cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Effects of Species Abundance, Spatial Distribution, and Phylogeny on a Plant-Ectomycorrhizal Fungal Network
Creators: name: Zhu, C
name: Wang, Z
name: Deane, David
name: Luo, W
name: Chen, Y
name: Cao, Y
name: Lin, Y
name: Zhang, M
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 3004
subject: Crop and pasture production
classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3103
subject: Ecology
classificationCode: 3107
subject: Microbiology
classificationCode: 3108
subject: Plant biology

description: Plant and root fungal interactions are among the most important belowground ecological interactions, however, the mechanisms underlying pairwise interactions and network patterns of rhizosphere fungi and host plants remain unknown. We tested whether neutral process or spatial constraints individually or jointly best explained quantitative plant–ectomycorrhizal fungal network assembly in a subtropical forest in southern China. Results showed that the observed plant–ectomycorrhizal fungal network had low connectivity, high interaction evenness, and an intermediate level of specialization, with nestedness and modularity both greater than random expectation. Incorporating information on the relative abundance and spatial overlap of plants and fungi well predicted network nestedness and connectance, but not necessarily explained other network metrics such as specificity. Spatial overlap better predicted pairwise species interactions of plants and ectomycorrhizal fungi than species abundance or a combination of species abundance and spatial overlap. There was a significant phylogenetic signal on species degree and interaction strength for ectomycorrhizal fungal but not for plant species. Our study suggests that neutral processes (species abundance matching) and niche/dispersal-related processes (implied by spatial overlap and phylogeny) jointly drive the shaping of a plant-ectomycorrhizal fungal network.
DS1_JVDI_10.1177_1040638718810744 – Supplemental material for Validation of an in-house real-time PCR fecal assay and comparison with two commercial assays for the antemortem detection of Mycobacterium avium subsp. paratuberculosis infection in culled sheep
Creators: name: Arsenault, Julie
name: Jagdip Singh Sohal
name: Leboeuf, Anne
name: Hélie, Pierre
name: Fecteau, Gilles
name: Robinson, Yves
name: L’Homme, Yvan
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, DS1_JVDI_10.1177_1040638718810744 for Validation of an in-house real-time PCR fecal assay and comparison with two commercial assays for the antemortem detection of Mycobacterium avium subsp. paratuberculosis infection in culled sheep by Julie Arsenault, Jagdip Singh Sohal, Anne Leboeuf, Pierre Hélie, Gilles Fecteau, Yves Robinson and Yvan L’Homme in Journal of Veterinary Diagnostic Investigation
Origin and Global Expansion of Mycobacterium tuberculosis Complex Lineage 3
Creators: name: Shuaib, YA
name: Utpatel, C
name: Kohl, TA
name: Barilar, I
name: Diricks, M
name: Ashraf, N
name: Wieler, LH
name: Kerubo, G
name: Mesfin, EA
name: Diallo, AB
name: Al-Hajoj, S
name: Ndung’u, P
name: Fitzgibbon, MM
name: Vaziri, F
name: Sintchenko, V
name: Martinez, E
name: Viegas, SO
name: Zhou, Y
name: Azmy, A
name: Al-Amry, K
name: Godreuil, S
name: Varma-Basil, M
name: Narang, A
name: Ali, S
name: Beckert, P
name: Dreyer, V
name: Kabwe, Mwila
name: Bates, M
name: Hoelscher, M
name: Rachow, A
name: Gori, A
name: Tekwu, EM
name: Sidze, LK
name: Jean-Paul, AA
name: Beng, VP
name: Ntoumi, F
name: Frank, M
name: Diallo, AG
name: Mboup, S
name: Tessema, B
name: Beyene, D
name: Khan, SN
name: Diel, R
name: Supply, P
name: Maurer, FP
name: Hoffmann, H
name: Niemann, S
name: Merker, M
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3105
subject: Genetics

description: Mycobacterium tuberculosis complex (MTBC) Lineage 3 (L3) strains are abundant in world regions with the highest tuberculosis burden. To investigate the population structure and the global diversity of this major lineage, we analyzed a dataset comprising 2682 L3 strains from 38 countries over 5 continents, by employing 24-loci mycobacterial interspersed repetitive unit-variable number of tandem repeats genotyping (MIRU-VNTR) and drug susceptibility testing. We further combined whole-genome sequencing (WGS) and phylogeographic analysis for 373 strains representing the global L3 genetic diversity. Ancestral state reconstruction confirmed that the origin of L3 strains is located in Southern Asia and further revealed multiple independent introduction events into North-East and East Africa. This study provides a systematic understanding of the global diversity of L3 strains and reports phylogenetic variations that could inform clinical trials which evaluate the effectivity of new drugs/regimens or vaccine candidates.
Supplementary_Material – Supplemental material for Quotas and Party Priorities: Direct and Indirect Effects of Quota Laws
Creators: name: Weeks, Ana Catalano
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, Supplementary_Material for Quotas and Party Priorities: Direct and Indirect Effects of Quota Laws by Ana Catalano Weeks in Political Research Quarterly
Miller_OnlineAppendix – Supplemental material for The Temporal Dimension of System Justification: Gender Ideology Over the Course of the 2016 Election
Creators: name: Miller, Andrea L.
name: Borgida, Eugene
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Miller_OnlineAppendix for The Temporal Dimension of System Justification: Gender Ideology Over the Course of the 2016 Election by Andrea L. Miller and Eugene Borgida in Personality and Social Psychology Bulletin
Calculating bond dissociation energies of X-H (X=C, N, O, S) bonds of aromatic systems via density functional theory: A detailed comparison of methods
Creators: name: Trung, NQ
name: Mechler, Adam
name: Hoa, NT
name: Vo, Quan Van
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences
classificationCode: 3406
subject: Physical chemistry
classificationCode: 3407
subject: Theoretical and computational chemistry

description: In this study, the performance of 17 different density functional theory functionals was compared for the calculation of the bond dissociation energy (BDE) values of X-H (X=C, N, O, S) bonds of aromatic compounds. The effect of the size of the basis set (expansions of 6-31(G)) was also assessed for the initial geometry and zero-point energy calculations, followed by the single-point BDE calculations with different model chemistries with the 6-311 + (3df,2p) basis set. It was found that the size of the basis set for geometry optimization has a much smaller effect on the accuracy of BDE than the choice of functional for the following single-point calculations. The M06-2X, M05-2X and M08-HX functionals yielded highly accurate BDE values compared to experimental data (with the average mean unsigned error MUE = 1.2-1.5 kcal mol-1), performing better than any of the other functionals. The results suggest that geometry optimization may be performed with B3LYP functional and a small basis set, whereas the M06-2X, M05-2X and M08-HX density functionals with a suitably large basis set offer the best method for calculating BDEs of ArX-H (X=C, N, O, S) bonds.
Supplemental Material, DS1_VET_10.1177_0300985818808530 - FoxP3 and IDO in Canine Melanocytic Tumors
Creators: name: Porcellato, Ilaria
name: Brachelente, Chiara
name: Paolis, Livia De
name: Menchetti, Laura
name: Silvestri, Serenella
name: Sforna, Monica
name: Vichi, Gaia
name: Iussich, Selina
name: Mechelli, Luca
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental Material, DS1_VET_10.1177_0300985818808530 for FoxP3 and IDO in Canine Melanocytic Tumors by Ilaria Porcellato, Chiara Brachelente, Livia De Paolis, Laura Menchetti, Serenella Silvestri, Monica Sforna, Gaia Vichi, Selina Iussich, and Luca Mechelli in Veterinary Pathology
Parenthood With Kidney Failure: Answering Questions Patients Ask About Pregnancy
Creators: name: Jesudason, S
name: Williamson, A
name: Huuskes, Brooke
name: Hewawasam, E
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3215
subject: Reproductive medicine
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: Achieving parenthood can be an important priority for women and men with kidney failure. In recent decades, the paradigm has shifted toward greater support of parenthood, with advances in our understanding of risks related to pregnancy and improvements in obstetrical and perinatal care. This review, codesigned by people with personal experience of kidney disease, provides guidance for nephrologists on how to answer the questions most asked by patients when planning for parenthood. We focus on important issues that arise in preconception counseling for women receiving dialysis and postkidney transplant. We summarize recent studies reflecting pregnancy outcomes in the modern era of nephrology, obstetrical, and perinatal care in developed countries. We present visual aids to help clinicians and women navigate pregnancy planning and risk assessment. Key principles of pregnancy management are outlined. Finally, we explore outcomes of fatherhood in males with kidney failure.
QJE-STD_17-202.R2-Supplementary_Material – Supplemental material for Age-related effects in compound production: Evidence from a double-object picture naming task
Creators: name: Lorenz, Antje
name: Pienie Zwitserlood
name: Regel, Stefanie
name: Rahman, Rasha Abdel
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, QJE-STD_17-202.R2-Supplementary_Material for Age-related effects in compound production: Evidence from a double-object picture naming task by Antje Lorenz, Pienie Zwitserlood, Stefanie Regel and Rasha Abdel Rahman in Quarterly Journal of Experimental Psychology
Exploring hot spots of short birth intervals and associated factors using a nationally representative survey in Bangladesh
Creators: name: Islam, MZ
name: Islam, Md
name: Rahman, MM
name: Khan, MN
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4206
subject: Public health
classificationCode: 44
subject: Human society

description: Short Birth Interval (SBI, defined as < 33 months interval between the two most recent births or < 24 months between one live birth to the next pregnancy) is a public health problem in most low- and lower-middle-income countries. Understanding geographic variations in SBI, particularly SBI hot spots and associated factors, may help intervene with tailored programs. This study identified the geographical hot spots of SBI in Bangladesh and the factors associated with them. We analyzed women’s data extracted from the 2017/18 Bangladesh Demographic and Health Survey and the healthcare facility data extracted from the 2017 Service Provision Assessment. SBI was the outcome variable, and it was defined as an interval between consecutive births of 33 months or less, as recommended by the World Health Organization. The characteristics of mothers and their partners were the explanatory variables. Moran’s I was used to examine the spatial variation of SBI in Bangladesh whereas the Getis-Ord Gi∗(d) was used to determine the hot spots of SBI. The Geographical Weighted Regression (GWR) was used to assess the predictors of SBI at the enumeration areas’ level. The variables included in the GWR were selected using the exploratory regression and ordinary least square regression model. Data of 5941 women were included in the analyses. Around 26% of the total births in Bangladesh had occurred in short intervals. A majority of the SBI hot spots were found in the Sylhet division, and almost all SBI cold spots were in the Rajshahi and Khulna divisions. No engagement with formal income-generating activities, high maternal parity, and history of experiencing the death of a child were significantly associated with SBI in the Sylhet division. Women’s age of 34 years or less at the first birth was a protective factor of SBI in the Rajshahi and Khulna divisions. The prevalence of SBI in Bangladesh is highly clustered in the Sylhet division. We recommend introducing tailored reproductive health care services in the hot spots instead of the existing uniform approach across the country.
Supplemental Material, DS1_VET_10.1177_0300985818806963 - Chlamydia pecorum Infection in the Male Reproductive System of Koalas (Phascolarctos cinereus)
Creators: name: Palmieri, Chiara
name: Lyndal Hulse
name: Pagliarani, Sara
name: Larkin, Rebecca
name: Higgins, Damien P.
name: Beagley, Kenneth
name: Johnston, Stephen
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental Material, DS1_VET_10.1177_0300985818806963 for Chlamydia pecorum Infection in the Male Reproductive System of Koalas (Phascolarctos cinereus) by Chiara Palmieri, Lyndal Hulse, Sara Pagliarani, Rebecca Larkin, Damien P. Higgins, Kenneth Beagley, and Stephen Johnston in Veterinary Pathology
Triglyceride-glucose index variability and incident cardiovascular disease: a prospective cohort study
Creators: name: Li, H
name: Zuo, Y
name: Qian, F
name: Chen, S
name: Tian, X
name: Wang, P
name: Li, Xia
name: Guo, X
name: Wu, S
name: Wang, A
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3201
subject: Cardiovascular medicine and haematology

description: Background: Recent studies have suggested that triglyceride-glucose (TyG) index is an independent predictor of cardiovascular disease (CVD). However, the impact of long-term visit-to-visit variability in TyG index on the risk of CVD is not known. We aimed to investigate the longitudinal association between baseline and mean TyG index as well as TyG index variability and incident CVD in a Chinese population. Methods: We included 49,579 participants without previous history of CVD in the Kailuan study who underwent three health examinations (2006, 2008, and 2010) and were followed up for clinical events until 2019. TyG index was calculated as Ln [fasting triglyceride (mg/dL) × fasting glucose (mg/dL)/2]. We measured TyG index variability as the SD of the residuals obtained from a linear regression on the three TyG index measurements for each individual. Multivariate-adjusted Cox models were used to estimate the adjusted hazard ratio (aHR) and 95% confidence interval (CI) with incident CVD. Results: During a median follow-up time of 9.0 years, 2404 developed CVD. The highest tertile (T3) of baseline and mean TyG index were each associated with higher CVD incidence as compared with the lowest tertile (T1): aHR, 1.25; 95% CI 1.11–1.42; and aHR 1.40; 95% CI 1.24–1.58, respectively. Tertile 3 of TyG index variability was associated with increased CVD incidence compared to T1 group (aHR, 1.12; 95% CI 1.01–1.24). Similar findings were observed in a series of sensitivity analyses. Conclusion: Higher TyG index level and greater TyGindex variability were each independently associated with a higher incidence of CVD.
The acquisition of clitic dative doubling in heritage speakers and L2 Spanish
Creators: name: Sr, Francisco Javier Clavijo
Publisher: name: Purdue University Graduate School
Year: 2024
Subjects: classificationCode: 470401
subject: Applied linguistics and educational linguistics

description: This study investigates the production of dative clitic doubling among Spanish heritage speakers and English-speaking L2 learners of Spanish. Dative clitic doubling, a grammatical structure in Spanish, is challenging for bilingual speakers (Montrul, 1998; Cuervo, 2007; Escobar-Alvarez, 2017). The study examines the extent to which heritage speakers of Spanish and L2 learners demonstrate knowledge of dative clitic doubling in Spanish with ditransitive verbs across four conditions: psych verbs, wh-questions, double object constructions, and inalienable possession. The results from an online Elicited Production Task reveal that L2 learners exhibit crosslinguistic influence from their L1, characterized by the omission of the dative clitic in the analyzed structures. Heritage speakers also show some degree of crosslinguistic influence, often preferring prepositional constructions over dative clitic doubling. The findings are discussed in the context of the current discourse on the roles of proficiency, language use, and exposure.
How have Cretan rivers responded to late Holocene uplift? A multi-millennial, multi-catchment field experiment to evaluate the applicability of Schumm and Parker's (1973) complex response model
Creators: name: Macklin, Mark
name: Booth, J
name: Brewer, PA
name: Tooth, S
name: Duller, GAT
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 37
subject: Earth sciences
classificationCode: 3705
subject: Geology
subject: FOS: Earth and related environmental sciences
classificationCode: 3707
subject: Hydrology
classificationCode: 3709
subject: Physical geography and environmental geoscience

description: ‘Complex response’ (Schumm, 1973, Geomorphic thresholds and complex response of drainage systems. In Morisawa, M. (ed.), Fluvial Geomorphology. Binghamton: New York State University Publications: 299-310) describes situations in which a single event triggers a series of progressively damped morphological and sedimentary adjustments within a catchment. Schumm and Parker's (1973, Implications of complex response of drainage systems for Quaternary alluvial stratigraphy. Nature 243: 99–100) classic stream table experiment of drainage system development showed that one baselevel fall event could result in formation of two sets of paired river terraces that need not be related to additional external (e.g., climate) influences. Despite its enduring popularity in fluvial geomorphology, large-scale and long-term field evaluations of Schumm and Parker's complex response model are very limited. Here, we report on a multi-millennial, multi-catchment field experiment in south-western Crete where a high-magnitude earthquake (estimated magnitude 8.3–8.5) on 21 July 365 ce resulted in up to 9 m of instantaneous uplift over a land area exceeding 6000 km2. Geomorphological, sedimentological, and chronological investigations were used to investigate the erosional and depositional histories in three catchments with outlets uplifted by the 365 ce event. These catchments were compared with the Anapodaris catchment in south central Crete where baselevel was not significantly affected by the earthquake. Although all uplifted catchments experienced valley floor incision, this occurred hundreds of years after 365 ce during a period of wetter climate. The number and age of trunk stream incision and aggradation phases are similar in both uplifted and non-uplifted catchments, indicating that river responses following the 365 ce uplift event have not followed complex response trajectories in the form documented by Schumm and Parker (1973). This finding highlights the need for rigorous evaluation of other catchment or river response concepts, including through the combined use of laboratory experimental results, field data, and geochronology. In an era of rapid environmental change, characterizing and anticipating catchment and river system response increasingly will depend on a healthy interplay between different investigative approaches.
Additional file 5 of Effects of Malate Ringer's solution on myocardial injury in sepsis and enforcement effects of TPP@PAMAM-MR
Creators: name: Tan, Lei
name: She, Han
name: Zheng, Jie
name: Peng, Xiaoyong
name: Guo, Ningke
name: Zhang, Bindan
name: Sun, Yue
name: Ma, Chunhua
name: Xu, Shenglian
name: Bao, Daiqin
name: Zhou, Yuanqun
name: Li, Qinghui
name: Mao, Qingxiang
name: Liu, Liangming
name: Hu, Yi
name: Li, Tao
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 5: Figure S5. (A) Liver injury scores (n = 3/group). (B) Kidney injury scores (n = 3/group). (C) Heart injury scores (n = 3/group).
Stand und Perspektive des Open-Access-Reportings
Creators: name: Barbers, Irene
name: Kindling, Maxi
name: Stadler, Heike
name: Strecker, Dorothea
Publisher: name: Forschungzentrum Jülich
Year: 2024

description: Open-Access-Tage 2024, OAT2024, Köln, Germany, 10 Sep 2024 - 12 Sep 2024; doi:10.5281/ZENODO.13831942
description: Vor dem Hintergrund der Definition expliziter Zielmarken für das Open-Access-Publikationsaufkommen durch das Bundesministerium für Bildung und Forschung, einiger Bundesländer und verschiedener weiterer Stakeholder gewinnt Open-Access-Reporting weiter an Bedeutung. Gleichzeitig erschweren Umstände wie die komplexe Datenlage eine flächendeckende Implementierung von Verfahren, und es wird deutlich, dass das Erfassen des Publikationsaufkommens durch die Betrachtung weiterer Indikatoren ergänzt werden sollte, um den unterschiedlichen Typen von Hochschulen und deren fachlicher Ausrichtung besser gerecht zu werden. Dieser interaktive Workshop wurde im Rahmen der Open-Access-Tage 2024 durchgeführt und richtete sich an Mitarbeitende an wissenschaftlichen Einrichtungen, die an der Durchführung von Open-Access-Reporting interessiert sind. Im Workshop wurden unterschiedliche Ansätze des Open-Access-Reportings beleuchtet und diskutiert sowie anhand praxisnaher Beispiele das konkrete Vorgehen bei der Berichterstattung vermittelt. Der Workshop wurde mit kurzen Praxisberichten zu Open-Access-Reporting auf Länderebene basierend auf qualitativen und quantitativen Ansätzen durch das Open-Access-Büro Berlin [1] und die Vernetzungs- und Kompetenzstelle Brandenburg [2] eröffnet. Anschließend erhielten Teilnehmende anhand eigener Fragestellungen und Analyseszenarien einen Einblick in die Nutzung des Open Access Monitors [3] für das Reporting des Publikationsaufkommens ihrer Einrichtung sowie ergänzender Informationen zu Strategien und Services von wissenschaftlichen Einrichtungen auf Basis des oa.atlas [4]. Anhand vom Projekt OA Datenpraxis [5] vorbereiteter Impulse diskutierten Teilnehmende in Kleingruppen Chancen und Herausforderungen der vorgestellten Reporting-Ansätze, bevor die Ergebnisse kurz im Plenum vorgestellt wurden. [1] https://www.open-access-berlin.de [2] https://open-access-brandenburg.de [3] open-access-monitor.de [4] open-access.network/services/oaatlas [5] https://oa-datenpraxis.de
Corrections to the Higgs-Boson spectrum in the complex MSSM
Creators: name: Paßehr, Sebastian
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2016

description: FeynHiggs workshop, Munich, DESY, Germany, 28 Nov 2016 - 30 Nov 2016 ; (2016).
Interrogating the intentions for Aboriginal and Torres Strait Islander health: a narrative review of research outputs since the introduction of Closing the Gap
Creators: name: Kennedy, M
name: Bennett, J
name: Maidment, S
name: Chamberlain, Catherine
name: Booth, K
name: McGuffog, R
name: Hobden, B
name: Whop, LJ
name: Bryant, J
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3202
subject: Clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems

description: Despite the “best of intentions”, Australia has fallen short of federal targets to close the gap in disproportionate health outcomes between Aboriginal and non-Aboriginal Australians. We examined 2150 original research articles published over the 12-year period (from 2008 to 2020), of which 58% used descriptive designs and only 2.6% were randomised controlled trials. There were few national studies. Studies were most commonly conducted in remote settings (28.8%) and focused on specific burdens of disease prevalent in remote areas, such as infectious disease, hearing and vision. Analytic observational designs were used more frequently when addressing burdens of disease, such as cancer and kidney and urinary, respiratory and endocrine diseases. The largest number of publications focused on mental and substance use disorders (n = 322, 20.5%); infectious diseases (n = 222, 14.1%); health services planning, delivery and improvement (n = 193, 33.5%); and health and wellbeing (n = 170, 29.5%). This review is timely given new investments in Aboriginal health, which highlights the importance of Aboriginal researchers, community leadership and research priority. We anticipate future outputs for Aboriginal health research to change significantly from this review, and join calls for a broadening of our intellectual investment in Aboriginal health.
Workflow nets for tasks generation and distribution in electronic education
Creators: name: Gurung, Neelu
Publisher: name: RWTH Aachen University
Year: 2021
Subjects: subject: 004

description: Masterarbeit, RWTH Aachen University, 2021; Aachen : RWTH Aachen University 1 Online-Ressource : Illustrationen, Diagramme (2021). doi:10.18154/RWTH-2022-07118 = Masterarbeit, RWTH Aachen University, 2021
description: Published by RWTH Aachen University, Aachen
Creating ‘Partnership in iSupport program’ to optimise family carers’ impact on dementia care: a randomised controlled trial protocol
Creators: name: Xiao, L
name: Yu, Y
name: Ratcliffe, J
name: Milte, R
name: Meyer, Claudia
name: Chapman, M
name: Chen, L
name: Ullah, S
name: Kitson, A
name: De Andrade, AQ
name: Beattie, E
name: Brodaty, H
name: McKechnie, S
name: Low, LF
name: Nguyen, TA
name: Whitehead, C
name: Brijnath, B
name: Sinclair, R
name: Voss, D
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems
classificationCode: 4205
subject: Nursing
classificationCode: 4206
subject: Public health

description: Background: The majority of people with dementia are cared for by their family members. However, family carers are often unprepared for their caring roles, receiving less education and support compared with professional carers. The consequences are their reduced mental and physical health and wellbeing, and that of care recipients. This study protocol introduces the ‘Partnership in iSupport program’ that includes five interventional components: managing transitions, managing dementia progression, psychoeducation, carer support group and feedback on services. This health services research is built on family carer and dementia care service provider partnerships. The aims of the study are to evaluate the effectiveness, cost-effectiveness and family carers’ experiences in the program. Methods: A multicentre randomised controlled trial will be conducted with family carers of people living with dementia from two tertiary hospitals and two community aged care providers across three Australian states. The estimated sample size is 185 family carers. They will be randomly assigned to either the intervention group or the usual care group. Outcomes are measurable improvements in quality of life for carers and people with dementia, caregiving self-efficacy, social support, dementia related symptoms, and health service use for carers and their care recipients. Data will be collected at three time points: baseline, 6 months and 12 months post-initiation of the intervention. Discussion: This is the first large randomised controlled trial of a complex intervention on health and social care services with carers of people living with dementia in real-world practice across hospital and community aged care settings in three Australian states to ascertain the effectiveness, cost-effectiveness and carers’ experiences of the innovative program. We expect that this study will address gaps in supporting dementia carers in health and social care systems while generating new knowledge of the mechanisms of change in the systems. Findings will strengthen proactive health management for both people living with dementia and their carers by embedding, scaling up and sustaining the ‘Partnership in iSupport program’ in the health and social care systems. Trial registration: The Australian New Zealand Clinical Trials Registry (ANZCTR). ACTRN12622000199718. Registered February 4th, 2022.
กระบวนการสื่อสารปรัชญาเศรษฐกิจพอเพียงในการแพร่กระจายนวัตกรรมภูมิปัญญาท้องถิ่น กรณีศึกษาศูนย์ศึกษาการพัฒนาอ่าวคุ้งกระเบน อันเนื่องมาจากพระราชดำริ
Creators: name: ภารดี พึ่งสำราญ, เสาวนีย์ วรรณประภา
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: กระบวนการสื่อสารปรัชญาเศรษฐกิจพอเพียง, การแพร่กระจายนวัตกรรมภูมิปัญญาท้องถิ่น,ศูนย์ศึกษาการพัฒนาอ่าวคุ้งกระเบน อันเนื่องมาจากพระราชดำริ,communication process of the philosophy of sufficiency economy,the diffusion of local wisdom innovation,Krabaen Bay

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
มายาคติในการสื่อสารออนไลน์ของเว็บไซต์การพนัน
Creators: name: สุระชัย ชูผกา
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: มายาคติ,การครอบงำเชิงอุดมการณ์,การสื่อสารออนไลน์,การพนันออนไลน์,Myth,Ideological Hegemony,Online Communication,Online Gambling

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
ผลลัพธ์ของการเรียนรู้จากการใช้ระบบช่วยเรียนเรื่องงบการเงินรวม
Creators: name: กิตติภรณ์ ทรัพย์รุ่งวัฒนา, อุทัย ตันละมัย
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: เทคโนโลยีส่วนประสาน,รูปแบบโจทย์แบบฝึกหัด,ระบบช่วยเรียนรู้, งบการเงินรวม,ผลลัพธ์การเรียนรู้,Interface Technology,Question Format,Computer Assisted Learning,Consolidated Financial Statement,Learning Outcome

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
การพัฒนารูปแบบปัจจัยความสำเร็จในการบริหารต้นทุนของวิสาหกิจขนาดกลางและขนาดย่อม
Creators: name: ภัทรา เรืองสินภิญญา, กฤตชน วงศ์รัตน์, โสภาพร กล่าสกุล, สมสุข แขมคำ
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: การบริหารต้นทุน,วิสาหกิจขนาดกลางและขนาดย่อม,cost management,small and medium sized enterprises

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
EJT809156_supplemental_material – Supplemental material for Do international institutions matter? Socialization and international bureaucrats
Creators: name: Murdoch, Zuzana
name: Kassim, Hussein
name: Connolly, Sara
name: Geys, Benny
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, EJT809156_supplemental_material for Do international institutions matter? Socialization and international bureaucrats by Zuzana Murdoch, Hussein Kassim, Sara Connolly and Benny Geys in European Journal of International Relations
ความแตกต่างของระดับการใช้ประโยชน์จากงบการเงินของผู้ประกอบการขนาดกลางและขนาดย่อมเพื่อการบริหารกิจการในจังหวัดอุบลราชธานี
Creators: name: ศิริรัตน์ เจนศิริศักดิ์
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: ผู้ประกอบการ, งบการเงิน, ระดับการใช้ประโยชน์, Entrepreneur, Financial Statement, utilization level

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
การเปิดเผยข้อมูลความรับผิดชอบต่อสังคมและการดำเนินงานของบริษัทจดทะเบียน ในตลาดหลักทรัพย์แห่งประเทศไทย
Creators: name: สินีนาฏ วงค์เทียนชัย
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: การเปิดเผยข้อมูลความรับผิดชอบต่อสังคม,การดำเนินงานขององค์กร,Corporate Social Responsibility Information Disclosures,Organizational Performance

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
การปรับใช้ทฤษฎีบริหารธุรกิจเอกชนเพื่อศึกษาและปรับปรุงความล้มเหลวทางการเงิน ด้านการบริหารการเงิน ด้านกระบวนการปฏิบัติงานและด้านการตลาดของโรงพยาบาลของรัฐในประเทศไทย: กรณีศึกษาโรงพยาบาลในสังกัดสำนักงานปลัดกระทรวงสาธารณสุข ประเทศไทย
Creators: name: ไอลดา สุขนาค
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: ทฤษฎีบริหารธุรกิจเอกชน,ความล้มเหลวทางการเงิน,โรงพยาบาลของรัฐ,Business Management Theories,Financial Failure,Government Hospital

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
Additional file 1 of Changes in microbial community structure and co-metabolism during the domestication of ofloxacin-degrading bacteria
Creators: name: Li, Yanhong
name: Zhang, Jing
name: Sha, Naiqing
name: Tang, Shen
name: Peng, Yuqing
name: Zhao, Yao
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. The AWCD of GD-1 on Biolog-ECO plate treated with different concentrations of OFL. Table. S1 The proportion of the main elements of the sample.
Townsend_OnlineAppendix – Supplemental material for Empowerment Through Difference: An Online Difference-Education Intervention Closes the Social Class Achievement Gap
Creators: name: Townsend, Sarah S. M.
name: Stephens, Nicole M.
name: Smallets, Stephanie
name: MarYam G. Hamedani
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Townsend_OnlineAppendix for Empowerment Through Difference: An Online Difference-Education Intervention Closes the Social Class Achievement Gap by Sarah S. M. Townsend, Nicole M. Stephens, Stephanie Smallets and MarYam G. Hamedani in Personality and Social Psychology Bulletin
Supplemental Material, DS1_VET_10.1177_0300985818806968 - Canine Mammary Tumors: Comparison of Classification and Grading Methods in a Survival Study
Creators: name: Canadas, Ana
name: França, Miguel
name: Pereira, Cristina
name: Vilaça, Raquel
name: Vilhena, Hugo
name: Tinoco, Flora
name: Silva, Maria João
name: Ribeiro, Jorge
name: Medeiros, Rui
name: Oliveira, Pedro
name: Dias-Pereira, Patrícia
name: Santos, Marta
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental Material, DS1_VET_10.1177_0300985818806968 for Canine Mammary Tumors: Comparison of Classification and Grading Methods in a Survival Study by Ana Canadas, Miguel França, Cristina Pereira, Raquel Vilaça, Hugo Vilhena, Flora Tinoco, Maria João Silva, Jorge Ribeiro, Rui Medeiros, Pedro Oliveira, Patrícia Dias-Pereira, and Marta Santos in Veterinary Pathology
กลยุทธ์การพัฒนาสมรรถนะในการปฏิบัติงานของพนักงานธนาคารออมสินภาค 7
Creators: name: ชนิกา พิพัฒนานิมิต
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: กลยุทธ์,สมรรถนะในการปฏิบัติงาน,ธนาคารออมสินภาค 7,Strategy,Workplace Competency,Government Savings Bank (GSB),Regional Office 7

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
รูปแบบความสัมพันธ์โครงสร้างเชิงสาเหตุของปัจจัยที่ส่งผลต่อกลยุทธ์การตลาด สำหรับธุรกิจแฟชั่นเครื่องนุ่งห่มไทยสู่ตลาดประชาคมเศรษฐกิจอาเซียน
Creators: name: ณัฏฐ์เอก กุลฐากรเสฏฐ์
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: รูปแบบความสัมพันธ์โครงสร้างเชิงสาเหตุ,กลยุทธ์การตลาด,ธุรกิจแฟชั่นเครื่องนุ่งห่มไทย,ตลาดอาเซียน,The Causal Structural Equation Model,Marketing Strategies,Thai Garment Fashion Business,AEC Market

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
DS_10.1177_0022034518809088 – Supplemental material for CPP-ACP Promotes SnF2 Efficacy in a Polymicrobial Caries Model
Creators: name: S.G. Dashper
name: P. Shen
name: C.P.C. Sim
name: S.W. Liu
name: C.A. Butler
name: H.L. Mitchell
name: T. D’Cruze
name: Y. Yuan
name: B. Hoffmann
name: G.D. Walker
name: D.V. Catmull
name: C. Reynolds
name: E.C. Reynolds
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, DS_10.1177_0022034518809088 for CPP-ACP Promotes SnF2 Efficacy in a Polymicrobial Caries Model by S.G. Dashper, P. Shen, C.P.C. Sim, S.W. Liu, C.A. Butler, H.L. Mitchell, T. D’Cruze, Y. Yuan, B. Hoffmann, G.D. Walker, D.V. Catmull, C. Reynolds and E.C. Reynolds in Journal of Dental Research
องค์ประกอบของการจัดซื้อจัดจ้างที่เป็นมิตรต่อสิ่งแวดล้อมในอุตสาหกรรมเครื่องปรับอากาศและเครื่องทำความเย็นในประเทศไทย
Creators: name: รัชญา ณิชากรกีรติ
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: การจัดซื้อจัดจ้างที่เป็นมิตรต่อสิ่งแวดล้อม,องค์ประกอบ,อุตสาหกรรมครื่องปรับอากาศและเครื่องทำความเย็น,Green Procurement,Components,Air-Conditioning and Refrigeration Industry

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
บทวิจารณ์หนังสือ: Information and Communication Technologies for Sustainable Tourism
Creators: name: ปรเมษฐ์ ดำชู
Publisher: name: คณะบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: Information and Communication Technologies,Sustainable Tourism

description: วารสารบริหารธุรกิจ เศรษฐศาสตร์และการสื่อสาร, 10, 2
Doğum Parası Alma
Creators: name: BALTAŞ, Recep
Publisher: name: Zenodo
Year: 2016

description: Doğum parası genelde büyük ve gelişmiş ülkelerde uygulanmaya başlanmış ve çok güzel geri dönüşler almıştır. Ülkemizde de son 2 yıldır çocuk doğum parası adı altında hamile anneler tarafından 16 haftalık süre boyunca en az 4500 tl kadar para alınıyor. Bu para özellikle 3 den fazla çocuk yapanlar için adeta bir ek gelir niteliğinde diyebiliriz. Doğum parası hatta çocuk süt parası olarak geçen bu para 2017 yılında zamlanacak. Yüzde yirmiden fazla zam gelmesi beklenen çocuk doğum parası 2017 için detaylı bir yazı yazdık ve sorularınıza konu altından yanıt veriyoruz. Hiç çekinmeden sorularınızı iletebilirsiniz.
hkj809499 – Supplemental material for Comparison of the efficacy of three cervical collars in restricting cervical range of motion: A randomized study
Creators: name: Kim, Jae Guk
name: Bang, Sung Hwan
name: Kang, Gu Hyun
name: Jang, Yong Soo
name: Wonhee Kim
name: Choi, Hyun Young
name: Gyoung Mo Kim
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine

description: Supplemental material, hkj809499 for Comparison of the efficacy of three cervical collars in restricting cervical range of motion: A randomized study by Jae Guk Kim, Sung Hwan Bang, Gu Hyun Kang, Yong Soo Jang, Wonhee Kim, Hyun Young Choi and Gyoung Mo Kim in Hong Kong Journal of Emergency Medicine
Supplemental_Figures_(1) – Supplemental material for Anti-proliferative and anti-inflammatory activities of the sea cucumber Holothuria polii aqueous extract
Creators: name: Kareh, Mike
name: Nahas, Rana El
name: Al-Aaraj, Lamis
name: Al-Ghadban, Sara
name: Deen, Nataly Naser Al
name: Saliba, Najat
name: El-Sabban, Marwan
name: Talhouk, Rabih
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, Supplemental_Figures_(1) for Anti-proliferative and anti-inflammatory activities of the sea cucumber Holothuria polii aqueous extract by Mike Kareh, Rana El Nahas, Lamis Al-Aaraj, Sara Al-Ghadban, Nataly Naser Al Deen, Najat Saliba, Marwan El-Sabban and Rabih Talhouk in SAGE Open Medicine
Supplemental Material, Appendix_A_Risk_Markers_for_IT_and_SCV - Perpetrator Risk Markers for Intimate Terrorism and Situational Couple Violence: A Meta-Analysis
Creators: name: Love, Heather A.
name: Spencer, Chelsea M.
name: May, Scott A.
name: Mendez, Marcos
name: Stith, Sandra M.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, Appendix_A_Risk_Markers_for_IT_and_SCV for Perpetrator Risk Markers for Intimate Terrorism and Situational Couple Violence: A Meta-Analysis by Heather A. Love, Chelsea M. Spencer, Scott A. May, Marcos Mendez, and Sandra M. Stith in Trauma, Violence, & Abuse
OSJ808669_Supplementary_material - Treatment modalities for hip and knee osteoarthritis: A systematic review of safety
Creators: name: Aweid, Osama
name: Haider, Zakir
name: Saed, Abdel
name: Yegappan Kalairajah
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: OSJ808669_Supplementary_material for Treatment modalities for hip and knee osteoarthritis: A systematic review of safety by Osama Aweid, Zakir Haider, Abdel Saed, and Yegappan Kalairajah in Journal of Orthopaedic Surgery
title: Mobilisierung statt Solutionismus: Gender im Diskurs um KI und Arbeit
Creators: name: Carstensen, Tanja
name: Ganz, Kathrin
Publisher: name: DuEPublico
Year: 2024
Subjects: classificationCode: 5
subject: FOS: Social sciences
subject: Gender studies

description: Eine Stärke sozialwissenschaftlicher Technikforschung ist, dass sie immer wieder technikdeterministische Kurzschlüsse entlarvt. Auch mit Blick auf Geschlecht hat sie wiederholt herausgearbeitet, inwiefern öffentlichen Diskursen, verheißungsvollen Visionen aus den Zentren der Tech-Entwicklung und politischen Förder- und Investitionsbemühungen simplifizierende technikdeterministische und auch techniksolutionistische Deutungsmuster zugrunde liegen. Technik wird darin eine hohe (einseitige und unverhandelbare) Wirkmacht auf Gesellschaft zugeschrieben und darüber hinaus als Lösung für gesellschaftliche Probleme präsentiert.
AUT811329_Supplemental_material – Supplemental material for Clinical correlates of sluggish cognitive tempo in adolescents with autism spectrum disorder
Creators: name: Duncan, Amie
name: Tamm, Leanne
name: Birnschein, Allison M
name: Becker, Stephen P
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: Education
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental material, AUT811329_Supplemental_material for Clinical correlates of sluggish cognitive tempo in adolescents with autism spectrum disorder by Amie Duncan, Leanne Tamm, Allison M Birnschein and Stephen P Becker in Autism
Toward just and equitable micro-credentials: an Australian perspective
Creators: name: Desmarchelier, R
name: Cary, Lisa
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 39
subject: Education
classificationCode: 3904
subject: Specialist studies in education

description: The current historic COVID-19 Pandemic moment has thrown into sharp relief the need for flexible and rigorous higher education that meets upskilling and reskilling needs of global workforces. Discussions of micro-credentialing predate the Pandemic but have received increased focus as potentially assisting in addressing perceived skills gaps. However, not all commentators have been complimentary about the possibilities inherent in micro-credentialing. In this paper we discuss Ralston (Postdigital Science and Education 3:83–101, 2021) criticism of the “microcredentialing craze” as provocation to consider how equitable, thoughtful and just educative aims may be met. We address Ralston’s argument that micro-credentials present an educative “moral hazard” by arguing that micro-credentialing will allow universities to respond quickly to changing worker educational needs rather than only offering full degrees that may not be economically viable or personally desirable for individuals. Rather, we suggest, the potential of micro-credentials lies in their pathways and potential to enhance lifelong learning and suggest that micro-credentials do not stand outside of the pedagogical ethical imperative that learning experiences should be positive and inclusive.
Integrated Deadenylase Genetic Association Network and Transcriptome Analysis in Thoracic Carcinomas
Creators: name: Kyritsis, A
name: Papanastasi, E
name: Kokkori, I
name: Maragozidis, P
name: Chatzileontiadou, Dimitra
name: Pallaki, P
name: Labrou, M
name: Zarogiannis, SG
name: Chrousos, GP
name: Vlachakis, D
name: Gourgoulianis, KI
name: Balatsos, NAA
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences
classificationCode: 3404
subject: Medicinal and biomolecular chemistry
classificationCode: 3405
subject: Organic chemistry

description: The poly(A) tail at the 3′ end of mRNAs determines their stability, translational efficiency, and fate. The shortening of the poly(A) tail, and its efficient removal, triggers the degradation of mRNAs, thus, regulating gene expression. The process is catalyzed by a family of enzymes, known as deadenylases. As the dysregulation of gene expression is a hallmark of cancer, understanding the role of deadenylases has gained additional interest. Herein, the genetic association network shows that CNOT6 and CNOT7 are the most prevalent and most interconnected nodes in the equilibrated diagram. Subsequent silencing and transcriptomic analysis identifies transcripts possibly regulated by specific deadenylases. Furthermore, several gene ontologies are enriched by common deregulated genes. Given the potential concerted action and overlapping functions of deadenylases, we examined the effect of silencing a deadenylase on the remaining ones. Our results suggest that specific deadenylases target unique subsets of mRNAs, whilst at the same time, multiple deadenylases may affect the same mRNAs with overlapping functions.