cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2 of Immunogenicity of personalized dendritic-cell therapy in HIV-1 infected individuals under suppressive antiretroviral treatment: interim analysis from a phase II clinical trial
Creators: name: de Almeida Baptista, Marcella Vassão
name: da Silva, Laís Teodoro
name: Samer, Sadia
name: Oshiro, Telma Miyuki
name: Shytaj, Iart Luca
name: Giron, Leila B.
name: Pena, Nathalia Mantovani
name: Cruz, Nicolly
name: Gosuen, Gisele Cristina
name: Ferreira, Paulo Roberto Abrão
name: Cunha-Neto, Edécio
name: Galinskas, Juliana
name: Dias, Danilo
name: Sucupira, Maria Cecilia Araripe
name: de Almeida-Neto, Cesar
name: Salomão, Reinaldo
name: da Silva Duarte, Alberto José
name: Janini, Luís Mário
name: Hunter, James R.
name: Savarino, Andrea
name: Juliano, Maria Aparecida
name: Diaz, Ricardo Sobhie
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 2: Fig. S2. Representative example of the viability of MDDCs under different maturation protocols and conditions. MDDCs were isolated from PBMCs and induced to maturation according to two protocols based on IL-4 and IFN-α as depicted in Additional file 1: Fig. S1. Maturation of MDDCs was performed starting from either freshly collected PBMCs (red bars) or PBMCs frozen in liquid nitrogen upon collection and thawed after 2 weeks. Viability was assessed by flow cytometry using a LIVE/DEAD stain. Data were normalized over the fresh-cell condition.
Entanglement Detection Based on Interference and Particle Counting
Creators: name: Toth, Geza
name: Simon, Christoph
name: Cirac, Juan Ignacio
Publisher: name: arXiv
Year: 2003
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A sufficient condition for entanglement in two-mode continuous systems is constructed based on interference visibility and the uncertainty of the total particle number. The observables to be measured (particle numbers and particle number variances) are relatively easily accessible experimentally. The method may be used to detect entanglement in light fields or in Bose-Einstein condensates. In contrast to the standard approach based on entanglement witnesses, the condition is expressed in terms of an inequality which is nonlinear in expectation values.
description: 6 pages, revtex4; an example together with a couple of paragraphs extra explanation is inserted in Sec. II.A + minor changes before publication
Elucidating the material basis and potential mechanisms of Daqinglong Decoction acting on influenza by UPLC-Q-TOF/MS and network pharmacology
Creators: name: Xiao-yan, Gong
name: Qiong-yu, Zhang
name: Si-yuan, Tang
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Daqinglong Decoction (DQLD), a traditional Chinese medicine (TCM) prescription firstly recorded in Shang han lun (the treatise on febrile diseases), has been used hundreds of years for the clinical treatment of influenza. However, the chemical composition and therapeutic mechanism of this prescription are unclear. UPLC-Q-TOF/MS was employed to analyze the chemical compounds in both methanol and boiling water extracts of DQLD. The compounds were then screened, characterized, and filtered using the TCMSP, TCMIP, TCM-ID and SymMap database, with a focus on their oral bioavailability and drug-likeness values. The resulting data were analyzed and optimized using the R language platform, Autodock and Gromacs software to identify biological processes and pathways. A total of 121 compounds were identified, of which 5 showed good binding ability to influenza virus targets (1L1B, IL10, CASP3, STAT3, TNF, and others). The active ingredient-target-influenza virus pathway was constructed using a network drug target analysis model prediction of DQLD, which was mainly enriched in Human cytomegalovirus infection, PI3K-Akt, HIF-1, and other signaling pathways through 1L1B, IL10 and other targets. Those pathways highly correlated to the body’s inflammatory response, improve immunity, and exert anti-influenza virus effects. In summary, this study demonstrated that DQLD's active ingredients can effectively bind to influenza virus targets and exert anti-influenza virus effects by reducing inflammation and improving immunity through Human cytomegalovirus infection, PI3K-Akt and HIF-1 signaling pathways. These findings offer important insights into the potential mechanisms of action of DQLD and its potential use as a TCM against influenza and other viral infections. Communicated by Ramaswamy H. Sarma
Algebraic and differential Rainich conditions for symmetric trace-free tensors of higher rank
Creators: name: Bergqvist, G.
name: Lankinen, P.
Publisher: name: arXiv
Year: 2004
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study Rainich-like conditions for symmetric and trace-free tensors T. For arbitrary even rank we find a necessary and sufficient differential condition for a tensor to satisfy the source free field equation. For rank 4, in a generic case, we combine these conditions with previously obtained algebraic conditions to obtain a complete set of algebraic and differential conditions on T for it to be a superenergy tensor of a Weyl candidate tensor satisfying the Bianchi vacuum equations. By a result of Bell and Szekeres this implies that in vacuum, generically, T must be the Bel-Robinson tensor of the spacetime. For the rank 3 case we derive a complete set of necessary algebraic and differential conditions for T to be the superenergy tensor of a massless spin 3/2 field satisfying the source free field equation.
description: 14 pages, with corrections, to appear in Proc. Roy. Soc. London A
OPERAS - Eine europäische Forschungsinfrastruktur
Creators: name: Töpfer, Marlen
Publisher: name: Zenodo
Year: 2021
Subjects: SSH
social sciences and humanities
research infrastructure
OPERAS
OPERAS-GER

description: Presentation on the OPERAS Infrastructure and Services held by OPERAS-GER with students at TH Köln on 10 May 2021.
Cosmology from Newton-Chern-Simons gravity
Creators: name: Lepe, S.
name: Rubio, G.
name: Salgado, P.
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study a five-dimensional non-relativistic gravity theory whose action is composed of a gravitational sector and a sector of matter where the gravitational sector is given by the so called Newton--Chern--Simons gravity and where the matter sector is described by a perfect fluid. At time to do cosmology, the obtained field equations shows a close analogy with the projectable version of the Hořava--Lifshitz theory in (3+1)-dimensions. Solutions and their asymptotic limits are found. In particular a phantom solution with a future singularity reminiscent of a Litlle Big Rip future singularity is obtained.
Renormalized new solutions for the massless Thirring model
Creators: name: Casana, R.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a non--perturbative study of the (1+1)--dimensional massless Thirring model by using path integral methods. The regularization ambiguities -coming from the computation of the fermionic determinant- allow to find new solution types for the model. At quantum level the Ward identity for the 1PI 2-point function for the fermionic current separates such solutions in two phases or sectors, the first one has a local gauge symmetry that is implemented at quantum level and the other one without this symmetry. The symmetric phase is a new solution which is unrelated to the previous studies of the model and, in the non--symmetric phase there are solutions that for some values of the ambiguity parameter are related to well-known solutions of the model. We construct the Schwinger--Dyson equations and the Ward identities. We make a detailed analysis of their UV divergence structure and, after, we perform a non--perturbative regularization and renormalization of the model.
description: 15 pages, LaTeX2e. Title changed, Changes in the abstract, body and conclusions. To be published in International Journal of Modern Physics A
Separating the X-Ray Emissions of UV Ceti A and B with Chandra
Creators: name: Audard, Marc
name: Guedel, Manuel
name: Skinner, Stephen L.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the first spatially separated X-ray observation of the active UV Ceti binary with \textit{Chandra}, providing important new information on the relative X-ray activity levels of its nearly identical dM5.5e components. The two components had similar X-ray luminosities during low-level periods and emission measure loci derived from Low Energy Transmission Grating spectra reveal similar coronal temperatures ($3 - 6$ MK). However, the B component showed a higher degree of variability, resulting in a higher average X-ray luminosity than that of UV Cet A. We discuss possible causes of this enhanced activity in UV Ceti B.
description: To appear in the Astrophysical Journal, Vol. 589 (2003 June 1)
Additional file 3 of Immunogenicity of personalized dendritic-cell therapy in HIV-1 infected individuals under suppressive antiretroviral treatment: interim analysis from a phase II clinical trial
Creators: name: de Almeida Baptista, Marcella Vassão
name: da Silva, Laís Teodoro
name: Samer, Sadia
name: Oshiro, Telma Miyuki
name: Shytaj, Iart Luca
name: Giron, Leila B.
name: Pena, Nathalia Mantovani
name: Cruz, Nicolly
name: Gosuen, Gisele Cristina
name: Ferreira, Paulo Roberto Abrão
name: Cunha-Neto, Edécio
name: Galinskas, Juliana
name: Dias, Danilo
name: Sucupira, Maria Cecilia Araripe
name: de Almeida-Neto, Cesar
name: Salomão, Reinaldo
name: da Silva Duarte, Alberto José
name: Janini, Luís Mário
name: Hunter, James R.
name: Savarino, Andrea
name: Juliano, Maria Aparecida
name: Diaz, Ricardo Sobhie
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 3: Fig. S3. Representative example of the maturation profile of MDDCs subjected to alternative differentiation and freezing protocols. MDDCs were isolated from PBMCs and induced to maturation according to two protocols based on IL-4 and IFN-α as depicted in Additional file 1: Fig. S1. Maturation/activation markers CD80 and HLA-DR were analyzed by flow cytometry in cells isolated from fresh PBMCs or from PBMCs thawed after freezing using FBS or a specific freezing medium (as described in the Methods section).
Quantum biochemistry description of PI3Kα enzyme bound to selective inhibitors
Creators: name: de Sousa, Francisca Joseli Freitas
name: Azevedo, Francisca Fernanda Nunes
name: de Oliveira, Francisco Lucas Santos
name: Carletti, Jaqueline Vieira
name: Freire, Valder Nogueira
name: Zanatta, Geancarlo
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer

description: The PI3K class I is composed of four PI3K isoforms that serve as regulatory enzymes governing cellular metabolism, proliferation, and survival. The hyperactivation of PI3Kα is observed in various types of cancer and is linked to poor prognosis. Unfortunately, the development inhibitors selectively targeting one of the isoforms remains challenging, with only few agents in clinical use. The main difficulty arises from the high conservation among residues at the ATP-binding pocket across isoforms, which also serves as target pocket for inhibitors. In this work, molecular dynamics and quantum calculations were performed to investigate the molecular features guiding the binding of selective inhibitors, alpelisib and GDC-0326, into the ATP-binding pocket of PI3Kα. While molecular dynamics allowed crystallographic coordinates to relax, the interaction eergy between each amino acid residues and inhibitors was obtained by combining the Molecular Fractionation with Conjugated Caps scheme with Density Functional Theory calculations. In addition, the atomic charge of ligands in the bound and unbound (free) was calculated. Results indicated that the most relevant residues for the binding of alpelisib are Ile932, Glu859, Val851, Val850, Tyr836, Met922, Ile800, and Ile848, while the most important residues for the binding of GDC-0326 are Ile848, Ile800, Ile932, Gln859, Glu849, and Met922. In addition, residues Trp780, Ile800, Tyr836, Ile848, Gln859 Val850, Val851, Ile932 and Met922 are common hotspots for both inhibitors. Overall, the results from this work contribute to improving the understanding of the molecular mechanisms controlling selectivity and highlight important interactions to be considered during the rational design of new agents. Communicated by Ramaswamy H. Sarma
The Carina Project: II. Stellar Populations
Creators: name: Monelli, M.
name: Pulone, L.
name: Corsi, C. E.
name: Castellani, M.
name: Bono, G.
name: Walker, A. R.
name: Brocato, E.
name: Buonanno, R.
name: Caputo, F.
name: Castellani, V.
name: Dall'Ora, M.
name: Marconi, M.
name: Nonino, M.
name: Ripepi, V.
name: Smith, H. A.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a new (V,B-V) Color-Magnitude Diagram (CMD) of the Carina dwarf spheroidal (dSph) that extends from the tip of the Red Giant Branch (RGB) down to about V=25 mag. Data were collected with the Wide Field Imager (WFI) available at 2.2m ESO/MPI telescope and cover an area of about 0.3 square degrees around the center of the galaxy. We confirm the occurrence of a substantial amount of old stars with ages around 11 Gyr, together with an intermediate-age population around 5 Gyr. Moreover, we also detected a new well-defined blue plume of young Main-Sequence (MS) stars with an age at most of the order of 1 Gyr. At odds with previous results available in the literature we found thatstars along the RGB of the old and of the intermediate-age stellar populationindicate a mean metallicity roughly equal to Z=0.0004 and a small dispersion around this value. We find evidence for a smooth spatial distribution of the "intermediate-age" stellar population, which appears more centrally concentrated than the oldest one.
description: 39 pages, 24 figures (PNG format). Accepted for publication on Astronomical Journal. A version with all figures included is available at http://www.mporzio.astro.it/~marco/carinaproject/
Transportation of Rice in the South: An Economic Survey
Creators: name: Limmer, Ezekiel
name: Byrne, Robert J.
name: Limmer, Ezekiel
name: Byrne, Robert J.
Publisher: name: Unknown
Year: 1956
Subjects: subject: Crop Production/Industries
subject: Marketing
subject: FOS: Economics and business

description: Excerpts from the report: During World War II, rice production in the United States was increased considerably to meet expanded requirements in the Western Hemisphere, formerly supplied in part by Asian crops. Increased demand caused farm prices to rise sharply. Production continued to rise after the war, but prices have followed a much more unsteady course than has production. After rising to a peak in 1947, farm prices fell sharply in the following 2 years. They rose again because of the Korean hostilities, reaching a second peak in 1952. Since then, prices of rice have declined. The combination of increased production and falling prices has stimulated a program in the U. S. Department of Agriculture to develop less costly or more effective marketing methods as well as other means of increasing farm income from rice. As part of this program, an economic survey of the transportation of rice was undertaken jointly by the Agricultural Marketing Service and the Farmer Cooperative Service. This survey was intended to furnish information about rice transportation which would be useful to the rice industry, the various carriers, and the general public.
Low-order multipole maps of CMB anisotropy derived from WMAP
Creators: name: Bielewicz, P.
name: Gorski, K. M.
name: Banday, A. J.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Recent analyses of the WMAP data have suggested that the low-order multipoles of the CMB anisotropy distribution show cosmologically interesting and unexpected morphologies and amplitudes. In this paper, we apply a power equalization (PE) filter to the high-latitude WMAP data in order to reconstruct these low-l multipoles free from the largest Galactic foreground modelling uncertainties in the Galactic plane. The characteristic spatial distributions of the modes of order l=2,3,4,5 have been determined as a function of frequency, sky coverage and two methods for foreground correction: using the template fitting results of Bennett et al. (2003) and by a simple linear projection scheme assuming the spectral dependence of the foreground components. Our analyses suggest that the K and Ka frequency bands remain significantly contaminated by residual foreground emission for the WMAP Kp2 mask. However, the l=3,4,5 multipole maps for the Q, V and W channels indicate that, after foreground cleaning, these multipoles are dominated by the CMB anisotropy component. We confirm the Tegmark et al. (2003) result that the octopole does indeed show structure in which its hot and cold spots are centred on a single plane in the sky, and show further that this is very stable with respect to the applied mask and foreground correction. The estimated quadrupole is much less stable showing non-negligible dependence on the Galactic foreground correction. Including these uncertainties is likely to weaken the statistical significance of the claimed alignment between the quadrupole and octopole. Nevertheless, these anisotropy patterns are also present for in COBE-DMR data, and are unlikely to be associated with instrumental systematic artifacts.
description: 21 pages, 17 figures, replaced with version accepted for publication in MNRAS, results unchanged
Spin coherence and optical properties of alkali-metal atoms in solid parahydrogen
Creators: name: Upadhyay, Sunil
name: Dargyte, Ugne
name: Dergachev, Vsevolod D.
name: Prater, Robert P.
name: Varganov, Sergey A.
name: Tscherbul, Timur V.
name: Patterson, David
name: Weinstein, Jonathan D.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a joint experimental and theoretical study of spin coherence properties of 39K, 85Rb, 87Rb, and 133Cs atoms trapped in a solid parahydrogen matrix. We use optical pumping to prepare the spin states of the implanted atoms and circular dichroism to measure their spin states. Optical pumping signals show order-of-magnitude differences depending on both matrix growth conditions and atomic species. We measure the ensemble transverse relaxation times (T2*) of the spin states of the alkali-metal atoms. Different alkali species exhibit dramatically different T2* times, ranging from sub-microsecond coherence times for high mF states of 87Rb, to ~100 microseconds for 39K. These are the longest ensemble T2* times reported for an electron spin system at high densities (n > 10^16 cm^-3). To interpret these observations, we develop a theory of inhomogenous broadening of hyperfine transitions of ^2S atoms in weakly-interacting solid matrices. Our calculated ensemble transverse relaxation times agree well with experiment, and suggest ways to longer coherence times in future work.
Insilico molecular modelling to identify PDK-1 targeting agents based on its protein–protein docking interaction
Creators: name: Vennila, Kailasam N.
name: Elango, Kuppanagounder P.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Plant Biology

description: PDK1, an attractive cancer target that downstreams 23 other kinases towards cell growth, survival and metabolism has gaining attention due to allosteric effect of ligands bound to it. Generally, the drug design strategy using pharmacophores is either a single protein structure or ensemble or ligand-based. Apart from these methods, yet another new approach of protein–protein docking with state of art computational tool like Schrodinger Suite to generate pharmacophores based on the interacting partners of the protein is proposed in this work. The structure-based pharmacophoric features were picked up from docking the ten interacting partners of PDK1 and screened against the Enamine libraries containing protein–protein interacting compound collection, advanced, protein mimetic and allosteric compounds. High throughput virtual screening against the PIF pocket of PDK1 yields an indole scaffold. The identified indole derivative is proposed to be a strong activator that binds in the protein–protein interaction site of PDK1 which was further confirmed by molecular metadynamics simulations, free energy surface analysis and MM-GBSA calculations. Thus, the pharmacophores generated by the interacting proteins for PPI can facilitate the virtual screening in structure-based drug discovery of similar therapeutic targets. Communicated by Ramaswamy H. Sarma
MOESM14 of The complete mitochondrial genome of Taxus cuspidata (Taxaceae): eight protein-coding genes have transferred to the nuclear genome
Creators: name: Kan, Sheng-Long
name: Shen, Ting-Ting
name: Gong, Ping
name: Ran, Jin-Hua
name: Wang, Xiao-Quan
Publisher: name: figshare
Year: 2020
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 14: Figure S8. Synonymous (A) and nonsynonymous (B) sequence divergence in the conserved region of mitochondrial protein-coding genes in gymnosperms. Dots indicate mitochondrial protein-coding genes that have not transferred to the nucleus in all five gymnosperm species. Circles indicate the transferred genes in Taxus and Welwitschia and their homologous genes in Cycas, Ginkgo and Pinaceae.
Additional file 1 of Impact of Dark Triad personality traits on COVID-19 vaccination uptake and prevention efforts: insights from the European Covid Survey (ECOS)
Creators: name: Bock, Sophia
name: Neumann-Böhme, Sebastian
name: Steinorth, Petra
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Computational Biology

description: Supplementary Material 1: Appendix A.
Vaccines- Intellectual Property vs Commons and Open Science
Creators: name: Caso, Roberto
Publisher: name: Zenodo
Year: 2021
Subjects: Vaccine
COVID-19
SARS-Cov_2
Intellectual Property
Open Science

description: Presentation at «Global Technology Law and Policy Seminar»
 University of Ottawa, University of Haifa, and Bocconi University
 the 5th of May 2021
MOESM6 of Comparative transcriptome analysis reveals the response mechanism of Cf-16-mediated resistance to Cladosporium fulvum infection in tomato
Creators: name: Zhang, Dongye
name: Bao, Yufang
name: Sun, Yaoguang
name: Yang, Huanhuan
name: Zhao, Tingting
name: Li, Huijia
name: Du, Chong
name: Jiang, Jingbin
name: Li, Jingfu
name: Xie, Libo
name: Xu, Xiangyang
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology
subject: Computational Biology

description: Additional file 6: Table S6. Up-regulated DEGs in the significantly enriched KEGG pathway “Plant-pathogen interaction” in Cf-16 tomato and Moneymaker at 4 dpi.
Fast radio bursts from axion stars moving through pulsar magnetospheres
Creators: name: Buckley, James H.
name: Dev, P. S. Bhupal
name: Ferrer, Francesc
name: Huang, Fa Peng
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the radio signals generated when an axion star enters the magnetosphere of a neutron star. As the axion star moves through the resonant region where the plasma-induced photon mass becomes equal to the axion mass, the axions can efficiently convert into photons, giving rise to an intense, transient radio signal. We show that a dense axion star with a mass $\sim 10^{-13}M_{\odot}$ composed of $\sim 10\: μ$eV axions can account for most of the mysterious fast radio bursts.
description: Published version in Phys. Rev. D, 6 pages, 2 figures
Additional file 4 of Immunogenicity of personalized dendritic-cell therapy in HIV-1 infected individuals under suppressive antiretroviral treatment: interim analysis from a phase II clinical trial
Creators: name: de Almeida Baptista, Marcella Vassão
name: da Silva, Laís Teodoro
name: Samer, Sadia
name: Oshiro, Telma Miyuki
name: Shytaj, Iart Luca
name: Giron, Leila B.
name: Pena, Nathalia Mantovani
name: Cruz, Nicolly
name: Gosuen, Gisele Cristina
name: Ferreira, Paulo Roberto Abrão
name: Cunha-Neto, Edécio
name: Galinskas, Juliana
name: Dias, Danilo
name: Sucupira, Maria Cecilia Araripe
name: de Almeida-Neto, Cesar
name: Salomão, Reinaldo
name: da Silva Duarte, Alberto José
name: Janini, Luís Mário
name: Hunter, James R.
name: Savarino, Andrea
name: Juliano, Maria Aparecida
name: Diaz, Ricardo Sobhie
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 4: Fig. S4. Gating strategy employed to analyze maturation markers of MDDCs
Anseropoda undetermined
Creators: name: Jangoux, Michel
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Echinodermata
Asteroidea
Valvatida
Asterinidae
Anseropoda
Anseropoda undetermined

description: * rosacea var. lobis senis, Lamarck, 1816, Asterias
Asterias rosacea var. lobis senis Lamarck, 1816: 558.
Anseropoda sp. ‒ Jangoux 2021: 242.
CURRENT STATUS. — Nomen dubium recognized as Anseropoda sp.
REMARK
Original drawings of lobis senis variety are presented in Jangoux (2021: 244 fig. 34).
The name lobis senis means “with six lobes”.
description: Published as part of Jangoux, Michel, 2022, The type specimens of extant asteroids (Echinodermata) in the Muséum national d'Histoire naturelle of Paris, pp. 259-334 in Zoosystema 44 (11) on page 313, DOI: 10.5252/zoosystema2022v44a11, http://zenodo.org/record/6616817
Additional file 3 of Impact of Dark Triad personality traits on COVID-19 vaccination uptake and prevention efforts: insights from the European Covid Survey (ECOS)
Creators: name: Bock, Sophia
name: Neumann-Böhme, Sebastian
name: Steinorth, Petra
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Computational Biology

description: Supplementary Material 3: Appendix C.
Introducing of novel class of pyrano[2,3-c]pyrazole-5-carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic and CNS toxicity profiles supported by molecular dynamic simulation
Creators: name: Almaghrabi, Mohammed
name: Musa, Arafa
name: Aljohani, Ahmed K. B.
name: Ahmed, Hany E. A.
name: Alsulaimany, Marwa
name: Miski, Samar F.
name: Mostafa, Ehab M.
name: Hussein, Shaimaa
name: Parambi, Della Grace Thomas
name: Ghoneim, Mohammed M.
name: Elgammal, Walid E.
name: Halawa, Ahmed H.
name: Hammad, Ali
name: El-Agrody, Ahmed M.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Microbiological DNA gyrase is recognized as an exceptional microbial target for the innovative development of low-resistant and more effective antimicrobial drugs. Hence, we introduced a one-pot facile synthesis of a novel pyranopyrazole scaffold bearing different functionalities; substituted aryl ring, nitrile, and hydroxyl groups. All new analogs were characterized with full spectroscopic data. The antimicrobial screening for all analogs was assessed against standard strains of Gm + ve and Gm-ve through in vitro considers. The screened compounds displayed very promising MIC/MBC values against some of the bacterial strains with broad or selective antibacterial effects. Of these, 4j biphenyl analog showed 0.5-2/2-8 µg/mL MIC/MBC for suppression and killing of Gm + ve and Gm-ve strains. Moreover, the antimicrobial screening was assessed for the most potent analogs against certain highly resistant microbial strains. Consequently, DNA gyrase supercoiling assay was done for all analogs using ciprofloxacin as reference positive control. Obviously, the results showed a different activity profile with potent analog 4j with IC50 value 6.29 µg/mL better than reference drug 10.2 µg/mL. Additionally, CNS toxicity testing was done using the HiB5 cell line for attenuation of GABA/NMDA expression to both 4j and ciprofloxacin compounds that revealed better neurotransmitter modulation by novel scaffold. Importantly, docking and dynamic simulations were performed for the most active 4j analog to investigate its interaction with DNA binding sites, which supported the in vitro observations and compound stability with binding pocket. Finally, a novel scaffold pyranopyrazole was introduced as a DNA gyrase inhibitor with prominent antibacterial efficacy and low CNS side effect toxicity better than quinolones. Communicated by Ramaswamy H. Sarma
Properties of continuous Fourier extension of the discrete cosine transform and its multidimensional generalization
Creators: name: Atoyan, A.
name: Patera, J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 65T40, 65T50, 94A08

description: A versatile method is described for the practical computation of the discrete Fourier transforms (DFT) of a continuous function $g(t)$ given by its values $g_{j}$ at the points of a uniform grid $F_{N}$ generated by conjugacy classes of elements of finite adjoint order $N$ in the fundamental region $F$ of compact semisimple Lie groups. The present implementation of the method is for the groups SU(2), when $F$ is reduced to a one-dimensional segment, and for $SU(2)\times ... \times SU(2)$ in multidimensional cases. This simplest case turns out to result in a transform known as discrete cosine transform (DCT), which is often considered to be simply a specific type of the standard DFT. Here we show that the DCT is very different from the standard DFT when the properties of the continuous extensions of these two discrete transforms from the discrete grid points $t_j; j=0,1, ... N$ to all points $t \in F$ are considered. (A) Unlike the continuous extension of the DFT, the continuous extension of (the inverse) DCT, called CEDCT, closely approximates $g(t)$ between the grid points $t_j$. (B) For increasing $N$, the derivative of CEDCT converges to the derivative of $g(t)$. And (C), for CEDCT the principle of locality is valid. Finally, we use the continuous extension of 2-dimensional DCT to illustrate its potential for interpolation, as well as for the data compression of 2D images.
description: submitted to JMP on April 3, 2003; still waiting for the referee's Report
Livestock Auction Markets in the Southeast: Methods and Facilities
Creators: name: Turner, George E.
name: Brasington, Clayton F.
name: Turner, George E.
name: Brasington, Clayton F.
Publisher: name: Unknown
Year: 1956
Subjects: subject: Livestock Production/Industries
subject: Marketing
subject: FOS: Economics and business
subject: Research and Development/Tech Change/Emerging Technologies
subject: Research Methods/ Statistical Methods

description: Excerpts from the report Introduction: Today auction markets are the most important agency in the marketing of livestock in the region. With minor exceptions, more than half of every class of livestock marketed is sold at an auction market. These markets serve the largest number of producers and also handle the largest volume of livestock. With few exceptions, auction markets in the Southeast sell all species of livestock. However, the number of horses, mules, goats, and sheep handled is comparatively small. Cattle and hogs are handled by at least 95 percent of the markets. Only a few auctions sell cattle only or hogs only. The purpose of the research reported here was: (1) To design improved livestock auction market facilities, (2) to determine the extent to which established market practices affect facility layouts and designs, and (3) to develop more efficient methods for receiving, selling and loading livestock at auction markets. In this research 20 markets were selected for case study in different geographical areas. Five auctions were selected in each of the following States: Mississippi, Florida, Georgia, and Louisiana. Data were obtained through time studies and analyses of methods at each market. In addition, a layout and flow diagram of several of the facilities was prepared. Selected operations and the facilities at a number of other markets also were studied.
Additional file 1 of pH- and acoustic-responsive platforms based on perfluoropentane-loaded protein nanoparticles for ovarian tumor-targeted ultrasound imaging and therapy
Creators: name: Jianping Li
name: Ji, Hong
name: Jing, Yong
name: Shiguang Wang
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Figure S1. The FT-IR spectrum of FA-FRT. Figure S2. The statistical data of FITC fluorescence signal inside HUM-CELL-0088 cells treated with free FITC and FITC labeled FRT-PFP, FA-FRT-PFP + FA and FA-FRT-PFP. Figure S3. Cell viabilities of HUM-CELL-0088 cells treated with 40 μg/ml of PBS (control), FRT-PFP, FA-FRT-PFP + FA and FA-FRT-PFP combined with or without LIFU irradiation (2.0 W/cm2, 4 min) and further 21 h incubation. Figure S4. The TNF protein expression level of cells treated with 40 μg/mL of PBS (control), FRT-PFP, FA-FRT-PFP + FA and FA-FRT-PFP combined with or without LIFU irradiation (2.0 W/cm2, 4 min) and further 21 h incubation.
Crowd Video Captioning
Creators: name: Yan, Liqi
name: Zhu, Mingjian
name: Yu, Changbin
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Describing a video automatically with natural language is a challenging task in the area of computer vision. In most cases, the on-site situation of great events is reported in news, but the situation of the off-site spectators in the entrance and exit is neglected which also arouses people's interest. Since the deployment of reporters in the entrance and exit costs lots of manpower, how to automatically describe the behavior of a crowd of off-site spectators is significant and remains a problem. To tackle this problem, we propose a new task called crowd video captioning (CVC) which aims to describe the crowd of spectators. We also provide baseline methods for this task and evaluate them on the dataset WorldExpo'10. Our experimental results show that captioning models have a fairly deep understanding of the crowd in video and perform satisfactorily in the CVC task.
Allopatiria ocellifera
Creators: name: Jangoux, Michel
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Echinodermata
Asteroidea
Valvatida
Asterinidae
Allopatiria
Allopatiria ocellifera

description: rosea Koehler & Vaney, 1906, Patiria
Patiria rosea Koehler & Vaney, 1906: 59, pl. 5, figs 3, 4.
Allopatiria ocellifera ‒ Clark & Downey 1992: 172.
CURRENT STATUS. — Allopatiria ocellifera (Gray, 1847).
TYPE MATERIAL. — Mauritania • 1 syntype; Cape Blanc; MNHN- IE-2014-27.
description: Published as part of Jangoux, Michel, 2022, The type specimens of extant asteroids (Echinodermata) in the Muséum national d'Histoire naturelle of Paris, pp. 259-334 in Zoosystema 44 (11) on page 313, DOI: 10.5252/zoosystema2022v44a11, http://zenodo.org/record/6616817
Additional file 6 of Immunogenicity of personalized dendritic-cell therapy in HIV-1 infected individuals under suppressive antiretroviral treatment: interim analysis from a phase II clinical trial
Creators: name: de Almeida Baptista, Marcella Vassão
name: da Silva, Laís Teodoro
name: Samer, Sadia
name: Oshiro, Telma Miyuki
name: Shytaj, Iart Luca
name: Giron, Leila B.
name: Pena, Nathalia Mantovani
name: Cruz, Nicolly
name: Gosuen, Gisele Cristina
name: Ferreira, Paulo Roberto Abrão
name: Cunha-Neto, Edécio
name: Galinskas, Juliana
name: Dias, Danilo
name: Sucupira, Maria Cecilia Araripe
name: de Almeida-Neto, Cesar
name: Salomão, Reinaldo
name: da Silva Duarte, Alberto José
name: Janini, Luís Mário
name: Hunter, James R.
name: Savarino, Andrea
name: Juliano, Maria Aparecida
name: Diaz, Ricardo Sobhie
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 6: Fig. S6. Cytokine expression in SEB/brefeldin-stimulated CD4+ and CD8+ T-lymphocytes following MDDC MDDCT. Data were obtained as described in Fig. 3.
Measurement of Anti-Deuteron Photoproduction and a Search for Heavy Stable Charged Particles at HERA
Creators: name: H1 Collaboration
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The cross section for anti-deuteron photoproduction is measured at HERA at a mean centre-of-mass energy of W_{γp} = 200 GeV in the range 0.2 < p_T/M < 0.7 and |y| < 0.4, where M, p_T and y are the mass, transverse momentum and rapidity in the laboratory frame of the anti-deuteron, respectively. The numbers of anti-deuterons per event are found to be similar in photoproduction to those in central proton-proton collisions at the CERN ISR but much lower than those in central Au-Au collisions at RHIC. The coalescence parameter B_2, which characterizes the likelihood of anti-deuteron production, is measured in photoproduction to be 0.010 \pm 0.002 \pm 0.001, which is much higher than in Au-Au collisions at a similar nucleon-nucleon centre-of-mass energy. No significant production of particles heavier than deuterons is observed and upper limits are set on the photoproduction cross sections for such particles.
description: 24 pages, 7 figures and 3 tables
Numerical method for integro-differential generalized Langevin and master equations
Creators: name: Wilkie, Joshua
Publisher: name: arXiv
Year: 2003
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We show that integro-differential generalized Langevin and non-Markovian master equations can be transformed into larger sets of ordinary differential equations. .On the basis of this transformation we develop a numerical method for solving such integro-differential equations. Physically motivated example calculations are performed to demonstrate the accuracy and convergence of the method.
description: 4 pages, 7 figures
Astropecten polyacanthus Muller & Troschel 1842
Creators: name: Jangoux, Michel
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Echinodermata
Asteroidea
Paxillosida
Astropectinidae
Astropecten
Astropecten polyacanthus

description: samoensis Perrier, 1869, Astropecten
Astropecten samoensis Perrier, 1869: 104.
Astropecten polyacanthus ‒ Clark 1989: 268.
CURRENT STATUS. — Astropecten polyacanthus Müller & Troschel, 1842.
TYPE MATERIAL. — Samoa • holotype; L’Astrolabe & La Zélée expedition (1837-1840); Hombron & Jacquinot leg.; MNHN-IE-2014-340.
description: Published as part of Jangoux, Michel, 2022, The type specimens of extant asteroids (Echinodermata) in the Muséum national d'Histoire naturelle of Paris, pp. 259-334 in Zoosystema 44 (11) on pages 313-314, DOI: 10.5252/zoosystema2022v44a11, http://zenodo.org/record/6616817
Methods of Increasing Labor Productivity in Multistory and Small One-Floor Grocery Warehouses
Creators: name: Bouma, John C.
name: Lundquist, Arnold L.
name: Bouma, John C.
name: Lundquist, Arnold L.
Publisher: name: Unknown
Year: 1956
Subjects: Labor and Human Capital
Productivity Analysis
Research and Development/Tech Change/Emerging Technologies
Research Methods/ Statistical Methods

description: Excerpts from the report Summary: The number of man-hours required in warehousing was reduced an average of 19 percent in 4 multistory and in 5 small 1-floor (less than 40,000 square feet) wholesale grocery warehouses studied, through improved work methods, use of better materials-handling equipment, improved physical layouts, and more nearly balanced work crews. Additional man-hour savings of 36 percent, for a total saving of 55 percent, can be expected after new facilities are constructed for 4 firms and recommended equipment is installed and in operation in 3 other firms. Since warehouse labor accounts for more than 50 percent of the total warehousing cost, methods of increasing productivity are of major concern to warehouse management. During this study, the following objectives were given primary consideration: (1) Evaluation of present methods and development of new methods for use by wholesale grocers for increasing warehouse labor productivity in receiving merchandise, selecting orders, checking, and loading assembled orders; (2) to show the effect of improved methods on warehouse labor costs; and (3) to show by case study analysis the problems involved in determining whether a new warehouse or new equipment should be acquired.
Additional file 5 of Immunogenicity of personalized dendritic-cell therapy in HIV-1 infected individuals under suppressive antiretroviral treatment: interim analysis from a phase II clinical trial
Creators: name: de Almeida Baptista, Marcella Vassão
name: da Silva, Laís Teodoro
name: Samer, Sadia
name: Oshiro, Telma Miyuki
name: Shytaj, Iart Luca
name: Giron, Leila B.
name: Pena, Nathalia Mantovani
name: Cruz, Nicolly
name: Gosuen, Gisele Cristina
name: Ferreira, Paulo Roberto Abrão
name: Cunha-Neto, Edécio
name: Galinskas, Juliana
name: Dias, Danilo
name: Sucupira, Maria Cecilia Araripe
name: de Almeida-Neto, Cesar
name: Salomão, Reinaldo
name: da Silva Duarte, Alberto José
name: Janini, Luís Mário
name: Hunter, James R.
name: Savarino, Andrea
name: Juliano, Maria Aparecida
name: Diaz, Ricardo Sobhie
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 5: Fig. S5. Gating strategy employed to analyze cytokine production in T-lymphocytes. Panels A, B. Cytokine production was determined in cells left unstimulated (A) or stimulated ex-vivo with the cell therapy peptides (B).
XMM-Newton observations of High Mass X-ray Binaries in the SMC
Creators: name: Sasaki, Manami
name: Pietsch, Wolfgang
name: Haberl, Frank
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Based on XMM-Newton EPIC data of four pointings towards the Small Magellanic Cloud (SMC), results on timing and spectral analyses of 16 known high mass X-ray binaries (HMXBs) and HMXB candidates in the SMC are presented. We confirm the pulse periods of four sources which were known to show pulsations. In addition, two new X-ray pulsars are discovered: XMMU J005605.2-722200 with P_pulse = 140.1 +/- 0.3 s and RX J0057.8-7207 with P_pulse = 152.34 +/- 0.05 s. Due to the low Galactic foreground absorption, X-ray binary systems in the Magellanic Clouds are well suited for studies of the soft component in their X-ray spectrum. Spectral analysis reveals soft emission besides a power law component in the spectra of three sources. The existence of emission lines in at least one of them corroborates the thermal nature of this emission with temperatures of 0.2 - 0.3 keV and heavy element abundances lower than solar. For the HMXB SMC X-2 which was in a low luminosity state, we determine a flux upper limit of 1.5 x 10^-14 erg cm^-2 s^-1 (0.3 - 10.0 keV). Furthermore, two new sources (XMMU J005735.7-721932 and XMMU J010030.2-722035) with hard spectrum and emission line objects as likely optical counterparts are proposed as new X-ray binary candidates.
description: 17 pages, 16 figures, accepted by A&A
Relationships between physical activity, diet and use of lipid-lowering drug therapy in cardiovascular disease
Creators: name: ADELLE MAXINE GADOWSKI
Publisher: name: Monash University
Year: 2021
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: 111716 Preventive Medicine

description: This thesis examines associations between lifestyle behaviours (physical activity and diet), lipid-lowering drug therapy (LLT) and adherence to lifestyle guidelines in Australian adults. We found that most adults do not adhere to lifestyle guidelines, irrespective of LLT status. We developed and validated a tool to measure the intake of core food groups and identified common barriers encountered by older adults to achieving recommended lifestyle behaviours. This work demonstrates the complexity of the relationship and highlights the need for targeted strategies to improve adherence to lifestyle behaviours, thereby optimising CVD risk management.
Additional file 1 of Intra-abdominal infection after tumor surgery: tigecycline combined with β-lactam antibiotics versus tigecycline alone
Creators: name: Cai, Xinfeng
name: Yan, Hongxia
name: Zhang, Wenjun
name: Zhao, Wei
name: Zhang, Lei
name: Wang, Xu
name: Wu, Xinjing
name: Hao, Zhiying
name: Guo, Jinlin
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy

description: Supplementary Material 1