cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Cost-effectiveness analysis of trastuzumab emtansine for second-line treatment of HER2+ advanced breast cancer in Singapore
Creators: name: Wong, Wei Han Melvin
name: Ng, Raymond
name: Aziz, Mohamed Ismail Abdul
name: Ong, Benjamin Shao-Kiat
name: Ng, Kwong
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: To evaluate the cost-effectiveness of trastuzumab emtansine (T-DM1) compared to both lapatinib plus capecitabine (lapcap) and trastuzumab plus capecitabine (trascap) for treating human epidermal growth factor 2-positive advanced breast cancer patients, who have received prior treatment with trastuzumab and a taxane, in Singapore. A three-state partitioned survival model was used to evaluate the cost-effectiveness from the local healthcare system perspective. Key effectiveness data, including progression-free survival and overall survival from the pivotal EMILIA trial, were used alongside local clinician inputs. Health state utilities (in quality-adjusted life years [QALYs]) were obtained from the literature and direct medical costs obtained from the public health institutions in Singapore. Scenario, one-way, and probabilistic sensitivity analyses were conducted to explore the impact of uncertainties on cost-effectiveness. The base-case incremental cost-effectiveness ratios (ICERs) for T-DM1, compared to lapcap and trascap, were S$472,600 and S$495,200 per QALY gained, respectively. Sensitivity and scenario analyses showed high ICERs, with a 50% price reduction for T-DM1 resulting in an ICER above S$200,000. At current prices, T-DM1 is unlikely to be a cost-effective use of Singapore’s limited healthcare budget. These findings can help inform policymakers, alongside other considerations, on funding decisions.
Additional file 5 of Review of the target trial methodological approach on treatment effect estimates in kidney failure: protocol for a systematic assessment
Creators: name: Pinter, Jule
name: Tunnicliffe, David J.
name: Karunikaikumar, Pooshwikaa
name: Anastasiadis, Anastasios
name: Hills, Robert K.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 5: Search strategy.
Algorithm of Handling Out-of-Order Delivery for Multithreaded UDP-based Data Transport
Creators: name: Syzov, Dmytro
name: Kachan, Dmitry
name: Siemens, Eduard
Publisher: name: Hochschule Anhalt
Year: 2017
Subjects: subject: 000: Informatik, Wissen, Systeme
subject: 004: Datenverarbeitung, Informatik

description: Proceedings of 5th International Conference on Applied Innovations in IT / Prof. Dr. Siemens, Eduard (2017). Jg. 5, Köthen, 2017
description: As industry of information technologies evolves, demand for high speed data transmission steadily increases. The need in it can be found in variety of different industries – from entertainment with trends for increasing of video to scientific research. One of the consequences is a demand for new improved transport protocols that would use the capacity of Long Fat Pipes by maximum, where common TCP performs much slower than it is expected. Such protocols are mostly based on UDP and work at the user space. To improve their network throughput, there is an option to implement sending data in a multi-threading way, but that can bring complications with it. One of the main obstacles is a possibility of out-of-order delivery due to race conditions. This problem is researched in current paper. Causes of reorder are studied regarding UDP-based transport protocols. Based on the results of the testing, a simple algorithm for compensating out-of-order delivery is proposed. It's effect then is analysed on the example of RMDT.
Supplemental Material, Online_Supplemental_Content_File_1 - Use of Critical Items in Determining Point-of-Care Ultrasound Competence
Creators: name: Desy, Janeve
name: Noble, Vicki E.
name: Woo, Michael Y.
name: Walsh, Michael
name: Kirkpatrick, Andrew W.
name: Ma, Irene W. Y.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111099 Nursing not elsewhere classified
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental Material, Online_Supplemental_Content_File_1 for Use of Critical Items in Determining Point-of-Care Ultrasound Competence by Janeve Desy, Vicki E. Noble, Michael Y. Woo, Michael Walsh, Andrew W. Kirkpatrick and Irene W. Y. Ma in Evaluation & the Health Professions
Autologous stem-cell transplantation and maintenance therapy for transplant-eligible multiple myeloma patients: cost-effectiveness analysis based on a network meta-analysis
Creators: name: Wu, Weijia
name: Wang, Yannan
name: Lou, Yingting
name: Fan, Xiaoyuan
name: Yang, Wenqianzi
name: Tang, Fengyuan
name: Zhao, Zixuan
name: Dong, Hengjin
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: This study aimed to evaluate the cost-effectiveness of ASCT and maintenance therapy strategies for transplant-eligible patients with newly diagnosed multiple myeloma from a Chinese healthcare perspective. A short-run decision tree and a long-run Markov model were created to assess the mean costs and quality-adjusted life-years (QALYs) of ASCT plus maintenance therapy over a lifetime horizon. Utility values were sourced from published literature, while healthcare costs were based on a single-center retrospective analysis and national drug bidding data. The ASCT strategy with two-year daratumumab maintenance had the lowest discounted costs (1,394,183 CNY). Compared to no ASCT with continuous lenalidomide maintenance, ASCT had an ICER of 90,997 CNY/QALY. With one-year lenalidomide maintenance, ASCT provided more QALYs at lower costs. One-year lenalidomide maintenance after ASCT also resulted in higher QALYs and lower costs than no maintenance, while continuous lenalidomide had an ICER of 396,731 CNY/QALY. Under the WTP threshold of CNY 268,074 per QALY, ASCT strategies were more cost-effective than non-ASCT approaches. One-year lenalidomide therapy after ASCT was more cost-effective than no maintenance or continuous therapy. Among all strategies, ASCT followed by two years of daratumumab maintenance was the most cost-effective option.
sj-pdf-1-ene-10.1177_2514848620975342 - Supplemental material for Conflicts, cooperation and experimentation: Analysing the politics of urban water through Accra’s heterogeneous water supply infrastructure
Creators: name: Alba, Rossella
name: Kooy, Michelle
name: Bruns, Antje
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 120599 Urban and Regional Planning not elsewhere classified
subject: FOS: Social and economic geography

description: Supplemental material, sj-pdf-1-ene-10.1177_2514848620975342 for Conflicts, cooperation and experimentation: Analysing the politics of urban water through Accra’s heterogeneous water supply infrastructure by Rossella Alba, Michelle Kooy and Antje Bruns in EPE: Nature and Space
The impact of comprehensive public hospital reform on economic burden of inpatients with chronic obstructive pulmonary disease: evidence from a pilot city in western China
Creators: name: Wu, Yanghaotian
name: Qiu, Jingfu
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: The Chinese government launched a comprehensive reform of public hospitals, including a zero-markup drug policy (ZMDP) and adjustments to the price compensation mechanism for medical services. We aimed to assess the impact of the reform on economic burden for chronic obstructive pulmonary disease (COPD) inpatients. Health care institutions were selected using judgmental sampling. Structural variation analysis was conducted to assess changes in the cost structure. An interrupted time series analysis was used to evaluate level and trend changes in medical costs. After the reform, the total cost, western medicine cost, and traditional Chinese medicine cost per visit decreased significantly, with monthly downward trends (p < 0.05). The proportion of western medicine cost decreased by 5.59%, but remained the main composition (31.78%). The health insurance payments, out-of-pocket (OOP) cost per visit, and OOP cost proportion decreased significantly (p < 0.05). The health insurance payments per visit showed a monthly downward trend (p < 0.001), and the decline in OOP cost per visit extended (p = 0.003). The reform reduced the economic burden of COPD inpatients, optimized the cost structure and improved the efficiency of health insurance utilization. However, the short-term substitution effect of medical services on medicines weakened the cost-reduction effect.
Additional file 6 of Review of the target trial methodological approach on treatment effect estimates in kidney failure: protocol for a systematic assessment
Creators: name: Pinter, Jule
name: Tunnicliffe, David J.
name: Karunikaikumar, Pooshwikaa
name: Anastasiadis, Anastasios
name: Hills, Robert K.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 6: Adapted Appraisal Checklist [20, 22–24].
A cost-effectiveness estimation of the Attempted Suicide Short Intervention Programme (ASSIP)
Creators: name: Lelie, Max
name: Parmentier, Riet
name: de Jaegere, Eva
name: Simoens, Steven
name: Annemans, Lieven
name: Putman, Koen
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Biotechnology
Science Policy
Mental Health

description: Patients who have previously attempted suicide are at a substantially increased risk of a repeated attempt. We have conducted a cost-utility analysis of the Attempted Suicide Short Intervention Programme (ASSIP) and compared it with treatment as usual in a Flemish population. A closed-cohort Markov-model was used to simulate suicide over a time-horizon of 20 years in a cohort of prior suicide attempt patients. This model is used to estimate Incremental Cost Effectiveness Ratios (ICERs) from societal and healthcare perspectives. A separate ‘tipping-point’ scenario was included, where the treatment effectiveness regresses over time. ASSIP is shown to be a dominant strategy from the societal perspective and cost-effective from a healthcare perspective: the ICER after 10 years is € 1,133 and after 20 years € 304. In the tipping-point scenario, an regression of up to 82,7% after the intervention remains cost-effective, assuming an ICER threshold of € 44000 per QALY. Our study found that ASSIP is cost-effective in the Flemish region, saving both healthcare costs and societal expenses over time. Implementing ASSIP could provide significant economic and health benefits within 10 years, making it a valuable investment for improving mental health care.
Supplemental Material, sj-pdf-2-tva-10.1177_1524838020977161 - Traumatic Childbirth Experiences of New Parents: A Meta-Synthesis
Creators: name: Shorey, Shefaly
name: Wong, Phyllis Zhi En
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, sj-pdf-2-tva-10.1177_1524838020977161 for Traumatic Childbirth Experiences of New Parents: A Meta-Synthesis by Shefaly Shorey and Phyllis Zhi En Wong in Trauma, Violence, & Abuse
Perfil de ingreso de los estudiantes de la facultad de ciencias agrícolas en la universidad central del Ecuador
Creators: name: Millingalli, Jonathan
Publisher: name: unknown
Year: 2023

description: Desde que se implemento el bachillerato general unificado Y con esta el examen nacional de
educación superior también conocido como (ENES) se ha opinado del mismo tanto
académicamente como cotidianamente . las criterios sobre este son muy diversos entre
estudiantes Cómo padres y madres de familia teniendo en cuenta los gastos al puntaje
obtenido los temas abordados motivos y metas Qué se requiera cómo conseguir el proceso en
esto ensayo se aplicara como influye todas las factores antes mencionados a la hora de
ingresar de la facultad de ciencias agrícolas de la universidad central
description: Desde que se implemento el bachillerato general unificado Y con esta el examen nacional de educación superior también conocido como (ENES) se ha opinado del mismo tanto académicamente como cotidianamente . las criterios sobre este son muy diversos entre estudiantes Cómo padres y madres de familia teniendo en cuenta los gastos al puntaje obtenido los temas abordados motivos y metas Qué se requiera cómo conseguir el proceso en esto ensayo se aplicara como influye todas las factores antes mencionados a la hora de ingresar de la facultad de ciencias agrícolas de la universidad central
E00726: Victricius of Rouen lists the relics of saints already present in Rouen: *John the Baptist (S00020), the Apostles *Andrew (S00289) and *Thomas (S00199), *Gervasius and Protasius (martyrs of Milan, S00313), *Agricola (martyr of Bologna, S00310), *Euphemia (martyr of Chalcedon, S00017), and *Luke (the Evangelist, S00442). Account in Victricius' Praising the Saints, written in Latin, c.396 in Rouen (northern Gaul).
Creators: name: Mtycner
Publisher: name: University of Oxford
Year: 2015
Subjects: History

description: Victricius of Rouen, Praising the Saints 6

For a summary and discussion of the whole text, see E00717.

Victricius addresses the relics of saints sent to him from Milan, and tells them of the saints they will already find within the city (lines 32-37):

Hic inuenietis Iohannem Baptistam, illum, inquam, qui in stadio communi cruentus stetit, sed ad caelum coronatus ascendit, quem Dominus ipse inter natos mulierum autumat potiorem. Hic Andream, hic Thomam, hic Geruasium, hic Protasium, hic Agricolam, hic Eufemiam, quae quondam masculato animo sub percussore uirgo non palluit.

'You will find here John the Baptist, he, I say, who stood bloodstained in the common arena, but ascended crowned to heaven, he whom the Lord himself names as greatest among those born of women. Here you will find Andrew, here Thomas, here Gervasius, here Protasius, here Agricola, here Euphemia, who once, her soul made masculine, did not, though a virgin, pale before the executioner.'

Later in the chapter (lines 53-60) Victricius continues his address to the new saints:

A uobis ad uos uenistis. Hic reperietis quos circa Domini Iesu Christi altaria ministrantes. Porrectis brachiis uos Baptista Iohannes expectat. Vos Thomas, uos Andreas, Lucas et cetera multitudo caelestis parili uos desiderio in suum gremium uocat. Nullus uos nouus hospes excipiet. Hi sunt cum quibus militatis in caelo. Peculiaris tamen erit gratulatio, si iungantur reliquiis, qui sunt iuncti claritudine spiritali.

'You have come from yourselves to yourselves. Here you will find those you left ministering at the altars of the Lord Jesus Christ. John the Baptist waits for you with arms outstretched. Thomas, Andrew, Luke, and all the heavenly multitude call you to their embrace with equal longing. It is no new host who will receive you: these are they with whom you are soldiers in heaven. But there will be special thanksgiving if those who are joined in spiritual light are joined in relics.'

Text: Mulders and Demeulenaere 1985, 78-79. Translation: Clark 1999, 383-4.
Additional file 1 of Antioxidants and the risk of stroke: results from NHANES and two-sample Mendelian randomization study
Creators: name: Chen, Rundong
name: Liu, Hanchen
name: Zhang, Guanghao
name: Zhang, Qian
name: Hua, Weilong
name: Zhang, Lei
name: Lv, Nan
name: Zhang, Yilei
name: Dai, Dongwei
name: Zhao, Rui
name: Li, Qiang
name: Huang, Qinghai
name: Xu, Yi
name: Yang, Pengfei
name: Liu, Jianmin
name: Zuo, Qiao
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Environmental Sciences not elsewhere classified
Science Policy

description: Additional file 1. ISGC Intracranial Aneurysm Working Group Contributors
Perfil de ingreso de los estudiantes de la facultad de ciencias agrícolas en la universidad central del Ecuador
Creators: name: Millingalli, Jonathan
Publisher: name: Humanities Commons
Year: 2023

description: Desde que se implemento el bachillerato general unificado Y con esta el examen nacional de educación superior también conocido como (ENES) se ha opinado del mismo tanto académicamente como cotidianamente . las criterios sobre este son muy diversos entre estudiantes Cómo padres y madres de familia teniendo en cuenta los gastos al puntaje obtenido los temas abordados motivos y metas Qué se requiera cómo conseguir el proceso en esto ensayo se aplicara como influye todas las factores antes mencionados a la hora de ingresar de la facultad de ciencias agrícolas de la universidad central
Supplemental Material, Appendix_B - Traumatic Childbirth Experiences of New Parents: A Meta-Synthesis
Creators: name: Shorey, Shefaly
name: Wong, Phyllis Zhi En
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, Appendix_B for Traumatic Childbirth Experiences of New Parents: A Meta-Synthesis by Shefaly Shorey and Phyllis Zhi En Wong in Trauma, Violence, & Abuse
E00728: Greek inscription on the capital of a column found near Magnesia ad Sipylum (province of Asia, western Asia Minor) with names of *Sergios (soldier and martyr of Rusafa, S00023) and *Bakchos (soldier and martyr of Barbalissos, S00079). Probably late antique (5th-8th c.).
Creators: name: Pnowakowski
Publisher: name: University of Oxford
Year: 2015
Subjects: History

description: Σεργίου καὶ Βάκχ[ου]

'Of Sergios and Bakchos.'

Text: TAM V/2, no. 1394.
E00730: Greek inscription on a capital found at Doğu Çamlik on the island of Prokonnesos (Sea of Marmara) with a dedication to *Mary (Mother of Christ, S00033). Tentatively dated stylistically to the Theodosian period (late 4th - earlier 5th c.).
Creators: name: Pnowakowski
Publisher: name: University of Oxford
Year: 2015
Subjects: History

description: Θ(εο)τ(όκ)ῳ τοῦ [- - -]

'For (? the church of) the Theotokos of the [- - -]'

Text: Asgari, Drew-Bear 2002, no. 40.
Additional file 2 of Antioxidants and the risk of stroke: results from NHANES and two-sample Mendelian randomization study
Creators: name: Chen, Rundong
name: Liu, Hanchen
name: Zhang, Guanghao
name: Zhang, Qian
name: Hua, Weilong
name: Zhang, Lei
name: Lv, Nan
name: Zhang, Yilei
name: Dai, Dongwei
name: Zhao, Rui
name: Li, Qiang
name: Huang, Qinghai
name: Xu, Yi
name: Yang, Pengfei
name: Liu, Jianmin
name: Zuo, Qiao
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Environmental Sciences not elsewhere classified
Science Policy

description: Additional file 2: Supplementary Figures and Tables. Figure S1. Flow chart of eligible National Health and Nutrition Examination Survey (NHANES) participants included in this study. Table S1. Diagnostic criteria of covariates in NHANES. Figure S2. The research is based on three hypotheses: (1) The instrumental variable is strongly correlated with diet-derived antioxidants; (2) The instrumental variable is not correlated with the confounding factors; (3) The instrumental variable is not directly related to stroke, and its effect on stroke can only be through diet-derived antioxidants to reflect. Table S2. The GWAS summary information of dietary-derived antioxidantsm [1, 2] and stroke [3-5]. Table S3. Categorize the CDAI by quartiles. Table S4. Association of vitamin A and stroke. Table S5. Association of vitamin C and stroke. Table S6. Association of vitamin E and stroke. Table S7. Association of zinc and stroke. Table S8. Association of selenium and stroke. Table S9. Association of carotenoid and stroke. Table S10. Genetic instrumental variables for dietary-derived antioxidants. Table S11. Associations between genetically predicted increase in dietary-derived antioxidants and stroke in Mendelian Randomization analyses. Table S12. Sensitivity analysis of antioxidants on stroke. Figure S3. Results of leave-one-out sensitivity analysis for Vitamin A on SAH. Figure S4. Results of leave-one-out sensitivity analysis for Selenium on SAH.
Supplemental Material, sj-docx-4-crd-10.1177_1479973120948077 - Randomised controlled trial of the effect, cost and acceptability of a bronchiectasis self-management intervention
Creators: name: Brockwell, Claire
name: Stockl, Andrea
name: Clark, Allan
name: Barton, Garry
name: Pasteur, Mark
name: Fleetcroft, Robert
name: Hill, Janice
name: Wilson, Andrew M
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: Supplemental Material, sj-docx-4-crd-10.1177_1479973120948077 for Randomised controlled trial of the effect, cost and acceptability of a bronchiectasis self-management intervention by Claire Brockwell, Andrea Stockl, Allan Clark, Garry Barton, Mark Pasteur, Robert Fleetcroft, Janice Hill and Andrew M Wilson in Chronic Respiratory Disease
Additional file 7 of Review of the target trial methodological approach on treatment effect estimates in kidney failure: protocol for a systematic assessment
Creators: name: Pinter, Jule
name: Tunnicliffe, David J.
name: Karunikaikumar, Pooshwikaa
name: Anastasiadis, Anastasios
name: Hills, Robert K.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 7.
E00731: Greek supply order from the Oxyrhynchite nome (Middle Egypt) concerning wheat and vegetable seed for the shrine of a local martyr, perhaps Apa *Taurine (S02678), providing a precise date on the document, 14 August 398.
Creators: name: Dlambert
Publisher: name: University of Oxford
Year: 2015
Subjects: History

description: P.Haun. 3 67, lines 1–3:

Φιλέας.
παράσχου εἰς τὰ ἅγια μαρτυρα ἄπα Τ̣[ ̣] ̣ ̣ ̣ ̣ σίτου ἀρτάβας ὀκτώ, λαχανο-
σπέρμου ἀρτάβας δύο, (γίνονται) σίτ(ου) (ἀρτάβας) η, λαχ(ανοσπέρμου) (ἀρτάβας) β. μ(όνας)

(r.2. l. μαρτύρα)

'(Order from) Phileas:
Deliver to the holy martyr shrine of Apa T … eight artabas of wheat (and) two artabas of vegetable seed. (Makes in total) 8 artabas of wheat, 2 artabas of vegetable seed.'

(Trans. Gesa Schenke)

The full record is available online at: http://papyri.info/ddbdp/p.haun;3;67
The IPUMS Business Process Model: Instituting a workflow mapping strategy to support archival processes
Creators: name: Magnuson, Diana L.
Publisher: name: Zenodo
Year: 2024

description: IPUMS is the home of the world's largest accessible database of census microdata, comprising over two billion records. The signature activity of IPUMS is harmonizing variable codes and documentation to be fully consistent across datasets. Major data types include U.S. and international censuses, global health data, major U.S. demographic surveys, labor force surveys, and educational surveys. In addition to census and survey microdata, IPUMS integrates and disseminates area-level census data and electronic boundaries describing census geography for the U.S. and internationally. While the activities of harmonizing data and documentation are similar across IPUMS projects, their processes are organized around the partners, data sources, unique content issues, and timelines of each project.The IPUMS Archive is instituting a workflow mapping strategy to further identify IPUMS process and metadata capture points for the data archive. Drawing on two business process models, the Generic Statistical Business Process Model (GSBPM) and the Generic Longitudinal Business Process Model (GLBPM), archival staff customized the GSBPM and the GLBPM to create an IPUMS Business Process Model (IPUMS BPM). The IPUMS BPM reflects the use of secondary data sources and the work of harmonization and integration to create a data infrastructure that supports research across time and space. Internally, the IPUMS BPM provides a clear visualization of our workflow from external submission of data, harmonization process, extraction systems, and archival preservation of metadata. The challenge for archival staff is furthering the understanding and adoption of the IPUMS BPM within the IPUMS project groups, and to identify metadata production points that requires the intervention of the archive for provenance and preservation purposes. This presentation identifies the value of this mapping approach in gaining a clearer understanding of the role of the archive within project work cycles and points where activities intersect.
Autologous Stem-cell Transplantation and Maintenance Therapy for Transplant-eligible Multiple Myeloma Patients: Cost-Effectiveness Analysis Based on a Network Meta-analysis
Creators: name: Wu, Weijia
name: Wang, Yannan
name: Lou, Yingting
name: Fan, Xiaoyuan
name: Yang, Wenqianzi
name: Tang, Fengyuan
name: Zhao, Zixuan
name: Dong, Hengjin
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: This study aimed to evaluate the cost-effectiveness of ASCT and maintenance therapy strategies for transplant-eligible patients with newly diagnosed multiple myeloma from a Chinese healthcare perspective. A short-run decision tree and a long-run Markov model were created to assess the mean costs and quality-adjusted life-years (QALYs) of ASCT plus maintenance therapy over a lifetime horizon. Utility values were sourced from published literature, while healthcare costs were based on a single-center retrospective analysis and national drug bidding data. The ASCT strategy with two-year daratumumab maintenance had the lowest discounted costs (1,394,183 CNY). Compared to no ASCT with continuous lenalidomide maintenance, ASCT had an ICER of 90,997 CNY/QALY. With one-year lenalidomide maintenance, ASCT provided more QALYs at lower costs. One-year lenalidomide maintenance after ASCT also resulted in higher QALYs and lower costs than no maintenance, while continuous lenalidomide had an ICER of 396,731 CNY/QALY. Under the WTP threshold of CNY 268,074 per QALY, ASCT strategies were more cost-effective than non-ASCT approaches. One-year lenalidomide therapy after ASCT was more cost-effective than no maintenance or continuous therapy. Among all strategies, ASCT followed by two years of daratumumab maintenance was the most cost-effective option.
Additional file 3 of Evaluation of a novel technology-supported fall prevention intervention – study protocol of a multi-centre randomised controlled trial in older adults at increased risk of falls
Creators: name: Morat, Tobias
name: Snyders, Melina
name: Kroeber, Philipp
name: De Luca, Alice
name: Squeri, Valentina
name: Hochheim, Martin
name: Ramm, Philipp
name: Breitkopf, Annika
name: Hollmann, Michael
name: Zijlstra, Wiebren
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Biotechnology
Computational Biology

description: Additional file 3. Number of deficits and their colours during the Silver Index (SI) Measurement and information about how to go on for exercise planning using these characteristics (C = case).
Psychometric properties of outcome measures for freezing of gait in Parkinson’s disease: a systematic review and meta-analysis
Creators: name: Proietti, Prisca
name: Ruotolo, Ilaria
name: Carlizza, Alessandra
name: Ugolini, Alessandro
name: Galeoto, Giovanni
name: Fabbrini, Giovanni
name: Sellitto, Giovanni
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Science Policy

description: This systematic review and meta-analysis evaluated validated tools for assessing FOG in PD, focusing on their psychometric properties, linguistic adaptations, and methodological quality. A systematic search was conducted in MEDLINE, CINAHL, SCOPUS, and Web of Science, following PRISMA-COSMIN guidelines. Studies assessing validity, reliability, and cross-cultural adaptation of FOG-specific tools were included. Key psychometric properties, such as internal consistency (Cronbach’s alpha) and test–retest reliability (Intraclass Correlation Coefficient, ICC), were extracted. The COSMIN Risk of Bias checklist was used to assess methodological quality, and meta-analyses were performed for comparable studies. Six validated tools were identified, with FOG-Q and NFOG-Q emerging as the most robust. Meta-analysis showed high internal consistency (FOG-Q: α = 0.90; NFOG-Q: α = 0.87–0.89) and test–retest reliability (FOG-Q ICC = 0.87), though substantial heterogeneity was noted (I² = 71.1–86.4%). Emerging tools, including CFOG-Q, Ziegler test, and DYPAGS, addressed cognitive and dual-tasking aspects but lacked linguistic validation. FOG-Q and NFOG-Q remain widely used, yet NFOG-Q may have limitations in detecting small clinical changes. Broader linguistic adaptations are needed, and emerging tools hold promise for multidimensional assessment. Future research should integrate subjective and objective measures for comprehensive evaluations. PROSPERO (CRD42020173873).
Perfil de ingreso de los estudiantes de la facultad de Ciencias Agrícolas en la Universidad Central del Ecuador
Creators: name: Pallo, Dennis
Publisher: name: unknown
Year: 2023

description: En este artículo se estudia el perfil de ingreso de los estudiantes a la Facultad de Ciencias Agrícolas en la Universidad Central del Ecuador, mediante el análisis de las estrategias, motivos y enfoques de aprendizaje que modelan el comportamiento del estudiante e influyen en su desempeño. No se encontró ninguna relación relevante entre el enfoque de aprendizaje y los factores extracurriculares; sin embargo, los estudiantes con padres con el mayor nivel educativo presentan el mayor enfoque superficial.
Additional file 1 of Perspective matters in recovery: the views of persons with severe mental illness, family and mental health professionals on collaboration during recovery, a qualitative study
Creators: name: Burger, Thijs J.
name: van Eck, Robin M.
name: Lachmeijer, Marjolein
name: de Wilde-Schutten, Kimriek R. G.
name: Lansen, Mette
name: van Alphen, Carola
name: van Haasteren, Niek
name: Groen, Karin
name: Schirmbeck, Frederike
name: Vellinga, Astrid
name: Kikkert, Martijn J.
name: Dekker, Jack
name: de Haan, Lieuwe
name: de Koning, Mariken B.
Publisher: name: figshare
Year: 2024
Subjects: Science Policy
Mental Health

description: Additional file 1. Topic guide.
Additional file 2 of Evaluation of a novel technology-supported fall prevention intervention – study protocol of a multi-centre randomised controlled trial in older adults at increased risk of falls
Creators: name: Morat, Tobias
name: Snyders, Melina
name: Kroeber, Philipp
name: De Luca, Alice
name: Squeri, Valentina
name: Hochheim, Martin
name: Ramm, Philipp
name: Breitkopf, Annika
name: Hollmann, Michael
name: Zijlstra, Wiebren
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Biotechnology
Computational Biology

description: Additional file 2. Details of the setting for planning and implementing the training sessions using the hunova robot regarding number of deficits, number of suggested training dimensions, dimensions, number of exercises, and duration of the training session.
Evaluating the accuracy of extrapolated overall survival for pembrolizumab: a comparison with long-term observed data in the Australian reimbursement context
Creators: name: Dehle, Francis C.
name: Phan, Kevin
name: Higgins, Jerome
name: Applegarth, Kate
name: Gambhir, Manoj
name: Taylor, Colman B.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Science Policy

description: Decisions about government funding for new medicines often rely on statistical models to predict how long patients will live (overall survival, OS) based on early trial data. This study compared the accuracy of these predictions for the cancer drug pembrolizumab, using models preferred by pharmaceutical companies (Sponsors) and the Pharmaceutical Benefits Advisory Committee (PBAC), compared to real-world long-term follow-up (LTFU) data. We reviewed publicly available PBAC summary documents (PSDs) for all funding decisions on pembrolizumab up to November 2022. We included cases with at least three years of follow-up data and where at least 350 patients per year would be treated. We then compared survival predictions from PBAC and Sponsor models to actual survival data at two time points. A total over 38 PSDs covering 15 indications, five met our criteria. Sponsor-preferred models underestimated real survival by 0.54% to 16.45%, while PBAC-preferred models underestimated survival by 1.20% to 24.21%. Results demonstrate that OS extrapolation methods used by both the Sponsor and PBAC tend to underestimate long-term survival outcomes for pembrolizumab indications, with PBAC-preferred methods being more conservative.
Additional file 1 of Efficacy of rTMS for poststroke epilepsy and its effects on patients’ cognitive function and depressive status
Creators: name: Hu, Minting
name: Qin, Bailing
name: Li, Tong
name: Wei, Chunyan
name: Su, Dajing
name: Tan, Zuocai
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Hematology

description: Supplementary Material 1
Comprehensive economic value evaluation of adding tislelizumab to first-line chemotherapy for patients with extensive-stage small cell lung cancer in China
Creators: name: Zhao, Shan
name: Kang, Shuo
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: The cost-effectiveness of tislelizumab plus chemotherapy for patients with extensive-stage small cell lung cancer (ES-SCLC) was uncleared yet. The current analysis aimed to evaluate the cost-effective of adding tislelizumab to the first-line chemotherapy for patients with untreated ES-SCLC from the Chinese health-care system perspective. A partitioned survival model that simulated 3-week patients transition in 10-year time horizon was established to evaluate the economic value. The clinical benefit and safety data were gathered from the RATIONALE-312 trial, model parameters were gathered from the local charges and previously published studies. Sensitivity analyses and subgroup analyses were conducted to examine the robustness of the model outcomes. Tislelizumab plus chemotherapy could bring additional 0.61 LYs and 0.30 QALYs with the marginal cost of $5,849.40, resulting in the incremental cost-effectiveness ratio (ICER) of $19,592.08 per additional quality-adjusted life-years (QALYs) gained. Sensitivity analyses and subgroup analyses confirmed the robustness of the model results for both intention-to-treat patients and all subgroup patients. Tislelizumab plus chemotherapy could be considered cost-effective first-line therapy for patients with untreated ES-SCLC patients compared with chemotherapy alone from the perspective of Chinese health-care system.
ДИФАМАЦІЙНІ ПРАВОВІДНОСИНИ І РЕПУТАЦІЯ СУДДІ У КОНТЕКСТІ ЗАВДАННЯ ЗМІЦНЕННЯ АВТОРИТЕТУ СУДОВОЇ ВЛАДИ
Creators: name: Головко, К. В.
Publisher: name: Zenodo
Year: 2024
Subjects: судова влада, правосуддя, суддя, репутація, безпека і незалежність судді, ділова репутація фізичної особи, ділова репутація юридичної особи, імідж, гудвіл

description: У даній статті досліджено дифамаційні правовідносини і захист репутації судді у контексті завдання зміцнення авторитету судової влади. Досліджуються питання, пов’язані зі змістом юридичної категорії «репутація» в рамках інституту дифамації, аналізується нормативно-правове врегулювання ділової репутації як об’єкту правового захисту, аналізується ділова репутація фізичної особи, ділова репутація юридичної особи та система її складових елементів, визначається співвідношення поняття «ділова репутація» із суміжними категоріями, такими як: «імідж», «гудвіл». Доведено, що дифамація суттєво впливає на репутацію суддів, що, у свою чергу, впливає на авторитет судової влади в цілому. У зв'язку з цим, захист честі, гідності та ділової репутації суддів є важливим завданням, яке потребує ефективних правових механізмів та чіткого законодавчого регулювання. В умовах інформаційного суспільства поширення недостовірної інформації може завдавати значної шкоди не лише окремим суддям, але й всій судовій системі. Встановлення чітких меж між допустимою критикою та дифамацією є важливим кроком для забезпечення балансу між правом на свободу вираження думок та необхідністю захисту репутації суддів.
Melody for Sunsets and Tides
Creators: name: Julian, June
Publisher: name: unknown
Year: 1989
Subjects: subject: Music
subject: Music
subject: Watercolor painting
subject: Contemporary music
subject: Art
subject: Mexico--Mazatlán (Sinaloa)
subject: Handmade paper

description: In June Julian's Melody for Sunsets and Tides painting series, her seascapes can be viewed as art and also can be played as musical notes. Consisting of five watercolors on handmade paper, each horizon line in each individual image corresponds to one of the notes on a musical staff, and can be sung or played by a musician.
Supplemental Material, Appendix_Body_Size_Social_Judgment - How Body Size Cues Judgments on Person Perception Dimensions
Creators: name: Bryksina, Olya
name: Luming Wang
name: Mai-McManus, Trang
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental Material, Appendix_Body_Size_Social_Judgment for How Body Size Cues Judgments on Person Perception Dimensions by Olya Bryksina, Luming Wang and Trang Mai-McManus in Social Psychological and Personality Science
Providing of QoS-Enabled Flows in SDN : Exemplified by VoIP Traffic
Creators: name: Ohms, Jannis
name: Kotelnikova, Nadiia
name: Wermser, Diederich
name: Siemens, Eduard
Publisher: name: Hochschule Anhalt
Year: 2017
Subjects: subject: 000: Informatik, Wissen, Systeme
subject: 004: Datenverarbeitung, Informatik

description: Proceedings of 5th International Conference on Applied Innovations in IT / Prof. Dr. Siemens, Eduard (2017). Jg. 5, Köthen, 2017
description: This paper provides a proof of concept of an SDN Application to provide QoS for real-time services on SDN networks. Common real-time services are for example VoIP or M2M protocols like OPC UA and MQTT. We provide a proof of concept in the form of a specialized application for SIP traffic. The application lowers the latency and call-setup-time for VoIP calls. The application uses the metering and queueing features of OpenFlow 1.3 to assure high quality of service. The evaluation and optimization of the application is still in progress.
Melody for Sunsets and Tides
Creators: name: Julian, June
Publisher: name: Humanities Commons
Year: 1989
Subjects: subject: Music
subject: Art
subject: Watercolor painting
subject: Handmade paper
subject: Mexico--Mazatlán (Sinaloa)
subject: Contemporary music

description: In June Julian's Melody for Sunsets and Tides painting series, her seascapes can be viewed as art and also can be played as musical notes. Consisting of five watercolors on handmade paper, each horizon line in each individual image corresponds to one of the notes on a musical staff, and can be sung or played by a musician.
Patient-relevance of outcome measures in breast cancer clinical trials: a cross-sectional comparative analysis of patient preferences and trials conducted between 2014 and 2024
Creators: name: Plooij, Jasmijn
name: Delnoij, Diana M.J.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Pharmacology
Biotechnology
Cancer
Science Policy

description: Worldwide, many clinical trials are performed using clinical outcomes and surrogate outcomes as endpoints. Surrogate outcomes are used, for instance, if there is not enough follow-up time to measure the outcome of interest. Surrogate outcomes might not be patient-relevant, however. This study assesses to what extent patient-relevant outcomes are measured in clinical trials for breast cancer drugs. A cross-sectional comparative analysis was conducted in which patient preferences for outcomes derived from the literature were compared to outcomes measured in phase III breast cancer trials conducted between 2014 and 2024. Patients prefer outcomes addressing survival benefits, treatment effectiveness, adverse events and health-related quality of life. Minor improvements in survival benefits are greatly valued. The majority of patients are willing to accept some side effects for a positive outcome. The primary outcome used most frequently in trials is progression-free survival. The most common secondary outcomes are adverse events, mortality, overall response rate, and health-related quality of life. Phase III trial outcomes appear to align largely with breast cancer patients’ preferences. Nevertheless, patients and trial designers emphasize different outcomes. Improvement is therefore needed to enhance the relevance of trial data for patients.
E00732: Two Greek receipts probably from the Herakleopolite nome (Middle Egypt), mentioning a presbyter and oikonomos of an institution dedicated to Apa *Isaac (ob. 4th cent.), datable to the 6th/7th c.
Creators: name: Gschenke
Publisher: name: University of Oxford
Year: 2015
Subjects: History

description: P.Lugd. Bat. 19 23, lines 3–6:

 παρὰ σοῦ̣ υἱος
 Ἄνι πρεσβ(υτέρου) ἠκωνόμου το̣ῦ̣ ἁγίου
5 ἄπα Ἰσαὰκ (ὑπὲρ) σηνεθία̣(ς) ἀρουρ(ῶν)
 ἡμῶν.

'… From you, son of Ani, presbyter and oikonomos of saint Apa Isaak, for the customer repayment of our arouras.'

(Text and trans.: E. Boswinkel and P.W. Pestman)

The full record with image is available online at: http://papyri.info/ddbdp/p.batav;;23/

SPP III 24 Rekto = P.Lugd. Bat. 19 23 bis, lines 3–6:

 παρὰ σ̣[οῦ]
 τοῦ υἱος Ἀάνι πρε(σβυτέρου) ἠκωνόμου̣
5 τοῦ ἁγίου ἄπα Ἰσαὰκ (ὑπὲρ) συνηθια
 ἀρουρ(ῶν) ἡμῶν.

'… From you, son of Ani, presbyter and oikonomos of saint Apa Isaak, for the customer repayment of our arouras.'

(Text and trans.: E. Boswinkel and P. W. Pestman)

The full record with image is available online at: http://papyri.info/ddbdp/p.batav;;23bis/
sj-pdf-3-gam-10.1177_2164956120964712 - Supplemental material for A 4-Month Whole-Systems Ayurvedic Medicine Nutrition and Lifestyle Intervention Is Feasible and Acceptable for Breast Cancer Survivors: Results of a Single-Arm Pilot Clinical Trial
Creators: name: Dhruva, Anand
name: Wu, Cairn
name: Miaskowski, Christine
name: Hartogensis, Wendy
name: Rugo, Hope S
name: Adler, Shelley R
name: Kaptchuk, Ted J
name: Rucha Kelkar
name: Agarawal, Sangeeta
name: Amisha Vadodaria
name: Garris, Ellen
name: Hecht, Frederick M
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Medicine
subject: 111799 Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-pdf-3-gam-10.1177_2164956120964712 for A 4-Month Whole-Systems Ayurvedic Medicine Nutrition and Lifestyle Intervention Is Feasible and Acceptable for Breast Cancer Survivors: Results of a Single-Arm Pilot Clinical Trial by Anand Dhruva MD Cairn Wu BA Christine Miaskowski RN, PhD Wendy Hartogensis Phd, MPH Hope S Rugo MD Shelley R Adler PhD Ted J Kaptchuk, Rucha Kelkar BAMS, PT, DPT Sangeeta Agarawal RN, MS, CAS Amisha Vadodaria BA Ellen Garris CAS Frederick M Hecht MD in Global Advances in Health and Medicine
Perfil de ingreso de los estudiantes a la Facultad de Ciencias Agrícolas en la Universidad Central del Ecuador
Creators: name: Carvajal, Daniel
Publisher: name: unknown
Year: 2023

description: El perfil de ingreso de estudiantes es importante para garantizar la excelencia en la educación y formación de futuros agrónomos, existen requisitos para garantizar el ingreso de estudiantes que sean capaces, y posean las habilidades necesarias para destacarse en el futuro campo laboral. Un estudiante debe considerar la motivación y los objetivos que espera alcanzar, ademas de las estrategias y los recursos cognitivos necesarios para alcanzar los objetivos. Por tanto, cabe señalar que el aprendizaje está directamente relacionado con los aspectos cognitivos, emocionales, psicológicos y conductuales de los estudiantes.
Perfil de ingreso de los estudiantes a la Facultad de Ciencias Agrícolas en la Universidad Central del Ecuador
Creators: name: Carvajal, Daniel
Publisher: name: Humanities Commons
Year: 2023

description: El perfil de ingreso de estudiantes es importante para garantizar la excelencia en la educación y formación de futuros agrónomos, existen requisitos para garantizar el ingreso de estudiantes que sean capaces, y posean las habilidades necesarias para destacarse en el futuro campo laboral. Un estudiante debe considerar la motivación y los objetivos que espera alcanzar, ademas de las estrategias y los recursos cognitivos necesarios para alcanzar los objetivos. Por tanto, cabe señalar que el aprendizaje está directamente relacionado con los aspectos cognitivos, emocionales, psicológicos y conductuales de los estudiantes.
Additional file 1 of Barriers and facilitators to fulfilling the teaching assistant role from nursing students’ perspective: a qualitative study
Creators: name: Pashaeypoor, Shahzad
name: Majdabadi, Zahra Amrollah
name: Khanipour-Kencha, Ali
name: Nikpeyma, Nasrin
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Science Policy
Mental Health

description: Additional file 1.
Public art at Campbelltown brightens up the Queen Street precinct
Creators: name: Willis, Ian
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Australia
subject: New South Wales
subject: New South Wales--Campbelltown
subject: Public art spaces

description: Keep your eyes open in central Campbelltown for inspiring public art installations that brighten up dull spaces around the town. The Campbelltown Arts Centre, in conjunction with Campbelltown City Council and the NSW Government, have a program to re-invigorate the city centre using public art.