title: Study of the adaptation memory and mechanisms of retinal cones
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ ÑÐµÐ½Ð¾Ð¼ÐµÐ½Ð° Ð°Ð´Ð°Ð¿ÑÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ Ð¿Ð°Ð¼ÑÑÐ¸ Ð¸ Ð¼ÐµÑ Ð°Ð½Ð¸Ð·Ð¼Ð¾Ð² Ð°Ð´Ð°Ð¿ÑÐ°ÑÐ¸Ð¸ ÐºÐ¾Ð»Ð±Ð¾ÑÐµÐº ÑÐµÑÑÐ°ÑÐºÐ¸
Creators: name: ÐÐµÐºÑÐ°ÑÐ¾Ð²Ð°, ÐÐ°ÑÐ¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2023
Subjects: ÐÐ¸Ð¾ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ñ
Ð¿Ð°Ð»Ð¾ÑÐºÐ°
ÐºÐ¾Ð»Ð±Ð¾ÑÐºÐ°
ÑÐ¾ÑÐ¾ÑÑÐ°Ð½ÑÐ´ÑÐºÑÐ¸Ñ
ÑÐ²ÐµÑÐ¾Ð²Ð°Ñ Ð°Ð´Ð°Ð¿ÑÐ°ÑÐ¸Ñ
Ð°Ð´Ð°Ð¿ÑÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ Ð¿Ð°Ð¼ÑÑÑ
ÑÐµÐ¼Ð½Ð¾Ð²Ð°Ñ Ð°Ð´Ð°Ð¿ÑÐ°ÑÐ¸Ñ
rod
cone
phototransduction
light adaptation
adaptation memory
dark adaptation

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description: This work is devoted to the study of the post-adaptation dynamics of responses to light stimuli of both isolated cones and cone responses of a retinal fragment in order to test for the presence in them of the phenomenon of "adaptation memory" previously found in rods. By recording the current of single photoreceptors using a suction pipette and ex vivo electroretinography, data were obtained on the dynamics of the response amplitudes of single cones and cones in the retina, demonstrating the presence of a gradual recovery of sensitivity after switching off the adaptive background. The method of ex vivo electroretinography turned out to be more adequate for this study. The results of this work show that cones, under conditions when they have the opportunity to regenerate visual pigment after an adaptive background, indeed repeat the dynamics of the "adaptation memory" mechanism, but demonstrate slower kinetics than rods. This, although contradicting the original expectations of faster kinetics due to the ability of cones to more efficient light adaptation, nevertheless may indicate that different mechanisms lie behind the same phenomenon in closely related photoreceptors.