cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MAW : the reproducible Metabolome Annotation Workflow for untargeted tandem mass spectrometry
Creators: name: Zulfiqar, Mahnoor
name: Gadelha, Luiz
name: Steinbeck, Christoph
name: Sorokina, Maria
name: Peters, Kristian
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 570

description: Mapping the chemical space of compounds to chemical structures remains a challenge in metabolomics. Despite the advancements in untargeted liquid chromatography-mass spectrometry (LC–MS) to achieve a high-throughput profile of metabolites from complex biological resources, only a small fraction of these metabolites can be annotated with confidence. Many novel computational methods and tools have been developed to enable chemical structure annotation to known and unknown compounds such as in silico generated spectra and molecular networking. Here, we present an automated and reproducible Metabolome Annotation Workflow (MAW) for untargeted metabolomics data to further facilitate and automate the complex annotation by combining tandem mass spectrometry (MS2) input data pre-processing, spectral and compound database matching with computational classification, and in silico annotation. MAW takes the LC-MS2 spectra as input and generates a list of putative candidates from spectral and compound databases. The databases are integrated via the R package Spectra and the metabolite annotation tool SIRIUS as part of the R segment of the workflow (MAW-R). The final candidate selection is performed using the cheminformatics tool RDKit in the Python segment (MAW-Py). Furthermore, each feature is assigned a chemical structure and can be imported to a chemical structure similarity network. MAW is following the FAIR (Findable, Accessible, Interoperable, Reusable) principles and has been made available as the docker images, maw-r and maw-py. The source code and documentation are available on GitHub (https://github.com/zmahnoor14/MAW). The performance of MAW is evaluated on two case studies. MAW can improve candidate ranking by integrating spectral databases with annotation tools like SIRIUS which contributes to an efficient candidate selection procedure. The results from MAW are also reproducible and traceable, compliant with the FAIR guidelines. Taken together, MAW could greatly facilitate automated metabolite characterization in diverse fields such as clinical metabolomics and natural product discovery.
CYTOTOXICITY OF DICLOFENAC AND ETHYLENEDIAMINE COMPLEXES WITH Ni2+, Cu2+ and Zn2+
Creators: name: Obidova, N.
name: Ziyaev, M.
name: Ashurov, J.
name: Khodjaniyazov Kh.
Publisher: name: Norwegian Journal of Development of the International Science
Year: 2020
Subjects: diclofenac
metal complex
organic salt
cytotoxicity
Ni2+
Cu2+
Zn2+ cations

description: Recently it was synthesized an organic salt of diclofenac with ethylenediamine and complex compounds of these two ligands and metal cations Ni2+, Cu2+ and Zn2+, the structures of which were confirmed by the X-ray analyses. Investigation on cytotoxicity of the complexes against to HeLa cells showed 2.0-4.4 times efficacy then parent diclofenac. Once again proven that complexation with metals leads to an enhancement of the activity of the pharmaceutical drug.
Quantum mechanics of a free particle from properties of the Dirac delta function
Creators: name: Bondar, Denys I.
name: Lompay, Robert R.
name: Liu, Wing-Ki
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Based on the assumption that the probability density of finding a free particle is independent of position, we infer the form of the eigenfunction for the free particle, $\bra{x} p > = \exp(ipx/\hbar)/\sqrt{2π\hbar}$. The canonical commutation relation between the momentum and position operators and the Ehrenfest theorem in the free particle case are derived solely from differentiation of the delta function and the form of $\bra{x} p >$.
description: 3 pages
The impact of upright posture on left ventricular deformation in athletes
Creators: name: Kandels, Joscha
name: Metze, M.
name: Hagendorff, Andreas
name: Marshall, R. P.
name: Hepp, P.
name: Laufs, Ulrich
name: Stöbe, S.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Besides LV ejection fraction (LVEF), global longitudinal strain (GLS) and global myocardial work index (GWI) are increasingly important for the echocardiographic assessment of left ventricular (LV) function in athletes. Since exercise testing is frequently performed on a treadmill, we investigated the impact of upright posture on GLS and GWI. In 50 male athletes (mean age 25.7 ± 7.3 years) transthoracic echocardiography (TTE) and simultaneous blood pressure measurements were performed in upright and left lateral position. LVEF (59.7 ± 5.3% vs. 61.1 ± 5.5%; P = 0.197) was not affected by athletes’ position, whereas GLS (− 11.9 ± 2.3% vs. − 18.1 ± 2.1%; P < 0.001) and GWI (1284 ± 283 mmHg% vs. 1882 ± 247 mmHg%; P < 0.001) were lower in upright posture. Longitudinal strain was most frequently reduced in upright posture in the mid-basal inferior, and/or posterolateral segments. Upright posture has a significant impact on LV deformation with lower GLS, GWI and regional LV strain in upright position. These findings need to be considered when performing echocardiography in athletes.
Two birds with one stone: can public financial support help firms to address financial and non-financial obstacles to research and innovation?
Creators: name: Perez Alaniz, Mauricio
name: Lenihan, Helena
name: Doran, Justin
name: Roper, Stephen
Publisher: name: University of Limerick
Year: 2025
Subjects: classificationCode: 38
subject: Economics

description: Financial, knowledge and market obstacles can restrict firm-level research and innovation (R&I). Public financial support for R&I can clearly help firms that face financial obstacles to invest in R&I. Building on the literature concerning the learning effects of public financial support for R&I, and using a novel combination of administrative and innovation-survey data, we demonstrate for the first time, that such public financial support also results in more R&I in firms that face knowledge and market obstacles. Despite this, however, public financial support for R&I does not reduce the importance that firms attach to their financial and knowledge obstacles. Moreover, it increases the importance that firms attach to their market obstacles. This suggests that while effective at helping firms to increase their R&I activities, addressing firms’ financial and non-financial obstacles may require additional policy interventions, alongside public financial support for R&I. Our study offers novel insights for theory and policy
DYNAMICS OF INFLAMMATORY MEDIATORS IN CONDITIONS OF SUBSTANCE P BLOCK
Creators: name: Shevchenko O.
name: Sych, V.
Publisher: name: Norwegian Journal of Development of the International Science
Year: 2020
Subjects: interleukin-6
secondary chronic inflammation
substance P
tumor necrosis factor-α

description: With the aim to determine the features of the concentration of tumor necrosis factor-α, interleukin-6 in the blood in carrageenan secondary chronic inflammation against the background of blockade of substance P an experimental prospective controlled randomized study was performed on 132 WAG rats in series of 6 rats each in the natural course and using a pharmacological aprepitant praparation – inhibitor of NK-1R in the control and simulated inflammation series for 6 hours, as well as 1, 2, 3, 5, 7, 10, 14, 21, 28 days. the peculiarities of the concentration of tumor necrosis factor-α, interleukin-6 in the blood in carrageenan secondary chronic inflammation on the background of blockade of substance P have been developed.
Empirical analysis of brittle rock mass failure in response to undercut advance for preventive support maintenance
Creators: name: McMillan, Robert
Publisher: name: University of British Columbia
Year: 2022

description: Stress-induced brittle fracturing of massive rock near a highly stressed excavation boundary causes the volume of the rock mass to increase, known as bulking. Excessive bulking represents a safety hazard for underground workers and can cause costly production delays at underground mining operations. For block and panel cave mines, these project risks are exacerbated during cave establishment due to large-scale stress changes from undercutting and cave propagation that redistribute and magnify stresses near excavations that are critical for production. The research presented in this thesis aims to improve the identification, analysis of, and means to mitigate adverse brittle rock mass behavior in high-stress environments. This research makes use of a unique historical geotechnical monitoring database collected by PTFI from the DMLZ panel cave mine. The geotechnical monitoring database represents an initial step towards best practices for data collection at deep cave mines operating in high-stress environments during the ramp-up period. Borehole camera surveys supplemented by multi-point borehole extensometer instruments have been used to determine the depth of stress-induced brittle fracture damage in the drawpoint pillar walls. Convergence measurements and LiDAR data are used to characterize the corresponding rock mass bulking. The results presented show that the compilation and interpretation of historical monitoring data can be used to identify the long-term depth of stress-induced fracturing and bulking trends in response to undercut advance. The integration of these long-term trends shows that direct measures of stress-induced fracturing provide an early indication of excavations vulnerable to bulking. Empirical methods are used to relate the depth of stress-fractured rock to the intact rock strength and distance from the cave front. Based on the relationships derived, a methodology for generating an empirical two-factor susceptibility map to estimate the depth of stress-induced fracturing across an extraction level footprint is presented. LiDAR scanning is used to show that it is an effective method for capturing the onset of bulking and anticipating local areas that are likely to experience greater deformation demand as bulking progresses. Proactive and strategic geotechnical monitoring based on long-term depth of stress-induced fracturing trends is proposed to assist with preventive support maintenance practices.
Degree of randomness: numerical experiments for astrophysical signals
Creators: name: Gurzadyan, V. G.
name: Ghahramanyan, T.
name: Sargsyan, S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Astrophysical and cosmological signals such as the cosmic microwave background radiation, as observed, typically contain contributions of different components, and their statistical properties can be used to distinguish one from the other. A method developed originally by Kolmogorov is involved for the study of astrophysical signals of randomness of various degrees. Numerical performed experiments based on the universality of Kolmogorov distribution and using a single scaling of the ratio of stochastic to regular components, reveal basic features in the behavior of generated signals also in terms of a critical value for that ratio, thus enable the application of this technique for various observational datasets
description: 6 pages, 9 figures; Europhys.Letters; to match the published version
Role of dopamine in the heart in health and disease
Creators: name: Neumann, Joachim
name: Hofmann, Britt
name: Dhein, Stefan
name: Gergs, Ulrich
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Dopamine has effects on the mammalian heart. These effects can include an increase in the force of contraction, and an elevation of the beating rate and the constriction of coronary arteries. Depending on the species studied, positive inotropic effects were strong, very modest, or absent, or even negative inotropic effects occurred. We can discern five dopamine receptors. In addition, the signal transduction by dopamine receptors and the regulation of the expression of cardiac dopamine receptors will be of interest to us, because this might be a tempting area of drug development. Dopamine acts in a species-dependent fashion on these cardiac dopamine receptors, but also on cardiac adrenergic receptors. We will discuss the utility of drugs that are currently available as tools to understand cardiac dopamine receptors. The molecule dopamine itself is present in the mammalian heart. Therefore, cardiac dopamine might act as an autocrine or paracrine compound in the mammalian heart. Dopamine itself might cause cardiac diseases. Moreover, the cardiac function of dopamine and the expression of dopamine receptors in the heart can be altered in diseases such as sepsis. Various drugs for cardiac and non-cardiac diseases are currently in the clinic that are, at least in part, agonists or antagonists at dopamine receptors. We define the research needs in order to understand dopamine receptors in the heart better. All in all, an update on the role of dopamine receptors in the human heart appears to be clinically relevant, and is thus presented here.
Additional file 1 of Prevalence and predictors of workplace violence against emergency physicians in China: a cross-sectional study
Creators: name: Yan, Shijiao
name: Feng, Jing
name: Gan, Yong
name: Wang, Rixing
name: Song, Xingyue
name: Luo, Zhiqian
name: Han, Xiaotong
name: Lv, Chuanzhu
Publisher: name: figshare
Year: 2023
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 1: Table S1. Distribution of provinces/autonomous regions/municipalities, per capita disposable income in 2018, socioeconomic development level, and geographic region.
2009 - Multi-agent Systems in Modeling and Simulation of Fire Spread.pdf
Creators: name: Lima Ruas, Terry
name: Batista, André Filipe de Moraes
name: Marietto, Maria das Graças Bruno
Publisher: name: figshare
Year: 2021
Subjects: subject: 80110 Simulation and Modelling
subject: FOS: Computer and information sciences

description: This paper presents a conceptual study for the phenomenon of fire spread. The proposed study is based on simulations using the RoboCup Rescue environment. Using a socio-cognitive approach, it can be used in three dimensions: (i) assist in proposing new structures or alternatives to situations of collective panic, checking the viability of their existence and operation; (ii) obtain a better understanding of the reasons social, anthropological, psychological, etc. that subsidize and direct the type of collective behavior in crowd panic; (iii) assist in decision making aimed at minimizing the loss of life in a situation of spreadingfire. One of the challenges to be overcome in this research is the integration of the different theories andcomputational environments in order to open paths for future researches. Making possible a further studyon phenomenon of panic in crowds in danger situation.
title: ÐÑÐ°Ð¶Ð´Ð°Ð½ÑÐºÐ¾-Ð¿ÑÐ°Ð²Ð¾Ð²ÑÐµ ÑÑÐµÐ´ÑÑÐ²Ð° Ð·Ð°ÑÐ¸ÑÑ Ð¸Ð¼ÑÑÐµÑÑÐ²ÐµÐ½Ð½ÑÑ Ð¿ÑÐ°Ð² ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¸Ñ Ð¸ ÑÑÐ¸Ð´Ð¸ÑÐµÑÐºÐ¸Ñ Ð»Ð¸Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Civil law remedies to protect the property rights of individuals and legal entities
Creators: name: ÐÐ°Ð·ÑÑ, ÐÐ¼Ð¸ÑÑÐ¸Ð¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: Ð¸Ð¼ÑÑÐµÑÑÐ²Ð¾
Ð¸Ð¼ÑÑÐµÑÑÐ²ÐµÐ½Ð½ÑÐµ Ð¿ÑÐ°Ð²Ð°
Ð¿ÑÐ°Ð²Ð° ÑÐ¾Ð±ÑÑÐ²ÐµÐ½Ð½Ð¾ÑÑÐ¸
Ð²ÐµÑÐ½ÑÐµ Ð¿ÑÐ°Ð²Ð°
ÑÑÐ´ÐµÐ±Ð½ÑÐµ ÑÐµÑÐµÐ½Ð¸Ñ
Ð·Ð°ÑÐ¸ÑÐ° Ð¸Ð¼ÑÑÐµÑÑÐ²ÐµÐ½Ð½ÑÑ Ð¿ÑÐ°Ð² Ð³ÑÐ°Ð¶Ð´Ð°Ð½
property
property rights
court decisions
protection of citizens 'property rights

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ð° ÑÑÑÑ Ð²Ð¾Ð·Ð½Ð¸ÐºÐ½Ð¾Ð²ÐµÐ½Ð¸Ñ Ð¸ Ð·Ð°ÑÐ¸ÑÑ Ð¸Ð¼ÑÑÐµÑÑÐ²ÐµÐ½Ð½ÑÑ Ð¿ÑÐ°Ð² Ð² Ð Ð¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð¹ Ð¤ÐµÐ´ÐµÑÐ°ÑÐ¸Ð¸. ÐÑÑÐ»ÐµÐ´ÑÐµÑÑÑ, ÑÑÐ¾ Ð¿Ð¾ÑÑÐ¾ÑÐ½Ð½Ð¾Ðµ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ðµ Ð¾Ð±ÑÐµÑÑÐ²Ð° ÑÑÐµÐ±ÑÐµÑ Ð¾Ñ ÐºÐ°Ð¶Ð´Ð¾Ð³Ð¾ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²Ð° ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾Ð³Ð¾ Ð¼ÐµÑÐ°Ð½Ð¸Ð·Ð¼Ð° Ð·Ð°ÑÐ¸ÑÑ Ð¿ÑÐ°Ð² Ð¸ ÑÐ²Ð¾Ð±Ð¾Ð´ ÑÐµÐ»Ð¾Ð²ÐµÐºÐ°, Ð²ÐµÐ´Ñ Ð² ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð¼ Ð¼Ð¸ÑÐµ, ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸Ð·ÑÑÑÐµÐ¼ÑÑ Ð¿ÑÐ¸Ð·Ð½Ð°ÐºÐ°Ð¼Ð¸ Ð³Ð»Ð¾Ð±Ð°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¸ Ð²Ð·Ð°Ð¸Ð¼Ð½Ð¾Ð¹ Ð¸Ð½ÑÐµÐ³ÑÐ°ÑÐ¸Ð¸ Ð¾Ð±ÑÐµÑÑÐ²ÐµÐ½Ð½ÑÑ (Ð² ÑÐ¾Ð¼ ÑÐ¸ÑÐ»Ðµ â Ð¿ÑÐ°Ð²Ð¾Ð²ÑÑ) Ð¾ÑÐ½Ð¾ÑÐµÐ½Ð¸Ð¹, Ð²ÑÐµ Ð²Ð½Ð¸Ð¼Ð°Ð½Ð¸Ðµ Ð¼Ð¸ÑÐ¾Ð²Ð¾Ð³Ð¾ ÑÐ¾Ð¾Ð±ÑÐµÑÑÐ²Ð°, Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÑ Ð¸ Ð½Ð°ÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½ÑÑ Ð¿ÑÐ°Ð²Ð¸ÑÐµÐ»ÑÑÑÐ²ÐµÐ½Ð½ÑÑ Ð¸ Ð½ÐµÐ¿ÑÐ°Ð²Ð¸ÑÐµÐ»ÑÑÑÐ²ÐµÐ½Ð½ÑÑ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¹ ÑÐºÐ¾Ð½ÑÐµÐ½ÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¾ Ð½Ð° Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ðµ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ Ð¿ÑÐ°Ð² Ð¸ ÑÐ²Ð¾Ð±Ð¾Ð´ ÑÐµÐ»Ð¾Ð²ÐµÐºÐ° Ð¸ Ð³ÑÐ°Ð¶Ð´Ð°Ð½Ð¸Ð½Ð°.
description: This paper sets out the essence of the emergence and protection of property rights in the Russian Federation. It studies that the continuous development of society requires every state to create an effective mechanism for protecting human rights and freedoms, because in the modern world, characterized by signs of globalization and mutual integration of social (including legal) relations, all the attention of the world community, international and national government and non-governmental organizations focused on the problem of ensuring the rights and freedoms of man and citizen.
Shear Power Spectrum Reconstruction using Pseudo-Spectrum Method
Creators: name: Hikage, Chiaki
name: Takada, Masahiro
name: Hamana, Takashi
name: Spergel, David
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences

description: We develop a pseudo power spectrum technique for measuring the lensing power spectrum from weak lensing surveys in both the full sky and flat sky limits. The power spectrum approaches have a number of advantages over the traditional correlation function approach. We test the pseudo spectrum method by using numerical simulations with square-shape boundary that include masked regions with complex configuration due to bright stars and saturated spikes. Even when 25% of total area of the survey is masked, the method recovers the E-mode power spectrum at a sub-percent precision over a wide range of multipoles 100
description: 11 pages, 4 figures, accepted for publication in MNRAS
Pathophysiology and clinical manifestations of immune complex vasculitides
Creators: name: Sunderkötter, Cord
name: Golle, Linda
name: Pillebout, Evangéline
name: Michl, Christiane
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Immune complex (IC) vasculitides present inflammations of vessel walls associated with perivascular deposition of immunoglobulins (Igs), mostly ICs. They encompass systemic and skin-limited variants of IgA vasculitis (IgAV), cryoglobulinemic vasculitis (CV), rheumatoid, lupus, and hypocomplementemic vasculitides, serum sickness cutaneous IgM/IgG (non-IgA) vasculitis, and recurrent macular (hypergammaglobulinemic or exertion-induced) vasculitis. Serum sickness and CV fulfill the criteria of a type III hypersensitivity immune reaction as large lattices of the IC precipitate at vessel walls and activate polymorphonuclear neutrophils (PMNs). Immunoglobulin-A vasculitis differs with regard to the causes of perivascular deposition of ICs since here many IgA1 molecules are hypoglycosylated (Gd-IgA1), which appears to facilitate their perivascular deposition in skin and mesangium (via e.g. CD71). The reasons for increased generation of immunoglobulins or formation of IC and their perivascular deposition in either skin or systemic organs are different and not fully explored. A common denominator of OC vasculitides is the activation of PMNs near the vessel wall via Fcy or Fcα receptors. Acute episodes of IgAV additionally require PMNs to become preactivated by IgA1 or by IC already in circulation. This intravascular priming results in increased adherence and subsequently vessel-destructive NETosis when they encounter IgA deposited at the vessel walls. Binding of IgA1 to PMNs in blood stream is associated with increased serum levels of hypogalactosidated IgA1. The characteristic clinical picture of IgAV (and also of so-called IgG/IgM vasculitis) comprises palpable or retiform purpura with a clear predilection for lower legs, probably due to stasis-related reduction in blood velocity, while in other IC vasculitides, additional factors influence the sites of vasculitides. Our knowledge of distinct forms and different pathophysiological pathways of IC vasculitides may lead to in efficacious or targeted therapies. Antibodies to complement components or intestinal budesonide for IgAV are promising agents (the latter suppresses the pathophysiologically related IgA nephropathy by reducing the generation of mucosal IgA.
Effects of theophylline on ADCY5 activation : from cellular studies to improved therapeutic options for ADCY5-related dyskinesia patients
Creators: name: Tänzler, Dirk
name: Kipping, Marc
name: Lederer, Marcell
name: Günther, Wiebke F.
name: Arlt, Christian
name: Hüttelmaier, Stefan
name: Merkenschlager, Andreas
name: Sinz, Andrea
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: We show the effects of the three purine derivatives, caffeine, theophylline, and istradefylline, on cAMP production by adenylyl cyclase 5 (ADCY5)-overexpressing cell lines. A comparison of cAMP levels was performed for ADCY5 wild-type and R418W mutant cells. ADCY5-catalyzed cAMP production was reduced with all three purine derivatives, while the most pronounced effects on cAMP reduction were observed for ADCY5 R418W mutant cells. The gain-of-function ADCY5 R418W mutant is characterized by an increased catalytic activity resulting in elevated cAMP levels that cause kinetic disorders or dyskinesia in patients. Based on our findings in ADCY5 cells, a slow-release formulation of theophylline was administered to a preschool-aged patient with ADCY5-related dyskinesia. A striking improvement of symptoms was observed, outperforming the effects of caffeine that had previously been administered to the same patient. We suggest considering theophylline as an alternative therapeutic option to treat ADCY5-related dyskinesia in patients.
Free Probability based Capacity Calculation of Multiantenna Gaussian Fading Channels with Cochannel Interference
Creators: name: Chatzinotas, Symeon
name: Ottersten, Bjorn
Publisher: name: arXiv
Year: 2010
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: During the last decade, it has been well understood that communication over multiple antennas can increase linearly the multiplexing capacity gain and provide large spectral efficiency improvements. However, the majority of studies in this area were carried out ignoring cochannel interference. Only a small number of investigations have considered cochannel interference, but even therein simple channel models were employed, assuming identically distributed fading coefficients. In this paper, a generic model for a multi-antenna channel is presented incorporating four impairments, namely additive white Gaussian noise, flat fading, path loss and cochannel interference. Both point-to-point and multiple-access MIMO channels are considered, including the case of cooperating Base Station clusters. The asymptotic capacity limit of this channel is calculated based on an asymptotic free probability approach which exploits the additive and multiplicative free convolution in the R- and S-transform domain respectively, as well as properties of the eta and Stieltjes transform. Numerical results are utilized to verify the accuracy of the derived closed-form expressions and evaluate the effect of the cochannel interference.
description: 16 pages, 4 figures, 1 table
title: ÐÐ¾Ð½ÐµÑÐ½Ð¾-ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ½Ð¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð½Ð°Ð¿ÑÑÐ¶ÐµÐ½Ð½Ð¾-Ð´ÐµÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð³Ð¾ ÑÐ¾ÑÑÐ¾ÑÐ½Ð¸Ñ ÑÐ»Ð°Ð½ÑÐµÐ²Ð¾Ð³Ð¾ ÑÐ¾ÐµÐ´Ð¸Ð½ÐµÐ½Ð¸Ñ Ð²Ð°ÐºÑÑÐ¼Ð½Ð¾Ð³Ð¾ Ð±Ð°ÑÑÐµÑÐ° Ð½Ð¸Ð¶Ð½ÐµÐ³Ð¾ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿Ð¾ÑÑÐ° ÑÐµÑÐ¼Ð¾ÑÐ´ÐµÑÐ½Ð¾Ð³Ð¾ ÑÐµÐ°ÐºÑÐ¾ÑÐ° ÐÐ¢Ð­Ð
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Finite element modeling and study of the stress-strain state of the flange connection of the vacuum barrier of the lower diagnostic port of the ITER thermonuclear reactor
Creators: name: ÐÐ°Ð´ÐºÐ¾Ð²ÑÐºÐ¸Ð¹, ÐÐ»ÐµÐºÑÐ°Ð½Ð´Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: Ð¯Ð´ÐµÑÐ½ÑÐµ ÑÐµÐ°ÐºÑÐ¾ÑÑ
ÐÐ¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
ÐÐ¾Ð»ÑÐ¾Ð²ÑÐµ ÑÐ¾ÐµÐ´Ð¸Ð½ÐµÐ½Ð¸Ñ
Ð§Ð¸ÑÐ»ÐµÐ½Ð½ÑÐµ Ð¼ÐµÑÐ¾Ð´Ñ
Ð¤Ð»Ð°Ð½ÑÐµÐ²ÑÐµ ÑÐ¾ÐµÐ´Ð¸Ð½ÐµÐ½Ð¸Ñ
ÐºÐ¾Ð½ÐµÑÐ½Ð¾-ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð·
ÐºÐ¾Ð½ÑÐ°ÐºÑÑ
ÐºÐ¾Ð½ÐµÑÐ½Ð¾-ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ½Ð¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
finite element analysis
contacts
finite element simulation

description: Ð ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð½Ð¾ÑÐ¼Ð°ÑÐ¸Ð²Ð½ÑÑ Ð½Ð°Ð³ÑÑÐ·Ð¾Ðº, Ð²Ð¾Ð·Ð½Ð¸ÐºÐ°ÑÑÐ¸Ñ Ð¿ÑÐ¸ ÑÐºÑÐ¿Ð»ÑÐ°ÑÐ°ÑÐ¸Ð¸ ÐÐ¢ÐÐ . ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½ ÑÐ°ÑÑÐµÑ Ð¿Ð»Ð°ÑÑÐ¸Ð½Ñ Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð·Ð°ÐºÑÑÑÐ¸Ñ Ð¿ÑÐ¸ Ð´Ð°Ð½Ð½ÑÑ Ð½Ð°Ð³ÑÑÐ·ÐºÐ°Ñ. ÐÑÐµÐ½ÐµÐ½Ñ Ð½Ð°Ð¿ÑÑÐ¶ÐµÐ½Ð¸Ñ, Ð²Ð¾Ð·Ð½Ð¸ÐºÐ°ÑÑÐ¸Ðµ Ð² ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸ Ð¿ÑÐ¸ Ð½Ð¾ÑÐ¼Ð°ÑÐ¸Ð²Ð½ÑÑ Ð½Ð°Ð³ÑÑÐ·ÐºÐ°Ñ Ð¸ Ð¿ÑÐ¸Ð²ÐµÐ´ÐµÐ½Ñ ÑÐ¿Ð¾ÑÐ¾Ð±Ñ ÑÐ¼ÐµÐ½ÑÑÐµÐ½Ð¸Ñ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ Ð½Ð°Ð¿ÑÑÐ¶ÐµÐ½Ð¸Ð¹.
description: The study analyzes the standard loads arising during the operation of ITER. The calculation of the temporary closure plate for these loads has been performed. The stresses arising in the structure under standard loads are estimated and methods for reducing the resulting stresses are given.
title: ÐÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ PR-ÐºÐ°Ð¼Ð¿Ð°Ð½Ð¸Ð¸ Ñ ÑÐµÐ»ÑÑ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ ÑÐ°Ð±Ð¾ÑÑ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½ÑÑ ÑÑÑÐµÐ¶Ð´ÐµÐ½Ð¸Ð¹ ÐºÑÐ»ÑÑÑÑÑ (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ Ð¡ÐÐ± ÐÐÐ£Ð Â«ÐÐÐÐ¸ÐÂ»)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Organization of PR-campaign with the aim of improving the performance of public cultural institutions (on the example of SPb GBUK "ZPCandR")Â»)
Creators: name: ÐÐ°Ð»Ð°Ð±ÑÑÐµÐ², ÐÑÑÐµÑÐ»Ð°Ð²
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: PR-ÐºÐ°Ð¼Ð¿Ð°Ð½Ð¸Ñ
Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ðµ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸
Ð±ÑÐ´Ð¶ÐµÑÐ½Ð¾Ðµ ÑÑÑÐµÐ¶Ð´ÐµÐ½Ð¸Ðµ
PR campaign
efficiency improvement
budget institution

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÐ¿ÐµÑÐ¸ÑÐ¸ÐºÐ° Ð¸ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ PR-ÑÑÐµÐ´ÑÑÐ²Ð°, Ð¿ÑÐ¸Ð¼ÐµÐ½ÑÐµÐ¼ÑÐµ Ð² Ð½ÐµÐºÐ¾Ð¼Ð¼ÐµÑÑÐµÑÐºÐ¸Ñ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸ÑÑ. ÐÐ°Ð½Ð° Ð¾Ð±ÑÐ°Ñ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ° ÐÐÐ£Ð Ð¡ÐÐ ÐÐÐÐ¸Ð. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐµÐºÑÑÐµÐ¹ PR-Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð² ÑÐ¾ÑÐ¸Ð¾-ÐºÑÐ»ÑÑÑÑÐ½Ð¾Ð¹ ÑÑÐµÑÐµ. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½ ÑÐ¸ÑÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐÐÐÐ¸Ð. Ð¡Ð¾Ð·Ð´Ð°Ð½Ð¾ Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ PR ÐºÐ°Ð¼Ð¿Ð°Ð½Ð¸Ð¸ ÐÐµÐ»ÐµÐ½Ð¾Ð³Ð¾ÑÑÐºÐ¾Ð³Ð¾ Ð¿Ð°ÑÐºÐ°. ÐÐ¾Ð´Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ñ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ñ Ð¸ Ð¿Ð»Ð°Ð½Ñ ÐÐµÐ»ÐµÐ½Ð¾Ð³Ð¾ÑÑÐºÐ¾Ð³Ð¾ Ð¿Ð°ÑÐºÐ° ÐºÑÐ»ÑÑÑÑÑ Ð¸ Ð¾ÑÐ´ÑÑÐ° Ð½Ð° 2019-2020 Ð³Ð¾Ð´Ð°.
description: This paper discusses the specifics and basic PR tools used in non-profit organizations. The general characteristics of GBUK SPB ZPKiO are given. The analysis of current PR-activities in the socio-cultural sphere. A situational analysis of ZPKiO activity has been developed. Created planning a PR campaign of Zelenogorsk Park. The programs and plans of the Zelenogorsk recreation park for 2019-2020 have been prepared.
title: ÐÐ³ÑÐµÐ³Ð°ÑÐ¾Ñ Java Ð²Ð°ÐºÐ°Ð½ÑÐ¸Ð¹
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Java Vacancy Aggregator
Creators: name: ÐÐ°Ð·ÑÐ½, Ð¡ÑÐµÐ¿Ð°Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2023
Subjects: java
postgreSQL
maven
Ð²Ð°ÐºÐ°Ð½ÑÐ¸Ð¸
Ð¿Ð°ÑÑÐ¸Ð½Ð³
vacancies
parsing

description: Ð¢ÐµÐ¼Ð° Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ: âÐÐ³ÑÐµÐ³Ð°ÑÐ¾Ñ Java Ð²Ð°ÐºÐ°Ð½ÑÐ¸Ð¹â. Ð¦ÐµÐ»Ñ ÑÐ°Ð±Ð¾ÑÑ - ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð±ÑÐºÐµÐ½Ð´ ÐºÐ¾Ð´Ð° Ð½Ð° ÑÐ·ÑÐºÐµ Java Ð¿Ð¾ Ð¿Ð°ÑÑÐ¸Ð½Ð³Ñ Ð²Ð°ÐºÐ°Ð½ÑÐ¸Ð¹ Ñ ÑÐ°Ð¹ÑÐ¾Ð² Ð¸Ð½ÑÐµÑÐ½ÐµÑ-ÑÐµÐºÑÑÑÐ¼ÐµÐ½ÑÐ° Ð² Ð±Ð°Ð·Ñ Ð´Ð°Ð½Ð½ÑÑ Ð¸ Ð½Ð° ÑÐµÑÐ²ÐµÑ. ÐÐ°Ð´Ð°ÑÐ¸, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐµÑÐ°Ð»Ð¸ÑÑ Ð² ÑÐ¾Ð´Ðµ ÑÐ°Ð±Ð¾ÑÑ: 1. ÐÐ·ÑÑÐµÐ½Ð° Ð¾Ð±Ð»Ð°ÑÑÑ Ð¿Ð¾Ð¸ÑÐºÐ° Ð²Ð°ÐºÐ°Ð½ÑÐ¸Ð¹. 2. Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð°Ð½Ð°Ð»Ð¾Ð³Ð¸ÑÐ½ÑÐµ ÑÐµÑÐµÐ½Ð¸Ñ 3. ÐÐ±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð° ÑÐµÐ»ÐµÑÐ¾Ð¾Ð±ÑÐ°Ð·Ð½Ð¾ÑÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸ 4. Ð¡ÑÐ¾ÑÐ¼ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ñ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½ÑÐµ ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸Ñ Ðº ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐµ 5. ÐÐ¾ÑÑÑÐ¾ÐµÐ½Ð° ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð°Ñ Ð¼Ð¾Ð´ÐµÐ»Ñ 6. ÐÐ±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½ Ð²ÑÐ±Ð¾Ñ ÑÑÐµÐ´ÑÑÐ² ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ 7. Ð¡Ð¾ÑÑÐ°Ð²Ð»ÐµÐ½Ð¾ ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¾Ðµ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ðµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ð° Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÑÐ·ÑÐºÐ° Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Java, ÑÑÐµÐ´Ñ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸ Intellij Idea, Ð° ÑÐ°ÐºÐ¶Ðµ Ð¡Ð£ÐÐ PostgreSQL.
description: The topic of the final qualification work is "Java Vacancy Aggregator." The aim of the work is to develop the backend code in Java for parsing job vacancies from internet recruitment websites into a database and server. The tasks addressed during the work were as follows: 1. Studying the search of vacancies. 2. Examining similar solutions. 3. Justifying the feasibility of development. 4. Formulating functional requirements for development. 5. Building a functional model. 6. Justifying the choice of implementation tools. 7. Creating a technical description of the development. The development was carried out using the Java programming language, Intellij Idea development environment, and the PostgreSQL database management system.
Additional file 1: of Enhanced Thermoelectric Performance of c-Axis-Oriented Epitaxial Ba-Doped BiCuSeO Thin Films
Creators: name: Yuan, Dachao
name: Guo, Shuang
name: Hou, Shuaihang
name: Ma, Yuejin
name: Wang, Jianglong
name: Wang, Shufang
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Cancer
subject: Mental Health

description: Figure S1. The linear dependency of Hall voltage on the external magnetic field. Figure S2. The voltage difference (ΔV) vs. temperature difference (ΔT) plot for the Seebeck coefficient measured at 340 K of the Bi0.975Ba0.025CuSeO thin film. (DOCX 90 kb)
Energy bands, conductance and thermoelectric power for ballistic electrons in a nanowire with spin-orbit interaction
Creators: name: Gumbs, Godfrey
name: Balassis, Antonios
name: Huang, Danhong
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We calculated the effects of spin-orbit interaction (SOI) on the energy bands, ballistic conductance and the electron-diffusion thermoelectric power of a nanowire by varying the temperature, electron density and width of the wire. The potential barriers at the edges of the wire are assumed to be very high. A consequence of the boundary conditions used in this model is determined by the energy band structure, resulting in wider plateaus when the electron density is increased due to larger energy-level separation as the higher subbands are occupied by electrons. The nonlinear dependence of the transverse confinement on position with respect to the well center excludes the "pole-like feature" in the conductance which is obtained when a harmonic potential is employed for confinement. At low temperature, the electron diffusion thermoelectric power increases linearly with T but deviates from the linear behavior for large values of T.
description: Updated corrected version of the original submission
title: ÐÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ðµ Ð´Ð¾Ð¿ÑÑÑÐ¸Ð¼ÑÑ ÑÐµÐ¶Ð¸Ð¼Ð¾Ð² ÑÐ°Ð±Ð¾ÑÑ ÑÐ½ÐµÑÐ³Ð¾Ð±Ð»Ð¾ÐºÐ° â2 ÐÐÐ­Ð¡-2 Ð¸ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð² ÑÐ¸ÑÑÐµÐ¼Ñ Ð¿ÑÐ¾ÑÐ¸Ð²Ð¾Ð°Ð²Ð°ÑÐ¸Ð¹Ð½Ð¾Ð¹ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸ÐºÐ¸
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Determination of permissible operating modes of LNPP-2 power unit No. 2 and parameters of an emergency control system
Creators: name: ÐÐ¾Ð´Ð»ÐµÑÐ½ÑÐ¹, ÐÐ»ÐµÐ³
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: Ð­Ð»ÐµÐºÑÑÐ¾ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÑÐ¸ÑÑÐµÐ¼Ñ
Ð­Ð½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÑÐ¸ÑÑÐµÐ¼Ñ
ÐÐ­Ð¡ Ð¡ÐµÐ²ÐµÑÐ¾-ÐÐ°Ð¿Ð°Ð´Ð°
ÐÐÐ­Ð¡-2
Ð¿ÑÐ¾ÑÐ¸Ð²Ð¾Ð°Ð²Ð°ÑÐ¸Ð¹Ð½Ð°Ñ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸ÐºÐ°

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð±ÑÐ» Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ð¿ÑÐ¾Ð³Ð½Ð¾Ð· ÑÑÐ¾Ð²Ð½ÐµÐ¹ ÑÐ»ÐµÐºÑÑÐ¾Ð¿Ð¾ÑÑÐµÐ±Ð»ÐµÐ½Ð¸Ñ Ð¸ ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð½Ð°Ð³ÑÑÐ·Ð¾Ðº ÐÐ­Ð¡ Ð¡ÐµÐ²ÐµÑÐ¾-ÐÐ°Ð¿Ð°Ð´Ð° Ð½Ð° 2020 Ð³Ð¾Ð´. ÐÑÐ» Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐµÐ¶Ð¸Ð¼Ð¾Ð² ÑÐ°Ð±Ð¾ÑÑ ÐÐ­Ð¡ Ð¡ÐµÐ²ÐµÑÐ¾-ÐÐ°Ð¿Ð°Ð´Ð° Ð² Ð½Ð¾ÑÐ¼Ð°Ð»ÑÐ½Ð¾Ð¹, ÑÐµÐ¼Ð¾Ð½ÑÐ½ÑÑ Ð¸ Ð¿Ð¾ÑÐ»ÐµÐ°Ð²Ð°ÑÐ¸Ð¹Ð½ÑÑ ÑÑÐµÐ¼Ð°Ñ Ð¿ÑÐ¸ Ð²Ð²Ð¾Ð´Ðµ Ð² Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½ÑÑ ÑÐºÑÐ¿Ð»ÑÐ°ÑÐ°ÑÐ¸Ñ ÑÐ½ÐµÑÐ³Ð¾Ð±Ð»Ð¾ÐºÐ° â2 ÐÐÐ­Ð¡-2. ÐÑÐ»Ð¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ñ Ð´Ð¾Ð¿ÑÑÑÐ¸Ð¼ÑÐµ ÑÐµÐ¶Ð¸Ð¼Ñ ÑÐ°Ð±Ð¾ÑÑ ÐÐÐ­Ð¡-2. Ð¢Ð°ÐºÐ¶Ðµ Ð±ÑÐ» Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½ ÑÐ°ÑÑÐµÑ ÑÐ»ÐµÐºÑÑÐ¾Ð¼ÐµÑÐ°Ð½Ð¸ÑÐµÑÐºÐ¸Ñ Ð¿ÐµÑÐµÑÐ¾Ð´Ð½ÑÑ Ð¿ÑÐ¾ÑÐµÑÑÐ¾Ð² Ð² ÑÐ½ÐµÑÐ³Ð¾Ð¾Ð±ÑÐµÐ´Ð¸Ð½ÐµÐ½Ð¸Ð¸ Ð¸ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¾Ð¹ ÑÑÑÐ¾Ð¹ÑÐ¸Ð²Ð¾ÑÑÐ¸ Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ¾Ð² ÑÐ½ÐµÑÐ³Ð¾Ð±Ð»Ð¾ÐºÐ¾Ð² â1 Ð¸ â2 ÐÐÐ­Ð¡-2. ÐÐ° Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² Ð±ÑÐ»Ð° Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð° Ð¸ Ð²ÑÐ±ÑÐ°Ð½Ð° Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼Ð°Ñ Ð¿ÑÐ¾ÑÐ¸Ð²Ð¾Ð°Ð²Ð°ÑÐ¸Ð¹Ð½Ð°Ñ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸ÐºÐ° Ð´Ð»Ñ Ð½Ð°Ð´ÐµÐ¶Ð½Ð¾Ð³Ð¾ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÑÐ°Ð½ÑÐ¸Ð¸. ÐÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ Ð¸ ÑÑÑÐ°Ð²ÐºÐ¸ ÑÑÑÑÐ¾Ð¹ÑÑÐ² Ð¿ÑÐ¾ÑÐ¸Ð²Ð¾Ð°Ð²Ð°ÑÐ¸Ð¹Ð½Ð¾Ð¹ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸ÐºÐ¸.
description: In this paper, the forecast of the power consumption levels and electrical loads of the North-West IPS at the level of 2020 was made. An analysis of the operating modes of the North-West IPS was made in normal, repair and post-accident schemes when the LNPP-2 power unit No. 2 was put into commercial operation. Permitted modes of operation of LNPP-2 were investigated. Also, the calculation of electromechanical transients in the power connection was performed and the dynamic stability of the generator of the power unit No. 2 of Leningrad NPP-2 was analyzed. Based on the results obtained, the necessary emergency control system was justified and selected for reliable operation of the plant. The parameters and settings of the emergency control devices have been determined.
Beschluss der STIKO zur 12. Aktualisierung der COVID-19-Impfempfehlung
Creators: name: Ständige Impfkommission
Publisher: name: Robert Koch-Institut
Year: 2021
Subjects: subject: STIKO
subject: Impfempfehlung
subject: COVID-19
subject: Auffrischimpfung
subject: mRNA-Impfstoff
subject: 610 Medizin und Gesundheit

description: In der 12. Aktualisierung der COVID-19-Impfempfehlung empfiehlt die STIKO eine COVID-19-Auffrischimpfung mit einem mRNA-Impfstoff für Personen ≥ 70 Jahre und für bestimmte Indikationsgruppen sowie eine Optimierung der Grundimmunisierung mit einem mRNA-Impfstoff nach vorausgegangener Impfung mit der COVID-19 Vaccine Janssen.
Rotating BEC in an optical lattice in Uniformly frustrated Josephson Junction arrays regime: Vortex configuration formulation for ground state
Creators: name: Azizi, Y.
name: Valizadeh, A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We consider a rotating BEC in an optical lattices in a regime which can be mapped to the Joseohson junction arrays. In this regime, we formulate the ground state energy in terms of vortex configuration. This method give us the vortex lattice in the ground state in a natural way. We apply our result for an approximation scheme of the problem which we suppose that the coupling of the Josephson junctions are uniform. Application of method for ladder case presented and the results compared with Monte-Carlo method numerically.We discuss about restriction of method and suggest improvement for it.
description: 6 pages, 7 figures
STIKO-Empfehlung zur COVID-19-Auffrischimpfung mit einem mRNA-Impfstoff für Personen ≥ 70 Jahre und bestimmte Indikationsgruppen sowie Empfehlung zur Optimierung der Grundimmunisierung mit einem mRNA-Impfstoff nach vorausgegangener Impfung mit der COVID-19 Vaccine Janssen und die dazugehörige wissenschaftliche Begründung
Creators: name: Koch, Judith
name: Vygen-Bonnet, Sabine
name: Harder, Thomas
name: Ledig, Thomas
name: Mertens, Thomas
name: Michaelis, Kai
name: Schönfeld, Viktoria
name: Schmid-Küpke, Nora
name: Steffen, Annika
name: Wichmann, Ole
name: Wicker, Sabine
name: Überla, Klaus
Publisher: name: Robert Koch-Institut
Year: 2021
Subjects: subject: STIKO
subject: Impfempfehlung
subject: COVID-19
subject: Auffrischimpfung
subject: mRNA-Impfstoff
subject: 610 Medizin und Gesundheit

description: Die STIKO empfiehlt eine COVID-19-Auffrischimpfung mit einem mRNA-Impfstoff für Personen ≥ 70 Jahre und für bestimmte Indikationsgruppen. Die Auffrischimpfung soll frühestens 6 Monate nach der aus zwei Impfstoffdosen bestehenden Grundimmunisierung verabreicht werden. Es soll dafür ein mRNA-Impfstoff verwendet werden - unabhängig davon, welcher Impf¬stoff bei der vorher erfolgten homologen oder heterologen Immunisierung verwendet wurde. Bezüglich einer Optimierung der Grundimmunisierung nach vorausgegangener Impfung mit dem Vektor-basierten Janssen Impfstoff empfiehlt die STIKO Personen, die eine Grundimmunisierung mit einer Impfstoffdosis der COVID-19 Vaccine Janssen erhalten haben, eine weitere Impfung mit einem mRNA-Impfstoff zur Optimierung ihres Impfschutzes.
Post-stop fundamental frequency perturbation in production and perception of Mandarin stop voicing
Creators: name: Lo, Yu-Hsiang
Publisher: name: University of British Columbia
Year: 2022

description: This dissertation examines how Mandarin-dominant Mandarin-English bilinguals use post-stop fundamental frequency (F0) in the production and perception of the stop voicing contrast in Mandarin and English. Their use of post-stop F0 is then compared with that of native English speakers. Additionally, the influence of cognitive load on the use of post-stop F0 is investigated. Along with cross-linguistic differences in the use of post-stop F0, this work foregrounds variability within participants and explores the production-perception interface on an individual level. A corpus study and a set of parallel online production and perception experiments were devised. The results from the corpus study indicated that post-stop F0 following aspirated stops was lower than that following unaspirated stops in Mandarin. However, the data from the production experiment, in which the bilinguals read aloud words typifying the voicing contrast in stops, suggested the opposite pattern in both Mandarin and English. Furthermore, the post-stop F0 difference in English was larger as compared to Mandarin, indicating that more production weight was assigned to post-stop F0 in English than in Mandarin. The data from the perception experiment, which featured a forced-choice task, showed that the bilinguals used post-stop F0 as a cue in perceiving stops in both English and Mandarin, with higher post-stop F0 leading to more aspirated/voiceless responses, but they allocated more weight to post-stop F0 when the audio stimuli were presented as English words than as Mandarin words. When the bilinguals' post-stop F0 weights for English were compared with those of native English speakers, however, an asymmetry was revealed: even though both groups shared similar production weights, English listeners still had a higher perceptual weight than the bilinguals. With respect to cognitive load, which was induced by a concurrent visual search task, it seemed to introduce more variability to the perceptual weights, but only for English listeners. Overall, these results argue for a dual function of F0 in cueing phonological voicing in stops and tones across modalities in Mandarin. Furthermore, they suggest a dynamic nature of the post-stop F0 cue, which adapts to different language contexts, though this adaptability is constrained by the first language.
Generalized Kepler Problems I: Without Magnetic Charges
Creators: name: Meng, Guowu
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: For each simple euclidean Jordan algebra $V$ of rank $ρ$ and degree $δ$, we introduce a family of classical dynamic problems. These dynamical problems all share the characteristic features of the Kepler problem for planetary motions, such as existence of Laplace-Runge-Lenz vector and hidden symmetry. After suitable quantizations, a family of quantum dynamic problems, parametrized by the nontrivial Wallach parameter $ν$, is obtained. Here, $ν\in{\mathcal W}(V):=\{k {δ\over 2}\mid k=1, ..., (ρ-1)\}\cup((ρ-1){δ\over 2}, \infty)$ and was introduced by N. Wallach to parametrize the set of nontrivial scalar-type unitary lowest weight representations of the conformal group of $V$. For the quantum dynamic problem labelled by $ν$, the bound state spectra is $-{1/2\over (I+ν{ρ\over 2})^2}$, I=0, 1, ... and its Hilbert space of bound states gives a new realization for the afore-mentioned representation labelled by $ν$. A few results in the literature about these representations become more explicit and more refined. The Lagrangian for a classical Kepler-type dynamic problem introduced here is still of the simple form: ${1\over 2} ||\dot x||^2+{1\over r}$. Here, $\dot x$ is the velocity of a unit-mass particle moving on the space consisting of $V$'s semi-positive elements of a fixed rank, and $r$ is the inner product of $x$ with the identity element of $V$.
description: 30 pages
An algorithm for the principal component analysis of large data sets
Creators: name: Halko, Nathan
name: Martinsson, Per-Gunnar
name: Shkolnisky, Yoel
name: Tygert, Mark
Publisher: name: arXiv
Year: 2010
Subjects: subject: Computation (stat.CO)
subject: Numerical Analysis (math.NA)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Recently popularized randomized methods for principal component analysis (PCA) efficiently and reliably produce nearly optimal accuracy --- even on parallel processors --- unlike the classical (deterministic) alternatives. We adapt one of these randomized methods for use with data sets that are too large to be stored in random-access memory (RAM). (The traditional terminology is that our procedure works efficiently "out-of-core.") We illustrate the performance of the algorithm via several numerical examples. For example, we report on the PCA of a data set stored on disk that is so large that less than a hundredth of it can fit in our computer's RAM.
description: 17 pages, 3 figures (each with 2 or 3 subfigures), 2 tables (each with 2 subtables)
MPEC 2023-J82 : S/2020 S 7
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: S/2020 S 7

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
ADVISORY BODIES OF THE RUSSIAN FEDERAL BAR ASSOCIATION
Creators: name: Seleznev, A.
Publisher: name: Norwegian Journal of Development of the International Science
Year: 2020
Subjects: Federal Bar Association
Community Advisory Board
Scientific Advisory Board

description: The article describes the structure, legal basis, and operation of the advisory bodies in the Russian Federal Bar Association. Recommendations are given concerning the adoption of regulation on Community Advisory Board, and its structure.
Description of resources and recommendations for transition to adult health services for people with cerebral palsy
Creators: name: Ryan, Jennifer
Publisher: name: Zenodo
Year: 2023
Subjects: cerebral palsy
transition
health services

description: The tables contained in this document include information generated during a co-design process to develop resources to support transition from child to adult health services for young people with cerebral palsy. The full report is published in Frontiers in Rehabilitation Science https://www.frontiersin.org/articles/10.3389/fresc.2022.976580/full  Contents:  Table 1. Description of 13 ideas for resources generated by young people and parents. We summarised each idea in a single sentence and described how the idea responded to the transition needs of people with cerebral palsy identified by young people and parents. Table 2. Detailed description of 8 resources that were prioritised by young people with cerebral palsy and parents. All information was obtained from young people and parents. Text in italics indicates additional comments obtained from a health professional advisory group. Table 3. Additional recommendations to improve transition made by young people with cerebral palsy and parents. Recommendations are categorised under “health system”, “adult services”, “transition services”. Column entitled Design Stage indicates stage of the Design Thinking Approach process at which the recommendation was made.
The population of ULXs in the spiral galaxy NGC 2276
Creators: name: Wolter, Anna
name: Pizzolato, Fabio
name: Rota, Stefano
name: Mapelli, Michela
name: Ripamonti, Emanuele
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present results for X-ray point sources in the Sc galaxy NGC 2276, obtained by analyzing Chandra data. The galaxy is known to be very active in many wavelengths, possibly due to gravitational interaction with the central elliptical of the group, NGC 2300. However, previous XMM-Newton observations resulted in the detection of only one bright ULX and extended hot gas emission. We present here the X-ray population in NGC 2276 which comprises 17 sources. We found that 6 of them are new ULX sources in this spiral galaxy resolved for the first time by Chandra. We constructed the Luminosity Function that can be interpreted as mainly due of High Mass X-ray binaries, and estimate the Star Formation rate (SFR) to be SFR ~ 5-10 M_sun/yr.
description: 4 pages, 4 figures, Proceedings of the meeting 'Ultra-Luminous X-ray sources and Middle Weight Black Holes', ESAC, Madrid, Spain, May 2010