cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Assessing the Success of Analytics-led Interventions
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130303 Education Assessment and Evaluation
subject: FOS: Educational sciences

description: Analytics is an evidence-based methodology that prizes empirical information. As such it is appropriate that institutions should be able to provide an evidential foundation for the success of analytics itself. HEIs should seek to iteratively assess the effectiveness of their analytics strategy to ensure that it is having a positive impact on students’ experience. This document briefly discusses some of the considerations and challenges that should be born in mind when institutions are attempting analytical self-reflection.
The genetic basis of male mating success in the Yellow Fever mosquito, Aedes aegypti
Creators: name: Wyer, Claudia
Publisher: name: Imperial College London
Year: 2023

description: Aedes aegypti is responsible for the transmission of many emerging and re-emerging pathogens. Understanding Ae. aegypti mating behaviour and its genetic basis is important for the improvement and development of mosquito control strategies. While male mating success is intrinsically important in spreading desirable genes, sterility, or endosymbionts in reproductive control, we know relatively little about variation in the male mating success phenotype and its genetic basis. Through this thesis I investigated the variation in male mating success, using a novel assay designed to incorporate relevant sexual selection pressures, and estimated its heritability. I found evidence for a skew in male mating success, with very few males mating multiple times, despite the capacity to do so. Male mating success likely has a genetic basis, though the proportion of additive genetic variation contributing to the phenotype is low. I went on to use an experimental evolution and whole genome sequencing approach to demonstrate the role of sexual selection in shaping the Ae. aegypti genome. Manipulating the strength of sexual selection resulted in rapid genome-wide changes across all three chromosomes, with populations evolved in the presence of sexual selection retaining genomic similarity to their field-derived ancestors, which are predicted to have experienced strong sexual selection. I used gene ontology and functional effect analyses to show that many of the genes that responded consistently in all experimental replicates were associated with odour perception. I also identified a small number of potentially sexually selected genes that, after expression manipulation with RNAi, were tested for effects on male mating phenotypes. Males with reduced expression of one of these genes, pickpocket315, showed an altered mating phenotype, with males less likely to inseminate females, and making fewer attempts to mate overall. These results highlight that sexual selection is an important evolutionary force in Ae. aegypti mating systems, creating variation in phenotypes, and exerting a powerful effect on the genome. The results also have important consequences for those strategies that depend upon rearing mosquitoes en-masse for field release, and for the design of new mosquito control strategies that target mating behaviours.
Patterns of Risk and Protective Factors Among Alaska Children: Association With Maternal and Child Well-Being
Creators: name: Gottfredson, N.C.
name: Zolotor, A.J.
name: Marshall, S.W.
name: Shanahan, M.E.
name: Parrish, J.W.
name: Austin, A.E.
name: Halpern, C.T.
Publisher: name: Blackwell Publishing Inc.
Year: 2020

description: This study used population-representative data to examine associations of risk and protective factor patterns among Alaska Native/American Indian (AN/AI; N = 592) and non-Native (N = 1,018) children with maternal and child outcomes at age 3 years. Among AN/AI children, a high risk/moderate protection class was associated with child developmental risk and mothers being less likely to feel comfortable asking for help or knowing where to go for parenting information compared to a low socioeconomic status/high protection class. Among non-Native children, a moderate risk/high protection class was associated with child developmental risk and mothers being less likely to feel comfortable asking for help compared to a low risk/high protection class. Results provide insight on the intersection of risk and protective factors among Alaska families.
Atlanteco deliverable D9.2- Communication kit
Creators: name: Lextray Camille
name: Trabut Eloise
Publisher: name: Zenodo
Year: 2022

description: The Deliverable “Communication kit” is produced as part of the Work Package 9 “Communication, capacity building and outreach” and sets out to establish the initial media for communication to present the program and give communication tools for use by partners and media stakeholders. The tools presented in this document are made for different purposes and targets. Presentation document: used by partners to present the project during events, it can also be used by journalists and other media stakeholders to have an overview of AtlantECO. Project overview video: targeted towards the public. It will be used to present AtlantECO on digital platforms, social networks and during events. Public Newsletter: targets subscribed audience who are already interested in AtlantECO and used to engage with prospective audiences.
Praxisrelevante Empfehlungen für guten User Research in der Produktentwick-lung – Was ist guter User Research aus Sicht der Wissenschaft und der Praxis und was kann man daraus ableiten?
Creators: name: Trachsler, Sabrina
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2019
Subjects: HCD
Human-centered Design
UCD
User-centered Design
Produktentwicklung
UX
User Experience
User Research
User Research Methoden
User Research Methodenauswahl
Praxisrelevanz

description: User Experience (UX) respektive User Research (UR) PraktikerInnen in der Produktentwicklung stehen vor sich häufenden Herausforderungen. Agile Prozesse, multidisziplinäre Teams und Ressourcenknappheit prägen den UR. Die bestehende Problemlage im UR Praxisalltag, wie bei-spielsweise eine nicht kontinuierliche Integration von UR, zu wenig Einbezug von Endusern und dem Nutzungskontext sowie unzureichende UR Kompetenzen, legt nahe, dass die Wissenschaft die Praxis in der Umsetzung von gutem UR unterstützen sollte. Im Rahmen dieser Arbeit hat man mithilfe einer Dokumentenanalyse sowie einer Tagebuchstudie und Interviews mit UR Praktike-rinnen der Schweizerischen Bundesbahnen (SBB) ein Konzept mit praxisrelevanten Empfehlun-gen für guten UR entwickelt. Die Ergebnisse dieser Arbeit zeigen auf, wie die Wissenschaft und die Praxis guten UR beschreiben, welche UR Handlungspraktiken im Praxisalltag der SBB als erfolgreich eingeschätzt werden und wie UR Methoden bei der SBB ausgewählt werden. Daraus wurde ein Konzept für ein Tool entwickelt, das UR PraktikerInnen im herausfordernden UR Pra-xisalltag unterstützen soll. Der Konzeptvorschlag beinhaltet Grundprinzipien für guten UR, eine Sammlung von Handlungsfeldern für erfolgreichen UR in der Praxis und ein praxisrelevanter Ab-lauf der UR Methodenauswahl mit integrierten Auswahlkriterien.
Student Intervention Guide
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130303 Education Assessment and Evaluation
subject: FOS: Educational sciences

description: Learning analytics is only of benefit if it has an impact. The purpose of this resource is to enable institutions to achieve impact by planning effective analytics-led interventions. For a host of reasons, not least the fact that many of your analytics-led interventions will identify students with non-academic issues, institutions are STRONGLY advised to consider the themes below. Under each theme header, you’ll find further information including the questions that institutions should ensure that they know the answers to before staging even their first interventions.
Cohort Profile: The Zurich Project on the Social Development from Childhood to Adulthood (z-proso).
Creators: name: Ribeaud, Denis
name: Murray, Aja
name: Shanahan, Lilly
name: Shanahan, Michael J
name: Eisner, Manuel
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Aggressive behaviour
ADHD
Psychopathology
Violence
Juvenile Delinquency
Parenting
Developmental Psychology
Moral Development
Rct
Substance Use
Victimisation
Risk And Protective Factors
Socio-emotional Skills
Developmental Criminology
Legal Socialization
Field Experiment

description: Funder: University of Zurich
description: The Zurich Project on the Social Development from Childhood to Adulthood (z-proso) began in 2004 in response to the need for a better evidence base to support optimal child social development and prevent crime and violence. Since then, the study has tracked the development of a diverse sample of youths (N = 1,675 in the target sample; ~50% female) from age 7 (n = 1,360) to age 20 (n = 1,180), with primary data collection waves at ages 7, 8, 9, 10, 11, 12, 13, 15, 17, and 20. The study uses a multi-method, multi-informant design that combines teacher, youth, and parent reports with observational and behavioural measures, biosampling, functional imaging, and ecological momentary assessment. Analyses of the data have contributed important evidence to a diversity of topics in child and adolescent development, illuminating the developmental roots of crime and aggression, the impacts of exposure to different forms and combinations of victimisation, and trajectories of mental health and neurodevelopmental symptoms.
Guide to Data Quality
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130303 Education Assessment and Evaluation
subject: FOS: Educational sciences

description: A successful data analytics project requires a clean sample of data that is representative of the population of interest. The data typically comes from integrating a number of data sources, and the resulting dataset is rarely clean. This document discusses data quality issues that commonly arise in such as dataset, with examples from data typical of Higher Education.
Head Impact Biomechanics Differ Between Girls and Boys Youth Ice Hockey Players
Creators: name: Teel, E.F.
name: Marshall, S.W.
name: Mihalik, J.P.
name: Wasserman, E.B.
Publisher: name: Springer
Year: 2020

description: The influence of sex on head impact biomechanics is unknown for youth ice hockey. We sought to determine sex differences in head impact severity and frequency in youth ice hockey players. Male (n = 110) and female (n = 25) players (13–16 years old) were recruited from a local hockey organization. Players wore helmets instrumented with the Head Impact Telemetry System for all competitions and practices throughout the season. Seven team-seasons were captured. Random intercepts general mixed linear models determined whether linear acceleration and rotational acceleration differed by sex. Linear regression models evaluated the relationship between sex and impact frequency. All head impact biomechanics were natural log-transformed as their distributions were right-skewed. Females sustained fewer impacts per player than males (27 fewer impacts per player-season, p < 0.0001) even when analysis was limited to games only (21 fewer impacts per player-season, p < 0.0001). The linear acceleration was higher among females (1.07 g; 95% CI 1.00, 1.13; p = 0.04). There were no other meaningful sex differences in head impact severity. Female players are not permitted to body check, and this likely explains why they sustain fewer head impacts than males. However, as a result, females likely sustain a higher proportion of head impacts through illegal or unintentional head contact, and these impacts may result in more force being delivered to the head.
Quantitative assessment of point-of-care 3D-printed patient-specific polyetheretherketone (PEEK) cranial implants
Creators: name: Seiler, Daniel
name: Dalcanale, Federico
name: Sharma, Neha
name: Aghlmandi, Soheila
name: Zeilhofer, Hans-Florian
name: Thieringer, Florian
name: Honigmann, Philipp
Publisher: name: MDPI
Year: 2021
Subjects: Alloplastic implant
Biocompatible material
Computer-assisted
Cranioplasty
Fused filament fabrication
Reconstructive surgery
Patient-specific modeling
Printing
Polymer
Three-dimensional

description: Recent advancements in medical imaging, virtual surgical planning (VSP), and three-dimensional (3D) printing have potentially changed how today’s craniomaxillofacial surgeons use patient information for customized treatments. Over the years, polyetheretherketone (PEEK) has emerged as the biomaterial of choice to reconstruct craniofacial defects. With advancements in additive manufacturing (AM) systems, prospects for the point-of-care (POC) 3D printing of PEEK patient-specific implants (PSIs) have emerged. Consequently, investigating the clinical reliability of POC-manufactured PEEK implants has become a necessary endeavor. Therefore, this paper aims to provide a quantitative assessment of POC-manufactured, 3D-printed PEEK PSIs for cranial reconstruction through characterization of the geometrical, morphological, and biomechanical aspects of the in-hospital 3D-printed PEEK cranial implants. The study results revealed that the printed customized cranial implants had high dimensional accuracy and repeatability, displaying clinically acceptable morphologic similarity concerning fit and contours continuity. From a biomechanical standpoint, it was noticed that the tested implants had variable peak load values with discrete fracture patterns and failed at a mean (SD) peak load of 798.38 ± 211.45 N. In conclusion, the results of this preclinical study are in line with cranial implant expectations; however, specific attributes have scope for further improvements.
Moodle Course Hosting Data Logging and Reporting
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130303 Education Assessment and Evaluation
subject: FOS: Educational sciences

description: The purpose of this document is to outline the data that is collected on users of Moodle.
Head Impact Telemetry System's Video-based Impact Detection and Location Accuracy
Creators: name: Stitzel, J.D.
name: Luck, J.F.
name: Mihalik, J.P.
name: Boone, J.S.
name: Pinton, G.F.
name: Guskiewicz, K.M.
name: Marshall, S.W.
name: Campbell, K.R.
Publisher: name: Lippincott Williams and Wilkins
Year: 2020

description: Purpose This study aimed to quantify the Head Impact Telemetry (HIT) System's impact detection and location measurement accuracy using an impact biomechanics data set paired with video of high school football special teams plays. Methods The head impact biomechanics data set and video were collected from 22 high school football players, wearing HIT System instrumented helmets, competing in 218 special teams plays over a single high school football season. We used two separate video analysis approaches. To quantify the impact detection accuracy, we evaluated the video for head impacts independently of the impact data collection triggers collected by the HIT System. Video-observed impacts matched to valid and invalid head impacts by the HIT System algorithm were categorized as true positives, false positives, false negatives, and true negatives. To quantify impact location accuracy, we analyzed video-synchronized head impacts for impact location independent of the HIT System's impact location measurement and quantified the estimated percent agreement of impact location between the HIT System recorded impact location and the impact location observed on video. Results The HIT System's impact-filtering algorithm had 69% sensitivity, 72% specificity, and 70% accuracy in categorizing true and non-head impact data collection triggers. The HIT System agreed with video-observed impact locations on 64% of the 129 impacts we analyzed (unweighted k = 0.43, 95% confidence interval = 0.31-0.54). Conclusion This work provides data on the HIT System's impact detection and location accuracy during high school football special teams plays using game video analysis that has not been previously published. Based on our data, we believe that the HIT System is useful for estimating population-based impact location distributions for special teams plays.
Explanatory pragmatism: a context-sensitive framework for explainable medical AI.
Creators: name: Nyrup, Rune
name: Robinson, Diana
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Original Paper
Explainable artificial intelligence
XAI
Medical artificial intelligence
Explanation
Understanding
Ethics of artificial intelligence

description: Funder: microsoft research; doi: http://dx.doi.org/10.13039/100006112
description: Explainable artificial intelligence (XAI) is an emerging, multidisciplinary field of research that seeks to develop methods and tools for making AI systems more explainable or interpretable. XAI researchers increasingly recognise explainability as a context-, audience- and purpose-sensitive phenomenon, rather than a single well-defined property that can be directly measured and optimised. However, since there is currently no overarching definition of explainability, this poses a risk of miscommunication between the many different researchers within this multidisciplinary space. This is the problem we seek to address in this paper. We outline a framework, called Explanatory Pragmatism, which we argue has two attractive features. First, it allows us to conceptualise explainability in explicitly context-, audience- and purpose-relative terms, while retaining a unified underlying definition of explainability. Second, it makes visible any normative disagreements that may underpin conflicting claims about explainability regarding the purposes for which explanations are sought. Third, it allows us to distinguish several dimensions of AI explainability. We illustrate this framework by applying it to a case study involving a machine learning model for predicting whether patients suffering disorders of consciousness were likely to recover consciousness.
description: Leverhulme Trust (through Leverhulme Centre for the Future of Intelligence)
Open access dataset of task-free hemodynamic activity in 4-month-old infants during sleep using fNIRS
Creators: name: Blanco, Borja
name: Molnar, Monika
name: Carreiras, Manuel
name: Caballero-Gaudes, César
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Data Descriptor
/631/477
/706/689/477
data-descriptor

description: AbstractSpontaneous, task-free, hemodynamic activity of the brain provides useful information about its functional organization, as it can describe how different brain regions communicate to each other. Neuroimaging studies measuring the spontaneous activity of the brain are conducted while the participants are not engaged in a particular task or receiving any external stimulation. This approach is particularly useful in developmental populations as brain activity can be measured without the need for infant compliance and the risks of data contamination due to motion artifacts. In this project we sought to i) characterize the intrinsic functional organization of the brain in 4-month-old infants and ii) investigate whether bilingualism, as a specific environmental factor, could lead to adaptations on functional brain network development at this early age. Measures of spontaneous hemodynamic activity were acquired in 4-month-old infants (n = 104) during natural sleep using functional near-infrared spectroscopy (fNIRS). Emphasis was placed on acquiring high-quality data that could lead to reproducible results and serve as a valuable resource for researchers investigating the developing functional connectome.
Exploring the use of satellite Earth observation active wildland fire hotspot data via open access web platforms
Creators: name: Hope, Emily S.
name: McFayden, Colin B.
name: de Jong, Mark C.
name: Crowley, Morgan A.
name: Johnston, Joshua M.
name: Davies, Diane K.
name: Olsina, Otmar
name: Hewson, Jennifer
name: San-Miguel-Ayanz, Jesús
name: Ferrari, Davide
name: Sloane, Meghan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Globally, managing wildland fire is increasing in complexity. Satellite Earth Observation (EO) data, specifically active fire ‘hotspot’ data, is often used to inform wildland fire management. This study explores hotspot data usage via web traffic data (‘user counts’) for the FIRMS, GWIS and EFFIS web portals between September 2019 and April 2023. Global active fire data use is characterized by multi-month periods of relatively low, stable user counts, interspersed with periodic spikes (4.1x median monthly activity) of activity broadly aligned with the North American / European fire season (late summer-fall). Users from the Americas (45%) and Europe (36%) dominate web traffic. We also examined correlative relationships between web page user counts and environmental and social variables at multiple spatial scales. Globally, the strongest relationships were found between user counts and the total number of fires, total burned area, number of fire disaster events; country population levels and internet proliferation. Notably, at a country level, the strongest (and weakest) relationships between weekly user counts and fire activity were found in a diverse range of countries suggesting that a variety of hotspot data use situations exist and further investigation is needed to better understand EO active fire data usage.
Cancer and noncancer mortality among aluminum smelting workers in Badin, North Carolina
Creators: name: Robinson, W.R.
name: Vasudevan, P.
name: Richardson, D.
name: DeBono, N.
name: Marshall, S.W.
name: McClure, E.S.
Publisher: name: Wiley-Liss Inc.
Year: 2020

description: Background: Badin, North Carolina, hosted an aluminum smelting plant from 1917 to 2007. The Concerned Citizens of West Badin reported suspected excess cancer mortality among former employees. This study aimed to investigate these concerns. Methods: The study cohort was enumerated from United Steel Workers’ records of workers employed from 1980 to 2007. Cause-specific mortality rates in the cohort were compared with North Carolina population mortality rates using standardized mortality ratios (SMRs), standardized by age, sex, race, and calendar period. We estimated cause-specific adjusted standardized mortality ratios (aSMRs) using negative controls to mitigate healthy worker survivor bias (HWSB). Standardized rate ratios (SRRs) were calculated to compare mortality rates between workers ever employed vs never employed in the pot room. Results: All-cause mortality among Badin workers was lower than in the general population (SMR: 0.81, 95% confidence interval [CI]: 0.71-0.92). After adjusting for HWSB, excesses for all cancers (aSMR: 1.55, 95% CI: 1.10-2.21), bladder cancer (3.47, 95% CI: 1.25-9.62), mesothelioma (17.33, 95% CI: 5.40-55.59), and respiratory cancer (1.24, 95% CI: 0.77-1.99) were observed. Black males worked the highest proportion of their employed years in the pot room. Potroom workers experienced higher respiratory cancer (SRR: 2.99, 95% CI: 1.23-7.26), bladder cancer (SRR: 1.58, 95% CI: 0.15-15.28), and mesothelioma (SRR: 3.36, 95% CI: 0.21-53.78) mortality rates than never workers in the pot room. Conclusions: This study responds to concerns of a group of former aluminum workers. The results, while imprecise, suggest excess respiratory and bladder cancers among pot room workers in a contemporary cohort of union employees at a US smelter.
eIF6 rebinding dynamically couples ribosome maturation and translation.
Creators: name: Jaako, Pekka
name: Faille, Alexandre
name: Tan, Shengjiang
name: Wong, Chi C
name: Escudero-Urquijo, Norberto
name: Castro-Hartmann, Pablo
name: Wright, Penny
name: Hilcenko, Christine
name: Adams, David J
name: Warren, Alan
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/631/337/574/1789
/692/699/1541
/101/28
/64/24
/64/110
/13/31
article

description: Funder: Kay Kendall Leukaemia Fund
description: Funder: This work was supported by the Swedish Childhood Cancer Fund (PDS13/001, to PJ), the Swedish Research Council (2014-06807, to PJ), a Specialist Programme from Bloodwise (12048, to AJW), the UK Medical Research Council (MR/T012412/1, to AJW), European Cooperation in Science and Technology (COST) Action CA18233, “European Network for Innovative Diagnosis and treatment of Chronic Neutropenias, EuNet INNOCHRON” (to AJW), a Wellcome Trust strategic award to the Cambridge Institute for Medical Research (100140, to AJW), a core support grant from the Wellcome Trust and MRC to the Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, the Connor Wright Project, Ted’s Gang and the Cambridge National Institute for Health Research Biomedical Research Centre (BRC-1215-20014). The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care. A Wellcome Intermediate Fellowship (105914/Z/14/Z) and the Kay Kendall Leukaemia Fund (to CCW). We thank Dr. D. Y. Chirgadze for assistance with data collection at the Cryo-EM Facility, Department of Biochemistry, University of Cambridge, funded by the Wellcome Trust (206171/Z/17/Z; 202905/Z/16/Z), the Departments of Biochemistry and Chemistry, the Schools of Biological Sciences and Clinical Medicine and the University of Cambridge. We acknowledge Diamond Light Source for access and support of the cryo-EM facilities at the UK’s national Electron Bio-imaging Centre (eBIC) [under proposal EM BI22238], funded by the Wellcome Trust, MRC and BBRSC.
description: Protein synthesis is a cyclical process consisting of translation initiation, elongation, termination and ribosome recycling. The release factors SBDS and EFL1-both mutated in the leukemia predisposition disorder Shwachman-Diamond syndrome - license entry of nascent 60S ribosomal subunits into active translation by evicting the anti-association factor eIF6 from the 60S intersubunit face. We find that in mammalian cells, eIF6 holds all free cytoplasmic 60S subunits in a translationally inactive state and that SBDS and EFL1 are the minimal components required to recycle these 60S subunits back into additional rounds of translation by evicting eIF6. Increasing the dose of eIF6 in mice in vivo impairs terminal erythropoiesis by sequestering post-termination 60S subunits in the cytoplasm, disrupting subunit joining and attenuating global protein synthesis. These data reveal that ribosome maturation and recycling are dynamically coupled by a mechanism that is disrupted in an inherited leukemia predisposition disorder.
Strain Engineering of Single-Crystal Ferroelectric Membranes on Silicon and Flexible Platforms
Creators: name: Herrero, David Pesquera
Publisher: name: Zenodo
Year: 2022
Subjects: Ferroelectrics
Freestanding oxides
Ferroelectric memory
Strain engineering

description: Integration of crystalline oxides on CMOS and flexible platforms would boost the technological impact of these multifunctional materials by improving the capabilities of existing microelectronic devices. Chemical and structural incompatibility between semiconductors or flexible polymers and functional oxides makes this integration challenging via direct epitaxial growth. Recent developments on selective chemical etching and transfer processes, however, provide a new strategy to combine crystalline perovskite films with any substrate [1]. Here, we show that the high crystalline quality of epitaxial films grown on single-crystal substrates can be preserved after this transfer process, exemplified in membranes of the canonical ferroelectric BaTiO3. We also demonstrate that fine structural tuning can be obtained either by using interlayer stress in multilayer membranes or by mechanically manipulating the membranes supported by flexible polymer substrates, yielding wide control over ferroelectric (e.g., Curie temperature, remanent polarization, switching voltage, and switching speed) and dielectric properties [2]. We will discuss the possible future avenues that this fabrication process opens for the control of functional properties in oxide perovskites in general, and in ferroelectric oxides in particular. [1] D.Lu, et al. Nat. Mater. 15, 1255–1260 (2016). [2] D. Pesquera, et al. Adv. Mater. 32, 2003780 (2020).
Impact of youth sports specialisation on career and task-specific athletic performance: A systematic review following the American Medical Society for Sports Medicine (AMSSM) Collaborative Research Network's 2019 Youth Early Sport Specialisation Summit
Creators: name: Watson, A.
name: Beutler, A.I.
name: Kliethermes, S.A.
name: Jayanthi, N.
name: Marshall, S.W.
name: Nagle, K.
name: Herman, D.C.
name: Labella, C.R.
name: Faigenbaum, A.
name: Côté, J.
name: Feeley, B.
name: Malina, R.M.
name: Tenforde, A.
Publisher: name: BMJ Publishing Group
Year: 2020

description: Objective The impact, positive or negative, of youth sport specialisation (YSS) on short-Term and long-Term performance is not fully understood; however, the desire to maximise performance goals is generally considered the primary reason children and adolescents specialise at a young age. We performed a systematic review of original research to establish the association of YSS and task-focused or career-focused performance outcomes. Design Systematic review. Data sources Databases searched include PubMed, EMBASE, Cochrane, CINAHL and SPORTDiscus. Eligibility criteria We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to identify peer-reviewed research articles published in English between 1 January 1990 and 31 December 2018 that reported original findings on the association of YSS and performance outcomes. Studies without an explicit measure of sport specialisation, for example, volume measures without measuring sport specialisation, were excluded. Results Twenty-Two articles were included in the final review; 15 addressed career performance outcomes and 7 considered task performance outcomes. All identified studies were cross-sectional or retrospective in design. The proportion of elite athletes who specialised early ranged between 7% and 85%, depending on sport and definition of specialisation. Elite athletes often specialised between the ages of 14 and 15 compared with their non-elite or semi-elite peers who typically specialised prior to 13 years. In addition, neuromuscular control, anterior reach asymmetry and physical task outcomes did not differ by specialisation status. Conclusion The volume and methodological rigour of published research in this field are limited. Our review suggests that YSS is not required to achieve success at elite levels. YSS also does not appear to improve task-related performance (eg, anterior reach, neuromuscular control) outcomes for specialised athletes when compared with non-specialised athletes during childhood and adolescence.
Return to play and risk of repeat concussion in collegiate football players: Comparative analysis from the NCAA Concussion Study (1999-2001) and CARE Consortium (2014-2017)
Creators: name: Nelson, L.
name: McAllister, T.
name: Guskiewicz, K.M.
name: Marshall, S.W.
name: Harezlak, J.
name: Kudela, M.
name: Meier, T.
name: Katz, B.
name: Zhao, S.
name: Zhou, W.
name: McCrea, M.
name: Broglio, S.
name: CARE Consortium Investigators
Publisher: name: BMJ Publishing Group
Year: 2020

description: Objective We compared data from the National Collegiate Athletic Association (NCAA) Concussion Study (1999-2001) and the NCAA-Department of Defense Concussion Assessment, Research and Education (CARE) Consortium (2014-2017) to examine how clinical management, return to play (RTP) and risk of repeat concussion in collegiate football players have changed over the past 15 years. Methods We analysed data on reported duration of symptoms, symptom-free waiting period (SFWP), RTP and occurrence of within-season repeat concussion in collegiate football players with diagnosed concussion from the NCAA Study (n=184) and CARE (n=701). Results CARE athletes had significantly longer symptom duration (CARE median=5.92 days, IQR=3.02-9.98 days; NCAA median=2.00 days, IQR=1.00-4.00 days), SFWP (CARE median=6.00 days, IQR=3.49-9.00 days; NCAA median=0.98 days, IQR=0.00-4.00 days) and RTP (CARE median=12.23 days, IQR=8.04-18.92 days; NCAA median=3.00 days, IQR=1.00-8.00 days) than NCAA Study athletes (all p<0.0001). In CARE, there was only one case of repeat concussion within 10 days of initial injury (3.7% of within-season repeat concussions), whereas 92% of repeat concussions occurred within 10 days in the NCAA Study (p<0.001). The average interval between first and repeat concussion in CARE was 56.41 days, compared with 5.59 days in the NCAA Study (M difference=50.82 days; 95% CI 38.37 to 63.27; p<0.0001). Conclusion Our findings indicate that concussion in collegiate football is managed more conservatively than 15 years ago. These changes in clinical management appear to have reduced the risk of repetitive concussion during the critical period of cerebral vulnerability after sport-related concussion (SRC). These data support international guidelines recommending additional time for brain recovery before athletes RTP after SRC.
Learning Analytics Features In SAKAI
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130303 Education Assessment and Evaluation
subject: FOS: Educational sciences

description: This resource presents a high-level overview of the learning features available in SAKAI. It is intended as a brief and concise overview of the features and tools in SAKAI that contribute to learning analytics data gathering and presentation. There is also a reference to future developments and plans.
Learning Analytics Features in Blackboard
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130303 Education Assessment and Evaluation
subject: FOS: Educational sciences

description: Patrick Walsh of DIT has compiled an exhaustive suite of Blackboard resources that show the many features within the VLE that can be used to provide lecturers with data-driven insight into their students’ activities and learning behaviours. These can be used to identify students that may need additional support and to enable lecturers to provide timely and targeted support, resources and guidance. This guide gives a brief overview of three key Blackboard features, namely Module Reports, the Performance Dashboard and the Retention Center, but interested parties are strongly recommended to visit Patrick’s site at https://webcoursesanalytics.wordpress.com/workshop/ to see the full suite of resources. Users are reminded that all of the student data available within all VLEs counts as personal information and is subject to Data Protection legislation. Users must ensure that they are familiar with their rights and responsibilities under this legislation before accessing or using this data. Further information on Data Protection and its impact on Learning Analytics is available in ORLA.
Connections Between Opioids and Road Injury: Linkage of Prescription Monitoring and Crash Databases
Creators: name: Marshall, S.W.
name: Hezaveh, A.M.
name: Shiue, K.
name: Naumann, R.B.
name: Cherry, C.R.
Publisher: name: Elsevier Inc.
Year: 2020

description: Road traffic injuries and drug overdoses are the two leading causes of injury death in the U.S. In 2017, these two mechanisms were responsible for more than 100,000 deaths. Perhaps more importantly, these two leading causes of injury are closely interconnected. Opioids and other drugs affect driving abilities (e.g., reaction time, alertness, concentration) and crash-related injuries often result in opioid prescribing, creating a potential feedback loop from crash to injury to pain to opioid use and back to crash. At any given time, about 20% of drivers have a potentially impairing drug in their system.
Trunk and lower extremity movement patterns, stress fracture risk factors, and biomarkers of bone turnover in military trainees
Creators: name: Hackney, A.C.
name: Padua, D.A.
name: Mauntel, T.C.
name: Pietrosimone, B.G.
name: Trump, J.R.
name: Peck, K.Y.
name: Marshall, S.W.
name: Cameron, K.L.
Publisher: name: National Athletic Trainers' Association Inc.
Year: 2020

description: Context: Military service members commonly sustain lower extremity stress fractures (SFx). How SFx risk factors influence bone metabolism is unknown. Understanding how SFx risk factors influence bone metabolism may help to optimize risk-mitigation strategies. Objective: To determine how SFx risk factors influence bone metabolism. Design: Cross-sectional study. Setting: Military service academy. Patients or Other Participants: Forty-five men (agepre ¼ 18.56 6 1.39 years, heightpre ¼ 176.95 6 7.29 cm, masspre ¼ 77.20 6 9.40 kg; body mass indexpre ¼ 24.68 6 2.87) who completed Cadet Basic Training (CBT). Individuals with neurologic or metabolic disorders were excluded. Intervention(s): We assessed SFx risk factors (independent variables) with (1) the Landing Error Scoring System (LESS), (2) self-reported injury and physical activity questionnaires, and (3) physical fitness tests. We assessed bone biomarkers (dependent variables; procollagen type I amino-terminal propeptide [PINP] and cross-linked collagen telopeptide [CTx-1]) via serum. Main Outcome Measure(s): A markerless motion-capture system was used to analyze trunk and lower extremity biomechanics via the LESS. Serum samples were collected post-CBT; enzyme-linked immunosorbent assays determined PINP and CTx-1 concentrations, and PINP: CTx-1 ratios were calculated. Linear regression models demonstrated associations between SFx risk factors and PINP and CTx-1 concentrations and PINP: CTx-1 ratio. Biomarker concentration mean differences with 95% confidence intervals were calculated. Significance was set a priori using a ≤ .10 for simple and a ≤ .05 for multiple regression analyses. Results: The multiple regression models incorporating LESS and SFx risk factor data predicted the PINP concentration (R2 ¼ 0.47, P ¼ .02) and PINP: CTx-1 ratio (R2 ¼ 0.66, P ¼ .01). The PINP concentration was increased by foot internal rotation, trunk flexion, CBT injury, sit-up score, and pre- to post-CBT mass changes. The CTx-1 concentration was increased by heel-to-toe landing and post-CBT mass. The PINP: CTx-1 ratio was increased by foot internal rotation, lower extremity sagittal-plane displacement (inversely), CBT injury, sit-up score, and pre- to post-CBT mass changes. Conclusions: Stress fracture risk factors accounted for 66% of the PINP: CTx-1 ratio variability, a potential surrogate for bone health. Our findings provide insight into how SFx risk factors influence bone health. This information can help guide SFx risk-mitigation strategies.
title: Lo Stato digitale nel Piano Nazionale di Ripresa e Resilienza
Creators: name: Bontempi, Valerio
Publisher: name: Roma TrE-Press
Year: 2022

description: La stretta correlazione tra il difetto di produttività di un sistema-paese e il basso livello di digitalizzazione e innovazione dello stesso è noto. Così come è noto che in questo campo l’Italia abbia accumulato nel tempo un ritardo significativo. Non è un caso, del resto, che la Commissione europea collochi da anni l’Italia tra gli «innovatori moderati». I nostri livelli di spesa in Ricerca e Sviluppo (R&S) sono troppo bassi rispetto alla media europea e questo è vero sia per gli investimenti pubblici, sia per quelli privati. Proprio al fine di recuperare questo deficit italiano e di promuovere gli investimenti in tecnologie, infrastrutture e processi digitali, lo sforzo di digitalizzazione e innovazione permea di sé tutto il Piano Nazionale di Ripresa e Resilienza (PNRR). Nei diversi saggi che compongono il volume (suddivisi in tre sezioni: «Le competenze digitali, l’istruzione e la ricerca scientifica», «Le infrastrutture digitali» e «La digitalizzazione dell’attività amministrativa»), le Autrici e gli Autori tratteggiano le linee generali di tendenza del processo in atto di c.d. transizione digitale. A tal fine, appare imprescindibile l’operazione di ricostruzione dello ‘Stato digitale’ anche a partire dagli interventi previsti nel PNRR e dalla prima attuazione di questi. ‘Stato digitale’ che – è bene ricordare – deve essere inteso in una duplice accezione, ovvero sia come Stato che regola i processi di digitalizzazione in atto all’interno del sistema produttivo, sia come Stato che digitalizza se stesso.
Inter-Regional Open Science Cloud
Creators: name: Sherief
Publisher: name: Zenodo
Year: 2020
Subjects: open science cloud, federation, modular, inter-regional

description: Presentation made at the CODATA Beijing Conference In September 2019. EOSC and CSTClouds are regional clouds for Europe and China respectively. There are no guidelines and policy agreements for the construction of inter-regional open science Clouds . It is a challenge to construct the architecture of this cloud due to the absence of guidelines and agreed upon policies. This presentation provides a modular federated architecture whereby different kinds of guidelines and policies can be uploaded dynamically.
Moodle Course Hosting Data Logging and Reporting
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130303 Education Assessment and Evaluation
subject: FOS: Educational sciences

description: The purpose of this document is to outline the data that is collected on users of Moodle.
One-pot PEG-mediated syntheses of 2-(2-hydrazinyl) thiazole derivatives: novel route
Creators: name: Dattatraya G. Raut
name: Raghunath B. Bhosale
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology

description: Thiazoles are important sulfur-containing molecules that are widely used in diverse fields such as pharmaceuticals, agrochemicals, and material sciences. This is the first report on the PEG-300-mediated one-pot synthesis of 2-(2-hydrazinyl) thiazole derivatives from ketones, thiosemicarbazide, and α-halo ketones. Here PEG-300 acts as a solvent as well as supporting catalyst. Formation of compounds was confirmed by IR, 1H NMR, 13C NMR, and mass spectroscopic studies. A series of 2-(2-hydrazinyl) Thiazole derivatives have been synthesized from substituted ketones, thiosemicarbazide & α-halo ketones using PEG-300 as a reaction medium via one-pot approach.
Preconception and Prenatal Predictors of Early Experiences of Risk and Protection Among Alaska Children
Creators: name: Gottfredson, N.C.
name: Marshall, S.W.
name: Parrish, J.W.
name: Austin, A.E.
name: Zolotor, A.J.
name: Halpern, C.T.
name: Shanahan, M.E.
Publisher: name: Springer
Year: 2020

description: Objectives: Our objective was to identify preconception and prenatal predictors of early experiences of co-occurring risk and protective factors to help target prevention efforts to the highest-need families prior to the birth of the child. Methods: Data were from the Alaska Longitudinal Child Abuse and Neglect Linkage project and the 2012–2014 Alaska Child Understanding Behaviors Survey. We used latent class analysis and Vermunt’s three-step approach to examine predictors of latent classes of risk and protective factors among Alaska children. Results: Among children of Alaska Native/American Indian mothers, financial (OR 2.02, 95% CI 1.04, 3.90) and partner stress (OR 2.06, 95% CI 1.02, 4.10) prior to childbirth, maternal education < 12 years (OR 2.29, 95% CI 1.05, 4.96), and maternal substance use (OR 2.52, 95% CI 1.30, 4.89) were associated with a higher likelihood of membership in a high risk/moderate protection class as compared to a low socioeconomic status/high protection class. Among children of non-Native mothers, partner stress prior to childbirth (OR 3.92, 95% CI 1.08, 14.19), maternal education < 12 years (OR 2.69, 95% CI 1.24, 5.81), maternal substance use (OR 2.69, 95% CI 1.24, 5.81), younger maternal age (OR 0.87, 95% CI 0.80, 0.95), and a greater number of children (OR 1.62, 95% CI 1.09, 2.41) were associated with a higher likelihood of membership in a moderate risk/high protection class as compared to a low risk/moderate protection class. Conclusions: Results can inform eligibility criteria for prenatal home visiting programs and prenatal screening in Alaska to ensure prevention programming and referrals are directed to families most in need of additional support.
Integrating complex systems science into road safety research and practice, Part 2: Applying systems tools to the problem of increasing pedestrian death rates
Creators: name: Naumann, R.B.
name: Kumfer, W.
name: Lich, K.H.
name: Sandt, L.
name: Kuhlberg, J.
name: Marshall, S.W.
name: Heiny, S.
Publisher: name: BMJ Publishing Group
Year: 2020

description: Objectives To provide a specific example of how systems dynamics tools can increase understanding of stakeholder mental models' and generate robust systems-based hypotheses about the escalating problem of rising pedestrian death rates in the USA. Methods We designed and facilitated two group model building (GMB) workshops. Participants generated causal loop diagrams (CLDs) individually and in small groups to explore hypotheses concerning time-dynamic interacting factors underlying the increasing rates of pedestrian deaths. Using a grounded theory approach, research team members synthesised the structures and hypotheses into a single CLD. Results CLDs from the 41 participants indicated four core factors hypothesised to have a direct impact on pedestrian fatalities: pedestrian-vehicle crashes, vehicle speed at the time of the crash, vehicle size/dimensions and emergency response time. Participants diagrammed how actions and reactions impacted these proximal factors over time and led to ripple effects throughout a larger system to generate an increase in pedestrian deaths. Hypothesised contributing mechanisms fell within the following broad categories: community responses; research, policy and industry influence; potential unintended consequences of responses to pedestrian deaths; and the role of sprawl. Conclusions This application of systems science tools suggested several strategies for advancing injury prevention research and practice. The project generated robust hypotheses and advanced stakeholder communication and depth of understanding and engagement in this key issue. The CLD and GMB process detailed in this study provides a concrete example of how systems tools can be adopted and applied to a transportation safety topic.