cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Highly sensitive sandwich immunoassay and immunochromatographic test for the detection of Clostridial epsilon toxin in complex matrices
Creators: name: Féraudet-Tarisse, Cécile
name: Mazuet, Christelle
name: Pauillac, Serge
name: Krüger, Maren
name: Lacroux, Caroline
name: Popoff, Michel R.
name: Dorner, Brigitte
name: Andréoletti, Olivier
name: Plaisance, Marc
name: Volland, Hervé
name: Simon, Stéphanie
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2017
Subjects: subject: 610 Medizin

description: Epsilon toxin is one of the four major toxins of Clostridium perfringens. It is the third most potent clostridial toxin after botulinum and tetanus toxins and is thus considered as a potential biological weapon classified as category B by the Centers for Disease Control and Prevention (CDC). In the case of a bioterrorist attack, there will be a need for a rapid, sensitive and specific detection method to monitor food and water contamination by this toxin, and for a simple human diagnostic test. We have produced and characterized five monoclonal antibodies against common epitopes of epsilon toxin and prototoxin. Three of them neutralize the cytotoxic effects of epsilon toxin in vitro. With these antibodies, we have developed highly sensitive tests, overnight and 4-h sandwich enzyme immunoassays and an immunochromatographic test performed in 20 min, reaching detection limits of at least 5 pg/mL (0.15 pM), 30 pg/mL (0.9 pM) and 100 pg/mL (3.5 pM) in buffer, respectively. These tests were also evaluated for detection of epsilon toxin in different matrices: milk and tap water for biological threat detection, serum, stool and intestinal content for human or veterinary diagnostic purposes. Detection limits in these complex matrices were at least 5-fold better than those described in the literature (around 1 to 5 ng/mL), reaching 10 to 300 pg/mL using the enzyme immunoassay and 100 to 2000 pg/mL using the immunochromatographic test.
Supplemental Material, sj-pdf-1-jcr-10.1177_00220027211025597 - Revisiting Opportunism in Civil Conflict: Natural Resource Extraction and Health Care Provision
Creators: name: Conrad, Justin
name: Reyes, Liana Eustacia
name: Stewart, Megan A.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 220104 Human Rights and Justice Issues
subject: FOS: Philosophy, ethics and religion
subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material, sj-pdf-1-jcr-10.1177_00220027211025597 for Revisiting Opportunism in Civil Conflict: Natural Resource Extraction and Health Care Provision by Justin Conrad, Liana Eustacia Reyes and Megan A. Stewart in Journal of Conflict Resolution
The association between nutritional-inflammatory status and chronic kidney disease prognosis: a population-based study
Creators: name: Zhang, Xinyu
name: Hu, Xuanhan
name: Qian, Lin
name: Chen, Zeqi
name: Hua, Xintao
name: Zhang, Dahong
name: Wei, Haibin
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Chronic kidney disease (CKD) prognosis is closely tied to the interplay between nutrition and inflammation. However, comprehensive nutritional-inflammatory indices for prognostic evaluation are rare in CKD. This study explored the association of the advanced lung cancer inflammation index (ALI) with estimated glomerular filtration rate (eGFR) and all-cause mortality in CKD patients. A total of 1,982 CKD patients from the National Health and Nutrition Examination Survey (NHANES) database (2011–2018) were included in the analysis. Analytical methods included linear regression, cox regression, and restricted cubic spline (RCS) analysis. Subgroup and sensitivity analyses were performed, and further evaluation was conducted using the receiver operating characteristic (ROC) curve and C-index for all-cause mortality across different CKD stages. Among CKD patients, 1,103 patients (55.7%) were classified as stage I–II, and 879 patients (44.3%) as stage III–V. After adjusting covariates, ALI was found to be positively correlated with eGFR (Beta = 0.11; 95% CI: 0.07–0.15), and negatively related with all-cause mortality (HR = 0.72; 95% CI: 0.63–0.83). Subgroup analysis showed that the positive correlation between ALI and eGFR was stronger in CKD stage III–V compared to stage I–II. However, ALI’s protective effect on mortality was weaker in stage III–V. The C-index for ALI was 0.648 in stage I–II and 0.660 in stage III–V. ALI was significantly associated with eGFR and all-cause mortality in CKD patients. Nutritional and anti-inflammatory interventions in early-stage CKD may improve prognosis, and ALI may have great potential as a multifaceted biomarker to influence the prognosis of CKD, particularly in stages III–V.
Additional file 1 of Validity and reliability of the Greek version of Wijma delivery expectancy/experience questionnaire (Version A) among low-risk pregnant women
Creators: name: Varela, Pinelopi
name: Zervas, Ioannis
name: Vivilaki, Victoria
name: Lykeridou, Aikaterini
name: Deltsidou, Anna
Publisher: name: figshare
Year: 2024
Subjects: Cell Biology
Biotechnology
Developmental Biology
Science Policy
Mental Health

description: Supplementary Material 1
Comparative Genomics of Escherichia coli Isolated from Skin and Soft Tissue and Other Extraintestinal Infections
Creators: name: Ranjan, Amit
name: Shaik, Sabiha
name: Nandanwar, Nishant
name: Hussain, Arif
name: Tiwari, Sumeet K.
name: Semmler, Torsten
name: Jadhav, Savita
name: Wieler, Lothar H.
name: Alam, Munirul
name: Colwell, Rita R.
name: Ahmed, Niyaz
Publisher: name: Robert Koch-Institut
Year: 2017
Subjects: subject: 610 Medizin

description: Escherichia coli, an intestinal Gram-negative bacterium, has been shown to be associated with a variety of diseases in addition to intestinal infections, such as urinary tract infections (UTIs), meningitis in neonates, septicemia, skin and soft tissue infections (SSTIs), and colisepticemia. Thus, for nonintestinal infections, it is categorized as extraintestinal pathogenic E. coli (ExPEC). It is also an opportunistic pathogen, causing cross infections, notably as an agent of zoonotic diseases. However, comparative genomic data providing functional and genetic coordinates for ExPEC strains associated with these different types of infections have not proven conclusive. In the study reported here, ExPEC E. coli isolated from SSTIs was characterized, including virulence and drug resistance profiles, and compared with isolates from patients suffering either pyelonephritis or septicemia. Results revealed that the majority of the isolates belonged to two pathogenic phylogroups, B2 and D. Approximately 67% of the isolates were multidrug resistant (MDR), with 85% producing extended-spectrum beta-lactamase (ESBL) and 6% producing metallo-beta-lactamase (MBL). The blaCTX-M-15 genotype was observed in at least 70% of the E. coli isolates in each category, conferring resistance to an extended range of beta-lactam antibiotics. Whole-genome sequencing and comparative genomics of the ExPEC isolates revealed that two of the four isolates from SSTIs, NA633 and NA643, belong to pandemic sequence type ST131, whereas functional characteristics of three of the ExPEC pathotypes revealed that they had equal capabilities to form biofilm and were resistant to human serum. Overall, the isolates from a variety of ExPEC infections demonstrated similar resistomes and virulomes and did not display any disease-specific functional or genetic coordinates.
Large measles outbreak introduced by asylum seekers and spread among the insufficiently vaccinated resident population, Berlin, October 2014 to August 2015
Creators: name: Werber, Dirk
name: Hoffmann, Alexandra
name: Santibanez, Sabine
name: Mankertz, Annette
name: Sagebiel, Daniel
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger; Robert Koch-Institut, Infektionsepidemiologie
Year: 2017
Subjects: subject: 610 Medizin

description: The largest measles outbreak in Berlin since 2001 occurred from October 2014 to August 2015. Overall, 1,344 cases were ascertained, 86% (with available information) unvaccinated, including 146 (12%) asylum seekers. Median age was 17 years (interquartile range: 4–29 years), 26% were hospitalised and a 1-year-old child died. Measles virus genotyping uniformly revealed the variant ‘D8-Rostov-Don’ and descendants. The virus was likely introduced by and initially spread among asylum seekers before affecting Berlin’s resident population. Among Berlin residents, the highest incidence was in children aged
PRECEPT: an evidence assessment framework for infectious disease epidemiology, prevention and control
Creators: name: Harder, Thomas
name: Takla, Anja
name: Eckmanns, Tim
name: Ellis, Simon
name: Forland, Frode
name: James, Roberta
name: Meerpohl, Joerg J.
name: Morgan, Antony
name: Rehfuess, Eva
name: Schünemann, Holger
name: Zuiderent-Jerak, Teun
name: Gomes, Helena De Carvalho
name: Wichmann, Ole
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2017
Subjects: subject: 610 Medizin

description: Decisions in public health should be based on the best available evidence, reviewed and appraised using a rigorous and transparent methodology. The Project on a Framework for Rating Evidence in Public Health (PRECEPT) defined a methodology for evaluating and grading evidence in infectious disease epidemiology, prevention and control that takes different domains and question types into consideration. The methodology rates evidence in four domains: disease burden, risk factors, diagnostics and intervention. The framework guiding it has four steps going from overarching questions to an evidence statement. In step 1, approaches for identifying relevant key areas and developing specific questions to guide systematic evidence searches are described. In step 2, methodological guidance for conducting systematic reviews is provided; 15 study quality appraisal tools are proposed and an algorithm is given for matching a given study design with a tool. In step 3, a standardised evidence-grading scheme using the Grading of Recommendations Assessment, Development and Evaluation Working Group (GRADE) methodology is provided, whereby findings are documented in evidence profiles. Step 4 consists of preparing a narrative evidence summary. Users of this framework should be able to evaluate and grade scientific evidence from the four domains in a transparent and reproducible way.
“Why Reasonable Children Don’t Think that Nutcracker is Alive or that the Mouse King is Real"
Creators: name: Zunshine, Lisa
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Hoffmann, E. T. A. (Ernst Theodor Amadeus), 1776-1822
subject: Imagination
subject: Cognition
subject: Social perception
subject: Literature
subject: Romanticism
subject: Reason
subject: Metacognition
subject: Children
subject: Cognitive science

description: Zunshine’s essay draws on recent research in developmental psychology and cognitive evolutionary anthropology to examine emotional responses to supernatural events by the child and adult characters of E. T. A. Hoffmann’s The Nutcracker and the Mouse King (1816), as well as to revisit the traditional literary critical view of those responses, according to which the tale’s main protagonist, the seven-year-old Marie, possesses a “Romantic imagination” (in contrast to her philistine parents). Zunshine demonstrates, first, that Marie’s stubborn insistence on the reality of Nutcracker and the Mouse King is well in keeping with what developmental psychologists today would expect from children of her age group; and, second, that when Marie’s parents are called to comment on their daughter’s account of her magical adventures, their stodgy response is influenced by a very particular kind of social pressure under which they find themselves. While the essay’s primary goal is to emphasize the developmental and social aspects of the characters’ attitudes toward what is real, Zunshine also discusses the legitimacy of using recent research by cognitive scientists for examining the psychology and interpersonal dynamics of early nineteenth-century fictional characters.
"L’indicible dans la Recherche du temps perdu. Proust et le silence du corps "
Creators: name: Verna, Marisa
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Proust, Marcel, 1871-1922

description: Death, as well as sleep, seem to leave us facing the category of the unspeakable. This paper aims at studying Proust’s novel from this point of view, examining the paradox of a writing that crosses the threshold between what can be said and “what cannot be said but must nevertheless be heard” (Blanchot). We intend to analyze the discursive and rhetoric strategies that allow Proust to take up this challenge, overcoming the apparent aporia of language through the “fecundity” (Jankélévitch) of style, moving from the unutterable to the ineffable.
Campylobacter-Enteritis – Risikofaktoren und Infektionsquellen in Deutschland
Creators: name: Rosner, Bettina
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: Deutschland
subject: Campylobacter-Enteritis
subject: Risiko
subject: 610 Medizin

description: Campylobacter-Enteritiden sind Darmentzündungen, die durch Infektionen mit dem Bakterium Campylobacter verursacht werden. Typische Symptome sind Durchfall, starke Bauchschmerzen und Fieber. Auch Folgeerkrankungen wie reaktive Arthritis, Reizdarmsyndrom und neurologische Komplikationen wie das Guillain-Barré-Syndrom sind in seltenen Fällen möglich. In Deutschland ist der Nachweis des Krankheitserregers in Stuhlproben nach dem Infektionsschutzgesetz (IfSG) meldepflichtig. Mit mehr als 70.000 übermittelten Erkrankungen im Jahr 2016 und ähnlich hohen Zahlen in den Vorjahren (s. Abb. 1) ist die Campylobacter-Enteritis zur häufigsten bakteriellen meldepflichtigen Krankheit in Deutschland geworden.1 Auch europaweit liegt die Campylobacter-Enteritis unter den bakteriellen Krankheiten, die an die europäische Gesundheitsbehörde ECDC übermittelt werden, auf Rang eins.2 Am häufigsten sind Kinder unter fünf Jahren und junge Erwachsene zwischen 20 und 29 Jahren betroffen (s. Abb. 2, S. 502). Die überwiegende Mehrzahl der in Deutschland übermittelten Erkrankungen (92 %) wird auch in Deutschland erworben. Etwa 97 % der übermittelten Erkrankungen treten sporadisch auf, d. h. nur ein geringer Anteil der Erkrankungen wird als Krankheitsausbruch übermittelt, bei dem zwei oder mehr Erkrankungen in einem epidemiologischen Zusammenhang stehen.3
INVESTIGATION OF BIODEGRADABLE IRON-MANGANESE ALLOYS WITH VARIOUS POROSITY
Creators: name: Huang, Sabrina M
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Biomaterials
Metals and alloy materials

description: Bioresorbable iron-manganese (Fe-Mn) alloys are considered as a new class of biomaterials for the development of orthopedic fixation devices due to their promising mechanical properties, comparable to the human cortical bone, and the ability to degrade in the physiological environment and release small quantities of metallic ions/particles that are absorbable by the host. The greatest challenge for developing an ideal resorbable Fe-Mn alloy is to increase the degradation rate of the alloy without compromising the alloy biocompatibility, that is, causing zero or minimal local and systemic toxicity to the tissue. Another challenge is to improve osteo-integration through inducing a cascade of events leading to tissue ingrowth. The incorporation of porosity into the Fe-Mn alloys aimed to increase the corrosion rate and to provide the three-dimensional structure for cellular activity and nutrient transport. The Fe-30wt.%Mn alloys with 0-, 5-, 10-, and 60-volume percent porosity were produced through the space holder technique in powder metallurgy. The space-holder material, ammonium bicarbonate (NH4HCO3), was sieved to a particle size ranging 355~500 µm. The microstructures and mechanical properties of the alloys, as well as the influence of the degree of porosity on the alloy corrosion rates comparing to the concentrations of the degraded metal ions were investigated. Although the Fe-30Mn alloys containing 60-vol% porosity exhibited the lowest average ultimate compressive strength of 381 MPa among the tested groups, they were still mechanically stronger than a typical human wet compact bone. Furthermore, the alloys had the highest average corrosion rate of 0.98 ± 0.20 mm/year, compared to 0.13 ± 0.07 mm/year for the non-porous Fe-30Mn alloys. Nevertheless, the extract from the 60%-pore group had a cytotoxicity effect to the bone marrow stem cells (BMSCs) at an average normalized cell viability of 58%, which was below the standard viability of 70%, considered as cytotoxic in the indirect cytotoxicity study. The cytotoxicity study also corresponded to the highest level of transition metal ions Mn2+ released into the media for the 60%-pore group at an average ion released rate of 7 mg/day, compared to the other groups presenting similar Mn2+ released rates about 4 mg/day after 1 day of incubation. The extreme case of the 60%-pore group demonstrated the tradeoff between the corrosion rates and biocompatibility. On the other hand, the 10%-pore group showed an average ultimate compressive strength of 737 MPa comparable to the stainless steel 316L, an average corrosion rate of 0.260 ± 0.09 mm/year, which was 2-fold higher than the non-porous group, and an average cell viability of 86% close to the non-porous group. It is promising based on the above results, however, the osteo-integration of the 10%-pore group in terms of cell-to-cell and alloy-to-cell interactions was not ideal.
Additional file 2 of CircRNAs in diagnosis, prognosis, and clinicopathological features of multiple myeloma; a systematic review and meta-analysis
Creators: name: Mirazimi, Yasin
name: Aghayan, Amir Hossein
name: Keshtkar, Abbasali
name: Mottaghizadeh Jazi, Mahsa
name: Davoudian, Atefeh
name: Rafiee, Mohammad
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: Additional file 2: Figure S1. Quality assessment by the QUADAS II. Each bias risk item for each included study (A), each bias risk item is presented as a percentage for all included studies (B). Table S1. Supplemental Content, which illustrates study quality assessed via the Newcastle-Ottawa Scale checklist.
sj-pdf-1-hpq-10.1177_13591053211030994 – Supplemental material for The moderated associations of self-compassion with physiological and psychological stress responses: Comparisons between cancer caregivers and non-caregivers
Creators: name: Wai Wa Chan, Edward
name: Liang, Li
name: Huinan Liu, Nancy
name: Hou, Wai-Kai
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: sj-pdf-1-hpq-10.1177_13591053211030994 for The moderated associations of self-compassion with physiological and psychological stress responses: Comparisons between cancer caregivers and non-caregivers by Edward Wai Wa Chan, Li Liang, Nancy Huinan Liu and Wai- Kai Hou in Journal of Health Psychology
Drug survival of omalizumab in atopic asthma: Impact of clinical and genetic variables
Creators: name: Rojo-Tolosa, Susana
name: Caballero-Vázquez, Alberto
name: Pineda-Lancheros, Laura E.
name: Sánchez-Martínez, José A.
name: González-Gutiérrez, María V.
name: Jiménez-Gálvez, Gonzalo
name: Jiménez-Morales, Alberto
name: Morales-García, Concepción
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: It is estimated that 40–50% of severe asthma has an atopic basis, representing a clinical challenge and a significant economic burden for healthcare systems. The most effective treatment has emerged with the use of biologic therapies such as omalizumab; however, the rate of therapy switching due to loss of efficacy is high, which has a negative impact on the healthcare system. The aim was to evaluate the influence of genetic polymorphisms as predictors of omalizumab survival. We conducted a retrospective observational cohort study of 110 patients with uncontrolled severe allergic asthma treated with omalizumab in a tertiary hospital. We analyzed FCER1A (rs2251746, rs2427837), FCER1B (rs1441586, rs573790, rs1054485, rs569108), C3 (rs2230199), FCGR2A (rs1801274), FCGR2B (rs3219018, rs1050501), FCGR3A (rs10127939, rs396991), IL1RL1 (rs1420101, rs17026974, rs1921622) and GATA2 (rs4857855) by real-time PCR using Taqman probes. Drug survival was defined as the time from initiation to discontinuation of omalizumab. Cox regression analysis adjusted for the presence of respiratory disease, GERD, SAHS and years with asthma showed that the SNPs FCER1B rs573790 - CT (p < .001; HR = 3.38; CI95% = 1.66–6.87), FCGR3A rs10127939-AC (p = .018; HR = 3.85; CI95% = 1.25–11.81) and FCGR3A rs396991-CC (p = .020; HR = 2.23; CI95% = 1.14–4.38) were the independent variables associated with worse survival in patients diagnosed with asthma. A trend toward statistical significance was also found between and FCGR3A rs10127939-CC (p = .080; HR = 0.13; CI95% = 0.01–1.28) and longer drug survival. The results of this study demonstrate the potential influence of the polymorphisms studied on omalizumab survival and the clinical benefit that could be achieved by defining predictive biomarkers of drug survival.
"Lin Shu." The Chaucer Encyclopedia Edited by Richard Newhauser (Oxford: Wiley-Blackwell, 2023), pp. 1085-1086
Creators: name: Joubin, Alexa Alice
Publisher: name: Wiley-Blackwell
Year: 2023
Subjects: subject: Chaucer, Geoffrey, -1400
subject: China
subject: Translations
subject: Adaptations

description: Alexa Alice Joubin's entry expands the global scope of The Chaucer Encyclopedia (4 vols). This entry, in Volume 3, examines the work by the Chinese translator Lin Shu's (1852-1924). Lin translated and rewrote several key stories from the Canterbury Tales. Joubin argues that Lin's works exemplify early twentieth-century Chinese imaginaries of medieval England. Joubin conducted philological tracing to reveal that Lin based his rewritings on Charles Cowden Clarke's 1833 Tales from Chaucer in Prose, a prose rendition of ten tales intended for young audiences. Lin categorized most of the tales as fairy tales. Lin was the most prolific and influential translator of foreign literature in early twentieth-century China, who, in addition to rewriting Chaucer and Shakespeare (see shakespeare, william), rendered more than 180 Japanese, German, French, Spanish, and English dramas and novels into classical Chinese. Joubin's research shows that Lin's short stories rendered Chaucer in the Ming- and Qing-dynasty narrative tradition of love, filial piety, and exotic adventures. He applied a Confucian moral framework to turn Clarke's Victorian rewriting intended for women and children into stories for the predominantly male elites in China. Lin's texts gave the impression that Chaucer concentrated on fairies and ghosts. Lin used this strategic rewriting to counter the rhetoric deployed by those of his contemporaries who were in favor of totalWesternization and had been influenced by the Enlightenment and rationalism.
Supplemental Material, sj-pdf-2-vet-10.1177_03009858211013712 - International Guidelines for Veterinary Tumor Pathology: A Call to Action
Creators: name: Meuten, Donald J.
name: Moore, Frances M.
name: Donovan, Taryn A.
name: Bertram, Christof A.
name: Klopfleisch, Robert
name: Foster, Robert A.
name: Smedley, Rebecca C.
name: Dark, Michael J.
name: Milovancev, Milan
name: Stromberg, Paul
name: Williams, Bruce H.
name: Aubreville, Marc
name: Avallone, Giancarlo
name: Bolfa, Pompei
name: Cullen, John
name: Dennis, Michelle M.
name: Goldschmidt, Michael
name: Luong, Richard
name: Miller, Andrew D.
name: Miller, Margaret A.
name: Munday, John S.
name: Roccabianca, Paola
name: Salas, Elisa N.
name: Schulman, F. Yvonne
name: Laufer-Amorim, Renee
name: Asakawa, Midori G.
name: Craig, Linden
name: Dervisis, Nick
name: Esplin, D. Glen
name: George, Jeanne W.
name: Hauck, Marlene
name: Kagawa, Yumiko
name: Kiupel, Matti
name: Linder, Keith
name: Meichner, Kristina
name: Marconato, Laura
name: Oblak, Michelle L.
name: Santos, Renato L.
name: Simpson, R. Mark
name: Tvedten, Harold
name: Whitley, Derick
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental Material, sj-pdf-2-vet-10.1177_03009858211013712 for International Guidelines for Veterinary Tumor Pathology: A Call to Action by Donald J. Meuten, Frances M. Moore, Taryn A. Donovan, Christof A. Bertram, Robert Klopfleisch, Robert A. Foster, Rebecca C. Smedley, Michael J. Dark, Milan Milovancev, Paul Stromberg, Bruce H. Williams, Marc Aubreville, Giancarlo Avallone, Pompei Bolfa, John Cullen, Michelle M. Dennis, Michael Goldschmidt, Richard Luong, Andrew D. Miller, Margaret A. Miller, John S. Munday, Paola Roccabianca, Elisa N. Salas, F. Yvonne Schulman, Renee Laufer-Amorim, Midori G. Asakawa, Linden Craig, Nick Dervisis, D. Glen Esplin, Jeanne W. George, Marlene Hauck, Yumiko Kagawa, Matti Kiupel, Keith Linder, Kristina Meichner, Laura Marconato, Michelle L. Oblak, Renato L. Santos, R. Mark Simpson, Harold Tvedten and Derick Whitley in Veterinary Pathology
Additional file 1 of Dual-energy computed tomography in a multiparametric regression model for diagnosing lymph node metastases in pancreatic ductal adenocarcinoma
Creators: name: Li, Sheng
name: Jiang, Dongping
name: Jiang, Linling
name: Yan, Shumei
name: Liu, Lizhi
name: Ruan, Guangying
name: Zhou, Xuhui
name: Zhuo, Shuiqing
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Supplemental Figure 1. How LNs were identified in histopathology A: lymph nodes removed in different stations after pancreatic cancer surgery. B: A single lymph node resected with fat, with long diameter about 25mm. C. A metastatic lymph node from pancreatic cancer under microscopy (H&E stain; original magnification×40). D. The same LN(H&E stain; original magnification×400). Supplemental Table 1. The DECT parameters were included in the regression equation. Supplemental Table 2. Subgroup analysis about difference between LNs with typical feature and those without in terms of iodine density.
sj-pdf-1-hum-10.1177_00187267211030098 – Supplemental material for Working on my own: Measuring the challenges of gig work
Creators: name: Caza, Brianna B
name: Reid, Erin M
name: Ashford, Susan J
name: Granger, Steve
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-hum-10.1177_00187267211030098 for Working on my own: Measuring the challenges of gig work by Brianna B Caza, Erin M Reid, Susan J Ashford and Steve Granger in Human Relations
A systematic review and thematic synthesis exploring how gay, bisexual and other men who have sex with men (GBMSM) experience HPV and HPV vaccination
Creators: name: Pow, Janette
name: Clarke, Lewis
name: McHale, Sheona
name: Gray-Brunton, Carol
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: There are suboptimal levels of HPV vaccine uptake among gay, bisexual and men who have sex with men (GBMSM), despite the prevalence and incidence rates of HPV infection among GBMSM being higher than heterosexual males. This systematic review provides a thematic synthesis of qualitative research which examined the perceptions and experiences of GBMSM to HPV vaccine acceptability and explored the barriers and facilitators to participating in HPV vaccination. This review offers new insights about GBMSM understandings of HPV and how they are shaped by a complex relationship between limited knowledge and information of HPV, feminization of HPV with the focus on cervical cancer and women, and the socio-political governmentality of health services in meeting their health needs. Public health communication is required that focuses on the risks of HPV for anal, penile and oropharyngeal cancers and is culturally congruent to tailor and work with GBMSM more effectively for HPV vaccination. Healthcare providers need training around sexual health stigma and should proactively offer the HPV vaccination outside sexual health clinics for this vulnerable group.
Enhanced Class 8 Truck Platooning via Simultaneous Shifting and Model Predictive Control
Creators: name: Ibitayo, Ifeoluwa Jimmy
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Automation engineering
Control engineering
Autonomous vehicle systems
Control engineering, mechatronics and robotics not elsewhere classified

description: Class 8 trucks on average drive the most miles and consume the most fuel of any major vehicle category annually. Indiana specifically is the fifth busiest state for commercial freight traffic and moves $750 billion dollars of freight annually, and this number is expected to grow by 60% by 2040. Reducing fuel consumption for class 8 trucks would have a significant benefit on business and the proportional decrease in CO2 would be exceptionally beneficial for the environment.
Platooning is one of the most important strategies for increasing class 8 truck fuel savings. Platooning alone can help trucks save upwards of 7% platoon average fuel savings on flat ground. However, it can be difficult for a platooning controller to maintain a desired truck separation during uncoordinated shifting events. Using a high-fidelity simulation model, it is shown that simultaneous shifting–having the follow truck shift whenever the lead truck shifts (unless shifting would cause its engine to overspeed or underspeed)–decreases maximum truck separation by 24% on a moderately challenging grade route and 40% on a heavy grade route.
Model Predictive Control (MPC) of the follow truck is considered as a means to reduce the distance the follow truck falls behind during uncoordinated shifting events. The result in simulation is a reduction in maximum truck separation of 1% on a moderately challenging grade route and 19% on a heavy grade route. However, simultaneous shifting largely alleviates the need for MPC for the sake of tracking for the follow truck.
A different MPC formulation is considered to dynamically change the desired set point for truck separation for routes through a strategy called Route Optimized Gap Growth (ROGG). The result in simulation is 1% greater fuel savings on a moderately challenging grade route and 7% greater fuel savings on a route with heavy grade for the follow truck.
Global research trends on biomarkers for cancer immunotherapy: Visualization and bibliometric analysis
Creators: name: Qiao, Yuan
name: Xie, Dong
name: Li, Zhengxiang
name: Cao, Shaohua
name: Zhao, Dong
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy

description: The global burden of cancer continues to grow, posing a significant public health challenge. Although cancer immunotherapy has shown significant efficacy, the response rate is not high. Therefore, the objective of our research was to identify the latest research trends and hotspots on biomarkers from 1993 to 2023. Data were collected from the database Web of Science core collection. Bibliometric analysis and visualization were conducted with CiteSpace(6.3.1), VOSviewer (v1.6.20), R-bibliometrix(v4.3.3), and Microsoft Excel(2019). A total of 2686 literatures were retrieved. The sheer annual volume of publications has shown a rapid upward trend since 2015. The United States has generated the most publications and Harvard University ranked as a leading institution. The global biomarker research on immune checkpoint inhibitors (ICIs) revealed regional differences and in-depth explorations should be promoted in developing countries. Although China has become the second largest country in terms of publication, the average citation per paper and the total link strength were both lower than the other countries. The research on biomarkers mainly concentrated upon the following aspects: PD-1/PD-L1, CTLA-4, gene expression, adverse events, total mutational burden (TMB), body mass index (BMI), gut microbiota, cd8(+)/cd4(+) t-cells, and blood-related biomarkers such as lactate dehydrogenase (LDH), neutrophil–lymphocyte ratio (NLR), cytokines. Furthermore, “artificial intelligence” and “machine learning” have become the most important research hotspot over the last 2 y, which will help us to identify useful biomarkers from complex big data and provide a basis for precise medicine for malignant tumors.
Morphometric Analysis of Hippocampal Subfields
Creators: name: Cong, Shan
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Biomedical engineering not elsewhere classified
Digital processor architectures
Other information and computing sciences not elsewhere classified

description: Alzheimer's disease (AD) is an irreversible neurodegenerative brain disease distinguished by progressive impairment of memory and decline in cognitive abilities. The hippocampus is widely recognized to play essential roles in forming and gradually transferring information from short-term memory into long-term memory, and it is involved in the onset of the neuropathological pathways of the brain to suffer neuron loss in the rise of AD. Thus, hippocampal information obtained from magnetic resonance imaging (MRI) scans have been established as crucial AD biomarkers. The hippocampus is composed of multiple subfields, and the neuron loss is not uniformly distributed on the whole hippocampus. However, this critical subfield information is not addressed by the existing surface-based morphometry (SBM) and voxel-based morphometry (VBM) studies. Due to the size, complexity, heterogeneity, and folding anatomy of the hippocampus, acquiring volumetric and morphometric measures of hippocampal subfields usually presents not only technical challenges in quantitative neuroimaging but also analytical challenges. To address these challenges and deeply understand the relationships between hippocampal shape changes and brain disorders, especially to examine the degeneration of hippocampal subfields, this thesis focuses on constructing a hippocampal subfield morphometric analysis framework including the following aspects: 1) hippocampal subfield segmentation; 2) 3D shape modeling; 3) feature formulation; 4) diffeomorphic surface registration; 5) surface shape reconstruction; and 6) association analytics. The goals include developing accurate hippocampal subfield guided registration methods, extracting useful features and identifying significant subfields on the hippocampus that are highly related to cognitive disabilities, and using such information to assist early detection of AD.
« Proust et l’odeur de son temps »
Creators: name: Verna, Marisa
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Proust, Marcel, 1871-1922
subject: Odors

description: Until now, critics have shown little interest in the bouquet of aromas and scents that permeate the linguistic fabric of À la recherche du temps perdu , to the point of forming an olfactory (and cognitive) underlay. The aesthetic impact of these odors warrants further investigation, starting with a reconstruction of the “problem of smell” in Proust’s Paris. The treatment of smell in the novel seems, in fact, particularly subversive, against the backdrop of the physical and cultural atmosphere in which the novel was conceived and published. KEYWORDS – smell, sensory culture, breathing, miasma, 1900s Paris
Against Stereotypical Representations: On young Saudi directors
Creators: name: Nashef, Hania
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Feature films
subject: Saudi Arabia
subject: Popular culture

description: In his writing, Cultural theorist Stuart Hall has often argued that an image or a set of images has the capability of condensing a number of attributes into a single picture, producing a misleading representation of what other people and cultures are like. As a result, multiple stories evolve into the one story that is told repeatedly and usually by those in power. Monochrome and oversimplified representations of both people and place are not only often created and reinforced by dominant Western media but the practice of creating them continues to this day, resulting in the silencing of other potential stories. This paper, which will discuss Abdulelah Alqurashi’s Roll'em (2019), Shahad Ameen’s Scales (2019), Haifaa Al-Mansour’s The Perfect Candidate (2016) and Wadjda (2012) and Mahmoud Sabbagh’s Barakah Meets Barakah (2017), argues how these recent Saudi films challenge the prevalent media image and provide a counter-narrative to dominant stories.
Supplemental Material, sj-pdf-1-jbd-10.1177_01650254211022852 - The Japanese empathy questionnaire (EmQue) for preschool children: Psychometric properties and measurement invariance across gender
Creators: name: Takamatsu, Reina
name: Tsou, Yung-Ting
name: Kusumi, Takashi
name: Rieffe, Carolien
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental Material, sj-pdf-1-jbd-10.1177_01650254211022852 for The Japanese empathy questionnaire (EmQue) for preschool children: Psychometric properties and measurement invariance across gender by Reina Takamatsu, Yung-Ting Tsou, Takashi Kusumi and Carolien Rieffe in International Journal of Behavioral Development
Additional file 3 of CircRNAs in diagnosis, prognosis, and clinicopathological features of multiple myeloma; a systematic review and meta-analysis
Creators: name: Mirazimi, Yasin
name: Aghayan, Amir Hossein
name: Keshtkar, Abbasali
name: Mottaghizadeh Jazi, Mahsa
name: Davoudian, Atefeh
name: Rafiee, Mohammad
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: Additional file 3: Figure S1. Likelihood ratio scattergram (A), Relationship between pre and post-test probability based on the likelihood of a positive (above digonal line) or negative (below diagonal line) test (B), Fagan’s nomogram to describe the effect of circRNAs on the diagnosis of MM (C). Figure S2. Forest plots of Subgroup analysis based on DOR. Subgroup analysis based on type of circRNAs (A), Subgroup analysis based on quadas score (B).
Effects of turbulent flow regimes on pilot and perforated-plate stabilized lean premixed flames
Creators: name: Kim, Jupyoung
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Automotive combustion and fuel engineering
Chemical and thermal processes in energy and combustion

description: An experimental study of the effects of turbulent flow regime on the flame structure is conducted by using perforated-plate-stabilized hydrogen-piloted lean premixed methane/air turbulent flames. The underlying non-reacting turbulent flow field was investigated using two-dimensional three-components particle imaging velocimetry (2D3C-PIV) with and without three perforated plates. The non-reacting flow data allowed a separation of the turbulent flow regime into axial velocity dominated and vortex dominated flows. A plate with 62\% blockage ratio was used to represent the stream-dominant flow regime and another with 86\% blockage ratio was used to represent the vortex-dominant flow regime. OH laser-induced fluorescence was used to study the effects of the turbulent flow regime on the mean progress variable, flame brush thickness, flame surface density, and global consumption speed. In comparison with the stream-dominant flow, the vortex-dominant flow makes a wider and shorter flame. Also, the vortex-dominant flow has a thicker horizontal flame brush thickness and a thinner longitudinal flame brush thickness. Especially, the horizontal flame brush thickness for the vortex-dominant flow does not follow the turbulence diffusion theory. Then, the vortex-dominant flow shows a relatively constant flame surface density along the stream-wise direction, while the stream-dominant flow shows a decreasing flame surface density. Lastly, the vortex-dominant turbulent flow improves the consumption speed in comparison to the stream-dominant turbulent flow regime with the same velocity fluctuation level.
sj-pdf-1-jhc-10.1369_00221554211033239 – Supplemental material for Background-free Detection of Mouse Antibodies on Mouse Tissue by Anti-isotype Secondary Antibodies: Mouse on Mouse Ab Staining
Creators: name: Mascadri, Francesco
name: Ciccimarra, Roberta
name: Bolognesi, Maddalena M.
name: Stellari, Fabio
name: Ravanetti, Francesca
name: Cattoretti, Giorgio
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cell Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-jhc-10.1369_00221554211033239 for Background-free Detection of Mouse Antibodies on Mouse Tissue by Anti-isotype Secondary Antibodies: Mouse on Mouse Ab Staining by Francesco Mascadri, Roberta Ciccimarra, Maddalena M. Bolognesi, Fabio Stellari, Francesca Ravanetti and Giorgio Cattoretti in Journal of Histochemistry & Cytochemistry
Correlation between conventional and unconventional lipid parameters with the risk of progression of renal function decline: insights from the China Health and Retirement Longitudinal Study 2011–2015
Creators: name: Xin, Yijing
name: Wang, Yimeng
name: Shu, Yuyuan
name: Liang, Hanyang
name: Yang, Yanmin
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Virology

description: This study aimed to evaluate the association between conventional and unconventional lipid parameters and the risk of future chronic kidney disease (CKD) and progression of renal function decline. Data from 4,542 participants who were free of CKD at baseline were analyzed using information from the China Health and Retirement Longitudinal Study (2011–2015). The follow-up period was four years. The primary endpoints were incident CKD and rapid progression of renal function decline. The associations between lipid parameters and the risk of CKD and rapid progression of renal function decline were assessed using restricted cubic splines (RCS) and logistic regression analysis. Logistic regression analysis showed that high-density lipoprotein cholesterol (HDL-C) was negatively associated with CKD risk, while remnant cholesterol (RC) and the atherogenic index of plasma (AIP) were positively associated. Triglycerides (TG), RC, and AIP were positively correlated with rapid renal function decline, whereas low-density lipoprotein cholesterol (LDL-C) and HDL-C were negatively correlated. Among these parameters, AIP was the most strongly associated with CKD [adjusted odds ratio (OR) (95% CI): 2.091 (1.199, 3.649), p = 0.009] and rapid progression of renal function decline [adjusted OR (95% CI): 3.996 (2.632, 6.068), p < 0.001]. LDL-C and HDL-C were negatively associated with rapid progression of renal function decline, while TG, RC, and AIP were positively associated with this outcome. Among the lipid parameters examined, AIP was the most strongly associated with CKD and rapid progression of renal function decline.
Additional file 1 of Primary care involvement in clinical research – prerequisites, motivators, and barriers: results from a study series
Creators: name: Wangler, Julian
name: Jansky, Michael
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Biotechnology
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Additional file 1: Multimedia Appendix 1. Categorical system, qualitative in-depth study.
sj-pdf-1-aop-10.1177_10600280211032072 – Supplemental material for Association Between Potentially Inappropriate Medications and 30-Day Post–Hospital Discharge Outcomes in US Veterans
Creators: name: Allore, Heather G.
name: Gnjidic, Danijela
name: Skanderson, Melissa
name: Han, Ling
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-aop-10.1177_10600280211032072 for Association Between Potentially Inappropriate Medications and 30-Day Post–Hospital Discharge Outcomes in US Veterans by Heather G. Allore, Danijela Gnjidic, Melissa Skanderson and Ling Han in Annals of Pharmacotherapy