cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Use of mobile device technology to continuously collect patient-reported symptoms during radiation therapy for head and neck cancer: A prospective feasibility study
Creators: name: Weiss, J.M.
name: Hayes, D.N.
name: Falchook, A.D.
name: Snavely, A.C.
name: Basch, E.M.
name: Fleming, M.E.
name: Grilley-Olson, J.E.
name: Noe, J.F.
name: Tracton, G.
name: Chera, B.S.
name: Reeve, B.B.
name: Stravers, L.
Publisher: name: Elsevier Inc.
Year: 2016

description: Purpose: Accurate assessment of toxicity allows for timely delivery of supportive measures during radiation therapy for head and neck cancer. The current paradigm requires weekly evaluation of patients by a provider. The purpose of this study is to evaluate the feasibility of monitoring patient reported symptoms via mobile devices. Methods and materials: We developed a mobile application for patients to report symptoms in 5 domains using validated questions. Patients were asked to report symptoms using a mobile device once daily during treatment or more often as needed. Clinicians reviewed patient-reported symptoms during weekly symptom management visits and patients completed surveys regarding perceptions of the utility of the mobile application. The primary outcome measure was patient compliance with mobile device reporting. Compliance is defined as number of days with a symptom report divided by number of days on study. Results: There were 921 symptom reports collected from 22 patients during treatment. Median reporting compliance was 71% (interquartile range, 45%-80%). Median number of reports submitted per patient was 34 (interquartile range, 21-53). Median number of reports submitted by patients per week was similar throughout radiation therapy and there was significant reporting during nonclinic hours. Patients reported high satisfaction with the use of mobile devices to report symptoms. Conclusions: A substantial percentage of patients used mobile devices to continuously report symptoms throughout a course of radiation therapy for head and neck cancer. Future studies should evaluate the impact of mobile device symptom reporting on improving patient outcomes.
(500398) Janes Dore
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Finite-size scaling, dynamic fluctuations, and hyperscaling relation in the Kuramoto model
Creators: name: Hong, Hyunsuk
name: Chaté, Hugues
name: Tang, Lei-Han
name: Park, Hyunggyu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We revisit the Kuramoto model to explore the finite-size scaling (FSS) of the order parameter and its dynamic fluctuations near the onset of the synchronization transition, paying particular attention to effects induced by the randomness of the intrinsic frequencies of oscillators. For a population of size $N$, we study two ways of sampling the intrinsic frequencies according to the {\it same} given unimodal distribution $g(ω)$. In the `{\em random}' case, frequencies are generated independently in accordance with $g(ω)$, which gives rise to oscillator number fluctuation within any given frequency interval. In the `{\em regular}' case, the $N$ frequencies are generated in a deterministic manner that minimizes the oscillator number fluctuations, leading to quasi-uniformly spaced frequencies in the population. We find that the two samplings yield substantially different finite-size properties with clearly distinct scaling exponents. Moreover, the hyperscaling relation between the order parameter and its fluctuations is valid in the regular case, but is violated in the random case. In this last case, a self-consistent mean-field theory that completely ignores dynamic fluctuations correctly predicts the FSS exponent of the order parameter but not its critical amplitude.
Statewide geographic variation in outcomes for adults with acute myeloid leukemia in North Carolina
Creators: name: Zhou, L.
name: Basch, E.M.
name: Wood, W.A.
name: Smitherman, A.B.
name: Meyer, A.-M.
name: Freeman, A.T.
name: Shea, T.C.
Publisher: name: John Wiley and Sons Inc
Year: 2016

description: BACKGROUND: Population-based studies have demonstrated survival disparities related to socioeconomic factors for patients with acute myeloid leukemia (AML). The objective of the current study was to determine whether the local health care infrastructure, represented by Area Health Education Centers (AHEC) region, or treating center experience, represented by National Cancer Institute Comprehensive Cancer Center (NCICCC) designation, were associated with outcomes among patients with AML in North Carolina. METHODS: Patients who were diagnosed with AML from 2003 to 2009 were identified using the University of North Carolina Lineberger Integrated Cancer Information and Surveillance System, a database linking insurance claims to the North Carolina Cancer Registry. A Cox proportional-hazards model was used to explore survival based on AHEC region. A subset of patients who received inpatient chemotherapy was examined to evaluate the impact of treatment at an NCICCC. RESULTS: Nine hundred patients were identified in the study period, 553 of whom received inpatient chemotherapy therapy within 30 days of diagnosis. Almost one-half of these patients (n5294) received chemotherapy at a non-NCICCC. Among the patients who received intensive inpatient therapy, residence in 3 of 9 AHEC regions was associated with a higher risk of mortality (hazard ratio: range, 1.97-4.03; P<.01) at 1 year in multivariate analysis. Treatment at a non-NCICCC was not associated with an increased risk of mortality at 1 year (hazard ratio, 1.25; 95% confidence interval, 0.95-1.65). CONCLUSIONS: Survival among patients with AML in North Carolina varies according to geographic region. Further examination of local practice and referral patterns may inform strategies to improve AML outcomes across the state.
(500399) Elizabeth Sainsbury
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
ЗООЛОГИЯ ДАРСЛАРИНИ ТАШКИЛ ҚИЛИШДА МАҲАЛЛИЙ КЎРГАЗМАЛИ ЖИҲОЗЛАРНИ ТАЙЁРЛАШ УСУЛЛАРИДАН ФОЙДАЛАНИШ УСЛУЛЛАРИ
Creators: name: Рахмонов, Рашит
name: Шоимова, Нигина
Publisher: name: Zenodo
Year: 2025

description: Мақолада биология фанларини ўқитишда кўргазмали жиҳозлардан фойдаланиш ўқувчиларнинг фанга бўлган қизиқишини ошириши, мавзуларни чуқурроқ англаш ва тажрибавий кўникмаларни ривожлантиришга хизмат қилади. Умуртқали ва умуртқасизлар зоологияси фанини ўқитишда маҳаллий ҳудуд материаллари асосида йиғилган намуналарни лаборатория шароитида қўлда тайёрлашнинг иқтисодий самарадорлиги ва афзалликлари ҳақида маълумотлар келтирилган.
WISE J061213.85-303612.5: a new T-dwarf binary candidate
Creators: name: Huélamo, N.
name: Ivanov, V. D.
name: Kurtev, R.
name: Girard, J. H.
name: Borissova, J.
name: Mawet, D.
name: Muzic, K.
name: Cáceres, C.
name: Melo, C. H. F.
name: Sterzik, M. F.
name: Minniti, D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: T and Y-dwarfs are among the coolest and least luminous objects detected, and they can help to understand the properties of giant planets. Their multiplicity properties can shed light on the formation process. We observed a sample six T dwarfs and one L9 dwarf with the Laser Guide Star (LGS) and NAOS-CONICA, the adaptive optics (AO) facility, and the near infrared camera at the ESO Very Large Telescope. From the seven observed objects, we have identified a subarcsecond binary system, WISE J0612-3036, composed of two similar components with spectral types of T6. We measure a separation of $ρ$ = 350$\pm$5 mas and a position angle of $PA = 235\pm1^{\circ}$. Using the mean absolute magnitudes of T6 dwarfs in the 2MASS $JHK_s$ bands, we estimate a distance of $d$=31$\pm$6 pc and derive a projected separation of $ρ$ = 11$\pm$2 au. Another target, WISE J2255-3118, shows a very faint object at 1.3 arcsec in the $K_{\rm s}$ image. The object is marginally detected in $H$, and we derive a near infrared color of $H-K_{\rm s}$$>$ 0.1\,mag. $HST/WFC3$ public archival data reveals that the companion candidate is an extended source.Together with the derived color, this suggests that the source is most probably a background galaxy. The five other sources are apparently single, with 3-$σ$ sensitivity limits between $H$=19-21 for companions at separations $\geq$ 0.5 arcsec. WISE 0612-3036 is probably a new T-dwarf binary composed of two T6 dwarfs. As in the case of other late T-dwarf binaries, it shows a mass ratio close to 1, although its projected separation, $\sim$11 au, is larger than the average ($\sim$ 5 au). Additional observations are needed to confirm that the system is bound.
description: 8 pages, 7 figures, A&A, matches published version
Understanding and Engineering the Stereoselectivity of Humulene Synthase
Creators: name: Schotte, Carsten
name: Lukat, Peer
name: Deuschmann, Adrian
name: Blankenfeldt, Wulf
name: Cox, Russell J.
Publisher: name: Weinheim : Wiley-VCH
Year: 2021
Subjects: subject: biosynthesis
subject: enzyme engineering
subject: humulene
subject: meroterpenoid
subject: tropolone sesquiterpenoid
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: The non-canonical terpene cyclase AsR6 is responsible for the formation of 2E,6E,9E-humulene during the biosynthesis of the tropolone sesquiterpenoid (TS) xenovulene A. The structures of unliganded AsR6 and of AsR6 in complex with an in crystallo cyclized reaction product and thiolodiphosphate reveal a new farnesyl diphosphate binding motif that comprises a unique binuclear Mg2+-cluster and an essential K289 residue that is conserved in all humulene synthases involved in TS formation. Structure-based site-directed mutagenesis of AsR6 and its homologue EupR3 identify a single residue, L285/M261, that controls the production of either 2E,6E,9E- or 2Z,6E,9E-humulene. A possible mechanism for the observed stereoselectivity was investigated using different isoprenoid precursors and results demonstrate that M261 has gatekeeping control over product formation.
(500400) Elizabeth Fielder
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Using patient-reported outcome measures as quality indicators in routine cancer care
Creators: name: Basch, E.M.
name: Stover, A.M.
Publisher: name: John Wiley and Sons Inc.
Year: 2016

description: Historically, patient-reported outcome measures assessing symptoms and physical functioning have not been included in quality-of-care assessments. This editorial accompanies Smith et al's article on the innovative Patient Reported Outcomes Symptoms and Side Effects Study methodology using the Commission on Cancer's Rapid Quality Reporting System, and it explores methodological advancements needed before patient-reported outcome measures can be used as quality-of-care metrics.
Reply to K. Kroenke et al
Creators: name: Basch, E.M.
Publisher: name: American Society of Clinical Oncology
Year: 2016

description: We thank Kroenke and Cheville for their thoughtful letter and appreciate their endorsement of our study and findings. We agree with them that, in our study, patient reporting of symptoms was not the sole driver of improved clinical outcomes. As we describe in the article, our intervention was a composite that also included automated e-mail alerts to clinicians for severe or worsening patient-reported symptoms and printed symptom reports at visits. Symptom monitoring via this approach is likely part of a complex cascade of events including clinician actions that ultimately leads to improved downstream patient outcomes. Indeed, we found that nurses responded to e-mail alerts with clinical actions 77% of the time.
First determination of the $CP$ content of $D \to π^+π^-π^+π^-$ and updated determination of the $CP$ contents of $D \to π^+π^-π^0$ and $D \to K^+K^-π^0$
Creators: name: Malde, S.
name: Thomas, C.
name: Wilkinson, G.
name: Naik, P.
name: Prouve, C.
name: Rademacker, J.
name: Libby, J.
name: Nayak, M.
name: Gershon, T.
name: Briere, R. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Quantum-correlated $ψ(3770) \to D\bar{D}$ decays collected by the CLEO-c experiment are used to perform a first measurement of $F_+^{4π}$, the fractional $CP$-even content of the self-conjugate decay $D \to π^+π^-π^+π^-$, obtaining a value of $0.737 \pm 0.028$. An important input to the measurement comes from the use of $D \to K^0_{\rm S}π^+π^-$ and $D \to K^0_{\rm L}π^+π^-$ decays to tag the signal mode. This same technique is applied to the channels $D \toπ^+π^-π^0$ and $D \to K^+K^-π^0$, yielding $F_+^{πππ^0} = 1.014 \pm 0.045 \pm 0.022$ and $F_+^{KKπ^0} = 0.734 \pm 0.106 \pm 0.054$, where the first uncertainty is statistical and the second systematic. These measurements are consistent with those of an earlier analysis, based on $CP$-eigenstate tags, and can be combined to give values of $F_+^{πππ^0} = 0.973 \pm 0.017$ and $F_+^{KKπ^0} = 0.732 \pm 0.055$. The results will enable the three modes to be included in a model-independent manner in measurements of the unitarity triangle angle $γ$ using $B^\mp \to DK^\mp$ decays, and in time-dependent studies of $CP$ violation and mixing in the $D\bar{D}$ system.
description: Minor revisions following journal acceptance
Gynecologic cancer outcomes in the elderly poor: A population-based study
Creators: name: Meng, K.
name: Basch, E.M.
name: Doll, K.M.
name: Brewster, W.R.
name: Gehrig, P.A.
name: Meyer, A.-M.
Publisher: name: John Wiley and Sons Inc.
Year: 2015

description: BACKGROUND Adults aged ≥65 years who are dually enrolled in Medicare and Medicaid are an at-risk group in health care. However, to the best of the authors' knowledge, the outcomes of women with gynecologic cancers in this population are unknown. METHODS The current study was a population-based cohort study of North Carolina state cancer registry cases of uterine, ovarian, cervical, and vulvar/vaginal cancers (2003-2009), with linked enrollment in Medicare and state Medicaid. Outcomes of all-cause mortality and stage of disease at the time of diagnosis were analyzed as a function of enrollment status using multivariate analysis and survival curves. RESULTS Of 4522 women aged ≥65 years (3702 of whom were enrolled in Medicare [82%] and 820 of whom were dually enrolled [18%]), there were 2286 cases of uterine (51%), 1587 cases of ovarian (35%), 302 cases of cervical (7%), and 347 cases of vulvar/vaginal (8%) cancers. Dual enrollees had increased all-cause mortality overall (adjusted hazard ratio [aHR], 1.34; 95% confidence interval [95% CI], 1.19-1.49), and within each cancer site (uterine: aHR, 1.22 [95% CI, 1.02-1.47]; ovarian: aHR, 1.25 [95% CI, 1.05-1.49]; cervical: aHR, 1.34 [95% CI, 0.96-1.87]; and vulvar/vaginal: aHR, 1.93 [95% CI, 1.36-2.72]). Increased odds of advanced-stage disease at the time of diagnosis among dual enrollees was only present in patients with uterine cancer (adjusted odds ratio, 1.38; 95% CI, 1.06-1.79). Stratified survival curves demonstrated the strongest disparities among women with early-stage uterine and early-stage vulvar/vaginal cancers. CONCLUSIONS Women aged ≥65 years who were dually enrolled in Medicare and Medicaid were found to have an overall 34% increase in all-cause mortality after diagnosis with a gynecologic cancer compared with the non-dually enrolled Medicare population. Women with early-stage uterine and vulvar/vaginal cancers appeared to have the most disparate outcomes. Because these malignancies are generally curable, they have the most potential for benefit from targeted interventions.
Toward patient-centered drug development in oncology
Creators: name: Basch, E.M.
Publisher: name: Massachussetts Medical Society
Year: 2013

description: As an oncologist, when I sit with patients to discuss starting a new chemotherapy regimen, their first questions are often “How will it make me feel?” and “How did patients like me feel with this treatment?” Regrettably, this information is generally missing from U.S. drug labels and from published reports of clinical trials — the two information sources most commonly available to people trying to understand the clinical effects of cancer drugs.
Systematic collection of patient-reported adverse drug reactions: A path to patient-centred pharmacovigilance
Creators: name: Basch, E.M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Over the past 15 years, evidence has mounted that patient self-reporting of symptomatic adverse drug reactions is both feasible and informative. Multiple recent reports have described programmes internationally in which patient self-reports provide data beyond reporting by health professionals. Various models have been used and there are several essential lessons to be learned from these experiences, in addition to work using patient-reported data in related contexts such as clinical trials and routine clinical practice.
(500394) Margaret Annells
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Concurrent material and structure optimization of multiphase hierarchical systems within a continuum micromechanics framework
Creators: name: Gangwar, Tarun
name: Schillinger, Dominik
Publisher: name: Berlin ; Heidelberg ; New York : Springer
Year: 2021
Subjects: subject: Concurrent design
subject: Continuum micromechanics
subject: Hierarchical systems
subject: Homogenization
subject: Multiphase topology optimization
subject: Sensitivity analysis
subject: Dewey Decimal Classification::500 | Naturwissenschaften::510 | Mathematik

description: We present a concurrent material and structure optimization framework for multiphase hierarchical systems that relies on homogenization estimates based on continuum micromechanics to account for material behavior across many different length scales. We show that the analytical nature of these estimates enables material optimization via a series of inexpensive “discretization-free” constraint optimization problems whose computational cost is independent of the number of hierarchical scales involved. To illustrate the strength of this unique property, we define new benchmark tests with several material scales that for the first time become computationally feasible via our framework. We also outline its potential in engineering applications by reproducing self-optimizing mechanisms in the natural hierarchical system of bamboo culm tissue.
(500395) Sarah A Raymond
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(500396) Catherine Pritchard
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A prospective study of the feasibility and acceptability of a Web-based, electronic patient-reported outcome system in assessing patient recovery after major gynecologic cancer surgery
Creators: name: Leitao Jr., M.M.
name: Basch, E.M.
name: Barakat, R.R.
name: Einstein, M.H.
name: Chi, D.S.
name: Andikyan, V.
name: Abu-Rustum, N.R.
name: Rezk, Y.
name: Gualtiere, G.
name: Sonoda, Y.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Purpose: The purposes of this study are to evaluate the feasibility of capturing patient-reported outcomes (PROs) electronically and to identify the most common distressing symptoms in women recovering from major gynecologic cancer surgery. Methods: This was a prospective, single-arm pilot study. Eligible participants included those scheduled for a laparotomy for presumed or known gynecologic malignancy. Patients completed a Web-based STAR (Symptom Tracking and Reporting for Patients) questionnaire once preoperatively and weekly during the 6-week postoperative period. The questionnaire consisted of the patient adaptation of the NCI CTCAE 3.0 and EORTC QLQ-C30 3.0. When a patient submitted a response that was concerning, an automated email alert was sent to the clinician. The patient's assessment of STAR's usefulness was measured via an exit survey. Results: Forty-nine patients completed the study. The procedures included the following: hysterectomy ± staging (67%), resection of tumor (22%), salpingo-oophorectomy (6%), and other (4%). Most patients (82%) completed at least 4 sessions in STAR. The CTC generated 43 alerts. These alerts resulted in 25 telephone contacts with patients, 2 ER referrals, one new appointment, and one pharmaceutical prescription. The 3 most common patient-reported symptoms generating an alert were as follows: poor performance status (19%), nausea (18%), and fatigue (17%). Most patients found STAR useful (80%) and would recommend it to others (85%). Conclusion: Application of a Web-based, electronic STAR system is feasible in the postoperative period, highly accepted by patients, and warrants further study. Poor performance status, nausea, and fatigue were the most common distressing patient-reported symptoms.
Assuring the patient centeredness of patient-reported outcomes: Content validity in medical product development and comparative effectiveness research
Creators: name: Reeve, B.B.
name: Basch, E.
name: Abernethy, A.P.
Publisher: name: Elsevier Ltd
Year: 2011

description: Not all patient-reported outcomes are patient-centered, and not all patient-centered outcomes are patient-reported. The essential characteristic of a patient-centered approach to outcome measurement is that it assesses concepts (i.e., health-related phenomena) that are considered most important by members of a given target population, based on direct input from representatives of that population. Concepts for measurement should not be selected based solely on convenience or interest to investigators. Patient-centered patient-reported outcome measures must meet this criterion and also be meaningful and comprehensible to members of a population when administered, including among those with diverse racial/cultural backgrounds and lower educational/literacy levels.
Metered energy savings and pay-for-performance schemes: Why now?
Creators: name: Santini, Marion
Publisher: name: Zenodo
Year: 2023
Subjects: Energy efficiency
Renovation Wave
Energy transition
Refurbishment
Energy efficiency directive

description: This booklet sets the context for the relevance and importance of prioritizing initiatives to increase investments in energy efficiency refurbishment projects, for instance through innovative business schemes such as Pay-for-Performance programmes.
Search for production of $WW/WZ$ resonances decaying to a lepton, neutrino and jets in $pp$ collisions at $\sqrt{s}$ = 8 TeV with the ATLAS detector
Creators: name: ATLAS Collaboration
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search is presented for narrow diboson resonances decaying to $WW$ or $WZ$ in the final state where one $W$ boson decays leptonically (to an electron or a muon plus a neutrino) and the other $W/Z$ boson decays hadronically. The analysis is performed using an integrated luminosity of 20.3 fb$^{-1}$ of $pp$ collisions at $\sqrt{s}$ = 8 TeV collected by the ATLAS detector at the LHC. No evidence for resonant diboson production is observed, and resonance masses below 700 GeV and 1490 GeV are excluded at 95% confidence level for the spin-2 Randall-Sundrum bulk graviton $G^*$ with coupling constant of 1.0 and the extended gauge model $W'$ boson respectively.
description: 12 pages plus author list + cover pages (29 pages total), 2 figures, 1 table, submitted to EPJC, All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/EXOT-2013-01/ Erratum: DOI: 10.1140/epjc/s10052-015-3593-4: http://dx.doi.org/10.1140/epjc/s10052-015-3593-4
The missing voice of patients in drug-safety reporting
Creators: name: Basch, E.M.
Publisher: name: Massachussetts Medical Society
Year: 2010

description: A patient wants to know about symptoms she may have from a prescription drug she is taking. Consulting the label’s “Adverse Reactions” section, she finds a wealth of data. Little does she realize that this information, largely collected during clinical trials, is based almost entirely on clinicians’ impressions of patients’ symptoms — not on patients’ own firsthand reports of their experiences with the drug.
Reverse Hardy-type inequalities for supremal operators with measures
Creators: name: Mustafayev, R. Ch.
name: Ünver, T.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: In this paper we characterize the validity of the inequalities $\|g\|_{p,(a,b),λ} \le c \|u(x) \|g\|_{\infty,(x,b),μ}\|_{q,(a,b),ν}$ and $\label{eq.0.1.2} \|g\|_{p,(a,b),λ} \le c \|u(x) \|g\|_{\infty,(a,x),μ}\|_{q,(a,b),ν} $ for all non-negative Borel measurable functions $g$ on the interval $(a,b)$, where $0 < p \le +\infty$, $0 < q \le +\infty$, $λ$, $μ$ and $ν$ are non-negative Borel measures on $(a,b)$, and $u$ is a weight function on $(a,b)$.
description: Accepted in Mathematical Inequalities & Applications
The Development of Problem-Solving Ability, Academic Achievement, and Attitude toward Science Using Flipped Classroom Approach of 1oth Grade Student
Creators: name: Kanokwan Kumhla
Publisher: name: DR.KEN Institute of Academic Development and Promotion.
Year: 2023
Subjects: Flipped Classroom
Ability to Solve Scientific Problems
Attitude towards Science

description: Interdisciplinary Academic and Research Journal, 3, 5, 531-548
(500393) George Corps
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Some Entropy Bump Conditions for Fractional Maximal and Integral Operators
Creators: name: Rahm, Robert
name: Spencer, Scott
Publisher: name: arXiv
Year: 2015
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: We investigate weighted inequalities for fractional maximal operators and fractional integral operators. We work within the innovative framework of "entropy bounds" introduced by Treil--Volberg. Using techniques developed by Lacey and the second author, we are able to efficiently prove the weighted inequalities.
description: v2. Part of Theorem 1.1 from v1 was not true; we fixed the error. We thank Kabe Moen for pointing this out to us
(500390) James Masters
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Validation study of a web-based assessment of functional recovery after radical prostatectomy
Creators: name: Eastham, J.A.
name: Scardino, P.T.
name: Shouery, M.
name: Vickers, A.J.
name: Savage, C.J.
name: Basch, E.M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Background: Good clinical care of prostate cancer patients after radical prostatectomy depends on careful assessment of post-operative morbidities, yet physicians do not always judge patient symptoms accurately. Logistical problems associated with using paper questionnaire limit their use in the clinic. We have implemented a web-interface ("STAR") for patient-reported outcomes after radical prostatectomy.Methods: We analyzed data on the first 9 months of clinical implementation to evaluate the validity of the STAR questionnaire to assess functional outcomes following radical prostatectomy. We assessed response rate, internal consistency within domains, and the association between survey responses and known predictors of sexual and urinary function, including age, time from surgery, nerve sparing status and co-morbidities.Results: Of 1581 men sent an invitation to complete the instrument online, 1235 responded for a response rate of 78%. Cronbach's alpha was 0.84, 0.86 and 0.97 for bowel, urinary and sexual function respectively. All known predictors of sexual and urinary function were significantly associated with survey responses in the hypothesized direction.Conclusions: We have found that web-based assessment of functional recovery after radical prostatectomy is practical and feasible. The instrument demonstrated excellent psychometric properties, suggested that validity is maintained when questions are transferred from paper to electronic format and when patients give responses that they know will be seen by their doctor and added to their clinic record. As such, our system allows ready implementation of patient-reported outcomes into routine clinical practice.
Semistability and Simple Connectivity at Infinity of Finitely Generated Groups with a Finite Series of Commensurated Subgroups
Creators: name: Mihalik, Michael
Publisher: name: arXiv
Year: 2014
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics

description: A subgroup $H$ of a group $G$ is $commensurated$ in $G$ if for each $g\in G$, $gHg^{-1}\cap H$ has finite index in both $H$ and $gHg^{-1}$. If there is a sequence of subgroups $H=Q_0\prec Q_1\prec ...\prec Q_{k}\prec Q_{k+1}=G$ where $Q_i$ is commensurated in $Q_{i+1}$ for all $i$, then $Q_0$ is $subcommensurated$ in $G$. In this paper we introduce the notion of the simple connectivity at infinity of a finitely generated group (in analogy with that for finitely presented groups). Our main result is: If a finitely generated group $G$ contains an infinite, finitely generated, subcommensurated subgroup $H$, of infinite index in $G$, then $G$ is 1-ended and semistable at $\infty$. If additionally, $H$ is finitely presented and 1-ended, then $G$ is simply connected at $\infty$. A normal subgroup of a group is commensurated, so this result is a strict generalization of a number of results, including the main theorems of G. Conner and M. Mihalik \cite{CM}, B. Jackson \cite{J}, V. M. Lew \cite{L}, M. Mihalik \cite{M1}and \cite{M2}, and J. Profio \cite{P}.
description: 21 pages, 3 figures. arXiv admin note: text overlap with arXiv:1201.2965
(500392) Elizabeth Marlow
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Prognostic value of symptom burden for overall survival in patients receiving chemotherapy for advanced nonsmall cell lung cancer
Creators: name: Lu, C.
name: Wang, X.S.
name: Mendoza, T.R.
name: Shi, Q.
name: Mobley, G.M.
name: Cleeland, C.S.
name: Basch, E.M.
name: Johnson, V.E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: BACKGROUND: Patient-reported outcomes have shown independent prognostic value for patients with nonsmall cell lung cancer (NSCLC). However, translating patient-reported outcomes into useful prognostic information for individual patients has been problematic. METHODS: A total of 94 patients with advanced NSCLC and an Eastern Cooperative Oncology Group performance status (PS) of 0 to 2 who qualified for chemotherapy rated symptom severity using the M. D. Anderson Symptom Inventory before and after their first chemotherapy cycle. Prognostic values of baseline symptoms and changes in symptom severity were examined by Cox proportional hazards models. RESULTS: In multivariate analysis, controlled for demographic and other factors, baseline coughing rated ≤4 independently predicted significantly higher risk for shorter survival (hazards ratio [HR], 8.69; P < .0001). Patients with coughing ≤4 and a PS of 2 were more likely to have shorter survival (HR, 20.6; P < .0001) than patients with coughing <4 and a PS of 0 to 1. A 1-point or greater increase in severity of fatigue (P < .05), shortness of breath, or poor appetite (P < .01) from baseline to the end of the first chemotherapy cycle was also found to be independently associated with higher risk for poor survival. CONCLUSIONS: An increased risk for shorter survival was indicated by moderate to severe coughing at baseline or by increased fatigue or shortness of breath during the first chemotherapy cycle in patients with advanced NSCLC. Although cross-validation is needed, these data suggest that an individual patient's symptom severity scores, quickly obtainable in the clinic, might contribute clinically useful information for treatment planning for that patient.
О ВЛИЯНИИ   ХИМИЧЕСКИХ  ДОБАВОК НА СВОЙСТВА ГИПСОВОГО ВЯЖУЩЕГО
Creators: name: Рузметов, Фазлиддин
name: Амиров, Темирбек
name: Тошев, Нодир
Publisher: name: Zenodo
Year: 2023

description: При использовании химических добавок способствует повышению прочности и водостойкости гипсового вяжущего, снижает водопроницаемость. Правильный подбор количества химических добавок очень важен для улучшения свойств гипсового вяжущего.
Department of Defense prostate cancer clinical trials consortium: A new instrument for prostate cancer clinical research
Creators: name: Kantoff, P.
name: Morris, M.J.
name: George, D.
name: Wilding, G.
name: Carducci, M.A.
name: Basch, E.M.
name: Slovin, S.E.
name: Small, E.J.
name: Oh, W.K.
name: Mathew, P.
name: Logothetis, C.
name: Hussain, M.
name: Ryan, C.
name: Higano, C.
name: Beer, T.M.
name: Scher, H.I.
Publisher: name: Elsevier Inc.
Year: 2009

description: Background: In 2005, the US Department of Defense, through the US Army Medical Research and Materiel Command, Office of the Congressionally Directed Medical Research Programs, created a funding mechanism to form a clinical trials consortium to conduct phase I and II studies in prostate cancer. This is the first report of the Prostate Cancer Clinical Trials Consortium (PCCTC). Patients and Methods: The Department of Defense award supports a consortium of 10 prostate cancer research centers. Memorial Sloan-Kettering Cancer Center was awarded the Coordinating Center grant for the consortium and charged with creating an infrastructure to conduct early-phase multicenter clinical trials. Each participating center was required to introduce ≥ 1 clinical trial per year and maintain accrual of a minimum of 35 patients per year. Results: The PCCTC was launched in 2006 and now encompasses 10 leading prostate cancer research centers. Fifty-one trials have been opened, and 1386 patients have been accrued at member sites. Members share an online clinical trial management system for protocol tracking, electronic data capture, and data storage. A legal framework has been instituted, and standard operating procedures, an administrative structure, editorial support, centralized budgeting, and mechanisms for scientific review are established. Conclusion: The PCCTC fulfills a congressional directive to create a clinical trials instrument dedicated to early-phase prostate cancer studies. The member institutions have built an administrative, informatics, legal, financial, statistical, and scientific infrastructure to support this endeavor. Clinical trials are open and accruing in excess of federally mandated goals.
Variation in Adherence to External Beam Radiotherapy Quality Measures Among Elderly Men With Localized Prostate Cancer
Creators: name: Basch, E.M.
name: Jang, T.L.
name: Schrag, D.
name: Zelefsky, M.J.
name: Bekelman, J.E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Purpose: To characterize the variation in adherence to quality measures of external beam radiotherapy (EBRT) for localized prostate cancer and its relation to patient and provider characteristics in a population-based, representative sample of U.S. men. Methods and Materials: We evaluated EBRT quality measures proposed by a RAND expert panel of physicians among men aged ≥65 years diagnosed between 2000 and 2002 with localized prostate cancer and treated with primary EBRT using data from the linked Surveillance, Epidemiology, and End Results (SEER)-Medicare program. We assessed the adherence to five EBRT quality measures that were amenable to analysis using SEER-Medicare data: (1) use of conformal RT planning; (2) use of high-energy (>10-MV) photons; (3) use of custom immobilization; (4) completion of two follow-up visits with a radiation oncologist in the year after therapy; and (5) radiation oncologist board certification. Results: Of the 11,674 patients, 85% had received conformal RT planning, 75% had received high-energy photons, and 97% had received custom immobilization. One-third of patients had completed two follow-up visits with a radiation oncologist, although 91% had at least one visit with a urologist or radiation oncologist. Most patients (85%) had been treated by a board-certified radiation oncologist. Conclusions: The overall high adherence to EBRT quality measures masked substantial variation in geography, socioeconomic status in the area of residence, and teaching affiliation of the RT facility. Future research should examine the reasons for the variations in these measures and whether the variation is associated with important clinical outcomes.
Intraoperative assembly of anatomical shoulder prosthesis frequently results in malalignment of the modular taper junction
Creators: name: Herbster, Maria
name: Berth, Alexander
name: Märtens, Nicole
name: Robra, Marcel
name: Welzel, Florian
name: Dallmann, Frank
name: Lohmann, Christoph H.
name: Halle, Thorsten
name: Bertrand, Jessica
name: Döring, Joachim
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2021
Subjects: subject: Assembly force
subject: Impact direction
subject: Modularity
subject: Shoulder arthroplasty
subject: Taper strength
subject: 610.72

description: Anatomical shoulder arthroplasties (ASA) may fail because of micromotion at the modular taper junction causing wear due to fretting. Sufficient taper strength can reduce micromotion and potential reasons for failure. However, there are no normative standards for a safe assembly process performed intraoperatively by the surgeon. The purpose of this study is to determine the effect of common intraoperative assembly strategies and to identify critical influencing factors on taper stability. ASA with standard and stemless humeral component in combination with concentric Al2O3 heads and eccentric CoCr28Mo6 alloyed humeral heads were tested. Taper angles and surface roughness were determined. Force magnitudes and impact directions were recorded using a sensorized head impactor and a threedimensional force measuring platform. Subsequently, the axial pull‐off forces were measured and taper engagement areas were macroscopically evaluated. In comparison to standard stem tapers that were impacted with an assembly device, stemless tapers were impacted into the artificial bone with significantly lower forces. Taper strength correlates to maximum impact force and was higher for CoCr28Mo6 heads with a mean pull‐off ratio of 0.56 than for Al2O3 heads with 0.37. Interestingly, all tapers showed an asymmetric clamping behavior, due to tilting during impaction. This is caused by the variation of the resulting force vector and further promoted by humeral head eccentricity. Assembly technique markedly influences the force magnitude, impact direction, impulse, and consequently taper strength. The resulting force vector and head eccentricity were identified as potential risk factors for taper malalignment.
Fast, Multicore-Scalable, Low-Fragmentation Memory Allocation through Large Virtual Memory and Global Data Structures
Creators: name: Aigner, Martin
name: Kirsch, Christoph M.
name: Lippautz, Michael
name: Sokolova, Ana
Publisher: name: arXiv
Year: 2015
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences
subject: D.4.2; D.3.4

description: We demonstrate that general-purpose memory allocation involving many threads on many cores can be done with high performance, multicore scalability, and low memory consumption. For this purpose, we have designed and implemented scalloc, a concurrent allocator that generally performs and scales in our experiments better than other allocators while using less memory, and is still competitive otherwise. The main ideas behind the design of scalloc are: uniform treatment of small and big objects through so-called virtual spans, efficiently and effectively reclaiming free memory through fast and scalable global data structures, and constant-time (modulo synchronization) allocation and deallocation operations that trade off memory reuse and spatial locality without being subject to false sharing.
A representation-theoretic proof of the branching rule for Macdonald polynomials
Creators: name: Sun, Yi
Publisher: name: arXiv
Year: 2014
Subjects: subject: Representation Theory (math.RT)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 33D52 (primary), 33D80, 20C08 (secondary)

description: We give a new representation-theoretic proof of the branching rule for Macdonald polynomials using the Etingof-Kirillov Jr. expression for Macdonald polynomials as traces of intertwiners of U_q(gl_n). In the Gelfand-Tsetlin basis, we show that diagonal matrix elements of such intertwiners are given by application of Macdonald's operators to a simple kernel. An essential ingredient in the proof is a map between spherical parts of double affine Hecke algebras of different ranks based upon the Dunkl-Kasatani conjecture.
description: 22 pages