cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Selbstbestimmung kontrovers?! Patient*innenautonomie in der Geburtshilfe
Creators: name: Eckardt, Sarah
Publisher: name: Humboldt-Universität zu Berlin
Year: 2020
Subjects: subject: Autonomie
subject: Care
subject: Geburt
subject: Gesundheit
subject: Reproduktion
subject: Selbstbestimmung
subject: ddc:303

description: Selbstbestimmung und Autonomie während der Geburt sind seit den 1970er-Jahren zentrale Forderungen der Frauengesundheits- und Patient*innenbewegungen. Im Fokus steht dabei eine Emanzipation von der bio-medizinischen Geburtsmedizin mit ihren starken Interventionen und Kontrollpraktiken. Bei Selbstbestimmung im herkömmlichen Sinn wird ein autonomes, unabhängiges Subjekt vorausgesetzt und adressiert. Aber passt diese Beschreibung überhaupt zu einem Ereignis wie der Geburt? Oder treten angesichts der Spannungslage zwischen Selbstbestimmung und Fürsorge Grenzen der Selbstbestimmung für Gebärende zutage? Diesen Fragen geht der Artikel nach, indem er zuerst einen medizinischen Paradigmenwechsel zum Themenbereich der Patient*innenautonomie nachzeichnet und danach fragt, inwiefern das Selbstbestimmungsparadigma für professionelle Geburtshelfer*innen und Gebärende praktisch relevant ist. Dazu wurden gebärende Frauen kurz vor und nach der Geburt befragt. Weiterführende Überlegungen zu Widerstand und Empowerment in einer sehr machtvollen Institution wie dem Krankenhaus, in dem ein Großteil der Geburten stattfindet, bilden den Abschluss des Artikels.
Additional file 1 of Sexual wellbeing in early adolescence: a cross-sectional assessment among girls and boys in urban Indonesia
Creators: name: Kågesten, Anna E.
name: Pinandari, Anggriyani Wahyu
name: Page, Anna
name: Wilopo, Siswanto Agus
name: van Reeuwijk, Miranda
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1: Appendix Table 1. Measures and operationalization of covariates. Appendix Table 2. Bivariate analysis of selected sexual wellbeing indicators: Boys (N = 2031). Appendix Table 3. Bivariate analysis of selected sexual wellbeing indicators: Girls (N = 2278).
Multi-peak solitons in nonlocal nonlinear system with sine-oscillation response
Creators: name: Zhong, Lanhua
name: Dang, Dalong
name: Li, Wei
name: Ren, Zhanmei
name: Guo, Qi
Publisher: name: arXiv
Year: 2021
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The multi-peak solitons and their stability are investigated for the nonlocal nonlinear system with the sine-oscillation response, including both the cases of positive and negative Kerr coefficients. The Hermite-Gaussian-type multi-peak solitons and the ranges of the degree of nonlocality within which the solitons exist are analytically obtained by the variational approach. This is the first time, to our knowledge at least, to discuss the solution existence range of the multi-peak solitons analytically, although approximately. The variational analytical results are confirmed by the numerical ones. The stability of the multi-peak solitons are addressed by the linear stability analysis. It is found that the upper thresholds of the peak-number of the stable solitons are five and four for the system with negative and positive Kerr coefficients, respectively.
2,4,6-Trimethoxy chalcone derivatives: an integrated study for redesigning novel chemical entities as anticancer agents through QSAR, molecular docking, ADMET prediction, and computational simulation
Creators: name: Chitre, Trupti S.
name: Mandot, Aayush M.
name: Bhagwat, Ramali D.
name: Londhe, Nikhil D.
name: Suryawanshi, Atharva R.
name: Hirode, Purvaj V.
name: Bhatambrekar, Aniket L.
name: Choudhari, Somdutta Y.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: QSAR, an efficient and successful approach for optimizing lead compounds in drug design, was employed to study a reported series of compounds derived from 2,4,6-trimethoxy chalcone derivatives. The ability of these compounds to inhibit CDK1 was examined, with the help of QSARINS software for model development. The generated QSAR model revealed three significant descriptors, exhibiting strong correlations with impressive statistical values: cross-validation leave-one-out correlation coefficient (Q2LOO) = 0.6663, coefficient of determination (R2) = 0.7863, external validation coefficient (R2ext) = 0.7854, cross-validation leave-many-out correlation coefficient (Q2LMO) = 0.6256, Concordance Correlation Coefficient for cross-validation (CCCcv) = 0.8150, CCCtr = 0.8804, and CCCext = 0.8750. From the key structural findings and the insights gained from the descriptors, ETA_dPsi_A, WTPT-5, and GATS7s, new lead molecules were designed. The designed molecules were then evaluated for their CDK1 inhibitory activity using the three-descriptor model developed in this study. To evaluate their drug likeliness, in-silico ADMET predictions were made using Schrodinger’s Software. Molecular docking was carried out to determine the interactions of designed compounds with the target protein. The designed compounds having excellent binding pocket molecular stability and anticancer effectiveness was substantiated by the findings of the molecular dynamics simulation. The results of this work point out important properties and crucial interactions necessary for efficient protein inhibition, suggesting lead candidates for further development as novel anticancer agents.
Geometrical constraints on dark energy models
Creators: name: Lazkoz, Ruth
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: This contribution intends to give a pedagogical introduction to the topic of dark energy (the mysterious agent supposed to drive the observed late time acceleration of the Universe) and to various observational tests which require only assumptions on the geometry of the Universe. Those tests are the supernovae luminosity, the CMB shift, the direct Hubble data, and the baryon acoustic oscillations test. An historical overview of Cosmology is followed by some generalities on FRW spacetimes (the best large-scale description of the Universe), and then the test themselves are discussed. A convenient section on statistical inference is included as well.
description: 28 pages, 15 pages, lecture notes prepared for the ``Advanced Summer School in Physics 2007" organized by Cinvestav (Mexico DF)
title: A Chandra Catalog of X-Ray Sources in the Central 150 pc of the Galaxy
Creators: name: Muno, MP
name: Bauer, FE
name: Bandyopadhyay, RM
name: Wang, QD
Publisher: name: University of Massachusetts Amherst
Year: 2006
Subjects: subject: Astrophysics and Astronomy

description: This is the pre-published version harvested from ArXiv. The published version is located at http://iopscience.iop.org/0067-0049/165/1/173/
description: We present the catalog of X-ray sources detected in a shallow Chandra survey of the inner 2° × 08 of the Galaxy and in two deeper observations of the Radio Arches and Sgr B2. The catalog contains 1352 objects that are highly absorbed (NH 4 × 1022 cm-2) and are therefore likely to lie near the Galactic center (D 8 kpc), and 549 less absorbed sources that lie within 6 kpc of Earth. On the basis of the inferred luminosities of the X-ray sources and the expected numbers of various classes of objects, we suggest that the sources with LX 1033 ergs s-1 that comprise 90% of the catalog are cataclysmic variables and that the 100 brighter objects are accreting neutron stars and black holes, young isolated pulsars, and Wolf-Rayet and O (WR/O) stars in colliding-wind binaries. We find that the spatial distribution of X-ray sources matches that of the old stellar population observed in the infrared, which supports our suggestion that most of the X-ray sources are old cataclysmic variables. However, we find that there is an apparent excess of 10 bright sources in the Radio Arches region. That region is already known to be the site of recent star formation, so we suggest that the bright sources in this region are young high-mass X-ray binaries, pulsars, or WR/O star binaries. We briefly discuss some astrophysical questions that this catalog can be used to address.
A Corrective Meta-Analysis of Personalized Normative Feedback
Creators: name: Zimmerman, David
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 170202 Decision Making
subject: FOS: Psychology

description: Personalized Normative Feedback (PNF) has been proposed as an inexpensive, scalable intervention for reducing problematic consumption of alcohol, particularly among college students. Many individual studies, as well as meta-analyses, have tested the efficacy of PNF. The findings have been generally positive, demonstrating that it decreases alcohol consumption and the problems associated with excessive consumption. Unfortunately, many of these studies have less than ideal methodologies, which potentially introduce bias to their results. We apply a quantitative adjustment procedure to the findings of each study to account for these biases. Results were divided by a factor of 1.61 on average. While many of the results remain statistically significant after correction, the effects are relatively small, less than 0.2 (Cohen’s d), in all. Other methods will need to be developed if PNF is to achieve dramatic progress towards reducing drinking. Little evidence exists on the long-term impacts of PNF, or how PNF interacts with the transition out of college.
Triagem virtual de imagens de imuno-histoquímica usando redes neurais artificiais e espectro de padrões
Creators: name: Lima, Higor Neto
name: Santos, Wellington Pinheiro dos
name: Valença, Mêuser Jorge Silva
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Neural and Evolutionary Computing (cs.NE)
subject: Image and Video Processing (eess.IV)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The importance of organizing medical images according to their nature, application and relevance is increasing. Furhermore, a previous selection of medical images can be useful to accelerate the task of analysis by pathologists. Herein this work we propose an image classifier to integrate a CBIR (Content-Based Image Retrieval) selection system. This classifier is based on pattern spectra and neural networks. Feature selection is performed using pattern spectra and principal component analysis, whilst image classification is based on multilayer perceptrons and a composition of self-organizing maps and learning vector quantization. These methods were applied for content selection of immunohistochemical images of placenta and newdeads lungs. Results demonstrated that this approach can reach reasonable classification performance.
description: in Portuguese
Additional file 1 of Remnant cholesterol is correlated with retinal vascular morphology and diabetic retinopathy in type 2 diabetes mellitus: a cross-sectional study
Creators: name: Chen, Shuli
name: Xu, Yi
name: Chen, Bo
name: Lin, Senlin
name: Lu, Lina
name: Cheng, Minna
name: Wang, Yuheng
name: Yang, Qinping
name: Ling, Saiguang
name: Zhou, Dengji
name: Shi, Yan
name: Zou, Haidong
name: Ma, Yingyan
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Virology

description: Additional file 1: Fig. S1 Subgroup analyses for correlation between RC and CRAE. Fig. S2 Subgroup analyses for correlation between RC and CRVE. Fig. S3 Subgroup analyses for correlation between RC and Df. Table S1. Binary logistic regression analyses for correlation between retinal vasculature and DR.
title: Proactive versus Reactive Sexual and Reproductive Health Rights: A Comparative Case Study Analysis of Morocco and Tunisia
Creators: name: Feather, Ginger
Publisher: name: Humboldt-Universität zu Berlin
Year: 2020
Subjects: subject: Islam
subject: Kriminalisierung
subject: reproduktive Rechte
subject: Schwangerschaft
subject: Schwangerschaftsabbruch
subject: sexual and reproductive health rights
subject: ddc:303

description: Morocco and Tunisia, two progressive Muslim-majority countries, took vastly different approaches to women’s sexual and reproductive health rights (SRHR). Sharing a French colonial past and Maliki Islamic tradition, Tunisia is an emerging democracy with a long history of top-down women’s rights advances and state-promoted SRHR. Tunisian women have benefitted from SRH education, access to contraception, emergency contraception, and state-funded first trimester abortion. Tunisia targets vulnerable populations, including unmarried, minor, rural, and poor women, with special clinics and subsidies. Finally, Tunisia holds men responsible for children they father outside of wedlock. In contrast, Morocco’s bottom-up feminist-driven approach to SRHR, including access to contraception, emergency contraception, and abortion, is circumscribed and exclusionary, targeting married couples. The criminalization of extramarital sexual relations and most abortions force single women with unwanted pregnancies to resort to unsafe abortion. Moroccan men who father children outside of marriage enjoy legal impunity from paternal responsibilities. Nevertheless, the recent rise of Islamic parties in both countries poses a potential threat to Tunisia’s proactive laws and policies governing SRHR, while adding another obstacle to adequate SRHR provision in Morocco.
Chiral Symmetry Restoration at Finite Temperature in the Linear Sigma--Model
Creators: name: Metzger, D.
name: Meyer--Ortmanns, H.
name: Pirner, H. --J.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The temperature behaviour of meson condensates $$ and $$ is calculated in the $SU(3)\times SU(3)$-linear sigma model. The couplings of the Lagrangian are fitted to the physical $π,K,η,η'$ masses, the pion decay constant and a $O^+(I=0)$ scalar mass of $m_σ=1.5$ GeV. The quartic terms of the mesonic interaction are converted to a quadratic term with the help of a Hubbard-Stratonovich transformation. Effective mass terms are generated this way, which are treated self-consistently to leading order of a $1/N$-expansion. We calculate the light $$ and strange $$-quark condensates using PCAC relations between the meson masses and condensates. For a cut-off value of 1.5 GeV we find a first-order chiral transition at a critical temperature $T_c\sim 161$ MeV. At this temperature the spontaneously broken subgroup $SU(2)\times SU(2)$ is restored. Entropy density, energy density and pressure are calculated for temperatures up to and slightly above the critical temperature. To our surprise we find some indications for a reduced contribution from strange mesons for $T\geq T_c$.
description: 17 pages, HD--TVP--93--15. (3 figures - available on request)
title: AN, Registre des écrous du Châtelet, Y5266, f. p1000945
Creators: name: Claustre, Julie
name: Nationales, Archives
name: Archives Nationales
name: Claustre, Julie
name: ArchivesNationales/J.CLAUSTRE/H.REGAZZI/2020
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Châtelet
subject: registre
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Registre des écrous du Châtelet, Archives Nationales, Y5266. Numérisation en mode image.
description: Bibliographic citation: Archives Nationales, Registre des écrous du Châtelet, Y5266, f. p1000945
Financial Markets and the Phase Transition between Water and Steam
Creators: name: Schmidhuber, Christof
Publisher: name: arXiv
Year: 2021
Subjects: subject: Statistical Finance (q-fin.ST)
subject: High Energy Physics - Theory (hep-th)
subject: Cellular Automata and Lattice Gases (nlin.CG)
subject: Physics and Society (physics.soc-ph)
subject: General Finance (q-fin.GN)
subject: FOS: Economics and business
subject: FOS: Physical sciences

description: Motivated by empirical observations on the interplay of trends and reversion, a lattice gas model of financial markets is presented. The shares of an asset are modeled by gas molecules that are distributed across a hidden social network of investors. The model is equivalent to the Ising model on this network, whose magnetization represents the deviation of the asset price from its value. Moreover, the system should drive itself to its critical temperature in efficient markets. There, it is characterized by universal critical exponents, in analogy with the second-order phase transition between water and steam. These critical exponents imply predictions for the auto-correlations of financial market returns and for Hurst exponents. For a simple network topology, consistency with empirical observations implies a fractal network dimension near 3, and a correlation time at least as long as the economic cyle. To also explain the observed market auto-correlations at intermediate scales, the model should be extended beyond the critical domain, to other network topologies, and to other models of critical dynamics.
description: 34 pages, 7 figures, significantly revised section 4, added predictions for Hurst exponents
“You Have Made A Mess of Your Life Up to Date”: Talking to Girls in Juvenile Court in Post-World War I Los Angeles
Creators: name: Smith-Bernstein, Isabel
Publisher: name: Carnegie Mellon University
Year: 2013
Subjects: History

description: This thesis analyzes juvenile court hearing transcripts from original case files of the Los Angeles Juvenile Court in 1920, paying special attention to cases involving a famous juvenile court “referee” (i.e., judge,) Miriam Van Waters. The 1920s was a particularly interesting time for adolescent girls, as industrialization led to increased personal freedom and the development of an active nightlife for youth. Adults were still very invested in maintaining traditional standards of morality for their daughters, however, and moral breaches were generally what girls were brought into juvenile court for: sex, curfew violation, disobeying guardians, etc. Van Waters would delve into the girls’ family life, psyche and aspirations in order to decide on a suitable place for the girl to be sent or whether to supervise the girl in her own home, on probation. My research focuses particularly on the transcripts of conversations between Van Waters, the girls, and her parents in order to understand how juvenile courts decided what to do with “delinquent” girls in the post-World War I period.
Side-gated transport in FIB-fabricated multilayered graphene nanoribbons
Creators: name: Dayen, Jean-Francois
name: Mahmood, Ather
name: Golubev, Dmitry S.
name: Roch-Jeune, Isabelle
name: Salles, Philippe
name: Dujardin, Erik
Publisher: name: arXiv
Year: 2007
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: In this Letter, we present the patterning, exfoliation and micromanipulation of thin graphitic discs which are subsequently connected and patterned into sub-100nm wide ribbons with a resist-free process using Focused Ion Beam (FIB) lithography and deposition. The electronic transport properties of the double side-gated nanoribbons are then investigated down to 40 K and interpreted with a simple model of 1D array of tunnelling junctions.
description: Revised version: more detailed description of control experiments. 5 pages, 4 figures, submitted to Small (Wiley-VCH). Added supporting information (Figs S1 to S8)
title: Libra : insights into its expected stability
Creators: name: Groß, Jonas
name: Leon, Landes
Publisher: name: University of Bayreuth
Year: 2019
Subjects: subject: Cryptocurrency, Currency Regime, Libra
subject: 330

description: Recently, stablecoins have gained high public attention. They provide a value-stable alternative to cryptocurrencies such as Bitcoin or Ethereum, which are volatile and, therefore, not suitable as means of payment. The announcement of the Libra project has further increased the public interest in stablecoins. In this paper, we study whether Libra might fulfill the function of money. We argue that Libra can only act as a proper unit of account and store of value if its value is relatively stable. To analyze the expected stability of Libra, we use the Special Drawing Rights as a proxy. For this purpose, we calculate common risk measures, namely, standard deviation, Value-at-Risk, and Maximum Drawdown. We show that Libra’s exchange rate against strong currencies in industrialized countries can be expected to be relatively stable in the long-term, however fluctuating in the short-term. In emerging and developing countries, Libra can offer protection against the devaluation of local currencies. However, holding Libra will also entail a higher risk of loss for residents of these countries. Furthermore, we find from current stablecoins, as Tether or TrueUSD, that Libra will not necessarily be traded at par with the underlying reserves any time. Reasons for this divergence can be a perceived risk of default and incentives to carry out hedging transactions.
Sensitive multiplex spectroscopy in the molecular fingerprint 2.4 $μ$m region with a Cr^{2+}:ZnSe femtosecond laser
Creators: name: Sorokin, Evgeni
name: Sorokina, Irina T.
name: Mandon, Julien
name: Guelachvili, Guy
name: Picqué, Nathalie
Publisher: name: arXiv
Year: 2007
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: An ultrashort-pulse Cr^{2+}:ZnSe laser is a novel broadband source for sensitive high resolution molecular spectroscopy. A 130-fs pulse allows covering of up to 380 cm^-1 spectral domain around 2.4 $μ$m which is analyzed simultaneously with a 0.12 cm^-1 (3.6 GHz) resolution by a Fourier-transform spectrometer. Recorded in 13 s, from 70-cm length absorption around 4150 cm^-1, acetylene and ammonia spectra exhibit a 3800 signal-to-noise ratio and a 2.4*10^-7 cm^-1*Hz^-1/2 noise equivalent absorption coefficient at one second averaging per spectral element, suggesting a 0.2 ppbv detection level for HF molecule. With the widely practiced classical tungsten lamp source instead of the laser, identical spectra would have taken more than one hour.
description: Optics express in press (2007) in press
“Something About the Way You Look Tonight”: Popular Music Festivals as Rites of Passage in the Contemporary United States
Creators: name: Jackson, Geneva
Publisher: name: Carnegie Mellon University
Year: 2016
Subjects: History

description: Music festivals comprise a wide but specific set of experiences, the good lumped with the bad, and the insignificant mingling with the impactful. The people who attend them come from diverse backgrounds, locations, and age groups. Nevertheless, music festivals have grown to be a widespread cultural phenomenon in the United States. In recent years the festival industry has experienced a boom in popularity, with events of all sizes cropping up across the country. Viewed as a microcosm, an examination of the temporary world of a festival gives insight into larger cultural trends and values. The following thesis seeks to unpack the music festival as an experience in an effort to determine significant elements and to analyze better the important role these festivals play in modern American culture
A theory on skyrmion size and profile
Creators: name: Wang, X. S.
name: Yuan, H. Y.
name: Wang, X. R.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A magnetic skyrmion is a topological object consisting of an inner domain, an outer domain, and a wall that separates the two domains. The skyrmion size and wall width are two fundamental quantities of a skyrmion that depend sensitively on material parameters such as exchange energy, magnetic anisotropy, Dzyaloshinskii-Moriya interaction, and magnetic field. However, there is no quantitative understanding of the two quantities so far. Here, we present general expressions for the skyrmion size and wall width obtained from energy considerations. The two formulas agree almost perfectly with simulations and experiments for a wide range of parameters, including all existing materials that support skyrmions. Furthermore, it is found that skyrmion profiles agree very well with the Walker-like 360\textdegree{} domain wall formula.
description: 2 figures, 3 supplementary figures
Molecular docking, molecular dynamics, MM/PBSA approaches and bioactivity studies of nepetanudoside B isolated from endemic Nepeta aristata
Creators: name: Başar, Yunus
name: Demirtaş, İbrahim
name: Yenigün, Semiha
name: İpek, Yaşar
name: Özen, Tevfik
name: Behçet, Lütfi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Nepetanudoside B (NNB) was isolated from aerial parts of endemic Nepeta aristata crude extract (CH3OH-CHCl3) using silica gel (n-hexane, methanol, ethyl acetate, and dichlorometane, respectively) and sephadex LH-20 (65% Methanol-35% Chloroform) column chromatographies. Preparative-HPLC was used to purify NNB after activity-guided isolation of methanol sub-fractions with enzyme inhibitory and DNA protective properties. The NNB was determined using 1H,13C, COSY, HSQC, HMBC, and LC-MS/MS. The study compared the effects of NNB with conventional drugs in terms of its ability to inhibit enzymes such as urease, α-amylase, carbonic anhydrase (CA), lipase, α-glucosidase, and tyrosinase, as well as its ability to protect DNA. Enzyme kinetic and molecular docking were also used to evaluate this. NNB exhibited the best inhibitory activity on urease (1.28 ± 0.00 µg/mL), lipase (5.83 ± 0.10 µg/mL), BChE (3.73 ± 0.46 µg/mL), tyrosinase (7.39 ± 0.00 µg/mL), α-glucosidase (10.95 ± 0.00 µg/mL), α-amylase (22.11 ± 1.03 µg/mL) and AChE (25.68 ± 3.32 µg/mL), respectively. NNB has higher MolDock scores with binding energy in α-glucosidase (-233) and BChE (-8.90 kcal/mol). In enzyme kinetics studies, it was determined that urease, AChE, α-glucosidase, lipase, and CA were non-competitive , while BChE and tyrosinase were competitive inhibition mechanisms. Their Ki values were calculated as 0.09, 0.24, 0.09, 0.10, 0.08, 0.05, and 0.07 mM, respectively. Molecular dynamics simulation studies were performed for the interactions of NNB-BChE with MM/PBSA binding free energey RMSD, RMSF, Rg, SASA, and also the number of hydrogen bonds was calculated. The suitability and effectiveness of NNB have been proven in the food and pharmaceutical industries. The NNB molecule may lead to development studies as a BChE inhibitor.
Correspondence between the physics of extremal black holes and that of stable heavy atomic nuclei
Creators: name: Kosyakov, B. P.
name: Popov, E. Yu.
name: Vronsky, M. A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Extremal black holes are immune of Hawking evaporation. On the other hand, some heavy atomic nuclei feature extraordinary stability to spontaneous transmutations changing their mass numbers. The fact that extremal black holes and stable nuclei share a common trait, that of defying spontaneous ejection of their constituents, suggests that a good part of nuclear physics is modelled on physics of extremal black holes through a simple version of gauge/gravity duality. A general criterion for discriminating between stable and unstable microscopic systems can be formulated to gain a new insight into some imperfectly understood phenomena, such as instability of truly neutral spinless particles (Higgs bosons, $π_0$, quarkonia, glueballs).
description: 24 pages, 3 figures; v2: several typos fixed; v3: 16 pages; text shortened, results unchanged; v4: 17 pages; improved presentation; v5: 18 pages; minor improvement; v6 minor improvement
“All Bets Were Off”: Changes in Scientific Causation and Tort Law through the Lens of Agent Orange from 1984 to 2005
Creators: name: Albert, Kendra
Publisher: name: Carnegie Mellon University
Year: 2011
Subjects: History

description: Agent Orange, an herbicide used during the Vietnam War, occupies a unique place in the American psyche. On the one hand, the use of it and other similar herbicides and defoliants may have saved countless lives during the war, helping to protect American troops. On the other, Agent Orange contained highly toxic dioxin, a chemical that has been blamed for numerous medical problems among veterans, Vietnamese, and their families. The legal cases that have developed regarding Agent Orange balance a number of contentious issues, from the rights of former servicemen to sue the government to what kind of evidence is necessary to show that dioxin caused a disease.
Improved key process in representing Arctic warming (D3.5)
Creators: name: Davy, Richard
name: Gao, Yongqi
Publisher: name: Zenodo
Year: 2019

description: Summary: This Blue-Action task was focused on improving the representation of some of the most important
 physical processes which contribute to Arctic warming within the climate models used by the
 consortium. The two processes we addressed were the effect on the atmospheric state of the fracturing
 of the sea ice cover and turbulence under strongly stable thermal stratification. The creation and
 development of
 The work done: We first analysed the results of previously performed large eddy simulations which
 resolved the turbulence over leads to determine the effect leads have on sensible heat flux from open
 water. Because of the effect of three-dimensional structures in the turbulent mixing above leads, the
 heat flux coming from leads can be amplified compared to the fluxes one would get from open water
 under the same air-sea temperature difference. The amplification effect strongly depends on the width
 of the lead, with the largest effect occurring for leads of widths around 1.4 km. We assessed the
 functional sensitivity of this amplification effect to key parameters used in the turbulence-resolving
 model, including the length scale for the convective boundary layer, which reflects the background
 stability in the atmosphere.
 We combined this relation between the amplification effect of heat fluxes as a function of lead width
 with observed distributions of lead widths. These were taken from the peer-reviewed literature where
 The key findings: The presence of leads in sea ice dramatically alters the surface energy balance in the
 Arctic. There is a large seasonal cycle to the effect of the presence of leads, because the flux from the
 leads depends strongly on the background stability in the atmosphere. In the winter when the
 atmosphere is often strongly stably stratified, the leads strongly amplify the surface sensible heat flux
 coming from open water. In the summer there is the opposite effect and the generally weaker
 atmospheric stability reduces the flux coming from leads.
description: The Blue-Action project has received funding from the European Union's Horizon 2020 Research and Innovation Programme under Grant Agreement No 727852.
Chara antennata Grambast 1958
Creators: name: Sanjuan, Josep
name: Martín-Closas, Carles
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Plantae
Charophyta
Charophyceae
Charales
Characeae
Chara
Chara antennata

description: Chara aff. antennata Grambast, 1958 (Fig. 4 E-H)
Chara antennata Grambast, 1958: 188, fig. 79.
DISTRIBUTION. — Chara aff. antennata has previously been reported in Upper Eocene deposits from many European basins, i.e. Paris (Grambast 1958; Riveline 1986), Languedoc (Feist-Castel 1971), Provence (Feist-Castel 1977a) and Hampshire Basins (Feist- Castel 1977b; Riveline 1986). In the Ebro Basin, gyrogonites of Chara aff. antennata do not show any
evidence of fragmentation or erosion, suggesting that they were buried in situ or after short transport from the original locality. Ŋe sample was collected within a plastic yellowish marl horizon with abundant marine fauna, i.e. foraminifers and ostracods.Taphonomic and sedimentologic evidence, together with the abundance of shallow marine fauna, suggests that Chara aff. antennata grew in brackish water lagoons close to the shoreline.
DESCRIPTION
Gyrogonites small to medium, 350-620 µm high (mean 506 µm) and 235-335 µm wide (mean 304 µm), very elongate in shape, with a high isopolarity index ranging from 117 to 202 (mean 154). Spiral cells concave (about 48 µm wide). Ornamentation consists of irregularly shaped and spaced tubercles (very variable in size, ranging from 15-40 µm in diameter) arranged along the spiral cells. Eight to twelve (frequently nine to ten) convolutions are visible in lateral view. Apex psilocharoid and slightly convex. Base pointed with small pentagonal pore (about 35 µm across).
DISCUSSION
Ŋe width of gyrogonites from La Portelleta section (Sant Boi de Lluçanès) was about 75 µm smaller than the type population of Verzenay (France), resulting in a dominance of prolate to perprolate gyrogonite morphologies. Moreover, the specimens studied usually display smaller tubercles than the type population.
description: Published as part of Sanjuan, Josep & Martín-Closas, Carles, 2014, Taxonomy and palaeobiogeography of charophytes from the Upper Eocene- Lower Oligocene of the Eastern Ebro Basin (Catalonia, NE Spain), pp. 385-420 in Geodiversitas 36 (3) on pages 391-393, DOI: 10.5252/g2014n3a3, http://zenodo.org/record/4538531
Modality specific U-Net variants for biomedical image segmentation: A survey
Creators: name: Punn, Narinder Singh
name: Agarwal, Sonali
Publisher: name: arXiv
Year: 2021
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: With the advent of advancements in deep learning approaches, such as deep convolution neural network, residual neural network, adversarial network; U-Net architectures are most widely utilized in biomedical image segmentation to address the automation in identification and detection of the target regions or sub-regions. In recent studies, U-Net based approaches have illustrated state-of-the-art performance in different applications for the development of computer-aided diagnosis systems for early diagnosis and treatment of diseases such as brain tumor, lung cancer, alzheimer, breast cancer, etc., using various modalities. This article contributes in presenting the success of these approaches by describing the U-Net framework, followed by the comprehensive analysis of the U-Net variants by performing 1) inter-modality, and 2) intra-modality categorization to establish better insights into the associated challenges and solutions. Besides, this article also highlights the contribution of U-Net based frameworks in the ongoing pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) also known as COVID-19. Finally, the strengths and similarities of these U-Net variants are analysed along with the challenges involved in biomedical image segmentation to uncover promising future research directions in this area.
Avaliação do método dialético na quantização de imagens multiespectrais
Creators: name: Santos, Wellington Pinheiro dos
name: de Assis, Francisco Marcos
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Image and Video Processing (eess.IV)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The unsupervised classification has a very important role in the analysis of multispectral images, given its ability to assist the extraction of a priori knowledge of images. Algorithms like k-means and fuzzy c-means has long been used in this task. Computational Intelligence has proven to be an important field to assist in building classifiers optimized according to the quality of the grouping of classes and the evaluation of the quality of vector quantization. Several studies have shown that Philosophy, especially the Dialectical Method, has served as an important inspiration for the construction of new computational methods. This paper presents an evaluation of four methods based on the Dialectics: the Objective Dialectical Classifier and the Dialectical Optimization Method adapted to build a version of k-means with optimal quality indices; each of them is presented in two versions: a canonical version and another version obtained by applying the Principle of Maximum Entropy. These methods were compared to k-means, fuzzy c-means and Kohonen's self-organizing maps. The results showed that the methods based on Dialectics are robust to noise, and quantization can achieve results as good as those obtained with the Kohonen map, considered an optimal quantizer.
description: in Portuguese
The Effect of Water on Ionic Conductivity in Olivine
Creators: name: Fei, Hongzhan
name: Druzhbin, Dmitry
name: Katsura, Tomoo
Publisher: name: FID GEO
Year: 2020

description: High-temperature ionic conductivity in olivine single crystals has been measured in the [100], [010], and [001] crystallographic orientations as a function of pressure from 2 to 10 GPa, temperature from 1450 to 2180 K, and H2O content from 20 to 580 wt. ppm using multianvil presses with in situ impedance analyses. The experimental results yield an activation energy, activation volume, and H2O content exponent of 250–405 kJ/mol, 3.2–5.3 cm3/mol, and 1.3 ± 0.2, respectively, for the high-temperature ionic conduction regime. Olivine ionic conductivity has negative pressure and positive temperature dependences and is significantly enhanced by H2O incorporation. The [001] direction is more conductive than the [100] and [010] directions. The H2O-enhanced ionic conductivity may contribute significantly to the electrical conductivity profile in the asthenosphere, especially in the regions under relatively high-temperature and low-pressure conditions.
Right-handed-neutrino Majorana mass at the SUSY GUT scale and the solution of the solar-neutrino problem
Creators: name: Lavoura, L.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the SUSY GUT scenario, it is natural to assume the right-handed-neutrino Majorana-mass scale to be $10^{16}$ GeV. This will in principle lead, by the seesaw mechanism, to a $ ν_τ $ mass of order $ m_t^2 / (10^{16}\, {\rm GeV}) \sim 3 \times 10^{-3}\, {\rm eV} $. This suggests that the solution of the solar-neutrino puzzle should be either the MSW effect in $ν_e$--$ν_τ$ oscillations, with $ m_{ν_τ}^2 \sim 10^{-5}\, {\rm eV}^2 $, or long-wavelength $ν_e$--$ν_μ$ oscillations, with $ m_{ν_μ}^2 \sim 10^{-10}\, {\rm eV}^2 $. These solutions require unexpectedly large mixings of $ ν_e $ with $ ν_τ $ and $ ν_μ $, respectively. I suggest a variation of the Dimopoulos--Hall--Raby model for the fermion mass matrices which can accomodate such large mixings.
description: 10 pages, standard LATEX, no figures, Carnegie-Mellon University Report CMU-HEP93-27 and DOE-ER/40682-52
#InstaCuba: Viewing Cuban Identity through the Tourist Filter
Creators: name: Giannangeli, Natalie
Publisher: name: Carnegie Mellon University
Year: 2015
Subjects: subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature

description: Throughout history, Western tourists have fetishized the people and cultures of their nonWestern destinations. Tourists have traveled to Latin America imagining scenes of tropical beaches and “exotic-looking” women. Although tourism in Cuba has its specific history and complexities, it is a part of this broader narrative of tourism across Latin America. Prior to 1959, Cuba attracted more tourists than any other Caribbean island, as the Cuban government and travel agencies presented the island as a paradise for tourists’ self-indulgent pleasures. However, the Cuban Revolution in 1959 put an end to the gambling and prostitution that attracted many tourists. After several marginally successful attempts to harbor a tourism industry within the constraints of the socialist ideals, it was not until the fall of the Soviet bloc in the 1990s that the government returned to tourism as a main economic pillar to generate capital and attract hard currency quickly. Realizing tourists’ desires to see a romanticized ideal of the “last socialist country”, the Cuban government promotes celebratory images of the Revolution alongside the capitalist excesses of sex from the 1950s and tropical paradise that once characterized the tourist attractions on the island. American cars and street murals of Che Guevara are common appearances in the images that tourists post on the social media platform, Instagram. While tourists post pictures of destinations throughout Latin America on social media, the case of tourist social media in Cuba is vastly different from other destinations. A lack of infrastructure and government restrictions makes consistent access to the Internet difficult for Cubans. On the island, tourist hotels have Internet service available for purchase, but the service is too costly for the majority of Cuban nationals. Most Cubans remain without the ability to use and contribute to new interactive web spaces, such as Instagram. Therefore, foreigners and the State control the Cuban presence on this social media platform. The images that tourists choose to share perpetuate the idea of Cuba as the last socialist paradise: a representation the Cuban state desires in order to continue to attract tourists and to preserve the image of the survival of socialist ideals, despite an increasingly capitalistic reality. There is an abundance of research regarding tourism and its images, as well as investigation of social networks like Twitter and Facebook’s impact on the tourist industry, but the role of Instagram in the industry has not had the same attention. This paper will explore the intricacies of the identity of Cuba and its people on Instagram.
A discovery of potent kaempferol derivatives as multi-target medicines against diabetes as well as bacterial infections: an in silico approach
Creators: name: Parveen, Shagufta
name: Shehzadi, Saman
name: Shafiq, Nusrat
name: Rashid, Maryam
name: Naz, Sadaf
name: Mehmood, Tahir
name: Riaz, Rabia
name: Almaary, Khalid S.
name: Nafidi, Hiba-Allah
name: Bourhia, Mohammed
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Flavonoids demonstrate beneficial effects on human health because flavonoids contain important biological properties. Kaempferol is a flavonol, type of flavonoid found in eatable plants and in plants usually employed in ancient drugs (Moringa oleifera, Tilia spp., fern genus spp. and gingko etc.). Some medicinal studies have shown that the use of foods full of kaempferol decreases the risk of many (cancer, vascular) diseases. All the data of 50 kaempferol derivatives were collected from PubChem database. Through Schrödinger software, 3D-QSAR study was performed for 50 compounds by using method of field base. Conformer of kaempferol derivatives was docked against anti-diabetic, anti-microbial co-crystal structures and protein. To monitor the best anti-diabetic and antibacterial agent, particular kaempferol derivatives were downloaded from PubChem database. Virtual screening by molecular docking provided four lead compounds with four different proteins. These hit compounds were found to be potent inhibitor for diabetic enzymes alpha-amylase and DPP IV and had the potential to suppress DNA gyrase and dihydrofolate reductase synthesis. Molecular dynamic simulation of docked complexes evaluates the value of root mean square fluctuation by iMOD server. Kaempferol 3-O-alpha-L-(2, 3-di-Z-p-coumaroyl) rhamnoside (42) compound used as anti-diabetic and kaempferol 3-O-gentiobioside (3) as antibacterial with good results can be used for drug discovery.
title: Tööõnnetuste levimus Eesti põllumajanduses aastatel 2008–2017
Creators: name: Enn, Anni
name: Merisalu, Eda
Publisher: name: Agraarteadus
Year: 2019
Subjects: work accidents
agriculture
gender
severity
location
regional distribution
article

description: Occupational accidents in agriculture are a problem all over the world. The costs of accidents are high to the employer and to the national economy as a whole. Work-related ill-health and injury is costing the European Union 3.3% of its GDP. In Estonia, the estimates of the costs of work accidents (WA) in 2012 showed €2.4 billion per year and due to permanent lost workability €25 billion costs in total for society. Even if the most sectors become more automated, there are also self-employed farmers, who cannot always use the newest technologies. At the same time, family members and farm workers are facing risks higher than in most other occupations. Many accidents involve the handling of machinery or animals. The objective of the study was to analyse fatal and non-fatal work accidents by demographic parameters, severity, type, causes and body location of injuries in Estonian agriculture in 2008–2017. Method. The database of accidents in agriculture was obtained from the Estonian Labour Inspectorate and the data by absolute numbers, percentages and incident rates have described. Results. The total number of accidents at work in agriculture was 1696, which formed 4% from the total economic sector. The average incident rate in the past decade was 678 accidents per 100 000 workers. Predominantly minor accidents and usually among male workers have taken place. There are mainly 3 types of injuries – wounds and superficial injuries (40.4% of the total), bone fractures (25.6%) and concussion and internal injuries (16.2%). The most common causes of work accidents are lack of internal control (20.3%), poor instruction (18.5%) and other factors (18.1%). The most often locations of the injuries throughout the years were upper or lower limbs (35.7% and 33.0% respectively). The biggest number of accidents was taken place at Järva county.