cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Detecting topological phases via survival probabilities of edge Majorana fermions
Creators: name: Wang, Yucheng
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the evolutions of edge Majorana fermions (MFs) and unveil that they can be used to char- acterize different topological phases and study the topological phase transitions. For some limiting cases of the evolution process for the one-dimensional Kitaev model and Su-Schrieffer-Heeger (SSH) model, we give analytical expressions of the survival probabilities of the edge MFs, which indicates that different topological phases correspond to different zero point numbers of the defined survival probabilities at some times. For a general case, we consider a dimerized Kitaev model and the Kitaev chain with disorder chemical potential and numerically calculate the survival probabilities of two edge correlation MFs. Our results show that both of them equal to zero, one of them equals to zero at some times or neither of them equal to zero correspond to the SSH-like topological, topological superconductor and trivial phases respectively.
Ranunculus falcatus Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus falcatus

description: Ranunculus falcatus, spec. nov.
 35. Ranunculus foliis filiformi-ramosis, calycibus appendiculatis. Hort. ups. 157. Sauv. monsp. 205.
 Myosuros foliis ramosis. Hort. cliff. 117. Roy. lugdb. 492.
 Melampyrum luteum minimum. Bauh. pin. 234.
 Ranunculus ceratocephalus, seminibus falcatis in spicam adactis. Moris. hist. 2. p.440. s.4. t.28. f.22.
 Habitat inter segetes Europae australis. ☉
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 556, DOI: 10.5281/zenodo.3931989
Basic N-Body Modelling of the Evolution of Globular Clusters. I. Time Scaling
Creators: name: Aarseth, S. J.
name: Heggie, D. C.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We consider the use of N-body simulations for studying the evolution of rich star clusters (i.e. globular clusters). The dynamical processes included in this study are restricted to gravitational (point-mass) interactions, the steady tidal field of a galaxy, and instantaneous mass loss resulting from stellar evolution. With evolution driven by these mechanisms, it is known that clusters fall roughly into two broad classes: those that dissipate promptly in the tidal field, as a result of mass loss, and those that survive long enough for their evolution to become dominated by two-body relaxation. The time scales of the processes we consider scale in different ways with the number of stars in the simulation, and the main aim of the paper is to suggest how the scaling of a simulation should be done so that the results are representative of the evolution of a `real' cluster. We investigate three different ways of scaling time. One of these is appropriate to the first type of cluster, i.e. those that dissipate rapidly, and similarly a second scaling is appropriate only to the second (relaxation-dominated) type. We also develop a hybrid scaling which is a satisfactory compromise for both types of cluster. Finally we present evidence that the widely used Fokker-Planck method produces models which are in good agreement with N-body models of those clusters which are relaxation dominated, at least for N-body models with several thousand particles, but that the Fokker-Planck models evolve too fast for clusters which dissipate promptly.
description: 24 pages, 3 figures, MNRAS, in press
Gravitational Quantum Well as an Effective Quantum Heat Engine
Creators: name: Santos, Jonas F. G.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this work the gravitational quantum well is used to model an effective two level system and to perform two thermodynamic cycles, the isogravitational and the isoenergetic ones. It is shown that the isogravitational is independent of the scale parameter whereas the isoenergetic has a dependence on the eigenstates chosen to form the cycle. An equivalent equation for the isoenergetic cycle is also obtained, which is similar to the equation of state for an isothermal process of an ideal gas. This equation reinforces the concept of energy bath, where the temperature is replaced by the energy into the expression of efficiency.
Multipole analysis of spin observables in vector meson photoproduction
Creators: name: Savkli, Cetin
name: Tabakin, Frank
name: Yang, Shin Nan
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A multipole analysis of vector meson photoproduction is formulated as a generalization of the pseudoscalar meson case. Expansion of spin observables in the multipole basis and behavior of these observables near threshold and resonances are examined.
description: 15 pages, latex, 2 figures
Ceratocephala falcata Pers.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ceratocephala
Ceratocephala falcata

description: Ranunculus falcatus Linnaeus, Species Plantarum 1: 556. 1753.
"Habitat inter segetes Europae australis." RCN: 4098.
Lectotype (Benson in Amer. Midl Naturalist 52: 364. 1954): Herb. Linn. No. 715.71 (LINN).
Current name: Ceratocephala falcata (L.) Pers. (Ranunculaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 786, DOI: 10.5281/zenodo.291971
Cytokines and epigenetic regulation of matrix metalloproteinases in tuberculosis
Creators: name: Moores, Rachel Clare
Publisher: name: Imperial College London
Year: 2013

description: Tuberculosis (TB) remains a leading cause of death globally. Some of the morbidity and mortality associated with TB arises from excessive or inappropriate immune activation in response to infection. In pulmonary TB tissue destruction, cavitation and fibrosis drive disease transmission and chronic lung dysfunction. The matrix metalloproteinases (MMPs) are host enzymes controlling extracellular matrix turnover, immune cell recruitment and activation, and they play a key role in the pathology of TB. This project explores the regulatory mechanisms controlling MMP expression in TB using a tissue culture model of respiratory epithelial cell and macrophage responses to Mycobacterium tuberculosis (Mtb). The major human collagenase MMP-1 and its activator MMP-3 are expressed in response to Mtb stimulation. The influence of exogenously added cytokines IL-4, IL-10, IL-13, TGFβ and IFNγ on MMP expression is investigated to examine how immunopathology is driven by acquired immune responses. Epigenetic mechanisms regulating MMP expression in response to Mtb are examined using inhibitors of histone deacetylases (HDACs) and histone acetyltransferases, HDAC siRNA and chromatin immunoprecipitation assays. Mtb-induced collagenase expression by epithelial cells and macrophages is selectively inhibited by the Th2 cytokines IL-4 and IL-13, but unaffected by IL-10. TGFβ enhances epithelial cell MMP secretion but does not affect macrophage MMP expression. IFNγ has divergent effects, driving epithelial cell MMP secretion but inhibiting MMP-1 and -3 expression in macrophages. The intracellular pathways mediating these effects are explored. Mtb-driven MMP expression is sensitive to HDAC and HAT inhibition, and altered HDAC expression is observed in Mtb-stimulated cells. Chromatin immunoprecipitation reveals changes in histone acetylation at the MMP-1 promoter in Mtb-stimulated epithelial cells. In pulmonary TB, production of matrix-degrading MMPs by epithelial cells and macrophages is modulated by Th2 cytokines and IFNγ. Key MMPs implicated in pulmonary immunopathology are subject to epigenetic regulatory mechanisms, which may represent potential targets for selective MMP inhibition.
Control of particle propagation beyond the uncertainty limit by interference between position and momentum
Creators: name: Hofmann, Holger F.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: As shown in Phys. Rev. A 96, 020101(R) (2017), it is possible to demonstrate that quantum particles do not move along straight lines in free space by increasing the probability of finding the particles within narrow intervals of position and momentum beyond the "either/or" limit of 0.5 using constructive quantum interference between a component localized in position and a component localized in momentum. The probability of finding the particle in a corresponding spatial interval at a later time then violates the lower bound of the particle propagation inequality which is based on the validity of Newton's first law. In this paper, the problem of localizing the two state components in their respective target intervals is addressed by introducing a set of three coefficients that describe the localization of arbitrary wavefunctions quantitatively. This characterization is applied to a superposition of Gaussians, obtaining a violation of the particle propagation inequality by more than 5 percent if the width of the Gaussian wavefunction is optimized along with the size of the position and momentum intervals. It is shown that the violation of the particle propagation inequality originates from the fundamental way in which quantum interferences relate initial position and momentum to the future positions of a particle, indicating that the violation is a fundamental feature of causality in the quantum limit.
description: 17 pages, including 5 figures, improved introduction of the defect probability and more detailed discussion of the relation between Gaussian variances and localization parameters
Magnetic flares in accretion disc coronae and the Spectral States of black hole candidates: the case of GX 339-4
Creators: name: Di Matteo, T.
name: Celotti, A.
name: Fabian, A. C.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a model for the different X-ray spectral states displayed by Galactic Black Hole Candidates (GBHC). We discuss the physical and spectral implications for a magnetically structured corona in which magnetic flares result from reconnection of flux tubes rising from the accretion disk by the magnetic buoyancy instability. Using observations of one of the best studied examples, GX339-4, we identify the geometry and the physical conditions characterizing each of these states. We find that, in the Soft state, flaring occurs at small scale heights above the accretion disk. The soft thermal-like spectrum is the result of heating and consequent re-radiation of the hard X-rays produced by such flares. The hard tail is produced by Comptonization of the soft field radiation. Conversely, the hard state is the result of flares triggered high above the underlying accretion disk which produce X-rays via Comptonization of either internal synchrotron radiation or soft disk photons. The spectral characteristics of the different states are naturally accounted for by the choice of geometry: when flares are triggered high above the disk the system is photon-starved, hence the hard Comptonized spectrum of the hard state. Intense flaring close to the disk greatly enhances the soft-photon field with the result that the spectrum softens. We interpret the two states as being related to two different phases of magnetic energy dissipation. In the Soft state, Parker instability in the disk favours the emergence of large numbers of relatively low magnetic field flux tubes. In the hard state, only intense magnetic fields become buoyant. The model can also qualitatively account for the observed short timescale variability and the characteristics of the X-ray reflected component of the hard state.
description: submitted to MNRAS, Feb. 1998, 10 pages, 3 figures in MNRAS LaTex style
The Ontological Emergence of Fluctuations in Pure Time Theory
Creators: name: Allou, Essam
Publisher: name: Zenodo
Year: 2025
Subjects: Pure Time Theory
PTT
PLU
Principle of Logical Unicity
Ontological Primacy
Emergence of Structure
Temporal Fluctuations
Scalar Field Dynamics
Genesis of Density
Cosmological Foundations
Quantum Gravity

description: This paper addresses a subtle yet fundamental question within the Pure Time Theory (PTT) framework:how can primordial fluctuations of the scalar field T_relax emerge without relying on any pre-existing structures or densities?

We demonstrate that pure time, as the ontological root of existence, inherently carries dynamical tendencies that naturally generate local instabilities, independently of any material background.These intrinsic fluctuations initiate the sequential emergence of proto-densities, spacetime geometry, and physical laws, following a coherent logical progression:

Pure Time → T_relax → g_mu_nu → rho.

This mechanism fully preserves the Principle of Logical Unicity (PLU) and requires no external assumptions.Finally, while T_relax defines the measurable frontier of scientific exploration, the deeper essence of pure time itself transcends empirical investigation—calling for both scientific rigor and intellectual humility.
Nuclear Compton scattering in the $Δ$-resonance region with polarized photons
Creators: name: Pasquini, B.
name: Boffi, S.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Nuclear Compton scattering in the $Δ$-resonance region is reconsidered within the framework of the $Δ$-hole model. The different role of the resonant and non-resonant contributions to the transition amplitudes is discussed and their effect is investigated by comparing the results of calculation with recent data also taken with polarized photons.
description: 22 pages, LaTeX, 7 figures, postscript files available from the Authors
Multiple Regressions of a Malcolm Baldrige’s Patient Safety Models
Creators: name: Nursal, Dien Gusta Anggraini
name: Mulyana, Nana
name: Rizanda Machmud
name: Eryati Darwin
Publisher: name: figshare
Year: 2018
Subjects: subject: 111707 Family Care
subject: FOS: Health sciences
subject: Health Care
subject: 111709 Health Care Administration
subject: 111708 Health and Community Services
subject: 111717 Primary Health Care
subject: 111799 Public Health and Health Services not elsewhere classified

description: This research proposed to develop patient safety models in primary health care and provide a possible modelto implementated. Primary health care in Indonesia battling in assessment of risk reduction strategy becausedifficulty in identifying adverse event and there are no model or guidance for patient safety in primaryhealth care yet. The patient safety model can be framed with Baldrige Health Care Criteria for performanceexcellence. Basic Emergency Obstetric Care was an critical health care in Indonesia for reduce maternaldeath by early detection of maternal complication. So, this study focus to develop patient safety modelin basic emergency obstetric care bases on Baldrige criteria. We conducted a cross sectional study, datacollected through a likert scale questionnaire from 194 respondent, there were doctors, nurses, midwifes,pharmacist, and medical report officer from six basic emergency obstetric care. Data analysis by linearregression and multiple regression to determined the most suitable variable to the models. The result showsthat incident detection, mitigation, health workers workload and commitment, internal audit are variables fora patient safety model development. It is recommended to futher researcher to developed module for patientsafety training in primary health care.
Kinetic template-guided tethering of fragments
Creators: name: Nonoo, Rebecca Helen
Publisher: name: Imperial College London
Year: 2013

description: This thesis is composed of two separate projects: Kinetic Template-Guided Tethering of Fragments and Design and Synthesis of a Chemical Probe to Dissect the Cellular Signalling Cascade leading to Cyclin D1 Degradation after DNA Damage. Kinetic Template-Guided Tethering of Fragments The development of a novel methodology for the site-directed discovery of small molecule, protein-binding ligands is described. The protein of interest, with a cysteine thiol (either native or engineered) adjacent to the desired binding pocket, is incubated with mixtures of low molecular weight compounds (fragments) modified with either an acrylamide or a vinyl sulfonamide capture group. Any ligand within the mixture that binds within the pocket brings the capture group into close proximity with the cysteine thiol, promoting a conjugate addition reaction at an increased rate over the background reaction. The capture reaction is designed to be slow, such that during the time course of an experiment, no adduct formation is observed unless the reaction is templated by the protein. By this method, binding ligands are rapidly identified by mass spectrometry analysis of the crude reaction mixtures. The methodology has been termed ‘kinetic template-guided tethering’. Design and Synthesis of a Chemical Probe to Dissect the Cellular Signalling Cascade leading to Cyclin D1 Degradation after DNA Damage An inhibitor described within the literature was found to attenuate the reduction of cyclin D1 after DNA damage to cells. In order to implement a two-step chemical proteomics strategy to find the molecular target of this inhibitor, a synthesis of the compound with an alkyne appendage was required. The alkyne acts as a functional handle for attachment of a reporter molecule in cells via the Huisgen cycloaddition (‘Click’) reaction. The design and synthesis of this inhibitor with the alkyne appendage is described.
Node dynamics on graphs: dynamical heterogeneity in consensus, synchronisation and final value approximation for complex networks
Creators: name: O'Clery, Neave
Publisher: name: Imperial College London
Year: 2013

description: Here we consider a range of Laplacian-based dynamics on graphs such as dynamical invariance and coarse-graining, and node-specific properties such as convergence, observability and consensus-value prediction. Firstly, using the intrinsic relationship between the external equitable partition (EEP) and the spectral properties of the graph Laplacian, we characterise convergence and observability properties of consensus dynamics on networks. In particular, we establish the relationship between the original consensus dynamics and the associated consensus of the quotient graph under varied initial conditions. We show that the EEP with respect to a node can reveal nodes in the graph with increased rate of asymptotic convergence to the consensus value as characterised by the second smallest eigenvalue of the quotient Laplacian. Secondly, we extend this characterisation of the relationship between the EEP and Laplacian based dynamics to study the synchronisation of coupled oscillator dynamics on networks. We show that the existence of a non-trivial EEP describes partial synchronisation dynamics for nodes within cells of the partition. Considering linearised stability analysis, the existence of a nontrivial EEP with respect to an individual node can imply an increased rate of asymptotic convergence to the synchronisation manifold, or a decreased rate of de-synchronisation, analogous to the linear consensus case. We show that high degree 'hub' nodes in large complex networks such as Erdős-Rényi, scale free and entangled graphs are more likely to exhibit such dynamical heterogeneity under both linear consensus and non-linear coupled oscillator dynamics. Finally, we consider a separate but related problem concerning the ability of a node to compute the final value for discrete consensus dynamics given only a finite number of its own state values. We develop an algorithm to compute an approximation to the consensus value by individual nodes that is ϵ close to the true consensus value, and show that in most cases this is possible for substantially less steps than required for true convergence of the system dynamics. Again considering a variety of complex networks we show that, on average, high degree nodes, and nodes belonging to graphs with fast asymptotic convergence, approximate the consensus value employing fewer steps.
Modelling land cover change in tropical rainforests
Creators: name: Rosa, Isabel Maria Duarte
Publisher: name: Imperial College London
Year: 2013

description: Tropical deforestation is one of the most important drivers of biodiversity loss and carbon emissions. This thesis seeks to analyse the dynamics of tropical deforestation and develop a probabilistic model that predicts land cover change (LCC) in the tropics. The main findings from the analysis of the Brazilian Amazon deforestation dynamics are that large clearings comprised progressively smaller amounts of total annual deforestation while the number of smaller clearings remained unchanged over time. These changes were coincident with the implementation of conservation policies by the government. The review of LCC models presented here showed that this modelling community would benefit from improving: the openness to share model inputs, code and outputs; model validations; and standardised frameworks to be used for model comparisons. The modelling framework developed aimed to tackle the limitations found before and two scenarios of deforestation in the Brazilian Amazon were simulated. For both scenarios forest next to roads and areas already deforested were found to be more likely to be deforested. States in the south and east of the region showed high predicted probability of losing nearly all forest outside of protected areas by 2050. The release of carbon to the atmosphere is an important consequence of tropical deforestation. Even if deforestation had ended in 2010 there would still be large quantities of carbon to be released. The amount of carbon released immediately is higher than the one committed for future release in the first few years of analysis, but presently these accounted for at least two-thirds of total carbon emissions. Finally, the drivers of LCC were found to vary among transition types, but less so through time. The accuracy of the model predictions was heavily dependent on the year calibrated, suggesting that a widespread reliance on single calibration time period may be providing biased predictions of future LCC.
Reminiscences of Joshua Logan, 1980
Publisher: name: Columbia University
Year: 2021
Subjects: Motion picture producers and directors
Theatrical producers and directors
Theater--Production and direction
Acting
Motion pictures--Production and direction
Method acting

description: Childhood; early impressions of theater and film; Culver Military Academy, 1922-27; Princeton University: acting and directing with Triangle Club, Unversity Players; decadence of Berlin, 1931; study with Stanislavsky in Russia, 1931; early acting, directing and production jobs in New York theater and Hollywood; plays and films: MR. ROBERTS, SOUTH PACIFIC, and PICNIC; philosophy about hits and directing; impressions of numerous composers, producers and actors, including Henry Fonda, James Stewart, Charlie Leatherbee, Margaret Sullavan, Kurt Weill
Magnetic reconnection: flares and coronal heating in Active Galactic Nuclei
Creators: name: Di Matteo, T.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A magnetically-structured accretion disk corona, generated by buoyancy instability in the disk, can account for observations of flare--like events in Active Galactic Nuclei. We examine how Petschek magnetic reconnection, associated with MHD turbulence, can result in a violent release of energy and heat the magnetically closed regions of the corona up to canonical X-ray emitting temperatures. X-ray magnetic flares, the after effect of the energy released in slow shocks, can account for the bulk of the X-ray luminosity from Seyfert galaxies and consistently explain the observed short-timescale variability.
description: revised version, 6 pages, 1 figures in MNRAS LaTex style
Pion flow and antiflow in relativistic heavy-ion collisions
Creators: name: Li, Bao-An
name: Ko, Che Ming
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Within the framework of a relativistic transport model (ART) for heavy-ion collisions at AGS energies, we study the transverse flow of pions with respect to that of nucleons using two complementary approaches. It is found that in central collisions pions develop a weak flow as a result of the flow of baryon resonances from which they are produced. On the other hand, they have a weak antiflow in peripheral collisions due to the shadowing of spectators. Furthermore, it is shown that both pion flow and antiflow are dominated by those with large transverse momenta.
description: Phys. Rev. C, Rapid communication, in press. Figures are available from the authors upon request
Ranunculus ficaria Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus ficaria

description: Ranunculus ficaria, spec. nov.
 9. Ranunculus foliis cordatis angulatis petiolatis. Fl. suec. 460. Hort. cliff. 228. Mat. med. 274. Roy. lugdb. 490. Dalib. paris. 167.
 Chelidonia rotundifolia minor. Bauh. pin. 167.
 Chelidonium minus. Fuchs. hist. 866.
 Chelidonia rotundifolia major. Bauh. pin. 167. prodr. 137.
 Habitat in Europae ruderatis, ambrosis, spongiosis. ♃
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 550, DOI: 10.5281/zenodo.3931989
Additional file 1: of Physical Activity after Cardiac EventS (PACES) â a group education programme with subsequent text-message support designed to increase physical activity in individuals with diagnosed coronary heart disease: study protocol for a randomised controlled trial
Creators: name: Herring, Louisa
name: Dallosso, Helen
name: Chatterjee, Sudesna
name: Bodicoat, Danielle
name: Schreder, Sally
name: Khunti, Kamlesh
name: Yates, Tom
name: Seidu, Sam
name: Hudson, Ian
name: Davies, Melanie
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Developmental Biology
Cancer
Science Policy
Mental Health

description: Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 Checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 120Â kb)
DAPK2 is a novel modulator of trail-induced apoptosis and it regulates oxidative stress in cancer cells by preserving mitochondrial function
Creators: name: Schlegel, Christoph Richard
Publisher: name: Imperial College London
Year: 2014

description: Targeting molecules involved in Tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) -mediated signalling has been hailed by many as a potential magic bullet to efficiently kill cancer cells, with little side effects on normal cells. Indeed, initial clinical trials showed that antibodies against TRAIL receptors, death receptor (DR) 4 and DR5 are well tolerated by cancer patients. Despite the initial efficacy issues in the clinical setting, novel approaches to trigger TRAIL-mediated apoptosis are being developed and its clinical potential is being reappraised. Unfortunately, many patients develop resistance to TRAIL-induced apoptosis and there is thus impetuous for identifying additional resistance mechanisms that may be targetable and usable in combination therapies. Here, we show that the death associated protein kinase (DAPK) 2 is a modulator of TRAIL signalling. DAPK2 is a serine/threonine kinase that belongs to the DAPK family. Like DAPK1, it has been implicated in programmed cell death, the regulation of autophagy and developmental processes. Ablation of DAPK2 using RNAi causes phosphorylation of NF-κB and its transcriptional activity in several cancer cell lines. This then leads to the induction of a variety of NF-κB target genes, which includes DR4 and DR5. DR4 and DR5 protein expression is correspondingly increased on the cell surface and this leads to the sensitisation of resistant cells to TRAIL-induced killing. As DAPK2 is a kinase, it is imminently druggable and our data thus offer a novel avenue to overcome TRAIL-resistance in the clinic. We have additionally identified a new role for DAPK2 in the regulation of mitochondrial integrity. RNAi-mediated depletion of DAPK2 leads to a number of metabolic changes, including a significantly decreased rate of oxidative phosphorylation in combination with an overall destabilised mitochondrial membrane potential. This phenotype is further corroborated by an increase in the production of mitochondrial superoxide anions and general oxidative stress. This role of DAPK2 is completely novel and could impact significantly on the understanding of DAPK2’s function in physiology and disease.
Light deflection by Damour-Solodukhin wormholes and Gauss-Bonnet theorem
Creators: name: Övgün, Ali
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, using the recent method proposed by Ono, Ishihara and Asada (OIA) who extend the idea of Gibbons and Werner to the stationary and axisymmetric case, we apply the Gauss-Bonnet theorem to the optical metric of the non-rotating and rotating Damour-Solodukhin wormholes spacetimes to study the weak gravitational lensing by these objects. Furthermore, we study the strong gravitational lensing by the non-rotating Damour-Solodukhin wormholes using the Bozza's method to see the differences between the weak lensing and the strong lensing. We demonstrate the relation between the strong deflection angle and quasinormal modes of the Damour-Solodukhin wormholes. Interestingly it is found that the wormhole parameter $λ$, affects the deflection of light in strong and weak limits compared to the previous studies of gravitational lensing by Schwarzschild black holes. Hence, the results provide a unique tool to shed light on the possible existence of wormholes.
description: 8 pages, two-column. Accepted for publication in Physical Review D
title: ADCO, Ordre cistercien : comptes (1403-1423) (11 H 1161), f. 00060
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161), f. 00060, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
Ranunculus ficaria Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus ficaria

description: Ranunculus ficaria Linnaeus, Species Plantarum 1: 550. 1753.
"Habitat in Europae ruderatis, umbrosis, spongiosis." RCN: 4069.
Lectotype (Benson in Amer. Midl. Naturalist 52: 369. 1954): Herb. Linn. No. 715.12 (LINN).
Current name: Ranunculus ficaria L. (Ranunculaceae).
Note: Laegaard (in Nordic J. Bot. 20: 525. 2001) reviewed the history of this name, accepted Benson’s typification (rather than the later one made by Sell in Watsonia 20: 42-43. 1994), and validated subsp. fertilis Clapham for the diploid variant.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 786, DOI: 10.5281/zenodo.291971
Numerical simulations of protostellar encounters I. Star-disc encounters
Creators: name: Boffin, H. M. J.
name: Watkins, S. J.
name: Bhattal, A. S.
name: Francis, N.
name: Whitworth, A. P.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: It appears that most stars are born in clusters, and that at birth most stars have circumstellar discs which are comparable in size to the separations between the stars. Interactions between neighbouring stars and discs are therefore likely to play a key role in determining disc lifetimes, stellar masses, and the separations and eccentricities of binary orbits. Such interactions may also cause fragmentation of the discs, thereby triggering the formation of additional stars. We have carried out a series of simulations of disc-star interactions using an SPH code which treats self-gravity, hydrodynamic and viscous forces. We find that interactions between discs and stars provide a mechanism for removing energy from, or adding energy to, the orbits of the stars, and for truncating the discs. However, capture during such encounters is unlikely to be an important binary formation mechanism. A more significant consequence of such encounters is that they can trigger fragmentation of the disc, via tidally and compressionally induced gravitational instabilities, leading to the formation of additional stars. When the disc-spins and stellar orbits are randomly oriented, encounters lead to the formation of new companions to the original star in 20% of encounters. If most encounters are prograde and coplanar, as suggested by simulations of dynamically-triggered star formation, then new companions are formed in approximately 50% of encounters.
description: 17 pages, submitted to MNRAS; low resolution figures only
OISO - OCÉAN INDIEN SERVICE D'OBSERVATION
Creators: name: METZL Nicolas
Publisher: name: Sismer
Year: 1998

description: L'observation et la compréhension des variations saisonnière, interannuelle et décennale du cycle du carbone océanique sont primordiales pour estimer le bilan contemporain de carbone à l'échelle planétaire et comprendre son évolution, évaluer l'acidification des océans et  valider les modèles climatiques prédictifs (e.g., Global Carbon Project, Global Ocean Acidification Observation Network, IPCC). Afin de compléter les observations internationales (IOCCP, GO-SHIPS), le programme OISO (labellisé S.O./INSU en Juillet 1997) a pour objectif de maintenir sur une longue durée l'observation du CO2 océanique dans l'Océan Indien Sud et Austral. Chaque année, durant les campagnes conduites à bord du Marion-Dufresne, sont collecté des mesures de CO2 et paramètres associés (T, S, DIC, TA, O2, nutritifs, Chl-a, 13C, 18O) dans les eaux de surface et la colonne d'eau. Ces données sont régulièrement transmises dans des bases de données dédiées (CORIOLIS, OCADS, GOA-ON, JasADCP) et les synthèses internationales (bases SOCAT, GLODAP).  Des collaborations avec les équipes françaises ou internationales sont engagées depuis 1998, tant pour des études de processus (e.g. N2 fixation, espèces phytoplanctoniques), le largage de flotteurs (Carioca, ARGO, bio-ARGO) ou l'utilisation des données pour l'estimation du bilan de carbone global et valider les modèles océaniques (projets GCP, SOCOM). Le S.O OISO a été, et est associé, à des programmes français (INSU/LEFE, SOERE/GREATGASES, MAP-IO), européens (CARBOOCEAN, CARBOCHANGE) et internationaux (IGBP, SOLAS, IMBER, GO-SHIPS, CLIVAR, GOA-ON, SOCCOM, SOOS, IIOE-2). Depuis 1998, les résultats du S.O. OISO ont été le support de 30 thèses, plus de 380 publications, et référencés dans les rapports du GIEC (2013, 2019).Les informations et liste des campagnes sont consultables sur: https://caraus.ipsl.jussieu.fr/oisoaccueil.html
MOESM1 of Developmental Stage-Specific Hepatocytes Induce Maturation of HepG2 Cells by Rebuilding the Regulatory Circuit
Creators: name: Li, Yanning
name: Liu, Demei
name: Zong, Yanhong
name: Qi, Jinsheng
name: Li, Bin
name: Liu, Kun
name: Xiao, Hui
Publisher: name: figshare
Year: 2015
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary material, approximately 977 KB.
OHA-SIS-BIO - OBSERVATOIRE HYDROACOUSTIQUE
Creators: name: ROYER Jean-Yves
Publisher: name: Sismer
Year: 2009

description: OHA-SIS-BIO - Observatoire HydroAcoustique de la SISmicité et de la BIOdiversité de l'océan Indien - est un programme hydroacoustique à long terme pour surveiller l'activité sismique des dorsales et l'activité vocale des grands mammifères marins dans l'océan Indien austral. Un réseau d'hydrophones autonomes immergés dans l'axe du canal SOFAR (9 mouillages) a éré déployé et entretenu annuellement de 2010 à debut 2023, entre La Réunion, Crozet, Kerguelen et Amsterdam, profitant des voyages annuels du N.O. Marion Dufresne vers ces îles australes.Le réseau d'hydrophones était conçu pour surveiller en continu l'activité sismique associée à trois dorsales océaniques à taux d'expansion contrastés (16 à 70 mm/an) et à la déformation intraplaque dans le sud du bassin central indien. Cette approche s'avère très efficace pour détecter et localiser les séismes de faible magnitude (>3), qui échappent aux réseaux sismologiques terrestres, et pour distinguer les événements tectoniques et magmatiques. Les objectifs étaient de caractériser l'activité sismique de dorsales médio-océaniques à taux d'ouverture ultra-lent, lent et intermédiaire, ainsi que la distribution temporelle et spatiale de la déformation intraplaque.Cet observatoire était également conçu pour surveiller l'activité vocale des grands rorquals à fanons. L'acoustique passive s'avère en effet un outil très efficace pour surveiller la présence de ces mammifères marins acoustiquement très actifs. Au moins 5 populations de rorquals bleus ont été détectées par notre réseau. L'objectif était d'améliorer les connaissances sur la présence, l'abondance et les migrations saisonnières de ces grands mammifères marins, classés en danger, sur plusieurs cycles annuels dans l'océan Indien austral.Ces données ont aussi apporté des informations inattendues sur l'état de mer et les icebergs (vêlage, collision, dislocation). Ces deux applications nécessitent également de longues séries temporelles pour valider les modèles de prévision de l'état de mer ou pour suivre l'évolution du bruit ambiant océanique (naturel ou artificiel).Tous ces objectifs ont en commun de nécessiter des enregistrements hydroacoustiques basse fréquence (< 120 Hz) et des séries temporelles continues aussi longues que possible pour être représentatives du régime sismique des dorsales, de l'activité des baleines ou des variations du bruit ambiant, dans ces régions éloignées et peu accessibles de l'océan.Ce programme a été soutenu par la Flotte Océanographique Française, le CNRS (INSU), l'Université de Brest et le Conseil Régional de Bretagne.Rorqual commun et iceberg tabulaire au large du plateau sud des Kerguelen (photo prise en janvier 2010 par 58°S depuis le N.O. Marion Dufresne). Carte bathymétrique de l'océan Indien avec le réseau d'hydrophones autonomes OHASISBIO (cercles blancs) et les stations hydroacoustiques permanentes IMS-CTBTO (étoiles)
Ranunculus flammula Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus flammula

description: Ranunculus flammula, spec. nov.
 1. Ranunculus foliis ovato-lanceolatis petiolatis, caule declinato. Hort. cliff. 228. Fl. suec. 458. Roy. lugdb. 489. Hall. helv. 322. Dalib. paris. 163.
 Ranunculus foliis ovato-oblongis integerrimis, caule procumbente. Fl. lapp. 325.
 Ranunculus longifolius palustris minor. Bauh. pin. 180.
 Flammula Ranunculus. Dod. pempt. 432.
 β. Ranunculus palustris, foliis serratis. Bauh. pin. 180.
 Habitat in Europae pascuis udis. ♃
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 548, DOI: 10.5281/zenodo.3931989
Measuring the triple Higgs self-couplings in two Higgs doublet model
Creators: name: Sonmez, Nasuf
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The determination of the Higgs self-coupling in the Standard Model is one of the primary motivations among all the future lepton colliders. Extending the scalar sector of the Standard Model by a new Higgs doublet with a quadratic Higgs potential gives many new features to the model, and most importantly additional Higgs self-couplings emerge. Measuring these couplings is the only way to reconstruct the shape of the scalar potential. In this study, the numerical analysis of several scattering processes is carried out for the two-Higgs-doublet model to determine all these Higgs self-couplings. These processes are selected among various possible combinations of additional Higgs states. The computation is carried out in the exact alignment limit ($s_{βα}=1$). The distribution of the cross sections is presented regarding the polarization of the incoming beams and up to $\sqrt{s}=3\text{ TeV}$. A strategy for extracting the Higgs self-couplings are considered in 2HDM and at the future lepton colliders. Possible final states that could be used for each of the processes are investigated using the decays of the final state particles.
description: 16 pages, 7 figures
Program for Generating Tables of SU(3) Coupling Coefficients
Creators: name: Kaeding, Thomas A.
name: Williams, H. Thomas
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A C-Language program which tabulates the isoscalar factors and Clebsch-Gordan coefficients for products of representations in SU(3) is presented. These are efficiently computed using recursion relations, and the results are presented in exact precision as square roots of rational numbers. Output is in LaTeX format.
description: LaTeX, 29 pages, no figures
Reminiscences of Judy Quine 1988
Publisher: name: Columbia University
Year: 2020
Subjects: Women authors
Authors
Vietnam War, 1961-1975
Presidents--Election--1976.--United States

description: First memories of Allard Lowenstein; Lowenstein at Grace Kelly wedding, Monaco 1956; Lowensteins̀ political activities in California and involvement with film industry figures; participation in first Lowenstein congressional campaign; effect on Lowenstein of visit to Vietnam; observations on Lowensteins̀ political and ethical philosophies; allegations of connection between Lowenstein and Central Intelligence Agency; involvement with Edmund G. (Jerry) Brown, Jr. presidential campaign, 1976; memories of Dennis Sweeney; observations on Lowensteins̀ marriage; memories of Lowensteins̀ death and funeral
Magnetic suppression of zonal flows on a beta plane
Creators: name: Constantinou, Navid C.
name: Parker, Jeffrey B.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Fluid Dynamics (physics.flu-dyn)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Zonal flows in rotating systems have been previously shown to be suppressed by the imposition of a background magnetic field aligned with the direction of rotation. Understanding the physics behind the suppression may be important in systems found in astrophysical fluid dynamics, such as stellar interiors. However, the mechanism of suppression has not yet been explained. In the idealized setting of a magnetized beta plane, we provide a theoretical explanation that shows how magnetic fluctuations directly counteract the growth of weak zonal flows. Two distinct calculations yield consistent conclusions. The first, which is simpler and more physically transparent, extends the Kelvin-Orr shearing wave to include magnetic fields and shows that weak, long-wavelength shear flow organizes magnetic fluctuations to absorb energy from the mean flow. The second calculation, based on the quasilinear, statistical CE2 framework, is valid for arbitrary wavelength zonal flow and predicts a self-consistent growth rate of the zonal flow. We find that a background magnetic field suppresses zonal flow if the bare Alfven frequency is comparable to or larger than the bare Rossby frequency. However, suppression can occur for even smaller magnetic fields if the resistivity is sufficiently small enough to allow sizable magnetic fluctuations. Our calculations reproduce the $η/B_0^2 = \text{const.}$ scaling that describes the boundary of zonation, as found in previous work, and we explicitly link this scaling to the amplitude of magnetic fluctuations.
description: 17 pages, 7 figures
title: ADCO, Ordre cistercien : comptes (1499-1515) (11 H 1162), f. 00450
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Ordre cistercien : comptes (1499-1515), Archives départementales de la Côte-d'Or, (11 H 1162). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1499-1515), Archives départementales de la Côte-d'Or, (11 H 1162), f. 00450, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v