cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Star formation in the outer Galaxy: membership and fundamental parameters of the young open cluster NGC 1893
Creators: name: Prisinzano, L.
name: Sanz-Forcada, J.
name: Micela, G.
name: Caramazza, M.
name: Guarcello, M. G.
name: Sciortino, S.
name: Testi, L.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Different environmental conditions can play a crucial role in determining final products of the star formation process and in this context, less favorable activities of star formation are expected in the external regions of our Galaxy. We studied the properties of the young open cluster NGC 1893 located about 12 Kpc from the galactic center, to investigate how different physical conditions can affect the process of star formation. By adopting a multiwavelength approach, we compiled a catalog extending from X-rays to NIR data to derive the cluster membership. In addition, optical and NIR photometric properties are used to evaluate the cluster parameters. We find 415 diskless candidate members plus 1061 young stellar objects with a circumstellar disk or class II candidate members, 125 of which are also Halpha emitters. Considering the diskless candidate members, we find that the cluster distance is 3.6$\pm$0.2 kpc and the mean interstellar reddening is E(B-V)=0.6$\pm$0.1 with evidence of differential reddening in the whole surveyed region. NGC 1893 contains a conspicuous population of pre-main sequence stars together with the well studied main sequence cluster population; we found a disk fraction of about 70% similar to that found in clusters of similar age in the solar neighbour and then, despite expected unfavorable conditions for star formation, we conclude that very rich young clusters can form also in the outer regions of our Galaxy.
description: 20 pages, 12 PostScript figures. Accepted for publication in Astronomy and Astrophysics
Dynamic and thermodynamic properties of the generalised diamond chain model for azurite
Creators: name: Honecker, Andreas
name: Hu, Shijie
name: Peters, Robert
name: Richter, Johannes
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The natural mineral azurite Cu3(CO3)2(OH)2 is an interesting spin-1/2 quantum antiferromagnet. Recently, a generalised diamond chain model has been established as a good description of the magnetic properties of azurite with parameters placing it in a highly frustrated parameter regime. Here we explore further properties of this model for azurite. First, we determine the inelastic neutron scattering spectrum in the absence of a magnetic field and find good agreement with experiments, thus lending further support to the model. Furthermore, we present numerical data for the magnetocaloric effect and predict that strong cooling should be observed during adiabatic (de)magnetisation of azurite in magnetic fields slightly above 30T. Finally, the presence of a dominant dimer interaction in azurite suggests the use of effective Hamiltonians for an effective low-energy description and we propose that such an approach may be useful to fully account for the three-dimensional coupling geometry.
description: 19 pages, 6 figures; to appear in: J. Phys.: Condens. Matter (special issue on geometrically frustrated magnetism)
Phanoperla imitatrix Zwick
Creators: name: Sivec, Ignac
name: Stark, Bill P.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Plecoptera
Perlidae
Phanoperla
Phanoperla imitatrix

description: Phanoperla imitatrix Zwick Phanoperla imitatrix Zwick, 1986:154. Holotype ♂ (B.P. Bishop Museum). Fyan, Vietnam Material examined. Vietnam: Gia Lai, An Khe Dist., Tram Lap, Azun River, 3 km NE forestry building, 21 June 1996, D. Currie, J. Swann, ROM 961076, 2♂ (ROM). Gia Lai, An Khe Dist., Tram Lap, Azun River, NE Tram Lap, 20 June 1996, B. Hubley, D. Currie, ROM 961073, 1♂ (IEBR). Remarks. Previous records are from the type locality and from the Ban Me Thuot area of Dac Lac Province south of the newly reported sites in Gia Lai Province.
description: Published as part of Sivec, Ignac & Stark, Bill P., 2010, Seven New Species Of Phanoperla Banks From Vietnam And Thailand (Plecoptera: Perlidae), pp. 98-112 in Illiesia 6 (10) on page 102, DOI: 10.5281/zenodo.4759732
description: {"references": ["Zwick, P. 1986. Contribution to the knowledge of Phanoperla Banks, 1938 (Plecoptera: Perlidae). Bulletin de la Societe Entomologique Suisse, 59: 151 - 158."]}
A Note on the Membrane Computer
Creators: name: Adl, Ammar
name: Badr, Amr
name: Farag, Ibrahim
Publisher: name: arXiv
Year: 2010
Subjects: subject: Other Computer Science (cs.OH)
subject: FOS: Computer and information sciences

description: Inspired by the emergent membrane computing (P Systems) concepts, some efforts are carried out introducing simulation models, some are software oriented, and others are hardware, yet all are applied with the current vision of the conventional computers, based on "Von Neumann architecture", which is a sequential design in its essence. We think that these models will need "as a consequent result" to a new architecture exposing a true parallel design, in this paper; we try to investigate and introduce a global view for how it would be like to have such architecture. The main goal is to point out to this direction broadly, suggesting that it might be useful considering some aspects, like the need for a new definition of an operating system and its programs, which will eventually lead to a higher scope: the membrane computer.
Book Review: ”˜Art Therapy and Learning Disabilities – “Don’t guess my happiness”’ Edited by Stephanie Bull and Kevin O’Farrell
Creators: name: Tipple, Robin
Publisher: name: Art Therapy Online
Year: 2015

description: The last book to be published in Britain on Art Therapy with people who have learning disabilities was some time ago, in 1998 – edited by Mair Rees and published by Routledge.
description: Art Therapy Online, Vol 5 No 2 (2014)
Influence of vitamin exposure on Escherichia coli O157:H7 attachment, stress response and virulence
Creators: name: Cancarevic, Ana
Publisher: name: University of British Columbia
Year: 2014

description: Fresh produce is a natural source of vitamins in our diet. Additionally, our enteric flora produces several vitamins, including biotin, cobalamin, folate, menaquinone, pantothenate, and riboflavin. The aim of this study was to determine whether enterically-produced or food-related vitamins may increase attachment of Escherichia coli O157:H7 to leafy green produce, and trigger expression of key stress and virulence genes, thereby enabling its gastrointestinal survival. Late logarithmic phase E. coli O157:H7 grown in M9 minimal medium was exposed to α-tocopherol, ascorbate, biotin, cobalamin, folate, menaquinone, pantothenate, or riboflavin. Following 1.5 and 3 h exposure, HeLa cell assays were performed to assess adherence, while the impact of ascorbic acid, cobalamin and pantothenate on Shiga toxin (Stx) production was quantified by Stx ELISA. Expression of stress response genes (dnaK, osmC, rpoS) was monitored using lux-promoter fusions. Expression of relevant stress response and virulence genes was examined by a quantitative real-time polymerase chain reaction. Lastly, to determine attachment behavior, treated E. coli O157:H7 cells were spotted onto spinach leaves. Treatments with α-tocopherol, biotin, cobalamin, and pantothenate significantly increased adherence to HeLa cells (p<0.05), though only pantothenate (50 mg/mL) produced a >1-log10 increase in adherence. Cobalamin treatment resulted in significantly increased Stx1 and 2 levels (p<0.001), while ascorbate and pantothenate led to lower levels (p<0.001) than the control. In general, exposure to vitamins affected expression of selected virulence and stress response genes. Lastly, vitamin-treated cells attached to the surface of spinach leaves similarly to controls, with the exception of ascorbate and pantothenate treatments where fewer cells attached over a period of 24 h. Increases in E. coli O157:H7 cell concentration on leaves were observed up to 24 h in all treatments, except ascorbate (10 mg/mL) which caused cell numbers to decrease. This study suggests vitamins present in the enteric environment or food have the potential to influence stress response and virulence of E. coli O157:H7, though high concentrations above those found in food or enteric environments are required to elicit these. Ascorbic acid warrants further study as a potentially effective antimicrobial agent for decreasing E. coli O157:H7 contamination on the surface of spinach.
Phanoperla lisu Stark 1983
Creators: name: Sivec, Ignac
name: Stark, Bill P.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Plecoptera
Perlidae
Phanoperla
Phanoperla lisu

description:  Phanoperla lisu Stark Phanoperla lisu Stark, 1983:100. Holotype ♂ (National Reference Collection, Thailand). Chiang Mai, Ban Yang, Thailand Material examined. Thailand: Chiang Mai Province, Doi Suthep-Pui National Park, Namtok Sai Yoi, 98°55’ N, 18° 48’ E, 1000 m, 7 May 2002, 1♂ (PMSL). Remarks. This species was previously known from the holotype (Stark 1983); Uchida &Yamasaki (1989) reported a second specimen from Thung Saleng Luang, Thailand but that is based on a closely related species, P. uchidai which we describe below.
description: Published as part of Sivec, Ignac & Stark, Bill P., 2010, Seven New Species Of Phanoperla Banks From Vietnam And Thailand (Plecoptera: Perlidae), pp. 98-112 in Illiesia 6 (10) on page 103, DOI: 10.5281/zenodo.4759732
description: {"references": ["Stark, B. P. 1983. Descriptions of Neoperlini from Thailand and Malaysia (Plecoptera: Perlidae). Aquatic Insects, 5: 99 - 114.", "Uchida, S. & T. Yamasaki. 1989. Some Perlinae (Plecoptera: Perlidae) from the Malay Peninsula and Thailand with the redescription of Neoperla hamata from Assam. Bulletin of the Biogeographical Society of Japan, 44: 135 - 143."]}
Obituary: Edith Kramer
Creators: name: Dannecker, Karin
Publisher: name: Art Therapy Online
Year: 2015

description: Edith Kramer is widely known not only as a prolific painter but first and foremost as the “mother” of art therapy – a pioneer who formed the thinking and writing in the field and influenced art therapists worldwide. On February 21st 2014 she died at the age of 97 in Grundlsee in the Austrian state of Styria.
description: Art Therapy Online, Vol 5 No 2 (2014)
Editorial
Creators: name: Dalley, Tessa
name: Damarell, Barrie
Publisher: name: Art Therapy Online
Year: 2015

description: The three theoretical papers and an interview with an experienced American art therapist by a leading art therapist from the Czech Republic provide strong international contributions with diverse and different approaches in this issue. Interesting and enlightening, using some rich images, there is a shared theme of self-reflection and, to some extent, self-discovery. Each of the papers explores some aspect of a personal experience and how this contributes to clinical experience and professional understanding. Counter transference response to the dynamics within the therapeutic relationship and the art work made in the sessions forms one of the cornerstones of our work as art therapists. These papers highlight the importance of being open to explore personal responses and experience using the art work and how this adds to the capacity for containment and emotional resonance with our clients and patients.
description: Art Therapy Online, Vol 6 No 1 (2015)
Numerical Analysis of Three-dimensional Acoustic Cloaks and Carpets
Creators: name: Dupont, Guillaume
name: Farhat, Mohamed
name: Diatta, Andre
name: Guenneau, Sebastien
name: Enoch, Stefan
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: Differential Geometry (math.DG)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 78A40, 78A45, 78A48, 78A25, 81V80, 81V65, 82D40, 78M99, 78A50

description: We start by a review of the chronology of mathematical results on the Dirichlet-to-Neumann map which paved the way towards the physics of transformational acoustics. We then rederive the expression for the (anisotropic) density and bulk modulus appearing in the pressure wave equation written in the transformed coordinates. A spherical acoustic cloak consisting of an alternation of homogeneous isotropic concentric layers is further proposed based on the effective medium theory. This cloak is characterised by a low reflection and good efficiency over a large bandwidth for both near and far fields, which approximates the ideal cloak with a inhomogeneous and anisotropic distribution of material parameters. The latter suffers from singular material parameters on its inner surface. This singularity depends upon the sharpness of corners, if the cloak has an irregular boundary, e.g. a polyhedron cloak becomes more and more singular when the number of vertices increases if it is star shaped. We thus analyse the acoustic response of a non-singular spherical cloak designed by blowing up a small ball instead of a point, as proposed in [Kohn, Shen, Vogelius, Weinstein, Inverse Problems 24, 015016, 2008]. The multilayered approximation of this cloak requires less extreme densities (especially for the lowest bound). Finally, we investigate another type of non-singular cloaks, known as invisibility carpets [Li and Pendry, Phys. Rev. Lett. 101, 203901, 2008], which mimic the reflection by a flat ground.
description: Latex, 21 pages, 7 Figures, last version submitted to Wave Motion. OCIS Codes: (000.3860) Mathematical methods in physics; (260.2110) Electromagnetic theory; (160.3918) Metamaterials; (160.1190) Anisotropic optical materials; (350.7420) Waves; (230.1040) Acousto-optical devices; (160.1050) Acousto-optical materials; (290.5839) Scattering,invisibility; (230.3205) Invisibility cloaks
The Others
Creators: name: Gray, Bronwen
Publisher: name: Art Therapy Online
Year: 2015

description: If health is about adaptation, understanding and acceptance, then the arts may be more potent than anything medicine has to offer (Smith, 2002).

What you are about to read is an autoethnographic study of what it was like to work as an art therapist with urban Maori and Pacific Islanders who live on a housing estate in South Auckland. Given that autoethnography is a postmodern research methodology, you will not find neatly defined sections entitled literature review or hypothesis, or a nice neat answer to a question, because this is not how autoethnography works. Autoethnography blends ethnographic interests with life writing and as such is able to bring together an understanding of personal identity and cultural context (Franzosa, 1992). Rather than relying on more conventional approaches to research, the ultimate story has been deconstructed, the literature is woven through the research, assisting with the triangulation of the picture I paint.

It seeks to expand the gambit of what art therapy can include, and in particular when it is practiced at the margins, acting disruptively, which is the ultimate role of any fringe activity. By starting with my lived experience it reflects on the role that dignity has to play in producing optimum health and wellbeing. With a belief that the personal is always political, it seeks to be what Eyreman & Jamison, (1998 p. 22) refer to as both “truth bearing and knowledge producing.” Located within a human rights framework it recognizes that art therapy is not value free or apolitical, it is in fact the exact opposite, and as such, it should demand that we take action about the injustices we uncover.

Set on a housing estate in South Auckland, with a community that most had forgotten about or were afraid of, it is about the places some of us have to call home.

Would you like to come inside?

Keywords: Autoethnography, human rights, Maori, Pacific Islanders, housing estates, rituals
description: Art Therapy Online, Vol 6 No 1 (2015)
Flash Melting Amorphous Ice
Creators: name: Krüger, Constantin Richard
name: Mowry, Nathan Junior
name: Bongiovanni, Gabriele
name: Drabbels, Marcel
name: Lorenz, Ulrich J.
Publisher: name: Zenodo
Year: 2023

description: Here we provide the necessary data and analysis files from the paper "Flash Melting Amorphous Ice"
Group finding in the stellar halo using M-giants in 2MASS: An extended view of the Pisces Overdensity?
Creators: name: Sharma, Sanjib
name: Johnston, Kathryn V
name: Majewski, Steven R.
name: Muñoz, Ricardo R.
name: Carlberg, Joleen K.
name: Bullock, James
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: A density based hierarchical group-finding algorithm is used to identify stellar halo structures in a catalog of M-giants from the Two Micron All Sky Survey (2MASS). The intrinsic brightness of M-giant stars means that this catalog probes deep into the halo where substructures are expected to be abundant and easy to detect. Our analysis reveals 16 structures at high Galactic latitude (greater than 15 degree), of which 10 have been previously identified. Among the six new structures two could plausibly be due to masks applied to the data, one is associated with a strong extinction region and one is probably a part of the Monoceros ring. Another one originates at low latitudes, suggesting some contamination from disk stars, but also shows protrusions extending to high latitudes, implying that it could be a real feature in the stellar halo. The last remaining structure is free from the defects discussed above and hence is very likely a satellite remnant. Although the extinction in the direction of the structure is very low, the structure does match a low temperature feature in the dust maps. While this casts some doubt on its origin, the low temperature feature could plausibly be due to real dust in the structure itself. The angular position and distance of this structure encompass the Pisces overdensity traced by RR Lyraes in Stripe 82 of the Sloan Digital Sky Survey (SDSS). However, the 2MASS M-giants indicate that the structure is much more extended than what is visible with the SDSS, with the point of peak density lying just outside Stripe 82. The morphology of the structure is more like a cloud than a stream and reminiscent of that seen in simulations of satellites disrupting along highly eccentric orbits.
description: Accepted for publication in ApJ
Therapeutic practice: a personal account of an arts based activity
Creators: name: Van Den Akker, José
Publisher: name: Art Therapy Online
Year: 2015

description: From a socio-historical and dynamic systems perspective, family and world environments have meaning to an individual. In art based research with the therapist in mind, the transpersonal practitioner seeks to recognise the complementary nature of cognition and social context, but also the potential of being informed by a larger realm associated with the unmanifest, formless, wordless, the coming into form, into words, hovering between and surrounding seeming separate worlds. This article explores both the process and the outcomes of engaging in an art therapy activity involving the examination of childhood/early adolescence experience and defense mechanisms developed at the time that intensified later in life. The findings may also inspire other art therapy practitioners.

Keywords: therapeutic practice; self-study; arts based activity; interactive field; dialogue
description: Art Therapy Online, Vol 6 No 1 (2015)
Entanglement Witnesses for Graph States: General Theory and Examples
Creators: name: Jungnitsch, Bastian
name: Moroder, Tobias
name: Gühne, Otfried
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a general theory for the construction of witnesses that detect genuine multipartite entanglement in graph states. First, we present explicit witnesses for all graph states of up to six qubits which are better than all criteria so far. Therefore, lower fidelities are required in experiments that aim at the preparation of graph states. Building on these results, we develop analytical methods to construct two different types of entanglement witnesses for general graph states. For many classes of states, these operators exhibit white noise tolerances that converge to one when increasing the number of particles. We illustrate our approach for states such as the linear and the 2D cluster state. Finally, we study an entanglement monotone motivated by our approach for graph states.
description: 12 pages + appendix, 7 figures
Congruence of Professional Values: An Exploration of the Reciprocity between Art Teaching and Art Therapy
Creators: name: Dickson, Clare
Publisher: name: Art Therapy Online
Year: 2015

description: This study explores the overlapping paradigms that exist within the professional disciplines of both art therapy and teaching. The vehicle deployed to articulate these issues is the “Critical Incident Technique” which has been developed as a training tool for teachers. Different approaches to reflective practice, supervision, and experiential learning are explored. In addition the article probes the artistic identity of the art teacher/art therapist and how this impacts on experiential work, in addition to its validity in the teaching arena. This creative identity is omnipresent in both the art teaching and art therapy context and needs to be openly examined. It is argued that different professional values exist particularly in relation to pragmatic issues in art, such as participation, demonstration or collaboration where the creative input of the professional is involved. It concludes that these values can exist in parallel and adapt according to the context and experience. This eclectic approach should be welcomed. These issues are at the core of our professional practice and to encourage debate in the professional arena will lead to more informed practice.

Keywords: teaching, experiential, learning, professional values, critical incident.
description: Art Therapy Online, Vol 6 No 1 (2015)
Interview with Art Therapist Gussie P. Klorer
Creators: name: Šimončičová, Lucia
Publisher: name: Art Therapy Online
Year: 2015

description: I firstly came across Dr. Klorer's work when researching the theme focused on implementation of attachment theory into art therapy practice. I read her chapter called 'Expressive Therapy for Severe Maltreatment and Attachment Disorders: A Neuroscience Framework' that was published in Malchiodi's book 'Creative Interventions with Traumatized Children'. I found her art therapy approach in work with traumatized children and those with attachment difficulties very inspiring. I later translated and published this article in Czech art therapy magazine. I also asked the author, if she would like to share her precious clinical experience with me by participating in my research interviews for my Master's thesis 'Attachment Focused Art Therapy with Adolescent Clients' and that is how the interview was born. It was conducted via a Skype call, on 21 February 2012. Since I was thrilled by the interview outcome, I felt that I do not want to keep it just for myself. I would also like to share it with others who may be interested in attachment focused art therapy practice. I myself edited and abbreviated the original interview in cooperation with the author.
description: Art Therapy Online, Vol 6 No 1 (2015)
La2010: A new orbital solution for the long term motion of the Earth
Creators: name: Laskar, J.
name: Fienga, A.
name: Gastineau, M.
name: Manche, H.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present here a new solution for the astronomical computation of the orbital motion of the Earth spanning from 0 to -250 Myr. The main improvement with respect to the previous numerical solution La2004 (Laskar et al. 2004) is an improved adjustment of the parameters and initial conditions through a fit over 1 Myr to a special version of the high accurate numerical ephemeris INPOP08 (Fienga et al. 2009). The precession equations have also been entirely revised and are no longer averaged over the orbital motion of the Earth and Moon. This new orbital solution is now valid over more than 50 Myr in the past or in the future with proper phases of the eccentricity variations. Due to chaotic behavior, the precision of the solution decreases rapidly beyond this time span, and we discuss the behavior of various solutions beyond 50 Myr. For paleoclimate calibrations, we provide several different solutions that are all compatible with the most precise planetary ephemeris. We have thus reached the time where geological data are now required to discriminate among planetary orbital solutions beyond 50 Myr.
description: 17 pages, 14 figures
The Futile Search for Galactic Disk Dark Matter
Creators: name: Pestaña, José Luis G.
name: Eckhardt, Donald H.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Several approaches have been used to search for dark matter in our galactic disk, but with mixed results: {\em maybe yes and maybe no}. The prevailing approach, integrating the Poisson-Boltzmann equation for tracer stars, has led to more definitive results: {\em yes and no}. The touchstone {\em yes} analysis of Bahcall et al. (1992) has subsequently been confirmed or refuted by various other investigators. This has been our motivation for approaching the search from a different direction: applying the Virial Theorem to extant data. We conclude that the vertical density profile of the disk is not in a state of equilbrium and, therefore, that the Poisson-Boltzmann approach is inappropriate and it thereby leads to indefensible conclusions.
description: Accepted for publication in ApJ Letters
Targeting SARS-CoV-2: A Systematic Drug Repurposing Approach to Identify Promising Inhibitors Against 3C-like Proteinase and 2'-O-RiboseMethyltransferase
Creators: name: Khan, Rameez Jabeer
name: Jha, Rajat Kumar
name: Amera, GizachewMuluneh
name: Jain, Monika
name: Singh, Ekampreet
name: Pathak, Amita
name: Singh, Rashmi Prabha
name: Muthukumaran, Jayaraman
name: Singh, Amit Kumar
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: The recent pandemic associated with SARS-CoV-2, a virus of the Coronaviridae family, has resulted in an unprecedented number of infected people. The highly contagious nature of this virus makes it imperative for us to identify promising inhibitors from pre-existing antiviral drugs. Two druggable targets, namely 3C-like proteinase (3CLpro) and 2'-O-ribose methyltransferase (2'-O-MTase) were selected in this study due to their indispensable nature in the viral life cycle. 3CLpro is a cysteine protease responsible for the proteolysis of replicase polyproteins resulting in the formation of various functional proteins, whereas 2'-O-MTase methylates the ribose 2'-O position of the first and second nucleotide of viral mRNA, which sequesters it from the host immune system. The selected drug target proteins were screened against an in-house library of 123 antiviral drugs. Two promising drug molecules were identified for each protein based on their estimated free energy of binding (ΔG), the orientation of drug molecules in the active site and the interacting residues. The selected protein-drug complexes were then subjected to MD simulation, which consists of various structural parameters to equivalently reflect their physiological state. From the virtual screening results, two drug molecules were selected for each drug target protein [Paritaprevir (ΔG= -9.8 kcal/mol) &Raltegravir (ΔG= -7.8 kcal/mol) for 3CLpro and Dolutegravir (ΔG= -9.4 kcal/mol) and Bictegravir (ΔG= -8.4 kcal/mol) for 2'-OMTase]. After the extensive computational analysis, we proposed that Raltegravir, Paritaprevir, Bictegravir and Dolutegravir are excellent lead candidates for these crucial proteins and they could become potential therapeutic drugs against SARS-CoV-2.
Synthesis, Biological Activity, Molecular Docking Studies of a Novel Series of 3-Aryl-7H-thiazolo[3,2-b]-1,2,4-triazin-7-one Derivatives as the Acetylcholinesterase Inhibitors
Creators: name: Jin, Zhe
name: Zhang, Chao
name: Liu, Miao
name: Jiao, Simeng
name: Zhao, Jing
name: Liu, Xiaoping
name: Lin, Huangquan
name: Wan, David Chi-cheong
name: Hu, Chun
Publisher: name: Taylor & Francis
Year: 2020
Subjects: Biochemistry
Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Hematology
Virology

description: The acetylcholinesterase inhibitors play a critical role in the drug therapy for Alzheimer’s disease. In this study, twenty-nine novel 3-aryl-7H-thiazolo[3,2-b]-1,2,4-triazin-7-one derivatives were synthesized and assayed for their human acetylcholinesterase (hAChE) inhibitory activities. Inhibitory ratio values of seventeen compounds were above 55% with 4c having the highest value as 77.19%. The compounds with the halogen atoms in the aromatic ring, and N,N-diethylamino or N,N-dimethylamino groups in the side chains at C-3 positions exhibited good inhibitory activity. SAR study was carried out by means of molecular docking technique. According to molecular docking results, the common interacting site for all compounds were found to be peripheral anionic site whereas highly active compounds were interacting with the catalytic active site too.
Study of Efimov physics in two nuclear-spin sublevels of 7Li
Creators: name: Gross, Noam
name: Shotan, Zav
name: Machtey, Olga
name: Kokkelmans, Servaas
name: Khaykovich, Lev
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Efimov physics in two nuclear-spin sublevels of bosonic lithium is studied and it is shown that the positions and widths of recombination minima and Efimov resonances are identical for both states within the experimental errors which indicates that the short-range physics is nuclear-spin independent. We also find that the Efimov features are universally related across Feshbach resonances. These results crucially depend on careful mapping between the scattering length and the applied magnetic field which we achieve by characterization of the two broad Feshbach resonances in the different states by means of rf-spectroscopy of weakly bound molecules. By fitting the binding energies numerically with a coupled channels calculation we precisely determine the absolute positions of the Feshbach resonances and the values of the singlet and triplet scattering lengths.
description: 15 pages, 7 figures
Type D Solutions of 3D New Massive Gravity
Creators: name: Ahmedov, Haji
name: Aliev, Alikram N.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In a recent reformulation of three-dimensional new massive gravity (NMG), the field equations of the theory consist of a massive (tensorial) Klein-Gordon type equation with a curvature-squared source term and a constraint equation. Using this framework, we present all algebraic type D solutions of NMG with constant and nonconstant scalar curvatures. For constant scalar curvature, they include homogeneous anisotropic solutions which encompass both solutions originating from topologically massive gravity (TMG), Bianchi types II, VIII, IX, and those of non-TMG origin, Bianchi types VI_{0} and VII_{0} . For a special relation between the cosmological and mass parameters, λ=m^2, they also include conformally flat solutions, and in particular those being locally isometric to the previously-known Kaluza-Klein type AdS_2xS^1 or dS_2x S^1 solutions. For nonconstant scalar curvature, all the solutions are conformally flat and exist only for λ=m^2 . We find two general metrics which possess at least one Killing vector and comprise all such solutions. We also discuss some properties of these solutions, delineating among them black hole type solutions.
description: Dedicated to the memory of Yavuz Nutku; 28 pages, REVTeX
Modelling the Autocovariance of the Power Spectrum of a Solar-Type Oscillator
Creators: name: Campante, T. L.
name: Karoff, C.
name: Chaplin, W. J.
name: Elsworth, Y. P.
name: Handberg, R.
name: Hekker, S.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Asteroseismology is able to conduct studies on the interiors of solar-type stars from the analysis of stellar acoustic spectra. However, such an analysis process often has to rely upon subjective choices made throughout. A recurring problem is to determine whether a signal in the acoustic spectrum originates from a radial or a dipolar oscillation mode. In order to overcome this problem, we present a procedure for modelling and fitting the autocovariance of the power spectrum which can be used to obtain global seismic parameters of solar-type stars, doing so in an automated fashion without the need to make subjective choices. From the set of retrievable global seismic parameters we emphasize the mean small frequency separation and, depending on the intrinsic characteristics of the power spectrum, the mean rotational frequency splitting. Since this procedure is automated, it can serve as a useful tool in the analysis of the more than one thousand solar-type stars expected to be observed as part of the Kepler Asteroseismic Investigation (KAI). We apply the aforementioned procedure to simulations of the Sun. Assuming different apparent magnitudes, we address the issues of how accurately and how precisely we can retrieve the several global seismic parameters were the Sun to be observed as part of the KAI.
description: 10 pages, 8 figures, accepted for publication in MNRAS
Vector bosons escaping from the brane: $e^+e^- \to γ+$ nothing
Creators: name: Astakhov, D. I.
name: Kirpichnikov, D. V.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider phenomenological consequences of RS2-n model with infinite extra dimension, namely, the production, in high energy collisions, of a photon or Z-boson escaping from our brane in association with a photon remaining on the brane. This would show up as process $e^+e^-\rightarrow γ+$nothing. We compare the signal with the Standard Model background coming from $e^+e^- \rightarrow γ\barν ν$. We also make a comparison with $e^+e^-\rightarrow γ+$nothing in the ADD model.
Heljo Heinsalu välipäevik nr 11
Creators: name: Heinsalu, Heljo
Publisher: name: Tallinna Tehnikaülikooli Geoloogia Instituut
Year: 1986
Subjects: Early Ordovician
Tremadoc
Estonia
drill cores
geological descriptions

description: Field notebook with descriptions of Cambrian-Ordovician boundary beds in drill cores of the Rägavere phosphorite field (1986-1987).
VLT Optical BVR observations of two bright Supernova Ia hosts in the Virgo cluster
Creators: name: Cantiello, Michele
name: Biscardi, Ilaria
name: Brocato, Enzo
name: Raimondo, Gabriella
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We study the two galaxies NGC4621 and NGC4374 in the Virgo cluster to derive their distances and stellar population properties. The targets have hosted three type Ia Supernova events allowing to investigate the correlations between the SNeIa and their host stellar systems. Using deep BVR data, obtained with FORS2 at the VLT, we analyse the Surface Brightness Fluctuations (SBF) properties of the targets. We adopt our measurements and existing calibrations to estimate the distance of NGC4621 and NGC4374. For stellar population analysis, we measured SBF amplitudes in different galaxy regions. We present a detailed comparison between data and models to constrain the characteristics of the dominant stellar components at i) various galactic radii, and ii) in the regions where SNeIa were recorded. Our V and R SBF measures provide distances in agreement with literature estimates. The median of our and literature SBF-based distances agrees with the one from non-SBF methods. Comparing data with models we find that stellar populations properties do not change significantly along galactic radius, with a dominant population having old age and solar chemical composition. The galaxies appear similar in all properties analysed, except for B-band SBF. Since the SBF magnitudes in this band are sensitive to the properties of a hot stellar component, we speculate that such behaviour is a consequence of different diffuse hot components in the galaxies. We find that the presence of a percentage of hot-HB stars in old and metal rich stellar populations could be at the origin of the observed differences. We find a good uniformity in the V and R SBF and integrated colours in the regions where the three SNeIa exploded. On the other hand, the B-band SBF signal shows intriguing differences.
description: Accepted for publication on A&A; Abstract shortened
Editorial
Creators: name: Brown, Christopher
name: Tipple, Robin
Publisher: name: Art Therapy Online
Year: 2015

description: Following publication of the Conference Proceedings of the International Art Therapy Conference 2013 in the last issue of ATOL (5,1) we now return to our regular content of peer reviewed articles and other items of interest.
description: Art Therapy Online, Vol 5 No 2 (2014)
Interview with Art therapist Eileen P. McGann
Creators: name: Šimončičová, Lucia
Publisher: name: Art Therapy Online
Year: 2015

description: The first time I came across Eileen McGann was through reading her fascinating article about her art therapy practice with adolescents who had been victims of racism called ”˜Color Me Beautiful: Racism, Identity Formation, and Art Therapy’. I got an opportunity to translate this article and publish it in the Czech Art Therapy magazine Arteterapie. Some time later, we got a chance to meet personally, in Ireland, and discuss her special art therapy approach that focuses on a symbolic visual communication of the therapist with the client, coming from the client’s imagery. In October 2013, I co organized an International Art Therapy Conference in Slovakia ”˜Overall Care of Children in a School Setting’ and we invited Eileen McGann as the main speaker. She introduced her special approach there, which received enthusiastic feedback from people attending the conference.
description: Art Therapy Online, Vol 5 No 2 (2014)
Probabilistic approaches for profiling copy number aberrations and loss of heterozygosity landscapes in cancer genomes
Creators: name: Ha, Gavin
Publisher: name: University of British Columbia
Year: 2015

description: Genomic aberrations such as copy number alterations (CNA) and loss of heterozygosity (LOH) are hallmarks of human malignancies. These genomic abnormalities can have a measurable effect on the structure and dosage of chromosomal regions. Tumour suppressors and oncogenes altered by CNAs often contribute to a tumourigenic phenotype of increased proliferation. CNA and LOH can accrue through the process of branched evolution, resulting in the emergence of divergent clones with distinct aberrations present at diagnosis. Therefore, measuring and modeling how CNA/LOH distribute in cell populations can elucidate the abundance of specific clones and, ultimately, enable the study of clonal evolution. CNA/LOH events in tumours can be profiled using SNP genotyping arrays and whole genome sequencing (WGS). However, to maximize biological interpretability from these data, accurate and statistically robust computational methods for inferring CNA/LOH are necessary. I present three novel probabilistic approaches that apply hidden Markov models (HMM) to analyze CNA/LOH in tumour genomes. The first method is HMM-Dosage, which distinguishes somatic and germline copy number events. This tool was used to profile 2000 breast cancers, the largest study of this kind in the world. The second method is APOLLOH, which was one of the earliest methods developed to profile LOH in tumour WGS data. Its application to WGS of 23 triple negative breast cancers (TNBC) represents the first time that LOH and its effects on allelic expression were jointly analyzed from sequencing data. The third method is TITAN, which simultaneously infers CNA/LOH and the clonal population dynamics from tumour WGS data. This method provides an analytical route to studying the degree of clonal evolution driven by CNA/LOH. I applied TITAN to a novel set of primary breast tumours and corresponding mouse xenografts, presenting the results of distinct modes of temporal clonal selection patterns. In conclusion, this dissertation presents a suite of novel approaches and their application to real-world cancer datasets, contributing to significant discoveries in breast and ovarian cancers. Future applications of these approaches will further facilitate the elucidation of cancer evolution, the genetic basis of metastatic potential, and therapeutic response and resistance.
MAKTABGACHA  TA'LIM TASHKILOTLARIDA MUSIQIY RITMIK HARAKATLARNI TASHKIL ETISH
Creators: name: Karimov, Saxob
name: Tursunboyeva, Marjona
Publisher: name: Zenodo
Year: 2025

description: Ushbu maqolada maktabgacha yoshdagi bolalar uchun musiqiy-ritmik harakatlarning ta’lim va tarbiya jarayonidagi o‘rni tahlil qilinadi. Maqolada musiqiy-ritmik harakatlarni tashkil etish metodlari, pedagogik yondashuvlar va samarali mashg‘ulot o‘tkazish bo‘yicha tavsiyalar keltirilgan.
Finite Element Analysis and Static Loading in Dental Implant with Innovative Crown Design (IN VITRO STUDY)
Creators: name: Dr. Twana Omar Bakr
name: Dr. Fahd S. Ikram
name: Dr. Nabeel S. Martani
Publisher: name: Zenodo
Year: 2023
Subjects: Dental Biomechanics, Dental Implant, Innovative Crown, Zirconia, E-Max, Composite, Implant Length, Finite Element Modeling

description: Abstract
Objective: The purpose of this study is to examine how different crown materials affect stress transformation and distribution around both dental implants. To do this, integrated and combined crowns were built, modelled, and tested under static axial loads using various material combinations. The biomechanical response was then examined. Methods: A validated three‑dimensional finite element (FE) models of crown supported by implant was developed by to evaluate the effect of the different type of material (E max, zirconia, composite) on the short implant. After the FE models had been validated, simulations utilizing various configurations of various crowns fixed to two distinct types of implants were run and subjected to static loading to ascertain the distribution of stresses inside the bone around the implants. Result: The comparative results showed that manufacturing the crown using softer material (i.e., materials with lower elastic modulus) reduced the stress distribution in crown, implant and cancellous bone. It may refer to this phenomenon that softer material can absorb more energy from the applied compressive load, and result in transferring less energy to the implant and jaw bone. However, this effect was not significant on cortical bone compared to the cancellous bone. Combination of different materials for design and manufacturing the crown can alter the biomechanical response and could be beneficial for decreasing the stress distribution in implant and spongy region of jaw bone when stiffer material is needed to be covered in upper surface of the crown. In addition, the results suggests that shorter implant can increase the stress distribution in both cortical and cancellous bone. Conclusion: by using stiff material the stress will increase on the parts of implant and the surrounding bone which may led to failure of implant or bone resorption around of the implant, in other way by using less stiffer material the possibility of success will be increased and also the success rate of the implant is increased, also before deciding which implant size and length are used you select which type of the prosthetic will be used.
USE OF ADVANTAN FOR THE EXTERNAL TREATMENT OF ALLERGIES AND INFLAMMATORY DERMATOSES.
Creators: name: Eshmamatova Ruxshona Tulqin qizi
Publisher: name: Zenodo
Year: 2024

description: Abstract: There are relatively few revolutionary inventions in dermatology that treat some skin diseases at least in magnitude.  The introduction of topical steroids in the complex treatment of inflammatory and allergic dermatoses is exactly what this effect is.

 Key words: Allergy, inflammation, treatment, advantan, dermatosis.

 

Аннотация: В дерматологии относительно немного революционных изобретений, которые лечат некоторые кожные заболевания хотя бы по масштабу. Введение топических стероидов в комплексное лечение воспалительных и аллергических дерматозов — это как раз то, что представляет собой этот эффект.

Ключевые слова: Аллергия, воспаление, лечение, адвантан, дерматоз.
Experimental verification of democratic particle motions by direct imaging of glassy colloidal systems
Creators: name: Fris, J. Ariel Rodriguez
name: Appignanesi, Gustavo A.
name: Weeks, Eric R.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We analyze data from confocal microscopy experiments of a colloidal suspension to validate predictions of rapid sporadic events responsible for structural relaxation in a glassy sample. The trajectories of several thousand colloidal particles are analyzed, confirming the existence of rapid sporadic events responsible for the structural relaxation of significant regions of the sample, and complementing prior observations of dynamical heterogeneity. The emergence of relatively compact clusters of mobility allows the dynamics to transition between the large periods of local confinement within its potential energy surface, in good agreement with the picture envisioned long ago by Adam and Gibbs and Goldstein.
description: 4 pages, 5 figures
Trust the process and press on: Art Therapy and the shared experience of co- editing a film.
Creators: name: Rothwell, Kate
name: Douglas, Emer
Publisher: name: Art Therapy Online
Year: 2015

description: This film was made following a presentation given by Kate Rothwell, Art Psychotherapist, and her long-term private client Peter on 8th December 2012 at the Saturday Forensic Forum (SFF), which is a monthly meeting to discuss psychotherapy with complex patients in difficult settings. For further information see link to website below.
description: Art Therapy Online, Vol 5 No 2 (2014)