cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Learning and Unlearning of Fabricated Knowledge in Language Models
Creators: name: Sun, Chen
name: Miller, Nolan Andrew
name: Zhmoginov, Andrey
name: Vladymyrov, Max
name: Sandler, Mark
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computation and Language (cs.CL)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: What happens when a new piece of knowledge is introduced into the training data and how long does it last while a large language model (LM) continues to train? We investigate this question by injecting facts into LMs from a new probing dataset, "Outlandish", which is designed to permit the testing of a spectrum of different fact types. When studying how robust these memories are, there appears to be a sweet spot in the spectrum of fact novelty between consistency with world knowledge and total randomness, where the injected memory is the most enduring. Specifically we show that facts that conflict with common knowledge are remembered for tens of thousands of training steps, while prompts not conflicting with common knowledge (mundane), as well as scrambled prompts (randomly jumbled) are both forgotten much more rapidly. Further, knowledge-conflicting facts can "prime'' how the language model hallucinates on logically unrelated prompts, showing their propensity for non-target generalization, while both mundane and randomly jumbled facts prime significantly less. Finally, we show that impacts of knowledge-conflicting facts in LMs, though they can be long lasting, can be largely erased by novel application of multi-step sparse updates, even while the training ability of the model is preserved. As such, this very simple procedure has direct implications for mitigating the effects of data poisoning in training.
Supporting Notes
Creators: name: Halls, Justin
Publisher: name: figshare
Year: 2017
Subjects: subject: 60201 Behavioural Ecology
subject: FOS: Biological sciences

description: MS Word document with general notes, images and details of how to configure Audacity as well as a spreadsheet with a summary of the call parameters for British Species as given in Russ.
Four-terminal graphene-superconductor thermal switch controlled by the superconducting phase difference
Creators: name: Liu, Peng-Yi
name: Mao, Yue
name: Sun, Qing-Feng
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: We propose a superconducting phase-controlled thermal switch based on a four-terminal graphene-superconductor system. By the coupling of two superconducting leads on a zigzag graphene nanoribbon, both the normal-transmission coefficient and the crossed-Andreev-reflection coefficient, which dominate the thermal conductivity of electrons in the graphene nanoribbon, can be well controlled simultaneously by the phase difference of the superconducting leads. As a result, the thermal conductivity of electrons in the graphene nanoribbon can be tuned and a thermal switching effect appears. Using the nonequilibrium Green's function method, we verify this thermal switching effect numerically. At ambient temperatures less than about one tenth of the superconducting transition temperature, the thermal switching ratio can exceed 2000. The performance of the thermal switch can be regulated by the ambient temperature, and doping or gating can slightly increase the thermal switching ratio. The use of narrower graphene nanoribbons and wider superconducting leads facilitates the obtaining of larger thermal switching ratios. This switching effect of electronic thermal conductance in graphene is expected to be experimentally realized and applied.
description: 9 pages, 5 figures
MOESM1 of Genetic diversity of three surface protein genes in Plasmodium malariae from three Asian countries
Creators: name: Srisutham, Suttipat
name: Saralamba, Naowarat
name: Sriprawat, Kanlaya
name: Mayxay, Mayfong
name: Smithuis, Frank
name: Nosten, Francois
name: Pukrittayakamee, Sasithon
name: Day, Nicholas
name: Dondorp, Arjen
name: Imwong, Mallika
Publisher: name: figshare
Year: 2018
Subjects: subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Additional file 1. Specific primers and PCR conditions for isolation of 3 surface protein genes.
Dissipation and dephasing in quantum Hall interferometers
Creators: name: Liu, Peng-Yi
name: Sun, Qing-Feng
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In recent years, counter-intuitive results have shown that the quantum Hall edge states with topological protection can be dissipative. In this paper, we point out that the non-equilibrium nature of edge states in quantum Hall interferometers leads to inevitable dissipation. We consider a graphene interferometer operating in the integer quantum Hall regime and simulate the inelastic scattering that causes both dissipation and dephasing in the interferometer using non-equilibrium Green's function and virtual leads. We describe the dissipation process with the numerical results of the spatial distribution of heat generation and the evolution of electron energy distribution. In addition, with the enhancement of dephasing, a competition between Aharonov-Bohm interference and topologically protected quantized Hall plateaus is observed in the oscillations and fluctuations of the Hall resistances. At a suitable dephasing strength, quantum Hall plateaus can be promoted by dephasing. Our results not only give clues for the design of dissipation-free devices but also provide a platform for studying the non-equilibrium relaxation and the dissipation mechanism of topological states.
description: 14 pages, 7 figures
A Study on Efficiency of Factories Act 1948, in Selected Manufacturing Companies in Coimbatore
Creators: name: Neetu P M, Niraimathi.E
Publisher: name: Zenodo
Year: 2025

description: The Factories Act, 1948, is a key regulatory framework in India aimed at ensuring worker safety, health,and welfare within industrial environments. This article investigates the extent of compliance with the Actamong selected manufacturing companies in Coimbatore, a major industrial hub. Employing a mixedmethods approach, the study aims to identify compliance levels, challenges faced by businesses, and theAct's impact on worker productivity and job satisfaction. The findings suggest that while larger companiestend to comply more effectively, smaller enterprises face significant barriers. Recommendations forimproving compliance and worker well-being are also presented.
Additional file 1: of Mortality impact of an increased blood glucose cut-off level for hypoglycaemia treatment in severely sick children in Malawi (SugarFACT trial): study protocol for a randomised controlled trial
Creators: name: Baker, Tim
name: Dube, Queen
name: Langton, Josephine
name: Hildenwall, Helena
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Developmental Biology
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences

description: SPIRIT check list. (DOCX 62 kb)
Attenuated Clostridium novyias Cancer antagonist
Creators: name: Macherki M., E.
Publisher: name: figshare
Year: 2017
Subjects: subject: 60501 Bacteriology
subject: FOS: Biological sciences
subject: Cancer

description: A new study by Roberts and colleagues has shown that intratumoural injection of an attenuatedversion of Clostridium novyi bacteria can reduce tumour volume in several preclinical animal modelsas well as in one human.
Additional file 1 of Effect of cyclophospamide, doxorubicin, vincristine and prednisone/prednisolone (CHOP) chemotherapy regimens on left ventricular systolic function and cardiac structural abnormalities in non-Hodgkin lymphoma patients
Creators: name: Septianda, Imanita
name: Alsagaff, Mochamad Yusuf
name: Pikir, Budi Susetyo
name: Ashariati, Ami
name: Fuadi, Muhamad Robiul
name: Zahra, Fatimah
Publisher: name: figshare
Year: 2025
Subjects: Medicine
Pharmacology
Developmental Biology
Cancer
Science Policy
Hematology

description: Supplementary Material 1.
Immobilisation de déchets magnésiens dans un matériau alcali-activé : étude expérimentale et modélisation
Creators: name: RIFAI, Farah
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: L’immobilisation d’alliages de magnésium et de graphite, provenant de l’exploitation de la première génération de réacteurs nucléaires en France, dans un mortier de laitier activé est actuellement étudiée. L’ensemble formé peut être sujet à un gradient de température (réactions d’hydratation du liant), à la restriction des déformations différées du liant et à la corrosion du métal. L’évaluation des risques d’endommagement est donc importante. Pour cela, une approche numérique basée sur des données expérimentales est en cours de développement. L’étude couvre le comportement thermo-chemomécanique du mortier (hydratation, déformations différées et propriétés mécaniques) et la corrosion du métal enrobé. Les résultats montrent que le comportement mécanique du mortier est bien décrit par le modèle basé sur le temps équivalent. Bien que le retrait endogène important du matériau puisse engendrer des contraintes internes, sa grande capacité de fluage aide à la relaxation et évite l’endommagement. La vitesse de corrosion du magnésium dans le mortier est faible. La nature des produits de corrosion et leurs propriétés mécaniques sont identifiées par des observations MEB/EDS et nanoindentation.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
MOESM2 of Genetic diversity of three surface protein genes in Plasmodium malariae from three Asian countries
Creators: name: Srisutham, Suttipat
name: Saralamba, Naowarat
name: Sriprawat, Kanlaya
name: Mayxay, Mayfong
name: Smithuis, Frank
name: Nosten, Francois
name: Pukrittayakamee, Sasithon
name: Day, Nicholas
name: Dondorp, Arjen
name: Imwong, Mallika
Publisher: name: figshare
Year: 2018
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. Domain prediction of P. malariae TRAP, AMA1, and P48/45 using InterPro.
Anomalous photon-assisted tunneling in periodically driven Majorana nanowires and BCS Charge Measurement
Creators: name: Zhuang, Yuchen
name: Sun, Qing-Feng
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The photon-assisted tunneling of Majorana bound states in a Majorana nanowire driven by the periodic field is studied both theoretically and numerically. We find that Majorana bound states exhibit an anomalous photon-assisted tunneling signal which is different from an ordinary fermionic state : the height of photonic sidebands is related to the degree of Majorana nonlocality. Moreover, we show that the Bardeen-Cooper-Schrieffer (BCS) charge and spin components of subgap states can be well revealed by the local conductance. Our work illuminates the effect of driving field on Majorana bound states and provides a systematic scheme to directly measure BCS information of overlapping Majorana bound states
description: 14 pages, 8 figures
Durabilité d'un BAP à base des agrégats recyclés et de pouzzolane naturelle dans des milieux agressifs
Creators: name: OMRANE, Mohammed
name: KENAI, Said
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: Les bétons auto plaçant sont découverts depuis les années 1980 au Japon. Ces bétons se caractérisent par, une grande fluidité, une homogénéité et une mise en place correcte par gravitation et sans vibration. Ces bétons se développent rapidement et semblent être amenés à remplacer, à terme, les bétons vibrés classiques dans de nombreuses applications. La performance de ces bétons à l’état frais et durci est bien étudiée mais leur durabilité en milieux agressifs reste à élucider. Afin d’améliorer la durabilité de ces BAP, on évalue l’influence de l’ajout des matériaux locaux tel que la pouzzolane naturelle de Béni-Saf et l’influence de l'utilisation des agrégats recyclés sur les caractéristiques du BAP vis-à-vis des milieux agressifs (acides). Les résultats obtenus montrent que : La perte en poids des bétons auto plaçant à base des agrégats recyclés (BAPR) immergés dans la solution d’acide de concentration 5% est inférieure à ceux des bétons auto plaçant à base des agrégats naturels (BAPN), cas de l’acide sulfurique H2SO4, ceci indique que l'utilisation de 50% des agrégats recycles avec 50% des agrégats naturels pour former un (BAPR) offre une bonne protection contre l’attaque des (BAPR) par l’acide sulfurique H2SO4.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
Impact of synthesis method on the structure and function of high entropy oxides
Creators: name: González-Rivas, Mario U.
name: Aamlid, Solveig S.
name: Rutherford, Megan R.
name: Freese, Jessica
name: Sutarto, Ronny
name: Chen, Ning
name: Villalobos-Portillo, Edgar E.
name: Castillo-Michel, Hiram
name: Kim, Minu
name: Takagi, Hidenori
name: Green, Robert J.
name: Hallas, Alannah M.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: The term sample dependence describes the troublesome tendency of nominally equivalent samples to exhibit different physical properties. High entropy oxides (HEOs) are a class of materials where sample dependence has the potential to be particularly profound due to their inherent chemical complexity. In this work, we prepare a spinel HEO of identical nominal composition by five distinct methods, spanning a range of thermodynamic and kinetic conditions: solid state, high pressure, hydrothermal, molten salt, and combustion syntheses. By structurally characterizing these five samples across all length scales with a variety of x-ray methods, we find that while the average structure is unaltered, the samples vary significantly in their local structures and their microstructures. The most profound differences are observed at intermediate length scales, both in terms of crystallite morphology and cation homogeneity. As revealed by x-ray fluorescence microscopy ideal cation homogeneity is achieved only in the case of combustion synthesis. These structural differences in turn significantly alter the observed functional properties, which we demonstrate via characterization of their magnetic response. While ferrimagnetic order is retained across all five samples, the sharpness of the transition, the size of the saturated moment, and the coercivity all show marked variations with synthesis method. We conclude that the chemical flexibility inherent to HEOs is complemented by strong synthesis method dependence, providing another axis along which to optimize these materials for a wide range of applications.
description: 14 pages, 5 figures
Additional file 2: of Mortality impact of an increased blood glucose cut-off level for hypoglycaemia treatment in severely sick children in Malawi (SugarFACT trial): study protocol for a randomised controlled trial
Creators: name: Baker, Tim
name: Dube, Queen
name: Langton, Josephine
name: Hildenwall, Helena
Publisher: name: figshare
Year: 2018
Subjects: subject: Developmental Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Study definitions of emergency signs. (DOCX 18 kb)
Variabilités des performances de bétons de chanvre en fonction des caractéristiques de la chènevotte utilisée
Creators: name: NIYIGENA, César
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: Le Béton de Chanvre (BC) est considéré comme un éco-matériau en raison de ses atouts environnementaux. Il est composé essentiellement de la chènevotte, du liant et de l’eau. La qualité de la chènevotte est sensible au terrain de production et au parcours de transformation, d’où sa variabilité pouvant freiner le développement du BC. Notre étude vise à évaluer scientifiquement, l’impact de cette variabilité sur les performances du BC. Elle passe par deux étapes principales : (1) la prédiction de l’impact de la chènevotte sur le BC, (2) caractérisation du BC. L’analyse multicritères (granulométrie, etc.) met en évidence la variabilité importante des chènevottes et permet de les classer en trois groupes. Les essais réalisés sur le BC permettent d’obtenir les performances mécaniques faibles, moyennes et élevés comme prédit. Un facteur d’environ 10 a été obtenu entre le minimum et le maximum observés pour la contrainte de compression. Cependant, la masse volumique et la conductivité thermique sont de faible variabilité. D’après les analyses réalisées, il existe vraisemblablement les interactions chimiques liant-chènevotte qui affectent les performances mécaniques. Ainsi, une étude approfondie sur la composition chimique de la chènevotte et de son interaction avec liant peut permettre de mieux comprendre la réponse mécanique du BC.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
Wavefront dislocations in graphene systems revealed by transport measurement
Creators: name: Zhuang, Yu-Chen
name: Sun, Qing-Feng
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The wavefront dislocation is an important and ubiquitous phenomenon in wave fields. It is closely related to the phase singularity in a wave function. Some recent studies have verified that the wavefront dislocations in the local density of states (LDOS) map can well manifest the intrinsic topological characteristics in graphene and some topological systems. Different from these previous schemes, we raise a transport method to measure such wavefront dislocations in monolayer and Bernal-stacked bilayer graphene. Combining analytical analysis and numerical calculation, we find phase singularities naturally appear in the transmission coefficients between different sublattices, due to the intervalley interference on the electron propagating paths. These phase singularities could contribute wavefront dislocations in the conductance map. Additionally, in bilayer graphene, the wavefront dislocations are found to remain robust even though the tip is coupled to multiple sublattices. Biased bilayer graphene is also explored. Our scheme provides a new transport routine to explore valley-related topological properties of materials.
description: 15 pages, 9 figures
Estimation de l’état de corrosion de l’acier dans le béton armé par mesure de résistivité électrique
Creators: name: NGUYEN, A. Q.
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: L’objectif de cette étude est de déterminer l’état électrochimique des aciers du béton armé à l’aide d’une inversion de mesure de résistivité électrique. Une nouvelle procédure de mesure utilisant un dispositif quadripolaire linéaire est présentée. Des mesures de résistivité au droit des armatures sont réalisées et une procédure d’inversion numérique permettant de déterminer les caractéristiques du béton et de l’acier est mise en place. La présence de l’armature diminue significativement la résistivité apparente à cause d’un effet de court-circuit qui confine le courant à l’intérieur du volume de béton situé au-dessus et au voisinage de l’acier. Cette chute de résistivité dépend de différents facteurs tels que l’épaisseur d’enrobage, la résistivité du béton et surtout l’état électrochimique de l’acier. Les simulations numériques permettent de retrouver la résistivité réelle du béton ainsi que les paramètres électrochimiques de l’acier en utilisant le modèle électrochimique de Butler-Volmer. Les résultats obtenus montrent l’intérêt de cette méthodologie afin d’étudier le risque de corrosion de l’acier dans les structures en béton armé.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
Additional file 1: Figure S1-S7. of Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-Ă 1 secretion
Creators: name: Ren, Yu
name: Jia, Huan-huan
name: Xu, Yi-qi
name: Zhou, Xuan
name: Zhao, Xiao-hui
name: Wang, Yun-fei
name: Song, Xin
name: Zhu, Zhi-yan
name: Sun, Ting
name: Dou, Yan
name: Tian, Wei-ping
name: Zhao, Xiu-lan
name: Kang, Chun-sheng
name: Mei, Mei
Publisher: name: figshare
Year: 2018
Subjects: Space Science
Cell Biology
Molecular Biology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Developmental Biology
Marine Biology

description: Showing supplementary results. (DOCX 8533Â kb)
Additional file 1 of Factors influencing the pre-hospital management of civilian burn mass casualty incidents in the 21st century: a scoping review
Creators: name: Lindquist, Andreas
name: Al-Azzawi, Resha
name: Risør, Torsten
name: Raatiniemi, Lasse
Publisher: name: figshare
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy

description: Supplementary file 1
Additional file 2 of Factors influencing the pre-hospital management of civilian burn mass casualty incidents in the 21st century: a scoping review
Creators: name: Lindquist, Andreas
name: Al-Azzawi, Resha
name: Risør, Torsten
name: Raatiniemi, Lasse
Publisher: name: figshare
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy

description: Supplementary file 2
Additional file 3 of Factors influencing the pre-hospital management of civilian burn mass casualty incidents in the 21st century: a scoping review
Creators: name: Lindquist, Andreas
name: Al-Azzawi, Resha
name: Risør, Torsten
name: Raatiniemi, Lasse
Publisher: name: figshare
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy

description: Supplementary file 3
MOESM3 of Genetic diversity of three surface protein genes in Plasmodium malariae from three Asian countries
Creators: name: Srisutham, Suttipat
name: Saralamba, Naowarat
name: Sriprawat, Kanlaya
name: Mayxay, Mayfong
name: Smithuis, Frank
name: Nosten, Francois
name: Pukrittayakamee, Sasithon
name: Day, Nicholas
name: Dondorp, Arjen
name: Imwong, Mallika
Publisher: name: figshare
Year: 2018
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 3. Accession numbers of amino acid sequences and gene IDs of six Plasmodium TRAP, AMA1, and P48/45 obtained from database.
Mixing order asymmetry in nanoparticle-polymer complexation and precipitation revealed by isothermal titration calorimetry
Creators: name: Vitorazi, Letícia
name: Berret, Jean-François
Publisher: name: arXiv
Year: 2024
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: In recent years, there has been a renewed interest in complex coacervation, driven by concerted efforts to offer novel experimental and theoretical insights into electrostatic charge-induced association. While previous studies have primarily focused on polyelectrolytes, proteins or surfactants, our work explores the potential of using cerium (CeO2) and iron (γ-Fe2O3) oxide nanoparticles (NPs) to develop innovative nanomaterials. By combining various charged species, such as polyelectrolytes, charged neutral block copolymers and coated NPs, we study a wide variety of complexation patterns and compare them using isothermal titration calorimetry, light scattering and microscopy. These techniques confirm that the titration of oppositely charged species occurs in two steps: the formation of polyelectrolyte complexes and subsequent phase (or microphase) separation, depending on the system studied. Across all examined cases, the entropic contribution to the total free energy surpasses the enthalpic contribution, in agreement with counterion release mechanisms. Furthermore, our investigation reveals a consistent asymmetry in the reaction enthalpy associated with the secondary process, with exothermic profiles observed upon the addition of cationic species to anionic ones and endothermic profiles in the reverse case.
Purine analogues as potential CDK9 inhibitors: New pyrazolopyrimidines as anti-avian influenza virus
Creators: name: Khedr, Mohammed A.
name: Zaghary, Wafaa A.
name: Elsherif, Gihad E.
name: Azzam, Rasha A.
name: Elgemeie, Galal H.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Cyclin dependent kinases (CDKs) are a group of enzymes involved in different phases of the cell cycle. In addition, it has been reported that CDK9 could be used as a crucial target for the development of antiviral drugs such as purine analogues; roscovitine and dinaciclib. A new series of benzothiazolyl pyrazolopyrimidine carboxamide derivatives were synthesized and evaluated for their antiviral activity against avian influenza "bird flu" (H5N1). The novel compounds were synthesized via the reaction of pyrazolo carboxamide derivatives with different derivatives of ylidine benzothiazole. The reaction proceeded via a Michael addition pathway. Antiviral activity was determined using a plaque reduction assay against the H5N1 virus. Five compounds showed the highest inhibitory activity in the range of 61.6 to 71.6% at 0.1 μmol/mL. Based on a molecular docking study, an enzyme assay was carried out against CDK9 for the previously mentioned top-ranked compounds. It was found that compound 11f was the most potent inhibitor of CDK9 with an IC50 of 0.062 μmol/mL. A QSAR model was built to determine the hidden feature responsible for the biological activity of the novel compounds. It was found that two sets of descriptors, 3 D Potential energy descriptors and 2 D Atom Counts and Bond Counts descriptors, were correlated to a linear model with RMSE and r2 coefficient values of 0.75 and 0.80, respectively. A molecular dynamic simulations study of 11f over 10 ns against dinaciclib showed that both 11f and dinaciclib achieved equilibrium at 2 Å.
Modélisation des couplages poromécaniques et chimiques des bétons de structures atteints de formation d’ettringite différée (DEF)
Creators: name: MORENON, Pierre
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: Les réactions de gonflement interne (RGI) qui dégradent le béton, posent des problèmes de durabilité et de sûreté des ouvrages. Ces pathologies se développent préférentiellement dans les structures humides et massives telles que les barrages. Dans le but de prédire l’évolution des dégradations, des modèles numériques sont développés en partenariat avec EDF. Ils permettent la modélisation du comportement du béton des barrages à partir de tests de laboratoire sur éprouvettes, de données initiales des matériaux et de relevés in situ. Dans ce travail, un modèle poromécanique permet la prise en compte de la fissuration anisotrope, qu’elle soit localisée (structurelle) ou diffuse (issue de Formation d’Ettringite Différée (DEF)). Suite à un chargement ou un confinement de la structure, le gonflement du béton peut être reporté dans une ou plusieurs directions libres. L’endommagement y devient anisotrope. La prise en compte de ce phénomène poromécanique est nécessaire dans la modélisation des ouvrages pour retrouver les déplacements, les contraintes et le faciès de fissuration in situ. La simulation, validée par ces indicateurs, permet de prédire la sûreté et la durabilité des structures atteintes.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
Multi-scale analysis of drying: effect of aggregates
Creators: name: MALBOIS, Marie
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: Le séchage de structure en béton est à l’origine de deux mécanismes de fissuration : un surfacique dû au gradient hydrique et un interne dû à l’incompatibilité des déformations entre la pâte de ciment et les granulats. La difficulté de découpler ces phénomènes avec des méthodes expérimentales classiques rend difficile la quantification de l’effet des hétérogénéités. L’étude paramétrique présentée dans ce papier s’appuie sur une campagne expérimentale paramétrique sur matériaux cimentaires modèles, où la quantité de granulats et leur diamètre sont contrôlés, afin de déterminer l’impact des inclusions et du séchage. Les éprouvettes de plusieurs formulations sont soumises à du séchage et testées afin de déterminer l’évolution de leur propriétés mécaniques. Les résultats montrent l’impact important de ces deux paramètres sur les déformations différées et l’endommagement des matériaux cimentaires lors du séchage.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
Elaboration et caractérisation mécanique, thermique et hygrique de composites bio-sourcés à base d’argile
Creators: name: MAZHOUD, Brahim
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: Cette étude s’intéresse à l’utilisation d’argile comme liant pour élaborer des composites chanvre-argile. L’argile est issue de boues de lavage d’un site de production de graviers. Afin d'améliorer les propriétés mécaniques des composites, l’argile est stabilisé par des liants commerciaux. Les composites sont élaborés avec différents rapports chanvre sur liant. Le rapport chanvre sur liant est estimé en se référant aux mélanges traditionnels de béton de chanvre utilisés pour les applications dalle, mur et toit. Les performances mécaniques, thermiques et hygriques sont mesurées. La caractérisation mécanique se base sur la mesure de la résistance en compression, de la résistance en traction par fendage et du module élastique. La caractérisation thermique est basée sur la mesure de conductivité thermique à 23°C-50%HR. La caractérisation hygrique est basée sur la mesure de la valeur tampon hygrique à 23°C. Les résultats montrent que les performances mécaniques, thermiques et hygriques des composites sont semblables à celles de béton de chanvre ayant la même densité. Les propriétés mesurées sont intéressantes : leur conductivité thermique est faible (0.102 à 0.129 W/(m.K)) et les matériaux s’avèrent être d’excellents régulateurs hygriques (MBV > 2 W/(m².%RH)).
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
Additional file 3: of Mortality impact of an increased blood glucose cut-off level for hypoglycaemia treatment in severely sick children in Malawi (SugarFACT trial): study protocol for a randomised controlled trial
Creators: name: Baker, Tim
name: Dube, Queen
name: Langton, Josephine
name: Hildenwall, Helena
Publisher: name: figshare
Year: 2018
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy

description: Study consent form (in English). (DOCX 31 kb)
Utilisation des renforcements par composites collés pour l’augmentation de la durée de vie en fatigue des structures métalliques anciennes
Creators: name: LEPRETRE, Emilie
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: Après la corrosion, la fatigue représente la deuxième cause d’endommagement des structures métalliques anciennes. Celle-ci se manifeste par l’apparition puis la propagation de fissures dans les zones les plus fortement sollicitées. Dans le cas des assemblages rivetés, l’amorce des fissures a lieu préférentiellement en bord de perçage, rendant difficile leur détection. Dans ce contexte, l’objectif du travail réalisé a été d’étudier l’efficacité d’un renforcement par composites collés dans le cas de fissures émanant de trous de rivets. Des essais ont été réalisés sur éprouvettes de petites dimensions, constituées de matériaux métalliques anciens de l’époque, tels que le fer puddlé et l’acier doux, et renforcées à l’aide de différents procédés de renforcement par plats composites collés. Les résultats obtenus ont permis, d’une part, de quantifier le ralentissement de la propagation de fissures, et d’autre part de mener une analyse en terme de facteur d’intensité de contraintes. Un premier modèle analytique de propagation a pu être proposé, puis un modèle numérique a été mis en place afin de permettre la transposition des résultats à d’autres géométries d’éléments rencontrés sur ouvrage.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
Comportement mécanique des structures hybrides GFRPbéton
Creators: name: KOAIK, Alaa
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: L’utilisation des composites dans la construction des bâtiments ou des ouvrages d’art est de plus en plus importante grâce à leurs atouts indiscutables. Cependant, leur essor est ralenti par certaines faiblesses dont l’une des plus importantes est leur souplesse qui induit des déplacements élevés et des risques d’instabilités importants qui ne permettent pas d’exploiter tout le potentiel de ces matériaux. Dans le cas d’éléments de structure fléchis, une des solutions consiste à associer les profilés composites à une dalle en béton armé. Dans cette étude, après une phase de caractérisation des différents matériaux et de l’interface par l’essai push-out, nous avons testé 3 modes de connexion sur des éléments structuraux (poutres) de différentes portées. Les résultats d’essais montrent le comportement correspondant à chaque mode connexion : la connexion par butées mécaniques simples est à ce jour celle qui s’avère la plus efficace. Les mesures sont également comparées aux résultats obtenus par calcul sur des modèles de poutres multicouches. Les écarts modèles / calculs restent acceptables sauf à proximité de l’interface où les déformations peuvent être affectées par la fissuration du béton qui reste difficile à prédire de façon précise.
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
Problems of Learning English in the Era of Pandemic Covid-19 at MTsN Sorong
Creators: name: Dabamona, Miftahulfadlik
Publisher: name: figshare
Year: 2022
Subjects: subject: 130204 English and Literacy Curriculum and Pedagogy (excl. LOTE, ESL and TESOL)
subject: FOS: Educational sciences

description: The current situation makes educational units to carry out learning at home by utilizing existing technology. This study aims to find out and dig deeper into the problems faced by students when learning English during the COVID-19 pandemic at MTsN students in Kota Sorong The researcher used a descriptive qualitative approach. This research was conducted at MTsN Kota Sorong involving 9F grade students. This study also uses data triangulation to test the validity of the data by combining observations, interviews and documents as data collection instruments to obtain data from sources. The results of this study are the views and experiences of students against obstacles during the English learning process during the COVID-19 pandemic, using Google Classroom as a support for student learning at home. This study also found obstacles in the internet network and the environment used as a learning place that did not support learning during the COVID-19 pandemic.
Reactivity of 5-carboxycytosine toward addition and hydrogen abstraction by ·OH in acetonitrile: a computational study
Creators: name: Lingxia Jin
name: Mengdan Lv
name: Yawen Wei
name: Jiufu Lu
name: Suotian Min
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Computational Biology

description: Two distinct mechanisms of -mediated 5-carboxylcytosine (5-caCyt) at the CBS-QB3 approach with polarizable continuum model in acetonitrile have firstly been explored, the addition reaction (paths R1 and R2), the H-atom abstraction reaction (paths R3-R6), respectively. It indicates that the addition of to the C5 = C6 double bond of 5-caCyt remains more favourable than the H-atom abstraction, whether in the gas or aqueous phase. Meanwhile, there is a little difference in the free energy barrier between acetonitrile and water, showing that the solvent has small impact on the reactivity of -mediated 5-caCyt.
MOESM4 of Genetic diversity of three surface protein genes in Plasmodium malariae from three Asian countries
Creators: name: Srisutham, Suttipat
name: Saralamba, Naowarat
name: Sriprawat, Kanlaya
name: Mayxay, Mayfong
name: Smithuis, Frank
name: Nosten, Francois
name: Pukrittayakamee, Sasithon
name: Day, Nicholas
name: Dondorp, Arjen
name: Imwong, Mallika
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 4. Amino acid identity of non-cytoplasmic region TRAP, AMA1, and P48/45 within six Plasmodium species.
Академический вестник УралНИИпроект РААСН,Выпуск 1 (52) 2021
Creators: name: УралНИИпроект
Publisher: name: УралНИИпроект
Year: 2021

description: Академический вестник УралНИИпроект РААСН,Выпуск 1 (52) 2021
Skin dose in breast radiation therapy: Monte Carlo calculations from deformed vector fields (DVF)-driven CT images
Creators: name: Arbor, Nicolas
name: Bartolucci, Laurent
name: Dai, Botao
name: Azhar, Halima El
name: Galmiche, Pierre
name: Jarnet, Delphine
name: de Papigny, Michel de Mathelin
name: Meyer, Philippe
name: Seo, Hyewon
Publisher: name: arXiv
Year: 2024
Subjects: subject: Medical Physics (physics.med-ph)
subject: FOS: Physical sciences

description: Skin dose in radiotherapy is a key issue for reducing patient side effects, but dose calculations in this high-gradient region remains a challenge. To support radiation therapists and medical physicist in their decisions, a computational tool has been developed to systematically recalculate the skin dose for each treatment session, taking into account changes in breast geometry. This tool is based on Monte Carlo skin dose calculations from deformed vector fields (DVF)-driven CT images, using 3D-scanner data. The application of deformation fields to the initial patient CT, as well as the validation of Monte Carlo skin dose calculations and comparison with TPS algorithm, are presented. The tool is currently being evaluated using data from a clinical study involving 60 patients (MorphoBreast3D).
Modélisation numérique des poutres en béton armé renforcées avec des PRFC par la technique NSM
Creators: name: KHENE, Ahmed
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: La méthode NSM a été utilisée ces dernières années pour le renforcement des poutres avec des polymères renforcés en fibre de carbone (PRFC). Une étude numérique a été effectuée sur des poutres en béton armé de sections rectangulaires, renforcées avec des PRFC en utilisant la technique NSM à travers le code de calcul ATENA 2D. Les simulations numériques par éléments finis ont été comparées avec des essais expérimentaux testés par d'autres chercheurs sur des échantillons renforcés avec des bandes en PRFC. Dans l'ensemble, les charges maximales prévisionnelles de modèle par éléments finis et les flèches à mi-portée concordaient assez bien avec les résultats expérimentaux correspondantes à tous les stades de chargement en flexion. Le modèle par éléments finis développé est adapté comme outil pratique et économique, en particulier dans les études paramétriques pour la modélisation et l'analyse précises du renforcement de la flexion des poutres en béton armée avec un renforcement NSM-PRF
description: Academic Journal of Civil Engineering, Vol 35 No 1 (2017): Special Issue - RUGC 2017 Nantes
The Propensity to Learn Shared Cultural Knowledge from Social Group Members: Selective Imitation in 18-month-olds
Creators: name: Altınok, Nazlı
name: Király, Ildikó
name: Gergely, György
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Fourteen-month-olds selectively imitated a sub-efficient means (illuminating a lightbox by a head-touch) when this was modeled by linguistic ingroup members in video-demonstrations. A follow-up study with slightly older infants, however, could replicate this effect only in a video-demonstration context. Hence it still remains unclear whether infants’ apparent tendency to be selective in learning opaque manners of novel skills from linguistic ingroup members is, indeed, a characteristic constraining property of cultural knowledge transmission that can be reliably manifested in live demonstration contexts that are more representative of naturalistic learning environments. To answer this question, we aimed to replicate the original study using live demonstration with a group of older infants (N = 48; 28 females). We found that eighteen-month-olds imitated the opaque manner of sub-efficient means action as a function of whether the demonstrator was a speaker of their own language. In a no-demonstration control group, infants relied on the self-discovered efficient means (hand-action), just like infants observing the foreign speaker. These findings suggest that selectivity in learning sub-efficient opaque actions from linguistic ingroups has evolved to support transmission of culture-specific manner of action practices shared within social groups.
title: OFROM: interview avec unine15b57m
Creators: name: Delafontaine, François
name: Ehinger, Maude
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.b6f92u98.v2#97658720bac1a38059d58a70d3340482843c6db1
Expected Improvement applied to an industrialcontext -- Prediction of new geometries increasing theefficiency of fans
Creators: name: Lagnoux, Agnès
name: Nguyen, T. M. Ngoc
name: Demory, Bruno
name: Henner, Manuel
Publisher: name: arXiv
Year: 2024
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: In automotive industry, client needs evolve quickly in a competitiveness context, particularly, regarding the fan involved in the engine cooling module. This study has been done in cooperation with the automotive supplier Valeo. Here, we propose to use the Kriging interpolation and the Expected Improvement algorithm to provide new fan designs with high performances in terms of eciency. As far as we know, such a use of Kriging and Expected Improvement methodologies are innovative and provide really promising results.
Additional file 1: of Chinese Cervicocephalic artery dissection study (CCADS): rationale and protocol for a multicenter prospective cohort study
Creators: name: Zhu, Zhu
name: Xu, Yuyuan
name: Wang, Yilong
name: Zhou, Zhenhua
name: Han, Xiang
name: Liu, Aihua
name: Peng, Jing
name: Xu, Yi
name: Wang, Luyao
Publisher: name: figshare
Year: 2018
Subjects: Biological Sciences not elsewhere classified
Developmental Biology
Science Policy

description: CCADS collaborative group. Names of 56 centers participating the study and the corresponding principle investigator in each center. (DOCX 58 kb)
Children’s Developing Understanding of the Subjectivity of Intentions – A Case of “Advanced Theory of Mind”
Creators: name: Schünemann, Britta
name: Proft, Marina
name: Rakoczy, Hannes
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: When and how do children develop an understanding of the subjectivity of intentions? Intentions are subjective mental states in many ways. One way concerns their aspectuality: Whether or not a given behavior constitutes an intentional action depends on how, under which aspect, the agent represents it. Oedipus, for example, intended to marry Yocasta, but did not intend to marry his mother (even though in fact, but unbeknownst to him, Yocasta was his mother). In the present study, we investigated the trajectories and determinants of children’s developing understanding of (less dramatic forms of) the aspectuality of intentions. In two studies, children aged 3–9 observed an agent who acted intentionally but based on some mis-representation regarding the target of her action. The agent grasped a box that contained A and B while believing that it only contained A but not B. Children were asked about the aspectuality of the agent’s intention (in particular, whether she intended to grasp B). When asked to do so spontaneously, children younger than 8 failed (falsely claiming that the agent intended to grasp B). In contrast, in a simplified format in which children were scaffolded through the required inferential chains, children from age 6 succeeded. Children’s general capacity for meta-representation appeared to be necessary but not sufficient by itself for understanding the aspectuality of intentions. The present findings suggest that the appreciation of the aspectuality of intentions is part of an advanced theory of mind that develops in much more protracted ways than basic theory of mind.