cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Dark Mimesis : a cultural history of the scalping paradigm
Creators: name: Peotto, Thomas
Publisher: name: University of British Columbia
Year: 2018

description: This thesis examines the history of scalp bounties, i.e., the payment of money or trade goods in wartime to volunteers, militias, and mercenaries, for the scalps of indigenous North Americans in the British North American colonies and the post-Revolutionary United States, from the mid-1630s to the end of the 19th century. Out of a general Euro-American colonial backdrop of military alliances with indigenous peoples against indigenous third parties and rival European colonies, and the offering of bounties for captives and proofs of death to indigenous and European volunteers, British colonists parted ways with other Europeans by grafting a specific request for scalps, per eastern North American practice, with a broader policy of ethnic cleansing against indigenous peoples, and the outsourcing of this work to frontier populations with a vested interest in seizing indigenous land and resources. Synthesizing and surveying primary and secondary sources, I argue that Euro-American scalp bounties and the pursuit of those bounties, popularly known as scalp-hunting, were informed by 16th-century designations of indigenous Americans as illegitimate combatants, cross-cultural misreadings of indigenous warfare as a primordial or dysfunctional version of Europeans’, and a broader context of genocidal intent towards indigenous peoples collectively. Imagining themselves as the potential victims of Indian uprisings, Anglo-Americans invoked scalping to metonymize nightmare images of indigenous warriors as merciless and cruel; in turn, scalping was invoked to justify vigilante killings, pre-emptive violence, slave trading, and scorched earth campaigns of extirpation. Whites scalping Indians, on the other hand, was imagined as historically inevitable, and portrayed in art and culture as exemplifying their inheritance and supersession of indigenous lands, resources, and ‘American’ identity. I argue that scalp bounties among Anglo-Americans, and their justification as historically inevitable, is best understood as mimetic re-enactment of the dehumanizing stereotypes which rendered indigenous peoples as illegitimate combatants and the negative mirror image of Euro-American settlers. I refer to this bundle of ideas, truisms, stock images and narratives as “the scalping paradigm.”
CBS News Poll: Trump/Charlottesville/North Korea
Creators: name: CBS News
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: North Korea's nuclear program (1); U.S. military action against North Korea (2); Donald Trump's response to the events in Charlottesville, Virginia (4); Trump handling issues on race and race relations (2); registered to vote (1); vote in the 2016 presidential election (1); personal finances (1); political party preference (2).
title: Life strategies of microorganisms in the environment and in host organisms: Leopoldina Symposium
Creators: name: :None
Publisher: name: Wissenschaftliche Verlagsgesellschaft Stuttgart
Year: 2008
Subjects: subject: Mikroorganismus
subject: Ökologie
subject: Mikrobiologie
subject: 570

description: Viele Prokaryoten (Bakterien wie Archaeen) in Wasser, Boden oder Wirtsorganismus zeigen häufig spezifische, hoch entwickelte Anpassungen zur Nutzung des umgebenden Milieus als Energie- und Nährstoffquelle sowie als Überlebensraum. Bei prokaryotischen Organismen spielen sich die Anpassungen an die abiotische oder biotische Umgebung fast nur auf der Ebene des Stoffwechsels und der molekularen bzw. makromolekularen Strukturen und Wechselwirkungen ab. Auf dieser Ebene zeigen sich tatsächlich typisch prokaryotische Leistungen: eine Nutzung „ungewöhnlicher“ Energiequellen, grundlegende Syntheseleistungen, enzymatische Katalysen, Anpassungen an extreme Verhältnisse, wie hohe Temperaturen, Kolonisations- und Invasionsmechanismen, und Regulationsvorgänge. Der Band behandelt die Rolle von Mikroorganismen in den globalen Elementkreisläufen, wie z. B. dem Schwefelstoffwechsel, dem Methanstoffwechsel, der Kohlendioxidfixierung oder der Ammoniakoxidation, Symbiosen mit Bakterien-Eukaryoten-Interaktionen auf der Grundlage von Schwefel- oder Stickstoffstoffwechsel, Modelle zum prokaryotischen Ursprung von Organellen in Eukaryoten sowie die Beteiligung von Mikroorganismen an Infektions- und Pathogenitätsvorgängen.
description: Nova Acta Leopoldina: NAL ; Abhandlungen der Deutschen Akademie der Naturforscher Leopoldina, vol. 96, Nummer 356
Anomalous integer quantum Hall effect in AA-stacked bilayer graphene
Creators: name: Hsu, Ya-Fen
name: Guo, Guang-Yu
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Recent experiments indicate that AA-stacked bilayer graphenes (BLG) could exist. Since the energy bands of the AA-stacked BLG are different from both the monolayer and AB-stacked bilayer graphenes, different integer quantum Hall effect in the AA-stacked graphene is expected. We have thus calculated the quantized Hall conductivity $σ_{xy}$ and also longitudinal conductivity $σ_{xx}$ of the AA-stacked BLG within the linear response Kubo formalism. Interestingly, we find that the AA-stacked BLG could exhibit both conventional insulating behavior (the $\barν=0$ plateau) and chirality for $|\barμ|
description: submitted to Physical Review B
Design, characterization and in vivo evaluation of nanostructured lipid carriers (NLC) as a new drug delivery system for hydrochlorothiazide oral administration in pediatric therapy
Creators: name: Cirri, Marzia
name: Maestrini, Lavinia
name: Maestrelli, Francesca
name: Mennini, Natascia
name: Mura, Paola
name: Ghelardini, Carla
name: Di Cesare Mannelli, Lorenzo
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The hydrochlorothiazide (HCT) low solubility and permeability give rise to limited and variable bioavailability; its low stability makes it difficult to develop stable aqueous liquid formulations; its low dose makes the achievement of a homogeneous drug distribution very difficult. Thus, the aim of this study was to investigate the effectiveness of a strategy based on the development of nanostructured lipid carriers (NLC) as an innovative oral pediatric formulation of HCT with improved therapeutic efficacy. The performance of various synthetic and natural liquid lipids was examined and two different preparation methods were employed, i.e. homogenization-ultrasonication (HU) and microemulsion (ME), in order to evaluate their influence on the NLC properties in terms of size, polydispersity index, ζ-potential, entrapment efficiency, gastric stability, and drug release properties. Precirol®ATO5 was used as solid lipid and Tween®80 and Pluronic®F68 as surfactants, formerly selected in a previous study focused on the development of HCT-solid lipid nanoparticles (SLNs). The presence of Pluronic®F68 did not allow ME formation. On the contrary, using Tween®80, the ME method enabled a higher entrapment efficiency than the HU. Regardless of the preparation method, NLCs exhibited great entrapment efficiency values clearly higher than previous SLNs. Moreover, NLC-ME formulations provided a prolonged release, which lasted for 6 h. In particular, NLC-ME containing Tween®20 as Co-Surfactant showed the best performances, giving rise to a complete drug release, never achieved with previous SLN formulations, despite their successful results. In vivo studies on rats confirmed these results, displaying their best diuretic profile. Moreover, all HCT-loaded NLC formulations showed higher stability than the corresponding SLNs.
D 2.15 Workshop Report 2
Creators: name: Austen, Kat
Publisher: name: Zenodo
Year: 2022

description: This report gives an overview of the execution and outcomes of workshops carried out during the ACTION project up to and including the second round of the ACTION Accelerator. It is intended to be of use to ACTION consortium, researchers and practitioners working with the Accelerator model, and those with an interest in running citizen science projects. The report details activities since the Round 1 kick-off meeting until the project end. The report includes the outcomes of bespoke co-design workshops with ACTION Case Study citizen science projects, the ACTION Round 2 Kick-Off meeting, Diversity and Inclusion workshops in Round 1 and Round 2, and webinars. It is expected that the structure of the Kick-Off meeting and some of the associated materials will be of use to citizen science practitioners and those conceiving of citizen science projects.
Nasal delivery of H5N1 avian influenza vaccine formulated with GenJet™ or in vivo-jetPEI® induces enhanced serological, cellular and protective immune responses
Creators: name: Cao, Weiping
name: Mishina, Margarita
name: Amoah, Samuel
name: Mboko, Wadzanai P.
name: Bohannon, Caitlin
name: McCoy, James
name: Mittal, Suresh K.
name: Gangappa, Shivaprakash
name: Sambhara, Suryaprakash
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Avian influenza virus infection is a serious public health threat and preventive vaccination is the most cost-effective public health intervention strategy. Unfortunately, currently available unadjuvanted avian influenza vaccines are poorly immunogenic and alternative vaccine formulations and delivery strategies are in urgent need to reduce the high risk of avian influenza pandemics. Cationic polymers have been widely used as vectors for gene delivery in vitro and in vivo. In this study, we formulated H5N1 influenza vaccines with GenJet™ or in vivo-jetPEI®, and showed that these formulations significantly enhanced the immunogenicity of H5N1 vaccines and conferred protective immunity in a mouse model. Detailed analyses of adaptive immune responses revealed that both formulations induced mixed TH1/TH2 antigen-specific CD4 T-cell responses, antigen-specific cytotoxic CD8 T-cell and memory B-cell responses. Our findings suggest that cationic polymers merit future development as potential adjuvants for mucosal delivery of poorly immunogenic vaccines.
Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer
Creators: name: Kim, Ga Hee
name: Won, Ji Eun
name: Byeon, Yeongseon
name: Kim, Min Gi
name: Wi, Tae In
name: Lee, Jae Myeong
name: Park, Yun-Yong
name: Lee, Jeong-Won
name: Kang, Tae Heung
name: Jung, In Duk
name: Shin, Byung Cheol
name: Ahn, Hyung Jun
name: Lee, Young Joo
name: Sood, Anil K.
name: Han, Hee Dong
name: Park, Yeong-Min
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Angiogenesis plays an essential role in the growth and metastasis of tumor cells, and the modulation of angiogenesis can be an effective approach for cancer therapy. We focused on silencing the angiogenic gene PLXDC1 as an important factor for anti-angiogenesis tumor therapy. Herein, we developed PLXDC1 small interfering siRNA (siRNA)-incorporated chitosan nanoparticle (CH-NP/siRNA) coated with hyaluronic acid (HA) to target the CD44 receptor on tumor endothelial cells. This study aimed to improve targeted delivery and enhance therapeutic efficacy for tumor anti-angiogenesis. The HA-CH-NP/siRNA was 200 ± 10 nm in size with a zeta potential of 26.4 mV. The loading efficiency of siRNA to the HA-CH-NP/siRNA was up to 60%. The selective binding of HA-CH-NP/siRNA to CD44-positive tumor endothelial cells increased by 2.1-fold compared with that of the CD44 nontargeted CH-NP/siRNA. PLXDC1 silencing by the HA-CH-NP/siRNA significantly inhibited tumor growth in A2780 tumor-bearing mice compared with that in the control group (p p p p
Microwave sensor based on molecularly imprinted silica for the detection of phenylacetaldehyde in wine
Creators: name: Bou-Maroun, Élias
name: Rossignol, Jérôme
name: Stuerga, Didier
name: Cayot, Philippe
name: Gougeon, Régis D.
Publisher: name: Zenodo
Year: 2022
Subjects: molecularly imprinted silica
microwave sensor
wine oxidation
phenylacetaldehyde
fast analysis

description: In this work, a microwave sensor having a molecularly imprinted silica (MIS) as sensitive material was developed to detect phenylacetaldehyde (PAA), a chemical indicator of wine oxidation. This real time method does not require any sample preparation and represents an alternative to expensive and tedious chromatographic methods. The methodology used to achieve this goal begins with the synthesis of several imprinted and non-imprinted silica (NIS). These MIS and NIS have been tested on their ability to extract PAA from hydro alcoholic medium and finally their selectivity toward PAA in the presence of competing molecules. The selected MIS was deposited on the surface of a microwave antenna and was used to detect PAA in red wine. The detection limit of the sensor is near the μg.L-1 level below the off-flavour threshold of PAA.
Simulated spectral states of AGN and observational predictions
Creators: name: Sobolewska, M. A.
name: Siemiginowska, A.
name: Gierlinski, M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Active galactic nuclei (AGN) and galactic black hole binaries (GBHs) represent two classes of accreting black holes. They both contain an accretion disc emitting a thermal radiation, and a non-thermal X-ray emitting corona. GBHs exhibit state transitions, and their spectral states are characterized by different luminosity levels and shapes of the spectral energy distribution (SED). If AGN transitioned in a similar way, the characteristic timescales of such transitions would exceed ~10^5 years. Thus, the probability to observe an individual AGN transiting between different spectral states is very low. In this paper we follow a spectral evolution of a GBH, GRO~J1655-40, and then apply its SED evolution pattern to a simulated population of AGN under an assumption that a large sample of AGN should contain a mixture of sources in different spectral states. We model the X-ray spectra of GRO J1655-40 with the eqpair model and then scale the best-fitting models with the black hole mass to simulate the AGN spectra. We compare the simulated and observed AGN SEDs to determine the spectral states of observed Type 1 AGN, LINER and NLS1 populations. We conclude that bright Type 1 AGN and NLS1 galaxies are in a spectral state similar to the soft spectral state of GBHs, while the spectral state of LINERs may correspond to the hard spectral state of GBHs. We find that taking into account a spread in the black hole masses over several orders of magnitude, as in the observed AGN samples, leads to a correlation between the X-ray loudness and the monochromatic luminosity at 2500A, similar to that found in observations. We predict however that the correlation changes its sign around a critical luminosity of L_crit ~ 0.01 L_E.
description: 11 pages, 6 figures, MNRAS, in press
Enabling practical deployment of silicon ring resonator-based systems
Creators: name: Jayatilleka, Hasitha
Publisher: name: University of British Columbia
Year: 2019

description: Microring resonators (MRRs) on silicon photonic platforms allow for low-power, dense, and large-scale manipulation of optical signals on-chip. MRR-based modulators, switches, and filters have become key building blocks in integrated optical circuits for applications in future data communications, high-performance computing, and sensing. This thesis presents solutions for overcoming several challenges towards practical deployment of MRR systems. The performance of MRR is highly susceptible to temperature and fabrication variations, which cause significant shifts in the MRR's spectral responses. In-resonator photoconductive heaters (IRPHs), formed by doping MRRs’ waveguides show high responsivities. As IRPHs do not require additional material depositions, photodetectors, or power taps and use the same contact pads for both sense and tune operations, they can be used to automatically tune and temperature stabilize MRRs without compromising the cost or area of the devices. Automatic tuning and stabilization of one- and two-ring filters are demonstrated. Multi-ring filters offer attractive spectral features such as wide pass-bands, steep roll-offs, and large extinction ratios. Using IRPHS, automatic tuning of a four-ring Vernier ring filter across a record 37.6 nm wavelength and wavelength locking to account for a record 65 degrees temperature variation is demonstrated. A tuning algorithm in which the number of iterations scales linearly with the number of coupled rings in the system is presented. As this method typically does not rely on the output spectral shape of the filter, it is applicable to a wider range of coupled resonator systems. Application of this tuning method is then demonstrated for various multi-ring filters by both simulation and experiment. Crosstalk can be a major source of signal degradation in large-scale MRR systems. Interchannel and intrachannel crosstalk of one- and two-ring MRR filters are experimentally investigated. The power penalties due to interchannel crosstalk are presented as functions of channel spacing and adjacent channel isolation. Intrachannel crosstalk of one-ring, cascaded, and series-coupled add-drop filters are compared and spectral conditions that will ensure low intrachannel crosstalk is presented. MRR filters with extremely small radii of 2.75 um, large free spectral ranges of 34.3 nm, and high thermal tuning efficiencies of 2.78 nm/mW are presented.
Charge transport through single molecules, quantum dots, and quantum wires
Creators: name: Andergassen, S.
name: Meden, V.
name: Schoeller, H.
name: Splettstoesser, J.
name: Wegewijs, M. R.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We review recent progresses in the theoretical description of correlation and quantum fluctuation phenomena in charge transport through single molecules, quantum dots, and quantum wires. A variety of physical phenomena is addressed, relating to co-tunneling, pair-tunneling, adiabatic quantum pumping, charge and spin fluctuations, and inhomogeneous Luttinger liquids. We review theoretical many-body methods to treat correlation effects, quantum fluctuations, nonequilibrium physics, and the time evolution into the stationary state of complex nanoelectronic systems.
description: 48 pages, 14 figures, Topical Review for Nanotechnology
Critical interfaces and duality in the Ashkin Teller model
Creators: name: Picco, Marco
name: Santachiara, Raoul
Publisher: name: arXiv
Year: 2010
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We report on the numerical measures on different spin interfaces and FK cluster boundaries in the Askhin-Teller (AT) model. For a general point on the AT critical line, we find that the fractal dimension of a generic spin cluster interface can take one of four different possible values. In particular we found spin interfaces whose fractal dimension is d_f=3/2 all along the critical line. Further, the fractal dimension of the boundaries of FK clusters were found to satisfy all along the AT critical line a duality relation with the fractal dimension of their outer boundaries. This result provides a clear numerical evidence that such duality, which is well known in the case of the O(n) model, exists in a extended CFT.
description: 5 pages, 4 figures
General Relativity and Quantum Mechanics in Five Dimensions
Creators: name: Wesson, Paul S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Physics (physics.gen-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In 5D, I take the metric in canonical form and define causality by null-paths. Then spacetime is modulated by a factor equivalent to the wave function, and the 5D geodesic equation gives the 4D Klein-Gordon equation. These results effectively show how general relativity and quantum mechanics may be unified in 5D.
Study of electron spin dynamics in grain aligned LaCoPO: an itinerant ferromagnet
Creators: name: Majumder, M.
name: Ghoshray, K.
name: Ghoshray, A.
name: Bandyopadhyay, B.
name: Ghosh, M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: 139La NMR study was performed in grain aligned (c|| H0) sample of LaCoPO and polycrystalline LaFePO. Knight shift is isotropic and temperature independent in LaFePO. It is strongly temperature dependent and anisotropic in LaCoPO. The spin-lattice relaxation rate in LaCoPO clearly reveals the existence of 3D spin fluctuations both in the paramagnetic and ferromagnetic state over and above the dominant 2D spin fluctuations in the paramagnetic state, observed earlier from 31P NMR measurements in the same oriented sample. The spin fluctuation parameters in LaCoPO determined from 139La NMR relaxation and magnetization data, using the self consistent renormalization (SCR) theory, are in close agreement and follow the universal Rhodes-Wohlfarth curve.
description: Accepted in PRB
Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer
Creators: name: Kim, Ga Hee
name: Won, Ji Eun
name: Byeon, Yeongseon
name: Kim, Min Gi
name: Wi, Tae In
name: Lee, Jae Myeong
name: Park, Yun-Yong
name: Lee, Jeong-Won
name: Heung Kang, Tae
name: Jung, In Duk
name: Shin, Byung Cheol
name: Ahn, Hyung Jun
name: Lee, Young Joo
name: Sood, Anil K.
name: Han, Hee Dong
name: Park, Yeong-Min
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Angiogenesis plays an essential role in the growth and metastasis of tumor cells, and the modulation of angiogenesis can be an effective approach for cancer therapy. We focused on silencing the angiogenic gene PLXDC1 as an important factor for anti-angiogenesis tumor therapy. Herein, we developed PLXDC1 small interfering siRNA (siRNA)-incorporated chitosan nanoparticle (CH-NP/siRNA) coated with hyaluronic acid (HA) to target the CD44 receptor on tumor endothelial cells. This study aimed to improve targeted delivery and enhance therapeutic efficacy for tumor anti-angiogenesis. The HA-CH-NP/siRNA was 200 ± 10 nm in size with a zeta potential of 26.4 mV. The loading efficiency of siRNA to the HA-CH-NP/siRNA was up to 60%. The selective binding of HA-CH-NP/siRNA to CD44-positive tumor endothelial cells increased by 2.1-fold compared with that of the CD44 nontargeted CH-NP/siRNA. PLXDC1 silencing by the HA-CH-NP/siRNA significantly inhibited tumor growth in A2780 tumor-bearing mice compared with that in the control group (p p p p
Substance use and school connectedness among street-involved youth in British Columbia : a mixed-methods study
Creators: name: Rivers, Robert
Publisher: name: University of British Columbia
Year: 2018

description: Street-involved youth face difficulties due to their precarious living situation. Substance use is higher among these youth compared to the general youth population. This study examines the relationship between street-involved youth and school connection on their problem substance use. Problem substance use was defined as using marijuana 20 or more times a month, binge drinking alcohol three or more times a month, and facing consequences from severe substance use. The study design was a two-step sequential mixed-methods approach, beginning with a quantitative analysis using probability profiling via logistic regression with 762 street-involved youth ages 12 to 18 who responded to the province wide 2006 British Columbia Street-Involved Youth Survey in Canada. The second step used qualitative interviews to collect qualitative data with street-involved youth enrolled in school the previous year and identified using substances. Themes were identified from their experiences with substance use while in school. The probability profiling analyses uncovered school connectedness influenced problem substance use differently for young women and men. The presence of school connectedness decreased the probability of Problem Alcohol Use from 32% to 17% for young men and provided a 25% overall reduction in probability among known risk factors. The probability of Problem Marijuana Use decreased from 33% to 18% for young women as school connectedness increased; school connectedness reduced risk factors by 18%. Consequences from Substance Use was marginally protected against for young women, but school attendance protected against consequences for young men by 12%, in the presence of known risk factors. The second step examined qualitative data collected from interviews with four young women and seven young men who were street-involved in Vancouver, Canada at the time of the study. The age for youth participation was 16 to 24; they must been in school for a month over the past year and used substances while attending school. The recruited youth were between ages 16 and 21. They said having one caring adult in school, participating in extracurricular activities, and attending schools with zero tolerance policies toward substance use were ineffective in reducing substance use or creating stronger connections to school.
Holographic gratings for cold neutron optics
Creators: name: Fally, Martin
name: Klepp, Juergen
name: Pruner, Christian
name: Tomita, Yasuo
name: Eckerlebe, Helmut
name: Kohlbrecher, Joachim
name: Rupp, Romano A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We discuss the applicability of holographically patterned polymers, polymer dispersed liquid crystals, and nanoparticle-polymer composites as optical elements for cold neutrons. Requirements concerning the spacing, thickness or strength of the grating for certain types of neutron optical elements, e.g., 2-port or 3-port beamsplitters, are discussed in the framework of a rigorous coupled-wave analysis. Finally, a roadmap to neutron mirrors, e.g., for interferometers, is drawn.
description: 4 pages, 2 figures, Information Photonics 2011, Ottawa, Canada
A Conversation with James Hannan
Creators: name: Gilliland, Dennis
name: Ramamoorthi, R. V.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Other Statistics (stat.OT)
subject: FOS: Computer and information sciences

description: Jim Hannan is a professor who has lived an interesting life and one whose fundamental research in repeated games was not fully appreciated until late in his career. During his service as a meteorologist in the Army in World War II, Jim played poker and made weather forecasts. It is curious that his later research included strategies for repeated play that apply to selecting the best forecaster. James Hannan was born in Holyoke, Massachusetts on September 14, 1922. He attended St. Jerome's High School and in January 1943 received the Ph.B. from St. Michael's College in Colchester, Vermont. Jim enlisted in the US Army Air Force to train and serve as a meteorologist. This took him to army airbases in China by the close of the war. Following discharge from the army, Jim studied mathematics at Harvard and graduated with the M.S. in June 1947. To prepare for doctoral work in statistics at the University of North Carolina that fall, Jim went to the University of Michigan in the summer of 1947. The routine admissions' physical revealed a spot on the lung and the possibility of tuberculosis. This caused Jim to stay at Ann Arbor through the fall of 1947 and then at a Veterans Administration Hospital in Framingham, Massachusetts to have his condition followed more closely. He was discharged from the hospital in the spring and started his study at Chapel Hill in the fall of 1948. There he began research in compound decision theory under Herbert Robbins. Feeling the need for teaching experience, Jim left Chapel Hill after two years and short of thesis to take a three year appointment as an instructor at Catholic University in Washington, DC. When told that renewal was not coming, Jim felt pressure to finish his degree.
description: Published in at http://dx.doi.org/10.1214/09-STS283 the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Measuring the Sizes, Shapes, Surface Features and Rotations of Solar System Objects with Interferometry
Creators: name: Li, Jian-Yang
name: Kuchner, Marc J.
name: Allen, Ronald J.
name: Sheppard, Scott S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We consider the application of interferometry to measuring the sizes and shapes of small bodies in the solar system that cannot be spatially resolved by today's single-dish telescopes. Assuming ellipsoidal shapes, our results indicate that interferometers can measure the size of an object to better than 15% uncertainty if the limb-darkening is unknown. Assuming a Minnaert scattering model, one can theoretically derive the limb-darkening parameters from simultaneous measurements of visibilities at several different projected baseline lengths to improve the size and shape determination to an accuracy of a few percent. With a 3-D shape model for the dwarf planet Haumea, we demonstrate that when photometric light curve, visibility light curve, and visibility phase center displacement are combined, the rotational period and sense of rotation can all be derived, and the rotational pole can be estimated. Because of its elongated shape and the dark red spot, the rotation of Haumea causes its optical photocenter to move in a loop on the sky, extending of ~80 \muas without the dark red spot, and ~200 \muas with it. Such movements are easily detectable by space-based astrometric interferometer designed e.g. for planet detection. As an example, we consider the possible contributions to the study of small bodies in the solar system by the Space Interferometry Mission. We show that such a mission could make substantial contributions in characterizing the fundamental physical properties of the brightest Kuiper Belt Objects and Centaurs as well as a large number of main belt asteroids. We compile a list of Kuiper Belt Objects and Centaurs that are potentially scientifically interesting and observable by such missions.
description: 44 pages, 8 figures, 1 table
Stochastic process behind nonlinear thermodynamic quantum master equation
Creators: name: Öttinger, Hans Christian
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We propose a piecewise deterministic Markovian jump process in Hilbert space such that the covariance matrix of this stochastic process solves the thermodynamic quantum master equation. The proposed stochastic process is particularly simple because the normalization of the vectors in Hilbert space is preserved only on average. As a consequence of the nonlinearity of the thermodynamic master equation, the construction of stochastic trajectories involves the density matrix as a running ensemble average. We identify a principle of detailed balance and a fluctuation-dissipation relation for our Markovian jump process.
description: 4 pages
Application of Platelet-Rich Plasma in Orthodontics
Creators: name: Samruajbenjakun, Bancha
Publisher: name: The Dental Association of Thailand
Year: 2019
Subjects: Tooth movement
Growth factors
Cytokines
Orthodontics
Platelet-rich plasma (PRP)

description: Journal of The Dental Association of Thailand, 69, 2, 126-133
Nasal delivery of H5N1 avian influenza vaccine formulated with GenJet™ or in vivo-jetPEI® induces enhanced serological, cellular and protective immune responses
Creators: name: Cao, Weiping
name: Mishina, Margarita
name: Amoah, Samuel
name: Mboko, Wadzanai P.
name: Bohannon, Caitlin
name: McCoy, James
name: K. Mittal, Suresh
name: Gangappa, Shivaprakash
name: Sambhara, Suryaprakash
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Avian influenza virus infection is a serious public health threat and preventive vaccination is the most cost-effective public health intervention strategy. Unfortunately, currently available unadjuvanted avian influenza vaccines are poorly immunogenic and alternative vaccine formulations and delivery strategies are in urgent need to reduce the high risk of avian influenza pandemics. Cationic polymers have been widely used as vectors for gene delivery in vitro and in vivo. In this study, we formulated H5N1 influenza vaccines with GenJet™ or in vivo-jetPEI®, and showed that these formulations significantly enhanced the immunogenicity of H5N1 vaccines and conferred protective immunity in a mouse model. Detailed analyses of adaptive immune responses revealed that both formulations induced mixed TH1/TH2 antigen-specific CD4 T-cell responses, antigen-specific cytotoxic CD8 T-cell and memory B-cell responses. Our findings suggest that cationic polymers merit future development as potential adjuvants for mucosal delivery of poorly immunogenic vaccines.
The management of surgical defect in A Patient with First Stage I Low-Grade Mucoepidermoid Carcinoma Using An Obturator Prosthesis : A Case Report
Creators: name: Kodkeaw, Panarat
Publisher: name: The Dental Association of Thailand
Year: 2019
Subjects: Surgery
Obturator
Early stage oral cancer
Oro-nasal communication

description: Journal of The Dental Association of Thailand, 69, 2, 142-150
Isoscalar dipole coherence at low energies and forbidden E1 strength
Creators: name: Papakonstantinou, P.
name: Ponomarev, V. Yu.
name: Roth, R.
name: Wambach, J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Theory (nucl-th)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: In 16O and 40Ca an isoscalar, low-energy dipole transition (IS-LED) exhausting approximately 4% of the isoscalar dipole (ISD) energy-weighted sum rule is experimentally known, but conspicuously absent from recent theoretical investigations of ISD strength. The IS-LED mode coincides with the so-called isospin-forbidden E1 transition. We report that for N=Z nuclei up to 100Sn the fully self-consistent Random-Phase-Approximation with finite-range forces, phenomenological and realistic, yields a collective IS-LED mode, typically overestimating its excitation energy, but correctly describing its IS strength and electroexcitation form factor. The presence of E1 strength is solely due to the Coulomb interaction between the protons and the resulting isospin-symmetry breaking. The smallness of its value is related to the form of the transition density, due to translational invariance. The calculated values of E1 and ISD strength carried by the IS-LED depend on the effective interaction used. Attention is drawn to the possibility that in N-not-equal-Z nuclei this distinct mode of IS surface vibration can develop as such or mix strongly with skin modes and thus influence the pygmy dipole strength as well as the ISD strength function. In general, theoretical models currently in use may be unfit to predict its precise position and strength, if at all its existence.
description: 9 pages, 6 figures, EPJA submitted
Living between worlds : an autoethnographic exploration of individualized and entangled third space
Creators: name: Bethell (Natoo Ain Nis Soo), Peter Arthur
Publisher: name: University of British Columbia
Year: 2018

description: I had the honour of being able to attend two Sun Dance ceremonies in Southern Alberta, and found them to be transformative. The purpose of this study is to reflect on my identity as a product of colonisation and how participation in Indigenous ceremony, specifically the Sun Dance, impacted me both as an individual and as an educator. The guiding research questions are: why was the ceremony so impactful; how did participation in the Sun Dance help to increase knowledge and understanding of Indigenous cultures; how did participation in ceremony impact my third space identity; and how did my experience strengthen me as a critical ontologist. An autoethnographic methodology was chosen in part because personal stories have impact and can change the way the reader understands and navigates the world. It also gives voice to the marginalised, and can be more accessible to readers from various backgrounds. The data presented comes from self-reflection, reviewing relevant literature, and discussions with Elders. Supporting artifacts are included in the appendix. This autoethnography is grounded in three major philosophical schools: Indigenous ways of knowing and being, critical theory, and decolonial/post-colonial theories. Specifically, I connect myself and my work to two philosophies derived from these schools: Homi Bhabha’s third space, and Joe Kincheloe’s critical ontology. The former focuses on cultural hybridity, which describes my identity, while the latter combines Indigenous and non-Indigenous viewpoints, which describes my praxis. Immersion in ceremony, and self-reflection, provided a deeper understanding of myself and my place in the world, and impacted the ways in which I interpret information and relate to others. I gained a deeper appreciation of Indigenous cultures, and began to see how ceremony is both a powerful healing and teaching tool. I concluded that ethical teaching requires a classroom where everyone’s differences, cultures, and ways of being are respected and brought together to inform daily practice. Participation in cultural practices, including but not limited to ceremony, would help provide a multifaceted perspective by which one could more accurately evaluate their own sociocultural and political values, ethics, and practices both as a person and as an educator.
Drug delivery systems based on biocompatible imino-chitosan hydrogels for local anticancer therapy
Creators: name: Ailincai, Daniela
name: Mititelu, Liliana Tartau
name: Marin, Luminita
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: A series of drug delivery systems were prepared by chitosan hydrogelation with citral in the presence of an antineoplastic drug: 5-fluorouracil. The dynamic covalent chemistry of the imine linkage allowed the obtaining of supramolecular tridimensional architectures in which the drug has been homogenously dispersed. Fourier-transform infrared spectroscopy (FTIR), wide-angle X-ray diffraction (WXRD) and polarized light microscopy (POM) measurements were used in order to follow the hydrogelation and drug encapsulation processes. The ability of the prepared systems to release the drug has been investigated by UV–Vis spectroscopy using a calibration curve and by fitting the results with different mathematic models. To mimic the behavior of the hydrogel matrix in bio-environmental conditions in view of applications, their enzymatic degradability was monitored in the presence of lysozyme. The in vivo side effects of the systems, in terms of their influence on the blood elements, biochemical and immune parameters were monitored on white Swiss mice by intraperitoneal administration of the injectable obtained hydrogels. All the characteristics of the obtained systems, such as micro-porous morphology, uniform drug encapsulation, enzymatic degradability, lack of side effects, other than the one of the drug itself, along with their ability to release the drug in a sustained manner proved that these material meet the requirements for the development of drug delivery systems, making them suitable for being applied in intraperitoneal chemotherapy.
Living on the edge of chaos: minimally nonlinear models of genetic regulatory dynamics
Creators: name: Hanel, Rudolf
name: Pöchacker, Manfred
name: Thurner, Stefan
Publisher: name: arXiv
Year: 2010
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Molecular Networks (q-bio.MN)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Linearized catalytic reaction equations modeling e.g. the dynamics of genetic regulatory networks under the constraint that expression levels, i.e. molecular concentrations of nucleic material are positive, exhibit nontrivial dynamical properties, which depend on the average connectivity of the reaction network. In these systems the inflation of the edge of chaos and multi-stability have been demonstrated to exist. The positivity constraint introduces a nonlinearity which makes chaotic dynamics possible. Despite the simplicity of such minimally nonlinear systems, their basic properties allow to understand fundamental dynamical properties of complex biological reaction networks. We analyze the Lyapunov spectrum, determine the probability to find stationary oscillating solutions, demonstrate the effect of the nonlinearity on the effective in- and out-degree of the active interaction network and study how the frequency distributions of oscillatory modes of such system depend on the average connectivity.
description: 11 pages, 5 figures
An in vivo study of Hypericum perforatum in a niosomal topical drug delivery system
Creators: name: Ali, Mohamed
name: Motaal, Amira Abdel
name: Ahmed, Mohammed A.
name: Alsayari, Abdulrhman
name: El-Gazayerly, Omaima N.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: The active compounds present in Hypericum perforatum L. (Hypericaceae) include hyperforin, hypericins and flavonoids, which are assumed to be responsible for the activity of the extract in the treatment of wounds and scars. The present study aimed to incorporate H. perforatum extract standardized to a known content of phloroglucinols, naphthodianthrones and polyphenolic compounds into an effective transdermal drug delivery system capable of entrapping both lipophilic and hydrophilic constituents in the form of niosomal gels for wound treatment. An 80% ethanol extract (HE) was prepared on a pilot scale using DIG-MAZ. An HPLC-DAD holistic profile was established for HE and was standardized to contain 3.4 ± 4 rutin, 1.1 ± 3 chlorogenic acid, 0.5 ± 2 quercitrin, 2.8 ± 2 hyperforin, and 0.51 ± 3% w/w total hypericins. Niosomes were prepared using the modified reverse phase evaporation technique (REV). The wound healing effect of the gel was tested on 16 adult mongrel dogs. A significant decrease in the inflammatory cell count (18.4 ± 5.3) was recorded in the niosomal gel 1.5% NaCMC-treated group at the 7th day post wounding. It induced a marked regression in the inflammatory phase and enhanced the early beginning of the proliferative phase of wound healing. After 21 days, it showed complete re-epithelization, formation of new matrix fibers and significant reduction in the wound size, compared to the control and the Panthenol® 2% cream treated groups. This is the first study of H. perforatum in a niosomal topical drug delivery system.
Multistage delivery of CDs-DOX/ICG-loaded liposome for highly penetration and effective chemo-photothermal combination therapy
Creators: name: Xue, Xiao
name: Fang, Ting
name: Yin, Luyao
name: Jiang, Jianqi
name: He, Yunpeng
name: Dai, Yinghui
name: Wang, Dongkai
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Cancer
subject: Computational Biology

description: Nanoparticles (NPs) have proven to be effective drug carriers in diagnosis and therapy of cancer. But, they faced a contradictory issue that NPs with large size appear weak tumor penetration, meanwhile small size resulted in poor tumor retention. Herein, we fabricated doxorubicin conjugated carbon dots (CDs-DOX) and indocyanine green (ICG)-loaded liposomes (ICG-LPs) named CDs-ICG-LPs using a modified reverse phase evaporation process, and with high incorporation in the aqueous core. The CDs-ICG-LPs exhibited good monodispersity, excellent fluorescence/size stability, and consistent spectra characteristics compared with free ICG or DOX. Moreover, the CDs-ICG-LPs showed higher temperature response, faster DOX release under laser irradiation. In the meantime, the fluorescence of DOX and ICG in CDs-ICG-LPs was also visualized for the process of subcellular location in vitro. In comparison with chemo or photothermal treatment alone, the combined treatment of CDs-ICG-LPs with laser irradiation synergistically induced the apoptosis and death of DOX-sensitive HepG2 cells. In vivo antitumor activities demonstrated CDs-ICG-LPs could reach higher antitumor activity compared with CDs-DOX and ICG-LPs for H22 tumor cells, and suppressed H22 tumor growth in vivo. Notably, no systemic toxicity occurrence was observed after repeated dose of CDs-ICG-LPs with laser irradiation. Hence, the well-defined CDs-ICG-LPs exhibited great potential in targeting cancer imaging and chemo-photothermal therapy.
Rare $B$ Decays Potential at Super$B$
Creators: name: Rakitin, Alexander
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present a short overview of the most important rare $B$ decay analyses which will be performed using $75~{\rm ab}^{-1}$ dataset which is expected to be provided by Super$B$ Factory within five years from its starting date.
description: 7 pages, 5 figures, Proceedings of the Xth Nicola Cabibbo International Conference on Heavy Quarks and Leptons, October 11-15, 2010, Frascati (Rome) Italy