cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
An Irish Party and the British Parliament: Conor Cruise O'Brien's Parnell and His Party
Creators: name: Bull, Philip
Publisher: name: La Trobe
Year: 2022

description: This essay reassesses the importance of Conor Cruise O'Brien's Parnell and His Party, 1880–90, originally published in 1957, with particular reference to its significance in the history of the British parliament. While establishing the book's continuing relevance, both as a study of a specific political phenomenon and as a model for analysing political movements, the essay questions aspects which do not hold up in the light of subsequent research. In particular, O'Brien's account and interpretation of Parnell's behaviour in 1890–1 in the aftermath of the O'Shea divorce case is shown to be inadequate in the light of more recent research and writing.
Continental threat: How many common carp (Cyprinus carpio) are there in Australia?
Creators: name: IG Stuart
name: BG Fanson
name: JP Lyon
name: J Stocks
name: S Brooks
name: A Norris
name: L Thwaites
name: M Beitzel
name: M Hutchison
name: Q Ye
name: JD Koehn
name: Bennett, Andrew
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 The Author(s) Common carp (Cyprinus carpio) are one of the world's most destructive vertebrate pests. In Australia, they dominate many aquatic ecosystems causing a severe threat to aquatic plants, invertebrates, water quality, native fish and social amenity. The Australian Government is considering release of cyprinid herpesvirus-3 (CyHV-3) as a control measure and consequently a robust, continental-scale estimate of the carp population and biomass is essential to inform planning and risk management. Here, we pioneer a novel model-based approach to provide the first estimate of carp density (no/ha) and biomass density (kg/ha) at river reach/waterbody, basin and continental scales. We built a spatial layer of rivers and waterbodies, classified aquatic habitats and calculated the area of each throughout the range of carp in Australia. We then developed a database of fishery-independent electrofishing catch-per-unit-effort (CPUE) for habitat types, containing catch information for 574,145 carp caught at 4831 sites. Eastern Australia accounted for 96% of carp biomass and 92% of the total available wetted habitat area (16,686 km2) was occupied. To correct these data for variable detection efficiencies, we used existing electrofishing data and undertook additional field experiments to establish relationships between relative and absolute abundances. We then scaled-up site-based estimates to habitat types to generate continental estimates. The number of carp was estimated at 199.2 M (95%Crl: 106 M to 357.6 M) for an ‘average’ hydrological scenario and 357.5 M (95%Crl: 178.9 M to 685.1 M) for a ‘wet’ hydrological scenario. In eastern Australia, these numbers correspond with biomasses of 205,774 t (95%Crl: 117,532–356,482 t) (average scenario) and 368,357 t (95%Crl: 184,234–705,630 t) (wet scenario). At a continental scale the total biomass was estimated at 215,456 t for an ‘average’ hydrological scenario. Perennial lowland rivers had the highest CPUE and greatest biomass density (up to 826 kg/ha) and the modelled biomass exceeded a density-impact threshold of 80–100 kg/ha in 54% of wetlands and 97% of stream area in large lowland rivers. The continental-scale biomass estimates provide a baseline for focusing national conservation strategies to reduce carp populations below thresholds needed to restore aquatic ecosystems at a range of spatial scales.
Additional file 1 of Contribution of socio-economic and demographic factors to the trend of adequate dietary diversity intake among children (6–23 months): evidence from a cross-sectional survey in India
Creators: name: Bhati, Divya
name: Tripathy, Abhipsa
name: Mishra, Prem Shankar
name: Srivastava, Shobhit
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Additional file 1: Table S1. Pooled logistic regressionestimates for ADDI among children aged 6-23 months by their backgroundcharacteristics in India
Understanding the general practice nursing workforce in New Zealand: an overview of characteristics 2015–19
Creators: name: Hewitt, Sarah L
name: Sheridan, Nicolette F
name: Hoare, Karen
name: Mills, Jane
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems
classificationCode: 4205
subject: Nursing
classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: No description supplied
Experiences of Australian podiatrists working through the 2020 coronavirus (COVID-19) pandemic: an online survey
Creators: name: Cylie Williams
name: A Couch
name: T Haines
name: Menz, Hylton
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2021, The Author(s). Background: On the 19th of January, 2020, the Chief Medical Officer of Australia issued a statement about a novel coronavirus, or SARS-CoV-2. Since this date, there have been variable jurisdictional responses, including lockdowns, and restrictions on podiatry practice. This study aimed to describe impacts of the SARS-CoV-2 pandemic on the podiatry profession in Australia. Methods: This was a cross sectional study of Australian podiatrists using demographic data collected between 2017 and 2020, and pandemic-related question responses collected between 30th March and 31st August, 2020. Data were collected online and participants described their work settings, patient funding types, business decisions and impacts, and information sources used to guide practice decisions during this time-period. Inductive thematic analysis was used to analyse open-ended questions about their practice impact of SARS-CoV-2. Results: There were 732 survey responses, with 465 Australian podiatrists or podiatric surgeons providing responses describing pandemic impact. From these responses, 223 (49% of 453) podiatrists reported no supply issues, or having adequate supplies for the foreseeable future with personal protective equipment (PPE) or consumables to support effective infection prevention and control. The most frequent responses about employment, or hours of work, impact were reported in the various categories of “business as usual” (n = 312, 67%). Participants described most frequently using the local state and territory Department of Health websites (n = 347, 75%), and the Australian Podiatry Association (n = 334, 72%) to make decisions about their business. Overarching themes which resounded through open-ended comments was that working through the pandemic was likened to a marathon, and not a sprint. Themes were: (i) commitment to do this, (ii) it’s all in the plan, but not everything goes to plan, (iii) my support team must be part of getting through it, (iv) road blocks happen, and (v) nothing is easy, what’s next? Conclusion: Podiatrists in Australia reported variable pandemic impact on their business decisions, PPE stores, and their valued sources of information. Podiatrists also described their “marathon” journey through the pandemic to date, with quotes describing their challenges and highlights. Describing these experiences should provide key learnings for future workforce challenges, should further restrictions come into place.
A Blockchain-Based Authentication Protocol for Cooperative Vehicular Ad Hoc Network
Creators: name: AFM Suaib Akhter
name: Mohiuddin Ahmed
name: AFM Shahen Shah
name: Anwar, Adnan
name: A S M Kayes
name: Zengin, Ahmet
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. The efficiency of cooperative communication protocols to increase the reliability and range of transmission for Vehicular Ad hoc Network (VANET) is proven, but identity verification and communication security are required to be ensured. Though it is difficult to maintain strong network connections between vehicles because of there high mobility, with the help of cooperative communication, it is possible to increase the communication efficiency, minimise delay, packet loss, and Packet Dropping Rate (PDR). However, cooperating with unknown or unauthorized vehicles could result in information theft, privacy leakage, vulnerable to different security attacks, etc. In this paper, a blockchain based secure and privacy preserving authentication protocol is proposed for the Internet of Vehicles (IoV). Blockchain is utilized to store and manage the authentication information in a distributed and decentralized environment and developed on the Ethereum platform that uses a digital signature algorithm to ensure confidentiality, non-repudiation, integrity, and preserving the privacy of the IoVs. For optimized communication, transmitted services are categorized into emergency and optional services. Similarly, to optimize the performance of the authentication process, IoVs are categorized as emergency and general IoVs. The proposed cooperative protocol is validated by numerical analyses which show that the protocol successfully increases the system throughput and decreases PDR and delay. On the other hand, the authentication protocol requires minimum storage as well as generates low computational overhead that is suitable for the IoVs with limited computer resources.
Lumacaftor/ivacaftor-associated health stabilisation in adults with severe cystic fibrosis
Creators: name: King, Susannah
name: Keating, Dominic
name: Williams, Elyssa
name: Eldho Paul
name: Borg, Brigitte M
name: Finlayson, Felicity
name: Button, Brenda M
name: Wilson, John W
name: Kotsimbos, Tom
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: IntroductionLumacaftor/ivacaftor (LUM/IVA) has been shown to improve clinical outcomes in cystic fibrosis (CF) patients homozygous for Phe508del with forced expiratory volume in 1 s (FEV1) % pred >40%. We assessed the clinical utility of LUM/IVA in all eligible adult CF patients with FEV1 % pred <40% treated for at least 1 year under a single-centre managed access programme.MethodsFollowing clinical optimisation, eligible patients (n=40) with FEV1 % pred <40% were commenced on LUM/IVA and monitored for tolerance and clinical outcomes, including health service utilisation, pulmonary function, weight and body composition. 24 patients reached 1 year of treatment by the time of evaluation. Six patients discontinued due to adverse events (five for increased airways reactivity) and three underwent lung transplantation.ResultsIn comparison with the year prior to LUM/IVA commencement, significant reductions (median per year) were observed in the treatment year in the number of pulmonary exacerbations requiring hospitalisation (from 3 to 1.5; p=0.0002), hospitalisation days (from 27 to 17; p=0.0002) and intravenous antibiotic (IVAB) usage days (from 45 to 27; p=0.0007). Mean±sd change in FEV1 % pred was −2.10±1.18% per year in the year prior, with the decline reversed in the year following (+1.45±1.13% per year; p=0.035), although there was significant heterogeneity in individual responses. Mean±sd weight gain at 1 year was 2.5±4.1 kg (p=0.0007), comprising mainly fat mass (mean 2.2 kg). The proportion of patients severely underweight (body mass index <18.5 kg·m−2) decreased from 33% at baseline to 13% at 1 year (p=0.003).ConclusionThis real-world evaluation study demonstrated benefits over several clinical domains (infective exacerbations requiring hospitalisation, IVABs, pulmonary function decline and nutritional parameters) in CF patients with severe lung disease.
online_supplemental_materials – Supplemental material for The Human Alarm System for Sensational News, Online News Headlines, and Associated Generic Digital Footprints: A Uses and Gratifications Approach
Creators: name: Yu-Leung Ng
name: Xinshu Zhao
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, online_supplemental_materials for The Human Alarm System for Sensational News, Online News Headlines, and Associated Generic Digital Footprints: A Uses and Gratifications Approach by Yu-Leung Ng and Xinshu Zhao in Communication Research
INQ796361_Online_appendix_CLN – Supplemental material for Effects of the Affordable Care Act on Health Care Access and Self-Assessed Health After 3 Years
Creators: name: Courtemanche, Charles
name: Marton, James
name: Ukert, Benjamin
name: Yelowitz, Aaron
name: Zapata, Daniela
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, INQ796361_Online_appendix_CLN for Effects of the Affordable Care Act on Health Care Access and Self-Assessed Health After 3 Years by Charles Courtemanche, James Marton, Benjamin Ukert, Aaron Yelowitz and Daniela Zapata in INQUIRY: The Journal of Health Care Organization, Provision, and Financing
Additional file 1 of Antibody-free measurement of cerebrospinal fluid tau phosphorylation across the Alzheimer’s disease continuum
Creators: name: Gobom, Johan
name: Benedet, Andréa L.
name: Mattsson-Carlgren, Niklas
name: Montoliu-Gaya, Laia
name: Schultz, Nina
name: Ashton, Nicholas J.
name: Janelidze, Shorena
name: Servaes, Stijn
name: Sauer, Mathias
name: Pascoal, Tharick A.
name: Karikari, Thomas K.
name: Lantero-Rodriguez, Juan
name: Brinkmalm, Gunnar
name: Zetterberg, Henrik
name: Hansson, Oskar
name: Rosa-Neto, Pedro
name: Blennow, Kaj
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Cancer
subject: Virology

description: Additional file 1: Supplementary Table S1. Precursor and product ions used for quantification. Supplementary Table S2. Method reproducibility assessment. Supplementary Table S3. Performance of the pTau biomarkers in the biochemically characterized AD patients and controls. Supplementary Table S4. ROC curve analysis and fold-change to discriminate between amyloid positive and negative groups in TRIAD. Supplementary Table S5. ROC curve analysis and fold-change to discriminate between amyloid positive and negative groups in BioFINDER-2. Supplementary Figure S1. PRM chromatograms of the assayed tau phosphopeptides. Supplementary Figure S2. Scatter plots of phosphorylated peptide abundances in biochemically characterized AD patients and controls. Supplementary Figure S3. Correlations between the pTau PRM assay and Simoa immunoassay. Supplementary Figure S4. ROC curve analysis to discriminate between amyloid positive and negative groups in TRIAD. Supplementary Figure S5. ROC curve analysis to discriminate between amyloid positive and negative groups in BioFINDER-2. Supplementary Figure S6. Fold changes (AD versus CU-) for phospho-epitope concentrations compared with phosphorylation ratios.
Supplemental_Material – Supplemental material for Invisible middle-class Black space: Asymmetrical person and space stereotyping at the race–class nexus
Creators: name: Bonam, Courtney
name: Yantis, Caitlyn
name: Taylor, Valerie Jones
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Supplemental_Material for Invisible middle-class Black space: Asymmetrical person and space stereotyping at the race–class nexus by Courtney Bonam, Caitlyn Yantis and Valerie Jones Taylor in Group Processes & Intergroup Relations
Online_Appendix – Supplemental material for Does Democracy Enhance Health? New Empirical Evidence 1900–2012
Creators: name: Wang, Yi-Ting
name: Mechkova, Valeriya
name: Andersson, Frida
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, Online_Appendix for Does Democracy Enhance Health? New Empirical Evidence 1900–2012 by Yi-ting Wang, Valeriya Mechkova and Frida Andersson in Political Research Quarterly
Additional file 2 of Clinical characteristics and risk factors for a prolonged length of stay of patients with asymptomatic and mild COVID-19 during the wave of Omicron from Shanghai, China
Creators: name: Hu, Chen
name: Liu, Yu-Kai
name: Sun, Qi-Di
name: Du, Zheng
name: Fang, Yu-Qiang
name: Guo, Fei
name: Wang, Yu-Bo
name: He, Yong
name: Cen, Yuan
name: Zeng, Fan
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Mental Health
Virology

description: Additional file 2. The collinearity analysis of all covariates in the multivariate Logistic regression.
Supplemental_Tablesandfigures – Supplemental material for Seventeen-Year Changes in Body Mass Index, Waist Circumference, Elevated Blood Pressure, and Diabetes Phenotypes in a Cohort of Filipino Women
Creators: name: Adair, Linda S.
name: Kuzawa, Christopher
name: McDade, Thomas
name: Carba, Delia B.
name: Borja, Judith B.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, Supplemental_Tablesandfigures for Seventeen-Year Changes in Body Mass Index, Waist Circumference, Elevated Blood Pressure, and Diabetes Phenotypes in a Cohort of Filipino Women by Linda S. Adair, Christopher Kuzawa, Thomas McDade, Delia B. Carba and Judith B. Borja in Asia Pacific Journal of Public Health
Development of sham yoga poses to assess the benefits of yoga in future randomized controlled trial studies
Creators: name: R Ramamoorthi
name: D Gahreman
name: Skinner, Timothy
name: S Moss
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. Background: Although research has demonstrated the benefits of yoga to people who have been diagnosed with diabetes or at risk of diabetes, studies have not confirmed these effects can be ascribed to the specific features of the traditional postures, called asanas. Instead, the effects of asanas could be ascribed to the increase in cardiovascular activity and expenditure of energy or to the expectation of health benefits. Therefore, to establish whether asanas are beneficial, researchers need to design a control condition in which participants complete activities, called sham poses, that are equivalent to traditional asanas in physical activity and expectation of benefits. Objectives: The aim of this research was to design an appropriate suite of sham poses and to demonstrate these poses and traditional asanas are equivalent in energy expenditure, cardiovascular response, and expectations of health benefits. Methods: Twenty healthy men at medium to high risk of developing diabetes volunteered to partake in the current study. These men completed two sessions that comprised traditional asanas and two sessions that comprised sham poses—poses that utilize the same muscle groups as the asanas and were assigned fictitious Sanskrit labels. Before and after each session, heart rate, blood pressure, blood glucose levels, triglycerides levels, and oxygen saturation were measured to gauge the intensity of exercise. After each session, using a standard measure, participants also indicated the degree to which they expected the poses to improve health. Results: The degree to which the sessions affected the physiological measures (for example, pre-exercise, the heart rate for yoga and sham was 71.06 ± 4.79 and 73.88 ± 6.05, respectively, and post-exercise, the heart rate was 70.19 ± 6.16 and 73 ± 7.55, respectively) and the expectations of health improvements did not differ between the traditional asanas and the sham poses. Likewise, the degree to which each session influenced these physiological measures was negligible in both conditions. Conclusions: This study developed a series of poses that elicit similar physiological and psychological effect as traditional yoga asanas. These poses can be used in an active control group in future randomized trial studies that are designed to assess the benefits of asanas.
Additional file 1 of Stage-specific requirement for METTL3-dependent m6A modification during dental pulp stem cell differentiation
Creators: name: Luo, Haiyun
name: Liu, Wenjing
name: Zhou, Yachuan
name: Zhang, Yanli
name: Wu, Junrong
name: Wang, Ruolan
name: Shao, Longquan
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Additional Table 1： The sequence of primers used in qPCR. Additional Figure 1: KEGG enrichment analysis of m6A-tagged transcripts and the relative expression of m6A-related genes during DPSC mineralization. Additional Figure 2: H&E staining of the composites of β-TCP/HA scaffolds and DPSCs. Additional Figure 3: Volcano plots of differentially expressed genes in OM-DPSCs after METTL3 inhibition. Additional Figure 4: Immunofluorescence staining of METTL3 and NOG in DPSCs. Additional Figure 5: Immunofluorescence staining of p-Smad3 and Smad in the composites of β-TCP/HA scaffolds with METTL3-interfering DPSCs.
Supplemental_material - Vasopressin Administration Is Associated With Rising Serum Lactate Levels in Patients With Sepsis
Creators: name: Severson, Kristen A.
name: Ritter-Cox, Laura
name: Raffa, Jesse D.
name: Celi, Leo Anthony
name: Gordon, William J.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 110203 Respiratory Diseases

description: Supplemental_material for Vasopressin Administration Is Associated With Rising Serum Lactate Levels in Patients With Sepsis by Kristen A. Severson, Laura Ritter-Cox, Jesse D. Raffa, Leo Anthony Celi, and William J. Gordon in Journal of Intensive Care Medicine
IPS779184_French_and_Spanish_abstracts – Supplemental material for Education and trust: A tale of three continents
Creators: name: Güemes, Cecilia
name: Herreros, Francisco
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, IPS779184_French_and_Spanish_abstracts for Education and trust: A tale of three continents by Cecilia Güemes and Francisco Herreros in International Political Science Review
Protective impacts of household-based tuberculosis contact tracing are robust across endemic incidence levels and community contact patterns
Creators: name: J Havumaki
name: T Cohen
name: C Zhai
name: Miller, Joel
name: SD Guikema
name: MC Eisenberg
name: J Zelner
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Copyright: © 2021 Havumaki et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. There is an emerging consensus that achieving global tuberculosis control targets will require more proactive case finding approaches than are currently used in high-incidence settings. Household contact tracing (HHCT), for which households of newly diagnosed cases are actively screened for additional infected individuals is a potentially efficient approach to finding new cases of tuberculosis, however randomized trials assessing the population-level effects of such interventions in settings with sustained community transmission have shown mixed results. One potential explanation for this is that household transmission is responsible for a variable proportion of population-level tuberculosis burden between settings. For example, transmission is more likely to occur in households in settings with a lower tuberculosis burden and where individuals mix preferentially in local areas, compared with settings with higher disease burden and more dispersed mixing. To better understand the relationship between endemic incidence levels, social mixing, and the impact of HHCT, we developed a spatially explicit model of coupled household and community transmission. We found that the impact of HHCT was robust across settings of varied incidence and community contact patterns. In contrast, we found that the effects of community contact tracing interventions were sensitive to community contact patterns. Our results suggest that the protective benefits of HHCT are robust and the benefits of this intervention are likely to be maintained across epidemiological settings.
Rainfall as a trigger of ecological cascade effects in an Australian groundwater ecosystem
Creators: name: M Saccò
name: AJ Blyth
name: WF Humphreys
name: SJB Cooper
name: NE White
name: M Campbell
name: M Mousavi-Derazmahalleh
name: Q Hua
name: D Mazumder
name: Smith, Colin
name: C Griebler
name: K Grice
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2021, The Author(s). Groundwaters host vital resources playing a key role in the near future. Subterranean fauna and microbes are crucial in regulating organic cycles in environments characterized by low energy and scarce carbon availability. However, our knowledge about the functioning of groundwater ecosystems is limited, despite being increasingly exposed to anthropic impacts and climate change-related processes. In this work we apply novel biochemical and genetic techniques to investigate the ecological dynamics of an Australian calcrete under two contrasting rainfall periods (LR—low rainfall and HR—high rainfall). Our results indicate that the microbial gut community of copepods and amphipods experienced a shift in taxonomic diversity and predicted organic functional metabolic pathways during HR. The HR regime triggered a cascade effect driven by microbes (OM processors) and exploited by copepods and amphipods (primary and secondary consumers), which was finally transferred to the aquatic beetles (top predators). Our findings highlight that rainfall triggers ecological shifts towards more deterministic dynamics, revealing a complex web of interactions in seemingly simple environmental settings. Here we show how a combined isotopic-molecular approach can untangle the mechanisms shaping a calcrete community. This design will help manage and preserve one of the most vital but underrated ecosystems worldwide.
Galectins - important players of the immune response to CNS parasitic infection
Creators: name: Maruszewska-Cheruiyot, Marta
name: Stear, Michael
name: Donskow-Lysoniewska, Katarzyna
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Galectins are a family of proteins that bind β-galactosides and play key roles in a variety of cellular processes including host defense and entry of parasites into the host cells. They have been well studied in hosts but less so in parasites. As both host and parasite galectins are highly upregulated proteins following infection, galectins are an area of increasing interest and their role in immune modulation has only recently become clear. Correlation of CNS parasitic diseases with mental disorders as a result of direct or indirect interaction has been observed. Therefore, galectins produced by the parasite should be taken into consideration as potential therapeutic agents.
Additional file 6 of Experiences of mothers and significant others in accessing comprehensive healthcare in the first 1000 days of life post-conception during COVID-19 in rural Uganda
Creators: name: Nakate, Mary-Grace
name: Mackay, Sean
name: Ndirangu-Mugo, Eunice
name: Fleming, Valerie
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy
Mental Health
Computational Biology

description: Additional file 6.
Appendix_S1 – Supplemental material for Economically Efficient Hepatitis C Virus Treatment Prioritization Improves Health Outcomes
Creators: name: E. Cipriano, Lauren
name: Liu, Shan
name: Shahzada, Kaspar S.
name: Holodniy, Mark
name: D. Goldhaber-Fiebert, Jeremy
Publisher: name: SAGE Journals
Year: 2018
Subjects: Health and Community Services
Public Health and Health Services not elsewhere classified
Sociological Methodology and Research Methods

description: Supplemental material, Appendix_S1 for Economically Efficient Hepatitis C Virus Treatment Prioritization Improves Health Outcomes by Lauren E. Cipriano, Shan Liu, Kaspar S. Shahzada, Mark Holodniy and Jeremy D. Goldhaber-Fiebert in Medical Decision Making
Supplemental Material, Appendix_A_-_Newest_Vital_Sign_(1) - Clinical Trial Results Summary for Laypersons: A User Testing Study
Creators: name: D. K. Raynor
name: L. Myers
name: K. Blackwell
name: B. Kress
name: A. Dubost
name: A. Joos
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental Material, Appendix_A_-_Newest_Vital_Sign_(1) for Clinical Trial Results Summary for Laypersons: A User Testing Study by D. K. Raynor, L. Myers, K. Blackwell, B. Kress, A. Dubost, and A. Joos in Therapeutic Innovation & Regulatory Science
DS_10.1177_0022034518799080 – Supplemental material for Predicting Caries in Medical Settings: Risk Factors in Diverse Infant Groups
Creators: name: M. Fontana
name: G.J. Eckert
name: M.A. Keels
name: R. Jackson
name: B.P. Katz
name: A.R. Kemper
name: B.T. Levy
name: S.M. Levy
name: E. Yanca
name: S. Kelly
name: J.M. Daly
name: B. Patterson
name: P. McKnight
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, DS_10.1177_0022034518799080 for Predicting Caries in Medical Settings: Risk Factors in Diverse Infant Groups by M. Fontana, G.J. Eckert, M.A. Keels, R. Jackson, B.P. Katz, A.R. Kemper, B.T. Levy, S.M. Levy, E. Yanca, S. Kelly, J.M. Daly, B. Patterson and P. McKnight in Journal of Dental Research
Online_Appendices_rev – Supplemental material for Love or Comprehension? Exploring Strategies for Children’s Prosocial Media Effects
Creators: name: Marie-Louise Mares
name: Bonus, James Alex
name: Peebles, Alanna
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, Online_Appendices_rev for Love or Comprehension? Exploring Strategies for Children’s Prosocial Media Effects by Marie-Louise Mares, James Alex Bonus and Alanna Peebles in Communication Research
Supplemental material for Evaluation of decentralization and commercialization in the urban water sector of Yemen
Creators: name: Al-Saidi, Mohammad
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 160509 Public Administration

description: Supplemental material for Evaluation of decentralization and commercialization in the urban water sector of Yemen by Mohammad Al-Saidi in International Review of Administrative Sciences
appendix 2 - Supplemental material for Assessment of Attractants for Neotropical Mammals
Creators: name: Duarte, Herbert De Oliveira Barbosa
name: Norris, Darren
name: Michalski, Fernanda
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Geography
subject: 120505 Regional Analysis and Development
subject: FOS: Social and economic geography

description: Supplemental material, appendix 2 for Assessment of Attractants for Neotropical Mammals by Herbert de Oliveira Barbosa Duarte, Darren Norris and Fernanda Michalski in Tropical Conservation Science
Additional file 3 of Socioeconomic position, built environment and physical activity among children and adolescents: a systematic review of mediating and moderating effects
Creators: name: Andersen, Oddbjørn Klomsten
name: Gebremariam, Mekdes Kebede
name: Kolle, Elin
name: Tarp, Jakob
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3.
Overcoming roadblocks in computational roadmaps to the future for safe nanotechnology
Creators: name: Karakus, Ceyda Oksel
name: Winkler, David
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: This is the Accepted Manuscript version of an article accepted for publication in Nano Futures. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at https://doi.org/10.1088/2399-1984/abe560
 This Accepted Manuscript is available for reuse under a CC BY-NC-ND licence after the 12 month embargo period provided that all the terms of the licence are adhered to.
Discovery of synergistic material-topography combinations to achieve immunomodulatory osteoinductive biomaterials using a novel in vitro screening method: The ChemoTopoChip
Creators: name: Burroughs, Laurence
name: M Amer
name: Matthews Vassey
name: Koch, Brita
name: Grazziela Figueredo
name: Blessing Mukonoweshuro
name: Mikulskis, Paulius
name: Vasilevich, Aleksei
name: IL Dryden
name: Winkler, David
name: Ghaemmaghami, Amer
name: Rose, Felicity
name: De Boer, Jan
name: Alexander, Morgan
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: No description supplied
Outcomes from international field trials with Male Aedes Sound Traps: Frequency-dependent effectiveness in capturing target species in relation to bycatch abundance
Creators: name: Staunton, Kyran M
name: Leiva, Donovan
name: Cruz, Alvaro
name: Joelyn Goi
name: Arisqueta, Carlos
name: Jianyi Liu
name: Desnoyer, Mark
name: Howell, Paul
name: Espinosa, Francia
name: Azael Che Mendoza
name: Karl, Stephan
name: Crawford, Jacob E
name: Xiang, Wei
name: Manrique-Saide, Pablo
name: Achee, Nicole L
name: Grieco, John P
name: Ritchie, Scott A
name: Burkot, Thomas R
name: Snoad, Nigel
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Aedes aegypti and Aedes albopictus vector dengue, chikungunya and Zika viruses. With both species expanding their global distributions at alarming rates, developing effective surveillance equipment is a continuing priority for public health researchers. Sound traps have been shown, in limited testing, to be highly species-specific when emitting a frequency corresponding to a female mosquito wingbeat. Determining male mosquito capture rates in sound traps based on lure frequencies in endemic settings is the next step for informed deployment of these surveillance tools. We field-evaluated Male Aedes Sound Traps (MASTs) set to either 450 Hz, 500 Hz, 550 Hz or 600 Hz for sampling Aedes aegypti and/or Aedes albopictus and compared catch rates to BG-Sentinel traps within Pacific (Madang, Papua New Guinea) and Latin American (Molas, Mexico and Orange Walk Town, Belize) locations. MASTs set to 450–550 Hz consistently caught male Ae. aegypti at rates comparable to BG-Sentinel traps in all locations. A peak in male Ae. albopictus captures in MASTs set at 550 Hz was observed, with the lowest mean abundance recorded in MASTs set to 450 Hz. While significantly higher abundances of male Culex were sampled in MASTs emitting lower relative frequencies in Molas, overall male Culex were captured in significantly lower abundances in the MASTs, relative to BG-Sentinel traps within all locations. Finally, significant differences in rates at which male Aedes and Culex were positively detected in trap-types per weekly collections were broadly consistent with trends in abundance data per trap-type. MASTs at 550 Hz effectively captured both male Ae. aegypti and Ae. albopictus while greatly reducing bycatch, especially male Culex, in locations where dengue transmission has occurred. This high species-specificity of the MAST not only reduces staff-time required to sort samples, but can also be exploited to develop an accurate smart-trap system—both outcomes potentially reducing public health program expenses.
Evaluating Stream Restoration: Impacts of Sedimentation and Restoration Techniques
Creators: name: Allman, Briana
name: Barnett, Jackson
name: Pleasant, Christopher
Publisher: name: QUBES Educational Resources
Year: 2025

description: Stream ecosystems rely on habitat heterogeneity, riparian-stream interactions, and hydraulic retention to enhance resilience and restoration success. This lesson equips students with the tools to analyze restoration outcomes using R, focusing on one-way ANOVA to assess ecological differences among treatment types: reference (Ref), impacted (Imp), and two restoration approaches (Res-b and Res-w).

Students begin by reviewing a foundational research paper before engaging in a structured coding assignment. They preprocess ecological data, reorder treatment groups, and implement ANOVA tests to examine statistically significant differences. Diagnostic plots are used to check model assumptions, followed by Tukey’s HSD to identify treatment effects. Summary statistics are calculated, and professional-quality plots are created using ggplot2, integrating error bars and grouping labels to highlight key trends. The lesson emphasizes the distinction between statistical significance—determining numerical differences—and biological significance, ensuring meaningful ecological interpretation.

Instructor support materials, including teaching notes, discussion prompts, and implementation strategies, facilitate adaptable lesson delivery across various educational settings. By integrating ecological theory with statistical analysis, the lesson strengthens students’ ability to critically assess restoration techniques and interpret statistical outcomes in a biological context, preparing them for research and applied environmental work.
Crime, Punishment, and Death: Reading Finitude and the Self in David Malouf's 'The Conversations at Curlow Creek'
Creators: name: Chinmaya Lal Thakur
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: The present paper reads David Malouf’s 1996 novel The Conversations at Curlow Creek as portraying a vivid and realistic picture of events relating to crime and punishment in colonial Australia in the early nineteenth century. The depiction of death penalty accorded to the bushranger Daniel Carney under the supervision of the Irish sheriff Michael Adair in New South Wales thus resonates with numerous historical accounts of incidents that actually happened. The novel, however, does more than only provide accurate historical representation as it also presents Adair as having undergone a rather dramatic transformation in the process of conversing with Carney before the latter’s execution. The paper, drawing on the views of the German philosopher Martin Heidegger, argues that a realization of inevitable mortality, of facing certain death characterizes this change in Adair’s nature and worldview. It concludes by suggesting that Adair’s acceptance of his finitude intimates of a way of being in the world that not only subverts procedures of administering punishment to convicts in colonial Australia but also indicates the limits of polarized identity politics that shapes the country in the present times.
Investigating Adolescent Discourse in Critical Thinking: Monologic Responses to Stories Containing a Moral Dilemma
Creators: name: Wallis, Adele K
name: Westerveld, Marleen F
name: Waters, Allison M
name: Snow, Pamela
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Purpose The adolescent developmental task of establishing autonomy from parents is supported through various aspects of executive functioning, including critical thinking. Our aim was to investigate younger and older adolescent language performance in form, content, and use in response to a moral dilemma task. Method Forty-four typically developing adolescents completed a language sampling task, responding to stories that contained a moral dilemma for one of the characters. Two age groups participated: younger adolescents ( n = 24, 12;2–13;11 [years;months]) and older adolescents ( n = 20, 16;1–17;11). Participants produced a monologue in response to an open-ended question prompt. Responses were transcribed and analyzed for discourse production on measures of form (verbal productivity and syntactic complexity) and content (semantic diversity and word percentages in three semantic domains: affective, social, and cognitive). Language use was evaluated using a coding system based on Bloom's revised taxonomy of thinking. Results There were no significant group differences in performance on measures of syntactic complexity and semantic diversity. Significant differences were found in adolescents' language using Bloom's revised taxonomy. The younger adolescents demonstrated a significantly higher proportion of utterances at Level 1 (remembering and understanding) compared to older adolescents, while the older age group produced a higher proportion at Level 3 (evaluating and creating). Conclusions The moral dilemma task was effective in demonstrating the growth of adolescent language skills in use of language for critical thinking. The results highlight the clinical utility of the moral dilemma task in engaging adolescents in discourse involving critical thinking, whereas the associated coding scheme, based on Bloom's revised taxonomy of thinking, may differentiate levels of critical thinking and provide direction for intervention.
A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy
Creators: name: J Li
name: A Wuethrich
name: AAI Sina
name: HH Cheng
name: Y Wang
name: Behren, Andreas
name: PN Mainwaring
name: M Trau
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: The introduction of immune checkpoint inhibitors has demonstrated significant improvements in survival for subsets of cancer patients. However, they carry significant and sometimes life-threatening toxicities. Prompt prediction and monitoring of immune toxicities have the potential to maximise the benefits of immune checkpoint therapy. Herein, we develop a digital nanopillar SERS platform that achieves real-time single cytokine counting and enables dynamic tracking of immune toxicities in cancer patients receiving immune checkpoint inhibitor treatment - broader applications are anticipated in other disease indications. By analysing four prospective cytokine biomarkers that initiate inflammatory responses, the digital nanopillar SERS assay achieves both highly specific and highly sensitive cytokine detection down to attomolar level. Significantly, we report the capability of the assay to longitudinally monitor 10 melanoma patients during immune inhibitor blockade treatment. Here, we show that elevated cytokine concentrations predict for higher risk of developing severe immune toxicities in our pilot cohort of patients.
Additional file 2 of Clustering Deviation Index (CDI): a robust and accurate internal measure for evaluating scRNA-seq data clustering
Creators: name: Fang, Jiyuan
name: Chan, Cliburn
name: Owzar, Kouros
name: Wang, Liuyang
name: Qin, Diyuan
name: Li, Qi-Jing
name: Xie, Jichun
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Hematology
subject: Plant Biology

description: Additional file 2. Review history.
Computationally repurposed drugs and natural products against RNA dependent RNA polymerase as potential COVID-19 therapies
Creators: name: Piplani, Sakshi
name: Singh, Puneet
name: Winkler, David
name: Petrovsky, Nikolai
Publisher: name: La Trobe
Year: 2021
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences
classificationCode: 3404
subject: Medicinal and biomolecular chemistry

description: Repurposing of existing drugs and drug candidates is an ideal approach to identify new potential therapies for SARS-CoV-2 that can be tested without delay in human trials of infected patients. Here we applied a virtual screening approach using Autodock Vina and molecular dynamics simulation in tandem to calculate binding energies for repurposed drugs against the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp). We thereby identified 80 promising compounds with potential activity against SARS-Cov2, consisting of a mixture of antiviral drugs, natural products and drugs with diverse modes of action. A substantial proportion of the top 80 compounds identified in this study had been shown by others to have SARS-CoV-2 antiviral effects in vitro or in vivo, thereby validating our approach. Amongst our top hits not previously reported to have SARS-CoV-2 activity, were eribulin, a macrocyclic ketone analogue of the marine compound halichondrin B and an anticancer drug, the AXL receptor tyrosine kinase inhibitor bemcentinib. Our top hits from our RdRp drug screen may not only have utility in treating COVID-19 but may provide a useful starting point for therapeutics against other coronaviruses. Hence, our modelling approach successfully identified multiple drugs with potential activity against SARS-CoV-2 RdRp.
Supplemental_data – Supplemental material for Observations on Holocene subfossil tree remains from high-elevation sites in the Italian Alps
Creators: name: Bernabei, Mauro
name: Bontadi, Jarno
name: Nicolussi, Kurt
Publisher: name: SAGE Journals
Year: 2018
Subjects: Geography
History

description: Supplemental material, Supplemental_data for Observations on Holocene subfossil tree remains from high-elevation sites in the Italian Alps by Mauro Bernabei, Jarno Bontadi and Kurt Nicolussi in The Holocene
Additional file 3 of Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context
Creators: name: Quinn-Scoggins, Harriet D.
name: Murray, Rachael L.
name: Quaife, Samantha L.
name: Smith, Pamela
name: Brain, Kate E.
name: Callister, Matthew E. J.
name: Baldwin, David R.
name: Britton, John
name: Crosbie, Philip A. J.
name: Thorley, Rebecca
name: McCutchan, Grace M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 3. GRIPP2 Short Checklist. This file shows a completed GRIPP2 short reporting checklist.