cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Drosophila chaetopeza Hardy 1965
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila chaetopeza

description: Drosophila chaetopeza Hardy, 1965
 Synonyms: Drosophila odontostoma Kam and Pereira, in O’Grady et al. 2003b
Distribution: Endemic: Hawaii
 Additional References: Hardy et al. (1981); Heed (1968); Magnacca et al. (2008); Magnacca & O’Grady (2006); Throckmorton (1966)
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 42, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841
title: An extensible modular recognition concept that makes activity recognition practical
Creators: name: Berchtold, Martin
name: Budde, Matthias
name: Schmidtke, Hedda
name: Beigl, Michael
Publisher: name: Universitätsbibliothek Braunschweig
Year: 2010
Subjects: subject: 004

description: In mobile and ubiquitous computing, there is a strong need for supporting different users with different interests, needs, and demands. Activity recognition systems for context aware computing applications usually employ highly optimized off-line learning methods. In such systems, a new classifier can only be added if the whole recognition system is redesigned. For many applications that is not a practical approach. To be open for new users and applications, we propose an extensible recognition system with a modular structure.We will show that such an approach can produce almost the same accuracy compared to a system that has been generally trained (only 2 percentage points lower). Our modular classifier system allows the addition of new classifier modules. These modules use Recurrent Fuzzy Inference Systems (RFIS) as mapping functions, that not only deliver a classification, but also an uncertainty value describing the reliability of the classification. Based on the uncertainty value we are able to boost recognition rates. A genetic algorithm search enables the modular combination.
A geometrical origin for the covariant entropy bound
Creators: name: Casini, H.
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Causal diamond-shaped subsets of space-time are naturally associated with operator algebras in quantum field theory, and they are also related to the Bousso covariant entropy bound. In this work we argue that the net of these causal sets to which are assigned the local operator algebras of quantum theories should be taken to be non orthomodular if there is some lowest scale for the description of space-time as a manifold. This geometry can be related to a reduction in the degrees of freedom of the holographic type under certain natural conditions for the local algebras. A non orthomodular net of causal sets that implements the cutoff in a covariant manner is constructed. It gives an explanation, in a simple example, of the non positive expansion condition for light-sheet selection in the covariant entropy bound. It also suggests a different covariant formulation of entropy bound.
description: 20 pages, 8 figures, final version
Drosophila furvifacies Hardy 1965
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila furvifacies

description: Drosophila furvifacies Hardy, 1965
Distribution: Endemic: Oahu, Kauai, possibly Molokai
 Additional References: Hardy & Kaneshiro (1975b); Magnacca & O’Grady (2009); O’Grady et al. (2011); Throckmorton (1966)
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 44, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841
Exact Two-Point Correlation Functions of Turbulence Without Pressure in Three-Dimensions
Creators: name: Rastegar, A. R.
name: Tabar, M. R. Rahimi
name: Hawaii, P.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Chaotic Dynamics (nlin.CD)
subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We investigate exact results of isotropic turbulence in three-dimensions when the pressure gradient is negligible. We derive exact two-point correlation functions of density in three-dimensions and show that the density-density correlator behaves as $ |{x_1 - x_2}|^{-α_3}$, where $α_3 = 2 + \frac{\sqrt{33}}{6}$. It is shown that, in three-dimensions, the energy spectrum $E(k)$ in the inertial range scales with exponent $ 2 - \frac {\sqrt{33}}{12} \simeq 1.5212$. We also discuss the time scale for which our exact results are valid for strong 3D--turbulence in the presence of the pressure. We confirm our predictions by using the recent results of numerical calculations and experiment.
description: 9 pages, latex, no figures, we have corrected the our basic equations. We predict the inertial-range exponent for the energy spectrum for 3D-turbulence without pressure. We will present the detail of calculation and the results for 2D-turbulence elsewhere. Also some references are added
Additional file 1 of Rare disease awareness and perspectives of physicians in China: a questionnaire-based study
Creators: name: Li, Xuefeng
name: Zhang, Xiangyu
name: Zhang, Shu
name: Lu, Zijuan
name: Zhang, Jianyong
name: Zhou, Jincheng
name: Li, Bingzhe
name: Ou, Li
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Mental Health

description: Additional file 1. List of questions.
اصلاح قانون به‌کارگیری نخبگان جایگزین خدمت خارج از کشور بنیاد ملی نخبگان
Creators: name: AmirMohammad Abhary
Publisher: name: figshare
Year: 2019
Subjects: Uncategorized

description: از جمله اقدامات مناسب سال‌های اخیر بنیاد ملی نخبگان برنامه‌های جذب و به‌کارگیری ایرانیان خارج از کشور بوده ست. در این راستا بنیاد اجازه می‌دهد تا افرادی که در 400 دانشگاه برتر دنیا تحصیل نموده و حداقل مدرک کارشناسی ارشد دارند و حائز حداقل امتیازات مشخصی باشند، همانند نخبگان داخل کشور به استفاده از برنامه‌های جایگزین خدمت بپردازند. در این بین اما تبصره 3 ماده 2 شرایط مشمولان اعلام می‌دارد که در دوره خدمت نظام‌وظیفه تخصصی، فرد باید در ایران حضور داشته و مجاز نیست به تحصیل اشتغال داشته باشد. به نظر می‌رسد قید الزام به حضور در کشور از جهاتی برنامه‌های پیش رو را دچار مشکل نماید.
Distributed Algorithms for Fully Personalized PageRank on Large Graphs
Creators: name: Lin, Wenqing
Publisher: name: arXiv
Year: 2019
Subjects: subject: Social and Information Networks (cs.SI)
subject: Databases (cs.DB)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: Personalized PageRank (PPR) has enormous applications, such as link prediction and recommendation systems for social networks, which often require the fully PPR to be known. Besides, most of real-life graphs are edge-weighted, e.g., the interaction between users on the Facebook network. However, it is computationally difficult to compute the fully PPR, especially on large graphs, not to mention that most existing approaches do not consider the weights of edges. In particular, the existing approach cannot handle graphs with billion edges on a moderate-size cluster. To address this problem, this paper presents a novel study on the computation of fully edge-weighted PPR on large graphs using the distributed computing framework. Specifically, we employ the Monte Carlo approximation that performs a large number of random walks from each node of the graph, and exploits the parallel pipeline framework to reduce the overall running time of the fully PPR. Based on that, we develop several optimization techniques which (i) alleviate the issue of large nodes that could explode the memory space, (ii) pre-compute short walks for small nodes that largely speedup the computation of random walks, and (iii) optimize the amount of random walks to compute in each pipeline that significantly reduces the overhead. With extensive experiments on a variety of real-life graph datasets, we demonstrate that our solution is several orders of magnitude faster than the state-of-the-arts, and meanwhile, largely outperforms the baseline algorithms in terms of accuracy.
description: Full Research Paper accepted in the proceedings of the 30th World Wide Web Conference (WWW 2019)
Regularized Stochastic Block Model for robust community detection in complex networks
Creators: name: Lu, Xiaoyan
name: Szymanski, Boleslaw K.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Social and Information Networks (cs.SI)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: The stochastic block model is able to generate different network partitions, ranging from traditional assortative communities to disassortative structures. Since the degree-corrected stochastic block model does not specify which mixing pattern is desired, the inference algorithms, which discover the most likely partition of the networks nodes, are likely to get trapped in the local optima of the log-likelihood. Here we introduce a new model constraining nodes' internal degrees ratios in the objective function to stabilize the inference of block models from the observed network data. Given the regularized model, the inference algorithms, such as Markov chain Monte Carlo, reliably finds assortative or disassortive structure as directed by the value of a single parameter. We show experimentally that the inference of our proposed model quickly converges to the desired assortative or disassortative partition while the inference of degree-corrected stochastic block model gets often trapped at the inferior local optimal partitions when the traditional assortative community structure is not strong in the observed networks.
Investigations into the Development of Epothilones as Antibody-Drug Conjugate Payloads
Creators: Imlay, Hunter David
Publisher: name: Columbia University
Year: 2020
Subjects: Chemistry, Organic
Chemistry
Antineoplastic agents
Cancer cells--Effect of drugs on
Therapeutics

description: Cytotoxic natural products represent a class of cancer drug candidates that have remained largely untapped as payloads in the antibody-drug conjugate (ADC) therapeutic modality. The epothilones, a class of exquisitely cytotoxic natural products and their synthetic analogs, are a prime example, and our work has focused on the development of epothilones as ADC payloads. Strategies toward this goal have included total synthetic efforts toward four structurally distinct epothilone analogs equipped with linker functionality and structural modifications designed to improve metabolic and chemical stability. In addition, we have pursued the synthesis of octreotide- epothilone conjugates, structures designed to target epothilones into cells that overexpress somatostatin receptors 2 and 5. Biological evaluation via in vitro cellular assays revealed one of our epothilone analogs as a promising epothilone-inspired ADC payload. Synthetic efforts toward these goals will be discussed.
Investigations into roles for endocytosis in LIN-12/Notch signaling and its regulation
Creators: Chan, Jessica Yu
Publisher: name: Columbia University
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Endocytosis
subject: Ligands (Biochemistry)
subject: Caenorhabditis elegans
subject: Vulva
subject: Cellular signal transduction

description: The LIN-12/Notch signaling pathway is highly conserved in all animals, and is crucial for proper development. It is a key pathway in specifying cell fate in many cellular contexts, and dysregulation of the pathway can have deleterious consequences. Therefore, understanding how LIN-12/Notch signaling is regulated in different contexts has been a main area of interest in the field. Previous studies in different model organisms have identified many modes of regulation of the signaling pathway, one of which is endocytosis of the ligand and receptor. Here, I further investigated the role of endocytosis in LIN-12/Notch signaling in multiple developmental contexts in Caenorhabditis elegans. Work in Drosophila and vertebrates had previously established that ligand-mediated activation of Notch requires ubiquitination of the intracellular domain of the transmembrane ligand and the activity of the endocytic adaptor Epsin in the signaling cell. The consensus in the field is that Epsin-mediated endocytosis of mono-ubiquitinated ligand generates a pulling force that exposes a cleavage site in Notch for an ADAM protease, a critical step in signal transduction. In contrast, in this thesis, I examined two different transmembrane ligands in several different cell contexts and found that activation of LIN-12/Notch and the paralogous GLP-1/Notch in C. elegans does not require either Epsin-mediated endocytosis or ubiquitination of the intracellular domain of the ligand. Results obtained by a collaborator indicate that C. elegans ligand and receptor interactions are tuned to a lower force threshold than are Drosophila ligand and receptor interactions, potentially accounting for these differences. I also looked at the role of endocytosis in regulating LIN-12 signaling in the context of vulval development. The cell fate pattern of six vulval precursor cells (VPCs) is mediated by EGFR and LIN-12/Notch signaling. Previous work using multicopy transgenes in fixed specimens indicated that LIN-12 is post-translationally downregulated via endocytosis in response to EGFR activation in the VPC named P6.p, an event that appeared essential for ligands to activate LIN-12/Notch in neighboring VPCs. In this thesis, I manipulate the endogenous lin-12 gene and examine live specimens to show that LIN-12 appears to be regulated transcriptionally in P6.p and evidence that there may be additional potential endocytic motifs that may regulate LIN-12 in this context.
Investigations into the Metabolic Requirements for Lipoic Acid and Lipid Species During the Life Cycle of the Malarial Parasite Plasmodium Berghei
Creators: Falkard, Brie
Publisher: name: Columbia University
Year: 2013
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Plasmodium

description: Plasmodium, like many other pathogenic organisms, relies on a balance of synthesis and scavenging of lipid species for replication. How the parasite creates this balance is particularly important to successfully intervene in transmission of the disease and to generate new chemotherapies to cure infections. This study focuses on two specific aspects in the field of lipid biology of Plasmodium parasites and their hosts. Lipoic acid is a short eight-carbon chain that serves a number of different functions with the cell. By disrupting a key enzyme in the lipoic acid synthesis pathway in the rodent species of malaria, Plasmodium berghei, we sought to investigate its role during the parasite life-cycle. Deletion of the lipoyl-octanoyl transferase enzyme, LipB in P. berghei parasites demonstrate a liver-stage specific need for this metabolic pathway. In order to explore the impact of the fatty acid and triglyceride content on the pathogenesis of Plasmodium parasites, this study tests two methods to reduce lipid content in vivo and test the propagation of P. berghei parasite in these environments. Results from this study set forth new avenues of research with implications for the development of novel antimalarials and vaccine candidates.
title: "Die Notwendigkeit, das zu machen, ist ungebrochen" : Professor Michael Wettern und die Studie „Opfer nationalsozialistischer Verfolgung an der Technischen Hochschule Braunschweig 1930 bis 1945" / von Lars Strominski
Creators: name: Strominski, Lars
Publisher: name: Universitätsarchiv
Year: 2010
Subjects: subject: 940

description: In den Jahren 1930 bis 1945 wurden mehr als fünfzig Hochschulangehörige teils aus rassistischen, doch hauptsächlich aus politischen Gründen an der Technischen Hochschule Braunschweig verfolgt. Am 24. Juni 2010 gedenkt die TU in feierlichem Rahmen dieser Opfer. Präsentiert wird außerdem die von Michael Wettern und Daniel Weßelhöft erarbeitete Studie "Opfer nationalsozialistischer Verfolgung an der Technischen Hochschule Braunschweig 1930 bis 1945".
کسر/جایگزین خدمت در قالب فرصت‌های مطالعاتی و پسادکتری اعزام به خارج از کشور
Creators: name: AmirMohammad Abhary
Publisher: name: figshare
Year: 2019
Subjects: Uncategorized

description: اغلب دانشجویان دکتری در طول تحصیل به دوره فرصت مطالعاتی به‌عنوان فرصتی طلایی جهتت افزایش سطح توانمندی خود نمی‌نگرند. همچنین بسیاری از افراد نیز تحت عنوان پسادکتری به کشورهای خارجی و دانشگاه‌ها و پژوهشگاه‌های آنان اعزام می‌شوند. طبیعتاً در بین این افراد مشمولان سربازی نیز وجود دارد. می‌توان از این فرست جهت اعطای کسر/ جایگزین خدمت و پیش بردن اهداف تحقیقاتی کشور با آخرین تحولات روز دنیا استفاده نمود.
Investigations into pathophysiologic mechanisms and treatment of primary mitochondrial diseases
Creators: Siegmund, Stephanie
Publisher: name: Columbia University
Year: 2018
Subjects: Molecular biology
Mitochondrial pathology
Rapamycin
Biology

description: The present work addresses outstanding questions within the field of primary mitochondrial disease biology and treatment, by incorporating methods from structural biology, molecular biology, and animal studies. First, we utilize a mouse model of mitochondrial deoxyribose nucleic acid (mtDNA) disease to demonstrate the potential therapeutic benefit of low-dose chronic rapamycin treatment. Interestingly, rapamycin therapy significantly extends survival, but does so in the absence of correcting the underlying mitochondrial defect. Next, we focus on human cellular models of mtDNA-based diseases, and show that rapamycin treatment does not induce mitochondrial quality control-mediated clearance of pathogenic mtDNA mutation-harboring organelles. Finally, we investigate a mitochondrial disease phenotype at the level of the organelle, by utilizing in situ cryo-electron tomography to demonstrate the ultrastructural consequences of a pathogenic mutation affecting mitochondrial energy production. We conclude by highlighting the insights into disease biology and treatment that can be gained through a multi-level approach integrating techniques from multiple biomedical fields.
Note on a solution to domain wall problem with the Lazarides-Shafi mechanism in axion dark matter models
Creators: name: Chatterjee, Chandrasekhar
name: Higaki, Tetsutaro
name: Nitta, Muneto
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Axion is a promising candidate of dark matter. After the Peccei-Quinn symmetry breaking, axion strings are formed and attached by domain walls when the temperature of the universe becomes comparable to the QCD scale. Such objects can cause cosmological disasters if they are long-lived. As a solution for it, the Lazarides-Shafi mechanism is often discussed through introduction of a new non-Abelian (gauge) symmetry. We study this mechanism in detail and show configuration of strings and walls. Even if Abelian axion strings with a domain wall number greater than one are formed in the early universe, each of them is split into multiple Alice axion strings due to a repulsive force between the Alice strings even without domain wall. When domain walls are formed as the universe cools down, a single Alice string can be attached by a single wall because a vacuum is connected by a non-Abelian rotation without changing energy. Even if an Abelian axion string attached by domain walls are created due to the Kibble Zurek mechanism at the chiral phase transition, such strings are also similarly split into multiple Alice strings attached by walls in the presence of the domain wall tension. Such walls do not form stable networks since they collapse by the tension of the walls, emitting axions.
description: 20 pages, 10 figures
Field Survey of Chichester Harbour, 1982
Creators: name: Cartwright, Caroline R
Publisher: name: Archaeology Data Service
Year: 2021

description: Sussex Archaeological Collections, 122, 23-27
description: The coastline in Chichester Harbour from West Wittering to the west side of Thorney Island near Emsworth was systematically fieldwalked for evidence of saltmarsh utilization. A total of 72 sites were located along the tidal margins of the foreshore. Most yielded occupation / industrial debris in the form of much flintwork, largely Neolithic in character, with high proportions of scrapers. Other tools, waste material, cores, and hearth-like areas of fire-cracked flint were also much in evidence. Pottery sherds, mostly dating from the Iron Age and Roman periods, were also found. An important concentration of Iron Age and Romano-British material from an industrial and occupation site was located on Thorney Island near Prinsted. Erosion by the sea has resulted in the general spread of archaeological material along the foreshore of the Chichester Harbour area.
تأمین نیروهای فصلی و کارکنان تخصصی صنایع و مراکز تولیدی و خدماتی از سربازان
Creators: name: AmirMohammad Abhary
Publisher: name: figshare
Year: 2019
Subjects: Uncategorized

description: تأمین نیرو برای هر شرکت و واحد تولیدی و خدماتی مستلزم تأمین هزینه‌های بیمه، حقوق و همچنین فرآیندهای مصاحبه، احراز شایستگی و ... است که همگی این‌ها علاوه بر زمان‌بر بودن، هزینه‌های بسیاری را نیز برای آن صنعت در بر دارد. از طرفی دیگر همه‌ساله هزاران نفر سرباز در کشور به‌کارگیری می‌شوند که بخش بزرگی از آنان در عمل به دلیل نبود کارهای متناسب، وقتشان به بطالتی می‌گذرد و عملاً نیروهای مسلح نیز برای ساماندهی آنان دچار مشکل می‌شود. همچنین برای پرداخت حقوق ایشان نیز علی‌رغم تاییدات قانونی، همه‌ساله شاهد پرداخت یک چندم میزان پرداختی مصوب به رده‌های مختلف خدمتی به دلیل عدم تأمین بودجه هستیم. می‌توان با برنامه‌ریزی مناسب، مازاد نیروها را ساماندهی و در مشاغل به کار گفت.
Roman Tileworks at Itchingfield
Creators: name: Green, T K
Publisher: name: Archaeology Data Service
Year: 2021

description: Sussex Archaeological Collections, 108, 23-38
description: A Roman tileworks operated here, perhaps during the 2nd century A.D., serving the needs of the settlement and posting station at Alfoldean on Stanestreet, 2 1/2 miles away. It was possible to examine the tilemakers' workshop and integral drying area, which was built some time after tilemaking had begun. Evidence suggests that, at this site, two combs were in simultaneous use for marking the keying grooves on flue-tiles. Features detected by proton gradiometer survey turned out to be dumps of tile debris.
Nearly Instantaneous Alternatives in Quantum Mechanics
Creators: name: Micanek, Richard J.
name: Hartle, James B.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Quantum Physics (quant-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Usual quantum mechanics predicts probabilities for the outcomes of measurements carried out at definite moments of time. However, realistic measurements do not take place in an instant, but are extended over a period of time. The assumption of instantaneous alternatives in usual quantum mechanics is an approximation whose validity can be investigated in the generalized quantum mechanics of closed systems in which probabilities are predicted for spacetime alternatives that extend over time. In this paper we investigate how alternatives extended over time reduce to the usual instantaneous alternatives in a simple model in non-relativistic quantum mechanics. Specifically, we show how the decoherence of a particular set of spacetime alternatives becomes automatic as the time over which they extend approaches zero and estimate how large this time can be before the interference between the alternatives becomes non-negligible. These results suggest that the time scale over which coarse grainings of such quantities as the center of mass position of a massive body may be extended in time before producing significant interference is much longer than characteristic dynamical time scales.
description: 12 pages, harvmac, no figures
Drosophila amydrospilota Hardy 1965
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila amydrospilota

description: Drosophila amydrospilota Hardy, 1965
 Synonyms: Drosophila vicaria Hardy, 1965
Distribution: Endemic: Maui, Molokai
 Additional References: Heed (1968); Magnacca et al. (2008); Magnacca & O’Grady (2006)
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 39, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841
Monotonicity of the principal eigenvalue for a linear time-periodic parabolic operator
Creators: name: Liu, Shuang
name: Lou, Yuan
name: Peng, Rui
name: Zhou, Maolin
Publisher: name: arXiv
Year: 2019
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: Primary 35P15, Secondary 35K87, 35B10

description: We investigate the effect of frequency on the principal eigenvalue of a time-periodic parabolic operator with Dirichlet, Robin or Neumann boundary conditions. The monotonicity and asymptotic behaviors of the principal eigenvalue with respect to the frequency parameter are established. Our results prove a conjecture raised by Hutson, Michaikow and Poláčik [2001 J. Math. Biol.].
description: 11 pages, 0 figures
Investigations of 12α-Hydroxylated Bile Acid Signaling in Intestinal Organoids
Creators: Ahmad, Tiara Rinjani
Publisher: name: Columbia University
Year: 2019
Subjects: subject: Pathology
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular biology
subject: Bile acids--Metabolism
subject: Intestines--Metabolism

description: Bile acids (BAs) comprise a diverse group of cholesterol metabolites with multiple modes of action. Much of the role of BAs and their receptors in energy homeostasis has been discerned from studies on genetic and/or pharmacologic manipulations. Additionally, changes in BA metabolism and transport have been reported in settings of insulin resistance, obesity, and liver dysfunction. Thus, BA-based interventions have been proposed for treatment of metabolic diseases. However, the heterogeneity of endogenous BAs lends to different affinities for and potencies in activating the various BA receptors, and the effects of altering BA composition per se are incompletely understood. In this dissertation, we aimed to characterize the effects of altering BA composition by stimulating intestinal organoids with distinct BA pools modeled after those in humans and mice. Unexpectedly, we found that BA composition regulated expression of the manganese transporter encoded by Slc30a10 and manganese efflux from cells, suggesting a role for BAs in metal homeostasis. We also identified genes that were similarly and differentially regulated by the distinct mouse and human BA pools. Overall, our studies reveal a pathway by which BAs could modulate micronutrient metabolism, which might also mediate known effects of BAs on macronutrient metabolism.
Gorensteinness of invariant subrings of quantum algebras
Creators: name: Jing, Naihuan
name: Zhang, James J.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Rings and Algebras (math.RA)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 16E10, 16S80, 16W50

description: We prove Auslander-Gorenstein and $\GKdim$-Macaulay properties for certain invariant subrings of some quantum algebras, the Weyl algebras, and the universal enveloping algebras of finite dimensional Lie algebras.
description: AMSTEX, 18 pages. Revised and corrected version
The Mixmaster Universe in Five Dimensions
Creators: name: Halpern, Paul
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider a five dimensional vacuum cosmology with Bianchi type-IX spatial geometry and an extra non-compact coordinate. Finding a new class of solutions, we examine and rule out the possibility of deterministic chaos. We interpret this result within the context of induced matter theory.
description: 13 pages
title: Einführung in die internationalen Beziehungen (IB): Foliensatz zur Vorlesung im SS 2007
Creators: name: Menzel, Ulrich
Publisher: name: Institut für Sozialwissenschaften (ISW)
Year: 2007
Subjects: subject: 327

description: Forschungsberichte aus dem Institut für Sozialwissenschaften (ISW), vol. 81
اعطای جایگزین خدمت به دانشجویان و فارغ‌التحصیلان دکتری و پسادکتری در رشته‌های نوین
Creators: name: AmirMohammad Abhary
Publisher: name: figshare
Year: 2019
Subjects: Uncategorized

description: علی‌رغم توسعه کیفی و کمی دانشگاه‌ها و پژوهشگاه‌های کشور، هنوز رشته‌ها و گرایش‌های جدیدی هستند که در کشور وجود ندارند. از طرفی بخشی از دانشجویان و فارغ‌التحصیلان کشور که مشمول خدمت وظیفه عمومی هستند نیز در این رشته‌ها تحصیل نموده‌اند. می‌توان جهت بهره‌مندی از فرصت سربازی به‌عنوان مؤلفه توسعه علمی و عملی کشور، از این افراد جهت ایجاد و گسترش این رشته‌ها حمایت نمود.
Testing the Gravitational Weak Equivalence Principle in the Standard-Model Extension with Binary Pulsars
Creators: name: Shao, Lijing
name: Bailey, Quentin G.
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The Standard-Model Extension provides a framework to systematically investigate possible violation of the Lorentz symmetry. Concerning gravity, the linearized version was extensively examined. We here cast the first set of experimental bounds on the nonlinear terms in the field equation from the anisotropic cubic curvature couplings. These terms introduce body-dependent accelerations for self-gravitating objects, thus violating the gravitational weak equivalence principle (GWEP). Novel phenomena, that are absent in the linearized gravity, remain experimentally unexplored. We constrain them with precise binary-orbit measurements from pulsar timing, wherein the high density and large compactness of neutron stars are crucial for the test. It is the first study that seeks GWEP-violating signals in a fully anisotropic framework with Lorentz violation.
description: 7 pages, 1 figure; accepted by PRD
Solitons and Black Holes
Creators: name: Gegenberg, J.
name: Kunstatter, G.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: We explore the relationship between black holes in Jackiw-Teitelboim(JT) dilaton gravity and solitons in sine-Gordon field theory. Our analysis expands on the well known connection between solutions of the sine-Gordon equation and constant curvature metrics. In particular, we show that solutions to the dilaton field equations for a given metric in JT theory also solve the sine-Gordon equation linearized about the corresponding soliton. Since the dilaton generates Killing vectors of the constant curvature metric, it is interesting that it has an analoguous interpretation in terms of symmetries of the soliton solution. We also show that from the B${\ddot a}$cklund transformations relating different soliton solutions, it is possible to construct a flat SL(2,R) connection which forms the basis for the gauge theory formulation of JT dilaton gravity.
description: Substantial revisions in sections 4-5, Latex file, 13 pages. Typographical errors corrected; accepted for publication in Phys. Lett. B
Phase space classification of an Ising Cellular Automaton: the Q2R model
Creators: name: Montalva-Medel, Marco
name: Rica, Sergio
name: Urbina, Felipe
Publisher: name: arXiv
Year: 2019
Subjects: subject: Cellular Automata and Lattice Gases (nlin.CG)
subject: FOS: Physical sciences

description: An exact characterization of the different dynamical behavior that exhibit the space phase of a reversible and conservative cellular automaton, the so called Q2R model, is shown in this paper. Q2R is a cellular automaton which is a dynamical variation of the Ising model in statistical physics and whose space of configurations grows exponentially with the system size. As a consequence of the intrinsic reversibility of the model, the phase space is composed only by configurations that belong to a fixed point or a limit cycle. In this work we classify them in four types accordingly to well differentiated topological characteristics. Three of them, which we call of type S-I, S-II and S-III, share a symmetry property, while the fourth, which we call of type AS, does not. Specifically, we prove that any configuration of Q2R belongs to one of the four previous limit cycles. Moreover, at a combinatorial level, we are able to determine the number of limit cycles for some small periods which are almost always present in the Q2R. Finally, we provide a general overview of the resulting decomposition of the arbitrary size Q2R phase space, in addition, we realize an exhaustive study of a small Ising system 4x4 which is fully analyzed under this new framework.
Drosophila hystricosa Hardy and Kaneshiro 1969
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila hystricosa

description: Drosophila hystricosa Hardy and Kaneshiro, 1969
Distribution: Endemic: Maui
Additional References: Hardy & Kaneshiro (1975b); Magnacca & O’Grady (2009); O’Grady & DeSalle (2008)
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 44, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841
An ecological audit of the regulatory requirements for surface coal mine reclamation in nine western North American jurisdictions
Creators: name: Smyth, Clint R.
name: Dearden, Philip
Publisher: name: The University of British Columbia
Year: 2009

description: The role of regulatory requirements and their impact on the design and implementation of high elevation coal mine reclamation programs was examined in nine mountainous western North American jurisdictions. This 'ecological audit' of regulatory requirements revealed that several jurisdictions are similar programatically in objectives but dissimilar substantively in regulatory provisions such as topographic modifications, revegetation, performance standards and enforcement. Information acquisition and dissemination also varied between jurisdictions. The current command-penalty model of environmental regulation results in adversarial interactions between government and industry in many of the jurisdictions and should be replaced by a formal negotiated system of regulation based on continuing research and adaptive management.
An introduction to a new space debris evolution model -- SOLEM
Creators: name: Wang, Xiao-Wei
name: Liu, Jing
Publisher: name: arXiv
Year: 2019
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: SOLEM is the first space debris long-term evolution model of China. This paper describes the principles, components and workflow of the SOLEM. The effects of different mitigation measures based on SOLEM model are analyzed and presented. The limitation of the model is pointed out and its future improvement work-plan is prospected.
description: 16 pages, 14 figures
Drosophila nigrocirrus Hardy 1965
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila nigrocirrus

description: Drosophila nigrocirrus Hardy, 1965
Distribution: Endemic: Hawaii
 Additional References: Carson & Kaneshiro (1976); Hardy & Kaneshiro (1975b); Magnacca & O’Grady (2009); O’Grady et al. (2011)
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 44, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841
Connecting Program Synthesis and Reachability: Automatic Program Repair using Test-Input Generation
Creators: name: Nguyen, ThanhVu
name: Weimer, Westley
name: Kapur, Deepak
name: Forrest, Stephanie
Publisher: name: arXiv
Year: 2019
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: We prove that certain formulations of program synthesis and reachability are equivalent. Specifically, our constructive proof shows the reductions between the template-based synthesis problem, which generates a program in a pre-specified form, and the reachability problem, which decides the reachability of a program location. This establishes a link between the two research fields and allows for the transfer of techniques and results between them. To demonstrate the equivalence, we develop a program repair prototype using reachability tools. We transform a buggy program and its required specification into a specific program containing a location reachable only when the original program can be repaired, and then apply an off-the-shelf test-input generation tool on the transformed program to find test values to reach the desired location. Those test values correspond to repairs for the original programm. Preliminary results suggest that our approach compares favorably to other repair methods.
Investigations of Nonlinear Optical Phenomenon and Dispersion in Integrated Photonic Devices
Creators: McMillan, James Flintoft
Publisher: name: Columbia University
Year: 2019
Subjects: Electrical engineering
Electromagnetism
Optics
Photonics
Optical wave guides

description: Integrated photonics is the field of shrinking and simplifying the fabrication of devices that guide and manipulate light. It not only offers to greatly lower the size and cost of systems used in optical communications it also offers a platform on which new physical phenomenon can be explored by being able to fabricate and manipulate structures on the scale of the wavelength of light. One such platform in integrated photonics is that of two-dimensional slab photonic crystals. These structures exhibit a photonic band-gap, a band of optical frequencies that are prohibited from propagating within the medium, that can be used to guide and confine light. When used to create photonic crystal waveguides these waveguides exhibit unique dispersion properties that demonstrate very low optical group velocities, so called "slow-light". This dissertation begins with the practical realization of design and fabrication of such waveguides using the silicon-on-insulator material system using conventional deep-UV photolithography fabrication techniques. It will detail and demonstrate the effect physical dimensions have on the optical transmission of these devices as well as their optical dispersion. These photonic crystal waveguides will then be used to demonstrate the enhancement of nonlinear optical phenomenon due to the slow-light phenomenon they exhibit. First spontaneous Raman scattering will be theoretically demonstrated to be enhanced by slow-light and then experimentally shown to be enhanced in a practical realization. The process of four-wave mixing will be demonstrated to be enhanced in these devices and be shown to be greatly affected by the unique optical dispersion within these structures. Additionally, we will examine the dispersion that exists in silicon nitride microring resonators and the effect it has on the use of these devices to generate optical frequency combs. This is done by leveraging the dispersion measurement methods used to characterize photonic crystal waveguides. We conclude this work by examining the avenues of future work that can be explored in the area of photonic crystal waveguides.
Capitalisation of residential solar photovoltaic systems in Western Australia
Creators: name: Ma, Chunbo
name: Polyakov, Maksym
name: Pandit, Ram
name: Ma, Chunbo
name: Polyakov, Maksym
name: Pandit, Ram
Publisher: name: Unknown
Year: 2015
Subjects: subject: Demand and Price Analysis
subject: Environmental Economics and Policy
subject: Australia
subject: hedonic
subject: photovoltaic
subject: repeated sales
subject: solar panels

description: Due to government financial incentives and falling prices of photovoltaic (PV) systems, solar power has become the fastest growing renewable energy source in Australia. As financial incentives are being reduced or phased out, there is a possibility that adoption of this technology will slow down, thus creating a need for improved policy instruments targeted at adoption of residential PV systems. One of the factors affecting adoption of solar technology in the residential sector is its capitalisation in property values. Yet, the awareness of the capitalisation of PV investments in the Australian property market is limited. Our data indicate that homeowners who anticipate selling their properties in the near future are reluctant to adopt PV systems. This paper presents the first empirical estimate of the property price premiums associated with residential solar PV systems in Australia using residential property sales data from the Perth metropolitan area of Western Australia. An estimated 2.3– 3.2 per cent property price premium associated with the PV systems suggests that homeowners fully recover the costs of PV investments upon the sale of their properties. Effective government policy could use this information to encourage adoption of residential PV systems by homeowners.
The quantum inequalities do not forbid spacetime shortcuts
Creators: name: Krasnikov, S.
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: A class of spacetimes (comprising the Alcubierre bubble, Krasnikov tube, and a certain type of wormholes) is considered that admits `superluminal travel' in a strictly defined sense. Such spacetimes (they are called `shortcuts' in this paper) were suspected to be impossible because calculations based on `quantum inequalities' suggest that their existence would involve Planck-scale energy densities and hence unphysically large values of the `total amount of negative energy' E_tot. I argue that the spacetimes of this type may not be unphysical at all. By explicit examples I prove that: 1) the relevant quantum inequality does not (always) imply large energy densities; 2) large densities may not lead to large values of E_tot; 3) large E_tot, being physically meaningless in some relevant situations, does not necessarily exclude shortcuts.
description: Minor corrections and additions
Drosophila oroscopa Magnacca and O'Grady 2009
Creators: name: Rampasso, Augusto Santos
name: O'Grady, Patrick Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Psathyrellaceae
Drosophila
Drosophila oroscopa

description: Drosophila oroscopa Magnacca and O’Grady, 2009
Distribution: Endemic: Hawaii
description: Published as part of Rampasso, Augusto Santos & O'Grady, Patrick Michael, 2022, Distribution and Taxonomy of Endemic and Introduced Drosophilidae in Hawaii, pp. 1-80 in Zootaxa 5106 (1) on page 39, DOI: 10.11646/zootaxa.5106.1.1, http://zenodo.org/record/6336841
Generalised polynomials and integer powers
Creators: name: Konieczny, Jakub
Publisher: name: arXiv
Year: 2019
Subjects: subject: Number Theory (math.NT)
subject: Combinatorics (math.CO)
subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: We show that there does not exist a generalised polynomial which vanishes precisely on the set of powers of two. In fact, if $k \geq 2$ is and integer and $g \colon \mathbb{N} \to \mathbb{R}$ is a generalised polynomial such that $g(k^n) = 0$ for all $n \geq 0$ then there exists infinitely many $m \in \mathbb{N}$, not divisible by $k$, such that $g(mk^n) = 0$ for some $n \geq 0$. As a consequence, we obtain a complete characterisation of sequences which are simultaneously automatic and generalised polynomial.
description: 51 pages
Agriculture, trade openness and emissions: an empirical analysis and policy options
Creators: name: Rafiq, Shuddhasattwa
name: Salim, Ruhul
name: Apergis, Nicholas
name: Rafiq, Shuddhasattwa
name: Salim, Ruhul
name: Apergis, Nicholas
Publisher: name: Unknown
Year: 2015
Subjects: subject: Agribusiness
subject: International Relations/Trade
subject: agricultural value added
subject: carbon dioxide emissions
subject: dynamic heterogeneous panels
subject: nonlinear panel estimation under cross-sectional dependence
subject: trade openness

description: This article investigates the impact of sectoral production allocation, energy usage patterns and trade openness on pollutant emissions in a panel consisting of high-, medium- and low-income countries. Extended STIRPAT (Stochastic Impact by Regression on Population, Affluence and Technology) and EKC (Environmental Kuznets Curve) models are conducted to systematically identify these factors driving CO2 emissions in these countries during the period 1980–2010. To this end, the study employs three different heterogeneous, dynamic mean group-type linear panel models and one nonlinear panel data estimation procedure that allows for cross-sectional dependence. While affluence, nonrenewable energy consumption and energy intensity variables are found to drive pollutant emissions in linear models, population is also found to be a significant driver in the nonlinear model. Both service sector and agricultural value-added levels play a significant role in reducing pollution levels, whereas industrialisation increases pollution levels. Although the linear model fails to track any significant impact of trade openness, the nonlinear model finds trade liberalisation to significantly affect emission reduction levels. All of these results suggest that economic development, and especially industrialisation strategies and environmental policies, need to be coordinated to play a greater role in emission reduction due to trade liberalisation.
Noise and slow-fast dynamics in a three-wave resonance problem
Creators: name: Lythe, G. D.
name: Proctor, M. R. E.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Recent research on the dynamics of certain fluid dynamical instabilities shows that when there is a slow invariant manifold subject to fast timescale instability the dynamics are extremely sensitive to noise. The behaviour of such systems can be described in terms of a one-dimensional map, and previous work has shown how the effect of noise can be modelled by a simple adjustment to the map. Here we undertake an in depth investigation of a particular set of equations, using the methods of stochastic integration. We confirm the prediction of the earlier studies that the noise becomes important when mu|log(epsilon)| = O(1), where mu is the small timescale ratio and εis the noise level. In addition, we present detailed information about the statistics of the solution when the noise is a dominant effect; the analytical results show excellent agreement with numerical simulations.
description: Plain TeX, 12 pages, 4 postscript figures included