cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Prices and Marketing Margins for Washington Delicious Apples Sold in Chicago and New York City, 1956-61
Creators: name: Edman, Victor G.
name: Edman, Victor G.
Publisher: name: Unknown
Year: 1963
Subjects: subject: Consumer/Household Economics
subject: Demand and Price Analysis
subject: Marketing
subject: FOS: Economics and business

description: Excerpt from the report Summary: The purposes of this study are: (1) to show the extent and nature of Washington Delicious apple price variations, and (2) to indicate the size of the total marketing margin for Washington Delicious apples and its allocation to the various marketing agencies. Retail prices, auction prices, and marketing margins are presented for Washington Delicious apples sold through auction in Chicago and New York City. Retail prices averaged higher in Chicago than New York City 4 of the 5 seasons studied, but auction prices were higher in New York City during 4 of the 5 seasons. Retail and auction price movements in the 2 markets were in the same direction but usually not in the same amounts. Seasonal prices were closely related (inversely) to the annual production of apples, particularly Washington Delicious. As a consequence of wide variations in production between seasons, prices between seasons varied considerably. Prices over a season, however, tended to be relatively stable at a level determined by the volume of production and other factors.
Novel Agents in the Treatment of Unresectable Neuroendocrine Tumors
Creators: name: Oberstein, Paul E
name: Saif, Muhammad Wasif
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Drug Therapy; everolimus; Neuroendocrine Tumors; Pancreatic Neoplasms

description: Pancreatic neuroendocrine tumors represent a small percentage of all pancreatic tumors (1.3%) but their incidence is rising. Prior to 2011, the only approved agent for unresectable disease was streptozicin (often used in combination with doxorubicin) but the efficacy of this drug is in question and there had not been any new drugs approved for this disease in more than 20 years. Recently there has been new excitement for the treatment of advanced neuroendocrine tumors including those of the pancreas (pNET) with FDA approval of 2 new agents in 2011. One of these agents was everolimus, an mTOR inhibitor, which was approved on the basis of a landmark phase III study (RADIANT-3). At the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting, several abstracts were presented reviewing novel agents in the treatment of advanced NET. Three abstracts looked at characteristics of patients treated on the RADIANT-3 study and looked at the role of prior chemotherapy use (Abstract #4103), somatostatin analog use (Abstract #4010), and updated safety data (Abstract #4009) from this trial. Additionally, an abstract was presented (Abstract 4008) looking at updated data from the other targeted agent approved for advanced pNET, sunitinib, a multi-tyrosine kinase inhibitor, which demonstrated improvement in progression-free survival compared to placebo. Novel agents were also presented, including a phase II trial looking at the combination of sorafenib and bevacizumab (Abstract #4113), and a phase I trial looking at a novel somatostatin analog, pasireotide, in combination with everolimus (Abstract #4120) The authors review and summarize these abstracts in this article.

Image: Mosaic on the wall of the 116th Street station on the 1st line of the New York subway system.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Modelling the inner disc of the Milky Way with manifolds. I - A first step
Creators: name: Romero-Gomez, M.
name: Athanassoula, E.
name: Antoja, T.
name: Figueras, F.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We study the bar-driven dynamics in the inner part of the Milky Way by using invariant manifolds. This theory has been successfully applied to describe the morphology and kinematics of rings and spirals in external galaxies, and now, for the first time, we apply it to the Milky Way. We compute the orbits confined by the invariant manifolds of the unstable periodic orbits located at the ends of the bar. We discuss whether the COBE/DIRBE bar and the Long bar compose a single bar or two independent bars and perform a number of comparisons which, taken together, argue strongly in favour of the former. More specifically, we favour the possibility that the so-called COBE/DIRBE bar is the boxy/peanut bulge of a bar whose outer thin parts are the so-called Long bar. This possibility is in good agreement both with observations of external galaxies, with orbital structure theory and with simulations. We then analyse in detail the morphology and kinematics given by five representative Galactic potentials. Two have a Ferrers bar, two have a quadrupole bar and the last one a composite bar. We first consider only the COBE/DIRBE bar and then extend it to include the effect of the Long bar. We find that the large-scale structure given by the manifolds describes an inner ring, whose size is similar to the near and far 3-kpc arm, and an outer ring, whose properties resemble those of the Galactic Molecular Ring. We also analyse the kinematics of these two structures, under the different galactic potentials, and find they reproduce the main over-densities found in the galactic longitude-velocity CO diagram. Finally, we consider for what model parameters, the global morphology of the manifolds may reproduce the two outer spiral arms. We conclude that this would necessitate either more massive and more rapidly rotating bars, or including in the potential an extra component describing the spiral arms.
description: 18 pages, 11 figures, accepted in MNRAS
eleMHR
Creators: name: Gan, Jing
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 310201
subject: Bioinformatic methods development
classificationCode: 310207
subject: Statistical and quantitative genetics

description: eleMHR is a computational method for discovering mutation hotspot regions in genomic elements (CDS, 3UTR, 5UTR, promoters, splice site, etc.) to identify cancer driver genes genome-wide.eleMHR quantifies the enrichment of somatic mutations and detects mutation hotspot regions in genomic elements based on mutation set enrichment analysis. Two major files are required by eleMHR: a set of genomic regions of interest element, and a set of somatic mutations in a tumor cohort, they are all in tab-separated text files. The element files we provide have two reference genomes containing hg19 and hg38. Users can make their selection based on the reference genome of somatic mutations. The match between somatic mutations and element region is completed by R code match_mutations_elements.R and generates element_mutations files. The eleMHR code has both R and Java versions for users.
Adjuvant Treatment for Ampullary Cancer
Creators: name: Kim, Richard
name: Chabot, John
name: Saif, Muhammad Wasif
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Ampulla of Vater; Drug Therapy; gemcitabine; Pancreatic Neoplasms

description: Ampullary cancer is an uncommon tumor and tends to have a better prognosis than pancreatic cancer. However, one half of patients will die from recurrent disease suggesting the need for effective adjuvant therapy. Currently, there is lack of randomized trials to guide the use of adjuvant therapy in ampullary cancer. At the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting, the largest trial (Abstract #4006) evaluating adjuvant treatment of ampullary cancer was presented.

Image: H. Lee Moffitt Cancer Center. Tampa, FL, USA.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Quantifying the role of bars in the build-up of central mass concentrations in disk galaxies
Creators: name: Wang, Jing
name: Kauffmann, Guinevere
name: Overzier, Roderik
name: Tacconi, Linda J.
name: Kong, Xu
name: Saintonge, Amelie
name: Catinella, Barbara
name: Schiminovich, David
name: Moran, Sean M.
name: Johnson, Benjamin
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We analyze the role of bars in the build-up of central mass concentrations in massive, disk galaxies. Our parent sample consists of 3757 face-on disk galaxies with redshifts between 0.01 and 0.05, selected from the seventh Data Release of the Sloan Digital Sky Survey. 1555 galaxies with bars are identified using position angle and ellipticity profiles of the $i$-band light. We compare the ratio of the specific star formation rate measured in the 1-3 kpc central region of the galaxy to that measured for the whole galaxy. Galaxies with strong bars have centrally enhanced star formation; the degree of enhancement depends primarily on the ellipticity of the bar, and not on the size of the bar or on the mass or structure of the host galaxy. The fraction of galaxies with strong bars is highest at stellar masses greater than $3 \times 10^{10} M_{\odot}$, stellar surface densities less than $3 \times 10^8 M_{\odot}$ and concentration indices less than 2.5. In this region of parameter space, galaxies with strong bars either have enhanced central star formation rates, or star formation that is {\em suppressed} compared to the mean. This suggests that bars may play a role in the eventual quenching of star formation in galaxies. Only 50% of galaxies with strongly concentrated star formation have strong bars, indicating that other processes such as galaxy interactions also induce central star-bursts. We also find that the ratio of the size of the bar to that of the disk depends mainly on the colour of the galaxy, suggesting that the growth and destruction of bars are regulated by gas accretion, as suggested by simulations.
description: 17 pages, 14 figures. Accepted for publication in MNRAS
Mitteilungen
Creators: name: Redaktion, Die
Publisher: name: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege
Year: 2019

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 48 Nr. 4 (2019)
From étale $P_{+}$-representations to $G$-equivariant sheaves on $G/P$
Creators: name: Schneider, Peter
name: Vigneras, Marie-France
name: Zabradi, Gergely
Publisher: name: arXiv
Year: 2012
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11F70, 20G25

description: Let $K/\mathbb Q_{p}$ be a finite extension with ring of integers $o$, let $G$ be a connected reductive split $\mathbb Q_{p}$-group of Borel subgroup $P=TN$ and let $α$ be a simple root of $T$ in $N$. We associate to a finitely generated module $D$ over the Fontaine ring over $o $ endowed with a semilinear étale action of the monoid $T_{+} $ (acting on the Fontaine ring via $α$), a $G(\mathbb Q_{p})$-equivariant sheaf of $o$-modules on the compact space $G(\mathbb Q_{p})/P(\mathbb Q_{p})$. Our construction generalizes the representation $D\boxtimes \mathbb P^{1} $ of $ GL(2,\mathbb Q_{p})$ associated by Colmez to a $(φ,Γ)$-module $D$ endowed with a character of $\mathbb Q_{p}^{*}$.
Giffen, A. G. van: De Hunebedden in Nederland
Creators: name: Jacob-Friesen, Karl Hermann
Publisher: name: Nachrichten aus Niedersachsens Urgeschichte
Year: 2020

description: Rezension zu: Giffen, A. G. van: De Hunebedden in Nederland. 4°. Bd. 1. 244 S. Bd. 2. 580 S. mit 22 Textabb. Atlas Teil 1 mit 120 Taf. Teil 2 mit 34 Taf. z.T. in Lichtdruck. Utrecht 1925-1927
description: Nachrichten aus Niedersachsens Urgeschichte, Bd. 1 (1927): Nachrichten aus Niedersachsens Urgeschichte
Gravity Dual for Hofman-Strominger Theorem
Creators: name: Nakayama, Yu
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We provide a gravity counterpart of the theorem by Hofman and Strominger that in (1+1) dimension, chiral scale invariance indicates chiral conformal invariance. We show that the strict null energy condition gives a sufficient condition to guarantee the symmetry enhancement. We also investigate a possibility to construct holographic c-function that decreases along the holographic renormalization group flow.
description: 6 pages
Manchester Library Digital Scholarship showcase
Creators: name: Reed, Phil
name: Beard, Lorraine
Publisher: name: University of Manchester
Year: 2023
Subjects: Other education not elsewhere classified

description: We saw ‘Manchester Library Digital Scholarship’ appear in the second annual report of Imagine2030 as a major new piece of work. In this session, we seek your input on how the Library can offer support for digital scholarship using its amazing collections, expertise and ethical values. Try some digital scholarship tools and experience Manchester Digital Collections, Manchester Digital Exhibitions, advanced imaging and a selection of our innovative subscribed content. Contribute to our panel discussion about the intersection between digital scholarship, inclusivity, sustainability, artificial intelligence and ethics. Be inspired to think about how digital scholarship affects your area of work and contribute to a vision for a uniquely Manchester Library digital scholarship.
Emergence: Key physical issues for deeper philosophical inquiries
Creators: name: Hu, Bei-Lok
Publisher: name: arXiv
Year: 2012
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A sketch of three senses of emergence and a suggestive view on the emergence of time and the direction of time is presented. After trying to identify which issues philosophers interested in emergent phenomena in physics view as important I make several observations pertaining to the concepts, methodology and mechanisms required to understand emergence and describe a platform for its investigation. I then identify some key physical issues which I feel need be better appreciated by the philosophers in this pursuit. I end with some comments on one of these issues, that of coarse-graining and persistent structures.
description: 16 pages. Invited Talk at the Heinz von Foerster Centenary International Conference on Self-Organization and Emergence: Emergent Quantum Mechanics (EmerQuM11). Nov. 10-13, 2011, Vienna, Austria. Proceedings to appear in J. Phys. (Conf. Series)
Evaluation of the Quality of Life after Surgical Treatment of Chronic Pancreatitis
Creators: name: Hildebrand, Philipp
name: Duderstadt, Stefanie
name: Jungbluth, Thomas
name: Roblick, Uwe Johannes
name: Bruch, Hans-Peter
name: Czymek, Ralf
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Pancreatitis, Chronic; Quality of Life; Surgical Procedures, Operative

description: Objective Pain is the main symptom of chronic pancreatitis. However, in addition to an improvement in pain symptoms, an increase in the quality of life also influences therapeutic success. The present paper evaluates the influence of surgery on chronic pancreatitis, and the early and late postoperative quality of life. Patients From March 2000 until April 2005, 51 patients underwent surgical treatment for chronic pancreatitis at our institution. Intervention Thirty-nine (76.5%) patients were operated on according to the Frey procedure and, in 12 (23.5%) patients, a Whipple procedure was performed. Study design Patient data were documented throughout the duration of the hospital stay. Postoperative follow-up data were recorded retrospectively. Main outcome measures Postoperative follow-up with postoperative pain scores and quality of life were carried out using a standardized questionnaire. Results During a median follow-up period of 50 months, an improvement in pain scores was observed in 92.3% of the patients in the Frey group and in 66.7% in the Whipple group. The indices for global quality of life and for physical and emotional status increased in both surgical groups. Conclusion For patients with chronic pancreatitis, the decisive factor is the quality of life, particularly concerning pain and metabolic changes. The Frey procedure seems to offer advantages with respect to long-term freedom of pain and low risk of surgery-induced pancreatic insufficiency.

Image: University of Schleswig-Holstein. Lübeck, Germany.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Spectral calibration and modeling of the NuSTAR CdZnTe pixel detectors
Creators: name: Kitaguchi, Takao
name: Grefenstette, Brian W.
name: Harrison, Fiona A.
name: Miyasaka, Hiromasa
name: Bhalerao, Varun B.
name: Cook, Walter R.
name: Mao, Peter H.
name: Rana, Vikram R.
name: Boggs, Steven E.
name: Zoglauer, Andreas C.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The Nuclear Spectroscopic Telescope Array (NuSTAR) will be the first space mission to focus in the hard X-ray (5-80 keV) band. The NuSTAR instrument carries two co-aligned grazing incidence hard X-ray telescopes. Each NuSTAR focal plane consists of four 2 mm CdZnTe hybrid pixel detectors, each with an active collecting area of 2 cm x 2 cm. Each hybrid consists of a 32 x 32 array of 605 micron pixels, read out with the Caltech custom low-noise NuCIT ASIC. In order to characterize the spectral response of each pixel to the degree required to meet the science calibration requirements, we have developed a model based on Geant4 together with the Shockley-Ramo theorem customized to the NuSTAR hybrid design. This model combines a Monte Carlo of the X-ray interactions with subsequent charge transport within the detector. The combination of this model and calibration data taken using radioactive sources of Co-57, Eu-155 and Am-241 enables us to determine electron and hole mobility-lifetime products for each pixel, and to compare actual to ideal performance expected for defect-free material.
description: 11 pages, 10 figures, to appear in Proceedings of the SPIE Conference 8145: UV, X-Ray, and Gamma-Ray Space Instrumentation for Astronomy XVII
Made-to-measure galaxy models - II Elliptical and Lenticular Galaxies
Creators: name: Long, R. J.
name: Mao, Shude
Publisher: name: arXiv
Year: 2012
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We take a sample of 24 elliptical and lenticular galaxies previously analysed by the SAURON project using three-integral dynamical models created with Schwarzschild's method, and re-analyse them using the made-to-measure (M2M) method of dynamical modelling. We obtain good agreement between the two methods in determining the dynamical mass-to-light (M/L) ratios for the galaxies with over 80% of ratios differing by < 10% and over 95% differing by < 20%. We show that (M/L)_M2M is approximately equal to (M/L)_Sch. For the global velocity dispersion anisotropy parameter delta, we find similar values but with fewer of the made-to-measure models tangentially anisotropic by comparison with their SAURON Schwarzschild counterparts. Our investigation is the largest comparative application of the made-to-measure method to date.
description: 14 pages, 8 figures and 5 tables
Ein steinzeitliches Hügelgrab in der Feldmark Bargstedt, Kr. Stade
Creators: name: Wegewitz, Willi
Publisher: name: Nachrichten aus Niedersachsens Urgeschichte
Year: 2020

description: Nachrichten aus Niedersachsens Urgeschichte, Bd. 2 (1928): Nachrichten aus Niedersachsens Urgeschichte
Using the 4-hour Post-ERCP Amylase Level to Predict Post-ERCP Pancreatitis
Creators: name: Sutton, Verity R
name: Hong, Michael K Y
name: Thomas, Peter R
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Amylases; Cholangiopancreatography, Endoscopic Retrograde /complications; Pancreatitis

description: Context Post-ERCP pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). A simple method of predicting patients who are at risk of developing post-ERCP pancreatitis is needed to allow those at low risk to be discharged on the same day of their procedure. The aim of this study was to confirm that 4-hour post-ERCP serum amylase level is predictive of post-ERCP pancreatitis. Patients A study of 886 ERCPs performed at a single centre was conducted. Main outcome measure Four-hour amylase level was recorded, along with patient demographics, procedural details, presence of pancreatogram, and morbidity and mortality. Results Pancreatitis occurred in 4.4% of ERCPs. Hyperamylasaemia was found to be predictive of post-ERCP pancreatitis, with other risk factors being a younger age and pancreatogram. Hyperamylasaemia was also predictive of post-ERCP pancreatitis in the subgroup of patients who had undergone pancreatogram. Conclusions The 4-hour amylase level is a useful measure in the prediction of post-ERCP pancreatitis. Patients who have undergone pancreatogram should be admitted if 4-hour amylase level is greater than 2.5 times the upper limit of reference. Patients who have not undergone pancreatogram should be admitted if 4-hour amylase level is greater than 5 times the upper limit of reference.

Image: Proposed algorithm for selecting patients for same-day discharge post-ERCP.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Inoperable Pancreatic Cancer Patients Who Have Prolonged Survival Exhibit an Increased Risk of Cholangitis
Creators: name: Buxbaum, James L
name: Biggins, Scott W
name: Bagatelos, Karen C
name: Inadomi, John M
name: Ostroff, James W
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Cholangitis; Cholestasis, Extrahepatic; Pancreatic Neoplasms; Stents

description: Context Endoscopically placed metal stents, which are patent for 4-9 months, have been the favored decompressive strategy for biliary obstruction due to inoperable pancreatic cancer in order to minimize interventions. However, in the past decade chemotherapeutic options have improved survival. This raises the question of whether metal stents will continue to be the optimal method of decompression. Objective We performed a study to determine the outcome of patients with non-operatively managed pancreatic adenocarcinoma with regards to the development of cholangitis. Design We reviewed all ERCP performed for malignant distal biliary obstruction in between December 1999 and December 2005 at University of California, San Francisco (UCSF). Patients Only patients who received chemotherapy for pancreatic adenocarcinoma were included. Patients who underwent surgical biliary diversion procedures were excluded. Primary outcome measurement The primary outcome was the development of cholangitis requiring hospitalization. Results Among 200 patients with malignant distal biliary obstruction who underwent endoscopic biliary decompression procedures, 54 met study criterion. Metal stents were employed in 90.7% of these cases. The median survival of this population was 12.7 months (range: 2.6-34.6 months). Only 3 of 26 patients (11.5%) surviving one year or less developed cholangitis compared to 13 of 28 (46.5%) who survived more than one year. Thus patients surviving greater than one year had a five fold increase in the odds of developing cholangitis (odds ratio: 4.92; P=0.017). Conclusions This cohort of inoperable pancreatic cancer patients undergoing chemotherapy survived longer than the expected patent period of metal stents employed for biliary decompression. The occurrence of cholangitis requiring hospitalization does increase markedly among long term survivors.

Image: Number of patients who survived.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Theoretical Study of Hydrogenated Tetrahedral Aluminum Clusters
Creators: name: Ichikawa, Kazuhide
name: Ikeda, Yuji
name: Wagatsuma, Ayumu
name: Watanabe, Kouhei
name: Szarek, Pawel
name: Tachibana, Akitomo
Publisher: name: arXiv
Year: 2011
Subjects: subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We report on the structures of aluminum hydrides derived from a tetrahedral aluminum Al4 cluster using ab initio quantum chemical calculation. Our calculation of binding energies of the aluminum hydrides reveals that stability of these hydrides increases as more hydrogen atoms are adsorbed, while stability of Al-H bonds decreases. We also analyze and discuss the chemical bonds of those clusters by using recently developed method based on the electronic stress tensor.
description: 15 pages, 7 figures, published online, International Journal of Quantum Chemistry
CT Attenuation of Unilocular Pancreatic Cystic Lesions to Differentiate Pseudocysts from Mucin-Containing Cysts
Creators: name: Chalian, Hamid
name: Töre, Hüseyin Gürkan
name: Miller, Frank H
name: Yaghmai, Vahid
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Cysts, Pancreas; Densitometry; Pancreatic Pseudocyst

description: Context There is extensive overlap among the imaging characteristics of pseudocyst, mucinous cystic neoplasm (MCN) and side branch intraductal papillary mucinous neoplasm (IPMN) on CT images. Objective The purpose of this study was to evaluate the usefulness of attenuation measurement in differentiating pseudocysts from MCN and IPMN of pancreas on CT images. Patients Seventy-five pathologically proven unilocular pancreatic cysts including 31 pseudocysts, 29 MCN and 15 IPMN imaged with multidetector computed tomography (MDCT) before resection were evaluated. Main outcome measures Attenuation values were measured by conventional region of interest (ROI) method. Design Attenuation values (in Hounsfield unit, HU) were compared between the cyst pathologies. Receiver operating characteristic (ROC) curve analysis was performed to obtain the best attenuation threshold between mucin-containing cysts and pseudocysts. Correlation between attenuation values and cyst size was assessed. Results Maximum transaxial diameters of pseudocysts (4.5 cm), MCNs (3.7 cm) and IPMNs (4.0 cm) were comparable (P=0.919). Mean attenuation was 18.9 HU, 13.0 HU and 11.4 HU for pseudocyst, MCNs and IPMNs, respectively. Attenuations were significantly higher in pseudocysts versus mucin-containing (MCN+IPMN) cysts (P=0.001) and comparable between MCNs and IPMNs (P=0.390). ROC curve showed 14.5 HU the best cut-off (accuracy: 73.5%) for differentiating pseudocysts from mucin-containing cysts (P<0.001). Pancreatic cyst attenuation measurement did not significantly correlate with cyst size (r=-0.03, P=0.772). Conclusion Attenuation measurement may help in differentiating pseudocysts from unilocular mucin-containing simple cysts of the pancreas on CT images.

Image: Mean and 95%CI of the attenuation in pseudocyst, MCN and IPMN.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Substance P and Calcitonin Gene Related Peptide Mediate Pain in Chronic Pancreatitis and Their Expression is Driven by Nerve Growth Factor
Creators: name: Liu, LianSheng
name: Shenoy, Mohan
name: Pasricha, Pankaj Jay
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Calcitonin Gene-Related Peptide; Nerve Growth Factor; Pancreatitis, Chronic; Rats; Substance P

description: Context Calcitonin gene-related peptide (CGRP), substance P and nerve growth factor play an important role in inflammatory pain in various somatic pain models but their role in chronic pancreatitis has not been well studied. Objectives The aim of this study was to investigate the effects of intrathecal administration of calcitonin gene-related peptide antagonist and substance P receptor antagonist on pain behavior in a rat model of chronic pancreatitis and to determine whether nerve growth factor drives the up-regulation of expression of these neuropeptides in sensory neurons. Methods Pancreatitis was induced by retrograde infusion of trinitobenzene sulfonic acid into the pancreatic duct of adult rats. Three weeks post infusion continuous intrathecal infusion of the calcitonin gene-related peptide antagonist alpha CGRP8-37 or neurokinin-1 receptor antagonist CP-96345 or its inactive enantiomer CP-96344 was administered for seven days. The effects of treatment on pancreatic hyperalgesia were assessed by sensitivity of the abdominal wall to von Frey filament probing as well as by the nocifensive response to electrical stimulation of the pancreas. In a separate experiment chronic pancreatitis was induced and pancreas specific dorsal root ganglion neurons labeled with DiI were assessed for calcitonin gene-related peptide and substance P immunoreactivity. Results Intrathecal infusion of calcitonin gene-related peptide and neurokinin-1 receptor antagonists significantly attenuated behavioral pain responses in rats with chronic pancreatitis. Further, treatment of chronic pancreatitis rats with nerve growth factor antibody significantly reduced pancreas specific neurons expressing calcitonin gene-related peptide and substance P in thoracic dorsal root ganglion. Conclusions Calcitonin gene-related peptide and substance P mediate pancreatic hyperalgesia in chronic pancreatitis and nerve growth factor in turn sustains the up-regulation of these neuropeptides in pancreatic sensory neurons.

Image: Anti-NGF treatment results in downregulation of substance P and CGRP.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
The Pattern of Neural Elements in the Islets of Normal and Diseased Pancreas and in Isolated Islets
Creators: name: Pour, Parviz M
name: Saruc, Murat
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: beta III-tubulin protein, human; Insulin-Secreting Cells; Islets of Langerhans; Pancreatic Neoplasms; Pancreatitis, Chronic; Tissue Donors

description: Context The association between islet cells and neural elements, the so-called “neuro-insular complex”, has been known for centuries. Objective We examined the expression of beta-III tubulin, in normal pancreases from organ donors, surgical specimens of chronic pancreatitis, surgical specimens of ductal type carcinoma, isolated and purified islets of a 57-year-old male and the pancreases of adult Syrian golden hamsters by immunohistochemistry using a monoclonal antibody to beta-tubulin. Results In the normal pancreas of humans and hamsters, beta-III tubulin was expressed in alpha- and beta-cells, but not in PP cells, neural fibers and gangliae. Occasionally, intra-and peri-insular neural elements were also found. In chronic pancreatitis and pancreatic cancer samples, the number of beta-cells and the immunoreactivity of the beta-III tubulin antibody in islet cells were decreased in most cases. In cultured human islets, devoid of neural elements, no correlation was found between the expression of beta-III tubulin and islet cell hormones. Conclusion Beta-III tubulin is only expressed in the islets derived from the dorsal pancreas and in neural elements. In chronic pancreatitis and pancreatic cancer swelling of intra- and peri-insular nerves occurs, possibly in response to the loss of beta-cells. The secretion of insulin and the expression of beta-tubulin seem to be regulated by nerves.
Image: Multi-labeling of normal pancreatic islets.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Sedimentation as a Measure of Wheat Quality, 1962 Crop
Creators: name: Zeleny, Lawrence
name: Doty, James M.
name: Kibler, William E.
name: Zeleny, Lawrence
name: Doty, James M.
name: Kibler, William E.
Publisher: name: Unknown
Year: 1963
Subjects: subject: Crop Production/Industries
subject: Marketing
subject: FOS: Economics and business
subject: Research and Development/Tech Change/Emerging Technologies
subject: Research Methods/ Statistical Methods

description: Report Summary: In a broad survey of the quality of the U. S. 1962 hard red winter and hard red spring wheat crops covering 31 areas of production, wheat sedimentation was found to be superior to protein content and to each of the important farinogram characteristics as a means of predicting bread-baking quality. Wheat sedimentation value was also found to be superior to wheat protein content as a means of predicting mixing time, mixing tolerance, M.T.I. value, and valorimeter value as determined by the farinograph. The superiority of sedimentation over protein and over all farinogram characteristics as a measure of bread-baking quality was found to be quite great in most areas both for hard red winter wheat and hard red spring wheat, but especially so in the case of hard red spring wheat.
Dirce chrześcijańska Henryka Siemiradzkiego i Pojedynek Ilji Riepina na Drugim Biennale w Wenecji w 1897 roku
Creators: name: Chasjanowa, Lejła
Publisher: name: Pamiętnik Sztuk Pięknych / Fine Arts Diary
Year: 2019

description: Pamiętnik Sztuk Pięknych / Fine Arts Diary, Bd. 10 (2015): Pamiętnik Sztuk Pięknych / Fine Arts Diary
Acute Pancreatitis in the Course of Meprobamate Poisoning
Creators: name: Fathallah, Neila
name: Zamy, Michele
name: Slim, Raoudha
name: Fain, Olivier
name: Hmouda, Houssem
name: Bouraoui, Kamel
name: Salem, Chaker Ben
name: Biour, Michel
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Meprobamate, poisoning, pancreatitis

description: Context We report a case of massive poisoning with meprobamate leading to acute pancreatitis. Case report A 43-year-old patient with a history of schizophrenia and multiple suicide attempts was admitted to the intensive care unit for severe poisoning with meprobamate (voluntary ingestion of 60 g). On admission, the patient was deeply comatose with low blood pressure and hypothermia. Laboratory analysis revealed leukocytosis and high lipase and amylase serum levels. There was no eosinophilia. Abdominal computed tomography showed pancreatitis grade A. The patient was intubated and ventilated, and intravenous dopamine was infused. The patient regained consciousness and was extubated five days later. Improvement in pancreatic tests was noted several days later. The outcome was favorable. Discussion According to the Naranjo probability scale, meprobamate-induced acute pancreatitis was probable. Acute pancreatitis in meprobamate poisoning is exceptional. The pathogenesis of pancreatitis-induced meprobamate poisoning may be explained by two mechanisms: stimulation of pancreatic secretion secondary to cholinergic activation and pancreatic ductal hypertension. Conclusions The signs of severe meprobamate toxicity are numerous including cardiovascular and central nervous symptoms. Acute pancreatitis should also be added as a possible manifestation of meprobamate poisoning.

Image: Faculty of Medicine of Sousse. Sousse, Tunisia.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Arbuscular mycorrhizal fungi (AMF) root colonization dynamics of Molinia caerulea (L.) Moench. in grasslands and post-industrial sites
Creators: name: Sierka, Edyta
Publisher: name: figshare
Year: 2021
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Bąba, W., Błońska, A., Kompała-Bąba, A., Małkowski, Ł., Ziemer, B., Sierka, E., Nowak, T., Woźniak, G., Besenyei, L. 2016. Arbuscular mycorrhizal fungi (AMF) root colonization dynamics of Molinia caerulea (L.) Moench. in grasslands and post-industrial sites. Ecological Engineering Vol. 95, 817-827.
Autoimmune Neutropenia Associated with Autoimmune Pancreatitis
Creators: name: Sato, Shuzo
name: Irisawa, Atushi
name: Sato, Ai
name: Shibukawa, Goro
name: Suzuki, Rei
name: Takagi, Tadayuki
name: Ikeda, Tsunehiko
name: Sato, Masaki
name: Hikichi, Takuto
name: Obara, Katsutoshi
name: Ohira, Hiromasa
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Autoimmune Diseases; Immunoglobulin G; Neutropenia; Pancreatitis

description: Context We report a rare case of autoimmune neutropenia associated with autoimmune pancreatitis. Case report A 61-year-old man was referred to our hospital with slight epigastralgia. He had been admitted to another hospital with exacerbation of diabetes and jaundice. Blood tests showed low white blood cell and neutrophil counts (1,800 µL-1 and 3%, respectively), and elevated transaminase, biliary enzyme, amylase and lipase levels. Serum IgG and IgG4 levels were elevated to 2,693 mg/dL and 454 mg/dL, respectively. Abdominal CT showed diffuse pancreatic swelling, and MRCP revealed diffuse narrowing of the main pancreatic duct and dilation of the common bile duct. An additional EUS-FNA was performed in our hospital. Laboratory data, imaging and histopathological findings confirmed the diagnosis of autoimmune pancreatitis. However, the low white blood cell count continued. For additional investigation, a bone marrow examination was performed, indicating a granulocyte maturation disorder. Moreover, anti-neutrophil antibodies were positive. Therefore, a diagnosis of autoimmune neutropenia associated with autoimmune pancreatitis was made. After steroid therapy, the anti-neutrophil antibodies disappeared and the white blood cell count was within the reference limit. No recurrence of disease has been observed since then. Conclusion Autoimmune neutropenia, which is positive for anti-neutrophil antibodies, can be associated with autoimmune pancreatitis.

Image: Clinical course.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Delayed Pancreatic Fistula After Pancreaticoduodenectomy. A Case Report
Creators: name: Ito, Yasuhiro
name: Irino, Tomoyuki
name: Egawa, Tomohisa
name: Hayashi, Shinobu
name: Nagashima, Atsushi
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Pancreatic Fistula; Postoperative Complications; Pancreaticoduodenectomy

description: Context Pancreatic fistulas still occur despite refinements in both surgical technique and perioperative management after a pancreaticoduodenectomy. However, the occurrence of delayed pancreatic fistulas is very rare. Case report A 62-year-old woman diagnosed with a lower biliary carcinoma had undergone a pylorus-preserving pancreaticoduodenectomy. The postoperative course was uneventful and the patient was discharged from the hospital after 16 days. One year after surgery, she was admitted to our hospital with a fluid collection around the pancreaticojejunal anastomosis. A catheter was inserted percutaneously and the fluid collection was drained. The amylase value of the discharge was significantly elevated (119,500 IU/L). One week later, a fistulography showed no significant collection and the tube was clamped. The patient was discharged from the hospital without symptoms. Conclusions It is important to consider the occurrence of a delayed pancreatic fistula if the patient suffers from any symptoms. It is then necessary to proceed rapidly.

Image: Fistulography showing the disappearance of the fluid collection around the pancreaticojejunal anastomosis.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
On Universal Tilers
Creators: name: Wang, David G. L.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05B45

description: A famous problem in discrete geometry is to find all monohedral plane tilers, which is still open to the best of our knowledge. This paper concerns with one of its variants that to determine all convex polyhedra whose every cross-section tiles the plane. We call such polyhedra universal tilers. We obtain that a convex polyhedron is a universal tiler only if it is a tetrahedron or a pentahedron.
description: 10 pages, 2 figures
Foregut Cystic Malformations in the Pancreas. Are Definitions Clearly Established?
Creators: name: Gómez Mateo, María Del Carmen
name: Muñoz Forner, Elena
name: Sabater Ortí, Luis
name: Ferrández Izquierdo, Antonio
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Bronchogenic Cyst; Congenital Abnormalities; Mediastinal Cyst; Pancreas; Pancreatic Cyst

description: Context Foregut cystic malformations are common lesions in the mediastinum but are rarely found in subdiaphragmatic locations. Only a few cases have been described within the pancreas where they can easily be misdiagnosed as cystic neoplasms. Case report We herein present the case of a 37-year-old female with acute cholangitis in whom a diagnostic work-up revealed a 1 cm solid-cystic heterogeneous lesion located at the head of the pancreas. The patient underwent a pancreaticoduodenectomy. Pathological evaluation demonstrated a cystic cavity lined by pseudostratified tall columnar ciliated epithelium with goblet cells, but lacking cartilage or smooth muscle bundles. Thus, the final diagnosis of the lesion was a ciliated foregut cyst of the pancreas. Conclusions A review of the cases published regarding these lesions shows great variability in the taxonomy and a lack of accuracy in the definitions of each different subtype. An easy to use algorithm for the diagnosis of foregut cystic malformations subtypes, based on epithelial lining and wall features, is presented.

Image: Diagnostic algorithm of the different foregut cystic malformations.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
The ''Hanging Maneuver'' Technique during Pancreaticoduodenectomy: The Result of a Technical Evolution to Approach the Superior Mesenteric Artery
Creators: name: Marzano, Ettore
name: Piardi, Tullio
name: Pessaux, Patrick
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Adenocarcinoma; Mesenteric Artery, Superior; Pancreatic Neoplasms; Pancreaticoduodenectomy

description: No abstract available.

Image: “Hôpital de Hautepierre”. Strasbourg, France.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Universality of the Plastic Instability in Strained Amorphous Solids
Creators: name: Dasgupta, Ratul
name: Karmakar, Smarajit
name: Procaccia, Itamar
Publisher: name: arXiv
Year: 2011
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: By comparing the response to external strains in metallic glasses and in Lenard-Jones glasses we find a quantitative universality of the fundamental plastic instabilities in the athermal, quasistatic limit. Microscopically these two types of glasses are as different as one can imagine, the latter being determined by binary interactions, whereas the former by multiple interactions due to the effect of the electron gas that cannot be disregarded. In spite of this enormous difference the plastic instability is the same saddle-node bifurcation. As a result the statistics of stress and energy drops in the elasto-plastic steady state are universal, sharing the same system-size exponents.
When Pathology Marries Clinics: the Honolulu Consensus Document and the Guidelines of the International Association of Pancreatology on Autoimmune Pancreatitis
Creators: name: Uomo, Generoso
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Autoimmune Diseases; Pancreatic Neoplasms; Pancreatitis, Chronic; Practice Guidelines as Topic

description: No abstract available.
description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
Particle transport in density gradient driven TE mode turbulence
Creators: name: Skyman, Andreas
name: Nordman, Hans
name: Strand, P. I.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The turbulent transport of main ion and trace impurities in a tokamak device in the presence of steep electron density gradients has been studied. The parameters are chosen for trapped electron (TE) mode turbulence, driven primarily by steep electron density gradients relevant to H-mode physics, but with a transition to temperature gradient driven turbulence as the density gradient flattens. Results obtained through non-linear (NL) and quasilinear (QL) gyrokinetic simulations using the GENE code are compared with results obtained from a fluid model. Main ion and impurity transport is studied by examining the balance of convective and diffusive transport, as quantified by the density gradient corresponding to zero particle flux (peaking factor). Scalings are obtained for the impurity peaking with the background electron density gradient and the impurity charge number. It is shown that the impurity peaking factor is weakly dependent on impurity charge and significantly smaller than the driving electron density gradient.
description: 11 pages, 6 figures. Submitted to Nuclear Fusion SPE
Hot articles recently published in the field of pancreatology
Creators: name: Fioravanti, Antonella
Publisher: name: JOP. Journal of the Pancreas
Year: 2011
Subjects: Collected Works; Pancreas; Pancreatic Diseases; Pancreatic Neoplasms

description: JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.  316-434
On the twin paradox in static spacetimes: I. Schwarzschild metric
Creators: name: Sokolowski, Leszek M.
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Motivated by a conjecture put forward by Abramowicz and Bajtlik we reconsider the twin paradox in static spacetimes. According to a well known theorem in Lorentzian geometry the longest timelike worldline between two given points is the unique geodesic line without points conjugate to the initial point on the segment joining the two points. We calculate the proper times for static twins, for twins moving on a circular orbit (if it is a geodesic) around a centre of symmetry and for twins travelling on outgoing and ingoing radial timelike geodesics. We show that the twins on the radial geodesic worldlines are always the oldest ones and we explicitly find the conjugate points (if they exist) outside the relevant segments. As it is of its own mathematical interest, we find general Jacobi vector fields on the geodesic lines under consideration. In the first part of the work we investigate Schwarzschild geometry.
description: 18 pages, paper accepted for publication in Gen. Rel. Grav
title: Inuit understandings of space: an oral historical and GIS approach to toponyms with knowledge holders in Hopedale, Nunatsiavut
Creators: name: Robinson, Sarah Laureen
Publisher: name: Memorial University of Newfoundland
Year: 2022

description: The objective of this research is to provide resources for culturally meaningful, placebased communication of toponyms surrounding Hopedale, Nunatsiavut, including Traditional Knowledge and Oral History regarding these places. By interviewing Elders and Knowledge Holders in Hopedale and on the land, information and memories about toponyms were shared that helped contribute to the creation of an interactive website and an accessible book summarizing the interviews for the community. By looking beyond place names as a dot on a map, a thorough and relational exploration of the history behind toponyms honours the validity of Indigenous ways of understanding past landscapes and encourages local archaeological learning. These different understandings of place are important for the formation of Inuit identity and community connections in Nunatsiavut, fostering understanding that Inuit identity is intrinsically connected to the idea of being and becoming within a geography. A fundamental part of this research is to step away from Western ontologies of landscape in order to understand Inuit history and place in a culturally relevant way.
Participation of grasses (Poaceae) in spontaneous development of plant cover on the edges of gravel excavation
Creators: name: Sierka, Edyta
Publisher: name: figshare
Year: 2021
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60202 Community Ecology (excl. Invasive Species Ecology)
subject: 50104 Landscape Ecology
subject: FOS: Earth and related environmental sciences

description: Sierka, E. and Babczyńska-Sendek, B. 2013. Participation of grasses (Poaceae) in spontaneous development of plant cover on the edges of gravel excavation. Fragmenta Floristica et Geobotanica Polonica vol. 20, No. 2, 285-301.