cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Polymer-Shell Bonded Phase for Improving Online LC-MS Analysis of Intact Proteins, mAbs, and ADCs
Creators: name: Chen, Tse-Hong
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Analytical chemistry not elsewhere classified

description: LC-MS of protein drugs requires new ideas in bonded phase design rather than adapting bonded phases from the realm of small-molecule drugs. The polymer-shell bonded phase is designed to interact with larger molecules and to shield proteins from the silica substrate. The particles consist of a core of solid silica and a shell of dense polymer brush. The polymer layer is thick enough to protect the protein from interactions with silanols to reduce peak tailing. The polymer contains multiple functional groups that introduce more selectivity. This design gives unprecedented LC resolution and MS sensitivity. Our group has developed polymer shell bonded phases for hydrophobic interaction chromatography (HIC-MS) of antibody-drug conjugates (ADCs), hydrophilic interaction liquid chromatography (HILIC-MS) of glycoproteins, and reversed-phase liquid chromatography (RPLC-MS) of monoclonal antibodies. Since HIC is not in-line compatible with MS due to the high salt levels, it is laborious to identify the constituents of HIC peaks. An MS-compatible alternative to HIC is reported here: native reversed phase liquid chromatography (nRPLC). This employs a mobile phase 50 mM ammonium acetate for high sensitivity in MS, and elution with a gradient of water/isopropanol. The nRPLC-MS data show that all ADC species, ranging from drug-to-antibody ratios of 1 to 8, remained intact and native on the column. As we adapt this concept to intact proteins, we find that lysozyme and α-chymotrypsinogen A are both eluted in their native conformations. We also use the polymer-shell concept to resolve IgG1 free thiol variants by RPLC-MS with 0.5% formic acid. Since there are always other variants besides the intended ones, the need for high MS sensitivity is desired to distinguish subtle mass change between disulfide bond and free thiols. Overall, MS sensitivity increases 10X relative while all of the thiol variants are well resolved by the polymethylmethacrylate bonded phase.
online supplementary file 1 - Supplemental material for Do Multi-Party Municipal Councils Improve Local Governance? Municipal Councillors’ Opinions in El Salvador
Creators: name: Córdova, Abby
name: España-Nájera, Annabella
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, online supplementary file 1, for Do Multi-Party Municipal Councils Improve Local Governance? Municipal Councillors’ Opinions in El Salvador by Abby Córdova and Annabella España-Nájera in Journal of Politics in Latin America
The Development of the Kachruvian paradigm: A Descriptive Study
Creators: name: Li, Yiyang
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: English as a second language

description: This dissertation presents the development of the Kachruvian paradigm of world Englishes and sheds light on keynotions in each developmental stage of Braj Kachru’s research. It intends to answer the question: how was the Kachruvian paradigm of world Englishes formed? Thiswas not the initial aim of the project. Instead, its significance has two phases, a pre-project and post-project phase. The pre-project goal was an attempt to clarify various misunderstandings or misrepresentations of world Englishes as a field of study as well as a sociolinguistic phenomenon. However, when approaching the completion of this dissertation, the actual significance (the post-project) gradually shifted. It evolved into a working answer to the research question, that is what events and influences reveal the process of the development of what has come to be known as the Kachruvian paradigm of world Englishes. The beginning of the process can be dated back to Braj Kachru’s graduate school years, when he hesitated to affirm the linguistic and sociolinguistic existence of Indian English; his death marked the end of his development of the paradigm, but the field of world Englishes, which had reached global interest long before then, has continued to cultivate scholars of English varieties around the world. The description of the development of the paradigm undertaken in this dissertation is a close review of Kachru’s work over five decades (the 1960s to the 2000s).
Additional file 3 of Identification of QTL for kernel weight and size and analysis of the pentatricopeptide repeat (PPR) gene family in cultivated peanut (Arachis hypogaea L.)
Creators: name: Fang, Yuanjin
name: Liu, Hua
name: Qin, Li
name: Qi, Feiyan
name: Sun, Ziqi
name: Wu, Jihua
name: Dong, Wenzhao
name: Huang, Bingyan
name: Zhang, Xinyou
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3: Fig S2. Correlation between HKW, KA, KL and KW in Yuanyang 2021.
Pterossauros
Creators: name: Braga, Camila de Souza
name: Fogarolli, Vitor Arré
Publisher: name: Zenodo
Year: 2024

description: O termo pterossauros compreende répteis alados que existiram há 220 milhões de anos atrás no mesozoico,extinguindo entre o período cretáceo (145 – 65 milhões de anos) e Paleógeno (65 – 23 milhões de anos). Eles foram osprimeiros vertebrados capazes de voo ativo e tinham diversas formas corporais, desde animais com abertura das suasasas menor que um palmo a mais de 11 metros (BUFFETAUT; MAZIN, 2003; KELLNER, 2015).
Marianna Charitonidou, "Intersectional Theory in Architectural and Urban History: Digital Curation and Archives of Architects", in Rosa Tamborrino, ed., Città che si adattano?/Adaptive Cities? Volume 4 (Turin: AISU International, 2024), 1329-1337.
Creators: name: Charitonidou, Marianna
Publisher: name: AISU International
Year: 2024

description: This paper explores the role of digital curators in architectural archives and their use of intersectional theory and practice to examine the representation of women and black men in the digital curation of architectural drawings in cultural institutions. It investigates how concepts and tools from intersectionality can inform digital curation strategies by considering gender and race aspects. The hypothesis is that visualization strategies can show the evolution of the role of women and black people in architectural discourse. These cultural institutions operate within a contradictory context: while they hold archives of architects that align with the dominant discourse, they also aim to develop interpretative models that address diversity issues.
Additional file 1 of Rapid and accurate genotyping of human SNP rs671 in aldehyde dehydrogenase 2 gene using one-step CRISPR/Cas12b assay without DNA amplification
Creators: name: Wu, Fang
name: Xue, Yong
name: Wang, Yan
name: Si, Xinxin
name: Zhang, Xinyue
name: Xu, Yuyang
name: Luo, Zhidan
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Table S1. Sequences of sgRNA candidates in this study.
Supplemental Material, sj-pdf-6-tva-10.1177_15248380211032213 - PTSD in the Year Following Sexual Assault: A Meta-Analysis of Prospective Studies
Creators: name: Dworkin, Emily R.
name: Jaffe, Anna E.
name: Bedard-Gilligan, Michele
name: Fitzpatrick, Skye
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, sj-pdf-6-tva-10.1177_15248380211032213 for PTSD in the Year Following Sexual Assault: A Meta-Analysis of Prospective Studies by Emily R. Dworkin, Anna E. Jaffe, Michele Bedard-Gilligan and Skye Fitzpatrick in Trauma, Violence, & Abuse
sj-docx-1-psp-10.1177_01461672211030816 – Supplemental material for A Polarized Discourse: Effects of Opinion Differentiation and Structural Differentiation on Communication
Creators: name: Koudenburg, Namkje
name: Kashima, Yoshihisa
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-psp-10.1177_01461672211030816 for A Polarized Discourse: Effects of Opinion Differentiation and Structural Differentiation on Communication by Namkje Koudenburg and Yoshihisa Kashima in Personality and Social Psychology Bulletin
Integration of UAVS with Real Time Operating Systems and Establishing a Secure Data Transmission
Creators: name: RAVI, NIRANJAN
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Autonomous vehicle systems
Circuits and systems
Digital processor architectures
Other information and computing sciences not elsewhere classified
Electrical engineering not elsewhere classified
Aerospace engineering not elsewhere classified
Avionics

description: In today’s world, the applications of Unmanned Aerial Vehicle (UAV) systems are leaping by extending their scope from military applications on to commercial and medical sectors as well. Owing to this commercialization, the need to append external hardware with UAV systems becomes inevitable. This external hardware could aid in enabling wireless data transfer between the UAV system and remote Wireless Sensor Networks (WSN) using low powered architecture like Thread, BLE (Bluetooth Low Energy). The data is being transmitted from the flight controller to the ground control station using a MAVlink (Micro Air Vehicle Link) protocol. But this radio transmission method is not secure, which may lead to data leakage problems. The ideal aim of this research is to address the issues of integrating different hardware with the flight controller of the UAV system using a light-weight protocol called UAVCAN (Unmanned Aerial Vehicle Controller Area Network). This would result in reduced wiring and would harness the problem of integrating multiple systems to UAV. At the same time, data security is addressed by deploying an encryption chip into the UAV system to encrypt the data transfer using ECC (Elliptic curve cryptography) and transmitting it to cloud platforms instead of radio transmission.
Uma contribuição ao estudo da extinção florística de Angiospermas no intervalo de tempo Kpg.
Creators: name: Saidenberg, Muriel
Publisher: name: Zenodo
Year: 2024

description: Adolphe Théodore Brongniart1 (1801-1876), considerado um dos fundadores da paleobotânica, elaboroualgumas das primeiras classificações de plantas como monocotiledôneas, dicotiledôneas, gimnospermas ouangiospermas. Seus trabalhos serviram como base para a construção da paleobotânica moderna e, entre suas diversascontribuições para o campo, encontra-se o artigo "Tableau des genres de végétaux fossiles", publicado no "Dictionnaireuniversel d'histoire naturelle"2 em 1849 (POWELL, 1885, p. 372), no qual Brongniart dividiu o tempo geológico emtrês reinos de acordo com a proeminência de diferentes grupos vegetais (BRONGNIART, 1850, p. 74).
Additional file 1 of A RCT to explore the effectiveness of supporting adherence to nebuliser medication in adults with cystic fibrosis: fidelity assessment of study interventions
Creators: name: Bradley, J. M.
name: Hutchings, M.
name: Arden, M. A.
name: O’Cathain, A.
name: Maguire, C.
name: Wildman, M. J.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1.
sj-docx-1-psp-10.1177_01461672211031080 – Supplemental material for You and I Both: Self-Compassion Reduces Self–Other Differences in Evaluation of Showing Vulnerability
Creators: name: Bruk, Anna
name: Scholl, Sabine G.
name: Bless, Herbert
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-psp-10.1177_01461672211031080 for You and I Both: Self-Compassion Reduces Self–Other Differences in Evaluation of Showing Vulnerability by Anna Bruk, Sabine G. Scholl and Herbert Bless in Personality and Social Psychology Bulletin
USING MACHINE LEARNING TECHNIQUES TO IMPROVE STATIC CODE ANALYSIS TOOLS USEFULNESS
Creators: name: Alikhashashneh, Enas Ahmad
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Software engineering not elsewhere classified
Knowledge representation and reasoning

description: This dissertation proposes an approach to reduce the cost of manual inspections for as large a number of false positive warnings that are being reported by Static Code Analysis (SCA) tools as much as possible using Machine Learning (ML) techniques. The proposed approach neither assume to use the particular SCA tools nor depends on the specific programming language used to write the target source code or the application. To reduce the number of false positive warnings we first evaluated a number of SCA tools in terms of software engineering metrics using a highlighted synthetic source code named the Juliet test suite. From this evaluation, we concluded that the SCA tools report plenty of false positive warnings that need a manual inspection. Then we generated a number of datasets from the source code that forced the SCA tool to generate either true positive, false positive, or false negative warnings. The datasets, then, were used to train four of ML classifiers in order to classify the collected warnings from the synthetic source code. From the experimental results of the ML classifiers, we observed that the classifier that built using the Random Forests (RF) technique outperformed the rest of the classifiers. Lastly, using this classifier and an instance-based transfer learning technique, we ranked a number of warnings that were aggregated from various open-source software projects. The experimental results show that the proposed approach to reduce the cost of the manual inspection of the false positive warnings outperformed the random ranking algorithm and was highly correlated with the ranked list that the optimal ranking algorithm generated.
Supplemental Material, sj-pdf-2-jpx-10.1177_23743735211033126 - Assessing the Educational and Supportive Care Needs of Canadian Metastatic Melanoma Patients and Survivors Attending an Outpatient Clinic
Creators: name: Subasri, Mathushan
name: Lemonde, Manon
name: Mundluru, Jahnavi
name: Chang, Jose
name: Koneru, Rama
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Medicine

description: Supplemental Material, sj-pdf-2-jpx-10.1177_23743735211033126 for Assessing the Educational and Supportive Care Needs of Canadian Metastatic Melanoma Patients and Survivors Attending an Outpatient Clinic by Mathushan Subasri, Manon Lemonde, Jahnavi Mundluru, Jose Chang and Rama Koneru in Journal of Patient Experience
Формування науково-дослідницької компетентності здобувачів вищої освіти в умовах інноваційного університетського середовища
Creators: name: Слодиницька Юлія Русланівна
Publisher: name: Zenodo
Year: 2025
Subjects: академічна мобільність, цифровізація, міждисциплінарність, професійна підготовка, міжнародне співробітництво, інноваційні стратегії, навчальні технології, студентська активність

description: У статті досліджується проблема формування науково-дослідницької компетентності здобувачів вищої освіти в контексті інноваційного університетського середовища. Проаналізовано сутність, структуру та особливості науково-дослідницької компетентності як інтегративної якості майбутнього фахівця. Обґрунтовано психолого-педагогічні умови ефективного формування дослідницьких навичок студентів. Представлено авторську модель формування науково-дослідницької компетентності, яка інтегрує традиційні та інноваційні підходи до організації дослідницької діяльності. Висвітлено результати експериментальної перевірки ефективності запропонованої системи. Розроблено методичні рекомендації щодо впровадження інноваційних технологій у процес формування науково-дослідницької компетентності.
PEER-TO-PEER PERSONAL HEALTH RECORD
Creators: name: Horne, William C
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Health surveillance

description: Patients and providers need to exchange medical records. Electronic Health Records and Health Information Exchanges leave a patient’s health record fragmented and controlled by the provider. This thesis proposes a Peer-to-Peer Personal Health Record network that can be extended with third-party services. This design enables patient control of health records and the tracing of exchanges. Additionally, as a demonstration of the functionality of a potential third-party, a Hypertension Predictor is developed using MEPS data and deployed as a service in the proposed framework.
EARTH RSMA Theory: Earth's Function as an AC Engine
Creators: name: Ivan Markić
Publisher: name: Zenodo
Year: 2024

description: The concept of Earth functioning similarly to an AC engine provides a unique lens through which we can examine and understand Earth's geophysical processes. This theory, termed EARTH RSMA (Rotor-Stator-Magnetic-Atmospheric) Theory, suggests that the Earth's core, its magnetic field, the surrounding space, and atmospheric phenomena interact in ways analogous to the components of an AC engine. This paper will explore this analogy in detail, provide empirical evidence, and discuss potential implications for our understanding of Earth's dynamics.
OPTIMAL SUBSAMPLING FOR MASSIVE PENALIZED SPINE SINGLE INDEX MODELS
Creators: name: Smithson, Haixia
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Applied statistics

description: The semiparametric single index model is well known as a compromise between parametric and nonparametric regression models, with its response mean dependent on a linear combination of covariates through an unknown univariate function. It has been widely studied due to its simplicity and flexibility, yet the challenge of its application exists especially for large datasets. This thesis focuses on the subsampling approach to fit a semiparametric single index models on large datasets, which can be computationally difficult due to the long calculating time and its high requirements on storage memory. By subsampling, the estimation on subsample, called the subsampling estimator, is used to approximate the estimation on the full sample, called the full sample estimator. To obtain an optimal sampling probability for subsampling, i.e., the optimal subsampling method, we first study the asymptotic properties of the subsampling estimator in a general semiparametric single index model with a general subsampling method, then we derive the formula of the optimal sampling probability by minimizing the asymptotic MSE of the subsampling estimator. We consider specific models in simulation studies and real data applications to investigate the numerical performance of the optimal subsampling method.
title: Staatliche Beihilfen unterstützen vor allem Kleinst- und Kleinunternehmen in Krisenzeiten: Interview
Creators: name: Duso, Tomaso
name: Wittenberg, Erich
Publisher: name: DIW - Deutsches Institut für Wirtschaftsforschung
Year: 2025

description: DIW Wochenbericht, 92 (2025), 19, S. 274
sj-pdf-1-mso-10.1177_20552173211024298 - Supplemental material for Treatment-emergent adverse events occurring early in the treatment course of cladribine tablets in two phase 3 trials in multiple sclerosis
Creators: name: Oh, Jiwon
name: Walker, Bryan
name: Giovannoni, Gavin
name: Jack, Dominic
name: Dangond, Fernando
name: Nolting, Axel
name: Aldridge, Julie
name: Lebson, Lori A
name: Leist, Thomas P
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Neuroscience

description: Supplemental material, sj-pdf-1-mso-10.1177_20552173211024298 for Treatment-emergent adverse events occurring early in the treatment course of cladribine tablets in two phase 3 trials in multiple sclerosis by Jiwon Oh, Bryan Walker, Gavin Giovannoni, Dominic Jack, Fernando Dangond, Axel Nolting, Julie Aldridge, Lori A Lebson and Thomas P Leist in Multiple Sclerosis Journal—Experimental, Translational and Clinical
title: Lehren aus der Corona-Pandemie: Staatliche Beihilfen unterstützten vor allem kleine Unternehmen bei der Krisenbewältigung
Creators: name: Duso, Tomaso
name: Canzian, Giulia
name: Crivellaro, Elena
name: Ferrara, Antonella Rita
name: Sasso, Alessandro
name: Verzillo, Stefano
Publisher: name: DIW - Deutsches Institut für Wirtschaftsforschung
Year: 2025
Subjects: subject: D04 Microeconomic Policy: Formulation; Implementation; Evaluation
subject: G21 Banks; Other Depository Institutions; Micro Finance Institutions; Mortgages
subject: P43 Other Economic Systems: Public Economics; Financial Economics
subject: State Aid
subject: Aid Effectiveness
subject: Temporary Framework
subject: Covid
subject: Firm Growth
subject: Investment

description: Die Europäische Union überwacht staatliche Beihilfen für Unternehmen streng, reagierte jedoch in Krisenzeiten mit der Einführung eines sogenannten befristeten Rahmens, um die Beihilferegeln vorübergehend zu lockern. Im Zuge der Corona-Pandemie wurde ein befristeter Rahmen geschaffen, der umfangreiche staatliche Beihilfen zur Stabilisierung der Wirtschaft ermöglichte. Die vorliegende Studie untersucht die Wirksamkeit dieser Maßnahmen in Spanien und Italien, zwei von der Pandemie besonders betroffenen Ländern. In beiden Ländern wurden Unternehmen in erheblichem Umfang staatliche Beihilfen gewährt. Um deren Wirkung zu analysieren, wurden Unternehmen, die Beihilfen erhielten, mit Unternehmen verglichen, die nicht unterstützt wurden. Die Ergebnisse zeigen, dass die Unterstützung insbesondere Mikro- und Kleinunternehmen half, Umsatzeinbrüche abzufedern, und dass sie die Investitionstätigkeit förderte. Eine staatliche, zeitlich begrenzte Unterstützung kann in Krisenzeiten für das Überleben und die Entwicklung von kleinen Unternehmen zwar wichtig sein. Vorsicht ist indes geboten, wenn derartige Instrumente im Rahmen des Clean Industrial Deal der EU-Kommission auf große Unternehmen ausgeweitet und dauerhaft eingesetzt werden sollten. Dies könnte zu starken Verzerrungen des Wettbewerbs führen.
description: DIW Wochenbericht, 92 (2025), 19, S. 265-273
title: A sociological analysis of top incomes and wealth:
title: a study of how individuals at the top of the income and wealth distributions perceive economic inequality.
titleType: Subtitle
Creators: name: Hecht, Katharina Maria
Publisher: name: London School of Economics and Political Science (LSE)
Year: 2017
Subjects: subject: HM Sociology

description: While economic research has demonstrated that the richest 1 percent in terms of income (and to a lesser extent in terms of wealth) in the UK have increased their relative advantage since the 1980s, there is little empirical research on how these individuals perceive changes in economic inequality (Chin, 2014). Following in the tradition of research on ‘elite’ perceptions of inequality (Reis and Moore, 2005), my research investigates how economic inequality, measured by top income and wealth shares, is perceived by the top 1 percent of income earners in the UK. To understand these phenomena, I interviewed and surveyed 30 participants. Additionally, I analysed data from the Great British Class Survey (GBCS) to triangulate the findings. Participants’ perceptions of top income shares closely relate to their views on the production of top incomes. For instance, GBCS data show that respondents with the highest incomes tend to select meritocratic items as important for career success. Meanwhile, a majority of interviewees, termed ‘economic evaluators’, narrate top incomes as resulting from rational, economic evaluation processes (Lamont et al., 2014), based on the idea that ‘the market’ is the best instrument for the distribution of resources. Intersectional privilege can be reconciled with ideas of a neutral market, because economic evaluative processes are gendered, ‘raced’ and classed (Skeggs, 2004a). Due to vast absolute differences between those at the top, participants view inequality from the perspective of ‘relative (dis)advantage’; while recognizing their advantage compared to the general population they experience relative disadvantage (based on Runciman’s (1966) ‘relative deprivation’) compared to others higher up the distribution. As a result, participants overestimate top income and wealth shares. Due to beliefs in markets, participants’ heightened awareness of inequality does not translate into general concern for inequality, particularly among economic evaluators. My study highlights the importance of the evaluative processes narrated as constituting top incomes for top income earners’ perceptions of economic inequality.
sj-pdf-1-jhs-10.1177_17531934211027499 - Supplemental material for Hyperselective neurectomy for the treatment of upper limb spasticity in adults and children: a prospective study
Creators: name: Leclercq, Caroline
name: Perruisseau-Carrier, Anne
name: Gras, Mathilde
name: Panciera, Paolo
name: Fulchignoni, Camillo
name: Fulchignoni, Marcello
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-jhs-10.1177_17531934211027499 for Hyperselective neurectomy for the treatment of upper limb spasticity in adults and children: a prospective study by Caroline Leclercq, Anne Perruisseau-Carrier, Mathilde Gras, Paolo Panciera, Camillo Fulchignoni and Marcello Fulchignoni in Journal of Hand Surgery (European Volume)
Nursing staff fluctuation and pathogenic burden in the NICU - effective outbreak management and the underestimated relevance of non-resistant strains
Creators: name: Hensel, Kai O.
name: Bruck, Rhea Van Den
name: Klare, Ingo
name: Heldmann, Michael
name: Ghebremedhin, Beniam
name: Jenke, Andreas C.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2017
Subjects: subject: 610 Medizin

description: In the course of a hospital management takeover, a microbial outbreak took place in a tertiary neonatal intensive care unit (NICU). Here, we characterize the outbreak and its management. About 4 months prior to takeover, there was a sharp increase in positive isolates for MSSA and multidrug-resistant organisms (MDROs). Simultaneously, the nursing staff sick leave rate increased dramatically which directly correlated with the number of infection/colonization per week (r2 = 0.95, p = 0.02). During the following months we observed several peaks in positive isolates of methicillin-sensitive staphylococcus aureus (MSSA), MDROs and subsequently a vancomycin-resistant enterococcus (VRE) outbreak. Interventional outbreak management measures were only successful after substantial recruitment of additional nursing staff. None of the VRE, but 44% (n = 4) of MDRO and 32% (n = 23) of MSSA colonized infants developed symptomatic infections (p = 0.02). Among the latter, 35% suffered from serious consequences such as osteomyelitis. The most important risk factors for colonization-to-infection progression were low gestational age and birth weight. Nursing staff fluctuation poses a substantial risk for both bacterial colonization and infection in neonates. Comprehensive outbreak management measures are only successful if adequate nursing staff is available. Non resistant strains account for most neonatal infections – possibly due to their limited perception as being harmful.
Additional file 1 of APOE ε4 carriage associates with improved myocardial performance from adolescence to older age
Creators: name: Topriceanu, Constantin-Cristian
name: Shah, Mit
name: Webber, Matthew
name: Chan, Fiona
name: Shiwani, Hunain
name: Richards, Marcus
name: Schott, Jonathan
name: Chaturvedi, Nishi
name: Moon, James C.
name: Hughes, Alun D.
name: Hingorani, Aroon D.
name: O’Regan, Declan P.
name: Captur, Gabriella
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Science Policy
subject: Biological Sciences not elsewhere classified

description: Additional file 1: Supplementary Tables S1-S5.
KLARpsy-Text: Welchen Nutzen bringt Coaching am Arbeitsplatz?
Creators: name: ZPID
Publisher: name: KLARpsy
Year: 2024
Subjects: subject: 150

description: KLARpsy-Texte sind kurze, lai:innengerechte, allgemeinverständliche und richtlinienbasierte Zusammenfassungen psychologischer Übersichtsarbeiten. Dieser KLARpsy-Text hat den Titel “Welchen Nutzen bringt Coaching am Arbeitsplatz?”. Er wurde von Mitarbeitenden des Leibniz-Instituts für Psychologie verfasst. Eine anonyme testlesende Person war beteiligt. Der KLARpsy-Text befasst sich mit folgenden Inhalten: Immer häufiger lassen Unternehmen Coachings am Arbeitsplatz durchführen. Dennoch ist wenig über den tatsächlichen Nutzen oder die konkreten Auswirkungen von Coaching auf die Fähigkeiten, die Motivation und die Leistungen von Beschäftigten bekannt. Um Coaching am Arbeitsplatz möglichst zielführend einsetzen zu können, ist es wichtig zu wissen, wie es am besten wirkt. Mit ihrer Übersichtsarbeit wollten die Forschenden herausfinden: 1. Hilft Coaching am Arbeitsplatz Beschäftigten, ihre Fähigkeiten und Leistungen zu verbessern und ihre Motivation zu steigern? 2. Welche Merkmale sollte das Coaching haben, um besonders gut zu wirken? Coaching am Arbeitsplatz verbessert die Fähigkeiten, die Motivation und die Leistungen von Beschäftigten. Das Coaching wirkt besser, wenn es ohne Feedback von verschiedenen Quellen (wie Vorgesetzten oder Kund:innen) durchgeführt wird. Es wirkt auch besser, wenn die coachende Person aus dem Unternehmen kommt.
Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers
Creators: name: Chereau, Fanny
name: Madec, Yoann
name: Sabin, Caroline
name: Obel, Niels
name: Ruiz-Mateos, Ezequiel
name: Chrysos, Georgios
name: Fidler, Sarah
name: Lehmann, Clara
name: Zangerle, Robert
name: Wittkop, Linda
name: Reiss, Peter
name: Hamouda, Osamah
name: Perez, Vicente Estrada
name: Leal, Manuel
name: Mocroft, Amanda
name: Olalla, Patricia Garcia De
name: Ammassari, Adriana
name: Monforte, Antonella D'Arminio
name: Mussini, Cristina
name: Segura, Ferran
name: Castagna, Antonella
name: Cavassini, Matthias
name: Grabar, Sophie
name: Meyer, Laurence
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2017
Subjects: subject: 610 Medizin

description: Objective: HIV controllers (HICs) spontaneously maintain HIV viral replication at low level without antiretroviral therapy (ART), a small number of whom will eventually lose this ability to control HIV viremia. The objective was to identify factors associated with loss of virological control. Methods: HICs were identified in COHERE on the basis of ≥5 consecutive viral loads (VL) ≤500 copies/mL over ≥1 year whilst ART-naive, with the last VL ≤500 copies/mL measured ≥5 years after HIV diagnosis. Loss of virological control was defined as 2 consecutive VL >2000 copies/mL. Duration of HIV control was described using cumulative incidence method, considering loss of virological control, ART initiation and death during virological control as competing outcomes. Factors associated with loss of virological control were identified using Cox models. CD4 and CD8 dynamics were described using mixed-effect linear models. Results: We identified 1067 HICs; 86 lost virological control, 293 initiated ART, and 13 died during virological control. Six years after confirmation of HIC status, the probability of losing virological control, initiating ART and dying were 13%, 37%, and 2%. Current lower CD4/CD8 ratio and a history of transient viral rebounds were associated with an increased risk of losing virological control. CD4 declined and CD8 increased before loss of virological control, and before viral rebounds. Discussion: Expansion of CD8 and decline of CD4 during HIV control may result from repeated low-level viremia. Our findings suggest that in addition to superinfection, other mechanisms, such as low grade viral replication, can lead to loss of virological control in HICs.
Ancient Recombination Events between Human Herpes Simplex Viruses
Creators: name: Burrel, Sonia
name: Boutolleau, David
name: Ryu, Diane
name: Agut, Henri
name: Merkel, Kevin
name: Leendertz, Fabian H.
name: Calvignac-Spencer, Sébastien
Publisher: name: Robert Koch-Institut
Year: 2017
Subjects: subject: recombination
subject: human herpes simplex virus
subject: phylogenomics
subject: 610 Medizin

description: Herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) are seen as close relatives but also unambiguously considered as evolutionary independent units. Here, we sequenced the genomes of 18 HSV-2 isolates characterized by divergent UL30 gene sequences to further elucidate the evolutionary history of this virus. Surprisingly, genome-wide recombination analyses showed that all HSV-2 genomes sequenced to date contain HSV-1 fragments. Using phylogenomic analyses, we could also show that two main HSV-2 lineages exist. One lineage is mostly restricted to subSaharan Africa whereas the other has reached a global distribution. Interestingly, only the worldwide lineage is characterized by ancient recombination events with HSV-1. Our findings highlight the complexity of HSV-2 evolution, a virus of putative zoonotic origin which later recombined with its human-adapted relative. They also suggest that coinfections with HSV-1 and 2 may have genomic and potentially functional consequences and should therefore be monitored more closely.
title: How media coverage elicits strategic change: The moderating role of the business model design
Creators: name: Klein, Sascha Pascal
name: Spieth, Patrick
name: Ricart, Joan Enric
Publisher: name: KOBRA Universität Kassel
Year: 2024
Subjects: subject: business model design
subject: innovation
subject: media coverage
subject: panel data
subject: strategic change
classificationCode: 330
subject: 330
classificationCode: Geschäftsmodell
subject: Geschäftsmodell
classificationCode: Berichterstattung
subject: Berichterstattung
classificationCode: Presse
subject: Presse

description:
Research Summary: Prior research indicates that negative media coverage of business activities encourages a firm to engage in strategic change, but the conditions
for this strategic focus have drawn less scholarly attention. Considering a firm's business model design (BMD) with distinct sources for value creation, we argue that the effect of negative media coverage on strategic change is contingent on the BMD. An analysis of
longitudinal data from 96 established firms shows that novelty-centered BMDs reduce strategic change in response to negative media coverage. We contribute to
research regarding strategic change in response to outside evaluations by explaining an important contingent factor related to strategy. We also expand on previous
research indicating that managerial behaviors and attributes moderate the main effect of negative media coverage and provide a more nuanced understanding of
this effect from a business model perspective.

Managerial Summary: Our study explores how negative media coverage affects strategic changes in large firms, focusing on the role of the BMD. We found that
firms with a novelty-centered BMD prioritizing innovation are less likely to alter their strategies in response to negative media coverage, suggesting that these firms are
confident in their innovative approaches despite external criticism. Conversely, efficiency-centered BMDs, which focus on operational efficiency, did not show a meaningful moderating effect. For managers, this implies that firms with innovation-oriented business models may need less frequent strategic adjustments in the face of negative media. However, they should still communicate strategically to address potential long-term reputational risks.
sj-docx-1-hpo-10.1177_20551029211029158 – for Couples talk about breastfeeding: Interviews with parents about decision-making, challenges, and the role of fathers and professional support
Creators: name: Henshaw, Erin J
name: Mayer, Maria
name: Balraj, Sarina
name: Parmar, Elsie
name: Durkin, Kristine
name: Snell, Rita
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: sj-docx-1-hpo-10.1177_20551029211029158 for Couples talk about breastfeeding: Interviews with parents about decision-making, challenges, and the role of fathers and professional support by Erin J Henshaw, Maria Mayer, Sarina Balraj, Elsie Parmar, Kristine Durkin and Rita Snell in Health Psychology Open
KLARpsy-Text: Wie hängt die Fähigkeit, mit Gefühlen umzugehen, mit der Qualität von Beziehungen zusammen?
Creators: name: ZPID
Publisher: name: KLARpsy
Year: 2024
Subjects: subject: 150

description: KLARpsy-Texte sind kurze, lai:innengerechte, allgemeinverständliche und richtlinienbasierte Zusammenfassungen psychologischer Übersichtsarbeiten. Dieser KLARpsy-Text hat den Titel “Wie hängt die Fähigkeit, mit Gefühlen umzugehen, mit der Qualität von Beziehungen zusammen?”. Er wurde von Mitarbeitenden des Leibniz-Instituts für Psychologie verfasst. Eine anonyme testlesende Person war beteiligt. Der KLARpsy-Text befasst sich mit folgenden Inhalten: Enge Beziehungen beeinflussen unser Wohlbefinden und unsere Gesundheit stark. Dabei spielt die Fähigkeit, mit Gefühlen umzugehen, die emotionale Kompetenz , eine entscheidende Rolle. Sie verbessert laut Studien die Qualität von Liebesbeziehungen und Freundschaften. Wie groß der Zusammenhang je nach Art der Beziehungen ist und was ihn beeinflusst, ist dagegen noch unklar. Mit ihrer Übersichtsarbeit wollten die Forschenden herausfinden: 1. Wie hängt die Fähigkeit, mit Gefühlen umzugehen, mit der Qualität von Liebesbeziehungen und anderen Beziehungen zusammen? 2. Was beeinflusst den Zusammenhang? Die Fähigkeit, mit Gefühlen umzugehen und die Qualität von Beziehungen hängen zusammen. Menschen, die besser mit ihren Gefühlen umgehen können, sind in ihren Beziehungen eher glücklicher. Bei Liebesbeziehungen ist der Zusammenhang größer als bei anderen Beziehungen, wie zum Beispiel Freundschaften. Besonders groß ist der Zusammenhang bei Beziehungen, die seit etwa 8 bis 11 Jahren bestehen.
Additional file 1 of Increased incidence of adult-onset Still’s disease in association with COVID-19 vaccination and SARS-CoV-2 infection
Creators: name: Gottschalk, Maxime N.
name: Heiland, Max
name: Nahles, Susanne
name: Preissner, Robert
name: Petri, William A.
name: Wendy, Stephanie
name: Preissner, Saskia
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file1. Figure S1: Demographics for Primary cohort (AOSD). Figure S2: Demographics for Cov cohort (AOSD + SARS-CoV-2 infection). Figure S3: Demographics for Vac cohort (AOSD + COVID-19 vaccination). Figure S4: Demographics for Vac+Cov cohort (AOSD + COVID-19 vaccination + SARS-CoV-2 infection). Figure S5: Modified CONSORT flow chart for the different cohorts.
Urban planning methods as tangible and intangible expression in Constantinos Doxiadis and Adriano Olivetti's approaches: Revisiting their work via the lenses of urban-scale digital twins
Creators: name: Charitonidou, Marianna
name: Gospodini, Aspa
Publisher: name: University of Thessaly
Year: 2024
Subjects: subject: City and town life--Study and teaching
subject: Cities and towns--Growth--Management
subject: Cities and towns--History--Research
subject: Architecture--Details--History

description: At the heart of the paper is the development of methodological tools that offer the possibility of developing new forms of participatory planning by linking the use of artificial intelligence and big data in urban planning with the holistic approaches of urban planning of Constantinos A. Doxiadis and Adriano Olivetti. The paper pays special attention to the role of tangible and intangible expression in Doxiadis and Olivetti's thought, and to how their approaches understood the relationship with place identity and sustainable planning and development. Particular emphasis is placed on the concepts of 'entopia', 'ekistics', and 'Ecumenopolis' in Doxiadis's thought, on the concept of 'concrete utopia' in Olivetti's approach, and on the role of visualization via the use of computers in the case of Doxiadis Associates Computer Centrer (DACC). Urban scale digital twins, which have as a core characteristic the possibility to be updated in real-time thanks to the use of technologies such as big data and artificial intelligence, aim to compare different strategies during the processes of decision-making concerning urban and spatial planning. At the core of the paper is the comparison of the ongoing and growing use of urban scale digital twins applications in decision making in urban planning with the methods of visualization used in the case of Athens Center of Ekistics.
KLARpsy-Text: Wie hängen unsere Absichten und Gewohnheiten mit unserem Verhalten zusammen?
Creators: name: ZPID
Publisher: name: KLARpsy
Year: 2024
Subjects: subject: 150

description: KLARpsy-Texte sind kurze, lai:innengerechte, allgemeinverständliche und richtlinienbasierte Zusammenfassungen psychologischer Übersichtsarbeiten. Dieser KLARpsy-Text hat den Titel 'Wie hängen unsere Absichten und Gewohnheiten mit unserem Verhalten zusammen?'. Er wurde von Mitarbeitenden des Leibniz-Instituts für Psychologie verfasst. Als testlesende Person war Micha beteiligt. Der KLARpsy-Text befasst sich mit folgenden Inhalten: In der Psychologie geht man oft davon aus, dass Menschen ihr Verhalten absichtlich und bewusst steuern. Neuere Forschung zeigt jedoch, dass Verhalten häufig automatisch abläuft. Eine zentrale Rolle spielt dabei die Gewohnheit: Sie entwickelt sich schrittweise, wenn wir ein bestimmtes Verhalten oft wiederholen. Eine Gewohnheit führt dazu, dass wir in vielen Situationen, ohne groß nachzudenken, handeln. Bewusste Entscheidungen auf Grundlage unserer Absichten sind dann weniger wichtig. Mit ihrer Übersichtsarbeit wollten die Forschenden herausfinden: 1. Wie stark beeinflussen Gewohnheiten und Absichten jeweils unser Verhalten? 2. Welche Rolle spielt dabei unser früheres Verhalten? Unsere Absichten und Gewohnheiten beeinflussen unabhängig voneinander unser aktuelles Verhalten. Wer die Absicht oder die Gewohnheit hat etwas zu tun, tut dies auch eher erneut.
No significant HTLV seroprevalence in German people who inject drugs
Creators: name: Hohn, Oliver
name: Norley, Stephen
name: Kücherer, Claudia
name: Bazarbachi, Ali
name: Hajj, Hiba El
name: Marcus, Ulrich
name: Zimmermann, Ruth
name: Bannert, Norbert
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger; Robert Koch-Institut, Infektionsepidemiologie
Year: 2017
Subjects: subject: 610 Medizin

description: Background: Although human T-lymphotropic virus (HTLV) is transmitted via the same routes as human immunodeficiency virus (HIV), its worldwide seroprevalence differs drastically because HTLV is transmitted mainly via infected cells rather than free virus. The sharing of needles and other equipment places people who inject drugs (PWID) at particularly high-risk for such blood-borne diseases. Methods: To validate the methodology used to process and analyze the dried blood spots (DBS) utilized in the study, dried serum spots (DSS) with dilutions of sera from known HTLV infected individuals were analyzed by ELISA and Western blot. DBS collected between 2011 and 2015 from 2,077 PWID in eight German cities recruited by respondent-driven sampling were tested for HTLV-specific antibodies. Results: The validation demonstrated that the use of DSS allowed identification of samples with even low titers of HTLV-specific antibodies, although a confirmatory Western blot with an additional venous blood sample would often be required. Despite numerous HIV and HCV positive individuals being identified within the study population, none tested positive for HTLV. Conclusion While the HIV and HCV prevalences in German PWID are comparable to those in other European countries, the very low prevalence of HTLV reflects the situation in the general population.
Berlin Squirrelpox Virus, a New Poxvirus in Red Squirrels, Berlin, Germany
Creators: name: Wibbelt, Gudrun
name: Tausch, Simon H.
name: Dabrowski, Piotr Wojtek
name: Kershaw, Olivia
name: Nitsche, Andreas
name: Schrick, Livia
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2017
Subjects: subject: 610 Medizin

description: Near Berlin, Germany, several juvenile red squirrels (Sciurus vulgaris) were found with moist, crusty skin lesions. Histology, electron microscopy, and cell culture isolation revealed an orthopoxvirus-like infection. Subsequent PCR and genome analysis identified a new poxvirus (Berlin squirrelpox virus) that could not be assigned to any known poxvirus genera.
North American Extra-Activism and Indigenous Communications Practices
Creators: name: Kidd, Dorothy
Publisher: name: Humanities Commons
Year: 2020
Subjects: subject: Communication
subject: Environmentalism
subject: Social movements

description: There has been a wealth of research in Latin America on the most recent global intensification of extractivism, or the capitalist exploitation of natural resources. Some of this research has examined the resistance among front-line Indigenous and rural communities, and allied environmental groups, who are challenging the development of mega-scale mining, oil, gas, mono-agricultural, and related infrastructural projects. Researchers have noted many similar tactical repertoires that can take multiple forms (through direct action, media representation, and in legal, political, and educational forums) and extend across geographic scales (local, national, regional, and transnational). Communications is key to much of their work; however there has been far less research examining the communications practices in any detail. This article focuses on the communications practices in use in three Indigenous-led campaigns against extractivist projects in North America, the decade-old Unist’ot’en Camp in northwestern Canada, Idle No More, and the #NoDAPL of the Standing Rock Sioux. My findings indicate that a resurgent Indigenous movement, in concert with environmental and other settler allies, has adopted an array of communications practices that combine protective action on behalf of their lands and waters with the creation of new communities in place-based assemblies and social media and digital networks.
KLARpsy-Text: Wie gut hilft Bewegung bei Depression?
Creators: name: ZPID
Publisher: name: KLARpsy
Year: 2024
Subjects: subject: 150

description: KLARpsy-Texte sind kurze, lai:innengerechte, allgemeinverständliche und richtlinienbasierte Zusammenfassungen psychologischer Übersichtsarbeiten. Dieser KLARpsy-Text hat den Titel 'Wie gut hilft Bewegung bei Depression?'. Er wurde von Mitarbeitenden des Leibniz-Instituts für Psychologie verfasst. Als testlesende Person war Ruben Brück beteiligt. Der KLARpsy-Text befasst sich mit folgenden Inhalten: Eine Depression ist für Betroffene und Angehörige sehr belastend. Zum Glück helfen Psychotherapie und Medikamente bei vielen Menschen mit Depression. Auch körperliche Aktivität könnte bei Depression helfen. Studien haben gezeigt, dass Bewegung positive Auswirkungen auf die psychische und körperliche Gesundheit hat. Es ist jedoch noch unklar, welche Art der Bewegung bei Depression am besten hilft. Mit ihrer Übersichtsarbeit wollten die Forschenden herausfinden: 1. Wie gut helfen verschiedene Formen von körperlicher Aktivität bei Depression? 2. Welche körperlichen Aktivitäten werden von Menschen mit Depression besonders gut angenommen? Yoga, Krafttraining, Walken oder Joggen helfen gut bei Depression. Yoga und Krafttraining werden von Menschen mit Depression außerdem besonders gut angenommen.