cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
L'habit fait le moine: Les discours sur l'apparence dans la France du XIIIe au XVe siècle
Creators: name: Pilon-David, Émilie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: History, European.

description: Les pouvoirs laïques et cléricaux dans la France du Bas Moyen Âge ont eu recours à tout un arsenal dans l'objectif de modeler une société encadrée, au sein de laquelle les individus détenaient une place assignée ne devant être transgressée. Le respect de ce cadre social et de l'ordre fut garanti entre autres par des marqueurs visuels importants, révélant les traits identitaires, tels le sexe, le statut social et l'appartenance à un groupe. Afin d'assurer le fonctionnement de cette société d'ordre, les autorités ont notamment eu recours aux discours sur l'habit afin d'imposer un cadre vestimentaire au moyen de lois ou par la diffusion d'un message moraliste chrétien. L'importance des discours tenus sur le costume, qui dans les derniers siècles du Moyen Âge constituait le marqueur visuel par excellence, soulève une question: le vêtement pouvait-il être considéré à l'époque comme un outil d'encadrement et de reproduction sociale? L'étude des discours laïques et cléricaux sur les vêtements révèle que les pouvoirs mirent de l'avant une discussion sur des aspects particuliers de l'habit, selon leurs préoccupations respectives. Bien que le message de l'Église et de la royauté diffère, leurs discours illustrent qu'à l'époque, l'habit était un marqueur identitaire puissant qu'il fallait contrôler. Cette recherche contribue à enrichir le domaine de l'anthropologie du vêtement et des mentalités médiévales en faisant la lumière sur le rôle de l'apparence dans la construction d'une société idéale imaginée par les pouvoirs de l'époque.
Supplementary document for Multi-port beamsplitters based on multi-core optical fibers for high-dimensional quantum information - 4548266.pdf
Creators: name: Lima, Gustavo
name: Cariñe, Jaime
name: Cañas, Gustavo
name: SKRZYPCZYK, Paul
name: Supic, Ivan
name: Guerrero, Nayda
name: García, Tania
name: Pereira, Luciano
name: Prosser, Miguel Solís
name: Xavier, Guilherme
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental material
Digitaler Wandel - Warum überhaupt noch Fremdsprachen in der Schule lernen?
Creators: name: Grünewald, Andreas
Publisher: name: Narr
Year: 2019
Subjects: subject: Digitalisierung
subject: Fremdsprachenunterricht
subject: Künstliche Intelligenz
subject: 400

description: Im vorliegenden Beitrag wird die Digitalisierung mit Blick auf den Fremdsprachenunterricht besprochen. Zunächst wird auf die Forschung zur fachspezifischen Digitalisierung Bezug genommen. Im Folgenden wird dann der Umgang mit Künstlichen Intelligenzen im Fremdsprachenunterricht diskutiert. Zuletzt wird eine Forderung zur Neuakzentuierung der Inhalte und Ziele des Fremdsprachenunterricht unter Betrachtung der Digitalisierung dargelegt.
title: EVERNOTE: Productividad aplicada al entorno radiológico.
Creators: name: Monedero Picazo, Maria
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Structured reporting
subject: Education
subject: Computer Applications-General
subject: Professional issues
subject: Computer applications

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
1.
Dar a conocer una aplicación multiplataforma que se está empezando a utilizar ampliamente tanto para mejorar la productividad personal como laboral. 2.
Describir los usos que se pueden dar a Evernote aplicadas al Radiodiagnóstico a nivel...
Integrated in silico strategy for PBT assessment and prioritization under REACH
Creators: name: Pizzo, Fabiola
name: Lombardo, Anna
name: Brandt, Marc
name: Manganaro, Alberto
name: Cappelli, Claudia I.
name: Petoumenou, Maria I.
name: Albanese, Federica
name: Roncaglioni, Alessandra
name: Benfenati, Emilio
Publisher: name: My University
Year: 2016
Subjects: Persistenz
Bioakkumulation
Toxizität

description: Chemicals may persist in the environment, bioaccumulate and be toxic for humans and wildlife, posing great concern. These three properties, persistence (P), bioaccumulation (B), and toxicity (T) are the key targets of the PBT-hazard assessment. The European regulation for the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) requires assessment of PBT-properties for all chemicals that are produced or imported in Europe in amounts exceeding 10 tonnes per year, checking whether the criteria set out in REACH Annex XIII are met, so the substance should therefore be considered to have properties of very high concern. Considering how many substances can fall under the REACH regulation, there is a pressing need for new strategies to identify and screen large numbers fast and inexpensively. An efficient non-testing screening approach to identify PBT candidates is necessary, as a valuable alternative to money- and time-consuming laboratory tests and a good start for prioritization since few tools exist (e.g. the PBT profiler developed by USEPA).
The aim of this work was to offer a conceptual scheme for identifying and prioritizing chemicals for further assessment and if appropriate further testing, based on their PBT-potential, using a non-testing screening approach. We integrated in silico models (using existing and developing new ones) in a final algorithm for screening and ranking PBT-potential, which uses experimental and predicted values as well as associated uncertainties. The Multi-Criteria Decision-Making (MCDM) theory was used to integrate the different values. Then we compiled a new set of data containing known PBT and non-PBT substances, in order to check how well our approach clearly differentiated compounds labeled as PBT from those labeled as non-PBT. This indicated that the integrated model distinguished between PBT from non-PBT compounds.
Quelle: http://www.sciencedirect.com
Progressive point-light-based global illumination
Creators: name: Dammertz, Holger
name: Keller, Alexander
name: Lensch, Hendrik P. A.
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 004 / Data processing & computer science
subject: Computer graphics
subject: Three-dimensional imaging. Data processing
subject: Gaphik
subject: Globale Beleuchtung
subject: Realistische Computergraphik
subject: Rendering
subject: Visualisierung

description: We present a physically-based progressive global illumination system that is capable of simulating complex lighting situations robustly by efficiently using both light and eye paths. Specifically, we combine three distinct algorithms: point-light-based illumination which produces low-noise approximations for diffuse inter-reflections, specular gathering for glossy and singular effects, and a caustic histogram method for the remaining light paths. The combined system efficiently renders low-noise production quality images with indirect illumination from arbitrary light sources including inter-reflections from caustics and allows for simulating depth of field and dispersion effects. Our system computes progressive approximations by continuously refining the solution using a constant memory footprint without the need of pre-computations or optimizing parameters beforehand.
title: Soil biodiversity: State-of-the-Art and possible implementation in chemical risk assessment
title: Soil biodiversity: State-of-the-Art and possible implementation in chemical risk assessment
titleType: AlternativeTitle
Creators: name: Gestel, Cornelis A.M. Van
name: Mommer, Liesje
name: Montanarella, Luca
name: Pieper, Silvia
Publisher: name: My University
Year: 2020

description: Protecting the structure and functioning of soil ecosystems is one of the central aims of current regulations of chemicals. This is, for instance, shown by the emphasis on the protection of key drivers and ecosystem services as proposed in the protection goal options for soil organisms by the European Food Safety Authority (EFSA). Such targets require insight into soil biodiversity, its role in the functioning of ecosystems, and the way it responds to stress. Also required are tools and methodologies for properly assessing biodiversity. To address these issues, the Society of Environmental Toxicology and Chemistry (SETAC) Europe 14th Special Science Symposium (SESSS14) was held 19 to 20 November 2019 in Brussels, Belgium. The central aim of the SESSS14 was to provide information on how to include soil biodiversity and soil functions as protection goal options in the risk assessment and quantification of the effects of chemicals and other stressors (including their respective regulations). This paper is based on the presentations and discussions at the SESSS14 and will give a brief update on the scientific state-of-the art on soil biodiversity, novel scientific developments, experimental and modeling approaches, as well as case studies. It will also discuss how these approaches could inform future risk assessment of chemicals and other stressors in the regulatory context of protecting soil ecosystems. © 2020 The Authors.
title: Anatomía de la Muñeca y Mano: ATLAS RADIOLÓGICO
Creators: name: Trinidad Rios, Sergio
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Musculoskeletal bone
subject: Musculoskeletal joint
subject: Musculoskeletal soft tissue
subject: Conventional radiography
subject: CT
subject: MR
subject: Education

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Proporcionar al Residente de Radiodiagnóstico un atlas anatómico de la muñeca y mano mediante diferentes técnicas de imagen: Radiología Convencional,
Ecografía,
TCMD y...
Court Culture as an Explanation of Case Processing Efficiency: An Exploratory Study of the Applicability of Leverick and Duff's Typology of Court Culture to Bail Courts in Ontario
Creators: name: Heath, Sarah
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Law.
subject: Sociology, Criminology and Penology.

description: In June 2008 the Ontario Ministry of the Attorney General announced their Justice on Target strategy to reduce the amount of time and number of appearances required to resolve a case in the Ontario criminal court system. The premise put forth by this strategy suggested that the structural and administrative changes implemented by the Ministry would elicit greater court efficiency. However, this belief is in contradiction to recent research on court delay which suggests that such changes are only effective when there is a court culture in place that supports such practices. This new literature emphasizes the central importance of a local informal discretionary system of expectations, norms and relationships on the efficiency of case processing. This thesis examines the possible relationship between court culture and court efficiency. Through a comparison of two Eastern Ontario bail courts, this study explores a number of cultural characteristics of both an efficient and less inefficient court that have been identified in previous research on court culture, most notably Leverick & Duff's (2002) analysis of passive and proactive Scottish magistrate courts. In particular, detailed qualitative and quantitative data were gathered for this purpose through semi-structured interviews with key stakeholders. The study found that the efficient court had more proactive indicators and the inefficient court had more passive indicators. This finding suggests that courts of varying efficiency have distinct cultures and that Leverick & Duff's passive-proactive typology is an effective tool for measuring court culture in Ontario bail courts.
title: RM cerebral en pacientes con cirrosis y caídas: alteración del fasciculo longitudinal superior en DTI y visuoespacial.
Creators: name: Nuñez Marín, Fidel
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology brain
subject: MR
subject: Computer Applications-General

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Evaluar las alteraciones cerebrales en RM y su relacion con la neuropsicología y la posible disfunción extrapiramidal,
en pacientes cirróticos con caídas,
comparándolos con un grupo pareado,
sin...
Chemical and electronic changes of the CeO2 support during CO oxidation on Au/CeO2 catalysts: time-resolved operando XAS at the Ce LIII Edge
Creators: name: Bansmann, Joachim
name: Abdel-Mageed, Ali M.
name: Chen, Shilong
name: Fauth, Corinna
name: Häring, Thomas
name: Kuˇcerová, Gabriela
name: Wang, Yuchen
name: Behm, Rolf Jürgen
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: CO oxidation
subject: Au/CeO2
subject: Ce LIII edge
subject: operando spectroscopy
subject: DDC 540 / Chemistry & allied sciences
subject: X-ray absorption near edge structure
subject: XANES

description: Abstract: While being highly active for the CO oxidation reaction already at low temperatures, Au/CeO2 catalysts su er from continuous deactivation with time on stream, with the activity and deactivation depending on the initial catalyst activation procedure. In previous X-ray absorption measurements at the Au LIII edge, which focused on changes in the electronic and geometric changes of Au, we found a modest increase of the Au particle size during reaction, with the Au nanoparticles (NPs) present in a dominantly metallic state during reaction, regardless of the pretreatment. Here we aim at expanding on these insights by examining the changes in electronic and chemical composition of the CeO2 support induced by di erent pretreatment procedures and during subsequent CO oxidation at 80 C, by following changes at the Ce LIII near edge region in time-resolved operando X-ray absorption measurements. The results indicate a strong dependence of the initial concentration of Ce3+ ions on the pretreatment, while during subsequent reaction this rapidly approaches a steady-state value which depends on the oxidative/reductive character of the reaction gas mixture, but is largely independent of the pretreatment. These results are discussed and related to earlier finding on the electronic properties of Au nanoparticles under identical reaction conditions.
title: Estimulación cerebral profunda en la Enfermedad de Parkinson: correlación entre la situación de los electrodos y la respuesta clínica.
Creators: name: Castrillo Maortua, Ana
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: MR
subject: Neuroradiology brain

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Correlacionar la situación definitiva de los electrodos de estimulación cerebral profunda con la escala UPDRS (Unified Parkinson´s Disease Rating Scale) y el registro neurofisiológico intraoperatorio. El subtálamo es la diana más...
Non contact all optical thermal conductivity measurement utilizing Raman spectroscopy
Creators: name: Kwiecinski, Przemyslaw Mark
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Physics, Condensed Matter.

description: Original experimental data for the temperature dependence of the Raman shift in silicon and gallium sulfide is presented. An all optical thermal conductivity method, using an equation presented by Perichon et a1.2 and Nonnenmacher et al. 23, is applied to silicon and gallium sulfide. Theoretical calculations by Moody et al.20 and Nissam et al. 22 are compared to the experimental results of Perichon et al. for the first time. The thermal conductivity of silicon is measured at 23°C, 200°C, and 300°C, and of gallium sulfide at 23°C. We investigate the possibility of measuring thermal conductivity at high pressures.
title: Utilidad de las técnicas de imagen en el TCE pediátrico
Creators: name: Vela Marin, Ana Carmen
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology brain
subject: Paediatric
subject: Trauma
subject: CT

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Determinar la necesidad de técnicas de imagen en pacientes pediátricos tras TCE. Valorar los signos clínicos sugestivos de patología...
Input–output Gaussian channels: theory and application
Creators: name: Tufarelli, Tommaso
name: Retzker, Alex
name: Plenio, Martin B
name: Serafini, Alessio
Publisher: name: Universität Ulm
Year: 2012
Subjects: subject: DDC 530 / Physics
subject: Trapped ions
subject: Ionenfalle

description: Abstract Setting off from the classic input–output formalism, we develop a theoretical framework to characterize the Gaussian quantum channels relating the initial correlations of an open bosonic system to those of properly identified output modes. We then proceed to apply our formalism to the case of quantum harmonic oscillators, such as the motional degrees of freedom of trapped ions or nanomechanical oscillators, interacting with travelling electromagnetic modes through cavity fields and subject to external white noise. We thus determine the degree of squeezing that can be transferred from an intra-cavity oscillator to light and show that the intra-cavity squeezing can be transformed into distributed optical entanglement if one can access both output fields of a two-sided cavity.
Supplementary document for Multi-port beamsplitters based on multi-core optical fibers for high-dimensional quantum information - 4548266.pdf
Creators: name: Lima, Gustavo
name: Cariñe, Jaime
name: Cañas, Gustavo
name: SKRZYPCZYK, Paul
name: Supic, Ivan
name: Guerrero, Nayda
name: García, Tania
name: Pereira, Luciano
name: Prosser, Miguel Solís
name: Xavier, Guilherme
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplemental material
Searching For and Timing Millisecond Pulsars
Creators: name: Spiewak, Renee
Publisher: name: Swinburne
Year: 2024

description: Millisecond pulsars are highly magnetised, rapidly rotating stellar remnants, produced in supernovae and later spun up to milisecond periods by companion stars. Studies of millisecond pulsars to date have revealed complex properties and left unanswered questions about the emission mechanism, population statistics, and evolution models. This thesis pursues these questions in three related studies using the Parkes radio telescope and the new MeerKAT array. I highlight an interesting source, PSR J2322-2650, and some theoretical implications. I further conduct a census of millisecond pulsars with MeerKAT and present a comprehensive dataset on which future studies may be based.
In vivo Downregulation of MHC Class I Molecules by HCMV Occurs During All Phases of Viral Replication but Is Not Always Complete
Creators: name: Gabor, Florin
name: Jahn, Gerhard
name: Sedmak, Daniel D.
name: Sinzger, Christian
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: immune evasion
subject: MHC class I
subject: antigen presentation
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Cytomegalovirus
subject: Immunohistochemistry
subject: Antigens
subject: Cytomegalie-Virus
subject: Immunohistologie
subject: Antigen

description: Based on cell culture data, MHC class I downregulation by HCMV on infected cells has been suggested as a means of immune evasion by this virus. In order to address this issue in vivo, an immunohistochemical analysis of tissue sections from biopsy and autopsy materials of HCMV infected organs was performed. HCMV antigens from the immediate early, early, and late phase of viral replication, and cellular MHC class I molecules were detected simultaneously or in serial sections by immuno-peroxidase and immuno-alkaline phosphatase techniques. Investigated organs included lung, gastrointestinal tract, and placenta. Colocalization of MHC molecules with sites of viral replication as well as MHC expression in individual infected cells were analyzed. To detect immune effector cells at sites of viral replication, leukocytes, CD8+ lymphocytes, and HCMV antigens were stained in serial sections. While strong MHC class I expression was detected in the cells surrounding infected cells, it appeared downregulated in the majority of infected cells themselves, particularly in the late replication phase. Despite significantly reduced MHC class I signals on infected cells, sites of infection were infiltrated by inflammatory cells that consisted predominantly of CD8+ lymphocytes. The extent of inflammatory infiltrates was negatively correlated with the extent of HCMV infected cells. Taken together, our findings indicate that HCMV can downmodulate MHC class I expression in vivo, whereas cytokines originating from infiltrating immune effector cells probably up regulates MHC class I expression in noninfected bystander cells. The presence of cytotoxic lymphocytes in close contact to infected cells may reflect control of viral spread by these cells despite MHC class I downmodulation.
Supplementary document for mHealth spectroscopy of blood hemoglobin with spectral super-resolution - 4549476.pdf
Creators: name: Park, Sang Mok
name: Onufrak, Michelle Visbal
name: Haque, Md
name: Were, Martin
name: Naanyu, Violet
name: Hasan, Kamrul
name: Kim, Young
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary Figures, Supplementary Tables, Supplementary Methods
Galaxy and mass assembly: The 1.4 GHz SFR indicator, SFR-M∗ relation and predictions for ASKAP-GAMA
Creators: name: Davies, L. J. M.
name: Huynh, M. T.
name: Hopkins, A. M.
name: Seymour, N.
name: Driver, S. P.
name: Robotham, A. G. R.
name: Baldry, I. K.
name: Bland-Hawthorn, J.
name: Bourne, N.
name: Bremer, M. N.
name: Brown, M. J. I.
name: Brough, S.
name: Cluver, Michelle
name: Grootes, M. W.
name: Jarvis, M.
name: Loveday, J.
name: Moffet, A.
name: Phillipps, S.
name: Owers, M.
name: Sadler, E.
name: Wang, L.
name: Wilkins, S.
name: Wright, A.
Publisher: name: Swinburne
Year: 2024

description: We present a robust calibration of the 1.4 GHz radio continuum star formation rate (SFR) using a combination of the Galaxy And Mass Assembly (GAMA) survey and the Faint Images of the Radio Sky at Twenty-cm (FIRST) survey. We identify individually detected 1.4 GHz GAMA-FIRST sources and use a late-type, non-active galactic nucleus, volume-limited sample from GAMA to produce stellar mass-selected samples. The latter are then combined to produce FIRST-stacked images. This extends the robust parametrization of the 1.4 GHz-SFR relation to faint luminosities. For both the individually detected galaxies and our stacked samples, we compare 1.4 GHz luminosity to SFRs derived from GAMA to determine a new 1.4 GHz luminosity-to-SFR relation with well-constrained slope and normalization. For the first time, we produce the radio SFR-M* relation over 2 decades in stellar mass, and find that our new calibration is robust, and produces a SFR-M* relation which is consistent with all other GAMA SFR methods. Finally, using our new 1.4 GHz luminosity-to-SFR calibration we make predictions for the number of star-forming GAMA sources which are likely to be detected in the upcoming Australian Square Kilometre Array Pathfinder surveys, Evolutionary Map of the Universe and Deep Investigation of Neutral Gas Origins.
Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers
Creators: name: Frick, Petra
name: Sellier, Chantal
name: Mackenzie, Ian R A
name: Cheng, Chieh-Yu
name: Tahraoui-Bories, Julie
name: Martinat, Cecile
name: Pasterkamp, R. J
name: Prudlo, Johannes
name: Edbauer, Dieter
name: Oulad-Abdelghani, Mustapha
name: Feederle, Regina
name: Charlet-Berguerand, Nicolas
name: Neumann, Manuela
Publisher: name: BioMed Central
Year: 2018

description: Hexanucleotide repeat expansion in C9orf72 is the most common genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis, but the pathogenic mechanism of this mutation remains unresolved. Haploinsufficiency has been proposed as one potential mechanism. However, insights if and how reduced C9orf72 proteins levels might contribute to disease pathogenesis are still limited because C9orf72 expression, localization and functions in the central nervous system (CNS) are uncertain, in part due to the poor specificity of currently available C9orf72 antibodies. Here, we generated and characterized novel knock-out validated monoclonal rat and mouse antibodies against C9orf72. We found that C9orf72 is a low abundant, cytoplasmic, highly soluble protein with the long 481 amino acid isoform being the predominant, if not exclusively, expressed protein isoform in mouse tissues and human brain. As consequence of the C9orf72 repeat expansion, C9orf72 protein levels in the cerebellum were reduced to 80% in our series of C9orf72 mutation carriers (n = 17) compared to controls (n = 26). However, no associations between cerebellar protein levels and clinical phenotypes were seen. Finally, by utilizing complementary immunohistochemical and biochemical approaches including analysis of human iPSC derived motor neurons, we identified C9orf72, in addition to its association to lysosomes, to be localized to the presynapses and able to interact with all members of the RAB3 protein family, suggestive of a role for C9orf72 in regulating synaptic vesicle functions by potentially acting as guanine nucleotide exchange factor for RAB3 proteins. In conclusion, our findings provide further evidence for haploinsufficiency as potential mechanism in C9orf72 pathogenesis by demonstrating reduced protein levels in C9orf72 mutation carriers and important novel insights into the physiological role of C9orf72 in the CNS. Moreover, the described novel monoclonal C9orf72 antibodies will be useful tools to further dissect the cellular and molecular functions of C9orf72.
Investigation of Self-Concept in Bipolar Disorder: Moving Beyond Traditional Self-Related Cognitions Towards Metacognitions
Creators: name: Yang, Yan
Publisher: name: Swinburne
Year: 2024

description: Intuitively speaking, one’s perceptions of the self are closely intertwined with their affective experiences. The current project provides insight to the complex interactions between various self-related cognitions and mood pathology for individuals with bipolar disorder. The project also explores therapeutic benefits for this clinical population of self-compassion and nonattachment to self, both of which aim to cultivate an adaptive relationship to the self. Overall, the project moves beyond traditional models and constructs of self-concept in bipolar disorder literature. Current findings inform future therapy designs that seek to utilise self-compassion and nonattachment to self as psychological treatment of bipolar disorder.
Bacterial colonization of irrigation fluid during aseptic revision knee arthroplasty
Creators: name: Fuchs, Michael
name: Pumberger, Matthias
name: Hommel, Hagen
name: Perka, Carsten
name: Von Roth, Philipp
name: Thiele, Kathi
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: surgical contamination
subject: irrigation liquid
subject: fluid reservoirs
subject: total knee replacement
subject: DDC 610 / Medicine & health
subject: Prosthesis-related infections
subject: Joint prosthesis; Adverse effects
subject: Arthroplasty, Replacement, Knee
subject: Periprothetische Infektion
subject: Kniegelenkprothese

description: Surgical risk factors for periprosthetic joint infection (PJI) after total knee arthroplasty (TKA) are the subjects of ongoing research. It is unclear if there are specific locations of the surgical area that might act as a pathogen source. Due to the fact that bacterial replication occurs preferably under humid conditions, it was our aim to investigate if irrigation fluid reservoirs on the surgical covers are subject to bacterial colonization. We prospectively observed 40 patients with scheduled aseptic 1-stage TKA revision. At time intervals of 30 min, irrigation samples were tested for microbiological colonization. Additionally, the suction tip was investigated at the end of surgery. Overall, a bacterial detection rate of 25% was found (57/232 samples). Analysis for any positive microbial detection revealed pathogen findings of irrigation fluid in 41.7% of samples after 30 min with a constant increase up to 77.8% after 90 min. Twenty-three percent of suction tips showed bacterial colonization. Coagulase-negative staphylococci, accounting for the majority of PJI, were the predominant pathogens. After an average follow-up of 17 months, no PJI was confirmed. Despite the substantial bacterial load of irrigation fluid, PJI rates were not elevated. Nevertheless, we recommend that irrigation fluid reservoirs should be prevented and not withdrawn by suction.
Supplementary document for mHealth spectroscopy of blood hemoglobin with spectral super-resolution - 4549476.pdf
Creators: name: Park, Sang Mok
name: Onufrak, Michelle Visbal
name: Haque, Md
name: Were, Martin
name: Naanyu, Violet
name: Hasan, Kamrul
name: Kim, Young
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplementary Figures, Supplementary Tables, Supplementary Methods
title: 3D ultrasound biomicroscopy for assessment of cartilage repair tissue
title: volumetric characterisation and correlation to established classification systems
titleType: Subtitle
Creators: name: Schoene, M.
name: Maennicke, N.
name: Somerson, J. S.
name: Marquass, B.
name: Henkelmann, R.
name: Aigner, T.
name: Raum, K.
name: Schulz, R. M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Objective and sensitive assessment of cartilage repair outcomes lacks suitable methods. This study investigated the feasibility of 3D ultrasound biomicroscopy (UBM) to quantify cartilage repair outcomes volumetrically and their correlation with established classification systems. 32 sheep underwent bilateral treatment of a focal cartilage defect. One or two years post- operatively the repair outcomes were assessed and scored macroscopically (Outerbridge, ICRS-CRA), by magnetic resonance imaging (MRI, MOCART), and histopathology (O'Driscoll, ICRS-I and ICRS-II). The UBM data were acquired after MRI and used to reconstruct the shape of the initial cartilage layer, enabling the estimation of the initial cartilage thickness and defect volume as well as volumetric parameters for defect filling, repair tissue, bone loss and bone overgrowth. The quantification of the repair outcomes revealed high variations in the initial thickness of the cartilage layer, indicating the need for cartilage thickness estimation before creating a defect. Furthermore, highly significant correlations were found for the defect filling estimated from UBM to the established classification systems. 3D visualisation of the repair regions showed highly variable morphology within single samples. This raises the question as to whether macroscopic, MRI and histopathological scoring provide sufficient reliability. The biases of the individual methods will be discussed within this context. UBM was shown to be a feasible tool to evaluate cartilage repair outcomes, whereby the most important objective parameter is the defect filling. Translation of UBM into arthroscopic or transcutaneous ultrasound examinations would allow non-destructive and objective follow-up of individual patients and better comparison between the results of clinical trials.
Linear and nonlinear finite strip analysis of bridges.
Creators: name: Li, Wenchang.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1991
Subjects: subject: Engineering, Civil.

description: The analysis of highway bridges such as slab-on-girder bridges, box-girder bridges, cable-stayed bridges etc. is a very complicated undertaking. Analytical methods are applicable only for the simplest structures. Finite element method is the most powerful and versatile tool, which can be applied to analyze any types of bridge and any load cases. However, the efficiency of that method needs to be improved because the finite element solutions usually require too much computer time, too large core storage and too many input data. If a structure has a uniform cross-section and line end supports (in fact, a high proportion of bridges can be simplified to such a structure), the finite strip method has proven to be the most efficient numerical structural analysis method, which employs a series of functions to simulate the variation of displacements in the longitudinal direction of the structure. Thus, the number of dimensions of analysis is reduced by at least one. Consequently, the computer time, storage and input data are reduced significantly. Since this method was first published in 1968, it has been extensively used for linear and nonlinear, static and dynamic analysis of rectangular, skew and curved slab bridges, slab-on girder bridges box-girder bridges etc. In the present study, the following efforts are made: (1) Extending the finite strip method to the analysis of continuous haunched slab-on-girder bridges and box-girder bridges. (2) Extending the spline finite strip method to the analysis of continuous haunched slab-on-girder bridges and box-girder bridges. (3) Extending the finite strip method to nonlinear analysis of cable-stayed bridges. (4) Improving the efficiency of geometrically nonlinear finite strip analysis of plates. (5) Improving the accuracy of materially nonlinear finite strip analysis of reinforced concrete slabs. (6) Combining the finite strip method with finite element method and boundary element method for analysis of rectangular plates with some irregularities. A number of numerical examples will show the accuracy and efficiency of the methods developed in the present study.
Sleep Apnea-Hypopnea Quantification by Cardiovascular Data Analysis
Creators: name: Camargo, Sabrina
name: Riedl, Maik
name: Anteneodo, Celia
name: Kurths, Jürgen
name: Penzel, Thomas
name: Wessel, Niels
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2014
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Sleep disorders are a major risk factor for cardiovascular diseases. Sleep apnea is the most common sleep disturbance and its detection relies on a polysomnography, i.e., a combination of several medical examinations performed during a monitored sleep night. In order to detect occurrences of sleep apnea without the need of combined recordings, we focus our efforts on extracting a quantifier related to the events of sleep apnea from a cardiovascular time series, namely systolic blood pressure (SBP). Physiologic time series are generally highly nonstationary and entrap the application of conventional tools that require a stationary condition. In our study, data nonstationarities are uncovered by a segmentation procedure which splits the signal into stationary patches, providing local quantities such as mean and variance of the SBP signal in each stationary patch, as well as its duration . We analysed the data of 26 apneic diagnosed individuals, divided into hypertensive and normotensive groups, and compared the results with those of a control group. From the segmentation procedure, we identified that the average duration , as well as the average variance , are correlated to the apnea- hypoapnea index (AHI), previously obtained by polysomnographic exams. Moreover, our results unveil an oscillatory pattern in apneic subjects, whose amplitude is also correlated with AHI. All these quantities allow to separate apneic individuals, with an accuracy of at least . Therefore, they provide alternative criteria to detect sleep apnea based on a single time series, the systolic blood pressure.
title: Closing gaps for environmental risk screening of engineered nanomaterials
title: Closing gaps for environmental risk screening of engineered nanomaterials
titleType: AlternativeTitle
Creators: name: Hellack, Bryan
name: Kühnel, Dana
name: Nickel, Carmen
name: Kussatz, Carola
name: Zalm, Esther Van Der
name: Zalm, Esther Van Der
Publisher: name: My University
Year: 2019
Subjects: Nanomaterialien
Gefahr

description: Engineered nanomaterials (ENM) have a widespread presence in human life and are components of many products and applications. This warrants an easy and fast evaluation of potential environmental risks. However, so far this is hampered by the multitude of different nanomaterials on the markets in addition to the many variations in form, size and surface modifications. Testing of each variation of ENM is not manageable, and hence the development and application of fast risk screening tools for ENMs is discussed. Here, we present the development of a scoring scheme with regard to ENM environmental risks under consideration of the two compartments water and soil. It allows for the ranking of ENM according to their environmental fate and hazard by taking into account criteria that are meaningful and relevant for ENM. The selection of the criteria is based on conceptual considerations, existing knowledge, and experimental work including transport and transformation studies as well as aquatic and terrestrial toxicity tests. The allocation of the ENM to the scores informs on the potential for transport and transformation and the hazard potential. Fate and hazard scores are subsequently combined into one risk score (1â€Ì10 for aquatic compartment, 1â€Ì7 for terrestrial compartment). The risk score has the intention to indicate which ENM may need prioritization for further action, i.e. with regard to the degree of detail for further testing or modelling. The applicability and consistency of the scoring schemes were assessed by taking different chemical species (e.g. of Ag, TiO2, SiO2, Cu, Fe) of ENM in various modifications (e.g. different shapes and coatings) into account. In conclusion, the established scoring schemes were found to be applicable to rank ENM according to their environmental fate and hazard potential, and thus to their environmental risk potential. © 2019 The Authors. Published by Elsevier B.V.
Urinary Vitamin D Binding Protein and KIM-1 Are Potent New Biomarkers of Major Adverse Renal Events in Patients Undergoing Coronary Angiography
Creators: name: Chaykovska, Lyubov
name: Heunisch, Fabian
name: Einem, Gina Von
name: Alter, Markus L.
name: Hocher, Carl-Friedrich
name: Tsuprykov, Oleg
name: Dschietzig, Thomas
name: Kretschmer, Axel
name: Hocher, Berthold
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Vitamin-D-binding protein (VDBP) is a low molecular weight protein that is filtered through the glomerulus as a 25-(OH) vitamin D 3/VDBP complex. In the normal kidney VDBP is reabsorbed and catabolized by proximal tubule epithelial cells reducing the urinary excretion to trace amounts. Acute tubular injury is expected to result in urinary VDBP loss. The purpose of our study was to explore the potential role of urinary VDBP as a biomarker of an acute renal damage. Method We included 314 patients with diabetes mellitus or mild renal impairment undergoing coronary angiography and collected blood and urine before and 24 hours after the CM application. Patients were followed for 90 days for the composite endpoint major adverse renal events (MARE: need for dialysis, doubling of serum creatinine after 90 days, unplanned emergency rehospitalization or death). Results Increased urine VDBP concentration 24 hours after contrast media exposure was predictive for dialysis need (no dialysis: 113.06 ± 299.61ng/ml, n = 303; need for dialysis: 613.07 ± 700.45 ng/ml, n = 11, Mean ± SD, p<0.001), death (no death during follow-up: 121.41 ± 324.45 ng/ml, n = 306; death during follow-up: 522.01 ± 521.86 ng/ml, n = 8; Mean ± SD, p<0.003) and MARE (no MARE: 112.08 ± 302.00ng/ml, n = 298; MARE: 506.16 ± 624.61 ng/ml, n = 16, Mean ± SD, p<0.001) during the follow-up of 90 days after contrast media exposure. Correction of urine VDBP concentrations for creatinine excretion confirmed its predictive value and was consistent with increased levels of urinary Kidney Injury Molecule-1 (KIM-1) and baseline plasma creatinine in patients with above mentioned complications. The impact of urinary VDBP and KIM-1 on MARE was independent of known CIN risk factors such as anemia, preexisting renal failure, preexisting heart failure, and diabetes. Conclusions Urinary VDBP is a promising novel biomarker of major contrast induced nephropathy-associated events 90 days after contrast media exposure.
The influence of threat-induced anxiety on inhibitory control, sustained brain responses, and the changes associated with impulsivity and addiction
Creators: name: Roxburgh, Ariel
Publisher: name: Swinburne
Year: 2024

description: The thesis explores the behavioural and neurobiological relationship between anxiety and self-control. The thesis found that anxiety impairs self-control, and that this impairment is underpinned by neurobiological changes in areas associated with self-control. Further, the thesis found that anxiety is associated with neurobiological changes that favour action-readiness. The thesis discusses the implication of these findings in relation to those with addiction. This thesis improves society’s understanding of how two important features of psychological disorders (anxiety and impaired self-control) interact, which may lead to more targeted treatments for those who have disorders characterised by both features.
title: A phased approach for preparation and organization of human biomonitoring studies
title: A phased approach for preparation and organization of human biomonitoring studies
titleType: AlternativeTitle
Creators: name: Fiddicke, Ulrike
name: Kolossa-Gehring, Marike
name: Pack, Kim Laura
name: Tolonen, Hanna
Publisher: name: My University
Year: 2021

description: Background Human biomonitoring (HBM) studies like other epidemiological studies are costly and time-consuming. They require the administration of questionnaires and collection of biological samples, putting substantial burden on the participants which may result in low participation rates. The growing importance of HBM studies in epidemiology, exposure assessment and risk assessment underline the importance of optimizing study planning, designing and implementation thus minimizing the above-mentioned difficulties. Methods Based on frameworks from survey design and fieldwork preparation of the European Joint Program HBM4EU, the German Environment Surveys and the COPHES/DEMOCOPHES twin projects combined with elements of project management strategies, a Phased Approach has been developed, introducing a step-by-step guideline for the development of epidemiological studies. Results The Phased Approach splits the process of developing a study into six phases: Phase 0 (Scoping and Planning): All aspects that are necessary to conduct a study are compiled and put on the agenda for decision-making. Phase 1 (Preparation and Testing): Instruments (e.g. questionnaires), materials (e.g. guidelines, information), and ethics and data management issues, needing thorough preparation and testing before a study can start. Phase 2 (Initiation): Organization and acquisition of necessary equipment and engaging and training personnel. Phase 3 (Implementation): All procedures that require temporal proximity to the start date of fieldwork, such as obtaining contact information of invitees. Phase 4 (Fieldwork and Analysis): Involvement of participants and chemical analysis of the collected samples. Phase 5 (Results and Evaluation): Final procedures leading to closure of the project, such as providing and communicating results. Conclusions The separation of the planning and conduct of human biomonitoring studies into different phases creates the basis for a structured procedure and facilitates a step-by-step approach reducing costs, warranting high participation rates and increasing quality of conduct. Emphasis is put on a comprehensive scoping phase ensuring high quality of the study design, which is indispensable for reliable results. © 2021 The Authors.
Man as he is: Politics and propriety in the thought of David Hume
Creators: name: Sheppard, K. N
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Philosophy.
subject: History, General.

description: This thesis considers propriety and politics in the thought of David Hume. It argues that Hume's political thought was intimately connected with his philosophical investigation of the 'science of man', first undertaken in A Treatise of Human Nature (17 39-40). It outlines how the 'science of man' progressed from Pyrrhonian scepticism to a 'mitigated' scepticism that affirmed 'common life' and moderation. A principle factor in this development was the articulation of sympathy and a philosophy of sentiment, consistent with, yet critical of, earlier philosophical traditions. This moderate scepticism was accompanied by the early articulation of Hume's enlightened scale of values---amusement, virtue, understanding, moderation. In highlighting these values this study argues that Hume be considered an establishment thinker, connecting philosophical values to a political context where stability was a mainstay of debate. Thus, the thesis complements both Duncan Forbes and J. G. A. Pocock, scholars who have argued along similar grounds that Hume's self-conceived revolution in philosophy ironically investigated the concept of revolution in political terms, but failed to give it any hearty endorsement. This study also casts light upon how Hume offered his philosophical investigations to a broader eighteenth-century audience and why an endorsement of political revolution was not to be found in this work. It suggests that the Essays, Moral, Political, and Literary represent Hume's attempt to cultivate a political culture of politeness and moderation, containing, as they do, a critique of superstition and enthusiasm, both religious and political. (Abstract shortened by UMI.)
Understanding and Improving Student Engagement in Employability Initiatives: A Study of Business Undergraduates
Creators: name: Fish, Nicola
Publisher: name: Swinburne
Year: 2024

description: Nicola investigated student engagement in employability development initiatives to evaluate the effectiveness of the employability approach within a case. The study found students exhibited both affective and behavioural barriers to engaging in the development of their employability. Findings of the study demonstrate the need for the theoretical constructs of engagement, employability and career development learning to intersect and inform a consolidated approach to university learning and teaching practice.