cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
SnO2-SiO2 1D Core-Shell Nanowires Heterostructures for Selective Hydrogen Sensing
Creators: name: Raza, Muhammad Hamid
name: Kaur, Navpreet
name: Comini, Elisabetta
name: Pinna, Nicola
Publisher: name: Humboldt-Universität zu Berlin
Year: 2021
Subjects: subject: atomic layer deposition
subject: core-shell nanowires
subject: H2selectivity
subject: shell thickness
subject: SnO2-SiO2
subject: 540 Chemie und zugeordnete Wissenschaften

description: SnO2 is one of the most employed n-type semiconducting metal oxide in chemo-resistive gas-sensing although it presents serious limitations due to a low selectivity. Herein, the authors introduce 1D SnO2-SiO2 core-shell nanowires (CSNWs). The amorphous SiO2-shell layer with varying thicknesses (1.8–10.5 nm) is grown onto the SnO2 nanowires (NWs) by atomic layer deposition (ALD). SiO2-coated SnO2 CSNWs show a dramatic improvement of the selectivity towards hydrogen. Moreover, the sensing-response is strongly correlated to the thickness of the SiO2-shell and the working temperature. The SnO2-SiO2 CSNWs sensor with a 4.8-nm SiO2 shell thickness exhibits the best selectivity and sensitivity, having ca. 7-fold higher response toward hydrogen compared to bare-SnO2 NWs. The selectivity and enhanced sensing-response are related to the masking effect of the SiO2 shell and an increase in the width of the electron-depletion-layer due to a strong electronic coupling between the SnO2 core and SiO2 coating, respectively.
Using item response theory to enrich and expand the PROMIS ® pediatric self report banks
Creators: name: Liu, Yang
name: Quinn, Hally
name: Magnus, Brooke
name: DeWalt, Darren A
name: Gross, Heather E
name: Thissen, David
Publisher: name: BioMed Central Ltd
Year: 2014

description: Abstract Background The primary objective was to enhance the content coverage of some of the pediatric self-report item banks for ages 8–17 years from the National Institutes of Health (NIH) Patient Reported Outcomes Measurement Information System (PROMIS®), and extend the range of precise measurement to higher levels of physical functioning. Methods Data from 1,419 pediatric patients with cancer, chronic kidney disease, obesity, rehabilitation needs, rheumatic disease, and sickle cell disease were combined with item responses from the original standardization sample of 3,048 children to calibrate new items for the pediatric PROMIS Anger, Anxiety, Depressive Symptoms, Pain Interference, Fatigue, and physical functioning Upper Extremity and Mobility scales. Simultaneous or concurrent calibration using the graded item response theory model placed all of the items on the same scale. Results Twenty-two of 28 potential new items were added across the seven scales. A recommended short form was proposed for the Anger scale, and the recommended short forms for the Anxiety and Depressive Symptoms scales were revised. Unfortunately, we were not particularly successful at extending the range of measurement for the physical functioning banks. Conclusions The present study expanded PROMIS pediatric item banks to add new content and to increase the range of measurement. Using item response theory, the banks were revised and expanded without changing the underlying scale of measurement. For Anger, Anxiety, and Depressive Symptoms, we successfully added new content that may render those banks more robust and flexible.
Microdeletion of 6q16.1 encompassing EPHA7 in a child with mild neurological abnormalities and dysmorphic features: a case report
Creators: name: Fan, Zheng
name: Hudson, Beth
Publisher: name: BioMed Central Ltd
Year: 2009

description: Abstract Background Of the fewer than 100 cases reported within the literature of constitutional deletions involving the long arm of chromosome 6, only five have been characterized using high-resolution microarray analysis. Reported 6q deletion patients show a high incidence of mental retardation, ear anomalies, hypotonia, and postnatal growth retardation. Results We report a 16-month-old male presenting with developmental delay and dysmorphic features who was found by array-based comparative genomic hybridization (aCGH) to have a ~2.16 Mb de novo deletion within chromosome band 6q16.1 that encompasses only two genes. Expression studies of the mouse homologue of one of the genes, the ephrin receptor 7 gene (EPHA7), have shown the gene functions during murine embryogenesis to form cortical domains, determine brain size and shape, and play a role in development of the central nervous system (CNS). Discussion Our results suggest that deletion of EPHA7 plays a role in the neurologic and dysmorphic features, including developmental delay, hypotonia, and ear malformations, observed in some 6q deletion patients.
Mixotrophic cultivation enhances lipid productivity and fatty acid profile towards efficient production of microalgae-based biofuel from Desmodesmus sp. DLK
Creators: name: Shah, Shivangi
name: Sahoo, Dinabandhu
name: Mishra, Girish
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Inorganic Chemistry

description: The selection of an appropriate strain is important for the sustainability of algae-based oil industries. In the current study, a novel omega-3 fatty acid-rich microalgal strain was isolated and identified as Desmodesmus sp. Dal Lake Kashmir (DLK) based on its morphology and molecular characterization. Its potential as biofuel feedstock was established based on its appropriate fatty acid profile and enhanced lipid productivity. The growth of Desmodesmus sp. DLK was evaluated using varying concentrations of three exogenous carbon sources (glucose, glycerol and sodium acetate) to examine the potential of the freshwater microalga to ameliorate biomass and lipid production for proficient biofuel production. A phenomenal enhancement in biomass productivity (12.8-fold) and lipid productivity (22-fold) was detected with 1% glucose in comparison to control. Supplementation with glycerol boosted the productivity of biomass and lipid maximum by 11.4-fold (5 g.L−1 gly) and 26.8-fold (10 g.L−1 gly), respectively. Analyses of fatty acid methyl esters from mixotrophically grown culture, via gas chromatography and mass spectrometry, exhibited a prevalence of palmitic acid (C16:0; 37%) and oleic acid (C18:1; 53%) demonstrating desirable properties for biofuel quality. This study highlights that the mixotrophic cultivation of Desmodesmus sp. DLK redirects algal metabolite fluxes towards the production of improved lipids, suitable for biofuel production.
CALET's Sensitivity to Dark Matter Annihilation in the Galactic Halo
Creators: name: Motz, Holger
name: Asaoka, Yoichi
name: Torii, Shoji
name: Bhattacharyya, Saptashwa
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: CALET (Calorimetric Electron Telescope), installed on the ISS in August 2015, directly measures the electron+positron cosmic rays flux up to 20 TeV. With its proton rejection capability of 1:10^5 and an aperture of 1200 cm^2 sr, it will provide good statistics even well above one TeV, while also featuring an energy resolution of 2%, which allows it to detect fine structures in the spectrum. Such structures may originate from Dark Matter annihilation or decay, making indirect Dark Matter search one of CALET's main science objectives among others such as identification of signatures from nearby supernova remnants, study of the heavy nuclei spectra and gamma astronomy. The latest results from AMS-02 on positron fraction and total electron+positron flux can be fitted with a parametrization including a single pulsar as an extra power law source with exponential cut-off, which emits an equal amount of electrons and positrons. This single pulsar scenario for the positron excess is extrapolated into the TeV region and the expected CALET data for this case are simulated. Based on this prediction for CALET data, the sensitivity of CALET to Dark Matter annihilation in the galactic halo has been calculated. It is shown that CALET could significantly improve the limits compared to current data, especially for those Dark Matter candidates that feature a large fraction of annihilation directly into electron+positron, such as the LKP (Lightest Kaluza-Klein Particle).
description: 13 pages, 8 figures
title: Cardiac pacemaker and implantable cardio-defibrillator: systematic reading
Creators: name: Alandete, Salvador Pascual
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Thorax
subject: Cardiac
subject: Cardiovascular system
subject: Conventional radiography
subject: Ultrasound-Colour Doppler
subject: CT
subject: Education
subject: eLearning
subject: Complications
subject: Prostheses
subject: Education and training
subject: Foreign bodies

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Do radiologists know what to evaluate when reporting on a cardiac device in a chest X-ray? In this study, we try to do a systematic review in the different types of pacemakers and implantable cardio-defibrillators (ICD). We also revise their usual...
APTrust DuraSpace Wiki
Publisher: name: University of Virginia
Year: 2012
Subjects: aptrust
duraspace wiki

description: This archive represents the complete copy of the first Academic Preservation Trust wiki from 2014. The content covers initial implementation details of the APTrust Repository on April 2013. It also covers meeting minutes amongst other notes. It comprises one of the earliest documented work of the APTrust repository. 

The WARC file of the entire wiki was crawled on May 15th 2018 6pm. InternetArchive's Brozzler tool was used to create the crawl. https://github.com/internetarchive/brozzler

In addition to the WARC file this item includes a PDF export. A functionality the JIRA wiki provides which the wiki was hosted on. The PDF export was taken on 2017-02-09 1:46pm

A browsable version of the website is accessible here: https://webrecorder.io/lw2cd/apt_duraspacewiki
That version has been created on 2/28/2017, 9:35:11 PM
APTrust Member-Wiki
Publisher: name: University of Virginia
Year: 2016
Subjects: APTrust
Academic Preservation Trust

description: This archive contains a webcrawl of the APtrust member-wiki that was first published on Thu Mar 24 2016 08:58:52 GMT-0400 (EDT). It provided documentation and working group content until Aug 31, 2017. The member-wiki was replaced by a new version after that date. Content was largely migrated to https://wiki.apturst.org and restructured with an updated information architecture. 

This item includes two files:
- A web crawl that was created on May 9th 6:36pm by using InternetArchives Brozzler (https://github.com/internetarchive/brozzler)
- An Google Sites export of files
title: Can age be an independent prognostic factor for overall survival and recurrence-free survival after transarterial chemoembolization in hepatocellular carcinoma patients? A retrospective observational study
Creators: name: Ascanio, Salvatore
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Geriatrics
subject: Cancer
subject: Arterial access
subject: Catheter arteriography
subject: Oncology
subject: Liver
subject: Interventional vascular

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of the present study is to assess how age can be an independent prognostic factor for overall survival and for recurrence-free survival in patients treated with transarterial chemoembolization...
The evolution of data sharing practices in the psychological literature
Creators: name: Neve, Judith
name: Rousselet, Guillaume
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: data sharing
subject: data sharing rates
subject: meta psychology
subject: meta science
subject: open science

description: This is a frozen registration of the project after having submitted it to Meta-Psychology and done the first round of revisions.
title: Deepen your understanding time enhancement curve of various injection method
Creators: name: Sasaki, Tsukasa
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Education and training
subject: Contrast agent-intravenous
subject: CT-Angiography
subject: Contrast agents

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To determine Time Enhancement Curve (TEC) affects while varying the contrast medium delivery...
A randomized controlled trial of directive and nondirective smoking cessation coaching through an employee quitline
Creators: name: Fischer, Irene
name: Highstein, Gabrielle R.
name: Sumner, Walton, II
name: McQueen, Amy
name: Yan, Yan
name: Fisher, Edwin
name: Walker, Mark S.
Publisher: name: BioMed Central
Year: 2016

description: Abstract Background Telephone quitlines can help employees quit smoking. Quitlines typically use directive coaching, but nondirective, flexible coaching is an alternative. Call-2-Quit used a worksite-sponsored quitline to compare directive and nondirective coaching modes, and evaluated employee race and income as potential moderators. Methods An unblinded randomized controlled trial compared directive and nondirective telephone coaching by trained laypersons. Participants were smoking employees and spouses recruited through workplace smoking cessation campaigns in a hospital system and affiliated medical school. Coaches were four non-medical women trained to use both coaching modes. Participants were randomized by family to coaching mode. Participants received up to 7 calls from coaches who used computer assisted telephone interview software to track topics and time. Outcomes were reported smoking abstinence for 7 days at last contact, 6 or 12 months after coaching began. Both worksites implemented new tobacco control policies during the study. Results Most participants responded to an insurance incentive introduced at the hospital. Call-2-Quit coached 518 participants: 22 % were African-American; 45 % had incomes below $30,000. Income, race, and intervention did not affect coaching completion rates. Cessation rates were comparable with directive and nondirective coaching (26 % versus 30 % quit, NS). A full factorial logistic regression model identified above median income (odds ratio = 1.8, p = 0.02), especially among African Americans (p = 0.04), and recent quit attempts (OR = 1.6, p = 0.03) as predictors of cessation. Nondirective coaching was associated with high cessation rates among subgroups of smokers reporting income above the median, recent quit attempts, or use of alternative therapies. Waiting up to 4 weeks to start coaching did not affect cessation. Of 41 highly addicted or depressed smokers who had never quit more than 30 days, none quit. Conclusion Nondirective coaching improved cessation rates for selected smoking employees, but less expensive directive coaching helped most smokers equally well, regardless of enrollment incentives and delays in receiving coaching. Some subgroups had very low cessation rates with either mode of quitline support. Trial registration ClinicalTrials.gov NCT02730260 , Registered March 31, 2016
Rare Decays Probing Physics Beyond the Standard Theory
Creators: name: Teubert, Frederic
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the last 50 years we have seen how an initially ad-hoc and not widely accepted theory of the strong and electroweak interactions (Standard Theory: ST) has correctly predicted the entire accelerator based experimental observations with incredible accuracy (with the important exception of neutrino oscillation experiments). Decays of the ST particles (quarks and leptons), which are rare due to some symmetry of the theory, have played an important role in the formalism of the ST. These rare decays have been powerful tools to search for new particle interactions with the ST particles, which may not necessarily have the same symmetries. In this article, I will describe the indirect search for evidence of new physics (NP) using quark and lepton flavour changing neutral decays, which are highly suppressed within the ST, and constitute strong probes of potential new flavour structures.
description: A contribution to: The Standard Theory up to the Higgs discovery - 60 years of CERN, L. Maiani and G. Rolandi, eds
APTrust Operations Wiki
Publisher: name: University of Virginia
Year: 2018

description: This wiki was primarily used for internal technical documentation that wasn't for public consumption like server or application configuration.  For overall technical documentation and architecture see the publicly available APTrust Wiki.

Sensitive information is not relevant anymore since the system has been updated and access credentials changed. 

This item includes one files:
- A web crawl that was created on Sept 29th 2018 by using InternetArchives Brozzler (https://github.com/internetarchive/brozzler)
Searching for Optical Counterparts to Ultra-compact High Velocity Clouds: Possible Detection of a Counterpart to AGC 198606
Creators: name: Janesh, William
name: Rhode, Katherine L.
name: Salzer, John J.
name: Janowiecki, Steven
name: Adams, Elizabeth A. K.
name: Haynes, Martha P.
name: Giovanelli, Riccardo
name: Cannon, John M.
name: Muñoz, Ricardo R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report on initial results from a campaign to obtain optical imaging of a sample of Ultra Compact High Velocity Clouds (UCHVCs) discovered by the ALFALFA neutral hydrogen (HI) survey. UCHVCs are sources with velocities and sizes consistent with their being low-mass dwarf galaxies in the Local Volume, but without optical counterparts in existing catalogs. We are using the WIYN 3.5-m telescope and pODI camera to image these objects and search for an associated stellar population. In this paper, we present our observational strategy and method for searching for resolved stellar counterparts to the UCHVCs. We combine careful photometric measurements, a color-magnitude filter, and spatial smoothing techniques to search for stellar overdensities in the g- and i-band images. We also run statistical tests to quantify the likelihood that whatever overdensities we find are real and not chance superpositions of sources. We demonstrate the method by applying it to two data sets: WIYN imaging of Leo P, a UCHVC discovered by ALFALFA and subsequently shown to be a low-mass star-forming dwarf galaxy in the Local Volume, and WIYN imaging of AGC198606, an HI cloud identified by ALFALFA that is near in position and velocity to the Local Group dwarf Leo T. Applying the search method to the Leo P data yields an unambiguous detection (>99% confidence) of the galaxy's stellar population. Applying our method to the AGC198606 imaging yields a possible detection (92% confidence) of an optical counterpart located ~2.5 arc minutes away from the centroid of AGC198606's HI distribution and within the HI disk. We use the optical data to estimate a distance to the stellar counterpart between 373 and 393 kpc, with an absolute magnitude M_i = -4.67+/-0.09. Combining the WIYN data with our previous estimate of the HI mass of AGC198606 from WSRT imaging yields an HI-to-stellar mass ratio of ~45-110.
description: 13 pages, 8 figures; accepted to ApJ
title: MR imaging-guided vacuum-assisted breast biopsy for the interventionalist
Creators: name: De Falco Alfano, Daniele
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Breast
subject: MR
subject: Biopsy
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of our study was to evaluate the accuracy of the procedure VABB with probe needles 11 G under MRI guidance in the characterization of non-palpable breast lesions visible only on dynamic...
title: MR Imaging of Ankle Anatomy and Review of Common Ankle Pathologies
Creators: name: Flaherty, Erin
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Trauma
subject: eLearning
subject: MR
subject: Musculoskeletal joint

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The purpose of this pictoral essay is to: Familiarize the audience withnormal ankle anatomy as it appears on MRI Aid in the interpretation and diagnosis ofcommon ankle pathologies, including osseous, tendinous, and ligamentous injuries, as well as...
Lokale Netzwerke stärken und die Agar- und Ernährungswende endlich vorantreiben – wie das gelingen könnte?!
Creators: name: v. Münchhausen, Susanne
Publisher: name: Zenodo
Year: 2023
Subjects: Network
Coinnovation
Giessen
Hessen
Food Council
Ernährungsrat

description: The aim of the presentation was to show why our work in local networks such as food councils is important, why it follows an overarching logic and why it makes sense. Only time will tell whether our voluntary and full-time commitment will ultimately succeed in making a significant contribution to climate protection, biodiversity conservation, food security and individual food choices. The purpose of the presentation was to shed some light on the complexity of the challenges associated with the much-needed transformation of the agri-food system. The presentation highlights the role of co-innovation based on the lessons learned from the LIAISON project. The conclusion focused on the importance of involving local food initiatives such as the Giessen Food Council, which was the organiser of the event at the Town Hall on 20 January 2023.
description: Der Vortrag war Einführung in die Abendveranstaltung "Unsere Ernährung neu gestalten - besser heute als morgen. Was in Gießen zum Thema Ernährungswende passiert, wer sich für ein nachhaltiges Ernährungssystem einsetzt und wer dies bereits lebt. Und wer mitmachen möchte..."
title: Comment aider les élèves à secondariser les enjeux de la démarche scientifique et éviter la simple exécution de tâches successives ?
title: Comment aider les élèves à secondariser les enjeux de la démarche scientifique et éviter la simple exécution de tâches successives ?
titleType: AlternativeTitle
Creators: name: Lanz, Jennifer
name: Linder, Clara
Publisher: name: Unknown
Year: 0
Subjects: subject: démarche scientifique
subject: secondarisation
subject: évaluation formative dynamique
subject: choix didactiques
subject: régulation
subject: compréhension

description: La démarche scientifique a une place importante dans l’enseignement des sciences. Il est primordial que les élèves comprennent que lorsque nous faisons des sciences, nous ne sommes pas dans la simple exécution de tâches, mais bien dans un processus qui est celui de la démarche scientifique. Dans ce travail de mémoire, nous nous sommes donc posé la question suivante : « Comment aider les élèves à secondariser les enjeux de la démarche scientifique et éviter la simple exécution de tâches successives ? ». Pour répondre à cette question, nous avons formulé deux hypothèses : 1. Une évaluation formative dynamique permettrait de favoriser la compréhension de la démarche scientifique par les élèves. 2. Les choix didactiques que l’enseignant.e effectue dans le cadre de ses enseignements de sciences auraient une influence significative sur les apprentissages en lien avec la démarche scientifique. Nous nous sommes alors renseignées à travers différentes lectures sur les concepts liés à notre questionnement. À partir de nos recherches, nous avons mis en œuvre en classe une séquence sur la démarche scientifique qui a porté sur les besoins de la plante. Tout au long de la séquence, nous avons récolté des données en classe, à savoir des traces d’élèves, des enregistrements, des traces du travail effectué en collectif, ou encore, le matériel utilisé. Enfin, sur la base de nos recherches et de la séquence réalisée en classe, nous avons tenté de répondre à notre problématique en reprenant l’ensemble de nos données récoltées et en les discutant. Au terme de notre travail, nous sommes arrivées à la conclusion que l’évaluation formative dynamique et les choix didactiques de l’enseignant ont une influence sur la compréhension et les apprentissages des élèves dans la démarche scientifique.
Ketamine for Postoperative Avoidance of Depressive Symptoms (K-PASS) Feasibility Study: A Randomized Clinical Trial
Creators: name: Fritz, Bradley
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Mental Disorders
subject: Chemicals and Drugs
subject: Anesthesiology
subject: Psychiatry and Psychology
subject: Medicine and Health Sciences
subject: Medical Specialties
subject: Surgery

description: This is a feasibility trial that will evaluate the feasibility of conducting a full-scale phase 3 trial. Both the feasibility trial and the full-scale trial will follow a randomized, placebo-controlled, double-blinded, parallel design. The trial will follow a superiority design. This trial will take place at a single site (Washington University in St. Louis School of Medicine/Barnes-Jewish Hospital). The primary hypothesis underlying this work is that a postoperative sustained, low-dose ketamine infusion can prevent postoperative depressive symptoms when administered to a targeted population of neurosurgical patients with a history of depression. On the day following extubation, patients will be randomized to the intervention (ketamine group) or to control (control group). Patients in the ketamine group will receive a bolus of ketamine 0.5 mg/kg intravenously over 10 minutes, followed by an infusion at 0.3 mg/kg/h for an additional 7 hours 50 minutes. Patients in the control group will receive an equal volume of normal saline. Additional details about dosing and administration are found in section 6.1.2. Patients, research staff performing assessments, and research staff performing data analysis will be blinded to treatment allocation.
Data-driven modeling of cellular stimulation, signaling and output response in RAW 264.7 cells
Creators: name: Johnson, Gary
name: Gomez, Shawn
name: Wu, Yang
Publisher: name: BioMed Central Ltd
Year: 2008

description: Abstract Background Understanding the relative importance of signaling pathway components which regulate a specific cellular response is a major focus of current efforts in biology. This interest, along with the inherit complexity of these systems, is driving the development of approaches capable of providing both quantitative predictions as well as guiding the design of future experiments. Of particular interest is the establishment of methods for the analysis of cellular-level input-output signaling relationships that have been characterized over time. Results Work by the Alliance for Cellular Signaling (AfCS) has provided an extensive profile of ligand-induced changes in protein phosphorylation state and cytokine output response in macrophage-like RAW 264.7 cells. Using model averaging with partial least squares (PLS) or principal components regression (PCR), we compared multivariate models quantitatively predicting cytokine release and identifying key regulatory components of the underlying signaling pathways. We paid particular attention to the effect of metrics extracted from the experimentally derived signaling time courses so as to determine whether the inclusion of such temporal information improved model predictions. Results indicate that we were able to determine the key biological predictors responsible for generating a specific cytokine response, with model R2 values ranging from 0.48 to 0.93. Furthermore, for this data set, the use of time metrics was found to be of mixed value, with increased and/or more appropriate sampling likely being required to improve predictive performance. Conclusion The use of multivariate approaches and model averaging provides a valuable predictive framework for quantitative studies of these complex biological processes. Results of this work also point to several issues for consideration in the design of similar large-scale interrogations.
APTrust Groupspace Wiki
Publisher: name: University of Virginia
Year: 2019
Subjects: aptrust
wiki
preservation

description: This site is created for use by APTrust individuals and teams for work on projects, for reporting best practices, and for other needs.  Everything in it should be accessible to the general public for viewing.

If you have signed up for the APTrust Community Google Group (https://groups.google.com/forum/#!forum/aptrust-community , which is free and open), you should be able to edit or comment on materials in these spaces.

Please let Chip know (chip.german@aptrust.org) if this site isn't working the way he thinks it is.
title: Imaging findings of papillary renal cell carcinoma
Creators: name: Praia, Joao
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Cancer
subject: Staging
subject: Diagnostic procedure
subject: Ultrasound
subject: MR
subject: CT
subject: Oncology
subject: Kidney
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: - Overview of the epidemiology, pathology and biology of renal cell carcinoma (RCC) and its different subtypes. - Description and discussion of the imaging findings of the papillary subtype (pRCC) and its impact on the treatment, prognosis and...
Measuring finite Quantum Geometries via Quasi-Coherent States
Creators: name: Schneiderbauer, Lukas
name: Steinacker, Harold C.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We develop a systematic approach to determine and measure numerically the geometry of generic quantum or "fuzzy" geometries realized by a set of finite-dimensional hermitian matrices. The method is designed to recover the semi-classical limit of quantized symplectic spaces embedded in $\mathbb{R}^d$ including the well-known examples of fuzzy spaces, but it applies much more generally. The central tool is provided by quasi-coherent states, which are defined as ground states of Laplace- or Dirac operators corresponding to localized point branes in target space. The displacement energy of these quasi-coherent states is used to extract the local dimension and tangent space of the semi-classical geometry, and provides a measure for the quality and self-consistency of the semi-classical approximation. The method is discussed and tested with various examples, and implemented in an open-source Mathematica package.
description: 41 pages, 14 figures. V2: discussion of Dirac operator improved, published version
title: Imaging Features of Tumor-like Conditions in Sinonasal Region
Creators: name: Mingkwansook, Varalee
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Neoplasia
subject: Inflammation
subject: Infection
subject: Diagnostic procedure
subject: Contrast agent-intravenous
subject: MR
subject: Fluoroscopy
subject: CT
subject: Head and neck
subject: Ear / Nose / Throat

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Our purpose is to provide an educational exhibit illustrating the computed tomography (CT) and magnetic resonance imaging (MRI) features of various tumor-like conditions in sinonasal region and use cases from our centre as illustrative...
Perturbation on Hyperfine-enhanced $^{141}$Pr Nuclear Spin Dynamics Associated with Antiferroquadrupolar Order in PrV$_2$Al$_{20}$
Creators: name: Ito, T. U.
name: Higemoto, W.
name: Sakai, A.
name: Tsujimoto, M.
name: Nakatsuji, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The nature of multipolar order and hyperfine-enhanced (HE) $^{141}$Pr nuclear spin dynamics in PrV$_2$Al$_{20}$ was investigated using the muon spin relaxation technique. No explicit sign of time-reversal symmetry breaking was found below the multipolar order temperature $T_Q\sim 0.6$ K in a zero applied field as anticipated on the basis of the antiferroquadrupolar (AFQ) order picture proposed by Sakai and Nakatsuji [J. Phys. Soc. Jpn. 80, 063701 (2011)]. Further evidence of the nonmagnetic ground state was obtained from the observation of HE $^{141}$Pr nuclear spin fluctuations in the MHz scale. A marked increase in the muon spin-lattice relaxation rate (1/$T_{\rm 1,μ}$) was observed below 1 K with decreasing temperature, which was attributed to the perturbation on the HE $^{141}$Pr nuclear spin dynamics associated with the development of AFQ correlations. The longitudinal field dependence of 1/$T_{\rm 1,μ}$ revealed that the enhanced $^{141}$Pr nuclear spin accidentally has an effective gyromagnetic ratio close to that of the muon.
description: 5 pages, 2 figures, accepted for publication in Phys. Rev. B (http://journals.aps.org/prb/)
Galactic Archaeology with [Mg/Mn] versus [Al/Fe] abundance ratios - Uncertainties and caveats
Creators: name: Vasini, Arianna
name: Spitoni, Emanuele
name: Matteucci, Francesca
Publisher: name: Zenodo
Year: 2023

description: In the last years the plane [Mg/Mn] vs. [Al/Fe] was proposed as a diagnostic for the star formation histories of the Milky Way and the nearby galaxies. Since these elements are produced by different stellar progenitors on different time scales, thanks to the time delay model, their combination can show the imprint left by the star formation of the environment in exam. In particular, different stellar population belonging to the same galaxy lie in different regions of the plane according to when they originated. It is therefore possible to highlight the accreted populations since their position on the [Mg/Mn] vs [Al/Fe] cannot be explained by the star formation history of the galaxy. Here, by the means of two chemical evolution models already tested (one for the mIlky Way and one for the LMC), we show which are the limitations concerning this diagram, in particular from the nucleosynthesis point of view. We present several tests performed with different parameters, to show the model dependency of the [Mg/Mn] vs [Al/Fe] trends for the MW and the LMC.
title: The potential role of high resolution ultrasound in evaluation of ankle sports injuries; a comparative study with high field MRI.
Creators: name: Kasem, Mohamed
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Athletic injuries
subject: Diagnostic procedure
subject: Ultrasound
subject: MR
subject: Musculoskeletal spine
subject: Musculoskeletal soft tissue

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To assesstherole ofhigh resolution ultrasonography in ankle sports injuries compared to high field...
Does using a Priority Evaluation Approach affect support for policies to reduce carbon emissions?
Creators: name: Lichtin, Florian
name: Smith, E.
name: Axhausen, Kay
name: Bernauer, Thomas
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Public Affairs, Public Policy and Public Administration
subject: Environmental Studies
subject: Political Science
subject: FOS: Political science
subject: Social and Behavioral Sciences

description: We investigate the impact of a highly individualized information treatment, the Priority Evaluator, on citizens perceptions of different types of efficacy and environmental policy preferences.
Model-independent characterisation of strong gravitational lenses
Creators: name: Wagner, Jenny
name: Bartelmann, Matthias
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We develop a new approach to extracting model-independent information from observations of strong gravitational lenses. The approach is based on the generic properties of images near the fold and cusp catastrophes in caustics and critical curves. Observables used are the relative image positions, the magnification ratios and ellipticities of extended images, and time delays between images with temporally varying intensity. We show how these observables constrain derivatives and ratios of derivatives of the lensing potential near a critical curve. Based on these measured properties of the lensing potential, classes of parametric lens models can then easily be restricted to such parameter values compatible with the measurements, thus allowing fast scans of large varieties of models. Applying our approach to a representative galaxy (JVAS B1422+231) and a galaxy-cluster lens (MACS J1149.5+2223), we show which model-independent information can be extracted in those cases and demonstrate that the parameters obtained by our approach for known parametric lens models agree well with those found by detailed model fitting.
description: 8 pages, 3 figures, submitted for publication to Astronomy & Astrophysics
Significance testing of rank cross-correlations between autocorrelated time series with short-range dependence
Creators: name: Lun, David
name: Fischer, Svenja
name: Viglione, Alberto
name: Blöschl, Günter
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Statistical dependency measures such as Kendall’s Tau or Spearman’s Rho are frequently used to analyse the coherence between time series in environmental data analyses. Autocorrelation of the data can, however, result in spurious cross correlations if not accounted for. Here, we present the asymptotic distribution of the estimators of Spearman’s Rho and Kendall’s Tau, which can be used for statistical hypothesis testing of cross-correlations between autocorrelated observations. The results are derived using U-statistics under the assumption of absolutely regular (or β-mixing) processes. These comprise many short-range dependent processes, such as ARMA-, GARCH- and some copula-based models relevant in the environmental sciences. We show that while the assumption of absolute regularity is required, the specific type of model does not have to be specified for the hypothesis test. Simulations show the improved performance of the modified hypothesis test for some common stochastic models and small to moderate sample sizes under autocorrelation. The methodology is applied to observed climatological time series of flood discharges and temperatures in Europe. While the standard test results in spurious correlations between floods and temperatures, this is not the case for the proposed test, which is more consistent with the literature on flood regime changes in Europe.
title: Dose-reduced CT with model-based iterative reconstruction and adaptive statistical iterative reconstruction for detecting pancreatic calcification
Creators: name: Yasaka, Koichiro
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Calcifications / Calculi
subject: Radiation safety
subject: Comparative studies
subject: CT
subject: Radioprotection / Radiation dose
subject: Pancreas
subject: Abdomen

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Iterative reconstruction (IR) algorithms of computed tomography (CT) , such as model-based iterative reconstruction (MBIR) and adaptive statistical iterative reconstruction (ASIR)gain much attention as strategies for reducing radiation...
Knockoff procedure for false discovery rate control in high-dimensional data streams
Creators: name: Tsang, Ka Wai
name: Tsung, Fugee
name: Xu, Zhihao
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Motivated by applications to root-cause identification of faults in high-dimensional data streams that may have very limited samples after faults are detected, we consider multiple testing in models for multivariate statistical process control (SPC). With quick fault detection, only small portion of data streams being out-of-control (OC) can be assumed. It is a long standing problem to identify those OC data streams while controlling the number of false discoveries. It is challenging due to the limited number of OC samples after the termination of the process when faults are detected. Although several false discovery rate (FDR) controlling methods have been proposed, people may prefer other methods for quick detection. With a recently developed method called Knockoff filtering, we propose a knockoff procedure that can combine with other fault detection methods in the sense that the knockoff procedure does not change the stopping time, but may identify another set of faults to control FDR. A theorem for the FDR control of the proposed procedure is provided. Simulation studies show that the proposed procedure can control FDR while maintaining high power. We also illustrate the performance in an application to semiconductor manufacturing processes that motivated this development.
Why is announcement training more effective than conversation training for introducing HPV vaccination? A theory-based investigation
Creators: name: Gilkey, Melissa B
name: Hall, Megan E
name: Malo, Teri L
name: Lathren, Christine R
name: Brewer, Noel T.
Publisher: name: BioMed Central
Year: 2018

description: Abstract Background Improving healthcare providers’ communication about HPV vaccination is critical to increasing uptake. We previously demonstrated that training providers to use presumptive announcements to introduce HPV vaccination improved uptake, whereas training them to use participatory conversations had no effect. To understand how communication training changed provider perceptions and communication practices, we evaluated intermediate outcomes and process measures from our randomized clinical trial, with a particular focus on identifying mechanisms that might explain the announcement training’s impact. Methods In 2015, a physician educator delivered 1-h in-clinic HPV vaccination recommendation trainings at 20 primary care clinics in North Carolina serving 11,578 patients age 11 or 12. Clinics were randomized to receive training to use “announcements” that presume parents are ready to vaccinate or “conversations” that invite dialog about vaccination. Training participants were 83 HPV vaccine providers. Pre- and post-training surveys assessed constructs from the theory of planned behavior (TPB), including providers’ attitudes and subjective norms about HPV vaccination and their perceived behavioral control to recommend HPV vaccination. Surveys also assessed providers’ perceptions of the announcement and conversation communication strategies. Results Both trainings improved TPB-related constructs, including providers’ positive attitudes toward HPV vaccination, subjective norms, and perceived behavioral control to recommend the vaccine (all p < .001, Cohen’s d = .62–.90). Furthermore, in both trainings, the amount of time providers reported needing to discuss HPV vaccination with parents decreased from pre-training to 1-month follow-up (mean = 3.8 vs. 3.2 min, p = .01, d = .28). However, announcement trainings outperformed conversation trainings on other measures. For example, providers who received announcement training more often reported that the communication strategy saved them time, was easy to use, helped them promote HPV vaccination as routine care, and increased HPV vaccination coverage in their clinics (all p < .05; d = .44–.60). Conclusions Both announcement and conversation trainings improved providers’ HPV vaccine-related perceptions. However, providers viewed announcements as easier to use and more effective, which may help to explain the success of this training approach. Future provider communication interventions should consider implementation outcomes, including acceptability, alongside more traditional TPB constructs. Trial registration clinicaltrials.gov, NCT02377843 . Registered on February 27, 2015.
title: Sonoelastography and Contrast Enhanced Ultrasound of Renal Masses: Are they useful for detection and characterization of benign and malignant renal lesions?
Creators: name: Kim, Sang Youn
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Kidney
subject: Ultrasound
subject: Elastography
subject: Diagnostic procedure
subject: Contrast agent-intravenous
subject: Cancer
subject: Cysts

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To show the image findings and the quantitative data of various renal lesions and to find out the usefulness of them for detection and characterization of benign and malignant renal...
C-terminal processing of yeast Spt7 occurs in the absence of functional SAGA complex
Creators: name: Liang, Gaoyang
Publisher: name: BioMed Central Ltd
Year: 2007

description: Abstract Background Spt7 is an integral component of the multi-subunit SAGA complex that is required for the expression of ~10% of yeast genes. Two forms of Spt7 have been identified, the second of which is truncated at its C-terminus and found in the SAGA-like (SLIK) complex. Results We have found that C-terminal processing of Spt7 to its SLIK form (Spt7SLIK) and to a distinct third form (Spt7Form3) occurs in the absence of the SAGA complex components Gcn5, Spt8, Ada1 and Spt20, the latter two of which are required for the integrity of the complex. In addition, N-terminally truncated derivatives of Spt7, including a derivative lacking the histone fold, are processed, indicating that the C-terminus of Spt7 is sufficient for processing and that processing does not require functional Spt7. Using galactose inducible Spt7 expression, we show that the three forms of Spt7 appear and disappear at approximately the same rate with full-length Spt7 not being chased into Spt7SLIK or Spt7Form3. Interestingly, reduced levels of Spt7SLIK and Spt7Form3 were observed in a strain lacking the SAGA component Ubp8, suggesting a regulatory role for Ubp8 in the truncation of Spt7. Conclusion We conclude that truncation of Spt7 occurs early in the biosynthesis of distinct Spt7 containing complexes rather than being a dynamic process linked to the action of the SAGA complex in transcriptional regulation.