cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
DESIGN, SYNTHESIS, CHARACTERISATION AND BIOLOGICAL TESTING OF NEW DERIVATIVES OF HYALURONAN FOR THE PRECONDITIONING OF STEM CELLS FOR THE THERAPY OF MUSCULAR DYSTROPHIES AND THE DEVELOPMENT AND REGENERATION OF SKELETAL MUSCLE
Creators: name: GENNARI, ARIANNA
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: Regenerative medicine is the process of creating living, functional tissues to repair or replace tissue or organ functions lost due to age, disease, damage, or congenital defects. Related to regenerative medicine is field of tissue engineering. Numerous strategies currently used to engineer tissues depend on employing a specific material. These scaffolds serve as a synthetic extra cellular matrix thus to direct the growth and the formation of a desired tissue. Recent work has suggested application of mesoangioblasts for stem cell therapies for muscular dystrophy. Experiments in dystrophic mice and dogs have shown that mesoangioblasts transplantation can restore muscle function. Anyway, the possibility of using this novel strategy for the cell therapy in genetic diseases is strictly related to the capacity to expand mesoangioblasts in culture in a reproducible and efficient way. Hence, the aim of this project is to investigate the ability of the hyaluronic acid (HA) to act as a basement for cells culture; cells are in fact very sensitive to their environment and the contact with something mimicking the extra cellular matrix could, in theory, assure a better proliferation and differentiation. Hyaluronan can be chemically modified to introduce drugs, ligands or other bioactive molecules, or to cross link the linear chains affording reticulated networks. Several different methods to provide modified HA have been performed in order to develop robust protocols; specifically we focused on Sharpless cycloaddition, on the use of diisocyanates as cross linker agents and on the activation of the carboxylic acid moiety towards amines. Mesoangioblasts were cultured using HA and its derivatives as substrates to evaluate their biological influence on in vitro proliferation and differentiation. Furthermore a deep investigation concerning the kinetics of the Michael-type addition was performed. Due to its versatility, Michael addition is a precious tool for the bioconjugation often used also for HA-derivatisation. Thus we deeply studied the effect of the reagents architecture (influence of the Michael donor and acceptor), their stability and that of the Michael adducts.
Additional file 1 of Prevalence and correlates of maternal early stimulation behaviors during pregnancy in northern Ghana: a cross-sectional survey
Creators: name: Mackness, Jessica
name: Gallis, John A.
name: Owusu, Raymond Kofi
name: Ali, Mohammed
name: Safiyatu Abubakr-Bibilazu
name: Haliq Adam
name: Aborigo, Raymond
name: Awoonor-Williams, John Koku
name: Lillie, Margaret
name: McEwan, Elena
name: Hembling, John
name: Vasudevan, Lavanya
name: Baumgartner, Joy Noel
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Evaluation of the iMBC/ECD Model on Maternal Mental Health and Child Development in Ghana Baseline survey.
Monte Carlo Radiative Transfer
Creators: name: Whitney, Barbara A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: I outline methods for calculating the solution of Monte Carlo Radiative Transfer (MCRT) in scattering, absorption and emission processes of dust and gas, including polarization. I provide a bibliography of relevant papers on methods with astrophysical applications.
description: To appear in the Chandra Centennial issue of the Bulletin of the Astronomical Society of India, volume 39 (2011), eds D.J. Saikia and Virginia Trimble; 27 pages, 1 figure
title: Potenzial von Serious Games als Instrument zur Beförderung von Nachhaltigkeit
Creators: name: (:Unkn) Unknown
Publisher: name: Umweltbundesamt
Year: 2023
Subjects: subject: Serious Game
subject: Digitalisierung
subject: Gaming
subject: Umweltspiel
subject: Nachhaltigkeit | Strategien | Internationales
subject: Digitalisierung

description: Serious Games haben aufgrund ihres wirkungsgerichteten und zielgruppenspezifischen Charakters großes Potenzial Zielstellungen und Handlungsdimensionen zu nachhaltigerem Handeln zu vermitteln. Der Hintergrundbericht beleuchtet diese Potenziale zum einen auf Basis der allgemeinen Eigenschaften des Mediums (Serious) Game und zeigt dabei beispielsweise auf bei welcher Art Zielstellung die Interaktivität von Games genutzt werden kann. Zum anderen werden konkrete Anwendungsempfehlungen vor dem Hintergrund der Ziele des aktuellen Leitbilds des Umweltbundesamts in der Dimension „Umweltinformation und Dialoge“ präsentiert.
IDENTIFICATION AND CHARACTERIZATION OF THE 'GUT VASCULAR BARRIER'
Creators: name: SPADONI, ILARIA
Publisher: name: Universit� degli Studi di Milano
Year: 2014

description: In order to protect the body from a wide range of harmful environmental agents, the intestine has developed a number of barrier mechanisms to limit the entry of potential hazards. These include the physical barrier formed by the epithelial layer and the intestinal immune system that is important to induce either tolerance against food antigens and intestinal flora or inflammatory responses against dangerous microorganisms. It has been demonstrated that tolerance against commensal bacteria is strictly compartmentalized, in the sense that the systemic immune system is completely unprimed by these bacteria. It was demonstrated that the mLNs function as a ?firewall? confining induction of tolerance to the mucosa while the systemic immune system remains ignorant to these bacteria. However, in these studies how the bacterial flora is excluded from the entrance in the bloodstream via the intestinal blood vessels has not been analyzed. Here, we describe a new barrier that we called the GVB (gut vascular barrier) that plays a fundamental role in controlling the spreading of molecules and bacteria to systemic sites. We found that intestinal endothelial cells (ECs) express the main components of TJs (occludin, JAM-A, CLDN-12, ZO-1 and cingulin) and AJs (VE-cadherin and junctional ?-catenin), indicating the presence of a barrier that excludes bacteria from passing through the paracellular route. In addition, we observed the existence of a ?gut vascular unit? (GVU) whereby ECs were associated with enteric glial cells and pericytes, whose role in the establishment of the endothelial barrier phenotype remains to be analyzed. Moreover, we show that GVB integrity could be modified by Salmonella typhimurium infection. Indeed, upon infection ECs up-regulated the expression of PLVAP, that has been previously used as a marker of immature/damaged vascular barrier in the brain, and up-regulated caveolin-1, the major component of caveolae. These changes correlated with a higher permeability of the endothelium to small molecules and to bacteria. One way by which S. typhimurium could modify the barrier properties of the intestinal blood vessels could be through the negative regulation of the Wnt/?-catenin signaling pathway. Indeed, we found that the activation of ?-catenin was reduced upon Salmonella infection in vitro. Consistently, we found that Salmonella was incapable to modify ECs permeability and to spread systemically in mice where ?-catenin was constitutively activated by genetic means only in vascular ECs. Furthermore, it appeared that the TTSS encoded by Salmonella pathogenicity island-2 was involved in the regulation of Wnt/?-catenin signaling pathway in ECs. Finally, preliminary results show that the microbiota could induce GVB maturation and maintenance. However, the mechanisms involved in these processes as well as the bacterial species responsible for this process have not been investigated yet.
Phunoi Or Côông
Creators: name: Bradley, David (Ed.)
Publisher: name: Pacific Linguistics
Year: 1977

description: PHUNOI or CÔÔNG. 67Abstract 67PREVIOUS WORK 67PHUNOI AND THEIR SETTING 68TRANSCRIPTION: PHONETICS, PHONOLOGICAL INVENTORY 69 1. Minor Syllables 69 2. Initial Consonants 69 3. Vowels 70 4. Final Consonants 70 5. Tones 70PHONOLOGY 70DIALECT DIFFERENCES 72COMPARISON WITH *LOLOISH 73Prefixes 73Initials A. Manner 74Initials B. Position 76 *Tones 77Rhymes 78Vocabulary 81APPENDIX: Counting 94Notes 95Bibliography 96
Additional file 2 of What factors are most important for the development of the maternal–fetal relationship? A prospective study among pregnant women in Danish general practice
Creators: name: Ertmann, Ruth K.
name: Bang, Christine W.
name: Kriegbaum, Margit
name: Væver, Mette S.
name: Kragstrup, Jakob
name: Siersma, Volkert
name: Wilson, Philip
name: Lutterodt, Melissa C.
name: Smith-Nielsen, Johanne
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Developmental Biology
subject: Science Policy

description: Additional file 2. Supplementary file.
Holographic Phase Transition to Topological Dyons
Creators: name: Allahbakhshi, Davood
name: Ardalan, Farhad
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The dynamical stability of a Julia-Zee solution in the AdS background in a four dimensional Einstein-Yang-Mills-Higgs theory is studied. We find that the model with a vanishing scalar field develops a non-zero value for the field at a certain critical temperature which corresponds to a topological dyon in the bulk and a topological phase transition at the boundary.
description: 18 pages, 2 figures, 2 tables, sections 2 and 4 are shortened, an error in the last part of section 5 is corrected and equations are modified. This version to be published in JHEP
IDENTIFICATION OF A SPECIFIC MIRNA PROFILE INHIV EXPOSED SERONEGATIVE INDIVIDUALS
Creators: name: YAHYAEI, SARA
Publisher: name: Universit� degli Studi di Milano
Year: 2015

description: Abstract Objective: MicroRNAs (miRNAs) are small 20- to 24-nt non-coding RNAs involved in the post-transcriptional regulation of gene expression which play important defensive roles in several viral infections. Global expression profiles of cellular miRNAs have identified alterations in the expression of specific miRNA post-HIV-1 infection both in vitro and in different patient cohorts, suggesting a potential role for miRNAs in the pathogenesis and progression of HIV-1 infection. We therefore decided to verify if natural resistance to HIV-1 infection, observed in seronegative individuals repeatedly exposed to HIV-1 (HESN) through unprotected sexual intercourse, could be secondary to a different expression of their miRNA profile. Methods: Expression level of 84 miRNAs was analyzed by RT-PCR array in plasma and unstimulated PBMC of 30 seronegative individuals repeatedly exposed to HIV (HESN), 30 HIV seropositive subjects (HIV+) and 30 healthy controls (HC). Results were confirmed by individual RT-qPCR in plasma, in vitro HIV infected PBMC and supernatants, isolated monocyte and in in vitro HIV infected monocyte derived macrophages (MDM). ABCA1, Dicer and Drosha mRNA expression was analyzed as well. Results: Whereas Dicer and Drosha expression was comparable in HESN, HIV+ and HC, several miRNA were upregulated both in HESN and HIV+ compared to HC, suggesting that exposure to HIV modifies miRNA signature even in the absence of productive infection. MiRNA-29a and miR-223 were upregulated in both unstimulated PBMC and plasma of HESN alone; their expression was reduced upon in vitro HIV infection of HESN PBMC indicating that, upon infection, they are secreted in the extracellular milieu. These results were confirmed by individual qPCR. Additionally, HESN miRNA profile in monocytes clustered with HC one, while, reduced susceptibility to HIV-1 infection in in vitro HIV infected MDM from HESN was associated with higher expression of all our tested miRNAs compared to HCs. Finally, the upregulation of miR-223 in basal PBMC, monocytes and HIV-1 infected MDM resulted into an increased expression of ABCA1. Conclusions: Our studies demonstrate that HIV exposure modifies miRNAs expression. Because those miRNAs that are specifically increased only in HESN have been known to reduce HIV replication via the binding of viral mRNA 3? UTRs, the modulation of these miRNAs could represent an important mechanism in resistance to HIV.
Additional file 1 of Alternative adjustment for seasonality and long-term time-trend in time-series analysis for long-term environmental exposures and disease counts
Creators: name: Honghyok Kim
name: Lee, Jong-Tae
name: Fong, Kelvin C.
name: Bell, Michelle L.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1. Simulation methods and additional results of simulations. Figure S1. Two hypothetical observable lag patterns of the association between 1 μg/m3 increase of exposure to PM10 and mortality, used to generate simulation samples (the last row of panels). A) and B) Hypothetical actual effect (identical). C) Mortality displacement for a few days to several weeks for Observable lag pattern 1. D) Mortality displacement for a few days to several weeks for Observable lag pattern 2. E) Mortality displacement for few days to two years for Observable lag pattern 1. F) Mortality displacement for few days to two years for Observable lag pattern 2. G) Observable lag patterns 1. H) Observable lag pattern 2. Figure S2. An example of simulated samples. A) all-cause death series. B) PM10 series. Table S1. Bias and Standard Deviation for the Association between a Two-Day Moving Average of PM10 (lag0–1) and All-Cause Mortality Estimated by a Model with Different Adjustment Methods for Seasonality and Long-Term Time-Trend over 5000 Samples
UNVEILING SENSORY MECHANISMS FOR THE CONTROL OF TWO INSECT PESTS: FROM BEHAVIOR TO MOLECULAR INTERACTIONS
Creators: name: CATTANEO, ALBERTO MARIA
Publisher: name: Universit� degli Studi di Milano
Year: 2015

description: Pest control strategies targeting insect olfaction represent a promising venue for control of tortricid insects (Lepidoptera: Tortricidae). Among tortricids, the grapevine moth Lobesia botrana (Denis and Schifferm�ller) and the codling moth Cydia pomonella (L.) are serious pests for worldwide production of fruit crops. We employed several approaches to the olfactory system, from electrophysiological and behavioral studies in the grapevine moth, to bioinformatic and molecular studies of olfactory sensory proteins in the codling moth. At the receptor level, we studied both the Olfactory Receptors (ORs), the most common class of sensory proteins mediating detection of odors in insect antennae, and the Transient Receptor Potential (TRP) channels, a novel family of receptor, that recently were also found in the antennae of lepidopterous species. We demonstrated electrophysiological and behavioral responses of the grapevine moth to volatiles emitted by a non-host, Perilla frutescens, previously known to activate TRPs in the rat, Rattus norvegicus. In the codling moth, we characterized a novel TRP channel (TRPA pyrexia-like) and we confirmed activation of its human orthologue to the same non-host compounds active on the olfactory system of the grapevine moth. ORs were heterologously expressed in vivo and in vitro, for identification of their ligands among host and non-host plant volatiles and pheromones (deorphanization). Among several ORs of codling moth, we deorphanized a candidate pheromone receptor (PR) to plant synergists, an OR to non-host volatiles and another PR candidate to a pheromone antagonist of the insect. Our study thus opens for refinement of existing pest control, or novel applications. The behavioral response of the grapevine moth to volatiles from a nonhost plant, and the identification of a novel TRP channel in the codling moth may have perspectives for application in agriculture, targeting the somatosensory system of these tortricids. The evolutionary implications of the responses of the human orthologue of TRPA pyrexia-like to volatiles active on the grapevine moth olfactory system could imply a large degree of conservation of the receptor function. In the codling moth, identification of synergist and antagonist ligands for candidate PRs and deorphanization of an OR to non-host plant volatiles suggest a possible role of these receptors in reproductive and ecological isolation. This could lead to further refinement of existing semiochemicalbased control techniques, by enabling a better understanding of mate- and host-finding in this species.
Additional file 1 of What factors are most important for the development of the maternal–fetal relationship? A prospective study among pregnant women in Danish general practice
Creators: name: Ertmann, Ruth K.
name: Bang, Christine W.
name: Kriegbaum, Margit
name: Væver, Mette S.
name: Kragstrup, Jakob
name: Siersma, Volkert
name: Wilson, Philip
name: Lutterodt, Melissa C.
name: Smith-Nielsen, Johanne
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Developmental Biology
subject: Science Policy

description: Additional file 1: Table 1. Characteristics of the pregnant women.
Higgs production and decay processes via loop diagrams in various 6D Universal Extra Dimension Models at LHC
Creators: name: Nishiwaki, Kenji
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We calculate loop-induced Higgs production and decay processes which are relevant for the LHC in various six-dimensional Universal Extra Dimension models. More concretely, we focus on Higgs production through gluon fusion and Higgs decay into two photons induced by loop diagrams. They are one-loop leading processes and the contribution of Kaluza-Klein particles is considered to be significant. These processes are divergent in six dimensions. Therefore, we employ a momentum cutoff, whose size is fixed from the validity of perturbative calculation through naive dimensional analysis. In these six-dimensional Universal Extra Dimension models, the Higgs production cross section through gluon fusion strongly increases considerably and the Higgs decay width into two photons decrease somehow. In particular in the case of the compactification on Projective Sphere, these effects are remarkable. The deviation of the $h^{(0)} \rightarrow 2 γ$ signal from the prediction of the Standard model is much larger than that in the case of the five-dimensional minimal UED model. We also consider threshold corrections in the two processes and these effect are noteworthy when we choose low cutoff scale in 6D UED. Comparing our calculation to the latest LHC results which were published at the Lepton-Photon 2011 is performed briefly.
description: 31 pages, 27 figures (v1); 38 pages, 16 figures, some discussions and numerical calculations added, some typos fixed, some references added (v2); 46 pages, 16 figures in JHEP format, published version in JHEP, some typos are fixed (v3)
Additional file 2 of Alternative adjustment for seasonality and long-term time-trend in time-series analysis for long-term environmental exposures and disease counts
Creators: name: Honghyok Kim
name: Lee, Jong-Tae
name: Fong, Kelvin C.
name: Bell, Michelle L.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 2. Real data analysis methods and additional results. Table S2. Percentage increase and 95% confidence intervals of cardiovascular mortality risk per a 10 μg/m3 increase in two-day moving average of PM10 (lag0–1) or one-year distributed lags of PM10 (lag0–365) in seven major cities of South Korea, 2006–2013. Table S3. Percentage increase and 95% confidence intervals of respiratory mortality risk per a 10 μg/m3 increase in two-day moving average of PM10 (lag0–1) or one-year distributed lags of PM10 (lag0–365) in seven major cities of South Korea, 2006–2013. Figure S3. Time-series of logarithm of daily all-cause deaths predicted by models with two different adjustments for seasonality and long-term time trend and their absolute differences. A) Time-series in Seoul, 2006–2013 B) Absolute differences in Seoul. C) Time-series in Daegu, 2006–2013. D) Absolute differences in Daegu. Grey vertical dotted lines in B) and D) denote 80th, 90th, and 98th percentile of absolute differences. Figure S4. Results of additional sensitivity analyses in seven major cities of South Korea, 2006–2013. A) All-cause mortality. B) Cardiovascular mortality. C) Respiratory mortality. Percentage increases estimated by models with NCS(doy, 20df)+I(year)+NCS(week, 3df)+NCS(month, 3df) in Table 3 (for all-cause mortality), Table S2 (for cardiovascular mortality), and Table S3 (for respiratory mortality) were duplicated for comparison (red triangles).
Time dependent gamma-ray production in the anisotropic IC $e^\pm$ pair cascade initiated by electrons in active galaxies
Creators: name: Sitarek, J.
name: Bednarek, W.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: New high energy emission features have been recently discovered by the Cherenkov telescopes from active galaxies e.g., a few minutes variability time scale of TeV emission from Mrk 501 and PKS 2155-304, sub-TeV $γ$-ray emission from GeV peaked blazar 3C 279, and TeV emission from two nearby active galaxies, M87 and Cen A, which jets are inclined at a relatively large angle to the line of sight. These results have put a new light on the high energy processes occurring in central parts of active galaxies stimulating more detailed studies of $γ$-ray emission models. Here we report the results of a detailed analysis concerning the most general version of the model for the $γ$-ray production by leptons injected in the jet which interact with the thermal radiation from an accretion disk (the so called {\it external inverse Compton model}). We investigate the $γ$-ray spectra produced in an anisotropic Inverse Compton (IC) $e^\pm$ pair cascade in the whole volume above the accretion disk. The cascade $γ$-ray spectra are obtained for different locations of the observer in respect to the direction of the jet. We also study the time evolution of this $γ$-ray emission caused by the propagation of the relativistic leptons along the jet and the delays resulting from different places of the origin of $γ$-rays above the accretion disk. We discuss the main features of such a cascade model assuming constant injection rate of electrons along the jet. We are investigating two models for their different maximum energies: constant value independent on the distance along the jet or limited by the synchrotron energy losses considered locally in the jet. The model is discussed in the context of blazars observed at small and large inclination angles taking as an example the parameters of the two famous sources Cen A and 3C 279.
description: 16 pages, 18 figures, accepted for publication in MNRAS
Additional file 1 of The association of APOE ε4 with cognitive function over the adult life course and incidence of dementia: 20 years follow-up of the Whitehall II study
Creators: name: Gharbi-Meliani, Amin
name: Dugravot, Aline
name: Sabia, Séverine
name: Regy, Melina
name: Fayosse, Aurore
name: Schnitzler, Alexis
name: Kivimäki, Mika
name: Singh-Manoux, Archana
name: Dumurgier, Julien
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Table S1. Baseline cognitive function as a function of APOE genotype with ε3ε3 as the reference.
Multimodal two and three-photon endomicroscopy for 3D tissue imaging
Creators: name: Liu, Qihao
Publisher: name: University of British Columbia
Year: 2022

description: Multiphoton microscopy (MPM) is a promising multimodal imaging technique that can potentially provide fast, label-free examination of cells, extracellular matrices, and lipids similar to histopathology but without the need for biopsy. Each modality provides a complementary view of biological tissue. For example, two-photon microscopy can detect second harmonic generation from collagen and myosin, whereas two-photon excitation fluorescence can detect intrinsic fluorophores such as NADH from cells. Meanwhile, three-photon microscopy can detect third-harmonic generation from lipid-water and other interfaces. On top of deeper penetration and lower background noise when compared to single-photon microscopy, MPM also has inherent optical sectioning capability. However, the adoption of this non-invasive diagnostic technology by hospitals has been slow because most MPM are bulky, expensive, and complex benchtop systems with solid-state lasers that are not suitable for in vivo operations. To translate the technology to clinical applications, a miniature MPM probe or endoscope is required. Our group has previously developed a fiber-based MPM endoscope with a low-cost femtosecond fiber laser. My contribution was to improve and optimize the performance of this system. A key feature missing in past designs was an axial scanning module to enable automatic acquisition of Z-stacks for volumetric imaging. This was addressed by implementing a shape memory alloy autofocus actuator with accurate scanning over 300 microns. Other areas of improvement that were investigated included resolution, excitation power, and collection efficiency for multimodal imaging. Several objective lenses were compared and lateral resolutions below 1 micron and axial resolutions below 10 microns were achieved for field of view between 100 to 200 microns. Different anti-reflection coatings were explored for the relay lenses to increase the transmission power, most notably for third-harmonic generation. Lastly, the position of the multi-mode fiber was simulated and tested to collect a maximum amount of signal for all three contrasts. Ex-vivo Z-stack imaging experiments on leaf, murine, and piscine samples were conducted to demonstrate multimodality and depth scanning. All these additions and enhancements will serve as a stepping-stone for a prototype that will be clinically tested in the future.
Additional file 3 of The association of APOE ε4 with cognitive function over the adult life course and incidence of dementia: 20 years follow-up of the Whitehall II study
Creators: name: Gharbi-Meliani, Amin
name: Dugravot, Aline
name: Sabia, Séverine
name: Regy, Melina
name: Fayosse, Aurore
name: Schnitzler, Alexis
name: Kivimäki, Mika
name: Singh-Manoux, Archana
name: Dumurgier, Julien
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 3: Table S3. Difference in Standardized Global Cognitive Score between 45 and 85 Years by APOE in 5 Categories.
Theoretisch-practischer Commentar über seines Vaters, Johann Ludwig Schmidts practisches Lehrbuch von gerichtlichen Klagen und Einreden
Creators: name: Schmidt, Ernst Gottfried
Publisher: name: unkn
Year: 2022

description: Theoretisch-practischer Commentar über seines Vaters, Johann Ludwig Schmidts practisches Lehrbuch von gerichtlichen Klagen und Einreden
description: 1
Scale Invariant Avalanches: A Critical Confusion
Creators: name: Ramos, Osvanny
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: The "Self-organized criticality" (SOC), introduced in 1987 by Bak, Tang and Wiesenfeld, was an attempt to explain the 1/f noise, but it rapidly evolved towards a more ambitious scope: explaining scale invariant avalanches. In two decades, phenomena as diverse as earthquakes, granular piles, snow avalanches, solar flares, superconducting vortices, sub-critical fracture, evolution, and even stock market crashes have been reported to evolve through scale invariant avalanches. The theory, based on the key axiom that a critical state is an attractor of the dynamics, presented an exponent close to -1 (in two dimensions) for the power-law distribution of avalanche sizes. However, the majority of real phenomena classified as SOC present smaller exponents, i.e., larger absolute values of negative exponents, a situation that has provoked a lot of confusion in the field of scale invariant avalanches. The main goal of this chapter is to shed light on this issue. The essential role of the exponent value of the power-law distribution of avalanche sizes is discussed. The exponent value controls the ratio of small and large events, the energy balance --required for stationary systems-- and the critical properties of the dynamics. A condition of criticality is introduced. As the exponent value decreases, there is a decrease of the critical properties, and consequently the system becomes, in principle, predictable. Prediction of scale invariant avalanches in both experiments and simulations are presented. Other sources of confusion as the use of logarithmic scales, and the avalanche dynamics in well established critical systems, are also revised; as well as the influence of dissipation and disorder in the "self-organization" of scale invariant dynamics.
description: 32 pages, 17 figures. Reviewed by H. J. Jensen
High performance carbon nanotubes thin film transistors by selective ferric chloride doping
Creators: name: Park, Noh-Hwal
name: Shin, Eun Sol
name: Ryu, Gi-Seong
name: Kwon, Jimin
name: Ji, Dongseob
name: Park, Hyunjin
name: Kim, Yun Ho
name: Noh, Yong-Young
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine

description: Single wall carbon nanotubes (SWNT) have been a significant research topic as active layers for thin film transistors (TFTs) due to their high charge carrier mobility beyond that of crystalline silicon. In this study, we report an effective approach to achieve a very high field-effect mobility and on/off ratio for solution processed semiconducting SWNT TFTs, by selective doping through contact with a thin ferric chloride (FeCl3) dopant layer. The semiconducting layer is formed by a double spin coating of the highly purified (>99%) high pressure carbon mono oxide (HiPCO) SWNT sorted by wrapping of poly (3-dodecylthiophene-2,5-diyl) (P3DDT). In order to achieve effective hole injection from the top Au source electrode without increasing the off-state drain current, less purified (98-99%) SWNTs produced by the plasma discharge process sorted by wrapping of poly (9,9-di-n-dodecylfluorene) (PFDD) are formed on the top of HiPCO film. Significantly improved TFT performance is achieved by the insertion of a few nanometers of a FeCl3 dopant layer at the semiconductor-contact interface. A significant high hole field-effect of 48.35 ± 3.11 cm2V−1s−1 (bare: 6.18 ± 0.87 cm2V−1s−1) with a reasonable on/off current ratio of 105, and low off current of ∼80 pA, are obtained by controlling the concentration of FeCl3 dopant (thickness = 1.5 nm) at the contact. Mobility is improved further at 2.5 nm thickness of the FeCl3 dopant layer resulting in a hole mobility of 177 ± 13.2 cm2 V−1s−1, an on/off ratio of 7.4 × 103, and off state current of 1.2 × 10−9 A.
Additional file 1 of Soot removal from ancient Egyptian complex painted surfaces using a double network gel: empirical tests on the ceiling of the sanctuary of Osiris in the temple of Seti I—Abydos
Creators: name: Al-Emam, Ehab
name: Motawea, Abdel Ghafour
name: Caen, Joost
name: Janssens, Koen
Publisher: name: figshare
Year: 2021
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Additional tables and figures.
Thermal performance prediction of street trees inside isolated open spaces – evaluations from real scale retrofitting project
Creators: name: Zeeshan, Muhammad
name: Ali, Zaib
name: Din, Emad Ud
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences

description: Climate change and the urban heat island (UHI) effects are increasing heat stress and adversely impacting outdoor thermal comfort in urban areas. The study demonstrates that thermal comfort conditions can be improved by reducing air temperature and surface temperature with the integration of street trees into the urban environment. In this work, computational fluid dynamics (CFD) simulations using unsteady Reynolds-averaged Navier–Stokes (URANS) equations have been performed to analyze the cooling effect of street trees for heatwave period (18–22 June 2015) in a hot-humid urban environment. The results are then compared in-term-of air/surface temperature, flow-velocity and apparent temperature for the vegetation case, open-space case, and built case. The analysis shows that the vegetation can effectively decrease surrounding temperature (a reduction of 1.2 K), thereby reducing energy consumption and effectively promote thermal comfort conditions. The study findings will encourage city planners and citizens to take action for urban greening.
Theoretisch-practischer Commentar über seines Vaters, Johann Ludwig Schmidts practisches Lehrbuch von gerichtlichen Klagen und Einreden
Creators: name: Schmidt, Ernst Gottfried
Publisher: name: unkn
Year: 2022

description: Theoretisch-practischer Commentar über seines Vaters, Johann Ludwig Schmidts practisches Lehrbuch von gerichtlichen Klagen und Einreden
description: 2
Additional file 2 of The association of APOE ε4 with cognitive function over the adult life course and incidence of dementia: 20 years follow-up of the Whitehall II study
Creators: name: Gharbi-Meliani, Amin
name: Dugravot, Aline
name: Sabia, Séverine
name: Regy, Melina
name: Fayosse, Aurore
name: Schnitzler, Alexis
name: Kivimäki, Mika
name: Singh-Manoux, Archana
name: Dumurgier, Julien
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2: Table S2. Baseline characteristics of participants as a function of the number of waves of cognitive data over the follow-up.
Yangian Invariant Scattering Amplitudes in Supersymmetric Chern-Simons Theory
Creators: name: Lee, Sangmin
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We propose a generating function for scattering amplitudes of N=6 super-Chern-Simons theory which parallels a recent work on N=4 super-Yang-Mills theory by Arkani-Hamed et al. Our result suggests that the scattering amplitudes of the super-Chern-Simons theory exhibit Yangian invariance.
description: 4 pages; v2. minor corrections; v3. further clarifications and slight change in the title in accordance with the published version
Reentrant phase behaviour for systems with competition between phase separation and self-assembly
Creators: name: Reinhardt, Aleks
name: Williamson, Alexander J.
name: Doye, Jonathan P. K.
name: Carrete, Jesús
name: Varela, Luis M.
name: Louis, Ard A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: In patchy particle systems where there is competition between the self-assembly of finite clusters and liquid-vapour phase separation, reentrant phase behaviour is observed, with the system passing from a monomeric vapour phase to a region of liquid-vapour phase coexistence and then to a vapour phase of clusters as the temperature is decreased at constant density. Here, we present a classical statistical mechanical approach to the determination of the complete phase diagram of such a system. We model the system as a van der Waals fluid, but one where the monomers can assemble into monodisperse clusters that have no attractive interactions with any of the other species. The resulting phase diagrams show a clear region of reentrance. However, for the most physically reasonable parameter values of the model, this behaviour is restricted to a certain range of density, with phase separation still persisting at high densities.
description: 13 pages, 10 figures
Theoretisch-practischer Commentar über seines Vaters, Johann Ludwig Schmidts practisches Lehrbuch von gerichtlichen Klagen und Einreden
Creators: name: Schmidt, Ernst Gottfried
Publisher: name: unkn
Year: 2022

description: Theoretisch-practischer Commentar über seines Vaters, Johann Ludwig Schmidts practisches Lehrbuch von gerichtlichen Klagen und Einreden
description: 3
The development of an agent-based depletion model of Dungeness crab for the evaluation of seasonal management options
Creators: name: Greenberg, Aaron
Publisher: name: University of British Columbia
Year: 2022

description: Dungeness crab (Cancer magister) range from the Aleutian Islands to Central California and grow by moulting in the springtime, entering soft-shell condition after they moult. Unmarketable soft-shell crabs become marketable after a few weeks when their shells harden. Only male crabs larger than 165mm in hard shell can be harvested and sold. This dissertation focuses on the Dungeness crab fishery in the Hecate Strait, British Columbia, between Haida Gwaii and the mainland, and develops fishery models using vessel monitoring system data, within-season harvest control rules, multiple types of biological variation, and seasonal closures. The questions in this dissertation were driven by the central trade-off; having a long fishing season while avoiding setting traps on soft-shell crabs. Four overarching questions related to the central trade-off are as follows: Which factors could most accurately predict weekly crabbing effort when it is of interest to model crab fishery dynamics in the evaluation of in-season crab fishery policy options? What type of population modelling approach is suitable for evaluating in-season fishery policy options for crustaceans where moulting causes the product to be unmarketable for several weeks each year? Which factors drive within season changes in the vulnerability of crustaceans to capture in fisheries, e.g., abiotic factors like sea surface temperature, biological factors like moult condition, or temporal factors like season? Would a management approach which closed and reopened the fishery based on a soft-shell survey lead to better long-term yields and catch rates than fixed date seasonal closures or no seasonal closures? The four main chapters in this thesis examine the Hecate Strait Dungeness crab fishery as a case study. Chapter 2 analyzes fishing effort over the course of the fishing season. Chapters 3 and 4 develop an agent-based depletion model to attempt to estimate various biological quantities. Chapter 5 simulates three alternative management control rules for setting opening and closing dates. This dissertation contributes new methods for evaluating fine timescale commercial catch and trap haul data from vessel monitoring systems and found that setting fishery openings and closures based on a weekly soft shell survey outperformed alternative management control rules.
Theoretisch-practischer Commentar über seines Vaters, Johann Ludwig Schmidts practisches Lehrbuch von gerichtlichen Klagen und Einreden
Creators: name: Schmidt, Ernst Gottfried
Publisher: name: unkn
Year: 2022

description: Theoretisch-practischer Commentar über seines Vaters, Johann Ludwig Schmidts practisches Lehrbuch von gerichtlichen Klagen und Einreden
description: 4
title:  Handling Organization Status Changes in ROR
Creators: name: Krznarich, Elizabeth
Publisher: name: Research Organization Registry (ROR)
Year: 2022
Subjects: classificationCode: 1.2
subject: FOS: Computer and information sciences

description: 2022 was a big year for ROR in many ways, but it was especially notable from a tech standpoint. In early 2022, we built tools and processes that allowed ROR to begin curating the registry separately from GRID, which quickly opened possibilities for tackling projects that had been waiting on the back burner until ROR became fully independent.
Additive Manufacturing of Binary Ni–Ti Shape Memory Alloys Using Electron Beam Powder Bed Fusion: Functional Reversibility Through Minor Alloy Modification and Carbide Formation
Creators: name: Krooß, Philipp
name: Lauhoff, Christian
name: Gustmann, Tobias
name: Gemming, Thomas
name: Sobrero, Céscar E.
name: Ewald, Felix Clemens
name: Brenne, Florian
name: Arold, Tizian
name: Nematollahi, Mohammadreza
name: Elahinia, Mohammad
name: Thielsch, Juliane
name: Hufenbach, Julia Kristin
name: Niendorf, Thomas
Publisher: name: Universität Kassel
Year: 2022
Subjects: subject: shape memory alloy
subject: additive manufacturing
subject: superelasticity
subject: microstructure
subject: 660
subject: Memory-Legierung
subject: Rapid Prototyping
subject: Pseudoelastizität
subject: Mikrostruktur
subject: Schmelzen

description: Gefördert im Rahmen des Projekts DEAL
Theoretisch-practischer Commentar über seines Vaters, Johann Ludwig Schmidts practisches Lehrbuch von gerichtlichen Klagen und Einreden
Creators: name: Schmidt, Ernst Gottfried
Publisher: name: unkn
Year: 2022

description: Theoretisch-practischer Commentar über seines Vaters, Johann Ludwig Schmidts practisches Lehrbuch von gerichtlichen Klagen und Einreden
description: 5
Vertex cover algebras of simplicial multicomplexes
Creators: name: Cimpoeas, Mircea
Publisher: name: arXiv
Year: 2011
Subjects: subject: Commutative Algebra (math.AC)
subject: FOS: Mathematics
subject: 13P10

description: We define vertex cover algebras for weighted simplicial multicomplexes and prove basics properties of them. Also, we describe these algebras for multicomplexes which have only one maximal facet and we prove that they are finitely generated.
description: 4 pages, to appear in Romanian Journal of Mathematics and Computer Science
Additional file 1 of Clinical implementation of PLANET® Dose for dosimetric assessment after [177Lu]Lu-DOTA-TATE: comparison with Dosimetry Toolkit® and OLINDA/EXM® V1.0
Creators: name: Santoro, Lore
name: L. Pitalot
name: D. Trauchessec
name: E. Mora-Ramirez
name: P. O. Kotzki
name: M. Bardiès
name: E. Deshayes
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 1. Table S1: Patients’ characteristics.
Exact results on the quench dynamics of the entanglement entropy in the toric code
Creators: name: Rahmani, Armin
name: Chamon, Claudio
Publisher: name: arXiv
Year: 2010
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study quantum quenches in the two-dimensional Kitaev toric code model and compute exactly the time-dependent entanglement entropy of the non-equilibrium wave-function evolving from a paramagnetic initial state with the toric code Hamiltonian. We find that the area law survives at all times. Adding disorder to the toric code couplings makes the entanglement entropy per unit boundary length saturate to disorder-independent values at long times and in the thermodynamic limit. There are order-one corrections to the area law from the corners in the subsystem boundary but the topological entropy remains zero at all times. We argue that breaking the integrability with a small magnetic field could change the area law to a volume scaling as expected of thermalized states but is not sufficient for forming topological entanglement due to the presence of an excess energy and a finite density of defects.
description: 14 pages, 7 figures, published version
Oksapmin Sentence Structure
Creators: name: Lawrence, Marshall (Ed.)
Publisher: name: Pacific Linguistics
Year: 1972

description: OKSAPMIN SENTENCE STRUCTURE. 17 1. SENTENCE TERMINATION 18 1.1. Information Structure within the Clause 18 1.2. Information Structure and Information Focus within the Sentence 24 2. SENTENCE STRUCTURE 27 2.1. Opening 27 2.1.1. Outer Periphery 27 2.1.2. Inner Periphery 28 2.2. Closure 30 2.2.1. Tense and Mood 30 2.3. Nucleus 33 2.3.1. Simple Nucleus 33 2.3.2. Complex Nucleus 35 2.3.3. Compound Nucleus 38Notes 44