cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Self-reported injury in Australian young adults: demographic and lifestyle predictors
Creators: name: MA Stokes
name: Hemphill, Sheryl
name: J McGillivray
name: T Evans-Whipp
name: L Satyen
name: JW Toumbourou
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 The Authors Objectives: Injury is the major cause of mortality and morbidity among adolescents and young adults. This study examined the use of injury self-reports and various causes of injury among adolescents. Methods: A cohort recruited in 2002 as a representative sample of students from the State of Victoria in south-east Australia was followed and resurveyed in young adulthood in 2010 (mean age 21.0) and 2012 (mean age 23.1) with 75% of the target sample retained (N=2,154, 55.8% female). Results: Prior injuries were reported by 55.5% in 2010 and 54.6% in 2012, leaving 18% with continuing disability. Reported causes of injury in 2012 were sports (55.1%) and alcohol use (9.7%). Logistic regression revealed that injury in 2012 was predicted by rural school attendance in 2002 (Adjusted Odds Ratio [OR] 1.4 CI 1.1–1.7) and in 2010 by male gender (OR 2.2, CI 1.8–2.6), reported self-harm (OR 1.6 CI 1.1–2.2), and unemployment (OR 0.7, CI 0.5–1.0). Conclusions: Self-reported injury among young adults is reliably reported, and suggests the need to further examine gender, rural communities and self-harm, and indicates modifiable contributors to injury. Implications for public health: Modifiable contributors to injury prevention are revealed as work environment, sports participation and alcohol use.
AI is not the problem - thinking about outcomes
Creators: name: Hsing, Pen-Yuan
name: Ding, Jennifer
Publisher: name: Zenodo
Year: 2024
Subjects: open science
open source
artificial intelligence
AI
open AI
open source AI

description: Talk given at the AESIS Open Science & Societal Impact conference 2024.

Key takeaways: 

Words matter, having clear definitions for terms like "AI" and "open source AI" is necessary but insufficient; 

We should adopt an outcomes-based approach to thinking about AI issues; 

With the understanding that AI is (very often) not the problem.

In addition to the slides and video recording here, the transcript, additional resources, and notes are published here: 

https://write.as/naclscrg/talk-ai-is-not-the-problem

The video recording can also be viewed on the Internet Archive: 

https://archive.org/details/AI-is-not-the-problem-2024-04-25
description: The open source font Metropolis is embedded in the attached presentation slides, which are saved with Microsoft® PowerPoint® LTSC 2021 (version 2108 build 16.0.14332.20678) in the OOXML Strict format (file extension .pptx). Users of other presentation software may need to install this font in their system before opening and remixing this presentation. The transcript for each slide is in the presenter notes.

The video recording (file extension `.mkv`) is encoded in H264 (video) and AAC (audio) and can be viewed in a video player such as the open source VLC. Video subtitles are separately saved in the SRT file, generated with the open source Whisper.cpp tool and its open-ish `medium.en` model. These generated subtitles have typos which are corrected in the transcript linked to above.
CRISPR-based Assay Reveals SARS-CoV-2 RNA Dynamic Changes and Redistribution Patterns in Non-Human Primate Model
Creators: name: Huang, Zhen
name: Zhang, Lili
name: Lyon, Christopher J.
name: Ning, Bo
name: Youngquist, Brady M.
name: Niu, Alex
name: Beddingfield, Brandon J.
name: Maness, Nicholas J.
name: Saba, Nakhle S.
name: Li, Chen-Zhong
name: Roy, Chad J.
name: Hu, Tony Y.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Mounting evidence indicates that SARS-CoV-2 can infect multiple systemic tissues, but few studies have evaluated SARS-CoV-2 RNA dynamics in multiple specimen types due to their reduced accessibility and diminished performance of RT-qPCR with non-respiratory specimens. Here, we employed an ultrasensitive CRISPR-RT-PCR assay to analyze longitudinal mucosal (nasal, buccal, pharyngeal, and rectal), plasma, and breath samples from SARS-CoV-2-infected non-human primates (NHPs) to detect dynamic changes in SARS-CoV-2 RNA level and distribution among these specimens. We observed that CRISPR-RT-PCR results consistently detected SARS-CoV-2 RNA in all sample types at most time points post-infection, and that SARS-CoV-2 infection dose and administration route did not markedly affect the CRISPR-RT-PCR signal detected in most specimen types. However, consistent RT-qPCR positive results were restricted to nasal, pharyngeal, and rectal swab samples, and tended to decrease earlier than CRISPR-RT-PCR results, reflecting lower assay sensitivity. SARS-CoV-2 RNA was detectable in both pulmonary and extrapulmonary specimens from early to late infection by CRISPR-RT-PCR, albeit with different abundance and kinetics, with SARS-CoV-2 RNA increases detected in plasma and rectal samples trailing those detected in upper respiratory tract samples. CRISPR-RT-PCR assays for SARS-CoV-2 RNA in non-respiratory specimens may thus permit direct diagnosis of suspected COVID-19 cases missed by RT-PCR, while tracking SARS-CoV-2 RNA in minimally invasive alternate specimens may better evaluate the progression and resolution of SARS-CoV-2 infections.
Usutu virus escapes langerin-induced restriction to productively infect human Langerhans cells, unlike West Nile virus
Creators: name: Martin, Marie-France
name: Maarifi, Ghizlane
name: Abiven, Hervé
name: Seffals, Marine
name: Mouchet, Nicolas
name: Beck, Cécile
name: Bodet, Charles
name: Lévèque, Nicolas
name: Arhel, Nathalie J.
name: Blanchet, Fabien P.
name: Simonin, Yannick
name: Nisole, Sébastien
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Usutu virus (USUV) and West Nile virus (WNV) are phylogenetically close emerging arboviruses transmitted by mosquitoes, and constitute a global public health threat. Since USUV and WNV enter the body through the skin, the first immune cells they encounter are skin-resident dendritic cells, the most peripheral outpost of immune defense. This unique network is composed of Langerhans cells (LCs) and dermal DCs, which reside in the epidermis and the dermis, respectively. Using human skin explants, we show that while both viruses can replicate in keratinocytes, they can also infect resident DCs with distinct tropism, since WNV preferentially infects DCs in the dermis, whereas USUV has a greater propensity to infect LCs. Using both purified human epidermal LCs (eLCs) and monocyte derived LCs (MoLCs), we confirm that LCs sustain a faster and more efficient replication of USUV compared with WNV and that this correlates with a more intense innate immune response to USUV compared with WNV. Next, we show that ectopic expression of the LC-specific C-type lectin receptor (CLR), langerin, in HEK293T cells allows WNV and USUV to bind and enter, but supports the subsequent replication of USUV only. Conversely, blocking or silencing langerin in MoLCs or eLCs made them resistant to USUV infection, thus demonstrating that USUV uses langerin to enter and replicate in LCs. Altogether, our results demonstrate that LCs constitute privileged target cells for USUV in human skin, because langerin favors its entry and replication. Intriguingly, this suggests that USUV efficiently escapes the antiviral functions of langerin, which normally safeguards LCs from most viral infections.
How museum specimens and community science data are used to revise the conservation status of a rattlesnake in Utah, USA.
Creators: name: Dittmer, Drew
Publisher: name: Zenodo
Year: 2022

description: Abstract of conference oral presentation on How museum specimens and community science data are used to revise the conservation status of a rattlesnake in Utah, USA. by Herpetologist Drew Dittmer of Herpetologist Utah Salt Lake City United States for SPNHC2022 Conference, Edinburgh. June 5-10th 2022.
Additional file 2 of Genetic dissection of 26 meat cut, meat quality and carcass traits in four pig populations
Creators: name: Xie, Lei
name: Qin, Jiangtao
name: Yao, Tianxiong
name: Tang, Xi
name: Cui, Dengshuai
name: Chen, Liqing
name: Rao, Lin
name: Xiao, Shijun
name: Zhang, Zhiyan
name: Huang, Lusheng
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Figure S1. Q-Q plot and lambda values of genome-wide association study (GWAS) of meat cut traits and carcass traits. Lambda values are normally used to characterize population stratification in multibreed GWAS.
AI is not the problem - thinking about outcomes
Creators: name: Hsing, Pen-Yuan
name: Ding, Jennifer
Publisher: name: Zenodo
Year: 2024
Subjects: open science
open source
artificial intelligence
AI
open AI
open source AI
reproducibility

description: Talk given at the AESIS Open Science & Societal Impact conference 2024 (in file `Hsing Open Science and Societal Impact talk 2024-04-25.pptx`). This was followed by a tweaked version that relates it to reproducibility at the Reproducibility by Design symposium at the University of Bristol on 26 June 2024 (in file `Hsing reproducibility symposium talk 2024-06-26.pptx`). 

Key takeaways: 

Words matter, having clear definitions for terms like "AI" and "open source AI" is necessary but insufficient; 

We should adopt an outcomes-based approach to thinking about AI issues; 

With the understanding that AI is (very often) not the problem.

In addition to the slides and video recording here, the list of references, transcript, additional resources, and notes are published here: 

https://write.as/naclscrg/talk-ai-is-not-the-problem

The video recording of the April 2024 talk can also be viewed on the Internet Archive: 

https://archive.org/details/AI-is-not-the-problem-2024-04-25
description: The open source font Metropolis is embedded in the attached presentation slides, which are saved with Microsoft® PowerPoint® LTSC 2021 (version 2108 build 16.0.14332.20678) in the OOXML Strict format (file extension .pptx). Users of other presentation software may need to install this font in their system before opening and remixing this presentation. The transcript for each slide is in the presenter notes.

The video recording (file extension `.mkv`) is encoded in H264 (video) and AAC (audio) and can be viewed in a video player such as the open source VLC. Video subtitles are separately saved in the SRT file, generated with the open source Whisper.cpp tool and its open-ish `medium.en` model. These generated subtitles have typos which are corrected in the transcript linked to above.
Additional file 1 of Evaluation of a decided sample size in machine learning applications
Creators: name: Rajput, Daniyal
name: Wang, Wei-Jen
name: Chen, Chun-Chuan
Publisher: name: figshare
Year: 2024
Subjects: subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1. Supplementary Figure 1: Assessment of logistic regression classifier with different methods by using (a) arrhythmia dataset (b) sleep dataset.
Theoretical analysis and application of immobilized methanotrophs as typical adsorbent materials for adsorption/degradation of trichloroethylene
Creators: name: Zhilin, Xing
name: Yunchun, Shi
name: Fang, Gou
name: Shuo, Ai
name: Hao, Liu
name: Xihong, Ke
name: Chao, Peng
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Trichloroethylene (TCE) contamination presents a significant environmental challenge, necessitating efficient treatment solutions. This study aimed to develop an optimized immobilized bioreactor using methanotrophs for TCE degradation. Activated carbon fibres were identified as the optimal immobilization material, with an adsorption rate of 6–23 h – significantly faster than over 50 h for other materials – and the highest methane oxidation capacity of 0.970 mL·g−1·h−1. Adsorption kinetics indicated that activated carbon fibres followed a second-order kinetic model with a constant of 0.598 g·mg−1·h−1, suitable for low-concentration bacterial solutions. Thermodynamic analysis confirmed an exothermic process, favouring lower temperatures (288.15 K). The negative interaction energies, as per DLVO theory, suggested electrostatic attraction as a key mechanism. The bioreactor achieved 99% TCE removal within 1 h at an initial concentration of 10 mg·L−1, with visible microbial immobilization within 5 days. This research provides a novel and effective approach for using immobilized methane-oxidizing bacteria in TCE treatment, offering both theoretical and practical advancements for chlorinated hydrocarbon wastewater management.
Lived experience and attitudes of people with plantar heel pain: a qualitative exploration
Creators: name: Cotchett, Matthew
name: Rathleff, Michael Skovdal
name: Dilnot, Matthew
name: Landorf, Karl
name: Morrissey, Dylan
name: Barton, Christian
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Background: Plantar heel pain is a common source of pain and disability. Evidence-based treatment decisions for people with plantar heel pain should be guided by the best available evidence, expert clinical reasoning, and consider the needs of the patient. Education is a key component of care for any patient and needs to be tailored to the patient and their condition. However, no previous work has identified, far less evaluated, the approaches and content required for optimal education for people with plantar heel pain. The aim of this study was to gather the patients' perspective regarding their lived experience, attitudes and educational needs in order to inform the content and provision of meaningful education delivery approaches. Methods: Using a qualitative descriptive design, semi-structured interviews were conducted with participants with a clinical diagnosis of plantar heel pain. A topic guide was utilised that focused on the experience of living with plantar heel pain and attitudes regarding treatment and educational needs. Interviews were audio recorded, transcribed verbatim and analysed using the Framework approach. Each transcription, and the initial findings, were reported back to participants to invite respondent validation. Results: Eighteen people with plantar heel pain were interviewed. Descriptive analysis revealed eight themes including perceptions of plantar heel pain, impact on self, dealing with plantar heel pain, source of information, patient needs, patient unmet needs, advice to others and interest in online education. Participants revealed doubt about the cause, treatment and prognosis of plantar heel pain. They also expressed a desire to have their pain eliminated and education individually tailored to their condition and needs. Respondent validation revealed that the transcripts were accurate, and participants were able to recognise their own experiences in the synthesised themes. Conclusion: Plantar heel pain has a negative impact on health-related quality of life. Participants wanted their pain eliminated and reported that their expectations and needs were frequently unmet. Health professionals have an important role to be responsive to the needs of the patient to improve their knowledge and influence pain and behaviour. Our study informs the content needed to help educate people with plantar heel pain.
Experimental study on enrichment of heavy metals by modified mullite during co-combustion of lignite with eucalyptus wood
Creators: name: Li, Jingjing
name: Yu, Zhaosheng
name: Dong, Jinxi
name: You, Zi
name: Teng, Wen
name: Ma, Xiaoqian
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Modifying the content of oxygen vacancies (OVs) has emerged as a crucial approach to tailoring silicate's adsorption properties, microstructure, conductivity, and catalytic performance. Some studies have reported the formation of OVs during ammonia treatment. However, there are limited studies on the production of OV-enriched mullite by treating it with N-containing compounds at low temperatures. In this work, formamide, urea, and ammonium acetate were used as ammonia-assisted reduction modifiers to induce oxygen vacancies in mullite at 30 ℃, 60 ℃, and 90 °C. The aim was to enhance the enrichment effect of heavy metals (Cr, Cu, Mn, Ni, Pb, Zn) during the co-combustion of coal and biomass. The modified mullite was analyzed by using X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET) surface area analysis, scanning electron microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR). The results indicated that the particle size of mullite decreased, and the concentration of internal Al3+ ions and oxygen vacancies was enhanced. Coal-biomass-mullite combustion experiments were conducted in a tubular furnace at 900 °C, revealing a significant enhancement in the enrichment of heavy metals during the combustion process, particularly when the modification temperature was 60 °C using ammonium acetate as the modifier. This work holds significant importance for developing novel heavy metal adsorbents and the reduction of pollutant emissions from coal-biomass co-combustion in industrial applications.
Additional file 3 of Genetic dissection of 26 meat cut, meat quality and carcass traits in four pig populations
Creators: name: Xie, Lei
name: Qin, Jiangtao
name: Yao, Tianxiong
name: Tang, Xi
name: Cui, Dengshuai
name: Chen, Liqing
name: Rao, Lin
name: Xiao, Shijun
name: Zhang, Zhiyan
name: Huang, Lusheng
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3: Figure S2. Genome-wide association study (GWAS) for thoracic number and thoracic length. a, b The Manhattan plots show the associations of 40,016 SNPs with thoracic number and thoracic length, respectively, in the combined population. c A haplotype view of all polymorphic sites within the 500-kb interval before and after the top significant SNP (rs0702038).
STRUCTURE  OF (2E,2'E)-3,3'-(1,3-PHENYLENE)BIS(1-(ANTHRACEN-9-YL)PROP-2-EN-1-ONE): A CHALCONE DERIVATIVE
Creators: name: Kant, Rajni
name: Sharma, Ratika
name: Salian, Vinutha V
name: Sarojini, B. K.
name: Narayana, B.
Publisher: name: European Chemical Bulletin
Year: 2015

description: The title compound C40H26O2 [(2E, 2'E)-3, 3'-(1,3-Phenylene)-bis(1-(anthracen-9-yl)prop-2-en-1-one)] was prepared from the reaction of  isophthalaldehyde and 9-acetylanthracene treated with solution of ethanol and sodium hydroxide.  It has been crystallized from DMF using slow evaporation method in the triclinic space group P-1 with Z=2 and unit cell parameters, a = 9.8276(8) b = 10.7470(8), c = 14.5606(10) Å, α= 99.833(6), β=104.495(6) & ϒ= 97.371(6)º. The architecture of the crystal structure is determined mainly by three intermolecular interactions [C23-H10…O1, C25-H15…O1, C16-H17…O1],  here O1 acts as an acceptor to three different carbon atoms, resulting into the formation of a  trifurcated hydrogen bond, forming a graph set motif R22(8) through a pair of C25-H15...O1 interactions.  These motifs are further extended through another intermolecular hydrogen bond [C3-H6...O2] forming a ladder like network, extending along the c-axis.
description: European Chemical Bulletin, Vol 4, No 7-9 (2015): European Chemical Bulletin
Immune modulation by design: Using topography to control human monocyte attachment and macrophage diﬀerentiation
Creators: name: Winkler, David
name: Vassey, Matt
name: D Scurr
name: Grazziela Figueredo
name: MR Alexander
name: S Vermeulen
name: AS Vasilevich
name: Boer, Jan De
name: Carlier, Aurelie
name: N Beijers
name: Ghaemmaghami, Amir
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Macrophages play a central role in orchestrating immune responses to foreign materials, which are often responsible for the failure of implanted medical devices. Material topography is known to influence macrophage attachment and phenotype, providing opportunities for the rational design of “immune-instructive” topographies to modulate macrophage function and thus foreign body responses to biomaterials. However, no generalizable understanding of the inter-relationship between topography and cell response exists. A high throughput screening approach is therefore utilized to investigate the relationship between topography and human monocyte–derived macrophage attachment and phenotype, using a diverse library of 2176 micropatterns generated by an algorithm. This reveals that micropillars 5–10 µm in diameter play a dominant role in driving macrophage attachment compared to the many other topographies screened, an observation that aligns with studies of the interaction of macrophages with particles. Combining the pillar size with the micropillar density is found to be key in modulation of cell phenotype from pro to anti-inflammatory states. Machine learning is used to successfully build a model that correlates cell attachment and phenotype with a selection of descriptors, illustrating that materials can potentially be designed to modulate inflammatory responses for future applications in the fight against foreign body rejection of medical devices.
An Additional Possibility of Using The Hill Coefficients
Creators: name: Krupyanko, V. I.
Publisher: name: European Chemical Bulletin
Year: 2015

description: The possibility of using the Hill coefficients is considered to estimate the strength of binding of substrates () with the first  () and also the second (K0(0.5) A) active center of two-subunit enzymes. The examples of how to calculate  and  constants are given.
description: European Chemical Bulletin, Vol 4, No 7-9 (2015): European Chemical Bulletin
Analysis of the regulation mechanism for salt-tolerant anammox process: process performance and metabolic insights
Creators: name: Zhang, Li
name: Liu, Kaishu
name: Huang, Diannan
name: Gao, Yunan
name: Li, Jiaxin
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Abstract: In this study, the start-up and microbial domestication of a salt-tolerant functional anammox system was investigated by gradually increasing the salinity level in a stabilized anammox system in the laboratory. After 44 days of stable operation, the salt-tolerant system was successfully activated, at which time the salinity of the influent water was 3 g/L, and the maximum removal efficiency of ammonia nitrogen and nitrite nitrogen in the system reached 94.18% and 96.66%, respectively, and then the ammonia nitrogen and nitrite nitrogen removal efficiency were stabilized at 88.17% and 96.48% after the enrichment domestication for 89 days. The system was operated in the salinity of 10 g/L, with the concentration of each nitrogen compound measured at the same time. The ammonia nitrogen removal efficiency decreased to 59.93% at a salinity of 10 g/L, which had a significant impact on the system. High-throughput sequencing revealed that the system was enriched with a large number of Chloroflexi, the relative abundance of which increased from 19.46% to 52.33%, and the genus of AnAOB was transformed from Candidatus Brocadia to Candidatus Kuenenia, Candidatus Kuenenia, with a percentage of 4.78%. The system successfully achieved the simultaneous removal of ammonia nitrogen and nitrite nitrogen under salinity stress, which to a certain extent indicated that AnAOB could achieve the initiation and enrichment domestication under salinity conditions, and could provide a basis for the efficient and low-consumption treatment of high salinity nitrogen-containing wastewater. HighlightsAnammox reaction can be successfully initiated under low salinity conditionsSalinity of 10 g/L has a severe shock effect on the anammox systemAfter salinity enrichment and domestication, the abundance of norank_f__norank__o___SBR1031 and Candidatus Kuenenia in the anammox reaction reached 26.7% and 4.78%, respectively Anammox reaction can be successfully initiated under low salinity conditions Salinity of 10 g/L has a severe shock effect on the anammox system After salinity enrichment and domestication, the abundance of norank_f__norank__o___SBR1031 and Candidatus Kuenenia in the anammox reaction reached 26.7% and 4.78%, respectively
Immune-Instructive Polymers Control Macrophage Phenotype and Modulate the Foreign Body Response In Vivo
Creators: name: Winkler, David
name: HM Rostam
name: LE Fisher
name: Hook, Andrew L
name: Burroughs, Laurence
name: JC Luckett
name: C Mbadugha
name: ACK Teo
name: A Latif
name: L Kämmerling
name: Barrett, Dave
name: S Elsheikh
name: Grazziela P Figueredo
name: M Ilyas
name: Alexander, Morgan R
name: Ghaemmaghami, Amir M
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 The Authors This study explores the hypothesis that simple polymer chemistries can be used to modulate the phenotype of human immune cells. Unbiased high-throughput screening of a large library of polymer chemistries is undertaken, identifying materials able to instruct macrophage attachment and polarization to pro- or anti-inflammatory phenotypes. The bioinstructive polymer function is validated by a murine model in which modulation of the foreign body response is shown. Polymer structure-cell response relationships modeled using machine learning reveal molecular descriptors useful for interpreting the immune-instructive polymers, highlighting the potential to undertake “immune-instructive” rational design. Identifying new polymers with immune-modulatory properties and elucidating the molecular mechanisms involved offer exciting possibilities to create novel bioinstructive materials with numerous clinical applications from implants and vaccine adjuvants to regenerative medicine and drug delivery.
CLOUD POINT EXTRACTION, PRECONCENTRATION, SPECTROPHTOMETRIC, DETERMINATION OF MAGNESIUM (II) BY USING 2,4-DIMETHYL-PENTAN-3-ONE
Creators: name: Jawada, Shawket K.
name: Hayder, Faris Hameed
Publisher: name: European Chemical Bulletin
Year: 2015

description: The cloud point extraction (CPE) method has been applied to the extraction and pre-concentration of Mg2+ ions. The extracted solvated species showed a maximum absorbance at λmax = 249 nm. The optimum conditions for extraction of solvated species to CPL are the presence of 0.5 M KNO3 for 50 µg Mg2+ ion in 10 ml aqueous solution with 1×10-4  M of extractant, 2,4-dimethyl-pentan-3-one (2,4-DMP) and heating up to 90 °C for 15 minutes and addition of 0.5 mL of 1 % Triton X–100 as surfactant. The study showed that different extractant have different extraction efficiency, acetophenone showing higher extraction efficiency but ethyl methyl ketone has a lower efficiency. The effect of different salts and variable concentration of nitrate salts on the extraction efficienct has been studied. Determination of Mg2+ in different samples has been studied with a RSD = 0.0074, DL = 1.84×10-5 and Sandel’s sensitivity = 3.58 ×10-9 μg cm-2.
description: European Chemical Bulletin, Vol 4, No 7-9 (2015): European Chemical Bulletin
ASAP3: Status update and activities for XFEL. From PETRA III to XFEL - Online & Offline Storage System based on Common Grounds
Creators: name: Dietrich, Stefan
name: Gasthuber, Martin
name: Kuhn, Manuela
name: Malka, Janusz
name: Ensslin, Uwe
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2016

description: HEPiX Spring 2016 Workshop, Zeuthen, DESY Zeuthen, Germany, 18 Apr 2016 - 22 Apr 2016
description: Since April 2015 we have been running our new storage infrastructure based on GPFS for the data acquisition and analysis of PETRA III.This presentation will show the current state of ASAP3, experiences from the first run period in production and current activities for XFEL.
Mardonios, Smaragdos, Mygdonios, Hilaros, Eugenios, Maximos, Petros, Dorotheos and Domna, martyrs at Nicomedia
Creators: name: Admin, CSLA
Publisher: name: University of Oxford
Year: 2016
Subjects: History

description: All evidence related to Mardonios, Smaragdos, Mygdonios, Hilaros, Eugenios, Maximos, Petros, Dorotheos and Domna, martyrs at Nicomedia.
How to CT scan "the gorilla in the room" without going ape
Creators: name: Watkins-Colwell, Gregory
Publisher: name: Zenodo
Year: 2022

description: Abstract of conference oral presentation on How to CT scan "the gorilla in the room" without going ape by Sr. Collection Manager - Ichthyology & Herpetology Gregory Watkins-Colwell of Sr. Collection Manager - Ichthyology & Herpetology Yale Peabody Museum Of Natural History New Haven United States for SPNHC2022 Conference, Edinburgh. June 5-10th 2022.
Efficient sulfur accumulation in biological desulfurisation and denitrification induced by microbial and chemical interactions
Creators: name: Xu, Jinlan
name: Cao, Fen
name: He, Chen
name: Dai, Jianan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Efficient accumulation of sulfur from simultaneous desulfurisation denitrification process can achieve high economic and environmental benefits. This work aims to study the effect of product accumulation on elemental sulfur production and understand its potential mechanism. The addition of the intermediate product thiosulfate and the final product sulfate during the reaction led to an increase in the production of biological elemental sulfur (Sbio0). The effect is mainly reflected in the efficient accumulation effect of Sbio0 at high sulfide loads. When the sulfide feed water load was 300 mg/L, the Sbio0 production reached 65.94 mg/L in 24 h with the addition of 30 mg/L thiosulfate and 20 mg/L sulfate, which was 3.11 times higher than that of the control group. The addition of sulfate increased the content of aromatic protein I and aromatic protein II, and accelerated the propagation of Thiobacillus denitrificans, whose viable bacterial amount was 1.12–2.98 times higher than that of the control group. On the one hand, low-dose sulfate induced Thiobacillus denitrificans to participate in the sulfur-producing reaction (S2−→Sbio0) more quickly by accelerating the propagation of the strains in the pre-reaction stage. On the other hand, the addition of sulfate shifted the overall reaction equilibrium to the left and inhibited the formation of thiosulfate, thus accelerating the accumulation of Sbio0 in the whole reaction stage. This study would provide guidance for artificially promoting efficient sulfur accumulation in desulfurisation denitrification treatments. HighlightsThe Sbio0 production reached 65.94 mg/L in 24 h at high sulfide load.20 mg/L sulfate induced the rapid propagation of Thiobacillus denitrificans.Thiobacillus denitrificans were involved early in the sulfur-producing reaction.Inhibition of thiosulfate formation indirectly promoted sulfur accumulation. The Sbio0 production reached 65.94 mg/L in 24 h at high sulfide load. 20 mg/L sulfate induced the rapid propagation of Thiobacillus denitrificans. Thiobacillus denitrificans were involved early in the sulfur-producing reaction. Inhibition of thiosulfate formation indirectly promoted sulfur accumulation.
$\alpha_s$ from hadron multiplicities via SUSY-like relation between anomalous dimensions
Creators: name: Kniehl, Bernd A.
name: Kotikov, Anatoly
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2017
Subjects: hadron: multiplicity
quark: flavor
quantum chromodynamics: supersymmetry
gluon: fragmentation function
evolution equation: solution
anomalous dimension
annihilation
strong coupling

description: We recover in QCD an amazingly simple relationship between the anomalous dimensions, resummed through next-to-next-to-leading-logarithmic order, in the Dokshitzer-Gribov-Lipatov-Altarelli-Parisi evolution equations for the first Mellin moments $D_{q,g}(\mu^2)$ of the quark and gluon fragmentation functions, which correspond to the average hadron multiplicities in jets initiated by quarks and gluons, respectively. This relationship, which is independent of the number of quark flavors, dramatically improves previous treatments by allowing for an exact solution of the evolution equations. So far, such relationships have only been known from supersymmetric QCD, where $C_F/C_A=1$. This also allows us to extend our knowledge of the ratio $D_g^-(\mu^2)/D_q^-(\mu^2)$ of the minus components by one order in $\sqrt{\alpha_s}$. Exploiting available next-to-next-to-next-to-leading-order information on the ratio $D_g^+(\mu^2)/D_q^+(\mu^2)$ of the dominant plus components, we fit the world data of $D_{q,g}(\mu^2)$ for charged hadrons measured in $e^+e^-$ annihilation to obtain $\alpha_s^{(5)}(M_Z)=0.1205\genfrac{}{}{0pt}{}{+0.016}{-0.0020}$.
A comparison of acute glycaemic responses to accumulated or single bout walking exercise in apparently healthy, insufficiently active adults
Creators: name: Shambrook, Philip
name: Kingsley, Michael
name: Taylor, Nicholas
name: Wundersitz, Daniel
name: Wundersitz, Claire E
name: Paton, Carl D
name: Gordon, Brett
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 Sports Medicine Australia Objectives: To investigate the acute glyacaemic response to accumulated or single bout walking exercise in apparently healthy adults. Design: Three arm, randomised crossover control study. Methods: Ten adults (age: 50 ± 12.6 y; BMI 29.0 ± 5.4 kg m−2) completed three separate trials comprising three 10-min walking bouts after breakfast, lunch, and dinner (APPW), a single 30-min walking bout after dinner only (CPPW), or a no-exercise control (NOEX). Participants walked on a treadmill at a moderate intensity of 55%–70% heart rate reserve. Two-hour postprandial glucose response was assessed using a continuous glucose monitor. Results: There was a difference in the pattern of the glucose response between the trials during the two hours following dinner (p < 0.001). Postprandial dinner glucose concentrations were not different between APPW and CPPW but were up to 1.01 mmol L−1 lower than NOEX (partial eta2 = 0.21, p = 0.041). Conclusions: Ten minutes of moderate intensity walking completed 30 min after each meal lowers postprandial dinner glucose concentrations in comparison to no-exercise, and reduces glucose by a similar magnitude as a single 30-min bout after the evening meal. Short bouts of exercise after each meal may be recommended to minimise glucose elevations after dinner that might increase risk of cardiometabolic disease.
Figure_A1 – Supplemental material for CEA and CYFRA 21-1 as prognostic biomarker and as a tool for treatment monitoring in advanced NSCLC treated with immune checkpoint inhibitors
Creators: name: Dall’Olio, Filippo G.
name: Abbati, Francesca
name: Facchinetti, Francesco
name: Massucci, Maria
name: Melotti, Barbara
name: Squadrilli, Anna
name: Buti, Sebastiano
name: Formica, Francesca
name: Tiseo, Marcello
name: Ardizzoni, Andrea
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 110203 Respiratory Diseases

description: Supplemental material, Figure_A1 for CEA and CYFRA 21-1 as prognostic biomarker and as a tool for treatment monitoring in advanced NSCLC treated with immune checkpoint inhibitors by Filippo G. Dall’Olio, Francesca Abbati, Francesco Facchinetti, Maria Massucci, Barbara Melotti, Anna Squadrilli, Sebastiano Buti, Francesca Formica, Marcello Tiseo and Andrea Ardizzoni in Therapeutic Advances in Medical Oncology
The relationship between lifestyle and serum neurofilament light protein in Huntington’s disease
Creators: name: T Cruickshank
name: D Bartlett
name: Govus, Andrew
name: A Hannan
name: WP Teo
name: S Mason
name: J Lo
name: M Ziman
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 The Authors. Brain and Behavior published by Wiley Periodicals, Inc. Objectives: Serum neurofilament light protein (NfL) is a promising marker of disease onset and progression in Huntington's disease (HD). This study investigated associations between lifestyle factors and NfL levels in HD mutation carriers compared to healthy age- and sex-matched controls. Materials and Methods: Participants included 29 HD mutation carriers and 15 healthy controls. Associations between serum NfL concentrations and lifestyle factors, including cardiorespiratory fitness, social network size and diversity, physical activity, cognitive reserve, smoking status, and alcohol consumption, were examined using a stepwise multivariable linear regression model. Results: Higher NfL levels were associated with lower cognitive reserve, social network size and diversity and cardiorespiratory fitness in HD mutation carriers. Group × lifestyle factor effects were observed between lower serum NfL levels and a greater social network diversity. Conclusion: These findings highlight a relationship between lifestyle factors and NfL levels in HD mutations carriers; however, longitudinal studies are required to confirm if these observed relationships persist over time.
Dairy sludge characteristics and its degradation during thermal treatment and thermal plasma treatment
Creators: name: Júnior, Pedro William Paiva Moreira
name: de Souza Miranda, Felipe
name: Prado, Eduardo Sant Ana Petraconi
name: Essiptchouk, Alexei Mikhailovich
name: Cruz, Antônio Carlos
name: Filho, Gilberto Petraconi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Thermal treatment and thermal plasma treatment processes of dairy sludge were conducted. The thermal treatment was undertaken at temperatures from 200 °C to 1000 °C to establish the chemical composition and thermal degradation of the sludge. These results served as a foundation for interpreting the properties of the vitreous slag obtained from the sludge treated in the DC-transferred arc plasma reactor. The dairy sludge is characterised by a high volatile matter but also presents substantial ash content, with primary elements such as Al, P, Si, Ca, and Fe. The characterisations of the samples were made employing techniques like X-ray fluorescence, X-ray diffraction analysis (XRD), FT-IR spectrometry, Thermogravimetric analysis, and Differential Scanning Calorimetry. The results highlight the degradation of primary milk components like lactose, casein protein, and milk fat, with distinct differential thermogravimetric peaks at 230, 316, and 479 °C. As the temperature of thermal treatments approached 1000°C, silicon dioxide, calcium silicon, dicalcium silicate, and hydroxyapatite were identified in XRD spectra. Plasma-treated sludge features various oxide crystalline structures, including Al2O3, CaO(Al2O3)6, CaO(Al2O3)2, Ca2Al(AlSi)O7, KFeO2, and ZrO1.98. FTIR analysis of sludge identifies a complex organic composition presenting alkanes, amines, amides, hydroxyl groups, and metallic and semi-metallic oxide bond absorption. The FTIR results suggest the degradation of organic compounds and retention of phosphorous and aluminum bonds, especially after 600 °C. The vitreous slag from plasma treatment exhibits distinct composition characteristics without organic compound, presenting a vitreous and metallic/ceramic matrix. This research underscores the potential of thermal plasma treatments to neutralise dairy sludge.
How to make a low-quality mount useful. Increasing the institutional value of taxidermy mounts by balancing object conservation ideals and economy in mount restoration and modification.
Creators: name: Sullivan, Steven
Publisher: name: Zenodo
Year: 2022

description: Abstract of conference oral presentation on How to make a low-quality mount useful. Increasing the institutional value of taxidermy mounts by balancing object conservation ideals and economy in mount restoration and modification. by Steven Sullivan of Hefner Museum of Natural History, Miami University Oxford, Ohio United States for SPNHC2022 Conference, Edinburgh. June 5-10th 2022.
Loss of trace elements from agricultural soil
Creators: name: Comber, S. D. W.
name: Schindler, R. J.
name: Blackwell, M. S. A.
name: Darch, T.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Computational Biology

description: Soil erosion is a world-wide issue driven by land management and climate change. Research has focussed on soil loss rates from agricultural land. However, the loss of trace elements essential for soil and plant health, or potentially toxic elements that occur as impurities in fertilisers and manures, is poorly understood. This study reports on the loads and forms of copper, cadmium, manganese, nickel, selenium and zinc lost from three types of agricultural systems at Rothamsted Research’s North Wyke Farm Platform over five individual storm events. Loads reflected a combination of concentrations in the soil, annual additions from fertilisers, the ability to leach from the soil and rainfall intensity. Arable fields demonstrated an order of magnitude greater loss of soil compared to pasture. Consequently, particulate-bound losses were higher, and the proportion of losses in solution were 29% lower on average, compared with pasture. Overall losses for each element were statistically similar for pastures. In comparison, arable fields showed greater average losses for five essential elements (15.3%) compared to pasture (9.7%). Nickel exhibited the greatest average loss (27% overall; 39% for arable) and zinc the lowest (2% overall; 3% for arable). The predominant loss of cadmium was in the dissolved phase (96% overall; 92% arable), followed by selenium (81%/63%), nickel (64%/35%) and copper (61%/34%). Conversely, dissolved losses of manganese (38%/21%) and zinc (28%/8%) were lower than particulate losses. We conclude that overall loss, and form of the loss, varies significantly between arable and pastoral systems, and the physico-chemical properties of the element itself. HighlightsSoil loss from arable land is up to 10 times that of pasture.Trace elements are strongly associated with sediment in runoff from arable fields.Dissolved trace element concentration is relatively stable across a rain event.Relative losses of dissolved versus particulate-bound metals varied between elements. Up to 40% of nickel applied to soil is leached. Soil loss from arable land is up to 10 times that of pasture. Trace elements are strongly associated with sediment in runoff from arable fields. Dissolved trace element concentration is relatively stable across a rain event. Relative losses of dissolved versus particulate-bound metals varied between elements. Up to 40% of nickel applied to soil is leached.
Local population density affects pollinator visitation in the endangered grassland daisy Rutidosis leptorhynchoides (Asteraceae)
Creators: name: B Courtice
name: Hoebee, Susan
name: S Sinclair
name: Morgan, John
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2019 CSIRO. The spatial arrangement of plants has implications for their pollination. Dense patches of flowering plants can result in increased pollinator attraction and, consequently, higher pollination and seed set per flower. We investigated this effect in the endangered, self-incompatible Australian daisy Rutidosis leptorhynchoides F.Muell. (Asteraceae) by quantifying the effect of plant density on pollinator visitation and seed set in a wild population. Pollinator activity was investigated by direct observation of insect behaviour, by examining the pollen carried on candidate insect species, by video monitoring of visitation, and by tracking the movement of dye as a pollen analogue. Two native Lasioglossum species (Hymenoptera: Halictidae) were identified as the most frequent pollen-carrying visitors to inflorescences. Their visitation was significantly higher where plants were dense, but no statistical correlation between seed set and plant density was found. Florivory was identified as potentially having a substantial negative influence on seed set, but without any clear relationship to plant density. Given that R. leptorhynchoides has declined substantially across its range, and previous reintroduction attempts have often failed, our findings provide key information pertaining to knowledge of pollinator and florivore behaviour in relation to plant density. To maximise success of future management strategies, these animal-plant interactions should be captured in species recovery designs.
Additional file 1 of Pediatric outdoor recreational injuries: another hidden concern during the COVID-19 pandemic
Creators: name: Blumberg, Melissa P.
name: Gittelman, Michael A.
name: Pomerantz, Wendy J.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Additional file 1. Included ICD-10 Codes