cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identification of the Polycomb protein CBX2 as a potential drug target in advanced prostate cancer and beyond
Creators: name: Clermont, Pier-Luc
Publisher: name: University of British Columbia
Year: 2015

description: Globally, prostate cancer (PCa) represents the most commonly diagnosed cancer in men. While localized PCa can often be cured, all patients with metastatic disease inevitably develop castration-resistant prostate cancer (CRPC) or neuroendocrine prostate cancer (NEPC). Increasing evidence suggests that epigenetic alterations involving the Polycomb Group (PcG) family drive PCa progression. Although the PcG protein CBX2 is required for prostate development, its implication in human cancer remains unexplored. I therefore hypothesized that CBX2 may become deregulated during PCa progression and induce transcriptional programs promoting PCa aggressiveness. Using patient-derived xenografts and clinical datasets, I have explored the epigenetic landscape of advanced PCa and identified the Polycomb Group protein and epigenetic reader CBX2 as a potential drug target. First, CBX2 was significantly up-regulated in metastatic and castration-resistant PCa tissues. Furthermore, CBX2 overexpression predicted lower overall survival and correlated with numerous adverse prognostic factors. In addition, CBX2 depletion induced proliferation arrest and apoptosis in metastatic PCa cell lines, implying that CBX2 is required for PCa cell survival. Microarray analysis conducted after CBX2 silencing revealed that CBX2 regulates many genes controlling cellular proliferation and differentiation. Given the rising incidence of NEPC in advanced PCa, I analyzed whether CBX2 was also involved in NEPC pathogenesis. Strikingly, CBX2 was consistently the most highly up-regulated epigenetic regulator across multiple clinical and xenograft tumor tissues. Furthermore, I derived a list of 185 genes down-regulated in NEPC that was preferentially enriched in PcG target genes and predicted poor clinical outcome, in line with a critical function for CBX2 in late-stage PCa. Since CBX2 has never been linked to human cancers, I conducted a comprehensive meta-analysis of CBX2 across many tumor types using previously published clinical data. Strikingly, these studies demonstrated that the CBX2 locus is rarely inactivated or down-regulated. In contrast, CBX2 was frequently amplified and over-expressed in many common tumors, where it correlated with metastatic dissemination and poor clinical outcome. Overall, this work identifies CBX2 as novel epigenetic driver of cancer progression and investigates the therapeutic potential of CBX2 in advanced solid malignancies.
Mentorship programs and the novice nurse : a rapid evidence assessment
Creators: name: Erickson, Stephanie Kyla
Publisher: name: University of British Columbia
Year: 2015

description: New graduate registered nurses (RNs) experience many challenges as they transition from the role of student nurse to professional nurse. Mentoring can support new nurses with the development of clinical nursing skills and competencies, and is linked to professionalism, nursing quality improvement, self-confidence, retention, and job satisfaction. This rapid evidence assessment (REA) addresses how new graduate mentorship programs can be effective in improving performance, satisfaction, retention, and confidence in novice nurses’ practice. It also reports the key elements of effective new graduate mentorship programs and reported problems in implementing new graduate RN mentorship programs. Seventeen research studies were selected for inclusion and examined using Bandura’s social learning theory. The data from each research study was extracted using the EPPI-Centre Data Extraction and Coding Tool for Education Studies to allow for mapping and analysis. Each research study was then scored from highest level of evidence to lowest level of evidence. The findings were then synthesized to suggest that mentorship programs can be effective in improving performance, satisfaction, retention, and confidence in novice nurses’ practice under the right conditions. The reported key elements of effective new graduate RN mentorship programs include mentor-mentee matching, availability of mentors, adequate training and preparation of mentors, commitment and support, and length of the mentoring relationship. The reported problems in implementing new graduate RN mentorship programs include lack of training and preparation of mentors and mentees, availability of mentors, and mentor-mentee mismatch.
Effect of non-thermal plasma on the bond strength of orthodontic brackets to enamel : an invitro study
Creators: name: Arora, Deepak
Publisher: name: University of British Columbia
Year: 2015

description: Objectives: Non-thermal plasma (NTP) has been used to modify enamel and dentin surfaces and improve the interfacial bonding of dental composite restorations. NTP is shown to cause super hydrophilic surface by decreasing the contact angle measurements and improve the quality of the adhesive - enamel and adhesive - dentin interface. We sought to determine the effects of NTP treatment on the bond strength of brackets to enamel. We investigated the application of NTP alone and in combination with phosphoric acid (PA) etching and assessed the outcomes after 24 hours and 1 month. Methods: 84 extracted pre-molars washed and disinfected were divided into 2 broad groups: No-treatment and Treatment group. No - treatment group consisted of 12 premolars on which orthodontic bracket bonding was performed without any surface - treatment except for polishing with pumice. Treatment group consisted of 72 premolars which were divided randomly into 3 main groups of 24 premolars each. These groups were Group 1: PA Etch (30s), Group 2: PA Etch (30s) + NTP (30s) and Group 3 NTP (30s). The bonded teeth were stored in water at 37° C and tested in shear mode after 24 hours and 1 month (n= 12). The fracture mode and adhesive remnant index were determined on de-bonded surfaces. SEM pictures were taken from enamel surfaces after each treatment. Results: During the first 24 hours of testing, SBS was maximum with Etch+ NTP and Etch treated group followed by NTP group ( P < 0.05). After 1 month of ageing the SBS was maximum with the Etch group followed by Etch+ NTP and NTP group ( P < 0.05). ARI scoring was higher with Etch and Etch+ NTP group. SEM pictures showed Type 1 acid etch pattern with Etch and Etch+ NTP group whereas NTP treated group showed no surface changes. Conclusions: NTP application by itself has a potential to bond orthodontic brackets however a longer ageing time will explain more about this feasibility.
Minuscule corrections to near-surface solar internal rotation using mode-coupling
Creators: name: Das, Srijan Bharati
name: Kashyap, Samarth G.
name: Oktay, Deniz
name: Hanasoge, Shravan M.
name: Tromp, Jeroen
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The observed solar oscillation spectrum is influenced by internal perturbations such as flows and structural asphericities. These features induce splitting of characteristic frequencies and distort the resonant-mode eigenfunctions. Global axisymmertric flow -- differential rotation -- is a very prominent perturbation. Tightly constrained rotation profiles as a function of latitude and radius are products of established helioseismic pipelines that use observed Dopplergrams to generate frequency-splitting measurements at high precision. However, the inference of rotation using frequency-splittings do not consider the effect of mode-coupling. This approximation worsens for high-angular-degree modes, as they become increasingly proximal in frequency. Since modes with high angular degrees probe the near-surface layers of the Sun, inversions considering coupled modes could potentially lead to more accurate estimates of rotation very close to the surface. In order to investigate if this is indeed the case, we perform inversions for solar differential rotation, considering coupling of modes for angular degrees $160 \leq \ell \leq 300$ in the surface gravity $f$-branch and first-overtone $p$ modes. In keeping with the character of mode coupling, we carry out a non-linear inversion using an eigenvalue solver. Differences in inverted profiles for frequency splitting measurements from MDI and HMI are compared and discussed. We find that corrections to the near-surface differential rotation profile, when accounting for mode-coupling effects, are smaller than 0.003 nHz and hence are insignificant. These minuscule corrections are found to be correlated with the solar cycle. We also present corrections to even-order splitting coefficients, which could consequently impact inversions for structure and magnetic fields.
description: 21 pages; 15 figures; Accepted for publication in the Astrophysical Journal Supplement Series
Additional file 5 of Predicting the nature of pleural effusion in patients with lung adenocarcinoma based on 18F-FDG PET/CT
Creators: name: Li, Yi
name: Mu, Wei
name: Li, Yuan
name: Song, Xiao
name: Huang, Yan
name: Jiang, Lei
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 5: Table 3. Univariate logistic regression analyses for the diagnosis of MPE in the test cohort.
Antifibrotische Effekte von DBTC-Foxf1 siRNA-Formulierungen im murinen Modell der cholestatischen Leberfibrose
Creators: name: Brensel, Malte Thomas
Publisher: name: Universität Rostock
Year: 2019
Subjects: subject: 570 Life science
subject: 610 Medical sciences Medicine

description: Ein wesentlicher Schritt in der Entstehung der Leberfibrose ist die Aktivierung hepatischer Sternzellen (HSC), wobei hierbei unter anderem eine veränderte Expression von Transkriptionsfaktoren vorliegt. Für den Transkriptionsfaktor forkhead box f1 (Foxf1) ist bekannt, dass dessen verstärkte Expression aktivierend auf HSC wirkt. In dieser Arbeit wurde daher mit dem Konzept der Gen-Interferenz durch small interfering RNA (siRNA) im murinen Modell der cholestatischen Leberfibrose untersucht, ob ein Foxf1-Silencing in den HSC zu antifibrotischen Effekten führt.
Herbig-Haro Flows and Young Stars in the Dobashi 5006 Dark Cloud
Creators: name: Movsessian, T. A.
name: Magakian, T. Yu.
name: Rastorguev, A. S.
name: Andreasyan, H. R.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Two new Herbig-Haro flows were found in a study of the isolated Dobashi 5006 dark cloud (l$= 216^\circ.7$, b= $-$13$^\circ.9$): one certain (HH 1179) and one presumable, associated with the infrared sources 2MASS 06082284$-$0936139 and 2MASS 06081525$-$0933490, correspondingly. Judging from their spectral energy distributions, these sources may be Class 1 objects with luminosities of order 23 $L_{\odot}$ and 3.6 $L_{\odot}$ , respectively. They are part of the poor star cluster MWSC 0739, study of which based on data from the Gaia DR3 survey has made it possible to detect 17 stars which are probably members of it. A list of them and their main parameters is given. The distance of the cluster is estimated to be 820 pc and the color excess on the path to the cluster is E(BP-RP) $\approx$1.05 mag. All of these stars are PMS-objects and most of them are optically variable. It is concluded that the newly discovered compact star-formation zone in the Dobashi 5006 cloud has an age of no more than a few million years and this process continues up to the present time.
On the uniform equidistribution of closed horospheres in hyperbolic manifolds
Creators: name: Södergren, Anders
Publisher: name: arXiv
Year: 2011
Subjects: subject: Dynamical Systems (math.DS)
subject: Spectral Theory (math.SP)
subject: FOS: Mathematics
subject: 37D40, 11F

description: We prove asymptotic equidistribution results for pieces of large closed horospheres in cofinite hyperbolic manifolds of arbitrary dimension. This extends earlier results by Hejhal and Strömbergsson in dimension 2. Our proofs use spectral methods, and lead to precise estimates on the rate of convergence to equidistribution.
description: 58 pages
The Hunger Games fanfiction as a community of practice : forming identities in online communities
Creators: name: Henderson, Susan
Publisher: name: University of British Columbia
Year: 2015

description: This research investigates expressions of identity and formation of identity found in an online fanfiction forum based on the young adult novel, The Hunger Games, by Suzanne Collins. Using Wenger’s neo-Vygotskian socio-cultural learning theorem from his book, Communities of Practice I observed, then coded posts by authors and respondents using a rubric I operationalized from Wenger’s five characteristics of identity in practice. I employed a deductive coding scheme and used Wenger’s community of practice as a framework. During the coding process, I found many examples of what seem to be expressions of identity in practice and what appear to be examples of identity in formation. I discuss how this online fanfiction forum operates as a community of practice and consider how this fanfiction space informs other educational applications. There are different instructional strategies that could be gleaned from the coding and analysis process that practicing teachers and librarians could implement into their current online or offline practices. This fanfiction forum is an example of a self-selected online activity with a high level of reading and writing engagement. There are many exciting signs of educational and developmental activities occurring in this fanfiction forum, which suggests further investigation is needed.
Thermodynamic and Magnetic Topology Evolution of the X1.0 Flare on 2021 October 28 Simulated by a Data-driven Radiative Magnetohydrodynamic Model
Creators: name: Guo, Jin-han
name: Ni, Yi-wei
name: Zhong, Ze
name: Guo, Yang
name: Xia, Chun
name: Li, Hai-tang
name: Poedts, Stefaan
name: Schmieder, Brigitte
name: Chen, Peng-fei
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Solar filament eruptions, flares and coronal mass ejections (CMEs) are manifestations of drastic release of energy in the magnetic field, which are related to many eruptive phenomena from the Earth magnetosphere to black hole accretion disks. With the availability of high-resolution magnetograms on the solar surface, observational data-based modelling is a promising way to quantitatively study the underlying physical mechanisms behind observations. By incorporating thermal conduction and radiation losses in the energy equation, we develop a new data-driven radiative magnetohydrodynamic (MHD) model, which has the capability to capture the thermodynamic evolution compared to our previous zero-\b{eta} model. Our numerical results reproduce major observational characteristics of the X1.0 flare on 2021 October 28 in NOAA active region (AR) 12887, including the morphology of the eruption, kinematic of flare ribbons, extreme-ultraviolet (EUV) radiations, and two components of the EUV waves predicted by the magnetic stretching model, i.e., a fast-mode shock wave and a slower apparent wave due to successive stretching of magnetic field lines. Moreover, some intriguing phenomena are revealed in the simulation. We find that flare ribbons separate initially and ultimately stop at the outer stationary quasi-separatrix layers (QSLs). Such outer QSLs correspond to the border of the filament channel and determine the final positions of flare ribbons, which can be used to predict the size and the lifetime of a flare before it occurs. In addition, the side view of the synthesized EUV and white-light images exhibit typical three-part structures of CMEs, where the bright leading front is roughly cospatial with the non-wave component of the EUV wave, reinforcing the magnetic stretching model for the slow component of EUV waves.
description: 46 pages, 15 figures, accepted for publication in The Astrophysical Journal Supplement
Relative efficiency of three mechanisms of vector fields growth in a random media
Creators: name: Illarionov, E. A.
name: Sokoloff, D. D.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: We consider a model of a random media with fixed and finite memory time with abrupt losses of memory (renovation model). Within the memory intervals we can observe either amplification or oscillation of the vector field in a given particle. The cumulative effect of amplifications in many subsequent intervals leads to amplification of the mean field and mean energy. Similarly, the cumulative effect of intermittent amplifications or oscillations also leads to amplification of the mean field and mean energy, however, at a lower rate. Finally, the random oscillations alone can resonate and yield the growth of the mean field and energy. These are the three mechanisms that we investigate and compute analytically and numerically the growth rates based on the Jacobi equation with the random curvature parameter.
Eco-industrial network planning in the face of climate change : an exploratory study using landscape planning approaches
Creators: name: LaValle, Alicia Veronica
Publisher: name: University of British Columbia
Year: 2015

description: This study explores the opportunities and challenges in combining three areas of planning: Eco-Industrial Networking, Climate Change Adaptation and Climate Change Mitigation. The Tilbury Industrial Park in the Corporation of Delta on the Fraser River was used as a case study to examine opportunities and challenges in integrating eco-industrial network planning into climate change planning, with a focus on adapting to local climate change vulnerabilities. A multi-phase approach was used including document analysis, precedent case studies, indicator development, mapping, industry leader interviews and guided feedback from expert reviewers in the planning sector. The goal was to understand existing knowledge and perceptions in these three areas of planning, and to use visual tools to engage further exploration of ideas that may support more than one planning objective simultaneously. Study findings suggest that industry leaders’ understanding and perceptions of the three areas are inconsistent. Interview participants had the greatest understanding of climate change mitigation goals, though not always positive perceptions of the mitigation policy tools being used. There was some understanding of eco-industrial networks (EIN), with generally positive attitudes towards the concepts in meeting industry planning and sustainability ambitions. Climate change adaptation was least well understood initially but enhanced by visual tools presented to participants, which focused mainly on localized and interactive maps. None of the three areas of planning (adaptation, mitigation, and EIN) appeared to be strong drivers of change, with the exception of mitigation more recently driven especially by corporate policy. Visual tools led to better understanding of EIN and climate change planning and new ideas. This suggests that these methods could be replicated and enhanced within more formal planning processes for further co-development of knowledge and opportunities for integrating EIN and climate change planning, in Delta and beyond. Additionally this could promote positive perceptions of new climate change adaptation plans in the future. Using the methods explored here could lead to co-benefits being better understood by industry stakeholder and may support more integrated planning, building on positive inertia from existing collaborations at Tilbury. Recommendations for government and industry to further these aims are provided.
Programmable entanglement oscillations in a non Markovian channel
Creators: name: Cialdi, Simone
name: Brivio, Davide
name: Tesio, Enrico
name: Paris, Matteo G. A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We suggest and demonstrate an all-optical experimental setup to observe and engineer entanglement oscillations of a pair of polarization qubits in a non-Markovian channel. We generate entangled photon pairs by spontaneous parametric downconversion (SPDC), and then insert a programmable spatial light modulator in order to impose a polarization dependent phase-shift on the spatial domain of the SPDC output and to create an effective non-Markovian environment. Modulation of the enviroment spectrum is obtained by inserting a spatial grating on the signal arm. In our experiment, programmable oscillations of entanglement are achieved, with the maximally revived state that violates Bell's inequality by 17 standard deviations.
description: 4 pages, 4 figures
Expressive microtimings and groove in Scottish Gaelic fiddle music
Creators: name: Glen, Katherine Marshall
Publisher: name: University of British Columbia
Year: 2015

description: This project examines how “groove” can be created through the microtimings of a solo instrument, rather than as discrepancies between multiple instruments or parts, as is often the case in similar studies. Groove is the nuanced rhythmic element of music in which microtiming patterns play upon listeners’ bodies in complex ways and stimulate movement. My study focuses on the reel, a type of dance tune used in the Scottish Gaelic tradition. Despite the repetitiveness and relative simplicity of the melody in this genre, these tunes have been widely played and performed for many years, and this seems to be due, in large part, to their rhythmic features. I analyze five recordings of a popular reel, “Jenny Dang the Weaver,” by different performers, using methodologies typically applied to the jazz canon. Each recording features only a solo fiddle, so any expressive microtimings are the result of the single performer and musical line, not influenced by interaction with other instruments. My analysis demonstrates that these recordings create groove through beat subdivisions and subversion of expected microtiming patterns. The primary method for analysis is a comparison of beat-upbeat ratios (BUR) and upbeat-beat-ratios (UBR) throughout the measure to determine any trends or significant outliers. The analysis shows that these performers, despite their different backgrounds, share certain microtiming trends and patterns (particularly in the performance of beats 2 and 3, and the presence of phenomenal accents on beat 2), which could therefore be understood as characteristic features of the Gaelic style. Conversely, I also demonstrate that while conforming to those patterns, each musician nevertheless has idiosyncrasies of microtiming that distinguish them from each other.
Detection of frequency spacings in the young O-type binary HD 46149 from CoRoT photometry
Creators: name: Degroote, P.
name: Briquet, M.
name: Auvergne, M.
name: Simon-Diaz, S.
name: Aerts, C.
name: Noels, A.
name: Rainer, M.
name: Hareter, M.
name: Poretti, E.
name: Mahy, L.
name: Oreiro, R.
name: Vuckovic, M.
name: Smolders, K.
name: Baglin, A.
name: Baudin, F.
name: Catala, C.
name: Michel, E.
name: Samadi, R.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Using the CoRoT space based photometry of the O-type binary HD46149, stellar atmospheric effects related to rotation can be separated from pulsations, because they leave distinct signatures in the light curve. This offers the possibility of characterising and exploiting any pulsations seismologically. Combining high-quality space based photometry, multi-wavelength photometry, spectroscopy and constraints imposed by binarity and cluster membership, the detected pulsations in HD46149 are analyzed and compared with those for a grid of stellar evolutionary models in a proof-of-concept approach. We present evidence of solar-like oscillations in a massive O-type star, and show that the observed frequency range and spacings are compatible with theoretical predictions. Thus, we unlock and confirm the strong potential of this seismically unexplored region in the HR diagram.
description: 11 pages, 12 figures, accepted for publication in A&A
A Critical Analysis of the Legal Effect of the Phrase Subject to Contract in Property Law Conveyancing
Creators: name: Ayanjompe, George
name: Chigbo, Clement
Publisher: name: figshare
Year: 2020
Subjects: subject: 180124 Property Law (excl. Intellectual Property Law)
subject: FOS: Law
subject: Law
subject: 180105 Commercial and Contract Law

description: In ordinary practical contract law context, the conventional legal reasoning isthat the insertion of the phrase "subject to contract" in a contract automaticallymeans that that particular contract is unenforceable until a formal contract hasbeen entered into. However, the question may be asked whether this is alwaysthe case. Are there peculiar instances in which the court would disregard theconventional reasoning and enforce an agreement made subject to contract? Thisarticle therefore intends to examine the seemingly rigid legal construct of thephrase "subject to contract," the current position of law on this effect of thisphrase and the instances in which agreements may be enforced regardless of thepresence of the “subject to contract" phrase.
Impronta del feminismo en el escenario sociopolítico latinoamericano
Creators: name: Acosta Reveles, Irma Lorena
Publisher: name: figshare
Year: 2021
Subjects: subject: Anthropology
subject: FOS: Sociology
subject: Gender studies
subject: Sociology
subject: 160609 Political Theory and Political Philosophy
subject: FOS: Political science
subject: 220210 History of Philosophy
subject: FOS: Philosophy, ethics and religion
subject: 160806 Social Theory

description: Por su enorme significado para el acontecer político, socioeconómico y cultural en el presente, y en aras de construir horizontes de vida más justos, se hace necesario poner en discusión las vindicaciones feministas gestadas en la región y que se propagan en el último cuarto de siglo. Es preciso ponderar la naturaleza de sus propuestas, las barreras para instalarse en la agenda gubernamental y sus aportes al conocimiento mediante teorizaciones que convocan múltiples opresiones (étnicas, epistémicas, de índole capitalista y patriarcal). Se revisan en concreto las enunciaciones y praxis de “Las mujeres que luchan” del Ejercito Zapatista de Liberación Nacional (EZLN) y del Parlamento Plurinacional y Popular de Mujeres y Organizaciones Feministas de Ecuador. Se argumenta que sus resistencias apuntan –en varios sentidos- a un sincretismo con movimientos por la defensa de los bienes comunes, el territorio, el medio ambiente y la autodeterminación de los pueblos originarios.
Novel application to estimate the mass-loss and the dust-formation rates in O-type gamma-ray binaries using near-infrared photometry
Creators: name: Moritani, Yuki
name: Kawachi, Akiko
name: Okazaki, Atsuo T.
name: Chimasu, Sho
name: Yoshida, Hiromi
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We have performed the near-infrared photometric monitoring observations of two TeV gamma-ray binaries with O-stars (LS 5039 and 1FGL J1018.6-5856), using IRSF/SIRIUS at SAAO, in order to study the stellar parameters and their perturbations caused by the binary interactions. The whole orbital phase was observed multiple times and no significant variabilities including orbital modulations are detected for both targets. Assuming that the two systems are colliding wind binaries, we estimate the amplitude of flux variation caused by the difference in the optical depth of O-star wind at inferior conjunction, where the star is seen through the cavity created by pulsar wind, and other orbital phases without pulsar-wind intervention. The derived amplitude is <0.001 mag, which is about two orders of magnitude smaller than the observed upper limit. Also using the upper limits of the near-infrared variability, we for the first time obtain the upper limit of the dust formation rate resulting from wind-wind collision in O-star gamma-ray binaries.
description: 7 figures, 2 tables, Accepted to publications in PASJ
An Outer Commutator Multiplier and Capability of Finitely Generated Abelian Groups
Creators: name: Parvizi, Mohsen
name: Mashayekhy, Behrooz
Publisher: name: arXiv
Year: 2010
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20E34, 20E10, 20F12, 20F18

description: We present an explicit structure for the Baer invariant of a finitely generated abelian group with respect to the variety $[\mathfrak{N}_{c_1},\mathfrak{N}_{c_2}]$, for all $c_2\leq c_1\leq 2c_2$. As a consequence we determine necessary and sufficient conditions for such groups to be $[\mathfrak{N}_{c_1},\mathfrak{N}_{c_2}]$-capable. We also show that if $c_1\neq 1\neq c_2$, then a finitely generated abelian group is $[\mathfrak{N}_{c_1},\mathfrak{N}_{c_2}]$-capable if and only if it is capable. Finally we show that $\mathfrak{S}_2$-capability implies capability but there is a finitely generated abelian group which is capable but is not ${\mathfrak S}_2$-capable.
description: 19 pages
Low-stretch trees for network visualization
Creators: name: McKnight, Rebecca Linda
Publisher: name: University of British Columbia
Year: 2015

description: Low-stretch trees are spanning trees which provide approximate distance preservation for edges in the original graph by minimizing stretch. We explore the application of these trees to network visualization. In particular, we present a novel edge bundling technique, LSTB, that computes edge bundles explicitly and efficiently and does not rely on fixed vertex positions. This approach is in contrast to previous methods, which require the user to provide a layout of the input graph. We introduce an abstract framework for edge bundling methods, which provides a unifying formalization of bundling terminology and techniques, as well as a classification of such methods. Based on this framework, LSTB provides algorithmic support for sophisticated visual encodings, including dynamic layout adjustment and interactive bundle querying. In addition, we explore the use of the multiplicative weights update method to compute a distribution over low-stretch trees in order to achieve low stretch for all edges in expectation, rather than on average. We present the results of using this distribution in place of a single low-stretch tree as a routing graph for LSTB. While the distribution provides better stretch guarantees, we find that from a visual perspective a single low-stretch tree provides a better routing graph for the LSTB edge bundling application.
The possibility of determining open-cluster parameters from BVRI photometry
Creators: name: Monteiro, Hektor
name: Dias, Wilton S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: In the last decades we witnessed an increase in studies of open clusters of the Galaxy, especially because of the good determination for a wide range of values of parameters such as age, distance, reddening, and proper motion. The reliable determination of the parameters strongly depends on the photometry available and especially on the U filter, which is used to obtain the color excess E(B-V) through the color-color diagram (U-B) by (B-V) by fitting a zero age main-sequence. Owing to the difficulty of performing photometry in the U band, many authors have tried to obtain E(B-V) without the filter. But because of the near linearity of the color-color diagrams that use the other bands, combined with the fact that most fitting procedures are highly subjective (many done "by eye") the reliability of those results has always been questioned. Our group has recently developed, a tool that performs isochrone fitting in open-cluster photometric data with a global optimization algorithm, which removes the need to visually perform the fits and thus removes most of the related subjectivity. Here we apply our method to a set of synthetic clusters and two observed open clusters (Trumpler 1 and Melotte 105) using only photometry for the BVRI bands. Our results show that, considering the cluster structural variance caused only by photometric and Poisson sampling errors, our method is able to recover the synthetic cluster parameters with errors of less than 10% for a wide range of ages, distances, and reddening, which clearly demonstrates its potential. The results obtained for Trumpler 1 and Melotte 105 also agree well with previous literature values.
description: 5 pages, 5 figures, accepted for publication in Astronomy&Astrophysics
Special #Session: 5G-PPP Phase 3 introduction & ICT-19-2018 info-session 5G-VINNI (5G Verticals INNovation Infrastructure)
Creators: name: Grønsund, Pål
Publisher: name: Zenodo
Year: 2018

description: 5G-VINNI (5G Verticals INNovation Infrastructure) is a project accepted for grant in ICT-17 to

	Build an open large scale 5G End-to-End facility that can
	demonstrate that key 5G network KPIs can be met KPIs (capacity, ubiquity, speed, latency, reliability, density of users, location accuracy,energy efficiency, service creation time, network management capex/opex)
	be validated, accessed and used by vertical industries (e.g. in ICT-19projects) to test use cases and validate 5G KPIs.
Environmental adaptation and stress response of Salmonella enterica in peanut oil, peanuts and chia seeds
Creators: name: Fong, Karen
Publisher: name: University of British Columbia
Year: 2015

description: In North America, outbreaks of Salmonella in recent years have been linked to low-water activity (aw) foods, such as tree nuts, peanut butter and chia seed powder. The unusual emergence in microenvironments that should otherwise limit bacterial survival highlights the need for the elucidation of mechanisms that enhance Salmonella survival in low aw foods, which are currently poorly understood. The purpose of this study was to evaluate the response of Salmonella enterica to two stressors commonly encountered in low-aw food processing, desiccation and heat treatment. Five strains representing different serotypes of S. enterica were inoculated onto food matrices with varying aw: peanut oil (aw 0.521 ± 0.003), peanuts (aw 0.321 ± 0.20) and chia seeds (aw 0.585 ± 0.003) to identify survival characteristics in low-aw environments. To assess the effect of stress pre-adaptation on survival, peanut oil-desiccated cells and/or cells shocked at 45°C were subsequently subjected to 70°C. Lastly, the relative expression levels of five stress response or virulence genes (i.e. invA, fadA, otsB, rpoE and dnaK) were assessed following heat treatment or desiccation using quantitative polymerase chain reaction (qPCR). S. enterica exhibited long-term survival in the low-aw foods (up to 105 days) and showed a strain-specific response. S. Hartford and S. Thompson were identified as persistent in these low-aw foods, while Typhimurium was identified as the least persistent serotype. Furthermore, cells pre-exposed to six days of desiccation in peanut oil and/or 45°C heat for three minutes exhibited significantly (p<0.05) higher resistance to 70°C heat treatment. qPCR revealed various degrees of up- and down-regulation amongst the characterized genes and across different strains under the desiccation and heat treatments. Serotypes Hartford and Thompson displayed the highest up-regulation in otsB and fadA, genes vital in desiccation response, consistent with their persistence in the survival assays. Moreover, differential expression of dnaK, a gene important for heat-tolerance was also observed across all Salmonella strains. The current research emphasizes the adaptable nature of S. enterica to stresses encountered in low-aw food processing. Additionally, unique stress response characteristics among Salmonella strains highlight the need for tailored mitigation strategies regarding high-risk Salmonella strains in the food industry.
Fundamental effective temperature measurements for eclipsing binary stars -- IV. Selection of new benchmark stars and first results for HD 22064
Creators: name: Maxted, P. F. L.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: I describe the selection and initial characterisation of 20 eclipsing binary stars that are suitable for calibration and testing of stellar models and data analysis algorithms used by the PLATO mission and spectroscopic surveys. The binary stars selected are F-/G-type dwarf stars with M-type dwarf companions that contribute less than 2% of the flux at optical wavelengths. The light curves typically show well-defined total eclipses with very little variability between the eclipses. I have used near-infrared spectra obtained by the APOGEE survey to measure the spectroscopic orbit for both stars in HD22064. Combined with an analysis of the TESS light curve, I derive the following masses and radii: $M_1 = 1.35 \pm 0.03 M_{\odot}$, $M_2 = 0.58 \pm 0.01 M_{\odot}$, $R_1 = 1.554 \pm 0.014 R_{\odot}$, $R_2 = 0.595 \pm 0.008 R_{\odot}$. Using $R_1$ and the parallax from Gaia EDR3, I find that the primary star's angular diameter is $θ= 0.1035 \pm 0.0009 $ mas. The apparent bolometric flux of the primary star is ${\mathcal F}_{\oplus,0} = (7.51\pm 0.09)\times10^{-9}$ erg cm$^{-2}$ s$^{-1}$. Hence, this F2V star has an effective temperature $T_{\rm eff,1} = 6763{\rm\,K} \pm 39{\rm \,K}$. HD22064 is an ideal benchmark star that can be used for "end-to-end" tests of the stellar parameters measured by large-scale spectroscopic surveys, or stellar parameters derived from asteroseismology with PLATO. The techniques described here for HD22064 can be applied to the other eclipsing binaries in the sample in order to create an all-sky network of such benchmark stars.
description: 13 pages, 9 figures. Accepted for publication in MNRAS. Revised and re-submitted version. Includes supplementary information in the source files. arXiv admin note: text overlap with arXiv:2205.01466
Some Properties of the Schur Multiplier with Algebraic Topological Approach
Creators: name: Mashayekhy, Behrooz
name: Mirebrahimi, Hanieh
Publisher: name: arXiv
Year: 2010
Subjects: subject: Algebraic Topology (math.AT)
subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 57M07, 55Q20, 55P20, 20C25

description: In this paper, using a relationship between the Schur multiplier of a group $G$, the fundamental group, and the second homology group of the Eilenberg-MacLane space of $G$, we present new proofs for some famous properties of the Schur multiplier and its structure for the free product and the direct product with an algebraic topological approach. Also, we try to find the Schur multiplier of a free amalgamated product in terms of Schur multipliers of its factors, which is a new result.
description: 8 pages
Accurate smooth pursuit eye movements lead to more accurate manual interceptions
Creators: name: Fooken, Jolande
Publisher: name: University of British Columbia
Year: 2015

description: In ball sports, athletes are taught to keep their eyes on the ball to catch or hit it successfully. This intuitive field experience has already been studied in the laboratory, indicating that tracking a moving object with smooth pursuit eye movements enhances our ability to predict the object’s trajectory in time and space. Similarly, intercepting a moving object critically relies on motion prediction. Here we assessed the functional significance of eye movements for manual interceptions. In a novel paradigm, we asked observers (n=32) to track a small moving dot, backprojected onto a translucent screen, and to intercept it with their index finger in a designated ‘hit zone’. Hereby, only the first part (100-300 ms) of the trajectory was shown. Thus, observers had to extrapolate the trajectory and intercept its assumed position anywhere within the hit zone. Results show that better pursuit (low eye position and velocity error, high velocity gain, few catch-up saccades of small amplitude) lead to more accurate interceptions. A Hazard analysis yielded two interception strategies: Early interceptors relied on tracking quality and memory feedback given at the end of each trial, while late interceptors depended more on tracking smoothness, small initial saccades, and accurate eye latencies. Early interceptions (less time of invisibility) yielded smaller 2D interception error, while the interception timing was better for longer periods of smooth tracking (later interceptions). A regression model tree identified low tracking error and small saccadic eye movements as those eye parameters predicting accurate interceptions best. Not only do observers benefit from smooth pursuit eye movements during manual interception, but the interception accuracy also scales with the quality of the eye movements.
Right-angled Coxeter polytopes, hyperbolic 6-manifolds, and a problem of Siegel
Creators: name: Everitt, Brent
name: Ratcliffe, John G.
name: Tschantz, Steven T.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: By gluing together the sides of eight copies of an all-right angled hyperbolic 6-dimensional polytope, two orientable hyperbolic 6-manifolds with Euler characteristic -1 are constructed. They are the first known examples of orientable hyperbolic 6-manifolds having the smallest possible volume.
description: 32 pages
Spiral Bragg gratings for TM mode silicon photonics
Creators: name: Chen, Zhitian
Publisher: name: University of British Columbia
Year: 2015

description: In this thesis, we demonstrate long transverse magnetic (TM) Bragg gratings wrapped compactly using spiral waveguides on the silicon-on-insulator (SOI) platform. We developed three types of TM spiral Bragg grating waveguides (SBGWs) including uniform spiral Bragg grating (U-SBGWs), phaseshifted spiral Bragg grating (P-SBGWs), and chirped spiral Bragg gratings (C-SBGWs). Our spiral waveguides are space-efficient, requiring an area of only 189 x 189 μm² to accommodate 1 cm long Bragg grating waveguides and, thus, are less susceptible to fabrication non-uniformities. Due to these factors, the TM U-SBGWs are able to successfully obtain narrow bandwidths and high extinction ratios (ERs), as narrow as 0.09 nm and as large as 52 dB respectively. Also, the TM P-SBGWs can obtain sharp resonance peaks with high quality factors of 78790. Finally, we demonstrate the TM C-SBGWs, which exhibit group delays that are linear functions of the wavelengths over their passbands. Traditionally, due to the large coupling coefficients and the flexibility for achieving desired spectral characteristics, short Bragg grating waveguides for transverse electric (TE) modes on the SOI platform have been developed for applications in optical communication and sensing systems. In contrast, TM modes Bragg gratings on SOI platform have small coupling coefficients and, therefore, the grating lengths need to be much longer than TE mode devices, in order to obtain large ERs. However, such TM mode Bragg gratings can achieve very narrow bandwidths. Creating long gratings in regular straight waveguides suffer from the fabrication non-uniformity effects caused by the wafer thickness. As is shown here, spiral-shaped waveguides can be used to increase the grating length, while still being made using little on chip real estate, thus reducing the effects of fabrication non-uniformity.
Additional file 1 of Genome sequencing of the neotype strain CBS 554.65 reveals the MAT1–2 locus of Aspergillus niger
Creators: name: Ellena, Valeria
name: Seekles, Sjoerd J.
name: Vignolle, Gabriel A.
name: Ram, Arthur F. J.
name: Steiger, Matthias G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Aspergillus niger strains used in this study.
Non-Hermitian guided modes and exceptional points using loss-free negative-index materials
Creators: name: Wu, Li-Ting
name: Zhang, Xin-Zhe
name: Luo, Ru-Zhi
name: Chen, Jing
Publisher: name: arXiv
Year: 2023
Subjects: subject: Optics (physics.optics)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: We analyze the guided modes in coupled waveguides made of negative-index materials without gain or loss. We show that it supports non-Hermitian phenomenon on the existence of guided mode versus geometric parameters of the structure. The non-Hermitian effect is different from parity-time (PT) symmetry, and can be explained by a simple coupled-mode theory with an anti-PT symmetry. The existence of exceptional points and slow-light effect are discussed. This work highlights the potential of loss-free negative-index materials in the study of non-Hermitian optics.
Absolute calibration of photodetectors: photocurrent multiplication versus photocurrent subtraction
Creators: name: Agafonov, I. N.
name: Chekhova, M. V.
name: Iskhakov, T. Sh.
name: Penin, A. N.
name: Rytikov, G. O.
name: Shumilkina, O. A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We report testing of the new absolute method of photodetectors calibration based on the difference-signal measurement for two-mode squeezed vacuum by comparison with the traditional absolute method based on the coincidence counting. Using low-gain parametric down conversion we have measured the quantum efficiency of a counting detector by both methods. The difference-signal method was adapted for the counting detectors by taking into account the dead-time effect.
description: 3 pages, 2 figures, submitted to Optics Letters
Analysis of ultrafast magnetization switching dynamics in exchange-coupled ferromagnet-ferrimagnet heterostructures
Creators: name: Polley, Debanjan
name: Chatterjee, Jyotirmoy
name: Jang, Hyejin
name: Bokor, Jeffrey
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Magnetization switching in ferromagnets has so far been limited to the current-induced spin-orbit-torque effects. Recent observation of helicity-independent all-optical magnetization switching in exchange-coupled ferromagnet ferrimagnet heterostructures expanded the range and applicability of such ultrafast heat-driven magnetization switching. Here we report the element-resolved switching dynamics of such an exchange-coupled system, using a modified microscopic three-temperature model. We have studied the effect of i) the Curie temperature of the ferromagnet, ii) ferrimagnet composition, iii) the long-range RKKY exchange-coupling strength, and iv) the absorbed optical energy on the element-specific time-resolved magnetization dynamics. The phase-space of magnetization illustrates how the RKKY coupling strength and the absorbed optical energy influence the switching time. Our analysis demonstrates that the threshold switching energy depends on the composition of the ferrimagnet and the switching time depends on the Curie temperature of the ferromagnet as well as RKKY coupling strength. This simulation anticipates new insights into developing faster and more energy-efficient spintronics devices.
Additional file 2 of Genome sequencing of the neotype strain CBS 554.65 reveals the MAT1–2 locus of Aspergillus niger
Creators: name: Ellena, Valeria
name: Seekles, Sjoerd J.
name: Vignolle, Gabriel A.
name: Ram, Arthur F. J.
name: Steiger, Matthias G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Table S2. List of primers used in this study.