cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ON DEMAND: Assessing Assessments: Delving into the Inaugural Pilot Review Process of Academic Annual Assessments
Creators: name: Serslev, Sheena
Publisher: name: Innovations in Teaching & Learning Conference Proceedings
Year: 2021

description: In an effort to model promising assessment practices and provide formative feedback to academic programs, the Office of Institutional Effectiveness and Planning (OIEP) in collaboration with the Mason Academic Assessment Council (MAAC) implemented a holistic review process of the academic program submission to Mason’s Annual Assessment. Each council member engaged in a small group and peer-driven process. Each group was assigned academic programs to review utilizing a co-developed rubric that included each component of a program’s submission to the Mason Annual Assessment: an organizational mission, curriculum map(s), student learning outcomes, measures, results, and improvements. Recognizing the disciplinary expertise of faculty, the reviews focused not on disciplinary content but on the assessment process itself and members engaged with the spirit of providing positive formative feedback. As a pilot and iterative process, we learned both about how best to engage in these discussions and about how we can evolve this process to support program improvement and student learning. OIEP hosted sessions in January to frame the feedback, clarify the role of the reviewer, and share themes from the feedback. Our video presentation will illustrate the connection between course level teaching and learning with annual program assessment. We will share findings from a meta-analysis of 200 academic program submissions at George Mason University and highlight institutional steps towards building a sustainable culture of assessment.
description: Innovations in Teaching & Learning Conference Proceedings, Vol. 13 (2021): Fostering Inclusive Excellence
Exploring the connection between emotional intelligence and first year experiences of undergraduate students at one Canadian university
Creators: name: James, Cindy Lou
Publisher: name: University of British Columbia
Year: 2014

description: There is a general consensus that the first year of university offers significant challenges, as new students not only adjust to the academic rigor of post-secondary schooling, but also to new social and cultural milieus. Thus, emotional intelligencethe ability to identify, process and manage emotions to affect positive behaviourmust play an important role during this transitional year, but how so? This mixed methods study was designed to answer that question by thoroughly investigating the connections between emotional intelligence (EI) and the first year experiences of students at a Canadian university. To do so, the EI of first year students, as measured by the BarOn Emotional Quotient Inventory (EQ-i), was assessed at the beginning of their studies and at the end of their first year during the 2010-2011 academic year at Thompson Rivers University. Quantitative and qualitative indicators of performance, engagement, experiences, and potential associations were examined, as were changes in EI and gender effects. The findings from this study suggest there is a complicated connection between emotional intelligence and first year experiences of students. Although students felt EI played an important role, the findings revealed no significant correlations between EI and academic achievement, and very few significant associations between EI and students’ nonacademic experiences in first year. However, there was a strong connection between first year experiences and changes in emotional intelligence, as most EI mean scores increased, many significantly, from the pre to the post assessment. Finally, the EI scores of male students differed from those of female students in some facets that appeared to influence engagement, but not academic performance.
ON DEMAND: Drawing on students’ work experience to facilitate in-class and out-of-class learning
Creators: name: Bellos, Ioannis
Publisher: name: Innovations in Teaching & Learning Conference Proceedings
Year: 2021

description: In graduate and professional courses, a significant part of student learning happens through in-class participation and out-of-class networking. In-class participation allows students to share their views on topics and case studies discussed in class by drawing from their own experiences. Similarly, out-of-class networking allows students to share their experiences and discover commonalities and professional opportunities in domains that previously appeared to be outside their comfort zone. The pandemic has affected significantly both learning mechanisms. To counteract this, last Fall I implemented two initiatives in my core MBA course (three sections; two delivered F2F and one via Zoom). Specifically, during each session, I asked students if they would like to volunteer to give a short, informal presentation on how the topic covered in class that day relates to their experience, to be presented in class the next week. There are two main benefits of these presentations: students get better acquainted with each other and they learn the practical applicability of the concepts from class, making the material more relatable and, thus, more memorable. Right after each class, I would also ask students to share their “Aha” moments on the discussion board in Blackboard, which I did not grade so they did not feel this is busy work but rather a means to express themselves. I will discuss how these two initiatives were received by the students as well as the main implementation challenges.
description: Innovations in Teaching & Learning Conference Proceedings, Vol. 13 (2021): Fostering Inclusive Excellence
Handicap e inclusione sociale. Un esame della normativa italiana
Creators: name: Torrioni, Paola Maria
name: Albano, Roberto
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2011
Subjects: SPS/07 Sociologia generale
SPS/08 Sociologia dei processi culturali e comunicativi

description: The ideal of individual self-realisation, which has become one of the fundamental values of Western societies, is likely to generate a non-inclusive vision of the social system, if not coupled with a strong idea of social integration. An inclusive welfare state protects against this risk of a social-darwinistic vision of the social system. The critical examination of the Italian Law 104/1992 (and subsequent modifications), often referred to as a good example of inclusive normative, shows a latent conception of the social system as an entity demanding a “functional” adaptation of individuals with disabilities: e.g. people with disabilities have to prove their capabilities or acquire skills to enter tasks in “normal” work situations. Instead, the authors contend that work situations, as well as other life-situations, are always adaptable to the needs of well-being of the individuals.
ON DEMAND: Using the Writing Center to Support Student Writing in Your Course
Creators: name: Lawrence, Susan
Publisher: name: Innovations in Teaching & Learning Conference Proceedings
Year: 2021

description: Have you wondered how the Writing Center can support student writing in your course? This short video provides concrete tips and strategies for drawing on Writing Center resources.
description: Innovations in Teaching & Learning Conference Proceedings, Vol. 13 (2021): Fostering Inclusive Excellence
A novel self-assembly based on double-layer zinc porphyrin sensitizers in supramolecular solar cell
Creators: name: Wu, Yu
name: Liu, Hua
name: Liu, Jia-Cheng
name: Li, Ren-Zhi
name: Jin, Neng-Zhi
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology

description: Two new self-assemblies based on zinc porphyrin dyes ZnPx-ZnPA (x = 1, 2) were synthesized and used for dye-sensitized solar cells. Capping layer dyes consist of zinc porphyrin (ZnP) as core unit and carbazole (P1), phenothiazine (P2) as electron-donating group. The dye ZnPA contains carboxylic group as an anchor porphyrin with upper dyes (denoted as ZnP1 and ZnP2) formed dyads by coordination bonds of Zn-to-ligand self-assembled devices. The assembly modes were also verified by transmission electron microscopy (TEM). The influence of the upper porphyrins on molecular structure as well as photovoltaic performance was investigated via photophysical and electrochemical studies and calculations. With addition of the phenothiazine unit, the ZnP2-ZnPA possesses better light-harvesting capability with a significantly red-shifted Q-band. The photoelectrochemical efficiencies for ZnP2-ZnPA are better than those of ZnP1-ZnPA ascribed to larger Jsc and Voc.
Temps, autonomie et discrétion : analyse d’activités dans la maintenance ferroviaire / Time, autonomy and discretion: activity analysis in railway maintenance /  Tempo, autonomia e discrezionalità: analisi di attività nella manutenzione ferroviaria
Creators: name: De La Garza, Cecilia
name: Maggi, Bruno
name: Weill-Fassina, Annie
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2011
Subjects: M-PSI/06 Psicologia del lavoro e delle organizzazioni
SECS-P/08 Economia e gestione delle imprese
SECS-P/10 Organizzazione aziendale

description: This paper shows a collaboration between the study of organizational action and ergonomic analysis. The regulation of the processes of work action and the cognitive regulation of operators are jointly studied in the comparison of two real-world case studies focused on the maintenance of railway infrastructure: the maintenance of the line and the repair of electrical signaling installations. The interactions between the affirmation of autonomy or the exercise of discretion and different approaches to the time management of working activities affect in various ways the reliability of the system. In urgent cases, the affirmation of autonomy may promote reliability, while in case of time pressure the exercise of discretion may increase the risk of unreliability.
ON DEMAND: Learning to Write Computer Programs is Like Learning to Play the Piano
Creators: name: Shuman, Gene
Publisher: name: Innovations in Teaching & Learning Conference Proceedings
Year: 2021

description: The artifact is a two minute video animation explaining how learning to write computer programs (software) is like learning to play the piano. Both require a significant amount of time, effort and concentration. Just as a jazz pianist learns to improvise on an underlying chord structure, programmers learn fundamental algorithms and write code that is a variation on those fundamentals. When a musician is performing a solo and the programmer is deep into creating the logic of a program, both enter a kind of mental "zone" which locks out distractions and suspends awareness of time. The purpose of the video is motivational. It attempts to explain the poorly understood process of creating computer code by providing an analogy to something that's more familiar to many. It also shows why the programming process requires a sizable time investment as well as concentration, and practice since all those are required to master a musical instrument like the piano. Providing such an analogy can help explain how a student might approach learning some new challenging skill and knowledge and justify the time required for a course. The video narrator is a cartoon avatar of the course professor, providing a light hearted and possibly silly, yet illuminating point about the programming process. The video is presented in selected sections of three GMU IST Department programming courses: IT-109, IT-209, and IT-309.
description: Innovations in Teaching & Learning Conference Proceedings, Vol. 13 (2021): Fostering Inclusive Excellence
Additional file 1 of Effects of pre-pregnancy body mass index and gestational weight gain on maternal and infant complications
Creators: name: Sun, Yin
name: Shen, Zhongzhou
name: Zhan, Yongle
name: Wang, Yawen
name: Ma, Shuai
name: Zhang, Suhan
name: Liu, Juntao
name: Wu, Sansan
name: Feng, Yahui
name: Chen, Yunli
name: Cai, Shuya
name: Shi, Yingjie
name: Ma, Liangkun
name: Jiang, Yu
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Mental Health

description: Additional file 1: Supplementary Table 1. Pre-pregnancy BMI categorization according to the WHO cut-points for Asian adults. Supplementary Table 2. Gestational weight gain (GWG) categorization according to the 2009 Institute of Medicine (IOM) recommendations.
Quasihyperbolic metric and Möbius transformations
Creators: name: Klén, Riku
name: Vuorinen, Matti
name: Zhang, Xiaohui
Publisher: name: arXiv
Year: 2011
Subjects: subject: Complex Variables (math.CV)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 30C60, 51M10

description: An improved version of quasiinvariance property of the quasihyperbolic metric under Möbius transformations of the unit ball in ${\mathbb R}^n, n \ge 2,$ is given. Next, a quasiinvariance property, sharp in a local sense, of the quasihyperbolic metric under quasiconformal mappings is proved. Finally, several inequalities between the quasihyperbolic metric and other commonly used metrics such as the hyperbolic metric of the unit ball and the chordal metric are established.
description: 14 pages
The organization of a unique event: the case of the Olympic Games of Torino 2006 / L’organizzazione di un evento unico: il caso dei Giochi Olimpici di Torino 2006
Creators: name: Barbini, Francesco Maria
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2011
Subjects: SECS-P/10 Organizzazione aziendale

description: This contribution describes the decisions and actions taken by the Torino Organizing Committee for the XX Olympic Winter Games. The events presented in the case are analyzed in the light of different theoretical perspectives in order to reflect on the planning process of a unique event, one that could not be postponed or delayed, such as the Olympic Games.
This work is aimed neither at identifying best practices leading to successful events, nor at implementing a checklist for future operators involved in the organization of next Olympic Games; instead, through developing different theoretical interpretations, this paper proposes an organizational discussion about relevant phenomena and fosters a reflection on wider issues related to organizational design and people management in unique events.
In silico drug designing for COVID-19: an approach of high-throughput virtual screening, molecular, and essential dynamics simulations
Creators: name: Kumar, Rakesh
name: Kumar, Rahul
name: Tanwar, Pranay
Publisher: name: Taylor & Francis
Year: 2021
Subjects: Biophysics
Biochemistry
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified

description: Severe acute respiratory syndrome-coronavirus2 (SARS-CoV2), a new coronavirus has emerged in Wuhan city of China, December 2019 causing pneumonia named Coronavirus disease-19 (COVID-19), which has spread to the entire world. By January 2021, number of confirmed cumulative cases crossed ∼104 million worldwide. Till date, no effective treatment or drug is available for this virus. Availability of X-ray structures of SARS-CoV2 main protease (Mpro) provides the potential opportunity for structure-based drug designing. Here, we have made an attempt to do computational drug design by targeting main protease of SARS-CoV2. High-throughput virtual screening of million molecules and natural compounds databases were performed followed by docking. After that, the protein-ligand complexes were optimized and rescoring of binding energies were accomplished through molecular dynamics simulation and Molecular mechanics Poisson Boltzmann surface area approaches, respectively. In addition, conformational effect of various ligands on protein was also examined through essential dynamics simulation. Three compounds namely ZINC14732869, ZINC19774413, and ZINC19774479 were finally filtered that displayed better binding affinities than N3 (known) inhibitor and formed conformationally stable complexes. Hence, the current study features the potential novel inhibitors against main protease of SARS-CoV2 which might provide an effective therapeutic strategy against COVID-19. Communicated by Ramaswamy H. Sarma
State-of-the-Art of Hand Exoskeleton Systems
Creators: name: Mozaffari Foumashi, Mohammad
name: Troncossi, Marco
name: Parenti Castelli, Vincenzo
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2011
Subjects: ING-IND/13 Meccanica applicata alle macchine

description: This paper deals with the analysis of the state-of-the-art of robotic hand exoskeletons (updated at May 2011), which is intended as the first step of a designing activity. A large number of hand exoskeletons (both products and prototypes) that feature some common characteristics and many special peculiarities are reported in the literature. Indeed, in spite of very similar functionalities, different hand exoskeletons can be extremely different for the characteristics of their mechanism architectures, control systems and working principles. The aim of this paper is to provide the reader with a complete and schematic picture of the state-of-the-art of hand exoskeletons. The focus is placed on the description of the main aspects that are involved in the exoskeleton design such as the system kinematics, the actuator systems, the transmission parts and the control schemes. Additionally, the critical issues provided by the literature analysis are discussed in order to enlighten the differences and the common features of different practical solutions. This paper may help to understand both the reasons why certain solutions are proposed for the different applications and the advantages and drawbacks of the different designs proposed in the literature. The motivation of this study is the need to design a new hand exoskeleton for rehabilitation purposes.
Multi-scale approximation of the matching distance for shape retrieval
Creators: name: Cerri, Andrea
name: Di Fabio, Barbara
name: Medri, Filippo
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2011
Subjects: INF/01 Informatica
MAT/03 Geometria

description: Abstract. This paper deals with the concepts of persistence diagrams and matching distance. They are two of the main ingredients of Topological Persistence, which has proven to be a promising framework for shape comparison. Persistence diagrams are descriptors providing a signature of the shapes under study, while the matching distance is a metric to compare them. One drawback in the application of these tools is the computational costs for the evaluation of the matching distance. The aim of the present paper is to introduce a new framework for the approximation of the matching distance, which does not affect the reliability of the entire approach in comparing shapes, and extremely reduces computational costs. This is shown through experiments on 3D-models.
Der gefälschte Kalif - eine Einführung in die Sīrat al-Ḥākim bi-Amrillāh
Creators: name: Lenora, Antje
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2011
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 890
subject: 297
subject: 490

description: Das hier besprochene und inhaltlich zusammengefasste arabische Epos Sīrat al-Ḥākim bi-Amrillāh, dessen Entstehungszeit in die der späteren, städtischen siyar šaʽbīya fällt, reflektiert die Geschichte der Fatimidenkalifen, besonders die Vita des Herrschers al-Ḥākim bi-Amrillāh (reg. 969-1021) und seines Sohnes aẓ-Ẓāhir (reg. 1021-1036). Es ist in Handschriften überliefert, deren Datierungen vom 15. bis ins 19. Jh. reichen. Die epische, siyar-typische Ausarbeitung des historischen Stoffes lässt sich anhand von Sprache, narrativer Struktur, Länge des Stoffes, Thematik und selbstreferentieller Betrachtung feststellen. Das Werk lässt eine starke Bezugnahme der Verfasser auf historiographische, sunnitische Quellen aus der späten Aiyubiden- und Mamlukenzeit erkennen. Im Vergleich zeigt sich, dass diese genutzt wurden, um die fatimidische Geschichte umzudeuten und in den Kontext der kathartischen Erzählung vom Siegeszug eines triumphalen, orthodoxen Islams einzubetten. Ebenso lässt sich nachweisen, dass die Verfasser der Sīra ein recht breit angelegtes Fachwissen reproduzieren konnten und gelehrte Quellen kannten. Die abstrakte Darstellung der Handlung als eine Heldenreise ermöglicht den Vergleich mit anderen Vertretern des Genres und zeigt den markanten Unterschied in der Struktur, welcher durch die Figur des dichotomen, tragischen Helden al-Ḥākim zustande kommt, und wie das Dilemma aufgelöst wird.
description: The dissertation addresses the rather unknown Arabian popular epic Sīrat al-Ḥākim bi-Amrillāh which is an urban representative of the later siyar shaʿbiyya and reflects the history of the Fatimid caliphs al-Ḥākim bi-Amrillāh (r. 969-1021) and his successors. The textual witnesses cover manuscripts from 15th to 19th century. The epic, siyar-specific composition of the historical material is characterized by language, narrative structure, extension, themes and motifs and self- reflection of the texts. The Sīra shows a strong reference to Sunni historiographical sources from the late Ayyubid and Mamluk period. Comparing these sources with the Sīra, it becomes visible that the narrators of the Sīra used their knowledge of the historiographical material to re-interpret Egyptian Fatimid history and to incorporate it into the context of a cathartic narration of the triumph of Sunni orthodox Islam. An abstract presentation of the epic as a hero’s journey, allows the comparison with other representatives of the siyar shaʿbiyya and shows the difference in the structure of the narration, due to the character of the dichotomic and tragical hero al-Ḥākim, and how the dilemma is being solved.
ON DEMAND: Experiential Learning Project: Applying classroom knowledge to real life situations to meet learning outcomes.
Creators: name: Stroiney, Debra
Publisher: name: Innovations in Teaching & Learning Conference Proceedings
Year: 2021

description: The experiential learning/client project implemented in KINE 350 is a semester long project that emphasizes knowledge in the course as well as pre-requisite classes. The project requires students to take an assigned client through a consultation, exercise assessment, and to write an exercise prescription to improve health and fitness. The student then meets with the client to teach them the exercises and gain feedback on the prescription they created. Check-ins and feedback on the project are given throughout the semester to keep the student on track. Volunteer clients are recruited from lower level Kinesiology courses (ex: KINE 100) to purposely expose these students to what is to come, and hopefully get them excited about progressing through their classes. This project also acts as a mini capstone addressing both analytical and experiential learning outcomes. This course falls about half way through the program and is taken the semester prior to going on their first internship. This project allows students to practice what they have learned at this point in the program with a “real” person in preparation for working with the public at their internship sites. Sharing my experiences with this project will allow instructors across disciplines to learn about creating a semester long project specifically incorporating experiential learning in their classroom. It allows instructors to gain information on creation an experiential project for their area even if the student may not have the experience or credentials needed if on a job or internship site. This type of assignment also allows for the measurement of program outcomes which can be reported in connection with program goals. Learning to give appropriate feedback on this type of project is key to the students’ success. This assignment was adapted to an online format when we pivoted last year. Revisions were made to the project to ensure both the students and program were meeting the outcomes for experiential learning. Adaptations to experiential projects such as this for an online class will also be discussed.
description: Innovations in Teaching & Learning Conference Proceedings, Vol. 13 (2021): Fostering Inclusive Excellence
The role of podocalyxin in breast cancer progression and metastasis
Creators: name: Snyder, Kimberly Ashley
Publisher: name: University of British Columbia
Year: 2015

description: The molecular heterogeneity of breast cancers makes them very challenging to diagnose and treat. While many breast tumors are curable surgically, others have an increased tendency to relapse or metastasize. Podocalyxin (gene name PODXL) is a CD34-related sialomucin that is important in regulating cell adhesion, migration, and polarity of hematopoietic progenitors and vascular endothelia. Previously, podocalyxin expression in primary breast tumor cells has been correlatively linked to poor patient survival. In addition, overexpression of podocalyxin in MCF-7 luminal breast cancer cells results in an overall increase in aggressive morphological features including: apical bulging, microvillus formation, and disrupted integrin targeting to the basolateral surface. To determine whether podocalyxin has a definitive role in breast tumor progression, I used shRNA-based vectors to silence expression of PODXL in a basal-like breast cancer cell-line, MDA.MB-231, which normally expresses high levels of endogenous podocalyxin, forms poorly polarized monolayers and tumorspheres in vitro and rapidly forms metastatic tumors in vivo. I found that podocalyxin impairs adhesion to extracellular matrices (ECM) and is critical for the formation of tumorspheres in vitro. In addition, I found that podocalyxin expression is critical for both primary tumor development and the formation of distant metastases in the lung, liver, and bone marrow in xenografted mice. These findings were corroborated by use of a mouse mammary tumor cell line (4T1) in a syngeneic model of metastatic tumor progression. Furthermore, in collaboration with the Centre for Drug Research and Development (UBC), I evaluated the ability of candidate therapeutic antibodies to podocalyxin to block the growth and metastasis of established tumors. One candidate antibody, known as anti-PODO, was found to significantly inhibit primary tumorigenesis in a pre-clinical mouse model. In summary, in this thesis I demonstrate for the first time that podocalyxin plays a causal role in promoting the growth of solid tumors and enhancing metastasis of tumor cells to distant organs. These findings have the potential to improve treatments for breast cancer patients by providing a highly specific and well-tolerated adjuvant therapy for metastatic disease.
Lattice QCD calculation of $ππ$ scattering length
Creators: name: Fu, Ziwen
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We study s-wave pion-pion ($ππ$) scattering length in lattice QCD for pion masses ranging from 330 MeV to 466 MeV. In the "Asqtad" improved staggered fermion formulation, we calculate the $ππ$ four-point functions for isospin I=0 and 2 channels, and use chiral perturbation theory at next-to-leading order to extrapolate our simulation results. Extrapolating to the physical pion mass gives the scattering lengths as $m_πa_0^{I=2} = -0.0416(2)$ and $m_πa_0^{I=0} = 0.186(2)$ for isospin I=2 and 0 channels, respectively. Our lattice simulation for $ππ$ scattering length in the I=0 channel is an exploratory study, where we include the disconnected contribution, and our preliminary result is near to its experimental value. These simulations are performed with MILC 2+1 flavor gauge configurations at lattice spacing $a \approx 0.15$ fm.
description: Remove some typos
5-GHz VCO with a wide tuning range using an InPbased
RTD/HBT technology
Creators: name: Choi, Sunkyu
name: Kim, Taeho
name: Lee, Bangkeun
name: Yang, Kyounghoon
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2004
Subjects: ING-INF/01 Elettronica

description: This paper presents a fully integrated 5 GHz
voltage-controlled oscillator (VCO) with a wide frequency
tuning range based on an InP-based RTD/HBT technology.
In order to increase the frequency tuning range of the VCO,
the base-to-collector p-n junction of HBT is exploited as a
varactor of an LC resonator. The VCO generates a
maximum output power of -19.5 dBm which is operated at a
bias current of 9.5 mA and a supply voltage of 0.8 V with a
corresponding DC power consumption of about 7.6 mW.
The fabricated RTD/HBT VCO shows a wide frequency
tuning range of 710 MHz. In addition, a low phase noise of -
115 dBc/Hz at 1 MHz offset was obtained.
Isolierung pathogen-induzierter MAP Kinase-Signalkomplexe aus Arabidopsis thaliana
Creators: name: Spielau, Claudia
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2010
Subjects: subject: MAP-Kinase
subject: Ackerschmalwand
subject: Pathogenese
subject: Online-Publikation
subject: Hochschulschrift
subject: 571.742364
subject: 570

description: Mitogenaktivierte Protein-Kinasen (MAPK) spielen in der Signaltransduktion und der Zellantwort auf externe Stimuli eine zentrale Rolle (Ichimura et al. 2000, Zhang et al. 2006, Tena et al. 2001). Sie sind in Netzwerken organisiert, wobei einzelne Signalkomponenten auch in verschiedenen Kaskaden eingesetzt werden können. Die Spezifität kann über die Kompartimentierung der Komponenten oder über Adapter- und Gerüstproteine erfolgen (Burack und Shaw 2000, Schwartz und Madhani 2006, Tsunoda et al. 1998). In dieser Arbeit wurden solche Kinase-Interaktionen mittels Massenspektrometrie und Tandem-Affinitätschromatographie (TAP, Rigaut et al. 1999) bzw. StrepII-Affinitätschromatographie (Witte et al. 2004) in Arabidopsis thaliana untersucht. Hauptaugenmerk lag dabei auf der Anreicherung von Proteinkomplexen der in die Pathogen-Abwehr involvierten MAP Kinasen. Hinweise auf prä-formierte MAPK Komplexe in Arabidopsis thaliana konnten bereits mittels Gelpermeations-Chromatographie für die Wildtyp und die TAP-markierten MPK3 und MPK6 erhalten werden. Die Fusionsproteine MPK3-TAP, MPK6-TAP und MPK6-strepII waren vollständig funktional. Nach flg22-Elizitierung lagen die markierten MPK3 und MPK6 phosphoryliert vor und konnten ein artifizielles Substrat in einem Aktivitäts-Assay umsetzen. Diese Daten wiesen auf eine erfolgreiche Integration der markierten MAPK in ihre physiologisch relevanten Signalkaskaden hin. Die Affinitätschromatographie erfolgte jeweils mit Blattmaterial von stabilen Pflanzen-Transformanten, da keine einsetzbaren Zellkultur-Transformanten generiert werden konnten. RuBisCO und andere abundante Kontaminanten konnten durch eine Vorfraktionierung erfolgreich abgereichert werden. Die ko-eluierten Proteine wurden anschließend in einer GeLCoder einer Shotgun-Analyse mittels 1D-nano-LC-ESI-IT-MS/MS untersucht. Neben den markierten MAPK selbst konnten weitere ko-eluierte Proteine in den Eluaten aus beiden Affinitätschromatographie-Ansätzen identifiziert werden. Dabei traten bei der StrepIIProteinreinigung mehr falsch-positive Identifizierungen auf, da weder die Einschritt-Strategie noch die damit kombinierte PEG-Vorfraktionierung ausreichend zur Abreicherung der Kontaminanten und der Anreicherung von MAPK Proteinkomplexen war. Die Ammoniumsulfat-Vorfraktionierung und Tandem-Affinitätschromatographie führte dagegen zu einer ausreichenden Anreicherung von Proteinkomplexen. Damit konnten erfolgreich einige interessante koeluierte Proteine identifiziert werden, von denen PBS1 (avrPphB suceptible1) in einer anschließenden BiFC-Analyse erste Hinweise auf eine schwache in vivo Interaktion mit der MPK3 lieferte.
SHOWCASE: Strategies for Non-Exam Assessments, Grading, and Providing Feedback (90 mins)
Creators: name: Ross, Cathy
name: Figueroa, Lydia
name: Leslie, Timothy
name: Maulden, Patricia
name: Stroiney, Debra
name: Winter, Patrice
name: Zhou, Steven
Publisher: name: Innovations in Teaching & Learning Conference Proceedings
Year: 2021

description: Assessment is an important part of the learning process. Grading and giving feedback can be time intensive activities, which have historically resulted in the overuse or misuse of multiple-choice style exams. The goals of this session are to present, discuss, and model the essential components of non-exam assessments, grading and feedback. Part 1-Participant Prior Knowledge The first part of the session will begin by asking participants why they think non-exam assessments and feedback are important in teaching. Then they will be asked to write on a whiteboard examples of non-exam assessments and feedback they have given in the past and what makes these assessments and feedback effective. Part 2-Case Studies and Small Group Discussion The goal of the second part of the session is to give participants the opportunity to put these ideas into practice. They will do this by examining some samples of course material that presenters have taught and coming up with appropriate ways to assess students’ understanding of the material. Participants will examine samples of assignments with or without rubrics and discuss the most effective and fairest ways to grade such assignments. Participants will also examine samples of students’ assignments and practice giving feedback on these assignments. The second part of the session will be conducted mainly in breakout groups of 4-5 participants led by one of the speakers who will record key take-aways on a shared document for their group. Part 3-Whole Group Discussion We will wrap up by asking speakers to share highlights from the small group discussions and ask participants to share any additional key take-aways that they learned about strategies for non-assessment exams, grading and feedback via a virtual whiteboard or in the chat. Conveners: Cathy Ross, Laura Todd Panelist Speakers: Melissa Brockelman-Post (College of Humanities and Social Sciences) Lydia Figueroa (Norfolk State University and Mason Partner) Timothy Leslie (College of Science) Patricia Maulden (Carter School of Peace and Conflict Resolution) Debra Stroiney (College of Education and Human Development) Patrice Winter (College of Health and Human Services) Steven Zhou (College of Humanities and Social Sciences)
description: Innovations in Teaching & Learning Conference Proceedings, Vol. 13 (2021): Fostering Inclusive Excellence
Single-molecule pulling: phenomenology and interpretation
Creators: name: Franco, Ignacio
name: Ratner, Mark A.
name: Schatz, George C.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Single-molecule pulling techniques have emerged as versatile tools for probing the noncovalent forces holding together the secondary and tertiary structure of macromolecules. They also constitute a way to study at the single-molecule level processes that are familiar from our macroscopic thermodynamic experience. In this Chapter, we summarize the essential phenomenology that is typically observed during single-molecule pulling, provide a general statistical mechanical framework for the interpretation of the equilibrium force spectroscopy and illustrate how to simulate single-molecule pulling experiments using molecular dynamics.
description: arXiv admin note: text overlap with arXiv:0908.2208
Die Rolle der vakuolären NHX-Transporter bei der Auslösung der Biosynthese von Benzophenanthridin-Alkaloiden in Eschscholzia californica
Creators: name: Weigl, Sophie
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2015
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 571

description: Zellen von Eschscholzia californica reagieren auf Elicitor-Kontakt mit der Bildung von Benzophenanthridin-Alkaloiden. Der Signalweg der zur Expression von Biosynthese-Enzymen führt, beruht auf der Aktivierung einer Phospholipase A2 wodurch Lysophophatidylcholin (LPC) gebildet wird, welches als second messanger einen vakuolären H+-Efflux auslöst, der zur transienten Ansäuerung des Cytoplasmas führt. Die vorliegenden Ergebnisse demonstrieren, dass nur einer von vier in Eschscholzia identifizierten vakuolären Na+/H+-Transportern (NHX) diesen H+-Efflux vermittelt. RNAi-basiertes silencing der Isoformen EcNHX1, 3 und 4 resultiert in stabilen Zelllinien mit eingeschränkter Kapazität des Na+-abhängigen vakuolären H+-Efflux und der elicitor-ausgelösten Alkaloid-Überproduktion. Alle vier Isoformen komplementieren den Kapazitätsverlust einer Δnhx-Nullmutante von Saccharomyces bezüglich des Na+-abhängigen vakuolären H+-Efflux, aber nur der heterolog expremierte EcNHX1-Transporter ist durch LPC stimulierbar. Ein 3D Homologie-Modell bestätigt, dass nur die EcNHX1-Proteinsequenz eine potentielle LPC-Bindestelle aufweist.
description: Cell cultures of Eschscholzia californica react to a fungal elicitor by the overproduction of antimicrobial benzophenanthridine alkaloids. The signal chain towards the expression of biosynthetic enzymes includes a cytoplasmatic peak of lysophosphatidylcholine (LPC) by activation of phospholipase A2, followed by a transient vacuolar H+ efflux, resulting in a shift of cytosolic pH. The present study demonstrates that one of four vacuolar Na+/H+ antiporters (NHX) identified in Eschscholzia mediates this H+ flux. Simultaneous, RNAi-based silencing of EcNHX1, 3 and 4 resulted in stable cell strains with diminished capacities of Na+ dependent vacuolar H+ efflux and elicitor-triggered overproduction of alkaloids. Each of the EcNHX genes of Eschscholzia reconstituted the lack of Na+ dependent H+ efflux in a Δnhx null mutant of Saccharomyces, but only the yeast strain expressing EcNHX1 was stimulated by LPC. 3D homology models indicate that only EcNHX1 offers a plausible binding pocket for LPC and support the essential role of EcNHX1 in signal transfer between elicitor contact and gene activation by recruiting vacuolar H+ for the signaling process.
A Distributed Model of Four-Port Monolithic
Transformer
Creators: name: Lee, Dong Ho
name: Ko, Sangsoo
name: Jeon, Sang-Hoon
name: Park, Jae-Woo
name: Hong, Songcheol
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2004
Subjects: ING-INF/01 Elettronica

description: This paper deals with modeling of a monolithic spiral transformer. The transformer is designed and fabricated as a symmetrical octagonal spiral structure using two-metal layer process on GaAs substrate for input balun applications of 2 GHz and 5 GHz push-pull power amplifiers. A distributed model of the transformer is developed to fit in wide frequency range with four ports.
The model includes the skin effect which describes increase
in series resistance with frequency. Six different sets of twoport s-parameters are measured to obtain full
characteristics of the four-port transformer while the other
two ports are shorted to ground. The model is validated
with measurement results in 100 MHz to 6 GHz.
Point source identification in non-linear advection-diffusion-reaction systems
Creators: name: Mamonov, Alexander V.
name: Tsai, Yen-Hsi Richard
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mathematical Physics (math-ph)
subject: Numerical Analysis (math.NA)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 65M32

description: We consider a problem of identification of point sources in time dependent advection-diffusion systems with a non-linear reaction term. The linear counterpart of the problem in question can be reduced to solving a system of non-linear algebraic equations via the use of adjoint equations. We extend this approach by constructing an algorithm that solves the problem iteratively to account for the non-linearity of the reaction term. We study the question of improving the quality of source identification by adding more measurements adaptively using the solution obtained previously with a smaller number of measurements.
description: 27 pages, 10 figures, 3 tables
On the non-local heat kernel expansion
Creators: name: Codello, A.
name: Zanusso, O.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We propose a novel derivation of the non-local heat kernel expansion, first studied by Barvinsky, Vilkovisky and Avramidi, based on simple diagrammatic equations satisfied by the heat kernel. For Laplace-type differential operators we obtain the explicit form of the non-local heat kernel form factors to second order in the curvature. Our method can be generalized easily to the derivation of the non-local heat kernel expansion of a wide class of differential operators.
description: 23 pages, 1 figure, 31 diagrams; references added; to appear in JMP
Subharmonically Pumped Image Rejection Mixer
for K-band Applications
Creators: name: Lee, Moon-Que
name: Moon, Seong-Mo
name: Ryu, Keun-Kwan
name: Jang, Dong-Phil
name: Yom, In-Bok
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2004
Subjects: ING-INF/01 Elettronica

description: A balanced single side-band (SSB) mixer
employing a sub-harmonic configuration is designed for up
and down conversions in K-band. The designed mixer uses
anti-parallel diode (APD) pairs to effectively eliminate even
harmonics of local oscillator (LO) spurious signal. For the
more, to reduce the odd harmonics of LO at RF port, we
employ a balanced configuration for LO. The fabricated chip
shows 12 ±2dB of conversion loss and image-rejection ratio of
about 20dB for down conversion at RF frequencies of 24-
27.5GHz. As an up-conversion mode, the designed chip shows
12dB of conversion loss and image-rejection ratio of 20 ~ 25
dB at RF frequencies of 25 to 27GHz. The odd harmonics of
LO are measured below -37dBc.
Supplemental Figures from Bayesian tip dating reveals heterogeneous morphological clocks in Mesozoic birds
Creators: name: Zhang, Chi
name: Wang, Min
Publisher: name: The Royal Society
Year: 2019

description: Recently, comprehensive morphological datasets including nearly all the well-recognized Mesozoic birds became available, making it feasible for statistically rigorous methods to unveil finer evolutionary patterns during early avian evolution. Here, we exploited the advantage of Bayesian tip dating under relaxed morphological clocks to estimate both the divergence times and evolutionary rates while accounting for their uncertainties. We further subdivided the characters into six body regions (i.e. skull, axial skeleton, pectoral girdle and sternum, forelimb, pelvic girdle and hindlimb) to assess evolutionary rate heterogeneity both along the lineages and across partitions. We observed extremely high rates of morphological character changes during early avian evolution, and the clock rates are quite heterogeneous among the six regions. The branch subtending Pygostylia shows an extremely high rate in the axial skeleton, while the branches subtending Ornithothoraces and Enantiornithes show notably high rates in the pectoral girdle and sternum and moderately high rates in the forelimb. The extensive modifications in these body regions largely correspond to refinement of the flight capability. This study reveals the power and flexibility of Bayesian tip dating implemented in MrBayes to investigate evolutionary dynamics in deep time.
Character Description from Bayesian tip dating reveals heterogeneous morphological clocks in Mesozoic birds
Creators: name: Zhang, Chi
name: Wang, Min
Publisher: name: The Royal Society
Year: 2019

description: Recently, comprehensive morphological datasets including nearly all the well-recognized Mesozoic birds became available, making it feasible for statistically rigorous methods to unveil finer evolutionary patterns during early avian evolution. Here, we exploited the advantage of Bayesian tip dating under relaxed morphological clocks to estimate both the divergence times and evolutionary rates while accounting for their uncertainties. We further subdivided the characters into six body regions (i.e. skull, axial skeleton, pectoral girdle and sternum, forelimb, pelvic girdle and hindlimb) to assess evolutionary rate heterogeneity both along the lineages and across partitions. We observed extremely high rates of morphological character changes during early avian evolution, and the clock rates are quite heterogeneous among the six regions. The branch subtending Pygostylia shows an extremely high rate in the axial skeleton, while the branches subtending Ornithothoraces and Enantiornithes show notably high rates in the pectoral girdle and sternum and moderately high rates in the forelimb. The extensive modifications in these body regions largely correspond to refinement of the flight capability. This study reveals the power and flexibility of Bayesian tip dating implemented in MrBayes to investigate evolutionary dynamics in deep time.
LC-Oscillator for 94 GHz Automotive Radar System
Fabricated in SiGe:C BiCMOS Technology
Creators: name: Winkler, Wolfgang
name: Borngräber, Johannes
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2004
Subjects: ING-INF/01 Elettronica

description: This paper presents the design and measurement of a voltage-controlled oscillator (VCO) for the use in a 94 GHz automotive radar system and other applications.
The oscillator has been fabricated in a 200
GHz SiGe:C BiCMOS technology with 0.25 µm minimum
feature size. The oscillator is fully integrated on a single
chip with a chip area of only 0.25 mm2.
The fabricated oscillator has a tuning range of 2.2 GHz
and a supply voltage of -3 Volt.
Can Inflation be Connected to Low Energy Particle Physics?
Creators: name: Hertzberg, Mark P.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: It is an interesting question whether low energy degrees of freedom may be responsible for early universe inflation. To examine this, here we present a simple version of Higgs-inflation with minimal coupling to gravity and a quadratic inflationary potential. This quantitatively differs from the popular non-minimally coupled models, although it is qualitatively similar. In all such models, new heavy fields must enter in order for the theory to be well behaved in the UV. We show that in all cases the Higgs self coupling lambda must be quite small in order to integrate out the heavy fields and use the resulting low energy effective field theory of the Higgs to describe inflation. For moderately sized lambda, the UV completion is required and will, in general, determine the inflationary regime. We discuss the important issue of the arbitrariness of the Lagrangians used in all these setups by presenting a new class of such models, including a supergravity version. This suggests that the inflationary potential is disconnected from low energy physics.
description: 6 pages, 1 figure, v2 updated with clarifications and more references