cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
First observations of a dome-shaped large-scale coronal EUV wave
Creators: name: Veronig, A. M.
name: Muhr, N.
name: Kienreich, I. W.
name: Temmer, M.
name: Vrsnak, B.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present first observations of a dome-shaped large-scale EUV coronal wave, recorded by the EUVI instrument onboard STEREO-B on January 17, 2010. The main arguments that the observed structure is the wave dome (and not the CME) are: a) the spherical form and sharpness of the dome's outer edge and the erupting CME loops observed inside the dome; b) the low-coronal wave signatures above the limb perfectly connecting to the on-disk signatures of the wave; c) the lateral extent of the expanding dome which is much larger than that of the coronal dimming; d) the associated high-frequency type II burst indicating shock formation low in the corona. The velocity of the upward expansion of the wave dome ($v \sim 650$ km s$^{-1}$) is larger than that of the lateral expansion of the wave ($v \sim 280$ km s$^{-1}$), indicating that the upward dome expansion is driven all the time, and thus depends on the CME speed, whereas in the lateral direction it is freely propagating after the CME lateral expansion stops. We also examine the evolution of the perturbation characteristics: First the perturbation profile steepens and the amplitude increases. Thereafter, the amplitude decreases with r$^{-2.5 \pm 0.3}$, the width broadens, and the integral below the perturbation remains constant. Our findings are consistent with the spherical expansion and decay of a weakly shocked fast-mode MHD wave.
description: Astrophysical Journal Letters, in press
Public health and the rhetoric of personal responsibility
Creators: name: Brown, Mono M.
Publisher: name: University of British Columbia
Year: 2018

description: My dissertation examines the significance of public health messaging to perceptions of responsibility and risk. Central to this research is my view of public health campaigns as rhetorical texts—rhetoric being the art and study of persuasion—that employ discursive strategies of various kinds to achieve their aims. As rhetorical texts, public health campaigns provide a means of involving individuals in health promotion and disease prevention, which makes them a valuable resource amid growing concerns about rising healthcare costs worldwide. In four case studies, on hand hygiene, vaccination, antibiotic use, and “epidemic” obesity, I illuminate the persuasive means through which public health comes to be understood as, in the first instance, a matter of personal responsibility. Given that the rhetoric of personal responsibility places more of the onus for health on individuals than on systems, this rhetoric has long been criticized in health contexts as a form of “victim blaming.” Appeals to personal responsibility, for example, ignore the influence of context on health status. These appeals also induce cooperation among individuals by triggering feelings of anxiety, stigma, and blame. Some public health scholars celebrate these effects as essential to public health; I stress their potential to impede a society’s capacity to cope with infection. Throughout, I examine the relationship of the rhetoric of personal responsibility to neoliberalization—especially its advantages for the private sector, some of which come at the expense of public health. A political-economic theory, neoliberalism prioritizes privatization, deregulation, reduced spending on social welfare, and minimal government interference in the private sector. In each of my chapters, I critique public health’s neoliberalization by documenting consequences or conflicts of interest arising from the rhetoric of personal responsibility. One such conflict is the opportunity to profit from altered perceptions of risk and responsibility, an effect I demonstrate most emphatically in my chapters on hand hygiene and “epidemic” obesity. A rhetoric of personal responsibility also distracts from the reality that some problems—for example, antibiotic-resistant infections (ARIs) and declining vaccination rates—necessitate both societal and individual change.
Asymmetric spin-1/2 two-leg ladders
Creators: name: Aristov, D. N.
name: Brünger, C.
name: Assaad, F. F.
name: Kiselev, M. N.
name: Weichselbaum, A.
name: Capponi, S.
name: Alet, F.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We consider asymmetric spin-1/2 two-leg ladders with non-equal antiferromagnetic (AF) couplings J_|| and κJ_|| along legs (κ<= 1) and ferromagnetic rung coupling, J_\perp. This model is characterized by a gap Δin the spectrum of spin excitations. We show that in the large J_\perp limit this gap is equivalent to the Haldane gap for the AF spin-1 chain, irrespective of the asymmetry of the ladder. The behavior of the gap at small rung coupling falls in two different universality classes. The first class, which is best understood from the case of the conventional symmetric ladder at κ=1, admits a linear scaling for the spin gap Δ~ J_\perp. The second class appears for a strong asymmetry of the coupling along legs, κJ_|| << J_\perp << J_|| and is characterized by two energy scales: the exponentially small spin gap Δ~ J_\perp \exp(-J_|| / J_\perp), and the bandwidth of the low-lying excitations induced by a Suhl-Nakamura indirect exchange ~ J_\perp^2 /J_|| . We report numerical results obtained by exact diagonalization, density matrix renormalization group and quantum Monte Carlo simulations for the spin gap and various spin correlation functions. Our data indicate that the behavior of the string order parameter, characterizing the hidden AF order in Haldane phase, is different in the limiting cases of weak and strong asymmetry. On the basis of the numerical data, we propose a low-energy theory of effective spin-1 variables, pertaining to large blocks on a decimated lattice.
description: 18 pages, 11 figures
On-farm risks for resilient food and nutrition systems
Creators: name: Umberger, Wendy
Publisher: name: Unknown
Year: 2024
Subjects: Agribusiness
Crop Production/Industries
Farm Management
Food Consumption/Nutrition/Food Safety

description: Our demands on the world’s food producers continue to grow as we look to the global food system to efficiently provide growing populations with safe, nutritious and higher quality food, while also using fewer inputs and preserving vulnerable ecosystems. At the same time, rapid economic transition in many countries, increased integration of global markets and new technologies provide many opportunities for the farming sector. Smallholder farmers, who feed a significant portion of the global population, remain amongst the world’s poorest people, and they are one of the groups most vulnerable to impacts of climate change such as more extreme weather events, less predictable weather patterns, threatened water security, emerging pest and disease threats and soil and land degradation. They face complex livelihood decisions which will see many leave the sector for opportunities in urban areas, leaving increasing labour shortages in rural areas. This presentation explores options for innovation by smallholders to address these on-farm risks and the technologies, policies, and economic and social enablers needed to facilitate more resilient food and nutrition systems.
High throughput quantification of cholesterol and cholesteryl ester by electrospray ionization tandem mass spectrometry (ESI-MS/MS)
Creators: name: Liebisch, Gerhard
name: Binder, Marion
name: Schifferer, Rainer
name: Langmann, Thomas
name: Schulz, Berta
name: Schmitz, Gerd
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: Cholesterol; Cholesteryl ester; Lipid; Stable isotope labeling; Lipidomics; Sterol; Mass spectrometry; Electrospray ionization
subject: 610 Medizin

description: Analysis of free cholesterol (FC) is not well suited for electrospray ionization (ESI); however, cholesteryl ester (CE) form ammonium adducts in positive ion mode and generate a fragment ion of m/z 369 upon collision-induced fragmentation. In order to allow parallel analysis of FC and CE using ESI tandem mass spectrometry (ESI-MS/MS), we developed an acetyl chloride derivatization method to convert FC to cholesteryl acetate (CE 2:0). Derivatization conditions were chosen to provide a quantitative conversion of FC to CE 2:0 without transesterification of naturally occurring CE species. FC and CE were analyzed by direct flow injection analysis using a fragment of m/z 369 in a combination of selected reaction monitoring (SRM) and precursor ion scan for FC and CE, respectively. Quantification was achieved using deuterated D(7)-FC and CE 17:0/CE 22:0 as internal standards as well as calibration lines generated by addition of FC and naturally occurring CE species to the respective sample matrix. The developed assay showed a precision and detection limit sufficient for routine analysis. A run time of 1.3 min and automated data analysis allow high throughput analysis. Loading of human skin fibroblast and monocyte derived macrophages with stable isotope labeled FC showed a potential application of this method in metabolism studies. Together with existing mass spectrometry methodologies for lipid analysis, the present methodology will provide a useful tool for clinical and biochemical studies and expands the lipid spectrum that can be analyzed from one lipid sample on a single instrumental platform.
A Dirichlet process mixture of hidden Markov models for protein structure prediction
Creators: name: Lennox, Kristin P.
name: Dahl, David B.
name: Vannucci, Marina
name: Day, Ryan
name: Tsai, Jerry W.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: By providing new insights into the distribution of a protein's torsion angles, recent statistical models for this data have pointed the way to more efficient methods for protein structure prediction. Most current approaches have concentrated on bivariate models at a single sequence position. There is, however, considerable value in simultaneously modeling angle pairs at multiple sequence positions in a protein. One area of application for such models is in structure prediction for the highly variable loop and turn regions. Such modeling is difficult due to the fact that the number of known protein structures available to estimate these torsion angle distributions is typically small. Furthermore, the data is "sparse" in that not all proteins have angle pairs at each sequence position. We propose a new semiparametric model for the joint distributions of angle pairs at multiple sequence positions. Our model accommodates sparse data by leveraging known information about the behavior of protein secondary structure. We demonstrate our technique by predicting the torsion angles in a loop from the globin fold family. Our results show that a template-based approach can now be successfully extended to modeling the notoriously difficult loop and turn regions.
description: Published in at http://dx.doi.org/10.1214/09-AOAS296 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Multifidelity data fusion in convolutional encoder/decoder assembly networks for computational fluid dynamics
Creators: name: Dschiava
Publisher: name: University of Notre Dame
Year: 2023

description: We analyze the regression accuracy of convolutional neural networks assembled from encoders, decoders and skip connections and trained with multifidelity data. These networks benefit from a significant reduction in the number of trainable parameters with respect to an equivalent fully connected network. These architectures are also versatile with respect to the input and output dimensionality. For example, encoder-decoder, decoder-encoder or decoder-encoder-decoder architectures are well suited to learn mappings between input and outputs of any dimensionality. We demonstrate the accuracy produced by such architectures when trained on a few high-fidelity and many low-fidelity data generated from models ranging from one-dimensional functions to Poisson equation solvers in two-dimensions. We finally discuss a number of implementation choices that improve the reliability of the uncertainty estimates generated by a dropblock regularizer, and compare uncertainty estimates among low-, high- and multi-fidelity approaches.
STARD 2015 Checklist completed for the study 'Improving O-RADS Classification with ADC Mapping: Enhanced MRI-Based Characterization of Adnexal Masses
Creators: name: Aloui, Haithem
Publisher: name: Zenodo
Year: 2025
Subjects: O-RADS
MRI
adnexal mass
radiology

description: This upload contains the completed STARD 2015 Checklist for the study titled 'Improving O-RADS Classification with ADC Mapping: Enhanced MRI-Based Characterization of Adnexal Masses'. The checklist ensures compliance with reporting guidelines for diagnostic accuracy studies. It has been completed in accordance with the STARD 2015 guidelines to promote transparency and reproducibility of the research findings
The promotion of oriented axonal regrowth in the injured spinal cord by alginate-based anisotropic capillary hydrogels
Creators: name: Prang, Peter
name: Müller, Rainer
name: Eljaouhari, Ahmed
name: Heckmann, Klaus
name: Kunz, Werner
name: Weber, Thomas
name: Faber, Cornelius
name: Vroemen, Maurice
name: Bogdahn, Ulrich
name: Weidner, Norbert
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: Self-assembly; Stem cell; Nerve regeneration; Nerve tissue engineering; Hydrogel; Alginate
subject: 610 Medizin

description: Appropriate target reinnervation and functional recovery after spinal cord injury depend on longitudinally directed regrowth of transected axons. To assess the capacity to promote directed axon regeneration, alginate-based highly anisotropic capillary hydrogels (ACH) were introduced into an axon outgrowth assay in vitro and adult rat spinal cord lesions in vivo. In an entorhino-hippocampal slice culture model, alginate-based scaffolds elicit highly oriented linear axon regrowth and appropriate target neuron reinnervation. Coating of alginate-based ACH with the extracellular matrix components collagen, fibronectin, poly L-ornithine and laminin did not alter the axon regrowth response as compared to uncoated alginate-based ACH. After implantation into acute cervical spinal cord lesions in adult rats, alginate-based ACH integrate into the spinal cord parenchyma without major inflammatory responses, maintain their anisotropic structure and in parallel to findings in vitro induce directed axon regeneration across the artificial scaffold. Furthermore, adult neural progenitor cells (NPC), which have been shown to promote cell-contact-mediated axon regeneration, can be seeded into alginate-based ACH as a prerequisite to further improve the regenerative capacity of these artificial growth supportive matrices. Thus, alginate-based ACH represent a promising strategy to induce directed nerve regrowth following spinal cord injury.
Radio Continuum Observations of 47 Tucanae and Omega Centauri: Hints for Intermediate-mass Black Holes?
Creators: name: Lu, Ting-Ni
name: Kong, Albert K. H.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present results of deep radio continuum observations of two galactic globular clusters 47 Tucanae (47 Tuc) and Omega Centauri (Omega Cen) with Australia Telescope Compact Array (ATCA). No statistically significant evidence for radio emission was found from the central region for the two clusters. However, both clusters show a 2.5-sigma detection near the center that may be confirmed by future deeper radio observations. The 3-sigma upper limits of the radio observations is 20 and 40 microJy/beam for Omega Cen and 47 Tuc, respectively. By using the fundamental plane of accreting black holes which describes the relationship between radio luminosity, X-ray luminosity and black hole mass, we constrain the mass of a possible intermediate-mass black hole (IMBH) in the globualar clusters. We also compare our results with other globular clusters and discuss the existence of IMBHs in globular clusters.
description: Accepted by ApJL
Nothing but Relativity, Redux
Creators: name: Gannett, Joel W.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: Here we show how spacetime transformations consistent with the principle of relativity can be derived without an explicit assumption of the constancy of the speed of light, without gedanken experiments involving light rays, and without an assumption of differentiability, or even continuity, for the spacetime mapping. Hence, these historic results could have been derived centuries ago, even before the advent of calculus. This raises an interesting question: Could Galileo have derived Einsteinian relativity?
Additional file 4 of T7-lac promoter vectors spontaneous derepression caused by plant-derived growth media may lead to serious expression problems: a systematic evaluation
Creators: name: Krefft, Daria
name: Prusinowski, Maciej
name: Maciszka, Paulina
name: Skokowska, Aleksandra
name: Zebrowska, Joanna
name: Skowron, Piotr M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 4: Bacterial culture optical density measurements data. Optical density measurements were performed at a wavelength of 600 nm using sterile medium as a background.
Writing of Paradise: The Marian Prayers Composed by the Franciscan Tertiary Sisters of the Pütrich Regelhaus Found in Cgm 4484 and Their Historical Context
Creators: name: Donahue, Luke
Publisher: name: University of Notre Dame
Year: 2023

description: [Undergraduate Library Research Award](http://library.nd.edu/ulra/) Honorable Mention, Senior/Honors Thesis
Chemical Composition of the RS CVn-type Star 29 Draconis
Creators: name: Barisevičius, G.
name: Tautvaišienė, G.
name: Berdyugina, S.
name: Chorniy, Y.
name: Ilyin, I.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Photospheric parameters and chemical composition are determined for the single-lined chromospherically active RS CVn-type star 29 Draconis (HD 160538). From the high resolution spectra obtained on the Nordic Optical Telescope, abundances of 22 chemical elements, including the key elements such as 12C, 13C, N and O, were investigated. The differential line analysis with the MARCS model atmospheres gives Teff=4720 K, log g=2.5, Fe/H]=-0.20, [C/Fe]=-0.14, [N/Fe]=0.08, [O/Fe]=-0.04, C/N=2.40, 12C/13C=16. The low value of the 12C/13C ratio gives a hint that extra mixing processes in low-mass chromospherically active stars may start earlier than the theory of stellar evolution predicts.
Full-revivals in 2-D Quantum Walks
Creators: name: Stefanak, M.
name: Kollar, B.
name: Kiss, T.
name: Jex, I.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Recurrence of a random walk is described by the Polya number. For quantum walks, recurrence is understood as the return of the walker to the origin, rather than the full-revival of its quantum state. Localization for two dimensional quantum walks is known to exist in the sense of non-vanishing probability distribution in the asymptotic limit. We show on the example of the 2-D Grover walk that one can exploit the effect of localization to construct stationary solutions. Moreover, we find full-revivals of a quantum state with a period of two steps. We prove that there cannot be longer cycles for a four-state quantum walk. Stationary states and revivals result from interference which has no counterpart in classical random walks.
title: Bias correction of satellite data in data assimilation for numerical weather prediction
Creators: name: Francis, Devon
Publisher: name: University of Reading
Year: 2023

description: Data assimilation is a statistical technique that combines information from observations
and a mathematical model in order to make the best estimate of a state at the current time,
where the best estimate is known as the analysis. Basic data assimilation theory relies on
the assumption that the background, model and observations are unbiased. However, this
is often not the case and, if biases are left uncorrected, can cause significant systematic
errors in the analysis. When bias is only present in the observations, VarBC (Variational
Bias Correction) can correct for observation bias, and when bias is only present in the
model, WC4DVar (Weak-Constraint 4D Variational Assimilation) can correct for model
bias. However, when both observation and model biases are present, it is unknown how the
different bias correction methods interact, and the role of anchor (unbiased) observations
becomes crucial for providing a frame of reference from which the biases may be estimated.
We highlight the importance of correctly specifying the background error statistics
in VarBC to ensure that the analysis is more precise than the prior estimate. We then
demonstrate the characteristics needed in anchor observations to effectively reduce the
contamination of biases in the analysis, when one or both types of bias are corrected for.
We find that the location and timing of anchor observations is important in their ability
to reduce the contamination of bias, as well as having precise anchor observations. In
this thesis we study the mathematical theory underpinning VarBC and WC4DVar, and
demonstrate our results in a toy numerical system.
Self-trapping of a binary Bose-Einstein condensate induced by interspecies interaction
Creators: name: Adhikari, S. K.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: The problem of self-trapping of a Bose-Einstein condensate (BEC) and a binary BEC in an optical lattice (OL) and double well (DW) is studied using the mean-field Gross-Pitaevskii equation. For both DW and OL, permanent self-trapping occurs in a window of the repulsive nonlinearity $g$ of the GP equation: $g_{c1}
Different effects of adiponectin isoforms in human monocytic cells
Creators: name: Neumeier, Markus
name: Weigert, Johanna
name: Schäffler, Andreas
name: Wehrwein, Gabriele
name: Müller-Ladner, Ulf
name: Schölmerich, Jürgen
name: Wrede, Christian
name: Buechler, Christa
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: endotoxin; inflammation; adipokine; diabetes
subject: 610 Medizin

description: Adiponectin (APM) is an adipocyte-derived adipokine with immunosuppressive, antidiabetic, and antiatherosclerotic properties. Low molecular weight (LMW)- and higher molecular weight (HMW)-APM circulate in the serum and activate different signaling pathways. We were interested to see whether LMW-APM exerts different effects on monocytic cells compared with the HMW isoform. Therefore, the effects of recombinant LMW-APM produced in insect cells and the APM from higher eukaryotic cells containing HMW forms on monocytic cells were investigated with respect to apoptosis and inflammation. LMW- and HMW-APM induce apoptosis in nondifferentiated THP-1 cells, reduce macrophage scavenger receptor (MSR) A mRNA expression, and stimulate phosphorylation of adenosine monophosphate-activated protein kinase (AMPK). However, HMW-APM induces the secretion of interleukin (IL)-6 in human monocytes and THP-1 cells but does not suppress lipopolysaccharide (LPS)-induced IL-6 secretion. In contrast, LMW-APM reduces LPS-mediated IL-6 release and furthermore, stimulates IL-10 secretion, most likely by reducing the abundance of inhibitor of nuclear factor (NF)-kappaB kinase beta, leading to a diminished nuclear translocation of NF-kappaB p65. Our data indicate that the different APM isoforms do share common effects on monocytic cells but also induce isoform-specific responses. Although apoptosis, the activation of AMPK, and the reduction of MSR are mediated by all APM isoforms, only LMW-APM displays anti-inflammatory properties.
Additional file 5 of T7-lac promoter vectors spontaneous derepression caused by plant-derived growth media may lead to serious expression problems: a systematic evaluation
Creators: name: Krefft, Daria
name: Prusinowski, Maciej
name: Maciszka, Paulina
name: Skokowska, Aleksandra
name: Zebrowska, Joanna
name: Skowron, Piotr M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 5: Table summarising the basic data on the tested nutrients and price comparison. The price comparison is shown as of the highest-priced component. The prices quoted by the producers of the ingredients were used in this research may vary.
Primes in short arithmetic progressions
Creators: name: Schlage-Puchta, Jan-Christoph
Publisher: name: arXiv
Year: 2011
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11N35

description: We give a large sieve type inequality for functions supported on primes. As application we prove a conjecture by Elliott, and give bounds for short character sums over primes. The proves uses a combination of the large sieve and the Selberg sieve.
The S18Y polymorphism in the UCHL1 gene is a genetic modifier in Huntington's disease
Creators: name: Metzger, Silke
name: Bauer, Peter
name: Tomiuk, Juergen
name: Laccone, Franco
name: Didonato, Stefano
name: Gellera, Cinzia
name: Soliveri, Paola
name: Lange, Herwig W.
name: Weirich-Schwaiger, Helga
name: Wenning, Gregor K.
name: Melegh, Bela
name: Havasi, Victoria
name: Balikó, Lazlo
name: Wieczorek, Stefan
name: Arning, Larissa
name: Zaremba, Jacek
name: Sulek, Anna
name: Hoffman-Zacharska, Dorota
name: Basak, A. Nazli
name: Ersoy, Nagehan
name: Zidovska, Jana
name: Kebrdlova, Vera
name: Pandolfo, Massimo
name: Ribaï, Pascale
name: Kadasi, Ludovit
name: Kvasnicova, Marta
name: Weber, Bernhard H. F.
name: Kreuz, Friedmar
name: Dose, Matthias
name: Stuhrmann, Manfred
name: Riess, Olaf
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: Huntington's disease; Age-at-onset; Genetic modifiers; Ubiquitin carboxy-terminal hydrolase L1 (UCHL1); S18Y polymorphism
subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: An expanded polyglutamine stretch in the huntingtin protein has been identified as the pathogenetic cause of Huntington's disease (HD). Although the length of the expanded polyglutamine repeat is inversely correlated with the age-at-onset, additional genetic factors are thought to modify the variance in the disease onset. As linkage analysis suggested a modifier locus on chromosome 4p, we investigated the functional relevance of S18Y polymorphism of the ubiquitin carboxy-terminal hydrolase L1 in 946 Caucasian HD patients. In this group, the allelic variation on locus S18Y is responsible for 1.1% of the variance in the HD age-at-onset, and the rare Y allele is associated with younger-aged cases.
Path Integral Marginalization for Cosmology: Scale Dependent Galaxy Bias & Intrinsic Alignments
Creators: name: Kitching, T. D.
name: Taylor, A. N.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a path-integral likelihood formalism that extends parameterized likelihood analyses to include continuous functions. The method finds the maximum likelihood point in function-space, and marginalizes over all possible functions, under the assumption of a Gaussian-distributed function-space. We apply our method to the problem of removing unknown systematic functions in two topical problems for dark energy research : scale-dependent galaxy bias in redshift surveys; and galaxy intrinsic alignments in cosmic shear surveys. We find that scale-dependent galaxy bias will degrade information on cosmological parameters unless the fractional variance in the bias function is known to 10%. Measuring and removing intrinsic alignments from cosmic shear surveys with a flat-prior can reduce the dark energy Figure-of-Merit by 20%, however provided that the scale and redshift-dependence is known to better than 10% with a Gaussian-prior, the dark energy Figure-of-Merit can be enhanced by a factor of two with no extra assumptions.
description: 11 pages, 4 figures, submitted to MNRAS
Alterations in intestinal fatty acid metabolism in inflammatory bowel disease
Creators: name: Heimerl, Susanne
name: Moehle, Christoph
name: Zahn, Alexandra
name: Boettcher, Alfred
name: Stremmel, Wolfgang
name: Langmann, Thomas
name: Schmitz, Gerd
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: Fatty acid transport; Fatty acid synthase; Inflammatory bowel disease; Cytokine; Liver X receptor
subject: 610 Medizin

description: Inflammatory bowel disease (IBD) constitutes a severe intestinal disorder in developed countries with increasing incidence worldwide. Upcoming evidence indicates an important role of intestinal epithelial barrier function in the development of IBD. Fatty acids exert nutritional and protective effects on enterocytes, serve as activators of transcription and constitute precursors of inflammatory mediators. The aim of this study was to investigate differential regulation of genes involved in fatty acid uptake and endogenous fatty acid biosynthesis in IBD. Mucosal biopsy specimens from non-affected regions of the intestine were subjected to DNA microarray analysis. Gene array analysis revealed a variety of genes involved in fatty acid uptake and synthesis to be differentially expressed in ileum and colon of selected IBD patients. To verify these results, real-time RT-PCR was performed for selected regulated candidate genes in larger IBD sample numbers. In single biopsy analysis long chain acyl-CoA synthetase (ACSL) 1 and 4 were upregulated in IBD (P<0.05), while a significant decrease in fatty acid synthase expression was found in ileum and colon of ulcerative colitis patients (P<0.001). Expression of the transcription factor liver X receptor (LXR) which was previously shown to induce fatty acid synthase gene expression was not altered on mRNA level in IBD. However, in cell culture experiments using the human intestinal cell line LS174T induction of fatty acid synthase by the LXR ligand T0901317 was inhibited by TNFalpha. Moreover, these experiments indicated a decrease of LXR protein levels by TNFalpha treatment. These data suggest that the decrease of fatty acid synthase expression in ulcerative colitis patients could be at least partially due to a loss of LXR expression and function in the presence of pro-inflammatory cytokines. Observed alterations in expression of genes of fatty acid metabolism may contribute to the pathophysiology of ulcerative colitis.
title: Wundzentrum Dessau – Erfahrungen und Herausforderungen in der Versorgung
Creators: name: Richter, Nico
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Für eine optimale Behandlung chronischer Wunden, hat die AOK Sachsen-Anhalt zu den bereits bestehenden Angeboten neue Versorgungsverträge im Sinne einer integrierten Versorgung geschlossen.    Chronische Wunden entstehen nicht von jetzt auf gleich. Sie entwickeln sich langsam. Grunderkrankungen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 9. Mitteldeutscher Wundkongress
title: Ergebnisse des AOK Wundzentrums Berlin
Creators: name: Katz, Ullrich
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Mein Kollege, Dr. med. Frank Dörner, hat anlässlich der Sommerakademie 2018 des Hausärztebundes Berlin-Brandenburg bei der Vorstellung unseres Wundzentrums gefragt:     „Renaissance des Einfachen – oder Warum ein AOK Wundzentrum?“     Nach fast 2 Jahren Vorbereitung[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 9. Mitteldeutscher Wundkongress
Accuracy of a Large Language Model as a new tool for optometry education
Creators: name: Cardona, Genis
name: Argiles, Marc
name: Pérez-Mañá, Lluis
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: The unsupervised introduction of certain Artificial Intelligence tools in optometry education may challenge the proper acquisition of accurate clinical knowledge and skills proficiency. Large Language Models like ChatGPT (Generative Pretrained Transformer) are increasingly being used by researchers and students for work and academic assignments. The authoritative and conversationally correct language provided by these tools may mask their inherent limitations when presented with specific scientific and clinical queries. Three sets of 10 queries related to contact lenses & anterior eye, low vision and binocular vision & vision therapy were presented to ChatGPT, with instructions to provide five relevant references to support each response. Three experts and 53 undergraduate and post-graduate students graded from 0 to 10 the accuracy of the responses, and the references were evaluated for precision and relevance. Students graded from 0 to 10 the potential usefulness of ChatGPT for their academic coursework. Median scores were 7, 8 and 6 (experts) and 8, 9 and 7.5 (students) for the contact lenses & anterior eye, low vision and binocular vision & vision therapy categories, respectively. Responses to more specific queries were awarded lower scores by both experts (ρ = –0.612; P < 0.001) and students (ρ = –0.578; P = 0.001). Of 150 references, 24% were accurate and 19.3% relevant. Students graded the usefulness of ChatGPT with 7.5 (2 to 9), 7 (3 to 9) and 8.5 (3 to 10) for contact lenses & anterior eye, low vision and binocular vision & vision therapy, respectively. Careful expert appraisal of the responses and, particularly, of the references provided by ChatGPT is required in research and academic settings. As the use of these tools becomes widespread, it is essential to take proactive steps to address their limitations and ensure their responsible use.
The effects of introduced Sitka black-tailed deer (Odocoileus hemionus sitchensis) on plant and soil microbial communities on Haida Gwaii and silvicultural tools to improve western redcedar survival
Creators: name: Catomeris, Catriona
Publisher: name: University of British Columbia
Year: 2018

description: Soils support vast microbial biodiversity, which control nutrient cycling and can form symbioses with plants; however, overabundant herbivores directly and indirectly affect soils. Introduced Sitka black-tailed deer (Odocoileus hemionus sitchensis) have dramatically altered plant communities on Haida Gwaii, BC, but their effects on soils are unknown. As such, I compared soil physicochemical properties and microbial communities on deer-free and deer-inhabited islands within the archipelago. I additionally assessed the ability of deer repellents and arbuscular mycorrhizal fungal inoculum (AMF) to reduce western redcedar (Thuja plicata) browse damage and increase growth. Distinct plant and bryophyte communities on deer-free and deer-inhabited islands were influenced by Gaultheria shallon, Polystichum munitum, Rhytidiadelphus triquetrus, Hylocomium splendens, Kindbergia oregana, and Scapania bolanderi. Phospholipid fatty acid profiling revealed soils on deer-inhabited islands contained lower fungal and bacterial biomass (NS) than deer-free islands. Gram-negative bacteria were more ¹³C-depleted, likely due to the higher bryophyte cover or soil moisture, on deer-inhabited islands. Plant Root Simulator® probe-measured supply rates of NH₄⁺, Fe³⁺, and A¹³⁺ were higher (NS), while PO₄-, K⁺, and Mn²⁺ were lower (NS), on deer-inhabited islands. Soil pH was lower, while penetration resistance was higher on deer-inhabited islands. In the greenhouse, differences in chemical properties rather than AMF inoculum were likely responsible for the greater redcedar biomass when grown in soil from: a deer-inhabited island versus a deer-free island; and, a redcedar cutblock versus a cedar-free cutblock. Seedling growth did not differ between seedlings inoculated with a commercial AMF inoculum (RootGrow™) and non-inoculated seedlings in the field. A commercial deer repellent (Plantskydd®) reduced browse damage on redcedar seedlings and increased the proportion of time a seedling remained unbrowsed. Commercial inoculum did not promote seedling growth, but browse frequency was lowest on redcedar that received both deer repellent and inoculum. Browse frequency of redcedar boughs was almost a third lower in experimental plots treated with wolf urine than those treated with water. Introduced deer dramatically altered plant and soil communities, which may slow decomposition and nutrient cycling. Deer did not reduce AMF inoculum potential, but browse frequency was high, suggesting fear-inducing deer repellents are a better strategy for redcedar protection.
State Complexity of Catenation Combined with Star and Reversal
Creators: name: Cui, Bo
name: Gao, Yuan
name: Kari, Lila
name: Yu, Sheng
Publisher: name: arXiv
Year: 2010
Subjects: subject: Formal Languages and Automata Theory (cs.FL)
subject: FOS: Computer and information sciences

description: This paper is a continuation of our research work on state complexity of combined operations. Motivated by applications, we study the state complexities of two particular combined operations: catenation combined with star and catenation combined with reversal. We show that the state complexities of both of these combined operations are considerably less than the compositions of the state complexities of their individual participating operations.
description: In Proceedings DCFS 2010, arXiv:1008.1270
Long Exposure Localization in Darkness Using Consumer Cameras
Creators: name: Milford, Michael
name: Turner, Ian
name: Corke, Peter
Publisher: name: arXiv
Year: 2025
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: In this paper we evaluate performance of the SeqSLAM algorithm for passive vision-based localization in very dark environments with low-cost cameras that result in massively blurred images. We evaluate the effect of motion blur from exposure times up to 10,000 ms from a moving car, and the performance of localization in day time from routes learned at night in two different environments. Finally we perform a statistical analysis that compares the baseline performance of matching unprocessed grayscale images to using patch normalization and local neighborhood normalization - the two key SeqSLAM components. Our results and analysis show for the first time why the SeqSLAM algorithm is effective, and demonstrate the potential for cheap camera-based localization systems that function despite extreme appearance change.
Analysing the effectiveness of Just-A-Minute Optometry Clinical Pearls: a micro-learning tool in continuing optometry education
Creators: name: Prakasam, Ruby Kala
name: Yelagondula, Vijay Kumar
name: Snigdha, Snigdha
name: Hassija, Neha
name: Pathengay, Avinash
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Just-A-Minute Clinical Pearls as a microlearning concept may be beneficial in enhancing optometry and ophthalmology practice globally. Medical education often witnesses a gap in effectively translating the learnings into clinical practice, pointing to the complex and traditional teaching methods as hindrances. The present work studied the usefulness and acceptability of Just-A-Minute Optometry Clinical Pearls, a micro-learning tool, among optometrists and ophthalmologists. Just-A-Minute Optometry clinical pearls were developed by the optometry team of LV Prasad Eye Institute and shared (via email) among optometrists and ophthalmologists on a daily basis between June 2021 to May 2022. In the middle of the project, the recipients were invited to participate in an online survey. The variables studied included frequency of checking clinical pearls, simplicity of their content, grasping speed, most used subspeciality pearls, knowledge gain and retention, practice applicability, overall learning experience, and the likelihood of recommending it to a friend. Among 150 respondents, 103 (68.7%) were ophthalmologists, and 46 (30.7%) were optometrists. The majority were from private (n = 64, 42.7%) and institutional (n = 48, 32%) practices, with 102 (68.4%) having more than five years and 21 (14%) having 2–5 years of experience. About 115 (77%) respondents checked clinical pearls every day, 147 (99%) found the format easy, and 131 (88%) could grasp the content within one minute. They felt that JAM-OCP ‘always’ enhanced clinical knowledge (n = 108, 72%) and clinical applicability (n = 82, 55%) and helped in knowledge retention (n = 123, 84%). The responses to the clinical application significantly varied (Chi-square tests) among subgroups of education qualification (p < 0.001) and practice types (p < 0.03). The Just-A-Minute Optometry Clinical Pearls were beneficial to optometrists and ophthalmologists in their practices. This, as a tele-education tool, supports continuing optometry education across the globe.
title: Epithelisierung und Inflammationsreduktion unter PHMB-Macrogol-Salbe
Creators: name: Frenzel, Steffen
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Polyhexanidbiguanid (PHMB) ist als Wundspüllösung und Antiseptikum in der Behandlung von akuten, chronischen und infizierten Wunden etabliert.     Der Wirkmechanismus beruht auf folgenden Interaktionen:      Negativ geladenen Phospholipiden, dem Hauptbestandteil der Membranen Gram-negativer[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 9. Mitteldeutscher Wundkongress
title: Nierenkranke Patienten mit Wundheilungsstörungen aus internistischer Sicht
Creators: name: Marcello, Tobias
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Wundheilung und Nierenfunktion sind das Ergebnis komplexer multizellulärer Prozesse die verschiedenste Organsysteme überspannen und eine wechselseitige Beziehung aufeinander ausüben. Chronische Nierenfunktionseinschränkungen (CKD) sind klar mit dem Auftreten von Wundheilungsstörungen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 9. Mitteldeutscher Wundkongress
title: Ernährungsmedizin bei chronischen Wunden
Creators: name: Meißner, Carl
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: Wundheilungsstörung
subject: Ernährungszustand
subject: Mangelernährung
subject: Ernährungsmanagement
subject: 610 Medical sciences; Medicine

description: Ernährung sollte als Teil der gesamt-medizinischen Therapie akuter und chronischer Wunden betrachtet werden. Ein frühzeitig eingesetztes Behandlungskonzept für Patienten mit Wundheilungsproblemen kann einerseits Läsionen verhindern und andererseits eine raschere Abheilung bestehender[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 9. Mitteldeutscher Wundkongress
Human ATP-binding cassette transporter TaqMan low-density array: analysis of macrophage differentiation and foam cell formation
Creators: name: Langmann, Thomas
name: Mauerer, Richard
name: Schmitz, Gerd
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: BACKGROUND: ATP-binding cassette (ABC) transporters cause various diseases and regulate many physiologic processes, such as lipid homeostasis, iron transport, and immune mechanisms. Several ABC transporters are involved in bile acid, phospholipid, and sterol transport, and their expression is itself controlled by lipids. In addition, ABC proteins mediate drug export in tumor cells and promote the development of multidrug resistance. METHODS: We created an ABC Transporter TaqMan Low-Density Array based on an Applied Biosystems 7900HT Micro Fluidic Card. We used a 2-microL reaction well with 2 ng of sample. To evaluate this method for lipidomic research and to characterize expression patterns of ABC transporters in cells relevant for atherosclerosis research, we monitored mRNA expression in human primary monocytes, in vitro-differentiated macrophages, and cells stimulated with the liver-X-receptor and retinoid-X-receptor agonists T0901317 and 9-cis retinoic acid, mimicking sterol loading. RESULTS: The method enabled simultaneous analysis of 47 human ABC transporters and the reference gene 18S rRNA in 2 replicates of 4 samples per run. CONCLUSIONS: The new system uses only 2 ng of sample and small volumes of reagent, and the precaptured primers and probes avoided labor-intensive pipetting steps. The ABC Transporter TaqMan Low-Density Array may be a useful tool to monitor dysregulated ABC transporter mRNA profiles in human lipid disorders and cancer-related multidrug resistance and to analyze the pharmacologic and metabolic regulation of ABC transporter expression important for drug development in large-scale screening approaches.
MR colonography in inflammatory bowel disease
Creators: name: Schreyer, A. G.
name: Scheibl, K.
name: Heiss, P.
name: Feuerbach, S.
name: Seitz, J.
name: Herfarth, H.
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: Virtual colonoscopy; Colonography; MRI; Inflammatory bowel disease
subject: 610 Medizin

description: Colonography based on magnetic resonance imaging (MRI) appears to be a promising technique for polyp assessment in the colon. Several studies have evaluated this method for colonic assessment in patients with inflammatory bowel disease. We briefly review different methodologies such as dark lumen and bright lumen techniques for abdominal MRI. In addition, recently published studies concerning the sensitivity and accuracy in detecting inflammatory bowel changes in inflammatory bowel disease using MRI are discussed.
Advancing optometry internationally through competency and curriculum standards: a World Council of Optometry perspective
Creators: name: Gammoh, Yazan
name: Lewandowska, Beata I
name: Neuville, Jessica
name: Hendicott, Peter
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Advancing optometry internationally through competency and curriculum standards: a World Council of Optometry perspective
title: Quartierspiegel Wipkingen 2024
Creators: name: (:Unkn) Unknown
Publisher: name: Zentralbibliothek Zürich
Year: 2024
Subjects: subject: 314 Allgemeine Statistiken zu Europa
subject: 710 Städtebau, Raumplanung, Landschaftsgestaltung
subject: 949 Geschichte anderer Teile Europas
subject: Zürich-Wipkingen
subject: Zürich / Kreis 10
subject: Quartier
subject: Amtliche Statistik
subject: Bevölkerungsstatistik

description: Das Quartier Wipkingen ist vom Verkehr stark geprägt worden: zunächst durch die Eisenbahn, vor allem aber durch die Rosengartenstrasse – was einst als Provisorium gedacht war, zerklüftet die Gegend bis heute. Aufgewertete Zonen wie der Röschibachplatz bilden inzwischen immerhin einen wohltuenden Kontrast.