cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The targum (1962:Apr. 3 - 1962:Apr. 30)
Creators: name: No Name Supplied
Publisher: name: Targum Association
Year: 1962

description: Some University historians indicate that the Targum was first published as an annual in 1867, but of this we have no extant evidence. In January 1869, the Targum as we now know it, made its appearance as a monthly paper that concerned itself with student “literary contributions” and college news as well as serving as a vehicle for bringing news to alumni and the general public. The newspaper, which originally was for sale, varied in frequency over the years as did its title (The Targum, Rutgers Targum, Rutgers Daily Targum, and Daily Targum). The newspaper has continuously been published since 1869 with the exception of 19 months during the second world war, between February 1944 and October 1945. The Targum was published by the students of Rutgers College, and later Rutgers University—New Brunswick represented through the years as the Targum Association, Rutgers Targum Association, and Rutgers College Targum. As a student organization, the Targum operated under the oversight of the dean of students and student government but in October 1980, the Targum became an independent college paper.
The targum (1871:May)
Creators: name: No Name Supplied
Publisher: name: Targum Association
Year: 1871

description: Some University historians indicate that the Targum was first published as an annual in 1867, but of this we have no extant evidence. In January 1869, the Targum as we now know it, made its appearance as a monthly paper that concerned itself with student “literary contributions” and college news as well as serving as a vehicle for bringing news to alumni and the general public. The newspaper, which originally was for sale, varied in frequency over the years as did its title (The Targum, Rutgers Targum, Rutgers Daily Targum, and Daily Targum). The newspaper has continuously been published since 1869 with the exception of 19 months during the second world war, between February 1944 and October 1945. The Targum was published by the students of Rutgers College, and later Rutgers University—New Brunswick represented through the years as the Targum Association, Rutgers Targum Association, and Rutgers College Targum. As a student organization, the Targum operated under the oversight of the dean of students and student government but in October 1980, the Targum became an independent college paper.
Generalized Uncertainty Principle, Modified Dispersion Relation and Barrier penetration by a Dirac particle
Creators: name: Ghosh, Sumit
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We have studied the energy band structure of a Dirac particle in presence of a generalised uncertainty principle (GUP). We start from defining a modified momentum operator and derive corresponding modified dispersion relation (MDR) and GUP. Apart from the forbidden band within the range $\pm m$, $m$ being the mass of the particle, we find the existence of additional forbidden bands at the both ends of the spectrum. Such band structure forbids a Dirac particle to penetrate a potential step of sufficient height ($\sim E_P$, $E_P$ being Planck energy). This is also true for massless particle. Unlike the relativistic case, a massless particle also can reflect from a barrier of sufficient height. Finally we discuss about the Klein's paradox in presence of the GUP.
description: 10 pages, 7 figures, LaTex
Die externe Validität ”gematchter” Propensity-Score-Analysen - ein systematisches Review anhand eines Beispiels aus der Herzchirurgie
Creators: name: Redies, Lisa Angelika
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2014
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 615

description: In dieser Arbeit wurde untersucht, wie und ob Randomisierung bzw. Propensity-Score-Matching Studienkollektive einschränken und ob sich daraus grundsätzliche Aussagen zur externen Validität von Studien, die diese Verfahren anwenden, ableiten lassen. Des Weiteren wurde untersucht, inwieweit sich Kollektive durch Propensity-Score-Matching verändern. Es stellte sich heraus, dass die externe Validität von RCTs bezüglich der Ejektionsfraktion eingeschränkt ist. Die externe Validität "gematchter" Propensity-Score-Studien zeigte sich in keinem der geprüften Merkmale klinisch relevant eingeschränkt. Die "gematchten" Propensity-Score-Studien sind im vorliegenden systematischen Review den RCTs bezüglich ihrer externen Validität überlegen. Die externe Validität von "gematchten" Propensity-Score-Studien zeigt sich nicht eingeschränkt. Nachteilig jedoch bleibt, dass die interne Validität "gematchter" Propensity-Score-Studien im Gegensatz zu RCTs auf Grund von nicht zu garantierender Strukturgleichheit unsicher ist
description: In this doctoral thesis, I examined in how far two of these methods - randomization and Propensity Score Matching - restrict the selection of study collectives. I also asked whether such restrictions in uence the external validity of the respective study. Furthermore, I investigated in how far study collectives are altered by the process of Propensity Score Matching. My results illustrate that the external validity of the RCTs is affected when the left ventricular ejection fraction is measured. The external validity of matched Propensity Score studies was not affected in a clinically relevant way in any of the features examined. The matched Propensity Score studies proved superior to the randomized clinical trials in this systematic review concerning the external validity. The external validity of matched Propensity Score studies was not impaired. Nevertheless, a remaining disadvantage of matched Propensity Score studies was the fact that the internal validity, unlike in RCTs, remained unreliable due to the uncertain structural equality of both treatment groups.
The value of information for fisheries policy
Creators: name: Cisneros-Montemayor, Andrés M.
Publisher: name: University of British Columbia
Year: 2014

description: For policy-makers and managers, knowing what information to collect is just as important as collecting information. I apply economics-based methods, including the value of information approach, to natural resource management in order to identify new optimal policies and priority areas for investment. Explicitly incorporating uncertainty is key to these methods, both in formally acknowledging alternative hypothesis and strategies, and for selecting policies that are most robust to uncertainty about natural and social systems. Given their differences in objectives and current challenges, I develop and apply methods to both developing and developed marine fisheries. In Mexico, for example, I estimate that total fish catch over the last fifty years could be almost twice that reported in official data. This ‘informal’ catch reduces economic benefits from fisheries output, including informal processing and sales that add less value to production. Based on current monitoring investment and informal catch rates, I estimate that this represents an almost US$1 billion annual loss in foregone economic impacts, that could be partially gained by an annual investment of US$100 million to increase formalization of current catch. The benefits of assessing information value are not limited to developing fisheries or “data-poor” contexts. Linking ecosystem models with economic data and frameworks, I estimate that the supporting service value of forage fishes as food for other fished species vastly outweighs their yearly landed value (in the Southern Baja California Peninsula, US$180 million compared to US$62 million). For the California Current, which includes Mexico, the US and Canada, I couple game-theoretic and ecosystem models and find that moving beyond single-species valuation supports arguments for sustainable fishing of forage fishes, and creates incentives for cooperative fishing strategies across a range of climate scenarios. Aside from developing new and broadly applicable methods and frameworks, the overarching finding of this work is that it is always beneficial to formally and openly acknowledge uncertainty and alternative management strategies in natural resource assessments. This allows us to provide robust advice to policy-makers given, and not stymied by, uncertainty.
The mu - e Conversion in Nuclei, mu --> e gamma, mu --> 3e Decays and TeV Scale See-Saw Scenarios of Neutrino Mass Generation
Creators: name: Dinh, D. N.
name: Ibarra, A.
name: Molinaro, E.
name: Petcov, S. T.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We perform a detailed analysis of lepton flavour violation (LFV) within minimal see-saw type extensions of the Standard Model (SM), which give a viable mechanism of neutrino mass generation and provide new particle content at the electroweak scale. We focus, mainly, on predictions and constraints set on each scenario from mu --> e gamma, mu --> 3e and mu - e conversion in the nuclei. In this class of models, the flavour structure of the Yukawa couplings between the additional scalar and fermion representations and the SM leptons is highly constrained by neutrino oscillation measurements. In particular, we show that in some regions of the parameters space of type I and type II see-saw models, the Dirac and Majorana phases of the neutrino mixing matrix, the ordering and hierarchy of the active neutrino mass spectrum as well as the value of the reactor mixing angle theta_{13} may considerably affect the size of the LFV observables. The interplay of the latter clearly allows to discriminate among the different low energy see-saw possibilities.
description: Expressions for the factors |C_{me}|^2 and |C_{mu3e}|^2 in the mu-e conversion and mu-->3e decay rates, eqs. (36) and (49), respectively, corrected; results in subsections 2.2 and 2.3 quantitatively changed, qualitatively remain the same; figures 2, 3, 4 and 5 replaced
Additional file 1 of On using a double-thin-shell approach and TEC perturbation component to sound night-time mid-latitude E–F coupling
Creators: name: Fu, Weizheng
name: Yokoyama, Tatsuhiro
name: Ssessanga, Nicholas
name: Yamamoto, Mamoru
name: Liu, Peng
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Fig.S1. 2-D maps of input irregularities only in E shell (a–b), output irregularities (c–d), and corresponding residual distribution (e). 2-D maps of input irregularities only in F shell (f–g), output irregularities (h–i), and corresponding residual distribution (j).
ε-Strong simulation of the Brownian path
Creators: name: Beskos, Alexandros
name: Peluchetti, Stefano
name: Roberts, Gareth
Publisher: name: arXiv
Year: 2011
Subjects: subject: Computation (stat.CO)
subject: Statistics Theory (math.ST)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: We present an iterative sampling method which delivers upper and lower bounding processes for the Brownian path. We develop such processes with particular emphasis on being able to unbiasedly simulate them on a personal computer. The dominating processes converge almost surely in the supremum and $L_1$ norms. In particular, the rate of converge in $L_1$ is of the order $\mathcal {O}(\mathcal{K}^{-1/2})$, $\mathcal{K}$ denoting the computing cost. The a.s. enfolding of the Brownian path can be exploited in Monte Carlo applications involving Brownian paths whence our algorithm (termed the $\varepsilon$-strong algorithm) can deliver unbiased Monte Carlo estimators over path expectations, overcoming discretisation errors characterising standard approaches. We will show analytical results from applications of the $\varepsilon$-strong algorithm for estimating expectations arising in option pricing. We will also illustrate that individual steps of the algorithm can be of separate interest, giving new simulation methods for interesting Brownian distributions.
description: Published in at http://dx.doi.org/10.3150/11-BEJ383 the Bernoulli (http://isi.cbs.nl/bernoulli/) by the International Statistical Institute/Bernoulli Society (http://isi.cbs.nl/BS/bshome.htm)
Untersuchung und Charakterisierung von Inhibitoren des P-Glykoproteins zur Überwindung der Multidrug Resistance
Creators: name: Brandt, Tobias
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2008
Subjects: subject: Elektronische Publikation
subject: Hochschulschrift
subject: Online-Publikation
subject: Zsfassung in engl. Sprache
subject: 615.1

description: Das Phänomen der Multidrug Resistance (MDR) von Tumorzellen wird seit über 30 Jahren intensiv untersucht. Als hauptverantwortlich für die Resistenzerscheinungen wurden einige Mitglieder der ABC-Transporter-Familie identifiziert, von denen das P-Glykoprotein (P-gp) im Mittelpunkt dieser Arbeit steht. Neben weiteren Ansätzen zur Überwindung der MDR gibt es nach wie vor Bemühungen die Aktivität der Transportproteine durch Inhibitoren bzw. Modulatoren zu beeinflussen. Das Ziel der vorliegenden Arbeit war die Testung zahlreicher Verbindungen mit potentiell MDR-modulatorischer Wirksamkeit. Dazu gehörten in erster Linie Phenothiazinderivate, aber auch Carbazol- oder Dibenzazepinverbindungen, sowie neuartige 2,2-Diphenyl-1,3-dioxolane und 4,5-Diphenyl-1,3-dioxolane. Zur Bestimmung der modulatorischen Potenz wurden in vitro verschiedene Wirkwerte an LLC-PK1 und LLC-MDR1 Zellen ermittelt. Dazu gehörten die mit Hilfe von Zytotoxizitätstests ermittelten Fold Reversal und der modulatorische Quotient der Verbindungen. Zur Auswertung wurde der Kristallviolett-Test verwendet, der sich als äquivalent zum Neutralrot- bzw. Sulforhodamin B-Test erwies. Zusätzlich wurden ausgewählte Substanzen am Durchflusszytometer vermessen, wobei die vorherigen Ergebnisse bestätigt werden konnten. Im Anschluss an diese Untersuchungen wurden erste Struktur-Wirkungs-Beziehungen untersucht und ein erster Vergleich mit bekannten Pharmakophormodellen durchgeführt.
description: The phenomenon of multidrug resistance has been investigated intensively for more than 30 years. As mainly responsible for the occurance of resistances some members of the ABC-transporter familiy could be identified, of whom the p-glycoprotein is in the focus of this thesis. Beside other approaches to overcome multidrug resistance there are still efforts to alter the activity of transport proteins by inhibitors or modulators. The aim of this study was the testing of numerous compounds with potential mdr-modulating properties. These testings included primarily phenothiazines but also carbazole and dibenzazepine structures and novel 2,2-diphenyl-1,3-dioxolane and 4,5-diphenyl-1,3-dioxolanes. For the determination of the modulatoric potency several values of action were determined on LLC-PK1 and LLC-MDR1 cells. These included the fold reversal and the modulatoric quotient of the compounds. The examinations were done with the crystal violet assay which showed to be equal to neutral red and sulforhodamine B assays. Some selected compounds were additionally examined using the fluorescene activated cell sorter, which confirmed the former results. Following the investigations initial quantitative structure-activiy relationsships were discussed and a first comparison with known pharmacophore models was made.
Dehn function and asymptotic cones of Abels' group
Creators: name: Cornulier, Yves
name: Tessera, Romain
Publisher: name: arXiv
Year: 2012
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20F65 (Primary) 20F69, 20F16, 20F05, 22D05, 51M25 (Secondary)

description: We prove that Abels' group over an arbitrary nondiscrete locally compact field has a quadratic Dehn function. As applications, we exhibit connected Lie groups and polycyclic groups whose asymptotic cones have uncountable abelian fundamental group. We also obtain, from the case of finite characteristic, uncountably many non-quasi-isometric finitely generated solvable groups, as well as peculiar examples of fundamental groups of asymptotic cones.
description: 34 pages, no figure (v2: various corrections and minor improvements especially in the last section)
Homological dimensions and abelian model structures on chain complexes
Creators: name: Pérez, Marco
Publisher: name: arXiv
Year: 2012
Subjects: subject: Category Theory (math.CT)
subject: FOS: Mathematics

description: We construct Abelian model structures on the category of chain complexes over a ring $R$, from the notion homological dimensions of modules. Given an integer $n > 0$, we prove that the left modules over a ringoid $\mathfrak{R}$ with projective dimension at most $n$ form the left half of a complete cotorsion pair. Using this result we prove that there is a unique Abelian model structure on the category of chain complexes where the exact complexes are the trivial objects and the complexes with projective dimension at most $n$ form the class of trivially cofibrant objects. In the paper "Cotorsion pairs in C($R$-Mod)", the authors construct an Abelian model structure on chain complexes, where the trivial objects are the exact complexes and the class of cofibrant objects is given by the complexes whose terms are all projective. We extend this result by finding a new Abelian model structure with the same trivial objects and where the cofibrant objects are given by the class of complexes whose terms are modules with projective dimension at most $n$. We also prove similar results concerning the flat dimension.
description: Fifth version, 38 pages. Some typos were corrected
Thermodynamics of black plane solution
Creators: name: Rodrigues, Manuel E.
name: Jardim, Deborah F.
name: Houndjo, M. J. S.
name: Myrzakulov, Ratbay
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We obtain a new phantom black plane solution in 4D of the Einstein-Maxwell theory coupled with a cosmological constant. We analyse their basic properties, as well as its causal structure, and obtain the extensive and intensive thermodynamic variables, as well as the specific heat and the first law. Through the specific heat and the so-called geometric methods, we analyse in detail their thermodynamic properties, the extreme and phase transition limits, as well as the local and global stabilities of the system. The normal case is shown with an extreme limit and the phantom one with a phase transition only for null mass, which is physically inaccessible. The systems present local and global stabilities for certain values of the entropy density with respect to the electric charge, for the canonical and grand canonical ensembles.
description: 19 pages, 3 figures, version accepted for publication in General Relativity and Gravitation
A Frobenius-type theorem for singular Lipschitz distributions
Creators: name: Montanari, Annamaria
name: Morbidelli, Daniele
Publisher: name: arXiv
Year: 2011
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53C12

description: We prove a Frobenius-type theorem for singular distributions generated by a family of locally Lipschitz continuous vector fields satisfying almost everywhere a quantitative finite type condition.
Sanierung eines umweltgeschädigten, historischen Wirtschaftsgebäudes am Gut Lomnitz/Lomnica als modellhafte Maßnahme zur Bewahrung der historischen Kulturlandschaft des Hirschberger Tales (Schlesien/Polen)
Creators: name: Küster, Elisabeth Von
name: Röhner, Ellen
name: Treziak, Ulrike
Publisher: name: VSK und Stiftung Dominium Lomnitz
Year: 2008
Subjects: Restoration

description: Das Projekt “Sanierung des historischen Pferdestalls“ kann nach etwa einjähriger Dauer sowohl in technischer, als auch in denkmalpflegerischer und ästhetischer Hinsicht als sehr gelungen betrachtet werden. Das alte Stallgebäude ist mit seiner historischen Farbgebung und Dachziegeleindeckung in seiner ursprünglichen Schönheit wieder entstanden, der vorherige Zustand erheblicher Baufälligkeit und Verwahrlosung ist vollständig beseitigt. Trotz der übrigen noch im Verfall befindlichen Gebäude hat der Gutshof durch den renovierten Pferdestall einen wesentlichen Teil seiner ursprünglichen Ausstrahlung zurück gewonnen. Hierzu trägt zudem die von einer etwa 80 cm starken Schutt- und Schlackeschicht befreite und wiederhergestellte Hoffläche bei, denn die Aufschüttungen hatten die Proportionen des Gebäudes erheblich beeinträchtigt. Nicht zuletzt bereichern die neu gepflanzten Hofbäume und der an historischer Stelle neu angelegte Gutsteich das positive Bild der Gesamtanlage.
Untersuchungen zum Mechanismus der Penetrationserhöhung durch Mikroemulsionen und neue Enhancer bei der dermalen Applikation von Wirkstoffen
Creators: name: Heuschkel, Sandra
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2009
Subjects: subject: Pharmakologie
subject: Arzneistoffträger
subject: Enhancer
subject: Online-Publikation
subject: Hochschulschrift
subject: 615.6
subject: 616

description: Die äußerste Hautschicht, das Stratum corneum, stellt für die dermale Arzneistoffaufnahme häufig eine Barriere dar. Mit Hilfe verschiedener galenischer Ansätze, u.a. der Verwendung von Mikroemulsionen, ist es möglich, diese effektiv zu überwinden. In In-vitro-Studien an künstlichen Membranen und humanem Stratum corneum wurden die transepidermalen Penetrationsprozesse einer zuvor ausführlich physikochemisch charakterisierten Mikroemulsion detailliert untersucht. Durch die simultane Erfassung der Penetration mehrerer Formulierungsbestandteile auf nicht-invasive Weise mit Hilfe einer FTIR-ATR-Diffusionszelle konnten im Verlauf der Penetration stattfindende Veränderungen in Verteilungsverhalten und Solubilisierungskapazität der Membranen als wichtige mechanistische Faktoren ausgemacht werden. In vitro an Vollhaut gefundene Hinweise auf eine Beteiligung der follikulären Route an der Penetration konnten in vivo im Rahmen einer klinischen Pilotstudie an Freiwilligen untermauert werden. Einen weiteren Schwerpunkt der Arbeit stellte der Einsatz höherer 1,2-Alkandiole in dermal applizierbaren Vehikeln dar. Ihr Zusatz zu klassischen halbfesten Zubereitungen bewirkte in vitro eine effektive Steigerung (epi-)dermaler Wirkstoffkonzentrationen, während neu entwickelte alkandiolhaltige Mikroemulsionen auf Basis eines Weizenproteintensides eine signifikant erhöhte Permeation zeigten.
Algebraic cycles and fibrations
Creators: name: Vial, Charles
Publisher: name: arXiv
Year: 2012
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14C15, 14C25, 14C05, 14D99

description: Let $f : X -> B$ be a projective surjective morphism between quasi-projective varieties. The goal of this paper is the study of the Chow groups of $X$ in terms of the Chow groups of $B$ and of the fibers of $f$. One of the applications concerns quadric bundles. When $X$ and $B$ are smooth projective and when $f$ is a flat quadric fibration, we show that the motive of $X$ is "built" from the motives of varieties of dimension less than the dimension of $B$.
description: Supersedes arXiv:1203.2650
Ergebnisse und Analyse der primären perkutanen Strahlentherapie des Uteruszervixkarzinoms in Kombination mit HDR-Brachytherapie
Creators: name: Utzig, Dorothea
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2010
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 615

description: Es erfolgte die retrospektive Analyse der primäre Strahlentherapie des Zervixkarzinoms zur Beurteilung von 5-Jahres-Überleben, Rezidivhäufigkeit und Nebenwirkungsrate. Von 1987-1995 wurden 443 Frauen mit inoperablen Zervixkarzinomen, mittleres Alter 58 Jahre, kurativ mit einer Hochvolt-HDR-Afterloading-Therapie behandelt. Es wurden 45 Gy als perkutane Hochvolttherapie (Punkt B) in Form einer biaxialen Pendelung bzw. mit Mittelblock ab 20 Gy und 5 x 7 Gy (Punkt A) HDR-Afterloading intrauterin appliziert. Die 5-Jahresüberlebenszeit war für alle Patientinnen 62 %. Fortgeschrittenes Tumorstadium, schlechtes Grading und junges Alter stellten einen ungünstigen Prognosefaktor dar. 21 % aller Frauen wiesen 6 Monate nach Therapie eine persistierende bzw. progrediente Erkrankung auf. Das rezidivfreie 5 Jahres Überleben für Patientinnen mit kompletter Remission betrug im Stad.I 85  4 %, im Stad.II 74  4 %, im Stad.III 64  4 % und im Stad.IV 44  22 %. Die Rate der Spätkomplikationen Grad III und IV n. EORTC war 6,3 % für Darm- und 2,3 % für Blasentoxizität. Die Ergebnisse zeigen ein gutes Ansprechen auf Strahlentherapie mit HDR-Afterloading.
Nonparametric inference on Lévy measures and copulas
Creators: name: Bücher, Axel
name: Vetter, Mathias
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: In this paper nonparametric methods to assess the multivariate Lévy measure are introduced. Starting from high-frequency observations of a Lévy process $\mathbf{X}$, we construct estimators for its tail integrals and the Pareto-Lévy copula and prove weak convergence of these estimators in certain function spaces. Given n observations of increments over intervals of length $Δ_n$, the rate of convergence is $k_n^{-1/2}$ for $k_n=nΔ_n$ which is natural concerning inference on the Lévy measure. Besides extensions to nonequidistant sampling schemes analytic properties of the Pareto-Lévy copula which, to the best of our knowledge, have not been mentioned before in the literature are provided as well. We conclude with a short simulation study on the performance of our estimators and apply them to real data.
description: Published in at http://dx.doi.org/10.1214/13-AOS1116 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)
The Pure Virtual Braid Group Is Quadratic
Creators: name: Lee, Peter
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Algebra (math.QA)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: If an augmented algebra K over Q is filtered by powers of its augmentation ideal I, the associated graded algebra grK need not in general be quadratic: although it is generated in degree 1, its relations may not be generated by homogeneous relations of degree 2. In this paper we give a sufficient criterion (called the PVH Criterion) for grK to be quadratic. When K is the group algebra of a group G, quadraticity is known to be equivalent to the existence of a (not necessarily homomorphic) universal finite type invariant for G. Thus the PVH Criterion also implies the existence of such a universal finite type invariant for the group G. We apply the PVH Criterion to the group algebra of the pure virtual braid group (also known as the quasi-triangular group), and show that the corresponding associated graded algebra is quadratic, and hence that these groups have a (not necessarily homomorphic) universal finite type invariant.
description: 53 pages, 15 figures. Some clarifications added and inaccuracies corrected, reflecting suggestions made by the referee of the published version of the paper
title: Umweltbedingte Pigmentveränderungen der gotischen Ausmalungen in der Burg Ziesar und der Marienkirche Herzberg
title: Entwicklung eines Konzeptes zur nachhaltigen Konservierung
titleType: Subtitle
Creators: name: Schlütter, Frank
Publisher: name: NN
Year: 2009
Subjects: Conservation science

description: In diesem Thesenpapier wird eine Systematisierung der beobachteten Pigmentveränderungen und der vermuteten Schädigungsprozesse vorgestellt. Diese Einteilung basiert auf visuellen Gesichtspunkten sowie auf den Ergebnissen mikroskopischer und mikrochemischer Untersuchungen sowie der µ-RFA und der Raman-Spektroskopie. In weiterführenden restauratorischen und naturwissenschaftlichen Untersuchungen sollen die maßgeblichen physikalischen, chemischen und mineralogischen Abläufe unter Berücksichtigung der objektspezifischen Gegebenheiten ermittelt werden.

Das Projekt bietet die Möglichkeit, eine Vielzahl von Pigmentveränderungen an Wandmalereien unter besonderer Berücksichtigung schädigender Umwelteinflüsse und der Bauwerksgegebenheiten (Klima, Mikrobiologie, Salze) systematisch zu untersuchen. Es sind allgemeingültige Ergebnisse zu erwarten, die auf vergleichbare Phänomene an anderen Wandmalereien übertragen werden können. Der streng praxisorientierte Forschungsansatz dient der Klärung bisher nicht bekannter oder nicht ausreichend berücksichtigter Zusammenhänge zwischen Bauwerksgegebenheiten und Pigmentumwandlungen
Many faces of Albus Dumbledore in the setting of fan writing : the transformation of readers into “reader-writers” and the implications of their presence in the age of online fandom
Creators: name: Fujita, Midori
Publisher: name: University of British Columbia
Year: 2014

description: This thesis examines the dynamic and changing nature of reader response in the time of online fandom by examining fan reception of, and response to, the character Dumbledore in J.K. Rowling’s Harry Potter series. Using the framework of reader reception theory established by Wolfgang Iser, in particular Iser’s conception of textual indeterminacies, to construct my critical framework, this work examines Professor Albus Dumbledore as a case study in order to illuminate and explore how both the text and readers may contribute to the identity formation of a single character. The research examines twenty-one selected Internet-based works of fan writing. These writings are both analytical and imaginative, and compose a selection that illuminates what aspect of Dumbledore’s characters inspired readers’ critical reflection and inspired their creative re-construction of the original story. This thesis further examines what the flourishing presence of Harry Potter fan community tells us about the role technological progress has played and is playing in reshaping the dynamics of reader response. Additionally, this research explores the blurring boundaries between authors and readers in light of the blooming culture of fan fiction writing. The themes that Harry Potter fan writers have addressed imply that subjects of morality, sexuality, failures, amend-making, and questions of individual agency versus societal constraints are important issues with which contemporary readers of Harry Potter stories are drawn to explore. Harry Potter, by virtue of being one of the most fervently read text in the last decade provides a valuable insight what reading and literature may mean to ordinary people in their everyday lives.
Supplementary Table 1: from Individual differences in decision-making: evidence for the scarcity hypothesis from the English Longitudinal Study of Ageing
Creators: name: Tunney, Richard J.
name: James, Richard J. E.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: 179999 Psychology and Cognitive Sciences not elsewhere classified
subject: FOS: Psychology

description: The 2010 English Indices of Deprivation. Details on how these are combined are available from: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/6320/1870718.pdf
title: Recommendations for the Preservation of Wax Moulages at Universities and Hospitals and in Museums and Other Collections
title: RWax Moulages: A Valuable Handicraft Threatened with Extinction
titleType: AlternativeTitle
Creators: name: Lang, Johanna
name: Mühlenberend, Sandra
name: Roeßiger, Susanne
Publisher: name: Deutsches Hygiene-Museum Dresden
Year: 2010
Subjects: Preventive Conservation

description: In February, 2008, the German Federal Cultural Foundation, together with the Cultural Foundation of the German States, initiated the KUR programme for the conservation and restoration of endangered cultural artefacts. Museums, archives and libraries submitted 121 proposals, from which a jury selected 26 projects dealing with important specimens for cultural history that urgently require conservatorial and/or restorational care.

The Deutsches Hygiene-Museum Dresden (DHMD) holds one of the world's largest collections of wax moulages, comprising 2000 lifelike representations of pathological symptoms. European museums and universities still have collections of moulages of great value to cultural and medical history. Under the KUR programme, the DHMD in cooperation with other renowned institutions will develop a new technique for the conservation and restoration of these specimens and apply it on its own collection. The objective is to develop general standards and guidelines for the conservation and restoration of moulages, as well as an internet-based training course for restorers.
Area products for stationary black hole horizons
Creators: name: Visser, Matt
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Area products for multi-horizon stationary black holes often have intriguing properties, and are often (though not always) independent of the mass of the black hole itself (depending only on various charges, angular momenta, and moduli). Such products are often formulated in terms of the areas of inner (Cauchy) horizons and outer (event) horizons, and sometimes include the effects of unphysical "virtual" horizons. But the conjectured mass-independence sometimes fails. Specifically, for the Schwarzschild-de Sitter [Kottler] black hole in (3+1) dimensions it is shown by explicit exact calculation that the product of event horizon area and cosmological horizon area is not mass independent. (Including the effect of the third "virtual" horizon does not improve the situation.) Similarly, in the Reissner-Nordstrom-anti-de Sitter black hole in (3+1) dimensions the product of inner (Cauchy) horizon area and event horizon area is calculated (perturbatively), and is shown to be not mass independent. That is, the mass-independence of the product of physical horizon areas is not generic. In spherical symmetry, whenever the quasi-local mass m(r) is a Laurent polynomial in aerial radius, r=sqrt{A/4π}, there are significantly more complicated mass-independent quantities, the elementary symmetric polynomials built up from the complete set of horizon radii (physical and virtual). Sometimes it is possible to eliminate the unphysical virtual horizons, constructing combinations of physical horizon areas that are mass independent, but they tend to be considerably more complicated than the simple products and related constructions currently being mooted in the literature.
description: V1: 16 pages; V2: 9 pages (now formatted in PRD style). Minor change in title. Extra introduction, background, discussion. Several additional references; other references updated. Minor typos fixed. This version accepted for publication in PRD; V3: Minor typos fixed. Published version
Protometrics
Creators: name: Deza, Michel
name: Chebotarev, Pavel
Publisher: name: arXiv
Year: 2011
Subjects: subject: Metric Geometry (math.MG)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 54E35, 51Fxx, 31E05, 15B48

description: We introduce the concept of protometric and present some properties of protometrics.
description: 4 pages. Submitted to the Special ISMVL Session in honour of Prof. Ivo G. Rosenberg. In this version, a minor correction made
title: Schadstoffe im Museum
title: Untersuchung der am häufigsten verwendeten Materialien in der Museumspraxis zur Erarbeitung einer Materialdatenbank "Positiv-Liste" und standardisierten Hilfsplänen.
titleType: Subtitle
Creators: name: Löwe, Jessica
Publisher: name: NN
Year: 2010
Subjects: Conservation science

description: Vorläufig erster Entwurf einer Projektskizze, zur zukünftigen Umsetzung gedacht, zum Thema Schadstoffe im Museumsbetrieb mit Literatursammlung.
Ziel soll die Untersuchung der am häufigsten verwendeten Materialien in der Museumspraxis zur Erarbeitung einer Materialdatenbank 'Positiv-Liste' sein.
Dieser Entwurf kann sich im Laufe der Zeit zukünftig noch ändern bzw. er wird evtl. erweitert werden.

Inhaltsübersicht
1. Grundlegendes zur Thematik
1.1 Gefahrenpotentiale im Museum durch Schadstoffe
1.2 Einordnung und Bewertung
1.3 Die Schadstoffe

2. Ziele der Projektarbeit
2.1 Ziele
2.2 Schwerpunkte

3. Konzept zur Durchführung
3.1 Konzept und Ablauf
3.2 Benötigte Ausstattung/Materialien
3.3 Zeit und Kosten

4. Anhang
4.1 Literatur
4.2 Weblinks
Tumorzelllinien spezifische Aufnahme von HPMA basierten Wirkstoffträgern
Creators: name: Gündel, Daniel
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2018
Subjects: subject: HPMA; Hypoxie; Azidose; pH; pO2; Wirkstofftransporter; Endozytose; Polymer; Walker-256; AT-1
subject: HPMA; hypoxia; acidosis; pH; pO2; drug carrier; endocytosis; polymer; Walker-256; AT-1
subject: 615

description: In dieser Arbeit wurden makromolekulare Wirkstoffträger basierend auf N-(2-Hydroxypropyl)methacrylamid (pHPMA) hinsichtlich ihrer Aufnahme in die Tumorzelllinien AT-1 und Walker-256 untersucht. Es wurden dafür je eine kurze und längere Polymerkette von strukturell verschiedenen pHPMA-Varianten (Homopolymere, Random-Copolymere, Block-Copolymere) näher betrachtet. In Vorversuchen wurde gezeigt, dass diese sich hinsichtlich der Biodistribution und Tumorakkumulation in beiden Tumormodellen der Ratte unterschieden. Darum wurden zunächst diese beiden Tumormodelle in vivo näher hinsichtlich der Gefäßdichte, des pO2, des extrazellulären pH-Wertes und weiterer Parameter charakterisiert. In Zellkulturversuchen wurde dann der Einfluss eines hypoxischen und azidotischen Milieus auf die Aufnahme der Polymere in beide Zelllinien untersucht. Zudem wurden mögliche Endozytosewege der Polymere durch Inhibitorstudien und der Einfluss der Hypoxie und Azidose auf diese Endozytosewege näher betrachtet.
description: In this study, macromolecular drug carriers based on N-(2-hydroxypropyl)methacrylamide (pHPMA) were investigated for their uptake into the tumor cell lines AT-1 and Walker-256. A short and a longer polymer chain of structurally different pHPMA variants (homopolymers, random copolymers, block copolymers) were examined in detail. In preliminary experiments, it was shown that these differed in terms of biodistribution and tumor accumulation in both rat tumor models. Therefore, these two tumor models were characterized in vivo with respect to vessel density, pO2, extracellular pH and other parameters. In cell culture experiments, the impact of a hypoxic and acidotic environment on the uptake of polymers in both cell lines was determined. In addition, possible endocytosis pathways of the polymers were investigated by inhibitor studies and the impact of hypoxia and acidosis on these endocytosis pathways.
Statine aktivieren die transkriptionelle und translationale Expression des antioxidativen Enzyms Hämoxygenase-1 in Endothelzellen
Creators: name: Hemmerle-Kock, Anke
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2010
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 615.5

description: Cholesterol- unabhängige pleiotrope Effekte von Statinen führen zu antiinflammatorischen und antioxidativen Wirkungen deren Mechanismus bislang noch nicht vollständig geklärt ist. Diese Studie untersucht die potentielle protektive Beteiligung der Hämoxygenase-1 als Zielstruktur von Statinen bei einer vaskulären Dysfunktion. In kultivierten Endothelzellen induzierten Statine die HO-1 mRNA und das Protein konzentrations- und zeitabhängig. Die Luciferaseaktivität eines Reportergenkonstruktes des HO-1 Promotors wurde durch Statine induziert, was auf eine Beteiligung von Transkriptionsfaktoren hindeutet. Die Vorbehandlung von Endothelzellen mit Statinen führte zu einer reduzierten Bildung von reaktiven Sauerstoffspezies nach NADPH-Inkubation. Diese Ergebnisse zeigen, dass das antioxidative Stressprotein Hämoxygenase-1 in Endothelzellen eine Zielstruktur für Statine darstellt und so zu den antioxidativen, antiinflammatorischen und antiatherogenen Effekten dieser Substanzen beitragen kann.
Supplementary Table 3: from Individual differences in decision-making: evidence for the scarcity hypothesis from the English Longitudinal Study of Ageing
Creators: name: Tunney, Richard J.
name: James, Richard J. E.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: 179999 Psychology and Cognitive Sciences not elsewhere classified
subject: FOS: Psychology

description: Principal component loadings for the index of cognitive function.
Scaling relations for galaxy clusters in the Millennium-XXL simulation
Creators: name: Angulo, R. E.
name: Springel, V.
name: White, S. D. M.
name: Jenkins, A.
name: Baugh, C. M.
name: Frenk, C. S.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present a very large high-resolution cosmological N-body simulation, the Millennium-XXL or MXXL, which uses 303 billion particles to represent the formation of dark matter structures throughout a 4.1Gpc box in a LambdaCDM cosmology. We create sky maps and identify large samples of galaxy clusters using surrogates for four different observables: richness estimated from galaxy surveys, X-ray luminosity, integrated Sunyaev-Zeldovich signal, and lensing mass. The unprecedented combination of volume and resolution allows us to explore in detail how these observables scale with each other and with cluster mass. The scatter correlates between different mass-observable relations because of common sensitivities to the internal structure, orientation and environment of clusters, as well as to line-of-sight superposition of uncorrelated structure. We show that this can account for the apparent discrepancies uncovered recently between the mean thermal SZ signals measured for optically and X-ray selected clusters by stacking data from the Planck satellite. Related systematics can also affect inferences from extreme clusters detected at high redshift. Our results illustrate that cosmological conclusions from galaxy cluster surveys depend critically on proper modelling, not only of the relevant physics, but also of the full distribution of the observables and of the selection biases induced by cluster identification procedures.
description: 19 pages, 12 figures. Replaced with version published in MNRAS
Daftar, Semak dan Kemas Kini Data Menerusi PADU Mulai Hari Ini
Creators: name: Ating, Rashid
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 390107
subject: Humanities and social sciences curriculum and pedagogy (excl. economics, business and management)
classificationCode: 460105
subject: Applications in social sciences and education
classificationCode: 500206
subject: History and philosophy of the social sciences

description: Putrajaya - Individu yang berumur 18 tahun ke atas perlu membuat semakan data di laman sesawang Pangkalan Data Utama (PADU), mengemas kini 39 maklumat dan mengesahkan maklumat tersebut mulai hari ini selepas selesai pelancarannya
Development, optimisation and application of in vitro and in vivo microdialysis methods contributing to characterise drug disposition processes
Creators: name: Simmel, Franziska
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2010
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 615

description: Die Mehrzahl der Infektionen ist extrazellulär, d.h. in der Interstitialflüssigkeit (ISF), lokalisiert. Die Mikrodialyse (MD) stellt die Methode der Wahl dar, den direkten Zugang zum Interstitium zu ermöglichen, um dort lokale, ungebundene und somit pharmakodynamisch aktive Arzneistoffkonzentrationen zu bestimmen. Im Rahmen dieser Arbeit wurde in vier Projekten die Pharmakokinetik (PK) von Voriconazol (VRC), einem Antimykotikum, welches hauptsächlich für kritisch Kranke mit invasiven Aspergillosen und Candidosen vorgesehen ist, am Infektionsort (d.h. im ISF) mittels MD untersucht. Zunächst wurde eine analytische HPLC-Methode zur Quantifizierung von VRC aus verschiedenen Matrizes entwickelt und validiert. Die Entwicklung und nachfolgende Anwendung eines In-vitro-MD-Systems demonstrierte die generelle Eignung von VRC für die MD. In einem nächsten Schritt wurde die MD nach oraler Mehrfachdosis von VRC in gesunder und infizierter Haut von gesunden Meerschweinchen durchgeführt. Im Ergebnis stand die Hypothese, dass eine Infektion die PK von VRC in dieser Matrix nicht zu beeinflussen scheint. Der Vergleich mit ungebundenen Konzentrationen im Blut zeigte, dass VRC gut ins ISF penetrierte und Konzentrationen oberhalb der MHK diverser Pilzpathogene erreicht wurden. Schließlich wurde ein spezielles Setting für reproduzierbare, über mehrere Tage dauernde, In-vivo-MD-Untersuchungen entwickelt und dessen Anwendung als machbar und tolerabel für Probanden im Rahmen einer Pilotstudie (Teil I) belegt. Diese Untersuchung wurde als prospektive, zweiteilige, offene, unkontrollierte Studie mit sequenzieller Mehrfachgabe von VRC geplant. Ein hervorragendes Penetrationsvermögen ins ISF und demzufolge die Verteilung in sowie Verfügbarkeit am potentiellen Wirkort konnte für VRC gezeigt werden. Die hohe und über die Zeit ansteigende interindividuelle Variabilität der PK konnte zum Teil unter Berücksichtigung des Genotyps der hauptsächlichen, VRC-metabolisierenden Cytochrom P450-Enzyme jedes Studienteilnehmers erklärt werden. Folgeuntersuchungen (Teil II; in Patienten) werden weiter dazu beitragen die Disposition von VRC zu charakterisieren und die Ableitung zukünftiger, potentiell genotyp-spezifischer Dosierungsempfehlungen ermöglichen mit dem Ziel einer individualisierten, effektiven und zugleich sicheren Arzneimitteltherapie.
Supplementary Table 2: from Individual differences in decision-making: evidence for the scarcity hypothesis from the English Longitudinal Study of Ageing
Creators: name: Tunney, Richard J.
name: James, Richard J. E.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: 179999 Psychology and Cognitive Sciences not elsewhere classified
subject: FOS: Psychology

description: Number of data points for index of multiple deprivation and socio-economic classification.
Konzept zum Erhalt, zur Sicherung und zur behutsamen Entwicklung des Bestandes der Kirchenburg und der Nebenanlagen
Creators: name: Hülsemann, Jan
name: Lemnitz, Henriette
name: Faitsch, Joachim
Publisher: name: NN
Year: 2011
Subjects: Conservation Restoration

description: Der Bericht umfasst eine erste Einschätzung und Bewertung zum derzeitigen Erhaltungszustand des Kirchenburgenensembles Birthälm mit dem Ziel, den Bestand zu sichern und dauerhaft zu erhalten. Es wird ein bestandsschonender, werk- und materialgetreuer Ansatz für das Maßnahmenkonzept entwickelt, in dem Aspekte der Denkmalpflege und des Naturschutzes auf dem Stand der Technik zusammengeführt werden. Hinzu kommen Anforderungen zur Wirtschaftlichkeit. Mit den Touristenströmen in das UNESCO-Kulturerbe ist ein großes Potential zu nachhaltiger Wirtschaftlichkeit bereits vorhanden, aber bei weitem nicht erschöpft. Das Angebot für Besucher soll noch attraktiver gestaltet und ausgeweitet werden.

Die hier dokumentierten Planungen dienen als Grundlage für weitere Schritte, insbesondere für das erforderliche Genehmigungsverfahren. Behandelt werden:
- dringend notwendige Instandsetzungen/ Maßnahmen zur Stand- und Verkehrssicherheit
- Konservierungs- und Restaurierungsmaßnahmen
- Modernisierungen und Nutzungskonzepte für einzelne Teile der Anlage

Das Dokument vom 06.03.2011 entstand im Vorfeld des von der Deutschen Stiftung Umwelt (DBU) geförderten Projekts "Modellhafte Instandsetzung der anthropogen umweltgeschädigten Bischofskirchenburg zu Birthälm/Siebenbürgen unter Beachtung von Naturschutzzielen (UNESCO-Welterbe)".