cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Lessons learned while starting multi-institutional genetics research in diverse populations: A report from the Clinical Sequencing Evidence-Generating Research (CSER) consortium
Creators: name: Bensen, J.T.
name: Smith, H.S.
name: Sahin-Hodoglugil, N.
name: Murali, P.
name: Ferket, B.S.
name: Russell, H.
name: Finnila, C.
name: Hindorff, L.A.
Publisher: name: Elsevier Inc.
Year: 2023

description: Background: Increasing diversity in clinical trial participation is necessary to improve health outcomes and requires addressing existing social, structural, and geographic barriers. The Clinical Sequencing Evidence-Generating Research Consortium (CSER) included six research projects to enroll historically underrepresented/underserved (UR/US) populations in clinical genomics research. Delays and project re-designs emerged shortly after work began. Understanding common experiences of these projects may inform future trial implementation. Methods: Semi-structured interviews with six CSER principal investigators and seven project managers were performed. An interview guide included questions of research/clinical infrastructure, logistics across sites, language, communication, and allocation of grant-related resources. Interviews were recorded, transcribed verbatim; transcripts were analyzed using inductive coding, thematic analysis and consensus building. Results: All projects collaborating with new clinical sub-sites to recruit UR/US populations. Refining trial logistics continued long after enrollment for all projects. Themes of challenges included: sub-site customization for workflow and genetics support, conflicting input from participant advisory groups and approval bodies, developing research personnel, complex data management structures, and external changes (e.g. subcontractors ending contracts) that required redesign. Themes of beneficial lessons included: domains with prior experience were easier, develop project champions at each sub-site, structure communication within the research team, and simplify research design when possible. Conclusions: The operational aspects of expanding clinical research into novel sub-sites are significant and require investment of time and resources. The themes arising from these interviews suggest priority areas for more quantitative analyses in the future including multi-institutional approval policies and processes, data management structures, and incremental research complexity.
Additional file 2 of The score after 10 years of registration of systematic review protocols
Creators: name: van der Braak, Kim
name: Ghannad, Mona
name: Orelio, Claudia
name: Heus, Pauline
name: Damen, Johanna A. A.
name: Spijker, René
name: Robinson, Karen
name: Lund, Hans
name: Hooft, Lotty
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Supplementary Figure 1. Countries of origen of the corresponding author. Supplementary Table 2. Frequency of included publications per journal title. Supplementary Table 3. outcomes of logistic regression. Supplementary Table 4. Frequency of SR protocols published in journals/ databases other than protocol registries.
Direct Activation of Human Phospholipase C by Its Well Known Inhibitor U73122
Creators: name: Bourdon, David M.
name: Costales, Chester L.
name: White, Wendy L.
name: Sondek, John
name: Thakker, Dhiren R.
name: Hicks, Stephanie N.
name: Klein, Ryan R.
name: Williams, Jon D.
name: Wagner, Craig D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Phospholipase C (PLC) enzymes are an important family of regulatory proteins involved in numerous cellular functions, primarily through hydrolysis of the polar head group from inositol-containing membrane phospholipids. {"type":"entrez-nucleotide","attrs":{"text":"U73122","term_id":"4098075","term_text":"U73122"}}U73122 (1-(6-((17β-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione), one of only a few small molecules reported to inhibit the activity of these enzymes, has been broadly applied as a pharmacological tool to implicate PLCs in diverse experimental phenotypes. The purpose of this study was to develop a better understanding of molecular interactions between {"type":"entrez-nucleotide","attrs":{"text":"U73122","term_id":"4098075","term_text":"U73122"}}U73122 and PLCs. Hence, the effects of {"type":"entrez-nucleotide","attrs":{"text":"U73122","term_id":"4098075","term_text":"U73122"}}U73122 on human PLCβ3 (hPLCβ3) were evaluated in a cell-free micellar system. Surprisingly, {"type":"entrez-nucleotide","attrs":{"text":"U73122","term_id":"4098075","term_text":"U73122"}}U73122 increased the activity of hPLCβ3 in a concentration- and time-dependent manner; up to an 8-fold increase in enzyme activity was observed with an EC50 = 13.6 ± 5 μm. Activation of hPLCβ3 by {"type":"entrez-nucleotide","attrs":{"text":"U73122","term_id":"4098075","term_text":"U73122"}}U73122 required covalent modification of cysteines as evidenced by the observation that enzyme activation was attenuated by thiol-containing nucleophiles, l-cysteine and glutathione. Mass spectrometric analysis confirmed covalent reaction with {"type":"entrez-nucleotide","attrs":{"text":"U73122","term_id":"4098075","term_text":"U73122"}}U73122 at eight cysteines, although maximum activation was achieved without complete alkylation; the modified residues were identified by LC/MS/MS peptide sequencing. Interestingly, {"type":"entrez-nucleotide","attrs":{"text":"U73122","term_id":"4098075","term_text":"U73122"}}U73122 (10 μm) also activated hPLCγ1 (>10-fold) and hPLCβ2 (∼2-fold); PLCδ1 was neither activated nor inhibited. Therefore, in contrast to its reported inhibitory potential, {"type":"entrez-nucleotide","attrs":{"text":"U73122","term_id":"4098075","term_text":"U73122"}}U73122 failed to inhibit several purified PLCs. Most of these PLCs were directly activated by {"type":"entrez-nucleotide","attrs":{"text":"U73122","term_id":"4098075","term_text":"U73122"}}U73122, and a simple mechanism for the activation is proposed. These results strongly suggest a need to re-evaluate the use of {"type":"entrez-nucleotide","attrs":{"text":"U73122","term_id":"4098075","term_text":"U73122"}}U73122 as a general inhibitor of PLC isozymes.
Population biology of Rapana venosa (Valenciennes, 1846) (Gastropoda: Neogastropoda) in the south-eastern Black Sea of Turkey
Creators: name: SAGLAM, Hacer
name: KUTLU, Sebahattin
name: DAGTEKIN, Murat
name: BASCINAR, Selda
name: SAHIN, Ahmet
name: SELEN, Huseyin
name: DUZGUNES, Ertug
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2015

description: The Rapa whelk Rapana venosa is an important commercial gastropod species in Turkey. This paper explains population biology of this species in the aim to ensure the sustainability of this resource. Rapa whelk samples were collected monthly from April 2006 to February 2007 by dredge in the South eastern Black Sea of Turkey (in heavily and lightly exploited areas). The size of whelks ranged 7.56-116.14 mm. The sex ratio F:M is 1:6 in Trabzon and 1:1 in Samsun. The individuals in Samsun region are larger than Trabzon. Female whelks are significantly smaller and lighter than males in both areas. The maximum density was observed to be 12.3 t.km-2 in summer at Samsun. The most by-catch species are blood cockle Anadara inaequivalvis (Bruguière, 1789) and shore crab Liocarcinus depurator (Linnaeus, 1758).
Spin-orbit interaction controlled properties of two-dimensional superlattices: Spintronic crystals
Creators: name: Foldi, Peter
name: Szaszko-Bogar, Viktor
name: Peeters, F. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The band structure of two-dimensional artificial superlattices in the presence of (Rashba-type) spin-orbit interaction (SOI) is presented. The position and shape of the energy bands in these spintronic crystals depend on the geometry as well as the strength of the SOI, which can be tuned by external gate voltages. For finite mesoscopic arrays we show that their conductance properties can be understood from these spin-dependent band diagrams.
description: 5 pages, 4 figures
DJ-1 Enhances Cell Survival through the Binding of Cezanne, a Negative Regulator of NF-κB
Creators: name: Davis, Beckley K.
name: Accavitti-Loper, Mary Ann
name: McNally, R. Sean
name: Clements, Casey M.
name: Mak, Tak W.
name: Ting, Jenny P.Y.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Heightened DJ-1 (Park7) expression is associated with a reduction in chemotherapeutic-induced cell death and poor prognosis in several cancers, whereas the loss of DJ-1 function is found in a subgroup of Parkinson disease associated with neuronal death. This study describes a novel pathway by which DJ-1 modulates cell survival. Mass spectrometry shows that DJ-1 interacts with BBS1, CLCF1, MTREF, and Cezanne/OTUD7B/Za20d1. Among these, Cezanne is a known deubiquitination enzyme that inhibits NF-κB activity. DJ-1/Cezanne interaction is confirmed by co-immunoprecipitation of overexpressed and endogenous proteins, maps to the amino-terminal 70 residues of DJ-1, and leads to the inhibition of the deubiquitinating activity of Cezanne. Microarray profiling of shRNA-transduced cells shows that DJ-1 and Cezanne regulate IL-8 and ICAM-1 expression in opposing directions. Similarly, DJ-1 enhances NF-κB nuclear translocation and cell survival, whereas Cezanne reduces these outcomes. Analysis of mouse Park7−/− primary cells confirms the regulation of ICAM-1 by DJ-1 and Cezanne. As NF-κB is important in cellular survival and transformation, IL-8 functions as an angiogenic factor and pro-survival signal, and ICAM-1 has been implicated in tumor progression, invasion, and metastasis; these data provide an additional modality by which DJ-1 controls cell survival and possibly tumor progression via interaction with Cezanne.
title: Requirements for exterior walls
Creators: name: Hutcheon, N. B.
Publisher: name: National Research Council of Canada. Division of Building Research
Year: 1963
Subjects: subject: Walls
valueUri: urn:ircsubjects:IRC0380
subject: Murs
valueUri: urn:ircsubjects:IRC0380
subject: external envelopes
subject: enveloppe (bâtiment)
subject: walls
subject: mur

description: Durable walls can be achieved by judicious selection of materials to suit the environment, by modification of the environment to suit the materials available, or by a combination of both. Such manipulation, however, requires an understanding of the pertinent properties of materials and the phenomena that operate within walls.
Additional file 2 of Communication of palliative care needs in discharge letters from hospice providers to primary care: a multisite sequential explanatory mixed methods study
Creators: name: Weetman, Katharine
name: Dale, Jeremy
name: Mitchell, Sarah J.
name: Ferguson, Claire
name: Finucane, Anne M.
name: Buckle, Peter
name: Arnold, Elizabeth
name: Clarke, Gemma
name: Karakitsiou, Despoina-Elvira
name: McConnell, Tracey
name: Sanyal, Nikhil
name: Schuberth, Anna
name: Tindle, Georgia
name: Perry, Rachel
name: Grewal, Bhajneek
name: Patynowska, Katarzyna A.
name: MacArtney, John I.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 2. Focus group guide.
title: Endovascular treatment of pulmonary arterial pseudoaneurysm using ONYX® emobolisation: Two successful cases
Creators: name: Ashburner, Graham
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Interventional vascular
subject: Arteries / Aorta
subject: CT-Angiography
subject: Fluoroscopy
subject: Embolisation
subject: Aneurysms

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To provide a basic review of pulmonary artery psuedoaneurysm aetiology To provide a brief review of the methods used to treat pulmonary arterial pseudoaneurysms using an endovascular approach. To show that from our two cases, ONYX is a viable option...
From pulsar scintillations to coronal heating: discontinuities in magnetohydrodynamics
Creators: name: Braithwaite, Jonathan
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: From pulsar scintillations we infer the presence of sheet-like structures in the ISM; it has been suggested that these are current sheets. Current sheets probably play an important role in heating the solar corona, and there is evidence for their presence in the solar wind. Such magnetic discontinuities have been found in numerical simulations with particular boundary conditions, as well as in simulations using an incompressible equation of state. Here, I investigate their formation under more general circumstances by means of topological considerations as well as numerical simulations of the relaxation of an arbitrary smoothly-varying magnetic field. The simulations are performed with a variety of parameters and boundary conditions: in low, high and of-order-unity plasma-$β$ regimes, with periodic and fixed boundaries, with and without a friction force, at various resolutions and with various diffusivities. Current sheets form, over a dynamical timescale, under {\it all} conditions explored. At higher resolution they are thinner, and there is a greater number of weaker current sheets. The magnetic field eventually relaxes into a smooth minimum energy state, the energy of which depends on the magnetic helicity, as well as on the nature of the boundaries.
description: MNRAS accepted. 10 pages, 12 figures. Comments welcome
Reproductive biology of the common stingray Dasyatis pastinaca (Linnaeus, 1758) off the Gulf of Gabès (Central Mediterranean Sea)
Creators: name: SAADAOUI, Abdesselem
name: SAIDI, Béchir
name: ENAJJAR, Samira
name: BRADAI, Mohamed Nejmeddine
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2015

description: This work deals with the reproductive biology of the common stingray, Dasyatis pastinaca, in the Gulf of Gabès (Central Mediterranean Sea). A total of 383 specimens (212 females, 171 males) were collected from bottom trawls, gillnets and longlines between June 2011 and October 2014. The largest male and female measured respectively 47 and 69 cm Disc Width (DW) and weighted 4150 and 12700 g. The Relationships between DW and MT were significantly different between sexes. The DW at which 50% of the population reached maturity was 33 cm and 40 cm respectively for males and females. In females, the oocytes diameter and the gonadosomatic index (GSI) suggest that ovulation occurred during the end of June early July. Pregnant females with fully developed foetuses were captured in June and neonates were observed during the end of June and early July. In males, the GSI values were highest from Mars to May, suggesting that the mating season occurred throughout July. The common stingray, Dasyatis pastinaca, is a slightly prolific species, the fecundity not exceed 10 foetuses per litter. The size at birth ranges from 11.22 to 13.15 cm DW.
Dual Targets for Mouse Mast Cell Protease-4 in Mediating Tissue Damage in Experimental Bullous Pemphigoid
Creators: name: Abrink, Magnus
name: Liu, Zhi
name: Bankaitis, Eric
name: Diaz, Luis A.
name: Heimbach, Lisa
name: Lin, Lan
name: Werb, Zena
name: Pejler, Gunnar
name: Li, Ning
name: An, Lijia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Mouse mast cell protease-4 (mMCP-4) has been linked to autoimmune and inflammatory diseases, although the exact mechanisms underlying its role in these pathological conditions remain unclear. Here, we have found that mMCP-4 is critical in a mouse model of the autoimmune skin blistering disease bullous pemphigoid (BP). Mice lacking mMCP-4 were resistant to experimental BP. Complement activation, mast cell (MC) degranulation, and the early phase of neutrophil (PMN) recruitment occurred comparably in mMCP-4−/− and WT mice. However, without mMCP-4, activation of matrix metalloproteinase (MMP)-9 was impaired in cultured mMCP-4−/− MCs and in the skin of pathogenic IgG-injected mMCP-4−/− mice. MMP-9 activation was not fully restored by local reconstitution with WT or mMCP-4−/− PMNs. Local reconstitution with mMCP-4+/+ MCs, but not with mMCP-4−/− MCs, restored blistering, MMP-9 activation, and PMN recruitment in mMCP-4−/− mice. mMCP-4 also degraded the hemidesmosomal transmembrane protein BP180 both in the skin and in vitro. These results demonstrate that mMCP-4 plays two different roles in the pathogenesis of experimental BP, by both activating MMP-9 and by cleaving BP180, leading to injury of the hemidesmosomes and extracellular matrix of the basement membrane zone.
(3988) Stephanie Boyle/Ramsay
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Endogenous Myoglobin in Breast Cancer Is Hypoxia-inducible by Alternative Transcription and Functions to Impair Mitochondrial Activity: A ROLE IN TUMOR SUPPRESSION?
Creators: name: Varia, Mahesh A.
name: Stiehl, Daniel P.
name: Subarsky, Patrick
name: Moch, Holger
name: Hu, Junmin
name: Gerhardt, Josefine
name: Dahl, Edgar
name: Raleigh, James
name: Gassmann, Max
name: Gnaiger, Erich
name: Gleixner, Eva
name: Kristiansen, Glen
name: Hankeln, Thomas
name: Ten Haaf, Anette
name: Wichmann, Daniela
name: Rose, Michael
name: Bicker, Anne
name: Gorr, Thomas A.
name: Scandurra, Francesca M.
name: Bohnert, Annette
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Recently, immunohistochemical analysis of myoglobin (MB) in human breast cancer specimens has revealed a surprisingly widespread expression of MB in this nonmuscle context. The positive correlation with hypoxia-inducible factor 2α (HIF-2α) and carbonic anhydrase IX suggested that oxygen regulates myoglobin expression in breast carcinomas. Here, we report that MB mRNA and protein levels are robustly induced by prolonged hypoxia in breast cancer cell lines, in part via HIF-1/2-dependent transactivation. The hypoxia-induced MB mRNA originated from a novel alternative transcription start site 6 kb upstream of the ATG codon. MB regulation in normal and tumor tissue may thus be fundamentally different. Functionally, the knockdown of MB in MDA-MB468 breast cancer cells resulted in an unexpected increase of O2 uptake and elevated activities of mitochondrial enzymes during hypoxia. Silencing of MB transcription attenuated proliferation rates and motility capacities of hypoxic cancer cells and, surprisingly, also fully oxygenated breast cancer cells. Endogenous MB in cancer cells is apparently involved in controlling oxidative cell energy metabolism, contrary to earlier findings on mouse heart, where the targeted disruption of the Mb gene did not effect myocardial energetics and O2 consumption. This control function of MB seemingly impacts mitochondria and influences cell proliferation and motility, but it does so in ways not directly related to the facilitated diffusion or storage of O2. Hypothetically, the mitochondrion-impairing role of MB in hypoxic cancer cells is part of a novel tumor-suppressive function.
Large-scale mass distribution in the Illustris simulation
Creators: name: Haider, Markus
name: Steinhauser, Dominik
name: Vogelsberger, Mark
name: Genel, Shy
name: Springel, Volker
name: Torrey, Paul
name: Hernquist, Lars
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Observations at low redshifts thus far fail to account for all of the baryons expected in the Universe according to cosmological constraints. A large fraction of the baryons presumably resides in a thin and warm-hot medium between the galaxies, where they are difficult to observe due to their low densities and high temperatures. Cosmological simulations of structure formation can be used to verify this picture and provide quantitative predictions for the distribution of mass in different large-scale structure components. Here we study the distribution of baryons and dark matter at different epochs using data from the Illustris simulation. We identify regions of different dark matter density with the primary constituents of large-scale structure, allowing us to measure mass and volume of haloes, filaments and voids. At redshift zero, we find that 49 % of the dark matter and 23 % of the baryons are within haloes more massive than the resolution limit of $2\times 10^8$ M$_\odot$. The filaments of the cosmic web host a further 45 % of the dark matter and 46 % of the baryons. The remaining 31 % of the baryons reside in voids. The majority of these baryons have been transported there through active galactic nuclei feedback. We note that the feedback model of Illustris is too strong for heavy haloes, therefore it is likely that we are overestimating this amount. Categorizing the baryons according to their density and temperature, we find that 17.8 % of them are in a condensed state, 21.6 % are present as cold, diffuse gas, and 53.9 % are found in the state of a warm-hot intergalactic medium.
description: 12 pages, 15 figures
(3989) William Sym
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(3990) Christina Laurie
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Toitures en terrasse
Creators: name: Baker, M. C.
Publisher: name: Conseil national de recherches du Canada. Division des recherches en construction
Year: 1963
Subjects: subject: Roofs
valueUri: urn:ircsubjects:IRC0370
subject: Toitures
valueUri: urn:ircsubjects:IRC0370
subject: roofing
subject: couvertures
subject: built up roofings
subject: multicouche
subject: durability
subject: durabilité
subject: flat roofs
subject: toiture en terrasse

description: Le but du présent Digeste est d'indiquer les principaux facteurs dont il faut tenir compte dans l'établissement des plans et dans la construction des toitures en terrasse, étant entendu qu'il s'agit ici de toitures à couches de bitume recouvertes de graviers qu'on applique "à chaud" sur des toits plats ou presque plats.
Additional file 3 of Communication of palliative care needs in discharge letters from hospice providers to primary care: a multisite sequential explanatory mixed methods study
Creators: name: Weetman, Katharine
name: Dale, Jeremy
name: Mitchell, Sarah J.
name: Ferguson, Claire
name: Finucane, Anne M.
name: Buckle, Peter
name: Arnold, Elizabeth
name: Clarke, Gemma
name: Karakitsiou, Despoina-Elvira
name: McConnell, Tracey
name: Sanyal, Nikhil
name: Schuberth, Anna
name: Tindle, Georgia
name: Perry, Rachel
name: Grewal, Bhajneek
name: Patynowska, Katarzyna A.
name: MacArtney, John I.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 3. GRAMMS checklist.
Peak locations and relative phase of different decay modes of the $a_1$ axial vector resonance in diffractive production
Creators: name: Basdevant, Jean-Louis
name: Berger, Edmond L
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We show that a single $I=1$ spin-parity $J^{PC}= 1^{++}$ $a_1$ resonance can manifest itself as two separated mass peaks, one decaying into an S-wave $ρπ$ system and the second decaying into a P-wave $f_0(980)π$ system, with a rapid increase of the phase difference between their amplitudes arising mainly from the structure of the diffractive production process. This study clarifies questions related to the mass, width, and decay rates of the $a_1$ resonance raised by the recent high statistics data of the COMPASS collaboration on $a_1$ production in $πN \rightarrow πππN$ at high energies.
description: 4 pages, 4 figures, to be published in Physical Review Letters. arXiv admin note: substantial text overlap with arXiv:1501.04643
FAUNISTIC INVENTORY AND ECOLOGICAL AND BIONOMIC CHARACTERIZATION OF THE POLYCHAETE ANNELIDS OF MAR-MENOR (SE SPAIN)
Creators: name: Azzati, R. C.
name: Carrascosa, M. G.
name: Babio, C. R.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1987

Abstract
title: Causes for poor image quality in CTCA – a single institute study
Creators: name: Harvey, James
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Artifacts
subject: Arteriosclerosis
subject: Diagnostic procedure
subject: CT-Angiography
subject: Mediastinum
subject: Cardiovascular system
subject: Cardiac

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Computer tomography coronary angiography (CTCA) is increasingly employed due to its diagnostic accuracy and minimally invasive nature. 1 The high negative predictor value makes CTCA useful in excluding clinically significant coronary artery disease....
Agonists of gonadotropin releasing hormone (GnRHa) pellets implantation in Seriola dumerili (Risso, 1810) under water temperature variations
Creators: name: PICCIONE, Giuseppe
name: SCOPITTERI, Teresa
name: PERILLO, Laura
name: GIANNETTO, Claudia
name: FORTINO, Gianluca
name: LAURÀ, Rosaria
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2015

description: The aim of the present study was to enhance the current knowledge on reproduction of Mediterranean greater amberjack (Seriola dumerili) in aquaculture and evaluate the influence of temperature variations on the sexual cycle. Fifteen Seriola dumerili (6 males and 9 females) were enrolled in the study. The animals were randomly divided in two groups: experimental group (n = 8) and control group (n = 7). Before experimental trial starts, biopsies from each fish were performed in order to establish gonadal maturation state. Afterwards, spawning was stimulated in experimental group through the agonists of gonadotropin releasing hormone (GnRHa) implants. No spawning events were observed in experimental group neither in control group during the week after experimental trial. The water temperature control showed a variation of about two degrees between the fourth and the sixth day after implantation. A week after experiment, a second gonadal biopsy was executed showing a gonadal regression in female subjects of both groups and an increase in sperm production of male subjects of experimental group. The study underlines the influence of water temperature variation on fish reproduction, in particular in females, even if GnRHa implants were used to stimulate spawning.
Additional file 4 of Communication of palliative care needs in discharge letters from hospice providers to primary care: a multisite sequential explanatory mixed methods study
Creators: name: Weetman, Katharine
name: Dale, Jeremy
name: Mitchell, Sarah J.
name: Ferguson, Claire
name: Finucane, Anne M.
name: Buckle, Peter
name: Arnold, Elizabeth
name: Clarke, Gemma
name: Karakitsiou, Despoina-Elvira
name: McConnell, Tracey
name: Sanyal, Nikhil
name: Schuberth, Anna
name: Tindle, Georgia
name: Perry, Rachel
name: Grewal, Bhajneek
name: Patynowska, Katarzyna A.
name: MacArtney, John I.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 4. Aggregated special category data.
title: Finition des dalles de béton
Creators: name: Dickens, H. B.
Publisher: name: Conseil national de recherches du Canada. Division des recherches en construction
Year: 1963
Subjects: subject: Concrete
valueUri: urn:ircsubjects:IRC0740
subject: Béton
valueUri: urn:ircsubjects:IRC0740
subject: exposed concrete finishes
subject: surfacage du béton apparent
subject: industrial facilities
subject: installation industrielle
subject: floor coverings
subject: revêtement de sol
subject: flat slab floors
subject: plancher dalle
subject: concrete pavement
subject: dallage en béton

description: On considère dans le présent digeste les facteurs qui affectent la qualité de la finition des dalles de béton. Des renseignements sont également donnés quant aux meilleures facons d'apprêter les sols de béton. On sait par expérience que la plupart des ruptures sont attribuables à des plans mal faits ou à des constructions peu soignées et qu'il aurait été possible de les éviter en faisant bien attention aux facteurs qui sont à la base d'une installation de qualité.
Neighborhood disadvantage and immune-related illnesses among residents living in the US Gulf States
Creators: name: Engel, L.S.
name: Lawrence, K.G.
name: Parks, C.G.
name: Jackson, W.B., III
name: Patel, O.P.
name: Bodkin, M.
name: Sandler, D.P.
Publisher: name: Elsevier Inc.
Year: 2023

description: Purpose: Neighborhood disadvantage has been associated with increased risk for pneumonia and influenza-associated hospitalizations. Few studies, however, have investigated how neighborhood disadvantage may influence immune-related illnesses. The aim of this study was to examine the association between neighborhooddisadvantage and immune-related illnesses. Methods: We used data from the Gulf Long-term Follow-up (GuLF) Study (n = 32,608). Our analytic sample included home visit participants (n = 11,193) who had complete information on exposure and covariates (n = 10,543). Neighborhood disadvantage was assessed using the 2013 Area Deprivation Index (ADI), which assigns a ranking of 1 to 100 for lowest to highest disadvantage. We linked ADI to participants’ geocoded enrollment addresses at the census block group level. ADI was categorized into quartiles based on the national distribution with the first quartile as the referent. Immune-related illnesses self-reported at the home visit (May 2011–May 2013) included occurrence of shingles, pneumonia, cold sores, flu, and colds since the Deepwater Horizon oil spill (April 2010). Frequent colds and frequent flu were defined as ≥4 colds and ≥2 episodes of flu since the spill. An aggregated outcome, based on occurrence of any pneumonia, cold sores, flu, and ≥4 colds since the spill, was also examined. We assessed the association of each outcome with ADI using multivariable log-binomial regression adjusting for individual-level demographics, behavioral factors, kids at home, and season of interview completion. Results: We found elevated prevalence ratios (PR) and 95% confidence intervals (CI) for pneumonia associated with ADI in the third (PR: 2.04, 95% CI: 1.04, 4.02) and fourth (PR: 2.00; 95% CI: 1.00, 3.98) quartiles. PRs for frequent colds were also elevated for increasing ADI quartiles, but with confidence intervals including the null value. Conclusions: The observed associations of frequent colds and pneumonia with increasing neighborhood disadvantage may warrant further research on this topic
Картографирование древостоя старовозрастного широколиственного леса по материалам зимней аэрофотосъемки с помощью квадрокопрера
Creators: name: Shashkov, Maxim
name: Ivanova, Natalya
Publisher: name: Zenodo
Year: 2020

description: Сбор полевого материала проведен на постоянной пробной площади в заповеднике "Калужские Засеки" в 2017-18 гг. На основе материалов зимней аэрофотосъемки разработана оригинальная методика определения координат комлей деревьев для построения плана древостоя. Для оценки результата работы требуется полевая верификация.
title: Comparing the efficacy of Active Breathing Coordinator and Voluntary Breath Hold in Deep Inspiration Breath Hold Breast Cancer Radiotherapy
Creators: name: Parasuramar, Amaran
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Breast
subject: Radioprotection / Radiation dose
subject: Cardiac
subject: CT
subject: CT-High Resolution
subject: Radiation therapy / Oncology
subject: Complications
subject: Radiation effects
subject: Cancer
subject: Dosimetric comparison
subject: Image guided radiotherapy

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Breast cancer remains the most common cancer to target women in Australia (1). Adjuvant radiotherapy (RT) has become the mainstay treatment after breast conserving surgery for invasive cancer and post-mastectomy radiotherapy, boasting a reduction of...
title: Ten histologic patterns every neuroradiologist should know
Creators: name: Lekgabe, Ernest
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Pathology
subject: Neoplasia
subject: Education
subject: MR
subject: CNS

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To become familiar with ten important neuropathology histological patterns and understand (a) how they relate to histological diagnosis of various CNS tumours and (b) how they may manifest on...
(3986) Robert Brennan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Source-independent quantum random number generation
Creators: name: Cao, Zhu
name: Zhou, Hongyi
name: Yuan, Xiao
name: Ma, Xiongfeng
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum random number generators can provide genuine randomness by appealing to the fundamental principles of quantum mechanics. In general, a physical generator contains two parts---a randomness source and its readout. The source is essential to the quality of the resulting random numbers; hence, it needs to be carefully calibrated and modeled to achieve information-theoretical provable randomness. However, in practice, the source is a complicated physical system, such as a light source or an atomic ensemble, and any deviations in the real-life implementation from the theoretical model may affect the randomness of the output. To close this gap, we propose a source-independent scheme for quantum random number generation in which output randomness can be certified, even when the source is uncharacterized and untrusted. In our randomness analysis, we make no assumptions about the dimension of the source. For instance, multiphoton emissions are allowed in optical implementations. Our analysis takes into account the finite-key effect with the composable security definition. In the limit of large data size, the length of the input random seed is exponentially small compared to that of the output random bit. In addition, by modifying a quantum key distribution system, we experimentally demonstrate our scheme and achieve a randomness generation rate of over $5\times 10^3$ bit/s.
description: 11 pages, 7 figures
(3987) Mary Ann Hammond
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 5 of Communication of palliative care needs in discharge letters from hospice providers to primary care: a multisite sequential explanatory mixed methods study
Creators: name: Weetman, Katharine
name: Dale, Jeremy
name: Mitchell, Sarah J.
name: Ferguson, Claire
name: Finucane, Anne M.
name: Buckle, Peter
name: Arnold, Elizabeth
name: Clarke, Gemma
name: Karakitsiou, Despoina-Elvira
name: McConnell, Tracey
name: Sanyal, Nikhil
name: Schuberth, Anna
name: Tindle, Georgia
name: Perry, Rachel
name: Grewal, Bhajneek
name: Patynowska, Katarzyna A.
name: MacArtney, John I.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 5. Corpus linguistics outputs.
title: Developing knowledge-based planning for gynaecological cancer: A retrospective dosimetric validation study of Rapidplan
Creators: name: Shepherd, Meegan
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Genital / Reproductive system female
subject: CT
subject: Radiation therapy / Oncology
subject: VMAT and Tomotherapy
subject: Cancer
subject: Radiotherapy techniques
subject: Dosimetric comparison

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: The use of Radiation Therapy (RT) for cancers of the endometrium and uterine cervix has been shown to lower the risk of cancer recurrence and death [1-4]. Comparisons of pelvic RT performed with Intensity Modulated Radiation Therapy (IMRT) and...
Dipolar dynamos in stratified systems
Creators: name: Raynaud, R.
name: Petitdemange, L.
name: Dormy, E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Observations of low-mass stars reveal a variety of magnetic field topologies ranging from large-scale, axial dipoles to more complex magnetic fields. At the same time, three-dimensional spherical simulations of convectively driven dynamos reproduce a similar diversity, which is commonly obtained either with Boussinesq models or with more realistic models based on the anelastic approximation, which take into account the variation of the density with depth throughout the convection zone. Nevertheless, a conclusion from different anelastic studies is that dipolar solutions seem more difficult to obtain as soon as substantial stratifications are considered. In this paper, we aim at clarifying this point by investigating in more detail the influence of the density stratification on dipolar dynamos. To that end, we rely on a systematic parameter study that allows us to clearly follow the evolution of the stability domain of the dipolar branch as the density stratification is increased. The impact of the density stratification both on the dynamo onset and the dipole collapse is discussed and compared to previous Boussinesq results. Furthermore, our study indicates that the loss of the dipolar branch does not ensue from a specific modification of the dynamo mechanisms related to the background stratification, but could instead result from a bias as our observations naturally favour a certain domain in the parameter space characterized by moderate values of the Ekman number, owing to current computational limitations. Moreover, we also show that the critical magnetic Reynolds number of the dipolar branch is scarcely modified by the increase of the density stratification, which provides an important insight into the global understanding of the impact of the density stratification on the stability domain of the dipolar dynamo branch.
Expanding the distribution of the Aquificales to the deep-sea
vents on Mid-Atlantic Ridge and Central Indian Ridge
Creators: name: REYSENBACH, Anna-Louise
name: GÖTZ, Dorothee
name: BANTA, Amy
name: JEANTHON, Christian
name: FOUQUET, Yves
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2002

Abstract
Evidence for a spectroscopic direct detection of reflected light from 51 Peg b
Creators: name: Martins, J. H. C.
name: Santos, N. C.
name: Figueira, P.
name: Faria, J. P.
name: Montalto, M.
name: Boisse, I.
name: Ehrenreich, D.
name: Lovis, C.
name: Mayor, M.
name: Melo, C.
name: Pepe, F.
name: Sousa, S. G.
name: Udry, S.
name: Cunha, D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The detection of reflected light from an exoplanet is a difficult technical challenge at optical wavelengths. Even though this signal is expected to replicate the stellar signal, not only is it several orders of magnitude fainter, but it is also hidden among the stellar noise. We apply a variant of the cross-correlation technique to HARPS observations of 51 Peg to detect the reflected signal from planet 51 Peg b. Our method makes use of the cross-correlation function of a binary mask with high-resolution spectra to amplify the minute planetary signal that is present in the spectra by a factor proportional to the number of spectral lines when performing the cross correlation. The resulting cross-correlation functions are then normalized by a stellar template to remove the stellar signal. Carefully selected sections of the resulting normalized CCFs are stacked to increase the planetary signal further. The recovered signal allows probing several of the planetary properties, including its real mass and albedo. We detect evidence for the reflected signal from planet 51 Peg b at a significance of 3σ_noise. The detection of the signal permits us to infer a real mass of 0.46^+0.06_-0.01 M_Jup (assuming a stellar mass of 1.04\;M_Sun) for the planet and an orbital inclination of 80^+10_-19 degrees. The analysis of the data also allows us to infer a tentative value for the (radius-dependent) geometric albedo of the planet. The results suggest that 51Peg b may be an inflated hot Jupiter with a high albedo (e.g., an albedo of 0.5 yields a radius of 1.9 \pm 0.3 R_Jup for a signal amplitude of 6.0\pm0.4 x 10^-5). We confirm that the method we perfected can be used to retrieve an exoplanet's reflected signal, even with current observing facilities. The advent of next generation of observing facilities will yield new opportunities for this type of technique to probe deeper into exoplanets.
description: 9 pages, 6 figures
(3985) Agnes [Brennan]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 6 of Communication of palliative care needs in discharge letters from hospice providers to primary care: a multisite sequential explanatory mixed methods study
Creators: name: Weetman, Katharine
name: Dale, Jeremy
name: Mitchell, Sarah J.
name: Ferguson, Claire
name: Finucane, Anne M.
name: Buckle, Peter
name: Arnold, Elizabeth
name: Clarke, Gemma
name: Karakitsiou, Despoina-Elvira
name: McConnell, Tracey
name: Sanyal, Nikhil
name: Schuberth, Anna
name: Tindle, Georgia
name: Perry, Rachel
name: Grewal, Bhajneek
name: Patynowska, Katarzyna A.
name: MacArtney, John I.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 6. Data extraction results.
Enhancement of the Rate of Pyrophosphate Hydrolysis by Nonenzymatic Catalysts and by Inorganic Pyrophosphatase
Creators: name: Stockbridge, Randy B.
name: Wolfenden, Richard
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: To estimate the proficiency of inorganic pyrophosphatase as a catalyst, 31P NMR was used to determine rate constants and thermodynamics of activation for the spontaneous hydrolysis of inorganic pyrophosphate (PPi) in the presence and absence of Mg2+ at elevated temperatures. These values were compared with rate constants and activation parameters determined for the reaction catalyzed by Escherichia coli inorganic pyrophosphatase using isothermal titration calorimetry. At 25 °C and pH 8.5, the hydrolysis of MgPPi2− proceeds with a rate constant of 2.8 × 10−10 s−1, whereas E. coli pyrophosphatase was found to have a turnover number of 570 s−1 under the same conditions. The resulting rate enhancement (2 × 1012-fold) is achieved entirely by reducing the enthalpy of activation (ΔΔH‡ = −16.6 kcal/mol). The presence of Mg2+ ions or the transfer of the substrate from bulk water to dimethyl sulfoxide was found to increase the rate of pyrophosphate hydrolysis by as much as ∼106-fold. Transfer to dimethyl sulfoxide accelerated PPi hydrolysis by reducing the enthalpy of activation. Mg2+ increased the rate of PPi hydrolysis by both increasing the entropy of activation and reducing the enthalpy of activation.