cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Quasinormal modes of scalar field coupled to Einstein's tensor in the non-commutative geometry inspired black hole
Creators: name: Yan, Zening
name: Wu, Chen
name: Guo, Wenjun
Publisher: name: arXiv
Year: 2020
Subjects: subject: Nuclear Theory (nucl-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We investigate the quasinormal modes (QNMs) of the scalar field coupled to the Einstein's tensor in the non-commutative geometry inspired black hole spacetime. It is found that the lapse function of the non-commutative black hole metric can be represented by a Kummer's confluent hypergeometric function, which can effectively solve the problem that the numerical results of the QNMs are sensitive to the model parameters and make the QNMs values more reliable. We make a careful analysis of the scalar QNM frequencies by using several numerical methods, and find that the numerical results obtained by the new WKB method (the Padé approximants) and the Mashhoon method (P$\ddot{\text{o}}$schl-Teller potential method) are quite different from those obtained by the asymptotic iterative method (AIM) and time-domain integration method when the non-commutative parameter $θ$ and coupling parameter $η$ are large. The most obvious difference is that the numerical results obtained by the AIM and the time-domain integration method appear a critical value $η_c$ with an increase of $η$, which leads to the dynamical instability. After carefully analyzing the numeral results, we conclude that the numerical results obtained by the AIM and the time-domain integration method are closer to the theoretical values than those obtained by the WKB method and the Mashhoon method, when the $θ$ and $η$ are large. Moreover, through a numerical fitting, we obtain that the functional relationship between the threshold $η_c$ and the non-commutative parameter $θ$ satisfies $η_{c}=aθ^{b}+c$ for a fixed $l$ approximately. We find that the stability of dynamics can be ensured in the $η
description: 28 pages, 7 figures. Owing to the first author's nice insight, the Kummer's confluent hypergeometric function is first found as the representation of the lapse function of the non-commutative black hole metric
Der Aufbau einer „Entity Collection“ der Forschungsleistung der TU Dortmund
Creators: name: Becker, Hans-Georg
name: Höhner, Kathrin
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: Datenkuratierung
subject: Metadatenmanagement
subject: 020
subject: Metadaten
subject: Datenmanagement

description: Mit einer systematischen Kuratierung der lokalen Daten will die Universitätsbibliothek das Ziel erreichen, die Forschungsleistung der Technischen Universität Dortmund möglichst vollständig sichtbar und nachnutzbar zu machen. Um Data Curation effizient zu gestalten, verfolgt die Universitätsbibliothek Dortmund ein umfassendes Gesamtkonzept. So werden ein Metadaten-Managementsystem (MMS) und eine Datenplattform entwickelt, die auf die Nachnutzung möglichst vieler bereits existierender und verlinkbarer Identifikatoren zielen. Zudem bietet das Metadaten-Managementsystem die Möglichkeit, unterschiedlichste Datentypen mit verschiedenen Relationen zu erfassen. Es ist daher für das Monitoring der an der Technischen Universität Dortmund produzierten und nachzuweisenden Forschungsdaten besonders geeignet. Auch wird es eine Synchronisation mit dem Katalog plus der Universitätsbibliothek geben. Für die Wissenschaftlerinnen und Wissenschaftler wird es für die unterschiedlichen Anwendungsszenarien eine einzige Oberfläche als Einstieg geben. Hierüber können sie nicht nur Publikationen für die Hochschulbibliographie melden, Volltexte in das Repositorium hochladen oder Publikationslisten für Webseiten generieren, sondern auch finanzielle Unterstützung für Open Access-Publikationen beantragen.
Constraining the properties of spots on Pleiades very low mass stars
Creators: name: Scholz, Alexander
name: Eisloeffel, Jochen
name: Froebrich, Dirk
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present results of a multi-filter monitoring campaign for very low mass (VLM) stars in the Pleiades. Simultaneous to our I-band time series (Scholz & Eisloeffel 2004), which delivered photometric periods for nine VLM stars, we obtained light curves in the J- and H-band. One VLM star with M~0.15 Ms (BPL129) shows a period in all three wavelength bands. The amplitudes in I, J, and H are 0.035, 0.035, and 0.032 mag. These values are compared to simulations, in which we compute the photometric amplitude as a function of spot temperature and filling factor. The best agreement between observations and models is found for cool spots with a temperature contrast of 18-31% and a very low surface filling factor of 4-5%. We suggest that compared to more massive stars VLM objects may have either very few spots or a rather symmetric spot distribution. This difference might be explained with a change from a shell to a distributed dynamo in the VLM regime.
description: 9 pages, 5 figures, Astronomy & Astrophysics, in press
THE DIFFERENTIAL IMPACT OF CORRUPTION ON MICROENTERPRISES IN RUSSIA
Creators: name: Safavian, Mehnaz S.
name: Sheldon, Ian M.
name: Graham, Douglas H.
name: Gonzalez-Vega, Claudio
name: Safavian, Mehnaz S.
name: Sheldon, Ian M.
name: Graham, Douglas H.
name: Gonzalez-Vega, Claudio
Publisher: name: Unknown
Year: 2001
Subjects: Political Economy

description: Over the past decade, the repressive legal and regulatory environment in transition economies has received considerable attention in the literature. In Russia, this framework has resulted in an environment in which rules and regulations govern almost all aspects of economic activity. The elaborate system of regulations with which firms must comply, in combination with a lack of accountability for regulatory enforcers, has created a corrupt cadre of government officials who frequently engage in rent-seeking behavior while monitoring and enforcing firm compliance. The objective of this paper is to investigate the manner in which corruption affects micro and small enterprises in Russia. Empirical evidence suggests that micro and small enterprises vary substantially in reporting how problematic corruption is for their enterprise. A theoretical model explores why extortion from regulators may occur in a non-uniform manner across firms. The theoretical model postulates that government regulators customize the nature of their rent-seeking activities towards, similar to a price-discriminating monopolist facing hidden information. The model shows that production technologies, input choices, and other firm characteristics such as location play a role in determining the bribe price that a regulator will charge a firm, as well as the number of times he will return to collect it. Supportive evidence comes from survey data collected on Russian microenterprises. The model described above is tested using econometrics, and numerical simulations.
Nonlinear $k_{\perp}$-factorization: a new paradigm for an in-nucleus hard QCD
Creators: name: Nikolaev, N. N.
name: Schäfer, W.
name: Zakharov, B. G.
name: Zoller, V. R.
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We review the origin, and salient features, of the breaking of the conventional linear $k_{\perp}$-factorization for an in-nucleus hard pQCD processes. A realization of the nonlinear $k_{\perp}$-factorization which emerges instead is shown to depend on color properties of the underlying pQCD subprocesses. We discuss the emerging universality classes and extend nonlinear $k_{\perp}$-factorization to AGK unitarity rules for the excitation of the target nucleus.
description: 16 pages, 2 figures, to be published in Preceedings of Gribov-75: Memorial Workshop On Quarks, Hadrons, And Strong Interactions, 22-24 May 2005, Budapest, Hungary
Η εκπαίδευση και η κατάρτιση στο πλαίσιο της πολιτικής ασφάλειας της Ευρωπαϊκής Ένωσης: ο Οργανισμός για την Κατάρτιση στον Τομέα Επιβολής του Νόμου (CEPOL)
Creators: name: Θάνος, Ορέστης
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Ευρωπαϊκή Αστυνομική Ακαδημία
subject: Εκπαίδευση υπαλλήλων επιβολής του νόμου
subject: Ηλεκτρονική μάθηση
subject: Διαδικασία της Μπολόνια
subject: ΚΕΠΠΑ
subject: ΚΠΑΑ

description: Στο πολυσύνθετο σύγχρονο διεθνές σύστημα, ο ρόλος της άμυνας και της εσωτερικής ασφάλειας των κρατών αναβαθμίζεται συνεχώς. Η ανάπτυξη της τεχνολογίας των τηλεπικοινωνιών και των μεταφορών οδήγησαν στην ανάδυση νέων απειλών, αλλά και νέων μορφών αντιμετώπισής τους. Η Κοινή Εξωτερική Πολιτική και Πολιτική Ασφαλείας (ΚΕΠΠΑ) και η Κοινή Πολιτική Άμυνας Ασφάλειας (ΚΠΑΑ) της ΕΕ διαδραματίζει όλο και σημαντικότερο ρόλο για τα κράτη μέλη της, καθώς αυτά αδυνατούν να αντιμετωπίσουν μεμονωμένα τις τρέχουσες παγκόσμιες εξελίξεις. Η συνεργασία στον τομέα της εκπαίδευσης των υπαλλήλων επιβολής του νόμου τους είναι μονόδρομος, προκειμένου να δημιουργηθούν κοινά πρότυπα αστυνόμευσης τα οποία θα είναι πιο αποτελεσματικά και θα μπορούν να διασφαλίσουν την ειρηνική και ασφαλής διαβίωση των Ευρωπαίων πολιτών. Η παρούσα διπλωματική εργασία αναλύει ενδελεχώς τη λειτουργία του Οργανισμού της ΕΕ για την Κατάρτιση στον Τομέα της Επιβολής του Νόμου (CEPOL) ή Ευρωπαϊκή Αστυνομική Ακαδημία (ΕΑΑ) και συμπεραίνεται πως οι δραστηριότητές της συμβάλλουν στη δημιουργία μίας κοινής εκπαιδευτικής κουλτούρας των υπαλλήλων επιβολής του νόμου, καθώς επίσης και στη διαδικασία ολοκλήρωσης της ΚΠΑΑ της ΕΕ. Το υψηλό επίπεδο της παρεχόμενης εκπαίδευσης στο πλαίσιο της ΕΑΑ, η ανταλλαγή καλών πρακτικών, η προσπάθεια προώθησης της Διαδικασίας της Μπολόνια στην αστυνομική εκπαίδευση, και η παροχή ενός χώρου ανάπτυξης της αστυνομικής έρευνας, επιστήμης και του εποικοδομητικού επιστημονικού διαλόγου, είναι καθοριστικής σημασίας για την άνοδο του επαγγελματισμού των υπαλλήλων επιβολής του νόμου, με αποτέλεσμα την αύξηση του αισθήματος ασφαλείας των Ευρωπαίων πολιτών, πράγμα που αντικατοπτρίζεται στην πολιτική σταθερότητα των ευρωπαϊκών κοινωνιών.
Διαχείριση χωρο-κειμενικών δεδομένων μεγάλης κλίμακας
Creators: name: Ψαρρός, Αντώνης
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2021
Subjects: subject: Apache Spark
subject: Spatio-textual join
subject: Spatial join
subject: Web-based platform

description: Κατά την εκπόνηση της παρούσας Διπλωματικής εργασίας πραγματεύθηκε το πρόβλημα της σύζευξης μεγάλου όγκου χωροκειμενικών δεδομένων. Δεδομένα τα οποία αποτελούνται από εγγραφές όπου η κάθε μία περιέχει (lon,lat,text) όπου lon, lat είναι οι συντεταγμένες και text είναι το κείμενο κάθε εγγραφής, κάθε εγγραφή αποτελεί ένα αντικείμενο x. Το κριτήριο για την ομοιότητα δύο αντικείμενων x,v είναι ο έλεγχος της απόστασης στο χώρο των x,v το οποίο υπολογίζεται με τον τύπο Haversine Distance. Για την εύρεση της ομοιότητας του κειμένου των δύο αντικειμένων x,v χρησιμοποιείται το τύπος Jaccard Similarity. Για το παραπάνω πρόβλημα δημιουργήθηκε ένας αλγόριθμος που το υλοποιεί και έγινε εφαρμογή αυτού του αλγορίθμου σε κατανεμημένο περιβάλλον από υπολογιστές με χρήση του εργαλείου Apache Spark, όπου χρησιμοποίει τις δυνατότητες επεξεργασίας δεδομένων του επεξεργαστή κάθε υπολογιστή. Επίσης, έγινε μια επιπλέον υλοποίηση του αλγορίθμου με σκοπό να εκμεταλλεύεται τις δυνατότητες επεξεργασίες της κάρτας γραφικών κάτι που επιτεύχθηκε χρησιμοποιώντας εργαλεία της Nvidia. Τέλος, με για την εκτέλεση αλγορίθμων χωροκειμενικής σύζευξης σε Apache Spark δημιουργήθηκε διαδικτυακή πλατφόρμα με σκοπό να έχει τη δυνατότητα ένας χρήστης να ανεβάζει έναν αλγόριθμο που απαντά σε αυτό το πρόβλημα, να τον εκτελεί και να κάνει προβολή των αποτελεσμάτων σε χάρτη. Επιπλέον, ο χρήστης μπορεί να κάνει προβολή των dataset που δέχεται σαν είσοδο ο κάθε αλγόριθμος σε χάρτη.
A FACTOR ANALYSIS OF SUPERMARKET MANAGEMENT PRACTICES
Creators: name: King, Robert P.
name: Jacobson, Elaine M.
name: King, Robert P.
name: Jacobson, Elaine M.
Publisher: name: Unknown
Year: 2001
Subjects: Agribusiness

description: Empirically based management practice indices are constructed using results from factor analysis of data from 344 stores in the 2000 Supermarket Panel. These indices are compared to six management indices based on expert opinion. The empirical indices group variables differently and provide a more compact summary of supermarket management practices.
A user journey : development of drone-based medication delivery : meeting developers and co-developers’ expectations
Creators: name: Lehmann, Anne
name: Kalter, Ivonne
name: Jahn, Patrick
name: Fink, Franziska
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2025
Subjects: subject: 610

description: This study builds on initial ADApp research that identified the factors that influence the intention to use a pharmacy drone app for urgent medication delivery. While previous studies and theories have predominantly focused on user acceptance alone, the present qualitative study introduced a holistic model that integrates user acceptance theories as well as user-centered design principles and technology features. It focused on the user journey to derive core statements from the development of a drone-based application using a qualitative theory synthesis approach (study 1), and explored the perceived participatory collaboration between developers (software and drone developers) and co-developers (core group participants) using final tandem discussions and a qualitative content analysis method (study 2). Study 1 resulted in the identification of eight categories that serve as technical working goals for future participatory technology development. Study 2 identified five critical factors that provide insight into the unique challenges and goals of collaborative development. Both studies contribute to a better understanding of the essential factors that lead to successful participatory processes between developers and co-developers aimed at increasing usability and intention to use. Based on these findings, an integrated model is presented to support participatory design strategies in healthcare technology development.
Order and disorder in columnar joints
Creators: name: Goehring, Lucas
name: Morris, Stephen W.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: Columnar joints are three-dimensional fracture networks that form in cooling basalt and several other media. The network organizes itself into ordered, mostly hexagonal columns. The same pattern can be observed on a smaller scale in desiccating starch. We show how surface boundary conditions in the desiccation of starch affect the formation of columnar joints. Under constant drying power conditions, we find a power law dependence of columnar cross-sectional area with depth, while under constant drying rate conditions this coarsening is eventually halted. Discontinuous transitions in pattern scale can be observed under constant external conditions, which may prompt a reinterpretation of similar transitions found in basalt. Starch patterns are statistically similar to those found in basalt, suggesting that mature columnar jointing patterns contain inherent residual disorder, but are statistically scale invariant.
description: 7 pages, 5 figures, will appear in Europhys. Lett. This arXiv version has smaller, somewhat blurrier figures. For a sharper version, see http://www.physics.utoronto.ca/nonlinear
Structured Index Coding Problem and Multi-access Coded Caching
Creators: name: Reddy, Kota Srinivas
name: Karamchandani, Nikhil
Publisher: name: arXiv
Year: 2020
Subjects: subject: Information Theory (cs.IT)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Combinatorics (math.CO)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Index coding and coded caching are two active research topics in information theory with strong ties to each other. Motivated by the multi-access coded caching problem, we study a new class of structured index coding problems (ICPs) which are formed by the union of several symmetric ICPs. We derive upper and lower bounds on the optimal server transmission rate for this class of ICPs and demonstrate that they differ by at most a factor of two. Finally, we apply these results to the multi-access coded caching problem to derive better bounds than the state of the art.
description: 44 pages, single column, ITW and JSAIT
How people in eight european countries felt about the safety, effectiveness, and necessity of COVID-19 vaccination : a cross-sectional survey
Creators: name: Coteur, Kristien
name: Zafirovska, Marija
name: Zafirovski, Aleksandar
name: Danilenko, Jelena
name: Lingner, Heidrun
name: Bauch, Felix
name: Brütting, Christine
name: Buono, Nicola
name: Lazic, Vanja
name: Ramasaco, Liljana
name: Silina, Vija
name: Fühner, Lara-Marie
name: Harris, Michael
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2025
Subjects: subject: 610

description: Background/objectives: Attitudes towards COVID-19 vaccination vary globally, influenced by political and cultural factors. This research aimed to assess the views of people without a healthcare qualification in Europe on COVID-19 vaccination safety, effectiveness, and necessity as well as how well informed they felt. The secondary outcomes focused on how respondents’ views were affected by demographic and context factors and included a comparison by country of the level of feeling well informed. Methods: A mixed-method cross-sectional online survey in eight European countries, using convenience sampling. Results: A total of 1008 adults completed the survey, 60% of whom were female. While only 44.1% considered the vaccines safe, 43.5% effective, and 44.9% necessary, 80.0% had been vaccinated. Four in ten adults strongly agreed that they were well informed, while over a quarter did not answer the question. Younger respondents, well-informed individuals, and German respondents were more inclined to perceive COVID-19 vaccination as both effective and necessary. Conclusions: Motivations for vaccination included perceived health and social benefits, while concerns included a preference for “natural immunity”, the rapid development of the vaccine, and potential unknown long-term effects. A correlation existed between respondents feeling well informed about the different COVID-19 vaccines in their country and the likelihood of having been vaccinated.
COMMODITY R&D, PATENTING, AND PROMOTION
Creators: name: Richards, Timothy J.
name: Padilla, Luis
name: Richards, Timothy J.
name: Padilla, Luis
Publisher: name: Unknown
Year: 2001
Subjects: Research and Development/Tech Change/Emerging Technologies

description: There is considerable evidence of high returns to public investments in agricultural R&D, but because intellectual property in agriculture is considered a public good, little R&D investment by growers themselves. This study investigates the potential for growers to increase commodity sales through product research, development, patenting and promotion in a dynamic commodity-market model. Theoretical hypotheses derived from the solution to this model are tested in an empirical example from Washington apples. Estimation results show that, despite significant spillovers to research and promotion expenditure, growers can improve the effectiveness of generic commodity promotion by funding R&D programs as well.
Exclusive dimuon production in ultraperipheral Pb+Pb collisions at $\sqrt{s_{\mathrm{NN}}} = 5.02$ TeV with ATLAS
Creators: name: ATLAS Collaboration
Publisher: name: arXiv
Year: 2020
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Exclusive dimuon production in ultraperipheral collisions (UPC), resulting from photon-photon interactions in the strong electromagnetic fields of colliding high-energy lead nuclei, $\mathrm{PbPb}(γγ) \rightarrow μ^+μ^- (\mathrm{Pb}^{(\star)}\mathrm{Pb}^{(\star)} )$, is studied using $\mathcal{L}_{\mathrm{int}} = 0.48$ nb$^{-1}$ of $\sqrt{s_\mathrm{NN}}=5.02$ TeV lead-lead collision data at the LHC with the ATLAS detector. Dimuon pairs are measured in the fiducial region $p_{\mathrm{T}μ} > 4$ GeV, $|η_μ| < 2.4$, invariant mass $m_{μμ} > 10$ GeV, and $p_{\mathrm{T,μμ}} < 2$ GeV. The primary background from single-dissociative processes is extracted from the data using a template fitting technique. Differential cross sections are presented as a function of $m_{μμ}$, absolute pair rapidity ($|y_{μμ}|$), scattering angle in the dimuon rest frame ($|\cos \vartheta^{\star}_{μμ}|$) and the colliding photon energies. The total cross section of the UPC $γγ\rightarrow μ^{+}μ^{-}$ process in the fiducial volume is measured to be $σ_{\mathrm{fid}}^{μμ} = 34.1 \! \pm \! 0.3 \mathrm{(stat.)} \! \pm \! 0.7 \mathrm{(syst.)}$ $μ\mathrm{b}$. Generally good agreement is found with calculations from STARlight, which incorporate the leading-order Breit-Wheeler process with no final-state effects, albeit differences between the measurements and theoretical expectations are observed. In particular, the measured cross sections at larger $|y_{μμ}|$ are found to be about 10-20% larger in data than in the calculations, suggesting the presence of larger fluxes of photons in the initial state. Modification of the dimuon cross sections in the presence of forward and/or backward neutron production is also studied and is found to be associated with a harder incoming photon spectrum, consistent with expectations.
description: 50 pages in total, author list starting page 34, 12 figures, published by Phys. Rev. C. All figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2016-02/
Transformer-based End-to-End Speech Recognition with Local Dense Synthesizer Attention
Creators: name: Xu, Menglong
name: Li, Shengqiang
name: Zhang, Xiao-Lei
Publisher: name: arXiv
Year: 2020
Subjects: subject: Sound (cs.SD)
subject: Computation and Language (cs.CL)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 68T10

description: Recently, several studies reported that dot-product selfattention (SA) may not be indispensable to the state-of-theart Transformer models. Motivated by the fact that dense synthesizer attention (DSA), which dispenses with dot products and pairwise interactions, achieved competitive results in many language processing tasks, in this paper, we first propose a DSA-based speech recognition, as an alternative to SA. To reduce the computational complexity and improve the performance, we further propose local DSA (LDSA) to restrict the attention scope of DSA to a local range around the current central frame for speech recognition. Finally, we combine LDSA with SA to extract the local and global information simultaneously. Experimental results on the Ai-shell1 Mandarine speech recognition corpus show that the proposed LDSA-Transformer achieves a character error rate (CER) of 6.49%, which is slightly better than that of the SA-Transformer. Meanwhile, the LDSA-Transformer requires less computation than the SATransformer. The proposed combination method not only achieves a CER of 6.18%, which significantly outperforms the SA-Transformer, but also has roughly the same number of parameters and computational complexity as the latter. The implementation of the multi-head LDSA is available at https://github.com/mlxu995/multihead-LDSA.
description: 5 pages, 3 figures
TESTS FOR THE ROLE OF RISK AVERSION ON INPUT USE
Creators: name: Roosen, Jutta
name: Hennessy, David A.
name: Roosen, Jutta
name: Hennessy, David A.
Publisher: name: Unknown
Year: 2001
Subjects: subject: Farm Management
subject: Risk and Uncertainty
subject: dominance tests
subject: incomplete risk markets
subject: ollution
subject: stochastic technology

description: Agricultural inputs can create negative externalities. For risk averting agents, risk will alter production decisions while the existence of institutions to insure against adverse states of nature will likely restore decisions toward levels under risk neutrality. In this paper, conditions are identified on a stochastic technology to test that risk averters choose smaller input levels than risk neutral agents, and that an increase in risk aversion reduces input use. A robust statistical method (Klecan, McFadden, and McFadden) to test for dominance is adapted to stochastic production relations. It is found that the first hypothesis is likely true for nitrogen application on Iowa corn. Weaker evidence is found in favor of the second hypothesis.
title: A novel medium size lactam ring analoges as antibacterial agents
title: synthesis, biological evaluation and molecular docking studies
titleType: AlternativeTitle
Creators: name: Putcha A. N. V., Harita
name: Putcha, Seshi Kumar
name: Guduru, Shiva Krishna Reddy
name: Ravula, Parameshwar
name: Sharath Chandra, J N Narendra
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: medium size ring
subject: synthesis
subject: coupling reaction
subject: lactam
subject: bacillus subtilis
subject: anti-bacterial
subject: docking
subject: 610

description: A novel series of medium size (S)-3-alkyl-3,4,6,7-tetrahydro-1H-benzo[e][1,4]diazonine-2,5-dione (6a-f) analogues were synthesized from (E)-3-(2-nitrophenyl)acrylicacid (2) reacting with various amino acid esters using Di-isopropyl Carbodiimide as a coupling agent. The final cyclization is carried out by using reagent 1-Ethyl-3(3- dimethylaminopropyl) Carbodiimide Hydrochloride. The synthesized compounds have been supported by Mass, 1H-NMR and 13C-NMR. Further antibacterial studies were conducted, where some molecules are noticed with potent activity, especially molecule 6d shown highest activity which was also supported by molecular docking studies. All final molecules were docked with enzyme peptide deformylase to determine the probable binding conformation.
description: EXCLI Journal;Vol. 16 2017
Cancer chemoprevention by oleaster (Elaeagnus angustifoli L.) fruit extract in a model of hepatocellular carcinoma induced by diethylnitrosamine in rats
Creators: name: Amereh, Zahra
name: Hatami, Nasrin
name: Shirazi, Farshad H.
name: Gholami, Saman
name: Hosseini, Seyed Hojjat
name: Noubarani, Maryam
name: Kamalinejad, Mohammad
name: Andalib, Sina
name: Keyhanfar, Fariborz
name: Eskandari, Mohammad Reza
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: E. angustifolia
subject: cancer prevention
subject: carcinogenesis
subject: liver cancer
subject: Russian olive
subject: wild olive
subject: 610

description: Hepatocellular carcinoma (HCC) is a frequent and fatal human cancer with poor diagnosis that accounts for over half a million deaths each year worldwide. Elaeagnus angustifolia L. known as oleaster has a wide range of pharmacological activities. This study aimed to investigate the chemopreventive effect of aqueous extract of E. angustifolia fruit (AEA) against diethylnitrosamine (DEN)-induced HCC in rats. HCC was induced in rats by a single injection of DEN (200 mg/kg) as an initiator. After two weeks, rats were orally administered 2-acetylaminofluorene or 2-AAF (30 mg/kg) as a promoter for two weeks. Oleaster-treated rats were orally pretreated with the increasing doses of AEA two weeks prior to DEN injection that continued until the end of the experiment. In the current study, a significant decrease in serum biomarkers of liver damage and cancer, including alfa-fetoprotein (AFP), gamma glutamyl transpeptidase (GGT), alanine transaminase (ALT), and aspartate transaminase (AST) was observed in AEA-treated rats when compared to HCC rats. Furthermore, the oleaster extract exhibited in vivo antioxidant activity by elevating reduced glutathione (GSH) contents as well as preventing lipid peroxidation in the liver tissues of DEN-treated rats. The relative weight of liver, a prognostic marker of HCC, was also reduced in oleaster-treated rats. To conclude, our results clearly demonstrated that oleaster fruit possesses a significant chemopreventive effect against primary liver cancer induced by DEN in rats. It can be suggested that the preventive activity of oleaster against hepatocarcinogenesis may be mediated through the antioxidant, anti-inflammation, and antimutagenic effects of the fruit.
description: EXCLI Journal;Vol. 16 2017
RNA-Sequenzierung zur Analyse Epstein-Barr-Virus-codierter microRNAs
Creators: name: Hohmann, Tim
name: Jasinski-Bergner, Simon
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2025
Subjects: subject: 610

description: The RNA species of microRNAs represents an important component of post-transcriptional gene regulation. Herpes viruses, including the Epstein-Barr virus, encode their own microRNA genes, which play a relevant role in crucial cellular processes, including immune evasion, but also in the malignant transformation of host cells. Modern transcriptome analyses, including RNA sequencing, contribute significantly to the identification of these direct and indirect molecular regulatory relationships.
Closed Quasi-Fuchsian Surfaces In Hyperbolic Knot Complements
Creators: name: Masters, Joseph D.
name: Zhang, Xingru
Publisher: name: arXiv
Year: 2006
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: We show that every hyperbolic knot complement contains a closed quasi-Fuchsian surface.
description: 69 pages, 27 figures. Made small changes suggested by referee
COMPARISON OF CONVENTIONAL AND TRANSGENIC TECHNOLOGIES UNDER ALTERNATIVE CULTURAL PRACTICES FOR COTTON IN GEORGIA
Creators: name: Ward, Clayton
name: White, Fred C.
name: Isengildina, Olga
name: Ward, Clayton
name: White, Fred C.
name: Isengildina, Olga
Publisher: name: Unknown
Year: 2001
Subjects: Crop Production/Industries
Research and Development/Tech Change/Emerging Technologies

description: This study was conducted to determine allocative efficiency and cost effectiveness of growing conventional and transgenic cotton varieties under alternative cultural practices in South Georgia. A data envelopment model was used to compare costs and returns associated with various combinations of tillage and technology. The results suggest that combination of genetically modified cotton varieties and strip till cultivation practices yields a more efficient use of inputs relative to the level of output.
Δημοσιονομική αβεβαιότητα: πηγές και επιπτώσεις
Creators: name: Παππάς, Χρήστος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Δημοσιονομική αβεβαιότητα
subject: Αβεβαιότητα - Ανεργία
subject: Αβεβαιότητα - ΑΕΠ

description: Η παρούσα διατριβή εξετάζει την ενδεχόμενη επιρροή του δείκτη δημοσιονομικής αβεβαιότητας και των υποδεικτών του (δείκτης αβεβαιότητας χρέους και δείκτης αβεβαιότητας φορολογικής πολιτικής) από μεταβλητές που αφορούν την οικονομία αλλά και το αντίστροφο. Οι συγκεκριμένοι δείκτες αβεβαιότητας εκφράζονται ποσοτικά με τους δείκτες EPUF (δείκτης δημοσιονομικής αβεβαιότητας) EPUD (δείκτης αβεβαιότητας χρέους) και EPUT (δείκτης αβεβαιότητας φορολογικής πολιτικής). Για να βρεθεί η όποια επιρροή στην οικονομία ή από την οικονομία χρησιμοποιήθηκαν κάποιες βασικές μακροοικονομικές και χρηματοοικονομικές μεταβλητές. Αυτές είναι η ποσοστιαία μεταβολή του ΑΕΠ, η μεταβολή των αποδόσεων των δεκαετών ομολόγων, η μεταβολή της ανεργίας, η ποσοστιαία μεταβολή του δείκτη βιομηχανικής παραγωγής, η ποσοστιαία μεταβολή του δείκτη οικονομικού κλίματος και η ποσοστιαία μεταβολή του Γενικού Δείκτη Αθηνών. Εξετάσθηκαν ξεχωριστά τρεις περίοδοι: από τον Ιανουάριο του 2000 ως τον Ιούλιο του 2019, από τον Ιανουάριο του 2000 ως τον Σεπτέμβριο του 2009 (πριν εκδηλωθεί η κρίση στην Ελλάδα) και από τον Οκτώβριο του 2009 ως τον Ιούλιο του 2019 (μετά την εκδήλωση της κρίσης). Ειδικότερα, οι δείκτες αβεβαιότητας που χρησιμοποιήθηκαν δεν δείχνουν να επηρεάζουν την οικονομία σε τέτοιο βαθμό ώστε να εξαχθεί κάποιο σημαντικό συμπέρασμα. Σε πολυπαραγοντικό επίπεδο η εξέταση του επηρεασμού κάθε μίας μακροοικονομικής και χρηματοοικονομικής μεταβλητής από καθέναν δείκτη αβεβαιότητας, συμπληρωματικά με άλλες χρηματοοικονομικές και μακροοικονομικές μεταβλητές, δεν οδήγησε σε κάποιο συμπέρασμα γι’ αυτό και δεν παρουσιάζονται στην μελέτη. Μοναδική επιρροή βρέθηκε όταν απομονωμένα εξετάσθηκε η επιρροή του δείκτη δημοσιονομικής αβεβαιότητας και του δείκτη αβεβαιότητας του χρέους με την ανεργία η οποία ήταν θετική (σε μονοπαραγοντικές παλινδρομήσεις). Ακόμη, παρατηρήθηκε αρνητική επιρροή του δείκτη αβεβαιότητας για το χρέος στο ΑΕΠ. Από την άλλη, η εξέταση του επηρεασμού των δεικτών αβεβαιότητας από τις μεταβλητές της οικονομίας είχε πιο ενδιαφέροντα αποτελέσματα. Σε μονοπαραγοντικό επίπεδο οι ποσοστιαίες μεταβολές του δείκτη οικονομικού κλίματος και η ποσοστιαία μεταβολή του ΑΕΠ έχουν αρνητική επιρροή στον δείκτη αβεβαιότητας χρέους και στον δείκτη δημοσιονομικής αβεβαιότητας ενώ η ανεργία δείχνει να επηρεάζει θετικά τους ίδιους δείκτες για το σύνολο του δείγματος. Σε πολυπαραγοντικό επίπεδο, για να δοθεί και πληρέστερη εικόνα στην ανάλυση, σε παλινδρομήσεις όπου εξετάζεται η επιρροή των δεικτών αβεβαιότητας από τις υπόλοιπες μεταβλητές της οικονομίας, βρέθηκε ότι υπάρχει σημαντικός επηρεασμός των δεικτών αβεβαιότητας από τις υστερήσεις τους. Επιβεβαιώθηκαν σε κάποιες παλινδρομήσεις τα συμπεράσματα των μονοπαραγοντικών παλινδρομήσεων, ενώ αναδείχθηκε η αρνητική επιρροή της ποσοστιαίας μεταβολής του Γενικού Δείκτη Αθηνών με τον δείκτη αβεβαιότητας για το χρέος και την φορολογική πολιτική για την περίοδο πριν την έναρξη της κρίσης.
Charging in the vortex lattice of type-II superconductors
Creators: name: Ohuchi, Marie
name: Ueki, Hikaru
name: Kita, Takafumi
Publisher: name: arXiv
Year: 2020
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study the magnetic-field dependence of the vortex-core charge in the Abrikosov lattice of an $s$-wave superconductor based on the augmented quasiclassical equations, where we incorporate the pair-potential gradient (PPG) terms characteristic of charging in superconductors besides the well-known Lorentz force. Our numerical results at $T=0.2 T_{\rm c}$ and $0.5 T_{\rm c}$ reveal that periodic charge redistribution is superimposed on the magnetic flux-line lattice with different spatial patterns at different fields. The PPG terms are dominant at weak fields over the Lorentz force for accumulating charge in the vortex cores, whereas the Lorentz force prevails at higher fields to give rise to a peak structure in the core charge around $H\sim \frac{1}{2}H_{{\rm c}2}$. We estimate the peak value of the core charge at $T=0.2 T_{\rm c}$ using parameters appropriate for cuprates to obtain a large value of $Q \sim 10^{-2} |e|$ in the core region of radius $0.2 ξ_0$ in the $ab$ plane and length $1 \ {\rm nm}$ along the $c$ axis.
description: 8 pages, 4 figures
Inclusive Pion Double Charge Exchange in 4He at Intermediate Energies
Creators: name: Kinney, E. R.
name: Matthews, J. L.
name: Gram, P. A. M.
name: MacArthur, D. W.
name: Piasetzky, E.
name: Rebka,, G. A.
name: Roberts, D. A.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: A systematic experimental study of inclusive pion double charge exchange in 4He has been undertaken. The reaction 4He(pi+,pi-)4p was observed at incident energies 120, 150, 180, 240 and 270 MeV; the 4He(pi-,pi+)4n reaction was observed at incident energies 180 and 240 MeV. At each incident energy, the doubly differential cross section was measured at three to five outgoing pion laboratory angles between 25 deg and 130 deg. At each angle, cross sections were measured over the range of outgoing pion energies from 10 MeV up to the kinematic limit for the reaction in which the final state consists of the oppositely charged pion plus four free nucleons. The spectra of outgoing pions are strikingly different from those observed for the inclusive double charge exchange reaction in heavier nuclei, but resemble those observed in the (pi-,pi+) reaction in 3He. The forward-angle spectra in the 3He and 4He reactions exhibit a prominent peak at high outgoing pion energies. Interpretation of the peaks in 3He (4He) as a three- (four-)nucleon resonance is ruled out by kinematic analysis. The results of a calculation, wherein the double charge exchange reaction is assumed to proceed as two sequential single charge exchange interactions, suggest that the high-energy peak is naturally explained by this double scattering mechanism. Non-static treatment of the pi-N interactions and the inclusion of nuclear binding effects appear to be important in reproducing the shape of the energy spectra at forward angles.
description: 59 pages, 22 figures, 2 tables
Effects of platelet rich plasma and chondrocyte co-culture on MSC chondrogenesis, hypertrophy and pathological responses
Creators: name: Ramezanifard, Rouhallah
name: Kabiri, Mahboubeh
name: Hanaee Ahvaz, Hana
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: Mesenchymal stem cell
subject: AC:MSC co-culture
subject: PRP
subject: hypertrophy
subject: angiogenesis
subject: inflammation
subject: 610

description: Regarding the inadequate healing capability of cartilage tissue, cell-based therapy is making the future of cartilage repair and regeneration. Mesenchymal stem cells (MSC) have shown great promise in cartilage regeneration. However, a yet-unresolved issue is the emergence of hypertrophic and pathologic markers during in vitro MSC chondrogenesis. Articular chondrocytes (AC) can suppress the undesired hypertrophy when co-cultured with MSC. On the other hand, platelet rich plasma (PRP), is considered potentially effective for cartilage repair and in-vitro chondrogenesis. We thus aimed to harness chondro-promotive effects of PRP and hypertrophic-suppressive effects of AC:MSC co-culture to achieve a more functional cartilage neo-tissue. We used PRP or conventional-differentiation chondrogenic media (ConvDiff) in MSC mono-cultures and AC:MSC co-cultures. We assessed gene expression of chondrogenic and hypertrophic markers using real-time RT-PCR and immunostaining. Alkaline-phosphatase activity (ALP) and calcium content of the pellets were quantified. We also measured VEGF and TNF-α secretion via ELISA. We showed PRP had higher chondrogenic potential (in mRNA and protein level) and hypertrophic-suppressive effects than Conv-Diff (mRNA level). Co-culturing reduced ALP while PRP increased calcium deposition. In all four groups, TNF-α was down-regulated compared to MSC controls, with co-cultures receiving ConvDiff media secreting the least. Meanwhile, the only group with increased VEGF secretion was PRP-mono-cultures. We observed synergistic effects for PRP and AC:MSC co-culture in enhancing chondrogenesis. Inclusion of AC reduced hypertrophic markers and angiogenic potential in PRP groups. We thus propose that combination of PRP and co-culture would favor chondrogenesis while alleviate but not totally eradicate undesired hypertrophic and pathologic responses.
description: EXCLI Journal;Vol. 16 2017
Ανάλυση ιατρικών δεδομένων
Creators: name: Αγγελίδης, Χρήστος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2021
Subjects: subject: Μηχανική μάθηση
subject: Ανάλυση δεδομένων
subject: Feature selection
subject: Ανάλυση επιβίωσης
subject: Causal analysis
subject: Αλγόριθμοι
subject: Random forest
subject: Decision tree
subject: KNN
subject: Survival analysis
subject: OLS
subject: Matching
subject: Weighting
subject: Ιατρικά δεδομένα

description: Η παρούσα εργασία ασχολείται με την μελέτη και εξαγωγή συμπερασμάτων από δεδομένα νεφροπαθών ασθενών. Χρησιμοποιώντας Περιγραφική Στατιστική διερευνώνται πτυχές της ασθένειας, όπως ο συχνότερος τρόπος θανάτου των ασθενών, τα φάρμακα που συνταγογραφούνται, σε ποιες ηλικίες υπάρχει μεγαλύτερη θνησιμότητα κ.α. Χρησιμοποιούνται τεχνικές μηχανικής μάθησης ώστε να προβλεφθεί ο χρόνος ζωής των ασθενών, η αιτία θανάτου, καθώς και η οικονομική επιβάρυνση που προκαλεί η συγκεκριμένη ασθένεια στους ασθενείς, χρησιμοποιώντας χαρακτηριστικά που εξήχθησαν μέσω τεχνικών επιλογής χαρακτηριστικών (Feature Selection). Γίνεται ανάλυση θνησιμότητας ώστε να διαπιστωθεί ο χρόνος ζωής των ασθενών ανάλογα με το στάδιο που βρίσκονται, είτε σε αιμοκάθαρση είτε σε μεταμόσχευση. Τέλος χρησιμοποιώντας Causal Analysis διερευνήθηκε αν το φάρμακο ‘Trombyl’, ανάλογα με την δοσολογία του επιμηκύνει τη διάρκεια ζωής των ασθενών.
Inflationary solutions in the simplest gravity model with conformal symmetry
Creators: name: Alexeyev, S.
name: Krichevskiy, D.
Publisher: name: arXiv
Year: 2020
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We discuss a model of gravity with conformal symmetry appearing in the simplest extension of General Relativity with the Poincaré algebra terms. The nonlinear realization of symmetry causes the existence of five scalar fields. Therefore it looks desirable to use them for driving the inflation at the earliest stages of the Universe evolution. It is shown that the evolution of the scale factor doesn't imply accelerated expansion so that there are no inflationary solutions in this model. To drive inflation a more complicated model induced by extension of the Poincare algebra is required.
Troxerutin protects hippocampal neurons against amyloid beta-induced oxidative stress and apoptosis
Creators: name: Farajdokht, Fereshteh
name: Amani, Mohammad
name: Mirzaei Bavil, Fariba
name: Alihemmati, Alireza
name: Mohaddes, Gisou
name: Babri, Shirin
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: Alzheimer’s disease
subject: amyloid beta
subject: acetylcholinesterase
subject: oxidative stress
subject: 610

description: Alzheimer’s disease (AD) is an age-related neurodegenerative disease linked with increased production and/or deposition of amyloid-beta (Aβ) in the brain. The aim of the present study was to investigate the possible neuroprotective effect of troxerutin on an animal model of Alzheimer's disease. Alzheimer model was induced by a single dose intracerebroventricular (ICV) injection of Aβ 1–42 (5 nmol/5 μl). Thereafter, troxerutin (300 mg/kg) was gavaged for 14 days. The hippocampal malondialdehyde (MDA) levels and enzymatic activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), and acetylcholinesterase (AChE) were measured using enzymelinked immunosorbent assay (ELISA) method. In addition, the number of apoptotic cells in the dentate gyrus (DG) was assessed by TUNEL kit. The results showed that ICV microinjection of Aβ 1-42 increased MDA levels, reduced SOD and GPx, and increased AChE activities in the hippocampus. Chronic administration of troxerutin significantly attenuated MDA levels and AChE activity and increased SOD and GPx activities in the hippocampus. Moreover, the number of apoptotic cells was decreased by troxerutin treatment. Taken together, our study demonstrated that troxerutin could increase the resistance of hippocampal neurons against apoptosis, at least in part, by diminishing the activity of AChE and oxidative stress. Therefore, troxerutin may have beneficial effects in the management of Alzheimer's disease.
description: EXCLI Journal;Vol. 16 2017
Color Superconductivity and Radius of Quark Star in Extended NJL Model by Using the Dimensional Regularization
Creators: name: Fujihara, T.
name: Inagaki, T.
name: Kimura, D.
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A radius of a dense star on the color superconducting phase is investigated in an extended NJL type model with two flavors of quarks. Since the model is non-renormalizable, the results depend on the regularization procedure. Here we apply the dimensional regularization and evaluate the radius of a dense star. Evaluating the TOV equation, we show the relationship between mass and radius of the dense star in the dimensional regularization.
description: 4 pages.To appear in the proceedings of 7th Workshop on Quantum Field Theory Under the Influence of External Conditions (QFEXT 05), Barcelona, Catalonia, Spain, 5-9 Sep 2005. References are add
Elevated antibiotic resistance of Sudanese urinary tract infection bacteria
Creators: name: Saeed, Amir
name: Hamid, Shadia A.
name: Bayoumi, Magdi
name: Shanan, Salah
name: Alouffi, Sultan
name: Alharbi, Samir A.
name: Alshammari, Fawaz D.
name: Abd, Hadi
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: urinary tract infections
subject: bacteria
subject: antibiotic resistance
subject: 610

description: This study determined the prevalence of urinary tract infections in the Sudanese state of Khartoum and antimicrobial susceptibility pattern of isolated bacterial species. 200 adult patient urine specimens were collected and cultivated to identify the growing bacteria and their susceptibility to antibiotics. 35 % of specimens had significant bacterial growth. The most frequent isolates in this study were E. coli, E. faecalis and S. aureus. Most of the isolates were resistant to many antibiotics; Gram-negative and Gram-positive isolates were resistant to 67 % and 44 % of the examined antibiotics, respectively. E. coli was the most frequent bacterium in the studied samples and it was highly resistant to first-line antibiotics. The most resistant bacteria isolated were Pseudomonas species and the lowest was for S. saprophyticus. The results highlighted the need for knowledge about antibiotic susceptibility profile of the bacteria causing UTI prior to antibiotic prescription in order to ensure optimal treatment.
description: EXCLI Journal;Vol. 16 2017
Immunization enhances the natural antibody repertoire
Creators: name: Beinart, Dylan
name: Ren, Daniel
name: Pi, Cinthia
name: Poulton, Susan
name: Holzknecht, Zoie E.
name: Swanson, Chelsea
name: Parker, William
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: immunology
subject: cancer
subject: vaccination
subject: vaccine
subject: 610

description: The role of immunization in the production of antibodies directed against immunogens is widely appreciated in laboratory animals and in humans. However, the role of immunization in the development of “natural antibodies” has not been investigated. Natural antibodies are those antibodies present without known history of infection or immunization, and react to a wide range of targets, including “cryptic” self-antigens that are exposed upon cell death. In this study, the ability of immunization to elicit the production of natural antibodies in laboratory rats was evaluated. Laboratory rats were immunized with a series of injections using peanut extracts (a common allergen), a high molecular weight protein conjugated to hapten (FITC-KLH), and a carbohydrate conjugated to hapten (DNPFicall). Significantly greater binding of antibodies from immunized animals compared to controls was observed to numerous autologous organ extracts (brain, kidney, liver, lung, prostate, and spleen) for both IgM and IgG, although the effect was more pronounced for IgM. These studies suggest that immunization may have at least one unforeseen benefit, enhancing networks of natural antibodies that may be important in such processes as wound repair and tumor surveillance. Such enhancement of natural antibody function may be particularly important in Western society, where decreased exposure to the environment may be associated with a weakened natural antibody repertoire.
description: EXCLI Journal;Vol. 16 2017