cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Covalent Modifications of Histone H3K9 Promote Binding of CHD3
Creators: name: Gatchalian, Jovylyn
name: Tencer, Adam H.
name: Zhang, Yi
name: Bridgers, Joseph B.
name: Strahl, Brian D.
name: Kono, Hidetoshi
name: Sims, Jennifer K.
name: Ikebe, Jinzen
name: Darcy, Michael A.
name: Li, Wei
name: Poirier, Michael G.
name: Hayes, Jeffrey J.
name: Wade, Paul A.
name: Allen, Hillary F.
name: Di, Luo
name: Wang, Xiaodong
name: Kutateladze, Tatiana G.
name: Cox, Khan L.
name: Lyu, Jie
name: Gibson, Matthew D.
name: Weaver, Tyler M.
name: Musselman, Catherine A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Chromatin remodeling is required for genome function and is facilitated by ATP-dependent complexes, such as nucleosome remodeling and deacetylase (NuRD). Among its core components is the chromodomain helicase DNA binding protein 3 (CHD3) whose functional significance is not well established. Here, we show that CHD3 co-localizes with the other NuRD subunits, including HDAC1, near the H3K9ac-enriched promoters of the NuRD target genes. The tandem PHD fingers of CHD3 bind histone H3 tails and posttranslational modifications that increase hydrophobicity of H3K9-methylation or acetylation (H3K9me3 or H3K9ac)-enhance this interaction. Binding of CHD3 PHDs promotes H3K9Cme3-nucleosome unwrapping in vitro and perturbs the pericentric heterochromatin structure in vivo. Methylation or acetylation of H3K9 uniquely alleviates the intra-nucleosomal interaction of histone H3 tails, increasing H3K9 accessibility. Collectively, our data suggest that the targeting of covalently modified H3K9 by CHD3 might be essential in diverse functions of NuRD.
Semiparametric GEE analysis in partially linear single-index models for longitudinal data
Creators: name: Chen, Jia
name: Li, Degui
name: Liang, Hua
name: Wang, Suojin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: In this article, we study a partially linear single-index model for longitudinal data under a general framework which includes both the sparse and dense longitudinal data cases. A semiparametric estimation method based on a combination of the local linear smoothing and generalized estimation equations (GEE) is introduced to estimate the two parameter vectors as well as the unknown link function. Under some mild conditions, we derive the asymptotic properties of the proposed parametric and nonparametric estimators in different scenarios, from which we find that the convergence rates and asymptotic variances of the proposed estimators for sparse longitudinal data would be substantially different from those for dense longitudinal data. We also discuss the estimation of the covariance (or weight) matrices involved in the semiparametric GEE method. Furthermore, we provide some numerical studies including Monte Carlo simulation and an empirical application to illustrate our methodology and theory.
description: Published at http://dx.doi.org/10.1214/15-AOS1320 in the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Leopoldo Pasqui a Ubaldino Peruzzi (22 febbraio 1852)
Creators: name: Pasqui, Leonardo
name: Peruzzi, Ubaldino
Publisher: name: Zenodo
Year: 2023
Subjects: Accademia dei Georgofili
Peruzzi, Ubaldino
Pasqui, Leopoldo
Lettera
Carteggio
Correspondence
Letter
1852

description: Lettera di Leopoldo Pasqui a Ubaldino Peruzzi del 22 febbraio 1852. Segnatura dell’unità documentale: Archivio storico dell’Accademia dei Georgofili, Carteggio, Busta 31, 2683. Natura: manoscritto. Consistenza: cc. 4
description: Digitalizzato come parte della Mostra virtuale: Ubaldino Peruzzi : un percorso in rete : in occasione del bicentenario della nascita. https://www.georgofili.it/contenuti/ubaldino-peruzzi-un-percorso-in-rete/17485
title: Reverse MRA: a retrospective review of neuroimaging at the Ottawa hospital
Creators: name: Glikstein, Rafael
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: Vascular
subject: Anatomy
subject: MR-Angiography
subject: Diagnostic procedure
subject: Aneurysms
subject: Image verification

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: •Review the MRA sequences performed in 3T magnet by inverting the signal of the vessels and the background. •Determine if this method of imaging enables greater visibility of the small caliber intracranial arteries. •Enhancing the viewer’s...
NLO QCD and electroweak corrections to $Z+γ$ production with leptonic Z-boson decays
Creators: name: Denner, Ansgar
name: Dittmaier, Stefan
name: Hecht, Markus
name: Pasold, Christian
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The next-to-leading-order electroweak corrections to $pp\to l^+l^-/\barνν+γ+X$ production, including all off-shell effects of intermediate Z bosons in the complex-mass scheme, are calculated for LHC energies, revealing the typically expected large corrections of tens of percent in the TeV range. Contributions from quark-photon and photon-photon initial states are taken into account as well, but their impact is found to be moderate or small. Moreover, the known next-to-leading-order QCD corrections are reproduced. In order to separate hard photons from jets, both a quark-to-photon fragmentation function á la Glover/Morgan and Frixione's cone isolation are employed. The calculation is available in the form of Monte Carlo programs allowing for the evaluation of arbitrary differential cross sections. Predictions for integrated cross sections are presented for the LHC at 7 TeV, 8 TeV, and 14 TeV, and differential distributions are discussed at 14 TeV for bare muons and dressed leptons. Finally, we consider the impact of anomalous $ZZγ$ and $Zγγ$ couplings.
description: 33 pages latex, 20 figures, remarks on theoretical uncertainties added, version to appear in JHEP. arXiv admin note: text overlap with arXiv:1412.7421
title: Comparison of subjective breast density categorisation vs VOLPARA software
Creators: name: Alomaim, Wijdan
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Breast
subject: Mammography
subject: Screening
subject: Quality assurance

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The female breast on mammographic images appears in grey scales relative to the amount of fat, connective and glandular tissues [1]. Fat is radiolucent and appears dark on mammographic images, whereas the fibroglandular tissue appears as a bright...
title: Multidetector CT of pancreatic ductal adenocarcinoma: effect of tube-voltage and iodine-load on tumour conspicuity, vessel involvement and image quality
Creators: name: Kartalis, Nikolaos
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Pancreas
subject: CT
subject: CT-High Resolution
subject: CT-Quantitative
subject: Computer Applications-Detection, diagnosis
subject: Contrast agent-intravenous
subject: Technical aspects
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Pancreatic ductal adenocarcinoma (PDAC), although rare, is the fourth leading cause of cancer-related deaths worldwide [1]. Overall five-year survival does not exceed 5% and only following surgery with curative intent can it reach up to 20% [2]. It...
Differential Regulation of Lipoprotein and Hepatitis C Virus Secretion by Rab1b
Creators: name: Rice, Charles M.
name: Wu, Xianfang
name: Simon, Sanford M.
name: Dao Thi, Viet Loan
name: Belote, Rachel L.
name: Andreo, Ursula
name: Spitz-Becker, Gabriella S.
name: Gleason, Caroline E.
name: Itano, Michelle S.
name: Takacs, Constantin N.
name: Hedin, Brenna R.
name: Scull, Margaret A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Secretory cells produce diverse cargoes, yet how they regulate concomitant secretory traffic remains insufficiently explored. Rab GTPases control intracellular vesicular transport. To map secretion pathways, we generated a library of lentivirus-expressed dominant-negative Rab mutants and used it in a large-scale screen to identify regulators of hepatic lipoprotein secretion. We identified several candidate pathways, including those mediated by Rab11 and Rab8. Surprisingly, inhibition of Rab1b, the major regulator of transport from the endoplasmic reticulum to the Golgi, differently affected the secretion of the very-low-density lipoprotein components ApoE and ApoB100, despite their final association on mature secreted lipoprotein particles. Since hepatitis C virus (HCV) incorporates ApoE and ApoB100 into its virus particle, we also investigated infectious HCV secretion and show that its regulation by Rab1b mirrors that of ApoB100. These observations reveal differential regulation of hepatocyte secretion by Rab1b and advance our understanding of lipoprotein assembly and lipoprotein and HCV secretion.
title: Reliability and time effectivity of an assisted bone reading software for the analysis of CT trauma cases
Creators: name: Anton, Susanne
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Emergency
subject: Trauma
subject: Musculoskeletal bone
subject: CT
subject: Computer Applications-Detection, diagnosis
subject: Trauma

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Whole body computed tomography is a standardized examination of trauma patients [1]. It is used for the rapid diagnosis of acute life-threatening diseases. A quick and correct radiological diagnosis is of great interest for prompt and timely...
title: Distinguishing high-flow from low-flow vascular malformations using maximum intensity projection images in dynamic magnetic resonance angiography
Creators: name: Majewska, Natalia
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Vascular
subject: MR-Angiography
subject: MR
subject: Embolisation

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: There are multiple classifications for vascular abnormalities. The newest is “ISSVA classification for vascular anomalies” (Table 1) which is based on the founding biological investigation of Mulliken and Glowacki published in 1982. More...
title: Increased reproducibility of semiautomatic 3D-segmentation over 2D-measurements for quantification of specific iodine uptake of hepatic colorectal metastases in dual-energy CT
Creators: name: Winter, Katharina
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Liver
subject: CT
subject: CT-Quantitative
subject: Computer Applications-3D
subject: Computer Applications-General
subject: Staging
subject: Metastases
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: With its capability to quantify absolute iodine concentrations, Dual-Energy CT (DECT) promises to add considerable diagnostic information in the field of abdominal oncologic imaging (Agrawal et al., 2014). Iodine maps contain quantifiable...
Rapid spatial equilibration of a particle in a box
Creators: name: Malabarba, Artur S. L.
name: Linden, Noah
name: Short, Anthony J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the equilibration behaviour of a quantum particle in a one-dimensional box, with respect to a coarse grained position measurement (whether it lies in a certain spatial window or not). We show that equilibration in this context indeed takes place and does so very rapidly, in a time comparable to the time for the initial wave packet to reach the edges of the box. We also show that, for this situation, the equilibration behaviour is relatively insensitive to the precise choice of position measurements or initial condition.
description: 5 pages and 5 figures in main text
Perceptions of fairness in default effect interventions Study 1
Creators: name: Michaelsen, Patrik
name: Nyström, Lina
name: Luke, Timothy
name: Johansson, Lars-Olof
name: Hedesström, Martin
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Behavioral Economics
subject: Experimental Analysis of Behavior
subject: Quantitative Psychology
subject: Cognitive Psychology
subject: Economics
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: This is a preregistration for Study 1.
title: Incidence and mortality of spontaneous subarachnoid haemorrhage in Martinique from 2007 to 2013
Creators: name: SCHERTZ, Mathieu
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: Emergency
subject: Vascular
subject: CT-Angiography
subject: CT
subject: Catheter arteriography
subject: Arterial access
subject: Socio-economic issues
subject: Aneurysms
subject: Epidemiology
subject: Haemorrhage

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Incidence of subarachnoid hemorrhages (SAH) vary wildly across the world and seems to be low in Central and South America 1 . Martinique is a small French island in the Caribbean Sea (Fig 1) well fitted for epidemiological study. The objective of...
Alteration to preregistration intensive parenting norms
Creators: name: Meeussen, Loes
name: Block, Katharina
name: Schmader, Toni
name: Van Grootel, Sanne
name: olsson, maria
name: Martiny, Sarah
name: Schuster, Carolin
name: Wee, Sheila
name: Sun, Molly
name: Croft, Alyssa
name: van Laar, Colette
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: Alteration to preregistration on Dec 2nd 2019
Analysis of a slow-fast system near a cusp singularity
Creators: name: Jardón-Kojakhmetov, H.
name: Broer, Henk W.
name: Roussarie, R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: This paper studies a slow-fast system whose principal characteristic is that the slow manifold is given by the critical set of the cusp catastrophe. Our analysis consists of two main parts: first, we recall a formal normal form suitable for systems as the one studied here; afterwards, taking advantage of this normal form, we investigate the transition near the cusp singularity by means of the blow up technique. Our contribution relies heavily in the usage of normal form theory, allowing us to refine previous results.
title: The outcome of fMRI language mapping is affected by patient fatigue
Creators: name: Kiss, Máté
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: CNS
subject: MR-Functional imaging
subject: MR
subject: Outcomes analysis
subject: Image verification

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Mapping the eloquent areas and/or determining language lateralization is very important for presurgical mapping, hence mapping the language/speech network is one of the most important usage of clinical functional MRI (fMRI) [1-3]. Choosing the...
title: Subclinical pulmonary tuberculosis and airway obstruction: correlation of HRCT findings with pulmonary function test and immunologic diagnostic test of tuberculosis
Creators: name: Lee, Do Hyung
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Lung
subject: CT-High Resolution
subject: CT-Quantitative
subject: Digital radiography
subject: Statistics
subject: Computer Applications-3D
subject: Infection
subject: Chronic obstructive airways disease

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The complication of advanced tuberculosis(TB) or partially treated TB can result in airflow obstruction. It is not clear that the relationship of subclinical pulmonary tuberculosis(SPTB) with airflow obstruction. We studied the relationship of...
DNA Ligase IV Guides End-Processing Choice during Nonhomologous End Joining
Creators: name: Rothenberg, Eli
name: Small, George W.
name: Chang, Howard H.
name: Watanabe, Go
name: Reid, Dylan A.
name: Conlin, Michael P.
name: Ramsden, Dale A.
name: Lieber, Michael R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Nonhomologous end joining (NHEJ) must adapt to diverse end structures during repair of chromosome breaks. Here, we investigate the mechanistic basis for this flexibility. DNA ends are aligned in a paired-end complex (PEC) by Ku, XLF, XRCC4, and DNA ligase IV (LIG4); we show by single-molecule analysis how terminal mispairs lead to mobilization of ends within PECs and consequent sampling of more end-alignment configurations. This remodeling is essential for direct ligation of damaged and mispaired ends during cellular NHEJ, since remodeling and ligation of such ends both require a LIG4-specific structural motif, insert1. Insert1 is also required for PEC remodeling that enables nucleolytic processing when end structures block direct ligation. Accordingly, cells expressing LIG4 lacking insert1 are sensitive to ionizing radiation. Cellular NHEJ of diverse ends thus identifies the steps necessary for repair through LIG4-mediated sensing of differences in end structure and consequent dynamic remodeling of aligned ends.
title: Chest adipose tissue distribution in patients with morbid obesity
Creators: name: Lemanowicz, Adam
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Soft tissues / Skin
subject: CT
subject: Screening
subject: Eating disorders

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Obesity, according to the WHO definition, is a pathological accumulation of fat in the adipose tissue, beyond physiological needs and adaptability, which may lead to adverse health effects. The worldwide prevalence of obesity more than doubled...
Psychopathy facets and types of crime
Creators: name: McCarthy, Alora
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Clinical Psychology
subject: Criminology
subject: FOS: Law
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Sociology
subject: FOS: Sociology
subject: crime
subject: facet
subject: offense
subject: PCL-R
subject: psychopathy
subject: Psychopathy Checklist

description: This study will explore how facets on the Psychopathy Checklist Revised (PCL-R; Hare, 2003) relate to types of crimes committed.
title: Diffusion kurtosis imaging in differentiation of WHO Grade-2 gliomas
Creators: name: Tonoyan, Aram
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: MR-Diffusion/Perfusion
subject: Diagnostic procedure
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Gliomas are the most common primary brain tumors in adults, which encompass tumors of different etiology and malignancy. The 2007 World Health Organization (WHO) classification of tumors of the central nervous system (CNS) helps to predict...
A scoping review of respirator literature
Creators: name: Maspero, Cinzia
name: Boccalari, Elisa
name: del Rosso, Ettore
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Dentistry
subject: FOS: Clinical medicine

description: This scoping review aims to assess whether, in the current COVID-19 pandemic situation,while wearing FFP2 respirators for many hours, health care workers (in particular dentists) experience discomfort, exertion, headaches, breathing difficulties and other side effects along with drop in job performances.
title: MRI-MRCP characteristics of autoimmune pancreatitis
Creators: name: Avesani, Giacomo
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Pancreas
subject: MR
subject: Contrast agent-intravenous

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Up to now the studies which evaluated the parenchymal alterations and ductal involvement of autoimmune pancreatitis (AIP) were conducted on a restricted population. The purpose of this study is to better delineate the MRI-MRCP findings in a large...
$C^*$-algebras associated to Boolean dynamical systems
Creators: name: Carlsen, Toke Meier
name: Ortega, Eduard
name: Pardo, Enrique
Publisher: name: arXiv
Year: 2015
Subjects: subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 46L05, 46L55

description: The goal of these notes is to present the C*-algebra $C^*(B,L,θ)$ of a Boolean dynamical system $(B,L,θ)$, that generalizes the $C^*$-algebra associated to Labelled graphs introduced by Bates and Pask, and to determine its simplicity, its gauge invariant ideals, as well as compute its K-Theory
HNE : enjeux disciplinaires
Creators: name: Baron, Georges-Louis
name: Loffreda, Magali
Publisher: name: Zenodo
Year: 2023
Subjects: GTnum HN_education
Disciplines scolaires
Projets de recherche

description: Les travaux menés au sein du GTnum GIS 2IF "Humanités numériques entre éducation et formation" #HN_éducation ont visé à interroger la pertinence de la notion d'humanités numériques dans un but de clarification, de mutualisation et d’amélioration des apprentissages et à recenser les pratiques d’enseignement dans ce champ. Groupes thématiques numériques de la Direction du numérique pour l’éducation (Ministère de l'Éducation nationale et de la Jeunesse) 2020-2022. Dans ce bulletin de veille, Georges-Louis Baron et Magali Loffreda rendent compte de la manière dont les Humanités numériques ont été prises en considération dans les projets de recherche qui concernent l'enseignement primaire et secondaire, et au sein des disciplines scolaires.
Extensive Homeostatic T Cell Phenotypic Variation within the Collaborative Cross
Creators: name: Mooney, Michael
name: Graham, Jessica B.
name: Choonoo, Gabrielle
name: Ferris, Martin T.
name: Jeng, Sophia
name: Swarts, Jessica L.
name: McWeeney, Shannon
name: Miller, Darla R.
name: Lund, Jennifer M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The Collaborative Cross (CC) is a panel of reproducible recombinant inbred mouse strains with high levels of standing genetic variation, affording an unprecedented opportunity to perform experiments in a small animal model containing controlled genetic diversity while allowing for genetic replicates. Here, we advance the utility of this unique mouse resource for immunology research because it allows for both examination and genetic dissection of mechanisms behind adaptive immune states in mice with distinct and defined genetic makeups. This approach is based on quantitative trait locus mapping: identifying genetically variant genome regions associated with phenotypic variance in traits of interest. Furthermore, the CC can be utilized for mouse model development; distinct strains have unique immunophenotypes and immune properties, making them suitable for research on particular diseases and infections. Here, we describe variations in cellular immune phenotypes across F1 crosses of CC strains and reveal quantitative trait loci responsible for several immune phenotypes.
title: Θραυστο-μηχανική συμπεριφορά κεραμικών υλικών ενισχυμένων με μεταλλικά σωματίδια
Creators: name: Ρωσιος Κωνσταντινος
Publisher: name: Technical University of Crete
Year: 2022

description: Η παρούσα διπλωματική εργασία κάνει μια βιβλιογραφική ανασκόπηση της μηχανικής συμπεριφοράς των σύνθετων υλικών με κεραμική μήτρα και μεταλλική ενίσχυση. Μελετώνται οι ελαστικές μηχανικές τους ιδιότητες αλλά και οι τελικές τους ιδιότητες (κατά τη θραύση/αστοχία τους). Πειραματικά δεδομένα ελαστικών ιδιοτήτων από τη βιβλιογραφία συγκρίνονται με μοντέλα που αναπτύχθηκαν για να περιγράψουν/προβλέψουν το μέτρο ελαστικότητας των σύνθετων αυτών υλικών. Η μεταλλική ενίσχυση οδηγεί σε σύνθετα υλικά με κεραμική μήτρα τα οποία είναι λιγότερο ευπαθή σε ψαθυρή θραύση λόγω διάδοσης ρωγμής. Η βελτίωση επιτυγχάνεται με την ενεργοποίηση μιας σειράς μηχανισμών βελτίωσης της αντοχής και της δυσθραυστότητας των συνθέτων αυτών υλικών. Οι μηχανισμοί αυτοί αναλύονται και κρίνονται επίσης στη παρούσα διπλωματική εργασία. Έμφαση δίνεται στα σύνθετα υλικά με μήτρα Al2O3 (αλουμίνας) ενισχυμένης με μεταλλικά εγκλείσματα.
description: This thesis reviews the literature of the mechanical behaviour of metal particle-reinforced ceramics. The elastic properties (stiffness) and the fracture mechanics and ultimate properties of these materials (strength and toughness) are reviewed. Available experimental data are compared with models that have been developed to predict the elasticity modulus of the composite materials. Reinforcing ceramics with ductile metallic particles is found to result in composites that are less susceptible to brittle fracture caused by a propagating crack. The reinforcing effect is found to be accomplished by the activation of various toughening mechanisms in the material that are analysed and discussed. The augmented mechanical properties (strength and fracture toughness) for these ceramic matrix composites are evaluated in the present thesis.
The rhythm of binocular rivalry: control experiment
Creators: name: Torralba Cuello, Mireia
name: Soto-Faraco, Salvador
name: Drew, Alice
name: Fazekas, László
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Cognitive Neuroscience
subject: Life Sciences
subject: Neuroscience and Neurobiology
subject: Binocular Rivalry
subject: Entrainment

description: This experiment is part of the project on the IAF-NAR correlation. The aims and hypotheses of the study can be found at the pre-registration files: • Individual alpha frequency as a marker for binocular rivalry dynamics: https://osf.io/n5c8g/ • The rhythm of binocular rivalry: https://osf.io/w8m4q/
Tunneling-induced transparency and Autler-Townes splitting in a triple quantum dot
Creators: name: Luo, Xiao-Qing
name: Li, Zeng-Zhao
name: Jing, Jun
name: Li, Tie-Fu
name: Yu, Ting
name: You, J. Q.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We theoretically investigate the tunneling-induced transparency (TIT) and the Autler-Townes (AT) doublet and triplet in a triple-quantum-dot system. For the resonant tunneling case, we show that the TIT induces a transparency dip in a weak-tunneling regime and no anticrossing occurs in the eigenenergies of the system Hamiltonian. However, in a strong-tunneling regime, we show that the TIT evolves to the AT splitting, which results in a well-resolved doublet and double anticrossings. For the off-resonance case, we demonstrate that, in the weak-tunneling regime, the double TIT is realized with a new detuning-dependent dip, where the anticrossing is also absent. In the strong-tunneling regime, the AT triplet is realized with triple anticrossings and a wide detuning-dependent transparency window by manipulating one of the energy-level detunings. Our results can be applied to quantum measurement and quantum-optics devices in solid systems.
description: 8 pages, 5 figures
Observation of top quark pairs produced in association with a vector boson in pp collisions at sqrt(s) = 8 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Measurements of the cross sections for top quark pairs produced in association with a W or Z boson are presented, using 8 TeV pp collision data corresponding to an integrated luminosity of 19.5 inverse femtobarns, collected by the CMS experiment at the LHC. Final states are selected in which the associated W boson decays to a charged lepton and a neutrino or the Z boson decays to two charged leptons. Signal events are identified by matching reconstructed objects in the detector to specific final state particles from ttW or ttZ decays. The ttW cross section is measured to be 382 +117 -102 fb with a significance of 4.8 standard deviations from the background-only hypothesis. The ttZ cross section is measured to be 242 +65 -55 fb with a significance of 6.4 standard deviations from the background-only hypothesis. These measurements are used to set bounds on five anomalous dimension-six operators that would affect the ttW and ttZ cross sections.
description: Replaced with published version. Added journal reference and DOI
Mapping the Research Landscape of the Special Characteristics of Head Mounted Display Virtual Reality in Comparison to Established Technology Such as Monitors or C.A.V.E's.–A Systematic Scoping Review
Creators: name: Hepperle, Daniel
name: Wölfel, Matthias
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Physical Sciences and Mathematics
subject: Graphics and Human Computer Interfaces
subject: Computer Sciences
subject: Social and Behavioral Sciences

description: Systematic Literature Review on current quantitative research regarding differences between real world and HMD VR; between 2D (Monitors) and HMD VR; between C.A.V.E. and HDM VR;
H3K36 Methylation Regulates Nutrient Stress Response in  Saccharomyces cerevisiae  by Enforcing Transcriptional Fidelity
Creators: name: Strahl, Brian D.
name: McDaniel, Stephen L.
name: Hepperla, Austin J.
name: Davis, Ian J.
name: Dronamraju, Raghuvar
name: Adams, Alexander T.
name: Huang, Jie
name: Kulkarni, Vidyadhar G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Set2-mediated histone methylation at H3K36 regulates diverse activities, including DNA repair, mRNA splicing, and suppression of inappropriate (cryptic) transcription. Although failure of Set2 to suppress cryptic transcription has been linked to decreased lifespan, the extent to which cryptic transcription influences other cellular functions is poorly understood. Here, we uncover a role for H3K36 methylation in the regulation of the nutrient stress response pathway. We found that the transcriptional response to nutrient stress was dysregulated in SET2-deleted (set2Δ) cells and was correlated with genome-wide bi-directional cryptic transcription that originated from within gene bodies. Antisense transcripts arising from these cryptic events extended into the promoters of the genes from which they arose and were associated with decreased sense transcription under nutrient stress conditions. These results suggest that Set2-enforced transcriptional fidelity is critical to the proper regulation of inducible and highly regulated transcription programs.
title: Added value of 3D proton-density weighted images in diagnosis of intracranial arterial dissection
Creators: name: Lee, Won Kyung
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: MR
subject: Contrast agent-intravenous
subject: Venous access
subject: Dissection
subject: Dilatation
subject: Haemodynamics / Flow dynamics

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Introduction Cerebrovascular dissection can accompany various neurological events, including ischemic stroke or subarachnoid hemorrhage besides causing local symptoms such as headache. Over 80% of these neurological complications occur in the first...
title: Microwave ablation of large HCCs using a new device: a case series
Creators: name: Tarantino, Luciano
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Liver
subject: Ultrasound
subject: Ablation procedures
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Normal 0 14 false false false IT JA X-NONE The insertion inside the tumor tissue of a single device commercially available at the moment rarely obtain a necrosis area exceeding 3 .5 cm in transverse diameter. A straight cooled tip RF needle, can...
title: An investigation into the effectiveness of common cleaning wipes in removing infection control risks from radiographic cassettes
Creators: name: England, Andrew
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Professional issues
subject: Safety
subject: Infection

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Approximately 300,000 patients in England will acquire a healthcare associated infections (HCAIs) each year (National Institute of Health & Care Excellence, 2014). HCAIs can aggravate current conditions, delay recovery and seriously affect a...
title: Differentiation between high-grade gliomas and metastatic brain tumours using diffusion tensor imaging metrics
Creators: name: El-Morsy, Ahmad
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: CNS
subject: Neuroradiology brain
subject: Oncology
subject: MR
subject: MR-Functional imaging
subject: MR-Diffusion/Perfusion
subject: Diagnostic procedure
subject: Metastases
subject: Neoplasia

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: According to WHO 2007 classification glioblastoma and brain metastases are the most common brain neoplasms in adults (1) , and the radiological and clinical differentiation between these two neoplasms is very important to achieve good clinical...
title: Application of texture analysis based on ADC maps in discriminating different stages of rectal cancer
Creators: name: Liu, Liheng
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Colon
subject: Pelvis
subject: MR-Diffusion/Perfusion
subject: MR
subject: Staging
subject: Image guided radiotherapy

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Introduction In recent years, notable progress has been made in the management of rectal cancer. In particular, the use of neoadjuvant chemoradiotherapy (NAT) for locally advanced rectal carcinoma (stage T3-4 and/or N1-2) has been shown to be...
title: Positioning for a conventional skyline patella projection: evaluation of torso position and its relationship with eye lens and thyroid dose
Creators: name: England, Andrew
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Radioprotection / Radiation dose
subject: Conventional radiography
subject: Radiation safety

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: The skyline projection of the knee joint ( Fig 1 ) is a common reason for assessing the patello-femoral joint space, investigating the presence of patella subluxation and in evaluating other inflammatory and degenerative conditions...
Constraints on the neutrino parameters by future cosmological 21cm line and precise CMB polarization observations
Creators: name: Oyama, Yoshihiko
name: Kohri, Kazunori
name: Hazumi, Masashi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Observations of the 21 cm line radiation coming from the epoch of reionization have a great capacity to study the cosmological growth of the Universe. Also, CMB polarization produced by gravitational lensing has a large amount of information about the growth of matter fluctuations at late time. In this paper, we investigate their sensitivities to the impact of neutrino property on the growth of density fluctuations, such as the total neutrino mass, the effective number of neutrino species (extra radiation), and the neutrino mass hierarchy. We will show that by combining a precise CMB polarization observations such as Simons Array with a 21 cm line observation such as Square kilometer Array (SKA) phase 1 and a baryon acoustic oscillation observation (Dark Energy Spectroscopic Instrument:DESI) we can measure effects of non-zero neutrino mass on the growth of density fluctuation if the total neutrino mass is larger than 0.1eV. Additionally, the combinations can strongly improve errors of the bounds on the effective number of neutrino species sigma(N_nu) ~ 0.06-0.09 at 95 % C.L.. Finally, by using SKA phase 2, we can determine the neutrino mass hierarchy at 95 % C.L. if the total neutrino mass is similar to or smaller than 0.1 eV.
description: 60 pages, 13 figures in JCAP02 (2016) 008
Survey Materials and MPlus Syntax
Creators: name: Lizzio-Wilson, Morgana
name: Thomas, Emma
name: Louis, Winnifred
name: Wilcockson, Brittany
name: Amiot, Catherine
name: Moghaddam, Fathali
name: McGarty, Craig
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Collective action
subject: Collective action outcomes
subject: Conventional action
subject: Latent Profile Analysis
subject: Longitudinal
subject: Marriage equality
subject: Mixture Models
subject: Radical action
subject: Social Identity Model of Collective Action

description: This registration contains the verbatim survey materials and MPlus syntax for a longitudinal project examining reactions to collective action failure and success in the context of the Australian Marriage Equality Movement.
title: The role of MRI diffusion weighted images in assessment of benign and malignant hepatic focal lesions in non paediatric age group
Creators: name: Abdelsamie, Ahmed
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Liver
subject: MR-Diffusion/Perfusion
subject: MR
subject: MR-Diffusion/Perfusion
subject: Molecular imaging
subject: Neoplasia
subject: Tissue characterisation
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Introduction The liver is an organ in which various benign, malignant primary or secondary focal lesions can be detected. Hepatic focal lesions constitute a daily challenge in clinical setting and due to its high prevalence and the ever-increasing...
Human Shape Variation - An Efficient Implementation using Skeleton
Creators: name: Sengupta, Dhriti
name: Kundu, Merina
name: Dastidar, Jayati Ghosh
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: It is at times important to detect human presence automatically in secure environments. This needs a shape recognition algorithm that is robust, fast and has low error rates. The algorithm needs to process camera images quickly to detect any human in the range of vision, and generate alerts, especially if the object under scrutiny is moving in certain directions. We present here a simple, efficient and fast algorithm using skeletons of the images, and simple features like posture and length of the object.
Entanglement Temperature With Gauss-Bonnet Term
Creators: name: Pal, Shesansu Sekhar
name: Panda, Sudhakar
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We compute the entanglement temperature using the first law-like of thermodynamics, $ΔE=T_{ent} ΔS_{EE}$, up to Gauss-Bonnet term in the Jacobson-Myers entropy functional in any arbitrary spacetime dimension. The computation is done when the entangling region is the geometry of a slab. We also show that such a Gauss-Bonnet term, which becomes a total derivative, when the co-dimension two hypersurface is four dimensional, does not contribute to the finite term in the entanglement entropy. We observe that the Weyl-squared term does not contribute to the entanglement entropy. It is important to note that the calculations are performed when the entangling region is very small and the energy is calculated using the normal Hamiltonian.
description: 1+15 pages, v2: References added
title: Sports imaging in Baku: similarities and differences between the first European games and the London olympics
Creators: name: Remedios, Denis
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Musculoskeletal soft tissue
subject: Musculoskeletal joint
subject: Musculoskeletal bone
subject: Ultrasound
subject: MR
subject: CT
subject: Diagnostic procedure
subject: Athletic injuries
subject: Workforce

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Baku may be best known by some for Bond, BMW and Beluga caviar. Lying on the shores of the Caspian Sea, Baku the “windy city” combines the charm from the Ottoman Empire with state-of-the-art edifices such as the Flame Towers, fuelled by the...
MAP3K4 Controls the Chromatin Modifier HDAC6 during Trophoblast Stem Cell Epithelial-to-Mesenchymal Transition
Creators: name: Homayouni, Ramin
name: Roy, Sujoy
name: Abell, Amy N.
name: Zawistowski, Jon S.
name: Abell-Hart, Kayley
name: Mobley, Robert J.
name: Lutz, Kyla
name: Raghu, Deepthi
name: Duke, Lauren D.
name: Johnson, Gary L.
name: Gomez, Shawn M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The first epithelial-to-mesenchymal transition (EMT) occurs in trophoblast stem (TS) cells during implantation. Inactivation of the serine/threonine kinase MAP3K4 in TS cells (TSKI4 cells) induces an intermediate state of EMT, where cells retain stemness, lose epithelial markers, and gain mesenchymal characteristics. Investigation of relationships among MAP3K4 activity, stemness, and EMT in TS cells may reveal key regulators of EMT. Here, we show that MAP3K4 activity controls EMT through the ubiquitination and degradation of HDAC6. Loss of MAP3K4 activity in TSKI4 cells results in elevated HDAC6 expression and the deacetylation of cytoplasmic and nuclear targets. In the nucleus, HDAC6 deacetylates the promoters of tight junction genes, promoting the dissolution of tight junctions. Importantly, HDAC6 knockdown in TSKI4 cells restores epithelial features, including cell-cell adhesion and barrier formation. These data define a role for HDAC6 in regulating gene expression during transitions between epithelial and mesenchymal phenotypes.
Realizing Mathematics of Arrays Operations as Custom Architecture Hardware-Software Co-Design Solutions
Creators: name: GROUT, IAN
name: Mullin, Lenore
Publisher: name: University of Limerick
Year: 2023
Subjects: Information and computing sciences

description: In embedded electronic system applications being developed today, complex datasets are required to be obtained, processed, and communicated. These can be from various sources such as environmental sensors, still image cameras, and video cameras. Once obtained and stored in electronic memory, the data is accessed and processed using suitable mathematical algorithms. How the data are stored, accessed, processed, and communicated will impact on the cost to process the data. Such algorithms are traditionally implemented in software programs that run on a suitable processor. However, different approaches can be considered to create the digital system architecture that would consist of the memory, processing, and communications operations. When considering the mathematics at the centre of the design making processes, this leads to system architectures that can be optimized for the required algorithm or algorithms to realize. Mathematics of Arrays (MoA) is a class of operations that supports n-dimensional array computations using array shapes and indexing of values held within the array. In this article, the concept of MoA is considered for realization in software and hardware using Field Programmable Gate Array (FPGA) and Application Specific Integrated Circuit (ASIC) technologies. The realization of MoA algorithms will be developed along with the design choices that would be required to map a MoA algorithm to hardware, software or hardware-software co-designs.
Protection against High-Fat-Diet-Induced Obesity in MDM2 C305F  Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure
Creators: name: Kim, Tae-Hyung
name: Zhang, Yanping
name: Liu, Shijie
name: Franklin, Derek A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The RPL11-MDM2 interaction constitutes a p53 signaling pathway activated by deregulated ribosomal biosynthesis in response to stress. Mice bearing an MDM2C305F mutation that disrupts RPL11-MDM2 binding were analyzed on a high-fat diet (HFD). The Mdm2C305F/C305F mice, although phenotypically indistinguishable from WT mice when fed normal chow, demonstrated decreased fat accumulation along with improved insulin sensitivity and glucose tolerance after prolonged HFD feeding. We found that HFD increases expression of c-MYC and RPL11 in both WT and Mdm2C305F/C305F mice; however, p53 was only induced in WT but not in Mdm2C305F/C305F mice. Reduced p53 activity in HFD-fed Mdm2C305F/C305F mice resulted in higher levels of p53 down-regulated targets GLUT4 and SIRT1, leading to increased biosynthesis of NAD+, and increased energy expenditure. Our study reveals a role for the RPL11-MDM2-p53 pathway in fat storage during nutrient excess and suggests that targeting this pathway may be a potential treatment for obesity.
Telomere Recognition and Assembly Mechanism of Mammalian Shelterin
Creators: name: Kratz, Katja
name: Erdel, Fabian
name: Willcox, Smaranda
name: Griffith, Jack D.
name: de Lange, Titia
name: Greene, Eric C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Shelterin is a six-subunit protein complex that plays crucial roles in telomere length regulation, protection, and maintenance. Although several shelterin subunits have been studied in vitro, the biochemical properties of the fully assembled shelterin complex are not well defined. Here, we characterize shelterin using ensemble biochemical methods, electron microscopy, and single-molecule imaging to determine how shelterin recognizes and assembles onto telomeric repeats. We show that shelterin complexes can exist in solution and primarily locate telomeric DNA through a three-dimensional diffusive search. Shelterin can diffuse along non-telomeric DNA but is impeded by nucleosomes, arguing against extensive one-dimensional diffusion as a viable assembly mechanism. Our work supports a model in which individual shelterin complexes rapidly bind to telomeric repeats as independent functional units, which do not alter the DNA-binding mode of neighboring complexes but, rather, occupy telomeric DNA in a "beads on a string" configuration.