cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2: of A whole-blood RNA transcript-based gene signature is associated with the development of CTLA-4 blockade-related diarrhea in patients with advanced melanoma treated with the checkpoint inhibitor tremelimumab
Creators: name: Friedlander, Philip
name: Wood, Kevin
name: Wassmann, Karl
name: Christenfeld, Alan
name: Bhardwaj, Nina
name: Oh, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Table S2 Differences in pre-treatment and post-treatment expression of each of the 169 genes tested between patients who developed grade 0â 1 versus grade 2â 4 diarrhea. (a) discovery dataset and (b) validation dataset. (DOCX 17 kb)
Universality of the Network and Bubble Topology in Cosmological Gravitational Simulations
Creators: name: Yess, Capp
name: Shandarin, Sergei F.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Using percolation statistics we, for the first time, demonstrate the universal character of a network pattern in the real space, mass distributions resulting from nonlinear gravitational instability of initial Gaussian fluctuations. Percolation analysis of five stages of the nonlinear evolution of five power law models reveals that all models show a shift toward a network topology if seen with high enough resolution. However, quantitatively, the shift is significantly different in different models: the smaller the spectral index ,n, the stronger the shift. On the contrary, the shift toward the "bubble" topology is characteristic only for the n <= -1 models. We find that the mean density of the percolating structures in the nonlinear density distributions generally is very different from the density threshold used to identify them and corresponds much better to a visual impression. We also find that the maximum of the number of structures (connected regions above or below a specified density threshold) in the evolved, nonlinear distributions is always smaller than in Gaussian fields with the same spectrum, and is determined by the effective slope at the cutoff frequency.
description: The paper is 26 pages long. The latex file uses aasms.sty as a style file. There are 5 figures and 2 tables included.
Ultra-broadband antireflection coatings for multijunction solar cells using dielectric nanostructures
Creators: name: Al Saleh, Yahya Husain Mohamed
Publisher: name: Imperial College London
Year: 2017

description: Optically excited geometrical Mie resonances in dielectric nanostructures can be utilised to directionally and strongly scatter light with zero loss over broadband ranges. The nanostructure (NS) shape, size, and surrounding dielectric environment affects the wavelength dependent scattering behaviour. If placed on a high index substrate the light is favourably scattered into the optically dense material. Nanostructures can also act as an optical impedance matching layer which can be utilised to design an ultra-broadband anti-reflection coating (ARC) which promises an enhanced performance for multi-junction solar cells. The challenge is to design structures that are strongly scattering with the appropriate modes to suppress reflection and leak any harvested light into the underlying substrate. In this thesis the design of dielectric nanostructures is investigated for application as an anti-reflection coating on high index substrates with the intent of application on four-junction multi-junction solar cells (4J-MJSC). By using three dimensional numerical modelling and Mie theory, materials suitable for this purpose are identified. Simulations are used to design the structures and optimise the properties of the ARC. The structures are found to be very good scatterers, however embedding them within current industry-standard coatings yield unfavourable results with higher reflections than their planar counterparts. A new design is tested and systematically varied from single planar layers to multi-layered nanostructures to investigate effects of increasing complexity of the structures. The developed coating is optimised by varying the shape, size, and pitch of structures. Multiple numerical modelling techniques are utilised and benchmarked against each other, namely: finite elements method (FEM), rigorously coupled wave analysis (RCWA), finite difference time domain (FDTD), layer optics, and Mie calculations where applicable. The new design offers low reflectivity over an ultra-broadband range that promises to improve the output of four-junction cells by up to 5.7%. Fabrication techniques are discussed and progress made towards a working sample is detailed.
Least Cost electrification options for Suriname using OnSSET
Creators: name: Raghoebarsing, Amrita
Publisher: name: Zenodo
Year: 2024
Subjects: Suriname
OnSSET
GEP

description: This presentation constitutes the outcome of a three-weeks capacity building activity on GEP-OnSSET as part of the 2024 EMP-LAC workshop. The authors collected input data, set parameters, calibrated the model, and run electrification investment scenarios for Suriname in order to explore pathways leading to the achievement of electrification targets. The results of this analysis are not conclusive, but rather the output of experimentation with the model and thus only indicative. You may contact the author(s) for more information and/or questions about the methodology, limitations, and follow-up activities of this study.
Parallel Self-Testing of the GHZ State with a Proof by Diagrams
Creators: name: Breiner, Spencer
name: Kalev, Amir
name: Miller, Carl A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum self-testing addresses the following question: is it possible to verify the existence of a multipartite state even when one's measurement devices are completely untrusted? This problem has seen abundant activity in the last few years, particularly with the advent of parallel self-testing (i.e., testing several copies of a state at once), which has applications not only to quantum cryptography but also quantum computing. In this work we give the first error-tolerant parallel self-test in a three-party (rather than two-party) scenario, by showing that an arbitrary number of copies of the GHZ state can be self-tested. In order to handle the additional complexity of a three-party setting, we use a diagrammatic proof based on categorical quantum mechanics, rather than a typical symbolic proof. The diagrammatic approach allows for manipulations of the complicated tensor networks that arise in the proof, and gives a demonstration of the importance of picture-languages in quantum information.
description: In Proceedings QPL 2018, arXiv:1901.09476
MOESM1 of Intravenous Mesenchymal Stem Cells Improve Survival and Motor Function in Experimental Amyotrophic Lateral Sclerosis
Creators: name: Uccelli, Antonio
name: Milanese, Marco
name: Principato, Maria
name: Morando, Sara
name: Bonifacino, Tiziana
name: Vergani, Laura
name: Giunti, Debora
name: Voci, Adriana
name: Carminati, Enrico
name: Giribaldi, Francesco
name: Caponnetto, Claudia
name: Bonanno, Giambattista
Publisher: name: figshare
Year: 2012
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Neuroscience
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Supplementary material, approximately 3.82 MB.
Mechanisms of resolution of inflammation in paediatric neutrophilic lung disease
Creators: name: Brown, Sarah
Publisher: name: Imperial College London
Year: 2015

description: Many paediatric airway diseases are characterised by persistent neutrophilic inflammation, which can lead to damage to the airways and lung parenchyma. One possible mechanism for the persistence of neutrophilic inflammation is failure of the normal active resolution of the inflammatory process. There is limited published literature on the role of inflammatory resolution in paediatric inflammatory lung disease. It is possible that targeting inflammatory resolution mechanisms and the ability to “switch off” inflammation may provide therapeutic targets in the future for these diseases. This thesis investigates the hypotheses that failure of mechanisms terminating acute inflammation are important in the pathophysiology of infective and inflammatory lung disease; and that the differences in prognosis between childhood inflammatory lung diseases: cystic fibrosis (CF) (both established and newly diagnosed by newborn screening (CF NBS)), bronchiectasis, primary ciliary dyskinesia (PCD) and persistent bacterial bronchitis (PBB), are related to the ability to resolve inflammation in each disease. A number of mechanisms and mediators important for inflammatory resolution are described in a cross-sectional study of bronchoalveolar lavage (BAL) and endobronchial biopsies (EBB): BAL CD25+FoxP3+ T regulatory cells by flow cytometry; annexin A1 (AnxA1) and its receptor ALX by RT-PCR of BAL and RTPCR and immunofluorescent staining of EBB; the transcription factor Lung Krüppel- Like Factor by immunofluorescent staining of EBB; BAL lipid mediators by liquid chromatography – mass spectrometry and the lipid enzyme 15-lipoxygenase by immunofluorescent staining of EBB. Findings were related to underlying diagnosis, clinical status and airway inflammatory status (BAL neutrophils, CXCL8 and IL-10). The main abnormality found was in the AnxA1 axis, where BAL AnxA1 mRNA levels were lower in neutrophilic lung disease as compared to controls. However this was related to disease severity rather than the CFTR defect. The ratio of BAL CXCL8: IL- 10 was higher in CF as compared to other neutrophilic lung diseases and thus there was evidence that the ability of IL-10 to resolve CXCL8 mediated inflammation was reduced in CF. Therefore there was some evidence for the importance of inflammatory resolution mechanisms studied in the paediatric neutrophilic airway, and limited evidence to suggest that the anti-inflammatory function of IL-10 is impaired in CF.
Additional file 1: of A whole-blood RNA transcript-based gene signature is associated with the development of CTLA-4 blockade-related diarrhea in patients with advanced melanoma treated with the checkpoint inhibitor tremelimumab
Creators: name: Friedlander, Philip
name: Wood, Kevin
name: Wassmann, Karl
name: Christenfeld, Alan
name: Bhardwaj, Nina
name: Oh, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Table S1 List of Genes with Full Name and Aliases of Each. (DOCX 27 kb)
Idealised and regional modelling study on cyclones’ sensitivity to temperature
Creators: name: Phibbs, Samuel Anthony
Publisher: name: Imperial College London
Year: 2016

description: Idealised tropical and extratropical cyclones, and a historic medicane are simulated using the Coupled-Ocean-Atmosphere-Wave-Sediment Transport Modeling System. This manuscript examines the sensitivity of: surface wind and waves to ocean temperature for tropical cyclones (TCs); precipitation to atmospheric temperature for extra-tropical cyclones; wind, waves and precipitation to simultaneous increases in atmospheric and oceanic temperature for the medicane. More intense and larger TCs, with higher waves, form when ocean temperature is increased. The maximum significant wave height increases more than the maximum wind speed for TCs up to hurricane-force wind. Above hurricane-force wind this relationship is reversed. This is explained by the wind drag coefficient dependence on wind speed. The relative increase in the footprint of high waves is considerably greater than the increase in the maximum wave height as ocean temperature is increased. This suggests a future warmer ocean will result in a large increase in the surface area of damaging waves generated by TCs. For the extratropical cyclones the footprint of extreme precipitation (total surface area where accumulated precipitation exceeds high thresholds) and the accumulation in different sized catchment areas is examined. The footprint of extreme precipitation grows considerably with temperature. When the catchment areas are ranked in order of total precipitation, super Clausius-Clapeyron behaviour of the 99th percentile is found for all the catchment sizes. This surprising result for larger catchment areas is due to spatially concentrated changes in the extreme precipitation. A more intense, significantly larger medicane generally developed when temperatures were increased. The greater area of high winds led to increases in both the maximum significant wave height and the footprint of high waves. The mean and extreme precipitation increased with temperature slightly and substantial faster than Clausius-Clapeyron scaling respectively, this was accompanied by a larger but less fragmented footprint of extreme precipitation.
title: 01_0832
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
State estimation for active distribution network
Creators: name: Nanchian, Sara
Publisher: name: Imperial College London
Year: 2015

description: The requirement of accommodating more distributed generations (DGs) at distribution voltage level has encouraged distribution network operators to utilize their feeder capacity more effectively. This requires the availability of the various network measurements such as voltages, currents, loads, voltage control settings and DG outputs. However these quantities are not directly available in the distribution network control centre. Therefore, to control voltage and power flow in the network, the estimations of these quantities are required. This consists of the monitoring and control of the network operation by application of modern distribution management system (DMS) at the primary substation. The state estimator takes all the available network measurement information, together with a parameterized network model and estimates state of the system in operational time scale. The estimator outputs are then fed into the main control functions and other asset management tools. Although the application of State Estimation (SE) is very common task at transmission system, the practical application are not common at distribution level. This is due to the fact that the operation, topology and design at distribution level differ from those at transmission level. The untransposed three-phase circuits, unbalanced loads, shorter lines with higher ratio of R/X, and the existence of discrete control options such as transformer tap positions illustrates some of those differences. These specificities have motivated this piece of research to consider some of the key issues in distribution system state estimation and to develop algorithms to tackle them. This thesis investigated in detail the criterion for identifying suitable solvers for the distribution system state estimation (DSSE) while considering the specific characteristic of the distribution network such as discrete tap position by exploring new optimization methods which are likely to be useful for practical implementation. Some of the research findings have already been disseminated through invited conference panel and IEEE journal.
title: ADCO, Cartulaire du prieuré Notre-Dame de Bonvaux, dépendant du Val-des-Ecoliers (XVe siècle), Dijon, Cart. 228 (27 H), 68 folios, 109 actes (1211-1356), f. 0013
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: cartulaire
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire du prieuré Notre-Dame de Bonvaux, dépendant du Val-des-Ecoliers (XVe siècle), Dijon, Archives départementales de la Côte-d'Or, Cart. 228 (27 H), 68 folios, 109 actes (1211-1356). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire du prieuré Notre-Dame de Bonvaux, dépendant du Val-des-Ecoliers (XVe siècle), Dijon, Archives départementales de la Côte-d'Or, Cart. 228 (27 H), 68 folios, 109 actes (1211-1356), f. 0013, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: Dijon
description: Provenance: http://www.wikidata.org/entity/Q7003
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb15250518p
description: Provenance: http://www.idref.fr/02643413X/id
description: Provenance: https://www.geonames.org/6453767
Strix Linnaeus, 1758, gen. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Strigiformes
Strigidae
Strix

description: Strix [gen. nov.]
Rostrum aduncum (absque cera) basi pennis setaceis tectum.
Caput grande auribus oculisque magnis.
Lingua bifida.
* Auriculatae.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 92, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Conformation of cellulose-based polyelectrolytes and development of microflow scattering approaches
Creators: name: Gonzalez Lopez, Carlos
Publisher: name: Imperial College London
Year: 2014

description: The work reported on this thesis is primarily a small angle neutron scattering (SANS) and rheology study of cellulose derivative polyelectrolyte Sodium Carboxymethyl Cellulose (NaCMC) in aqueous solutions. We measure, for the first time using SANS, the relevant structural length scales as a function of polymer (cp) in aqueous salt free and NaCl solutions. The intrinsic persistence length is measured by SANS to be 55 A, characteristic of a semi-flexible polymer. In salt-free solutions, the correlation length is found to scale as cp^-1/2 across the entire semi-dilute and concentrated range. Both SANS and viscosity measurements are in general agreement with scaling theory predictions for flexible polyelectrolytes in salt free solution. The crossover between the semidilute and concentrated regimes cannot be explained as arising from the overlapping of correlation and electrostatic blobs, and appears to relate to the intrinsic persistence length of the polymer. As expected, the addition of salt leads to a decrease in viscosity and an increase in the correlation length. Flexible scaling theory cannot describe the variation of these two quantities accurately, as it neglects the intrinsic rigidity of the chains. The scaling picture put forward by Odijk appears to be correct in the high salt limit, although it suffers from several approximations, namely the use of a simplified expansion factor and an inaccurate expression from the excluded volume. Once these are corrected, theory and experiment show good agreement. We finally report the combination of SANS with microfluidics, which is a useful technique to probe the soft matter dynamics under flow, and illustrate it with well-known strongly scattering liquid crystal systems, quantifying alignment through a contraction-expansion flow field. Different microfabrication techniques and materials are discussed in terms of their compatibility with SANS. Finally, we outline a roadmap for microfluidic SANS, enabling the spatiotemporal investigation of conformational changes under flow, focusing on low scattering systems, including NaCMC in solution.
Glycoproteomic research using mass spectrometry
Creators: name: Bouche, Laura
Publisher: name: Imperial College London
Year: 2017

description: The development of problem-specific mass spectrometric (MS) glycoproteomic strategies has allowed the discovery of previously unknown protein glycosylation in both eukaryotic and prokaryotic organisms. The research in this thesis focuses on the identification and structural characterisation of novel glycan structures in ADAMTS13 and Clostridium difficile. ADAMTS13 is a large multi-domain protein which regulates thrombogenesis by cleavage of the adhesive blood glycoprotein, VWF, so generating smaller less thrombogenic fragments. Glycoproteomic strategies were employed to investigate a secretion-enhancing mutant by comparing the O-glycome of wild type (WT) with synonymous substitution, P118P, and a non-synonymous control, P118F. Identical post-translational modifications (PTMs) but several novel PTMs were discovered in ADAMTS13 including TSR1 O-glycosylation, C-mannosylation of W387 and DiSialyl Core-1 O-glycosylation of S1170. Clostridium difficile is one of the main organisms responsible for morbidity in hospitalised patients, and is the etiological agent of antibiotic-associated diarrhoea and pseudomembranous colitis. The C.difficile cell wall is surrounded by an S-layer composed of two proteins, high molecular weight (HMW) and low molecular weight (LMW) SLPs. 12 slpA gene cassettes have been recently described and cassette-11 carries an insert containing 19 ORFs. Combining different biochemical and ES- and MALDI-MS approaches, including the ETD technique, with genetic experiments, it was demonstrated that LMW SLP in strain Ox247 is glycosylated with a surprisingly large linear pentose-branched oligosaccharide of more than forty sugar residues, and a collaborative NMR study suggests a Phospho- and Acetyl- substituted non-reducing terminal rhamnose. Analysing different C.difficile hypervirulent strains, novel flagellar sulphonated peptidylamido-glycan structures not previously observed in sugar or amino acid chemistry were identified. High resolution mass measurement and negative-ion nanospray MS/MS of cone-voltage-induced fragment ions were crucial in allowing the discovery of a unique terminal Taurine (aminoethyl-sulphonic acid) peptidylamidoglycan unit which could provide a novel strategy to escape the immune system, by the C.difficile becoming more virulent.
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 494
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 494, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 494, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
A Theory of Non-Local Mixing Length Convection. III. Comparing Theory and Numerical Experiment
Creators: name: Grossman, Scott
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We solve the nonlocal convection equations. The solutions for four model problems are compared with results of GSPH simulations. In each case we test two closure schemes: 1) where third moments are defined by the diffusion approximation; and 2) where the full third moment equations are used and fourth moments are defined by a modified form of the quasi-normal approximation. In overshooting models, the convective flux becomes negative shortly after the stability boundary. The negative amplitude remains small, and the temperature gradient in the overshooting zone has nearly the radiative value. Turbulent velocities decay by a factor of $e$ after $0.5$--$1.5\ell$, depending on the model, where $\ell$ is the mixing length. Turbulent viscosity is more important than negative buoyancy in decelerating overshooting fluid blobs. These predictions are consistent with helioseismology.
description: 36 pages, plain TeX, email for figures, submitted to MNRAS
Model-based clustering for identifying disease-associated SNPs in case-control genome-wide association studies
Creators: name: Xu, Yan
name: Xing, Li
name: Su, Jessica
name: Zhang, Xuekui
name: Qiu, Weiliang
Publisher: name: arXiv
Year: 2018
Subjects: subject: Methodology (stat.ME)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Genome-wide association studies (GWASs) aim to detect genetic risk factors for complex human diseases by identifying disease-associated single-nucleotide polymorphisms (SNPs). The traditional SNP-wise approach along with multiple testing adjustment is over-conservative and lack of power in many GWASs. In this article, we proposed a model-based clustering method that transforms the challenging high-dimension-small-sample-size problem to low-dimension-large-sample-size problem and borrows information across SNPs by grouping SNPs into three clusters. We pre-specify the patterns of clusters by minor allele frequencies of SNPs between cases and controls, and enforce the patterns with prior distributions. In the simulation studies our proposed novel model outperform traditional SNP-wise approach by showing better controls of false discovery rate (FDR) and higher sensitivity. We re-analyzed two real studies to identifying SNPs associated with severe bortezomib-induced peripheral neuropathy (BiPN) in patients with multiple myeloma (MM). The original analysis in the literature failed to identify SNPs after FDR adjustment. Our proposed method not only detected the reported SNPs after FDR adjustment but also discovered a novel BiPN-associated SNP rs4351714 that has been reported to be related to MM in another study.
Strong Correlation Between Noise Features at Low Frequency and the Kilohertz QPOs in the X-Ray Binary 4U 1728-34
Creators: name: Ford, E. C.
name: van der Klis, M.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We study the timing properties of the low mass X-ray binary 4U 1728-34 using recently released data from the Rossi X-Ray Timing Explorer. This binary, like many others with accreting neutron stars, is known to exhibit strong quasi-periodic oscillations (QPOs) of its X-ray flux near 1 kHz. In addition to the kilohertz QPOs, the Fourier power spectra show a broken power law noise component, with a break frequency between 1 and 50 Hz, and a Lorentzian between 10 and 50 Hz. We find that the frequencies of the break and the low-frequency Lorentzian are well correlated with the frequencies of the kilohertz QPOs. The slope of the correlation is similar to that expected if the oscillations are due to relativistic frame dragging (Lense-Thirring precession) in the inner accretion disk (Stella & Vietri 1998). The correlation is also nearly identical to the one found in Z-sources between the the well known QPOs on the horizontal branch and the kilohertz QPOs, suggesting that the low frequency oscillations are a similar phenomenon in these sources. The frequency of the break in the power spectra is also correlated with the frequencies of the kilohertz QPOs. As previously noted for the similar binaries 4U 1608-50 and 4U 1705-44, this broken power law component closely resembles that of black hole candidates in the low state, where the break frequency is taken as an indicator of mass accretion rate. The relation between break frequency and kilohertz QPO frequency thus provides additional proof that the frequency of the kilohertz QPOs increases with mass accretion rate.
description: ApJL in press, see the 'QPO page' at http://www.astro.uva.nl/ecford/qpos.html
Least-cost technology analysis for electricity access in Ecuador
Creators: name: FALCON, ALEXANDRA
Publisher: name: Zenodo
Year: 2024

description: The Open Source Spatial Electrification Toolkit (OnSSET) plays a vital role in shaping Ecuador's optimal electrification strategy, aligning with sustainable development goals. Utilizing geospatial tools and a comprehensive dataset, OnSSET models cost-effective electrification options for urban and rural areas by 2030 and 2050. Results highlight significant growth in technology, emphasizing the importance of the existing electrical grid and extensions, with a focus on PV-based mini-grids in unserved areas. In the Galápagos Islands, where 83.6% of energy relies on fossil fuels, the study recommends exploring diverse electricity generation systems and addressing implementation challenges. OnSSET emerges as a crucial resource for informed decision-making, bridging energy research with global planning and guiding Ecuador toward a sustainable energy future.
MOESM1 of CSE1L, a Novel Microvesicle Membrane Protein, Mediates Ras-Triggered Microvesicle Generation and Metastasis of Tumor Cells
Creators: name: Ching-Fong Liao
name: Lin, Shu-Hui
name: Hung-Chang Chen
name: Cheng-Jeng Tai
name: Chun-Chao Chang
name: Li-Tzu Li
name: Yeh, Chung-Min
name: Kun-Tu Yeh
name: Chen, Ying-Chun
name: Tsu-Han Hsu
name: Shing-Chuan Shen
name: Woan-Ruoh Lee
name: Jeng-Fong Chiou
name: Shue-Fen Luo
name: Ming-Chung Jiang
Publisher: name: figshare
Year: 2012
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Supplementary material, approximately 2.71 MB.
Direct Experimental Access to the Nonadiabatic Initial Momentum Offset upon Tunnel Ionization
Creators: name: Eckart, S.
name: Fehre, K.
name: Eicke, N.
name: Hartung, A.
name: Rist, J.
name: Trabert, D.
name: Strenger, N.
name: Pier, A.
name: Schmidt, L. Ph. H.
name: Jahnke, T.
name: Schöffler, M. S.
name: Lein, M.
name: Kunitski, M.
name: Dörner, R.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We report on the non-adiabatic offset of the initial electron momentum distribution in the plane of polarization upon single ionization of argon by strong field tunneling and show how to experimentally control the degree of non-adiabaticity. Two-color counter- and co-rotating fields (390 and 780 nm) are compared to show that the non-adiabatic offset strongly depends on the temporal evolution of the laser electric field. We introduce a simple method for the direct access to the non-adiabatic offset using two-color counter- and co-rotating fields. Further, for a single-color circularly polarized field at 780 nm we show that the radius of the experimentally observed donut-like distribution increases for increasing momentum in the light propagation direction. Our observed initial momentum offsets are well reproduced by the strong-field approximation (SFA). A mechanistic picture is introduced that links the measured non-adiabatic offset to the magnetic quantum number of virtually populated intermediate states.
description: 6 pages, 4 figures
Excessive Noise as a Test for Many-Body Localization
Creators: name: Tamir, I.
name: Levinson, T.
name: Gorniaczyk, F.
name: Doron, A.
name: Lieb, J.
name: Shahar, D.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Recent experimental reports suggested the existence of a finite-temperature insulator in the vicinity of the superconductor-insulator transition. The rapid decay of conductivity over a narrow temperature range was theoretically linked to both a finite-temperature transition to a many-body-localized state, and to a charge-Berezinskii Kosterlitz Thouless transition. Here we report of low-frequency noise measurements of such insulators to test for many body localization. We observed a huge enhancement of the low-temperatures noise when exceeding a threshold voltage for nonlinear conductivity and discuss our results in light of the theoretical models.
description: 5 pages, 4 figures
Strix bubo Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Strigiformes
Strigidae
Strix
Strix bubo

description: Strix bubo [spec. nov.]
S. capite auriculato, corpore ruffo. Fn. svec. 45.
Bubo. Bell. av. 25. a. Gesn. av. 234. Aldr. orn. l. 8. c. 2. Will. orn. 62. Alb. av. 2. p. 9. t. 9. Frisch. av. t. 93.
Habitat in Europa.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 92, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
The application of autofluorescence lifetime metrology to the study of heart failure models and heart disease
Creators: name: Dyer, Benjamin Thomas
Publisher: name: Imperial College London
Year: 2016

description: Autofluorescence spectroscopy offers a promising label-free approach to characterise biological samples and has already shown diagnostic potential in a number of medical applications, although study of myocardium has been relatively limited. A number of myocardial molecules display autofluorescence, including those involved in energetics, e.g. NADH and flavoproteins, as well as structural molecules, e.g. collagen. This thesis discusses the application of a custom-built single point fibre-optic probe-based instrumentation for time-resolved spectrofluorometry utilising spectrally resolved time-correlated single photon counting detection (TCSPC) and white light reflectometry to the investigation of models of heart failure, both ex vivo and in vivo. Heart failure (HF) is a pathophysiological state in which an abnormality of cardiac function causes failure of the heart to pump blood at a rate commensurate with the requirements of the metabolising tissues. It affects 1-2% of the population rising to greater than 10% aged over 70 years. Despite recent therapeutic advances, annualized mortality can still approach 10%. HF results from a myocardial injury (e.g. myocardial infarction, chemotherapy) causing loss of myocytes, and maladaptive changes in surviving myocytes and extracellular matrix by ‘pathological remodelling’. That HF is characterized by structural and energetic changes was the principal motivation for the creation of an instrument to investigate changes in myocardial autofluorescence signature in disease states in vivo. If the signatures associated with known pathological diagnoses could be ascertained, such a technique could perform ‘virtual biopsy’ to aid diagnosis. This thesis describes the application of autofluorescence technique to an ex vivo Langendorff-heart to characterise the changes in autofluorescence signature with controlled insults of glucose deprivation and hypoxia. Additionally, it reports for the first-time the characterization of the autofluorescence lifetime signature in vivo at different time points in an established rat post-myocardial infarction heart failure. The thesis describes development of in vivo intravenous doxorubicin chemotherapy-cardiomyopathy heart failure model (DOX-HF) and subsequent characterization of in vivo autofluorescence signature. This investigation prompted development of a clinically viable instrument and the progress to date is described.
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°ÑÐµÐ»ÑÑÐºÐ¾Ð³Ð¾ Ð¸Ð½ÑÐµÑÑÐµÐ¹ÑÐ° Ð´Ð»Ñ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÐºÐ»Ð°Ð´ÑÐºÐ¸Ð¼Ð¸ Ð·Ð°Ð¿Ð°ÑÐ°Ð¼Ð¸
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Development of a user interface for an automated inventory management system
Creators: name: ÐÑÑÐ»Ð¾Ð², ÐÐ»Ð°Ð´Ð¸ÑÐ»Ð°Ð²
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2025
Subjects: ÑÑÑÐ½Ð¾ÑÑÑ-ÑÐ²ÑÐ·Ñ
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idef0
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entity-connection
1c:enterprise 8
tmc
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dbms
er-models

description: Ð Ð°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¸ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐµ ÑÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð½ÑÑ Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼Ð¾Ð² Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½ÑÑ Ð¿ÑÐ¾ÑÐµÑÑÐ¾Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð² Ð¿ÑÐ¾ÑÐµÐ´ÑÑÐ°Ñ ÑÑÐµÑÐ° Ð½Ð° ÑÐºÐ»Ð°Ð´Ð°Ñ ÐÑÐ½Ð¾Ð²Ð½ÑÐµ Ð·Ð°Ð´Ð°ÑÐ¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ: 1. ÐÐ½Ð°Ð»Ð¸Ð· Ð¿ÑÐµÐ´Ð¼ÐµÑÐ½Ð¾Ð¹ Ð¾Ð±Ð»Ð°ÑÑÐ¸, Ð¿Ð¾ÑÑÐ°Ð½Ð¾Ð²ÐºÐ° Ð·Ð°Ð´Ð°ÑÐ¸ Ð¸ Ð²ÑÐ´ÐµÐ»ÐµÐ½Ð¸Ð¸ Ð±Ð¸Ð·Ð½ÐµÑ-Ð¿ÑÐ¾ÑÐµÑÑÐ¾Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸. 2. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¼Ð¾Ð´ÐµÐ»Ð¸ ÑÐ°Ð±Ð¾ÑÑ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ. 3. Ð ÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Â«Ð£ÑÐµÑÐ° ÑÐ¾Ð²Ð°ÑÐ½Ð¾-Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»ÑÐ½ÑÑ ÑÐµÐ½Ð½Ð¾ÑÑÐµÐ¹Â». 4. Ð¢ÐµÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÑÐ¸ÑÑÐµÐ¼Ñ, Ð¿ÑÑÐµÐ¼ Ð¿ÑÐ¾Ð²ÐµÑÐºÐ¸ Ð²ÑÐµÐ³Ð¾ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»Ð° Ð¸ Ð¿ÑÐ¾Ð²ÐµÑÐºÐ° ÐµÐ³Ð¾ Ð¿ÑÐ°Ð²Ð¸Ð»ÑÐ½Ð¾ÑÑÐ¸. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ ÑÐ°Ð±Ð¾ÑÑ Ð±ÑÐ»Ð° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð° ÑÐ¸ÑÑÐµÐ¼Ð° Â«Ð£ÑÐµÑÐ° ÑÐ¾Ð²Ð°ÑÐ½Ð¾-Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»ÑÐ½ÑÑ ÑÐµÐ½Ð½Ð¾ÑÑÐµÐ¹Â». Ð¡Ð¾Ð·Ð´Ð°Ð½Ð½Ð°Ñ ÑÐ¸ÑÑÐ¾Ð²Ð°Ñ ÑÐ¸ÑÑÐµÐ¼Ð° Ð¾ÑÐ²Ð°ÑÑÐ²Ð°ÐµÑ ÑÐ¸ÑÐ¾ÐºÐ¸Ð¹ ÑÐ¿ÐµÐºÑÑ Ð·Ð°Ð´Ð°Ñ Ð¿Ð¾ ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñ ÑÐºÐ»Ð°Ð´ÑÐºÐ¸Ñ Ð¾ÑÑÐ°ÑÐºÐ¾Ð² Ð¸ Ð¾ÑÐ¾ÑÐ¼Ð»ÐµÐ½Ð¸Ñ ÐºÐ¾Ð¼Ð¼ÐµÑÑÐµÑÐºÐ¾Ð¹ Ð´Ð¾ÐºÑÐ¼ÐµÐ½ÑÐ°ÑÐ¸Ð¸. ÐÐ»Ð°ÑÑÐ¾ÑÐ¼Ð° Ð·Ð½Ð°ÑÐ¸ÑÐµÐ»ÑÐ½Ð¾ ÑÐ»ÑÑÑÐ°ÐµÑ ÐºÐ°ÑÐµÑÑÐ²Ð¾ Ð¸Ð½Ð²ÐµÐ½ÑÐ°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ Ð¸ ÑÐ°ÑÑÐ¸ÑÑÐµÑ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÐ¸ Ð°Ð½Ð°Ð»Ð¸ÑÐ¸ÐºÐ¸ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ.
description: The work is devoted to the research and development of improved algorithms for the organizations production processes in warehouse accounting procedures Main objectives of the study: 1. Analysis of the subject area, setting the task and identifying the organizations business processes. 2. Developing a model of application operation. 3. Implementation of the management system "Accounting of inventory items". 4. Testing the system by checking all functionality and verifying its correctness. As a result of the work, the "Inventory Accounting" system was developed. The created digital system covers a wide range of tasks for monitoring warehouse balances and preparing commercial documentation. The platform significantly improves the quality of inventory and expands the capabilities of enterprise analytics.
Труды Кольского научного центра РАН, Выпуск 12019
Creators: name: Кольский научный центр Российской академии наук
Publisher: name: Труды Кольского научного центра РАН
Year: 2019

description: , Выпуск 12019
description: В 2010-м году президиум КНЦ РАН принял решение о возвращении к уже имевшейся в предыдущие годы практике издания «Трудов Кольского научного центра РАН» в виде специализированных тематических научных журналов по основным направлениям научно-исследовательской деятельности учреждений Центра.
MOESM1 of Female Mice Are More Susceptible to Nonalcoholic Fatty Liver Disease: Sex-Specific Regulation of the Hepatic AMP-Activated Protein Kinase-Plasminogen Activator Inhibitor 1 Cascade, but Not the Hepatic Endotoxin Response
Creators: name: Spruss, Astrid
name: Henkel, Janin
name: Giridhar Kanuri
name: Blank, Daniela
name: PĂźschel, Gerhard
name: Bischoff, Stephan
name: Bergheim, Ina
Publisher: name: figshare
Year: 2012
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplementary material, approximately 341 KB.
Discovery of Recent Star Formation in the Extreme Outer Regions of Disk Galaxies
Creators: name: Ferguson, Annette
name: Wyse, Rosemary
name: Gallagher, Jay
name: Hunter, Deidre
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present deep Halpha images of three nearby late-type spiral galaxies (NGC628, NGC1058 and NGC6946), which reveal the presence of HII regions out to, and beyond, two optical radii (defined by the 25th B-band isophote). The outermost HII regions appear small, faint and isolated, compared to their inner disk counterparts, and are distributed in organized spiral arm structures, likely associated with underlying HI arms and faint stellar arms. The relationship between the azimuthally--averaged Halpha surface brightness (proportional to star formation rate per unit area) and the total gas surface density is observed to steepen considerably at low gas surface densities. We find that this effect is largely driven by a sharp decrease in the covering factor of star formation at large radii, and not by changes in the rate at which stars form locally. An azimuthally--averaged analysis of the gravitational stability of the disk of NGC6946 reveals that while the existence of star formation in the extreme outer disk is consistent with the Toomre-Q instability model, the low rates observed are only compatible with the model when a constant gaseous velocity dispersion is assumed. We suggest that observed behaviour could also be explained by a model in which the star formation rate has an intrinsic dependence on the azimuthally-averaged gas volume density, which decreases rapidly in the outer disk due to the vertical flaring of the gas layer.
description: 10 pages, 2 embedded postscript files, 3 jpeg images; accepted for publication in ApJ Letters
MPEC 2024-D73 : 2024 DV
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 DV

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: AN, Registre des écrous du Châtelet, Y5266, f. p1000850
Creators: name: Claustre, Julie
name: Nationales, Archives
name: Archives Nationales
name: Claustre, Julie
name: ArchivesNationales/J.CLAUSTRE/H.REGAZZI/2020
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Châtelet
subject: registre

description: Registre des écrous du Châtelet, Archives Nationales, Y5266. Numérisation en mode image.
description: Bibliographic citation: Archives Nationales, Registre des écrous du Châtelet, Y5266, f. p1000850
Maintenance of the last step of the cold chain: on-farm refrigerator storage and performance
Creators: name: Fallness, Cynthia A.
name: Rollin, Emmanuel
name: Heins, Bradley D.
name: Berghaus, Roy D.
Publisher: name: The Bovine Practitioner
Year: 2022
Subjects: livestock vaccines
cold chain
refrigerator monitoring

description: Maintenance of the cold chain post-manufacturing for livestock vaccines is the most important way to ensure maximum product efficacy and safety. Often, it is unknown if refrigerators used for farm storage are operating in the recommended temperature interval (RTI) for vaccine storage of 36°F to 46°F (2°C to 8°C), and whether or not they are able to maintain those temperatures as the ambient room temperature changes. In order to evaluate the performance of different styles of refrigerators on dairy farms and veterinary clinics in the southeast United States, a convenience sample of 20 refrigerators was selected for the placement of digital data loggers to monitor the internal refrigerator and ambient temperatures over 5 months from July to November 2021. The percentage of time that refrigerators spent outside the RTI ranged from 0% to 80% with a median of 22%. The percentage of time outside the RTI was significantly greater for household refrigerators (37%) compared to commercial refrigerators (2.2%), while mini-refrigerators (27%) were intermediate. The estimated mean daily temperature range (MDTR) of household refrigerators (9.5°F, 5.3°C) was also significantly greater than that for commercial (5.4°F, 3°C) or mini (5.8°F, 3.2°C) refrigerators. Implications of the study show the necessity for proper temperature monitoring, staff training and record keeping to ensure vaccine efficacy and product safety, and ultimately improve animal health and productivity.
description: The Bovine Practitioner, Vol. 56 No. 2 (2022)