in the eigenvalues sequence is completely characterized for the products of $g$-Toeplitz structures. Specifically, for $g\geq2$ our result shows that the sequences $\{T_{n,g}(f_{1})T_{n,g}(f_{2})\}$ are clustered to zero. This extends the well-known result, which concerns the classical case (that is, $g=1$) of products of Toeplitz matrices. Finally, a large set of numerical examples confirming the theoretic analysis is presented and discussed.
description: 28 pages, 16 tables
Quantum group symmetry in sine-Gordon and affine Toda field theories on the half-line
Creators: name: Delius, Gustav W
name: MacKay, Niall J.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Quantum Algebra (math.QA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We consider the sine-Gordon and affine Toda field theories on the half-line with classically integrable boundary conditions, and show that in the quantum theory a remnant survives of the bulk quantized affine algebra symmetry generated by non-local charges. The paper also develops a general framework for obtaining solutions of the reflection equation by solving an intertwining property for representations of certain coideal subalgebras of quantized affine algebras.
description: AMSLatex, 20 pages. Typos corrected and reference added. To appear in Commun. Math. Phys
In silico design novel Vibsanin B derivatives as inhibitor for heat shock protein 90 based on 3D-QSAR, molecular docking and molecular dynamics simulation
Creators: name: Qingxiu He
name: Chu, Han
name: Yuxuan Wang
name: Haiqiong Guo
name: Yuanqiang Wang
name: Siyi Wang
name: Zhiwei Feng
name: Xie, Xiang-Qun
name: Hu, Yong
name: Haibin Liu
name: Zhihua Lin
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: The heat shock protein 90 (Hsp90) involves in many physiological functions, especially oncogenesis, development, and metabolism. Hsp90 inhibitors have shown therapeutic potential for cancer. In the present work, we first constructed 3D-QSAR models for 41 ViB derivatives using CoMFA and CoMSIA. The CoMFA (q2 = 0.591, r2 = 0.985) and CoMSIA (q2 = 0.602, r2 = 0.996) model showed good stability and predictability. Then the counter maps were created to depict the contribution of function groups for activity of compounds, which was described as steric, hydrophobic, and hydrogen bond force fields. Sequentially, We docked all inhibitors to the active site of Hsp90 which is the amino acids around 0.5 Å of the crystallographic ligand Cdc37 to explore their binding mode through molecular docking method. The interaction between Hsp90 and inhibitors showed that several hydrogen bonds and hydrophobic interactions played an important role in their recognition. Importantly, we virtually designed eight novel inhibitor analogues based on 3D-QSAR models, counter maps, and the binding features. Finally, molecular docking was used to obtain the stable conformation of Hsp90 complexed with these small molecules, and molecular dynamics (MD) simulation was carried out to further investigate the dynamics interactions. Our results showed that the virtually designed compounds could bind to the key residues of Hsp90, including Met93, Asn101, and Thr104, which meant these compounds had potential activity. In addition, the theoretically predicted ADME/T profile was conducted, and the results indicated that the designed inhibitors showed fairly pharmacokinetics properties. All these results could provide clues for design and modification of novel inhibitors of Hsp90.
The Cluster Substructure - Alignment Connection
Creators: name: Plionis, Manolis
Publisher: name: arXiv
Year: 2001
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Using the APM cluster data we investigate whether the dynamical status of clusters is related to the large-scale structure of the Universe. We find that cluster substructure is strongly correlated with the tendency of clusters to be aligned with their nearest neighbour and in general with the nearby clusters that belong to the same supercluster. Furthermore, dynamically young clusters are more clustered than the overall cluster population. These are strong indications that cluster develop in a hierarchical fashion by anisotropy merging along the large-scale filamentary superclusters within which they are embedded.
description: To appear in the Proceedings of `Galaxy Clusters and the High Redshift Universe Observed in X-rays', XXIth Moriond Astrophysics Meeting (March 2001), Eds. Doris Neumann et al
Vegetation dynamics in the face of a major land-use change: a 30-year case study from semi-arid South Africa
Creators: name: Hyvärinen, Olli
name: M Timm Hoffman
name: Chevonne Reynolds
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Plant Biology

description: Although wildlife production is widely considered beneficial for semi-arid environments, few studies have reported on the long-term environmental effects of converting from livestock production to game ranching. Asante Sana Game Reserve in South Africa was stocked with domestic livestock for centuries. However, after 1996 game ranching was adopted in the reserve. We investigated the long-term (1987–2017) spatial and temporal change in vegetation productivity and type on the reserve using Landsat multispectral data and soil adjusted vegetation index (SAVI), and explored the relationship between changes in vegetation productivity and the potential drivers. The results show that while Thicket has decreased overall, it has expanded into parts of Grassland and Shrubland, and Bare-ground has expanded into parts of Shrubland and Thicket. Overall vegetation productivity increased over time, with the greatest increases in Thicket and Grazing lawn and the lowest in Shrubland and Bare-ground. Changes in rainfall, fire and stocking rates were all significant predictors of the observed changes in vegetation productivity, but rainfall had the strongest effect. This research highlights some of the complex responses that arise in semi-arid vegetation when domestic livestock production is replaced by game ranching, and points towards key issues that can be addressed by management.
Research on the Brand Construction of Agritourism Enterprise in Chongqing
Creators: name: YANG, Yurong
name: YANG, Yurong
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agribusiness
subject: Agritourism
subject: Brand building
subject: Industrial integration

description: Agritourism is a modern agricultural model, which is combination of agriculture and rural tourism. Its goal is to carry on the culture of farming and achieve economic efficiency. To achieve this goal, brand building is very important. However, most companies have the same goods and services in the development process. Managers lack brand awareness, and enterprises lack core competitiveness. To solve these problems, the agritourism enterprises must change their management concepts, establish brand awareness, improve quality of service, increase the cultural connotation of products and services, and strengthen marketing efforts to achieve the overall improvement of modern agricultural brand.
Low-cost Wireless Condition Monitoring for an Ultracold Atom Machine
Creators: name: Chilcott, Matthew
name: Kjærgaard, Niels
Publisher: name: arXiv
Year: 2019
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We present a flexible wireless monitoring system forbcondition-based maintenance and diagnostics tailored for dynamic and complex experimental setups encountered in modern research laboratories. Our platform leverages an Internet-of-Things approach to monitor a wide range of physical parameters via wireless sensor modules that broadcast to a networked computer. We give a specific demonstration for a so-called ultracold atom machine, which is the workhorse of many emerging quantum technologies and marries a broad spectrum of equipment and instrumentation into its setup. As a distinctive feature, our monitoring system taps into physical parameters of the ultracold atom machine both via customized sensor modules that directly perform measurements, and via modules that recruit and annex constituent instruments of the machine for the additional purpose of retrieving information for diagnostics.
description: Real-time dashboard at: http://hoodoo.otago.ac.nz/mattlab
Munidopsis lignaria Williams & Baba 1989
Creators: name: Wicksten, Mary K.
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Galatheidae
Munidopsis
Munidopsis lignaria

description: Munidopsis lignaria Williams & Baba, 1989
(Fig. 35I, J)
 Munidopsis ciliata: Ambler 1980: 19, fig. 4. [Not M. ciliata Wood-Mason, 1891, Indo-West Pacific species].
 Munidopsis lignaria Williams & Baba, 1989: 904, figs. 2f, 4.
 Diagnosis (after Williams & Baba 1989). Rostrum narrowly triangular, exceeding eyestalk by its own or slightly greater length, without lateral spines. Eyes with ovate corneae. Front of carapace with slightly hooked antennal spine lateral to eyestalk followed by concavity ending in small, acute anterolateral angle. Gastric region bearing short setose rugosities behind strong gastric spine at either side of midline, secondary spine lateral to each large spine. Anterior branchial region with less prominent rugosities, lateral margin with strong anterior tooth followed by 4 spines successively smaller in size. Posterior branchial region with moderately developed spine at anterolateral corner, with distinct, transverse rugae. Posterior margin shallowly concave preceded by raised submarginal rim. Abdomen without spines but somites 2, 3 with bold transverse ridges. Chelipeds stout, subequal, with variable rugosities tending to be arranged in longitudinal tracts, ischium with short lateral spine, merus with 3 principal mesial spine, 1 distodorsal spine, distoventral spine, carpus with row of 3 mesiodorsal spines, palm nearly spooned, fingers spooned at apices. Pereopods 2–4 rather long, each merus with crest on dorsal margin ending in distal spine. Carpi with longitudinal spiny dorsal, tuberculate dorsolateral crests, each ending in spine; each propodus slender, with dorsal crest with 2 remote proximal spines, dactyls slender, with row of 10–12 movable spines on flexor margin. Carapace length 6.5–11.6 mm (excluding rostrum).
 Color in life. Not reported.
 Habitat and depth. In association with sunken wood, deep sea basins, 2020–2875 m.
 Range. Cascadia Basin off Oregon, 44˚ 39.8' N, 12˚ 36.4 ' W (type locality) to East Pacific Rise off south central Mexico, 11˚ 52' N, 103˚ 51' W.
 Remarks. The craylet can have wood fragments in its stomach contents.
description: Published as part of Wicksten, Mary K., 2012, Decapod Crustacea of the Californian and Oregonian Zoogeographic Provinces 3371, pp. 1-307 in Zootaxa 3371 on page 152
Disordered Bose-Einstein condensate in hard walls trap
Creators: name: Acosta-Diaz, R.
name: Zarro, C. A. D.
name: Krein, G.
name: Saldivar, A.
name: Svaiter, N. F.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss the effects of quenched disorder in a dilute Bose-Einstein condensate confined in a hard walls trap. Starting from the disordered Gross-Pitaevskii functional, we obtain a representation for the quenched free energy as a series of integer moments of the partition function. Positive and negative disorder-dependent effective coupling constants appear in the integer moments. Going beyond the mean-field approximation, we compute the static two-point correlation functions at first-order in the positive effective coupling constants. We obtain the combined contributions of effects due to boundary conditions and disorder in this weakly disordered condensate. The ground state renormalized density profile of the condensate is presented. We also discuss the appearance of metastable and true ground states for strong disorder, when the effective coupling constants become negative.
description: 10 pages, no figures
Pachycheles holosericus Schmitt 1921
Creators: name: Wicksten, Mary K.
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Porcellanidae
Pachycheles
Pachycheles holosericus

description: Pachycheles holosericus Schmitt, 1921
(Fig. 36B)
 Pachycheles holosericus Schmitt, 1921: 177, pl. 33, fig. 3. — Haig 1960: 173, pl. 34, fig. 2. — Haig et al. 1970: 23. — Haig & Abbott 1980: 589, fig. 24.21.
 Diagnosis. Front narrow, trilobate in frontal view, with tuft of plumose setae. Carapace about as long as broad, strongly convex from front to back, plicate on posterolateral regions. Chelipeds unequal. Merus rugose, granular, anterior margin with strongly projecting granular lobe. Carpus with broad lobe on anterior margin, edged with large granules, rest of surface covered by small granules largely concealed by thick setae. Chelae with large coarse granules, upper surface covered with short plumose setae; fingers gaping in major cheliped; gape in major cheliped with tuft of plumose setae. All segments of pereopods 2–4 with long plumose setae. Telson of abdomen with 5 plates. Carapace length to 18mm.
 Color in life. Body dull brown (Haig & Abbott 1980).
 Habitat and depth. Under rocks, on pier pilings and in sheltered places such as kelp holdfasts and in cavities in sponges, intertidal zone to 18 m.
 Range. Santa Barbara, California to Magdalena Bay, Baja California, Mexico. Type locality Venice, California. There have been no reports of the crab from its type locality since its original description.
 Remarks. Haig & Abbott (1980) reported that these crabs are typically are found in pairs.
description: Published as part of Wicksten, Mary K., 2012, Decapod Crustacea of the Californian and Oregonian Zoogeographic Provinces 3371, pp. 1-307 in Zootaxa 3371 on page 154
title: Pump Design and Development for an Intra-Ventricular Balloon Pump
Creators: name: Sing, Taylor R
Publisher: name: Griffith University
Year: 2024
Subjects: subject: heart failure
subject: mock circulatory loop
subject: left ventricular assist device

description: Heart failure is a growing epidemic within the global population, with an estimated 64.3 million people living with the condition as of 2017, with up to 45% of patients dying within a year of their first hospital admission. For the most severely affected patients, a heart transplant is considered to be the preferred method of treatment. However, there is a scarcity of hearts available for treating each patient that presents, with transplant waiting lists growing year-on-year. In order to combat this, mechanical alternatives to the natural heart, such as ventricular assist devices, total artificial hearts and extra-corporeal membrane oxygenation, have been developed to relieve the patient burden on the healthcare system. The cost of these devices, however, remains high and often treatment exhibits a poor economic case, particularly for short-term support periods. As a result of this, development of a lower-cost alternative device is paramount to improve cost-effectiveness within healthcare for severe heart failure. In previous decades, one of the most prevalent devices was the Intra-Aortic Balloon Pump (IABP), which saw relative success due to being easy to insert, low development and equipment costs and increased accessibility in comparison to other mechanical circulatory support devices. It acts as a volume-displacement device inside of the patient's aorta, inflating during diastole (the heart's relaxation period) to increase circulatory energy. However, the low haemodynamic support provided by IABP and lack of randomized controlled trial evidence suggesting significant patient benefit, has seen its use decline across the past decade. Throughout the timeline of IABP usage, a number of attempts have been made to translate the balloon volume-displacement concept into a device that pumps blood from inside of the ventricle, known as an Intra-Ventricular Balloon Pump (IVBP). Each of these studies demonstrated successful increases in cardiac output and arterial pressure resulting from IVBP; however, the concept never progressed beyond early prototyping and evaluation. No specific reasoning was provided for these previous cessations in research; however, the concept is once again the subject of fresh interest, with as many as four research groups publishing on the concept since 2018. This present study aimed to continue the development of an IVBP prototype device for use as short-term mechanical circulatory support. A primary focus was placed onto evaluating physiological compatibility of the IVBP to provide beneficial support for the patient, with a view to evaluation of risk of mitral valve regurgitation, haemolysis, thrombosis and arrythmia. It was hypothesised that the usage of IVBP would increase the amount of support provided to the circulation without inducing excessive haemolysis and thrombosis, and without induction of mitral valve prolapse, leading to regurgitation. [...]
Determination of Ascorbic Acid in Pharmaceuticals and Biological Fluids by the Quenching of Europium Luminescence
Creators: name: E. J. Llorent-Martínez
name: M. I. Soler-Gallardo
name: M. P. Fernández-Poyatos
name: A. Ruiz-Medina
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Here we present a novel strategy for the quantification of ascorbic acid (AA) (vitamin C). The developed method is based on the quenching effect produced by AA on the time-resolved luminescence signal of europium ions using excitation and emission wavelengths of 388 nm and 617 nm. The method presents a linear dynamic range from 0.2 to 2 µg mL−1 with a detection limit of 0.06 µg mL−1 and a relative standard deviation lower than 6%. The method was applied to the determination of AA in pharmaceutical preparations, human serum and human urine. The obtained results in pharmaceuticals were compared with a reference method; the recovery yields were close to 100% in all cases. The accuracy of the method was statistically assessed, demonstrating the suitability of this alternative method for the determination of AA in pharmaceuticals and biological samples, requiring no sample treatment except for a dilution step.
Nonparametric Tests of the Causal Null With Nondiscrete Exposures
Creators: name: Westling, Ted
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: In many scientific studies, it is of interest to determine whether an exposure has a causal effect on an outcome. In observational studies, this is a challenging task due to the presence of confounding variables that affect both the exposure and the outcome. Many methods have been developed to test for the presence of a causal effect when all such confounding variables are observed and when the exposure of interest is discrete. In this article, we propose a class of nonparametric tests of the null hypothesis that there is no average causal effect of an arbitrary univariate exposure on an outcome in the presence of observed confounding. Our tests apply to discrete, continuous, and mixed discrete-continuous exposures. We demonstrate that our proposed tests are doubly robust consistent, that they have correct asymptotic Type I error if both nuisance parameters involved in the problem are estimated at fast enough rates, and that they have power to detect local alternatives approaching the null at the raten−1/2. We study the performance of our tests in numerical studies, and use them to test for the presence of a causal effect of BMI on immune response in early phase vaccine trials. Supplementary materials for this article are available online.
Small Energy Gap Revealed in CrBr3 by Scanning Tunneling Spectroscopy
Creators: name: Baral, Dinesh
name: Fu, Zhuangen
name: Zadorozhnyi, Andrei S.
name: Dulal, Rabindra
name: Wang, Aaron
name: Shrestha, Narendra
name: Erugu, Uppalaiah
name: Tang, Jinke
name: Dahnovsky, Yuri
name: Tian, Jifa
name: Chien, TeYu
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: CrBr$_{3}$ is a layered van der Waals material with magnetic ordering down to the 2D limit. For decades, based on optical measurements, it is believed that the energy gap of CrBr$_{3}$ is in the range of 1.68-2.1 eV. However, controversial results have indicated that the band gap of CrBr$_{3}$ is possibly smaller than that. An unambiguous determination of the energy gap is critical to the correct interpretations of the experimental results of CrBr$_{3}$. Here, we present the scanning tunneling microscopy and spectroscopy (STM/S) results of CrBr$_{3}$ thin and thick flakes exfoliated onto pyropytic graphite (HOPG) surfaces and density functional theory (DFT) calculations to reveal the small energy gap (peak-to-peak energy gap to be 0.57 eV $\pm$ 0.04 eV; or the onset signal energy gap to be 0.29 $\pm$ 0.05 eV from dI/dV spectra). Atomic resolution topography images show the defect-free crystal structure and the dI/dV spectra exhibit multiple peak features measured at 77 K. The conduction band - valence band peak pairs in the multi-peak dI/dV spectrum agree very well with all reported optical transitions. STM topography images of mono- and bi-layer CrBr$_{3}$ flakes exhibit edge degradation due to short air exposure (~15 min) during sample transfer. The unambiguously determined small energy gap settles the controversy and is the key in better understanding CrBr$_{3}$ and similar materials.
The BeppoSAX High Energy Large Area Survey HELLAS, II: Number counts and X-ray spectral properties
Creators: name: Fiore, F.
name: Giommi, P.
name: Vignali, C.
name: Comastri, A.
name: Matt, G.
name: Perola, G. C.
name: La Franca, F.
name: Molendi, S.
name: Tamburelli, F.
name: Antonelli, L. A.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The BeppoSAX High Energy Large Area Survey (HELLAS) has surveyed about 85 deg^2 of sky in the 5-10 keV band down to a flux of 4-5 10^-14 erg cm-2 s-1. The source surface density of 16.9+-6.4 deg$^{-2}$ at the survey limit corresponds to a resolved fraction of the 5-10 keV X-ray background (XRB) of the order of 20-30 %. Hardness ratios analysis indicates that the spectra of a substantial fraction of the HELLAS sources (at least one third) are harder than a alpha_E = 0.6 power law. This hardness may be due to large absorbing columns. The hardness ratio analysis also indicates that many HELLAS sources may have a spectrum more complex than a single absorbed power law. A soft component, superimposed to a strongly cut-off power law, is likely to be present in several sources.
description: to appear in MNRAS
Munidopsis quadrata Faxon 1893
Creators: name: Wicksten, Mary K.
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Galatheidae
Munidopsis
Munidopsis quadrata

description: Munidopsis quadrata Faxon, 1893
(Fig. 35K)
 Munidopsis quadrata Faxon, 1893: 188; 1895: 97, pl. 23, fig. 1. — Rathbun 1904: 167. — Schmitt 1921: 170, fig. 109. — Pereyra & Alton 1972: 450. — Hart 1982: 170, fig. 67. — Wicksten 1989b: 315. — Hendrickx & Harvey 1999: 376. — Hendrickx 2003b: 25.
 Diagnosis (modified from Hart 1982). Rostrum more or less flat, triangular. Carapace rectangular, without prominent spines but covered with granules. Chelipeds setose, armed with thorn-like spines. Pereopods 2 –4 with smll spines on merus, carpus; dactyls with spinules along flexor margin. Abdominal somites 2–4 with median teeth. Carapace length to 15.5 mm.
 Color in life. Carapace pinkish tan. Rostrum pink, white. Chelipeds mostly white, basis orange, ischium pink. Pereopods 2–4 white, pale tan. Abdomen pinkish with white (Hart 1982).
 Habitat and depth. Mud and sand, 86–1572 m. Most records are from deeper than 900 m.
 Range. Queen Charlotte Is., British Columbia to off Cape Corrientes, Mexico. Type localities off Cape Corrientes (Albatross sta. 3424, 21˚ 15' N, 106˚ 23' W and sta. 3425, 21˚ 19' N 106˚ 24' W).
description: Published as part of Wicksten, Mary K., 2012, Decapod Crustacea of the Californian and Oregonian Zoogeographic Provinces 3371, pp. 1-307 in Zootaxa 3371 on page 152
Dark-Halo Cusp: Asymptotic Convergence
Creators: name: Dekel, Avishai
name: Arad, Itai
name: Devor, Jonathan
name: Birnboim, Yuval
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We propose a model for how the buildup of dark halos by merging satellites produces a characteristic inner cusp, of a density profile ρ\prop r^-a with a -> a_as > 1, as seen in cosmological N-body simulations of hierarchical clustering scenarios. Dekel, Devor & Hetzroni (2003) argue that a flat core of a<1 exerts tidal compression which prevents local deposit of satellite material; the satellite sinks intact into the halo center thus causing a rapid steepening to a>1. Using merger N-body simulations, we learn that this cusp is stable under a sequence of mergers, and derive a practical tidal mass-transfer recipe in regions where the local slope of the halo profile is a>1. According to this recipe, the ratio of mean densities of halo and initial satellite within the tidal radius equals a given function psi(a), which is significantly smaller than unity (compared to being 1 according to crude resonance criteria) and is a decreasing function of a. This decrease makes the tidal mass transfer relatively more efficient at larger a, which means steepening when a is small and flattening when a is large, thus causing converges to a stable solution. Given this mass-transfer recipe, linear perturbation analysis, supported by toy simulations, shows that a sequence of cosmological mergers with homologous satellites slowly leads to a fixed-point cusp with an asymptotic slope a_as>1. The slope depends only weakly on the fluctuation power spectrum, in agreement with cosmological simulations. During a long interim period the profile has an NFW-like shape, with a cusp of 1
description: 37 pages, Latex, aastex.cls, revised, ApJ, 588, in press
Processing Information by Punctuated Spin Superradiance
Creators: name: Yukalov, V. I.
name: Yukalova, E. P.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: The possibility of realizing the regime of punctuated spin superradiance is advanced. In this regime, the number of superradiant pulses and the temporal intervals between them can be regulated. This makes it feasible to compose a kind of the Morse Code alphabet and, hence, to develop a technique of processing information.
description: 6 pages, Revtex, 3 figures
Munidopsis verrilli Benedict 1902
Creators: name: Wicksten, Mary K.
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Galatheidae
Munidopsis
Munidopsis verrilli

description: Munidopsis verrilli Benedict, 1902
(Fig. 36A)
 Munidopsis verrilli Benedict, 1902: 291, fig. 34. — Schmitt 1921: 169, fig. 108. — Goodwin 1952: 395. — Wicksten 1989b: 316.
 Diagnosis. Rostrum slender, triangular, without lateral spines. Front of carapace angled 45˚ from base of rostrum to anterolateral margin, with sharp spine just posterolateral to eye, lateral margin with 4 spines, surface rough, with low tubercles, two spines on gastric region. Chelipeds relatively short, with sharp thorn-like spines on merus, carpus, two spines on palm of chela, fingers relatively short,stout. Pereopods 2–4 with sharp spines on merus, carpus; propodus unarmed, dactyls slender. Abdomen without spines. Carapace length 17 mm.
 Color in life. Carapace iridescent.
 Habitat and depth. Continental slope, 1253–1986 m.
 Range. Oregon to off Cedros I., Baja California, Mexico. Type locality off San Diego (Albatross station 2923).
description: Published as part of Wicksten, Mary K., 2012, Decapod Crustacea of the Californian and Oregonian Zoogeographic Provinces 3371, pp. 1-307 in Zootaxa 3371 on page 153
Hitchin-Kobayashi correspondence, quivers, and vortices
Creators: name: Álvarez-Cónsul, Luis
name: García-Prada, Oscar
Publisher: name: arXiv
Year: 2001
Subjects: subject: Differential Geometry (math.DG)
subject: High Energy Physics - Theory (hep-th)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 58C25 (Primary), 58A30, 53C12, 53C55, 83C05 (Secondary)

description: A twisted quiver bundle is a set of holomorphic vector bundles over a complex manifold, labelled by the vertices of a quiver, linked by a set of morphisms twisted by a fixed collection of holomorphic vector bundles, labelled by the arrows. When the manifold is Kaelher, quiver bundles admit natural gauge-theoretic equations, which unify many known equations for bundles with extra structure. In this paper we prove a Hitchin--Kobayashi correspondence for twisted quiver bundles over a compact Kaehler manifold, relating the existence of solutions to the gauge equations to a stability criterion, and consider its application to a number of situations related to Higgs bundles and dimensional reductions of the Hermitian--Einstein equations.
description: 28 pages; larger introduction, added references for the introduction, added a short comment in Section 1, typos corrected, accepted in Comm. Math. Phys
In silico identification of potential phytochemical inhibitors targeting farnesyl diphosphate synthase of cotton bollworm (Helicoverpa armigera)
Creators: name: Alam, Md Shahid
name: Sharma, Monica
name: Kumar, Rakesh
name: Das, Joy
name: Rode, Surabhi
name: Kumar, Pravindra
name: Prasad, Ramasare
name: Sharma, Ashwani Kumar
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Helicoverpa armigera (Ha), a polyphagous pest, causes significant damage to several crop plants, including cotton. The control of this cosmopolitan pest is largely challenging due to the development of resistance to existing management practices. The Juvenile Hormone (JH) plays a pivotal role in the life cycle of insects by regulating their morphogenetic and gonadotropic development. Hence, enzymes involved in JH biosynthesis are an attractive target for the development of selective insecticides. Farnesyl diphosphate synthase (FPPS), a member protein of (E)-prenyl-transferases, is one of the most crucial enzymes in the biosynthetic pathway of JHs. It catalyzes the condensation of isopentenyl diphosphate (IPP) with dimethylallyl diphosphate (DMAPP), forming farnesyl diphosphate (FPP), a precursor of JH. The study was designed to identify an effective small inhibitory molecule that could inhibit the activity of Helicoverpa armigera – FPPS (HaFPPS) for an effective pest control intervention. Therefore, a 3D model of FPPS protein was generated using homology modeling. The FooDB database library of small molecules was selected for virtual screening, following which binding affinities were evaluated using docking studies. Three top-scored molecules were analyzed for various pharmacophore properties. Further, molecular dynamics (MD) simulation analysis showed that the identified molecules (mitraphylline-ZINC1607834, chlorogenic acid-ZINC2138728 and llagate-ZINC3872446) had a reasonably acceptable binding affinity for HaFPPS and resulted in the formation of a stable HaFPPS-inhibitor(s) complex. The identified phytochemical molecules may be used as potent inhibitors of HaFPPS thus, paving the way for further developing environment-friendly insect growth regulator(s). Communicated by Ramaswamy H. Sarma
The BeppoSAX High Energy Large Area Survey HELLAS, III: testing synthesis models for the X-ray background
Creators: name: Comastri, A.
name: Fiore, F.
name: Vignali, C.
name: Matt, G.
name: Perola, G. C.
name: La Franca, F.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The BeppoSAX High Energy Large Area Survey (HELLAS) has surveyed several tens of square degrees of the sky in the 5--10 keV band down to a flux of about 5 10^-14 erg cm-2 s-1. The extrapolation of the HELLAS logN--logS towards fainter fluxes with an euclidean slope is consistent with the first XMM measurements, in the same energy band, which are a factor 20 more sensitive. The source counts in the hardest band so far surveyed by X-ray satellites are used to constrain XRB models. It is shown that in order to reproduce the 5--10 keV counts over the range of fluxes covered by BeppoSAX and XMM a large fraction of highly absorbed (logN_H = 23--24 cm-2), luminous (L_X > 10^44 erg s-1) AGN is needed. A sizeable number of more heavily obscured, Compton thick, objects cannot be ruled out but it is not required by the present data. The model predicts an absorption distribution consistent with that found from the hardness ratios analysis of the so far identified HELLAS sources. Interestingly enough, there is evidence of a decoupling between X-ray absorption and optical reddening indicators especially at high redshifts/luminosities where several broad line quasars show hardness ratios typical of absorbed power law models with logN_H=22--24 cm-2.
description: to appear in MNRAS
Research on Compensation Mechanism of Land Acquisition in Rural Areas Based on the Practice of Anhui Province
Creators: name: ZHOU, Huixian
name: YU, Zhongxiang
name: ZHOU, Huixian
name: YU, Zhongxiang
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agribusiness
subject: Land acquisition
subject: Compensation mechanism
subject: Perfection

description: With the continuous development of Chinese economy and rapid progress it has made, land demand for urban construction becomes larger and larger. Rural urbanization has a great relation to common prosperity and plays a key role in realizing the 21st century great dream of Chinese people of all ethnic groups. Because of the complicated situation of land acquisition and compensation mechanism, we will conduct a systematic analysis on the compensation mechanism of land acquisition in Anhui Province and put forward the compensation methods to perfect the compensation mechanism according to the present compensation mechanism and the existing shortages of land acquisition in Anhui Province.
A Study on the Value Change of Land Ecosystem Services in Huangguoshu Scenic Area
Creators: name: CHEN, Xiaozhu
name: CHEN, Xiaozhu
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agribusiness
subject: Land use
subject: Value of ecosystem services
subject: Huangguoshu scenic area

description: Land use and ecological service influence and constrain each other and the quantitative research on the value change of ecosystem services and land use in Huangguoshu scenic area can help to provide a scientific basis for the harmonious development of special ecology, society and economy in Huangguoshu scenic area. This paper analyzes the value change of land ecosystem services in Huangguoshu scenic area during 2009-2012, and explores important issues and focus in the land planning and development of Huangguoshu scenic area. The results show that the value of woodland ecosystem services is highest in Huangguoshu scenic area, accounting for nearly 70% of the total value, and there was a slight decline in the total value of ecosystem services in Huangguoshu scenic area during the four years, mainly due to the internal restructuring of agriculture and expansion of construction land. In the future development of Huangguoshu scenic area, it is necessary to economically and intensively use construction land, pay attention to the maintenance and improvement of land ecological environment, and focus on the protection of woodland, pasture land and other types of ecological land, so as to improve the overall regional land ecosystem services.
Additional file 1 of Risk factors for central venous catheter-associated deep venous thrombosis in pediatric critical care settings identified by fusion model
Creators: name: Li, Haomin
name: Lu, Yang
name: Zeng, Xian
name: Feng, Yuqing
name: Fu, Cangcang
name: Duan, Huilong
name: Shu, Qiang
name: Zhu, Jihua
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Cell Biology
Biotechnology
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 1.