Additional file 1 of Associations of sugar intake, high-sugar dietary pattern, and the risk of dementia: a prospective cohort study of 210,832 participants
Creators: name: Zhang, Sirui
name: Xiao, Yi
name: Cheng, Yangfan
name: Ma, Yuanzheng
name: Liu, Jiyong
name: Li, Chunyu
name: Shang, Huifang
Publisher: name: figshare
Year: 2024
Subjects: subject: Neuroscience
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Mental Health

description: Additional file 1: Table S1-Food groups and their contents. Table S2-UK Biobank codes for dementia diagnosis and classification. Table S3-The variates used in the present study from the UK Biobank. Table S4-Information of missing covariates in model 3. Table S5-Factor loadings for high-sugar dietary pattern among participants completing one dietary assessment. Table S6-Mean sugars intake by quartile of high-sugar dietary pattern score. Table S7-Associations between sugar intake, high-sugar dietary score and all-cause dementia in three models. Table S8-Associations between sugar intake, high-sugar dietary score and Alzheimer’s disease in three models. Table S9-Associations between subtypes of sugars and all-cause dementia in three models. Table S10-Associations between subtypes of sugars and Alzheimer’s disease in three models. Table S11-Inflection points where HR = 1 in the RCS analyses. Table S12-P values on the interaction between exposures and stratification variables with all-cause dementia incidents. Table S13-P values on the interaction between exposures and stratification variables with Alzheimer’s disease incidents. Table S14-Age-specific subgroup analyses of associations between sugar intake, high-sugar dietary score and all-cause dementia. Table S15-Sex-specific subgroup analyses of associations between sugar intake, high-sugar dietary score and all-cause dementia. Table S16-APOE-specific subgroup analyses of associations between sugar intake, high-sugar dietary score and all-cause dementia. Table S17-Age-specific subgroup analyses of associations between sugar intake, high-sugar dietary score and Alzheimer’s disease. Table S18-Sex-specific subgroup analyses of associations between sugar intake, high-sugar dietary score and Alzheimer’s disease. Table S19-Mediation analyses of absolute total sugar intake and dementia. Table S20-Mediation analyses of relative total sugar intake and dementia. Table S21-Sensitivity analysis excluding participants developing all-cause dementia within 3 years. Table S22-Factor loadings for high-sugar dietary pattern among participants who completed at least two dietary assessments. Table S23-Factor loadings for high-sugar dietary pattern among participants who completed at least three dietary assessments. Table S24-Factor loadings for high-sugar dietary pattern among participants who completed at least four dietary assessments. Table S25-Sensitivity analysis among participants who completed at least two dietary assessments. Table S26-Sensitivity analysis among participants who completed at least three dietary assessments. Table S27-Sensitivity analysis among participants who completed at least four dietary assessments.