cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Phytochemical analysis and in vitro assessment of Polystichum setiferum extracts for their cytotoxic and antimicrobial activities
Creators: name: Şuţan, Nicoleta Anca
name: Fierăscu, Irina
name: Fierăscu, Radu
name: Ionica, Deliu
name: Soare, Liliana Cristina
Publisher: name: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics
Year: 2019

description: Ferns are traditionally used by some nations to treat rheumatism, lungs, gynecology, blood and digestion dysfunctions, and several others illnesses. The present study evaluates the bioactivity of methanol and ethanol extracts from Polystichum setiferum (Forssk.) Moore ex Woyn. in an Allium cepa test and disk diffusion test. In the Allium cepa test the methanol and ethanol extracts induced a significant time-related increase in the mitotic index. The tested extracts were non-mutagenic by used assay, with no occurrence either the structural or numerical aberrations detected. The extracts were also evaluated in terms of trace elements (by EDXRF) and qualitative composition (by UV-VIS, FTIR and total phenolic content). In the disk diffusion test, methanol extracts from leaves determined a small inhibition of bacterial growth for Enterobacter cloacae and Citrobacter freundii strains relatively to control sample (methanol). The ethanol extracts were more efficient, the diameter of inhibition growth zones measured from 7 to 10 mm, the most affected strain was Chryseobacterium meningosepticum.
description: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics, V. 72 N. 2 (2019)
Fluorescence In Situ Hybridisation Study of Micronuclei in C3A Cells Following Exposure to ELF-Magnetic Fields
Creators: name: Verschaeve, Luc
name: Antonissen, Roel
name: Baeyens, Ans
name: Vral, Anne
name: Maes, Annemarie
Publisher: name: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics
Year: 2019

description: Human C3A cells were exposed to extremely low frequency (50 Hz) magnetic fields (ELF-MF’s) up to 500 µT. They were subjected to the micronucleus assay using a Fluorescence In Situ Hybridization (FISH) technique with an in-house pan-centromere probe. We found no increased frequency in micronucleated cells and no change in the proportion of centromere positive over centromere negative micronuclei compared to the unexposed control cells. These results are in accordance with some, but in contradiction with other previously published investigations underlining that effects of environmental ELF-EMF’s on cellular DNA may be very subtle and that small changes or environmental influences may determine the outcome of a (geno)toxicity study. Interestingly, a low-level (5µT) exposure resulted in less than the background micronucleus frequency.
description: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics, V. 72 N. 2 (2019)
Insights into the Possible Mechanisms By Which Platelet-Activating Factor and PAF-receptors Function in Vascular Smooth Muscle in Magnesium Deficiency and Vascular Remodeling: Possible Links to Atherogenesis, Hypertension and Cardiac Failure
Creators: name: SciDoc Publishers International Journal Of Cardiology And Research (IJCRR)
name: Altura BM
name: Shah NC
name: Gatha J. Shah
name: Pérez-Abela JL
name: Altura BT
Publisher: name: figshare
Year: 2017
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Platelet-activating factor (PAF) is a phospholipid mediator and cell signaling molecule which displays multiple biological and pathophysiological attributes, running the gamut from inflammation to cell differentiation and proliferation [1-4]. As is well-known, PAF interacts with specific membrane PAF-receptors (PAF-Rs) to initiate all cellular responses via specific G-proteincoupled receptors [1-4]. Although these initiated membrane receptor phenomena are mostly established for several tissuecell systems [1-8], exactly how PAF and PAF-Rs cause vascular remodeling in hypertension and atherosclerosis is not clear. A little more than 15 years ago, PAF was identified as a molecule that stimulated activation of nuclear factor-kappaB (NF-kB)
Identification of Differentially Methylated Markers among Cytogenetic Risk Groups of Acute Myeloid Leukemia
Creators: name: Qu, Xiaoyu
name: Davison, Jerry
name: Du, Liping
name: Storer, Barry
name: L Stirewalt, Derek
name: Heimfeld, Shelly
name: Estey, Elihu
name: R Appelbaum, Frederick
name: Fang, Min
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: Cancer
subject: Biological Sciences
subject: Earth and Environmental Sciences
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology

description: ABSTRACTAberrant DNA methylation is known to occur in cancer, including hematological malignancies such as acute myeloid leukemia (AML). However, less is known about whether specific methylation profiles characterize specific subcategories of AML. We examined this issue by using comprehensive high-throughput array-based relative methylation analysis (CHARM) to compare methylation profiles among patients in different AML cytogenetic risk groups. We found distinct profiles in each group, with the high-risk group showing overall increased methylation compared with low- and mid-risk groups. The differentially methylated regions (DMRs) distinguishing cytogenetic risk groups of AML were enriched in the CpG island shores. Specific risk-group associated DMRs were located near genes previously known to play a role in AML or other malignancies, such as MN1, UHRF1, HOXB3, and HOXB4, as well as TRIM71, the function of which in cancer is not well characterized. These findings were verified by quantitative bisulfite pyrosequencing and by comparison with results available at the TCGA cancer genome browser. To explore the potential biological significance of the observed methylation changes, we correlated our findings with gene expression data available through the TCGA database. The results showed that decreased methylation at HOXB3 and HOXB4 was associated with increased gene expression of both HOXB genes specific to the mid-risk AML, while increased DNA methylation at DCC distinctive to the high-risk AML was associated with increased gene expression. Our results suggest that the differential impact of cytogenetic changes on AML prognosis may, in part, be mediated by changes in methylation.
Insights on cytogenetic of the only strict African representative of genus Prunus (P. africana): first genome size assessment, heterochromatin and rDNA chromosome pattern
Creators: name: Nzweundji, Justine Germo
name: Ngo Ngwe, Marie Florence Sandrine
name: Siljak-Yakovlev, Sonja
Publisher: name: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics
Year: 2019

description: Prunus africana is a multipurpose evergreen species endemic to Africa and an endangered species because of overexploitation. The great importance of this species resides particularly in the use of its bark against benign prostatic hyperplasia. As for most tropical trees and generally woody species, cytogenetic studies are scarce. Standard and molecular cytogenetic approaches have been implemented for the first time to study P. africana from Cameroon. This is the tetraploid species with a chromosome number of 2n=4x=32. Genome size estimated by flow cytometry was 2C=1.44 pg. Five loci (ten signals) of 35S rRNA genes were observed after fluorescence in situ hybridization. Ten G-C rich DNA regions were detected by chromomycin A3 fluorochrome banding. All chromomycin positive bands were co-localized with 35 S rDNA signals. Prunus africana, the only strict African representative of genus Prunus, is in need of the conservation strategy and in situ management that we are also discussing in this work.
description: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics, V. 72 N. 2 (2019)
Myocarditis Related to Rhinovirus
Creators: name: SciDoc Publishers International Journal Of Cardiology And Research (IJCRR)
Publisher: name: figshare
Year: 2017
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Myocarditis has been defined by the World Health Organization/ International Society and Federation of Cardiology as an inflammatory disease of the heart muscle diagnosed by established histological, immunologic, and immunohistological criteria [4]. It is a rare disease with the rate 0.5 patient per 10000 cases at the clinic [1]. It is caused primarily by numerous infectious agents, but it may also accompany autoimmune disease, hypersensitivity reactions, and toxins [2]. The core principles of treatment in myocarditis are optimal care of arrhythmia and of heart failure and, where supported by evidence, etiology-targeted therapy
Karyotypic description and repetitive DNA chromosome mapping of Melipona interrupta Latreille, 1811 (Hymenoptera: Meliponini)
Creators: name: Travenzoli, Natália Martins
name: Barbosa, Ingrid Cândido De Oliveira
name: Carvalho-Zilse, Gislene Almeida
name: Salomão, Tânia Maria Fernandes
name: Lopes, Denilce Meneses
Publisher: name: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics
Year: 2019

description: Heterochromatic patterns in the genus Melipona vary among subgenera species. Melikerria is the only subgenus that presents species with different content of heterochromatin. Thus, the cytogenetic knowledge of other species of this subgenus is important for the understanding of karyotype evolution in Melipona. Here, we describe the karyotype of Melipona (Melikerria) interrupta based on the chromosomal heterochromatic patterns, AT and GC richness, mapping sequences of rDNA, microsatellites and telomeric regions. We observed 2n=18 chromosomes, with a high heterochromatin content rich in AT and euchromatic regions rich in GC base pairs. The high GC content was observed at interstitial region near the junction of the stained euchromatin and heterochromatin of the first chromosomal pair, the same region marked for the rDNA 18S locus. Microsatellites hybridized only on euchromatin regions and the telomeric probe on terminal regions of all chromosomes. Melipona (Melikerria) interrupta belongs to previous described heterochromatic Group II, suggesting there has been an increase in heterochromatin content in Melikerria. The M. quinquefasciata, belonging to the same subgenus as Melipona (Melikerria) interrupta, has low content of heterochromatin and appears to be evolving independently. So, the differences in the content heterochromatin, in the marker regions of CMA3 and the rDNA 18S locus in species of Melikerria is an important feature to be investigated further.
description: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics, V. 72 N. 2 (2019)
Differences in C-band patterns between the Japanese house mice (Mus musculus) in Hokkaido and eastern Honshu
Creators: name: Myoshu, Hikari
name: Iwasa, Masahiro A.
Publisher: name: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics
Year: 2019

description: We characterized and categorized the C-band patterns of the house mouse Mus musculus from four areas in Hokkaido and Honshu of the Japanese Islands as a biparental marker. The C-band patterns are categorized as polymorphic, monomorphic, or intermediate, corresponding to those of the Korean mice, C57BL/6, and F1 hybrid mice bred from the Japanese mice and a laboratory mouse, respectively. The C-band patterns mainly differ between mice from Hokkaido and Honshu. The polymorphic patterns are shown in mice in Honshu, while the intermediate patterns are shown in mice in Hokkaido, with an exceptional case of a monomorphic pattern found in one locality. In the other localities of Hokkaido and northeastern Honshu, the C-band patterns are not congruent with an estimation by maternal element in our previous study, whereas the congruence is observed in other localities. It is suggested that the characteristics of the Japanese house mice have been formed through complicated processes by different expansions between biparental and maternal elements.
description: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics, V. 72 N. 2 (2019)
title: Evolution from subduction initiation to mature island arc volcanism in the Upper Eocene to Middle Miocene Vitiaz Arc, SW Pacific: Evidence from Malekula Island (Vanuatu)
Creators: name:  Schneider ,   Kathrin P
name:  Haase ,   Karsten M
name:  Pelletier ,   Bernard
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: The oldest volcanic rocks exposed on Malekula Island, now belonging to the New Hebrides Island Arc, formed in the Upper Eocene to Middle Miocene Vitiaz Island Arc, Southwest Pacific. They are thought to have formed contemporaneously with Fiji and the Izu-Bonin-Mariana (IBM) arc during westward subduction initiation of the Pacific beneath the Indo-Australian Plate [e.g., 1]. To test this hypothesis with regard to the mantle source compositions and contributions from the subducting slab, we provide major- and trace element data combined with Hf, Nd, and Pb isotopes for twenty-seven volcanic rocks of Malekula Island. Our results show that Malekula lavas display similar magma types, i.e., boninite-series rocks, island arc basalts, and MORB-type tholeiites, to the earliest volcanic rocks of Fiji and the IBM arc resembling the sequential stratigraphy of the IBM system [2], rather than the interlayered stratigraphy of early arc rocks on Fiji [3]. Moreover, Malekula lavas display a change in Hf-Nd isotope composition from isotopically ‘Indian’, similar to the IBM arc [4, 5], to mainly ‘Pacific’, like on Fiji [3]. We interpret this progressive change in mantle source composition to reflect the propagation of ‘Pacific’ South Fiji Basin spreading into the Vitiaz Arc. Hence, the Malekula lava succession provides a link between subduction initiation in the Northwest and Southwest Pacific. [1] Hall (2002) J Asian Earth Sci 20. [2] Ishizuka et al. (2011) EPSL 306. [3] Todd et al. (2012) EPSL 335-336. [4] Reagan et al. (2010) G311(3). [5] Li et al. (2019) EPSL 518.
Mindfulness and Emotion Regulation: Insights from Neurobiological, Psychological, and Clinical Studies
Creators: name: Guendelman, Simón
name: Medeiros, Sebastián
name: Rampes, Hagen
Publisher: name: Humboldt-Universität zu Berlin
Year: 2017
Subjects: subject: mindfulness
subject: emotion regulation
subject: neuroimaging
subject: top down and bottom up processing
subject: emotion dysregulation disorders
subject: embodied cognition
subject: 150 Psychologie

description: There is increasing interest in the beneficial clinical effects of mindfulness-based interventions (MBIs). Research has demonstrated their efficacy in a wide range of psychological conditions characterized by emotion dysregulation. Neuroimaging studies have evidenced functional and structural changes in a myriad of brain regions mainly involved in attention systems, emotion regulation, and self-referential processing. In this article we review studies on psychological and neurobiological correlates across different empirically derived models of research, including dispositional mindfulness, mindfulness induction, MBIs, and expert meditators in relation to emotion regulation. From the perspective of recent findings in the neuroscience of emotion regulation, we discuss the interplay of top-down and bottom-up emotion regulation mechanisms associated with different mindfulness models. From a phenomenological and cognitive perspective, authors have argued that mindfulness elicits a “mindful emotion regulation” strategy; however, from a clinical perspective, this construct has not been properly differentiated from other strategies and interventions within MBIs. In this context we propose the distinction between top-down and bottom-up mindfulness based emotion regulation strategies. Furthermore, we propose an embodied emotion regulation framework as a multilevel approach for understanding psychobiological changes due to mindfulness meditation regarding its effect on emotion regulation. Finally, based on clinical neuroscientific evidence on mindfulness, we open perspectives and dialogues regarding commonalities and differences between MBIs and other psychotherapeutic strategies for emotion regulation.
EarthChem - FAIR data for geochemistry, volcanology, and petrology
Creators: name: Lehnert, Kerstin
Publisher: name: Zenodo
Year: 2023

description: Presentation on the operation and services of the EarthChem Data System at the Open Data in Geochemistry Part 1: Navigating the Present Data Infrastructure Landscape virtual workshop hosted during the Goldschmidt 2023 conference.
Telomeric heterochromatin and meiotic recombination in three species of Coleoptera (Dorcadion olympicum Ganglebauer, Stephanorrhina princeps Oberthür and Macraspis tristis Laporte)
Creators: name: Dutrillaux, Anne-Marie
name: Dutrillaux, Bernard
Publisher: name: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics
Year: 2019

description: Centromeres are generally embedded in heterochromatin, which is assumed to have a negative impact on meiotic recombination in adjacent regions, a condition required for the correct segregation of chromosomes at anaphase I. At difference, telomeric and interstitial regions rarely harbour large heterochromatic fragments. We observed the presence at the heterozygote status of heterochromatin in telomere region of some chromosomes in 3 species of Coleoptera: Dorcadion olympicum; Stephanorrhina princeps and Macraspis tristis. This provided us with the opportunity to study the relationship between heterochromatin, chiasma location and meiotic recombination independently from the proximity of centromeres in this order of insects. In acrocentric chromosomes, the presence of heterochromatin in telomere region of the long arm displaces recombination near the centromere. In sub-metacentrics, recombination is almost always restricted to the other arm. This at distance effect of heterochromatin may deeply influence genetic drift.
description: Caryologia. International Journal of Cytology, Cytosystematics and Cytogenetics, V. 72 N. 2 (2019)
Molecular interactions of the Saccharomyces cerevisiae Atg1 complex provide insights into assembly and regulatory mechanisms
Creators: name: Lu, Shan
name: Liu, Xu
name: Dong, Meng-Qiu
name: H Chew, Leon
name: Kk Li, Franco
name: Yh Yu, Angela
name: J Klionsky, Daniel
name: K Yip, Calvin
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Chemistry
subject: Earth and Environmental Sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Microbiology
subject: Biochemistry
subject: Biophysics

description: The Atg1 complex, which contains 5 major subunits: Atg1, Atg13, Atg17, Atg29, and Atg31, regulates the induction of autophagy and autophagosome formation. To gain a better understanding of the overall architecture and assembly mechanism of this essential autophagy regulatory complex, we have reconstituted a core assembly of the Saccharomyces cerevisiae Atg1 complex composed of full-length Atg17, Atg29, and Atg31, along with the C-terminal domains of Atg1 (Atg1[CTD]) and Atg13 (Atg13[CTD]). Using chemical-crosslinking coupled with mass spectrometry (CXMS) analysis we systematically mapped the intersubunit interaction interfaces within this complex. Our data revealed that the intrinsically unstructured C-terminal domain of Atg29 interacts directly with Atg17, whereas Atg17 interacts with Atg13 in 2 distinct intrinsically unstructured regions, including a previously unknown motif that encompasses several putative phosphorylation sites. The Atg1[CTD] crosslinks exclusively to the Atg13[CTD] and does not appear to make direct contact with the Atg17-Atg31-Atg29 scaffold. Finally, single-particle electron microscopy analysis revealed that both the Atg13[CTD] and Atg1[CTD] localize to the tip regions of Atg17-Atg31-Atg29 and do not alter the distinct curvature of this scaffolding subcomplex. This work provides a comprehensive understanding of the subunit interactions in the fully assembled Atg1 core complex, and uncovers the potential role of intrinsically disordered regions in regulating complex integrity.
Unprotected Distal LMCA Angioplasty with Simulataneous Kissing Stent (SKS) Technique in Left Dominant Coronary Circulation: A Nightmare for Interventionist
Creators: name: SciDoc Publishers International Journal Of Cardiology And Research (IJCRR)
name: H.S. Natraj Setty
name: T .R .Raghu
name: Kharge, Jayashree
name: B.K. Geetha, Veeresh Patil Hebbal
name: Shivananda Patil
name: C. N. Manjunath
Publisher: name: figshare
Year: 2017
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Left main coronary artery stenosis is the most challenging lesion in patients with acute coronary syndromes. Since the amount of myocardium at risk is very high, the patient is often in cardiogenic shock, and the risk of death is high and even more so in left dominant coronary system. Left main stenosis is a Class I indication for CABG -ACC/AHA guidelines and has been a relative contraindication to PCI. We report an elderly patient presenting with ACS with ECG showing ST elevation in lead a VR. Coronary angiogram revealed left dominant system with left main stenosis and ostioproximal LAD and LCX disease. Double stenting of the unprotected left main with bifurcation disease done with SKS technique with simultaneous stenting and post balloon dilatation was done with good results. Current guidelines still indicate CABG as optimal treatment for LMCA lesions. The choice of stenting technique for LMCA bifurcations should be based on bifurcation morphology.
title: Underground Hydrogen Storage (UHS) – status quo and perspectives in Germany
Creators: name:  Warnecke ,   Matthias
name:  Röhling ,   Simone
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Bundesanstalt für Geowissenschaften und Rohstoffe (BGR), Germany(1);Recently, politics and industry has discussed green hydrogen as one of the carbon-zero energy sources of the future. Besides many other countries, Germany formulates clear goals for the energy transition from fossil to hydrogen energy in its "National Hydrogen Strategy". In order to ensure steady supply of hydrogen and to secure national reserves the underground storage of hydrogen (UHS) is increasingly coming into focus. Germany already has extensive experience in storing natural gas to cover supply shortages in the medium term, which follows same geologic principles as for hydrogen. In general, there are two main underground storage options for hydrogen. While in caverns such as salt-caverns operating UHS localities already exist, hydrogen storage facilities in porous media like aquifers or depleted gas reservoirs are still unrealized. In recent studies such as InSpEE and INSPEE-DS, the Federal Institute for Geoscience and Resources (BGR) provided a sound database of potential salt structures and salt horizons that could be used for UHS. This study gives an overview over the research made within all known types of underground hydrogen storage and discusses each their potential in Germany.
Molecular interactions of the Saccharomyces cerevisiae Atg1 complex provide insights into assembly and regulatory mechanisms
Creators: name: Lu, Shan
name: Liu, Xu
name: Dong, Meng-Qiu
name: H Chew, Leon
name: Kk Li, Franco
name: Yh Yu, Angela
name: J Klionsky, Daniel
name: K Yip, Calvin
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Chemistry
subject: Earth and Environmental Sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Microbiology
subject: Biochemistry
subject: Biophysics

description: The Atg1 complex, which contains 5 major subunits: Atg1, Atg13, Atg17, Atg29, and Atg31, regulates the induction of autophagy and autophagosome formation. To gain a better understanding of the overall architecture and assembly mechanism of this essential autophagy regulatory complex, we have reconstituted a core assembly of the Saccharomyces cerevisiae Atg1 complex composed of full-length Atg17, Atg29, and Atg31, along with the C-terminal domains of Atg1 (Atg1[CTD]) and Atg13 (Atg13[CTD]). Using chemical-crosslinking coupled with mass spectrometry (CXMS) analysis we systematically mapped the intersubunit interaction interfaces within this complex. Our data revealed that the intrinsically unstructured C-terminal domain of Atg29 interacts directly with Atg17, whereas Atg17 interacts with Atg13 in 2 distinct intrinsically unstructured regions, including a previously unknown motif that encompasses several putative phosphorylation sites. The Atg1[CTD] crosslinks exclusively to the Atg13[CTD] and does not appear to make direct contact with the Atg17-Atg31-Atg29 scaffold. Finally, single-particle electron microscopy analysis revealed that both the Atg13[CTD] and Atg1[CTD] localize to the tip regions of Atg17-Atg31-Atg29 and do not alter the distinct curvature of this scaffolding subcomplex. This work provides a comprehensive understanding of the subunit interactions in the fully assembled Atg1 core complex, and uncovers the potential role of intrinsically disordered regions in regulating complex integrity.
title: On GPS-IR technique for measuring shallow sediment compaction
Creators: name:  Karegar,   Makan
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Institute of Geodesy and Geoinformation, University of Bonn, Germany(1);The solid Earth aspects of relative sea-level change can dominate in low-lying coastal areas with potentially vulnerable to accelerating rates of sea-level rise. Global Positioning System (GPS) as companion tools to tide gauges allow long-term assessment of solid Earth deformation, thus essential for disclosing climate-forced mechanisms contributing to sea-level rise (SLR). So far, it has not been possible to measure shallow displacements that occur above the base of GPS monument because conventional positioning determines the vertical component of position changes resulting from displacements occurring beneath the foundation. We use an emerging technique, GPS interferometric reflectometry (GPS-IR), to estimate the rate of this process in two coastal regions with thick Holocene deposits, the Mississippi Delta and the eastern margin of the North Sea. We show that the rate of land motion from shallow compaction is comparable to or larger than the rate of SLR. Since many of the world's great coastal cities are built on river deltas with comparable Holocene sections, our results suggest that estimates of flood risk and land loss have been underestimated. We demonstrate environmental impact of parking lots and streets surrounding a monitoring site on GPS measurements. Such kinematic environments will perturb the amplitude of reflected signals to GPS sensors and thus leave time-variable imprints on GPS observations. Thus, obtaining desirable reflections for shallow subsidence monitoring could be challenging.
OA eBook Usage (OAeBU) Metadata Community Consultation
Creators: name: Neylon, Cameron
Publisher: name: Zenodo
Year: 2021
Subjects: open access
books
usage

description: This community consultation document was shared via social media, communities of practices, and project listservs to solicit OA book stakeholder feedback on issues identified through data ingest and matching proof of concept processes developed for the OAeBU Data Trust project’s dashboard pilot partnerships with four global university presses, a commercial press, and a publishing platform. Consultation was sought on issues related to how linked book metadata should be used for book disambiguation, for linking specific book-related file URLs to the concept of a specific book, indication of open access status, and usage data granularity (e.g. chapter vs book level).
description: This work was made possible through grant funding provided via the "Developing a Data Trust for Open Access Ebook Usage" project funded by The Andrew W. Mellon Foundation.
ОПРЕДЕЛЕНИЕ И СТРУКТУРА ПРОСТОГО ПРЕДЛОЖЕНИЯ: ОСНОВНЫЕ ЭЛЕМЕНТЫ И ИХ ФУНКЦИИ
Creators: name: Икболжонова, Сабрина
name: Исаева, Зера
Publisher: name: Zenodo
Year: 2025

description: В данной статье исследуется понятие и структура простого предложения как одной из базовых единиц синтаксиса. Приводится определение простого предложения, подчёркивается его роль в построении осмысленных и завершённых высказываний. Основное внимание уделяется грамматической основе, состоящей из подлежащего и сказуемого, а также функциям второстепенных членов — дополнений, определений и обстоятельств. Рассматриваются структурные особенности и синтаксические связи между элементами предложения. Освещаются классификации простых предложений по различным критериям: по цели высказывания, интонации и составу. Особый акцент делается на анализе функций каждого элемента в передаче смысла и логической завершённости высказывания.
Takotsubo Syndrome Triggered by Acute Coronary Syndrome in a Cohort of 20 Patients: An often Missed Diagnosis
Creators: name: SciDoc Publishers International Journal Of Cardiology And Research (IJCRR)
name: Y-Hassan S
Publisher: name: figshare
Year: 2017
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Background: In spite of being a major stress factor, acute coronary syndrome (ACS) is still regarded as an exclusion criterion for takotsubo syndrome (TS). The aim of the study is to find out an association between ACS, post-ischemic myocardial stunning (PIMS) and TS. Methods: A series of twenty patients with ACS having an acute coronary culprit lesion on coronary angiography and signs of left ventricular dysfunction, which extended beyond the supply region of the diseased coronary artery were studied. Results: Thirteen (65%) out of the 20 patients were women. Ages ranged from 37 to 85 years old. All patients had signs consistent with PIMS. The extent of the stunned myocardium in all patients went beyond the supply region of the diseased coronary artery. The left ventricular myocardial stunning had also a peculiar ballooning appearance during systole, a clinical picture and course also consistent with TS. In all patients, there was no evidence of any emotional or physical stress factor apart from the ACS event. Conclusions: PIMS induced by ACS had typical feature of TS suggesting that PIMS and TS may be two (among other) different names for the same acute cardiac clinical condition. ACS may trigger rather than exclude TS.
Iatrogenic Right Sided Infective Endocarditis in Children with CHD
Creators: name: SciDoc Publishers International Journal Of Cardiology And Research (IJCRR)
name: H.S.Natraj Setty
name: Vijayalakshmi IB
name: Narasimhan C
name: Manjunath CN
Publisher: name: figshare
Year: 2017
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Background: Right sided endocarditis (IE) occurs predominantly in intravenous drug abusers, and occasionally acquired in hospital as a result of contaminated intravascular devices. The iatrogenic IE of tricuspid valve in children treated with intravenous (IV) injections for various unrelated conditions is not reported in literature. Objective: Aim is to report clinical outcome, microbiological and echocardiographic presentation of iatrogenic right sided IE in 4 children. Materials and methods: In a span of 3 months four children, age ranging from 1 month to 5 years, three females and one male, who presented with prolonged history of fever formed the material for this study. Two cases had ventricular septal defect (VSD), one had a small atrial septal defect (ASD) and one patient had tetralogy of Fallot (TOF). The blood culture grew coagulase negative staphylococcus in two patients and gram negative bacilli in the one month infant. The diagnosis of tricuspid valve endocarditis was established by transthoracic echocardiography (TTE) in all the four patients. In addition to vegetation on tricuspid valve, the vegetation was also detected in inferior vena cava (IVC) in one case and in another case a large vegetation was seen closing the VSD. Discussion: Right sided endocarditis accounts for only 5 - 10% of cases of IE. It has been estimated that up to 76% of cases of endocarditis among IV drug abusers involve the right heart, compared with only 9% in non-addict patients. The bacterial endocarditis is extremely rare in cases of ASD and TOF. This series of four cases is notable for the iatrogenic IE of tricuspid valve in children treated in the reputed hospitals with IV injections and IV fluids for various unrelated non cardiac conditions. The infection in this series occurred upon previously normal tricuspid valve. Three patients died (75%) and only one survived. Conclusions: Right sided endocarditis can occur in CHD patients when proper aseptic precautions are not taken while treating with IV injections. The blood culture and TTE play an important role in diagnosis and management of right sided IE.
title: Automated heavy mineral analysis of silt-sized sediment by artificial-intelligence guided Raman Spectroscopy
Creators: name:  Lünsdorf ,   Nils Keno
name:  Lünsdorf ,   Jan Ontje
name:  Újvári ,   Gábor
name:  von Eynatten ,   Hilmar
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Compositional data on heavy minerals is fundamental in sedimentary provenance analysis. Typically, this data is gathered by optical microscopy and more recently, by mineral chemical analysis (MLA, QEMSCAN) or Raman micro-spectroscopy. In silt-sized sediments optical microscopy is unfeasible. We introduce a systematic and highly efficient approach to assess the heavy mineral composition in fine grain-size fractions (10-30 µm and 30-62 µm) by Raman micro-spectroscopy. The approach starts with a web-application that creates and visualizes large mosaic images from which arbitrary objects can be selected for training and inference of a region-based convolutional neural network (R-CNN). Here, mineral grains are automatically selected by passing the tiles of a mosaic image of the sample slide into the R-CNN. For each detected grain a polygon is computed from which positional and optical parameters are derived. Using this polygon data, the measurement parameters at the Raman spectrometer are individually set to account for varying Raman scattering intensities and irradiation resistivity. After the compositional data is obtained, Raman spectra are evaluated and further single-grain geochemical methods (ICPMS, EMPA) can be applied to the identified and referenced grains (e.g. U-Pb dating of zircon). The method was tested on 13 samples from three loess profiles from Germany and Hungary. About 100.000 minerals were analyzed and provenance signals demonstrate clear contrasts between the sections. Being automated, this approach allows for analyzing large sample numbers with higher precision (i.e. counting statistics) on silt-sized materials, thus opening new avenues in sedimentary provenance analysis.
The Correlation between the Plasma Level of NT-Pro BNP and Left Ventricular Diastolic Dysfunction
Creators: name: SciDoc Publishers International Journal Of Cardiology And Research (IJCRR)
name: Arafa, Osama Sanad
name: Hamouda, Mohamed Ahmed
name: Elian, Mohamed Abd El-Kader
name: Mostafa, Shaimaa Ahmed
name: Mahmoud, Mahmoud Said
Publisher: name: figshare
Year: 2017
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Objective: To study the correlation between plasma level of N-terminal pro-BNP and left ventricular diastolic dysfunction in asymptomatic patients. Methods: The study included 35 patients divided into control group: included 10 patients with normal systolic and diastolic function and patient group: included 25 patients with normal systolic and asymptomatic diastolic dysfunction. The patients were evaluated by conventional echocardiography (diameters, systolic and diastolic function) and tissue Doppler (early diastolic velocity) then E/e` was measured. Serum pro BNP was measured and correlated with demographic and echocardiographic parameters and its sensitivity, specificity were evaluated. Results: Both groups were of comparable age, gender, BMI, risk factors and systolic function. By Doppler echocardiography there was no difference in E velocity between two groups (0.64+0.18 m/sec Vs 0.67+0.14 P = 0.302), but by tissue Doppler there was significant difference in the mean value of e` velocity (m/sec) (0.14+0.06 Vs 0.06+0.01 P=0.001) and E/eˋ (5.03+0.149 Vs 0.55+1.79 P= 0.001). There was significant difference between two groups according to serum NT pro BNP (ng/ml) was (59.1) in the control group Vs (154.1) in patient group (P = 0.001). There was significant correlation between serum NT pro BNP and E (P= 0.001) and E/e` (P = 0.001). The sensitivity of serum NT Pro BNP was 94.2, specificity was 88.1, positive predictive value was 90.6 and its accuracy was 86.2. Conclusion: Serum level of NT pro BNP can be used as innovative method in predicting asymptomatic diastolic dysfunction and so prevent the progression to symptomatic diastolic heart failure.
Decomposing Self-Control: Individual Differences in Goal Pursuit Despite Interfering Aversion, Temptation, and Distraction
Creators: name: Steimke, Rosa
name: Stelzel, Christine
name: Gaschler, Robert
name: Rothkirch, Marcus
name: Ludwig, Vera U.
name: Paschke, Lena M.
name: Trempler, Ima
name: Kathmann, Norbert
name: Goschke, Thomas
name: Walter, Henrik
Publisher: name: Humboldt-Universität zu Berlin
Year: 2016
Subjects: subject: eyetracking
subject: visual attention
subject: disgusting pictures
subject: erotic pictures
subject: self-control task
subject: willpower
subject: 150 Psychologie

description: Self-control can be defined as the ability to exert control over ones impulses. Currently, most research in the area relies on self-report. Focusing on attentional control processes involved in self-control, we modified a spatial selective attentional cueing task to test three domains of self-control experimentally in one task using aversive, tempting, and neutral picture-distractors. The aims of the study were (1) to investigate individual differences in the susceptibility to aversive, tempting, and neutral distraction within one paradigm and (2) to test the association of these three self-control domains to conventional measures of self-control including self-report. The final sample consisted of 116 participants. The task required participants to identify target letters “E” or “F” presented at a cued target location while the distractors were presented. Behavioral and eyetracking data were obtained during the performance of the task. High task performance was encouraged via monetary incentives. In addition to the attentional self-control task, self-reported self-control was assessed and participants performed a color Stroop task, an unsolvable anagram task and a delay of gratification task using chocolate sweets. We found that aversion, temptation, and neutral distraction were associated with significantly increased error rates, reaction times and gaze pattern deviations. Overall task performance on our task correlated with self-reported self-control ability. Measures of aversion, temptation, and distraction showed moderate split-half reliability, but did not correlate with each other across participants. Additionally, participants who made a self-controlled decision in the delay of gratification task were less distracted by temptations in our task than participants who made an impulsive choice. Our individual differences analyses suggest that (1) the ability to endure aversion, resist temptations and ignore neutral distractions are independent of each other and (2) these three domains are related to other measures of self-control.
Strong Crack Blunting by Hierarchical Nanotwins in Ultrafine/Nano-grained Metals
Creators: name: Li, Jianjun
name: Ni, Yong
name: K. Soh, A.
name: Wu, X. L.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Infectious Diseases
subject: FOS: Health sciences
subject: Science Policy
subject: Cancer
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physics
subject: Biochemistry
subject: Biophysics

description: A theoretical model is proposed to illustrate the effect of detwinning of the secondary twin lamellae on the emission of lattice dislocations from a semi-infinite crack tip in a hierarchically nanotwinned metal. The results obtained show that the potential of the crack tip to emit dislocations can be optimized and greatly enhanced by tuning the secondary twin spacing, which leads to strong crack blunting. Moreover, the hierarchical structure is able to produce significant toughening at very thin secondary twin lamellae, as observed in molecular dynamics simulations. As a result, the proposed model suggests a novel toughening mechanism in ultrafine/nano-grained metals.
Supplementary data for Side-chain cleavage enzyme deficiency: our experience and gonadal function-focused systematic review
Creators: name: Phadte, Aditya
name: Lila, Anurag
Publisher: name: figshare
Year: 2022
Subjects: subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences
subject: 60107 Enzymes
subject: FOS: Biological sciences

description: Side-chain cleavage enzyme deficiency: our experience and gonadal function-focused systematic review
The Expression of Platelet-Activating Factor is Induced by Low Extracellular Mg2+ in Aortic, Cerebral and Neonatal Coronary Vascular Smooth Muscle; Cross Talk with Ceramide Production, NF–kB and Proto-Oncogenes: Possible Links to Atherogenesis and Sudden Cardiac Death in Children and Infants, and Aging; Hypothesis, Review and Viewpoint
Creators: name: SciDoc Publishers International Journal Of Cardiology And Research (IJCRR)
name: Altura BM
name: W, Li
name: A, Zhang
name: T, Zheng
name: Shah NC
name: Gatha J. Shah
name: Pérez-Albela JL
name: Altura BT
Publisher: name: figshare
Year: 2017
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: An attempt is made, herein, to reconcile, and integrate, various phenomena associated with magnesium deficiency (MgD) in cardiovascular health, disease, and aging as well as reasons for the high incidence of sudden cardiac death in infants and young adults. With new experiments, we demonstrate, for the first time, that very low concentrations of platelet-activating factor (PAF), when added to primary cultured cerebral, neonatal coronary, and aortic vascular smooth muscle (VSM) cells (from three different mammals) promote rapid rises in free intracellular Ca2+ ions and a significant, concomitant reduction in free intracellular Mg2+ ions; these actions of PAF being curtailed with a specific membrane-receptor inhibitor of PAF. Our new experiments also demonstrate that addition of PAF to the VSM cells result in activation of NF-kB, activation of the proto-oncogenes c-fos and c-jun, a generation/release of ceramide, and synthesis of DNA; most of these actions being inhibited by a specific membrane-receptor antagonist of PAF. In addition, we show, for the first time, formation of 4-hydroxy-2-nonenal (4-HNE) in VSM cells incubated in Mg-deficient (MgD) environments or after addition of PAF. This is important because 4-HNE is a well-known inducer of hydrogen peroxide, known to be formed in MgD VSM cells and that 4-HNE is known to induce DNA damage and fragmentation, events that we have shown previously in VSM and cardiac muscle cells exposed to low Mg environments. Lastly, our experiments demonstrate that incubation of cerebral, neonatal coronary and aortic VSM cells in low Mg2+ induces: 1. rapid formation of PAF which can be attenuated greatly with a specific membrane-receptor antagonist of PAF; and 2. rises in cellular levels of ceramide, NF-kB activation and formation of the proto-oncogenes, and synthesis of DNA, all of which could be inhibited with a specific membrane-receptor antagonist of PAF. These new findings suggest major roles for PAF (and probably PAF-like lipids) and ceramide formation in the cardiovascular manifestations of MgD, inflammation, atherogenesis, aging, and sudden cardiac death in children. The significance of our new findings are reviewed in light of other works on MgD, inflammation, atherogenesis, sudden cardiac death, and aging
MEASURING J-CURVE EFFECT USING EXCHANGE RATE INSTABILITY AND TRADE IMBALANCES: A QUANTITATIVE 3SLS APPROACH
Creators: name: Afzal, Fahim
name: Haiying, Pan
name: Afzal, Farman
name: Shah, Imran Ahmed
Publisher: name: figshare
Year: 2020
Subjects: subject: 150503 Marketing Management (incl. Strategy and Customer Relations)
subject: FOS: Economics and business

description: The exchange rate (ER) instability is an important factor in determining the trade-balance (Tb) of a country. Fluctuations in ER do affect the confidence level of shareholders, traders, and investors (stockbrokers and individual buyers) in the economy; if their confidence is shattered, then it will ultimately slow the trade process. The effect of ER instability on the Tb has been analyzed in this study that implies the impact of J-curve in Pakistan during the time of the 9/11 issue. This study is entirely quantitative considering the basic time-series of data consisting of the following variables; ER volatility, growth instability, export instability, agriculture and manufacturing instability, and trade instability. The instability values of imports, exports, ER, Tb, agriculture, and manufacturing variables have been calculated by using the variance obtained from generalized autoregressive conditional heteroscedasticity (GARCH). It has been found that for a short period, the impact of ER instability on exports is significantly positive with the coefficient of 0.2, but the negative impact of ER instability on imports is -0.2, respectively. Moreover, the relationship between the ER and terms of trade is significant, with a slightly negative coefficient of -0.13. Importantly, this study concludes that the J-curve effect does not work effectively due to different geostrategic problems in a region.
Abordagem da Hepatite Hipóxica no Cenário de Emergência: Protocolo de Revisão de Escopo
Creators: name: Do Nascimento, Maria Eduarda de Freitas Mesquita
name: Dias Vasconcelos, Lucas
name: Haddad, Julia Oliveira Dabien
name: Cirilo de Lucena Neto, Olival
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine

description: This document outlines the protocol for a scoping review researching the approach of Hypoxic Hepatitis (HH) in the emergency scenario.
“Nutritional or Hormonal”, The Myth of Takotsubo Cardiomyopathy and Left Ventricular Thrombosis in Anorexia Nervosa Patients! A Case Report
Creators: name: SciDoc Publishers International Journal Of Cardiology And Research (IJCRR)
name: H, Abdalla
name: Freyre A
name: Pynadath A
Publisher: name: figshare
Year: 2017
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Takotsubo Cardiomyopathy is a condition characterized by transient LV hypokinesis without evidence of obstructive coronary disease that is typically triggered by a stressful event. We describe a 34-year-old woman with anorexia nervosa presenting with hypotension, hypoglycemia, and tachycardia and found to have Takotsubo Cardiomyopathy. On admission, EKG showed ST depression with T wave inversion in the inferolateral leads and Q waves in the anteroseptal leads (V1-V3). The initial troponin was elevated at 1.2 ng/ml and increased to 1.94 ng/ml 4 hours later. Initial TTE showed global hypokinesisexcept for a hyperkinetic basal segment suggestive of takostsubo cardiomyopathy and an EF of 15-20%. During the course of management, subsequent TTEs revealed improved EF with resolution of the cardiomyopathy, but also the presence of an LV thrombus. The pathophysiology of Takotsubo Cardiomyopathy is not fully understood, and the impact of the hypoestrogenic state and the nutritional deficiencies on the development Takotsubo Cardiomyopathy in anorexia nervosa patients remains to be a myth.