cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Sculture nel verde. Le prime esposizioni all’aperto di scultura contemporanea: le esperienze italiane in relazione alla scena europea (1948 – 1957)
Creators: name: Torre, Paola
Publisher: name: Sezione di Lettere
Year: 2019
Subjects: scultura; ambiente

description: This contribution focuses on the analysis of the origin and diffusion of the open air sculpture exhibitions, in Europe and in Italy. The article intends to explain how and where this particular type of exposition was born and in which way it changed the museologists’ and artists’ approach to the organization of sculpture exhibitions. In this sense, it contributed to create a new connection between sculptures and nature, not only intended in its concept of “space”, but also of “place”. The London exposition in Battersea Park in 1948 can be considered the first example of open air sculpture exhibition; it became a model for the successive exhibitions as Sonsbeek ‘49 in Arnhem and Exposition internationale en plein air de sculpture 1900-1950 in the Middelheim Park of Antwerp. At the same time, the diffusion of the open air sculpture exhibitions took place in Italy; in 1949 and in 1953 two major exposition of international contemporary sculpture have been organized in Villa Mirabello’s gardens in Varese. In 1957, another important open air sculpture exhibition — completely dedicated to the Italian contemporary sculpture — was organized in Villa Mazzini’s garden, in Messina.
description: Sezione di Lettere, XIII (2018)
Flavonoid content of the Libyan Onosma Cyrenaicum: isolation, identification, electronic chemical reactivity, drug likeness, docking, and MD study
Creators: name: Elkwafi, Ghazala
name: Mohamed, Najwa
name: Elabbar, Fakhri
name: Alnajjar, Radwan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: In this work, an attempt to identify the flavonoid content of the Libyan Onosma Cyrenaicum led to the isolation of three flavonoids 7,8-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one(GE-001), 5,7-dihydroxy-2-(3-hydroxy-4-methoxy phenyl)-4H-chromen-4-one (GE-002) and 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one (GE-003), the isolated compounds were characterized using 1H and 13C-NMR techniques. A further DFT study at ωB97-XD with 6-311++G** basis set in water was conducted to calculate the isolated compounds’ global and local reactivity descriptors and Fukui indices along with their antioxidant activity. The drug-likeness and bioactivity properties of the isolated compounds were estimated and discussed. Finally, GE-001, GE-002, and GE-003 were docked into HCV NS5B polymerase active siteand this was followed by molecular dynamic simulation to certify the obtained docking result and to obtain the MM-GBSA free binding energyy of the isolated compounds. Communicated by Ramaswamy H. Sarma
(500900) Wilfred Earle Wickham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Normal Metal Hot-Electron Nanobolometer with Johnson Noise Thermometry Readout
Creators: name: Karasik, Boris S.
name: McKitterick, Christopher B.
name: Reck, Theodore J.
name: Prober, Daniel E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The sensitivity of a THz hot-electron nanobolometer (nano-HEB) made from a normal metal is analyzed. Johnson Noise Thermometry (JNT) is employed as a readout technique. In contrast to its superconducting TES counterpart, the normal-metal nano-HEB can operate at any cryogenic temperature depending on the required radiation background limited Noise Equivalent Power (NEP). It does not require bias lines; 100s of nano-HEBs can be read by a single low-noise X-band amplifier via a filter bank channelizer. The modeling predicts that even with the sensitivity penalty due to the amplifier noise, an NEP ~ 10$^{-20}$ - 10$^{-19}$ W/Hz$^{1/2}$ can be expected at 50-100 mK in 10-20 nm thin titanium (Ti) normal metal HEBs with niobium (Nb) contacts. This NEP is fairly constant over a range of readout frequencies ~ 10 GHz. Although materials with weaker electron-phonon coupling (bismuth, graphene) do not improve the minimum achievable NEP, they can be considered if a larger than 10 GHz readout bandwidth is required.
description: 5 pages, 5 figures, presented at the 25th International Symposium on Space Terahertz Technology (Moscow, Russia, 27-30 April 2014)
(500901) Ellen Wickham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Manifestazioni di creatività “imprevista” nell’arte delle donne in Italia negli anni Settanta. Ketty La Rocca e Irma Blank: operare tra gesto e linguaggio
Creators: name: Iaquinta, Caterina
Publisher: name: Sezione di Lettere
Year: 2019
Subjects: Art and Feminism - Women Artists - Performance - Gesture - Arte italiana - Anni Settanta

description: The paper analyses the Italian historical-artistic context in the Seventies with reference to the role played by women. The most debated issues surrounding the manifestation of female creativity are reinterpreted in a performative key, understood as a form of gesture. In this perspective there is a focus on the work of Ketty La Rocca and Irma Blank during the Seventies, based for both on the disarticulation and decomposition of language and, consequently, of dominant communication systems.
description: Sezione di Lettere, XIII (2018)
Late Pleistocene slip on a low-angle normal fault, Searles Valley, California
Creators: name: Didericksen, B.
name: Kirby, E.
name: Numelin, T.
name: Walker, J.D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: The mechanical feasibility of normal-sense slip on low-angle faults remains a conundrum in extensional tectonics. The rarity of demonstrably active low-angle normal faults may imply that very specifi c criteria must be satisfi ed for signifi cant fault displacement. We present new geologic observations, geomorphic mapping, and structural analysis for a low-angle fault zone along the eastern margin of Searles Valley, California. Our observations indicate that Pleistocene displacement along the range-front fault scarps is the near-surface expression of slip on a bedrock-rooted low-angle normal fault. Along the central portion of the range front in Searles Valley, high-angle faults offset late Pleistocene alluvial and lacustrine surfaces. These faults merge downward into a westdipping, low-angle fault, but do not displace the low-angle surface. These geometric relations are satisfi ed only when displacement on the high-angle faults is accommodated by slip on the basal low-angle fault. We use displaced alluvial fan surfaces to determine slip rates across the fault system over late Pleistocene to Holocene time. Combining radiocarbon ages of lacustrine tufa deposits with high-precision topographic surveys of fault scarps yields average slip rates of 0.21- 0.35 m/k.y. Additional mapping of faults within the Slate Range at the northern end of Searles Valley suggests that slip is transferred northward to the Manly Pass fault, a bedrock normal fault that trends northeast into Panamint Valley. Thus, although displacement along the range-front fault system dies out northward, we infer that active deformation occurs within the range and likely links extension in Searles Valley with deformation in Panamint Valley.
Francesca Gallo, Raffaella Perna (a cura di), Ketty La Rocca 80. Gesture, speech and word, catalogo della mostra, XVII Biennale Donna, Ferrara, Padiglione d’Arte Contemporanea, 15 aprile - 3 giugno 2018, Cartografica, Ferrara 2018, pp. 124. ISBN 978-88-8863-038-0
Creators: name: Pocaterra, Caterina
Publisher: name: Sezione di Lettere
Year: 2019

description: Sezione di Lettere, XIII (2018)
Application and network layers design for wireless sensor network to supervise chemical active product warehouse
Creators: name: Zouinkhi, Ahmed
name: Mekki, Kais
name: Abdelkrim, Mohamed Naceur
Publisher: name: arXiv
Year: 2015
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Wireless sensor networks have profound effects on many application fields like security management which need an immediate and fast system reaction. Indeed, the monitoring of a dangerous product warehouse is a major issue in chemical industry field. This paper describes the design of chemical warehouse security system using the concept of active products and wireless sensor networks. A security application layer is developed to supervise and exchange messages between nodes and the control center to prevent industrial accident. Different security rules are proposed on this layer to monitor the internal state and incompatible products distance. If a critical event is detected, the application generates alert message which need a short end to end delay and low packet loss rate constraints by network layer. Thus, a QoS routing protocol is also developed in the network layer. The proposed solution is implemented in Castalia/OMNeT++ simulator. Simulation results show that the system reacts perfectly for critical event and can meet the QoS constraints of alert message.
description: 20 pages in International Journal of Computer Science, Engineering and Applications (IJCSEA), Vol.4, No.6, December 2014, pp. 53-72
(500899) Lucy Trotman Wickham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Tratti binari e tratti monovalenti nella rappresentazione delle vocali
Creators: name: Bafile, Laura
Publisher: name: Sezione di Lettere
Year: 2020
Subjects: Binary features – Element Theory; Vowels; Vowel Harmony; Metaphony

description: The paper deals with the nature of segmental primitives. Although the conception of features as binary units has dominated phonological literature for decades, it has been challenged in convincing ways by the alternative theory according to which primitives are monovalent units. The paper compares the two aforementioned approaches by focusing on the representation of vowels. I will argue in favour of the unarist conception through a discussion of data concerning vowel harmony and metaphony in Italo-Romance varieties
description: Sezione di Lettere, XIV (2019)
Una proposta per Mazzolino giovane: il San Rocco della Pinacoteca Nazionale di Ferrara
Creators: name: Lapierre, Valentina
Publisher: name: Sezione di Lettere
Year: 2020
Subjects: Renaissance painting; Ludovico Mazzolino; Pinacoteca Nazionale di Ferrara; Iconography of Saint Roch

description: The attribution proposed in this paper attempts to add a new piece to the reconstruction of the early production of the Ferrarese painter Ludovico Mazzolino (circa 1480 – circa 1528/1530), often coincident with the commission of works intended for public fruition, usually of a large format. The few figurative testimonies that remain from this period – prior to 1509 of the first work dated with certainty, the Berlin Triptych – have focused the attention of critics on the subsequent, more recognizable, production of mostly small-format paintings, while it remains uncertain the identification of the oldest proofs of the artist
description: Sezione di Lettere, XIV (2019)
title: Streamflow Projections to Inform Climate-Adapted Culvert Designs in Washington State
Creators: name: Rogers, Matt
name: Thebo, Anne
name: Mauger, Guillaume
Publisher: name: University of Washington Climate Impacts Group
Year: 2023

description: We analyzed and updated peak flow projections for Washington state using a new streamflow projection dataset: The River Management Joint Operating Committee’s version 2 hydrologic projections (RMJOC-II, https://www.hydro.washington.edu/CRCC, Chegwidden et al. 2019). This new dataset assesses future changes for multiple climate models, downscalings and hydrologic modeling approaches. Based on the findings we provided recommendations for estimating the central tendency and uncertainty of this dataset and discussed the benefits and drawbacks of different regionalization schemes.
Eloquenza di Gorgia, eloquenza di Lisia: il Gorgia e il Fedro nel De audiendo plutarcheo
Creators: name: Berardi, Elisabetta
Publisher: name: Sezione di Lettere
Year: 2020
Subjects: Sophists and Philosophical Education; Competition and Rivalry; Plutarch’s de audiendo; Plato, Gorgias and Phaedrus; Euripides’ Antiope

description: In competitive dialogue with the emerging Second Sophistic, Plutarch rewrites in a strongly allusive way Platonic images that highlighted the rivalry between rhetoric and philosophy and the seduction of the rhetorical ἐπίδειξις. Plutarch intends to refer subtly to two Plato’s works frequented by the schools of eloquence, the Gorgias and the Phaedrus. When he warns young people of the risks of Atticism, which obscures the content of the message by giving prominence to its form, Plutarch leaves the readers themselves to recognize images of known Platonic ancestry thanks to the common rhetorical παιδεία.
description: Sezione di Lettere, XIV (2019)
Dipole polarizability of 120Sn and nuclear energy density functionals
Creators: name: Hashimoto, T.
name: Krumbholz, A. M.
name: Reinhard, P. -G.
name: Tamii, A.
name: von Neumann-Cosel, P.
name: Adachi, T.
name: Aoi, N.
name: Bertulani, C. A.
name: Fujita, H.
name: Fujita, Y.
name: Ganioǧlu, E.
name: Hatanaka, K.
name: Iwamoto, C.
name: Kawabata, T.
name: Khai, N. T.
name: Krugmann, A.
name: Martin, D.
name: Matsubara, H.
name: Miki, K.
name: Neveling, R.
name: Okamura, H.
name: Ong, H. J.
name: Poltoratska, I.
name: Ponomarev, V. Yu.
name: Richter, A.
name: Sakaguchi, H.
name: Shimbara, Y.
name: Shimizu, Y.
name: Simonis, J.
name: Smit, F. D.
name: Süsoy, G.
name: Thies, J. H.
name: Suzuki, T.
name: Yosoi, M.
name: Zenihiro, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The electric dipole strength distribution in 120Sn between 5 and 22 MeV has been determined at RCNP Osaka from a polarization transfer analysis of proton inelastic scattering at E_0 = 295 MeV and forward angles including 0°. Combined with photoabsorption data an electric dipole polarizability α_D(120Sn) = 8.93(36) fm^3 is extracted. The dipole polarizability as isovector observable par excellence carries direct information on the nuclear symmetry energy and its density dependence. The correlation of the new value with the well established α_D(208Pb) serves as a test of its prediction by nuclear energy density functionals (EDFs). Models based on modern Skyrme interactions describe the data fairly well while most calculations based on relativistic Hamiltonians cannot.
description: 6 pages, 4 figures
(500896) Ellen Trotman
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Schulen und mehrsprachige Lebenswelten. Erfahrungen im Umgang mit (il)legitimen Sprachen
Creators: name: Zingg, Irene
Publisher: name: :unas
Year: 2023

description: Die kumulative Dissertation spiegelt die theoretische und angewandte Tätigkeit wider, insbesondere in Bezug auf die Themen Migration und Mehrsprachigkeit, interkulturelle Bildung sowie Bildung und sozialer Gerechtigkeit in einer transnationalisierten und super-diversen Schweiz, deren demografische Zusammensetzung sich seit Ende der 1990er Jahre stark verändert hat. Ausgangspunkt ist Bourdieus Unterscheidung zwischen legiti-men und illegitimen Sprachen, welche die De-Kapitalisierung von Migrationssprachen im Schweizer Bildungssystem systematisch dokumentiert und das brachliegende pädagogi-sche Potenzial der Mehrsprachigkeit in der heranwachsenden Migrationsbevölkerung auf-zeigt.
description: La thèse de doctorat cumulative reflète l'activité théorique et appliquée, en particulier en ce qui concerne les thèmes liés à la migration et au plurilinguisme, à l'éducation intercultu-relle ainsi qu'à l'éducation et à la justice sociale dans une Suisse transnationalisée et su-perdiversifiée, dont la composition démographique a fortement changé depuis la fin des années 1990. Le point de départ est la distinction faite par Bourdieu entre langues légi-times et illégitimes, qui documente systématiquement la décapitalisation des langues de la migration dans le système scolaire suisse et montre le potentiel pédagogique inexploité du plurilinguisme dans la population migrante en pleine croissance.
description: The cumulative dissertation reflects theoretical and applied activity especially in relation to topics dealing with migration and multilingualism, intercultural education, and education and social justice in a transnationalized and superdiverse Switzerland whose demograph-ic composition has changed significantly since the late 1990s. The starting point is Bour-dieu's distinction between legitimate and illegitimate languages, which systematically doc-uments the de-capitalization of migrant languages in the Swiss school education system and highlights the untapped pedagogical potential of multilingualism in the adolescent migrant population.
Peephole Optimization for Quantum Approximate Synthesis
Creators: name: Clark, Joseph
name: Thapliyal, Himanshu
Publisher: name: arXiv
Year: 2024
Subjects: subject: Quantum Physics (quant-ph)
subject: Emerging Technologies (cs.ET)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Peephole optimization of quantum circuits provides a method of leveraging standard circuit synthesis approaches into scalable quantum circuit optimization. One application of this technique partitions an entire circuit into a series of peepholes and produces multiple approximations of each partitioned subcircuit. A single approximation of each subcircuit is then selected to form optimized result circuits. We propose a series of improvements to the final phase of this architecture, which include the addition of error awareness and a better method of approximating the correctness of the result. We evaluated these proposed improvements on a set of benchmark circuits using the IBMQ FakeWashington simulator. The results demonstrate that our best-performing method provides an average reduction in Total Variational Distance (TVD) and Jensen-Shannon Divergence (JSD) of 18.2% and 15.8%, respectively, compared with the Qiskit optimizer. This also constitutes an improvement in TVD of 11.4% and JSD of 9.0% over existing solutions.
description: 8 pages, 4 figures, 1 table
(500898) Charles Bertram Wickham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Evolution and identification of DREB transcription factors in the wheat genome: modeling, docking and simulation of DREB proteins associated with salt stress
Creators: name: Hassan, Sameer
name: Berk, Katrin
name: Aronsson, Henrik
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: Computational Biology

description: Soil salinity and the resulting salt stress it imposes on crop plants is a major problem for modern agriculture. Understanding how salt tolerance mechanisms in plants are regulated is therefore important. One regulatory mechanism is the APETALA2/Ethylene Responsive Factor (AP2/ERF) transcription factor family, including dehydration responsive element binding (DREB) transcription factors. By binding to DNA, specifically upstream of genes that play roles in salt tolerance pathways, DREB proteins upregulate expression of these genes. DREB in Triticum aestivum (wheat) cluster in sub-groups and in this study by scanning the recently extended predicted proteome of wheat for DREB, we increased the number of members of this sub-family. Using the wheat genome, we identified 576 genes coding for the AP2 domain of which 508 were identified to have one AP2 domain, a characteristic of the DREB/ERF subfamily. We confirmed the existing four sub-groups by sequence-based phylogenetic analyses but also identified 32 new DREB subfamily members, not belonging to any known sub-group. Transcription factor profile inference analysis identified two genes, TraesCS2B02G002700 and TraesCS2D02G015200, being homologous to DREB1A of Arabidopsis thaliana. Based on molecular simulation (25 ns) analysis, TraesCS2B02G002700 with a CCGAC motif was observed to interact very stably with DNA. In silico mutational analysis at the 19th position in the DREB domain of TraesCS2B02G002700-DNA complex indicated this as a stable part for recognizing and forming interaction with DNA. Moreover, six target genes were predicted having an upstream CCGAC motif regulated by TraesCS2B02G002700. Our study provides an overall framework for exploring the transcription factors in plants and identifying e.g. potential salt stress target genes. Communicated by Ramaswamy H. Sarma
Binding and inhibitory effect of ravidasvir on 3CLpro of SARS-CoV‐2: a molecular docking, molecular dynamics and MM/PBSA approach
Creators: name: Bera, Krishnendu
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Drug repurposing requires a limited resource, cost-effective and faster method to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therefore, this in silico studies attempts to identify the drug-likeness properties of ravidasvir, an II/III phase clinical trial chronic hepatitis C drug against 3-Chymotrypsin-like protease (3CLpro) of SARS-CoV-2 to combat the ongoing coronavirus disease 2019 (COVID-19) pandemic. This protease is predominantly involved in virus replication cycle; hence it is considered as a potent drug target. The molecular docking results showed that ravidasvir was found to be potent inhibitors of 3CLpro with scoring function based binding energy is −26.7 kJ/mol. Further dynamic behaviour of apo form and complex form of ravidasvir with 3CLpro were studied using molecular dynamics (MD) simulations over 500 ns each, total 2 µs time scale. The motion of the protein was studied using principal component analysis of the MD simulation trajectories. The binding free energy calculated using MM/PBSA method from the MD simulation trajectory was −190.3 ± 70.2 kJ/mol and −106.0 ± 26.7 kJ/mol for GROMOS96 54A7 and AMBER99SB-ILDN force field, respectively. This in silico studies suggesting ravidasvir might be a potential lead molecule against SARS-CoV-2 for further optimization and drug development to combat the life-threatening COVID-19 pandemic. Communicated by Ramaswamy H. Sarma
Characteristics of steady state fluvial topography above fault-bend folds
Creators: name: Kirby, E.
name: Miller, S.R.
name: Slingerland, R.L.
Publisher: name: Blackwell Publishing Ltd
Year: 2007

description: In steady state convergent orogens, erosion balances lateral as well as vertical bedrock motions. For simple geometrical reasons, the difference between the total steady state erosion flux and its vertical component is up to 30% for typical fluvial slopes and bedrock streamline inclinations, suggesting that lateral advection is also likely to be expressed topographically. In order to understand these geomorphologic consequences, we focus on steady state topography developed on active fault-bend folds. First, we derive an analytical solution for the slopes of detachment-limited streams that incorporates lateral advection. Next, we conduct experiments using a numerical two-dimensional landscape evolution model (Channel-Hillslope Integrated Landscape Development model (CHILD)) incorporating linear diffusion on hillslopes and detachment-limited stream channel incision above a fault-bend fold. The concavity and steepness indices of steady state long profiles are functions of bedrock velocity magnitude and direction, streamflow direction, and fluvial erosivity. Asymmetry of mountain range profiles varies as a function of fluvial erosivity or bedrock velocity only if we account for the lateral velocity component. This asymmetry is equally sensitive to this lateral component, fluvial incision, and hillslope diffusion. However, the effect of diffusion on drainage divide position is significant only at high diffusivities, short length scales, low bedrock advection rates, or relatively low fluvial erosivity. Thus in most mountain ranges and fault blocks, drainage divide migration is expected to be dictated by stream channel erosion. Model results are shown to be consistent with topography in the Siwalik Hills, Nepal, which overlie fault-bend folds produced above the frontal fault systems in the Himalayan foreland.
(500893) Lucy Newsham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Verification of Programs by Combining Iterated Specialization with Interpolation
Creators: name: De Angelis, Emanuele
name: Fioravanti, Fabio
name: Navas, Jorge A.
name: Proietti, Maurizio
Publisher: name: arXiv
Year: 2014
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences
subject: D.2.4; F.3.1; I.2.2

description: We present a verification technique for program safety that combines Iterated Specialization and Interpolating Horn Clause Solving. Our new method composes together these two techniques in a modular way by exploiting the common Horn Clause representation of the verification problem. The Iterated Specialization verifier transforms an initial set of verification conditions by using unfold/fold equivalence preserving transformation rules. During transformation, program invariants are discovered by applying widening operators. Then the output set of specialized verification conditions is analyzed by an Interpolating Horn Clause solver, hence adding the effect of interpolation to the effect of widening. The specialization and interpolation phases can be iterated, and also combined with other transformations that change the direction of propagation of the constraints (forward from the program preconditions or backward from the error conditions). We have implemented our verification technique by integrating the VeriMAP verifier with the FTCLP Horn Clause solver, based on Iterated Specialization and Interpolation, respectively. Our experimental results show that the integrated verifier improves the precision of each of the individual components run separately.
description: In Proceedings HCVS 2014, arXiv:1412.0825
Evolution and identification of DREB transcription factors in the wheat genome: modeling, docking and simulation of DREB proteins associated with salt stress
Creators: name: Hassan, Sameer
name: Berk, Katrin
name: Aronsson, Henrik
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: Computational Biology

description: Soil salinity and the resulting salt stress it imposes on crop plants is a major problem for modern agriculture. Understanding how salt tolerance mechanisms in plants are regulated is therefore important. One regulatory mechanism is the APETALA2/Ethylene Responsive Factor (AP2/ERF) transcription factor family, including dehydration responsive element binding (DREB) transcription factors. By binding to DNA, specifically upstream of genes that play roles in salt tolerance pathways, DREB proteins upregulate expression of these genes. DREB in Triticum aestivum (wheat) cluster in sub-groups and in this study by scanning the recently extended predicted proteome of wheat for DREB, we increased the number of members of this sub-family. Using the wheat genome, we identified 576 genes coding for the AP2 domain of which 508 were identified to have one AP2 domain, a characteristic of the DREB/ERF subfamily. We confirmed the existing four sub-groups by sequence-based phylogenetic analyses but also identified 32 new DREB subfamily members, not belonging to any known sub-group. Transcription factor profile inference analysis identified two genes, TraesCS2B02G002700 and TraesCS2D02G015200, being homologous to DREB1A of Arabidopsis thaliana. Based on molecular simulation (25 ns) analysis, TraesCS2B02G002700 with a CCGAC motif was observed to interact very stably with DNA. In silico mutational analysis at the 19th position in the DREB domain of TraesCS2B02G002700-DNA complex indicated this as a stable part for recognizing and forming interaction with DNA. Moreover, six target genes were predicted having an upstream CCGAC motif regulated by TraesCS2B02G002700. Our study provides an overall framework for exploring the transcription factors in plants and identifying e.g. potential salt stress target genes. Communicated by Ramaswamy H. Sarma
Il Protesilao lucianeo e il destino della sua sposa: l’ambientazione cronologica dei Dialoghi dei morti 27 e 28
Creators: name: Dolcetti, Paola
Publisher: name: Sezione di Lettere
Year: 2020
Subjects: Lucian of Samosata; Dialogues of the Dead; Protesilaus; Trojan war

description: Lucian dedicates the Dialogues of the Dead 27 and 28 to Protesilaus. In the first dialogue the hero tries to find out where the responsability of his destiny, that deprived him of his wife, lies. In the latter, he begs Pluto to allow him to come back among the living men for a day: so he could see his wife again. The two Dialogues are connected by the identity of the leading character as well as by a close net of intertextual references, but are different from a chronological point of view: in Dialogue 28 the hero has just arrived in Hades, while the Dialogue 27, which seems at first sight to be placed in the eternal present of the afterlife, could be placed instead at a later stage of the mythical story when Protesilaus' expectations are disappointed and all the protagonists of the Trojan expedition are already dead.
description: Sezione di Lettere, XIV (2019)
Transient channel incision along Bolinas Ridge, California: Evidence for differential rock uplift adjacent to the San Andreas fault
Creators: name: Johnson, C.
name: Heimsath, A.
name: Furlong, K.
name: Kirby, E.
Publisher: name: Blackwell Publishing Ltd
Year: 2007

description: The rates and spatial distribution of active deformation provide critical constraints on the geodynamics of deforming lithosphere, yet such data are often difficult to acquire in eroding landscapes where poor preservation of geomorphic or stratigraphic markers hinders strain reconstruction. Recent advances in understanding of the relationship between bedrock channel profile form and erosion rate have led to their use as an index of rock uplift rate in steady state landscapes. Here we extend this analysis to landscapes experiencing a transient increase in erosion rate using an example from the Marin County region of northern California. We characterize channel and hillslope gradients in a series of small watersheds along a monolithologic portion of the Franciscan terrane in Marin County. Channel steepness indices vary strongly from north to south along the ridge and correspond with the progressive development of relief on threshold hillslopes along valley walls. These patterns argue that recent channel incision has engendered a transient adjustment of hillslope gradient, as incision outpaces soil production rates. These differences in landscape form and inferred incision rate are explained by differential rock uplift within the region east of the San Andreas fault. Relationships between channel gradient and incision rate suggest a threefold to fivefold difference in incision rate across the region and place a minimum bound on differential rock uplift rates. Our study highlights how landscape analysis can place bounds on the distribution of Earth deformation in both space and time and thus lends insight into the processes driving that deformation.
Binding and inhibitory effect of ravidasvir on 3CLpro of SARS-CoV‐2: a molecular docking, molecular dynamics and MM/PBSA approach
Creators: name: Krishnendu Bera
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Drug repurposing requires a limited resource, cost-effective and faster method to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therefore, this in silico studies attempts to identify the drug-likeness properties of ravidasvir, an II/III phase clinical trial chronic hepatitis C drug against 3-Chymotrypsin-like protease (3CLpro) of SARS-CoV-2 to combat the ongoing coronavirus disease 2019 (COVID-19) pandemic. This protease is predominantly involved in virus replication cycle; hence it is considered as a potent drug target. The molecular docking results showed that ravidasvir was found to be potent inhibitors of 3CLpro with scoring function based binding energy is −26.7 kJ/mol. Further dynamic behaviour of apo form and complex form of ravidasvir with 3CLpro were studied using molecular dynamics (MD) simulations over 500 ns each, total 2 µs time scale. The motion of the protein was studied using principal component analysis of the MD simulation trajectories. The binding free energy calculated using MM/PBSA method from the MD simulation trajectory was −190.3 ± 70.2 kJ/mol and −106.0 ± 26.7 kJ/mol for GROMOS96 54A7 and AMBER99SB-ILDN force field, respectively. This in silico studies suggesting ravidasvir might be a potential lead molecule against SARS-CoV-2 for further optimization and drug development to combat the life-threatening COVID-19 pandemic. Communicated by Ramaswamy H. Sarma
Leaky modes of waveguides as a classical optics analogy of quantum resonances
Creators: name: Cruz, Sara Cruz y
name: Rosas-Ortiz, Oscar
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: A classical optics waveguide structure is proposed to simulate resonances of short range one-dimensional potentials in quantum mechanics. The analogy is based on the well known resemblance between the guided and radiation modes of a waveguide with the bound and scattering states of a quantum well. As resonances are scattering states that spend some time in the zone of influence of the scatterer, we associate them with the leaky modes of a waveguide, the latter characterized by suffering attenuation in the direction of propagation but increasing exponentially in the transverse directions. The resemblance is complete since resonances (leaky modes) can be interpreted as bound states (guided modes) with definite lifetime (longitudinal shift). As an immediate application we calculate the leaky modes (resonances) associated with a dielectric homogeneous slab (square well potential) and show that these modes are attenuated as they propagate.
description: The title has been modified to describe better the contents of the article. Some paragraphs have been added to clarify the results
Jihad im Moro-Land? Interdisziplinäres Forschungskolloquium zum Konflikt um die islamische Minderheit in den Süd-Philippinen
Creators: name: Graf, Arndt
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2022

description: ASIEN: The German Journal on Contemporary Asia, Nr. 97 (2005): ASIEN (Oktober)
Monte Carlo calculation of total skin electron therapy dose using whole-body photogrammetry models
Creators: name: Crowe, Scott
name: Cassim, Naasiha
name: Luscombe, Jenna
name: McMahon, Katie
name: Kairn, Tanya
Publisher: name: Zenodo
Year: 2024
Subjects: radiation therapy
total skin electron therapy
Monte Carlo
absorbed dose

description: Presentation slides describing Monte Carlo modelling of total skin electron therapy treatment dose for a Varian TrueBeam using whole body photogrammetry scans.
Transient fluvial incision in the headwaters of the Yellow River, northeastern Tibet, China
Creators: name: Reiser, U.
name: Kirby, E.
name: Robinson, R.
name: Harkins, N.
name: Heimsath, A.
Publisher: name: Blackwell Publishing Ltd
Year: 2007

description: We utilize topographic analysis of channel profiles combined with field measurements of erosion rates to explore the distribution of channel incision in the Anyemaqen Shan, a broad mountainous region in the northeastern Tibetan plateau. Tributary channels to the Yellow River display systematic downstream increases in channel gradient associated with convex upward longitudinal profiles. Steep lower reaches of channels are associated with rapid (>1 m/ka) incision rates along the Yellow River, while upstream reaches are associated with relatively slow (0.05-0.1 m/ka) erosion of soil-mantled uplands. Covariance between erosion rates and channel steepness indices suggest that channels are adjusted to match long-wavelength differential rock uplift across the range. Geologic constraints indicate that rapid incision downstream of the range is associated with excavation of basin fill driven by changes in relative base level farther downstream. The upstream limit of this wave of transient incision is marked by a series of knickpoints that are found at nearly the same elevation throughout the watershed, consistent with knickpoint migration as a kinematic, rather than diffusional, wave. Tributary channel gradients downstream of knickpoints, however, display a progressive adjustment to increased incision rates that may reflect the influence of increased sediment flux. Comparison of observed channel profiles to a stream power model of fluvial behavior reveals that the rate of knickpoint propagation can only be explained if the erosional efficiency coefficient (K) increases during incision. Our results thus highlight the utility of channel profile analysis to reconstruct the fluvial response to both active tectonism and external changes in base level.
Alcuni riusi classici ne L’inamoramento de Orlando
Creators: name: Irmici, Virgilio
Publisher: name: Sezione di Lettere
Year: 2020
Subjects: Intertestualità; Boiardo; Omero; Virgilio; Intertextuality; Boiardo; Homer; Vergil

description: L’articolo individua gli ipotesti classici soggiacenti ad alcuni passi dell’Inamoramento de Orlando. The paper discusses some classical echoes in Boiardo’s L’inamoramento de Orland
description: Sezione di Lettere, XIV (2019)
Applied Mathematical Modelling in Evolutionary Biochemistry
Creators: name: Sarkar, Proshanta
name: Joshi, Amit
Publisher: name: figshare
Year: 2023
Subjects: Biomedical engineering not elsewhere classified

description: This paper explores the use of applied mathematical modelling in the field of evolutionary biochemistry. The authors demonstrate how mathematical models can be applied to better understand the complex processes of evolution and biochemistry, and provide insights into the mechanisms of evolutionary change. The study uses a range of mathematical techniques, including dynamic systems analysis, statistical analysis, and computational simulation, to gain a deeper understanding of the relationships between different components of evolutionary biochemistry. The results of the study show that mathematical modelling can be a powerful tool for advancing our knowledge in this field and have implications for the development of new evolutionary biochemistry theories and applications.
(500895) Edward Trotman George Wickham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Jane Austen, scrittrice professionista nel periodo della Reggenza
Creators: name: Panin, Sabrina
Publisher: name: Sezione di Lettere
Year: 2020
Subjects: Jane Austen’s publications; women writers; publishing system; Regency England; circulating libraries

description: The paper aims to discuss the publishing system during the Regency and more precisely Jane Austen’s publications. The text is divided into three parts. The first one deals with women writers’ conditions and the obstacles that they have to overcame in order to publish their manuscripts. The second part is about the different types of publication available during the Regency and the last one follows Jane Austen’s career and the difficulties she has suffer to publish her novels. The study is based upon the information taken from scholar’s studies, Jane Austen’s books and letters, and also from the biographical anecdotes about her life that her siblings have written.
description: Sezione di Lettere, XIV (2019)