cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The RATAN-600 multi-frequency catalogue of blazars -- BLcat
Creators: name: Sotnikova, Yu.
name: Mufakharov, T.
name: Udovitskiy, R.
name: Mingaliev, M.
name: Semenova, T.
name: Erkenov, A.
name: Bursov, N.
name: Mikhailov, A.
name: Cherepkova, Yu.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: In this paper we present the RATAN-600 multi-frequency catalogue of blazars, an updated version of the BLcat: the RATAN-600 multi-frequency catalogue of BL Lacertae objects. The main novelty in the catalogue is an extension of the sample with flat-spectrum radio quasars (FSRQs), thus currently it contains more than 1700 blazars of different types. The main feature of the BLcat is a compilation of radio continuum data for blazars based on the RATAN-600 quasi-simultaneous measurements at frequencies of 1.2, 2.3, 4.7, 7.7/8.2, 11.2, and 21.7/22.3 GHz. We additionally supplement the catalogue with the radio data from external sources to provide an opportunity to more complete study of radio spectra and radio light curves. For the convenience of users, we developed tools to calculate the spectral index, variability index, and radio luminosity. We briefly describe basic radio properties of blazar subsamples of the catalogue: spectral classification, spectral indices, flux density variability, and radio luminosity.
description: 9 pages, 8 figures
The effect of antipsychotics on glutamate levels in the anterior cingulate cortex and clinical response: A 1H-MRS study in first-episode psychosis patients.
Creators: name: Zahid, Uzma
name: McCutcheon, Robert A
name: Borgan, Faith
name: Jauhar, Sameer
name: Pepper, Fiona
name: Nour, Matthew M
name: Rogdaki, Maria
name: Osugo, Martin
name: Murray, Graham K
name: Hathway, Pamela
name: Murray, Robin M
name: Howes, Oliver D
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Psychiatry
spectroscopy
NMDA
imaging and schizophrenia
CSF-correction
longitudinal
glutamate

description: Introduction: Glutamatergic dysfunction is implicated in the pathophysiology of schizophrenia. It is unclear whether glutamatergic dysfunction predicts response to treatment or if antipsychotic treatment influences glutamate levels. We investigated the effect of antipsychotic treatment on glutamatergic levels in the anterior cingulate cortex (ACC), and whether there is a relationship between baseline glutamatergic levels and clinical response after antipsychotic treatment in people with first episode psychosis (FEP). Materials and methods: The sample comprised 25 FEP patients; 22 completed magnetic resonance spectroscopy scans at both timepoints. Symptoms were assessed using the Positive and Negative Syndrome Scale (PANSS). Results: There was no significant change in glutamate [baseline 13.23 ± 2.33; follow-up 13.89 ± 1.74; t(21) = -1.158, p = 0.260], or Glx levels [baseline 19.64 ± 3.26; follow-up 19.66 ± 2.65; t(21) = -0.034, p = 0.973]. There was no significant association between glutamate or Glx levels at baseline and the change in PANSS positive (Glu r = 0.061, p = 0.777, Glx r = -0.152, p = 0.477), negative (Glu r = 0.144, p = 0.502, Glx r = 0.052, p = 0.811), general (Glu r = 0.110, p = 0.607, Glx r = -0.212, p = 0.320), or total scores (Glu r = 0.078, p = 0.719 Glx r = -0.155, p = 0.470). Conclusion: These findings indicate that treatment response is unlikely to be associated with baseline glutamatergic metabolites prior to antipsychotic treatment, and there is no major effect of antipsychotic treatment on glutamatergic metabolites in the ACC.
Quantum Simulation of the Radical Pair Dynamics of the Avian Compass
Creators: name: Zhang, Yiteng
name: Hu, Zixuan
name: Wang, Yuchen
name: Kais, Sabre
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The simulation of open quantum dynamics on quantum circuits has attracted wide interests recently with a variety of quantum algorithms developed and demonstrated. Among these, one particular design of a unitary-dilation-based quantum algorithm is capable of simulating general and complex physical systems. In this paper, we apply this quantum algorithm to simulating the dynamics of the radical pair mechanism in the avian compass. This application is demonstrated on the IBM QASM quantum simulator. This work is the first application of any quantum algorithm to simulating the radical pair mechanism in the avian compass, which not only demonstrates the generality of the quantum algorithm, but also opens new opportunities for studying the avian compass with quantum computing devices.
description: 7 pages, 4 figures
Conditions for Estimation of Sensitivities of Voltage Magnitudes to Complex Power Injections
Creators: name: Talkington, Samuel
name: Turizo, Daniel
name: Grijalva, Santiago
name: Fernandez, Jorge
name: Molzahn, Daniel K.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Systems and Control (eess.SY)
subject: Optimization and Control (math.OC)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Mathematics

description: Voltage phase angle measurements are often unavailable from sensors in distribution networks and transmission network boundaries. Therefore, this paper addresses the conditions for estimating sensitivities of voltage magnitudes with respect to complex (active and reactive) electric power injections based on sensor measurements. These sensitivities represent submatrices of the inverse power flow Jacobian. We extend previous results to show that the sensitivities of a bus voltage magnitude with respect to active power injections are unique and different from those with respect to reactive power. The classical Newton-Raphson power flow model is used to derive a novel representation of bus voltage magnitudes as an underdetermined linear operator of the active and reactive power injections; parameterized by the bus power factors. Two conditions that ensure the existence of unique complex power injections given voltage magnitudes are established for this underdetermined linear system, thereby compressing the solution space. The first is a sufficient condition based on the bus power factors. The second is a necessary and sufficient condition based on the system eigenvalues. We use matrix completion theory to develop estimation methods for recovering sensitivity matrices with varying levels of sensor availability. Simulations verify the results and demonstrate engineering use of the proposed methods.
description: 14 pages, 10 figures. Code corresponding to this work is publicly available at https://github.com/samtalki/PowerSensitivities.jl
Mother-Daughter Relationships in Young Adult Literature:  A Content Analysis of Adolescent Individuation
Creators: name: Gransee, Sarah M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008
Subjects: Young adult literature--Psychological aspects
Content analysis--Young adult literature--Identity(psychology)in adolescence
Young adult literature--Evaluation
Adolescence in literature--Adolescence--Psychology

description: This study describes a content analysis of young adult literature. Eight novels were selected and examined in regards to mother-daughter relationships and the presentation of daughters' individuation. The focus of this paper is the presence of emotional separation due to daughters' wishes to be independent from mothers. Based on the findings, novels in young adult literature do not present the process of individuation for adolescent daughters; rather, characters are either fully individuated at the start of the narrative or they struggle to begin their self-actualization throughout the novel. While daughters begin their individuation, their emotional evolutions are marked by strained relationships with their mothers.
The Effectiveness of Dental Sealant Program among Schoolchildren in Thailand:Systematic Review and Meta-analysis
Creators: name: Tianviwat, Sukanya
Publisher: name: The Dental Association of Thailand
Year: 2023
Subjects: Dental Sealant
Complete retention
Primary school children
Effectiveness
Caries

description: Journal of The Dental Association of Thailand, 73, 3, 199-211
SHELF-LIFE OF FRESH SALMON (SALMO SALAR) WITH LEMON JUICE STOREDAT NORMAL AND ABUSIVE TEMPERATUREShttps://www.uni-bonn.de/veranstaltungen/6th-internationale-cold-chain-management-conference/no_translated_content?set_language=de
Creators: name: M.M. de Almeida, Jose Manuel
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 300605
subject: Food safety, traceability, certification and authenticity

description: The aim of this work was to estimate the onset of spoilage of fresh Atlantic salmon (Salmo salar) fillets stored at 3 and 8°C, under different atmospheres with addiction of lemon juice.
A spatially resolved radio spectral study of the galaxy M 51
Creators: name: Gajović, L.
name: Adebahr, B.
name: Basu, A.
name: Heesen, V.
name: Brüggen, M.
name: de Gasperin, F.
name: Lara-Lopez, M. A.
name: Oonk, J. B. R.
name: Edler, H. W.
name: Bomans, D. J.
name: Paladino, R.
name: Garduño, L. E.
name: López-Cruz, O.
name: Stein, M.
name: Fritz, J.
name: Piotrowska, J.
name: Sinha, A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Radio continuum emission from galaxies at gigahertz frequencies can be used as an extinction-free tracer of star formation. However, at frequencies of a few hundred megahertz, there is evidence for low-frequency spectral flattening. We wish to better understand the origin of this low-frequency flattening and, to this end, perform a spatially resolved study of the nearby spiral galaxy M 51. We explore the different effects that can cause flattening of the spectrum towards lower frequencies, such as free-free absorption and cosmic-ray ionisation losses. We used radio continuum intensity maps between 54 and 8350 MHz at eight different frequencies, with observations at 240 MHz from the Giant Metrewave Radio Telescope presented for the first time. We corrected for contribution from thermal free-free emission using an H$α$ map that has been extinction-corrected with 24 $μ$m data. We fitted free-free absorption models to the radio spectra to determine the emission measure (EM) as well as polynomial functions to measure the non-thermal spectral curvature. The non-thermal low-frequency radio continuum spectrum between 54 and 144 MHz is very flat and even partially inverted, particularly in the spiral arms; contrary, the spectrum at higher frequencies shows the typical non-thermal radio continuum spectrum. However, we do not find any correlation between the EMs calculated from radio and from H$α$ observations; instead, the non-thermal spectral curvature weakly correlates with the HI gas mass surface density. This suggests that cosmic-ray ionisation losses play an important role in the low-frequency spectral flattening. The observed spectral flattening towards low frequencies in M 51 is caused by a combination of ionisation losses and free-free absorption. The reasons for this flattening need to be understood in order to use sub-GHz frequencies as a star-formation tracer.
Dental Service Cost of Three Oral Health Service Delivery Models in ContractedUnit of Primary Care: Provider Perspective
Creators: name: Tianviwat, Sukanya
Publisher: name: The Dental Association of Thailand
Year: 2023
Subjects: Contracted Unit of Primary Cares (CUPs)
Provider cost
Oral health service model

description: Journal of The Dental Association of Thailand, 73, 3, 212-220
Structural, electronic, and optical properties of $m$-plane InGaN/GaN quantum wells: Insights from experiment and atomistic theory
Creators: name: Schulz, S.
name: Tanner, D. P.
name: O'Reilly, E. P.
name: Caro, M. A.
name: Martin, T. L.
name: Bagot, P. A. J.
name: Moody, M. P.
name: Tang, F.
name: Griffiths, J. T.
name: Oehler, F.
name: Kappers, M. J.
name: Oliver, R. A.
name: Humphreys, C. J.
name: Sutherland, D.
name: Davies, M. J.
name: Dawson, P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In this paper we present a detailed analysis of the structural, electronic, and optical properties of an $m$-plane (In,Ga)N/GaN quantum well structure grown by metal organic vapor phase epitaxy. The sample has been structurally characterized by x-ray diffraction, scanning transmission electron microscopy, and 3D atom probe tomography. The optical properties of the sample have been studied by photoluminescence (PL), time-resolved PL spectroscopy, and polarized PL excitation spectroscopy. The PL spectrum consisted of a very broad PL line with a high degree of optical linear polarization. To understand the optical properties we have performed atomistic tight-binding calculations, and based on our initial atom probe tomography data, the model includes the effects of strain and built-in field variations arising from random alloy fluctuations. Furthermore, we included Coulomb effects in the calculations. Our microscopic theoretical description reveals strong hole wave function localization effects due to random alloy fluctuations, resulting in strong variations in ground state energies and consequently the corresponding transition energies. This is consistent with the experimentally observed broad PL peak. Furthermore, when including Coulomb contributions in the calculations we find strong exciton localization effects which explain the form of the PL decay transients. Additionally, the theoretical results confirm the experimentally observed high degree of optical linear polarization. Overall, the theoretical data are in very good agreement with the experimental findings, highlighting the strong impact of the microscopic alloy structure on the optoelectronic properties of these systems.
description: 13 pages, 12 figures
Mining for sustainability in cloud architecture among the discussions of software practitioners: building a dataset
Creators: name: Ahmadisakha, Sahar
name: Andrikopoulos, Vasilios
Publisher: name: arXiv
Year: 2024
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: The adoption of cloud computing is steadily increasing in designing and implementing software systems, thus it becomes imperative to consider the sustainability implications of these processes. While there has already been some academic research on this topic, there is a lack of perspective from practitioners. To bridge this gap, we utilize software repository mining techniques to examine 192 discussions among practitioners on the Software Engineering forum of the StackExchange platform, aiming to build an annotated dataset containing cloud architectural discussions and to understand the current discussion on sustainability in cloud architecture. To identify these discussions, we first put together a list of terms indicating sustainability as the topic. Our initial findings indicate practitioners mainly focus on design aspects (analysis, synthesis, and implementation) while avoiding complex activities like evaluation and maintenance. Technical sustainability is emphasized, while the economic dimension has the most discussions exclusively focused on it. This contrasts with previous academic literature, which highlighted environmental sustainability.
Triple-domain Feature Learning with Frequency-aware Memory Enhancement for Moving Infrared Small Target Detection
Creators: name: Duan, Weiwei
name: Ji, Luping
name: Chen, Shengjia
name: Zhu, Sicheng
name: Ye, Mao
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: As a sub-field of object detection, moving infrared small target detection presents significant challenges due to tiny target sizes and low contrast against backgrounds. Currently-existing methods primarily rely on the features extracted only from spatio-temporal domain. Frequency domain has hardly been concerned yet, although it has been widely applied in image processing. To extend feature source domains and enhance feature representation, we propose a new Triple-domain Strategy (Tridos) with the frequency-aware memory enhancement on spatio-temporal domain for infrared small target detection. In this scheme, it effectively detaches and enhances frequency features by a local-global frequency-aware module with Fourier transform. Inspired by human visual system, our memory enhancement is designed to capture the spatial relations of infrared targets among video frames. Furthermore, it encodes temporal dynamics motion features via differential learning and residual enhancing. Additionally, we further design a residual compensation to reconcile possible cross-domain feature mismatches. To our best knowledge, proposed Tridos is the first work to explore infrared target feature learning comprehensively in spatio-temporal-frequency domains. The extensive experiments on three datasets (i.e., DAUB, ITSDT-15K and IRDST) validate that our triple-domain infrared feature learning scheme could often be obviously superior to state-of-the-art ones. Source codes are available at https://github.com/UESTC-nnLab/Tridos.
description: This paper has accepted IEEE TGRS
Effect of Silanized Nano-alumina Reinforcement on Flexural Strength of Auto-polymerized Acrylic Resins
Creators: name: Duangjai, Uraivichaikul
Publisher: name: The Dental Association of Thailand
Year: 2023
Subjects: Auto-polymerized acrylic resins
Flexural strength
Reinforcement
Alumina
Nano-alumina

description: Journal of The Dental Association of Thailand, 73, 3, 221-231
Tests of general relativity at the fourth post-Newtonian order
Creators: name: Roy, Poulami Dutta
name: Datta, Sayantani
name: Arun, K. G.
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The recently computed post-Newtonian (PN) gravitational-wave phasing up to 4.5PN order accounts for several novel physical effects in compact binary dynamics such as the {\it tail of the memory, tails of tails of tails and tails of mass hexadecupole and current octupole moments}. Therefore, it is instructive to assess the ability of current-generation (2G) detectors such as LIGO/Virgo, next-generation (XG) ground-based gravitational wave detectors such as Cosmic Explorer/Einstein Telescope and space-based detectors like LISA to test the predictions of PN theory at these orders. Employing Fisher information matrix, we find that the projected bounds on the deviations from the logarithmic PN phasing coefficient at 4PN is ${\cal O}(10^{-2})$ and ${\cal O}(10^{-1})$ for XG and 2G detectors, respectively. Similarly, the projected bounds on other three PN coefficients that appear at 4PN and 4.5PN are ${\cal O}(10^{-1}-10^{-2})$ for XG and ${\cal O}(1)$ for 2G detectors. LISA observations of supermassive BHs could provide the tightest constraints on these four parameters ranging from ${\cal O}(10^{-4}-10^{-2})$. The variation in these bounds are studied as a function of total mass and the mass ratio of the binaries in quasi-circular orbits. These new tests are unique probes of higher order nonlinear interactions in compact binary dynamics and their consistency with the predictions of general relativity.
description: Matches published version. Figure and references added
Exact Results for the Moments of the Rapidity Distribution in Galilean-Invariant Integrable Models
Creators: name: Ristivojevic, Zoran
Publisher: name: arXiv
Year: 2022
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We study a class of Galilean-invariant one-dimensional Bethe ansatz solvable models in the thermodynamic limit. Their rapidity distribution obeys an integral equation with a difference kernel over a finite interval, which does not admit a closed-form solution. We develop a general formalism enabling one to study the moments of the rapidity distribution, showing that they satisfy a difference-differential equation. The derived equation is explicitly analyzed in the case of the Lieb-Liniger model and the moments are analytically calculated. In addition, we obtained the exact information about the ground-state energy at weak repulsion. The obtained results directly enter a number of physically relevant quantities.
description: 6 pages
Hidden Places, Hidden Faces: Information-Seeking and Identity-Building Behaviors of LGBTQ-identifying Americans in Russia.
Creators: name: Fish, Carson
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: In the literature about Russian LGBTQ communities, an examination of how LGBTQ-identifying foreigners — particularly Americans — navigate the unique relationship between Russia and the LGBTQ community is missing. The goal of this qualitative study was to better understand how this population made planned for their time in Russia, found LGBTQ-friendly spaces, and made decisions about “coming out.” The participants in this study used their general knowledge in Slavic studies — rather than directed, active information-seeking to form assumptions and plans about how they would present and “come out” in Russia. Many times, this meant they planned to remain “in the closet”; however, sometimes — through cultural clues — they could make an educated guess about whether or not coming out to a particular person would be a threat to their physical safety. Finally, participants who made interpersonal connections reported a higher success rate with finding LGBT-friendly spaces, such as gay bars.
Forbidden beta decay properties of $^{135,137}$Te using shell-model
Creators: name: Sharma, Shweta
name: Srivastava, Praveen C.
name: Kumar, Anil
Publisher: name: arXiv
Year: 2022
Subjects: subject: Nuclear Theory (nucl-th)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: In this work, the large-scale shell-model calculations for $β$-decay properties have been done. The $β$-delayed $γ$-ray spectroscopy has been performed recently at ILL, Grenoble [M. Si \textit{et al.}, Phys. Rev. C {\bf 106}, 014302 (2022)] to study $β$-decay properties corresponding to $^{137}$Te (($7/2^-))$ $\rightarrow$ $^{137}$I ($J_f$) transitions. We have done a systematic shell-model study for nuclear structure properties and compared the obtained results with the experimental data. Finally, the $β$-decay properties such as the $\log ft$ values and average shape factors have been reported. This is the first theoretical calculation for the $\log ft$ values corresponding to these new experimental data. In addition, we have also reported calculated $\log ft$ results for $^{135}$Te (($7/2^-))$ $\rightarrow$ $^{135}$I ($J_f$) transitions.
description: 16 pages, 1 figure, 4 tables, Accepted in Nuclear Physics A (2023)
Chiral edge transport along domain walls in magnetic topological insulator nanoribbons
Creators: name: Pournaghavi, Nezhat
name: Canali, Carlo M.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Quantum anomalous Hall insulators are topologically characterized by non-zero integer Chern numbers, the sign of which depends on the direction of the exchange field that breaks time-reversal symmetry. This feature allows the manipulation of the conducting chiral edge states present at the interface of two magnetic domains with opposite magnetization and opposite Chern numbers. Motivated by this broad understanding, the present study investigates the quantum transport properties of a magnetized $Bi_2Se_3$ topological insulator nanoribbon with a domain wall oriented either parallel or perpendicular to the transport direction. Employing an atomistic tight-binding model and a non-equilibrium Green's function formalism, we calculate the quantum conductance and explore the nature of the edge states. We elucidate the conditions leading to exact conductance quantization and identify the origin of deviations from this behavior. Our analysis shows that although the conductance is quantized in the presence of the horizontal domain wall, the quantization is absent in the perpendicular domain wall case. Furthermore, the investigation of the spin character of the edge modes confirms that the conductance in the horizontal domain wall configuration is spin polarized. This finding underscores the potential of our system as a simple three dimensional spin-filter device.
description: 9 pages, 6 figures
Testing MOND using the dynamics of nearby stellar streams
Creators: name: Koop, Orlin
name: Helmi, Amina
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The stellar halo of the Milky Way is built up, at least in part, from debris from past mergers. Stars from such merger events define substructures in phase-space, for example in the form of streams, which are groups of stars moving on similar trajectories. The nearby Helmi streams discovered more than two decades ago are a well-known example. Using 6D phase-space information from the Gaia space mission, Dodd et al. (2022) have recently reported that the Helmi streams are split into two clumps in angular momentum space. Such substructure can be explained and sustained in time if the dark matter halo of the Milky Way takes a prolate shape in the region probed by the orbits of the stars in the streams. Here, we explore the behaviour of the two clumps identified in the Helmi streams in a Modified Newtonian Dynamics (MOND) framework to test this alternative model of gravity. We perform orbit integrations of Helmi streams member stars in a simplified MOND model of the Milky Way and using the more sophisticated Phantom of RAMSES simulation framework. We find with both approaches that the two Helmi streams clumps do not retain their identity and dissolve after merely 100 Myr. This extremely short timescale would render the detection of two separate clumps as very unlikely in MONDian gravity. The observational constraints provided by the streams, which MOND fails to reproduce in its current formulation, could potentially also be used to test other alternative gravity models.
description: 10 pages, 7 figures
Ganaxolone in seizures associated with cyclin-dependent kinase-like 5 deficiency disorder: a profile of its use in the USA
Creators: name: Keam, Susan J.
name: Al-Salama, Zaina T.
Publisher: name: Adis Journals
Year: 2023
Subjects: subject: Medicine
subject: 110903 Central Nervous System
subject: FOS: Clinical medicine

description: Declarations
 Funding The preparation of this review was not supported by any external funding.
 Authorship and conflict of interest S.J. Keam is a contracted employee of Adis International Ltd/Springer Nature and declares no relevant conflicts of interest. Z.T. Al-Salama, a salaried employee of Adis International Ltd/Springer Nature and an editor of Drugs & Therapy Perspectives, was not involved in any publishing decisions for the manuscript and declares no relevant conflicts of interest. All authors contributed to the review and are responsible for the article content.
 Ethics approval, Consent to participate, Consent for publication, Availability of data and material, Code availability Not applicable.
 Additional information about this Adis Drug Review can be found here
 Abstract  Ganaxolone (ZTALMY®), a synthetic neuroactive steroid that acts as a positive allosteric modulator of the synaptic and extrasynaptic gamma-aminobutyric acid (GABA)A receptor, is an effective and well tolerated, orally-administered adjunct to existing antiseizure treatments in patients 2 years of age or older with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD)-associated seizures. CDD (a rare X-linked genetic disorder) is a severe developmental epileptic encephalopathy with onset in early infancy. In the randomized, double-blind, phase 3 Marigold trial, adjunctive ganaxolone significantly reduced the 28-day major motor seizure frequency from baseline compared with placebo in patients with CDD-associated refractory epilepsy. Preliminary results from the Marigold open-label extension suggest that the clinical benefits of ganaxolone in patients with CDD are maintained longer term. Ganaxolone is generally well tolerated; somnolence is the most frequent adverse reaction.

 © Springer Nature Switzerland AG 2023
The omega-inequality problem for concatenation hierarchies of star-free languages
Creators: name: Almeida, J.
name: Klíma, O.
name: Kunc, M.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Group Theory (math.GR)
subject: Formal Languages and Automata Theory (cs.FL)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: Primary 20M05, 20M07, Secondary 20M35, 68Q70

description: The problem considered in this paper is whether an inequality of omega-terms is valid in a given level of a concatenation hierarchy of star-free languages. The main result shows that this problem is decidable for all (integer and half) levels of the Straubing-Thérien hierarchy.
title: The Quantitative/Qualitative Debate and Feminist Research
title: A Subjective View of Objectivity
titleType: Subtitle
Creators: name: Westmarland, Nicole
Publisher: name: Humboldt-Universität zu Berlin
Year: 2001
Subjects: subject: Feminismus
subject: Wissenschaft
subject: Debatte
subject: Epistemologie
subject: 101 Theorie der Philosophie
subject: 121 Epistemologie
subject: Methode
subject: Methodologie

description: Research methods are "technique(s) for ... gathering data" (HARDING 1986) and are generally dichotomised into being either quantitative or qualitative. It has been argued that methodology has been gendered (OAKLEY 1997; 1998), with quantitative methods traditionally being associated with words such as positivism, scientific, objectivity, statistics and masculinity. In contrast, qualitative methods have generally been associated with interpretivism, non-scientific, subjectivity and femininity. These associations have led some feminist researchers to criticise (REINHARZ 1979; GRAHAM 1983; PUGH 1990) or even reject (GRAHAM & RAWLINGS 1980) the quantitative approach, arguing that it is in direct conflict with the aims of feminist research (GRAHAM 1983; MIES 1983). It has been argued that qualitative methods are more appropriate for feminist research by allowing subjective knowledge (DEPNER 1981; DUELLI KLEIN 1983), and a more equal relationship between the researcher and the researched (OAKLEY 1974; JAYARATNE 1983; STANLEY & WISE 1990). This paper considers the quantitative/qualitative divide and the epistemological reasoning behind the debate before investigating two research methods, the statistical survey and the semistructured interview, in respect of their use to feminist researchers. It concludes by arguing that different feminist issues need different research methods, and that as long as they are applied from a feminist perspective there is no need for the dichotomous "us against them", "quantitative against qualitative" debates.
The atmospheric composition of the ultra-hot Jupiter WASP-178 b observed with ESPRESSO
Creators: name: Damasceno, Y. C.
name: Seidel, J. V.
name: Prinoth, B.
name: Psaridi, A.
name: Esparza-Borges, E.
name: Stangret, M.
name: Santos, N. C.
name: Zapatero-Osorio, M. R.
name: Alibert, Y.
name: Allart, R.
name: Silva, T. Azevedo
name: Cointepas, M.
name: Silva, A. R. Costa
name: Cristo, E.
name: Di Marcantonio, P.
name: Ehrenreich, D.
name: Hernández, J. I. González
name: Herrero-Cisneros, E.
name: Lendl, M.
name: Lillo-Box, J.
name: Martins, C. J. A. P.
name: Micela, G.
name: Pallé, E.
name: Sousa, S. G.
name: Steiner, M.
name: Vaulato, V.
name: Zhao, Y.
name: Pepe, F.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We search for atmospheric constituents for the UHJ WASP-178 b with two ESPRESSO transits using the narrow-band and cross-correlation techniques, focusing on the detections of NaI, H$α$, H$β$, H$γ$, MgI, FeI and FeII. Additionally, we show parallel photometry used to obtain updated and precise stellar, planetary and orbital parameters. We report the resolved line detections of NaI (5.5 and 5.4 $σ$), H$α$ (13 $σ$), H$β$ (7.1 $σ$), and tentatively MgI (4.6 $σ$). In cross-correlation, we confirm the MgI detection (7.8 and 5.8 $σ$) and additionally report the detections of FeI (12 and 10 $σ$) and FeII (11 and 8.4 $σ$), on both nights separately. The detection of MgI remains tentative, however, due to the differing results between both nights, as well as compared with the narrow-band derived properties. None of our resolved spectral lines probing the mid- to upper atmosphere show significant shifts relative to the planetary rest frame, however H$α$ and H$β$ exhibit line broadenings of 39.6 $\pm$ 2.1 km/s and 27.6 $\pm$ 4.6 km/s, respectively, indicating the onset of possible escape. WASP-178 b differs from similar UHJ with its lack of strong atmospheric dynamics in the upper atmosphere, however the broadening seen for FeI (15.66 $\pm$ 0.58 km/s) and FeII (11.32 $\pm$ 0.52 km/s) could indicate the presence of winds in the mid-atmosphere. Future studies on the impact of the flux variability caused by the host star activity might shed more light on the subject. Previous work indicated the presence of SiO cloud-precursors in the atmosphere of WASP-178 b and a lack of MgI and FeII. However, our results suggest that a scenario where the planetary atmosphere is dominated by MgI and FeII is more likely. In light of our results, we encourage future observations to further elucidate these atmospheric properties.
description: 18 pages, 24 figures, accepted for publication in A&A
Supplementary material from A 17-year time-series of fungal environmental DNA from a coastal marine ecosystem reveals long-term seasonal-scale and inter-annual diversity patterns
Creators: name: Chrismas, Nathan
name: Allen, Ro
name: Allen, Michael J.
name: Bird, Kimberley
name: Cunliffe, Michael
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Ecology

description: Additional figures and tables referenced in the text
Keeping Up With the Times: A Comparison of Generational Internet Safety Education
Creators: name: Batten, Paul B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009
Subjects: Use studies--Internet
Internet safety

description: Internet safety has been an issue since the Internet's introduction into mainstream society. Although there was little suspected about the dangers posed by the Internet originally, many issues have come to light as the development of this resource advanced. This study describes results of an online survey of public computer users at Eva Perry Library in Apex, NC and Cameron Village Library in Raleigh, NC. The survey was conducted to assess the changes in Internet safety education of the generation that was still enrolled in school during the initial wide-spread acknowledgment of the Internet.
Color graph based wavelet transform with perceptual information
Creators: name: Malek, Mohamed
name: Helbert, David
name: Carre, Philippe
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In this paper, we propose a numerical strategy to define a multiscale analysis for color and multicomponent images based on the representation of data on a graph. Our approach consists in computing the graph of an image using the psychovisual information and analysing it by using the spectral graph wavelet transform. We suggest introducing color dimension into the computation of the weights of the graph and using the geodesic distance as a means of distance measurement. We thus have defined a wavelet transform based on a graph with perceptual information by using the CIELab color distance. This new representation is illustrated with denoising and inpainting applications. Overall, by introducing psychovisual information in the graph computation for the graph wavelet transform we obtain very promising results. Therefore results in image restoration highlight the interest of the appropriate use of color information.
Savine's citations
Creators: name: Young, Renée A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009
Subjects: Russian periodicals--Foreign countries--20th century--Bibliography
Andre Savine Collection--Bibliography
Savine, Andre, 1946-1999
Exile literature--Collections
Exiles--Russia--Federation--Bibliography

description: This project examined the bibliographic annotations made by the Parisian book dealer and noted Russian Diaspora collector André Savine. He made annotations of bibliographic and biographic information on index cards and notebook pages for the holdings of his bookstore and private collection. His annotations included citations that referred to the reference works that he used to research his acquisitions. The citations were generally abbreviated and of various levels of completeness. The goal of this project was to produce a bibliography of the reference sources used by Savine. To do this, each citation was examined and researched using WorldCat and the André Savine Collection at the University of North Carolina at Chapel Hill.
A 100 kpc Ram Pressure Tail Trailing the Group Galaxy NGC 2276
Creators: name: Roberts, I. D.
name: van Weeren, R. J.
name: de Gasperin, F.
name: Botteon, A.
name: Edler, H. W.
name: Ignesti, A.
name: Matijević, L.
name: Tomičić, N.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the discovery of a 100 kpc low-frequency radio tail behind the nearby group galaxy, NGC 2276. The extent of this tail is a factor of ten larger than previously reported from higher-frequency radio and X-ray imaging. The radio morphology of the galaxy disc and tail suggest that the tail was produced via ram-pressure stripping, cementing NGC 2276 as the clearest known example of ram-pressure stripping in a low-mass group. With multi-frequency imaging, we extract radio continuum spectra between ~50 MHz and 1.2 GHz as a function of projected distance along the tail. All of the spectra are well fit by a simple model of spectral ageing due to synchrotron and inverse-Compton losses. From these fits we estimate a velocity of 870 km/s for the stripped plasma across the plane of the sky, and a three-dimensional orbital velocity of 970 km/s for NGC 2276. The orbital speed that we derive is in excellent agreement with the previous estimate from Rasmussen et al., despite it being derived with a completely independent methodology.
description: 12 pages, 9 figures, 1 appendix, accepted for publication in A&A
Simultaneous spectral and reverberation modelling of relativistic reflection in Mrk 335
Creators: name: Chainakun, P.
name: Young, A. J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present an X-ray spectral and timing model to investigate the broad and variable iron line seen in the high flux state of Mrk 335. The model consists of a variable X-ray source positioned along the rotation axis of the black hole that illuminates the accretion disc producing a back-scattered, ionized reflection spectrum. We compute time lags including full dilution effects and perform simultaneous fitting of the 2-10 keV spectrum and the frequency-dependent time lags of 2.5-4 vs. 4-6.5 keV bands. The best-fitting parameters are consistent with a black hole mass of approximately 1.3 x 10^7 M_sun, disc inclination of 45 degrees and the photon index of the direct continuum of 2.4. The iron abundance is 0.5 and the ionization parameter is 10^3 erg cm / s at the innermost part of the disc and decreases further out. The X-ray source height is very small, approximately 2 r_g. Furthermore, we fit the Fe L lags simultaneously with the 0.3-10 keV spectrum. The key parameters are comparable to those previously obtained. We also report the differences below 2 keV using the xillver and reflionx models which could affect the interpretation of the soft excess. While simultaneously fitting spectroscopic and timing data can break the degeneracy between the source height and the black hole mass, we find that the measurements of the source height and the central mass significantly depend on the ionization state of the disc and are possibly model-dependent.
description: 11 pages, 8 figures, accepted for publication in MNRAS
Controllable non-local interactions between dark solitons in dipolar condensates
Creators: name: Bland, T.
name: Edmonds, M. J.
name: Proukakis, N. P.
name: Martin, A. M.
name: O'Dell, D. H. J.
name: Parker, N. G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We study the family of static and moving dark solitons in quasi-one-dimensional dipolar Bose-Einstein condensates, exploring their modified form and interactions. The density dip of the soliton acts as a giant anti-dipole which adds a non-local contribution to the conventional local soliton-soliton interaction. We map out the stability diagram as a function of the strength and polarization direction of the atomic dipoles, identifying both roton and phonon instabilities. Away from these instabilities, the solitons collide elastically. Varying the polarization direction relative to the condensate axis enables tuning of this non-local interaction between repulsive and attractive; the latter case supports unusual dark soliton bound states. Remarkably, these bound states are themselves shown to behave like solitons, emerging unscathed from collisions with each other.
description: 6 pages, 5 figures
Origin of modulated phases and magnetic hysteresis in TmB_4
Creators: name: Wierschem, Keola
name: Sunku, Sai Swaroop
name: Kong, Tai
name: Ito, Toshimitsu
name: Canfield, Paul C.
name: Panagopoulos, Christos
name: Sengupta, Pinaki
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We investigate the low temperature magnetic phases in TmB_4, a metallic quantum magnet on the geometrically frustrated Shastry-Sutherland lattice, using co-ordinated experimental and theoretical studies. Our results provide an explanation for the appearance of the intriguing fractional plateau in TmB_4 and accompanying magnetic hysteresis. Together with observation of the bump in the half-plateau, our results support the picture that the magnetization plateau structure in TmB_4 is strongly influenced by the zero-field modulated phases. We present a phenomenological model to explain the appearance of the modulated phases and a microscopic Hamiltonian that captures the complete magnetic behavior of TmB_4.
description: 7 pages, 5 figures
Usability Heuristic Violations, Provider Burden, and Performance During Interactions with Electronic Health Records
Creators: name: Castellano, Natalie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Electronic health records (EHRs) are widely used, but their suboptimal usability can pose risks for patient safety. This study uses data collected in a simulated environment in which providers interacted with ‘current’ and ‘enhanced’ Epic EHR interfaces to manage patients’ test results and missed appointments. Interactions were quantified and categorized by high or low burden in terms of displayed behavioral and physiological data. Using recorded video data, the interface was inspected for violations of usability heuristics, and providers’ workflow and performance was recorded. Overall, 22 heuristic violations were identified from 19 issues across all screens. Suboptimal performance was found to be associated with high burden level as well as the current EHR design. Findings can be incorporated into future design of EHRs in order to reduce providers’ burden.
Contact-interaction Faddeev equation and, inter alia, proton tensor charges
Creators: name: Xu, Shu-Sheng
name: Chen, Chen
name: Cloet, Ian C.
name: Roberts, Craig D.
name: Segovia, Jorge
name: Zong, Hong-Shi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: A confining, symmetry-preserving, Dyson-Schwinger equation treatment of a vector-vector contact interaction is used to formulate Faddeev equations for the nucleon and Delta-baryon in which the kernel involves dynamical dressed-quark exchange and whose solutions therefore provide momentum-dependent Faddeev amplitudes. These solutions are compared with those obtained in the static approximation and with a QCD-kindred formulation of the Faddeev kernel. They are also used to compute a range of nucleon properties, amongst them: the proton's sigma-term; the large Bjorken-x values of separate ratios of unpolarised and longitudinally-polarised valence u- and d-quark parton distribution functions; and the proton's tensor charges, which enable one to directly determine the effect of dressed-quark electric dipole moments (EDMs) on neutron and proton EDMs.
description: 19 pages, 5 figures, 5 tables. Includes estimate of s-quark contribution to proton tensor charge. Phys. Rev. D (in press)
Simulacro: Sobre el Ego sum de Jean-Luc Nancy
Creators: name: Benito Torres, Israel
Publisher: name: Israel Benito Torres
Year: 2024
Subjects: simulacro
filosofía

description: Debo decir que mi experiencia leyendo la obra de Jean-Luc Nancy, especialmente su libro Ego sum, me ha resultado esclarecedor, más porque me recuerda a una lectura que me dejó fascinado en su momento, Nietzsche y el círculo vicioso de Pierre Klossowski. El punto en común tanto en el libro Ego sum, como en Nietzsche y el círculo vicioso, es un rizoma entre la escritura y la pintura, ligados a la filosofía. Si bien son libros sobre autores distintos, ambos se sienten como un falso ensayo —a ésos que Klossowski nos tiene acostumbrados—, pues el punto de ambos pareciera dirigirse hacia un destino infinito, ahí donde el círculo se torna vicioso, y las ideas se repiten bajo otros nombres, donde el espíritu se manifiesta mediante la llama del conocimiento, donde la “luz proviene del caos” . Por tal motivo este escrito tiene por intención ser experimental y así crear, ante todo, un texto simulacral.