cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Was ist eigentlich dieses Forschungsdatenmanagement? Ansätze zur bedarfsorientierten Modellierung des Managements von Forschungsdaten
Creators: name: Helling, Patrick
Publisher: name: Zenodo
Year: 2022
Subjects: SaxFDM-Tagung
Vortrag

description: Mit diesem Beitrag sollen Ansätze zur Entwicklung eines formalen Beschreibungsmodells von FDM-Bedarfen unter Berücksichtigung der Perspektive von Forschenden am Beispiel des Data Center for the Humanities (DCH) an der Universität zu Köln vorgestellt und dis­kutiert werden. Das DCH ist als fachspezifisches Datenzentrum für die Geisteswissenschaften für die Beratung und aktive Unter­stützung von Forschenden der Philosophischen Fakultät bei Fra­gen zum Umgang mit Forschungsdaten verantwortlich (Blumtritt et al. 2018). Es verfügt über einen formalisierten Beratungsser­vice (Helling et al. 2018b) sowie ein umfassendes fachspezifisches Service-Portfolio. Jedes FDM-Beratungsgespräch wird durch die Mitarbeiter*innen des DCH in Form von semi-strukturierten Bera­tungsprotokollen dokumentiert. Diese Protokolle stellten in ano­nymisierter Form bereits die Basis für eine qualitative Inhaltsanalyse tatsächlicher FDM-Bedarfe dar, die an das Datenzentrum her­angetragen werden: Durch eine deduktive Kategorienbildung im Sinne einer zusammenfassenden Inhaltsanalyse nach Mayring (2015) konnten mittlerweile bereits 45 individuelle FDM-Bedarfs­kategorien identifiziert werden. Beratungsprotokolle mit identi­schen FDM-Bedarfskategorien wurden schließlich geclustert. Im Anschluss wurden innerhalb dieser Cluster Informationen, die die jeweilige FDM-Bedarfskategorie beschreiben bzw. beeinflussen identifiziert und formal kategorisiert, um schließlich eine formale Beschreibung der FDM-Bedarfskategorie zu entwickeln (Helling 2022 i.E.). Gleichzeitig wurden innerhalb der Cluster dokumen­tierte Workflows zur Bedienung eines FDM-Bedarfs identifiziert. Durch ein Mapping verschiedener Workflows innerhalb eines Clus­ters konnten prototypische Workflows zur Bedienung von konkreten FDM-Bedarfskategorien abgeleitet werden (Helling 2020).
User-Conditioned Neural Control Policies for Mobile Robotics
Creators: name: Bauersfeld, Leonard
name: Kaufmann, Elia
name: Scaramuzza, Davide
Publisher: name: arXiv
Year: 2022
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Recently, learning-based controllers have been shown to push mobile robotic systems to their limits and provide the robustness needed for many real-world applications. However, only classical optimization-based control frameworks offer the inherent flexibility to be dynamically adjusted during execution by, for example, setting target speeds or actuator limits. We present a framework to overcome this shortcoming of neural controllers by conditioning them on an auxiliary input. This advance is enabled by including a feature-wise linear modulation layer (FiLM). We use model-free reinforcement-learning to train quadrotor control policies for the task of navigating through a sequence of waypoints in minimum time. By conditioning the policy on the maximum available thrust or the viewing direction relative to the next waypoint, a user can regulate the aggressiveness of the quadrotor's flight during deployment. We demonstrate in simulation and in real-world experiments that a single control policy can achieve close to time-optimal flight performance across the entire performance envelope of the robot, reaching up to 60 km/h and 4.5g in acceleration. The ability to guide a learned controller during task execution has implications beyond agile quadrotor flight, as conditioning the control policy on human intent helps safely bringing learning based systems out of the well-defined laboratory environment into the wild.
description: 6 pages + 1 pages references
Uønsket seksuel opmærksomhed (USO) fra ledere og kollegaer
Creators: Det Nationale forskningscenter for Arbejdsmiljø(NFA)
Ida E. H. Madsen
Publisher: name: Rigsarkivet
Year: 2023

description: Formålet med projektet er at udvikle redskaber,som skal hjælpe arbejdspladserne med og håndtere USO fra ledere og kollegaer gennemen systematisk og organisatorisk indsats.Projektetomfatter:
· Et valideret monitoreringsredskab, som bidrager med mere nuanceret viden om USO fraledere og kollegaer· En vejledning (udarbejdet i samarbejde medudvalgte arbejdspladser) til ledere,arbejdsmiljørepræsentanter (AMR) ogtillidsrepræsentanter (TR), som skal bidrage til en systematisk og organisatorisk indsats · Et dialogspil til ledere og medarbejdere, somskal hjælpe med at italesætte USO · Business-cases, som bidrager med viden om økonomiske omkostninger og mulige besparelser ved en systematisk og organisatorisk indsats· Viden om konsekvenserne for de berørte medarbejdere og konkrete eksempler på USO.
A Scaling Law to Predict the Finite-Length Performance of Spatially-Coupled LDPC Codes
Creators: name: Olmos, Pablo M.
name: Urbanke, Rüdiger
Publisher: name: arXiv
Year: 2014
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: Spatially-coupled LDPC codes are known to have excellent asymptotic properties. Much less is known regarding their finite-length performance. We propose a scaling law to predict the error probability of finite-length spatially-coupled ensembles when transmission takes place over the binary erasure channel. We discuss how the parameters of the scaling law are connected to fundamental quantities appearing in the asymptotic analysis of these ensembles and we verify that the predictions of the scaling law fit well to the data derived from simulations over a wide range of parameters. The ultimate goal of this line of research is to develop analytic tools for the design of spatially-coupled LDPC codes under practical constraints.
Moments and oscillations of exponential sums related to cusp forms
Creators: name: Vesalainen, Esa V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: We consider large values of long linear exponential sums involving Fourier coefficients of holomorphic cusp forms. The sums we consider involve rational linear twists $e(nh/k)$ with sufficiently small denominators. We prove both pointwise upper bounds and bounds for the frequency of large values. In particular, the $k$-aspect is treated. As an application we obtain upper bounds for all the moments of the sums in question. We also give the asymptotics with the right main term for fourth moments. We also consider the mean square of very short sums, proving that on average short linear sums with rational additive twists exhibit square root cancellation. This result is also proved in a slightly sharper form. Finally, the consideration of moment estimates for both long and short exponential sums culminates in a result concerning the oscillation of the long linear sums. Essentially, this result says that for a positive proportion of time, such a sum stays in fairly long intervals, where its order of magnitude does not drop below the average order of magnitude and where its argument is in a given interval of length $3π/2+\varepsilon$ and so can not wind around the origin.
Anomaly-free cosmological perturbations in effective canonical quantum gravity
Creators: name: Barrau, Aurelien
name: Bojowald, Martin
name: Calcagni, Gianluca
name: Grain, Julien
name: Kagan, Mikhail
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: This article lays out a complete framework for an effective theory of cosmological perturbations with corrections from canonical quantum gravity. Since several examples exist for quantum-gravity effects that change the structure of space-time, the classical perturbative treatment must be rethought carefully. The present discussion provides a unified picture of several previous works, together with new treatments of higher-order perturbations and the specification of initial states.
description: 1+52 pages. v2: discussions extended and improved throughout the text, references added, typos corrected, conclusions unchanged
Enantioselective Hydrosilylation and Hydrogenation of Alkaloid Precursors
Creators: name: Brunner, H.
name: Kürzinger, A.
name: Mahboobi, Siavosh
name: Wiegrebe, Wolfgang
Publisher: name: Universität Regensburg
Year: 1988
Subjects: subject: 540 Chemie

description: Enantioselective hydrosilylations of the 3,4-dihydropyrrole derivatives 1a-c and 5 with in-situ catalysts consisting of [Rh(cod)Cl]2 and optically active phosphines yield the N-silyl compounds 2a-c and 6 in up to 66.1 % ee. The N-silyl derivatives were treated with acetic formic anhydride or trifluoroacetic anhydride to give the N-formyl and N-trifluoroacetyl compounds 3a-c, 4a-c, 7, and 8. The alkaloids nicotine and macrostomine were synthesized with 63.3 and 33 % ee by reduction of the N-formyl compounds 8 and 12. Enantioselective hydrogenations of the N-formyl and N-trifluoroacetyl-2-phenylpyrrolines 14 and 15 with the same in-situ catalysts produce the cyclic amides 3a and 4a in up to 36.1 % ee. Die enantioselektive Hydrosilylierung der 3,4-Dihydropyrrol-Derivate 1a-c, 5 mit in-situ-Katalysatoren bestehend aus [Rh(cod)Cl]2 und optisch aktiven Phosphinen ergab die N-Silylverbindungen 2a-c, 6 in bis zu 66.1 % ee. Die N-Silyl-Derivate wurden mit Acetylformylanhydrid bzw. Trifluoracetanhydrid versetzt, wobei die N-Formyl- und N-Trifluoracetyl- Verbindungen 3a-c, 4a-c, 7 und 8 gebildet wurden. Die Alkaloide Nicotin und Macrostomin wurden mit 63.3 und 33 % ee durch Reduktion der N-Formyl-Verbindungen 8 und 12 synthetisiert. Die enantioselektive Hydrierung der N-Formyl- und N-Trifluoracetyl-2-phenylpyrroline 14 und 15 mit denselben in-situ-Katalysatoren ergab die cyclischen Amide 3a, 4a mit bis zu 36.1 % ee.
Gauged Hamiltonian Floer homology I: definition of the Floer homology groups
Creators: name: Xu, Guangbo
Publisher: name: arXiv
Year: 2013
Subjects: subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics
subject: 54D40, 53D20

description: We construct the vortex Floer homology group $VHF (M,μ;H)$ for an aspherical Hamiltonian $G$-manifold $(M, ω)$ with moment map $μ$ and a class of $G$-invariant Hamiltonian loop $H_t$, following the proposal of [3]. This is a substitute for the ordinary Hamiltonian Floer homology of the symplectic quotient of $M$. We achieve the transversality of the moduli space by the classical perturbation argument instead of the virtual technique, so the homology can be defined over ${\mathbb Z}$ or ${\mathbb Z}_2$.
description: v2. 48 pages, submitted version, corrected a mistake in the first arXiv version pointed by Woodward. v1. 47 pages
Connective constant for a weighted self-avoiding walk on $\mathbb{Z}^2$
Creators: name: Glazman, Alexander
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 82B41

description: We consider a self-avoiding walk on the dual $\mathbb{Z}^2$ lattice. This walk can traverse the same square twice but cannot cross the same edge more than once. The weight of each square visited by the walk depends on the way the walk passes through it and the weight of the whole walk is calculated as a product of these weights. We consider a family of critical weights parametrized by angle $θ\in[\fracπ{3},\frac{2π}{3}]$. For $θ=\fracπ{3}$, this can be mapped to the self-avoiding walk on the honeycomb lattice. The connective constant in this case was proved to be equal to $\sqrt{2+\sqrt{2}}$ by Duminil-Copin and Smirnov in \cite{DS10}. We generalize their result.
description: 13 pages, 5 figures
Dithranol, Active Oxygen Species and Lipid Peroxidation in vivo
Creators: name: Müller, K.
name: Wiegrebe, Wolfgang
name: Younes, Maged
Publisher: name: Universität Regensburg
Year: 1987
Subjects: subject: 540 Chemie

description: At pH 7.8 the dithranol anion 1a is oxidized in the dark to yield the bianthrone 3 besides dithranol brown, whilst 02 is reduced to 02.- and H202. 02.- was detected by the reduction of nitroblue-tetrazolium (NBT, 4). The formation of the formazan 5 was inhibited by superoxide dismutase (SOD). Exclusion of 02 and addition of SOD reveal a direct electron transfer from 1a to 4 and to cytochrome c which was not affected in the presence of SOD. - In vivo experiments indicate a low rate of lipid peroxidation which was determined on the basis of ethane exhalation. Dithranolanion (1a) wird bei pH 7.8 unter Lichtausschluß zum Bianthron 3 und zu Dithranolbraun oxidiert, während 02 zu 02.- und H202 reduziert wird. 02.- wurde durch Reduktion von Nitrotetrazoliumblau (NBT, 4) nachgewiesen, die Bildung des Formazans 5 wurde durch Superoxid Dismutase (SOD) gehemmt. 02-Ausschluß und Zugabe von SOD weisen einen direkten Elektronentransfer von la auf 4 bzw. Cytochrom c nach, der in Gegenwart von SOD nicht beeinträchtigt wurde. - In vivo-Experimente weisen auf eine geringfügige Lipidperoxidation hin, die über die Ethanausatmung gemessen wurde.
Analysis of discrete dynamical systems: An algebraic perspective
Creators: name: Porreca, Antonio E.
Publisher: name: Zenodo
Year: 2022

description: We consider (finite, discrete-time) dynamical systems in the most general sense, as a finite sets of states with a (deterministic) transition to the next state. As such, dynamical systems can be used for modelling phenomena or devices (e.g., physical or software) of scientific or engineering interest. It is often necessary to detect interesting behaviour in such systems, such as stable or repeated behaviour, sensitivity with respect to the initial conditions, or reversibility. However, it is often convenient to first decompose larger systems into smaller ones, easier to analyse separately, and then deduce the overall behaviour from that of these components. We will consider one among several possible approaches to this task, where each system is obtained from smaller ones by two appropriate algebraic operations of sum and product (alternate and synchronous execution, respectively), and investigate questions such as the solvability of equations involving these operations and the existence of prime elements (basic building blocks necessary in order to construct arbitrary larger systems).
description: Video conference talk at the CoCo seminar, Center for Collective Dynamics of Complex Systems at Binghamton University, USA, 26 October 2022 [https://coco.binghamton.edu/seminar-fall2022.html]. A video of the talk is available at https://vimeo.com/764253257.
$R$-boundedness versus $γ$-boundedness
Creators: name: Kwapień, Stanislaw
name: Veraar, Mark
name: Weis, Lutz
Publisher: name: arXiv
Year: 2014
Subjects: subject: Functional Analysis (math.FA)
subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 47B99 (Primary), 46B09, 46B07, 47B10 (Secondary)

description: It is well-known that in Banach spaces with finite cotype, the $R$-bounded and $γ$-bounded families of operators coincide. If in addition $X$ is a Banach lattice, then these notions can be expressed as square function estimates. It is also clear that $R$-boundedness implies $γ$-boundedness. In this note we show that all other possible inclusions fail. Furthermore, we will prove that $R$-boundedness is stable under taking adjoints if and only if the underlying space is $K$-convex.
description: Accepted for publication in Arkiv f\"or Matematik
Accelereret digital transformation i universitetssektoren: En reaktion på COVID-19
Creators: Aalborg Universitet Institut for Politik ogSamfund Center for IT Ledelse
Jeppe Agger Nielsen
Publisher: name: Rigsarkivet
Year: 2023

description: The Covid-19 emergency paves the way for accelerated innovation & change esp. in the university sector which is currently being transformed into an experiment in online teaching. The situation constitutes an extreme case that can elucidate digital transformation as part of a crisis management situation that requires immediate response from all organizational levels. Our case is the Faculty of Social Sciences, which has turned 100% digital in the wake of Covid-19, and thus provides a unique opportunity to study digital transformation in real time and follow up on the longterm impacts of the transformation. Qualitative & quantitative data will be used to examine the accelerated digital transformation of university teaching activities. This project contributes to extant digital transformation literature with new empirical insights as well as theorizing about the management of immediate response-ability and subsequent sustain-ability of accelerated digital transformation in a crisis.
Categories in Control
Creators: name: Baez, John C.
name: Erbele, Jason
Publisher: name: arXiv
Year: 2014
Subjects: subject: Category Theory (math.CT)
subject: Quantum Algebra (math.QA)
subject: Quantum Physics (quant-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: Control theory uses "signal-flow diagrams" to describe processes where real-valued functions of time are added, multiplied by scalars, differentiated and integrated, duplicated and deleted. These diagrams can be seen as string diagrams for the symmetric monoidal category FinVect_k of finite-dimensional vector spaces over the field of rational functions k = R(s), where the variable s acts as differentiation and the monoidal structure is direct sum rather than the usual tensor product of vector spaces. For any field k we give a presentation of FinVect_k in terms of the generators used in signal flow diagrams. A broader class of signal-flow diagrams also includes "caps" and "cups" to model feedback. We show these diagrams can be seen as string diagrams for the symmetric monoidal category FinRel_k, where objects are still finite-dimensional vector spaces but the morphisms are linear relations. We also give a presentation for FinRel_k. The relations say, among other things, that the 1-dimensional vector space k has two special commutative dagger-Frobenius structures, such that the multiplication and unit of either one and the comultiplication and counit of the other fit together to form a bimonoid. This sort of structure, but with tensor product replacing direct sum, is familiar from the "ZX-calculus" obeyed by a finite-dimensional Hilbert space with two mutually unbiased bases.
description: 42 pages LaTeX
Long-range interactions of aromatic molecules with alkali-metal and alkaline-earth-metal atoms
Creators: name: Shirkov, Leonid
name: Tomza, Michał
Publisher: name: arXiv
Year: 2022
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: The isotropic and anisotropic coefficients $C^{l,m}_n$ of the long-range spherical expansion $\sim 1/R^n$ ($R$ -- the intermolecular distance) of the dispersion and inductions intermolecular energies are calculated using the first principles for the complexes containing an aromatic molecule (benzene, pyridine, furan, and pyrrole) and alkali-metal (Li, Na, K, Rb, and Cs) or alkaline-earth-metal (Be, Mg, Ca, Sr, and Ba) atoms in their electronic ground states. The values of the first and second-order properties of the aromatic molecules are calculated using the response theory with the asymptotically corrected LPBE0 functional. The second-order properties of the closed-shell alkaline-earth-metal atoms are obtained using the expectation-value coupled cluster theory and of the open-shell alkali-metal atoms using analytical wavefunctions. These properties are used for the calculation of the dispersion $C^{l,m}_{n,\text{disp}}$ and induction $C^{l,m}_{n,\text{ind}}$ coefficients ($C^{l,m}_n=C^{l,m}_{n,\text{disp}}+C^{l,m}_{n,\text{ind}}$) with $n$ up to 12 using the available implemented analytical formulas. It is shown that the inclusion of the coefficients with $n>6$ is important for reproducing the interaction energy in the van der Waals region at $R\approx 6$ angstrom. The reported long-range potentials should be useful for constructing the analytical potentials, valid for the whole intermolecular interaction range, which are needed for spectroscopic and scattering studies.
description: 9 pages, 2 figures, 4 tables
Datenbank oder Datensätze – Zwei verschiedene Sichtweisen auf Forschungsdatenmanagement und ihre Auswirkungen
Creators: name: Meigen, Christof
Publisher: name: Zenodo
Year: 2022
Subjects: SaxFDM-Tagung
Vortrag

description: Alle funktionierenden IT-Strukturen großer Studien gleichen einan­der: Es gibt ein Kontaktmanagement, eine Studiendatenbank, Gerä­tedaten (oft mit speziellen Lösungen für Bild- und OMICS-Daten) und eine Forschungsdatenbank. Die Ausgangspunkte – sowohl konzepti­onell als auch in der zeitlichen Entwicklung der Projekte – sind jedoch oft verschieden. Basierend auf jeweils einem halben Jahrzehnt Erfah­rung in zwei großen Studien werden zwei gegensätzliche technische Sichtweisen und ihre Implikationen vorgestellt: • Aus der einen Sicht gibt es viele – relativ unabhängig agierende – Quellsysteme, in denen Originaldaten dauerhaft verwaltet wer­den. Die Aufgabe des Forschungsdatenmanagements besteht im wesentlichen in der nachträglichen Zusammenführung der Daten für die Forschungdatenbank. • Aus der anderen Sicht dienen Quellsysteme lediglich der Daten­erfassung, und nicht der dauer- haften Verwaltung erhobener Daten – diese werden bei oder direkt nach Erhebung in wenigen zentralen, eng vernetzten Datenbanken verarbeitet. Ausgehend von beiden Ansätzen können jeweils robuste Lösungen für die üblichen Anforderungen im Forschungsbereich erstellt wer­den. Die Details – beispielsweise bei Datenkuration, Rohdaten- Archi­vierung, ID-Managment, Verwaltung von Metadaten oder Umgang mit Fehlwerten sind jedoch strukturbedingt grundverschieden. Dies bedeutet auch, dass bestimmte Anforderungen in den verschiede­nen Ansätzen zur Verwunderung Aussenstehender einen deutlich verschiedenen Aufwand bei der Umsetzung erfordern. In dem Vor­trag wird zur Einführung die Infrastruktur von LIFE Child (Universität Leipzig) und der Rheinland Studie (DZNE Bonn) kurz vorgestellt. Bei­des sind auf Jahrzehnte angelegte große epidemiologische Studien, an denen der Vortragende in leitender IT-Funktion beteiligt war bzw. ist. Bezugnehmend auf strukturelle Unterschiede wird anhand vieler konkreter praktischer Beispiele demonstriert, welche Herausfor­derungen spezifische Wünsche von Studienmitarbeiter:innen sowie Einhaltung von FAIR-Prinzipien und guter wissenschaftlicher Praxis für die jeweiligen Ansätze bedeuten. Wer also immer schon wissen wollte, warum einige Datenmanager bei Begriffen wie Audit-Trail Schweißausbrüche bekommen während andere mit den Schultern zucken, was Prüfsummen mit referenzieller Integrität zu tun haben, warum einige Forschungsdatensätze täglich und andere vierteljähr­lich erstellt werden und wie man eine Studie durchführt ohne dass jemals irgendjemand die Studienkennung eines Teilnehmers sieht ist herzlich eingeladen zu dieser Tour durch die Spiegelwelten zweier Systeme.
Die Zukunft ist digital
Creators: name: Ball, Rafael
Publisher: name: Universität Regensburg
Year: 2010
Subjects: subject: 020 Bibliotheks- und Informationswissenschaft

description: Unter dem Titel "Wege in die Zukunft - Chancen der Digitalisierung" veranstaltete der verband der Deutschen Fachpresse am 18. und 19. Mai 2010 in Wiesbaden seinen jährlichen Fachkongress.
On The Special Curves In Minkowski 4 Spacetime
Creators: name: Güner, Gül
name: Ekmekci, Nejat
Publisher: name: arXiv
Year: 2014
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: In [1], we gave a method for constructing Bertrand curves from the spherical curves in 3 dimensional Minkowski space. In this work, we construct the Bertrand curves corresponding to a spacelike geodesic and a null helix in Minkowski 4 spacetime.
International Social Survey Programme 2018 - Religion IV
Creators: Institut for Politik og Samfund, Aalborg Universitet
Sanne Lund Clement
Publisher: name: Rigsarkivet
Year: 2023

description: Formålet er at indsamle de danske data til ISSP-undersøgelsen 2018, der handlede om danskernes forhold til religion. ISSP er et netværk af mere end 40 lande, der årligt gennemfører en større, tværnational holdningsundersøgelse med varierende tema.
Cardiovascular effects of modulators of soluble guanylyl cyclase activity.
Creators: name: Hoenicka, Markus
name: Schmid, Christof
Publisher: name: Universität Regensburg
Year: 2008
Subjects: subject: 610 Medizin
subject: Animals
subject: Atherosclerosis/etiology
subject: Carbon Monoxide/physiology
subject: Cardiovascular Agents/pharmacology
subject: Cyclic GMP/physiology
subject: Guanylate Cyclase/physiology
subject: Humans
subject: Hypertension/etiology
subject: Hypertension, Pulmonary/etiology
subject: Nitric Oxide/physiology
subject: Nitric Oxide Donors/pharmacology
subject: Signal Transduction

description: Soluble guanylyl cyclase (sGC) is one of the key enzymes of the nitric-oxide (NO)/cyclic 3',5'-guanosine monophosphate (cGMP) pathway. Located in virtually all mammalian cells, it controls the vessel tone, smooth muscle cell growth, platelet aggregation, and leukocyte adhesion. In vivo sGC activity is mainly regulated by NO which in turn is released from L-arginine by nitric oxide synthases. One of the main diseases of the cardiovascular system, endothelial dysfunction, leads to a diminished NO synthesis and thus increases vessel tone as well as the risk of thrombosis. The predominant therapeutic approach to this condition is a NO replacement therapy, as exemplified by organic nitrates, molsidomin, and other NO releasing substances. Recent advances in drug discovery provided a variety of other approaches to activate sGC, which may help to circumvent both the tolerance problem and some non-specific actions associated with NO donor drugs. Substances like BAY 41-2272 stimulate sGC in a heme-dependent fashion and synergize with NO, allowing to enhance the effects both of endogenous NO and of exogenous NO donors. On the other hand, heme-independent activators like BAY 58-2667 allow to activate sGC even if it is rendered unresponsive to NO due to oxidative stress or heme loss. Furthermore, a few substances have been described as specific inhibitors of sGC that allow to alleviate the effects of excess NO production as seen in shock. This review discusses the cardiovascular effects of heme-dependent and heme-independent activators as well as of inhibitors of sGC.
Bishydrocotarnines - Stereochemical Aspects
Creators: name: Okamoto, Y.
name: Dirnberger, D.
name: Burgemeister, T.
name: Dannhardt, G.
name: Wiegrebe, Wolfgang
Publisher: name: Universität Regensburg
Year: 1986
Subjects: subject: 540 Chemie

description: The bishydrocotarnines 2a and 2b1)' **) were converted into the urethanes 9a and 9b and into the carbamates 10a and 10b, which in turn were split to yield the sec. amines 11a and 11b. Cyclisation with diethyl oxalate led to the diketopiperazines 12a and 12b. Contrary to 9b, compound 9a was resolved into enantiomers on a cellulose carbamate column. This indicates that 9a is the D, L- and 9b is the meso form. NMR spectra of 12a and 12b led to an analogous conclusion. Die Bishydrocotarnine 2a und 2b1) werden in die Urethane 9a und 9b bzw. in die Carbamate 10a und 10b umgewandelt. Spaltung von 10a bzw. 10b in die sek. Amine 11a und 11b und deren Cyclisierung führen zu den Diketopiperazinen 12a und 12b. 9a ließ sich im Gegensatz zu 9b an einer Cellulosecarbamat-Säule in Enantiomere spalten. Danach ist 9a die D, L-, 9b die meso-Form. NMR-Spektren von 12a und 12b führen zu derselben Schlußfolgerung.
II INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE "SUSTAINABLE FORESTRY"
Creators: name: Tashkent State Agrarian University
name: International Scientific Journal Science And Innovation"
Publisher: name: Zenodo
Year: 2022

description: In order to ensure the execution of the order of the Cabinet of Ministers of the Republic of Uzbekistan dated March 7, 2022 No. 101-F on the approval of the plan of scientific and scientific and technical events held at the international and republican levels in the Republic of Uzbekistan in 2022, the Tashkent State Agrarian University is all the same with the international scientific journal “Science and Innovation” invites you to take part in the II International Conference on Sustainable Forestry – 2022, which will be held on October 14-15, 2022.
An ultrafast reconfigurable nanophotonic switch using wavefront shaping of light in a nonlinear nanomaterial
Creators: name: Strudley, Tom
name: Bruck, Roman
name: Mills, Ben
name: Muskens, Otto L.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Optics (physics.optics)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We demonstrate a new concept for reconfigurable nanophotonic devices exploiting ultrafast nonlinear control of shaped wavefronts in a multimode nanomaterial consisting of semiconductor nanowires. Femtosecond pulsed laser excitation of the nanowire mat is shown to provide an efficient nonlinear mechanism to control both destructive and constructive interference in a shaped wavefront. Modulations of up to 63% are induced by optical pumping, due to a combination of multimode dephasing and induced transient absorption. We show that part of the nonlinear phase dynamics can be inverted to provide a dynamical revival of the wavefront into an optimized spot with up to 18% increase of the peak to background ratio caused by pulsed laser excitation. The concepts of multimode nonlinear switching demonstrated here are generally extendable to other photonic and plasmonic systems and enable new avenues for ultrafast and reconfigurable nanophotonic devices.
description: 18 pages, 6 figures
Dithranol-Anion: UV/Vis-Spektrum und chemische Reaktivität
Creators: name: Retzow, A.
name: Wiegrebe, Wolfgang
Publisher: name: Universität Regensburg
Year: 1985
Subjects: subject: Psoriasis, dithranol-anion, electron excitation spectra, Diels-Alder-reaction
subject: 540 Chemie

description: Dithranol and its monoacetate as well as aloin and 9-hydroxyanthracen show a bathochromically shifted band in their electronexcitation spectra, when they are taken in alkaline solutions. The spectrum of aloin-anion was correlated with the isomerisation of aloin B into aloin A. These results and the Diels-Alder-reactivity of dithranol-anion indicate that R a a b' s biochemically highly active species, derived from dithranol, is its anion.
First Constraints on the Ultra-High Energy Neutrino Flux from a Prototype Station of the Askaryan Radio Array
Creators: name: ARA Collaboration
name: Allison, P.
name: Auffenberg, J.
name: Bard, R.
name: Beatty, J. J.
name: Besson, D. Z.
name: Bora, C.
name: Chen, C. -C.
name: Chen, P.
name: Connolly, A.
name: Davies, J. P.
name: DuVernois, M. A.
name: Fox, B.
name: Gorham, P. W.
name: Hanson, K.
name: Hill, B.
name: Hoffman, K. D.
name: Hong, E.
name: Hu, L. -C.
name: Ishihara, A.
name: Karle, A.
name: Kelley, J.
name: Kravchenko, I.
name: Landsman, H.
name: Laundrie, A.
name: Li, C. -J.
name: Liu, T.
name: Lu, M. -Y.
name: Maunu, R.
name: Mase, K.
name: Meures, T.
name: Miki, C.
name: Nam, J.
name: Nichol, R. J.
name: Nir, G.
name: O'Murchadha, A.
name: Pfendner, C. G.
name: Ratzlaff, K.
name: Richman, M.
name: Rotter, B.
name: Sandstrom, P.
name: Seckel, D.
name: Shultz, A.
name: Stockham, J.
name: Stockham, M.
name: Sullivan, M.
name: Touart, J.
name: Tu, H. -Y.
name: Varner, G. S.
name: Yoshida, S.
name: Young, R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The Askaryan Radio Array (ARA) is an ultra-high energy ($>10^{17}$ eV) cosmic neutrino detector in phased construction near the South Pole. ARA searches for radio Cherenkov emission from particle cascades induced by neutrino interactions in the ice using radio frequency antennas ($\sim150-800$ MHz) deployed at a design depth of 200 m in the Antarctic ice. A prototype ARA Testbed station was deployed at $\sim30$ m depth in the 2010-2011 season and the first three full ARA stations were deployed in the 2011-2012 and 2012-2013 seasons. We present the first neutrino search with ARA using data taken in 2011 and 2012 with the ARA Testbed and the resulting constraints on the neutrino flux from $10^{17}-10^{21}$ eV.
description: 26 pages, 15 figures. Since first revision, added section on systematic uncertainties, updated limits and uncertainty band with improvements to simulation, added appendix describing ray tracing algorithm. Final revision includes a section on cosmic ray backgrounds. Published in Astropart. Phys. J
ASSESSMENT OF THE INFLUENCE OF DURATION OF COHABITATION, OBSTETRICS & GYNECOLOGIC, BEHAVIORAL AND NUTRITIONAL RISK FACTORS ON PREECLAMPSIA AMONG NULLIPAROUS WOMEN IN SELECTED HOSPITALS OF WEST AMHARA ZONES, ETHIOPIA
Creators: name: MARU MEKIE (BSc.)
Publisher: name: Zenodo
Year: 2018

description: Introduction: Preeclampsia is the major cause of maternal and perinatal morbidity and mortality in developing countries. Identifying risk factors of preeclampsia is crucial for early diagnosis and management. Though several studies have been conducted related to preeclampsia, the influence of duration of cohabitation, obstetrics and gynaecologic, behavioural and nutritional factors have not been well understood among nulliparous women.

Objectives: To assess the effect of duration of cohabitation, obstetrics and gynaecologic, behavioural and nutritional risk factors on preeclampsia among nulliparous women in selected public hospitals of West Amhara Zones, Ethiopia
Forschungsdatenmanagement in der DFG-Förderung
Creators: name: Zentarra, Annabell
Publisher: name: Zenodo
Year: 2022
Subjects: DFG
SaxFDM-Tagung
Vortrag

description: Datenerhebung und Datenverarbeitung nehmen in vielen DFG-geförderten Forschungsprojekten eine zunehmend größere Rolle ein. Gleichzeitig zeigt sich eine disziplinäre Heterogenität bezüg­lich Standards zum Forschungsdatenmanagement. Im Fokus des Vortrags stehen die aktuellen Entwicklungen und Neuerungen, die das Forschungsdatenmanagement in der DFG-Förderung betref­fen. Dabei wird insbesondere auf die Neugestaltung des Antrags­punktes „Umgang mit den Forschungsdaten“ in den Leitfäden für die Erstellung von DFG-Anträgen, fachspezifische und überfach­liche Informationen für Antragstellende und Gutachtende auf unserer Webseite, sowie die zunehmende Relevanz des adäquaten Forschungsdatenmanagements im Begutachtungsprozess einge­gangen. Im Anschluss an den Vortrag sind Fragen und Anregungen aus dem Publikum herzlich willkommen.
Heat devices in nonlinear irreversible thermodynamics
Creators: name: Izumida, Y.
name: Okuda, K.
name: Roco, J. M. M.
name: Hernández, A. Calvo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We present results obtained by using nonlinear irreversible models for heat devices. In particular, we focus on the global performance characteristics, the maximum efficiency and the efficiency at maximum power regimes for heat engines, and the maximum coefficient of performance (COP) and the COP at maximum cooling power regimes for refrigerators. We analyze the key role played by the interplay between irreversibilities coming from heat leaks and internal dissipations. We also discuss the relationship between these results and those obtained by different models.
description: 14 pages, 7 figures
Sequencing DNA with Linux Cores and Nanopores
Creators: name: Eccles, David
Publisher: name: Zenodo
Year: 2019
Subjects: nanopore
sequencing
education
outreach

description: Sequenced reads (including signal-containing FAST5 files) from sequencing runs carried out as part of preparation for my LCA 2019 talk: Sequencing DNA with Linux Cores and Nanopores.

This is a mixed yoghurt, tomato and strawberry sample. DNA was extracted using the Qiagen PowerWater kit, and concentrated using Ampure XP beads to 18ng/μl. 7.5μl of the concentrated DNA sample was then processed with the Oxford Nanopore Rapid Barcoding kit, and sequenced for 15 minutes on an Oxford Nanopore MinION.

This is a backup dataset for my demonstration at the conference, in the very likely event that sample preparation does not produce sufficient amounts of DNA on the day for a good 15-minute sequencing run. It will be updated after the conference with any additional sequencing runs that are carried out.

The accessory Perl, R, and Python programs that I am using in my presentation can be found in my 'bioinfscripts' GitLab repository:

	https://gitlab.com/gringer/bioinfscripts

I also use LAST for sequence similarity searching during demultiplexing:

	Web interface http://lastweb.cbrc.jp
	Command line version http://last.cbrc.jp

If you're interested in purchasing the "genes in a T-shirt" that I'll probably be wearing during my talk, here's the Zazzle link to my virtual shop:

https://www.zazzle.co.nz/gringene
Ausgestaltung der Ökoregelungen in Deutschland - Stellungnahmen für das BMEL : Band 5 - Vorschläge zur Ausgestaltung der "Grünen Architektur" in Deutschland auf Basis der Legislativvorschläge der Europäischen Kommission zur Gemeinsamen Agrarpolitik nach 2020
Creators: name: Röder, Norbert
name: Bergschmidt, Angela
name: Birkenstock, Maren
name: Heidecke, Claudia
name: Kreins, Peter
name: Ledermüller, Sandra
name: Nieberg, Hiltrud
name: Osterburg, Bernhard
name: Sanders, Jürn
name: Schmidt, Thomas G.
name: Strassemeyer, Jörn
name: Weingarten, Peter
name: Witte, Thomas De
name: Zinnbauer, Maximilian
Publisher: name: Unknown
Year: 2023
Subjects: subject: Agricultural and Food Policy
subject: Land Economics/Use
subject: Resource /Energy Economics and Policy
subject: CAP post 2020
subject: Green Architecture
subject: payments for the environment

description: With the current reform of the Common agricultural policy (CAP), the EU aims to increase in particular the contribution of the agricultural sector to the protection of the climate, the environment and biodiversity in addition to income support. Therefore, the income support of the first pillar will be linked to compliance with 'extended conditionalities' and supplementary Eco-schemes will be introduced in the CAP’s first pillar from 01.01.2023 on. Farmers will receive additional payments if they participate voluntarily in the Eco-schemes. Furthermore, the EU wants to increase the flexibility of the agricultural policy and tailor it better to the needs of the different member states. For this purpose, the member states have to develop national CAP strategic plans and specify, among other, the Eco-schemes. On 01.06.2018, the European Commission published three draft regulations for the CAP. The CAP Strategic Plan Regulation (COM 2018/392 final) is the most important for the Green Architecture. Unless otherwise stated, all draft regulation references in the following refer to the proposal of this regulation from 01.06.2018 and not to the final adopted legal text. This paper reflects the state of discussions, as well as the legal and economic framework conditions in autumn 2018. Volume 5 of the Thünen Working Paper 180 presents the elements of the Green Architecture based on the Commission’s proposal. It also provides an overview of the relevant policy objectives in the field of environmental, climate and animal protection and their respective degree of target achievement in Germany. Against this background options the authors discuss different options to design a goal-oriented Green Architecture for Germany. It also reflects the authors' assessment of the suitability of the different elements of the Green Architecture for the implementation of (funding) measures.
description: DOI:10.3220/WP1690883819000
Cold Black Holes in the Harlow-Hayden Approach to Firewalls
Creators: name: Ong, Yen Chin
name: McInnes, Brett
name: Chen, Pisin
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Firewalls are controversial principally because they seem to imply departures from general relativistic expectations in regions of spacetime where the curvature need not be particularly large. One of the virtues of the Harlow-Hayden approach to the firewall paradox, concerning the time available for decoding of Hawking radiation emanating from charged AdS black holes, is precisely that it operates in the context of cold black holes, which are not strongly curved outside the event horizon. Here we clarify this point. The approach is based on ideas borrowed from applications of the AdS/CFT correspondence to the quark-gluon plasma. Firewalls aside, our work presents a detailed analysis of the thermodynamics and evolution of evaporating charged AdS black holes with flat event horizons. We show that, in one way or another, these black holes are always eventually destroyed in a time which, while long by normal standards, is short relative to the decoding time of Hawking radiation.
description: 32 pages, 10 figures, fixed some typos and slow loading of Fig.3; version accepted by Nucl. Phys. B
Semantic control of open hypertext Systems by typed objects
Creators: name: Hammwöhner, Rainer
name: Kuhlen, Rainer
Publisher: name: Universität Regensburg
Year: 1994
Subjects: subject: 020 Bibliotheks- und Informationswissenschaft

description: The C(K)onstance Hypertext System (KHS) is an elaborated example of an open hypertext System. Open hypertext Systems combine heterogeneous resources and different hypertext applications such as e-mail, text and image hypertexts with access to online databases or other information resources. These hypertexts, to which heterogeneous users have access, grow steadily in size. This paper takes an object-oriented approach and proposes a rigorous typing of hypertext objects to overcome the problems of open hypertext. The advantage of this typing is shown on an e-mail hypertext as a special application of the KHS system. KHS is written in Smalltalk and is being developed on UNIX-machines.
Supervised detection of anomalous light-curves in massive astronomical catalogs
Creators: name: Nun, Isadora
name: Pichara, Karim
name: Protopapas, Pavlos
name: Kim, Dae-Won
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: The development of synoptic sky surveys has led to a massive amount of data for which resources needed for analysis are beyond human capabilities. To process this information and to extract all possible knowledge, machine learning techniques become necessary. Here we present a new method to automatically discover unknown variable objects in large astronomical catalogs. With the aim of taking full advantage of all the information we have about known objects, our method is based on a supervised algorithm. In particular, we train a random forest classifier using known variability classes of objects and obtain votes for each of the objects in the training set. We then model this voting distribution with a Bayesian network and obtain the joint voting distribution among the training objects. Consequently, an unknown object is considered as an outlier insofar it has a low joint probability. Our method is suitable for exploring massive datasets given that the training process is performed offline. We tested our algorithm on 20 millions light-curves from the MACHO catalog and generated a list of anomalous candidates. We divided the candidates into two main classes of outliers: artifacts and intrinsic outliers. Artifacts were principally due to air mass variation, seasonal variation, bad calibration or instrumental errors and were consequently removed from our outlier list and added to the training set. After retraining, we selected about 4000 objects, which we passed to a post analysis stage by perfoming a cross-match with all publicly available catalogs. Within these candidates we identified certain known but rare objects such as eclipsing Cepheids, blue variables, cataclysmic variables and X-ray sources. For some outliers there were no additional information. Among them we identified three unknown variability types and few individual outliers that will be followed up for a deeper analysis.
description: 16 pages, 18 figures, published in The Astrophysical Journal
การยอมรับเทคโนโลยีเกษตรแม่นยำของเกษตรกรในอำเภอพระพุทธบาท จังหวัดสระบุรี
Creators: name: พรรษสรณ์ ชาญบัณฑิตนันท์
Publisher: name: คณะเทคโนโลยีการเกษตร มหาวิทยาลัยราชภัฏมหาสารคาม
Year: 2022
Subjects: การยอมรับ
เทคโนโลยี
เกษตรแม่นยำ
พระพุทธบาท
สระบุรี

description: วารสารเกษตรพระวรุณ, 19, 2, 82-90
Building application dependent hypertexts
Creators: name: Hammwöhner, Rainer
name: Rittberger, Marc
Publisher: name: Universität Regensburg
Year: 1997
Subjects: subject: 020 Bibliotheks- und Informationswissenschaft

description: The Konstanz Hypertext System offers a domain-specific developmental environment for the construction of large hypertexts. Through its flexibility, the structuring means employed in the Konstanz Hypertext System offers an instrument which permits one to respond directly to the demands relevant to specific applications in the construction of hypertexts. Especially the integration of information obtained from external resources is emphasized. After a discussion of the information sources which can be connected to the KHS a short introduction to the hypertext model of the KHS is provided. The role of structuring means in the integration of external information is pointed out. The scope of possible applications and the flexibility of the system are demonstrated by the following three comprehensive examples: resource discovery of online databases, management of e-mail and the compilation of an issue of an electronic journal.
Zum Mechanismus der Bischler-Napieralski-Reaktion, 2. Mitt.: o-Chlorierte β-Phenethylcarbonsäureamide als Nebenprodukte beim Ringschluss mit PCl5
Creators: name: Berger, U.
name: Dannhardt, G.
name: Wiegrebe, Wolfgang
Publisher: name: Universität Regensburg
Year: 1984
Subjects: subject: 540 Chemie

description: PC15 als Kondensationsmittel der Bischler-Napieralski-Reaktion gibt neben 3,4-Dihydroisochinolinen o-chlorierte ß-Phenethylcarbonsäureamide. Mögliche Mechanismen der Kernchlorierung werden in Modellversuchen geprüft. In addition to 3,4-dihydroisoquinolines o-chloro-ß-phenethylamides are formed in the Bischler-Napieralski reaction using PC15. Possible mechanisms for the chlorination were tested in model experiments.
title: New Zealand Report. Sustainable Governance Indicators 2022
Creators: name: Hellmann, Oliver
name: Curtin, Jennifer
name: Kalinowski, Thomas
Publisher: name: Bertelsmann Stiftung
Year: 2022
Subjects: Governance
Democracy
Regierungshandeln
Demokratie

description: New Zealand has weathered the global COVID-19 pandemic relatively well, both in terms of public health and economic performance. As of December 2021, the country had only recorded nine deaths per million population – the lowest such figure in the OECD. New Zealand’s economy also bounced back faster than expected and is projected to exit recession in 2022. The unemployment rate saw a sharp drop in 2021, from a peak of 5.3% in the September 2020 quarter to 3.4% in the September 2021 quarter.