cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Interplay between mitophagy and apoptosis defines a cell fate upon co-treatment of breast cancer cells with a recombinant fragment of human κ-casein and tumor necrosis factor-related apoptosis-inducing ligand
Creators: name: Wohlfromm, Fabian
name: Richter, Max
name: Otrin, Lado
name: Seyrek, Kamil
name: Vidaković-Koch, Tanja
name: Kuligina, Elena
name: Richter, Vladimir
name: Koval, Olga
name: Lavrik, Inna N.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2021
Subjects: subject: Apoptosis
subject: Mitophagy
subject: Milk proteins and peptides
subject: Lactaptin,
subject: TOM70
subject: 610.72

description: A recombinant fragment of human k-Casein, termed RL2, induces cell death of breast cancer cells; however,molecularmechanisms of RL2-mediated cell death have remained largely unknown. In the current study, we have decoded the molecular mechanism of the RL2-mediated cell death and found that RL2 acts via the induction of mitophagy. This was monitored by the loss of adenosine triphosphate production, LC3B-II generation, and upregulation of BNIP3 and BNIP3L/NIX, as well as phosphatase and tensin homolog-induced kinase 1. Moreover, we have analyzed the cross talk of this pathway with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis upon combinatorial treatment with RL2 and TRAIL. Strikingly, we found two opposite effects of this co-treatment. RL2 had inhibitory effects on TRAIL-induced cell death upon short-term co-stimulation. In particular, RL2 treatment blocked TRAIL-mediated caspase activation, cell viability loss, and apoptosis, which was mediated via the downregulation of the core proapoptotic regulators. Contrary to short-termco-treatment, upon long-term co-stimulation, RL2 sensitized the cells toward TRAIL-induced cell death; the latter observation provides the basis for the development of therapeutic approaches in breast cancer cells. Collectively, our findings have important implications for cancer therapy and reveal the molecular switches of the cross talk between RL2-induced mitophagy and TRAIL-mediated apoptosis.
Galactic Dynamos
Creators: name: Brandenburg, Axel
name: Ntormousi, Evangelia
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Spiral galaxies, including the Milky Way, have large-scale magnetic fields with significant energy densities. The dominant theory attributes these magnetic fields to a large-scale dynamo. We review the current status of dynamo theory and discuss various numerical simulations designed to explain either particular aspects of the problem or to reproduce galactic magnetic fields globally. Our main conclusions can be summarized as follows. Idealized direct numerical simulations produce mean magnetic fields, whose saturation energy density tends to decline with increasing magnetic Reynolds number. This is still an unsolved problem. Large-scale galactic magnetic fields of microgauss strengths can probably only be explained if helical magnetic fields of small or moderate length scales can rapidly be ejected or destroyed. Small-scale dynamos are important throughout a galaxy's life, and probably provide strong seed fields at early stages. The circumgalactic medium (CGM) may play an important role in driving dynamo action at small and large length scales. These interactions between the galactic disk and the CGM may provide important insights into our understanding of galactic dynamos. We expect future research in galactic dynamos to focus on the cosmological history of galaxies and the interaction with the CGM as means of replacing the idealized boundary conditions used in earlier work.
description: 47 pages, 15 figures, 4 tables
Additional file 1. of The Amsterdam wrist rules: the multicenter prospective derivation and external validation of a clinical decision rule for the use of radiography in acute wrist trauma
Creators: name: Walenkamp, Monique
name: Abdelali Bentohami
name: Slaar, Annelie
name: M. Beerekamp
name: Maas, Mario
name: L. Jager
name: Sosef, Nico
name: Velde, Romuald Van
name: Ultee, Jan
name: Steyerberg, Ewout
name: J. Goslings
name: Schep, Niels
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology

description: Number of patients with missings according to variable and characteristics of patients with and without prehensile grip strength as missing variable. (DOC 48 kb)
Dynamics of Induced Systems
Creators: name: Akin, Ethan
name: Auslander, Joseph
name: Nagar, Anima
Publisher: name: arXiv
Year: 2014
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: In this paper, we study the dynamical properties of actions on the space of compact subsets of the phase space. More precisely, if $X$ is a metric space, let $2^X$ denote the space of non-empty compact subsets of $X$ provided with the Hausdorff topology. If $f$ is a continuous self-map on $X$, there is a naturally induced continuous self-map $f_*$ on $2^X$. Our main theme is the interrelation between the dynamics of $f$ and $f_*$. For such a study, it is useful to consider the space $\mathcal{C}(K,X)$ of continuous maps from a Cantor set $K$ to $X$ provided with the topology of uniform convergence, and $f_*$ induced on $\mathcal{C}(K,X)$ by composition of maps. We mainly study the properties of transitive points of the induced system $(2^X,f_*)$ both topologically and dynamically, and give some examples. We also look into some more properties of the system $(2^X,f_*)$.
MAHMUD KOSHG'ARIY MA'NAVIY MEROSIDA TURKIY XALQLAR VA ULARNING TILLARI HAQIDA
Creators: name: Bektemirov, Shokir
Publisher: name: Zenodo
Year: 2024

description: O‘zbek davlatchiligini tiklanishi, miliy qadriyatlarning tiklanishi, o‘zbek tiliga “davlat tili” maqomining berilishi milliy identlikning tarixiy, ijtimoiy-siyosiy, ma’naviy-ma’rifiy jihatdan yangi sifat bosqichiga ko‘tardi. Prezident SH.M.Mirziyoev “Har birimiz davlat tiliga bo‘lgan e’tiborni mustaqillikka bo‘lgan e’tibor deb,  davlat tiliga ehtirom va sadoqatni, ona vatanga ehtirom va sadoqat deb bilishimiz, shunday qarashni hayotimiz qoidasiga aylantirishimiz kerak. Bu olijanob harakatni barchamiz o‘zimizdan, o‘z oilamiz va jamoamizdan boshlashimiz, ona tilimizga, urf-odat va qadriyatlarimizga hurmat, Vatanga mehrimizni amaliy faoliyatda namoyon etishimiz kerak[1].
Ground- and Excited-State Dipole Moments and Oscillator Strengths of Full Configuration Interaction Quality
Creators: name: Damour, Yann
name: Quintero-Monsebaiz, Raúl
name: Caffarel, Michel
name: Jacquemin, Denis
name: Kossoski, Fábris
name: Scemama, Anthony
name: Loos, Pierre-François
Publisher: name: arXiv
Year: 2022
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: We report ground- and excited-state dipole moments and oscillator strengths (computed in different ``gauges'' or representations) of full configuration interaction (FCI) quality using the selected configuration interaction method known as \textit{Configuration Interaction using a Perturbative Selection made Iteratively} (CIPSI). Thanks to a set encompassing 35 ground- and excited-state properties computed in 11 small molecules, the present near-FCI estimates allow us to assess the accuracy of high-order coupled-cluster (CC) calculations including up to quadruple excitations. In particular, we show that incrementing the excitation degree of the CC expansion (from CCSD to CCSDT or from CCSDT to CCSDTQ) reduces the average error with respect to the near-FCI reference values by approximately one order of magnitude.
description: 12 pages, 8 figures (supporting information available)
Additional file 1: Table S1. of A systematic review of comparative studies of tiotropium Respimat® and tiotropium HandiHaler® in patients with chronic obstructive pulmonary disease: does inhaler choice matter?
Creators: name: Dahl, Ronald
name: Kaplan, Alan
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Including study details for all publications included in this review. (DOCX 48 kb)
Exact asymptotics of the current in boundary dissipated quantum chains in large external fields
Creators: name: Lenarčič, Zala
name: Prosen, Tomaž
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Boundary driven quantum master equation for a general inhomogeneous (non-integrable) anisotropic Heisenberg spin $1/2$ chain, or an equivalent nearest neighbor interacting spinless fermion chain, is considered in the presence of a strong external field $f$. We present an exact closed form expression for large $f$ asymptotics of the current in the presence of pure incoherent source and sink dissipation at the boundaries. In application we demonstrate arbitrary large current rectification in the presence of interaction.
description: 5 pages, 2 figures
Additional file 13: Figure S5. of The Rat microRNA body atlas; Evaluation of the microRNA content of rat organs through deep sequencing and characterization of pancreas enriched miRNAs as biomarkers of pancreatic toxicity in the rat and dog
Creators: name: Smith, Aaron
name: Calley, John
name: Mathur, Sachin
name: Qian, Hui-Rong
name: Wu, Han
name: Farmen, Mark
name: Caiment, Florian
name: Bushel, Pierre
name: Jianying Li
name: Fisher, Craig
name: Kirby, Patrick
name: Koenig, Erik
name: Hall, David
name: Watson, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: miR-3473f-pre isomiRs in the testis. The isomiRs of select testis enriched miRNAs and their sequences are displayed in a heat map with tissues listed on the X-axis and isomiRs listed on the Y-axis. Expression levels are indicated by a range of colors with blue indicating low expression and red indicating high expression. IsomiRs of miR-3473f-pre display more expanded or restricted expression with respect to tissues. (PDF 14Â kb)
Additional file 7: Figure S5. of Genotyping-by-sequencing provides the discriminating power to investigate the subspecies of Daucus carota (Apiaceae)
Creators: name: Arbizu, Carlos
name: Ellison, Shelby
name: Senalik, Douglas
name: Simon, Philipp
name: Spooner, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Relationships among 144 accessions of the Daucus carota complex and outgroups from an exhaustive quartet sampling inference using 18,565 SNPs (10Â % missing imputed genotypes) obtained by GBS. Numbers above the branches represent bootstrap values, with only values higher than 70Â % shown. Names given to clades refer to the geographic origin and improvement status of the accessions of the D. carota complex. ME & E refers to Middle East & Europe. Accessions designated by double stars are misplaced relative to the maximum likelihood topology of the Daucus carota complex using the same number of SNPs. The outgroup taxon is D. syrticus. (PDF 1 MB)
Orexin deficiency modulates cognitive flexibility in a sex-dependent manner
Creators: name: Durairaja, Archana
name: Fendt, Markus
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2021
Subjects: subject: Animal models of schizophrenia
subject: Attentional set shifting
subject: Anxiety
subject: Cognitive flexibility
subject: Food consumption,
subject: Learning and memory
subject: Narcolepsy
subject: Neuropeptides
subject: Orexin
subject: Transgenic mice
subject: 610.72

description: Cognitive flexibility is an important executive function and refers to the ability to adapt behaviors in response to changes in the environment. Of note, many brain disorders are associated with impairments in cognitive flexibility. Several classical neurotransmitter systems including dopamine, acetylcholine and noradrenaline are shown to be important for cognitive flexibility, however, there is not much known about the role of neuropeptides. The neuropeptide orexin, which is brain-widely released by neurons in the lateral hypothalamus, is a major player in maintaining sleep/wake cycle, feeding behavior, arousal, and motivational behavior. Recent studies showed a role of orexin in attention, cognition and stress-induced attenuation of cognitive flexibility by disrupting orexin signaling locally or systemically. However, it is not known so far whether brainwide reduction or loss of orexin affects cognitive flexibility. We investigated this question by testing male and female orexin-deficient mice in the attentional set shifting task (ASST), an established paradigm of cognitive flexibility. We found that orexin deficiency impaired the intra-dimensional shift phase of the ASST selectively in female homozygous orexin-deficient mice and improved the first reversal learning phase selectively in male homozygous orexin-deficient mice. We also found that these orexin-mediated sex-based modulations of cognitive flexibility were not correlated with trait anxiety, narcoleptic episodes, and reward consumption. Our findings highlight a sexually dimorphic role of orexin in regulating cognitive flexibility and the need for further investigations of sex-specific functions of the orexin circuitry.
Quantification and Aggregation over Concepts of the Ontology
Creators: name: Carbonnelle, Pierre
name: Van der Hallen, Matthias
name: Denecker, Marc
Publisher: name: arXiv
Year: 2022
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: We argue that in some KR applications, we want to quantify over sets of concepts formally represented by symbols in the vocabulary. We show that this quantification should be distinguished from second-order quantification and meta-programming quantification. We also investigate the relationship with concepts in intensional logic. We present an extension of first-order logic to support such abstractions, and show that it allows writing expressions of knowledge that are elaboration tolerant. To avoid nonsensical sentences in this formalism, we refine the concept of well-formed sentences, and propose a method to verify well-formedness with a complexity that is linear with the number of tokens in the formula. We have extended FO(.), a Knowledge Representation language, and IDP-Z3, a reasoning engine for FO(.), accordingly. We show that this extension was essential in accurately modelling various problem domains in an elaboration-tolerant way, i.e., without reification.
description: In Proceedings ICLP 2023, arXiv:2308.14898
Singular deformations of nearly $R^2$ inflation potentials
Creators: name: Odintsov, S. D.
name: Oikonomou, V. K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate in which cases a singular evolution with a singularity of Type IV, can be consistently incorporated in deformations of the $R^2$ inflationary potential. After demonstrating the difficulties that the single scalar field description is confronted with, we use a general two scalar fields model without other matter fluids, to describe the Type IV singular evolution, with one of the two scalar fields being canonical. By appropriately choosing the non-canonical scalar field, we show that the canonical scalar field corresponds to a potential that is nearly the $R^2$ inflation potential. If the Type IV singularity occurs at the end of inflation, the Universe's dynamical evolution near inflation is determined effectively by the canonical scalar field and at late-time the evolution is effectively determined by the non-canonical scalar. We also discuss the evolution of the Universe in terms of the effective equation of state and we show that the Type IV singularity, that occurs at the end of inflation, drives late-time acceleration. If however the singularity occurs at late-time, this might affect the inflationary era. We also investigate which Jordan frame pure $F(R)$ gravity corresponds to the nearly $R^2$ inflation scalar potentials we found. The stability of the solutions in the two scalar fields case is also studied and also we investigate how Type IV singularities can be incorporated in certain limiting cases of $R+R^p$ gravity in the Einstein frame. Finally, we briefly discuss a physical appealing scenario triggered by instabilities in the dynamical system that describes the evolution of the scalar fields.
description: Revised Version, to appear in CQG
Ill-posedness of a quasilinear wave equation in two dimensions for data in $H^{7/4}$
Creators: name: Ohlmann, Gaspard
Publisher: name: arXiv
Year: 2021
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In this article, we study the ill-posedness of a quasilinear wave equation. It was shown by Tataru and Smith in 2005 that for any $s>7/4$ (or $11/4$ in our situation), the equation is well-posed in $H^{s}\times H^{s-1}$. We show a sharpness result by exhibiting a quasilinear wave equation and an initial data such that the Cauchy problem is ill-posed for in $H^{11/4} (\ln H)^{-β}\times H^{7/4} (\ln H^{-β})$.
MOESM2 of To what extent do mesophotic coral ecosystems and shallow reefs share species of conservation interest?
Creators: name: Laverick, Jack
name: Andradi-Brown, Dominic
name: Exton, Dan
name: Bongaerts, Pim
name: Bridge, Tom
name: Lesser, Michael
name: Pyle, Richard
name: Slattery, Marc
name: Wagner, Daniel
name: Rogers, Alex
Publisher: name: Figshare
Year: 2016
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Additional file 2. Test libraryâ  a list of all papers used to determine the effectiveness of trialled search strings.
Stress-energy tensor of the quantized massive fields in Schwarzschild-Tangherlini spacetimes. The back reaction
Creators: name: Matyjasek, Jerzy
name: Sadurski, Pawel
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We construct and study the approximate stress-energy tensor of the quantized massive scalar field in higher dimensional Schwarzschild-Tangherlini spacetimes. The stress-energy tensor is calculated within the framework of the Schwinger-DeWitt approach. It is shown that in $N$-dimensional spacetime the main approximation can be obtained from the effective action constructed form the coincidence limit of the Hadamard-DeWitt coefficient $a_{k},$ where $k-1$ is the integer part of $N/2$. The back reaction of the quantized field upon the black hole spacetime is analyzed and the quantum-corrected Komar mass and the Hawking temperature is calculated. It is shown that for the minimal and conformal coupling the increase of the Komar mass of the quantum corrected black hole leads to the decrease of its Hawking temperature. This is not generally true for more exotic values of the coupling parameter. The general formula describing the vacuum polarization, $ \langle ϕ^{2} \rangle,$ is constructed and briefly examined.
On the associativity of 1-loop corrections to the celestial operator product in gravity
Creators: name: Bittleston, Roland
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The question of whether the holomorphic collinear singularities of graviton amplitudes define a consistent chiral algebra has garnered much recent attention. We analyse a version of this question for infinitesimal perturbations around the self-dual sector of 4d Einstein gravity. The singularities of tree amplitudes in such perturbations do form a consistent chiral algebra, however at 1-loop its operator products are corrected by the effective graviton vertex. We argue that this chiral algebra can be interpreted as the universal holomorphic surface defect in the twistor uplift of self-dual gravity, and show that the same correction is induced by an anomalous diagram in the bulk-defect system. The 1-loop holomorphic collinear singularities do not form a consistent chiral algebra. The failure of associativity can be traced to the existence of a recently discovered gravitational anomaly on twistor space. It can be restored by coupling to an unusual 4th-order gravitational axion, which cancels the anomaly by a Green-Schwarz mechanism. Alternatively, the anomaly vanishes in certain theories of self-dual gravity coupled to matter, including in self-dual supergravity.
description: 61 pages, 11 figures; v2: clarifications added, typos corrected; v3: published in JHEP
title: On the real world practice of Behaviour Driven Development
Creators: name: Islam, Gibrail
Publisher: name: University of Glasgow
Year: 2024

description: Surveys of industry practice over the last decade suggest that Behaviour Driven Development is a popular Agile practice. For example, 19% of respondents to the 14th State of Agile annual survey reported using BDD, placing it in the top 13 practices reported. As well as potential benefits, the adoption of BDD necessarily involves an additional cost of writing and maintaining Gherkin features and scenarios, and (if used for acceptance testing,) the associated step functions. Yet there is a lack of published literature exploring how BDD is used in practice and the challenges experienced by real world software development efforts. This gap is significant because without understanding current real world practice, it is hard to identify opportunities to address and mitigate challenges. In order to address this research gap concerning the challenges of using BDD, this thesis reports on a research project which explored: (a) the challenges of applying agile and undertaking requirements engineering in a real world context; (b) the challenges of applying BDD specifically and (c) the application of BDD in open-source projects to understand challenges in this different context.

For this purpose, we progressively conducted two case studies, two series of interviews, four iterations of action research, and an empirical study. The first case study was conducted in an avionics company to discover the challenges of using an agile process in a large scale safety critical project environment. Since requirements management was found to be one of the biggest challenges during the case study, we decided to investigate BDD because of its reputation for requirements management. The second case study was conducted in the company with an aim to discover the challenges of using BDD in real life. The case study was complemented with an empirical study of the practice of BDD in open source projects, taking a study sample from the GitHub open source collaboration site.

As a result of this Ph.D research, we were able to discover: (i) challenges of using an agile process in a large scale safety-critical organisation, (ii) current state of BDD in practice, (iii) technical limitations of Gherkin (i.e., the language for writing requirements in BDD), (iv) challenges of using BDD in a real project, (v) bad smells in the Gherkin specifications of open source projects on GitHub. We also presented a brief comparison between the theoretical description of BDD and BDD in practice. This research, therefore, presents the results of lessons learned from BDD in practice, and serves as a guide for software practitioners planning on using BDD in their projects.
Additional file 1: Table S1. of Genotyping-by-sequencing provides the discriminating power to investigate the subspecies of Daucus carota (Apiaceae)
Creators: name: Arbizu, Carlos
name: Ellison, Shelby
name: Senalik, Douglas
name: Simon, Philipp
name: Spooner, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: The 162 accessions of Daucus, and two accessions of related genera characterized in this study, improvement status, locality information and new identification. (PDF 23.5 kb)
Direct observation of geometric phase in dynamics around a conical intersection
Creators: name: Valahu, Christophe H.
name: Olaya-Agudelo, Vanessa C.
name: MacDonell, Ryan J.
name: Navickas, Tomas
name: Rao, Arjun D.
name: Millican, Maverick J.
name: Pérez-Sánchez, Juan B.
name: Yuen-Zhou, Joel
name: Biercuk, Michael J.
name: Hempel, Cornelius
name: Tan, Ting Rei
name: Kassal, Ivan
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Conical intersections are ubiquitous in chemistry and physics, often governing processes such as light harvesting, vision, photocatalysis, and chemical reactivity. They act as funnels between electronic states of molecules, allowing rapid and efficient relaxation during chemical dynamics. In addition, when a reaction path encircles a conical intersection, the molecular wavefunction experiences a geometric phase, which can affect the outcome of the reaction through quantum-mechanical interference. Past experiments have measured indirect signatures of geometric phases in scattering patterns and spectroscopic observables, but there has been no direct observation of the underlying wavepacket interference. Here, we experimentally observe geometric-phase interference in the dynamics of a wavepacket travelling around an engineered conical intersection in a programmable trapped-ion quantum simulator. To achieve this, we develop a technique to reconstruct the two-dimensional wavepacket densities of a trapped ion. Experiments agree with the theoretical model, demonstrating the ability of analog quantum simulators -- such as those realised using trapped ions -- to accurately describe nuclear quantum effects.
description: 10 pages, 5 figures
Additional file 8: Figure S6. of Genotyping-by-sequencing provides the discriminating power to investigate the subspecies of Daucus carota (Apiaceae)
Creators: name: Arbizu, Carlos
name: Ellison, Shelby
name: Senalik, Douglas
name: Simon, Philipp
name: Spooner, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Relationships among 144 accessions of the Daucus carota complex and outgroups from an exhaustive quartet sampling inference using 43,713 SNPs (30Â % missing imputed genotypes) obtained by GBS. Numbers above branches represent bootstrap values, with only values higher than 70Â % shown. Names given to clades refer to the geographic origin and improvement status of the accessions of the D. carota complex. ME & E refers to Middle East & Europe. Accessions designated by double stars are misplaced relative to the maximum likelihood topology of the Daucus carota complex using the same number of SNPs. The outgroup taxon is D. syrticus. (PDF 1 MB)
IMPORTÂNCIA DA EQUIPE INTERPROFISSIONAL NO DIAGNÓSTICO, TRATAMENTO E REABILITAÇÃO DE ANQUILOGLOSSIA EM CRIANÇAS DE 0 A 6 MESES
Creators: name: Ariane Alves Pollis
name: Karine Gonçalves Martinenghi
name: Beatriz Essenfelder Borges
Publisher: name: Zenodo
Year: 2023
Subjects: Anquiloglossia, amamentação, frênulo lingual, equipe interprofissional, lactente, freios orais.

description: A amamentação é a fase mais importante da vida do ser humano, fornecendo suas primeiras imunizações, nutrientes e vitaminas, responsáveis por seu crescimento e desenvolvimento. E neste início da vida, podem surgir um dos primeiros ofensores ao aleitamento materno, a anquiloglossia, popularmente chamada de "língua presa", que possui causa desconhecida, mas que muitas vezes, pode estar relacionada a herança genética e/ou hereditária, prevalecendo em bebês do sexo masculino, e podendo trazer impactos imediatos no aleitamento materno, para o neonato e para as mães. Com isso, o objetivo deste estudo é apresentar a importância do envolvimento da equipe interdisciplinar no diagnóstico, tratamento e reabilitação de anquiloglossia em crianças de 0 a 6 meses de vida. Para isso, foi realizada uma revisão integrativa, dividida em 6 etapas, onde, após uma criteriosa avaliação, foram selecionados 18 artigos que melhor retrataram o tema. Diante disso, identificou-se que há diversos protocolos de diagnóstico para a anquiloglossia, no entanto, não há um "padrão ouro" de avaliação para atuação dos profissionais envolvidos, dificultando na universalização de uma solução para esta doença. Ressalta-se que independente da opção de tratamento, conservadora ou intervencionista, é essencial ter a participação de profissionais especialistas no fortalecimento e mobilidade da língua, no manejo da amamentação, e em alguns casos em correções posturais, a fim de que se tenha um processo de reabilitação segura e eficaz da correção do frênulo alterado. Desta forma, é possível concluir que a atuação na anquiloglossia não depende de apenas uma especialidade médica, sendo necessário a atuação de diferentes profissionais aptos e atualizados em alterações de freios orais, assim como, que o diagnóstico e tratamento precoce são essenciais para garantir uma efetividade do aleitamento materno, a fim de que o binômio mãe e filho tenham uma maior qualidade de vida, evitando um desmame precoce, e colaborando para que a amamentação seja duradoura e sustentável,  permitindo  o desenvolvimento de toda sociedade.
Dilute magnetic semiconductor and half metal behaviors in 3d transition-metal doped black and blue phosphorenes: a first-principles study
Creators: name: Yu, Weiyang
name: Zhu, Zhili
name: Niu, Chun-Yao
name: Li, Chong
name: Cho, Jun-Hyung
name: Jia, Yu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: We present first-principles density-functional calculations for the structural, electronic, and magnetic properties of substitutional 3d transition metal (TM) impurities in two-dimensional black and blue phosphorenes. We find that the magnetic properties of such substitutional impurities can be understood in terms of a simple model based on the Hund's rule. The TM-doped black phosphorenes with Ti, V, Cr, Mn, Fe and Ni impurities show dilute magnetic semiconductor (DMS) properties while those with Sc and Co impurities show nonmagnetic properties. On the other hand, the TM-doped blue phosphorenes with V, Cr, Mn and Fe impurities show DMS properties, those with Ti and Ni impurities show half-metal properties, whereas Sc and Co doped systems show nonmagnetic properties. We identify two different regimes depending on the occupation of the hybridized electronic states of TM and phosphorous atoms: (i) bonding states are completely empty or filled for Sc- and Co-doped black and blue phosphorenes, leading to non-magnetic; (ii) non-bonding d states are partially occupied for Ti-, V-, Cr-, Mn-, Fe- and Ni-doped black and blue phosphorenes, giving rise to large and localized spin moments. These results provide a new route for the potential applications of dilute magnetic semiconductor and half-metal in spintronic devices by employing black and blue phosphorenes.
description: 9 pages, 7 figures
Additional file 12: Figure S10. of Genotyping-by-sequencing provides the discriminating power to investigate the subspecies of Daucus carota (Apiaceae)
Creators: name: Arbizu, Carlos
name: Ellison, Shelby
name: Senalik, Douglas
name: Simon, Philipp
name: Spooner, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Box plot analyses of the 23 morphological characters examined for members of Daucus carota complex (subsp. sativus not included) in this study. The box plot displays individual plant values for median, 25 and 75Â % percentile, range, and outliers. (PDF 17 MB)
Interpretable Modeling and Reduction of Unknown Errors in Mechanistic Operators
Creators: name: Toloubidokhti, Maryam
name: Kumar, Nilesh
name: Li, Zhiyuan
name: Gyawali, Prashnna K.
name: Zenger, Brian
name: Good, Wilson W.
name: MacLeod, Rob S.
name: Wang, Linwei
Publisher: name: arXiv
Year: 2022
Subjects: subject: Image and Video Processing (eess.IV)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Prior knowledge about the imaging physics provides a mechanistic forward operator that plays an important role in image reconstruction, although myriad sources of possible errors in the operator could negatively impact the reconstruction solutions. In this work, we propose to embed the traditional mechanistic forward operator inside a neural function, and focus on modeling and correcting its unknown errors in an interpretable manner. This is achieved by a conditional generative model that transforms a given mechanistic operator with unknown errors, arising from a latent space of self-organizing clusters of potential sources of error generation. Once learned, the generative model can be used in place of a fixed forward operator in any traditional optimization-based reconstruction process where, together with the inverse solution, the error in prior mechanistic forward operator can be minimized and the potential source of error uncovered. We apply the presented method to the reconstruction of heart electrical potential from body surface potential. In controlled simulation experiments and in-vivo real data experiments, we demonstrate that the presented method allowed reduction of errors in the physics-based forward operator and thereby delivered inverse reconstruction of heart-surface potential with increased accuracy.
description: 11 pages, Conference: Medical Image Computing and Computer Assisted Intervention
Additional file 6: Figure S4. of Genotyping-by-sequencing provides the discriminating power to investigate the subspecies of Daucus carota (Apiaceae)
Creators: name: Arbizu, Carlos
name: Ellison, Shelby
name: Senalik, Douglas
name: Simon, Philipp
name: Spooner, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Bayesian phylogenetic tree of 144 accessions of the Daucus carota complex and outgroups using 18,565 SNPs (10Â % missing imputed genotypes) obtained by GBS. Numbers above the branches represent posterior probabilities, with only values higher than 0.7 shown. Names given to clades refer to the geographic origin and improvement status of the accessions of the D. carota complex. The outgroup taxon is D. syrticus. (PDF 1 MB)
Micro-Architectural features as soft-error induced fault executions markers in embedded safety-critical systems: a preliminary study
Creators: name: Kasap, Deniz
name: Carpegna, Alessio
name: Savino, Alessandro
name: Di Carlo, Stefano
Publisher: name: arXiv
Year: 2022
Subjects: subject: Hardware Architecture (cs.AR)
subject: FOS: Computer and information sciences

description: Radiation-induced soft errors are one of the most challenging issues in Safety Critical Real-Time Embedded System (SACRES) reliability, usually handled using different flavors of Double Modular Redundancy (DMR) techniques. This solution is becoming unaffordable due to the complexity of modern micro-processors in all domains. This paper addresses the promising field of using Artificial Intelligence (AI) based hardware detectors for soft errors. To create such cores and make them general enough to work with different software applications, microarchitectural attributes are a fascinating option as candidate fault detection features. Several processors already track these features through dedicated Performance Monitoring Unit (PMU). However, there is an open question to understand to what extent they are enough to detect faulty executions. Exploiting the capability of gem5 to simulate real computing systems, perform fault injection experiments and profile microarchitectural attributes (i.e., gem5 Stats), this paper presents the results of a comprehensive analysis regarding the potential attributes to detect soft error and the associated models that can be trained with these features.
Observation of Dicke Superradiance for Two Artificial Atoms in a Cavity with High Decay Rate
Creators: name: Mlynek, J. A.
name: Abdumalikov, A. A.
name: Eichler, C.
name: Wallraff, A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: An individual excited two level system decays to its ground state by emitting a single photon in a process known as spontaneous emission. In accordance with quantum theory the probability of detecting the emitted photon decreases exponentially with the time passed since the excitation of the two level system. In 1954 Dicke first considered the more subtle situation in which two emitters decay in close proximity to each other. He argued that the emission dynamics of a single two level system is altered by the presence of a second one, even if it is in its ground state. Here, we present a close to ideal realization of Dicke's original two-spin Gedankenexperiment, using a system of two individually controllable superconducting qubits weakly coupled to a microwave cavity with a fast decay rate. The two-emitter case of superradiance is explicitly demonstrated both in time-resolved measurements of the emitted power and by fully reconstructing the density matrix of the emitted field in the photon number basis.
End-to-end deep multi-score model for No-reference stereoscopic image quality assessment
Creators: name: Messai, Oussama
name: Chetouani, Aladine
Publisher: name: arXiv
Year: 2022
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: Multimedia (cs.MM)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Deep learning-based quality metrics have recently given significant improvement in Image Quality Assessment (IQA). In the field of stereoscopic vision, information is evenly distributed with slight disparity to the left and right eyes. However, due to asymmetric distortion, the objective quality ratings for the left and right images would differ, necessitating the learning of unique quality indicators for each view. Unlike existing stereoscopic IQA measures which focus mainly on estimating a global human score, we suggest incorporating left, right, and stereoscopic objective scores to extract the corresponding properties of each view, and so forth estimating stereoscopic image quality without reference. Therefore, we use a deep multi-score Convolutional Neural Network (CNN). Our model has been trained to perform four tasks: First, predict the left view's quality. Second, predict the quality of the left view. Third and fourth, predict the quality of the stereo view and global quality, respectively, with the global score serving as the ultimate quality. Experiments are conducted on Waterloo IVC 3D Phase 1 and Phase 2 databases. The results obtained show the superiority of our method when comparing with those of the state-of-the-art. The implementation code can be found at: https://github.com/o-messai/multi-score-SIQA
Additional file 3: Figure S1. of Genotyping-by-sequencing provides the discriminating power to investigate the subspecies of Daucus carota (Apiaceae)
Creators: name: Arbizu, Carlos
name: Ellison, Shelby
name: Senalik, Douglas
name: Simon, Philipp
name: Spooner, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Phylogenomics of Daucus from a maximum likelihood analysis using 164 accessions and 10,814 SNPs (10Â % missing imputed genotypes) obtained by GBS. Numbers above branches represent bootstrap values, with only values higher than 70Â % shown. Names given to clades refer to the geographic origin and improvement status of the accessions of the D. carota complex. Clades A and B corresponds to the two main groups of the Daucus phylogeny. (PDF 1 MB)
A uniqueness theorem for 3D semilinear wave equations satisfying the null condition
Creators: name: Yu, Dongxiao
Publisher: name: arXiv
Year: 2021
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In this paper, we prove a uniqueness theorem for a system of semilinear wave equations satisfying the null condition in $\mathbb{R}^{1+3}$. Suppose that two global solutions with $C_c^\infty$ initial data have equal initial data outside a ball and equal radiation fields outside a light cone. We show that these two solutions are equal either outside a hyperboloid or everywhere in the spacetime, depending on the sizes of the ball and the light cone.
description: 43 pages, 1 figure. Revised based on a referee report
The physicochemical and phylogenetic properties of twelve spike glycoprotein models for SARS-CoV-2 from China, Iran, and Tunisia
Creators: name: Samih, Odhaib
name: Miaad, Jassim
name: Jamil, Dina
name: Al-Aubaidy, Hayder
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 320211
subject: Infectious diseases
classificationCode: 310706
subject: Virology

description: No description supplied
Additional file 2: Table S2. of Genotyping-by-sequencing provides the discriminating power to investigate the subspecies of Daucus carota (Apiaceae)
Creators: name: Arbizu, Carlos
name: Ellison, Shelby
name: Senalik, Douglas
name: Simon, Philipp
name: Spooner, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Summary of processing GBS data of Daucus. (PDF 11 kb)
Nonhomogeneous quadratic duality and curvature
Creators: name: Positselski, Leonid
Publisher: name: arXiv
Year: 2014
Subjects: subject: Rings and Algebras (math.RA)
subject: Category Theory (math.CT)
subject: FOS: Mathematics

description: This is a slightly corrected version of the article published by Functional Analysis and its Applications in 1993. We define the quadratic duality for algebras with nonhomogeneous relations; the duality between the algebra of differential operators and the multiplicative de Rham complex is a classical example. The scalar part of the relations is interpreted as the curvature. Chern classes of nonhomogeneneous quadratic algebras are introduced as certain obstructions; the Chern-Simons classes are also discussed. The Poincare-Birkhoff-Witt theorem is considered in the context of the duality, and its simple proof is given.
description: Plain TeX, 11 pages; v.2: several notes added at the end, (Journal ref Russian)
Dual functional liposomes carrying antioxidants against tau hyperphosphorylation and apoptosis of neurons
Creators: name: Yung-Chih Kuo
name: Yung-I Lou
name: Rajendiran Rajesh
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology

description: Quercetin (QU) and rosmarinic acid (RA) were loaded in phosphatidic acid-liposomes (QU/RA-PA-liposomes) with surface apolipoprotein E (ApoE) using a process of thin-film hydration, followed by covalent crosslinking to activate biological pathways for penetrating the blood–brain barrier (BBB) and redeeming the neuronal apoptosis from attack of β-amyloid 1-42 (Aβ1-42) and neurofibrillary tangles. The conjugation of liposomes with PA improved the activity of QU and RA against neurotoxicity of Aβ1-42. The fluorescent images of brain capillaries revealed that surface modification with ApoE improved the permeation ability of QU/RA-PA-ApoE-liposomes across the BBB. In addition, the highest therapeutic efficacy was obtained in the case of QU/RA-PA-ApoE-liposomes, compared to other QU/RA formulations studied using in vivo Aβ1-42-insulted rats mimicking Alzheimer’s disease (AD). The cellular and molecular evidence from AD rats included the decrease in Aβ1-42 plaque formation and interleukin-6 secretion, increase in the neuronal count in Nissl staining, and reduction in the expression of phosphorylated extracellular signal-regulated kinase 1/2, c-Jun N-terminal kinase, p38 kinase and tau protein at serine 202 as well as caspase-3. The use of PA-ApoE-liposomes as a dual targeting formulation enhances the QU and RA ability to infiltrate the BBB, docks Aβ1-42 plaques and can be a potent approach to rescue degenerated neurons from AD.
The physicochemical and phylogenetic properties of twelve spike glycoprotein models for SARS-CoV-2 from China, Iran, and Tunisia
Creators: name: Odhaib Samih
name: Miaad, Jassim
name: Jamil, Dina
name: Al-Aubaidy, Hayder
Publisher: name: La Trobe
Year: 2020
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences

description: No description supplied