cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Study of psychosocial factors and endothelial dysfunction in coronary heart disease patients
Creators: name: Tang, Nan
name: Li, Kangming
name: Zhang, Qingdui
name: Sun, Huamei
name: Peng, Cheng
name: Hao, Ji
name: Qi, Chunmei
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Science Policy
subject: Mental Health

description: To provide valuable insight into the prevention and treatment of coronary heart disease, this study aimed to explore the association between psychosocial elements and endothelial dysfunction in diagnosed patients. Using a cross-sectional study design, we selected patients with coronary heart disease who visited the cardiology department of our hospital from January to December 2021. According to coronary angiography results, patients were divided into the coronary stenosis group (≥50%) and the normal coronary group (<50%), with 100 cases in each group. We assessed the levels of psychosocial factors using the Type A Behaviour Pattern Scale (TABP), Self-Rating Anxiety Scale (SAS), Social Support Rating Scale (SSRS), and Self-Rating Depression Scale (SDS). Endothelial synthesis of nitric oxide (NOx) and endothelium-dependent (EDF) and endothelium-independent (NEDF) vasodilation functions were measured and compared using enzyme-linked immunosorbent assay (ELISA) and colour Doppler ultrasonography, respectively. Patients in the coronary stenosis group had significantly higher scores in Type A behaviour, anxiety, and depression and significantly lower scores in social support compared with the normal coronary group (t = 3.21, 4.15, 3.87; p < 0.05; t = −2.96; p < 0.05). EDF, NEDF, and NOx levels were significantly lower in the coronary stenosis group than in the normal coronary group (t = −4.32, −3.76, −4.67; p < 0.05). Psychosocial factors were negatively correlated with endothelial function indices (r = −0.31 to −0.48; p < 0.05). Multiple linear regression analysis revealed that Type A behavioural anxiety, depression, and social support were independent risk factors influencing endothelial dysfunction (β = −0.23, −0.26, −0.21, −0.19; p < 0.05). A close relationship was observed between psychosocial factors and endothelial dysfunction in patients with coronary heart disease. Assessment and intervention of psychosocial factors in these patients should be strengthened to improve endothelial function and reduce the risk of cardiovascular events.
Stroke-Associated Differences in Rates of Activity of Daily Living Loss Emerge Years Before Stroke Onset
Creators: name: Liu, Sze Y.
name: Capistrant, Benjamin D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: To compare typical age-related changes in activities of daily living (ADL) independence in stroke-free adults to long-term ADL trajectories before and after stroke.
Räume der Erkenntnis. Zur Raummetaphorik in der augustinischen Erkenntnistheorie
Creators: name: Fuhrer, Therese
Publisher: name: Edition Topoi
Year: 2016

description: Bei der Beschreibung kognitiver Prozesse, in denen die Erkenntnis einer ‚höchsten‘ oder ‚göttlichen‘ Wahrheit vermittelt werden soll, greifen antike philosophische Texte oft auf räumliche Metaphern zurück, mit denen sie diesen Vorgang im ‚Innern‘ des Menschen lokalisieren. Hier interessiert die Frage, mit welchen Raummetaphern Augustin die Erkenntnisprozesse in De trinitate beschreibt. Augustin geht davon aus, dass der Mensch nach Genesis 1,27 „nach Gottes Ebenbild“ geschaffen und daher die imago dei als eine Art Struktur im ‚inneren Menschen‘ präsent seien. Aus der ‚Vermischung‘ (blending) des nicht-metaphorischen Konzepts des Gottesbildes mit dem durch Raummetaphern beschriebenen Menschenbild entwickelt Augustin seine – in der antiken Erkenntnistheorie neue und einzigartige, auch wirkungsmächtige – ‚theologische Epistemologie‘ und eine ‚Onto-Theologie des Bildes‘.
Circular Economy Practices in Supply Chains of Bangladesh
Creators: name: Bushra Jahan Noha
name: Arif Ali
name: Payal Kumari Shah
name: Pramita Tamang
name: Nusrat Jahan Khan
Publisher: name: BIHRM Supply Chain
Year: 2023

description: Circular economy practices offer a number of potential benefits for businesses and society, including reduced waste, increased resource efficiency, and job creation. However, there are also a number of challenges to integrating circular practices into supply chains, particularly in developing countries like Bangladesh. This paper investigates the challenges and opportunities of integrating circular economy practices into supply chains in Bangladesh.
The paper identifies a number of economic, regulatory, social, and cultural factors that can affect the adoption of circular practices. Economic factors, such as the cost of implementing circular practices and the availability of government subsidies, can play a significant role in the decision to adopt circular practices. Regulatory factors, such as environmental regulations and waste management policies, can also influence the adoption of circular practices. Social and cultural factors, such as consumer awareness of circular practices and the willingness of businesses to collaborate with suppliers and customers, can also play a role.
The paper also provides recommendations for businesses, policymakers, and stakeholders on how to navigate the complexities of adopting circular practices in Bangladesh. Businesses are encouraged to develop circular economy strategies and to collaborate with suppliers and customers to implement circular practices. Policymakers are encouraged to develop supportive policies and regulations that promote the adoption of circular practices. Stakeholders, such as NGOs and academic institutions, can play a role in raising awareness of circular practices and supporting businesses and policymakers in their efforts to adopt circular practices.
Overall, this paper provides a valuable overview of the challenges and opportunities of integrating circular economy practices into supply chains in Bangladesh. The paper's recommendations can help businesses, policymakers, and stakeholders to navigate the complexities of adopting circular practices and to realize the potential benefits of a circular economy.
Mild Cognitive Dysfunction Does Not Affect Diabetes Mellitus Control in Minority Elderly Adults
Creators: name: Teresi, Jeanne
name: Luchsinger, Jose A.
name: Weinstock, Ruth S.
name: Palta, Priya
name: Palmas, Walter
name: Shea, Steven
name: Golden, Sherita H.
name: Manly, Jennifer J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: To determine whether older adults with type 2 diabetes mellitus and cognitive dysfunction have poorer metabolic control of glycosylated hemoglobin, systolic blood pressure, and low-density lipoprotein cholesterol than those without cognitive dysfunction.
Risk of Pneumonia in New Users of Cholinesterase Inhibitors for Dementia
Creators: name: Kao Yang, Yea-Huei
name: Zhang, Yinghong
name: Iwata, Isao
name: Hsieh, Cheng-Yang
name: Setoguchi, Soko
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: To compare the risk of pneumonia among older patients receiving donepezil, galantamine, or rivastigmine for dementia.
Memoria sulla maniera di rendere atti alla nutrizione i grani fermentati / Vincenzio Chiarugi
Creators: name: Chiarugi, Vincenzo (Vincenzio)
Publisher: name: Zenodo
Year: 2023
Subjects: Accademia dei Georgofili
Vincenzo (Vincenzio) Chiarugi
Storia dell'agricoltura
Toscana
History of agriculture
Tuscany
History of science
Cereali

description: Memoria di Vincenzo (Vincenzio) Chiarugi del 3 giugno 1795. Segnatura dell’unità documentale: Archivio storico dell’Accademia dei Georgofili, Letture, memorie, rapporti e discussioni pubbliche, Busta 59, 176. Natura: manoscritto. Consistenza: cc. 12
description: Digitalizzato come parte della mostra virtuale: Vincenzio Chiarugi: agricoltura, ambiente e medicina nell'opera di un Georgofilo. Spunti per un percorso di ricerca e risorse in rete. https://www.georgofili.it/contenuti/vincenzio-chiarugi-agricoltura-ambiente-e-medicina-nellopera-di-un-georgofilo-spunti-per-un-percorso/8188
Supply Chain Modelling of Daily Consumed Cereal Grain in Bangladesh
Creators: name: Ankon Dey
name: Jawata Afnan
name: Naymul Hasan Nayem
name: Arindam Dey
name: Fariha Tanha Tonu
Publisher: name: BIHRM Supply Chain
Year: 2023

description: Supply Chain of Rice, Wheat, Corn as in Cereal Grains in Bangladesh are in focus for considerations of food security and climate change impacts. The presence of price volatility, characterized by rapid and unpredictable price fluctuations, further compounds the challenges faced by Bangladesh's supply chain for these commodities. This volatility can stem from a complex interplay of factors, including changes in global demand patterns, geopolitical events, weather-related disruptions, and speculative trading activities. Such fluctuations introduce uncertainty into market dynamics, rendering both producers and consumers vulnerable to adverse economic consequences. This research paper introduces a system dynamics model that focuses on the supply chain of cereal grain products, including rice, wheat, corn and others. The aim is to analyze and manage various scenarios related to supply chain management, extending from farmers to consumers. The goal is to devise effective and sustainable strategies for ensuring the accessibility of these commodities to consumers in Bangladesh. This involves designing policies that optimize supply chain efficiency while considering economic factors and uncertainties. In this paper we analyze how changes in productivity occur during seasonal production, what changes the lead time, and how changes in the variations in demand affect the performance of the supply chain. Drying these crops at the start and maintaining year-round operation of processing facilities can also help stabilize inventory and the overall supply chain for these products. This approach can enhance efficiency and reduce supply chain disruptions for various essential crops. Also, less total supply chain cost from economic operation results in less fuel consumption and hence less contribution to global warming. The model can pinpoint and analyze the most important parts of the supply chain. This helps in building a network that is both efficient and sustainable.
Diasporic Lag in Memory-Making: Chinese American Historiographies of the Second Sino-Japanese War
Creators: name: Chen, Ana
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: subject: Sino-Japanese War (1937-1945)
subject: Collective memory
subject: Chinese Americans
subject: Collective trauma
subject: World War II

description: How do diaspora communities construct histories of their homelands? My thesis compares diaspora and homeland understandings of a single historical moment: Japanese atrocities committed on Chinese soil and to Chinese peoples during the Second Sino-Japanese War. While the literature on collective memory and intergenerational trauma focuses attention on temporal inheritances of memory, few have considered how memory may be crystallized and transmitted across space, from homelands to diaspora. While traveling through China in 2021, I observed that second-generation Chinese Americans (those born in the United States) harbored greater and less nuanced forms of anti-Japanese anger than mainland Chinese youth of the same age, despite the former’s spatial and temporal distance from the mainland. Through both an original survey study and in-depth interviews, this thesis assesses whether these differences in historical memory are observed across a broader and more representative population, and also investigates the causes behind these differences in historical memory. Survey data demonstrates that third-generation Chinese Americans tend to hold greater degrees of anti-Japanese anger than do their first- and second-generation counterparts, and that second-generation Chinese Americans tend to hold different forms of anti-Japanese anger according to the year of their parents’ migration. Interview data suggests that several factors contribute to this difference, including a drive among second- and third-generation Chinese Americans to retrieve knowledge of Chinese history and heritage; a tendency among first-generation parents to educate their second-generation children with outdated historical narratives; and the surprising salience of mainland war films in Chinese American understandings of the war. However, survey and interview data indicate that Chinese Americans’ experiences with alienation, racism, and outsidership in the U.S. lead them to question both U.S. and Chinese narratives of the war, and to extend sympathy towards the contemporary Japanese people. Ultimately, this thesis documents how diasporic communities preserve, distort, and construct memories, with an agency that is often discounted in broader geopolitical discourse.
Speciation analysis of arsenic in biological matrices by automated hydride generation-cryotrapping-atomic absorption spectrometry with multiple microflame quartz tube atomizer (multiatomizer)
Creators: name: Adair, Blakely M.
name: Hernández-Zavala, Araceli
name: Thomas, David J.
name: Drobná, Zuzana
name: Matoušek, Tomáš
name: Dědina, Jiří
name: Stýblo, Miroslav
name: Paul, David S.
name: Walton, Felecia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Analyses of arsenic (As) species in tissues and body fluids of individuals chronically exposed to inorganic arsenic (iAs) provide essential information about the exposure level and pattern of iAs metabolism. We have previously described an oxidation state-specific analysis of As species in biological matrices by hydride-generation atomic absorption spectrometry (HG-AAS), using cryotrapping (CT) for preconcentration and separation of arsines. To improve performance and detection limits of the method, HG and CT steps are automated and a conventional flame-in-tube atomizer replaced with a recently developed multiple microflame quartz tube atomizer (multiatomizer). In this system, arsines from AsIII-species are generated in a mixture of Tris-HCl (pH 6) and sodium borohydride. For generation of arsines from both AsIII- and AsV-species, samples are pretreated with L-cysteine. Under these conditions, dimethylthioarsinic acid, a newly described metabolite of iAs, does not interfere significantly with detection and quantification of methylated trivalent arsenicals. Analytical performance of the automated HG-CT-AAS was characterized by analyses of cultured cells and mouse tissues that contained mono- and dimethylated metabolites of iAs. The capacity to detect methylated AsIII- and AsV-species was verified, using an in vitro methylation system containing recombinant rat arsenic (+3 oxidation state) methyltransferase and cultured rat hepatocytes treated with iAs. Compared with the previous HG-CT-AAS design, detection limits for iAs and its metabolites have improved significantly with the current system, ranging from 8 to 20 pg. Recoveries of As were between 78 and 117%. The precision of the method was better than 5% for all biological matrices examined. Thus, the automated HG-CT-AAS system provides an effective and sensitive tool for analysis of all major human metabolites of iAs in complex biological matrices.
Brandans Buch der Welt – eine konkretisierte Metapher
Creators: name: Trînca, Beatrice
Publisher: name: Edition Topoi
Year: 2016

description: In der Analyse von Sankt Brandans Reise wird das literarische Potential einer religiösen Metapher untersucht, der augustinischen Metapher der Welt als Buch. Auch wenn ein signifikanter Größenunterschied zwischen Welt und Codex besteht, wird die Metapher in einigen Episoden konkret. Die Vorstellung einer Identität zwischen Welt und Buch auf der Handlungsebene und ein paradiesisches Artefakt, auf dem fast die ganze Welt täuschend echt repräsentiert ist, stehen der Erkenntnis entgegen, dass Brandans Reisetagebuch nicht die ganze Welt erfassen kann.
Comparative oxidation state specific analysis of arsenic species by high-performance liquid chromatography-inductively coupled plasma-mass spectrometry and hydride generation-cryotrapping-atomic absorption spectrometry
Creators: name: Bodnar, Wanda
name: Currier, Jenna M.
name: Matoušek, Tomáš
name: Stýblo, Miroslav
name: Ding, Lan
name: Saunders, R. Jesse
name: Cable, Peter
name: Creed, John T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The formation of methylarsonous acid (MAsIII) and dimethylarsinous acid (DMAsIII) in the course of inorganic arsenic (iAs) metabolism plays an important role in the adverse effects of chronic exposure to iAs. High-performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC-ICP-MS) and hydride generation-cryotrapping-atomic absorption spectrometry (HG-CT-AAS) have been frequently used for the analysis of MAsIII and DMAsIII in biological samples. While HG-CT-AAS has consistently detected MAsIII and DMAsIII, HPLC-ICP-MS analyses have provided inconsistent and contradictory results. This study compares the capacities of both methods to detect and quantify MAsIII and DMAsIII in an in vitro methylation system consisting of recombinant human arsenic (+3 oxidation state) methyltransferase (AS3MT), S-adenosylmethionine as a methyl donor, a non-thiol reductant tris(2-carboxyethyl)phosphine, and arsenite (iAsIII) or MAsIII as substrate. The results show that reversed-phase HPLC-ICP-MS can identify and quantify MAsIII and DMAsIII in aqueous mixtures of biologically relevant arsenical standards. However, HPLC separation of the in vitro methylation mixture resulted in significant losses of MAsIII, and particularly DMAsIII with total arsenic recoveries below 25%. Further analyses showed that MAsIII and DMAsIII bind to AS3MT or interact with other components of the methylation mixture, forming complexes that do not elute from the column. Oxidation of the mixture with H2O2 which converted trivalent arsenicals to their pentavalent analogs prior to HPLC separation increased total arsenic recoveries to ~95%. In contrast, HG-CT-AAS analysis found large quantities of methylated trivalent arsenicals in mixtures incubated with either iAsIII or MAsIII and provided high (>72%) arsenic recoveries. These data suggest that an HPLC-based analysis of biological samples can underestimate MAsIII and DMAsIII concentrations and that controlling for arsenic species recovery is essential to avoid artifacts.
Tutorial stock-flow model for tourism development
Creators: name: De Kok, Jean-Luc
Publisher: name: Zenodo
Year: 2022
Subjects: subject: System Dynamics
subject: Tourism
subject: FOS: Economics and business
subject: Feedback
subject: Dynamic
subject: VenSim
subject: MAL1

description: This tutorial model used during the kickoff meeting for the COASTAL project to demonstrate the principles of System Dynamics modelling and system feedback. More information: https://h2020-coastal.eu More information: jeanluc.dekok@vito.be The model can be opened and used in VenSim, using the free VenSim Personal Learning Edition license. https://vensim.com/free-download/
Situated Visualization in Motion for Swimming
Creators: name: Yao, Lijie
name: Bezerianos, Anastasia
name: Vuillemot, Romain
name: Isenberg, Petra
Publisher: name: arXiv
Year: 2024
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Competitive sports coverage increasingly includes information on athlete or team statistics and records. Sports video coverage has traditionally embedded representations of this data in fixed locations on the screen, but more recently also attached representations to athletes or other targets in motion. These publicly used representations so far have been rather simple and systematic investigations of the research space of embedded visualizations in motion are still missing. Here we report on our preliminary research in the domain of professional and amateur swimming. We analyzed how visualizations are currently added to the coverage of Olympics swimming competitions and then plan to derive a design space for embedded data representations for swimming competitions. We are currently conducting a crowdsourced survey to explore which kind of swimming-related data general audiences are interested in, in order to identify opportunities for additional visualizations to be added to swimming competition coverage.
Analysing the Factors Influencing Price Hike on Animal Protein-Based Food in Bangladesh: A Supply Chain Perspective
Creators: name: Sumaya Akhter
name: Sharmin Suraiya Shanta
name: Md. Rafiul Islam
name: Awishy Hasan Ayatullah
name: Md. Amanat Doulah
Publisher: name: BIHRM Supply Chain
Year: 2023

description: The increasing prices of livestock products (animal-based protein products), including meat, fish, eggs, and poultry, have become a significant concern in Bangladesh. This research is done to find out the root causes of the price hikes within the livestock products and their supply chain. The research also explores potential strategies for resolution. The study investigates key factors behind the price hike, identifies responsible parties, analyzes the overall cost of production, and proposes effective supply chain management improvements in Bangladesh. By analyzing data collected from various sources, including consumer surveys and expert opinions, the research paper highlights how factors like feed expenses, syndicates, inflation, global conflicts, and the COVID-19 pandemic greatly affect price fluctuations of livestock products.
The study emphasizes the necessity for proactive government regulations, continuous market monitoring, and strategic policies to control price hikes and reduce the adverse effects on consumers' purchasing power. Through this comprehensive analysis, the research paper aims to find out the complex entities that contribute to the price hike of livestock products (meat, eggs, poultry, fish, etc.) and provide suggestions to mitigate the adverse situation.
Visualization in Motion in Video Games for Different Types of Data
Creators: name: Bucchieri, Federica
name: Yao, Lijie
name: Isenberg, Petra
Publisher: name: arXiv
Year: 2024
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: We contribute an analysis of situated visualizations in motion in video games for different types of data, with a focus on quantitative and categorical data representations. Video games convey a lot of data to players, to help them succeed in the game. These visualizations frequently move across the screen due to camera changes or because the game elements themselves move. Our ultimate goal is to understand how motion factors affect visualization readability in video games and subsequently the players' performance in the game. We started our work by surveying the characteristics of how motion currently influences which kind of data representations in video games. We conducted a systematic review of 160 visualizations in motion in video games and extracted patterns and considerations regarding was what, and how visualizations currently exhibit motion factors in video games.
Selective hydride generation-cryotrapping-ICP-MS for arsenic speciation analysis at picogram levels: analysis of river and sea water reference materials and human bladder epithelial cells
Creators: name: Ishida, María C.
name: Trojánková, Nikola
name: Currier, Jenna M.
name: Mester, Zoltán
name: Saunders, R. Jesse
name: Dědina, Jiří
name: Matoušek, Tomáš
name: Musil, Stanislav
name: González-Horta, Carmen
name: Stýblo, Miroslav
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: An ultra sensitive method for arsenic (As) speciation analysis based on selective hydride generation (HG) with preconcentration by cryotrapping (CT) and inductively coupled plasma- mass spectrometry (ICP-MS) detection is presented. Determination of valence of the As species is performed by selective HG without prereduction (trivalent species only) or with L-cysteine prereduction (sum of tri- and pentavalent species). Methylated species are resolved on the basis of thermal desorption of formed methyl substituted arsines after collection at −196°C. Limits of detection of 3.4, 0.04, 0.14 and 0.10 pg mL−1 (ppt) were achieved for inorganic As, mono-, di- and trimethylated species, respectively, from a 500 μL sample.
In Other Words: George Herbert’s Metaphorical Textures
Creators: name: Lobsien, Verena Olejniczak
Publisher: name: Edition Topoi
Year: 2016

description: Der Aufsatz untersucht Struktur und Funktion der konzeptuellen Metapher (conceit) in der metaphysischen Dichtung des 17. Jahrhunderts. Am Beispiel zweier Gedichte von George Herbert, „Love (3)“ und „Easter Wings“, wird gezeigt, wie poetische Texte mit ihrer äußersten, paradoxen Herausforderung umgehen: „mit anderen Worten“ das zu sagen, was sich als Verborgenes und Transzendentes der sprachlichen Verfügung, zugleich jeder räumlichen Repräsentation entzieht.
Coronary sinus reducer in an aneurysmatic coronary sinus: angina relief in challenging anatomies?
Creators: name: Kyriakoulis, Konstantinos G.
name: Dimitriadis, Kyriakos
name: Pyrpyris, Nikolaos
name: Iliakis, Panagiotis
name: Aznaouridis, Konstantinos
name: Giannini, Francesco
name: Tsioufis, Konstantinos
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Coronary sinus reducer in an aneurysmatic coronary sinus: angina relief in challenging anatomies?
Introduction: Space and Metaphor
Creators: name: Horn, Fabian
Publisher: name: Edition Topoi
Year: 2016

description: Die Einleitung des Tagungsbands Spatial Metaphors: Ancient Texts and Transformations umfasst zwei Abschnitte: Der erste Teil enthält vorbereitende Anmerkungen zur Metapherntheorie und versucht, durch die Klassifizierung anhand der Kriterien von Spezifität (specificity) und Umfang (extent) eine theoretische Struktur für die Untersuchung von Raummetaphern zu erarbeiten. Der Zugang, der dieser Typologie zugrundeliegt, steht in der Tradition der Theorie konzeptueller Metaphern von Lakoff und Johnson. Der zweite Abschnitt bietet eine kurze Übersicht und Zusammenfassung der einzelnen Beiträge des Bands (von denen nicht alle auf die Theorie konzeptueller Metaphern zurückgreifen) mit besonderer Berücksichtigung der Fragestellung, wie sich die untersuchten Metaphern zu der eingangs vorgestellten Struktur verhalten. Dabei wird deutlich, dass, obgleich die Möglichkeit einer formalen Klassifikation von Raummetaphern besteht, jede philologische Untersuchung und Interpretation immer die entsprechenden Kontexte miteinbeziehen muss und dabei nicht von abstrakten theoretischen Metaphermodellen, sondern den Texten selbst ihren Ausgang nehmen muss.
Presentazione
Creators: name: Lupinu, Giovanni
Publisher: name: Bollettino di Studi Sardi
Year: 2016

description: Questo numero del Bollettino di Studi Sardi si apre nel ricordo triste di due amici. Il primo, scomparso il 4 giugno 2016, è Nicola Tanda, a lungo componente del Comitato scientifico della nostra rivista. Lo spessore dei suoi lavori di letteratura italiana e l’apporto decisivo che ha offerto per la valorizzazione critica della cultura sarda saranno certamente posti in risalto dagli studi che con la sua opera dovranno fare i conti. Qui, però, ci è caro ricordarne l’umanità complessa, lo sguardo pensieroso e dolente, rivelatore di quell’intelligenza arguta che dispensava con generosità. Il secondo amico che ricordiamo con affetto e rimpianto, mancato il 25 giugno 2016, è Tomasino Pinna, storico delle religioni autore di solidi contributi, anche sulle pagine del BSS, capaci di gettare luce, con rigore di metodo, su importanti vicende del nostro passato. Chi ha avuto la possibilità di conoscerlo porterà il ricordo, oltreché di uno studioso severo ed esigente con sé stesso, di un uomo di convinzioni etiche cristalline, capace di lasciare col sorriso e con sobrietà una lezione importante di coerenza.
description: Bollettino di Studi Sardi, V. 9 (2016)
In Vivo Versus In Vitro Airway Surface Liquid Nicotine Levels Following Cigarette Smoke Exposure
Creators: name: Alexis, N.
name: Tarran, R.
name: Bridges, A.
name: Clunes, L. A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Whole cigarette smoke (WCS) is composed of approximately 5% particulates and 95% vapors by weight and is difficult to reproduce quantitatively in the laboratory, where typically, routine in vitro application of smoke normally only utilizes the particulate phase. In this study, we used a system for exposing epithelial cells cultured at an air-liquid interface to WCS. We hypothesized that the use of WSC in vitro was more relevant to what is seen in vivo than methods of cigarette smoke application that only use a small fraction of WCS [i.e., aqueous extract or cigarette smoke condensate (CSC)]. To test this hypothesis, we compared nicotine and cotinine concentrations (measured by mass spectrometry) in the airway surface liquid (ASL) of human primary bronchial epithelial cultures (HBECs) exposed to serial dilutions of WCS to the concentrations found in induced sputum of human subjects who had recently smoked a cigarette; this was also compared to the concentrations found after an exposure to a concentration of CSC commonly used in vitro. When measured by mass spectrometry, nicotine levels were not significantly different in induced sputum versus the ASL of HBECs exposed in vitro to a 1:30 exposure of WCS. However, HBECs that had been exposed to CSC returned significantly lower concentrations of ASL nicotine. These results suggest that nicotine is a good dosimetry marker of WCS exposure and provides direct evidence that the use of WCS is more relevant than the use of CSC for in vitro systems.
Metaphors as Models of Thinking
Creators: name: Raible, Wolfgang
Publisher: name: Edition Topoi
Year: 2016

description: Unsere kognitive Fähigkeit, die Welt um uns zu interpretieren, beruht weitgehend auf Metapher und Metonymie. Beide erlauben es uns, ausgehend von den Prinzipien von Ähnlichkeit und Kontiguität zwischen Konzepten, Beziehungen zwischen Unbekanntem und Bekanntem, Entlegenem und Naheliegendem, Unsichtbarem und Sichtbarem zu sehen. Die Atomisten schufen solch eine Ähnlichkeit oder Analogie zwischen der sichtbaren griechischen Schrift und der unsichtbaren Welt der Atome. Zeitgenössische Biologen nutzen dieses Denkmodell weiterhin in Bezug auf molekulare Biologie. Durch vielfältige Beispiele von der Bibelexegese bis zur Welt der Naturwissenschaft und Technik wird die weite Verbreitung solcher Denkmodelle (und teilweise auch ihre Zeitgebundenheit) aufgezeigt. In der Vergangenheit bestand ein großes Problem in der Hauptströmung europäischen Denkens, die auf Beziehungen zwischen Wörten statt zwischen Konzepten, wie im Fall der Metapher, beharrte.
Spatial Metaphors as Rhetorical Figures. Case Studies from Wisdom Texts of the Egyptian New Kingdom
Creators: name: Biase-Dyson, Camilla Di
Publisher: name: Edition Topoi
Year: 2016

description: Diese Studie analysiert einige Weisheitstexte aus dem ägyptischen Neuen Reich und der Dritten Zwischenzeit (1550–712 BC), um die rhetorische sowie kommunikative Anwendungen von räumlichen Metaphern zu skizzieren. Unser Verständnis altägyptischer Rhetorik wird dadurch verstärkt: Wir sehen, zum Beispiel, dass die räumlichen Metaphern (insbesondere die Wegmetaphern) sich vermehren und expliziter werden wobei die rhetorische Qualität des Textes ebenso zunimmt – oder anders ausgedrückt, dass die enumerative Weisheitsgattung zunehmend von den Aufrufen der Schultexte beeinflusst wird.
KRATĒR. The Mixing-Vessel as Metaphorical Space in Ancient Greek Tradition
Creators: name: Schlesier, Renate
Publisher: name: Edition Topoi
Year: 2016

description: Aristoteles konzipierte das Substantiv metaphora (wörtlich „Transfer“) als das Ergebnis eines sprachlichen und kognitiven Übertragungsprozesses, der einen Vergleich oder eine Analogie zwischen zwei materiellen oder geistigen Elementen voraussetzt. Dieser Metapherbegriff erlaubt jedoch nicht, die Auswirkung von semantischen Mischungen solcher Elemente zu erfassen. Dies zeigt der Begriff kratēr (wörtlich „Misch-Objekt“) in der griechischen Dichtung, wo er als Emblem und nicht notwendigerweise als Metapher für verschiedene Formen räumlicher und nicht-räumlicher Übertragung gebraucht wird, aber auch für Mischungen, die im Symposion stattfinden.
L’informatica al servizio della filologia e della linguistica sarda: il corpus ATLiSOr (Archivio Testuale della Lingua Sarda delle Origini)
Creators: name: Fortunato, Maria
name: Ravani, Sara
Publisher: name: Bollettino di Studi Sardi
Year: 2015

description: Bollettino di Studi Sardi, V. 8 (2015)
Metaphor and Spatial Conceptualization. Observations on Orientational Metaphors in Lycophron’s Alexandra
Creators: name: Horn, Fabian
Publisher: name: Edition Topoi
Year: 2016

description: In Bezugnahme auf die theoretischen und methodischen Ansätze der kognitionswissenschaftlichen Theorie konzeptueller Metaphern und auf der Grundlage des Texts von Lykophrons Alexandra zeigt dieser Beitrag die Existenz der konzeptuellen Orientierungsmetaphern AKTIV IST OBEN (zusammen mit der korrespondierenden entgegengesetzten Vorstellung PASSIV/ZERSTÖRT/TOT IST UNTEN) auf. Zahlreiche einzelne textuelle Belege diese Vorstellung erscheinen in der Alexandra, oftmals in der Form von Präpositionen und Präfixen (ἀνά/ἀνα-, ἐπί/ἐπι-; κατά/κατα-) aber auch im Falle von Vokabeln, deren Grundbedeutung die Richtungsbestimmung oben oder unten enthält, wie αἴρω, dessen metaphorische Verwendung in der Alexandra (Lyc. 1228, 1295) ausführlich diskutiert wird.
Eyes on the Phish(er): Towards Understanding Users' Email Processing Pattern and Mental Models in Phishing Detection
Creators: name: Zhuo, Sijie
name: Biddle, Robert
name: Recomendable, Jared Daniel
name: Russello, Giovanni
name: Lottridge, Danielle
Publisher: name: arXiv
Year: 2024
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Phishing emails typically masquerade themselves as reputable identities to trick people into providing sensitive information and credentials. Despite advancements in cybersecurity, attackers continuously adapt, posing ongoing threats to individuals and organisations. While email users are the last line of defence, they are not always well-prepared to detect phishing emails. This study examines how workload affects susceptibility to phishing, using eye-tracking technology to observe participants' reading patterns and interactions with tailored phishing emails. Incorporating both quantitative and qualitative analysis, we investigate users' attention to two phishing indicators, email sender and hyperlink URLs, and their reasons for assessing the trustworthiness of emails and falling for phishing emails. Our results provide concrete evidence that attention to the email sender can reduce phishing susceptibility. While we found no evidence that attention to the actual URL in the browser influences phishing detection, attention to the text masking links can increase phishing susceptibility. We also highlight how email relevance, familiarity, and visual presentation impact first impressions of email trustworthiness and phishing susceptibility.
description: 25 pages, 6 figures, currently accepted in EuroUsec2024, but not yet published
Sustainable Agricultural Supply Chain Management in the Chittagong Hill Tracts:  A Roadmap Towards Development
Creators: name: Md. Sanadiule Shorif Ullash
name: , Rawnak Labiba Noor
name: Quazi Monjur E-Elahi
name: Hridi Juberi
Publisher: name: BIHRM Supply Chain
Year: 2023

description: The Chittagong Hill Tracts (CHT) of Bangladesh have demonstrated strong agricultural potential through diversifying crops, however difficulties impede the region's agricultural supply chain growth. This study presents a long-term framework for CHT agricultural expansion that is sustainable. The study begins by outlining the historical constraints of the CHT's agricultural economy, which was characterized by subsistence farming and intermediaries' domination. Recent infrastructural upgrades, such as new roads, have created new prospects for growing profitable crops such as fruits and spices. However, transportation continues to be a major barrier, hindering effective supply chain management and market access.
To maximize the potential of the agriculture business in the CHT, a sustainable supply chain management structure based on sustainability, efficiency, and traceability principles is recommended. Manufacturing, storage, transportation, packaging, marketing, and information sharing are among the sectors identified as needing improvement in the research. The study incorporates quantitative and qualitative data gathered from 50 farmers via questionnaires and interviews. Low agricultural yields, post-harvest losses, insufficient storage facilities, expensive transportation, crop damage during transit and storage, restricted market prospects, and poor information exchange are all highlighted.
The suggested roadmap tackles these issues by encouraging better farming practices, improved storage facilities, efficient transportation networks, suitable packaging, expanded marketing options, and improved information flow. Implementing this approach would result in a more efficient, profitable, and environmentally sustainable agricultural supply chain in the CHT, which would benefit farmers, consumers, and the area as a whole. Collaboration among the local community, government, and commercial sector will be critical for the region's effective implementation and overall growth.
Spatial Metaphor in the Pauline Epistles
Creators: name: Egg, Markus
Publisher: name: Edition Topoi
Year: 2016

description: Dieser Beitrag analysiert räumliche Metaphern in den Paulusbriefen im Rahmen der kognitiven Metapherntheorie Lakoffs und Johnsons. Diese Theorie modelliert Metaphern als Zugriff auf einen komplexeren Sinnbereich (‚Zieldomäne‘), indem man die Struktur eines einfacheren Sinnbereichs (‚Quelldomäne‘) auf die Zieldomäne abbildet. Paulus’ Metaphern sind innovativ, doch ihr Hauptmerkmal ist Verfremdung, die eine neue Perspektive auf vertraute Phänomene eröffnet. Für Metaphern bedeutet dies, dass ihre Grenzen hervorgehoben werden. Aber wenn Metaphern ein komplexes Konzept zugänglicher machen, erscheint Verfremdung für die didaktischen und ermahnenden Briefe unpassend. Zudem sind die Themen des Paulus neuartig und bedürfen keiner Verfremdung, um Vertrautheit zu überwinden. Ich führe Paulus’ Motivation für die Verwendung verfremdender Metaphern auf die Neuartigkeit seiner Gedanken zurück. Um diese ausdrücken zu können, musste er Metaphern verwenden, die nicht vollkommen präzise sind. Daher verfremdete er diese, um ihre Beschränkungen aufzuzeigen und davor zu warnen, sie zu weit zu treiben. Folglich kann Verfremdung nicht nur zur Aufhebung von Vertrautheit eingesetzt werden.
Tendon cells in vivo form a three dimensional network of cell processes linked by gap junctions.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Tendons respond to mechanical load by modifying their extracellular matrix. The cells therefore sense mechanical load and coordinate an appropriate response to it. We show that tendon cells have the potential to communicate with one another via cell processes and gap junctions and thus could use direct cell/cell communication to detect and/or coordinate their load responses. Unfixed cryosections of adult rat digital flexor tendons were stained with the fluorescent membrane dye DiI to demonstrate cell shape. Similar sections were immunolabelled with monoclonal antibodies to rat connexin 32 or connexin 43 to demonstrate gap junctions and counterstained with propidium iodide to show nuclei, or the membrane stain DiOC7 to show cell membranes. Sections were examined with a laser scanning confocal microscope and 3-dimensional reconstructions were prepared from optical section series to demonstrate cell shape and the position of connexin immunolabel. Cells had a complex interconnected morphology with gap junctions at points of contact with other cells. Cell bodies contained the nucleus and extended broad flat lateral cell processes that enclosed collagen bundles and interacted with similar processes from adjacent cells. They also had long thin longitudinal processes interacting with the cell process network further along the tendon. Connexin 43 occurred where cell processes met and between cell bodies, whereas connexin 32 was only found between cell bodies. The results indicate the presence of a 3-dimensional communicating network of cell processes within tendons. The intimate relationship between cell processes and collagen fibril bundles suggests that the cell process network could be involved in load sensing and coordination of response to load. The presence of 2 different types of connexins suggests that there could be at least 2 distinct communicating networks.
Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages: Biliary tree stem cell niche
Creators: name: Rossi, Massimo
name: Semeraro, Rossella
name: Gaudio, Eugenio
name: Onori, Paolo
name: Berloco, Pasquale Bartolomeo
name: Wang, Yunfang
name: Carpino, Guido
name: Cardinale, Vincenzo
name: Reid, Lola M.
name: Anceschi, Maurizio
name: Alvaro, Domenico
name: Brunelli, Roberto
name: Franchitto, Antonio
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Stem/progenitors have been identified intrahepatically in the canals of Hering and extrahepatically in glands of the biliary tree. Glands of the biliary tree (peribiliary glands) are tubulo-alveolar glands with mucinous and serous acini, located deep within intrahepatic and extrahepatic bile ducts. We have shown that biliary tree stem/progenitors (BTSCs) are multipotent, giving rise in vitro and in vivo to hepatocytes, cholangiocytes or pancreatic islets. Cells with the phenotype of BTSCs are located at the bottom of the peribiliary glands near the fibromuscular layer. They are phenotypically heterogeneous, expressing transcription factors as well as surface and cytoplasmic markers for stem/progenitors of liver (e.g. SOX9/17), pancreas (e.g. PDX1) and endoderm (e.g. SOX17, EpCAM, NCAM, CXCR4, Lgr5, OCT4) but not for mature markers (e.g. albumin, secretin receptor or insulin). Subpopulations co-expressing liver and pancreatic markers (e.g. PDX1+/SOX17+) are EpCAM+/−, and are assumed to be the most primitive of the BTSC subpopulations. Their descendants undergo a maturational lineage process from the interior to the surface of ducts and vary in the mature cells generated: pancreatic cells in hepatopancreatic ducts, liver cells in large intrahepatic bile ducts, and bile duct cells along most of the biliary tree. We hypothesize that there is ongoing organogenesis throughout life, with BTSCs giving rise to hepatic stem cells in the canals of Hering and to committed progenitors within the pancreas. The BTSCs are likely to be central to normal tissue turnover and injury repair and to be key elements in the pathophysiology of liver, pancreas and biliary tree diseases, including oncogenesis.
Histone Demethylase JHDM2A Is Involved in Male Infertility and Obesity
Creators: name: Tateishi, K.
name: Zhang, Y.
name: Okada, Y.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Recent studies indicate that histone lysine methylation is subject to enzyme-catalyzed reversion, and jumonji C (JmjC) domain–containing proteins have been identified as one of the members of histone demethylases. Although an increasing number of histone demethylases have been identified and biochemically characterized, their biological functions are poorly characterized. To elucidate the physiological functions, we generated the knockout mouse model of dimethylated or monomethylated histone 3 lysine 9 (H3K9me2/1)–specific JmjC domain–containing histone demethylase 2A (JHDM2A; also known as JMJD1A and KDM3A) and showed that JHDM2A is essential for spermatogenesis. Jhdm2a-deficient mice exhibited impaired postmeiotic chromatin condensation, which caused infertility, even though the hormonal levels were maintained. Further molecular and biochemical analysis revealed that JHDM2A directly bound to the core promoter regions of transition nuclear protein 1 (Tnp1) and protamine 1 (Prm1) genes, and it induced the transcriptional activation of these genes by removing H3K9 methylation, which is known as a silencing marker of gene transcription. This work uncovered a role for JHDM2A in spermatogenesis and identified 2 downstream genes that are critical for sperm nuclear condensation. In addition, we also showed that JHDM2A plays a role in regulating fat metabolic gene expression in muscle and brown fat tissue, and the knockout mice exhibited obesity and hyperlipidemia. Thus, JHDM2A possesses organ/tissue-specific target genes, and impairment of this molecule cannot be compensated by other JmjC-containing histone demethylases, suggesting the importance of this molecule in vivo.
Taufe als räumliche Metapher in den Briefen des Paulus
Creators: name: Cilliers Breytenbach
Publisher: name: Edition Topoi
Year: 2016

description: Der vorliegende Aufsatz untersucht das paulinische Verständnis der Taufe als räumliche Metapher. Vor dem Hintergrund des Gebrauchs von βάπτειν/βαπτίζειν im Altgriechischen wird offensichtlich, dass Paulus den Begriff auf spezifische metaphorische Weise verwendet. Paulinische Formulierungen, wie „in den Leib Christi eingetaucht werden“ (1 Kor 12,13), „in Christus eingetaucht werden“ (Gal 3,28) und „in den Tod Christi eingetaucht werden“ (Rom 6,3–5) werden untersucht und deren Implikationen im Rückgriff auf aktuelle metaphertheoretische Ansätze diskutiert.
Irdisches Himmelreich. Die ‚Stiftshütte‘ (Ex 25–40*) als theologische Metapher
Creators: name: Utzschneider, Helmut
Publisher: name: Edition Topoi
Year: 2016

description: Die biblische Erzählung von der Errichtung des Sinaiheiligtums, der sogenannten Stiftshütte, im Buch Exodus Kap 25–40 wird als „ausgeführte Metapher“ im Sinne Paul Ricoeurs sowie als „absolute Metapher“ im Sinne Hans Blumenbergs gedeutet. Das heilige Zelt und seine sakrale Ausstattung, das die Israeliten auf Anweisung Gottes an Mose herzustellen haben, soll Gott als ‚Wohnung‘ bei den Israeliten dienen. Der Raum und die Räume des Heiligtums werden aus unterschiedlichen Perspektiven entwickelt. Der metaphorische Charakter der Erzählung erweist sich dadurch, dass das ‚Wohnen Gottes‘ nur in Spannung zwischen göttlichem und menschlichem Bereich dargestellt werden kann. Der Raum des Heiligtums vereinigt gegensätzliche und zugleich komplementäre Weisen der Präsenz Gottes unter den Menschen.