cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The application of a structured design process to a new CCTV camera-based product
Creators: name: Holdgate, James A.
Publisher: name: Loughborough University
Year: 2022
Subjects: subject: 91399 Mechanical Engineering not elsewhere classified
subject: FOS: Mechanical engineering

description: This thesis deduces an effective strategy for researching, specifying, designing and manufacturing a relatively complex multi-disciplinary product within a typical small to medium sized manufacturing environment. This is achieved through use of a case study project carried out in a specific manufacturing company. The case study was not a simulation but a live and business critical project carried out in time scales dictated by the company. Although the existing product development process was not obviously detrimental to many of the smaller projects carried out within the company, it would be inadequate for the successful design and development of the impending new, innovative and relatively complex product within case study. First, the existing company design culture is considered to gain an understanding of the company procedures, and the resources, tools and personnel available. Then the brief for the proposed product is explored at a reasonably high level. The nature of the design process itself is discussed, including research into the theoretical tools and models that can be used to aid the design process. These considerations allow the formulation of a new design approach that would suit the company, its circumstances, and the proposed product. Following this there is an account of the case study, describing the process that was followed to reach the final solution. This is the design of a CCTV camera, but more accurately the design of a platform product that would provide two new mechanism driven features that would contribute to making it the most advanced camera on the market. The case study is then reviewed, firstly to assess the success of the product (the failure of the project to finish within time scales is an indication of the resistance to the new approach), and secondly to consider the issues of implementation (where it was successful, where there was resistance, and where there were limits in resources and management support). Using the information gained from this review, a refined new product design model is defined that would be closer to a generic model suiting all manufacturing companies of this type. However, as the approach is based on the observation of one company and one project, it is indicated the further research would be required to validate the refinements.
Perspectives on deprescribing in older people with type 2 diabetes and/or cardiovascular conditions: challenges from healthcare provider, patient and caregiver perspective, and interventions to support a proactive approach
Creators: name: Denig, Petra
name: Stuijt, Peter J. C.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: For people with type 2 diabetes and/or cardiovascular conditions, deprescribing of glucose-lowering, blood pressure-lowering and/or lipid-lowering medication is recommended when they age, and their health status deteriorates. So far, deprescribing rates of these so-called cardiometabolic medications are low. A review of challenges and interventions addressing these challenges in this population is pertinent. We first provide an overview of relevant deprescribing recommendations. Next, we review challenges for healthcare providers (HCPs) to deprescribe cardiometabolic medication and provide insight in the patient and caregiver perspective on deprescribing. We summarize findings from research on implementing deprescribing of cardiometabolic medication and reflect on strategies to enhance deprescribing. We have used a combination of methods to search for relevant articles. There is a need for rigorous development and evaluation of intervention strategies aimed at proactive deprescribing of cardiometabolic medication. To address challenges at different levels, these should be multifaceted interventions. All stakeholders must become aware of the relevance of deintensifying medication in this population. Education and training for HCPs and patients should support patient-centered communication and shared decision-making. Development of procedures and tools to select eligible patients and conduct targeted medication reviews are important for implementation of deprescribing in routine care.
Pa teuan me da zonjal
Creators: name: Musée National Des Arts Et Traditions Populaires (Paris)
name: Centre D'ethnologie Française
Publisher: name: École des Hautes Études en Sciences Sociales; Institut  interdisciplinaire d'anthropologie du contemporain (Paris); Laboratoire d'anthropologie et d'histoire de l'institution de la culture (Paris)
Year: 2024

Abstract
Longevity of complete dentures after relines: A 20-year population based retrospective study of 187,227 publicly insured adults
Creators: name: Taylor, Marietta
name: Masood, Mohd
name: Mnatzaganian, George
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3203
subject: Dentistry
subject: FOS: Clinical medicine

description: No description supplied
Kaera tra ar maeziou
Creators: name: Musée National Des Arts Et Traditions Populaires (Paris)
name: Centre D'ethnologie Française
Publisher: name: École des Hautes Études en Sciences Sociales; Institut  interdisciplinaire d'anthropologie du contemporain (Paris); Laboratoire d'anthropologie et d'histoire de l'institution de la culture (Paris)
Year: 2024

Abstract
Perspectives on deprescribing in older people with type 2 diabetes and/or cardiovascular conditions: challenges from healthcare provider, patient and caregiver perspective and interventions to support a proactive approach
Creators: name: Denig, Petra
name: Stuijt, Peter J.C.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: For people with type 2 diabetes and/or cardiovascular conditions, deprescribing of glucose-lowering, blood pressure-lowering and/or lipid-lowering medication is recommended when they age, and their health status deteriorates. So far, deprescribing rates of these so-called cardiometabolic medications are low. A review of challenges and interventions addressing these challenges in this population is pertinent. We first provide an overview of relevant deprescribing recommendations. Next, we review challenges for healthcare providers (HCPs) to deprescribe cardiometabolic medication and provide insight in the patient and caregiver perspective on deprescribing. We summarize findings from research on implementing deprescribing of cardiometabolic medication and reflect on strategies to enhance deprescribing. We have used a combination of methods to search for relevant articles. There is a need for rigorous development and evaluation of intervention strategies aimed at proactive deprescribing of cardiometabolic medication. To address challenges at different levels, these should be multifaceted interventions. All stakeholders must become aware of the relevance of deintensifying medication in this population. Education and training for HCPs and patients should support patient-centered communication and shared decision-making. Development of procedures and tools to select eligible patients and conduct targeted medication reviews are important for implementation of deprescribing in routine care.
Selaouit hag e klefot
Creators: name: Musée National Des Arts Et Traditions Populaires (Paris)
name: Centre D'ethnologie Française
Publisher: name: École des Hautes Études en Sciences Sociales; Institut  interdisciplinaire d'anthropologie du contemporain (Paris); Laboratoire d'anthropologie et d'histoire de l'institution de la culture (Paris)
Year: 2024

Abstract
Teaching the care of older people in Australian nursing schools: Survey findings
Creators: name: Fetherstonhaugh, Deirdre
name: Rayner, Jo-Anne
name: Solly, Kane
name: Beattie, E
name: Harrington, A
name: Jeon, YH
name: Moyle, W
name: Parker, D
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 3901
subject: Curriculum and pedagogy
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems
classificationCode: 4204
subject: Midwifery
classificationCode: 4205
subject: Nursing

description: Background: Meeting the complex health needs of an increasing number of older people is a critical workforce challenge for the Australian health and aged care sectors. Nurses are the largest group of registered health care professionals and fundamental to delivering health and aged care in Australia. However, while nursing students encounter increasing numbers of older people in all health and aged care settings, little is known about how they are educationally prepared to care for them. Aim: To investigate the curriculum content and method of teaching the care of older people in Australian Bachelor of Nursing degrees. Methods: A population sample of all Australian nursing schools offering Bachelor of Nursing degrees. Nurse academics involved in subject coordination or curriculum development were recruited. A telephone-assisted survey explored ‘the care of older people’ in Australian undergraduate nursing curricula. Descriptive statistical analyses were undertaken. Results: The response rate was 100%. Curricula were acute care focused with content specific to the care of older people scaffolded across curricula. A variety of teaching and learning methods were reported. Clinical experiences with older people occurred in residential aged care settings, generally in the first year of the degree. Conclusions: Preparation of pre-registration nurses for the care of older people requires improvement in curricula content and clinical experience to equip graduates to provide safe, person-centred care that meets the needs of older Australians.
A conceptual model of risk and protective factors for autistic burnout
Creators: name: Mantzalas, Jane
name: Richdale, Amanda
name: Dissanayake, Cheryl
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 3209
subject: Neurosciences
subject: FOS: Clinical medicine
classificationCode: 320999
subject: Neurosciences not elsewhere classified
classificationCode: 420313
subject: Mental health services
classificationCode: 480707
subject: Welfare, insurance, disability and social security law
classificationCode: 52
subject: Psychology
subject: FOS: Psychology
classificationCode: 5201
subject: Applied and developmental psychology
classificationCode: 5203
subject: Clinical and health psychology

description: No description supplied
Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
Creators: name: T. Diepstraten, Sarah
name: Yuan, Yin
name: La Marca, John E.
name: Young, Savannah
name: Chang, Catherine
name: Whelan, Lauren
name: Ross, Aisling M.
name: C. Fischer, Karla
name: Pomilio, Giovanna
name: Morris, Rhiannon
name: Georgiou, Angela
name: Litalien, Veronique
name: Brown, Fiona C.
name: W. Roberts, Andrew
name: Strasser, Andreas
name: Wei, Andrew H.
name: L. Kelly, Gemma
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: TP53-mutant blood cancers remain a clinical challenge. BH3-mimetic drugs inhibit BCL-2 pro-survival proteins, inducing cancer cell apoptosis. Despite acting downstream of p53, functional p53 is required for maximal cancer cell killing by BH3-mimetics through an unknown mechanism. Here, we report p53 is activated following BH3-mimetic induced mitochondrial outer membrane permeabilization, leading to BH3-only protein induction and thereby potentiating the pro-apoptotic signal. TP53-deficient lymphomas lack this feedforward loop, providing opportunities for survival and disease relapse after BH3-mimetic treatment. The therapeutic barrier imposed by defects in TP53 can be overcome by direct activation of the cGAS/STING pathway, which promotes apoptosis of blood cancer cells through p53-independent BH3-only protein upregulation. Combining clinically relevant STING agonists with BH3-mimetic drugs efficiently kills TRP53/TP53-mutant mouse B lymphoma, human NK/T lymphoma, and acute myeloid leukemia cells. This represents a promising therapy regime that can be fast-tracked to tackle TP53-mutant blood cancers in the clinic.
title: Enzymatic synthesis of semi-IPNs within hydrogel-based microfluidics
Creators: name: Jiao, Chen
name: Appelhans, Dietmar
name: Voit, Brigitte
name: Bruns, Nico
name: Gaitzsch, Jens
Publisher: name: The Royal Society of Chemistry
Year: 2025

description: With the goal of achieving environmentally friendly polymer synthesis strategies, enzyme-promoted polymerisation has gradually attracted people's attention. The development of hydrogel-based microfluidics provides a new carrier system for enzymatic catalysis. Here, we report a new technique for enzyme-promoted free radical polymerisation, supported on hydrogel microdots (μHDs) within a microfluidic chip. Free radical polymerisation initiated by free horseradish peroxidase (HRP) in vials confirmed the formation of poly(N-isopropyl acrylamide) (PNiPAAm), achieving high molecular weight (500 000 Da) in 5 min. For polymerisation in microfluidics, disulphide-bearing μHDs were mounted on a PDMS-on-glass chip. Utilising a disulphide-thiol exchange reaction, modified HRP was then captured “from the flow” through the chip, which was confirmed by fluorescence microscopy. Various polymerisation parameters were studied in the microfluidic chip, and the successful polymer formation was confirmed by copolymerisation with a fluorescent comonomer. The physical entanglement fixed the formed polymer on the μHDs, forming a structure similar to a semi-interpenetrating network (semi-IPN). Thus, this technique provides a new direct approach to achieving semi-IPNs within microfluidic chips, showcasing the versatility in which microfluidic systems can be utilised.
A conceptual model of risk and protective factors for autistic burnout
Creators: name: Mantzalas, Jane
name: Richdale, Amanda
name: Dissanayake, Cheryl
Publisher: name: La Trobe
Year: 2023

description: Early qualitative research indicates that autistic burnout is commonly experienced by autistic people and is associated with significant, negative consequences for their mental health, wellbeing, and quality of life, including suicidality. Findings to date suggest that factors associated with being autistic and the widespread lack of autism awareness and acceptance within society contribute to the onset and recurrence of autistic burnout. Based on autistic adults' descriptions of their lived experiences, a Conceptual Model of Autistic Burnout (CMAB) is proposed, which describes a series of hypothesized relationships between identified risk and protective factors that may contribute to, or buffer against, autistic burnout. The theoretical framework for the CMAB is based on the Social-Relational model of disability and neurodiversity paradigm, and the Job Demands-Resources model of burnout, and Conservation of Resources theory. The CMAB offers a holistic perspective for understanding individual, social, and environmental factors that can influence autistic burnout via various direct and indirect pathways. Autistic burnout research is in its infancy and the CMAB provides a foundation for future investigations about this condition. Lay Summary: Although many autistic people describe experiencing autistic burnout, there has been little research on this topic. Based on descriptions of autistic peoples' lived experiences, we developed a conceptual model to explore how various risk and protective factors may interact to contribute to, or prevent, autistic burnout.
Recovery of mitogenomes from whole genome sequences to infer maternal diversity in 1883 modern taurine and indicine cattle
Creators: name: Dorji, Jigme
name: Vander Jagt, CJ
name: Chamberlain, Amanda
name: Cocks, Benjamin
name: MacLeod, Iona
name: Daetwyler, Hans
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3105
subject: Genetics

description: Maternal diversity based on a sub-region of mitochondrial genome or variants were commonly used to understand past demographic events in livestock. Additionally, there is growing evidence of direct association of mitochondrial genetic variants with a range of phenotypes. Therefore, this study used complete bovine mitogenomes from a large sequence database to explore the full spectrum of maternal diversity. Mitogenome diversity was evaluated among 1883 animals representing 156 globally important cattle breeds. Overall, the mitogenomes were diverse: presenting 11 major haplogroups, expanding to 1309 unique haplotypes, with nucleotide diversity 0.011 and haplotype diversity 0.999. A small proportion of African taurine (3.5%) and indicine (1.3%) haplogroups were found among the European taurine breeds and composites. The haplogrouping was largely consistent with the population structure derived from alternate clustering methods (e.g. PCA and hierarchical clustering). Further, we present evidence confirming a new indicine subgroup (I1a, 64 animals) mainly consisting of breeds originating from China and characterised by two private mutations within the I1 haplogroup. The total genetic variation was attributed mainly to within-breed variance (96.9%). The accuracy of the imputation of missing genotypes was high (99.8%) except for the relatively rare heteroplasmic genotypes, suggesting the potential for trait association studies within a breed.
LPJ-GMINT Documentation
Creators: name: Deborah Zani
Publisher: name: Zenodo
Year: 2024

description: Descriptive and technical documentation of the model LPJ-GMINT 1.0.

LPJ-GMINT 1.0 (LPJ-GUESS-MIGRATION-INTERACTION) couples a module for biotic interactions (INT module) to the vegetation global dynamic model (LPJ-GUESS algorithm), while allowing both plants and interacting species to migrate (migration module).

The documentation provides detailed descriptions of the implemented ecological processes and mathematical equations for the new INT module. A quick guide on the different MPI features and how to build and run the model is also provided.
Recovery of mitogenomes from whole genome sequences to infer maternal diversity in 1883 modern taurine and indicine cattle
Creators: name: Dorji, Jigme
name: Vander Jagt, CJ
name: Chamberlain, Amanda
name: Cocks, Benjamin
name: MacLeod, IM
name: Daetwyler, Hans
Publisher: name: La Trobe
Year: 2022

description: Maternal diversity based on a sub-region of mitochondrial genome or variants were commonly used to understand past demographic events in livestock. Additionally, there is growing evidence of direct association of mitochondrial genetic variants with a range of phenotypes. Therefore, this study used complete bovine mitogenomes from a large sequence database to explore the full spectrum of maternal diversity. Mitogenome diversity was evaluated among 1883 animals representing 156 globally important cattle breeds. Overall, the mitogenomes were diverse: presenting 11 major haplogroups, expanding to 1309 unique haplotypes, with nucleotide diversity 0.011 and haplotype diversity 0.999. A small proportion of African taurine (3.5%) and indicine (1.3%) haplogroups were found among the European taurine breeds and composites. The haplogrouping was largely consistent with the population structure derived from alternate clustering methods (e.g. PCA and hierarchical clustering). Further, we present evidence confirming a new indicine subgroup (I1a, 64 animals) mainly consisting of breeds originating from China and characterised by two private mutations within the I1 haplogroup. The total genetic variation was attributed mainly to within-breed variance (96.9%). The accuracy of the imputation of missing genotypes was high (99.8%) except for the relatively rare heteroplasmic genotypes, suggesting the potential for trait association studies within a breed.
Fibrin clot characteristics and anticoagulant response in a SARS‐CoV‐2‐infected endothelial model
Creators: name: McCafferty, Conor
name: Lee, Leo
name: Cai, Tengyi
name: Praporski, Slavica
name: Stolper, Julian
name: Karlaftis, Vasiliki
name: Attard, Chantal
name: Myint, David
name: Carey, Leeanne
name: Howells, David W
name: Donnan, Geoffrey A
name: Davis, Stephen
name: Ma, Henry
name: Crewther, Sheila
name: Nguyen, Vinh
name: Van Den Helm, Suelyn
name: Letunica, Natasha
name: Swaney, Ella
name: Elliott, David
name: Subbarao, Kanta
name: Ignjatovic, Vera
name: Monagle, Paul
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 3105
subject: Genetics
subject: FOS: Biological sciences
classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3201
subject: Cardiovascular medicine and haematology
classificationCode: 3207
subject: Medical microbiology

description: Coronavirus disease 2019 (COVID-19) patients have increased thrombosis risk. With increasing age, there is an increase in COVID-19 severity. Additionally, adults with a history of vasculopathy have the highest thrombotic risk in COVID-19. The mechanisms of these clinical differences in risk remain unclear. Human umbilical vein endothelial cells (HUVECs) were infected with SARS-CoV-2, influenza A/Singapore/6/86 (H1N1) or mock-infected prior to incubation with plasma from healthy children, healthy adults or vasculopathic adults. Fibrin on surface of cells was observed using scanning electron microscopy, and fibrin characteristics were quantified. This experiment was repeated in the presence of bivalirudin, defibrotide, low-molecular-weight-heparin (LMWH) and unfractionated heparin (UFH). Fibrin formed on SARS-CoV-2 infected HUVECs was densely packed and contained more fibrin compared to mock-infected cells. Fibrin generated from child plasma was the thicker than fibrin generated in vasculopathic adult plasma (p = 0.0165). Clot formation was inhibited by LMWH (0.5 U/ml) and UFH (0.1-0.7 U/ml). We show that in the context of the SARS-CoV-2 infection on an endothelial culture, plasma from vasculopathic adults produces fibrin clots with thinner fibrin, indicating that the plasma coagulation system may play a role in determining the thrombotic outcome of SARS-CoV-2 infection. Heparinoid anticoagulants were most effective at preventing clot formation.
Soil phosphorus sorption capacity dictates the effect of elevated CO2 on soil and plant critical phosphorus levels for wheat growth
Creators: name: O'Sullivan, James
name: Vongsouthi, Kevaly
name: Jin, Jian
name: Tang, Caixian
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 30
subject: Agricultural, veterinary and food sciences
classificationCode: 3002
subject: Agriculture, land and farm management
classificationCode: 3004
subject: Crop and pasture production
classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3108
subject: Plant biology
classificationCode: 4106
subject: Soil sciences

description: Background: Rising atmospheric CO2 concentrations can increase crop yields; however, it is poorly understood if plants require higher phosphorus (P) inputs to support increased production. In addition, soils with contrasting P-sorption capacities may alter plant response to elevated CO2. Aims: We examined the effect of elevated CO2 on the critical concentrations of soil available P and shoot P for plant growth in soils with contrasting P-sorption capacities. Methods: Response curves to P applications were generated for wheat (Triticum aestivum L.) grown in a low P-sorption Sodosol and a high P-sorption Ferrosol. Plants were grown for 5 weeks under ambient (400 ppm) and elevated (800 ppm) CO2 concentrations at nine P application rates. The concentrations of plant P and soil P extracted using Olsen, Bray and Resin methods were analysed. Results: Elevated CO2 increased biomass production in both soils. Plants grown in the Ferrosol but not in the Sodosol required higher P inputs to achieve maximum biomass production in response to elevated CO2. Elevated CO2 increased the critical Olsen-P but decreased the critical Bray-P concentrations for shoot biomass production in the Ferrosol. Elevated CO2 decreased the critical P concentration in shoots of plants grown in the Sodosol but not in the Ferrosol. Conclusions: The effect of P fertilisation on plant response to elevated CO2 depends on soil type. Elevated CO2 also potentially alters P acquisition mechanisms of plants, which requires adjustment of the critical P concentration in shoot and in soil depending on soil P-sorption capacity and the analytical method used to assess P availability.
BOSHLANG'ICH SINF O'QUVCHILARINING IJTIMOIY MUHITGA MOSLASHISHIDA BOG'CHA TARBIYASINING O'RNI.
Creators: name: Hamrayev, Ilg'or
name: Luqmonova, Madina
Publisher: name: Zenodo
Year: 2025

description: Ushbu maqolada boshlang‘ich sinf o‘quvchilarining ijtimoiy muhitga moslashuvi ularning maktab hayotiga muvaffaqiyatli integratsiyalashuvi va kelajakdagi ta’lim jarayonida muvaffaqiyat qozonishiga bevosita ta’sir ko‘rsatadi. Ushbu maqolada bolalar bog‘chasi tajribasining boshlang‘ich sinf o‘quvchilari uchun qanday muhum ahamiyatga ega ekani tahlil qilinadi. Maktabgacha ta’lim muassasalarida bola o‘z tengdoshlari bilan muloqot qilish, kattalar bilan munosabat o‘rnatish va ijtimoiy qoidalarga rioya qilishni o‘rganadi. Bu esa ularning kelajakda sinfdoshlari va o‘qituvchilar bilan samarali aloqa o‘rnatishi, dars jarayonida faol ishtirok etishi hamda jamoaviy muhitga tez moslashishiga yordam beradi.Tadqiqotlarda  maktabga qadam qo‘ygan  bolalarning yangi sharoitga moslashishida bog‘chada olingan bilim va ko‘nikmalarning ahamiyati, ijtimoiy muloqot malakalari va mustaqil faoliyat yuritish qobiliyatining rivojlanishiga ta’siri yoritiladi. Bundan tashqari, bog‘cha ta’limining bolaning hissiy – intellektual rivojlanishiga qo‘shadigan hissasi, uning kelajakdagi o‘quv jarayoniga ta’siri va adaptatsiya jaryonini yengillashtirishdagi roli muhokama qilingan.  Ushbu maqola ta’lim tizimining barcha Bo‘g‘inlari uchun foydali bo‘lib, bolalarning o‘quv jarayoniga ijtimoiy-psixologik moslashuvi masalalarini chuqur tushunishga yordam beradi
Draft Genome Sequences for Three Ophiostoma Species Acquired during Revisions of Australian Plant Pathogen Reference Collections
Creators: name: Trollip, Conrad
name: Carnegie, AJ
name: Rodoni, Brendan
name: Edwards, Jacqueline
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3105
subject: Genetics
classificationCode: 3107
subject: Microbiology

description: The fungal genus Ophiostoma contains numerous species that share close associations with wood-boring insects, a relationship with important consequences for global biosecurity. Here, we provide draft genomes for three Ophiostoma species within the well-known Ophiostoma ulmi complex. These resources are valuable for future research efforts related to Ophiostoma and the establishment of biosecurity-focused databases.
faezesarlakifar/AllerTrans: Version 1.0.0: AllerTrans Model Release
Creators: name: Faezeh Sarlakifar
Publisher: name: Zenodo
Year: 2024

description: The first release of AllerTrans, an Improved Protein Allergenicity Prediction Using Deep Learning,

This model is part of our non-profit research initiative to enhance protein allergenicity prediction in bioinformatics using deep neural network capabilities. We welcome feedback and collaboration from the research community.
Recent advances of aggregation-induced emission nanoparticles (AIE-NPs) in biomedical applications
Creators: name: Sabouri, Soheila
name: Yao, Bicheng
name: Hong, Yuning
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3206
subject: Medical biotechnology
subject: FOS: Medical biotechnology
classificationCode: 40
subject: Engineering

description: No description supplied
Donation receipts of the Tang On Company
Creators: name: Cheekungtong (Chinese Freemasons)
Publisher: name: The University of British Columbia
Year: 2015

description: Includes bound books of donation records from the Tang On Company for the Chinese Freemasons (Cheekungtong) that list the donors' names and donation amount. The donations might be for the operation of the Chinese Freemasons of Canada in Victoria, B.C. and for rendering financial assistance to members in need.
Correspondence, 1926-1934
Creators: name: MacDonell, Father Andrew
Publisher: name: The University of British Columbia
Year: 2015

description: Correspondence and other textual material relating to the settlement of Clandonald, including immigration forms, correspondence regarding planning of the settlement, memoranda of the Scottish Immigrant Aid Society, and James Brennand's report on the 16,000 acres of land in the Wainwright District of Alberta.
Bidirectional power flow in an electric vehicle using predictive control algorithm including sneak circuit analysis
Creators: name: Eti, Sri Latha
name: Sudha, Kasibhatla Rama
name: PankajLahari, Molleti Venkata
name: Sekhar, AkkapeddiChandra
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 400803
subject: Electrical energy generation (incl. renewables, excl. photovoltaics)

description: The use of electric vehicle battery chargers is becoming more common for transferring power between grid and energy storage system. This paper focuses on providing a comprehensive understanding of various modes of operation of these battery chargers. Two different controllers are used; one is the predictive power controller at the grid end to generate active and reactive power references to operate a 3-phase AC/DC converter connected between the power grid and the DClink and the other is a hysteresis current controller used to operate a reversible DC/DC converter connected between the DClink and electric vehicle battery and is considered as the main component of the energy storage system. Also, sneak circuit analysis is carried out on the DC/DC converter and the controller is designed accordingly. Results from simulations validate the suggested control scheme's viability and efficacy.The adopted topology is validated in real time with dSpace 1104 hardware in the loop prototype operating in different scenarios, both in steady-state and during transients.
Bidirectional power flow in an electric vehicle using predictive control algorithm including sneak circuit analysis
Creators: name: Journal, IJPEDS
name: Eti, Sri Latha
name: Sudha, Kasibhatla Rama
name: PankajLahari, Molleti Venkata
name: Sekhar, AkkapeddiChandra
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 400803
subject: Electrical energy generation (incl. renewables, excl. photovoltaics)

description: The use of electric vehicle battery chargers is becoming more common for transferring power between grid and energy storage system. This paper focuses on providing a comprehensive understanding of various modes of operation of these battery chargers. Two different controllers are used; one is the predictive power controller at the grid end to generate active and reactive power references to operate a 3-phase AC/DC converter connected between the power grid and the DClink and the other is a hysteresis current controller used to operate a reversible DC/DC converter connected between the DClink and electric vehicle battery and is considered as the main component of the energy storage system. Also, sneak circuit analysis is carried out on the DC/DC converter and the controller is designed accordingly. Results from simulations validate the suggested control scheme's viability and efficacy.The adopted topology is validated in real time with dSpace 1104 hardware in the loop prototype operating in different scenarios, both in steady-state and during transients.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Lee Shang Luey, Lim Gow, [Yip Dan], Lem Lai Bang, Yip Hong, Wong Hon, [Lew Fai], Leong Wah Suey, Lai Jack, Seto Ying.
La perception des dimensions du risque et l'intention entrepreneuriale : une application aux Jeunes Diplômés en Côte d'Ivoire
Creators: name: OUATTARA, Collè Soumaïla
name: FOFANA, Elie
name: KOFFI, Kouakou Bernard
Publisher: name: Zenodo
Year: 2024
Subjects: Entrepreneuriat ; Perception du Risque ; Intention ; Intention Entrepreneuriale ; Jeune Diplômé

description: Cet article tente d’étudier le lien entre la perception du risque et l’intention entrepreneuriale des jeunes diplômés Ivoiriens. Il explore la manière dont la perception du risque influence l’intention entrepreneuriale des jeunes diplômés Ivoiriens. Notre recherche repose sur une méthodologie mixte. La phase qualitative a consisté à réaliser des entretiens semi-directifs auprès des étudiants ivoiriens. Cette phase qualitative nous a permis de valider nos concepts et adapter les échelles de mesure. Par la suite, une étude quantitative a été menée auprès de ceux-ci. Les résultats issus de nos analyses soulignent que le risque personnel et le risque financier influencent l’intention entrepreneuriale. Quant à la variable « risque social», les résultats montrent qu’elle n’explique pas l’intention entrepreneuriale. Ces résultats semblent apporter des solutions aux problèmes liés à la réduction du taux de chômage.
Molecular basis of Tick Born encephalitis virus NS5 mediated subversion of apico-basal cell polarity signalling
Creators: name: Javorsky, Airah Joyce
name: Humbert, Patrick
name: Kvansakul, Marc
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology

description: The Scribble (Scrib) protein is a conserved cell polarity regulator with anti-tumorigenic properties. Viruses like the Tick-born encephalitis virus (TBEV) target Scribble to establish a cellular environment supporting viral replication, which is ultimately associated with poor prognosis upon infection. The TBEV NS5 protein has been reported to harbour both an internal as well as a C-terminal PDZ binding motif (PBM), however only the internal PBM was shown to be an interactor with Scribble, with the interaction being mediated via the Scribble PDZ4 domain to antagonize host interferon responses. We examined the NS5 PBM motif interactions with all Scribble PDZ domains using isothermal titration calorimetry, which revealed that the proposed internal PBM did not interact with any Scribble PDZ domains. Instead, the C-terminal PBM of NS5 interacted with Scrib PDZ3. We then established the structural basis of these interactions by determining crystal structures of Scrib PDZ3 bound to the NS5 C-terminal PBM. Our findings provide a structural basis for Scribble PDZ domain and TBEV NS5 interactions and provide a platform to dissect the pathogenesis of TBEV and the role of cell polarity signalling using structure guided approaches.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Chan Kwong Chen, Chan Hee Mon, Chan King Guey, Chan Chen Won, Yip Mon, Harold Chin, Lee Bark Chong, Lum Lin, Eng Chow Woo, [Lee Sing Fon].
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Mah Shong, Lim Hong Chong, Chew Fong, Lum Him, [Cheung Bing Jong], Lew Kai Foon, Chan Leong Fong, Wong On, Tsang Hong Bing, Chan Saw.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Jung Goom Joon, Goom Jong Wee, Woo Joon Fai, Wong Fook Luon, Jung How Wai, Lew Mon Won, Mrs. Chew Woo, Chong Sing, Woo Gim Hong, Loy Low.
‘I’m not going anywhere near that': Expert stakeholder challenges in working with boys and young men regarding sex and sexual consent
Creators: name: Waling, Andrea
name: James, Alexandra
name: Fairchild, Jack
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 44
subject: Human society
classificationCode: 4405
subject: Gender studies
classificationCode: 4407
subject: Policy and administration
classificationCode: 4409
subject: Social work
classificationCode: 4410
subject: Sociology
subject: FOS: Sociology

description: No description supplied
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Lam Pon, Wong Lai Fong, lai lap Gee, lai Duck Kin, Chan Jack Why, Wong Lai Ming, [Lore Yung Sung], Cham Kwock Leong, Wong Guey Dan.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Mah Sing, Soo Gang, Won Yiok, [Fong Yok], Huey Chung, Joy Nam, Joye Joe, Jang Gin On, Low Gim Yoke, Kwan Wing Kwock.
Perceived extrinsic barriers hinder community detection and management of mild cognitive impairment: a cross-sectional study of general practitioners in Shanghai, China
Creators: name: Lu, Yuan
name: Liu, Chaojie
name: Fawkes, Sally
name: Wang, Z
name: Yu, D
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 3202
subject: Clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems
classificationCode: 4206
subject: Public health

description: Background: General practitioners (GPs) play a critical role in community detection and management of mild cognitive impairment (MCI). Although adequate knowledge is essential, healthcare practice is shaped by intrinsic and extrinsic factors. This study aimed to test the mediating effect of perceived extrinsic barriers on the associations between knowledge, attitudes, and intended practice of GPs in community detection and management of MCI. Methods: A cross-sectional study was conducted through an online survey of 1253 GPs sampled from 56 community health centres (CHCs) in Shanghai in 2021. Perceived extrinsic barriers were rated on a five-point Likert scale for patient engagement, working environment, and system context, respectively. A summed score was generated subsequently for each domain ranging from 0 to 100, with a higher score indicating higher barriers. The mediating effect of perceived extrinsic barriers (second-order) and the moderation effect of training on the association between MCI knowledge and practice scores, as well as the moderation effect of past experience on the association between MCI knowledge and extrinsic barriers, were tested through structural equation modelling (SEM) with a partial least square (PLS) approach. Results: The study participants reported an average barrier score of 65.23 (SD = 13.98), 58.34 (SD = 16.95), and 60.37 (SD = 16.99) for patient engagement, working environment, and system context, respectively. Although knowledge had both direct and indirect (through attitudes) effects on intended practice, perceived extrinsic barriers negatively mediated (β = − 0.012, p = 0.025) the association between knowledge and practice. Training moderated the effect of knowledge on practice (β = − 0.066, p = 0.014). Conclusions: Perceived extrinsic barriers have a detrimental effect on the translation of knowledge into practice for community detection and management of MCI. The effect of training on practice declines when knowledge scores become higher.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: [Dair Jung], Mrs. Lee King, Chung Fat Shu, lee Poo Sing, Chee Sam, Lee Yem, Chin Len Jai, Lew Ho, Wong Fee, Lam Wing.
Insectolaelaps Shcherbak 1980
Creators: name: Mašán, Peter
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Digamasellidae
Insectolaelaps

description: Insectolaelaps Shcherbak, 1980
Insectolaelaps Shcherbak, 1980: 192.
Type species: Dendrolaelaps armatus Hirschmann, 1960, by original designation (only armatus group).
Dendrolaelaps (Insectolaelaps).— Hirschmann & Wiśniewski, 1982: 31.
Insectolaelaps.— Karg, 1993: 368.
non Dendrolaelaps (Ipidodendrolaelaps) Hirschmann & Wiśniewski, 1982: 38. Synonymy by Karg, 1993: 368.
Taxonomic notes
The genus Insectolaelaps is a rather small group of digamasellid mites distributed in the Holarctic, currently comprising 15 known species from Europe (10 spp.), Asia (3 spp.) and North America (2 spp.), mainly found in saproxylic habitats, especially in subcortical spaces associated with galleries of bark- and wood-boring beetles. The phoretic activity of their deutonymphs is common in many xylophagous beetles, especially in the scolytine curculionids (Hirschmann and Wiśniewski 1982).
Insectolaelaps was originally described by Shcherbak (1980) as a genus of Rhodacaridae Oudemans and later treated as a subgenus of Dendrolaelaps Halbert by Hirschmann & Wiśniewski (1982). Karg (1993) and Castilho (2012) considered Insectolaelaps as a separate genus of Dendrolaelapinae Hirschmann and Digamasellidae Evans, respectively (both as equivalent taxa), with Ipidodendrolaelaps Hirschmann & Wiśniewski as a conspecific taxon, whose species were also included in the genus by Shcherbak (1980), as species of the quadrisetus group sensu Lindquist, 1975. In my opinion, the separate position of Ipidodendrolaelaps, including the four species known from the Holarctic (Castilho 2012), is justified and should be considered a valid taxon in future taxonomic revisions.
The original description of the genus by Shcherbak (1980) does not need to be fundamentally changed here, with the exception of the specific chaetotaxy of genu III. Thus, the concept of Insectolaelaps used here is mainly based on the following character states: (1) sperm induction system of females with highly modified genital structures shaped as small and paired spherical organs, usually bearing short hyaline appendages (tubuli annulati, sacculus foemineus or tubes in proximal leg segments absent); (2) female genital structures associated with coxae IV; (3) movable digit of chelicerae with at least five teeth in females; (4) genu III with only one ventral seta (pv1 absent); (5) posterior row of denticles distinctly wider than preceding rows, all rows with many denticles; (6) legs IV spurred in males [except in Insectolaelaps zvoleniensis (Wiśniewski & Hirschmann)]; (7) all podonotal setae on shield surface in adults.
description: Published as part of Mašán, Peter, 2025, Digamasellid mites (Acari: Mesostigmata) in association with saproxylic darkling beetles (Coleoptera: Tenebrionidae) and wood-decaying fungi (Polyporales) in Slovakia, pp. 1-58 in Zootaxa 5627 (1) on page 8, DOI: 10.11646/zootaxa.5627.1.1, http://zenodo.org/record/15325037
New hominin dental remains from the Drimolen Main Quarry, South Africa (1999–2008)
Creators: name: Leece, Angeline
name: Martin, Jess
name: Herries, Andrew
name: Riga, A
name: Menter, CG
name: Moggi-Cecchi, J
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 43
subject: History, heritage and archaeology
classificationCode: 4301
subject: Archaeology
classificationCode: 44
subject: Human society
classificationCode: 4401
subject: Anthropology
subject: FOS: Sociology

description: Objectives: Twenty-four dental specimens from the Drimolen Main Quarry (DMQ) are described. This increases the number of DMQ Paranthropus robustus specimens from 48 to 63 and DMQ Homo specimens from 8 to 12. This allows reassessment of the proposed differences between the DMQ P. robustus assemblage and that of Swartkrans. Analysis conducted assesses intraspecific and inter-locality variation. Materials and Methods: We examined the P. robustus and early Homo assemblages from South Africa. Morphology was observed using a hand lens and a binocular microscope. Mesiodistal and buccolingual measurements were taken using plastic-tipped calipers. Summary statistics were generated and patterns of variability in P. robustus were assessed through box plots and Mann–Whitney U tests. Results: Comparison between the expanded DMQ and Swartkrans P. robustus assemblages demonstrates overlap in size. Ten dental variables show statistically significant differences. Discussion: The expanded P. robustus sample allowed us to re-examine previous analyses of differences in tooth size between the samples. While analyses presented here show a high degree of overlap in the MD and BL dimensions of the two assemblages, significant differences were found in the mean values of these variables in the postcanine maxillary teeth—consistent with previous analyses. Two current hypotheses may explain this pattern: 1) dental size increase through the P. robustus lineage or 2) different sample composition between the two sites. Small sample sizes for all permanent dental classes in the DMQ assemblage represents a limitation on this analysis and interpretations thereof. Any addition to the DMQ or the Swartkrans samples may alter these results.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Wong Jing Chung, Lee Wan, Lee Sheck, Lee Chung Yone, Lee Wing Kai, Seto Yet Mon, Wong Shee Hing, [Soon Jai Gum], Lee Luing Yee, Mah Gim Chew.
Supplementary document for Refraction beats attenuation in breast CT - 6428381.pdf
Creators: name: Rawlik, Michal
name: Pereira, Alexandre
name: Spindler, Simon
name: Wang, Zhentian
name: Romano, Lucia
name: Jefimovs, Konstantins
name: Shi, Zhitian
name: Polikarpov, Maxim
name: xu, jinqiu
name: Zdora, Marie
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
Cosmic dance in the Shapley Concentration Core II. The uGMRT-MeerKAT view of filaments in the brightest cluster galaxies and tailed radio galaxies in the A3528 cluster complex
Creators: name: Di Gennaro, Gabriella
Publisher: name: Zenodo
Year: 2024

description: This document contains the Appendix to the paper "Cosmic dance in the Shapley Concentration Core II. The uGMRT-MeerKAT view of filaments in the brightest cluster galaxies and tailed radio galaxies in the A3528 cluster complex" published on Astronomy & Astrophysics (arxiv:2408.14142)
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Chee Soo, Wong See Gong, Fong Sing, Fong Hon, Lew Lai Kee, [Wong Wing Suck], [Wen Wing Hong], Chow Fong Fun, Won Fong Jung, Won Goey Hing.