cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Historische Darstellungsformen des amerikanischen Printjournalismus und deren Adaption in Europa anhand des Beispiels Österreich
Creators: name: Posch, Eva
Year: 2009

description: New Journalism, Investigativer Journalismus und das etwas neuere Berichterstattungsmuster des Public Journalism, sollen im Mittelpunkt dieser Arbeit stehen. Seit langem scheint der Begriff der Amerikanisierung ein fester Bestandteil unserer Gesellschaft zu sein. Kann Amerika zwar bis Mitte des 19. Jahrhunderts durchaus als Importeur europäischer materieller und ideeller Produkte bezeichnet werden, veränderte sich jene Position Amerikas im Zuge eines historischen Prozesses. Musste Amerika beispielsweise im 17. Jahrhundert seine medialen Ambitionen noch auf die bloße Einfuhr europäischer Zeitungen beschränken , war es Amerika möglich bis ins 19. Jahrhundert hinein, so große Fortschritte im Bereich des Mediensektors zu machen, dass in Fachkreisen von Amerikanisierung der Medien gesprochen werden konnte. Doch welche historischen Faktoren können für jene Vorreiterrolle Amerikas nun im Einzelnen verantwortlich gemacht werden? Eine vergleichende Mediengeschichte zwischen Amerika und Österreich soll hierbei etwas Licht in die Thematik bringen. Neben Themenbereichen wie Pressefreiheit und dem Aufkommen der ersten Zeitungen in beiden Ländern, sollen auch Faktoren wie Urbanisierung und Industrialisierung nicht unbeachtet bleiben, da sie als wichtige Entwicklungskriterien des Journalismus sowohl in Österreich, als auch in Amerika angesehen werden können. Im Besonderen soll diese Arbeit zeigen, wie es zur Entwicklung von Darstellungsformen wie New Journalism, Investigativen Journalismus und Public Journalism in Amerika kam und weshalb nicht etwa ein Land wie Österreich diese Berichterstattungsmuster hervorbringen konnte. Darüber hinaus werden einige ausgewählte Beispiele, dieser journalistischen Genres, zeigen wie die Adaption des New Journalism, Investigativen Journalismus und Public Journalism in Österreich von statten ging und weshalb eine eins zu eins Übernahme hier zu Lande geradezu unmöglich war. Abschließend soll sich diese Arbeit mit der Zukunft jener weltweit bekannten Darstellungsformen beschäftigen. In Zeiten der Weltwirtschaftskrise und des Zeitungssterbens stellt man sich wohl unausweichlich die Frage, inwieweit alternative Berichterstattungsmuster, welche zweifelsohne Geld und Zeit in Anspruch nehmen, noch bestehen können. Doch sind dies wirklich die einzigen Probleme mit denen New Journalists, investigative Reporter und Public Journalists konfrontiert werden? All dies und noch mehr soll im Verlauf dieser Arbeit ausführlich untersucht werden.
uniforum 31 (2018) Nr. 3
Creators: name: (:Unkn) Unknown
name: Justus Liebig University Giessen
Publisher: name: Universitätsbibliothek Gießen
Year: 2018
Subjects: subject: ddc:000

description: Wie ein aktiver Beitrag zur Gestaltung Europas aussehen kann: Die Partnerschaft der JLU mit der Universität Lodz wurde im Jahr 1978 besiegelt und gilt bis heute als ein Musterbeispiel gelebter Völkerverständigung.Wo Pionierarbeit geleistet wird: In Gießen arbeitet der europaweit erste Forschungsverbund auf dem Gebiet der Insektenbiotechnologie. Eindrücke vom Richtfest für das geplante Fraunhofer-Institut für Bioressourcen.Wenn im Zentrum der Universitätsstadt ein Kulturviertel entsteht: Das Theaterlabor des Instituts für Angewandte Theaterwissenschaft nimmt Formen an. Die symbolische Grundsteinlegung wurde kürzlich gefeiert.Woran wir uns erinnern sollen: Die Constitutio Antoniniana ist Memory of the World . Im feierlichen Rahmen erfolgte die Übergabe der Urkunde zur Aufnahme ins UNESCO-Weltdokumentenerbe.
Layered Chirp Spread Spectrum Modulations for LPWANs
Creators: name: Azim, Ali Waqar
name: Bazzi, Ahmad
name: Bomfin, Roberto
name: Shubair, Raed
name: Chafii, Marwa
Publisher: name: arXiv
Year: 2024
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This article examines two chirp spread spectrum techniques specifically devised for low-power wide-area networks (LPWANs) to optimize energy and spectral efficiency (SE). These methods referred to as layered CSS (LCSS) and layered dual-mode CSS (LDMCSS), involves utilizing multiple layers for multiplexing symbols with varying chirp rates. These waveform designs exemplify a high degree of SE compared to existing schemes. Additionally, LDMCSS necessitates a lesser number of layers than LCSS to attain comparable SE, thereby reducing computational complexity. These proposed techniques can employ coherent and non-coherent detection and can be adjusted to achieve various spectral efficiencies by altering the number of multiplexed layers. Unlike our proposed LCSS and LDMCSS, other CSS alternatives for LPWANs cannot provide the same level of flexibility and SE. The performance of these techniques is evaluated in terms of bit error rate under different channel conditions, as well as with phase and frequency offsets.
Additional file 1 of Exploring the therapeutic potential of garlic in alcoholic liver disease: a network pharmacology and experimental validation study
Creators: name: Gao, Siqi
name: Gao, Tingting
name: Li, Lizheng
name: Wang, Shule
name: Hu, Jie
name: Zhang, Ruijing
name: Zhou, Yun
name: Dong, Honglin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Supplementary Material 1
The value of wealth: Representing contemporary corporate space
Creators: name: LEACH, Samuel
Publisher: name: RMIT University
Year: 2024

description: The objective of my research is to develop a body of work for exhibition based on an examination of the ways that corporate space, as exemplified by the foyers and conference rooms of contemporary corporate offices, reflect societal anxieties about wealth and power. These works will draw on the history of painting, with particular reference to 17th century Dutch still life painting, as a framework within which to conduct the exploration of contemporary space. This will be done by applying or interpreting the principles, motifs and techniques used in that period in the visual representation of the connection between wealth and decadence and western culture's ambiguous attitude towards the creation and accumulation of wealth. Boardrooms, corporate foyers and office interiors have developed into instantly recognisable types of space with a particular atmosphere, typified by large empty space and the use of materials such as marble and granite and surfaces with reflective finishes.. These spaces are often open to the public, but the intention is for people to be impressed by the wealth and power of the occupants, an idea initially perfected in Ancient Rome. The impression of wealth and power created in these spaces is balanced against a need to demonstrate prudence and restraint - the corporations need to avoid creating an impression of extravagance or wastefulness. The emergence of the genre still life painting in the Netherlands during the 17th century provides useful source material for their representations of restrained prosperity as well as the moral content related to the virtues of modesty and the transience of material life and wealth. The illusory space in the church interiors of Saenredam and de Witte, with their sense of expansive space and light, are echoed in the real space of contemporary corporate foyers and provide a basis for considering the format, composition and modes of representation of constructed space.
Additional file 2 of Mortality and its predictors among human immunodeficiency virus-infected children younger than 15 years receiving antiretroviral therapy in Ethiopia: a systematic review and meta-analysis
Creators: name: Woldegeorgis, Beshada Zerfu
name: Asgedom, Yordanos sisay
name: Gebrekidan, Amanuel Yosef
name: Kassie, Gizachew Ambaw
name: Borko, Ushula Deboch
name: Obsa, Mohammed Suleiman
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2
Towards Deeper Understanding of PPR-based Embedding Approaches: A Topological Perspective
Creators: name: Zhang, Xingyi
name: Weng, Zixuan
name: Wang, Sibo
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: Social and Information Networks (cs.SI)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Node embedding learns low-dimensional vectors for nodes in the graph. Recent state-of-the-art embedding approaches take Personalized PageRank (PPR) as the proximity measure and factorize the PPR matrix or its adaptation to generate embeddings. However, little previous work analyzes what information is encoded by these approaches, and how the information correlates with their superb performance in downstream tasks. In this work, we first show that state-of-the-art embedding approaches that factorize a PPR-related matrix can be unified into a closed-form framework. Then, we study whether the embeddings generated by this strategy can be inverted to better recover the graph topology information than random-walk based embeddings. To achieve this, we propose two methods for recovering graph topology via PPR-based embeddings, including the analytical method and the optimization method. Extensive experimental results demonstrate that the embeddings generated by factorizing a PPR-related matrix maintain more topological information, such as common edges and community structures, than that generated by random walks, paving a new way to systematically comprehend why PPR-based node embedding approaches outperform random walk-based alternatives in various downstream tasks. To the best of our knowledge, this is the first work that focuses on the interpretability of PPR-based node embedding approaches.
uniforum 34 (2021) Nr. 4
Creators: name: (:Unkn) Unknown
name: Justus Liebig University Giessen
Publisher: name: Universitätsbibliothek Gießen
Year: 2021
Subjects: subject: ddc:000

description: Wo jede und jeder einen Beitrag leisten kann: Das Thema Nachhaltigkeit spielt an der JLU in Forschung, Lehre und Verwaltung eine zentrale Rolle. Im Büro für Nachhaltigkeit (BfN) laufen die Fäden zusammen. Wer mutig Widerstand geleistet hat: Eine Gedenkstele für Mildred Harnack-Fish wurde am Philosophikum feierlich eingeweiht. Gemeinsames Erinnern im Rahmen der Partnerschaft Hessen Wisconsin. Wie bedrohte Seevögel geschützt werden: Wildbiologe Johannes Lang erforscht in Grönland mit Hilfe von Geologgern bedrohte Vogelarten. Eines von vielen Beispielen für Projekte zur Rettung der Artenvielfalt. Was sich hinter dem Kürzel »QuiS« verbirgt: Ob Informations- und Beratungsangebote für Studierende, Vorkurse für MINT-Fächer oder Internationalisierung des Angebots das Land fördert wichtige Lehrprojekte. Wie Statements öffentlich sichtbar werden: Studierende machen mit künstlerischen Aktionen in der Innenstadt auf ihre Botschaften aufmerksam. Eine erfolgreiche KuKo-Aktion mit Schülerinnen und Schülern.
People's revolution or state imposition?
Creators: name: Nabben, Rob
Publisher: name: RMIT University
Year: 2024

description: My aim in this study is to develop more theoretically informed praxis - and practically informed theory - about two seminal questions: "What is the good life?", and "How we are to live together?" This thesis explores community and development through the lens of a small Community Building Demonstration Project that was conducted in Melbourne's Northern suburbs between 2001 and 2005. This project, at the time, was promoted by the State Labor Government as a radical strategy that would overcome deeply entrenched social problems.

I argue that we are indeed in a predicament that does not easily lend itself to deductive-positivist methods of problem solving. Given that 'reality' can be interpreted in many ways, and knowledge itself is coloured by the interests of powerful groups, how best are we to investigate from within the frame of our own culture? Questions of the social are deeply implicated with those of the environmental, economic and cultural, thus part of the research challenge is to circumscribe a methodology that is appropriate to asking questions about how we are to work together towards the human good.

The thesis progressively contextualizes the hidden connections between the day-to-day lived experiences of those in the project and broader factors at the regional, national, and ultimately global political-economic levels. The research re-views the history of Western expansionism over the globe, firstly in the form of the colonial 'adventure', and more recently the efforts to 'develop' the Third World, in what has come to be accepted as 'modernism' and 'progress', but most typically at the cost of community. The research necessarily grapples with the contemporary litany of fashionable ideas like social capital, the Third Way, 'joined-up' government, and Participatory Rural Appraisal.

The questioning throughout the thesis of the holistic relationship between the 'personal' and the 'political' leads to various propositions about dealing with our predicament, ranging from how we may seek more respectful interpersonal relationships, to how a community-based committee might represent local interests, as well as what guiding philosophies of the state may be consistent with the goals of such 'development'.

As the nature of the predicament becomes clearer, I begin to focus on the question of the opportunities for personal agency given the seemingly overwhelming structures that surround us. The empirical study of the Community Building project reveals the contradictions and dialectics that occur when change is attempted in such a milieu. It shows the interplay of contradictions when imposition meets resistance, and what opportunities there are there to work in the space between these dialectics. It finally reveals other possibilities for understanding and acting, or for 'other discourses' that we might use to make a better future together.
Functional significance of sodium calcium exchange in arteriolar myogenic zone
Creators: name: Raina, Hema
Publisher: name: RMIT University
Year: 2024

description: To determine a possible role for NCX in myogenically active smooth muscle arterioles, studies were conducted by manipulation of extracellular Na+ levels and inhibition of the exchanger. Western blotting was performed for the identification of the NCX protein. Real-time PCR was performed to demonstrate the level of expression of mRNA, for the NCX isoforms. Antisense oligonucleotides against NCX mRNA were introduced in an isolated cremaster arteriole followed by functional studies after 24 hours. Level of expression of NCX was determined by western blotting. The data are consistent with the presence of NCX1 in the cremaster arterioles.
Promotion of scientific literacy in Bangladesh: teachers' perspectives, practices and challenges
Creators: name: Sarkar, Md. Mahbub Alam
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: In line with a current global trend, junior secondary science education in Bangladesh aims to provide science education for all students to enable them to use their science learning in everyday life. This aim is consistent with the call for scientific literacy, which argues for engaging students with science in everyday life. The study for this thesis explores how scientific literacy is promoted through junior secondary science education in Bangladesh. It looks at four areas: teachers’ perspectives of scientific literacy; the translation of their perspectives into teaching practices; the values they consider in science teaching in relation to scientific literacy, and the issues they perceive as challenging in their teaching for promoting scientific literacy. To explore these four areas, this research followed a mixed methods design where qualitative approaches, including interviews with teachers, lesson observations and focus group interviews with students, dominated the overall research process. This study reveals that whilst participating teachers held a range of perspectives of scientific literacy, including some naive perspectives, in practice they demonstrated limited capacity to translate their perspectives into their classroom teaching practices. Many of their teaching practices promoted a culture of academic science that resulted in students’ difficulty in finding connections between the science they study in school and their everyday lives. This study also reveals that teachers found difficulties in conceptualising many of the curriculum-identified values and consequently, found it difficult to find, develop and implement suitable teaching approaches to promote the values. The difficulties also included teachers encountering tension between their religious values and science values while they were teaching science in a culture with a religious tradition. These results may contribute to understanding how teaching for scientific literacy is challenged by an academically oriented curriculum, large class size, limited resources, traditional examination-oriented education and limited teacher development programmes.
sj-docx-2-srd-10.1177_23780231231225574 – Supplemental material for Changes in Americans’ Views on Who Should Provide and Pay for Assistance to Older Adults with Activity Limitations, 2012 to 2022
Creators: name: Patterson, Sarah E.
name: Reyes, Adriana M.
Publisher: name: SAGE Journals
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-2-srd-10.1177_23780231231225574 for Changes in Americans’ Views on Who Should Provide and Pay for Assistance to Older Adults with Activity Limitations, 2012 to 2022 by Sarah E. Patterson and Adriana M. Reyes in Socius
title: Nur eine Frage des Netzwerks?
Creators: name: Richter, Gerald
Year: 2009

description: Ausgangspunkt dieser Arbeit ist die Feststellung, dass in den Sportredaktionen von überregionalen Printmedien in Österreich verglichen mit anderen Ressorts nur sehr wenige Redakteurinnen beschäftigt sind. Für die vorliegende Arbeit ergibt sich die Fragestellung, wie es um Vernetzung und Karriereplanung von Sportredakteurinnen bei überregionalen Printmedien bestellt ist, und wie sie gegebenenfalls mit diskriminierenden Erlebnissen im Arbeitsalltag umgehen. Ein besonderer Schwerpunkt der Arbeit liegt dabei auf neuen Technologien zur Vernetzung im Internet, zum Beispiel die soziale Netzwerkplattform „Facebook“. Zu diesem Zweck wurden zehn Sportredakteurinnen von überregionalen österreichischen Printmedien in qualitativen Interviews über ihren Karriereverlauf, ihre Erfahrungen und den Umgang mit diskriminierenden Situationen, sowie ihre Einstellung bzw. Vorgehensweisen zur beruflichen Vernetzung befragt. Bei den Ergebnissen zeigte sich, dass praktisch alle Sportredakteurinnen in ihrer beruflichen Laufbahn schon Erfahrung mit diskriminierenden Situationen gemacht haben. Bei den Gegenstrategien zeigen sich aber einige Unterschiede, sie reichen von offener Konfrontation und der Androhung rechtlicher Schritte bis hin zu stiller Resignation. Beim Aspekt der Vernetzung der Sportredakteurinnen zur gegenseitigen Karriereförderung zeigt sich, dass bei vielen Sportredakteurinnen – zum Teil aufgrund des Konkurrenzaspekts – das Interesse an der Kontaktaufnahme und –pflege zu anderen Sportredakteurinnen nur gering ist. Auch die Nutzung der bereits erwähnten neuen Technologien ist in diesem Aspekt nur gering ausgeprägt.
Uni-Forum 17 (2004) Nr. 4
Creators: name: (:Unkn) Unknown
name: Justus Liebig University Giessen
Publisher: name: Universitätsbibliothek Gießen
Year: 2004
Subjects: subject: ddc:000

description: Wo die Reise hingeht: Mit dem Entwicklungsplan hat sich die Universität auf konkrete Perspektiven und Zielsetzungen verständigt. Das Strategiepapierliegt jetzt in Druckversion vor und ist im Internet für jedermann einsehbar. *Wie Studierende aus aller Welt in Gießen empfangen werden. Die Rundum-Betreuungdurch das Akademische Auslandsamt reicht vom Abholen am Bahnhof bis zum Behördengang oder der Praktikumsvermittlung. *Wenn Kinder nicht nur zuschauen. In Prof. Siggy´s Science Camp durften Grundschüler und Grundschülerinnen selber im Labor experimentieren. Einegelungene Aktion voll geladen und echt abstoßend *Wer bei Problemen hilft: Ob Prüfungsamt, finanzielle Nöte oderfehlende Kinderbetreuung Die Abteilung Soziale Dienste des GießenerStudentenwerks ist eine wichtige Anlaufstelle für Studierende.
Interkulturelle Kommunikation Als Kompetenz: Handlungsanleitungen Für Die Praxis Der Sozialen Arbeit
Creators: name: Baumann, Ursula
name: Huwiler, Priscilla
Publisher: name: Zenodo
Year: 2018

description: In der vorliegenden Arbeit mit dem Titel «Interkulturelle Kommunikation als Kompetenz», wird die Wichtigkeit interkultureller Kommunikation in der heutigen Zeit aufgezeigt und es werden relevante Aspekte der Sozialen Arbeit für die Umsetzung dieser Kompetenz dargestellt. Nach einer theoretischen und normativen Vertiefung in die Thematik und der Darlegung unterschiedlicher Betrachtungsweisen mittels einer Auswahl unterschiedlicher Ansätze, Techniken oder Studien folgt ein praktischer Zugang zur Umsetzung in der Praxis. Die konkrete Fragestellung lautet: Welche Handlungsgrundlagen eignen sich für eine erfolgreiche interkulturelle Kommunikation in der Praxis der Sozialen Arbeit, die Stigmatisierungen von Menschen aus anderen Kulturräumen entgegenwirken? Fachpersonen der Sozialen Arbeit sollen im Themenbereich Interkulturalität und Kommunikationsmöglichkeiten sensibilisiert werden und ein Repertoire an theorie- und praxisbezogenem Fachwissen besitzen, welches sie im professionellen Alltag einsetzen können. Der Umgang mit Differenz ist eine zentrale Aufgabe der Sozialen Arbeit. Die Menschen aus anderen Kulturräumen sollen nicht dem Stigma der hilfsbedürftigen Gruppe ausgesetzt und auf eine nationale, religiöse und ethnische Identität reduziert werden. Alleine durch spezifisches Wissen über die einzelnen Länder erhofft man sich, den Umgang und die Kommunikation mit dieser Zielgruppe zu vereinfachen. Damit die Adressatinnen und Adressaten aus anderen Kulturräumen jedoch nicht schubladisiert werden, bedarf es neben spezifischem Fachwissen anerkennende Gleichheit, welche die Gemeinsamkeiten in einer Begegnung in den Fokus nimmt.
description: + Code Diss LU: hslusa basp 2018 + Fussnote: Bachelor-Arbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Sozialpädagogik, 2018 + NL-Code: NLLUHSA201809
Additional file 3 of Mortality and its predictors among human immunodeficiency virus-infected children younger than 15 years receiving antiretroviral therapy in Ethiopia: a systematic review and meta-analysis
Creators: name: Woldegeorgis, Beshada Zerfu
name: Asgedom, Yordanos sisay
name: Gebrekidan, Amanuel Yosef
name: Kassie, Gizachew Ambaw
name: Borko, Ushula Deboch
name: Obsa, Mohammed Suleiman
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 3
Starting to feel connected: investigating interactions between adults with congenital deafblindness and disability support workers.
Creators: name: Prain, Meredith
Publisher: name: RMIT University
Year: 2024

description: This thesis reports an investigation of interactions between adults with congenital deafblindness and the disability support workers who mediate their support. These interactions are examined with a view to better understanding how social togetherness or ‘the good life’ as posited by Reinders (2002), might be better understood, evaluated and ultimately enhanced. A mixed methods design is employed. Phase one is conducted as a quantitative, observation based study in which adults with congenital deafblindness and their direct support staff are video recorded in their daily interactions, and the interactions are coded. Phase two is conducted as a qualitative interview-based study, in which staff are asked to reflect on the video interactions from phase one.

This thesis highlights the importance of using mixed methods, or at least soliciting multiple perspectives, when evaluating interactions with adults with congenital deafblindness. It demonstrates that examining interactions from only one perspective, or using one method in isolation, gives a limited and partial understanding of the situation. For example, the findings from phase one of the study showed few instances of interaction between adults with congenital deafblindness and their support staff. Similar studies in the past have interpreted such results as suggesting that the staff required further training in how to interact with their clients. However, the findings from phase two of the study, which used a different research method, revealed higher levels of interaction. Phase two also yielded additional information that helped to explain the low levels of interaction observed in the first phase. The findings from this second phase suggest a mismatch in worldviews between disability support workers and those formulating interventions to enhance interactions for adults with congenital deafblindness. For this reason, staff training to address issues raised by the first phase of the study may not deliver long-term, positive outcomes for adults with congenital deafblindness. This is because the type of intervention does not adequately address the mismatch in worldviews between the intervener and the disability support workers.

In addition to theorising about the perspectives of, and interaction between the key partners, this thesis offers some practical recommendations to progress the situation for clinicians, researchers, disability support workers, and most importantly adults with congenital deafblindness. However, much work remains to develop effective tools and methods for evaluating interactions with people with congenital deafblindness. This thesis also poses some important questions about evaluating opportunities for adults with congenital deafblindness to experience the good life within the broader quality of life construct.
uniforum 26 (2013) Nr. 5
Creators: name: (:Unkn) Unknown
name: Justus Liebig University Giessen
Publisher: name: Universitätsbibliothek Gießen
Year: 2013
Subjects: subject: ddc:000

description: Warum die JLU bundesweit im Fokus der Medien stand: Die Universität hat die Doktorarbeit von Dr. Frank-Walter Steinmeier überprüft und alle Plagiatsvorwürfezurückgewiesen. Die Pressekonferenz wurde live übertragen.Was wir von Insekten lernen können: Das Land fördert das neue LOEWE-ZentrumInsektenbiotechnologie an der JLU. Im Zentrum stehen Wirkstoffe für Medizin, Pflanzenschutz und Lebensmittelbiotechnologie.Wo junge Menschen gemeinsam lernen: Die Hermann-Hoffmann-Akademie wurdefeierlich eröffnet. Unter der Devise Lernen durch Lehren wird sie einOrt der Wissensvermittlung durch Studierende sein.Wo man Schreiben lernen kann: Die Schreibberaterinnen und Schreibberaterunterstützen Studierende bei der Anfertigung wissenschaftlicherArbeiten ein kostenloses Angebot des Schreibzentrums am ZfbK.
Death by QT: a new safety challenge
Creators: name: Raghib, Hala
Publisher: name: RMIT University
Year: 2024

description: The HERG gene encodes for the delayed rectifier K+ channel in human cardiac tissue and contributes to the repolarization phase of the ventricular action potential. Defects in its activity underlies a cardiac disorders linked to a prolongation in the QT interval known as acquired long QT syndrome. The channel has structural properties that lead to its unintentional inhibition by various classes of drugs and is a source of drug induced cardiac toxicity. To date, no assay has been set as a standard due to variability across laboratories and the use of animals providing variable results due to differences in the ion channels involved in repolarisation. This thesis focuses on the development of testing assays for HERG using animal-free methodology.

In Chapter 2, a human embryonic kidney (HEK293) cell line was cultured and transfected with the human HERG gene using animal-free methodologies. The success of the transfection was confirmed using PCR, patch clamp electrophysiology and a non-radioactive rubidium assay. Using a non-radioactive rubidium assay, drug inhibition on the transfected cell line was measured. The IC50 values obtained for a range of drugs were compared to those obtained using electrophysiological studies in the literature and there was a high correlation (r2 = 0.76).

In Chapter 3, a human neuroblastoma cell line (SH-SY5Y) was tested for its validity for testing the effect of drugs on the endogenously expressed HERG K+ channel. The drug IC50 values obtained using the Rb+ assay were well correlated (r2= 0.82) with patch clamp studies in HERG transfected HEK293 cells in the literature.

Clomipramine a clinically used antidepressant causes prolongation in the QT interval, however its mechanism of action on cardiac cells leading to this cardiotoxic effect is unclear. In this study, clomipramine was tested using HERG transfected HEK293 cells and the neuroblastoma cell line (SH-SY5Y) using a rubidium assay and whole cell patch clamp. Clomipramine inhibited HERG with an IC50 value of 8.35 µM and 2.18 µM in HERG transfected HEK293 cells and the neuroblastoma cell line (SH-SY5Y) using the rubidium assay respectively. Clomipramine inhibited HERG currents with an IC50 value of 0.50 µM using the patch clamp technique in HEK293 cells. The results indicate that the prolongation in the QT interval caused by clomipramine may involve HERG inhibition.

The HERG K+ channel is regulated by several protein kinases including protein kinase A and protein kinase B. In Chapter 5, the specific PKC activator and phorbol ester PDA was used to study HERG regulation by PKC in HERG transfected HEK293 cells. PDA caused a reduction in HERG currents in HEK293 cells. The PKC pseudo substrate inhibitor PKC [19-36] did not inhibit the effect of PDA on HERG currents. The results of the study suggest that (1) PDA could be acting directly on the channel and inhibiting its function or (2) PDA is activating other proteins which are affecting HERG currents in the HERG transfected HEK293 cells.
ENERGY CONSUMPTION REDUCTION OF COMMERCIAL BUILDINGS THROUGH THE IMPLEMENTATION OF VIRTUAL AND EXPERIMENTAL ENERGY AUDIT ANALYSIS
Creators: name: Bae, Ji Han
Publisher: name: Digital Repository at the University of Maryland
Year: 2022
Subjects: subject: Engineering
subject: Energy
subject: Environmental science
subject: Auditing
subject: Building
subject: FOS: Civil engineering
subject: Energy
subject: Modeling
subject: Screening

description: According to the U.S. Energy Information Administration (EIA), about 38 quads of the total U.S. energy consumption was consumed by residential and commercial buildings in 2017, which is about 39% of the total 2017 annual U.S. energy consumption (EIA, 2018). Additionally, the building sector is responsible for about 75% of the total U.S. electricity consumption as well as for about 70% of the projected growth in the U.S. electricity demand through 2040. It is clear that the potential for energy savings and greenhouse gas emissions reduction in existing buildings today remain largely untapped and that there is still much left to explore in respect to determining the best protocols for reducing building energy consumption on a national and even a global scale. The present work investigates the effectiveness of coupling an initial virtual energy audit screening with the conventional, hands-on, energy audit processes to more quickly and less costly obtain the potential energy savings for high energy consumption buildings. The virtual screening tool takes advantage of a customized cloud-based energy efficiency management software and the readily available building energy consumption data to identify the buildings that have the highest energy savings potential and should be given priority for performing onsite walkthroughs, detailed energy audits, and the subsequent implementation of the identified energy conservation measures (ECMs). By applying the proposed procedure to a group of buildings, the results of this study demonstrated that a combination of the software-based screening tools and a detailed experimental/onsite energy audit as necessary can effectively take advantage of the potential energy consumption and carbon footprint reduction in existing buildings today and that the low-cost/no-cost energy conservation measures alone can oftentimes result in significant savings as documented in this thesis. However, selection of the appropriate software was deemed critically important, as certain software limitations were observed to hinder the obtainment of some energy savings opportunities.
uniforum 27 (2014) Nr. 4
Creators: name: (:Unkn) Unknown
name: Justus Liebig University Giessen
Publisher: name: Universitätsbibliothek Gießen
Year: 2014
Subjects: subject: ddc:000

description: Wo der Campus der Zukunft entsteht: Im Campusbereich Philosophikum I beginnt der Bau des ersten Seminargebäudes. Dies markiert den Auftakt zur Campusentwicklung Philosophikum.Was das Rapsgenom über die Entstehung von Arten verrät: Ein Gießener Forscherteam entlockte Europas wichtigster Ölpflanze in einem internationalen Genomsequenzierungsprojekt ein großes Geheimnis.Wo es Hilfe gibt, wenn Studierende sich überfordert fühlen: Das Studiencoaching der JLU bietet kostenlose Beratung, Techniken zur Stressbewältigung, Workshops zum wissenschaftlichen Schreiben und vieles mehr.Wie unsere visuelle Wahrnehmung funktioniert: Die Psychologin Dr. Katja Dörschner-Boyaci hat den Sofja Kovalevskaja-Preis zum Aufbau einer eigenen Forschergruppe an der JLU bekommen.
Informativ? Schnell? Unkompliziert? Der Webauftritt der Bibliothek der Berlin- Brandenburgischen Akademie der Wissenschaften
Creators: name: Hetzer, Susanne
Publisher: name: Humboldt-Universität zu Berlin
Year: 2007
Subjects: subject: 020 Bibliotheks- und Informationswissenschaft

description: Die vorliegende Studie stellt die ‚elektronischen’ Bedürfnisse von Bibliotheksbenutzern in den Mittelpunkt der Betrachtung und fragt nach der Qualität der von Bibliotheken angebotenen elektronischen Dienstleistungen. Es ist möglich, mit relativ geringem Aufwand zu konkreten Aussagen über eine Website zu kommen, die die Voraussetzung für eine Verbesserung des Angebots bilden können. Am Beispiel der elektronischen Angebote der Bibliothek der Berlin-Brandenburgischen Akademie der Wissenschaften (BBAW) werden Ansprüche an Benutzungsfreundlichkeit, praktische Umsetzung und Verbesserungsmöglichkeiten aufgezeigt. Nach einem einführenden Kapitel über die Evaluation von elektronischen Dienstleistungsangeboten als Chance für Qualität und Kundenorientierung in Informationseinrichtungen, folgt eine Erörterung der Kriterien zur Evaluation von Websites und der drei dazu eingesetzten Methoden: Begutachtung, Benutzerbefragung und usability-tests. Die Ergebnisse der empirischen Untersuchung werden detaillreich dargestellt. Spezielles Augenmerk liegt auf der Qualität der angebotenen Inhalte, der Navigation und anderen Benutzungskriterien sowie der Erhebung von Benutzerbedürfnissen. Dabei gliederte sich die Betrachtung in eine funktionale Ebene (Wie benutzungsfreundlich ist die Website?) und in eine individuelle Ebene (Wie gehen die Nutzer mit der Website um?). Als praktisches Arbeitsmittel für die Bibliothek wurde eine tabellarische Übersicht von Problemen erstellt, die – nach Wichtigkeit, Lösbarkeit und zur Verfügung stehenden Ressourcen sortiert – Empfehlungen zur Lösung/Veränderung enthält.
Additional file 1 of Nebulized milk exosomes loaded with siTGF-β1 ameliorate pulmonary fibrosis by inhibiting EMT pathway and enhancing collagen permeability
Creators: name: Qiu, Chong
name: Zhao, Zhenyu
name: Xu, Chenglin
name: Yuan, Ranran
name: Ha, Yuxuan
name: Tu, Qingchao
name: Zhang, Houqian
name: Mu, Zhen
name: Xin, Quanlin
name: Tian, Yu
name: Wang, Aiping
name: Wang, Hongbo
name: Shi, Yanan
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Supplementary Material 1
Unraveling the global behavior of equation of state by explicit finite nuclei constraints
Creators: name: Venneti, Anagh
name: Gautam, Sakshi
name: Banik, Sarmistha
name: Agrawal, B. K.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We obtain posterior distribution of equations of state (EOSs) across a broad range of density by imposing explicitly the constraints from precisely measured fundamental properties of finite nuclei, in combination with the experimental data from heavy-ion collisions and the astrophysical observations of radius, tidal deformability and minimum-maximum mass of neutron stars. The acquired EOSs exhibit a distinct global behavior compared to those usually obtained by imposing the finite nuclei constraints implicitly through empirical values of selected key parameters describing symmetric nuclear matter and symmetry energy in the vicinity of the saturation density. The explicit treatment of finite nuclei constraints yields softer EOSs at low densities which eventually become stiffer to meet the maximum mass criteria. The Kullback-Leibler divergence has been used to perform a quantitative comparison of the distributions of neutron star properties resulting from the EOSs obtained from implicit and explicit finite nuclei constraints.
description: The manuscript has been accepted by Physics Letters B on May 24th 2024
uniforum 27 (2014) Nr. 5
Creators: name: (:Unkn) Unknown
name: Justus Liebig University Giessen
Publisher: name: Universitätsbibliothek Gießen
Year: 2014
Subjects: subject: ddc:000

description: Wie er die JLU zwei Jahrzehnte lang prägte: Ein Gespräch mit dem scheidenden Kanzler Dr. Michael Breitbach über Entscheidungen, Entwicklungen, Erfolgsaussichten und seine Pläne für die Zukunft.Was die gemeinsame Stärke ausmacht: Die Forschungsallianz der beiden traditionsreichen Universitäten Gießen und Marburg präsentierte sich bei einem Informationsabend im Hessischen Landtag in Wiesbaden.Wo digitale Lehrkonzepte im Fokus stehen: Fünf Hochschulen vernetzen ihre Kompetenzen im hessischen Graduiertenprogramm Elektromobilität . Zum Auftakt kam der Hessische Wissenschaftsminister Boris Rhein nach Gießen.Wie das Diskursfestival Geburtstag feiert: Zum 30-jährigen Bestehen steht das von Studierenden der Angewandten Theaterwissenschaften organisierte Festival unter dem Motto ON YOUNG PERFORMING ARTS .
sj-docx-1-smo-10.1177_20503121221139149 – Supplemental material for Bacterial uropathogens, their associated factors, and antimicrobial susceptibility pattern among adult diabetic patients in two health centers at Kombolcha town, Northeastern Ethiopia
Creators: name: Oumer, Ousman
name: Metaferia, Yeshi
name: Gebretsadik, Daniel
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, sj-docx-1-smo-10.1177_20503121221139149 for Bacterial uropathogens, their associated factors, and antimicrobial susceptibility pattern among adult diabetic patients in two health centers at Kombolcha town, Northeastern Ethiopia by Ousman Oumer, Yeshi Metaferia and Daniel Gebretsadik in SAGE Open Medicine
Zentralisierung im zweischichtigen Bibliothekssystem der Universität Hamburg
Creators: name: Doeckel, Berndt
Publisher: name: Humboldt-Universität zu Berlin
Year: 2004
Subjects: subject: 020 Bibliotheks- und Informationswissenschaft

description: Die vorliegende Arbeit thematisiert die Veränderungen im Hochschulbibliothekssystem der Universität Hamburg durch die zunehmenden Bestrebungen, Bibliotheksbestände und Personal in größeren bibliothekarischen Einheiten zusammenzufassen. Nach einer Einführung in die Probleme ein- und zweischichtiger Bibliothekssysteme werden die arbeitsteiligen Strukturen innerhalb des Bibliothekssystems der Universität Hamburg erläutert; ergänzt wird diese Darstellung durch eine Analyse der aktuellen Hochschulreformen in Hamburg und deren mögliche Auswirkungen auf die künftige Bibliothekslandschaft. Abschließend werden der Planungsprozess, das Finanzierungskonzept und die bibliothekspraktischen Probleme eines Zentralisierungsprojektes im Hochschulbibliotheksbereich am Beispiel der Zentralbibliothek Recht der Universität Hamburg skizziert.
CONNECTED ENVIRONMENT: JOINT TRAFFIC SIGNAL AND VEHICLES SPEED OPTIMIZATION FOR OPTIMUM MOBILITY AND FUEL CONSUMPTION
Creators: name: Jahangiri, Romina
Publisher: name: Digital Repository at the University of Maryland
Year: 2022
Subjects: subject: Civil engineering
subject: FOS: Civil engineering
subject: CAV
subject: connected and autonomous vehicles
subject: connected environment
subject: connected vehicles
subject: optimizing traffic signal

description: A connected environment offers an effective solution to smart cities' current concerns. The performance of existing traffic signals and speed advisory technology can be improved by cooperation between traffic signal and speed system advisory in a connected environment. This research proposes a connected intersection where the traffic light and individual vehicles' speed can be optimized simultaneously. Traffic signal timing and arrival time of the vehicles at the beginning of each cycle can be calculated to find the optimum speed, brake force, and vehicle engine power each second. The main contribution of this thesis is to consider the optimization of the traffic signal and vehicles' velocity together at the same time at different penetration rates and demand levels to optimize total travel time, stop time, delay, and fuel consumption. Few research studies have considered these simultaneously. An analysis is conducted to compare the result of this thesis with actuated and fixed-time traffic signals. The results show improvement in fuel consumption and mobility, specifically at the lower demand levels.
sj-pdf-1-vdi-10.1177_10406387221139799 – Supplemental material for A series of heterogeneous lymphoproliferative diseases with CD3 and MUM1 co-expressed in cats and dogs
Creators: name: Hughes, Kelly L.
name: Rout, Emily D.
name: Avery, Paul R.
name: Pavuk, Alana A.
name: Avery, Anne C.
name: Moore, A Russell
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, sj-pdf-1-vdi-10.1177_10406387221139799 for A series of heterogeneous lymphoproliferative diseases with CD3 and MUM1 co-expressed in cats and dogs by Kelly L. Hughes, Emily D. Rout, Paul R. Avery, Alana A. Pavuk, Anne C. Avery and A Russell Moore in Journal of Veterinary Diagnostic Investigation
uniforum 31 (2018) Nr. 5
Creators: name: (:Unkn) Unknown
name: Justus Liebig University Giessen
Publisher: name: Universitätsbibliothek Gießen
Year: 2018
Subjects: subject: ddc:000

description: Wie sich alles auf die Formel Gießen = Lunge bringen lässt: Nach dem Erfolg in der Exzellenzstrategie für das CPI wird die Lungenforschung durch ein neues Bund-Land-Institut für Lungengesundheit weiter ausgebaut.Wenn sich das Leben radikal verändert: Ein gefährdeter Wissenschaftler und Stipendiat des Scholar Rescue Fund an der JLU berichtet von seiner Haft in der Türkei und der Flucht nach Deutschland. Ein Leben in Sorge und Angst.Wie ein Schatz im Kaukasus gehoben wurde: Die erfolgreiche Kooperation des Instituts für Geographie mit einem Team der Universität Tiflis (TSU) hat Früchte getragen; der neue National Atlas of Georgia liegt vor.Wenn ein demokratisches Grundrecht hart erstritten werden muss: Unter dem Titel Bewegte Zeiten seit 1918 hat die JLU das Jubiläum 100 Jahre Frauenwahlrecht gefeiert und an die Vorkämpferinnen erinnert.
The impact of competency based progression on apprentice electricians
Creators: name: Sizer, Suzanne
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: This study examines the impact of a competency based progression approach to the training of apprentice electricians in Victoria. An expert panel report on Australian apprenticeship reform, (McDowell et al., 2011) recommended a move away from time served to competency based progression and completion. These recommendations were intended to improve apprentice completion rates, and included an increased focus on foundation skills, a mentoring arrangement, and competency based progression for the apprentice. E-Oz Energy Skills Australia is the energy sectors' industry skills council. This organisation was charged with the development and implementation of a competency based progression pilot project to implement the recommended apprenticeship reforms in the electrical trade. The research examines the pilot project from the apprentice perspective, using a small group of apprentice electricians participating in the project in Victoria. The research found there were four main factors which affected the apprentices' progression. These factors include the apprentices' motivation to complete their qualification, their entry level of literacy and numeracy skills, their maturity in taking responsibility for their own learning, which leads to an ability to progress in a blended learning environment, and the level of support or mentoring they require and are able to access. The research found the apprentices were motivated to successfully complete their qualification at their own pace, but a lack of flexibility within the Registered Training Organisations meant they were unable to progress based on their developing level of competency. Apprentices within the research criticised the blended learning resources developed for the pilot as not being up to the quality standard they expected. Furthermore, the mentoring provided by the project was generally insufficient to allow relationships to be formed; therefore the usefulness of the mentoring was limited. However the pilot project provided an excellent assessment of the apprentices' literacy and numeracy skills on entry, and was useful to assist them to achieve and maintaining the required level of these skills. Results from the research indicate that although the concept of competency based progression is based on skill rather than time, time is still an important factor in the training of apprentices. The research also identified a lack of social learning when a blended learning model is introduced, leading to a lack of peer mentoring support. This area will require further research.