cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Circular RNAs: biology and clinical significance of breast cancer
Creators: name: Wang, Zhanwei
name: Deng, Hao
name: Jin, Yao
name: Luo, Meng
name: Huang, Jia
name: Wang, Jing
name: Zhang, Kun
name: Wang, Li
name: Zhou, Jiaojiao
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Virology
subject: Computational Biology

description: Circular RNAs (circRNAs) are novel noncoding RNAs with covalently closed-loop structures that can regulate eukaryotic gene expression. Due to their stable structure, circRNAs are widely distributed in the cytoplasm and have important biological functions, including as microRNA sponges, RNA-binding protein conjugates, transcription regulators, and translation templates. Breast cancer is among the most common malignant cancers diagnosed in women worldwide. Despite the development of comprehensive treatments, breast cancer still has high mortality rates. Recent studies have unmasked critical roles for circRNAs in breast cancer as regulators of tumour initiation, progression, and metastasis. Further, research has revealed that some circRNAs have the potential for use as diagnostic and prognostic biomarkers in clinical practice. Herein, we review the biogenesis and biological functions of circRNAs, as well as their roles in different breast cancer subtypes. Moreover, we provide a comprehensive summary of the clinical significance of circRNAs in breast cancer. CircRNAs are believed to be a hot focus in basic and clinical research of breast cancer, and innovative future research directions of circRNAs could be used as biomarkers, therapeutic targets, or novel drugs. Abbreviations: CeRNA: Competitive endogenous RNA; ciRNA: Circular intronic RNA; circRNA: Circular RNA; EIciRNA: Exon-intron circRNA; EMT: Epithelial–mesenchymal transition; IRES: Internal ribosome entry site; lncRNA: Long non-coding RNA; miRNA: MicroRNA; MRE: MiRNA response element; ncRNA: Non-coding RNA; RBP: RNA-binding protein; RNA-seq: RNA sequencing; RT-PCR: Reverse transcription-polymerase chain reaction
Regularity on abelian varieties II: basic results on linear series and defining equations
Creators: name: Pareschi, Giuseppe
name: Popa, Mihnea
Publisher: name: arXiv
Year: 2001
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14K05; 14K12

description: This paper is mainly concerned with applying the theory of M-regularity developed in the previous math.AG/0110003 to the study of linear series given by multiples of ample line bundles on abelian varieties. We define a new invariant of a line bundle, called M-regularity index, which is seen to govern the higher order properties and (partly conjecturally) the defining equations of such embeddings. We prove a general result on the behavior of higher syzygies in embeddings given by multiples of ample bundles whose base locus has no fixed components, extending a conjecture of Lazarsfeld known to be true by work of the first author. This approach also unifies essentially all the previously known results in this direction and is mainly based on vanishing theorems rather than representations of theta groups.
description: 22 pages; mistake in Example 3.7 and a few typos corrected; final version to appear in J. Algebraic Geom
МОДЕЛЬ ВИЗНАЧЕННЯ ВІДПОВІДНОСТІ ОБ’ЄКТА МІСТОБУДУВАННЯ МІСТОБУДІВНИМ ОБМЕЖЕННЯМ
Creators: name: Рибак Анатолій Іванович
name: Шахов Анатолій Валентинович
name: Азарова Ірина Борисівна
Publisher: name: figshare
Year: 2019
Subjects: subject: 120201 Building Construction Management and Project Planning
subject: FOS: Civil engineering

description: Розвиток населених пунктів України супроводжується рядом проблем, вирішення яких є основною задачею державного регулювання містобудівної діяльності. Проте цілий ряд нових функцій у містобудуванні за останніми змінами законодавства у галузі делегується новим учасникам, що не завжди є обізнаними професіоналами у містобудуванні. Сучасні інформаційні технології можуть зробити містобудівну діяльність простою та доступною для всіх нових її суб’єктів за допомогою розроблення спеціалізованого програмного забезпечення. Тому в рамках дослідження запропоновано модель визначення відповідності розміщення об’єкта містобудування діючим містобудівним обмеженням, на базі якої визначено програмні інструменти для розроблення спеціалізованого програмного забезпечення, що дасть змогу визначати відповідність між намірами використання земельної ділянки та наявними можливостями території з містобудівної точки зору, а також вирішити зворотне завдання ‒ обрати в межах міста оптимальні в містобудівному контексті земельні ділянки під провадження певного виду господарської діяльності. Результати дослідження можуть бути використані інвесторами, керівниками проектів та забудовниками для обґрунтування місця розміщення господарської діяльності при розробці інвестиційних ідей та бізнес-планів
Neutron background at Boulby mine
Creators: name: Kudryavtsev, V. A.
name: Lightfoot, P. K.
name: McMillan, J. E.
name: Robinson, M.
name: Spooner, N. J. C.
name: Smith, P. F.
name: Smith, N. J. T.
name: Lewin, J. D.
name: Luscher, R.
name: Liubarsky, I.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The neutron background at the underground laboratory at Boulby - a site for several dark matter experiments - is discussed. Special emphasis is put on the neutron background produced by cosmic-ray muons. The most recent versions of the muon propagation code MUSIC, and particle transport code FLUKA are used to evaluate muon and neutron fluxes. The results of simulations are compared with experimental data.
description: 6 pages, 6 figures, contribution to the IDM2002 Workshop
Additional file 10 of Independent evolution of the core and accessory gene sets in the genus Neisseria: insights gained from the genome of Neisseria lactamica isolate 020-06
Creators: name: Bennett, Julia S
name: Bentley, Stephen D
name: Vernikos, Georgios S
name: Quail, Michael A
name: Cherevach, Inna
name: White, Brian
name: Parkhill, Julian
name: Maiden, Martin CJ
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Authors’ original file for figure 1
ESTIMATING THE POTENTIAL ECONOMIC IMPACT OF PUCCINIA GRAMINIS F. SP. TRITICI TTKS RACE (UG99) (WHEAT STEM RUST)
Creators: name: Paarlberg, Philip
name: Seitzinger, Ann
name: Vo, Trang
name: Paarlberg, Philip
name: Seitzinger, Ann
name: Vo, Trang
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agricultural and Food Policy
subject: Crop Production/Industries
subject: Demand and Price Analysis
subject: International Relations/Trade
subject: Wheat Stem Rust
subject: Economic Impacts
subject: Trade

description: An agricultural sector model estimates impacts for hypothetical U.S. outbreaks of Ug99 wheat stem rust. Scenarios describe reductions in wheat output and exports beginning in 2013. The four year losses in the welfare of wheat producers range from $1.7- $11.6 billion (-15% to -107%). In scenarios reflecting alternate assumptions of disease spread, consumers benefit from embargoed crops remaining in the United States. The consumer surplus change varies between a gain of $4.6 billion (0.3%) when importing countries embargo U.S. wheat shipments and turn to other suppliers and a loss of $1.4 billion (-0.1%) when other countries continue importing the reduced supplies of U.S. wheat. Treatment costs are $139 million to $2.4 billion.
Characterization and Analysis of On-Chip Microwave Passive Components at Cryogenic Temperatures
Creators: name: Patra, Bishnu
name: Mehrpoo, Mohammadreza
name: Ruffino, Andrea
name: Sebastiano, Fabio
name: Charbon, Edoardo
name: Babaie, Masoud
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applied Physics (physics.app-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: This paper presents the characterization of microwave passive components, including metal-oxide-metal (MoM) capacitors, transformers, and resonators, at deep cryogenic temperature (4.2 K). The variations in capacitance, inductance and quality factor are explained in relation to the temperature dependence of the physical parameters and the resulting insights on modeling of passives at cryogenic temperatures are provided. Both characterization and modeling, reported for the first time down to 4.2 K, are essential in designing cryogenic CMOS radio-frequency integrated circuits, a promising candidate to build the electronic interface for scalable quantum computers.
Analisys of impact of remittance on poverty in Nigeria
Creators: name: Chukwuone, Nnaemeka
name: Amaechina, Ebele C.
name: Enebeli-Uzor, Sunday Emeka
name: Iyoko, Emelyn
name: Okpukpara, Benjamin
name: Chukwuone, Nnaemeka
name: Amaechina, Ebele C.
name: Enebeli-Uzor, Sunday Emeka
name: Iyoko, Emelyn
name: Okpukpara, Benjamin
Publisher: name: Unknown
Year: 2012
Subjects: subject: Public Economics
subject: Remittances
subject: Poverty
subject: Instrumental Variable
subject: Propensity Score Matching
subject: Nigeria

description: This study analyzes the impact of remittances on poverty in Nigeria, using data from the 2004 Nigerian National Living Standard Survey (NNLSS). The paper used a multinomial logit model with instrumental variables and the propensity score matching (PSM) method to estimate the impact of remittances on poverty. The use of these methods was based on two reasons. The first is to control for the problems of selectivity and endogeneity. The second is the fact that the implicit hypothesis of estimating the expenditures of the counterfactual group, as done in some previous studies, is in similarity between the group that receives remittances (treated) and the other that does not (untreated). The study finds that both internal and international remittances reduce the incidence, depth and severity of poverty. The statistical tests show a significant Average Treatment Effect on the Treated (ATT), due to internal and external remittances. The receipt of internal remittances reduces the poverty headcount by 11.14% and poverty gap by 9.7% while the receipt of international remittances makes poverty indices almost nil
IFOP Study of Public Opinion
Creators: name: Institut Francais D'Opinion Publique
Publisher: name: Roper Center for Public Opinion Research
Year: 2022

description: Voting in second round of 1969 presidential elections (8); most desirable politicians under Mr. Pompidou (1); opinion of Prime Minister Couve de Murville (3); voting in first round of 1969 presidential elections (1); voting in April 27th referendum (1); voting in legislative elections (1).
Topological phase induced by distinguishing parameter regimes in cavity optomechanical system with multiple mechanical resonators
Creators: name: Qi, Lu
name: Xing, Yan
name: Liu, Shutian
name: Zhang, Shou
name: Wang, Hong-Fu
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose two kinds of distinguishing parameter regimes to induce topological Su-Schrieffer-Heeger (SSH) phase in a one dimensional (1D) multi-resonator cavity optomechanical system via modulating the frequencies of both cavity fields and resonators. The introduction of the frequency modulations allows us to eliminate the Stokes heating process for the mapping of the tight-binding Hamiltonian without usual rotating wave approximation, which is totally different from the traditional mapping of the topological tight-binding model. We find that the tight-binding Hamiltonian can be mapped into a topological SSH phase via modifying the Bessel function originating from the frequency modulations of cavity fields and resonators, and the induced SSH phase is independent on the effective optomechanical coupling strength. On the other hand, the insensitivity of the system to the effective optomechanical coupling provides us another new path to induce the topological SSH phase based on the present 1D cavity optomechanical system. And we show that the system can exhibit a topological SSH phase via varying the effective optomechanical coupling strength in an alternative way, which is much more easier to be achieved in experiment. Furthermore, we also construct an analogous bosonic Kitaev model with the trivial topology by keeping the Stokes heating processes. Our scheme provides a steerable platform to investigate the effects of next-nearest-neighboring interactions on the topology of the system.
IFOP Study of Public Opinion
Creators: name: Institut Francais D'Opinion Publique
Publisher: name: Roper Center for Public Opinion Research
Year: 2022

description: Reactions to referendum results (2); voting in referendum (1); hearing about referendum results (1); beneficiaries of referendum (1); presidential candidates (3); the French Fifth Republic (1); role of the President (3); left-wing presidential candidate (1); French economy (2); voting in legislative elections (1).
Impact evaluation of the brazilian non-contibutory pension program Beneficio de Prestaçao Continuada (BPC) on family welfare
Creators: name: Kassouf, Ana Lucia
name: De Oliveira, Pedro Rodrigues
name: Kassouf, Ana Lucia
name: De Oliveira, Pedro Rodrigues
Publisher: name: Unknown
Year: 2012
Subjects: subject: Political Economy
subject: Public Economics
subject: impact evaluation
subject: regression discontinuity design
subject: cash transfer
subject: social assistance
subject: public policy
subject: labor supply
subject: child labor
subject: school attendance

description: The Benefício de Prestação Continuada (BPC) program is a non‐contributory pension addressed to poor elders over 65 years‐old. This paper evaluates its effects on household composition and on labor market outcomes of the elders and their co‐residing relatives. We could not capture any sign of changes in the household composition due to the program. However we found decreases in the labor force participation of the elders, indicating that the program makes it possible for these poor elders to retire, what would not be possible otherwise. Also there is a drop in labor force participation of co‐residents. However, the effect is heterogeneous and the effect is concentrated for adults over 30 years old, while there is no effect for young adults. When analyzing only rural areas, we observed a decrease in labor participation of elders and co‐residents from 18 to 50 years old receiving BPC. We also observe a decrease in child labor.
IFOP Study of Public Opinion
Creators: name: Institut Francais D'Opinion Publique
Publisher: name: Roper Center for Public Opinion Research
Year: 2022

description: April 10th talks between General de Gaulle and Michel Droit (1); April 27th voting (4); importance of regionalization and Senate reform (1); approval of General de Gaulle (1); de Gaulle's retirement (1); information on the April 27th referendum (2); Mr. Couve de Murville as Prime Minister (1); de Gaulle as President of the Republic (1); voting (2); opinion of French organizations and groups (1); economic situation (2); strikes (1); newspaper shops (1); science (4).
КЛАСИФІКАЦІЯ ЗНАНЬ ТА ІНСТРУМЕНТІВ ІНТЕГРАЦІЇ ДОДАТКІВ ПІДПРИЄМСТВА З МЕТОЮ ПОБУДОВИ ІНФОРМАЦІЙНОЇ СИСТЕМИ УПРАВЛІННЯ ПРОЕКТАМИ
Creators: name: Тулупов Михайло Олексійович
Publisher: name: figshare
Year: 2019
Subjects: subject: 120201 Building Construction Management and Project Planning
subject: FOS: Civil engineering

description: Забезпечення результативності, ефективності, керованості реалізації цілей та видів діяльності в умовах конкуренції потребує для їх підтримки застосування відповідних додатків, їх інтеграції в єдину інформаційну систему (ІС) для інтегрованого управління підприємством. ІС управління проектами (УП) є складовою єдиної ІС, будується для реалізації цілей інвестиційної діяльності. Для її побудови на практиці застосовують: модуль УП ERP, програмне забезпечення з УП, обидва додатки ізольовано або інтегровано. Доцільність інтеграції цих додатків пов'язана з: несумісністю їх інформаційних технологій; різною повнотою реалізації функціоналу УП та його відповідністю вимогам світових стандартів; наявністю зв'язку даних та видів діяльності в системі управління підприємством; неефективністю процесів УП через недоліки функціоналу УП ERP, ізольовану експлуатацію додатків та дублювання їх функцій і даних, ручне перенесення даних. Тому актуальним та своєчасним є застосування знань в галузі інтеграції додатків підприємства. Результатами дослідження є класифікації знань та інструментів у цій галузі. Класифікації пропонується застосовувати в проектах побудови ІС УП та в інших проектах інтеграції додатків підприємства.  
The stickiness phenomena of nonlocal minimal surfaces: new results and a comparison with the classical case
Creators: name: Bucur, Claudia
Publisher: name: arXiv
Year: 2019
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We discuss in this note the stickiness phenomena for nonlocal minimal surfaces. Classical minimal surfaces in convex domains do not stick to the boundary of the domain, hence examples of stickiness can be obtained only by removing the assumption of convexity. On the other hand, in the nonlocal framework, stickiness is "generic". We provide various examples from the literature, and focus on the case of complete stickiness in highly nonlocal regimes.
description: 27 pages, 7 figures
Impact de la crise économique mondiale de 2008-2009 sur l'économie sénégalaise
Creators: name: Cabral, François Joseph
name: Cabral, François Joseph
Publisher: name: Unknown
Year: 2012
Subjects: subject: International Development
subject: Public Economics
subject: aide publique au développement, transferts
subject: investissements directs étrangers
subject: impacts macroéconomiques
subject: modèle d’équilibre général calculable

description: Dans cette recherche, nous tentons d’évaluer les effets de la crise économique mondiale de 2008-2009 sur l’économie sénégalaise. A l’aide d’un modèle d’équilibre général calculable statique, nous mettons en exergue les principaux canaux par lesquels cette crise a pu se transmettre à l’économie, à savoir : les prix mondiaux, la demande à l’exportation, les transferts des migrants, l’aide publique au développement, les investissements directs étrangers. Les résultats de notre analyse attestent que la baisse de la demande mondiale à l’exportation et celle des transferts des migrants se révèlent être les canaux qui ont le plus facilité la transmission du choc à l’économie sénégalaise. En effet, celles-ci ont le plus contribué à déprimer l’activité économique et, en conséquence, favorisé une détérioration des principaux agrégats macroéconomiques. En outre, elles ont occasionné l’effritement de l’assiette fiscale de l’Etat qui a vu ses ressources intérieures baisser.
A translational repression reporter assay for the analysis of RNA-binding protein consensus sites
Creators: name: Nowacki, Jessica
name: Malenica, Mateo
name: Schmeing, Stefan
name: Schiller, Damian
name: Buchmuller, Benjamin
name: Amrahova, Gulshan
name: Hart, Peter ‘t
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: RNA-binding proteins are essential regulators of RNA processing and function. Translational repression assays can be used to study how they interact with specific RNA sequences by insertion of such a consensus sequence into the 5’ untranslated region of a reporter mRNA and measuring reporter protein translation. The straightforward set-up of these translational repression assays avoids the need for the isolation of the protein or the RNA providing speed, robustness and a low-cost method. Here, we report the optimization of the assay to function with linear RNA sequences instead of the previously reported hairpin type sequences to allow the study of a wider variety of RNA-binding proteins. Multiplication of a consensus sequence strongly improves the signal allowing analysis by both fluorescence intensity measurements and flow cytometry.
Microctenochira triplagiata
Creators: name: Sekerka, Lukáš
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Chrysomelidae
Microctenochira
Microctenochira triplagiata

description: * Microctenochira triplagiata (Spaeth, 1926)
(Fig. 4)
 Published record. São Paulo (SඉൺൾඍΗ 1926b).
 Type material examined. Hඈඅඈඍඒඉൾ (Fig. 4): pinned, ‘ SAÕ PAULO | BRAS. MRÁZ LGT. | MUS.PRAGENSE [w, p, cb, bf] || TYPUS [r, p, cb, bf] || Ctenochira | triplagiata m. [hw by F. Spaeth] | Spaeth det. | Typ. unic. [hw by F. Spaeth] [w, p, cb]’ (NMPC).
 Distribution. Brazil (São Paulo).
description: Published as part of Sekerka, Lukáš, 2020, Commented catalogue of Cassidinae (Coleoptera: Chrysomelidae) of the state of São Paulo, Brazil, with remarks on the collection of Jaro Mráz in the National Museum in Prague, pp. 667-707 in Acta Entomologica Musei Nationalis Pragae (Acta. Ent. Mus. Natl. Pragae) (Acta. Ent. Mus. Natl. Pragae) 60 (2) on page 677, DOI: 10.37520/aemnp.2020.048, http://zenodo.org/record/5178055
Tax reforms in Sri Lanka: will a tax on public servant improve progessivity?
Creators: name: Arunatilake, Nisha
name: Jayawardena, Priyanka
name: Wijesinha, Anushka
name: Arunatilake, Nisha
name: Jayawardena, Priyanka
name: Wijesinha, Anushka
Publisher: name: Unknown
Year: 2012
Subjects: subject: Public Economics
subject: comparing tax systems
subject: distributional effects of taxes
subject: income redistribution
subject: tax redistribution
subject: tax progressivity approach
subject: income progressivity approach
subject: tax revenue
subject: progressivity indices
subject: inequality effects of taxes

description: The Sri Lankan government implemented tax reforms in 2011, including removal of the tax exemption given to public servants and reduction of personal income tax rates in order to improve tax compliance from pay-as-you-earn (PAYE) tax payers. This study evaluates the 2007 and 2011 tax systems in order to examine the effects that taxing the income of public sector employees has on total tax revenues and the tax base. The study also compares the distributional effects of the different tax systems. Study further conducts simulation analyses to assess the most progressive means of achieving the 2007 tax revenue levels. Implications for tax evasion are also examined under different tax systems. The study finds that the 2011 tax reforms reduce tax revenue by 48 percent relative to the structure of income taxation in 2007. This decline in tax revenues occurs even though income taxes are extended to public sector workers because the 2011 tax reforms reduced the rate of income taxes across the board and increased the tax-free threshold. Our simulations show that tax revenues would have risen if the reforms were limited to introducing income taxes to public servants. The resulting (hypothetical) tax system would also have been more progressive than the tax structure resulting from the 2011 reforms. The study evaluated the distributional impacts of modifications to the 2011 tax system which would increase tax revenue to their level in 2007. More specifically, the present study finds that the most progressive way to attain this tax revenue target would be to increase tax rates on taxable income by 6 percentage points and to lower the tax-free threshold from LKR 600,000 to LKR 400,000.
Using stacks to impose tangency conditions on curves
Creators: name: Cadman, Charles
Publisher: name: arXiv
Year: 2003
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14A20

description: We define a Deligne-Mumford stack X_{D,r} which depends on a scheme X, an effective Cartier divisor D\subset X, and a positive integer r. Then we show that the Abramovich-Vistoli moduli stack of stable maps into X_{D,r} provides compactifications of the locally closed substacks of \bar{M}_{g,n}(X,β) corresponding to relative stable maps.
description: This paper has been withdrawn. It was accepted by the American Journal of Mathematics in revised form and can be downloaded from the author's webpage
The Growth and Distributive Impacts of Public Infrastructure Investments in the Philippines
Creators: name: Corong, Erwin
name: Dacuycuy, Lawrence
name: Reyes, Rachel
name: Taningco, Angelo
name: Corong, Erwin
name: Dacuycuy, Lawrence
name: Reyes, Rachel
name: Taningco, Angelo
Publisher: name: Unknown
Year: 2012
Subjects: subject: Public Economics
subject: Computable general equilibrium
subject: intertemporal choice and growth
subject: public infrastructure investment
subject: growth strategy
subject: microsimulation
subject: Philippines

description: This study investigates the role of public infrastructure investment on economic growth and poverty reduction in the Philippines. Using a dynamic general equilibrium-microsimulation model that explicitly models public capital as a production input, we find that the positive supply side effects of higher public investment expenditure manifest over time, through higher capital accumulation and improved productivity. Our findings reveal that higher public infrastructure investment not only positively impacts real GDP, but also reduces poverty and inequality in the short and long run. In this context, the Philippine government needs to become more proactive in finding ways to finance higher public investment expenditures. This is especially relevant with respect to international financing, given the narrow tax base in the country. Our simulation results confirm that international financing is a better alternative than tax financing when considered in terms of its ability to improve the economy’s physical infrastructure in order to create job opportunities, improve productivity and complement its social protection measures.
Impact of electron solvation on ice structures at the molecular scale
Creators: name: Bertram, Cord
name: Auburger, Philipp
name: Bockstedte, Michel
name: Stähler, Julia
name: Bovensiepen, Uwe
name: Morgenstern, Karina
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We determine the impact of electron solvation on D$_2$O structures adsorbed on Cu(111) with low temperature scanning tunneling microscopy, two-photon photoemission, and ab initio theory. UV photons generating solvated electrons lead not only to transient, but also to permanent structural changes through the rearrangement of individual molecules. The persistent changes occur near sites with a high density of dangling OH groups that facilitate electron solvation. We conclude that energy dissipation during solvation triggers permanent molecular rearrangement via vibrational excitation.
Brief 2 van 2019 Adviescommissie Limburgs Digitaal Erfgoed
Creators: name: Berg, Mijke Harst-Van Den
name: Helms, Remko
name: Helmus, Wilbert
name: Hermans, Martijn
name: Van De Leemput, Dirk
name: Van Meer, Marieke
name: Welters, Sandra
name: Wiggers, Lita
Publisher: name: Zenodo
Year: 2019
Subjects: Digitaal Erfgoed

description: De eerste adviesbrief van deze commissie is op 6 december 2018 aan het erfgoedveld gepresenteerd. Uit de reacties bleek dat het onderwerp digitaal erfgoed in Limburg leeft en dat de aanbevelingen uit de adviesbrief positief werden ontvangen en dat er een gemeenschappelijk streven lijkt te liggen. Zowel bij kleine musea en historische- en heemkundeverenigingen als bij professionele instellingen is grote behoefte aan gemeenschappelijke afspraken en aan toepasbare technologie. Resultaten van de Adviescommissie zijn bestemd voor Limburgse erfgoedorganisaties en -verenigingen, maar ook voor gemeenten en voor de Provincie. Deze tweede adviesbrief van 2019 is bedoeld als onderlegger van de eerste brief en geeft een aantal aanvullingen.
Management and motivation in Ugandan primary schools: an impact evaluation report
Creators: name: Barr, Abigail
name: Bategeka, Lawrence
name: Guloba, Madina
name: Kasirye, Ibrahim
name: Mugisha, Frederick
name: Serneels, Pieter
name: Zeitlin, Andrew
name: Barr, Abigail
name: Bategeka, Lawrence
name: Guloba, Madina
name: Kasirye, Ibrahim
name: Mugisha, Frederick
name: Serneels, Pieter
name: Zeitlin, Andrew
Publisher: name: Unknown
Year: 2012
Subjects: subject: Public Economics
subject: Uganda
subject: Universal primary education
subject: education services
subject: quality of education
subject: community-based monitoring
subject: accountability
subject: school management and motivation
subject: randomized controlled trial

description: Among the various challenges that the Ugandan government is facing to improve educational outcomes and achieve Universal Primary Education (UPE) in the country, is the necessity to improve the “quality of education”. Service delivery in education in Uganda has been proven to suffer, in great part, from the “weakness of accountability mechanisms between school administrators, teachers and the communities”. In order to assist national decision-makers in solving these issues, a team of local researchers set out to test and assess the effectiveness of two types of community-based monitoring interventions in improving general educational outcomes, using methods of randomized controlled trials (RCTs) on a sample of 100 rural public primary schools in the country. This paper presents the main findings from this experimental impact evaluation project.
A conserved HOTAIRM1-HOXA1 regulatory axis contributes early to neuronal differentiation
Creators: name: Segal, Dana
name: Coulombe, Samy
name: Sim, Jasper
name: Dostie, Josée
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Computational Biology

description: HOTAIRM1 is unlike most long non-coding RNAs in that its sequence is highly conserved across mammals. Such evolutionary conservation points to it having a role in key cellular processes. We previously reported that HOTAIRM1 is required to curb premature activation of downstream HOXA genes in a cell model recapitulating their sequential induction during development. We found that it regulates 3’ HOXA gene expression by a mechanism involving epigenetic and three-dimensional chromatin changes. Here we show that HOTAIRM1 participates in proper progression through the early stages of neuronal differentiation. We found that it can associate with the HOXA1 transcription factor and contributes to its downstream transcriptional program. Particularly, HOTAIRM1 affects the NANOG/POU5F1/SOX2 core pluripotency network maintaining an undifferentiated cell state. HOXA1 depletion similarly perturbed expression of these pluripotent factors, suggesting that HOTAIRM1 is a modulator of this transcription factor pathway. Also, given that binding of HOTAIRM1 to HOXA1 was observed in different cell types and species, our results point to this ribonucleoprotein complex as an integral part of a conserved HOTAIRM1-HOXA1 regulatory axis modulating the transition from a pluripotent to a differentiated neuronal state.
Securing Students For Learning Effectiveness: The Closed-Circuit Television Angle
Creators: name: Ogunmodede, Aderemi
name: Adeoluwa, Prof O. V.
name: Opeyemi, Ajayi
Publisher: name: figshare
Year: 2022
Subjects: subject: 130306 Educational Technology and Computing
subject: FOS: Educational sciences

description: The study examined teaching and learning effectiveness with the use of close circuit television andprevention of increased rate of crime in secondary schools in Ekiti State.The finding revealed that using CCTV in secondary schools willsignificantly reduce the crime rate in public secondary schools in Ekiti, the result revealed that theuse of CCTV in the classroom will significantly enhance teaching methodology and improve learningeffectiveness. The finding also revealed that the use of CCTV in secondary schools will combat anycrime in the school community.
Additional file 11 of Independent evolution of the core and accessory gene sets in the genus Neisseria: insights gained from the genome of Neisseria lactamica isolate 020-06
Creators: name: Bennett, Julia S
name: Bentley, Stephen D
name: Vernikos, Georgios S
name: Quail, Michael A
name: Cherevach, Inna
name: White, Brian
name: Parkhill, Julian
name: Maiden, Martin CJ
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Authors’ original file for figure 2
Determination of Factors Driving Risk Premiums in Forward Contracts for Kansas Wheat
Creators: name: Taylor, Mykel
name: Tonsor, Glynn
name: Taylor, Mykel
name: Tonsor, Glynn
Publisher: name: Unknown
Year: 2013
Subjects: Agricultural marketing

description: Forward contracts are a risk management tool used by farmers to eliminate adverse price and basis movements prior to harvest. Elevators offering these forward contracts will offset their risk exposure by hedging their position in the futures market. However, the elevators are still exposed to basis risk and will, in turn, charge a premium to the farmers as compensation. Since 2007, basis volatility for hard red wheat in Kansas has increased, causing greater risk exposure for elevators offering forward contracts. The result has been an increase in average risk premiums of $0.06 to $0.10 per bushel. The primary factors driving this increase in the risk premium are basis and futures volatility, basis forecasting errors by elevators, and elevator- and time-specific fixed effects. The impact of this study is an increase in information for farmers on the relative costs of decreasing their basis risk exposure in a more volatile market.
A Continuous Model of Computation
Creators: name: Traub, J. F.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Numerical Analysis (math.NA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Although the Turing-machine model of computation is widely used in computer science it is fundamentally inadequate as a foundation for the theory of modern scientific computation. The real-number model is described as an alternative. Physicists often choose continuous mathematical models for problems ranging from the dynamical systems of classical physics to the operator equations and path integrals of quantum mechanics.These mathematical models use the real or complex number fields and we argue that the real-number model of computation should be used in the study of the computational complexity of continuous mathematical models. The study of continuous complexity is called information-based complexity. In this expository article we apply information-based complexity to topics such as breaking the curse of dimensionality, approximating the calculation of path integrals, and solving ill-posed problems. Precise formulations of these ideas may be found in J. F. Traub and A. G. Werschulz, "Complexity and Information", Cambridge University Press, 1998.
description: 13 pages
Additional file 1 of Thrombospondin-2 acts as a bridge between tumor extracellular matrix and immune infiltration in pancreatic and stomach adenocarcinomas: an integrative pan-cancer analysis
Creators: name: Liao, Xingchen
name: Wang, Wei
name: Yu, Baoping
name: Tan, Shiyun
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 1. Orignial Images for Western blot
Have Extended Trading Hours Made Agricultural Commodity Markets More Risky?
Creators: name: Kauffman, Nathan S.
name: Kauffman, Nathan S.
Publisher: name: Unknown
Year: 2013
Subjects: Agricultural marketing

description: In May 2012, the Chicago Mercantile Exchange extended trading hours for several agricultural commodities, including corn. Since then, trading during the release of a key U.S. Department of Agriculture report known as the World Agricultural Supply and Demand Estimate has been possible. Some concerns have been expressed that trading through the release of important market information might generate higher price volatility in agricultural commodity markets. The purpose of this paper is to examine the effect of extended trading hours on intraday price volatility in corn futures markets. The results suggest that trading during the information releases in 2012 has led to brief periods of excessive volatility immediately after the reports were released, but the higher volatility did not persist much beyond 60 minutes. The paper also highlights the role of higher liquidity in absorbing potential market shocks.
Additional file 12 of Independent evolution of the core and accessory gene sets in the genus Neisseria: insights gained from the genome of Neisseria lactamica isolate 020-06
Creators: name: Bennett, Julia S
name: Bentley, Stephen D
name: Vernikos, Georgios S
name: Quail, Michael A
name: Cherevach, Inna
name: White, Brian
name: Parkhill, Julian
name: Maiden, Martin CJ
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Authors’ original file for figure 3
From racks to pointed Hopf algebras
Creators: name: Andruskiewitsch, Nicolas
name: Graña, Matias
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 16W30

description: A fundamental step in the classification of finite-dimensional complex pointed Hopf algebras is the determination of all finite-dimensional Nichols algebras of braided vector spaces arising from groups. The most important class of braided vector spaces arising from groups is the class of braided vector spaces (CX, c^q), where C is the field of complex numbers, X is a rack and q is a 2-cocycle on X with values in C^*. Racks and cohomology of racks appeared also in the work of topologists. This leads us to the study of the structure of racks, their cohomology groups and the corresponding Nichols algebras. We will show advances in these three directions. We classify simple racks in group-theoretical terms; we describe projections of racks in terms of general cocycles; we introduce a general cohomology theory of racks contaninig properly the existing ones. We introduce a "Fourier transform" on racks of certain type; finally, we compute some new examples of finite-dimensional Nichols algebras.
description: 54 pages. Several minor corrections. Some references added. Same version as will appear in Adv. Math
A full repertoire of Hemiptera genomes reveals a multi-step evolutionary trajectory of auto-RNA editing site in insect Adar gene
Creators: name: Ma, Ling
name: Zheng, Caiqing
name: Xu, Shiwen
name: Xu, Ye
name: Song, Fan
name: Tian, Li
name: Cai, Wanzhi
name: Li, Hu
name: Duan, Yuange
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Adenosine-to-inosine (A-to-I) RNA editing, mediated by metazoan ADAR enzymes, is a prevalent post-transcriptional modification that diversifies the proteome and promotes adaptive evolution of organisms. The Drosophila Adar gene has an auto-recoding site (termed S>G site) that forms a negative-feedback loop and stabilizes the global editing activity. However, the evolutionary trajectory of Adar S>G site in many other insects remains largely unknown, preventing us from a deeper understanding on the significance of this auto-editing mechanism. In this study, we retrieved the well-annotated genomes of 375 arthropod species including the five major insect orders (Lepidoptera, Diptera, Coleoptera, Hymenoptera and Hemiptera) and several outgroup species. We performed comparative genomic analysis on the Adar auto-recoding S>G site. We found that the ancestral state of insect S>G site was an uneditable serine codon (unSer) and that this state was largely maintained in Hymenoptera. The editable serine codon (edSer) appeared in the common ancestor of Lepidoptera, Diptera and Coleoptera and was almost fixed in the three orders. Interestingly, Hemiptera species possessed comparable numbers of unSer and edSer codons, and a few ‘intermediate codons’, demonstrating a multi-step evolutionary trace from unSer-to-edSer with non-synchronized mutations at three codon positions. We argue that the evolution of Adar S>G site is the best genomic evidence supporting the ‘proteomic diversifying hypothesis’ of RNA editing. Our work deepens our understanding on the evolutionary significance of Adar auto-recoding site which stabilizes the global editing activity and controls transcriptomic diversity.
Endonucleolytic processing plays a critical role in the maturation of ribosomal RNA in Methanococcus maripaludis
Creators: name: Qi, Lei
name: Liu, Huan
name: Gao, Jian
name: Deng, Kai
name: Wang, Xiaoyan
name: Dong, Xiuzhu
name: Li, Jie
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Virology

description: Ribosomal RNA (rRNA) processing and maturation are fundamentally important for ribosome biogenesis, but the mechanisms in archaea, the third form of life, remains largely elusive. This study aimed to investigate the rRNA maturation process in Methanococcus maripaludis, a representative archaeon lacking known 3′-5′ exonucleases. Through cleavage site identification and enzymatic assays, the splicing endonuclease EndA was determined to process the bulge-helix-bulge (BHB) motifs in 16S and 23S rRNA precursors. After splicing, the circular processing intermediates were formed and this was confirmed by quantitative RT-PCR and Northern blot. Ribonuclease assay revealed a specific cleavage at a 10-nt A/U-rich motif at the mature 5′ end of pre-16S rRNA, which linearized circular pre-16S rRNA intermediate. Further 3′-RACE and ribonuclease assays determined that the endonuclease Nob1 cleaved the 3′ extension of pre-16S rRNA, and so generated the mature 3′ end. Circularized RT-PCR (cRT-PCR) and 5′-RACE identified two cleavage sites near helix 1 at the 5′ end of 23S rRNA, indicating that an RNA structure-based endonucleolytic processing linearized the circular pre-23S rRNA intermediate. In the maturation of pre-5S rRNA, multiple endonucleolytic processing sites were determined at the 10-nt A/U-rich motif in the leader and trailer sequence. This study demonstrates that endonucleolytic processing, particularly at the 10-nt A/U-rich motifs play an essential role in the pre-rRNA maturation of M. maripaludis, indicating diverse pathways of rRNA maturation in archaeal species.
Octotoma brasiliensis Weise 1921
Creators: name: Sekerka, Lukáš
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Chrysomelidae
Octotoma
Octotoma brasiliensis

description: * Octotoma brasiliensis Weise, 1921
 New record. BRAZIL: Sඞඈ Pൺඎඅඈ: without further data, 4 spec., J. Mráz leg. (NMPC, 1 LSPC).
 Distribution. Brazil. New to São Paulo.
 Remarks. The species was so far known only from the type material labelled generally Brazil.
description: Published as part of Sekerka, Lukáš, 2020, Commented catalogue of Cassidinae (Coleoptera: Chrysomelidae) of the state of São Paulo, Brazil, with remarks on the collection of Jaro Mráz in the National Museum in Prague, pp. 667-707 in Acta Entomologica Musei Nationalis Pragae (Acta. Ent. Mus. Natl. Pragae) (Acta. Ent. Mus. Natl. Pragae) 60 (2) on page 681, DOI: 10.37520/aemnp.2020.048, http://zenodo.org/record/5178055
МЕТОДИ ДОСЛІДЖЕННЯ МЕРЕЖІ ЗВ’ЯЗКІВ ПРИ РЕАЛІЗАЦІЇ ПРОЕКТУ
Creators: name: Трач Роман Володимирович
Publisher: name: figshare
Year: 2019
Subjects: subject: 120201 Building Construction Management and Project Planning
subject: FOS: Civil engineering

description: Очевидним є той факт, що сучасні проекти (у т.ч. і у будівництві) стають дедалі складнішими, що вимагає залучення досить значної кількості учасників. Отже, збільшення кількості учасників проекту призводить до ускладнення комунікацій при передачі знань та інформації, що досить часто є причиною збільшення тривалості реалізації проекту та зростання незапланованих витрат. Отже, постає проблема з ідентифікацією, вимірюванням, контролем та управлінням зв’язками всередині проекту. Інструментом для вирішення завдань, пов’язаних з дослідженням і оптимізацією внутрішньопроектних мереж є аналіз соціальних мереж (анлг. Social Network Analysis, SNA). Аналіз соціальних мереж активно застосовуєтьсядля дослідження організаційних комунікацій, у т. ч. і в контексті управління сучасними організаційними структурами. Однак щодо управління та оптимізації управління проектом в будівництві аналіз соціальної мережі практично не застосовувався. Детально розглянуто методи дослідження мереж та основні міри центральності для мережі (графа) та учасників проекту (вершин графа).
How Much Would It Be Worth to Know the WASDE Report In Advance?
Creators: name: Milacek, Trent T.
name: Brorsen, B. Wade
name: Milacek, Trent T.
name: Brorsen, B. Wade
Publisher: name: Unknown
Year: 2013
Subjects: Agricultural marketing

description: Past research has shown that prices move in response to WASDE reports, but have only looked at price movements right before and right after the reports. This research seeks to determine the profitability of trading based on knowing the next WASDE report at the time of the current report. The research should help traders evaluate investments in efforts to predict the report. First, a trade and hold model is used to determine the profits of trading based on whether ending stocks will be up or down in the next WASDE report. Second, a price forecast model using an ending stocks regression is used to forecast price at the next WASDE report release. The intercept of the model is calibrated so that the model predicts the current price without error; the slope is based on report data from no more than the last two years of data. Using the forecasted price, the position of the trading model’s profit calculation can change daily based on where the closing price of the commodity is in relation to the price prediction. Profits were averaged on a days-til-report, monthly, and yearly basis. Both models were profitable and the most profitable day to trade was the report release day. However, the trade and hold model outperformed the variable position model which suggests more work is needed to increase the forecasting power of this model. This might be accomplished by using additional years of data or by a form of Bayesian smoothing to improve the forecasts.