cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Aggression Toward Others Misdiagnosed as Primary Tics
Creators: name: Kurvits, Lille
name: Mainka, Tina
name: Cavanna, Andrea E.
name: Kühn, Andrea A.
name: Ganos, Christos
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: allo-aggression
subject: tic disorders
subject: Tourette syndrome
subject: functional neurological symptom disorder
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Tics describe a wide range of sudden and repetitive behaviors. Their multifaceted clinical features may resemble other explosive behaviors, including repetitive episodes of aggression toward others (allo-aggression) reported by subjects without tics. Here, we document 3 exemplary cases that help disentangle allo-aggressive behaviors from tics. Cases: We report 3 cases who presented with an array of complex repetitive behaviors, most notably allo-aggression (eg, sudden kicking, hitting, slapping and biting others, or pushing someone off a bike), which were misdiagnosed as primary tics. In all cases, additional symptoms, such as blackouts, feeling of being controlled by different personalities, or being empowered by repetitive behaviors, and examination pointed toward different neuropsychiatric diagnoses. Conclusions: Repetitive allo-aggressive behaviors are not part of the range of motor manifestations of tics. This observation not only has important medico-legal implications but is also relevant for the overall perception of Tourette syndrome and other primary tic disorders.
The need to make it clear: reconstruct the terminology concerning pain descriptors and pain mechanisms. A scoping review
Creators: name: Margelli, Michele
name: Laghezza, Giulia
name: Cesaretti, Mattia
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Neuroscience and Neurobiology
subject: Kinesiotherapy
subject: Physical Therapy
subject: Physiotherapy
subject: Medicine and Health Sciences
subject: Rehabilitation and Therapy
subject: Life Sciences
subject: Protocol
subject: Pain descriptors
subject: Scoping Review
subject: Pain
subject: Pain mechanisms
subject: Chronic pain

description: Background: Musculoskeletal pain has a significant impact on people’s standard of living; it results in difficulties in sleeping through the night, fatigue, depression, restriction of activities and participation. This kind of pain is (usually) experienced by most of the global population, with a prevalence of 37% in Europe, and all age groups are affected. This kind of pain frequently leads to a chronicity condition. Besides the pain descriptors, in literature there’s a remarkable disagreement about pain terminology, especially there seems to be no connection between the terms that are adopted for clinical descriptors and the terms that can also have, at the same time, the same meaning to represent the pathophysiological mechanism that evokes the pain symptoms. In light of this, the question that came up is: “In scientific literature, what are the terms used as clinical descriptors and which one of those are used to describe pathophysiological mechanisms underlying pain?” As a second objective, this paper’s aim is to propose shareable specific terms interpreted as clinical descriptors, but that can also be attributable to underlying mechanisms driving pain”.
Role of Start-ups in Building Atma Nirbhar Bharat
Creators: name: Sudeep B Chandramana
name: Thomas, Tom K
Publisher: name: figshare
Year: 2020
Subjects: subject: 130203 Economics, Business and Management Curriculum and Pedagogy
subject: FOS: Educational sciences
subject: 150314 Small Business Management
subject: FOS: Economics and business
subject: 150304 Entrepreneurship

description: Ever since the COVID-19 pandemic began in March 2020, the world’s economy has been in tatters due to the resulting health and economic shocks. To deal with the pandemic, countries around the world imposed strict lockdowns on the movement of people, on international travel, and on the transportation of goods and services to minimize the threat to health and safety. This has resulted in many industries and organizations either being shut down or operating at minimum capacity, and the effects are visible globally. To address the economic challenge, on 12th May India’s Prime Minister, in his Atma Nirbhar Bharat Abhiyan (Self-reliant India Campaign), announced an overall economic package worth ₹20 lakh crore (US$280 billion),10% of India's GDP, with emphasis on making India as a self-reliant nation. This paper analyses the role of start-up initiatives and innovative projects in building a self-reliant India. The study further assesses how this mission can help the micro, small and medium enterprises (MSME) in establishing their business. It also provides a few caselets of successful start-ups in India.
Safe procedures despite ultra low radiation doses during catheter ablations of atrial and ventricular arrhythmias—A multicenter experience
Creators: name: Attanasio, Philipp
name: Huemer, Martin
name: Kaehler, Nora
name: Keller, Theresa
name: Schreiber, Tobias
name: Niehues, Reinhard
name: Katsani‐Potempa, Dimitra
name: Klein, Rolf Michael
name: Landmesser, Ulf
name: Deisenhofer, Isabel
name: Tutdibi, Osman
name: Bourier, Felix
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: ablation therapy
subject: antiscatter grid
subject: framerate reduction
subject: radiation dose
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Introduction: Despite the development of non-fluoroscopic catheter visualization options, fluoroscopy is still used in most ablation procedures. The aim of this multicenter study was to evaluate the safety and efficacy of a new ultra-low dose radiation protocol for EP procedures in a large number of patients. Methods and results: A total of 3462 consecutive patients (male 1926 (55.6%), age 64.4 ± 14.0 years, BMI 26.65 ± 4.70) undergoing radiofrequency ablation (left atrial (n = 2316 [66.9%], right atrial (n = 675 [19.5%], or ventricular (n = 471 [13.6%]) in three German centers were included in the analysis. Procedures were performed using a new ultra-low dose protocol operating at 8nGy for fluoroscopy and 36nGy for cine-loops. Additionally a very low framerate (2-3FPS) was used. Using the new protocol very low Air kerma-area product (KAP) values were achieved for left atrial ablations (104.25 ± 84.22 μGym2 ), right atrial ablations (70.98 ± 94.79 μGym2 ) and ablations for ventricular tachycardias or PVCs (78.62 ± 66.59 μGym2 ). Acute procedural success was achieved in 3289/3388 (97.1%) while the rate of major complications was very low compared to previously published studies not using low dose settings (n = 20, 0.6%). Conclusion: The ultra-low dose, low framerate protocol leads to very low radiation doses for all EP procedures while neither procedural time, fluoroscopy time nor success or complication rates were compromised. When compared to current real-world Air KAP data the new ultra-low dose fluoroscopy protocol reduces radiation exposure by more than 90%.
Hierarchical phylogenetic community assembly of soil protists in a temperate agricultural field
Creators: name: Roy, Julien
name: Mazel, Florent
name: Dumack, Kenneth
name: Bonkowski, Michael
name: Rillig, Matthias C.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: soil
subject: protists
subject: community assembly
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Protists are abundant, diverse and perform essential functions in soils. Protistan community structure and its change across time or space are traditionally studied at the species level but the relative importance of the processes shaping these patterns depends on the taxon phylogenetic resolution. Using 18S rDNA amplicon data of the Cercozoa, a group of dominant soil protists, from an agricultural field in western Germany, we observed a turnover of relatively closely related taxa (from sequence variants to genus‐level clades) across soil depth; while across soil habitats (rhizosphere, bulk soil, drilosphere), we observed turnover of relatively distantly related taxa, confirming Paracercomonadidae as a rhizosphere‐associated clade. We extended our approach to show that closely related Cercozoa encounter divergent arbuscular mycorrhizal (AM) fungi across soil depth and that distantly related Cercozoa encounter closely related AM fungi across soil compartments. This study suggests that soil Cercozoa community assembly at the field scale is driven by niche‐based processes shaped by evolutionary legacy of adaptation to conditions primarily related to the soil compartment, followed by the soil layer, giving a deeper understanding on the selection pressures that shaped their evolution.
title: Ilias; [um 1475-1500]
title: (Prosaversion – Laurentius Valla, Franciscus Griffolinus)
titleType: Subtitle
Creators: name: Homerus
name: Valla, Lorenzo
name: Griffolini, Francesco
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2009

description: Entstehungsort: Neapel. - Entstehungszeit: 1475-1500
Holographic scattering and non-minimal RT surfaces
Creators: name: Caminiti, Jacqueline
name: Friedman-Shaw, Batia
name: May, Alex
name: Myers, Robert C.
name: Papadoulaki, Olga
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In the AdS/CFT correspondence, the causal structure of the bulk AdS spacetime is tied to entanglement in the dual CFT. This relationship is captured by the connected wedge theorem, which states that a bulk scattering process implies the existence of $O(1/G_N)$ entanglement between associated boundary subregions. In this paper, we study the connected wedge theorem in two asymptotically AdS$_{2+1}$ spacetimes: the conical defect and BTZ black hole geometries. In these settings, we find that bulk scattering processes require not just large entanglement, but also additional restrictions related to candidate RT surfaces which are non-minimal. We argue these extra relationships imply a certain CFT entanglement structure involving internal degrees of freedom. Because bulk scattering relies on sub-AdS scale physics, this supports the idea that sub-AdS scale locality emerges from internal degrees of freedom. While the new restriction that we identify on non-minimal surfaces is stronger than the initial statement of the connected wedge theorem, we find that it is necessary but still not sufficient to imply bulk scattering in mixed states.
description: 56 pages, 28 figures
Inflammation, fibrosis and skeletal muscle regeneration in LGMDR9 are orchestrated by macrophages
Creators: name: Kölbel, Heike
name: Preuße, Corinna
name: Brand, Lukas
name: Moers, Arpad Von
name: Della Marina, Adela
name: Schuelke, Markus
name: Roos, Andreas
name: Goebel, Hans‐Hilmar
name: Schara‐Schmidt, Ulrike
name: Stenzel, Werner
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: alpha dystroglycan
subject: CD206
subject: fibrosis
subject: inflammation
subject: LGMDR9
subject: macrophages
subject: regeneration
subject: VEGF
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Aims: Variable degrees of inflammation, necrosis, regeneration and fibrofatty replacement are part of the pathological spectrum of the dystrophic process in alpha dystroglycanopathy LGMDR9 (FKRP-related, OMIM #607155), one of the most prevailing types of LGMDs worldwide. Inflammatory processes and their complex interplay with vascular, myogenic and mesenchymal cells may have a major impact on disease development. The purpose of our study is to describe the specific immune morphological features in muscle tissue of patients with LGMDR9 to enable a better understanding of the phenotype of muscle damage leading to disease progression. Methods: We have analysed skeletal muscle biopsies of 17 patients genetically confirmed as having LGMDR9 by histopathological and molecular techniques. Results: We identified CD206+ MHC class II+ and STAT6+ immune-repressed macrophages dominating the endomysial infiltrate in areas of myofibre regeneration and fibrosis. Additionally, PDGFRβ+ pericytes were located around MHC class II+ activated capillaries residing in close proximity to areas of fibrosis and regenerating fibres. Expression of VEGF was found on many regenerating neonatal myosin+ fibres, myofibres and CD206+ macrophages also co-expressed VEGF. Conclusion: Our results show characteristic immune inflammatory features in LGMDR9 and more specifically shed light on the predominant role of macrophages and their function in vascular organisation, fibrosis and myogenesis. Understanding disease-specific immune phenomena potentially inform about possibilities for anti-fibrotic and anti-inflammatory therapeutic strategies, which may complement Ribitol replacement and gene therapies for LGMDR9 that may be available in the future.
Holography, Entanglement Entropy, and Conformal Field Theories with Boundaries or Defects
Creators: name: Jensen, Kristan
name: O'Bannon, Andy
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study entanglement entropy (EE) in conformal field theories (CFTs) in Minkowski space with a planar boundary or with a planar defect of any codimension. In any such boundary CFT (BCFT) or defect CFT (DCFT), we consider the reduced density matrix and associated EE obtained by tracing over the degrees of freedom outside of a (hemi-)sphere centered on the boundary or defect. Following Casini, Huerta, and Myers, we map the reduced density matrix to a thermal density matrix of the same theory on hyperbolic space. The EE maps to the thermal entropy of the theory on hyperbolic space. For BCFTs and DCFTs dual holographically to Einstein gravity theories, the thermal entropy is equivalent to the Bekenstein-Hawking entropy of a hyperbolic black brane. We show that the horizon of the hyperbolic black brane coincides with the minimal area surface used in Ryu and Takayanagi's conjecture for the holographic calculation of EE. We thus prove their conjecture in these cases. We use our results to compute the Rényi entropies and EE in DCFTs in which the defect corresponds to a probe brane in a holographic dual.
description: 47 pages plus appendices, 2 figures. arXiv admin note: figure 1 is taken from arXiv:hep-th/0303249
Differentialrechnung. Analytische Funktionen mehrerer Variabeln, Vorlesungen von Adolf Hurwitz.
Notizen unter dem Titel "Differenzial-Rechnung", Beginn datiert mit 1.5.1884, ausgearbeitet von Adolf Hurwitz.
Notizen unter dem Titel "Analyt. Funktionen mehrerer Variabeln", Beginn datiert mit 6.5.1884, ausgearbeitet von Adolf Hurwitz
Creators: name: Hurwitz, Adolf
Publisher: name: [s.n.]
Year: 1884

description: Notizen zu zwei Vorlesungen (1.5.1884-31.7.1884, 41 Bl.; 6.5.1884-26.7.1884, 19 Bl.), vorgetragen im Sommersemester 1884 an der Albertus-Universität Königsberg.
Texte mit Figuren.
Abschliessend 2 Bl. leer.
Beilage: Notizen, gefaltet (Inhalt z.T. doppelt digitalisiert hinsichtlich Nachvollzug der möglichen Abfolge)
Reconstructing the Magnetic Field in an Arbitrary Domain via Data-driven Bayesian Methods and Numerical Simulations
Creators: name: Pavlou, Georgios E.
name: Pavlidou, Vasiliki
name: Harmandaris, Vagelis
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computational Physics (physics.comp-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Numerical Analysis (math.NA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Inverse problems are prevalent in numerous scientific and engineering disciplines, where the objective is to determine unknown parameters within a physical system using indirect measurements or observations. The inherent challenge lies in deducing the most probable parameter values that align with the collected data. This study introduces an algorithm for reconstructing parameters by addressing an inverse problem formulated through differential equations underpinned by uncertain boundary conditions or variant parameters. We adopt a Bayesian approach for parameter inference, delineating the establishment of prior, likelihood, and posterior distributions, and the subsequent resolution of the maximum a posteriori problem via numerical optimization techniques. The proposed algorithm is applied to the task of magnetic field reconstruction within a conical domain, demonstrating precise recovery of the true parameter values.
description: 28 pages, 11 figures
Online Advanced Labs in Physics
Creators: name: Bennett, Peter A.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: At Arizona State University we have built the first and only fully online Bachelor of Science degree in Physics, with a complete curriculum, including labs. The upper division Advanced Lab courses present a special challenge for online delivery. We address that using a set of custom-built simulator modules that replicate all the imperfections (noise, background, etc) inherent in real-world data. The set of experiments duplicates those of the in-person classes. In this paper, we present an overview of these labs and discuss the advantages and challenges of delivering them online. We assert that these labs provide a valid and rigorous component for the fully online degree. The entire set of labs is available as Open Source Supplemental Materials and is shared for others to use in part or in whole, with suitable attribution.
description: 16 pages, 4 figures. Accepted, American Journal of Physics
Cold gas dynamics in Hydra-A: evidence for a rotating disk
Creators: name: Hamer, S. L.
name: Edge, A. C.
name: Swinbank, A. M.
name: Oonk, J. B. R.
name: Mittal, R.
name: McNamara, B. R.
name: Russell, H. R.
name: Bremer, M. N.
name: Combes, F.
name: Fabian, A. C.
name: Nesvadba, N. P. H.
name: O'Dea, C. P.
name: Baum, S. A.
name: Salomé, P.
name: Tremblay, G.
name: Donahue, M.
name: Ferland, G. J.
name: Sarazin, C. L.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present multi-frequency observations of the radio galaxy Hydra-A (3C218) located in the core of a massive, X-ray luminous galaxy cluster. IFU spectroscopy is used to trace the kinematics of the ionised and warm molecular hydrogen which are consistent with a ~ 5 kpc rotating disc. Broad, double-peaked lines of CO(2-1), [CII]157 $μ$m and [OI]63 $μ$m are detected. We estimate the mass of the cold gas within the disc to be M$_{gas}$ = 2.3 $\pm$ 0.3 x 10$^9$ M$_{\odot}$. These observations demonstrate that the complex line profiles found in the cold atomic and molecular gas are related to the rotating disc or ring of gas. Finally, an HST image of the galaxy shows that this gas disc contains a substantial mass of dust. The large gas mass, SFR and kinematics are consistent with the levels of gas cooling from the ICM. We conclude that the cold gas originates from the continual quiescent accumulation of cooled ICM gas. The rotation is in a plane perpendicular to the projected orientation of the radio jets and ICM cavities hinting at a possible connection between the kpc-scale cooling gas and the accretion of material onto the black hole. We discuss the implications of these observations for models of cold accretion, AGN feedback and cooling flows.
description: Accepted for publication in MNRAS on October 9 2013
Matei Chihaia / Jesús Guillermo Ferrer Ortega / Sergio Pérez-Gatica / Niklas Schmich, eds. (2023). Caminos cruzados. Filosofía y literatura del exilio español en América Latina
Creators: name: Maeding, Linda
Publisher: name: Estudios Culturales Hispánicos
Year: 2024

description: Reseña
description: Estudios Culturales Hispánicos, Núm. 6 (2024)
Modelling concrete and abstract concepts using brain-constrained deep neural networks
Creators: name: Henningsen-Schomers, Malte R.
name: Pulvermüller, Friedemann
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: neurocomputational modelling experiment
subject: neurobiologically constrained deep neural network
subject: neurobiological theories of semantic representation
subject: 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie

description: A neurobiologically constrained deep neural network mimicking cortical areas relevant for sensorimotor, linguistic and conceptual processing was used to investigate the putative biological mechanisms underlying conceptual category formation and semantic feature extraction. Networks were trained to learn neural patterns representing specific objects and actions relevant to semantically ‘ground’ concrete and abstract concepts. Grounding sets consisted of three grounding patterns with neurons representing specific perceptual or action-related features; neurons were either unique to one pattern or shared between patterns of the same set. Concrete categories were modelled as pattern triplets overlapping in their ‘shared neurons’, thus implementing semantic feature sharing of all instances of a category. In contrast, abstract concepts had partially shared feature neurons common to only pairs of category instances, thus, exhibiting family resemblance, but lacking full feature overlap. Stimulation with concrete and abstract conceptual patterns and biologically realistic unsupervised learning caused formation of strongly connected cell assemblies (CAs) specific to individual grounding patterns, whose neurons were spread out across all areas of the deep network. After learning, the shared neurons of the instances of concrete concepts were more prominent in central areas when compared with peripheral sensorimotor ones, whereas for abstract concepts the converse pattern of results was observed, with central areas exhibiting relatively fewer neurons shared between pairs of category members. We interpret these results in light of the current knowledge about the relative difficulty children show when learning abstract words. Implications for future neurocomputational modelling experiments as well as neurobiological theories of semantic representation are discussed.
Moiré Tuning of Spin Excitations: Individual Fe Atoms on MoS2/Au(111)
Creators: name: Trishin, Sergey
name: Lotze, Christian
name: Bogdanoff, Nils
name: Oppen, Felix Von
name: Franke, Katharina J.
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: Electronic structure
subject: Kondo effect
subject: Magnetic anisotropy
subject: Surfaces
subject: Scanning tunneling microscopy
subject: Scanning tunneling spectroscopy
subject: 500 Naturwissenschaften und Mathematik::530 Physik::539 Moderne Physik

description: Magnetic adatoms on properly designed surfaces constitute exquisite systems for addressing, controlling, and manipulating single quantum spins. Here, we show that monolayers of MoS2 on a Au(111) surface provide a versatile platform for controllably tuning the coupling between adatom spins and substrate electrons. Even for equivalent adsorption sites with respect to the atomic MoS2 lattice, we observe that Fe adatoms exhibit behaviors ranging from pure spin excitations, characteristic of negligible exchange and dominant single-ion anisotropy, to a fully developed Kondo resonance, indicating strong exchange and negligible single-ion anisotropy. This tunability emerges from a moiré structure of MoS2 on Au(111) in conjunction with pronounced many-body renormalizations. We also find striking spectral variations in the immediate vicinity of the Fe atoms, which we explain by quantum interference reflecting the formation of Fe-S hybrid states despite the nominally inert nature of the substrate. Our work establishes monolayer MoS2 as a tuning layer for adjusting the quantum spin properties over an extraordinarily broad parameter range. The considerable variability can be exploited for quantum spin manipulations.
Observation of superconducting pair density modulation within lattice unit cell
Creators: name: Wei, Tianheng
name: Liu, Yanzhao
name: Ren, Wei
name: Liang, Zhen
name: Wang, Ziqiang
name: Wang, Jian
Publisher: name: arXiv
Year: 2024
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In unconventional high-temperature (high-Tc) superconductors, the pair density wave state, an exotic superconducting order showing spatially periodic order parameter modulations with the period of several unit cells and translational symmetry breaking, has attracted broad attention. However, the superconducting pair density modulation within a single unit cell (PDM) has never been carefully investigated before. Here, using scanning tunneling microscopy/spectroscopy, we report the observation of PDM in monolayer high-Tc iron chalcogenide films epitaxially grown on SrTiO3(001). The superconductivity modulations are characterized by the superconducting gap size and the coherence peak sharpness. Further analysis shows that the local maxima and minima in the superconducting gap modulation are centered at the crystallographic locations of the chalcogen atoms, revealing the breaking of the glide-mirror symmetry of the chalcogen atoms in monolayer high-Tc iron chalcogenide films grown on SrTiO3(001). Our findings provide precise microscopic information on superconductivity within the lattice unit cell and may promote the understanding of unconventional high-Tc superconductivity.
title: Role of lipopolysaccharide in membrane-active-peptide interactions with cells as probed by whole-cell deuterium NMR
Creators: name: Kumari, Sarika
Publisher: name: Memorial University of Newfoundland
Year: 2023

description: The increasing appearance of multidrug-resistant pathogens has created an urgent need for suitable alternatives to current antibiotics. Antimicrobial peptides (AMPs), which act as defensive weapons against microbes, have shown great promise because bacteria develop no or low resistance to AMPs. However, only a few antimicrobial peptides are clinically available for clinical use. Understanding how non-phospholipid components of bacteria affect antimicrobial peptide-induced membrane disruption is important for a comprehensive understanding of AMP mechanisms and informing AMP-based drug development. Therefore, the main aim of this thesis was to investigate how lipopolysaccharide (LPS) affects membrane disruption by the AMP MSI-78 and compare the results to the effect of TP2, a cell-penetrating peptide that crosses membrane bilayers without permeabilizing them. We destabilize the LPS layer of Escherichia coli (E. coli) cells via chelation of the stabilizing divalent cations. ²H NMR observations of membrane-deuterated E. coli demonstrate that an ethylenediaminetetraacetic acid (EDTA) concentration of 9.0 mM alone has a minor effect on lipid acyl chain order. Interestingly, we find that E. coli pretreated with 9.0 mM EDTA are more sensitive to AMP-induced acyl chain disruption resulting from subsequent treatment with the AMP MSI-78. This indicates that LPS protects E. coli from membrane disruption caused by MSI-78. Surprisingly, we also found that at the level of 2H-NMR, the peptide-induced acyl chain disruptions are similar for MSI-78 and CPP-TP2, although MSI-78 permeabilizes the bilayer and TP2 does not. Furthermore, having intact LPS appears to sensitize the bacteria to TP2, in contrast to intact LPS’ ability to protect bacteria from MSI-78. I also provide some information about AMP selectivity by examining whether non-bacterial cells, i.e., mammalian cells, can compete with bacteria for AMP binding in a mixture of bacteria and mammalian cells. Interestingly, our preliminary data shows that when the MSI-78 was added to the mixture of cells, i.e., membrane-deuterated E. coli and Ramos cells, the presence of Ramos cells slightly reduced the amount of MSI-78 available to interact with the E. coli. Presumably due to some binding of MSI-78 by the Ramos cells. Overall, we show here that LPS, present in bacteria but not model membranes, protects bacteria to some extent from the AMP MSI-78. LPS protection from AMP membrane permeabilization would explain why model lipid bilayers are more prone to permeabilization by AMP than are bilayers in whole bacteria. In addition, since efforts to optimize AMPs as drugs often rely solely on optimizing the AMP’s lipid-permeabilizing activities, consideration of other interactions like AMP-LPS interactions may prove helpful in AMP-based drug design.
Properties of the complementarity set for the cone of copositive matrices
Creators: name: Kostyukova, O. I.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 49N15, 90C25, 90C33, 90C46

description: For a proper cone $K$ and its dual cone $K^*$ in $\mathbb R^n$, the complementarity set of $K$ is defined as
 ${\mathbb C}(K)=\{(x,y): x\in K,\; y\in K^*,\, x^\top y=0\}$. It is known that ${\mathbb C}(K)$ is an $n$-dimensional manifold in the space $\mathbb R^{2n}$. If $ K$ is a symmetric cone, points in ${\mathbb C}(K)$ must satisfy at least $n$ linearly independent bi-linear identities. Since this knowledge comes in handy when optimizing over such cones, it makes sense to search for similar relationships for non-symmetric cones.
 In this paper, we study properties of the complementarity set for the dual cones of copositive and completely positive matrices. Despite these cones are of great interest due to their applications in optimization, they have not yet been sufficiently studied.
description: 26 pages
Viscous flow past a translating body with oscillating boundary
Creators: name: Eiter, Thomas
name: Shibata, Yoshihiro
Publisher: name: Weierstrass Institute
Year: 2023
Subjects: subject: Time-periodic solutions
subject: moving boundary
subject: exterior domain
subject: maximal regularity
subject: spatial decay
subject: 35B40
subject: 35Q30
subject: 35R37
subject: 76D05
subject: 76D07

description: We study an incompressible viscous flow around an obstacle with an oscillating boundary that moves by a translational periodic motion, and we show existence of strong time-periodic solutions for small data in different configurations: If the mean velocity of the body is zero, existence of time-periodic solutions is provided within a framework of Sobolev functions with isotropic pointwise decay. If the mean velocity is non-zero, this framework can be adapted, but the spatial behavior of flow requires a setting of anisotropically weighted spaces. In the latter case, we also establish existence of solutions within an alternative framework of homogeneous Sobolev spaces. These results are based on the time-periodic maximal regularity of the associated linearizations, which is derived from suitable R-bounds for the Stokes and Oseen resolvent problems. The pointwise estimates are deduced from the associated time-periodic fundamental solutions.
A direct relation between confinement and chiral symmetry breaking in temporally odd-number lattice QCD
Creators: name: Doi, Takahiro M.
name: Suganuma, Hideo
name: Iritani, Takumi
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In the lattice QCD formalism, we derive a gauge-invariant analytical relation connecting the Polyakov loop and the Dirac modes on a temporally odd-number lattice, where the temporal lattice size is odd, with the normal (nontwisted) periodic boundary condition. This analytical relation indicates that low-lying Dirac modes have little contribution to the Polyakov loop. Using lattice QCD simulations, we numerically confirm the analytical relation and the negligible contribution of low-lying Dirac modes to the Polyakov loop at the quenched level, i.e., the Polyakov loop is almost unchanged by removing low-lying Dirac-mode contribution from the QCD vacuum generated by lattice QCD in both confinement and deconfinement phases. Thus, we conclude that there is no one-to-one correspondence between confinement and chiral symmetry breaking in QCD. As a new method, modifying the Kogut-Susskind formalism, we develop a method for spin-diagonalizing the Dirac operator on the temporally odd-number lattice.
description: 7 pages, proceeding of Lattice 2013
India on the Move: An Appraisal of Indian Tyre Industry
Creators: name: Sudeep B Chandramana
name: Aleena Sara John
Publisher: name: figshare
Year: 2020
Subjects: subject: 150703 Road Transportation and Freight Services
subject: FOS: Economics and business
subject: 130203 Economics, Business and Management Curriculum and Pedagogy
subject: FOS: Educational sciences
subject: 150309 Logistics and Supply Chain Management

description: After China, Europe, and the United States, India is the fourth largest market for tyres in the world. Tyres manufactured in Indian are being exported to more than 100 countries in the world, including the most astute regions such as US and European nations. Covid-19 has pressed a reset button for all the businesses. It began as a health emergency, but has transmuted into an existential crisis for most of the industries. There is no doubt, the formats for doing businesses would change. Being a progressive sector of Indian manufacturing, tyre industry is riding the waves of change. New concepts such as contactless services are already being implemented as a measure of safety. While the global supply chain addresses the disruptions that the pandemic has caused, Indian tyre industry has the potential to lead in manufacturing at a global level, taking into consideration of the policy changes related to Prime Minister’s call to build a self-reliant India. This paper explores the current status of tyre industry, factors that contribute to higher productivity in the industry, challenges faced by it and the prospects of the industry in moving towards ‘Atmanirbhar Bharat’.
Examining current practice for the analysis and reporting of harm outcomes in phase II and III pharmacology trials: exploring methods to facilitate improved detection of adverse drug reactions
Creators: name: Phillips, Rachel
Publisher: name: Imperial College London
Year: 2021

description: Introduction Randomised controlled trials (RCTs) provide data to help establish the harm-profile of drugs but evidence suggests that this data is underutilised and analysis practices are suboptimal. Aims To develop and assess methods for the analysis and presentation of harm outcomes in phase II/III drug trials that can facilitate the detection of adverse drug reactions (ADRs) and enable communication of informative harm-profiles.Methods A systematic review looked at current practice for collection, analysis and reporting of harm outcomes and a scoping review to identify statistical methods proposed for their analysis was undertaken. A survey of clinical trial statisticians measured awareness of methods for the analysis of harm outcomes, barriers to their use and opinions on solutions to improve practice. Alternative strategies for analysis and presentation of harm outcomes were explored. Results The review of current practice confirmed that data on harm outcomes is not being fully utilised, providing evidence of inappropriate and inconsistent practices. The scoping review revealed a broad range of methods for the analysis of both prespecified and emerging harms. The survey confirmed sub-optimal practices and while there was a moderate level of awareness of alternative approaches, use was limited. Guidance and training on more appropriate methods was unanimously supported. Recommendation were devised via consensus to encourage trialists to use visualisations for analysing and reporting harm outcomes. Of the evaluated methods for the analysis of emerging harms none were appropriate in trials ≤5000 participants with some utility in specific scenarios, recommendations for use are provided. Conclusion Clinical trial statisticians agree that there is a need to improve how we analyse and report harm outcomes in RCTs. Efforts to date have focused on prespecified harm outcomes, with little thought given to emerging harms. Several solutions for immediate adoption are proposed but there remains the need for an easy to implement, objective, signal detection approach. Guidelines for best analysis practice that are endorsed by key stakeholders would also enable a more coherent and consistent path for change.
Wikipedia en la Feria del Libro de Fráncfort. El editatón hispano-alemán de 2022
Creators: name: Zettl, Marie Lorena
name: Goebel, Swantje
Publisher: name: Estudios Culturales Hispánicos
Year: 2024

description: Este artículo presenta y analiza el editatón hispano-alemán que se organizó en el marco de la participación de España como país invitado de honor en la Feria del Libro de Fráncfort de 2022. Se centra en las particularidades del proyecto internacional y de la traducción en el contexto de Wikipedia. En el análisis también se incluyen los comentarios de los participantes para dar una visión global del proyecto.


This article aims to present and analyze the Spanish-German editathon that was organized within the context of Spain’s participation as Guest of Honor at the Frank­furt Book Fair 2022. The focus is on the particularities of the international project and translation in Wikipedia. The analysis also includes comments from participants in order to provide an overview of the project.


 
description: Estudios Culturales Hispánicos, Núm. 6 (2024)
Winter 1883/4
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1883

description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire August 2023 Minimalaufnahme nach Autopsie
description: Digitalisierung=Digitization=Numérisation August 2023 TIFF
description: Erschliessungsniveau Minimalniveau
Revista Ministerio Publico de Contas 2ªedição.
Creators: name: Ministério Publico de Contas do Estado de Minas Gerais
Publisher: name: Zenodo
Year: 2021

description: Apresentamos aos profissionais do controle externo e à comunidade acadêmica a 2ª edição da revista "Controle em Foco", o periódico semestral do Ministério Público de Contas do Estado de Minas Gerais (MPC/MG). Como na 1ª edição, a revista vem estruturada em três partes. A primeira, denominada "Artigos de Opinião", é composta de artigos escritos pelos procuradores do MPC/MG e traz temas atuais e situações práticas vivenciadas pelo controle externo, como estabilidade funcional, suspensão do prazo prescricional, registro dos atos de aposentadoria e publicidade institucional x propaganda governamental, além de temas importantes para a própria instituição do Ministério Público de Contas, como efetividade de sua atuação e o acordo de não persecução administrativa. Já a segunda seção, "Artigos de Jurisprudência Comentada", a revista conta com artigos que fazem uma análise técnica acerca de julgamentos relevantes, como o RMS n. 51841/CE, do Superior Tribunal de Justiça (STJ), acerca das requisições promovidas pelo Ministério Público de Contas, e o R.E. n. 1003433/ RJ, do Supremo Tribunal Federal (STF), a respeito da competência para execução de multas aplicadas pelos tribunais de contas. Por fim, a terceira seção, destinada aos "Artigos Científicos", traz importantes reflexões acerca do controle concomitante das prestações de contas das organizações sociais de saúde; da responsabilidade por danos ao erário nos tribunais de contas após a LINDB; da possibilidade de desconto compulsório em folha de pagamento para garantir efetividade às condenações dos tribunais de contas e, por fim, dos impactos nas políticas de emprego na União Europeia em decorrência da pandemia da COVID-19. Esperamos que essa 2ª edição possa servir de instrumento de promoção e disseminação do conhecimento, visando fomentar o debate de questões atuais e relevantes para o aperfeiçoamento institucional, bem como das atividades voltadas ao controle externo da administração pública. A todos, uma ótima leitura!
Modelling the evaporation of cryogenic liquids in storage tanks
Creators: name: Huerta Perez, Felipe
Publisher: name: Imperial College London
Year: 2021

description: Cryogenic liquids are substances with a normal boiling point below -150°C. Recently, the interest in cryogenic liquids has skyrocketed because of their role in the energy transition, particularly for LNG and liquid hydrogen. Cryogenic liquids are stored in highly insulated tanks, which are nevertheless subject to heat ingress from the surroundings. The heat ingress drives thermal stratification, natural convection, pressure build-up and evaporation. Managing the evaporated cryogen, denominated boil-off gas (BOG), pose techno-economic, safety and environmental challenges. To facilitate the design and operation of cryogenic storage tanks, new models for cryogenic liquids evaporation have been developed. For isobaric storage, a 1-D model has been developed. The model includes wall heating, heat conduction and advection in the vapour phase. The model shows that advection dominates vapour heat transfer. A 2-D CFD model has been developed to validate the assumptions of the 1-D model. The CFD model validates the 1-D model assumption of one-dimensional advective flow. Additionally, the CFD model shows that thermal stratification dampens natural convection in the vapour. Analytical solutions of the 1-D model valid for the pseudo-steady state have been developed. The analytical solutions constitute an easy-to-use tool for practitioners to improve BOG management. For non-isobaric storage, a 1-D model that considers wall heating, heat conduction and wall boiling has been developed. The 1-D model demonstrates that wall boiling is relevant even for low heat fluxes. The 1-D model predictions were in good agreement with experimental pressure and vapour temperature profiles. The assumptions of the 1-D model have been validated by developing a new single-phase CFD model. A multiphase model has been developed to investigate interfacial transport phenomena. It shows that interfacial momentum transfer slightly enhances liquid heat transfer, and that vapour heating dominates pressure build-up at the beginning of the storage period.
Walther L. Bernecker / Carlos Collado Seidel, eds. (2022). Spanien heute. Politik, Wirtschaft, Kultur. 6a. ed.
Creators: name: Pöppel, Hubert
Publisher: name: Estudios Culturales Hispánicos
Year: 2024

description: Reseña
description: Estudios Culturales Hispánicos, Núm. 6 (2024)
Singular Value and Frame Decomposition-based Reconstruction for Atmospheric Tomography
Creators: name: Weissinger, Lukas
name: Hubmer, Simon
name: Stadler, Bernadett
name: Ramlau, Ronny
Publisher: name: arXiv
Year: 2024
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: Atmospheric tomography, the problem of reconstructing atmospheric turbulence profiles from wavefront sensor measurements, is an integral part of many adaptive optics systems used for enhancing the image quality of ground-based telescopes. Singular-value and frame decompositions of the underlying atmospheric tomography operator can reveal useful analytical information on this inverse problem, as well as serve as the basis of efficient numerical reconstruction algorithms. In this paper, we extend existing singular value decompositions to more realistic Sobolev settings including weighted inner products, and derive an explicit representation of a frame-based (approximate) solution operator. These investigations form the basis of efficient numerical solution methods, which we analyze via numerical simulations for the challenging, real-world Adaptive Optics system of the Extremely Large Telescope using the entirely MATLAB-based simulation tool MOST.
description: 31 pages, 11 figures
Representaciones de la edición en euskera en Fráncfort 2022
Creators: name: Ibarluzea Santisteban, Miren
Publisher: name: Estudios Culturales Hispánicos
Year: 2024

description: Tras una descripción del campo editorial vasco, que engloba la edición en eus­kera, describiremos la participación y representación de los agentes vascos en la Feria del Libro de Fráncfort 2022, que se agrupan y presentan mediante asociaciones geográficas y lingüísticas diversas. Veremos que existen dobles implicaciones de algunos de los agentes y daremos cuenta de iniciativas creadas como contrapunto a la perspectiva pluricultural y lingüística ofrecida por parte de la programación oficial de la Feria del Libro de Fráncfort 2022.


Euskarazko argitalpenak ere biltzen dituen euskal edizioaren eremuaren deskribapena egin ondoren, Frankfurteko 2022ko Liburu Azokan euskal eragileek izanda­ko parte-hartzea eta ordezkaritza deskribatuko dugu. Ikusiko dugunez, askotariko eragile­tan taldekatzen dira euskal argitaletxeak, irizpide geografiko eta linguistikoen arabera. Hala, zenbait eragileren inplikazio bikoitzak azaleratuko ditugu. Halaber, 2022ko Frank­furteko Liburu Azokaren programazio ofizialak eskainitako kultura- eta hizkuntza-ikus­pegi anitzaren kontrapuntu gisa sortutako ekimenen berri ere emango dugu.


After a description of the Basque publishing field, which includes publishing in Basque Language, we will describe the participation and the representation of Basque agents at the Frankfurt Book Fair 2022. We will describe, as well, how the agents are grouped and presented by different geographical and linguistic associations and that some of them are dually involved. We will also pay attention to the existence of initiatives created as a counterpoint to the pluricultural and plurilinguistic perspective offered by part of the official programme.
description: Estudios Culturales Hispánicos, Núm. 6 (2024)
2HOT: An Improved Parallel Hashed Oct-Tree N-Body Algorithm for Cosmological Simulation
Creators: name: Warren, Michael S.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We report on improvements made over the past two decades to our adaptive treecode N-body method (HOT). A mathematical and computational approach to the cosmological N-body problem is described, with performance and scalability measured up to 256k ($2^{18}$) processors. We present error analysis and scientific application results from a series of more than ten 69 billion ($4096^3$) particle cosmological simulations, accounting for $4 \times 10^{20}$ floating point operations. These results include the first simulations using the new constraints on the standard model of cosmology from the Planck satellite. Our simulations set a new standard for accuracy and scientific throughput, while meeting or exceeding the computational efficiency of the latest generation of hybrid TreePM N-body methods.
description: 12 pages, 8 figures, 77 references; To appear in Proceedings of SC '13
Flächen 2. Grades in analytisch geometrischer Behandlungsweise, Vorlesung von Adolf Hurwitz.
Notizen, ausgearbeitet von Adolf Hurwitz
Creators: name: Hurwitz, Adolf
Publisher: name: [s.n.]
Year: 1883

description: Notizen zur Vorlesung, vorgetragen im Wintersemester 1883/84 an der Georg-August-Universität Göttingen.
Text mit Figuren.
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