cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers
Creators: name: Krieg, Stephan
name: Rohde, Thomas
name: Rausch, Tobias
name: Butthof, Luise
name: Wendler-Link, Lena
name: Eckert, Christoph
name: Breuhahn, Kai
name: Galy, Bruno
name: Korbel, Jan
name: Billmann, Maximilian
name: Breinig, Marco
name: Tschaharganeh, Darjus F.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: Additional file 1: Figures S1 – S8.
The Unintended Consequences of Headquarters’ Involvement in Decentralized Transfer Price Negotiations : Experimental Evidence
Creators: name: Elsinger, Florian
name: Rankin, Frederick W.
name: Arnold, Markus Christopher
Publisher: name: (:null)
Year: 2017
Subjects: 330 Economics
650 Management & public relations

description: This study investigates how headquarters involvement affects the efficiency of decentralized transfer price negotiations. Prior research assumes that decentralized managers negotiate transfer prices autonomously. However, evidence suggests that headquarters can become involved in transfer price negotiations, particularly after negotiation failure. While the intention of headquarters involvement is to overcome inefficiencies arising from decentralized managers’ inability to agree on a transfer price, we suggest that such involvement is likely to have the unintended consequences of further reducing both agreement frequency and the efficiency of negotiated transfer pricing. Reduced agreement is likely to occur because decentralized managers are likely to feel less responsible for the negotiation outcome and may be overly optimistic about headquarters’ decision. Reduced efficiency is likely to result because overconfidence is likely to make headquarters underestimate its informational disadvantage compared to decentralized managers and, consequently, induces inefficient transfer decisions. For the same reasons, inefficiency is likely to be the larger, the more decision authority headquarters takes over after negotiation failure. In an experiment, we manipulate whether headquarters involvement is absent vs. present. Nested within headquarters involvement present are two conditions: one where, after negotiation failure, headquarters suggests a transfer price that either decentralized manager can reject (weak involvement) and one where it can impose a price at which they must trade (strong involvement). Consistent with our predictions, we find that headquarters involvement reduces the frequency of negotiation agreement and the efficiency of transfer pricing. Additionally, we find that efficiency is reduced more when headquarters involvement is strong rather than weak. We contribute to the literature on negotiated transfer pricing by providing evidence about headquarters’ biased perceptions of negotiation impasse and the unintended consequences of its involvement. Additionally, our study informs organizations about the benefits of committing to non-involvement in decentralized transfer price negotiations.
Der Hinkende Bot von Bern. 300 Jahre Kalendergeschichte
Creators: name: Wernicke, Norbert D.
name: Pellin, Elio
Publisher: name: (:null)
Year: 2017
Subjects: 830 German & related literatures
430 German & related languages

description: Ausstellung zum 300sten Geburtstag des Volkalenders. 26. Oktober 2017 bis 25. März 2018 in der Bibliothek Münstergasse, Bern.
The Unintended Consequences of Headquarters’ Involvement in Decentralized Transfer Price Negotiations : Experimental Evidence
Creators: name: Arnold, Markus Christopher
name: Elsinger, Florian
name: Rankin, Frederick W.
Publisher: name: (:null)
Year: 2017
Subjects: 650 Management & public relations
330 Economics

description: This study investigates how headquarters involvement affects the efficiency of decentralized transfer price negotiations. Prior research assumes that decentralized managers negotiate transfer prices autonomously. However, evidence suggests that headquarters can become involved in transfer price negotiations, particularly after negotiation failure. While the intention of headquarters involvement is to overcome inefficiencies arising from decentralized managers’ inability to agree on a transfer price, we suggest that such involvement is likely to have the unintended consequences of further reducing both agreement frequency and the efficiency of negotiated transfer pricing. Reduced agreement is likely to occur because decentralized managers are likely to feel less responsible for the negotiation outcome and may be overly optimistic about headquarters’ decision. Reduced efficiency is likely to result because overconfidence is likely to make headquarters underestimate its informational disadvantage compared to decentralized managers and, consequently, induces inefficient transfer decisions. For the same reasons, inefficiency is likely to be the larger, the more decision authority headquarters takes over after negotiation failure. In an experiment, we manipulate whether headquarters involvement is absent vs. present. Nested within headquarters involvement present are two conditions: one where, after negotiation failure, headquarters suggests a transfer price that either decentralized manager can reject (weak involvement) and one where it can impose a price at which they must trade (strong involvement). Consistent with our predictions, we find that headquarters involvement reduces the frequency of negotiation agreement and the efficiency of transfer pricing. Additionally, we find that efficiency is reduced more when headquarters involvement is strong rather than weak. We contribute to the literature on negotiated transfer pricing by providing evidence about headquarters’ biased perceptions of negotiation impasse and the unintended consequences of its involvement. Additionally, our study informs organizations about the benefits of committing to non-involvement in decentralized transfer price negotiations.
Additional file 1 of Compressed sensing 3D T2WI radiomics model: improving diagnostic performance in muscle invasion of bladder cancer
Creators: name: Li, Shuo
name: Fan, Zhichang
name: Guo, Junting
name: Li, Ding
name: Chen, Zeke
name: Zhang, Xiaoyue
name: Wang, Yongfang
name: Li, Yan
name: Yang, Guoqiang
name: Wang, Xiaochun
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Biotechnology
Biological Sciences not elsewhere classified
Cancer

description: Supplementary Material 1
In vivo assessment of muscle membrane properties in the sodium channel myotonias.
Creators: name: Tan, S Veronica
name: Z'Graggen, Werner Josef
name: Hanna, Michael G
name: Bostock, Hugh
Publisher: name: John Wiley & Sons
Year: 2018
Subjects: 610 Medicine & health

description: INTRODUCTION The gain-of-function mutations that underlie sodium channel myotonia (SCM) and paramyotonia congenital (PMC) produce differing clinical phenotypes. We used muscle velocity recovery cycles (MVRCs) to investigate membrane properties. METHODS MVRCs and responses to trains of stimuli were compared in patients with SCM (n = 9), PMC (n = 8), and normal controls (n = 26). RESULTS The muscle relative refractory period was reduced in SCM, consistent with faster recovery of the mutant sodium channels from inactivation. Both SCM and PMC showed an increased early supernormality and increased mean supernormality following multiple conditioning stimuli, consistent with slowed sodium channel inactivation. Trains of fast impulses caused a loss of amplitude in PMC, after which only half of the muscle fibers recovered, suggesting that the remainder stayed depolarized by persistent sodium currents. DISCUSSION The differing effects of mutations on sodium channel function can be demonstrated in human subjects in vivo using this technique. Muscle Nerve, 2017.
title: Fußball im Wandel der Zeit
Creators: name: Niefergall, Alfred
Year: 2010

description: Das Ziel der Arbeit war die physiologischen Veränderungen im Sportspiel Fußball zu beschreiben, sowie Gründe aufzudecken, warum der österreichische Spitzenfußball international an Bedeutung verloren hat. Das Thema wurde auf hermeneutischem und empirischen Weg erarbeitet, wobei ein Interview mit östereichischen Trainern den empirischen Teil bildete und der hermeneutische Teil durch Fachliteratur, Analysen und Studien aufbereitet wurde. Der österreichische unterscheidet sich vom interantionalen Fußball durch das Ausmaß der intensiven Läufe und damit zusammenhängenden technisch/taktischen Gegenheiten. Österreichs Ziel muss es sein sich als Ausbildungsland im Fußball zu deklarieren, da die Möglichkeiten längerfristig auf Klubebene internationale Erfolge zu feiern mehr als gering sind.
description: The aim of this study was to describe the physical changes in soccer, as well as to detect reasons why the Austrian soccer has lost international denotation. The studie has been developed in hermeneutic and empiric way, at which interviews with Austrian coaches represented the empirical part and the hermeneutical part has been prepared with specialist literature, analysis and studies. The Austrian soccer differentiates from the international one in the amount of intensive runs and their belonging conditions. The aim of Austria should be a declaration to develop young players, because the possibilities are more than marginal to celebrate long-term successes in club level.
A Synthetic Acetylation Substrate to Study Gcn5 Targeting and Function in Yeast.
Creators: name: Rossl, Anthony
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2018
Subjects: Gcn5
Acetylation
Targeting
Consensus sequence
Ada3
SILAC
SAGA
Sirtuin

description: Acetylation was previously thought to occur exclusively on histones, but recent high-throughput screens have identified thousands of non-histone substrates. Despite the identification of these sites, little is known about how these acetyltransferase enzymes target their substrates. Gcn5 is the catalytic acetyltransferase found within the highly conserved SAGA complex. Recently, a member of this complex, Ada2, was found to impact Gcn5 substrate selection. In the yeast model organism Saccharomyces cerevisiae, a synthetic substrate developed from a proposed Gcn5-specific consensus sequence is used to identify regulators of Gcn5 substrate selection. This work is the first to demonstrate that addition of a consensus sequence is enough to confer acetylation of a non-substrate. With this method, Ada3 was identified as a key regulator, and acetylome profiling identified novel targets for Gcn5 dependent acetylation specifically regulated by Ada3. This system could be adapted for other acetyltransferases to identify regulators of substrate selection.
Safety of Intra-Articular Gold Microimplants in Horses–A Randomized, Blinded, Controlled Experimental Study
Creators: name: Spadavecchia, Claudia
name: Ramseyer, Alessandra
name: Reichenbach, Stephan
name: Witte, Stefan
name: Märki, Nina
name: Gerber, Vinzenz
name: Kuchen, Stefan
Publisher: name: W.B. Saunders Co.
Year: 2018
Subjects: 360 Social problems & social services
610 Medicine & health
630 Agriculture

description: Arthrogenic pain is a common problem in equids. Frequently used treatments such as systemic non-steroidal anti-inflammatory drugs or intra-articular steroids can lead to severe side effects if used repeatedly. Gold has been used since ancient times to treat a variety of conditions and has anti-inflammatory and immunomodulating properties. Results from clinical and in vitro studies suggest that local gold might provide a safe and effective alternative to alleviate articular pain. In particular, gold microimplants have been proposed to this end, but it is unknown if and how healthy joints react to this treatment. The aim of this study was to evaluate the safety of gold microimplants (Berlock-Micro-Implants) mixed with hyaluronic acid and injected into the middle carpal joint of nine healthy horses. Each horse was treated in one carpus and shamtreated on the contralateral. Lameness, carpal temperature increase, swelling, and reactions to joint palpation were observed in both treated and sham-treated carpi in the first week after needle arthroscopy and treatment. Significant differences between treated and sham-treated carpi were found only for mechanical nociceptive thresholds 4 days after treatment. Higher thresholds were found in treated joints compared with sham-treated joints. None of the outcome measures selected in the present study indicated systemic or local adverse effects specifically attributed to gold microimplants. In the absence of systemic and local adverse reactions to gold microimplants, the results of the present study support future clinical trials to test the pain-relieving efficacy of this treatment modality in subacute or chronic articular inflammatory processes in equine patients.
It Is Not Just About Competition with “Free”: Differences Between Content Formats in Consumer Preferences and Willingness to Pay
Creators: name: Berger, B
name: Matt, C
name: Steininger, D
name: Hess, T
Publisher: name: Taylor & Francis
Year: 2015
Subjects: 000 Computer science, knowledge & systems
330 Economics

description: While consumption of content in offline formats continues to decline, many providers are still struggling to monetize their content online, because consumers’ willingness to pay (WTP) for content in online formats is low. The availability of free content on the Internet is often considered the primary reason for this issue. However, we hold that the lower WTP is also related to a lower appraisal of online formats per se. Using a conjoint analysis and the example of newspaper subscriptions, we explore differences in consumer preferences and WTP between offline and online formats. Our results show that after price, format is the secondmost important attribute of a newspaper subscription. While consumers still prefer the printed newspaper to any online format, WTP differs across online formats and is strongly associated with device ownership. Our study provides a novel understanding of the previously neglected factor content format and its importance for content providers.
How to reduce turnover intention in team sports? Effect of organizational support on turnover intention of professional team sports athletes
Creators: name: Maier, Christopher
name: Ströbel, Tim
name: Woratschek, Herbert
Publisher: name: Emerald Group Publishing Limited
Year: 2018
Subjects: 790 Sports, games & entertainment
330 Economics

description: Turnover of employees is a key challenge for companies. The same is true for sports clubs that must set appropriate incentives to decrease their athletes’ turnover intention. As salary caps and team budgets restrict monetary incentives, the purpose of this paper is to investigate the effect of organizational support on turnover intention of professional team sports athletes. The paper applies a combined approach of qualitative and quantitative research and considers the specific requirements of European professional team sports. First, a qualitative study investigates organizational support in team sports and identifies relevant non-monetary incentives. Second, a quantitative study tests the effects of the identified organizational support incentives on turnover intention using a unique data set of professional team sports athletes. Third, a moderation analysis measures possible effects of age.
Additional file 1 of The potential role of the Asian bush mosquito Aedes japonicus as spillover vector for West Nile virus in the Netherlands
Creators: name: Linthout, Charlotte
name: Martins, Afonso Dimas
name: de Wit, Mariken
name: Delecroix, Clara
name: Abbo, Sandra R.
name: Pijlman, Gorben P.
name: Koenraadt, Constantianus J. M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 1: Table S1. Overview on explanatory variables included in the final GLM for the investigated dependent variables.
Internationales Zivilprozessrecht unter Einbezug der internationalen Schiedsgerichtsbarkeit, Entwicklungen 2015
Creators: name: Kren Kostkiewicz, Jolanta
name: Markus, Alexander
Publisher: name: Stämpfli Verlag
Year: 2016
Subjects: 340 Law

description: Im Bereich der Rechtsetzung werden bereits beschlossene Änderungen sowie Rechtsetzungsprojekte dargelegt. Im Teil über die Rechtsprechung wird insbesondere eine Darstellung der wichtigsten amtlich und nicht amtlich publizierten Bundesgerichtsentscheidungen geboten. Und bezüglich der Literatur wird nicht nur umfassend auf Neuerscheinungen hingewiesen, sondern es werden von ausgewählten Publikationen auch deren Hauptaussagen zusammengefasst. njus.ch ermöglicht den Leserinnen und Lesern, in kürzester Zeit auf den neuesten Stand der Entwicklungen in einem bestimmten Rechtsgebiet zu gelangen.
Enabling the Next Generation of Spaceborne Quadrupole Mass Spectrometers
Creators: name: Zurbuchen, T. H.
name: Gershman, D. J.
name: Benna, M.
name: Mahaffy, P. R.
name: Rubin, Martin
name: Block, B. P.
Publisher: name: American Society of Civil Engineers
Year: 2012
Subjects: 620 Engineering
520 Astronomy

description: The quadrupole mass spectrometer (QMS) has over 30 years of spaceflight heritage in making important neutral gas and low energy ion observations. Given their geometrical constraints, these instruments are currently operated at the extreme limit of their capabilities. However, a technique called higher order auxiliary excitation provides a set of novel, robust, electronics-based solutions for improving the performance of these sensors. By driving the quadrupole rods with an additional frequency nearly twice that of the normal RF operating frequency, substantially increased abundance sensitivity, maximum attainable mass resolution, and peak stability can be achieved through operation of voltage scan lines through the center of formed upper stability islands. Such improvements are modeled using numerical simulations of ion trajectories in a quadrupole field with and without applied higher order auxiliary excitation. When compared to a traditional QMS with a mass range up to 500Da, sensors can be designed with the same precision electronics to have expected mass ranges beyond 1500Da with a power increase of less than twice that of its heritage implementations.
A model for meta-analysis of correlated binary outcomes: The case of split-body interventions.
Creators: name: Efthimiou, Orestis
name: Mavridis, Dimitris
name: Nikolakopoulou, Adriani
name: Rücker, Gerta
name: Trelle, Sven
name: Egger, Matthias
name: Salanti, Georgia
Publisher: name: SAGE Publications (UK and US)
Year: 2019
Subjects: 610 Medicine & health
360 Social problems & social services

description: In several areas of clinical research, it is common for trials to assign different sites of the participants' bodies to different interventions. For example, a randomized controlled trial comparing surgical techniques for correcting myopia may randomize each eye of a participant to a different operation. Under such bilateral ('split-body') interventions, the observations from each participant are correlated. It is challenging to account for these correlations at the meta-analysis level, especially when the outcome is rare. Here, we present a meta-analysis model based on the bivariate binomial distribution. Our model can synthesize studies on patients who received one intervention at one body site, patients who received two interventions at different sites or a mixture of these two groups. The model can analyse studies with zero events in one or both treatment arms and can handle the case of incomplete data reporting. We use simulations to assess the performance of our model and to compare it with the bivariate beta-binomial model. In the case of bilateral interventions, our model performed well and outperformed the bivariate beta-binomial model in all scenarios explored. We illustrate our methods using two previously published meta-analyses from the fields of orthopaedics and ophthalmology. We conclude that our model constitutes a useful new tool for the meta-analysis of binary outcomes in the presence of split-body interventions.
Characterization of CD34-deficient myofibroblastomas of the breast.
Creators: name: D'Alfonso, Timothy M
name: Subramaniyam, Shivakumar
name: Ginter, Paula S
name: Mosquera, Juan Miguel
name: Croyle, Jaclyn
name: Liu, Yi-Fang
name: Rubin, Mark Andrew
name: Shin, Sandra J
Publisher: name: Wiley
Year: 2018
Subjects: 500 Science
570 Life sciences; biology

description: Mammary myofibroblastoma is a benign spindle cell tumor that can show variable morphologic patterns and lines of differentiation. Diffuse and strong immunohistochemical expression of CD34 is a characteristic of myofibroblastoma and greatly aids in confirming a diagnosis. Myofibroblastoma has been shown to belong to a family of CD34-positive tumors with similar morphology that show a deletion of 13q14, which includes RB1 and FOXO1A genes. The purpose of this study was to better understand a subset of myofibroblastomas that is characteristically CD34-deficient by immunohistochemistry. Six myofibroblastomas were studied by immunohistochemistry and fluorescence in situ hybridization (FISH) for RB1. Patients included five women and one man, aged 41-85 years (median, 52.5). Tumor size ranged from 0.4 to 1.5 cm (mean, 0.95). Tumors showed spindle cell morphology in five cases and epithelioid features in one case. Two tumors showed complete lack of CD34 staining. The remaining showed weak focal or weak patchy CD34 staining. Dichotomous staining was seen in one case with CD34-positive spindle cell areas and CD34-negative myxoid areas. All six tumors showed ER expression, five of six showed desmin expression, and four of six showed bcl-2 positivity. Two of six (33.3%) tumors showed deletion of RB1 by FISH, including one that showed loss of Rb immunohistochemical staining. Myofibroblastomas uncommonly show absent/focal expression of CD34, a potential diagnostic pitfall, particularly in small samples. Characteristic staining with other immunohistochemical markers is seen which can aid in confirming the diagnosis. These tumors may harbor deletion of RB1, similar to CD34-positive myofibroblastomas, and this deletion may not correlate with loss of Rb by immunohistochemistry.
Implicit and explicit coordination mechanisms in youth football: temporal adaptations in team cognition and correlations to team performance
Creators: name: Blaser, Marc
Publisher: name: (:null)
Year: 2017
Subjects: 790 Sports, games & entertainment
150 Psychology

description: Members of a sport team ideally coordinate their actions in a way, that the desired outcome is reached as efficient as possible (Eccles and Tenenbaum, 2004, Journal of Sport & Exercise Psychology, 26, 542-560). However, flowing and efficient team action or plays without any coordination errors (e.g. bad pass) are differently coined in sport teams. Particularly in interactive team sports (e.g. football) which are characterised by highly complex, dynamic and uncertain situations, it is an advantage to share a common understanding concerning potential future actions. Otherwise, team members have to communicate (e.g. verbally) their thoughts and ideas what might be impossible due to time pressure and cognitive costs. The aim of the study was twofold: Firstly, we were interested how common understanding (implicit coordination mechanism) and verbal communication (explicit coordination mechanism) develop over time and practice and secondly, how the more appropriate implicit mechanism is related with team performance variables. With institutional ethics approval, 32 under 18 and under 21 youth football players (male, mean age: 17.8 ± 1.1) performed a football task in teams of two. The task consisted of passing and running elements that are common in football. After a training phase and before two testing phases, players evaluated their actions and the actions of their assigned teammates regarding action type, location, and timing. Out of these evaluations, an accordance index of common understanding was computed. Furthermore, verbal communication during the task was recorded and the whole task itself was videotaped. Team performance variables consisted of time to finish the task, fluidity (e.g. direct passing) and frequency of errors. Results show on one hand that common understanding significantly increased over time and practice (η2 = .56, P = .001). On the other hand, verbal communication was reduced, but not on a significant level (η2 = .13, P = .164). Furthermore, no significant correlations were found with quantitative team performance variables (e.g. time). Nonetheless, accordance index was significantly correlated with qualitative team performance measures (e.g. fluidity-error-coefficient; R2 = .261, P = .043). The preliminary results indicate a link between implicit and explicit coordination mechanisms: when common understanding increases, verbal communication decreases. Additionally, the correlation between common understanding and team performance is only apparent when qualitative aspects are considered. Further investigation is needed to uncover the oblique relations.
Additional file 2 of The potential role of the Asian bush mosquito Aedes japonicus as spillover vector for West Nile virus in the Netherlands
Creators: name: Linthout, Charlotte
name: Martins, Afonso Dimas
name: de Wit, Mariken
name: Delecroix, Clara
name: Abbo, Sandra R.
name: Pijlman, Gorben P.
name: Koenraadt, Constantianus J. M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 2: Table S2. Parameter estimates used for R0 calculation and simulation analysis. All rates are per day.
title: Alaska Salmon Research Task Force Report
Creators: name: Alaska Salmon Research Task Force
Publisher: name: NOAA National Marine Fisheries Service Alaska Fisheries Science Center
publisherIdentifier: https://ror.org/01h7fye62
publisherIdentifierScheme: ROR
Year: 2024

description: Under the Alaska Salmon Research Task Force Act, NOAA Fisheries, on behalf of the Secretary of Commerce, in collaboration with the State of Alaska, was required to convene a task force to review existing Pacific salmon research in Alaska and identify applied research needed to better understand the increased variability and declining salmon returns in some regions in order to support sustainable salmon runs in Alaska.
Ferite
Creators: name: Redazione, La
Publisher: name: Centro di Ateneo per le Biblioteche dell'Università di Napoli 'Federico II'
Year: 2017

description: L’idea centrale che attraversa questo numero è osservare da differenti prospettive e all’interno di scenari multipli il tema delle Ferite, fratture e lacerazioni identitarie iscritte nel soma e incarnate nella psiche. Punto di partenza è la scena corporea: dalle ferite deliberatamente inferte, al fenomeno del Self Cutting, tendenza frequente e diffusa tra adolescenti, principalmente ragazze e giovani donne, di tagliare e ferire la superficie della propria pelle.
description: La camera blu. Rivista di studi di genere, N° 14 (2016): Ferite
Explanation and Elaboration Document for the STROBE-Vet Statement: Strengthening the Reporting of Observational Studies in Epidemiology-Veterinary Extension.
Creators: name: O'Connor, A M
name: Sargeant, J M
name: Dohoo, I R
name: Erb, H N
name: Cevallos, M
name: Egger, M
name: Ersbøll, A K
name: Martin, S W
name: Nielsen, L R
name: Pearl, D L
name: Pfeiffer, D U
name: Sanchez, J
name: Torrence, M E
name: Vigre, H
name: Waldner, C
name: Ward, M P
Publisher: name: Wiley-Blackwell
Year: 2016
Subjects: 610 Medicine & health
360 Social problems & social services

description: The STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) statement was first published in 2007 and again in 2014. The purpose of the original STROBE was to provide guidance for authors, reviewers, and editors to improve the comprehensiveness of reporting; however, STROBE has a unique focus on observational studies. Although much of the guidance provided by the original STROBE document is directly applicable, it was deemed useful to map those statements to veterinary concepts, provide veterinary examples, and highlight unique aspects of reporting in veterinary observational studies. Here, we present the examples and explanations for the checklist items included in the STROBE-Vet statement. Thus, this is a companion document to the STROBE-Vet statement methods and process document (JVIM_14575 "Methods and Processes of Developing the Strengthening the Reporting of Observational Studies in Epidemiology-Veterinary (STROBE-Vet) Statement" undergoing proofing), which describes the checklist and how it was developed.
Feature
Creators: name: Jiang, Zhuoren
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 460506
subject: Graph, social and multimedia data
classificationCode: 441012
subject: Sociology of inequalities

description: sample_feature_distribution.csvsample_feature_distribution.csv is the time-evolving demographic feature distributions of aware population in the sampled 100,000 user setFormatThe first column is the time for different overall aware pencetageThe second column is the gender distributionThe third column is the age distributionThe fourth column is the occupation distributionThe fifth column is the education distributionThe sixth column is the marital status distributionThe seventh column is the parenthood status distribution
Teisėjų Sprendimų Priėmimas: Intuityvus Ir Racionalus Informacijos Apdorojimas
Creators: name: Maceina Tomas
name: Valickas Gintautas
Publisher: name: Zenodo
Year: 2018

description: Tyrime naudotos imitacinė ir tikslinė probleminės situacijos, susijusios su plėšimo nusikaltimais.
Review into Non-Educational Use of Mobile Devices in NSW Schools
Creators: name: Mannell, Kate
name: Fordyce, Robbie
Publisher: name: NSW Department of Education
Year: 2018

description: A response to the New South Wales Government's ban of non-educational use of phones in NSW Schools. While we were against the ban and also referenced heavily in the final report, the ban itself passed.

The actual submissions themselves were not made public from this inquiry.
Additional file 3 of The potential role of the Asian bush mosquito Aedes japonicus as spillover vector for West Nile virus in the Netherlands
Creators: name: Linthout, Charlotte
name: Martins, Afonso Dimas
name: de Wit, Mariken
name: Delecroix, Clara
name: Abbo, Sandra R.
name: Pijlman, Gorben P.
name: Koenraadt, Constantianus J. M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 3: Text S3. Estimation of biting rate and transmission probabilities.
Influence of Ammonium and Nitrate on Protein Content of Lemna minor L. during Photosynthesis
Einfluss von Ammonium und Nitrat auf den Proteingehalt von Lemna minor L. unter Photosynthesebedingungen
Creators: name: Feller, Urs
name: Dicht, M.
name: Erismann, Karl Hans
name: Kopp, A.
Publisher: name: Elsevier
Year: 1976
Subjects: 580 Plants (Botany)

description: Lemna minor L. on ammonium nutrient solution contains 25—30 % more total protein than on nitrate solution. In transition experiments from nitrate to ammonium the protein content increases immediately after the exchange of the nutrient solution and reaches the “steady state” value after about 40 hours. In the transition from ammonium to nitrate there is an initial lag period of about 10 hours, afterwards the protein content decreases rapidly and reaches the “steady state” value after 30—40 hours.
Impact of human papillomavirus on outcome in patients with oropharyngeal cancer treated with primary surgery.
Creators: name: Broglie, Martina A
name: Stoeckli, Sandro J
name: Sauter, Rafael
name: Pasche, Philippe
name: Reinhard, Antoine
name: De Leval, Laurence
name: Huber, Gerhard F
name: Pezier, Thomas F
name: Soltermann, Alex
name: Giger, Roland
name: Arnold, Andreas
name: Dettmer, Matthias
name: Arnoux, Andre
name: Müller, Martin
name: Spreitzer, Stefan
name: Lang, Florian
name: Lutchmaya, Mathieu
name: Stauffer, Edouard
name: Espeli, Vittoria
name: Martucci, Francesco
name: Bongiovanni, Massimo
name: Foerbs, Diana
name: Jochum, Wolfram
Publisher: name: J. Wiley
Year: 2017
Subjects: 610 Medicine & health

description: BACKGROUND Knowledge about prognostic factors in surgically treated patients with oropharyngeal squamous cell carcinoma (SCC) is limited. The purpose of this study was to identify influential factors on survival in a large cohort of patients with surgically treated oropharyngeal SCC. METHODS Retrospective analysis of survival estimates in patients with surgically treated oropharyngeal SCC using tumoral positivity for human papillomavirus (HPV) and risk-of-death categories according to a study from 2010 as stratification factors. RESULTS The 5-year overall survival (OS) and disease-specific survival (DSS) rates after surgery alone were higher in HPV-associated oropharyngeal SCC (OS 80% vs 62%; P = .01; DSS 92% vs 76%; P = .03). Patients in the low-risk category had higher survival rates (OS 91%; DSS 99%) than patients in the intermediate-risk group (OS 63%; DSS 83%), and high-risk group (OS 61%; DSS 75%). CONCLUSION Nonsmokers with HPV-positive oropharyngeal SCC have a better prognosis than smokers with HPV-positive oropharyngeal SCC and also than patients with HPV-negative tumors when treated by surgery alone.
title: Die Weltraumpolitik Chinas
Creators: name: Hauser, Manfred
Year: 2010

description: Die Arbeit beschreibt die Weltraumpolitik Chinas. Es wird den Fragen nachgegangen, welche Auswirkungen die von der VRC verfolgte Weltraumpolitik auf die Internationalen Beziehungen hat, wie weit China die Militarisierung des Orbits vorantrieb, und welche Ziele verfolgt China im Rahmen der Conference on Disarmament. Die Weltraumpolitik Chinas fokussiert auf mehrere Gesichtspunkte. Die Entwicklung und der Besitz bestimmter Weltraumtechnologie stellen für China Faktoren der äußeren Sicherheit, des internationalen wie innenpolitischen Prestiges und der Wirtschaft dar. Vor dem Hintergrund des Kalten Krieges entwickelt die VRC seine Weltraumfähigkeiten nahezu völlig Unabhängig. Zunächst sind die Weltraumaktivitäten auf den militärischen Bereich konzentriert. Im Laufe der Zeit ändern sich die politischen Intentionen. Die politische Führung in Peking wird sich des Nutzungspotentials des Alls immer mehr bewusst, sodass auch der zivilen Nutzung Bedeutung zugemessen wird. Der Orbit wird von China militärisch genützt, jedoch trachtet die VRC im Rahmen der CD eine „Weaponization“ des Kosmos zu verhindern. Offen bekennt es sich dazu, ein „Arms Race in Outer Space“ unter allen Umständen vermeiden zu wollen, denn nur dadurch ließe sich die friedliche Nutzung des Weltraums für alle Menschen gewährleisten.
description: The content of this diploma thesis deals with the space politics of China. The questions which are of interest are focused on the consequences of Chinas space politics concerning the international relations, how far is the militarization of space developed by China and what are the purposes and goals of China within the Conference on Disarmament. China faces a lot of considerations in the field of space. The development and the possession of certain kinds of space technology are inseparably connected to the factors of the external security, of the international and domestic prestige and the economic development. During the time of the Cold War, China succeeded independently in developing its space capacities. At the beginning the space activities have been concentrated on the military side, but during the time the political intentions changed. The political leadership in Beijing gets more and more aware of the importance and the possible benefits for the Chinese public. Nevertheless space is militarized by China, the “Red Dragon” aspires within the Conference on Disarmament in Geneva to prevent the “weaponization of space”. This gets obvious through Chinas efforts to create an international law binding treaty concerning the prohibition of placing weapons in Outer Space. China confesses officially to prevent an arms race in outer space by all means in order to keep the space peaceful.
The biomarker-based diagnosis of Alzheimer's disease. 2—lessons from oncology
Creators: name: Boccardi, Marina
name: Gallo, Valentina
name: Yasui, Yutaka
name: Vineis, Paolo
name: Padovani, Alessandro
name: Mosimann, Urs Peter
name: Giannakopoulos, Panteleimon
name: Gold, Gabriel
name: Dubois, Bruno
name: Jack, Clifford R.
name: Winblad, Bengt
name: Frisoni, Giovanni B.
name: Albanese, Emiliano
Publisher: name: Elsevier
Year: 2017
Subjects: 570 Life sciences; biology
610 Medicine & health

description: Biomarkers for the diagnosis of Alzheimer's disease (AD) are not yet validated for use in clinical settings. We aim to provide a methodological framework for their systematic validation, by reference to that developed for oncology biomarkers. As for this discipline, the steps for the systematic validation of AD biomarkers need to target analytical validity, clinical validity, and clinical utility. However, the premises are different from oncology: the nature of disease (neurodegeneration vs. cancer), the purpose (improve diagnosis in clinically affected vs. screening preclinical individuals), and the target population (mild cognitive impairment patients referring to memory clinics vs. general population) lead to important differences, influencing both the design of validation studies and the use of selected biomarkers. This framework is applied within a wider initiative to assess the current available evidence on the clinical validity of biomarkers for AD, for the final aim to identify gaps and research priorities, and to inform coordinated research efforts boosting AD biomarkers research.
Additional file 4 of The potential role of the Asian bush mosquito Aedes japonicus as spillover vector for West Nile virus in the Netherlands
Creators: name: Linthout, Charlotte
name: Martins, Afonso Dimas
name: de Wit, Mariken
name: Delecroix, Clara
name: Abbo, Sandra R.
name: Pijlman, Gorben P.
name: Koenraadt, Constantianus J. M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 4: Text S4 Derivation of the basic reproduction number.
An early innate response underlies severe influenza-induced exacerbations of asthma in a novel steroid-insensitive and anti-IL-5-responsive mouse model.
Creators: name: Adcock, I M
name: Sabogal Pineros, Y S
name: Sterk, P J
name: Dierdorp, B S
name: Lutter, R
name: Dekker, T
name: Logiantara, A
name: Villetti, G
name: Bal, S M
name: Ravanetti, L
name: Dijkhuis, A
name: Facchinetti, F
name: Rao, N L
name: Boon, L
Publisher: name: Wiley-Blackwell
Year: 2017

description: BACKGROUND Acute worsening of asthma symptoms (exacerbation) is predominantly triggered by respiratory viruses, with influenza causing the most severe exacerbations. The lack of an adequate animal model hampers mechanistic insight and the development of new therapeutics. AIM We developed and characterized a robust, consistent, and reproducible mouse model of severe exacerbation of chronic allergic asthma. METHODS Chronic allergic airway inflammation was induced following a house dust mite (HDM) sensitization protocol. HDM-sensitized mice and controls were infected with influenza virus A/X31 H3N2 and either or not treated with inhaled fluticasone propionate (FP), systemic corticosteroids (Pred), or anti-IL-5. Mice were killed at different time points after infection: Cellular accumulation and cytokines levels in the airways, PenH as a measure of airway hyper-responsiveness (AHR), and lung histology and viral replication were assessed. RESULTS Infection with low-dose A/X31 H3N2 led to prolonged deterioration of lung function, aggravated mucus production, peri-vascular, peri-bronchial, and allergic inflammation that was unresponsive to inhaled corticosteroids, but responsive to systemic corticosteroids. The exacerbation was preceded at 14 h after virus exposure by a marked innate, but no Th2 and Th1 response subsequently followed by enhanced numbers of eosinophils, neutrophils, dendritic, and T cells into the lung lumen, parenchyma, and draining lymph nodes in HDM-sensitized mice. Anti-IL-5 treatment attenuated eosinophils and prevented the X31-induced exacerbation. CONCLUSIONS Together, these findings indicate that an early innate response that involves eosinophils underlies the exacerbation. This model recapitulates all major features of severe asthma exacerbations and can serve to discern driving mechanisms and promote the development of novel therapeutics.
Additional file 5 of The potential role of the Asian bush mosquito Aedes japonicus as spillover vector for West Nile virus in the Netherlands
Creators: name: Linthout, Charlotte
name: Martins, Afonso Dimas
name: de Wit, Mariken
name: Delecroix, Clara
name: Abbo, Sandra R.
name: Pijlman, Gorben P.
name: Koenraadt, Constantianus J. M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 5: Text and Figure S5 Elasticity of the basic reproduction number.
The association between subclinical thyroid dysfunction and dementia: the Health, Aging and Body Composition (Health ABC) Study.
Creators: name: Aubert, Carole E
name: Bauer, Douglas C
name: Da Costa, Bruno R
name: Feller, Martin
name: Rieben, Carole
name: Simonsick, Eleanor M
name: Yaffe, Kristine
name: Rodondi, Nicolas
Publisher: name: Blackwell Scientific Publications
Year: 2017
Subjects: 610 Medicine & health
360 Social problems & social services

description: OBJECTIVE Data on the association between subclinical thyroid dysfunction and dementia are limited and conflicting. We aimed to determine whether subclinical thyroid dysfunction was associated with dementia and cognitive decline. DESIGN Population-based prospective cohort study. PATIENTS Adults aged 70-79 years with measured thyroid function, but no dementia at baseline, and Modified Mini-Mental State (3MS) at baseline and follow-up. MEASUREMENTS Primary outcome was incident adjudicated dementia, based on 3MS, hospital records, and dementia drugs. Secondary outcome was change in 3MS. Models were adjusted for age, sex, race, education, and baseline 3MS, and then further for cardiovascular risk factors. RESULTS Among 2558 adults, 85% were euthyroid (TSH 0.45-4.49mIU/L), 2% had subclinical hyperthyroidism with mildly decreased TSH (TSH 0.10- 0.44mIU/L), 1% subclinical hyperthyroidism with suppressed TSH (TSH<0.10mIU/L with normal free thyroxine [FT4]) and 12% subclinical hypothyroidism (TSH 4.50-19.99mIU/L with normal FT4). Over 9 years, 22% developed dementia. Compared to euthyroidism, risk of dementia was higher in participants with subclinical hyperthyroidisim with suppressed TSH (HR 2.38, 95%CI=1.13;5.04), while we found no significant association in those with mildly decreased TSH (HR 0.79, 95%CI=0.45;1.38) or with subclinical hypothyroidism (HR 0.91, 95%CI=0.70;1.19). Participants with subclinical hyperthyroidism with suppressed TSH had a larger decline in 3MS (-3.89, 95%CI=-7.62;-0.15). CONCLUSIONS Among older adults, subclinical hyperthyroidism with a TSH<0.10mIU/L was associated with a higher risk of dementia and a larger cognitive decline, while subclinical hyperthyroidism with mildly decreased TSH or subclinical hypothyroidism were not. This article is protected by copyright. All rights reserved.
The Role of Differentiation in EU Foreign, Security and Defence Policy Cooperation with Neighbouring Countries
Creators: name: Aydın-Düzgit, Senem
name: Bond, Ian
name: Scazzieri, Luigi
Publisher: name: Zenodo
Year: 2021
Subjects: European Union
EU Foreign Policy
Common Foreign and Security Policy (CFSP)
Common Security and Defence Policy (CSDP)

description: The EU extensively practices differentiation in its foreign, security and defence policy, both internally and externally towards its neighbours. Neighbouring countries are plugged into the EU’s Common Foreign and Security Policy and its Common Security and Defence Policy to different degrees, and also cooperate with groups of member states informally outside of the EU framework. The paper focuses on external differentiation in foreign and security policy, undertaking an in-depth assessment of the ways in which Albania, Georgia, Moldova, Montenegro, North Macedonia, Norway, Serbia, Turkey, Ukraine and the UK cooperate with the EU in foreign and security policy. The paper focuses on the effectiveness, sustainability and legitimacy of the EU’s external differentiation with its partners. Finally, it makes recommendations for how the EU and its partners might deepen foreign and security policy cooperation.