title: ÐÐ±ÑÐ°Ð±Ð¾ÑÐºÐ° Ð´Ð°Ð½Ð½ÑÑ Ð¿Ð¾Ð·Ð¸ÑÑÐ¾Ð½Ð½Ð¾-ÑÐ¼Ð¸ÑÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ¾Ð¼Ð¾Ð³ÑÐ°ÑÐ¸Ð¸ Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ SPM 12 Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ¾Ð² Ñ Ð¿Ð°ÑÐ°Ð½Ð¾Ð¸Ð´Ð½Ð¾Ð¹ ÑÐ¾ÑÐ¼Ð¾Ð¹ ÑÐ¸Ð·Ð¾ÑÑÐµÐ½Ð¸Ð¸
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Processing of positron emission tomography using SPM 12 in patients with paranoid schizophrenia
Creators: name: ÐÐ°Ð±ÐºÐ¸Ð½Ð°, ÐÐµÑÐ¾Ð½Ð¸ÐºÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2020
Subjects: Ð¿Ð¾ÑÑÐ¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ°
Ð¿Ð¾Ð·Ð¸ÑÑÐ¾Ð½Ð½Ð¾-ÑÐ¼Ð¸ÑÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ¾Ð¼Ð¾Ð³ÑÐ°ÑÐ¸Ñ
Ð³Ð¸Ð¿Ð¾Ð¼ÐµÑÐ°Ð±Ð¾Ð»Ð¸Ð·Ð¼
Ð³Ð¸Ð¿ÐµÑÐ¼ÐµÑÐ°Ð±Ð¾Ð»Ð¸Ð·Ð¼
ÑÑÐ¿
ÑÐ¸Ð·Ð¾ÑÑÐµÐ½Ð¸Ñ
spm
hsnding
positron emission tomography
hypometabolism
hypermatabolism
rfp
schizophrenia

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¾ÑÐµÐ½ÐºÐµ Ð¸ Ð¾Ð¿ÑÐ¸Ð¼Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¼ÐµÑÐ¾Ð´Ð° Ð²Ð¾ÐºÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° ÐÐ­Ð¢ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¹ Ð³Ð¾Ð»Ð¾Ð²Ð½Ð¾Ð³Ð¾ Ð¼Ð¾Ð·Ð³Ð° Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ¾Ð² Ñ Ð¿Ð°ÑÐ°Ð½Ð¾Ð¸Ð´Ð½Ð¾Ð¹ ÑÐ¾ÑÐ¼Ð¾Ð¹ ÑÐ¸Ð·Ð¾ÑÑÐµÐ½Ð¸Ð¸. ÐÐ°Ð´Ð°ÑÐ¸, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐµÑÐ°Ð»Ð¸ÑÑ Ð² ÑÐ¾Ð´Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ: 1. ÐÐµÑÐµÐ²Ð¾Ð´ ÐÐ­Ð¢-Ð¸Ð·Ð¾Ð±ÑÐ°Ð¶ÐµÐ½Ð¸Ð¹ Ð² ÑÐ½Ð¸Ð²ÐµÑÑÐ°Ð»ÑÐ½ÑÐ¹ ÑÐ¾ÑÐ¼Ð°Ñ Dicom; 2. ÐÐ±ÑÐ°Ð±Ð¾ÑÐºÐ° Ð² Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ðµ SPM12 Ð´Ð²ÑÑ Ð³ÑÑÐ¿Ð¿ Ñ ÑÑÐµÑÐ¾Ð¼ Ð²ÑÐ±ÑÐ°Ð½Ð½ÑÑ ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ²; 3. Ð Ð°ÑÐ¿Ð¸ÑÐ°ÑÑ Ð¾Ð±ÑÑÐ¼ Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸Ð¹ Ñ Ð°Ð½Ð°ÑÐ¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ Ð¿Ð¾Ð·Ð¸ÑÐ¸Ð¹; 4. Ð¡ÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² Ð´Ð²ÑÑ Ð³ÑÑÐ¿Ð¿ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ¾Ð²; 5. Ð¡ÑÐ°ÑÐ¸ÑÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ Ð´Ð°Ð½Ð½ÑÑ. Ð Ð°Ð±Ð¾ÑÐ° Ð±ÑÐ»Ð° Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° Ð½Ð° Ð±Ð°Ð·Ðµ Ð¤ÐÐÐ£ Â«Ð Ð¾ÑÑÐ¸Ð¹ÑÐºÐ¸Ð¹ Ð½Ð°ÑÑÐ½ÑÐ¹ ÑÐµÐ½ÑÑ ÑÐ°Ð´Ð¸Ð¾Ð»Ð¾Ð³Ð¸Ð¸ Ð¸ ÑÐ¸ÑÑÑÐ³Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¹ Ð¸Ð¼ÐµÐ½Ð¸ Ð°ÐºÐ°Ð´ÐµÐ¼Ð¸ÐºÐ° Ð.Ð. ÐÑÐ°Ð½Ð¾Ð²Ð°Â», Ð³Ð´Ðµ Ð±ÑÐ» ÑÐ¾Ð±ÑÐ°Ð½ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»: 6 ÐÐ­Ð¢ ÑÐºÐ°Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ð¹ ÐÐ Ñ 18F-Ð¤ÐÐ. Ð Ð°Ð½Ð°Ð¼Ð½ÐµÐ·Ðµ Ñ Ð¾Ð´Ð½Ð¾Ð³Ð¾ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ° ÑÐ°ÐºÐ¶Ðµ ÑÐºÐ°Ð·Ð°Ð½Ñ Ð±ÑÐµÐ´Ð¾Ð²ÑÐµ Ð³Ð°Ð»Ð»ÑÑÐ¸Ð½Ð°ÑÐ¸Ð¸ (Ð¿Ð°ÑÐ¸ÐµÐ½Ñ X). ÐÐ½Ð°Ð»Ð¸Ð· Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð»ÑÑ Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÑÑÐ°ÑÐ¸ÑÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÐºÐ°ÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð´Ð»Ñ Ð²ÑÑÐ²Ð»ÐµÐ½Ð¸Ñ Ð¾Ð±Ð»Ð°ÑÑÐµÐ¹ Ð³Ð¸Ð¿Ð¾- Ð¸ Ð³Ð¸Ð¿ÐµÑÐ¼ÐµÑÐ°Ð±Ð¾Ð»Ð¸Ð·Ð¼Ð° Ð³Ð»ÑÐºÐ¾Ð·Ñ Ð² ÐÐ. ÐÐ¾ÑÐ»Ðµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð°, Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¾ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ Ð³ÑÑÐ¿Ð¿ ÑÐ¾ Ð·Ð´Ð¾ÑÐ¾Ð²Ð¾Ð¹ (Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ¾Ð¼ X Ð¸ Ð±ÐµÐ· Ð½ÐµÐ³Ð¾). Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð±ÑÐ»Ð° Ð²ÑÑÐ²Ð»ÐµÐ½Ð° Ð½ÐµÐ¾Ð´Ð½Ð¾ÑÐ¾Ð´Ð½Ð¾ÑÑÑ Ð½ÐµÐ¹ÑÐ¾ÑÐ¸Ð·Ð¸Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ñ Ð¼ÐµÑÐ°Ð½Ð¸Ð·Ð¼Ð¾Ð² Ð´Ð»Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ¾Ð², ÑÑÐ¾ ÑÐ²Ð¸Ð´ÐµÑÐµÐ»ÑÑÑÐ²ÑÐµÑ Ð¾ Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼Ð¾ÑÑÐ¸ Ð¿Ð¾Ð´Ð±Ð¾ÑÐ° Ð¸Ð½Ð´Ð¸Ð²Ð¸Ð´ÑÐ°Ð»ÑÐ½Ð¾Ð¹ ÑÐµÑÐ°Ð¿Ð¸Ð¸. ÐÐ»Ñ ÑÐ¾ÑÐ½Ð¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° ÑÑÐµÐ±ÑÐµÑÑÑ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ðµ Ð´Ð¾Ð¿Ð¾Ð»Ð½Ð¸ÑÐµÐ»ÑÐ½ÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¹ Ð½Ð° Ð±Ð¾Ð»ÑÑÐ¸Ñ Ð²ÑÐ±Ð¾ÑÐºÐ°Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ¾Ð². ÐÐ¾Ð»ÑÑÐµÐ½Ð½ÑÐµ Ð´Ð°Ð½Ð½ÑÐµ Ð¼Ð¾Ð³ÑÑ Ð±ÑÑÑ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ñ Ð² Ð´Ð°Ð»ÑÐ½ÐµÐ¹ÑÐ¸Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸ÑÑ Ð² Ð¾Ð±Ð»Ð°ÑÑÐ¸ ÑÐ¸Ð·Ð¾ÑÑÐµÐ½Ð¸Ð¸.
description: The given work is devoted to evaluating and optimizing the method of voxel analysis of PET brain studies in patients with paranoid form of schizophrenia. The research set the following goals: 1. Translation of PET images into the universal Dicom format; 2. The program processes the SPM12 of two groups based on the selected criteria; 3. Chart the volume of changes from anatomical positions; 4. Comparison of the results of two patient groups; 5. Statistical analysis of the data obtained. The work was carried out on the basis of FSBU "Russian Scientific Center of Radiology and Surgical Technologies named after Academician A.M. Granov", where the material was collected: 6 PET scans of GM with 18F-FDG. The history of one patient also indicates delusional hallucinations (patient X). The analysis was performed using statistical parametric mapping to identify regions of hypo- and hypermetabolism glucose in GM. After the analysis, the groups with healthy (with and without patient X) were compared. The study revealed heterogeneity of neurophysiological mechanisms for patients, indicating the need to select individual therapy. Accurate analysis requires additional studies on large patient samples. The findings can be used in further research in schizophrenia.