cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A genome-wide association study meta-analysis of clinical fracture in 10,012 African American women
Creators: name: Psaty, B.
name: Lewis, B.
name: Liu, Y.
name: Rotter, J.I.
name: Franceschini, N.
name: North, K.E.
name: Garcia, M.
name: Cauley, J.A.
name: Robbins, J.A.
name: Stefanick, M.L.
name: Sofer, T.
name: Liu, Y.
name: LaCroix, A.Z.
name: Jackson, R.D.
name: Edwards, D.R.V.
name: Jordan, J.M.
name: Giri, A.
name: Edwards, T.L.
name: Harris, T.
name: Taylor, K.C.
name: Donneyong, M.
name: Li, G.
name: Evans, D.S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Background Osteoporosis is a major public health problem associated with excess disability and mortality. It is estimated that 50–70% of the variation in osteoporotic fracture risk is attributable to genetic factors. The purpose of this hypothesis-generating study was to identify possible genetic determinants of fracture among African American (AA) women in a GWAS meta-analysis. Methods Data on clinical fractures (all fractures except fingers, toes, face, skull or sternum) were analyzed among AA female participants in the Women's Health Initiative (WHI) (N = 8155), Cardiovascular Health Study (CHS) (N = 504), BioVU (N = 704), Health ABC (N = 651), and the Johnston County Osteoarthritis Project (JoCoOA) (N = 291). Affymetrix (WHI) and Illumina (Health ABC, JoCoOA, BioVU, CHS) GWAS panels were used for genotyping, and a 1:1 ratio of YRI:CEU HapMap haplotypes was used as an imputation reference panel. We used Cox proportional hazard models or logistic regression to evaluate the association of ~ 2.5 million SNPs with fracture risk, adjusting for ancestry, age, and geographic region where applicable. We conducted a fixed-effects, inverse variance-weighted meta-analysis. Genome-wide significance was set at P < 5 × 10− 8. Results One SNP, rs12775980 in an intron of SVIL on chromosome 10p11.2, reached genome-wide significance (P = 4.0 × 10− 8). Although this SNP has a low minor allele frequency (0.03), there was no evidence for heterogeneity of effects across the studies (I2 = 0). This locus was not reported in any previous osteoporosis-related GWA studies. We also interrogated previously reported GWA-significant loci associated with fracture or bone mineral density in our data. One locus (SMOC1) generalized, but overall there was not substantial evidence of generalization. Possible reasons for the lack of generalization are discussed. Conclusion This GWAS meta-analysis of fractures in African American women identified a potentially novel locus in the supervillin gene, which encodes a platelet-associated factor and was previously associated with platelet thrombus formation in African Americans. If validated in other populations of African descent, these findings suggest potential new mechanisms involved in fracture that may be particularly important among African Americans.
A generalization of Hausdorff dimension applied to Hilbert cubes and Wasserstein spaces
Creators: name: Kloeckner, Benoit
Publisher: name: arXiv
Year: 2011
Subjects: subject: Metric Geometry (math.MG)
subject: Differential Geometry (math.DG)
subject: Dynamical Systems (math.DS)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: A Wasserstein spaces is a metric space of sufficiently concentrated probability measures over a general metric space. The main goal of this paper is to estimate the largeness of Wasserstein spaces, in a sense to be precised. In a first part, we generalize the Hausdorff dimension by defining a family of bi-Lipschitz invariants, called critical parameters, that measure largeness for infinite-dimensional metric spaces. Basic properties of these invariants are given, and they are estimated for a naturel set of spaces generalizing the usual Hilbert cube. In a second part, we estimate the value of these new invariants in the case of some Wasserstein spaces, as well as the dynamical complexity of push-forward maps. The lower bounds rely on several embedding results; for example we provide bi-Lipschitz embeddings of all powers of any space inside its Wasserstein space, with uniform bound and we prove that the Wasserstein space of a d-manifold has "power-exponential" critical parameter equal to d.
description: v2 Largely expanded version, as reflected by the change of title; all part I on generalized Hausdorff dimension is new, as well as the embedding of Hilbert cubes into Wasserstein spaces. v3 modified according to the referee final remarks ; to appear in Journal of Topology and Analysis
Lavoro di gruppo e apprendimento individuale
Creators: name: Mazzantini, Elisa
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2012

description: Questo lavoro di diploma prende le mosse da una situazione reale in cui spesso si trovano gli insegnanti e cioè quando l’analisi dei risultati di una verifica mostra che all’interno della classe non vi è stato un reale apprendimento e non sono stati raggiunti gli obiettivi prefissati. Questo “fallimento” nel campo delle scienze ha sovente a che vedere con il mancato superamento degli ostacoli cognitivi che gli allievi incontrano sul cammino della costruzione delle loro conoscenze. La presente ricerca propone la metodologia dei gruppi di apprendimento di Meirieu come strumento efficace per preparare attività di rimediazione che permettano agli allievi, grazie all’instaurarsi del conflitto socio-cognitivo con i compagni, di superare i propri ostacoli cognitivi e di poter apprendere. I risultati di questa ricerca appaiono promettenti: infatti analizzando un post-test sottoposto agli allievi, a seguito di alcune attività di gruppo, posso affermare che la maggior parte ha potuto sviluppare le proprie conoscenze condizionali e procedurali, dimostrando quindi capacità di ragionamento e di collegamento fra diversi argomenti, e questo è possibile solo se avviene un apprendimento di tipo trasformativo. Tale metodologia si è dimostrata valida anche per affrontare una nuova unità didattica e i risultati del post-test sottoposto agli allievi al termine del percorso evidenzia un’ulteriore crescita della loro capacità di risolvere situazioni-problema. Rimangono tuttavia aperte alcune questioni circa il recupero delle attività da parte di allievi assenti e il miglioramento delle capacità di studio personale. Relatore: Cleto Canonica. Materia: scienze dell'educazione
Three-dimensional surface convection simulations of metal-poor stars -- The effect of scattering on the photospheric temperature stratification
Creators: name: Collet, R.
name: Hayek, W.
name: Asplund, M.
name: Nordlund, Å.
name: Trampedach, R.
name: Gudiksen, B.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Three-dimensional (3D) radiative hydrodynamic model atmospheres of metal-poor late-type stars are characterized by cooler upper photospheric layers than their 1D counterparts. This property of 3D models can dramatically affect elemental abundances derived from temperature-sensitive spectral lines. We investigate whether the cool surface temperatures predicted by metal-poor 3D models can be ascribed to the approximated treatment of scattering in the radiative transfer. We use the Bifrost code to test three different ways to handle scattering in 3D model atmospheres of metal-poor stars. First, we solve self-consistently the radiative transfer equation for a source function with a coherent scattering term. Second, we solve the radiative transfer equation for a Planckian source function, neglecting the contribution of continuum scattering to extinction in the optically thin layers; this has been the default mode in previous models of ours. Third, we treat scattering as pure absorption everywhere, which is the standard case in CO5BOLD models. We find that the second approach produces temperature structures with cool upper photospheric layers very similar to the correct coherent scattering solution. In contrast, treating scattering as pure absorption leads to significantly hotter and shallower temperature stratifications. The main differences in temperature structure between our published models and those generated with the CO5BOLD code can be traced to the different treatments of scattering. Neglecting the contribution of continuum scattering to extinction in optically thin layers provides a good approximation to the full radiative transfer solution for metal-poor stars. Our results demonstrate that the cool temperature stratifications predicted for metal-poor late-type stellar atmospheres by previous models of ours are not an artifact of the approximated treatment of scattering.
description: 12 pages, accepted for publication on A&A
On the parity complexity measures of Boolean functions
Creators: name: Zhang, Zhiqiang
name: Shi, Yaoyun
Publisher: name: arXiv
Year: 2010
Subjects: subject: Computational Complexity (cs.CC)
subject: FOS: Computer and information sciences

description: The parity decision tree model extends the decision tree model by allowing the computation of a parity function in one step. We prove that the deterministic parity decision tree complexity of any Boolean function is polynomially related to the non-deterministic complexity of the function or its complement. We also show that they are polynomially related to an analogue of the block sensitivity. We further study parity decision trees in their relations with an intermediate variant of the decision trees, as well as with communication complexity.
description: submitted to TCS on 16-MAR-2009
An exploration of social photography in a visitor museum experience: Understanding engagement and communication through a mixed methods study incorporating service design
Creators: name: Hou, Ling
Publisher: name: Loughborough University
Year: 2022
Subjects: subject: 199999 Studies in the Creative Arts and Writing not elsewhere classified
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: The widespread use of social media and digital cameras in people’s daily lives has reshaped how visitors experience museums. The continuous development of smartphones with built-in cameras has encouraged more and more people to use photography to engage with exhibition content, to document their museum experiences, and to communicate their thoughts about these experiences. The museum experience has been transformed even more dynamically through the ability to share photos via social media. Visitor photography is increasingly becoming an important part of the museum experience, but limited research has been conducted to investigate this phenomenon. This research, thus, sets out to understand how visitors use Instagram to convey information about their museum social photography experiences at the Horniman Museum and Gardens in London.
In order to comprehensively explore and understand visitors’ social photographic behaviours in the museum visiting experience, mixed methods research was designed to explore this phenomenon from both quantitative and qualitative perspectives. Additionally, service design methods were employed to facilitate the research process, further interpret the collected dataset, and gain an in-depth understanding of this complex issue from a design perspective. Overall, the research findings revealed how and why visitors captured and shared these photographs to communicate information about their museum experiences, as well as what roles visitors’ social photography play in the museum experience. In the process of exploring visitors’ photographic engagement with museum context and with other visitors, the stakeholders and the complex online and offline interactions they formed within this museum experience were analysed and discussed. More importantly, by integrating different findings from quantitative and qualitative studies, a theoretical framework was proposed to coherently and systematically explain the correlation between social photography and the fundamental components that constitute a museum experience. Collectively, the research findings can be used to inform current museum practice and provide an alternative research approach for exploring social photography and museum experience related studies.
The effects of HIV type-1 viral suppression and non-viral factors on quantitative proteinuria in the highly active antiretroviral therapy era
Creators: name: Gupta, S.K.
name: Kalayjian, R.C.
name: Szczech, L.A.
name: Smurzynski, M.
name: Bosch, R.J.
name: Franceschini, N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Background: Proteinuria is associated with progressive renal disease and overall mortality in HIV-infected patients; however, the prevalence and correlates of quantitative proteinuria in the highly active antiretroviral therapy era are unknown. Methods: Spot urine protein to creatinine (P/Cr) ratios, an accepted measure of quantitative daily proteinuria, were measured annually since 2002 in participants of the AIDS Clinical Trials Group Longitudinal Linked Randomized Trials cohort. We used linear regression models with general estimating equations to identify factors associated with the abnormal P/Cr thresholds of ≥0.2 and ≥1.0. Results: Of the 2,857 participants (most of whom were receiving antiretroviral therapy) analysed, 16% and 3% had P/Cr levels ≥0.2 and ≥1.0, respectively, at first measurement. P/Cr levels did not change during a median follow-up of 3 years (interquartile range 2-4). Factors associated with P/Cr≥0.2 at any measurement included greater age, lower glomerular filtration rate, female sex. antiretroviral therapy prior to entry into parent randomized trial, HIV type-1 RNA level ≥400 copies/ml, lower CD4+ T-cell count and history of hypertension, diabetes or hepatitis C coinfection (all P<0.04). Black race and higher non-high-density lipoprotein cholesterol levels were associated with P/Cr levels ≥1.0. but not with P/Cr levels ≥0.2. Hepatitis B coinfection and current use of adefovir, indinavir and tenofovir were not associated with either of the P/Cr thresholds. Conclusions: Both HIV-1 and non-HIV-1 -related factors are associated with abnormal levels of proteinuria and identify those who are at a greater risk of worse clinical outcomes. Several of these factors are differentially associated with lower and higher proteinuria thresholds.
Kaposi's sarcoma-associated herpesvirus, but not Epstein-Barr virus, co-infection associates with coronavirus disease 2019 severity and outcome in South African patients.
Creators: name: Blumenthal, Melissa J
name: Lambarey, Humaira
name: Chetram, Abeen
name: Riou, Catherine
name: Wilkinson, Robert J
name: Schäfer, Georgia
name: Consortium, The HIATUS
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: subject: Model organisms
subject: Infectious Disease
subject: Human Biology & Physiology
subject: Immunology
subject: FOS: Clinical medicine

description: In South Africa, the Coronavirus Disease 2019 (COVID-19) pandemic is occurring against the backdrop of high Human Immunodeficiency Virus (HIV), tuberculosis and non-communicable disease burdens as well as prevalent herpesviruses infections such as Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV). As part of an observational study of adults admitted to Groote Schuur Hospital, Cape Town, South Africa during the period June-August 2020 and assessed for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, we measured KSHV serology and KSHV and EBV viral load (VL) in peripheral blood in relation to COVID-19 severity and outcome. A total of 104 patients with PCR-confirmed SARS-CoV-2 infection were included in this study. 61% were men and 39% women with a median age of 53 years (range 21-86). 29.8% (95% CI: 21.7-39.1%) of the cohort was HIV positive and 41.1% (95% CI: 31.6-51.1%) were KSHV seropositive. EBV VL was detectable in 84.4% (95% CI: 76.1-84.4%) of the cohort while KSHV DNA was detected in 20.6% (95% CI: 13.6-29.2%), with dual EBV/KSHV infection in 17.7% (95% CI: 11.1-26.2%). On enrollment, 48 [46.2% (95% CI: 36.8-55.7%)] COVID-19 patients were classified as severe on the WHO ordinal scale reflecting oxygen therapy and supportive care requirements and 30 of these patients [28.8% (95% CI: 20.8-38.0%)] later died. In COVID-19 patients, detectable KSHV VL was associated with death after adjusting for age, sex, HIV status and detectable EBV VL [p = 0.036, adjusted OR = 3.17 (95% CI: 1.08-9.32)]. Furthermore, in HIV negative COVID-19 patients, there was a trend indicating that KSHV VL may be related to COVID-19 disease severity [p = 0.054, unstandardized co-efficient 0.86 (95% CI: -0.015-1.74)] in addition to death [p = 0.008, adjusted OR = 7.34 (95% CI: 1.69-31.49)]. While the design of our study cannot distinguish if disease synergy exists between COVID-19 and KSHV nor if either viral infection is indeed fueling the other, these data point to a potential contribution of KSHV infection to COVID-19 outcome, or SARS-CoV-2 infection to KSHV reactivation, particularly in the South African context of high disease burden, that warrants further investigation.
Testing the CP-violating MSSM in stau decays at the LHC and ILC
Creators: name: Dreiner, Herbi
name: Kittel, Olaf
name: Kulkarni, Suchita
name: Marold, Anja
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study CP violation in the two-body decay of a scalar tau into a neutralino and a tau, which should be probed at the LHC and ILC. From the normal tau polarization, a CP asymmetry is defined which is sensitive to the CP phases of the trilinear scalar coupling parameter $A_τ$, the gaugino mass parameter $M_1$, and the higgsino mass parameter $μ$ in the stau-neutralino sector of the Minimal Supersymmetric Standard Model. Asymmetries of more than 70% are obtained in scenarios with strong stau mixing. As a result, detectable CP asymmetries in stau decays at the LHC are found, motivating further detailed experimental studies for probing the SUSY CP phases.
description: 14 pages, 7 figures, added references, corrected typos, revised figs.5b and 6a, physics unchanged
Universality of Asymptotically Ewens Measures on Partitions
Creators: name: Zhao, James Y.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60F05, 60C05

description: We introduce a universality theorem for functionals of measures on partitions which "behave like" the Ewens measure. Various limit theorems for the Ewens measure, most notably the Poisson-Dirichlet limit for the longest parts, the functional central limit theorem for the number of parts, and the Erdos-Turan limit for the product of parts, extend to these asymptotically Ewens measures as easy corollaries. Our major contributions are: (1) extending the classes of measures for which these limit theorems hold; (2) characterising universality by a single, easily-checked criterion; and (3) greatly shortening the proofs of the limit theorems using the Feller coupling.
title: La scuola di Roberto Sardelli (1968-1973). Documenti e testimonianze
Creators: name: Puglielli, Edoardo
Publisher: name: RomaTrE-Press
Year: 2021

description: Una “controscuola” del Sessantotto romano. Il volume ricostruisce l’esperienza pedagogica della «Scuola 725» (1968-1973), attivata a Roma nella baraccopoli dell’Acquedotto Felice da don Roberto Sardelli (1935-2019), esponente di rilievo del dissenso cattolico italiano degli anni Sessanta e Settanta del XX secolo. Sulla base degli studi esistenti e dell’analisi di fonti archivistiche e giornalistiche, alcune delle quali già pubblicate, altre ancora inedite, il volume ci restituisce un affresco delle vicende della «Scuola 725»: il ruolo che essa ha avuto nella formazione della coscienza critica e democratica dei giovani baraccati; le principali caratteristiche e finalità delle sue iniziative culturali e didattiche; la sua partecipazione alle lotte per il diritto alla casa e, più in generale, per l’universalizzazione e l’applicazione concreta dei diritti sociali e per il rispetto della dignità umana. Il volume riproduce anche documenti e testimonianze che consentono sia di approfondire il pensiero di Roberto Sardelli sia di presentare in maniera più efficace il contenuto etico e le attività della «Scuola 725».
N-fold integer programming in cubic time
Creators: name: Hemmecke, Raymond
name: Onn, Shmuel
name: Romanchuk, Lyubov
Publisher: name: arXiv
Year: 2011
Subjects: subject: Optimization and Control (math.OC)
subject: Discrete Mathematics (cs.DM)
subject: Data Structures and Algorithms (cs.DS)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 05A, 15A, 51M, 52A, 52B, 52C, 62H, 68Q, 68R, 68U, 68W, 90B, 90C

description: N-fold integer programming is a fundamental problem with a variety of natural applications in operations research and statistics. Moreover, it is universal and provides a new, variable-dimension, parametrization of all of integer programming. The fastest algorithm for $n$-fold integer programming predating the present article runs in time $O(n^{g(A)}L)$ with $L$ the binary length of the numerical part of the input and $g(A)$ the so-called Graver complexity of the bimatrix $A$ defining the system. In this article we provide a drastic improvement and establish an algorithm which runs in time $O(n^3 L)$ having cubic dependency on $n$ regardless of the bimatrix $A$. Our algorithm can be extended to separable convex piecewise affine objectives as well, and also to systems defined by bimatrices with variable entries. Moreover, it can be used to define a hierarchy of approximations for any integer programming problem.
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title: Design asinhronisations synchronous generator for a wind power plant with a capacity of 3.5 MW
Creators: name: ÐÑÑÐ·ÐµÐ²Ð°, ÐÐ»ÑÐ³Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
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description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ Ð°ÑÐ¸Ð½ÑÑÐ¾Ð½Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¹ ÑÐ¸Ð½ÑÑÐ¾Ð½Ð½ÑÐ¹ Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾Ñ (ÐÐ¡Ð) Ð´Ð»Ñ Ð²ÐµÑÑÐ¾ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐ¸ (ÐÐ­Ð£).
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description: The object of development and research is an asynchronous synchronous generator (ASG) for a wind power plant. The purpose of work â design and calculation of characteristics of ASG. In this paper we consider different types of generators used for wind turbines. The analysis of their characteristics and the rationale for the choice of ACG as the main element of the electrical network wind power plant. On the basis of the terms of reference for the methods of calculation of Kopylov I. P. and Sergeev P. S., an asynchronous synchronous generator for a wind power plant with a capacity of 3.5 MW and the main modes of operation is calculated. In addition, the calculation models of the generator are constructed using The Elcut software complex.
O Evento de Tunguska de 1908 nos registos do Observatório Geofísico e Astronómico da Universidade de Coimbra
Creators: name: Lopes, Fernando C.
name: Gomes, Ana I.
name: Ribeiro, Paulo
name: Alves, Eduardo I.
Publisher: name: Zenodo
Year: 2020

description: A explosão de Tunguska, que ocorreu na Sibéria Central na manhã do dia 30 de junho de 1908 (cerca das 0 h 13 min, hora GMT), devastou uma grande área de floresta e desencadeou importantes perturbações geofísicas, meteorológicas e biológicas. Em diversos locais da Eurásia setentrional e central foram registados abalos sísmicos, flutuações na pressão atmosférica e anomalias no campo geomagnético. Nesta época, faziam-se observações magnéticas, meteorológicas e sísmicas no Observatório Meteorológico e Magnético da Universidade de Coimbra (OMMUC). Neste trabalho, procedeu-se à análise dos registos sísmicos e magnéticos pertencentes ao espólio histórico do antigo OMMUC, com o objetivo de identificar qualquer perturbação que pudesse ser atribuída ao Evento de Tunguska. Foi possível concluir que a vibração sísmica provocada pela explosão de Tunguska foi registada, o mesmo não acontecendo com a perturbação geomagnética.
N2, Porta Ovest – Rotonda Val Gersa
Creators: name: Broggi, Martino
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2023

description: Il lavoro di tesi tratta il riordino stradale previsto nella bretella che dallo svincolo di Lugano Nord permette l'accesso al comune di Massagno e alla quale si accede invece da Savosa. Nell’avanzamento delle fasi si entrerà nel dettaglio della progettazione della rotonda Val Gersa, ovvero l’elemento principale che permetterà il riordino di quest’area.
Deep, Wide-field CCD Photometry for the Open Cluster NGC3532
Creators: name: Clem, James L.
name: Landolt, Arlo U.
name: Hoard, D. W.
name: Wachter, Stefanie
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the results of a deep, wide-field CCD survey for the open cluster NGC~3532. Our new $BV(RI)_{c}$ photometry effectively covers a one square degree area and reaches an unprecedented depth of $V\sim21$ to reveal that NGC~3532 is a rich open cluster that harbors a large number of faint, low-mass stars. We employ a number of methods to reduce the impact of field star contamination in the cluster color-magnitude diagrams, including supplementing our photometry with $JHK_{s}$ data from the 2MASS catalog. These efforts allow us to define a robust sample of candidate main sequence stars suitable for a purely empirical determination of the cluster's parameters by comparing them to the well-established Hyades main sequence. Our results confirm previous findings that NGC~3532 lies fairly near to the Sun [$(m-M)_0=8.46\pm0.05$; $492^{+12}_{-11}$~pc] and has an extremely low reddening for its location near the Galactic plane [$E(B-V)=0.028\pm0.006$]. Moreover, an age of $\sim300$\,Myr has been derived for the cluster by fitting a set of overshooting isochrones to the well-populated upper main-sequence. This new photometry also extends faint enough to reach the cluster white dwarf sequence, as confirmed by our photometric recovery of eight spectroscopically identified members of the cluster. Using the location of these eight members, along with the latest theoretical cooling tracks, we have identified $\sim30$ additional white dwarf stars in the $[V,~(B-V)]$ color-magnitude diagram that have a high probability of belonging to NGC~3532. The age we derive from fitting white dwarf isochrones to the locus of these stars, $300\pm100$\,Myr, is consistent with the age derived from the turnoff. Our analysis of the photometry also includes an estimation of the binary star fraction, as well as a determination of the cluster's luminosity and mass functions.
description: Accepted for publication in AJ. 55 pages, 21 figures. High-quality version with complete data tables can be downloaded from http://www.phys.lsu.edu/~jclem/NGC3532/
Cystatin C and preeclampsia: A case control study
Creators: name: Williams, M.A.
name: Qiu, C.
name: Barrow, D.A.
name: Franceschini, N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Pregnancy increases plasma cystatin C, but levels are much higher in preeclampsia. Previous studies have not quantified preeclampsia risk with varying cystatin C concentrations or adjusted for confounders. We performed a case-control study of 100 preeclampsia cases and 100 random pregnancies uncomplicated by hypertension (controls). All women were free of pre-existing hypertension, diabetes, and renal disease, and gave birth to singletons. Plasma cystatin C was measured at delivery. Adjusted odds ratios (OR) and 95% confidence intervals (CI) of preeclampsia by quartiles (based on control distribution) of maternal plasma cystatin C were estimated using multivariable logistic regression models. Mean cystatin C levels were elevated in preeclampsia cases compared with controls (1.38 ± 0.04 vs. 1.22 ± 0.03 mg/L, p < 0.01). Compared to the first quartile, the estimated risk of preeclampsia was increased by approximately 12-fold for the fourth quartile, after adjusting for maternal age, body mass index, physical inactivity, smoking, and gestational age. Increased plasma levels of cystatin C were independently associated with preeclampsia. Further studies are required to assess the role of cystatin C levels in preeclampsia severity and maternal and fetal outcomes.
Dynamic decision making in service operations management
Creators: name: Imanpoor Yourdshahy, Mona
Publisher: name: University of British Columbia
Year: 2020

description: This thesis comprises three studies. Within each study, we analyze a stochastic multi-period decision making problem in the area of service management. Throughout the dissertation, we incorporate dynamic programming techniques to develop the mathematical models and analyze the solution approaches for each of the discussed problems. In the first two studies, we consider a queueing system in which customers require some conditions to be met prior to receiving service. We investigate whether an individual arriving to this system should join the queue at that time, or wait to join at some future time. Chapters 2 and 3 discuss two variations of this problem. We formulate the problem as a Markov decision process and show how the structure of the optimal policy depends on various parameters of the model. Furthermore, in Chapter 3, we use the construct of “level-k” thinking from the behavioral and experimental economics literature to model the bounded rationality of customers, and also to characterize their equilibrium strategy. We present the structural results of the customers’ joining policies and show the threshold structure of customers’ decisions with different levels of rationality. We also analyze the socially optimal solution and compare it to the equilibrium policy. The optimal policies we derive allow for a better management of customers’ waiting time and also give information on their joining behavior to service providers. In the third study, we analyze another dynamic decision making problem in a different context than the previous two studies. Through tracking drivers’ behavior, Usage Based Insurance (UBI) allows insurance companies to connect insurers’ premiums more closely to their actual driving performance. Chapter 4 provides a theoretical model to capture the effects of UBI on the auto insurance market. We formulate the underlying problem as a dynamic principal-agent model with hidden information and hidden action. Developing a dynamic programming algorithm, we characterize the full history-dependent optimal contract. Our model results shed light on how to design the contract to manage a UBI program, the extent to which a UBI policy can outperform a traditional policy, and how the potential gains depend on the demographics of the target market.
TASK-BASED LEARNING VS TRADITIONAL GRAMMAR INSTRUCTION: A COMPARATIVE STUDY
Creators: name: Khujamkulov, Azizbek
name: Akhmedova, Muyassar
Publisher: name: Zenodo
Year: 2025

description: This think about investigates the adequacy of Task-Based Learning (TBL) in comparison to Conventional Language structure Instruction (TGI) in instructing outside dialects. Whereas TGI centers on unequivocal linguistic use rules and organized works out, TBL emphasizes communication and real-life assignments to create dialect capability. The inquire about analyzes how these approaches affect students' linguistic precision, familiarity, and inspiration. A comparative examination based on exploratory information from two learner bunches uncovers that TBL upgrades communicative competence and engagement, while TGI gives a solid establishment in linguistic rules but may restrain down to earth dialect utilize. The discoveries propose that an coordinates approach might maximize dialect securing benefits.
title: Ð¤Ð¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÑÐ¾Ð½ÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð½Ð°Ð²ÑÐºÐ¾Ð² ÑÐµÑÐ¸ Ñ Ð²Ð·ÑÐ¾ÑÐ»ÑÑ Ð¿ÑÐ¸ Ð¾Ð±ÑÑÐµÐ½Ð¸Ð¸ Ð¸Ð½Ð¾ÑÑÑÐ°Ð½Ð½Ð¾Ð¼Ñ ÑÐ·ÑÐºÑ (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ Ð°Ð½Ð³Ð»Ð¸Ð¹ÑÐºÐ¾Ð³Ð¾ Ð¸ Ð½ÐµÐ¼ÐµÑÐºÐ¾Ð³Ð¾ ÑÐ·ÑÐºÐ¾Ð²)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: The formation of phonetic speech skills in adults when teaching a foreign language (in English and German languages)
Creators: name: ÐÐ¼ÐµÐ»ÑÑÐµÐ½ÐºÐ¾, ÐÐ²Ð³ÐµÐ½Ð¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2022
Subjects: ÑÐ¾Ð½ÐµÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð½Ð°Ð²ÑÐºÐ¸ ÑÐµÑÐ¸
Ð´Ð¸ÑÑÐµÑÐµÐ½ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¹ Ð¿Ð¾Ð´Ñ Ð¾Ð´
Ð¸Ð¼Ð¸ÑÐ°ÑÐ¸Ð²Ð½ÑÐ¹ Ð¿Ð¾Ð´Ñ Ð¾Ð´
Ð¸Ð½Ð¾ÑÐ·ÑÑÐ½ÑÐ¹ ÑÐµÑÐµÐ²Ð¾Ð¹ ÑÐ»ÑÑ
Ð¿ÐµÑÑÐµÐ¿ÑÐ¸Ð²Ð½Ð°Ñ Ð±Ð°Ð·Ð°
phonetic speech skills
differentiated approach
imitative approach
foreign speech hearing
perceptual base

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¾Ð½ÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð½Ð°Ð²ÑÐºÐ¾Ð² Ñ Ð²Ð·ÑÐ¾ÑÐ»Ð¾Ð¹ Ð³ÑÑÐ¿Ð¿Ñ Ð¾Ð±ÑÑÐ°ÑÑÐ¸ÑÑÑ, Ð½Ðµ Ð¸Ð¼ÐµÑÑÐ¸Ñ ÑÐ¸ÑÑÐµÐ¼Ð½Ð¾Ð³Ð¾ Ð¾Ð¿ÑÑÐ° Ð² Ð¾Ð²Ð»Ð°Ð´ÐµÐ½Ð¸Ð¸ Ð¸Ð½Ð¾ÑÑÑÐ°Ð½Ð½ÑÐ¼ ÑÐ·ÑÐºÐ¾Ð¼ Ð¸ Ð¸Ð·ÑÑÐ°ÑÑÐ¸Ñ ÑÐ·ÑÐº Ð² ÑÐ°Ð¼ÐºÐ°Ñ Ð´Ð¾Ð¿Ð¾Ð»Ð½Ð¸ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ. ÐÐ°Ð½Ñ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÐµ ÑÐ¾ÑÐ¼ÑÐ»Ð¸ÑÐ¾Ð²ÐºÐ¸ Ð¿Ð¾Ð½ÑÑÐ¸Ñ ÑÐ¾Ð½ÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð½Ð°Ð²ÑÐºÐ¾Ð² ÑÐµÑÐ¸, Ð° ÑÐ°ÐºÐ¶Ðµ Ð¾ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸Ð·Ð¾Ð²Ð°Ð½Ñ ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ðµ Ð¿Ð¾Ð´ÑÐ¾Ð´Ñ Ðº Ð¸Ñ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ. ÐÐ·ÑÑÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð²Ð¸Ð´Ñ ÑÐ¿ÑÐ°Ð¶Ð½ÐµÐ½Ð¸Ð¹, Ð²Ð»Ð¸ÑÐ½Ð¸Ðµ ÑÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾ÑÑÐ¸ Ð¸Ð½Ð¾ÑÐ·ÑÑÐ½Ð¾Ð³Ð¾ ÑÐµÑÐµÐ²Ð¾Ð³Ð¾ ÑÐ»ÑÑÐ° Ð½Ð° ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ ÑÐ¾Ð½ÐµÑÐ¸ÑÐµÑÐºÐ¸Ð¼ Ð½Ð°Ð²ÑÐºÐ°Ð¼, Ð° ÑÐ°ÐºÐ¶Ðµ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð° ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ° Ð²Ð·ÑÐ¾ÑÐ»ÑÑ ÐºÐ°Ðº Ð¾ÑÐ¾Ð±Ð¾Ð¹ Ð²Ð¾Ð·ÑÐ°ÑÑÐ½Ð¾Ð¹ Ð³ÑÑÐ¿Ð¿Ñ Ð¾Ð±ÑÑÐ°ÑÑÐ¸ÑÑÑ. Ð ÑÐ°Ð¼ÐºÐ°Ñ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ ÑÐ¿ÑÐ°Ð¶Ð½ÐµÐ½Ð¸Ñ Ð´Ð»Ñ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ ÑÐ¾Ð½ÐµÑÐ¸ÐºÐµ Ð°Ð½Ð³Ð»Ð¸Ð¹ÑÐºÐ¾Ð³Ð¾ Ð¸ Ð½ÐµÐ¼ÐµÑÐºÐ¾Ð³Ð¾ ÑÐ·ÑÐºÐ° Ñ ÑÑÐµÑÐ¾Ð¼ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐµÐ¹ Ð²Ð·ÑÐ¾ÑÐ»Ð¾Ð¹ Ð°ÑÐ´Ð¸ÑÐ¾ÑÐ¸Ð¸.
description: The work discusses the acquisition of phonetic skills by adult learners who have no full-fledged experience in learning a foreign language and are learning it on the basis of additional education programs. The work considers different definitions of phonetic speech skills and characterizes current approaches to their development. It looks at the main types of exercises in this field as well as the influence of foreign speech hearing skills on the effective training of phonetic skills. The work describes the characteristics of adults as a specific age group of students. Practical research includes exercises devised for teaching phonetics in English and German, given the distinctions of adult learners.Â
Constructing a bivariate distribution function with given marginals and correlation: application to the galaxy luminosity function
Creators: name: Takeuchi, Tsutomu T.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We show an analytic method to construct a bivariate distribution function (DF) with given marginal distributions and correlation coefficient. We introduce a convenient mathematical tool, called a copula, to connect two DFs with any prescribed dependence structure. If the correlation of two variables is weak (Pearson's correlation coefficient $|ρ| <1/3 $), the Farlie-Gumbel-Morgenstern (FGM) copula provides an intuitive and natural way for constructing such a bivariate DF. When the linear correlation is stronger, the FGM copula cannot work anymore. In this case, we propose to use a Gaussian copula, which connects two given marginals and directly related to the linear correlation coefficient between two variables. Using the copulas, we constructed the BLFs and discuss its statistical properties. Especially, we focused on the FUV--FIR BLF, since these two luminosities are related to the star formation (SF) activity. Though both the FUV and FIR are related to the SF activity, the univariate LFs have a very different functional form: former is well described by the Schechter function whilst the latter has a much more extended power-law like luminous end. We constructed the FUV-FIR BLFs by the FGM and Gaussian copulas with different strength of correlation, and examined their statistical properties. Then, we discuss some further possible applications of the BLF: the problem of a multiband flux-limited sample selection, the construction of the SF rate (SFR) function, and the construction of the stellar mass of galaxies ($M_*$)--specific SFR ($SFR/M_*$) relation. The copulas turned out to be a very useful tool to investigate all these issues, especially for including the complicated selection effects.
description: 14 pages, 5 figures, accepted for publication in MNRAS.
Stochastic dynamics of N bistable elements with global time-delayed interactions: towards an exact solution of the master equations for finite N
Creators: name: Kimizuka, M.
name: Munakata, T.
name: Rosinberg, M. L.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider a network of N noisy bistable elements with global time-delayed couplings. In a two-state description, where elements are represented by Ising spins, the collective dynamics is described by an infinite hierarchy of coupled master equations which was solved at the mean-field level in the thermodynamic limit. For a finite number of elements, an analytical description was deemed so far intractable and numerical studies seemed to be necessary. In this paper we consider the case of two interacting elements and show that a partial analytical description of the stationary state is possible if the stochastic process is time-symmetric. This requires some relationship between the transition rates to be satisfied.
description: 17 pages, 7 figures
Explicity birational geometry of Fano 3-folds of high index
Creators: name: Duarte Guerreiro, Tiago
Publisher: name: Loughborough University
Year: 2022
Subjects: subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: We complete the analysis on the birational rigidity of quasismooth Fano 3-fold deformation families appearing in the Graded Ring Database as a complete intersection. When such a deformation family X has Fano index at least 2 and is minimally embedded in a weighted projective space in codimension 2, we determine which cyclic quotient singularity is a maximal centre. If a cyclic quotient singularity is a maximal centre, we construct a Sarkisov link to a non-isomorphic Mori fibre space or a birational involution. We define linear cyclic quotient singularities on X and prove that these are maximal centres by explicitly computing Sarkisov links centred at them. It turns out that each X has a linear cyclic quotient singularity leading to a new birational model. As a consequence, we show that if X is birationally rigid then its Fano index is 1. If the new birational model is a strict Mori fibre space, we determine its fibration type explicitly. In this case, a general member of X is birational to a del Pezzo fibration of degrees 1, 2 or 3 or to a conic bundle Y/S where S is a weighted projective plane with at most A2 singularities.
Short-Wave Excitations in Non-Local Gross-Pitaevskii Model
Creators: name: Ivashin, A. P.
name: Poluektov, Yu. M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: It is shown, that a non-local form of the Gross-Pitaevskii equation allows to describe not only the long-wave excitations, but also the short-wave ones in the systems with Bose-condensate. At given parameter values, the excitation spectrum mimics the Landau spectrum of quasi-particle excitations in superfluid Helium with roton minimum. The excitation wavelength, at which the roton minimum exists, is close to the inter-particle interaction range. It is shown, that the existence domain of the spectrum with a roton minimum is reduced, if one accounts for an inter-particle attraction.
description: 5 pages, 5 figures, UJP style; presented at Bogolyubov Kyiv Conference "Modern Problems of Theoretical and Mathematical Physics", September 15-18, 2009
LUNA: An algorithm for generating dynamic planet-moon transits
Creators: name: Kipping, David M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: It has been previously shown that moons of extrasolar planets may be detectable with the Kepler Mission, for moon masses above ~0.2 Earth masses Kipping et al. 2009c. Transit timing effects have been formerly identified as a potent tool to this end, exploiting the dynamics of the system. In this work, we explore the simulation of transit light curves of a planet plus a single moon including not only the transit timing effects but also the light curve signal of the moon itself. We introduce our new algorithm, LUNA, which produces transit light curves for both bodies, analytically accounting for shadow overlaps, stellar limb darkening and planet-moon dynamical motion. By building the dynamics into the core of LUNA, the routine automatically accounts for transit timing/duration variations and ingress/egress asymmetries for not only the planet, but also the moon. We then generate some artificial data for two feasibly detectable hypothetical systems of interest: a i) prograde and ii) retrograde Earth-like moon around a habitable-zone Neptune for a M-dwarf system. We fit the hypothetical systems using LUNA and demonstrate the feasibility of detecting these cases with Kepler photometry.
description: Accepted in MNRAS, 2011 May 16. Minor typos corrected (thanks to S. Awiphan)
Parallel evolution of a splicing program controlling neuronal excitability in flies and mammals.
Creators: name: Torres-Méndez, Antonio
name: Pop, Sinziana
name: Bonnal, Sophie
name: Almudi, Isabel
name: Avola, Alida
name: Roberts, Ruairí JV
name: Paolantoni, Chiara
name: Alcaina-Caro, Ana
name: Martín-Anduaga, Ane
name: Haussmann, Irmgard U
name: Morin, Violeta
name: Casares, Fernando
name: Soller, Matthias
name: Kadener, Sebastian
name: Roignant, Jean-Yves
name: Prieto-Godino, Lucia
name: Irimia, Manuel
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Imaging
subject: Genetics & Genomics
subject: Developmental Biology
subject: Ecology,Evolution & Ethology

description: Alternative splicing increases neuronal transcriptomic complexity throughout animal phylogeny. To delve into the mechanisms controlling the assembly and evolution of this regulatory layer, we characterized the neuronal microexon program in Drosophila and compared it with that of mammals. In nonvertebrate bilaterians, this splicing program is restricted to neurons by the posttranscriptional processing of the enhancer of microexons (eMIC) domain in Srrm234. In Drosophila, this processing is dependent on regulation by Elav/Fne. eMIC deficiency or misexpression leads to widespread neurological alterations largely emerging from impaired neuronal activity, as revealed by a combination of neuronal imaging experiments and cell type-specific rescues. These defects are associated with the genome-wide skipping of short neural exons, which are strongly enriched in ion channels. We found no overlap of eMIC-regulated exons between flies and mice, illustrating how ancient posttranscriptional programs can evolve independently in different phyla to affect distinct cellular modules while maintaining cell-type specificity.
Thermal Management con materiali polimerici modificati
Creators: name: Robbiani, Manuel
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2019

description: Il lavoro di tesi è incentrato sullo studio e l’analisi di polimeri termicamente conduttivi, in particolare sull’analisi dell’influenza dei diversi filler sul valore di conducibilità termica. Tale tecnologia permette la produzione di pezzi inizialmente pensati per essere composti in metallo o altri materiali e sostituirli con pezzi realizzati in polimero. Questo cambiamento oltre ad avere un’influenza sui costi di produzione ha il vantaggio di conferire a questi pezzi le caratteristiche delle materie plastiche. Il progetto si articola principalmente in due fasi: produzione dei compound con diversi additivi termicamente conduttivi e l’analisi dei compound tenendo conto delle caratteristiche termiche e strutturali dei filler. La prima fase è molto pratica in quanto si è estruso il compound con i due filler scelti, dopodiché il polimero caricato è stato stampato in piastre per poi poter ottenere dei provini tondi. Nella fase di analisi si è dapprima fatta una campagna di misure sperimentali della conducibilità termica dei provini per poi attraverso il l’utilizzo del software Design Expert eseguire lo studio del comportamento dei polimeri additivati così da poter correlare le proprietà termiche misurate con la microstruttura dei materiali.