cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Potential Pharmacological Chaperones for Cystathionine Beta-Synthase-Deficient Homocystinuria
Creators: name: Majtan, Tomas
name: Pey, Angel L.
name: Gimenez-Mascarell, Paula
name: Martínez-Cruz, Luis Alfonso
name: Szabó, Csaba
name: Kožich, Viktor
name: Kraus, Jan P.
Publisher: name: Health Research Alliance
Year: 2019
Subjects: subject: 60199 Biochemistry and Cell Biology not elsewhere classified
subject: FOS: Biological sciences
subject: Biological Techniques
subject: Biophysics
subject: Biotechnology
subject: 60107 Enzymes
subject: Genetics
subject: Medicine
subject: Molecular Biology
subject: Pharmacology

description: Classical homocystinuria (HCU) is the most common loss-of-function inbornerror of sulfur amino acid metabolism. HCU is caused by a deficiency in enzymaticdegradation of homocysteine, a toxic intermediate of methionine transformationto cysteine, chiefly due to missense mutations in the cystathionine betasynthase(CBS) gene. As with many other inherited disorders, the pathogenicmutations do not target key catalytic residues, but rather introduce structuralperturbations leading to an enhanced tendency of the mutant CBS to misfoldand either to form nonfunctional aggregates or to undergo proteasome-dependentdegradation. Correction of CBS misfolding would represent an alternative therapeuticapproach for HCU. In this review, we summarize the complex nature ofCBS, its multi-domain architecture, the interplay between the three cofactorsrequired for CBS function [heme, pyridoxal-50-phosphate (PLP), andS-adenosylmethionine (SAM)], as well as the intricate allosteric regulatorymechanism only recently understood, thanks to advances in CBS crystallography.While roughly half of the patients respond to treatment with a PLP precursorpyridoxine, many studies suggested usefulness of small chemicals, such aschemical and pharmacological chaperones or proteasome inhibitors, rescuingmutant CBS activity in cellular and animal models of HCU. Non-specific chemicalchaperones and proteasome inhibitors assist in mutant CBS folding processand/or prevent its rapid degradation, thus resulting in increased steady-state levelsof the enzyme and CBS activity. Recent interest in the field and availablestructural information will hopefully yield CBS-specific compounds, by usinghigh-throughput screening and computational modeling of novel ligands, improvingfolding, stability, and activity of CBS mutants.
Elastic property of single double-stranded DNA molecules: Theoretical study and comparison with experiments
Creators: name: Zhou, Haijun
name: Zhang, Yang
name: Ou-Yang, Zhong-can
Publisher: name: arXiv
Year: 2000
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Biological Physics (physics.bio-ph)
subject: Quantitative Biology (q-bio)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: This paper aims at a comprehensive understanding on the novel elastic property of double-stranded DNA (dsDNA) discovered very recently through single-molecule manipulation techniques. A general elastic model for double-stranded biopolymers is proposed and a new structural parameter called the folding angle $ϕ$ is introduced to characterize their deformations. The mechanical property of long dsDNA molecules is then studied based on this model, where the base-stacking interactions between DNA adjacent nucleotide basepairs, the steric effects of basepairs, and the electrostatic interactions along DNA backbones are taken into account. Quantitative results are obtained by using path integral method, and excellent agreement between theory and the observations reported by five major experimental groups are attained. The strong intensity of the base-stacking interactions ensures the structural stability of DNA, while the short-ranged nature of such interactions makes externally-stimulated large structural fluctuations possible. The entropic elasticity, highly extensibility, and supercoiling property of DNA are all closely related to this account. The present work also suggests the possibility that negative torque can induce structural transitions in highly extended DNA from right-handed B-form to left-handed configurations similar with Z-form configuration. Some formulae concerned with the application of path integral method to polymeric systems are listed in the Appendix.
description: 19 pages in latex format, including 7 EPS figures and 1 table. Submitted to PRE
Supplementary document for Functional OCT angiography reveals ultra-early retinal neurovascular dysfunction in diabetes with capillary resolution - 6256649.pdf
Creators: name: Liu, Kaiyuan
name: zhu, tiepei
name: Gao, MengQin
name: Yin, Xiaoting
name: Zheng, Rong
name: Yan, Yan
name: Gao, Lei
name: Ding, Zhihua
name: Ye, Juan
name: Li, Peng
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Biomedical Engineering not elsewhere classified

description: supplemental document
Separation of Quasiparticle and Phononic Heat Currents in YBCO
Creators: name: Zeini, B.
name: Freimuth, A.
name: Büchner, B.
name: Gross, R.
name: Kampf, A. P.
name: Kläser, M.
name: Müller-Vogt, G.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Measurements of the transverse (k_{xy}) and longitudinal (k_{xx}) thermal conductivity in high magnetic fields are used to separate the quasiparticle thermal conductivity (k_{xx}^{el}) of the CuO_2-planes from the phononic thermal conductivity in YBa_2Cu_3O_{7-δ}. k_{xx}^{el} is found to display a pronounced maximum below T_c. Our data analysis reveals distinct transport (τ) and Hall (τ_H) relaxation times below T_c: Whereas τis strongly enhanced, τ_H follows the same temperature dependence as above T_c.
title: Kooperation koordinieren, Forschung fördern und Versorgung verbessern: Das Hamburger Netzwerk für Versorgungsforschung
Creators: name: Bremer, Daniel
name: Busch, Susanne
name: Härter, Martin
name: Liedtke, Frank
name: Löwe, Bernd
name: Meusch, Andreas
name: Scherer, Martin
name: von dem Knesebeck, Olaf
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Am Universitätsklinikum Hamburg-Eppendorf (UKE) hat sich seit 2006 mit der Gründung des Center for Health Care Research (CHCR) die Versorgungsforschung (VF) als einer von fünf vom Wissenschaftsrat empfohlenen Forschungsschwerpunkten etabliert. Das CHCR ist ein Kooperationsverbund[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
Bilocal expansion of the Borel amplitude and the hadronic tau decay width
Creators: name: Cvetic, Gorazd
name: Lee, Taekoon
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The singular part of Borel transform of a QCD amplitude near the infrared renormalon can be expanded in terms of higher order Wilson coefficients of the operators associated with the renormalon. In this paper we observe that this expansion gives nontrivial constraints on the Borel amplitude that can be used to improve the accuracy of the ordinary perturbative expansion of the Borel amplitude. In particular, we consider the Borel transform of the Adler function and its expansion around the first infrared renormalon due to the gluon condensate. Using the next-to-leading order Wilson coefficient of the gluon condensate operator, we obtain an exact constraint on the Borel amplitude at the first IR renormalon. We then extrapolate, using judiciously chosen conformal transformations and Pade approximants, the ordinary perturbative expansion of the Borel amplitude in such a way that this constraint is satisfied. This procedure allows us to predict the $O(α_s^4)$ coefficient of the Adler function, which gives a result consistent with the estimate by Kataev and Starshenko using a completely different method. We then apply this improved Borel amplitude to the tau decay width, and obtain the strong coupling constant $α_s(M_Z) =0.1193 \pm 0.0007_{exp.} \pm 0.0010_{EW+CKM} \pm 0.0009_{meth.} \pm 0.0003_{evol.}$. We then compare this result with those of other resummation methods.
description: 30 pages, 4 eps-figures, revtex; version as appears in PRD; no major changes; more careful rounding of some numbers
Radiative deflection by spin effect in the quantum radiation-reaction regime
Creators: name: Geng, X. S.
name: Ji, L. L.
name: Shen, B. F.
name: Feng, B.
name: Guo, Z.
name: Han, Q. Q.
name: Qin, C. Y.
name: Wang, N. W.
name: Wang, W. Q.
name: Wu, Y. T.
name: Yan, X.
name: Yu, Q.
name: Zhang, L. G.
name: Xu, Z. Z.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The colliding between ultra-relativistic electrons and an ultra-intense laser pulse is a powerful approach to testify the physics in strong-field QED regime. By considering spin-dependent radiation-reaction during laser-electron collision we find anti-symmetric deflection of electrons with different spin states. We revealed that such deflection is induced by the non-zero work done by radiation-reaction force along field polarization-direction in a half-period of phase, which is larger for spin-anti-paralleled electrons and smaller for spin-paralleled electrons. The spin-projection on the magnetic field of an electron gets inversed in adjacent half-periods due to oscillating magnetic field and therefore the deflection due to spin-dependent radiation is accumulated rather than vanishing. The new mechanism provides an extra dimension to observe quantum radiation-reaction effect in the strong-field QED regime by measuring the anti-symmetric distribution.
description: 5 pages, 4 figures
Higgs studies in polarized gamma-gamma collisions
Creators: name: Fadin, V. S.
name: Khoze, V. A.
name: Martin, A. D.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The study of an intermediate mass Higgs boson, via the process gamma-gamma -> H -> bbbar from an initiallypolarized J_z = 0 state, has been advocated as an important feasible goal of a future photon linear collider. The crucial argument was the m_b^2/s suppression of the background process gamma-gamma (J_z = 0) -> bbbar. We critically review the contribution of the radiative background processes (in which the m_b^2/s suppression is absent) to the quasi-two-jet-like events with at least one, but preferably two, tagged energetic b jets. Within a complete study of the radiative processes, we find that a sizeable background contribution can come from the helicity-violating gamma-gamma (J_z = 0) -> bbbar process accompanied by soft gluon emission. These latter radiative corrections contain a new type of double logarithmic (DL) terms. We clarify the physical nature of these novel DL corrections. Despite the fact that the one-loop DL terms are comparable or even larger than the Born term, fortunately we find that the calculation of the cross section in the two-loop approximation is sufficient for a reliable evaluation of the background to the Higgs signal.
description: 36 pages of Latex file + 10 psfiles with figures
Pharmacokinetics and pharmacodynamics of PEGylated truncated human cystathionine beta-synthase for treatment of homocystinuria
Creators: name: Majtan, Tomas
name: Bublil, Erez M.
name: Insun Park
name: Arning, Erland
name: Bottiglieri, Teodoro
name: Glavin, Frank
name: Kraus, Jan P.
Publisher: name: Health Research Alliance
Year: 2019
Subjects: subject: 60199 Biochemistry and Cell Biology not elsewhere classified
subject: FOS: Biological sciences
subject: Biological Techniques
subject: Biotechnology
subject: 60107 Enzymes
subject: Medicine
subject: Molecular Biology
subject: Pharmacology

description: Aims: PEGylated human truncated cystathionine beta-synthase, lacking the C-terminal regulatory domain (PEGCBS),is a promising preclinical candidate for enzyme replacement therapy in homocystinuria (HCU). It wasdesigned to function as a metabolic sink to decrease the severely elevated plasma and tissue homocysteineconcentrations. In this communication, we evaluated pharmacokinetics (PK), pharmacodynamics (PD) and subchronictoxicity of PEG-CBS in homocystinuric mice, wild type rats and monkeys to estimate the minimumhuman efficacious dose for clinical trials.Main methods: Animal models received single or multiple doses of PEG-CBS. Activity of PEG-CBS and sulfuramino acid metabolites were determined in plasma and used to determine PK and PD.Key findings: The plasma half-lives of PEG-CBS after a single subcutaneous (SC) injection were approximately 20,44 and 73 h in mouse, rat and monkey, respectively. The SC administration of PEG-CBS resulted in a significantimprovement or full correction of metabolic imbalance in both blood and tissues of homocystinuric mice. The PDof PEG-CBS in mouse was dose-dependent, but less than dose-proportional, with the maximal efficacy achievedat 8 mg/kg. PEG-CBS was well-tolerated in mice and monkeys, but resulted in dose-dependent minimal-tomoderateinflammation at the injection sites and vacuolated macrophages in rats. Allometric scaling of animaldata was linear and the estimated human efficacious dose was determined as 0.66 mg/kg administered once aweek.Significance: These results provide critical preclinical data for the design of first-in-human PEG-CBS clinical trial.
Supplementary document for Fiber-integrated cantilever-based nanomechanical biosensors as a novel tool for rapid antibiotic susceptibility testing - 6347225.pdf
Creators: name: Zhou, Jie
name: Huang, Jiabin
name: Huang, Haoqiang
name: Zhao, Cong
name: Zou, Mengqiang
name: liu, Dejun
name: weng, xiaoyu
name: Liu, Liwei
name: Qu, Junle
name: Liu, Li
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: Supplemental Document for Fiber-integrated cantilever-based nanomechanical biosensors as a novel tool for rapid antibiotic susceptibility testing
Kondo effect in AC transport through Quantum dots
Creators: name: Lopez, Rosa
name: Aguado, Ramon
name: Platero, Gloria
name: Tejedor, Carlos
Publisher: name: arXiv
Year: 1998
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: A theory of the Kondo effect in quantum dots at zero temperature in the presence of arbitrary intense AC potentials is presented.We generalize the Friedel-Langreth sum rule to take care of charge conservation and propose a consistent procedure to study a time dependent Anderson Hamiltonian. The effect of the AC potential on both the quantum dot density of states and the linear conductance shows the importance of using a theory which describes intradot finite interaction and nonperturbative effects.
description: 11 RevTex pages, 4 Postscript figures, submmited to PRL
title: Zur Etablierung einer translationalen Zusammenarbeit zwischen einer Praxis- und einer Forschungseinrichtung
Creators: name: Purwins, Daniel
name: Reuther, Sven
name: Gioti, Irini
name: Schön, Sebastian
name: Teupen, Sonja
name: Roes, Martina
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die bisherige projektbezogene Zusammenarbeit zwischen einem in kommunaler Trägerschaft befindlichen Anbieter quartiersnaher Unterstützungsleistungen für ältere Menschen (Praxiseinrichtung) und einer Forschungseinrichtung (Versorgungsforschung) war vor allem dadurch charakterisiert,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
Consistent dust and gas models for protoplanetary disks IV. A panchromatic view of protoplanetary disks
Creators: name: Dionatos, O.
name: Woitke, P.
name: Guedel, M.
name: Degroote, P.
name: Liebhart, A.
name: Anthonioz, F.
name: Antonellini, S.
name: Baldovin-Saavedra, C.
name: Carmona, A.
name: Dominik, C.
name: Greaves, J.
name: Ilee, J. D.
name: Kamp, I.
name: Menard, F.
name: Min, M.
name: Pinte, C.
name: Rab, C.
name: Rigon, L.
name: Thi, W. F.
name: Waters, L. B. F. M.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Consistent modeling of protoplanetary disks requires the simultaneous solution of both continuum and line radiative transfer, heating/cooling balance between dust and gas and, of course, chemistry. Such models depend on panchromatic observations that can provide a complete description of the physical and chemical properties and energy balance of protoplanetary systems. Along these lines we present a homogeneous, panchromatic collection of data on a sample of 85 T Tauri and Herbig Ae objects for which data cover a range from X-rays to centimeter wavelengths. Datasets consist of photometric measurements, spectra, along with results from the data analysis such as line fluxes from atomic and molecular transitions. Additional properties resulting from modeling of the sources such as disc mass and shape parameters. dust size and PAH properties are also provided for completeness. Targets were selected based on their properties data availability. Data from more than 50 different telescopes and facilities were retrieved and combined in homogeneous datasets directly from public data archives or after being extracted from more than 100 published articles. X-ray data for a subset of 56 sources represent an exception as they were reduced from scratch and are presented here for the first time. Compiled datasets along with a subset of continuum and emission-line models are stored in a dedicated database and distributed through a publicly accessible online system. All datasets contain metadata descriptors that allow to backtrack them to their original resources. The graphical user interface of the online system allows the user to visually inspect individual objects but also compare between datasets and models. It also offers to the user the possibility to download any of the stored data and metadata for further processing.
description: 32 pages, 11 figures, A&A accepted
Precision Physics Near LEP Shutdown and Evolutionary Developments
Creators: name: Passarino, G.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The most celebrated aspects of precision physics are briefly summarized. New ideas are also introduced that may lead to further developments in the field of radiative corrections, with special emphasis to multi-loop numerical evaluation and to a correct treatment of QED radiation for arbitrary processes.
description: 13 pages(Latex), 2 figures. Presented at 50 Years of Electroweak Physics, a Symposium in honor of Professor Alberto Sirlin's 70th Birthday, NYU, October 27-28, 2000
SUSM: a scenario-based urban growth simulation model using remote sensing data
Creators: name: Kantakumar, Lakshmi N.
name: Shamita Kumar
name: Schneider, Karl
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: The introduction of the Foreign Direct Investment (FDI) policy in 1991 made India one of the fastest growing economies in the world. This has had a profound effect on India’s urbanization. The rapid urbanization of Indian cities poses a threat to natural and social environments, as expansion of the cities often outpaces the urban planning process. Thus, smart and strategic planning processes that use current and easily available datasets in combination with future urbanization scenarios are needed. To this end, we developed the scenario-based urban growth simulation model (SUSM), which can be used for impact analysis of different planning measures in both spatial and temporal contexts. SUSM uses remote sensing derived inputs, such as land use maps, slope, roads and centres of urban areas along with urban development scenarios. It uses logistic regression for calibration and a constrained stochastic cellular automaton for simulation of urban growth. SUSM is tested in one of the fastest growing urban agglomerations of India: The Pune metropolis, which covers an area of 1642 km2. SUSM is calibrated using urban growth maps derived from LANDSAT satellite images from 1992 to 2001. Subsequently, SUSM was used to simulate urban growth of Pune for 2013. A comparison of the SUSM simulation result with the actually measured urban growth derived from a LANDSAT 8 scene from 2013 is used to validate SUSM and to assess the effect of urban plans upon the growth of Pune. Our results show that: (i) SUSM is capable of predicting the location of future urbanization with an accuracy of 79% and a fuzzy kappa index of agreement 0.81; (ii) inclusion of official urban development plans as input for SUSM did not provide a better agreement with the observed growth; (iii) SUSM, parameterized with remote sensing data, can be used effectively to understand urban growth and assess the effects of alternative urban development plans in terms of the spatial expansion of cities.
Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor
Creators: name: Wang, Hanshu
name: Lin, Yu
name: Chen, RongRong
name: Zhu, Yu
name: Wang, Hongqiang
name: Li, Shengxian
name: Yu, Lei
name: Zhang, Kaishu
name: Liu, Yujie
name: Jing, Tao
name: Sun, Fei
Publisher: name: Zenodo
Year: 2024
Subjects: seminal extracellular vesicles
endometrial receptivity
LIF
integrin
Adhesion

description: Seminal extracellular vesicles (EVs) contain different subgroups that have diverse effects on sperm function. However, the effect of seminal EVs—especially its subgroups, on the endometrial receptivity was largely unknown. Here, we found that the seminal EVs could be divided into high-density EV (EV-H), medium density EV (EV-M), and low-density EV (EV-L), after purification using iodixanol. Then we demonstrated that EV-H could promote the expression and secretion of leukemia inhibitor factor (LIF) in human endometrial cells. In EV-H-treated endometrial cells, we identified 1274 differentially expressed genes (DEGs). DEGs were enriched in cell adhesion and AKT, STAT3 pathways. Therefore, we illustrated that EV-H enhanced the adhesion of human choriocarcinoma JAr cell spheroids to endometrial cells through the LIF-STAT3 pathway. Collectively, our findings indicated that seminal EV-H could regulate endometrial receptivity through the LIF pathway, which would provide novel insights into male fertility.
description: Funding provided by: The National Key Research and Development Program of China*Crossref Funder Registry ID: Award Number: 2021YFC2700200
Funding provided by: The Key Research and Development Program of Zhejiang Province*Crossref Funder Registry ID: Award Number: 2023C03035
Funding provided by: The Key Research and Development Program of Ningxia Hui Autonomous Region*Crossref Funder Registry ID: Award Number: 2021BEG02029
Funding provided by: Shandong Provincial Natural Science FoundationCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100007129Award Number: ZR2023QH491
title: Welche individuellen und organisationalen Faktoren stehen in Zusammenhang mit „Psychological Safety“ von Pflegekräften auf Intensivstationen? – Ergebnisse einer Mehrebenenanalyse
Creators: name: Hillen, Hendrik
name: Kuntz, Ludwig
name: Pfaff, Holger
name: Scholten, Nadine
name: Seibert, Melissa
name: Wittland, Michael
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Patientensicherheit ist unter anderem auf das Verhalten und die Einstellungen der Mitarbeitenden im Krankenhaus zurückzuführen. Häufig müssen Mitarbeitende spontan entscheiden, ob sie ihre Bedenken im Klinikalltag (z.B. hinsichtlich einer bestimmten Behandlung) offen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
Spin-flip transitions between Zeeman sublevels in semiconductor quantum dots
Creators: name: Khaetskii, Alexander V.
name: Nazarov, Yuli V.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We have studied spin-flip transitions between Zeeman sublevels in GaAs electron quantum dots. Several different mechanisms which originate from spin-orbit coupling are shown to be responsible for such processes. It is shown that spin-lattice relaxation for the electron localized in a quantum dot is much less effective than for the free electron. The spin-flip rates due to several other mechanisms not related to the spin-orbit interaction are also estimated.
description: RevTex, 7 pages (extended journal version, PRB, in press)
Exact gate decompositions for photonic quantum computing
Creators: name: Kalajdzievski, Timjan
name: Arrazola, Juan Miguel
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a method for decomposing continuous-variable operations into a universal gate set, without the use of any approximations. We fully characterize a set of transformations admitting exact decompositions and describe a process for obtaining them systematically. Gates admitting these decompositions can be synthesized exactly, using circuits that are several orders of magnitude smaller than those achievable with previous methods. Our method relies on strategically using unitary conjugation and a lemma to the Baker-Campbell-Hausdorff formula to derive new exact decompositions from previously known ones, leading to exact decompositions for a large class of gates. We demonstrate the wide applicability of these exact gate decompositions by identifying several quantum algorithms and simulations of bosonic systems that can be implemented with higher precision and shorter circuit depths using our techniques.
title: Transitions towards car-free cities
Creators: name: Van Waas, Willem
Publisher: name: Student Undergraduate Research E-journal!
Year: 2018

description: As various cities around the world are implementing car-free policy, the need to understand it from a dynamic point of view becomes more pronounced. This paper sheds more light on the reasons to go car-free as forces of change, while further analyzing the inhibitors and dynamics of transitions towards car-free cities. Reasons to drive can be conceptualized as intrinsic and extrinsic, each with its own relevance in the light of transitions. At the same time, the dynamic processes of enabling and implementation are conceptualized in order to move towards a more realistic view of the complexities of these transitions.
description: Student Undergraduate Research E-journal!, Vol 4 (2018): Student Research Conference 2018
title: Gute Versorgung trotz Fachkräftemangel? Eine Herausforderung für die Zukunft
Creators: name: Riedlinger, Isabelle
name: Lämmel, Nora
name: Müller, Dorothee
name: Reiber, Karin
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Der Pflegefachkraftmangel in Deutschland ist derzeit eines der meist diskutierten Themen. Im Hinblick auf die zukünftige pflegerische Versorgung ist ein „weiter so“ nicht möglich [ref:1]. Dabei geht es nicht nur um die Belastung und Gesundheit der Fachkräfte.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
Inverse Amplitude Method and Chiral Zeros
Creators: name: Hannah, Torben
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The inverse amplitude method has previously been successfully applied to $ππ$ scattering in order to extend the range of applicability of chiral perturbation theory. However, in order to take the chiral zeros into account systematically, the previous derivation of the inverse amplitude method has to be modified. It is shown how this can be done to both one and two loops in the chiral expansion. In the physical region, the inclusion of these chiral zeros has very little significance, whereas they become essential in the sub-threshold region. Finally, the crossing properties of the inverse amplitude method are investigated in the sub-threshold region.
description: 5 pages, 2 figs, REVTeX, Phys. Rev. D version
АЛЬТЕРНАТИВНЫЕ МЕТОДЫ РАЗРЕШЕНИЯ СПОРОВ В СФЕРЕ ГОСУДАРСТВЕННЫХ ЗАКУПОК
Creators: name: Рамазанова, Эльвира
Publisher: name: Zenodo
Year: 2024

description: Государственные закупки на сегодняшний день составляют весомую часть экономики любой страны. Принцип эффективности государственных закупок занимает приоритетное место в проведении реформ. Наряду с этим, расширение границ применения государственных закупок создаёт импульс для проявлений недобросовестного поведения участников государственных закупок и возникновения споров между их субъектами.
Finite size scaling for a first order transition where a continuous symmetry is broken: The spin-flop transition in the 3D XXZ Heisenberg antiferromagnet
Creators: name: Xu, Jiahao
name: Tsai, Shan-Ho
name: Landau, D. P.
name: Binder, K.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Finite size scaling for a first order phase transition where a continuous symmetry is broken is developed using an approximation of Gaussian probability distributions with a phenomenological "degeneracy" factor included. Predictions are compared with data from Monte Carlo simulations of the three-dimensional, XXZ Heisenberg antiferromagnet in a field in order to study the finite size behavior on a $L \times L \times L$ simple cubic lattice for the first order "spin-flop" transition between the Ising-like antiferromagnetic state and the canted, XY-like state. Our theory predicts that for large linear dimension $L$ the field dependence of all moments of the order parameters as well as the fourth-order cumulants exhibit universal intersections. Corrections to leading order should scale as the inverse volume. The values of these intersections at the spin-flop transition point can be expressed in terms of a factor $q$ that characterizes the relative degeneracy of the ordered phases. Our theory yields $q=π$, and we present numerical evidence that is compatible with this prediction. The agreement between the theory and simulation implies a heretofore unknown universality can be invoked for first order phase transitions.
description: 20 pages, 21 figures
title: Ergebnisse einer Arbeitgeberbefragung zur Implementierung des betrieblichen Eingliederungsmanagements in Thüringen. Ein Beitrag zur arbeitsmedizinischen Versorgungsforschung in Deutschland
Creators: name: Amler, Nadja
name: Quittkat, Christine
name: Sedlazcek, Sabine
name: Frassek, Anna-Lena
name: Fischmann, Wolfgang
name: Nesseler, Thomas
name: Letzel, Stephan
name: Drexler, Hans
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Vor dem Hintergrund der demographischen Entwicklung und der damit zusammenhängenden veränderten Zusammensetzung der Belegschaften gewinnt die Wiedereingliederung chronisch- bzw. langzeitkranker Beschäftigter zunehmend an Bedeutung. Mit dem Betrieblichen Eingliederungsmanagement[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
title: A qualitative review of the risks of traumatic experiences for emergency personnel and coping management in international view
Creators: name: Mann, Bernhard
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Emergency personnel are constantly exposed to traumatic experiences in their work environment. “Emergency personnel” means any persons, paid or volunteer, who receive calls for dispatch of police, fire, or emergency medical service personnel, and includes law-enforcement officers, firefighters,[for full text, please go to the a.m. URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
Electrodynamics of a Clean Vortex Lattice
Creators: name: Atkinson, W. A.
name: MacDonald, A. H.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We report on a microscopic evaluation of electrodynamic response for the vortex lattice state of a model s-wave superconductor. Our calculation accounts self-consistently for both quasiparticle and order parameter response and establishes the collective nature of linear response in the clean limit. We discuss the effects of homogeneous and inhomogeneous pinning on the optical conductivity and the penetration depth, and comment on the relationship between macroscopic and local penetration depths. We find unexpected relationships between pinning arrangements and conductivity due to the strongly non-local response.
description: 4 pages, 2 figures
Quantum synchronization of two mechanical oscillators in coupled optomechanical systems with Kerr nonlinearity
Creators: name: Qiao, Guo-jian
name: Gao, Hui-xia
name: Liu, Hao-di
name: Yi, X. X.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the quantum synchronization phenomena of two mechanical oscillators of different frequencies in two optomechanical systems under periodically modulating cavity detunings or driving amplitudes, which can interact mutually through an optical fiber or a phonon tunneling. The cavities are filled with Kerr-type nonlinear medium. It is found that, no matter which the coupling and periodically modulation we choose, both of the quantum synchronization of nonlinear optomechanical system are more appealing than the linear optomechanical system. It is easier to observe greatly enhanced quantum synchronization with Kerr nonlinearity. In addition, the different influences on the quantum synchronization between the two coupling ways and the two modulating ways are compared and discussed.
description: 12pages, 9figures
A Note on Supersymmetric WZW term in Four Dimensions
Creators: name: Nitta, Muneto
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We reconsider the supersymmetric Wess-Zumino-Witten (SWZW) term in four dimensions. It has been known that the manifestly supersymmetric form of the SWZW term includes derivative terms on auxiliary fields, the highest components of chiral superfields, and then we cannot eliminate them by their equations of motion. We discuss a possibility for the elimination of such derivative terms by adding total derivative terms. Although the most of derivative terms can be eliminated as in this way, we find that all the derivative terms can be canceled, if and only if an anomalous term in SWZW term vanishes. As a byproduct, we find the first example of a higher derivative term free from such a problem.
description: LaTeX, 10 pages, no figures, typos corrected, references added, accepted for publication in Modern Physics Letters A
title: ÐÐ´Ð¾ÑÐ¾Ð²ÑÐµ - Ð¾ÑÐ½Ð¾Ð²Ð° ÑÐµÐ»Ð¾Ð²ÐµÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿Ð¾ÑÐµÐ½ÑÐ¸Ð°Ð»Ð°: Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¸ Ð¿ÑÑÐ¸ Ð¸Ñ ÑÐµÑÐµÐ½Ð¸Ñ
title: ÑÑÑÐ´Ñ Ð¿ÑÑÐ¾Ð¹ ÐÑÐµÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð¹ Ð½Ð°ÑÑÐ½Ð¾-Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ð¸ Ñ Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐ¼ ÑÑÐ°ÑÑÐ¸ÐµÐ¼, 25-27 Ð½Ð¾ÑÐ±ÑÑ 2010 Ð³.
titleType: Subtitle
Creators: name: "ÐÐ´Ð¾ÑÐ¾Ð²ÑÐµ-Ð¾ÑÐ½Ð¾Ð²Ð° ÑÐµÐ»Ð¾Ð²ÐµÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿Ð¾ÑÐµÐ½ÑÐ¸Ð°Ð»Ð°: Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¸ Ð¿ÑÑÐ¸ Ð¸Ñ  ÑÐµÑÐµÐ½Ð¸Ñ", ÐÑÐµÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ°Ñ Ð½Ð°ÑÑÐ½Ð¾-Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ°Ñ ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ñ Ñ Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐ¼ ÑÑÐ°ÑÑÐ¸ÐµÐ¼ (5; 2010; Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³)
name: "ÐÐ¸ÑÐ¾Ð³Ð¾Ð²ÑÐºÐ°Ñ Ñ Ð¸ÑÑÑÐ³Ð¸ÑÐµÑÐºÐ°Ñ Ð½ÐµÐ´ÐµÐ»Ñ", Ð²ÑÐµÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¸Ð¹ ÑÐ¾ÑÑÐ¼ Ðº 200-Ð»ÐµÑÐ¸Ñ Ð. Ð. ÐÐ¸ÑÐ¾Ð³Ð¾Ð²Ð° (2010; Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³)
Publisher: name: ÐÐ·Ð´-Ð²Ð¾ ÐÐ¾Ð»Ð¸ÑÐµÑÐ½. ÑÐ½-ÑÐ°
Year: 2010
Subjects: Ð¼ÐµÐ´Ð¸ÑÐ¸Ð½Ð°
ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ð¸

description: Ð ÐºÐ½Ð¸Ð³Ðµ Ð¾Ð¿ÑÐ±Ð»Ð¸ÐºÐ¾Ð²Ð°Ð½Ñ ÑÐµÐ·Ð¸ÑÑ Ð´Ð¾ÐºÐ»Ð°Ð´Ð¾Ð² Ð¸ ÑÑÐ°ÑÐµÐ¹, Ð¾ÑÑÐ°Ð¶Ð°ÑÑÐ¸Ñ ÑÑÐ¾Ð²ÐµÐ½Ñ Ð¸ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÑ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°ÐµÐ¼Ð¾ÑÑÐ¸ Ð¿Ð¾ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐ¼ Ð³ÑÑÐ¿Ð¿Ð°Ð¼ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ð¹, Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÐ¸ Ð¸Ñ ÐºÐ¾Ð½ÑÐµÑÐ²Ð°ÑÐ¸Ð²Ð½Ð¾Ð³Ð¾ Ð¸ ÑÐ¸ÑÑÑÐ³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð»ÐµÑÐµÐ½Ð¸Ñ. ÐÑÐ¸Ð²Ð¾Ð´ÑÑÑÑ ÑÐ²ÐµÐ´ÐµÐ½Ð¸Ñ Ð¾ Ð´ÐµÐ¼Ð¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¿ÑÐ¾ÑÐµÑÑÐ°Ñ Ð² Ð½Ð°ÑÐµÐ¹ ÑÑÑÐ°Ð½Ðµ. ÐÑÐµÐ´Ð»Ð°Ð³Ð°ÑÑÑÑ Ð¿ÑÑÐ¸ ÑÐ»ÑÑÑÐµÐ½Ð¸Ñ Ð·Ð´Ð¾ÑÐ¾Ð²ÑÑ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð¸Ñ Ð² ÑÑÑÐ°Ð½Ðµ Ð¸ ÐµÐµ Ð¾ÑÐ´ÐµÐ»ÑÐ½ÑÑ ÑÐµÐ³Ð¸Ð¾Ð½Ð°Ñ, Ð³Ð¾ÑÐ¾Ð´Ð°Ñ Ð¸ ÑÑÑÐµÐ¶Ð´ÐµÐ½Ð¸ÑÑ.
Two-Loop Corrections to the Electromagnetic Vertex for Energies close to Threshold
Creators: name: Hoang, A. H.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Two-loop contributions to the electromagnetic form factors are calculated in the kinematic regime close to the fermion-antifermion threshold. The results are presented in an expansion in the velocity $β$ of the fermions in the c.m. frame up to next-to-next-to leading order in $β$. The existence of a new Coulomb singularity logarithmic in $β$, which is closely related to the $O(α^2\lnα)$ corrections known from positronium decays, is demonstrated. It is shown that due to this Coulomb singularity $O(α^2)$ relativistic corrections to the non-relativistic cross section of heavy fermion-antifermion pair production in $e^+e^-$ annihilation cannot be determined by means of conventional multi-loop perturbation theory.
description: 13 pages, latex, no figures
Metabolic profiles of oligosaccharides derived from four microbial polysaccharides by faecal inocula from type 2 diabetes patients
Creators: name: Xu, Jingjing
name: Liu, Weibao
name: Wu, Jianrong
name: Wang, Wen
name: Wang, Zhuoping
name: Yu, Xun
name: Zhang, Hongtao
name: Zhu, Li
name: Zhan, Xiaobei
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: In vitro digestion of curdlan oligosaccharides (COSs), pullulan oligosaccharides (POSs), xanthan gum oligosaccharides (XGOSs) and gellan gum oligosaccharides (GGOSs) was investigated. These four oligosaccharides showed resistance to simulated saliva and gastric and small intestinal fluid. In further fermentation with faecal microbiota from healthy subjects and type 2 diabetes (T2D) patients, COS fermentation significantly increased the abundance of Bifidobacterium spp. and Lactobacillus spp. and the production of short-chain fatty acids in healthy and T2D groups. Digestion of XGOS enhanced the growth of the Clostridium leptum subgroup and significantly increased butyric acid production in healthy and T2D groups. Sole fermentation with COS, POS, XGOS and GGOS exhibited different metabolic profiles between healthy and T2D groups, and more small molecule polyols were produced in the T2D group than in the healthy group. This study provides a novel perspective on the reconstruction of gut microbiota and metabolism by POS, COS, GGOS and XGOS intervention.
Comparison of the GPVI inhibitors losartan and honokiol
Creators: name: Marie-Blanche Onselaer
name: Nagy, Magdolna
name: Pallini, Chiara
name: Pike, Jeremy A
name: Perrella, Gina
name: Quintanilla, Lourdes Garcia
name: Eble, Johannes A
name: Poulter, Natalie S.
name: Heemskerk, Johan W.M.
name: Watson, Steve P
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Losartan and honokiol are small molecules which have been described to inhibit aggregation of platelets by collagen. Losartan has been proposed to block clustering of GPVI but not to affect binding of collagen. Honokiol has been reported to bind directly to GPVI but only at a concentration that is three orders of magnitude higher than that needed for inhibition of aggregation. The mechanism of action of both inhibitors is so far unclear. In the present study, we confirm the inhibitory effects of both agents on platelet aggregation by collagen and show that both also block the aggregation induced by the activation of CLEC-2 or the low affinity immune receptor FcγRIIa at similar concentrations. For GPVI and CLEC-2, this inhibition is associated with a reduction in protein tyrosine phosphorylation of multiple proteins including Syk. In contrast, on a collagen surface, spreading of platelets and clustering of GPVI (measured by single molecule localisation microscopy) was not altered by losartan or honokiol. Furthermore, in flow whole-blood, both inhibitors suppressed the formation of multi-layered platelet thrombi at arteriolar shear rates at concentrations that hardly affect collagen-induced platelet aggregation in platelet rich plasma. Together, these results demonstrate that losartan and honokiol have multiple effects on platelets which should be considered in the use of these compounds as anti-platelet agents.
title: ÐÐ´Ð¾ÑÐ¾Ð²ÑÐµ - Ð¾ÑÐ½Ð¾Ð²Ð° ÑÐµÐ»Ð¾Ð²ÐµÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿Ð¾ÑÐµÐ½ÑÐ¸Ð°Ð»Ð°: Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¸ Ð¿ÑÑÐ¸ Ð¸Ñ ÑÐµÑÐµÐ½Ð¸Ñ
title: ÑÑÑÐ´Ñ ÑÐµÑÐ²ÐµÑÑÐ¾Ð¹ ÐÑÐµÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð¹ Ð½Ð°ÑÑÐ½Ð¾-Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ð¸ Ñ Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐ¼ ÑÑÐ°ÑÑÐ¸ÐµÐ¼, 24-26 Ð½Ð¾ÑÐ±ÑÑ 2009 Ð³.
titleType: Subtitle
Creators: name: "ÐÐ´Ð¾ÑÐ¾Ð²ÑÐµ-Ð¾ÑÐ½Ð¾Ð²Ð° ÑÐµÐ»Ð¾Ð²ÐµÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿Ð¾ÑÐµÐ½ÑÐ¸Ð°Ð»Ð°: Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¸ Ð¿ÑÑÐ¸ Ð¸Ñ  ÑÐµÑÐµÐ½Ð¸Ñ", Ð²ÑÐµÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ°Ñ Ð½Ð°ÑÑÐ½Ð¾-Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ°Ñ ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ñ Ñ Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐ¼ ÑÑÐ°ÑÑÐ¸ÐµÐ¼ (4; 2009; Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³)
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2009
Subjects: Ð¼ÐµÐ´Ð¸ÑÐ¸Ð½Ð°
Ð·Ð´Ð¾ÑÐ¾Ð²ÑÐµ

description: Ð ÐºÐ½Ð¸Ð³Ðµ Ð¾Ð¿ÑÐ±Ð»Ð¸ÐºÐ¾Ð²Ð°Ð½Ñ ÑÐµÐ·Ð¸ÑÑ Ð´Ð¾ÐºÐ»Ð°Ð´Ð¾Ð² Ð¸ ÑÑÐ°ÑÐµÐ¹, Ð¾ÑÑÐ°Ð¶Ð°ÑÑÐ¸Ñ ÑÑÐ¾Ð²ÐµÐ½Ñ Ð¸ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÑ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°ÐµÐ¼Ð¾ÑÑÐ¸ Ð¿Ð¾ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐ¼ Ð³ÑÑÐ¿Ð¿Ð°Ð¼ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ð¹, Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÐ¸ Ð¸Ñ ÐºÐ¾Ð½ÑÐµÑÐ²Ð°ÑÐ¸Ð²Ð½Ð¾Ð³Ð¾ Ð¸ ÑÐ¸ÑÑÑÐ³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð»ÐµÑÐµÐ½Ð¸Ñ. ÐÑÐ¸Ð²Ð¾Ð´ÑÑÑÑ ÑÐ²ÐµÐ´ÐµÐ½Ð¸Ñ Ð¾ Ð´ÐµÐ¼Ð¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¿ÑÐ¾ÑÐµÑÑÐ°Ñ Ð² Ð½Ð°ÑÐµÐ¹ ÑÑÑÐ°Ð½Ðµ. ÐÑÐµÐ´Ð»Ð°Ð³Ð°ÑÑÑÑ Ð¿ÑÑÐ¸ ÑÐ»ÑÑÑÐµÐ½Ð¸Ñ Ð·Ð´Ð¾ÑÐ¾Ð²ÑÑ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð¸Ñ Ð² ÑÑÑÐ°Ð½Ðµ Ð¸ ÐµÐµ Ð¾ÑÐ´ÐµÐ»ÑÐ½ÑÑ ÑÐµÐ³Ð¸Ð¾Ð½Ð°Ñ, Ð³Ð¾ÑÐ¾Ð´Ð°Ñ Ð¸ ÑÑÑÐµÐ¶Ð´ÐµÐ½Ð¸ÑÑ.
No Padding Please: Efficient Neural Handwriting Recognition
Creators: name: Wenniger, Gideon Maillette de Buy
name: Schomaker, Lambert
name: Way, Andy
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: Neural handwriting recognition (NHR) is the recognition of handwritten text with deep learning models, such as multi-dimensional long short-term memory (MDLSTM) recurrent neural networks. Models with MDLSTM layers have achieved state-of-the art results on handwritten text recognition tasks. While multi-directional MDLSTM-layers have an unbeaten ability to capture the complete context in all directions, this strength limits the possibilities for parallelization, and therefore comes at a high computational cost. In this work we develop methods to create efficient MDLSTM-based models for NHR, particularly a method aimed at eliminating computation waste that results from padding. This proposed method, called example-packing, replaces wasteful stacking of padded examples with efficient tiling in a 2-dimensional grid. For word-based NHR this yields a speed improvement of factor 6.6 over an already efficient baseline of minimal padding for each batch separately. For line-based NHR the savings are more modest, but still significant. In addition to example-packing, we propose: 1) a technique to optimize parallelization for dynamic graph definition frameworks including PyTorch, using convolutions with grouping, 2) a method for parallelization across GPUs for variable-length example batches. All our techniques are thoroughly tested on our own PyTorch re-implementation of MDLSTM-based NHR models. A thorough evaluation on the IAM dataset shows that our models are performing similar to earlier implementations of state-of-the-art models. Our efficient NHR model and some of the reusable techniques discussed with it offer ways to realize relatively efficient models for the omnipresent scenario of variable-length inputs in deep learning.
ENSURING THE RULE OF LAW IN THE IMPLEMENTATION OF ENERY INVESTMENTS
Creators: name: Shpinev Iu.
Publisher: name: The Scientific Heritage
Year: 2021
Subjects: economy
prosecutor's office
prosecutor's supervision
energy
investment
coal industry
oil industry.

description: This article examines the investment component of the Russian energy sector, as well as the role of prosecutor's supervision in the industry under consideration. The author concludes that despite one of the leading positions of our country in the global energy market, in the near future this industry may face a significant shortage of investment. This is due both to the general investment risks of the industry, and to the negative political and economic attitude of the leading world powers to our country. A significant factor that can negatively affect the investment attractiveness of the industry is the growing desire of developed countries to develop a "green economy". Under such circumstances, the role of the prosecutor's supervision of compliance with investment legislation in the economy is significantly increased, based on the positive experience of the prosecutor's supervision in the field of investment activities in the territories of advanced socio-economic development in the Far Eastern Federal District, including the creation of an interdepartmental working group on investor protection.
The COS CGM Compendium. II: Metallicities of the Partial and Lyman Limit Systems at z<1
Creators: name: Wotta, Christopher B.
name: Lehner, Nicolas
name: Howk, J. Christopher
name: O'Meara, John
name: Oppenheimer, Benjamin D.
name: Cooksey, Kathy L.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the results from our COS circumgalactic medium (CGM) compendium (CCC), a survey of the CGM at z<1 using HI-selected absorbers with 1519 have mostly -1
description: Resubmitted to ApJ after the first referee report