cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Two-Year Survival Comparing Web-Based Symptom Monitoring vs Routine Surveillance Following Treatment for Lung Cancer
Creators: name: Septans, A.-L.
name: Denis, F.
name: Bennouna, J.
name: Letellier, C.
name: Dueck, A.C.
name: Urban, T.
name: Basch, E.
Publisher: name: American Medical Association
Year: 2019

description: Symptom monitoring during chemotherapy via web-based patient-reported outcomes (PROs) was previously demonstrated to lengthen survival in a single-center study. A multicenter randomized clinical trial comparedweb-based monitoring vs standard scheduled imaging to detect symptomatic recurrence in patients with lung cancer following initial treatment. A planned interim analysis (9-month follow-up) founda significant survival benefit (19-month survival in the PRO group vs 12 months in the control group). We now present the final overall survival analysis.
КИБЕРЖИНОЯТЛАР ДОИРАСИДА СОДИР ЭТИЛГАН ҲУҚУҚБУЗАРЛИКЛАРНИНГ МАХСУС ПРОФИЛАКТИКАСИ БЎЙИЧА ФАОЛИЯТИНИ ТАКОМИЛЛАШТИРИШ
Creators: name: Мустофақулов, Бобур
name: Сатторов, Шахзоджон
Publisher: name: Zenodo
Year: 2025

description: Ушбу мақолада кибержиноятларнинг вужудга келиши тарихи, кибержиноятнинг тушунчаси ва турлари, кибержиноятчилик ҳақида олимларнинг фикрлари ва киберхавфсизлик тўғрисидаги қонуни, махсус профилактикани амалга ошириш йўллари ҳақида сўз юритилади.
Methodology for automated generation of 4D BIM
Creators: name: Montaser, A.
name: Moselhi, O.
Publisher: name: The University of British Columbia
Year: 2015

description: Lack of adequate visualization of project construction operations often causes project parties to struggle with large amount of data. 3D Building Information Modeling (BIM) is a static model, built for representing the geometry of a constructed building and its respective information. However, construction processes are dynamic and require dynamic representation. 4D BIM is gaining more momentum in construction research and in industry. There are commercial packages that can generate 4D BIM and numerous researchers have used 4D BIM in their research. However, related literature does not disclose the methodology used or the know-how of creating 4D BIM. This paper presents an automated methodology and describes how to construct a 4D BIM. The automated methodology maps the 3D BIM objects to project schedule activities through a newly added attribute to each 3D BIM object. As such, different groups of objects within the 3D BIM are assigned to different activities. For each group, a series of decisions are made to classify whether it belongs to completed activity, activity in progress or activity to be executed in the future. The developed methodology was implemented in prototype software. Autodesk Revit has been customized so that the integration between 3D BIM and project schedule be applied using Revit Application Programming Interface (API). The developed automated methodology and software were applied to a construction project in Montreal area to demonstrate its use. The developed methodology is straightforward and easy to use. It is expected to facilitate the utilization of 4D BIM in research and in practice.
Analyzing Robustness of Angluin's L$^*$ Algorithm in Presence of Noise
Creators: name: Ye, Lina
name: Khmelnitsky, Igor
name: Haddad, Serge
name: Barbot, Benoît
name: Bollig, Benedikt
name: Leucker, Martin
name: Neider, Daniel
name: Roy, Rajarshi
Publisher: name: arXiv
Year: 2023
Subjects: subject: Formal Languages and Automata Theory (cs.FL)
subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: Angluin's L$^*$ algorithm learns the minimal deterministic finite automaton (DFA) of a regular language using membership and equivalence queries. Its probabilistic approximatively correct (PAC) version substitutes an equivalence query by numerous random membership queries to get a high level confidence to the answer. Thus it can be applied to any kind of device and may be viewed as an algorithm for synthesizing an automaton abstracting the behavior of the device based on observations. Here we are interested on how Angluin's PAC learning algorithm behaves for devices which are obtained from a DFA by introducing some noise. More precisely we study whether Angluin's algorithm reduces the noise and produces a DFA closer to the original one than the noisy device. We propose several ways to introduce the noise: (1) the noisy device inverts the classification of words w.r.t. the DFA with a small probability, (2) the noisy device modifies with a small probability the letters of the word before asking its classification w.r.t. the DFA, (3) the noisy device combines the classification of a word w.r.t. the DFA and its classification w.r.t. a counter automaton, and (4) the noisy DFA is obtained by a random process from two DFA such that the language of the first one is included in the second one. Then when a word is accepted (resp. rejected) by the first (resp. second) one, it is also accepted (resp. rejected) and in the remaining cases, it is accepted with probability 0.5. Our main experimental contributions consist in showing that: (1) Angluin's algorithm behaves well whenever the noisy device is produced by a random process, (2) but poorly with a structured noise, and, that (3) is able to eliminate pathological behaviours specified in a regular way. Theoretically, we show that randomness almost surely yields systems with non-recursively enumerable languages.
description: arXiv admin note: substantial text overlap with arXiv:2209.10315
การส่งเสริมบทบาทกลุ่มสตรีในการพัฒนาเศรษฐกิจ สังคมและวัฒนธรรมในชุมชนท้องถิ่นของเทศบาลตำบลกุดดู่ เทศบาลตำบลโนนสัง เทศบาลตำบลโคกศรี เทศบาลตำบลยางตลาด เทศบาลตำบลหนองหิน และเทศบาลตำบลกกกุง
Creators: name: ลักคณา โยคะวิสัย และ จุมพล หนิมพานิช
Publisher: name: มหาวิทยาลัยรังสิต
Year: 2016
Subjects: การส่งเสริม, ทฤษฎีสตรีนิยม, ทฤษฎีวัฒนธรรมศึกษา

description: 2, 1, วารสารรังสิตบัณฑิตศึกษาในกลุ่มธุรกิจและสังคมศาสตร์
กลยุทธ์การสร้างความจงรักภักดีของแฟนบอลกรณีศึกษา สโมสรฟุตบอลชลบุรี เอฟซี.
Creators: name: กุลิสรา ภู่ระหงษ์
Publisher: name: มหาวิทยาลัยรังสิต
Year: 2016
Subjects: กลยุทธ์การสร้างความจงรักภักดี, แฟนบอล,สโมสรฟุตบอล,ชลบุรี เอฟซี

description: 2, 1, วารสารรังสิตบัณฑิตศึกษาในกลุ่มธุรกิจและสังคมศาสตร์
Supplementary document for Modal properties of dielectric bowtie cavities with deep sub-wavelength confinement - 6099401.pdf
Creators: name: Kountouris, George
name: Mørk, Jesper
name: Denning, Emil
name: Kristensen, Philip
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document 1
An Investigation of Factors Influencing Service Quality of Commercial Bank: A Case Study in China
Creators: name: Zhenyan Qin And Pitsamorn Kilenthong
Publisher: name: มหาวิทยาลัยรังสิต
Year: 2016
Subjects: SERVQUAL, commercial banks, satisfaction, CSR, WOM, loyalty

description: 2, 1, วารสารรังสิตบัณฑิตศึกษาในกลุ่มธุรกิจและสังคมศาสตร์
Patient-reported outcome monitoring in a routine paediatric oncology setting: challenges and opportunities
Creators: name: Calvert, M.
name: Kaur, G.
name: Reeve, B.B.
name: Kyte, D.
name: Basch, E.
Publisher: name: Lancet Publishing Group
Year: 2019

description: Cancer affects one in every 500 children younger than 15 years in the UK, and around 1800 new cases are diagnosed in this population every year. Despite advances in treatments and improved overall survival, children with cancer have a high symptom burden, related both to the underlying cancer and associated treatments that can substantially affect their physical, mental, social, and emotional wellbeing, and cognitive function. Moreover, there are major psychosocial and financial implications for families of children with cancer, and substantial societal health-care costs.
RD 5: Designing Circular Products - Using System Mapping & Simulation
Creators: name: Schreiner, Sabrina
name: Meller, Patrick
name: Schulte, Anna
name: :Unav
Publisher: name: Fraunhofer-Gesellschaft
Year: 2021
Subjects: circular economy
product
sustainable

description: Simulating different closing-the-loop strategies: Determine your optimal strategy mix by examining short- and long-term impacts on environmental and economic factors.
Numerical signatures of ultra-local criticality in a one dimensional Kondo lattice model
Creators: name: Nikolaenko, Alexander
name: Zhang, Ya-Hui
Publisher: name: arXiv
Year: 2023
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Heavy fermion criticality has been a long-standing problem in condensed matter physics. Here we study a one-dimensional Kondo lattice model through numerical simulation and observe signatures of local criticality. We vary the Kondo coupling $J_K$ at fixed doping $x$. At large positive $J_K$, we confirm the expected conventional Luttinger liquid phase with $2k_F=\frac{1+x}{2}$ (in units of $2π$), an analogue of the heavy Fermi liquid (HFL) in the higher dimension. In the $J_K \leq 0$ side, our simulation finds the existence of a fractional Luttinger liquid (LL*) phase with $2k_F=\frac{x}{2}$, accompanied by a gapless spin mode originating from localized spin moments, which serves as an analogue of the fractional Fermi liquid (FL*) phase in higher dimensions. The LL* phase becomes unstable and transitions to a spin-gapped Luther-Emery (LE) liquid phase at small positive $J_K$. Then we mainly focus on the `critical regime' between the LE phase and the LL phase. Approaching the critical point from the spin-gapped LE phase, we often find that the spin gap vanishes continuously, while the spin-spin correlation length in real space stays finite and small. For a certain range of doping, in a point (or narrow region) of $J_K$, the dynamical spin structure factor obtained through the time-evolving block decimation (TEBD) simulation shows dispersion-less spin fluctuations in a finite range of momentum space above a small energy scale (around $0.035 J$) that is limited by the TEBD accuracy. All of these results are unexpected for a regular gapless phase (or critical point) described by conformal field theory (CFT). Instead, they are more consistent with exotic ultra-local criticality with an infinite dynamical exponent $z=+\infty$. Lastly, we propose to simulate the model in a bilayer optical lattice with a potential difference.
description: 23 pages, 27 figures
The Evolving Uses of "Real-World" Data
Creators: name: Basch, E.
name: Schrag, D.
Publisher: name: NLM (Medline)
Year: 2019

description: The terms real-world data (RWD) and real-world evidence (RWE) have entered the medical lexicon to refer to data sources and analyses characterizing routine health care delivery. RWD and RWE are most often defined by what they are not: information from experiments such as randomized clinical trials.
Cost-Effectiveness of Web-Based Patient-Reported Outcome Surveillance in Patients With Lung Cancer
Creators: name: Domont, J.
name: Lizée, T.
name: Basch, E.
name: Septans, A.-L.
name: Detournay, B.
name: Trémolières, P.
name: Denis, F.
name: Peyraga, G.
name: Voog, E.
name: Bennouna, J.
name: Urban, T.
name: Balavoine, M.
Publisher: name: Elsevier Inc
Year: 2019

description: Introduction: A multicenter randomized clinical trial in France found an overall survival benefit of web-based patient-reported outcome (PRO)–based surveillance after initial treatment for lung cancer compared with conventional surveillance. The aim of this study was to assess the cost-effectiveness of this PRO-based surveillance in lung cancer patients. Methods: This medico-economic analysis used data from the clinical trial, augmented by abstracted chart data and costs of consultations, imaging, transportations, information technology, and treatments. Costs were calculated based on actual reimbursement rates in France, and health utilities were estimated based on scientific literature review. Willingness-to-pay thresholds of €30,000 per quality-adjusted life year (QALY) and €90,000 per QALY were used to define a very cost-effective and cost-effective strategy, respectively. Average annual costs of experimental and control surveillance approaches were calculated. The incremental cost-effectiveness ratio was expressed as cost per life-year gained and QALY gained, from the health insurance payer perspective. One-way and multivariate probabilistic sensitivity analyses were performed. Results: Average annual cost of surveillance follow-up was €362 lower per patient in the PRO arm (€941/year/patient) compared to control (€1,304/year/patient). The PRO approach presented an incremental cost-effectiveness ratio of €12,127 per life-year gained and €20,912 per QALY gained. The probabilities that the experimental strategy is very cost-effective and cost-effective were 97% and 100%, respectively. Conclusions: Surveillance of lung cancer patients using web-based PRO reduced the follow-up costs. Compared to conventional monitoring, this surveillance modality represents a cost-effective strategy and should be considered in cancer care delivery.
Static-Equilibrium Oriented Interaction Force Modeling and Control of Aerial Manipulation with Uni-Directional Thrust Multirotors
Creators: name: Hui, Tong
name: Fumagalli, Matteo
Publisher: name: arXiv
Year: 2023
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: This paper presents a static-equilibrium oriented interaction force modeling and control approach of aerial manipulation employing uni-directional thrust (UDT) multirotors interacting with variously defined environments. First, a simplified system model for a quadrotor-based aerial manipulator is introduced considering parameterized work surfaces under assumptions, and then a range of meaningful manipulation tasks are utilized to explore the system properties in a quasi-static equilibrium state. An explicit interaction force model in relation with the aerial manipulator pose configuration and the environment parameter is derived from the static equilibrium analysis, based on which singularity is pointed out. Then a hybrid attitude/force interaction control strategy is presented to verify the proposed interaction force model, which involves high gain attitude control and feedforward plus feedback force control. This paper represents preliminary results. We study the properties of UDT-based aerial manipulators via specific tasks, and propose a novel framework for interaction force modeling and control aiming at maximizing the commercial values of UDT platforms for aerial manipulation purpose.
ปัจจัยทางเศรษฐกิจที่กำหนดอัตราแลกเปลี่ยนระหว่างเงินบาทกับเงินหยวน
Creators: name: กรรณิกา ศรีสังข์งาม และ กิตติพันธ์ คงสวัสดิ์เกียรติ
Publisher: name: มหาวิทยาลัยรังสิต
Year: 2016
Subjects: อัตราแลกเปลี่ยน, เงินตราต่างประเทศ, เงินบาท, เงินหยวน

description: 2, 1, วารสารรังสิตบัณฑิตศึกษาในกลุ่มธุรกิจและสังคมศาสตร์
Integrating building information modeling and conceptual design towards effective facilities management : a framework title
Creators: name: Al-Kattan, Elaf
name: Jrade, Ahmad
Publisher: name: The University of British Columbia
Year: 2015

description: The engagement of Facilities Management (FM) during the conceptual design stage of building projects has been recently explored. Incorporating FM during the design stage through the concept of BIM has the potential to minimize the possible waste of project resources (time, money, materials, and sustainability impacts) especially during the operational stage while offering the essential tools to keep buildings running to the required living standards. This paper proposes a framework to develop an integrated conceptual design model towards effective FM. Based on an intense literature review and series of interviews with FM and design professionals, this innovative framework is created to fulfil the following basics attributes: (1) tackling the key factors that affect FM; (2) Identifying the most effective stage of design (conceptual design) to involve facility managers; and (3) Detecting the major aspects that will directly contribute in enhancing the quality of managing, operating and maintaining facilities at the early design stage of a project. The expected results of the integrated BIM-FM model should show the importance of facilities managers’ contribution during the conceptual design stage that leads in reducing the operating and maintenance costs, while providing 3D Integrated Design within Building Information Modeling (BIM) environment by generating list of design alternatives through design simulations. An actual case project is used to test the models’ capability and workability.
Commentary on King-Kallimanis et al.: Inadequate measurement of symptomatic adverse events in immunotherapy registration trials
Creators: name: Leahy, A.B.
name: Basch, E.
Publisher: name: SAGE Publications Ltd
Year: 2019

description: Symptomatic adverse events are common with cancer therapies, and provide key information about tolerability during development and regulatory review. After a therapy becomes available on the market, information about these adverse events is essential for patient and clinician decision-making. Historically, the standard approach for collecting symptomatic adverse events in trials depended on clinician reporting via the National Cancer Institute’s (NCI) Common Terminology Criteria for Adverse Events (CTCAE)—but this process was found to be unreliable and to miss about half of patients’ symptoms.
กลยุทธ์ส่วนประสมทางการตลาดบริการที่มีผลต่อการตัดสินใจเลือกใช้บริการร้านเบเกอรี่ย่านซอยทองหล่อในเขตกรุงเทพมหานคร
Creators: name: กุสุมา ปิยโพธิกุล และ ถนอม พงษ์พานิช
Publisher: name: มหาวิทยาลัยรังสิต
Year: 2016
Subjects: ส่วนประสมทางการตลาดบริการ, ร้านเบเกอรี่, ย่านซอยทองหล่อ

description: 2, 1, วารสารรังสิตบัณฑิตศึกษาในกลุ่มธุรกิจและสังคมศาสตร์
Stabilization of symmetry-protected long-range entanglement in stochastic quantum circuits
Creators: name: Angelidi, Iosifina
name: Szyniszewski, Marcin
name: Pal, Arijeet
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Long-range entangled states are vital for quantum information processing and quantum metrology. Preparing such states by combining measurements with unitary gates opened new possibilities for efficient protocols with finite-depth quantum circuits. The complexity of these algorithms is crucial for the resource requirements on a large-scale noisy quantum device, while their stability to perturbations decides the fate of their implementation. In this work, we consider stochastic quantum circuits in one and two dimensions comprising randomly applied unitary gates and local measurements. These operations preserve a class of discrete local symmetries, which are broken due to the stochasticity arising from timing and gate imperfections. In the absence of randomness, the protocol generates a symmetry-protected long-range entangled state in a finite-depth circuit. In the general case, by studying the time evolution under this hybrid circuit, we analyze the time to reach the target entangled state. We find two important time scales that we associate with the emergence of certain symmetry generators. The quantum trajectories embody the local symmetry with a time scaling logarithmically with system size, while global symmetries require exponentially long times. We devise error-mitigation protocols that significantly lower both time scales and investigate the stability of the algorithm to perturbations that naturally arise in experiments. We also generalize the protocol to realize toric code and Xu-Moore states in two dimensions, opening avenues for future studies of anyonic excitations. Our results unveil a fundamental relationship between symmetries and dynamics across a range of lattice geometries, which contributes to a broad understanding of the stability of preparation algorithms in terms of phase transitions. Our work paves the way for efficient error correction for quantum state preparation.
description: 23 pages, 20 figures, 1 table
Mentoria para o Parque Tecnológico de Maricá - 2024
Creators: name: TODA, FAVIO AKIYOSHI
Publisher: name: Zenodo
Year: 2025

description: Mentoria para empresas incubadas no Parque Tecnológico de Maricá realizada em 2024. Entre as empresas que continuaram incubadas em 2025, a mentoria continua para com a empresa 4Team.
การให้บริการสาธารณะที่ส่งผลต่อความสำเร็จเทศบาลนครของไทย
Creators: name: ภาณุพงศ์ ศิริ
Publisher: name: มหาวิทยาลัยรังสิต
Year: 2016
Subjects: บริการสาธารณะ, เทศบาลนครของไทย

description: 2, 1, วารสารรังสิตบัณฑิตศึกษาในกลุ่มธุรกิจและสังคมศาสตร์
Ambulatory cancer care electronic symptom self-reporting (ACCESS) for surgical patients: A randomised controlled trial protocol
Creators: name: Stetson, P.D.
name: Carter, J.
name: Temple, L.K.
name: Stabile, C.
name: Basch, E.
name: Pusic, A.L.
name: Simon, B.A.
name: Miranda, M.
name: Vickers, A.
name: Ancker, J.S.
name: Stein, D.
Publisher: name: BMJ Publishing Group
Year: 2019

description: Introduction An increasing proportion of cancer surgeries are ambulatory procedures requiring a stay of 1 day or less in the hospital. Providing patients and their caregivers with ongoing, real-time support after discharge aids delivery of high-quality postoperative care in this new healthcare environment. Despite abundant evidence that patient self-reporting of symptoms improves quality of care, the most effective way to monitor and manage this self-reported information is not known. Methods and analysis This is a two-armed randomised, controlled trial evaluating two approaches to the management of patient-reported data: (1) team monitoring, symptom monitoring by the clinical team, with nursing outreach if symptoms exceed normal limits, and (2) enhanced feedback, real-time feedback to patients about expected symptom severity, with patient-activated care as needed. Patients with breast, gynaecologic, urologic, and head and neck cancer undergoing ambulatory cancer surgery (n=2750) complete an electronic survey for up to 30 days after surgery that includes items from a validated instrument developed by the National Cancer Institute, the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE). Information provided to patients in the Enhanced Feedback group is procedure-specific and based on updated PRO-CTCAE data from previous patients. Qualitative interviews are also performed. The primary study outcomes assess unplanned emergency department visits and symptom-triggered interventions (eg, nursing calls and pain management referrals) within 30 days, and secondary outcomes assess the patient and caregiver experience (ie, patient engagement, patient anxiety and caregiver burden). Ethics and dissemination This study is approved by the Institutional Review Board at Memorial Sloan Kettering Cancer Center. The relationships between the study team and stakeholders will be leveraged to disseminate study findings. Findings will be relevant in designing future coordinated care models targeting improved healthcare quality and patient experience. Trial registration number NCT03178045.
Mentoria para o Parque Tecnológico de Maricá - 2024
Creators: name: TODA, FAVIO AKIYOSHI
Publisher: name: Zenodo
Year: 2025

description: Mentoria destinada ao alinhamento estratégico e escalabilidade de startups incubadas no OCA HUB - Galpão Tecnológico de Maricá, mantido pela Codemar e Prefeitura Municipal de Maricá.

A mentoria se dá pela aplicação de uma metodologia própria baseada em um referencial teórico da área de estratégia com o desenvolvimento de competências dinâmicas e visão baseada em recursos, e aplicação dos conceitos em Marketing. Trata-se de um resultado da experiência tanto acadêmica como profissional em empresas de grande porte na área de Marketing e Estratégia.

Ao todo, foram mentorados 10 projetos de empresas no galpão tecnológico de Maricá: ESPERANCAR, IRRIGA-KIT, CAPACITANDO MOTORISTAS, Master Bond Cola Cimentícia, BI para pequenos negócios, Microbiota Health, Noah Smart City, Vida Pet - by Lili Apps, NanoTex – Smart Materials, Move ae!.

O projeto BI para pequenos negócios passou a se chamar 4TEAM. O qual a empreendedora Cláudia Valença de Azevedo passou a continuar recebendo atendimento.
Disorder-induced topological quantum phase transitions in multi-gap Euler semimetals
Creators: name: Jankowski, Wojciech J.
name: Noormandipour, Mohammadreza
name: Bouhon, Adrien
name: Slager, Robert-Jan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the effect of disorder in systems having a non-trivial Euler class. As these recently proposed multi-gap topological phases come about by braiding non-Abelian charged band nodes residing between different bands to induce stable pairs within isolated band subspaces, novel properties may be expected. Namely, a~modified stability and critical phases under the unbraiding to metals can arise, when the disorder preserves the underlying $C_2\cal{T}$ or $\cal{P}\cal{T}$ symmetry on average. Employing elaborate numerical computations, we verify the robustness of associated topology by evaluating the changes in the average densities of states and conductivities for different types of disorders. Upon performing a scaling analysis around the corresponding quantum critical points we retrieve a universality for the localization length exponent of $ν= 1.4 \pm 0.1$ for Euler-protected phases, relating to two-dimensional percolation models. We generically find that quenched disorder drives Euler semimetals into critical metallic phases. Finally, we show that magnetic disorder can also induce topological transitions to quantum anomalous Hall plaquettes with local Chern numbers determined by the initial value of the Euler invariant.
description: 6+11 pages, 4+9 figures
A new sufficient condition for a 2-strong digraph to be Hamiltonian
Creators: name: Darbinyan, Samvel Kh.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: In this paper we prove the following new sufficient condition for a digraph to be Hamiltonian:
 {\it Let $D$ be a 2-strong digraph of order $n\geq 9$.
 If $n-1$ vertices of $D$ have degrees at least $n+k$ and the remaining vertex has degree at least $n-k-4$, where $k$ is a non-negative integer, then $D$ is Hamiltonian}.
 This is an extension of Ghouila-Houri's theorem for 2-strong digraphs and is a generalization of an early result of the author (DAN Arm. SSR (91(2):6-8, 1990). The obtained result is best possible in the sense that for $k=0$ there is a digraph of order $n=8$ (respectively, $n=9$) with the minimum degree $n-4=4$ (respectively, with the minimum $n-5=4$) whose $n-1$ vertices have degrees at least $n-1$, but it is not Hamiltonian.
 We also give a new sufficient condition for a 3-strong digraph to be Hamiltonian-connected.
description: 20 pages, 2 figures
Recomendações estratégicas e mercadológicas para empresas incubadas no Parque Tecnológico de Maricá - 2024
Creators: name: TODA, FAVIO AKIYOSHI
Publisher: name: Zenodo
Year: 2025

description: Resultado de mentorias destinada ao alinhamento estratégico e escalabilidade de startups incubadas no OCA HUB - Galpão Tecnológico de Maricá, mantido pela Codemar e Prefeitura Municipal de Maricá.

A mentoria aconteceu pela aplicação de uma metodologia própria baseada em um referencial teórico da área de estratégia com o desenvolvimento de competências dinâmicas e visão baseada em recursos, e aplicação dos conceitos em Marketing. Trata-se de um resultado da experiência tanto acadêmica como profissional em empresas de grande porte na área de Marketing e Estratégia.

Ao todo, foram mentorados 10 projetos de empresas no galpão tecnológico de Maricá: ESPERANCAR, IRRIGA-KIT, CAPACITANDO MOTORISTAS, Master Bond Cola Cimentícia, BI para pequenos negócios, Microbiota Health, Noah Smart City, Vida Pet - by Lili Apps, NanoTex – Smart Materials, Move ae!.

O projeto "BI para pequenos negócios" passou a se chamar 4TEAM. O qual a empreendedora Cláudia Valença de Azevedo passou a continuar recebendo atendimento de mentoria.
การจัดการงานพัสดุที่มีประสิทธิผลของเทศบาลนครปากเกร็ด จังหวัดนนทบุรี
Creators: name: พรทิพย์ ชั้นบุญ
Publisher: name: มหาวิทยาลัยรังสิต
Year: 2016
Subjects: การจัดการงานพัสดุ, ประสิทธิผล

description: 2, 1, วารสารรังสิตบัณฑิตศึกษาในกลุ่มธุรกิจและสังคมศาสตร์
Surrogate End Points and Patient-Reported Outcomes for Novel Oncology Drugs Approved between 2011 and 2017
Creators: name: Nabhan, C.
name: Basch, E.
name: Zettler, M.
Publisher: name: American Medical Association
Year: 2019

description: The US Food and Drug Administration (FDA) may approve drugs based on surrogate end points that reasonably predict that a drug provides clinical benefit. If approved via the accelerated approval pathway, the FDA may require postmarketing studies to confirm the perceived clinical benefit. Assessment of patient-reported outcomes (PROs), defined as any report on a patient’s health that comes directly from the patient, can also play a key role in understanding benefits and tolerability of oncology drugs. We sought to examine the use of surrogate end points for overall survival (OS) in new oncology drug approvals, to evaluate the use of PROs in trials supporting approvals, and to determine whether oncology drugs initially approved without evidence of OS or PRO benefits demonstrated improvements in either measure postapproval.
Erkrankungen der Schilddrüse bei einer familiären adenomatösen Polyposis
Creators: name: Menke, Annika
Publisher: name: Universitäts- und Landesbibliothek Bonn
Year: 2024
Subjects: subject: familiäre adenomatöse Polyposis
subject: FAP
subject: Schilddrüsenkarzinom
subject: APC-Gen
subject: Autoimmunthyreoiditis
subject: Hypothyreose
subject: erbliche Darmkrebserkrankung
subject: Kolorektales Karzinom
subject: Screening der Schilddrüse
subject: ddc:610

description: Die familiäre adenomatöse Polyposis (FAP) ist mit einem erheblichen Lebenszeitrisiko für Schilddrüsenkarzinome und gutartige Schilddrüsenerkrankungen verbunden. Die Richtlinien für Screening und Überwachung sind international uneinheitlich. In bisherigen Studien wurde vor allem das Schilddrüsenkarzinom betrachtet.
 Das Ziel dieser Studie war die Bewertung der Prävalenz des Schilddrüsenkarzinoms und gutartiger Schilddrüsenerkrankungen sowie die Definition möglicher Überwachungsintervalle.
 Es wurden 187 Proband*innen mit FAP im Nationalen Zentrum für erbliche Tumorerkrankungen des Universitätsklinikums Bonn im Zeitraum von Juli 2010 bis September 2020 im Hinblick auf Veränderungen der Schilddrüse untersucht. Zur Auswertung der gewonnen Daten wurden deskriptive Verfahren, der Chi-quadrat-Test, der exakte Test nach Fisher, der Welsh-Test sowie der ungepaarte T-Test angewandt.
 Die endokrinologische Untersuchung ergab bei 32/187 (17 %) einen Hypothyreoidismus. Bei 85/187 Patient*innen (46 %) wurden Schilddrüsenknoten entdeckt, wobei Frauen statistisch signifikant häufiger betroffen waren (54/99 gegenüber 31/87; p=0,01). Ein Schilddrüsenkarzinom wurde bei 7/187 Proband*innen diagnostiziert. Spezifisch beim Schilddrüsenkarzinom waren Mutationen der Codone 900 und 1235. Eine Autoimmunthyreoiditis (AIT) wurde bei 28/187 (15 %) Patient*innen diagnostiziert, darunter ein Patient mit Schilddrüsenkrebs. Wobei weibliche Patientinnen statistisch signifikant (21/99 vs. 7/87; p=0,012) häufiger betroffen waren. Als spezifisch für die Entwicklung einer AIT zeigten sich Mutationen der Codone 298, 461, 615, 855, 877, 876 und 1134. Bei 101 Patient*innen wurde eine Überwachungsuntersuchung in einem Abstand von ein bis zwei Jahren durchgeführt. Bei unauffälligen Indexuntersuchung wurde kein Krebs oder keine Schilddrüsenknoten in der Kontrolluntersuchung beobachtet.
 Patient*innen mit FAP haben neben dem erhöhten Risiko eines Schilddrüsenkarzinoms auch ein erhöhtes Risiko für benigne Erkrankungen der Schilddrüse. Hierbei sind vor allem jungen weibliche Probandinnen mit Mutation am 5´Ende des APC-Gens betroffen. Die Daten zeigen, dass bei einer unauffälligen Indexuntersuchung die Erweiterung des Untersuchungsintervalls möglich ist.
Motivation for interface management in contruction : a project complexity perspective
Creators: name: Ahn, Seungjun
name: Shokri, Samin
name: Lee, SangHyun
name: Haas, Carl T.
name: Haas, Ralph C. G.
Publisher: name: The University of British Columbia
Year: 2015

description: Understanding project complexity is crucial for determining—or designing—the tools, methods, and skills required to effectively deal with interface issues in a construction project. However, understanding project complexity is not an easy undertaking; the concept of project complexity is composed of many interrelated sub-concepts, and thus is complex in itself. Given this background, this research aimed to define the dimensions of project complexity based on empirical data focusing on the variations in the project complexity factors between projects. To achieve this research objective, data for project complexity factors were collected via semi-structured interviews from 45 large-scale construction projects, and were analyzed using principal component analysis. As a result, 6 interpretable principal components were extracted from the dataset: ‘unclear scope of work for multiple stakeholders in the definition and design of projects with new technology’, ‘the uncertainty in boundaries and communication relative to other complexity factors’, ‘unfamiliarity with other project participants’, ‘the multiplicity of stakeholders relative to the amount of cost pressure and execution risks’, ‘the relative multitude of engineered items’, and ‘the high-level program/project administration’. These complexity dimensions can help with understanding sources of project complexity and determining the skills, tools, and systems to effectively cope with the sources of project complexity. Additionally, the analysis results hint that organizational interfaces should be effectively managed to prevent project failure in construction projects, and therefore support the need for advanced interface management in complex projects.
Περιβαλλοντικός σχεδιασμός ορειβατικού καταλύματος σε προστατευόμενη περιοχή
Creators: name: Παπαϊωάννου, Αθηνά Φαίδωνος
Publisher: name: Aristotle University of Thessaloniki
Year: 2024
Subjects: Περιβαλλοντικός Σχεδιασμός
Καταφύγιο
Environmental Design
Refuge

description: Σκοπός της διατριβής ήταν η μελέτη των περιβαλλοντικών παραγόντων που συνθέτουν ένα πετυχημένο αρχιτεκτονικό σχέδιο ενός καταφυγίου σε προστατευόμενη περιοχή. Εξετάσαμε όλες τις περιβαλλοντικές συνθήκες που συνθέτουν ένα τέτοιο αρχιτεκτονικό πείραμα και την πιθανή τους εφαρμογή. Στη συνέχεια εμβαθύναμε στον αρχιτεκτονικό σχεδιασμό, στις ιδιότητες των υλικών, στις γεωμορφολογικές συνθήκες της περιοχής και τους τρόπους κατασκευής, πάντα με γνώμονα την ένταξη στο περιβάλλον και την ελάχιστη διατάραξή του. Επιπροσθέτως, σχεδιάσαμε με σκοπό την ανάδειξη του χαρακτήρα του τόπου κατασκευής και της παράδοσης της χώρας. Τέλος, Παρουσιάσαμε επιτυχημένα παραδείγματα υλοποιημένων κατασκευών με ηθική και σεβασμό προς το περιβάλλον και τον άνθρωπο.
description: The aim of the thesis was to study the environmental factors that make up a successful architectural design of a refuge in a protected area. We examined all the environmental conditions that make up such an architectural experiment and their possible application. We then delved into the architectural design, material properties, geomorphological conditions of the area and construction methods, always with a view to integration into the environment and minimal disturbance. In addition, we designed with a view to highlighting the character of the place of construction and the country's tradition. Finally, we presented successful examples of implemented constructions with ethics and respect for the environment and people.
On the Satisfiability of Local First-Order Logics with Data
Creators: name: Bollig, Benedikt
name: Sangnier, Arnaud
name: Stietel, Olivier
Publisher: name: arXiv
Year: 2023
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: We study first-order logic over unordered structures whose elements carry a finite number of data values from an infinite domain. Data values can be compared wrt.\ equality. As the satisfiability problem for this logic is undecidable in general, we introduce a family of local fragments. They restrict quantification to the neighbourhood of a given reference point that is bounded by some radius. Our first main result establishes decidability of the satisfiability problem for the local radius-1 fragment in presence of one "diagonal relation". On the other hand, extending the radius leads to undecidability. In a second part, we provide the precise decidability and complexity landscape of the satisfiability problem for the existential fragments of local logic, which are parameterized by the number of data values carried by each element and the radius of the considered neighbourhoods. Altogether, we draw a landscape of formalisms that are suitable for the specification of systems with data and open up new avenues for future research.
title: Canadian Bitcoin Ownership in 2023: Key Takeaways
Creators: name: Balutel, Daniela
name: Felt, Marie-Helene
name: Rusu, Doina
Publisher: name: Bank of Canada
publisherIdentifier: https://ror.org/05cc98565
publisherIdentifierScheme: ROR
Year: 2025

description: We provide an update on cryptoasset ownership in Canada using data from the Bitcoin Omnibus Survey (BTCOS) conducted in late 2023. Bitcoin ownership remained stable at around 10% in 2023 and continues to be concentrated among men, younger individuals and those with higher income and levels of education. The use of Bitcoin for payments remains limited, with most owners viewing it primarily as an investment. Despite growing awareness of alternative cryptocurrencies, Bitcoin remains the dominant holding among Canadians, with a median value of Can$500.
description: Nous faisons le point sur la possession de cryptoactifs au Canada en nous appuyant sur les données de l’enquête-omnibus sur le bitcoin menée à la fin de l’année 2023. La possession de bitcoins est restée stable à environ 10 % en 2023 et continue d’être concentrée chez les hommes, les plus jeunes et ceux dont le revenu et le niveau d’éducation sont plus élevés. L’utilisation du bitcoin pour les paiements reste limitée, la plupart des détenteurs le considérant avant tout comme un investissement. Même si les autres cryptomonnaies sont de plus en plus connues, le bitcoin demeure la plus détenue par les Canadiens, avec une valeur médiane de 500 dollars canadiens.
Sorafenib for advanced and refractory desmoid tumors
Creators: name: Deshpande, H.A.
name: Schwartz, L.H.
name: Riedel, R.F.
name: Milhem, M.M.
name: Tap, W.D.
name: Agaram, N.P.
name: Conry, R.M.
name: Ravi, V.
name: Gupta, A.A.
name: Mazaheri, Y.
name: Schwartz, G.K.
name: Horvat, N.
name: Wright, J.J.
name: Basch, E.
name: Pishvaian, M.J.
name: Mahoney, M.R.
name: Gounder, M.M.
name: Sabagh, T.
name: Attia, S.
name: Van Tine, B.A.
name: Dueck, A.C.
name: Maki, R.G.
name: Yamashita, R.
name: Lefkowitz, R.A.
name: Movva, S.
Publisher: name: Massachussetts Medical Society
Year: 2018

description: BACKGROUND Desmoid tumors (also referred to as aggressive fibromatosis) are connective tissue neoplasms that can arise in any anatomical location and infiltrate the mesentery, neurovascular structures, and visceral organs. There is no standard of care. METHODS In this double-blind, phase 3 trial, we randomly assigned 87 patients with progressive, symptomatic, or recurrent desmoid tumors to receive either sorafenib (400- mg tablet once daily) or matching placebo. Crossover to the sorafenib group was permitted for patients in the placebo group who had disease progression. The primary end point was investigator-assessed progression-free survival; rates of objective response and adverse events were also evaluated. RESULTS With a median follow-up of 27.2 months, the 2-year progression-free survival rate was 81% (95% confidence interval [CI], 69 to 96) in the sorafenib group and 36% (95% CI, 22 to 57) in the placebo group (hazard ratio for progression or death, 0.13; 95% CI, 0.05 to 0.31; P<0.001). Before crossover, the objective response rate was 33% (95% CI, 20 to 48) in the sorafenib group and 20% (95% CI, 8 to 38) in the placebo group. The median time to an objective response among patients who had a response was 9.6 months (interquartile range, 6.6 to 16.7) in the sorafenib group and 13.3 months (interquartile range, 11.2 to 31.1) in the placebo group. The objective responses are ongoing. Among patients who received sorafenib, the most frequently reported adverse events were grade 1 or 2 events of rash (73%), fatigue (67%), hypertension (55%), and diarrhea (51%). CONCLUSIONS Among patients with progressive, refractory, or symptomatic desmoid tumors, sorafenib significantly prolonged progression-free survival and induced durable responses.
Oncology in Transition
Creators: name: Basch, E.
name: Schrag, D.
Publisher: name: American Medical Association
Year: 2018

description: Contemporary challenges and changes in the field of oncology reflect and often magnify medicine more broadly. Morbidity and mortality are often substantial, treatment is expensive, and management is complex necessitating interdisciplinary coordination across every field of medicine. The recent emergence of immunotherapy and adoptive cellular therapy has generated tremendous excitement because these approaches can sometimes achieve cure or durable responses, even in the setting of advanced cancer.
Characterization of the photon emission statistics in nitrogen-vacancy centers
Creators: name: Panadero, Iván
name: Espinós, Hilario
name: Tsunaki, Lucas
name: Volkova, Kseniia
name: Tobalina, Ander
name: Casanova, Jorge
name: Acedo, Pablo
name: Naydenov, Boris
name: Puebla, Ricardo
name: Torrontegui, Erik
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We model and experimentally demonstrate the full time-dependent counting statistics of photons emitted by a single nitrogen-vacancy (NV) center in diamond under non-resonant laser excitation and resonant microwave control. A generalization of the quantum jump formalism for the seven electronic states involved in the fast intrinsic dynamics of an NV center provides a self-contained model that allows for the characterization of its emission and clarifies the relation between the quantum system internal states and the measurable detected photon counts. The model allows the elaboration of detection protocols to optimize the energy and time resources while maximizing the system sensitivity to magnetic-field measurements.
description: 11 pages, 8 figures
Supplementary document for Layer-dependent excitonic valley polarization properties in MoS2-WS2 heterostructures - 6099426.pdf
Creators: name: Li, Shaofei
name: Zheng, Haihong
name: Wu, Biao
name: Ding, Junnan
name: He, jun
name: Zongwen, Liu
name: Liu, Yanping
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
Content Validity of Anatomic Site-Specific Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) Item Sets for Assessment of Acute Symptomatic Toxicities in Radiation Oncology
Creators: name: Raldow, A.C.
name: Cook, R.R.
name: McCloskey, S.A.
name: Steinberg, M.L.
name: Sharif, J.
name: Sandler, K.A.
name: Basch, E.
name: Kupelian, P.A.
name: Mitchell, S.A.
Publisher: name: Elsevier Inc.
Year: 2018

description: Purpose: To improve assessment of symptomatic toxicity in cancer clinical trials and complement clinician-based toxicity reporting, the US National Cancer Institute developed a measurement system called the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE). The objective of this study was to examine the content validity of PRO-CTCAE in patients undergoing radiation therapy and to establish anatomic site-specific item sets for implementation in cancer research. Methods and Materials: Patients receiving radiation to the brain, head and neck, breast, thorax, abdomen, or pelvis were recruited during the final week of radiation. Participants described side effects qualitatively and completed anatomic site-specific checklists indicating the presence or absence of symptomatic toxicities drawn from the PRO-CTCAE library. Items endorsed by ≥20% of participants were selected for inclusion. Symptomatic toxicities described qualitatively were content analyzed and summarized. Symptomatic toxicities not reflected in the PRO-CTCAE item library were tabulated. Results: We conducted 389 interviews of patients receiving radiation to the brain (n = 46), head and neck (n = 69), breast (n = 134), thorax (n = 30), abdomen (n = 27), female pelvis (n = 36), or male pelvis (n = 47). Median age was 62 years; 62% were female. The 53 solicited PRO-CTCAE symptoms reflected all reported radiation-induced toxicities with the exception of phlegm/mucus production and mouth/throat pain with swallowing in patients receiving head and neck radiation, eye dryness/irritation in patients undergoing brain radiation, and obstructive urinary symptoms in men receiving pelvic radiation. The PRO-CTCAE items “skin burns” and “pain” require greater specificity to adequately reflect toxicities experienced during radiation. Conclusions: PRO-CTCAE demonstrates strong content validity as a measure of symptomatic toxicities in patients receiving radiation. These results provide empirical support for the definition of site-specific PRO-CTCAE item sets to assess the symptomatic toxicities of radiation therapy. The site-specific PRO-CTCAE item sets developed herein are currently being deployed in our department via an electronic platform to capture treatment-related toxicity.