cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Curvature Constraints from the Causal Entropic Principle
Creators: name: Bozek, Brandon
name: Albrecht, Andreas
name: Phillips, Daniel
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Current cosmological observations indicate a preference for a cosmological constant that is drastically smaller than what can be explained by conventional particle physics. The Causal Entropic Principle (Bousso, {\it et al}.) provides an alternative approach to anthropic attempts to predict our observed value of the cosmological constant by calculating the entropy created within a causal diamond. We have extended this work to use the Causal Entropic Principle to predict the preferred curvature within the "multiverse". We have found that values larger than $ρ_k = 40ρ_m$ are disfavored by more than 99.99% and a peak value at $ρ_Λ = 7.9 \times 10^{-123}$ and $ρ_k =4.3 ρ_m$ for open universes. For universes that allow only positive curvature or both positive and negative curvature, we find a correlation between curvature and dark energy that leads to an extended region of preferred values. Our universe is found to be disfavored to an extent depending the priors on curvature. We also provide a comparison to previous anthropic constraints on open universes and discuss future directions for this work.
description: 5 pages, 3 Figures
Formulate a concentrated highly branched poly(β-amino ester)/DNA polyplex – one step closer to application in lung cystic fibrosis disease
Creators: name: Qiu, Bei
name: Li, Yinghao
name: He, Zhonglei
name: Li, Zishan
name: Terreau, Sébastien
name: Wang, Xianqing
name: Lyu, Jing
name: Wang, Wenxin
name: Lara-Sáez, Irene
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Astronomical and Space Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Highly branched poly(β-amino ester) (HPAEs)-based gene therapy holds promise for treating lung cystic fibrosis (CF). However, the translation of HPAEs/DNA nanoparticles into clinical applications poses a significant challenge due to the requirement for high concentrations of the formulation. In this work, a straightforward and scalable concentration method was developed for concentrating HPAEs/DNA polyplexes. A series of different buffers with various pH values and ionic components were initially tested to develop the optimized HPAEs/DNA polyplex formulation. Subsequently, the optimized HPAEs/DNA polyplex formulation was concentrated through lyophilization and ultrafiltration. The ultrafiltration outperformed the lyophilization in concentration capacity, showing a 24-fold increase in the concentrated formulation compared to the original non-concentrated formulation. The concentration does not disturb the transfection efficiency in lung CF epithelial cells, indicating its potential for lung delivery applications. Moreover, the concentrated HPAEs/DNA polyplex successfully restored the production of CF transmembrane conductance regulator (CFTR) protein in primary lung CF epithelial cells, surpassing the performance of the non-concentrated common gene transfection reagents such as Lipofectamine 3000 and Xfect. The concentrated HPAEs/DNA formulation represents a promising step forward for preclinical testing (e.g. in vivo evaluation), with further research needed to confirm its potential for clinical use. The processes of concentrating HPAEs/DNA polyplexes.
Astronomy rewind, un progetto di citizen science
Creators: Francesca Aloisio
Publisher: name: Media Inaf
Year: 2017

È l’ultimo progetto di citizen science, ovvero di scienza dal basso, lanciato sulla piattaforma Zoouniverse. Si chiama Astronomy Rewind e darà una nuova vita alle foto e alle mappe stellari contenute nei testi di astronomia o in vecchie riviste. Come? Inserendo le scansioni effettuate negli atlanti digitali del cielo in modo che i cittadini possano confrontarle con i dati acquisiti dai moderni telescopi da terra e spaziali. E chissà cosa potrebbe venir fuori da queste analisi comparate sui cambiamenti avvenuti in cielo
C’è una miniera di ferro in quelle pulsar
Creators: Paolo Soletta
Publisher: name: Media Inaf
Year: 2017

Scoperta una riga di emissione del ferro a 6-7 keV negli spettri dell’emissione X della pulsar doppia Psr J0737-3039. I risultati, pubblicati su ApJ, grazie a un team guidato da Alberto Pellizzoni e composto dalle astrofisiche Elise Egron e Maria Noemi Iacolina
Session-Based Programming for Parallel Algorithms: Expressiveness and Performance
Creators: name: Bejleri, Andi
name: Hu, Raymond
name: Yoshida, Nobuko
Publisher: name: arXiv
Year: 2010
Subjects: subject: Programming Languages (cs.PL)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: This paper investigates session programming and typing of benchmark examples to compare productivity, safety and performance with other communications programming languages. Parallel algorithms are used to examine the above aspects due to their extensive use of message passing for interaction, and their increasing prominence in algorithmic research with the rising availability of hardware resources such as multicore machines and clusters. We contribute new benchmark results for SJ, an extension of Java for type-safe, binary session programming, against MPJ Express, a Java messaging system based on the MPI standard. In conclusion, we observe that (1) despite rich libraries and functionality, MPI remains a low-level API, and can suffer from commonly perceived disadvantages of explicit message passing such as deadlocks and unexpected message types, and (2) the benefits of high-level session abstraction, which has significant impact on program structure to improve readability and reliability, and session type-safety can greatly facilitate the task of communications programming whilst retaining competitive performance.
Nuova mappa 3D della polvere galattica
Creators: Elisa Nichelli
Publisher: name: Media Inaf
Year: 2017

Grazie al dettaglio delle immagini raccolte da alcuni tra i telescopi più sensibili alle lunghezze d’onda dell’ottico e dell’infrarosso, un team di ricercatori ha ottenuto la mappa 3D più dettagliata di sempre della polvere nella Via Lattea. Le distanze coprono più di 3.000 anni luce dal Sole, e mostrano un quadro più complesso rispetto a ciò che prevedeva la teoria
A study of the pathways of glucose oxidation of Pseudomonas aeruginosa
Creators: name: Reid, K. Garth
Publisher: name: University of British Columbia
Year: 2012

description: An effort has been made to demonstrate that the major pathway for glucose oxidation in Pseudomonas aeruginosa (ATCC 9027) involves the sequence of reactions: glucose →gluconate → 2-ketogluconate → 2-keto-6- phosphogluconate → 6-phosphogluconate. It appears however, that extracts of this organism are capable of phosphorylating glucose directly, that is, to yield glucose-6-phosphate and subsequently 6-phosphogluconate. A study of this latter pathway was felt to be necessary in order to evaluate the likelihood of it being a major alternative to the established non-phosphorylated pathway. Since it is known that glucose-6-phosphate dehydrogenase from P. aeruginosa and other microorganisms as well as from certain animal tissues exhibits a marked sensitivity to various nucleotides particularly to adenosine triphosphate. A study of this inhibition was made in order to assess the possible role that this sensitivity may play in determining the importance of this pathway as the major route of glucose oxidation. Enzyme fractionation studies revealed that hexokinase and glucose-6-phosphate dehydrogenase could be separated either by an ethanol fractionation or by an alkaline ammonium sulfate fractionation. The best separation of dehydrogenase was obtained using ethanol although hexokinase could only be isolated using the alkaline ammonium sulfate method. Cell free extracts of P. aeruginosa oxidize glucose to 2-keto-gluconate but carry the reaction no further. This represents a consumption of l µM of oxygen per µM glucose. In the presence of ATP the amount of oxygen consumed was reduced to a maximum of 0.5 µM per µM glucose, indicating the accumulation of a compound less oxidized than 2-ketogluconic acid. 6-phosphogluconate appeared to conform to the requirements of such a compound. Chromatographic analysis of reaction mixtures containing ATP revealed the accumulation of a phosphorylated compound which could not be identified. Under in vitro conditions both pathways appear to be operable but the non-phosphorylated pathway accounts for most of the glucose in the metabalizing organism.
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð¿Ð¾Ð´ Ð¾Ð¿ÐµÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÑ ÑÐ¸ÑÑÐµÐ¼Ñ Android Ð´Ð»Ñ Ð¸Ð·ÑÑÐµÐ½Ð¸Ñ Ð¸ÑÐ°Ð»ÑÑÐ½ÑÐºÐ¾Ð³Ð¾ ÑÐ·ÑÐºÐ°
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ²ÑÐµÐ¿ÑÐ½, ÐÐ½ÑÑÐ¸Ðº
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½Ð¾Ðµ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ
Ð¼ÐµÑÐ¾Ð´ Ð¸Ð½ÑÐµÑÐ²Ð°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¿Ð¾Ð²ÑÐ¾ÑÐµÐ½Ð¸Ñ
Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð°Ñ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð´Ð»Ñ Ð¸Ð·ÑÑÐµÐ½Ð¸Ñ Ð¸ÑÐ°Ð»ÑÑÐ½ÑÐºÐ¾Ð³Ð¾ ÑÐ·ÑÐºÐ°. ÐÑÐ¸ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ð¸ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð±ÑÐ»Ð¸ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Android Studio - Ð¸Ð½ÑÐµÐ³ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½Ð°Ñ ÑÑÐµÐ´Ð° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð´Ð»Ñ ÑÐ°Ð±Ð¾ÑÑ Ñ Ð¿Ð»Ð°ÑÑÐ¾ÑÐ¼Ð¾Ð¹ Android, Ð°ÑÑÐ¸ÑÐµÐºÑÑÑÐ° Model View-Model View, ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸Ñ Material Design. ÐÑÐ»Ð¸ Ð¸Ð·ÑÑÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÐºÐ¾Ð¼Ð¿Ð¾Ð½ÐµÐ½ÑÑ, Ð¸Ð· ÐºÐ¾ÑÐ¾ÑÑÑ ÑÐ¾ÑÑÐ¾Ð¸Ñ Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½Ð¾Ðµ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ Ð´Ð»Ñ Ð¾Ð¿ÐµÑÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Android ÑÐ°ÐºÐ¸Ðµ ÐºÐ°Ðº: Activity, Fragment, Android Manifest, Layout- ÑÐ°Ð¹Ð»Ñ Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð½ÑÐµ Ð±Ð¸Ð±Ð»Ð¸Ð¾ÑÐµÐºÐ¸, Ð¸ÑÐ¿Ð¾Ð»ÑÐ·ÑÐµÐ¼ÑÐµ Ð² Ð¿ÑÐ¾ÑÐµÑÑÐµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸: v7 recyclerview library, v7 cardview library, Sugar ORM, Android Support Library, Data Binding Library Ð ÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð¼ Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ, Ð´Ð¸Ð·Ð°Ð¹Ð½Ð° Ð¸ Ð½Ð°Ð¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ðµ Ð±Ð°Ð·Ñ Ð´Ð°Ð½Ð½ÑÑ, ÐºÐ¾ÑÐ¾ÑÐ°Ñ ÑÐ¾Ð´ÐµÑÐ¶Ð¸Ñ Ð²ÑÑ Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼ÑÑ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ñ Ð´Ð»Ñ Ð¸Ð·ÑÑÐµÐ½Ð¸Ñ Ð¸ÑÐ°Ð»ÑÑÐ½ÑÐºÐ¾Ð³Ð¾ ÑÐ·ÑÐºÐ°. Ð¡Ð¾Ð·Ð´Ð°Ð½Ð½Ð¾Ðµ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ Ð¾ÑÐ²ÐµÑÐ°ÐµÑ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÐ¼ ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸ÑÐ¼, Ð¿ÑÐµÐ´ÑÑÐ²Ð»ÑÐµÐ¼ÑÐ¼ Ðº Ð´Ð¸Ð·Ð°Ð¹Ð½Ñ Ð¸ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»Ñ, ÑÐµÐ°Ð»Ð¸Ð·Ð¾Ð²Ð°Ð½Ð¾ Ñ ÑÑÐµÑÐ¾Ð¼ ÑÑÐ°Ð½Ð´Ð°ÑÑÐ¾Ð² Google.
Additional file 14 of Residual periodontal ligament in the extraction socket promotes the dentin regeneration potential of DPSCs in the rabbit jaw
Creators: name: Luo, Bin
name: Luo, Yu
name: He, Lin
name: Cao, Yangyang
name: Jiang, Qingsong
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 14: GO functions of differentially expressed miRNA target mRNAs in DPSCs regulated by PDLSCs.
AQbD integrated high-performance thin layer chromatographic method for quantitative estimation of Tavaborole in the presence of its degradants and the matrix of nanostructured lipid carriers
Creators: name: Patel, Rashmin
name: Neel, Savaliya
name: Mrunali, Patel
name: Patel, Yash
name: Dave, Richa
name: Vikas, Agrawal
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Tavaborole (TAV), a benzoxaborole derivative, is an FDA-approved antifungal agent for treating onychomycosis, a common and persistent fungal infection of the toenails. This study aimed to develop a robust stability-indicating HPTLC method to determine TAV in nanostructured lipid carriers (NLC) using a comprehensive approach that includes risk assessment, and Analytical Quality by Design. The critical method parameters influencing the HPTLC results were screened using a Plackett-Burman screening design followed by its optimization using a central composite optimization design. The developed method was validated as per ICH recommendation. Optimized method utilized pre-coated aluminum-backed HPTLC plates using 10 µL/band injection volume, and the plate was developed using an isocratic mobile phase consisting of toluene: ethyl acetate: formic acid (75:25:1%v/v/v) in twin trough chamber pre-saturated for 20 mins with vapors of 10 mL of mobile phase. The separated components were detected at a wavelength of 221 nm. The developed HPTLC method resulted in a retardation factor of 0.49 ± 0.04 for TAV. Validation results revealed the HPTLC method’s specificity (peak purity ≥ 0.999), linearity over a concentration range of 2–10 μg/band, sensitivity (LOD 0.21 μg and LOQ 0.64 μg), accuracy (99.68 − 101.43%w/w), and precision (%RSD < 2.0). The developed robust stability-indicating HPTLC method was successfully implemented for the sustainable testing of the TAV in the NLC formulations and stability testing.
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐ¸ÑÑÐµÐ¼Ñ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ¾Ð¼ ÑÐ°ÑÐ¿ÑÐµÐ´ÐµÐ»ÑÐ½Ð½ÑÑ Ð²ÑÑÐ¸ÑÐ»ÐµÐ½Ð¸Ð¹ Ð½Ð° Ð±Ð°Ð·Ðµ Ð¿Ð»Ð°ÑÑÐ¾ÑÐ¼Ñ Kubernetes
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐµÐ·Ð½Ð¾Ñ, Ð®ÑÐ¸Ð¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÑÐ¸ÑÑÐµÐ¼Ð½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð·
ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ
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kubernetes
linux

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ Ð¿Ð»Ð°ÑÑÐ¾ÑÐ¼Ð° Kubernetes ÐºÐ°Ðº Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½Ñ Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ¾Ð¼ ÑÐ°ÑÐ¿ÑÐµÐ´ÐµÐ»ÑÐ½Ð½ÑÑ Ð²ÑÑÐ¸ÑÐ»ÐµÐ½Ð¸Ð¹.
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L’universo dei campi magnetici giganti
Creators: Davide Coero Borga
Publisher: name: Media Inaf
Year: 2017

I più estesi di sempre nell’universo conosciuto: sono gli eccezionali campi magnetici scoperti nei pressi degli ammassi di galassie CIZA J2242+53, distribuiti su diversi milioni di anni luce e rilevati grazie ai dati raccolti dal radiotelescopio Effelsberg
title:  L’emergenza pandemica come innesco della crisi delle democrazie illiberali negli ordinamenti costituzionali ungherese e polacco
Creators: name: Benvenuti  ,  Simone
Publisher: name: Roma TrE-Press
Year: 2022

description: Questo articolo riflette sull’impatto della crisi pandemica sullo stato delle democrazie illiberali in Ungheria e Polonia. Ritiene che nel 2020 e nel 2021 i due regimi abbiano subito una perdita di legittimità e ciò abbia esacerbato gli elementi di resistenza al loro consolidamento. L’analisi, che mira a contribuire alla discussione teorica sulla natura delle democrazie illiberali, dopo aver presentato il quadro costituzionale per emanare lo stato di emergenza nei due paesi e la relativa prassi, si concentra sugli sviluppi in tre aree: sistema di governo, regime e rapporti con l’Unione Europea. Si conclude quindi situando l’analisi nella prospettiva delle tradizioni costituzionali ungherese e polacca.
description: Democrazia e Sicurezza – 2021 n. 3
Come fare un buco (nero) nell’elio
Creators: Stefano Parisini
Publisher: name: Media Inaf
Year: 2017

Le simulazioni al computer di una sfera di 64 atomi di elio quasi allo zero assoluto immersa in un bagno superfluido dello stesso elemento rivelano lo stesso effetto quantistico “olografico”  di un buco nero, che collega l'entropia di un buco nero all'area della sua “superficie” e non al suo volume
The RMS Survey: 6 cm continuum VLA observations towards candidate massive YSOs in the northern hemisphere
Creators: name: Urquhart, J. S.
name: Hoare, M. G.
name: Purcell, C. R.
name: Lumsden, S. L.
name: Oudmaijer, R. D.
name: Moore, T. J. T.
name: Busfield, A. L.
name: Mottram, J. C.
name: Davies, B.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: (Abridged) Context: The Red MSX Source (RMS) survey is an ongoing multi-wavelength observational programme designed to return a large, well-selected sample of massive young stellar objects (MYSOs). We have identified $\sim$2000 MYSO candidates located throughout the Galaxy by comparing the colours of MSX and 2MASS point sources to those of known MYSOs. Aims: To identify the populations of UCHII regions and PNe within the sample and examine their Galactic distribution. Method: We have conducted high resolution radio continuum observations at 6 cm towards 659 MYSO candidates in the northern hemisphere ($10\degr< l < 250\degr$) using the VLA. In addition to these targeted observations we present archival data towards a further 315 RMS sources extracted from a previous VLA survey of the inner Galaxy. Results: We find radio emission towards 272 ($\sim$27% of the observed sample). Using results from other parts of our multi-wavelength survey we separate these RMS-radio associations into two distinct types of objects, classifying 51 as PNe and a further 208 as either compact or UC HII regions. Using this well selected sample of HII regions we estimate their Galactic scale height to be 0.6\degr. Conclusions: Using radio continuum and archival data we have identified 79 PNe and 391 HII regions within the northern RMS catalogue. We estimate the total fraction of contamination by PNe in the RMS sample is of order 10%. The sample of HII regions is probably the best representation to date of the Galactic population of HII regions as a whole.
description: Accepted for publication in Astronomy and Astrophysics. 15 pages, 9 figures and 5 tables. Full versions of Tables 3, 4 and 5 and Figs. 2, 4 and 7 will only be available via CDS or the RMS website at http:/www.ast.leeds.ac.uk/cgi-bin/RMS/RMS_VLA_IMAGES.cgi
Potent antiviral action detected in Tontelea micrantha extracts against Alphavirus chikungunya
Creators: name: Lopes, Ranieli Paiva
name: Vaz, Millena Alves Máximo
name: Ferreira, Fernanda Lopes
name: de Sousa, Grasiely Faria
name: de Brito Magalhães, Cintia Lopes
name: Vieira-Filho, Sidney Augusto
name: Ferreira, Jaqueline Maria Siqueira
name: Tótola, Antônio Helvécio
name: Duarte, Lucienir Pains
name: de Magalhães, José Carlos
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Tontelea micrantha, a notable plant species, has garnered interest for its medicinal properties, including anti-inflammatory, antibacterial and antiviral effects. A vaccine for Chikungunia virus is still under evaluation and no specific antiviral drug has been licensed to date. The work investigated antiviral activity of ethyl acetate (EAEF) and methanolic (EMF) extracts from T. micrantha leaves in mammalian cells exposed to Alphavirus chikungunya (CHIKV). The cytotoxicity, antiviral activity, selectivity index, effect on viral gene expression, virus production, and mechanisms of action were evaluated. EAEF and EMF extracts showed anti-CHIKV effects at non-cytotoxic concentrations, with CC50 above 300 μg/mL, EC50 of 18 and 43 μg/mL respectively, and selectivity Index above 4. These concentrations drastically reduce viral yields and CHIKV gene expression and have shown activity both directly on viral particles and at different stages of the viral cycle. EAEF and EMF showed robust antiviral activity against CHIKV, making them promising candidates for the development of anti-CHIKV drugs.
Indeterminazione, scacco ad Heisenberg
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2017

Il più celebre principio della meccanica quantistica è stato aggirato grazie a uno stratagemma, messo a punto all’Icfo di Barcellona,  illustrato oggi su “Nature” in un articolo il cui primo autore è il ricercatore abruzzese Giorgio Colangelo. Media Inaf lo ha intervistato
Al Cern, cinque nuovi stati per una particella
Creators: Redazione Ansa
Publisher: name: Media Inaf
Year: 2017

Hanno nomi difficili da pronunciare e pressoché impossibili da scrivere: Ωc(3000)0, Ωc(3050)0, Ωc(3066)0, Ωc(3090)0 e Ωc(3119)0. Ma esistono davvero. Li hanno scoperti al Cern di Ginevra i fisici dell’esperimento Lhcb
title: Ð¡Ð¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÐµ Ð¾Ð»Ð¸Ð¼Ð¿Ð¸Ð¹ÑÐºÐ¸Ðµ Ð¸Ð³ÑÑ ÐºÐ°Ðº Ð¿ÑÐµÐ´Ð¼ÐµÑ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÐºÐ¾-ÑÐ¾ÑÐ¸Ð°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ
title: Modern Olympic Games as a subject of economic and social researche
Creators: name: ÐÑÐµÑ, Ð.
name: ÐÑÑÐµÐ¼ÐµÐ½ÐºÐ¾Ð², Ð.
name: ÐÑÑÐµÐ¼ÐµÐ½ÐºÐ¾Ð²Ð°, Ð.
name: "Ð¡Ð¿Ð¾ÑÑ, ÑÐµÐ»Ð¾Ð²ÐµÐº, Ð·Ð´Ð¾ÑÐ¾Ð²ÑÐµ", Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐ¹ Ð½Ð°ÑÑÐ½ÑÐ¹ ÐºÐ¾Ð½Ð³ÑÐµÑÑ
Publisher: name: ÐÐÐÐÐ¢ÐÐ¥-ÐÐ ÐÐ¡Ð¡
Year: 2021
Subjects: ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÐºÐ¾-ÑÐ¾ÑÐ¸Ð°Ð»ÑÐ½ÑÐ¹ ÑÑÑÐµÐºÑ Ð¾Ð»Ð¸Ð¼Ð¿Ð¸Ð¹ÑÐºÐ¾Ð³Ð¾ Ð½Ð°ÑÐ»ÐµÐ´Ð¸Ñ
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description: Ð¦ÐµÐ»ÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ Ð°Ð½Ð°Ð»Ð¸Ð·, ÐºÐ¾ÑÐ¾ÑÑÐ¹ Ð¿Ð¾Ð·Ð²Ð¾Ð»Ð¸Ð» ÑÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°ÑÑ ÐºÑÐ¸ÑÐµÑÐ¸Ð¸ (Ð¸Ð½Ð´Ð¸ÐºÐ°ÑÐ¾ÑÑ) Ð¾ÑÐµÐ½ÐºÐ¸ Ð²ÐºÐ»Ð°Ð´Ð° ÐÐ»Ð¸Ð¼Ð¿Ð¸Ð¹ÑÐºÐ¾Ð³Ð¾ Ð½Ð°ÑÐ»ÐµÐ´Ð¸Ñ Ð² ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ðµ Ð¸ ÑÐ¾ÑÐ¸Ð°Ð»ÑÐ½Ð¾Ðµ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ðµ ÑÐµÑÑÐ¸ÑÐ¾ÑÐ¸Ð¹, Ð³Ð´Ðµ Ð¿ÑÐ¾ÑÐ¾Ð´Ð¸Ð»Ð¸ ÐÐ»Ð¸Ð¼Ð¿Ð¸Ð¹ÑÐºÐ¸Ðµ Ð¸Ð³ÑÑ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾ÑÑÐ¸. ÐÐ°Ð½Ð½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¾ÑÑÑÐµÑÑÐ²Ð»ÑÐ»ÑÑ Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÑÑÐ°ÑÐ¸ÑÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¸ Ð°Ð½Ð°Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¼ÐµÑÐ¾Ð´Ð¾Ð². Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð±ÑÐ»Ð¾ Ð²ÑÑÐ²Ð»ÐµÐ½Ð¾, ÑÑÐ¾ Ð´Ð»Ñ Ð´Ð¾ÑÑÐ¸Ð¶ÐµÐ½Ð¸Ñ Ð¼Ð°ÐºÑÐ¸Ð¼Ð°Ð»ÑÐ½Ð¾ ÑÑÑÐµÐºÑÐ¸Ð²Ð½ÑÑ Ð¿Ð¾Ð»Ð¾Ð¶Ð¸ÑÐµÐ»ÑÐ½ÑÑ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² Ð¿Ð¾ÑÐ»Ðµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ ÐÐ³Ñ, Ð¿ÑÐ¸Ð½Ð¸Ð¼Ð°ÑÑÐ¸Ðµ Ð³Ð¾ÑÐ¾Ð´Ð° Ð´Ð¾Ð»Ð¶Ð½Ñ Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð°ÑÑ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ Ð½Ð°ÑÐ»ÐµÐ´Ð¸Ñ Ð² Ð´Ð¾Ð»Ð³Ð¾ÑÑÐ¾ÑÐ½Ð¾Ð¹ Ð¿ÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ðµ.
description: The aim of the study is the analysis, which made it possible to form criteria (indicators) of the assessing of the contribution of the Olympic Games heritage to the social and economic development of the territories where the modern Olympic Games were held. This analysis was carried out with the use of statistical and analytical methods. As a result it was revealed that in order to achieve the most effective positive results after holding the Olympic Games, host cities should plan the implementation of the heritage in the long-term perspective.
Curiosity ha bisogno di un gommista
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2017

Il rover della Nasa è ancora in salute e continua a studiare Marte. Ma il percorso è arduo e pieno di rischi, soprattutto a causa delle taglienti rocce disseminate sul pianeta. Già in passato gli ingegneri avevano riscontrato dei danni
The family as a rehabilitation resource : the assessment and application of family strengths and weaknesses in the rehabilitation of male arthritic patients: Canadian Arthritis and Rheumatism Society (B.C. Division), Medical Centre, 1955-58
Creators: name: Hagerman, Goldie Jeune
Publisher: name: University of British Columbia
Year: 2012

description: Physical disability resulting from arthritis is a widespread problem: when the sufferer is the breadwinner of a family, it is particularly serious, creating the need for special services not only for the disabled person, but also for his family. But the treatment potential of the patient also depends on how far his family is in turn a source of strength or weakness to him. This is a casework "dimension" that is far from fully explored. This thesis considers the family as a treatment resource in the rehabilitation of a group of male arthritic breadwinners who have been in-patients at the Canadian Arthritis and Rheumatism Society (B.C. Division) Medical centre in Vancouver, B. C, for at least three months. While focusing on the patient in his family group, the study undertakes an intensive examination of the material found in case records and related correspondence from the Medical Centre's Social Service Department, a clinical social work setting. The outcome of the exploration was to emphasize two approaches: (a) the recognition of factors in family behaviour toward the patient which connote family strength, and (b) their application in casework to help meet the patient's needs. Four comparative cases (two each of "strong" and "weak" examples) were selected to identify the variables affecting employment, treatment, and family interaction. The results of this analysis were then applied to the process of diagnosis and treatment to the total cases (seven) for which clinical and social information was available. The specific findings are (1) that the patient's family could influence positively the patient's rehabilitation potential; (2) that family strength could be recognized in a clinical setting treating the patient; (3) that certain additional kinds of diagnostic information are required prior to the patient's admission to the Medical Centre for treatment. A rating scale of family strength can be envisaged as an experimental counterpart of this complex adjustment process. Some practical implications for future service are discussed.
Galassie come tubi fluorescenti
Creators: Stefano Parisini
Publisher: name: Media Inaf
Year: 2017

Non si tratta solo di sapere quanta radiazione ultravioletta è necessaria per arrestare lo sviluppo delle galassie di piccola massa, ma di comprendere come l’universo possa regolare la propria temperatura. Lo afferma a Media Inaf Michele Fumagalli della Durham University, capofila di uno studio che ha utilizzato la luminescenza rossastra provocata dai raggi UV attorno a una galassia campione per misurare la sfuggente radiazione di fondo ultravioletta
NLP-SIR: A Natural Language Approach for Spreadsheet Information Retrieval
Creators: name: Flood, Derek
name: Daid, Kevin Mc
name: Caffery, Fergal Mc
Publisher: name: arXiv
Year: 2009
Subjects: subject: Software Engineering (cs.SE)
subject: Human-Computer Interaction (cs.HC)
subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: Spreadsheets are a ubiquitous software tool, used for a wide variety of tasks such as financial modelling, statistical analysis and inventory management. Extracting meaningful information from such data can be a difficult task, especially for novice users unfamiliar with the advanced data processing features of many spreadsheet applications. We believe that through the use of Natural Language Processing (NLP) techniques this task can be made considerably easier. This paper introduces NLP-SIR, a Natural language interface for spreadsheet information retrieval. The results of a recent evaluation which compared NLP-SIR with existing Information retrieval tools are also outlined. This evaluation has shown that NLP-SIR is a more effective method of spreadsheet information retrieval.
description: 12 Pages, 2 Colour Figures, 3 Tables
title: ÐÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½ÑÑ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ð¹ Ð² ÑÑÐµÑÐµ Ð±Ð»Ð°Ð³Ð¾ÑÐ²Ð¾ÑÐ¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ£ Â«ÐÐ¾Ð´ÑÐ¾ÑÑÐºÐ¾Ð²Ð¾-Ð¼Ð¾Ð»Ð¾Ð´ÐµÐ¶Ð½ÑÐ¹ ÑÐµÐ½ÑÑ ÐÑ ÑÐ°Â»)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ¾Ð»ÑÐ°ÐºÐ¾Ð², ÐÐ°Ð´Ð¸Ð¼
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð±Ð»Ð°Ð³Ð¾ÑÐ²Ð¾ÑÐ¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÑ
Ð±Ð»Ð°Ð³Ð¾ÑÐ²Ð¾ÑÐ¸ÑÐµÐ»ÑÐ½ÑÐµ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ
ÑÐ¿Ð¾Ð½ÑÐ¾ÑÑÑÐ²Ð¾
PR-Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÑ

description: Ð Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ð¾ Ð¿Ð¾Ð½ÑÑÐ¸Ðµ ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½ÑÐµ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ, Ð¿ÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð° Ð¸Ñ ÑÑÑÐ½Ð¾ÑÑÑ Ð² Ð±Ð»Ð°Ð³Ð¾ÑÐ²Ð¾ÑÐ¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸. ÐÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð° Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÑ ÐÐÐ£ ÐÐÐ¦ Â«ÐÑÑÐ°Â» ÐÐ Â«ÐÐ²Ð°Ð´ÑÐ°ÑÂ», Ð¸Ð·ÑÑÐµÐ½Ñ ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½ÑÐµ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð² ÑÑÐµÑÐµ Ð±Ð»Ð°Ð³Ð¾ÑÐ²Ð¾ÑÐ¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ ÑÐ»ÑÑÑÐµÐ½Ð¸Ñ Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð¼ÑÑ ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½ÑÑ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ð¹ Ð² ÐÐ Â«ÐÐ²Ð°Ð´ÑÐ°ÑÂ».
Suppression or enhancement of the Fulde-Ferrell-Larkin-Ovchinnikov order in a one-dimensional optical lattice with particle correlated tunnelling
Creators: name: Wang, B.
name: Duan, L. -M.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Quantum Physics (quant-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study through controlled numerical simulation the ground state properties of spin-polarized strongly interacting fermi gas in an anisotropic optical lattice, which is described by an effective one-dimensional general Hubbard model with particle correlated hopping rate. We show that the Fulde-Ferrell-Larkin-Ovchinnikov (FFLO) type of state, while enhanced by a negative correlated hopping rate, can be completely suppressed by positive particle correlated hopping, yielding to an unusual magnetic phase even for particles with on-site attractive interaction We also find several different phase separation patterns for these atoms in an inhomogeneous harmonic trap, depending on the correlated hopping rate.
Polyethylene glycol complexed with boronophenylalanine as a potential alternative to fructose-boronophenylalanine complexation to increase cellular uptake for BNCT treatment
Creators: name: Qin, Yaxin
name: Dai, Qi
name: Zhang, Zhicheng
name: Sun, Xiaoyan
name: Jiang, Ruolin
name: Bao, Xiaoyan
name: Wu, Linjie
name: Tan, Xin
name: Ying, Xufang
name: Ben, Zhiqing
name: Wei, Qichun
name: Han, Min
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: Boron Neutron Capture Therapy (BNCT) is a novel precision radiotherapy. The key to BNCT application lies in the effective targeting and retention of the boron-10 (10B) carrier. Among the various compounds studied in clinical settings, 4-boronophenylalanine (BPA) become the most prevalent one currently. However, challenges such as inadequate solubility and restricted tumor accumulation have affected the clinical efficacy of treatment with BPA. Therefore, there is an urgent need to prepare formulations with higher tumor uptake efficiency and increased intratumoral accumulation. polyethylene glycol 400 and BPA were added to methanol and stirred until completely dissolved. The solution was then evaporated to remove methanol, yielding a pale-yellow clear liquid of the PEG400-BPA complex. This complex was then used for in vitro and in vivo experiments, and it was evaluated for inhibition effects after BNCT irradiation in GL261 cells. Compared to the clinically used fructose-BPA, PEG400-BPA increased the boron uptake in tumor cells nearly twice and exhibited a better tumor-to-normal tissue ratio (T/N) in the in vivo studies. Due to the BNCT efficacy with PEG400-BPA through in vitro experiments, the PEG400-BPA group also had showed significant cell-killing effects. We discovered that PEG400 can form a complex with BPA, significantly improving its water solubility. It provides a simple, long-term stable, easily convertible, and injectable formulation method for the delivery of BPA in BNCT treatment. It also offers new insights for BPA solubilization and formulation as well as compound forms of administration of boron drugs on the delivery of boron drugs in BNCT. The preparation process of PEG400-BPA and its role in increasing intratumoral boron uptake in cytologic and in vivo experiments (created with BioRender.com)
Quantum oscillations in the parent pnictide BaFe$_2$As$_2$ : itinerant electrons in the reconstructed state
Creators: name: Analytis, James G.
name: McDonald, Ross D.
name: Chu, Jiun-Haw
name: Riggs, Scott C.
name: Bangura, Alimamy F.
name: Kucharczyk, Chris
name: Johannes, Michelle
name: Fisher, I. R.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report quantum oscillation measurements that enable the direct observation of the Fermi surface of the low temperature ground state of \ba122. From these measurements we characterize the low energy excitations, revealing that the Fermi surface is reconstructed in the antiferromagnetic state, but leaving itinerant electrons in its wake. The present measurements are consistent with a conventional band folding picture of the antiferromagnetic ground state, placing important limits on the topology and size of the Fermi surface.
description: 5 pages, 3 figures
A Random Matrix Approach to VARMA Processes
Creators: name: Burda, Zdzisław
name: Jarosz, Andrzej
name: Nowak, Maciej A.
name: Snarska, Małgorzata
Publisher: name: arXiv
Year: 2010
Subjects: subject: Statistical Finance (q-fin.ST)
subject: FOS: Economics and business

description: We apply random matrix theory to derive spectral density of large sample covariance matrices generated by multivariate VMA(q), VAR(q) and VARMA(q1,q2) processes. In particular, we consider a limit where the number of random variables N and the number of consecutive time measurements T are large but the ratio N/T is fixed. In this regime the underlying random matrices are asymptotically equivalent to Free Random Variables (FRV). We apply the FRV calculus to calculate the eigenvalue density of the sample covariance for several VARMA-type processes. We explicitly solve the VARMA(1,1) case and demonstrate a perfect agreement between the analytical result and the spectra obtained by Monte Carlo simulations. The proposed method is purely algebraic and can be easily generalized to q1>1 and q2>1.
description: 16 pages, 6 figures, submitted to New Journal of Physics
Mapping evidence on the effects of gender-affirming hormone therapy on the hard and soft tissues of the craniofacial complex in transgender people: a protocol for a scoping review
Creators: name: Meursinge Reynders, Reint
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Life Sciences

description: This manuscript presents a protocol for a scoping review to systematically map the available evidence on the effects of gender-affirming therapy on the hard and soft tissues of the craniofacial complex in transgender people.
Andreas Khol / Stefan Karner / Wolfgang Sobotka / Bettina Rausch / Günther Ofner / Dietmar Halper (Hrsg.) (2019): Österreichisches Jahrbuch für Politik 2018
Creators: name: Marx, Stefan
Publisher: name: Österreichische Zeitschrift für Politikwissenschaft
Year: 2020

description: n/a
description: Österreichische Zeitschrift für Politikwissenschaft, Bd. 48 Nr. 4 (2019): Offenes Heft
FAIR for cohort studies
Creators: name: Jetten, Mijke
Publisher: name: Zenodo
Year: 2022
Subjects: FAIR data
Data stewardship
Training & capacity building
Data stewards

description: Slide deck for the presentation by Mijke Jetten (Health-RI/DTL) on "FAIR cohort data", for the DORP (Dutch Oncology Research Platform) work conference, 17 Nov 2022
Nelle spire del buco nero
Creators: Redazione Media Inaf
Publisher: name: Media Inaf
Year: 2017

Grazie a osservazioni in ottico, ultravioletto e X compiute con il telescopio spaziale Swift, un team di astrofisici è riuscito a ricostruire la dinamica e le regioni di provenienza delle emissioni generate dall’evento di distruzione mareale Asassn-14li. Lo studio su ApJ Letters
Formulate a concentrated highly branched poly(β-amino ester)/DNA polyplex - one step closer to application in lung cystic fibrosis disease
Creators: name: Qiu, Bei
name: Li, Yinghao
name: He, Zhonglei
name: Li, Zishan
name: Terreau, Sébastien
name: Wang, Xianqing
name: Lyu, Jing
name: Wang, Wenxin
name: Lara-Sáez, Irene
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Astronomical and Space Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Highly branched poly(β-amino ester) (HPAEs)-based gene therapy holds promise for treating lung cystic fibrosis (CF). However, the translation of HPAEs/DNA nanoparticles into clinical applications poses a significant challenge due to the requirement for high concentrations of the formulation. In this work, a straightforward and scalable concentration method was developed for concentrating HPAEs/DNA polyplexes. A series of different buffers with various pH values and ionic components were initially tested to develop the optimized HPAEs/DNA polyplex formulation. Subsequently, the optimized HPAEs/DNA polyplex formulation was concentrated through lyophilization and ultrafiltration. The ultrafiltration outperformed the lyophilization in concentration capacity, showing a 24-fold increase in the concentrated formulation compared to the original non-concentrated formulation. The concentration does not disturb the transfection efficiency in lung CF epithelial cells, indicating its potential for lung delivery applications. Moreover, the concentrated HPAEs/DNA polyplex successfully restored the production of cystic fibrosis transmembrane conductance regulator (CFTR) protein in primary lung CF epithelial cells, surpassing the performance of the non-concentrated common gene transfection reagents such as Lipofectamine 3000 and Xfect. The concentrated HPAEs/DNA formulation represents a promising step forward for preclinical testing (e.g., in vivo evaluation), with further research needed to confirm its potential for clinical use. The processes of concentrating HPAEs/DNA polyplexes.
title: СИОНИСТСКАЯ АРХИТЕКТУРА ПЕРВЫХ ДВУХ ДЕСЯТИЛЕТИЙ XX ВЕКА: ОТ ОРИЕНТАЛИЗМА К ОКСИДЕНТАЛИЗМУ
Creators: name: Ружанский, Владимир
Publisher: name: Новгородский государственный университет имени Ярослава Мудрого (НовГУ)
Year: 2021

description: Статья посвящена ранней истории первого в подмандатной Палестине ивритского города – Тель-Авива. Генезис этого города пришёлся на короткий период времени в истории сионистского движения, когда среди лидеров еврейского ишува (анклава) было популярно ориенталистское направление. Наиболее известным представителем этого направления в философии был Мартин Бубер. В архитектуре Тель-Авива ориентализм нашёл своё выражение в стиле «эрец исраэль», сочетавшем в себе арабскую традицию, мавританское или псевдовосточное направление в европейской архитектуре XIX века и представления архитекторов-сионистов о том, как выглядел Первый храм. В статье подробно описываются и анализируются факторы, определившие судьбу не только архитектурного стиля «эрец исраэль», но и дальнейшее развитие первого в Эрец Исраэль ивритского города.
Enhancement of charged macromolecule capture by nanopores in a salt gradient
Creators: name: Chou, Tom
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Chemical Physics (physics.chem-ph)
subject: Biomolecules (q-bio.BM)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Nanopores spanning synthetic membranes have been used as key components in proof-of-principle nanofluidic applications, particularly those involving manipulation of biomolecules or sequencing of DNA. The only practical way of manipulating charged macromolecules near nanopores is through a voltage difference applied across the nanopore-spanning membrane. However, recent experiments have shown that salt concentration gradients applied across nanopores can also dramatically enhance charged particle capture from a low concentration reservoir of charged molecules at one end of the nanopore. This puzzling effect has hitherto eluded a physically consistent theoretical explanation. Here, we propose an electrokinetic mechanism of this enhanced capture that relies on the electrostatic potential near the pore mouth. For long pores with diameter much greater than the local screening length, we obtain accurate analytic expressions showing how salt gradients control the local conductivity which can lead to increased local electrostatic potentials and charged analyte capture rates. We also find that the attractive electrostatic potential may be balanced by an outward, repulsive electroosmotic flow (EOF) that can in certain cases conspire with the salt gradient to further enhance the analyte capture rate.
description: 10 pages, 6 Figures
AQbD integrated High-Performance Thin Layer Chromatographic Method for Quantitative Estimation of Tavaborole in the presence of its degradants and the matrix of nanostructured lipid carriers.
Creators: name: Patel, Rashmin
name: Neel, Savaliya
name: Mrunali, Patel
name: Patel, Yash
name: Dave, Richa
name: Vikas, Agrawal
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Tavaborole (TAV), a benzoxaborole derivative, is an FDA-approved antifungal agent for treating onychomycosis, a common and persistent fungal infection of the toenails. This study aimed to develop a robust stability-indicating HPTLC method to determine TAV in nanostructured lipid carriers (NLC) using a comprehensive approach that includes risk assessment, and Analytical Quality by Design. The critical method parameters influencing the HPTLC results were screened using a Placket-Burman screening design followed by its optimization using a central composite optimization design. The developed method was validated as per ICH recommendation. Optimized method utilized pre-coated aluminum-backed HPTLC plates using 10 µL/band injection volume, and the plate was developed using an isocratic mobile phase consisting of toluene: ethyl acetate: formic acid (75:25:1%v/v/v) in twin trough chamber pre-saturated for 20 mins with vapors of 10 mL of mobile phase. The separated components were detected at a wavelength of 221 nm. The developed HPTLC method resulted in a retardation factor of 0.49 ± 0.04 for TAV. Validation results revealed the HPTLC method’s specificity (peak purity ≥ 0.999), linearity over a concentration range of 2–10 μg/band, sensitivity (LOD 0.209 μg and LOQ 0.635 μg), accuracy (99.68 - 101.43%w/w), and precision (%RSD < 2.0). The developed robust stability-indicating HPTLC method was successfully implemented for the sustainable testing of the TAV in the NLC formulations and stability testing.
Polyethylene glycol complexed with boronophenylalanine as a potential alternative to fructose-boronophenylalanine complexation to increase cellular uptake for BNCT Treatment
Creators: name: Qin, Yaxin
name: Dai, Qi
name: Zhang, Zhicheng
name: Sun, Xiaoyan
name: Jiang, Ruolin
name: Bao, Xiaoyan
name: Wu, Linjie
name: Tan, Xin
name: Ying, Xufang
name: Ben, Zhiqing
name: Wei, Qichun
name: Han, Min
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: Boron Neutron Capture Therapy (BNCT) is a novel precision radiotherapy. The key to BNCT application lies in the effective targeting and retention of the boron-10 (10B) carrier. Among the various compounds studied in clinical settings, 4-boronophenylalanine (BPA) become the most prevalent one currently. However, challenges such as inadequate solubility and restricted tumor accumulation have affected the clinical efficacy of treatment with BPA. Therefore, there is an urgent need to prepare formulations with higher tumor uptake efficiency and increased intratumoral accumulation. polyethylene glycol 400 and BPA were added to methanol and stirred until completely dissolved. The solution was then evaporated to remove methanol, yielding a pale-yellow clear liquid of PEG400-BPA complex. This complex was then used for in vitro and in vivo experiments, and it was evaluated for inhibition effects after BNCT irradiation in GL261 cells. Compared to the clinically used fructose-BPA, PEG400-BPA increased the boron uptake in tumor cells nearly twice and exhibit a better tumor-to-normal tissue ratio (T/N) in the in vivo studies. Due to the BNCT efficacy with PEG400-BPA through in vitro experiments, PEG400-BPA group also had showed significant cell-killing effects. We discovered that PEG400 can form a complex with BPA, significantly improving its water solubility. It provides a simple, long-term stable, easily convertible, and injectable formulation method for the delivery of BPA in BNCT treatment. It also offers new insights for BPA solubilization and formulation as well as compound forms of administration of boron drugs on the delivery of boron drugs in BNCT. Preparation process of PEG400-BPA and its role in increasing intratumoral boron uptake in cytologic and in vivo experiments (created with BioRender.com)