cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
INFECÇÃO POR RETROVIROSES EM FELINOS DOMÉSTICOS (FELIS SILVESTRIS CATUS) NA REGIÃO NORTE DO ESTADO DO TOCANTINS
Creators: name: Sebastiana Adriana Pereira SOUSA
name: Helcileia Dias SANTOS
name: Taiã Mairon Peixoto RIBEIRO
name: Samara Rocha GALVÃO
name: Ronaira Assunção SILVA
name: Ruth Martins SANTOS
name: Maria Cirlene Gomes de Oliveira - SOBRAL
name: Cristina da Silva ASSIS
name: Valéria de Sá JAYME
Publisher: name: Zenodo
Year: 2024
Subjects: Gato
Retrovírus
Epidemiologia
Fator de risco

description: RESUMO

 

Os vírus da imunodeficiência felina (FIV) e vírus da leucemia felina (FeLV) são retroviroses de distribuição mundial. Os felinos acometidos são predispostos a infecção por agentes infecciosos secundários e ao desenvolvimento de síndromes graves devido à imunossupressão causada pelos vírus. Diante da escassez de estudos na região Norte do Brasil e da importância do conhecimento da distribuição e frequência destas viroses para a adoção de medidas preventivas, objetivou-se investigar a ocorrência de anticorpos para FIV e FeLV em felinos domésticos do município de Araguaína, Estado do Tocantins, e identificar características populacionais relacionadas às infecções. Soro de 84 animais, 47 fêmeas e 37 machos, foi submetido a um ensaio imunocromatográfico. A frequência observada para FIV e FeLV foi de 2,38% (2/84; IC: 2,29% - 8,34%) e 11,9% (10/84; IC: 5,86% - 20,81%)

respectivamente. Apenas um animal (1,2%; IC: 0,06% - 5,80%) apresentou coinfecção por ambos os agentes infecciosos. Dentre os felinos reagentes para FeLV, 70% (7/10) foram machos, 100% (10) adultos e 80% (8/10) assintomáticos. Variáveis como sexo, faixa etária, raça e condição clínica não apresentaram associação com as infecções (p > 0,05). Os resultados deste estudo demonstram que infecções por FIV e FeLV estão presentes em felinos domésticos de Araguaína-TO e destaca a necessidade de diagnóstico precoce e proteção dos animais, considerando o potencial imunossupressor e a facilidade de transmissão e dispersão dessas retroviroses, bem como os cuidados necessários ao bem-estar dos animais infectados.
title: The Thousand Cataluñas of Europe
Creators: name: Cannizzaro, Enzo
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: Cataluñas
subject: independence
subject: Spanish Constitutional law
subject: secession in International law
subject: European Union
subject: pluralistic representation of States

description: European Papers - A Journal on Law and Integration, 2017 2(2), 463-466
description: Irrespective of the perspective from which one looks at the Catalonian events, which are still unfolding under our incredulous eyes, the impression can only be univocal: Spain is right and Catalonia is wrong. The claim of the Spanish Government to preserve the unity of the nation is well founded; conversely, the independence proclaimed by the Catalonian Government amounts to an extra ordinem revolutionary act. This is the conclusion that must be naturally drawn from an inquiry conducted on the basis of Spanish Constitutional law. This would inevitably also be the conclusion to be drawn from an international law perspective. The question thus arises as to whether in European law this monolithic representation of statehood can be attenuated in favour of institutional solutions that reflect more faithfully the pluralistic nature of the modern forms of State. The adoption of a pluralistic representation of States within the EU, and in particular, a transformation of the composition of the Council into a permanent body, including not only representatives of the Governments of the Member States, but also of their National Parliaments and, where present, also of their sub-national communities, may considerably defuse the tendency to independentism that is still present around Europe.
Additional file 1 of Factors impacting clinical data and documentation quality in Australian aged care and disability services: a user-centred perspective
Creators: name: Tshering, Gap
name: Troeung, Lakkhina
name: Walton, Rebecca
name: Martini, Angelita
Publisher: name: figshare
Year: 2024
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences

description: Supplementary Material 1
title: Introduction: The New Frontiers of EU Administrative Law and the Scope of Our Inquiry
Creators: name: Cremona, Marise
name: Leino, Päivi
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: European Union
subject: administrative law
subject: external relations
subject: accountability
subject: discretion
subject: EU institutions

description: European Papers - A Journal on Law and Integration, 2017 2(2), 467-488
description: I. The EU as a global administrative actor. - II. Development of EU administrative law and external relations: setting the scene. - III. Administrative action as instrumental action in external relations. - IV. Accountability: actors, fora and different types of act. - V. Mapping administrative action in EU external relations. - VI. Discretion.
description: This Article introduces our study into the operation of administrative law in EU external relations by introducing its general themes and fields of study. It starts by characterising the EU as a global actor and by illustrating how EU administrative law has developed in general, and in the area of external relations in particular. It then moves to examine the instrumental role that administrative law plays in advancing the EU's external policy objectives, and the difficulties involved, following from the general way in which many of these objectives have been defined. Building on Bovens' definition of accountability, we lay down a main framework for studying accountability in this context, and its different dimensions studied in the individual Articles: legal, political, financial, administrative and social. This Article then provides a general comparison of administrative action in the area of external action, building on general typologies of EU administrative action, with a view to laying the ground for an examination of the extent to which external relations is special. Finally, it closes with a brief introduction to one of the key themes in this Special Section: the scope of institutional discretion, and its link to the overall accountability of EU action in this area.
title: The External Administrative Layer of EU Law-making: International Decisions in EU Law and the Case of CETA
Creators: name: Mendes, Joana
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: global regulatory regimes
subject: international decisions
subject: public authority
subject: non-binding acts
subject: procedures
subject: CETA

description: European Papers - A Journal on Law and Integration, 2017 2(2), 489-517
description: I. The international regulation of public goods: legal challenges. - II. International decisions by CETA bodies. - III. Decisions of international bodies: a source of EU law. - IV. The external administrative layer of EU law. - IV.1. Interpretative effects: validating EU law. - IV.2. Authoritative international decisions. - IV.3. A next step for interpretative effects? - IV.4. Validating, but not invalidating EU law. - V. Strong in substance, weak in procedure. - VI. The EU Treaty procedure. - VII. The CETA bodies making EU law.
description: The legal status of binding and non-binding international decisions adopted by global regulatory bodies in EU law, their authority (as acknowledged in the case law of the CJEU) and legal effects allow one to characterise them as the external administrative layer of EU law-making. Mega-regional agreements, of which the Comprehensive Economic and Trade Agreement (CETA) is an instance, have the potential to expand this tier of law. This Article maps the substantive legal effects of international decisions in EU law as expounded by the CJEU, arguing that the case law the Court developed is transposable to future decisions of CETA bodies. Furthermore, it contrasts their possible substantive impact in EU law with the weaknesses of procedural controls over the exercise of public authority by those bodies.
title: The Extraterritorial Reach of EU Environmental Law and Access to Justice by Third Country Actors
Creators: name: Hadjiyianni, Ioanna
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: environment
subject: climate change
subject: extraterritorial implications
subject: access to justice
subject: Aarhus Convention
subject: third country

description: European Papers - A Journal on Law and Integration, 2017 2(2), 519-542
description: I. Introduction. - II. The legal phenomenon of IEMEIs. - II.1. IEMEIs regulating conduct abroad on the basis of environmental regulatory requirements. - II.2. IEMEIs regulating trade: market access conditions and obligations on Third Country actors. - II.3. Compliance with IEMEIs: "contingent unilateralism", equivalence and flexibility. - III. Access to justice. - III.1. Avenues for access to justice for different kinds of third country actors. - III.2. Standing. - III.3. The Aarhus Convention and access to justice. - IV. Conclusion.
description: The EU conducts its external relations through different types of tools, including through unilateral domestic measures with extraterritorial implications that extend its regulatory power to processes occurring partly abroad. These are increasingly prevalent in the area of environmental protection, including climate change. Examples include the sustainability criteria for biofuels, the inclusion of aviation emissions in the EU emissions trading system, ship recycling, exports of electrical and electronic waste and imports of timber. Because these measures are unilateral in nature, developed within the EU legal order, but have important legal and policy effects beyond EU borders, they raise complex legitimacy questions and may give rise to an external accountability gap. The role of EU administrative law, which controls the exercise of EU public power, is important in "disciplining" the exercise of EU power beyond EU borders and filling this gap. The Article explores some of the novel regulatory techniques employed in these kinds of internal measures to conduct external action and how administrative law responds to their complexities. It focuses on access to justice in the EU legal order in exploring the extent of an external accountability gap. The constraints of accessing the EU judicial system may accentuate the external accountability gap if the EU cannot be held into account on the basis of its own rule of law by third country actors affected by its action.
AUTONOMOUS CARS AND DRIVERLESS LETHAL AUTONOMY
Creators: name: Nyagudi, Nyagudi Musandu
Publisher: name: figshare
Year: 2015
Subjects: subject: Probability
subject: Personality, Social and Criminal Psychology
subject: Information Systems
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Distributed Computing
subject: Applied Computer Science
subject: 80309 Software Engineering
subject: Artificial Intelligence and Image Processing
subject: Computer Engineering
subject: Anthropology
subject: FOS: Sociology

description: “The small picture” - make an advanced autonomous/driverless car. Lots of algorithms, sensors, computers and other gizmos. Now get it to take you to work, park itself and seamlessly run your family errands around the city. Taking grandma
to the doctor for the medical check-up, getting the children from school, etc. With Radar, Lidar and other sensors, the car steering with ease through the traffic, no driver to pay, that is another plus, fuel/energy efficiency, yet another plus. It is a bold
new world and the sky is the limit. Without the resolution of “small picture” issues there is no functioning autonomous/self-driving car, and without resolution of “THE BIG PICTURE” issues such as Driverless Lethal Autonomy there is no successful,
viable and/or safe autonomous car.
Harmonic analysis of little $q$-Legendre polynomials
Creators: name: Kahler, Stefan
Publisher: name: arXiv
Year: 2020
Subjects: subject: Functional Analysis (math.FA)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 33D45 (Primary) 42C10, 43A30, 43A62 (Secondary)

description: Many classes of orthogonal polynomials satisfy a specific linearization property giving rise to a polynomial hypergroup structure, which offers an elegant and fruitful link to Fourier analysis, harmonic analysis and functional analysis. From the opposite point of view, this allows regarding certain Banach algebras as $L^1$-algebras, associated with underlying orthogonal polynomials. The individual behavior strongly depends on these underlying polynomials. We study the little $q$-Legendre polynomials, which are orthogonal with respect to a discrete measure. We will show that their $L^1$-algebras have the property that every element can be approximated by linear combinations of idempotents. This particularly implies that these $L^1$-algebras are weakly amenable (i. e., every bounded derivation into the dual module is an inner derivation), which is known to be shared by any $L^1$-algebra of a locally compact group; in the polynomial hypergroup context, weak amenability is rarely satisfied and of particular interest because it corresponds to a certain property of the derivatives of the underlying polynomials and their (Fourier) expansions w.r.t. the polynomial basis. To our knowledge, the little $q$-Legendre polynomials yield the first example of a polynomial hypergroup whose $L^1$-algebra is weakly amenable and right character amenable but fails to be amenable. As a crucial tool, we establish certain uniform boundedness properties of the characters. Our strategy relies on the Fourier transformation on hypergroups, the Plancherel isomorphism, continued fractions, character estimations and asymptotic behavior.
description: The paper is essentially also a part of the first version of arXiv:1806.00339 [math.FA]. It is now a separate paper because the associated symmetric Pollaczek part of arXiv:1806.00339 [math.FA] was extended. Compared to the (first version of) arXiv:1806.00339, we extended and added some results on little $q$-Legendre polynomials, modified the notation and added some graphics/literature
title: External Participants v. Internal Interests: Principles of EU Administrative Law in Anti-dumping Investigations
Creators: name: Korkea-aho, Emilia
name: Sankari, Suvi
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: trade defence instruments
subject: anti-dumping procedure
subject: external interests
subject: EU administrative law
subject: rights of the defence
subject: equal treatment

description: European Papers - A Journal on Law and Integration, 2017 2(2), 543-570
description: I. Introduction. - II. Discretion or clear rules? The "fundamental importance" of the administrative law framework. - III. Interests involved in anti-dumping policy-making. - III.1. Decision to initiate investigations. - III.2. Decision on anti-dumping duties. - IV. Three functions of participation. - IV.1. Mechanism to collect expertise and information. - IV.2. Participation as constraining the exercise of administrative powers. - IV.3. Democratic anti-dumping regime: participation as contributing to accountability? - V. Concluding discussion: do administrative law principles protect equally?
description: Anti-dumping policy is key among the EU trade defence instruments. Although formally a political regime to restrict cheap imports to the EU, its daily operations target individual companies, predominantly from third countries. Finding a balance between multilateral trade rules and the individualised and international decision-making requires a well-functioning administrative procedure to protect the rights of the defence. Anti-dumping decision-making is exercised according to WTO-compliant rules laid down in the Basic Regulation (i.e. Regulation (EU) 2016/1036) which governs the Commission's exercise of discretion. The EU has put in place a procedurally elaborated and territorially blind administrative framework, which invites external participation and promotes reciprocity in third-country procedures for EU producers. The framework extends beyond the rights of the defence for those affected by the decisions, to a broader participation. Formally respecting the rights of participants, including their interests, and treating them equally regardless of geographical origin does not negate the fact that certain interests weigh more than others. The disparity is not created by inadequacies or limitations of administrative law, but rather by the overall framing of the process to cater to the needs of domestic EU industry and political tit-for-tat thinking. The lack of soft law rules further augments executive discretion in anti-dumping decision-making, and accountability for Commission choices is difficult to enforce. In addition to insisting on transparency and the rights of the defence, a complementary way to increase and improve accountability would be to acknowledge a more substantive duty to state reasons in anti-dumping policy-making.
Parker Solar Probe Observations of Energetic Particles in the Flank of a Coronal Mass Ejection Close to the Sun
Creators: name: Schwadron, N. A.
name: Bale, Stuart D.
name: Bonnell, J.
name: Case, A.
name: Shen, M.
name: Christian, E. R.
name: Cohen, C. M. S.
name: Davis, A. J.
name: Desai, M. I.
name: Goetz, K.
name: Giacalone, J.
name: Hill, M. E.
name: Kasper, J. C.
name: Korreck, K.
name: Larson, D.
name: Livi, R.
name: Lim, T.
name: Leske, R. A.
name: Malandraki, O.
name: Malaspina, D.
name: Matthaeus, W. H.
name: McComas, D. J.
name: McNutt, R. L.
name: Mewaldt, R. A.
name: Mitchell, D. G.
name: Niehof, J. T.
name: Pulupa, M.
name: Pecora, Francesco
name: Rankin, J. S.
name: Smith, C.
name: Stone, E. C.
name: Szalay, J. R.
name: Vourlidas, A.
name: Wiedenbeck, M. E.
name: Whittlesey, P.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: We present an event observed by Parker Solar Probe at $\sim$0.2 au on March 2, 2022 in which imaging and \emph{in situ} measurements coincide. During this event, PSP passed through structures on the flank of a streamer blowout CME including an isolated flux tube in front of the CME, a turbulent sheath, and the CME itself. Imaging observations and \emph{in situ} helicity and principal variance signatures consistently show the presence of flux ropes internal to the CME. In both the sheath, and the CME interval, the distributions are more isotropic, the spectra are softer, and the abundance ratios of Fe/O and He/H are lower than those in the isolated flux tube, and yet elevated relative to typical plasma and SEP abundances. These signatures in the sheath and the CME indicate that both flare populations and those from the plasma are accelerated to form the observed energetic particle enhancements. In contrast, the isolated flux tube shows large streaming, hard spectra and large Fe/O and He/H ratios, indicating flare sources. Energetic particle fluxes are most enhanced within the CME interval from suprathermal through energetic particle energies ($\sim$ keV to $>10$ MeV), indicating particle acceleration, and confinement local to the closed magnetic structure. The flux-rope morphology of the CME helps to enable local modulation and trapping of energetic particles, particularly along helicity channels and other plasma boundaries. Thus, the CME acts to build-up energetic particle populations, allowing them to be fed into subsequent higher energy particle acceleration throughout the inner heliosphere where a compression or shock forms on the CME front.
description: 41 pages, 19 figures, In Press
title: External Migration and Asylum Management: Accountability for Executive Action Outside EU-territory
Creators: name: Rijpma, Jorrit J.
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: EU migration and asylum policy
subject: external dimension
subject: executive action
subject: Charter of Fundamental Rights of the European Union
subject: accountability mechanisms
subject: cooperation with third countries

description: European Papers - A Journal on Law and Integration, 2017 2(2), 571-596
description: I. Introduction. - II. EU visa policy. - II.1. Judicial review of decisions. - II.2. Judicial review in case of representation. - II.3. Humanitarian visa. - II.4. The extra-territorial applicability of the Charter. - III. Refugee resettlement. - III.1. EU Resettlement initiatives. - III.2. Resettlement in the refugee crisis. - III.3. Proposal for an EU resettlement mechanism. - III.4. Applicability of the Charter of Fundamental Rights to EU resettlement. - IV. Frontex coordinated joint operations in third country territory. - IV.1. Frontex as an executive actor. - IV.2. Responsibility for fundamental rights violations. - IV.3. Fundamental rights accountability mechanisms. - IV.4. Frontex as an external executive actor. - IV.5. Accountability for fundamental rights violations on third country territory. - V. Conclusions.
description: EU migration and asylum law, an area of administrative law par excellence, has from the moment that the EU acquired competences in this field, had a very strong external dimension. By looking at three areas of EU migration and asylum policy: visa policy, refugee resettlement and border management through Frontex operational activity, it will be shown that, notwithstanding significant improvements, a restrictive interpretation of the scope of EU law and the multi-level structure of EU executive action continue to pose challenges in holding the EU and its Member States to account.
Compactness of harmonic maps of surfaces with regular nodes
Creators: name: Park, Woongbae
Publisher: name: arXiv
Year: 2020
Subjects: subject: Differential Geometry (math.DG)
subject: Algebraic Geometry (math.AG)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 58E20, 32G15 (Primary) 53C43, 14H15 (Secondary)

description: In this paper, we formulate and prove a general compactness theorem for harmonic maps using Deligne-Mumford moduli space and families of curves. The main theorem shows that given a sequence of harmonic maps over a sequence of complex curves, there is a family of curves and a subsequence such that both the domains and the maps converge off the set of "non-regular" nodes. This provides a sufficient condition for a neck having zero energy and zero length. As a corollary, the following known fact can be proved: If all domains are diffeomorphic to $S^2$, both energy identity and zero distance bubbling hold.
description: 22 pages
title: Acknowledging the Impact of Administrative Power in the EU External Action
Creators: name: Vianello, Ilaria
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: administrative power
subject: public authority
subject: preparatory acts
subject: rule-making acts
subject: stabilisation and association process
subject: European Neighbourhood Policy

description: European Papers - A Journal on Law and Integration, 2017 2(2), 597-616
description: I. Introduction. - II. The impact of administrative power on the exercise of EU public authority. - II.1. Preparatory acts informing final decisions. - II.2. Rule-making acts: looking beyond technicalities. - III. The impact of administrative power on the exercise of third countries public authority. - III.1. Preparatory acts: take it or leave it. - III.2. Rule-making acts: "accept terms and conditions". - IV. Conclusion.
description: This Article identifies and explains the different impacts that the administrative activities implementing the Stabilisation Association Process (SAP) and the European Neighbourhood Policy (ENP) exercise on public power (of the Union and of third countries). Identifying the impact of the administrative power is an important passage in the study of administrative law in external relations, particularly in order to guarantee protection for affected parties. In carrying out such analysis, the Article will also classify the de facto administrative processes that are concealed in the modes of foreign governance constructed by the SAP and the ENP. The impact of the administrative activities implementing the two policies is neither incidental nor unforeseeable. Instead, it is often the outcome of processes that have crystalised over time.
ECQ$^{\text{x}}$: Explainability-Driven Quantization for Low-Bit and Sparse DNNs
Creators: name: Becking, Daniel
name: Dreyer, Maximilian
name: Samek, Wojciech
name: Müller, Karsten
name: Lapuschkin, Sebastian
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: The remarkable success of deep neural networks (DNNs) in various applications is accompanied by a significant increase in network parameters and arithmetic operations. Such increases in memory and computational demands make deep learning prohibitive for resource-constrained hardware platforms such as mobile devices. Recent efforts aim to reduce these overheads, while preserving model performance as much as possible, and include parameter reduction techniques, parameter quantization, and lossless compression techniques.
 In this chapter, we develop and describe a novel quantization paradigm for DNNs: Our method leverages concepts of explainable AI (XAI) and concepts of information theory: Instead of assigning weight values based on their distances to the quantization clusters, the assignment function additionally considers weight relevances obtained from Layer-wise Relevance Propagation (LRP) and the information content of the clusters (entropy optimization). The ultimate goal is to preserve the most relevant weights in quantization clusters of highest information content.
 Experimental results show that this novel Entropy-Constrained and XAI-adjusted Quantization (ECQ$^{\text{x}}$) method generates ultra low-precision (2-5 bit) and simultaneously sparse neural networks while maintaining or even improving model performance. Due to reduced parameter precision and high number of zero-elements, the rendered networks are highly compressible in terms of file size, up to $103\times$ compared to the full-precision unquantized DNN model. Our approach was evaluated on different types of models and datasets (including Google Speech Commands, CIFAR-10 and Pascal VOC) and compared with previous work.
description: 22 pages, 10 figures, 1 table
title: Administering EU Development Policy: Between Global Commitments and Vague Accountability Structures
Creators: name: Leino, Päivi
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: European Union
subject: development policy
subject: accountability
subject: financial audit
subject: participation
subject: developing countries

description: European Papers - A Journal on Law and Integration, 2017 2(2), 617-648
description: I. Introduction. - II. Legal framework. - II.1. The hard law: the Cotonou Convention and EU Regulations: multilateral or unilateral? - II.2. Post legislative guidance and the real world of implementing EU assistance. - II.3. The European Investment Bank: what role for voluntary policies? - III. Court and EO practice: setting the limits of procedural discretion. - IV. Audit and development co-operation: a means to ensure political accountability. - V. Thinking outside the box: towards a broader accountability concept.
description: The EU Treaties give voice to the strong global role that the EU asserts and illustrate how there would not seem to be many problems of a global scale that the EU would not like to contribute to solving. Managing development policy involves the translation of these extremely broad political objectives into individual projects that receive EU funding. In this process, fundamental political questions are frequently touched upon, and policy mistakes do take place. This Article discusses how the administrative procedures used to manage development policy contribute to establishing accountability. In EU documents, reference is frequently made to "ownership" by third countries involved. However, even though some elements of the packages build on negotiations with partners, in practice all key decisions relating to the allocation of money are unilateral EU decisions. "Ownership" in this context refers primarily to a wish that third country actors would embrace the EU agenda as its own and engage actively in its execution. The key challenges emerging from this discussion would seem to relate to unclear accountability relationships, in particular as regards the extraterritorial audience: the beneficiaries of EU assistance. In short, if you repeatedly declare that you plan to save the world, it just may happen that the world will wish to hold you accountable for that commitment.
title: Procedural Rights in the Context of Restrictive Measures: Does the Adversarial Principle Survive the Necessities of Secrecy?
Creators: name: Leppävirta, Liisa
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: restrictive measures
subject: procedural rights
subject: access to the file
subject: adversarial principle
subject: closed material procedure
subject: special advocates

description: European Papers - A Journal on Law and Integration, 2017 2(2), 649-669
description: I. Introduction. - II. The legal framework concerning restrictive measures. - III. The development of the right of access to the file. - IV. Access to "secret evidence" by the CJEU. - V. Conclusions.
description: Safeguarding fundamental procedural rights in the context of security concerns has been topical in the EU ever since the increased threats of terrorism post-9/11. This Article revisits the landmark case law on Kadi, which provided the premise for balancing due process rights and security concerns in the context of restrictive measures. The focus of this Article is on the specific procedural right of access to the file. The Article begins with a description of the legal framework on restrictive measures to the extent it is necessary for understanding the production and flow of information in the sanctions context. It then proceeds to scrutinise the development of the right of access to the file in this context through the Kadi cases and subsequent case law. The Article moves on to deal with the new developments in the Rules of Procedure of the General Court, which introduced a new closed procedure in cases concerning security related information or evidence, something that has clear implications for the targeted person's right of access to the file. The amendments to the Rules of Procedure challenge the traditional role of the Court and, so it is argued, pose some challenges to its legitimacy.
On the success probability of quantum order finding
Creators: name: Ekerå, Martin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Computational Complexity (cs.CC)
subject: Cryptography and Security (cs.CR)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We prove a lower bound on the probability of Shor's order-finding algorithm successfully recovering the order $r$ in a single run. The bound implies that by performing two limited searches in the classical post-processing part of the algorithm, a high success probability can be guaranteed, for any $r$, without re-running the quantum part or increasing the exponent length compared to Shor. Asymptotically, in the limit as $r$ tends to infinity, the probability of successfully recovering $r$ in a single run tends to one. Already for moderate $r$, a high success probability exceeding e.g. $1 - 10^{-4}$ can be guaranteed. As corollaries, we prove analogous results for the probability of completely factoring any integer $N$ in a single run of the order-finding algorithm.
description: This revision resolves a minor issue in Alg. 4, and addresses a number of other minor issues. It furthermore adds a number of extensions and clarifications, in particular with respect to potential optimizations. No key results or findings in the original version of the manuscript are affected by this revision
title: Is There an Accountability Gap in EU External Relations? Some Initial Conclusions
Creators: name: Cremona, Marise
name: Leino, Päivi
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2017
Subjects: subject: European Union
subject: administrative law
subject: external relations
subject: accountability
subject: discretion
subject: EU institutions

description: European Papers - A Journal on Law and Integration, 2017 2(2), 699-708
description: This short Article draws together some conclusions based on the contributions to the Special Section "The New Frontiers of EU Administrative Law: Is there a Gap in EU External Relations?". It concludes first that external action is a rich field in the application of EU administrative law. External policies are implemented and given effect through legal instruments and legally-prescribed procedures (including financial procedures) developed and controlled by administrative law and the Court of Justice. Second, as a result of mapping the types of administrative action in external policy fields we conclude that while the pattern of administrative action is shared with EU action more generally some distinctive types of external executive action can be identified, and external action demonstrates some distinctive qualities resulting in part from the multiplicity of actors and fora (including external) involved. Third, we conclude that despite very broad discretion in the implementation of policies the EU institutions are subject to administrative and legal constraints, including through the development of procedures in legislation, non-binding instruments and administrative practice. The Court has proved willing both to enforce procedural rules laid down in legislation and to require compliance with procedural principles such as the duty of care.
Formulation, optimization and characterization of cationic polymeric nanoparticles of mast cell stabilizing agent using the Box–Behnken experimental design
Creators: name: Balaram Gajra
name: Patel, Ravi R.
name: Chintan Dalwadi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Objective: The present research work was intended to develop and optimize sustained release of biodegradable chitosan nanoparticles (CSNPs) as delivery vehicle for sodium cromoglicate (SCG) using the circumscribed Box–Behnken experimental design (BBD) and evaluate its potential for oral permeability enhancement. Methods: The 3-factor, 3-level BBD was employed to investigate the combined influence of formulation variables on particle size and entrapment efficiency (%EE) of SCG-CSNPs prepared by ionic gelation method. The generated polynomial equation was validated and desirability function was utilized for optimization. Optimized SCG-CSNPs were evaluated for physicochemical, morphological, in-vitro characterizations and permeability enhancement potential by ex-vivo and uptake study using CLSM. Results: SCG-CSNPs exhibited particle size of 200.4 ± 4.06 nm and %EE of 62.68 ± 2.4% with unimodal size distribution having cationic, spherical, smooth surface. Physicochemical and in-vitro characterization revealed existence of SCG in amorphous form inside CSNPs without interaction and showed sustained release profile. Ex-vivo and uptake study showed the permeability enhancement potential of CSNPs. Conclusions: The developed SCG-CSNPs can be considered as promising delivery strategy with respect to improved permeability and sustained drug release, proving importance of CSNPs as potential oral delivery system for treatment of allergic rhinitis. Hence, further studies should be performed for establishing the pharmacokinetic potential of the CSNPs.
On the Trade-off between Redundancy and Local Coherence in Summarization
Creators: name: Cardenas, Ronald
name: Galle, Matthias
name: Cohen, Shay B.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Extractive summaries are usually presented as lists of sentences with no expected cohesion between them and with plenty of redundant information if not accounted for. In this paper, we investigate the trade-offs incurred when aiming to control for inter-sentential cohesion and redundancy in extracted summaries, and their impact on their informativeness. As case study, we focus on the summarization of long, highly redundant documents and consider two optimization scenarios, reward-guided and with no supervision. In the reward-guided scenario, we compare systems that control for redundancy and cohesion during sentence scoring. In the unsupervised scenario, we introduce two systems that aim to control all three properties -- informativeness, redundancy, and cohesion -- in a principled way. Both systems implement a psycholinguistic theory that simulates how humans keep track of relevant content units and how cohesion and non-redundancy constraints are applied in short-term memory during reading. Extensive automatic and human evaluations reveal that systems optimizing for -- among other properties -- cohesion are capable of better organizing content in summaries compared to systems that optimize only for redundancy, while maintaining comparable informativeness. We find that the proposed unsupervised systems manage to extract highly cohesive summaries across varying levels of document redundancy, although sacrificing informativeness in the process. Finally, we lay evidence as to how simulated cognitive processes impact the trade-off between the analyzed summary properties.
description: Accepted to JAIR
Formulation, optimization and characterization of cationic polymeric nanoparticles of mast cell stabilizing agent using the Box–Behnken experimental design
Creators: name: Balaram Gajra
name: Patel, Ravi R.
name: Chintan Dalwadi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Objective: The present research work was intended to develop and optimize sustained release of biodegradable chitosan nanoparticles (CSNPs) as delivery vehicle for sodium cromoglicate (SCG) using the circumscribed Box–Behnken experimental design (BBD) and evaluate its potential for oral permeability enhancement. Methods: The 3-factor, 3-level BBD was employed to investigate the combined influence of formulation variables on particle size and entrapment efficiency (%EE) of SCG-CSNPs prepared by ionic gelation method. The generated polynomial equation was validated and desirability function was utilized for optimization. Optimized SCG-CSNPs were evaluated for physicochemical, morphological, in-vitro characterizations and permeability enhancement potential by ex-vivo and uptake study using CLSM. Results: SCG-CSNPs exhibited particle size of 200.4 ± 4.06 nm and %EE of 62.68 ± 2.4% with unimodal size distribution having cationic, spherical, smooth surface. Physicochemical and in-vitro characterization revealed existence of SCG in amorphous form inside CSNPs without interaction and showed sustained release profile. Ex-vivo and uptake study showed the permeability enhancement potential of CSNPs. Conclusions: The developed SCG-CSNPs can be considered as promising delivery strategy with respect to improved permeability and sustained drug release, proving importance of CSNPs as potential oral delivery system for treatment of allergic rhinitis. Hence, further studies should be performed for establishing the pharmacokinetic potential of the CSNPs.
A CMDP-within-online framework for Meta-Safe Reinforcement Learning
Creators: name: Khattar, Vanshaj
name: Ding, Yuhao
name: Sel, Bilgehan
name: Lavaei, Javad
name: Jin, Ming
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Meta-reinforcement learning has widely been used as a learning-to-learn framework to solve unseen tasks with limited experience. However, the aspect of constraint violations has not been adequately addressed in the existing works, making their application restricted in real-world settings. In this paper, we study the problem of meta-safe reinforcement learning (Meta-SRL) through the CMDP-within-online framework to establish the first provable guarantees in this important setting. We obtain task-averaged regret bounds for the reward maximization (optimality gap) and constraint violations using gradient-based meta-learning and show that the task-averaged optimality gap and constraint satisfaction improve with task-similarity in a static environment or task-relatedness in a dynamic environment. Several technical challenges arise when making this framework practical. To this end, we propose a meta-algorithm that performs inexact online learning on the upper bounds of within-task optimality gap and constraint violations estimated by off-policy stationary distribution corrections. Furthermore, we enable the learning rates to be adapted for every task and extend our approach to settings with a competing dynamically changing oracle. Finally, experiments are conducted to demonstrate the effectiveness of our approach.
O NEAR MISS MATERNO EM UMA MATERNIDADE PÚBLICA, ASPECTOS CLÍNICOS E EPIDEMIOLÓGICOS
Creators: name: DARZE, OMAR ISMAIL SANTOS PEREIRA
name: Tanise Oliveira Matos dos Santos
Publisher: name: Zenodo
Year: 2024

description: Trabalho apresentado na 29a Jornada Brasileira de Ginecologia e Obstetricia sobre o near miss materno
Additional file 1 of Mutation landscape in Chinese nodal diffuse large B-cell lymphoma by targeted next generation sequencing and their relationship with clinicopathological characteristics
Creators: name: Cao, Bing
name: Sun, Chenbo
name: Bi, Rui
name: Liu, Zebing
name: Jia, Yijun
name: Cui, Wenli
name: Sun, Menghong
name: Yu, Baohua
name: Li, Xiaoqiu
name: Zhou, Xiaoyan
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 1.
In vivo epigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles
Creators: name: Xiaoyan Lu
name: Miousse, Isabelle R.
name: Pirela, Sandra V.
name: Jodene K. Moore
name: Melnyk, Stepan
name: Koturbash, Igor
name: Demokritou, Philip
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Evidence continues to grow on potential environmental health hazards associated with engineered nanomaterials (ENMs). While the geno- and cytotoxic effects of ENMs have been investigated, their potential to target the epigenome remains largely unknown. The aim of this study is two-fold: 1) determining whether or not industry relevant ENMs can affect the epigenome in vivo and 2) validating a recently developed in vitro epigenetic screening platform for inhaled ENMs. Laser printer-emitted engineered nanoparticles (PEPs) released from nano-enabled toners during consumer use and copper oxide (CuO) were chosen since these particles induced significant epigenetic changes in a recent in vitro companion study. In this study, the epigenetic alterations in lung tissue, alveolar macrophages and peripheral blood from intratracheally instilled mice were evaluated. The methylation of global DNA and transposable elements (TEs), the expression of the DNA methylation machinery and TEs, in addition to general toxicological effects in the lung were assessed. CuO exhibited higher cell-damaging potential to the lung, while PEPs showed a greater ability to target the epigenome. Alterations in the methylation status of global DNA and TEs, and expression of TEs and DNA machinery in mouse lung were observed after exposure to CuO and PEPs. Additionally, epigenetic changes were detected in the peripheral blood after PEPs exposure. Altogether, CuO and PEPs can induce epigenetic alterations in a mouse experimental model, which in turn confirms that the recently developed in vitro epigenetic platform using macrophage and epithelial cell lines can be successfully utilized in the epigenetic screening of ENMs.
Formulation, optimization and characterization of cationic polymeric nanoparticles of mast cell stabilizing agent using the Box–Behnken experimental design
Creators: name: Balaram Gajra
name: Patel, Ravi R.
name: Chintan Dalwadi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Biotechnology
subject: Pharmacology
subject: Cell Biology
subject: Medicine
subject: Engineering
subject: Biochemistry
subject: Biophysics

description: Objective: The present research work was intended to develop and optimize sustained release of biodegradable chitosan nanoparticles (CSNPs) as delivery vehicle for sodium cromoglicate (SCG) using the circumscribed Box–Behnken experimental design (BBD) and evaluate its potential for oral permeability enhancement.Methods: The 3-factor, 3-level BBD was employed to investigate the combined influence of formulation variables on particle size and entrapment efficiency (%EE) of SCG-CSNPs prepared by ionic gelation method. The generated polynomial equation was validated and desirability function was utilized for optimization. Optimized SCG-CSNPs were evaluated for physicochemical, morphological, in-vitro characterizations and permeability enhancement potential by ex-vivo and uptake study using CLSM.Results: SCG-CSNPs exhibited particle size of 200.4 ± 4.06 nm and %EE of 62.68 ± 2.4% with unimodal size distribution having cationic, spherical, smooth surface. Physicochemical and in-vitro characterization revealed existence of SCG in amorphous form inside CSNPs without interaction and showed sustained release profile. Ex-vivo and uptake study showed the permeability enhancement potential of CSNPs.Conclusions: The developed SCG-CSNPs can be considered as promising delivery strategy with respect to improved permeability and sustained drug release, proving importance of CSNPs as potential oral delivery system for treatment of allergic rhinitis. Hence, further studies should be performed for establishing the pharmacokinetic potential of the CSNPs.