cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
PRO-based follow-up as a means of self-management support – an interpretive description of the patient perspective
Creators: name: Mejdahl, Caroline T.
name: Schougaard, Liv M. V.
name: Hjollund, Niels H.
name: Riiskjær, Erik
name: Thorne, Sally E. (Sally Elizabeth), 1951-
name: Lomborg, Kirsten
Publisher: name: Springer International Publishing
Year: 2018

description: Background: There is an increasing focus on the use of patient-reported outcome (PRO) measures to improve the quality and effectiveness of health care. PRO-based follow-up is a new model of service delivery, where the patient’s PRO measures are used as the very basis for outpatient follow-up. Objectives: This study aimed to explore how patients with epilepsy experience the use of PRO-based follow-up in three outpatient clinics in the Central Denmark Region. We also sought to explain how these experiences relate to self-management. Methods: Interpretive description was the methodological approach. We conducted in-depth individual interviews with 29 patients referred to PRO-based follow-up, each of whom had completed at least two PRO questionnaires. Participants were sampled based on purposive and theoretical sampling. Results: PRO-based follow-up may support patients’ self-management by a) increasing awareness of psychosocial problems, b) improving communication, c) increasing understanding of symptoms, d) facilitating change in health behavior and e) strengthening autonomy. Inhibitors for PRO measures as a means of self-management support were identified as a) feelings of rejection and disconnection, b) incomprehension of purpose of PRO-based follow-up, c) PRO measures being too standardized and negative and d) lack of confidence in own ability to assess PRO questionnaires. Conclusion: The findings demonstrate broad variation in the influences of PRO measures on patient’s self-management in life with epilepsy. Sense of ownership may explain this variation. We suggest supplementary clinical initiatives in order to enhance the benefits from PRO-based follow-up, particularly on how patients are allocated to this health care service.
Identification and Characterization of Circular RNAs As a New Class of Putative Biomarkers in Human Blood
Creators: name: Memczak, Sebastian
name: Papavasileiou, Panagiotis
name: Peters, Oliver
name: Rajewsky, Nikolaus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie

description: Covalently closed circular RNA molecules (circRNAs) have recently emerged as a class of RNA isoforms with widespread and tissue specific expression across animals, oftentimes independent of the corresponding linear mRNAs. circRNAs are remarkably stable and sometimes highly expressed molecules. Here, we sequenced RNA in human peripheral whole blood to determine the potential of circRNAs as biomarkers in an easily accessible body fluid. We report the reproducible detection of thousands of circRNAs. Importantly, we observed that hundreds of circRNAs are much higher expressed than corresponding linear mRNAs. Thus, circRNA expression in human blood reveals and quantifies the activity of hundreds of coding genes not accessible by classical mRNA specific assays. Our findings suggest that circRNAs could be used as biomarker molecules in standard clinical blood samples.
Formation, characterization, and performance testing of poly(phenylene oxide) and modified poly(phenylene oxide) membranes for gas separation
Creators: name: Hamad, Feras
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Engineering, Chemical.

description: This work was focused on gas separation membranes made from high molecular weight poly (2,6-dimethyl-1,4-phenyl oxide) (PPO) and its chemically modified derivatives. The molecular weight of the polymer was calculated to be 316400 g/mol corresponding to 1.57 dL/g intrinsic viscosity in chloroform. The research objectives are to (i) study the effect of chemical modification of PPO on the gas separation performance of membranes made from the resulting polymers; (ii) study and compare the formation of dense and composite membranes based on PPO, and correlate the formation of these membranes to their performance and morphology; (iii) put forward a model to predict and evaluate the performance of composite membranes based on the intrinsic properties of the individual polymeric layers forming the composite membrane. The objectives of the research covered the following topics of membrane science: (i) material development and modification, (ii) membrane-gas penetrant interaction, (iii) membrane morphology and formation, and (iv) mathematical modeling of transport phenomena in porous and thin film composite membranes. The gas separation performance of the membranes was tested based on the permeation of CO2, CH4, O2, and N2 gases. The membrane selectivity was mainly judged by CO2/CH4 and O2/N2 permeability ratios. These gases are of relevant industrial and/or environmental interest. The chemical modification of PPO was carried out via sulfonation, bromination, and simultaneous sulfonation and bromination. The gas permeability in 20% and 37.4% brominated PPO membranes increased slightly, while it increased significantly in 60% brominated PPO, in comparison to that of the parent polymer. The permeability ratio of PPO was maintained in the resulting brominated PPO. Infrared study showed that bromination resulted in stiffening the torsional motion of the phenyl ring around the ether link, and at moderate and high bromination levels, the interference of the bromine group with neighboring methyl groups became significant. This conformed to the postulation that high bromination level is needed to produce significant increase in the length of a diffusional jump segment, hence the diffusional jumps rate. The effect of sulfonation of PPO, and the effect of replacing the proton of the sulfonic groups with: mono-valent, di-valent, and tri-valent metal cations, was investigated. (Abstract shortened by UMI.)
Efficacy and safety of non-invasive respiratory support in neonates
Creators: name: Fischer, Hendrik
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: bronchopulmonary dysplasia
subject: continuous positive airway pressure
subject: heated humidification
subject: infant
subject: high-frequency oscillatory ventilation
subject: leak
subject: prematurity
subject: surfactant
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Non-invasive respiratory support is nowadays a mainstay of treatment in neonates with respiratory failure. Established treatment options such as nasal continuous positive airway pressure (CPAP) have been refined over the years. More innovative strategies of non-invasive respiratory support are evolving, but quite often there is a paucity of evidence to support their use. The present habilitation thesis applied different methodologies to address specific research questions relating to the efficacy and safety of these new approaches. In a meta-analysis of randomized controlled trials, we showed that non-invasive respiratory support strategies to avoid endotracheal mechanical ventilation reduced the incidence of death or bronchopulmonary dysplasia without increasing intraventricular hemorrhage in preterm infants of <30 weeks’ gestational age. In a clinical crossover study, we investigated the impact of experimental leak reduction in 32 neonates on nasopharyngeal CPAP but detected only minor beneficial effects on oxygenation. In an international survey, we gained insights about the current clinical use of nasal high-frequency oscillatory ventilation (nHFOV) in tertiary neonatal units. We encountered a great variety of clinical practices and identified upper airway obstruction due to highly viscous secretions as a specific adverse effect of nHFOV. In a dedicated neonatal bench model, we further investigated the determinants of oropharyngeal gas conditions during non-invasive respiratory support. A bench study during nasal CPAP showed that mouth opening reduced oropharyngeal temperature and absolute humidity, even during heated humidification. A second bench study showed that nHFOV additionally impaired oropharyngeal gas conditions and that the magnitude of this effect depended on the ventilatory settings of nHFOV. The implications of the study results on current clinical care and on future research are discussed.
title: Diagnóstico diferencial entre los tumores gliales de alto grado y las metástasis cerebrales solitarias mediante el uso del tensor de difusión y perfusión.
Creators: name: Gongora Lencina, Teresa
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neoplasia
subject: Metastases
subject: MR-Functional imaging
subject: MR-Diffusion/Perfusion
subject: MR
subject: Oncology
subject: Neuroradiology brain

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Los tumores gliales de alto grado y las metástasis cerebrales solitarias pueden tener un patrón de realce similar en las imágenes de RM convencional,
por lo que su diagnóstico diferencial plantea dificultad. El propósito de este estudio es...
Product Development in Science: a collaborative framework to develop university technology towards commercialisation
Creators: name: Mesa Saldarriaga, David
Publisher: name: Swinburne
Year: 2024

description: Although extensive resources are spent each year on university scientific research, the migration of this knowledge to the market remains low; only a few university research projects manage to generate the expected impact on nations' economies. This thesis proposes a framework that combines best practices from technology innovation management and product development to steer university scientific research projects towards commercialisation. A case study of a collaboration between designers and scientists showed several contributions of utilising such a framework, mainly in the early recognition of commercial opportunities for new technologies and creating market-oriented technology demonstrators.
Pour la modernité de la littérature chinoise: Du rapport entre Zola, Mao Dun et Ba Jin
Creators: name: Li, Changshun
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Literature, Comparative.
subject: Literature, Asian.
subject: Literature, Romance.

description: En Chine, le Mouvement du 4 mai 1919 entraîne une métamorphose de la littérature classique chinoise qui acquiert, alors, sa forme moderne sous l'impulsion de ses contacts avec la littérature occidentale. Mao Dun et Ba Jin, écrivains issus de ce mouvement, contribuent à cette transformation par leurs théories et leurs oeuvres littéraires influencées par leurs rencontres avec la littérature occidentale représentée, ici, surtout par le naturalisme d'Émile Zola. Aussi, est-ce avec les parutions, entre autres, des romans Minuit et L'Arc-en-ciel de Mao Dun et Famille de Ba Jin que le roman chinois s'inscrit dans la modernité. Le naturalisme, en tant que courant littéraire international du XIXeme siècle, a connu une grande diffusion en Chine au début des années vingt du XXe siècle, grâce aux essais de Mao Dun visant a présenter le naturalisme de Zola. La propagation du naturalisme constitue une partie importante de la théorie de Mao Dun en vue de construire une nouvelle littérature chinoise. Quant à Ba Jin, sa lecture systématique des Rougon-Macquart de Zola, lors de ses études en France, constitue une composante importante de sa formation littéraire. La présente étude porte sur la représentation des idéologies et des réalités sociales de deux époques en France et en Chine par Zola, Mao Dun et Ba Jin à travers une analyse théorique, esthétique, textuelle et narratologique. C'est en nous référant au naturalisme, en particulier les Rougon-Macquart de Zola, que nous réfléchissons sur la littérature chinoise moderne, à savoir comment Mao Dun et Ba Jin lisent Zola, l'acceptent, le rejettent et le reconstruisent pour faire accéder la littérature chinoise à la modernité. Ainsi avons-nous mis en lumière les progrès, les détours et les limites du développement de la littérature chinoise moderne née au carrefour de sa rencontre avec les littératures française et occidentale dans les 80 premières années du XXe siècle.
Supplementary document for Multi-focus off-axis zone plates for X-ray free-electron laser experiments - 4693976.pdf
Creators: name: Döring, Florian
name: Rösner, Benedikt
name: Langer, Manuel
name: kubec, adam
name: kleibert, armin
name: Raabe, Jörg
name: Vaz, Carlos
name: Lebugle, Maxime
name: David, Christian
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: mathematical derivations
Supplementary document for Nanostructured optical waveguide with a highly confined mode - 4695232.pdf
Creators: name: Chubchev, Eugene
name: Nechepurenko, Igor
name: Dorofeenko, A
name: Vinogradov, Alexey
name: Lisyansky, Alexander
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: In this Supplemental Document, the full set of the equations for the field components in the core, cladding, and outer medium is provided.
Regelungstechnik 2: Zeitdiskrete und zeitkontinuierliche, nichtlineare und optimale Regelungen
Creators: name: Danzer, Michael A.
name: Rauh, Andreas
name: Hofer, Eberhard P.
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Optimale Regelung
subject: DDC 620 / Engineering & allied operations
subject: Control theory
subject: Digitale Regelung
subject: Nichtlineare Regelung
subject: Optimalwertregelung
subject: Regelungstechnik

description: Der erste Teil der Vorlesung Regelungstechnik II umfasst die Behandlung zeitdiskreter Systeme. Hierbei werden insbesondere die Querverbindungen zu linearen zeitkontinuierlichen Systemen betont und bereits bekannte Entwurfsverfahren, die auf Zustandsraummethoden basieren, auf den zeitdiskreten Fall übertragen. Der zweite Teil der Vorlesung ist den nichtlinearen Systemen gewidmet. Schwerpunktmäßig werden nichtlineare Systeme in Zustandsraumdarstellung betrachtet. Dabei sollen auf Basis grundlegender struktureller Systemeigenschaften geeignete Reglerentwurfsverfahren abgeleitet werden. Die für nichtlineare Systeme betrachteten strukturellen Eigenschaften umfassen einen erweiterten Stabilitätsbegriff sowie die Stabilitätsanalyse mittels der direkten Methode nach Ljapunow. Mit ausgewählten Verfahren zum Regler- und Beobachterentwurf für nichtlineare Systeme sowie einer kurzen Einführung in die robuste Regelung linearer Systeme mit Parameterunsicherheiten endet dieser Teil der Vorlesung. Im dritten Teil der Vorlesung Regelungstechnik II werden grundlegende Verfahren zum Entwurf optimaler Steuerungen und Regelungen für zeitdiskrete sowie zeitkontinuierliche dynamische Systeme vorgestellt. Im Mittelpunkt stehen dabei die diskrete dynamische Programmierung nach Bellman, die Hamilton-Jacobi-Bellman-Gleichung sowie das Maximumprinzip von Pontrjagin. Neben einer Einführung in das Themengebiet der dynamischen Optimierung stehen die für die praktische Anwendung wesentlichen Fragestellungen des Entwurfs zeitoptimaler Steuerungen sowie die Lösung so genannter LQR-Probleme (Entwurf von Regelungen mittels quadratischer Gütekriterien für lineare Systeme) im Mittelpunkt.
The cycle of violence as a function of PTSD and appetitive aggression: A longitudinal study with Burundian soldiers
Creators: name: Nandi, Corina
name: Crombach, Anselm
name: Elbert, Thomas
name: Bambonye, Manassé
name: Pryss, Rüdiger
name: Schobel, Johannes
name: Weierstall‐Pust, Roland
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: PTSD
subject: DDC 150 / Psychology
subject: Stress disorders, Post-traumatic
subject: Combat disorders; Therapy
subject: Military personnel
subject: Substance-related disorders
subject: Aggression
subject: Violence
subject: Posttraumatisches Stresssyndrom
subject: Soldat
subject: Afghanistan
subject: Irak

description: During deployment, soldiers face situations in which they are not only exposed to violence but also have to perpetrate it themselves. This study investigates the role of soldiers' levels of posttraumatic stress disorder (PTSD) symptoms and appetitive aggression, that is, a lust for violence, for their engaging in violence during deployment. Furthermore, factors during deployment influencing the level of PTSD symptoms and appetitive aggression after deployment were examined for a better comprehension of the maintenance of violence. Semi‐structured interviews were conducted with 468 Burundian soldiers before and after a 1‐year deployment to Somalia. To predict violent acts during deployment (perideployment) as well as appetitive aggression and PTSD symptom severity after deployment (postdeployment), structural equation modeling was utilized. Results showed that the number of violent acts perideployment was predicted by the level of appetitive aggression and by the severity of PTSD hyperarousal symptoms predeployment. In addition to its association with the predeployment level, appetitive aggression postdeployment was predicted by violent acts and trauma exposure perideployment as well as positively associated with unit support. PTSD symptom severity postdeployment was predicted by the severity of PTSD avoidance symptoms predeployment and trauma exposure perideployment, and negatively associated with unit support. This prospective study reveals the importance of appetitive aggression and PTSD hyperarousal symptoms for the engagement in violent acts during deployment, while simultaneously demonstrating how these phenomena may develop in mutually reinforcing cycles in a war setting.
Flexible radar front end with multimodal transition at 300 GHz
Creators: name: Geiger, Martin
name: Gut, Simon
name: Hügler, Philipp
name: Waldschmidt, Christian
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Dielectric waveguide
subject: Flexible radar sensor
subject: Integrated lens antenna
subject: Multimode interference
subject: MM-wave radar
subject: DDC 530 / Physics
subject: DDC 620 / Engineering & allied operations
subject: Lens antennas
subject: Radar Antennas
subject: Hohlleiter
subject: Radarsensor
subject: Linsenantenne

description: Especially for short-range radar sensors, a protection of the electronics against environmental damage like heat or humidity as well as a robust antenna front end are essential. In order to separate the sensitive electronics and the robust antenna spatially, a system concept for a 300-GHz radar with mechanically ﬂexible front end is presented in this paper. The ﬂexible front end is realized with a low-loss dielectric waveguide (DWG) with losses of around 15 dB/m. It is bendable up to a radius of 1 cm. An elliptical lens (30.9 dBi) at the end is used to focus the beam. The front end is fed by a radar MMIC in a QFN-like package with an integrated silicon lens. The wide beam is focused by simply placing a multimodal DWG above package and lens. The intentionally caused interference of the individual modes then results in a ﬁeld maximum in the center, and the fundamental mode can be fed into the DWG.
Examining the knowledge base and level of confidence of early childhood educators in physical literacy and its application to practice
Creators: name: Buckler, E. Jean
name: Bredin, Shannon S. D.
Publisher: name: The University of British Columbia
Year: 2024

description: Early childhood is an opportune time to develop physical literacy, acquire movement skills, and promote physical activity. Little is known about early childhood educators’ competence and confidence in physical literacy knowledge and its application to practice. The purpose of this research was to examine the competence and confidence of early childhood educators in physical literacy, and to determine whether exposure to information in this area influences their confidence level. A total of 85 participants completed an online survey. Physical activity knowledge was high; however, error detection and correction knowledge was lower, with high variability in responses. Mean confidence rating (out of 10) was lowest for locomotor skill error detection and correction (6.4±1.8) and highest for physical activity promotion (7.7±1.6). Confidence in movement skill development decreased significantly pre- to post-survey (p<0.001); highlighting a potential “topic exposure” effect. These findings demonstrate the need for physical literacy training for early childhood educators
The fate of nitrification and urease inhibitors in simulated bank filtration
Creators: name: Förster, Christina
name: Klitzke, Sondra
name: Scheurer, Marco
name: Ruhl, Aki Sebastian
name: Zeeshan, Muhammad
Publisher: name: My University
Year: 2023
Subjects: Uferfiltration
Oberflächengewässer
Nitrifikationshemmer
Biologischer Abbau

description: The application of nitrification and urease inhibitors (NUI) in conjunction with nitrogen (N) fertilizers improves the efficiency of N fertilizers. However, NUI are frequently found in surface waters through leaching or surface runoff. Bank filtration (BF) is considered as a low-cost water treatment system providing high quality water by efficiently removing large amounts of organic micropollutants from surface water. The fate of NUI in managed aquifer recharge systems such as BF is poorly known. The aim of this work was to investigate sorption and degradation of NUI in simulated BF under near-natural conditions. Besides, the effect of NUI on the microbial biomass of slowly growing microorganisms and the role of microbial biomass on NUI removal was investigated. Duplicate sand columns (length 1.7 m) fed with surface water were spiked with a pulse consisting of four nitrification (1,2,4-triazole, dicyanodiamide, 3,4-dimethylpyrazole and 3-methylpyrazole) and two urease inhibitors (n-butyl-thiophosphoric acid triamide and n-(2-nitrophenyl) phosphoric triamide). The average spiking concentration of each NUI was 5 ÎÌg/L. Experimental and modeled breakthrough curves of NUI indicated no retardation for any of the inhibitors. Therefore, biodegradation was identified as the main elimination pathway for all substances and was highest in zones of high microbial biomass. Removal of 1,2,4-triazole was 50% and n-butyl-thiophosphoric acid triamide proved to be highly degradable and was completely removed after a hydraulic retention time (HRT) of 24 h. 50% of the mass recovery for nitrification inhibitors except for 3,4-dimethylpyrazole was observed at the effluent (4 days HRT). In addition, a mild effect of NUI on microbial biomass was noted. This study highlights that the degradation of NUI in BF depends on HRT and microbial biomass. © 2023 Elsevier
A novel, highly sensitive and specific biomarker for Niemann-Pick type C1 disease
Creators: name: Giese, Anne-Katrin
name: Mascher, Hermann
name: Grittner, Ulrike
name: Eichler, Sabrina
name: Kramp, Guido
name: Lukas, Jan
name: Vruchte, Danielle Te
name: Eisa, Nada Al
name: Cortina-Borja, Mario
name: Porter, Forbes D.
name: Platt, Frances M.
name: Rolfs, Arndt
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: Niemann-Pick type C1 disease
subject: NPC1
subject: Biomarker
subject: HPLC-MS/MS
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Lysosomal storage disorders (LSDs), are a heterogeneous group of rare disorders caused by defects in genes encoding for proteins involved in the lysosomal degradation of macromolecules. They occur at a frequency of about 1 in 5,000 live births, though recent neonatal screening suggests a higher incidence. New treatment options for LSDs demand a rapid, early diagnosis of LSDs if maximal clinical benefit is to be achieved. Methods Here, we describe a novel, highly specific and sensitive biomarker for Niemann-Pick Type C disease type 1 (NPC1), lyso-sphingomyelin-509. We cross-validate this biomarker with cholestane-3β,5α,6β-triol and relative lysosomal volume. The primary cohort for establishment of the biomarker contained 135 NPC1 patients, 66 NPC1 carriers, 241 patients with other LSDs and 46 healthy controls. Results With a sensitivity of 100.0% and specificity of 91.0% a cut-off of 1.4 ng/ml was established. Comparison with cholestane-3β,5α,6β-triol and relative acidic compartment volume measurements were carried out with a subset of 125 subjects. Both cholestane-3β,5α,6β-triol and lyso-Sphingomyelin-509 were sufficient in establishing the diagnosis of NPC1 and correlated with disease severity. Conclusion In summary, we have established a new biomarker for the diagnosis of NPC1, and further studies will be conducted to assess correlation to disease progress and monitoring treatment.
Supplementary document for Nanostructured optical waveguide with a highly confined mode - 4695232.pdf
Creators: name: Chubchev, Eugene
name: Nechepurenko, Igor
name: Dorofeenko, A
name: Vinogradov, Alexey
name: Lisyansky, Alexander
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: In this Supplemental Document, the full set of the equations for the field components in the core, cladding, and outer medium is provided.
Study of Interlayer Adhesion and Development of Reinforcing Methods for 3D Concrete Printing
Creators: name: Marchment, Taylor Anthony
Publisher: name: Swinburne
Year: 2024

description: 3D Concrete Printing (3DcP) is a revolutionary automated construction technology that enables the building of complex geometries without moulds or supports at a reduced cost in a shorter timeframe. Printing involves the continuous extrusion of a stiff concrete mix out of a digitally controlled nozzle layer by layer. The two primary challenges that compromise the printed objects strength and hinders commercial adoption are (1) weak interlayer adhesion. (2) lack of integrated `in-process' interlayer reinforcement. This doctoral research identifies the factors affecting interlayer adhesion and develops methods of strengthening and reinforcing it as an `in-process' solution for large-scale 3DcP.
Vibration of laminated orthotropic composite plates and shells.
Creators: name: Li, Nong.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Engineering, Mechanical.

description: Almost all of the analytical solution techniques presented for composite plates and shells deal with either simply supported conditions or boundary conditions with at least a pair of opposite edges simply supported. In the present study, an alternative general approach, combining superposition and state space techniques is developed for the free vibration analysis of laminated orthotropic composite plates and shells having arbitrary boundary conditions. This study concentrates on the antisymmetric angle-ply laminated plates and cross-ply laminated plates and shells. Three commonly adopted theories, i.e., classical theory, first-order shear deformation theory and third-order shear deformation theory, have been employed and compared with one another to investigate the influence of transverse shear deformation, structural aspect ratio, length-to-thickness ratio, degree of anisotropy and the number of layers on natural frequency. Convergence tests have been carried out to guarantee the accuracy of the closed-form solutions. Wherever possible, numerical results generated by the present approach are compared with those reported in the published references. Accurate non-dimensional fundamental frequencies are presented for laminated plates and shells with two adjacent edges, three edges and four edges clamped and other edges simply supported. Such analyses have not been reported in the literature previously. Also, vibration analysis of a cantilever angle-ply antisymmetric plate with a point support is conducted to demonstrate the applicability of the present technique. It has been shown that the method works extremely well and excellent agreements are found between the present results and those generated by previous researchers. It has also been shown that more complicated boundary-value problems can be solved by this technique without any difficulty.
Simultaneous Precision Gravimetry and Magnetic Gradiometry with a Bose-Einstein Condensate: A High Precision, Quantum Sensor
Creators: name: Hardman, K. S.
name: Robins, N. P.
name: Everitt, P. J.
name: McDonald, G. D.
name: Manju, P.
name: Wigley, P. B.
name: Sooriyabandara, M. A.
name: Noschang Kuhn, Carlos
name: Debs, J. E.
name: Close, J. D.
Publisher: name: Swinburne
Year: 2024

description: A Bose-Einstein condensate is used as an atomic source for a high precision sensor. A 5×106  atom F=1 spinor condensate of 87Rb is released into free fall for up to 750 ms and probed with a T=130  ms Mach-Zehnder atom interferometer based on Bragg transitions. The Bragg interferometer simultaneously addresses the three magnetic states |mf=1,0,−1⟩, facilitating a simultaneous measurement of the acceleration due to gravity with a 1000 run precision of Δg/g=1.45×10−9 and the magnetic field gradient to a precision of 120  pT/m.
Supplementary Material: Exposition of Research, The Death Dinner and Performance Project: A Study of the Efficacy of Performance to Enhance Conversations Around Death and Dying
Creators: name: McCormick, Sheila
Publisher: name: University of Salford
Year: 2019
Subjects: classificationCode: 360403
subject: Drama, theatre and performance studies

description:
This Supplementary Material: Exposition of Research document Introduces the PaR project (The Death Dinner and Performance Project: A Study of the Efficacy of Performance to Enhance Conversations Around Death and Dying) providing an overview of the origins of the research. As well as outlining the objectives of the project, it provides a performance review and the critical context that surrounded the research.
It discusses in detail the research strategy for the Death Dinner and Performance project and outlines the outcomes of the project, what was learned and what future the project might have going forward.
Discrepancy between simulated and observed ethane and propane levels explained by underestimated fossil emissions
Creators: name: Dalsøren, Stig B.
name: Myhre, Gunnar
name: Hodnebrog, Øivind
name: Wallasch, Markus
Publisher: name: My University
Year: 2018

description: Ethane and propane are the most abundant non-methane hydrocarbons in the atmosphere. However, their emissions, atmospheric distribution, and trends in their atmospheric concentrations are insufficiently understood. Atmospheric model simulations using standard community emission inventories do not reproduce available measurements in the Northern Hemisphere. Here, we show that observations of pre-industrial and present-day ethane and propane can be reproduced in simulations with a detailed atmospheric chemistry transport model, provided that natural geologic emissions are taken into account and anthropogenic fossil fuel emissions are assumed to be two to three times higher than is indicated in current inventories. Accounting for these enhanced ethane and propane emissions results in simulated surface ozone concentrations that are 5-13% higher than previously assumed in some polluted regions in Asia. The improved correspondence with observed ethane and propane in model simulations with greater emissions suggests that the level of fossil (geologic + fossil fuel) methane emissions in current inventories may need re-evaluation. Quelle: https://www.nature.com
Locating the intense interstellar scattering towards the inner Galaxy
Creators: name: Dexter, J.
name: Deller, Adam
name: Bower, G. C.
name: Demorest, P.
name: Kramer, M.
name: Stappers, B. W.
name: Lyne, A. G.
name: Kerr, M.
name: Spitler, L. G.
name: Psaltis, D.
name: Johnson, M.
name: Narayan, R.
Publisher: name: Swinburne
Year: 2024

description: We use VLBA+VLA observations to measure the sizes of the scatter-broadened images of six of the most heavily scattered known pulsars: three within the Galactic Centre (GC) and three elsewhere in the inner Galactic plane (Delta l < 20 degrees). By combining the measured sizes with temporal pulse broadening data from the literature and using the thin-screen approximation, we locate the scattering medium along the line of sight to these six pulsars. At least two scattering screens are needed to explain the observations of the GC sample. We show that the screen inferred by previous observations of SGR J1745-2900 and Sgr A*, which must be located far from the GC, falls off in strength on scales less than or similar to 0 degrees.2. A second scattering component closer to (Delta < 2 kpc) or even (tentatively) within (Delta < 700 pc) the GC produces most or all of the temporal broadening observed in the other GC pulsars. Outside the GC, the scattering locations for all three pulsars are similar or equal to 2 kpc from Earth, consistent with the distance of the Carina-Sagittarius or Scutum spiral arm. For each object the 3D scattering origin coincides with a known H II region (and in one case also a supernova remnant), suggesting that such objects preferentially cause the intense interstellar scattering seen towards the Galactic plane. We show that the H II regions should contribute greater than or similar to 25 per cent of the total dispersion measure (DM) towards these pulsars, and calculate reduced DM distances. Those distances for other pulsars lying behind H II regions may be similarly overestimated.
Comparative Analysis of Sodium Hydroxide, Silane and Acetylation Treated Luffa Cylindrica Enforced Polylactic Acid Bio-Composites
Creators: name: Kamran, Muhammad Jahanzail
Publisher: name: Swinburne
Year: 2024

description: Various researchers have been concentrating on natural fibers and biodegradable polymers to fulfill the need of sustainable materials. The surface of Luffa Cylindrica (LC) was modified using sodium hydroxide, silane, and acetylation chemical surface treatments to enhance the compatibility of LC with Polylactic Acid. Mechanical testing, thermal analysis, FTIR, water uptake (%) and morphological analysis were performed on the chemically modified LC reinforced PLA bio-composite. Based on the experimental results, tensile, flexural strength and hardness was improved, water uptake (%) was reduced, and better thermal resistance was seen. Moreover, the morphological analysis (SEM) showed improved bonding between LC and PLA.
Combinatorial G-CSF/AMD3100 Treatment in Cardiac Repair after Myocardial Infarction
Creators: name: Rüder, Constantin
name: Haase, Tobias
name: Krost, Annalena
name: Langwieser, Nicole
name: Peter, Jan
name: Kamann, Stefanie
name: Zohlnhöfer, Dietlind
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2014
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Aims Several studies suggest that circulating bone marrow derived stem cells promote the regeneration of ischemic tissues. For hematopoietic stem cell transplantation combinatorial granulocyte-colony stimulating factor (G-CSF)/Plerixafor (AMD3100) administration was shown to enhance mobilization of bone marrow derived stem cells compared to G-CSF monotherapy. Here we tested the hypothesis whether combinatorial G-CSF/AMD3100 therapy has beneficial effects in cardiac recovery in a mouse model of myocardial infarction. Methods We analyzed the effect of single G-CSF (250 µg/kg/day) and combinatorial G-CSF/AMD3100 (100 µg/kg/day) treatment on cardiac morphology, vascularization, and hemodynamics 28 days after permanent ligation of the left anterior descending artery (LAD). G-CSF treatment started directly after induction of myocardial infarction (MI) for 3 consecutive days followed by a single AMD3100 application on day three after MI in the G-CSF/AMD3100 group. Cell mobilization was assessed by flow cytometry of blood samples drawn from tail vein on day 0, 7, and 14. Results Peripheral blood analysis 7 days after MI showed enhanced mobilization of white blood cells (WBC) and endothelial progenitor cells (EPC) upon G-CSF and combinatorial G-CSF/AMD3100 treatment. However, single or combinatorial treatment showed no improvement in survival, left ventricular function, and infarction size compared to the saline treated control group 28 days after MI. Furthermore, no differences in histology and vascularization of infarcted hearts could be observed. Conclusion Although the implemented treatment regimen caused no adverse effects, our data show that combinatorial G-CSF/AMD therapy does not promote myocardial regeneration after permanent LAD occlusion.
Supplementary document for A PSF degradation model of a polarization imaging system for wide-field subwavelength nanoparticles - 4696999.pdf
Creators: name: wu, qiong
name: Gao, Kun
name: Hua, Zizheng
name: Zhang, Zhenzhou
name: Zhao, Hanwen
name: Xiong, Jichuan
name: Yu, Peilin
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Discussion for different degradation
Antifouling biocides in German marinas - Exposure assessment and calculation of national consumption and emission
Creators: name: Daehne, Dagmar
name: Feibicke, Michael
name: Fürle, Constanze
name: Thomsen, Anja
Publisher: name: My University
Year: 2017

description: The authorization of biocidal antifouling products for leisure boats is subject of the EU Biocides Regulation 528/2012. National specifics may be regarded by the member states in their assessment of environmental risks. The aim of this survey was to collect corresponding data and to create a data base for the environmental risk assessment of antifouling active substances in German surface waters. Water concentrations of current antifouling active substances and selected break-down products were measured in a single-sampling campaign covering 50 marinas at inland and coastal areas. Increased levels were found for zinc, copper and cybutryne. For the latter, the maximum allowable concentration according to EU Directive 2013/39 was exceeded at 5 marinas. For copper, local environmental quality standards were exceeded at 10 marinas. Base data on the total boat inventory in Germany were lacking up to now. For that reason, a nationwide survey of mooring berths was conducted by use of aerial photos. About 206,000 mooring berths obviously used by boats with a potential antifouling application were counted. The blind spot of very small marinas was estimated at 20,000 berths. 71% of berths were located at freshwater sites illustrating the importance of navigable inland waterways for leisure boat activities and underline the need for a customized exposure assessment in these areas. Moreover, the national consumption of all antifouling products for leisure boats was calculated. The total amount of 794 t/a consisted of 179 t/a of inorganic copper compounds, 19 t/a of organic co-biocides and 49.5 t/a of zinc. With regard to weight proportion, 141 t/a Cu and 40 t/a Zn were consumed. Assuming an emission ratio of 50% during service life, 70.5 t/a of copper amounted to 15% of all external sources for copper release to German surface waters. These figures highlight the need of mitigation measures. This article is protected by copyright. All rights reserved © 1999 - 2017 John Wiley & Sons, Inc.
Development of novel techno-economic framework for enhancing a Tri-Ethylene Glycol-based natural gas dehydration unit
Creators: name: Kong, Zong Yang
Publisher: name: Swinburne
Year: 2024

description: The maximum purity of the regenerated Tri-Ethylene Glycol (TEG) in an absorption-based natural gas dehydration process is capped at 98.8% since the operating temperature of the reboiler cannot exceed 204 oC, otherwise the TEG will thermally degrade. Several enhanced dehydration processes are available to overcome this limitation such as the stripping gas dehydration process using a portion of dry product gas, inert gas, or volatile hydrocarbon (DRIZO process). This thesis presents a novel techno-economic framework for the selection of the best dehydration process that simultaneously meets the water dew point specification and generates the highest net profit margin.
The Terry Fox Research Institute Canadian Prostate Cancer Biomarker Network: an analysis of a pan-Canadian multi-center cohort for biomarker validation
Creators: name: Ouellet, Véronique
name: Aprikian, Armen
name: Bergeron, Alain
name: Brimo, Fadi
name: Bristow, Robert G.
name: Chevalier, Simone
name: Drachenberg, Darrel
name: Fazli, Ladan
name: Fleshner, Neil E.
name: Gleave, Martin E.
name: Karakiewicz, Pierre
name: Klotz, Laurence
name: Lacombe, Louis
name: Lattouf, Jean-Baptiste
name: Van Der Kwast, Theodorus
name: Squire, Jeremy A.
name: Latour, Mathieu
name: Trudel, Dominique
name: Mes-Masson, Anne-Marie
name: Saad, Fred
Publisher: name: BioMed Central
Year: 2018

description: Background: Refinement of parameters defining prostate cancer (PC) prognosis are urgently needed to identify patients with indolent versus aggressive disease. The Canadian Prostate Cancer Biomaker Network (CPCBN) consists of researchers from four Canadian provinces to create a validation cohort to address issues dealing with PC diagnosis and management. Methods: A total of 1512 radical prostatectomy (RP) specimens from five different biorepositories affiliated with teaching hospitals were selected to constitute the cohort. Tumoral and adjacent benign tissues were arrayed on tissue microarrays (TMAs). A patient clinical database was developed and includes data on diagnosis, treatment and clinical outcome. Results: Mean age at diagnosis of patients in the cohort was 61 years. Of these patients, 31% had a low grade (≤6) Gleason score (GS), 55% had GS 7 (40% of 3 + 4 and 15% of 4 + 3) and 14% had high GS (≥8) PC. The median follow-up of the cohort was 113 months. A total of 34% had a biochemical relapse, 4% developed bone metastasis and 3% of patients died from PC while 9% died of other causes. Pathological review of the TMAs confirmed the presence of tumor and benign tissue cores for > 94% of patients. Immunohistochemistry and FISH analyses, performed on a small set of specimens, showed high quality results and no biorepository-specific bias. Conclusions: The CPCBN RP cohort is representative of real world PC disease observed in the Canadian population. The frequency of biochemical relapse and bone metastasis as events allows for a precise assessment of the prognostic value of biomarkers. This resource is available, in a step-wise manner, for researchers who intend to validate prognostic biomarkers in PC. Combining multiple biomarkers with clinical and pathologic parameters that are predictive of outcome will aid in clinical decision-making for patients treated for PC.
title: The Randomized Controlled STRAWINSKI Trial
title: Procalcitonin-Guided Antibiotic Therapy after Stroke
titleType: Subtitle
Creators: name: Ulm, Lena
name: Hoffmann, Sarah
name: Nabavi, Darius
name: Hermans, Marcella
name: Mackert, Bruno-Marcel
name: Hamilton, Frank
name: Schmehl, Ingo
name: Meisel, Christian [U.V.M.]
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: stroke
subject: pneumonia
subject: antibiotic prophylaxis
subject: procalcitonin
subject: outcome
subject: infections
subject: biomarker-guided treatment
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background: Pneumonia is among the most common acute complications after stroke and is associated with poor long-term outcome. Biomarkers may help identifying stroke patients at high risk for developing stroke-associated pneumonia (SAP) and to guide early treatment. Aims: This trial investigated whether procalcitonin (PCT) ultrasensitive (PCTus)-guided antibiotic treatment of SAP can improve functional outcome after stroke. Methods: In this international, multicenter, randomized, controlled clinical trial with blinded assessment of outcomes, patients with severe ischemic stroke in the middle cerebral artery territory were randomly assigned within 40 h after symptom onset to PCTus-based antibiotic therapy guidance in addition to stroke unit care or standard stroke unit care alone. The primary endpoint was functional outcome at 3 months, defined according to the modified Rankin Scale (mRS) and dichotomized as acceptable (≤4) or unacceptable (≥5). Secondary endpoints included usage of antibiotics, infection rates, days of fever, and mortality. The trial was registered with http://ClinicalTrials.gov (Identifier NCT01264549). Results: In the intention-to-treat-analysis based on 227 patients (112 in PCT and 115 in control group), 197 patients completed the 3-month follow-up. Adherence to PCT guidance was 65%. PCT-guided therapy did not improve functional outcome as measured by mRS (odds ratio 0.79; 95% confidence interval 0.45–1.35, p = 0.47). Pneumonia rate and mortality were similar in both groups. Days with fever tended to be lower (p = 0.055), whereas total number of days treated with antibiotics were higher (p = 0.004) in PCT compared to control group. A post hoc analysis including all PCT values in the intention-to-treat population demonstrated a significant increase on the first day of infection in patients with pneumonia and sepsis compared to patients with urinary tract infections or without infections (p < 0.0001). Conclusion: PCTus-guided antibiotic therapy did not improve functional outcome at 3 months after severe ischemic stroke. PCT is a promising biomarker for early detection of pneumonia and sepsis in acute stroke patients.
WAYS OF IMPLEMENTING NEW TECHNOLOGIES IN INNOVATION MANAGEMENT
Creators: name: Mustafoyev, Asadbek
Publisher: name: Zenodo
Year: 2024

description: This article analyzes the ways of innovative management to introduce new technologies and their impact on enterprise efficiency. The importance of introducing new technologies, the main principles and strategies of innovation management are considered. It also discusses the importance of technology research, adaptation, and employee training processes, as well as ways to automate processes and create new products. The results of the article show the positive impact of the introduction of new technologies on the overall efficiency, competitiveness and financial results of the enterprise.
Supplementary document for A PSF degradation model of a polarization imaging system for wide-field subwavelength nanoparticles - 4696999.pdf
Creators: name: wu, qiong
name: Gao, Kun
name: Hua, Zizheng
name: Zhang, Zhenzhou
name: Zhao, Hanwen
name: Xiong, Jichuan
name: Yu, Peilin
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Discussion for different degradation
Mechanisms underlying emotion processing in the broader autistic phenotype
Creators: name: Mu, Eveline
Publisher: name: Swinburne
Year: 2024

description: This thesis examined the role of early visual pathways in communicating facial emotional information, and whether this interacts in neurotypicals with varying autistic tendencies. It was found that neurotypicals with high levels of autistic traits share similar behavioural and electrophysical characteristics as individuals with clinical autism spectrum disorder. The findings provide insight into processing differences that contribute to the autism phenotype, and highlights that the weighting of inputs to cortex through the pulvinar and lateral geniculate nucleus may differ for those with low and high autistic traits.