title: ÐÐ»Ð¸ÑÐ½Ð¸Ðµ Ð²Ð¸ÑÑÑÐ° Ð»ÐµÐ¹ÐºÐ¾Ð·Ð° ÐºÑÑÐ¿Ð½Ð¾Ð³Ð¾ ÑÐ¾Ð³Ð°ÑÐ¾Ð³Ð¾ ÑÐºÐ¾ÑÐ° Ð½Ð° ÐºÐ°ÑÐµÑÑÐ²Ð¾ Ð¼Ð¾Ð»Ð¾ÑÐ½Ð¾Ð¹ Ð¿ÑÐ¾Ð´ÑÐºÑÐ¸Ð¸ Ð¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð¼ Ð¿Ð¾ÑÑÐµÐ±Ð¸ÑÐµÐ»Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: The influence of bovine leukemia virus on the quality of milk products and the consumer's body
Creators: name: ÐÐ°ÑÐºÐ°Ð²Ð°Ñ, ÐÐµÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2022
Subjects: ÐÐ¸Ð¾ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ñ
ÐÐ¸ÑÑÑÐ¾Ð»Ð¾Ð³Ð¸Ñ
Ð»ÐµÐ¹ÐºÐ¾Ð·
Ð¼Ð¾Ð»Ð¾ÐºÐ¾
Ð¼Ð¾Ð»Ð¾ÑÐ½Ð°Ñ Ð¿ÑÐ¾Ð´ÑÐºÑÐ¸Ñ
ÐºÐ¾ÑÐ¾Ð²Ñ
ÐºÐ°ÑÐµÑÑÐ²Ð¾
Ð²Ð¸ÑÑÑ Ð»ÐµÐ¹ÐºÐ¾Ð·Ð° ÐºÑÑÐ¿Ð½Ð¾Ð³Ð¾ ÑÐ¾Ð³Ð°ÑÐ¾Ð³Ð¾ ÑÐºÐ¾ÑÐ°
Ð¸Ð½Ð±ÑÐµÐ´Ð½ÑÐµ Ð¼ÑÑÐ¸ Balb/c
Ð¼ÐµÑÐ°Ð±Ð¾Ð»Ð¸ÑÑ
leukemia
milk
milk products
cows
quality
bovine leukemia virus
Balb/c inbred mice
metabolites

description: Ð¢ÐµÐ¼Ð° Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ: Â«ÐÐ»Ð¸ÑÐ½Ð¸Ðµ Ð²Ð¸ÑÑÑÐ° Ð»ÐµÐ¹ÐºÐ¾Ð·Ð° ÐºÑÑÐ¿Ð½Ð¾Ð³Ð¾ ÑÐ¾Ð³Ð°ÑÐ¾Ð³Ð¾ ÑÐºÐ¾ÑÐ° Ð½Ð° ÐºÐ°ÑÐµÑÑÐ²Ð¾ Ð¼Ð¾Ð»Ð¾ÑÐ½Ð¾Ð¹ Ð¿ÑÐ¾Ð´ÑÐºÑÐ¸Ð¸ Ð¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð¼ Ð¿Ð¾ÑÑÐµÐ±Ð¸ÑÐµÐ»ÑÂ». Ð Ð°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð½Ð°ÑÑÐ½Ð¾-ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¼Ñ Ð¸Ð·ÑÑÐµÐ½Ð¸Ñ ÐºÐ°ÑÐµÑÑÐ²Ð° Ð¼Ð¾Ð»Ð¾ÐºÐ° Ð² Ð·Ð°Ð²Ð¸ÑÐ¸Ð¼Ð¾ÑÑÐ¸ Ð¾Ñ Ð¸Ð½ÑÐ¸ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾ÑÑÐ¸ ÐºÐ¾ÑÐ¾Ð² Ð²Ð¸ÑÑÑÐ¾Ð¼ Ð»ÐµÐ¹ÐºÐ¾Ð·Ð° ÐºÑÑÐ¿Ð½Ð¾Ð³Ð¾ ÑÐ¾Ð³Ð°ÑÐ¾Ð³Ð¾ ÑÐºÐ¾ÑÐ° Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð»Ð¸ÑÐµÑÐ°ÑÑÑÐ½ÑÑ Ð´Ð°Ð½Ð½ÑÑ Ð¸ Ð½Ð°ÑÑÐ½Ð¾-Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¾Ð¼Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¾Ð»Ð¸ ÑÐ°ÐºÐ¾Ð³Ð¾ Ð¼Ð¾Ð»Ð¾ÐºÐ° Ð² Ð¾Ð½ÐºÐ¾Ð³ÐµÐ½ÐµÐ·Ðµ Ð¸Ð½Ð±ÑÐµÐ´Ð½Ð¾Ð¹ Ð»Ð¸Ð½Ð¸Ð¸ Ð±ÐµÐ»ÑÑ Ð¼ÑÑÐµÐ¹ BALB/c Ñ Ð¿ÐµÑÐµÐ²Ð¸Ð²Ð°ÐµÐ¼Ð¾Ð¹ Ð»Ð¸Ð½Ð¸ÐµÐ¹ Ð¿Ð»Ð°Ð·Ð¼Ð°ÑÐ¸ÑÐ¾Ð¼Ð½ÑÑ (Ð¼Ð¸ÐµÐ»Ð¾Ð¼Ð½ÑÑ) ÐºÐ»ÐµÑÐ¾Ðº Sp.2/0 â Ag.8. Ð­ÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ°Ð»ÑÐ½Ð°Ñ ÑÐ°ÑÑÑ Ð½Ð°ÑÑÐ½Ð¾-Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°ÑÐµÐ»ÑÑÐºÐ¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° Ð½Ð° Ð±Ð°Ð·Ðµ Â«ÐÐÐ ÐÐÐÐÐÐÐ-ÐÐ ÐÂ» Ð¸ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð° Ð² ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²Ð¸Ð¸ Ð¿Ð¾ÑÑÐ°Ð²Ð»ÐµÐ½Ð½ÑÐ¼Ð¸ Ð·Ð°Ð´Ð°ÑÐ°Ð¼Ð¸: Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð»ÑÑ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐ¿Ð¸Ð·Ð¾Ð¾ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¸ÑÑÐ°ÑÐ¸Ñ Ð² Ð´Ð²ÑÑ ÑÐ¾Ð·ÑÐ¹ÑÑÐ²Ð°Ñ, Ð½ÐµÐ±Ð»Ð°Ð³Ð¾Ð¿Ð¾Ð»ÑÑÐ½ÑÑ Ð¿Ð¾ Ð»ÐµÐ¹ÐºÐ¾Ð·Ñ ÐºÑÑÐ¿Ð½Ð¾Ð³Ð¾ ÑÐ¾Ð³Ð°ÑÐ¾Ð³Ð¾ ÑÐºÐ¾ÑÐ°; Ð±ÑÐ»Ð¾ Ð¿ÑÐ¸Ð²ÐµÐ´ÐµÐ½Ð¾ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÐµÐ¹ ÐºÐ°ÑÐµÑÑÐ²Ð° Ð¼Ð¾Ð»Ð¾ÐºÐ° Ð¾Ñ ÑÐµÑÐ¾Ð½ÐµÐ³Ð°ÑÐ¸Ð²Ð½ÑÑ Ð¸ ÑÐµÑÐ¾Ð¿Ð¾Ð·Ð¸ÑÐ¸Ð²Ð½ÑÑ ÐºÐ¾ÑÐ¾Ð² Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð»Ð¸ÑÐµÑÐ°ÑÑÑÐ½ÑÑ Ð´Ð°Ð½Ð½ÑÑ; Ð²Ð¾ÑÐ¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ð° ÑÐ¾Ð»Ð¸Ð´Ð½Ð°Ñ Ð¾Ð¿ÑÑÐ¾Ð»Ñ Ð½Ð° Ð¼ÑÑÐ°Ñ Ð»Ð¸Ð½Ð¸Ð¸ Balb/c Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸ÐµÐ¼ ÑÐ¸Ð½Ð³ÐµÐ½Ð½Ð¾Ð¹ Ð¿Ð»Ð°Ð·Ð¼Ð¾ÑÐ¸ÑÐ¾Ð¼Ð½Ð¾Ð¹ (Ð¼Ð¸ÐµÐ»Ð¾Ð¼Ð½Ð¾Ð¹) Ð»Ð¸Ð½Ð¸Ð¸ ÐºÐ»ÐµÑÐ¾Ðº Sp.2/0 â Ag.8; Ð¸Ð·ÑÑÐµÐ½Ð¾ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ðµ Ð¾Ð¿ÑÑÐ¾Ð»Ð¸ Ð² Ð·Ð°Ð²Ð¸ÑÐ¸Ð¼Ð¾ÑÑÐ¸ Ð¾Ñ Ð²Ð²Ð¾Ð´Ð¸Ð¼Ð¾Ð¹ Ð´Ð¾Ð·Ñ Ð¼Ð¸ÐµÐ»Ð¾Ð¼Ð½ÑÑ ÐºÐ»ÐµÑÐ¾Ðº; Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¾ Ð²Ð»Ð¸ÑÐ½Ð¸Ðµ Ð²Ð²Ð¾Ð´Ð¸Ð¼Ð¾Ð³Ð¾ Ð² ÑÐ°ÑÐ¸Ð¾Ð½ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÑ Ð¼Ð¾Ð»Ð¾ÐºÐ° Ð¾Ñ Ð ÐÐ-Ð¿Ð¾Ð»Ð¾Ð¶Ð¸ÑÐµÐ»ÑÐ½ÑÑ ÐºÐ¾ÑÐ¾Ð² ÑÐ°Ð·Ð½Ð¾Ð¹ Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð½Ð° ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ðµ Ð¾Ð¿ÑÑÐ¾Ð»Ð¸ Ñ ÑÐ°Ð¼ÑÐ¾Ð² Ð¸ ÑÐ°Ð¼Ð¾Ðº Ð¼ÑÑÐµÐ¹ Ð»Ð¸Ð½Ð¸Ð¸ Balb/c. Ð ÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð½Ð°ÑÑÐ½Ð¾-Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ°ÑÑÐ¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð¾ÐºÐ°Ð·Ð°Ð»Ð¸, ÑÑÐ¾ ÑÑÑÐ¾Ðµ Ð¼Ð¾Ð»Ð¾ÐºÐ¾ Ð¾Ñ Ð¸Ð½ÑÐ¸ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ Ð²Ð¸ÑÑÑÐ¾Ð¼ Ð»ÐµÐ¹ÐºÐ¾Ð·Ð° ÐºÐ¾ÑÐ¾Ð² ÑÑÑÐµÑÑÐ²ÐµÐ½Ð½Ð¾ ÑÐ²ÐµÐ»Ð¸ÑÐ¸Ð²Ð°ÐµÑ ÑÐºÐ¾ÑÐ¾ÑÑÑ Ð¸ Ð¸Ð½ÑÐµÐ½ÑÐ¸Ð²Ð½Ð¾ÑÑÑ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð¾Ð¿ÑÑÐ¾Ð»Ð¸ Ñ Ð¼ÑÑÐµÐ¹. ÐÐ¸Ð¿ÑÑÐµÐ½Ð¸Ðµ Ð¸ Ð»Ð¸Ð¾ÑÐ¸Ð»Ð¸Ð·Ð°ÑÐ¸Ñ Ð¼Ð¾Ð»Ð¾ÐºÐ° Ð½Ðµ ÑÐ½Ð¸Ð¶Ð°ÐµÑ ÐµÐ³Ð¾ Ð¾ÑÑÐ¸ÑÐ°ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ Ð½Ð° Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð¼ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÑ. Ð¡Ð°Ð¼ÐºÐ¸ Ð¼ÑÑÐµÐ¹ Ð»Ð¸Ð½Ð¸Ð¸ Balb/c Ð±Ð¾Ð»ÐµÐµ Ð²Ð¾ÑÐ¿ÑÐ¸Ð¸Ð¼ÑÐ¸Ð²Ñ Ðº Ð»ÐµÐ¹ÐºÐ¾Ð·Ð½Ð¾Ð¼Ñ Ð¼Ð¾Ð»Ð¾ÐºÑ.
description: The subject of the graduate qualification work is: Â«The influence of bovine leukemia virus on the quality of milk products and the consumer's bodyÂ». The work is devoted to the scientific and theoretical study of the quality of milk depending on the infection of cows with the bovine leukemia virus based on literature review and to a scientific and practical study of the role of such milk in the oncogenesis of an inbred line of white mice BALB/c with a transplanted line of plasmacytoma (myeloma) cells Sp.2/0 â Ag.8. The experimental part of the research work was carried out on the basis of Â«ÐÐÐ ÐÐÐÐÐÐÐ-ÐÐ ÐÂ» and was carried out in accordance with the tasks set: an analysis of the epizootic situation was carried out in two farms that are unfavorable for bovine leukemia; a comparison was made of milk quality indicators from seronegative and seropositive cows based on literature review; a solid tumor was reproduced in Balb/c mice using a syngeneic plasmacytoma (myeloma) cell line Sp.2/0 â Ag.8; tumor development was studied depending on the administered dose of myeloma cells; the influence of milk introduced into the diet of animals from RID-positive cows of different treatment on tumor development in male and female mice of the Balb/c line was determined. Results of the scientific and practical part of the research have shown that raw milk from cows infected with bovine leukemia virus significantly increases the rate of tumor development in both male and female mice. Boiling and lyophilization of milk does not reduce its negative effect on the organism of animals. Balb/c female mice are more susceptible to milk from cows infected with bovine leukemia virus.