cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On the Joint Evolution Problem for a Scalar Field and its Singularity
Creators: name: Agashe, Aditya
name: Lee, Ethan
name: Tahvildar-Zadeh, A. Shadi
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 78A35, 35A21, 70S10

description: In the classical electrodynamics of point charges in vacuum, the electromagnetic field, and therefore the Lorentz force, is ill-defined at the locations of the charges. Kiessling resolved this problem by using the momentum balance between the field and the particles, extracting an equation for the force that is well-defined where the charges are located, so long as the field momentum density is locally integrable in a neighborhood of the charges.
 In this paper, we examine the effects of such a force by analyzing a simplified model in one space dimension. We study the joint evolution of a massless scalar field together with its singularity, which we identify with the trajectory of a particle. The static solution arises in the presence of no incoming radiation, in which case the particle remains at rest forever. We will prove the stability of the static solution for particles with positive bare mass by showing that a pulse of incoming radiation that is compactly supported away from the point charge will result in the particle eventually coming back to rest. We will also prove the nonlinear instability of the static solution for particles with negative bare mass by showing that an incoming radiation with arbitrarily small amplitude will cause the particle to reach the speed of light in finite time. We conclude by discussing modifications to this simple model that could make it more realistic.
description: 22 pages, 5 figures
Mass number and excitation energy dependence of the $Θ_{eff}/Θ_{rig}$ parameter of the spin cut-off factor in the formation of an isomeric pair
Creators: name: Sudár, S.
name: Qaim, S. M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Nuclear Theory (nucl-th)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The $Θ_{eff}/Θ_{rig}$ parameter of the spin distribution of the level density was determined for 61 nuclei covering the mass range of 44 to 200. The experimental isomeric cross-section ratios for 25 isomeric pairs were compared with the model calculation to find the best fit to the experimental data. The model calculations were carried out with the TALYS code using the BSFG model for the level density. The reduced $χ^2$ values were calculated to describe the deviation of the experimental data from the model calculation. An $η_d $ was introduced calculating the $Θ_{eff}/Θ_{rig}$ value from the low energy discrete levels of the nucleus. The $η/η_d $ values seem to be independent of the mass number, their average value near to one. The $η/η_d $ values also seem to be independent of the average excitation energy in the continuum, indicating that $η$ is independent of the excitation energy. The mass number and (N-Z) dependence of the $η$ values were studied. The $η$ values for the nuclei with odd mass number show an exponential decrease as a function of A or (N-Z). The $η$ values for the odd-odd type of nuclei appear to be constant, near one, up to the mass number 110 or (N-Z) of 13. Above these values, the $η$ values show exponential decrease. The $η$ values for even-even type nuclei decrease exponentially up to A equal to 142 or (N-Z) equal to 20. The values are lower than those for the nearby odd-odd type nuclei. The $η$ values increase for nuclei with A between 142 and 156 and (N-Z) between 20 and 28, and they finally reach the value of odd-odd type systematics.
description: 67+3 pages, 52+2 figures. Calculations with EMPIRE have been added to Section IV.3
Intercensal updating using structure-preserving methods and satellite imagery
Creators: name: Koebe, Till
name: Arias-Salazar, Alejandra
name: Rojas-Perilla, Natalia
name: Schmid, Timo
Publisher: name: arXiv
Year: 2021
Subjects: subject: Applications (stat.AP)
subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: Censuses are fundamental building blocks of most modern-day societies, yet collected every ten years at best. We propose an extension of the widely popular census updating technique Structure Preserving Estimation by incorporating auxiliary information in order to take ongoing subnational population shifts into account. We apply our method by incorporating satellite imagery as additional source to derive annual small-area updates of multidimensional poverty indicators from 2013 to 2020 for a population at risk: female-headed households in Senegal. We evaluate the performance of our proposal using data from two different census periods.
Additional file 6: of Comparing miRNA structure of mirtrons and non-mirtrons
Creators: name: Titov, Igor
name: Vorozheykin, Pavel
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology

description: The branchpoint locations across mirtrons and introns. (DOCX 31Â kb)
Effects of counter-rotating-wave terms on the non-Markovianity in quantum open systems
Creators: name: Wu, Wei
name: Liu, Maoxin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the effect of counter-rotating-wave terms on the non-Markovianity in quantum open systems by employing the hierarchical equations of motion in the framework of the non-Markovian quantum state diffusion approach. As illustrative examples, the non-Markovian memory effect of a qubit embedded in a bosonic and a fermionic environment at zero temperature are analyzed. It is found that the counter-rotating-wave terms are able to enhance the observed non-Markovianity no matter the environment is composed of bosons or fermions. This result suggests that the rotating-wave approximation may inevitably reduce the non-Markovianity in quantum open systems. Moreover, we find that the modification of the non-Markovianity due to the different statistical properties of environmental modes becomes larger with the increase of the system-environment coupling strength.
Precision Nucleon Charges and Form Factors Using 2+1-flavor Lattice QCD
Creators: name: Park, Sungwoo
name: Gupta, Rajan
name: Yoon, Boram
name: Mondal, Santanu
name: Bhattacharya, Tanmoy
name: Jang, Yong-Chull
name: Joó, Bálint
name: Winter, Frank
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present high statistics results for the isovector nucleon charges and form factors using seven ensembles of 2+1-flavor Wilson-clover fermions. The axial and pseudoscalar form factors obtained on each ensemble satisfy the PCAC relation once the lowest energy $Nπ$ excited state is included in the spectral decomposition of the correlation functions used for extracting the ground state matrix elements. Similarly, we find evidence that the $Nππ$ excited state contributes to the correlation functions with the vector current, consistent with the vector meson dominance model. The resulting form factors are consistent with the Kelly parameterization of the experimental electric and magnetic data. Our final estimates for the isovector charges are $g_{A}^{u-d} = 1.31(06)(05)_{sys}$, $g_{S}^{u-d} = 1.06(10)(06)_{sys}$, and $g_{T}^{u-d} = 0.95(05)(02)_{sys}$, where the first error is the overall analysis uncertainty and the second is an additional combined systematic uncertainty. The form factors yield: (i) the axial charge radius squared, ${\langle r_A^2 \rangle}^{u-d}=0.428(53)(30)_{sys}\ {\rm fm}^2$, (ii) the induced pseudoscalar charge, $g_P^\ast=7.9(7)(9)_{sys}$, (iii) the pion-nucleon coupling $g_{π{\rm NN}} = 12.4(1.2)$, (iv) the electric charge radius squared, ${\langle r_E^2 \rangle}^{u-d} = 0.85(12)(19)_{sys} \ {\rm fm}^2$, (v) the magnetic charge radius squared, ${\langle r_M^2 \rangle}^{u-d} = 0.71(19)(23)_{\rm sys} \ {\rm fm}^2$, and (vi) the magnetic moment $μ^{u-d} = 4.15(22)(10)_{\rm sys}$. All our results are consistent with phenomenological/experimental values but with larger errors. Lastly, we present a Padé parameterization of the axial, electric and magnetic form factors over the range $0.04< Q^2 <1$ GeV${}^2$ for phenomenological studies.
description: 84 pages, 39 figures, 24 tables. This is the version published by PRD
Light-amplified Landau-Zener conductivity in gapped graphene monolayers: a simulacrum of photo-catalyzed vacuum instability
Creators: name: Villalba-Chávez, Selym
name: Mathiak, Oliver
name: Egger, Reinhold
name: Müller, Carsten
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Interband transitions of electrons in a gapped graphene monolayer are highly stimulated near the Fermi surface when a high-frequency electric wave of weak intensity and a strong constant electric field are superposed in the plane of the flake. We consider this phenomenon equivalent to the Franz-Keldysh effect, paying particular attention to the regime where the photon energy linked to the fast-oscillating field is just below the graphene gap, so that the quantum transitions still occur through tunneling effects while being facilitated by the one-photon absorption channel. In the considered parameter regime the photo-catalyzed current linked to the described setup is shown to exceed the one driven by the strong field solely by several orders of magnitude. Conditions to relieve the impact of the field's finite extension are discussed, and a formula for the residual current density is derived. The robustness of our assessment supports the viability of detecting this phenomenon in graphene, thus providing a simulation of the dynamically-assisted Schwinger mechanism in QED.
description: 16 pages, 8 figures, to appear in PRD
Priming Older Adults and People with Mild to Moderate Alzheimer’s Disease Problem-solving with False Memories
Creators: name: Akhtar, Shazia
Publisher: name: UH Research Archive
Year: 2020
Subjects: Alzheimer's

description: These data are from two Experiments investigating whether older adult controls (OACs) and people with mild and moderate Alzheimer’s disease (AD) benefit from false memory priming effects in subsequent problem-solving tasks. In addition, we examined latency measures in the recognition phase. The data are responses to a recognition task and then a subsequent problem solving task (CRAT task Experiment 1 and Analogical Problem Solving task Experiment 2). Details of the task are provided in DRM and CRAT lists for Experiment 1.pdf and Analogies and DRM lists for Experiment 2.pdf.
Additional file 2: Table S2. of Consequences of early life stress on genomic landscape of H3K4me3 in prefrontal cortex of adult mice
Creators: name: Ershov, Nikita
name: Bondar, Natalya
name: Lepeshko, Arina
name: Reshetnikov, Vasiliy
name: Ryabushkina, Julia
name: Merkulova, Tatiana
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: Primers and Taqman probes for real time PCR (DOCX 43Â kb)
title: ADCO, Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Cart. 168 (11 H 66), f. 0086r
Creators: name: de la Côte d'Or, Archives départementales
name: CG21/F.PETOT/2010
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 168 (11 H 66), f. 0086r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 168 (11 H 66), f. 0086r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
Optimal local law and central limit theorem for $β$-ensembles
Creators: name: Bourgade, Paul
name: Mody, Krishnan
name: Pain, Michel
Publisher: name: arXiv
Year: 2021
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: In the setting of generic $β$-ensembles, we use the loop equation hierarchy to prove a local law with optimal error up to a constant, valid on any scale including microscopic. This local law has the following consequences. (i) The optimal rigidity scale of the ordered particles is of order $(\log N)/N$ in the bulk of the spectrum. (ii) Fluctuations of the particles satisfy a central limit theorem with covariance corresponding to a logarithmically correlated field; in particular each particle in the bulk fluctuates on scale $\sqrt{\log N}/N$. (iii) The logarithm of the electric potential also satisfies a logarithmically correlated central limit theorem. Contrary to much progress on random matrix universality, these results do not proceed by comparison. Indeed, they are new for the Gaussian $β$-ensembles. By comparison techniques, (ii) and (iii) also hold for Wigner matrices.
description: 47 pages, to appear in Comm. Math. Phys
A Beam Monitor for Ion Beam Therapy based on HV-CMOS Pixel Detectors
Creators: name: Balzer, Matthias
name: Dierlamm, Alexander
name: Ehrler, Felix
name: Husemann, Ulrich
name: Koppenhöfer, Roland
name: Perić, Ivan
name: Pittermann, Martin
name: Topko, Bogdan
name: Weber, Alena
name: Brons, Stephan
name: Debus, Jürgen
name: Grau, Nicole
name: Hansmann, Thomas
name: Jäkel, Oliver
name: Klüter, Sebastian
name: Naumann, Jakob
Publisher: name: arXiv
Year: 2022
Subjects: subject: Medical Physics (physics.med-ph)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: Particle therapy is a well established clinical treatment of tumors. More than one hundred particle therapy centers are in operation world wide. The advantage of using hadrons like protons or carbon ions as particles for tumor irradiation is the distinct peak in the depth dependent energy deposition, which can be exploited to accurately deposit dose in the tumor cells. To guarantee this, high accuracy of monitoring and control of the particle beam is of utmost importance. Before the particle beam enters the patient, it traverses a monitoring system which has to give fast feedback to the beam control system on position and dose rate of the beam while minimally interacting with the beam. The multi-wire chambers mostly used as beam position monitor have their limitations when fast response time is required (drift time). Future developments like MRI-guided ion beam therapy pose additional challenges for the beam monitoring system like tolerance of magnetic fields and acoustic noise (vibrations). Solid-state detectors promise to overcome these limitations and the higher resolution they offer can create additional benefits. This article presents the evaluation of an HV-CMOS detector for beam monitoring, provides results from feasibility studies in a therapeutic beam and summarizes the concepts towards the final large-scale assembly and readout system.
description: Submitted to Instruments (MDPI)
Reply to Comment on "Nonlinear quantum effects in electromagnetic radiation of a vortex electron" by A. Karnieli, R. Remez, I. Kaminer, et al
Creators: name: Karlovets, D. V.
name: Pupasov-Maksimov, A. M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We argue that while the experiment of Remez et al. is interesting and its conclusions may well be correct, the observed lack of dependence of the measured distributions on the electron's transverse coherence length should have been expected for the parameters chosen. This is because for Smith-Purcell radiation it is the coherence length of a virtual photon that plays a role of the radiation formation width and not the entire electron's coherence length that can well be orders of magnitude larger. This is a common feature for all the radiation processes in which a photon is emitted not directly by the electron, which can be delocalized in space, but rather by a much better localized atom or a conduction electron on a surface. Therefore, in our opinion the results of Remez et al. cannot rule out the alternative hypothesis of the delocalized charge. The question, mainly addressed in the comment by Karnieli et al., of whether the measurements were performed in the wave zone or not is interesting but secondary. We emphasize that the measured distributions are unusually wide and neither the original paper nor the recent comment fully discusses and rules out all alternative hypotheses that could have led to the same distributions. On the contrary, there exists a family of classical effects that could also have resulted in the measured distributions and that were neither discussed nor even mentioned by the authors. Such alternative hypotheses include (i) effects of the beam sizes, of its angular divergence, of the temporal coherence of the process, and (ii) influence of the grating shape and of its material. Finally, we propose to repeat the experiment and to measure diffraction radiation from a thin metallic semi-plane or Compton emission in a laser pulse. In these cases, the classical effects play a much smaller role and the results of such measurements would have higher credibility.
description: 12 pages, 2 figures, additional comments
Uncovering the Role of the Epithelial-Mesenchymal Transition in Ovarian Cancer Immunogenicity
Creators: name: Yakubovich, Edward
Publisher: name: Université d'Ottawa | University of Ottawa
Year: 2024
Subjects: ovarian cancer
bioinformatics
epithelial-mesenchymal transition
cancer
EMT

description: Cancer cells often metastasize by undergoing an epithelial-mesenchymal transition (EMT). While undergoing EMT, epithelial cells lose defining characteristics, such as stable cell-cell junctions, and gain the ability to migrate and invade through extracellular matrices. In addition to these changes in characteristics, mesenchymal cells gain the ability to better regulate the immune system around them. Immune regulation by mesenchymal cells in cancer has been a topic of extensive study and has recently started receiving focus in ovarian cancer. Combined with the emergence of advanced single-cell sequencing techniques, there is now great potential in unraveling the interactions underlying immune regulation by mesenchymal cells and the contribution of the EMT to the phenomenon of immunosuppression in cancer. Here, I present my studies applying a combined approach of single-cell transcriptomics (scRNA-seq) and lab-based techniques to characterize the relationship between the EMT and immune regulation in ovarian cancer. First, by characterizing human ovarian tumors and murine ovarian cancer models I identified that mesenchymal cells secrete chemokines and interleukins into their environment such as CCL2, CCL5, and IL1A. The primary immunosuppressive factor secreted by mesenchymal cells against NK cells was determined to be TGF-β1. I also discovered a possible link between infiltration of immune cells into the tumor microenvironment (TME) and EMT where greater numbers of mesenchymal cells in the TME correlated with a greater number and variety of immune cells in both human ovarian tumors and murine ovarian cancer models. Second, by cell-cell communication analysis of scRNA-seq data, I discovered that LGALS3 expressed by mesenchymal cells may exhaust CD8⁺ T-cells through the LAG3 receptor in human ovarian cancers. Finally, I uncovered links between EMT and the antigen presentation machinery of ovarian cancer cells where higher expression levels of major histocompatibility complex I (MHC I) positively correlated with the presence of mesenchymal cells in the TME. This work further expands the knowledge base of EMT and immunosuppression in ovarian cancer and can be used to inform researchers and clinicians on new targets and mechanisms for future research and therapy, such as targeting the LGALS3-LAG3 axis in ovarian cancer to relieve exhaustion of T-cells.
Bioactive Eudesmane sesquiterpenes from Artabotrys hongkongensis Hance
Creators: name: Wen, Qing
name: Liu, Yan-Ping
name: Yan, Gui
name: Yang, Shuo
name: Hu, Shi
name: Hua, Jing
name: Yin, Wen-Qing
name: Chen, Guang-Ying
name: Fu, Yan-Hui
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: A new naturally occurring trinoreudesmane sesquiterpene, artahongkongol A (1), together with seven known eudesmane sesquiterpenes (2−8), was isolated from the stems and leaves of Artabotrys hongkongensis Hance. Among them, 1 is a rare trinoreudesmane sesquiterpene containing 12 carbon atoms on the carbon skeleton. All known compounds (2−8) were isolated from the genus Artabotrys for the first time. The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons with data reported in the literature. All isolated compounds were evaluated for their cytotoxicities against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480 in vitro. Compounds 1−8 showed significant inhibitory effects against various human cancer cell lines with IC50 values ranging from 0.57 to 15.68 μM.
MOESM1 of Characterization and engineering of a dual-function diacylglycerol acyltransferase in the oleaginous marine diatom Phaeodactylum tricornutum
Creators: name: Yulin Cui
name: Jialin Zhao
name: Yinchu Wang
name: Qin, Song
name: Yandu Lu
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1. PtWS DGAT cDNA sequence.
Accelerated Nonnegative Tensor Completion via Integer Programming
Creators: name: Pan, Wenhao
name: Aswani, Anil
name: Chen, Chen
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Optimization and Control (math.OC)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: The problem of tensor completion has applications in healthcare, computer vision, and other domains. However, past approaches to tensor completion have faced a tension in that they either have polynomial-time computation but require exponentially more samples than the information-theoretic rate, or they use fewer samples but require solving NP-hard problems for which there are no known practical algorithms. A recent approach, based on integer programming, resolves this tension for nonnegative tensor completion. It achieves the information-theoretic sample complexity rate and deploys the Blended Conditional Gradients algorithm, which requires a linear (in numerical tolerance) number of oracle steps to converge to the global optimum. The tradeoff in this approach is that, in the worst case, the oracle step requires solving an integer linear program. Despite this theoretical limitation, numerical experiments show that this algorithm can, on certain instances, scale up to 100 million entries while running on a personal computer. The goal of this paper is to further enhance this algorithm, with the intention to expand both the breadth and scale of instances that can be solved. We explore several variants that can maintain the same theoretical guarantees as the algorithm, but offer potentially faster computation. We consider different data structures, acceleration of gradient descent steps, and the use of the Blended Pairwise Conditional Gradients algorithm. We describe the original approach and these variants, and conduct numerical experiments in order to explore various tradeoffs in these algorithmic design choices.
description: 23 pages. Abstract accepted by Frontiers in Applied Mathematics and Statistics. Full manuscript submitted and under review
Additional file 4: of Comparing miRNA structure of mirtrons and non-mirtrons
Creators: name: Titov, Igor
name: Vorozheykin, Pavel
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Overhang length dependence are robust against the overhang definition. (DOCX 62Â kb)
Molecular Assembly Lines in Active Droplets
Creators: name: Harmon, Tyler S.
name: Jülicher, Frank
Publisher: name: arXiv
Year: 2021
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Large protein complexes are assembled from protein subunits to form a specific structure. In our theoretic work, we propose that assembly into the correct structure could be reliably achieved through an assembly line with a specific sequence of assembly steps. Using droplet interfaces to position compartment boundaries, we show that an assembly line can be self organized by active droplets. As a consequence, assembly steps can be arranged spatially so that a specific order of assembly is achieved and incorrect assembly is strongly suppressed.
Impedance Spectroscopy to Measure Placental Barrier Integrity
Creators: name: Saadé, Karim
Publisher: name: Université d'Ottawa | University of Ottawa
Year: 2024
Subjects: Bioimpedance spectroscopy
Placenta-on-a-chip
Fusion index
Transepithelial/transendothelial electrical resistance (TEER)
Electrical capacitance

description: Various placenta models have been developed, including in-vivo, ex-vivo, and in-vitro approaches, aiming to provide a better understanding of the placental barrier and its interactions with medicinal drugs during pregnancy. The in-vitro model and specifically the placenta-on-a-chip models have shown significant promises as an alternative to conventional in-vitro, in-vivo, and ex-vivo models for investigating the fetal exposure to drugs administered to pregnant mothers. The use of non-invasive techniques allows for continuous monitoring of barrier integrity without damaging the cells. One technique allowing such monitoring is called bioimpedance spectroscopy to measure the transepithelial/transendothelial electrical resistance (TEER) and the electrical capacitance of cell membrane. The aim of this thesis is to (i) Design and optimize a low cost, effective and reproducible impedance measuring device to assess the placenta barrier permeability changes; (ii) Measure and track electrical properties of a monolayer of epithelial cells to validate the setup; (iii) Capture and process syncytialisation data from TEER to correlate with the cell fusion index obtained from immunofluorescence imaging and (iv) Propose a Lab-on-a-Chip (LOC) design to mimic a physiological placental barrier in-vitro. We show that the developed impedance spectroscopy system is suitable to measure and track barrier permeability. The measurements confirmed the formation of a confluent monolayer at Day 4. The electrical resistance tripled for treated samples showing the formation of a confluent layer. This resistance remained constant for treated samples reflecting the intact cell barrier and retention of the barrier's integrity over the next 3 days. The resistance of the untreated samples remained in an increasing linear trend due to its lack of fusion and multiple layer formation. The measurements show that, at Day 4, the electrical capacitance of the cells decreases for treated sample as opposed to untreated samples. This reflects that the surface area of the BeWo b30 cells decreases when the samples were treated with forskolin.
Enhanced Light-Matter Interaction in Two-Dimensional Transition Metal Dichalcogenides
Creators: name: Huang, Lujun
name: Krasnok, Alex
name: Alu, Andrea
name: Yu, Yiling
name: Neshev, Dragomir
name: Miroshnichenko, Andrey E
Publisher: name: arXiv
Year: 2021
Subjects: subject: Optics (physics.optics)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Two dimensional (2D) transition metal dichalcogenide (TMDC) materials, such as MoS2, WS2, MoSe2, and WSe2, have received extensive attention in the past decade due to their extraordinary physical properties. The unique properties make them become ideal materials for various electronic, photonic and optoelectronic devices. However, their performance is limited by the relatively weak light-matter interactions due to their atomically thin form factor. Resonant nanophotonic structures provide a viable way to address this issue and enhance light-matter interactions in 2D TMDCs. Here, we provide an overview of this research area, showcasing relevant applications, including exotic light emission, absorption and scattering features. We start by overviewing the concept of excitons in 1L-TMDC and the fundamental theory of cavity-enhanced emission, followed by a discussion on the recent progress of enhanced light emission, strong coupling and valleytronics. The atomically thin nature of 1L-TMDC enables a broad range of ways to tune its electric and optical properties. Thus, we continue by reviewing advances in TMDC-based tunable photonic devices. Next, we survey the recent progress in enhanced light absorption over narrow and broad bandwidths using 1L or few-layer TMDCs, and their applications for photovoltaics and photodetectors. We also review recent efforts of engineering light scattering, e.g., inducing Fano resonances, wavefront engineering in 1L or few-layer TMDCs by either integrating resonant structures, such as plasmonic/Mie resonant metasurfaces, or directly patterning monolayer/few layers TMDCs. We then overview the intriguing physical properties of different types of van der Waals heterostructures, and their applications in optoelectronic and photonic devices. Finally, we draw our opinion on potential opportunities and challenges in this rapidly developing field of research.
description: 101 pages, 25 figures
Dirac-Witten Operators and the Kastler-Kalau-Walze type theorem for manifolds with boundary
Creators: name: Wu, Tong
name: Wang, Jian
name: Wang, Yong
Publisher: name: arXiv
Year: 2021
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: In this paper, we obtain two Lichnerowicz type formulas for the Dirac-Witten operators. And we give the proof of Kastler-Kalau-Walze type theorems for the Dirac-Witten operators on 4-dimensional and 6- dimensional compact manifolds with (resp.without) boundary
Acceleration and suppression of banana-shaped-protein-induced tubulation by addition of small membrane inclusions of isotropic spontaneous curvatures
Creators: name: Noguchi, Hiroshi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: The membrane tubulation induced by banana-shaped protein rods is investigated by using coarse-grained meshless membrane simulations. It is found that the tubulation is promoted by laterally isotropic membrane inclusions that generate the same sign of spontaneous curvature as the adsorbed protein rods. The inclusions are concentrated in the tubules and reduce the bending energy of the tip of the tubules. On the other hand, the inclusions with an opposite curvature suppress the tubulation by percolated-network formation at a high protein-rod density while they induce a spherical membrane bud at a low rod density. When equal amounts of the two types of inclusions (with positive and negative curvatures) are added, their effects cancel each other for the first short period but later the tubulation is slowly accelerated. A positive surface tension suppresses the tubulation. Out results suggest that the cooperation of scaffolding of BAR (Bin/Amphiphysin/Rvs) domains and isotropic membrane inclusions is important for the tubulation.
description: 9 pages, 7 figures
Additional file 1: of Systemic autoinflammation with intractable epilepsy managed with interleukin-1 blockade
Creators: name: DeSena, Allen
name: Do, Thuy
name: Schulert, Grant
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplemental methods; TablesÂ S1â S4. Supplemental methods on gene expression analysis; tables of mapped reads and coverage, genes with >â 2-fold difference between pre-treatment sample and controls, and Rap1 pathway genes. (DOCX 51 kb)
Källén-Lehmann Spectral Representation of the Scalar SU(2) Glueball
Creators: name: Dudal, David
name: Oliveira, Orlando
name: Roelfs, Martin
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The estimation of the Källén-Lehmann spectral density from gauge invariant lattice QCD two point correlation functions is proposed, and explored via an appropriate inversion method. As proof of concept the SU(2) glueball spectrum for the quantum numbers $J^{PC} = 0^{++}$ is investigated for various values of the lattice spacing. The spectral density and the glueball spectrum are estimated using the published data of arXiv:1910.07756. Our estimates for the ground state mass are in good agreement with the traditional approach published therein, which is based on the large time exponential behaviour of the correlation functions. Furthermore, the spectral density also contains hints of excites states in the spectrum.
description: 17 pages, 9 figures
Additional file 2: of Correction to: Association between inflammation and systolic blood pressure in RA compared to patients without RA
Creators: name: Yu, Zhi
name: Kim, Seoyoung
name: Vanni, Kathleen
name: Huang, Jie
name: Desai, Rishi
name: Murphy, Shawn
name: Solomon, Daniel
name: Liao, Katherine
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology

description: Figure S2. The relationship between C-reactive protein levels (CRP) and diastolic blood pressure (A), pulse pressure (B), and mean arterial pressure (C) with 95% confidence intervals, in the non-RA outpatient population and the general population (NHANES). RA, rheumatoid arthritis; NHANES, National Health and Nutrition Examination Survey. (PDF 111 kb)
Malaria Parasitic Detection using a New Deep Boosted and Ensemble Learning Framework
Creators: name: Khan, Saddam Hussain
name: Alahmadi, Tahani Jaser
Publisher: name: arXiv
Year: 2022
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Malaria is a potentially fatal plasmodium parasite injected by female anopheles mosquitoes that infect red blood cells and millions worldwide yearly. However, specialists' manual screening in clinical practice is laborious and prone to error. Therefore, a novel Deep Boosted and Ensemble Learning (DBEL) framework, comprising the stacking of new Boosted-BR-STM convolutional neural networks (CNN) and the ensemble ML classifiers, is developed to screen malaria parasite images. The proposed Boosted-BR-STM is based on a new dilated-convolutional block-based split transform merge (STM) and feature-map Squeezing-Boosting (SB) ideas. Moreover, the new STM block uses regional and boundary operations to learn the malaria parasite's homogeneity, heterogeneity, and boundary with patterns. Furthermore, the diverse boosted channels are attained by employing Transfer Learning-based new feature-map SB in STM blocks at the abstract, medium, and conclusion levels to learn minute intensity and texture variation of the parasitic pattern. The proposed DBEL framework implicates the stacking of prominent and diverse boosted channels and provides the generated discriminative features of the developed Boosted-BR-STM to the ensemble of ML classifiers. The proposed framework improves the discrimination ability and generalization of ensemble learning. Moreover, the deep feature spaces of the developed Boosted-BR-STM and customized CNNs are fed into ML classifiers for comparative analysis. The proposed DBEL framework outperforms the existing techniques on the NIH malaria dataset that are enhanced using discrete wavelet transform to enrich feature space. The proposed DBEL framework achieved Accuracy (98.50%), Sensitivity (0.9920), F-score (0.9850), and AUC (0.997), which suggest it to be utilized for malaria parasite screening.
description: 26 pages, 10 figures, 9 Tables
Searching New Particles at Neutrino Telescopes with Quantum-Gravitational Decoherence
Creators: name: Hellmann, Dominik
name: Päs, Heinrich
name: Rani, Erika
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss the interplay of wave packet decoherence and decoherence induced by quantum gravity via interactions with spacetime foam for high energy astrophysical neutrinos. In this context we point out a compelling consequence of the expectation that quantum gravity should break global symmetries, namely that quantum-gravity induced decoherence may not only be the most sensitive probe for quantum properties of spacetime, but also can provide both a powerful tool for the search for new particles, including totally decoupled backgrounds interacting only gravitationally, and at the same time a window into the intricacies of black hole information processing.
description: 25 pages, 4 figures, version to be published in Physical Review D
Isotropic Buchdahl's relativistic fluid sphere within $f(R,\,T)$ gravity
Creators: name: Bhar, Piyali
name: Rej, Pramit
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The aim of the research is to look into a new solution for isotropic compact stars in the context of the $f(R,\,T)$ theory of gravity. We used the Buchdahl [H.A. Buchdahl, Phys. Rev. {\bf 116} (1959) 1027] metric potentials as input to deal with the field equations in the $f(R,\,T)$ framework. For different values of the coupling parameter $χ$, graphical representation of the model parameters have been shown to canvass the analytical results more clearly. Interestingly, we have proven that for $χ=0$, the standard General Relativity (GR) results can be recovered. A comparison of our obtained solutions with the GR results is also discussed. To study the effect of the coupling parameter $χ$, the numerical values of the different physical variables have been tabulated for the values of the coupling parameter $χ=0,\,0.25,\,0.5,\,0.75,1,\,1.25$. We used the compact stars candidate LMC X-4 with mass$=(1.04 \pm 0.09)M_{\odot}$; Radius $= 8.301_{-0.2}^{+0.2}$ km. respectively, for graphical analysis. To determine the physical acceptability of the model, we looked into the necessary physical properties such as energy conditions, causality, hydrostatic equilibrium, and pressure-density ratio etc. and found that our system satisfies all of these criteria, indicating that the model is physically reasonable.
description: 15 Pages, 9 Figures ; Accepted for publication in New Astronomy on 14.12.2022 (Manuscript Number: NEWAST-D-22-00280R1). arXiv admin note: text overlap with arXiv:2112.07581
Additional file 4: of GestationaL Obesity Weight management: Implementation of National Guidelines (GLOWING): a pilot cluster randomised controlled trial of a guideline implementation intervention for the management of maternal obesity by midwives
Creators: name: Heslehurst, Nicola
name: Rankin, Judith
name: McParlin, Catherine
name: Sniehotta, Falko
name: Howel, Denise
name: Rice, Stephen
name: McColl, Elaine
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Computational Biology

description: GLOWING participant information sheets and consent forms for midwives (questionnaire data collection, participating in the intervention training days, focus groups) and pregnant women (baseline data collection, outcome data collection, interviews). (DOCX 218Â kb)
Lettre de Jean-Guillaume Bruguière à Jean-François Séguier, 1776-02-10
Creators: name: Bruguière, Jean-Guillaume
name: Jean-Guillaume Bruguière
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Botanique
Santé

description: [transcription] Monsieur,

Je me reproche d'avoir resté si longtemps à vous remercier de l'obligeante attention que vous avez pour moi, en me communiquant les livres précieux de votre bibliothèque. J'hésitais parce que j'avais encore de nouvelles pierres à vous faire et que je craignais pouvoir être taxé d'indiscrétion n'ayant pas l'honneur d'être connu de vous. Messieurs Lamoreux (Amoreux), Gouan et Cusson m'ont rassuré aussi, Monsieur, si ma demande est hasardeuse, veuillez de grâce ne pas me rendre seul responsable du blâme.

Je travaille actuellement à mettre en ordre quelques plantes que j'ai apportées d'un voyage que j'ai fait au cap de Bonne-Espérance et à Madagascar. La saison et les circonstances ne me permirent pas de rendre mes recherches botaniques aussi intéressantes qu'on devait naturellement les attendre d'un homme qui a eu le bonheur de mettre le pied dans des pays si riches, néanmoins les [fol. 392 v] plantes que j'en rapporte sont plus que suffisantes pour embarrasser un jeune botaniste et c'est [pour] me fixer sur certaines d'elles que je m'estimerais heureux de recevoir vos conseils, vos travaux, votre expérience et votre autorité serviraient à me rassurer et à me remettre dans la route dont je sais qu'il est quelquefois bien difficile de ne pas s'écarter. Si vous m'accordez ma prière, il ne me restera plus qu'à vous faire agréer l'estime sincère et le respect profond avec lesquels j'ai l'honneur d'être,

Monsieur,

Votre très humble et très obéissant serviteur

Bruguière, médecin.

A Montpellier, ce 10 février 1776

Vis-à-vis l'église des R. Pères de la Mercy.
description: [personnes citées] Antoine Gouan, Pierre Cusson, Pierre Joseph Amoreux
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 138_18, fol. 392
description: Source: ark:/12148/btv1b10015174r
Enabling Self-aware Smart Buildings by Augmented Reality
Creators: name: Aftab, Muhammad
name: Chau, Sid Chi-Kin
name: Khonji, Majid
Publisher: name: arXiv
Year: 2017
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Conventional HVAC control systems are usually incognizant of the physical structures and materials of buildings. These systems merely follow pre-set HVAC control logic based on abstract building thermal response models, which are rough approximations to true physical models, ignoring dynamic spatial variations in built environments. To enable more accurate and responsive HVAC control, this paper introduces the notion of "self-aware" smart buildings, such that buildings are able to explicitly construct physical models of themselves (e.g., incorporating building structures and materials, and thermal flow dynamics). The question is how to enable self-aware buildings that automatically acquire dynamic knowledge of themselves. This paper presents a novel approach using "augmented reality". The extensive user-environment interactions in augmented reality not only can provide intuitive user interfaces for building systems, but also can capture the physical structures and possibly materials of buildings accurately to enable real-time building simulation and control. This paper presents a building system prototype incorporating augmented reality, and discusses its applications.
description: This paper appears in ACM International Conference on Future Energy Systems (e-Energy), 2018
Competing correlated states around the zero field Wigner crystallization transition of electrons in two-dimensions
Creators: name: Falson, Joseph
name: Sodemann, Inti
name: Skinner, Brian
name: Tabrea, Daniela
name: Kozuka, Yusuke
name: Tsukazaki, Atsushi
name: Kawasaki, Masashi
name: von Klitzing, Klaus
name: Smet, Jurgen H
Publisher: name: arXiv
Year: 2021
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The competition between kinetic energy and Coulomb interactions in electronic systems can lead to complex many-body ground states with competing superconducting, charge density wave, and magnetic orders. Here we study the low temperature phases of a strongly interacting zinc-oxide-based high mobility two dimensional electron system that displays a tunable metal-insulator transition. Through a comprehensive analysis of the dependence of electronic transport on temperature, carrier density, in-plane and perpendicular magnetic fields, and voltage bias, we provide evidence for the existence of competing correlated metallic and insulating states with varying degrees of spin polarization. Our system features an unprecedented level of agreement with the state-of-the-art Quantum Monte Carlo phase diagram of the ideal jellium model, including a Wigner crystallization transition at a value of the interaction parameter $r_s\sim 30$ and the absence of a pure Stoner transition. In-plane field dependence of transport reveals a new low temperature state with partial spin polarization separating the spin unpolarized metal and the Wigner crystal, which we examine against possible theoretical scenarios such as an anti-ferromagnetic crystal, Coulomb induced micro-emulsions, and disorder driven puddle formation.