cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Using Utility to Provision Storage Systems (CMU-PDL-07-106)
Creators: name: Strunk, John D.
name: Thereska, Eno
name: Faloutsos, Christos
name: Ganger, Gregory R.
Publisher: name: Carnegie Mellon University
Year: 2007
Subjects: subject: 80499 Data Format not elsewhere classified
subject: FOS: Computer and information sciences

description: Provisioning a storage system requires balancing the costs of the solution with the benefits that the solution will provide. Previous provisioning approaches have started with a fixed set of requirements and the goal of automatically finding minimum cost solutions to meet them. Those approaches neglect the cost-benefit analysis of the purchasing decision. Purchasing a storage system involves an extensive set of trade-offs between metrics such as purchase cost, performance, reliability, availability, power, etc. Increases in one metric have consequences for others, and failing to account for these trade-offs can lead to a poor return on the storage investment. Using a collection of storage acquisition and provisioning scenarios, we show that utility functions enable this cost-benefit structure to be conveyed to an automated provisioning tool, enabling the tool to make appropriate trade-offs between different system metrics including performance, data protection, and purchase cost.
title: [Neue Nr. 5225] Geisa / Geologische Karte
title: Geologische Karte 1:25000
titleType: AlternativeTitle
title: [Sheet No 5225] ; Geisa ; geological map
Creators: name: Koenen, Adolf Von
Publisher: name: Armann & Pillmeier, Cassel
Year: 1886

description: Geologische Karte 1: 25 000 mit Erläuterungen. Digitalisat des FID GEO (Fachinformationsdienst Geowissenschaften der festen Erde), erstellt durch das GDZ (Göttinger Digitalisierungszentrum), Karte aus dem Bestand der SUB Göttingen. GeoTIFF erstellt durch FID GEO, SUB Göttingen.
description: map
description: DFG, SUB Göttingen
Using Utility Functions to Control a Distributed Storage System (CMU-PDL-08-102)
Creators: name: Strunk, John D.
Publisher: name: Carnegie Mellon University
Year: 2008
Subjects: subject: 80499 Data Format not elsewhere classified
subject: FOS: Computer and information sciences

description: Provisioning, and later optimizing, a storage system involves an extensive set of trade-offs between system metrics, including purchase cost, performance, reliability, availability, and power. Previous work has tried to simplify provisioning and tuning tasks by allowing a system administrator to specify goals for various storage metrics. While this helps by raising the level of specification from low-level mechanisms to high-level storage system metrics, it does not permit trade-offs between those metrics. This dissertation goes beyond goal-based requirements by allowing the system administrator to use a utility function to specify his objectives. Using utility, both the costs and benefits of configuration and tuning decisions can be examined within a single framework. This permits a provisioning system to make automated trade-offs across system metrics, such as performance, data protection and power consumption. It also allows an automated optimization system to properly balance the cost of data migration with its expected benefits. This work develops a prototype storage provisioning tool that uses an administrator-specified utility function to generate cost-effective storage configurations. The tool is then used to provide examples of how utility can be used to balance competing objectives (e.g., performance and data protection) and to provide guidance in the presence of external constraints. A framework for using utility to evaluate data migration is also developed. This framework balances data migration costs (decreases to current system metrics) against the potential benefits by discounting future expected utility. Experiments show that, by looking at utility over time, it is possible to choose the migration speed as well as weigh alternate optimization choices to provide the proper balance of current and future levels of service.
The Reidemeister graph is a complete knot invariant
Creators: name: Barbensi, Agnese
name: Celoria, Daniele
Publisher: name: arXiv
Year: 2018
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: We describe two locally finite graphs naturally associated to each knot type K, called Reidemeister graphs. We determine several local and global properties of these graphs and prove that in one case the graph-isomorphism type is a complete knot invariant up to mirroring. Lastly, we introduce another object, relating the Reidemeister and Gordian graphs, and determine some of its properties.
description: 49 pages, 51 figures. Comments are welcome!
The Effectiveness of Sitting Position During Second Stage of Labor among Primiparae on Maternal and Neonatal Outcomes
Creators: name: AL-Dahiri, Hind
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Nursing
subject: FOS: Health sciences
subject: Nursing Midwifery

description: Background: For many years, the most advantageous labor position has been questioned. Lithotomy position is the most common position used in tertiary settings; however, the recommended position recently is the sitting. Labor position in the second stage of labor affects the maternal and fetal outcomes. Therefore, current study aims to compare the effectiveness of lithotomy and setting positions during second stage of labor on maternal and fetal outcomes. A quasi-experimental design was used with purposeful sampling method. Sample size: 120 low risk primiparous divided equally in sitting and lithotomy positions. Setting: Labor and delivery unit at KAUH, Jeddah. Sampling: Data collected over six months from January to June during the year 2020. Tool: A structured questionnaire divided into 5 parts. Data analysis: Chi-square test used with Post-hoc Bonferroni test to examine the significant differences between the two groups by the SPSS version 24.0 software. Results: results show a significant positive effects of sitting position on episiotomy rate, shortening the second stage of labor, mode of delivery, newborn arterial cord PH, Apgar score at one and five minutes of life, newborn transfer to the intensive care unit, and maternal satisfaction at the p-value <0.05. Conclusion and Recommendation: The sitting position during the second stage of labor has positive effects compared to the lithotomy position during the second stage of labor on maternal and fetal outcome. Women should have the right to be educated about the benefits of the sitting position during second stage of labor.
Using Speculative Execution to Automatically Hide I/O Latency (CMU-CS-01-172)
Creators: name: Chang, Fay W.
Publisher: name: Carnegie Mellon University
Year: 2001
Subjects: subject: 80499 Data Format not elsewhere classified
subject: FOS: Computer and information sciences

description: The gap between processing speeds and disk access times is widening. This trend is causing applications that must fetch data from disk to spend an increasing proportion of their execution times stalled on disk I/O. I/O prefetching, a well-known technique for hiding disk latency, has the potential to alleviate this problem, particularly when the data that needs to be fetched is distributed across multiple disks. A major hurdle to benefiting from this technique in practice is the difficulty of generating accurate and timely prefetches. In this dissertation, I put forth a new approach to generating accurate and timely prefetches without programmer involvement. The key to the proposed approach is its unique method for predicting what data an executing process will access in the future. The approach involves adding an execution of each target process's code that exploits spare processing cycles. These added executions skip some operations, like accesses to uncached data, so that they can run ahead of their target normal executions. This permits differences between the data values used during the added speculative executions and their target normal executions. Despite any such differences, the approach predicts that the data accesses encountered during speculative executions will often be the same as the data accesses that will be encountered during their target normal executions such that, by initiating prefetching of that data, speculative executions could reduce the I/O stall time of their target normal executions. To investigate the viability of this approach, I developed and evaluated SpecHint, a design and implementation for applying the approach automatically. SpecHint is based on binary modification and requires no operating system support specific to this approach. I evaluated SpecHint using six benchmarks from the TIP benchmark suite. Experiments demonstrate that, with the file system striped across four disks, SpecHint reduces the elapsed times of five of the benchmarks (text search, scientific visualization, object linking, and two database queries) by 24% to 71%, with an average of 53%. Moreover, simulation experiments suggest that, on future systems, the benefit of SpecHint would not decrease, and may even increase for some applications.
Visible Effects of Invisible Hidden Valley Radiation
Creators: name: Carloni, Lisa
name: Sjostrand, Torbjorn
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Assuming there is a new gauge group in a Hidden Valley, and a new type of radiation, can we observe it through its effect on the kinematic distributions of recoiling visible particles? Specifically, what are the collider signatures of radiation in a hidden sector? We address these questions using a generic SU(N)-like Hidden Valley model that we implement in Pythia. We find that in both the e+e- and the LHC cases the kinematic distributions of the visible particles can be significantly affected by the valley radiation. Without a proper understanding of such effects, inferred masses of "communicators" and of invisible particles can be substantially off.
description: 31 pages, 28 figures removed figure titles,updated 2 references,corrected typos
Strichartz estimates and wave equation in a conic singular space
Creators: name: Zhang, Junyong
name: Zheng, Jiqiang
Publisher: name: arXiv
Year: 2018
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: Spectral Theory (math.SP)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 42B37, 35Q40, 47J35

description: Consider the metric cone $X=C(Y)=(0,\infty)_r\times Y$ with the metric $g=\mathrm{d}r^2+r^2h$ where the cross section $Y$ is a compact $(n-1)$-dimensional Riemannian manifold $(Y,h)$. Let $Δ_g$ be the Friedrich extension positive Laplacian on $X$ and let $Δ_h$ be the positive Laplacian on $Y$, and consider the operator $\LL_V=Δ_g+V_0 r^{-2}$ where $V_0\in\CC^\infty(Y)$ such that $Δ_h+V_0+(n-2)^2/4$ is a strictly positive operator on $L^2(Y)$. In this paper, we prove the global-in-time Strichartz estimates without loss for the wave equation associated with the operator $\LL_V$ which verifies\cite[Remark 2.4]{wang} Wang's conjecture for wave equation. The range of the admissible pair is sharp and is influenced by the smallest eigenvalue of $Δ_h+V_0+(n-2)^2/4$. To prove the result, we show a Sobolev inequality and a boundedness of a generalized Riesz transform in this setting. In addition, as an application, we study the well-posed theory and scattering theory for energy-critical wave equation with small data on this setting of dimension $n\geq3$.
description: Comments are welcome! To appear in Mathematische Annalen
Modeling of Anthranilhydrazide (HL1) Salicylhydrazone and Its Copper Complexes Cu(I) and Cu(II) as a Potential Antimicrobial and Antituberculosis Therapeutic Candidate
Creators: name: Utsu, Patrick M.
name: Gber, Terkumbur E.
name: Nwosa, Deborah O.
name: Nwagu, Adanna D.
name: Benjamin, Innocent
name: Ikot, Immaculata J.
name: Eno, Ededet A.
name: Offiong, Offiong E.
name: Adeyinka, Adedabo
name: Louis, Hitler
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Antimicrobial and antituberculosis activities of transition metal complex Cu(I) and Cu(II) from salicylhydrazone of anthranihydrazide (HL1) have been theoretically investigated using DFT methods at ωB97XD, PBEPBE, MPW1PW91, HSEH1PBE, CAM-B3LYP/6-311++G(d,p) level of theory. Owing to the fact that microbial and tuberculosis attacked still prevail despite studies reported in the literatures. This study utilized a higher theoretical model to unravel necessary information about the possible application of the HL1 and its complexes as a potential drug candidate. The results obtained reveal that the ligand (HL1) had the higher energy gap for the HES and MPW whereas, it Cu(II) complex had the least energy gap making it more reactive in the biological environment compared to its counterpart. The Natural Bond orbital (NBO) analysis reveals molecular interactions are of four kinds; LP→BD*, LP→LP*, LP*→BD*, BD*→BD*, and BD*→LP* where the higher perturbation energy was observed from BD*(C2-C3) → BD*(C4- 5) with the energy of 231.74 kcal/mol. The vibration analysis shows that the studied complexes have 32 atoms and 90 normal modes, with 20 symmetric, 7 asymmetric, 31 bending, and 32 ring torsional distribution. And their theoretical wavelength of absorption was observed to be in good agreement with experimental reported values. Cu(II) was observed with the highest dipole moment and first-order hyperpolarizability (βtotal) with corresponding values of 9.30D and 19.268 which shows its can be good for medicinal application. Molecular docking screening showed that the ligand and its complexes have better antimicrobial activities compared to antituberculosis.
title: OBSERVATIONS OF H2S TOWARD OMC-1
Creators: name: MINH, YC
name: ZIURYS, LM
name: Irvine, William M.
name: MCGONAGLE, D
Publisher: name: University of Massachusetts Amherst
Year: 1990
Subjects: subject: Astrophysics and Astronomy

description: The published version is located at http://adsabs.harvard.edu/full/1990ApJ...360..136M
description: Observations of the 1(10) - 1(01) transition of interstellar H2S and its isotopes toward OMC-1 are reported. The fractional abundance of H2S in the quiescent regions of OMC-1 seems difficult to explain by currently known ion-molecular reactions. The fractional abundance of H2S relative to H2 is enhanced by a factor of 1000 in the hot core and the plateau relative to the quiescent clouds. The (HDS)/(H2S) abundance ratio in the hot core is estimated at 0.02 or less.
Highly Accurate Analytic Presentation of Solution of the Schrödinger Equation
Creators: name: Liverts, E. Z.
name: Drukarev, E. G.
name: Krivec, R.
name: Mandelzweig, V. B.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: High-precision approximate analytic expressions for energies and wave functions are found for arbitrary physical potentials. The Schrödinger equation is cast into nonlinear Riccati equation, which is solved analytically in first iteration of the quasi-linearization method (QLM). The zeroth iteration is based on general features of the exact solution near the boundaries. The approach is illustrated on the Yukawa potential. The results enable accurate analytical estimates of effects of parameter variations on physical systems.
description: 2 pages, 1 figure, submission for the Proceedings of the International Conference on Hadron Physics, 30 Aug - 3 Sep 2007, Canakkale, Turkey
AGB subpopulations in the nearby globular cluster NGC 6397
Creators: name: MacLean, B. T.
name: Campbell, S. W.
name: De Silva, G. M.
name: Lattanzio, J.
name: DOrazi, V.
name: Cottrell, P. L.
name: Momany, Y.
name: Casagrande, L.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: It has been well established that Galactic Globular clusters (GCs) harbour more than one stellar population, distinguishable by the anti-correlations of light element abundances (C-N, Na-O, and Mg-Al). These studies have been extended recently to the asymptotic giant branch (AGB). Here we investigate the AGB of NGC 6397 for the first time. We have performed an abundance analysis of high-resolution spectra of 47 RGB and 8 AGB stars, deriving Fe, Na, O, Mg and Al abundances. We find that NGC 6397 shows no evidence of a deficit in Na-rich AGB stars, as reported for some other GCs - the subpopulation ratios of the AGB and RGB in NGC 6397 are identical, within uncertainties. This agrees with expectations from stellar theory. This GC acts as a control for our earlier work on the AGB of M 4 (with contrasting results), since the same tools and methods were used.
description: 10 pages, 7 figures, 8 tables (2 online-only). Accepted for publication in MNRAS
Using Context to Assist in Personal File Retrieval (CMU-CS-06-147)
Creators: name: Soules, Craig A.N.
Publisher: name: Carnegie Mellon University
Year: 2006
Subjects: subject: 80499 Data Format not elsewhere classified
subject: FOS: Computer and information sciences

description: Personal data is growing at ever increasing rates, fueled by a growing market for personal computing solutions and dramatic growth of available storage space on these platforms. Users, no longer limited in what they can store, are now faced with the problem of organizing their data such that they can find it again later. Unfortunately, as data sets grow the complexity of organizing these sets also grows. This problem has driven a sudden growth in search tools aimed at the personal computing space, designed to assist users in locating data within their disorganized file space. Despite the sudden growth in this area, local file search tools are often inaccurate. These inaccuracies have been a long-standing problem for file data, as evidenced by the downfall of attribute-based naming systems that often relied on content analysis to provide meaningful attributes to files for automated organization. While file search tools have lagged behind, search tools designed for the world wide web have found wide-spread acclaim. Interestingly, despite significant increases in non-textual data on the web (e.g., images, movies), web search tools continue to be effective. This is because the web contains key information that is currently unavailable within file systems: context. By capturing context information, e.g., the links describing how data on the web is inter-related, web search tools can significantly improve the quality of search over content analysis techniques alone. This work describes Connections, a context-enhanced search tool that utilizes temporal locality among file accesses to provide inter-file relationships to the local file system. Once identified, these inter-file relationships provide context information, similar to that available in the world wide web. Connections leverages this context to improve the quality of file search results. Specifically, user studies with Connections see improvements in both precision and recall (i.e., fewer false-positives and false-negatives) over content-only search, and a live deployment found that users experienced reduced search time with Connections when compared to content-only search.
Synthesis of Novel DPPH-Free Radical Scavenger Se-Containing Fused Chalcogenophenes: 2-Alkyl-7-Cyano-4-Imino-3-Phenyl-6-(pyrrolidin-1-yl)-3,4-Dihydroselenopheno[3,2-d]Pyrimidines
Creators: name: Farzamnezhad, Iman
name: Sheikhi-Mohammareh, Seddigheh
name: Beyzaei, Hamid
name: Yarmohammadi, Elahe
name: Shiri, Ali
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Mental Health

description: A straightforward and effective strategy for the synthesis of novel 7-cyano-4-imino-3-phenyl-6-(pyrrolidin-1-yl)-2-substituted-3,4-dihydroselenopheno[3,2-d]pyrimidines have been accomplished through a base-promoted cascade addition/cyclization sequence employing phenyl isothiocyanate followed by the S-alkylation of the obtained fused Se-containing heterocyclic framework with various alkyl halides. Free radical scavenging activity of the synthesized selenium-containing structures was studied against DPPH, as well. Antioxidant activities as IC50 values were ranged from 12.19 to 91.08 µM. Unfused 3-amino-2,4-dicyano-5-(pyrrolidin-1-yl)selenophene was much more powerful antioxidant agent than ascorbic acid. Moreover, the promising antioxidant potentials were observed with selenopheno[3,2-d]pyrimidines. Taking into account the best antioxidant activity of S-benzylated derivative amongst pyrimidine-fused heterocycles and significant relationship between antioxidant activity of compounds and many of their biological potencies, using benzyl halides bearing electron donating groups on phenyl ring can probably improve their antioxidant capacities to make them more effective anti-cancer, anti-diabetic, anti-inflammatory and anti-neurodegenerative agents.
The Luminosity Function of Lyman alpha Emitters at Redshift z=7.7
Creators: name: Tilvi, Vithal
name: Rhoads, James E.
name: Hibon, Pascale
name: Malhotra, Sangeeta
name: Wang, Junxian
name: Veilleux, Sylvain
name: Swaters, Rob
name: Probst, Ron
name: Krug, Hannah
name: Finkelstein, Steven L.
name: Dickinson, Mark
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Lyman alpha (Lya) emission lines should be attenuated in a neutral intergalactic medium (IGM). Therefore the visibility of Lya emitters at high redshifts can serve as a valuable probe of reionization at about the 50% level. We present an imaging search for z=7.7 Lya emitting galaxies using an ultra-narrowband filter (filter width= 9A) on the NEWFIRM imager at the Kitt Peak National Observatory. We found four candidate Lya emitters in a survey volume of 1.4 x 10^4 Mpc^3, with a line flux brighter than 6x10^-18 erg/cm^2/s (5 sigma in 2" aperture). We also performed a detailed Monte-Carlo simulation incorporating the instrumental effects to estimate the expected number of Lya emitters in our survey, and found that we should expect to detect one Lya emitter, assuming a non-evolving Lya luminosity function (LF) between z=6.5 and z=7.7. Even if one of the present candidates is spectroscopically confirmed as a z~8 Lya emitter, it would indicate that there is no significant evolution of the Lya LF from z=3.1 to z~8. While firm conclusions would need both spectroscopic confirmations and larger surveys to boost the number counts of galaxies, we successfully demonstrate the feasibility of sensitive near-infrared (1.06 um) narrow-band searches using custom filters designed to avoid the OH emission lines that make up most of the sky background.
description: Published in ApJ, 3 figures
Chemical and valence reconstruction at the surface of SmB6 revealed with resonant soft x-ray reflectometry
Creators: name: Zabolotnyy, V. B.
name: Fürsich, K.
name: Green, R. J.
name: Lutz, P.
name: Treiber, K.
name: Min, Chul-Hee
name: Dukhnenko, A. V.
name: Shitsevalova, N. Y.
name: Filipov, V. B.
name: Kang, B. Y.
name: Cho, B. K.
name: Sutarto, R.
name: He, Feizhou
name: Reinert, F.
name: Hinkov, D. S. Inosov V.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Samarium hexaboride (SmB$_6$), a Kondo insulator with mixed valence, has recently attracted much attention as a possible host for correlated topological surface states. Here, we use a combination of x-ray absorption and reflectometry techniques, backed up with a theoretical model for the resonant $M_{4,5}$ absorption edge of Sm and photoemission data, to establish laterally averaged chemical and valence depth profiles at the surface of SmB$_6$. We show that upon cleaving, the highly polar (001) surface of SmB$_6$ undergoes substantial chemical and valence reconstruction, resulting in boron termination and a Sm$^{3+}$ dominated sub-surface region. Whereas at room temperature, the reconstruction occurs on a time scale of less than two hours, it takes about 24 hours below 50 K. The boron termination is eventually established, irrespective of the initial termination. Our findings reconcile earlier depth resolved photoemission and scanning tunneling spectroscopy studies performed at different temperatures and are important for better control of polarity and, as a consequence, surface states in this system.
Lorentzian LQG vertex amplitude
Creators: name: Pereira, Roberto
Publisher: name: arXiv
Year: 2007
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We generalize a model recently proposed for Euclidean quantum gravity to the case of Lorentzian signature. The main features of the Euclidean model are preserved in the Lorentzian one. In particular, the boundary Hilbert space matches the one of SU(2) loop quantum gravity. As in the Euclidean case, the model can be obtained from the Lorentzian Barrett-Crane model from a flipping of the Poisson structure, or alternatively, by adding a topological term to the action and taking the small Barbero-Immirzi parameter limit.
description: 9 pages; typos corrected and footnote added
Sea Ice Targeted Geoengineering Can Delay Arctic Sea Ice Decline but not Global Warming
Creators: name: Zampieri, Lorenzo
name: Goessling, Helge F.
Publisher: name: FID GEO
Year: 2019

description: To counteract global warming, a geoengineering approach that aims at intervening in the Arctic ice-albedo feedback has been proposed. A large number of wind-driven pumps shall spread seawater on the surface in winter to enhance ice growth, allowing more ice to survive the summer melt. We test this idea with a coupled climate model by modifying the surface exchange processes such that the physical effect of the pumps is simulated. Based on experiments with RCP 8.5 scenario forcing, we find that it is possible to keep the late-summer sea ice cover at the current extent for the next ∼60 years. The increased ice extent is accompanied by significant Arctic late-summer cooling by ∼1.3 K on average north of the polar circle (2021–2060). However, this cooling is not conveyed to lower latitudes. Moreover, the Arctic experiences substantial winter warming in regions with active pumps. The global annual-mean near-surface air temperature is reduced by only 0.02 K (2021–2060). Our results cast doubt on the potential of sea ice targeted geoengineering to mitigate climate change.
Antioxidant and Anticholinesterase Potentials of Novel 4,6-Dimethoxyindole based Unsymmetrical Azines: Synthesis, Molecular Modeling, In Silico ADME Prediction and Biological Evaluations
Creators: name: Bingul, Murat
name: Ercan, Selami
name: Boga, Mehmet
name: Bingul, Alev Arslanturk
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified

description: Chemically and biologically important -C = N-N = C- diimine linkage was used to build unsymmetrical azine systems with indole heterocyclic backbone and substituted aromatic carbaldehydes. Ten novel compounds 7a-j were synthesized by the Schiff base reaction of 4,6-dimethoxyindole-7-hydrazone 5 and a range of substituted carbaldehydes 6a-j with high yields and purities. The biological study was directed to identify the antioxidant potentials due to the expected electronic delocalization capability of designated linkage which is important for possible hydrogen or electron donation. The three different assays, namely DPPH free radical scavenging, ABTS cationic radical decolarization and CUPRAC (cupric reducing antioxidant capacity) were employed to detect the antioxidant properties. The antioxidant potentials were found to be moderate for ABTS and CUPRAC assays and the compound 7j was the most potent candidate for all the antioxidant assays. More importantly, the anticholinesterase properties were investigated by acetylcholinesterase (ACh) and butyrylcholinesterase (BCh) enzyme inhibition assays. The molecular docking studies were also carried out to determine the possible poses of ligands 7a-j in binding sites of enzymes and ligand-residue interactions. The synthesized compounds were found to be more effective for the anticholinesterase activity with three promising candidates 7d, 7h and 7j in the case of BChE inhibitions. The compound 7h was determined as the best candidate with the comparable IC50 values for AChE and better inhibition potency for BChE with 7j. A range of hydrophobic and hydrophilic interactions were detected for the designated compound 7h and 7j through different amino acid residues and the computational results were found to be compatible with the biological counterparts.
Photocatalytic degradation and pollutant-oriented structure-activity analysis of carbamazepine, ibuprofen and acetaminophen over faceted TiO2
Creators: name: Szymon Dudziak
name: Agnieszka Fiszka Borzyszkowska
name: Anna Zielińska-Jurek
Publisher: name: Gdańsk University of Technology
Year: 2023
Subjects: subject: CORRELATION MODEL
subject: CRYSTAL FACETS
subject: PHARMACEUTICALS DEGRADATION

description: Photocatalytic degradation of carbamazepine, ibuprofen, acetaminophen and phenol was studied in the presence
of anatase photocatalyst, exposing three different crystal facets in the majority of {0 0 1}, {1 0 0} or {1 0 1}. It
was found that octahedral anatase particles exposing {1 0 1} facets allow to achieve the best degradation and
mineralization of all persistent organic pollutants. This confirms that the previous findings, showing high {1 0 1}
activity, are not limited to phenol and could be generalized for other water pollutants. Based on the obtained results,
a correlation model including exposed TiO2 crystal facet and chemical hardness of the pollutant was developed
to predict the degradation rate of pollutants with a possibly diverse electronic structure. The structureactivity
analyses, based on the reactivity predictors obtained from the DFT calculations for all tested compounds,
have shown that pollutants with higher chemical hardness react faster with the photocatalyst. Alternatively, a
similar effect was observed for the higher HOMO-LUMO energy gap of the compound. This relation indicates that
for compounds with a low energy position of LUMO orbital, e.g., carbamazepine, process efficiency is not strictly
dependent on the stability of h+ generated organic radical, which is often pointed out as an initial reactive form.
Based on these results, a correlation model was developed for the first time to quantitatively describe the effect of
the facet-pollutant interactions based on their independent electronic properties. Finally, this was followed by
the detailed degradation study of the pharmaceuticals mixture, showing the impact of the total concentration
and role of active species on the degradation efficiency over facet-engineered TiO2 photocatalysts.
User Level Implementation of Scalable Directories (GIGA+) (CMU-PDL-08-107)
Creators: name: Sanket  Hase
name: Jayaraman, Aditya
name: Perneti, Vinay K.
name: Sundararaman  Sridharan
name: Swapnil V. Patil
name: Polte, Milo
name: Gibson, Garth A.
Publisher: name: Carnegie Mellon University
Year: 2008
Subjects: subject: 80499 Data Format not elsewhere classified
subject: FOS: Computer and information sciences

description: High performance computing applications are becoming increasingly widespread in a large number of fields. However the performance of I/O sub-systems within such HPC computing environments has not kept pace with extreme processing and communication speeds of such computing clusters. The problem of high performance is tackled by system architects by employing a variety of storage technologies such as Parallel File Systems. While such solutions serve to significantly alleviate the problem of I/O performance scaling they still a lot of roam for improvement because they not endeavor to significanly scale the performance of meta-data operations. Such a situation can easily arise in database or telecommunication applications that create thousands of files per second in a single directory. When this happens, the consequent performance degradation effected by the slowdown of meta-data operations can severely slowdown the performance of the overall I/O system. GIGA+ affords a potential solution to this crucial issue of meta-data performance scaling in I/O sub-systems. GIGA+ is a scalable directory service that aims to scale and parallelize meta-data operations.
The Response in Air Quality to the Reduction of Chinese Economic Activities During the COVID-19 Outbreak
Creators: name: Shi, Xiaoqin
name: Brasseur, Guy P.
Publisher: name: FID GEO
Year: 2020

description: During the COVID-19 outbreak that took place in early 2020, the economic activities in China were drastically reduced and accompanied by a strong reduction in the emission of primary air pollutants. On the basis of measurements made at the monitoring stations operated by the China National Environmental Monitoring Center, we quantify the reduction in surface PM2.5, NO2, CO, and SO2 concentrations in northern China during the lockdown, which started on 23 January 2020. We find that, on the average, the levels of surface PM2.5 and NO2 have decreased by approximately 35% and 60%, respectively, between the period 1 and 22 January 2020 and the period 23 January and 29 February 2020. At the same time, the mean ozone concentration has increased by a factor 1.5–2. In urban area of Wuhan, where drastic measures were adopted to limit the spread of the coronavirus, similar changes in the concentrations of PM2.5, NO2, and ozone are found.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 1107
Creators: name: de la Côte d'Or, Archives départementales
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1107, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1107, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Enzymatic AND Logic Gates Operated Under Conditions Characteristic of Biomedical Applications
Creators: name: Melnikov, Dmitriy
name: Strack, Guinevere
name: Zhou, Jian
name: Windmiller, Joshua Ray
name: Halamek, Jan
name: Bocharova, Vera
name: Chuang, Min-Chieh
name: Santhosh, Padmanabhan
name: Privman, Vladimir
name: Wang, Joseph
name: Katz, Evgeny
Publisher: name: arXiv
Year: 2010
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: Molecular Networks (q-bio.MN)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Experimental and theoretical analyses of the lactate dehydrogenase and glutathione reductase based enzymatic AND logic gates in which the enzymes and their substrates serve as logic inputs are performed. These two systems are examples of the novel, previously unexplored, class of biochemical logic gates that illustrate potential biomedical applications of biochemical logic. They are characterized by input concentrations at logic 0 and 1 states corresponding to normal and abnormal physiological conditions. Our analysis shows that the logic gates under investigation have similar noise characteristics. Both significantly amplify random noise present in inputs, however we establish that for realistic widths of the input noise distributions, it is still possible to differentiate between the logic 0 and 1 states of the output. This indicates that reliable detection of abnormal biomedical conditions is indeed possible with such enzyme-logic systems.
description: PDF, 29 pages
Spatio-Temporal Variations, Fugacity Fractions and Air-Soil Exchanges of PCBs in Industrial, Urban and Semi-Rural Sites
Creators: name: Sanli, Gizem Eker
name: Erkul, Seyma Nur
name: Tasdemir, Yücel
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: This study investigated the spatiotemporal variations in the occurrence of polychlorinated biphenyl (PCB) congeners both in soil and ambient air. Soil and air samples were taken simultaneously for three seasons (spring, summer, and autumn) from industrial, urban, and semi-rural areas in Bursa, Turkey. Light and medium PCB homologous groups were dominant in all samples. Total PCB (∑25 PCBs) concentrations in the air were 0.12 ± 0.13, 0.06 ± 0.07, and 0.08 ± 0.11 ng/m3 and in soil were 4.01.±2.38, 5.44 ± 3.14, and 3.66 ± 1.56 ng/g DM for summer, spring, and winter, respectively. Moreover, the samples were taken from different sites to determine the spatial fluctuations. The average ∑25 PCBs in the air were 0.22 ± 0.06, 0.03 ± 0.01, and 0.03 ± 0.02 ng/m3 and in soil were 7.08 ± 1.84, 2.98 ± 0.52, and 3.06 ± 0.70 ng/g DM for industrial, urban and semi-rural sites, respectively. Maximum air and soil PCB concentrations were determined in the industrial region. The spatiotemporal changes in the fugacity fractions and net fluxes were also examined. The direction of the PCB movement was assessed and the results indicated that soil was a diffusive source for PCBs. The calculated fugacity fractions (ff) were above 0.7 while average flux values were calculated as 0.65 ± 0.33 ng/m2-d, 0.21 ± 0.19 ng/m2-d, and 0.26 ± 0.27 ng/m2-day for industrial, urban and semi-rural regions, respectively.
D2.2 Behavioral analysis and operational  best practice
Creators: name: McCauley, Darren
Publisher: name: Zenodo
Year: 2022
Subjects: Energy-efficient buildings
Carbon footprint
Sustainable development
Behavioral analysis
Facilities management

description: This is Deliverable D2.2 Behavioural analysis and operational best practice, reviewing and summarizing the academic literature investigating energy-related carbon footprint behaviours in buildings over the last five years. There were included both, statistical and descriptive observations of each living lab, first on the basis of building type and secondly on geographic location. This dataset, representing all recent research into building occupants’ behaviours with regard to carbon footprint, will be made available as an open-access database of research articles indexed for their most relevant content.
Ursa Minor: Versatile Cluster-based Storage (CMU-PDL-05-104)
Creators: name: Abd-El-Malek, Michael
name: Courtright, William V.
name: Cranor, Chuck
name: Ganger, Gregory R.
name: Hendricks, James
name: Klosterman, Andrew J.
name: Mesnier, Michael
name: Prasad, Manish
name: Salmon, Brandon
name: Sambasivan, Raja R.
name: Shafeeq  Sinnamohideen
name: Strunk, John D.
name: Thereska, Eno
name: Wachs, Matthew
name: Wylie, Jay J.
Publisher: name: Carnegie Mellon University
Year: 2005
Subjects: subject: 80499 Data Format not elsewhere classified
subject: FOS: Computer and information sciences

description: No single encoding scheme or fault model is optimal for all data. A versatile storage system allows them to be matched to access patterns, reliability requirements, and cost goals on a per-data item basis. Ursa Minor is a cluster-based storage system that allows data-specific selection of, and on-line changes to, encoding schemes and fault models. Thus, different data types can share a scalable storage infrastructure and still enjoy specialized choices, rather than suffering from “one size fits all.” Experiments with Ursa Minor show performance benefits of 2–3× when using specialized choices as opposed to a single, more general, configuration. Experiments also show that a single cluster supporting multiple workloads simultaneously is much more efficient when the choices are specialized for each distribution rather than forced to use a “one size fits all” configuration. When using the specialized distributions, aggregate cluster throughput nearly doubled.
Understanding Customer Dissatisfaction with Underutilized Distributed File Servers (CMU-CS-96-158)
Creators: name: Riedel, Erik
name: Gibson, Garth A.
Publisher: name: Carnegie Mellon University
Year: 1996
Subjects: subject: 80499 Data Format not elsewhere classified
subject: FOS: Computer and information sciences

description: An important trend in the design of storage subsystems is a move toward direct network attachment. Network-attached storage offers the opportunity to off-load distributed file system functionality from dedicated file server machines and execute many requests directly at the storage devices. For this strategy to lead to better performance as perceived by users, the response time of distributed operations must improve. In this paper, we analyze measurements of an Andrew File System (AFS) server that we recently upgraded in an effort to improve client performance in our laboratory. While the original server's overall utilization was only about 3%, we show how burst loads were sufficiently intense to lead to periods of poor response time significant enough to trigger customer dissatisfaction. In particular, we show how, after adjusting for network load and traffic to non-project servers, 50% of the variation in client response time was explained by variation in server CPU utilization. That is, clients saw long response times in large part because the server was often over-utilized when it was used at all. Using these measures, we see that off-loading file server work in a network-attached storage architecture has the potential to benefit user response time. Computational power in such a system scales directly with storage capacity, so the slowdown during burst periods should be reduced.
ALMA Twenty-six arcmin$^2$ Survey of GOODS-S at One-millimeter (ASAGAO): X-ray AGN Properties of Millimeter-Selected Galaxies
Creators: name: Ueda, Y.
name: Hatsukade, B.
name: Kohno, K.
name: Yamaguchi, Y.
name: Tamura, Y.
name: Umehata, H.
name: Akiyama, M.
name: Ao, Y.
name: Aretxaga, I.
name: Caputi, K.
name: Dunlop, J. S.
name: Espada, D.
name: Fujimoto, S.
name: Hayatsu, N. H.
name: Imanishi, M.
name: Inoue, A. K.
name: Ivison, R. J.
name: Kodama, T.
name: Lee, M. M.
name: Matsuoka, K.
name: Miyaji, T.
name: Morokuma-Matsui, K.
name: Nagao, T.
name: Nakanishi, K.
name: Nyland, K.
name: Ohta, K.
name: Ouchi, M.
name: Rujopakarn, W.
name: Saito, T.
name: Tadaki, K.
name: Tanaka, I.
name: Taniguchi, Y.
name: Wang, T.
name: Wang, W. -H.
name: Yoshimura, Y.
name: Yun, M. S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We investigate the X-ray active galactic nucleus (AGN) properties of millimeter galaxies in the Great Observatories Origins Deep Survey South (GOODS-S) field detected with the Atacama Large Millimeter/submillimeter Array (ALMA), by utilizing the Chandra 7-Ms data, the deepest X-ray survey to date. Our millimeter galaxy sample comes from the ASAGAO survey covering 26 arcmin$^2$ (12 sources at a 1.2-mm flux-density limit of $\approx$0.6 mJy), supplemented by the deeper but narrower 1.3-mm survey of a part of the ASAGAO field by Dunlop et al.\ (2017). Fourteen out of the total 25 millimeter galaxies have Chandra counterparts. The observed AGN fractions at $z=1.5-3$ is found to be 90$^{+8}_{-19}$\% and $57^{+23}_{-25}$\% for the ultra/luminous infrared galaxies with $\log L_{\rm IR}/L_{\odot} = 12-12.8$ and $\log L_{\rm IR}/L_{\odot} = 11.5-12$, respectively. The majority ($\sim$2/3) of the ALMA and/or Herschel detected X-ray AGNs at $z=1.5-3$ appear to be star-formation dominant populations, having $L_{\rm X}$/ $L_{\rm IR}$ ratios smaller than the "simultaneous evolution" value expected from the local black-hole mass to stellar mass ($M_{\rm BH}$-$M_*$) relation. On the basis of the $L_{\rm X}$ and stellar mass relation, we infer that a large fraction of star-forming galaxies at $z=1.5-3$ have black hole masses smaller than those expected from the local $M_{\rm BH}$-$M_*$ relation. This is opposite to previous reports on luminous AGN at same redshifts detected in wider and shallower surveys, which are subject to selection biases against lower luminosity AGN. Our results are consistent with an evolutionary scenario that star formation occurs first, and an AGN-dominant phase follows later, in objects finally evolving into galaxies with classical bulges.
description: 14 pages including 5 figures and 1 table, accepted for publication in ApJ
Non-equilibrium frequency-dependent noise through a quantum dot: A real time functional renormalization group approach
Creators: name: Moca, C. P.
name: Simon, P.
name: Chung, C. H.
name: Zarand, G.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We construct a real time current-conserving functional renormalization group (RG) scheme on the Keldysh contour to study frequency-dependent transport and noise through a quantum dot in the local moment regime. We find that the current vertex develops a non-trivial non-local structure in time, governed by a new set of RG equations. Solving these RG equations, we compute the complete frequency and temperature-dependence of the noise spectrum. For voltages large compared to the Kondo temperature, $eV \gg k_BT_K$, two sharp anti-resonances are found in the noise spectrum at frequencies $\hbar ω= \pm e V$, and correspondingly, two peaks in the ac conductance through the dot.
description: 4 pages, 4 figures
What spatial geometry does the (2+1)-dimensional QFT vacuum prefer?
Creators: name: Fischetti, Sebastian
name: Wallis, Lucas
name: Wiseman, Toby
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider relativistic (2+1)-QFTs on a product of time with a two-space and study the vacuum free energy as a functional of the temperature and spatial geometry. We focus on free scalar and Dirac fields on arbitrary perturbations of flat space, finding that the free energy difference from flat space is finite and always \textit{negative} to leading order in the perturbation. Thus free (2+1)-QFTs appear to always energetically favor a crumpled space on all scales; at zero temperature this is a purely quantum effect. Importantly, we show that this quantum effect is non-negligible for the relativistic Dirac degrees of freedom on monolayer graphene even at room temperature, so we argue that this vacuum energy effect should be included for a proper analysis of the equilibrium configuration of graphene or similar materials.
description: 5+2 pages; v2: addressed referee comments, fixed table 1