cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Motion-from-Blur: 3D Shape and Motion Estimation of Motion-blurred Objects in Videos
Creators: name: Rozumnyi, Denys
name: Oswald, Martin R.
name: Ferrari, Vittorio
name: Pollefeys, Marc
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Artificial Intelligence (cs.AI)
subject: Graphics (cs.GR)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: We propose a method for jointly estimating the 3D motion, 3D shape, and appearance of highly motion-blurred objects from a video. To this end, we model the blurred appearance of a fast moving object in a generative fashion by parametrizing its 3D position, rotation, velocity, acceleration, bounces, shape, and texture over the duration of a predefined time window spanning multiple frames. Using differentiable rendering, we are able to estimate all parameters by minimizing the pixel-wise reprojection error to the input video via backpropagating through a rendering pipeline that accounts for motion blur by averaging the graphics output over short time intervals. For that purpose, we also estimate the camera exposure gap time within the same optimization. To account for abrupt motion changes like bounces, we model the motion trajectory as a piece-wise polynomial, and we are able to estimate the specific time of the bounce at sub-frame accuracy. Experiments on established benchmark datasets demonstrate that our method outperforms previous methods for fast moving object deblurring and 3D reconstruction.
description: CVPR 2022 camera-ready
Synthesis of Potential Impurities of Dabigatran Etexilate
Creators: name: U. Rajasekhar Reddy
name: B. Sreenivasulu
name: D. Satheesh
name: Sundaram, Dhanraj T. S. S.
name: G. Srikanth
name: S. Paul Douglas
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology

description: The present work describes the origin, control and synthesis of two potent impurities of dabigatran etexilate 1, dabigatran dimer 2 and dabigatran n-propyl ester 3 from the commercially available raw materials 2-[(4-Cyanophenyl)amino]acetic acid (4) and N-[3-Amino-4-(methylamino)benzoyl]-N-2-pyridinyl-β-alanine ethyl ester (5). These impurities are the process related impurities and may affect the quality of drug substance, during its manufacturing in large scale. These impurities are not only the crucial components in determining the quality and safety of the drug substance 1 but also provide a better understanding of impurity profiling.
Character Attribute Extraction from Movie Scripts using LLMs
Publisher: name: IEEE Signal Processing Society
Year: 2024

description: Narrative understanding is an integrative task of studying characters, plots, events, and relations in a story. 
It involves natural language processing tasks such as named entity recognition and coreference resolution to identify the characters, semantic role labeling and argument mining to find character actions and events, information extraction and question answering to describe character attributes, causal analysis to relate different events, and summarization to find the main storyline. 
In this work, we aim to formally operationalize the task of character attribute extraction, motivated by analyzing inclusive character representations and portrayals. 
We focus on a mix of static and dynamic attribute types that require varying context sizes for their accurate retrieval. 
We use automated screenplay parsing, entity recognition, and external knowledge bases to collect character descriptions from movie scripts and explore different prompting strategies (zero-shot, few-shot, and chain-of-thought) to leverage large language models for attribute extraction.
Acute optogenetic stimulation of serotonin neurons reduces cell proliferation in the dentate gyrus of mice
Creators: name: Araragi, Naozumi
name: Petermann, Markus
name: Suzuki, Mototaka
name: Larkum, Matthew
name: Mosienko, Valentina
name: Bader, Michael
name: Alenina, Natalia
name: Klempin, Friederike Claudia
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2025
Subjects: subject: 615

description: The dentate gyrus of the hippocampus is targeted by axons from serotonin raphe neurons, where the neurotransmitter modulates adult neurogenesis and antidepressant action, and mediates the neurogenic effect of running. Whether running-induced cell proliferation is directly mediated by serotonin remains unknown. Here, we took advantage of Tph2-ChR2-YFP transgenic mice in which the light-sensitive protein channelrhodopsin-2 (ChR2) is specifically expressed in tryptophan hydroxylase 2 (TPH2)-expressing neurons. We selectively activated serotonin neurons via optogenetics and determined the effect on cell proliferation in the dentate gyrus. Our data reveal a significant reduction in the number of newly generated cells upon overnight raphe stimulation. The decrease in cell proliferation was absent when serotonin neurons were light-activated for six consecutive nights. However, we observed an interhemispheric difference in BrdU-positive cell numbers. We conclude that acute network dynamics occur between serotonin raphe neurons and the hippocampus, directly affecting precursor cell proliferation.
Influence of Salt and Surfactant on Copper Removal by Xanthan Gum-G-itaconic Acid/Bentonite Hydrogel Composite From Water Using Fractional Factorial Design
Creators: name: Koohi, Ahmad Dadvand
name: Nasimi, Fatemeh
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Hematology

description: A novel xanthan gum-g-itaconic acid/bentonite (XG-g-PIA/BET) hydrogel composite was synthesized using free radical polymerization in the presence of ammonium persulfate as initiator and N,N’-methylenebis(acrylamide) as crosslinker. The Fourier transform infrared spectroscopy spectra of XG-g-PIA/BET composite before and after adsorption gave strong evidence of the successful adsorbance of copper ions with COOH groups. Influence of the presence of three typical salts (NaCl, CaCl2, and FeCl3), and three types of surfactants including anionic (Brij 35), cationic (N-Cetyl-N,N,N-trimethyl ammonium bromide), anionic (sodium dodecyl sulfate), and their two-term interactions on copper ions adsorption capacity were investigated using 32 experiments with fractional factorial experimental design. The analysis of variance (ANOVA) showed that the fitted model had a significant P-value (<0.0001), and except FeCl3, all other variables present in the aqueous solution increased the copper adsorption capacity. In addition, there was no significant two-term interaction between different variables.
Fish habitat and fisheries of Brahmaputra River in Assam, India
Creators: name: B. K. Bhattacharjya
name: U. Bhaumik
name: A. P. Sharma
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: River Brahmaputra is a trans-boundary major river flowing through the northeastern state of Assam, India and is the lifeline of its natural fisheries. In the present article, we discuss eco-hydrobiology (including sediment quality and energy flow) of River Brahmaputra and its important tributaries in the state of Assam, India based on extensive synoptic studies conducted from April 1996 to March 1998, duly collated with past and present studies. Salient aspects of fisheries of the river system in the state (ichthyofauna, biogeography, conservation status, migratory and exotic fish species, trends in fish yield and species composition, fishing crafts and gear) are discussed in light of past and present studies conducted by the Indian Council of Agricultural Research-Central Indian Fisheries Research Institute and others. Fisheries of floodplain wetlands (beels) located in the Brahmaputra valley in the state and their interaction with the river system are also discussed.
Modélisation du fluage propre du béton sous température et contrainte élevées
Creators: name: Torrenti, Jean-Michel
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: Les centrales nucléaires françaises sont constituées pour la génération précédant l’EPR en deux enceintes de confinement concentriques. L’enceinte interne, précontrainte bi-axialement, a une épaisseur comprise entre 80 et 120cm et est dimensionnée pour résister en cas d’accident grave à une température élevée (180°C pendant 2 semaines) et une surpression de 0,5 MPa. A cause de cette surpression, si la précontrainte n’est pas suffisante, des contraintes de traction peuvent apparaître dans la structure. Et à cause de l’élévation de température, l’évolution du fluage du béton est accélérée. La modélisation de ces phénomènes couplés est très importante pour la sécurité de ces structures (notamment de l’étanchéité de l’enceinte interne).Ici nous présentons un modèle de fluage propre qui considère les éléments suivants : - le fluage propre suit une loi logarithmique par rapport à la durée du chargement. Sa cinétique est affectée par l’élévation de température au moyen d’une relation de type Arrhenius qui exprime la thermo-activation, - un endommagement dû à l’élévation de température est pris en compte], - un couplage est également introduit entre le fluage et l’endommagement par le biais de l’évolution de l’endommagement qui dépend de la déformation de fluage. Le modèle est enfin comparé aux résultats expérimentaux. Ce travail a été effectué dans le cadre du projet MACENA.
description: Academic Journal of Civil Engineering, Vol 34 No 1 (2016): Special Issue - RUGC 2016 Liège
River ecosystems of the Central Highland ecoregion: Spatial distribution of benthic flora and fauna in the Plateau rivers (tributaries of the Yamuna and Ganga) in Central India
Creators: name: Nautiyal, Prakash
name: Asheesh Shivam Mishra
name: Verma, Jyoti
name: Agrawal, Asha
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology

description: This study reveals the relationship of biotic assemblages to their environments in the Central Highland Ecoregion rivers (Ken, Paisuni and Tons). Such knowledge will enhance our predictive abilities in the ecological studies and resource management in the concerned region. Rivers of an ecoregion are expected to harbour similar flora, fauna, and communities. This hypothesis was examined by tracking the spatial variation in richness, density, and taxonomic composition of benthic diatom and macroinvertebrate assemblages in three Plateau rivers whose course lay within 3°N latitude. Taxonomic richness and density decreased with the reduction of substrate size from the headwaters to the lowlands. Cluster and ordination analyses indicate prevalence of intrabasin rather than interbasin gradients of abundance. In both assemblages, the most abundant taxon is rarely similar longitudinally or across the river sections in the ecoregion. Hence, proximate factors govern the assemblages rather than ecoregional properties (latitude, altitude). This, and the high richness of diatom flora, points to diverse assemblages from the headwater to the lowland section in each river and among the rivers of the ecoregion.
CryoCiM: Cryogenic Compute-in-Memory based on the Quantum Anomalous Hall Effect
Creators: name: Alam, Shamiul
name: Islam, Md Mazharul
name: Hossain, Md Shafayat
name: Jaiswal, Akhilesh
name: Aziz, Ahmedullah
Publisher: name: arXiv
Year: 2021
Subjects: subject: Emerging Technologies (cs.ET)
subject: FOS: Computer and information sciences

description: The scaling of the already-matured CMOS technology is steadily approaching its physical limit, motivating the quest for a suitable alternative. Cryogenic operation offers a promising pathway towards continued improvement in computing speed and energy efficiency without aggressive scaling. However, the memory wall bottleneck of the traditional von-Neumann architecture persists even at cryogenic temperature. That is where a compute-in-memory (CiM) architecture, that embeds computing within the memory unit, comes into play. Computations within the memory unit help reduce the expensive data transfer between the memory and the computing units. Therefore, CiM provides extreme energy efficiency that can enable lower cooling cost at cryogenic temperature. In this work, we demonstrate CryoCiM, a cryogenic compute-in-memory framework utilizing a non-volatile memory system based on the quantum anomalous Hall effect (QAHE). Our design can perform memory read/write, and universal binary logic operations (NAND, NOR, and XOR). We design a novel peripheral circuit assembly that can perform the read/write, and single-cycle in-memory logic operations. The utilization of a QAHE-based memory system promises robustness against process variations, through the usage of topologically protected resistive states for data storage. CryoCiM is the first step towards utilizing exclusively cryogenic phenomena to serve the dual purpose of storage and computation with ultra-low power (nano-watts) operations.
description: 13 pages, 6figures
title: SotA – Cloud Resource & Cost Management Tools (ResCo)
title: Ein technischer Überblick über Open Source, SaaS und Plattformlösungen
titleType: Subtitle
Creators: name: Burkhardt, Detlef
Publisher: name: Zenodo
Year: 2025
Subjects: subject: cloud
subject: Cloud Computing
subject: cloud-computing
subject: finops
subject: greentech
subject: devops
subject: infrastructure-as-code
subject: kubecost
subject: open source
subject: cloud resource analysis
subject: sustainability
subject: infrastructure visibility

description: Cloud-Kosten zu reduzieren heißt meistens auch: CO₂ einzusparen. Wer seine Infrastruktur besser versteht, spart nicht nur Geld, sondern auch Energie. Das ist vermutlich eine der günstigsten Möglichkeiten, mit Technologie Verantwortung zu übernehmen; für den eigenen Haushalt und für den Planeten.

Dieses Working Paper bietet eine strukturierte Übersicht zum aktuellen Stand der Technik (State-of-the-Art) im Bereich Cloud Resource und Cost Management. Es vergleicht über 15 Tools in drei Gruppen (Open Source mit OnPrem-Option, reine SaaS-Angebote und cloudnative Plattformlösungen) anhand von mehr als 30 Attributen. Ziel ist es, eine praxisnahe Grundlage für Tool-Auswahl, Strategieentwicklung und FinOps-Prozesse bereitzustellen.
Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway
Creators: name: Lv, Hongjun
name: Liu, Rui
name: Yang, Qi
name: Shi, Jing
name: Chen, Pu
name: Ji, Meiju
name: Shi, Bingyin
name: Hou, Peng
name: Fu, Jiao
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Infectious Diseases
subject: FOS: Health sciences
subject: Cancer
subject: Developmental Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: Periostin is usually considered as an oncogene in diverse human cancers, including breast, prostate, colon, esophagus, and pancreas cancers, whereas it acts as a tumor suppressor in bladder cancer. In gastric cancer, it has been demonstrated that periglandular periostin expression is decreased whereas stromal periostin expression is significantly increased as compared with normal gastric tissues. Moreover, periostin produced by stromal myofibroblasts markedly promotes gastric cancer cell growth. These observations suggest that periostin derived from different types of cells may play distinct biological roles in gastric tumorigenesis. The aim of this study was to explore the biological functions and related molecular mechanisms of epithelial cell-derived periostin in gastric cancer. Our data showed that periglandular periostin was significantly down-regulated in gastric cancer tissues as compared with matched normal gastric mucosa. In addition, its expression in metastatic lymph nodes was significantly lower than that in their primary cancer tissues. Our data also demonstrated that periglandular periostin expression was negatively associated with tumor stage. More importantly, restoration of periostin expression in gastric cancer cells dramatically suppressed cell growth and invasiveness. Elucidation of the mechanisms involved revealed that periostin restoration enhanced Rb phosphorylation and sequentially activated the transcription of E2F1 target gene p14ARF, leading to Mdm2 inactivation and the stabilization of p53 and E-cadherin proteins. Strikingly, these effects of periostin were abolished upon Rb deletion. Collectively, we have for the first time demonstrated that epithelial cell-derived periostin exerts tumor-suppressor activities in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway.
Towards Super-Resolution CEST MRI for Visualization of Small Structures
Creators: name: Folle, Lukas
name: Tkotz, Katharian
name: Gadjimuradov, Fasil
name: Kapsner, Lorenz
name: Fabian, Moritz
name: Bickelhaupt, Sebastian
name: Simon, David
name: Kleyer, Arnd
name: Krönke, Gerhard
name: Zaiß, Moritz
name: Nagel, Armin
name: Maier, Andreas
Publisher: name: arXiv
Year: 2021
Subjects: subject: Image and Video Processing (eess.IV)
subject: Artificial Intelligence (cs.AI)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Medical Physics (physics.med-ph)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: The onset of rheumatic diseases such as rheumatoid arthritis is typically subclinical, which results in challenging early detection of the disease. However, characteristic changes in the anatomy can be detected using imaging techniques such as MRI or CT. Modern imaging techniques such as chemical exchange saturation transfer (CEST) MRI drive the hope to improve early detection even further through the imaging of metabolites in the body. To image small structures in the joints of patients, typically one of the first regions where changes due to the disease occur, a high resolution for the CEST MR imaging is necessary. Currently, however, CEST MR suffers from an inherently low resolution due to the underlying physical constraints of the acquisition. In this work we compared established up-sampling techniques to neural network-based super-resolution approaches. We could show, that neural networks are able to learn the mapping from low-resolution to high-resolution unsaturated CEST images considerably better than present methods. On the test set a PSNR of 32.29dB (+10%), a NRMSE of 0.14 (+28%), and a SSIM of 0.85 (+15%) could be achieved using a ResNet neural network, improving the baseline considerably. This work paves the way for the prospective investigation of neural networks for super-resolution CEST MRI and, followingly, might lead to a earlier detection of the onset of rheumatic diseases.
Molecular dynamics of plant-virus interactions : unravelling the dual role of ubiquitin proteasome system
Creators: name: Sharma, Veerendra
name: Devendran, Ragunathan
name: Kumar, Manish
name: Prajapati, Ramgopal
name: Kumar, Ritesh
name: Prakash, Ved
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2025
Subjects: subject: 572

description: Plants response to various biotic and abiotic factors requires not only the de novo synthesis of proteins and enzymes but also their precise and timely degradation. The latter is achieved through protein degradation machinery such as the ubiquitin proteasome pathway (UPS). The UPS plays a central role in maintaining cellular physiology and orchestrating plant response to stresses responses. The UPS regulates all stages of defense response from pathogen perception to mounting defense response, this make the UPS a suitable candidate for host manipulation. Viruses are obligatory intracellular pathogens and master of manipulating host defense machinery for successful infection and spread. Several reports suggest a dynamic interaction between the host UPS machinery and viruses. This review focuses on our current understanding of the involvement of UPS in defense against plant viruses and how viruses have evolved mechanisms to counter and exploit UPS machinery for their advantage.
title: SotA – Cloud Resource & Cost Management Tools (ResCo)
title: Ein technischer Überblick über Open Source, SaaS und Plattformlösungen
titleType: Subtitle
Creators: name: Burkhardt, Detlef
Publisher: name: Zenodo
Year: 2024
Subjects: subject: cloud
subject: Cloud Computing
subject: cloud-computing
subject: finops
subject: greentech
subject: devops
subject: infrastructure-as-code
subject: kubecost
subject: open source
subject: cloud resource analysis
subject: sustainability
subject: infrastructure visibility

description: Cloud-Kosten zu reduzieren heißt meistens auch: CO₂ einzusparen. Wer seine Infrastruktur besser versteht, spart nicht nur Geld, sondern auch Energie. Das ist vermutlich eine der günstigsten Möglichkeiten, mit Technologie Verantwortung zu übernehmen; für den eigenen Haushalt und für den Planeten.

Dieses Working Paper bietet eine strukturierte Übersicht zum aktuellen Stand der Technik (State-of-the-Art) im Bereich Cloud Resource und Cost Management. Es vergleicht über 15 Tools in drei Gruppen (Open Source mit OnPrem-Option, reine SaaS-Angebote und cloudnative Plattformlösungen) anhand von mehr als 30 Attributen. Ziel ist es, eine praxisnahe Grundlage für Tool-Auswahl, Strategieentwicklung und FinOps-Prozesse bereitzustellen.
Lattice QCD Determination of the Bjorken-$x$ Dependence of Parton Distribution Functions at Next-to-next-to-leading Order
Creators: name: Gao, Xiang
name: Hanlon, Andrew D.
name: Mukherjee, Swagato
name: Petreczky, Peter
name: Scior, Philipp
name: Syritsyn, Sergey
name: Zhao, Yong
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We report the first lattice QCD calculation of pion valence quark distribution with next-to-next-to-leading order perturbative matching correction, which is done using two fine lattices with spacings $a=0.04$ fm and $0.06$ fm and valence pion mass $m_π=300$ MeV, at boost momentum as large as $2.42$ GeV. As a crucial step to control the systematics, we renormalize the pion valence quasi distribution in the recently proposed hybrid scheme, which features a Wilson-line mass subtraction at large distances in coordinate space, and develop a procedure to match it to the $\overline{\rm MS}$ scheme. We demonstrate that the renormalization and the perturbative matching in Bjorken-$x$ space yield a reliable determination of the valence quark distribution for $0.03\lesssim x \lesssim 0.80$ with 5-20\% uncertainties.
description: 4 pages, 4 figures and appendix
title: Математическое моделирование в машиностроении
Creators: name: Никитков, Николай
name: Ковеленов, Николай
name: Шабалин, Дмитрий
Publisher: name: ПОЛИТЕХ-ПРЕСС
Year: 2020

description: Соответствует содержанию федеральной дисциплины «Математическое моделирование в машиностроении» по направлению 15.04.05 «Конструкторско-технологическое обеспечение машиностроительных производств». Рассмотрены вопросы назначения моделирования, создания моделей различных процессов машиностроительного производства на микро- и макроуровнях, изучены аналоговые модели и моделирование технологических процессов изготовления деталей, теория надежности и создания статистических моделей для прогнозирования отказов функционирования изделий. Предназначено для студентов высших учебных заведений, обучающихся по направлению подготовки магистров «Конструкторско-технологическое обеспечение машиностроительных производств».
Supplemental Material for the study: Patients with autoimmune liver disease have glucose disturbances that mechanistically differ from steatotic liver disease
Creators: name: Jensen, Anne-Sofie
name: Ytting, Henriette
name: Werge, Mikkel P
name: Rashu, Elias B
name: Hetland, Liv
name: Thing, Mira
name: Nabilou, Puria
name: Burisch, Johan
name: Nyvold Bojsen-Møller, Kirstine
name: Junker, Anders E
name: Hobolth, Lise
name: Mortensen, Christian
name: Tofteng, Flemming
name: Bendtsen, Flemming
name: Møller, Søren
name: Vyberg, Mogens
name: Serizawa, Reza R
name: Gluud, Lise L
name: Wewer Albrechtsen, Nicolai J
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 320209
subject: Gastroenterology and hepatology
classificationCode: 320208
subject: Endocrinology

description: AbstractAutoimmune liver diseases are associated with an increased risk of diabetes, yet the underlying mechanisms remain unknown. In this cross-sectional study, we investigated the glucose-regulatory disturbances in patients with autoimmune hepatitis (AIH, n=19), primary biliary cholangitis (PBC, n=15), and primary sclerosing cholangitis (PSC, n=6). Healthy individuals (n=24) and patients with metabolic dysfunction-associated steatotic liver disease (MASLD, n=18) were included as controls. Blood samples were collected during a 120 min oral glucose tolerance test. We measured the concentrations of glucose, C-peptide, insulin, glucagon, the two incretin hormones glucose insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1). We calculated the homeostasis model assessment of insulin resistance (HOMA-IR), whole body insulin resistance (Matsuda index), insulin clearance, and insulinogenic index. All patient groups had increased fasting plasma glucose and impaired glucose responses compared with healthy controls. Beta-cell secretion was increased in AIH, PBC, and MASLD but not in PSC. AIH and MASLD patients had hyperglucagonemia and hepatic, as well as peripheral, insulin resistance and decreased insulin clearance, resulting in hyperinsulinemia. Patients with autoimmune liver disease had an increased GIP response, and those with AIH or PBC had an increased GLP-1 response. Our data demonstrate that the mechanism underlying glucose disturbances in patients with autoimmune liver disease differs from that underlying MASLD, including compensatory incretin responses in patients with autoimmune liver disease. Our results suggest that glucose disturbances are present at an early stage of the disease.
title: Dominique Mathez, Deborah Paul, Raymond Schinazi, Jacques Leibowitch, "Taux de réplication HIV générés in vitro par des cellules de patients dans des lymphocytes normaux activés et l'évaluation in vitro et ex vivo de l'efficacité des drogues anti-HIV."
Creators: name: Mathez, Dominique
name: Paul, Deborah
name: Schinazi, Raymond F.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Résumé.
description: Source: http://www.calames.abes.fr/pub/ms/Calames-20193111031798157
Digging into Axion Physics with (Baby)IAXO
Creators: name: Dafni, T.
name: Galan, J.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: Dark Matter searches have been ongoing for three decades; the lack of a positive discovery of the main candidate, the WIMP, after dedicated efforts, has put axions and axion-like-particles in the spotlight. The three main techniques employed to search for them complement each other well in covering a wide range in the parameter space defined by the axion decay constant and the axion mass. The International AXion Observatory (IAXO) is an international collaboration planning to build the fourth generation axion helioscope, with an unparalleled expected sensitivity and discovery potential. The distinguishing characteristic of IAXO is that it will feature an axion-specific magnet, with a large axion-sensitive cross-section, and will be equipped with x-ray focusing devices and detectors that have been developed for axion physics. In this paper, we review aspects that motivate IAXO and its prototype, BabyIAXO, in the axion and ALPs landscape. As part of this Special Issue, some emphasis is given on the Spanish participation in the project, of which CAPA is a strong promoter
description: 21 pages, 5 figures. Submitted to Universe
Intrinsic decoherence for the displaced harmonic oscillator
Creators: name: Urzúa, Alejandro R.
name: Moya-Cessa, Héctor M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: By using the complete solution of the Milburn equation (beyond the Lindblad form that it is generally used) that describes intrinsic decoherence, we study the decaying dynamics of a displaced harmonic oscillator. We calculate the expectation values of position quadrature, and the number operator in initial coherent and squeezed states.
Telecom-band Hyperentangled Photon Pairs from a Fiber-based Source
Creators: name: Chen, Changjia
name: Xu, Calvin
name: Riazi, Arash
name: Zhu, Eric Y.
name: Greenwood, Alexander
name: Gladyshev, Alexey V.
name: Kazansky, Peter G.
name: Kirby, Brian T.
name: Qian, Li
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Hyperentanglement, the simultaneous and independent entanglement of quantum particles in multiple degrees of freedom, is a powerful resource that can be harnessed for efficient quantum information processing. In photonic systems, the two degrees of freedom (DoF) often used to carry quantum and classical information are polarization and frequency, thanks to their robustness in transmission, both in free space and in optical fibers. Telecom-band hyperentangled photons generated in optical fibers are of particular interest because they are compatible with existing fiber-optic infrastructure, and can be distributed over fiber networks with minimal loss. Here, we experimentally demonstrate the generation of telecom-band biphotons hyperentangled in both the polarization and frequency DoFs using a periodically-poled silica fiber and observe entanglement concurrences above 0.95 for both polarization and frequency DOFs. Furthermore, by concatenating a Hong-Ou-Mandel interference test for frequency entanglement and full state tomography for polarization entanglement in a single experiment, we can demonstrate simultaneous entanglement in both the polarization and frequency DOFs. The states produced by our hyperentanglement source can enable protocols such as dense coding and high-dimensional quantum key distribution.
Regional Clean Energy Innovation
Creators: name: Surana, Kavita
name: Williams, Ellen D.
name: Krawczyk, Wojciech
name: Montgomery, Michael
name: O'Neill, Jon
name: Thomas, Zachary
name: Zhang, Ying
Publisher: name: Digital Repository at the University of Maryland
Year: 2020
Subjects: energy
innovation
public policy
climate change
regional studies

description: This report provides data-driven approaches and insights for federal and state planning to accelerate clean energy innovation by aligning programs with regional resources and economic development goals.
Quasar continuum spectrum disfavors black holes with a magnetic monopole charge
Creators: name: Banerjee, Indrani
name: Chawan, Vijay Shersingh
name: Mandal, Bhaswati
name: Sahoo, Siddharth Kumar
name: SenGupta, Soumitra
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Black holes carrying a magnetic monopole charge are a subject of interest for a long time. In this work we explore the possibility of an observational evidence of such black holes carrying a magnetic monopole, namely the Bardeen rotating black holes. We derive the theoretical spectrum from the accretion disk surrounding a Bardeen black hole using the thin-disk approximation. We compare the theoretically derived spectrum in comparison to the optical data of eighty Palomar Green quasars to constrain the monopole charge parameter $g$ and the spin parameter $a$ of the quasars. From our analysis we note that the Kerr-scenario in \gr\ is observationally more favored than black holes with a monopole charge. We arrive at such a conclusion using error estimators like $χ^2$, the Nash-Sutcliffe efficiency, the index of agreement and their modified forms. In particular, black holes with $g \geq 0.03$ are outside $99\%$ confidence interval. The implications are discussed.
Method: dependent variables
Creators: name: Gaschler, Robert
name: Blech, Christine
Publisher: name: OSF Registries
Year: 2017

description: a) Time required until solution, b) solution success for the extinction trial: binary variable coding whether the solution has been found (1) or not found (0) after a limit of 180 seconds, c) solution type in the critical trial, i.e. whether the direct solution A – C or the Einstellung solution B – A – 2C is chosen. Main comparisons focus on the indicators for the extinction trial which is presented identically to all experimental conditions. For additional analyses: codings of solution processes in the verbal protocols, e.g., solution attempts starting with “jug B” are coded as Einstellung solution attempts.
Research question on an exploratory base
Creators: name: Gaschler, Robert
name: Blech, Christine
Publisher: name: OSF Registries
Year: 2017

description: We would like to investigate whether thinking aloud or thinking silently affects Einstellung (set) effects in a systematic manner. Since the research literatur gives rise to both assumptions - either increased or decreased Einstellung effects when thinking aloud - we decided in favor of an exploratory study.
Entropy of Hawking Radiation for Two-Sided Hyperscaling Violating Black Branes
Creators: name: Omidi, Farzad
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, we study the von Neumann entropy of Hawking radiation $S_{\rm R}$ for a $d+2$-dimensional Hyperscaling Violating (HV) black brane which is coupled to two Minkowski spacetimes as the thermal baths. We consider two different situations for the matter fields: First, the matter fields are described by a $CFT_{d+2}$ whose central charge $c$ is very large. Second, they are described by a d+2 dimensional HV QFT which has a holographic gravitational theory that is a HV geometry at zero temperature. For both cases, we calculate the Page curve of the Hawking radiation as well as the Page time $t_{\rm Page}$. For the first case, $S_{\rm R}$ grows linearly with time before the Page time and saturates after this time. Moreover, $t_{\rm Page}$ is proportional to $\frac{2 S_{\rm th}}{c T}$, where $S_{\rm th}$ and $T$ are the thermal entropy and temperature of the black brane. For the second case, when the hyperscaling violation exponent $θ_m$ of the matter fields is zero, the results are very similar to those for the first case. However, when $θ_m \neq 0$, the entropy of Hawking radiation grows exponentially before $t_{\rm Page}$ and saturates after this time. Furthermore, the Page time is proportional to $\log \left( \frac{1}{G_{\rm N,r}} \right) $, where $G_{\rm N,r}$ is the renormalized Newton's constant. It was also observed that for both cases, $t_{\rm Page}$ is a decreasing and an increasing function of the dynamical exponent $z$ and hyperscaling violation exponent $θ$ of the black brane geometry, respectively. Moreover, for the second case, $t_{\rm Page}$ is independent of $z_m$, and for $θ_m \neq 0$, it is a decreasing function of $θ_m$.
description: 32 pages, 7 figures, V2: Published version in JHEP
Bath deformations, islands and holographic complexity
Creators: name: Bhattacharya, Aranya
name: Bhattacharyya, Arpan
name: Nandy, Pratik
name: Patra, Ayan K.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Considering a doubly holographic model, we study the evolution of holographic subregion complexity corresponding to deformations of bath state by a relevant scalar operator, which corresponds to a renormalization group flow from the AdS-Schwarzschild to the Kasner universe in the bulk. The subregion complexity shows a discontinuous jump at Page time at a fixed perturbation, where the discontinuity depends solely on the system's parameters. We show that the amount of discontinuity decreases with the perturbation as well as with the scaling dimension of the relevant scalar operator.
description: 27 pages, 7 figures, minor typo corrected and references updated
KGBoost: A Classification-based Knowledge Base Completion Method with Negative Sampling
Creators: name: Wang, Yun-Cheng
name: Ge, Xiou
name: Wang, Bin
name: Kuo, C. -C. Jay
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Knowledge base completion is formulated as a binary classification problem in this work, where an XGBoost binary classifier is trained for each relation using relevant links in knowledge graphs (KGs). The new method, named KGBoost, adopts a modularized design and attempts to find hard negative samples so as to train a powerful classifier for missing link prediction. We conduct experiments on multiple benchmark datasets, and demonstrate that KGBoost outperforms state-of-the-art methods across most datasets. Furthermore, as compared with models trained by end-to-end optimization, KGBoost works well under the low-dimensional setting so as to allow a smaller model size.
Chargements exceptionnels et comportements dynamiques du troisième pont suspendu sur le Bosphore
Creators: name: De Ville De Goyet, V.
name: Duchêne, Y.
name: Coméliau, L.
name: Hérode, M.
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: D’une longueur totale de 2240 m, ce nouveau pont hybride, suspendu-haubané, aura une portée centrale de 1408 m. A l’instar du pont de Brooklyn (New York), la travée principale sera soutenue directement aux pylônes par des haubans d’une part et par des câbles de suspensions principaux avec suspentes verticales d’autre part. Les pylônes en béton atteignent la hauteur de 320 m, tandis que le tablier de 58 mètres de large et de 5,50 m de hauteur supportera deux fois quatre bandes pour le trafic routier international, deux voies de chemin de fer et deux trottoirs latéraux destinés aux piétons. A pont exceptionnel, chargement exceptionnel : 1) situé dans une zone de forte séismicité et au vu de sa longueur, le pont doit être vérifié sous accélérogrammes différentiels en chaque appui 2) un tel ouvrage fait automatiquement l’objet l’études poussées sous les effets du vent déterminés sur base d’analyse de données de stations météos et de nombreux essais en soufflerie afin de vérifier son comportement dynamique sous les rafales de vent et de vérifier toutes les instabilités aérodynamiques qui pourraient se produire tant en service que durant les phases de construction.
description: Academic Journal of Civil Engineering, Vol 34 No 1 (2016): Special Issue - RUGC 2016 Liège
A standardized in vitro bioengineered skin for penetrating wound modeling
Creators: name: Silva, C. Sofia Salazar
name: Petzold, Werner
name: Hirsch, Ulrike
name: Schmelzer, Christian E. H.
name: Friedmann, Andrea
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2025
Subjects: subject: 615

description: Over the years, significant progress has been made in developing cost-effective and ethical in vitro bioengineered skin substitutes to study cutaneous wound healing processes. Rodents and small animal models are not optimal due to physiological differences in their skin compared to human skin. The generation of reproducible and precise wounds is key to obtaining comparable results. We created a three-dimensional skin wounding model by growing a fully differentiated, stratified squamous epithelium from human keratinocytes at an air–liquid interface on a type I collagen scaffold concealed with human dermal BJ fibroblasts. To generate the wounds, a stamp with incorporated needles with a length of 250 µm was used to puncture the epidermis to produce standardized wounds. The stamping needle technique is a practical and inexpensive method for creating length-tailored wounds on three-dimensional skin models. The effectiveness of this technique in treating 3D skin models was demonstrated, accompanied by an evaluation of the model’s functionality in terms of cell proliferation, differentiation, and immunological characteristics.
The implications of the euro crisis for democracy
Creators: name: Kriesi, Hanspeter
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The question of whether European democracy is in crisis is not new, but is posed in a new way in the shadow of the euro crisis. In the tradition of the studies of democratic support and disaffection and based on data from the European Social Survey 2012, this article analyses the conceptions and evaluations of democracy in the different regions of Europe under the impact of the euro crisis. It shows that the perceived poor performance of the economy and of the government in the crisis, indeed, leads citizens across Europe to evaluate the way their national democracy works more critically – especially in the hard hit regions of Central and Eastern Europe and Southern Europe, and in authoritarian countries. However, it also shows that this critical evaluation of democracy does not undermine the citizens’ support for democracy. Quite to the contrary: democratic principles are actually strengthened by the dissatisfaction of the citizens with the economic and political performance of their countries in the crisis.
Linear Bosonic Quantum Field Theories Arising from Causal Variational Principles
Creators: name: Dappiaggi, Claudio
name: Finster, Felix
name: Oppio, Marco
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: It is shown that the linearized fields of causal variational principles give rise to linear bosonic quantum field theories. The properties of these field theories are studied and compared with the axioms of local quantum physics. Distinguished quasi-free states are constructed.
description: 29 pages, LaTeX, 2 figures, minor improvements (published version)
Simulation of the spatial shift in detector response for polarized protons within a calorimeter
Creators: name: Blitstein, Austin
name: Wojtsekhowski, Bogdan
Publisher: name: arXiv
Year: 2021
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Measurement of the helicity dependent elastic electron-proton scattering cross section provides a key means of investigating parity violation within the proton. However, such measurements exhibit potential instrumental effects associated with the detection of polarized recoiled protons. In particular, spin-orbit interactions within a massive detector induce a systematic spatial shift in the detector signal. In this study, we determine the size of this shift using the Geant4 simulation toolkit. For a typical hadron calorimeter, we found a polarization dependent shift on the order of 0.01-0.1 mm, multiple orders of magnitude smaller than the typical spatial resolution seen in hadronic calorimeters. Additionally, we provide the custom modifications required of the Geant4 source code to implement the quasi-elastic scattering of polarized protons incident on nuclei in the detector. The modifications are readily extendable to generic matter sources, and can be used for the study of additional spin dependent observables in Geant4.
description: 11 pages, 6 figures
Whispering-gallery modes promote enhanced optical backflow in a perforated dielectric microsphere
Creators: name: Geints, Yury E.
name: Minin, Igor V.
name: Minin, Oleg V.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences
subject: J.2
subject: 65Z05

description: Optical energy flow inside a dielectric microsphere is usually codirected with the optical wavevector. At the same time, if the optical field in a microsphere is in resonance with one of the high-quality spatial eigenmodes (whispering-gallery modes - WGMs), a region of reverse energy flow emerges in the shadow hemisphere. This area is of considerable practical interest due to increased optical trapping potential. In this Letter, we consider a perforated microsphere with an air-filled single pinhole fabricated along the particle diameter and numerically analyze the peculiarities of WGM excitation in a nanostructured microsphere. A pinhole isolates the energy backflow region of a resonant mode and changes a perforated microsphere into an efficient optical tweezer. For the first time to our knowledge, we reveal the multiple enhancement of backflow intensity in the pinhole at a WGM resonance and discuss the way for its manipulation.
description: 4 pages, 3 figures
Varieties of capitalism in light of the euro crisis
Creators: name: Hall, Peter A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: This article examines the implications of the euro crisis for theories of political economy associated with ‘varieties of capitalism’, considering how those theories help explain the origins of the crisis and how developments during it mandate revisions in such theories. Efforts to understand the crisis have extended these theories in four directions. They have inspired an emerging literature on growth models that integrates the demand side of the economy into theories once oriented to its supply side. They have led to more intensive investigation of the political economies of East Central Europe and Southern Europe. The crisis has drawn attention to the international dimensions of varieties of capitalism and to problems of adjustment, injecting an element of dynamism into varieties of capitalism analyses and underlining that adjustment is a political as well as an economic problem.