cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Renewal of intestinal stem cells lacking intrinsic survival program requires microbiome and immune signaling input
Creators: name: Zhang, Xiao
Publisher: name: No Publisher Supplied
Year: 2020

description: Being one important part of the digestive system, the intestine is responsible for nutrient uptake and for establishing a critical barrier against luminal insults from harsh chemicals or pathogens. Both functions are vital for the survival of the host. Strictly defined architecture of intestinal epithelial cells and the gradient of signaling cues along the villus-crypt axis ensure the maintenance of adult intestinal stem cells, as well as proper regeneration and differentiation of all intestinal epithelial cell types. The Rho family small GTPase Cdc42 controls the proper division of intestinal stem cells and affects subsequent fate-determination of the progenitor cells. How the intestinal epithelium maintains homeostasis and regenerative capacity during constant exposure to genotoxic and pathogenic insults is unclear. We found that ex vivo survival and clonogenicity of intestinal stem cells (ISCs)strictly required Cdc42-mediated response, and Cdc42-deficient enteroids underwent rapid apoptosis. Mechanistically, Cdc42 engaged EGFR and enabled MAPK signaling. Accordingly, mice engineered to have boosted Cdc42-MAPK signaling in ISCs showed enhanced regeneration and were protected from epithelial injury. However, mice with Cdc42-deficient epithelium were viable and maintained functional homeostasis. An ex vivo screen uncovered that a number of inflammatory cytokines restored growth of Cdc42-deficient enteroids. Indeed, intestinal regeneration in mice lacking epithelial Cdc42 was compromised when cytokine-signaling or microbiota sensing was abolished. Antibiotic treatment, IL-22 deficiency, or Stat3 blockage compromised epithelial survival and injury-induced regeneration in mice lacking epithelial Cdc42. Data from this thesis shed lights on how ISC-intrinsic survival programs collaborate with signals from immune and microbiome compartments to provide non-redundant layers of protection for epithelial integrity. We conclude that signaling inputs from microbiome and lamina propria lymphocytes facilitate survival of ISCs with defective survival program. These results suggest that activation of specific epithelial extrinsic signals may benefit intestinal mucosal regeneration in hosts with diminished survival program such as during severe genotoxic or pathogenic injuries.
Intro to Open Science
Creators: name: Guzman-Ramirez, Liz
Publisher: name: Forschungzentrum Jülich
Year: 2022
Subjects: open science, open research, open and responsible science
http://id.loc.gov/authorities/subjects/sh2022002066
http://id.loc.gov/authorities/subjects/sh2005002533

description: Lecture at Seminar (), ; doi:10.5281/ZENODO.7128578
description: Introduction to Open Science for bachelor students. The lecture includes a brief description of Open Science, the most common practices for research and an assignment to experience the 'paywall' on Open Access.
Managing innovation: a typology of theories and some practical implications for New Zealand firms
Creators: name: De Waal, Anton
name: Maritz, Alex
name: Prebble, Dean
Publisher: name: Swinburne
Year: 2024

description: The quality of a firm's innovations is determined by a variety of factors. One such factor is the performance of the firm's innovation system. This in turn is partially determined by how well the innovation system is managed. Despite plenty of scholarly activity in this field of study, a comprehensive, generic framework for managing innovation is still lacking. Combining oldfashioned management theory with modern-day innovation concepts, a new conceptual framework for the management of innovation is put forward in this paper. Its scope of application is much broader than that of contemporary theory in the sense that it addresses not only aspects of the innovation process, but also strategy, metrics, supportive organization, leadership, and innovation tools. In the first of a series of papers the current paper, through exploratory quantitative research, sheds light on how well New Zealand managers/CEOs are managing innovation within their firms. The results indicate that while there are many encouraging signs, there is also ample scope for improvement. New Zealand firms lack strong leadership in creating 'innovation friendly' cultures and seem reluctant to define appropriate innovation metrics and regularly assess their organizational innovation performances.
Adaptive responses to ionizing radiation in normal human skin fibroblasts.
Creators: name: Azzam, Edouard Alexandre.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Biology, Molecular.

description: Plateau-phase normal human skin fibroblasts (AG1522) pre-exposed to low-dose-rate ionizing radiation (IR) became less susceptible to the lethal effect of a subsequent acute challenge dose of radiation. A threshold and an optimum adapting dose were observed. This adaptive response (AR) at the survival level was accompanied by a decreased number of chromosomal breaks due to the challenge dose, as indicated by a reduction in the frequency of micronucleus formation. The frequency of micronucleus formation was further reduced when an incubation period at 37$\sp\circ$C separated the challenge dose and the adapting dose delivered at either low- or high-dose-rate. The rate of reduction of micronucleus formation was higher for the low dose-rate as compared to the high dose-rate adapting dose, suggesting that the ability of human cells to adapt to radiation increases with decreasing rates of damage. A certain amount of damage per unit time with which the cell can cope appears to be necessary to trigger the AR to IR. The rate of repair of DNA double-strand breaks, as indicated by the frequency of micronucleus formation, was higher in adapted cells, suggesting that the mechanism of adaptation could include increased repair capacity and/or an increased ease of access of repair enzymes to the lesion. Adapted cells also showed a much longer delay in reaching the binucleate state than non-adapted cells, suggesting a second mechanism of adaptation which may increase the time available for DNA repair. The analysis of RNA from adapted cells showed a decreased level of cyclin A and cyclin B transcripts consistent with a mechanism leading to a delay in the progression of the cells in the cell cycle. The transcript levels of other genes possibly involved in the cellular response to IR were also altered. Rodent C3H 10T${1\over2}$ cells showed a similar adaptation when assayed for micronucleus formation. The adapted cells were also protected against transformation to malignancy by a subsequent high dose of radiation. Transformation frequency was reduced about two-fold by low-dose-rate adapting doses ranging from 0.1 to 1.5 Gy. Flow cytometric measurements showed that the cell cycle distribution of the plateau phase cells used was unaltered during the various treatments, indicating that the observed AR cannot be attributed to selection of cells at a radioresistant stage of the cell cycle.
Astronomy and Open Science
Creators: name: Cruz, Maria J.
Publisher: name: Forschungzentrum Jülich
Year: 2019
Subjects: astronomy
open science
FAIR
open data
citizen science
open source software
open research
reproducibility

description: Lecture at Seminar (), ; doi:10.5281/ZENODO.2625108
description: Materials used during an Open Science Masterclass for 2nd-year physics and astronomy bachelor students at Leiden University on 4 April 2019. The Masterclass was part of the Modern Astronomical Research bachelor course. The materials include the full presentation, which consisted of three parts: About my career as someone who studied astronomy and moved on to do other things, to give an idea of what are the skills an astronomer could use in different contexts About astronomy as an example for Open Science Reproducible Lego Workshop to highlight the importance of metadata, documentation, and community standards The two last part are also made available as separate presentations. The results of a Mentimeter survey of the students are also included.
Keeping up with the times: how national public health and governmental organizations communicate about cannabis on Twitter
Creators: name: Van Draanen, Jenna
name: Krishna, Tanvi
name: Tsang, Christie
name: Liu, Sam
Publisher: name: BioMed Central
Year: 2019

description: Background: Public health and governmental organizations are expected to provide guidance to the public on emerging health issues in accessible formats. It is, therefore, important to examine how such organizations are discussing cannabis online and the information that is being provided to the public about this increasingly legal and available substance. Methods: This paper presents a concise thematic analysis of both the volume and content of cannabis-related health information from selected (n = 13) national-level public health and governmental organizations in Canada and the U.S. on Twitter. Results: There were eight themes identified in Tweets including 1) health-related topics; 2) legalization and legislation; 3) research on cannabis; 4) special populations; 5) driving and cannabis; 6) population issues; 7) medical cannabis, and 8) public health issues. The majority of cannabis-related Tweets from the organizations studied came from relatively few organizations and there were substantial differences between the topics covered by U.S. and Canadian organizations. The organizations studied provided limited information regarding how to use cannabis in ways that will minimize health-related harms. Conclusions: Authoritative organizations that deal with public health may consider designing timely social media communications with emerging cannabis-related information, to benefit a general public otherwise exposed to primarily pro-cannabis content on Twitter.
title: Research in Urbanism Series, Vol. 5 (2019): Housing and Urban Regeneration of Deprived Neighborhoods in Santiago
title: Housing and Urban Regeneration of Deprived Neighborhoods in Santiago
titleType: AlternativeTitle
Creators: name: Research In Urbanism Series
Publisher: name: Research in Urbanism Series
Year: 2019

description: This publication is a joint project between the Department of Management in the Built Environment at Delft University of Technology, and the School of Architecture at Pontificia Universidad Católica de Chile, which seeks to reflect on alternative housing production models that have arisen in response to social, economic and political changes in both contexts. Although the experiences have followed different paths and therefore, have had different results, they share a common goal: the search for alternative housing models that are collaborative, affordable and have the potential for regenerating urban neighborhoods. The first milestone of the cooperation between both institutions was an academic experience in a workshop format carried out at Santiago in November 2017. The workshop titled: “Imagining housing renewal in deprived areas” became an opportunity to discuss among scholars, students, civil society organizations, and the community. As a result of this debate, a number of topics and questions were identified, which form the basis of the conceptual framework of this publication. Through a compendium of short articles, this book presents an academic debate regarding collaborative housing processes in urban regeneration, stemming both from local experiences and from the identification of north-south and south-north perspectives. BOOK DATA Publisher TU Delft Open // Editors Luz María Vergara, Cristián Robertson, Darinka Czischke, Elke Schlack, Rodrigo Tapia // Publication date November 2019 // Pages 176 // Full color// ISBN 978-94-6366-222-2
description: Collaborative Housing...39-52 Public and collective space in ‘9x18 settlements’...155-164 Collective Housing in Chile...53-70 Conclusions...165-172 Informal Collaborative Housing...71-80 International Workshop...83-114 Challenges of Densification in 9x18 Neighbourhoods...117-124 Introduction...8-14 Extended-Household as a Co-Residence Strategy...125-134 Collaborative Housing Processes...17-26 (Self) Housing Management...135-144 Reflections on the European Social Housing Model and Opportunities for Collaborative Housing from a Dutch Perspective...27-38 Mobility and Micro Accessibility, the Challenges of Public Space...145-154
The EoR sensitivity of the Murchison Widefield Array
Creators: name: Beardsley, A. P.
name: Hazelton, B. J.
name: Morales, M. F.
name: Arcus, W.
name: Barnes, D.
name: Bernardi, G.
name: Bowman, J. D.
name: Briggs, F. H.
name: Bunton, J. D.
name: Cappallo, R. J.
name: Corey, B. E.
name: Deshpande, A.
name: deSouza, L.
name: Emrich, D.
name: Gaensler, B. M.
name: Goeke, R.
name: Greenhill, L. J.
name: Herne, D.
name: Hewitt, J. N.
name: Johnston-Hollitt, M.
name: Dobie, Dougal
name: Kasper, J. C.
name: Kincaid, B. B.
name: Koenig, R.
name: Kratzenberg, E.
name: Lonsdale, C. J.
name: Lynch, M. J.
name: McWhirter, S. R.
name: Mitchell, D. A.
name: Morgan, E.
name: Oberoi, D.
name: Ord, S. M.
name: Pathikulangara, J.
name: Prabu, T.
name: Remillard, R. A.
name: Rogers, A. E. E.
name: Roshi, A.
name: Salah, J. E.
name: Sault, R. J.
name: Udaya Shankar, N.
name: Srivani, K. S.
name: Stevens, J.
name: Subrahmanyan, R.
name: Tingay, S. J.
name: Wayth, R. B.
name: Waterson, M.
name: Webster, R. L.
name: Whitney, A. R.
name: Williams, Andrew
name: Williams, C. L.
name: Wyithe, J. S. B.
Publisher: name: Swinburne
Year: 2024

description: Using the final 128 antenna locations of the MurchisonWidefield Array (MWA), we calculate its sensitivity to the epoch of reionization (EoR) power spectrum of redshifted 21 cm emission for a fiducial model and provide the tools to calculate the sensitivity for any model. Our calculation takes into account synthesis rotation, chromatic and asymmetrical baseline effects, and excludes modes that will be contaminated by foreground subtraction. For the fiducial model, the MWA will be capable of a 14σ detection of the EoR signal with one full season of observation on two fields (900 and 700 h).
Performance evaluation of a computer simulation of an artificial arm using the principle of extended physiological proprioception.
Creators: name: Philippe-Auguste, Sébastien.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Engineering, Biomedical.

description: This research work investigates a control strategy for artificial arms called Extended Physiological Proprioception (EPP). EPP control relies on the fact that the body's natural position feedback, also called proprioception, can be "extended" outside the body to a tool or, in this case, an artificial arm. Hence, providing closed-loop operation without the use of visual feedback. The presence of a natural source of feedback is essential if subconscious operation of an artificial arm is desired. A hardware artificial arm was not used in this research, instead, a software simulation based on a sample mathematical model was employed. The interface between the human operation and the artificial arm was a virtual reality. The immense exploratory potential of virtual reality combined with our simulation was used to: (1) prove that EPP is adequate control strategy to "communicate the intent" of the operator to the artificial arm; (2) show that subconscious operation of the arm was possible, (3) demonstrate that several motions (realized through programmed linkages) could be learned, used and remembered, (4) show that adequate discrimination between the various linkages (motions) could be easily done; and finally (5) allow the formulation of various recommendations for future design of EPP controlled artificial arms.
Back into life: transdisciplinary trauma research
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Traumaforschung
subject: DDC 610 / Medicine & health
subject: Traumatology
subject: Wounds and injuries
subject: Trauma
subject: Traumatologie
subject: Universität Ulm

description: In Ulm, we deal with all aspects of the theme "trauma" at an advanced scientific level. The facilities in the University and the surrounding region examine all facets of trauma. This ranges from physical trauma caused by external force, which may result from traffic or sports accidents, or accidents at work, to psychological trauma triggered by mental injuries. There is a close relationship between physical and mental injuries. Our objective in Ulm is to improve our understanding of the complex mechanisms of damage and cure, to develop new therapies and to reduce long-term damage. Our physicians and scientists enjoy an international reputation. As their areas of expertise are complementary, they can interweave basic, translational and clinical research on trauma in a unique manner.
Supplementary document for Controllable double-helical microstructures by photonic orbital angular momentum for chiroptical response - 5098682.pdf
Creators: name: Ni, Jincheng
name: Hu, Yanlei
name: Liu, Shunli
name: Lao, Zhaoxin
name: Ji, Shengyun
name: Pan, Deng
name: Zhang, Chenchu
name: Xu, Bing
name: Li, Jiawen
name: Wu, Dong
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Supplemental material_R1.pdf
Creators: name: Libardi, Cleiton
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 420702
subject: Exercise physiology

description: We explored, for the first time, the influence of AR through the separation of cytoplasmic and nuclear cell fractions (i.e., cAR, nAR and AR-DNA) on muscle hypertrophy responsiveness to resistance training. The absence of muscle hypertrophy in naïve individuals does not seem to be explained by baseline values, and acute or chronic changes in AR markers.
Open Science e comunicazione
Creators: name: Giglia, Elena
Publisher: name: Forschungzentrum Jülich
Year: 2020
Subjects: Open Science, Open Access, FAIR data, Data Management Plans

description: Lecture at Seminar (), ; doi:10.5281/ZENODO.3607695
description: Seminar held on Nov. 22, 2019 (prof. Paccagnella course) Topics: crisis of the current scholarly communication system, the Open alternative, European policies and framework, Open Access in practice, FAIR and Open data, Data Management Plans
title: Research in Urbanism Series, Vol. 4 (2016): Geo-Design: Advances in bridging geo-information technology, urban planning and landscape architecture
title: Geo-Design: Advances in bridging geo-information technology, urban planning and landscape architecture
titleType: AlternativeTitle
Creators: name: Research In Urbanism Series
Publisher: name: Research in Urbanism Series
Year: 2016

description: Geo-Design. Advances in bridging geo-information technology and design bring together a wide variety of contributions from authors with backgrounds in urban planning, landscape architecture, education and geo-information technology presenting the latest insights and applications of geo-design. Geo-Design is here understood as a hybridization of the concepts "Geo" – representing the modeling, analytical and visualization capacities of GIS, and "Design" – representing spatial planning and design, turning existing situations into preferred ones. Through focusing on interdisciplinary design-related concepts and applications of GIS international experts share their recent findings and provide clues for the further development of geo-design. This is important since there is still much to do. Not only in the development of geo-information technology, but especially in bridging the gap with the design-disciplines. The uptake on using GIS is still remarkably slow among landscape architects, urban designers and planners, and when utilized it is often restricted to the basic tasks of mapmaking and data access. Knowledge development and dissemination of applications of geodesign through research, publications, and education, therefore, remain key factors. This publication draws upon the insights shared at the Geodesign Summit Europe held at Delft University of Technology in 2014. All contributions in the book are double-blind reviewed by experts in the field. BOOK DATA Publisher TU Delft Open // Editors Steffen Nijhuis, Sisi Zlatanova, Eduardo Dias, Frank van der Hoeven, Stefan van der Spek // Publication date December 2016 // Pages 284 // Full colour // ISBN 978-9492516428
description: Geo-Design...7-8 Applications of GIS in landscape design research...43-56 Bringing Geodesign to the world in a massive, open, online engagement...207-228 Beginnings of Geodesign...9-24 Using satellite imagery analysis to classify and redesign provincial parks for a better cooling effect on cities...157-184 Spatial tools for diagnosing the degree of safety and liveability, and to regenerate urban areas in the Netherlands...139-156 Integrating Virtual Reality, Motion Simulation and a 4D GIS...25-42 From Metaplanning to PSS 2.0...57-70 Integrating Geodesign and game experiments for negotiating urban development...70-92 Detecting spatial features from data-maps...93-110 Geodesign the multi-layered water safety...113-138 Combining GIS and BIM for facility reuse...185-204 Creating a Geodesign syllabus for landscape architecture in Denmark...229-246
Implications of the heat generation of LMR-NCM on the thermal Behavior of large-format lithium-ion batteries
Creators: name: Kraft, Ludwig
name: Hoefling, Alexander
name: Zünd, Tanja
name: Kunz, Alexander
name: Steinhardt, Marco
name: Tübke, Jens
name: Jossen, Andreas
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Batteries–Li-ion
subject: LMR-NCM
subject: NCA
subject: Heat generation
subject: Thermal behavior
subject: Voltage hysteresis
subject: DDC 540 / Chemistry & allied sciences
subject: Lithium ion batteries
subject: Modeling
subject: Lithium-Ionen-Akkumulator

description: Lithium- and manganese-rich NCM (LMR-NCM) cathode active materials exhibit a pronounced energy inefficiency during charge and discharge that results in a strong heat generation during operation. The implications of such a heat generation are investigated for large-format lithium-ion batteries. Small laboratory cells are generally considered isothermal, but for larger cell formats this heat cannot be neglected. Therefore, the heat generation of LMR-NCM/graphite coin cells and NCA/graphite coin cells as a reference is measured for varying charge/discharge rates in an isothermal heat flow calorimeter and scaled to larger standardized cell formats. With the aid of thermal 3D models, the temperature evolution within these cell formats under different charge/discharge operations and cooling conditions is analyzed. Without an additional heat sink and any active cooling of larger LMR-NCM/graphite cells, discharge C-rates lower than C/2 are advisable to keep the cell temperature below a critical threshold. If the loads are increased, the cooling strategy has to be adapted to the specific cell format, otherwise critical temperatures above 60 °C are easily reached. For the investigated convective surface cooling and base plate cooling scenarios, thick prismatic cell formats with LMR-NCM are generally unfavorable, as the large amount of heat cannot be adequately dissipated.
Temps et enfermement : récits de femmes.
Creators: name: Mercenier, Frédérique.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Women's Studies.

description: L'objet de cette recherche consiste en un questionnement de la dimension temporelle de l'enfermement. Il s'articule autour de deux facettes du temps: la premiere, subjective, est centree sur le rapport au temps, sur la maniere dont il est vecu par des femmes incarcerees; la seconde, objective, s'interesse a sa regulation par l'institution carcerale. Le premier theme developpe questionne le rapport que les femmes incarcerees entretiennent avec le temps de leur sentence. Ce dernier est vecu comme un probleme existentiel, la survie necessitant une recherche de sens qui sera l'enjeu f'une dechirure identitaire. Le second theme examine la dialectique enter le temps institue et instituant ainsi que le rapport de soumission des femmes a cette structure spatio-temporelle rigide, enjeu eventuel d'une rupture identitaire. Le dernier theme consiste en la resultante des deux premiers par l'etude du positionnement dans le passe, le present et l'avenir ainsi que l'insecription du temps carceral dans la trajectoire de vie. (Abstract shortened by UMI.)
title: Research in Urbanism Series, Vol. 3 (2015): Flowscapes: Designing infrastructure as landscape
title: Flowscapes: Designing infrastructure as landscape
titleType: AlternativeTitle
Creators: name: Research In Urbanism Series
Publisher: name: Research in Urbanism Series
Year: 2015

description: Flowscapes explores infrastructure as a type of landscape and landscape as a type of infrastructure. The hybridization of the two concepts seeks to redefine infrastructure beyond its strictly utilitarian definition, while allowing spatial design to gain operative force in territorial transformation processes. The publication provides perspectives on the subject from design-related disciplines such as architecture, urban design, urban planning, landscape architecture and civil engineering. The book builds upon the multidisciplinary colloquium on landscape infrastructures, that is part of the Flowscapes graduation design studio of Landscape Architecture at the TU Delft. The authors explore concepts, methods and techniques for design-related research on landscape infrastructures. Their main objective is to engage environmental and societal issues by means of integrative and design oriented approaches. Through focusing on interdisciplinary design-related research of landscape infrastructures they provide important clues for the development of spatial armatures that can guide urban and rural development and have cultural and civic significance. The geographical context of the papers covers Europe, Africa, Asia and Northern America. All contributions in the book are double blind reviewed by experts in the field. BOOK DATA Publisher TU Delft // Editors Steffen Nijhuis, Daniel Jauslin, Frank van der Hoeven // Publication date April 2015 // Pages 324 // Full colour // ISBN 978-9461864727 // Price €37 / $40
description: Urban landscape infrastructures...13-34 Waking Leviathan...81-107 Design challenges of multifunctional flood defences...275-292 The diabolic highway...111-134 A critical approach to some new ideas about the Dutch flood risk system...293-322 A bridge with a view a view with a bridge...135-158 A road trip on European highways. Considering the spatial qualities of E75 and E50...159-177 City pig farm...181-204 Representing nature...205-228 Mapping flows...35-56 Infrastructure as landscape as architecture...229-251 Planning with water and traffic networks...57-80 The synergy between flood risk protection and spatial quality in coastal cities...255-274
Reproducibility And Open Science
Creators: name: Ainsworth, Rachael
Publisher: name: Forschungzentrum Jülich
Year: 2018
Subjects: Reproducibility
Open Science
Data Science

description: Lecture at Seminar (), ; doi:10.5281/ZENODO.1464853
description: Presentation slides in both .pptx and .pdf formats for an invited talk I gave at the Alan Turing Institute in the British Library as part of the Data Science for Experimental Design workshop on 17 October 2018. Abstract: Making research results more accessible and reproducible can contribute to better and more efficient science, however widespread adoption of open research practices has not yet been achieved. Funding agencies (such as the European Commission Horizon 2020) are increasingly requiring research products (such as data and publications) to be made openly available in order to make results more accessible, transparent and reproducible. Recent studies have also shown that open research practices are associated with benefits to the researcher such as increases in citations, media attention, potential collaborators, job and funding opportunities. In this talk I will discuss the different aspects of Open Science, the barriers we face to practicing openly, how to 'open' up your research workflow using open and transparent data and software services in order to reap the benefits associated with open research practices, and highlight current open projects in STEM.
Finding Hadamard and (epsilon,delta)-Quasi-Hadamard Matrices with Optimization Techniques
Creators: name: Buteau, Samuel
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Hadamard matrices
Optimization

description: Existence problems (proving that a set is nonempty) abound in mathematics, so we look for generally applicable solutions (such as optimization techniques). To test and improve these techniques, we apply them to the Hadamard Conjecture (proving that Hadamard matrices exist in dimensions divisible by 4), which is a good example to study since Hadamard matrices have interesting applications (communication theory, quantum information theory, experiment design, etc.), are challenging to find, are easily distinguished from other matrices, are known to exist for many dimensions, etc.. In this thesis we study optimization algorithms (Exhaustive search, Hill Climbing, Metropolis, Gradient methods, generalizations thereof, etc.), improve their performance (when using a Graphical Processing Unit), and use them to attempt to find Hadamard matrices (real, and complex). Finally, we give an algorithm to prove non-trivial lower bounds on the Hamming distance between any given matrix with elements in {+1,-1} and the set of Hadamard matrices, then we use this algorithm to study matrices with similar properties to Hadamard matrices, but which are far away (with respect to the Hamming distance) from them.
I diritti dell'uomo, la sovranità nazionale, la Carta europea dei diritti fondamentali e la Costituzione europea
Creators: name: Hofmann, Hasso
Publisher: name: Alma Mater Studiorum, University of Bologna
Year: 2010

description: I                                diritti dell'uomo, la sovranità nazionale, la Carta                                europea dei diritti fondamentali e la Costituzione                                europea
Viral Marketing: A New Branding Strategy to Influence Consumers
Creators: name: Yang, Xiaofang
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Viral Marketing
electronic Word-of-Mouth Communication (eWOM)
Internet Marketing
New Media

description: The rapid penetration of the Internet and the prevalence of various social media facilitated by new technologies provide new opportunities for how marketing techniques are developed and refined. The creation of viral marketing has been driven by technological innovations and cultural changes. Responding to marketing trends and catering to consumers’ psychological demands and behavioral changes, viral marketing represents the latest online customer-centric marketing (Shukla, 2010). Extending the advertising effects of word-of-mouth (WOM) communication and Internet marketing, viral marketing has demonstrated considerable success and utility in a promotional phase and development process of a product and/or service. This study intends to illustrate the benefits and challenges of viral marketing. The effects and concerns with the adoption of viral marketing are reinforced by previous research and findings from marketer and consumer focus groups. This thesis will contribute to building a theoretical and empirical foundation for viral marketing research and professional practice.
The VSOP 5 GHz Active Galactic Nucleus Survey. II. Data calibration and imaging
Creators: name: Lovell, James E.
name: Moellenbrock, G. A.
name: Horiuchi, Shinji
name: Fomalont, E. B.
name: Scott, W. K.
name: Hirabayashi, Hisashi
name: Dodson, R. G.
name: Dougherty, S. M.
name: Edwards, Philip G.
name: Frey, S.
name: Gurvits, L. I.
name: Lister, Matthew L.
name: Murphy, David W.
name: Paragi, Z.
name: Piner, B. Glenn
name: Shen, Z. Q.
name: Taylor, A. Russell
name: Tingay, Steven J.
name: Asaki, Yoshiharu
name: Moffett, D.
name: Murata, Yasuhiro
Publisher: name: Swinburne
Year: 2024

description: The VLBI Space Observatory Programme (VSOP) mission is a Japanese-led project to study radio sources with sub-milliarcsecond angular resolution using an orbiting 8 m telescope, HALCA, and global arrays of Earth-based telescopes. Approximately 25% of the observing time has been devoted to a survey of compact active galactic nuclei (AGNs) at 5 GHz that are stronger than 1 Jy—the VSOP AGN Survey. This paper, the second in a series, describes the data calibration, source detection, self-calibration, imaging, and modeling and gives examples illustrating the problems specific to space VLBI. The VSOP Survey Web site, which contains all results and calibrated data, is described.
Planar cavity modes in void channel polymer photonic crystals
Creators: name: Ventura, Michael J.
name: Straub, Martin
name: Gu, Min
Publisher: name: Swinburne
Year: 2024

description: Planar dielectric microcavities embedded in woodpile void channel photonic crystals with stop bands in the stacking direction ranging from 4.3 to 4.8 µm in wavelength were generated by femtosecond-laser direct writing in a solid polymer. Infrared transmission spectra revealed fundamental and second-order modes crossing the stop gap region with a free spectral range of 430 nm on varying the microcavity size from 0.3 to 2.25 µm. Supercell calculations confirmed the cavity size dependence of highly localized cavity modes, whereas the angle of incidence was accounted for using a simple Fabry-Perot model.
title: Research in Urbanism Series, Vol. 2 (2011): Exploring the Visual Landscape: Advances in physiognomic landscape research in the Netherlands
title: Exploring the Visual Landscape: Advances in physiognomic landscape research in the Netherlands
titleType: AlternativeTitle
Creators: name: Research In Urbanism Series
Publisher: name: Research in Urbanism Series
Year: 2011

description: Exploring the Visual Landscape is about the combination of landscape research and planning, visual perception and Geographic Information Science. It showcases possible ways of getting a grip on themes like: landscape openness, cluttering of the rural landscape, high-rise buildings in relation to cityscape, historic landscapes and motorway panoramas. It offers clues for visual landscape assessment of spaces in cities, parks and rural areas. In that respect, it extends the long tradition in the Netherlands on physiognomic landscape research and shows the state of the art at this moment. Exploring the Visual Landscape offers important clues for theory, methodology and application in research and development of landscapes all over the world, from a specifically Dutch academic context. It provides a wide range of insights into the psychological background of landscape perception, the technical considerations of geomatics and methodology in landscape architecture, urban planning and design. Furthermore, there are some experiences worthwhile considering, which demonstrate how this research can be applied in the practice of landscape policy making. BOOK DATA Publisher IOS Press // Editors Steffen Nijhuis, Ron van Lammeren, Frank van der Hoeven // Publication date September 2011 // Pages 336 // Duo-colour // ISBN 978-1607508328 // Price €80 / $116 Excl. VAT
description: Geomatics in physiognomic landscape research...73-97 Hi Rise, I can see you!...277-301 Visual research in landscape architecture...103-145 Visions of Belle van Zuylen...303-315 Mapping landscape attractiveness...147-161 The one- and two-dimensional isovists analyses in Space Syntax...163-183 Virtual historical landscapes...185-203 Exploring visual landscapes...15-39 Mapping landscape openness with isovists...205-223 Psychology of the visual landscape...41-54 Landscape policy and visual landscape assessment...229-259 The phenomenological experience of the visual landscape...57-71 Preserving panoramic views along motorways through policy...261-275
title: Research in Urbanism Series, Vol. 1 (2008): Urbanism on Track: Application of tracking technologies in urbanism
title: Urbanism on Track: Application of tracking technologies in urbanism
titleType: AlternativeTitle
Creators: name: Research In Urbanism Series
Publisher: name: Research in Urbanism Series
Year: 2008

description: Tracking technologies such as GPS, mobile phone tracking, video and RFID monitoring are rapidly becoming part of daily life. Technological progress offers huge possibilities for studying human activity patterns in time and space in new ways. Delft University of Technology (TU Delft) held an international expert meeting in early 2007 to investigate the current and future possibilities and limitations of the application of tracking technologies in urban design and spatial planning. This book is the result of that expert meeting. Urbanism on Track introduces the reader to the basics of tracking research and provides insight into its advantages above other research techniques. But it also shows the bottlenecks in gathering and processing data and applying research results to real-life problems. Urbanism on Track showcases tracking experiments in urban studies, planning and design – from pedestrian navigation in Austria to Danish field tests, from TU Delft's Spatial Metro project to MIT's Real Time Rome and last but not least the Sense of the City project realised in Eindhoven. Urbanism on Track discusses the relevance of tracking for policy making, the possibilities of a new cartography and the implementation of tracking technologies in urban design and planning. This makes Urbanism on Track a unique book, setting the agenda for the structural embedment of research using tracking technologies in urbanism. BOOK DATA Publisher IOS Press // Editors Jeroen van Schaick, Stefan van der Spek, Frank van der Hoeven // Publication date December 2008 // Pages 200 // Duo-colour // ISBN 978-1586038175 // Price €70 / $99 Excl. VAT
description: Application of GPS data in Geographic Information Systems...33-45 Collaborative Map Generation...159-178 Mobile Pedestrian Navigation Systems...47-61 Tracking research...181-194 Tracking Visitors in Public Parks...63-74 Spatial Metro...77-97 Mobile Surveys...101-114 Our Daily Dance in Time and Space...117-125 The GPS Revolution in Spatial Research...15-21 A Method for Deriving Trip Destinations and Modes for GPS-based Travel Surveys...127-143 Tracking Technologies...23-30 Tracking Down the Effects of Travel Demand Policies...145-156 Introduction...5-13
Bioaccumulation of 17α-Ethinylestradiol in Fish
Creators: name: Al-Ansari, Ahmed
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: 17α- ethinylestradiol
bioaccumulation
fish

description: The active synthetic constituent of oral contraceptives 17α- ethinylestradiol (EE2) and its natural steroidal estrogen analogues are being released into the aquatic environment mainly via wastewater treatment plants (WWTPs). Although steroidal estrogens have been frequently reported in very low concentrations in the environment, they have been placed at the top of the list of endocrine disrupting chemicals (EDCs) for their high estrogenic activity in non-target aquatic species like fish and frogs. Almost 30 years worth of intensive research has moved the problem of endocrine disruption in the aquatic environment from being a hypothesis to a well-known cause-and-effect story. However, the fate and effects of many pharmaceuticals, including EE2, remain poorly understood. Thus, the main objective of this thesis was to investigate EE2 bioaccumulation in fish by field and laboratory studies. An optimized sample preparation and analytical method protocol was achieved to detect EE2 in its biologically active form in whole fish tissue at trace levels (ng/g). Shorthead redhorse suckers (ShRHS) (Moxostoma macrolepidotum) collected in proximity to a WWTP in the St. Clair River have significantly accumulated EE2 with an average of 1.5 ng/g. EE2 bioaccumulation was limited to fish exhibiting intersex and with induced vitellogenin (VTG). EE2 was absent in fish from a reference site. Positive correlations between EE2 and lipid content as well as "15N supported the hypothesis of EE2 bioaccumulation in wild ShRHSs. A wider survey was carried out to explore patterns of EE2 bioaccumulation in the pelagic and benthic food-wed of the St. Clair IV River, Ontario. In the WWTP effluents and nearby surface waters, EE2 levels were extremely low and below our method detection limits. All of the seven sampled species from different trophic levels and the sediment samples collected from the impacted sites and the reference sites did not have any measurable EE2 concentrations. A laboratory controlled study where male goldfish (Carassius auratus) were exposed to EE2 via water versus food demonstrated that fish can rapidly accumulate EE2 by both routes of exposure. The uptake constant for water was 45 h-1 and the bioconcentration factor for EE2 in fish was 377. The fast uptake rate of EE2 via water coincided with a much slower elimination rate constant of 0.0786 h-1. The assimilation efficiency of 0.106 for EE2 by goldfish was determined by EE2 dietary exposure, which was used to predict EE2 accumulation under different exposure scenarios. The work presented here was the first demonstration of EE2 bioaccumulation in wild fish and the first to model EE2 bioaccumulation from water and dietary exposure in laboratory-exposed fish.
Protein Intake at Twice the RDA in Older Men Increases Circulatory Concentrations of the Microbiome Metabolite Trimethylamine-N-Oxide (TMAO)
Creators: name: Mitchell, Sarah M.
name: Milan, Amber M.
name: Mitchell, Cameron J.
name: Gillies, Nicola A.
name: D’Souza, Randall F.
name: Zeng, Nina
name: Ramzan, Farha
name: Sharma, Pankaja
name: Knowles, Scott O.
name: Roy, Nicole C.
name: Sjödin, Anders
name: Wagner, Karl-Heinz
name: Zeisel, Steven H.
name: Cameron-Smith, David
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Higher dietary protein intake is increasingly recommended for the elderly; however, high protein diets have also been linked to increased cardiovascular disease (CVD) risk. Trimethylamine-N-oxide (TMAO) is a bacterial metabolite derived from choline and carnitine abundant from animal protein-rich foods. TMAO may be a novel biomarker for heightened CVD risk. The purpose of this study was to assess the impact of a high protein diet on TMAO. Healthy men (74.2 ± 3.6 years, n = 29) were randomised to consume the recommended dietary allowance of protein (RDA: 0.8 g protein/kg bodyweight/day) or twice the RDA (2RDA) as part of a supplied diet for 10 weeks. Fasting blood samples were collected pre- and post-intervention for measurement of TMAO, blood lipids, glucose tolerance, insulin sensitivity, and inflammatory biomarkers. An oral glucose tolerance test was also performed. In comparison with RDA, the 2RDA diet increased circulatory TMAO (p = 0.002) but unexpectedly decreased renal excretion of TMAO (p = 0.003). LDL cholesterol was increased in 2RDA compared to RDA (p = 0.049), but no differences in other biomarkers of CVD risk and insulin sensitivity were evident between groups. In conclusion, circulatory TMAO is responsive to changes in dietary protein intake in older healthy males.
Sismondi "astronomo d'uomini, non di stelle" e l'inedito giornale "Il Cannocchiale" (1796)
Creators: name: Bini, Alessio
Publisher: name: Alma Mater Studiorum, University of Bologna
Year: 2010

description: Sismondi                                "astronomo d'uomini, non di stelle" e l'inedito                                giornale "Il Cannocchiale" (1796)
Creating a Geodesign syllabus for landscape architecture in Denmark
Creators: name: Stysiak, Aleksander Andrzej
name: Zebitz Nielsen, Søren
name: Hare, Richard
name: Snizek, Bernhard
name: Skov-Petersen, Hans
Publisher: name: Research in Urbanism Series
Year: 2016

description: Geodesign provides a conceptual framework through which to understand relationships between geoscience and design. This paper takes its point of departure from the merger of the Departments of Geography and Geology and Forest, Landscape and Planning at the University of Copenhagen, and the subsequent approach taken to Geodesign as a means to realise potentials within the new academic structure. The aim is to address specifically how an on-going process of transforming the Landscape Architecture program has begun to integrate GIScience in a new way that fosters integration within and between disciplines. The approach to Geodesign will therefore be discussed in terms of cross-disciplinary dialogue and curriculum development. Emphasis will be placed on the results of the Geodesign Conference held at UCPH in November 2014 at which practitioners and academics came together to present extensive experiences and understandings of Geodesign. The conference was also the forum for discussion of the challenges and opportunities offered by Geodesign in the context of teaching.
description: Research in Urbanism Series, Vol. 4 (2016): Geo-Design: Advances in bridging geo-information technology, urban planning and landscape architecture
Fuel devolatilization in packed bed wood combustion
Creators: name: Girgis, Elisabeth
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Engineering, Chemical.

description: Packed bed combustion is the burning of solid fuel particles supported by a grate with the combustion air supplied from below. The combustion process is divided into four main stages: drying, devolatilization, volatiles combustion and char combustion. Biomasses proposed as renewal energy sources, such as wood, have a very high volatile content (∼80%). Therefore mechanistic models developed for the prediction of bed characteristics during biomass combustion must include devolatilization and volatile combustion stages in order to correctly predict combustion behaviour for better emissions control and process efficiency. A novel in-situ sampling method for tar, a major pyrolysis product, was developed that allows its concentration to be measured at various heights within the packed bed and appears to work satisfactorily. A series of experiments on packed bed combustion were conducted in a laboratory 'pot' type combustor. Two different equivalent particle size diameters (2.8 cm and 3.2 cm) of untreated spruce wood and two different airflow rates (0.025 kg/m2s and 0.03 kg/m 2s) were tested at a 22 cm bed height. Although the experimental data show scatter, the measurements indicated that pyrolysis occurred primarily within two particle diameters of the top of the bed, with large amounts of tar and CO and somewhat less CO2 being produced. This research also expanded a numerical model for packed bed combustion of solid fuels with the addition of a simple first order pyrolysis reaction, in which fixed proportions of the products were set as light volatiles of CO and CO2 with the balance as tar. The model results compared well with bed temperature, particle size and density measurement throughout the bed and gas concentration (CO, CO2, O2, and CH4) measurements in the reduction and oxidation zone.