cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Development of a microwave-assisted extraction of atropine and scopolamine from Solanaceae family plants followed by a QuEChERS cleanup procedure
Creators: name: Ciechomska, Monika
name: Michał Woźniakiewicz
name: Nowak, Julia
name: Świadek, Karolina
name: Bazylewicz, Barbara
name: Paweł Kościelniak
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: In this work, a novel method based on the microwave-assisted extraction (MAE), the QuEChERS dispersive solid-phase extraction and gas chromatography–mass spectrometry was developed for the determination of atropine and scopolamine in plant samples from Datura and Brugmansia genera, which belong to the Solanaceae family. The experimental conditions for MAE, such as temperature, time of extraction, and volume of the extracting solvent as well as extract purification procedure parameters were optimized by the Doehlert uniform shell design and the response surface methodology. For quantitative analysis and validation, a standard addition calibration method was used to reduce the matrix effect. The limits of detection from 3.0 to 3.4 µg g−1 of dry matter and the linearity of the calibration dependence were suitable for the analysis of plant extracts. The repeatability and intermediate precision for both analytes were found to be acceptable (<15%). The developed method was successfully applied to the samples of leaves and seeds of Datura and Brugmansia.
title: 03_0355
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Development of a Microwave-Assisted Extraction of Atropine and Scopolamine From solanaceae family Plants Followed by a QuEChERS Clean-Up Procedure
Creators: name: Ciechomska, Monika
name: Michał Woźniakiewicz
name: Nowak, Julia
name: Świadek, Karolina
name: Bazylewicz, Barbara
name: Paweł Kościelniak
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Plant Biology

description: In this work, a novel method based on microwave-assisted extraction (MAE), the QuEChERS dispersive solid phase extraction and gas chromatography-mass spectrometry was developed for determination of atropine and scopolamine in plant samples from Datura and Brugmansia genera, which belong to the Solanaceae family. The experimental conditions for MAE, such as temperature, time of extraction and volume of the extracting solvent, as well as extract purification procedure parameters were optimized by the Doehlert uniform shell design and the response surface methodology. For quantitative analysis and validation, a standard addition calibration method was used in order to reduce the matrix effect. The limits of detection ranged from 3.0 to 3.4 µg g−1 of dry matter and the linearity of the calibration dependence was suitable for analysis of plant extracts. The repeatability and intermediate precision for both analytes was found to be acceptable (<15%). The developed method was successfully applied to samples of leaves and seeds of Datura and Brugmansia. Short Abstract: A novel method based on microwave-assisted extraction (MAE), the QuEChERS dispersive solid phase extraction and gas chromatography-mass spectrometry was developed for determination of atropine and scopolamine in plant samples from Datura and Brugmansia genera (Solanaceae family). The experimental conditions for MAE and QuEChERS extract purification procedure parameters were optimized by the Doehlert uniform shell design and the response surface methodology. For quantitative analysis and validation, a standard addition calibration method was used in order to reduce the matrix effect.
Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage checkpoint
Creators: name: Zheng, Kai
name: Li, Yan
name: Shaoxiang Wang
name: Wang, Xiao
name: Chenghui Liao
name: Xiaopeng Hu
name: Fan, Long
name: Qiangrong Kang
name: Zeng, Yong
name: Xuli Wu
name: Haiqiang Wu
name: Zhang, Jian
name: Yifei Wang
name: Zhendan He
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: Modulation of autophagy has been increasingly regarded as a promising cancer therapeutic approach. In this study, we screened several ginsenosides extracted from Panax ginseng and identified ginsenoside Ro (Ro) as a novel autophagy inhibitor. Ro blocked the autophagosome-lysosome fusion process by raising lysosomal pH and attenuating lysosomal cathepsin activity, resulting in the accumulation of the autophagosome marker MAP1LC3B/LC3B and SQSTM1/p62 (sequestosome 1) in various esophageal cancer cell lines. More detailed studies demonstrated that Ro activated ESR2 (estrogen receptor 2), which led to the activation of NCF1/p47PHOX (neutrophil cytosolic factor 1), a subunit of NADPH oxidase, and subsequent reactive oxygen species (ROS) production. Treatment with siRNAs or inhibitors of the ESR2-NCF1-ROS axis, such as N-acetyl-L-cysteine (NAC), diphenyleneiodonium chloride (DPI), apocynin (ACN), Tiron, and Fulvestrant apparently decreased Ro-induced LC3B-II, GFP-LC3B puncta, and SQSTM1, indicating that ROS instigates autophagic flux inhibition triggered by Ro. More importantly, suppression of autophagy by Ro sensitized 5-fluorouracil (5-Fu)-induced cell death in chemoresistant esophageal cancer cells. 5-Fu induced prosurvival autophagy, and by inhibiting such autophagy, siRNAs against BECN1/beclin 1, ATG5, ATG7, and LC3B enhanced 5-Fu-induced autophagy-associated and apoptosis-independent cell death. We observed that Ro potentiates 5-Fu cytotoxicity via delaying CHEK1 (checkpoint kinase 1) degradation and downregulating DNA replication process, resulting in the delayed DNA repair and the accumulation of DNA damage. In summary, these data suggest that Ro is a novel autophagy inhibitor and could function as a potent anticancer agent in combination therapy to overcome chemoresistance.
Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells
Creators: name: Li, Xu
name: Zhu, Feng
name: Jianxin Jiang
name: Chengyi Sun
name: Zhong, Qing
name: Shen, Ming
name: Wang, Xin
name: Tian, Rui
name: Chengjian Shi
name: Xu, Meng
name: Peng, Feng
name: Xingjun Guo
name: Hu, Jun
name: Dawei Ye
name: Wang, Min
name: Renyi Qin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology

description: In contrast to normal tissue, cancer cells display profound alterations in protein synthesis and degradation. Therefore, proteins that regulate endoplasmic reticulum (ER) homeostasis are being increasingly recognized as potential therapeutic targets. The ubiquitin-proteasome system and autophagy are crucially important for proteostasis in cells. However, interactions between autophagy, the proteasome, and ER stress pathways in cancer remain largely undefined. This study demonstrated that withaferin-A (WA), the biologically active withanolide extracted from Withania somnifera, significantly increased autophagosomes, but blocked the degradation of autophagic cargo by inhibiting SNARE-mediated fusion of autophagosomes and lysosomes in human pancreatic cancer (PC) cells. WA specifically induced proteasome inhibition and promoted the accumulation of ubiquitinated proteins, which resulted in ER stress-mediated apoptosis. Meanwhile, the impaired autophagy at early stage induced by WA was likely activated in response to ER stress. Importantly, combining WA with a series of ER stress aggravators enhanced apoptosis synergistically. WA was well tolerated in mice, and displayed synergism with ER stress aggravators to inhibit tumor growth in PC xenografts. Taken together, these findings indicate that simultaneous suppression of 2 key intracellular protein degradation systems rendered PC cells vulnerable to ER stress, which may represent an avenue for new therapeutic combinations for this disease.
Raisapoana parana Busck 2020
Creators: name: Austin, Kyhl A.
name: Dombroskie, Jason J.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Tortricidae
Raisapoana
Raisapoana parana

description:  Raisapoana parana (Busck), new combination ( Figs. 5, 6, 15, 17) Tortrix parana Busck, 1911: 228. " Archips " parana: Powell et al. 1995: 148 (new combination). [ Archipini unplaced] parana Brown 2005: 124. Additional material examined (2 ƠƠ, 4♀♀).— BRAZIL: 1Ơ, 1♀, Castro, Parana, E.D. Jones, 1892-5, 1912-534 ( Ơ with abdomen missing) ( BMNH). 1Ơ, Castro, Parana, Jones, 1898, 67377. KAA dissection #0155 ( BMNH). 1♀, Castro, Parana, Jones, 1898, 67376. British Museum GS #23477 [examined]. Wing venation slide #23477 [examined] ( BMNH). 1♀, Castro, Parana, Jones, 1896, 67524. KAA dissection #0156 ( BMNH). 1♀, same data as previous but 67535 ( BMNH). Discussion.— Tortrix parana Busck, 1911 is identical in forewing pattern ( Figs. 5, 6) to Raisapoana paraisoana Razowski and Becker, 2010. However, slight differences in the male genitalia suggest they are distinct species. Specifically, T. parana has an elongated crease-like structure extending from the ventroposterior corner of the valvae ( Fig. 15) that is absent in R. paraisoana. The phalli are similar, but T. parana possesses a well-developed caulis ( Fig. 15), while R. paraisoana does not. In addition, the type localities of these two species are 1200 km apart. The female of R. paraisoana is unknown.
description: Published as part of Austin, Kyhl A. & Dombroskie, Jason J., 2020, New Combinations In Neotropical Archipini And Atteriini (Lepidoptera: Tortricidae: Tortricinae), With The Description Of A New Genus, pp. 1-11 in Proceedings of the Entomological Society of Washington 122 (1) on pages 5-6, DOI: 10.4289/0013-8797.122.1.1In, http://zenodo.org/record/3724761
description: {"references": ["Busck, A. 1911. Descriptions of tineoid moths (Microlepidoptera) from South America. Proceedings of the United States National Museum 40: 205 - 231.", "Powell, J. A., J. Razowski, and J. W. Brown. 1995. Tortricidae: 138 - 157. In J. B. Heppner, ed. Atlas of Neotropical Lepidoptera. Checklist: Part 2 Hyblaeoidea-Pyraloidea-Tortricoidea: LIV + 243 pp. Association for Tropical Lepidoptera. Gainesville.", "Brown, J. W. 2005. World catalogue of insects. Volume 5. Tortricidae (Lepidoptera). Apollo Books, Stenstrup. 1 - 742.", "Razowski, J. and V. O. Becker. 2010. Systematic and distributional data on Neotropical Ar- chipini (Lepidoptera: Tortricidae). Acta Zoologica Cracoviensia 53 B (1 - 2): 9 - 38."]}
title: 01_1911
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Autophagy proteins are not universally required for phagosome maturation
Creators: name: Cemma, Marija
name: Grinstein, Sergio
name: Brumell, John H.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Phagocytosis plays a central role in immunity and tissue homeostasis. After internalization of cargo into single-membrane phagosomes, these compartments undergo a maturation sequences that terminates in lysosome fusion and cargo degradation. Components of the autophagy pathway have recently been linked to phagosome maturation in a process called LC3-associated phagocytosis (LAP). In this process, autophagy machinery is thought to conjugate LC3 directly onto the phagosomal membrane to promote lysosome fusion. However, a recent study has suggested that ATG proteins may in fact impair phagosome maturation to promote antigen presentation. Here, we examined the impact of ATG proteins on phagosome maturation in murine cells using FCGR2A/FcγR-dependent phagocytosis as a model. We show that phagosome maturation is not affected in Atg5-deficient mouse embryonic fibroblasts, or in Atg5- or Atg7-deficient bone marrow-derived macrophages using standard assays of phagosome maturation. We propose that ATG proteins may be required for phagosome maturation under some conditions, but are not universally required for this process.
Autophagy Proteins are not Universally Required for Phagosome Maturation
Creators: name: Cemma, Marija
name: Grinstein, Sergio
name: Brumell, John H.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Phagocytosis plays a central role in immunity and tissue homeostasis. After internalization of cargo into single-membrane phagosomes, these compartments undergo a maturation sequences that terminates in lysosome fusion and cargo degradation. Components of the autophagy pathway have recently been linked to phagosome maturation in a process called LC3-associated phagocytosis (LAP). In this process, autophagy machinery is thought to conjugate LC3 directly onto the phagosomal membrane to promote lysosome fusion. However, a recent study has suggested that ATG proteins may in fact impair phagosome maturation to promote antigen presentation. Here, we examined the impact of ATG proteins on phagosome maturation in murine cells using FCGR2A/FcγR-dependent phagocytosis as a model. We show that phagosome maturation is not affected in Atg5-deficient mouse embryonic fibroblasts, or in Atg5- or Atg7-deficient bone marrow-derived macrophages using standard assays of phagosome maturation. We propose that ATG proteins may be required for phagosome maturation under some conditions, but are not universally required for this process.
title: Restoration or degradation
title: exotic grass management and ecosystem dynamics in Australia's tropical savannas
titleType: Subtitle
Creators: name: Brooks, Kristine
Publisher: name: Charles Darwin University
Year: 2010

description: Introduced grasses have been associated with the transformation of ecosystem structure and function in the tropical savanna woodlands of Australia and South America. Consequently, there has been considerable research on the process and impacts of exotic grass invasion. However, little attention has been paid to the management of these grasses and how it affects the successional trajectory of savanna systems. Management of invasive species can have unexpected outcomes due to invasion induced changes to the system and through the impacts of the management action itself. Removal of the invasive species can be a large biotic change that, if poorly considered, could be responsible for creating positive feedbacks that promote further degradation. Consequently, methods used to remove invasive species have the potential to cause biotic and abiotic degradation, even when the invasion process itself may not. In Australia's tropical savannas, Andropogon gayanus Kunth. (gamba grass) and Pennisetum polystachion L. Schult. (perennial mission grass) are increasingly the focus of intensive management programs. This is motivated by the rapid spread of both exotic grasses into a range of habitats in disturbed and undisturbed savanna and their potential to alter fire regimes and nutrient cycling. However, empirical information on the effects of widely accepted exotic grass management techniques on the tropical savannas of north Australia has not been documented. Therefore, this thesis focuses on an important aspect of invasive species management in the savannas the impact of exotic grasses and their management on the potential for restoration in the savanna woodland.
title: Préface_Les principaux trouvères de la Champagne et de la Brie, suivis d'un fabliau - le Jongleur de Sens chez Lucifer, 1150-1350
Creators: name: AmateurS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021

description: Préface
description: ID_PARA_01015
Autophagy regulates spermatid differentiation via degradation of PDLIM1
Creators: name: Yongliang Shang
name: Hongna Wang
name: Pengfei Jia
name: Haichao Zhao
name: Liu, Chao
name: Weixiao Liu
name: Zhenhua Song
name: Zhiliang Xu
name: Yang, Lin
name: Yanfang Wang
name: Li, Wei
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Spermiogenesis is a complex and highly ordered spermatid differentiation process that requires reorganization of cellular structures. We have previously found that Atg7 is required for acrosome biogenesis. Here, we show that autophagy regulates the round and elongating spermatids. Specifically, we found that Atg7 is required for spermatozoa flagella biogenesis and cytoplasm removal during spermiogenesis. Spermatozoa motility of atg7-null mice dropped significantly with some extra-cytoplasm retained on the mature sperm head. These defects are associated with an impairment of the cytoskeleton organization. Functional screening revealed that the negative cytoskeleton organization regulator, PDLIM1 (PDZ and LIM domain 1 [elfin]), needs to be degraded by the autophagy-lysosome-dependent pathway to facilitate the proper organization of the cytoskeleton. Our results thus provide a novel mechanism showing that autophagy regulates cytoskeleton organization mainly via degradation of PDLIM1 to facilitate the differentiation of spermatids.
A Central Auditory Test reveals differences between drug treatment regimens in adults living with HIV
Creators: name: Niemczak, Christopher E.
name: Zhan, Yi
name: Ren, Junkun
name: Song, Fengxiang
name: Lu, Hongzhou
name: Chen, Guochao
name: Fellows, Abigail M.
name: Gui, Jiang
name: Soli, Sigfrid D.
name: Buckey, Jay C.
name: Shi, Yuxin
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Medicine
Neuroscience
Biotechnology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Science Policy
Mental Health

description: This exploratory study examined whether central auditory tests show differences between people living with HIV (PLWH) treated with two predominant antiretroviral drug therapy (ART) regimens. Cross-sectional. 253 PLWH (mean age 39.8 years) from the Shanghai Public Health Clinical Centre, China. The Hearing in Noise Test speech reception threshold (SRT) assessed central auditory function and the Montreal Cognitive Assessment (MoCA) assessed cognition. The relationship between ART regimen and SRT was evaluated with multivariable linear regression incorporating age, HIV duration, and peripheral hearing ability. Multivariable logistic regression was used to ascertain if SRT and ART regimen predicted MoCA impairment. The two predominant ART regimens differed by one drug (zidovudine or tenofovir). Participants taking the zidovudine-containing regimen had poorer SRT performance (p=.012) independent of age and hearing thresholds. MoCA scores did not differ between drug regimens, but a negative relationship was found between SRT and MoCA impairment (p=.048). ART regimens differed in their association with central auditory test performance likely reflecting neurocognitive changes in PLWH taking the zidovudine-containing regimen. Central auditory test performance also marginally predicted cognitive impairment, supporting further assessment of central auditory tests to detect neurocognitive deficits in PLWH.
A scoping review exploring how adults self-describe and communicate about the listening difficulties they experience
Creators: name: McNeice, Zoe
name: Tomlin, Dani
name: Timmer, Barbra
name: Short, Camille E
name: Nixon, Grace
name: Galvin, Karyn
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Marine Biology
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences

description: Objective: It is unknown how adults communicate about their experienced listening difficulties with their audiologist. This scoping review aims to explore how adults self-describe the listening difficulties that they experience, and how they communicate about them. Design: A scoping review was conducted between December 2020 and September 2022 to identify published journal articles in which adults described and communicated about their listening difficulties. Study sample: Database searches yielded 10,224 articles initially. After abstract screening and full text review, 55 articles were included for analysis. Results: The listening difficulties that adults described were varied, highlighting the fact that each person has individual experiences. Adults discussed reasons for their listening difficulties, impacts of their listening difficulties, and behavioural responses they adopted to cope with their listening difficulties. Conclusions: This review shows the broad impacts of listening difficulties, and the varied ways in which adults discuss their listening difficulties. There is no available literature reporting how adults communicate about their listening difficulties in a clinical context.
Обзор рекомендаций по ведению беременных с COVID19: что должен знать акушерский анестезиолог
Creators: name: Шифман Е. М.
name: Иоскович А. М.
name: Роненсон Александр Михайлович
name: Куликов А. В.
Publisher: name: Вестник акушерской анестезиологии
Year: 2020
Subjects: беременность
COVID19
анестезия

description: Уважаемые коллеги! В связи с неблагоприятной эпидемиологической обстановкой в мире мы решили посвятить этот номер важной информации для анестезиологов-реаниматологов, акушеров-гинекологов и всех врачей, которым, возможно, предстоит работать с беременными, пораженными вирусом COVID19. Стоит отметить, что информация о заболеваемости и смертности от вируса обновляется ежечасно, поэтому уследить за самыми последними тенденциями в профилактике, диагностике, лечении и анестезиологическом обеспечении рожениц с COVID19 довольно сложно. Однако мы постарались собрать для вас всю самую свежую и последнюю информацию, касающуюся анестезиологического обеспечения беременных с COVID19.
title: Über den Sümpfen. Norbert Randow nachgerufen
Creators: name: Weiler, Thomas
Publisher: name: Fachinformationsdienst Slavistik
Year: 2016
Subjects: subject: Randow, Norbert
subject: Belarussisch
subject: Deutsch
subject: Übersetzer
subject: 491.8

description: „Norbert Randow hat an Grenzen gelebt und an Grenzen gearbeitet. Und er beherrscht die Kunst – ohne Verlust an Eigenart – zwischen Fremden, zwischen Welten zu vermitteln. Er versteht es, Bücher zu Grenzübertritten zu fördern.“ So pries Fedja Filkova den Träger des Leipziger Anerkennungspreises zur europäischen Verständigung 2001 in ihrer Laudatio. Am 1. Oktober 2013 hat er die letzte Grenze überschritten.
description: novinkivorgestellt
A comparison of the impact of the COVID-19 pandemic on communication among individuals with and without hearing impairment
Creators: name: Jansen, Lotte A.
name: van Wier, Marieke F.
name: Lissenberg-Witte, Birgit I.
name: Kramer, Sophia E.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Objective: This study assessed the impact of coronavirus disease-2019 (COVID-19) preventative measures on hearing and communication among individuals with normal and impaired hearing. We also evaluated the use of digital communication tools between these groups. Design: For this cross-sectional study, participants completed an online digits-in-noise test and survey. Survey topics included understanding through masks, behind plastic screens, from a 1.5-m distance, and use of social network sites/apps, direct messaging, and video calling. Logistic regressions assessed the odds of disagreeing versus agreeing with survey statements. Study Sample: A total of 880 adults from the National Longitudinal Study on Hearing completed a survey and hearing test. Based on speech reception threshold scores, participants were categorised into “good” (reference group for all analyses), “insufficient”, or “poor” hearing groups. Results: Those with insufficient and poor hearing had more difficulty understanding others through facemasks, plastic screens, and from 1.5 m. Those with poor hearing had a higher odds of video calling more to contact family/friends/acquaintances during the pandemic, but also had more difficulty hearing sufficiently through video calls. Conclusions: This study addresses methodological weaknesses in previous studies. Results strengthen current evidence of the burden COVID-19 measures place on individuals with hearing impairment.
How people with tinnitus-related insomnia experience group CBT-for-insomnia (CBTi): a thematic analysis
Creators: name: Cramer, Lavinia
name: Vogt, Florian
name: McKenna, Laurence
name: Marks, Elizabeth
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Objective: Although insomnia often compounds tinnitus, sleeping problems in people experiencing tinnitus are rarely treated. This study investigates the experiences of participants receiving Cognitive Behavioural Therapy for insomnia (CBTi) as part of a randomised controlled trial for managing tinnitus-related insomnia. The aim of this study is to gain detailed insight into participants’ perceptions and experiences of this treatment. Design: Semi-structured interviews were conducted via phone or in-person by one of the two clinical psychologists who facilitated the CBTi sessions. Reflexive thematic analysis with semantic inductive approach was used for analysis to keep the research question theoretically flexible. Study samples: Eight participants (three females, age range 32–69 years) were interviewed six months after CBTi completion. Results: Three superordinate themes were identified: “Common humanity and transcending individual distress,” “Changing the things I can” and “Accepting the things I cannot change.” The group environment helped participants to normalise their experiences. Reliable tinnitus/sleep information and robust behavioural change techniques helped participants to respond and relate to their condition differently. Conclusion: Generally, participants reported long-term benefits from CBTi to treat tinnitus-related insomnia, particularly increased confidence, and getting on with life. CBTi is multi-component, so clinicians need to respond to individual preferences and lifestyles.
ПРОБЛЕМЫ СОВРЕМЕННОЙ ПОСЛЕОПЕРАЦИОННОЙ АНАЛЬГЕЗИИ В АКУШЕРСТВЕ И ПУТИ ИХ РЕШЕНИЯ
Creators: name: Винокурова Анна Анатольевна
name: Дубровин С. Г.
name: Руднов В. А.
Publisher: name: Вестник акушерской анестезиологии
Year: 2020
Subjects: послеоперационная анальгезия
обезболивание
кесарево сечение
безопиоидная анальгезия

description: В данном обзоре дана оценка основным современным методам послеоперационной анальгезии в акушерстве с позиции клинической эффективности, безопасности, простоты и удобства применения в рутинной практике. Также приводятся рекомендации в отношении оформления документации при использовании техник и препаратов «off-label» с учетом современного Российского законодательства.
Glass-Eel-Stage American Eels Respond to Conspecific Odor as a Function of Concentration
Creators: name: Schmucker, Andrew K.
name: Johnson, Nicholas S.
name: Galbraith, Heather S.
name: Weiming Li
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: The American Eel Anguilla rostrata has experienced staggering population declines in recent decades and is now the focus of restoration efforts. Studies have demonstrated that olfaction is critical to anguillid behavior and that glass eels (the life stage which migrates inland from saltwater to freshwater) are attracted to conspecific washings. We evaluated conspecific cueing as a potential mechanism for American Eel inland migration coordination by assessing (1) the affinity of glass eels to conspecific washings, (2) the concentration–response relationships, and (3) changes in responsiveness to washings during the glass eel-to-elver transition. In two-choice maze assays, glass eels were attracted to glass eel washings over a wide range of concentrations (0.20–0.40 g of glass eels·L−1·h−1), and a logarithmic function provided the best fit to the concentration–response relationship. When given a choice between two conspecific washings of higher and lower concentrations, the glass eels generally preferred the higher concentration. Responses to undiluted glass eel washings did not significantly differ among stage-3–7 glass eels, although stage-7 eels were not attracted to the washings, whereas the other stages were. Washing affinity remained similar over the course of several weeks. These results support aspects of the conspecific cueing hypothesis at the glass eel life stage under laboratory conditions, suggesting that conspecific cueing is an important component of migration coordination among juvenile American Eels and warrants additional study. Received September 11, 2015; accepted January 20, 2016 Published online June 15, 2016
The integrin αv-TGFβ signaling axis is necessary for epidermal proliferation during cutaneous wound healing
Creators: name: Duperret, Elizabeth K.
name: Natale, Christopher A.
name: Monteleon, Christine
name: Dahal, Ankit
name: Ridky, Todd W.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Proliferation and migration of epidermal keratinocytes are essential for proper cutaneous wound closure after injury. αv integrins and several of their ligands—vitronectin, TGFβ and thrombospondin—are up-regulated in healing wounds. However, the role of αv integrins in wound re-epithelialization is unknown. Here, we show that genetic depletion or antibody-mediated blockade of pan-integrin αv, or the specific heterodimer αvβ6, in keratinocytes limited epidermal proliferation at the wound edge and prevented re-epithelialization of wounded human organotypic skin both in vivo and in vitro. While we did not observe a migration defect upon αv blockade in vivo, αv was necessary for keratinocyte migration over longer distances in organotypic skin. Integrin αv is required for local activation of latent TGFβ, and the wound healing defect in the setting of integrin αv loss was rescued by exogenous, active TGFβ, indicating that the αv-TGFβ signaling axis is a critical component of the normal epidermal wound healing program. As chronic wounds are associated with decreased TGFβ signaling, restoration of TGFβ activity may have therapeutic utility in some clinical settings.
1-(5-Carboxyindazol-1-yl)propan-2-ones as dual inhibitors of cytosolic phospholipase A2α and fatty acid amide hydrolase: bioisosteric replacement of the carboxylic acid moiety
Creators: name: Althaus, Jan
name: Hake, Theresa
name: Hanekamp, Walburga
name: Lehr, Matthias
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Indazole-5-carboxylic acids with 3-aryloxy-2-oxopropyl residues in position 1 were previously reported to be potent dual inhibitors of cytosolic phospholipase A2α (cPLA2α) and fatty acid amide hydrolase (FAAH). In continuation of our structure-activity studies on cPLA2α and FAAH inhibitors, a number of derivatives of these substances characterized by bioisosteric replacement of the carboxylic acid functionality by inverse amides, sulfonylamides, carbamates and ureas were prepared. The biological evaluation of the obtained compounds showed that the carboxylic acid functionality of the lead compounds is of special importance for a pronounced inhibition of cPLA2α and FAAH.
Intervenir contre le gré du patient : médication PRN et vécu phénoménologique du personnel infirmier exerçant en milieu psycho-légal
Creators: name: Seyer-Forget, Charlène
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2020
Subjects: Contrôle
PRN
Sécurité
Psycho-légal
Phénoménologie
Infirmière

description: Ce projet de recherche de maîtrise s’inscrit dans une recherche d’envergure s’intitulant Treatment or Control : Toward a Phenomenological Understanding of the Use of Chemical Restraints in Mental Health Care conduite par les professeurs Dave Holmes, Jean Daniel Jacob, Emmanuelle Bernheim et M. Étienne Paradis-Gagné dans laquelle la perspective des patients et du personnel infirmier a été explorée. Cette thèse de maîtrise s’attarde spécifiquement au vécu du personnel infirmier d’un hôpital psycho-légal canadien qui doit répondre quotidiennement à des impératifs cliniques, déontologiques et légaux à l’intersection du système de santé et du système de justice. L’objectif est d’explorer leur vécu au moment d’intervenir avec un médicament PRN administré contre le gré du patient. Grâce à l’analyse interprétative phénoménologique, le vécu de 14 infirmières d’un milieu psycho-légal de sécurité maximum a été exploré au moment d’intervenir avec un PRN contre le gré du patient. Le cadre théorique s’appuie sur l’anatomo-politique de Foucault (1975) et celui de la nature des relations dans les institutions totales de Goffman (1968). Nos résultats montrent que l’infirmière (la profession infirmière) doit engager simultanément son allégeance au patient (système de santé), au système de justice et à la culture de l’institution totale. Les allégeances multiples génèrent des paradoxes qui affectent la manière dont l’infirmière actualise son rôle professionnel et est en mesure de prodiguer des soins selon les normes établies au moment d’administrer un PRN contre le gré du patient. L’infirmière doit apprendre à composer avec ces paradoxes pour soigner cette clientèle pour laquelle le cadre légal, l’approche éthique et les connaissances cliniques répondent de manière imparfaite tout au mieux au carrefour de deux systèmes. Une éthique du corps-vécu est discutée dans une perspective critique à la recherche d’une voie pour aider à concilier les impératifs des deux systèmes pour les infirmières œuvrant en milieu psycho-légal.
Impacts of the Value-Added Producer Grant Program on Business Outcomes
Creators: name: Rupasingha, Anil
name: Pender, John
name: Rupasingha, Anil
name: Pender, John
Publisher: name: Unknown
Year: 2018
Subjects: subject: Agricultural and Food Policy
subject: Agricultural Finance
subject: Farm Management
subject: Financial Economics
subject: Marketing
subject: FOS: Economics and business
subject: small businesses
subject: Value-Added Producer Grant (VAPG)

description: The Value-Added Producer Grant (VAPG) program provides grants to help farmers and ranchers add greater value for agricultural commodities, such as through additional processing or marketing of new products. Between 2001 and 2015, the program provided a total of 2,345 grants to farmers and ranchers—a total value of $318 million, or about $136,000 per grant on average.
Monitoring cognitive and psychological changes for indigenous Australians following petrol and alcohol abuse
Creators: name: Dingwall, Kylie
Publisher: name: Charles Darwin University
Year: 2010

description: The current research aimed to assess and monitor the incidence and recovery of cognitive and psychological changes associated with the abuse of petrol and alcohol among Indigenous Australians. Study participants included 224 Indigenous Australians recruited from educational or rehabilitation facilities in the Northern Territory, who were classified as petrol or alcohol abusers or healthy controls on the basis of detailed substance use histories. Baseline cognitive and psychological assessments were completed on admission to rehabilitation, and then fortnightly for the duration of treatment. Community follow up assessments were also conducted approximately one year after treatment. The cultural and psychometric validity of the selected assessments were first established by evaluating test-retest reliability, practice effects, and any demographic factors that impact on test performance for this group. Impairments were then identified for each of the petrol and alcohol groups across the study timeframe using cross sectional and longitudinal comparisons with matched control groups. At baseline, petrol sniffers aged 11-25 years with an average of five years chronic use demonstrated impairments on tasks of visual motor, attention, memory, learning and executive functions. Importantly, the majority of these impairments normalised within two months of abstinence by the end of treatment, however speed deficits on visual motor, memory and executive function tasks persisted after 12 months. Similarly, impairments in visual motor, attention, memory, learning and executive functions were observed among both chronic and episodic alcohol users aged 18-60 years with an average of 16 years use. Most resolved within four weeks of abstinence, although visual motor deficits recovered within 11 months. The impairment and recovery profiles of both chronic and episodic users were similar, suggesting that episodic alcohol use may be as damaging as chronic use. Cognitive deficits, psychological symptoms and continued petrol and alcohol availability were key factors that led to their continued abuse following treatment discharge.
Cleanup of trimethylamine (fishy odor) from contaminated air by various species of Sansevieria spp. and their leaf materials
Creators: name: Phattara Boraphech
name: Parinda Suksabye
name: Nipaporn Kulinfra
name: Wascharangkoon Kongsang
name: Paitip Thiravetyan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: 60506 Virology

description: Removal of trimethylamine (TMA) by 10 different living Sansevieria spp. and their dried leaf materials was studied. The results showed that living Sansevieria kirkii was the most effective plant while Sansevieria masoniana was the least effective in TMA removal. Two major pathways were involved in stomata opening and epicuticular wax on the leaf surface. In the presence of TMA, the stomata opening in Sansevieria spp. was induced, which enhanced TMA removal under light conditions. Dried leaf powders of Sansevieria spp. adsorbed TMA through their waxes. Therefore, both living and non-living Sansevieria spp. can be effectively used for removal of TMA.
Céramique
Epinetron
Epinetron attique Bellorophon combattant Chimère
Creators: name: SAM
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2016

description: date: 425-420
Cleanup of Trimethylamine (fishy odor) from contaminated air by various species of Sansevieria spp. and their leaf materials
Creators: name: Phattara Boraphech
name: Parinda Suksabye
name: Nipaporn Kulinfra
name: Wascharangkoon Kongsang
name: Paitip Thiravetyan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: 60506 Virology

description: Removal of trimethylamine (TMA) by 10 different living Sansevieria spp. and their dried leaf materials was studied. The results showed that living S. kirkii was the most effective plant while S. masoniana was the least effective in TMA removal. Two major pathways were involved in stomata opening and epicuticular wax on the leaf surface. In the presence of TMA, the stomata opening in Sansevieria spp. was induced and enhanced TMA removal under light conditions. Dried leaf powders of Sansevieria spp. adsorbed TMA through their waxes. Therefore, both living and non-living Sansevieria spp. can be effectively used in removal of TMA.
Epigenetic zonation and fluid flow history of uranium-bearing fluvial aquifer systems, South Texas uranium province
Creators: name: University Of Texas At Austin. Bureau Of Economic Geology
Publisher: name: University of Texas at Austin. Bureau of Economic Geology
Year: 1982
Subjects: Geology -- Texas
Uranium mines and mining -- Texas
Uranium ores -- Texas

description: Tx Doc no.: Z, UA220.7, R299, no. 119.