cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Ð¤ÑÐ½ÐºÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð½Ð°Ð¸Ð¼ÐµÐ½Ð¾Ð²Ð°Ð½Ð¸Ð¹ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÑ Ð² ÑÐ»ÐµÐ½Ð³Ðµ Ð°Ð½Ð³Ð»Ð¸Ð¹ÑÐºÐ¾Ð³Ð¾ ÑÐ·ÑÐºÐ°
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÑÑÐµÐ¹Ð½Ð¾Ð²Ð°, ÐÑÐºÐ¸Ð½Ð°Ð·
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÑÐ»ÐµÐ½Ð³
Ð·Ð¾Ð¾Ð½Ð¸Ð¼Ñ
Ð½Ð°Ð¸Ð¼ÐµÐ½Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÑ

description: Ð ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð¼ Ð¼Ð¸ÑÐµ Ð¿Ð¾Ð¿ÑÐ»ÑÑÐ½Ð¾ÑÑÑ ÑÐ»ÐµÐ½Ð³Ð¾Ð²ÑÑ Ð²ÑÑÐ°Ð¶ÐµÐ½Ð¸Ð¹ Ð¿Ð¾ÑÑÐ¾ÑÐ½Ð½Ð¾ ÑÐ°ÑÑÑÑ. ÐÑÐ¾Ð±ÑÐ¹ Ð¸Ð½ÑÐµÑÐµÑ Ð² ÑÑÐ¾Ð¼ Ð¾ÑÐ½Ð¾ÑÐµÐ½Ð¸Ð¸ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÑÑÑ ÑÐ»ÐµÐ½Ð³Ð¾Ð²ÑÐµ Ð²ÑÑÐ°Ð¶ÐµÐ½Ð¸Ñ, ÑÐ¾ÑÑÐ°Ð²Ð½ÑÐ¼Ð¸ ÑÐ°ÑÑÑÐ¼Ð¸ ÐºÐ¾ÑÐ¾ÑÑÑ ÑÐ²Ð»ÑÑÑÑÑ Ð½Ð°Ð·Ð²Ð°Ð½Ð¸Ñ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÑ Ð¸ ÑÐ¿Ð¾ÑÐ¾Ð±Ñ Ð¸Ñ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð² ÑÐ»ÐµÐ½Ð³Ðµ. Ð Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð¾Ð±Ð·Ð¾Ñ ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð°ÑÐ¿ÐµÐºÑÐ¾Ð² Ð¸Ð·ÑÑÐµÐ½Ð¸Ñ ÑÐ»ÐµÐ½Ð³Ð° Ð¸ ÐµÐ³Ð¾ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐµÐ¹ Ð² ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð¹ Ð»Ð¸Ð½Ð³Ð²Ð¸ÑÑÐ¸ÐºÐµ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÑÑÐ´Ð¾Ð² Ð¸Ð·Ð²ÐµÑÑÐ½ÑÑ Ð»Ð¸Ð½Ð³Ð²Ð¸ÑÑÐ¾Ð². Ð Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ñ Ð±Ð°Ð·Ð¾Ð²ÑÐµ ÐºÐ°ÑÐµÐ³Ð¾ÑÐ¸Ð¸ Ð»Ð¸Ð½Ð³Ð²Ð¸ÑÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð·Ð½Ð°Ð½Ð¸Ñ Ð¾ Ð¿ÑÐ¾ÑÑÑÐ°Ð½ÑÑÐ²Ðµ ÐºÐ°Ðº ÑÐ¿Ð¾ÑÐ¾Ð±Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð´ÐµÐ¹ÑÑÐ²Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐ¸ÑÐ¾ÐºÐ¾ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·ÑÑÑÑÑ Ð² ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÑ Ð»Ð¸Ð½Ð³Ð²Ð¸ÑÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸ÑÑ. Ð Ð¿ÑÐ¾ÑÐµÑÑÐµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¾ÑÐ¾Ð±ÑÐ°Ð½Ð¾ Ð¸ Ð¿ÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð¾ 250 ÑÐ»ÐµÐ½Ð³Ð¾Ð²ÑÑ ÐµÐ´Ð¸Ð½Ð¸Ñ, Ð¸Ð¼ÐµÑÑÐ¸Ñ Ð² ÑÐ²Ð¾ÐµÐ¼ ÑÐ¾ÑÑÐ°Ð²Ðµ ÑÐ¾Ð±ÑÑÐ²ÐµÐ½Ð½Ð¾ Ð·Ð¾Ð¾Ð½Ð¸Ð¼Ñ (Ð½Ð¾Ð¼Ð¸Ð½Ð°ÑÐ¸Ð¸ Ð´Ð¸ÐºÐ¸Ñ Ð¸ Ð´Ð¾Ð¼Ð°ÑÐ½Ð¸Ñ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÑ). ÐÐ° Ð¿ÑÐ¾ÑÑÐ¶ÐµÐ½Ð¸Ð¸ Ð²ÑÐµÐ³Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¿ÑÐ¸Ð²Ð¾Ð´Ð¸ÑÑÑ Ð¼ÑÑÐ»Ñ Ð¾ ÑÐ¾Ð¼, ÑÑÐ¾ ÑÐ»ÐµÐ½Ð³Ð¾Ð²ÑÐµ Ð²ÑÑÐ°Ð¶ÐµÐ½Ð¸Ñ, Ð²ÐºÐ»ÑÑÐ°ÑÑÐ¸Ðµ Ð½Ð°Ð¸Ð¼ÐµÐ½Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÑ, Ð¿ÑÐ¸Ð´Ð°ÑÑ ÑÐºÑÐ¿ÑÐµÑÑÐ¸Ð²Ð½Ð¾ÑÑÑ ÑÐµÑÐ¸, Ð¿ÑÐ¸ ÑÑÐ¾Ð¼ ÑÐ°Ð¼Ð¸ Ð¾Ð±ÑÐ°Ð·Ñ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÑ Ð´ÐµÐ»Ð°ÑÑ ÑÐ»ÐµÐ½Ð³ Ð±Ð¾Ð»ÐµÐµ Ð¶Ð¸Ð²ÑÐ¼ Ð¸ Ð·ÑÐ¸Ð¼ÑÐ¼, Ð¿ÑÐ¸Ð´Ð°Ð²Ð°Ñ ÑÑÐ°Ð·Ð°Ð¼ Ð¼ÐµÑÐ°ÑÐ¾ÑÐ¸ÑÐ½Ð¾ÑÑÑ.
Gene therapy for improving peripheral nerve regeneration and preventing muscle atrophy after nerve trauma
Creators: name: Raimondo, Stefania
name: Ronchi, Giulia
name: Fregnan, Federica
name: Robecchi, Maria-Giuseppina
name: Geuna, Stefano
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014

description: Skeletal muscle atrophy following denervation may not allow a good functional recovery if the muscle is not quickly re-innervated by the regenerating nerve fibers. In this regard, both improvement of peripheral nerve regeneration and prevention of skeletal muscle atrophy are important to achieve a satisfactory functional recovery after nerve injury. Local gene transfer could represent a promising strategyto reach this goal. Various genes are candidates in fostering peripheral axon regeneration and in preventing muscle atrophy, among these, the vascular endothelial growth factor (VEGF). The main goals of our study were twofold: (i) to accelerate axonal regeneration along muscle-vein-combined conduits used to bridge a 1-cm-long rat median nerve gap, and (ii) to prevent denervation-related atrophy of Fingers Flexor muscle after complete rat median nerve transection. Results showed that the over-expression of VEGF led to a worse nerve regeneration in the muscle-vein-combined guide in comparison to LacZ controls, whereas in the muscle it led to a significantly lower progression of atrophy. Altogether, our results suggest that VEGF direct local injection in denervated skeletal muscle significantly attenuates denervation-related atrophy thus representing a promising strategy for improving the outcome of posttraumatic neuromuscular recovery after nerve injury and repair.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
The Prospects for Peace in Cyprus: The Impact of Elections in the North
Creators: name: Dizdaroglu, Cihan
Publisher: name: Zenodo
Year: 2020
Subjects: Cyprus
Elections
Peace
Youth
Peace Negotiations
Northern Cyprus
Eastern Mediterranean
Energy

description: Turkish Cypriots are preparing to elect their fifth president – the next community leader – to guide the peace negotiations. The presidential election in the Turkish Republic of Northern Cyprus (TRNC), originally scheduled for 26 April, was postponed due to the coronavirus pandemic and will soon be held on 11 October 2020. In this policy paper, Dr. Cihan Dizdaroğlu discusses the extent to which the election affects the prospects for a solution in Cyprus
The understanding of the anatomy and functional role of the valves of the veins and its impact on hemodynamics
Creators: name: Riva, A.
name: Loy, F.
name: Isola, R.
name: Isola, M.
name: Conti, G.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014
Subjects: Valve of the vein; Fabricius; Harvey; Riva-Rocci

description: Although the valves of veins were reported by some anatomists years before Fabricius ab Aquapendente (1533-1619) held his public demonstration in 1579, the first detailed description of these structures is ascribed to him, who in 1602 published the “De Venarum Ostiolis” (1). Fabricius held the chair of Anatomy in Padua for over 50 years and in the course of his long and prestigious academic career had many illustrious pupils among which there was William Harvey the future discoverer of the circulation of blood (2). Fabricius who also was a celebrated surgeon, gave important contributions in various fields of human and comparative anatomy and embryology. Concerning the valves of veins he stated, erroneously that they were little doors (ostioli) having the function of slowing the flow of blood which, according to Galen was directed away from the heart. In spite of this, it were just the “valves in the veins” that induced Harvey to think of a circulation of the blood (3). The valves functional role, in pathology as well, was clarified in the “De Motu” by a series of experiments, carried out in different animal species that proved the centripetal course of venous blood. By the same model illustrated by Fabricius and reproduced even in the “De Motu”, Harvey demonstrated that a mild ligature of the human arm interrupts just the venous flow, whereas a tighter one blocks the arteries, with reversible loss of pulsation that returns upon removal of the stricture. In the centuries that followed, this last observation became instrumental in the understanding of the laws of hemodynamics and, also on the development of non invasive methods for measurement of blood pressure.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
title: Using Graphic Organizers with Scriptural Text: Ninth-Grade Latter-Day Saint (LDS) Students’ Comprehension of Doctrinal Readings and Concepts
Creators: name: Potter, Mark D.
Publisher: name: Utah State University
Year: 2011

description: This study investigated the effect of instruction that included graphic organizers on LDS seminary students’ ability to understand scriptural text and their ability to identify doctrines in scriptural text, utilizing a repeated measures, quasi-experimental design involving 209 ninth-grade student participants. The participants were randomly assigned by class to one of two treatment groups. Participants in the treatment group received instruction using graphic organizers with the standard curriculum and participants in the comparison group received instruction using only the standard curriculum. Three different measures were employed to measure the effectiveness of the graphic organizers intervention: (a) a multiple-choice test of LDS doctrines and principles; (b) an identifying doctrines and principles in text test; and (c) a student perception survey. Results of the ANOVA for the multiple-choice test indicated no significant difference between instructional groups for ability to recall facts from the class instruction and the class text, F (1, 205) = 1.60, p = .21, partial ή² = .21. Results of the ANOVA for the identifying doctrines and principles in text test, measuring transferability of the skills learned while studying the Doctrine and Covenants to a different text containing some of the same doctrines and principles, also indicated no significant difference between groups, F (1, 196) = 1.93, p = .17. The results for the student perception survey were positive; most students felt confident about their ability to comprehend scriptural text, but were slightly less confident about their ability to identify doctrines and principles in the text. The participants in this study were generally positive in their willingness to learn about and use graphic organizers. Results of this study indicated that graphic organizers did not significantly impact students’ ability to identify doctrines and principles in scriptural text or to learn concepts from scriptural text.
Additional file 2 of Lost genome segments associate with trait diversity during rice domestication
Creators: name: Zheng, Xiaoming
name: Zhong, Limei
name: Pang, Hongbo
name: Wen, Siyu
name: Li, Fei
name: Lou, Danjing
name: Ge, Jinyue
name: Fan, Weiya
name: Wang, Tianyi
name: Han, Zhenyun
name: Qiao, Weihua
name: Pan, Xiaowu
name: Zhu, Yebao
name: Wang, Jilin
name: Tang, Cuifeng
name: Wang, Xinhua
name: Zhang, Jing
name: Xu, Zhijian
name: Kim, Sung Ryul
name: Kohli, Ajay
name: Ye, Guoyou
name: Olsen, Kenneth M.
name: Fang, Wei
name: Yang, Qingwen
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology

description: Additional file 2: Table S1. The results of 80 cultivated and wild rice genomes survey. Table S2. Summary of Nanopore Technologies sequencing data of JX1 and SL1 genome. Table S3. Summary of sequencing assembly data of JX1 and SL1 genome. Table S4. Details of the 12 pseudo-chromosomes of JX1 and SL1. Table S5. Summary of sequencing evaluation data of JX1 and SL1genome. Table S6. Repetitive elements in JX1 and SL1 genomes. Table S7. The information of full length transcriptome sequencing data of JX1 and SL1. Table S8. The transcriptome sequencing data from different tissues of JX1 and SL1 based on Illumina sequence. Table S9. Annotated predictions of gene structure. Table S10. Summary of the assembly of 13 cultivated and wild rice genomes. Table S11. The SV information for 13 cultivated and wild rice. Table S12. Sequence information for structural variation. Table S13. The annotation of SV. Table S14. The sample list for SV population analysis. Table S15. The significant association sites based on GWAS data. Table S16. 49 cloned genes overlapping with DELs (>10 kb) region.
Transition to sub-Planck structures through the superposition of q-oscillator stationary states
Creators: name: Jafarov, E. I.
name: Van der Jeugt, J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 81P40, 81Q80, 33D45, 81S30

description: We investigate the superposition of four different quantum states based on the $q$-oscillator. These quantum states are expressed by means of Rogers-Szegö polynomials. We show that such a superposition has the properties of the quantum harmonic oscillator when $q\to 1$, and those of a compass state with the appearance of chessboard-type interference patterns when $q \to 0$.
description: 5 pages, 6 eps files
3D culture of multipotent cells derived from waste human ovarian follicular liquid and seeded onto gelatin cryogel
Creators: name: Riva, Federica
name: Omes, Claudia
name: Fassina, Lorenzo
name: Vaghi, Patrizia
name: Reguzzoni, Marcella
name: Casasco, Marco
name: Icaro Cornaglia, Antonia
name: Casasco, Andrea
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014
Subjects: Mesenchymal Stem Cells; Waste Human Ovarian Follicular Liquid; Gelatin Cryogel Scaffold; Proliferation and Differentiation; Immunostaining Analysis; Confocal Microscopy and Scanning Electron Microscopy Analysis

description: Current tissue engineering uses 3D biomaterials in combination with stem cells, since mature cells are often not available in sufficient amounts or quality. Biomaterial scaffolds have been widely used in reconstructive bone surgery not only as cell carriers providing mechanical support, but also as promoters of cell attachment and proliferation (1). In particular, gelatine cryogel scaffolds are promising new biomaterials owing to their biocompatibility and to substain the differentiation of mesenchymal stromal stem cells (MSCs) (2). Human MSC proliferate onto the surfaces with fibroblastic morphology and can differentiate into osteoblasts, chondrocytes and adipocytes (3). These cells can be isolated from several sources, including bone marrow and adipose tissue (4). Our previously studies showed the possibility to obtain MSCs also from the human ovarian follicular liquid (FL) that is usually wasted during in vitro fertilization (5). In this study, we tested the ability of these FL cells to grow and differentiate on gelatine cryogel in comparison with MSCs derived from human bone marrow. Samples and controls were analyzed with confocal and scanning electron microscopes. Results demonstrated that FL cells could grow on the biomaterial not only on the top but also in the layers below till 60mm of deepness. Data suggested that the observed cells are mesenchymal since positive for vimentin and CD44 (a typical MSC marker). Preliminary results showed also the capability of induced FL cells to osteogenic differentiation to produce bone extracellular matrix, expressing some specific proteins (i.e.osteopontin). In conclusion, MSCs derived from waste human ovarian follicular liquid showed promising affinity with 3D gelatine cryogel, opening new potential developments in biotech and medical applications.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
D2.1.2 – Second workshop held & report on recommendations of 2nd workshop
Creators: name: University of Surrey
Publisher: name: Zenodo
Year: 2005
Subjects: NoE and NEXUS Projects
The EuroFIR Food Platform
EuroFIR

description: Executive SummaryThis report summarizes results from the second interactive workshop with key food composition data users. A 50-minute workshop was held at the 6th National Nutrition & Health conference on 26th November in London. The audience was composed of Nutritionists and Dieticians working in the public health and food industry sector. This workshop forms part of a planned series of workshops in different countries with different audiences. These workshops are part of a comprehensive plan of various activities for WP2.1, which has the overall aim to enter into a dialogue with all user and stakeholder groups in order to ensure that user and stakeholder requirements are established and considered in the process of building sustainable and durable food databank systems.
title: ÐÑÐ½Ð¾Ð²Ñ ÑÐµÐ¾ÑÐ¸Ð¸ ÑÐµÐ·Ð°Ð½Ð¸Ñ Ð¼ÐµÑÐ°Ð»Ð»Ð¾Ð²
Creators: name: ÐÐ¾Ð±ÑÐ¾Ð², ÐÑÐµÐ²Ð¾Ð»Ð¾Ð´
Publisher: name: ÐÐ°ÑÐ¸Ð½Ð¾ÑÑÑÐ¾ÐµÐ½Ð¸Ðµ
Year: 1975
Subjects: Ð ÐµÐ·Ð°Ð½Ð¸Ðµ Ð¼ÐµÑÐ°Ð»Ð»Ð¾Ð²

description: Ð ÐºÐ½Ð¸Ð³Ðµ Ð¾ÑÐ²ÐµÑÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð²Ð¾Ð¿ÑÐ¾ÑÑ Ð¿ÑÐ¾ÑÐµÑÑÐ° ÑÐµÐ·Ð°Ð½Ð¸Ñ Ð¼ÐµÑÐ°Ð»Ð»Ð¾Ð² Ð¸ ÑÑÐ»Ð¾Ð²Ð¸Ð¹ ÑÐ°ÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ð¹ ÑÐºÑÐ¿Ð»ÑÐ°ÑÐ°ÑÐ¸Ð¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ¾Ð², ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð³ÐµÐ¾Ð¼ÐµÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ¾Ð² ÑÑÐ°ÑÐ¸ÐºÐµ Ð¸ Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ð¸, ÑÐ¾ÑÐ¼Ð° Ð¸ ÑÐ°Ð·Ð¼ÐµÑÑ ÑÑÐµÐ·Ð°ÐµÐ¼Ð¾Ð³Ð¾ ÑÐ»Ð¾Ñ Ð¿ÑÐ¸ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð²Ð¸Ð´Ð°Ñ ÑÐ°Ð±Ð¾Ñ, Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ñ Ð¾ÑÂ­Ð½Ð¾Ð²Ð½ÑÐµ Ð·Ð°ÐºÐ¾Ð½Ð¾Ð¼ÐµÑÐ½Ð¾ÑÑÐ¸ Ð¿ÑÐµÐ²ÑÐ°ÑÐµÐ½Ð¸Ñ ÑÑÐµÐ·Ð°ÐµÐ¼Ð¾Ð³Ð¾ ÑÐ»Ð¾Ñ Ð² ÑÑÑÑÐ¶ÐºÑ ÑÐ¾ Ð²ÑÐµÐ¼Ð¸ ÑÐ¾Ð¿ÑÑÑÑÐ²ÑÑÑÐ¸Ð¼Ð¸ ÐµÐ¼Ñ ÑÐ²Ð»ÐµÐ½Ð¸ÑÐ¼Ð¸, ÑÐ¸Ð»Ð¾Ð²ÑÐµ Ð¸ ÑÑÐ¾Ð¹ÐºÐ¾ÑÑÐ½ÑÐµ Ð·Ð°Ð²Ð¸ÑÐ¸Â­Ð¼Ð¾ÑÑÐ¸ Ð¿ÑÐ¸ ÑÐºÑÐ¿Ð»ÑÐ°ÑÐ°ÑÐ¸Ð¸ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ¾Ð². ÐÐ°Ð½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ Ð²ÑÐ±Ð¾ÑÑ ÑÐ°ÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ð³Ð¾ ÑÐµÐ¶Ð¸Ð¼Ð° ÑÐµÐ·Ð°Ð½Ð¸Ñ. ÐÐ½Ð¸Ð³Ð° Ð¿ÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð° Ð´Ð»Ñ Ð¸Ð½Ð¶ÐµÐ½ÐµÑÐ½Ð¾-ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ°Ð±Ð¾ÑÐ½Ð¸ÐºÐ¾Ð² Ð¼ÐµÑÐ°Ð»Ð»Ð¾Ð¾Ð±ÑÐ°Ð±Ð°ÑÑÐ²Ð°ÑÑÐµÐ¹ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½Ð¾ÑÑÐ¸.
title: When They Called Us Jie Mei (Sister) An Autoethnographic and Narrative Study of Religious Development in Emerging Adulthood
Creators: name: Ball, Katie Nichole
Publisher: name: Utah State University
Year: 2011

description: The years from the late teens through the twenties increasingly have become an important area of study. The age range between 18 and 25 makes up a new, distinct developmental period that is referred to as “emerging adulthood.” Recent work has suggested that individuals engage in their most extensive identity exploration during emerging adulthood. This study uses autoethnography and narrative biographical material to study emerging adulthood in the contexts of spiritual and personal growth. The study explored adult development among young women serving abroad as missionaries for The Church of Jesus Christ of Latter-day Saints (LDS). The sample consisted of five women, including myself, all of whom shared similar background characteristics and served in the same mission. Interviews were conducted in which participants gave a unique description of their LDS mission experiences while responding to open-ended questions. Data analysis was done by gathering participants’ stories and then “restory (ing)” them into a framework that made sense. Stories presented here were based on the primary themes identified in participant interviews and my own experiences. These themes included: it was the right decision to serve a mission, development happened through experiencing adversity and through positive experiences, the mission lifestyle either helped or deterred participants’ growth and development, and the participants are who they are today because of this experience. Future longitudinal research could focus on how a mission has affected women’s lives throughout adulthood, or on the relationship between exposure to other cultures and individual psychosocial development.
title: Investigating surface acoustic waves and fluorescence techniques for lab-on-a-chip diagnostics
Creators: name: Orgill, Jonathan
Publisher: name: University of Glasgow
Year: 2021
Subjects: subject: Surface Acoustic Waves, DNA, melting, annealing, fluorescence, quenching of fluorophores, PCR, LAMP, FRET, TIRF, microfluidics.

description: There is an emerging need for low-cost medical diagnostics for both high and middle to low-resource settings. Surface acoustic waves microfluidics are emerging lab-on-a-chip technologies which have the potential to provide all-in-one solution to actuate liquids and sense biomarkers, thus enabling point-of-care bioassays. DNA has become a key biomarker for a range of medical conditions, including infectious diseases, as it provides critical information on the pathogen or the response of the patients to particular treatment, on a personalized basis. This thesis will examine the effects of surface acoustic waves on DNA hybridization, with a view to integrate molecular diagnostic assays onto acousto-fluidic devices. The work used fluorescence to characterize the binding of DNA in a range of conditions, and revealed nucleobase-specific quenching (NB-S Quench) of fluorophores when attached to DNA as a double strand. This latter effect was examined as a replacement for common analytical markers used in standard techniques, such as melting curves, which typically rely on dyes which recognize DNA strands non-specifically (such as groove binders). The technique has been shown to be suitable for determine the concentration of DNA, performing DNA amplification and identifying the presence and melting temperature of target DNA. This work will have an impact on research into low-cost medical diagnostics, and improve the understanding of fluorescence of DNA modified with fluorophores, contributing to the understanding of future work in these areas.
The influence of mechanogastric distension via autonomic nerve on hemodynamic outputs
Creators: name: Sabbatini, Maurizio
name: Grossini, Elena
name: Vacca, Giovanni
name: Cannas, Mario
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014
Subjects: gastric distension; blood pressure; mechanogastric reflex; vagus nerve; splachnich nerve; functional hindbrain nuclei mapping

description: The meal presence of carbohydrate, particularly glucose performs a loading of intraduodenal glucose that elicits blood pressure fall; but the gastric distension cooperate counterbalancing this visceral reflex slightly increasing heart rate and blood pressure mainly via orthosympathetic nerves. However in the elderly and in patients with autonomic dysfunction postprandial hypothension, became an important clinical problem [1]. We have previously observed that several hindbrain nuclei are involved in cardiovascular reflexes elicited by mechanogastric dilatation in which vagal parasympathetic and splanchnic sympathetic component participate to define their responses [2,3]. Therefore in the present work monolateral and bilateral vagotomy and splanchnotomy have been performed to assert the involvement of visceral nervous system hindbrain nuclei in hemodynamic control following gastric mechanical dilatation at high and low pressure. The mapping of c-Fos positive neurons have shown the occurrence of cooperative pathways between vagal and splanchnic component in several nuclei under analysis, similarly an integrated response between controlateral areas of single nuclei has been observed. In particular following mechanogastric experimental protocols adopted, the physiological response on blood pressure and heart rate, shows a preponderance effect of orthosympathetic component, but its plain functional expression need of parasympathetic component involvement.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
Additional file 1 of Lost genome segments associate with trait diversity during rice domestication
Creators: name: Zheng, Xiaoming
name: Zhong, Limei
name: Pang, Hongbo
name: Wen, Siyu
name: Li, Fei
name: Lou, Danjing
name: Ge, Jinyue
name: Fan, Weiya
name: Wang, Tianyi
name: Han, Zhenyun
name: Qiao, Weihua
name: Pan, Xiaowu
name: Zhu, Yebao
name: Wang, Jilin
name: Tang, Cuifeng
name: Wang, Xinhua
name: Zhang, Jing
name: Xu, Zhijian
name: Kim, Sung Ryul
name: Kohli, Ajay
name: Ye, Guoyou
name: Olsen, Kenneth M.
name: Fang, Wei
name: Yang, Qingwen
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology

description: Additional file 1: Fig. S1. (a) Geographic origins of cultivated and wild rice accessions in this study. (b) SNP-based phylogenetic tree based on short-read sequencing of more than 600 cultivated and wild rice accessions. Major taxonomic groups are marked by colored lines along the circumference. Colored dots indicate a subset of the 80 accessions selected for genome survey. Fig. S2. Chromosome karyotyping of JX1 (a) and SL1 (b) in meiosis period in the root tip. Fig. S3. Distribution of short reads mapped on corresponding genome assemblies. (a) is JX1 and (b) is SL1. Fig. S4. Dot plots of assembly comparisons between JX1 and Nipponbare (a) and between SL1 and Nipponbare (b). Fig. S5. Relationship between SVs and their surrounding genes. Fig. S6. Venn-like diagram presenting the numbers of SVs among indica, japonica, and wild rice. Fig. S7. For each SV, the distance to the telomeric (a) and centromeric regions (b) of each chromosome was calculated and divided into 100-kb bins. (c) SV densities of short/long chromosome arms in continuous 200-kb windows. Significance was tested by Fisher’s exact test; NA indicates p > 0.05. Fig. S8. PCA plots of cultivated and wild rice accessions based on SV diversities. The three subgroups are indicated in different colors at the top of the Fig. Fig. S9. Phenotypes of the rice population used for GWAS, include FLL (flag leaf length), FLW (flag leaf width), GL (grain length), GW (grain width), PB (primary branch), PH (plant height), SB (secondary branch), and TGW (1000 grain weight). Fig. S10. GWASs on FLL, FLW, GL, GW, PB, PH, SB, and TGW using the compressed MLM. Manhattan plots for these phenotypes. The log10-transformed P values from a genome-wide scan were plotted against the position on each of the 12 chromosomes. Quantile-quantile plot for these phenotypes. The horizontal axis shows log10-transformed expected P values, and the vertical axis indicates log10-transformed observed P values. Fig. S11. (a) XP-CLR scores calculated by SNPs comparing wild rice with cultivated rice. (b) XP-CLR scores calculated by SVs comparing wild rice with cultivated rice. Chromosomes are painted with either blue or orange and the black line is defined using the top 5% XP-CLR scores.
Effects of a new nanocomposite system on Human Gingival Fibroblasts/Streptococcus mitis co-culture
Creators: name: Sancilio, Silvia
name: Di Giacomo, Viviana
name: Pacella, Stephanie
name: Di Bartolomeo, Soraya
name: Travan, Andrea
name: Marsich, Eleonora
name: Cataldi, Amelia
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014
Subjects: BisGMA/TEGDMA; co-culture; saliva; silver coated thermosets; cytotoxicity

description: In the broad field of biomaterials, Bisphenol A glycidylmethacrylate (BisGMA)/triethyleneglycol dimethacrylate (TEGDMA) thermosets are frequently used for dental restoration (Lehtinen et al 2008), but infections due to bacterial adhesion remain the main reason of dental devices failure. In order to avoid biofilm formation on the components used for restoration and to reduce cytotoxicity against eukaryotic cells, a new material with antimicrobial properties was developed. Indeed, silver nanoparticles (n-Ag), which have well-known antimicrobial properties, were stabilized with a polyelectrolyte solution-Chitlac (lactose-modified chitosan) and was used to coating methacrylic thermosets (Travan et al, 2011). This study was aimed at evaluating the in vitro biological response of human gingival fibroblasts (HGFs)/Streptococcus mitis co-colture to this nanocomposite system. HGFs were obtained from fragments of healthy marginal gingival tissue, co-cultured with the clinical strain of S. mitis and treated for 24 -48 h with thermosets (uncoated or coated with Chitlac or Chitlac n-Ag). Cytotoxicity was evaluated by LDH assay; cell morphology and adhesion were verified by means of SEM and optical microscopy; cell migration was studied by a modified Boyden chamber and finally IL-6 and PGE2 secretion were detected by ELISA assays. In vitro results showed that in our co-culture model, which mimics the microenvironment of the oral cavity, the nanocomposite material does not exert cytotoxic effect towards HGFs that are able to adhere and migrate. The secretion of IL-6 is significant, but PGE2 production is minimal suggesting that IL-6 production is not related to an inflammatory response. Basing on its good biocompatibility we suggest this new tool useful for the realization of dental devices.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
title: ÐÐ»Ð¸ÑÐ½Ð¸Ðµ ÑÐºÑÐ¿Ð¾ÑÑÐ½Ð¾Ð³Ð¾ Ð¿Ð¾ÑÐµÐ½ÑÐ¸Ð°Ð»Ð° Ð½Ð° Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÑ ÑÑÑÐ´Ð° (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐµÐ½Ð¸Ð½Ð³ÑÐ°Ð´ÑÐºÐ¾Ð¹ Ð¾Ð±Ð»Ð°ÑÑÐ¸)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐµÐ»Ð¾Ð²Ð°, ÐÑÐ¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð²ÑÑÐ¾ÐºÐ¾ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸ÑÐ½Ð¾Ðµ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ
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ÑÐºÑÐ¿Ð¾ÑÑÐ½ÑÐ¹ Ð¿Ð¾ÑÐµÐ½ÑÐ¸Ð°Ð»

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ ÑÑÐ´Ð¾ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÐ½ÑÐ¹ ÐºÐ»Ð°ÑÑÐµÑ.
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The relationship between lamprophyre dykes and ore deposits with special reference to British Columbia
Creators: name: Young, John W.
Publisher: name: University of British Columbia
Year: 2012

description: Some conceptions by Bowen regarding the processes apparently involved in the formation of ultra-basic lamprophyres have been applied to observations made on reaction-rims in the rocks of this thesis. An attempt has been made to find, in the reaction-rims surrounding basic minerals, phenomena that might indicate that reactions took place, during the time the rock was forming, between the basic minerals and an alkaline liquid. No conclusive evidence of such reactions was found but the suggestion is made that there is an unusually great development of reaction rims, especially in the more basic lamprophyres, that may be due to the effect of an alkaline liquid. Another theory by Bowen, dealing with the possible origin of ore-bearing solutions, has been amplified to present possible reasons for a close relation between lamprophyres and ore. On the more practical side, a petrographic study of lamprophyres and associated ore has revealed an intra-mineralization age for lamprophyres whose field relations do not conclusively indicate contemporaneity with ore. A compilation from the literature, of facts pertaining to most of the lamprophyre occurrences in British Columbia, has provided interesting statistics on the geographical and geological distribution of lamprophyres, and on their relations to different types of ore. The majority of lamprophyres occur in the Rossland-Ymir-Nelson-Slocan belt, near the eastern contact of the Nelson series of batholiths, while most of the remainder are confined to the eastern contact of the Coast Range batholith. The lamprophyres of the Nelson batholith region are associated with ores which, in the Rossland, Salmo, Ymir and Nelson areas are almost half of the Pb, Zn, Ag type and in the Ainsworth-Slocan districts, entirely of the Pb, Zn, Ag type. It is in the Ainsworth-Slocan districts furthermore, that lamprophyres are perhaps most densely concentrated and show the closest time relation to ore. The lamprophyres along the east-side of the Coast Range batholith provide most of the evidence indicating that post-ore lamprophyres are predominantly associated with ores containing Au and Cu. The conclusion seems inescapable that lamprophyres are concentrated in the two most intensely mineralized zones of the province. Furthermore, a marked affinity is shown by lamprophyres for those areas in which Pb, Zn, Ag mineralization either is prominent or, at least, is present along with other metals. These statistical facts suggest that the relation between ore and lamprophyres is not purely one of chance and they arouse our curiosity as to what reasons may exist for such a relationship.
Broken rotational symmetry in the pseudogap phase of a high-Tc superconductor
Creators: name: Daou, R.
name: Chang, J.
name: LeBoeuf, David
name: Cyr-Choiniere, Olivier
name: Laliberte, Francis
name: Doiron-Leyraud, Nicolas
name: Ramshaw, B. J.
name: Liang, Ruixing
name: Bonn, D. A.
name: Hardy, W. N.
name: Taillefer, Louis
Publisher: name: arXiv
Year: 2009
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The nature of the pseudogap phase is a central problem in the quest to understand high-Tc cuprate superconductors. A fundamental question is what symmetries are broken when that phase sets in below a temperature T*. There is evidence from both polarized neutron diffraction and polar Kerr effect measurements that time- reversal symmetry is broken, but at temperatures that differ significantly. Broken rotational symmetry was detected by both resistivity and inelastic neutron scattering at low doping and by scanning tunnelling spectroscopy at low temperature, but with no clear connection to T*. Here we report the observation of a large in-plane anisotropy of the Nernst effect in YBa2Cu3Oy that sets in precisely at T*, throughout the doping phase diagram. We show that the CuO chains of the orthorhombic lattice are not responsible for this anisotropy, which is therefore an intrinsic property of the CuO2 planes. We conclude that the pseudogap phase is an electronic state which strongly breaks four-fold rotational symmetry. This narrows the range of possible states considerably, pointing to stripe or nematic orders.
description: Published version. Journal reference and DOI added
title: Uso de complemento alimentar nas primeiras horas de vida associado ao aparecimento de refluxo gastroesofágico em recém-nascidos nos primeiros 2 meses de vida: Scoping Review
Creators: name: Katarine Florêncio De Medeiros
name: De Lima, Maria Eliane Alves Fernandes
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Medicine and Health Sciences

description: Trata-se de um protocolo de revisão de escopo que objetiva investigar a possível relação entre o uso de complemento alimentar nas primeiras horas de vida e o desenvolvimento de refluxo gastroesofágico (RGE) em recém-nascidos durante os primeiros dois meses de vida. O termo "complemento alimentar" refere-se a qualquer tipo de alimento que seja administrado além do leite materno, incluindo fórmulas infantis, suplementos ou outros líquidos. Esta revisão consultará estudos disponiveis na literatura, incluindo pesquisa como ensaios clínicos randomizados e não-randomizados, estudos quantitativos, pesquisa de campo e estudos de revisão. O período de análise será limitado aos primeiros dois meses de vida dos recém-nascidos, uma vez que este é um período crítico de desenvolvimento gastrointestinal. O refluxo gastroesofágico é uma condição comum em bebês, caracterizada pelo retorno involuntário do conteúdo gástrico para o esôfago. Embora seja frequentemente considerado normal em recém-nascidos, em alguns casos pode causar desconforto significativo e complicações de saúde. Portanto, compreender os potenciais fatores de risco, como o uso de complemento alimentar precoce, é de suma importância para orientar práticas clínicas e políticas de saúde pública. A revisão seguirá as diretrizes metodológicas para revisões de escopo proposto pela JBI Institute Reviewer’s Manual (JBI, 2020), segundo quadro teórico proposto por Arksey e O’Malley (2005), incluindo a identificação abrangente e sistemática da literatura relevante, a extração de dados significativos e a análise temática dos resultados. Além disso, serão destacadas lacunas na pesquisa existente e identificadas áreas para futuras investigações. Os resultados desta revisão têm o potencial de informar profissionais de saúde, pais e cuidadores sobre a relação entre o uso de complemento alimentar nas primeiras horas de vida e o risco de refluxo gastroesofágico em recém-nascidos. Essas descobertas podem contribuir para estratégias de prevenção e manejo mais eficazes dessa condição clínica comum na primeira infância.
title: ÐÑÐ±Ð¾Ñ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð²Ð½Ð¾Ð³Ð¾ Ð¸ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ñ ÑÑÐ°ÑÐ¾ÑÐ° ÑÑÑÐ±Ð¾Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ° Ð¼Ð¾ÑÐ½Ð¾ÑÑÑÑ 660 ÐÐÑ Ñ Ð²Ð¾Ð´Ð¾ÑÐ¾Ð´Ð½ÑÐ¼ Ð¾Ñ Ð»Ð°Ð¶Ð´ÐµÐ½Ð¸ÐµÐ¼
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: ÐÐµÑÐµÐ·Ð½ÐµÐ², ÐÐ»ÐµÐºÑÐµÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð­Ð»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¼Ð°ÑÐ¸Ð½Ñ
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description: ÐÐ° Ð´Ð°Ð½Ð½ÑÐ¹ Ð¼Ð¾Ð¼ÐµÐ½Ñ Ð¾Ð´Ð½Ð¸Ð¼ Ð¸Ð· Ð½Ð°Ð¸Ð±Ð¾Ð»ÐµÐµ Ð¿ÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ð½ÑÑ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ð¹ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÑÐ»ÐµÐºÑÑÐ¾Ð¼Ð°ÑÐ¸Ð½Ð¾ÑÑÑÐ¾ÐµÐ½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ Ð¾Ð¿ÑÐ¸Ð¼Ð¸Ð·Ð°ÑÐ¸Ñ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸ Ð¸ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ðµ ÐµÐ´Ð¸Ð½Ð¸ÑÐ½Ð¾Ð¹ Ð¼Ð¾ÑÐ½Ð¾ÑÑÐ¸ ÑÑÑÐ±Ð¾Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ¾Ð² Ñ Ð²Ð¾Ð´Ð¾ÑÐ¾Ð´Ð½ÑÐ¼ Ð¾ÑÐ»Ð°Ð¶Ð´ÐµÐ½Ð¸ÐµÐ¼. Ð ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð²Ð°ÑÐ¸Ð°Ð½ÑÑ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð²Ð½Ð¾Ð³Ð¾ Ð¸ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ñ ÑÑÐ°ÑÐ¾ÑÐ° ÑÑÑÐ±Ð¾Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ° Ð¼Ð¾ÑÐ½Ð¾ÑÑÑÑ 660 ÐÐÑ. ÐÐ° Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð½ÑÑ ÑÐ»ÐµÐºÑÑÐ¾Ð¼Ð°Ð³Ð½Ð¸ÑÐ½ÑÑ, ÑÐµÐ¿Ð»Ð¾Ð²ÑÑ Ð¸ Ð¼ÐµÑÐ°Ð½Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ°ÑÑÐµÑÐ¾Ð² Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ð¾ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð²Ð½ÑÑ Ð¸ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ð¹ ÑÑÐ°ÑÐ¾ÑÐ° ÑÑÑÐ±Ð¾Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ° Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½ Ð¾Ð¿ÑÐ¸Ð¼Ð°Ð»ÑÐ½ÑÐ¹ Ð²Ð°ÑÐ¸Ð°Ð½Ñ.
Thrombotic events in models GATA-1 low myelofibrosis characterized by altered localization of P-selectin during megakaryocyte development
Creators: name: Sancillo, L.
name: Zingariello, M.
name: Zetterberg, E.
name: Verrucci, M.
name: Bosco, D.
name: Migliaccio, A.R.
name: Rana, R.A.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014
Subjects: Myelofibrosis; Megakaryocytes; P-Selectin

description: Patients with primary myelofibrosis (PMF) have increased risk for bleeding and thrombosis. It is debated whether propensity to thrombosis is due to increased numbers of platelet microparticles and/or to pathological platelet-neutrophil interactions.This interactions are mediated by P-selectin and even though the megakaryocytes(Mk)of MF patients express normal levels of P-selectin,it remains abnormally localized to the DMS rather than being assembled into the a-granules in platelets.Mice carrying the hypomorphic Gata1low mutation express the same Mk abnormalities presented by PMF patients,including abnormal P-selectin localization to the DMS and develop with age myelofibrosis,that closely resembles human PMF.The aim of this study was to determine whether Gata1low mice would develop thrombosis with age and,in this case,the role played by P-selectin in the development of the trait.To this aim,Gata1low mice were crossed with P-selnull mice according to standard genetic protocols and Gata1lowP-selWT,Gata1lowP-selnull and Gata1WTP-selnull or Gata1WTP-selWT littermates obtained.Platelet count,hematocrit as well as platelet microparticle levels were determined on all the different mutants.It was shown that platelet counts are reduced in Gata1low mice.Moreover,platelet microparticles are reduced in Gata1low mice and P-selectin positive platelet microparticles were not found.The presence of thrombosis was determined by immunohistological staining of organs.Gata1low mice with or without the P-selectin null trait had a prolonged bleeding time and thrombosis was seen adult and old Gata1low mice,but the Gata1low/P-selnull mice were rescued.Thus,presence of the P-selectin null trait rescued Gata1low mice from the thrombotic phenotype,but did not change level of platelet microparticles.All these data indicate that abnormal localization of P-selectin,induced by the Gata1low mutation,and thus, increased pathological interactions with leucocytes,is responsible for the increased presence of thrombosis seen in these mice.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
Additional file 1 of Antiviral therapy inhibited HBV-reactivation and improved long-term outcomes in patients who underwent radiofrequency ablation for HBV-related hepatocellular carcinoma
Creators: name: Liu, Jian
name: Shen, Hao
name: Huang, Shengyu
name: Lin, Jianbo
name: Yan, Zhenlin
name: Qian, Guojun
name: Lu, Zhenghua
name: Wan, Xuying
name: Zhang, Fabiao
name: Wang, Kui
name: Zhang, Yongjie
name: Li, Jun
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 1: Supplementary Table 1. AVT medication with nucleos(t)ide analogues. Supplementary Table 2. Baseline characteristics of AVT and Non-AVT. Supplementary Table 3. Analysis of independent risk factors for AVT. Supplementary Table 4. Analysis of independent risk factors for local recurrence. Supplementary Table 5. Analysis of independent risk factors for distant recurrence.
Mesenchymal stromal cells and their paracrine factors regulate MMP-2 and MMP-9/ TIMP-2 balance in skeletal myoblasts and fibroblasts: new insights into the potential role of MSC-cell therapy in muscle regenerative medicine
Creators: name: Sassoli, Chiara
name: Nosi, Daniele
name: Tani, Alessia
name: Chellini, Flaminia
name: Mazzanti, Benedetta
name: Quercioli, Franco
name: Formigli, Lucia
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014
Subjects: matrix metalloproteinases (MMPs); mesenchymal stromal cells (MSCs); myoblast differentiation; satellite cells; skeletal fibroblasts

description: Recent studies showed that mesenchymal stromal cell (MSCs) transplantation improves healing of injured and diseased skeletal muscle, although the mechanisms of benefit are still poorly understood. In the present study, we investigated whether MSCs and/or their trophic factors were able to regulate matrix metalloproteinase (MMPs) expression and activity in different cells of the muscle tissue. It was found that MSCs in co-culture with C2C12 cells up-regulated MMP-2 and MMP-9 expression and function in the myoblastic cells; these effects were concomitant with the down-regulation of the tissue inhibitor of metalloproteinases (TIMP)-2. Similar results were obtained upon incubation of conditioned medium from MSCs (MSC-CM) or in experiments where MSCs were separated from myoblasts by polycarbonate membranes, enabling diffusion of soluble factors while preventing the physical contact between the two cell types, suggesting that MSCs regulated MMP/TIMP balance in skeletal myoblasts by paracrine factors. In the single muscle fibre experiments, MSC-CM administration increased MMP-2 and MMP-9 expression in Pax-7+ satellite cells and stimulated their mobilization, differentiation and fusion into multinucleated myotubes. The anti-fibrotic properties of MSC-CM involved also the regulation of MMPs by skeletal fibroblasts and the inhibition of their differentiation into myofibroblasts, as detected by reduced expression of α-smooth actin and type-I collagen in the fibroblasts incubated with MSC-CM. These findings add novel information on the effects of MSCs on the skeletal muscle healing, suggesting that growth factors and cytokines released by these cells may modulate the fibrotic response and improve the endogenous mechanisms of muscle repair/regeneration.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
Rotochemical heating in millisecond pulsars: modified Urca reactions with uniform Cooper pairing gaps
Creators: name: Petrovich, Cristobal
name: Reisenegger, Andreas
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Context: When a rotating neutron star loses angular momentum, the reduction in the centrifugal force makes it contract. This perturbs each fluid element, raising the local pressure and originating deviations from beta equilibrium that enhance the neutrino emissivity and produce thermal energy. This mechanism is named rotochemical heating and has previously been studied for neutron stars of nonsuperfluid matter, finding that they reach a quasi-steady configuration in which the rate at which the spin-down modifies the equilibrium concentrations is the same at which neutrino reactions restore the equilibrium. Aims: We describe the thermal effects of Cooper pairing with spatially uniform energy gaps of neutrons Δ_n and protons Δ_p on the rotochemical heating in millisecond pulsars (MSPs) when only modified Urca reactions are allowed. By this, we may determine the amplitude of the superfluid energy gaps for the neutron and protons needed to produce different thermal evolution of MSPs. Results: We find that the chemical imbalances in the star grow up to the threshold value Δ_{thr}= min(Δ_n+ 3Δ_p, 3Δ_n+Δ_p), which is higher than the quasi-steady state achieved in absence of superfluidity. Therefore, the superfluid MSPs will take longer to reach the quasi-steady state than their nonsuperfluid counterparts, and they will have a higher a luminosity in this state, given by L_γ~ (1-4) 10^{32}Δ_{thr}/MeV \dot{P}_{-20}/P_{ms}^3 erg s^-1. We can explain the UV emission of the PSR J0437-4715 for 0.05 MeV
description: (accepted version to be published in A&A)
title: The Impact of Team-Based Learning’s Readiness Assurance Process on Virtually Isolated Adults
Creators: name: Barclay, Matthew W.
Publisher: name: Utah State University
Year: 2011

description: The purpose of this study was to test the effectiveness of the readiness assurance process of team-based learning (TBL) in virtually isolated settings. Many Internet sites offer courses for adults to use on their own without access to mentors or other learners. However, educational theory suggests that people learn better with others than by themselves. The focus of this investigation was whether the inclusion of the readiness assurance process would increase participants’ levels of learning based on Bloom’s revised taxonomy within the limits of virtual isolation.
In this study an experimental pretest-posttest design was employed. Using a 2- day mini-course about listening in marriage, 117 participants were randomly assigned to three groups. In the TBL group, married couples worked together following the principles of the readiness assurance process. In the independent group, one spouse from a marriage worked alone, also following the principles of the readiness assurance process. In the baseline group, one spouse from a marriage took the pretest and posttest only.
The first posttest, called posttest-L, measured lower levels of learning (remembering and understanding). The second posttest, called posttest-D, measured deeper learning (applying and evaluating). Using ANCOVA with the pretests as the covariates, results showed a statistically significant difference in learning gains between the TBL group and the independent group for lower levels of learning (ES = .39). However, statistical significance was not achieved for deeper learning. Moreover, TBL scores and independent scores were no different from the baseline scores for measures of deeper learning. Along with explanations for these results, limitations of the study are described and suggestions for future research are offered.