cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effect of Bacterial Community and Free Amino Acids on the Content of Biogenic Amines During Fermentation of Yu-lu, a Chinese Fermented Fish Sauce
Creators: name: Wang, Yueqi
name: Li, Chunsheng
name: Li, Laihao
name: Yang, Xianqing
name: Wu, Yanyan
name: Zhao, Yongqiang
name: Wei, Ya
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: The main objective of this work was to investigate the effects of bacterial community and free amino acids on the content of biogenic amines in Yu-lu during fermentation. Four major biogenic amines (histamine, tyramine, cadaverine, and putrescine) were identified, and the content of tyramine was positively correlated with histamine (R value = 0.9113). Aspartic acid, glutamic acid, histidine, leucine, and lysine were the dominant free amino acids. 16S rRNA sequencing showed that the composition of the bacterial community changed significantly during fermentation of Yu-lu. Principal component analysis revealed the crucial links between microbial community and biogenic amines. For example, Halanaerobium was probably associated with the formation of putrescine, while Halomonas might be associated with the degradation of biogenic amines at the end of fermentation of Yu-lu. This study provided a detailed evaluation of the Yu-lu fermentation process, enabling development of better strategies for biogenic amine control in fish sauce.
Real-Time 3D Audio Spatialization Tools for Interactive Performance
Creators: name: Pérez-López, Andrés
Publisher: name: Zenodo
Year: 2014
Subjects: Spatial Audio
SuperCollider
Human-Computer Interaction

description: Spatial position is one of the main perceivable sound characteristics. Due to historical and technological reasons, however, it has been not fully exploited until last decades. Current technologies for compositional, offline spatialization are already consolidated; but the online domain remains still in a development stage, due to the inherent complexity added by the realtime control paradigm. We propose a theoretical basis for the analysis and design of realtime spatialization systems, borrowing the knowledge and tools from the Human Computer Interaction and Digital Musical Instrument design fields, and thus developing the concept of spatialization instruments. Based on that, we perform an analysis of both existing realtime sound spatialization software and recently developed interfaces for realtime sound spatialization control. Furthermore, on top of the design criteria provided by the analysis, we developed the SCLiss: SuperCollider Live Spatialization System, a new tool for helping in the spatialization instruments design process, and proposed an interface prototype as an example of the tool’s possibilities.
Additional file 1: of Variable-angle epifluorescence microscopy characterizes protein dynamics in the vicinity of plasma membrane in plant cells
Creators: name: Chen, Tong
name: Ji, Dongchao
name: Tian, Shiping
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Methodology for determining incident angle and penetration depth. (PDF 569 Â kb)
title: 02_1651
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: LaMOP

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Additional file 2: of Variable-angle epifluorescence microscopy characterizes protein dynamics in the vicinity of plasma membrane in plant cells
Creators: name: Chen, Tong
name: Ji, Dongchao
name: Tian, Shiping
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Figure S1. Organellar dynamics are resolved in high spatio-temporal manner under VAEM. Figure S2. VAEM is applicable to epidermal cells of different tissues from seedlings. Figure S3. CLC-GFP tagged punctate structures correspond to clathrin-coated vesicles and Golgi apparatuses, depending on the angle of incident light. Figure S4. Actin turnover resolved using VAEM. Figure S5. Microtubular organization as revealed by VAEM. Figure S6. SKU5-GFP localizes to plasma membrane and intracellular structures. Figure S7. Distribution of the fluorescence intensity of the diffraction-limited single pCLC2- myristoyl-mGFPA206K spots. Figure S8. Fluorescence correlation spectroscopy (FCS) to examine the fluorescence fluctuation in response to TyrA23 treatment. Figure S9. Analysis on MSD for different trajectories and categorization into various diffusion regimes. Figure S10. Representative kymographs for BOR1 and Lti6a. (PDF 1148Â kb)
title: On properties and structure of the analytic singular value decomposition
Creators: name: Weiss, Stephan
name: Proudler, Ian K.
name: Barbarino, Giovanni
name: Pestana, Jennifer
name: McWhirter, John G.
Publisher: name: Strathprints - University of Strathclyde
Year: 2024

description: We investigate the singular value decomposition (SVD) of a rectangular matrix A(z) of functions that are analytic on an annulus that includes at least the unit circle. Such matrices occur, e.g., as matrices of transfer functions representing broadband multiple-input multiple-output systems. Our analysis is based on findings for the analytic SVD applicable to continuous time systems, and on the analytic eigenvalue decomposition. Using these, we establish two potentially overlapping cases where analyticity of the SVD factors is denied. Firstly, from a structural point of view, multiplexed systems require oversampling by the multiplexing factor in order to admit an analytic solution. Secondly, from an algebraic perspective, we state under which condition spectral zeroes of any singular value require additional oversampling by a factor of two if an analytic solution is to be found. In all other cases, an analytic matrix admits an analytic SVD, whereby the singular values are unique up to a permutation, and the left- and right-singular vectors are coupled through a joint ambiguity w.r.t.~an arbitrary allpass function. We demonstrate how some state-of-the-art polynomial matrix decomposition algorithms approximate this solution, motivating the need for dedicated algorithms.
Investigating the role of autophagy in herpes simplex encephalitis
Creators: name: Haji Ahmad, Nur Liyana
Publisher: name: Imperial College London
Year: 2018

description: The role of autophagy in innate immunity has recently garnered attention from molecular biologists and pathologists alike. A growing number of reports suggest its anti-viral role in various infections, including Herpes simplex virus 1 (HSV1) which is the causative pathogen for herpes simplex encephalitis (HSE). Whilst studies have shown the non-redundant role of Toll-like receptor 3 (TLR3)-interferon (IFN) signalling pathway in HSV1 defence, the role of autophagy in HSV1 infection and HSE pathogenesis remains elusive. In this study, we characterised autophagy phenotypes in response to rapamycin, poly(I:C), c-di-GMP and HSV1 dsDNA stimulations as well as HSV1 infection, of human dermal fibroblasts derived from HSE patients harbouring mutations in components of the TLR3-IFN pathway – UNC93B1 (c.103del4), TLR3 (p.R867Q), TRIF (p.R141X), TRAF3 (p.R118W) and TBK1 (p.D50A and p.G159A). By using the autophagy marker LC3B, we established the HSV1-induced formation of two distinct autophagy phenotypes: cytoplasmic and perinuclear LC3B phenotypes. We correlated the former with the host protective autophagy response triggered early in HSV1 infection, which is TBK1-dependent but TLR3- and IFN-independent, and can be induced in neighbouring non-infected cells. Fibroblasts carrying the G159A mutation in TBK1 failed to induce LC3BII:I and reduce the autophagy adaptor p62 protein levels, suggesting a defect in autophagy response upon HSV1 infection. This impairment is reproducible by inhibiting TBK1 function using TBK1 inhibitor BX795 and depleting endogenous TBK1 in control fibroblasts. Furthermore, we demonstrated the cytoprotective nature of autophagy in HSV1 infection, whereby prior upregulation of autophagy by rapamycin in fibroblasts, led to enhanced cell viability following HSV1 infection.
‘Murundus’ structures in the semi-arid region of Brazil: testing their geographical congruence with mound-building termites (Blattodea: Termitoidea: Termitidae)
Creators: name: Souza, Henrique Jesus De
name: Delabie, Jacques Hubert Charles
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Summary. Earth mounds called ‘murundus’ are conspicuous features in the semi-arid region of Brazil, where their distribution and origin remain largely unknown. We adopted an approach based on spatially explicit mapping and modeling to determine the current and potential geographical distribution of murundus. We set up a systematic grid survey to map their current distribution using high-resolution satellite imagery available via free open source software. To obtain insights into the origin of these earth mounds, predictive models were used to test their geographical congruence with six mound-building termites (genera Cornitermes Wasmann, 1897, and Syntermes Holmgren, 1909). The Maxent algorithm was used to generate the potential distribution models based on a set of five variables related to primary environmental regimes that determine the fundamental niche of termite species. To analyze if there was some congruence between associated environmental variables, we cross-checked the results obtained from the statistical tests using MAXENT software. Murundus mostly occur in the south-central region of the Caatinga biome (i.e. seasonally dry tropical forest) in areas with moderate annual mean temperature (20–24°C) and precipitation (600–910 mm), and soils with moderate to severe constraints concerning nutrient availability. We observed a strong geographical congruence between the potential distributions of densely packed murundus and four mound-building termites [i.e. Cornitermes bequaerti Emerson, 1952, C. silvestrii Emerson, 1949, Syntermes dirus (Burmeister, 1839) and S. wheeleri (Emerson, 1925)]. Based on the significant association of those distributions with the climate and soil nutrient availability, we concluded that the formation of murundus in the semi-arid domain might be an adaptive response of mound-building termites to particular regional environmental conditions.
Dilated cardiomyopathy: remodelling, risk stratification and personalising therapy
Creators: name: Halliday, Brian P.
Publisher: name: Imperial College London
Year: 2018

description: Introduction: Dilated cardiomyopathy (DCM) is a common heterogeneous disease with variable outcomes. Unmet needs include the improvement of risk stratification, particularly in patients with mild and moderately reduced left ventricular ejection fraction (LVEF). It is also unclear whether DCM patients with improved LVEF simply have remission of disease or have permanently recovered. The benefit of continued therapy is unclear. Methods & Results: We investigated the use of late gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR) in the risk stratification of patients with DCM in a large registry. The presence of mid-wall LGE was associated with a nine-fold increase in the risk of SCD events in patients with mild and moderately reduced LVEF. In a study, including patients of all disease severities, the presence of septal LGE was most strongly associated with all-cause mortality whilst septal and left ventricular free-wall enhancement was associated with the greatest risk of SCD events. For both end-points, even small degrees of LGE were associated with large increases in risk. We also demonstrated that women with DCM have markers of less severe disease and reduced adjusted all-cause mortality compared to men with the disease. In addition, the safety and feasibility of heart failure therapy withdrawal in DCM patients with improved LVEF, normal left ventricular cavity size and low natriuretic peptide concentration was investigated in a randomised controlled trial. The preliminary results of the first 35 patients enrolled demonstrated that 41.2% of patients suffered a relapse within 6 months of starting therapy withdrawal compared to none of the patients in the control arm. Conclusions: LGE-CMR can identify patients at risk of SCD. Women with DCM have better outcomes compared to men. At least a proportion of patients with improved LVEF continue to benefit from therapy. Routine withdrawal of therapy in this group is unwise.
Additional file 1: of Cost-effectiveness of healthy eating and/or physical activity promotion in pregnant women at increased risk of gestational diabetes mellitus: economic evaluation alongside the DALI study, a European multicenter randomized controlled trial
Creators: name: Broekhuizen, Karen
name: Simmons, David
name: Devlieger, Roland
name: van Assche, AndrĂŠ
name: Jans, Goele
name: Galjaard, Sander
name: Corcoy, Rosa
name: Adelantado, Juan
name: Dunne, Fidelma
name: Desoye, Gernot
name: Harreiter, JĂźrgen
name: Kautzky-Willer, Alexandra
name: Damm, Peter
name: Mathiesen, Elisabeth
name: Jensen, Dorte
name: Andersen, Liselotte
name: Lapolla, Annunziata
name: Dalfra, Maria
name: Bertolotto, Alessandra
name: Wender-Ozegowska, Ewa
name: Zawiejska, Agnieszka
name: Hill, David
name: Snoek, Frank
name: Jelsma, Judith
name: Bosmans, Judith
name: van Poppel, Mireille
name: van Dongen, Johanna
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: CONSORT 2010 checklist of information to include when reporting a randomized trial. (DOC 217 kb)
Supplementary Materials from Threshold effect of growth rate on population variability of Escherichia coli cell lengths
Creators: name: Manasi S. Gangan
name: Chaitanya A. Athale
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology

description: A long-standing question in biology is the effect of growth on cell size. Here, we estimate the effect of Escherichia coli growth rate (r) on population cell size distributions by estimating the coefficient of variation of cell lengths (CVL) from image analysis of fixed cells in DIC microscopy. We find that the CVL is constant at growth rates less than one division per hour, whereas above this threshold, CVL increases with an increase in the growth rate. We hypothesize that stochastic inhibition of cell division owing to replication stalling by a RecA-dependent mechanism, combined with the growth rate threshold of multi-fork replication (according to Cooper and Helmstetter), could form the basis of such a threshold effect. We proceed to test our hypothesis by increasing the frequency of stochastic stalling of replication forks with hydroxyurea (HU) treatment and find that cell length variability increases only when the growth rate exceeds this threshold. The population effect is also reproduced in single-cell studies using agar-pad cultures and ‘mother machine’-based experiments to achieve synchrony. To test the role of RecA, critical for the repair of stalled replication forks, we examine the CVL of E. coli ΔrecA cells. We find cell length variability in the mutant to be greater than wild-type, a phenotype that is rescued by plasmid-based RecA expression. Additionally, we find that RecA-GFP protein recruitment to nucleoids is more frequent at growth rates exceeding the growth rate threshold and is further enhanced on HU treatment. Thus, we find growth rates greater than a threshold result in increased E. coli cell lengths in the population, and this effect is, at least in part, mediated by RecA recruitment to the nucleoid and stochastic inhibition of division.
Additional file 2: of Cost-effectiveness of healthy eating and/or physical activity promotion in pregnant women at increased risk of gestational diabetes mellitus: economic evaluation alongside the DALI study, a European multicenter randomized controlled trial
Creators: name: Broekhuizen, Karen
name: Simmons, David
name: Devlieger, Roland
name: van Assche, AndrĂŠ
name: Jans, Goele
name: Galjaard, Sander
name: Corcoy, Rosa
name: Adelantado, Juan
name: Dunne, Fidelma
name: Desoye, Gernot
name: Harreiter, JĂźrgen
name: Kautzky-Willer, Alexandra
name: Damm, Peter
name: Mathiesen, Elisabeth
name: Jensen, Dorte
name: Andersen, Liselotte
name: Lapolla, Annunziata
name: Dalfra, Maria
name: Bertolotto, Alessandra
name: Wender-Ozegowska, Ewa
name: Zawiejska, Agnieszka
name: Hill, David
name: Snoek, Frank
name: Jelsma, Judith
name: Bosmans, Judith
name: van Poppel, Mireille
name: van Dongen, Johanna
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: TIDieR (Template for Intervention Description and Replication) Checklist. (DOCX 39 kb)
Defining the impact of Ibrutinib therapy and CFTR dysfunction on macrophage function in the innate immune response to Aspergillus fumigatus
Creators: name: Bercusson, Amelia
Publisher: name: Imperial College London
Year: 2019

description: Over recent years, the role of fungal pathogens within the respiratory microbiome has been increasingly recognised. Aspergillus fumigatus is the most commonly isolated organism and gives rise to a wide spectrum of disease, the nature of which depends on the outcome of the host-pathogen interaction. While the majority of people who inhale Aspergillus spores on a daily basis clear them without consequence, certain subgroups of the population appear to be pre-disposed to develop clinical disease. Patients with specific forms of immunocompromise are known to be susceptible to invasive infection but in others who develop Aspergillus lung disease, the nature of the immune dysfunction present is not clear. This PhD aimed to clarify the mechanisms of immune dysfunction that underlay two different clinical groups’ predisposition to Aspergillus lung disease, namely patients treated with Ibrutinib and patients with Cystic Fibrosis. I established that Ibrutinib inhibits the activation of signalling pathways crucial to normal macrophage function, thus compromising the innate immune response to Aspergillus fumigatus. Ibrutinib was also shown to suppress macrophage programmed necrotic cell death. Following on from this finding, I was able to demonstrate that necroptosis is a significant mode of programmed cell death in Aspergillus-infected macrophages and is regulated by signalling along a TLR9-BTK mediated pathway. The clinical phenotype of fungal disease in Cystic Fibrosis is different, being characterised by chronic infection and allergy. In an in-vitro model, I showed that dysfunctional signalling within CFTR-deficient macrophages gives rise to a hyper-inflammatory response to Aspergillus fumigatus characterised by increased cytokine release, excess macrophage cell death and impaired fungal killing. In an in-vivo model, this exaggerated inflammatory response was ineffective in clearing Aspergillus from the airways and gave rise to a phenotype of chronic neutrophilic inflammation consistent with CF clinical disease.
Cyanobacteria-Fungi: Friends to Waste Water Treatment.
Creators: name: Kanjilal, Shubhangi
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 410504
subject: Surface water quality processes and contaminated sediment assessment
classificationCode: 410599
subject: Pollution and contamination not elsewhere classified
classificationCode: 410501
subject: Environmental biogeochemistry

description: The cyanobacterium species Scytonema was extracted from a polluted lake while the fungal species Aspergillus flavus was isolated from rotten apples and pears. These have originated in different environments and were exposed to different media. They were co-cultured for 45 days, as well as cultured separately in BG11 medium, cyanobacteria spent medium, fungal spent medium and domestic primary effluent collected from a local open drainage. The observation portrayed their mutualistic relationship to one another and their efficiency in treating wastewater. Such a relationship has led to a decrease in the percentage of biomass and thus in-turn, helping us analyze its effect in treating wastewater systems.
Additional file 3: of Cost-effectiveness of healthy eating and/or physical activity promotion in pregnant women at increased risk of gestational diabetes mellitus: economic evaluation alongside the DALI study, a European multicenter randomized controlled trial
Creators: name: Broekhuizen, Karen
name: Simmons, David
name: Devlieger, Roland
name: van Assche, AndrĂŠ
name: Jans, Goele
name: Galjaard, Sander
name: Corcoy, Rosa
name: Adelantado, Juan
name: Dunne, Fidelma
name: Desoye, Gernot
name: Harreiter, JĂźrgen
name: Kautzky-Willer, Alexandra
name: Damm, Peter
name: Mathiesen, Elisabeth
name: Jensen, Dorte
name: Andersen, Liselotte
name: Lapolla, Annunziata
name: Dalfra, Maria
name: Bertolotto, Alessandra
name: Wender-Ozegowska, Ewa
name: Zawiejska, Agnieszka
name: Hill, David
name: Snoek, Frank
name: Jelsma, Judith
name: Bosmans, Judith
name: van Poppel, Mireille
name: van Dongen, Johanna
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Unit costs used for valuing resource use in the main analysis. (DOCX 493 kb)
Additional file 4: of Cost-effectiveness of healthy eating and/or physical activity promotion in pregnant women at increased risk of gestational diabetes mellitus: economic evaluation alongside the DALI study, a European multicenter randomized controlled trial
Creators: name: Broekhuizen, Karen
name: Simmons, David
name: Devlieger, Roland
name: van Assche, AndrĂŠ
name: Jans, Goele
name: Galjaard, Sander
name: Corcoy, Rosa
name: Adelantado, Juan
name: Dunne, Fidelma
name: Desoye, Gernot
name: Harreiter, JĂźrgen
name: Kautzky-Willer, Alexandra
name: Damm, Peter
name: Mathiesen, Elisabeth
name: Jensen, Dorte
name: Andersen, Liselotte
name: Lapolla, Annunziata
name: Dalfra, Maria
name: Bertolotto, Alessandra
name: Wender-Ozegowska, Ewa
name: Zawiejska, Agnieszka
name: Hill, David
name: Snoek, Frank
name: Jelsma, Judith
name: Bosmans, Judith
name: van Poppel, Mireille
name: van Dongen, Johanna
Publisher: name: figshare
Year: 2018
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: Results of the sensitivity analyses. (DOCX 116 kb)
Amtliche Mitteilungen der Technischen Universität Dortmund Nr. 6/2020
Creators: name: (:Unkn) Unknown
Publisher: name: Technische Universität Dortmund
Year: 2020
Subjects: subject: 080

description: Regeln guter wissenschaftlicher Praxis an der Technischen Universität Dortmund [Stand: 12.12.2019]
description: Amtliche Mitteilungen der Technischen Universität Dortmund;2020,6
Additional file 1: of Traditional Chinese medicine formula Bi-Qi capsule alleviates rheumatoid arthritis-induced inflammation, synovial hyperplasia, and cartilage destruction in rats
Creators: name: Wang, Kai
name: Zhang, Dongmei
name: Liu, Yan
name: Wang, Xuan
name: Zhao, Jiantong
name: Sun, Tingting
name: Jin, Tingting
name: Li, Baoli
name: Pathak, Janak
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine

description: Table S1. Physiological and behavioral observation. Table S2. Body weight. (DOCX 18 kb)
title: 02_1546
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Additional file 1: of Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice
Creators: name: Mei, Mei
name: Song, Haojun
name: Chen, Lina
name: Hu, Bin
name: Bai, Ru
name: Xu, Diandou
name: Liu, Ying
name: Zhao, Yuliang
name: Chen, Chunying
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Mental Health

description: Figure S1. mRNA expression in mouse lungs was detected 2Â days after exposure to PM by OA. Figure S2.Â PM induces oxidative stress in vitro and in vivo. Table S1. Primers used for quantitative real time PCR analysis. Table S2. The parameters involved in inflammatory responses with statistical difference between three size-fractionated ultrafine and fine atmospheric particulate matter groups in OVA-induced asthma model. (PDF 2041 kb)
Mujeres en la economía informal
Creators: name: Chamana, Rober
Publisher: name: figshare
Year: 2017
Subjects: subject: Gender studies
subject: 160512 Social Policy
subject: FOS: Political science

description: Análisis sobre la incorporación de la mujer en el mercado laboral en el Perú, desde una perspectiva de género.
An Open Source Technoscape in India: Motivations, Manifestations, and Speculations
Creators: name: Srinivasan, Sumitra
Publisher: name: Georgia State University
Year: 2006

description: My dissertation studies the political and corporate reasons behind the adoption of free and open source software technologies in a developing nation, India. This study also attempts to understand the significance of these grassroots technologies for India as it plays on a global arena.

How do ?free? and ?open source software? movements develop in an Indian context and bridge digital divides? The core of the first chapter will establish the questions investigated in this study as well as the significance of this interdisciplinary project for India.

It is also important to understand that the varied roles of governments and corporations supporting a new technology, are crucial to its success. Chapter 2 studies the motivations of the Indian government towards adopting free and open-source technologies.

The motivations of the industry are different from governmental motivations. In chapter 3, the landscape of Indian software industry players and their reasons for supporting these software technologies are discussed.

How do governmental and industry motivations translate? Are they successful and do they live up to their hype? Chapter 4 distinguishes between the hype and reality of the software landscape in India and presents a larger picture of the controversies surrounding software development, in general.

A concluding essay of chapter 5 couches the entire project within the process of globalization, speculating its significance for sustainable global information flows.
Scoping Population Health in Impact Assessment (ScopHIA) Realist Review: Identifying Best Practices for Equity in Scoping of Major Natural Resource and Large-Scale Infrastructure Projects
Creators: name: Brown, Jennifer Ann; Gorman, Melissa; Kim, Hyejun; Schober, Kelsey; Vipond, Joe; Nykiforuk, Candace
Publisher: name: University of Alberta Libraries
Year: 2020

Abstract
How Specific Resilience Pillars Mitigate the Impact of Drought on Food Security: Evidence from Uganda
Creators: name: Sunday, Nathan
name: Kahunde, Rehema
name: Atwine, Blessing
name: Adelaja, Adesoji
name: Kappiaruparampil, Justin
name: Sunday, Nathan
name: Kahunde, Rehema
name: Atwine, Blessing
name: Adelaja, Adesoji
name: Kappiaruparampil, Justin
Publisher: name: Unknown
Year: 2021
Subjects: subject: Agricultural and Food Policy
subject: drought
subject: resilience capacities
subject: food security

description: ABSTRACT Uganda continues to be prone to climate shocks especially drought which has adverse impact on food security. This paper studies household resilience capacities with special focus on how different resilience capacities mitigate the impact of drought on food security. The study follows the TANGO framework and two-step factor analysis to construct resilience capacity indexes. It employs a panel data from the Uganda National Panel Surveys (UNPS) undertaken between 2010/11 and 2018/19, spanning five waves. To minimize the bias arising from subjective self-reported drought shock, we introduce an objective measure of drought from the global SPEI database into the UNPS data. We also control for attrition bias by controlling for attrition hazard estimated from the attrition function. Our analysis reveals that households in Uganda exhibit significantly low and nearly static resilience capacities. This implies majority of households in Uganda remain highly susceptible food insecurity in the event of severe drought. The study shows that building resilience capacities is an effective way of protecting households from such devastating situation. In this regard, adaptive capacity is found to be the most effective in mitigating the effect of drought on food security. Transformative capacity and absorptive capacities possess limited mitigating power. Based on significant components from each of the capacities, we recommend investing in early warning systems and wide dissemination of climate related information to enhance preparedness adaptation, encouraging and supporting formation and sustainability of informal institutions at local levels, enhancing access to communal resources, improved infrastructure and agriculture extension services by the most vulnerable groups.
Freedom and Terror: President George W. Bush's Ideograph Use during his First Term
Creators: name: Valenzano III, Joseph
Publisher: name: Georgia State University
Year: 2006

description: This is a rhetorical study of President George W. Bush?s use of the - ideographic dialectic in his appeals for support for war in Afghanistan and Iraq, as well as reelection in 2004. I argue that President Bush?s use of the - dialectic in each case provided him with specific rhetorical resources that enhanced his ability to seek support from the four discourse communities that constitute the foreign policy public: unilateralists, multilateralists, regionalists and coalition builders. The terministic flexibility of the ideographic dialectic worked well enough to encourage meanings in each foreign policy discourse community that were consonant with that group?s worldview. This allowed Bush to appeal to the disparate groups and appear as though he advocated their desired policies, when in fact, he did not promote any specific policy. This project contributes to the theoretical understanding of the ideograph by complicating the concept of the public. Further, it adds credence to claims that the War on Terror is a never-ending war.
Additional file 2: of Death at no cost? Persons with no health insurance claims in the last year of life in Switzerland
Creators: name: Panczak, Radoslaw
name: von Wyl, Viktor
name: Reich, Oliver
name: Luta, Xhyljeta
name: Maessen, Maud
name: Stuck, Andreas
name: Berlin, Claudia
name: Schmidlin, Kurt
name: Goodman, David
name: Egger, Matthias
name: Clough-Gorr, Kerri
name: Zwahlen, Marcel
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Adjusted odds ratios (AOR) and their 95% confidence intervals (CI) of lack of health insurance claims across selected main causes of death. AORs from sex-stratified, multivariable logistic models with robust standard errors. Lack of CI indicates reference category (for instance CVD). There were no events (having no HIC) among females aged 19â 50 dying of mental and behavioural disorders. Abbreviations: CVD, cardiovascular diseases; Mental & behav., Mental and behavioural disorders; Nat., nationality; Civ., civil status at the time of death; Urb., level of urbanization; Lan., language region; Swiss-SEP, Swiss neighbourhood index of socioeconomic position [13]. Attribution of causes of death follows ICD-10 coding. (PDF 82Â kb)
The South Korean Mediascape: State, Civil Society and the Implications of Regional Political Economy for Cultural Transformation
Creators: name: Ryoo, Woongjae
Publisher: name: Georgia State University
Year: 2006

description: Globalization now receives as much or more attention as any concept in the academic lexicon. While scholars and pundits struggle to grasp its complex and varied worldwide manifestations, few researchers have yet focused on the South Korean media and its relationships with state and civil society, situated as it is within a complex political economic terrain. The role of agencies and institutions, especially state involvement in the media sector and in culture more broadly, has been controversial for communication scholars. In the last two decades a dramatic upsurge of neoliberal thinking has glorified the virtues of unregulated markets, and so-called ­øend-of-history­ñ discourse has ideologically championed incessant deregulation and economic and cultural privatization. Many neoliberalist scholars have argued that human nature and the structure of modern political, economic and cultural activities are such that the more constrained is the state, the better will be the quality and competitiveness of the more autonomous realms of enterprise and civil society. By contrast, my aim is to provide a fuller understanding of the political economy of a national/regional, as well as global mediascape, and to offer a more nuanced analysis of the role of the state and civil society in global and local cultural transformations, by careful attention to the case study of South Korea. Specifically, I examine interventions by the state and civil society in transforming the scene of national and global mediascapes, focusing on their various policies, regulations, movements and other initiatives. While it would be absurd to deny the pressures on semi-periphery by powerful international organizations (e.g., the IMF or WTO), these global constraints and pressures do not wholly dictate policy outcomes, whether economic or cultural, and globalization is not an inevitable nor omnipotent force that utterly deprives societies of their ability to maneuver when they must decide on policy. Hence development or social changes are negotiated in a manner more complex than typically acknowledged by globalization scholars (from the left or right), and in ways that aim to open up closed and inefficient institutions and reflect local social conditions and its needs, and sometimes succeed in doing so.
Lithospheric structures of the newer volcanics province, Western Victoria, Australia, from a long-period magnetotelluric method
Creators: name: Aivazpourporgou, Sahereh
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: In this thesis the magnetotelluric method is used to image the lithospheric structures of western Victoria and, particularly, to investigate previously identified teleseismic anomalies in the lithosphere and their possible relationship to magma genesis of the Newer Volcanic Province (NVP). An array of long-period MT data, consisting of 40 stations, has been collected in western Victoria over the same 270 km x 300 km grid of the previous teleseismic study. None of the traditional models of rifting, subduction and hot spot can adequately explain the distribution and age of volcanism. To constrain lithospheric temperatures, a 2D steady-state lithospheric thermal conduction model is developed based on the interpretation of a recent two-way-time deep seismic reflection survey conducted across the central and western Victorian Goldfields. This model predicts the temperature beneath the Stawell and Bendigo zones at the Moho (~40 km depth) is ~750°C and it increases to ~1200°C at ~80 km depth. This model shows that thermal refraction may perturb surface heat flow values across the Moyston Fault and the Heathcote Fault Zone. However, the paucity of heat flow data and poor understanding of geology at depth make the thermal conduction models highly sensitive and of limited use for constraining MT models. Forward modelling of MT data support the presence of a lithospheric conductor underneath the Central Highlands and the presence of an electrical conductivity contrast between the Delamerian and the Lachlan Orogens. In addition, forward models show the ocean has a strong effect on MT responses 50 km inland of the Victorian coastline and 130 km inland of the South Australian coastline, while the effect of the Otway basin is only significant within a distance of 30 km of the thickest sediment sequence. Results of 2D inversion modelling illustrate that there is a conductive zone (10-30 Ωm) underneath the Central Highlands at ~40-80 km depth that extends ~40-90 km NW-SE. The anomaly is consistent with the presence of 4-11% partial melting of lithospheric mantle in the presence of H2O (0.05-0.1%), supported by independent geochemistry studies on melting depths and degree of partial melting. Inversion results show the origin of the anomaly is not elevated temperature in a dry mantle due to a mantle plume beneath the NVP. Other possible causes considered include hydrous minerals, sulphides and high-Fe content, however, none produce conductivities of the anomaly on their own. The inversion models show that the melt is located within a “cavity” at the base of a younger thinner lithospheric mantle with oceanic origin neighbouring older thicker continental lithospheric mantle. The preferred model for magma genesis is by decompression melting caused by mantle upwelling of buoyant asthenosphere underneath this cavity. However, some water is required to reduce the mantle solidus.
title: Auto- and cross-regulation of the hnRNPs D and DL & Hypoxia-driven gene expression changes in human cancer cells
Creators: name: Fischer, Sandra
Publisher: name: UNSPECIFIED
Year: 2020

description: RNA-binding proteins (RBPs) control all steps of mRNA processing, including pre-mRNA splicing, mRNA localization, stability and translation efficiency. Auto- and cross-regulation of RBPs is essential for RBP homeostasis and the prevention of pathologies. Consequently, deregulation of RBPs is prevalent in diseases, in particular during tumorigenesis. A profound understanding of RBP regulation is thus indispensible to open up new approaches in cancer therapy. HnRNP DL is a ubiquitous RBP that is overexpressed in prostate cancer and chronic myeloid leukemia. HnRNP DL was suggested to regulate its own expression in a negative feedback loop via usage of a poison exon in its 3’ UTR. In this study, hnRNP DL autoregulation by binding to its own pre-mRNA was confirmed and cross-regulation between hnRNP DL and its well-studied paralog hnRNP D (AUF1) was demonstrated. Strikingly, hnRNP DL is a crucial factor for endothelial cell function, such as migration and angiogenesis. This highlights the influence of hnRNP DL, and RBPs in general, on cellular key processes. The cellular environment has an influence on the levels of RBPs and their functionality. Oxygen starvation (hypoxia) is a common cellular stress. It appears physiologically at high altitudes or during embryonic development, but hypoxia is also typical for diseased tissue. In particular in solid tumors, the hypoxic microenvironment influences gene expression and promotes cancerogenesis leading to poor patient outcomes. The transcriptional response to hypoxia is well studied and controlled by hypoxia inducible factor (HIF) proteins. However, the posttrancriptional response to hypoxia is still poorly understood. Thus, this study focused on hypoxia-driven changes in RBP levels and alternative splicing (AS) in human cancer cells. Transcriptome analyses showed correlated gene expression changes in human lung and breast cancer cells after chronic hypoxia treatment, but AS changes were highly divergent, demonstrating the cell type-specificity of AS. Strikingly, muscleblind-like 2 (MBNL2) was specifically induced under hypoxia, while RBPs were predominantly reduced. Subsequent transcriptome analyses after MBNL2 depletion showed that MBNL2 controls hypoxia-driven AS and the transcript abundance of typical hypoxia-induced genes, such as vascular endothelial growth factor (VEGFA). Strikingly, this control is specific for MBNL2 and not shared by its paralog MBNL1, showing the importance of MBNL2 for cancer cell adaptation to hypoxia. In addition, MBNL2 depletion led to reduced cancer cell proliferation and migration, indicating that deregulated RBPs might be new targets for cancer therapy.
title: 01_2110
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/