cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Socially Distanced Emergencies: Clinicians’ Experience with Tele-behavioral Health Safety Planning
Creators: name: Sowa, Nathaniel A
name: Vitiello, Evan
Publisher: name: Springer Nature
Year: 2022

description:
Psychiatry has experienced a rapid expansion in providing behavioral health services using virtual means; however, little is known regarding clinicians’ experience in managing patient emergencies during virtual encounters. We present survey data from a large academic psychiatry department designed to better understand safety planning while delivering ambulatory tele-behavioral health services during the COVID-19 pandemic. Clinical faculty in the department were sent an anonymous electronic survey developed and distributed using the Qualtrics™ software. Departmental leadership provided a list of clinicians who performed ambulatory care. SAS 9.4 was used to conduct statistical analysis for associations between variables. Approximately one quarter (23.3%) of respondents engaged in proactive safety planning for most of their outpatient virtual visits, while a little over half (53.2%) of clinicians implemented emergent safety planning between just one to five visits. Clinicians who more frequently implemented emergency protocols were more likely to engage in proactive safety planning prior to emergencies (p = 0.0115). 10.8% of participants petitioned for civil commitment, though those that did identified numerous challenges. Our results reinforce the importance in appropriate training regarding best practices while providing tele-behavioral health care, with increased awareness for conducting safety planning and implementing emergent protocols. Furthermore, while petitioning for civil commitment is a relatively low base rate event in a large outpatient practice, these data and narrative feedback help to outline challenges and potential measures to improve this process for all parties. Increased attention to protocols and procedures are key as the utilization of virtual care within psychiatry continues.
Characteristics of Patients With Initial Clostridioides difficile Infection (CDI) That Are Associated With Increased Risk of Multiple CDI Recurrences
Creators: name: Guh, Alice Y.
name: Li, Rongxia
name: Korhonen, Lauren
name: Winston, Lisa G.
name: Parker, Erin
name: Czaja, Christopher A.
name: Johnston, Helen
name: Basiliere, Elizabeth
name: Meek, James
name: Olson, Danyel
name: Fridkin, Scott K.
name: Wilson, Lucy
name: Perlmutter, Rebecca
name: Holzbauer, Stacy M.
name: D’Heilly, Paige
name: Phipps, Erin C.
name: Flores, Kristina G.
name: Dumyati, Ghinwa K.
name: Pierce, Rebecca
name: Ocampo, Valerie L. S.
name: Wilson, Christopher D.
name: Watkins, Jasmine J.
name: Gerding, Dale N.
name: McDonald, L. Clifford
Publisher: name: Oxford University Press
Year: 2024

description: BackgroundBecause interventions are available to prevent further recurrence in patients with recurrent Clostridioides difficile infection (rCDI), we identified predictors of multiple rCDI (mrCDI) in adults at the time of presentation with initial CDI (iCDI).MethodsiCDI was defined as a positive C difficile test in any clinical setting during January 2018–August 2019 in a person aged ?18 years with no known prior positive test. rCDI was defined as a positive test ?14 days from the previous positive test within 180 days after iCDI; mrCDI was defined as ?2 rCDI. We performed multivariable logistic regression analysis.ResultsOf 18 829 patients with iCDI, 882 (4.7%) had mrCDI; 437 with mrCDI and 7484 without mrCDI had full chart reviews. A higher proportion of patients with mrCDI than without mrCDI were aged ?65 years (57.2% vs 40.7%; P < .0001) and had healthcare (59.1% vs 46.9%; P < .0001) and antibiotic (77.3% vs 67.3%; P < .0001) exposures in the 12 weeks preceding iCDI. In multivariable analysis, age ?65 years (adjusted odds ratio [aOR], 1.91; 95% confidence interval [CI], 1.55–2.35), chronic hemodialysis (aOR, 2.28; 95% CI, 1.48–3.51), hospitalization (aOR, 1.64; 95% CI, 1.33–2.01), and nitrofurantoin use (aOR, 1.95; 95% CI, 1.18–3.23) in the 12 weeks preceding iCDI were associated with mrCDI.ConclusionsPatients with iCDI who are older, on hemodialysis, or had recent hospitalization or nitrofurantoin use had increased risk of mrCDI and may benefit from early use of adjunctive therapy to prevent mrCDI. If confirmed, these findings could aid in clinical decision making and interventional study designs.
Collectrin (Tmem27) deficiency in proximal tubules causes hypertension in mice and a TMEM27 variant associates with blood pressure in males in a Latino cohort
Creators: name: Isakson, Brant E
name: Chu, Pei-Lun
name: Cai, Jianwen
name: Wang, Yves T
name: Bodonyi-Kovacs, Gabor
name: Le, Thu H
name: Cechova, Sylvia
name: Gigliotti, Joseph C
name: Wassertheil-Smoller, Sylvia
name: Chen, Luojing
name: Franceschini, Nora
Publisher: name: American Physiological Society
Year: 2022

description:
Collectrin (Tmem27), an angiotensin-converting enzyme 2 homologue, is a chaperone of amino acid transporters in the kidney and endothelium. Global collectrin knockout (KO) mice have hypertension, endothelial dysfunction, exaggerated salt sensitivity, and diminished renal blood flow. This phenotype is associated with altered nitric oxide and superoxide balance and increased proximal tubule (PT) Na+/H+ exchanger isoform 3 (NHE3) expression. Collectrin is located on the X chromosome where genome-wide association population studies have largely been excluded. In the present study, we generated PT-specific collectrin KO (PT KO) mice to determine the precise contribution of PT collectrin in blood pressure homeostasis. We also examined the association of human TMEM27 single-nucleotide polymorphisms with blood pressure traits in 11,926 Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Hispanic/Latino participants. PT KO mice exhibited hypertension, and this was associated with increased baseline NHE3 expression and diminished lithium excretion. However, PT KO mice did not display exaggerated salt sensitivity or a reduction in renal blood flow compared with control mice. Furthermore, PT KO mice exhibited enhanced endothelium-mediated dilation, suggesting a compensatory response to systemic hypertension induced by deficiency of collectrin in the PT. In HCHS/SOL participants, we observed sex-specific single-nucleotide polymorphism associations with diastolic blood pressure. In conclusion, loss of collectrin in the PT is sufficient to induce hypertension, at least in part, through activation of NHE3. Importantly, our model supports the notion that altered renal blood flow may be a determining factor for salt sensitivity. Further studies are needed to investigate the role of the TMEM27 locus on blood pressure and salt sensitivity in humans. NEW & NOTEWORTHY The findings of our study are significant in several ways: 1) loss of an amino acid chaperone in the proximal tubule is sufficient to cause hypertension, 2) the results in global and proximal tubule-specific collectrin knockout mice support the notion that vascular dysfunction is required for salt sensitivity or that impaired renal tubule function causes hypertension but is not sufficient to cause salt sensitivity, and 3) our study is the first to implicate a role of collectrin in human hypertension.
Racial Resentment and the Death Penalty
Creators: name: Baumgartner, Frank R.
name: Duxbury, Scott
name: Caron, Christian
Publisher: name: Cambridge University Press (CUP)
Year: 2022

description:
We explore the annual number of death sentences imposed on black and white offenders within each US state from 1989 through 2017, with particular attention to the impact of aggregate levels of racial resentment. Controlling for general ideological conservatism, homicides, population size, violent crime, institutional and partisan factors, and the inertial nature of death sentencing behavior, we find that racial hostility translates directly into more death sentences, particularly for black offenders. Racial resentment itself reflects each state’s history of racial strife; we show powerful indirect effects of a history of lynching and of racial population shares. These effects are mediated through contemporaneous levels of racial resentment. Our findings raise serious questions about the appropriateness of the ultimate punishment, as they show its deep historical and contemporary connection to white racial hostility toward blacks.
The impact of nanomaterials in enhancing wastewater treatment processes: A review
Creators: name: Ugwuanyi, Ejike David
name: Nwokediegwu, Zamathula Queen Sikhakhane
name: Dada, Michael Ayorinde
name: Majemite, Michael Tega
name: Obaigbena, Alexander
Publisher: name: Magna Scientia Advanced Research and Reviews
Year: 2024

description: The utilization of nanomaterials in wastewater treatment processes has garnered considerable attention due to their unique physicochemical properties and multifaceted applications. This expanded review delves deeper into the transformative impact of nanomaterials on wastewater treatment processes, offering a comprehensive analysis of recent advancements and emerging trends in the field. Nanomaterials, including nanoparticles, nanocomposites, and nanocatalysts, have demonstrated remarkable efficacy in enhancing pollutant removal efficiency, facilitating resource recovery, and promoting environmental sustainability in wastewater treatment systems. Through a detailed examination of key studies and case examples, this review elucidates the diverse mechanisms by which nanomaterials augment treatment performance, including adsorption, catalysis, and membrane filtration. Moreover, it explores the synergistic effects of integrating nanomaterials with conventional treatment technologies, such as activated sludge processes, membrane bioreactors, and advanced oxidation processes, to achieve superior treatment outcomes. In addition to their efficacy in pollutant removal, nanomaterials offer promising prospects for mitigating emerging contaminants, such as pharmaceuticals, personal care products, and microplastics, which pose significant challenges to traditional treatment methods. However, the widespread adoption of nanomaterial-based technologies in wastewater treatment is not without its challenges and considerations. This review addresses critical issues surrounding the environmental fate and impact of nanomaterials, including their potential ecotoxicological effects, persistence in the environment, and regulatory implications. Furthermore, the review underscores the importance of addressing knowledge gaps and advancing research efforts to optimize the design, synthesis, and application of nanomaterials for sustainable wastewater treatment. Future research directions include the development of eco-friendly synthesis methods, assessment of long-term environmental implications, and integration of nanomaterials into holistic water management strategies. By harnessing the transformative potential of nanomaterials and leveraging interdisciplinary collaborations, the wastewater treatment sector can capitalize on innovative solutions to address the pressing challenges of water pollution and scarcity, fostering a cleaner, healthier, and more sustainable environment for future generations.
Additional file 1 of Extracts of Carica papaya L. and Capsicum annuum L. showed comparable efficacy to piperazine citrate and levamisole hydrochloride in treatment of poultry helminths
Creators: name: Zirintunda, Gerald
name: Kateregga, John
name: Nalule, Sarah
name: Biryomumaisho, Savino
name: Omujal, Francis
name: Okwee-Acai, James
name: Vudriko, Patrick
Publisher: name: figshare
Year: 2025
Subjects: Biochemistry
Medicine
Molecular Biology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Virology
Computational Biology

description: Additional file 1.
Artificial intelligence: a strategy to harness its power through organizational learning
Creators: name: Brown, Ashley
name: Donahue, Chelsea
name: Kenyon, Sarah
name: Jarrahi, Mohammad Hossein
name: Wicher, Chris
Publisher: name: Emerald
Year: 2022

description:
Purpose The purpose of this paper is to present a framework that captures the strategic value of artificial intelligence (AI) systems. Although AI has become a crucial component of digital transformation efforts tied to organizational strategy, many firms struggle to derive strategic value from emerging AI systems. Design/methodology/approach The analytical framework in this paper is based on a learning-centered approach. Specifically, by building on the knowledge-based perspective, this paper elaborates on how AI can contribute to organizational learning to create a competitive advantage in knowledge-intensive contexts. Findings This paper argues that the power of AI as a strategic resource lies in its self-learning capacities. Such learning capacities are only realized in partnership with humans through mutual learning. This paper formulates the concept of artificial capital and the ways artificial and human capital can together drive routinization and strategic learning processes that connect internal and external environments of the organization. Originality/value This is a timely contribution as many organizations are considering adopting AI technologies for strategic purposes. This paper translates the proposed framework into several practical implications for managing and developing AI to meet strategic business goals.
Corrigendum to: EGFR, the Lazarus target for precision oncology in glioblastoma
Creators: name: Smithberger, Erin
name: Miller, C Ryan
name: Furnari, Frank B
name: Ziebro, Julia
name: Cloughesy, Timothy F
name: Skinner, Kasey R
name: Binder, Zev A
name: Nathanson, David A
name: O’Rourke, Donald M
name: Lin, Benjamin
name: Zhao, Eva
Publisher: name: Oxford University Press (OUP)
Year: 2022

description:
Corrigendum to "EGFR, the Lazarus target for precision oncology in glioblastoma"
Additional file 1 of Effectiveness of UK-based support interventions and services aimed at adults who have experienced or used domestic and sexual violence and abuse: a systematic review and meta-analysis
Creators: name: Carlisle, Sophie
name: Bunce, Annie
name: Prina, Matthew
name: McManus, Sally
name: Barbosa, Estela
name: Feder, Gene
name: Lewis, Natalia V.
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1. Checklists (PRISMA and SWiM). Contains the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Synthesis Without Meta-analysis (SWiM) reporting checklists.
Additional file 2 of Effectiveness of UK-based support interventions and services aimed at adults who have experienced or used domestic and sexual violence and abuse: a systematic review and meta-analysis
Creators: name: Carlisle, Sophie
name: Bunce, Annie
name: Prina, Matthew
name: McManus, Sally
name: Barbosa, Estela
name: Feder, Gene
name: Lewis, Natalia V.
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 2. Example search strategy. Contains an example search strategy for one of the peer reviewed literature databases (Medline) and one of the grey literature databases (Social Care Online).
EGFR, the Lazarus target for precision oncology in glioblastoma
Creators: name: Binder, Zev A
name: Furnari, Frank B
name: Smithberger, Erin
name: O’Rourke, Donald M
name: Miller, C Ryan
name: Nathanson, David A
name: Lin, Benjamin
name: Skinner, Kasey R
name: Cloughesy, Timothy F
name: Zhao, Eva
name: Ziebro, Julia
Publisher: name: Oxford University Press (OUP)
Year: 2022

description:
The Lazarus effect is a rare condition that happens when someone seemingly dead shows signs of life. The epidermal growth factor receptor (EGFR) represents a target in the fatal neoplasm glioblastoma (GBM) that through a series of negative clinical trials has prompted a vocal subset of the neuro-oncology community to declare this target dead. However, an argument can be made that the core tenets of precision oncology were overlooked in the initial clinical enthusiasm over EGFR as a therapeutic target in GBM. Namely, the wrong drugs were tested on the wrong patients at the wrong time. Furthermore, new insights into the biology of EGFR in GBM vis-à-vis other EGFR-driven neoplasms, such as non-small cell lung cancer, and development of novel GBM-specific EGFR therapeutics resurrects this target for future studies. Here, we will examine the distinct EGFR biology in GBM, how it exacerbates the challenge of treating a CNS neoplasm, how these unique challenges have influenced past and present EGFR-targeted therapeutic design and clinical trials, and what adjustments are needed to therapeutically exploit EGFR in this devastating disease.
Supplementary document for Extract more randomness using dimension witness - 5765648.pdf
Creators: name: Zhou, Yao
name: Zhong, Zhen-Qiu
name: Yin, Zhen-Qiang
name: Wang, Rong
name: Zhan, Xiao-Hai
name: Wang, Shuang
name: Chen, Wei
name: Huang, Wei
name: Xu, Bingjie
name: Guo, Guang-can
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Some derivation details
Additional file 3 of Effectiveness of UK-based support interventions and services aimed at adults who have experienced or used domestic and sexual violence and abuse: a systematic review and meta-analysis
Creators: name: Carlisle, Sophie
name: Bunce, Annie
name: Prina, Matthew
name: McManus, Sally
name: Barbosa, Estela
name: Feder, Gene
name: Lewis, Natalia V.
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 3. Risk of bias assessments. Contains tables A1 and A2, detailing the risk of bias assessments for randomised controlled trials, non-randomised comparative trials and uncontrolled before and after studies (Table A1), and for the grey literature (Table A2).
Vaccinating children against COVID-19 is crucial to protect schools and communities
Creators: name: Smith, Raymond L
name: Lich, Kristen Hassmiller
name: Swann, Julie L
name: Delamater, Paul L
name: Patel, Mehul D
name: Rosenstrom, Erik T
name: Ivy, Julie S
name: Mele, Jessica
name: Mayorga, Maria E
Publisher: name: Oxford University Press (OUP)
Year: 2022

description:
To evaluate the joint impact of childhood vaccination rates and school masking policies on community transmission and severe outcomes due to COVID-19, we utilized a stochastic, agent-based simulation of North Carolina to test 24 health policy scenarios. In these scenarios, we varied the childhood (ages 5 to 19) vaccination rate relative to the adult's (ages 20 to 64) vaccination rate and the masking relaxation policies in schools. We measured the overall incidence of disease, COVID-19-related hospitalization, and mortality from 2021 July 1 to 2023 July 1. Our simulation estimates that removing all masks in schools in January 2022 could lead to a 31% to 45%, 23% to 35%, and 13% to 19% increase in cumulative infections for ages 5 to 9, 10 to 19, and the total population, respectively, depending on the childhood vaccination rate. Additionally, achieving a childhood vaccine uptake rate of 50% of adults could lead to a 31% to 39% reduction in peak hospitalizations overall masking scenarios compared with not vaccinating this group. Finally, our simulation estimates that increasing vaccination uptake for the entire eligible population can reduce peak hospitalizations in 2022 by an average of 83% and 87% across all masking scenarios compared to the scenarios where no children are vaccinated. Our simulation suggests that high vaccination uptake among both children and adults is necessary to mitigate the increase in infections from mask removal in schools and workplaces.
Implementation of a cardiac arrest prevention bundle in the pediatric intensive care unit: a quality improvement project
Creators: name: Davault, Hillary
Publisher: name: Oregon Health and Science University
Year: 2024
Subjects: subject: Intensive Care Units, Pediatric
subject: Nurses, Pediatric
subject: Heart Arrest
subject: cardiac arrest
subject: pediatrics
subject: nursing empowerment
subject: pediatric intensive care unit

description: Cardiac arrest (CA) in pediatric cardiac patients remains a major concern, with in-hospital rates posing significant challenges. Despite quality improvement initiatives, survival improvements have plateaued, prompting the implementation of a Cardiac Arrest Prevention (CAP) bundle at OHSU’s Pediatric Intensive Care Unit to enhance early intervention and situational awareness with the ultimate goal of decreasing CA events amongst pediatric cardiac patients.
Schultz fuchsii Kotula
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S,nemorensis L. s.ampl. Ssp. Jacquinianus (Rchb.) Durand (S. JacquinianusRchb.) Cat. 202. Angegeben von 0. Meylan aus Distr. 3: Oberems (ob sicher?). Ssp. Fuchsii (Gmelin) Kotula (S. Fuchsii Gmelin) Cat. 202 und 428. Obere Höhengrenze festzustellen. Die Angabe des Cat.: 1930 m, ist wohl zu hoch; JACCARD sstzte diese Zahl willkürlich (offenbar mit Bezug auf die MumTHsche Fundstelle «Les Planards» [=welche?]). l: Alpen vonVerossaz (J.); Evionnaz-Cocorier (F.); Charavex (Besse); Alpen von Outre-Rhöne (J., Besse). - 3:Rhoneufer bei Martigny (F.); Fionnay (Miller); Chemin (F.); Combe de Rechy (Garns); Turtmanntal (Garns, Maillefer); Laubbach ob Turtig (Zwicky); «Saastal» (Miller), gegenauer: zwischen Huteggen und Baien (Huber, Hirschmann). - 3a: Gabi und Umgebung (Becherer); unteres Zwischbergental, mehrfach (idem). Var.vallesiacus (Beck) - l: La Forclaz (Schinz). Var.graniticus (Beck) - l: Gorge du Trient (Garns);Hautd'Arbignon(idem).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Quantifying Recent Storm-Induced Change on a Small Fetch-Limited Barrier Island along North Carolina’s Crystal Coast Using Aerial Imagery and LiDAR
Creators: name: Rubino, Brian
name: Colli, Christopher
name: Valdes-Weaver, Lexia M.
name: Henry, Brian
name: Peñalver, Manuel Merello
name: Henne, Carter
name: Lindquist, Niels L.
name: Sirianni, Hannah
name: Moody, Michael
name: Sirianni, Matthew J.
name: Mallinson, David J.
Publisher: name: MDPI
Year: 2022

description:
Barrier islands within sheltered environments are an important natural defense from severe storm impacts for coastal communities worldwide. Despite their importance, these fetch-limited barrier islands remain understudied and their ability to withstand and recover from storms is not well-understood. Here, we present a case study of Sugarloaf Island in North Carolina that demonstrates the operational use of openly accessible LiDAR and aerial imagery data to quantify synoptic habitat, shoreline, and volumetric change between 2014 and 2020, a period that encompasses four hurricanes and a winter storm event. During this time period, our results show: (1) an 11–13% decrease in marsh and shrub habitat, (2) an average landward shoreline migration of 2.9 m yr−1 and up to 5.2 m yr−1 in extreme areas, and (3) a net volume loss of approximately 9800 m3. The results of this study highlight the importance of storms as a driver of morphologic change on Sugarloaf Island and have implications for better understanding the resiliency of fetch-limited barrier islands to storms. This work helps to enhance prerestoration data availability and supports knowledge-based decision-making regarding habitat change, erosional issues, and the efficacy of nature-based solutions to increase the resiliency of a coastal community in North Carolina.
ROI054, The New Castle Site Revisited
Creators: name: McCord, Beth K.
Publisher: name: Archaeological Resources Management Service, Ball State University
Year: 1999
Subjects: subject: Henry County
valueUri: https://core.tdar.org/browse/geographic-keyword/85408/henry-county
subject: Indiana
valueUri: https://core.tdar.org/browse/geographic-keyword/44778/indiana
subject: Early Woodland
valueUri: https://core.tdar.org/browse/culture-keyword/14/early-woodland
subject: Adena
valueUri: https://core.tdar.org/browse/culture-keyword/798/adena
subject: Middle Woodland
valueUri: https://core.tdar.org/browse/culture-keyword/15/middle-woodland
subject: Hopewell
valueUri: https://core.tdar.org/browse/culture-keyword/12/hopewell
subject: 12Hn1
valueUri: https://core.tdar.org/browse/site-name/119414/12hn1
subject: Mound / Earthwork
valueUri: https://core.tdar.org/browse/site-type/323/mound-earthwork
subject: Site Evaluation / Testing
valueUri: https://core.tdar.org/browse/investigation-type/10/site-evaluation-testing
subject: Systematic Survey
valueUri: https://core.tdar.org/browse/investigation-type/12/systematic-survey

description: The Archaeological Resources Management Service (ARMS) at Ball State University conducted a FY98 Historic Preservation Fund Grant to further assess the condition of the New Castle site (12Hn1). The project conducted a shovel probe survey of the site area documenting prehistoric use and historic disturbance of the area. No prehistoric activity areas associated with the earthworks were recorded. Historic disturbance to the site area was extensive. Limited test excavations at each of the extant earthworks were also performed. The excavations documented a consistent pattern of construction. In addition, portions of 4 previously excavated units (Swartz 1976) were reopened. These units documented a more complex construction of Mound 1 and Mound 4 than reported. They also provided the impetus for critically reviewing previous interpretations of the site.
The project documented that the site structures were far more complex than previously documented. While the project obtained new information, it was found that the site was still inadequately understood. Interpretations of the site were limited by the lack of data, ie., no radiocarbon dates associated with the earthworks were obtained. Further excavation of the site and a comprehensive review of previous excavations were recommended.
Hybridization and introgression in deeply differentiated salamander species – molecular genetics and a reappraisal of Dr. Louis Vallée’s osteological data
Creators: name: W. Arntzen, Jan
Publisher: name: Brill Online
Year: 2024
Subjects: classificationCode: 310499
subject: Evolutionary biology not elsewhere classified

description: Two morphologically and genetically distinct salamander species (the crested newt, Triturus cristatus and the marbled newt, T. marmoratus) engage over a large area in the west of France where they hybridize at ca. 4%. The species interaction is characterized by ecological differentiation and limited gene flow beyond the F1 hybrid generation. Incompletely isolated species like these allow to investigate the genetic mechanisms and evolutionary forces that maintain their identity in the face of ongoing gene flow, to which a large mosaic hybrid zone provides excellent opportunities. A reanalysis of published morphological data supports the partial breakdown of the species barrier whereas extensive genetic data show that introgression is low yet asymmetric, in line with the dynamics of species replacement inferred earlier. The current work, with seven diagnostic nuclear markers studied for a large sample, revises the estimates of introgression in both T. cristatus (to 0.24 %) and T. marmoratus (to 0.11 %). Difficulties remain in the recognition of potential triploid hybrids versus backcross hybrids. Haldane’s rule is partially supported, but deeper analyses require the use of a molecular marker for sex that is not yet available.
Intracellular allosteric antagonist of the olfactory receptor OR51E2
Creators: name: Kenakin, Terry
name: Abaffy, Tatjana
name: Goldenberg, Josh M
name: Harume-Nagai, Maira
name: Fu, Olivia
name: Kenyon, Victor
Publisher: name: American Society for Pharmacology & Experimental Therapeutics (ASPET)
Year: 2024

description:
Olfactory receptors are members of class A (rhodopsin-like) family of G protein-coupled receptors (GPCRs). Their expression and function have been increasingly studied in nonolfactory tissues, and many have been identified as potential therapeutic targets. In this manuscript, we focus on the discovery of novel ligands for the olfactory receptor family 51 subfamily E2 (OR51E2). We performed an artificial intelligence-based virtual drug screen of a ∼2.2 million small molecule library. Cell-based functional assay identified compound 80 (C80) as an antagonist and inverse agonist, and detailed pharmacological analysis revealed C80 acts as a negative allosteric modulator by significantly decreasing the agonist efficacy, while having a minimal effect on receptor affinity for agonist. C80 binds to an allosteric binding site formed by a network of nine residues localized in the intracellular parts of transmembrane domains 3, 5, 6, 7, and H8, which also partially overlaps with a G protein binding site. Mutational experiments of residues involved in C80 binding uncovered the significance of the C2406.37 position in blocking the activation-related conformational change and keeping the receptor in the inactive form. Our study provides a mechanistic understanding of the negative allosteric action of C80 on agonist-ctivated OR51E2. We believe the identification of the antagonist of OR51E2 will enable a multitude of studies aiming to determine the functional role of this receptor in specific biologic processes. SIGNIFICANCE STATEMENT: OR51E2 has been implicated in various biological processes, and its antagonists that can effectively modulate its activity have therapeutic potential. Here we report the discovery of a negative allosteric modulator of OR51E2 and provide a mechanistic understanding of its action. We demonstrate that this modulator has an inhibitory effect on the efficacy of the agonist for the receptor and reveal a network of nine residues that constitute its binding pocket, which also partially overlaps with the G protein binding site.
Additional file 4 of Effectiveness of UK-based support interventions and services aimed at adults who have experienced or used domestic and sexual violence and abuse: a systematic review and meta-analysis
Creators: name: Carlisle, Sophie
name: Bunce, Annie
name: Prina, Matthew
name: McManus, Sally
name: Barbosa, Estela
name: Feder, Gene
name: Lewis, Natalia V.
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 4. GRADE Certainty Assessment. Contains Table A3, which details the assessments of certainty for each of the outcomes using the GRADE framework.
The Impacts of Hidradenitis Suppurativa on Education and Employment: A Scoping Review Protocol
Creators: name: Jones, Emily
name: Mallela, Teja
name: Cheever, C. Ray
name: Sayed, Christopher
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2025

description:
Objective: The objective of this scoping review is to understand the extent and type of evidence regarding the impacts of hidradenitis suppurativa (HS) on education and employment status.


Introduction: HS, an inflammatory skin condition affecting the apocrine glands and hair follicles, entails substantial burdens to patients, including severe pain and resulting physical impairments pose a significant mortality risk. A better understanding of the impacts of HS on educational attainment and employment status may shape care guidelines for patients with HS.


Inclusion criteria: Studies that will be included in the scoping review are those that investigate patients with HS specifying education- or employment-related variables and outcomes. Studies concerning patients with HS but lacking education or employment related data, and studies concerning all other dermatological conditions will be excluded.


Methods: A comprehensive search will be conducted on PubMed, Scopus, CINAHL, ProQuest Health & Medical Collection, and Academic Search Premier. No date limits will be applied, only articles in English languagewill be included, and search terms will include HS and education- and employment-related terms. A minimum of two, independent reviewers will use Covidence to screen articles. Results will be presented using tabulated and thematic displays.


Results: Results will ideally inform care for HS to ensure educational attainment and employment.


Conclusions: Gaps and limitations in the relationship between HS, education, and employment, and future research directions will be presented.
Additional file 5 of Effectiveness of UK-based support interventions and services aimed at adults who have experienced or used domestic and sexual violence and abuse: a systematic review and meta-analysis
Creators: name: Carlisle, Sophie
name: Bunce, Annie
name: Prina, Matthew
name: McManus, Sally
name: Barbosa, Estela
name: Feder, Gene
name: Lewis, Natalia V.
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 5. Sensitivity analyses (leave one out analysis). Contains Figures A1 and A2 which show the leave one out analyses for the Cessation of Abuse outcome for advocacy/IDVA interventions outcome, and the Cessation of Abuse outcome for outreach interventions outcome.
Brushless DC Motor Controlled with Microcontroller for Electric Tricycle
Creators: name: Chalermpol Rueangpattanawiwat
name: Yuttana Kanthapayao
Publisher: name: Rajamangala University of Technology Lanna
Year: 2016
Subjects: brushless DC motor, electrical tricycle, hall sensor

description: 1, 1, RMUTL Engineering Journal
ESSTECH-CM-2023-2 cruise,Côtes De La Manche R/V
Creators: name: MARTIN Victor
Publisher: name: Sismer
Year: 2023

description: Campagne d'essais techniques pour la mise en service d'un nouveau navire-équipement de pêche dédié à bord (panneaux de chalut, treuils, tambour à filet, etc.).
Schultz incanus L.
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S. incanus L. Cat. 202 und 428. In der ssp. eu-incanus (Hermann) J.Braun (S. inc. var. typicus Fiori, S. inc. var. eu-incanus Hermann). Obere Höhengrenze festzustellen. Die von mehreren neueren Werken (HEGI, SCHRÖTER u. a.) wiederholte Angabe des Cat.: 3400 m, ist nicht gesichert. JACCARD sagt nicht, auf welchen Fundort sichdieseZahlbezieht:siehängtin der Luftundist wohl von JACCARDkonstruiert. Bei den Fundorten gibt er nur an ein e r Stelle eine Zahl: Hohtäligrat, «3300 m» (Eigenbeobachtung). Diese Zahl ist erstens etwaszu hoch:der höchstePunkt des genannten Grates (östlich vom Gornergrat, bei Zermatt) liegt bei 3286 m, und dann ist es keineswegs sicher, dass JACCARD die Art an der obersten Stelle festgestellt hat. Abwärtsbis 1770m: Emosson,an der Barberine (P.Jaccard),wohl herabgeschwemmt. l: Luisin (J.); Col d'Emaney (P.); Emosson (vgl. vorstehend); Barberine (Exk. Soc. Murith.); Col deTanneverge (Briquet); ChevalBlanc (idem); Arpille (J., Villaret). - 2: Rawil (Beauverd); Galmalp (J.); Faldumalp (J.); Oberaletschgletscher (Marietan). - 3: Penninische Kette ver- breitet. Angegeben wurden: var. elatior Shuttlew. in Mag. cit., S. 194 (1838) (Findelen bei Zermatt [Shuttleworth 1835]); var. glabratus DC. (Monts Telliers am Gr. St. Bernhard [Melly]); f. integrifoliusVaccariet M:elly (Gr. St. Bernhard [idem]); f. laxusVaccari (Gr. St. Bernhard [Vaccari]).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
title: Sabino Pera Yébenes: La idea del alma y el Más Allá en los cultos orientales durante el Imperio romano Madrid-Salamanca. Signifer Libros, 2012 100 pp. ISBN: 978-84-938991-2-7
Creators: name: Prazeres, Raquel
Publisher: name: CHAM - Centro de História de Além-Mar, Faculdade de Ciências Sociais e Humanas, Universidade NOVA de Lisboa.
Year: 2012

description: Prazeres, Raquel (2012). Sabino Perea Yébenes: La idea del alma y el Más Allá en los cultos orientales durante el Imperio romano Madrid-Salamanca. Signifer Libros, 2012 100 pp. ISBN: 978-84-938991-2-7. Res Antiquitatis. Journal of Ancient History, 3, pp. 307-312. ISSN: 1647-5852
Additional file 1 of Chronic intermittent hypoxia disrupts protective microgliosis in ischemic proliferative retinopathy
Creators: name: Yang, Tianxiang
name: Ronning, Kaitryn E.
name: Augustin, Sébastien
name: Blond, Frédéric
name: Nous, Caroline
name: Argyriou, Foteini
name: Touhami, Sara
name: Delarasse, Cécile
name: Guillonneau, Xavier
name: Sennlaub, Florian
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Hematology

description: Supplementary Material 1
ROI063, SR 129 Rehabilitation INDOT Project #STP-3378 (), Des #9502690, Switzerland County, Indiana: Archaeological Testing of Site 12Sw339
Creators: name: Cochran, Blake
name: Erb, Ezra
name: McCord, Beth K.
name: Nagle, Kimberly
name: Zunker, Kimberly
Publisher: name: Archaeological Resources Management Service, Ball State University
Year: 2002
Subjects: subject: Indiana
valueUri: https://core.tdar.org/browse/geographic-keyword/44778/indiana
subject: Switzerland County
valueUri: https://core.tdar.org/browse/geographic-keyword/85417/switzerland-county
subject: Early Woodland
valueUri: https://core.tdar.org/browse/culture-keyword/14/early-woodland
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Unidentified Prehistoric
valueUri: https://core.tdar.org/browse/culture-keyword/9385/unidentified-prehistoric
subject: 12Sw327
valueUri: https://core.tdar.org/browse/site-name/119528/12sw327
subject: 12Sw339
valueUri: https://core.tdar.org/browse/site-name/119529/12sw339
subject: Artifact Scatter
valueUri: https://core.tdar.org/browse/site-type/340/artifact-scatter
subject: Isolated Artifact
valueUri: https://core.tdar.org/browse/site-type/344/isolated-artifact
subject: Data Recovery / Excavation
valueUri: https://core.tdar.org/browse/investigation-type/5/data-recovery-excavation
subject: Systematic Survey
valueUri: https://core.tdar.org/browse/investigation-type/12/systematic-survey

description: Site 12Sw339 is a multicomponent historic and prehistoric site located on a section of Illinoian till plain south of Moorefield, Switzerland county, Indiana. Archaeological testing revealed that the main occupation was mid 19th century to early 20th century, with a minor prehistoric occupation. A total of three historic cultural features were identified at the site. These include a limestone well, a coal concentration/stain, and a brick and limestone house foundation. No prehistoric features were found. The prehistoric assemblage seems to represent a short term occupation. No further work was recommended for the site.

3D models of the artifacts recovered from Report of Investigations 063, Archaeological Testing of Site 12SW327: SR 129 Rehabilitation, INDOT Project #STP-3378(), Des #950290, Switzerland County, Indiana, can be viewed using the following link: https://skfb.ly/oWCws
Additional file 2 of Chronic intermittent hypoxia disrupts protective microgliosis in ischemic proliferative retinopathy
Creators: name: Yang, Tianxiang
name: Ronning, Kaitryn E.
name: Augustin, Sébastien
name: Blond, Frédéric
name: Nous, Caroline
name: Argyriou, Foteini
name: Touhami, Sara
name: Delarasse, Cécile
name: Guillonneau, Xavier
name: Sennlaub, Florian
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Hematology

description: Supplementary Material 2
Schultz viscosus L.
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S. viscosus L. Cat. 201 Bis gegen 2900 m: Südhang des Gornergrates bei Zermatt, als Lägerbalmenpflanze (Garns; nach Morton und Garns Lit. 1925, S. 180). l: Ob Tanay (Briquet); Illarsaz (Marietan); ob Verossaz (Briquet). - 2:Grand Chavalard, 2100 m (Garns); Lötschental(J.). - 3:Valsorey,bis2280 m (Guyot); ob Arolla (J-); Randa-Domhütte, 2200m (Huber);Zermatt:mehrfach (Thellung, Sulgeru.a.), hoheStellesiehevorstehend;Visperterminen (J.); Brig (Wilczek). - 3a: Simplon-Dorf; Gabi; Gondoschlucht; Bidemji im Zwischbergental (alles: Becherer). - 4: Ob Reckingen (Thommen); bei Ulrichen (Binz).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Ptarmica vulgaris L.
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S. vulgaris L. Cat. 201. Bis 2565m: beimHotel Riffelberg ob Zermatt, Dungstelle, fünfExemplare (Becherer 1950). Forma sordidus Peterm. - 3: Riddes (Garns).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Design of an AC/DC Converter with using Supercapacitors as Energy Storage
Creators: name: Pisit Wisutmetheekorn
name: Viboon Chunkag
Publisher: name: Rajamangala University of Technology Lanna
Year: 2016
Subjects: Supercapacitors, AC/DC converter, Bidirectional DC/DC converter

description: 1, 1, RMUTL Engineering Journal
The Potential of Methane Production of the Dwarf Napier under Alkaline Pretreatment
Creators: name: Ninlawan Chaitanoo
name: Warut Chomjaroan
name: Anupan Wannapira
name: Romsai Mukmuangthong
Publisher: name: Rajamangala University of Technology Lanna
Year: 2016
Subjects: Methane Gas, Biogas Production, Biochemical Methane Potential, Dwarf Napier

description: 1, 1, RMUTL Engineering Journal
Schultz jacobaea L.
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S. Jacobaea L. Cat. 202 und 428. Bis 1600 m: Outre-Rhone (Garns). 3: Bagnes-Lourtier (J.); Riddes (J.).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
ROI105, Scale and Community in Hopewell Networks at Fort Ancient and Newark Earthworks: an expansion study
Creators: name: Olson, Eric C.
name: Nolan, Kevin C.
name: Shott, Michael J.
Publisher: name: Applied Anthropology Laboratories, Ball State University
Year: 2018
Subjects: subject: Warren County
valueUri: https://core.tdar.org/browse/geographic-keyword/4612/warren-county
subject: Ohio
valueUri: https://core.tdar.org/browse/geographic-keyword/24629/ohio
subject: Licking County
valueUri: https://core.tdar.org/browse/geographic-keyword/85418/licking-county
subject: Collections Research
valueUri: https://core.tdar.org/browse/investigation-type/3/collections-research

description: Just as Rome was not built in a day, the great Hopewell earthwork complexes were not built in a day, or in a social vacuum. We know a great deal about the earthworks, but much less about the societies that created them. Hopewell people were interacting with one another, but the social networks they were forming and dissolving is poorly understood. Understanding these social networks is vital to ultimately understanding how and why these earthworks were created. “Scale and Community in Hopewell Networks: Expansion” (SCHoNE) builds upon previous research to create multi-scale, empirical understandings of the nature and structure of Middle Woodland period interaction. The expansion study focused on the Fort Ancient and Newark Earthworks. The key findings of SCHoNE are that the occupants and visitors to Ft. Ancient and Newark and of sites around these ceremonial centers were engaging in social networks oriented in various directions with degree of participation varying by location and possibly through time.
Schultz aquaticus Hudson
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S. aquaticus Hudson Cat. 202. Im untersten Wallis (Distr. l). Keine neuen Fundorte bekanntgeworden.
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
title: ETCSL – The Electronic Text Corpus of Sumerian Literature
Creators: name: Rosa, Maria de Fátima
Publisher: name: CHAM - Centro de História de Além-Mar, Faculdade de Ciências Sociais e Humanas, Universidade NOVA de Lisboa
Year: 2012

description: Rosa, Maria de Fátima (2012). ETCSL – The Electronic Text Corpus of Sumerian Literature. Res Antiquitatis. Journal of Ancient History, 3, pp. 313-317. ISSN: 1647-5852
THE ROLE OF VIRGIN COCONUT OIL IN CARDIOVASCULAR HEALTH: EFFECTS ON LIPID PROFILE AND C-REACTIVE PROTEIN IN ACUTE CORONARY SYNDROME
Creators: name: Noor, Aisha Rahman
name: Muhammad, Idris Farooq
name: Amina, Sofia Karim
Publisher: name: Continental Journal
Year: 2024
Subjects: Acute Coronary Syndrome (ACS), Cardiovascular Disease, Statins, Preventive Medication, Side Effects

description: Acute Coronary Syndrome (ACS) presents a burgeoning health concern, marked by an alarming rise in its incidence annually. Statistics underscore its prominence, with the Ministry of Health Malaysia (2017) highlighting cardiovascular diseases as the leading cause of death since the early 1980s. In 2017, non-communicable diseases accounted for a staggering 73% of deaths in Malaysia, with cardiovascular disease standing out as a significant contributor (Ministry of Health Malaysia, 2017a,b). Recognized globally as a critical health issue by the World Health Organization (WHO), ACS demands meticulous strategies for effective management and treatment. In the Malaysian context, statins emerge as a pivotal pharmacological intervention for lowering lipid levels and preventing ACS. Statins, a class of prescription drugs, are specifically designed to mitigate cholesterol levels (Newman et al, 2019). However, their use is not without consequences, as evidenced by statin-related side effects, primarily manifesting as muscle-related issues such as pain, lethargy, weakness, and myopathy (Deichmann et al, 2010; QuMin et al, 2018). This abstract aims to shed light on the pressing issue of ACS, emphasizing its increasing prevalence and the pivotal role of statins in preventive medication within the Malaysian healthcare landscape. By critically examining the statistics and healthcare landscape provided by the Ministry of Health Malaysia, we underscore the urgency of developing effective strategies for ACS management. Furthermore, we delve into the pharmacological aspect, exploring the use of statins as a primary intervention for lipid level control. However, the abstract also acknowledges the associated challenges, particularly the notable side effects of statins reported in observational studies. Muscle-related problems, affecting 10% to 30% of patients in these studies, become a focal point for discussion, necessitating a balanced approach in ACS prevention and treatment