cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
การเปรียบเทียบผลของการยับยั้งไวรัสในการรักษาการติดเชื้อเอชไอวีด้วยยาต้านไวรัสระหว่างกลุ่มที่เข้าร่วมรักษาแบบเพื่อนช่วยเพื่อนเทียบกับกลุ่มที่ไม่เข้าร่วมของโรงพยาบาลไชยวาน จังหวัดอุดรธานี
Creators: name: พรชัย คูวิวัฒนชัย
Publisher: name: Division of AIDS&STIs
Year: 2019
Subjects: เอชไอวี
ยาต้านไวรัส
การยับยั้งไวรัส
เพื่อนช่วยเพื่อน
การติดเชื้อเอชไอวี

description: Thai AIDS Journal, 31, 1, 32-39
Additional file 3 of Strategies for the implementation of clinical practice guidelines in public health: an overview of systematic reviews
Creators: name: Pereira, Viviane C.
name: Silva, Sarah N.
name: Carvalho, Viviane K. S.
name: Zanghelini, Fernando
name: Barreto, Jorge O. M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3. Characteristics and AMSTAR2 of the systematic reviews.
NETO, Vítor – O Estado, a Igreja e a sociedade em Portugal (1832-1911). [Lisboa]: Imprensa Nacional – Casa da Moeda, 1998. 619 p.
Creators: name: Abreu, Paulo
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
Factors associated with medication adherence among adults with asthma
Creators: name: Özdemir, Kudret C.
name: Jacobsen, Ramune
name: Dahl, Morten
name: Landt, Eskild
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Asthma medication adherence is of crucial importance for successful disease management. The aim of this study was to identify and rank factors associated with medication adherence among adults with asthma in the general population. We used data on physician-diagnosed asthma, medication adherence, and factors associated with asthma medication adherence from the Danish General Suburban Population Study using a cross-sectional study design. We ranked factors associated with asthma medication adherence based on the magnitude of odds ratios, and the population attributable fractions. Among 20,032 individuals from the general population, 1,128 (6%) suffered from asthma and 822 (73%) of these were adherent to asthma medications. Based on odds ratios, the three top-ranked factors associated with asthma medication adherence were asthma attacks within the past year (4.0; 95% CI: 2.9–5.5), allergy medication use (3.8; 2.6–5.6), and age above median (3.4; 2.4–4.7), followed by asthma severity markers like airway obstruction, and coughing with mucus. Based on population attributable fractions, the three top-ranked factors associated with adherence to asthma medications were asthma attacks within the past year (70%), age above median (57%), and use of allergy medication (49%). The study showed that in the general population recent asthma attacks, higher age, and taking allergy medication were the three most important factors associated with asthma medication adherence. The importance of maintaining adherence to asthma medications even in the absence of severe disease or expressed asthma symptoms should be better communicated to the general population.
Cell-Penetrating Peptides, Electroporation, and Drug Delivery
Creators: name: Cahill, Kevin
Publisher: name: arXiv
Year: 2010
Subjects: subject: Biomolecules (q-bio.BM)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Certain short polycations, such as TAT and oligoarginine, rapidly pass through the plasma membranes of mammalian cells by a mechanism called transduction, as well as by endocytosis and macropinocytosis. These cell-penetrating peptides (CPPs) can carry with them cargos of 30 amino acids, more than the nominal limit of 500 Da and enough to be therapeutic. An analysis of the electrostatics of a charge outside the cell membrane and some recent experiments suggest that transduction may proceed by molecular electroporation. Ways to target diseased cells, rather than all cells, are discussed.
description: 11 pages, 5 figures
Effectiveness and Quality of life in asthmatic patients treated with budesonide/formoterol via Elpenhaler® device in primary care. The “SKIRON” real world study.
Creators: name: Steiropoulos, Paschalis
name: Exarchos, Konstantinos
name: Bertoli, Maria
name: Karakontaki, Foteini
name: Antonogiannakis, Georgios
name: Polychronopoulos, Vlassios
name: Gogali, Athena
name: Kostikas, Konstantinos
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Aim Inhaled corticosteroid (ICS)/long-acting β2 agonist (LABA) combination therapy is used for the effective control of asthma. Aim of this study was to collect data on the effectiveness, safety, quality of life, and patient satisfaction from a fixed dose combination of budesonide/formoterol administered with the Elpenhaler® device following 3-months’ treatment. Methods A 3-month real-life, multicentre, one-arm, prospective observational study (SKIRON study-NCT03055793) was conducted, using the following questionnaires: Asthma Control Questionnaire (ACQ-6) for asthma control assessment, MiniAQLQ questionnaire for QoL assessment, and Feeling of Satisfaction with Inhaler questionnaire (FSI-10) for patients’ satisfaction with the inhaler device. Comorbidities and safety data were also recorded during the study. Results We enrolled 1,174 asthmatic patients following standard clinical practice in primary care from 126 sites in urban and rural areas of Greece. The majority of patients (71.5%) had at least one comorbidity. A statistically significant improvement in the ACQ-6 score was noted at 3 months compared to the baseline evaluation (mean ± SD 2.19 ± 0.97 at baseline vs. 0.55 ± 0.56 at 3 months; mean change -1.64 (95%CI -1.69, -1.57), p < 0.0001). MiniAQLQ score was statistically and clinically significantly improved, compared to baseline, (4.55 ± 1.04 at baseline vs. 6.37 ± 0.64 at 3 months; mean change 1.82 (95%CI 1.75, 1.87), p < 0.0001). The mean FSI-10 score of 44.2 ± 5.4 indicated patient satisfaction and ease-of-use of the Elpenhaler® device. Conclusions In this large real-world study of inadequately-controlled asthma patients in primary care settings, the treatment with budesonide/formoterol FDC with the Elpenhaler® device was associated with significant improvement in patients' asthma control and quality of life.
G20 Government Expenditures Data
Creators: name: Kupfer, Samuel
Publisher: name: Zenodo
Year: 2019

description: Website containing visualizations of data on education, military, and healthcare spending among G20 governments.

To use this site, download the .zip file, unzip it, and use a local webserver to browse the site. It is also available on github.io here.

Created for Visualization of Complex Data (DATS 6401) class at George Washington University. Data originally from World Bank Open Data. This data was preprocessed and transformed for use in this site; preprocessed data available here.
Emergence of Intrinsic Representations of Images by Feedforward and Feedback Processes and Bioluminescent Photons in Early Retinotopic Areas
Creators: name: Bokkon, I.
name: Salari, V.
name: Tuszynski, J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences

description: Recently, we put forwarded a redox molecular hypothesis involving the natural biophysical substrate of visual perception and imagery. Here, we explicitly propose that the feedback and feedforward iterative operation processes can be interpreted in terms of a homunculus looking at the biophysical picture in our brain during visual imagery. We further propose that the brain can use both picture-like and language-like representation processes. In our interpretation, visualization (imagery) is a special kind of representation i.e., visual imagery requires a peculiar inherent biophysical (picture-like) mechanism. We also conjecture that the evolution of higher levels of complexity made the biophysical picture representation of the external visual world possible by controlled redox and bioluminescent nonlinear (iterative) biochemical reactions in the V1 and V2 areas during visual imagery. Our proposal deals only with the primary level of visual representation (i.e. perceived "scene").
description: 18 pages, 4 figures, to be published in Journal of Integrative Neuroscience
ผลการเฝ้าระวังการติดเชื้อเอชไอวี โรคติดต่อทางเพศสัมพันธ์ และพฤติกรรมที่สัมพันธ์กับการติดเชื้อเอชไอวี กลุ่มแรงงานข้ามชาติ ในพื้นที่ 10 จังหวัด ของประเทศไทย ปี พ.ศ. 2553
Creators: name: สหภาพ  พูลเกษร
Publisher: name: Division of AIDS&STIs
Year: 2019
Subjects: การติดเชื้อเอชไอวี
โรคติดต่อทางเพศสัมพันธ์
กลุ่มแรงงานข้ามชาติ

description: Thai AIDS Journal, 31, 2, 55-69
การประเมินรูปแบบการดูแล รักษาผู้ติดเชื้อเอชไอวี/ผู้ป่วยเอดส์ของภาคีเครือข่ายบริการสุขภาพ อำเภอบุณฑริก จังหวัดอุบลราชธานี
Creators: name: วันทนีย์  ธารณธนบูลย์
Publisher: name: Division of AIDS&STIs
Year: 2019
Subjects: ระบบการดูแลรักษาผู้ติดเชื้อเอชไอวี/เอดส์
เอดส์
เอชไอวี

description: Thai AIDS Journal, 31, 2, 70-84
The impact of obesity and uncontrolled asthma during pregnancy on metabolic and inflammatory pathways
Creators: name: Bhaumik, Sreeparna
name: Lockett, Jack
name: Saif, Zarqa
name: Lai, Andrew
name: Salomon, Carlos
name: Whitehead, Jonathan P.
name: Clifton, Vicki L.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Asthma and obesity are both inflammatory complications of pregnancy and when combined contribute to an increased risk of uncontrolled asthma during pregnancy and poor perinatal outcomes. Our previous work has identified the presence of maternal asthma is associated with a proinflammatory milieu in the placenta and reduced fetal growth. The current study was designed to determine the relationships between immunomodulatory metabolic pathways and inflammation and establish whether these pathways are associated with uncontrolled asthma in obese pregnant women. Fifty-three obese (BMI >30) pregnant women were recruited prospectively. Participants were classified as having no asthma, controlled asthma, and uncontrolled asthma based on a doctor diagnosis and assessment using the Asthma Control Questionnaire (ACQ). Circulating plasma concentrations of metabolic hormones leptin, adiponectin, insulin, glucose, and extracellular vesicle (EVs) associated cytokines were measured at 18- and 36-weeks gestation. Concentrations of metabolic and inflammatory markers among obese participants with or without asthma were not significantly different throughout gestation. However total adiponectin concentrations increased as gestation progressed in obese, non-asthmatic women but did not increase in women with asthma. Plasma adiponectin and leptin levels in women with uncontrolled asthma were positively correlated with EV inflammatory markers including GM-CSF, IL-6, TNFα and IFNγ protein. This study demonstrated that most metabolic markers remain unchanged with the presence and severity of asthma in obese pregnant women. However, differences in the associations between metabolic and inflammatory pathways were observed in women with asthma and may be one of the mechanisms contributing to uncontrolled asthma in obese pregnant women.
CLEMENTE, Manuel – Igreja e sociedade portuguesa: do Liberalismo à República. Lisboa: Grifo, 2002. 502 p.
Creators: name: Azevedo, Carlos A. Moreira
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
Small-amplitude capillary-gravity water waves: exact solutions and particle motion beneath such waves
Creators: name: Ionescu-Kruse, Delia
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Two-dimensional periodic surface waves propagating under the combined influence of gravity and surface tension on water of finite depth are considered. Within the framework of small-amplitude waves, we find the exact solutions of the nonlinear differential equation system which describes the particle motion in the considered case, and we describe the possible particle trajectories. The required computations involve elliptic integrals of the first kind, the Legendre normal form and a solvable Abel differential equation of the second kind. Some graphs of the results are included.
RAFAEL, Gina Guedes; SANTOS, Manuela, org. e coord. – Jornais e revistas portugueses do século XIX. Lisboa: Biblioteca Nacional, vol. 1, 1998; vol. 2, 2000
Creators: name: Clemente, Manuel
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
Additional file 4 of Strategies for the implementation of clinical practice guidelines in public health: an overview of systematic reviews
Creators: name: Pereira, Viviane C.
name: Silva, Sarah N.
name: Carvalho, Viviane K. S.
name: Zanghelini, Fernando
name: Barreto, Jorge O. M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 4. Effectiveness of guideline implementation strategies from systematic reviews by type of outcome.
Primary antibody deficiencies represent an underestimated comorbidity in asthma patients: efficacy of immunoglobulin replacement therapy in asthma control
Creators: name: Vivarelli, Emanuele
name: Matucci, Andrea
name: Parronchi, Paola
name: Liotta, Francesco
name: Cosmi, Lorenzo
name: Rossi, Oliviero
name: Cavigli, Edoardo
name: Vultaggio, Alessandra
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Primary antibody deficiencies (PAD) are an underestimated comorbidity in asthma and its treatment could improve disease control. a retrospective cohort of asthmatics, affected by IgG subclass deficiency or unclassified antibody deficiency and treated with low-dose intravenous immunoglobulin replacement therapy (IRT) was recruited. Demographic and clinical data, chest CT scan, blood eosinophils, atopy, chronic oral corticosteroid (OCS) therapy were evaluated at baseline. Asthma exacerbations, lower respiratory tract infections (LRTI), upper respiratory tract infections (URTI) and asthma-related hospitalizations were assessed after one and two years of IRT. 57 moderate-to-severe asthmatics were enrolled, mostly affected by T2 low asthma (39/57, 68.4%). After one year, IRT was effective in improving, irrespective of bronchiectasis, atopy, eosinophils and PAD type: 1) trough IgG (826.9 ± 221.3 vs 942.2 ± 195.1 mg/dl; p < 0.0001) and IgG subclasses (IgG1 355.4 ± 88.4 vs 466.7 ± 122.3, p < 0.0001; IgG2 300.1 ± 130.1 vs 347.6 ± 117.3, p < 0.0005) serum levels. 2) asthma exacerbations (6.4 ± 4.1 vs 2.4 ± 1.9, p < 0.0001), LRTI (4.3 ± 3.9 vs 1.3 ± 1.5, p < 0.0001) and hospitalization rate (0.26 ± 0.7 vs 0.05 ± 0.2, p < 0.01). These results persisted after 2 years of therapy. Estimated mean cumulative OCS exposure was reduced by 4500 mg over the 2-year period. low-dose IRT is effective in improving asthma control and lessening OCS burden in asthmatics affected by PAD.
On one example and one counterexample in counting rational points on graph hypersurfaces
Creators: name: Doryn, Dzmitry
Publisher: name: arXiv
Year: 2010
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: In this paper we present a concrete counterexample to the conjecture of Kontsevich about the polynomial countability of graph hypersurfaces. In contrast to this, we show that the "wheel with spokes" graphs $WS_n$ are polynomially countable.
FEITLER, Bruno – Inquisition, juifs et nouveaux-chrétiens au Brésil: le Nordeste XVIIe et XVIIIe siècles. Leuven: Leuven University Press, 2003. 440 p.
Creators: name: Paiva, José Pedro
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
Platinum(II) and palladium(II) complexes mediated by β-hydroxy-dithioesters ferrocenyl derivatives: synthesis, characterization and antiproliferative activity
Creators: name: Farh, Micheal K.
name: Louzi, Ikrame
name: Abul-Futouh, Hassan
name: Görls, Helmar
name: Häfner, Norman
name: Runnebaum, Ingo B.
name: Weigand, Wolfgang
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Ferrocene and its derivatives compounds have shown a significant role in medicinal organometallic chemistry as an antiparasitic or antibacterial. Therefore, we herein report on the utilization of dithioesters ferrocenyl derivatives as proligands for the synthesis of heteroleptic platinum(II) and homoleptic palladium(II) complexes bearing a conserved O,S binding moiety. The resulting complexes [Pt(L1)(DMSO)Cl] (1), [Pt(L2)(DMSO)Cl] (2), [Pt(L3)(DMSO)Cl] (3), [Pd(L1)2] (4), [Pd(L2)2] (5), and [Pd(L3)2] (6), in which HL1 = methyl 3-hydroxy-3-ferroceneprop-2-enedithioate, HL2 = ethyl 3-hydroxy-3-ferroceneprop-2-enedithioate and HL3 = propyl 3-hydroxy-3-ferroceneprop-2-enedithioate, were fully characterized employing a variety of analytical techniques (NMR spectroscopy, elemental analysis, and mass spectrometry and X-ray structure determination of complexes 2 and 6). Cytotoxicity assays of the synthesized ligands as well as the Pt/Pd metal complexes showed low toxicity towards ovarian cancer cells, but the compounds are not affected by cisplatin resistance mechanisms. Pt(II) complexes exhibited the highest activity, and the alkyl substituent strongly influenced the activity of these complexes and the free ligands. The cytotoxic activity increases with the length of the alkyl chain with 3 exhibiting a mean IC50 of 56 µM.
Effect of heat treatment on the mechanical properties and microstructure of welded abrasion resistant steel AR200
Creators: name: Neykov, Vladimir P.Eng.
Publisher: name: University of British Columbia
Year: 2015

description: Fusion welding process is based on localized melting of materials of similar composition in order to form a permanent joint. Fusion welding is a cost efficient process widely used in the industry to join a variety of materials, weld geometries and weld characteristics. In this research, the effect of heat treatment on the microstructure, mechanical properties and residual stresses of welded abrasion resistant steel AR200 was investigated. Standardized testing as per ASTM regulations has been carried out and included the measurement of the tensile strength, impact strength, hardness and Jominy hardenability on welded and virgin AR200 steel samples. Then, Scanning Electron Microscopy (SEM) and light optical microscopy were carried out to characterize the alloy’s microstructure as a function of heat treatment temperature and time. Finally, residual stress was measured using a neutron diffraction technique, and the elastic residual stress was mapped in the vicinity of welds in AR200 C-sections. The tensile test results revealed a significant variation in the magnitude of yield and ultimate tensile strength between the virgin and heat treated welded AR200 samples, with the welded and heat treated samples exhibiting reduced ductility and strength. SEM microscopy revealed the entrapment of intermetallic compounds originating from weld slag, which acted as stress-concentrations and likely contributed to the initiation of fracture in the tensile specimens. The neutron diffraction results revealed the distribution of residual strain in three orthogonal directions in the virgin AR200 material, heat affected zone and the weld itself. The results suggest that although the heat treatment decreased and homogenized the residual strains, the duration of the heat treatment did not have a significant effect, and thus further optimization of the heat treatment parameters is required. These research findings confirm that successful welding of AR200 abrasion resistant steel must consider both the chemical composition of the steel as well as the heat treatment, part geometry and welding operator technique variability.
Primary estimation with sparsity-promoting bi-convex optimization
Creators: name: Lin, Tim Tai-Yi
Publisher: name: University of British Columbia
Year: 2015

description: This thesis establishes a novel inversion methodology for the surface-related primaries from a given recorded seismic wavefield, called the Robust Estimation of Primaries by Sparse Inversion (Robust EPSI, or REPSI). Surface-related multiples are a major source of coherent noise in seismic data, and inferring fine geological structures from active-source seismic recordings typically first necessitates its removal or mitigation. For this task, current practice calls for data-driven approaches which produce only approximate multiple models that must be non-linearly subtracted from the data, often distorting weak primary events in the process. A recently proposed method called Estimation of Primaries by Sparse Inversion (EPSI) avoids this adaptive subtraction by directly inverting for a discrete representation of the underlying multiple-free subsurface impulse response as a set of band-limited spikes. However, in its original form, the EPSI algorithm exhibits a few notable shortcomings that impede adoption. Although it was shown that the correct impulse response can be obtained through a sparsest solution criteria, the current EPSI algorithm is not designed to take advantage of this finding, but instead approximates a sparse solution in an ad-hoc manner that requires practitioners to decide on a multitude of inversion parameters. The Robust EPSI method introduced in this thesis reformulates the original EPSI problem as a formal bi-convex optimization problem that makes obtaining the sparsest solution an explicit goal, while also reliably admit satisfactory solutions using contemporary self-tuning gradient methods commonly seen in large-scale machine learning communities. I show that the Robust EPSI algorithm is able to operate successfully on a variety of datasets with minimal user input, while also producing a more accurate model of the subsurface impulse response when compared to the original algorithm. Furthermore, this thesis makes several contributions that improves the capability and practicality of EPSI: a novel scattering-based multiple prediction model that allows Robust EPSI to deal with wider near-offset receiver gaps than previously demonstrated for EPSI, as well as a multigrid-inspired continuation strategy that significantly reduces the computation time needed to solve EPSI-type problems. These additions are enabled by and built upon the formalism of the Robust EPSI as developed in this thesis.
BOUZA ÁLVAREZ, Fernando – Comunicación, conoscimiento y memória en la España de los siglos XVI e XVII. Salamanca: Sociedad Española de Historia del Libro; Sociedad de Estudos Medievales y Renascentistas, 1999
Creators: name: Guerreiro, Hugo
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
Iodine-mediated oxidative N–S bond formation: a facile one-pot synthetic approach to 1,2,4-benzothiadiazine 1,1-dioxides under transition metal-free conditions
Creators: name: Uğur, Sümeyye Buran
name: Doğan, Şengül Dilem
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Benzothiadiazine 1,1-dioxide derivatives are widely used because of their diverse biological activities and medicinal prospects. In this study, iodine-oxone mediated oxidative N–S bond formation reaction was described. This new and transition-metal-free approach allows for the convenient synthesis of a variety of 1,2,4-benzothiadiazine 1,1-dioxides from readily available urea derivatives under very mild conditions without using expensive reagents and catalysts. Further, this protocol allows for the development of a library of key building blocks with potential medical applications.
ROSCIONI, Gian Carlo – Il desiderio delle Indie: Storie, sogni e fughe di giovani gesuiti italiani. Torino: Einaudi, 2001. 204 p.
Creators: name: Xavier, Ângela Barreto
name: Palomo, Federico
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
Synthesis of novel adamantane-containing dihydropyrimidines utilizing Biginelli condensation reaction
Creators: name: Aras, Mina Abkar
name: Zonouz, Adeleh Moshtaghi
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences

description: Novel dihydropyrimidines incorporating an adamantane motif have been synthesized using a three-component Biginelli reaction of adamantane-containing β-keto amide N-1-adamantyl acetoacetamide as active methylene compound, thiourea, and aromatic aldehydes in more convenient condition and high yields. The structures of the synthesized compounds were confirmed by spectral data.
Modelling photochemical air pollution from industrial and biogenic emissions in the Terrace-Kitimat valley : a constrained coastal airshed with complex terrain
Creators: name: Weinstein, Benjamin Ralph
Publisher: name: University of British Columbia
Year: 2015

description: This study investigates the worst-case ambient concentrations of O₃ and its precursors (NOx and VOCs) that may occur from the construction of large industrial facilities in the Terrace-Kitimat valley airshed. This research is important as the Terrace-Kitimat valley naturally emits high levels of biogenic VOCs in the summer and many of the proposed facilities will, if constructed, emit high quantities of NOX. To date, literature concerning O₃ production form industrial development in coastal airsheds with complex terrain is sparse. The Comprehensive Air Quality Model with Extensions (CAMx) was used as the photochemical model for this research. Spring and summer periods were selected from 2010. Control and Test Case emission inventories were developed, the former for model evaluation and the latter to assess pollutant change. Model evaluation showed that CAMx was able to emulate daytime O₃ peaks in an adjacent valley for both periods though overnight titration by NO was less adequately replicated. Sensitivity tests revealed that this was due in part to inade- quate Control Case emissions quantification; results improved with the addition of small scale area-based NOx emissions to account for missing sources in the original emissions inventory. Results from the spring period suggest that increased industrial emissions, in general, would not contribute to valley-wide O₃ increases greater than 5 ppb, as biogenic VOC emissions are minimal throughout the airshed during this season. On the other hand, results from the summer period suggest that increased industrial emissions would, at times, contribute to a greater than 55% increase in O₃ concentrations, particularly downwind of Kitimat on days with high temperatures, low planetary boundary layer heights, differential heating of the land and ocean surface temperatures and consecutive days of horizontally recirculating wind. This research also used the modelled O₃ - reactive nitrogen ratio during hours conducive to photochemistry to determine the O₃ sensitivity of the Terrace-Kitimat valley airshed. The airshed is currently sensitive to NOx emissions however the full construction of all proposed industrial projects would likely change the O₃ sensitivity of a large portion of the valley to be sensitive to emissions of VOCs, especially in and around Kitimat.
Additional file 1 of Diagnosis of visceral and cutaneous leishmaniasis using loop-mediated isothermal amplification (LAMP) protocols: a systematic review and meta-analysis
Creators: name: Erber, Astrid Christine
name: Sandler, Peter Julian
name: de Avelar, Daniel Moreira
name: Swoboda, Ines
name: Cota, Gláucia
name: Walochnik, Julia
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 1: Text S1. Search strategy and results per database. Shows the specific search strategy used for the databases included in the review, the search dates and the number of results per database.
Simple Model of the Transduction of Cell-Penetrating Peptides
Creators: name: Cahill, Kevin
Publisher: name: arXiv
Year: 2010
Subjects: subject: Biomolecules (q-bio.BM)
subject: FOS: Biological sciences

description: Cell-penetrating peptides (CPPs) such as HIV's trans-activating transcriptional activator (TAT) and polyarginine rapidly pass through the plasma membranes of mammalian cells by an unknown mechanism called transduction. They may be medically useful when fused to well-chosen chains of fewer than about 35 amino acids. I offer a simple model of transduction in which phosphatidylserines and CPPs effectively form two plates of a capacitor with a voltage sufficient to cause the formation of transient pores (electroporation). The model is consistent with experimental data on the transduction of oligoarginine into mouse C2-C12 myoblasts and makes three testable predictions.
description: Seven pages. For a more complete version including the effects of counterions, see arXiv:0810.2358v3 [q-bio.BM]
MARTINS, Maria Odete Soares – A Missionação nas Molucas no século XVI: Contributo para o estudo da acção dos Jesuítas no Oriente. Lisboa: Centro de História de Além-Mar da Universidade Nova de Lisboa, 2002. Colecção Teses, 2. 317 p.
Creators: name: Ptak, Roderich
name: Chaves, João
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
BRAGA, Isabel M. R. Mendes Drumond – Mouriscos e cristãos no Portugal quinhentista: duas culturas e duas concepções religiosas em choque. Lisboa: Hugin Editores, 1999. 180 p.
Creators: name: Lavajo, Joaquim Chorão
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
FONTOURA, Otília Rodrigues, OSC. – As Clarissas na Madeira: uma presença de 500 anos. Funchal: Centro de Estudos de História do Atlântico; Secretaria Regional do Turismo e Cultura, 2000. 579 p.
Creators: name: Andrade, Maria Filomena
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
The symbiotic system Z Andromedae : a spectral analysis of the anomalous 1984-1986 outburst
Creators: name: Contini, M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The visual magnitude profile of the symbiotic system Z And during the 1984-1986 activity period appears double peaked and the flux intensity is low compared to outbursts in other epochs. The detailed modeling of the observed spectra, accounting for the shells ejected by the red giant star, shows that the outburst is intrinsically single but distorted by the collision at different phases of the white dwarf wind with two close shells.
description: 16 pages, 3 figs., accepted for publication in New Astr
PIXEL 2010 - a Resume
Creators: name: Wermes, Norbert
Publisher: name: arXiv
Year: 2010
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The Pixel 2010 conference focused on semiconductor pixel detectors for particle tracking/vertexing as well as for imaging, in particular for synchrotron light sources and XFELs. The big LHC hybrid pixel detectors have impressively started showing their capabilities. X-ray imaging detectors, also using the hybrid pixel technology, have greatly advanced the experimental possibilities for diiffraction experiments. Monolithic or semi-monolithic devices like CMOS active pixels and DEPFET pixels have now reached a state such that complete vertex detectors for RHIC and superKEKB are being built with these technologies. Finally, new advances towards fully monolithic active pixel detectors, featuring full CMOS electronics merged with efficient signal charge collection, exploiting standard CMOS technologies, SOI and/or 3D integration, show the path for the future. This résumé attempts to extract the main statements of the results and developments presented at this conference.
description: 8 pages, 19 figures, conference summary
Additional file 3 of Diagnosis of visceral and cutaneous leishmaniasis using loop-mediated isothermal amplification (LAMP) protocols: a systematic review and meta-analysis
Creators: name: Erber, Astrid Christine
name: Sandler, Peter Julian
name: de Avelar, Daniel Moreira
name: Swoboda, Ines
name: Cota, Gláucia
name: Walochnik, Julia
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 3: Table S2. Main methodological characteristics of studies addressing the diagnosis of leishmaniasis in humans.
Synthesis, spectroscopic characterization, biological activity, and conducting properties of functionalized Ni(II) dithiocarbamate complexes with solvent extraction studies of the ligands
Creators: name: Maurya, Vinay Kumar
name: Prasad, Lal Bahadur
name: Singh, Anupam
name: Shiv, Kunal
name: Prasad, Akhilesh
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: A series of new nickel(II) dithiocarbamate complexes of general formula [M L2], (where L = benzyl(4-fluorobenzyl)carbamodithioate (L1), benzyl(4-cyanobenzyl)carbamodithioate (L2), ethyl(4-methylbenzyl)carbamodithioate (L3), (4-methoxybenzyl) (naphthalen-1-ylmethyl)carbamodithioate (L4) and ethyl(4-methoxybenzyl)carbamodithioate (L5)) have been synthesized, and characterized via elemental analysis, FT-IR, electronic spectra, 1H NMR, 13C NMR, Mass spectrometry and Thermogravimetric analysis (TGA). The continuous variation method (Job's method) was used to determine the stoichiometry of the complexes. TGA was used to analyze the thermal decomposition behavior of metal complexes in nitrogen atmosphere. As a result of the thermal decomposition process, all of the complexes produced NiS as the final product. X-ray Diffraction (XRD), Energy dispersive X-ray analysis (EDAX), and Transmission electron microscopy (TEM) studies confirm the formation of NiS nanomaterial. Crystalline size of NiS was obtained between 19.97 to 21.35 nm range by applying the Scherrer equation using XRD. Solid-state electrical conductivities reveal that all the complexes behave as a semiconductor at room temperature. All the synthesized dithiocarbamate ligands and complexes were screened against five human bacterial pathogens (Escherichia coli, Staphylococcus aureus, Salmonella typhi, Aeromonas hydrophila, and Shigella boydii) by disc diffusion method. Solvent extraction studies show that the ligand has strong extractability towards metal ions in a basic medium (pH = 10).
VELASCO BAYÓN, Balbino, O. Carm. – História da Ordem do Carmo em Portugal. Lisboa: Paulinas, 2001. 755 p. [28 p. il.]
Creators: name: Santos, Maria Leonor Ferraz De Oliveira Silva
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
Additional file 4 of Diagnosis of visceral and cutaneous leishmaniasis using loop-mediated isothermal amplification (LAMP) protocols: a systematic review and meta-analysis
Creators: name: Erber, Astrid Christine
name: Sandler, Peter Julian
name: de Avelar, Daniel Moreira
name: Swoboda, Ines
name: Cota, Gláucia
name: Walochnik, Julia
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 4: Figure S1. QUADAS-2 based quality risk assessment.
DICIONÁRIO de História Religiosa de Portugal. Dir. de Carlos Moreira Azevedo. Lisboa: Círculo de Leitores, 2000-2001. 4 vols.
Creators: name: Matos, Sérgio Campos
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna
Metal complexes of new thiocarbohydrazones of Cu(I), Co(II), and Ni(II); identification by NMR, IR, mass, UV spectra, and DFT calculations
Creators: name: Aly, Ashraf A.
name: Abdallah, Elham M.
name: Ahmed, Salwa A.
name: Awad, Mohamed K.
name: Rabee, Mai M.
name: Mostafa, Sara M.
name: Bräse, Stefan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: Cancer

description: Substituted thiocarbohydrazones were synthesized to study their complexation capability towards Cu(I), Co(II), and Ni(II) salts. The Cu(I) complexes showed ligation of one mole of Cu(I)Br to one of the synthesized ligands to form a cationic–anionic metal complex. Co(II) and Ni(II) complexes were determined due to the chelating of equal equivalents of both ligands and metal salts to form monodentate metal dihalogenated complexes. Metal complexes were characterized by mass spectrometry, IR, NMR, UV spectra, and elemental analyses. Theoretical calculations were performed using density functional theory (DFT) at the B3LYP level with 6–31 + G(d) and LANL2DZ basis sets to access reliable results to the experimental values. The calculations were performed to obtain the optimized molecular geometry, charge density distribution, extent of distortion from regular geometry, the HOMO (highest occupied molecular orbital), the LUMO (lowest unoccupied molecular orbital), the molecular electrostatic potential (MEP), reactivity index (ΔE), dipole moment (D), global hardness (η), softness (σ), electrophilicity index (ω), and chemical potential. The calculations confirmed that the investigated complexes have a reliable geometry, agreeing with the experimental observation.
Canadian clarinet music as multicultural action
Creators: name: Earle, Shawn Hubert
Publisher: name: University of British Columbia
Year: 2015

description: Despite the wealth of Canadian clarinet repertoire, most of the existing studies focus only on pedagogy for student performers. Its significance and merit can better be understood, however, by considering its cultural context, especially through the perspective of Canadian identity. Canada’s social framework directly impacts its musical output and reflects Canada’s core values, especially multiculturalism, which became government policy in 1971. Using multiculturalism as a focal point for examining Canadian clarinet repertoire, this study explores the ways in which music performance is a multicultural action rather than simply stating the fact of social pluralism. From a list of Canadian clarinet works reflecting multiculturalism, selected works have been chosen for detailed study. Empty Sky by Elliot Weisgarber, Sitpatsimoyi by Robert Rosen, Anerca II by Milton Barnes, and Between the Shore and the Ships by Derek Charke are four Canadian works which use the clarinet as a solo instrument and reflect the ethnocultural groups the Canadian Multiculturalism Act accommodates: immigrants, First Nations, and French-speaking people. Selected works are examined from contextual and musical perspectives for representations of ethnocultural identity. Likewise, performance decisions are discussed revealing how performance is a multicultural gesture requiring musical, contextual, and social analysis. The evaluation of these factors are consolidated into performance which musically illustrates an understanding and sensitivity to ethnocultural accommodation and comments on social issues making each performance a multicultural action.
Peakons arising as particle paths beneath small-amplitude water waves
Creators: name: Ionescu-Kruse, Delia
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We present a new kind of particle path in constant vorticity water of finite depth, within the framework of small-amplitude waves.
Property and reactivity of polyselenides and polysulfides: a quantum chemistry study
Creators: name: Pi, Hui-Chu
name: Hu, Ching-Han
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: High-level ab initio and density functional theory were applied to investigate property and reactivity of polyselenides and polysulfides. With CH3XnH (X = S or Se) we found that the deprotonation energy (and pKa) of CH3SenH, ionization potential (IP) of , and CH3Sen−H bond dissociation energy (BDE) are lower than those of their sulfur counterparts. For n = 2, IPs and X−H BDEs are exceptionally small. The relative nucleophilicity of CH3Xn− vary with substrates. However, CH3SenH are more nucleophilic than CH3SnH due to their due to their lower deprotonation energy. The nucleophilicity of selenolates versus thiolates are related to the chemical nature. Selenium is more electrophilic than sulfur.
title: Αναμόρφωση γραμμικών διαδικασιών σε μηχανουργικές κατεργασίες με την εφαρμογή των αρχών της Κυκλικής οικονομίας
title: Reforming linear processes in machining using the principles of Circular economy
Creators: name: Κοντογιαννη Ιωαννα
Publisher: name: Technical University of Crete
Year: 2021

description: Η εργασία αρχικά αυτή θα αναπτύξει τη σημερινή έννοια της κυκλικής οικονομίας, τα κύρια χαρακτηριστικά της με παρουσίαση παραδειγμάτων και εφαρμογών στον
κατασκευαστικό κλάδο. Θα πραγματοποιηθεί ανασκόπηση και ανάλυση των εφαρμογών κυκλικής οικονομίας σε τομείς παραγωγής. Θα παρουσιαστεί ένα γενικό πλάνο - σχέδιο για μια κατασκευαστική εταιρεία, τα χαρακτηριστικά της και σε ποιά στάδια θα μπορούσε να εφαρμόσει ένα τέτοιο σύστημα.
description: This thesis will introduce the  concept circular economy, namely examples and applications in an industrial scale. Their implementation will be  reviewed and analyzed in detail. Furthermore, an outlined plan will be  presented  for an integration of such policies.
Introduction to flavor physics
Creators: name: Grossman, Yuval
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: This set of lectures covers the very basics of flavor physics and are aimed to be an entry point to the subject. A lot of problems are provided in the hope of making the manuscript a self study guide.
description: 45 pages. Lectures given at the "2009 European School of High-Energy Physics," Bautzen, Germany, June 14-27, 2009, and at the "Flavianet School on Flavor Physics," Karlsruhe, Germany, September 7-18, 2009
Indigitalized : traditional Métis artistic expression in contemporary media art
Creators: name: Corbett, Jon Michael Robert
Publisher: name: University of British Columbia
Year: 2015

description: This thesis examines a re-indigenizing process facilitated through traditional and computer-based media artistic expressive forms. My recent discovery of my Canadian Indigenous ancestry has brought me to investigate how my identity as a contemporary artist has been impacted by my exploration of Indigenous forms of expression that were lost to me due to my grandmother’s assimilation to a homogenized Canadian ideal. I examined the relationships between my contemporary artistic practice and Indigenous perspectives to develop an exhibition of work that bridged computer-based media and traditional Métis beading practice. My artistic influences and a descriptive account of my current artistic practices is synthesised with my new Indigenous knowledge of identity and expression, which not only produced several works of art, but also generated new programmatic methodologies and a computer-based media toolkit that can aid Indigenous artists with developing computer and media based art projects.
HISTÓRIA Religiosa de Portugal. Dir. de Carlos Moreira Azevedo. Vol. 3: Religião e Secularização. Coord. de Manuel Clemente; António Matos Ferreira. Lisboa, Círculo de Leitores, 2002, 584 p.
Creators: name: Ribeiro, Maria Manuela Tavares
Publisher: name: Lusitania Sacra
Year: 2003

description: Lusitania Sacra, n. 15 (2003): Poder, Sociedade e Religião na Época Moderna