cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MOESM2 of A high-resolution genomic composition-based method with the ability to distinguish similar bacterial organisms
Creators: name: Zhou, Yizhuang
name: Zhang, Wenting
name: Wu, Huixian
name: Huang, Kai
name: Jin, Junfei
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Developmental Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Figure S1. Determination of the optimal species-level cutoffs for the four published methods based on F-score. Figure S2. F-scores for 10 samplings for each method. Figure S3. Determination of the species-level cutoffs for the four published methods based on Rand index. Figure S4. Rand indexes for 10 samplings for each method. Figure S5. Instraspecific Pearson correlation coefficient distribution for each method. Figure S6. Normalization of tetranucleotide-derived z-values. Figure S7. Histrogram showing the TZMD distributions for both intraspecific and interspecific pairs. Figure S8. Comparison base on Rand index showed TZMD slightly improved species differentiation. Figure S9. TETRA cannot differentiate Brucella species belonging to one single genospecies. Figure S10. TETRA cannot differentiate Y. pseudotuberculosis and Y. pestis belonging to one single genospecies. Figure S11. TZMD differentiates Y. pestis and Y. pseudotuberculosis belonging to one single genospecies. Figure S12. TETRA cannot differentiate B. mallei and B. pseudomalleiÂ belonging to one single genospecies. Figure S13. TZMD differentiates B. mallei and B. pesudomalleiÂ belonging to one single genospecies. Figure S14. TETRA cannot differentiates sub species and intraspecific strains of Campylobacter jejuni. Figure S15. TZMD differentiates all subspecies of Franscisella tularensis. Figure S16. TETRA cannot differentiate two subspecies of Francisella tularensis. Figure S17. TZMD distinguishes intraspecific strains of Streptococcus pyogenes. Figure S18. TETRA cannot differentiate intraspecific strains of Streptococcus pyogenes. Figure S19. TZMD distinguishes intraspecific strains of Bacillus cereus. Figure S20. TETRA cannot differentiate intraspecific strains of Bacillus cereus. Figure S21. Impact of genomic completeness on TZMD and TETRA for species differentiation. Figure S22. Binning performance of TZMD and TETRA. Table S1. TZMD and TETRA values for differently-sized genomes.
[SADE] A Maple package for the Symmetry Analysis of Differential Equations
Creators: name: Filho, Tarcí sio M. Rocha
name: Figueiredo, Annibal
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We present the package SADE (Symmetry Analysis of Differential Equations) for the determination of symmetries and related properties of systems of differential equations. The main methods implemented are: Lie, nonclassical, Lie-Bäcklund and potential symmetries, invariant solutions, first-integrals, Nöther theorem for both discrete and continuous systems, solution of ordinary differential equations, reduction of order or dimension using Lie symmetries, classification of differential equations, Casimir invariants, and the quasi-polynomial formalism for ODE's (previously implemented in the package QPSI by the authors) for the determination of quasi-polynomial first-integrals, Lie symmetries and invariant surfaces. Examples of use of the package are given.
The 1.6 micron near infrared nuclei of 3C radio galaxies: Jets, thermal emission or scattered light?
Creators: name: Baldi, R. D.
name: Chiaberge, M.
name: Capetti, A.
name: Sparks, W.
name: Macchetto, F. D.
name: O'Dea, C. P.
name: Axon, D. J.
name: Baum, S. A.
name: Quillen, A. C.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Using HST NICMOS 2 observations we have measured 1.6-micron near infrared nuclear luminosities of 100 3CR radio galaxies with z<0.3, by modeling and subtracting the extended emission from the host galaxy. We performed a multi-wavelength statistical analysis (including optical and radio data) of the properties of the nuclei following classification of the objects into FRI and FRII, and LIG (low-ionization galaxies), HIG (high-ionization galaxies) and BLO (broad-lined objects) using the radio morphology and optical spectra, respectively. The correlations among near infrared, optical, and radio nuclear luminosity support the idea that the near infrared nuclear emission of FRIs has a non-thermal origin. Despite the difference in radio morphology, the multi-wavelength properties of FRII LIG nuclei are statistically indistinguishable from those of FRIs, an indication of a common structure of the central engine. All BLOs show an unresolved near infrared nucleus and a large near infrared excess with respect to FRII LIGs and FRIs of equal radio core luminosity. This requires the presence of an additional (and dominant) component other than the non-thermal light. Considering the shape of their spectral energy distribution, we ascribe the origin of their near infrared light to hot circumnuclear dust. A near infrared excess is also found in HIGs, but their nuclei are substantially fainter than those of BLO. This result indicates that substantial obscuration along the line-of-sight to the nuclei is still present at 1.6 micron. Nonetheless, HIGs nuclei cannot simply be explained in terms of dust obscuration: a significant contribution from light reflected in a circumnuclear scattering region is needed to account for their multiwavelength properties.
description: 20 pages, 16 figures. Accepted for publication on ApJ
Additional file 6 of Role of antiangiogenic agents in first-line treatment for advanced NSCLC in the era of immunotherapy
Creators: name: Pang, Lan-Lan
name: Gan, Jia-Di
name: Huang, Yi-Hua
name: Liao, Jun
name: Zhuang, Wei-Tao
name: Ali, Wael-Abdullah-Sultan
name: Hong, Shao-Dong
name: Zhang, Li
name: Fang, Wen-Feng
Publisher: name: figshare
Year: 2023
Subjects: Pharmacology
Biotechnology
Cancer
Science Policy

description: Additional file 6: Supplementary Figure 3. Bayesian ranking profile based on the SUCRA results of disease-controlled rate (DCR), decrement rate of any grade toxicity assessment, and rate of side effects leading to discontinuation and death.
Supplemental Material.docx
Creators: name: Pan, Xiong-Fei
name: Chen, Zsu-Zsu
name: Wang, Thomas J.
name: Shu, Xiang
name: Cai, Hui
name: Cai, Qiuyin
name: Clish, Clary B.
name: Shi, Xu
name: Zheng, Wei
name: Gerszten, Robert E.
name: Shu, Xiao-Ou
name: Yu, Danxia
Publisher: name: figshare
Year: 2021
Subjects: subject: 111706 Epidemiology
subject: FOS: Health sciences

description: This is the Supplementary Material for the manuscript, Plasma Metabolomic Signatures of Obesity and Risk of Type 2 Diabetes.
Inverse problems of symbolic dynamics
Creators: name: Belov, A. Ya.
name: Kondakov, G. V.
name: Mitrofanov, I.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: This paper reviews some results regarding symbolic dynamics, correspondence between languages of dynamical systems and combinatorics. Sturmian sequences provide a pattern for investigation of one-dimensional systems, in particular interval exchange transformation. Rauzy graphs language can express many important combinatorial and some dynamical properties. In this case combinatorial properties are considered as being generated by substitutional system, and dynamical properties are considered as criteria of superword being generated by interval exchange transformation. As a consequence, one can get a morphic word appearing in interval exchange transformation such that frequencies of letters are algebraic numbers of an arbitrary degree. Concerning multydimensional systems, our main result is the following. Let P(n) be a polynomial, having an irrational coefficient of the highest degree. A word $w$ $(w=(w_n), n\in \nit)$ consists of a sequence of first binary numbers of $\{P(n)\}$ i.e. $w_n=[2\{P(n)\}]$. Denote the number of different subwords of $w$ of length $k$ by $T(k)$ . \medskip {\bf Theorem.} {\it There exists a polynomial $Q(k)$, depending only on the power of the polynomial $P$, such that $T(k)=Q(k)$ for sufficiently great $k$.}
Boosting hierarchical structure formation with scalar-interacting dark matter
Creators: name: Hellwing, Wojciech A.
name: Knollmann, Steffen R.
name: Knebe, Alexander
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the effect of long-range scalar interactions in dark matter (DM) models of cosmic structure formation with a particular focus on the formation times of haloes. Utilising $N$-body simulations with $512^3$ DM particles we show that in our models dark matter haloes form substantially earlier: tracing objects up to redshift $z\sim6$ we find that the formation time, as characterised by the redshift $z_{1/2}$ at which the halo has assembled half of its final mass, is gradually shifted from $z_{1/2}\approx 1.83$ in the fiducial LCDM model to $z_{1/2}\approx 2.54$ in the most extreme self-interaction model. This is accompanied by a shift of the redshift that marks the transition between merger and steady accretion epochs from $z_{*}\approx 4.32$ in the \lcdm\ halos to $z_{*}\approx 6.39$ in our strongest interaction model. In other words, the scalar-interacting model employed in this work produces more structures at high redshifts, prolonging at the same time the steady accretion phases. These effects taken together can help the LCDM model to account for a high redshift reionisation as indicated by the WMAP data and can alleviate issues related to the survival of the thin-disk dominated galaxies at low redshifts.
description: 5 pages, 3 figures, 1 table. Final version to be printed in MNRAS Letters. 4 new references added
Second Order Phase Transition in Anisotropic Lattice Gauge Theories with Extra Dimensions
Creators: name: Nicolis, Stam
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Field theories with extra dimensions live in a limbo. While their classical solutions have been the subject of considerable study, their quantum aspects are difficult to control. A special class of such theories are anisotropic gauge theories. The anisotropy was originally introduced to localize chiral fermions. Their continuum limit is of practical interest and it will be shown that the anisotropy of the gauge couplings plays a crucial role in opening the phase diagram of the theory to a new phase, that is separated from the others by a second order phase transition. The mechanism behind this is generic for a certain class of models, that can be studied with lattice techniques. This leads to new perspectives for the study of quantum effects of extra dimensions.
description: 7 pages, 1 figure. Uses PoS.cls. Contribution to The XXVIII International Symposium on Lattice Filed Theory, June 14-19,2010,Villasimius, Sardinia Italy
Universal coding for transmission of private information
Creators: name: Datta, Nilanjana
name: Hsieh, Min-Hsiu
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We consider the scenario in which Alice transmits private classical messages to Bob via a classical-quantum channel, part of whose output is intercepted by an eavesdropper, Eve. We prove the existence of a universal coding scheme under which Alice's messages can be inferred correctly by Bob, and yet Eve learns nothing about them. The code is universal in the sense that it does not depend on specific knowledge of the channel. Prior knowledge of the probability distribution on the input alphabet of the channel, and bounds on the corresponding Holevo quantities of the output ensembles at Bob's and Eve's end suffice.
description: 31 pages, no figures. Published version
Mariátegui ́s Peru: Detainees in the time and the awakening of an era
Creators: name: Canaza-Choque, Franklin Américo
Publisher: name: figshare
Year: 2021
Subjects: subject: Sociology
subject: FOS: Sociology

description: En el supremo intento de desvelar en el Perú aquellos motores de impulso que permitieron al underground poner en marcha y dinámica evolución de los primeros años de la historia republicana del siglo XX. El interés se fundamenta en argumentar, en torno a otras, algunas aristas del impacto que significó para los lectores del titular de los 7 ensayos el comportamiento de una etapa histórica de forma más ceñida a finales del siglo XIX y principios del XX, como dos periodos de ruptura y el síndrome de parálisis socioemocional dejado por la Guerra del Pacífico (1879-1883); pero al mismo tiempo, de movimiento civilizatorio de desafío, resistencia y construcción nunca antes visto y articulado colectivamente por los efectos sobrevenidos de la penetración de las primeras e incipientes energías capitalizadoras en el territorio peruano y de las cuales fue pieza clave de ese indómito resistencia,
Non-existence of metrics with positive scalar curvature on the n-torus
Creators: name: Friedman, Benjamin
Publisher: name: University of British Columbia
Year: 2022

description: In this thesis, we explore a famous theorem of Schoen and Yau stating that there exists no metric of positive scalar curvature on the n-torus Tⁿ, for n ≤ 7. The proof is by induction: One first assumes a metric of positive scalar curvature on Tⁿ. Then, by applying techniques from geometric measure theory, the direct method of the calculus of variations yields an area minimizing hypersurface in each non-trivial homology class χ ∈ Hn-1(Tⁿ; ℤ). Using a stability argument, it is then shown that the induced metric on this hypersurface is conformal to a metric of positive scalar curvature, contradicting the inductive assumption.
Additional file 1 of Novel fusion protein PK5-RL-Gal-3C inhibits hepatocellular carcinoma via anti-angiogenesis and cytotoxicity
Creators: name: Gao, Xiaoge
name: Jiang, Pin
name: Wei, Xiaohuan
name: Zhang, Wei
name: Zheng, Jiwei
name: Sun, Shishuo
name: Yao, Hong
name: Liu, Xiangye
name: Zhang, Qing
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1.
Contribution of low-lying vector resonances to polarization observables in \bar B_d^0 -> \bar K*0 e+ e- decay
Creators: name: Korchin, Alexander Yu.
name: Kovalchuk, Vladimir A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The branching ratio and other observables for the rare flavour-changing neutral current decay \bar B_d^0 -> \bar K*0 (-> K- pi+) e+ e- are studied below the \bar{c} c threshold. The total amplitude for this decay includes the term coming from the standard model effective Hamiltonian and the term generated by the processes \bar B_d^0 -> \bar K*0 (-> K- pi+) V with intermediate low-lying vector resonances V = rho(770), omega(782), phi(1020) decaying into the e+ e- pair. The resonance contribution to the branching ratio, polarization fractions of the K* meson and coefficients in the angular distribution is calculated. The influence of the resonances on the integrated observables in the region of electron-positron invariant mass up to 1 GeV is studied in view of the planned measurements of the photon polarization at the LHCb.
description: 14 pages, 6 figures, revtex4; two figures omitted, a few references added; version accepted for publication in Physical Review D
Development and evaluation of a multi-epitope subunit vaccine against group B Streptococcus infection
Creators: name: Zhang, Yumin
name: Liang, Song
name: Zhang, Shiyu
name: Zhang, Shidan
name: Yu, Yong
name: Yao, Huochun
name: Liu, Yongjie
name: Zhang, Wei
name: Liu, Guangjin
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Streptococcus agalactiae (Group B Streptococcus, GBS) is a multi-host pathogen, even causing life-threatening infections in newborns. Vaccination with GBS crossed serotypes vaccine is one of the best options for long-term infection control. Here we built a comprehensive in silico epitope-prediction workflow pipeline to design a multivalent multiepitope-based subunit vaccine containing 11 epitopes against Streptococcus agalactiae (MVSA). All epitopes in MVSA came from the proteins which were antigenic-confirmed, virulent-associated, surface-exposed and conserved in ten GBS serotypes. The in-silico analysis showed MVSA had potential to evoke strong immune responses and enable worldwide population coverage. To validate MVSA protection efficacy against GBS infection, immune protection experiments were performed in a mouse model. Importantly, MVSA induced a high titre of antibodies, significant proliferation of mice splenocytes and elicited strong protection against lethal-dose challenge with a survival rate of 100% in mice after three vaccinations. Meanwhile, the polyclonal antibody against MVSA did not only inhibit for growth of GBS from six crucial serotypes in vitro, but also protect 100% naive mice from GBS lethal challenge. These active and passive immunity assay results suggested that MVSA could therefore be an efficacious multi-epitope vaccine against GBS infection.
Mapa conceptual Auditoría de un Sistema de Gestión
Creators: name: Remolina Pineda, Maryuri Paola
name: Pérez Fernández, Blanca Johanna
Publisher: name: Zenodo
Year: 2023
Subjects: Auditoría
Sistema de Gestión
Evidencia
Principios
Tipos de auditoría

description: Mapa conceptual en el cual se sintetiza la información relacionada con auditoría en un sistema de gestión, tales como definición de auditoría, tipos de auditoría, programa de auditoría, alcance de la auditoría, plan de auditoría, criterios de auditoría, evidencia de auditoría, evidencia objetiva, hallazgos, conclusiones y principios de la auditoría.
description: {"references": ["Instituto Colombiano de Normas T\u00e9cnicas y Certificaci\u00f3n (2018). GTC-ISO 19011: Directrices de auditor\u00eda en un sistema de gesti\u00f3n."]}
Eternal Inflation with Liouville Cosmology
Creators: name: Nakayama, Yu
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a concrete holographic realization of the eternal inflation and its census taker in (1+1) dimensional Liouville gravity by applying the FRW/CFT philosophy proposed by Freivogel, Sekino, Susskind and Yeh (FSSY). The dual boundary theory is nothing but the old matrix model describing the two-dimensional Liouville gravity coupled with minimal model matter fields. In Liouville gravity, the flat Minkowski space or even the AdS space will decay into the dS space, which is in stark contrast with higher dimensional theories, but the spirit of the FSSY conjecture applies with only minimal modification. We investigate the classical geometry as well as some correlation functions to support our claim. We also study an analytic continuation to the time-like Liouville theory to discuss possible applications in (1+3) dimensional cosmology along with the original FSSY conjecture, where the boundary theory involves the time-like Liouville theory. We show that the decay rate in the (1+3) dimension is more suppressed due to the quantum gravity correction of the boundary theory.
description: 32 pages, v2: published version, many improvement
Binary Neutron Star Remnants: the most extreme matter in the Universe
Creators: name: EASTER, PAUL JOHN
Publisher: name: Monash University
Year: 2021
Subjects: subject: 20105 General Relativity and Gravitational Waves
subject: FOS: Physical sciences
subject: Astrophysics

description: Binary neutron star post-merger remnants consist of the most extreme matter in the Universe, being extremely dense and hot. We expect to be able to measure gravitational waves from these remnants in the near future. However, we need waveforms of the gravitational waves to be able to detect remnants. Simulations can generate these waveforms, but they are much too slow for use in detections. We develop methods to produce these waveforms significantly faster and use these methods to measure how far away a remnant needs to be to estimate when it will collapse into a black hole.
Bäcklund Transformations for the Kirchhoff Top
Creators: name: Ragnisco, Orlando
name: Zullo, Federico
Publisher: name: arXiv
Year: 2010
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We construct Bäcklund transformations (BTs) for the Kirchhoff top by taking advantage of the common algebraic Poisson structure between this system and the $sl(2)$ trigonometric Gaudin model. Our BTs are integrable maps providing an exact time-discretization of the system, inasmuch as they preserve both its Poisson structure and its invariants. Moreover, in some special cases we are able to show that these maps can be explicitly integrated in terms of the initial conditions and of the "iteration time" $n$. Encouraged by these partial results we make the conjecture that the maps are interpolated by a specific one-parameter family of hamiltonian flows, and present the corresponding solution. We enclose a few pictures where the orbits of the continuous and of the discrete flow are depicted.
Additional file 3 of Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis
Creators: name: Yuan, Xiwei
name: Li, Lu
name: Zhang, Ying
name: Ai, Rong
name: Li, Dongdong
name: Dou, Yao
name: Hou, Mengmeng
name: Zhao, Dandan
name: Zhao, Suxian
name: Nan, Yuemin
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: Supplementary Material 3
Collective many-body interaction in Rydberg dressed atoms
Creators: name: Honer, Jens
name: Weimer, Hendrik
name: Pfau, Tilman
name: Büchler, Hans Peter
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a method to control the shape and character of the interaction potential between cold atomic gases by weakly dressing the atomic ground state with a Rydberg level. For increasing particle densities, a crossover takes place from a two-particle interaction into a collective many-body interaction, where the dipole-dipole/van der Waals Blockade phenomenon between the Rydberg levels plays a dominant role. We study the influence of these collective interaction potential on a Bose-Einstein condensate, and present the optimal parameters for its experimental detection.
description: 4 pages, 3 figures Accepted for publication as a Letter in Physical Review Letters
The Great Stampede. Humans walking in liquid modernity
Creators: name: Canaza-Choque, Franklin Américo
Publisher: name: figshare
Year: 2021
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Environmental Humanities
subject: 180111 Environmental and Natural Resources Law
subject: FOS: Law

description: Más allá de los manantiales que pueden llevar a una movilización insistente de los humanos, incuban otras razones poderosamente caóticas que enfrentan los migrantes. Bajo esta premisa, el objetivo es analizar la evolución del fenómeno migratorio en un contexto de tragedia humanitaria y desgarro planetario. La localización de este análisis de fue dos posibles razones por las que se externaliza un moderno noma-dism de gama alta. Ambos, lógicamente letales en su tratamiento. El primero, destaca que la migración humana es una respuesta mecánica al cambio climático. El segundo, es el resultado de la mutilación implacable del bienestar que invoca la guerra y la violencia generalizada en todas sus formas. Dos caminos que sin duda, por su globalización e inflexión, han transformado intensamente las políticas extraterritoriales y el movimiento humano en tiempos de desesperación global.
Zur Erinnerung an Johannes Gassmann-Peter, Sekundarlehrer, geboren den 10. März 1859, gestorben den 26. März 1910
Creators: name: (:Unkn) Unknown
Publisher: name: Buchdruckerei G. Krebs Fischmarkt 1
Year: 1910
Subjects: subject: 920 Biografien, Genealogie, Insignien
subject: Nachruf
subject: Gassmann, Johannes
subject: Küsnacht (Kanton Zürich)

description: Enthält: Ansprache von Pfarrer E. Stähelin bei der Beerdigung, 28. März 1910; Rede von Rektor Zürrer bei der Beerdigung.
title: ÐÐ¸Ð·Ð½ÐµÑ-ÑÐµÐ½ÑÑÐ° Ñ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¾Ð¹ 5D ÑÐ¼ÐµÑÑ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Business center with the development of 5D estimates
Creators: name: Ð¡ÑÐ¾Ð»ÑÐ½Ð¸ÐºÐ¾Ð²Ð°, ÐÑÐ¸ÑÑÐ¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: 5D ÑÐ¼ÐµÑÐ°
ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ð¸
bim wizard
smeta wizard
bim Ð¼Ð¾Ð´ÐµÐ»Ñ
Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¹ ÑÐ°ÑÑÑÑ
ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ñ
Ð½Ð¾Ð²Ð¾Ð²Ð²ÐµÐ´ÐµÐ½Ð¸Ðµ
5D estimates
technologies
bim model
automated calculation
economic indicator
new-management

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ð° ÑÑÑÑ ÑÐ°Ð±Ð¾ÑÑ 5D ÑÐ¼ÐµÑÐ°, Ð¿Ð¾ÐºÐ°Ð·Ð°Ð½Ñ Ð¿ÑÐµÐ¸Ð¼ÑÑÐµÑÑÐ²Ð° Ð¸Ð½-ÑÑÑÑÐ¼ÐµÐ½ÑÐ°. ÐÑÐ¾ÐµÐºÑÐ¸ÑÑÐµÐ¼ÑÐ¹ Ð±Ð¸Ð·Ð½ÐµÑ-ÑÐµÐ½ÑÑ Ð±ÑÐ» Ð¿ÑÐ¾ÑÐ°Ð±Ð¾ÑÐ°Ð½ Ð² 3-Ñ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½ÑÑ ÐºÐ¾Ð¼-Ð¿Ð»ÐµÐºÑÐ°Ñ: Â«Autodesk Revit 2017Â», Â«BIM WIZARDÂ» Ð¸ Â«SmetaWIZARDÂ». ÐÐ·ÑÑÐµÐ½Ð¾ Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð¸Ðµ ÑÐµÑÑÑÑÐ¾Ð² Ð¸Ð· Ð±Ð°Ð·Ñ Ð´Ð°Ð½Ð½ÑÑ Ð´Ð»Ñ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð² BIM Ð¼Ð¾Ð´ÐµÐ»Ð¸. Ð¡Ð¾Ð·Ð´Ð°Ð½Ð° ÑÑÑÑÐºÑÑÑÐ° ÑÐ¼ÐµÑÑ Ð² Â«BIM WIZARDÂ». Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ ÑÐ°ÑÑÑÐ¸ÑÐ°Ð½Ð° Ð»Ð¾ÐºÐ°Ð»ÑÐ½Ð°Ñ ÑÐ¼ÐµÑÐ° Ð½Ð° Ð½Ð°Ð´Ð·ÐµÐ¼Ð½ÑÑ ÑÐ°ÑÑÑ Ð¸ Ð¿Ð¾Ð»ÑÑÐµÐ½Ñ ÑÐµÑÐ½Ð¸ÐºÐ¾-ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸ Ð·Ð´Ð°Ð½Ð¸Ñ.
description: This paper outlines the essence of the work of 5D estimates, shows the advantages of the tool. The designed business center was developed in 3 software complexes: âAuto-desk Revit 2017â, âBIM WIZARDâ and âSmetaWIZARDâ. The assignment of resources from the database to the BIM model elements has been studied. The cost structure was cre-ated at BIM WIZARD, and as a result, a local estimate for the above-ground part was cal-culated and the technical and economic indicators of the building were obtained.
Action-gradient-minimizing pseudo-orbits and almost-invariant tori
Creators: name: Dewar, R. L.
name: Hudson, S. R.
name: Gibson, A. M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: Fluid Dynamics (physics.flu-dyn)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Transport in near-integrable, but partially chaotic, $1 1/2$ degree-of-freedom Hamiltonian systems is blocked by invariant tori and is reduced at \emph{almost}-invariant tori, both associated with the invariant tori of a neighboring integrable system. "Almost invariant" tori with rational rotation number can be defined using continuous families of periodic \emph{pseudo-orbits} to foliate the surfaces, while irrational-rotation-number tori can be defined by nesting with sequences of such rational tori. Three definitions of "pseudo-orbit," \emph{action-gradient--minimizing} (AGMin), \emph{quadratic-flux-minimizing} (QFMin) and \emph{ghost} orbits, based on variants of Hamilton's Principle, use different strategies to extremize the action as closely as possible. Equivalent Lagrangian (configuration-space action) and Hamiltonian (phase-space action) formulations, and a new approach to visualizing action-minimizing and minimax orbits based on AGMin pseudo-orbits, are presented.
description: Accepted for publication in a special issue of Communications in Nonlinear Science and Numerical Simulation (CNSNS) entitled "The mathematical structure of fluids and plasmas : a volume dedicated to the 60th birthday of Phil Morrison"
Additional file 2 of Role of antiangiogenic agents in first-line treatment for advanced NSCLC in the era of immunotherapy
Creators: name: Pang, Lan-Lan
name: Gan, Jia-Di
name: Huang, Yi-Hua
name: Liao, Jun
name: Zhuang, Wei-Tao
name: Ali, Wael-Abdullah-Sultan
name: Hong, Shao-Dong
name: Zhang, Li
name: Fang, Wen-Feng
Publisher: name: figshare
Year: 2023
Subjects: Pharmacology
Biotechnology
Cancer
Science Policy

description: Additional file 2.
On the Derivatives of Central Loops
Creators: name: Jaiyeola, Temitope
name: Adeniran, John
Publisher: name: figshare
Year: 2021
Subjects: Algebra

description: The right (left) derivative, −isotopes of a C-loop are shown to be C-loops. Furthermore, for a central loop (L, F), it is shown that a family are systems of isotopic C-loops that obey a form of generalised
distributive law. It is proved that for a loop (L, θ) to be an LC(RC,C)-loop, it is necessary and sufficient for the parastrophe (L, θ∗) to be a RC(LC,C)-loop.
Hence, isotopes (L,⊗) and (L,+) of (L, θ) and (L, θ∗) respectively are proved to be isotopic if either (L,⊗) or (L,+) is commutative. It is shown that C-loops are
isotopic to some finite indecomposable groups of the classes Di, i = 1, 2, 3, 4, 5
and that the center of such C-loops have a rank of 1, 2 or 3.
Time-delayed-feedback control of pattern formation in symmetrical bistable media
Creators: name: He, Ya-feng
name: Bao-Quan
name: Hu, Bambi
Publisher: name: arXiv
Year: 2010
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Effects of time-delayed-feedback on pattern formation are studied in symmetrical bistable media. The results show that the time delay alters the behavior of the front bifurcation remarkably. The critical point of the Nonequilibrium Ising-Bloch bifurcation is shifted, which results from the competition between the feedbacks of the two variables. The stability of the front to transverse perturbation is also changed by the time delay, leading to a transition between spiral and labyrinthine patterns. One can control the pattern formation in bistable media by using time-delayed-feedback.
description: 8 figures
On the Derivatives of Central Loops
Creators: name: Jaiyeola, Temitope
Publisher: name: figshare
Year: 2021
Subjects: Algebra

description: The right (left) derivative, −isotopes of a C-loop are shown to be C-loops. Furthermore, for a central loop (L, F), it is shown that a family are systems of isotopic C-loops that obey a form of generalised
distributive law. It is proved that for a loop (L, θ) to be an LC(RC,C)-loop, it is necessary and sufficient for the parastrophe (L, θ∗) to be a RC(LC,C)-loop.
Hence, isotopes (L,⊗) and (L,+) of (L, θ) and (L, θ∗) respectively are proved to be isotopic if either (L,⊗) or (L,+) is commutative. It is shown that C-loops are
isotopic to some finite indecomposable groups of the classes Di, i = 1, 2, 3, 4, 5
and that the center of such C-loops have a rank of 1, 2 or 3.
INTERACCIÓN ENTRE EL SER HUMANO Y EL COCODRILO AMERICANO (Crocodylus acutus) EN EL GRAN HUMEDAL TEMPISQUE, GUANACASTE, COSTA RICA.
Creators: name: Carrillo Rivera Natalia
Publisher: name: Zenodo
Year: 2019
Subjects: Crocodylus acutus, conflicto humano-vida silvestre, percepción, interacción humano-cocodrilo

description: Debido al desarrollo y expansión urbana la interacción entre el hombre y la vida silvestre se ha incrementado, y si bien estas interacciones pueden tener beneficios para ambas partes, también existen aquellas que conducen a conflictos. En el Gran Humedal Tempisque el hábitat del cocodrilo (Crocodylus acutus) ha estado sometido a mucha presión, lo que ha reducido considerablemente el espacio disponbible para la especie, esto junto al hecho de que la población de cocodrilos se ha cuadriplicado en los ultimos 15 años, ha llevado a que la probabilidad de encuentro entre los cocodrilos y las personas aumente. Se evaluó la interacción entre el ser humano y el cocodrilo desde de una aproximación cualitativa de la investigación social y se utilizó la técnica de la entrevista enfocada semiestructurada para conocer las percepciones de los diferentes actores sociales y establecer el nivel de tolerancia en la comunidades aledañas al Río Tempisque. Se identificó la existencia de conflicto con algunos sectores de la población por la presencia de los cocodrilos en 22 poblados cercanos al Gran Humedal Tempisque, la percepción negativa de las personas de las comunidades aledañas al río acerca de los cocodrilos es mayor a la positiva y está influenciada por el género y el poblado de residencia. La percepción negativa es mayor en las mujeres y en los poblados Guardia, Comunidad, Palmira, Hacienda El Pelón de la Bajura, Filadelfia, La Guinea, Corralillo, Rosario, Puerto Humo, Pozo de Agua, San Lázaro, Caballito, Puerto Moreno y Bebedero. Además, se pudo determinar que el reconocimiento o no de beneficios o afectaciones dadas por la presencia de cocodrilos tiene un efecto en la percepción de las personas. Por otra parte, se encontró que los investigadores y funcionarios del SINAC poseen interés en colaborar para mejorar las condiciones y disminuir el conflicto y las empresas tienen interés en trabajar en conjunto con las autoridades para solucionar los problemas que trae la presencia de cocodrilos en sus instalaciones.
description: Tesis de Maestría financiada por el Programa de apoyo de investigación para estudiante del Grupo de Especialistas de Cocodrilos de UICN-SSC (CSG PAIE)
Higher dimensional thin-shell wormholes in Einstein-Yang-Mills-Gauss-Bonnet gravity
Creators: name: Mazharimousavi, S. Habib
name: Halilsoy, M.
name: Amirabi, Z.
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We present thin-shell wormhole solutions in Einstein-Yang-Mills-Gauss-Bonnet (EYMGB) theory in higher dimensions d\geq5. Exact black hole solutions are employed for this purpose where the radius of thin-shell lies outside the event horizon. For some reasons the cases d=5 and d>5 are treated separately. The surface energy-momentum of the thin-shell creates surface pressures to resist against collapse and rendering stable wormholes possible. We test the stability of the wormholes against spherical perturbations through a linear energy-pressure relation and plot stability regions. Apart from this restricted stability we investigate the possibility of normal (i.e. non-exotic) matter which satisfies the energy conditions. For negative values of the Gauss-Bonnet (GB) parameter we obtain such physical wormholes.
description: 9 pages, 6 figures. Dedicated to the memory of Rev. Ibrahim Eken (1927-2010) of Turkey
Length-minimizing closed curves on manifolds with boundary
Creators: name: Kohut, Hannah
Publisher: name: University of British Columbia
Year: 2022

description: The purpose of this thesis is to explore the properties of closed curves which are length-minimizing in a nontrivial homotopy class of a compact Riemannian manifold with boundary. This project was inspired by a question asked by Professor Liam Watson about the existence of length-minimizing curves on a torus with finitely many disks removed, and whether these curves leave the boundary components tangentially. In our research, we extend the question to compact smooth Riemannian manifolds with smooth boundary. We first discuss some preliminary results to determine an appropriate class of curves to minimize over. We then explore the properties of the length and energy functionals, showing that a minimizer of the energy is also a minimizer of the length. We directly minimize the energy functional to show the existence of a length-minimizing curve in any nontrivial homotopy class of a compact Riemannian manifold with boundary. Finally, we address the regularity of length-minimizing curves, showing that they are piecewise geodesics (possibly with infinitely many pieces).
Carbonized rice husk coated solar absorber for clean water generation from seawater with a solar still
Creators: name: Karen, Wong Min Jin
name: Wong, C.Y.
name: Wang, Zhipeng
name: Liew, Willey Y.H.
name: Melvin, G.J.H.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Space Science
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: This study demonstrated the generation of clean water from seawater collected at the beach coast in Universiti Malaysia Sabah, Malaysia, with carbonized rice husk coated melamine sponge as solar absorber by a solar still. Melamine sponge was utilized as seawater transportation medium since its porous structure is excellent in channeling the seawater. Whereas carbonized rice husk was used as the photothermal conversion material for its efficient heat absorption due to its black color and porous structure. Implementing air gap between the seawater body and solar absorber, and restricted water pathway assisted in localizing heat on the top surface of solar absorber. Clean water was generated under direct solar radiation during the day at an open space with average solar intensity around 1.1 ∼ 1.2 kW/m2 (slightly higher than 1 sun) for about four hours. Efficiency of the solar absorber was calculated, while the quality of the generated clean water was observed in terms of salinity and pH value. Insulated solar still with carbon-coated sponge showed the highest efficiency at about 54.74%. Salinity of the collected clean water significantly reduced to consumable level which was approximately 55 ppm, and the pH value at about 6.63 where it was within the safe limit of the drinkable water pH.
Fostering biodiversity presentation poster.pdf
Creators: name: Ussenaliyeva, Aizhan
Publisher: name: figshare
Year: 2022
Subjects: subject: 40301 Basin Analysis
subject: FOS: Earth and related environmental sciences
subject: 40501 Biological Oceanography
subject: Atmospheric Sciences

description: This poster is visualising the concept of my presentation related to the Save Lake Balkhash International Project.
The first bent double lobe radio source in a known cluster filament: Constraints on the intra-filament medium
Creators: name: Edwards, Louise O. V.
name: Fadda, Dario
name: Frayer, David T.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We announce the first discovery of a bent double lobe radio source (DLRS) in a known cluster filament. The bent DLRS is found at a distance of 3.4 Mpc from the center of the rich galaxy cluster, Abell~1763. We derive a bend angle alpha=25deg, and infer that the source is most likely seen at a viewing angle of Phi=10deg. From measuring the flux in the jet between the core and further lobe and assuming a spectral index of 1, we calculate the minimum pressure in the jet, (8.0+-3.2)x10^-13 dyn/cm^2, and derive constraints on the intra-filament medium (IFM) assuming the bend of the jet is due to ram pressure. We constrain the IFM to be between (1-20)x10^-29 gm/cm^3. This is consistent with recent direct probes of the IFM and theoretical models. These observations justify future searches for bent double lobe radio sources located several Mpc from cluster cores, as they may be good markers of super cluster filaments.
description: 13 pages, 4 figures, accepted in ApJ Letters
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼Ð° ÑÐ°ÑÐ¿Ð¾Ð·Ð½Ð°Ð²Ð°Ð½Ð¸Ñ ÑÐµÐºÐ¾Ð¼Ð±Ð¸Ð½Ð°Ð½ÑÐ½ÑÑ ÑÐµÐ³Ð¼ÐµÐ½ÑÐ¾Ð² Ð² Ð¢-ÐºÐ»ÐµÑÐ¾ÑÐ½ÑÑ ÑÐµÑÐµÐ¿ÑÐ¾ÑÐ°Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Development of an algorithm for recognising recombination segments in T-cell receptors
Creators: name: ÐÐ°ÑÐ°ÑÐ¸Ð½Ð°, ÐÐºÐ°ÑÐµÑÐ¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2023
Subjects: ÑÐ¾ÑÐ¼Ð°Ð»ÑÐ½ÑÐµ ÑÐ·ÑÐºÐ¸
Ð¿Ð¾Ð¸ÑÐº Ð¿Ð°ÑÑÐµÑÐ½Ð¾Ð²
Ð¢-ÐºÐ»ÐµÑÐ¾ÑÐ½ÑÐµ ÑÐµÑÐµÐ¿ÑÐ¾ÑÑ
ÑÑÐ°Ð½ÑÐ»ÑÑÐ¸Ñ
formal languages
pattern search
T-cell receptors
translation

description: ÐÐ½Ð°Ð»Ð¸Ð· Ð¸Ð¼Ð¼ÑÐ½Ð½Ð¾Ð³Ð¾ ÑÐµÐ¿ÐµÑÑÑÐ°ÑÐ° Ð¢-ÐºÐ»ÐµÑÐ¾ÑÐ½ÑÑ ÑÐµÑÐµÐ¿ÑÐ¾ÑÐ¾Ð² -- Ð¾Ð´Ð½Ð° Ð¸Ð· Ð²Ð°Ð¶Ð½ÐµÐ¹ÑÐ¸Ñ Ð·Ð°Ð´Ð°Ñ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð¹ Ð¸Ð¼Ð¼ÑÐ½Ð¾Ð³ÐµÐ½Ð¾Ð¼Ð¸ÐºÐ¸. Ð¦ÐµÐ»ÑÑ Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐ»Ð°ÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼Ð° Ð¿Ð¾Ð¸ÑÐºÐ° Ð¿Ð°ÑÑÐµÑÐ½Ð¾Ð² Ð² Ð½ÑÐºÐ»ÐµÐ¾ÑÐ¸Ð´Ð½ÑÑ Ð¿Ð¾ÑÐ»ÐµÐ´Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾ÑÑÑÑ ÑÑÐ°ÑÑÐºÐ° CDR3. Ð ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ðµ Ð¿Ð¾Ð´ÑÐ¾Ð´Ñ Ðº ÑÐ°ÑÐ¿Ð¾Ð·Ð½Ð°Ð²Ð°Ð½Ð¸Ñ ÑÐµÐ³Ð¼ÐµÐ½ÑÐ¾Ð² ÑÐµÐºÐ¾Ð¼Ð±Ð¸Ð½Ð°ÑÐ¸Ð¸, Ð° ÑÐ°ÐºÐ¶Ðµ Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼Ð¾Ð², Ð¸ÑÐ¿Ð¾Ð»ÑÐ·ÑÑÑÐ¸ÑÑÑ Ð¿ÑÐ¸ Ð¿Ð¾Ð¸ÑÐºÐµ ÑÐµÐ³ÑÐ»ÑÑÐ½ÑÑ ÑÑÑÑÐºÑÑÑ Ð² ÑÐµÐºÑÑÐµ. ÐÐ¾ÑÑÐµÐ´ÑÑÐ²Ð¾Ð¼ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ° Ð´Ð»Ñ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° ÑÐµÐ¿ÐµÑÑÑÐ°ÑÐ° Ð¢-ÐºÐ»ÐµÑÐ¾ÑÐ½ÑÑ ÑÐµÑÐµÐ¿ÑÐ¾ÑÐ¾Ð² MiXCR Ð¸ Ð¿Ð°ÐºÐµÑÐ° Immunarch ÑÐ·ÑÐºÐ° R Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ð° Ð¿ÑÐµÐ´Ð²Ð°ÑÐ¸ÑÐµÐ»ÑÐ½Ð°Ñ Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² ÑÐµÐºÐ²ÐµÐ½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð´Ð»Ñ Ð·Ð°Ð¿ÑÑÐºÐ° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð½Ð¾Ð³Ð¾ Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼Ð°. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð². ÐÐ»Ð³Ð¾ÑÐ¸ÑÐ¼ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½ Ð½Ð° ÑÐ·ÑÐºÐµ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Python 3.9.2.
description: Analysis of the T-cell receptor immune repertoire is one of the most important tasks in modern immunogenomics. The aim of this work was to develop an algorithm for searching patterns in nucleotide sequences of the CDR3 region. Existing approaches to recognize the recombination segments and algorithms used in search of regular structures in text were considered. In order to run the developed algorithm, sequencing data was preprocessed using the MiXCR T-cell receptor repertoire analysis tool and the Immunarch package of the R language. The obtained results were analyzed. The algorithm was developed in the Python 3.9.2 programming language.
Heterologous production and functional characterization of Auxiliary Activity family 10 lytic polysaccharide monooxygenases for fiber functionalization
Creators: name: Li, James
Publisher: name: University of British Columbia
Year: 2022

description: The efficient depolymerization and/or utilization (valorization) of residual waste biomass is crucial for establishing a sustainable bio-based economy. Cellulose and chitin constitute the most abundant polymer components of biomass and represent renewable feedstocks for the production of biofuels, biomaterials, and other bio-based chemicals. The recalcitrance and low chemical reactivity of these polysaccharides limit their viability in numerous industrial applications. Lytic polysaccharide monooxygenases (LPMOs) are oxidative enzymes secreted by saprotrophic organisms to assist in the depolymerization of cellulose and chitin fibers. The recent discovery of LPMOs has shifted the fundamental understanding of microbial biomass utilization while also potentiating many avenues for the commercial valorization of cellulose and chitin. This dissertation presents a thorough investigation of the production, functional analysis, and fiber-modifying application of bacterial LPMOs from Auxiliary Activity family 10 (AA10). Signal peptide-mediated periplasmic secretion through the general secretion pathway (Sec) in Escherichia coli was the most suitable approach for producing active AA10 LPMOs. Five AA10s encoded by the historically significant Cellulomonas flavigena and Cellulomonas fimi bacteria were purified and characterized. Four of these Cellulomonas AA10 homologs were cellulose-active and one was chitin-active. Thermostability studies confirmed only cellulose-active Cellulomonas AA10s could reversibly unfold. Three non-Cellulomonas AA10 catalytic domains were produced in E. coli using the Sec signal peptide derived from the lone AA10 encoded by C. fimi. Notably, Xylanimonas cellulosilytica LPMO10A demonstrated dual activity on cellulose and chitin, while Streptomyces pratensis LPMO10D and Legionella longbeachae LPMO10 were found to be strictly active on chitin or cellulose substrates, respectively. Time course kinetic assays show high initial LPMO-oxidizing activity commonly coincides with rapid inactivation from oxidation. These results highlight the importance of optimizing abiotic parameters such as pH and reductant type to maximize the catalytic potential of LPMOs. Lastly, as a proof-of-concept, a C1-oxidizing cellulose-active AA10 encoded by C. flavigena was used to chemo-enzymatically conjugate several fluorescent probes to cellulose fibers. The work presented here informs future studies on heterologous LPMO production, LPMO activity screening and characterization, as well as LPMO-mediated fiber defibrillation and chemical modification.
On calculating the mean values of quantum observables in the optical tomography representation
Creators: name: Amosov, Grigori G.
name: Korennoy, Yakov A.
name: Man'ko, Vladimir I.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Given a density operator $\hat ρ$ the optical tomography map defines a one-parameter set of probability distributions $w_{\hat ρ}(X,ϕ),\ ϕ\in [0,2π),$ on the real line allowing to reconstruct $\hat ρ$. We introduce a dual map from the special class $\mathcal A$ of quantum observables $\hat a$ to a special class of generalized functions $a(X,ϕ)$ such that the mean value $_{\hat ρ} =Tr(\hat ρ\hat a)$ is given by the formula $_{\hat ρ}= \int \limits_{0}^{2π}\int \limits_{-\infty}^{+\infty}w_{\hat ρ}(X,ϕ)a(X,ϕ)dXdϕ$. The class $\mathcal A$ includes all the symmetrized polynomials of canonical variables $\hat q$ and $\hat p$.
description: 8 pages
Additional file 8 of Role of antiangiogenic agents in first-line treatment for advanced NSCLC in the era of immunotherapy
Creators: name: Pang, Lan-Lan
name: Gan, Jia-Di
name: Huang, Yi-Hua
name: Liao, Jun
name: Zhuang, Wei-Tao
name: Ali, Wael-Abdullah-Sultan
name: Hong, Shao-Dong
name: Zhang, Li
name: Fang, Wen-Feng
Publisher: name: figshare
Year: 2023
Subjects: Pharmacology
Biotechnology
Cancer
Science Policy

description: Additional file 8.