title: ÐÑÐµÐ½ÐºÐ° Ð¼Ð¸ÐºÑÐ¾Ð±Ð¸Ð¾Ð¼Ð° ÑÐ¾Ð»ÑÑÐ¾Ð³Ð¾ ÐºÐ¸ÑÐµÑÐ½Ð¸ÐºÐ° Ñ Ð¼ÑÑÐµÐ¹ Ñ Ð»Ð¸Ð¼ÑÐ¾ÑÐ°ÑÐºÐ¾Ð¼Ð¾Ð¹ ÐÐÐ-1, ÑÑÐ°Ð½ÑÐ¿Ð»Ð°Ð½ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð¹ Ð¸Ð½ÑÑÐ°ÐºÑÐ°Ð½Ð¸Ð°Ð»ÑÐ½Ð¾
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Assessment of the microbiome of the large intestine in mice with lymphosarcoma LIOâ1 transplanted intracranially
Creators: name: Ð¢ÑÐµÐ¼Ð°ÑÐ¾Ð²Ð°, ÐÐ»ÐµÐºÑÐ°Ð½Ð´ÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: Ð¾Ð½ÐºÐ¾Ð»Ð¾Ð³Ð¸Ñ
Ð¼Ð¸ÐºÑÐ¾Ð±Ð¸Ð¾Ð»Ð¾Ð³Ð¸Ñ
Ð±Ð°ÐºÑÐµÑÐ¸Ð¸
Ð¶ÐµÐ»ÑÐ´Ð¾ÑÐ½Ð¾-ÐºÐ¸ÑÐµÑÐ½ÑÐ¹ ÑÑÐ°ÐºÑ
Ð»Ð¸Ð¼ÑÐ¾ÑÐ°ÑÐºÐ¾Ð¼Ð°
Ð¼Ð°ÑÑ-ÑÐ¿ÐµÐºÑÑÐ¾Ð¼ÐµÑÑÐ¸Ñ
Ð¼Ð¸ÐºÑÐ¾Ð±Ð¸Ð¾Ð¼
oncology
microbiology
bacteria
gastrointestinal tract
lymphosarcoma
mass-spectrometry
microbiome

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description: This work is devoted to the study of the effect of a tumor and a cytostatic drug on the colon microbiome of experimental animals. Tasks that were solved during the research: â¢ Fecal sampling of experimental animals; â¢Conducting primary seeding of biological material on selective solid nutrient media; â¢ Morphological assessment of microbial colony growth; â¢Identification of microorganisms using the MALDIâTOF AUTOF MS 1000 microbiological mass spectrometer; â¢Conducting histological examination of the colon of experimental animals; â¢ Analysis of the results obtained. The work was carried out on the basis of NVLP LLC. Bacteria grown on nutrient media during sowing of the studied samples were studied and identified, as well as histological sections of the colon of experimental animals were analyzed. The research results demonstrate that the gut microbiota plays an important role in malignant neoplasms and has a potential antitumor effect, which makes it a promising object for further research in oncology. The following databases were used to perform the literature review: eLibrary.RU, Elsevier ScienceDirect, Scopus, PubMed. Statistical processing of experimental data was carried out using Microsoft Excel software.