cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
sj-docx-1-jic-10.1177_08850666231186947 - Supplemental material for Discordance Between Invasive and NonInvasive Oxygen Saturation in Critically Ill COVID-19 Patients
Creators: name: Fox, Thomas H.
name: Mazalewski, William R.
name: Tran, Hai S.
name: Lindsey, Travis
name: Krishnan, Amita
name: Kantrow, Stephen P.
name: Happel, Kyle I.
name: Janz, David R.
name: deBoisblanc, Bennett P.
name: Lammi, Matthew R.
Publisher: name: SAGE Journals
Year: 2023
Subjects: classificationCode: 110305
subject: Emergency Medicine
classificationCode: 111702
subject: Aged Health Care
classificationCode: 110203
subject: Respiratory Diseases

description: Supplemental material, sj-docx-1-jic-10.1177_08850666231186947 for Discordance Between Invasive and NonInvasive Oxygen Saturation in Critically Ill COVID-19 Patients by Thomas H. Fox, MD, William R. Mazalewski, DO, Hai S. Tran, MD, Travis Lindsey, MD, Amita Krishnan, MD, Stephen P. Kantrow, MD, Kyle I. Happel, MD, FCCP, David R. Janz, MD, Bennett P. deBoisblanc, MD, FACP, FCCP, FCCM, and Matthew R. Lammi, MD, MSCR in Journal of Intensive Care Medicine
Supplemental Material - Interventions for youth suicide and suicide-related behaviour: An update to a systematic review
Creators: name: Bailey, Eleanor
name: Robinson, Jo
name: Witt, Katrina
Publisher: name: SAGE Journals
Year: 2023
Subjects: classificationCode: 170199
subject: Psychology not elsewhere classified
classificationCode: 110319
subject: Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental Material for Interventions for youth suicide and suicide-related behaviour: an update to a systematic review by Eleanor Bailey, Jo Robinson, and Katrina Witt. Australasian Psychiatry
A Mediated Moderation between Firm Size and the Level of Voluntary Disclosure Index of Companies Listed on the SET
Creators: name: Jakkravudhi Chobpichien
Publisher: name: Office of Journal of Management Science
Year: 2018
Subjects: Firm Size
Quality of Board of Directors Index
CEO Controlling Ownership
Voluntary Disclosure Index
The Stock Exchange of Thailand (SET)

description: Journal of Management Science, Suratthani Rajabhat University, 5, 1, 15
Additional file 1 of A bias-reduced generalized estimating equation approach for proportional odds models with small-sample longitudinal ordinal data
Creators: name: Tada, Yukio
name: Sato, Tosiya
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Supplementary Material 1.
A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue
Creators: name: Makowski, Liza
name: Ptacek, Travis S
name: Schrank, Travis P
name: Major, Michael B
name: Mulvaney, Kathleen M
name: Montgomery, Stephanie A
name: Randell, Scott H
name: Weissman, Bernard E
name: Tamir, Tigist Y
name: Chen, Xiaoxin L
name: Nguyen, Tuong T
name: Weir, Seth J
name: Murphy, Ryan M
name: Bowman, Brittany M
name: Simon, Jeremy M
name: Hayes, D Neil
Publisher: name: Wiley
Year: 2020

description: Activation of the nuclear factor (erythroid-derived 2)-like 2 (NFE2L2 or NRF2) transcription factor is a critical and evolutionarily conserved cellular response to oxidative stress, metabolic stress, and xenobiotic insult. Deficiency of NRF2 results in hypersensitivity to a variety of stressors, whereas its aberrant activation contributes to several cancer types, most commonly squamous cell carcinomas of the esophagus, oral cavity, bladder, and lung. Between 10% and 35% of patients with squamous cell carcinomas display hyperactive NRF2 signaling, harboring activating mutations and copy number amplifications of the NFE2L2 oncogene or inactivating mutations or deletions of KEAP1 or CUL3, the proteins of which co-complex to ubiquitylate and degrade NRF2 protein. To better understand the role of NRF2 in tumorigenesis and more broadly in development, we engineered the endogenous Nfe2l2 genomic locus to create a conditional mutant LSL-Nrf2E79Q mouse model. The E79Q mutation, one of the most commonly observed NRF2-activating mutations in human squamous cancers, codes for a mutant protein that does not undergo KEAP1/CUL3-dependent degradation, resulting in its constitutive activity. Expression of NRF2 E79Q protein in keratin 14 (KRT14)-positive murine tissues resulted in hyperplasia of squamous cell tissues of the tongue, forestomach, and esophagus, a stunted body axis, decreased weight, and decreased visceral adipose depots. RNA-seq profiling and follow-up validation studies of cultured NRF2E79Q murine esophageal epithelial cells revealed known and novel NRF2-regulated transcriptional programs, including genes associated with squamous cell carcinoma (e.g. Myc), lipid and cellular metabolism (Hk2, Ppard), and growth factors (Areg, Bmp6, Vegfa). These data suggest that in addition to decreasing adipogenesis, KRT14-restricted NRF2 activation drives hyperplasia of the esophagus, forestomach, and tongue, but not formation of squamous cell carcinoma.
Integrative Analysis of miRNAs Identifies Clinically Relevant Epithelial and Stromal Subtypes of Head and Neck Squamous Cell Carcinoma
Creators: name: Wilkerson, Matthew D.
name: Hayes, David Neil
name: Ko, Yoon Ho
name: Yin, Xiaoying
name: Jo, Heejoon
name: Marron, David
name: Walter, Vonn
name: Holt, Jeremiah
name: Choi, Hyo Young
name: Zhao, Xiaobei
Publisher: name: American Association for Cancer Research (AACR)
Year: 2021

description: PURPOSE: The objective of this study is to characterize the role of miRNAs in the classification of head and neck squamous cell carcinoma (HNSCC). EXPERIMENTAL DESIGN: Here, we analyzed 562 HNSCC samples, 88 from a novel cohort and 474 from The Cancer Genome Atlas, using miRNA microarray and miRNA sequencing, respectively. Using an integrative correlations method followed by miRNA expression-based hierarchical clustering, we validated miRNA clusters across cohorts. Evaluation of clusters by logistic regression and gene ontology approaches revealed subtype-based clinical and biological characteristics. RESULTS: We identified two independently validated and statistically significant (P < 0.01) tumor subtypes and named them "epithelial" and "stromal" based on associations with functional target gene ontology relating to differing stages of epithelial cell differentiation. miRNA-based subtypes were correlated with individual gene expression targets based on miRNA seed sequences, as well as with miRNA families and clusters including the miR-17 and miR-200 families. These correlated genes defined pathways relevant to normal squamous cell function and pathophysiology. miRNA clusters statistically associated with differential mutation patterns including higher proportions of TP53 mutations in the stromal class and higher NSD1 and HRAS mutation frequencies in the epithelial class. miRNA classes correlated with previously reported gene expression subtypes, clinical characteristics, and clinical outcomes in a multivariate Cox proportional hazards model with stromal patients demonstrating worse prognoses (HR, 1.5646; P = 0.006). CONCLUSIONS: We report a reproducible classification of HNSCC based on miRNA that associates with known pathologically altered pathways and mutations of squamous tumors and is clinically relevant.
Long range early diagnosis of Alzheimer's disease using longitudinal MR imaging data
Creators: name: Zhu, Xiaofeng
name: Kaufer, Daniel
name: Zhu, Yingying
name: Alzheimer's Disease Neuroimaging Initiative
name: Wu, Guorong
name: Kim, Minjeong
Publisher: name: Elsevier
Year: 2020

description: The enormous social and economic cost of Alzheimer's disease (AD) has driven a number of neuroimaging investigations for early detection and diagnosis. Towards this end, various computational approaches have been applied to longitudinal imaging data in subjects with Mild Cognitive Impairment (MCI), as serial brain imaging could increase sensitivity for detecting changes from baseline, and potentially serve as a diagnostic biomarker for AD. However, current state-of-the-art brain imaging diagnostic methods have limited utility in clinical practice due to the lack of robust predictive power. To address this limitation, we propose a flexible spatial-temporal solution to predict the risk of MCI conversion to AD prior to the onset of clinical symptoms by sequentially recognizing abnormal structural changes from longitudinal magnetic resonance (MR) image sequences. Firstly, our model is trained to sequentially recognize different length partial MR image sequences from different stages of AD. Secondly, our method is leveraged by the inexorably progressive nature of AD. To that end, a Temporally Structured Support Vector Machine (TS-SVM) model is proposed to constrain the partial MR image sequence's detection score to increase monotonically with AD progression. Furthermore, in order to select the best morphological features for enabling classifiers, we propose a joint feature selection and classification framework. We demonstrate that our early diagnosis method using only two follow-up MR scans is able to predict conversion to AD 12 months ahead of an AD clinical diagnosis with 81.75% accuracy.
Additional file 1 of Concordance between head and neck MRI and histopathology in detecting laryngeal subsite invasion among patients with laryngeal cancer
Creators: name: Mohamad, Issa
name: Hejleh, Taher Abu
name: Qandeel, Monther
name: Al-Hussaini, Maysa
name: Koro, Sami
name: Taqash, Ayat
name: Almousa, Abdelatif
name: Abuhijla, Fawzi
name: Abuhijlih, Ramiz
name: Ajlouni, Fatenah
name: Al-Ibraheem, Akram
name: Laban, Dima Abu
name: Hussein, Tariq
name: Mayta, Ebrahim
name: Al-Gargaz, Wisam
name: Hosni, Ali
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Cancer

description: Additional file 1: Supplementary table 1. Radiologists demographics.
Reproducibility, sharing and progress in nanomaterial databases
Creators: name: Tropsha, Alexander
name: Hickey, Anthony J.
name: Mills, Karmann C.
Publisher: name: Springer Nature
Year: 2017

description: Publicly accessible databases are core resources for data-rich research, consolidating field-specific knowledge and highlighting best practices and challenges. Further effective growth of nanomaterial databases requires the concerted efforts of database stewards, researchers, funding agencies and publishers.
Repose: An Aircraft Cabin Design Research To Improve The In-Flight Sleep Of Long Haul Economy Passengers
Creators: name: NYEIN CHAN AUNG
Publisher: name: Monash University
Year: 2018
Subjects: subject: 120305 Industrial Design
subject: FOS: Arts (arts, history of arts, performing arts, music)
subject: Design

description: This exegesis accompanies the Repose Cabin, an aircraft cabin concept design that enhances sleep for passengers in the economy class cabin during long-haul flights. The work resulted from a studio based PhD design research program and stood apart from existing products in that sleep enhancement solutions are provided from the design of the aircraft cabin environment and architecture instead of the design of the seats. The exegesis functions as a concise presentation of the research framework and a critical examination of the design output.
LA VEILLE STRATEGIQUE AU SEIN DE L’ENTREPRISE : QUELQUES REPERES
Creators: name: NANECHE, Fariza
Publisher: name: Revue Economie, Gestion et Société
Year: 2016
Subjects: Compétitivité ; décision ; entreprise ; environnement ; information ; veille stratégique.

description: Si le concept de veille stratégique est largement répandu et mieux appréhendé en France et aux pays d’outre-Atlantique, ce dernier demeure encore insaisissable et ainsi peu ou prou intégré au sein des entreprises du grand Maghreb, et en particulier, celles Algériennes. Cet article pour toute fin utile se veut descriptif, munies d’une revue de littérature, nous avons mis en exergue certaines facettes du processus de veille stratégique, à l’instar de la délimitation du concept de veille, de l’exposition de ses composantes constitutives, de son processus cyclique, des alternatives de son implantation et pour inciter l’appropriation de cet outil managérial, les avantages susceptibles d’être engendrés par son intégration au sein de l’entreprise sont répertoriés et ce, sans aucune prétention à l’exhaustivité.
description: Revue Economie, Gestion et Société, No 6 (2016)
Multi-Descriptor Read Across (MuDRA): A Simple and Transparent Approach for Developing Accurate Quantitative Structure-Activity Relationship Models
Creators: name: Muratov, Eugene N.
name: Tropsha, Alexander
name: Golbraikh, Alexander
name: Capuzzi, Stephen J.
name: Liu, Kammy
name: Andrade, Carolina Horta
name: Lam, Wai In
name: Korn, Daniel Robert
name: Pozefsky, Diane
name: Alves, Vinicius M.
Publisher: name: American Chemical Society (ACS)
Year: 2018

description: Multiple approaches to quantitative structure-activity relationship (QSAR) modeling using various statistical or machine learning techniques and different types of chemical descriptors have been developed over the years. Oftentimes models are used in consensus to make more accurate predictions at the expense of model interpretation. We propose a simple, fast, and reliable method termed Multi-Descriptor Read Across (MuDRA) for developing both accurate and interpretable models. The method is conceptually related to the well-known kNN approach but uses different types of chemical descriptors simultaneously for similarity assessment. To benchmark the new method, we have built MuDRA models for six different end points (Ames mutagenicity, aquatic toxicity, hepatotoxicity, hERG liability, skin sensitization, and endocrine disruption) and compared the results with those generated with conventional consensus QSAR modeling. We find that models built with MuDRA show consistently high external accuracy similar to that of conventional QSAR models. However, MuDRA models excel in terms of transparency, interpretability, and computational efficiency. We posit that due to its methodological simplicity and reliable predictive accuracy, MuDRA provides a powerful alternative to a much more complex consensus QSAR modeling. MuDRA is implemented and freely available at the Chembench web portal ( https://chembench.mml.unc.edu/mudra ).
Additional file 1 of Caregiving information needs of family caregivers of adolescent patients with suicide attempts: a qualitative study in China
Creators: name: Wang, Xiaoning
name: Miu, Qunfang
name: Wang, Jiannv
name: Huang, Xiaoyu
name: Xie, Wenru
Publisher: name: figshare
Year: 2024
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1
60790: Letter from Dr W.R. Blore M.C. RAMC
Creators: name: Project Team, Great War Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: This is an extract from a photocopy of a letter from Dr W.R. Blore M.C. RAMC sent on 7th March 1916, from Egypt. It describes a photo which is enclosed, of Dr Blore outside his dugout at Suvla Bay, Gallipoli in 1915. That dugout was sketched in his letter of 14th October. In this letter he mentions the chair in the photo which was actually shipped over from England in his luggage, and which was evacuated to Egypt. Blore also describes his hair-cut and his uniform.
Also part of this collection are the photograph described here, and the sketch from the earlier letter as well as all Blore's letters home, his notebooks from his service as a doctor at Suvla Bay, Gallipoli, and on the Western Front - as well as his sleeping bag and many other artefacts.
A universal allosteric mechanism for G protein activation
Creators: name: Dohlman, Henrik G
name: Valentin, Natalie H
name: Vaidehi, Nagarajan
name: Yin, Guowei
name: Knight, Kevin M
name: Campbell, Sharon L
name: Smrcka, Alan V
name: Lefevre, Tyler J
name: Ghosh, Soumadwip
name: Olsen, Reid H J
Publisher: name: Elsevier
Year: 2021

description: G proteins play a central role in signal transduction and pharmacology. Signaling is initiated by cell-surface receptors, which promote guanosine triphosphate (GTP) binding and dissociation of Gα from the Gβγ subunits. Structural studies have revealed the molecular basis of subunit association with receptors, RGS proteins, and downstream effectors. In contrast, the mechanism of subunit dissociation is poorly understood. We use cell signaling assays, molecular dynamics (MD) simulations, and biochemistry and structural analyses to identify a conserved network of amino acids that dictates subunit release. In the presence of the terminal phosphate of GTP, a glycine forms a polar network with an arginine and glutamate, putting torsional strain on the subunit binding interface. This "G-R-E motif" secures GTP and, through an allosteric link, discharges the Gβγ dimer. Replacement of network residues prevents subunit dissociation regardless of agonist or GTP binding. These findings reveal the molecular basis of the final committed step of G protein activation.
66099: After War
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Manuscript in pen in Ivor Gurney's hand. The 'wedges and streaks' refer to shapes made by candlelight as described in other poems. An alternative typescript exists with added lines. The draft show here was included in Leonard Clark's edition of Gurney's poems of 1973, and in P.J. Kavanagh's 'Ivor Gurney: Collected Poems' (2004). From a pink mottled hard-cover exercise book. The inside front cover is inscribed 'Music to Miss C. Rogers...Poetry to Professor Saintsbury / Bath'. The inside back cover is inscribed 'Instead of a home / I require death'.
sj-pdf-2-pev-10.1177_22840265221093263 – Supplemental material for Current diagnosis and management of adenomyosis in Canada: A survey of Canadian gynaecologists
Creators: name: Maxim, Madalina
name: Dason, Ebernella Shirin
name: Chan, Crystal
name: Luketic, Lea
name: Li, Qixuan
name: Huszti, Ella
name: P. Sanders, Ari
name: Sobel, Mara
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111402 Obstetrics and Gynaecology
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-2-pev-10.1177_22840265221093263 for Current diagnosis and management of adenomyosis in Canada: A survey of Canadian gynaecologists by Madalina Maxim, Ebernella Shirin Dason, Crystal Chan, Lea Luketic, Qixuan Li, Ella Huszti, Ari P. Sanders and Mara Sobel in Journal of Endometriosis and Pelvic Pain Disorders
CAPITAL HUMAIN ET CROISSANCE ECONOMIQUE: ANALYSE EMPIRIQUE DU MODELE DE SOLOW AUGMENTE
Creators: name: GUATI, Rizlane
name: AAMOUM, Hanane
Publisher: name: Revue Economie, Gestion et Société
Year: 2016
Subjects: Capital humain, Education, Croissance, modèle de Solow, données de panel.

description: Dans cet article, nous estimons le modèle de Solow augmenté pour vérifier si la relation capital humain et croissance est vérifiée dans trois régions : Asie-Pacifique, Amérique Latine- Caraïbes et Afrique. Nos estimations portent sur la période 1965-2010 et s’appuient sur les méthodes de Moindres Carrés Généralisées. Les résultats empiriques affirment les hypothèses du modèle et montrent que dans les pays des trois régions étudiées, le capital humain, représenté par le nombre moyen des années d’études dans le secondaire et le supérieur, contribue positivement et significativement à la croissance économique.
description: Revue Economie, Gestion et Société, No 6 (2016)
sj-docx-2-sjp-10.1177_14034948221088003 – Supplemental material for Socioeconomic differences in the association between maternal age and maternal obesity: a register-based study of 707,728 women in Finland
Creators: name: Roustaei, Zahra
name: Räisänen, Sari
name: Gissler, Mika
name: Heinonen, Seppo
Publisher: name: SAGE Journals
Year: 2022
Subjects: Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-docx-2-sjp-10.1177_14034948221088003 for Socioeconomic differences in the association between maternal age and maternal obesity: a register-based study of 707,728 women in Finland by Zahra Roustaei, Sari Räisänen, Mika Gissler and Seppo Heinonen in Scandinavian Journal of Public Health
IL-11 antagonist suppresses Th17 cell-mediated neuroinflammation and demyelination in a mouse model of relapsing-remitting multiple sclerosis
Creators: name: Zhang, Xin
name: Midkiff, Bentley R
name: Shih, Yen-Yu I
name: Cohen, Stephanie M
name: Kiapour, Nazanin
name: Markovic-Plese, Silva
name: Kapoor, Sahil
name: Ban, Woomi
name: Merrill, Joseph R
name: Jewells, Valerie
name: Xia, Yongjuan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: IL-11 induced differentiation and expansion of Th17 cells in patients with early relapsing-remitting multiple sclerosis (RRMS). In mice with relapsing-remitting experimental autoimmune encephalomyelitis (RREAE), IL-11 exacerbated disease, induced demyelination in the central nervous system (CNS), increased the percentage of IL-17A+CD4+ Th17 cells in the CNS in the early acute phase, and up-regulated serum IL-17A levels and the percentage of IL-17A+CD4+ Th17 cells in lymph nodes, and IFN-γ+CD4+ T cells in spinal cord in the RR phase. IL-11 antagonist suppressed RREAE disease activities, inhibited IL-17A+CD4+ cell infiltration and demyelination in the CNS, and decreased the percentage of IL-17A+CD4+ T cells in peripheral blood mononuclear cells and ICAM1+CD4+ T cells in brain and SC. Diffusion Tensor Imaging indicated that IL-11 antagonist inhibited demyelination in several brain regions. We conclude that by suppressing Th17 cell-mediated neuroinflammation and demyelination, IL-11 antagonist can be further studied as a potential selective and early therapy for RRMS.
sj-docx-1-eso-10.1177_23969873221146591 – Supplemental material for Is the socioeconomic inequality in stroke prognosis changing over time and does quality of care play a role?
Creators: name: Hyldgård, Vibe Bolvig
name: Søgaard, Rikke
name: Valentin, Jan Brink
name: Lange, Theis
name: Damgaard, Dorte
name: Johnsen, Søren Paaske
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Cardiology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-eso-10.1177_23969873221146591 for Is the socioeconomic inequality in stroke prognosis changing over time and does quality of care play a role? by Vibe Bolvig Hyldgård, Rikke Søgaard, Jan Brink Valentin, Theis Lange, Dorte Damgaard and Søren Paaske Johnsen in European Stroke Journal
Topological Signatures Of 0Nldbd Events On A Stripped 2-Dimensional Readout At A High Pressure Xenon Tpc
Creators: name: GALAN, Javier
Publisher: name: Zenodo
Year: 2018

description: The search for the neutrinoless double beta decay (0νββ
\nu\beta\beta
) is one of the most important quests nowadays in neutrino physics. Among the different techniques used, High Pressure Xenon (HPXe) gas Time Projection Chambers (TPC) stand out because they allow to image the topology of the 0νββ
\nu\beta\beta
event (one straggling track ending in two blobs), and use it to discriminate signal from background.

Reducing the number of channels required to register the events helps to miniaturize electronics and its impact on the background budget of the experiment. The microbulk detector readout conceived for PandaX-III uses stripped channels in x and y, reducing considerably the number of channels required in comparison to a pixelated readout. This necessary channel reduction leads to two projected track images, losing full 3-dimensional track reconstruction capability. In this work, we assess the impact of this readout and the benefits of increasing detector granularity on a HPXe TPC.
Table S1 - Supplemental material for The Incidence, Prevalence, and Mortality of Vitiligo in Korea: A Nationwide Population-Based Cohort Study
Creators: name: Lee, Young Bok
name: Kim, Suyeon
name: Kim, Hei Sung
Publisher: name: SAGE Journals
Year: 2022
Subjects: Medicine

description: Supplemental material, Table S1, for The Incidence, Prevalence, and Mortality of Vitiligo in Korea: A Nationwide Population-Based Cohort Study by Young Bok Lee, Suyeon Kim and Hei Sung Kim in Journal of Cutaneous Medicine and Surgery
Longitudinal associations of blood pressure with aortic stiffness and pulsatility: the Atherosclerosis Risk in Communities Study
Creators: name: Folsom, Aaron R.
name: Agarwal, Sunil K.
name: Windham, B. Gwen
name: Cheng, Susan
name: Meyer, Michelle L.
name: Heiss, Gerardo
name: Couper, David
name: Tanaka, Hirofumi
name: Metcalf, Patricia A.
Publisher: name: Wolters Kluwer
Year: 2021

description: OBJECTIVE: To characterize the longitudinal relationships between blood pressure measured over 24 years and arterial stiffness in late life measured as pulse wave velocity (PWV). METHODS: Carotid--femoral (cf) and femoral--ankle (fa) PWV were measured in 4166 adults at the visit 5 Atherosclerosis Risk in Communities study cohort examination (2011-2013). Participants were categorized into tertiles of PWV measurements. Blood pressure measurements were made at baseline (1987-1989), three subsequent triennial examinations, and visit 5. RESULTS: Partial correlation coefficients between visit 5 cfPWV and SBP ranged from 0.13 for visit 1 SBP to 0.32 for visit 5 SBP. For visit 5 faPWV, correlations were ~0 for visits 1 to 4 SBP, but was 0.20 for visit 5 SBP. Over 24 years of follow-up, those with higher average SBP were more likely to fall in the middle and upper tertiles of visit 5 cfPWV. Average pulse pressure and mean arterial pressure over 24 years had similar but weaker associations with cfPWV tertiles. DBP had no clear association with cfPWV. Blood pressure measurements were positively associated with faPWV tertiles only cross-sectionally at visit 5. CONCLUSION: Adult life-course measures of SBP, more so than mean arterial and pulse pressure, were associated with later life central arterial stiffness. By contrast, only contemporaneous measures of blood pressure were associated with peripheral arterial stiffness. Although arterial stiffness was only measured at later life, these results are consistent with the notion that elevated blood pressure over time is involved in the pathogenesis of arterial stiffening.
56026: Letter: To Siegfried Sassoon / Letter to S. from Bryn-y-pin / The Leveller
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Comments on Siegfried Sassoon's wounds and the possibility of seeing a sister of Robert Graves' who is in Boulogne / includes ten lines of a poem later titled 'Letter to S. S. from Bryn-y-pin', included in 'The Patchwork Flag' and written anticipating Sassoon's death / reports of the sudden death from the flu and pneumonia of Nancy Nicholson's mother / comments on the potential for the end of the war and Graves' opinion of American war aims / plans for and concerns about buying and running a dairy farm in Sussex / potential for Sassoon to aid Graves and Nancy financially / alludes to a 'trench poem' written recently by Graves entitled 'The Leveller', included with the letter / comments that two years prior Graves was writing in Mametz Wood. Contains also a letter to Sassoon from Bryn-y-pin on 9th July 1918.
sj-pdf-1-cep-10.1177_03331024221131331 - Supplemental material for Comparison of continuous headache features in youth with migraine, new daily persistent headache, and persistent post-traumatic headache
Creators: name: Patterson Gentile, Carlyn
name: Aguirre, Geoffrey K
name: Hershey, Andrew D
name: Szperka, Christina L
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, sj-pdf-1-cep-10.1177_03331024221131331 for Comparison of continuous headache features in youth with migraine, new daily persistent headache, and persistent post-traumatic headache by Carlyn Patterson Gentile, Geoffrey K Aguirre, Andrew D Hershey and Christina L Szperka in Cephalalgia
Synthesis and structure activity relationships of DCLK1 kinase inhibitors based on a 5,11-dihydro-6H-benzo[e]pyrimido[5,4-b] [1,4]diazepin-6-one scaffold
Creators: name: Muthuswamy, Senthil
name: Capuzzi, Stephen J.
name: Westover, Kenneth D.
name: Muratov, Eugene N.
name: Wang, Jinhua
name: Harshbarger, Wayne
name: Gray, Nathanael S.
name: Huang, Ling
name: Tropsha, Alexander
name: Deng, Xianming
name: Liu, Yan
name: Ferguson, Fleur M.
Publisher: name: American Chemical Society (ACS)
Year: 2020

description: Doublecortin-like kinase 1 (DCLK1) is a serine/threonine kinase that is overexpressed in gastrointestinal cancers, including esophageal, gastric, colorectal, and pancreatic cancers. DCLK1 is also used as a marker of tuft cells, which regulate type II immunity in the gut. However, the substrates and functions of DCLK1 are understudied. We recently described the first selective DCLK1/2 inhibitor, DCLK1-IN-1, developed to aid the functional characterization of this important kinase. Here we describe the synthesis and structure-activity relationships of 5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one DCLK1 inhibitors, resulting in the identification of DCLK1-IN-1.
66058: The Fire Kindled
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Manuscript in pen in Marion Scott's hand. Mentioned in two letters of 3rd February 1917 to Marion Scott. Included in 'Severn and Somme' (1917).
Additional file 1 of Stakeholder development of an implementation strategy for fall prevention in Norwegian home care – a qualitative co-creation approach
Creators: name: Linnerud, Siv
name: Kvael, Linda Aimee Hartford
name: Graverholt, Birgitte
name: Idland, Gro
name: Taraldsen, Kristin
name: Brovold, Therese
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 1
sj-docx-2-jia-10.1177_23259582221144448 - Supplemental material for “It’s Still in the Test Tube and Finding out How the Experiment Ends… ”. A Qualitative Study on Health and Aging in Older Gay Males Living with HIV in England
Creators: name: Licchelli, Stefano
name: King, Andrew
name: Smith, Kimberley J.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111702 Aged Health Care
subject: 111799 Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-docx-2-jia-10.1177_23259582221144448 for “It’s Still in the Test Tube and Finding out How the Experiment Ends… ”. A Qualitative Study on Health and Aging in Older Gay Males Living with HIV in England by Stefano Licchelli, Andrew King and Kimberley J. Smith in Journal of the International Association of Providers of AIDS Care (JIAPAC)
Radioactive Background Control For The  Juno Experimental Setup
Creators: name: SISTI, Monica
Publisher: name: Zenodo
Year: 2018

description: The Jiangmen Underground Neutrino Observatory (JUNO) is a 20 kton multiple-purpose experiment with the primary goal of determining the neutrino mass hierarchy. To reach the needed physics sensitivity it is required to reduce the single trigger count rate to less than 10 Hz in the fiducial volume. Therefore, it is crucial to carefully select the radiopurity of all materials used to build the detector and to keep under control the environmental background. In this poster we present the current investigations on the impurity concentration of the various detector components and the expected background count rate in the energy region of interest.
Pathology and Molecular Characteristics of Pancreatic Cancer
Creators: name: Yeh, Jen Jen
name: Kearney, Joseph F
name: Adsay, Volkan
Publisher: name: Elsevier
Year: 2021

description: Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer. However, it should be kept in mind that there are other pancreatic cancers that are classified by their cellular lineage: acinar cell carcinomas (acinar differentiation), neuroendocrine neoplasms (arising from the islets), solid-pseudopapillary neoplasms (showing no discernible cell lineage), and pancreatoblastomas (characterized by multiphenotypic differentiation, including acinar endocrine and ductal). This article focuses on the molecular and pathology alterations in PDAC.
Supplemental Material - The effect of M technique massage on behavioral state and weight gain in preterm neonates: A randomized controlled trial
Creators: name: Alinejad-Naeini, Mona
name: Heidari-Beni, Farshad
name: Mohagheghi, Parisa
name: Sohrabi, Soroor
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111099 Nursing not elsewhere classified
subject: 111403 Paediatrics
subject: FOS: Clinical medicine

description: Supplemental Material for The effect of M technique massage on behavioral state and weight gain in preterm neonates: A randomized controlled trial by Mona Alinejad-Naeini, Farshad Heidari-Beni, Parisa Mohagheghi and Soroor Sohrabi in Journal of Child Health Care
Additional file 5 of Concordance between head and neck MRI and histopathology in detecting laryngeal subsite invasion among patients with laryngeal cancer
Creators: name: Mohamad, Issa
name: Hejleh, Taher Abu
name: Qandeel, Monther
name: Al-Hussaini, Maysa
name: Koro, Sami
name: Taqash, Ayat
name: Almousa, Abdelatif
name: Abuhijla, Fawzi
name: Abuhijlih, Ramiz
name: Ajlouni, Fatenah
name: Al-Ibraheem, Akram
name: Laban, Dima Abu
name: Hussein, Tariq
name: Mayta, Ebrahim
name: Al-Gargaz, Wisam
name: Hosni, Ali
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Cancer

description: Additional file 5: Supplementary table 5. presents the sensitivity, specificity, negative predictive value, positive predictive value, and accuracy of the DWI HN-MRI sequence when predicting tumor extension into laryngeal subsites, in comparison to the findings from histopathological assessments for patients who underwent total laryngectomy.
Supplemental Material - Polarization in COVID-19 Vaccine Discussion Networks
Creators: name: Amlani, Sharif
name: Kiesel, Spencer
name: Butters, Ross
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material for Polarization in COVID-19 Vaccine Discussion Networks by Sharif Amlani, Spencer Kiesel, and Ross Butters in American Politics Research
High-Dimensional Precision Medicine From Patient-Derived Xenografts
Creators: name: Zhang, Yunshu
name: Chen, Jingxiang
name: Yeh, Jen Jen
name: Zeng, Donglin
name: Lawson, Michael T.
name: Laber, Eric B.
name: Liu, Yufeng
name: Luckett, Daniel J.
name: Wang, Longshaokan
name: Kosorok, Michael R.
name: Rashid, Naim U.
Publisher: name: Taylor & Francis
Year: 2020

description: The complexity of human cancer often results in significant heterogeneity in response to treatment. Precision medicine offers the potential to improve patient outcomes by leveraging this heterogeneity. Individualized treatment rules (ITRs) formalize precision medicine as maps from the patient covariate space into the space of allowable treatments. The optimal ITR is that which maximizes the mean of a clinical outcome in a population of interest. Patient-derived xenograft (PDX) studies permit the evaluation of multiple treatments within a single tumor, and thus are ideally suited for estimating optimal ITRs. PDX data are characterized by correlated outcomes, a high-dimensional feature space, and a large number of treatments. Here we explore machine learning methods for estimating optimal ITRs from PDX data. We analyze data from a large PDX study to identify biomarkers that are informative for developing personalized treatment recommendations in multiple cancers. We estimate optimal ITRs using regression-based (Q-learning) and direct-search methods (outcome weighted learning). Finally, we implement a superlearner approach to combine multiple estimated ITRs and show that the resulting ITR performs better than any of the input ITRs, mitigating uncertainty regarding user choice. Our results indicate that PDX data are a valuable resource for developing individualized treatment strategies in oncology. Supplementary materials for this article are available online.
sj-docx-1-jom-10.1177_01492063221145130 - Supplemental material for A Tale of Two Types of Standard Setting: Evidence From Artificial Intelligence in China
Creators: name: Zhang, Jiamin
name: Li, Xiaohua
name: Tong, Tony
Publisher: name: SAGE Journals
Year: 2023
Subjects: Organisation and Management Theory

description: Supplemental material, sj-docx-1-jom-10.1177_01492063221145130 for A Tale of Two Types of Standard Setting: Evidence From Artificial Intelligence in China by Jiamin Zhang, Xiaohua Li, and Tony Tong in Journal of Management
Supplemental Material - A hybrid modeling approach considering spatial heterogeneity and nonlinearity to discover the transition rules of urban cellular automata models
Creators: name: Zeng, Haoran
name: Zhang, Bin
name: Wang, Haijun
Publisher: name: SAGE Journals
Year: 2023
Subjects: Geography
Urban and Regional Planning not elsewhere classified

description: Supplemental Material for A hybrid modeling approach considering spatial heterogeneity and nonlinearity to discover the transition rules of Urban cellular automata models by Haoran Zeng, Bin Zhang and Haijun Wang in Environment and Planning B: Urban Analytics and City Science.
Additional file 2 of Stakeholder development of an implementation strategy for fall prevention in Norwegian home care – a qualitative co-creation approach
Creators: name: Linnerud, Siv
name: Kvael, Linda Aimee Hartford
name: Graverholt, Birgitte
name: Idland, Gro
name: Taraldsen, Kristin
name: Brovold, Therese
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 2
Associations Between Neighborhood Park Access and Longitudinal Change in Cognition in Older Adults: The Multi-Ethnic Study of Atherosclerosis.
Creators: name: Kaufman, Joel D
name: Fitzpatrick, Annette L
name: Galvin, James E
name: Hirsch, Jana A
name: Chang, Lun-Ching
name: Heckbert, Susan R
name: Rapp, Stephen R
name: Evenson, Kelly R
name: Besser, Lilah M
name: Hughes, Timothy M
name: Michael, Yvonne L
Publisher: name: IOS Press
Year: 2021

description: BACKGROUND: Preliminary evidence suggests associations between neighborhood park access and better late-life cognition and reduced Alzheimer's disease (AD) risk. OBJECTIVE: Examine associations between neighborhood park access and longitudinal change in cognition among U.S. older adults without dementia. METHODS: We used 2000-2018 observational data from the population-based, multi-site Multi-Ethnic Study of Atherosclerosis (n€Š=€Š1,733). Measures included proportion of neighborhood park space (park access), distance to nearest park, and 6-year dichotomous and continuous change in scores on the Cognitive Abilities Screening Instrument (CASI; global cognition) and Digit Symbol Coding task (processing speed). Multivariable random intercept models tested main associations and mediation by depressive symptoms, physical activity, and PM2.5 exposure. Effect modification by race (African Americans/Blacks versus Whites) was tested using interaction terms. RESULTS: Greater park access (equivalent to 10%more in 1/2-mile around home) was associated with maintained/improved CASI score over six years independent of several covariates including individual- and neighborhood-level socioeconomic status (Odds ratio: 1.04; 95%confidence interval: 1.00-1.08). No other associations were observed with the dichotomous or continuous measures of cognitive change and no mediators were found. While a borderline association was seen between greater park access and maintained/improved CASI for African Americans/Blacks but not for Whites, effect modification was not confirmed by testing interaction terms. CONCLUSION: Neighborhood park access may help maintain/improve late-life global cognition. However, our findings need replication in other population-based studies and regions. Additionally, studies are needed to determine if associations between park access and change in cognition vary by race/ethnicity to inform intervention efforts.
Speculative Co-design: a framework for enhancing the usability of medical devices through iterative, speculative, collaboration with medical device recipients.
Creators: name: ROWAN CHRISTOPHER PAGE
Publisher: name: Monash University
Year: 2018
Subjects: subject: 90304 Medical Devices
subject: FOS: Medical engineering
subject: Design

description: Use errors are the leading cause of failures with medical devices. This thesis examines how contemporary methods of industrial design research, and practice, can better include users in the medical device design process. This collaborative process uncovers information about how these devices will be used, through investigative prototyping practices. These practices encourage collaborative speculation on the future of devices, within the early formative stages of research and development. These methods are applied and evaluated through a series of design projects in collaboration with medical device manufacturer Cochlear Limited.
sj-pdf-1-ppo-10.1177_07439156221145696 - Supplemental material for Celebrate Good Times: How Celebrations Increase Perceived Social Support
Creators: name: Brick, Danielle J.
name: Wight, Kelley Gullo
name: Bettman, James R.
name: Chartrand, Tanya L.
name: Fitzsimons, Gavan J.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 150402 Hospitality Management
subject: FOS: Economics and business

description: Supplemental material, sj-pdf-1-ppo-10.1177_07439156221145696 for Celebrate Good Times: How Celebrations Increase Perceived Social Support by Danielle J. Brick, Kelley Gullo Wight, James R. Bettman, Tanya L. Chartrand and Gavan J. Fitzsimons in Journal of Public Policy & Marketing
66218: Letter: To Marion Scott.
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Includes 'For England' / 'February Day'. | File description(s):Envelope containing poems.
Includes 'For England' / 'February Day'.
COMPORTEMENTS FINANCIERS DES PME FAMILIALES MAROCAINES : ESSAI D’ANALYSE
Creators: name: KARIM, Khaddouj
Publisher: name: Revue Economie, Gestion et Société
Year: 2016
Subjects: Family SMC, financial behaviors

description: La petite et moyenne entreprise (PME) est considérée aujourd’hui comme l’une des solutions pour le développement économique et social du Maroc. Un ensemble de programme a été mis en place afin d’assurer un environnement propice à son développement. Toutefois, la recherche portant sur cette catégorie d’entreprise est encore à ses débuts. L’objectif de ce travail est de vérifier si les comportements financiers des PME familiales marocaines sont spécifiques. La vérification de notre hypothèse a nécessité l'utilisation d'une enquête et son analyse, ce qui a permis de mieux cerner et identifier les spécificités financières de ce type d'entreprise et ses implications.
description: Revue Economie, Gestion et Société, No 6 (2016)
sj-docx-1-msc-10.1177_09691413221144382 - Supplemental material for Test accuracy of artificial intelligence-based grading of fundus images in diabetic retinopathy screening: A systematic review
Creators: name: Zhelev, Zhivko
name: Peters, Jaime
name: Rogers, Morwenna
name: Allen, Michael
name: Kijauskaite, Goda
name: Seedat, Farah
name: Wilkinson, Elizabeth
name: Hyde, Christopher
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111402 Obstetrics and Gynaecology
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-msc-10.1177_09691413221144382 for Test accuracy of artificial intelligence-based grading of fundus images in diabetic retinopathy screening: A systematic review by Zhivko Zhelev, Jaime Peters, Morwenna Rogers, Michael Allen, Goda Kijauskaite, Farah Seedat, Elizabeth Wilkinson and Christopher Hyde in Journal of Medical Screening