cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A numerical study of the quasinormal mode excitation of Kerr black holes
Creators: name: Dorband, Ernst Nils
name: Berti, Emanuele
name: Diener, Peter
name: Schnetter, Erik
name: Tiglio, Manuel
Publisher: name: arXiv
Year: 2006
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present numerical results from three-dimensional evolutions of scalar perturbations of Kerr black holes. Our simulations make use of a high-order accurate multi-block code which naturally allows for fixed adaptivity and smooth inner (excision) and outer boundaries. We focus on the quasinormal ringing phase, presenting a systematic method for extraction of the quasinormal mode frequencies and amplitudes and comparing our results against perturbation theory. The amplitude of each mode depends exponentially on the starting time of the quasinormal regime, which is not defined unambiguously. We show that this time-shift problem can be circumvented by looking at appropriately chosen relative mode amplitudes. From our simulations we extract the quasinormal frequencies and the relative and absolute amplitudes of corotating and counterrotating modes (including overtones in the corotating case). We study the dependence of these amplitudes on the shape of the initial perturbation, the angular dependence of the mode and the black hole spin, comparing against results from perturbation theory in the so-called asymptotic approximation. We also compare the quasinormal frequencies from our numerical simulations with predictions from perturbation theory, finding excellent agreement. Finally we study under what conditions the relative amplitude between given pairs of modes gets maximally excited and present a quantitative analysis of rotational mode-mode coupling. The main conclusions and techniques of our analysis are quite general and, as such, should be of interest in the study of ringdown gravitational waves produced by astrophysical gravitational wave sources.
description: 21 pages, 9 figures
La collera attraverso le citazioni poetiche nel quarto libro delle «Tusculanae disputationes» di Cicerone
Creators: name: Dal Chiele, Elisa
Publisher: name: Griseldaonline
Year: 2019
Subjects: Cicerone; ira; Lucilio; Accio; poesia; forza interiore; follia; psicopatologia

description: Il contributo prende in esame le citazioni poetiche che nel quarto libro delle Tusculanae disputationes Cicerone riferisce all’emozione della collera. Si studia in particolare la funzione delle citazioni poetiche e il loro effetto sulla prosa ciceroniana. Queste marcano alcuni snodi essenziali del ragionamento; talora servono a sminuire la tesi avversaria, talora sono auto-citazioni, mediante le quali Cicerone istituisce un rapporto intertestuale fra Tusculanae e De oratore. Da un lato, emerge la tendenza a minimizzare il dato fisico e la sintomatologia dell’ira, in modo coerente con il pensiero stoico qui seguito; dall’altro lato, affiora il peculiare interesse di Cicerone per l’espressione verbale della collera, strettamente collegata alla teoria e alla prassi oratoria.
description: Griseldaonline, Vol 18, No 2 (2019)
Reconstructing the primordial power spectrum - a new algorithm
Creators: name: Hannestad, Steen
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose an efficient and model independent method for reconstructing the primordial power spectrum from Cosmic Microwave Background (CMB) and large scale structure observations. The algorithm is based on a Monte Carlo principle and therefore very simple to incorporate into existing codes such as Markov Chain Monte Carlo. The algorithm has been used on present cosmological data to test for features in the primordial power spectrum. No significant evidence for features is found, although there is a slight preference for an overall bending of the spectrum, as well as a decrease in power at very large scales. We have also tested the algorithm on mock high precision CMB data, calculated from models with non-scale invariant primordial spectra. The algorithm efficiently extracts the underlying spectrum, as well as the other cosmological parameters in each case. Finally we have used the algorithm on a model where an artificial glitch in the CMB spectrum has been imposed, like the ones seen in the WMAP data. In this case it is found that, although the underlying cosmological parameters can be extracted, the recovered power spectrum can show significant spurious features, such as bending, even if the true spectrum is scale invariant.
description: 22 pages, 12 figures, matches JCAP published version
Defects During Conversion of Muscles to Meat
Creators: name: Phool Kanwar, Durga Bai Sodha, Pooja Gurjar, Saroj Katara
Publisher: name: The Science world a Monthly e magazine
Year: 2024

description:  

Introduction

·       Meat is a post rigor aspect of muscle and the conversion of muscle to meat is the result of series of biochemical, biophysical changes initiated in muscle at the death of the animal due to stoppage of the blood circulation (2).

·       The most immediate change caused due to bleeding is the cessation of the oxygen supply to the muscle resulting in inhibition of the cytochrome system & therefore, oxidative phosphorylation (1).
Accelerating Taub-NUT and Eguchi-Hanson solitons in four dimensions
Creators: name: Chng, Brenda
name: Mann, Robert
name: Stelea, Cristian
Publisher: name: arXiv
Year: 2006
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We construct new solutions of the vacuum Einstein field equations in four dimensions via a solution generating method utilizing the SL(2,R) symmetry of the reduced Lagrangian. We apply the method to an accelerating version of the Zipoy-Voorhees solution and generate new solutions which we interpret to be the accelerating versions of the Zipoy-Voorhees generalisation of the Taub-NUT solution (with Lorentzian signature) and the Zipoy-Voorhees generalisation of the Eguchi-Hanson solitons (with Euclidean signature). As an intermediary in the solution-generating process we obtain charged versions of the accelerated Zipoy-Voorhees-like families of solutions. Finally we present the accelerating version of the Taub-NUT solution and discuss its properties.
description: 16 pages
ANALYSIS OF ESCIN-CONTAINING RAW MATERIALS
Creators: name: Sharipov, A.T.
name: Hakimov, Sh.D.
name: Yokubova, N.J.
name: Sulaymonova, N.J.
name: Tursunov, X.O.
Publisher: name: Zenodo
Year: 2024

description: Following the Decree of the President of the Republic of Uzbekistan dated January 21, 2022, PD-55 "On additional measures for the accelerated development of the pharmaceutical industry of the Republic in 2022-2026", it has been established that industry experts should improve the provision of high-quality, effective, and safe pharmaceutical products to the population. This includes increasing production volume by three times through the introduction of advanced scientific and technical achievements and innovations to the pharmaceutical industry, and raising the level of provision of the domestic market to 80%.
La ‘graphic medicine’: curarsi con i comics
Creators: name: Calabrese, Stefano
Publisher: name: Griseldaonline
Year: 2019
Subjects: graphic novel; catarsi; patografie; malattie oncologiche; sindrome da stress post-traumatico

description: La narrative medicine si occupa delle relazioni medico-paziente e del miglioramento delle condizioni di salute dei malati attraverso forme molteplici di storytelling, dal cinema ai diari digitali. La graphic medicine si sta imponendo negli ultimi anni come forma di autocomprensione da parte di malati e disabili che, nel trasformare in immagini la loro sofferenza, riescono a esprimere meglio la loro condizione. Neuroscienziati e cognitivisti hanno infatti dimostrato come il coefficiente di empatia aumenta quando il linguaggio analogico si sostituisce a quello verbale, e la comunicazione avviene attraverso una progressiva fisicalizzazione delle emozioni. I graphic novel che raccontano il decorso delle malattie hanno una funzione terapeutica sia sugli autori che decidono di raccontarsi in prima o terza persona, sia sui lettori, in cui identificazioni empatiche e conseguenti processi catartici sono oggi rilevati sperimentalmente dalla comunità scientifica.
description: Griseldaonline, Vol 18, No 2 (2019)
Additional file 5 of Carriage of antimicrobial-resistant bacteria in a high-density informal settlement in Kenya is associated with environmental risk-factors
Creators: name: Omulo, Sylvia
name: Lofgren, Eric T.
name: Lockwood, Svetlana
name: Thumbi, Samuel M.
name: Bigogo, Godfrey
name: Ouma, Alice
name: Verani, Jennifer R.
name: Juma, Bonventure
name: Njenga, M. Kariuki
name: Kariuki, Samuel
name: McElwain, Terry F.
name: Palmer, Guy H.
name: Call, Douglas R.
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 5. Multivariable regression analysis for antimicrobial resistance load (Log10 CFU) at the adult level (≥18 years). Only variables with P < 0·2 in the univariable mixed-effects model were included in the multivariable model. Regression estimates (β) and 95% confidence intervals with P < 0·05 are shown in bold. P = 0·00 indicates P < 0·01.
Near infrared imaging of NGC2316
Creators: name: Teixeira, P. S
name: Fernandes, S. R.
name: Alves, J. F.
name: Correia, J. C.
name: Santos, F. D.
name: Lada, E. A.
name: Lada, C. J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In the present paper we present JHK photometric results of the young embedded cluster NGC 2316. We construct the cluster radial profile from which we determine a radius of 0.63 pc. We find 189 $\pm$ 29 cluster members in an extinction limited sub-sample of the survey, 22 $\pm$ 19 of which are possibly substellar. An average extinction of 4.5 visual magnitudes is derived using (H-K) colours of control fields. This extinction is due to the presence of residual parental molecular cloud. NGC 2316 presents 16% source fraction of excess emission which is consistent with other results from clusters with an age of 2-3 Myr. This age is consistent with the distribution of sources in the colour-magnitude diagram when compared to theoretical isochrones, and the overall shape of the cluster KLF. The substellar population of the cluster is similar or smaller than that observed for other embedded clusters and the stellar objects dominate the cluster membership.
description: 4 pages, 5 figures, accepted for publication in Astronomy & Astrophysics Letters. Full resolution images and paper available from http://www-cfa.harvard.edu/~pteixeir/NGC2316/
L’edizione 1958 dei «Racconti» di Italo Calvino: una soglia ermeneutica
Creators: name: Brigatti, Virna
Publisher: name: Griseldaonline
Year: 2019
Subjects: Italo Calvino; racconti; forma dell’edizione; indice; scritti editoriali

description: Il contributo prende in esame la prima edizione dei Racconti di Italo Calvino (Torino, Einaudi, coll. «Supercoralli», 1958) osservando la struttura del volume, sia dal punto di vista dell’indice, sia dal punto di vista della sua forma editoriale. Una volta affermata l’interdipendenza tra la forma di un’edizione e il costituirsi di un’opera letteraria, è possibile avviare un’indagine sui significati specifici che I racconti 1958 trasmettono, in particolare partendo da uno spunto interpretativo dato dallo scritto d’autore del risvolto di copertina. In quella sede, infatti, la raccolta di testi è definita un «Novellino dell’Italia contemporanea», elemento che permette di introdurre una rilettura dell’ultima sezione del volume, quella intitolata La vita difficile, in cui si collocano (in questo ordine) La formica argentina, La speculazione edilizia e La nuvola di smog. Tale rilettura considera in particolare la questione del ruolo dell’intellettuale di fronte alla storia e si inserisce nelle riflessioni intorno alla parabola della letteratura neorealista.
description: Griseldaonline, Vol 18, No 2 (2019)
Incremental to radical ideas: paradigm-relatedness metrics for investigating ideation creativity and diversity
Creators: name: Silk, Eli M.
name: Daly, Shanna R.
name: Jablokow, Kathryn W.
name: McKilligan, Seda
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Creativity and diversity are key components of success in idea generation, but each includes many dimensions. Paradigm-relatedness is an indicator of the style of creativity and diversity that has been overlooked often in assessing ideation. The goals for this study were to synthesize the literature on paradigm-relatedness, and develop and test alternative approaches for operationalizing paradigm-relatedness in ideation. The synthesis of the literature focused on reviewing both paradigm-relatedness theoretical frameworks and methodological approaches. Then, two alternative paradigm-relatedness metric approaches—category-based and component-based—were developed. Finally, ideation data was collected and coded to evaluate the reliability, ease of use, and potential applications of each approach. The category-based approach was a more reliable and faster way to code paradigm-relatedness, and so it may be more suited for research or evaluation at scale. In contrast, the component-based approach provided more explicit information on all aspects of paradigm-relatedness, but was more challenging to code reliably and more time-consuming. The component-based approach may be more suited to guiding smaller teams or individual designers in achieving paradigm-relatedness creativity and diversity. Neither approach was found to be universally ideal, and so consideration of the trade-offs is important in deciding which is most appropriate in a given situation.
IRFM T_eff calibrations for cluster and field giants in the Vilnius, Geneva, RI(C) and DDO photometric systems
Creators: name: Ramirez, I.
name: Melendez, J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Based on a large sample of disk and halo giant stars, for which accurate effective temperatures derived through the InfraRed Flux Method (IRFM) exist, a calibration of the temperature scale in the Vilnius, Geneva, RI(C) and DDO photometric systems is performed. We provide calibration formulae for the metallicity dependent T_eff vs color relations as well as grids of intrinsic colors and compare them with other calibrations. Photometry, atmospheric parameters and reddening corrections for the stars of the sample have been updated with respect to the original sources in order to reduce the dispersion of the fits. Application of our results to Arcturus leads to an effective temperature in excellent agreement with the value derived from its angular diameter and integrated flux. The effects of gravity on these T_eff vs color relations are also explored by taking into account our previous results for dwarf stars.
description: Accepted for publication in A&A
Divisibility of binomial coefficients by powers of two
Creators: name: Spiegelhofer, Lukas
name: Wallner, Michael
Publisher: name: arXiv
Year: 2017
Subjects: subject: Number Theory (math.NT)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 11B65, 05A16 (primary), 11A63, 11B50 (secondary)

description: For nonnegative integers $j$ and $n$ let $Θ(j,n)$ be the number of entries in the $n$-th row of Pascal's triangle that are not divisible by $2^{j+1}$. In this paper we prove that the family $j\mapstoΘ(j,n)$ usually follows a normal distribution. The method used for proving this theorem involves the computation of first and second moments of $Θ(j,n)$, and uses asymptotic analysis of multivariate generating functions by complex analytic methods, building on earlier work by Drmota (1994) and Drmota, Kauers and Spiegelhofer (2016).
description: 15 pages
Berry's phase for compact Lie groups
Creators: name: Strahov, E.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The Lie group adiabatic evolution determined by a Lie algebra parameter dependent Hamiltonian is considered. It is demonstrated that in the case when the parameter space of the Hamiltonian is a homogeneous Kähler manifold its fundamental Kähler potentials completely determine Berry geometrical phase factor. Explicit expressions for Berry vector potentials (Berry connections) and Berry curvatures are obtained using the complex parametrization of the Hamiltonian parameter space. A general approach is exemplified by the Lie algebra Hamiltonians corresponding to SU(2) and SU(3) evolution groups.
description: 24 pages, no figures
Additional file 2 of LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer
Creators: name: Cave, Donatella Delle
name: Buonaiuto, Silvia
name: Sainz, Bruno
name: Fantuz, Marco
name: Mangini, Maria
name: Carrer, Alessandro
name: Di Domenico, Annalisa
name: Iavazzo, Tea Teresa
name: Andolfi, Gennaro
name: Cortina, Carme
name: Sevillano, Marta
name: Heeschen, Christopher
name: Colonna, Vincenza
name: Corona, Marco
name: Cucciardi, Antonio
name: Di Guida, Martina
name: Batlle, Eduard
name: De Luca, Annachiara
name: Lonardo, Enza
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 2: Figure S2. Increased LAMC2 expression is associated with aggressive signature. (a) Dimensional reduction plot (DimPlot) of multiple cell types identified in PDAC primary tumors by single-cell RNA sequencing (scRNA-Seq). The clusters are color-coded based on cell types identified using known cell type-specific markers and are visualized using t-Distributed Stochastic Neighbor embedding (t-SNE). (b) Violin plot showing expression levels of LAMC2 in stromal versus ductal (tumor) cells identified in PDAC primary tumors by scRNA-Seq. (c) Violin plot showing the expression of LAMC2 in the 17 clusters identified in PDAC primary tumors by scRNA-Seq. (d) Percentage of LAMC2 positive cells in the different clusters identified in PDAC primary tumors by scRNA-Seq. (e) DotPlot depicting expression of ductal genes in the 17 clusters identified in PDAC primary tumors by scRNA-Seq. The size of the dots represents the percentage of cells expressing the gene within a cluster, whereas the colour intensity represents the average expression level. (f) DotPlot depicting expression of stem markers genes in the 17 clusters identified in PDAC primary tumors by scRNA-Seq. The size of the dots represents the proportion of cells expressing the gene whereas the colour intensity represents the average expression level. (g) Scatter plot of LAMC2 normalized expression in the Moffitt’s classical gene signature score of PDAC. (h) Scatter plot of LAMC2 normalized expression in the Moffitt’s basal-like gene signature score of PDAC.
SYK Model, Chaos and Conserved Charge
Creators: name: Bhattacharya, Ritabrata
name: Chakrabarti, Subhroneel
name: Jatkar, Dileep P.
name: Kundu, Arnab
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the SYK model with complex fermions, in the presence of an all-to-all $q$-body interaction, with a non-vanishing chemical potential. We find that, in the large $q$ limit, this model can be solved exactly and the corresponding Lyapunov exponent can be obtained semi-analytically. The resulting Lyapunov exponent is a sensitive function of the chemical potential $μ$. Even when the coupling $J$, which corresponds to the disorder averaged values of the all to all fermion interaction, is large, values of $μ$ which are exponentially small compared to $J$ lead to suppression of the Lyapunov exponent.
description: 18pages, 4 figures, v2:references and acknowledgment added, typos corrected
Bioactive mushroom polysaccharides as antitumor: an overview
Creators: name: Urja Pandya
name: Dhuldhaj, Umesh
name: Sahay, Nirmal S.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Plant Biology

description: Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person’s own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well as medicine. Mushrooms are well known for their bioactive compounds such as chizophyllan, lentinan, grifolan, PSP (polysaccharide-peptide complex) and PSK (polysaccharide-protein complex) which are considered as medicines against melignancy. They prevent oncogenesis by the direct effect on tumor metastasis and exhibits antitumor effects by the induction of immune response in host. Mushroom polysaccharides have promising future for treatment of cancers due to their mode of action and efficacy. Also there are some hurdles during this treatment, but it will start a new era of safer and effective medicine based on mushroom polysaccharides.
Critical frequencies of the ionospheric $F_1$ and $F_2$ layers during the last four solar cycles: sunspot group type dependencies
Creators: name: Yiğit, Erdal
name: Kilcik, Ali
name: Elias, Ana Georgina
name: Donmez, Burcin
name: Ozguc, Atila
name: Yurchshyne, Vasyl
name: Rozelot, Jean-Pierre
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: The long term solar activity dependencies of ionospheric F$_1$ and F$_2$ regions' critical frequencies ($f_0F_1$ and $f_0F_2$) are analyzed for the last four solar cycles (1976--2015). We show that the ionospheric F$_1$ and F$_2$ regions have different solar activity dependencies in terms of the sunspot group (SG) numbers: F$_1$ region critical frequency ($f_0F_1$) peaks at the same time with the small SG numbers, while the $f_0F_2$ reaches its maximum at the same time with the large SG numbers, especially during the solar cycle 23. The observed differences in the sensitivity of ionospheric critical frequencies to sunspot group (SG) numbers provide a new insight into the solar activity effects on the ionosphere and space weather. While the F$_1$ layer is influenced by the slow solar wind, which is largely associated with small SGs, the ionospheric F$_2$ layer is more sensitive to Coronal Mass Ejections (CMEs) and fast solar winds, which are mainly produced by large SGs and coronal holes. The SG numbers maximize during of peak of the solar cycle and the number of coronal holes peaks during the sunspot declining phase. During solar minimum there are relatively less large SGs, hence reduced CME and flare activity. These results provide a new perspective for assessing how the different regions of the ionosphere respond to space weather effects.
description: Accepted for publication in Journal of Atmospheric and Solar-Terrestrial Physics
title: Predicting flood insurance claims with hydrologic and socioeconomic demographics via machine learning: Exploring the roles of topography, minority populations, and political dissimilarity
Creators: name: Knighton, James
name: Buchanan, Brian
name: Guzman, Christian
name: Elliott, Rebecca
name: White, Eric
name: Rahm, Brian
Publisher: name: University of Massachusetts Amherst
Year: 2020
Subjects: subject: flooding insurance claims
subject: random forest
subject: vulnerability
subject: socio-hydrology
subject: flooding
subject: FEMA
subject: LIS-FLOOD

description: Current research on flooding risk often focuses on understanding hazards, de-emphasizing the complex pathways of exposure and vulnerability. We investigated the use of both hydrologic and social demographic data for flood exposure mapping with Random Forest (RF) regression and classification algorithms trained to predict both parcel- and tract-level flood insurance claims within New York State, US. Topographic characteristics best described flood claim frequency, but RF prediction skill was improved at both spatial scales when socioeconomic data was incorporated. Substantial improvements occurred at the tract-level when the percentage of minority residents, housing stock value and age, and the political dissimilarity index of voting precincts were used to predict insurance claims. Census tracts with higher numbers of claims and greater densities of low-lying tax parcels tended to have low proportions of minority residents, newer houses, and less political similarity to state level government. We compared this data-driven approach and a physically-based pluvial flood routing model for prediction of the spatial extents of flooding claims in two nearby catchments of differing land use. The floodplain we defined with physically based modeling agreed well with existing federal flood insurance rate maps, but underestimated the spatial extents of historical claim generating areas. In contrast, RF classification incorporating hydrologic and socioeconomic demographic data likely overestimated the flood-exposed areas. Our research indicates that quantitative incorporation of social data can improve flooding exposure estimates.
Metabolic plasticity in synthetic lethal mutants: viability at higher cost
Creators: name: Massucci, Francesco Alessandro
name: Sagués, Francesc
name: Serrano, M. Ángeles
Publisher: name: arXiv
Year: 2017
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: The most frequent form of pairwise synthetic lethality (SL) in metabolic networks is known as plasticity synthetic lethality (PSL). It occurs when the simultaneous inhibition of paired functional and silent metabolic reactions or genes is lethal, while the default of the functional reaction or gene in the pair is backed up by the activation of the silent one. Based on a complex systems approach and by using computational techniques on bacterial genome-scale metabolic reconstructions, we found that the failure of the functional PSL partner triggers a critical reorganization of fluxes to ensure viability in the mutant which not only affects the SL pair but a significant fraction of other interconnected reactions forming what we call a SL cluster. Interestingly, SL clusters show a strong entanglement both in terms of silent coessential reactions, which band together to form backup systems, and of other functional and silent reactions in the metabolic network. This strong overlap, also detected at the level of genes, mitigates the acquired vulnerabilities and increased structural and functional costs that pay for the robustness provided by essential plasticity. Finally, the participation of coessential reactions and genes in different SL clusters is very heterogeneous and those at the intersection of many SL clusters could serve as supertargets for more efficient drug action in the treatment of complex diseases and to elucidate improved strategies directed to reduce undesired resistance to chemicals in pathogens.
description: 10 pages, 4 figures, 15 supplementary figures
Passioni, fisiognomica, sopracciglia
Creators: name: Rodler, Lucia
Publisher: name: Griseldaonline
Year: 2019
Subjects: zoomorfismo; trasparenza psicofisica; folk psychology; iperbole; similitudine

description: L’articolo riflette sul rapporto tra pregiudizi, fisiognomica e passioni, concentrandosi sulla fisionomia delle sopracciglia. Tra Cinque e Seicento, questa piccola parte del corpo viene descritta in modo diverso da Giambattista della Porta, fisionomo napoletano conosciuto a livello europeo per il Della fisonomia dell’uomo (1586); da Cornelio Ghirardelli, scrittore bolognese che promuove la convergenza tra fisiognomica e letteratura nella Cefalogia fisionomica (1630); e da Charles le Brun, artista francese e studioso delle passioni nella Conférence sur l’expression générale et particulière (1698). Le indagini di questi trattatisti sono un esercizio di mind reading, esercitano cioè la capacità di leggere le intenzioni di chi ci sta di fronte, osservando l’aspetto esteriore. Per fare ciò, essi utilizzano la similitudine, spesso iperbolica, con gli animali (mostrando una abile capacità di blending) e si riferiscono anche a personaggi storici o letterari presenti nell’immaginario condiviso. In questo modo rendono possibile l’empatia e così, forse, anche una vita migliore.
description: Griseldaonline, Vol 18, No 2 (2019)
Additional file 3 of LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer
Creators: name: Cave, Donatella Delle
name: Buonaiuto, Silvia
name: Sainz, Bruno
name: Fantuz, Marco
name: Mangini, Maria
name: Carrer, Alessandro
name: Di Domenico, Annalisa
name: Iavazzo, Tea Teresa
name: Andolfi, Gennaro
name: Cortina, Carme
name: Sevillano, Marta
name: Heeschen, Christopher
name: Colonna, Vincenza
name: Corona, Marco
name: Cucciardi, Antonio
name: Di Guida, Martina
name: Batlle, Eduard
name: De Luca, Annachiara
name: Lonardo, Enza
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 3: Figure S3. LAMC2 expression correlates with CSC content and function. (a) qPCR analysis of LAMC2 gene expression in adherent cells versus spheres. Data are normalized to GAPDH and are presented as fold change in gene expression relative to adherent cells (indicated as Adh). (b) Western blot analysis of LAMC2 in adherent cells versus spheres. Parallel β-ACTIN immunoblotting was performed. (c) qPCR analysis for CD44, CD133 and L1CAM genes in adherent cells versus spheres. Data are normalized to GAPDH and are presented as fold change in gene expression relative to adherent cells. (d) Correlation between CD44 and LAMC2 in PDAC samples from the TCGA dataset. The p value is based on Pearson’s Correlation. (e) qPCR analysis for LAMC2 in PDAC cells grown in different culture conditions. (f) qPCR analysis for LAMC2, ABCG2, CD133, L1CAM and SOX2 in Adh vs Spheres vs Differentiated cells. Data are normalized to GAPDH and are presented as fold change in gene expression relative to adherent cells. (g) Representative images of L3.6pl and PANC-1 cells growth after short (24 hours) or long (7 days) times in Diff. medium compared to CSC medium. (h) qPCR analysis for CD44 and LAMC2 genes in CD44+ sorted cells. Data are normalized to GAPDH and are presented as fold change in gene expression relative to CD44-cells. (i) qPCR analysis for CD133 and LAMC2 genes in CD133+ sorted cells. Data are normalized to GAPDH and are presented as fold change in gene expression relative to CD133- cells. (j) qPCR analysis for LAMC2 in PDAC cells treated with 100 µM of gemcitabine. Data are normalized to GAPDH and are presented as fold change in gene expression relative to control cells (untreated). *p<0.05, **p<0.005, ***p<0.0005. n $$\ge 3.$$ ≥ 3 . Statistical significance was assessed by Student's t-test.
title: Lys :
title: Principes directeurs pour la conduite de l’examen de la distinction, de l’homogénéité et de la stabilité.
titleType: Subtitle
Creators: name: (:Unas)
Publisher: name: Unknown
Year: 2011

description: Ces principes directeurs (“principes directeurs d’examen”) visent à approfondir les principes énoncés dans l’introduction générale (document TG/1/3) et dans les documents TGP qui s’y rapportent afin de donner des indications concrètes détaillées pour l’harmonisation de l’examen de la distinction, de l’homogénéité et de la stabilité (DHS) et, en particulier, à identifier des caractères convenant à l’examen DHS et à la production de descriptions variétales harmonisées.
A geometrical approach to non-adiabatic transitions in quantum theory: applications to NMR, over-barrier reflection and parametric excitation of quantum oscillator
Creators: name: Marinov, M. S.
name: Strahov, E.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: This article deals with non-adiabatic processes (i.e. processes excluded by the adiabatic theorem) from the geometrical (group-theoretical) point of view. An approximated formula for the probabilities of the non-adiabatic transitions is derived in the adiabatic regime for the case when the parameter-dependent Hamiltonian represents a smooth curve in the Lie algebra and the quantal dynamics is determined by the corresponding Lie group evolution operator. We treat the spin precession in a time-dependent magnetic field and the over-barrier reflection problem in a uniform way using the first-order dynamical equations on SU(2) and $SU(1.1)$ group manifolds correspondingly. A comparison with analytic solutions for simple solvable models is provided.
description: 15 pages, 2 figures
Swapping of Gaussian Einstein-Podolsky-Rosen steering
Creators: name: Wang, Meihong
name: Qin, Zhongzhong
name: Su, Xiaolong
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Einstein-Podolsky-Rosen (EPR) steering is a quantum mechanical phenomenon that allows one party to steer the state of a distant party by exploiting their shared entanglement. It has potential applications in secure quantum communication. In this paper, we present two swapping schemes of Gaussian EPR steering, single-channel and dual-channel schemes, by the technique of entanglement swapping. Two space-separated independent EPR steering states without a direct interaction present EPR steering after deterministic swapping. By comparing the EPR steering of the single-channel and dual-channel schemes, we show that the transmission distance of the single-channel scheme is much longer than that of the symmetric dual-channel scheme. Different from entanglement swapping, one-way EPR steering is presented after swapping over lossy channels. The most interesting thing is that the change of the EPR steering direction is observed in the dual-channel scheme. We also show that excess noise in a quantum channel will shorten the transmission distance of the swapping, even leading to the sudden death of EPR steering. The presented schemes provide a technical reference for remote quantum communications with EPR steering.
Demonstration of displacement- and frequency-noise free laser interferometry using bi-directional Mach-Zehnder interferometers
Creators: name: Sato, Shuichi
name: Kawamura, Seiji
name: Kokeyama, Keiko
name: Ward, Robert L.
name: Chen, Yanbei
name: Pai, Archana
name: Somiya, Kentaro
Publisher: name: arXiv
Year: 2006
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have demonstrated displacement- and frequency-noise free laser interferometry (DFI) by partially implementing a recently proposed optical configuration using bi-directional Mach-Zehnder interferometers (MZI). This partial implementation, the minimum necessary to be called DFI, has confirmed the essential feature of DFI: the combination of two MZI signals can be carried out in a way which cancels displacement noise of the mirrors while maintaining gravitational wave signals. The attained maximum displacement noise suppression allowed a simulated-SNR of 45dB.
description: 5 pages, 5 figures, now on PRL 98, 141101 (2007)
First Principles Study of the Giant Magnetic Anisotropy Energy in Bulk Na4IrO4
Creators: name: Wang, Di
name: Tang, Feng
name: Du, Yongping
name: Wan, Xiangang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: In 5d transition metal oxides, novel properties arise from the interplay of electron correlations and spin--orbit interactions. Na4IrO4, where 5d transition-metal Ir atom occupies the center of the square-planar coordination environment, is synthesized. Based on density functional theory, we calculate its electronic and magnetic properties. Our numerical results show that the Ir-5d bands are quite narrow, and the bands around the Fermi level are mainly contributed by d_{xy},d_{yz} and d_{zx} orbitals. The magnetic easy-axis is perpendicular to the IrO4 plane, and the magnetic anisotropy energy (MAE) of Na4IrO4 is found to be very giant. We estimate the magnetic parameters by mapping the calculated total energy for different spin configurations onto a spin model. The next nearest neighbor exchange interaction J2 is much larger than other intersite exchange interactions and results in the magnetic ground state configuration. Our study clearly demonstrates that the huge MAE comes from the single-ion anisotropy rather than the anisotropic interatomic spin exchange. This compound has a large spin gap but very narrow spin-wave dispersion, due to the large single-ion anisotropy and relatively small exchange couplings. Noticing this remarkable magnetic feature originated from its highly isolated IrO4 moiety, we also explore the possiblity to further enhance the MAE.
Cosmic acceleration vs axion-photon mixing
Creators: name: Bassett, Bruce A.
name: Kunz, Martin
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Axion-photon mixing has been proposed as an alternative to acceleration as the explanation for supernovae dimming. We point out that the loss of photons due to this mixing will induce a strong asymmetry between the luminosity, d_L(z), and angular-diameter distance, d_A(z), since the latter is unaffected by mixing. In a first search for such an asymmetry we introduce a dimensionless mixing amplitude lambda so that lambda=0 if no photons are lost and lambda = 1 if axion-photon mixing occurs. The best-fit to SNIa and radio galaxy data is lambda = -0.3^{+0.6}_{-0.4} (95% CL), corresponding to an unphysical, negative, mixing length. This same argument limits the attenuation of light from supernovae due to dust. We show that future d_L and d_A data from SNAP and galaxy surveys such as DEEP2 and KAOS will detect or rule out mixing at more than 5-sigma, almost independently of the dark energy dynamics. Finally we discuss the constraints from the near maximal polarisation of the gamma-ray burst (GRB) GRB021206. Since mixing reduces the polarisation of distant sources, future observations of high redshift GRBs may provide orthogonal constraints on axion-photon mixing and related scenarios.
description: 4 pages, 4 colour figures. Matches version to appear in ApJ. Significantly stronger constraints arising from new data: universe still accelerating at 3 sigma
Cumulative impacts of climate change and oil pollution on Arctic copepods
Creators: name: Rist, Sinja
name: Rask, Sofie
name: Ntinou, Iliana V.
name: Varpe, Øystein
name: Lindegren, Martin
name: Ugwu, Kevin
name: Larsson, Maria
name: Sjöberg, Viktor
name: Nielsen, Torkel Gissel
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Arctic
subject: Climate change
subject: Pollution

description: This presentation was held in March 2024 during the 7th International Zooplankton Production Symposium in Hobart (Australia)

Abstract:

Arctic biota are exposed to multiple stressors, among these climate change and pollution. These are expected to increase in the Arctic in the future. Still, their combined impact on the marine ecosystem is not well understood. In this study, we investigated the cumulative impact of crude oil, warming and freshening on the feeding of the copepod species Calanus glacialis and Calanus finmarchicus in Western Greenland. Adult females were exposed to ambient conditions (0°C + 33 psu) and two scenarios of climate change: 5°C + 27 psu (Scenario 1), 5°C + 20 psu (Scenario 2). All three conditions were tested in the absence and presence of mechanically dispersed crude oil (1 µL L-1). During the six days of exposure, incubations were renewed daily and the number of fecal pellets was counted. The fecal pellet volume was measured three times. Warming from 0 to 5°C plus freshening from 33 to 27 psu resulted in a significant increase in feeding for both species. However, when salinity dropped to 20 psu (at 5°C) feeding decreased for C. glacialis, while it fluctuated for C. finmarchicus. For both species, oil had the strongest effect, leading to a 68-83% reduction in feeding. This overshadowed any differences between climatic conditions. All three stressors had significant single effects and several joint effects on feeding. The results demonstrate the sensitivity of Arctic copepods to environmentally realistic concentrations of crude oil and climate change.
Type I shell galaxies as a test of gravity models
Creators: name: Vakili, Hajar
name: Kroupa, Pavel
name: Rahvar, Sohrab
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Shell galaxies are understood to form through the collision of a dwarf galaxy with an elliptical galaxy. Shell structures and kinematics have been noted to be independent tools to measure the gravitational potential of the shell galaxies. We compare theoretically the formation of shells in Type I shell galaxies in different gravity theories in this work because this is so far missing in the literature. We include Newtonian plus dark halo gravity, and two non-Newtonian gravity models, MOG and MOND, in identical initial systems. We investigate the effect of dynamical friction, which by slowing down the dwarf galaxy in the dark halo models limits the range of shell radii to low values. Under the same initial conditions, shells appear on a shorter timescale and over a smaller range of distances in the presence of dark matter than in the corresponding non-Newtonian gravity models. If galaxies are embedded in a dark matter halo, then the merging time may be too rapid to allow multi-generation shell formation as required by observed systems because of the large dynamical friction effect. Starting from the same initial state, in the dark halo model the observation of small bright shells should be accompanied by large faint ones, while for the case of MOG, the next shell generation patterns iterate with a specific time delay. The first shell generation pattern shows a degeneracy with the age of the shells and in different theories, but the relative distance of the shells and the shell expansion velocity can break this degeneracy.
description: 14 pages, 10 figures, accepted for publication in ApJ, final version, some references edited
Sequencing of Vibrio cholerae mutants.pdf
Creators: name: Mitesh Dongre
name: Bhupender Singh
name: Kyaw Min Aung
name: Larsson, Per
name: Miftakhova, Regina
name: Persson, Karina
name: Askarian, Fatemeh
name: Johannessen, Mona
name: Hofsten, Jonas Von
name: Persson, Jenny L.
name: Erhardt, Marc
name: Tuck, Simon
name: Uhlin, Bernt Eric
name: Wai, Sun Nyunt
Publisher: name: figshare
Year: 2018
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology

description: PCR amplification was performed using Phusion DNA polymerae (Thermo Scientific) according to manufacture's recommendation. In-frame deletion in V. cholerae was performed as descibed. Briefly, a 500-bp 5-prime flanking sequence of the gene, including several nucleotides of the coding region, was PCR amplified. The two PCR products were annealed at their overlapping region and amplified by PCR to produce a single DNA fragment, using outer primers. The resulting PCR product, lacking most of the coding sequence of the gene, was digested with XbaI enzyme and ligated into a similarly digested pCVD442 suicide plasmid. pCVD442 containing mutant construct was introduced into E. coli SM10.lambda pir by electroporation. The donor, E. coli SM10-lambda pir containing the plasmid pCVD442 containing mutant construct, was used for conjugal transfer to rifampin-resistant V. cholerae A1552. A mixture containing equal volumes of the donor and recipient in LB was incubated for 6 h at 30C. The exconjugants were selected by plating the suspension onto LB plates supplemented with 100 microgram/ml of rifampin and 100 microgram/ml of carbenicillin (Cb) at 30C. After selection of the desired tranconjugants on rifampin-plus-Cb plates, they were streaked on LB plates with 10 percent sucrose at 30C. Several colonies were purified from the plates, tested for Cb sensitivity, and then analyzed for the deletion using colony PCR and DNA sequencing. Sequencing data are described here.
INDEPENDENT EDUCATION OF STUDENTS AS A FACTOR FOR IMPROVING THE QUALITY OF PROFESSIONAL TRAINING
Creators: name: Azamkhanov Saidabzalkhan "Sociology" department Foundation Doctoral Student (PhD)
Publisher: name: Zenodo
Year: 2024

description: This in the article of students independent education get professional preparation quality increase, in education professional skills in raising high to the results reach person in formation independent education important factor about word is held

KEY WORDS: independent research, teaching goals, technological process ,scientific research , doctor of science
Stochastic Reduction in Nonlinear Quantum Mechanics
Creators: name: Brody, D. C.
name: Hughston, L. P.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Stochastic extensions of the Schrodinger equation have attracted attention recently as plausible models for state reduction in quantum mechanics. Here we formulate a general approach to stochastic Schrodinger dynamics in the case of a nonlinear state space of the type proposed by Kibble. We derive a number of new identities for observables in the nonlinear theory, and establish general criteria on the curvature of the state space sufficient to ensure collapse of the wave function.
description: 4 pages