cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The immunoregulatory mechanisms of carcinoma for its survival and development
Creators: name: Du, Caigan
name: Wang, Yuzhuo, Ph.D.
Publisher: name: BioMed Central
Year: 2015

description: The immune system in patients detects and eliminates tumor cells, but tumors still progress persistently. The mechanisms by which tumor cells survive under the pressure of immune surveillance are not fully understood. This review is to present the evidence from clinical studies, showing a significant correlation of clinicopathological features of carcinoma with: (1) the loss of classical human leukocyte antigen class I, (2) the up-regulation of non-classical human leukocyte antigen class I, pro-apoptotic Fas ligand and receptor-binding cancer antigen expressed on SiSo cells I, and (3) the formation of immunosuppressive microenvironment by up-regulation of transforming growth factor-beta, Galectin-1, inhibitory ligand B7s, indoleamine 2,3-dioxygenase and arginase, as well as by recruitment of tumor-induced myeloid-derived suppressor cells and regulatory T cells. All of these factors may together protect carcinoma cells from the immune-cytotoxicity.
Chasing the dragon - characterizing cases of leukoencephalopathy associated with heroin inhalation in British Columbia
Creators: name: Buxton, Jane A.
name: Sebastian, Renee
name: Clearsky, Lorne
name: Angus, Natalie
name: Shah, Lena
name: Lem, Marcus
name: Spacey, Sian D.
Publisher: name: BioMed Central
Year: 2016

description: An association between leukoencephalopathy, a disease of the white matter of the brain, and smoking heroin is well recognized. This paper describes 27 cases of leukoencephalopathy identified in two cities in British Columbia, Canada 2001-2006; the largest number of geographically and temporally defined reported cases in North America. Twenty cases of leukoencephalopathy were identified in and around Vancouver with onset dates December 2001 to July 2003; seven further cases were identified in Victoria September 2005-August 2006. Twenty (74%) of all cases were male, two couples were reported and eleven cases (55%) had Asian ethnicity. One case reported smoking heroin on a single occasion and developed mild symptoms; all other cases were hospitalized. Thirteen (48%) cases died; all had smoked heroin for a minimum of 3 years. Testing of one available heroin sample identified no substance other than common cutting agents. Although a specific etiology was not identified our study supports the theory of an intermittent exposure to a toxic agent added to the heroin or a combustion by-product. It also suggests a dose response effect rather than genetic predisposition. Collaboration with public health, health professionals, law enforcement and persons who use illegal drugs, will facilitate the early identification of cases to enable timely and complete follow-up including obtaining samples. Testing of implicated heroin samples may allow identification of the contaminant and therefore prevent further cases. It is therefore important to ensure key stakeholders are aware of our findings.
Delivering high-resolution landmarks using inkjet micropatterning for spatial monitoring of leaf expansion
Creators: name: Wang, Lisheng
name: Beyer, Simon T.
name: Cronk, Quentin C. B.
name: Walus, Konrad
Publisher: name: BioMed Central
Year: 2015

description: Background: Inkjet micropatterning is a versatile deposition technique with broad applications in numerous fields. However, its application in plant science is largely unexplored. Leaf expansion is one of the most important parameters in the field of plant science and many methods have been developed to examine differential expansion rates of different parts of the leaf lamina. Among them, methods based on the tracking of natural landmarks through digital imaging require a complicated setup in which the leaf must remain fixed and under tension. Furthermore, the resolution is limited to that of the natural landmarks, which are often difficult to find, particularly in young leaves. To study the fine scale expansion dynamics of the leaf lamina using artificial landmarks it is necessary to place small, noninvasive marks on a leaf surface and then recover the location of those marks after a period of time. Results To monitor leaf expansion in two dimensions, at very fine scales, we used a custom designed inkjet micropatterning system to print a grid composed of c. 0.19 mm2 cells on small developing leaves of ivy (Hedera helix) using 40 μm dots at a spacing of c. 91 μm. The leaves in different growing stages were imaged under magnification to extract the coordinates of the marks which were then used in subsequent computer-assisted leaf expansion analyses. As an example we obtained quantified global and local expansion information and created expansion maps over the entire leaf surface. The results reveal a striking pattern of fine-scale expansion differences over short periods of time. In these experiments, the base of the leaf is a "cold spot" for expansion, while the leaf sinuses are "hot spots" for expansion. We have also measured a strong shading effect on leaf expansion. We discuss the features required to build an inkjet printing apparatus optimized for use in plant science, which will further maximize the range of tissues that can be printed at these scales. Conclusions To apply inkjet micropatterning to plant studies, we have successfully delivered landmarks on ivy leaf surfaces and achieved high-resolution, two-dimensional monitoring of leaf expansion at different growing stages. The measurement is capable of reliably identifying the fine scale changes during plant growth. As well as delivering landmarks, this technology may be used to deliver microscale targeted biological components such as growth hormones, and possibly be used to pattern sensors directly on the leaves.
Second harmonic generation analysis of early Achilles tendinosis in response to in vivo mechanical loading
Creators: name: Abraham, Thomas
name: Fong, Gloria
name: Scott, Alexander
Publisher: name: BioMed Central
Year: 2016

description: Background: Tenocytes have been implicated in the development of tendinosis, a chronic condition commonly seen in musculoskeletal overuse syndromes. However, the relation between abnormal tenocyte morphology and early changes in the fibrillar collagen matrix has not been closely examined in vivo. Second harmonic generation (SHG) microscopy is a recently developed technique which allows examination of fibrillar collagen structures with a high degree of specificity and resolution. The goal of this study was to examine the potential utility of SHG and multiphoton excitation fluorescence (MPEF) microscopy in understanding the relation between tenocytes and their surrounding collagenous matrix in early tendon overuse lesions. Methods: Histological preparations of tendon were prepared from adult male Sprague-Dawley rats subjected to an Achilles tendon loading protocol for 12 weeks (Rat-A-PED), or from sedentary age-matched cage controls. Second harmonic generation and multiphoton excitation fluorescence were performed simultaneously on these tissue sections in at least three different areas. Results: SHG microscopy revealed an association between abnormal tenocyte morphology and morphological changes in the fibrillar collagen matrix of mechanically loaded Achilles tendons. Collagen density and organization was significantly reduced in focal micro-regions of mechanically loaded tendons. These pathological changes occurred specifically in association with altered tenocyte morphology. Normal tendons displayed a regular distribution of fibre bundles, and the average size of these bundles as determined by Gaussian analysis was 0.47 μm ± 0.02. In comparison, fibre bundle measures from tendon regions in the vicinity of abnormal tenocytes could not be quantified due to a reduction in their regularity of distribution and orientation. Conclusions: SHG microscopy allowed high resolution detection of focal tendon abnormalities affecting the fibrillar collagen matrix. With ongoing repetitive loading, these tenocyte-associated focal collagen defects could predispose to the progression of overuse pathology.
Additional file 1 of Reducing cardiometabolic risk in adults with a low socioeconomic position: protocol of the Supreme Nudge parallel cluster-randomised controlled supermarket trial
Creators: name: Stuber, Josine M.
name: Joreintje D. Mackenbach
name: Boer, Femke E. De
name: Gert-Jan De Bruijn
name: Gillebaart, Marleen
name: Harbers, Marjolein C.
name: Hoenink, Jody C.
name: Klein, Michel C. A.
name: Middel, Cédric N. H.
name: Schouw, Yvonne T. Van Der
name: Schuitmaker-Warnaar, Tjerk Jan
name: Velema, Elizabeth
name: Vos, Anne L.
name: Waterlander, Wilma E.
name: Lakerveld, Jeroen
name: Beulens, Joline W. J.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 1 Tables with information on the food products to (not) be targeted in the supermarket (Table S1), on the types of healthy food nudges and examples of in-store use (Table S2), and the implementation fidelity checklist (Table S3).
A síkvidéki települések belvízzel és aszállyal szembeni rugalmas ellenálló képességének növelése
Creators: name: Priváczki-Juhászné Hajdu, Zsuzsanna
name: Muhoray, Árpád
Publisher: name: Magyar Hadtudományi Társaság
Year: 2020
Subjects: subject: inland water
subject: drought hazard
subject: urban flood risks
subject: resilience
subject: belvíz
subject: aszály
subject: települések vízkár veszélyeztetettsége
subject: reziliencia

description: Hadtudomány, vol. 30. Electronic issue., ISSN 1215-4121, eISSN 1588-0605
description: Hungary's exposure to water damage (flood and inland excess water flood) is significant, which is indicated by the classification of municipalities into disaster management classes. Improving resilience of settlements in plain areas is important for their flood-risk prevention activities. However, these towns are affected not only by water surplus situations, but droughts cause serious damage in these settlements. According to the climate change forecasts in Hungary, water management extremes, including inland excess water floods and drought damage, are expected to increase. In order to improve the resilience of the municipalities, technical measures are introduced in the paper, which may reduce the risk of inland excess water floods and the damage caused by droughts in urban areas. These measures should be determined on the basis of the local conditions
description: Magyarország ár- és belvízi veszélyeztetettsége jelentős, amely a települések katasztrófavédelmi osztályba sorolása kapcsán is megmutatkozik. A síkvidéki települések vízkárokkal szembeni rugalmas ellenálló képességének javítása a települések helyi vízkárelhárítási tevékenysége szempontjából fontos. Hazánk síkvidéki településeit azonban a víztöbbletek mellett a vízhiányos vízgazdálkodási helyzetek, az aszály is sújtják. A klímaváltozás előrejelzései alapján hazánkban a vízgazdálkodási szélsőségek növekedése várható, így a belvíz- és aszálykárok növekedése is. A települések ellenálló képességének javítására lehetséges intézkedéseket mutatunk be, amellyel csökkenthető a belvízi elöntések kockázata, és az aszály által okozott kár mérsékelhető. Ezeket a települési adottságok alapján, egyedi mérlegeléssel kell meghatározni.
Long-term and comparative impacts of combined sewers and municipal effluents to freshwater mussels
Creators: name: André, C
name: Vaudreuil, M A
name: Vo Duy, S
name: Sauvé, S
name: Gagné, F
Publisher: name: Invertebrate Survival Journal
Year: 2020

description: Excess rainfall events could lead to overflows and combined sewer overflows, which could threaten local mussel populations. This study sought to compare the long- term effects of combined sewer overflows and treated municipal effluents in caged Elliptio complanata mussels. Mussels were caged at 2 overflow sites, one downstream site of a major municipal effluent dispersion plume and a reference upstream site for 3 months during the summer. At the end of the exposure period, mussels were collected, analyzed for municipal contaminants (including pharmaceuticals), and effects biomarkers based on endocrine disruption (vitellogenin expression), xenobiotic detoxification (glutathione S-transferase and metallothioneins), oxidative stress/inflammation (cyclooxygenase and lipid peroxidation) and DNA damage. The data revealed that surface waters contained less pharmaceutical products than the downstream site but atrazine and its metabolite were at higher levels in overflow sites. Mussels contained elevated amounts of total heterotrophic bacteria, caffeine, acebutolol and venlafaxine at the downstream site relative to the upstream site where caffeine was higher at one of the overflow site. The levels of vitellogenin gene expression were significantly increased in both sexes of mussels caged at the downstream site only. Multivariate analysis revealed that the biomarker responses were completely separated between upstream, overflow and downstream sites. The site discrimination was based on vitellogenin, metallothioneins, DNA damage in gonad and digestive gland, gonad lipids/proteins reserves, lipid peroxidation, gonado-somatic index and condition factor. Adverse outcome pathways analysis using the power law approach revealed that most changes in the biomarkers identified by discriminant function analysis were significantly scaled to gonad energy reserves, tissue/ mussel size and loss of weight following air emersion stress. In conclusion, the toxic effects of mussels caged at overflow sites generally displayed lower responses than mussels caged downstream a treated municipal effluent suggesting that these overflows pose a lower risk than the continuous exposure to treated municipal effluent.
description: Invertebrate Survival Journal, Vol 17 No 1 (2020)
Sylvicanthon bridarollii
Creators: name: Cupello, Mario
name: Vaz-De, Fernando Z.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Sylvicanthon
Sylvicanthon bridarollii

description: Sylvicanthon bridarollii (Martínez, 1948)
Material examined
BOLIVIA: Cochabamba: 1 ♀, Chapare (FSCA, ex E.N. Kellesvig–Waering collection); 1 ♀, Chapare, 15 May 1951, no collector (FSCA, ex E.N. Kellesvig–Waering collection); 2 ♀♀, Chapare, 400 m, 5 May 1951, no collector (FSCA, ex E.N. Kellesvig–Waering collection). – Santa Cruz: 1 ♀, Ichilo, “ 3.7 km SSE Buena Vista, Hotel Flora & Fauna”, 430 m, 14–19 Oct. 2000, M.C. Thomas leg. (FSCA); 1 ♀, Ichilo, “ 3.7 km.SSE Buena Vista, Hotel Flora & Fauna”, 430 m, 14–28 Oct. 2000, B.K. Dozier leg. (FSCA); 1 ♀, Ichilo, “ 4–6 km SSE Buena, Vista Fauna & Flora Hotel”, 420–450 m, 2–12 Feb. 2000, pitfall with dung and carrion, J.E. Wappes leg. (FSCA); 2 ♂♂, Ichilo, “ 5km SSE Buena Vista, Hotel Fauna & Flora”, 17º29.935′ S, 63º39.129′ W, 440 m, 24–31 Dec. 2003, S. and J. Peck leg. (FSCA).
ECUADOR: Sucumbíos: 6 ♂♂, 1 ♀, Limoncocha, Jul. 1979, trap with human faeces, T. Ray leg. (MCZC); 1 ♂, Limoncocha, 00º24′ S, 76º36′ W, 22 Jun. 1976, Peter L. Kazan leg. (FSCA).
PERU: Huánuco: 1 ♀, Leoncio Prado, Rupa-Rupa, Tingo María, Universidad Nacional Agraria de la Selva (“Tingo María Universidad”), Dec. 1974, Martínez leg. (FSCA).
description: Published as part of Cupello, Mario & Vaz-De, Fernando Z., 2018, A monographic revision of the Neotropical dung beetle genus Sylvicanthon Halffter & Martínez, 1977 (Coleoptera: Scarabaeidae: Scarabaeinae: Deltochilini), including a reappraisal of the taxonomic history of ' Canthon sensu lato', pp. 1-205 in European Journal of Taxonomy 467 on page 204, DOI: 10.5852/ejt.2018.467, http://zenodo.org/record/3824775
"KNOWLEDGE, ATTITUDE AND PRACTICES OF PREMARITAL COUNSELING FOR SICKLE CELL DISEASE (SCD) AMONGST COUNCIL WORKERS IN  THE TUBAH, BAMENDA I, II, III AND CITY COUNCIL OF NORTH WEST CAMEROON"
Creators: name: Muluhtekwi Ignatius Nji
name: Nguemaïm Flore
name: Dr Loveline Lum Niba
name: Dr Bodzewan Emmanuel Fonyuy
name: Esoh Rene Tanwieh
name: Solomom Gyampoh
name: Lukong Jude Thaddeus Veranso
Publisher: name: Zenodo
Year: 2024
Subjects: Sickle cell disease; premarital counseling; knowledge; attitude; practice; awareness.

description: Abstract: -

Background: Cameroon has high rates of sickle cell disease (SCD) attributed to lack of awareness among the reproductive age in the country. In Cameroon, the prevalence of SCD is 18.2% for the heterozygous form and 2.3% for the homozygous (HbSS) forms.

Objective: This study determined the knowledge, attitude and practices of premarital counseling for sickle cell disease (PMCSCD) amongst Council workers of the Tubah, Bamenda I, II, III and City Council of North West Region of Cameroon, to see how this knowledge can be translated to intending couples to improve marital outcomes.

Materials and method: A community based cross sectional study design with purposive random sampling was used to select Council workers who participated in the study. Data was generated by use of semi-structured questionnaires and presented using frequency, percentages and charts. Descriptive analysis was done using statistical package for social sciences (SPSS) software version 21. Relationship between variables was assessed using Chi-Square Test. We used a P-value of <0.05 as a cut off point for statistical significance.

Results: A total of 59 respondents filled the survey. The result shows that knowledge of PMCSCD varied from one aspect to another, with an overall poor level. Attitude of respondents towards PMCSCD remained good (54.2%). Meanwhile implementation of PMCSCD in participants life was grossly inadequate (96.6%), with apparently no premarital counselor for SCD in any of the councils as reported by 83.1% of study participants. Out of the sociodemographic characteristics of interest, level of education was found to be significantly associated with knowledge (X2=17.5; P= 0.04).  The survey also found a significant association between participants attitude and sex, age group and marital status. No sociodemographic factor was found to be associated with practice.

Conclusion: Overall, council workers had poor knowledge of PMCSCD. Attitude of workers towards PMCSCD was good. Practice of PMCSCD among study participants remained poor. This suggests that council authorities should take advantage of this information and pull attention to potential areas for intervention and improvements in knowledge of man power resources especially true in relation to sickle cell disease counselor so that the knowledge can be translated to intending couples to foster better outcomes in sickle cell prevention, awareness and management.
Research Communications and Open Access to Knowledge
Creators: name: Anup Kumar Das
Publisher: name: Zenodo
Year: 2020
Subjects: Open Access, Open Science, India, South Asia, Open Science, Open Research Data

description: The presentation titled "Research Communications and Open Access to Knowledge" was delivered in a Webinar on 10th May 2020, organized by IQAC, B.B. College, Asansol, India. It covers the open access initiatives in India and the country's position in the Global South.
description: Co-organized by the Communication and Information Society of India (ICSI), National Digital Library of India (NDLI), and other organizations.
Proceedings of the Third Annual Good Roads Convention of the Boards of Supervisors of the State of New York, Held at Albany, N.Y., January 28 and 29, 1902
Creators: name: Office Of Public Road Inquiries
Publisher: name: Unknown
Year: 1902
Subjects: subject: Community/Rural/Urban Development
subject: Labor and Human Capital
subject: Marketing
subject: FOS: Economics and business
subject: Public Economics

description: From the Letter of Transmittal: I have the honor to transmit herewith the proceedings of the Third Annual Good Roads Convention of the Boards of Supervisors of the State of New York, held at Albany, N. Y., January 28 and 29, 1902. This report contains much valuable information on the road subject, and will be very useful to all who are studying the question of State aid. Many of the Southern and Western States are contemplating legislation with reference to State aid, and numerous inquiries are being made concerning the success of the plan where heretofore tried. New York being the leading State, and having applied the State-aid plan in an improved form most successfully, I have no doubt that the copious information brought out at this meeting of the boards of supervisors of the State of New York will be very interesting and beneficial to people in many of the other States. The illustrations were furnished by the office of the New York State Engineer and Surveyor.
Sylvicanthon foveiventris
Creators: name: Cupello, Mario
name: Vaz-De, Fernando Z.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Sylvicanthon
Sylvicanthon foveiventris

description: Sylvicanthon foveiventris (Schmidt, 1920)
Material examined
BRAZIL: Rio de Janeiro: 1 ♂, Itatiaia, 700 m, Feb. 1959, W. Zikan leg. (CEAH).
description: Published as part of Cupello, Mario & Vaz-De, Fernando Z., 2018, A monographic revision of the Neotropical dung beetle genus Sylvicanthon Halffter & Martínez, 1977 (Coleoptera: Scarabaeidae: Scarabaeinae: Deltochilini), including a reappraisal of the taxonomic history of ' Canthon sensu lato', pp. 1-205 in European Journal of Taxonomy 467 on page 204, DOI: 10.5852/ejt.2018.467, http://zenodo.org/record/3824775
Longing for ground in a ground(less) world: a qualitative inquiry of existential suffering
Creators: name: Bruce, Anne
name: Schreiber, Rita
name: Petrovskaya, Olga
name: Boston, Patricia
Publisher: name: BioMed Central
Year: 2016

description: Background: Existential and spiritual concerns are fundamental issues in palliative care and patients frequently articulate these concerns. The purpose of this study was to understand the process of engaging with existential suffering at the end of life. Methods: A grounded theory approach was used to explore processes in the context of situated interaction and to explore the process of existential suffering. We began with in vivo codes of participants' words, and clustered these codes at increasingly higher levels of abstractions until we were able to theorize. Results: Findings suggest the process of existential suffering begins with an experience of groundlessness that results in an overarching process of Longing for Ground in a Ground(less) World, a wish to minimize the uncomfortable or anxiety-provoking instability of groundlessness. Longing for ground is enacted in three overlapping ways: by turning toward one's discomfort and learning to let go (engaging groundlessness), turning away from the discomfort, attempting to keep it out of consciousness by clinging to familiar thoughts and ideas (taking refuge in the habitual), and learning to live within the flux of instability and unknowing (living in-between). Conclusions: Existential concerns are inherent in being human. This has implications for clinicians when considering how patients and colleagues may experience existential concerns in varying degrees, in their own fashion, either consciously or unconsciously. Findings emphasize a fluid and dynamic understanding of existential suffering and compel health providers to acknowledge the complexity of fear and anxiety while allowing space for the uniquely fluid nature of these processes for each person. Findings also have implications for health providers who may gravitate towards the transformational possibilities of encounters with mortality without inviting space for less optimistic possibilities of resistance, anger, and despondency that may concurrently arise.
Sylvicanthon genieri Cupello & Vaz-De 2018, sp. nov.
Creators: name: Cupello, Mario
name: Vaz-De, Fernando Z.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Sylvicanthon
Sylvicanthon genieri

description: Sylvicanthon genieri sp. nov.
Material examined
Paratypes
ECUADOR: Pastaza: 2 ♂♂, “ 38 km E of Baños”, 1500 m, 9 Feb. 1990, dung bait, J. Watts and R. Beard leg. (FSCA).
PERU: Huánuco: 1 ♀, Leoncio Prado, Rupa-Rupa, Tingo María, Universidad Nacional Agraria de la Selva (“Tingo María Universidad”), Dec. 1974, Martínez leg. (FSCA).
description: Published as part of Cupello, Mario & Vaz-De, Fernando Z., 2018, A monographic revision of the Neotropical dung beetle genus Sylvicanthon Halffter & Martínez, 1977 (Coleoptera: Scarabaeidae: Scarabaeinae: Deltochilini), including a reappraisal of the taxonomic history of ' Canthon sensu lato', pp. 1-205 in European Journal of Taxonomy 467 on page 204, DOI: 10.5852/ejt.2018.467, http://zenodo.org/record/3824775
EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis: 2023 update
Creators: name: Moseng, Tuva
name: Vliet Vlieland, Theodora P. M.
name: Battista, Simone
name: Beckwée, David
name: Boyadzhieva, Vladimira
name: G. Conaghan, Philip
name: Costa, Daniela
name: Doherty, Michael
name: Finney, Andrew G.
name: Georgiev, Tsvetoslav
name: Gobbo, Milena
name: Kennedy, Norelee
name: Kjeken, Ingvild
name: P B Kroon, Féline
name: Stefan Lohmander, L
name: Lund, Hans
name: Mallen, Christian D
name: Pavelka, Karel
name: A Pitsillidou, Irene
name: Rayman, Margaret P
name: Tveter, Anne-Therese
name: Vriezekolk, Johanna E
name: Wiek, Dieter
name: Zanoli, Gustavo
name: Østerås, Nina
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: Introduction Hip and knee osteoarthritis (OA) are increasingly common with a significant impact on individuals and society. Non-pharmacological treatments are considered essential to reduce pain and improve function and quality of life. EULAR recommendations for the non-pharmacological core management of hip and knee OA were published in 2013. Given the large number of subsequent studies, an update is needed. Methods The Standardised Operating Procedures for EULAR recommendations were followed. A multidisciplinary Task Force with 25 members representing 14 European countries was established. The Task Force agreed on an updated search strategy of 11 research questions. The systematic literature review encompassed dates from 1 January 2012 to 27 May 2022. Retrieved evidence was discussed, updated recommendations were formulated, and research and educational agendas were developed. Results The revised recommendations include two overarching principles and eight evidence-based recommendations including (1) an individualised, multicomponent management plan; (2) information, education and self-management; (3) exercise with adequate tailoring of dosage and progression; (4) mode of exercise delivery; (5) maintenance of healthy weight and weight loss; (6) footwear, walking aids and assistive devices; (7) work-related advice and (8) behaviour change techniques to improve lifestyle. The mean level of agreement on the recommendations ranged between 9.2 and 9.8 (0–10 scale, 10=total agreement). The research agenda highlighted areas related to these interventions including adherence, uptake and impact on work. Conclusions The 2023 updated recommendations were formulated based on research evidence and expert opinion to guide the optimal management of hip and knee OA.
Sylvicanthon proseni
Creators: name: Cupello, Mario
name: Vaz-De, Fernando Z.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Sylvicanthon
Sylvicanthon proseni

description: Sylvicanthon proseni (Martínez, 1948)
Material examined BOLIVIA: Cochabamba: 1 ♂, 1 ♀, Chapare, 400 m, 1 Oct. 1950, no collector (FSCA).
BRAZIL: Rondônia: 1 ♂, “ 62 km SW Ariquemes, near Fazenda Rancho Grande”, 3–15 Dec. 1996, pitfall with fish carrion, J.E. Eger leg. (FSCA); 2 ♂♂, 1 ♀, “ 62 km SW Ariquemes, near Fazenda Rancho Grande”, 4–16 Nov. 1997, pitfall with fish carrion, J.E. Eger leg. (FSCA).
ECUADOR: Napo: 4 ♂♂, 3 ♀♀, “ 20 km E Puerto Napo, Allinahui ” 450 m, 9–12 Jan. 1994, P.H. Sullivan leg. (FSCA); 14 ♂♂, 4 ♀♀, Limoncocha, Jul. 1979, trap with human faeces, T. Ray leg. (MCZC); 1 ♀, Limoncocha, 00º24′ S, 76º36′ W, 29 Jun. 1972, Peter L. Kazan leg. (FSCA).
PERU: Loreto: 1 ♂, “ 80 km NE Iquitos, Explorama Lodge, 1 km from Amazon River on Rio Yanamono”, 25–28 Aug. 1992, pitfall with human faeces, Castner and Skelley leg. (FSCA); 3 ♂♂, 2 ♀♀, “ 80 km NE Iquitos, Explorama Lodge, 1 km from Amazon River on Rio Yanamono”, 1–5 Sep. 1992, pitfall with human faeces, Castner and Skelley leg. (FSCA); 14 ♂♂, 8 ♀♀, “ 160 km NE Iquitos, Explornapo Camp, 2 km from Rio Napo on Rio Sucusari”, 27–31 Aug. 1992, pitfall with human faeces, J. Castner and Skelley leg. (FSCA); 1 ♀, “Explorama Lodge, 50 mi NE Iquitos on Amazon River”, 12–19 Mar. 1988, J.E. Eger leg. (FSCA); 1 ♂, 1 ♀, Iquitos, Jungle Amazon Inn, 30 Dec. 1986 – 2 Jan. 1987, M.J. Halter leg. (FSCA); 2 ♂♂, 1 ♀, “near junction of Río Moranon and Río Ucayali ”, 4.8º S, 73.5º W, 6–20 Aug. 1994, P. Skelley leg. (FSCA).
description: Published as part of Cupello, Mario & Vaz-De, Fernando Z., 2018, A monographic revision of the Neotropical dung beetle genus Sylvicanthon Halffter & Martínez, 1977 (Coleoptera: Scarabaeidae: Scarabaeinae: Deltochilini), including a reappraisal of the taxonomic history of ' Canthon sensu lato', pp. 1-205 in European Journal of Taxonomy 467 on page 205, DOI: 10.5852/ejt.2018.467, http://zenodo.org/record/3824775
From good Intentions to proven interventions : effectiveness of actions to reduce the health impacts of air pollution
Creators: name: Giles, Luisa V.
name: Barn, Prabjit
name: Künzli, Nino
name: Romieu, Isabelle
name: Mittleman, Murray A.
name: Van Eeden, Stephan
name: Allen, Ryan
name: Carlsten, Christopher Russell
name: Stieb, David M.
name: Noonan, Curtis
name: Smargiassi, Audrey
name: Kaufman, Joel D.
name: Hajat, Shakoor
name: Kosatsky, Tom
name: Brauer, Michael (Of University Of British Columbia)
Publisher: name: The University of British Columbia
Year: 2015

description: Associations between air pollution and a multitude of health effects are now well established. Given ubiquitous exposure to some level of air pollution, the attributable health burden can be high, particularly for susceptible populations. Objectives: An international multidisciplinary workshop was convened to discuss evidence of the effectiveness of actions to reduce health impacts of air pollution at both the community and individual level. The overall aim was to summarize current knowledge regarding air pollution exposure and health impacts leading to public health recommendations. Discussion: During the workshop, experts reviewed the biological mechanisms of action of air pollution in the initiation and progression of disease, as well as the state of the science regarding community and individual-level interventions. The workshop highlighted strategies to reduce individual baseline risk of conditions associated with increased susceptibility to the effects of air pollution and the need to better understand the role of exposure duration in disease progression, reversal, and adaptation. C onclusion: We have identified two promising and largely unexplored strategies to address and mitigate air pollution–related health impacts: reducing individual baseline risk of cardiovascular disease and incorporating air pollution–related health impacts into land-use decisions.
Fenton syndrome about a case and review of the literature
Creators: name: Kharraji Abdessamad
name: Jawad Amghar
name: Hamzaoui Amine
name: Omar Agoumi
name: Abdelkrim Daoudi
Publisher: name: Zenodo
Year: 2024
Subjects: Scaphoid; Fracture; Wrist dislocations; Fracture of the capitate; Fenton syndrome.

description: Summary: - Fenton's naviculo-capital syndrome or scapho-capital fracture is a very rare lesion, often overlooked. It results from high-energy wrist trauma. Its mechanism is controversial. It is most often associated with carpal dislocation. Forced extension appears to be the most frequent etiology; fracture of the scaphoid by compression makes hyperextension of the wrist possible, thus allowing contact between the posterior horn of the lunate and the proximal pole of the capitate which is fractured and tilted from 180°. The dorsal approach allowed a reduction of the capitate as well as contention by pinning the first row, independently of the second row. The scapholunate and lunaro-triquetral interosseous ligaments were intact. The anterior approach allows a good reduction of the scaphoid while preserving its vascularization. An antebrachiopalmar cast immobilization was put in place for 12 weeks. The rehabilitation lasted six months. Two years later, the Cooney functional score was good and all the fractures had healed without any intracarpal misalignment. Return to work was in the eighth months after the accident.

Conclusion: Hypertensive disorders of pregnancy (HDP) are influenced by various factors, with older maternal age and obesity being the most common. The incidence of hypertensive disorders of pregnancy varies based on race, socioeconomic status, age, and parity. Creating awareness of the risks associated with hypertensive disorders of pregnancy is essential. Pregnant women with hypertensive disorders require frequent antenatal visits to ensure appropriate outcomes.
British Columbia Nursing Leadership Institute: program evaluation report
Creators: name: MacPhee, Maura
name: Suryaprakash, Nitya
Publisher: name: British Columbia Nursing Administrative Leadership Institute
Year: 2016

description: This report covers the BC Nursing Leadership Institute (BC NLI) operational time period from March 2005 through June 2010. Over this period of time, 14 cohorts (35-40 participants per cohort) participated in BC NLI activities. Total attendance was 451 first-line nurse leaders representing every health sector (e.g., acute care, community, mental health) and every health authority within the province. This evaluative report is based upon the four major components of the BC NLI: a) a 4-day residential workshop, b) mentoring supports at practice sites, c) year-long leadership projects at practice sites, and d) an online knowledge network with a discussion forum, resources, and a facilitator or knowledge broker (KB).
IPBES First Global assessment – Supplementary materials of Chapter 1
Creators: name: IPBES
Publisher: name: Zenodo
Year: 2019

description: The supplementary materials of chapter 1 of the first global assessment:

1.2: Nature's contibutions to people

1.3 Typology of drivers

1.4 Overarching and chapter-specific questions guiding the inclusion of 'Indigenous and Local Knowledge and Practices' [ILK] and the role of Indigenous People and Local Communities [IPLCs] in the IPBES Global Assessment (GA1)

1.5 Units of Analysis

1.6 List of core indicators

1.7 List of highlighted indicators
Crystal Methamphetamine Use Among Female Street-based Sex Workers : Moving Beyond Individual-Focused Interventions
Creators: name: Shannon, K.
name: Strathdee, Steffanie A.
name: Shoveller, Jean
name: Zhang, Ruth
name: Montaner, Julio
name: Tyndall, Mark
Publisher: name: The University of British Columbia
Year: 2018

description: Given growing concern of the sexual risks associated with crystal methamphetamine use and the dearth of research characterizing the use of methamphetamine among street-based sex workers (FSWs), this study aimed to characterize the prevalence and individual, social, and structural contexts of crystal methamphetamine use among FSWs in a Canadian setting. Drawing on data from a prospective cohort, we constructed multivariate logistic models to examine independent correlates of crystal methamphetamine among FSWs over a two-year follow-up period using generalized estimating equations. Of a total of 255 street-based FSWs, 78 (32%) reported lifetime crystal methamphetamine use and 24% used crystal methamphetamine during the two-year follow-up period, with no significant associations between methamphetamine use and sexual risk patterns. In a final multivariate GEE model, FSWs who used crystal methamphetamine had a higher proportional odds of dual heroin injection (adjOR = 2.98, 95%CI: 1.35–5.22), having a primary male sex partner who procures drugs for them (adjOR = 1.79, 95%CI: 1.02–3.14), and working (adjOR = 1.62, 95%CI: 1.04–2.65) and living (adjOR = 1.41, 95%CI: 1.07–1.99) in marginalized public spaces. The findings highlight the crucial need to move beyond the individual to gender-focused safer environment interventions that mediate the physical and social risk environment of crystal methamphetamine use among FSWs.
Pew Research Center: Science, Technology, Engineering, and Math August 2017 Survey
Creators: name: Pew Research Center
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: Change in main job (1); occupation and industry (2); specialize in teaching specific subjects (3); specific occupation (3); what one subject should K to 12 schools emphasize more (1); how much do you know about K to 12 public schools (2); rate K to 12 schools in your local community (4); rate United States K to 12 schools compared to other developed nations (4); problems with science, technology, engineering, and math (STEM) education in K to 12 schools (8); reason young people don't pursue college degrees in science, technology, engineering, and math (1); liked or disliked science/math classes (6); important qualities in choosing a job (9); qualities that affect your chances of getting ahead in the job (8); respected, valued by coworkers (2); close family members who worked in STEM fields (2); career in STEM (3); perception of jobs in STEM compared to other industries (8); reasons why women are underrepresented in STEM (7); reasons why blacks and Hispanics are underrepresented in STEM (7); discrimination in technology industry (6); gender in the workplace (6); racial diversity in the workplace (11); effect of gender on your job (11); effect of race on your job (11); most effective way to recruit diverse applicants to STEM jobs (1); sexual harassment in workplace (3); vocational/technical training, certificate, or apprenticeship (1); major field in study (1); graduate degree field (1); job related to degree (2); college level science or math classes (4); first person in immediate family to attend college (1).
Interpolation of LES cloud surfaces for use in direct calculations of entrainment and detrainment
Creators: name: Dawe, Jordan T.
name: Austin, Philip H.
Publisher: name: American Meteorological Society
Year: 2011

description: Direct calculations of the entrainment and detrainment of air into and out of clouds require knowledge of the relative velocity difference between the air and the cloud surface. However, a discrete numerical model grid forces the distance moved by a cloud surface over a time step to be either zero or the width of a model grid cell. Here a method for the subgrid interpolation of a cloud surface on a discrete numerical model grid is presented. This method is used to calculate entrainment and detrainment rates for a large-eddy simulation (LES) model, which are compared with rates calculated via the direct flux method of Romps. The comparison shows good agreement between the two methods as long as the model clouds are well resolved by the model grid spacing. This limitation of this technique is offset by the ability to resolve fluxes on much finer temporal and spatial scales, making it suitable for calculating entrainment and detrainment profiles for individual clouds. Copyright 2011 American Meteorological Society (AMS). Permission to use figures, tables, and brief excerpts from this work in scientific and educational works is hereby granted provided that the source is acknowledged. Any use of material in this work that is determined to be “fair use” under Section 107 of the U.S. Copyright Act or that satisfies the conditions specified in Section 108 of the U.S. Copyright Act (17 USC §108, as revised by P.L. 94-553) does not require the AMS’s permission. Republication, systematic reproduction, posting in electronic form, such as on a web site or in a searchable database, or other uses of this material, except as exempted by the above statement, requires written permission or a license from the AMS. Additional details are provided in the AMS Copyright Policy, available on the AMS Web site located at (http://www.ametsoc.org/) or from the AMS at 617-227-2425 or copyright@ametsoc.org.
ІНФОРМАЦІЙНА БЕЗПЕКА ДЕРЖАВИ: ІДЕНТИФІКАЦІЯ СУЧАСНИХ ВИКЛИКІВ ТА ЗАГРОЗ (результати онлайн-опитування)
Creators: name: Федорович, Черниш Роман
Publisher: name: Zenodo
Year: 2020
Subjects: онлайн-опитування
соціологічне опитування
інформаційна безпека
статистичні дані
фейк
фейкова інформація
інформаційна безпека держави
fake
stop fake

description: Вже понад шість років на території України активно реалізуються різноманітні форми та методи ведення гібридної війни. Реалії сьогодення свідчать про поступовий перехід від концепції відкритого військового протистояння до намагань підірвати державність шляхом поширення тенденційної інформації в ЗМІ (в першу чергу електронних та відповідних тематичних спільнотах соціальних мереж) з метою формування у громадян антидержавницьких поглядів. Вказане досягається, зокрема, й шляхом поширення «фейкових» новин та коментарів. При цьому пересічному користувачу досить складно відрізнити фейкову інформацію від об’єктивної. Зважаючи на використання фахових знань, відповідних технічних та психологічних прийомів в процесі її підготовки та поширення, така інформація в переважній більшості випадків викликає значний суспільний резонанс та, за певних умов, здатна в короткостроковій перспективі призвести до негативних наслідків – виникнення осередків соціальної напруги і дестабілізації суспільно-політичної ситуації як в окремому регіоні, так і в державі в цілому; дискредитація країни на міжнародній арені тощо, а в довгостроковій – до поступової зміни світогляду і переконань громадян, підміни спогадів на фейкові, формування національної ідеї у вигідному для певної особи (групи осіб) ракурсі. В сучасних умовах однією із головних загроз для національного суверенітету постає проблема системного і триваючого поширення необ’єктивної та недостовірної («фейкової») інформації. Зважаючи на наявність внутрішнього та зовнішнього вектору в її розповсюдженні, наразі здійснюються певні кроки у напрямі юридично-правової регламентації поширення такої інформації, порядку обмеження доступу до неї. Беручи до уваги вищевказане, одним із головних пріоритетів для України постає питання формування дієвого національного законодавства, яке дозволить забезпечити реалізацію Конституційних прав та свобод громадян і, при цьому, буде направлено на збереження державності шляхом протидії зовнішнім та внутрішнім загрозам в інформаційній та кібернетичній сферах. З метою отримання емпіричних даних, які, зокрема, можуть бути використані при розробці пропозицій щодо удосконалення відповідного національного законодавства України, що регламентує суспільні відносини в інформаційній сфері, фахівцями Поліського національного університету було проведено тематичне анонімне онлайн-опитування громадян.
Reactive uptake kinetics of NO3 on multicomponent and multiphase organic mixtures containing unsaturated and saturated organics.
Creators: name: Xiao, Song
name: Bertram, Allan K.
Publisher: name: Royal Society of Chemistry
Year: 2012

description: We investigated the reactive uptake of NO3 (an important night-time oxidant in the atmosphere) on binary mixtures containing an unsaturated organic (methyl oleate) and saturated molecules (diethyl sebacate, dioctyl sebacate, and squalane) which we call matrix molecules. These studies were carried out to better understand the reactivity of unsaturated organics in multicomponent and multiphase atmospheric particles. For liquid binary mixtures the reactivity of methyl oleate depended on the matrix molecule. Assuming a bulk reaction, varied by a factor of 2.7, and assuming a surface reaction HSmatrixKSmatrixkSoleate varied by a factor of 3.6, where and HSmatrixKSmatrixkSoleate are constants extracted from the data using the resistor model. For solid–liquid mixtures, the reactive uptake coefficient depended on exposure time: the uptake decreased by a factor of 10 after exposure to NO3 for approximately 90 min. By assuming either a bulk or surface reaction, the atmospheric lifetime of methyl oleate in different matrices was estimated for moderately polluted atmospheric conditions. For all liquid mixtures, the lifetime was in the order of a few minutes (with an upper limit of 35 min). These lifetimes can be used as lower limits to the lifetimes in semi-solid mixtures. Our studies emphasize that the lifetime of unsaturated organics (similar to methyl oleate) is likely short if the particle matrix is in a liquid state.
Migrating Protégé to a Modern Web Stack
Creators: name: Musen, Mark
name: Hardi, Josef
name: Horridge, Matthew
Publisher: name: Zenodo
Year: 2020
Subjects: Protégé, ontology editing, knowledge graph, open source, open science

description: This presentation describes plans to enhance WebProtégé with support of the EOSS program of the Chan Zuckerberg Initiative. More information about the Protégé project is available from our website.
U-Net code for building segmentation in the deprived urban areas (slums) of Nairobi, Kenya.
Creators: name: Abascal, Angela
Publisher: name: Zenodo
Year: 2022
Subjects: building footprints
deep learning
UNET
remote sensing

description: U-Net code for building segmentation in the deprived urban areas (slums) of Nairobi, Kenya. The analysis used satellite images as input. Funding: The research pertaining to these results received financial aid from the Belgian Federal Science Policy (BELSPO) according to the agreement of subsidy no. SR/11/380.
Cellulose accessibility limits the effectiveness of minimum cellulase loading on the efficient hydrolysis of pretreated lignocellulosic substrates
Creators: name: Arantes, Valdeir
name: Saddler, J. N. (John N.), 1953-
Publisher: name: BioMed Central
Year: 2016

description: A range of lignocellulosic feedstocks (including agricultural, softwood and hardwood substrates) were pretreated with either sulfur dioxide-catalyzed steam or an ethanol organosolv procedure to try to establish a reliable assessment of the factors governing the minimum protein loading that could be used to achieve efficient hydrolysis. A statistical design approach was first used to define what might constitute the minimum protein loading (cellulases and β-glucosidase) that could be used to achieve efficient saccharification (defined as at least 70% glucan conversion) of the pretreated substrates after 72 hours of hydrolysis. The likely substrate factors that limit cellulose availability/accessibility were assessed, and then compared with the optimized minimum amounts of protein used to obtain effective hydrolysis. The optimized minimum protein loadings to achieve efficient hydrolysis of seven pretreated substrates ranged between 18 and 63 mg protein per gram of glucan. Within the similarly pretreated group of lignocellulosic feedstocks, the agricultural residues (corn stover and corn fiber) required significantly lower protein loadings to achieve efficient hydrolysis than did the pretreated woody biomass (poplar, douglas fir and lodgepole pine). Regardless of the substantial differences in the source, structure and chemical composition of the feedstocks, and the difference in the pretreatment technology used, the protein loading required to achieve efficient hydrolysis of lignocellulosic substrates was strongly dependent on the accessibility of the cellulosic component of each of the substrates. We found that cellulose-rich substrates with highly accessible cellulose, as assessed by the Simons' stain method, required a lower protein loading per gram of glucan to obtain efficient hydrolysis compared with substrates containing less accessible cellulose. These results suggest that the rate-limiting step during hydrolysis is not the catalytic cleavage of the cellulose chains per se, but rather the limited accessibility of the enzymes to the cellulose chains due to the physical structure of the cellulosic substrate.