cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Exploração do tecido espaço-tempo com a robótica: perspectivas e desafios.
Creators: name: Amarante
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Robotics
subject: Robótica quântica
subject: Theoretical physics
subject: Quantum physics
subject: Física teórica

description: A robótica avançada tem desempenhado um papel fundamental na exploração espacial e no entendimento das interações entre robôs e as complexidades do espaço-tempo. Este artigo propõe um estudo teórico pioneiro sobre como robôs podem interagir com distorções no tecido espaço-temporal, abordando as implicações físicas e matemáticas dessa interação, além de explorar como essas tecnologias podem ser aplicadas em futuras missões espaciais e investigações sobre a natureza fundamental do universo. Utilizando as equações da relatividade geral e princípios da dinâmica relativística, este estudo busca entender as exigências tecnológicas para desenvolver robôs capazes de navegar e operar em ambientes com extrema curvatura espaço-temporal, como buracos negros e ondas gravitacionais. A inclusão de sensores precisos, sistemas de navegação autônoma e propulsão relativística será essencial para o avanço dessas tecnologias, baseando-se em investigações teóricas recentes tanto no Brasil quanto no exterior.
Optical properties of atomically thin transition metal dichalcogenides: Observations and puzzles
Creators: name: Koperski, M.
name: Molas, M. R.
name: Arora, A.
name: Nogajewski, K.
name: Slobodeniuk, A. O.
name: Faugeras, C.
name: Potemski, M.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Recent results on the optical properties of mono- and few-layers of semiconducting transition metal dichalcogenides are reviewed. Experimental observations are presented and discussed in the frame of existing models, highlighting the limits of our understanding in this emerging field of research. We first introduce the representative band structure of these systems and their interband optical transitions. The effect of an external magnetic field is then considered to discuss Zeeman spectroscopy and optical pumping experiments, both revealing phenomena related to the valley degree of freedom. Finally, we discuss the observation of single photon emitters in different types of layered materials, including wide band gap hexagonal boron nitride. While going through these topics, we try to focus on open questions and on experimental observations, which do not yet have a clear explanation.
description: 41 pages, 18 figures
THE ROLE OF INTERNATIONAL ORGANIZATIONS IN WATER RESOURCE MANAGEMENT IN CENTRAL ASIA
Creators: name: DJALILOVA, Malika
Publisher: name: Zenodo
Year: 2024

description: This study examines the role of international organizations in managing water resources in Central Asia from a geopolitical and institutional perspective. It evaluates the contributions of key organizations such as the UN, World Bank, and OSCE, identifies the challenges faced, and proposes policy recommendations for enhancing regional cooperation and sustainability. The mixed-methods approach includes qualitative case studies, interviews, and quantitative surveys to provide a comprehensive analysis of the impact and effectiveness of international interventions.
A broad assessment of Eremurus spectabilis M. Bieb: chemical and elemental composition, total phenolic and antimicrobial activity analysis, and quantum chemical calculations of radical scavenging potential
Creators: name: Tegin, İbrahim
name: Hallaç, Bülent
name: Sabancı, Nazmiye
name: Sadik, Betül
name: Fidan, Mehmet
name: Yabalak, Erdal
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology
subject: Virology

description: Eremurus spectabilis M. Bieb was extensively investigated experimentally and theoretically, including the antioxidant properties of compounds such as flavonoids, hydroxycinnamic acid derivatives, hydroxybenzoic acid derivatives, and organic acids. Antioxidant activity was investigated using the Density Functional Theory (DFT) method based on three known mechanisms: hydrogen atom transfer (HAT), single electron transfer followed by proton transfer (SET-PT), and sequential proton loss electron transfer (SPLET). Subcritical water extraction (SWE), soxhlet extraction (SE), and solvent extraction (SOE) techniques were applied in the extraction process. Malic acid was the major compound with an extract concentration of 38,532.84 ± 1849.58 µg analyte/kg, total phenolics, and free radical scavenging activity were 10.67 mg gallic acid/mL extract and 73.89% per mg/mL extract, respectively. P, Fe, Na, Mg, K, and Ca were the main elements. The antibacterial activity of E. spectabilis against seven bacteria was evaluated, and it was found to be higher than the commercial antibiotics P10 and AMC30.
Exploração do tecido espaço-tempo com a robótica: perspectivas e desafios
Creators: name: Amarante, REIS, E. G. A.
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Robotics
subject: Robótica quântica
subject: Theoretical physics
subject: Quantum physics
subject: Física teórica

description: A robótica avançada tem desempenhado um papel fundamental na exploração espacial. Este artigo propõe um estudo teórico sobre como robôs podem interagir com distorções no tecido espaço-temporal, abordando as implicações físicas e matemáticas dessa interação. Utilizando as equações da relatividade geral e princípios da dinâmica relativística, este estudo busca entender as exigências tecnológicas para desenvolver robôs capazes de navegar e operar em ambientes com extrema curvatura espaço-temporal, como buracos negros e ondas gravitacionais. A inclusão de sensores precisos, sistemas de navegação autônoma e propulsão relativística será essencial para o avanço dessas tecnologias, baseando-se em investigações teóricas recentes tanto no Brasil quanto no exterior.
Exploração do tecido espaço-tempo com a robótica: perspectivas e desafios
Creators: name: Amarante
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Robotics
subject: Robótica quântica
subject: Theoretical physics
subject: Quantum physics
subject: Física teórica

description: A robótica avançada tem desempenhado um papel fundamental na exploração espacial. Este artigo propõe um estudo teórico sobre como robôs podem interagir com distorções no tecido espaço-temporal, abordando as implicações físicas e matemáticas dessa interação. Utilizando as equações da relatividade geral e princípios da dinâmica relativística, este estudo busca entender as exigências tecnológicas para desenvolver robôs capazes de navegar e operar em ambientes com extrema curvatura espaço-temporal, como buracos negros e ondas gravitacionais. A inclusão de sensores precisos, sistemas de navegação autônoma e propulsão relativística será essencial para o avanço dessas tecnologias, baseando-se em investigações teóricas recentes tanto no Brasil quanto no exterior.
J0906+6930: a radio-loud quasar in the early Universe
Creators: name: Zhang, Yingkang
name: An, Tao
name: Frey, Sandor
name: Gabanyi, Krisztina E.
name: Paragi, Zsolt
name: Gurvits, Leonid I.
name: Sohn, Bong Won
name: Jung, Taehyun
name: Kino, Motoki
name: Lao, Baoqiang
name: Lu, Yang
name: Mohan, Prashanth
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Radio-loud high-redshift quasars (HRQs), although only a few of them are known to date, are crucial for the studies of the growth of supermassive black holes (SMBHs) and the evolution of active galactic nuclei (AGN) at early cosmological epochs. Radio jets offer direct evidence of SMBHs, and their radio structures can be studied with the highest angular resolution using Very Long Baseline Interferometry (VLBI). Here we report on the observations of three HRQs (J0131-0321, J0906+6930, J1026+2542) at z>5 using the Korean VLBI Network and VLBI Exploration of Radio Astrometry Arrays (together known as KaVA) with the purpose of studying their pc-scale jet properties. The observations were carried out at 22 and 43 GHz in 2016 January among the first-batch open-use experiments of KaVA. The quasar J0906+6930 was detected at 22 GHz but not at 43 GHz. The other two sources were not detected and upper limits to their compact radio emission are given. Archival VLBI imaging data and single-dish 15-GHz monitoring light curve of J0906+6930 were also acquired as complementary information. J0906+6930 shows a moderate-level variability at 15 GHz. The radio image is characterized by a core-jet structure with a total detectable size of ~5 pc in projection. The brightness temperature, 1.9x10^{11} K, indicates relativistic beaming of the jet. The radio properties of J0906+6930 are consistent with a blazar. Follow-up VLBI observations will be helpful for determining its structural variation.
description: accepted for publication in Monthly Notices of the Royal Astronomical Society Main Journal. 8 pages, 3 figures
Polymerized-Type I Collagen Induces a High Quality Cartilage Repair in a Rat Model of Osteoarthritis
Creators: name: Almonte-Becerril M
name: Enríquez AB
name: Kourí JB
name: Furuzawa-Carballeda J2
Publisher: name: figshare
Year: 2017
Subjects: Behavioral Neuroscience

description: Background: Osteoarthritis (OA) is a chronic, degenerative and inflammatory disease. It is characterized by progressive deterioration of articular cartilage. It is the most common disabling rheumatic pathology in adults older than 45 years, and there is no specific treatment. Objectives: Based on the rationale that in vitro polymerized-type I collagen induces chondrocytes proliferation, up-regulates the cartilage extracellular matrix proteins and down-regulates proinflammatory cytokines, we decided to evaluate its effect on cartilage repair in a rat model of OA. Methods: Thirty Wistar male rats with partial meniscectomy were subjected to daily high impact exercise during 3 weeks. Rats were randomly allocated into 5 groups a) training control, b)sham/operated control, c) toxicity control, d) OA treated with 4 intraarticular (IA) injections of placebo, and e) OA treated with 4 IA injections of polymerized-type I collagen. Weight, temperature and thickness of the knee were measured. Histological and radiological analysis was also performed. Type I and II collagen as well as, MMP13 expression was determined by immunofluorescence. Results: Clinimorphometric analysis showed a higher temperature and thickness of the knee in OA/placebo vs. OA/polymerized-type I collagen treated rats. Radiological and histological analysis demonstrated that polymerized-type I collagen but not placebo preserved joint cavity structure and proteoglycans content and induced an increase of 2 to 4 fold type II collagenexpressing chondrocytes whereas it inhibited type I collagen and MMP13 producing chondrocytes. Conclusion: The results suggest that polymerized-type I collagen is safe and effective chondroprotective biodrug with disease modifying effects. It induces high quality cartilage repair.
Reduction of ovarian reserves and activation of necroptosis to in vivo air pollution exposures
Creators: name: Namvar, Zahra
name: Tehrani, Fahimeh Ramezani
name: Shahsavani, Abbas
name: Khodagholi, Fariba
name: Hashemi, Seyed Saeed
name: Binayi, Fateme
name: Salimi, Mina
name: Abdollahifar, Mohammad-Amin
name: Hopke, Philip K.
name: Mohseni-Bandpei, Anoushiravan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: We investigated the association between air pollution and changes in ovarian follicles, anti-mullerian hormone (AMH) levels, the occurrence of necroptosis cell death by activation of receptor-interacting protein kinase 3 (RIPK3) and, the activation of mixed lineage kinase domain-like (MLKL) proteins. Forty-two female Wistar rats were divided into three groups of 14 each, which were exposed to real-ambient air, filtered air and purified air (control) in two periods of 3 and 5 months. The results showed that the number of ovarian follicles decreased in the group exposed to real-ambient air versus the control group (P < 0.0001). The trend of age-related AMH changes with respect to exposure to air pollutants was affected and its levels decreased after 3 months of exposure. The MLKL increased in the group exposed to the real-ambient air compared to the control group (P = 0.033). Apparently long-term exposure to air pollution can reduce ovarian reserves.
Floating Dislocated Elbow: A Case Report
Creators: name: El Ayoubi .A
name: Maanouk .R
name: Krite .A
name: El Ghadraoui .R
name: Lahsika .M
name: Benssassi, A.
name: Senhaji .S
name: El Idrissi .M
name: El Ibrahimi .A
name: Elmrini .A
Publisher: name: figshare
Year: 2018
Subjects: Survey Results

description: Floating dislocated elbow is an extremely rare injury, only a few cases were reported. We present here a case of the constellation of skeletal trauma which associates a proximal humerus fracture, distal radius fracture and elbow dislocation. Through the literature review we will include clinical, radiological, therapeutic and functional results of this injury
Index appearance record for transforming Rabin automata into parity automata
Creators: name: Křetínský, Jan
name: Meggendorfer, Tobias
name: Waldmann, Clara
name: Weininger, Maximilian
Publisher: name: arXiv
Year: 2017
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Formal Languages and Automata Theory (cs.FL)
subject: FOS: Computer and information sciences

description: Transforming deterministic $ω$-automata into deterministic parity automata is traditionally done using variants of appearance records. We present a more efficient variant of this approach, tailored to Rabin automata, and several optimizations applicable to all appearance records. We compare the methods experimentally and find out that our method produces smaller automata than previous approaches. Moreover, the experiments demonstrate the potential of our method for LTL synthesis, using LTL-to-Rabin translators. It leads to significantly smaller parity automata when compared to state-of-the-art approaches on complex formulae.
МОДИФИКАТОРЫ ЛЕЙКОТРИЕНОВ ПРИ ВИРУС-ИНДУЦИРОВАННОЙ БРОНХИАЛЬНОЙ АСТМЕ У ДЕТЕЙ (ЧАСТЬ 1)
Creators: name: БУЛГАКОВА В.А.
Publisher: name: Аллергология и Иммунология в Педиатрии
Year: 2013

description: Acute respiratory infection exacerbates inflammation in bronchial asthma. Recurrent respiratory tract infections are often the cause of lack of control over the symptoms of the disease. As a separate clinical phenotype of asthma in children excrete the virus-induced asthma. Effective anti-inflammatory drugs for the prevention of virus-induced exacerbations of asthma at this stage seem leukotriene receptor antagonists.
Additional file 1 of Model selection for the sound speed perturbation of GNSS-A using the widely applicable Bayesian information criterion (WBIC)
Creators: name: Watanabe, Shun-ichi
name: Ishikawa, Tadashi
name: Nakamura, Yuto
name: Yokota, Yusuke
Publisher: name: figshare
Year: 2025
Subjects: subject: Statistics
subject: FOS: Mathematics

description: Additional file 1.
Spermacosides a and B, two new triterpenoid saponins from Spermacoce ocymoides burm.f.
Creators: name: Nguyen, Ngoc-Dung
name: Vo, Thi-Nga
name: Nguyen, Thi-Hong-Nhung
name: Nguyen, Thi-Ngoc-Nuong
name: Nguyen, Ngọc-Tin
name: Nguyen, Kim-Phi-Phung
name: Nguyen, Thi-Anh-Tuyet
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Two new triterpenoid saponins, named spermacosides A–B (1 − 2), together with two known oleanane-type triterpenoid saponins, 3-O-β-D-xylopyranosyl-(1→3)-β-D-glucopyranosylbayogenin (3) and 3-O-β-D-glucopyranosylbayogenin (4), were isolated from the ethyl acetate extract of Spermacoce ocymoides Burm.f. in a phytochemical investigation. Their chemical structures were elucidated by spectroscopic data analysis (1D and 2D NMR, and HR-ESI-MS), as well as comparison with reported data. All these compounds were evaluated for inhibiting nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 cells. Among them, 1 showed a slight effect with an IC50 value of 108.65 ± 7.91 µM, and compounds 2–4 were inactive.
title: ADCO, Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.1 (début XIIIe siècle), Cart. 166 (11 H 64), 136 folios, f. 0123r
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.1 (début XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 166 (11 H 64), 136 folios, f. 0123r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.1 (début XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 166 (11 H 64), 136 folios, f. 0123r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Additional file 1 of Performance of a point-of-care ultrasound platform for artificial intelligence-enabled assessment of pulmonary B-lines
Creators: name: Labaf, Ashkan
name: Åhman-Persson, Linda
name: Husu, Leo Silvén
name: Smith, J. Gustav
name: Ingvarsson, Annika
name: Evaldsson, Anna Werther
Publisher: name: figshare
Year: 2025
Subjects: Medicine
Biological Sciences not elsewhere classified
Cancer
Science Policy
Mental Health
Hematology

description: Supplementary Material 1
Chaos Engineering
Creators: name: Basiri, Ali
name: Behnam, Niosha
name: de Rooij, Ruud
name: Hochstein, Lorin
name: Kosewski, Luke
name: Reynolds, Justin
name: Rosenthal, Casey
Publisher: name: arXiv
Year: 2017
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Modern software-based services are implemented as distributed systems with complex behavior and failure modes. Many large tech organizations are using experimentation to verify the reliability of such systems. We use the term "Chaos Engineering" to refer to this approach, and discuss the underlying principles and how to use it to run experiments.
A new bufadienolide from Bufo gargarizans Cantor
Creators: name: Zhu, Li-Jie
name: Qiao, Li-Man
name: Wu, Jian
name: Wang, Zhong-Hua
name: Ye, Xiao-Jing
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Bufo gargarizans Cantor (B. gargarizans) is the most widely distributed and abundant species of toad in China. Bufadienolides and indole alkaloids have cardiotonic and anti-tumor activities and are important pharmacological components of B. bufo gargarizans. In this experiment, a novel compound (1) and two known compounds (2 and 3) were isolated and identified from the dry skin of B. bufo gargarizans, both of which are bufadienolides. Various column chromatography methods were used to separate and purify the extract from the dried skin of B. bufo gargarizans. Accurate molecular weights were measured by HR-ESI-MS, and the chemical structure of the compounds was determined by NMR spectrometers. The structures were named as (2β,5β,16α)-2,5,16-trihydroxide bufa-14,20,22 dienolide (1), gamabufotalin (2) and desacetylbufotalin (3). In vitro cytotoxic activity assay indicated that compound 1 showed a moderate cytotoxicity against A549 cells with IC50 value of 12.65 μM.
Additional file 1 of Highly thermal stable RNase A@PbS/ZnS quantum dots as NIR-IIb image contrast for visualizing temporal changes of microvasculature remodeling in flap
Creators: name: Yang, Yimeng
name: Chen, Mo
name: Wang, Peng
name: Sai, Liman
name: Chen, Chen
name: Qian, Pingkang
name: Dong, Shixian
name: Feng, Sijia
name: Yang, Xing
name: Wang, Hao
name: Abdou, Amr M.
name: Li, Yunxia
name: Chen, Shiyi
name: Hao, Yuefeng
name: Ma, Dongling
name: Feng, Shaoqing
name: Chen, Jun
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology
subject: Cancer

description: Additional file 1: Fig. S1. Characterization of NIR-IIb–emitting RNase A@PbS/ZnS QDs. (A) Absorption spectrum of RNase A@PbS/ZnS QDs. (B) Energy-dispersive X-ray of RNase A@PbS/ZnS QDs. (C) Selected area electron diffraction pattern of RNase A@PbS/ZnS QDs. (D) TEM images of RNase A@PbS/ZnS QDs. (E) Size-distribution of RNase A@PbS/ZnS QDs. Fig. S2. The effects of different concentrations of RNase A@PbS/ZnS QDs on MSCs viability. (a). Live/dead cell staining for MSCs (green fluorescence-live cells, red fluorescence-dead cells). Scale bars represent 50 μm. (b). Quantification analysis of MSCs viability. Fig. S3. DM the diameter of epigastric artery (A) and femoral artery (B); the blue arrows indicate the femoral artery, and the yellow arrows indicate the epigastric artery. Fig. S4. In vivo pharmacokinetics and biodistribution of RNase A@PbS/ZnS QDs in normal mice. (A) Body weight of RNase A@PbS/ZnS QDs treated mice over a period time of 21 d. (B) Time course of Pb2+ concentration in the blood of RNase A@PbS/ZnS QDs treated mice over 21 h. (C) Time course of Pb2+ concentration in the feces of RNase A@PbS/ZnS QDs treated mice. (D) Biodistribution of Pb2+ in organs. Fig. S5. In vivo biodistribution of RNase A@PbS/ZnS QDs in flap perfusion animal model mice (A) Bright field and NIR-IIb fluorescence images of various organs collected from the mice at 21 days after postinjection. (B) Quantitative analysis NIR-IIb signal intensity of various organs. Fig. S6. Representative photomicrographs of hematoxylin and eosin staining on the major organs of the mice after injection of RNase A@PbS/ZnS QDs.
Floating Dislocated Elbow: A Case Report
Creators: name: A, El Ayoubi
name: Maanouk R
name: Krite A
name: R, El Ghadraoui
name: Lahsika M
name: Benssassi A
name: Senhaji S
name: M, El Idrissi
name: A, El Ibrahimi
name: Elmrini A
Publisher: name: figshare
Year: 2017
Subjects: Survey Results

description: Floating dislocated elbow is an extremely rare injury, only a few cases were reported. We present here a case of the constellation of skeletal trauma which associates a proximal humerus fracture, distal radius fracture and elbow dislocation. Through the literature review we will include clinical, radiological, therapeutic and functional results of this injury
ПОДБОР ТЕРАПИИ ИНГАЛЯЦИОННЫМИ КОРТИКОСТЕРОИДАМИ ПРИ БРОНХИАЛЬНОЙ АСТМЕ
Creators: name: МИТРОФАНОВА Е.С.
name: СМОЛКИН Ю.С.
Publisher: name: Аллергология и Иммунология в Педиатрии
Year: 2013

description: The purpose of this article is to describe some difficulties in choosing the right inhaled corticosteroids (ICS) according to severity of asthma and patients’ concerns about it. There are given some clinical cases of asthma management in children and adults describing the diagnostic methods and the way how the needed dose of ICS was admitted. Also one of the new ICS Ciclesonide as an effective treatment of mild and severe asthma due to results of clinical trials is discussed.
Characterization of fracture energy and toughness of air plasma PDMS–PDMS bonding by T-peel testing
Creators: name: Chen, Cheng-Fu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The fracture energy, toughness and failure modes of air plasma oxidized polydimethylsiloxane (PDMS) bonding are evaluated in this paper. Each PDMS–PDMS bonded specimen was subjected to T-peel testing at a constant-displacement rate. The load–extension curve from each test was analyzed by the principle of energy balance in linearly elastic fracture mechanics, to calculate the fracture energy (critical strain energy), which is the maximal strain energy a bonded specimen can withstand without losing its assembly integrity, and toughness (surface energy), which is the bonding energy at the interface. A distribution of calculated values against the air plasma treatment parameters shows the predominant range of 0.1 to 0.4 N/mm for fracture energy and 0.1 to 0.2 N/mm for toughness. Together with an analysis of three failure modes (cohesive, adhesive, and mixed), the results suggest 0.1 N/mm as the threshold of the fracture energy for weak bonding, below which a specimen will be likely to fail through debonding. A set of treatment parameters are recommended for using air plasma to achieve strong bonding.
Electrical detection of magnetic states in crossed nanowires using the topological Hall effect
Creators: name: Tanabe, Kenji
name: Yamada, Keisuke
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We used micromagnetic simulations to investigate the spatial distributions of the effective magnetic fields induced by spin chirality in crossed nanowires with three characteristic magnetic structures: a radiated-shape, an antivortex, and a uniform-like states. Our results indicate that, unlike the anomalous Hall effect, the topological Hall effect (which is related to the spin chirality) depends on both the polarity and the vorticity. Therefore, measuring the topological Hall effect can detect both the polarity and the vorticity simultaneously in crossed nanowires. This approach may be suitable for use as an elemental technique in the quest for a next-generation multi-value memory.
ИНФИЦИРОВАНИЕ СТАФИЛОКОККОМ ПОРАЖЕННОЙ КОЖИ ДЕТЕЙ С АТОПИЧЕСКИМ ДЕРМАТИТОМ
Creators: name: КУДРЯВЦЕВА А.В.
name: МОРОЗОВА О.А.
name: САВВИНА Ю.А.
Publisher: name: Аллергология и Иммунология в Педиатрии
Year: 2013

description: The article presents the findings on the staphilococcus infection of the skin lesions in children with Atopic Dermatitis at various disease stages. The study has shown that in the illness acute phases the skin is exposed to massive staphilococcus colonization. Due to the outer glucocorsteroids treatment the skin infection with staphilococcus aureus decreases significantly, resulting in the patient's state improvement. The use of a cosmetic cream in AD remission stage allows not only to keep the skin in a good condition but to prevent its secondary colonization with staphilococcus aureus as well as the disease recurrence.
SuperMarioDomains: Generalizing to Domains with Evolving Graphics
Creators: name: Luo, Yiran
name: Feinglass, Joshua
name: Gokhale, Tejas
name: Baral, Chitta
name: Yang, Yezhou
Publisher: name: Maryland Shared Open Access Repository
Year: 2023

description: Domains in previous Domain Generalization (DG) benchmarks have been sampled from various image collections of different styles such as photographs, sketches, cartoons, paintings, product images, and etc. However, from these existing DG datasets, it is still difficult to quantify the magnitude of domain shift between different domains and relate that to the performance gap across domains. It is also unclear how to measure the overlap between different domains. Therefore, we present a new DG dataset, SuperMarioDomains, containing four domains that are derived from four chronological titles in the Mario video game franchise on four generations of video game hardware. The discrepancy between our domains is quantified in terms of image representation complexity that reflect the hardware evolution in image resolution, color palette, and presence of 3D rendering. We benchmark state-of-the-art DG algorithms under both Multi-Source and Single-Source DG settings on our dataset and find that they can only surpass the random average baseline in our dataset by at most 18.0% and 10.4% respectively. In addition, we show that adding our dataset as part of the pre-training process improves performance of existing DG algorithms on the PACS benchmark.
Stress-response transcription factors Msn2 and Msn4 couple TORC2-Ypk1 signaling and mitochondrial respiration to ATG8 gene expression and autophagy
Creators: name: Ariadne Vlahakis
name: Muniozguren, Nerea Lopez
name: Powers, Ted
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Macroautophagy/autophagy is a starvation and stress-induced catabolic process critical for cellular homeostasis and adaptation. Several Atg proteins are involved in the formation of the autophagosome and subsequent degradation of cytoplasmic components, a process termed autophagy flux. Additionally, the expression of several Atg proteins, in particular Atg8, is modulated transcriptionally, yet the regulatory mechanisms involved remain poorly understood. Here we demonstrate that the AGC kinase Ypk1, target of the rapamycin-insensitive TORC2 signaling pathway, controls ATG8 expression by repressing the heterodimeric Zinc-finger transcription factors Msn2 and Msn4. We find that Msn2 and Msn4 promote ATG8 expression downstream of the histone deacetylase complex (HDAC) subunit Ume6, a previously identified negative regulator of ATG8 expression. Moreover, we demonstrate that TORC2-Ypk1 signaling is functionally linked to distinct mitochondrial respiratory complexes. Surprisingly, we find that autophagy flux during amino acid starvation is also dependent upon Msn2-Msn4 activity, revealing a broad role for these transcription factors in the autophagy response.
Interaction of real and virtual $p\bar{p}$ pairs in $J/ψ\to p\bar{p}γ(ρ,ω)$ decays
Creators: name: Milstein, A. I.
name: Salnikov, S. G.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The $p\bar{p}$ invariant mass spectra of the processes $J/ψ\to p\bar{p}ω$, $J/ψ\to p\bar{p}ρ$, and $J/ψ\to p\bar{p}γ$ close to the $p\bar{p}$ threshold are calculated by means of the $N\bar{N}$ optical potential. The potential model for $N\bar{N}$ interaction in the $^{1}S_{0}$ state is proposed. The parameters of the model are obtained by fitting the cross section of $N\bar{N}$ scattering together with the $p\bar{p}$ invariant mass spectra of the $J/ψ$ decays. Good agreement with the available experimental data is achieved. Using our potential and the Green's function approach we also describe the peak in the $η'π^{+}π^{-}$ invariant mass spectrum in the decay $J/ψ\toγη'π^{+}π^{-}$ in the energy region near the $N\bar{N}$ threshold.
description: 13 pages, 12 figures
global monsoon time scales
Creators: name: Gangadhara Rao Irlapati
Publisher: name: Zenodo
Year: 2020
Subjects: global monsoons

description: There are many global monsoon systems, regional monsoon systems and sub-regional monsoon systems in the world. In fact each and every region and country has it’s own monsoon winds. Monsoon Time Scales for all world regions and countries are proposed and designed by me to study their regions and countries. So world scientists can make the Monsoon Time Scales and study their monsoon systems. Find out and study them just prefixing a monsoon region or country name to Monsoon Time Scale and searching in all websites just like as AUSTRALIAN MONSOON TIME SCALE. Scientists who make those Monsoon Time Scales have trouble in making it, kindly take my assistance in making the Monsoon Time Scales. Email id to contact me is gangadhar19582058@gmail.com. I will create model Monsoon Time Scales and send the same to them for study. For this, they must send the list of events of climate just like dust storms, monsoon low pressure systems etc. last 140 years since 1880 formed over their country’s regions in the procedure cited below reference. In addition to this, a certain amount should be sent for expenses. You need to design the computer model later.
description: There are many global monsoon systems, regional monsoon systems and sub-regional monsoon systems in the world. In fact each and every region and country has it's own monsoon winds. Monsoon Time Scales for all world regions and countries are proposed and designed by me to study their regions and countries. So world scientists can make the Monsoon Time Scales and study their monsoon systems. Find out and study them just prefixing a monsoon region or country name to Monsoon Time Scale and searching in all websites just like as AUSTRALIAN MONSOON TIME SCALE. Scientists who make those Monsoon Time Scales have trouble in making it, kindly take my assistance in making the Monsoon Time Scales. Email id to contact me is gangadhar19582058@gmail.com. I will create model Monsoon Time Scales and send the same to them for study. For this, they must send the list of events of climate just like dust storms, monsoon low pressure systems etc. last 140 years since 1880 formed over their country's regions in the procedure cited below reference. In addition to this, a certain amount should be sent for expenses. You need to design the computer model later.
Trans-cinnamaldehyde fumigation inhibits Escherichia coli by affecting the mechanism of intracellular biological macromolecules
Creators: name: Huang, Yuqiang
name: Zhang, Tong
name: Hu, Huiying
name: Duan, Xuejuan
name: Wu, Kegang
name: Chai, Xianghua
name: He, Dong
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Hematology
subject: Virology

description: This study aimed to determine the antibacterial mechanism of cinnamaldehyde fumigation in Escherichia coli (E. coli). Through vapour fumigation, cinnamaldehyde was confirmed to exhibit effective antibacterial activity against E. coli. The minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) were 0.25 μL/mL and 0.5 μL/mL, respectively. Based on transmission electron microscopy, the wrinkled bacterial cells observed after fumigation could be related to the leakage of intracellular substances. Laser tweezers Raman spectroscopy revealed changes in the main chain of proteins, the hydrogen bond system and spatial structure, and single- and double-stranded DNA breaks. In addition, breakage of the fatty acyl chain backbone was found to affect the vertical order degree of the lipid bilayer and cell membrane fluidity, thereby inhibiting the growth of E. coli. Overall, our findings indicate that cinnamaldehyde fumigation inhibits E. coli growth by inducing changes in intracellular biological macromolecules.
Comtrifosides A and B, two new triterpenoid saponins from the leaves of Combretum trifoliatum
Creators: name: Nguyen, Cong Thai Son
name: Vo, Thanh Hoa
name: Pham, Nguyen Kim Tuyen
name: Huynh, Bui Linh Chi
name: Ngo, Trong Nghia
name: Dang, Van Son
name: Huynh, Thi Kim Chi
name: Bui, Trong Dat
name: Nguyen, Diep Xuan Ky
name: Phan, Nhat Minh
name: Tri, Dinh
name: Nguyen, Kim Phi Phung
name: Nguyen, Tan Phat
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: The phytochemical composition of the Combretum trifoliatum leaves was studied for the first time. Two new triterpenoid saponins, named comtrifoside A (1) and comtrifoside B (2), together with two other saponins (3–4) were purified by variously chromatographic techniques. For the first time, compound 3 was informed from the Combretum genus, as well as all of the isolated compounds (1–4) were reported from C. trifoliatum. The chemical structures of them were clearly characterised using extensive UV-VIS, IR, HRMS-ESI, and NMR experimental data. The in vitro anti-inflammatory activities of 1 & 2 were examined against NO overproduction in LPS activation of RAW264.7.
Antimicrobial phytoconstituents from Azadirachta indica (neem) with potential inhibitor against FtsZ protein of Pseudomonas aeruginosa
Creators: name: Orozco-Ugarriza, Mauricio E.
name: Caldera, Nicole Paola Arrieta
name: Olivo-Martínez, Yenifer
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Pseudomonas aeruginosa is a well-known pathogen for its rapid development of multi-drug antibiotic resistance. This pathogen is responsible for numerous human diseases, particularly affecting immunocompromised and elderly patients. Hence, discovering novel therapeutics has become necessary in the fight against antimicrobial resistance. This study is focused on evaluating the potential inhibitory activity of eleven phytocompounds from Azadirachta indica against the nucleotide-binding site of the FtsZ protein of P. aeruginosa through a cheminformatics approach. FtsZ is an indispensable and highly conserved protein in prokaryotic cell division. Docking studies revealed favourable binding energies (ΔG= − 8.3 to − 5.4 kcal/mol) for all selected phytoconstituents. Finally, we selected Nimbiol (CID 11119228), as a lead compound, exhibiting a binding energy (ΔG= −7.8 kcal/mol) for the target. Based on our findings, Nimbiol shows potential as an anti-FtsZ compound, making it a promising candidate for further in vitro and in vivo investigations to assess its antimicrobial activity.
Folding of guanine quadruplex molecules -- funnel-like mechanism or kinetic partitioning? An overview from MD simulation studies
Creators: name: Šponer, Jiří
name: Bussi, Giovanni
name: Stadlbauer, Petr
name: Kührová, Petra
name: Banáš, Pavel
name: Islam, Barira
name: Haider, Shozeb
name: Neidle, Stephen
name: Otyepka, Michal
Publisher: name: arXiv
Year: 2016
Subjects: subject: Biomolecules (q-bio.BM)
subject: Biological Physics (physics.bio-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Background: Guanine quadruplexes (GQs) play vital roles in many cellular processes and are of much interest as drug targets. In contrast to the availability of many structural studies, there is still limited knowledge on GQ folding. Scope of review: We review recent molecular dynamics (MD) simulation studies of the folding of GQs, with an emphasis paid to the human telomeric DNA GQ. We explain the basic principles and limitations of all types of MD methods used to study unfolding and folding in a way accessible to non-specialists. We discuss the potential role of G-hairpin, G-triplex and alternative GQ intermediates in the folding process. We argue that, in general, folding of GQs is fundamentally different from funneled folding of small fast-folding proteins, and can be best described by a kinetic partitioning (KP) mechanism. KP is a competition between at least two (but often many) well-separated and structurally different conformational ensembles. Major conclusions: The KP mechanism is the only plausible way to explain experiments reporting long time-scales of GQ folding and the existence of long-lived sub-states. A significant part of the natural partitioning of the free energy landscape of GQs comes from the ability of the GQ-forming sequences to populate a large number of syn-anti patterns in their G-tracts. The extreme complexity of the KP of GQs typically prevents an appropriate description of the folding landscape using just a few order parameters or collective variables. General significance: We reconcile available computational and experimental studies of GQ folding and formulate basic principles characterizing GQ folding landscapes
description: \c{opyright} 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
An exploratory study of the long-term impact of difficulty kneeling after total knee replacement
Creators: name: Fletcher, Daniel
name: Moore, Andrew J.
name: Blom, Ashley W.
name: Wylde, Vikki
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology

description: Purpose: To explore the long-term impact of difficulty with kneeling and how healthcare services could be improved to help patients kneel after total knee replacement. Patients and methods: Telephone interviews were conducted with 56 patients who had extreme difficulty kneeling at 7–10 years after knee replacement. Patients were asked about reasons for difficulty kneeling, how it impacted upon their lives, and experiences of healthcare services. Responses were recorded on a standardized proforma and a descriptive content analysis performed. Results: Most people had difficulty kneeling because of pain or discomfort in the replaced knee. Many patients described how this limitation affected their daily lives, including housework, gardening, religious practices, leisure activities and getting up after a fall. Patients often adapted to these limitations by finding alternatives to kneeling, assistance from others or home adaptations. Many patients had accepted that they could not kneel, however some still expressed frustrated. Few patients had consulted with healthcare professionals about kneeling difficulties, and unmet needs included the provision of information about kneeling and post-operative physiotherapy. Interpretation: This study provides an initial insight into how difficulty kneeling after knee replacement impacts upon patientsand the need for better healthcare provision.Implications for rehabilitationRehabilitation professionals should be aware that many patients experience difficulty with kneeling after total knee replacement and that this has a long-term impact upon patients.There is a need for rehabilitation after knee replacement to address kneeling difficulties.It is suggested that this rehabilitation should be delivered early in the postoperative recovery phase and designed to address the multifactorial reasons that patients find kneeling problematic. Rehabilitation professionals should be aware that many patients experience difficulty with kneeling after total knee replacement and that this has a long-term impact upon patients. There is a need for rehabilitation after knee replacement to address kneeling difficulties. It is suggested that this rehabilitation should be delivered early in the postoperative recovery phase and designed to address the multifactorial reasons that patients find kneeling problematic.
Specific interface area in a thin layer system of two immiscible liquids with vapour generation at the contact interface
Creators: name: Pimenova, Anastasiya V.
name: Gazdaliev, Ilias M.
name: Goldobin, Denis S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: For well-stirred multiphase fluid systems the mean interface area per unit volume, or "specific interface area" $S_V$, is a significant characteristic of the system state. In particular, it is important for the dynamics of systems of immiscible liquids experiencing interfacial boiling. We estimate the value of parameter $S_V$ as a function of the heat influx $\dot{Q}_V$ to the system or the average system overheat $\langleΘ\rangle$ above the interfacial boiling point. The derived results can be reformulated for the case of an endothermic chemical reaction between two liquid reagents with the gaseous form of one of the reaction products. The final results are restricted to the case of thin layers, where the potential gravitational energy of bubbles leaving the contact interface is small compared to their surface tension energy.
description: 8 pages, 2 figures
Effect of interlayer processes on the superconducting state within t-J-U model: Full Gutzwiller wave-function solution and relation to experiment
Creators: name: Zegrodnik, Michał
name: Spałek, Józef
Publisher: name: arXiv
Year: 2017
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The Gutzwiller wave function solution of the $t$-$J$-$U$ model is considered for the bilayer high-T$_C$ superconductor by using the so-called diagrammatic expansion method. The focus is on the influence of the interlayer effects on the superconducting state. The chosen pairing symmetry is a mixture of $d_{x^2-y^2}$ symmetry within the layers and the so-called $s^{\pm}$ symmetry for the interlayer contribution. The analyzed interlayer terms reflect the interlayer electron hopping, the interlayer exchange coupling, and the interlayer pair hopping. The obtained results are compared with selected experimental data corresponding to the copper-based compound Bi-2212 with two Cu-O planes in the unit cell. For the sake of comparison, selected results for the case of the bilayer Hubbard model are also provided. This paper complements our recent results obtained for the single-plane high temperature cuprates [cf. J. Spałek, M. Zegrodnik, and J. Kaczmarczyk, Phys. Rev. B {\bf 95}, 024506 (2017)]