title: ÐÐ°Ð·Ð¾Ð²ÑÐ¹ ÑÐµÐ½ÑÐ¾Ñ Ð´Ð»Ñ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð²ÑÐ´ÑÑ Ð°ÐµÐ¼Ð¾Ð³Ð¾ Ð²Ð¾Ð·Ð´ÑÑ Ð° Ð¸ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ Ð¾Ð½ÐºÐ¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ñ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ð¹ Ð»ÐµÐ³ÐºÐ¸Ñ , ÑÐ¾Ð·Ð´Ð°Ð½Ð½ÑÐ¹ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¿Ð¾Ð»ÑÐ¿ÑÐ¾Ð²Ð¾Ð´Ð½Ð¸ÐºÐ¾Ð²Ð¾Ð¹ ÑÑÑÑÐºÑÑÑÑ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Gas sensor for analysis of exhaled air and diagnostics of lung cancer, based on a semiconductor structure
Creators: name: Ð¡Ð°Ð²ÑÐµÐ½ÐºÐ¾, ÐÐ¼Ð¸ÑÑÐ¸Ð¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2020
Subjects: Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ° Ð¾Ð½ÐºÐ¾Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ð¹ Ð»ÑÐ³ÐºÐ¸Ñ
Ð½ÐµÐ¸Ð½Ð²Ð°Ð·Ð¸Ð²Ð½ÑÐµ Ð¼ÐµÑÐ¾Ð´Ñ
Â«ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð½ÑÐ¹ Ð½Ð¾ÑÂ»
Ð³Ð°Ð·Ð¾Ð²ÑÐ¹ ÑÐµÐ½ÑÐ¾Ñ
Ð°Ð´ÑÐ¾ÑÐ±ÑÐ¸Ñ
Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð¼Ð¾ÑÑÑ
ÑÐµÑÐµÐ¿ÑÐ¾ÑÐ½ÑÐ¹ ÑÐ»Ð¾Ð¹
Ð¿Ð¾ÑÑÐ¸ÑÐ¸Ð½
ÑÐ³Ð»ÐµÑÐ¾Ð´Ð½ÑÐµ Ð½Ð°Ð½Ð¾ÑÑÑÐ±ÐºÐ¸
Ð·Ð¾Ð»Ð¾ÑÑÐµ Ð½Ð°Ð½Ð¾ÑÐ°ÑÑÐ¸ÑÑ
Ð¿Ð¾Ð»ÐµÐ²Ð¾Ð¹ ÑÑÐ°Ð½Ð·Ð¸ÑÑÐ¾Ñ
diagnosis of lung cancer
non-invasive methods
electronic nose
gas sensor
adsorption
conductivity
receptor layer
porphyrin
carbon nanotubes
gold nanoparticles
field effect transistor

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÑÐ¼ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ Ð¾Ð½ÐºÐ¾Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ð¹ Ð»ÐµÐ³ÐºÐ¸Ñ, ÑÑÐ²ÑÑÐ²Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð½Ð°Ð½Ð¾ÑÑÑÑÐºÑÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð² Ð² ÑÐµÐ½ÑÐ¾ÑÐ°Ñ-Ð°Ð½Ð°Ð»Ð¸Ð·Ð°ÑÐ¾ÑÐ°Ñ Ð²ÑÐ´ÑÑÐ°ÐµÐ¼Ð¾Ð³Ð¾ Ð²Ð¾Ð·Ð´ÑÑÐ°, ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸ ÑÐµÐ½ÑÐ¾ÑÐ°-Ð°Ð½Ð°Ð»Ð¸Ð·Ð°ÑÐ¾ÑÐ° Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¿Ð¾Ð»ÐµÐ²ÑÑ ÑÑÐ°Ð½Ð·Ð¸ÑÑÐ¾ÑÐ¾Ð² Ð½Ð° Ð½Ð°Ð½Ð¾ÑÑÑÑÐºÑÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ°Ñ. Ð Ð°Ð±Ð¾ÑÐ° ÑÐ¾Ð´ÐµÑÐ¶Ð¸Ñ Ð¾Ð±Ð·Ð¾Ñ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÐ¾ÑÑÐ¾ÑÐ½Ð¸Ñ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² ÑÐ°Ð½Ð½ÐµÐ¹ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ Ð¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ¾Ð² ÑÐ°ÐºÐ° Ð»ÐµÐ³ÐºÐ¸Ñ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¾Ð±Ð½Ð°ÑÑÐ¶ÐµÐ½Ð¸Ñ Ð¾Ð½ÐºÐ¾Ð¼Ð°ÑÐºÐµÑÐ¾Ð² Ð² Ð²ÑÐ´ÑÑÐ°ÐµÐ¼Ð¾Ð¼ Ð²Ð¾Ð·Ð´ÑÑÐµ Ð¸ Ð² ÐºÐ¾Ð½Ð´ÐµÐ½ÑÐ°ÑÐµ, Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð´Ð¸ÑÑÐµÑÐµÐ½ÑÐ¸Ð°ÑÐ¸Ð¸ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð¾Ð½ÐºÐ¾Ð¼Ð°ÑÐºÐµÑÐ¾Ð² Ð¿Ð¾ Ð¾ÑÐºÐ»Ð¸ÐºÑ ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð² Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÑÐµÐ¼Ð¾Ð³Ð¾ Ð¿ÑÐ¸Ð±Ð¾ÑÐ°. ÐÐÐ  Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð»Ð°ÑÑ Ð¿Ð¾ÑÑÐµÐ´ÑÑÐ²Ð¾Ð¼ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐ°Ð±Ð¾ÑÑ ÑÐµÐ½ÑÐ¾ÑÐ°-Ð°Ð½Ð°Ð»Ð¸Ð·Ð°ÑÐ¾ÑÐ° Ð¸ Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ¸ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð±ÑÐ»Ð¾ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð¾ ÑÐ»ÑÑÑÐµÐ½Ð¸Ðµ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÐµÐ¹ ÑÐµÐ½ÑÐ¾ÑÐ°-Ð°Ð½Ð°Ð»Ð¸Ð·Ð°ÑÐ¾ÑÐ° Ð¿ÑÐ¸ Ð·Ð°Ð¼ÐµÐ½Ðµ ÑÐµÑÐµÐ¿ÑÐ¾ÑÐ½Ð¾Ð³Ð¾ ÑÐ»Ð¾Ñ Ð² ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸ ÑÑÐ°Ð½Ð·Ð¸ÑÑÐ¾ÑÐ° Ð½Ð° ÑÐ³Ð»ÐµÑÐ¾Ð´Ð¾ÑÐ¾Ð´ÐµÑÐ¶Ð°ÑÐ¸Ð¹ ÑÐ»ÐµÐ¼ÐµÐ½Ñ. ÐÑÐ´ÐµÐ»ÐµÐ½Ñ ÑÐ²Ð½ÑÐµ Ð·Ð°Ð²Ð¸ÑÐ¸Ð¼Ð¾ÑÑÐ¸ Ð¸ Ð¾Ð¿Ð¸ÑÐ°Ð½Ñ ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¿ÑÐ¾ÑÐµÑÑÑ, Ð¿ÑÐ¾ÑÐµÐºÐ°ÑÑÐ¸Ñ Ð² Ð³Ð°Ð·Ð¾Ð²Ð¾Ð¼ Ð¼ÑÐ»ÑÑÐ¸ÑÐµÐ½ÑÐ¾ÑÐµ Ð½Ð° Ð¿Ð¾Ð»ÐµÐ²ÑÑ ÑÑÐ°Ð½Ð·Ð¸ÑÑÐ¾ÑÐ°Ñ. Ð ÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ ÐÐÐ  Ð¼Ð¾Ð³ÑÑ Ð±ÑÑÑ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ñ Ð´Ð»Ñ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¿ÑÐ¸Ð±Ð¾ÑÐ¾Ð² ÑÐ¸Ð¿Ð° Â«ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð½ÑÐ¹ Ð½Ð¾ÑÂ». ÐÐ±Ð»Ð°ÑÑÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÑÑÑÑ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¸ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° ÑÐ¸Ð¼Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¾ÑÑÐ°Ð²Ð° Ð²ÑÐ´ÑÑÐ°ÐµÐ¼Ð¾Ð³Ð¾ Ð²Ð¾Ð·Ð´ÑÑÐ°, Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ° Ð¾Ð½ÐºÐ¾Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ð¹, Ð´ÐµÑÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÐÐÐ¡ Ð² Ð²ÑÐ´ÑÑÐ°ÐµÐ¼Ð¾Ð¼ Ð²Ð¾Ð·Ð´ÑÑÐµ. ÐÐ°Ð·Ð¾Ð²ÑÐµ Ð°Ð½Ð°Ð»Ð¸Ð·Ð°ÑÐ¾ÑÑ ÐÐ Ð´Ð»Ñ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ ÑÐ°ÐºÐ° Ð»ÑÐ³ÐºÐ¸Ñ ÑÐ²Ð»ÑÑÑÑÑ Ð²Ð¿Ð¾Ð»Ð½Ðµ ÑÐµÐ°Ð»Ð¸Ð·ÑÐµÐ¼Ð¾Ð¹ Ð¸ Ð¿ÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ð½Ð¾Ð¹ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÐµÐ¹, ÐºÐ¾ÑÐ¾ÑÐ°Ñ Ð² Ð¿Ð¾ÑÐ»ÐµÐ´Ð½Ð¸Ðµ Ð³Ð¾Ð´Ð° ÑÑÐ°Ð»Ð° Ð¿Ð¾Ð»ÑÑÐ°ÑÑ Ð²ÑÑ Ð±Ð¾Ð»ÑÑÐ¸Ð¹ ÑÐ¿ÐµÐºÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¹.
description: This work is devoted to the features of the diagnosis of lung cancer, the sensitivity of nanostructured elements in sensors-analyzers of exhaled air, the design of the sensor analyzer based on field-effect transistors on nanostructured elements. The work contains a review of the current state of early diagnostic methods and lung cancer tools based on the detection of tumor markers in exhaled air and in condensate, a study of the differentiation of various tumor markers by the response of the electrical parameters of the designed device. Final qualification work was carried out by modeling the operation of the sensoranalyzer and processing the simulation results. As a result, it was proposed to improve the performance of the sensor analyzer when replacing the receptor layer in the transistor design with a carbon-containing element. Explicit dependences are identified and the physical processes occurring in a gas multisensor using field effect transistors are described. The results of the final qualification work can be used to increase the efficiency of electronic nose devices. The field of research is technologies for analyzing the chemical composition of exhaled air, the diagnosis of cancer, the detection of VOCs in exhaled air. Gas analyzers Respiratory air for the diagnosis of lung cancer is a very feasible and promising technology, which in recent years has begun to receive a wider range of studies.