cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Scalar field cosmology modified by the Generalized Uncertainty Principle
Creators: name: Paliathanasis, Andronikos
name: Pan, Supriya
name: Pramanik, Souvik
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider quintessence scalar field cosmology in which the Lagrangian of the scalar field is modified by the Generalized Uncertainty Principle. We show that the perturbation terms which arise from the deformed algebra are equivalent with the existence of a second scalar field, where the two fields interact in the kinetic part. Moreover, we consider a spatially flat Friedmann-Lema\^ıtre-Robertson-Walker spacetime (FLRW), and we derive the gravitational field equations. We show that the modified equation of state parameter $w_{GUP}$ can cross the phantom divide line; that is $w_{GUP}
description: 12 pages; 3 figures; discussion improved; new references; accepted for publication by CQG
(401563) George Oliver
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Impact of ADC values in the prediction of distant metastasis in endometrial cancer
Creators: name: Tunçbilek, Nermin
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: Oncology
subject: MR
subject: MR-Diffusion/Perfusion
subject: Decision analysis
subject: Diagnostic procedure
subject: Cancer
subject: Neoplasia

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Endometrial carcinoma (EC) is the most common gynecological tumor in developed countries. Magnetic resonance imaging (MRI) has proven to be the most effective technique in the preoperative evaluation of endometrial cancer, showing great accuracy in...
N-glycosylation controls the function of junctional adhesion molecule-A
Creators: name: Graham, David M.
name: Bear, James E.
name: Wittchen, Erika
name: Scott, David W.
name: Burridge, Keith
name: Tolbert, Caitlin E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Junctional adhesion molecule-A (JAM-A) is an adherens and tight junction protein expressed by endothelial and epithelial cells. JAM-A serves many roles and contributes to barrier function and cell migration and motility, and it also acts as a ligand for the leukocyte receptor LFA-1. JAM-A is reported to contain N-glycans, but the extent of this modification and its contribution to the protein’s functions are unknown. We show that human JAM-A contains a single N-glycan at N185 and that this residue is conserved across multiple mammalian species. A glycomutant lacking all N-glycans, N185Q, is able to reach the cell surface but exhibits decreased protein half-life compared with the wild- type protein. N-glycosylation of JAM-A is required for the protein’s ability to reinforce barrier function and contributes to Rap1 activity. We further show that glycosylation of N185 is required for JAM-A–mediated reduction of cell migration. Finally, we show that N-glycosylation of JAM-A regulates leukocyte adhesion and LFA-1 binding. These findings identify N-glycosylation as critical for JAM-A’s many functions.
(401564) Peter Reid
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Speeding Up MCMC by Delayed Acceptance and Data Subsampling
Creators: name: Quiroz, Matias
name: Tran, Minh-Ngoc
name: Villani, Mattias
name: Kohn, Robert
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computation (stat.CO)
subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: The complexity of the Metropolis-Hastings (MH) algorithm arises from the requirement of a likelihood evaluation for the full data set in each iteration. Payne and Mallick (2015) propose to speed up the algorithm by a delayed acceptance approach where the acceptance decision proceeds in two stages. In the first stage, an estimate of the likelihood based on a random subsample determines if it is likely that the draw will be accepted and, if so, the second stage uses the full data likelihood to decide upon final acceptance. Evaluating the full data likelihood is thus avoided for draws that are unlikely to be accepted. We propose a more precise likelihood estimator which incorporates auxiliary information about the full data likelihood while only operating on a sparse set of the data. We prove that the resulting delayed acceptance MH is more efficient compared to that of Payne and Mallick (2015). The caveat of this approach is that the full data set needs to be evaluated in the second stage. We therefore propose to substitute this evaluation by an estimate and construct a state-dependent approximation thereof to use in the first stage. This results in an algorithm that (i) can use a smaller subsample m by leveraging on recent advances in Pseudo-Marginal MH (PMMH) and (ii) is provably within $O(m^{-2})$ of the true posterior.
description: Accepted for publication in Journal of Computational and Graphical Statistics
Prudenza, dovere di conoscenza e colpa penale. Proposta per un metodo di giudizio
Creators: name: Perin, Andrea
Publisher: name: Universit� degli Studi di Trento
Year: 2020

description: A quali condizioni una condotta che offende beni giuridici fondamentali, quali la vita e l'integrit� fisica della persona, pu� dirsi colposa per il diritto penale? Questo studio porta ad interrogarsi sul metodo di definizione del dovere di diligenza, nonch� sui criteri di giudizio in base ai quali esso pu� ritenersi inosservato, giustificandosi altres� l?imputazione di colpevolezza. Il limite della libert� di svolgere attivit� generalmente rischiose, ma socialmente utili, allo scopo di non arrecare danno ad altri, � segnato da un dovere di conoscenza. Specularmente, esso indica anche il limite della colpa, intesa come inosservanza lesiva di un'aspettativa normativa suggerita da una certa idea di prudenza. Il libro attraversa diversi scenari, dalla societ� del rischio novecentesca all'apparizione dell?intelligenza artificiale in medicina, offrendo una rinnovata riflessione sull?autonomia individuale e sul senso del principio di responsabilit� nella vita di relazione.
title: Night shift cerebral CT-scans: pitfalls to avoid for young radiologists
Creators: name: Noureddine, Leila
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: CNS
subject: Emergency
subject: Trauma
subject: CT
subject: Contrast agent-intravenous
subject: Diagnostic procedure
subject: Structured reporting
subject: Artifacts
subject: Education and training
subject: Quality assurance

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Cerebral CT-scans may be the most demanded radiological exams in emergency situations such as traumas, seizures, intracranial hypertension and consciousness disorders. They often are regarded as easy to interpret, which is a trap in which young...
Pat1 protects centromere-specific histone H3 variant Cse4 from Psh1-mediated ubiquitination
Creators: name: Dittman, Lauren E.
name: Haase, Julian
name: Mishra, Prashant K.
name: Yeh, Elaine
name: Basrai, Munira A.
name: Guo, Jiasheng
name: Bloom, Kerry
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: A novel Pat1-dependent mechanism is identified for the protection of kinetochore-associated Cse4 from ubiquitination in order to ensure faithful chromosome segregation and genomic stability.Evolutionarily conserved histone H3 variant Cse4 and its homologues are essential components of specialized centromere (CEN)-specific nucleosomes and serve as an epigenetic mark for CEN identity and propagation. Cse4 is a critical determinant for the structure and function of the kinetochore and is required to ensure faithful chromosome segregation. The kinetochore protein Pat1 regulates the levels and spatial distribution of Cse4 at centromeres. Deletion of PAT1 results in altered structure of CEN chromatin and chromosome segregation errors. In this study, we show that Pat1 protects CEN-associated Cse4 from ubiquitination in order to maintain proper structure and function of the kinetochore in budding yeast. PAT1-deletion strains exhibit increased ubiquitination of Cse4 and faster turnover of Cse4 at kinetochores. Psh1, a Cse4-specific E3-ubiquitin ligase, interacts with Pat1 in vivo and contributes to the increased ubiquitination of Cse4 in pat1∆ strains. Consistent with a role of Psh1 in ubiquitination of Cse4, transient induction of PSH1 in a wild-type strain resulted in phenotypes similar to a pat1∆ strain, including a reduction in CEN-associated Cse4, increased Cse4 ubiquitination, defects in spatial distribution of Cse4 at kinetochores, and altered structure of CEN chromatin. Pat1 interacts with Scm3 and is required for its maintenance at kinetochores. In conclusion, our studies provide novel insights into mechanisms by which Pat1 affects the structure of CEN chromatin and protects Cse4 from Psh1-mediated ubiquitination for faithful chromosome segregation.
Pheromone-induced morphogenesis and gradient tracking are dependent on the MAPK Fus3 binding to G
Creators: name: Ford, Eintou
name: Elston, Timothy C.
name: Vered, Lior
name: Pena, Matthew I.
name: Errede, Beverly
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Mitogen-activated protein kinase (MAPK) pathways control many cellular processes, including differentiation and proliferation. These pathways commonly activate MAPK isoforms that have redundant or overlapping function. However, recent studies have revealed circumstances in which MAPK isoforms have specialized, nonoverlapping roles in differentiation. The mechanisms that underlie this specialization are not well understood. To address this question, we sought to establish regulatory mechanisms that are unique to the MAPK Fus3 in pheromone-induced mating and chemotropic fate transitions of the budding yeast Saccharomyces cerevisiae. Our investigations reveal a previously unappreciated role for inactive Fus3 as a potent negative regulator of pheromone-induced chemotropism. We show that this inhibitory role is dependent on inactive Fus3 binding to the α-subunit of the heterotrimeric G-protein. Further analysis revealed that the binding of catalytically active Fus3 to the G-protein is required for gradient tracking and serves to suppress cell-to-cell variability between mating and chemotropic fates in a population of pheromone-responding cells.
Mathematical modeling of prostate cancer immunotherapy
Creators: name: Coletti, Roberta
Publisher: name: Universit� degli studi di Trento
Year: 2020

description: Immunotherapy, by enhancing the endogenous anti-tumor immune responses, is showing promising results for the treatment of numerous cancers refractory to conventional therapies. However, its effectiveness for advanced castration-resistant prostate cancer remains unsatisfactory and new therapeutic strategies need to be developed. To this end, mathematical modeling provides a quantitative framework for testing in silico the efficacy of new treatments and combination therapies, as well as understanding unknown biological mechanisms. In this dissertation we present two mathematical models of prostate cancer immunotherapy defined as systems of ordinary differential equations. The first work, introduced in Chapter 2, provides a mathematical model of prostate cancer immunotherapy which has been calibrated using data from pre-clinical experiments in mice. This model describes the evolution of prostate cancer, key components of the immune system, and seven treatments. Numerous combination therapies were evaluated considering both the degree of tumor inhibition and the predicted synergistic effects, integrated into a decision tree. Our simulations predicted cancer vaccine combined with immune checkpoint blockade as the most effective dual-drug combination immunotherapy for subjects treated with androgen-deprivation therapy that developed resistance. Overall, this model serves as a computational framework to support drug development, by generating hypotheses that can be tested experimentally in pre-clinical models. The Chapter 3 is devoted to the description of a human prostate cancer mathematical model. The potential effect of immunotherapies on castration-resistant form has been analyzed. In particular, the model includes the dendritic vaccine sipuleucel-T, the only currently available immunotherapy option for advanced prostate cancer, and the ipilimumab, a drug targeting the cytotoxic T-lymphocyte antigen 4 , exposed on the CTLs membrane, currently under Phase II clinical trial. From a mathematical analysis of a simplified model, it seems likely that, under continuous administration of ipilimumab, the system lies in a bistable situation where both the no-tumor equilibrium and the high-tumor equilibrium are attractive. The schedule of periodic treatments could then determine the outcome, and mathematical models could help in deciding an optimal schedule.
Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK
Creators: name: Dohlman, Henrik G.
name: McCarter, Patrick C.
name: Nagiec, Michal J.
name: Elston, Timothy C.
name: Dixit, Gauri
name: Kelley, Joshua B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: MAPKs are activated by dual phosphorylation. Much of the MAPK Fus3 is monophosphorylated and acts to inhibit signaling in vivo. Computational models reveal how a kinase scaffold and phosphatase act together to dynamically regulate dual-phosphorylated and monophosphorylated MAPKs and the downstream signal.Protein kinases regulate a broad array of cellular processes and do so through the phosphorylation of one or more sites within a given substrate. Many protein kinases are themselves regulated through multisite phosphorylation, and the addition or removal of phosphates can occur in a sequential (processive) or a stepwise (distributive) manner. Here we measured the relative abundance of the monophosphorylated and dual-phosphorylated forms of Fus3, a member of the mitogen-activated protein kinase (MAPK) family in yeast. We found that upon activation with pheromone, a substantial proportion of Fus3 accumulates in the monophosphorylated state. Introduction of an additional copy of Fus3 lacking either phosphorylation site leads to dampened signaling. Conversely, cells lacking the dual-specificity phosphatase (msg5Δ) or that are deficient in docking to the MAPK-scaffold (Ste5ND) accumulate a greater proportion of dual-phosphorylated Fus3. The double mutant exhibits a synergistic, or “synthetic,” supersensitivity to pheromone. Finally, we present a predictive computational model that combines MAPK scaffold and phosphatase activities and is sufficient to account for the observed MAPK profiles. These results indicate that the monophosphorylated and dual-phosphorylated forms of the MAPK act in opposition to one another. Moreover, they reveal a new mechanism by which the MAPK scaffold acts dynamically to regulate signaling.
(401560) James Miller
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Food Cost Review, 1990.
Creators: name: Dunham, Denis
name: Dunham, Denis
Publisher: name: Unknown
Year: 1991
Subjects: subject: Agricultural and Food Policy
subject: Demand and Price Analysis
subject: Marketing
subject: FOS: Economics and business
subject: Retail food prices
subject: farm-to-retail price spread
subject: farm value share
subject: food marketing costs
subject: food spending
subject: profit
subject: productivity

description: Food prices, as measured by the Consumer Price Index (CPI), increased 5.8 percent in 1990, the same percentage increase as the year before. Higher farm prices and charges for processing and distribution both contributed to the price increase. The prices farmers received for commodities, as measured by the farm value of USDAs market basket of foods, also rose 5.8 percent. But the increase in farm value was smaller than the 7.1-percent rise in retail prices of these foods in 1990. (The 7.1-percent market basket increase excludes away-from-home meals and includes fewer commodities compared with the 5.8-percent CPI all-food index.) The farm value share of the food dollar spent in grocery stores in 1990 was 30 percent, unchanged from 1989. The farm-to-retail price spread of USDA's market basket of foods rose 7.7 percent, reflecting higher prices of inputs, such as labor and energy, that the food industry used.
title: Ultrasound of the patient with acute scrotal pain at the emergency department – A Pictorial Review
Creators: name: Fernandes, Diogo
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Emergency
subject: Genital / Reproductive system male
subject: Ultrasound
subject: Ultrasound-Colour Doppler
subject: Ultrasound-Spectral Doppler
subject: Education
subject: Technical aspects
subject: Acute
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: - Understand the role of the ultrasound in the diagnosis of the patient with acute scrotal pain. - Understand the normal scrotal ultrasound. - Know the main scrotal pathologies in an emergency context and their sonographic...
Structural basis for recognition of the Sec4 Rab GTPase by its effector, the Lgl/tomosyn homologue, Sro7
Creators: name: Rossi, Guendalina
name: Temple, Brenda
name: Watson, Kelly
name: Brennwald, Patrick
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Members of the tomosyn/Lgl/Sro7 family play important roles in vesicle trafficking and cell polarity in eukaryotic cells. The yeast homologue, Sro7, is believed to act as a downstream effector of the Sec4 Rab GTPase to promote soluble N-ethylmaleimide–sensitive factor adaptor protein receptor (SNARE) assembly during Golgi-to–cell surface vesicle transport. Here we describe the identification of a Sec4 binding site on the surface of Sro7 that is contained within a cleft created by the junction of two adjacent β-propellers that form the core structure of Sro7. Computational docking experiments suggested four models for interaction of GTP-Sec4 with the Sro7 binding cleft. Further mutational and biochemical analyses confirmed that only one of the four docking arrangements is perfectly consistent with our genetic and biochemical interaction data. Close examination of this docking model suggests a structural basis for the high substrate and nucleotide selectivity in effector binding by Sro7. Finally, analysis of the surface variation within the homologous interaction site on tomosyn-1 and Lgl-1 structural models suggests a possible conserved Rab GTPase effector function in tomosyn vertebrate homologues.
title: Pearls and pitfalls of 8th edition TNM staging for lung cancer
Creators: name: Singh, Aparajita
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Anatomy
subject: Lung
subject: Lymph nodes
subject: CT
subject: CT-High Resolution
subject: PET-CT
subject: Education
subject: Staging
subject: Structured reporting
subject: Cancer
subject: Multidisciplinary cancer care

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: In 2017, the TNM staging for lung cancer was upgraded to the 8th TNM classification. Awareness of pearls and pitfalls in 8th edition of TNM staging for lung cancer will help in better and more accurate diagnosis and...
A Drosophila Model of Spinal Muscular Atrophy Uncouples snRNP Biogenesis Functions of Survival Motor Neuron from Locomotion and Viability Defects
Creators: name: Wen, Ying
name: Matera, A. Gregory
name: Praveen, Kavita
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The Spinal Muscular Atrophy (SMA) protein, survival motor neuron (SMN), functions in the biogenesis of small nuclear ribonucleoproteins (snRNPs). SMN has also been implicated in tissue-specific functions, however, it remains unclear which of these is important for the etiology of SMA. Smn null mutants are larval lethals and show significant locomotion defects as well as reductions in minor-class spliceosomal snRNAs. Despite these reductions, we found no appreciable defects in splicing of mRNAs containing minor-class introns. Transgenic expression of low levels of either wild-type or an SMA patient-derived form of SMN rescued the larval lethality and locomotor defects, however, snRNA levels were not restored. Thus, the snRNP biogenesis function of SMN is not a major contributor to the phenotype of Smn null mutants. These findings have major implications for SMA etiology because they show that SMN's role in snRNP biogenesis can be uncoupled from the organismal viability and locomotor defects.
title: Management of Solid Renal Masses: the role of the Radiologist
Creators: name: Di Giusto, Anna
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: Kidney
subject: CT
subject: MR
subject: Ultrasound
subject: Ablation procedures
subject: Biopsy
subject: Contrast agent-intravenous
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Explain the role of the radiologist in the management of solid renal masses from diagnosis with Ultrasound (US), Contrast-Enhanced Computed Tomography (CE-CT), Magnetic Resonance Imaging (MRI) and percutaneous biopsy, to treatment with active...
A Revisit to Non-maximally Entangled Mixed States: Teleportation Witness, Noisy Channel and Discord
Creators: name: Roy, Sovik
name: Ghosh, Biplab
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We constructed a class of non-maximally entangled mixed states \cite{roy2010} and extensively studied its entanglement properties and also their usefulness as teleportation channels. In this article, we revisited our constructed state and have studied it from three different perspectives. Since every entangled state is associated with an witness operator, we have found a suitable entanglement as well as teleportation witness for our non-maximally entangled mixed states. We considered the noisy channel's effects on our constructed state and to see whether it affects the states' capacity as teleportation channel. For this purpose we have mainly emphasized on amplitude damping channel. A comparative study with concurrence and quantum discord of the state of ref. \cite{roy2010} has also been carried out here.
description: 11 pages, 4 figures
A Resource for Manipulating Gene Expression and Analyzing cis-Regulatory Modules in the Drosophila CNS
Creators: name: Roberts, Jourdain
name: Lupton, Josh R.
name: Pollard, Jill L.
name: Tran, Khoa D.
name: Bauer, David M.
name: Kohwi, Minoree
name: Tanner, Stephanie
name: Pearson, Joseph C.
name: Heckscher, Ellie S.
name: Lai, Sen Lin
name: Bennett, Alysha L.
name: Doan, Phuong Nam
name: Rubin, Gerald M.
name: Doe, Chris Q.
name: Kroll, Jason R.
name: Dyukareva, Anna V.
name: Crews, Stephen T.
name: Laverty, Todd R.
name: Strader, Marie E.
name: Purice, Maria D.
name: Wilbur, Allison N.
name: Manning, Laurina
name: Kelly, Jimmy J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Here we describe the embryonic CNS expression of 5,000 GAL4 lines made using molecularly defined cis-regulatory DNA inserted into a single attP genomic location. We document and annotate the patterns in early embryos when neurogenesis is at its peak, and in older embryos where there is maximal neuronal diversity and the first neural circuits are established. We note expression in other tissues such as the lateral body wall (muscle, sensory neurons, trachea) and viscera. Companion papers report on the adult brain and larval imaginal discs, and the integrated datasets are available online (www.janelia.org/flylight/gal4-gen1). This collection of embryonically-expressed GAL4 lines will be valuable for determining neuronal morphology and function; the 1862 lines expressed in small subsets of neurons (<20/segment) will be especially valuable for characterizing interneuronal diversity and function, as interneurons comprise the majority of all CNS neurons, yet their gene expression profile and function remain virtually unexplored.
title: Cystic pancreatic masses: the fundamentals
Creators: name: Noureddine, Leila
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: Oncology
subject: CT
subject: MR
subject: MR-Cholangiography
subject: Contrast agent-intravenous
subject: Diagnostic procedure
subject: eLearning
subject: Cancer
subject: Cysts

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Cystic pancreatic masses are a frightening theme for many young radiologists, due to the variety of possible etiologies, whether they be benign or malign. Our purpose is to demystify them by showing an expressive iconography and the simplest...
(401561) Charles Cowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Food Marketing Review, 1991
Creators: name: Economic Research Service, USDA
name: Economic Research Service, USDA
Publisher: name: Unknown
Year: 1992
Subjects: subject: Food Consumption/Nutrition/Food Safety
subject: Industrial Organization
subject: Marketing
subject: FOS: Economics and business

description: Retail sales of the U.S. food marketing system were flat in 1990 and declined in 1991, after adjustments for price increases, due to the recession. Nevertheless, food manufacturers and retailers showed continued increases in profitability from operations (excluding interest expense), reflecting wage and producer price stability and streamlining of operations. Food manufacturing and retailing continue to be among the most highly leveraged U.S. industries because of large leveraged buyouts in the late 1980's. Mergers and leveraged buyout transactions fell sharply in 1990 and 1991 from the phenomenal levels of recent years in both volume and value. Competition among larger and fewer firms for a share of the food dollar and limited shelf space was reflected in record new product introductions, consumer advertising expenditures, and retail promotions, including payments to retailers to stock new products. But even in some highly concentrated industries, price discounts appeared prevalent. The system's performance continued its spectacular strength of recent years as reflected in increased globalization, higher levels of new plant and equipment expenditures, and outstanding performance for common stock owners.
title: Interstitial lung disease in rheumatoid arthritis: what's new?
Creators: name: Cayón Somacarrera, Silvia
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Lung
subject: Thorax
subject: CT
subject: CT-High Resolution
subject: Education
subject: Screening
subject: Connective tissue disorders
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To review the different types of interstitial pneumonia associated with rheumatoid arthritis using high-resolution CT (HRCT). To discuss the proposed changes by the Fleischner Society Idiopathic Pulmonary Fibrosis Guideline to optimize the diagnosis...
CNAF experience in support of the JUNO distributed computing model
Creators: name: Rendina, Andrea
name: Morganti, Lucia
name: Zani, Stefano
name: De Girolamo, Donato
name: Chiarelli, Lorenzo
name: Fornari, Federico
Publisher: name: Zenodo
Year: 2023

description: The Italian WLCG Tier-1 located in Bologna and managed by INFN CNAF provides computing and storage resources to several research communities in the fields of High-Energy Physics, Astroparticle Physics, Gravitational Waves, Nuclear Physics and others. Among them, the Jiangmen Underground Neutrino Observatory (JUNO), devoted to the construction and operation of a neutrino detector located underground in Kaiping, Jiangmen in Southern China, will employ a computing infrastructure geographically distributed in Chinese, Russian, French and Italian datacenters. The detector data rate is expected to be of the order of 2 PB per year, continuously transferred from the detector site to the INFN Tier-1 in Italy. To guarantee the optimal operations among all the aforementioned sites, a series of periodic network and data management challenges have been performed.
 In this talk, the technologies involved to set up the cross-continent data transfer (e.g. StoRM WebDAV, EOS, dCache, XrootD, FTS, Rucio) are presented, together their performance. The presentation was given in the Data Management & Big Data track of ISGC 2023.
Time-variable non-thermal emission in the planetary nebula IRAS 15103-5754
Creators: name: Suarez, Olga
name: Gomez, Jose F.
name: Bendjoya, Philippe
name: Miranda, Luis F.
name: Guerrero, Martin A.
name: Uscanga, Lucero
name: Green, James A.
name: Rizzo, J. Ricardo
name: Ramos-Larios, Gerardo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The beginning of photoionization marks the transition between the post-Asymptotic Giant Branch (post-AGB) and planetary nebula (PN) phases of stars with masses < 8 M_sun. This critical phase is difficult to observe, as it lasts only a few decades. The combination of jets and magnetic fields, the key agents of PNe shaping, could give rise to synchrotron emission, but this has never been observed before in any PNe, since free-free emission from the ionized gas is expected to dominate its radio spectrum. In this paper we report radio continuum observations taken with the Australia Telescope Compact Array between 1 and 46 GHz of the young PN IRAS 15103-5754. Our observations in 2010-2011 show non-thermal emission compatible with synchrotron emission from electrons accelerated at a shock with spectral index $α\simeq -0.54$. However, in 2012, the spectral index $α\simeq -0.28$ is no longer compatible with synchrotron emission in these types of processes. Several hypothesis are discussed to explain this change. The more plausible ones are related to the presence of the newly photoionized region in this young PN: either energy loss of electrons due to Coulomb collisions with the plasma, or selective suppression of synchrotron radiation due to the Razin effect. We postulate that the observed flattening of non-thermal radio spectra could be a hallmark identifying the beginning of the PN phase.
description: To be published in The Astrophysical Journal. 9 pages, 3 figures
title: Obliterative peripheral arteriopathy: improving Doppler ultrasound practice in order to minimize radiation
Creators: name: Noureddine, Leila
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Arteries / Aorta
subject: Extremities
subject: Vascular
subject: CT-Angiography
subject: Ultrasound-Colour Doppler
subject: Ultrasound-Spectral Doppler
subject: Diagnostic procedure
subject: Structured reporting
subject: Technical aspects
subject: Education and training
subject: Obstruction / Occlusion

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Obliterative peripheral arteriopathy is a common issue among elderly patients, especially in chronic smokers or diabetic subjects. Its main imaging modalities are Doppler ultrasound and angio-CT scan. Our aim is to remind young radiologists how to...
title: Morphologic and functional MRI features of intra-cranial tuberculoma: a pictorail study.
Creators: name: Belhadj, Mohamed
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: CNS
subject: Neuroradiology brain
subject: MR
subject: MR-Functional imaging
subject: Imaging sequences
subject: Infection

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To describe MRI morphologic and functional features of intra-cranial...
Additional file 1 of Drug-drug interaction assessment based on a large-scale spontaneous reporting system for hepato- and renal-toxicity, and thrombocytopenia with concomitant low-dose methotrexate and analgesics use
Creators: name: Honma, Takeshi
name: Onda, Kenji
name: Masuyama, Koichi
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Supplementary Material 1
title: Value of CT-angiography in prediction of treatment outcomes in patients with acute and chronic critical lower limb ischemia.
Creators: name: Panyukova, Alexandra
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Arteries / Aorta
subject: Emergency
subject: Vascular
subject: CT-Angiography
subject: Angioplasty
subject: Arterial access
subject: Ischaemia / Infarction

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Peripheral artery disease (PAD) is defined as a partial or complete obstruction of any part of the peripheral arterial tree and is typically associated with the lower extremities. Degree of occlusions and stenosis of lower limb arterial vessels...
(401562) Edward Cowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Investigating the Influence of Stance Label Explanations on Click Diversity in Web Search
Creators: name: Zhangyi Wu
name: Rieger, Alisa
name: Cau, Federico M.
name: Draws, Tim
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Physical Sciences and Mathematics
subject: Computer Sciences
subject: Graphics and Human Computer Interfaces

description: Preregistering our upcoming user study.
title: MRI findings of brain lesions in hypernatremic osmotic disturbances.
Creators: name: Ben Fatma, Abderraouf
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Neuroradiology brain
subject: MR
subject: Laboratory tests
subject: Endocrine disorders

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To illustrate the neuroradiologic presentations of brain injury in the framework of acute hypernatremia.To enlist the various causes of the osmotic demyelination...
Black hole critical behaviour with the generalized BSSN formulation
Creators: name: Akbarian, Arman
name: Choptuik, Matthew W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The development of hyperbolic formulations of Einstein's equations has revolutionized our ability to perform long-time, stable, accurate numerical simulations of strong field gravitational phenomena. However, hyperbolic methods have seen relatively little application in one area of interest, type II critical collapse, where the challenges for a numerical code are particularly severe. Using the critical collapse of a massless scalar field in spherical symmetry as a test case, we study a generalization of the Baumgarte-Shapiro-Shibata-Nakamura (BSSN) formulation due to Brown that is suited for use with curvilinear coordinates. We adopt standard dynamical gauge choices, including 1+log slicing and a shift that is either zero or evolved by a Gamma-driver condition. With both choices of shift we are able to evolve sufficiently close to the black hole threshold to (1) unambiguously identify the discrete self-similarity of the critical solution (2) determine an echoing exponent consistent with previous calculations and (3) measure a mass scaling exponent, also in accord with prior computations. Our results can be viewed as an encouraging first step towards the use of hyperbolic formulations in more generic type II scenarios, including the as yet unresolved problem of critical collapse of axisymmetric gravitational waves.
description: Minor revisions in response to referee's comments
Sudden death and rebirth of Entanglement for Different Dimensional Systems driven by a Classical Random External Field
Creators: name: Metwally, N.
name: Eleuch, H.
name: Obada, A. -S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The entangled behavior of different dimensional systems driven by classical external random field is investigated. The amount of the survival entanglement between the components of each system is quantified. There are different behaviors of entanglement that come into view decay, sudden death, sudden birth and long-lived entanglement. The maximum entangled states which can be generated from any of theses suggested systems are much fragile than the partially entangled ones. The systems of larger dimensions are more robust than those of smaller dimensions systems, where the entanglement decay smoothly, gradually and may vanish for a very short time. For the class of $2\times 3$ dimensional system, the one parameter family is found to be more robust than the two parameters family. Although the entanglement of driven $ 2 \times 3$ dimensional system is very sensitive to the classical external random field, one can use them to generate a long-lived entanglement.
Unusual plastic deformation and damage features in Titanium: experimental tests and constitutive modeling
Creators: name: Revil-Baudard, Benoit
name: Cazacu, Oana
name: Flater, Philip
name: Chandola, Nitin
name: Alves, J. L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences
subject: 74CXX, 74RXX

description: In this paper, we present an experimental study on plastic deformation and damage of polycrystalline pure Ti, as well as modeling of the observed behavior. From the mechanical characterization data, it can be concluded that the material displays anisotropy and tension-compression asymmetry. As concerns damage, the X-ray tomography measurements conducted reveal that damage distribution and evolution in this HCP Ti material is markedly different than in a typical FCC material such as copper. Stewart and Cazacu (2011) anisotropic elastic/plastic damage model is used to describe the behavior. All material parameters involved in this model have a clear physical significance, being related to plastic properties, and are determined based on very few simple mechanical tests. It is shown that this model predicts correctly the anisotropy in plastic deformation, and its strong influence on damage distribution and damage accumulation in Ti. Specifically, for a smooth axisymmetric specimen subject to uniaxial tension, damage initiates at the center of the specimen and is diffuse; the level of damage close to failure is very low. On the other hand, for a notched specimen subject to the same loading, the model predicts that damage initiates at the outer surface of the specimen, and further grows from the outer surface to the center of the specimen, which corroborates with the in-situ tomography data.
Annuncio morte della contessa Elisabetta Fiorini, vedova Mazzanti (23 aprile 1879)
Creators: name: Fiorini Mazzanti, Elisabetta
Publisher: name: Zenodo
Year: 2022
Subjects: Accademia dei Georgofili
Fiorini Mazzanti, Elisabetta
Necrologi
1879
Donne
Scienziate
Pregiudizi

description: Annuncio morte di Elisabetta Fiorini Mazzanti del 23 aprile 1879. Segnatura dell’unità documentale: Archivio storico dell’Accademia dei Georgofili, Carteggio, Busta 37, 5149. Natura: a stampa. Consistenza: [1] carta
description: Digitalizzato come parte della Mostra virtuale: Riconoscere il merito, superare i pregiudizi: scienziate ai Georgofili (1753-1911). https://www.georgofili.it/contenuti/riconoscere-il-merito-superare-i-pregiudizi-scienziate-ai-georgofili-1753-1911-mostra-in-rete/11369
Cryptopatches Are Essential for the Development of Human GALT
Creators: name: Denton, Paul W.
name: Garcia, J. Victor
name: Nochi, Tomonori
name: Wahl, Angela
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Abnormal gut-associated lymphoid tissue (GALT) in humans is associated with infectious and autoimmune diseases, which cause dysfunction of the gastrointestinal (GI) tract immune system. To aid in investigating GALT pathologies in vivo, we bioengineered a human-mouse chimeric model characterized by the development of human GALT structures originating in mouse cryptopatches. This novel observation represents a fundamental breakthrough in our mechanistic understanding of the role of cryptopatches in human GALT genesis and emphasizesthe evolutionary conservation of this developmental process between humans and mice. Immunoglobulin class switching to IgA occurs in these GALT structures leading to numerous human IgA-producing plasma cells throughout the intestinal lamina propria. CD4+ T cell depletion within GALT structures results from HIV infection, as in humans. This human-mouse chimeric model represents the most comprehensive experimental platform currently available for the study and the pre-clinical efficacy testing of therapeutics designed to repair disease-damaged GALT.
Food Cost Review, 1991
Creators: name: Dunham, Denis
name: Dunham, Denis
Publisher: name: Unknown
Year: 1992
Subjects: subject: Agricultural and Food Policy
subject: Demand and Price Analysis
subject: Marketing
subject: FOS: Economics and business
subject: Retail food prices
subject: farm-to-retail price spread
subject: farm value share
subject: food marketing costs
subject: food spending
subject: profit
subject: productivity

description: Food prices, as measured by the Consumer Price Index (CPI), increased 2.9 percent in 1991, half the 1990 price increase of 5.8 percent. Higher charges for processing and distribution mainly accounted for the price increase. The farm-to-retail price spread of USDA's market basket of foods rose 6.7 percent, partly reflecting higher prices of inputs, such as labor and energy, that the food industry used. The prices farmers received for commodities, as measured by the farm value of USDA's market basket of foods, declined 6.2 percent. The farm value share of the food dollar spent in grocery stores in 1991 was 27 percent, down from 30 percent in 1990.