cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Die Untersuchung des Megalithgrabes Vale de Rodrigo 2, concelho Evora, Portugal : Vorbericht über die Ausgrabungen 1991-1995
title: Die Untersuchung des Megalithgrabes Vale de Rodrigo 2, concelho Evora, Portugal : Vorbericht über die Ausgrabungen 1991-1995
titleType: Subtitle
Creators: name: Larsson, Lars
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Vale de Rodrigo (Evora, Port.)
subject: Vale de Rodrigo (Evora, Port.)

description: Madrider Mitteilungen, Vol. 38 (1997)
description: Deutsche Zusammenfassung folgt.
Additional file 2: Tables S1 and S2. of Variants of cancer susceptibility genes in Korean BRCA1/2 mutation-negative patients with high risk for hereditary breast cancer
Creators: name: Park, Ji
name: Lee, Seung-Tae
name: Nam, Eun
name: Han, Jung
name: Jung-Yun Lee
name: Jieun Kim
name: Kim, Tae
name: Park, Hyung
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: This file includes two tables regarding baseline characteristics of study participants, possibly pathogenic variants and the classification according to ACMG guidelines mentied in the main manuscript. (DOCX 24 kb)
title: Geophysikalische Prospektion in Vale de Rodrigo, concelho de Evora, Portugal
title: Geophysikalische Prospektion in Vale de Rodrigo, concelho de Evora, Portugal
titleType: Subtitle
Creators: name: Becker, Helmut
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Vale de Rodrigo (Evora, Port.)
subject: Vale de Rodrigo (Evora, Port.)

description: Madrider Mitteilungen, Vol. 38 (1997)
description: Deutsche Zusammenfassung folgt.
Additional file 2 of Establishment and validation of a prognostic model based on HRR-related lncRNAs in colon adenocarcinoma
Creators: name: Tang, Xingkui
name: Lin, Yukun
name: He, Jialin
name: Luo, Xijun
name: Liang, Junjie
name: Zhu, Xianjun
name: Li, Tao
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Additional file 2: Supplementary Figure 2. Comparison of the expression of the nineteen HRR-related lncRNAs between the COAD and normal tissues.
Optical intra-day variability in 3C 66A: 10 years of observations
Creators: name: Kaur, Navpreet
name: Sameer
name: Baliyan, Kiran S.
name: Ganesh, S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present results based on the observations of the blazar 3C 66A from 2005 November 06 to 2016 February 14 in the BVR and I broadbands using 1.2m telescope of the Mt. Abu InfraRed Observatory (MIRO). The source was observed on 160 nights out of which on 89 nights it was monitored for more than 1 hr to check for the presence of any intra-day variability (IDV). The blazar 3C 66A exhibited significant variations in the optical flux on short and long term time scales. However, unlike highly variable S5 0716+71, it showed IDV duty cycle of about 8% only. Our statistical studies suggest the IDV time scales ranging from $\sim$ 37 min to about 3.12 hours and, in one case, a possibility of the quasi-periodic variations with characteristic timescale of $\sim$ 1.4 hrs. The IDV amplitudes in R$-$band were found to vary from 0.03 mag to as much as 0.6 mag, with larger amplitude of variation when the source was relatively fainter. The typical rate of the flux variation was estimated to be $\sim$0.07 mag hr$^{-1}$ in both, the rising and the falling phases. However, the rates of the brightness variation as high as 1.38 mag/hr were also detected. The shortest timescale of the variation, 37 min, sets an upper limit of $6.92 \times 10^{14}$ cm on the size of the emission region and about $3.7 \times 10^8\ \mathrm{M}_{\odot}$ as an estimate of the mass of the black hole, assuming the origin of the rapid optical variability is in close vicinity of the central SMBH. The long-term study suggests a mild bluer-when-brighter behavior, typical for BL Lacs.
description: Accepted for publication in MNRAS
title: Untersuchungen im Megalithgebiet von Vale de Rodrigo, concelho Évora, Portugal
title: Untersuchungen im Megalithgebiet von Vale de Rodrigo, concelho Évora, Portugal
titleType: Subtitle
Creators: name: Kalb, Philine
name: Höck, Martin
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Vale de Rodrigo (Evora, Port.)
subject: Vale de Rodrigo (Evora, Port.)

description: Madrider Mitteilungen, Vol. 38 (1997)
description: Deutsche Zusammenfassung folgt.
Diffractive molecular orbital tomography
Creators: name: Zhai, Chunyang
name: Zhu, Xiaosong
name: Lan, Pengfei
name: Wang, Feng
name: He, Lixin
name: Shi, Wenjing
name: Li, Yang
name: Li, Min
name: Zhang, Qingbin
name: Lu, Peixiang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: High harmonic generation in the interaction of femtosecond lasers with atoms and molecules opens the path to molecular orbital tomography and to probe the electronic dynamics with attosecond-Ångström resolutions. Molecular orbital tomography requires both the amplitude and phase of the high harmonics. Yet the measurement of phases requires sophisticated techniques and represents formidable challenges at present. Here we report a novel scheme, called diffractive molecular orbital tomography, to retrieve the molecular orbital solely from the amplitude of high harmonics without measuring any phase information. We have applied this method to image the molecular orbitals of N$_2$, CO$_2$ and C$_2$H$_2$. The retrieved orbital is further improved by taking account the correction of Coulomb potential. The diffractive molecular orbital tomography scheme, removing the roadblock of phase measurement, significantly simplifies the molecular orbital tomography procedure and paves an efficient and robust way to the imaging of more complex molecules.
description: 10 pages, 11 figures
title: Die Dekorelemente des spätumaiyadischen Fundkomplexes aus dem Cortijo del Alcaide (prov. Córdoba)
title: Die Dekorelemente des spätumaiyadischen Fundkomplexes aus dem Cortijo del Alcaide (prov. Córdoba)
titleType: Subtitle
Creators: name: Ewert, Christian
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Cortijo del Alcaide (Córdoba)
subject: Cortijo del Alcaide (Córdoba)

description: Madrider Mitteilungen, Vol. 39 (1998)
description: Deutsche Zusammenfassung folgt.
Additional file 2 of Gene expression in tonsils in swine following infection with porcine reproductive and respiratory syndrome virus
Creators: name: Dong, Qian
name: Lunney, Joan K.
name: Lim, Kyu-Sang
name: Nguyen, Yet
name: Hess, Andrew S.
name: Beiki, Hamid
name: Rowland, Raymond R. R.
name: Walker, Kristen
name: Reecy, James M.
name: Tuggle, Christopher K.
name: Dekkers, Jack C. M.
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 2: Table S1. Cell types included in the significant group. Table S2. Top three cell types explained by each principal component of cell type enrichments in the significant and the nuisance groups of cell types. Table S3. Numbers of differentially expressed genes in tonsil based on the RNA-seq data (q<0.1) with or without accounting for cell enrichments.
Additional file 1: Figure S1. of Z-ligustilide and anti-inflammatory prostaglandins have common biological properties in macrophages and leukocytes
Creators: name: Schwager, Joseph
name: Gagno, Lidia
name: Richard, Nathalie
name: Simon, Werner
name: Weber, Peter
name: Bendik, Igor
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Viability of RAW 264.7 cells after incubation with graded amounts of ligustilide, EGCG, resveratrol, 15d–PGJ2 and rosiglitazone for 24 h. Figure S2. Regulation of inflammatory gene expression in RAW264.7 cells by ligustilide (25 μM) rosiglitazone (25 μM) and 15d–PGJ2 (2.5 μM). Table S1. Synopsis of effects on protein secretion by (murine) macrophages or peripheral blood leukocytes (human). Table S1. Sequences of primers and probes used in quantitative real-time PCR. Table S2. Comparison of effects of PGJ2 and ligustilide on cytokines and chemokine expression. (DOCX 465 kb)
title: Spuren islamischer Besiedlung auf dem Castillo de Mulva (Villanueva del Río y Minas, prov. Sevilla)?
title: Spuren islamischer Besiedlung auf dem Castillo de Mulva (Villanueva del Río y Minas, prov. Sevilla)?
titleType: Subtitle
Creators: name: Teichner, Felix
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Munigua (Villanueva del Río y Minas, Sevilla)
subject: Munigua (Villanueva del Río y Minas, Sevilla)

description: Madrider Mitteilungen, Vol. 39 (1998)
description: Folgt.
On the fly control of high harmonic generation using a structured pump beam
Creators: name: Lobachinsky, Lilya
name: Hareli, Liran
name: Eliezer, Yaniv
name: Michaeli, Linor
name: Bahabad, Alon
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: High harmonic generation (HHG) is an extreme nonlinear frequency up-conversion process during which extremely short duration optical pulses at very short wavelengths are emitted. A major concern of HHG is the small conversion efficiency at the single emitter level. Thus ensuring that the emission at different locations are emitted in phase is crucial. At high pump intensities it is impossible to phase match the radiation without reverting to ordered modulations of either the medium or the pump field itself, a technique known as Quasi-Phase-Matching (QPM). To date, demonstrated QPM techniques of HHG were usually complicated and/or lacked tunability. Here we demonstrate experimentally a relatively simple, highly and easily tunable QPM technique by using a structured pump beam made of the interference of different spatial optical modes. With this technique we demonstrate on-the-fly, tunable quasi-phase-matching of harmonic orders 25 to 39 with up to 30 fold enhancement of the emission.
description: 13 pages, 4 figures
title: Un itinerario de peregrinaje para el culto martirial y veneración del agua bautismal en el complejo episcopal de Barcino
title: Un itinerario de peregrinaje para el culto martirial y veneración del agua bautismal en el complejo episcopal de Barcino
titleType: Subtitle
Creators: name: Godoy Fernández, Cristina
name: Gurt Esparraguera, Josep María
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Barcelona
subject: Barcelona

description: Madrider Mitteilungen, Vol. 39 (1998)
description: Folgt.
title: El complejo episcopal de Barcino : cuestiones sobre función e identificación de los edificios
title: El complejo episcopal de Barcino : cuestiones sobre función e identificación de los edificios
titleType: Subtitle
Creators: name: Godoy Fernández, Cristina
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Barcelona
subject: Barcelona

description: Madrider Mitteilungen, Vol. 39 (1998)
description: Folgt.
Additional file 1: Figure S1. of Benefits of VCE-003.2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson’s disease: possible involvement of different binding sites at the PPARγ receptor
Creators: name: García, Concepción
name: Gómez-Cañas, María
name: Burgaz, Sonia
name: Palomares, Belén
name: Gómez-Gálvez, Yolanda
name: Palomo-Garo, Cristina
name: Campo, Sara
name: Ferrer-Hernández, Joel
name: Pavicic, Carolina
name: Navarrete, Carmen
name: M. Luz Bellido
name: García-Arencibia, Moisés
name: M. Ruth Pazos
name: Muñoz, Eduardo
name: Fernández-Ruiz, Javier
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Double immunofluorescence analysis of Cd68 (in green) and TH (in red) in the substantia nigra pars compacta of adult male mice at 3 weeks of being subjected to an intrastriatal injection of LPS. Top panels show both immunostainings in the contralateral (lesioned) and ipsilateral (non-lesioned) sides (scale bar = 50 μm), whereas bottom panels show the immunostaining for both markers and the merged image in the contralateral (lesioned) side (scale bar = 50 μm), proving the presence of Cd68 immunostaining associated with TH-positive cells, but a complete lack of overlapping, then demonstrating that they correspond to different cells (TH-positive neurons versus Cd68-positive microglial cells) (PDF 757 kb)
An Optimally Weighted Estimator of the Linear Power Spectrum Disentangling the Growth of Density Perturbations Across Galaxy Surveys
Creators: name: Sorini, Daniele
Publisher: name: arXiv
Year: 2016
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Measuring the clustering of galaxies from surveys allows us to estimate the power spectrum of matter density fluctuations, thus constraining cosmological models. This requires careful modelling of observational effects to avoid misinterpretation of data. In particular, signals coming from different distances encode information from different epochs. This is known as "light-cone effect" and is going to have a higher impact as upcoming galaxy surveys probe larger redshift ranges. Generalising the method by Feldman et al. (1994), I define a minimum-variance estimator of the linear power spectrum at a fixed time, properly taking into account the light-cone effect. An analytic expression for the estimator is provided, and that is consistent with the findings of previous works in the literature. I test the method within the context of the halo model, assuming Planck 2014 cosmological parameters. I show that the estimator presented recovers the fiducial linear power spectrum at present time within 5% accuracy up to $k \sim 0.80\;h\,\mathrm{Mpc}^{-1}$ and within 10% up to $k \sim 0.94\;h\,\mathrm{Mpc}^{-1}$, well into the non-linear regime of the growth of density perturbations. As such, the method could be useful in the analysis of the data from future large-scale surveys, like Euclid.
description: 24 pages, 6 figures, submitted to JCAP
Additional file 3 of Establishment and validation of a prognostic model based on HRR-related lncRNAs in colon adenocarcinoma
Creators: name: Tang, Xingkui
name: Lin, Yukun
name: He, Jialin
name: Luo, Xijun
name: Liang, Junjie
name: Zhu, Xianjun
name: Li, Tao
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Additional file 3: Supplementary Figure 3. Comparison of ROC curve between the nineteen HRR-related lncRNAs prognostic model and other three published models in the TCGA-COAD cohort.
title: La villa romana de "El Saucedo" (Talavera la Nueva, Toledo)
title: La villa romana de "El Saucedo" (Talavera la Nueva, Toledo)
titleType: Subtitle
Creators: name:  Bendala Galán, Manuel
name: Castelo Ruano, Raquel
name: Arribas Domínguez, Raúl
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: El Saucedo, villa (Talavera la Nueva, Toledo)
subject: Talavera de la Reina
subject: El Saucedo, villa (Talavera la Nueva, Toledo)
subject: Talavera de la Reina
subject: El Saucedo, villa (Talavera la Nueva, Toledo)
subject: Talavera de la Reina

description: Madrider Mitteilungen, Vol. 39 (1998)
description: Folgt.
Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties
Creators: name: Li, Ennian
name: Wang, Kai
name: Zhang, Bei
name: Guo, Siqi
name: Xiao, Senhao
name: Pan, Qi
name: Wang, Xiaowan
name: Chen, Weiying
name: Wu, Yunshan
name: Xu, Hesong
name: Kong, Xiangqian
name: Luo, Cheng
name: Chen, Shijie
name: Liu, Bo
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Virology

description: The DNA methyltransferases (DNMTs) were found in mammals to maintain DNA methylation. Among them, DNMT1 was the first identified, and it is an attractive target for tumour chemotherapy. DC_05 and DC_517 have been reported in our previous work, which is non-nucleoside DNMT1 inhibitor with low micromolar IC50 values and significant selectivity towards other S-adenosyl-L-methionine (SAM)-dependent protein methyltransferases. In this study, through a process of similarity-based analog searching, a series of DNMT1 inhibitors were designed, synthesized, and evaluated as anticancer agents. SAR studies were conducted based on enzymatic assays. And most of the compounds showed strong inhibitory activity on human DNMT1, especially WK-23 displayed a good inhibitory effect on human DNMT1 with an IC50 value of 5.0 µM. Importantly, the pharmacokinetic (PK) profile of WK-23 was obtained with quite satisfying oral bioavailability and elimination half-life. Taken together, WK-23 is worth developing as DNMT1-selective therapy for the treatment of malignant tumour.
Molecular Gas Dominated 50 kpc Ram Pressure Stripped Tail of the Coma Galaxy D100
Creators: name: Jachym, Pavel
name: Sun, Ming
name: Kenney, Jeffrey D. P.
name: Cortese, Luca
name: Combes, Francoise
name: Yagi, Masafumi
name: Yoshida, Michitoshi
name: Palous, Jan
name: Roediger, Elke
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We have discovered large amounts of molecular gas, as traced by CO emission, in the ram pressure stripped gas tail of the Coma cluster galaxy D100 (GMP 2910), out to large distances of about 50 kpc. D100 has a 60 kpc long, strikingly narrow tail which is bright in X-rays and Hα. Our observations with the IRAM 30m telescope reveal in total ~ 10^9 M_sun of H_2 (assuming the standard CO-to-H_2 conversion) in several regions along the tail, thus indicating that molecular gas may dominate its mass. Along the tail we measure a smooth gradient in the radial velocity of the CO emission that is offset to lower values from the more diffuse Hα gas velocities. Such a dynamic separation of phases may be due to their differential acceleration by ram pressure. D100 is likely being stripped at a high orbital velocity >2200 km/s by (nearly) peak ram pressure. Combined effects of ICM viscosity and magnetic fields may be important for the evolution of the stripped ISM. We propose D100 has reached a continuous mode of stripping of dense gas remaining in its nuclear region. D100 is the second known case of an abundant molecular stripped-gas tail, suggesting that conditions in the ICM at the centers of galaxy clusters may be favorable for molecularization. From comparison with other galaxies, we find there is a good correlation between the CO flux and the Hα surface brightness in ram pressure stripped gas tails, over about 2 dex.
description: Accepted for publication to ApJ
Additional file 1: Figures S1 and S2. of Variants of cancer susceptibility genes in Korean BRCA1/2 mutation-negative patients with high risk for hereditary breast cancer
Creators: name: Park, Ji
name: Lee, Seung-Tae
name: Nam, Eun
name: Han, Jung
name: Jung-Yun Lee
name: Jieun Kim
name: Kim, Tae
name: Park, Hyung
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: This file includes the methods detecting pathogenic variants and lage deletion in this study; depth of coverage and method for detection of large insertion-deletion of exon using next-generation sequencing, and confirmation of deleterious mutations using Sanger sequencing or MLPA in four patients. (PDF 1477 kb)
Additional file 4 of Establishment and validation of a prognostic model based on HRR-related lncRNAs in colon adenocarcinoma
Creators: name: Tang, Xingkui
name: Lin, Yukun
name: He, Jialin
name: Luo, Xijun
name: Liang, Junjie
name: Zhu, Xianjun
name: Li, Tao
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Additional file 4: Supplementary Figure 4. HRR-related lncRNAs interaction network construction and pathway enrichment analysis. (A) Interaction network of HRR-related lncRNAs and its target genes. (B) Pathway enrichment analysis.
Gustafson integrals for $SL(2,\mathbb{C})$ spin magnet
Creators: name: Derkachov, S. E.
name: Manashov, A. N.
name: Valinevich, P. A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: It was observed recently that the multidimensional Mellin--Barnes integrals (Gustafson's integrals) arise naturally in studies of the $SL(2,R)$ spin chain models. We extend this analysis to the noncompact $SL(2,\mathbb{C})$ spin magnets and obtain integrals which generalize Gustafson's integrals to the complex case.
description: 11 pages, 2 figures
title: Cerámicas africanas en Munigua y el valle del Guadalquivir
title: Cerámicas africanas en Munigua y el valle del Guadalquivir
titleType: Subtitle
Creators: name: Alonso de la Sierra Fernández, Juan
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Munigua (Villanueva del Río y Minas, Sevilla)
subject: Terra Sigillata Africana
subject: Munigua (Villanueva del Río y Minas, Sevilla)
subject: Terra Sigillata Africana
subject: Munigua (Villanueva del Río y Minas, Sevilla)
subject: Terra Sigillata Africana

description: Madrider Mitteilungen, Vol. 39 (1998)
description: Folgt.
Parent Emotion Regulation, Child Emotion Regulation and Child Depression
Creators: name: Hankin, Benjamin
name: Brandes, Cassandra M
name: Kang, Michelle
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Clinical Psychology
subject: Developmental Psychology
subject: Child Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: Emotion regulation plays a key role in the development of depressive and anxiety symptoms, and family context is an important component of emotion regulation because children's emotion regulation and family influences may affect each other via bidirectional processes. The objective of this project is to explore the unique associations among parent's emotion regulation (ER) strategy use, child's ER strategy use and child depression, along with potential interaction effects of the child's grade and gender. We will also investigate whether parent and child ER strategies are predictive of changes in child’s depression.
title: Miniaturhermen aus Stein : Eine vernachlässigte Gattung kleinformatiger Skulptur der römischen Villeggiatur
title: Miniaturhermen aus Stein : Eine vernachlässigte Gattung kleinformatiger Skulptur der römischen Villeggiatur
titleType: Subtitle
Creators: name: Rückert, Claudia
Publisher: name: Deutsches Archäologisches Institut
Year: 2020

description: Madrider Mitteilungen, Vol. 39 (1998)
description: Deutsche Zusammenfassung folgt.
Carbon Ejection from a SiO2/SiC(0001) Interface by Annealing in High-Purity Ar
Creators: name: Kobayashi, Takuma
name: Kimoto, Tsunenobu
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We found that carbon-associated byproducts formed at the dry-oxidized SiO2/SiC(0001) interface could be decomposed and be taken out to the SiO2 side by high-purity Ar annealing. We evaluated the concentration of the ejected carbon atoms in the SiO2 by secondary ion mass spectrometry, and discovered that it clearly depends on the condition of oxide formation (dry-oxidation, nitridation treatment, and phosphorus treatment). This work provides an indirect but unambiguous evidence for the carbon-byproducts existing at the SiO2/SiC interfaces, and also indicates that the phosphorus treatment removes the carbon-byproducts, leading to significant reduction of interface defects.
description: 13 Pages, 5 figures
Development of novel 9-O-substituted-13-octylberberine derivatives as potential anti-hepatocellular carcinoma agents
Creators: name: Chen, Jichao
name: Duan, Yiping
name: Yu, Xiaoxuan
name: Zhong, Jiarou
name: Bai, Jing
name: Li, Nian-Guang
name: Zhu, Zheying
name: Xu, Jinyi
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Virology

description: A series of novel 9-O-substituted-13-octylberberine derivatives were designed, synthesised and evaluated for their anti-hepatocellular carcinoma (HCC) activities. Compound 6k showed the strongest activity against three human hepatoma cells including HepG2, Sk-Hep-1 and Huh-7 cells with IC50 values from 0.62 to 1.69 μM, which were much superior to berberine (IC50 >50 μM). More importantly, 6k exhibited lower cytotoxicity against normal hepatocytes L-02 with good lipid-water partition properties. The mechanism studies revealed that 6k caused G2/M phase arrest of the cell cycle, stabilised G-quadruplex DNA, and induced apoptosis via a mitochondrial apoptotic pathway. Finally, the in vivo anti-HCC activity of 6k was validated in the H22 liver cancer xenograft mouse model. Collectively, the current study would provide a new insight into the discovery of novel, safe and effective anti-HCC agents.
Synthesis and evaluation of novel 1-(((6-substitutedbenzo[d]thiazol-2-yl)amino)(heteroaryl)methyl)naphthalen-2-ol as pesticidal agents
Creators: name: Shang, Junfeng
name: Li, Yuxin
name: Yang, Na
name: Xiong, Lixia
name: Wang, Baolei
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: To discover new agrochemicals with prominent pesticidal properties, a series of novel β-naphthol derivatives containing benzothiazolylamino and various heteroaryl groups (8a-q) were efficiently synthesised via Betti reaction. The bioassay results showed that most of the synthesised compounds exhibited favourable insecticidal potentials, particularly towards oriental armyworm (50–100% at 200 mg·L−1) and diamondback moth (50–95% at 10 mg·L−1). Compounds 8 b, 8f, 8 g, 8j, 8k, 8n, and 8o possessed LC50 values of 0.0988–5.8864 mg·L−1 against diamondback moth. Compounds 8i, 8 l, and 8 m also displayed lethality rates of 30–90% against spider mite at the concentration of 100 mg·L−1. Overall, some compounds could be considered as new insecticidal/acaricidal leading structures for further investigation. The calcium imaging experiments revealed that 8 h, 8i, and viii could activate the release of calcium ions in insect (M. separata) central neurons at a higher concentration (50 mg·L−1). The SAR analysis provided valuable information for further structural modifications.
Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist: simulation-guided analogue design and pharmacological screening
Creators: name: Agha, Khalid A.
name: Abo-Dya, Nader E.
name: Issahaku, Abdul Rashid
name: Agoni, Clement
name: Soliman, Mahmoud E. S.
name: Abdel-Aal, Eatedal H.
name: Abdel-Samii, Zakaria K.
name: Ibrahim, Tarek S.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Cell Biology
Molecular Biology
Neuroscience
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Developmental Biology

description: An efficient method for synthesising NMDAR co-agonist Sunifiram (DM235), in addition to Sunifram-carbamate and anthranilamide hybrids, has been developed in high yields via protecting group-free stepwise unsymmetric diacylation of piperazine using N-acylbenzotiazole. Compounds 3f, 3d, and 3i exhibited promising nootropic activity by enhancing acetylecholine (ACh) release in A549 cell line. Moreover, the carbamate hybrid 3f was found to exhibit higher in vitro potency than donepezil with IC50 = 18 ± 0.2 nM, 29.9 ± 0.15 nM for 3f and donepezil, respectively. 3f was also found to effectively inhibit AChE activity in rat brain (AChE = 1.266 ng/mL) compared to tacrine (AChE = 1.137 ng/ml). An assessment of the ADMET properties revealed that compounds 3f, 3d, and 3i are drug-like and can penetrate blood–brain barrier. Findings presented here showcase highly potential cholinergic agents, with expected partial agonist activity towards glycine binding pocket of NMDAR which could lead to development and optimisation of novel nootropic drugs.
Additional file 2: Table S1. of High-throughput immunophenotypic characterization of bone marrow- and cord blood-derived mesenchymal stromal cells reveals common and differentially expressed markers: identification of angiotensin-converting enzyme (CD143) as a marker differentially expressed between adult and perinatal tissue sources
Creators: name: Amati, Eliana
name: Perbellini, Omar
name: Rotta, Gianluca
name: Bernardi, Martina
name: Chieregato, Katia
name: Sella, Sabrina
name: Rodeghiero, Francesco
name: Ruggeri, Marco
name: Astori, Giuseppe
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Hematology

description: Mean and CV values of log2 FI for each of 246 investigated markers. (DOCX 22 kb)
title: Zur Bauornamentik des römischen Theaters von Segóbriga
title: Zur Bauornamentik des römischen Theaters von Segóbriga
titleType: Subtitle
Creators: name: Trunk, Markus
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Segobriga (Saelices, Cuenca)
subject: Segobriga (Saelices, Cuenca)

description: Madrider Mitteilungen, Vol. 39 (1998)
description: Deutsche Zusammenfassung folgt.
title: Ein hellenistisch-etruskischer Spiegel vom Morro de Mezquitilla (Algarrobo, Málaga)
title: Ein hellenistisch-etruskischer Spiegel vom Morro de Mezquitilla (Algarrobo, Málaga)
titleType: Subtitle
Creators: name: Mansel, Karin
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Morro de Mezquitilla (Algarrobo, Málaga)
subject: Morro de Mezquitilla (Algarrobo, Málaga)

description: Madrider Mitteilungen, Vol. 39 (1998)
description: Deutsche Zusammenfassung folgt.
Critical Non-Abelian Vortex in Four Dimensions and Little String Theory
Creators: name: Shifman, M.
name: Yung, A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: As was shown recently, non-Abelian vortex strings supported in four-dimensional ${\cal N}=2$ supersymmetric QCD with the U(2) gauge group and $N_f=4$ quark multiplets (flavors) become critical superstrings. In addition to the translational moduli non-Abelian strings under consideration carry six orientational and size moduli. Together they form a ten-dimensional target space required for a superstring to be critical. The target space of the string sigma model is a product of the flat four-dimensional space and a Calabi-Yau non-compact threefold, namely, the conifold. We study closed string states which emerge in four dimensions (4D) and identify them with hadrons of four-dimensional ${\cal N}=2$ QCD. One massless state was found previously: it emerges as a massless hypermultiplet associated with the deformation of the complex structure of the conifold. In this paper we find a number of massive states. To this end we exploit the approach used in LST, "Little String Theory," namely equivalence between the critical string on the conifold and non-critical $c=1$ string with the Liouville field and a compact scalar at the self-dual radius. The states we find carry "baryonic" charge (its definition differs from standard). We interpret them as "monopole necklaces" formed (at strong coupling) by the closed string with confined monopoles attached.
description: 27 pages, 2 figures. arXiv admin note: text overlap with arXiv:1611.03111, arXiv:1605.08433
title: Las producciones cerámicas del alfar vacceo de Cauca (Coca, Segovia)
title: Las producciones cerámicas del alfar vacceo de Cauca (Coca, Segovia)
titleType: Subtitle
Creators: name: Blanco García, Juan Francisco
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Coca (Segovia)
subject: Coca (Segovia)

description: Madrider Mitteilungen, Vol. 39 (1998)
description: Folgt.
Pterostilbene fluorescent probes as potential tools for targeting neurodegeneration in biological applications
Creators: name: Ciccone, Lidia
name: Nencetti, Susanna
name: Marino, Maria
name: Battocchio, Chiara
name: Iucci, Giovanna
name: Venditti, Iole
name: Marsotto, Martina
name: Montalesi, Emiliano
name: Socci, Simone
name: Bargagna, Beatrice
name: Orlandini, Elisabetta
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Virology

description: Several epidemiological studies suggest that a diet rich in fruit and vegetables reduces the incidence of neurodegenerative diseases. Resveratrol (Res) and its dimethylated metabolite, pterostibene (Ptb), have been largely studied for their neuroprotective action. The clinical use of Res is limited because of its rapid metabolism and its poor bioavailability. Ptb with two methoxy groups and one hydroxyl group has a good membrane permeability, metabolic stability and higher in vivo bioavailability in comparison with Res. The metabolism and pharmacokinetics of Ptb are still sparse, probably due to the lack of tools that allow following the Ptb destiny both in living cells and in vivo. In this contest, we propose two Ptb fluorescent derivatives where Ptb has been functionalised by benzofurazan and rhodamine-B-isothiocyanate, compounds 1 and 2, respectively. Here, we report the synthesis, the optical and structural characterisation of 1 and 2, and, their putative cytotoxicity in two different cell lines.
Additional file 1: Figure S1. of High-throughput immunophenotypic characterization of bone marrow- and cord blood-derived mesenchymal stromal cells reveals common and differentially expressed markers: identification of angiotensin-converting enzyme (CD143) as a marker differentially expressed between adult and perinatal tissue sources
Creators: name: Amati, Eliana
name: Perbellini, Omar
name: Rotta, Gianluca
name: Bernardi, Martina
name: Chieregato, Katia
name: Sella, Sabrina
name: Rodeghiero, Francesco
name: Ruggeri, Marco
name: Astori, Giuseppe
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Transformation and selection. a) The log2 transformation of FI was performed to improve the resolution of low FI values. b) The markers with the smallest variability across samples independently from the source were selected according to a CV of log2 FIâ â ¤â 0.5. Accordingly, 59 markers represented below the dotted line were subsequently considered for unsupervised hierarchical cluster analysis. (PDF 439 kb)
Additional file 2 of Gestational systolic blood pressure trajectories and risk of adverse maternal and perinatal outcomes in Chinese women
Creators: name: Teng, Haoyue
name: Wang, Yumei
name: Han, Bing
name: Liu, Jieyu
name: Cao, Yingying
name: Wang, Jiaxiang
name: Zhu, Xiaoyan
name: Fu, Jiaojiao
name: Ling, Qi
name: Xiao, Chengqi
name: Wan, Zhongxiao
name: Yin, Jieyun
Publisher: name: figshare
Year: 2021
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 2: Supplementary Table 1. Latent Class Growth models results. Supplementary Table 2. The associatio Mixture ns of SBP trajectories with adverse maternal outcomes. Supplementary Table 3. The associations of SBP trajectories with adverse fetal outcomes. Supplementary Table 4. Reclassification and Discrimination Statistics of adverse maternal and perinatal outcomes based on SBP trajectory.
Pyrimidine-5-carbonitrile based potential anticancer agents as apoptosis inducers through PI3K/AKT axis inhibition in leukaemia K562
Creators: name: El-Dydamony, Nehad M.
name: Abdelnaby, Rana M.
name: Abdelhady, Rasha
name: Ali, Omaima
name: Fahmy, Mohamed I.
name: Eldeen, Rasha R. Fakhr
name: Helwa, Amira A.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Developmental Biology
Cancer
Hematology

description: A novel series of 4-(4-Methoxyphenyl)-2-(methylthio)pyrimidine-5-carbonitrile was developed linked to an aromatic moiety via N-containing bridge and then evaluated for their cytotoxic activity against MCF-7 and K562 cell lines. Seven compounds exhibited the highest activity against both cell lines where compounds 4d and 7f were the most active against K562 cell line. Exploring their molecular mechanisms by enzyme inhibition assay on PI3Kδ/γ and AKT-1 showed that compound 7f was promising more than 4d with IC50 = 6.99 ± 0.36, 4.01 ± 0.55, and 3.36 ± 0.17 uM, respectively. Also, flowcytometric analysis revealed that 7f caused cell cycle arrest at S-phase followed by caspase 3 dependent apoptosis induction. Mechanistically, compound 7f proved to modulate the expression of PI3K, p-PI3K, AKT, p-AKT, Cyclin D1, and NFΚβ. Furthermore, in-vivo toxicity study indicated good safety profile for 7f. These findings suggest that the trimethoxy derivative 7f has strong potential as a multi-acting inhibitor on PI3K/AKT axis targeting breast cancer and leukaemia.
Central and peripheral vision for scene recognition: A neurocomputational modeling exploration
Creators: name: Wang, Panqu
name: Cottrell, Garrison W.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences

description: What are the roles of central and peripheral vision in human scene recognition? Larson and Loschky (2009) showed that peripheral vision contributes more than central vision in obtaining maximum scene recognition accuracy. However, central vision is more efficient for scene recognition than peripheral, based on the amount of visual area needed for accurate recognition. In this study, we model and explain the results of Larson and Loschky (2009) using a neurocomputational modeling approach. We show that the advantage of peripheral vision in scene recognition, as well as the efficiency advantage for central vision, can be replicated using state-of-the-art deep neural network models. In addition, we propose and provide support for the hypothesis that the peripheral advantage comes from the inherent usefulness of peripheral features. This result is consistent with data presented by Thibaut, Tran, Szaffarczyk, and Boucart (2014), who showed that patients with central vision loss can still categorize natural scenes efficiently. Furthermore, by using a deep mixture-of-experts model ("The Deep Model," or TDM) that receives central and peripheral visual information on separate channels simultaneously, we show that the peripheral advantage emerges naturally in the learning process: When trained to categorize scenes, the model weights the peripheral pathway more than the central pathway. As we have seen in our previous modeling work, learning creates a transform that spreads different scene categories into different regions in representational space. Finally, we visualize the features for the two pathways, and find that different preferences for scene categories emerge for the two pathways during the training process.
description: http://jov.arvojournals.org/Article.aspx?articleid=2623232
Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents
Creators: name: Du, Kangjia
name: Ma, Wantong
name: Yang, Chengjie
name: Zhou, Zhongkun
name: Hu, Shujian
name: Tian, Yanan
name: Zhang, Hao
name: Ma, Yunhao
name: Jiang, Xinrong
name: Zhu, Hongmei
name: Liu, Huanxiang
name: Chen, Peng
name: Liu, Yingqian
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: A series of novel derivatives of isaindigotone, which comes from the root of isaits indinatca Fort, were synthesised (Compound 1–26). Four human gastrointestinal cancer cells (HCT116, PANC-1, SMMC-7721, and AGS) were employed to evaluate the anti-proliferative activity. Among them, Compound 6 displayed the most effective inhibitory activity on AGS cells with an IC50 (50% inhibitory concentration) value of 2.2 μM. The potential mechanism study suggested that Compound 6 induced apoptosis in AGS cells. The collapse of mitochondrial membrane potential (MMP) in AGS cells was proved. In docking analysis, good affinity interaction between Compound 6 and AKT1 was discovered. Treatment of AGS cells with Compound 6 also resulted in significant suppression of PI3K/AKT/mTOR signal pathway. The collapse of MMP and suppression of PI3K/AKT/mTOR signal pathway may be responsible for induction of apoptosis. This derivative Compound 6 could be useful as an underlying anti-tumour agent for treatment of gastric cancer.
The kinematic Sunyaev-Zel'dovich effect of the large-scale structure (I): dependence on neutrino mass
Creators: name: Roncarelli, Mauro
name: Villaescusa-Navarro, Francisco
name: Baldi, Marco
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The study of neutrinos in astrophysics requires the combination of different observational probes. The temperature anisotropies of the cosmic microwave background induced via the kinematic Sunyaev-Zel'dovich (kSZ) effect may provide interesting information since they are expected to receive significant contribution from high-redshift plasma. We present a set of cosmological hydrodynamical simulations that include a treatment of the neutrino component considering four different sum of neutrino masses: $Σm_ν=(0,0.15,0.3,0.6)$ eV. Using their outputs, we modelled the kSZ effect due to the large-scale structure after the reionization by producing mock maps, then computed the kSZ power spectrum and studied how it depends on $z_{\rm re}$ and $Σm_ν$. We also run a set of four simulations to study and correct possible systematics due to resolution, finite box size and astrophysics. With massless neutrinos we obtain $\mathcal{D}^{\rm kSZ}_{3000}=4.0$ $μ{\rm K}^2$ ($z_{\rm re}$=8.8), enough to account for all of the kSZ signal of $\mathcal{D}^{\rm kSZ}_{3000}=(2.9\pm1.3)$ $μ{\rm K}^2$ measured with the South Pole Telescope. This translates into an upper limit on the kSZ effect due to patchy reionization of $\mathcal{D}^{\rm kSZ,patchy}_{3000}<1.0$ $μ{\rm K}^2$ (95 per cent confidence level). Massive neutrinos induce a damping of kSZ effect power of about 8, 12 and 40 per cent for $Σm_ν=(0.15,0.3,0.6)$ eV, respectively. We study the dependence of the kSZ signal with $z_{\rm re}$ and the neutrino mass fraction, $f_ν$, and obtain $\mathcal{D}^{\rm kSZ}_{3000}\propto z_{\rm re}^{0.26}(1-f_ν)^{14.3}$. Interestingly, the scaling with $f_ν$ is significantly shallower with respect to the equivalent thermal SZ effect, and may be used to break the degeneracy with other cosmological parameters.
description: 11 pages, 7 figures, 2 tables. Accepted for publication in MNRAS
Additional file 1 of Gestational systolic blood pressure trajectories and risk of adverse maternal and perinatal outcomes in Chinese women
Creators: name: Teng, Haoyue
name: Wang, Yumei
name: Han, Bing
name: Liu, Jieyu
name: Cao, Yingying
name: Wang, Jiaxiang
name: Zhu, Xiaoyan
name: Fu, Jiaojiao
name: Ling, Qi
name: Xiao, Chengqi
name: Wan, Zhongxiao
name: Yin, Jieyun
Publisher: name: figshare
Year: 2021
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 1: Supplementary Fig. 1. Gestational SBP trajectories from 10 to 40 gestational weeks if participants with ≥2 records were included.