cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The collimated outflows of the planetary nebula Hu1-2: proper motion and radial velocity measurements
Creators: name: Miranda, L. F.
name: Blanco, M.
name: Guerrero, M. A.
name: Riera, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Hu\,1-2 is a planetary nebula that contains an isolated knot located northwestern of the main nebula, which could be related to a collimated outflow. We present a subsarcsecond H$α$+[N\,{\sc ii}] image and a high-resolution, long-slit spectrum of Hu\,1-2 that allow us to identify the southeastern counterpart of the northwestern knot and to establish their high velocity ($>$ 340 km\,s$^{-1}$), collimated bipolar outflow nature. The detection of the northwestern knot in POSS red plates allows us to carry out a proper motion analysis by combining three POSS red plates and two narrow-band H$α$+[N\,{\sc ii}] CCD images, with a time baseline of $\simeq$ 57 yr. A proper motion of 20 $\pm$ 6\,mas\,yr$^{-1}$ along position angle 312$^{\circ}$ $\pm$ 15$^{\circ}$, and a dynamical age of 1375$^{+590}$\llap{$_{-320}$}\,yr are obtained for the bipolar outflow. The measured proper motion and the spatio-kinematical properties of the bipolar outflow yield a lower limit of 2.7\,kpc for the distance to Hu\,1-2.
description: 6 pages, 4 figures; accepted for publication in MNRAS
Additional file 1 of Participatory prioritisation of interventions to improve primary school food environments in Gauteng, South Africa
Creators: name: Erzse, Agnes
name: Karim, Safura Abdool
name: Rwafa-Ponela, Teurai
name: Kruger, Petronell
name: Hofman, Karen
name: Foley, Louise
name: Oni, Tolu
name: Goldstein, Susan
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
classificationCode: 59999
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1. Detailed overview of how evidence-based interventions were adapted and matched with contextual drivers through the application of the Behaviour Change Wheel.
Exploring the Usefulness of Version Control Information for Program Comprehension
Creators: name: Al Baba, Mohamad Samer
Publisher: name: Graduate Studies
Year: 2012
Subjects: subject: Statistics
subject: FOS: Mathematics
subject: Artificial Intelligence
subject: Computer Science
subject: program comprehension
subject: concern comprehension
subject: version control systems
subject: software evolution
subject: commit ranking
subject: Data Mining
subject: Machine Learning
subject: classiﬁcation

description: Understanding a concern in source code can involve understanding its evolution. This work explores the usefulness of version control system information in supporting program understanding, by analyzing the evolution of twenty diﬀerent concerns from ﬁve open source software projects. Our analysis showed that 66.9% of commits are not helpful for understanding concerns and only 19.5% are very helpful. This result implies that it can be time consuming for programmers to ﬁnd relevant commits when reviewing a concern history and motivates the need for tool support for ranking commits associated with a concern. Hence, we have explored ranking commits based on a recommender system built on top of a classiﬁer whose input is some commit attributes. The accuracy of such ranking reached 75.5%. The analysis of mis-ranked commits demonstrated that improving on the current results will require a more sophisticated way for determining when a change is conceptually important or unimportant.
Proxy dynamic delegation in grid gateway
Creators: name: Calzolari, Federico
name: Licari, Daniele
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cryptography and Security (cs.CR)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences
subject: D.4.6

description: Nowadays one of the main obstacles the research comes up against is the difficulty in accessing the required computational resources. Grid is able to offer the user a wide set of resources, even if they are often too hard to exploit for non expert end user. Use simplification has today become a common practice in the access and utilization of Cloud, Grid, and data center resources. With the launch of L-GRID gateway, we introduced a new way to deal with Grid portals. L-GRID is an extremely light portal developed in order to access the EGI Grid infrastructure via Web, allowing users to submit their jobs from whatever Web browser in a few minutes, without any knowledge about the underlying Grid infrastructure.
description: 6 pages
รูปแบบการป้องกันโรคมือ เท้า ปาก ในศูนย์เด็กเล็กอำเภอเมืองในจังหวัดพัทลุงและจังหวัดตรัง
Creators: name: บงกช เชี่ยวชาญยนต
Publisher: name: กองนวัตกรรมและวิจัย กรมควบคุมโรค
Year: 2553
Subjects: รูปแบบเชิงรุก
การป้องกันโรคมือเท้าปาก
ศูนย์เด็กเล็ก

description: วารสารควบคุมโรค, 36, 2, 129-135
Gholamhosseini 2021.xlsx
Creators: name: Gholamhosseini, Ali
Publisher: name: figshare
Year: 2021
Subjects: subject: 60301 Animal Systematics and Taxonomy
subject: FOS: Biological sciences

description: An annotated list of bird species of Fars province (Southwestern Iran) including classification, scientific name, authority, common name, global distribution in zoogeographical regions, status of occurrence for Fars Province and conservation status. The asterisk indicates the species observed by the author.
การประเมินผลกระบวนการบริหารผลการปฏิบัติงานสำนักงานป้องกันควบคุมโรคที่ 10
Creators: name: สมศักดิ์ นาคกลิ่นกูล
Publisher: name: กองนวัตกรรมและวิจัย กรมควบคุมโรค
Year: 2553
Subjects: กระบวนการบริหารผลการปฏิบัติงาน
การมีส่วนร่วม

description: วารสารควบคุมโรค, 36, 3, 137-143
An Integrated Framework for Worker Planning and Supervision in Construction
Creators: name: Siriwardana, Chandana Sameera Attygala
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Engineering--Civil
subject: Construction Productivity
subject: Worker Planning
subject: Worker Grading
subject: Technical Skills Assessment
subject: Worker Performance Assessment

description: Construction is a highly labour-intensive industry; therefore, the planning of worker crews is vital to achieving quality, cost, schedule and productivity targets. However, current construction practices do not initiate worker planning during the early stages of construction, nor do they pay attention to the full life cycle of the project. These pitfalls lead to worker demotivation and performance and productivity losses. Comprehensive worker performance measurement evaluation criteria the Construction Worker Performance Index (CWPI) was developed. A pilot study was carried out to test the applicability and validity of the conceptual framework. After conducting an analytic hierarchy process (AHP) analysis, relative weights for the technical skills assessment framework of Borcherding et al. (2001) were refined; and, the technical skills assessment framework was expanded by adding more sub-attributes to make it suitable for assessing construction workers of Alberta, Canada. The CWPI worker performance measurement formula was finalized using two rounds of surveys based on Delphi survey principles. A worker grading scheme was developed that classifies workers beyond current conventional worker planning, which is based only on skill levels. A cohesion measurement framework was developed based the guidelines provided Carron et al. (1985) and Widmeyer et al. (1985). By integrating different aspects related to worker planning, an overall worker planning framework was created to cover the full life cycle of a construction project. The applicability of the developed framework was field-tested on a construction site in Alberta, Canada. The CWPI and cohesion values of 114 construction workers were measured and documented. Nine construction worker crews (further divided in to twenty sub-groups) were observed, and the structures of the worker crews were studied. Characteristics of high and low performing worker crews were identified, and relationships between factors were investigated. Management level perspective about the developed framework was obtained through a survey conducted among 28 building industry practitioners. Relationships among the factors of the framework were investigated using a correlation analysis. A regression analysis was conducted to determine the causality between input factors and the cohesion level of worker crews. Finally, the limitations of the research were identified, and recommendations for future research were provided.
Spectral and spatial observations of microwave spikes and zebra structure in the short radio burst of May 29, 2003
Creators: name: Chernov, G. P.
name: Sych, R. A.
name: Meshalkina, N. S.
name: Yan, Y.
name: Tan, C.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The unusual radio burst of May 29, 2003 connected with the M1.5 flare in AR 10368 has been analyzed. It was observed by the Solar Broadband Radio Spectrometer (SBRS/Huairou station, Beijing) in the 5.2-7.6 GHz range. It proved to be only the third case of a neat zebra structure appearing among all observations at such high frequencies. Despite the short duration of the burst (25 s), it provided a wealth of data for studying the superfine structure with millisecond resolution (5 ms). We localize the site of emission sources in the flare region, estimate plasma parameters in the generation sites, and suggest applicable mechanisms for interpretating spikes and zebra-structure generation. Positions of radio bursts were obtained by the Siberian Solar Radio Telescope (SSRT) (5.7 GHz) and Nobeyama radioheliograph (NoRH) (17 GHz). The sources in intensity gravitated to tops of short loops at 17 GHz, and to long loops at 5.7 GHz. Short pulses at 17 GHz (with a temporal resolution of 100 ms) are registered in the R-polarized source over the N-magnetic polarity (extraordinary mode). Dynamic spectra show that all the emission comprised millisecond pulses (spikes) of 5-10 ms duration in the instantaneous band of 70 to 100 MHz, forming the superfine structure of different bursts, essentially in the form of fast or slow-drift fibers and various zebra-structure stripes. Five scales of zebra structures have been singled out. As the main mechanism for generating spikes (as the initial emission) we suggest the coalescence of plasma waves with whistlers in the pulse regime of interaction between whistlers and ion-sound waves. In this case one can explain the appearance of fibers and sporadic zebra-structure stripes exhibiting the frequency splitting.
description: 11 pages, 5 figures, in press; A&A 2012
ปัจจัยที่มีผลต่อพฤติกรรมการป้องกันโรคหลอดเลือดหัวใจของบุคลากรกรมควบคุมโรค
Creators: name: ศรีเพ็ญ สวัสดิมงคล
Publisher: name: กองนวัตกรรมและวิจัย กรมควบคุมโรค
Year: 2553
Subjects: โรคหลอดเลือดหัวใจ
ปัจจัยที่มีผล
พฤติกรรมการป้องกัน

description: วารสารควบคุมโรค, 36, 3, 144-153
Mechanisms of Synapse Formation and Synaptic Plasticity
Creators: name: Luk, Collin Chill-Fone
Publisher: name: Graduate Studies
Year: 2015
Subjects: subject: Neuroscience
subject: Synaptogenesis
subject: Trophic factors
subject: Growth cones
subject: Short-term potentiation

description: Synapses are the fundamental building blocks of the nervous system. Following target cell contact, they are formed through a process that requires the precise orchestration of both pre- and postsynaptic differentiation of synaptic machinery. However, the precise time course of synaptogenesis, and the role of extrinsic factors in synapse formation remains unclear. To examine the time course of synaptogenesis, I developed a novel “growth ball” model to study synapse at the level of isolated growth cones. Specifically, I found that functional synapses can reform in isolated growth cones within minutes of contact with their synaptic partner. However, in the absence of the cell body, these synapses cannot be maintained. To further investigate the importance of the cell body, I demonstrate that extrinsic trophic factors can “prime” postsynaptic neurons for synapse formation through the functional expression of excitatory acetylcholine receptors via activity dependent mechanisms. Specifically, trophic factor induced activity follows a specific pattern of progression, which I termed an activity “signature”, that is necessary for proper expression of excitatory acetylcholine receptors. Finally, I demonstrate and characterize a novel form of use-dependent short-term potentiation that is observed in the visceral dorsal 1/left pedal dorsal 1 synapse. This synaptic plasticity is induced rapidly by a short presynaptic tetanic pulse and remains potentiated until a subsequent action potential is triggered in a use- rather than time-dependent manner. I show that the molecular switch underlying this form of potentiation is calcium/calmodulin kinase II (CaMKII). Taken together, these studies demonstrate both intrinsic and extrinsic mechanisms of synapse formation and identify a novel role for CaMKII in a use-dependent form of synaptic plasticity.
Neural network dynamics during the generation and reinstatement of mnemonic representations
Creators: name: Arnold, Aiden
Publisher: name: Graduate Studies
Year: 2017
Subjects: subject: Neuroscience
subject: Psychology--Cognitive
subject: memory
subject: Hippocampus
subject: Navigation
subject: prospection
subject: mental simulation
subject: Graph Theory

description: The capacity to generate, reinstate, and mentally simulate mnemonic representations is a fundamental aspect of the human mind. It allows us to internally experience other places and moments of time, abstracting away from the present moment into past experiences or hypothetical future states of the world. Theoretical models posit that this capacity is afforded by a neural network distributed across the brain that codes features from our environment and experiences into neural representations that can be reinstated or flexibly combined in a goal oriented manner. Central to this network is the hippocampus, a region of the medial temporal lobes that putatively indexes both the spatial composition of a mental scene and the pattern of hippocampal-cortical interactions that represent feature details. Despite decades of research on hippocampal function during memory processes, our understanding of how this neural network operates dynamically remains limited. This thesis aim to assist in resolving this by investigating patterns of network reconfiguration that occur as a mnemonic representation of a virtual city is generated and reinstated to guide mental simulations of movement through the city. Chapter 2 provides evidence for a general encoding mechanism where the brain transitions from a state of information integration to localized processing based on encoding demands. These results are extended by showing that the hippocampus demonstrates flexibility in how it interacts with other brain regions to actively reinstate and bind features into a holistic representation that is used for mentally simulating movement. Chapter 3 investigates regional effects associated with the task as a validity check. Chapter 4 uses network reconfiguration processes to show that the default mode network, a putative task-negative system, also demonstrates flexibility by altering the functional interactions between its components and regions of the mental simulation network to facilitate feature integration during mnemonic reinstatement. Collectively, these results provide a schematic for extending existing theoretical models on memory function into a dynamic perspective based on the adaptability of neural networks and the flexibility of network components to alter patterns of functional interactions across the brain to process information in a contextual, goal oriented manner.
Evaluation of the outcome and adverse event of intravenous Vitamin C in the treatment of septic shock or acute respiratory distress syndrome (ARDS) among patients admitted to the intensive care unit (ICU) of a tertiary hospital in Malaysia
Creators: name: OH Hoey Lin
name: Calvin, WONG Ke Wen
name: Shuen, THONG Kah
name: Weng, FOONG Kit
Publisher: name: Zenodo
Year: 2021
Subjects: acute respiratory distress syndrome
ARDS
intravenous vitamin C
clinical outcome
all-cause mortality rate
observational study

description: Introduction:
 Numerous studies have suggested that Vitamin C may enhance sepsis recovery and improve clinical outcome in acute respiratory distress syndrome (ARDS) through its effect in attenuating organ failure and improving the microcirculation and hemodynamic parameters. Methodology:
 A retrospective observational study was conducted between 2018 and 2020 among patients admitted to the intensive care unit and received intravenous vitamin C for septic shock or ARDS (N=35). Primary outcome was the vasopressor and ventilator-free-days at day 28 of treatment. Results:
 The vasopressor and ventilator-free-day at day 28 of intravenous vitamin C was 9 days (IQR 0,25) and 12 days (IQR 0,22) respectively; which was shorter compared to the VICTAS study (25 days). Resolution of shock was observed in 66% of the patients (n=23) within 46 hours and this finding was consistent with the results of HYVCTTSSS study. The vasopressor requirement was reduced for 36% within 24 hours of treatment (from 0.63mcg/kg/min to 0.4mcg/kg/min of Norepinehrine equivalent doses). However, the 28-day all-cause mortality rate was higher compared to other studies (55% vs 20-35%). This may be due to the high SOFA score (14 and above) among these patients prior to treatment and a delay in treatment from the onset of shock (> 24 hours as recommended in 10 out of the 19 deceased patients). Conclusions:
 Although the 28-day all-cause mortality rate was higher in our patients, rapid resolution of shock was observed among those who responded to the intravenous vitamin C treatment.

description: This poster was submitted to the 14th National Conference for Clinical Research (NCCR) in August 18-20, 2021. https://nccrconference.com.my/
Code-division multiplexing for x-ray microcalorimeters
Creators: name: Stiehl, G. M.
name: Doriese, W. B.
name: Fowler, J. W.
name: Hilton, G. C.
name: Irwin, K. D.
name: Reintsema, C. D.
name: Schmidt, D. R.
name: Swetz, D. S.
name: Ullom, J. N.
name: Vale., L. R.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We demonstrate the code-division multiplexed (CDM) readout of eight transition-edge sensor microcalorimeters. The energy resolution is 3.0 eV (full width at half-maximum) or better at 5.9 keV, with a best resolution of 2.3 eV and a mean of 2.6 eV over the seven modulated detectors. The flux-summing CDM system is described and compared with similar time-division multiplexed (TDM) readout. We show that the sqrt(Npixels) multiplexing disadvantage associated with TDM is not present in CDM. This demonstration establishes CDM as both a simple route to higher performance in existing TDM microcalorimetric experiments and a long-term approach to reaching higher multiplexing factors.
description: To be published in Applied Physics Letters
The burden and costs of septic shock in Intensive Care Unit in a tertiary hospital, Malaysia
Creators: name: NG Chin Hui
name: OH Hoey Lin
name: Calvin, WONG Ke Wen
name: Shuen, THONG Kah
name: Weng, FOONG Kit
Publisher: name: Zenodo
Year: 2021
Subjects: septic shock
burden
cost
Intensive Care
intravenous ascorbic acid

description: Introduction:
 The burden of septic shock management is ascertained. This study aimed to explore the burden of septic shock management in the Intensive Care Unit (ICU) in a tertiary hospital and to evaluate the effect of intravenous ascorbic acid in this population.

 Methodology:
 A retrospective observational study was conducted between 2018 and 2020 on the cost of surviving and non-surviving sepsis patients from a paymaster perspective. Medical records were abstracted to identify events and resources consumed in ICU retrospectively. The cost accrued was received from the price listed by the Attorney General's Chambers of Malaysia for foreigner and private pathology lab. The price list of types and quantities of healthcare components utilized during the patient's stay were taken into consideration. Results:
 An average cost of treatment in ICU for sepsis patients was RM14,833.50 (CI: RM10,560.94, 95%CI). From the 35 sepsis shock patients, 71.43% passed on and 28.57% survived and were discharged from ICU. The mean hospital costs incurred per surviving patient was RM 5,813.07 and the average stay in ICU was 6.90 days. The mean hospital cost incurred per death in ICU was RM18,441.67 with an average stay of 23 days. Only the number of total ICU stay has a strong relationship (r:-0.99) with the management cost. The proportion of the cost of intravenous ascorbic acid was 2.84% (CI: 0.65%,95%CI) from the total management cost. The majority of the expenses accrued was from laboratory tests which was 52.98% (CI:1.03,95%CI). Conclusions:
 This study provided insight with the efficacy of intravenous ascorbic acid and the burden of sepsis shock management in ICU. Disclaimer: Abstract text might vary slightly from what is displayed in the e-poster.
description: This poster was submitted to the 14th National Conference for Clinical Research (NCCR) in August 18-20, 2021. https://nccrconference.com.my/
Autonomous models solvable through the full interval method
Creators: name: Khorrami, Mohammad
name: Aghamohammadi, Amir
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The most general exclusion single species one dimensional reaction-diffusion models with nearest-neighbor interactions which are both autonomous and can be solved exactly through full interval method are introduced. Using a generating function method, the general solution for, $F_n$, the probability that $n$ consecutive sites be full, is obtained. Some other correlation functions of number operators at nonadjacent sites are also explicitly obtained. It is shown that for a special choice of initial conditions some correlation functions of number operators called full intervals remain uncorrelated.
Two-point theory for the differential self-interrogation Feynman-alpha method
Creators: name: Anderson, Johan
name: Chernikova, Dina
name: Pazsit, Imre
name: Pal, Lenard
name: Pozzi, Sara A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mathematical Physics (math-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: A Feynman-alpha formula has been derived in a two region domain pertaining the stochastic differential self-interrogation (DDSI) method and the differential die-away method (DDAA). Monte Carlo simulations have been used to assess the applicability of the variance to mean through determination of the physical reaction intensities of the physical processes in the two domains. More specifically, the branching processes of the neutrons in the two regions are described by the Chapman - Kolmogorov equation, including all reaction intensities for the various processes, that is used to derive a variance to mean relation for the process. The applicability of the Feynman-alpha or variance to mean formulae are assessed in DDSI and DDAA of spent fuel configurations.
description: 15 pages, 5 figures. Submitted to EPJ Plus
НОРМАТИВНО-ПРАВОВОЕ РЕГУЛИРОВАНИЕ РАЗВИТИЯ ПРЕДПРИНИМАТЕЛЬСТВА В СФЕРЕ ТУРИСТИЧЕСКИХ УСЛУГ
Creators: name: научный руководитель, и.о. проф. - Каримова А.М.
name: соискатель, СамИЭС - Максудов О.Ш.
Publisher: name: Zenodo
Year: 2025

description: Нормативно-правовое регулирование субъектов предпринимательства сферы туристических услуг, является одним из значительных регуляторов развития данной отрасли. Проведенные исследования свидетельствуют о том, что сложившаяся во всем мире эпидемиологическая ситуация связанная с коронавирусной пандемии COVID-19 оказала значительное влияние на туризм, что в свою очередь проявила отрицательное влияние на предпринимательскую деятельность в данной сфере. в статье рассматривается перечень нормативных актов, принятых на смягчения влияния эпидемиологической ситуацией COVID-19,  а также нормативно-правовые акты регламентирующие деятельность и развития предпринимательства сферы туристических услуг. Сделаны выводы и даны заключения.

Ключевые слова: банк, туризм, предпринимательство, кредит, финансовые ресурсы, COVID-19, бизнес, налог, конкуренция, инновационные идеи, компания, вклад, собственные средства, заемные средства, стабильность.
Mode of action of dieldrin-induced liver tumors: application to human risk assessment
Creators: name: Klaunig, James E.
name: Cohen, Samuel M.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Dieldrin is an organochlorine insecticide that was widely used until 1970 when its use was banned because of its liver carcinogenicity in mice. Several long-term rodent bioassays have reported dieldrin to induce liver tumors in in several strains of mice, but not in rats. This article reviews the available information on dieldrin liver effects and performs an analysis of mode of action (MOA) and human relevance of these liver findings. Scientific evidence strongly supports a MOA based on CAR activation, leading to alterations in gene expression, which result in increased hepatocellular proliferation, clonal expansion leading to altered hepatic foci, and ultimately the formation of hepatocellular adenomas and carcinomas. Associative events include increased liver weight, centrilobular hypertrophy, increased expression of Cyp2b10 and its resulting increased enzymatic activity. Other associative events include alterations of intercellular gap junction communication and oxidative stress. Alternative MOAs are evaluated and shown not to be related to dieldrin administration. Weight of evidence shows that dieldrin is not DNA reactive, it is not mutagenic, and it is not genotoxic in general. Furthermore, activation of other pertinent nuclear receptors, including PXR, PPARα, AhR, and estrogen are not related to dieldrin-induced liver tumors nor is there liver cytotoxicity. In previous studies, rats, dogs, and non-human primates did not show increased cell proliferation or production of pre-neoplastic or neoplastic lesions following dieldrin treatment. Thus, the evidence strongly indicates that dieldrin-induced mouse liver tumors are due to CAR activation and are specific to the mouse, which are qualitatively not relevant to human hepatocarcinogenesis. Thus, there is no carcinogenic risk to humans. This conclusion is also supported by a lack of positive epidemiologic findings for evidence of liver carcinogenicity. Based on current understanding of the mode of action of dieldrin-induced liver tumors in mice, the appropriate conclusion is that dieldrin is a mouse specific liver carcinogen and it does not pose a cancer risk to humans.
El Infinito y el Continuo en el sistema numérico
Creators: name: Dib, Eduardo Daniel
Publisher: name: Zenodo
Year: 2019
Subjects: Infinite
Continuum
Cantor
Dedekind
Russell
Turing
Church

description: This monography provides an overview of the conceptual developments that lead from the traditional views of infinite (and their paradoxes) to the contemporary view in which those old paradoxes are solved but new problems arise. Also a particular insight in the problem of continuity is given, followed by applications in theory of computability.
description: UNDERGRADUATE THESIS ("Tesis de Licenciatura" in Spanish), presented and defended in 1995
T-type Calcium Channels in Arterial Smooth Muscle: Activity, Regulation and Function
Creators: name: Harraz, Osama Fathalla
Publisher: name: Graduate Studies
Year: 2015
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Biophysics
subject: Pharmacology
subject: Calcium channels
subject: Potassium channels
subject: Vascular Smooth Muscle
subject: Cerebral arteries
subject: Myogenic response
subject: Cav3.2
subject: Cav1.2
subject: Cav3.1
subject: BKCa

description: Voltage-gated Ca2+ channels (CaV) are key regulators of excitation-contraction coupling in arterial smooth muscle. Despite evidence of T-type CaV channels in rodent smooth muscle, little is known of their regulation and function. This thesis sought to delineate T-type Ca2+ channels, ascertain if they are regulatory targets of vasoactive signaling pathways, and to reveal their function in arterial smooth muscle. Experiments progressed from cells to whole animals, and employed an integrative range of techniques such as electrophysiology, pressurized myography, intravascular catheterization, polymerase chain reaction, western blotting and computational modeling. Using patch clamp electrophysiology and defined pharmacology, T-type currents were successfully separated from L-type, and further divided into components mediated by specific subtypes (i.e. CaV3.1 and CaV3.2). In rat cerebral arteries, T-type channel activity was shown to be a regulatory target of vasodilatory kinases. In particular, β-adrenergic receptors and downstream activation of protein kinase A selectively inhibited CaV3.2 currents. Nitric oxide additionally suppressed CaV3 channels through protein kinase G signaling. Subsequent work on rat and mouse arteries revealed an unanticipated function for CaV3.2 in arterial tone development. In particular, we identified a novel feedback response mediated by CaV3.2, whereby it triggered ryanodine receptors to release Ca2+ sparks that consequently activate the large conductance Ca2+-activated K+ channel to hyperpolarize and relax arteries. While the majority of the experimental work was conducted in animals, access to human brain tissues provided the opportunity to translate our foundational observations. Indeed, human findings revealed for the first time the presence of three distinct CaV subtypes in cerebral arterial smooth muscle and that each subtype uniquely orchestrates arterial tone development and blood flow. In conclusion, this thesis revises our knowledge on Ca2+ handling in arterial smooth muscle by describing a novel paradigm in which T-type channels either facilitate or counteract arterial tone development.
Programa online basado en el protocolo unificado para la prevención de problemas emocionales durante tratamientos de reproducción asistida.
Creators: name: Martínez-Borba, Verónica
name: Osma, Jorge
name: Crespo-Delgado, Elena
name: Andru-Pejo, Laura
name: Monferrer-Serrano, Alba
Publisher: name: Psicosomàtica y Psiquiatría
Year: 2022

description: Psicosomàtica y Psiquiatría, Núm. 21 (2022): abril-mayo-junio
QU Carinae: Supernova Ia in the making?
Creators: name: Kafka, Stella
name: Honeycutt, Kent
name: Williams, Bob
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Variable NaI absorption lines have been reported in a number of type Ia supernovae (SNeIa). The presence of this circumstellar material suggests that cataclysmic variables (CVs) with a giant donor star may be the progenitors of these SNeIa (Patat et al. 2007). We present echelle spectra of the CV QU Carinae which strengthen the connection between CVs of the V Sge class, the Accretion Wind Evolution scenario, variable wind features, variable NaI absorption, and SNIa. This thread not only provides insight into the spectral peculiarities of QU Car, but also links SNeIa as a class with their parent systems.
description: Accepted for publication to MNRAS. 23 pages (4 figures, 3 tables)
Evaluation of rat and rabbit embryofetal development studies with pharmaceuticals: the added value of a second species
Creators: name: Roos, Puck
name: Anggasta, Caroline
name: Piersma, Aldert H.
name: van Meer, Peter J.K.
name: Theunissen, Peter T.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Pharmacology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: Embryofetal development (EFD) studies are performed to characterize risk of drugs in pregnant women and on embryofetal development. In line with the ICH S5(R3) guideline, these studies are generally conducted in one rodent and one non-rodent species, commonly rats and rabbits. However, the added value of conducting EFD studies in two species to risk assessment is debatable. In this study, rat and rabbit EFD studies were evaluated to analyze the added value of a second species. Information on rat and rabbit EFD studies conducted for human pharmaceuticals submitted for marketing authorization to the European Medicines Agency between 2004 and 2022 was collected from the database of the Dutch Medicines Evaluation Board, along with EFD studies conducted for known human teratogens. In total, 369 compounds were included in the database. For 55.6% of the compounds similar effects were observed in rat and rabbit EFD studies. Discordance was observed for 44.6% of compounds. Discordance could often be explained based on occurrence of maternal toxicity or the compound’s mechanism of action. For other compounds, discordance was considered of limited clinical relevance due to high exposure margins or less concerning EFD toxicity. For 6.2%, discordance could not be explained and was considered clinically relevant. Furthermore, for specific therapeutic classes, concordance between rat and rabbit could vary. In conclusion, in many cases the added value of conducting EFD studies in two species is limited. These data could help identify scenarios in which (additional) EFD studies could be waived or create a weight-of-evidence model to determine the need for (additional) EFD studies.
Additional file 1 of A scoping review of statistical methods in studies of biomarker-related treatment heterogeneity for breast cancer
Creators: name: Sollfrank, L
name: Linn, SC
name: Hauptmann, M
name: Jóźwiak, K
Publisher: name: figshare
Year: 2023
Subjects: subject: Statistics
subject: FOS: Mathematics

description: Supplementary Material 1
Repetition with revision : Suzan-Lori Parks' 365 days/365 plays and the new theatre festival
Creators: name: Leadley, Allison
Publisher: name: University of British Columbia
Year: 2010

description: In November of 2002, Pulitzer-prize winning playwright Suzan-Lori Parks began her largest writing project to date: writing a play a day for a full year. Four years later, with the assistance of producer Bonnie Metzgar, Parks’ plays were divided into individual weeklong cycles and distributed between nearly eight hundred theatre artists and companies across North America. The international panoptic premiere of Parks’ 365 Days/365 Plays was the largest theatrical premiere to date and nearly two years after the cycle has come to a close, its expansive temporal and geographical scope remains unparalleled. Like many of her other works, Parks’ 365 creates opportunity for discourse and with the cycle’s completion, theatre scholars have written extensive literary and dramaturgical analyses of the project. Still, scholars continue to contest exactly what constitutes Parks’ unique project and identify its implications for American stages. In reviewing the relevant literature surrounding the project, the term “festival” is continually applied to 365 by both artists (including the playwright) and scholars alike. In working to define 365 however, these respective scholars and practitioners have evoked a complex theatrical framework with its own criteria and inferences. Largely missing from their respective analysis of the project however is a detailed performative and theoretical evaluation of the festival itself. Thus, lingering questions regarding this specific performative framework and whether Parks’ project can and does indeed function within its parameters remain. Are scholars correct in their assumption of 365 as a festival? What are the respective limitations in evoking this term (if any) to describe Parks’ project? Through a detailed literary analysis of the scholarship surrounding Parks’ project I aim to interrogate both the performative and theoretical significance of this term as it is applied to 365 Days/365 Plays to determine not only whether we can rightly refer to Parks’ project as such, but to also recognize the efficacy of the term as scholars move forward in their analysis of the cycle.
HappyFeet: Embodiments for Joint Remote Dancing
Creators: name: Alizadeh Talarposhti, Hesam
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Dance
subject: Remote Exercise
subject: Visual Embodiment
subject: Visual Interaction

description: Prior research has demonstrated that exercise is more fun and engaging when we exercise with others. Yet for many people, it is challenging to exercise with partners that are co-present due to several reasons (e.g. lack of access to a partner). In this thesis, I explore the challenge of designing an exercise system that effectively embodies a remote participant. The result of my exploration is HappyFeet, a dancing system that supports the dancing experience for remotely located partners. HappyFeet uses 3D representations of dancers’ feet in a shared virtual dance space to emphasize timing and placement of feet. My work demonstrates that the feet embodiment provides the dancers with a better understanding of dance moves, helps them to synchronize timing of their dance steps, and provides them with a dance space in which they can freely create dance moves with their partners.
การเปรียบเทียบปัจจัยเสี่ยงระหว่างผู้ป่วยเบาหวานมีแผลที่เท้ากับผู้ป่วยเบาหวานไม่มีแผลที่เท้าในโรงพยาบาลเดิมบางนางบวช
Creators: name: ประภาส จิบสมานบุญ
Publisher: name: กองนวัตกรรมและวิจัย กรมควบคุมโรค
Year: 2553
Subjects: โรคเบาหวาน
แผลที่เท้า
โรงพยาบาลเดิมบางนางบวช

description: วารสารควบคุมโรค, 36, 3, 154-163
Survey of digital access among cardiology clinic patients in Queen Elizabeth Hospital II
Creators: name: SAHARUDIN Sahrin
name: JAM Emelyne Bani
name: LIEW Houng Bang
Publisher: name: Zenodo
Year: 2021
Subjects: digital access
cardiology clinic
telehealth
survey

description: Introduction :
 Virtual clinic is where health care professional giving consultations, advice and treatment planning. In the midst of COVID-19 outbreak, this is one potential area should be look into. Our study aim to determine the digital access among cardiology patient in Hospital Queen Elizabeth II. Methodology :
 This is a cross-sectional study conducted involving outpatients in Cardiology Clinic in Hospital Queen Elizabeth II from 1st to 30th June 2020 retrospectively. Secondary data collected from cardiology clinic were obtained and inclusion criteria included patients 18 years of age and above. Results :
 Mean age is 54 years old (SD 15.45). Out of 693 respondents, 59.7% (n=414) is male. At least 70% of the respondents went to secondary school. More than half came from west coast of Sabah (67.5%). About 84.4% (n=588) of respondent owns at least a mobile phone. 82% (n=482) of them use it to access the internet. Whatsapp usage by patients and caretaker is at 75% (n=525). Discussion: At least two over third of the respondent have a smartphone with an internet access capability. Whatsapp is most preferred platform among the patients. Thus, from these finding, virtual clinic is feasable to be done in this pandemic era and intergrate it into existing standard of carepath. Conclusion:
 Pilot virtual clinic need to be demonstrated to improve the healthcare system. More research on telehealth should be done to move forward and bridge the gap between patients and health care personnel. Disclaimer: Abstract text might vary slightly from what is displayed in the e-poster.
description: This poster was submitted to the 14th National Conference for Clinical Research (NCCR) in August 18-20, 2021. https://nccrconference.com.my/
Additional file 2 of A scoping review of statistical methods in studies of biomarker-related treatment heterogeneity for breast cancer
Creators: name: Sollfrank, L
name: Linn, SC
name: Hauptmann, M
name: Jóźwiak, K
Publisher: name: figshare
Year: 2023
Subjects: subject: Statistics
subject: FOS: Mathematics

description: Supplementary Material 2
Trimaximal neutrino mixing from vacuum alignment in A4 and S4 models
Creators: name: King, Stephen F.
name: Luhn, Christoph
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Recent T2K results indicate a sizeable reactor angle theta_13 which would rule out exact tri-bimaximal lepton mixing. We study the vacuum alignment of the Altarelli-Feruglio A4 family symmetry model including additional flavons in the 1' and 1" representations and show that it leads to trimaximal mixing in which the second column of the lepton mixing matrix consists of the column vector (1,1,1)^T/sqrt{3}, with a potentially large reactor angle. In order to limit the reactor angle and control the higher order corrections, we propose a renormalisable S4 model in which the 1' and 1" flavons of A4 are unified into a doublet of S4 which is spontaneously broken to A4 by a flavon which enters the neutrino sector at higher order. We study the vacuum alignment in the S4 model and show that it predicts accurate trimaximal mixing with approximate tri-bimaximal mixing, leading to a new mixing sum rule testable in future neutrino experiments. Both A4 and S4 models preserve form dominance and hence predict zero leptogenesis, up to renormalisation group corrections.
description: 24 pages, 2 figures, version to be published in JHEP
Patient Satisfaction With An Interprofessional Approach to Wound Care in Qatar
Creators: name: AlQahtani, Shaikha
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Nursing
subject: FOS: Health sciences
subject: Interprofessional Collaboration
subject: interprofessional education
subject: Patient satisfaction

description: In general, patient satisfaction within health care services is an important indicator of the patients' confidence in the health care system and a significant indicator of the quality of health care services delivered. In this study, I have measured the level of patient satisfaction wound care service delivery at the Hamad General Hospital Outpatient Wound Clinic in Doha, Qatar. To complete this research I conducted a cross sectional study design to survey patients who received wound care services from a interprofessional team from January 2015 to February 2016. Through this data collection method I solicited these patient’s opinions on the service they received through the interprofessional approach. A total of 111 respondents completed a Client Satisfaction questionnaire (Attkisson, 1983), modified to include questions on socio-demographic characteristics. Data collection was completed from December 2015 to February 2016. Overall, results from this study showed that patients were generally satisfied with wound care services delivered by a interprofessional team, as assessed by the client satisfaction questionnaire. The results revealedfavorable ratings of satisfaction ranging from 67.9% to 90.1%. These results indicate that the approach by which services are provided through an interprofessional approach which brings together professionals from various departments, has a positive impact on the patients’ satisfaction with care received.
Measurement of the Rapidity and Transverse Momentum Distributions of Z Bosons in pp Collisions at sqrt(s)=7 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Measurements of the normalized rapidity (y) and transverse momentum (qT) distributions of Drell-Yan muon and electron pairs in the Z-boson mass region (60
The Effects of Dispersal and Pollination on Plantaginaceae Diversification
Creators: name: Ogutcen, Ezgi
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Botany
subject: Ecology
subject: FOS: Biological sciences
subject: Plant Evolution
subject: Diversification
subject: Speciation
subject: Dispersal
subject: Pollination
subject: Biogeography
subject: Plantaginaceae

description: The rich diversity of flowering plants can be explained by a variety of mechanisms, including geographical distribution, range expansion, and floral variance, which correlates with different biotic pollination forms. Plantaginaceae is an ideal model to examine these mechanisms providing the angiosperm diversity, as the family has diverse distribution patterns both in the Old World and the New World, and the family has representatives of many different pollination syndromes. Using molecular phylogenetics, ancestral reconstructions, and phylogenetic modeling and hypothesis testing, this study aimed to investigate the factors affecting the macroevolution of the angiosperm family Plantaginaceae. With 683 species from 72 genera, and a total of 6996 characters from 5 different molecular markers, the phylogenetic reconstruction revealed that Plantaginaceae have 12 strongly supported monophyletic tribes. The family was inferred to have a New World origin, and experienced several long-distance dispersal events between the Old World and the New World. In some cases, these long-distance dispersals were linked to chromosome number changes in the family. Sympatric speciation was shown to be a significant diversification mode in the family, which had some heterogeneity in terms of speciation rates among the tribes. These diversification patterns were not correlated with geographic distribution, as diversification rates in the Old World and the New World were similar. However, long-distance dispersals are found to be the main drivers of speciation within the family. Lastly, pollination was shown to have no effect on diversification in the tribe Antirrhineae In summary, this study investigated the diversification patterns within the diverse angiosperm family Plantaginaceae. Since its origin in the New World approximately 48.81 mya, the family has experienced several long-distance dispersal events between the Old World and the New World. Along with the changes in chromosome numbers, long-distance dispersal was found to be a strong contributor to the diversity in the family.
MPEC 2023-W147 : TWO NEW TNOS
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: TWO NEW TNOS

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.