cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Entropy-Space: Time and Space as Emergent Structures
Creators: name: Cambi, Pietro
Publisher: name: Zenodo
Year: 2025

description: In this work, we present a new paradigm in which time ceases to be a fundamental parameter and is replaced by entropy as the main evolutionary variable.

In this way, the geometry of space-time is replaced by an entropic metric, in which the irreversible growth of entropy drives the gravitational dynamics.

Our approachrepresents a radical extension of the idea of entropic hysteresis, already proposed in a previous study, and connects the concepts of emergent gravity, the holographicprinciple, and Loop Quantum Gravity (LQG).

We provide the mathematical formulation, describe possible numerical simulations, where the temporal coordinate is replaced by S, and offer testable predictions for phenomena such as dark matter, dark energy, and the Hubble tension. We then complete the picture with a philo sophical reflection on the nature of time and causality, and a broad bibliographical comparison with the most recent findings in this field.
Chromatische Fantasie für das Pianoforte [d-moll BWV 903]
Creators: name: Bach, Johann Sebastian
Publisher: name: C.F. Peters
Year: 1820

description: III. Instrumentalmusik. 9. Für Klavier
description: [einige Bemerkungen über den Vortrag der chromatischen Fantasie von F. Griepenkerl]
Additional file 7 of The effectiveness and efficiency of asymptomatic SARS-CoV-2 testing strategies for patient and healthcare workers within acute NHS hospitals during an omicron-like period
Creators: name: Evans, Stephanie
name: Naylor, Nichola R.
name: Fowler, Tom
name: Hopkins, Susan
name: Robotham, Julie
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 7
Retinoic acid sensitizes acute myeloid leukemia cells to ER stress
Creators: name: Masciarelli, Silvia
name: Capuano, Ernestina
name: Bellissimo, Teresa
name: Ottone, Tiziana
name: Divona, Maria Domenica
name: Lo Coco, Francesco
name: Fazi, Francesco
Publisher: name: Firenze University Press
Year: 2017
Subjects: AML; ER stress; RA; ATO

description: Acute myeloid leukemia (AML) is caused by the blockade of hematopoietic myeloid precursors at different stages of differentiation. A subtype of AML, acute promyelocytic leukemia (APL), is a paradigm of differentiation therapy since retinoic acid (RA) is able to induce leukemic blast terminal differentiation leading to cure rates exceeding 80% when administered in combination with chemotherapy. Although APL patients refractory to RA or who relapsed are very effectively treated with arsenic trioxide (ATO) in combination with RA, the elevated costs limit its use in developing countries and in first line therapy so that RA plus chemotherapy currently remain the standard of care (1, 2). Most importantly non-APL acute myeloid leukemia do not respond to RA indicating the need for novel strategies to sensitize AML cells to RA. Here we show that RA-triggered differentiation of APL cells induces endoplasmic reticulum (ER) stress slightly activating the unfolded protein response (UPR). This is sufficient to render leukemic cell lines and human primary blasts very sensitive to doses of ER stress inducing drugs, like tunicamycin (Tm), that are not toxic for the same cells in the absence of RA or for most cell types. Furthermore we observed that low doses of Tm, even in the absence of RA, are sufficient to strongly increase ATO toxicity. Indeed both RA-sensitive and RA-resistant APL cell lines resulted sensitive to Tm-ATO combined treatment at low doses of ATO that are ineffective in the absence of ER stress. The use of inhibitors targeting specific UPR branches indicate that the Protein Kinase RNA-like Endoplasmic Reticulum kinase (PERK) pathway protects differentiating APL cells from ER stress rendering it an interesting therapeutic molecular target. Finally, we extended our observations in a non-APL model, assessing that RA sensitize the non-APL cell line HL60 to ER stress. Altogether our data indicate ER stress as a possible target for designing novel combination therapeutic strategies in AML. Contribution of AIRC (StG 4841) and FILAS-RU-2014-1020 to FF was greatly appreciated.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Supplemental Material - Becoming a Rare Disease Parent: An Interpretative Phenomenological Analysis of Parent-Caregivers’ Postpartum Experiences
Creators: name: Davidson, Hannah Rochelle
name: Gelles, Shani
name: Keller, Krystyna R.
name: Zajdel, Melissa
name: Koehly, Laura M.
Publisher: name: SAGE Journals
Year: 2023
Subjects: Nursing not elsewhere classified
Public Health and Health Services not elsewhere classified
Sociological Methodology and Research Methods

description: Supplemental Material for Becoming a Rare Disease Parent: An Interpretative Phenomenological Analysis of Parent-Caregivers’ Postpartum Experiences by Hannah Rochelle, Davidson, Shani, Gelles, Krystyna R., Keller, Melissa, Zajdel, and Laura M., Koehly in Qualitative Health Research
Additional file 1 of Educational interventions for imposter phenomenon in healthcare: a scoping review
Creators: name: Siddiqui, Z Kamran
name: Church, H. R
name: Jayasuriya, R.
name: Boddice, T.
name: Tomlinson, J.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 1. Phase 1 Search in Ovid MEDLINE (conducted on August 10, 2022) and number of articles yielded.
Antitumoral effects of Hibiscus Sabdariffa on human breast cancer cells
Creators: name: Erriquez, Jacopo
name: Malacrida, Alessio
name: Rodriguez Menendez, Virginia
name: Nicolini, Gabriella
name: Miloso, Mariarosaria
Publisher: name: Firenze University Press
Year: 2017
Subjects: Hibiscus sabdariffa; human breast cancer cells

description: Hibiscus Sabdariffa (HS) is a plant commonly used in folk medicine (1). In recent years HS has gained great interest due to its important antioxidant, anti-inflammatory and antitumoral properties. In our work, we evaluated the in vitro anticancer effects of HS extract against two different human breast cancer cell lines: estrogen receptor (ER) positive MCF-7 cells and ER negative MDA-MB-231 cells. We tested both total extract (HSE) and one fraction obtained by ethyl acetate extraction (HSEC). MTT assay and Trypan Blue vital count showed a dose and time dependent reduction of the viability in both cell lines treated with different concentrations of HSE or HSEC compared to untreated control cells. A significantly marked reduction was observed in MCF-7 cells treated with HSEC. On the basis of our results we used the concentrations of 7.5mg/ml and 3.5mg/ml respectively for HSE and HSEC. In order to evaluate ER involvement in HS effect, we analyzed the cellular localization of the receptor (ERα isotype) by immunofluorescence experiments. Untreated MDA-MB-231 cells showed a low expression of the receptor mostly localized at the cytoplasmic level and treatment with HSE or HSEC didn’t change this state. Untreated MCF-7 cells showed a greater expression of the receptor, with nuclear and cytoplasmic localization. Following HSE or HSEC treatment ERα localization became more cytoplasmic and this effect was more evident after HSEC induction. These data were also confirmed by ERα western blot analysis. Subsequently, we studied HSE and HSEC ability to alter migration and invasion capacity of ER positive MCF-7 cells. Using a scratch wound healing assay we did not observe any change in the migration of cells compared to untreated cells. On the contrary, in a Boyden chamber invasion assay, HSE, and especially HSEC, induced reduction of MCF-7 cell invasion. In conclusion, we have demonstrated that HS is able to reduce cell viability of ER positive MCF-7 and ER negative MDA-MB-231 cells. This effect is more evident in MCF-7 cells in which ER localization and reduced cell invasion were observed. These results are more evident after HSEC treatment. Further studies will be needed to better elucidate the involved mechanisms of action.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Quali-Quantitative Variations In \Textit{Constrictotermes Cyphergaster} Instars (Termitidae, Nasutitermitinae) In Dryland Caatinga Vegetation In Northeastern Brazil
Creators: name: Lucena, Emanuelly Félix de
name: Vasconcellos, Alexandre
name: Moura, Flávia Maria da Silva
Publisher: name: Zenodo
Year: 2017
Subjects: Population
Seasonality
Neotropical

description: \textit{Constrictotermes cyphergaster} is a termite species that constructs arboreal nests and is very abundant in Caatinga vegetation. We investigated the quali-quantitative temporal variations in \textit{C. cyphergaster} instars in nests collected in the municipality of São João do Cariri, Paraíba State, Brazil. Five nests were collected every 60 days between October/2011 and August/2012, totaling 30 nests. To estimate nest populations, five subsamples of 5 ml were removed from each colony and all of the instars counted. The nests had mean volumes of 75.1 ± 25.0 L. Their total estimated populations varied from 23,021 to 128,113 individuals/nest. The apterous population varied from 22,958 to 127,178 individuals/nest, and the nymphal population varied from 0 a 5,109 individuals/nest. There were significant differences in the populations of workers, soldiers, pre-soldiers, larvae 2, nymphs 5, and alates during the different months of the year. Workers, pre-soldiers, and larvae 2 were most abundant in February, and soldiers in April. In relation to the presence of nymphal instars: N1 were present in April and June; N2 and N3 were absent in October and December; N5 were present in December and February; and alates were observed only in February. The fourth nymphal instar were observed throughout the year. As February was the month with the greatest rainfall, our results should reflect a high energetic investment in terminal nymph instar differentiation before swarming; with subsequent greater differentiation of apterous lineage and initial nymphal instars.
Correlation between Protein Kinase Cε expression and thrombotic risk in Primary Myelofibrosis (PMFs)
Creators: name: Carubbi, Cecilia
name: Martini, Silvia
name: Masselli, Elena
name: Galli, Daniela
name: Pozzi, Giulia
name: Gobbi, Giuliana
name: Mirandola, Prisco
name: Vitale, Marco
Publisher: name: Firenze University Press
Year: 2017

description: Myelofibrosis (MF) - either primary (PMF) or arising from a previous PV or ET - is a Philadelphia-negative MPNs characterized by aberrant platelet production and consequent variable platelet count with altered hemostatic function (1). It has already been demonstrated that the risk of thrombotic events is one of the most common co-morbidities associated with PV and ET (2-5). However, risk of thrombotic events in PMF has not been investigated yet. We previously demonstrated that PKCepsilon (PKCε) is over-expressed in platelets from patients with acute myocardial infarction and accounts for their increased reactivity (6). Additionally, we recently showed that PKCε overexpression plays a crucial role in PMF MK impaired differentiation and that its levels correlated with the disease severity (expressed by the IPSS/DIPPS risk category) (7,8). On these bases, we analyzed PKCε expression in platelets from PMF patients, investigating a potential correlation with thrombotic risk and the aggressiveness of the disease. For this study, peripheral blood samples from 6 PMF patients and 3 healthy donors (HD) were collected in Na-citrate tubes. PKCε mRNA and protein levels were determined in platelets purified as described by Carubbi C, 2012. Finally, patients are stratified according to the history of cardio-vascular events and the IPSS/DIPSS risk category. PMF platelets showed significantly higher mRNA levels of PKCε as compared to HD. Protein analysis confirm PKCε over-expression in PMF platelets, almost reaching statistical significance. We then found that platelet from PMF patients who suffered from cardiovascular events display significantly higher levels of PKCε as compared to the one with a negative history. Finally, similarly to what observed in PMF magakaryocytes, we showed a positive correlation between PKCε platelets levels and IPSS/DIPSS risk category, with the lowest levels in low-risk patients and higher levels in high-risk patients. Collectively, our preliminary results indicate that PMF platelets show an aberrant expression of PKCε which correlates with the disease burden and a history of cardiovascular events. This suggests that the over-expression of PKCε may account for PMF platelet altered reactivity and function.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Arrenurus (Truncaturus) fontinalis Viets 1920
Creators: name: Esen, Yunus
name: Pešić, Vladimir
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Arrenuridae
Arrenurus
Arrenurus fontinalis

description: Arrenurus (Truncaturus) fontinalis Viets, 1920
Materials examined: Elazığ Province, Sivrice district, Sürek village, spring, 38°27'05" N, 39°21'49" E, 1290 m a.s.l., 13.07.2013, (1/1/0).
Records from Türkiye: Erzurum (Erman et al., 2010), Malatya (Esen and Erman, 2012), Antalya (Boyacı et al., 2012), Bingöl (Esen and Erman, 2013), Erzincan (Esen et al., 2013), Burdur (Gülle et al., 2017) and Isparta (Durucan and Boyacı, 2020).
description: Published as part of Esen, Yunus & Pešić, Vladimir, 2024, Contributions to the knowledge of the water mite fauna (Acariformes, Hydrachnidia) of Türkiye with descriptions of two new species, pp. 24-33 in Acarological Studies 6 (1) on page 31, DOI: 10.47121/acarolstud.1387311, http://zenodo.org/record/12192669
PKC epsilon involvement in Th17 in vitro differentiation: implications in psoriasis pathogenesis
Creators: name: Galli, Daniela
name: Martini, Silvia
name: Pozzi, Giulia
name: Masselli, Elena
name: Carubbi, Cecilia
name: Gobbi, Giuliana
name: Mirandola, Prisco
name: Vitale, Marco
Publisher: name: Firenze University Press
Year: 2017

description: Psoriasis is a noncontagious, arytematous-squamose dermatitits affecting both sexes and all races. Although its exact etiology is largely unknown, it is now recognized as one of the most common immune-mediated disorders and several studies demonstrate an impairment of regulatory T-cells (Tregs) function and an up-regulation of IL-17 levels produced by T-helper 17 lymphocytes (Th17)(1,2). Protein kinase C epsilon (PKCε) is a serine/threonine kinase which plays a key role in the proliferation and differentiation of epidermal cells. We have previously demonstrated a role for PKCε in the pathogenesis of the autoimmune disease Hashimoto’s thyroiditis (3). PKCε is over-expressed in CD4+ T lymphocytes isolated from PBMC fraction in patients affected by this pathology and its forced down-modulation primed the TGF-mediated in vitro Treg polarization of human T CD4+ cells. Since it has been demonstrated that PKC-signalling is altered in psoriatic keratinocytes (4), we investigated the involvement of PKCε in Th17 in vitro differentiation and its potentially implication in immune response correlated to psoriasis. Using western blot and real time PCR, we have observed that PKCε protein levels and mRNA increase during Th17-lineage in vitro differentiation from naïve CD4+ T cells with a similar trend of Th17 markers of differentiation STAT3 and RoRyT. Moreover, PKCε overexpression significantly increases STAT3 and phosphorylated STAT3 levels, suggesting that PKCε boosts Th17 polarization. Thereafter, we sought to investigate PKCε expression in CD4+ lymphocytes obtained from peripheral blood of psoriatic patients and we observed that PKCε expression levels are significantly higher compared with healthy donors. Intriguingly, we observed a closely correlation of PKCε expression with PASI index, suggesting an involvement of the kinase with the severity of the disease. Collectively these data suggest that PKCε might be involved in Th17 differentiation, that it could be a key factor to regulate Th17 pathological expansion and therefore a potential psoriatic pharmacological target.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
title: This is so contemporary? Konzepte von Moderne und Zeitgenossenschaft bei Jeff Wall
Creators: name: Dobbe, Martina
Publisher: name: Kunstgeschichte und Zeitgenossenschaft
Year: 2017
Subjects: Zeitgenossenschaft; Moderne; Modernekritik; Jeff Wall; Mies van der Rohe

description: Zeitgenossenschaft und das Zeitgenössische werden seit den 1990er-Jahren sowohl in der Bildenden Kunst, als auch in den Kunstwissenschaften diskutiert. Vor diesem Hintergrund untersucht Martina Dobbe, wie sich Zeitgenossenschaft über die Revision oder Kritik der Modernekritik erschließt. An Jeff Walls „Morning Cleaning. Mies van der Rohe Foundation Barcelona“ (1999) – einer Arbeit, die Modernekritiken der 1920er-, der 1960er- und der
 1980er-/90er-Jahre synthetisiert – exemplifiziert die Autorin, ob die (jeweilige) Modernekritik im einschließenden oder ausschließenden Sinne von Moderne und Zeitgenossenschaft spricht.
description: Kunstgeschichte und Zeitgenossenschaft, Ausgabe 1
Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin
Creators: name: Cervia, Davide
name: Moscheni, Claudia
name: De Palma, Chiara
name: Giovarelli, Matteo
name: Procacci, Patrizia
name: Clementi, Emilio
name: Perrotta, Cristiana
Publisher: name: Firenze University Press
Year: 2017
Subjects: A-SMase; melanoma; autophagy; mTOR; chemo-resistance

description: In advanced stages, melanoma is still a therapeutic challenge, despite the large number of chemotherapeutic regimens so far developed. Single drug chemotherapy is in many cases ineffective and combinations of chemotherapeutic drugs have demonstrated response rates only marginally higher, and at the cost of systemic toxicity. The new targeted therapies and immunotherapies have shown better efficacy and have supplanted chemotherapy as first-and second-line therapy. However, since melanoma cells eventually become resistant also to these novel therapies, the quest for new, more effective and possibly less toxic approaches is still open. The sphingolipid metabolising enzyme Acid Sphingomyelinase (A-SMase) has been recently shown to inhibit melanoma progression and correlate inversely to tumour grade [1]. We have investigated the role of A-SMase in the chemo-resistance to anticancer treatment using mice with melanoma allografts and melanoma cells differing in terms of expression/activity of A-SMase. Furthermore, as autophagy is a crucial determinant of the melanoma sensitivity to chemotherapeutic drugs, we have also investigated whether an action of A-SMase in autophagy can explain its role [2]. Melanoma sensitivity to chemotherapeutic agent cisplatin in terms of cell viability/apoptosis, tumour growth, and animal survival depended directly on the A-SMase levels in tumoural cells. A-SMase action was due to inhibition of autophagy through activation of Akt/mammalian target of rapamycin (mTOR) pathway. Treatment of melanoma-bearing mice with the autophagy inhibitor chloroquine restored sensitivity to cisplatin of tumours expressing low levels of A-SMase while no additive effects were observed in tumours characterised by sustained A-SMase levels. In conclusion A-SMase, affecting mTOR-regulated autophagy and playing a central role in cisplatin efficacy, is an attractive target in anti-tumour strategy for melanomas and our data encourage pre-clinical testing of the modulation of A-SMase levels/activity as possible novel anti-neoplastic strategy.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Magnesium homeostasis goes awry in chemoresistance -TRPM6, TRPM7 and MagT1 in colon carcinoma LoVo cells
Creators: name: Moscheni, Claudia
name: Cazzaniga, Alessandra
name: Locatelli, Laura
name: Sargenti, Azzurra
name: Trapani, Valentina
name: Sartori, Patrizia
name: Castiglioni, Sara
Publisher: name: Firenze University Press
Year: 2017
Subjects: Magnesium; drug resistance; colon carcinoma; magnesium transporters

description: Chemoresistance is one of the most significant factors impeding the progress of cancer therapy (1). It is known that neoplastic cells accumulate magnesium and frequently upregulate one of its transporters, i.e.TRPM7 (2). We have investigated magnesium homeostasis in a model of chemoresistance i.e. colon carcinoma LoVo cells sensitive (LoVo-S) or resistant to doxorubicin (LoVo-R). We observed that LoVo-R have higher amount of total intracellular magnesium than LoVo-S. We studied the expression of some magnesium transporter (TRPM6, TRPM7 and MagT1) by Real Time PCR and Western Blot and found that TRPM6 and 7 are overexpressed in LoVo-S, while MagT1 is upregulated in LoVo-R. In LoVo-S, silencing TRPM7 retards cell growth and shifts the phenotype to one more similar to resistant cells. On the other hand, calpeptin, a calpain inhibitor, upregulates TRPM7, stimulated proliferation and enhances the sensitivity to doxorubicin of LoVo-R. Silencing MagT1 in LoVo-R markedly inhibited cell growth without affecting the response to doxorubicin. We conclude that alterations of magnesium homeostasis play a role in drug resistance.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Additional file 2 of Educational interventions for imposter phenomenon in healthcare: a scoping review
Creators: name: Siddiqui, Z Kamran
name: Church, H. R
name: Jayasuriya, R.
name: Boddice, T.
name: Tomlinson, J.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 2. Raw Data Set from the Scoping Review.
Genotoxicity and cytotoxicity of Aloysia polystachia: an in vivo study in rabbits
Creators: name: Santoro, Antonietta
name: Palazzo, Marisa
name: Vizzarri, Francesco
name: Nicolin, Vanessa
name: Nori, Stefania Lucia
Publisher: name: Firenze University Press
Year: 2017
Subjects: Aloysia polystachia; genotoxicity; rabbit

description: In the search of new compounds useful for the treatment of neurological disorders, medicinal plant research has progressed widely in the last decade, particularly because of the hypothesis that natural extracts possess a low or absent toxicity. Aloysia polystachia (Griseb.) Moldenke belonging to the family of Verbenaceae has been used in the traditional medicine for a variety of indications and as a sedative. Recently, some evidence reported that it exhibits some antidepressant- and anxiolytic-like effects involving the modulation of GABA system in preclinical studies in mice (1). However no investigations have been performed on its (geno)toxicity in long-term studies as it would be required for its use in neurological pathologies. In this study, we investigated the genotoxic potential of a water soluble extract of Aloysia polystachia leaves, administered orally every day for 90 days to 20 New Zealand white rabbits homogeneous for weight and age. Subjects were divided into four groups: the control group, and three experimental groups fed with a diet supplemented with 1g/kg; 1.5 g/kg and 2g/kg of Aloysia Polystachia, then peripheral blood was drawn from the vein auricularis marginalis before and after 45 and 90 days of treatment. Cytogenetic analysis was performed on each subject at each time point and chromosome aberrations (structural and numerical) and mitotic index were used as a measure of DNA damage and cytotoxicity (2). Results indicated that Aloysia polystachia extract induces a significant increase in the percentage of aberrant cells as well as in the aberration frequency (mainly chromatid breaks and fragments) associated with a decreasing trend of the mitotic index. The DNA damage was particularly higher after the first 45 days of treatment whereas it remains significantly high but almost unvaried until the end of the treatment. These data suggest that Aloysia polystachia extract has genotoxic and cytotoxic activity, even though further investigations are required to assess which compound of the extract could be responsible for the observed effects.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
sj-docx-1-pbi-10.1177_10983007231200542 – Supplemental material for CICO-Secondary: A Single-Case Experimental Study in High School
Creators: name: Kittelman, Angus
name: Cohen Lissman, Dana
name: Strickland-Cohen, M. Kathleen
name: McGrath Kato, Mimi
name: Flannery, K. Brigid
name: Horner, Robert H.
name: Izzard, Sara
name: St. Joseph, Stephanie
name: Mowery, Aaron
Publisher: name: SAGE Journals
Year: 2023
Subjects: Education
Psychology not elsewhere classified
Special Education and Disability

description: Supplemental material, sj-docx-1-pbi-10.1177_10983007231200542 for CICO-Secondary: A Single-Case Experimental Study in High School by Angus Kittelman, Dana Cohen Lissman, M. Kathleen Strickland-Cohen, Mimi McGrath Kato, K. Brigid Flannery, Robert H. Horner, Sara Izzard, Stephanie St. Joseph and Aaron Mowery in Journal of Positive Behavior Interventions
Additional file 3 of Educational interventions for imposter phenomenon in healthcare: a scoping review
Creators: name: Siddiqui, Z Kamran
name: Church, H. R
name: Jayasuriya, R.
name: Boddice, T.
name: Tomlinson, J.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 3. Sub analysis of workshops (n = 10) developed to address IP. Abbreviations: Prevalence exploration (PE), Understanding & awareness (U/A), Intervention development (ID), Evaluation (E), Young’s Imposter Scale (YIS), Clance Imposter Phenomenon Scale (CIPS).
Ultrastructure of mouse granulosa cells exposed in vitro to the fungicide Mancozeb
Creators: name: Palmerini, Maria Grazia
name: Nottola, Stefania Annarita
name: Miglietta, Selenia
name: Belli, Manuel
name: Bianchi, Serena
name: Maiese, Maria Carmela
name: Zhurabekova, Gulmira
name: Balmagambetova, Aru
name: Macchiarelli, Guido
Publisher: name: Firenze University Press
Year: 2017
Subjects: Mancozeb; granulosa cells; TEM; SEM; ultrastructure

description: Mancozeb is an ethylene bis-dithiocarbamate widely used as fungicide, also due to a low reported toxicity in mammals. However, reproductive toxicity has been demonstrated in vivo and in vitro in mouse oocytes, by the alteration of spindle morphology [1] and impairment of fertilizability [2]. Mancozeb exerted on mouse GCs cultured in vitro a premalignant-like status, indicated by reduced p53 expression [3] and a mild oxidative stress [4]. However, presence and extent of ultrastructural alterations induced in vitro by Mancozeb on GCs were not yet studied. To this aim, Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM) were applied on mouse GCs cultured with increasing concentration of Mancozeb. GCs were obtained by puncturing antral follicles of PMSG-treated prepubertal CD1 female mice and cultured in vitro in DMEM+5%FBS+pen/strep without (control) or with increasing concentration of Mancozeb (0.001-to-1 µg/ml) for 48hrs, at 37°C and 5%CO2. At the end of the culture period, cells were washed in PBS, fixed in 2.5% glutaraldehyde/PBS and stored at 4°C until processing. GCs were, then, subjected to standard preparative for TEM [5] and SEM [6] observation. Results showed a dose-dependent toxicity of Mancozeb on mouse GCs. Ultrastructural data showed intercellular communication retraction, irregular nuclear membrane and chromatin marginalization at lower concentrations; chromatin condensation, membrane blebbing and cytoplasmic vacuolization at higher concentrations. In conclusion, Mancozeb showed a dose-dependent harmful effect on granulosa cells in vitro, probably due to the toxic breakdown product ethylenethiourea. TEM and SEM were again confirmed to be a valuable tool to study ultrastructural alterations after toxicants exposure.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
sj-docx-1-eup-10.1177_14651165231207088 - Supplemental material for European integration and political party logos: A ‘visual Europeanization’?
Creators: name: Casiraghi, Matteo CM
name: Cusumano, Eugenio
name: Chryssogelos, Angelos
Publisher: name: SAGE Journals
Year: 2023
Subjects: International Relations
Regional Analysis and Development

description: Supplemental material, sj-docx-1-eup-10.1177_14651165231207088 for European integration and political party logos: A ‘visual Europeanization’? by Matteo CM Casiraghi, Eugenio Cusumano and Angelos Chryssogelos in European Union Politics
title: Treibhaus, Kunststall oder Hospital? Die Kunstakademie und ihr Verhältnis zur zeitgenössischen Kunst
Creators: name: Hemken, Kai-Uwe
Publisher: name: Kunstgeschichte und Zeitgenossenschaft
Year: 2017
Subjects: Kunstakademie; Patronage; Kunstmarkt; Öffentlichkeit

description: Kai-Uwe Hemken befasst sich mit der Institutionsgeschichte der Kunstakademie und ihrem spannungsgeladenen Verhältnis zu Künstlern und (autonomer) Kunst. In der Entwicklung der Akademie bis in die Gegenwart wird insbesondere die Relevanz der Entstehung eines öffentlichen Diskurses über Kunst im 18. Jahrhundert thematisiert.
description: Kunstgeschichte und Zeitgenossenschaft, Ausgabe 1
title: Vegetationsverhältnisse, Bestandesveränderungen und Naturschutzstrategien zweier ausgewählter Feuchtwiesenlandschaften im oberösterreichischen Alpenvorland
Creators: name: Zmelik, Katharina
Year: 2007

description: Feuchtgebiete sind wichtige Träger der Vielfalt von Pflanzengesellschaften und Brutvögeln (PLACHTER 1991, MATOUCH et al. 1996). Alleine in Österreich wurden jedoch aufgrund von Drainagierungsmaßnahmen alleine in den letzten 50 Jahren rund 200 000 ha Agrarfläche entwässert (STALZER 1991). Das Ziel der hier vorliegenden Arbeit war es, die pflanzensoziologische Vielfalt zweier Feuchtwiesenlandschaftsreste im Inn- und Hausruckviertel zu erheben, vegetationsökologische Veränderungen in den letzten 15 – 20 Jahren, hervorgerufen vor allem durch Nutzungsänderungen, zu analysieren und Naturschutzmaßnahmen bzw. Verbesserungen des Pflegemanagements anzuführen. Die vegetationsökologischen Erhebungen im Naturschutzgebiet „Koaserin“ bei Peuerbach und im Moosbachtal bei St. Johann am Walde erfolgten in den Jahren 2003 und 2004, des Weiteren wurden Interviews über frühere und aktuelle Nutzung der Flächen mit den bewirtschaftenden Landwirten geführt. Für die Analyse der Vegetationsveränderungen standen mir alte Vegetationsbeschreibungen beider Gebiete aus den Jahren 1985 bzw. 1989 zur Verfügung. Anhand meiner Bearbeitung konnte ich feststellen, dass der Großteil der Wiesen des Moosbachtals zu einer durch intensiven Nutzung geprägten Ausformung des Ranunculo repentis-Alopecuretum pratensis zählt. Naturschutzfachlich interessante Flächen wie Calthion-Wiesen und magere bzw. feuchtere Ausprägungen der Fuchsschwanz-Wiesen beschränken sich vor allem auf ÖPUL-geförderte Flächen (Code: Erhaltung naturschutzfachlich wertvoller Flächen). In der Koaserin wird das bewirtschaftete Grünland zumeist ebenfalls von Fuchsschwanz-Wiesen eingenommen. Die Stilllegung von ehemals bewirtschafteten Wiesen hatte eine Zunahme von höherwüchsigen Brache-Gesellschaften wie Rohrglanzgras-, Brennessel- und Schlankseggenbeständen zur Folge. Im Verlauf meiner Arbeit wurde klar, dass sich bei der Identifikation der Wiesen oft erhebliche Probleme ergaben. Durch Veränderungen in der landwirtschaftlichen Nutzung sind viele Pflanzenbestände nicht mehr eindeutig den bekannten Wiesentypen älterer syntaxonomischer Systeme zuordenbar. Hier lässt sich ein Bedarf an weiterer Forschung erkennen.
SE#PCFG: Semantically Enhanced PCFG for Password Analysis and Cracking
Creators: name: Wang, Yangde
name: Qiu, Weidong
name: Tang, Peng
name: Tian, Hao
name: Li, Shujun
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cryptography and Security (cs.CR)
subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Much research has been done on user-generated textual passwords. Surprisingly, semantic information in such passwords remain under-investigated, with passwords created by English- and/or Chinese-speaking users being more studied with limited semantics. This paper fills this gap by proposing a general framework based on semantically enhanced PCFG (probabilistic context-free grammars) named SE#PCFG. It allowed us to consider 43 types of semantic information, the richest set considered so far, for password analysis. Applying SE#PCFG to 17 large leaked password databases of user speaking four languages (English, Chinese, German and French), we demonstrate its usefulness and report a wide range of new insights about password semantics at different levels such as cross-website password correlations. Furthermore, based on SE#PCFG and a new systematic smoothing method, we proposed the Semantically Enhanced Password Cracking Architecture (SEPCA), and compared its performance against three SOTA (state-of-the-art) benchmarks in terms of the password coverage rate: two other PCFG variants and neural network. Our experimental results showed that SEPCA outperformed all the three benchmarks consistently and significantly across 52 test cases, by up to 21.53%, 52.55% and 7.86%, respectively, at the user-level (with duplicate passwords). At the level of unique passwords, SEPCA also beats the three counterparts by up to 43.83%, 94.11% and 11.16%, respectively.
Additional file 1 of Connections between body composition and dysregulation of islet α- and β-cells in type 2 diabetes
Creators: name: Miao, Jia-xi
name: Xu, Jia-ping
name: Wang, Rui
name: Xu, Yu-xian
name: Xu, Feng
name: Wang, Chun-hua
name: Yu, Chao
name: Zhang, Dong-mei
name: Su, Jian-bin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 1: Figure S1. Study flowchart.
Invariant systems of weighted representatives
Creators: name: Klyachko, Anton A.
name: Terekhov, Mikhail S.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Combinatorics (math.CO)
subject: Group Theory (math.GR)
subject: FOS: Mathematics

description: It is known that, if removing some $n$ edges from a graph $Γ$ destroys all subgraphs isomorphic to a given finite graph $K$, then all subgraphs isomorphic to $K$ can be destroyed by removing at most $|E(K)|\cdot n$ edges, which form a set invariant with respect to all automorphisms of $Γ$. We construct the first examples of (connected) graphs $K$ for which this estimate is not sharp. Our arguments are based on a ``weighted analogue'' of an earlier known estimate for the cost of symmetry.
description: 5 pages. A Russian version of this paper is at http://halgebra.math.msu.su/staff/klyachko/papers.htm . V2: minor corrections
On the regularization of the ill-posed logarithmic kernel integral equation of the first kind.
Creators: name: Bruckner, Gottfried
Publisher: name: Weierstrass Institute
Year: 1993
Subjects: subject: decomposition
subject: ill-posed logarithmic kernel integral equations
subject: ill-posed problem
subject: singular value decomposition
subject: parameter choice
subject: regularization method
subject: optimal convergence
subject: 65R30
subject: 65T05
subject: 65T10

description: The logarithmic kernel integral equation of the first kind is investigated as improperly posed problem considering its right-hand side as observed quantity in a suitable space with a weaker norm. The improperly posed problem is decomposed into a well-posed one, extensively studied in the literature (cf. e.g. [11], [13], [14]), and an ill-posed imbedding problem. For the ill-posed part a modified truncated singular value decomposition regularization method is proposed that allows an easily performable a-posteriori parameter choice. The whole problem is then solved by combining the regularization method with a numerical procedure from [13] for the well-posed part. Finally, an error estimate is given revealing the influence of the observation error on the approximation error of the numerical procedure. For a specification of the discretization parameter as a known function of the noise level only, the optimal convergence order is achieved.
Additional file 2 of Connections between body composition and dysregulation of islet α- and β-cells in type 2 diabetes
Creators: name: Miao, Jia-xi
name: Xu, Jia-ping
name: Wang, Rui
name: Xu, Yu-xian
name: Xu, Feng
name: Wang, Chun-hua
name: Yu, Chao
name: Zhang, Dong-mei
name: Su, Jian-bin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 2: Table S1. Pearson’s correlation of body composition with indicators of glucagon suppression in all patients with T2D.
Additional file 3 of Connections between body composition and dysregulation of islet α- and β-cells in type 2 diabetes
Creators: name: Miao, Jia-xi
name: Xu, Jia-ping
name: Wang, Rui
name: Xu, Yu-xian
name: Xu, Feng
name: Wang, Chun-hua
name: Yu, Chao
name: Zhang, Dong-mei
name: Su, Jian-bin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 3: Figure S2. Graphically displayed correlations between limb lean mass and indicators of glucagon suppression in all patients with T2D (Glucagon30min/0min: glucagon suppression at 30 min; Glucagon60min/0min: glucagon suppression at 60 min; Glucagon120min/0min: glucagon suppression at 120 min).
ACCORD Education stater pack_How to automate building permitting with BIM
Creators: name: Saar, Jaan
Publisher: name: Zenodo
Year: 2025

description: Content Description:

This training material serves as an introductory educational package, offering a comprehensive overview and key references on BIM-based permitting. It explores the essential aspects of the BIM permitting process by addressing the Why, What, and How. The content highlights the benefits of BIM-based permitting, introduces openBIM standards, the processes of regulatory review, rule-checking, and automation. It also explains how to interpret rules into machine-readable formats and provides insights into available software tools. The material concludes with a compelling call to action, encouraging the adoption and implementation of BIM-based permitting to advance efficiency and innovation in the construction industry. 

 

Target groups:

 This training material targets Municipalities and governments but is also suitable to any professional willing to understand the basics of BIM-base building permitting process. 

 

Learning objectives: 

Knowledge of various maturity levels in the BIM-based permitting process and their significance, knowledge on openBIM its principles,

Understanding of the current challenges in building permitting, understanding the benefits in streamlining workflows and improving efficiency with BIM-based process, understanding the openBIM advantages for interoperability and collaboration.

Awareness of key standard & tools such as IFC (Industry Foundation Classes), IDS (Information Delivery Specification), bSDD (buildingSMART Data Dictionary), BCF (BIM Collaboration Format).

 Author: Jaan Saar, Chief Evangelist at Future Insights
Additional file 4 of Connections between body composition and dysregulation of islet α- and β-cells in type 2 diabetes
Creators: name: Miao, Jia-xi
name: Xu, Jia-ping
name: Wang, Rui
name: Xu, Yu-xian
name: Xu, Feng
name: Wang, Chun-hua
name: Yu, Chao
name: Zhang, Dong-mei
name: Su, Jian-bin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 4: Table S2. Pearson’s correlation of body composition with islet α-cell and β-cell functions in men with T2D (n = 414).
Supplemental Material - Similarity as a safe haven: Similarity leads to satisfaction in prevention focus
Creators: name: Cheon, Jeong Eun
name: Kim, Young-Hoon
Publisher: name: SAGE Journals
Year: 2023
Subjects: Communication and Media Studies not elsewhere classified
Psychology not elsewhere classified

description: Supplemental Material for Similarity as a safe haven: Similarity leads to satisfaction in prevention focus by Jeong Eun Cheon and Young-Hoon Kim in Journal of Social and Personal Relationships
title: Evaluierung der Ökostrominvestitionen der letzten Jahre mit fallspezifischen Interviews bei den Anlageninvestoren
Creators: name: Kravarik, Magdalena
Year: 2008

description: Die vorliegende Diplomarbeit wurde von der E-Control am Lehrstuhl für Energie- und Umweltmanagement des Betriebswirtschaftszentrums Brünnerstraße ausgeschrieben und im Oktober 2007 an die Autorin vergeben. Zielsetzung war es eine möglichst aktuelle Bestandsaufnahme der Betriebserfahrungen und wirtschaftlichen Rahmenbedingungen für die Ökostromtechnologien Windkraft, Biomasse flüssig und fest sowie Biogas zu erstellen. Dies wurde im Rahmen einer qualitativen Marktforschung durchgeführt. Insgesamt wurden 8 Interviews mit Anlagenbetreibern der oben genannten Sparten geführt, um mehr über deren Erfahrungen mit ihren Ökostromanlagen sowie die wirtschaftliche Situation zu erfahren.
sj-docx-1-anp-10.1177_00048674231207583 – Supplemental material for ‘E koekoe te Tūī, e ketekete te Kākā, e kuku te Kererū, The Tūī chatters, the Kākā cackles, and the Kererū coos’: Insights into explanatory factors, treatment experiences and recovery for Māori with eating disorders – A qualitative study
Creators: name: Clark, Mau Te Rangimarie
name: Manuel, Jenni
name: Lacey, Cameron
name: Pitama, Suzanne
name: Cunningham, Ruth
name: Jordan, Jennifer
Publisher: name: SAGE Journals
Year: 2023
Subjects: Psychology not elsewhere classified
Psychiatry (incl. Psychotherapy)
Neuroscience

description: Supplemental material, sj-docx-1-anp-10.1177_00048674231207583 for ‘E koekoe te Tūī, e ketekete te Kākā, e kuku te Kererū, The Tūī chatters, the Kākā cackles, and the Kererū coos’: Insights into explanatory factors, treatment experiences and recovery for Māori with eating disorders – A qualitative study by Mau Te Rangimarie Clark, Jenni Manuel, Cameron Lacey, Suzanne Pitama, Ruth Cunningham and Jennifer Jordan in Australian & New Zealand Journal of Psychiatry
sj-docx-2-anp-10.1177_00048674231207583 – Supplemental material for ‘E koekoe te Tūī, e ketekete te Kākā, e kuku te Kererū, The Tūī chatters, the Kākā cackles, and the Kererū coos’: Insights into explanatory factors, treatment experiences and recovery for Māori with eating disorders – A qualitative study
Creators: name: Clark, Mau Te Rangimarie
name: Manuel, Jenni
name: Lacey, Cameron
name: Pitama, Suzanne
name: Cunningham, Ruth
name: Jordan, Jennifer
Publisher: name: SAGE Journals
Year: 2023
Subjects: Psychology not elsewhere classified
Psychiatry (incl. Psychotherapy)
Neuroscience

description: Supplemental material, sj-docx-2-anp-10.1177_00048674231207583 for ‘E koekoe te Tūī, e ketekete te Kākā, e kuku te Kererū, The Tūī chatters, the Kākā cackles, and the Kererū coos’: Insights into explanatory factors, treatment experiences and recovery for Māori with eating disorders – A qualitative study by Mau Te Rangimarie Clark, Jenni Manuel, Cameron Lacey, Suzanne Pitama, Ruth Cunningham and Jennifer Jordan in Australian & New Zealand Journal of Psychiatry
Additional file 5 of Connections between body composition and dysregulation of islet α- and β-cells in type 2 diabetes
Creators: name: Miao, Jia-xi
name: Xu, Jia-ping
name: Wang, Rui
name: Xu, Yu-xian
name: Xu, Feng
name: Wang, Chun-hua
name: Yu, Chao
name: Zhang, Dong-mei
name: Su, Jian-bin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 5: Table S3. Pearson’s correlation of body composition with islet α- and β-cell functions in women with T2D (n = 315).
sj-docx-3-his-10.1177_11786329231212122 – Supplemental material for High Levels of Satisfaction Among Hearing Aid Users in a Pilot Study for Sustainable Low-Cost Auditory Rehabilitation Services in Samoa
Creators: name: Kaspar, Annette
name: Newall, John
name: Pifeleti, Sione
name: Hunkin, Galumalemana
Publisher: name: SAGE Journals
Year: 2023
Subjects: Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-docx-3-his-10.1177_11786329231212122 for High Levels of Satisfaction Among Hearing Aid Users in a Pilot Study for Sustainable Low-Cost Auditory Rehabilitation Services in Samoa by Annette Kaspar, John Newall, Sione Pifeleti and Galumalemana Hunkin in Health Services Insights
On the D-module of an isolated singularity
Creators: name: Bitoun, Thomas
Publisher: name: arXiv
Year: 2023
Subjects: subject: Algebraic Geometry (math.AG)
subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics

description: Let Z be the germ of a complex hypersurface isolated singularity of equation f, with Z at least of dimension 2. We consider the family of analytic D-modules generated by the powers of 1/f and describe it in terms of the pole order filtration on the de Rham cohomology of the complement of {f=0} in the neighborhood of the singularity.
description: Final version. Accepted for publication in Algebra & Number Theory
Additional file 6 of Connections between body composition and dysregulation of islet α- and β-cells in type 2 diabetes
Creators: name: Miao, Jia-xi
name: Xu, Jia-ping
name: Wang, Rui
name: Xu, Yu-xian
name: Xu, Feng
name: Wang, Chun-hua
name: Yu, Chao
name: Zhang, Dong-mei
name: Su, Jian-bin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 6: Table S4. Impact of body composition on outcomes of islet α- and β-cell functions according to multivariate linear regression analysis in men with T2D (n = 414).