cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Free Women and the Making of Colonial Jamaican Economy and Society 1760-1834
Creators: name: Trahey, Erin Malone
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: women
slavery
Caribbean history
colonial Jamaica

description: This study considers the social and economic lives of free women in Jamaica from 1760 to 1834. Throughout the period studied Jamaica was Britain’s most important imperial holding. The colony’s slave economy, driven by the labour of hundreds of thousands of enslaved men and women, generated incredible wealth. Still, Jamaica was the deadliest place to live in British America. Due to the endemic nature of tropical disease and atrocious mortality rates, neither the enslaved population nor the white population maintained itself naturally prior to emancipation. However, an environment characterized by death and demographic crisis engendered heightened opportunities for women to take part in tropical enterprise and to shape the futures of their families. Inheritance norms were weakened by the omnipresence of death, precipitating more generous inheritance bequests for women and a greater role given to wives and daughters—both white women, and those of mixed-race descent—in tropical commerce. Additionally, as slave ownership was not limited by gender or race, free women of all races took part in the slave economy. Free women’s visibility in the island’s formal as well as informal economies, and the wealth accumulated by some, was unsurpassed in a British American context. However, in this slave society, free women’s prosperity rested upon the exploitation and oppression of others. In contrast to familiar historical trajectories that have presented Caribbean participation in Atlantic markets of slavery and capital as male-driven ventures, this study argues that free women of all races were vital participants in the slave economy and principle beneficiaries of plantation profits. This project moves beyond previous studies on women in colonial Jamaica by revealing how women’s enterprise and relations with one another shaped the nature of this economy and society, including the commercial, familial and kin networks that bound it together. In doing so, it enhances our understanding of this colony and the operation of race and gendered power within it.
The Research Progress of the Cold Chain Logistics of Agricultural Products
Creators: name: QIE, Haituo
name: QIE, Haituo
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Cold chain of agricultural products
subject: Cold chain logistics
subject: Cold chain prospects

description: This article is based on the result of the research findings about cold chain logistics of agricultural products of many experts and scholars. It analyzes three aspects of cold chain logistics of agricultural products: relevant concepts about cold chain logistics, existing problems and suggestions for improvement of it. While reviewing the experts’ views of the second question, this article comes up with some of my views of it and finally puts forth the recommendations for improvement about cold chain logistics of agricultural products based on the market and experts’ views, in order to provide a reference for relevant enterprises.
Functional analysis of Shigella encoded IpaH E3 ubiquitin ligases in cell-autonomous immunity
Creators: name: Pathe, Claudio
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: cell-autonomous immunity
Shigella flexneri
E3 ubiquitin ligase
host-pathogen interaction

description: Shigella flexneri is a highly adapted pathogen that invades the host cytosol and causes bacillary dysentery. Shigella has evolved powerful countermeasures to disarm host defense mechanisms; amongst them a family of twelve bacterial E3 ubiquitin ligases (IpaH) that are structurally unrelated to eukaryotic enzymes. IpaH ligases are injected into the host cytosol via the bacterial type III secretion system (T3SS) to manipulate the host cell and counteract anti-bacterial defense pathways. My work demonstrated that IFN-induced guanylate-binding proteins (GBPs) are novel targets for IpaH9.8. GBPs inhibit actin-dependent motility and cell-to-cell spread of bacteria unless they are ubiquitylated by IpaH9.8 and consequently degraded by the proteasome. IpaH9.8 targets GBP1, GBP2, and GBP4, thereby causing a transient poly-ubiquitin coat comprising K48 and K27-linked chains around S. flexneri, which leads to the proteasome-dependent destruction of existing GBP coats and the re-establishment of bacterial motility and cell-to-cell spread. So far, ubiquitylation of bacteria has mostly been associated with anti-bacterial autophagy or immune signaling. However, the ubiquitin coat assembled around intracellular Shigella by IpaH effectors, in particular IpaH9.8, serves a pro-bacterial function, the first observed so far. In addition, I characterized IpaH1.4 and IpaH2.5 for their ability to prevent NF-κB activation by targeting LUBAC. I found that IpaH1.4 specifically binds the LUBAC component HOIP and mediates its proteasomal degradation, thus abolishing linear ubiquitylation of bacteria and consecutive NF-κB activation via NEMO and autophagy induction via optineurin. Lastly, I identified novel potential ubiquitylation targets for IpaH effectors in human cells using a mass spectrometry-based approach. The resulting IpaH interactome presents the groundwork for further investigations and will help to identify potentially unknown cellular defense mechanisms that are antagonized by Shigella flexneri.
description: Boehringer Ingelheim Fonds
TURIZM TARMOG'IDA INNOVATSIYALARNI JALB ETISHDA MUTAXASISLARNI ROLI.
Creators: name: Komolov, Sadriddin
Publisher: name: Zenodo
Year: 2025

description: Ush bu maqolada, xozirgi globallashuv sharoitida mamlakatimiz iqtisodiyotni ravnaq topishida barcha sohalar kabi turizm sanoati tarmog‘ining milliy iqtisodiyotidagi ulushini oshirida innovatsiyalar joriy etish orqali raqobatbardoshlikni oshirish, xizmat sifatlarini yaxshilashda mutaxasislarni tutgan o‘rni hamda sohada ularning ahamiyati haqida tahlil qilishga harakat qilingan.
title: 02_1376
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: LaMOP

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
MOESM6 of GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients
Creators: name: Neckmann, Ulrike
name: Wolowczyk, Camilla
name: Hall, Martina
name: Almaas, Eivind
name: Ren, Jiang
name: Zhao, Sen
name: Johannessen, Bjarne
name: Skotheim, Rolf
name: Bjørkøy, Geir
name: Dijke, Peter
name: Holien, Toril
Publisher: name: figshare
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Plant Biology

description: Additional file 6: Table S4. The 50 top-scoring genes that are co-expressed with GREM1 in breast cancer. Co-expression analysis of the 50 top-scoring hits that are found co-expressed with GREM1 in a search of 331 breast cancer data sets in the SEEK database.
title: Das Lastpfad und Knotenmodell - Eine Erweiterung des C&C²-Ansatzes zur Bewertung von Ersatzgrößen in der Produktentwicklung mechatronischer Systeme
Creators: name: Vogel, Sven
Publisher: name: UNSPECIFIED
Year: 2021

description: Die Motivation für diese Arbeit ergibt sich aus dem steigenden Bedarf an Daten, die für die Digitalisierung der Industrie genutzt werden können. Für viele EntwicklerIn-nen von technischen Systemen ist die Erfassung von Prozess- und Zustandsgrößen je-doch noch Neuland und die Integration von Sensoren wird von vielen Unternehmen als zu kostspielig bei zu geringem Mehrwert empfunden. Es fehlt an Erfahrung, mit welchen Ersatzgrößen die gewünschten Prozess- und Zustandsgrößen indirekt und kostengünstig gemessen werden können. Die bestehenden Hilfsmittel in Form von Katalogen sind für das Finden von Sensoren für die entsprechenden Messgrößen gedacht, unterstützen je-doch nicht bei der Auswahl der passenden Ersatzgrößen. Abhilfe kann durch Modelle und Methoden geschafft werden, die den Zusammenhang zwischen der bestehenden Gestalt und der Messbarkeit von Prozess- und Zustandsgrößen darstellen. Der Contact & Channel-Ansatz (C&C²-Ansatz) bietet sich als ein entsprechendes Metamodell für die Analyse von Systemen an. Jedoch können mittels C&C²-Ansatz ledig-lich Messgrößen gefunden werden, die an Gestaltelementen anzufinden sind, die direkt mit der Funktion der Leitung der Größe zusammenhängen. In dieser Forschungsarbeit wird der C&C²-Ansatz um die Elemente Wandlung und Umformung erweitert. Dies ermöglicht, gezielt Reaktionen zu identifizieren, die an Ge-staltelementen der sekundären Funktionen gemessen werden können. Es wird gezeigt, welche Besonderheiten beim Umformen, Wandeln und bei parallelen Lastpfaden berück-sichtigt werden müssen. Zusätzlich wird beschrieben, wie mögliche Störgrößen für den Vergleich verschiedener Ersatzgrößen genutzt werden können. Anhand dieser Ergebnisse wird das Lastpfad- und Knotenmodell als Weiterent-wicklung des C&C²-Ansatzes vorgestellt, das als Metamodell Regeln für die Bildung von Analysemodellen liefert, die bei der Suche nach Ersatzgrößen unterstützen. Die Abbildung mittels Lastpfad- und Knotenmodells wird anhand von zwei technischen Produkten gezeigt, indem aus der Literatur bekannte Ersatzgrößen für die gewünschten Prozessgrößen nachgebildet werden. Die Anwendbarkeit bzw. die Wirkung der Anwendung des Lastpfad- und Knoten-modells wird anhand einer Probandenstudie gezeigt. In dieser Probandenstudie wird die Auswahl der Ersatzgröße von ProbandInnen ohne Kenntnis des Lastpfad- und Knoten-modells mit der Auswahl von Ersatzgrößen von ProbandInnen mit Kenntnis des Last-pfad- und Knotenmodells verglichen. Eine statistisch signifikante Verbesserung in der Auswahl der Ersatzgrößen der ProbandInnen, die auf die Kenntnis des Lastpfad- und Knotenmodells zurückzuführen ist, zeigt, dass eine Verbesserung der sensorischen Wei-terentwicklung von technischen Produkten mithilfe des Lastpfad- und Knotenmodells erzielt werden kann.
Additional file 2 of The anti-aging factor Klotho protects against acquired long QT syndrome induced by uremia and promoted by fibroblast growth factor 23
Creators: name: Navarro-García, José Alberto
name: Salguero-Bodes, Rafael
name: González-Lafuente, Laura
name: Martín-Nunes, Laura
name: Rodríguez-Sánchez, Elena
name: Bada-Bosch, Teresa
name: Hernández, Eduardo
name: Mérida-Herrero, Evangelina
name: Praga, Manuel
name: Solís, Jorge
name: Arribas, Fernando
name: Bueno, Héctor
name: Kuro-O, Makoto
name: Fernández-Velasco, María
name: Ruilope, Luis Miguel
name: Delgado, Carmen
name: Ruiz-Hurtado, Gema
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. Macroscopic and biochemical parameters in Klotho hypomorphic mice.
Review of Researches on Agricultural Industry Chain at Home and Abroad
Creators: name: Song, Ge
name: Yang, Taiyan
name: Liu, Jianhui
name: Song, Ge
name: Yang, Taiyan
name: Liu, Jianhui
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Agricultural industry chain
subject: Integration and optimization
subject: Promotion and extension
subject: Influencing factors
subject: Risk prevention

description: Management of agricultural industry chain is the main form of modern agricultural industrialization. Integration and optimization of agricultural chain have great significance in deepening the reform in the countryside, quickening the development of agricultural modernization and establishing new system of agricultural management. Based on the theory sources and contents of agricultural chain as well as the current researches at home and abroad, this paper hackles and concludes information technology, logistics management and food safety and quality in foreign agricultural chain as well as the organization model, operation mechanism, integration and optimization, promotion and extension, financing and risk prevention, influencing factors as well as performance evaluation in domestic agricultural chain and offers relevant review in order to provide further reference for future researches.
MOESM2 of From cytogenetics to cytogenomics: whole-genome sequencing as a first-line test comprehensively captures the diverse spectrum of disease-causing genetic variation underlying intellectual disability
Creators: name: Lindstrand, Anna
name: Eisfeldt, Jesper
name: Pettersson, Maria
name: Carvalho, Claudia
name: Kvarnung, Malin
name: Giedre Grigelioniene
name: Britt-Marie Anderlid
name: Bjerin, Olof
name: Gustavsson, Peter
name: HammarsjĂś, Anna
name: Georgii-Hemming, Patrik
name: Iwarsson, Erik
name: Johansson-Soller, Maria
name: Lagerstedt-Robinson, Kristina
name: Lieden, Agne
name: MĂĽns Magnusson
name: Martin, Marcel
name: Malmgren, Helena
name: NordenskjĂśld, Magnus
name: Ameli Norling
name: Ellika Sahlin
name: Stranneheim, Henrik
name: Tham, Emma
name: Wincent, Josephine
name: Ygberg, Sofia
name: Wedell, Anna
name: Wirta, Valtteri
name: Nordgren, Ann
name: Lundin, Johanna
name: Nilsson, Daniel
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 2: Figure S1. Flowchart showing different filtering steps of WGS SV analysis, Figure S2. Flowchart showing different filtering steps of WGS SNV analysis. Document S1. List of genes in the intellectual disability panel. Figure S3. Vcf2cytosure and array plots of illustrative cases. Figure S4. Breakpoint junction analysis of individuals RD_P77, RD_P393, RD_P400 and RD_P431. Document S2. Detailed clinical descriptions of individuals RD_P77, RD_P393, RD_P400 and RD_P431.
The Southwest: A Study of Regional Identity in Material Culture and Textual Sources during the Eastern Han Dynasty (25 - 220 C.E.)
Creators: name: Elias, Hajnalka Pejsue
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: Southwest
Eastern Han Dynasty
Material Culture
Regional Identity
Stelae

description: This dissertation studies examples of social and cultural memory and identity manifested in the art of the southwest, present-day Sichuan province, during the Eastern Han dynasty. Through the study of the southwest’s material culture, considered special for its distinct artistic style and content by scholars in the field of Chinese art, combined with analysis of early textual sources, it highlights a number of important findings associated with the region’s social make-up, economic activities, burial practices, education and governance, all of which contributed to the formation of a distinct regional identity. The southwest’s geographical isolation and its great distance from the Central Plains; the difficulties and dangers of road and river transport from all directions; its multi-ethnic make-up and the engrained cultural prejudice from the north, especially from the capital’s governing elite and literati, were all factors that contributed to a sense of regional separation that manifested itself in a distinct material culture and is hinted at in early textual sources. The main sources of material culture examined in the dissertation are pictorial brick tiles and stone reliefs discovered in stone and brick chamber tombs; decorated stone sarcophagi placed in the region’s cliff tombs; and commemorative and ancestral stelae erected for the governors of Shu and Ba commanderies. In its methodology, the dissertation employs Western theories on social and cultural memory and identity. It also bridges two fields of study, cultural and art history, which are often pursued separately due to their distinct specialisations. The dissertation’s findings aim to contribute to our knowledge of the southwest and to the study of regional identity in early imperial China.
Additional file 7: of Comparative transcriptomics identifies patterns of selection in roses
Creators: name: Li, Shubin
name: Zhong, Micai
name: Dong, Xue
name: Jiang, Xiaodong
name: Xu, Yuxing
name: Sun, Yibo
name: Cheng, Fang
name: Li, De-zhu
name: Tang, Kaixue
name: Wang, Siqing
name: Dai, Silan
name: Hu, Jin-Yong
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Figure S2. Phylogenetic clustering of the four species based on the 4447 Rosaceae-common transcripts. For each transcript, a Neighbor-Joining tree was constructed. The topologies in A, B, and C show the phylogenetic relationship supported by 65 and 33% (A), 0.7 and 0.4% (B), 0.5 and 0.5% (C) of transcripts. (PDF 34 kb)
Halo Models of Large Scale Structure
Creators: name: Cooray, Asantha
name: Sheth, Ravi
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We review the formalism and applications of the halo-based description of nonlinear gravitational clustering. In this approach, all mass is associated with virialized dark matter halos; models of the number and spatial distribution of the halos, and the distribution of dark matter within each halo, are used to provide estimates of how the statistical properties of large scale density and velocity fields evolve as a result of nonlinear gravitational clustering. We first describe the model, and demonstrate its accuracy by comparing its predictions with exact results from numerical simulations of nonlinear gravitational clustering. We then present several astrophysical applications of the halo model: these include models of the spatial distribution of galaxies, the nonlinear velocity, momentum and pressure fields, descriptions of weak gravitational lensing, and estimates of secondary contributions to temperature fluctuations in the cosmic microwave background.
description: 166 pages, 60 figures (low resolution in most color figures); Invited review article for Physics Reports (final version in press). Compact versions with two pages on one and full resolution figures are available from http://www.its.caltech.edu/~asante
Gnathoncus nannetensis
Creators: name: Penati, Fabio
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Histeridae
Gnathoncus
Gnathoncus nannetensis

description: 42. Gnathoncus nannetensis (Marseul)
 Literature data. “ Sardinia ” (Vienna 1980: 50; Audisio et al. 1995; Yélamos & Lackner 2004).
 Unpublished records. Nuoro prov.: Laconi, 19. V.1967, 1 ex (DPPS).
 Chorotype. 1.02 PAL (Palearctic).
 Italian distribution. Piedmont, Lombardy, Trentino-Alto Adige, Venetia, Friuli-Venezia Giulia, Liguria, Emilia-Romagna, Tuscany, Marches, Abruzzi, Latium, Basilicata, Calabria and Sardinia.
 Ecology. Occurs in any type of decaying organic matter (excrements, carcasses, rotting fungi and vegetables, foodstuffs, hen houses and granaries), but according to Yélamos (2002) it is especially abundant on bat guano accumulated close to the entrance of caves and in the nests of many bird species.
 Notes. Penati and Vienna (2002) considered this species, previously recorded only in the regional distribution table of Italian histerids (Vienna 1980), as absent from Sardinia, due to the lack of Sardinian specimens in the numerous collections examined. The specimens preserved in the DPPS collections and determined by P. Vienna confirm the correctness of the previous record and the presence of the species on the island.
description: Published as part of Penati, Fabio, 2009, An updated catalogue of the Histeridae (Coleoptera) of Sardinia, with faunistic, zoogeographical, ecological and conservation remarks *, pp. 197-280 in Zootaxa 2318 on page 236
title: Conférence de Jean-Baptiste Gourinat  [ "Comme des sceaux imprimés dans la cire" : l’empreinte de Platon sur la théorie stoïcienne de la connaissance ] direct
Publisher: name: Centre Jean Pépin  UMR 8230 ENS Paris-CNRS-PSL
Year: 2024

description: [ "Comme des sceaux imprimés dans la cire" : l’empreinte de Platon sur la théorie stoïcienne de la connaissance ]
Peak-effect and surface crystal-glass transition for surface-pinned vortex array
Creators: name: Placais, B.
name: Lutke-Entrup, N.
name: Bellessa, J.
name: Mathieu, P.
name: Simon, Y.
name: Sonin, E. B.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: The peak effect has been investigated in clean Nb crystals with artificially corrugated surfaces by measuring the linear surface impedance in the 1kHz-1MHz frequency range. From a two-mode analysis of the complex spectra, we establish that vortex dynamics is governed by surface pinning and deduce the associated vortex slippage length. We demonstrate experimentally and theoretically that the peak effect is related to a transition from collective to individual surface pinning. A proper account of the peak-effect anomalies implies softening of the shear rigidity by disorder-induced lattice deformations. This leads to a vortex crystal-glass transition induced by surface defects.
description: 12 pages, 2 figures
MOESM5 of GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients
Creators: name: Neckmann, Ulrike
name: Wolowczyk, Camilla
name: Hall, Martina
name: Almaas, Eivind
name: Ren, Jiang
name: Zhao, Sen
name: Johannessen, Bjarne
name: Skotheim, Rolf
name: BjĂ¸RkĂ¸Y, Geir
name: Dijke, Peter
name: Holien, Toril
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 5:Â Table S3. Relationship between gene expression of BMP-antagonists and RFS in breast cancer patients. High and low expression were defined as above (HR > 1.2, p-value < 0.05) and below (HR < 0.83, p-value < 0.05) median.
Empirical Analysis of the Typical Breeding Pattern of Clam in Hongdao Town and the Preliminary Estimates of Costs and Benefits
Creators: name: YANG, Xijuan
name: ZHANG, Shijun
name: YANG, Xijuan
name: ZHANG, Shijun
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Hongdao clam
subject: Breeding pattern
subject: Cost-benefit analysis

description: Based on the survey data about clam breeding farmers in Hongdao Town in August 2011, this paper analyzes the production and operation of typical clam breeding pattern, and estimates the costs and benefits. Through the analysis of operation conditions and economic conditions of Hongdao clam breeding, this paper aims to explore a more reasonable and effective breeding pattern so as to reduce breeding costs and market risks, and increase breeding farmers' income.
Sensitivity of the Prime-Cam Instrument on the CCAT-prime Telescope
Creators: name: Choi, Steve K.
name: Austermann, Jason
name: Basu, Kaustuv
name: Battaglia, Nicholas
name: Bertoldi, Frank
name: Chung, Dongwoo T.
name: Cothard, Nicholas F.
name: Duff, Shannon
name: Duell, Cody J.
name: Gallardo, Patricio A.
name: Gao, Jiansong
name: Herter, Terry
name: Hubmayr, Johannes
name: Niemack, Michael D.
name: Nikola, Thomas
name: Riechers, Dominik
name: Rossi, Kayla
name: Stacey, Gordon J.
name: Stevens, Jason R.
name: Vavagiakis, Eve M.
name: Vissers, Michael
name: Walker, Samantha
Publisher: name: arXiv
Year: 2019
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: CCAT-prime is a new 6 m crossed Dragone telescope designed to characterize the Cosmic Microwave Background (CMB) polarization and foregrounds, measure the Sunyaev-Zel'dovich effects of galaxy clusters, map the [CII] emission intensity from the Epoch of Reionization (EoR), and monitor accretion luminosity over multi-year timescales of hundreds of protostars in the Milky Way. CCAT-prime will make observations from a 5,600 m altitude site on Cerro Chajnantor in the Atacama Desert of northern Chile. The novel optical design of the telescope combined with high surface accuracy ($
description: Version accepted for publication by Journal of Low Temperature Physics; updates on FPI detectors, more details given on sensitivity calculations
MOESM3 of GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients
Creators: name: Neckmann, Ulrike
name: Wolowczyk, Camilla
name: Hall, Martina
name: Almaas, Eivind
name: Ren, Jiang
name: Zhao, Sen
name: Johannessen, Bjarne
name: Skotheim, Rolf
name: BjĂ¸RkĂ¸Y, Geir
name: Dijke, Peter
name: Holien, Toril
Publisher: name: figshare
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 3:Â Table S1. Genes encoding secreted proteins that are significantly upregulated in 66cl4 and their prognostic value in breast cancer patients. High and low expression were defined as above (HR > 1.2, p-value < 0.05) and below (HR < 0.83, p-value < 0.05) median.
MOESM5 of GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients
Creators: name: Neckmann, Ulrike
name: Wolowczyk, Camilla
name: Hall, Martina
name: Almaas, Eivind
name: Ren, Jiang
name: Zhao, Sen
name: Johannessen, Bjarne
name: Skotheim, Rolf
name: Bjørkøy, Geir
name: Dijke, Peter Ten
name: Holien, Toril
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 5: Table S3. Relationship between gene expression of BMP-antagonists and RFS in breast cancer patients. High and low expression were defined as above (HR > 1.2, p-value < 0.05) and below (HR < 0.83, p-value < 0.05) median.
Saprinus (Saprinus) calatravensis Fuente 1899
Creators: name: Penati, Fabio
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Histeridae
Saprinus
Saprinus calatravensis

description: 47. Saprinus (Saprinus) calatravensis Fuente
 Literature data. “Sardinia” (Yélamos & Lackner 2004). Cagliari prov.: Flumentorgiu, VI.1895, FS, 1 ex (Penati & Vienna 2002). Nuoro prov.: Nurri, loc. Padenti [= Padonti-Nurri], 14.VIII.1941, ES, 6 ex (Penati & Vienna 2002). Sassari prov.: Isola Rossa, 20.VI.1995, RPa, 1 ex (CRPa).
 Chorotype. 1.08 CAM (Centralasiatic-Mediterranean).
 Italian distribution. Piedmont, Venetia, Liguria, Tuscany, Umbria, Marches, Latium, Campania, Abruzzi, Apulia, Basilicata, Calabria, Sicily and Sardinia.
 Ecology. Shows the same characteristics as its congeners.
 Notes. Due to the scarce morphological differentiation between them, Saprinus calatravensis, S. chalcites (Illiger) and S. georgicus Marseul constitute a group of species difficult to identify without study of the aedeagus, and which have often been confused in the past. Therefore, data referring to a few isolated females of doubtful identity, deposited in some of the studied collections (for example CCMe), were not included in the present list. The exact Sardinian distribution of these three species can only be assessed after a careful and thorough revision of the specimens from the various collections and extensive field campaigns.
description: Published as part of Penati, Fabio, 2009, An updated catalogue of the Histeridae (Coleoptera) of Sardinia, with faunistic, zoogeographical, ecological and conservation remarks *, pp. 197-280 in Zootaxa 2318 on page 238
Additional file 1 of Examining COVID-19 vaccine uptake and attitudes among 2SLGBTQ+ youth experiencing homelessness
Creators: name: Abramovich, Alex
name: Pang, Nelson
name: Kunasekaran, Sharumathy
name: Moss, Amanda
name: Kiran, Tara
name: Pinto, Andrew D.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1. Key Survey Measures.
Evaluation of the Overall Level of New Urbanization in Hebei Province Based on Factor Analysis and GIS
Creators: name: ZHAO, Shuqin
name: SHI, Xuemeng
name: NIU, Yunfan
name: ZHAO, Shuqin
name: SHI, Xuemeng
name: NIU, Yunfan
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: New urbanization
subject: Factor analysis
subject: GIS
subject: Hebei province

description: Urbanization is the result of economic and social development, but also an important indicator to measure the level of regional economic and social development. Since the reform and opening up, the level of urbanization in Hebei province has been lagging behind the national average level. The 18th National Congress of the CPC proposed to develop new urbanization, and this paper evaluated the comprehensive urbanization level of Hebei province combined with new connotation of urbanization. It constructed an evaluation index system of Hebei Province’s urbanization comprehensive level, and then used the method of factor analysis with SPSS statistical analysis software to distinguish the major influencing factors. Thirdly, it overlaid the result with spatial pattern, which calculated by the spatial visualization function of ArcGIS software, making the evaluation results presented in a more vivid way. Finally, it analyzed the driving factors of urbanization development in Hebei Province and put forward some suggestions.
Critical behaviour of the Ginzburg-Landau model in the type II region
Creators: name: Kajantie, K.
name: Laine, M.
name: Neuhaus, T.
name: Rajantie, A.
name: Rummukainen, K.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We study the critical behaviour of the three-dimensional U(1) gauge+Higgs theory (Ginzburg-Landau model) at large scalar self-coupling λ(``type II region'') by measuring various correlation lengths as well as the Abrikosov-Nielsen-Olesen vortex tension. We identify different scaling regions as the transition is approached from below, and carry out detailed comparisons with the criticality of the 3d O(2) symmetric scalar theory.
description: Lattice2001(higgssusy), 3 pages
MOESM1 of Fast quantitative urinary proteomic profiling workflow for biomarker discovery in kidney cancer
Creators: name: Lin, Lin
name: Yu, Quan
name: Zheng, Jiaxin
name: Cai, Zonglong
name: Tian, Ruijun
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology

description: Additional file 1: Table S1. Clinical information of the KC patients.
MOESM3 of GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients
Creators: name: Neckmann, Ulrike
name: Wolowczyk, Camilla
name: Hall, Martina
name: Almaas, Eivind
name: Ren, Jiang
name: Zhao, Sen
name: Johannessen, Bjarne
name: Skotheim, Rolf
name: Bjørkøy, Geir
name: Dijke, Peter Ten
name: Holien, Toril
Publisher: name: figshare
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 3: Table S1. Genes encoding secreted proteins that are significantly upregulated in 66cl4 and their prognostic value in breast cancer patients. High and low expression were defined as above (HR > 1.2, p-value < 0.05) and below (HR < 0.83, p-value < 0.05) median.
Fragment-based approaches to targeting EthR from mycobacterium tuberculosis
Creators: name: McConnell, Brendan Neil
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: EthR
tuberculosis
ethionamide
TB
fragment-based drug design
FBDD
fragment-based ligand design
FBLD
isothermal titration calorimetry
ITC
thermal shift
differential scanning fluorimetry
DSF
surface plasmon resonance
SPR
sulfone
piperazine

description: Tuberculosis affects millions of people worldwide every year. The current treatment for TB is divided into a regimen of both first- and second-line drugs, where first-line treatments are more tolerated and require shorter treatment lengths. With rising levels of resistance, alternative treatment regimes are urgently needed to fight this disease. Ethionamide, a second-line drug is administered as a prodrug which is activated in vivo by the enzyme EthA, which is in turn regulated by EthR. The disruption of the action of EthR could lead to novel therapeutics which could enhance the efficacy of ethionamide, and raise it to a first-line treatment. The work reported in this thesis examines the elaboration of three chemical scaffolds using fragment-based approaches to develop novel inhibitors capable of disrupting the EthR-DNA interaction. The first scaffold, 5-(furan-2-yl)isoxazole was investigated by fragment-merging approaches and produced compounds with the best of these having a KD of 7.4 uM. The second scaffold, an aryl sulfone was elaborated using fragment-merging strategies. This led to several modifications of the fragment, leading to several variants with KDs around 20 uM. With both of these series the affinity could not be improved below 10 uM and due to the synthetic complexity a further scaffold was prioritised. The third scaffold was explored was a 4-(4-(trifluoromethyl)phenyl)piperazine using fragmentgrowing from the NH of the piperazine to probe deeper into the EthR binding pocket. In addition to this, SAR around the 4-(trifluoromethyl)phenyl group was assessed to explore the interactions with EthR. These modifications led to compounds with nanomolar IC50s. A range of compounds were then screened by REMAssay to determine the boosting effect on ethionamide, and this identified compounds with up to 30 times boosting in the ethionamide MIC. The final chapter examines a concept where compounds were designed to exploit the dimeric nature of EthR by linking two chemical warheads with a flexible linker. These compounds are examined using mass spectrometry to investigate the stoichiometry of the interaction to provide insight into the binding of these extended compounds and exploring an alternative strategy to inhibit EthR. The work in this thesis demonstrated the successful use of fragment-based approaches for development of novel EthR inhibitors which showed significant ethionamide boosting effects.
description: Cambridge Commonwealth, European and International Trust (Poynton Cambridge Australia Scholarship) Cambridge Philosophical Society Access to Learning Fund
Additional file 1 of Association between COVID-19 vaccine hesitancy and generalized trust, depression, generalized anxiety, and fear of COVID-19
Creators: name: Sekizawa, Yoichi
name: Hashimoto, Sora
name: Denda, Kenzo
name: Ochi, Sae
name: So, Mirai
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Supplementary Table 1. Results of the Fully Adjusted Multinomial Logistic Regression Analyses at wave 3.
The Strategy for the Development of Low-carbon Animal Husbandry in Taiwan and the Lessons Drawn from It
Creators: name: CHEN, Tian
name: XIAO, Haifeng
name: CHEN, Tian
name: XIAO, Haifeng
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Low carbon
subject: Animal husbandry
subject: Energy conservation and emission reduction
subject: Taiwan

description: In this paper, we analyze the strategies for the development of low-carbon animal husbandry in Taiwan which mainly focuses on strengthening the livestock farm carbon reduction, promoting the livestock breeding energy conservation and emission reduction technology, and develop the environmental protection laws related to animal husbandry to combat animal husbandry pollution. Learning from the strategies and legislative management experience for the development of low-carbon animal husbandry in Taiwan, we set forth the following recommendations for improving the development of low-carbon animal husbandry in mainland China: increasing the financial investment in environmental protection; strengthening the scientific research of cleaner production; promoting sound pollution control legislation; moderately restricting the scale of livestock and poultry farm.
Nucleon momentum distribution in deuteron and other nuclei within the light-front dynamics method
Creators: name: Antonov, A. N.
name: Gaidarov, M.
name: Ivanov, M. V.
name: Kadrev, D. N.
name: Krumova, G. Z.
name: Hodgson, P. E.
name: von Geramb, H. V.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The relativistic light-front dynamics (LFD) method has been shown to give a correct description of the most recent data for the deuteron monopole and quadrupole charge form factors obtained at the Jefferson Laboratory for elastic electron-deuteron scattering for six values of the squared momentum transfer between 0.66 and 1.7 (GeV/c)$^{2}$. The good agreement with the data is in contrast with the results of the existing non-relativistic approaches. In this work we firstly make a complementary test of the LFD applying it to calculate another important characteristic, the nucleon momentum distribution $n(q)$ of the deuteron using six invariant functions $f_{i}$ $(i=1,...,6)$ instead of two ($S$- and $D$-waves) in the nonrelativistic case. The comparison with the $y$-scaling data shows the decisive role of the function $f_{5}$ which at $q\geq$ 500 MeV/c exceeds all other $f$-functions (as well as the $S$- and $D$-waves) for the correct description of $n(q)$ of the deuteron in the high-momentum region. Comparison with other calculations using $S$- and $D$-waves corresponding to various nucleon-nucleon potentials is made. Secondly, using clear indications that the high-momentum components of $n(q)$ in heavier nuclei are related to those in the deuteron, we develop an approach within the natural orbital representation to calculate $n(q)$ in $(A,Z)$-nuclei on the basis of the deuteron momentum distribution. As examples, $n(q)$ in $^{4}$He, $^{12}$C and $^{56}$Fe are calculated and good agreement with the $y$-scaling data is obtained.
description: 16 pages, 6 figures, corrected, to appear in Phys. Rev. C in February 2002
Projected self: the de se across dimensions and beyond pronouns
Creators: name: Christofaki, Rodanthi
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: de se
self-reference
expressives
expressive meaning
use-conditional meaning
Japanese
presupposition
conventional implicature
semantics
pragmatics
indexicals
indexicality
names
1st person pronoun
self
first person

description: This dissertation is about how attitudes de se are encoded in content outside the assertive domain, as well as by expressions which are not really pronouns, such as nouns. First of all, it provides evidence that expressives are necessarily de se, which means that non-pronominal expressions, such as nouns, verbs etc. can be de se in a non-assertive dimension. Next, it examines in full detail the landscape of expressive (or as it is more recently known, use-conditional) meaning and the extant dedicated frameworks, arguing that they are misguided, due to conceptual issues and not being restrictive enough to be theoretically meaningful. I then move to the debate of whether expressives are presuppositions or a distinct kind of meaning, arguing for a conciliatory solution which proposes that expressives are ordinary presuppositions endowed with a compositionally irrelevant, indexical kind of meaning which I call ‘associative’. This solution explains the ambivalent behaviour of expressives, i.e. that they may display filterability and non-displaceability simultaneously. The next topic is that of self-reference of Japanese, a language which lacks genuine personal pronouns and where speakers may use a multitude of expressions instead for this function: a long list of so-called personal pronouns which are actually nouns, then also common nouns and proper names. After a thorough description of the data, I offer a formal account of self-reference in Japanese, accommodating all the different kinds of expressions used. The main theoretical implication of this account is that the absolute distinction between indexicals and names is denied, as names in Japanese can encode the de se. Moreover, it is shown that Japanese so-called 1st person pronouns are de se in both dimensions, as they are used as self-referring expressions but they are also endowed with associative meaning.
description: PhD funded by the Leverhulme Foundation (Grant ID/Ref: RPG-2014-017)
Molecular and DNA Artificial Neural Networks via Fractional Coding
Creators: name: Liu, Xingyi
name: Parhi, Keshab K.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Emerging Technologies (cs.ET)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: This paper considers implementation of artificial neural networks (ANNs) using molecular computing and DNA based on fractional coding. Prior work had addressed molecular two-layer ANNs with binary inputs and arbitrary weights. In prior work using fractional coding, a simple molecular perceptron that computes sigmoid of scaled weighted sum of the inputs was presented where the inputs and the weights lie between [-1, 1]. Even for computing the perceptron, the prior approach suffers from two major limitations. First, it cannot compute the sigmoid of the weighted sum, but only the sigmoid of the scaled weighted sum. Second, many machine learning applications require the coefficients to be arbitrarily positive and negative numbers that are not bounded between [-1, 1]; such numbers cannot be handled by the prior perceptron using fractional coding. This paper makes four contributions. First molecular perceptrons that can handle arbitrary weights and can compute sigmoid of the weighted sums are presented. Thus, these molecular perceptrons are ideal for regression applications and multi-layer ANNs. A new molecular divider is introduced and is used to compute sigmoid(ax) where a > 1. Second, based on fractional coding, a molecular artificial neural network (ANN) with one hidden layer is presented. Third, a trained ANN classifier with one hidden layer from seizure prediction application from electroencephalogram is mapped to molecular reactions and DNA and their performances are presented. Fourth, molecular activation functions for rectified linear unit (ReLU) and softmax are also presented.
description: IEEE Transactions on Biomedical Circuits and Systems, 2020
Sustainability standards, gender, and nutrition among smallholder farmers in Uganda
Creators: name: Chiputwa, Brian
name: Qaim, Matin
name: Chiputwa, Brian
name: Qaim, Matin
Publisher: name: Unknown
Year: 2014
Subjects: subject: Community/Rural/Urban Development
subject: Consumer/Household Economics
subject: Food Consumption/Nutrition/Food Safety
subject: Food Security and Poverty
subject: International Development
subject: private standards
subject: smallholder farmers
subject: nutrition impact
subject: gender
subject: Uganda

description: Sustainability standards are gaining in importance in global markets for high-value foods. While previous research has shown that participating farmers in developing countries may benefit through income gains, nutrition impacts have hardly been analysed. We use survey data from smallholder coffee farmers in Uganda – certified under Fairtrade, Organic, and UTZ – to analyse impacts on food security and dietary quality. Estimates of instrumental variable models and simultaneous equation systems show that certification increases calorie and micronutrient consumption, mainly through higher incomes and improved gender equity. In certified households, women have greater control of coffee production and monetary revenues from sales.