cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: Table S1. of Monocot and dicot MLO powdery mildew susceptibility factors are functionally conserved in spite of the evolution of class-specific molecular features
Creators: name: Appiano, Michela
name: Catalano, Domenico
name: MartĂ­Nez, Miguel SantillĂĄn
name: Lotti, Concetta
name: Zheng, Zheng
name: Visser, Richard
name: Ricciardi, Luigi
name: Yuling Bai
name: Pavan, Stefano
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Codons under significant negative selection in PM susceptibility genes. Codon numbers refer to positions in the alignment of nine dicot MLO genes (AtMLO2, AtMLO6, AtMLO12, PsMLO1, MtMLO1, LjMLO1, CaMLO2, SlMLO1, NtMLO1) experimentally shown to act as powdery mildew susceptibility genes. Amino acid residues corresponding to each codon in barley HvMLO and pea PsMLO1 are indicated. For each residue, localization in any of the MLO protein domains, including seven transmembrane (TM) regions, three extracellular loops (E), three intracellular (I) loops, the N-terminus and the C-terminus, is indicated. Codons marked in bold are translated into class-specific residues. The threshold p-value was 0.1, representing the default value for Single-likelihood Ancestor Counting (SLAC) analysis implemented by the Datamonkey web server. (DOCX 30 kb)
Additional file 2: of Genetic predisposition to acute kidney injury â   a systematic review
Creators: name: Vilander, Laura
name: Kaunisto, Mari
name: PettilĂ¤, Ville
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: Search strategy in Embase. (PDF 33Â kb)
Cryphalus uapouensis
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus uapouensis

description: Cryphalus uapouensis (Beeson, 1935)
Ericryphalus uapouensis Beeson, 1935: 107; designated by Beeson, 1938b.
Distribution. Marquesas Islands.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 200, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
MOESM2 of Comparison of allele frequencies of Plasmodium falciparum merozoite antigens in malaria infections sampled in different years in a Kenyan population
Creators: name: Ochola-Oyier, Lynette
name: Okombo, John
name: Njoroge Wagatua
name: Ochieng, Jacob
name: Tetteh, Kevin
name: Fegan, Greg
name: Bejon, Philip
name: Marsh, Kevin
Publisher: name: Figshare
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. Merozoite gene allele frequencies in the uncomplicated malaria infections between 2007 and 2008.
Comparative efficacy and safety of cabozantinib for malignant tumors: a systematic review and meta-analysis
Creators: name: Su, Jingyang
name: Ni, Cui
name: Wu, Yuqian
name: Zhang, Jialin
name: Cai, Zelin
name: Lu, Jinhua
name: Lin, Shengyou
name: Wang, Jue
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: To provide a more comprehensive understanding of the efficacy and safety profile of cabozantinib versus placebo in malignant tumors, we conducted a systematic review and meta-analysis. This involved analyzing a collection of published randomized controlled trials to assess the outcomes. We used RevMan5.3 software to evaluate the outcomes of the collected studies. The primary outcome we focused on was progression-free survival (PFS), and the secondary outcomes included overall survival (OS) and disease control rate (DCR). Our findings revealed that compared to placebo, cabozantinib significantly extended the PFS of patients [hazard ratios (HR) 0.37, 95% confidence intervals (CI): 0.32, 0.43, p < 0.00001]. Additionally, cabozantinib improved the OS of patients [HR 0.78, 95%CI: 0.68, 0.91, p = 0.002]. While it is important to note that cabozantinib was associated with a higher likelihood of causing digestive, cutaneous, and cardiovascular related adverse events [relative risk (RR) 4.40, 95% CI: 3.10, 6.25, p < 0.00001]. Based on our analysis, cabozantinib significantly prolonged the PFS and OS of patients with malignant tumors (p < 0.01). We recommend the use of cabozantinib in treating advanced malignant tumors. However, it is important to continuously monitor and manage the drug-related adverse events. PROSPERO (No. CRD42023449261).
Additional file 1: Figure S1 of Independent effects of grazing and tide pool habitats on the early colonisation of an intertidal community on western Antarctic Peninsula
Creators: name: V. Segovia-Rivera
name: N. Valdivia
Publisher: name: Figshare
Year: 2016
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Percentage cover of dominant sessile species in King George Island. Percentage covers of each macrobenthic species were estimated in situ in 15 50 × 50 cm quadrats divided in 25 equal fields. Estimations were conduced on emergent rocks and in tide pools. (DOCX 57 kb)
Estrogen in ovarian cancer cell metastasis
Creators: name: Park, Se Hyung
Publisher: name: University of British Columbia
Year: 2008

description: Benign ovarian tumors and majority of epithelial ovarian cancers possess steroid receptors including estrogen receptors (ERs). However, the estrogen-ER signaling in ovarian carcinomas is not completely understood. Tumorigenesis is a multiple-step process involving dysregulated cell growth and metastasis. Tumor cells acquire the capacity of migration and invasion by temporal phenotypical and genotypical changes termed epithelial-mesenchymal transition (EMT). Considerable evidence implicates a mitogenic action of estrogen in early ovarian carcinogenesis. In contrast, its influence in the metastatic cascade of ovarian tumor cells remains obscure. In this study, I have focused on the role of 17β-estradiol (E2) in ovarian tumorigenesis. EMT related genes including E-cadherin, Snail, Slug, and Twist were examined. E2 treatment led to clear morphological changes and an enhanced cell migratory propensity. These morphologic and functional alterations were associated with changes in the abundance of EMT-related genes. Upon E2 stimulation, expression and promoter activity of the epithelial marker E-cadherin was strikingly suppressed, whereas EMT-associated transcription factors Snail and Slug were significantly up-regulated. This up-regulation was attributed to the increase in gene transcription activated by E2. Depletion of the endogenous Snail or Slug using small interfering RNA (siRNA) attenuated E2-mediated control in E-cadherin. In addition, the E2-induced cell migration was neutralized by Snail and Slug siRNAs, implying that both transcription factors are indispensable for the pro-metastatic actions of E2. Importantly, by using selective ER agonists as well as over-expression and siRNA approaches, it was identified that E2 triggered the metastatic behaviors exclusively through an ER⍺-dependent pathway. In contrast, overexpression of ERβ opposed the phenotypic changes and down-regulation of E-cadherin induced by ER⍺. In addition, microarray analysis was performed to characterize more putative downstream mediators of E2. Expression levels of 486 genes were found to be altered by at least 50% upon E2 treatment, and included several genes involved in oncogenesis, cell cycle control, apoptosis, signal transduction and the gene expression machinery. These candidate genes may be valuable for better delineating the ER pathways and functions. In summary, this study provides compelling arguments that estrogen can potentiate tumor progression by EMT induction, and highlight the crucial role of ER⍺ in ovarian tumorigenesis.
Cryphalus upoluensis Schedl 1951
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus upoluensis

description: Cryphalus upoluensis Schedl, 1951
Cryphalus upoluensis Schedl, 1951: 144.
Distribution. Samoan Islands.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 200, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Booth v. Rowland (2); Victoria; 1861.27
Creators: name: (:Null)
Publisher: name: The University of British Columbia
Year: 2019

description: No. of Plaint – 757 Summons; Invoice for £6.5 - Rowland is summoned to appear in court to answer the Plaintiff for the total amount of £6.14.4. The amount is due for water delivered to the Defendant by the Plaintiff to a house on Government Street.
Drug-drug interaction potential among patients with non-metastatic castration-resistant prostate cancer (nmCRPC) treated with novel androgen receptor inhibitors
Creators: name: Appukkuttan, Sreevalsa
name: Ko, Gilbert
name: Fu, Chunmay
name: Bannister, Breyanne
name: Kong, Sheldon X
name: Jhaveri, Jay
name: Freedland, Stephen J
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Non-metastatic castration-resistant prostate cancer (nmCRPC) patients are often older and use concurrent medications that increase potential for drug-drug interactions (pDDIs). This study assessed pDDI prevalence in real-world nmCRPC patients treated with apalutamide, darolutamide, or enzalutamide. Castrated prostate cancer patients without metastases prior to androgen receptor inhibitor initiation were identified retrospectively via Optum Clinformatics Data Mart claims data (8/2019-3/2021). The top 100 concomitant medications were assessed for pDDIs. Among 1,515 patients (mean age: 77 ± 8 years; mean Charlson comorbidity index 3 ± 3), 340 initiated apalutamide, 112 darolutamide, and 1,063 enzalutamide. Common concomitant medication classes were cardiovascular (80%) and central nervous system (52%). Two-thirds of patients received ≥ 5 concomitant medications; 30 (30/100 medications) pDDIs were identified for apalutamide and enzalutamide each and 2 (2/100 medications) for darolutamide. Most pDDIs had risk ratings of C or D, but 4 for apalutamide were rated X. 58% of patients on apalutamide, 5% on darolutamide, and 54% on enzalutamide had ≥ 1 identified pDDI. Results showed a higher frequency of pDDIs in patients receiving apalutamide and enzalutamide vs darolutamide. The impact of these could not be determined retrospectively. DDI risk should be carefully evaluated when discussing optimal therapy for patients with nmCRPC.
Additional file 1: of Adverse effects of extracorporeal carbon dioxide removal (ECCO2R) for acute respiratory failure: a systematic review protocol
Creators: name: Zulian Liu
name: Duarte, Rui
name: Bayliss, Sue
name: Bramley, George
name: Cummins, Carole
Publisher: name: Figshare
Year: 2016
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: PRISMA-P checklist. (PDF 233 kb)
Autors held hostage by ther creations
Creators: name: Will, Zander
name: Zander, Will
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: Théâtre
''Le jour où Mary Shelley rencontra Charlotte Brontë''

description: Présentation de la pièce “The Day Mary Shelley Met Charlotte Bronte” (''Le jour où Mary Shelley rencontra Charlotte Brontë'') d’Eduardo Manet, représentée au théâtre Society Hill Playhouse de Philadelphie.
description: Presentación de la obra “The Day Mary Shelley Met Charlotte Brontë” (“El día que Mary Shelley conoció a Charlotte Brontë”) de Eduardo Manet, interpretada en el teatro Society Hill Playhouse de Filadelfia.
description: Notes : Les trois parties de l’article, issues de trois pages différentes, sont réunis sur la même photocopie.
description: Titre de la publication : Philadelphia Gay News (PGN)
description: Périodicité : Hebdomadaire.
description: Source: EM-E1-1992-04-10
description: Source: Localisation de la ressource : Centre de Recherches Latino-Américaines (CRLA–Archivos, ITEM UMR8132). MSHS - Bât. A5, 1er étage 5 rue Théodore Lefebvre - TSA21103. 86073 Poitiers cedex 9.
description: created: 1992-04-10/1992-04-16
Additional file 3 of Common disease signatures from gene expression analysis in Huntingtonâ  s disease human blood and brain
Creators: name: Mina, Eleni
name: Roon-Mom, Willeke Van
name: Hettne, Kristina
name: Zwet, Erik Van
name: Goeman, Jelle
name: Neri, Christian
name: Hoen, Peter A.C.
name: Mons, Barend
name: Roos, Marco
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Modules in blood significantly correlated with HD. This file contains the 8 modules that were identified in blood as being correlated to the HD phenotype. The file describes each module according to the most representative annotations per semantic category (biological processes, cellular component, molecular function, disease or syndrome). (DOC 16.5 kb)
Cryphalus variolosus Schedl 1950
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus variolosus

description: Cryphalus variolosus Schedl, 1950
Cryphalus variolosus Schedl, 1950: 49.
Distribution. Fiji Islands.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 200, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Additional file 2: Figure S2. of Classification of follicular lymphoma: the effect of computer aid on pathologists grading
Creators: name: Fauzi, Mohammad
name: Pennell, Michael
name: Berkman Sahiner
name: Weijie Chen
name: ShanaâAh, Arwa
name: Hemminger, Jessica
name: Gru, Alejandro
name: Kurt, Habibe
name: Losos, Michael
name: Joehlin-Price, Amy
name: Kavran, Christina
name: Smith, Stephen
name: Nowacki, Nicholas
name: Sharmeen Mansor
name: Lozanski, Gerard
name: Gurcan, Metin
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Hematology

description: Graphical User Interface of the proposed FLAGS system. (DOCX 1052 kb)
Harris & Co. v. Miners Restaurant and Vauties (2); Victoria; 1861.23
Creators: name: (:Null)
Publisher: name: The University of British Columbia
Year: 2019

description: No. of Plaint – 719 Summons; Invoice for £6.2 - the Defendants are summoned to appear in court to answer the Plaintiff for the total amount of £6.1.4. The amount is due for various goods sold to the Defendants by the Plaintiff.
Lecture on environmental law between international law and domestic law
Creators: name: Valentini, Giorgia
Publisher: name: Zenodo
Year: 2024

description: Power point presentation of a lecture on "environmental law between international law and domestic law" given by Giorgia Valentini on 9.9.2023 in the course "Introduction to public law" at by Luiss University (Rome) within the Luiss Foundation Programme, a course for for non-Italian high school students who aim to study in Italian universities.
Cryphalus vestitus Blandford 1895
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus vestitus

description: Cryphalus vestitus Blandford, 1895
Cryphalus vestitus Blandford, 1895: 318.
Distribution. Sri Lanka.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 200, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
The effect of age, sex, and eastern cooperative oncology group performance status on the efficacy and safety of immune checkpoint inhibitors in patients with hepatocellular carcinoma: a systematic review and meta-analysis
Creators: name: Han, Cheng-Long
name: Tian, Bao-Wen
name: Yan, Lun-Jie
name: Ding, Zi-Niu
name: Liu, Hui
name: Pan, Guo-Qiang
name: Zhang, Xiao
name: Mao, Xin-Chen
name: Tan, Si-Yu
name: Li, Rui-Zhe
name: Wang, Dong-Xu
name: Dong, Zhao-Ru
name: Yan, Yu-Chuan
name: Li, Tao
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Astronomical and Space Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: The effect of age, sex, and eastern cooperative oncology group performance status (ECOG PS) on the efficacy and safety of immune checkpoint inhibitor (ICI) therapy among hepatocellular carcinoma (HCC) patients remains elusive. Thus, a meta-analysis was conducted to evaluate whether such effects exist. Eligible studies in PubMed, Embase, and Cochrane Library databases were retrieved. One-hundred-and-eleven studies involving 14,768 HCC patients were included. The findings indicated that the ECOG PS didn’t have a significant effect on the ORR and PFS in ICI-treated HCC patients (higher ECOG PS vs. lower ECOG PS: ORR: OR = 0.78, 95%CI = 0.55–1.10; PFS: HR = 1.15, 95%CI = 0.97–1.35), while those patients with a higher ECOG PS may have a worse OS (HR = 1.52, 95% CI = 1.26–1.84). There is no significant evidence of the effect of age (older vs. younger) or sex (males vs. females) on the efficacy of ICI therapy in HCC. ICI therapy in HCC should not be restricted strictly to certain patients in age or sex categories, while HCC patients with higher ECOG PS may require closer medication or follow-up strategy during ICI therapy. CRD42024518407
Cryphalus viburni Stark 1936
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus viburni

description: Cryphalus viburni Stark, 1936 *
Cryphalus viburni Stark, 1936: 151.
Distribution. China (Shaanxi), Russia.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 200, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Anillomyrma tridens Bolton
Creators: name: Eguchi, K.
name: Bui, T. V.
name: Alpert, G. D.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Anillomyrma
Anillomyrma tridens

description: Anillomyrma tridens Bolton, 1987 (Figs. 11 - 15)
Anillomyrma tridens Bolton, 1987: 274-275, 440. Holotype worker: East Malaysia: Sarawak, 4th Division, Gunong Mulu Nat. Park, RGS Exped., Long Pala, lowland rain forest in sandy soil, leg. B. Bolton, 11.X.1977 (BMNH); paratypes: workers with same data as holotype (BMNH, MCZ, MHN, NMB). Fifteen paratypes (personally donated to ACEG by B. Bolton) and 9 paratypes (MCZC) examined.
Worker diagnosis. Body sculpture absent except for hair-pits, which are most conspicuous on head and promesonotum; dorsum of head, promesonotum and gaster relatively densely covered with short suberect to decumbent hairs. Head in full-face view roughly rectangular, longer than broad; mandible with three large sharp teeth. Apical and preapical teeth close together, separated by a diastema from 3rd tooth; 3rd much larger than 2nd; antennal scape short, reaching only 7 / 10 - 3 / 4 of distance from anterior margin of clypeus to posterior margin of head; apical antennal segment more than 3 times as long as preapical segment. Dorsum of mesosoma in lateral view flat. Dorsum and posterior slope of propodeum in lateral view forming rounded outline. Petiolar peduncle in lateral view relatively slender (as in Fig. 11).
Worker measurements and indices. Holotype and 10 paratype workers (cited from Bolton 1987): CI 88 - 90, HL 0.37 - 0.39, HW 0.33 - 0.36, PW 0.24 - 0.25, SI 57 - 60, SL 0.21 - 0.23, WL 0.35 - 0.39.
Distribution. Malaysia: Sarawak.
Remarks. Anillomyrma tridens is morphologically very similar to A. decamera. The only conspicuous morphological characters separating the two species are as follows: head slightly longer than broad, masticatory margin of mandible of A. tridens having 3 distinct teeth as mentioned by Bolton (1987) (but very small 4th tooth rarely present) (Fig. 13); the 3rd tooth of A. tridens much larger than 2nd (Fig. 13); posterior slope of propodeum in lateral view expanding posterodorsad more strongly in A. tridens (Fig. 11) than in A. decamera (Fig. 1); petiolar peduncle in lateral view more slender in A. tridens (Fig. 11) than in A. decamera (Fig. 1).
description: Published as part of Eguchi, K., Bui, T. V. & Alpert, G. D., 2009, Revision of the ant genus Anillomyrma Emery, 1913 (Hymenoptera: Formicidae: Myrmicinae: Solenopsidini)., pp. 31-36 in Myrmecological News 13 on pages 33-35
MOESM3 of Identification and characterization of putative xylose and cellobiose transporters in Aspergillus nidulans
Creators: name: Thaila Reis
name: Pollyne Lima
name: Nádia Parachin
name: Mingossi, Fabiana
name: Oliveira, Juliana Castro
name: Ries, Laure
name: Goldman, Gustavo
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 2. Enzymatic kinetics. (A) Eadie–Hofstee and (B) Lineweaver–Burk plots for the data of the Fig. 6c.
Additional file 1: of An evaluation of the DEXLIFE ‘self-selected’ lifestyle intervention aimed at improving insulin sensitivity in people at risk of developing type 2 diabetes: study protocol for a randomised controlled trial
Creators: name: Grainne O’Donoghue
name: Kennedy, Aileen
name: Gregers Stig Andersen
name: Durkan, Eoin
name: Thybo, Tanja
name: Sinnott, Margaret
name: Nolan, John
name: O’Gorman, Donal
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Additional details of outcome measures used in the study. (DOCX 15 kb)
Cryphalus vitiensis Browne 1974
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus vitiensis

description: Cryphalus vitiensis Browne, 1974
Cryphalus vitiensis Browne, 1974: 67.
Distribution. Fiji Islands.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 200, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Additional file 2: of 2-Cys peroxiredoxin is required in successful blood-feeding, reproduction, and antioxidant response in the hard tick Haemaphysalis longicornis
Creators: name: Kodai Kusakisako
name: Remil Galay
name: Umemiya-Shirafuji, Rika
name: Hernandez, Emmanuel
name: Maeda, Hiroki
name: Melbourne Talactac
name: Naotoshi Tsuji
name: Mochizuki, Masami
name: Fujisaki, Kozo
name: Tanaka, Tetsuya
Publisher: name: Figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Candidates for non-specific bands from Japanese white rabbit blood in Western blot analysis. (DOCX 13 kb)
Hypergeometric functions and Mahler measure
Creators: name: Rogers, Mathew D.
Publisher: name: University of British Columbia
Year: 2008

description: The logarithmic Mahler measure of an n-variable Laurent polynomial, P(x1,...,xn) is defined by [expression]. Using experimental methods, David Boyd conjectured a large number of explicit relations between Mahler measures of polynomials and special values of different types of L-series. This thesis contains four papers which either prove or attempt to prove conjectures due to Boyd. The introductory chapter contains an overview of the contents of each manuscript.
Anillomyrma
Creators: name: Eguchi, K.
name: Bui, T. V.
name: Alpert, G. D.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Anillomyrma

description: Anillomyrma sp.
Domingo Empeso collected 5 workers of Anillomyrma from Dumaguete, Negros Island, Philippines (MCZC). Because the specimens were, however, shrunk heavily and / or covered largely with glue, we were unable to see the basal part of masticatory margin of mandibles. Thus we refrained from determining them at the species level.
description: Published as part of Eguchi, K., Bui, T. V. & Alpert, G. D., 2009, Revision of the ant genus Anillomyrma Emery, 1913 (Hymenoptera: Formicidae: Myrmicinae: Solenopsidini)., pp. 31-36 in Myrmecological News 13 on page 35
Additional file 5: Figure S5. of Classification of follicular lymphoma: the effect of computer aid on pathologists grading
Creators: name: Fauzi, Mohammad
name: Pennell, Michael
name: Berkman Sahiner
name: Weijie Chen
name: ShanaâAh, Arwa
name: Hemminger, Jessica
name: Gru, Alejandro
name: Kurt, Habibe
name: Losos, Michael
name: Joehlin-Price, Amy
name: Kavran, Christina
name: Smith, Stephen
name: Nowacki, Nicholas
name: Sharmeen Mansor
name: Lozanski, Gerard
name: Gurcan, Metin
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Reader-Specific ROC Curves. Readers 1-4 were expert hematopathologists. Readers 5-11 were residents. (DOCX 21 kb)
Microlepidieae Al-Shehbaz, Warwick, Mumm. & M.Koch 2010
Creators: name: Lysak, Martin A.
name: Edginton, Mark
name: Zuo, Sheng
name: Guo, Xinyi
name: Mandáková, Terezie
name: Al-Shehbaz, Ihsan A.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Brassicales
Brassicaceae

description: Arabidella and Lemphoria can be easily separated as follows:
1a. Shrubs or subshrubs, rarely annual herbs; lower leaves 2-, 3- or rarely multisect into linear to filiform lobes; nectar glands confluent, median glands present; ovules 20–90 per ovary; fruits linear, subterete or slightly latiseptate .......................................... Arabidella
1b. Annual herbs; lower leaves pinnatifid to pinnatisect; nectar glands lateral, not confluent, median glands absent; ovules 6–70 per ovary; fruits oblong to linear siliques, or elliptic to suborbicular silicles, subterete or angustiseptate.............................. Lemphoria
description: Published as part of Lysak, Martin A., Edginton, Mark, Zuo, Sheng, Guo, Xinyi, Mandáková, Terezie & Al-Shehbaz, Ihsan A., 2022, Transfer of two Arabidella and two Cuphonotus species to the genus Lemphoria (Brassicaceae) and a description of the new species L. queenslandica, pp. 235-240 in Phytotaxa 549 (2) on page 237, DOI: 10.11646/phytotaxa.549.2.9, http://zenodo.org/record/6622863
Additional file 1 of Common disease signatures from gene expression analysis in Huntingtonâ  s disease human blood and brain
Creators: name: Mina, Eleni
name: Roon-Mom, Willeke Van
name: Hettne, Kristina
name: Zwet, Erik Van
name: Goeman, Jelle
name: Neri, Christian
name: Hoen, Peter A.C.
name: Mons, Barend
name: Roos, Marco
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Significantly correlated modules in brain. This file contains the modules from each brain region (caudate, BA4, BA9 and cerebellum) that were associated with the disease phenotype. The numbers (P v a l u e) indicate the correlation of each module with the disease phenotype. Green: negative correlation, red: positive correlation. The intensity of the color depicts the strength of the correlation. (PDF 1341 kb)
Cryphalus walkeri
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus walkeri

description: Cryphalus walkeri (Blandford, 1896)
Cryptarthrum walkeri Blandford, 1896: 200; designated by Schedl, 1963: 62.
Coccotrypes hagedorni Eggers, 1908: 216; synonymized by Schedl, 1963: 62.
Cryphalus javanus Schedl, 1954: 148; synonymized by Schedl, 1958 k: 153.
Cryphalus mekeoi Schedl, 1972c: 61; synonymized by Schedl, 1979b: 126.
Distribution. Malaysia, Vietnam, Australia (Victoria), Indonesia (Damma, Java, Sumatra), Philippine Islands (Luzon,
Mindanao, Mindoro).
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 200, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
MOESM5 of Identification and characterization of putative xylose and cellobiose transporters in Aspergillus nidulans
Creators: name: Thaila Reis
name: Pollyne Lima
name: Nádia Parachin
name: Mingossi, Fabiana
name: Oliveira, Juliana Castro
name: Ries, Laure
name: Goldman, Gustavo
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Developmental Biology
subject: Marine Biology
subject: Plant Biology

description: Additional file 5. Genomic DNA from the A. nidulans wild-type, ΔxtrG (AN8347), ΔxtrH (AN9173), ΔcltB (AN2814) and the double ΔcltA ΔcltB strains was extracted and digested with different restriction enzymes to confirm the deletion strains. Diagram (A.) and Southern blot (B.) of the wild-type and ΔxtrG strains when digested with SacI. A 1-kb DNA fragment from the xtrG 3′UTR (untranslated) region was used as a hybridization probe. The probe recognizes a single 10.0-kb band in the wild-type strain and a single 6.4-kb band in the ΔxtrG strain. Diagram (C.) and Southern blot (D.) of the wild-type and ΔxtrH strains when digested with EcoRI. A 1-kb DNA fragment from the xtrH 5′UTR (untranslated) region was used as a hybridization probe. The probe recognizes a single 3.4-kb band in the wild-type strain and a single 3.0-kb band in the ΔxtrH strain. Diagram (E.) and Southern blot (F.) of the wild-type and ΔcltB strains when digested with XbaI. A 1-kb DNA fragment from the cltB 5′UTR (untranslated) region was used as a hybridization probe. The probe recognizes a single 2.0-kb band in the wild-type strain and a single 3.3-kb band in the ΔcltB strain. Diagram (G.) and Southern blot (H.) of the wild-type and ΔcltA ΔcltB strains when digested with KpnI. A 1-kb DNA fragment from the cltB 3′UTR (untranslated) region was used as a hybridization probe. The probe recognizes a single 2.0-kb band in the wild-type strain and a single 2.5-kb band in the ΔxtrG strain.
Arabidella Schulz 1924
Creators: name: Lysak, Martin A.
name: Edginton, Mark
name: Zuo, Sheng
name: Guo, Xinyi
name: Mandáková, Terezie
name: Al-Shehbaz, Ihsan A.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Brassicales
Brassicaceae
Arabidella

description: Following the transfer of two of the six species of Arabidella sensu Shaw (1965) to Lemphoria, the remaining species can be distinguished by the following key.
1a. Annual herbs with basal leaf rosette at least during flowering; stems without bark ...................................................... A. nasturtium
1b. Woody shrubs or subshrubs without basal leaf rosette; stems usually with some bark.
2a. Fruiting pedicel divaricate to horizontal or slightly recurved; all leaves undivided, rarely some 2- or 3-sect ................... A. filifolia
2b. Fruiting pedicels suberect to ascending, straight; almost all leaves 2-, 3-, or multisect.
3a. Stems glabrous; flowers in corymb; fruit 1–2.5 mm wide; gynophore (0.8–) 1–2.2 mm long..................................... A. glaucescens
3b. Stems often papillate; flowers in lax raceme; fruit 0.8–1.5 mm wide; gynophore 0.1–0.5 mm long ................................. A. trisecta
description: Published as part of Lysak, Martin A., Edginton, Mark, Zuo, Sheng, Guo, Xinyi, Mandáková, Terezie & Al-Shehbaz, Ihsan A., 2022, Transfer of two Arabidella and two Cuphonotus species to the genus Lemphoria (Brassicaceae) and a description of the new species L. queenslandica, pp. 235-240 in Phytotaxa 549 (2) on page 237, DOI: 10.11646/phytotaxa.549.2.9, http://zenodo.org/record/6622863
Carroll c. Wallace (2); Victoria; 1861.24
Creators: name: (:Null)
Publisher: name: The University of British Columbia
Year: 2019

description: No. of Plaint – 720 Summons; Invoice for £31.5 - Wallace is summoned to appear in court to answer the Plaintiff for the total amount of £32.13.11. The amount is due for five baskets of champagne, drinks and cigars sold to the Defendant by the Plaintiff.
Cryphalus wapleri Eichhoff 1872
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus wapleri

description: Cryphalus wapleri Eichhoff, 1872
Cryphalus wapleri Eichhoff, 1872: 131.
Distribution. Australia (Queensland), New Guinea.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 200, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Cryphalus yamaguchii Inouye & Nobuchi 1957
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus yamaguchii

description: Cryphalus yamaguchii Inouye & Nobuchi, 1957
Cryphalus yamaguchii Inouye & Nobuchi, 1957: 55.
Distribution. Japan.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on pages 200-201, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Lemphoria Schulz 1924
Creators: name: Lysak, Martin A.
name: Edginton, Mark
name: Zuo, Sheng
name: Guo, Xinyi
name: Mandáková, Terezie
name: Al-Shehbaz, Ihsan A.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Brassicales
Brassicaceae
Lemphoria

description: Lemphoria Schulz (1924: 267).
Type: L. procumbens (Tate) O.E.Schulz.
Cuphonotus Schulz (1933: 92), syn. nov. Lectotype (designated by Shaw 1974: 154): C. humistratus (F.Muell.) O.E.Schulz.
Herbs, annual. Trichomes absent or simple and slender, crisped or straight. Multicellular glands absent. Stems herbaceous, erect to ascending or decumbent, several from base, branched throughout, leafy, unarmed. Basal leaves rosulate or not, entire, pinnatifid to pinnatisect, subfleshy or not; cauline leaves more or less similar to basal leaves, short petiolate to subsessile, not auriculate at base, uppermost leaves entire. Racemes many flowered, ebracteate, corymbose, elongated considerably in fruit, rarely reduced to solitary flowers on pedicels originating from basal rosette; rachis straight; fruiting pedicels suberect to ascending or divaricate, persistent. Sepals ovate to oblong or elliptic, free, deciduous, spreading to reflexed, equal, base of lateral pair not saccate; petals white or yellow, spreading, subequaling to longer than sepals; blade oblanceolate to linear or obovate to suborbicular, apex obtuse; claw obscurely to strongly differentiated from blade, shorter than sepals, glabrous, unappendaged, entire; stamens 6, slightly exserted, erect to spreading, slightly tetradynamous; filaments wingless, unappendaged, glabrous, free, distinctly dilated at base; anthers ovate, obtuse at apex; nectar glands lateral, at both sides of lateral stamens, median glands absent; ovules 6−70 per ovary; placentation parietal. Fruit dehiscent, capsular, linear to oblong siliques or elliptic to suborbicular silicles, subterete or angustiseptate, not inflated, unsegmented; valves papery, prominently to obscurely veined, glabrous, not keeled, smooth, wingless, unappendaged; gynophore absent or obsolete; replum rounded, visible; septum complete, membranous, veinless or with an obscure midvein; style obsolete or 0.1−1 mm long, persistent; stigma capitate, entire or slightly 2-lobed, unappendaged. Seeds uniseriate or biseriate, wingless or margined, oblong to ellipsoid, plump or slightly flattened; seed coat minutely reticulate to nearly smooth, copiously mucilaginous when wetted; cotyledons incumbent.
Distribution: Endemic to Australia.
description: Published as part of Lysak, Martin A., Edginton, Mark, Zuo, Sheng, Guo, Xinyi, Mandáková, Terezie & Al-Shehbaz, Ihsan A., 2022, Transfer of two Arabidella and two Cuphonotus species to the genus Lemphoria (Brassicaceae) and a description of the new species L. queenslandica, pp. 235-240 in Phytotaxa 549 (2) on page 237, DOI: 10.11646/phytotaxa.549.2.9, http://zenodo.org/record/6622863
Cryphalus zimmermani Schedl 1950
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus zimmermani

description: Cryphalus zimmermani Schedl, 1950
Cryphalus zimmermani Schedl, 1950: 51.
Distribution. Fiji Islands.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 201, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Additional file 2: of An evaluation of the DEXLIFE ‘self-selected’ lifestyle intervention aimed at improving insulin sensitivity in people at risk of developing type 2 diabetes: study protocol for a randomised controlled trial
Creators: name: Grainne O’Donoghue
name: Kennedy, Aileen
name: Gregers Stig Andersen
name: Durkan, Eoin
name: Thybo, Tanja
name: Sinnott, Margaret
name: Nolan, John
name: O’Gorman, Donal
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy

description: Participant flow through the recruitment process. (PDF 170 kb)
Additional file 1: of Spatial patterns and secular trends in human leishmaniasis incidence in Morocco between 2003 and 2013
Creators: name: Sadeq, Mina
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Multilingual abstracts in the six official working languages of the United Nations. (PDF 502Â kb)
Lemphoria Schulz 1924
Creators: name: Lysak, Martin A.
name: Edginton, Mark
name: Zuo, Sheng
name: Guo, Xinyi
name: Mandáková, Terezie
name: Al-Shehbaz, Ihsan A.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Brassicales
Brassicaceae
Lemphoria

description: Key to Lemphoria species
1a. Fruit elliptic to suborbicular, strongly angustiseptate silicles; ovules 6−14 per ovary; seeds uniseriate.
2a. Plants pubescent; fruit valves smooth; petals 1−1.5 mm long; at least some leaves pinnatifid .................................... L. andraeana
2b. Plants glabrous to subglabrous; fruit valves conspicuously reticulate; petals 2−3 mm long; all leaves usually entire ....................... ........................................................................................................................................................................................ L. humistrata
1b. Fruit oblong or linear, subterete or slightly angustiseptate siliques; ovules 20−70 per ovary; seeds biseriate.
3a. Fruit oblong to ellipsoid, 2−2.5 mm wide; ovules 20−40 per ovary; cauline leaves broadly spatulate to obovate, 3−5-lobed........... .................................................................................................................................................................................. L. queenslandica
3b. Fruit linear, 0.6−1.4 mm wide; ovules 50−70 per ovary; cauline leaves narrowly oblanceolate, (3−)5−15-lobed.
4a. Plants pilose throughout; petals 2.5–4 × 0.9–2 mm ........................................................................................................ L. eremigena
4b. Plants glabrous; petals 1.4–2.2 × 0.4–0.7 mm .............................................................................................................. L. procumbens
description: Published as part of Lysak, Martin A., Edginton, Mark, Zuo, Sheng, Guo, Xinyi, Mandáková, Terezie & Al-Shehbaz, Ihsan A., 2022, Transfer of two Arabidella and two Cuphonotus species to the genus Lemphoria (Brassicaceae) and a description of the new species L. queenslandica, pp. 235-240 in Phytotaxa 549 (2) on page 237, DOI: 10.11646/phytotaxa.549.2.9, http://zenodo.org/record/6622863
Prevention of bacterial growth in platelet products via inclusion of iron chelators
Creators: name: Ng-Muk-Yuen, Jennifer Diane
Publisher: name: University of British Columbia
Year: 2008

description: Bacterial infection is a leading cause of morbidity and mortality arising from platelet transfusions (1, 2). Storage of platelet products at room temperature (20 to 24ºC) provides ideal conditions for bacterial proliferation (1, 3-6). Furthermore, platelets are stored in plasma containing bioavailable iron that bacteria require to survive (7). Thus we hypothesize that the inclusion of iron chelators will bind and remove iron, thereby inhibiting bacterial growth in both culture medium and platelet concentrates. Additionally, we hypothesize that residual red blood cells (RBCs) in platelet units may contribute bioavailable iron that promotes bacterial growth. To test these hypotheses, we first assessed growth of Staphylococcus epidermidis in culture medium after treatment with the iron chelators deferoxamine (DFO) or phytic acid. DFO significantly inhibited bacterial growth in a dose dependent manner (p < 0.009). Conversely, phytate only inhibited bacterial growth at concentrations ≥ 100 mM (p < 0.001); at ≤ 5 mM, phytate supplied S. epidermidis with additional nutrients and significantly promoted growth (p < 0.001). Subsequently, we monitored the change in RBCs over time. Hemolysis, methemoglobin, and iron levels all significantly increased over the 7-day storage period (p < 0.001) releasing bioavailable iron. Indeed, we found that S. epidermidis growth in iron-poor medium drastically increased with the addition of RBCs, thus supporting our second hypothesis. Surprisingly, the inclusion of DFO in minimal medium did not demonstrate a bacteriostatic effect in the presence of RBCs. The inhibitory effect of DFO was likely overcome by iron released from the elevated methemoglobin levels arising from the direct interaction of DFO with hemoglobin. Previous studies demonstrate that methemoglobin releases iron more quickly than normal hemoglobin (8). Lastly, we evaluated the effect of DFO on microbial growth in platelet concentrates using the BacT/ALERT system. The presence of DFO significantly inhibited S. epidermidis growth in buffy coat platelets in a dose dependent manner (p < 0.001). With these findings, the inclusion of iron chelators is a promising approach to preventing transfusion-transmitted bacterial infection and providing patients with a safer platelet product.