cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Estimation of anisotropic bending rigidities and spontaneous curvatures of crescent curvature-inducing proteins from tethered-vesicle experimental data
Creators: name: Noguchi, Hiroshi
name: Walani, Nikhil
name: Arroyo, Marino
Publisher: name: arXiv
Year: 2023
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: The Bin/amphiphysin/Rvs (BAR) superfamily proteins have a crescent binding domain and bend biomembranes along the domain axis. However, their anisotropic bending rigidities and spontaneous curvatures have not been experimentally determined. Here, we estimated these values from the bound protein densities on tethered vesicles using a mean-field theory of anisotropic bending energy and orientation-dependent excluded volume. The dependence curves of the protein density on the membrane curvature are fitted to the experimental data for the I-BAR and N-BAR domains reported by C. Prevost et al. Nat. Commun. 6, 8529 (2015) and F.-C. Tsai et al. Soft Matter 17, 4254 (2021), respectively. For the I-BAR domain, all three density curves of different chemical potentials exhibit excellent fits with a single parameter set of anisotropic bending energy. When the classical isotropic bending energy is used instead, one of the curves can be fitted well, but the others exhibit large deviations. In contrast, for the N-BAR domain, two curves are not well-fitted simultaneously using the anisotropic model, although it is significantly improved compared to the isotropic model. This deviation likely suggests a cluster formation of the N-BAR domains.
description: 12 pages, 15 figures
Vestígios da prática cerimonial judaica no Cante o canto colectivo do Baixo Alentejo
Creators: name: Weffort, Alexandre Branco
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2013

description: Trata-se de uma dimensão da cultura portuguesa em muitos aspectos ignorada. Está ainda por conhece ra influência das vivências cripto-judaicas na conformação de determinadas práticas tradicionais populares,mesmo naquelas que foram absorvidas por práticas de âmbito religioso e integradas na cultura cristã numa perspectiva até litúrgica (ou que se afastaram desse prisma inicial,no sentido de uma expressão da vida profana).
description: Revista Lusófona de Ciência das Religiões, n. 16-17: Parte I: Para a História do Arquivo Secreto do Vaticano
Arbuscular mycorrhizal fungi enhance monoterpene production in red clover (Trifolium pratense L.): a potential tool for pest control
Creators: name: Medina, Cristian
name: Mutis, Ana
name: Bardehle, Leonardo
name: Hormazabal, Emilio
name: Borie, Fernando
name: Aguilera, Paula
name: Ortega, Fernando
name: Quiroz, Andrés
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Ecology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: The possibility of modifying terpene production in plants is a defensive strategy that has been studied in conjunction with their biosynthetic pathways. A biotic factor such as Arbuscular Mycorrhizal Fungi (AMF) could modify terpene production in Trifolium pratense L. In this work, the enzymatic production of monoterpenes in Superqueli INIA cultivar with two AMF was evaluated via HeadSpace-Gas Chromatography (HS-GC). A significant increase of (S)-limonene was found in plants inoculated with Claroideoglomus claroideum as well as with the AMF mix (genera Scutellospora, Acaulospora and Glomus). Moreover, significant increases in other monoterpenes such as (-)-β-pinene, myrcene, linalool, were observed. Results showed higher monoterpene production capacities in the Superqueli-INIA cultivar, suggesting the participation of monoterpene synthases (MTS). The significant rise of (S)-limonene in red clover plants inoculated with AMF suggests this strategy could be implemented in an agronomical manage for controlling the H. obscurus, the primary pest.
ARQUIVO SECRETO DO VATICANO Expansão portuguesa. Documentação Tomo I – COSTA OCIDENTAL DE ÁFRICA E ILHAS ATLÂNTICAS
Creators: name: Manuel, Clemente
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2013

description: Coordenação: José Eduardo Franco Editora: Esfera do Caos EditoresLisboa, 2011 – 2968 pp. (3 vols.)
description: Revista Lusófona de Ciência das Religiões, n. 16-17: Parte I: Para a História do Arquivo Secreto do Vaticano
SALT observations of southern post-novae
Creators: name: Tomov, T.
name: Swierczynski, E.
name: Mikolajewski, M.
name: Ilkiewicz, K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report on recent optical observations of the stellar and the nebular remnants of 22 southern post-novae. In this study, for each of our targets, we obtained and analysed long-slit spectra in the spectral range 3500-6600 A and in H$α$+NII narrow-band images. The changes in the emission lines' equivalent widths with the time since the outburst agree with earlier published results of other authors. We estimated an average value $α$=2.37 for the exponent of the power law fitted to the post-novae continua. Our observations clearly show the two-component structure of the V842 Cen expanding nebulae, owing to the different velocities of the ejected matter. We discovered an expanding shell around V382 Vel with an outer diameter of about 12 arcsec.
description: 24 pages, 19 figures, A&A accepted
In vitro antioxidant and anti-denaturation effects of Buglossoides purpurocaerulea (L.) I. M. Johnst. fruit extract
Creators: name: Marrelli, Mariangela
name: Amodeo, Valentina
name: Puntillo, Domenico
name: Statti, Giancarlo
name: Conforti, Filomena
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Fruits from Buglossoides purpurocaerulea (L.) I. M. Johnst. were extracted with methanol through maceration. The phytochemical composition of obtained raw extract was investigated with gas chromatography-mass spectrometry (GC-MS) and high-performance thin layer chromatography (HPTLC) analyses. The total phenolic and flavonoid contents were also quantified and in vitro antioxidant activity was assessed using the DPPH assay and the β-carotene bleaching test. In order to verify the anti-arthritic potential, the raw extract was evaluated for its anti-denaturation effect on heat-treated bovine serum albumin (BSA), chosen as a protein model. Linoleic and α-linolenic acids were the most abundant identified apolar constituents. HPTLC analyses allowed the identification of rosmarinic acid. The sample showed a concentration-dependent antioxidant activity and it was also proven to be effective in preventing the heat-induced denaturation of BSA, with an IC50 value equal to 15.7 ± 0.5 µg/mL.
JESUÍTAS E INQUISIÇÃO: CUMPLICIDADES E CONFRONTAÇÕES
Creators: name: Serrano, Juan Ignácio Pulido
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2013

description: José Eduardo Franco e Célia Cristina Tavares Editora: Editora da Universidade Estadual do Rio de Janeiro Rio de Janeiro, 2007 – 133 pp.
description: Revista Lusófona de Ciência das Religiões, n. 16-17: Parte I: Para a História do Arquivo Secreto do Vaticano
DESIRE6G Horizon Europe projekt bemutatása (A brief Introduction) - A 6G Architecture based on deeply programmable networks
Creators: name: Laki, Sandor
Publisher: name: Zenodo
Year: 2023

description: DESIRE6G Horizon Europe projekt bemutatása - A brief Introduction of the DESIRE6G Horizon Europe project

Plenary meeting of 5G Coalition (5G Koalíció plenáris meeting) in Budapest (June 22, 2023)

Organized by Neumann Technology Platform, a supporting institution of the Hungarian Ministry for National Economy, supports the development of Hungarian industrial strategy, and ensures the creation of the operating conditions for platforms and coalitions for the development of the ecosystem of certain priority technologies, with special regard to 5G, Artificial Intelligence, Blockchain, Drone, and Industry 4.0 technologies.
Epigenetic markers by DNA methylation in liquid biopsy for early detection of colorectal cancer: systematic review.
Creators: name: Mora Guerra, Jesús Alejandro
Publisher: name: Zenodo
Year: 2022

description: Background:
 Colorectal cancer (CRC), besides being one of the most common cancers, is one of the leading causes of cancer deaths worldwide. Studies reported discrepancies in clinical cases where the cancer was at the same stage, due to the molecular heterogeneity of tumors, so it is important to identify biomarkers that facilitate CRC prognosis [1].
 Epigenetic changes have gained great importance in recent decades due to their potential as biomarkers for the prognosis, diagnosis and treatment of various diseases, including cancer. One of the mechanisms that regulates epigenetic changes in the organism is DNA methylation, which adds chemical groups to the DNA strand affecting the expression of specific genes.
 In 2015, Wen-Han Li et al. demonstrated that SNCA and FNB1 genes show higher hypermethylation in CRC patients than in control samples. The combined sensitivity and specificity of at least one of these genes in fecal samples are 84.3% and 93.3, respectively [2]. Similarly in 2016, Wu D. et al. developed a simplified SEPT9 methylation assay which showed a decrease in sensitivity (76.6%) but showed an increase in specificity of (95.9%) [3].
 On the other hand, in 2018, Jensen S. Ø. et al. identified C9orf50, KCNQ5, and CLIP4 as markers able to discriminate plasma from CRC patients and healthy patients, and by using the combination of these genes, the tests showed an average sensitivity of 85% and specificity of 99% [4].
 In contrast, Han Y. D. et al. based their study on an individual gene, syndecan-2 gene (SDC2), as a biomarker using fecal samples for early cancer detection, which showed a sensitivity of 89.1% and specificity of 90.2% [5].
 Finally, in 2021, Overs A. et al. demonstrated that the NPY and WIF1 genes are found with increased hypermethylation in tumor tissue and, in a liquid biopsy, show a sensitivity of 95.5% and specificity of 100% [6].
 Based on the above, different genes have been identified that can be used for CRC detection, however, it has not yet been defined which of these have higher sensitivity and specificity values, therefore, it is important to conduct a study where these genes are evaluated and thus determine the one that has the optimal characteristics to be implemented as a clinical tool that will increase the rates of early detection of CRC and thus reduce the mortality rate.
Strong conciseness of coprime commutators in profinite groups
Creators: name: Heras, Iker de las
name: Pintonello, Matteo
name: Shumyatsky, Pavel
Publisher: name: arXiv
Year: 2023
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics

description: Let $G$ be a profinite group. The coprime commutators $γ_j^*$ and $δ_j^*$ are defined as follows. Every element of $G$ is both a $γ_1^*$-value and a $δ_0^*$-value. For $j\geq 2$, let $X$ be the set of all elements of $G$ that are powers of $γ_{j-1}^*$-values. An element $a$ is a $γ_j^*$-value if there exist $x\in X$ and $g\in G$ such that $a=[x,g]$ and $(|x|,|g|)=1$. For $j\geq 1$, let $Y$ be the set of all elements of $G$ that are powers of $δ_{j-1}^*$-values. The element $a$ is a $δ_j^*$-value if there exist $x,y\in Y$ such that $a=[x,y]$ and $(|x|,|y|)=1$. In this paper we establish the following results. A profinite group $G$ is finite-by-pronilpotent if and only if there is $k$ such that the set of $γ_k^*$-values in $G$ has cardinality less than $2^{\aleph_0}$. A profinite group $G$ is finite-by-(prosoluble of Fitting height at most $k$) if and only if there is $k$ such that the set of $δ_k^*$-values in $G$ has cardinality less than $2^{\aleph_0}$.
Tame systems of linear and semilinear mappings
Creators: name: Klimchuk, Tatiana
name: Kovalenko, Dmitry
name: Rybalkina, Tetiana
name: Sergeichuk, Vladimir V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 15A04, 15A21, 16G60

description: We study systems of linear and semilinear mappings considering them as representations of a directed graph $G$ with full and dashed arrows: a representation of $G$ is given by assigning to each vertex a complex vector space, to each full arrow a linear mapping, and to each dashed arrow a semilinear mapping of the corresponding vector spaces. We extend to such representations the classical theorems by Gabriel about quivers of finite type and by Nazarova, Donovan, and Freislich about quivers of tame types.
RELIGIOUS DIVERSITY IN ANCIENT ISRAEL AND JUDAH
Creators: name: Pinto, Porfírio
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2013

description: Francesca Stavrakopouloue John Barton (eds.) Editora: T&T ClarkNova Iorque, 2010 – 207 pp (+XVI) Disponibilidade em Portugal:Wook
description: Revista Lusófona de Ciência das Religiões, n. 16-17: Parte I: Para a História do Arquivo Secreto do Vaticano
Results from lattice simulations of N=4 supersymmetric Yang--Mills
Creators: name: Catterall, Simon
name: Giedt, Joel
name: Schaich, David
name: Damgaard, Poul H.
name: DeGrand, Thomas
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We report recent results and developments from our ongoing lattice studies of $\mathcal N = 4$ supersymmetric Yang--Mills theory. These include a proof that only a single fine-tuning needs to be performed, so long as the moduli space is not lifted by nonperturbative effects. We extend our investigations of supersymmetry restoration in the continuum limit by initiating Monte Carlo renormalization group studies. We present additional numerical evidence that the lattice theory does not suffer from a sign problem. Finally we study the static potential, which we find to be Coulombic at both weak and strong coupling. We compare the static potential Coulomb coefficients to perturbation theory, including initial results for N=3 colors in addition to N=2.
description: 19-page combined contribution to the proceedings of Lattice 2014, for talks by SC, JG & DS. v2: Eq. 6.3 corrected, reference added
DANÇA DOS DEMÓNIOS – Intolerância em Portugal
Creators: name: Ieri, Maurício
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2013

description: José Eduardo Francoe António Marujo(coords.) Editora: Círculo de Leitores Lisboa, 2009
description: Revista Lusófona de Ciência das Religiões, n. 16-17: Parte I: Para a História do Arquivo Secreto do Vaticano
Interpolation of inverse operators for preconditioning parameter-dependent equations
Creators: name: Zahm, Olivier
name: Nouy, Anthony
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: We propose a method for the construction of preconditioners of parameter-dependent matrices for the solution of large systems of parameter-dependent equations. The proposed method is an interpolation of the matrix inverse based on a projection of the identity matrix with respect to the Frobenius norm. Approximations of the Frobenius norm using random matrices are introduced in order to handle large matrices. The resulting statistical estimators of the Frobenius norm yield quasi-optimal projections that are controlled with high probability. Strategies for the adaptive selection of interpolation points are then proposed for different objectives in the context of projection-based model order reduction methods: the improvement of residual-based error estimators, the improvement of the projection on a given reduced approximation space, or the recycling of computations for sampling based model order reduction methods.
Additional file 1 of Physical activity and quality of life in children with idiopathic toe walking: a cross sectional study
Creators: name: Caserta, Antoni
name: Reedman, Sarah
name: Morgan, Prue
name: Williams, Cylie M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Supplementary data table 1. Frequency of types of the types and number of children participating in the CLASS categories of physical activity and screen time categories.
Optimal Hardy-Littlewood type inequalities for $m$-linear forms on $\ell_{p}$ spaces with $1\leq p\leq m$
Creators: name: Araujo, Gustavo
name: Pellegrino, Daniel
Publisher: name: arXiv
Year: 2015
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: The Hardy-Littlewood inequalities for $m$-linear forms on $\ell_{p}$ spaces are stated for $p>m$. In this paper, among other results, we investigate similar results for $1\leq p\leq m.$ Let $\mathbb{K}$ be $% \mathbb{R}$ or $\mathbb{C}$ and $m\geq 2$ be a positive integer. Our main results are the following sharp inequalities: (i) If $\left(r,p\right) \in \left(\lbrack 1,2]\times \lbrack 2,2m)\right) \cup \left(\lbrack 1,\infty)\times \lbrack 2m,\infty \right)) $, then there is a constant $D_{m,r,p}^{\mathbb{K}}>0$ (not depending on $% n $) such that \begin{equation*} \textstyle\left(\sum\limits_{j_{1},...,j_{m}=1}^{n}\left\vert T(e_{j_{1}},...,e_{j_{m}})\right\vert ^{r}\right) ^{\frac{1}{r}}\leq D_{m,r,p}^{\mathbb{K}}n^{\max \left\{ \frac{2mr+2mp-mpr-pr}{2pr},0\right\} }\left\Vert T\right\Vert \end{equation*} for all $m$--linear forms $T:\ell_{p}^{n}\times \cdots \times \ell_{p}^{n}\rightarrow \mathbb{K}$ and all positive integers $n$. (ii) If $\left(r,p\right) \in \lbrack 2,\infty)\times (m,2m]$, then \begin{equation*} \textstyle\left(\sum\limits_{j_{1},...,j_{m}=1}^{n}\left\vert T(e_{j_{1}},...,e_{j_{m}})\right\vert ^{r}\right) ^{\frac{1}{r}}\leq \left(\sqrt{2}\right) ^{m-1}n^{\max \left\{ \frac{p+mr-rp}{pr},0\right\} }\left\Vert T\right\Vert \end{equation*} for all $m$--linear forms $T:\ell_{p}^{n}\times \cdots \times \ell_{p}^{n}\rightarrow \mathbb{K}$ and all positive integers $n.$ Moreover the exponents $\max \{ (2mr+2mp-mpr-pr)/2pr,0 \} $ in (i) and $\max \{(p+mr-rp)/pr,0 \} $ in (ii) are optimal.
K-Step Block Implicit Adams Method for Approximate Solution of Initial Value Problems using Eulerian Polynomial
Creators: name: osilagun, Johnson
name: Olagbenro,, Rodiyat
name: Abduganiy, Ridwanulahi
name: Odekunle, Matthew
Publisher: name: figshare
Year: 2022
Subjects: subject: 10399 Numerical and Computational Mathematics not elsewhere classified
subject: FOS: Mathematics
subject: 10301 Numerical Analysis

description: Abstract This paper constructs and applied a class of k-step Block Implicit Adams Method (BIAM) for the integration of first order initial value problems in which the Eulerian polynomial is employed as the basis function .The BIAM for the initial value problems is constructed via multistep collocation techniques and applied in block structure as simultaneous numerical integration which makes it self-starting. An analysis of BIAM shows that the proposed method is zero stable, consistent, convergence and A-stable. Application of the BIAM on some standard ordinary differential problems revealed that BIAM is efficient and a good approximating scheme.
PADRE ANTÓNIO VIEIRA – Grandes Pensamentos
Creators: name: Nicolau, Laura
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2013

description: José Eduardo Franco (coord.) Editora: Gradiva Lisboa, 2008 – 194 pp.
description: Revista Lusófona de Ciência das Religiões, n. 16-17: Parte I: Para a História do Arquivo Secreto do Vaticano
Current status and new perspectives on cosmic ray deuterons
Creators: name: Gomez-Coral, Diego Mauricio
name: Gerrity, Cory
name: Munini, Riccardo
name: von Doetinchem, Philip
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Deuterons are the most abundant secondary cosmic ray species in the Galaxy, but their study has been severely limited due to experimental challenges. In an era with new experiments and high-precision measurements in cosmic rays, having a low-uncertainty deuteron flux in a wide energy range becomes possible. The deuteron-over-helium ratio ($d$/$^4$He) is important to understand the propagation of cosmic rays in the Galaxy and in the heliosphere, complementing observations with heavier nuclei like the boron-to-carbon ratio. In this work, the most up-to-date results of the deuteron flux and the $d$/$^4$He ratio at the top of the atmosphere have been obtained using {\tt GALPROP} and a 3D solar modulation model. It was found that the simulation describes the deuteron flux and $d$/$^4$He data below 1\,GeV/$n$ within the uncertainties of the model. However, the model underestimates the best-published measurements available at high energy. This discrepancy suggests different effective diffusions have to be considered between secondary light species like deuterons and heavier nuclei. Either this is a consequence of a break in the universality of propagation between light and heavier nuclei or a lack of precision measurements, it is something AMS-02 will help to resolve in the near future.
description: References added, some text changed or added results remain unchanged
A multisensory non-invasive system for laughter analysis
Creators: name: Cosentino, Sarah
name: Burger, Susanne
name: Martin, Lara
name: Metze, Florian
name: Kishi, Tatsuhiro
name: Hashimoto, Kenji
name: Sessa, Salvatore
name: Zecca, Massimiliano
name: Takanishi, Atsuo
Publisher: name: Figshare
Year: 2018
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: Laughter is an important non-verbal human social signal. Clarifying the mechanism of laughing would be useful in a variety of studies on health or sociology. In this paper we introduce a non-invasive multisensory system for real-time laughter detection and analysis. We focus only on the audio laughter recognition, present the preliminary results we obtained, and discuss the possible application of this system in the medical field
Analysis of Gender Normalization using MLP and VTLN Features
Creators: name: Schaaf, Thomas
name: Metze, Florian
Publisher: name: Figshare
Year: 2018
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: This paper analyzes the capability of multilayer perceptron frontends to perform speaker normalization. We find the context decision tree to be a very useful tool to assess the speaker normalization power of different frontends. We introduce a gender question into the training of the phonetic context decision tree. After the context clustering the gender specific models are counted. We compare this for the following frontends: (1) Bottle-Neck (BN) with and without vocal tract length normalization (VTLN), (2) standard MFCC, (3) stacking of multiple MFCC frames with linear discriminant analysis (LDA). We find the BN-frontend to be even more effective in reducing the number of gender questions than VTLN. From this we conclude that a Bottle-Neck frontend is more effective for gender normalization. Combining VTLN and BN-features reduces the number of gender specific models further.
Resveratrol plus low-dose hydroxyurea compared to high-dose hydroxyurea alone is more effective in γ-globin gene expression and ROS reduction in K562 cells
Creators: name: Alipour, Maedeh
name: Nasiri, Nahid
name: Kazemi, Fariba
name: Zare, Farahnaz
name: Sharifzadeh, Sedigheh
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Hydroxyurea (HU) is an anti-cancer drug that is used for the treatment of hemoglobinopathies as a γ-globin inducer. However, its dose-dependent effects have hampered its clinical reliability. Resveratrol (RSV) is an antioxidant and γ-globin inducer. The present study aimed to assess their combined effects on the γ-globin gene expression and reactive oxygen species (ROS) level of K562 cells. The results indicated that the γ-globin gene expression was approximately two folds higher in the group treated with RSV 50 µM + HU 25 µM in comparison to HU 100 μM alone (***p < 0.001). However, there was an inverse relationship between the expression of γ-globin gene and HU concentration in the combined groups. Furthermore, the combinations of RSV and HU significantly reduced ROS levels compared to single drugs. Overall, the combination of these compounds was an appropriate strategy for increasing γ-globin expression, reducing oxidant levels, and alleviating the adverse effects of HU.
title: Developing a charge plunger method for lifetime measurements in heavy elements
Creators: name: Heery, Jacob
Publisher: name: University of Liverpool Repository
Year: 2021

description: The use of the charge plunger method with a mass recoil separator provides a means of measuring the lifetime of low-lying states in exotic nuclei which de-excite via transitions with large internal conversion coefficients. These lifetime measurements provide tests for theoretical models predicting the structure of nuclei far from stability. The charge plunger method was used in an experiment at the University of Jyväskylä Accelerator Laboratory with the purpose of measuring the lifetime of excited states in ¹⁷⁸Pt which de-excite through γ-ray transitions and internal electron conversions. The DPUNS plunger device was connected to the in-flight mass separator MARA which separated ions by their charge state. Ionic charge-state distributions (CSD) were then observed at the focal plane of MARA. The JUROGAM 3 spectrometer surrounded DPUNS and was used to select ions in coincidence with γ-ray transitions in ¹⁷⁸Pt. Ionic charges were selected by MARA and measured at the focal plane in coincidence with the 4₁⁺→2₁⁺ 257 keV γ-ray transition detected using JUROGAM 3. The resulting CSD were analysed using the differential decay curve method (DDCM) framework to obtain a lifetime value of 430(20) ps for the 2₁⁺ state in ¹⁷⁸Pt. As an alternative analysis, ions were selected in coincidence with the ¹⁷⁸Pt alpha decay (Eₐ = 5.458(5) MeV) in the double-sided silicon strip detector (DSSSD) at the focal plane of MARA. Lifetime information was obtained by fitting a two-state Bateman equation to the decay curve with the lifetime of individual states defined by a single quadrupole moment. This yielded a lifetime value of 430(50) ps for the 2₁⁺ state, and 54(6) ps for the 4₁⁺ state. An analysis method based around the Bateman equation will become especially important when using the charge plunger method for the cases where utilising coincidences between prompt γ rays and recoils is not feasible.
COMMON CAUSES OF MEDICAL LITIGATION IN HEALTHCARE: INSIGHTS FROM ENUGU STATE UNIVERSITY TEACHING HOSPITAL, NIGERIA
Creators: name: Obi, Chinedu, P. E
Publisher: name: kEITH jOURNAL
Year: 2025
Subjects: Medical malpractice, medical errors, healthcare workforce, litigation, Nigeria

description: Medical malpractice is closely associated with medical errors, which refer to preventable adverse effects of care that deviate from established medical standards, often leading to patient harm. This study aimed to assess the most common causes of litigation among healthcare providers, specifically medical practitioners and nurses, at the Enugu State University Teaching Hospital (ESUTTH) in Enugu, South East Nigeria. A total of 300 healthcare workers, comprising 274 medical doctors and 26 nurses, participated in a cross-sectional survey conducted between February and June 2021. Participants' demographic information, including age, marital status, and years of practice, were collected, alongside their perspectives on the causes of medical malpractice litigation. Results indicated that 50% of participants attributed medical errors to the inexperience of healthcare providers, while 78% highlighted the reduced healthcare provider-to-patient ratio as a key contributor to medical errors. Additionally, 67% of respondents agreed that negligence by healthcare providers was a major cause of medical errors. The findings suggest that the most significant factor contributing to medical errors at ESUTTH is the inadequate healthcare provider-to-patient ratio, which increases workload, leading to fatigue and burnout among healthcare workers. The study underscores the importance of addressing this issue through improved workforce management, including government intervention and policies aimed at reducing the emigration of qualified healthcare professionals. A National Policy on Healthcare Workforce, if effectively implemented, may help mitigate the impact of medical errors and improve patient safety in Nigeria.
Automatically Assessing Personality from Speech
Creators: name: Polzehl, Tim
name: Moller, Sebastian
name: Metze, Florian
Publisher: name: Figshare
Year: 2018
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: In this paper, we present first results on applying a personality assessment paradigm to speech input, and comparing human and automatic performance on this task. We cue a professional speaker to produce speech using different personality profiles and encode the resulting vocal personality impressions in terms of the "Big Five" NEO-FFI personality traits. We then have human raters, who do not know the speaker, estimate the five factors. We analyze the recordings using signal-based acoustic and prosodic methods and observe high consistency between the acted personalities, the raters' assessments, and initial automatic classification results. This presents a first step towards being able to handle personality traits in speech, which we envision will be used in future voice-based communication between humans and machines.
Additional file 1 of Transforming L1000 profiles to RNA-seq-like profiles with deep learning
Creators: name: Jeon, Minji
name: Xie, Zhuorui
name: Evangelista, John E.
name: Wojciechowicz, Megan L.
name: Clarke, Daniel J. B.
name: Ma’ayan, Avi
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. The file contains Tables S1–S2 and Figures S1–S72.
New Views of Old Proteins: Clarifying the Enigmatic Proteome
Creators: name: Burnum-Johnson, Kristin E
name: Conrads, Thomas P
name: Drake, Richard R
name: Herr, Amy E
name: Iyengar, Ravi
name: Kelly, Ryan T
name: Lundberg, Emma
name: MacCoss, Michael J
name: Naba, Alexandra
name: Nolan, Garry P
name: Pevzner, Pavel A
name: Rodland, Karin D
name: Sechi, Salvatore
name: Slavov, Nikolai
name: Spraggins, Jeffrey M
name: Van Eyk, Jennifer E
name: Vidal, Marc
name: Vogel, Christine
name: Walt, David R
name: Kelleher, Neil L
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: All human diseases involve proteins, yet our current tools to characterize and quantify them are limited. To better elucidate proteins across space, time, and molecular composition, we provide a >10 years of projection for technologies to meet the challenges that protein biology presents. With a broad perspective, we discuss grand opportunities to transition the science of proteomics into a more propulsive enterprise. Extrapolating recent trends, we describe a next generation of approaches to define, quantify, and visualize the multiple dimensions of the proteome, thereby transforming our understanding and interactions with human disease in the coming decade.
title: Διερεύνηση της κατανομής Li, Ce, La στην ιπτάμενη τέφρα Αχλάδας, με μεθόδους εμπλουτισμού και εκλεκτικές εκχυλίσεις
Creators: name: Τσιλικα Μαρια
Publisher: name: Technical University of Crete
Year: 2023

description: Στο πλαίσιο της κυκλικής οικονομίας υπάρχει έντονο επιστημονικό ενδιαφέρον για τεχνολογίες που στοχεύουν στην ανάκτηση μετάλλων στρατηγικής σημασίας από απόβλητα και παραπροϊόντα. Προκειμένου να σχεδιαστούν αποτελεσματικές διεργασίες ανάκτησης, απαιτείται λεπτομερής και σε βάθος γνώση του τρόπου εμφάνισης των μετάλλων στα υλικά αυτά. Στην παρούσα διπλωματική εργασία διερευνάται η κατανομή και οι τρόποι εμφάνισης των μετάλλων στρατηγικής σημασίας στην ιπτάμενη τέφρα από την καύση λιγνίτη από την περιοχή Αχλάδα στη Φλώρινα. Τα μέταλλα που μελετήθηκαν είναι το La και το Ce ως αντιπροσωπευτικά των ελαφριών σπάνιων γαιών και το Li. Για τη μελέτη εφαρμόστηκαν μαγνητικός διαχωρισμός και εκλεκτικές εκχυλίσεις. Συγκεκριμένα πραγματοποιήθηκαν:
1.	Χαρακτηρισμός του δείγματος της ιπτάμενης τέφρας:
•	Ορυκτολογική ανάλυση περιθλασιμετρία ακτίνων Χ (XRD)
•	Χημική ανάλυση (κύρια στοιχεία) με φασματομετρία ακτίνων Χ φθορισμού (XRF)
•	Ποσοτικός προσδιορισμός της περιεκτικότητας σε Li, La και Ce με φασματομετρία μάζας με επαγωγικά συζευγμένο κλάσμα (ICP-MS)
2.	Μαγνητικός διαχωρισμός αρχικού δείγματος ιπτάμενης τέφρας
3.	Εκλεκτικές εκχυλίσεις με HCl και HF
Στα προϊόντα του μαγνητικού διαχωρισμού και στα υπολείμματα από τις εκλεκτικές εκχυλίσεις πραγματοποιήθηκε ορυκτολογική ανάλυση και ποσοτικός προσδιορισμός Li, La και Ce με τις τεχνικές που χρησιμοποιήθηκαν για τον χαρακτηρισμό του αρχικού δείγματος.
Η συγκέντρωση σε  Li, La και  Ce μετρήθηκε 251, 79 και 151 mg/kg αντίστοιχα. Τα μέταλλα που μελετήθηκαν εμφανίζονται εμπλουτισμένα στην ιπτάμενη τέφρα της Αχλάδας σε σχέση με το φλοιό της γης, και τις τέφρες  παγκοσμίως. Φαίνεται επίσης ότι είναι συνδεμένα με τα ανόργανα αργιλοπυριτικά συστατικά του λιγνίτη και τον μουλλίτη και το άμορφο υλικό της ιπτάμενης τέφρας. Τόσο τα αποτελέσματα του μαγνητικού διαχωρισμού όσο και αυτά των εκλεκτικών εκχυλίσεων ενισχύουν την υπόθεση ότι τα μέταλλα που μελετήθηκαν συνδέονται με το άμορφο υλικό της ιπτάμενης τέφρας.
Updating the phase diagram of the archetypal frustrated magnet Gd3Ga5O12
Creators: name: Deen, P. P.
name: Florea, O.
name: Lhotel, E.
name: Jacobsen, H.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The applied magnetic field and temperature phase diagram of the archetypal frustrated magnet, Gd3Ga5O12, has been reinvestigated using single crystal magnetometry and polarised neutron diffraction. The updated phase diagram is substantially more complicated than previously reported and can be understood in terms of competing interactions with loops of spins, trimers and decagons, in addition to competition and interplay between antiferromagnetic, incommensurate and ferromagnetic order. Several additional distinct phase boundaries are presented. The phase diagram centers around a multiphase convergence to a single point at 0.9 T and ~ 0.35 K, below which, in temperature, a very narrow magnetically disordered region exists. These data illustrate the richness and diversity that arises from frustrated exchange on the 3 dimensional hyperkagome lattice.
Additional file 1 of Beta amyloid deposition and cognitive decline in Parkinson’s disease: a study of the PPMI cohort
Creators: name: Mihaescu, Alexander S.
name: Valli, Mikaeel
name: Uribe, Carme
name: Diez-Cirarda, Maria
name: Masellis, Mario
name: Graff-Guerrero, Ariel
name: Strafella, Antonio P.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Statistics
subject: FOS: Mathematics
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Table S1. Genetic alleles with Parkinson disease-associated variants for GBA, SNCA and LRRK2 alleles that were excluded in the Parkinson’s disease sample; all included Parkinson’s disease patients did not have these pathogenic alleles.
Combining Slot-based Vector Space Model for Voice Book Search
Creators: name: Cheongjae  Lee
name: Lee, Tatsuya
name: Rudnicky, Alexander
Publisher: name: Figshare
Year: 2018
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: We describe a hybrid approach to vector space model that improves accuracy in voice search for books. We compare different vector space approaches and demonstrate that the hybrid search model using a weighted sub-space model smoothed with a general model and a back-off scheme provides the best search performance on natural queries obtained from the Web.
EM-based Phoneme Confusion Matrix Generation for Low-resource Spoken Term Detection
Creators: name: Xu, Di
name: Wang, Yun
name: Metze, Florian
Publisher: name: Figshare
Year: 2018
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: The idea of using a data-driven phoneme confusion matrix (PCM) to enhance speech recognition and retrieval performance is not new to the speech community. Although empirical results show various degrees of improvements brought by introducing a PCM, the underlying data-driven processes introduced in most papers are rather ad-hoc and lack rigorous statistical justifications. In this paper we will focus on the statistical aspects of PCM generation, propose and justify a novel expectation-maximization based algorithm for data-driven PCM generation. We will evaluate the performance of the generated PCMs under the context of low-resource spoken term detection, with primary focus on out-of-vocabulary keywords.
DICIONÁRIO HISTÓRICO DAS ORDENS E INSTITUIÇÕES AFINS EMPORTUGAL - sob direcção de José Eduardo Franco, José Augusto Mourão e Ana Cristina da Costa Gomes
Creators: name: Real, Miguel
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2013

description: Editora: Gradiva (ISBN 9789896163693)Lisboa, 2010 – 1020 pp.
description: Revista Lusófona de Ciência das Religiões, n. 16-17: Parte I: Para a História do Arquivo Secreto do Vaticano
Controlled transition to different proton acceleration regimes: near-critical density plasmas driven by circularly polarized few cycle pulse
Creators: name: Choudhary, Shivani
name: Mondal, Sudipta
name: Margarone, Daniele
name: Kahaly, Subhendu
Publisher: name: arXiv
Year: 2023
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Applied Physics (physics.app-ph)
subject: Computational Physics (physics.comp-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We investigate the different facets of ion acceleration by a relativistically intense circularly polarized laser pulse interacting with thin near-critical density plasma targets. Our simulations establish that plasma density gradient and laser frequency chirp can be controlled to switch the interaction from the transparent to the opaque regimes of operation. This enables one to choose between a Maxwellian like ion energy distribution with a cut-off energy, in the relativistically transparent regime, or a quasi-monoenergetic spectrum, in the opaque regime. We subsequently demonstrate that a double-layer multi-species target configuration, can be effectively utilized for optimal generation of quasi mono-energetic ion bunches of a desired species. We finally demonstrate, the feasibility of generating mono-energetic proton beams with energy peak at $\mathcal{E}\approx20\sim40$ MeV with a narrow energy spread of $Δ\mathcal{E}/\mathcal{E}\approx18-28.6\%$ confined within a divergence angle of $\sim 175$ millirad at a reasonable laser peak intensity of $I_{0}\simeq 5.4\times 10^{20}\, \mathrm{W/cm^2}$.
description: 22 pages, 9 figures and 1 table
A segunda união - desideratum pungente e visões problematizadas no seio da Igreja Católica romana
Creators: name: Oliveira, Rui A. Costa
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2013

description: Deixamos um alerta, a não nos acomodarmos ao muito que já foi dito e refletido (dentro e fora do magistério eclesial), porque sabemos que não é nem foi o suficiente e que há muitíssimo caminho a percorrer na busca de soluções libertadoras que contribuam para o alívio de todos os que– numa fase das suas vidas, ou por erradas opções ou por imaturidade nas escolhas –se encontram, hoje, perante a aviltante incapacidade de harmonizar o amor de Deus e do mais próximo, que lhes suscita o coração, com a fria letrada lei canónica que a Instituição eclesial lhes aponta.
description: Revista Lusófona de Ciência das Religiões, n. 16-17: Parte I: Para a História do Arquivo Secreto do Vaticano
Symmetric extendibility of quantum states
Creators: name: Nowakowski, Marcin L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Studies on symmetric extendibility of quantum states become especially important in a context of analysis of one-way quantum measures of entanglement, distilabillity and security of quantum protocols. In this paper we analyse composite systems containing a symmetric extendible part with a particular attention devoted to one-way security of such systems. Further, we introduce a new one-way monotone based on the best symmetric approximation of quantum state. We underpin those results with geometric observations on structures of multi-party settings which posses in sub-spaces substantial symmetric extendible components. Finally, we state a very important conjecture linking symmetric-extendibility with one-way distillability and security of all quantum states analyzing behavior of private key in neighborhood of symmetric extendible states.
description: Revised version with main changes in section II, 9 pages, 1 figure, RevTex
Fungal biotransformation of carvone and camphor by Aspergillus flavus and investigation of cytotoxic activities of naturally obtained essential oils
Creators: name: Gazioglu, Isil
name: Zengin, Ozge Sultan
name: Akyildiz, Aysenur Gunaydin
name: Kurt, Belma Zengin
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: In this study, the biotransformation of carvone and camphor by Aspergillus flavus and the products were investigated. The biotransformation reaction of carvone by A. flavus resulted in the production of neodihydrocarveol, dihydrocarvone, 2-cyclohexene-1-one,2-methyl-5-(1-methylethenyl), limonene-1,2-diol, trans-p-mentha-1(7),8-dien-2-ol, p-menth-8(10)-ene-2,9-diol, and the biotransformation reaction of camphor resulted in the production of 2 -campholenic acid, 2-cyclohexene-1-one,2-hydroxy-4,4,6,6-tetramethyl, α-campholene aldehyde. The naturally produced essential oils by biotransformation of carvone and camphor were observed to be cytotoxic to breast cancer cells while no significant inhibition was seen in the healthy cell line. Additionally, biotransformation products had the highest inhibition (74%) against aflatoxin B1. The bioactivities of biotransformation products are promising, and they can be further investigated for their therapeutic potential as active agents.
CE$ν$NS Experiment Proposal at CSNS
Creators: name: Su, Chenguang
name: Liu, Qian
name: Liang, Tianjiao
Publisher: name: arXiv
Year: 2023
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The detection and cross-section measurement of Coherent Elastic Neutrino-Nucleus Scattering (CEνNS) are vital for particle physics, astrophysics, and nuclear physics. Therefore, a new CEνNS detection experiment is proposed in China. Undoped CsI crystals, each coupled with two Photon Multiplier Tubes (PMTs), will be cooled down to 77K and placed at the China Spallation Neutron Source (CSNS) to detect the CEνNS signals produced by neutrinos from stopped pion decays happening within the Tungsten target of CSNS. Owing to the extremely high light yield of pure CsI at 77K, even though it only has a neutrino flux 60\% weaker than the COHERENT experiment, the detectable signal event rate is still expected to be 0.074/day/kg (0.053/day/kg for COHERENT). Low radioactivity materials and devices will be used to construct the detector, and strong shielding will be applied to reduce the radioactive and neutron background. Dual-PMT readout should be able to reject PMT-related background, such as Cherenkov light and PMT dark noise. With all the strategies mentioned above, we hope to reach a 5.1σ signal detection significance within six months of data taking with a 12kg CsI. This presentation will discuss the experiment's design, as well as the estimation of the signal, various kinds of background, and expected signal sensitivity.
Additional file 2 of Beta amyloid deposition and cognitive decline in Parkinson’s disease: a study of the PPMI cohort
Creators: name: Mihaescu, Alexander S.
name: Valli, Mikaeel
name: Uribe, Carme
name: Diez-Cirarda, Maria
name: Masellis, Mario
name: Graff-Guerrero, Ariel
name: Strafella, Antonio P.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Statistics
subject: FOS: Mathematics
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2. Additional results provided for the Durbin–Watson tests used in the linear regression model as well as the full linear regression equations for each year.
O pensamento proto-nacionalizante de FernandoOliveira eAntónioVieira fundamentos sacralizantes da ideografia da nação portuguesa
Creators: name: Franco, José Eduardo
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2013

description: «A escrita da história assume também uma dimensão profética e entra ao serviço da afirmação de uma consciência nacionalizante; e, através de uma hermenêutica inteligentemente orientada,os escritores/cartógrafos da nacionalidade formulam as suas críticas em relação ao presente e advertem os contemporâneos, em tom profético, em relação aos riscos do futuro. Mas esta nostalgia não se fecha em si própria. Transforma-se em instrumento de combate,de crítica, abrindo para o sentido da esperança no seu intento de desvelamento e antecipação teleológica.»
description: Revista Lusófona de Ciência das Religiões, n. 16-17: Parte I: Para a História do Arquivo Secreto do Vaticano