cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Identification of fatty acid metabolism-related lncRNAs in the prognosis and immune microenvironment of colon adenocarcinoma
Creators: name: Wu, Shuang
name: Gong, Yuzhu
name: Chen, Jianfang
name: Zhao, Xiang
name: Qing, Huimin
name: Dong, Yan
name: Li, Sisi
name: Li, Jianjun
name: Wang, Zhe
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 1. Supplementary Fig. S1: Workflow and TME features of C1 and C2 subtypes in GSE17538 dataset. A Work flow chart. B Estimated proportions of 24 immune cells. C Stromal score, immune score and ESTIMATE score calculated by ESTIMTAE analysis. D The expression of immune checkpoints in two subtypes. E, F T cell dysfunction and exclusion score calculated by TIDE analysis. Wilcoxon test was conducted.
A minority view on the majority: A personal meeting summary on the explosion mechanism of supernovae
Creators: name: Soker, Noam
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: In the meeting SN 1987A 30 years later, I presented my minority view that the majority (or even all) of core collapse supernovae (CCSNe) are driven by jets rather than by neutrinos, and that the majority of type Ia supernovae (SN Ia) reach their explosion via the core degenerate scenario. New simulations presented at the meeting did not achieve an explosion of CCSNe. I critically examine other arguments that where presented in support of the neutrino-driven model, and present counter arguments that support the jet-driven explosion mechanism. The jets operate via a negative jet feedback mechanism (JFM). The negative feedback mechanism explains the explosion energy being several times the binding energy of the core in most CCSNe. At the present time when we do not know yet what mechanism explodes massive stars and we do not know yet what evolutionary route leads white dwarfs to explode as SN Ia, we must be open to different ideas and critically examine old notions.
description: Submitted to SN 1987A 30 years later, Proceedings IAU Symposium No. 331, eds. Renaud, M. et al
title: Identification of myeloid cell populations at sites of laser-induced choroidal neovascularization by single-cell profiling
Creators: name: Schlecht, Anja
name: Wieghofer, P.
name: Zhang, P.
name: Bonvea, S.
name: Gruber, M.
name: Sankowski, R.
name: Schlunck, G.
name: Agostini, H.
name: Prinz, M.
name: Lange, C.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Myeloid cells (MC), such as resident microglia (MG) and infiltrating blood-derived monocytes (MO), are key players in the formation of choroidal neovascularization (CNV). However, the specific discrimination between MG and MO is challenging and the precise function of MG during CNV development[for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
Photo induced eosin-Y catalyzed synthesis and molecular docking studies of 5,5-diphenylimidazolidine-2,4-dione
Creators: name: Garima, Km
name: Kumar, Rohit
name: Srivastava, Vishal
name: Singh, Praveen Pratap
name: Singh, Pravin Kumar
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: One-pot photo induced eosin-Y catalyzed, green approach for the synthesis of 5,5-diphenylimidazolidine-2,4-dione (Phenytoin) has been developed. The reaction proceeded smoothly, for a wide range of benzil and urea/thiourea derivatives as cheap and eco friendly reagents with high reactivity and good selectivity in DMSO as green solvent at room temperature in good to excellent yields. Biological studies such as drug-likeness and molecular docking have been conducted on the synthesized compounds, some of the compounds showed appreciable activity with least binding energy.
title: Physiologische Grundlagen und Entstehung der OAE
Creators: name: Gummer, Anthony
name: Zelle, Denis
name: Dalhoff, Ernst
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Eine Langfassung des Beitrags erhalten Sie hier: [link:https://www.dga-ev.com/fileadmin/dga2019/site/data/final/0206.pdf*https://www.dga-ev.com/fileadmin/dga2019/site/data/final/0206.pdf[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 22. Jahrestagung der Deutschen Gesellschaft für Audiologie
Ultrafast X-ray Diffraction Thermometry Measures the Influence of Spin Excitations on the Heat Transport through nanolayers
Creators: name: Koc, A.
name: Reinhardt, M.
name: von Reppert, A.
name: Leitenberger, W.
name: Dumesnil, K.
name: Gaal, P.
name: Zamponi, F.
name: Bargheer, M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We investigate the heat transport through a rare earth multilayer system composed of Yttrium (Y), Dysprosium (Dy) and Niobium (Nb) by ultrafast X-ray diffraction. This is an example of a complex heat flow problem on the nanoscale, where several different quasi-particles carry the heat. The Bragg peak positions of each layer represent layer-specific thermometers that measure the energy flow through the sample after excitation of the Y top-layer with fs-laser pulses. In an experiment-based analytic solution to the nonequilibrium heat transport problem, we derive the individual contributions of the spins and the coupled electron-lattice system to the heat conduction. The full characterization of the spatiotemporal energy flow at different starting temperatures reveals that the spin excitations of antiferromagnetic Dy speed up the heat transport into the Dy layer at low temperatures, whereas the heat transport through this layer and further into the Y and Nb layers underneath is slowed down. The experimental findings are compared to the solution of the heat equation using macroscopic temperature-dependent material parameters without separation of spin- and phonon contributions to the heat. We explain, why the simulated energy density matches our experiment-based derivation of the heat transport, although the simulated thermoelastic strain in this simulation is not even in qualitative agreement.
Stakeholder engagement in water resource management: a systematic review of definitions, practices, and outcomes
Creators: name: Whitley, Hannah
name: Engle, Elyzabeth W.
name: Brasier, Kathryn J.
name: Eaton, Weston M.
name: Burbach, Mark E.
name: Fowler, Lara B.
name: Anariba, Sara Bonilla
name: Butzler, Emma
name: Dixon, Kathryn
name: Chaudhary, Anil Kumar
name: Whitmer, Walt
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: In the past three decades, a paradigm shift has elevated stakeholder engagement in natural resource governance, emphasizing collaborative approaches for effective decision-making. While academic literature increasingly endorses engagement methods, a gap persists in our knowledge of the methods and outcomes of such processes. To address this disparity, we systematically reviewed 261 peer-reviewed studies on stakeholder engagement in water resource management from 2000 to 2019. Analyses find that data-driven studies of engagement processes and outcomes from engagement processes are limited in the peer-reviewed literature. Our findings underscore the need for consistent vocabulary and theoretical frameworks and increased empirical evaluation to enhance our understanding of stakeholder engagement processes and outcomes in water resource management. We conclude by discussing the implications of these findings and synthesizing the methods suggested by the general literature for creating more inclusive, replicable, and impactful engagement-related research and practice in the future.
title: Otoakustische Emissionen – Messung und Interpretation der OAE im Gehörgang
Creators: name: Mauermann, Manfred
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Otoakustische Emissionen (OAE) sind Schallaussendungen des Innenohres, die im geschlossenen Gehörgang mit geeigneten Sondenmikrofonen messbar sind. Die Auslösbarkeit von OAE durch geeignete akustische Stimulation spiegelt im hohen Maße den Zustand der äußeren Haarsinneszellen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 22. Jahrestagung der Deutschen Gesellschaft für Audiologie
HST Hα grism spectroscopy of ROLES: a flatter low-mass slope for the z~1 SSFR--mass relation
Creators: name: Ramraj, Riona
name: Gilbank, David G.
name: Blyth, Sarah-Louise
name: Skelton, Rosalind E.
name: Glazebrook, Karl
name: Bower, Richard G.
name: Balogh, Michael L.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present measurements of star formation rates (SFRs) for dwarf galaxies (M*~10^8.5 Msun ) at z~1 using near-infrared slitless spectroscopy from the Hubble Space Telescope (HST) by targetting and measuring the luminosity of the Hα emission line. Our sample is derived from the Redshift One LDSS3 Emission Line Survey (ROLES), which used [O II]λ 3727 as a tracer of star formation to target very low stellar masses down to very low SFRs (~0.1 Msun yr^-1) at this epoch. Dust corrections are estimated using SED-fits and we find, by comparison with other studies using Balmer decrement dust corrections, that we require a smaller ratio between the gas phase and stellar extinction than the nominal Calzetti relation, in agreement with recent findings by other studies. By stacking the WFC3 spectra at the redshifts obtained from ground-based [O II] detections, we are able to push the WFC3 spectra to much lower SFRs and obtain the most complete spectroscopic measurement of the low mass end of the SSFR--mass relation to date. We measure a flatter low mass power law slope (-0.47 +/- 0.04) than found by other (shallower) Hα-selected samples (\approx -1), although still somewhat steeper than that predicted by the EAGLE simulation (-0.14 +/- 0.05), hinting at possible missing physics not modelled by EAGLE or remaining incompleteness for our Hα data.
description: MNRAS accepted, 17 pages, 13 figures
Additional file 8: of The insect pathogenic bacterium Xenorhabdus innexi has attenuated virulence in multiple insect model hosts yet encodes a potent mosquitocidal toxin
Creators: name: Il-Hwan Kim
name: Aryal, Sudarshan
name: Aghai, Dariush
name: ĂNgel Casanova-Torres
name: Hillman, Kai
name: Kozuch, Michael
name: Mans, Erin
name: Mauer, Terra
name: Ogier, Jean-Claude
name: Ensign, Jerald
name: Gaudriault, Sophie
name: Goodman, Walter
name: Goodrich-Blair, Heidi
name: Adler Dillman
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: A. domesticus infected with S. scapterisci. (PDF 5505Â kb)
Effects of Implementing an Enhanced Recovery After Cardiac Surgery Protocol with On-Table Extubation on Patient Outcome and Satisfaction—A Before–After Study
Creators: name: Werner, Adelina
name: Conrads, Hannah
name: Rosenberger, Johanna
name: Creutzenberg, Marcus
name: Graf, Bernhard
name: Foltan, Maik
name: Blecha, Sebastian
name: Stadlbauer, Andrea
name: Floerchinger, Bernhard
name: Tafelmeier, Maria
name: Arzt, Michael
name: Schmid, Christof
name: Bitzinger, Diane
Publisher: name: Universität Regensburg
Year: 2025
Subjects: subject: enhanced recovery after surgery (ERAS); on-table extubation; elective cardiac surgery; cardiac anesthesia; nausea and vomiting; postoperative cognitive dysfunction; patient satisfaction
subject: 610 Medizin

description: Background/Objectives: Enhanced recovery after surgery (ERAS) protocols aim to improve clinical outcomes, shorten hospital length of stay (LOS), and reduce costs through a multidisciplinary perioperative approach. Although introduced in colorectal surgery, they are less established in cardiac surgery, especially in combination with on-table extubation (OTE). This study evaluates the impact of a novel ERAS concept with OTE (RERACS) in elective aortic-valve-replacement and coronary bypass surgery. Methods: In a monocentric study, we compared a prospective RERACS-group (n = 114) to a retrospective control group (n = 119) (TRIAL Registration (DRKS00031402). The RERACS concept contained multiple perioperative treatment measures such as respiratory training, short fasting, and OTE. The control group received standard care. Results: Primary endpoint: postoperative LOS. Secondary measurements: length of postoperative vasoactive drug support, duration of mechanical ventilation, complication rate, and patient satisfaction on the second postoperative day. RERACS patients showed significantly shorter postoperative length of stay (ICU: 40 ± 34 h vs. 56 ± 51 h, p = 0.005; hospital: 9 ± 4 d vs. 11 ± 6 d, p = 0.028), lower nosocomial infection rates (24% vs. 40%), fewer cases of postoperative cognitive dysfunction ((subsyndromal) delirium 40% vs. 57%), reduced nausea and vomiting (14.9% vs. 32.8%), and faster weaning from catecholamines (22 ± 30 h vs. 42 ± 48 h, p < 0.001), as well as high patient satisfaction. Conclusions: Our study indicated that an ERAS concept with OTE is safe and associated with faster and improved recovery, including lower catecholamine requirements, reduced LOS, and high patient satisfaction in low-risk cardiac surgery.
title: Rolle von DPOAE für die Untersuchung des Gehörs verschiedener Tiermodelle
Creators: name: Kössl, Manfred
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Distorsions-Produkt-otoakustische-Emissionen (DPOAE) sind Ausdruck nichtlinearer Eigenschaften von Gehörorganen. Bei Säugetieren ist der cochleäre Verstärkungs­mechanismen in den äußeren Haarzellen die Hauptquelle dieser Emissionen. DPOAE sind sehr gut geeignet, schnell[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 22. Jahrestagung der Deutschen Gesellschaft für Audiologie
Direct observation of the Higgs amplitude mode in a two-dimensional quantum antiferromagnet near the quantum critical point
Creators: name: Hong, Tao
name: Matsumoto, Masashige
name: Qiu, Yiming
name: Chen, Wangchun
name: Gentile, Thomas R.
name: Watson, Shannon
name: Awwadi, Firas F.
name: Turnbull, Mark M.
name: Dissanayake, Sachith E.
name: Agrawal, Harish
name: Toft-Petersen, Rasmus
name: Klemke, Bastian
name: Coester, Kris
name: Schmidt, Kai P.
name: Tennant, David A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Spontaneous symmetry-breaking quantum phase transitions play an essential role in condensed matter physics. The collective excitations in the broken-symmetry phase near the quantum critical point can be characterized by fluctuations of phase and amplitude of the order parameter. The phase oscillations correspond to the massless Nambu$-$Goldstone modes whereas the massive amplitude mode, analogous to the Higgs boson in particle physics, is prone to decay into a pair of low-energy Nambu$-$Goldstone modes in low dimensions. Especially, observation of a Higgs amplitude mode in two dimensions is an outstanding experimental challenge. Here, using the inelastic neutron scattering and applying the bond-operator theory, we directly and unambiguously identify the Higgs amplitude mode in a two-dimensional S=1/2 quantum antiferromagnet C$_9$H$_{18}$N$_2$CuBr$_4$ near a quantum critical point in two dimensions. Owing to an anisotropic energy gap, it kinematically prevents such decay and the Higgs amplitude mode acquires an infinite lifetime.
description: 12 pages, 4 figures in the main text+3 figures in Supplementary Information
Catalytic synthesis of flavanone without stirring or heating
Creators: name: Shigematsu, Karin
name: Toriyama, Masaharu
name: Miura, Motofumi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: We developed a new approach for the synthesis of flavanone from chalcones without electrical energy, such as stirring or heating, by using a cesium fluoride–crown ether complex. This “zero electrical energy reaction” is a new category of reaction that has the potential to replace the general organic reaction.
IFAD RESEARCH SERIES 58 Investing in rural youth in the Asia and the Pacific region
Creators: name: Briones, Roehlano
name: Briones, Roehlano
Publisher: name: Unknown
Year: 2019
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Agricultural Finance
subject: Community/Rural/Urban Development
subject: Consumer/Household Economics
subject: Crop Production/Industries
subject: Financial Economics
subject: Gender
subject: financial inclusion
subject: education
subject: rural youth

description: This paper characterizes the structural and rural transformation of the Asia and the Pacific region (APR), highlighting the implications for rural youth opportunities and challenges, and identifying and elaborating on the characteristics, opportunities and challenges related to rural youth inclusion. Nearly half of the population in Asia is urban, with the proportion projected to rise to 59 per cent by 2035. Except for China, the majority of youth still reside in rural areas. Youth labour force participation is higher in rural than urban areas, and for males than females. Rural youth in countries with low structural transformation and low rural transformation continue to rely on agriculture for employment; in countries with high levels of transformation, a majority of rural youth are now employed outside agriculture (though it is still the biggest contributor to rural youth employment). About one fifth of youth in Asia are not in education, employment or training. More than 86 per cent of employed youth in Asia and the Pacific are in the informal sector, greater than the proportion of informal employment among adult workers
CSCCE Tech Tip Sheet: Using GitHub for community management
Creators: name: Pratt, Katie
name: Kalderimis, Alex
name: Bellini Saibene, Yanina
name: Garside, Danny
name: Koehler Leman, Julia
name: Sane, Maneesha
name: Steele, Anne Lee
name: Verma, Sanket
name: Lescak, Emily
name: Crall, Alycia
name: Woodley, Lou
Publisher: name: Zenodo
Year: 2024
Subjects: open-source
open-source tools trials outputs
CSCCE

description: In 2023, CSCCE hosted a series of community “Tools Trials” that focused on tools commonly used for community management in open-source and open-source-supporting communities. The goal of the series - which consisted of several live webinars with Q&A and this accompanying tip sheet collection - was to share existing knowledge and provide any scientific community manager with options about tools and use cases they could explore further.

One of the most commonly used tools by open-source communities is GitHub. In this tip sheet, we’ve curated some basic information about GitHub and how you can get started on the platform as a scientific community manager. 

About CSCCE

The Center for Scientific Collaboration and Community Engagement (CSCCE) champions the importance of human infrastructure for effective collaboration in STEM. We provide training and support for the people who make scientific collaborations succeed at scale - and we also research the impact of these emerging roles. Find out more about us on our website: CSCCE.org
Additional file 2 of Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence
Creators: name: Ayers, Jacob I.
name: Xu, Guilian
name: Dillon, Kristy
name: Lu, Qing
name: Chen, Zhijuan
name: Beckman, John
name: Moreno-Romero, Alma K.
name: Zamora, Diana L.
name: Galaleldeen, Ahmad
name: Borchelt, David R.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 2. This file contains all Supplementary Material, including Supplementary Tables S1-S3 and Supplementary Figures S1-S15.
An alternative total synthesis of Aigialomycin D
Creators: name: S, Sudhakar D G
name: Reddy, Venkata Ramana
name: Syed, Tasqeeruddin
name: Sridhar, Gattu
name: Alapati, Srinivasa Rao
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Aigialomycin D, a 14-membered benzannulated macrolactone, was synthesized in a simple, efficient and stereoselective approach using inexpensive and commonly accessible starting materials. The main steps in this convergent synthesis are Corey-Fuchs reaction, Yamaguchi esterification and ring closing metathesis (RCM).
title: OAE in der Klinik – Einsatz im klinischen Alltag und Wertigkeit spezieller Indikationen
Creators: name: Hoth, Sebastian
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Ausgangspunkt: Die Entdeckung der otoakustischen Emissionen (OAE) liegt 40 Jahre zurück, ihre Einführung in Klinik und Praxis 30 Jahre und die Zeit der größten Intensität in der wissenschaftlichen Erkundung ihrer Anwendungsmöglichkeiten etwa 20 Jahre. Als Substrat dieser[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 22. Jahrestagung der Deutschen Gesellschaft für Audiologie
Novel esters derived from 4-hydroxychalcones as potential sunscreens with antimicrobial action
Creators: name: de Sousa, Abraão Pinheiro
name: da Silva Souza, Helivaldo Diógenes
name: Almeida-Júnior, Alexandre
name: da Silva, Marcelo Felipe Rodrigues
name: Cordeiro, Laísa Vilar
name: de Oliveira Lima, Edeltrudes
name: Fiss, Gabriela Fehn
name: de Athayde-Filho, Petrônio Filgueiras
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Ten novel 4-esterchalcones, licochalcone analogues, were strategically synthesized to study the effect of electro-donating or electro-withdrawing substituents in the aryl enone moiety on their pharmacological and photoprotective properties. 4-Esterchalcones had their drug-like character evaluated, which demonstrated positive characteristics for the development of novel drug candidates. In the in vitro antimicrobial evaluation, isovaleryl 4-esterchalcones showed activity against strains of Staphylococcus aureus, Candida albicans and C. tropicalis with minimum inhibitory concentration (MIC) in the range of 2.64-3.32 µmol mL−1, and the isobutyryl 4-esterchalcone 5d (4’-Br) presented antimicrobial activity against all strains tested, with a MIC of 2.74 µmol mL−1. In the UV-Vis study, λmax were observed at 312-327 nm, the UVB range, mainly. The best SPF-UVB results ranged from 18.04 to 21.06, with high εmax values, indicating that 4-esterchalcones have the potential to act as sunscreens. Furthermore, along with the environmental concern, halogenated compounds demonstrated slightly toxic on Artemia salina.
title: Effect of long-term inflammation on viability and function of RPE cells
Creators: name: Klettner, Alexa
name: Winkelmann, K.
name: Brinkmann, A.
name: Käckenmeister, T.
name: Roider, J.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Degenerative ocular disorders like age-related macular degeneration (AMD) may induce long-term pro-inflammatory signals on retinal pigment epithelial (RPE) cells. In this study, we investigated the effect of long term treatment of RPE cells with agonists of toll-like receptor (TLR)3 (Poly[for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
Trovos modernos en los que manifiesta un galán a su dama el mucho amor que le tiene: Digital edition
Creators: name: Leblanc Elina
Publisher: name: Zenodo
Year: 2024
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2024), led by professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
MOESM4 of Functional dissection of Drosophila melanogaster SUUR protein influence on H3K27me3 profile
Creators: name: Posukh, Olga
name: Maksimov, Daniil
name: Laktionov, Petr
name: Koryakov, Dmitry
name: Belyakin, Stepan
Publisher: name: figshare
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Developmental Biology

description: Additional file 4: Figure S2. Examples of SSRs that are not under-replicated in salivary gland of wildÂ type strain. The color code and legend are the same as in Fig.Â 1a. H3K27me3 profiles are presented as quantile normalized log2(IP/inp) values.
title: Microglia as important part of the retina: Its role in AMD
Creators: name: Langmann, Thomas
name: Wolf, A.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: This talk highlights the role of key immune pathways in the pathophysiology of major retinal degenerative diseases including age-related macular degeneration. We will first discuss the mechanisms how loss of retinal homeostasis evokes an unbalanced immune reaction involving responses of local microglia[for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
DotDFS: A Grid-based high-throughput file transfer system
Creators: name: Poshtkohi, Alireza
name: Ghaznavi-Ghoushchi, M. B.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences
subject: C.2.4; C.2.2; C.2.5; C.4; D.1.3; D.2.12; D.3; D.4.3; D.4.4; D.4.8; E.5; D.4.6

description: DotGrid platform is a Grid infrastructure integrated with a set of open and standard protocols recently implemented on the top of Microsoft .NET in Windows and MONO .NET in UNIX/Linux. DotGrid infrastructure along with its proposed protocols provides a right and solid approach to targeting other platforms, e.g., the native C/C++ runtime. In this paper, we propose a new file transfer protocol called DotDFS as a high-throughput distributed file transfer component for DotGrid. DotDFS introduces some open binary protocols for efficient file transfers on current Grid infrastructures. DotDFS protocol also provides mechanisms for multiple file streams to gain high-throughput file transfer similar to GridFTP protocol, but by proposing and implementing a new parallel TCP connection-oriented paradigm. In our LAN tests, we have achieved better results than Globus GridFTP implementation particularly in multiple TCP streams and directory tree transfers. Our LAN experiences in memory-to-memory tests show that DotDFS accesses to the 94% bottleneck bandwidth while GridFTP is accessing 91%. In LAN disk-to-disk tests, comparing DotDFS protocol with GridFTP protocol unveils a set of interesting and technical problems in GridFTP for both the nature of the protocol and its implementation by Globus. In the WAN experimental studies, we propose a new idea for analytical modeling of file transfer protocols like DotDFS inspired by sampling, experimentation and mathematical interpolation approaches. The cross-platform and open standard-based features of DotDFS provide a substantial framework for unifying data access and resource sharing in real heterogeneous Grid environments.
description: 28 pages, 21 figures
Additional file 13 of The dissection of R genes and locus Pc5.1 in Phytophthora capsici infection provides a novel view of disease resistance in peppers
Creators: name: Du, Jin-Song
name: Hang, Lin-Feng
name: Hao, Qian
name: Yang, Hai-Tao
name: Ali, Siyad
name: Badawy, Radwa Salah Ezaat
name: Xu, Xiao-Yu
name: Tan, Hua-Qiang
name: Su, Li-Hong
name: Li, Huan-Xiu
name: Zou, Kai-Xi
name: Li, Yu
name: Sun, Bo
name: Lin, Li-Jin
name: Lai, Yun-Song
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 13. Protein structure and gene structure of NBS-ARC genes with complete NBS-ARC domains.
title: Transcriptomic characterization of human choroidal neovascular membranes identifies calprotectin as a novel biomarker for patients with AMD
Creators: name: Lange, Clemens
name: Schlecht, A.
name: Boneva, S.
name: Wolf, J.
name: Zhang, P.
name: Prinz, G.
name: Horres, R.
name: Bucher, F.
name: Auw-Haedrich, C.
name: Hansen, L.
name: Stahl, A.
name: Hilgendorf, I.
name: Agostini, H.
name: Wieghofer, P.
name: Schlunck, G.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Purpose: Although genome-wide association studies, animal models, and cell culture systems have yielded important insights into the pathogenesis of neovascular age-related macular degeneration (nAMD), the underlying molecular pathways remain ill defined. The current study aims to explore the transcriptome[for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
The SAGEX Review on Scattering Amplitudes, Chapter 5: Analytic Bootstraps for Scattering Amplitudes and Beyond
Creators: name: Papathanasiou, Georgios
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2022
Subjects: algebra, cluster
gauge field theory, Yang-Mills
bootstrap
scattering amplitude
Feynman graph
analytic properties
kinematics
structure
field theory
form factor
supersymmetry

description: One of the main challenges in obtaining predictions for collider experiments from perturbative quantum field theory, is the direct evaluation of the Feynman integrals it gives rise to. In this chapter, we review an alternative bootstrap method that instead efficiently constructs physical quantities by exploiting their analytic structure. We present in detail the setting where this method has been originally developed, six- and seven-particle amplitudes in the large-color limit of $\mathcal{N}=4$ super Yang-Mills theory. We discuss the class of functions these amplitudes belong to, and the strong clues mathematical objects known as cluster algebras provide for rendering this function space both finite and of relatively small dimension at each loop order. We then describe how to construct this function space, as well as how to locate the amplitude inside of it with the help of kinematic limits, and apply the general procedure to a concrete example: The determination of the two-loop correction to the first nontrivial six-particle amplitude. We also provide an overview of other areas where the realm of the bootstrap paradigm is expanding, including other scattering amplitudes, form factors and Feynman integrals, and point out the analytic properties of potentially wider applicability that it has revealed.
Interplay of nematic and magnetic orders in FeSe under pressure
Creators: name: Scherer, Daniel D.
name: Jacko, Anthony
name: Friedrich, Christoph
name: Sasioglu, Ersoy
name: Blugel, Stefan
name: Valenti, Roser
name: Andersen, Brian M.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We offer an explanation for the recently observed pressure-induced magnetic state in the iron-chalcogenide FeSe based on \textit{ab initio} estimates for the pressure evolution of the most important Coulomb interaction parameters. We find that an increase of pressure leads to an overall decrease mostly in the nearest-neighbor Coulomb repulsion, which in turn leads to a reduction of the nematic order and the generation of magnetic stripe order. We treat the concomitant effects of band renormalization and the induced interplay of nematic and magnetic order in a self-consistent way and determine the generic topology of the temperature-pressure phase diagram, and find qualitative agreement with the experimentally determined phase diagram.
description: 13 pages, 6 figs
title: Impaired function of the lipid transporters ABCA1 and ABCG1 in the RPE leads to an AMD-like phenotype in mice
Creators: name: Grimm, Christian
name: Storti, F.
name: Hornemann, T.
name: den Hollander, A.
name: Maugeais, C.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Since the RPE has to internalize large amounts of shed tips of photoreceptor outer segments every day, it requires an efficient intracellular system to handle, metabolize and/or dispose lipids. Several genes involved in lipid metabolism including the ATP-binding cassette transporter A1 (ABCA1) [for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
Trovos modernos en los que manifiesta un galán a su dama el mucho amor que le tiene: Digital edition
Creators: name: Leblanc Elina
Publisher: name: Zenodo
Year: 2021
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2022), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Trovos modernos en los que manifiesta un galán a su dama el mucho amor que le tiene: Digital edition
Creators: name: Leblanc Elina
Publisher: name: Zenodo
Year: 2022
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2022), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
title: Elovanoids are novel photoreceptor survival signals relevant to AMD
Creators: name: Bazan, Nicolas
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background: The RPE and PRC relationship restores adversities to homeostasis. DHA is a membrane component necessary for vision that is decreased in AMD. The genetic ablation of Adiponectin Receptor 1 (AdipoR1) blocks DHA uptake, reduces phosphatidylcholine (PC)-containing Very Long Chain Polyunsaturated[for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
Solving the Uncapacitated Single Allocation p-Hub Median Problem on GPU
Creators: name: Benaini, Abdelhamid
name: Berrajaa, Achraf
name: Boukachour, Jaouad
name: Oudani, Mustapha
Publisher: name: arXiv
Year: 2017
Subjects: subject: Discrete Mathematics (cs.DM)
subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: A parallel genetic algorithm (GA) implemented on GPU clusters is proposed to solve the Uncapacitated Single Allocation p-Hub Median problem. The GA uses binary and integer encoding and genetic operators adapted to this problem. Our GA is improved by generated initial solution with hubs located at middle nodes. The obtained experimental results are compared with the best known solutions on all benchmarks on instances up to 1000 nodes. Furthermore, we solve our own randomly generated instances up to 6000 nodes. Our approach outperforms most well-known heuristics in terms of solution quality and time execution and it allows hitherto unsolved problems to be solved.
title: Meilensteine der Pädagogischen Audiologie: Von den Anfängen in Heidelberg bis heute
Creators: name: Bogner, Barbara
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Armin Löwe (1922-2001) hat 1959 die erste Pädoaudiologische Beratungsstelle in Heidelberg etabliert und war damit ein Wegbereiter für die pädagogische Kinderaudiometrie und die Hörgeräteversorgung bei Kindern. Seine Auffassung war in der damaligen Zeit revolutionär,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 22. Jahrestagung der Deutschen Gesellschaft für Audiologie
title: Objektive Maße bei Kindern mit Hörschädigung in der frühkindlichen Entwicklung – Fallbeispiele
Creators: name: Kral, Katrin
name: Lang-Roth, Ruth
name: Streicher, Barbara
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Schwerhörigkeit im Kindesalter ist verbunden mit der Frage nach der Prognose für die weitere sprachliche, kognitive und motorische Entwicklung. Es werden zwei Fallbeispiele aus der Studie zur "frühkindlichen Entwicklung bei Kindern mit einer Hörschädigung im[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 22. Jahrestagung der Deutschen Gesellschaft für Audiologie
title: 01_2758
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
title: Plausibilität zwischen den Ergebnissen der objektiven Audiometrie und der pädagogischen Audiologie in der CI-Rehabilitation
Creators: name: Streicher , Barbara
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die Versorgung von Kindern mit CI-Systemen beinhaltet ein multiprofessionelles Vorgehen. Die Verfahren der objektiven Messung wie evozierte Potentiale oder die Ableitung von telemetrischen Daten während der Anpassung suggerieren, dass die auditive Verarbeitung messtechnisch abgesichert[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 22. Jahrestagung der Deutschen Gesellschaft für Audiologie
title: The publication practices of scholars in one research intensive institution in Russia
Creators: name: Smirnova, Natalia
Publisher: name: The Open University
Year: 2024

description: This thesis contributes to the field of academic writing for publication by exploring publication practices of sixteen scholars at a university in Russia, a previously under-researched geopolity. With the dominance of English, the world of academic publishing has undergone significant changes; hence, this ethnographically-oriented study reports on the issues Russian scholars face because of these changes when publishing in Russian and English. The thesis pays attention to both text and context, combining interviews with the analysis of paired texts in English and Russian as well as paired text histories (THs).


The findings are presented in three ways. Firstly, findings grounded in scholars’ interviews highlight the experiences scholars face when they publish in two languages. Secondly, findings based on publication records and detailed CVs of these scholars indicate the key languages and publication output types in knowledge production. In knowledge circulation, findings based on a participant-generated corpus supported by interview accounts provide insights into why scholars choose to cite works written in a particular language in their Russian- and English-medium texts and across three disciplines. Finally, findings based on three paired THs make visible the role of literacy brokers and scholars’ agency in responding to their citation requests.

Overall, this thesis contributes to knowledge in four ways: 1) by extending the empirical evidence through documentation of issues surrounding publication practices of scholars working outside the ‘Anglophone centre’; 2) by illuminating the role of language choice in knowledge production and circulation; 3) by demonstrating the significance of brokering and specific ways in which what gets cited impacts knowledge circulation globally. A fourth and methodological contribution is a paired approach which allows the decentring of English in multilingual text production.
Additional file 7: of The insect pathogenic bacterium Xenorhabdus innexi has attenuated virulence in multiple insect model hosts yet encodes a potent mosquitocidal toxin
Creators: name: Il-Hwan Kim
name: Aryal, Sudarshan
name: Aghai, Dariush
name: ĂNgel Casanova-Torres
name: Hillman, Kai
name: Kozuch, Michael
name: Mans, Erin
name: Mauer, Terra
name: Ogier, Jean-Claude
name: Ensign, Jerald
name: Gaudriault, Sophie
name: Goodman, Walter
name: Goodrich-Blair, Heidi
name: Adler Dillman
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: X. innexi loci with genes predicted to encode T6SS components. (PDF 72Â kb)
Effects of soft interactions and bound mobility on diffusion in crowded environments: a model of sticky and slippery obstacles
Creators: name: Stefferson, Michael W.
name: Norris, Samantha A.
name: Vernerey, Franck J.
name: Betterton, Meredith D.
name: Hough, Loren E.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Quantitative Methods (q-bio.QM)
subject: Subcellular Processes (q-bio.SC)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Crowded environments modify the diffusion of macromolecules, generally slowing their movement and inducing transient anomalous subdiffusion. The presence of obstacles also modifies the kinetics and equilibrium behavior of tracers. While previous theoretical studies of particle diffusion have typically assumed either impenetrable obstacles or binding interactions that immobilize the particle, in many cellular contexts bound particles remain mobile. Examples include membrane proteins or lipids with some entry and diffusion within lipid domains and proteins that can enter into membraneless organelles or compartments such as the nucleolus. Using a lattice model, we studied the diffusive movement of tracer particles which bind to soft obstacles, allowing tracers and obstacles to occupy the same lattice site. For sticky obstacles, bound tracer particles are immobile, while for slippery obstacles, bound tracers can hop without penalty to adjacent obstacles. In both models, binding significantly alters tracer motion. The type and degree of motion while bound is a key determinant of the tracer mobility: slippery obstacles can allow nearly unhindered diffusion, even at high obstacle filling fraction. To mimic compartmentalization in a cell, we examined how obstacle size and a range of bound diffusion coefficients affect tracer dynamics. The behavior of the model is similar in two and three spatial dimensions. Our work has implications for protein movement and interactions within cells.
description: Submitted to Biophysical Journal