cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identification of chemical compounds present in different fractions of Annona reticulata L. leaf by using GC–MS
Creators: name: Soumya P. Rout
name: Durga M. Kar
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: Pharmacology
subject: Physiology
subject: Cell Biology
subject: Biochemistry

description: GC–MS analysis of fractions prepared from hydro-alcoholic extract of Annona reticulata Linn (Family Annonaceae) leaf revealed the presence of 9,10-dimethyltricyclo[4.2.1.1(2,5)]decane-9,10-diol; 4-(1,5-dihydroxy-2,6,6-trimethylcyclohex-2-enyl)but-3-en-2-one; 3,7-dimethyl-6-nonen-1-ol acetate; 9-octadecenamide,(Z)-; glycerine; d-glucose,6-O-α-d-galactopyranosyl-; desulphosinigrin and α-methyl-d-mannopyranoside as few of the major compounds in different fractions. The presence of these compounds in the plant has been identified for the first time.
Enhanced rosmarinic acid biosynthesis in Solenostemon scutellarioides culture: a precursor-feeding strategy
Creators: name: Saikat Dewanjee
name: Moumita Gangopadhyay
name: Das, Urmi
name: Ranabir Sahu
name: Khanra, Ritu
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Neuroscience
subject: Molecular Biology
subject: Microbiology
subject: Biochemistry

description: The aim of this study was to employ precursor-feeding strategy for the improved production of rosmarinic acid (RA) in Solenostemon scutellarioides in vitro. The cultures were fed with precursors, namely l-phenylalanine (Phe), l-tyrosine (Tyr) and cucumber juice (CJ), at different concentrations. Phe (100 mg L− 1) and Tyr (400 mg L− 1) caused ∼1.5- and 2.1-fold increase in RA accumulation within 48 h. CJ (50 mg L− 1) feeding displayed highest RA content (∼1.6-fold) in 72 h. In this study, we focused on the function of individual precursor on key enzymes involved in RA biosynthesis. The phenylalanine ammonia lyase activity was significantly upregulated after Phe (100 mg L− 1) feeding, while tyrosine aminotransferase and hydroxyphenylpyruvate reductase activities were improved with Tyr (400 mg L− 1) treatment. However, rosmarinic acid synthase activity was significantly enhanced by all three precursors. In synergy study, Phe (100 mg L− 1) + Tyr (400 mg L− 1) could enhance (∼3.1-fold) RA biosynthesis within 48 h.
Sovereign Wealth Funds and Caribbean Economic Development: Measures Matter
Creators: name: Sharland, Alex
name: Affuso, Ermanno
name: Sharland, Alex
name: Affuso, Ermanno
Publisher: name: Unknown
Year: 2019
Subjects: subject: Financial Economics
subject: International Development
subject: Sovereign Wealth Funds
subject: Economic Development
subject: Caribbean Economies

description: This short paper presents a brief survey of the literature on Sovereign Wealth Funds (SWF) as a potential trigger of economic growth in developing countries. Some authors argue that a stable institutional environment that eases public and private investments could be the primary determinant of growth. Given the limited data availability, we compare the economic statistics of Trinidad and Tobago and Botswana, countries with a SWF, versus Jamaica and Namibia as control counterparts. The paper discusses the possibility that returns on a SWF could lead to sustainable growth if they are invested in human capital formation.
Good practices for the management of pests in Stone Pine (Pinus pinea L.)
Creators: name: Pacheco Marques, Pedro
Publisher: name: Zenodo
Year: 2025
Subjects: Adaptation to climate change
Pest/disease control

description: The project identified pests impacting pine nut production, highlighting major pests like the Western conifer seed bug and pine cone moth, alongside minor ones like the pine processionary. It detailed their life cycles, damage assessments, and recommended mixed forest planting for better management.
Carnet nº 7b, commencé à Tsin-tsi-kar (p. 3)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: created: 7-6-1930
The production of isoflavonoids in Genista tinctoria L. cell suspension culture after abiotic stressors treatment
Creators: name: J. Kubeš
name: L. Tůmová
name: J. Martin
name: A. Vildová
name: H. Hendrychová
name: K. Sojková
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Cancer
subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Cell Biology
subject: Microbiology
subject: Medicine
subject: Biochemistry
subject: Biophysics

description: The increased content of isoflavonoids in dry cell suspension and nutrient medium was observed after application of electric current and AgNO3 on Genista tinctoria L. cultures in vitro. The highest content of genistin (1.7 mg g− 1 DW – dry weight) was measured in the dry cell suspension culture after 30 min elicitation of 10 V and 6 h cultivation and daidzein content (3.5 mg g− 1 DW) was measured after 60 min elicitation of 5 V and 24 h cultivation. In the case of AgNO3 elicitation, the content of genistin in dry cell suspension culture (0.5 mg g− 1 DW) was highest after 48 h of AgNO3 treatment and concentration of 5.9 × 10− 4 mol/L. The AgNO3 concentration of 5.9 × 10− 4 mol/L was also the most effective combination for daidzein production (0.9 mg g− 1 DW) after 168 h. The results of this study show that the secondary metabolites could also be released from G. tinctoria L. cells into the nutrient medium.
LADM based models for sustainable development LD-DRM for disaster prone areas and communities (an example for SDG 1 and SDG 13)
Creators: name: Unger, Eva-Maria
name: Bennett, Rohan
name: Lemmen, Christiaan
name: Zevenbergen, Jaap
name: Dijkstra, Paula
name: de Zeeuw, Kees
Publisher: name: Swinburne
Year: 2024

description: The 2030 Agenda for Sustainable Development with its defined Sustainable Development Goals (SDGs), together with other policies such as the Sendai Framework for Disaster Risk Reduction, or the Voluntary Guidelines on the Responsible Governance of Tenure of Land, Fisheries and Forests in the Context of National Food Security (VGGT) stimulate innovative and transformative approaches to secure land and property rights for all. In regard to SDG 13, the Sendai Framework specifically calls for investments in research and the development of a methodology and models for disaster risk management (DRM). Responsible land administration (LA) and DRM both focus on empowering vulnerable groups to become resilient communities. When LA is implemented responsibly, it underpins good land governance and ultimately supports sustainable LA by providing strategies and tools to document all people-to-land relationships. DRM and especially community-based DRM aims to evaluate and manage natural disaster risks at the local level – and highlight the role of communities when it comes to natural disasters. Disaster prevention, response and recovery require information about land tenure. Though, in many high-risk contexts, such records are non-existent or not up to date. A model, LA-DRM, linking the domains of LA and DRM – with the goal of supporting resilience against natural disasters and providing an approach for collecting data once and using it multiple times addresses this issue. A design approach was used to develop the model – with adaption of the international Land Administration Domain Model (LADM) standard, as published in (ISO, 2012) (Lemmen, 2012), (Hay, 2014), (Lemmen, et al., 2015), acting as a basis. Key features of the model include the support of interoperability through standardisation, the inclusion of all people-to-land relationships including those specific to disaster contexts, and the potential of the model to contribute to each of the disaster phases. The LADM model, and its aggregated models, such as the LA-DRM model, though is suggested to be highly applicable in any land related SDG context where no land tenure information exists, or the national mapping authority already uses a LA system compatible with LADM. Overall, the LA-DRM model is considered as a step towards an implementable strategy for applying responsible LA in e.g. the context of DRM and serves as an example of how to support other SDGs.
Phytochemical analysis and bioactivity of the aerial parts of Abutilon theophrasti (Malvaceae), a medicinal weed
Creators: name: N.Z. Mamadalieva
name: F. Sharopov
name: J.-P. Girault
name: M. Wink
name: R. Lafont
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Cell Biology
subject: Engineering
subject: Biochemistry

description: Phytochemical investigations of aerial parts of Abutilon theophrasti yielded (6S,9R)-roseoside (1) and (6S,9S)-roseoside (2) which are new for the genus. The elucidation of the chemical structures was established by mass spectrometry, 1D and 2D NMR experiments. Although methanol extracts contained 48.5 ± 7.2 mg of caffeic acid equivalents and 15.87 ± 4.6 mg of quercetin equivalents, the antioxidant activity, as revealed by DPPH and ABTS assays, was of medium strength (EC50 of 306.2 ± 16.3 and 394.3 ± 14.8 μg/mL, respectively). A. theophrasti extract inhibits soybean 5-LOX with IC50 value 2.89 ± 0.2 mg/mL. The cytotoxicity of the methanol extract against MCF-7, CCRF-CEM and CEM/ADR5000 cancer cells resulted in IC50 values of 505.8 ± 34.7 μg/mL for MCF-7, 75.6 ± 7.1 μg/mL for CCRF-CEM, and 89.5 ± 13.4 μg/mL for CEM/ADR 5000 cells.
Kinetic Control of Parallel versus Antiparallel Amyloid Aggregation via Shape of the Growing Aggregate
Creators: name: Zanjani, Ali Asghar Hakami
name: Reynolds, Nicholas
name: Zhang, Afang
name: Schilling, Tanja
name: Mezzenga, Raffaele
name: Berryman, Joshua T.
Publisher: name: Swinburne
Year: 2024

description: By combining atomistic and higher-level modelling with solution X-ray diffraction we analyse self-assembly pathways for the IFQINS hexapeptide, a bio-relevant amyloid former derived from human lysozyme. We verify that (at least) two metastable polymorphic structures exist for this system which are substantially different at the atomistic scale, and compare the conditions under which they are kinetically accessible. We further examine the higher-level polymorphism for these systems at the nanometre to micrometre scales, which is manifested in kinetic differences and in shape differences between structures instead of or as well as differences in the small-scale contact topology. Any future design of structure based inhibitors of the IFQINS steric zipper, or of close homologues such as TFQINS which are likely to have similar structures, should take account of this polymorphic assembly.
Entrepreneurship education: the case for adopting the team-based learning approach
Creators: name: Rushworth, Susan
Publisher: name: Swinburne
Year: 2024

description: Entrepreneurship education makes extensive use of experiential learning, but the experiential activities are often not underpinned by established theory, or rely on a narrow base of theory informed by the research interests of the teaching staff (Fiet, 2000a). Students often resist theory classes, perceiving them as boring and irrelevant (Fiet, 2000b). Fiet argued for teaching through a combination of theory and activity, where the relevance of theory is clearly demonstrated through activities based on problems the theory purports to explain or solve. The Team-Based Learning approach (Michaelson, 2002) is a specific technique that facilitates this process, and yet has not been widely adopted by entrepreneurship educators apart from Michaelson himself. This discussion paper compares the TBL process with the pedagogical principles outlined by Fiet, reports a specific experience of using TBL in an integrative business unit, and calls for wider adoption of TBL in entrepreneurship teaching.
title: 02_0027
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Melt pond fractions on Arctic summer sea ice retrieved from Sentinel-3 satellite data with a constrained physical forward model
Creators: name: Niehaus, Hannah
name: Istomina, Larysa
name: Nicolaus, Marcel
name: Tao, Ran
name: Malinka, Aleksey
name: Zege, Eleonora
name: Spreen, Gunnar
Publisher: name: Universität Bremen
Year: 2024
Subjects: subject: sea ice
subject: Arctic
subject: Albedo
subject: satellite remote sensing
subject: melt ponds
subject: 550

description: The presence of melt ponds on Arctic summer sea ice significantly alters its albedo and thereby the surface energy budget and mass balance. Large-scale observations of melt pond coverage and sea ice albedo are crucial to investigate the role of sea ice for Arctic amplification and its representation in global climate models. We present the new Melt Pond Detection 2 (MPD2) algorithm, which retrieves melt pond, sea ice, and open-ocean fractions as well as surface albedo from Sentinel-3 visible and near-infrared reflectances. In contrast to most other algorithms, our method uses neither fixed values for the spectral albedo of the surface constituents nor an artificial neural network. Instead, it aims for a fully physical representation of the reflective properties of the surface constituents based on their optical characteristics. The state vector X, containing the optical properties of melt ponds and sea ice along with the area fractions of melt ponds and open ocean, is optimized in an iterative procedure to match the measured reflectances and describe the surface state. A major problem in unmixing a compound pixel is that a mixture of half open water and half bright ice cannot be distinguished from a homogeneous pixel of darker ice. In order to overcome this, we suggest constraining the retrieval with a priori information. Initial values and constraint of the surface fractions are derived with an empirical retrieval which uses the same spectral reflectances as implemented in the physical retrieval. The snow grain size and optical thickness change with time, and thus the ice surface albedo changes throughout the season. Therefore, field observations of spectral albedo are used to develop a parameterization of the sea ice optical properties as a function of the temperature history of the sea ice. With these a priori data, the iterative optimization is initialized and constrained, resulting in a retrieval uncertainty of below 8 % for melt pond and 9 % for open-ocean fractions compared to the reference dataset. As reference data for evaluation, a 10 m resolution product of melt pond and open-ocean fraction from Sentinel-2 optical imagery is used.
Mechanochemical Formation of Racemic Praziquantel Hemihydrate with Improved Biopharmaceutical Properties.
Creators: name: Zanolla, Debora
name: Hasa, Dritan
name: Arhangelskis, Mihails
name: Schneider-Rauber, Gabriela
name: Chierotti, Michele R
name: Keiser, Jennifer
name: Voinovich, Dario
name: Jones, William
name: Perissutti, Beatrice
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Polymorphism
praziquantel
Mechanochemistry
Racemic Compound
Liquid-assisted Grinding
Neat Grinding
Crystal Structure Solution
Hemihydrate

description: Praziquantel (PZQ) is the first-line drug used against schistosomiasis, one of the most common parasitic diseases in the world. A series of crystalline structures including two new polymorphs of the pure drug and a series of cocrystals of PZQ have been discovered and deposited in the Cambridge Structural Database (CSD). This work adds to the list of multicomponent forms of PZQ a relevant example of a racemic hemihydrate (PZQ-HH), obtainable from commercial PZQ (polymorphic Form A) through mechanochemistry. Noteworthy, the formation of the new hemihydrate strongly depends on the initial polymorphic form of PZQ and on the experimental conditions used. The new PZQ-HH has been fully characterized by means of HPLC, Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Hot-Stage Microscopy (SEM), Powder X-Ray Diffraction (PXRD), Scanning Electron Microscopy (SEM), FT-IR, polarimetry, solid-state NMR (SS-NMR), solubility and intrinsic dissolution rate (IDR), and in vitro tests on Schistosoma mansoni adults. The crystal structure was solved from the powder X-ray diffraction pattern and validated by periodic-DFT calculations. The new bioactive hemihydrate was physically stable for three months and showed peculiar biopharmaceutical features including enhanced solubility and a double intrinsic dissolution rate in water in comparison to the commercially available PZQ Form A.
Entrepreneurs and social capital: strategic leadership in the 21st century firms
Creators: name: Tanas, Janusz
name: Dembek, Krzysztof
name: Gillin, Murray
name: Spring, Stephen F.
Publisher: name: Swinburne
Year: 2024

description: This paper explores the relationships among entrepreneurship, leadership and social capital and its impact on the new face of business. The main hypothesis of this paper is that the rapid absence of well amalgamated aspects of social capital, and entrepreneurship within a society is more likely to produce a lack of leadership and thus, dysfunctional aspects of business. We first reviewed the extant literature in entrepreneurship, social capital and leadership. A more philosophical approach is undertaken to determine what entrepreneurship truly means and how social capital impacts on the natural creation of leadership. The focal point of the argument is that entrepreneurship is the process of the creation of a new business or a growing existing business through an exploration of new opportunities within or outside the existing market space. In order to achieve this objective, nations and institutions have to invest in the overall development of social capital. Thus we argue that social capital is one of the primary resources which need to be developed in order to achieve success of entrepreneurs and therefore leaders. Preliminary findings seem to suggest that a coherence of indicated factors: entrepreneurship and social capital, result in greater leadership ability, thus progress of the business and the overall economy. In addition the study seems to highlight that the dynamism of social capital serves as foundation for entrepreneurship and leadership advancements. We propose a conceptual framework that links entrepreneurship and social capital serving as the main drive for business viability, enhancing progress and a deeper understanding of business feasibility.
Communicating the effectiveness and ineffectiveness of government policies and their impact on public support: a systematic review with meta-analysis.
Creators: name: Reynolds, J P
name: Stautz, K
name: Pilling, M
name: Van Der Linden, S
name: Marteau, T M
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Policy
Communication
Beliefs
Evidence
Attitudes
Acceptability

description: Low public support for government interventions in health, environment and other policy domains can be a barrier to implementation. Communicating evidence of policy effectiveness has been used to influence attitudes towards policies, with mixed results. This review provides the first systematic synthesis of such studies. Eligible studies were randomized controlled experiments that included an intervention group that provided evidence of a policy's effectiveness or ineffectiveness at achieving a salient outcome, and measured policy support. From 6498 abstracts examined, there were 45 effect sizes from 36 eligible studies. In total, 35 (N = 30 858) communicated evidence of effectiveness, and 10 (N = 5078) communicated evidence of ineffectiveness. Random effects meta-analysis revealed that communicating evidence of a policy's effectiveness increased support for the policy (SMD = 0.11, 95% CI [0.07, 0.15], p < 0.0001), equivalent to support increasing from 50% to 54% (95% CI [53%, 56%]). Communicating evidence of ineffectiveness decreased policy support (SMD = -0.14, 95% CI [-0.22, -0.06], p < 0.001), equivalent to support decreasing from 50% to 44% (95% CI [41%, 47%]). These findings suggest that public support for policies in a range of domains is sensitive to evidence of their effectiveness, as well as their ineffectiveness.
title: 03_0626
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Entrepreneurial orientation across the Tasman
Creators: name: Maritz, Alex
Publisher: name: Swinburne
Year: 2024

description: Whilst the Global Entrepreneurship Monitor (GEM: 2005) identifies Australia and New Zealand as having similar rates of total entrepreneurial activity (TEA), introspection into similar business systems across the Tasman are indicative of varying rates of entrepreneurial orientation. This study examines entrepreneurial orientation within a defined franchise system, one in Australia, the other in New Zealand. The objective is to evaluate the degree or rate of entrepreneurial orientation within these two systems, and highlight differences and reasons therefore. Nieman, Hough and Nieuwenhuizen (2003: 11) advise that entrepreneurial orientation is critical to the survival and growth of organisations, notwithstanding the importance to prosperity of economic advantage. They further inform that entrepreneurial orientation is focussed by a unique combination of factors, including culture, role models, family, education, work experience and personal orientation. Personal orientation includes factors such as creativity and innovation, risk taking, autonomy, pro-activeness and achievement orientation.
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.
Creators: name: Hollis, Ben
name: Day, Felix R
name: Busch, Alexander S
name: Thompson, Deborah J
name: Soares, Ana Luiza G
name: Timmers, Paul R H J
name: Kwong, Alex
name: Easton, Doug F
name: Joshi, Peter K
name: Timpson, Nicholas J
name: Ong, Ken K
name: Perry, John R B
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: The timing of puberty is highly variable and is associated with long-term health outcomes. To date, understanding of the genetic control of puberty timing is based largely on studies in women. Here, we report a multi-trait genome-wide association study for male puberty timing with an effective sample size of 205,354 men. We find moderately strong genomic correlation in puberty timing between sexes (rg = 0.68) and identify 76 independent signals for male puberty timing. Implicated mechanisms include an unexpected link between puberty timing and natural hair colour, possibly reflecting common effects of pituitary hormones on puberty and pigmentation. Earlier male puberty timing is genetically correlated with several adverse health outcomes and Mendelian randomization analyses show a genetic association between male puberty timing and shorter lifespan. These findings highlight the relationships between puberty timing and health outcomes, and demonstrate the value of genetic studies of puberty timing in both sexes.
Notes on wh in situ in French
Creators: name: Shlonsky, Ur
Publisher: name: figshare
Year: 2014
Subjects: subject: Linguistics
subject: FOS: Languages and literature

description: Shlonsky, Ur. 2012. Notes on wh in situ in French. In Laura Brugè, Anna Cardinaletti, Giuliana Giusti, Nicola Munaro & Cecilia Poletto (eds.), Functional heads. The cartography of syntactic structures, vol. 7, 242–252. New York: Oxford University Press.http://archive-ouverte.unige.ch/unige:82800
Management and outcomes following emergency surgery for traumatic brain injury - A multi-centre, international, prospective cohort study (the Global Neurotrauma Outcomes Study).
Creators: name: Clark, David
name: Joannides, Alexis
name: Ibrahim Abdallah, Omar
name: Olufemi Adeleye, Amos
name: Hafid Bajamal, Abdul
name: Bashford, Tom
name: Bhebhe, Arnold
name: Biluts, Hagos
name: Budohoska, Natalia
name: Budohoski, Karol
name: Cherian, Iype
name: Marklund, Niklas
name: Fernandez Mendez, Rocio
name: Figaji, Tony
name: Kumar Gupta, Deepak
name: Iaccarino, Corrado
name: Ilunga, Ali
name: Joseph, Mathew
name: Khan, Tariq
name: Laeke, Tsegazeab
name: Waran, Vicknes
name: Park, Kee
name: Rosseau, Gail
name: Rubiano, Andres
name: Saleh, Youssuf
name: Shabani, Hamisi K
name: Smith, Brandon
name: Sichizya, Kachinga
name: Tewari, Manoj
name: Tirsit, Abenezer
name: Thu, Myat
name: Tripathi, Manjul
name: Trivedi, Rikin
name: Villar, Sofia
name: Devi Bhagavatula, Indira
name: Servadei, Franco
name: Menon, David
name: Kolias, Angelos
name: Hutchinson, Peter
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Injuries
Brain injuries
Traumatic
epidemiology
Neurosurgery
Global Health

description: Introduction:Traumatic brain injury (TBI) accounts for a significant amount of death and disability worldwide and the majority of this burden affects individuals in low-and-middle income countries. Despite this, considerable geographical differences have been reported in the care of TBI patients. On this background, we aim to provide a comprehensive international picture of the epidemiological characteristics, management and outcomes of patients undergoing emergency surgery for traumatic brain injury (TBI) worldwide. Methods and analysis:The Global Neurotrauma Outcomes Study (GNOS) is a multi-centre, international, prospective observational cohort study. Any unit performing emergency surgery for TBI worldwide will be eligible to participate. All TBI patients who receive emergency surgery in any given consecutive 30-day period beginning between 1st of November 2018 and 31st of December 2019 in a given participating unit will be included. Data will be collected via a secure online platform in anonymised form. The primary outcome measures for the study will be 14-day mortality (or survival to hospital discharge, whichever comes first). Final day of data collection for the primary outcome measure is February 13th. Secondary outcome measures include return to theatre and surgical site infection. Ethics and dissemination:This project will not affect clinical practice and has been classified as clinical audit following research ethics review. Access to source data will be made available to collaborators through national or international anonymised datasets on request and after review of the scientific validity of the proposed analysis by the central study team.
title: Ανάπλαση πρώην στρατοπέδου Αγίας Παρασκευής : Κέντρο πολιτιστικών εγκαταστάσεων αναψυχής και ευεξίας.
title: Redevelopment of the former St.Paraskevi Camp : Center for cultural recreation and wellness facilities
Creators: name: Μπουραντας Ελευθεριος-Οδυσσεας
Publisher: name: Technical University of Crete
Year: 2024

description: Η παρούσα διπλωματική εργασία αποτελεί πρόταση ανάπλασης του πρώην στρατοπέδου Σπυρούδη στον δήμο Αγίας Παρασκευής Αττικής , αντικαθιστώντας τα υφιστάμενα, ερειπωμένα κτήρια, με μια ζωντανή δομή δικτύου πολιτισμού προσβάσιμη από όλους. Η πρόταση επικεντρώνεται στην ανάγκη της περιοχής μελέτης για την στέγαση χώρων πολιτισμού και στη σύνδεση της με τις υφιστάμενες πολιτιστικές δραστηριότητες. Ο σχεδιασμός αφορά την δημιουργία ενός δημόσιου Κέντρου πολιτισμού με εγκαταστάσεις καλλιτεχνικής έκφρασης σε συνδυασμό με δομές αποφόρτισης και ευεξίας . Βασική πρόθεση ήταν η συσχέτιση της περιοχής μελέτης με τους πρόποδες του Υμηττού και το τοπίο δημιουργώντας ένα κτηριακό σύνολο το οποίο σέβεται το ανάγλυφο και τον χαρακτήρα της γειτονιάς , και έχει ως κύριο στόχο την αναβάθμιση της δημόσιας ψυχικής και σωματικής υγείας, μέσω της τέχνης , του αθλητισμού και της χαλάρωσης.
description: This thesis is a proposal for the reconstruction of the former Spyroudis camp in the municipality of Agia Paraskevi, Attica, replacing the existing, dilapidated buildings with a living cultural network structure accessible to all. The proposal focuses on the need of the study area to accommodate cultural spaces and its connection with existing cultural activities. The design concerns the creation of a public cultural center with facilities for artistic expression combined with relaxation and wellness structures. The main intention was to associate the study area with the foothills of Hymettos and the landscape, creating a building complex that respects the relief and character of the neighborhood, and has as its main objective the upgrading of public mental and physical health, through art, of sports and relaxation.
Factorial Structure and Validity of Depression (PHQ-9) and Anxiety (GAD-7) Scales after Traumatic Brain Injury.
Creators: name: Teymoori, Ali
name: Gorbunova, Anastasia
name: Haghish, Fardzadeh E
name: Real, Ruben
name: Zeldovich, Marina
name: Wu, Yi-Jhen
name: Polinder, Suzanne
name: Asendorf, Thomas
name: Menon, David
name: Center-Tbi Investigators And Participants
name: V Steinbüchel, Nicole
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Depression
Anxiety
Validity
Comorbidity
Bifactorial Model

description: BACKGROUND:The dimensionality of depression and anxiety instruments have recently been a source of controversy. OBJECTIVES AND DESIGN:In a European-wide sample of patients after Traumatic Brain Injury (TBI), we aim to examine the factorial structure, validity, and association of the Patient Health Questionnaire for depression (PHQ-9) and the Generalized Anxiety Disorder (GAD-7) instruments. This study is based on longitudinal observational data. We conducted analyses of factorial structure and discriminant validity of outcomes six-months after TBI. We also examined the prevalence, co-occurrence, and changes of scores on the PHQ-9 and GAD-7 at 3-, 6-, and 12-month post-TBI assessments. PARTICIPANTS:At six-months post-TBI assessment, 2137 (738 (34.5%) women) participants completed the PHQ-9 and GAD-7 questionnaires. For the longitudinal analysis, we had 1922 participants (672 (35.0%) women). RESULTS:The results of exploratory factor analysis suggested a general latent construct underlying both PHQ-9 and GAD-7 measures. Confirmatory factor analyses showed a slight improvement in the fit indices for the bifactorial model. The Omega hierarchical test clearly differentiated two subfactors of PHQ-9 and GAD-7 items over and above the underlying general factor; however, most of the variance (85.0%) was explained by the general factor and the explained variance of the subfactors was small. The PHQ-9 and GAD-7 performed similarly in detecting post-traumatic stress disorder (PTSD). As defined by conventional cut-offs, depression and anxiety have different prevalence rates in the sample. The scales also differed in their relationships with the short form of health survey (SF-36v2) subscales. The longitudinal analysis showed high stability of depression and anxiety symptoms: 49-67% of the post-TBI patients with comorbid depression and anxiety reported the persistence of the symptoms over time. DISCUSSION:The factorial structure analysis favors a general latent construct underlying both depression and anxiety scales among patients after TBI. We discuss the implications our findings and future research directions.
The future of sleep health: a data-driven revolution in sleep science and medicine.
Creators: name: Perez-Pozuelo, Ignacio
name: Zhai, Bing
name: Palotti, Joao
name: Mall, Raghvendra
name: Aupetit, Michaël
name: Garcia-Gomez, Juan M
name: Taheri, Shahrad
name: Guan, Yu
name: Fernandez-Luque, Luis
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Sleep
Biomedical engineering
Preventive Medicine
Diagnostic Markers
Predictive Markers

description: In recent years, there has been a significant expansion in the development and use of multi-modal sensors and technologies to monitor physical activity, sleep and circadian rhythms. These developments make accurate sleep monitoring at scale a possibility for the first time. Vast amounts of multi-sensor data are being generated with potential applications ranging from large-scale epidemiological research linking sleep patterns to disease, to wellness applications, including the sleep coaching of individuals with chronic conditions. However, in order to realise the full potential of these technologies for individuals, medicine and research, several significant challenges must be overcome. There are important outstanding questions regarding performance evaluation, as well as data storage, curation, processing, integration, modelling and interpretation. Here, we leverage expertise across neuroscience, clinical medicine, bioengineering, electrical engineering, epidemiology, computer science, mHealth and human-computer interaction to discuss the digitisation of sleep from a inter-disciplinary perspective. We introduce the state-of-the-art in sleep-monitoring technologies, and discuss the opportunities and challenges from data acquisition to the eventual application of insights in clinical and consumer settings. Further, we explore the strengths and limitations of current and emerging sensing methods with a particular focus on novel data-driven technologies, such as Artificial Intelligence.
Notes on wh in situ in French
Creators: name: Shlonsky, Ur
Publisher: name: figshare
Year: 2016
Subjects: subject: Linguistics
subject: FOS: Languages and literature

description: Shlonsky, Ur. 2012. Notes on wh in situ in French. In Laura Brugè, Anna Cardinaletti, Giuliana Giusti, Nicola Munaro & Cecilia Poletto (eds.), Functional heads. The cartography of syntactic structures, vol. 7, 242–252. New York: Oxford University Press.http://archive-ouverte.unige.ch/unige:82800
An analytical model of MAC access delay in IEEE 802.11e EDCA
Creators: name: Xu, Dongxia
name: Sakurai, Taka
name: Vu, Hai
Publisher: name: Swinburne
Year: 2024

description: In this paper, we study the MAC access delay of EDCA in the draft IEEE 802.11e standard under saturated conditions. We obtain explicit expressions for the mean, the standard deviation and the generating function of the distribution of the access delay. By using numerical inversion on the generating function, we are able to compute values of the distribution. We show that our analytical model has high accuracy via comparison with simulation.
Notes on wh in situ in French
Creators: name: Shlonsky, Ur
Publisher: name: figshare
Year: 2014
Subjects: subject: Linguistics
subject: FOS: Languages and literature

description: Shlonsky, Ur. 2012. Notes on wh in situ in French. In Laura Brugè, Anna Cardinaletti, Giuliana Giusti, Nicola Munaro & Cecilia Poletto (eds.), Functional heads. The cartography of syntactic structures, vol. 7, 242–252. New York: Oxford University Press.
Flexible Nets: a modeling formalism for dynamic systems with uncertain parameters.
Creators: name: Júlvez, Jorge
name: Oliver, Stephen G
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: performance analysis
Dynamic Systems
Petri Nets
Modeling Formalisms
Uncertain Parameters
Flexible Nets

description: The modeling of dynamic systems is frequently hampered by a limited knowledge of the system to be modeled and by the difficulty of acquiring accurate data. This often results in a number of uncertain system parameters that are hard to incorporate into a mathematical model. Thus, there is a need for modeling formalisms that can accommodate all available data, even if uncertain, in order to employ them and build useful models. This paper shows how the Flexible Nets (FNs) formalism can be exploited to handle uncertain parameters while offering attractive analysis possibilities. FNs are composed of two nets, an event net and an intensity net, that model the relation between the state and the processes of the system. While the event net captures how the state of the system is updated by the processes in the system, the intensity net models how the speed of such processes is determined by the state of the system. Uncertain parameters are accounted for by sets of inequalities associated with both the event net and the intensity net. FNs are not only demonstrated to be a valuable formalism to cope with system uncertainties, but also to be capable of modeling different system features, such as resource allocation and control actions, in a facile manner.
Out-migration: Young Victorians and the family farm
Creators: name: Geldens, Paula
Publisher: name: Swinburne
Year: 2024

description: Studies of the out migration of young people from rural areas rely heavily on the push and pull factors of the need to move for higher education and jobs. But the broad brush picture these studies provide misses much of the complexity of the young people's decision making. Questionnaire data and interviews with young people living on family farms in Victoria show that many would like to stay, but the fear of being seen to be a failure is a powerful force goading them to move, irrespective of their personal wishes.
Cuttlefish retrieve whether they smelt or saw a previously encountered item.
Creators: name: Billard, P
name: Clayton, N S
name: Jozet-Alves, C
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: According to the Source Monitoring Framework, the origin of a memory is remembered through the retrieval of specific features (e.g. perceptive, sensitive, affective signals). In two source discrimination tasks, we studied the ability of cuttlefish to remember the modality in which an item had been presented several hours ago. In Experiment 1, cuttlefish were able to retrieve the modality of presentation of a crab (visual vs olfactory) sensed before 1 h and 3 hrs delays. In Experiment 2, cuttlefish were trained to retrieve the modality of the presentation of fish, shrimp, and crabs. After training, cuttlefish performed the task with another item never encountered before (e.g. mussel). The cuttlefish successfully passed transfer tests with and without a delay of 3 hrs. This study is the first to show the ability to discriminate between two sensory modalities (i.e. see vs smell) in an animal. Taken together, these results suggest that cuttlefish can retrieve perceptual features of a previous event, namely whether they had seen or smelled an item.
Entrepreneurial market entry: a franchising perspective in Saudi Arabia
Creators: name: Maritz, Alex
name: Abughazala, Harry
name: Frederick, Howard
Publisher: name: Swinburne
Year: 2024

description: As franchise systems mature in their domestic markets, franchisors wishing to expand their operations need to look to international markets. Amos (2001) believes franchisors must have a strategic plan that incorporates international opportunities as we move closer to a global marketplace and global economy. Despite government bodies in countries such as Malaysia and Singapore opening doors to franchising, a country's regulatory framework as well as the government's actions or inactions can foster or hinder franchise development in any nation. The aim of this study is to evaluate the numerous barriers to the internationalization of franchising, and qualify this in the context of franchising in the Kingdom of Saudi Arabia. The purpose is to explore possible entrepreneurial modes of entry for Australasian franchise systems into Saudi Arabia. After joining the World Trade Organization, Saudi Arabia has been identified as lucrative compared to other markets in the Middle East region. We specifically concentrate on the fast-food industry, as the business sectors experiencing the most franchise growth internationally are retail and restaurants (Hoffman & Preble, 2004).
The post-public sphere and neo-regulation of digital platforms
Creators: name: Schlesinger, Philip
Publisher: name: CREATe
Year: 2024

description: This article discusses the post-public sphere and the regulation of platforms that have had disruptive effects on democracy. Platformisation means that the normative ideals for a political public sphere set out by Jürgen Habermas face a distinctive challenge. “Neo-regulation” is an evolving adaption by states that reflects the urgent need to address platformisation and digitalisation more generally. In conditions of geopolitical competition, notably between the China and US, attempts by various states and the EU to establish a neo-regulatory order has developed a significant national security dimension, which is highly relevant for the regulation of digital communication. Policing borders and content is an ever-present focus in all political regimes, whether characterised as democratic or authoritarian. Applying Pierre Bourdieu’s field theory to internet regulation, the argument is illustrated by reference to current British regulatory practice. At the level of the state, the “regulatory field” is shaped by national and global forces. Although the British case has specific characteristics, the underlying analysis has general relevance for comparative research.
The use of data for the internationalisation of Higher Education
Creators: name: eQuatic Consortium
Publisher: name: European University Foundation
Year: 2019

description: eQuATIC project researched on how to use data to improve the quality and processes of setting up, maintaining and terminating inter institutional agreements.

The eQuATIC project is based on the initial efforts of Ghent University to strengthen their decision-making process for inter-institutional partners for student mobility based on data. Through a pilot project co-funded by the Flemish Ministry of Higher Education, the project developed, in cooperation with multiple Flemish Higher Education Institutions, an analysis tool for the quality of partnerships and allowed the abovementioned consortium to learn both from the research data presented in this paper, as well as from the practical experiences of the pilot project.
Buddy Rich, Twelfth Annual Stony Brook Music Festival Program, July 22, 1967
Creators: name: Stony Brook Community Fund
Publisher: name: Unknown
Year: 1967
Subjects: Stony Brook
Amphitheaters
Programs
Music festivals

description: This is the Twelfth Annual Stony Brook Music Festival Program, July 22, 1967. Program highlights the July 22nd headliner, Buddy Rich and The Buddy Rich Orchestra. American jazz drum virtuoso who accompanied major big bands before forming his own popular big band in the 1960s.
Avoidant Coping Style to High Imminence Threat Is Linked to Higher Anxiety-Like Behavior.
Creators: name: Quah, Shaun K L
name: Cockcroft, Gemma J
name: McIver, Lauren
name: Santangelo, Andrea M
name: Roberts, Angela C
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Stress
Anxiety
threat
emotion
Fear
Coping

description: Human studies with self-reported measures have suggested a link between an avoidant coping style and high anxiety. Here, using the common marmoset as a model, we characterize the latent factors underlying behavioral responses of these monkeys towards low and high imminence threat and investigate if a predominantly avoidant behavioral response to high imminence threat is associated with greater anxiety-like behavior in a context of low imminence threat. Exploratory factor analysis (EFA) of the human intruder test of low imminence threat revealed a single factor in which a combination of active vigilance and avoidance responses underpinned anxiety-like behavior. In contrast, two negatively-associated factors were revealed in the model snake test reflecting active and avoidant coping to high imminence threat. Subsequent analysis showed that animals with a predominantly avoidant coping style on the model snake test displayed higher anxiety-like behavior on the human intruder test, findings consistent with those described in humans. Together they illustrate the richness of the behavioral repertoire displayed by marmosets in low and high imminence threatening contexts and the additional insight that factor analysis can provide by identifying the latent factors underlying these complex behavioral datasets. They also highlight the translational value of this approach when studying the neural circuits underlying complex anxiety-like states in this primate model.