cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Composite Vector Leptoquarks in $e^+ e^-$, $γe$, and $γγ$ Colliders
Creators: name: Montalvo, J. E. Cieza
name: Eboli, O. J. P.
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the signals for composite vector leptoquarks in $e^+ e^-$ colliders (LEP II, NLC, and CLIC) through their effects on the production of jet pairs, as well as their single and pair productions. We also analyze their production in $γe$ and $γγ$ collisions.
description: revtex, 17 pages and 8 figures (available upon request), IC/92/156
A security approach based on honeypots: Protecting Online Social network from malicious profiles
Creators: name: Elmendili, Fatna
name: Maqran, Nisrine
name: Idrissi, Younes El Bouzekri El
name: Chaoui, Habiba
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: In the recent years, the fast development and the exponential utilization of social networks have prompted an expansion of social Computing. In social networks users are interconnected by edges or links, where Facebook, twitter, LinkedIn are most popular social networks websites. Due to the growing popularity of these sites they serve as a target for cyber criminality and attacks. It is mostly based on how users are using these sites like Twitter and others. Attackers can easily access and gather personal and sensitive users information. Users are less aware and least concerned about the security setting. And they easily become victim of identity breach. To detect malicious users or fake profiles different techniques have been proposed like our approach which is based on the use of social honeypots to discover malicious profiles in it. Inspired by security researchers who used honeypots to observe and analyze malicious activity in the networks, this method uses social honeypots to trap malicious users. The two key elements of the approach are: (1) The deployment of social honeypots for harvesting information of malicious profiles. (2) Analysis of the characteristics of these malicious profiles and those of deployed honeypots for creating classifiers that allow to filter the existing profiles and monitor the new profiles.
description: 7 PAGES 10 FIGURES
An iboga alkaloid chemotaxonomic marker from endemic Tabernaemontana ternifolia with antitubercular activity
Creators: name: Garcellano, Rhea C.
name: Cort, John R.
name: Moinuddin, Syed G. A.
name: Franzblau, Scott G.
name: Ma, Rui
name: Aguinaldo, Alicia M.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Coronaridine (1) was isolated from the CH2Cl2 root extract of Tabernaemontana ternifolia. The structure of 1 was established from 1D- and 2D-NMR and HR-ESIMS experiments, and by comparison with reported spectroscopic data. To date, this is the first report of compound 1 from T. ternifolia, introduced as new Tabernaemontana species from Philippines in 2005 on the basis of morphological characters. Coronaridine, an iboga-type indole alkaloid, has been isolated from over 50 Tabernaemontana species and can thus be inferred as a chemotaxonomic marker of the genus. T. ternifolia has a distinct arrangement of leaves not known in the genus, but is variable in other genera. Its isolation from endemic T. ternifolia establishes its position in the genus and supports the claim that coronaridine is a chemical marker of the genus Tabernaemontana. Interestingly, coronaridine exhibited relatively weak activity against Mycobacterium tuberculosis H37Rv (MIC 82.64 μg/mL) (Rifampicin MIC 0.05 μg/mL).
title: ADCO, Ordre cistercien : comptes (1403-1423) (11 H 1161), f. 00157
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: comptes

description: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161), f. 00157, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
Hierarchy of Relaxation times and Residual Entropy: A Nonequilibrium Approach
Creators: name: Gujrati, P. D.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We consider nonequilibrium (NEQ) states such as supercooled liquids and glasses that are described with use of internal variables. We classify the latter by state-dependent hierarchy of relaxation times to assess their relevance for irreversible contributions. Given an observation time τ_{obs}, we determine the window of relaxation times that divide the internal variables into active and inactive groups, the former playing a central role in the NEQ thermodynamics. Using this thermodynamics, we determine (i) a bound on the NEQ entropy and on the residual entropy, and (ii) the nature of isothermal relaxation of the entropy and the enthalpy in accordance with the second law. A theory that violates the second law such as the entropy loss view is shown to be internally inconsistent if we require it to be consistent with experiments. The inactive internal variables still play an indirect role in determining the temperature T(t), the pressure P(t), of the system, which deviate from their external values.
description: 19 pages, 3 figures
Uncovering a Novel Regulation of Human Epidermal Growth Factor Receptor Signalling by Junctional Adhesion Molecule-A in Breast Cancer
Creators: name: Cruz, Rodrigo
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Junctional Adhesion Molecule-A (JAM-A) is a transmembrane protein with important physiological functions in regulating cell-cell adhesion, and an emerging role in the pathophysiology of breast cancer. JAM-A levels have been reported to regulate expression of the important oncogene Human Epidermal Growth Factor Receptor-2 (HER2) in breast cancer cells, thus we aimed to investigate the underlying mechanisms and whether they extended to regulating the expression of other HER family members. This thesis presents novel evidence that JAM-A expression positively regulates that of HER2 and HER3 at a transcriptional level, accordingly influencing signalling through its downstream effectors and functional outcomes including cell viability, migration and colony formation in vitro and proliferation in a semi-in vivo xenograft model. Mechanistically, the transcription factors ZONAB and FOXA1 were identified as potential regulators of HER expression downstream of JAM-A expression. Overexpression and silencing strategies revealed FOXA1 rather than ZONAB as a key regulator of HER2/3 expression in the breast cancer setting. Specifically, JAM-A expression levels influenced those of FOXA1 at a transcriptional level, and FOXA1 gene silencing reduced both HER2 and HER3 expression. Furthermore, FOXA1 bound specifically to oligonucleotides representing its predicted binding sites in the HER2 and HER3 gene promoters, and JAM-A gene silencing reduced FOXA1 binding to these oligonucleotides. The mechanism whereby JAM-A expression regulates that of FOXA1 appears to involve β-catenin activation and its transit to the nucleus of breast cancer cells, and to be dependent on the dimerization and PDZ-binding domains of JAM-A. Accordingly, a 16 proprietary dimerization-blocking anti-JAM-A peptide reduced cell proliferation and AKT/ERK activation in breast cancer cells. Finally, a stepwise connection between the expression of JAM-A, β-catenin, FOXA1 and HER3 was confirmed by immunohistochemical staining in a tissue microarray derived from invasive breast cancer patient tumours. Taken together, our data provide novel evidence of a direct relationship between levels of JAM-A, β-catenin, FOXA1 and HER2/HER3 in breast cancer cells. In conclusion, we suggest that JAM-A merits investigation as a novel target to inhibit HER2/HER3-dependent tumourigenic signalling in breast cancer.
Water affinity to epitaxial graphene: the impact of layer thickness
Creators: name: Giusca, Cristina E.
name: Panchal, Vishal
name: Munz, Martin
name: Wheeler, Virginia D.
name: Nyakiti, Luke O.
name: Myers-Ward, Rachael L.
name: Gaskill, D. Kurt
name: Kazakova, Olga
Publisher: name: arXiv
Year: 2018
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The sensitivity to water of epitaxial graphene is examined in this study.
Testing the Peculiar Velocity Field predicted from Redshift Surveys
Creators: name: Freudling, Wolfram
name: da Costa, Luiz Nicolaci
name: Pellegrini, Paulo S.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The reconstruction of the peculiar velocity field from the 1.936~Jy iras selected sample of galaxies is compared to a similar reconstruction from an optically selected sample. A general method for combining different samples to reconstruct a self-consistent density and peculiar velocity field is presented. The method is applied to determine how sensitive the derived peculiar velocity field is to the characteristics of the sample used. The possibility that the iras galaxies do not trace the general galaxy population is explored adopting a simple model of linear biasing between the iras and optical samples. We find that the velocity fields derived from the two samples are consistent, within the estimated shot noise error, for the case of no relative bias. This result suggests that the predicted peculiar velocity field based on iras samples is not sensitive to the sampling properties of iras galaxies. Combined with previous suggestion of a relative biasing of iras galaxies on small scales (about 5 h^-1Mpc), this result suggests scale dependent biasing.
description: tar-compressed and uudecoded postscript files, 12 pages+8 figures
Neutrino masses and mixings in a predictive theory of fermion masses
Creators: name: Dimopoulos, S.
name: Hall, L. J.
name: Raby, S.
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A framework for predicting charged fermion masses in supersymmetric grand unified theories is extended to make predictions in the neutrino sector. Eight new predictions are made, and their relevance to neutrino oscillation experiments and the solar neutrino problem are discussed.
description: 13 pages(3 figures not included)
Additional file 5: of Estrogen promotes estrogen receptor negative BRCA1-deficient tumor initiation and progression
Creators: name: Chuying Wang
name: Bai, Feng
name: Zhang, Li-Han
name: Scott, Alexandria
name: Enxiao Li
name: Pei, Xin-Hai
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Plant Biology

description: Figure S5. IHC analysis of ERa and EMT markers for tumors with or without E2 treatment. (A-C) Representative p18-/-;Brca1MGKO and p18-/- mammary tumors treated with E2 or placebo were immunostained with the antibodies indicated. Note the negative ERa staining in E2-treated p18-/-;Brca1MGKO tumors (B) and positive ERa staining in E2-treated p18-/- tumors (C).
title: ADCO, Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0319
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0319, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0319, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Saint-Seine
description: Provenance: http://www.wikidata.org/entity/Q2820709
Additional file 9: of Molecular diversity and function of jasmintides from Jasminum sambac
Creators: name: Kumari, Geeta
name: Wong, Ka
name: Serra, Aida
name: Shin, Joon
name: Yoon, Ho
name: Siu Sze
name: Tam, James
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Table S3. TM align score between jasmintide jS3 and other CRPs with 6 cysteine residues. (DOCX 12 kb)
Heavy Hadron Chiral Perturbation Theory
Creators: name: Cho, Peter
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The formalism and applications of chiral perturbation theory for hadrons containing a single heavy quark are discussed. We emphasize the utility of working directly with the velocity dependent ``super'' fields which appear in the chiral Lagrangian and whose interactions manifestly preserve heavy quark spin symmetry rather than their individual spin components. Chiral logarithm corrections to meson and baryon Isgur-Wise functions are found using these fields. We also identify a unique dimension-five operator which couples the axial vector Goldstone current to the heavy antitriplet baryon field $T_\Q$. We then compute the differential rate for the spin symmetry violating decay $T_b(v) \to T_c(v') \ell \bar{\v}_\ell π$. The ratio of this decay rate to that for the corresponding pure semileptonic transition can be studied away from the zero recoil point.
description: (19 pages, 4 figures available upon request, users Harvmac.tex), HUTP-92/A039
Experimental study of nonclassical teleportation beyond average fidelity
Creators: name: Carvacho, Gonzalo
name: Andreoli, Francesco
name: Santodonato, Luca
name: Bentivegna, Marco
name: D'Ambrosio, Vincenzo
name: Skrzypczyk, Paul
name: Šupić, Ivan
name: Cavalcanti, Daniel
name: Sciarrino, Fabio
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum teleportation establishes a correspondence between an entangled state shared by two separate par- ties that can communicate classically and the presence of a quantum channel connecting the two parties. The standard benchmark for quantum teleportation, based on the average fidelity between the input and output states, indicates that some entangled states do not lead to channels which can be certified to be quantum. It was re- cently shown that if one considers a finer-tuned witness, then all entangled states can be certified to produce a non-classical teleportation channel. Here we experimentally demonstrate a complete characterization of a new family of such witnesses, of the type proposed in Phys. Rev. Lett. 119, 110501 (2017) under different con- ditions of noise. Furthermore, we show non-classical teleportation using quantum states that can not achieve average teleportation fidelity above the classical limit. Our results have fundamental implications in quantum information protocols and may also lead to new applications and quality certification of quantum technologies.
description: 5 pages + Supp. Materials
Prevalence of Psychiatric Morbidity and Behavioural Problems in 22q11.2DS: An Irish Population Study
Creators: name: Prasad, Sarah E.
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Introduction: This population study examines the prevalence of psychiatric morbidity, behavioural difficulties, autistic and schizotypal features in a sample of individuals with 22q11.2DS and in their sibling controls. Methods: Forty-five individuals with 22q11.2DS and their 27 siblings were recruited and studied. Psychiatric morbidity was assessed by using the parent Diagnostic Interview Schedule for Children (DISC-P), Kiddie SADS-Present and Lifetime Version (K-SADPL) (psychotic supplement), Comprehensive Assessment of the At Risk Mental State (CAARMS), Schedule for Clinical Assessment in Neuropsychiatry (SCAN) and the parent Conners' rating scale. Behavioural difficulties were measured by the Strengths and Difficulties Questionnaire (SDQ) and the Child Behaviour Checklist (CBCL). The Social Responsiveness Scale (SRS) and the Social Communication Questionnaire (SCQ) were used to measure symptoms of autism. The Schizotypal Personality Questionnaire (SPQ) was used to measure for schizotypal features. Results: Children and adolescents with 22q11.2DS were found to have more internalising and externalising behaviour compared to their siblings; 25% of children and adolescents with 22q11.2DS had social problems within the clinical range. Individuals with (see Figure 1,2,3,4,5 & 6)
A Six Year Follow-up of the Cavan/Monaghan First Episode Psychosis Study
Creators: name: Kingston, Tara
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Aspects of outcome in first episode psychosis require clarification. In doing so, boundaries between diagnoses within the psychosis spectrum of disorders may be better understood, thus contributing to improvement in operational diagnoses of psychotic disorders. In addition, the place within the spectrum of psychotic disorders of lesser studied diagnoses, such as major depressive disorder with psychotic features, is unclear. This study is a six year follow-up of the CavanMonaghan First Episode Psychosis Study, and investigates outcomes in a cohort characterised by substantive ethnic and socioeconomic homogeneity and stability. This study examines key aspects and predictors of outcome, including diagnostic stability, psychopathology, social and occupational functioning, quality of life and service-engagement. Three major diagnostic nodes, schizophrenia, bipolar disorder and major depressive disorder with psychotic features emerge from the data. Schizoaffective disorder appears to inhabit the territory between these three nodes. Schizophreniform disorder appears primarily a progenitor of schizophrenia, while delusional disorder appears primarily a variant progenitor of schizophrenia and schizoaffective disorder. Brief psychotic disorder appears to be related prospectively to bipolar disorder and major depressive disorder, while substance-induced psychosis and psychosis not otherwise specified appear to be related prospectively to schizophrenia and schizoaffective disorder. Follow-up data on psychopathology, functioning, QOL and service engagement result in an overall picture of SZ having the most adverse outcome of all the diagnoses within the psychotic spectrum. Systematic comparisons are made with SA, BD and MDDP. Additionally, the study illuminates rarely considered aspects of SF, DD, BrPsy, PNOS, SIP, SIM, PGMC and MGMC. Extent of psychopathology has a notably adverse effect on outcome for all diagnoses, whereas an ability to maintain social integration and a more 'normal' life course appears to have a positive effect on outcome. These fmdings have implications for the approach to treatment across psychotic disorders: broader symptom management, whether via pharmacological or psychotherapeutic approaches, may prevent particularly adverse outcomes, and interventions that promote occupational and social integration are key in raising outcomes beyond the level achievable by symptom management alone.
Thickness dependent hydrophobicity of epitaxial graphene
Creators: name: Munz, M.
name: Giusca, C. E.
name: Myers-Ward, R. L.
name: Gaskill, D. K.
name: Kazakova, O.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: This article addresses the much debated question whether the degree of hydrophobicity of single-layer graphene (1LG) is different from the one of double-layer graphene (2LG). Knowledge of the water affinity of graphene and its spatial variations is critically important as it can affect the graphene properties as well as the performance of graphene devices exposed to humidity. By employing chemical force microscopy (CFM) with a probe rendered hydrophobic by functionalization with octadecyltrichlorosilane (OTS), the adhesion force between the probe and epitaxial graphene on SiC has been measured in deionized water. Owing to the hydrophobic attraction, a larger adhesion force was measured on 2LG domains of graphene surfaces, thus showing that 2LG is more hydrophobic than 1LG. Identification of 1LG and 2LG domains was achieved through Kelvin probe force microscopy and Raman spectral mapping. Approximate values of the adhesion force per OTS molecule have been calculated through contact area analysis. Furthermore, the contrast of friction force images measured in contact mode was reversed to the 1LG/2LG adhesion contrast and its origin was discussed in terms of the likely water depletion over hydrophobic domains as well as deformation in the contact area between AFM tip and 1LG.
description: This document is the unedited Author's version of a Submitted Work that was subsequently accepted for publication in ACS Nano \copyright American Chemical Society after peer review. To access the final edited and published work see URL: https://pubs.acs.org/doi/abs/10.1021/acsnano.5b03220
A Survey of Faint Galaxy Pairs
Creators: name: Carlberg
name: Pritchet
name: Infante
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A sample of faint, V magnitude selected, galaxy pairs, having physical separations less than approximately 20\hkpc, is used to examine the rise in the merger rate with redshift and the statistical relations between close pairs and the field galaxy population. Redshifts have been obtained for 14 galaxies ($V \le 22.5$) that are in close ($θ< 6\arcs$) pairs, along with a comparison sample of 38 field galaxies. Two color photometry is available for about 1000 galaxies in the same fields. The average redshift of the $V\le22.5$ field population is 0.36, statistically equal to the average redshift of 0.42 for the pairs. The similarity of the two redshift distributions, $Δz\le 0.1$, limits any differential luminosity enhancement of close pairs to less than half a magnitude. The pairs are somewhat bluer than the field and have nearly twice the average [O~II] detection rate of the field, but the differences are not statistically significant. The field population has an angular correlation at separations of $θ\le$6\arcs\ higher than the inward extrapolation of $ω(θ)\propto θ^{-0.8}$, which may be a population of ``companions'' not present at the current epoch, or, luminosity enhancement of intrinsically faint galaxies in pairs. Physical pairs comprise about 7\% of the faint galaxies in our survey fields. The same physical separation applied to local galaxies finds only 2.6\% in pairs. If the rise in close low relatively velocity pairs with redshift is parameterized as $(1+z)^m$, then $m=2.9\pm0.8$. If all pairs at low velocities and $r\le 20$\hkpc\ merge, then the
description: 16p plain tex, uuencoded compressesd postscript available via anonymous ftp from moonray.astro.utoronto.ca in pub/pairs.ps.Z.uu Problems and queries to carlberg@hermes.astro.washington.edu
title: ADCO, Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0197
Creators: name: de la Côte d'Or, Archives départementales
name: CG21/F.PETOT/2009
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0197, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0197, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Saint-Seine
description: Provenance: http://www.wikidata.org/entity/Q2820709
Additional file 9: of ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis
Creators: name: Dumortier, Mandy
name: Ladam, Franck
name: Damour, Isabelle
name: Vacher, Sophie
name: Bièche, Ivan
name: Marchand, Nathalie
name: Launoit, Yvan De
name: Tulasne, David
name: Chotteau-Lelièvre, Anne
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: Figure S7. High MMP13 mRNA expression level is associated with a poor prognosis in breast cancer. a Metastasis-free survival (MFS) curves for patients with breast tumors according to Low-MMP13 (n = 321) or High-MMP13 (n = 135) mRNA levels. ***P ≤ 0.001. b Metastasis-free survival (MFS) curves for patients with breast tumors according to Low-ETV4 (n = 82) and High-ETV4 (n = 374) mRNA levels. The results were not statistically significant. (PDF 14 kb)
Additional file 7: of Consistent and reproducible long-term in vitro growth of health and disease-associated oral subgingival biofilms
Creators: name: Velsko, Irina
name: Shaddox, Luciana
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Figure S5. Principal coordinates analysis of jack-knifed beta diversity by weighted UniFrac and Sorensen distances of biofilms. Biofilms cluster based on disease status of original plaque inocula and disease site-derived biofilms separate based on donor. (a) Biofilm coordinates exhibit very little variation in PCoA based on weighted UniFrac distance. (b) Biofilm coordinates demonstrate variation in PCoA based on Sorensen distance but retain distinct clustering of healthy and disease site-derived groups. Additionally, disease site-derived biofilms likewise retain distinct separation into groups based on plaque inocula donor. (PDF 1518 kb)
Spin transport in graphene/transition metal dichalcogenide heterostructures
Creators: name: Garcia, Jose H.
name: Vila, Marc
name: Cummings, Aron W.
name: Roche, Stephan
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Since its discovery, graphene has been a promising material for spintronics: its low spin-orbit coupling, negligible hyperfine interaction, and high electron mobility are obvious advantages for transporting spin information over long distances. However, such outstanding transport properties also limit the capability to engineer active spintronics, where strong spin-orbit coupling is crucial for creating and manipulating spin currents. To this end, transition metal dichalcogenides, which have larger spin-orbit coupling and good interface matching, appear to be highly complementary materials for enhancing the spin-dependent features of graphene while maintaining its superior charge transport properties. In this review, we present the theoretical framework and the experiments performed to detect and characterize the spin-orbit coupling and spin currents in graphene/transition metal dichalcogenide heterostructures. Specifically, we will concentrate on recent measurements of Hanle precession, weak antilocalization and the spin Hall effect, and provide a comprehensive theoretical description of the interconnection between these phenomena.
description: 21 pages, 11 figures. This document is the unedited Author's version of a Submitted Work that was subsequently accepted for publication in Nano Letters, copyright\c{opyright}American Chemical Society after peer review. To access the final edited and published work see http://pubs.rsc.org/en/Content/ArticleLanding/2018/CS/C7CS00864C
The role of parathyroid hormone in bone healing.
Creators: name: Padhraig F. O'Loughlin
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Animal fracture models have been extensively applied to pre-clinical research as a platform to identify and characterize normal and abnormal physiological processes and develop specific maneuvers that alter the biology and biomechanics being examined. The choice of animal model employed in a study bears a direct relationship to the specific intervention being analyzed. The animal models employed should be described clearly, control group data should be established and reproducibility should be defined from experiment to experiment and from institution to institution so that quantitative and qualitative outcomes can be reliably compared and contrasted to other related studies.
The Inflationary Energy Scale
Creators: name: Liddle, Andrew R
Publisher: name: arXiv
Year: 1993
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The energy scale of inflation is of much interest, as it suggests the scale of grand unified physics and also governs whether cosmological events such as topological defect formation can occur after inflation. The COBE results are used to limit the energy scale of inflation at around 60 $e$-foldings from the end of inflation. An exact dynamical treatment based on the Hamilton-Jacobi equations is then used to translate this into limits on the energy scale at the end of inflation. General constraints are given, and then tighter constraints based on physically motivated assumptions regarding the allowed forms of density perturbation and gravitational wave spectra. These are also compared with the values of familiar models.
description: 17 pages (plus three figures, available from the author as hard copies only), standard LaTeX, SUSSEX-AST 93/7-2
Detuning the Honeycomb of $α$-RuCl$_{3}$: Pressure-Dependent Optical Studies Reveal Broken Symmetry
Creators: name: Biesner, Tobias
name: Biswas, Sananda
name: Li, Weiwu
name: Saito, Yohei
name: Pustogow, Andrej
name: Altmeyer, Michaela
name: Wolter, Anja U. B.
name: Büchner, Bernd
name: Roslova, Maria
name: Doert, Thomas
name: Winter, Stephen M.
name: Valentí, Roser
name: Dressel, Martin
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The honeycomb Mott insulator $α$-RuCl$_3$ loses its low-temperature magnetic order by pressure. We report clear evidence for a dimerized structure at $P>1$ GPa and observe the breakdown of the relativistic $j_{\rm eff}$ picture in this regime strongly affecting the electronic properties. A pressure-induced Kitaev quantum spin liquid cannot occur in this broken symmetry state. We shed light on the new phase by broad-band infrared spectroscopy of the low-temperature properties of $α$-RuCl$_{3}$ and ab initio density functional theory calculations, both under hydrostatic pressure.
description: 5 pages, 4 figures
title: 01_1957
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Additional file 4: of Estrogen promotes estrogen receptor negative BRCA1-deficient tumor initiation and progression
Creators: name: Chuying Wang
name: Bai, Feng
name: Zhang, Li-Han
name: Scott, Alexandria
name: Enxiao Li
name: Pei, Xin-Hai
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Figure S4. Estrogen promotes lung metastasis of Brca1-deficient mammary tumors. (A, B) Metastatic p18-/-;Brca1MGKO tumor cells were inoculated into the MFPs of NSG mice with either E2 or placebo supplement. When newly generated tumors reached maximum size allowed by the IACUC in 3â 6Â weeks, or the mice became moribund, lungs were dissected for analysis. Representative gross pictures (A) and H.E. staining (B) of lungs are shown.
Metastable Cosmic Strings in Realistic Models
Creators: name: Holman, R.
name: Hsu, S. D. H.
name: Vachaspati, T.
name: Watkins, R.
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the stability of the electroweak Z-string at high temperatures. Our results show that while finite temperature corrections can improve the stability of the Z-string, their effect is not strong enough to stabilize the Z-string in the standard electroweak model. Consequently, the Z-string will be unstable even under the conditions present during the electroweak phase transition. We then consider phenomenologically viable models based on the gauge group $SU(2)_L \times SU(2)_R \times U(1)_{B-L}$ and show that metastable strings exist and are stable to small perturbations for a large region of the parameter space for these models. We also show that these strings are superconducting with bosonic charge carriers. The string superconductivity may be able to stabilize segments and loops against dynamical contraction. Possible implications of these strings for cosmology are discussed.
description: 24 pages, 2 figures (available on request); HUTP-92/A032, Fermilab-Pub-92/228-A
Few-body quark dynamics for doubly-heavy baryons and tetraquarks
Creators: name: Richard, Jean-Marc
name: Valcarce, Alfredo
name: Vijande, Javier
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We discuss the adequate treatment of the 3- and 4-body dynamics for the quark model picture of double-charm baryons and tetraquarks. We stress that the variational and Born-Oppenheimer approximations give energies very close to the exact ones, while the diquark approximation might be rather misleading. The Hall-Post inequalities also provide very useful lower bounds that exclude the possibility of stable tetraquarks for some mass ratios and some color wave functions.
description: 10 pages, 9 figures, to appear in Phys. Rev. C, one ref. added
A novel study on the functional relevance of junctional adhesion molecule -A in breast cancer.
Creators: name: Gozie Offiah
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Breast cancer, a disease that arises from the epithelial cells within breast tissue, is a common illness that can affect all age groups. Each year it is diagnosed in an estimated 1 million women worldwide, and accounts for over 450,000 deaths. Despite advancements in breast cancer screening and treatment, breast cancer still remains one of the leading causes of female deaths worldwide. Breast cancer is a heterogeneous disease encompassing many subtypes, which differ both in terms of their molecular backgrounds and clinical prognosis. Cancer initiation and progression is a multistep process involving dysregulations in cell adhesion, proliferation, survival and migration. Breast epithelial cells contain several multi-protein adhesion complexes at two principal sites, between neighbouring cells and between cells and their extracellular matrix. Adhesion proteins regulate a variety of cellular functions, and dysregulation of cellular adhesion has been implicated in the events that accompany cancer initiation and progression. Proteins of the intercellular tight junction have been found to be de-regulated in several human cancers including breast, and have recently been suggested as promising targets for cancer therapy. This thesis is focused on exploring the contribution of one tight junction protein, junctional adhesion molecule-A (JAM-A) to breast cancer progression. In this thesis we used two isogenic breast cancer cell line models, HMT-3522 and Hs578T, both of which have "non-tumorigenic" and "tumorigenic" variants. We observed that tumorigenic HMT- 3522 T4-2 cells had tighter junctions compared to non- tumorigenic cells, and that the tumorigenic variant of Hs578T cells expressed a higher level of JAM-A. JAM-A expression was also higher in primary breast cultures from tumour relative to non-tumour samples, and highest in aggressive high grade turnours. Interestingly, we detected high levels of soluble JAM-A in serum samples of breast cancer patients with benign disease compared to patients with invasive ductal carcinomas. Functional inhibition of JAM-A was found to decrease protein levels of JAM-A in both nontumorigenic and tumorigenic cells and to significantly reduce ceII migration. In 3-dimensional cultures mimicking the in vivo microenvironment, JAM-A inhibition was found to decrease cell number and 3-dimensional spheroid formation and, for the first time, to partially normalise the ahomalltumorigenic phenotype of invasive cells. Taken together, our study provides novel evidence suggesting that JAM-A may be involved in breast cancer progression and have potential as a biomarker of disease progression or as a therapeutic target.
A Recipe for Galaxy Formation Shaun Cole
Creators: name: Aragon-Salamanca, Alfonso
name: Frenk, Carlos S.
name: Navarro, Julio F.
name: Zepf, Stephen E.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a detailed prescription for how galaxy formation can be modelled in hierarchical theories of structure formation. Our model incorporates the formation and merging of dark matter halos, the shock heating and radiative cooling of baryonic gas gravitationally confined in these halos, the formation of stars regulated by the energy released by evolving stars and supernovae, the merging of galaxies within dark matter halos, and the spectral evolution of the stellar populations that are formed. The procedure that we describe is very flexible and can be applied to any hierarchical clustering theory. We explore the effects of varying the stellar initial mass function, star formation rates and galaxy merging. The results we compare with an extensive range of observational data, including the B and K galaxy luminosity functions, galaxy colours, the Tully-Fisher relation and galaxy number counts.These data strongly constrain the models and enable the relative importance of each of the physical process to be assessed. We present a broadly successful model defined by a plausible choice of parameters. This fiducial model produces a much more acceptable luminosity function than most previous studies. This is achieved through a modest rate of galaxy mergers and strong suppression of star formation in halos of low circular velocity. However, it fails to produce galaxies as red as many observed ellipticals and, compared with the observed Tully-Fisher relation, the model galaxies have circular velocities which are too large. ** uuencoded compressed postscript file containing all text and figures.**
Gravitational Instability of Cold Matter
Creators: name: Bertschinger, Edmund
name: Jain, Bhuvnesh
Publisher: name: arXiv
Year: 1993
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We solve the nonlinear evolution of pressureless, irrotational density fluctuations in a perturbed Robertson-Walker spacetime using a new Lagrangian method based on the velocity gradient and gravity gradient tensors. Borrowing results from general relativity, we obtain a set of Newtonian ordinary differential equations for these quantities following a given mass element. Using these Lagrangian fluid equations we prove the following results: (1) The spherical tophat perturbation, having zero shear, is the slowest configuration to collapse for a given initial density and growth rate. (2) Initial density maxima are not generally the sites where collapse first occurs. (3) Initially underdense regions may undergo collapse if the shear is not too small. If the magnetic part of the Weyl tensor vanishes, the nonlinear evolution is described purely locally by our equations; this condition holds for spherical, cylindrical, and planar perturbations and may be a good approximation in other circumstances. Assuming the vanishing of the magnetic part of the Weyl tensor, we compute the exact nonlinear gravitational evolution of cold matter. We find that 56\% of initially underdense regions collapse in an Einstein-de Sitter universe for a homogeneous and isotropic random field. We also show that, given this assumption, the final stage of collapse is generically two-dimensional, leading to strongly prolate filaments rather than Zel'dovich pancakes. While this result may explain the prevalence of filamentary collapses in N-body simulations, it is not true in general, suggesting that the magnetic part of the Weyl tensor need not vanish in the Newtonian limit.
description: 23 pages, AAS LaTeX 3.0, postscript with figures available by anonymous ftp to arcturus.mit.edu, revised version of MIT CSR-93-14; ApJ, in press
Hydrogen Clouds and the MACHO/EROS Events
Creators: name: Henriksen, Richard N.
name: Widrow, Lawrence M.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We propose that the recently reported MACHO/EROS events correspond to gravitational amplification by dark clouds rather than compact objects. These clouds must be very dense with $M\sim 0.1 ~M_\odot$ and $R\la 10^{14}~{\rm cm}$. In all likelihood, the clouds will be members of a family of objects with different sizes and masses. We therefore expect events of longer duration than the ones reported by the MACHO and EROS groups but with light curves very different from the ones derived assuming point mass lenses. We suggest that one such event has already been observed in radio measurements of the quasar 1502+106. The abundances of free electrons, metals, complex molecules, and dust grains are constrained to be very small suggesting that the clouds are formed from a primordial mixture of hydrogen and helium. Cosmic rays and background UV radiation ionize a halo around the cloud. Radio waves from distant sources will be scattered by the electrons in this halo, an effect which may have already been observed in quasars such as 1502+106. We argue that dark clouds are a viable alternative to compact objects for baryonic dark matter in the halo.
description: 11 pages, LaTex
Manufacturing processes hardware and software development to implement innovative technologies of aircraft manufacturing facilities management
Creators: name: Pyatovsky, S. E.
name: Serdyuchenko, A. N.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: The paper presents approaches to modern aircraft manufacturing facilities' competitiveness growth based on innovative technologies of management decisions implementation. The paper establishes a connection between the aircraft industry and the development of the national economy, along with the dependence of the Russian economy on international manufacturers of civil airplanes. Comparative statistics of civil aircrafts produced by Russian and international manufacturers are given. Comparative analysis of military and civil aviation is done. It is shown that project implementation based on Open Source and OLAP-technologies at a high-technology enterprise is a pre-requisite for the competitive growth of aircraft manufacturing facilities.