cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: A modified Simon-Lieb inequality in the modified XY modeI
Creators: name: Plaga, Fabio Adrian
Year: 2024

description: Simon, Lieb und Rivasseau zeigten in [17], [11] and [16] erstmals die Simon-Lieb Ungleichung, eine Korrelationsungleichung im Ising und XY Modell. Der erste Teil dieser Arbeit bespricht drei verschiedene Ansätze diese Ungleichung im XY Modell zu beweisen. Der erste Ansatz befasst sich mit dem ursprünglichen Beweis, welcher die Parserval’sche Gleichung benutzt. Der zweite Ansatz benutzt das Konzept der gefärbten Schleifenkonfigurationen, eingeführt von van Engelenburg und Lis [19], während der dritte Ansatz von der zufälligen Irrfahrtszerlegung von Brydges, Fröhlich und Spencer [2] Gebrauch macht. Im zweiten Teil der Arbeit untersuchen wir ein modifiziertes XY Modell, in welchem die Spins ferromagnetisch und nematisch interagieren, und zeigen eine abgeschwächte Version der Simon-Lieb Ungleichung im modifizierten XY Modell. Mit dieser Ungleichung folgern wir eine untere Schranke der kritischen inversen Temperatur. Als ein Nebenprodukt dieser Ausführungen beweisen wir eine neue Korrelationsungleichung im modifizierten XY Modell indem wir eine Einzelzufallsstromzerlegung, ähnlich zu der von [19], einführen.
description: Simon, Lieb and Rivasseau proved the Simon-Lieb inequality, a correlation inequality in the Ising and XY model, in [17], [11] and [16]. The first part of the thesis is mainly expository and discusses three different approaches to prove the Simon-Lieb inequality in the XY model. The first one treats the original proof using Parseval’s identity, while the second one uses coloured loop configurations introduced by van Engelenburg and Lis [19] while the third one uses the random walk expansion introduced by Brydges, Fröhlich and Spencer [2]. In the second part of the thesis we prove a modified Simon-Lieb inequality in a modified XY model, where the spins interact both ferromagnetically and nematically. The inequality is sufficiently strong to follow a lower bound on the critical inverse temperature. As a by-product of the modified Simon-Lieb inequality a new correlation inequality in the modified XY model is derived by introducing a single random current expansion similar to the one in [19].
Silver Nanoparticle Controlled Synthesis and Implications in Spectroscopy, Biomedical and Optoelectronics Applications
Creators: name: Stamplecoskie, Kevin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Photochemistry
Silver Nanoparticles
Plasmon Absorption

description: This thesis describes the photochemical synthesis of silver nano particles, several ways to make these particles as well as control the size and shape of the colloidal particles. Understanding the primary reactions in photochemical nanoparticle formation has lead to important contributions to the overall mechanism of metal nanoparticle synthesis. The size and shape control of the particles is shown to have important implications for the Raman spectrum of surface bound molecules. The particles have also been used in antibacterial properties where it was shown that silver nanoparticles are more antibacterial than the corresponding silver cation, while remaining non-toxic to several common cell lines. The particles were also shown to have some interesting properties that can be exploited in lithography and optoelectronics.
Interactive System for Scientific Publication Visualization and Similarity Measurement based on Citation Network
Creators: name: Alfraidi, Hanadi Humoud A
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Information Visualization
Citation Network
Similarity Measures
Document Similarity

description: Online scientific publications are becoming more and more popular. The number of publications we can access almost instantaneously is rapidly increasing. This makes it more challenging for researchers to pursue a topic, review literature, track research history or follow research trends. Using online resources such as search engines and digital libraries is helpful to find scientific publications, however most of the time the user ends up with an overwhelming amount of linear results to go through. This thesis proposes an alternative system, which takes advantage of citation/reference relations between publications. This demonstrates better insight of the hierarchy distribution of publications around a given topic. We also utilize information visualization techniques to represent the publications as a network. Our system is designed to automatically retrieve publications from Google Scholar and visualize them as a 2-dimensional graph representation using the citation relations. In this, the nodes represent the documents while the links represent the citation/reference relations between them. Our visualization system provides a better view of publications, making it easier to identify the research flow, connect publications, and assess similarities/differences between them. It is an interactive web based system, which allows the users to get more information about any selected publication and calculate a similarity score between two selected publications. Traditionally, similar documents are found using Natural Language Processing (NLP), which compares documents based on matching their contents. In the proposed method, similar documents are found using the citation/reference relations which are iii represented by the relationship that was originally inputted by the authors. We propose a new path based metric for measuring the similarity scores between any pair of publications. This is based on both the number of paths and the length of each path. More paths and shorter lengths increase the similarity score. We compare our similarity score results with another similarity score from Scurtu’s Document Similarity [1] that uses the NLP method. We then use the average of the similarity scores collected from 15 users as a ground truth to validate the efficiency of our method. The results indicate that our Citation Network approach yielded better scores than Scurtu’s approach.
The Oxidative Stress Defenses of Campylobacter jejuni
Creators: name: Flint, Annika
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Campylobacter jejuni
Oxidative stress defense
Catalase
Hemin trafficking

description: Campylobacter jejuni infection is one of the leading causes of gastroenteritis in humans worldwide. During colonization of the gastrointestinal tract, C. jejuni will be unavoidably exposed to reactive oxygen species (ROS) produced by the host immune system and other intestinal microbiota. Identification of defenses against ROS is therefore important for understanding how Campylobacter survives this environmental stress during infection. Construction of isogenic deletion mutants into genes encoding potential oxidative stress defense systems followed by phenotypic screening revealed genes important for oxidant defense within C. jejuni. Surprisingly, genes involved in motility were found to play an indirect role in resistance to oxidative stress. Deletion of the flagellar motor apparatus genes, motAB, resulted in increased sensitivity towards superoxide which could be restored by fumarate supplementation or tandem deletion of motAB with ccoQ (cytochrome c oxidase). This finding suggested that disruption of the proton gradient across the inner membrane resulted in increased superoxide production in non-motile flagellar mutants. Phenotypic screening of the mutant library also identified a novel gene (cj1386) specifically involved in hydrogen peroxide defense within the cell. Hydrogen peroxide detoxification within living organisms is predominantly carried out by catalase enzymes. Interestingly, cj1386 is located directly downstream from katA (catalase) in the C. jejuni genome and it was found that a ∆cj1386 mutant had reduced catalase activity relative to wild-type C. jejuni. Immunoprecipitation of KatA from ∆cj1386 revealed a significant reduction in hemin content associated with KatA suggesting a role for cj1386 in hemin trafficking to KatA. Hemin binding experiments with purified Cj1386 demonstrated the ability of Cj1386 to bind hemin with a 1:1 hemin-to-protein binding ratio. Furthermore, co-immunoprecipitation experiments revealed an interaction between KatA and Cj1386. Mutagenesis of conserved amino acids in Cj1386 demonstrated that tyrosine 57 plays an important role in hemin affinity and is required for proper hemin content of KatA within the cell. Overall, this work provides a global characterization of key oxidant defenses within C. jejuni and provides one of the first studies investigating hemin trafficking to KatA.
Identification of Risk Factors Associated with Aetiology of Amyotrophic Lateral Sclerosis Based on Systematic Review and Meta-Analysis
Creators: name: Wang, Ming-Dong
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Amyotrophic lateral sclerosis
Motor neuron disease
Risk factor
Heavy metal
Pesticide
Trauma
Injury
Solvent
Electric shock
Smoking
Ataxin-2
Systematic review
Meta-analysis
Genetic factor
Progression
Aetiology

description: To identify the risk factors being associated with aetiology of amyotrophic lateral sclerosis (ALS), a series of systematic reviews based on existing observational epidemiological studies identified through searching of bibliographic databases were conducted. Associations between ALS and a number of genetic and environmental risk factors were examined using meta-analysis. Specifically we found that previous exposure to lead, pesticides, solvents, experience of trauma and electric shock were associated with relative increased risks of developing ALS of 86% [odds ratio (OR) =1.86, 95% CI: 1.39-2.48], 57% (OR=1.57,95% CI: 1.19-2.08), 47% (OR=1.47, 95%CI: 1.13-1.80), 64% (OR=1.64; 95%CI: 1.36-1.98), and 2.27% (OR=3.27, 95%CI:1.87-5.73) respectively, compared to their corresponding controls. The presence of intermediate CAG repeat expansion in the ATXN2 gene was associated with a 4.4 -fold increase in the risk of ALS (OR=4.44, 95%CI: 2.91-6.76). However, the attributable risk associated with each identified risk factor was estimated to be less than 5% of all ALS cases. These results confirm that ALS is a rare multifactorial degenerative condition of motor-neurons.
The COSMIC Bubble Helmet : A Non-Invasive Positive Pressure Ventilation System for COVID-19
Creators: name: Gusti, Vionarica
name: Wu, Wan Jun
name: Grover, Arpan
name: Chiu, Sabian
name: Su, Kai-Wen
name: Ma, Erica
name: Chow, Chanelle K.
name: Sit, Ella
name: Lim, Jun
name: Pandhari, Abhijit
name: Park, Mattias
name: Lee, Ryan
name: Shahril, Faisal
name: Lim, Shawn T.
name: Nguan, Christopher Y.
name: Driedger, Dan
name: Sinha, Avinash K.
name: Scrooby, Ivan G.
name: Mclean, Neilson J.
name: Lee, Michael W.
name: Yan, Tyler D.
name: Team, The COSMIC
Publisher: name: Institute of Electrical and Electronics Engineers
Year: 2021

description: COSMIC Medical, a Vancouver-based open-source volunteer initiative, has designed an accessible, affordable, and aerosol-confining non-invasive positive-pressure ventilator (NIPPV) device, known as the COSMIC Bubble Helmet (CBH). This device is intended for COVID-19 patients with mild-to-moderate acute respiratory distress syndrome. System Design: CBH is composed of thermoplastic polyurethane, which creates a flexible neck seal and transparent hood. This device can be connected to wall oxygen, NIPPVs including Continuous Positive Airway Pressure and Bi-level Positive Airway Pressure, and mechanical ventilators. Discussion: Justification of CBH design components relied on several factors, predominantly the safety and comfort of patients and healthcare providers. Conclusion: CBH has implications within and outside of the pandemic, as an alternative to invasive mechanical ventilation methods. We have experimentally verified that CBH is effective in minimizing aerosolization risks and performs at specified clinical requirements.
The Characterization of the Molecular Structure and the Partners of MLIP
Creators: name: Saleh, Fawaz
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015

description: A novel gene, Muscle-enriched A-type Lamin-Interacting Protein (MLIP), was identified in our lab through a yeast two-hybrid screen using Lamin A/C N-terminal sequence as bait (10-230 amino acids), in an attempt to shed light on the complex nature of laminopathies. MLIP is a non-homologous, single copy gene conserved in amniotes. MLIP’s expression differs between tissues and is subjected to extensive tissue-dependent alternative splicing. Some of MLIP’s isoforms, lacking specific exons, have been identified and referred to as MLIP Δ2, Δ3, Δ4, Δ6, Δ8 and Δ10. The putative Lamin binding domain was identified to be within the first 41 amino acids of MLIP, spanning across exon 1 and 2 of the MLIP gene. MLIP’s Molecular function remains largely unknown. The main objective of this study is to map the exact location of MLIP:Lamin A/C binding domain and the identification of MLIP isoform specific binding partners in different tissues. We hypothesized that the MLIP:Lamin binding domain is specific interaction and is located on the protein encoded by exon 1. We also hypothesized that the phenotypic observations in laminopathies may be in part due to the differential MLIP isoform expression in different tissue, whereas MLIP isoforms have different binding partners in different tissues resulting in variable functions. Our results demonstrate that MLIP is a spliced protein that contains alternative promoters that are tissue specific, which we annotated as MLIP-1a and 1b. The MLIP alternative promoters are located on the 5’ end of the MLIP gene and contain an alternative start site situated on exon 3. We also found that MLIP-1a splice variants are predominantly expressed in the heart and skeletal muscle, whereas MLIP-1b splice variants are expressed in almost all tissue types studied. In addition, hMLIP binds to Lamin A/C and the hMLIP-Lamin binding domain is exclusively specific to the protein encoded in exon-1a of the MLIP gene. Moreover, MLIP and it’s splice variants (1a and 1b) show high levels of expression in the early post-natal heart which decrease with age, mimicking the expression of Lamin A/C. This gives us a good indication that MLIP:Lamin A/C interaction plays a vital role in heart development and mutations in that part of the gene might contribute to laminopathies pathology.
Supplementary document for Utilizing thermally-induced selective mode shaping for high extinction ratio in-line fiber modulator/polarizer - 5422877.pdf
Creators: name: Heidari, Mohsen
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplementary Document: Utilizing thermally-induced selective mode shaping for high extinction ratio in-line fiber modulator/polarizer
PKA Signaling in ABCA1 Function: A Role in Modulation of Cholesterol Efflux and Macrophage Inflammation
Creators: name: Ma, Loretta T. K.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: ABCA1
PKA
cholesterol
anti-inflammatory
macrophage
IL-10
A-kinase anchoring protein

description: Formation of lipid-laden macrophage foam cells and inflammation are the central components in the initiation and progression of atherosclerosis. ABCA1 is well established as an anti-atherogenic factor that facilitates cellular cholesterol and phospholipid efflux, promotes reverse cholesterol transport, and suppresses pro-inflammatory cytokine secretion. Through these functions, ABCA1 is capable of reducing the lipid burden in atherosclerotic plaque. PKA signaling is an integral factor in promoting many anti-atherogenic functions of ABCA1; however, mechanistic aspects of PKA signaling associated with ABCA1 remain poorly defined. Thus, the first part of this study investigates the involvement of spatially regulated PKA signaling in ABCA1 activities through the use of st-Ht31, a PKA de-anchoring peptide. It appears that de-anchoring PKA robustly increases ABCA1-mediated microparticle release, one of the cholesterol efflux pathways of ABCA1, and reverses macrophage foam cell formation. These results highlight the significance of subcellular compartmentalization of PKA signaling in ABCA1 functions and present PKA de-anchoring as a potential therapeutic strategy for atherosclerotic lesion regression. The second part of this study provides evidence that ABCA1 activates PKA and promotes the secretion of anti-inflammatory IL-10, a cytokine crucial for inflammation resolution. Furthermore, we provide evidence that this elevated PKA activity is the underlying mechanism in which macrophage ABCA1 promotes M2-like inflammatory response. Our results also suggest that ABCA1 activates PKA by regulating cholesterol, which poises macrophages towards an anti-inflammatory or M2-activated phenotype. Collectively, we demonstrate that PKA signaling plays a crucial multifactorial role in anti-atherogenic functions of ABCA1.
ОБРАЗЫ И СИМВОЛЫ МАГИЧЕСКОГО РЕАЛИЗМА В СОВРЕМЕННЫХ ЛИТЕРАТУРНЫХ ПРОИЗВЕДЕНИЯХ: АНАЛИЗ И ИНТЕРПРЕТАЦИЯ.
Creators: name: Каримов, Зиёахмад
Publisher: name: Zenodo
Year: 2025

description: Магический реализм, зародившийся как художественный метод в середине XX века, сохраняет свою актуальность в современной литературе, трансформируясь в ответ на вызовы глобализации, цифровизации и экологического кризиса. Его ключевая особенность — синтез реального и иррационального — позволяет авторам создавать многомерные нарративы, где фантастическое не противоречит действительности, а становится её неотъемлемой частью. В условиях современности магический реализм обретает новое звучание, выступая инструментом для репрезентации сложных социальных, экзистенциальных и культурных феноменов через систему образов и символов.
REACT 2024: the Second Multiple Appropriate Facial Reaction Generation Challenge.
Creators: name: Song, Siyang
name: Spitale, Micol
name: Luo, Cheng
name: Palmero, Cristina
name: Barquero, Germán
name: Zhu, Hengde
name: Escalera, Sergio
name: Valstar, Michel F
name: Baur, Tobias
name: Ringeval, Fabien
name: André, Elisabeth
name: Gunes, Hatice
Publisher: name: IEEE
Year: 2024

description: In dyadic interactions, humans communicate their intentions and state of mind using verbal and non-verbal cues, where multiple different facial reactions might be appropriate in response to a specific speaker behaviour. Then, how to develop a machine learning (ML) model that can automatically generate multiple appropriate, diverse, realistic and synchronised human facial reactions from an previously unseen speaker behaviour is a challenging task. Following the successful organisation of the first REACT challenge (REACT 2023), this edition of the challenge (REACT 2024) employs a subset used by the previous challenge, which contains segmented 30-secs dyadic interaction clips originally recorded as part of the NOXI and RECOLA datasets, encouraging participants to develop and benchmark Machine Learning (ML) models that can generate multiple appropriate facial reactions (including facial image sequences and their attributes) given an input conversational partner's stimulus under various dyadic video conference scenarios. This paper presents: (i) the guidelines of the REACT 2024 challenge; (ii) the dataset utilized in the challenge; and (iii) the performance of the baseline systems on the two proposed sub-challenges: Offline Multiple Appropriate Facial Reaction Generation and Online Multiple Appropriate Facial Reaction Generation, respectively. The challenge baseline code is publicly available at https://github.com/reactmultimodalchallenge/baseline_react2024.
Multi-modal Human Behaviour Graph Representation Learning for Automatic Depression Assessment.
Creators: name: Shen, Haotian
name: Song, Siyang
name: Gunes, Hatice
Publisher: name: IEEE
Year: 2024

description: Automatic depression assessment (ADA) often relies on crucial cues embedded in human verbal and non-verbal behaviors, which exists in video, audio, and text modalities. Although these modalities often show in time-series forms, current research offers limited exploration of the complex intra-modal temporal dynamics inherent to each modality, failing to extract the depression-related cues in a global view. While many methodologies attempt to exploit the multifaceted information encoded across modalities via decision-level or feature-level fusion techniques, they often fall short in effectively representing pairwise inter-modal relationships, which is the key to utilize the distinct complementary relationship between each modality pair. This paper presents a novel graph-based multimodal fusion approach, which can model intra-modal and inter-modal dynamics conveniently using a graph representation. It adopts undirected edges to link not only temporally continuous, pre-extracted features of each modality, but also temporally aligned features across each pair of modalities. This ensures the seamless propagation of global information across temporal dimensions and helps capture the pairwise inter-modal dynamics. We conduct experiments on the E-DAIC dataset to prove our approach's effectiveness, with an RMSE of 4.80 and a CCC value of 0.563, which rival the top-performing method. We also experiment on the AFAR-BSFP dataset to show the generality of our approach. Our code will be made publicly available.
Cricket: A Self-Powered Chirping Pixel
Creators: name: Nayar, Shree K.
name: Klotz, Jeremy
name: Nanda, Nikhil
name: Fridberg, Mikhail
Publisher: name: arXiv
Year: 2025
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: We present a sensor that can measure light and wirelessly communicate the measurement, without the need for an external power source or a battery. Our sensor, called cricket, harvests energy from incident light. It is asleep for most of the time and transmits a short and strong radio frequency chirp when its harvested energy reaches a specific level. The carrier frequency of each cricket is fixed and reveals its identity, and the duration between consecutive chirps is a measure of the incident light level. We have characterized the radiometric response function, signal-to-noise ratio and dynamic range of cricket. We have experimentally verified that cricket can be miniaturized at the expense of increasing the duration between chirps. We show that a cube with a cricket on each of its sides can be used to estimate the centroid of any complex illumination, which has value in applications such as solar tracking. We also demonstrate the use of crickets for creating untethered sensor arrays that can produce video and control lighting for energy conservation. Finally, we modified cricket's circuit to develop battery-free electronic sunglasses that can instantly adapt to environmental illumination.
description: 13 pages, 18 figures. Project page: https://cave.cs.columbia.edu/projects/categories/project?cid=Computational%20Imaging&pid=Cricket%20A%20Self-Powered%20Chirping%20Pixel
Supplementary document for Chirality-controlled second-order nonlinear frequency conversion in lithium niobate film metasurfaces - 7238223.pdf
Creators: name: Xu, Hangsheng
name: Ma, Ruize
name: Zhu, Ying
name: Dong, Anlong
name: Jiang, Haiyan
name: Gao, Weiqing
name: Qin, Meng
name: Liu, Jian Qiang
name: Wu, Feng
name: Li, Hong-Ju
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: This supplementary material is organized as follows. In Section 1, we present the relationship between the second harmonic power and the input peak pump intensity. In Section 2, we describe the multipole decomposition method.
Efficient Traffic Control Protocols for Vehicular Ad-Hoc Networks
Creators: name: Bani Younes, Maram Younis Saleh
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: ECODE
ICOD
Bal-Traf
Abs-Bal
ITLC
ATLs

description: Traffic efficiency applications over road networks have been investigated recently using VANETs. This area of research is primarily concerned with increasing the traffic fluency over road networks. In this thesis, we first propose an efficient and accurate protocol to detect congested road segments in a downtown area using VANETs. We refer to this protocol as the Efficient COngestion DEtection (ECODE) protocol. ECODE evaluates three different traffic characteristics of each road segment including traffic speed, traffic density, and the time required to travel the segment. Moreover, ECODE evaluates traffic characteristics and detects the congestion level in each direction of the road segment. In addition, we propose an intelligent, dynamic, distributed, and real-time path recommendations protocol. We refer to this protocol as Intelligent path reCOmenDation (ICOD) protocol. ICOD is the first path recommendation protocol that does not rely on a central database of gathered traffic data for each area of interest. Eliminating centralized behavior resolves bottleneck as well as single point of failure problems, which in turn minimizes congestion and collision problems in VANETs. Furthermore, ICOD selects the path towards each destination in a hop-by-hop manner, which makes the turn decision at each road intersection more accurate and real-time. Different variants of ICOD are introduced that consider travel time, travel distance, fuel consumption, gas emissions, and context-awareness of each road segment parameters. Moreover, two traffic balancing mechanisms are proposed in this thesis to distribute traffic over the road network evenly, namely Bal-Traf and Abs-Bal. These mechanisms eliminate the highly congested road segment scenarios that are caused by the path recommendation protocol. Bal-Traf detects and eliminates the highly congested output road segment at each road intersection. However, Abs-Bal aims to keep the traffic density balanced among all output road segments at each road intersection. Finally, we propose an Intelligent Traffic Light Controlling (ITLC) algorithm to schedule the phases of each traffic light at isolated road intersections. This algorithm aims to decrease the queuing delay time of competing traffic flows and to increase the throughput of each signalized road intersection. ITLC has also been adapted in this thesis to the Arterial Traffic Lights (ATLs) algorithm for arterial road network scenarios. In ATLs the expected platoons on the arterial street are considered in the scheduling algorithm of each traffic light located on the arterial street coordinates. Transmitting packets among these traffic lights report the main characteristics of each predicted platoon.
Examining Coach Pathways and Learning Situations: High-Performance Head Hockey Coaches who Played Goal
Creators: name: Crickard, Travis
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Coach pathways
High-Performance
Coach learning

description: Using archival analysis and interviews this study examined the career pathways, learning experiences, and athletic experiences of 11 high-performance head hockey coaches who played goal in ice hockey. Guided by the learning situations discussed in Wright, Trudel, and Culver (2007) the interviews revealed four important learning experiences common to all the coaches: coach interactions, books and videotapes, coach clinics and academic education, and experiences related to playing and coaching. Like Werthner and Trudel (2009) the results indicated that certain similarities aside, each coach’s career pathway is idiosyncratic with elite athletic experience being an important, but not imperative, aspect of high-performance coaches’ career development. The findings provide insight into how these individuals acquired their coaching knowledge and provide a more complete picture of the developmental pathways associated with becoming a high-performance head hockey coach.
Negotiating positive student identities: what can we learn by listening to the voice of parents?
Creators: name: Hore, Roslyn
name: Ballantyne, Glenda
Publisher: name: Swinburne
Year: 2024

description: The question as to why some children fail to thrive in our education systems in the Western world has motivated a large and diverse body of research that spans many decades and the ongoing debate shows, that the question of success or failure is a complex one. One element of that complex picture, not yet fully understood, is the intergenerational character of educational failure and the social processes through which this transmission occurs. This paper reports on an ongoing qualitative study concerned with the intergenerational factor which has revealed that the beliefs parents bring to their interactions with their child regarding educational matters can have an immense impact, in complex ways, on their child's reality as a learner and in terms of their child's motivation to succeed in the education system. These beliefs arise in part from a parents own experiences in the education system and it seems that they can be passed down through the generations. It is emerging in this research that 'class' is a factor influencing the beliefs parents bring to important interactions regarding their child's reality in the education system.
title: Role of culture, context, and parenting in the development of child emotion regulation
Creators: name: Bozicevic, Laura
Publisher: name: University of Reading
Year: 2022

description: The ability to regulate one’s emotions, which is progressively acquired from birth, is 
key to healthy socio-emotional and psychological functioning. Research suggests that 
predictors of child emotional development, including parenting, child temperament, context 
and culture, contribute to the socialisation of emotion regulation (ER) and exert their 
influence both directly, and in interaction with one another. However, little empirical 
research has considered these factors together.
This PhD thesis includes three longitudinal studies conducted in the UK, Italy, and 
South Africa, and focuses on the influence of mother-infant interactions assessed in the first 
three months (in particular, maternal sensitivity and specific contingent responses to infant 
socio-emotional communication) on later child ER (from 9 months to 2 years). Across 
studies, both reactive (i.e., latency and intensity of distress) and regulatory components 
(i.e., regulative behavioural strategies) of ER were assessed as outcomes, with differences in 
design and approach, according to study aims and child age. Two studies were cross-cultural, comparing the UK with either samples from South Africa (Stellenbosch and 
Khayelitsha – paper 1), or from Italy (paper 2), while the last study was conducted in the UK, 
on a sample different from the ones used in the previous studies (paper 3).
The main findings from the three papers are: a) no differences in global levels of 
sensitive responsiveness were found across cultures, but variations in the expression of 
responsiveness emerged (papers 1 and 2); b) differences in the reactive component of ER 
did not emerge across cultures, whereas differences in the type of ER strategies employed 
to face frustration did emerge (papers 1 and 2); c) early maternal responsiveness mediated 
the association between culture and later child ER (papers 1 and 2); d) in the UK sample, 
maternal sensitivity mediated the association between type of context and ER (paper 3);
and e) the association between maternal sensitivity and child ER varies according to 
temperament (paper 3).
Supplementary document for Ptychographic Mueller matrix imaging (PMMI): principle and proof-of-concept demonstration - 7254742.pdf
Creators: name: Gong, Ming
name: Lliu, Li
name: Du, Jinxiang
name: Zhuang, Bailin
name: Liu, Jiamin
name: Gu, Honggang
name: Liu, Shiyuan
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: supplemental information
Practical guide for evaluation and management of beta-lactam allergy: position statement from the Canadian Society of Allergy and Clinical Immunology
Creators: name: Jeimy, Samira
name: Ben-Shoshan, Moshe
name: Abrams, Elissa M.
name: Ellis, Anne K.
name: Connors, Lori
name: Wong, Tiffany
Publisher: name: BioMed Central
Year: 2020

description: The vast majority of individuals labelled as allergic are not deemed truly allergic upon appropriate assessment by an allergist. A label of beta-lactam allergy carries important risks for individual and public health. This article provides an overview of beta-lactam allergy, implications of erroneous beta-lactam allergy labels and the impact that can be provided by structured allergy assessment. We provide recommendations on how to stratify risk of beta-lactam allergy, beta lactam challenge protocols as well as management of patients at high risk of beta-lactam allergy.
Large-Scale Production in 'Escherichia coli' TG1 and Purification of Llama Single Domain Antibody ToxA5.1 Against 'Clostridium difficile' Toxin A
Creators: name: Parisien, Albert
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Single domain antibody
C. difficile toxin A
E. coli
Fermentation
pH-stat
Protein expression
Nickel nanoparticles
Protein purification
Hexahistidine-tagged recombinant protein

description: Drug resistant strains of Clostridium difficile are a major health concern with over 3 million cases costing over 1 billion $ per year in the United-States. The diseases associated with these bacteria (CDAD) are toxin-mediated which offers a mean of treating and lessening the severity of CDAD symptoms. Toxin inactivation via antibodies therapy can drastically reduce CDAD morbidity and this project was aiming at investigating the large-scale production and recovery of a novel llama single domain antibody (pSJF2H-ToxA5.1) in recombinant Escherichia coli TG1 targeting C. difficile enterotoxin A (TcdA). In order to achieve these objectives, the project was divided into four segments: 1) ToxA5.1 being an intracellular recombinant protein, obtaining a high biomass production was the first step towards large-scale production. To achieve HCDC, effects of initial glucose concentration and pH-stat feeding strategy were studied; 2) Upon achieving HCDC, effects of parameters such as temperature, induction timing and media supplementation with complex nitrogen sources were investigated; 3) Once large-scale production of ToxA5.1 was obtained, the recombinant protein needed to be recovered and a selective cell lysis scheme where synergistic lysis effects of Triton X-100 and temperature were studied. And finally 4) Single-step purification using nickel nanoparticles (NNP) synthesized via a modified polyol method was studied. Combining the HCDC strategy with a temperature shift and yeast extract addition at the time of induction, ToxA5.1 concentration of 127 mg/L was obtained. Synergistic and selective cell lysis using Triton X-100 and temperature was achieved where 95% of the available ToxA5.1 was recovered and still functional while ToxA5.1 fraction in the resulting lysate increased to 27% in the cell lysate. Single-step purification was achieved using the synthesized NNP which proved to be highly selective and could be used up to five times. Diameter of the NNP synthesized was controlled by using various concentration of ranging from 131 ± 80 nm to 47 ± 20 nm. Using experimental data from binding isotherm, the ToxA5.1-NNP system was modeled.
Synthesis of A-CD Estrogens with Potential for Hormone Replacement Therapy. Isolation of Sesquiterpene Lactones from Neurolaena lobata and Diterpenoids from Leretia cordata
Creators: name: Choueiri, Christine
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013

description: The use of estrogen supplements by postmenopausal women has been associated with increased risks of uterine and breast cancer. There are two possible mechanisms of toxicity: estradiol can promote breast cancer cell proliferation through estrogen receptor-α (ERα) and get metabolized to genotoxic ortho-quinones. The first part of this thesis describes the synthesis of a new series of non-carcinogenic A-CD estrogen agonists for hormone replacement therapy (HRT) with either the cis (1) or the trans (2) CD-ring junction. These compounds closely resemble estradiol (3) but lack the B-ring, allowing the ligands to adopt different conformation inside the binding pocket. One example of BC-spirolactone estrogen (4) is also described. Binding affinity and selectivity to both estrogen receptor subtypes ERα and ERβ were determined primarily by their Relative Binding Affinities (RBAs) and their Relative Transcription Activities (RTAs). Some ligands had binding affinities in the same order of magnitude as for estradiol itself and two were less toxic than estradiol. This work also shows that the receptors can accept almost equally well isomers that have very different molecular shapes. The second part of the thesis describes an ethno-pharmacological project on Neurolaena lobata (Asteraceae), a medicinal plant used in folk medicine in Central America to treat various symptoms such as headaches, fevers and skin diseases. Isolation and identification of five sesquiterpene lactones (5) are described and bioassays results for inflammation are presented. All compounds isolated from the leaves of N. lobata were potent inhibitor of the pro-inflammatory cytokine TNFα, some even more than the positive control Parthenolide. The final section of this work presents the first phytochemical study of the plant Leretia cordata (Icacinaceae). Characteristic secondary metabolites and the potential biological activities of the isolated compounds were identified. Four known complex polyoxygenated diterpenoids (6) with known anti-cancer properties have been isolated.
Supplementary document for Compensating Loss via Non-Hermiticity in Optically Trapped and Bounded Particles - 7248019.pdf
Creators: name: Li, Yang
name: Li, Xiao
name: Ng, Jack
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: Compensating Loss via Non-Hermiticity in Optically Trapped and Bounded Particles_ Supplement 1
Particle Based 3D Hair Reconstruction Using Kinect and High Resolution Camera
Creators: name: Li, Zhongrui
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015

description: Hair modeling based on real-life capturing is a rising and challenging topic in the field of human modeling and animation. Typical automatic hair capture methods use several 2D images to reconstruct 3D hair model. Most of them usually adopt 3D polygons to present hair strands, and a few recent strand-based methods require heavy hardware settings. We introduce an approach to capture real hair using affordable and common devices such as a depth sensor and a camera to reconstruct a 3D hair model based on particle system. KinectTM sensor from Microsoft is chosen to capture 3D depth data. However, as Kinect 3D depth data are known to be noisy and 2D texture image to be of low quality, an additional DSLR camera is employed in the system in order to capture high resolution image for hair strand extraction. The proposed approach registers the 3D hair point cloud and high resolution image in the same space, extracts the hair strands manually from the image, and then generates 3D hair strands based on Kinect depth information. Eventually, a particle based 3D hair model is reconstructed. The proposed method captures 360-degree views by collecting datasets of real-life hair with four sets of Kinect sensors and DSLR cameras in four viewpoints. We register the DSLR camera image in the space of Kinect to build the mapping relationship between 2D and 3D. Therefore, the image from the DSLR camera can be mapped on the point cloud replacing the existing Kinect texture image, resulting in a new high-quality texture image of the 3D data. Next we manually select the hair strands in the high resolution image and we use control points to represent hair strand as a spline curve. These 2D control points are then projected on the 3D point cloud in order to obtain the corresponding 3D information. In 2D image, some hair strands are partially occluded by some other hair strands, the result is that the occluded hair strand is separated into two segments in 3D. An algorithm is applied to analyze and build the connection between the hair strand segments. Meanwhile some refinement works are done with the 3D hair strands, filtering and interpolation techniques are utilized on the 3D hair strand splines to generate smoother 3D hair strands. Finally we reconstruct the 3D hair model, where the strands are represented in the particle system. Our method, combining a depth sensor and an high resolution camera, is novel and has many advantages which other approaches do not have; (i) hardware setting is simple and affordable; (ii) combination of high-quality image of DSLR and depth of Kinect takes advantage of each of them; (iii) the 2D and 3D combined method allows us to repair and refine the 3D data; (iv) Spline-based hair representation can be used to construct a hair particle system which has many advantages of hair animation and simulation.
Acute and Chronic Energy Deprivation Improves Smell Performance and Heightens the Rewarding Value of Food: How Modality of Deprivation Differently Impacts Olfaction, Food Reward, Appetite, Peptide Hormones, and Energy Intake
Creators: name: Cameron, Jameason
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Food reward
Appetite
Food hedonics
Fasting
Diet
Exercise
Olfaction

description: The study of feeding behavior, and in particular the study of subjective hedonic experience and objective measures of motivation, are central to understanding how appetite regulation can be compromised in certain individuals. Furthermore, with an integrated picture of physiological and behavioral changes that can occur as a result of energy deprivation what emerges is a better understanding of how palatable food can disrupt attempts at regulating body weight at lower levels of body energy stores. In Article I, the genetic association study examining a potential role for a dopamine-related polymorphism in weight loss, it was shown that contrary to the main hypothesis there was no association between TaqIA polymorphism and the amount of body weight loss. In Article II, it was shown that palatability and olfaction ratings increased as a result of a 24 hour fast and females demonstrated larger improvements in overall olfactory performance. Initial body weight was positively related to improved odor detection threshold and total odour score (TDI). Using the same population sample as Article II, Article III highlights that higher sensitivity to reward and disinhibition scores correlated with responding for palatable snack food stimuli in the relative-reinforcing value of food (RRV) task, further indicating that RRV has strong ties with impulsivity. There was a demonstrable lack of negative alliesthesia under the fasted condition where, after a 75% increase in ad libitum energy intake (EI) relative to the fed condition, this greater amount of food consumed was still rated as being more palatable than the lesser amounts consumed under the fed condition. In Article IV it was shown that an equicaloric (-25%) energy deficit by diet alone was a greater challenge to appetite regulation and resulted in greater compensatory increases in EI than deprivation by exercise alone. Independent of deprivation modality there were significant improvements in odour threshold scores. TDI score increased only under diet alone; furthermore, the noted increase in mean TDI score was positively related to increased ad libitum EI. The picture that emerges is that, acutely, a complete fast has more pronounced effects on appetite and ad libitum EI than dieting alone, which in turn had greater effects than exercise alone or controls. Also, TDI improved under all three methods of energy deprivation, but moreso under conditions of deprivation by diet alone.
Untitled Item
Creators: name: Grande-De-Prado, Mario
Publisher: name: figshare
Year: 2020
Subjects: Education

description: Artículo (en realidad, dos), sobre las ciudades de León y Astorga durante la Guerra de Independencia, para su uso con el juego de rol histórico 1808 de Ediciones Sombra.Publicado en la revista Desde el Sótano, 81.
The Impact of Increased Number of Acute Care Beds to Reduce Emergency Room Wait Time
Creators: name: McKay, Jennifer
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: emergency room wait times
hospital length of stay
emergency department crowding
cost benefit analysis

description: Reducing ED wait times is a top health care priority for the Ontario government and hospitals in Ontario are incentivised to meet provincial ED wait time targets. In this study, we considered the costs and benefits associated with increasing the number of acute-care beds to reduce the time an admitted patient spends boarding in the ED. A shorter hospital LOS has often been cited as a potential benefit associated with shorter ED wait times. We derived a multivariable Cox regression model to examine this association. We found no significant association between ED boarding times and the time to discharge. Using a Markov model, we estimated an increased annual operating cost of $2.1m to meet the prescribed wait time targets. We concluded that increasing acute-care beds to reduce ED wait times would require significant funding from hospitals and would have no effect on total length of stay of hospitalized patients.
Phantom Domain Finite Element Method: A novel approach for heterogeneous materials
Creators: name: He, Tianlong
name: Karamian-Surville, Philippe
name: Choï, Daniel
Publisher: name: arXiv
Year: 2025
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: In this paper, we introduce the Phantom Domain Finite Element Method (PDFEM), a novel computational approach tailored for the efficient analysis of heterogeneous and composite materials. Inspired by fictitious domain methods, this method employs a structured mesh to discretize the entire material domain while utilizing separate, independent meshes for the inclusions. These inclusion meshes are coupled to the structured mesh via a substitution matrix, enabling them to act as phantom meshes that do not directly contribute to the final system of equations. This framework offers significant advantages, including enhanced flexibility in handling complex inclusion geometries and improved computational efficiency. To assess the accuracy and robustness of the proposed method, numerical experiments are conducted on structures containing inclusions of various geometries. In order to emphasize the efficiency of the PDFEM method, a numerical simulation is presented to highlight its advantages in the case of long natural fibers, such as flax and linen. These simulations are compared against FEM calculations, demonstrating the efficiency of PDFEM. Indeed, meshing such fine structures requires an extremely high number of elements, and in some cases, meshing becomes particularly challenging due to the complexity of the geometries.
Contributions to the Design of RF Power Amplifiers
Creators: name: Acimovic, Igor
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Power amplifier (PA)
Doherty amplifier
load-pull measurement
efficiency enhancement
peak-to-average
impedance matching
linearity
impedance modulation

description: In this thesis we introduce a two-way Doherty amplifier architecture with multiple feedbacks for digital predistortion based on impedance-inverting directional coupler (transcoupler). The tunable two-way Doherty amplifier with a tuned circulator-based impedance inverter is presented. Compact N-way Doherty architectures that subsume impedance inverter and offset line functionality into output matching networks are derived. Comprehensive N-way Doherty amplifier design and analysis techniques based on load-pull characterization of active devices and impedance modulation effects are developed. These techniques were then applied to the design of a two-way Doherty amplifier and a three-way Doherty amplifier which were manufactured and their performance measured and compared to the amplifier performance specifications and simulated results.