cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Process-as-a-Service Computing on Modern Serverless Platforms
Creators: name: Rethy, Gyorgy
Publisher: name: ETH Zurich
Year: 2022
Subjects: Cloud Computing
Serverless computing
Serverless Functions
Serverless Workflows
Distributed computing

description: Current serverless and FaaS offerings provide developers with a platform that frees them from the burden of infrastructure management while scaling automatically to demand. This made them increasingly popular, and as such there have been multiple initiatives to build cost-effective large-scale computational systems on top of it. Unfortunately, current platforms have severe limitations, especially around communication, that prevent these systems from achieving the expected results. Over the years, many solutions have been proposed and implemented. In this thesis, we look at such a new model, Process-as-a-Service (PraaS), and evaluate how it compares to the state of the art.
PraaS combines ephemeral functions with transient state and a data plane that allows for MPI-style, point-to-point messaging. We will explore how PraaS could be implemented on top of an existing container orchestration system and then combine it with a new serverless workflow executor.
In the end, we will see that workflows developed for this implementation can outperform even the most expensive current alternatives.
Additional file 4: Figure S2. of Gene expression and functional annotation of human choroid plexus epithelium failure in Alzheimerâ  s disease
Creators: name: Bergen, Arthur
name: Sovann Kaing
name: Brink, Jacoline Ten
name: Gorgels, Theo
name: Janssen, Sarah
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Upregulated genes in AD (Br5â  6). Molecular networks are presented which were generated by the core analysis of the Ingenuity knowledge database (see also Methods section and www.ingenuity.com for explanation and details). The symbols (with Genbank Gene name) in the network come from: input genes (Additional file 6: Table S3: upregulated genes in AD Br5â  6) see also description below (Additional file 5: Figure S3). (PDF 17491 kb)
title: Epigenetic regulation of ABCG2 promoter methylation in adolescents with hyperuricemia
Creators: name: Huang, Xueting
name: Xu, Chaojie
name: Li, Chen
name: Pan, Zhixian
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Hyperuricemia
subject: ABCG2
subject: Methylation
subject: CRISPR/dCas9-TET1
classificationCode: 570
subject: Biowissenschaften; Biologie

description: Background: Hyperuricemia is a metabolic disorder which is characterized by increased serum uric acid levels, which can contribute to serious health issues such as gout, cardiovascular disease, and kidney damage. Epigenetic modifications, for example, DNA methylation, exert a crucial function in gene regulation and have been implicated in various metabolic disorders. The ATP-Binding Cassette Subfamily G Member 2 (ABCG2) gene is involved in uric acid excretion, and its expression can be influenced by methylation of its promoter region. Methods: This study involved the design of three guide RNA (gRNA) sequences targeting specific CpG sites within the ABCG2 promoter region. Using the Clustered Regularly Interspaced Short Palindromic Repeats/dead Cas9-Ten-Eleven Translocation 1 (CRISPR/dCas9-TET1) system, these gRNAs were employed to guide targeted demethylation of the ABCG2 promoter in cell models. A non-targeting gRNA served as a negative control. The methylation status of the ABCG2 promoter and its effect on gene expression were assessed using bisulfite sequencing and qRT-PCR. Results: Among the gRNAs tested, gRNA2 and gRNA3 effectively guided the dCas9-TET1 complex to the ABCG2 promoter, resulting in significant demethylation. gRNA2 showed the most pronounced effect, leading to a substantial increase in ABCG2 expression. Clinical data analysis revealed that adolescents with hyperuricemia had higher uric acid levels compared to healthy controls, and a higher proportion of the hyperuricemia group reported a high-protein diet, suggesting a link between diet and ABCG2 methylation. Conclusion: The findings demonstrate that targeted demethylation of the ABCG2 promoter can significantly upregulate its expression, which may help modulate uric acid levels. These results indicate that dietary factors, such as a high-protein diet, could influence ABCG2 methylation and thus impact hyperuricemia. Advanced research is necessary to explore the therapeutic potential of aiming at epigenetic modifications for the treatment of hyperuricemia.
Concept Development for Hydrogen Methane Mixtures Combustion for Reduced Emissions
Creators: name: Eckard, Marcel
Publisher: name: ETH Zurich
Year: 2023
Subjects: CFD simulation
COMBUSTION CHAMBERS (GAS TURBINES)
Methane combustion
Hydrogen combustion
Model development

description: For more than 20 years, energy production has been experiencing a disruptive change to more efficient operation and fewer emissions. In 2018, heat production accounted for 50% of global final energy consumption and caused 40% of global carbon dioxide (CO₂) emissions. Around 50% of the total heat generated was consumed in industrial processes, while 46% was utilised in district heat for space and water heating. Combustion of natural gas provides a large share of this heat and will play a crucial role in decreasing emissions emitted by this sector. To reduce gas turbine generated CO₂ emissions, the replacement of fossil fuels is inevitable. A promising opportunity lies in the transition from hydrocarbon fuels to hydrogen (H₂). Not only does the combustion of H₂ emit no CO₂, carbon monoxide (CO) emissions are also avoided. Switching to H₂ and hydrogen natural gas fuel blends is accompanied by altered combustion characteristics, which need to be better understood. The goal of this thesis is to investigate the combustion behaviour of a newly developed multi-tube burner integrated in an existing can combustor. It is capable of burning hydrogen and natural gas mixtures. For this purpose, a simplified one-dimensional calculation model is developed to explore mass flows, pressure drops and velocities in the new system. The acquired data is subsequently used as input for a computational fluid dynamics model. Different modelling approaches are investigated to finally analyse the combustion behaviour of the system at base load with either H₂ or CH₄ as fuel. The simulations provide insights into parameter dependencies regarding flame front modelling. The computations highlight the feasibility of the technology concept for the chosen engine and that stable combustion is achievable. Furthermore, nitrogen oxides (NOₓ) emissions are analysed in post-processing calculations. These emphasise the importance of the thermal NOₓ generation path with flame temperatures close to 1800 K. Nonetheless, the threshold of 25 ppm is met for both fuels, with CH₄ combustion even reaching single-digit values. This project provides a modelling framework for a real-life test series of the current prototype burner combustor set-up. The conceptual basis helps to understand the expected combustion system behaviour as well as NOₓ emission levels.
Primus inter pares no more: Increasing the fault tolerance of wireless sensor networks
Creators: name: Kuonen, Tobias
Publisher: name: ETH Zurich
Year: 2021

description: Wireless sensor networks are prone to various types of failures, such as failing nodes, network partitions or lost messages. WSNs need methods for handling these failures for them to operate reliably. Popular techniques used by communication protocols for organizing themselves such as having a central leader might simplify coordination but also makes the communication more vulnerable to these failures. We therefore propose a new communication protocol designed to be resilient against node failures, network partitions and lost messages. All nodes are equal in the designed protocol, meaning that no node has any special role. We use a decentralized schedule update process to allow the nodes to dynamically reallocate resources. By leveraging common prior knowledge, we can generate a compatible communication schedule for every node despite incomplete information about the rest of the network. This allows the nodes to keep communicating even if the schedule update is impaired by failures. The nodes are also able to synchronize their clocks and to correct the drift of the local clock relative to the rest of the network without requiring a central reference clock. Using an implementation of our communication protocol running on a testbed, we show that across several network topologies, a data transmission is received by more than 97.5 % of all nodes on average. We also show that the nodes can to keep communicating reliably in the presence of artificially induces failures such as node failures or interference during the schedule update process.
MOESM1 of The impact of species and cell type on the nanosafety profile of iron oxide nanoparticles in neural cells
Creators: name: Joris, Freya
name: ValdepĂŠrez, Daniel
name: Pelaz, Beatriz
name: Soenen, Stefaan
name: Manshian, Bella
name: Parak, Wolfgang
name: Smedt, Stefaan De
name: Raemdonck, Koen
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer

description: Additional file 1. Full methodology on the synthesis and NP-cell interaction studies as well as and additional characterization data on the different NPs.
Additional file 17: Figure S7. of Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
Creators: name: Haeussler, Maximilian
name: Schönig, Kai
name: Eckert, Hélène
name: Eschstruth, Alexis
name: Mianné, Joffrey
name: Jean-Baptiste Renaud
name: Schneider-Maunoury, Sylvie
name: Shkumatava, Alena
name: Teboul, Lydia
name: Kent, Jim
name: Jean-Stephane Joly
name: Concordet, Jean-Paul
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Precision/recall for the top quartile against the top quartile of the predictions. Positives are the top 25 % of each assay. Precision is defined as the ratio True positives/(True positives + False positives) or intuitively the ability of a score not to label as positive a sample that is negative. The recall is the ratio True positives/(True positives + False negatives) or intuitively the ability of a score to find all the positive samples. When the cost of the assay is high and there are many candidate guide sequences, e.g., for a long exon in rats, the priority may be on precision or, conversely, it may be on recall for a short exon in Drosophila. Data are separated into three parts: (1) U6-base data, (2) T7 in vitro data, (3) data from this study. The rules by Ren and Farboud are already binary; all other scores were considered a positive if the rank-percent of the score exceeded 75 %. The 75 rank-percent cutoffs were: Housden, 6.8; Wang, 78; Chari, 53; Doench, 32; Moreno-Mateos, 60; Xu, 42; Fusi, 62; Wong, 0. The 75 % cutoff for the Wong score is indeed 0 as most values of this score are 0. The Wong score has a good precision on the large U6-based datasets but a relatively low recall. Among the heuristics, the -GG rule from Farboud et al. has high precision for T7 in vitro transcription datasets, except for the Farboud dataset where some guides have been designed to fulfill the rule, so it is not unbiased. In U6-based datasets, most scores show a similar precision, but the Fusi et al. score has generally higher recall. (PDF 147 kb)
Additional file 9: Figure S4. of Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
Creators: name: Haeussler, Maximilian
name: Schönig, Kai
name: Eckert, Hélène
name: Eschstruth, Alexis
name: Mianné, Joffrey
name: Jean-Baptiste Renaud
name: Schneider-Maunoury, Sylvie
name: Shkumatava, Alena
name: Teboul, Lydia
name: Kent, Jim
name: Jean-Stephane Joly
name: Concordet, Jean-Paul
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Similar to Fig. 3 but using off-target predictions by the CRISPR Design website ( http://crispr.mit.edu/ ). a For the 28 tested guide sequences, MIT guide specificity scores as calculated by the MIT website (x-axis), number of off-targets (y-axis), and sum of off-target modification frequencies (circle size). b The specificity of the 28 tested guide sequences (blue) versus the specificity scores of all unique 20mers in human coding regions (green). The specificity score histogram was calculated by running 1000 randomly selected guide sequences from human coding regions through the CRISPR Design website ( http://crispr.mit.edu/ ). (PDF 40 kb)
Additional file 1: of Effectiveness, immunogenicity and safety of 23-valent pneumococcal polysaccharide vaccine revaccinations in the elderly: a systematic review
Creators: name: Remschmidt, Cornelius
name: Harder, Thomas
name: Wichmann, Ole
name: Bogdan, Christian
name: Falkenhorst, Gerhard
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Search strategy for the manuscript entitled â  Effectiveness, immunogenicity and safety of 23-valent pneumococcal polysaccharide vaccine revaccinations in the elderly: a systematic reviewâ  . List of excluded studies (full-texts) on effectiveness, immunogenicity and safety of 23-valent pneumococcal polysaccharide vaccine revaccinations in the elderly. Ratios (2nd dose PPSV23/1st dose PPSV23) of geometric mean concentrations (GMC) of pneumococcal serotypes. Ratios (2nd dose PPSV23/1st dose PPSV23) of opsonophagocytic assays (OPA). (DOCX 816 kb)
Leptocheliidae Lang 1973
Creators: name: Morales-Núñez, Andrés G.
name: Heard, Richard W.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Tanaidacea
Leptocheliidae

description: Family Leptocheliidae Lang, 1973
Subfamily Leptocheliinae Lang, 1973
description: Published as part of Morales-Núñez, Andrés G. & Heard, Richard W., 2015, Cacoheterotanais rogerbamberi, a new genus and species of leptocheliid Tanaidacea (Crustacea: Peracarida) from shelf-waters of the Gulf of Mexico, pp. 169-188 in Zootaxa 3995 (1) on page 170, DOI: 10.11646/zootaxa.3995.1.16, http://zenodo.org/record/235985
Additional file 1: Figure S1. of Change in trade wind inversion frequency implicated in the decline of an alpine plant
Creators: name: Krushelnycky, Paul
name: Starr, Forest
name: Starr, Kim
name: Longman, Ryan
name: Frazier, Abby
name: Loope, Lloyd
name: Giambelluca, Thomas
Publisher: name: Figshare
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Map of the top of Haleakala volcano, showing census counting areas. Red polygons indicate 111 count sectors, black polygons indicate the 19 larger regions that were surveyed in all five censuses. (PDF 371Â kb)
Additional file 1: of The Medical Professionalism of Korean Physicians: Present and Future
Creators: name: Soojung Kim
name: Sookhee Choi
Publisher: name: Figshare
Year: 2015
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Choiâ  s Questionnaire. (DOCX 14 kb)
Additional file 1: of PSE-HMM: genome-wide CNV detection from NGS data using an HMM with Position-Specific Emission probabilities
Creators: name: Malekpour, Seyed
name: Pezeshk, Hamid
name: Sadeghi, Mehdi
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Section S.2 of this additional file provides a detailed description for the parameter estimation in PSE-HMM. In section S.3, the effect of segment size on the performance of the PSE-HMM is investigated. In section S.4, sensitivity of the prediction accuracies to the genome-wide CNV percentage is analyzed. Section S.5 describes the overlap of PSE-HMMâ  s deletion calls against CNVs which are detected in [30]. Moreover, robustness of PSE-HMM to deviations from the assumption of normality in the insertion size distribution is investigated in section S.6. (DOCX 296Â kb)
Additional file 1: of Productive and reproductive performances of dairy cattle herds in Treviso province, Italy (2009â  2012): an assessment of the potential impact of Schmallenberg virus epidemic
Creators: name: Toson, Marica
name: Mughini-Gras, Lapo
name: Capello, Katia
name: Gagliazzo, Laura
name: Bortolotti, Laura
name: Mazzucato, Matteo
name: Marangon, Stefano
name: Lebana Bonfanti
Publisher: name: Figshare
Year: 2015
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Correlation matrix of the continuous productive and reproductive performance indicators of dairy cattle herds. (DOCX 18 kb)
Gahrliepia (Gateria) crocidura Radford 1946
Creators: name: Nielsen, David H.
name: Robbins, Richard G.
name: Rueda, Leopoldo M.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Trombiculidae
Gahrliepia
Gahrliepia crocidura

description: Gahrliepia (Gateria) crocidura Radford, 1946 a:
ORI
Gateria crocidura, Gunther 1952
Gahrliepia (Gahrliepia) crocidura, Traub & Morrow 1955; Audy 1956c; Traub & Morrow 1955
Gahrliepia (Gateria) crocidura, Womersley 1952; Vercammen-Grandjean 1968c
Gahrliepia crocidura, Prasad 1974; Fernandes & Kulkarni 2003
Gateria (Gateria) crocidura, Wen & Gui 2000
Syn.: Gateria lancearia Radford, 1946 a
Gahrliepia (Gateria) lancearia, Womersley 1952
Gateria lancearia, Gunther 1952
description: Published as part of Nielsen, David H., Robbins, Richard G. & Rueda, Leopoldo M., 2021, Annotated world checklist of the Trombiculidae and Leeuwenhoekiidae (1758 - 2021) (Acari: Trombiculoidea), with notes on nomenclature, taxonomy, and distribution, pp. 1-243 in Zootaxa 4967 (1) on page 25, DOI: 10.11646/zootaxa.4967.1.1, http://zenodo.org/record/4745510
Additional file 1: of An heuristic filtering tool to identify phenotype-associated genetic variants applied to human intellectual disability and canine coat colors
Creators: name: Broeckx, Bart
name: Coopman, Frank
name: Verhoeven, Geert
name: Bosmans, Tim
name: Gielen, Ingrid
name: Dingemanse, Walter
name: Saunders, Jimmy
name: Deforce, Dieter
name: Nieuwerburgh, Filip Van
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Command line used for example 1 and 2. The commands used in example 1 and example 2 are depicted in this additional file, together with a brief explanation. (PDF 178Â kb)
Additional file 1: of Genomic prediction using imputed whole-genome sequence data in Holstein Friesian cattle
Creators: name: Binsbergen, Rianne Van
name: Calus, Mario
name: Bink, Marco
name: Eeuwijk, Fred
name: Schrooten, Chris
name: Veerkamp, Roel
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Marine Biology

description: Conditional posterior densities BSSVS model. This file describes the conditional posterior densities for the BSSVS model. (PDF 82Â kb)
Additional file 2: Figure S1. of Genomic prediction using imputed whole-genome sequence data in Holstein Friesian cattle
Creators: name: Binsbergen, Rianne Van
name: Calus, Mario
name: Bink, Marco
name: Eeuwijk, Fred
name: Schrooten, Chris
name: Veerkamp, Roel
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: 60506 Virology

description: SNP variance components across cycles for the BSSVS model. Values are shown for somatic cell score (SCS), interval between first and last insemination (IFL), and protein yield (PY) for the three replicates using BovineHD data and imputed sequence data. Figure S2. Original versus predicted breeding values for somatic cell score for the two methods (GBLUP and BSSVS) using the three types of data (BovineHD, ImputedHD, and imputed sequence) for the 2087 validation animals. Figure S3. Original versus predicted breeding values for interval between first and last insemination for the two methods (GBLUP and BSSVS) using the three types of data (BovineHD, ImputedHD, and imputed sequence) for the 2087 validation animals. Figure S4. Original versus predicted breeding values for protein yield for the two methods (GBLUP and BSSVS) using the three types of data (BovineHD, ImputedHD, and imputed sequence) for the 2087 validation animals. (PDF 529Â kb)
Additional file 3: Table S1. of Genomic prediction using imputed whole-genome sequence data in Holstein Friesian cattle
Creators: name: Binsbergen, Rianne Van
name: Calus, Mario
name: Bink, Marco
name: Eeuwijk, Fred
name: Schrooten, Chris
name: Veerkamp, Roel
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Correlations between predictions of the different models. Table S2. Estimates of genetic parameters for GBLUP model including polygenic component for somatic cell score. (PDF 45Â kb)
MA'LUMOTLAR BAZASINI LOYIHALASH. ER MODELLAR. RELYATSION MODEL.
Creators: name: Tojimamatov, Israiljon
name: Meliboyeva, Azimaxon
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqola ma’lumotlar bazasini loyihalash bosqichlarini, ER modellar va relyatsion model haqida bir qancha tushunchalarni o‘rganilgan.
Additional file 1: of Challenges and opportunities associated with the introduction of next-generation long-lasting insecticidal nets for malaria control: a case study from Burkina Faso
Creators: name: Kemi Tesfazghi
name: Traore, Adama
name: Ranson, Hilary
name: Sagnon NâFale
name: Hill, Jenny
name: Worrall, Eve
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Semi-structured interview guide. (DOCX 22 kb)
Additional file 2: of Challenges and opportunities associated with the introduction of next-generation long-lasting insecticidal nets for malaria control: a case study from Burkina Faso
Creators: name: Kemi Tesfazghi
name: Traore, Adama
name: Ranson, Hilary
name: Sagnon NâFale
name: Hill, Jenny
name: Worrall, Eve
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Ethics Approval Burkina Faso. (DOCX 1312 kb)
Additional file 3: of Challenges and opportunities associated with the introduction of next-generation long-lasting insecticidal nets for malaria control: a case study from Burkina Faso
Creators: name: Kemi Tesfazghi
name: Traore, Adama
name: Ranson, Hilary
name: Sagnon NâFale
name: Hill, Jenny
name: Worrall, Eve
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Quotes. (DOCX 115 kb)
Die Triebkräfte des Wandels und der Grad der Policy-Integration des Gewässermanagements im Gebiet Alpthal – eine Fallstudie
Creators: name: Pettersson, Fredrik
name: Steinegger, Ladina
Publisher: name: ETH Zurich
Year: 2022

description: Die Gewässer der Schweiz sind Gegenstand etlicher Interessen, wie etwa des Hochwasserschutzes, der Trinkwasserversorgung, der Energieproduktion oder aber des Naturschutzes. Für eine nachhaltige Bewirtschaftung dieser Wasserkörper ist es unabdingbar, die verschiedenen geäusserten Interessen aufeinander abzustimmen. Um die Triebkräfte zu verstehen, welche das Gewässermanagement prägen, und den Grad der Policy-Integration zu bestimmen, welcher Aufschluss darüber geben soll, wie gut die Wasserwirtschaftsinteressen aufeinander abgestimmt sind, führen wir eine Fallstudie im Alptal im Kanton Schwyz durch. Anhand einer historischen Analyse von Archivdokumenten über das Gewässermanagement im Alptal und einer Policy-Integrationsanalyse der Gesetzestexte im Kanton Schwyz der Jahre 1848-2021 beantworten wir folgende Forschungsfrage: 

Was sind die Triebkräfte im Alptal, die dazu führten, dass die Alp und ihre Zuflüsse so bewirtschaftet werden wie heute und wie integriert sind die drei Interessen der Wasserwirtschaft „Wasser nutzen“, „Schutz vor Wasser“ und „Schutz des Wassers“? 

Wir stellen fest, dass der Grad der Policy-Integration im Kanton Schwyz über die Zeit so weit zugenommen hat, dass man von einer integrierten Wasserwirtschaft sprechen kann. Diese berücksichtigt die Interessen «Wasser nutzen», «Schutz vor Wasser» und «Schutz des Wassers» und versucht sie aufeinander abzustimmen. Die Triebkräfte des Gewässermanagements im Alptal haben sich über die Zeit verändert. Bestimmten früher vorwiegend lokale Triebkräfte wie Naturereignisse den Umgang mit den Gewässern, so nahm der Einfluss von Vorgaben seitens Kanton und Bund immer mehr zu. Dadurch nimmt die integrierte Wasserwirtschaft des Kantons inzwischen so weit Einfluss auf das Alptal, dass bestehende Strukturen wie die der Wuhrkorporation Alp nicht mehr zeitgenössisch sind. Somit findet innerhalb der Integration des einen Systems (Gewässermanagement Kanton Schwyz) eine Desintegration eines anderen Systems (Gewässermanagement Alptal) statt. Diese Desintegration kann mit dem Verlust von Bewirtschaftungselementen verbunden sein, welche sich über eine lange Zeit bewährt haben. Deshalb ist es essentiell, sich dieser Entwicklung bewusst zu werden und die Elemente zu identifizieren und beizubehalten, welche ein erfolgreiches und nachhaltiges Gewässermanagement der Zukunft erlauben.
Additional file 6: Table S2. of ZNStress: a high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosis
Creators: name: McGown, Alexander
name: Dame Shaw
name: Tennore Ramesh
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Effects of drugs tested in human ALS in the mutant sod1 ZNSstress assay. (DOC 43 kb)
Existence of SRB measures in chaotic random motions: a graph transform approach
Creators: name: Gerber, Damian
Publisher: name: ETH Zurich
Year: 2022
Subjects: subject: info:eu-repo/classification/ddc/510
subject: Mathematics
subject: FOS: Mathematics

description: SRB measures present a useful class of invariant measures that help understand the chaotic nature of random dynamical systems. Inspired by a paper from Alex Blumenthal and Lai-Sang Young from 2018 titled ”Equivalence of physical and SRB measures in random dynamical systems” this BSc project discusses the existence of SRB measures in chaotic random motions. We look at an innovative geometric construction of SRB measures via a graph transform approach that uses adapted one- sided charts. By pushing forward the stationary measures and approximating the unstable manifolds with pushed forward leaves we show that the sample measures are SRB.
Additional file 2: Table S1. of ZNStress: a high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosis
Creators: name: McGown, Alexander
name: Dame Shaw
name: Tennore Ramesh
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Table of SSMD Î˛-value hit selection criteria. (DOC 32 kb)
Additional file 7: Table S5. of Intra- and interspecies gene expression models for predicting drug response in canine osteosarcoma
Creators: name: Fowles, Jared
name: Brown, Kristen
name: Hess, Ann
name: Duval, Dawn
name: Gustafson, Daniel
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Factors associated with disease free interval of COS33 patients in a univariate analysis. (DOCX 15Â kb)
Additional file 1: Table S1. of Intra- and interspecies gene expression models for predicting drug response in canine osteosarcoma
Creators: name: Fowles, Jared
name: Brown, Kristen
name: Hess, Ann
name: Duval, Dawn
name: Gustafson, Daniel
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: FACC panel info. (DOCX 17Â kb)
Gahrliepia (Gateria) darita Traub and Morrow 1955
Creators: name: Nielsen, David H.
name: Robbins, Richard G.
name: Rueda, Leopoldo M.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Trombiculidae
Gahrliepia
Gahrliepia darita

description: Gahrliepia (Gateria) darita Traub and Morrow, 1955:
ORI
Gahrliepia (Gahrliepia) darita Traub and Morrow, 1955
Gahrliepia (Gateria) darita, Vercammen-Grandjean 1968c
Gateria (Gateria) darita, Wen & Gui 2000
Gahrliepia darita, Fernandes & Kulkarni 2003; Stekolnikov 2021
description: Published as part of Nielsen, David H., Robbins, Richard G. & Rueda, Leopoldo M., 2021, Annotated world checklist of the Trombiculidae and Leeuwenhoekiidae (1758 - 2021) (Acari: Trombiculoidea), with notes on nomenclature, taxonomy, and distribution, pp. 1-243 in Zootaxa 4967 (1) on page 25, DOI: 10.11646/zootaxa.4967.1.1, http://zenodo.org/record/4745510
E-Bikes’ Effect on Mode and Route Choice: A Case Study of Richmond, VA Bike Share
Creators: name: Chavis, Celeste
name: Frias-Martinez, Vanessa
Publisher: name: Maryland Shared Open Access Repository
Year: 2021
Subjects: e-bike, route choice, bike share

description: The bicycle has become a legitimate transportation option in many cities due to its different benefits. Lower transportation costs, health improvement, and lower emission rates are some critical benefits of a bicycle ride. A large body of research exists on bicycle route choice and travel behavior. There is currently a lack of research on mode shift and route choice changes with the introduction of e-bikes. This study has presented a comprehensive analysis of the similarities and differences between a pedelec and regular bicycle use in Richmond City, Virginia, as well as an evaluation of how membership type and other user characteristics might influence bike share use. This study utilized GPS data for a docked bike-share system in Richmond, Virginia, from March 2019, when RVA Bike Share began converting the traditional bikes to e-bikes. To retrieve the data this study used Mapbox's Map Matching API, which snaps fuzzy, inaccurate GPS traces to actual segments in the road network, breaks the snapped roads into segments and queries each segment in Open Street Maps (OSM) to identify the type of road. This study did a comprehensive descriptive analysis, origin-destination trip analysis, and user cluster analysis with the retrieved data. The results have shown that pedelecs are generally associated with longer trip distances, shorter trip times, higher speeds and lower elevations. In April, about 25% of the fleet was pedelec bikes and by December, approximately 65%. The t-tests results showed that the mean number of trips made per bike available was significantly more (~3.2x) for pedelecs compared to bikes (p-value=0.004). The origin-destination analysis considered the business, mixed use, residential and other uses and observed that the plots show extremely similar trends with a large number of trips staying within either business or residential locations or mixed use. The roadway use analysis and mapping showed that pedelecs were used farther outside of the city than bikes. Additionally, pedelecs were frequently used in the downtown core where most RVA bike share stations are located. In terms of memberships, longer-term memberships (annual, monthly) were found to be associated with significantly higher use of pedelecs than shorter-term memberships, potentially pointing to a lack of knowledge on the part of those who use the system less frequently or to a preference for normal bicycles. Finally, the user cluster analysis identified six diverse types of behaviors that varied by geographical region (e.g., central Richmond vs. recreational areas), as well as by trip distance, trip duration, and bike type.
How Mobility and Accessibility Affect Crime Rates: Insights from Mobile Device Location Data
Creators: name: Zhang, Lei
name: Yang, Mofeng
name: Zhao, Guangchen
name: Darzi, Aref
name: Ghader, Sepehr
Publisher: name: Maryland Shared Open Access Repository
Year: 2021
Subjects: Mobile Device Location Data; Mobility; Accessibility; High-Crime Neighborhoods

description: This research study investigates the possible correlations between mobility, accessibility, and crime rate. A rich mobile device location dataset including detailed anonymized location traces of the mobile devices observed in the City of Baltimore was combined with the police arrest records to study how mobility and accessibility affect neighborhood safety. The research team first processed and analyzed the mobile device location dataset to obtain measures of mobility and accessibility. These measures differed from the traditional measures in that they were obtained based on the empirically observed location data. The research team then built statistical and machine learning tools to model crime rates at the census-tract levels, using the calculated mobility and accessibility measures, land-use variables, and socioeconomic-related variables as the covariates. Subsequently, the team focused on the correlation of the crime rates with the mobility and accessibility variables. Results indicated that the mobility and accessibility measures can help improve the performance of crime rate prediction. Also, non-motorized travel might be positively related to burglary. The study seeks to inform decision-makers about the transportation-related issues contributing to the lack of safety and offer transportation solutions to crime-related problems, especially in the neighborhoods suffering from high crime rates.
Additional file 19: Figure S9. of Global expression differences and tissue specific expression differences in rice evolution result in two contrasting types of differentially expressed genes
Creators: name: Horiuchi, Youko
name: Harushima, Yoshiaki
name: Fujisawa, Hironori
name: Mochizuki, Takako
name: Fujita, Masahiro
name: Ohyanagi, Hajime
name: Kurata, Nori
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Expression types of global DE genes among the three strains. (PDF 344Â kb) (PDF 333Â kb)
Additional file 21: Figure S10. of Global expression differences and tissue specific expression differences in rice evolution result in two contrasting types of differentially expressed genes
Creators: name: Horiuchi, Youko
name: Harushima, Yoshiaki
name: Fujisawa, Hironori
name: Mochizuki, Takako
name: Fujita, Masahiro
name: Ohyanagi, Hajime
name: Kurata, Nori
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Commonly detected changed-tissues jiDE genes between the NM and NZ combinations. (PDF 385Â kb) (PDF 372Â kb)
Evaluation of Xilinx Versal Device
Creators: name: Wierse, Max
Publisher: name: ETH Zurich
Year: 2023

description: The ”Adaptive Compute Acceleration Platform” from AMD/Xilinx combines a classical FPGA part with a CGRA part, the so-called AI Engines, to open up new ways to increase the performance of powerful computers.
While ACAP based devices are now available for end users, it is still unclear what the actual capabilities of these devices are and how to use them most effectively. As the first step of this thesis, we examined the provided API and toolchain. We identified two mechanisms that are crucial for the performance of parallel applications. First, the communication between the AI Engines and the off-chip memory, and second the direct inter AI Engine communication. To perform various scientific benchmarks of the off-chip memory and the inter AI Engine communication the VCK190 Evaluation Kit from AMD/Xilinx was used. One part of the benchmarks focussed on the throughput of the communication between the AI Engines and the off-chip memory. The other part benchmarked the throughput of the inter AI Engine communication.
From the results, it is evident that the behaviour of the benchmarked communication mostly matches the manufacturer’s specifications. Nevertheless, there are unexplainable behaviour patterns that need further investigation.
The outlook shows that it might be interesting to benchmark the latencies of these communication methods in addition to the throughputs. Furthermore, it could be interesting to implement some additional communication APIs to improve the programmability of these AI Engines.
Additional file 11: Figure S7. of Global expression differences and tissue specific expression differences in rice evolution result in two contrasting types of differentially expressed genes
Creators: name: Horiuchi, Youko
name: Harushima, Yoshiaki
name: Fujisawa, Hironori
name: Mochizuki, Takako
name: Fujita, Masahiro
name: Ohyanagi, Hajime
name: Kurata, Nori
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Ratio distribution of changed-tissues jiDE genes of the NM combination. (PDF 762Â kb) (PDF 741Â kb)
Equity in Accessibility to Opportunities: Insights, Measures, and Solutions based on Mobile Device Location Data
Creators: name: Zhang, Lei
name: Shin, Hyeon-Shic
name: Ghader, Sepehr
name: Darzi, Aref
name: Zhao, Guangchen
name: Kabiri, Aliakbar
Publisher: name: Maryland Shared Open Access Repository
Year: 2021
Subjects: Mobile device location data, accessibility data analysis, travel patterns, equity, work trips

description: This report summarizes the study of accessibility to opportunities among different population groups and neighborhoods in Baltimore City. The study is the first of its kind in utilizing observed multimodal mobile device location data from individual devices to systematically study accessibility to opportunities. Passively collected mobile device location data used in this study reveal day-to-day travel patterns of more than 25% of the U.S. population for an entire year across the nation. To showcase the application of this data, we selected the Baltimore city as our testbed. This new data source with very high sampling rates, combined with point of interest data and census data, allows us to analyze how residents in each neighborhood travel to work or seek their essential needs such as food and healthcare. The study introduces a data-driven accessibility measure based on the observed location data, which can also be calculated using individual-level outputs of a typical activity-based model. Research findings directly identify accessibility gaps among neighborhoods. In addition to the above, accessibility and equity measures from mobile device location data are compared with traditional measures, and the comparison results are discussed. Furthermore, this study draws on information from the data-driven method to capture the differences in accessibility among different income groups.
Additional file 1: Figure S1. of Global expression differences and tissue specific expression differences in rice evolution result in two contrasting types of differentially expressed genes
Creators: name: Horiuchi, Youko
name: Harushima, Yoshiaki
name: Fujisawa, Hironori
name: Mochizuki, Takako
name: Fujita, Masahiro
name: Ohyanagi, Hajime
name: Kurata, Nori
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Probe Selection by using SNEP two-sided test. (PDF 313Â kb) (PDF 301Â kb)
How Mobility and Accessibility Affect Crime Rates: Insights from Mobile Device Location Data
Creators: name: Zhang, Lee
name: Yang, Mofeng
name: Zhao, Guangchen
name: Darzi, Aref
name: Ghader, Sepehr
Publisher: name: Maryland Shared Open Access Repository
Year: 2021
Subjects: Mobile Device Location Data; Mobility; Accessibility; High-Crime Neighborhoods

description: This research study investigates the possible correlations between mobility, accessibility, and crime rate. A rich mobile device location dataset including detailed anonymized location traces of the mobile devices observed in the City of Baltimore was combined with the police arrest records to study how mobility and accessibility affect neighborhood safety. The research team first processed and analyzed the mobile device location dataset to obtain measures of mobility and accessibility. These measures differed from the traditional measures in that they were obtained based on the empirically observed location data. The research team then built statistical and machine learning tools to model crime rates at the census-tract levels, using the calculated mobility and accessibility measures, land-use variables, and socioeconomic-related variables as the covariates. Subsequently, the team focused on the correlation of the crime rates with the mobility and accessibility variables. Results indicated that the mobility and accessibility measures can help improve the performance of crime rate prediction. Also, non-motorized travel might be positively related to burglary. The study seeks to inform decision-makers about the transportation-related issues contributing to the lack of safety and offer transportation solutions to crime-related problems, especially in the neighborhoods suffering from high crime rates.
Additional file 26: Table S15. of Global expression differences and tissue specific expression differences in rice evolution result in two contrasting types of differentially expressed genes
Creators: name: Horiuchi, Youko
name: Harushima, Yoshiaki
name: Fujisawa, Hironori
name: Mochizuki, Takako
name: Fujita, Masahiro
name: Ohyanagi, Hajime
name: Kurata, Nori
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Description of the number of unique transcripts and unique probes. (DOCX 111Â kb) (DOCX 105Â kb)