cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Executive function is inversely correlated with physical function: the cognitive profile of adult spinal muscular atrophy (SMA)
Creators: name: Mix, Lucas John
name: Schreiber‑Katz, Olivia
name: Wurster, Claudia D.
name: Uzelac, Zeljko
name: Platen, Sophia
name: Gipperich, Christina
name: Ranxha, Gresa
name: Wieselmann, Gary
name: Osmanovic, Alma
name: Ludolph, Albert C.
name: Petri, Susanne
name: Lulé, Dorothée
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Spinal muscular atrophy
subject: SMA
subject: Cognitive adaptation
subject: Edinburgh cognitive and behavioural ALS screen (ECAS)
subject: Reading the mind in the eyes test
subject: Hammersmith functional motor scale expanded (HFMSE)
subject: DDC 610 / Medicine & health
subject: Muscular atrophy, Spinal
subject: Cognition
subject: Social cognition
subject: Executive function
subject: Spinale Muskelatrophie
subject: Kognition

description: Background: Spinal muscular atrophy (SMA) issues from mutations in the survival of motor neuron (SMN) 1 gene. Loss or reduction of the SMN protein results in progressive muscle weakness. Whether this protein deficiency also affects cortical function remains unclear. While no data on adult patients exists so far, prior studies in children with SMA indicate cognitive abilities equal or even superior to healthy controls. This may suggest a possible compensatory—neuropsychological and interactional—process. The goal of this study was to assess the cognitive profile of adult patients with SMA, with a special focus on social cognition as a potential candidate for enhanced cognitive function through compensatory processes. Methods: In a cross-sectional design, N = 31 adult SMA patients (types II and III) were assessed for language, verbal fluency, memory, visuospatial abilities and executive function with the Edinburgh Cognitive and Behavioural ALS Screen and for social cognition with the Reading the Mind in the Eyes Test. Physical function was evaluated using the Hammersmith Functional Motor Scale Expanded. N = 19 neurologically healthy controls were matched with patients for age, sex and years of education. Results: In none of the abovementioned cognitive domains significant differences between SMA patients and controls were found. Among patients, no differences between type II SMA and type III SMA were detected for any domain. However, a trend towards better social cognition in patients with type II SMA, compared to those with type III SMA was observed. Furthermore, a significant inverse correlation of physical function and executive function was detected: lower motor function was associated with a better executive function. Conclusions: This study shows cognitive abilities in adult SMA in the normal range for all assessed domains. Thus, reduction of SMN protein has no obvious negative impact on cognitive function. Executive functions are identified as the only cognitive domain correlated with disease severity. Therefore, executive functions may play a role in the adaptation to physical restrictions in SMA, making them a promising target for future research.
State, Silk and Ethnicity of the Suai in Pueai Mai Village, Sisaket Province
Creators: name: Tanapa Sakunasingh
name: Jaggapan Cadchumsang
Publisher: name: Center for Research on Plurality in the Mekong Region (CERP)
Year: 2017
Subjects: pha kep, Suai, ethnicity, identity, silk

description: Journal of Mekong Societies, 13, 2
Rethinking China's Claim in the South China Sea: The Engagement between International Relations and International Law
Creators: name: Thapiporn Suporn
Publisher: name: Center for Research on Plurality in the Mekong Region (CERP)
Year: 2017
Subjects: China, South China sea disputes, engagement between international relations and international law, historic rights, land reclamation, South China Sea arbitration

description: Journal of Mekong Societies, 13, 2
sj-docx-2-smo-10.1177_20503121231176637 – Supplemental material for A mixed-methods assessment of community-engaged learning in a Master of Public Health program
Creators: name: Thaivalappil, Abhinand
name: Coghlin, Rachel
name: Bell, Courtney
name: Dougherty, Brendan
name: Duench, Stephanie
name: Janicki, Rachelle
name: Papadopoulos, Andrew
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, sj-docx-2-smo-10.1177_20503121231176637 for A mixed-methods assessment of community-engaged learning in a Master of Public Health program by Abhinand Thaivalappil, Rachel Coghlin, Courtney Bell, Brendan Dougherty, Stephanie Duench, Rachelle Janicki and Andrew Papadopoulos in SAGE Open Medicine
Risque d'érosion hydrique entre fragilité des équilibres environnementaux et perspectives de durabilité: Cas du bassin d’Oued El Abed (Maroc nord-est)
Creators: name: SBAI, Abdellkader
name: MOUADILI, Omar
Publisher: name: figshare
Year: 2022
Subjects: subject: 70101 Agricultural Land Management
subject: FOS: Other agricultural sciences

description: L'érosion hydrique est l’un des risques inquiétants qui menacent le milieu physique et la stabilité humaine. Le bassin d’oued El Abed, est sujet à ce phénomène depuis longtemps, ce qui a induit des mutations importantes et a touché divers domaines économiques, sociaux et environnementaux. Ainsi, la problématique de cette étude est axée sur l’étude de l’érosion et son évaluation dans ce bassin. Le bassin d’oued El Abed est situé au sud-ouest de Taourirt, dans la partie ouest du couloir de Guercif-Oujda et comprend une partie de la plaine de Tafrata. Sa surface est de 317 km² à sa confluence avec oued Moulouya. Pour étudier l'érosion dans ce bassin, nous avons, d’une part analysé les données quantitatives et qualitatives disponibles et, d’autre part, réalisé des mesures sur le terrain par simulation de pluie (intensité de 60 mm/h durant 10 mn). L'estimation de la perte en sol a été faite en se basant sur l'équation universelle de perte en sol (USLE). L'inventaire des diverses manifestations et formes d'érosion hydrique dans le bassin de l'oued El-Abed montre clairement qu'il s'agit d'une forte activité morphodynamique caractérisée par un ruissellement diffus et concentré, des ravinements, des extensions latérales des vallées. Après avoir calculé les différents facteurs de l’USLE, on a constaté que 4,7% de la surface du bassin serait fortement érodée. La dégradation spécifique moyenne a été estimée à 6,4 tonnes/ha/an. Les mesures de simulation de pluie ont montré des différences nettes entre les utilisations des terres. En effet, les coefficients de ruissellement sont faibles dans les parcelles couvertes de végétation et celles cultivées parallèlement aux courbes de niveau. Par contre, sur les sols nus et les pentes fortes, ce coefficient est élevé. Les quantités de sols détachées varient de 0,014 pour les parcelles couvertes à 2,9 t/ha pour celles nues et à forte pente. L’érosion dans le bassin d’El Abed est due à sa fragilité naturelle mais surtout aux actions anthropiques (mise en culture, surpâturage).
Ecosystem Services: Derivation and Critique of the Political Ecology Perspective
Creators: name: Preuk Taotawin
name: Buapan Prompakping
Publisher: name: Center for Research on Plurality in the Mekong Region (CERP)
Year: 2017
Subjects: ecosystem services, millennium ecosystem assessment, neoliberalism, payment for ecosystem services, political ecology

description: Journal of Mekong Societies, 13, 2
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 247 (31. Jg.), September 2001
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Uni Ulm intern
subject: Universities; Germany; Ulm
subject: Ulm / Universität

description: N/A
sj-docx-1-ema-10.1177_17411432231177835 - Supplemental material for Interplay between leadership and school-level conditions: A review of literature on the Teaching and Learning International Survey (TALIS)
Creators: name: Ahn, Joonkil
name: Wang, Yinying
name: Lee, Yujin
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Education
subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business

description: Supplemental material, sj-docx-1-ema-10.1177_17411432231177835 for Interplay between leadership and school-level conditions: A review of literature on the Teaching and Learning International Survey (TALIS) by Joonkil Ahn, Yinying Wang and Yujin Lee in Educational Management Administration & Leadership
IPBES BBA Chapter 6. Snowballing review for critical approaches to financial regulators and central banks
Creators: name: Prodani, Klaudia
Publisher: name: Zenodo
Year: 2024
Subjects: IPBES
Business and biodiversity assessment
Chapter 6

description: The review corresponds to Chapter 6 of the IPBES business and biodiversity assessment. This snowballing review was conducted to collate literature related to central banks and financial supervisors with the aim of understanding where articles related to these actors also reference biodiversity.
Additional file 2 of Targeted next-generation sequencing and long-read HiFi sequencing provide novel insights into clinically significant KLF1 variants
Creators: name: Ye, Luyi
name: Wang, Chen
name: Li, Aijing
name: Li, Minghao
name: Pi, Yan
name: Yang, Jingmin
name: Zhu, Ziyan
name: Lu, Daru
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: Supplementary Material 2
The Process of Information Exposure and Demand for Atteding Activities Related to Thai Cultural Universals of the CLMV
Creators: name: Kanchana Chokriensukchai
Publisher: name: Center for Research on Plurality in the Mekong Region (CERP)
Year: 2017
Subjects: Thai culture, media, tourism, CLMV countries

description: Journal of Mekong Societies, 13, 2
Risque d'érosion hydrique entre fragilité des équilibres environnementaux et perspectives de durabilité
Creators: name: SBAI, Abdellkader
name: MOUADILI, Omar
Publisher: name: figshare
Year: 2022
Subjects: subject: 70101 Agricultural Land Management
subject: FOS: Other agricultural sciences

description: L'érosion hydrique est l’un des risques inquiétants qui menacent le milieu physique et la stabilité humaine. Le bassin d’oued El Abed, est sujet à ce phénomène depuis longtemps, ce qui a induit des mutations importantes et a touché divers domaines économiques, sociaux et environnementaux. Ainsi, la problématique de cette étude est axée sur l’étude de l’érosion et son évaluation dans ce bassin. Le bassin d’oued El Abed est situé au sud-ouest de Taourirt, dans la partie ouest du couloir de Guercif-Oujda et comprend une partie de la plaine de Tafrata. Sa surface est de 317 km² à sa confluence avec oued Moulouya. Pour étudier l'érosion dans ce bassin, nous avons, d’une part analysé les données quantitatives et qualitatives disponibles et, d’autre part, réalisé des mesures sur le terrain par simulation de pluie (intensité de 60 mm/h durant 10 mn). L'estimation de la perte en sol a été faite en se basant sur l'équation universelle de perte en sol (USLE). L'inventaire des diverses manifestations et formes d'érosion hydrique dans le bassin de l'oued El-Abed montre clairement qu'il s'agit d'une forte activité morphodynamique caractérisée par un ruissellement diffus et concentré, des ravinements, des extensions latérales des vallées. Après avoir calculé les différents facteurs de l’USLE, on a constaté que 4,7% de la surface du bassin serait fortement érodée. La dégradation spécifique moyenne a été estimée à 6,4 tonnes/ha/an. Les mesures de simulation de pluie ont montré des différences nettes entre les utilisations des terres. En effet, les coefficients de ruissellement sont faibles dans les parcelles couvertes de végétation et celles cultivées parallèlement aux courbes de niveau. Par contre, sur les sols nus et les pentes fortes, ce coefficient est élevé. Les quantités de sols détachées varient de 0,014 pour les parcelles couvertes à 2,9 t/ha pour celles nues et à forte pente. L’érosion dans le bassin d’El Abed est due à sa fragilité naturelle mais surtout aux actions anthropiques (mise en culture, surpâturage).
title: Grenzen der Fernsehwerbung bei Vorschulkindern
Creators: name: Weiss, Tina
Year: 2009

description: Kinder stellen für Werbetreibende schon seit längerem eine nicht unrelevante Zielgruppe dar. Zahlreiche Publikationen und Untersuchungen zum Thema Kinder und (Fernseh-) Werbung werden häufig von Begriffen wie „geheime Verführung“, „schutzlose Objekte“ oder „Manipulation“ begleitet. Ohne Zweifel ist eine gewisse Wirkung der Werbung auch bei Kindern nicht auszuschließen. Dennoch ist Fernsehen und somit auch Fernsehwerbung Bestandteil der Alltagswelt und spielt eine nicht unbedeutende Rolle in der Sozialisation von Kindern. Es ist anzunehmen, dass Wirkungen auf die Einstellung zu bestimmten Produkten durch Fernsehwerbung nicht bedingungslos auftreten und es somit gewisse Grenzen der Werbewirkung bei Vorschulkindern gibt. Die Ergebnisse eines Experiments mit insgesamt 80 Vorschulkindern zwischen drei und sechs Jahren, aus denen Rückschlüsse auf die kurzfristige Wirkung von Fernsehwerbung auf die Einstellung zu Artikeln der Produktgruppen „Süßigkeiten“ und „Getränke“ gezogen werden können, lassen vermuten, dass Kinder im Vorschulalter durch Fernsehwerbung, welche sich bei Vorschulkindern grundsätzlich großer Beliebtheit erfreut, tatsächlich nicht ohne Einschränkungen manipuliert und verführt werden. So konnten bei der Auswertung der Ergebnisse zum Großteil, nach der Rezeption der Fernsehspots keine signifikanten Veränderungen bezüglich der Einstellung zu den darin gezeigten Produkten bzw. der Affinität zu einer bestimmten Produktgruppe festgestellt werden. Lediglich bei neuen, den Kindern eher unbekannten Produkten, lässt sich eine kurzfristige Wirkung der gezeigten Werbespots diagnostizieren. Mögliche Erklärungen für die gewonnenen Ergebnisse werden in einem abschließenden Resümee in einer Zusammenführung mit bereits vorliegenden theoretischen Erkenntnissen diskutiert.
description: Advertisers tend to see children as a target groop, which is particularly and highly relevant in creating commercials. In many publications and researches concerning children and TV-comercials very often terms like “secret temptation”, “defenceless objects” or “manipulation” are mentioned. Without any doubt certain effects of commercials can also be noticed in children’s perception. Nevertheless watching TV and furthermore TV-spots play an important part in the everyday life and at the process of children’s socialization. Certain borders of affects and possible influences of TV-commercials can be considered. An experiment with 80 three- to six-year-old kids leads to the result, that suspectively children cannot be temptated and manipulated without any reservation. The results show, that there are no significant changes concerning the attitude towards producs after watching specific TV-commercials. Only commercials of new and unknown products can cause relevant effects concerning preferences.
Evaluating benefits of requirement categorization in natural language specifications for review improvements
Creators: name: Ott, Daniel
name: Raschke, Alexander
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Classified requirements
subject: Experimental software engineering
subject: Review
subject: Topic landscape
subject: Topic
subject: DDC 004 / Data processing & computer science
subject: Inspection
subject: Requirements engineering
subject: Anforderungsdefinition
subject: Automatische Klassifikation

description: One of the most common ways to ensure the quality of industry specifications is technical review, as the documents are typically written in natural language. Unfortunately, review activities tends to be less effective because of the increasing size and complexity of the specifications. For example at Mercedes-Benz, a specification and its referenced documents often sums up to 3.000 pages. Given such large specifications, reviewers have major problems in finding defects, especially consistency or completeness defects, between requirements with related information that are spread over large or even different documents. The classification of each requirement according to related topics is one possibility to improve the review efficiency. The reviewers can filter the overall document set according to particular topics to check consistency and completeness between the requirements within one topic. In this paper, we investigate whether this approach really can help to improve the review situation by presenting an experiment with students reviewing specifications originating from Mercedes-Benz with and without such a classification. In addition, we research the experiment participants’ acceptance of an automatic classification derived from text classification algorithms compared to a manual classification and how much manual effort is needed to improve the automatic classification. The results of this experiment, combined with the results of previous research, lead us to the conclusion that an automatic pre-classification is an useful aid in review tasks for finding consistency and completeness defects.
Additional file 3 of Targeted next-generation sequencing and long-read HiFi sequencing provide novel insights into clinically significant KLF1 variants
Creators: name: Ye, Luyi
name: Wang, Chen
name: Li, Aijing
name: Li, Minghao
name: Pi, Yan
name: Yang, Jingmin
name: Zhu, Ziyan
name: Lu, Daru
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: Supplementary Material 3
The important role of immunotherapies in acute myeloid leukemia
Creators: name: Greiner, Jochen
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: DDC 610 / Medicine & health
subject: Leukemia, Myeloid, Acute; Therapy
subject: Immunotherapy
subject: Akute myeloische Leukämie
subject: Immuntherapie

description: Kein Abstract verfügbar
title: Contemporary franchise revitalisation: The soft reboot
Creators: name: McDonald, Scott
Publisher: name: University of Glasgow
Year: 2024

description: This thesis aims to bring the term ‘soft reboot’ into regular academic use. Throughout the following chapters the term soft reboot is explained in detail, differentiating it from standard ‘hard’ reboots. The defining characteristic of a soft reboot is that it must maintain some of level of franchise canon; this thesis therefore highlights the shortcomings of previous definitions of the term ‘reboot’ in relation to film. I focused primarily on twelve key soft reboots, both to better illustrate what constitutes a soft reboot and to provide continuity between the various chapters that make up this dissertation. A thorough literature review was conducted which helped to better situate my own work within the current academic discourse surrounding reboot studies. Then, the key stages of a film’s life cycle were examined in turn to elucidate how soft reboots are texts largely concerned with targeting the audience’s feelings of nostalgia for the original films in their franchise. These stages were production, promotion, text, and reception. This research advances the field of reboot study by broadening the scope of analysis to include those films which reboot or revitalise their franchise without removing elements from canon, modernising our understanding of what a reboot can be to better suit its current usage, particularly since the soft reboot’s explosion in popularity in 2015. These findings highlight the opportunities for further study in the field, focusing more specifically on how soft reboots function in particular franchises. Though this thesis conducts such analysis and research, its purpose is primarily illustrative to better explain exactly what a soft reboot is and how it operates.
sj-docx-2-smo-10.1177_20503121231178102 – Supplemental material for A systematic review and meta-analysis protocol on knowledge of obstetric danger signs and associated factors among women in Africa
Creators: name: Moloro, Abdulkerim Hassen
name: Waritu, Tejo Ushu
name: Haso, Mustefa Kasim
name: Ibrahim, Roda Mehadi
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, sj-docx-2-smo-10.1177_20503121231178102 for A systematic review and meta-analysis protocol on knowledge of obstetric danger signs and associated factors among women in Africa by Abdulkerim Hassen Moloro, Tejo Ushu Waritu, Mustefa Kasim Haso and Roda Mehadi Ibrahim in SAGE Open Medicine
Many-body entanglement and topology from uncertainties and measurement-induced modes
Creators: name: Pöyhönen, Kim
name: Moghaddam, Ali G.
name: Ojanen, Teemu
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present universal characteristics of quantum entanglement and topology through virtual entanglement modes that fluctuate into existence in subsystem measurements. For generic interacting systems and extensive conserved quantities, these modes give rise to a statistical uncertainty which corresponds to entanglement entropies. Consequently, the measurement-induced modes provide directly observable route to entanglement and its scaling laws. Moreover, in topological systems, the measurement-induced edge modes give rise to quantized and non-analytic uncertainties, providing easily accessible signatures of topology. Our work provides a much-needed direct method to probe the performance of emerging quantum simulators to realize entangled and topological states.
description: 9 pages, 6 figures. Updated due to publication
Power Relations in the Commodification of Local Culture: A Case Study of a Local Fair Organized at the Thung Samrit Memorial
Creators: name: Sunisa Pramong And Viyouth Chamruspanth
Publisher: name: Center for Research on Plurality in the Mekong Region (CERP)
Year: 2017
Subjects: power relations, commodification, local fair, Thung Samrit Memorial

description: Journal of Mekong Societies, 13, 2
Supplemental Material - A Latent Class Analysis of Personal Coping Resources and Depressive Symptoms Among Middle-Aged and Older Latinx Adults
Creators: name: Gutiérrez, Ángela
name: Thomas Tobin, Courtney
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110308 Geriatrics and Gerontology
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material for A Latent Class Analysis of Personal Coping Resources and Depressive Symptoms Among Middle-Aged and Older Latinx Adults by Ángela Gutiérrez and Courtney Thomas Tobin in Journal of Aging and Health
Fecal calprotectin as a predictor of gastrointestinal immune-related adverse events (CF-19): A prospective study - Excel data and supplementary tables
Creators: name: Cardeña, Ana
Publisher: name: Zenodo
Year: 2021

description: Background: Colitis is a frequent immune-related toxicity, without any biomarker that may predict its onset. It is endoscopically similar to intestinal inflammatory diseases, where fecal calprotectin (FC) is used as a biomarker to early-detect a relapse. We found contradictory evidence about FC and immunotherapy and no prospective study was already published. Methods: We present an analytical, observational and prospective study of one year's duration. We analyzed FCbasal, and then prior to each cycle until the sixth, ending with quarterly follow-up. For evaluating the predictive value of FC we estimated the area under the ROC curve for basal absolute values and for each cycle, and calculated its relative percentage change with respect to basal. We also planned to estimate sensitivity, specificity and predictive values indexes for different cut-off points. Because of lack of recruitment we did a preliminary analysis at the end of the initially estimated period before suggesting its prolongation. Results: 24 patients were included (19 male), diagnosed from lung cancer (n=15), head and neck, renal, bladder and colorectal cancer (n=2, each), melanoma (n=1). They were treated with Anti PD-1/PDL-1 mono therapy (n=18), combo with chemo (n=2), or combo with anti-CTLA4 (n=2). Three patients had G1 colitis and two, >=G2, all treated with anti-PD1 and before 6th cycle, as described on literature. ROC curve presents AUC 0,559 (CI95%:0,32-0,798) and RR for colitis taking FC value is 1,001 for each 10 units (p=0,493). Conclusion: Even though we must take into account the limitations of the study we cannot conclude that FC could be used as a predictor for detecting immune-mediated colitis.
Further development in the assessment of psychological flexibility: validation of the German committed action questionnaire
Creators: name: Terhorst, Yannik
name: Baumeister, Harald
name: McCracken, Lance M.
name: Lin, Jiaxi
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Committed action
subject: Psychological flexibility
subject: DDC 150 / Psychology
subject: Chronic pain
subject: Quality of life
subject: Chronischer Schmerz
subject: Therapieerfolg

description: Background: Psychological flexibility is considered a fundamental aspect of health. It includes six interrelated facets: 1) cognitive defusion, 2) acceptance, 3) contact with the present moment, 4) self-as-context, 5) values, and 6) committed action. To gain further insight into psychological flexibility and its effects on health, reliable and valid instruments to assess all facets are needed. Committed action is one facet that is understudied. A long and short version of a validated measure (CAQ and CAQ-8) have been developed in English. Currently, there are no German versions of the CAQ. Aim of this study is to validate German-language versions of these in a chronic pain population. Methods: The CAQ instructions and items were translated and evaluated in a chronic pain population (N = 181). Confirmatory factor analysis and Mokken scale analysis were conducted to evaluate the German questionnaires. Correlations with health outcomes, including quality of life (SF-12), physical and emotional functioning (MPI, BPI, PHQ-9, GAD-7), pain intensity, and with other facets of psychological flexibility (CPAQ, FAH-II) were investigated for convergent validity purposes. Scale reliability was assessed by the alpha, MS, lambda-2, LCRC, and omega coefficient. Results: A bifactor model consisting of one general factor and two methodological factors emerged from the analysis. Criteria for reliability and validity were met. Medium to strong correlations to health outcomes and other facets of psychological flexibility were found. Results were similar to the original English version. Conclusions: The present study presents a valid and reliable instrument to investigate committed action in German populations. Future studies could expand the present findings by evaluating the German CAQ versions in non-pain populations. The role of committed action and the wider psychological flexibility model in pain and other conditions deserves further investigation.
sj-pdf-4-vmj-10.1177_1358863X231169323 – Supplemental material for Immunologic profiles in patients with chronic limb-threatening ischemia undergoing endovascular revascularization
Creators: name: Li, Jun
name: Arora, Shilpkumar
name: Wheat, Heather
name: Dash, Siddhartha
name: Kimura, Stephen
name: Smith, Justin
name: Castro-Dominguez, Yulanka
name: Oommen, Clint
name: Hammad, Tarek A
name: Shishehbor, Mehdi H
name: Al-Kindi, Sadeer
name: Zidar, David A
Publisher: name: SAGE Journals
Year: 2023
Subjects: Cardiology
Surgery

description: Supplemental material, sj-pdf-4-vmj-10.1177_1358863X231169323 for Immunologic profiles in patients with chronic limb-threatening ischemia undergoing endovascular revascularization by Jun Li, Shilpkumar Arora, Heather Wheat, Siddhartha Dash, Stephen Kimura, Justin Smith, Yulanka Castro-Dominguez, Clint Oommen, Tarek A Hammad, Mehdi H Shishehbor, Sadeer Al-Kindi and David A Zidar in Vascular Medicine
title: Der Teufel als Verführer - zum Guten?
Creators: name: Stampf, Christina
Year: 2009

description: „Der Teufel als Verführer – zum Guten? Eine filmanalytische Untersuchung der Teufelsfigur und ihrer Beziehung zur verführten Person auf der Suche nach positiven Aspekten anhand ausgewählter Beispiele“ Ziel dieser Untersuchung ist es durch eine hermeneutisch-interpretative Analyse auf Basis kulturhistorischer und filmwissenschaftlicher Theorien mit Hilfe ausgewählter methodischer Verfahren positiven Aspekten der filmischen Teufelsfigur nachzugehen. Der Fokus liegt dabei auf der Analyse der Teufelsfigur in Verführergestalt, deren Beziehung und Interaktion zur erwählten Person und der Annahme einer läuternden, entwicklungsfördernden Funktion. Der theoretische Teil, der sich konkret mit dem kulturhistorischen Teufel befasst, wurde einem umfassenden Angebot an Auslegungen theologischer, soziologischer, psychologischer und philosophischer Teufelsbeschreibungen entnommen. Dem stereotypen, klischeehaften Bild des Teufels, das sich aus christlich-mittelalterlichen Werten und Vorstellungen konstituiert und als Schreckensfigur manifestiert, wird ein alternatives Weltbild entgegengestellt, in dem der Teufel als Bestandteil der Schöpfung und notwendiges, aktiv vorantreibendes Element integriert wird. Zur Analyse wurden psychologische Interpretationen (als „Schatten“), literarische Referenzen (Goethes und Miltons Darstellungen) und mythologische Implikationen herangezogen. Weiters fundieren eine genretheoretische Einordnung und filmdramaturgische Begrifflichkeiten bis hin zu mythologischen Betrachtungen den Teufelsfilm im Rahmen einer filmwissenschaftlichen und kultursoziologischen Betrachtung. Das methodische Vorgehen erfolgt anhand von Inhaltsangabe, Sequenzprotokoll und selbst erstellten Zeitachsen zu den Filmen nach der „Systematischen Filmanalyse“ von Helmut Korte sowie anhand eines „Modelling“ der Hauptfiguren nach Brigitte Haselauer. Die Untersuchung und Argumentation vollzieht sich in drei Blöcken an forschungsleitenden Fragestellungen: Analyse der beiden Hauptfiguren, Analyse der Dramaturgie und anschließender Interpretation auf Basis der Läuterungshypothese. Zusammenfassend zeigen sich ambivalente Tendenzen sowohl in der Teufelsdarstellung wie auch in der Inszenierung der menschlichen Figur. Die Teufelsdarstellung stützt sich auf mittelalterlich-christliche Symbolik (wie beispielsweise den Pakt), differenzierte Tendenzen sind jedoch in Ansätzen lesbar. Seiner erwählten Person haftet ein Mangel an, der durch den Teufel zur Entwicklung gebracht und beseitigt wird. Der Teufel steuert den Entwicklungsprozess, wobei der freie Wille gegeben ist. Letztendlich haben die Interventionen des Teufels Positives in Leben und Charakter des Hauptprotagonisten bewirkt. Seine Rolle im Weltbild schwankt zwischen Rebellion und mephistophelischer Bewusstseinserweiterung. Beide Darstellungen definieren eine Moral, die gegen materielle, kapitalistische oder egoistische Werte gerichtet ist und polemisieren für eine altruistische, integrative Lebensführung.
Differential requirement of Vav proteins for Btk-dependent and –independent signaling during B Cell development
Creators: name: Betzler, Annika C.
name: Kieser, Sebastian Karl
name: Fiedler, Katja
name: Laban, Simon Andreas
name: Theodoraki, Marie-Nicole
name: Schuler, Patrick
name: Wirth, Thomas
name: Tedford, Kerry
name: Fischer, Klaus-Dieter
name: Hoffmann, Thomas K.
name: Brunner, Cornelia
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: BTK
subject: Bruton’s tyrosine kinase
subject: VAV
subject: B cell development
subject: Secondary lymphoid organs
subject: Ca2+ signaling
subject: DDC 610 / Medicine & health
subject: Agammaglobulinaemia Tyrosine Kinase
subject: Calcium signaling
subject: B-lymphocytes
subject: Protein-Tyrosin-Kinasen
subject: B-Lymphozyt

description: Btk and Vav proteins are all components of the signalosome that builds upon B cell receptor (BCR) activation. However, the role of Vav proteins within the signalosome is quite complex and not yet fully understood. Until now, studies of these have focused predominantly on a deficiency of Vav proteins alone or in combination with other Vav protein family members. Since a physical association of Btk with Vav was shown previously, we asked whether these molecules lie in the same or independent signaling pathways. By analyzing Vav1 and Vav3 single knock-out mice and generating double-knock-out animals deficient for either Vav1 or Vav3 and Btk, we observed, in line with previous publications, no severe B cell developmental defects when either Vav1 or Vav3 alone are not expressed. However, a simultaneous deficiency of Btk together with either Vav1 or Vav3 leads to a severe reduction of splenic B cells, which exhibit an immature phenotype. B cell developmental defects of Btk/Vav1-double deficient mice in the periphery were more severe than those observed in Btk-single-deficient animals. Additionally, morphological changes in splenic microarchitecture were observed in double- but also in single-knock-out mutants. These observations were accompanied by reduced BCR-induced Ca2+ mobilization, proliferation, germinal center formation and immunoglobulin secretion. Although deletion of Btk alone impaired Ca2+ mobilization upon BCR activation, the defect was even more severe when Vav1 or Vav3 were also mutated, indicating that Btk and the Vav proteins act in separate pathways that converge on Ca2+ signaling. In vitro ASC differentiation suggests that both B and T cells contribute to the observed phenotype of a Btk/Vav-double deficiency. Our results show that Vav proteins and Btk are both components of the BCR-activated signalosome but control separate signaling pathways important for B cell development.
Additional file 1 of The Clinical Teaching Fellow role: exploring expectations and experiences
Creators: name: Harris, Isobel Marion
name: McNeilly, Heather
name: Ward, Derek J.
name: Sitch, Alice J.
name: Parry, Jayne
name: Greenfield, Sheila
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1.
The Linear Arrangement Library. A new tool for research on syntactic dependency structures
Creators: name: Alemany-Puig, Lluís
name: Esteban, Juan Luis
name: Ferrer-i-Cancho, Ramon
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computation and Language (cs.CL)
subject: Discrete Mathematics (cs.DM)
subject: FOS: Computer and information sciences

description: The new and growing field of Quantitative Dependency Syntax has emerged at the crossroads between Dependency Syntax and Quantitative Linguistics. One of the main concerns in this field is the statistical patterns of syntactic dependency structures. These structures, grouped in treebanks, are the source for statistical analyses in these and related areas; dozens of scores devised over the years are the tools of a new industry to search for patterns and perform other sorts of analyses. The plethora of such metrics and their increasing complexity require sharing the source code of the programs used to perform such analyses. However, such code is not often shared with the scientific community or is tested following unknown standards. Here we present a new open-source tool, the Linear Arrangement Library (LAL), which caters to the needs of, especially, inexperienced programmers. This tool enables the calculation of these metrics on single syntactic dependency structures, treebanks, and collection of treebanks, grounded on ease of use and yet with great flexibility. LAL has been designed to be efficient, easy to use (while satisfying the needs of all levels of programming expertise), reliable (thanks to thorough testing), and to unite research from different traditions, geographic areas, and research fields.
Building Blocks of a Flip-Chip Integrated Superconducting Quantum Processor
Creators: name: Kosen, Sandoko
name: Li, Hang-Xi
name: Rommel, Marcus
name: Shiri, Daryoush
name: Warren, Christopher
name: Grönberg, Leif
name: Salonen, Jaakko
name: Abad, Tahereh
name: Biznárová, Janka
name: Caputo, Marco
name: Chen, Liangyu
name: Grigoras, Kestutis
name: Johansson, Göran
name: Kockum, Anton Frisk
name: Križan, Christian
name: Lozano, Daniel Pérez
name: Norris, Graham
name: Osman, Amr
name: Fernández-Pendás, Jorge
name: Ronzani, Alberto
name: Roudsari, Anita Fadavi
name: Simbierowicz, Slawomir
name: Tancredi, Giovanna
name: Wallraff, Andreas
name: Eichler, Christopher
name: Govenius, Joonas
name: Bylander, Jonas
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We have integrated single and coupled superconducting transmon qubits into flip-chip modules. Each module consists of two chips -- one quantum chip and one control chip -- that are bump-bonded together. We demonstrate time-averaged coherence times exceeding $90\,μs$, single-qubit gate fidelities exceeding $99.9\%$, and two-qubit gate fidelities above $98.6\%$. We also present device design methods and discuss the sensitivity of device parameters to variation in interchip spacing. Notably, the additional flip-chip fabrication steps do not degrade the qubit performance compared to our baseline state-of-the-art in single-chip, planar circuits. This integration technique can be extended to the realisation of quantum processors accommodating hundreds of qubits in one module as it offers adequate input/output wiring access to all qubits and couplers.
description: 33 pages, 12 figures, includes supplementary materials, updated with further calculations on participation ratio and Purcell limit
Coherent multistatic MIMO radar networks based on repeater tags
Creators: name: Meinecke, Benedikt
name: Steiner, Maximilian
name: Schlichenmaier, Johannes
name: Hasch, Jürgen
name: Waldschmidt, Christian
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Direction-of-arrival estimation
subject: Repeater
subject: DDC 620 / Engineering & allied operations
subject: Bistatic radar
subject: Coherent radar
subject: Compressed sensing (Telecommunication)
subject: MIMO systems
subject: Electric networks
subject: Radar transmitters
subject: Radar
subject: Detectors
subject: Signal processing
subject: Bistatisches Radar
subject: Passives Radar
subject: Komprimierte Abtastung
subject: MIMO
subject: Elektrisches Netzwerk
subject: Transceiver
subject: Radar
subject: Induktiver Sensor
subject: Signalverarbeitung

description: In this paper, a coherent multistatic radar network with a novel system architecture is presented, which circumvents the general problems of clock distribution and phase noise related signal-to-noise ratio (SNR) issues. The proposed network consists of a variable number of multiple-input multiple-output (MIMO) radar sensors and a variable number of repeater tags, all of which operate incoherently on the hardware level. In a minimum configuration, the network only consists of one MIMO radar sensor and a repeater tag. The theory behind such a multistatic network is mathematically derived and simulations are presented to show key aspects of the network, i.e. multistatic range and Doppler measurements as well as high resolution angle estimation exploiting a very large virtual aperture spanning the whole network. Measurements with one sensor and one repeater tag at 77 GHz are carried out to verify the simulations. The measurements show that the bistatic path between the sensor and repeater tag retains coherency.
Additional file 2 of The Clinical Teaching Fellow role: exploring expectations and experiences
Creators: name: Harris, Isobel Marion
name: McNeilly, Heather
name: Ward, Derek J.
name: Sitch, Alice J.
name: Parry, Jayne
name: Greenfield, Sheila
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Supplementary Material 2.
title: Betteln in Österreich
Creators: name: Koller, Ferdinand Eduard
Year: 2009

description: Wie geht die österreichische Gesellschaft mit bettelnden Menschen um? Diese Frage wird auf der Ebene des öffentlichen Diskurses und der Ebene von gesetzlichen Maßnahmen (Bettelverbote) untersucht. Aus der Perspektive der theologischen Ethik wird die aktuelle Situation beurteilt, das Betteln als Grundrecht dargestellt und – angesichts der größtenteils restriktiven Maßnahmen – die Frage nach einem aus christlicher Sicht verantwortbaren Umgang mit bettelnden Menschen gestellt. Dabei wird einerseits die Frage geklärt, ob an bettelnde Menschen Geld gespendet werden soll, andererseits sollen Kriterien für solidarisches Handeln mögliche Wege einer Neuorientierung im Umgang mit bettelnden Menschen aufzeigen.
Additional file 1 of Gut microbiota dynamics and fecal SCFAs after colonoscopy: accelerating microbiome stabilization by Clostridium butyricum
Creators: name: Chen, Zhenhui
name: Yu, Lu
name: Liu, Jiaxin
name: Kong, Jingjing
name: Deng, Xiaoshi
name: Guo, Xiaotong
name: Shan, Jiamin
name: Zhou, Daixuan
name: Li, Wendan
name: Lin, Yangfan
name: Huang, Wanwen
name: Zeng, Weisen
name: Shi, Xinlong
name: Bai, Yang
name: Fan, Hongying
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Chemical Sciences not elsewhere classified
subject: Ecology

description: Additional file 1: Figure S1. Faecal samples and intestinal contents were collected from 11 subjects at 8 time points before, during and 60 days after colonoscopy. NA denotes an incurred sample loss. Figure S2. The ratio of Firmicutes and Bacteroidetes showed the longitudinal fluctuation patterns of gut microbiota in the Control group. **p < 0.01. Figure S3. Quantity of buks containing bacteria stains at the phylum level. Figure S4. The ratio of Firmicutes and Bacteroidetes showed the longitudinal fluctuation patterns of gut microbiota in the Clostridium Butyricum group. **p < 0.01.
Yield—not only lifetime—of the photoinduced charge‐separated state in iridium complex–polyoxometalate dyads impact their hydrogen evolution reactivity
Creators: name: Luo, Yusen
name: Maloul, Salam
name: Schönweiz, Stefanie
name: Wächtler, Maria
name: Streb, Carsten
name: Dietzek, Benjamin
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: catalytic mechanisms
subject: photophysics
subject: DDC 540 / Chemistry & allied sciences
subject: Hydrogen evolution reaction
subject: Photochemistry
subject: Polyoxometalates
subject: Fotochemie
subject: Fotophysik
subject: Polyoxometallate

description: A mechanistic study on the distinct hydrogen evolution reactivity (HER) of three cyclometalated IrIII complex–polyoxometalate (Ir‐POMM) dyads. Their HER activity was tuned by modifying the central metal ion M of the POMM. The lifetime or the yield of Ir.+‐POMM.− determined the different HER activity of Ir‐POMM (see figure). Covalently linked photosensitizer–polyoxometalate (PS‐POM) dyads are promising molecular systems for light‐induced energy conversion processes, such as “solar” hydrogen generation. To date, very little is known of their fundamental photophysical properties which affect the catalytic reactivity and stability of the systems. PS‐POM dyads often feature short‐lived photoinduced charge‐separated states, and the lifetimes of these states are considered crucial for the function of PS‐POM dyads in molecular photocatalysis. Hence, strategies have been developed to extend the lifetimes of the photoinduced charge‐separated states, either by tuning the PS photophysics or by tuning the POM redox properties. Recently, some of us reported PS‐POM dyads based on cyclometalated IrIII complexes covalently linked to Anderson‐type polyoxometalate. Distinct hydrogen evolution reactivity (HER) of the dyads was observed, which was tuned by varying the central metal ion M of the POMM (M=Mn3+, Co3+, Fe3+). In this manuscript, the photoinduced electron‐transfer processes in the three Ir‐POMM dyads are investigated to rationalize the underlying reasons for the differences in HER activity observed. We report that upon excitation of the IrIII complex, ultrafast (sub‐ps) charge separation occurs, leading to different amounts of the charge‐separated states (Ir.+‐POMM.−) generated in the different dyads. However, in all dyads studied, the resulting Ir.+‐POMM.− species are short‐lived (sub‐ns) when compared to reference electron acceptors (e.g. porphyrins or fullerenes) reported in the literature. The reductive quenching of Ir.+‐POMM.− by a sacrificial donor, triethyl amine (1 m), to generate the intermediate Ir‐POMM.− is estimated to be very efficient (70–80 %) for all dyads studied. Based on this analyses, we conclude that the yield instead of the lifetime of the Ir.+‐POMM.− charge‐separated state determines the catalytic capacity of the dyads investigated. This new feature in the PS‐POM photophysics could lead to new design criteria for the development of novel PS‐POM dyads.