The Role of KRAS rs61764370 in Invasive Epithelial Ovarian Cancer: Implications for Clinical Testing
Creators: name: Lindblom, Annika
name: Flanagan, James M.
name: Anton-Culver, Hoda
name: Goode, Ellen L.
name: Brewster, Wendy
name: Dürst, Matthias
name: Chenevix-Trench, Georgia
name: LaPolla, James P.
name: Eccles, Diana M.
name: Terry, Kathryn L.
name: Walsh, Christine
name: Nedergaard, Lotte
name: Antonenkova, Natalia
name: Kaye, Stanley B.
name: Ziogas, Argyrios
name: Caldes, Trinidad
name: Wang-Gohrke, Shan
name: Couch, Fergus J.
name: Heikkinen, Tuomas
name: Beattie, Mary S.
name: Kjaer, Susanne Krüger
name: Gayther, Simon A.
name: Schildkraut, Joellen M.
name: Singer, Christian F.
name: Tsai, Ya Yu
name: Rookus, Matti
name: Leunen, Karin
name: Massuger, Leon F.
name: Nickels, Stefan
name: Caligo, Maria Adelaide
name: Stram, Daniel O.
name: Despierre, Evelyn
name: Wappenschmidt, Barbara
name: Lázaro, Conxi
name: Risch, Harvey A.
name: Harnett, Paul
name: Levine, Douglas A.
name: Campbell, Ian
name: Pike, Malcolm C.
name: Phelan, Catherine M.
name: McLaughlin, John R.
name: Vitonis, Allison F.
name: Gentry-Maharaj, Aleksandra
name: Goldgar, David
name: Rossing, Mary Anne
name: Godwin, Andrew K.
name: Dörk, Thilo
name: Ramus, Susan J.
name: Goodman, Marc T.
name: Antoniou, Antonis C.
name: Høgdall, Claus
name: Doherty, Jennifer A.
name: Fasching, Peter A.
name: Sutphen, Rebecca
name: Bolton, Kelly L.
name: Macgregor, Stuart
name: Palmieri, Rachel T.
name: Chang-Claude, Jenny
name: Wu, Anna H.
name: Cramer, Daniel W.
name: Kiemeney, Lambertus A.
name: Song, Honglin
name: Narod, Steven A.
name: Vergote, Ignace
name: Menon, Usha
name: Kauff, Noah D.
name: Birrer, Michael J.
name: Ekici, Arif B.
name: Nathanson, Katherine L.
name: Marees, Tamara
name: Pearce, Celeste Leigh
name: Friedman, Eitan
name: Radice, Paolo
name: Ness, Roberta B.
name: Van Altena, Anne M.
name: Karlan, Beth Y.
name: Brooks-Wilson, Angela
name: Fridley, Brooke L.
name: Andrulis, Irene L.
name: Lambrechts, Diether
name: Osorio, Ana
name: Cook, Linda S.
name: Le, Nhu D.
name: Leminen, Arto
name: Gao, Bo
name: De Fazio, Anna
name: Kelemen, Linda E.
name: Lundvall, Lene
name: Hein, Rebecca
name: Paul, Jim
name: Iversen, Edwin S.
name: Fenstermacher, David A.
name: Jakubowska, Anna
name: Høgdall, Estrid
name: Nevanlinna, Heli
name: Chen, Y. Ann
name: Bogdanova, Natalia
name: Moysich, Kirsten B.
name: Montagna, Marco
name: Cunningham, Julie M.
name: Sellers, Thomas A.
name: Berchuck, Andrew
name: Butzow, Ralf
name: Brown, Robert
name: Sinilnikova, Olga
name: Gross, Jenny
name: Hansen, Thomas V.O.
name: Johnatty, Sharon E.
name: Vierkant, Robert A.
name: Beckmann, Matthias W.
name: Pharoah, Paul D.P.
name: Easton, Douglas
name: Lu, Yi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: An assay for the single nucleotide polymorphism (SNP) rs61764370 has recently been commercially marketed as a clinical test to aid ovarian cancer risk evaluation in women with family histories of the disease. rs67164370 is in a 3′UTR miRNA binding site of the KRAS oncogene, and is a candidate for epithelial ovarian cancer (EOC) susceptibility. However, only one published paper, analyzing fewer than 1,000 subjects in total, has examined this association.