cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Improving fungicide-based management of Cercospora leaf spot in table beet in New York, USA
Creators: name: Pethybridge, Sarah J.
name: SARAH J. PETHYBRIDGE 0000-0003-3864-4293
name: Sharma, Sandeep
name: SANDEEP SHARMA
name: ZACHARIAH R. Hansen
name: ZACHARIAH HANSEN
name: Vaghefi, Niloofar
name: NILOOFAR VAGHEFI
name: Hanson, Linda E.
name: LINDA E. HANSON
name: Kikkert, Julie R.
name: JULIE R KIKKERT
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: Cercospora leaf spot (CLS), caused by Cercospora beticola Sacc., is the dominant foliar disease affecting the profitability of table beet production in New York, USA. The disease is controlled primarily with fungicides, but sustainability is critically threatened by strobilurin resistance within the C. beticola population and a limited suite of alternatives. This study evaluated the temporal dynamics of strobilurin resistance within the C. beticola population over three years, and quantified sensitivity to selected demethylation inhibitors (DMIs; propiconazole and difenoconazole) and succinate dehydrogenase inhibitors (SDHIs; fluopyram, penthiopyrad, boscalid and benzovindiflupyr). Resistance to azoxystrobin (EC50 > 0.2 µg mL−1) was prevalent and detected in all fields sampled in 2015 and 2016, and six of 10 fields in 2017. Within fields, the incidence of azoxystrobin-resistant isolates ranged between 4.8% and 70%. No significant differences were detected in the frequency of azoxystrobin-resistant isolates within populations from fields with conventional and organic practices in 2016 and 2017. Reduced sensitivity to propiconazole and difenoconazole was detected in less than 1% of isolates. The EC50 values for the SDHIs were higher than the maximum concentrations (≥ 20 µg mL−1) evaluated. Two small-plot replicated field trials were also conducted over two years to evaluate alternatives to the commercial standards, propiconazole and azoxystrobin. Two applications of benzovindiflupyr + difenoconazole and pydiflumetofen + difenoconazole significantly reduced CLS severity and epidemic progress compared with plots that received propiconazole and non-treated controls.
Strengthen causal models for better conservation outcomes for human well-being
Creators: name: Cheng, Samantha H.
name: McKinnon, Madeleine C.
name: Masuda, Yuta J.
name: Garside, Ruth
name: Jones, Kelly W.
name: Miller, Daniel C.
name: Pullin, Andrew S.
name: Sutherland, William J.
name: Augustin, Caitlin
name: Gill, David A.
name: Wongbusarakum, Supin
name: Wilkie, David
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: subject: Research Article
subject: Social sciences
subject: FOS: Social sciences
subject: Ecology and environmental sciences
subject: Biology and life sciences
subject: Medicine and health sciences
subject: Research and analysis methods

description: Funder: Arcadia Fund; funder-id: http://dx.doi.org/10.13039/100012088
description: Funder: National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care (CLAHRC) for the South West Peninsula (PenCLAHRC)
description: Background: Understanding how the conservation of nature can lead to improvement in human conditions is a research area with significant growth and attention. Progress towards effective conservation requires understanding mechanisms for achieving impact within complex social-ecological systems. Causal models are useful tools for defining plausible pathways from conservation actions to impacts on nature and people. Evaluating the potential of different strategies for delivering co-benefits for nature and people will require the use and testing of clear causal models that explicitly define the logic and assumptions behind cause and effect relationships. Objectives and methods: In this study, we outline criteria for credible causal models and systematically evaluated their use in a broad base of literature (~1,000 peer-reviewed and grey literature articles from a published systematic evidence map) on links between nature-based conservation actions and human well-being impacts. Results: Out of 1,027 publications identified, only ~20% of articles used any type of causal models to guide their work, and only 14 total articles fulfilled all criteria for credibility. Articles rarely tested the validity of models with empirical data. Implications: Not using causal models risks poorly defined strategies, misunderstanding of potential mechanisms for affecting change, inefficient use of resources, and focusing on implausible efforts for achieving sustainability.
Willingness to pay to reduce health costs associated with bushfire smoke
Creators: name: Chalak, Morteza
name: Burton, Michael
name: Chalak, Morteza
name: Burton, Michael
Publisher: name: Unknown
Year: 2016
Subjects: subject: Environmental Economics and Policy
subject: Willingness to pay
subject: altruism
subject: paternalistic
subject: bushfire smoke
subject: health

description: Invasion of gamba grass in Northern Territory increases fire fuel and bushfire smoke. Increase in bushfire smoke decreases air quality and have negative health impacts. The aim of this study is to assess people’s willingness pay in order to control bushfire smoke and reduce its health risks. We also aim to assess what part of their willingness to pay is derived from altruism. To do this, we form two versions of a survey. The first version aims to assess willingness to pay which may consist of both altruism and personal benefits. The framing tells the respondents to assume that increases in bushfire smoke will affect their own personal health. In the second version of the survey that aims to assess only altruism, respondents will be limited to those who do not have asthma. We tell these respondents that increase in bushfire smoke will only affect people with asthma. Visual aides were used to enhance risk comprehension. Results showed that analysing altruistic value is important when valuing environmental assets. Altruistic value of statistical life is calculated at $5000,000. We showed that distinguishing paternalistic and non-paternalistic altruism is important.48% of WTP was non-paternalistic altruism. Paternalistic altruism is estimated at $2600,000.
Optimization of zoospore production and inoculum concentration of Aphanomyces euteiches for resistance screening of pea and lentil
Creators: name: Nimllash T. Sivachandra Kumar
name: NIMLLASH T. SIVACHANDRA KUMAR
name: Cox, Laura
name: LAURA COX
name: Armstrong-Cho, Cheryl
name: CHERYL ARMSTRONG-CHO
name: Banniza, Sabine
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Plant Biology

description: Aphanomyces euteiches is an important root pathogen of several legume and forage crops worldwide. Disease management is challenging due to resilient oospores that can persist in the soil for long periods of time. Several research groups are working towards incorporating disease resistance into crop cultivars involving large-scale disease resistance screening and, for some crops, the use of molecular markers associated with quantitative trait loci for resistance. The refinement of laboratory protocols for efficient pathogen isolation, reliable and simple zoospore production, and a repeatable indoor screening assay are important tools needed to further research in this area. The standardization of these protocols among research groups would provide an efficient platform for research collaboration. The effect of different media and sporulation induction methods on zoospore production was assessed. The most effective and repeatable method of A. euteiches zoospore production involved culturing and incubation for 4 days on autoclaved wheat leaf segments placed on corn meal-yeast extract-phosphate buffer agar. Colonized wheat leaves were transferred into 100 mL of distilled water in 250 mL flasks and incubated at 100 rpm for 18 h at 24ºC to induce zoospore production. Five zoospore concentrations ranging from 100 to 10 000 zoospores mL−1 were evaluated using susceptible and partially resistant pea and lentil genotypes to optimize zoospore concentration for germplasm screening. The best differentiation of levels of resistance among lentil and pea genotypes was achieved with 1000 zoospores mL−1.
TRIM13 inhibits cell proliferation and induces autophagy in lung adenocarcinoma by regulating KEAP1/NRF2 pathway
Creators: name: Yu, Bo
name: Zhou, Yu
name: He, Jinxi
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Lung adenocarcinoma (LUAD) is the most common type of lung cancer. Tripartite motif 13 (TRIM13) is a member of TRIM protein family and is downregulated in multiple cancers, especially non-small cell lung cancers (NSCLC). In this study, we investigated anti-tumor mechanism of TRIM13 in non-small cell lung cancer tissues and cell lines. First, the mRNA and protein levels of TRIM13 in LUAD tissue and cells were measured. TRIM13 was overexpressed on LUAD cells to investigate the effects on cell proliferation, apoptosis, oxidative stress, p62 ubiquitination, and autophagy activation. Finally, mechanistic role of TRIM13 in regulating the Keap1/Nrf2 pathway was investigated. Results indicated that low level of TRIM13 mRNA and protein expression was found in LUAD tissue and cells. Overexpression of TRIM13 in LUAD cancer cells suppressed their proliferation, increased apoptosis, and oxidative stress, ubiquitinated p62, and activated autophagy via the RING finger domain of TRIM13. Furthermore, TRIM13 showed interaction with p62 and mediated its ubiquitination and degradation in LUAD cells. Mechanistically, TRIM13 exerted the tumor suppressor functions in LUAD cells by negatively regulating Nrf2 signaling and downstream antioxidants, which was further confirmed by in vivo data from xenografts. In conclusion, TRIM13 behaves like a tumor suppressor and triggers autophagy in LUAD cells by mediating p62 ubiquitination via KEAP1/Nrf2 pathway. Our findings provide a novel insight into targeted therapy plans for LUAD.
Europium Isotopic Abundances in Very Metal-poor Stars
Creators: name: Sneden, Christopher
name: Cowan, John J.
name: Lawler, James E.
name: Burles, Scott
name: Beers, Timothy C.
name: Fuller, George M.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Europium isotopic abundance fractions are reported for the very metal-poor, neutron-capture-rich giant stars CS 22892-052, HD 115444, and BD +17 3248. The abundance fractions, derived from analysis of several strong Eu II lines appearing in high-resolution spectra of these stars, are in excellent agreement with each other and with their values in the Solar System: fraction(\iso{Eu}{151}) ~= fraction(\iso{Eu}{153}) ~= 0.5. Detailed abundance studies of very metal-poor stars have previously shown that the total elemental abundances of stable atoms with atomic numbers z >= 56 typically match very closely those of a scaled solar-system r-process abundance distribution. The present results for the first time extend this agreement to the isotopic level.
description: 13 pages, 3 figures; To appear in ApJ Letters
Symptoms and distribution of blossom blight in alfalfa seed production on the Canadian Prairies
Creators: name: B. D. Gossen
name: R. J. Howard
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Plant Biology
subject: Computational Biology

description: Surveys of alfalfa (Medicago sativa L.) seed production fields on the Canadian Prairies from 1993 to 2017 demonstrated that epidemics of blossom blight caused by Botrytis cinerea Pers. and Sclerotinia sclerotiorum (Lib.) de Bary developed almost every year at some location(s). Blossom blight symptoms were prominent when epidemics were severe, but more difficult to identify when present at low levels, which likely contributes to the infrequent reporting of blossom blight in alfalfa seed production. Epidemics were observed across the entire region, from the Peace River region of northern Alberta to southern Manitoba, consistently associated with relatively cool, wet weather conditions. The widespread nature of blossom blight on alfalfa in the years following its initial diagnosis in Canada in 1993, together with the ubiquitous distribution of the pathogens involved on other crops, indicated that blossom blight was almost certainly present on alfalfa seed crops on the Canadian Prairies for many years before the initial identification. It appears likely that blossom blight continues to cause yield loss at some locations in most years.
Rhigopsidius tucumanus Heller 1906
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Rhigopsidius
Rhigopsidius tucumanus

description: Rhigopsidius tucumanus Heller, 1906
 Rhigopsidius tucumanus Heller, 1906: 8 (type locality: Argentina: Tucumán; type material: H: SMTD).
 Immature stages. Larva (Marvaldi, 1998).
 Host plants. Solanum tuberosum L. (Solanaceae) (Marvaldi, 1998).
 Distribution. Northwestern Argentina (Morrone and Loiácono, 1992).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 56, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
AN- OVERVIEW- FORMULATION AND EVALUATION OF FACE SERUM BY USING LINUM USITATISSIMUM (FLAXSEED)
Creators: name: Ashika. M*, Binsha Fathima. S*, Deena Femi I. A*, Dr. Shaji Selvin C. D*, Kaveri B T *,  Dr. Prasobh G R*
Publisher: name: Zenodo
Year: 2025

description: The term "cosmetic," which once referred to appearance, now has a broader connotation. They concentrate on keeping the 'appearance' of external bodily surfaces such as skin, hair, and teeth, as well as eliminating odors with deodorization or perfume. They were also designed to be rubbed, poured, sprinkled, or sprayed on, injected into, or otherwise applied to any region of the human body in order to cleanse, beautify, promote attractiveness, or change appearance. Herbal cosmetics, also known as botanical cosmetics or Phyto-cosmetics, are personal care products that utilize herbs, plants, and other natural ingredients to promote beauty, health, and well-being. A face serum is a concentrated skincare product that penetrates active ingredients deep into the skin, addressing a variety of skin issues like aging, acne, and hyperpigmentation. Hydrate and plump the skin, eliminate fine lines and wrinkles, increase skin elasticity and firmness, brighten and level out skin tone, minimize pores and acne, and shield the skin from environmental stresses and harm. The aim of the study was to formulate and evaluate the face serum incorporated with the flaxseed.

Keywords: Cosmetics, Charactertics, face serum, flaxseed, evaluation
Steriphus Erichson 1842
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Steriphus

description: Steriphus Erichson, 1842
 Steriphus Erichson, 1842: 190 (type species: S. solidus Erichson, 1842, by indication, monotypy) (in Molytinae); Lacordaire, 1863: 346 (transferred to to Cylydrorhininae); Alonso-Zarazaga and Lyal, 1999: 142 (transferred to Rhythirrhinini: Rhythirrhinina); Oberprieler, 2010: 14 (transferred to Listroderini).
 Desiantha Pascoe, 1870: 193 (type species: D. caudata Pascoe, 1870, subsequent designation by Zimmerman, 1994: 697); Kuschel, 1962: 75 (in Listroderini); Kuschel, 1964: 458 (in Rhyparosominae); Zimmerman, 1990: 81 (= Steriphus).
 Brexius Pascoe, 1870: 201 (type species: B. murinus Pascoe, 1870, subsequent designation by Zimmerman, 1994: 697); Marshall, 1943: 118 (= Desiantha).
 Dryopais Broun, 1885: 387 (type species: D. variabilis Broun, 1885, by indication, monotypy); Kuschel, 1964: 458 (from Erirhininae to Rhyparosominae); Kuschel, 1972: 282 (= Desiantha).
 Xerostygnus Broun, 1903: 79 (type species: X. binodulus Broun, 1903, by indication, monotypy); Kuschel, 1962: 75 (in Listroderini); Kuschel, 1964: 458 (from Erirhininae to Rhyparosominae); Kuschel, 1972: 282 (= Desiantha).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 57, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Genomic structure and transcript analysis of the Rapid Alkalinization Factor (RALF) gene family during host-pathogen crosstalk in Fragaria vesca and Fragaria x ananassa strawberry
Creators: name: Negrini, Francesca
name: O’Grady, Kevin
name: Hyvönen, Marko
name: Folta, Kevin M.
name: Baraldi, Elena
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Research Article
Research and analysis methods
Biology and life sciences
Medicine and health sciences

description: Rapid Alkalinization Factors (RALFs) are cysteine-rich peptides ubiquitous within plant kingdom. They play multiple roles as hormonal signals in diverse processes, including root elongation, cell growth, pollen tube development, and fertilization. Their involvement in host-pathogen crosstalk as negative regulators of immunity in Arabidopsis has also been recognized. In addition, peptides homologous to RALF are secreted by different fungal pathogens as effectors during early stages of infection. Previous studies have identified nine RALF genes in the diploid strawberry (Fragaria vesca) genome. This work describes the genomic organization of the RALF gene families in commercial octoploid strawberry (Fragaria × ananassa) and the re-annotated genome of F. vesca, and then compares findings with orthologs in Arabidopsis thaliana. We reveal the presence of 15 RALF genes in F. vesca genotype Hawaii 4 and 50 in Fragaria x ananassa cv. Camarosa, showing a non-homogenous localization of genes among the different Fragaria x ananassa subgenomes. Expression analysis of Fragaria x ananassa RALF genes upon infection with Colletotrichum acutatum or Botrytis cinerea showed that FanRALF3-1 was the only fruit RALF gene upregulated after fungal infection. In silico analysis was used to identify distinct pathogen inducible elements upstream of the FanRALF3-1 gene. Agroinfiltration of strawberry fruit with deletion constructs of the FanRALF3-1 promoter identified a 5’ region required for FanRALF3-1 expression in fruit, but failed to identify a region responsible for fungal induced expression.
Determination of the primordial helium abundance based on NGC 346 an HII region of the Small Magellanic Cloud
Creators: name: Valerdi, Mabel
name: Peimbert, Antonio
name: Peimbert, Manuel
name: Sixtos, Andrés
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: To place meaningful constraints on Big Bang Nucleosynthesis models, the primordial helium abundance determination is crucial. Low-metallicity HII regions have been used to estimate it since their statistical uncertainties are relatively small. We present a new determination of the primordial helium abundance, based on long slit spectra of the HII region NGC 346 in the small Magellanic cloud. We obtained spectra using three $409'' \times 0.51''$ slits divided in 97 subsets. They cover the range $λ\lambda3600-7400$ of the electromagnetic spectrum. We used PyNeb and standard reduction procedures to determine the physical conditions and chemical composition. We found that for NGC 346: $X=0.7465$, $Y=0.2505$ and $Z=0.0030$. By assuming $ΔY / ΔO = 3.3\pm0.7$ we found that the primordial helium abundance is $Y_{\rm P}= 0.2451 \pm 0.0026$ (1$σ$). Our $Y_{\rm P}$ value is in agreement with the value of neutrino families, $N_ν$, and with the neutron half-life time, $τ_{n}$, obtained in the laboratory.
description: Accepted for publication in ApJ. 9 pages, 6 figures, 9 tables
Additional file 1 of Mother-to-infant transmission of the carcinogenic colibactin-producing bacteria
Creators: name: Tsunematsu, Yuta
name: Hosomi, Koji
name: Kunisawa, Jun
name: Sato, Michio
name: Shibuya, Noriko
name: Saito, Emiko
name: Murakami, Haruka
name: Yoshikawa, Yuko
name: Iwashita, Yuji
name: Miyoshi, Noriyuki
name: Mutoh, Michihiro
name: Ishikawa, Hideki
name: Sugimura, Haruhiko
name: Miyachi, Motohiko
name: Wakabayashi, Keiji
name: Watanabe, Kenji
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1.
Extracting the field theory description of a quantum many-body system from experimental data
Creators: name: Zache, Torsten V.
name: Schweigler, Thomas
name: Erne, Sebastian
name: Schmiedmayer, Jörg
name: Berges, Jürgen
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum field theory is a powerful tool to describe the relevant physics governing complex quantum many-body systems. Here we develop a general pathway to extract the irreducible building blocks of quantum field theoretical descriptions and its parameters purely from experimental data. This is accomplished by extracting the one-particle irreducible (1PI) vertices from which one can construct all observables. To match the capabilities of experimental techniques used in quantum simulation experiments, our approach employs a formulation of quantum field theory based on equal-time correlation functions only. We illustrate our procedure by applying it to the quantum sine-Gordon model in thermal equilibrium. The theoretical foundations are illustrated by estimating the irreducible vertices at equal times both analytically and using numerical simulations. We then demonstrate explicitly how to extract these quantities from an experiment where we quantum simulate the sine-Gordon model by two tunnel-coupled superfluids. We extract the full two-point function and the interaction vertex (four-point function) and their variation with momentum, encoding the `running' of the couplings. The measured 1PI vertices are compared to the theoretical estimates, verifying our procedure. Our work opens new ways of addressing fundamental questions in quantum field theory, which are relevant in high-energy and condensed matter physics, and in taking quantum phenomena from fundamental science to practical technology.
description: 18 pages, 11 figures. Updated Phys. Rev. X version with minor changes
Steriphus curvisetosus
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Steriphus
Steriphus curvisetosus

description: Steriphus curvisetosus (Lea, 1928)
 Desiantha curvisetosa Lea, 1928: 376 (type locality: Australia: South Australia, Oodnadatta; type material: S: 2 BMNH).
 Steriphus curvisetosus; Zimmerman, 1994: 698.
 Distribution. Australia (Zimmerman, 1994).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 58, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
The brightest UV-selected galaxies in protoclusters at $z\sim4$: Ancestors of Brightest Cluster Galaxies?
Creators: name: Ito, Kei
name: Kashikawa, Nobunari
name: Toshikawa, Jun
name: Overzier, Roderik
name: Tanaka, Masayuki
name: Kubo, Mariko
name: Shibuya, Takatoshi
name: Ishikawa, Shogo
name: Onoue, Masafusa
name: Uchiyama, Hisakazu
name: Liang, Yongming
name: Higuchi, Ryo
name: Martin, Crystal
name: Lee, Chien-Hsiu
name: Komiyama, Yutaka
name: Huang, Song
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the results of a survey of the brightest UV-selected galaxies in protoclusters. These proto-brightest cluster galaxy (proto-BCG) candidates are drawn from 179 overdense regions of $g$-dropout galaxies at $z\sim4$ from the Hyper Suprime-Cam Subaru Strategic Program identified previously as good protocluster candidates. This study is the first to extend the systematic study of the progenitors of BCGs from $z\sim2$ to $z\sim4$. We carefully remove possible contaminants from foreground galaxies and, for each structure, we select the brightest galaxy that is at least 1 mag brighter than the fifth brightest galaxy. We select 63 proto-BCG candidates and compare their properties with those of galaxies in the field and those of other galaxies in overdense structures. The proto-BCG candidates and their surrounding galaxies have different rest-UV color $(i - z)$ distributions to field galaxies and other galaxies in protoclusters that do not host proto-BCGs. In addition, galaxies surrounding proto-BCGs are brighter than those in protoclusters without proto-BCGs. The image stacking analysis reveals that the average effective radius of proto-BCGs is $\sim28\%$ larger than that of field galaxies. The $i-z$ color differences suggest that proto-BCGs and their surrounding galaxies are dustier than other galaxies at $z\sim4$. These results suggest that specific environmental effects or assembly biasses have already emerged in some protoclusters as early as $z \sim 4$, and we suggest that proto-BCGs have different star formation histories than other galaxies in the same epoch.
description: 18 pages, 11 figures, Accepted for publication in ApJ
Risks of adverse perinatal and maternal outcomes among women with hypertensive disorders of pregnancy in southwestern Uganda
Creators: name: Lugobe, Henry Mark
name: Muhindo, Rose
name: Kayondo, Musa
name: Wilkinson, Ian
name: Agaba, David Collins
name: McEniery, Carmel
name: Okello, Samson
name: Wylie, Blair J.
name: Boatin, Adeline A.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: subject: Research Article
subject: Medicine and health sciences
subject: Physical sciences
subject: FOS: Physical sciences

description: Introduction: Hypertensive disorders of pregnancy (HDP) are a leading cause of global perinatal (fetal and neonatal) and maternal morbidity and mortality. We sought to describe HDP and determine the magnitude and risk factors for adverse perinatal and maternal outcomes among women with HDP in southwestern Uganda. Methods: We prospectively enrolled pregnant women admitted for delivery and diagnosed with HDP at a tertiary referral hospital in southwestern Uganda from January 2019 to November 2019, excluding women with pre-existing hypertension. The participants were observed and adverse perinatal and maternal outcomes were documented. We used multivariable logistic regression models to determine independent risk factors associated with adverse perinatal and maternal outcomes. Results: A total of 103 pregnant women with a new-onset HDP were enrolled. Almost all women, 93.2% (n = 96) had either pre-eclampsia with severe features or eclampsia. The majority, 58% (n = 60) of the participants had an adverse perinatal outcome (36.9% admitted to the neonatal intensive care unit (ICU), 20.3% stillbirths, and 1.1% neonatal deaths). Fewer participants, 19.4% (n = 20) had an adverse maternal outcome HELLP syndrome (7.8%), ICU admission (3%), and postpartum hemorrhage (3%). In adjusted analyses, gestational age of < 34 weeks at delivery and birth weight <2.5kg were independent risk factors for adverse perinatal outcomes while referral from another health facility and eclampsia were independent risk factors for adverse maternal outcomes. Conclusion: Among women with HDP at our institution, majority had preeclampsia with severe symptoms or eclampsia and an unacceptably high rate of adverse perinatal and maternal outcomes; over a fifth of the mothers experiencing stillbirth. This calls for improved antenatal surveillance of women with HDP and in particular improved neonatal and maternal critical care expertise at delivering facilities. Earlier detection and referral, as well as improvement in initial management at lower level health units and on arrival at the referral site is imperative.
The Atick-Witten free energy, closed tachyon condensation and deformed Poincare' symmetry
Creators: name: Maggiore, Michele
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The dependence of the free energy of string theory on the temperature at T much larger than the Hagedorn temperature was found long ago by Atick and Witten and is $F(T)\sim ΛT^2$, where $Λ$ diverges because of a tachyonic instability. We show that this result can be understood assuming that, above the Hagedorn transition, Poincare' symmetry is deformed into a quantum algebra. Physically this quantum algebra describes a non-commutative spatial geometry and a discrete euclidean time. We then show that in string theory this deformed Poincare' symmetry indeed emerges above the Hagedorn temperature from the condensation of vortices on the world-sheet. This result indicates that the endpoint of the condensation of closed string tachyons with non-zero winding is an infinite stack of spacelike branes with a given non-commutative world-volume geometry. On a more technical side, we also point out that $T$-duality along a circle with antiperiodic boundary conditions for spacetime fermions is broken by world-sheet vortices, and the would-be T-dual variable becomes non-compact.
description: 31 pages, 3 figures
Calibration Unit Design for High Resolution Infrared Spectrograph for Exoplanet Characterization (HISPEC)
Creators: name: Sappey, Ben
name: Konopacky, Quinn
name: Jovanovic, Nemanja
name: Baker, Ashley
name: Maire, Jerome
name: Halverson, Samuel
name: Mawet, Dimitri
name: Ruffio, Jean-Baptiste
name: Bertz, Rob
name: Fitzgerald, Michael
name: Beichman, Charles
name: Ruane, Garreth
name: Kassis, Marc
name: Johnson, Chris
name: Magnone, Ken
Publisher: name: Proceedings of AO4ELT7 conference 2023 - Editors: Thierry Fusco and Benoit Neichel
Year: 2023
Subjects: HIGH
RESOLUTION SPECTROSCOPY
ASTRONOMICAL INSTRUMENTATION
CALIBRATION
PRECISION RADIAL VELOCITY

description: The latest generation of high-resolution spectrograph instruments on 10m-class telescopes continues to pursue challenging science cases. Consequently, evermore precise calibration methods are necessary to enable trail-blazing science methodology. We present the High-resolution Infrared SPectrograph for Exoplanet Characterization (HISPEC) Calibration Unit (CAL), designed to enable challenging science cases such as Doppler imaging of exoplanet atmospheres, precision radial velocity, and high-contrast high-resolution spectroscopy of nearby exoplanets. CAL builds upon the heritage from the pathfinder instrument Keck Planet Imager and Characterizer (KPIC) (Mawet et al. 2016, Delorme et al. 2018, Delorme et al. 2021), and utilizes four near-infrared (NIR) light sources encoded with wavelength information that are coupled into single-mode fiber. They can be used synchronously during science observations or asynchronously during daytime calibrations. A hollow cathode lamp (HCL) and a series of gas absorption cells provide absolute calibration from 0.98Im to 2.4Im. A laser frequency comb (LFC) provides stable, time-independent wavelength information during observation and CAL implements a lower finesse astro-etalon as a backup for the LFC. Design lessons from instrumentation like HISPEC will serve to inform the requirements for similar instruments for the ELTs in the future.
Steriphus incotaminatus
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Steriphus
Steriphus incotaminatus

description: Steriphus incotaminatus (Lea, 1899)
 Desiantha incontaminata Lea, 1899: 141 (type locality: Australia: New South Wales, Burrawang; type material: H: BMNH).
 Steriphus incontaminatus; Zimmerman, 1994: 698.
 Distribution. Australia (Zimmerman, 1994).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 58, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Additional file 1 of Universal minicircle sequence binding protein of Leishmania donovani regulates pathogenicity by controlling expression of cytochrome-b
Creators: name: Singh, Ruby
name: Purkait, Bidyut
name: Abhishek, Kumar
name: Saini, Savita
name: Das, Sushmita
name: Verma, Sudha
name: Mandal, Abhishek
name: Ghosh, Ayan Kr.
name: Ansari, Yousuf
name: Kumar, Ashish
name: Sardar, Abul H.
name: Kumar, Ajay
name: Parrack, Pradeep
name: Das, Pradeep
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Computational Biology

description: Additional file 1: Figure S1. 3D Model of LdUMSBP designed by Bio-informatics tools. Figure S2. Expression, Purification of recombinant LdUMSBP and Generation of anti-LdUMSBP Antibody. Figure S3. Immunolocalization of LdUMSBP in kDNA disk demonstrated by Phase and Fluorescence Microscopy. Figure S4. Redox potential controls oxidation-reduction status of UMSBP and its binding activity. Figure S5. PCR amplification of HYG and NEO gene from LdU−/− parasites, confirming the successful deletion of two allele of UMSBP by the Hygromycin and Neomycin cassette. Figure S6. Southern blot to demonstrate the deletion of two alleles of LdUMSBP from L. donovani genome. Figure S7. Phase contrast microphotograph after Geimsa staining of infected macrophages [infected with wild type (R), single knock out LdUMSBP (LdU−/+) and double knock out LdUMSBP (LdU−/−). Table S1. List of Primers. Table S2. Interacting amino acids of LdUMSBP with UMS sequence in docking study.
Steriphus inermis
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Steriphus
Steriphus inermis

description: Steriphus inermis (Lea, 1928)
 Desiantha inermis Lea, 1928: 377 (type locality: Australia: North Western Australia, Derby; type material: H: BMNH).
 Steriphus inermis; Zimmerman, 1994: 698.
 Distribution. Australia (Zimmerman, 1994).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 58, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
An investig-ation into the epidemiology of chikungunya virus across neglected regions of Indonesia
Creators: name: Stubbs, Samuel C. B.
name: Johar, Edison
name: Yudhaputri, Frilasita A.
name: Yohan, Benediktus
name: Santoso, Marsha S.
name: Hayati, Rahma F.
name: Denis, Dionisius
name: Blacklaws, Barbara A.
name: Powers, Ann M.
name: Sasmono, R. Tedjo
name: Myint, Khin Saw Aye
name: Frost, Simon D. W.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: subject: Research Article
subject: Biology and life sciences
subject: Medicine and health sciences
subject: People and places
subject: Research and analysis methods
subject: Computer and information sciences
subject: FOS: Computer and information sciences

description: Funder: US-CDC
description: Background: Chikungunya virus (CHIKV) is an important emerging and re-emerging public health problem worldwide. In Indonesia, where the virus is endemic, epidemiological information from outside of the main islands of Java and Bali is limited. Methodology/Principal Findings: Four hundred and seventy nine acutely febrile patients presenting between September 2017–2019 were recruited from three city hospitals situated in Ambon, Maluku; Banjarmasin, Kalimantan; and Batam, Batam Island as part of a multi-site observational study. CHIKV RNA was detected in a single serum sample while a separate sample was IgM positive. IgG seroprevalence was also low across all three sites, ranging from 1.4–3.2%. The single RT-PCR positive sample from this study and 24 archived samples collected during other recent outbreaks throughout Indonesia were subjected to complete coding region sequencing to assess the genetic diversity of Indonesian strains. Phylogenetic analysis revealed all to be of a single clade, which was distinct from CHIKV strains recently reported from neighbouring regions including the Philippines and the Pacific Islands. Conclusions/Significance: Chikungunya virus strains from recent outbreaks across Indonesia all belong to a single clade. However, low-level seroprevalence and molecular detection of CHIKV across the three study sites appears to contrast with the generally high seroprevalences that have been reported for non-outbreak settings in Java and Bali, and may account for the relative lack of CHIKV epidemiological data from other regions of Indonesia.
title: Charge change-induced beam losses under dynamic vacuum conditions in ring accelerators
Creators: name: Omet, C.
name: Spiller, P.
name: Stadlmann, J.
name: Hoffmann, D. H. H.
Publisher: name: IOP Publishing
Year: 2024

description: Intense heavy ion beams from the Gesellschaft für Schwerionenforschung (GSI-Darmstadt) accelerator facilities are investigated for their potential to drive inertial fusion targets and are currently used to generate and probe high-energy-density (HED) matter. The existing heavy ion synchrotron facility SIS-18 delivers intense uranium beam pulses for experiments with up to 4× 10⁹ ions per bunch at a charge state of q = 73+. Higher intensities are potentially available at lower charge states, when related loss mechanisms can be overcome. We have observed intensity-dependent beam losses in SIS-18. The origin of these beam losses is attributed to processes changing the charge state of ions, which is predominantly due to collisions with rest gas atoms. The resulting change in the mass over charge ratio m/q leads to modified trajectories in dispersive beam transport elements, and finally to the loss of the particle at the vacuum tube wall. At the impact position secondary particles are produced by ion-induced desorption and as a result the pressure in the vacuum tube is increased locally. This local rise in pressure in turn leads to increased charge changing processes starting an avalanche process that may eventually lead to a complete loss of the beam during a few turns in the synchrotron. In this paper, we discuss a method to control the problem of desorbed gases with specifically designed beam catchers at critical positions. We have further developed a program package to calculate the most important beam loss mechanisms and to couple them to the dynamic vacuum problem. The basis of this simulation is an ion–optics routine where relevant atomic processes and the effects of dynamic vacuum are implemented.
Thymically-derived Foxp3+ regulatory T cells are the primary regulators of type 1 diabetes in the non-obese diabetic mouse model
Creators: name: Holohan, Daniel
name: Gool, Frédéric Van
name: Bluestone, Jeffrey A.
Publisher: name: figshare
Year: 2019
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: This project folder includes all data for experiments published in the PLOS One article titled "Thymically-derived Foxp3+ regulatory T cells are the primary regulators of type 1 diabetes in the non-obese diabetic mouse model"
All numerical values used to make figures are found one Excel file with multiple sheets for each graph made. All original flow cytometry files are also attached, with each experiment organized into a folder containing a Word document with the corresponding staining panel. Lastly, a PowerPoint file including the original gel image used to identify the CNS1-deletion founder mouse is included.
The only files not included directly in this project folder are the pancreata histology images used for insulitis scoring. The original high-resolution images are publicly accessible at the following link: https://app.histowiz.com/shared_orders/a3ff1bf4-fe4c-4b57-87aa-badff26d53ae/slides/
Rupanius carinatus Morrone 1995
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Rupanius
Rupanius carinatus

description: Rupanius carinatus Morrone, 1995
 Rupanius carinatus Morrone, 1995c: 604 (type locality: Colombia: Cauca, 20 km E Silvia; type material: H: CNCI and P: 1 CNCI).
 Distribution. Colombia (Morrone, 1995c).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 56, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Enhanced biofilm and extracellular matrix production by chronic carriage versus acute isolates of Salmonella Typhi
Creators: name: Devaraj, Aishwarya
name: González, Juan F.
name: Eichar, Bradley
name: Thilliez, Gatan
name: Kingsley, Robert A.
name: Baker, Stephen
name: Allard, Marc W.
name: Bakaletz, Lauren O.
name: Gunn, John S.
name: Goodman, Steven D.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: subject: Research Article
subject: Biology and life sciences
subject: Medicine and health sciences
subject: Computer and information sciences
subject: FOS: Computer and information sciences

description: Salmonella Typhi is the primary causative agent of typhoid fever; an acute systemic infection that leads to chronic carriage in 3–5% of individuals. Chronic carriers are asymptomatic, difficult to treat and serve as reservoirs for typhoid outbreaks. Understanding the factors that contribute to chronic carriage is key to development of novel therapies to effectively resolve typhoid fever. Herein, although we observed no distinct clustering of chronic carriage isolates via phylogenetic analysis, we demonstrated that chronic isolates were phenotypically distinct from acute infection isolates. Chronic carriage isolates formed significantly thicker biofilms with greater biomass that correlated with significantly higher relative levels of extracellular DNA (eDNA) and DNABII proteins than biofilms formed by acute infection isolates. Importantly, extracellular DNABII proteins include integration host factor (IHF) and histone-like protein (HU) that are critical to the structural integrity of bacterial biofilms. In this study, we demonstrated that the biofilm formed by a chronic carriage isolate in vitro, was susceptible to disruption by a specific antibody against DNABII proteins, a successful first step in the development of a therapeutic to resolve chronic carriage.
Universal scaling of the velocity field in crack front propagation
Creators: name: Priol, Clément Le
name: Chopin, Julien
name: Doussal, Pierre Le
name: Ponson, Laurent
name: Rosso, Alberto
Publisher: name: arXiv
Year: 2019
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The propagation of a crack front in disordered materials is jerky and characterized by bursts of activity, called avalanches. These phenomena are the manifestation of an out-of-equilibrium phase transition originated by the disorder. As a result avalanches display universal scalings which are however difficult to characterize in experiments at finite drive. Here we show that the correlation functions of the velocity field along the front allow to extract the critical exponents of the transition and to identify the universality class of the system. We employ these correlations to characterize the universal behavior of the transition in simulations and in an experiment of crack propagation. This analysis is robust, efficient and can be extended to all systems displaying avalanche dynamics.
description: 5 pages + 6 pages SupMat, 5+4 figures
Wulff-Based Approach to Modeling the Plasmonic Response of Single Crystal, Twinned, and Core-Shell Nanoparticles.
Creators: name: Boukouvala, Christina
name: Ringe, Emilie
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019

description: The growing interest in plasmonic nanoparticles and their increasingly diverse applications is fuelled by the ability to tune properties via shape control, promoting intense experimental and theoretical research. Such shapes are dominated by geometries that can be described by the kinetic Wulff construction such as octahedra, thin triangular platelets, bipyramids, and decahedra, to name a few. Shape is critical in dictating the optical properties of these nanoparticles, in particular their localized surface plasmon resonance behavior, which can be modeled numerically. One challenge of the various available computational techniques is the representation of the nanoparticle shape. Specifically, in the discrete dipole approximation, a particle is represented by discretizing space via an array of uniformly distributed points-dipoles; this can be difficult to construct for complex shapes including those with multiple crystallographic facets, twins, and core-shell particles. Here, we describe a standalone user-friendly graphical user interface (GUI) that uses both kinetic and thermodynamic Wulff constructions to generate a dipole array for complex shapes, as well as the necessary input files for DDSCAT-based numerical approaches. Examples of the use of this GUI are described through three case studies spanning different shapes, compositions, and shell thicknesses. Key advances offered by this approach, in addition to simplicity, are the ability to create crystallographically correct structures and the addition of a conformal shell on complex shapes.