cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Anharmonicity strongly enhancing thermal interface conductance: A new anharmonic atomistic Green's function formalism
Creators: name: Dai, Jinghang
name: Tian, Zhiting
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The traditional atomistic Green's function (AGF) was formulated in the harmonic regime, preventing it from capturing the role of anharmonicity in interfacial thermal transport. Incorporating anharmonicity into AGF has long been desired but remains challenging. We developed a rigorous anharmonic AGF model to incorporate anharmonicity at interfaces in 3-D structures with first-principles force constants. Thermal conductance of silicon- and aluminum-based interfaces is significantly enhanced resulting from the new channels opened by inelastic scattering. This work represents a major step forward for AGF and highlights the importance of anharmonicity at the interface.
description: 9 pages, 3 figures
Exploring the potential of Andrographis paniculata for developing novel HDAC inhibitors: an in silico approach
Creators: name: Das, Debalina
name: Banerjee, Ritesh
name: Bandyopadhyay, Maumita
name: Nag, Anish
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: Cancer is one of the dreaded diseases of the twentieth century, emerging the major global causes of human morbidity. Cancer research in the last 15 years has provided unprecedented information on the role of epigenetics in cancer initiation and progression. Histone deacetylases (HDACs) are recognized as important epigenetic markers in cancer, whose overexpression leads to increased metastasis and angiogenesis. In the current study, thirty-four (34) compounds from Andrographis paniculata were screened for the identification of potential candidate drugs, targeting three Class I HDACs (Histone deacetylases), namely HDAC1 (PDB id 5ICN), HDAC3 (PDB id 4A69) and HDAC8 (PDB id 5FCW) through computer-assisted drug discovery study. Results showed that some of the phytochemicals chosen for this study exhibited significant drug-like properties. In silico molecular docking study further revealed that out of 34 compounds, the flavonoid Andrographidine E had the highest binding affinities towards HDAC1 (−9.261 Kcal mol−1) and 3 (−9.554 Kcal mol−1) when compared with the control drug Givinostat (-8.789 and −9.448 Kcal mol−1). The diterpenoid Andrographiside displayed the highest binding affinity (-9.588 Kcal mol−1) to HDAC8 compared to Givinostat (-8.947 Kcal mol−1). Statistical analysis using Principal Component Analysis tool revealed that all 34 phytocompounds could be clustered in four statistical groups. Most of them showed high or comparable inhibitory potentials towards HDAC target protein. Finally, the stability of top-ranked complexes (Andrographidine E-HDAC1 and HDAC3; Andrographiside-HDAC8) at the physiological condition was validated by Molecular Dynamic Simulation and MM-PBSA study.
title: Design optimisation for 3D printing of a biomedical implant
title: Βελτιστοποίηση Μελέτης και Τρισδιάστατη Εκτύπωση Βιοϊατρικού Εμφυτεύματος

Creators: name: Πανιερακη Αργυρω
Publisher: name: Technical University of Crete
Year: 2022

description: The present master dissertation examines the optimisation of a biomedical 3D printed implant study. The finite element method (FEM) is used to discretise the model of an implant made from a human shoulder blade (scapular). Simulations are performed using the Computer-Aided Design (CAD) software Siemens NX, specifically the NX Nastran solver. This work is intended to reduce implant mass and create a personalised geometry that considers the anatomy of the patient. Topological optimisation (TO) is employed, and Ti-6Al-4V is chosen as the implant's material. The different operating conditions, manufacturing constraints, and application of forces/loads at points where bone stress is applied are studied. Next, the design goal is established, which is to reduce the mass in order to allow tissue regeneration. The results show the distribution of the material. When the results are displayed, the redistribution of the material is visible, and then the lattice structure is added. Later, the printing simulation was conducted where the overlapping layers are simulated using the Direct Energy Deposition (DED) 3D printing method. Unfortunately, the real object was not able to be 3D printed.
description: Στην παρούσα μεταπτυχιακή διατριβή μελετάται η βελτιστοποίηση μελέτης βιοϊατρικού εμφυτεύτος για τρισδιάστατη εκτύπωση. Το εξεταζόμενο σχεδιαστικό μοντέλο αποτελεί ένα εμφύτευμα οστού ανθρώπινης ωμοπλάτης. Η διακριτοποίηση του μοντέλου γίνεται με τη μέθοδο των πεπερασμένων στοιχείων. Οι προσομοιώσεις γίνονται στο σχεδιαστικό περιβάλλον «Siemens NX». Στόχο της εργασίας αποτελεί η μείωση της μάζας του εμφυτεύματος και η σχεδίαση εξατομικευμένης γεωμετρίας βάσει της ανατομίας του ασθενή. Γινεται χρήση της μεθόδου της τοπολογικής βελτιστοποίησης και ως υλικό του μοντέλου επιλέγεται το Ti–6Al–4V. Αρχικά γίνεται διερεύνηση των διαφορετικών σεναρίων για τις συνθήκες λειτουργίας, τους κατασκευατικούς περιορισμούς, την εφαρμογή των δυνάμεων/φορτίσεων στα σημεία του οστού που δέχεται καταπόνηση και τον καθορισμό οριακών συνθηκών. Κατόπιν, ορίζεται ο σχεδιαστικός στόχος που είναι η μείωση της μάζας, δίνοντας τη δυνατότητα ανάπλασης των ιστών. Κατά την εμφάνιση των αποτελεσμάτων, είναι ορατή η ανακατανομή του υλικού και έπειτα προστίθεται η πλεγματική δομή. Ακολούθως μέσω του λογισμικού που παρέχεται από τον τρισδιάστατο εκτυπωτή μετάλλου της εταιρείας Meltio3d© , γίνεται η προσομοίωση της εκτύπωσης σε επάλληλες στρώσεις μέσω της μεθόδου άμεσης εναπόθεσης ενέργειας (DED).
Low-Temperature Specific Heat of an Extreme-Type-II Superconductor at High Magnetic Fields
Creators: name: Carr, A. L.
name: Trafton, J. J.
name: Dukan, S.
name: Tesanovic, Z.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We present a detailed study of the quasiparticle contribution to the low-temperature specific heat of an extreme type-II superconductor at high magnetic fields. Within a T-matrix approximation for the self-energies in the mixed state of a homogeneous superconductor, the electronic specific heat is a linear function of temperature with a linear-$T$ coefficient $γ_s(H)$ being a nonlinear function of magnetic field $H$. In the range of magnetic fields $H\agt (0.15-0.2)H_{c2}$ where our theory is applicable, the calculated $γ_s(H)$ closely resembles the experimental data for the borocarbide superconductor YNi$_2$B$_2$C.
description: 7 pages, 2 figures, to appear in Physical Review B
Anisopodus bellus Martins & Monne 1974
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Anisopodus
Anisopodus bellus

description: 6. Anisopodus bellus Martins & Monné, 1974
Type locality — Brazil, Minas Gerais: Lavras. (MZSP). Distribution — Brazil (Minas Gerais to São Paulo).
 Anisopodus bellus Martins & Monné, 1974a: 17, fig. 7.
description: Published as part of Monné, Miguel A., 2005, Catalogue of the Cerambycidae (Coleoptera) of the Neotropical Region. Part II. Subfamily Lamiinae, pp. 1-760 in Zootaxa 1023 (1) on pages 1-760, DOI: 10.11646/zootaxa.946.1.1, http://zenodo.org/record/5049553
Critical theories for the pseudogap Kondo problem
Creators: name: Fritz, Lars
name: Kircan, Marijana
name: Vojta, Matthias
Publisher: name: arXiv
Year: 2004
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We discuss quantum phase transitions in the pseudogap Kondo problem, which describes a magnetic moment coupled to conduction electrons with a power-law density of states, rho(omega) ~ |omega|^r. We show that different perturbative expansions, together with renormalization group techniques, provide effective low-energy field theories for the relevant critical fixed points. In particular, we review expansions near the lower-critical and upper-critical dimensions of the problem, being r=0 and r=1, respectively.
description: 2 pages, 1 fig, submitted to SCES04 proceedings
The modified tetrahedron equation and its solutions
Creators: name: von Gehlen, G.
name: Pakuliak, S.
name: Sergeev, S.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A large class of 3-dimensional integrable lattice spin models is constructed. The starting point is an invertible canonical mapping operator in the space of a triple Weyl algebra. This operator is derived postulating a current branching principle together with a Baxter Z-invariance. The tetrahedron equation for this operator follows without further calculations. If the Weyl parameter is taken to be a root of unity, the mapping operator decomposes into a matrix conjugation and a C-number functional mapping. The operator of the matrix conjugation satisfies a modified tetrahedron equation (MTE) in which the "rapidities" are solutions of a classical integrable Hirota-type equation. The matrix elements of this operator can be represented in terms of the Bazhanov-Baxter Fermat curve cyclic functions, or alternatively in terms of Gauss functions. The paper summarizes several recent publications on the subject.
description: 24 pages, 6 figures using epic/eepic package, Contribution to the proceedings of the 6th International Conference on CFTs and Integrable Models, Chernogolovka, Spetember 2002, reference added
A RATIONAL EXPECTATIONS MODEL OF INVENTORY HOLDING UNDER RISK AND UNCERTAINTY
Creators: name: Glauber, Joseph W.
name: Miranda, Mario J.
name: Glauber, Joseph W.
name: Miranda, Mario J.
Publisher: name: Unknown
Year: 1986
Subjects: Crop Production/Industries
Production Economics
Risk and Uncertainty

description: In this paper a model of inventory holding under risk and uncertainty is developed and introduced into a model of the U.S. soybean market. Through simulation experiments the effects of risk on price levels and stability are measured and the welfare effects on producers, consumers and inventory holders are discussed.
Subject selection, Demographics, and ipApEn Results from Uncovering complex central autonomic networks at rest: a functional magnetic resonance imaging study on complex cardiovascular oscillations
Creators: name: Valenza, Gaetano
name: Passamonti, Luca
name: Duggento, Andrea
name: Toschi, Nicola
name: Barbieri, Riccardo
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Biological Engineering
subject: 60114 Systems Biology
subject: FOS: Biological sciences
subject: 60199 Biochemistry and Cell Biology not elsewhere classified
subject: 69999 Biological Sciences not elsewhere classified

description: This study aims to uncover brain areas that are functionally linked to complex cardiovascular oscillations in resting-state conditions. Multi-session functional magnetic resonance imaging (fMRI) and cardiovascular data were gathered from 34 healthy volunteers recruited within the human connectome project (the ‘100-unrelated subjects' release). Group-wise multi-level fMRI analyses in conjunction with complex instantaneous heartbeat correlates (entropy and Lyapunov exponent) revealed the existence of a specialized brain network, i.e. a complex central autonomic network (CCAN), reflecting what we refer to as complex autonomic control of the heart. Our results reveal CCAN areas comprised the paracingulate and cingulate gyri, temporal gyrus, frontal orbital cortex, planum temporale, temporal fusiform, superior and middle frontal gyri, lateral occipital cortex, angular gyrus, precuneous cortex, frontal pole, intracalcarine and supracalcarine cortices, parahippocampal gyrus and left hippocampus. The CCAN visible at rest does not include the insular cortex, thalamus, putamen, amygdala and right caudate, which are classical CAN regions peculiar to sympatho-vagal control. Our results also suggest that the CCAN is mainly involved in complex vagal control mechanisms, with possible links with emotional processing networks.
Network pharmacology, molecular docking-driven, Qbd-Engineered antifungal in-situ gel loaded with voriconazole nanostructured lipid carriers
Creators: name: Tiwari, Abhishek
name: Tiwari, Varsha
name: Palaria, Binita
name: Aslam, Ramsha
name: Kumar, Manish
name: Kumar, Neeraj
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Biochemistry
Space Science
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Fungal infections (FIs) affect majority of the population, but the current treatments face challenges in terms of their effectiveness. This study focused on specific fungal targets, including dihydrofolate reductase (DHFR), acetohydroxy-acid synthase (AHAS), farnesyltransferase and endoglucanase. The docking studies were conducted with the drug voriconazole (VCZ), comparing it with Fluconazole (FCZ) and Amphotericin B (ATB) against 11 protein data bank (PDB) IDs (IDYR, 3NZB, 6DEQ, 1KS5, 7T0C, 1FY4, 5AJH, 7R79, 6TZ6 and 6IDY). Molecular dynamics (MD) analysis, including RMSD, RMSF, PCA and FEL, confirmed the stability of VCZ. The solubility of VCZ was a problem, so nanostructured lipid carriers (NLCs) were developed to improve ocular penetration. VCF5 was the optimized formulation by using 32 full factorial design. VCZF5-NLCs were the best in terms of nanoparticle size (126.6 nm), Zeta potential (33.5 mV), drug content (DC; 97.38 ± 0.210), encapsulation efficiency (EE; 88.01 ± 0.272) and extended drug release. The results of the ex-vivo corneal diffusion study indicate that VCZ-NLC-loaded in-situ gel (VCZ-NLC-IG3) exhibited DC of 88.25% and drug entrapment (DE) of 74.2%. The results of the zone of inhibition indicated that VCZ-NLC-IG3 had superior efficacy compared to ATB. Network pharmacology showed VCZ interacts with the genes which are responsible for fungus ergosterol biosynthesis, including lanosterol 14-alpha demethylase inhibitors (ERG11), ergosterol biosynthesis protein 5 (ERG5), dimethylallyltransferase 2 (DIT2), ketosynthase (KCN), methylsterol monooxygenase (MSMO1), lamin B receptor (LBR), squalene epoxidase (SQLE), 3-hydroxy-3-methylglutaryl-coenzyme A Reductase (MGCR), 3-hydroxy-3-methylglutaryl-coenzyme A Synthase (HMGCS) and 3-keto-steroid reductase (HSD17B7). In conclusion, the optimized VCZ-loaded NLCs present a promising approach to treat ocular FIs.
Effects of Pilates Exercises in Low Back Pain: A Systematic Review
Creators: name: Ballard, Beth
name: Carey, Tina
name: Clayton, Gillian
name: Lenz, Angela
name: Mayall, Erika
name: Wall, Mike
name: Dean, Elizabeth
name: Westby, Marie
Publisher: name: The University of British Columbia
Year: 2007

description: MPT Systematic Reviews and Research Projects.
Nonleptonic $Λ_b$ decays to $D_s(2317)$, $D_s(2460)$ and other final states in Factorization
Creators: name: Datta, Alakabha
name: Lipkin, Harry J.
name: O'Donnell, Patrick J
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We consider nonleptonic Cabibbo--allowed $Λ_b$ decays in the factorization approximation. We calculate nonleptonic decays of the type $ Λ_b \to Λ_c P $ and $ Λ_b \to Λ_c V $ relative to $\bar{B}_d \to D^+ P$ and $\bar{B}_d \to D^+ V$ where we include among the pseudoscalar states(P) and the vector states(V) the newly discovered $D_s$ resonances, $D_s(2317)$ and $D_s(2460)$. In the ratio of $Λ_b$ decays to $D_s(2317)$ and $D_s(2460)$ relative to the $\bar{B}_d$ decays to these states, the poorly known decay constants of $D_s(2317)$ and $D_s(2460)$ cancel leading to predictions that can shed light on the nature of these new states. In general, we predict the $Λ_b$ decays to be larger than the corresponding $\bar{B}_d$ decays and in particular we find the branching ratio for $Λ_b \to Λ_c D_s(2460)$ can be between four to five times the branching ratio for $\bar{B}_d \to D^+ D_s(2460)$. This enhancement of $Λ_b$ branching ratios follows primarily from the fact that more partial waves contribute in $Λ_b$ decays than in $\bar{B}_d$ decays. Our predictions are largely independent of model calculations of hadronic inputs like form factors and decay constants.
description: 16 pages LaTeX
Level spacing statistics of classically integrable systems -Investigation along the line of the Berry-Robnik approach-
Creators: name: Makino, H.
name: Tasaki, S.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: By extending the approach of Berry and Robnik, the limiting level spacing distribution of a system consisting of infinitely many independent components is investigated. The limiting level spacing distribution is characterized by a single monotonically increasing function $\barμ(S)$ of the level spacing $S$. Three cases are distinguished: (i) Poissonian if $\barμ(+\infty)=0$, (ii) Poissonian for large $S$, but possibly not for small $S$ if $0
description: 19 pages, 4 figures. Accepted for publication in Phys. Rev. E
Insights into the molecular mechanism of dextran sulfate inhibiting DNA digestion by pepsin: a crucial role of sulfate group on the binding to DNA
Creators: name: Zhang, Jing
name: Ding, Leshan
name: Hou, Hu
name: Yu, Long
name: Li, Jing
name: Dong, Ping
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Sulfate polysaccharides can inhibit DNA digestion in simulated gastric juice in vitro, which is important for regulating dietary nucleic acids metabolism, but the mechanism of inhibition is unclear. This study used dextran sulfate (DS) with different sulfate groups and molecular weights to explore the effect of DS on DNA digestion. Molecular interactions between DS and DNA were investigated by biolayer interferometry (BLI), isothermal titration calorimetry (ITC) and molecular dynamics simulations. Results indicated that DS with higher molecular weight and sulfate group content showed stronger inhibitory effect of DNA digestion. ITC results showed that the combined Kd value of DNA and DS was about 2.53 mM. The main reason for inhibition of DNA digestion is that the formation of hydrogen bonds between the sulfate group of DS and DNA bases hinders the binding of DNA to pepsin. This finding will facilitate new strategies for nucleic acid metabolism and oral drug delivery.
THE CROP INSURANCE DECISION: LENDERS AND PRODUCERS PREFERENCES
Creators: name: Leathan, David J.
name: Richardson, James W.
name: McCarl, Bruce A.
name: Leathan, David J.
name: Richardson, James W.
name: McCarl, Bruce A.
Publisher: name: Unknown
Year: 1986
Subjects: Agricultural and Food Policy
Crop Production/Industries

description: The effect of the producer's choice of crop insurance was evaluated at both the producer and lender performance levels. Whole-farm, Monte Carlo simulations for Texas wheat/sorghum operations were completed over a six year period beginning in 1985. Results indicate crop insurance would be preferred by moderately risk averse producers when the probability of firm failure was positive or the insurance loss ratio approached one. A lender preferred the use of crop insurance whenever the probability of firm bankruptcy was nonzero and was indifferent otherwise.
Insight to phytochemical investigation and anti-hyperlipidemic effects of Eucalyptus camaldulensis leaf extract using in vitro, in vivo and in silico approach
Creators: name: Hussain, Hafiza Arbab
name: Islam, Muhammad
name: Saeed, Hamid
name: Ahmad, Abrar
name: Hussain, Anam
name: Rafay, Muhammad Zohaib
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer

description: Hyperlipidemia is a key risk factor mainly for hypertension and cardiac abnormalities. Previously eucalyptus plant (river red gum) had been used for its medicinal value for the treatment of many ailments. This study focused on phytochemical examination, investigation of an in vitro potential and in vivo effects in mice fed with high cholesterol diet, GC-MS analysis of extracts of Eucalyptus camaldulensis leaves and further confirmation of anti-hyperlipidemic potential of different constituents of plant extracts by using in silico technique. For in vitro study screening of different extracts of Eucalyptus camaldulensis leaves was performed by using pancreatic lipase enzyme inhibition assay. Ethanolic extract presented the highest potential among all the extracts by inhibiting pancreatic lipase having IC50–11.88 µg/mL. For in vivo study mice were fed with high cholesterol diet for induction of Hyperlipidemia. Water extract showed great anti-hyperlipidemic potential by reducing the level of cholesterol, triglycerides, low density lipoproteins and increasing high density lipoproteins level significantly (p < 0.05). Moreover, molecular docking and prime MM-GBSA study were applied for screening of compounds having anti-hyperlipidemic potential which showed that Alpha-cadinol was the lead compound for inhibition of pancreatic lipase enzyme having docking score (-6.604). The ADMET properties and toxicity profile of the top docked compounds were also detailed for ensuring their safety aspects. In this way in silico analysis substantiate the experimental findings by showing anti-hyperlipidemic potential in constituents of eucalyptus plant. Thus, there is a need of advanced research for isolation of active constituents having said anti-hyperlipidemic potential in the Eucalyptus camaldulensis plant.
Supplementary Methods and Results from Evolution of fossorial locomotion in the transition from tetrapod to snake-like in lizards
Creators: name: Morinaga,
name: Bergmann, Philip J.
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 110601 Biomechanics
subject: FOS: Health sciences

description: More detailed field methods, statistical analyses, and their results
Anisopodus callistus Bates 1881
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Anisopodus
Anisopodus callistus

description: 8. Anisopodus callistus Bates, 1881
Type locality — Guatemala, El Quiché: Quiché Mountains. (BMNH). Distribution — Guatemala, Costa Rica.
 Anisopodus callistus Bates, 1881a: 164; Chemsak & Linsley, 1970: 408 (lect.); Chemsak et al., 1992: 134 (cat.).
description: Published as part of Monné, Miguel A., 2005, Catalogue of the Cerambycidae (Coleoptera) of the Neotropical Region. Part II. Subfamily Lamiinae, pp. 1-760 in Zootaxa 1023 (1) on pages 1-760, DOI: 10.11646/zootaxa.946.1.1, http://zenodo.org/record/5049553
Relativistic approach to electromagnetic imaging
Creators: name: Budko, Neil
Publisher: name: arXiv
Year: 2004
Subjects: subject: Classical Physics (physics.class-ph)
subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: A novel imaging principle based on the interaction of electromagnetic waves with a beam of relativistic electrons is proposed. Wave-particle interaction is assumed to take place in a small spatial domain, so that each electron is only briefly accelerated by the incident field. In the one-dimensional case the spatial distribution of the source density can be directly observed in the temporal spectrum of the scattered field. Whereas, in the two-dimensional case the relation between the source and the spectrum is shown to be approximately the Radon transform.
description: 10 pages, 1 figure
Electronic Supplementary Material from How migratory populations become resident
Creators: name: Zoeten, Tiago De
name: Pulido, Francisco
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 60801 Animal Behaviour

description: Detailed description of simulation model, Input parameter choice, Additional references, Figures S1-S5, Tables S1-S5, R code for simulation model
title: 02_0284
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
An inverse problem to determine the shape of a human vocal tract
Creators: name: Aktosun, Tuncay
name: Sacks, Paul
name: Xu, Xiao-Chuan
Publisher: name: arXiv
Year: 2020
Subjects: subject: Mathematical Physics (math-ph)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences
subject: 34A55, 35R30, 76Q05

description: The inverse problem of determining the cross-sectional area of a human vocal tract during the utterance of a vowel is considered. The frequency-dependent boundary condition at the lips is expressed in terms of the acoustic impedance of a vibrating piston on an infinite plane baffle. The corresponding pressure at the lips is expressed in terms of the normalized impedance and a key quantity related to the so-called Jost function of an associated Schrödinger equation. Various input data sets are considered to solve the inverse problem, including the pressure at the lips, the absolute pressure at the lips, or the poles of the pressure at the lips. The solution to the inverse problem is obtained with the help of the Gel'fand-Levitan method for the associated Schrödinger equation.
description: 48 pages, 2 figures
A Systematic Review of the Effectiveness of Eccentric Strength Training in Prevention of Hamstring Strains in Healthy Individuals
Creators: name: Beers, Amanda
name: Cheong, Krystina
name: Grant, Andrew
name: Hibbert, Osita
name: Moizumi, Trevor
name: Redenbach, Darlene
Publisher: name: The University of British Columbia
Year: 2007

description: MPT Systematic Reviews and Research Projects.
A COMPARISON OF CATTLE FEEDING PROFIT VARIANCE INDICATED BY PRIVATE VERSUS PUBLIC DATA
Creators: name: Trapp, James N.
name: Webb, Jeane K.
name: Trapp, James N.
name: Webb, Jeane K.
Publisher: name: Unknown
Year: 1986
Subjects: Agricultural and Food Policy
Livestock Production/Industries
Public Economics

description: The variance of net profits calculated from USDA fixed coefficient budgets and from industry variable production coefficient pen closeout data were found to be equal. The industry variance was not higher because the variations of the prices and quantities whose products form the components of net profit are negatively correlated.
Agricultural Policy, Technology Adoption, and Farm Structure
Creators: name: Teigen, Lloyd D.
name: Teigen, Lloyd D.
Publisher: name: Unknown
Year: 1988
Subjects: subject: Agricultural and Food Policy
subject: Research and Development/Tech Change/Emerging Technologies
subject: Technology
subject: diffusion
subject: policy
subject: simulation
subject: structure
subject: adjustments

description: The linkages among farm policy instruments, technological introduction and adoption, and the structure of agriculture are illustrated in an economic model. The model shows that policy merely delays, but cannot prevent, the consequences of technological advance. New technology permits fewer farms to produce more output at lower cost, and ultimately About the same per-farm profit, than possible under the old technology. Producer-preserving policies encourage more farms to adopt the new technology than the market will support and impose adjustment costs as these farms exit after switching technologies rather than directly leaving the sector. Exit annuity payments could facilitate the adjustment process at less than one-third the cost of current program instruments, and benefit both the exiting farmers and those who remain in business.
Variable stepsize Runge-Kutta methods for stochastic wave equations
Creators: name: Wilkie, Joshua
name: Cetinbas, Murat
Publisher: name: arXiv
Year: 2004
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We show that existing Runge-Kutta methods for ordinary differential equations (odes) can be modified to solve stochastic differential equations (sdes) with strong solutions provided that appropriate changes are made to the way stepsizes are selected. The order of the resulting sde scheme is half the order of the ode scheme. Specifically, we show that an explicit 9th order Runge-Kutta method (with an embedded 8th order method) for odes yields an order 4.5 method for sdes which can be implemented with variable stepsizes. This method is tested by solving systems of sdes originating from stochastic wave equations arising from master equations and the many-body Schroedinger equation.
description: 5 figures
HDAC inhibition by Nigella sativa L. sprouts extract in hepatocellular carcinoma: an approach to study anti-cancer potential
Creators: name: Algaissi, Abdullah
name: Tabassum, Heena
name: Khan, Elhan
name: Dwivedi, Sonam
name: Lohani, Mohtashim
name: Khamjan, Nizar A.
name: Farasani, Abdullah
name: Ahmad, Iffat Zareen
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: A wide variety of natural products have been widely used in chemoprevention therapy because they have antioxidant, anti-inflammatory, and anticancer activity. In the present study, we shed light on the 5th day germinated sprouts of N. sativa seeds and evaluated them against HDAC inhibition and antioxidant activity. The extract from the seed and sprout was extracted and characterised by LC-MS/MS, FTIR, and NMR to reveal its chemical composition, especially thymol (THY) and thymoquinone (TQ). Hepatocellular carcinoma (HCC) is a global health concern as it is a major lifestyle disease. Hence, incorporating herbal-based therapeutic compounds into everyday routines has become an attractive alternative for preventing hepatic diseases. Histone deacetylase (HDAC) inhibition (HDACi) is emerging as a promising therapeutic strategy for managing various carcinomas including HCC. Therefore, the 5th day of N. sativa can be used as a potential anticancer agent by inhibiting HDAC activity, as it is reported to have an important role in the management of oxidative stress. The bioactive compound of N. sativa, i.e. thymoquinone, also showed a good binding affinity with the HDAC protein (3MAX) with a stable interaction in an in silico study as compared to the standard drug (Trichostatin A) and thymol.
CLARIN CMDI use case and flexible metadata schemes
Creators: name: Tykhonov, Slava
Publisher: name: Zenodo
Year: 2021
Subjects: clarin, clariah, cmdi, language formats, semantic web, data archive

description: CLARIAH interest group Linked Open Data, 4 November 2021. Presentation on the latest developments for Dataverse FAIR data repository. Building SEMAF workflow with external controlled vocabularies support and Semantic API. Using the theory of inventive problem solving TRIZ for the further innovation in Linked Data.
Anisopodus cognatus Bates 1863
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Anisopodus
Anisopodus cognatus

description: 9. Anisopodus cognatus Bates, 1863
Type locality — Brazil, Amazonas: São Paulo de Olivença. (MNHN). Distribution — Brazil (Amazonas).
 Anisopodus cognatus Bates, 1863: 284.
description: Published as part of Monné, Miguel A., 2005, Catalogue of the Cerambycidae (Coleoptera) of the Neotropical Region. Part II. Subfamily Lamiinae, pp. 1-760 in Zootaxa 1023 (1) on pages 1-760, DOI: 10.11646/zootaxa.946.1.1, http://zenodo.org/record/5049553
Semi-Supervised Medical Image Segmentation via Learning Consistency under Transformations
Creators: name: Bortsova, Gerda
name: Dubost, Florian
name: Hogeweg, Laurens
name: Katramados, Ioannis
name: de Bruijne, Marleen
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: The scarcity of labeled data often limits the application of supervised deep learning techniques for medical image segmentation. This has motivated the development of semi-supervised techniques that learn from a mixture of labeled and unlabeled images. In this paper, we propose a novel semi-supervised method that, in addition to supervised learning on labeled training images, learns to predict segmentations consistent under a given class of transformations on both labeled and unlabeled images. More specifically, in this work we explore learning equivariance to elastic deformations. We implement this through: 1) a Siamese architecture with two identical branches, each of which receives a differently transformed image, and 2) a composite loss function with a supervised segmentation loss term and an unsupervised term that encourages segmentation consistency between the predictions of the two branches. We evaluate the method on a public dataset of chest radiographs with segmentations of anatomical structures using 5-fold cross-validation. The proposed method reaches significantly higher segmentation accuracy compared to supervised learning. This is due to learning transformation consistency on both labeled and unlabeled images, with the latter contributing the most. We achieve the performance comparable to state-of-the-art chest X-ray segmentation methods while using substantially fewer labeled images.
A novel synthetic peptide analog enhanced antibacterial activity of the frog-derived skin peptide wuchuanin-A1
Creators: name: Putri, Rizki Amalia
name: Rohman, Muhammad Saifur
name: Swasono, Respati Tri
name: Raharjo, Tri Joko
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: In recent years, there has been a growing focus on the development of novel antibacterial compounds for clinical applications, such as antimicrobial peptide (AMP). Among the developed AMP, wuchuanin-A1, a coil-shaped bioactive peptide derived from Odorrana wuchuanensis frog skin, has been reported to exhibit antibacterial, antifungal, and antioxidant activity, but there are limited studies on its potential as an antibacterial agent. Therefore, this study aims to molecularly modify the sequence of wuchuanin-A1 to enhance its antibacterial properties. The interaction of both the native and analog peptide with bacterial inner membranes was initially assessed using computational methods. Specific amino acid substitutions were then used to enhance the modified peptide’s antibacterial efficacy, followed by several preliminary tests to evaluate its activity. This study bridges the gap in exploring the potential of wuchuanin-A1 for antibacterial purposes, providing insights into the design of effective antimicrobial agents.
title: Extraits de la lettre d'Yves Pérotin à ses parents du 13 octobre 1944
Creators: name: Pérotin, Yves
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022

description: Extraits de la lettre d’Yves Pérotin du 13 octobre 1944 de la main de son père René Pérotin.
description: Source: GED Campus Condorcet Fonds Yves Pérotin CNRS-IHTP ARC 143 ; 3ARM-42
Néron models of intermediate Jacobians associated to moduli spaces
Creators: name: Dan, Ananyo
name: Kaur, Inder
Publisher: name: arXiv
Year: 2020
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14C30, 14C34, 14D07, 32G20, 32S35, 14D20, 14H40

description: Let $π_1:\mathcal{X} \to Δ$ be a flat family of smooth, projective curves of genus $g \ge 2$, degenerating to an irreducible nodal curve $X_0$ with exactly one node. Fix an invertible sheaf $\mathcal{L}$ on $\mathcal{X}$ of relative odd degree. Let $π_2:\mathcal{G}(2,\mathcal{L}) \to Δ$ be the relative Gieseker moduli space of rank $2$ semi-stable vector bundles with determinant $\mathcal{L}$ over $\mathcal{X}$. Since $π_2$ is smooth over $Δ^*$, there exists a canonical family $\widetildeρ_i:\mathbf{J}^i_{\mathcal{G}(2, \mathcal{L})_{Δ^*}} \to Δ^{*}$ of $i$-th intermediate Jacobians i.e., for all $t \in Δ^*$, $(\widetildeρ_i)^{-1}(t)$ is the $i$-th intermediate Jacobian of $π_2^{-1}(t)$. There exist different Néron models $\overlineρ_i:\overline{\mathbf{J}}_{\mathcal{G}(2, \mathcal{L})}^i \to Δ$ extending $\widetildeρ_i$ to the entire disc $Δ$, constructed by Clemens, Saito, Schnell, Zucker and Green-Griffiths-Kerr. In this article, we prove that in our setup, the Néron model $\overlineρ_i$ is canonical in the sense that the different Néron models coincide and is an analytic fiber space which graphs admissible normal functions. We also show that for $1 \le i \le \max\{2,g-1\}$, the central fiber of $\overlineρ_i$ is a fibration over product of copies of $J^k(\mathrm{Jac}(\widetilde{X}_0))$ for certain values of $k$, where $\widetilde{X}_0$ is the normalization of $X_0$. In particular, for $g \ge 5$ and $i=2, 3, 4$, the central fiber of $\overlineρ_i$ is a semi-abelian variety. Furthermore, we prove that the $i$-th generalized intermediate Jacobian of the (singular) central fibre of $π_2$ is a fibration over the central fibre of the Néron model $\overline{\mathbf{J}}^i_{\mathcal{G}(2, \mathcal{L})}$. In fact, for $i=2$ the fibration is an isomorphism.
description: to appear in Revista Matem\'atica Complutense
Anisopodus consimilis Aurivillius 1922
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Anisopodus
Anisopodus consimilis

description: 10. Anisopodus consimilis Aurivillius, 1922
Type locality — Peru, Junin: Chanchamayo. (NHRS). Distribution — Peru.
 Anisopodus consimilis Aurivillius, 1922c: 169.
description: Published as part of Monné, Miguel A., 2005, Catalogue of the Cerambycidae (Coleoptera) of the Neotropical Region. Part II. Subfamily Lamiinae, pp. 1-760 in Zootaxa 1023 (1) on pages 1-760, DOI: 10.11646/zootaxa.946.1.1, http://zenodo.org/record/5049553
Detailed Methods and Statistics from Cognitive appraisal in fish: stressor predictability modulates the physiological and neurobehavioural stress response in sea bass
Creators: name: M. Cerqueira
name: S. Millot
name: A. Felix
name: T. Silva
name: G.A. Oliveira
name: C. C. V. Oliveira
name: S. Rey
name: S. MacKenzie
name: R. Oliveira
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Detailed methods and main effects results
Additional file 4 of SPEAQeasy: a scalable pipeline for expression analysis and quantification for R/bioconductor-powered RNA-seq analyses
Creators: name: Eagles, Nicholas J.
name: Burke, Emily E.
name: Leonard, Jacob
name: Barry, Brianna K.
name: Stolz, Joshua M.
name: Huuki, Louise
name: BaDoi N. Phan
name: Serrato, Violeta Larios
name: Gutiérrez-Millán, Everardo
name: Aguilar-Ordoñez, Israel
name: Jaffe, Andrew E.
name: Collado-Torres, Leonardo
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Information Systems
subject: FOS: Computer and information sciences

description: Additional file 4. SNVs supplementary BED files. The common SNVs used for sample identification are stored in the BED files (A) common_missense_SNVs_hg19.bed and (B) common_missense_SNVs_hg38.bed.
Star Formation in HI Selected Galaxies I: Sample Characteristics
Creators: name: Helmboldt, J. F.
name: Walterbos, R. A. M.
name: Bothun, G. D.
name: O'Neil, K.
name: de Blok, W. J. G.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A sample of 69 galaxies with radial velocities less than 2500 km/s was selected from the HI Parkes All Sky Survey (HIPASS) and imaged in broad band B and R and narrow band H-alpha to deduce details about star formation in nearby disk galaxies while avoiding surface brightness selection effects. The sample is dominated by late-type, dwarf disks (mostly Sc and Sm galaxies) with exponential disk scale lengths of about 1 to 5 kpc. The HIPASS galaxies on average have lower star formation rates (SFRs) and are bluer and lower surface brightness than an optically selected sample. HII regions were detected in all but one of the galaxies. Many galaxies had as few as two to five HII regions. The galaxies' H-alpha equivalent widths, colors, and SFRs per unit HI mass are best explained by young mean ages (about 3 to 5 Gyr according to Schmidt Law models) with star formation histories where the SFRs were higher in the past. Comparison of the surface brightness coverage of the HIPASS galaxies with that of an optically selected sample shows that such a sample may miss about 10% of the local galaxy number density and could possibly miss as much as 3 to 4% of the SFR density. The amount lower surface brightness galaxies contribute to the total luminosity density may be insignificant, but this conclusion is somewhat dependent on how the fluxes of these objects are determined.
description: Accepted to the Astrophysical Journal
Effects of Eccentric vs. Concentric Exercise in Stimulating Muscle Hypertrophy. Strength Gains & Enhanced Performance
Creators: name: Kirk, Gregory
name: Maudie, Bob
name: McKinnon, Patrick
name: Murray, Ryan
name: Stewart, Sarah
name: Reid, Darlene
Publisher: name: The University of British Columbia
Year: 2007

description: MPT Systematic Reviews and Research Projects.
Design of new Mcl-1 inhibitors for cancer using fragments hybridization, molecular docking, and molecular dynamics studies
Creators: name: Alzain, Abdulrahim A.
name: Elbadwi, Fatima A.
name: Mukhtar, Rua M.
name: Shoaib, Tagyedeen H.
name: Abdelmoniem, Nihal
name: Miski, Samar F.
name: Ghazawi, Kholoud F.
name: Alsulaimany, Marwa
name: Mohamed, Shaimaa G. A.
name: Ainousah, Bayan E.
name: Hussein, Hazem G. A.
name: Mohamed, Gamal A.
name: Ibrahim, Sabrin R. M.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Apoptosis is a critical process that regulates cell survival and death and plays an essential role in cancer development. The Bcl-2 protein family, including myeloid leukemia 1 (Mcl-1), is a key regulator of the intrinsic apoptosis pathway, and its overexpression in many human cancers has prompted efforts to develop Mcl-1 inhibitors as potential anticancer agents. In this study, we aimed to design new Mcl-1 inhibitors using various computational techniques. First, we used the Mcl-1 receptor-ligand complex to build an e-pharmacophore hypothesis and screened a library of 567,000 fragments from the Enamine database. We obtained 410 fragments and used them to design 92,384 novel compounds, which we then docked into the Mcl-1 binding cavity using HTVS, SP, and XP docking modes of Glide. To assess their suitability as drug candidates, we conducted MM-GBSA calculations and ADME prediction, leading to the identification of 10 compounds with excellent binding affinity and favorable pharmacokinetic properties. To further investigate the interaction strength, we performed molecular dynamics simulations on the top three Mcl-1 receptor-ligand complexes to study their interaction stability. Overall, our findings suggest that these compounds have promising potential as anticancer agents, pending further experimental validation such as Mcl-1 apoptosis Assay. By combining experimental methods with various in silico approaches, these techniques prove to be invaluable for identifying novel drug candidates with distinct therapeutic applications using fragment-based drug design. This methodology has the potential to expedite the drug discovery process while also reducing its costs.
Présidence de la République : Arnold Munnich
Creators: name: Leibowitch, Jacques (1942-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: 1 fichier (1 page)