cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identification of phosphorylation sites of TOPORS and a role for phosphorylated residues in the regulation of ubiquitin and SUMO E3 ligase activity
Creators: name: Park, Hye-Jin
Publisher: name: No Publisher Supplied
Year: 2008

description: TOPORS is the first example of a protein that possesses both ubiquitin and SUMO E3 ligase activity. The ubiquitination activity maps to a conserved RING domain in the N-terminal region of the protein, which is not required for sumoylation activity. Similar to other E3 ligases, it is likely that the ubiquitin and sumoylation activities of TOPORS are regulated by post-translational modifications. Therefore, we employed mass spectrometry to identify post-translational modifications of TOPORS. Several putative phosphorylated regions were identified in conserved regions of the protein. We investigated the role of phosphorylation of serine 98, which is adjacent to the RING domain, in both cells and in vitro. Mutation of serine 98 to aspartic acid resulted in an increase in the ubiquitin ligase activity of TOPORS both in cells and in vitro. In addition, this mutation increased the binding of TOPORS to the E2 enzyme UbcH5a. Conversely, a phospho-deficient mutant (S98A) exhibited little change in ubiquitin ligase activity compared to wild-type TOPORS, both in cells and in vitro. Neither of the mutants affected the localization of TOPORS to punctate nuclear regions. In addition, neither mutant affected the SUMO ligase activity of TOPORS in cells or in vitro. Our findings indicate that phosphorylation of serine 98 regulates the ubiquitin but not the SUMO ligase activity of TOPORS, consistent with a potential binary switch function for TOPORS in protein ubiquitination versus sumoylation.
Vitamin D-mediated suppression of mammary tumorigenesis and mechanism of action
Creators: name: Lee, Hong Jin
Publisher: name: No Publisher Supplied
Year: 2008

description: Numerous preclinical, epidemiological and clinical studies with vitamin D and analogs have suggested the benefits of vitamin D and analogs for prevention and treatment of cancer. However, the hypercalcemic effects have limited the use of  1alpha,25(OH)2D3, the hormonally active form of vitamin D. Gemini vitamin D analogs with a unique structure of two six-carbon chains have shown activity in inhibiting tumor growth of colon cancer cells without inducing hypercalcemia. However, the molecular mechanism of Gemini vitamin D analogs has not been studied. Here, we have investigated the effects of novel Gemini vitamin D analogs on suppressing mammary tumorigenesis and the mechanism of action in breast cancer in vitro and in vivo. We found that Gemini vitamin D analogs exhibited better inhibition of cell growth than 1alpha,25(OH)2D3 and regulated the cell proliferating related markers including the cyclin dependent kinase inhibitor, p21 and insulin-like growth factor binding protein 3 (IGFBP-3) in MCF10AT1 human breast epithelial cells. The transforming growth factor beta (TGF-beta) superfamily has been suggested to cross-talk with vitamin D signaling, and we determined that Gemini vitamin D analog Ro3582 activated Smads (Smad1/5), down-stream mediators of bone morphogenetic protein (BMP) signaling. In the study of upstream signaling pathways, we found that Ras/PKC alpha was involved in Smad activation and cell growth inhibition by Ro3582, suggesting that the Ras/PKC alpha-Smad signaling pathway may mediate the inhibition of cell proliferation by Gemini vitamin D analog Ro3582 in MCF10 human breast epithelial cells. Gemini vitamin D analogs exerted significant in vivo suppression of mammary tumorigenesis without inducing hypercalcemic toxicity in three different animal models: 1) N-methyl-N-nitrosourea (NMU)-induced estrogen receptor (ER) positive breast cancer, 2) ER-negative MCF10DCIS xenografts, and 3) an MMTV-her2/neu transgenic mouse model. These results suggest that Gemini vitamin D analogs be used as potent agents in the prevention and/or inhibition of different subtypes of breast cancers including luminal, Her2 positive and basal-like breast cancer. In conclusion, Gemini vitamin D analogs regulate Smad signaling via the Ras/PKC alpha pathway, and may be potent agents for the prevention and treatment of breast cancer without calcemic toxicity.
Gabrius sterna Hromadka 2014
Creators: name: Mikátová, Šárka
name: Macháčková, Lenka
name: Hájek, Jiří
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Gabrius
Gabrius sterna

description: Gabrius sterna Hromádka, 2014
Gabrius sterna Hromádka, 2014h: 188, Figs 51–53.
The holotype is deposited in NMPC (general collection):
HƟĿƟ*´YPൾ (): ‘ [p, green label] // MALAWI S Jall env. / 30 km SE of Zamba / 26.-27.xii.2001 / J. Bezděk lgt. [p] // ex coll. L. Hromádka / National Museum / Prague, Czech Republic [p] // HOLOTYPUS / GABRIUS Stephens / sterna sp. nov. / Hromádka, det., 2014. [p, yellow label]’.
Current status. Valid species.
description: Published as part of Mikátová, Šárka, Macháčková, Lenka & Hájek, Jiří, 2020, Catalogue of type specimens of beetles (Coleoptera) deposited in the National Museum, Prague, Czech Republic, pp. 353-389 in Acta Entomologica Musei Nationalis Pragae 60 (1) on page 361, DOI: 10.37520/aemnp.2020.021, http://zenodo.org/record/3880030
Idiostiba venezuelensis Pace 2009, n. sp.
Creators: name: Pace, Roberto
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Idiostiba
Idiostiba venezuelensis

description: Idiostiba venezuelensis n. sp.
(Figg. 97-99)
Materiale tipico: Holotypus , Venezuela, Colonia Tovar, b. Maracay, 2000 m, leg. H. Franz (MHMW).
Descrizione:
Lunghezza 3,3 mm. Corpo lucidissimo e bruno-rossiccio, con capo nero, pronoto e uroterghi liberi terzo, quarto e quinto bruni; antenne brune con i due antennomeri basali giallo-rossicci; zampe giallo-rossicce. Punteggiatura del capo fine, evidente e rada, quella delle elitre meno fine, altrettanto evidente. Granulosità del pronoto ben visibile. Reticolazione dell’avancorpo assente, quella dell’addome molto trasversa e molto superficiale. Edeago figg. 98-99.
Comparazioni:
L’habitus della nuova specie è simile a quello di I. missionum (BERNHAUER, 1934) comb. n., dell’Argentina («olim» Atheta (Microdota) missionum BERNHAUER, 1934: 503) (holotypus  da me esaminato). Se ne distingue per avere il quarto antennomero lungo quanto largo (fortemente trasverso e minuscolo rispetto al seguente in missionum) e per la pubescenza dell’addome poco fitta e non fittissima come in missionum.
Etimologia: La nuova specie prende nome dal Venezuela.
description: Published as part of Pace, Roberto, 2009, Nuovi dati faunistici e tassonomici su Aleocharinae delle tribù Lomechusini, Hoplandriini, Oxypodini e Aleocharini del Sudamerica (Coleoptera, Staphylinidae), pp. 133-173 in Beiträge Zur Entomologie = Contributions to Entomology 59 (1) on pages 161-164, DOI: 10.21248/contrib.entomol.59.1.133-173, http://zenodo.org/record/4752253
Gabrius sternula Hromadka 2014
Creators: name: Mikátová, Šárka
name: Macháčková, Lenka
name: Hájek, Jiří
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Gabrius
Gabrius sternula

description: Gabrius sternula Hromádka, 2014
Gabrius sternula Hromádka, 2014i: 204, Figs 31–33.
One paratype is deposited in NMPC (ex coll. L. Hromádka):
PA*©A*´YPൾ) (: ‘ TANZANIA 2224m / Mount Meru, Arusha N.P. / S03º14ʹ54ʺ;E36º48ʹ21ʺ / 2-4.iv.12 Dung Pitfall / leg. Smith,R & Takano,H [p] // BMNH{E} / 2012-92 / 1233175 [p] // ex coll. L. Hromádka / National Museum / Prague, Czech Republic [p] // PA- RATYPUS / GABRIUS Stephens / sternula sp. nov. / Hromádka, det., 2014. [p, red label]’.
Current status. Valid species.
description: Published as part of Mikátová, Šárka, Macháčková, Lenka & Hájek, Jiří, 2020, Catalogue of type specimens of beetles (Coleoptera) deposited in the National Museum, Prague, Czech Republic, pp. 353-389 in Acta Entomologica Musei Nationalis Pragae 60 (1) on page 361, DOI: 10.37520/aemnp.2020.021, http://zenodo.org/record/3880030
Gabrius streptopelia Hromadka 2014
Creators: name: Mikátová, Šárka
name: Macháčková, Lenka
name: Hájek, Jiří
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Gabrius
Gabrius streptopelia

description: Gabrius streptopelia Hromádka, 2014
Gabrius streptopelia Hromádka, 2014h: 189, Figs 54–56.
The holotype and one paratype are deposited in NMPC
(general collection and ex coll. L. Hromádka):
HƟĿƟ*´YPൾ (): ‘ Liberia:/ Charlesville [p] / 14.VI.1962 [hw] // Ex debris / Nest No [p] … [hw, illegible] // ex coll. L. Hromádka / National Museum / Prague, Czech Republic [p] // HOLOTYPUS / GAB- RIUS Stephens / streptopelia spec. nov. / Hromádka, det., 2012. [p, yellow label]’.
PA*©A*´YPൾ) (: ‘ LIBERIA / Mt. Nimba / Grassfield / 16.-25.ix. 1979 [p] // ex coll. L. Hromádka / National Museum / Prague, Czech Republic [p] // PARATYPUS / GABRIUS Stephens / streptopelia sp. nov / Hromádka det., 2013. [p, yellow label]’.
Current status. Valid species.
description: Published as part of Mikátová, Šárka, Macháčková, Lenka & Hájek, Jiří, 2020, Catalogue of type specimens of beetles (Coleoptera) deposited in the National Museum, Prague, Czech Republic, pp. 353-389 in Acta Entomologica Musei Nationalis Pragae 60 (1) on page 361, DOI: 10.37520/aemnp.2020.021, http://zenodo.org/record/3880030
Influence of increasing surface humidity on winter warming at high altitudes through the 21st century
Creators: name: Rangwala, Imtiaz
Publisher: name: No Publisher Supplied
Year: 2008

description: This dissertation examines the influence of low-level atmospheric humidity in mediating the rate of surface warming, particularly at high altitude regions, during the late 20th century and the 21st century. The focus is on observations and global climate model projections (IPCC SRES A1B scenario) for China, the Tibetan Plateau (TP) and the San Juan Mountain (SJM) in southwest Colorado.  For China, the analysis suggests large surface warming despite significant decreases in insolation until the middle of the 21st century. Both the past and future warming in China occurs primarily as a result of the lower and upper atmospheric water vapor feedbacks, triggered by the increase in anthropogenic greenhouse gases, which in turn causes an increase in downward longwave radiation (DLR). For the TP and the SJM region, I find that increases in surface specific humidity (q) leads to relatively large increases in DLR.  This effect is enhanced in colder months and at higher altitudes, and the winter warming in the TP is about twice the warming during other seasons. For the TP, the model shows that for the highest elevations the largest warming between 1950-2100 occurs during winter and spring. The increases in DLR influenced by increases in q during winter, and increases in absorbed solar radiation influenced by decreases in snow cover extent during spring are, in part, the reason for a large warming trend over the plateau. These two effects appear to produce the model’s elevation dependent warming trend. For the SJM region, the observations show that q has been increasing at more than 10% per decade from October through January between 1990-2005, when the region experienced the largest increases in surface temperatures. Moreover, only during these months do diurnal changes in humidity explain the large variability in the corresponding changes in temperature. The largest changes in DLR also appear to occur during these months. Large increases in DLR during January and December coincide with large increases in temperatures and, in part, indicate the causes for a large warming trend during these months.
Perceptual decisions under risk in a motion extrapolation paradigm
Creators: name: Shah, Shalin
Publisher: name: No Publisher Supplied
Year: 2008

description: Classical work on decision-making has demonstrated systematic deviations from normative behavior. Recent experiments on movement planning, however, have shown that subjects can be indistinguishable from optimality in their visuo-motor decisions (Trommershaeuser et al., 2003a, 2003b). Unlike the classical case, the uncertainty in the visuo-motor case is internal to the subjects; it arises from their motor variability—variability in executing a motor action.   We asked whether observers can also combine the intrinsic variability in their perceptual representation with externally-specified reward-and-penalty structure to make optimal decisions. We extended a paradigm used to study the visual extrapolation of static contour geometry (Singh & Fulvio, 2005), to examine observers’ decisions under risk in extrapolating curved motion trajectories. Observers viewed a dot moving along a parabolic trajectory disappear behind the straight-edge of a half-disk occluder. Their task was to “catch” the dot from the opposite curved side, by adjusting the angular position of an arc or “mitt”. In the risky conditions, a double-mitt was used, comprising a green reward region and a red penalty region, with partial overlap. Observers’ gains/losses were determined by the part of the double-mitt that “caught” the dot. Variables manipulated were: trajectory curvature, penalty value, and mitt overlap. Observers’ performance in the baseline condition was used to estimate individual bias and variability. Based on these, predictions of optimal shift and optimal score were computed, using maximization of expected gain. We found that observed shifts were well predicted by optimal shifts. Moreover, observer efficiency (observed/optimal score) was high (80% - 114%). The results indicate that observers are implicitly aware of the instrinsic variability in their perceptual representation, and can combine it with externally-specified reward-and-penalty structure to make near- optimal decisions.
Gabrius taphozous Hromadka 2011
Creators: name: Mikátová, Šárka
name: Macháčková, Lenka
name: Hájek, Jiří
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Gabrius
Gabrius taphozous

description: Gabrius taphozous Hromádka, 2011
Gabrius taphozous Hromádka, 2011f: 1391, Figs 40–42.
One paratype is deposited in NMPC (ex coll. L. Hromádka):
PA*©A*´YPൾ (): ‘ Madagascar Nord / 600-700 m / Massiv Anjanaharibe Nord / sentier Ambodihasina- / Ambalarombe [p] // Riv.Andramonta env./ 24-29.2.96 / forêt humide, marais / J.Janák + P.Moravec lgt. [p] // ex coll. L. Hromádka / National Museum / Prague, Czech Republic [p] // PARATYPUS / GABRIUS Stephens / taphozous sp. nov. / Hromádka, det. 2007 [p, orange label]’.
Current status. Valid species.
description: Published as part of Mikátová, Šárka, Macháčková, Lenka & Hájek, Jiří, 2020, Catalogue of type specimens of beetles (Coleoptera) deposited in the National Museum, Prague, Czech Republic, pp. 353-389 in Acta Entomologica Musei Nationalis Pragae 60 (1) on page 361, DOI: 10.37520/aemnp.2020.021, http://zenodo.org/record/3880030
title: Measurement of neural functionality using phase sensitive optical coherence reflectometry
Creators: name: Milner, Thomas E.
name: Dave, Digant P.
name: Akkin, Taner
name: Rylander, H. Grady
Publisher: name: United States Patent and Trademark Office
Year: 2016
Subjects: subject: A61B5/4041
subject: A61B5/0066
subject: A61B5/0075
subject: A61B5/0082
subject: A61B5/40
subject: A61B5/4029
subject: A61B5/6821
subject: A61B5/7225
subject: A61B5/7282
subject: A61N1/00
subject: A61N1/3605
subject: A61N5/0622
subject: No longer published

description: Optical methods, devices, and systems for noninvasively detecting transient surface displacements in a neuron are disclosed. Methods, devices, and systems provided may employ a phase-sensitive optical low coherence reflectometer. In addition, surface displacements due to action potential propagation in neural tissues may be detected in some embodiments using back-reflected light. According to some embodiments, exogenous chemicals or reflect ion coatings are not required. Transient neural surface displacement of less then 1 nm in amplitude and 1 ms in duration may be detected and may be generally coincident with action potential arrival to the optical measurement site. The systems and methods may be used for noninvasive detection of various neuropathies such as retinal neuropathies. They may also be useful in detecting the effects of various pharmacological agents.
Development of anti-inflammatory agents from the aromatic plants, Origanum spp. and Mentha spp., and analytical methods on the quality control of bioactive phenolic compounds
Creators: name: Shen, Diandian
Publisher: name: No Publisher Supplied
Year: 2008

description: The development of new anti-inflammatory drugs comes at high cost and risk, as evidenced by the fact that several novel prescription non-steroidal anti-inflammatory drugs (NSAIDs) have been withdrawn from the market due to potential health risks. Meanwhile, natural dietary supplements with anti-inflammatory activities are gaining increased interest by consumers and industry as they are perceived to be of lower cost, with fewer adverse effects and yet function as complementary and alternative medicines. We successfully identified the anti-inflammatory constituents from post-distillationmaterial of oregano, an aromatic plant long prized as a food seasoning and spice in western and Middle Eastern cuisine and a rich source of essential oil. The anti-inflammatory compounds in oregano were identified as rosmarinic acid, oleanolic acid and ursolic acid by using bioactivity-guided isolation, LC/MS and NMR techniques. We subsequently elucidated their possible inhibitory mechanisms during the inflammatory cell signaling pathways by screening different bioassays, and a synergistic action for the combination of these three compounds was observed on the LPS-induced nitrite production assay. An LC/MS (SIM mode) method employing a tandem column system was developed for the simultaneous quantitation of these three compounds in oregano. Validation for this method showed a precision (relative standard deviation) ranging from 4.84% to 6.41%, and the recoveries varied from 92.2% to 100.8% for the three analytes. In order to investigate genetic diversity between species and within a species relative to the anti-inflammatory compounds, different oregano species, varieties and breeding lines were collected from around the world, vegetatively field transplanted into a Rutgers Agricultural Research Experiment Station farm, where the plants were field grown, harvested and quantitated for their anti-inflammatory contents based upon the LC/MS method developed in this study. We next examed mint, another aromatic plant in the Lamiaceae family, and proved that these three anti-inflammatory compounds also accumulated in this plant. An analytical survey was further performed to determine anti-inflammatory agent-rich sources from eight commercial mint species as well as many specialty varieties within the different species. To facilitate the frequent quality control requirement and material pre-evaluation, we developed and validated a near-infrared spectroscopy (NIR) method for the fast quantitation of anti-inflammatory constituents in oregano and mint. Finally, we investigated the anti-inflammatory compound distribution and related chemical properties of the oregano post-distillation materials.
Diacanthochara brasiliensis Pace 2009, n. sp.
Creators: name: Pace, Roberto
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Diacanthochara
Diacanthochara brasiliensis

description: Diacanthochara brasiliensis n. sp.
(Figg. 100-103)
Materiale tipico: Holotypus , Brasilien, Nova Teutonia, VI.1960, 300- 500 m, leg. Plaumann (MB).
Paratypi: 3 , stessa provenienza (MB), (MRSNT).
Descrizione:
Lunghezza 2,8 mm. Corpo lucidissimo e rossiccio con elitre bruno-rossicce; antenne brune con i tre antennomeri basali giallo-rossicci; zampe rossicce. Punteggiatura del capo e del pronoto superficiale, quella delle elitre e dell’addome evidente. Reticolazione del corpo assente, tranne che sulle elitre su cui è superficiale. Quattro punti forti discali sul pronoto. Primo urotergo libero del maschio con due prolungamenti laterali e un lobo mediano al margine posteriore. Edeago figg. 101-102, spermateca fig. 103.
Comparazioni:
La nuova specie è simile a D. venezuelana PACE, 1983, del Venezuela, per la forma dell’edeago, ma questo nella nuova specie è molto dilatato nella porzione apicale distale, in visione ventrale, mentre è stretto in venezuelana. Il quarto antennomero, inoltre, è lungo quanto largo nella nuova specie, trasverso in venezuelana. La spermateca è semplice nella nuova specie e avvolta in numerose spire in venezuelana.
Etimologia: La nuova specie prende nome dal Brasile.
description: Published as part of Pace, Roberto, 2009, Nuovi dati faunistici e tassonomici su Aleocharinae delle tribù Lomechusini, Hoplandriini, Oxypodini e Aleocharini del Sudamerica (Coleoptera, Staphylinidae), pp. 133-173 in Beiträge Zur Entomologie = Contributions to Entomology 59 (1) on page 164, DOI: 10.21248/contrib.entomol.59.1.133-173, http://zenodo.org/record/4752253
Circadian regulation of innate immunity and microRNAs in Drosophila melanogaster
Creators: name: Lee, Jung-Eun
Publisher: name: No Publisher Supplied
Year: 2008

description: The main parts of my thesis are studies aimed at investigating circadian regulation of innate immunity using Drosophila as a model system.  In unrelated work, I also participated in a collaborative study showing circadian regulation of microRNAs (miRNAs) in Drosophila.We sought to determine if the innate immune response is under circadian regulation and whether this impacts overall health status.  To this end, Drosophila was infected with the human opportunistic pathogenic bacteria Pseudomonas aeruginosa as a model system.  The results show that the survival rates of wild-type flies vary as a function of when during the day they are infected, peaking in the middle of the night.  Also the kinetics of bacterial growth and the expression of a limited number of innate immunity genes correlate with time-of-day effects on survival.  Our findings suggest that medical intervention strategies incorporating chronobiological considerations could enhance the innate immune response, boosting the efficacy of combating pathogenic infections.  This study also led us to a second study where we characterized the innate immune response in the Drosophila head.  We showed that the innate immunity pathway in the head is similar to the well described pathway in the body.  Furthermore, the pericerebral fat body in the head or neurons are sufficient to combat bacterial infections, independent of the abdominal fat body.  Our findings suggest that the pericerebral fat body may provide a fast and local immune response in the head, improving the survival outcome of Drosophila.A minor aspect of my thesis work was unrelated to host defense.  In this study, we used Drosophila to investigate the possibility that circadian clocks regulate the expression of miRNAs.  From the analysis of microarray data, we found two miRNAs (dme-miR-263a and -263b) that exhibit robust daily changes in abundance in adult heads of wild-type flies that are abolished in the cyc01 mutant.  Our results suggest that cycling miRNAs contribute to daily changes in mRNA and/or protein levels in Drosophila.
Additional file 2: of The efficacy and stability of an information and communication technology-based centralized monitoring system of adherence to immunosuppressive medication in kidney transplant recipients: study protocol for a randomized controlled trial
Creators: name: Hee-Yeon Jung
name: Seong, Sook
name: Choi, Ji-Young
name: Cho, Jang-Hee
name: Park, Sun-Hee
name: Chan-Duck Kim
name: Yoon, Young-Ran
name: Hyung-Kee Kim
name: Huh, Seung
name: Se-Hee Yoon
name: Lee, Jong
name: Yong-Lim Kim
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Science Policy

description: SPIRIT 2013 Checklist: recommended items to address in a clinical trial protocol and related documents*. (DOC 123Â kb)
Electronic energy level alignment of dye molecules on  TiO2 and ZnO surfaces for photovoltaic applications
Creators: name: Theisen, Jean-Patrick
Publisher: name: No Publisher Supplied
Year: 2008

description: In dye-sensitized solar cells (DSSC), the attributes of the dye-semiconductor interface are of important interest. In this thesis, electronic and structural aspects of dye/semiconductor systems have been studied experimentally using ultraviolet photoemission spectroscopy (UPS), inverse photo electron spectroscopy (IPS) and scanning tunneling microscopy (STM).  In this work the electronic structure of N3, or more precisely Ru(4,4-dicarboxylate-2,2-bipyridine)2-(NCS)2, molecules absorbed on rutile TiO2(110) single crystal and anatase TiO2 nanoparticles has been studied and has shown that the energy of highest occupied molecular orbital (HOMO) of the N3 dye is located near the middle of the semiconductor band gap and that the lowest unoccupied molecular orbital (LUMO) level overlaps with the Ti 3d orbitals of the TiO2 conduction band.  A shift of the UPS/IPS energy spectra indicates the formation of an induced dipole upon N3 adsorption on the TiO2 surface.The electronic contributions of N3 in combination with ZnO are similar to N3 absorbed on TiO2. The position of the HOMO is almost identical in regard to the band edge of the valence band, but the LUMO is located a bit higher in energy in regard the conduction band minimum (CBM) as in comparison with N3/TiO2. We studied also the adsorbate isonicotinic acid (INA) with chemical structure:  C6H5NO2 on the oxides, because it is a good model for the binding ligand of the N3 molecule and which is where the spatial distribution of the N3 LUMO is expected to be delocalized. Indeed, the electronic structure of the LUMO for INA adsorbate is for both semiconductors is very similar to the LUMO of the adsorbate N3 dye.   Another dye, catechol (C6H6O2), has been reported that catechol bonds strongly to TiO2 and that electrons can be excited directly from the catechol HOMO to the conduction band of TiO2. Our experiments show that the LUMO is indeed mixed significantly with the conduction band of TiO2.A monolayer of pivalate ((CH3)3CCOO-) ions was used to protect the sample surface from contamination during the wetting process of the N3 adsorption. The effect of passivation on the quality of the semiconductor/dye interface is studied by UPS and IPS measurements.
Presidents, parties and the constitution of the people
Creators: name: West, Lee Christopher
Publisher: name: No Publisher Supplied
Year: 2008

description: This dissertation research focuses on broad questions of democratic practice and institutional design by way of examining the origins and development of presidential rhetoric.  I challenge some of the reigning assumptions about the rise of popular executive leadership in America by showing Twentieth Century practice not to be completely innovative, but to stem from the interest of the modern executive in a rhetorical defense of its interests, as anticipates in the executive theory of Machiavelli and Hobbes.  I also make the argument for Twentieth Century continuity with earlier presidential behavior toward public opinion by a natural tension between constitutionalism and theories of partisanship that stretches from Bolingbroke to Jefferson, and beyond.
Pachycondyla
Creators: name: Schmidt, C. A.
name: Shattuck, S. O.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pachycondyla

description: Species of Pachycondyla
Kempf (1961) came closest to providing a revision for true Pachycondyla. His revision and keys deal ostensibly with the Brazilian Pachycondyla fauna, but this includes all species we associate with the genus except P. lenkoi, which he described soon afterward, and also includes Neoponera magnifica and N. metanotalis, which Kempf included in Pachycondyla but which we have transferred to Neoponera.
P. constricticeps Mackay & Mackay, 2010: Argentina
P. crassinoda (Latreille, 1802): Suriname
P. fuscoatra (Roger, 1861): Colombia
P. harpax (Fabricius, 1804): “South America”
P. impressa (Roger, 1861): Colombia
P. inca Emery, 1901: Peru
P. lattkei Mackay & Mackay, 2010: Venezuela
P. lenis Kempf, 1961: Brazil
P. lenkoi Kempf, 1962: Brazil
P. purpurascens Forel, 1899: Costa Rica
P. striata Smith, F., 1858: Brazil
We have not managed to discern the proper taxonomic placement for a handful of ponerine species previously associated with Pachycondyla. In some cases this uncertainty stems from our failure to examine specimens of the species in question (especially when the original descriptions are ambiguous), while in other cases the morphological traits of the species leave doubts about its affinities. We leave these species as incertae sedis within Pachycondyla while acknowledging this placement is undoubtedly incorrect. Exact placement will require detailed examination of relevant material of these taxa.
Incertae sedis
P. curiosa Mackay & Mackay, 2010: Brazil
P. jonesii Forel, 1891: Madagascar
P. solitaria Smith, F., 1860: Indonesia
P. unicolor Smith, F., 1860: Indonesia
P. vidua Smith, F., 1857: Borneo
P. vieirai Mackay & Mackay, 2010: Ecuador
Fossil species (incertae sedis)
† P. baltica Dlussky, 2002: Baltic Amber
† P. calcarea (Théobald, 1937): France (Oligocene)
† P. conservata Dlussky, 2009: Rovno Amber
† P. crawleyi (Donisthorpe, 1920): Great Britain (Oligocene)
† P. dubia (Théobald, 1937): France (Oligocene)
† P. eocenica Dlussky & Wedmann, 2012: Germany (Eocene)
† P. globiventris (Théobald, 1937): France (Oligocene)
† P. gracilicornis (Mayr, 1868): Baltic Amber
† P. labandeirai (Dlussky & Rasnitsyn, 2002): U.S.A. (Eocene)
† P. lutzi Dlussky & Wedmann, 2012: Germany (Eocene)
† P. messeliana Dlussky & Wedmann, 2012: Germany (Eocene)
† P. minuta Dlussky & Wedmann, 2012: Germany (Eocene)
† P. minutansata (Zhang, 1989): China (Miocene)
† P. nubeculata (Zhang, 1989): China (Miocene)
† P. petiolosa Dlussky & Wedmann, 2012: Germany (Eocene)
† P. petrosa Dlussky & Wedmann, 2012: Germany (Eocene)
† P. succinea (Mayr, 1868): Baltic Amber
† P. tristis (Dlussky, 2009): Bitterfeld Amber
description: Published as part of Schmidt, C. A. & Shattuck, S. O., 2014, The Higher Classification of the Ant Subfamily Ponerinae (Hymenoptera: Formicidae), with a Review of Ponerine Ecology and Behavior, pp. 1-242 in Zootaxa 3817 (1) on pages 155-156, DOI: 10.11646/zootaxa.3817.1.1, http://zenodo.org/record/10086256
Development of target release rate concept for controlled release packaging
Creators: name: Zhu, Xuntao
Publisher: name: No Publisher Supplied
Year: 2008

description: Controlled release packaging is a technology for producing a new generation of packaging materials which can release active compounds such as antioxidants or antimicrobials in a controlled manner to enhance food safety and quality. The objective of this research is to develop a new concept called “target release rate”, which is the rate of releasing active compounds to achieve desirable results. The target release rate is a critical but a missing link for advancing this technology.The first task was to define the target release rate in a meaningful way. A syringe pump was used to release tocopherol (a natural antioxidant) into linoleic acid (a food simulant) at various rates and temperatures. Methodologies were then developed to define the target release rates based on the degradation of tocopherol (measured by high pressure liquid chromatography) and induction periods of lipid oxidation of linoleic acid (measured by UV spectrophotometer and gas chromatography). Results showed that the target release rate of tocopherol was temperature dependent, around 40, 80 and 150 ppm per day at 30, 40 and 50°C, respectively. The second task was to study the release rates of tocopherol from polymeric packaging films. Polyethylene/polypropylene polymer blended films containing tocopherol were produced by using the cast film and blown film processes. Tocopherol release rates, degradation of tocopherol, and lipid oxidation of linoleic acid were measured as the functions of time and temperature. Increasing the polypropylene ratio in the film retarded the release of tocopherol from the film but increased the induction period of lipid oxidation. The results confirmed the observation from the syringe pump experiment that degradation of tocopherol and induction period was dependent of the release rate of tocopherol. They also suggested that the release behavior of tocopherol might be manipulated by varying the polymer composition and processing conditions, with the aim of matching the desirable target release rate.Research was done to test real food, and to characterize physical properties of polymer films. Sesamol released from films increased shelf life of cereal up to 50% longer than the control. Release of tocopherol from film reduced browning of cheese spread.
title: Maintenance of core mammalian body temperature
Creators: name: Diller, Kenneth R.
name: Hensley, Daniel W.
Publisher: name: United States Patent and Trademark Office
Year: 2016
Subjects: subject: A61F7/0085
subject: A61B5/01
subject: A61B5/6814
subject: A61B5/6817
subject: A61B5/682
subject: A61F7/00
subject: A61F7/007
subject: A61F2007/0011
subject: A61F2007/0036
subject: A61F2007/0056
subject: A61F2007/0071
subject: A61F2007/0298
subject: No longer published

description: The present application relates to methods for maintaining core body temperature in a subject. Heat is applied to peripheral thermoregulatory control tissue of the subject to increase or maintain perfusion of blood in glabrous tissue of the subject, and a warming stimulus is applied to the glabrous tissue. The application of heat to the peripheral thermoregulatory control tissue occurs discretely and simultaneously with application of the warming stimulus to the glabrous tissue, without application of a heating device or a warming device to tissue other than the tissue subjected to the applied heat or to the applied warming stimulus, thereby maintaining the core body temperature of the subject.
Development of 4H-SiC high voltage unipolar power switching devices
Creators: name: Alexandrov, Petre
Publisher: name: No Publisher Supplied
Year: 2009

description: 4H-SiC is a promising material for switching high power and high temperature device applications. The superior properties of SiC, such as wider band-gap and higher value of critical electric field allow significant reduction in device on-resistance compared to Si power devices of similar voltage ratings. In addition the excellent thermal conductivity of SiC alleviates the device cooling requirements and allows design of smaller and more efficient systems. Several advantages of the unipolar power switches over the bipolar switches make them desirable for fast switching applications. Voltage-controlled normally-off devices are particularly attractive for practical applications because of simpler gate-drive circuitry. The advantages of the vertical JFET device being free of the problems related to oxide reliability, as compared to the MOSFET, recognize it as an excellent candidate for high power, high temperature switching applications. Device designs for normally-off and normally-on unipolar switches with blocking voltages from 400V to 11kV are proposed, based on a pure vertical trenched and implanted structure. Two different junction termination structures (junction termination extension and guard rings) are designed and successfully implemented. A fabrication process is designed to achieve a simple and reliable self-aligned fabrication process. The fabrication challenges are discussed and ways to improve the process are identified. Three different devices were designed and fabricated. The world’s first normally-off 4H-SiC TIVJFET with a blocking voltage of 11kV was demonstrated, showing low specific on-resistance of 124mOhm.cm2. Normally-off and normally-on 4H-SiC High Frequency TIVJFETs with blocking voltages up to 400V were demonstrated. 3.3A-397V normally-off capability was achieved for a single die, corresponding to a high power of 1310 W/die. This corresponds to a class B operation RF power of 164W for a single die. Cut-off frequency fT= 0.9 to 1.5 GHz was reached.In the 1200V class devices a normally-on 4H-SiC TIVJFET with guard ring termination and substantially simplified processing was also demonstrated. The highest blocking voltage achieved was 1562V with a specific on-resistance of 2.8mOhm.cm2 at VDS=0.5V and VGS=2.5V and a current gain of 1495. The lowest specific on resistance achieved was 2.2mOhm.cm2 at VDS=0.5V and VGS=2.5V with a current gain of 1454 and a blocking voltage of 1232V.
Acrocyusa forticornis Pace 2009, n. sp.
Creators: name: Pace, Roberto
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Acrocyusa
Acrocyusa forticornis

description: Acrocyusa forticornis n. sp.
(Figg. 104-105)
Materiale tipico: Holotypus , Brasilien, Nova Teutonia, VII.1955 - XI.1955, 300- 500 m, leg. Plaumann (MB).
Paratypi: 3 , stessa provenienza (MB), (MRSNT).
Descrizione:
Lunghezza 3 mm. Corpo lucidissimo e rossiccio, con quarto urotergo libero bruno-rossiccio; antenne bruno-rossicce con i due antennomeri basali giallo-rossicci; zampe rossicce. Punteggiatura del capo evidente e assente sulla fascia longitudinale mediana, quella del pronoto fine e molto superficiale. Granulosità delle elitre saliente, quella dell’addome fine. Reticolazione assente su tutto il corpo. Quattro punti forti sul disco del pronoto. Solchi trasversi basali punteggiati. Spermateca fig. 105.
Nota:
Acrocyusa BERNHAUER, 1930, è stato descritto come sottogenere di Ocyusa KRAATZ, 1856. In questa sede è considerato genere a sé stante per le antenne molto clavate.
Comparazioni:
A motivo delle antenne fortemente clavate, la nuova specie è simile ad A. grandicornis BERN- HAUER, 1930, del Congo. Se ne distingue per avere il corpo rossiccio con quarto urotergo libero bruno-rossiccio (nero e nero-bruno in grandicornis), per l’undicesimo antennomero brunorossiccio e non giallo-rossiccio come in grandicornis, per gli occhi molto più corti delle tempie (occhi lunghi quanto le tempie in grandicornis) e per l’undicesimo antennomero lungo quanto i quattro precedenti riuniti (il medesimo poco più lungo dei due antennomeri precedenti riuniti in grandicornis).
Etimologia: Il nome della nuova specie significa «antenne forti» a motivo delle sue robuste antenne.
description: Published as part of Pace, Roberto, 2009, Nuovi dati faunistici e tassonomici su Aleocharinae delle tribù Lomechusini, Hoplandriini, Oxypodini e Aleocharini del Sudamerica (Coleoptera, Staphylinidae), pp. 133-173 in Beiträge Zur Entomologie = Contributions to Entomology 59 (1) on pages 164-165, DOI: 10.21248/contrib.entomol.59.1.133-173, http://zenodo.org/record/4752253
title: Underwater noise abatement panel and resonator structure
Creators: name: Lee, Kevin M.
name: Wochner, Mark S.
name: Wilson, Preston
name: Mendez Martinez, Hector L.
Publisher: name: United States Patent and Trademark Office
Year: 2016
Subjects: subject: G10K11/172
subject: G10K2200/11
subject: No longer published

description: A system for reducing noise emissions in underwater environments is presented. The system can be extended to applications in any two-fluid environments where one fluid (gas) is contained in an enclosed resonator volume connected to the outside environment at an open end of the resonator body. The resonators act as gas-containing (e.g., air) Helmholtz resonators constructed into solid panels that are submerged in the fluid medium (e.g., sea water) in the vicinity of a noise generating source. The oscillations of the trapped air volume in the resonators causes reduction of certain noise energy and a general reduction in the transmitted noise in the environment of the system.
Discretization of continuous features by human learners
Creators: name: Aitkin, Cordelia D.
Publisher: name: No Publisher Supplied
Year: 2009

description: Natural features are often continuous, but many models of human learning and categorization involve discrete-valued (e.g. Boolean) features. Discretization is well-known to be beneficial in machine learning, leading to faster and sometimes more accurate learning. Yet there has been little research on how human learners discretize continuous features. This dissertation investigates human discretization, focusing on two specific areas of inquiry. First is the hypothesis that discretization of a continuous parameter depends on the shape of the probability distribution underlying it, and principally on the presence of “modes” or separable peaks in the distribution. The second hypothesis is that humans create clear distinctions between discretized feature values, rather than probabilistic boundaries.Subjects were presented with items that had feature values drawn from a mixture of Gaussian distributions, and a free sorting task was used to assess whether subjects spontaneously discretized the feature in a way that related to the underlying mixture. The relative locations of the two component Gaussians, their separation as measured by Cohen’s d (the ratio of the distance between the components’ means to their standard deviations), and the number of items drawn from the overall mixture were varied. Each of these factors influenced the way subjects discretized the features, while further analysis showed that the estimated mixtures were more sharply separated (higher Cohen’s d) than the original probability. This study suggests that human featural discretization involves a process akin to the estimation of mixture components in the environment, but that the separation among the components is systematically overestimated to create “cleaner” divisions than are truly present—a phenomenon that might be termed hyperdiscretization.
Additional file 12: of Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells
Creators: name: Schweizer, Patrick
name: Darche, Fabrice
name: Ullrich, Nina
name: Geschwill, Pascal
name: Greber, Boris
name: Rivinius, Rasmus
name: Seyler, Claudia
name: MĂźller-Decker, Karin
name: Draguhn, Andreas
name: Utikal, Jochen
name: Koenen, Michael
name: Katus, Hugo
name: Thomas, Dierk
Publisher: name: Figshare
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Overview of nodal lineage differentiation protocols in embryonic stem cells. (DOC 399 kb)
title: Methods for fine particle manufacture
Creators: name: Smyth, Hugh D.
name: Herpin, Matthew
Publisher: name: United States Patent and Trademark Office
Year: 2016
Subjects: subject: A61K31/496
subject: A61K9/14
subject: A61K9/145
subject: A61K31/192
subject: A61K2300/00
subject: No longer published

description: Processes for preparing micronized particles comprising a poorly water soluble bioactive agent are provided. The processes utilize a superheated aqueous phase which can serve as the continuous phase of an emulsion. The superheated aqueous phase can be used to melt poorly water soluble bioactive agents and/or matrix materials which them form molten droplets dispersed within the superheated aqueous phase. The size and size distribution of the molten droplets can be controlled using a variety of suitable methods. The molten droplets can then be cooled to form micronized particles comprising the poorly water soluble bioactive agent. If desired, the cooling rate can be selected to control the crystalline morphology of the resulting micronized particles.
The mediating role of risk proneness on the ecology of adolescent health risk behavior
Creators: name: Agre, Lynn Ann
Publisher: name: No Publisher Supplied
Year: 2009

description: The co-occurrence of sexual behavior and substance use among adolescents–both licit and illicit–is well substantiated in the socio-medical literature. However, limited studies have been published which focus on the context and psychosocial relationships which predispose youth to engage in risk behavior. The interaction between environment and health risk behavior during teen years can set the stage for later-life deleterious health outcomes. Thus, this research examines how adolescent self-rated risk proneness in conjunction with underlying psychosocial mechanisms predicts the likelihood of engaging in concurrent sexual behavior and alcohol use. The current literature has demonstrated the strong association between the co-occurrence of illicit drug use and sexual behavior. However, tantamount to this relationship are, psychosocial factors which, when examined concomitant with health risk behaviors grouped  by maternal educational attainment, will help elucidate differences between categories of youth at risk for compromised mental and physical well-being.  The Bronfenbrenner ecological framework is utilized to substantiate the relevance of health risk behaviors, environment and the importance of studying psychosocial factors in multivariate models. The data selected for analysis to both demonstrate these relationships and identify risk profiles originate from the National Longitudinal Survey of Youth (NLSY), Young Adult 1998 cohort. Partitioning the NLSY 1998 cohort by mother’s education tests how risk proneness as a mediator differs by maternal highest grade completed, as it affects adolescent deleterious behavior. These data are renowned for an oversampling of African Americans and are nationally representative of other ethnic groups such as Hispanics and Asians, requiring the application of an algebraic weight to normalize against the US population. Therefore, the key findings discovered in this study are: (1) the mediational effect  in the pathway to health risk behaviors is risk proneness; (2) reported depressive illness symptoms are the underlying mechanism of risk proneness; (3) the path model is robust when tested among different groups using the Bronfenbrenner ecosystem paradigm; and (4) the weighting technique is vital to preserving the original distribution of the population, since the study sample needs to reflect the actual proportion of  racial/ethnic groups in the US population.
title: Method and apparatus for determining cardiac performance in a patient with a conductance catheter
Creators: name: Feldman, Marc D.
name: Valvano, Jonathan W.
name: Pearce, John A.
name: Wei, Chia-Ling
Publisher: name: United States Patent and Trademark Office
Year: 2016
Subjects: subject: A61B5/0538
subject: A61B5/02007
subject: A61B5/0215
subject: A61B5/029
subject: A61B5/053
subject: No longer published

description: An apparatus for determining cardiac performance in the patient. The apparatus includes a conductance catheter for measuring conductance and blood volume in a heart chamber of the patient. The apparatus includes a processor for determining instantaneous volume of the ventricle by applying a non-linear relationship between the measured conductance and the volume of blood in the heart chamber to identify mechanical strength of the chamber. The processor is in communication with the conductance catheter. Methods for determining cardiac performance in a patient. Apparatuses for determining cardiac performance in a patient.