cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Chiral anomalies in the reduced model
Creators: name: Kikukawa, Yoshio
name: Suzuki, Hiroshi
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: On the basis of an observation due to Kiskis, Narayanan and Neuberger, we show that there is a remnant of chiral anomalies in the reduced model when a Dirac operator which obeys the Ginsparg-Wilson relation is employed for the fermion sector. We consider fermions belonging to the fundamental representation of the gauge group U(N) or SU(N). For vector-like theories, we determine a general form of the axial anomaly or the topological charge within a framework of a U(1) embedding. For chiral gauge theories with the gauge group U(N), a remnant of gauge anomaly emerges as an obstruction to a smooth fermion integration measure. The pure gauge action of gauge-field configurations which cause these non-trivial phenomena always diverges in the 't Hooft $N\to\infty$ limit when d>2.
description: 20 pages, uses JHEP.cls and amsfonts.sty, the final version to appear in JHEP
Transcending Locality, Creating Identity: Shinra Myojin, a Korean Deity in Japan
Creators: Kim, Su Jung
Publisher: name: Columbia University
Year: 2014
Subjects: Cults
Japanese--Religion
Buddhism
Area studies
Asians

description: This dissertation is about Shinra Myojin, a god of Silla that was worshipped in medieval Japanese Buddhism. It analyzes the various networks with which the deity was involved, namely, networks of Silla immigrants, Silla shrines and temples, and a variety of gods. Through examining the worship of Shinra Myojin from several different angles, each chapter has different, and yet related arguments. In the first chapter, I argue that the emergence of Shinra Myojin's cult can be fully understood when viewed within the context of the "East Asian Mediterranean" trade network, in which Silla merchants, immigrants, and Buddhist monks played a prominent role. In the second chapter, while focusing on a pivotal moment of the Shinra Myojin cult--a process of sedentarisation in which he changed from a sea deity into a mountain deity, I argue that Shinra Myojin was the central deity of Onjoji, as well as the entire Jimon tradition. The third chapter explains how the Japanese imaginaire of Silla was evolved, encoded and had effects in medieval Japan, and how Shinra Myojin functioned as a god of pestilence. Another pivotal point of Shinra Myojin's career was his mythological transformation from 'a god of Silla' to 'a god who conquered Silla.' In the last chapter, I analyze the visual representation of Shinra Myojin within this larger religious context, and argue that Shinra Myojin is best understood when we consider the deity in this network of other Silla-related deities, represented as an old man. The examination of Shinra Myojin's cult from an interdisciplinary angle serves as a gateway for exploring other understudied associations between medieval Japanese religiosity and those religious ideas and practices that were either continental in origin or were at least perceived to be so by medieval Japanese. My findings from interdisciplinary research contribute to elucidating those connections existing across the boundaries of religion, history, mythology, literature, and visual culture, all of which describes broader dynamics of East Asian religion as a whole.
Transcriptional control of somatosensory neuron diversification in Drosophila
Creators: Corty, Megan Marie
Publisher: name: Columbia University
Year: 2011
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Primary sensory neurons deliver information from the periphery to specific circuits in the central nervous system. It is vital that each sensory neuron detects the appropriate type of stimulus and conveys that information to appropriate regions of the sensory neuropil to target second-order neurons. Molecular programs that coordinate sensory morphology in the periphery with axon projection patterns centrally are poorly understood. I have used the multidendritic (md) sensory neurons of the Drosophila melanogaster peripheral nervous system to identify genetic and molecular programs that coordinate dendrite and axonal morphogenesis in individual sensory neurons. The homeodomain transcription factor Cut is expressed in neurons with complex dendrite morphologies that innervate the epidermis and ventral axon projections in the CNS, and is absent from putative proprioceptive neurons that have simpler dendrites and target to more dorsal CNS regions. In this thesis I demonstrate that, in defined subsets of sensory neurons, loss of Cut leads to dendritic transformation to a proprioceptive-type arbor that is accompanied by a dorsal shift in the termination of their axons in the CNS. Mechanistically, I show that Cut functions at least in part by repressing the expression of the POU domain transcription factors Pdm1 and Pdm2 (Pdm1/2), which are normally expressed only in proprioceptive neurons. Gain and loss of function studies further suggest instructive roles for Pdm1/2 in the development of proprioceptive dendritic arborization and axonal targeting. Together these results identify a transcriptional program that coordinately specifies proprioceptive dendrite morphology and sensory axon targeting to modality-specific domains of the CNS. Using a candidate based approached I have identified three molecular regulators of proprioceptive neuron dendrite morphology. In addition, gene profiling of sensory neurons forced to express Pdm2 has identified over 600 genes that show changes in expression when Pdm2 is misexpressed and that may mediate the effects of Pdm1/2 in directing proprioceptive dendrite and axon development. These profiling experiments pave the way for the identification of novel regulators of dendrite and axon morphogenesis that link transcriptional programs to specific morphologies with consequences for sensory circuit function.
title: SecureKeeper: Confidential ZooKeeper using Intel SGX
Creators: name: Brener, Stefan
name: Wulf, Colin
name: Goltzsche, David
name: Weichbrodt, Nico
name: Lorenz, Matthias
name: Fetzer, Christof
name: Pietzuch, Peter
name: Kapitza, Rüdiger
Publisher: name: Institut für Betriebssysteme und Rechnerverbund
Year: 2016
Subjects: subject: Cloud Computing
subject: Intel SGX
subject: Apache ZooKeeper
subject: 004

description: Cloud computing, while ubiquitous, still suffers from trust issues, especially for applications managing sensitive data. Third-party coordination services such as ZooKeeper and Consul are fundamental building blocks for cloud applications, but are exposed to potentially sensitive application data. Recently, hardware trust mechanisms such as Intel's Software Guard Extensions (SGX) offer trusted execution environments to shield application data from untrusted software, including the privileged Operating System (OS) and hypervisors. Such hardware support suggests new options for securing third-party coordination services. We describe SecureKeeper, an enhanced version of the ZooKeeper coordination service that uses SGX to preserve the confidentiality and basic integrity of ZooKeeper-managed data. SecureKeeper uses multiple small enclaves to ensure that (i) user-provided data in ZooKeeper is always kept encrypted while not residing inside an enclave, and (ii) essential processing steps that demand plaintext access can still be performed securely. SecureKeeper limits the required changes to the ZooKeeper code base and relies on Java's native code support for accessing enclaves. With an overhead of 11%, the performance of SecureKeeper with SGX is comparable to ZooKeeper with secure communication, while providing much stronger security guarantees with a minimal trusted code base of a few thousand lines of code.
Polyynes to Polycycles: The Synthesis of π-Rich Molecules via Domino Electrophilic Cyclisation of Polyynes
Creators: name: DILLON, ANNALIESE SELINA
Publisher: name: Monash University
Year: 2022
Subjects: subject: 30503 Organic Chemical Synthesis
subject: FOS: Chemical sciences
subject: Organic Chemistry

description: Enhancing synthetic access of π-rich materials through the development of an atom economical domino cyclisation reaction, poly-electrophilic cyclisations (PEC). A bottleneck exists within materials science whereby research and development are limited by available synthetic methods that can afford diverse libraries of π-rich polycyclic systems. The one step PEC reaction cascade developed has been shown to readily afford structurally diverse acenes and heteroacenes, from polyyne starting materials. This work has therefore provided materials scientists with bespoke synthetic methods to afford ’tuneable’ electronically and photonically active materials for applications within organic electronics and biomedical imaging.
Differential rotation of relativistic superfluid in neutron stars
Creators: name: Langlois, David
name: Sedrakian, David M.
name: Carter, Brandon
Publisher: name: arXiv
Year: 1997
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: It is shown how to set up a mathematically elegant and fully relativistic superfluid model that can provide a realistic approximation (neglecting small anisotropies due to crust solidity, magnetic fields, et cetera, but allowing for the regions with vortex pinning) of the global structure of a rotating neutron star, in terms of just two independently moving constituents, one of which represents the differentially rotating neutron superfluid, while the other part represents the combination of all the other ingredients, including the degenerate electrons, the superfluid protons in the core, and the ions in the crust, whose electromagnetic interactions will tend to keep them locked together in a state of approximately rigid rotation. Order of magnitude estimates are provided for relevant parameters such as the resistive drag coefficient and the maximum pinning force.
description: 35 pages, Latex, no figure, submitted to M.N.R.A.S
Additional file 1 of Robustness of textural analysis features in quantitative 99 mTc and 177Lu SPECT-CT phantom acquisitions
Creators: name: Gemmell, Alastair J.
name: Brown, Colin M.
name: Ray, Surajit
name: Small, Alexander
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Virology

description: Supplementary material 1
title: Süddeutsche Apotheker-Zeitung : Zeitschrift für Apotheker und Vertreter verwandter Berufszweige 35. Jg. 1895
Creators: name: :None
Publisher: name: Stähle & Friedl
Year: 1895
Subjects: subject: 615

description: Süddeutsche Apotheker-Zeitung: Zeitschrift für Apotheker und Vertreter verwandter Berufszweige, vol. 35, 1895
Information-Theoretic Limits of Control
Creators: name: Touchette, Hugo
name: Lloyd, Seth
Publisher: name: arXiv
Year: 1999
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Fundamental limits on the controllability of physical systems are discussed in the light of information theory. It is shown that the second law of thermodynamics, when generalized to include information, sets absolute limits to the minimum amount of dissipation required by open-loop control. In addition, an information-theoretic analysis of closed-loop control shows feedback control to be essentially a zero sum game: each bit of information gathered directly from a dynamical systems by a control device can serve to decrease the entropy of that system by at most one bit additional to the reduction of entropy attainable without such information (open-loop control). Consequences for the control of discrete binary systems and chaotic systems are discussed.
description: 4 pages, no figures
Transcriptional Regulation of Neuroectodermal Lineage Commitment in Embryonic Stem Cells
Creators: Huang, Yuan-Ping
Publisher: name: Columbia University
Year: 2014
Subjects: subject: Developmental biology
subject: Neurosciences
subject: FOS: Clinical medicine

description: Lineage commitment of pluripotent cells is a critical step in the development of multicellular organisms and a prerequisite for efficient differentiation of stem cells into terminal cell types. During successful neuroectodermal lineage commitment, extracellular signals terminate the pluripotency program, activate neural transcriptional program, and suppress alternative mesendodermal fate. Retinoic acid (RA) has been identified as a potent inducer of neural differentiation in embryonic stem cells (ESCs), yet the transcriptional program initiated by RA is poorly understood. Expression profiling of differentiating ESCs revealed delayed response of the pluripotency marker Oct4 and neural marker Sox1 following RA treatment, suggesting that RA regulates the pluripotency program and neural transcriptional program indirectly through induction of additional transcription factors.
               In this study, I identified a zinc finger factor Zfp703 as a downstream effector of RA-mediated neuroectodermal lineage commitment. Zfp703 expression in ESCs resulted in Oct4 repression, Sox1 induction, and neural differentiation. Moreover, Zfp703 strongly suppresses mesendodermal fate by repressing genes such as Brachyury, Eomes, and Mixl1 even under conditions favoring mesendoderm specification. Zfp703 binds to and represses Lef1 promoter, raising the possibility that it might modulate Wnt signaling via regulating Lef1. Finally, Zfp703 is not required for RA-mediated Oct4 repression and Sox1 induction. However, it is necessary for efficient Brachyury repression by RA. Based on these data, I propose that Zfp703 is involved in the transcription regulation during neural progenitor specification. Through downregulating of both mesendodernal fate and pluripotency, Zfp703 de-represses neural transcriptional program and indirectly promotes the default neuroectodermal lineage commitment.
Transcription factor activating protein 4 is synthetic lethal and a master regulator of MYCN amplified neuroblastoma
Creators: Zhang, Shuobo
Publisher: name: Columbia University
Year: 2015
Subjects: Neuroblastoma--Genetic aspects
Transcription factors
Nervous system--Cancer
Neuroblastoma
Cytology

description: Despite the identification of MYCN amplification as an adverse prognostic marker in neuroblastoma, no drugs that target MYCN have yet been developed. Here, by combining a whole genome shRNA library screen and Master Regulator Inference Algorithm (MARINa) analysis, we identified Transcription Factor Activating Protein 4 (TFAP4) as a novel synthetic lethal interactor with MYCN amplification in neuroblastoma. Silencing TFAP4 selectively inhibits MYCN amplified neuroblastoma growth both in vitro and in xenograft mice models. TFAP4 expression is inversely correlated with patient survival in MYCN-high neuroblastoma. Mechanistically, silencing TFAP4 induces neuroblastoma differentiation, as seen by increased neurite outgrowth, and up-regulation of neuronal markers. TFAP4 regulates a downstream signature similar to the signature of the oncogene anaplastic lymphoma kinase (ALK). Taken together, our results validate TFAP4 as an important master regulator in MYCN amplified neuroblastoma and a novel synthetic interactor with MYCN amplification. Thus, TFAP4 may be a novel drug target for neuroblastoma treatment.
Managing for the multiple uses and values of Moreton Bay and its catchments
Creators: name: Ross, Helen
name: Rissik, David
name: Jones, Natalie
name: Witt, Katherine
name: Pinner, Breanna
name: Shaw, Sylvie
Publisher: name: figshare
Year: 2019
Subjects: subject: 50205 Environmental Management
subject: FOS: Earth and related environmental sciences

description: Paper contribution to the Moreton Bay (Quandamooka) & Catchment eBook available on www.moretonbayfoundation.org.
title: Süddeutsche Apotheker-Zeitung : Zeitschrift für Apotheker und Vertreter verwandter Berufszweige, 36. Jg. 1896
Creators: name: :None
Publisher: name: Stähle & Friedl
Year: 1896
Subjects: subject: 615

description: Süddeutsche Apotheker-Zeitung: Zeitschrift für Apotheker und Vertreter verwandter Berufszweige, vol. 36, 1896
A small guide to variations in teleparallel gauge theories of gravity and the Kaniel-Itin model
Creators: name: Muench, Uwe
name: Gronwald, Frank
name: Hehl, Friedrich W.
Publisher: name: arXiv
Year: 1998
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Recently Kaniel & Itin proposed a gravitational model with the wave type equation [\square+λ(x)]\vartheta^α=0 as vacuum field equation, where \vartheta^αdenotes the coframe of spacetime. They found that the viable Yilmaz-Rosen metric is an exact solution of the tracefree part of their field equation. This model belongs to the teleparallelism class of gravitational gauge theories. Of decisive importance for the evaluation of the Kaniel-Itin model is the question whether the variation of the coframe commutes with the Hodge star. We find a master formula for this commutator and rectify some corresponding mistakes in the literature. Then we turn to a detailed discussion of the Kaniel-Itin model.
description: 33 pages LATEX, one postscript figure included
Additional file 2 of Robustness of textural analysis features in quantitative 99 mTc and 177Lu SPECT-CT phantom acquisitions
Creators: name: Gemmell, Alastair J.
name: Brown, Colin M.
name: Ray, Surajit
name: Small, Alexander
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Virology

description: Supplementary material 2
Nicolai mapping vs. exact chiral symmetry on the lattice
Creators: name: Kikukawa, Yoshio
name: Nakayama, Yoichi
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Two-dimensional N=2 Wess-Zumino model is constructed on the lattice through Nicolai mapping with Ginsparg-Wilson fermion. The Nicolai mapping requires a certain would-be surface term in the bosonic action which ensures the vacuum energy cancellation even on the lattice, but inevitably breaks chiral symmetry. With the Ginsparg-Wilson fermion, the holomorphic structure of the would-be surface term is maintained, leaving a discrete subgroup of the exact chiral symmetry intact for a monomial scalar potential. By this feature both boson and fermion can be kept massless on the lattice without any fine-tuning.
description: 15 pages, no figure, LaTeX2e; added references
A Laguerre Polynomial Orthogonality and the Hydrogen Atom
Creators: name: Dunkl, Charles F.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Mathematical Physics (math-ph)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 81Q05, 33C25

description: The radial part of the wave function of an electron in a Coulomb potential is the product of a Laguerre polynomial and an exponential with the variable scaled by a factor depending on the degree. This note presents an elementary proof of the orthogonality of wave functions with differing energy levels. It is also shown that this is the only other natural orthogonality for Laguerre polynomials. By expanding in terms of the usual Laguerre polynomial basis an analogous strange orthogonality is obtained for Meixner polynomials.
description: 13 pages, LaTeX, new section on Meixner polynomials
Transfer and Generalization of Learned Manipulation between Unimanual and Bimanual Tasks
Creators: Lee-Miller, Trevor
Publisher: name: Columbia University
Year: 2020
Subjects: subject: Kinesiology
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Motor ability
subject: Torque

description: Successful grasping and dexterous object manipulation relies on the ability to form internal representations of object properties that can be used to control digit kinetics and kinematics. Sensory cues and sensorimotor experience enable the updating of these internal representations. Aside from the weight of the object, the center of mass of the object results in object torque that needs to be represented and compensated for. In order to counter object torque, digit forces and centers of pressure are modulated to generate a compensatory moment to prevent object roll. Generalization studies can be used to examine whether this learning is represented on a low effector-specific level or a high task-specific level. Previous studies have shown that the internal representation of object torque does not generalize after object rotation or contralateral hand switch suggesting an effector level of representation. However, it has been shown that switching from two to three digits and vice versa does lead to full generalization suggesting a high level representation in certain circumstances. Thus, an understanding of whether learned manipulation would generalize when adding or removing the number of degrees of freedom and effectors would provide more information on these levels of representation. We asked 30 participants to lift a visual symmetrical object with an asymmetrical center of mass. Participants lifted the object 10 times in one grasp type (right hand unimanual, bimanual, or left hand unimanual). Following that, they switched to another grasp type and lifted the object another 10 times. Through various different orders of these transfer blocks, we examined their ability to generalize between unimanual and bimanual grasping by comparing the pre- and post-transfer trials. Our results show the partial generalization of learned manipulation when switching between unimanual and bimanual grasps. This is shown from the reduction in peak roll after transfer compared to novel trials and the generation of compensatory moments in the appropriate direction (but insufficient magnitude) after transfer. Moreover, after transfer to the right hand unimanual and bimanual grasps, moment generation was driven by digit center of pressure modulation while transfer for left hand unimanual grasps was driven by load force modulation. In addition, we also show failed generalization after contralateral hand switch as evidenced by large post-transfer rolls and minimal moments. We suggest that learned manipulation of object torque is a high level of representation but that this representation can only be accessed by either digit kinematics or kinetics, depending on the hand used.
Lattice Predictions for Hybrids and Glueballs
Creators: name: McNeile, Craig
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: I review the results from lattice gauge theory for the properties of the light 1-+ exotic state and 0++ glueball.
description: Talk presented at the European Workshop on the QCD Structure of the Nucleon held at Ferrara on April 3-6,2002
Maximising the Impact of your Research Data
Creators: name: Monash University Research Repository
Publisher: name: Monash University
Year: 2020
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications
subject: 150502 Marketing Communications
subject: FOS: Economics and business

description: Altmetrics or ‘alternative metrics’ are measures of attention and conversation surrounding research outputs in social media, news outlets and open web sources. They allow researchers to better understand how their work is being discussed, shared, read, and reused by other scholars and the public. Along with traditional metrics, this data is vital to securing grant funding, supporting promotion and tenure, and managing your scholarly reputation.
Every item and collection record in Bridges can display an Altmetric donut that will allow you to see who is talking about your research, where they are, and what they’re saying.
This document, created by Monash University Library and based on information published by Altmetric, provides a quick explanation of altmetrics as a tool for researchers and as a feature of Bridges, and provides tips for researchers wanting to increase engagement with their research.

[In early 2020, the repository was renamed from monash.figshare to Bridges. Version 1 of this record links to the previous monash.figshare guide.]
title: AsyncShock: Exploiting Synchronisation Bugs in Intel SGX Enclaves
Creators: name: Weichbrodt, Nico
name: Kurmus, Anil
name: Pietzuch, Peter
name: Kapitza, Rüdiger
Publisher: name: Institut für Betriebssysteme und Rechner
Year: 2016
Subjects: subject: Intel Software Guard Extensions
subject: Intel SGX
subject: Synchronisation Bugs
subject: Trusted Execution
subject: 004

description: Intel's Software Guard Extensions (SGX) provide a new hardware-based trusted execution environment on Intel CPUs using secure enclaves that are resilient to accesses by privileged code and physical attackers. Originally designed for securing small services, SGX bears promise to protect complex, possibly cloud-hosted, legacy applications. In this paper, we show that previously considered harmless synchronisation bugs can turn into severe security vulnerabilities when using SGX. By exploiting use-after-free and time-of-check-to-time-of-use (TOCTTOU) bugs in enclave code, an attacker can hijack its control flow or bypass access control.
We present AsyncShock, a tool for exploiting synchronisation bugs of multithreaded code running under SGX. AsyncShock achieves this by only manipulating the scheduling of threads that are used to execute enclave code. It allows an attacker to interrupt threads by forcing segmentation faults on enclave pages. Our evaluation using two types of Intel Skylake CPUs shows that AsyncShock can reliably exploit use-after-free and TOCTTOU bugs.
Transcriptional control of tissue-resident memory T cell generation
Creators: Cvetkovski, Filip
Publisher: name: Columbia University
Year: 2019
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: T cells
subject: Genetic transcription

description: Tissue-resident memory T cells (TRM) are a non-circulating subset of memory that are maintained at sites of pathogen entry and mediate optimal protection against reinfection. Lung TRM can be generated in response to respiratory infection or vaccination, however, the molecular pathways involved in CD4+TRM establishment have not been defined. Here, we performed transcriptional profiling of influenza-specific lung CD4+TRM following influenza infection to identify pathways implicated in CD4+TRM generation and homeostasis. Lung CD4+TRM displayed a unique transcriptional profile distinct from spleen memory, including up-regulation of a gene network induced by the transcription factor IRF4, a known regulator of effector T cell differentiation. In addition, the gene expression profile of lung CD4+TRM was enriched in gene sets previously described in tissue-resident regulatory T cells. Up-regulation of immunomodulatory molecules such as CTLA-4, PD-1, and ICOS, suggested a potential regulatory role for CD4+TRM in tissues. Using loss-of-function genetic experiments in mice, we demonstrate that IRF4 is required for the generation of lung-localized pathogen-specific effector CD4+T cells during acute influenza infection. Influenza-specific IRF4−/− T cells failed to fully express CD44, and maintained high levels of CD62L compared to wild type, suggesting a defect in complete differentiation into lung-tropic effector T cells. This finding identifies IRF4 as an important regulator of CD4+TRM generation in response to respiratory infection. Furthermore, comparing whole transcriptome profiling of mouse and human lung memory T cell subsets, we define a lung CD4+TRM gene signature common to mice and humans. IRF4 protein was specifically up-regulated in lung CD4+TRM but not in circulating memory subsets, in both humans and mice previously infected with influenza. This result suggest that high expression of IRF4 contributes to a cross-species conserved molecular pathway of long term maintenance of CD4+TRM in the lung. Overall, our findings confirm lung CD4+TRM as a unique memory T cell subset regulated by tissue-specific transcription factors. These results have important implications in focusing future studies of tissue resident memory T cells to factors with translational potential. Importantly, by determining the lung CD4+TRM gene signature common to mice and humans, we motivate future genetic studies that could lead to the complete identification of the mechanisms of TRM maintenance in humans.
GN5-1 Software Licence Selection and Management in GÉANT
Creators: name: Marović, Branko
name: Rząca, Magdalena
Publisher: name: GÉANT
Year: 2024
Subjects: GÉANT
GÉANT project
GN5-1
WP9
Operations Support
Software Governance
Software Support
Open Source Software
OSS
Licence Management
Licence Selection
Licence Compliance

description: This document provides a detailed guide to software licence selection, declaration, compliance and management in GÉANT. Intended for software development teams, it contains both essential information and practical step-by-step instructions. It is divided into two main parts: Essential Aspects and Elements of Software Licensing, and Complying with a Selected Licence.
Error analysis of an accelerated interpolative decomposition for 3D Laplace problems
Creators: name: Xing, Xin
name: Chow, Edmond
Publisher: name: arXiv
Year: 2018
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65G99

description: In constructing the $\mathcal{H}^2$ representation of dense matrices defined by the Laplace kernel, the interpolative decomposition of certain off-diagonal submatrices that dominates the computation can be dramatically accelerated using the concept of a proxy surface. We refer to the computation of such interpolative decompositions as the proxy surface method. We present an error bound for the proxy surface method in the 3D case and thus provide theoretical guidance for the discretization of the proxy surface in the method.
On the "circular vacuum noise" in electron storage rings
Creators: name: Rosu, H. C.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We discuss the proposal of Bell and Leinaas (BL) to measure the circular Unruh effect in storage rings. The ideal concept `circular Unruh effect' has a more realistic correspondent such as `circular vacuum noise' used by Shin Takagi [Prog. Theor. Phys. Suppl. 88, 1 (1986)] The BL resonance behavior does not fit to the SPEAR first order betatron resonance at 3.605 GeV, but of course, the real experimental situation is much more complicated, corresponding, as a matter of fact, to an even more general term that one may call `synchrotron noise'. In the final section we focus on radiometric aspects of storage ring physics, such as the problem of establishing better quantum field radiometric standards at high energies. The Unruh-like effect could be a useful guide for that purpose
description: 11pp, paper written in January 1992, some update of references
Collaboration Versus Cheating
Creators: name: Mason, Tony
name: Gavrilovska, Ada
name: Joyner, David A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: We outline how we detected programming plagiarism in an introductory online course for a master's of science in computer science program, how we achieved a statistically significant reduction in programming plagiarism by combining a clear explanation of university and class policy on academic honesty reinforced with a short but formal assessment, and how we evaluated plagiarism rates before SIGand after implementing our policy and assessment.
description: 7 pages, 1 figure, 5 tables, SIGCSE 2019
Transformed Within, Transformed Without: The Enactment of Religious Conversion in Medieval and Early Modern European Saint Plays
Creators: Kuntz, Emily Ciavarella
Publisher: name: Columbia University
Year: 2020
Subjects: Theater
History
Religion
Conversion
Mysteries and miracle-plays
Christianity

description: My dissertation investigates the ways in which both medieval and early modern saint plays depict and incite religious conversion through self-aware theatrical techniques. In each of my chapters, I examine one or two popular saint plays from a given period and area (medieval England, medieval France, early modern Spain, and early modern England) and show how each play invites the audience to undergo a spiritual shift parallel to that of the saint protagonist. These playmakers harnessed the affective power and technology of theatrical performance to invite the audience to engage with performed religious conversion in a controlled, celebratory environment and to encourage them to convert toward a more deeply felt Christianity. The plays reconfigured the audience’s sensory and intellectual understanding of Christian theology in order for the audience to recognize spiritual truth within an inherently communal, participatory, and performative space. The plays I examine depend on the audience’s familiarity with theatrical culture and practice in order to distinguish between sincere and insincere religious performance. By making the process of conversion a theatrical performance onstage, these plays could advocate for the theatrical medium as a genuine and effective catalyst for spiritual renewal. In addition to joining the conversation on the nature and goals of early European theatre, my dissertation also argues for the continued intersection between performance studies and conversion studies, demonstrating the ways in which theatrical performance elucidates the ways in which communities can instigate and collectively feel conversion.
Transformative Learning in Sculpture Class: Exploring New Identities as Artists, Approaches to Artmaking, and Understanding of Art
Creators: Koo, Sohee
Publisher: name: Columbia University
Year: 2019
Subjects: Art--Study and teaching
Adult education
Transformative learning
Identity (Psychology)

description: Transformative Learning seeks to encourage learners to critically reflect on their assumptions and preconceptions, thereby transforming their existing frameworks and perspectives. This qualitative study investigates what Transformative Learning looks like in a diverse group of adult learners at a graduate school of education who attended sculpture classes intentionally designed to enable such change. When Transformative Learning is part of the teacher’s intention, how, if at all, does learning through artmaking in mixed media sculpture classes transform these adults with regard to their understanding of their identities as artists and learners (“Who am I?”), their approaches to artmaking (“How do I make art?”), and their understanding of art (“What is art?”)? Furthermore, the study seeks to understand what aspects of their class experiences contributed to these transformations. The study examines the studio creations and artmaking processes of five adults from diverse backgrounds and experiences and analyzes what they reported about their artmaking experiences. Data gathered from semi-structured interviews, retrospective surveys, and class artifacts are organized and analyzed based on three stages of the Transformative Learning cycle—Stability, Reflection, and Transformation. The five participants’ three stages are then discussed according to the participants’ perceptions of their identities as artists, their understanding of art, and their approaches to artmaking, based on the research questions. The findings of the study suggest that the participants experienced heightened levels of Transformative Learning in individualized ways. Data indicate that specific class activities—a gallery trip, in-class artmaking sessions with material and time constraints, and an artist statement exercise—contributed to participants’ transformations over the course of the semester. Once the semester ended, some participants took further actions based on their changed perspectives of artist identities, understanding of art, and approaches to artmaking, which indicates that dramatic shifts and multiple perspectives can be achieved in an art class designed to teach for Transformative Learning.
Transformations of the Beautiful: Beauty and Instability in Eighteenth- and Early Nineteenth-Century German Literature
Creators: Salvo, Arthur Kemble
Publisher: name: Columbia University
Year: 2015
Subjects: Feminine beauty (Aesthetics) in literature
Aesthetics in literature
German literature
Aesthetics

description: Transformations of the Beautiful reexamines a problem that emerges during the mid-eighteenth century: the devaluation of the aesthetic category of the beautiful. In opposition to accounts that identify this problem with the rediscovery of the sublime, this dissertation emphasizes the crucial yet underexamined role that historicization played in the destabilization of beauty’s normative status in German aesthetic discourse. Additionally, I demonstrate that literary discourse became a key mode through which the beautiful’s problematic status was negotiated. Assembling literary texts from 1759-1817 that thematize beautiful objects or phenomena in terms of their historicity or instability, and transform them, I argue that these moments constitute discrete instances in which literature responds to the precarious position of beauty in modernity. With recourse to texts by Winckelmann, Schiller, Jean Paul, Ernst August Friedrich Klingemann and Eichendorff, I focus on the specific literary techniques employed by different genres—description, elegy, and narrative fiction—and how they reconfigure the relationship between the modern subject and the beautiful. In so doing I demonstrate how literary texts intervene in aesthetic discourse to reevaluate and generate alternative conceptions of the beautiful.
Transforming Growth Factor Beta Signaling in motor neurons in a mouse model of Amyotrophic Lateral Sclerosis
Creators: Braine, Catherine Elizabeth
Publisher: name: Columbia University
Year: 2022
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Amyotrophic lateral sclerosis
subject: Motor neurons--Diseases
subject: Nervous system--Diseases
subject: Diseases--Animal models

description: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease caused by the death of motor neurons in the spinal cord and brain. ALS is a genetically complex disease; diverse mutations cause motor neuron death by disrupting various interrelated pathways. To date, no therapy targeting a single factor can rescue motor neuron loss, nor is it known how or why sub-populations of motor neurons are particularly vulnerable in disease. Many studies have pointed to the Transforming Growth Factor Beta (TGF-𝝱) signaling superfamily as a modifier of disease in human patients and in animal models. Here, we have used the SOD1G93A model of ALS to investigate if and how TGF-𝝱 signaling in motor neurons changes pathology in these animals. In the first part of this study we characterize canonical TGF-𝝱 activation in motor neurons in SOD1G93A animals compared to controls. We have found that a vulnerable motor neuron subpopulation upregulates TGF-𝝱RII, a receptor necessary and unique to the classical arm of the TGF-𝝱 signaling family, in a disease dependent manner. Despite the upregulation of TGF-𝝱RII in these cells, there is not a corresponding activation of downstream canonical TGF-𝝱 effectors in diseased motor neurons. Through in vivo genetic manipulation we found that TGF-𝝱RII is dispensable in motor neurons, but that ablation of TGF-𝝱RI, a key receptor in multiple arms of the TGF-𝝱 superfamily, decreases motor neuron survival in SOD1G93A animals. To further understand how this manipulation changes TGF-𝝱 activation in motor neurons, we performed iterative indirect immunoflourescence imaging. We have identified that knocking out TGF-𝝱RI from motor neurons disrupts downstream canonical TGF-𝝱 activation in these cells. To identify how TGF-𝝱 signaling changes gene expression in these cells we have used Visium, a spatial RNAseq method, on lumbar spinal cords from these animals We have identified and are currently investigating potential downstream targets of TGF-𝝱 signaling in motor neurons in SOD1G93A animals. These data suggest that motor neurons rely on TGF-𝝱 signaling for survival in disease and that TGF-𝝱 signaling is important to the biology of a known vulnerable population of motor neurons.
Charting a course by the stars; a review of progress towards a comprehensive management plan for Moreton Bay 20 years on
Creators: name: Davidson, Andrew
name: Choy, Darryl Low
Publisher: name: figshare
Year: 2019
Subjects: Environmental Science

description: Paper contribution to the Moreton Bay (Quandamooka) & Catchment eBook available on www.moretonbayfoundation.org
Understanding the epidemiology and global burden of rare kidney disease: a scoping review protocol
Creators: name: Agarwal, Neeru
name: Smyth, Brendan
name: Moorthy, Monica
name: Malik, Charu
name: Pais, Priya
name: Vivekanand Jha
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Medicine and Health Sciences
subject: epidemiology
subject: incidence
subject: orphan diseases
subject: prevalence
subject: rare kidney diseases

description: Objective: The objective of this scoping review is to understand the epidemiology of rare kidney diseases (RKDs).

Introduction: There are over 400 RKDs which encompass various genetic and acquired kidney disorders, affecting both children and adults. However, estimating the prevalence and incidence of RKDs is complicated due to a diverse range of data sources, differing case ascertainment methods, and the absence of a standardized coding system. Networks, registries, and cohort databases have been created to help counter this, however, data gaps exist in certain regions of the world.

Inclusion criteria: RKDs will be defined by the Orphanet classification system. Original papers that describe epidemiological indicators of RKDs (e.g., prevalence, incidence, and case reports) with kidney manifestations/complications will be included in this scoping review.

Methods: Using a complex search string that combine keyword search terms for all individual RKDs, and epidemiological specific keywords such incidence, prevalence, case study and epidemiology, with focus on kidney disease, will be searched. Studies published in the English language, and over the past 10 years (2013-2023) will be compiled and uploaded into Covidence, a systematic review software. Titles and abstracts will be independently screened by at least two reviewers. The full text of selected studies will be assessed against the eligibility criteria and data will be extracted using a data extraction tool by at least two reviewers. Disagreements between the reviewers at any stage will be resolved through discussion or consultation with another reviewer. Descriptive statistics will be used to describe the data, including a world map to describe the epidemiological research currently being undertaken.
Additional file 7 of Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium handling
Creators: name: Wu, Jinchun
name: Liu, Tao
name: Shi, Shaobo
name: Fan, Zhixing
name: Hiram, Roddy
name: Xiong, Feng
name: Cui, Bo
name: Su, Xiaoling
name: Chang, Rong
name: Zhang, Wei
name: Yan, Min
name: Tang, Yanhong
name: Huang, He
name: Wu, Gang
name: Huang, Congxin
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 7: Table S2. Echocardiographic parameters of the four groups of rats.
Transforming Long Island City: Examining the Impacts of Rezoning
Creators: Ellmore, Sarah
Publisher: name: Columbia University
Year: 2015
Subjects: City planning--Social aspects
Zoning--Economic aspects
Zoning law--U.S. states
City planning--Economic aspects
Zoning
City planning
Regional planning

description: In response to non-contextual development occurring in the early 20th Century, became the first city in the United States to develop zoning regulations in 1916 to control land use and bulk throughout the city. These regulations, however, are not finite as the city is continuously evolving. Since the comprehensive overhaul of the zoning text in 1961 the City has taken a more piecemeal approach and began to target specific areas for rezoning. These piecemeal rezonings have occurred over much of New York City beginning in 2001 and minimal research has been done to determine the ability of the rezonings to meet their projected goals or to determine the impacts caused on their respective communities. The aim of this thesis is to understand the changes that have occurred as a result of the rezoning of the Long Island City Queens by comparing the changes that have occurred in specified socio-demographic categories within the boundaries of the rezoning to those outside the rezoning in Long Island City from 1990 to 2013 and to examine the changes in local economy from 2000 to 2012. The thesis will use both quantitative and qualitative methods in order to gain an understanding of the changes that have resulted from the rezoning.
The battle between NoSQL Databases and RDBMS
Creators: name: Mukherjee, Sourav
Publisher: name: figshare
Year: 2019
Subjects: subject: 80604 Database Management
subject: FOS: Computer and information sciences
subject: Computer Software
subject: Computer Engineering
subject: 80303 Computer System Security

description: NoSQL is a free and open-source, scattered, extensive column store database management system intended to handle large amounts of data across many product servers, providing high obtainability and accessibility with no single point of failure. It is the easiest truly big-data database that can scale and replicate data globally in a master-less configuration. A NoSQL database delivers a mechanism for storage and recovery of data that is demonstrated in means other than the tabular relations used in relational databases. NoSQL databases usually understood by engineers as ‘not only SQL databases’ neither ‘no SQL’, it is an alternative to the most widely used relational databases. As the given name proposed, it is a substitute for SQL that uses in such a way that the SQL is co-existed. A relational database management system (RDBMS) is a database management system based on the relational model of data and it is a completely structured way of storing data. But NoSQL is an unstructured way of storing data. Is NoSQL an RDBMS? This is an article we will discuss various features of NoSQL, various advantages over RDBMS and the future of NoSQL. This article also reviews the basics of NoSQL and its usages.