cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Philhedra KOKEN 1889
Creators: name: Mergl, Michal
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Brachiopoda
Craniata
Craniida
Craniidae
Philhedra

description: Genus Philhedra KOKEN, 1889
 Type species: Philhedra baltica KOKEN, 1889; Middle Ordovician, Estonia.
description: Published as part of Mergl, Michal, 2012, Lingulate And Craniate Brachiopods From The Top Of The Králův Dvůr Formation (Latest Katian) And Their Contribution To Palaeogeography, pp. 35-46 in Acta Musei Nationalis Pragae Series B 68 (1 - 2) on page 42, DOI: 10.5281/zenodo.13190994
U.S. Dairy Goat Operations
Creators: name: , Animal
name: , Animal
Publisher: name: Unknown
Year: 2012
Subjects: subject: Farm Management
subject: Livestock Production/Industries
subject: Marketing
subject: FOS: Economics and business

description: Excerpts from the report: Goat milk is used for human consumption and to feed goat kids and other livestock. For human consumption, goat milk is used primarily in cheese production and is also consumed as milk, cultured milk products, ice cream, and butter. In the United States, goat milk and other dairy goat products are valued by a growing number of connoisseur consumers. Because of its unique nutritional and biochemical properties, goat milk is also increasingly used by people with cow milk allergies and gastrointestinal disorders. While the demand for goat milk in the United States has not risen as fast as the demand for goat meat, there has been a steady expansion in goat milk production; the dairy goat inventory increased by 15 percent from 290,789 head in 2002 to 334,754 head in 2007. By January 1, 2011, the number of milk goats had increased to 360,000 head. The NAHMS Goat 2009 study was the first national study of the U.S. goat industry and was conducted in 21 of the Nation’s major goat-producing States. These States represented 75.5 percent of U.S. goat operations and 82.2 percent of U.S. goats. A stratified random sample of goat operations that kept at least one goat for meat, dairy, fiber, or other purposes was selected for the study.
description: Topics include milk production, feed and pasture management, milking procedures, milk quality, marketing, biosecurity and disease.
La Boucle du temps, de la racine de souche à l'arbre de Vie. (Part1)
Creators: name: Ouafae Lamraoui
Publisher: name: Zenodo
Year: 2024
Subjects: Physique
science
Théologie
Eschapsologie
Temps
Boucle du temps
Livre
Arbre de Vie

description: Une boucle temporelle est un objet physique théorique qui forme un anneau imaginaire fermé en deux positions opposées du temps reliées par le principe de causalité. Quoi qu’indémontrable, le phénomène est théoriquement rendu possible à travers l’espace-temps grâce à la physique classique. Les récits ésotériques du Livre décrivent subtilement le phénomène via la parabole de l’arbre de Vie qui illustre un temps généalogique horizontal établi d’un bout à l’autre de la Terre. La Transition ferme quant à elle l’allégorie de l’arbre par une boucle de causalité que met en mouvement la prophétie autoréalisatrice de la racine de souche. À partir du Point Ø, La période de transition est convertie en un système de coordonnées multidimensionnelles. Sur son plan de repère axial, les points de positions émanent de l’Arch qui est l’arc de voûte céleste située entre la Terre et les Cieux.
Supramolecular compounds of azo dyes derived from 1-phenylazo-2-naphthol and their nickel and copper complexes
Creators: name: Gilson Rodrigues Ferreira
name: Marcial, Bruna Luana
name: Garcia, Humberto Costa
name: Faulstich, Fabiano R.L.
name: Santos, Hélio F. Dos
name: Luiz Fernando C. De Oliveira
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: In this study, experimental techniques including Raman, infrared and X-ray crystal diffraction, as well as quantum chemistry calculations, are used to investigate two new azo dyes supramolecular complexes: 1-phenylazo-2-naphthol (Sudan I) with nickel(II) ion and 1-(2,4-xylylazo)-2-naphthol (Sudan II) with copper(II) ion. The crystallographic structures have been solved for bis-1-(pheny-l-azo)-2-naphtholatenickel(II) and bis-1-(2,4-xylylazo)-2-naphtholatecopper(II) complexes, revealing the presence of supramolecular interactions, such as the centroid–centroid π-stacking interactions and CH…π hydrogen interactions. These weak intermolecular interactions appear to play an important role on the crystal structure stability for both compounds. Density functional theory calculations at B3LYP/6-311++G(d,p) level were performed in order to help understanding such molecular interactions and to assign the vibrational spectra. The experimental and theoretical data have allowed the analysis of the packing forces, revealing charge accumulation at key molecular regions.
The Relationship Between Self-Esteem and Burnout Among College Students Amidst the Online Learning Modality
Creators: name: Gallardo, Pricious Nicole
name: Education, Psychology and
Publisher: name: figshare
Year: 2022
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology
subject: Developmental and Educational Psychology
subject: Education
subject: 160809 Sociology of Education
subject: FOS: Sociology

description: Self-esteem is a complex psychological structure whose changes are influenced by various factors. Thus, burnout is a stress- related disorder that arises when a person is subjected to prolonged stress without obtaining respite. Hence, these constructs affect the academic performance of the students. This study investigates the relationship between self-esteem and burnout among college students during the school year 2021-2022. Based on the statistical analysis, there is a significant relationship between self-esteem and burnout (r= .142).
Buckling-induced retraction of spherical shells: A study on the shape of aperture
Creators: name: Lin, Sen
name: Xie, Yi Min
name: Li, Qing
name: Huang, Xiaodong
name: Zhou, Shiwei
Publisher: name: Swinburne
Year: 2024

description: Buckling of soft matter is ubiquitous in nature and has attracted increasing interest recently. This paper studies the retractile behaviors of a spherical shell perforated by sophisticated apertures, attributed to the buckling-induced large deformation. The buckling patterns observed in experiments were reproduced in computational modeling by imposing velocity-controlled loads and eigenmode-affine geometric imperfection. It was found that the buckling behaviors were topologically sensitive with respect to the shape of dimple (aperture). The shell with rounded-square apertures had the maximal volume retraction ratio as well as the lowest energy consumption. An effective experimental procedure was established and the simulation results were validated in this study.
The targum (1919:Sept. 24)
Creators: name: No Name Supplied
Publisher: name: Targum Association
Year: 1919

description: Some University historians indicate that the Targum was first published as an annual in 1867, but of this we have no extant evidence. In January 1869, the Targum as we now know it, made its appearance as a monthly paper that concerned itself with student “literary contributions” and college news as well as serving as a vehicle for bringing news to alumni and the general public. The newspaper, which originally was for sale, varied in frequency over the years as did its title (The Targum, Rutgers Targum, Rutgers Daily Targum, and Daily Targum). The newspaper has continuously been published since 1869 with the exception of 19 months during the second world war, between February 1944 and October 1945. The Targum was published by the students of Rutgers College, and later Rutgers University—New Brunswick represented through the years as the Targum Association, Rutgers Targum Association, and Rutgers College Targum. As a student organization, the Targum operated under the oversight of the dean of students and student government but in October 1980, the Targum became an independent college paper.
MPEC 2024-K107 : 2010 FC81
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
A Kirigami Approach to Forming a Synthetic Buckliball
Creators: name: Lin, Sen
name: Xie, Yi Min
name: Li, Qing
name: Huang, Xiaodong
name: Zhou, Shiwei
Publisher: name: Swinburne
Year: 2024

description: The shape transformation of some biological systems inspires scientists to create sophisticated structures at the nano- and macro- scales. However, to be useful in engineering, the mechanics of governing such a spontaneous, parallel and large deformation must be well understood. In this study, a kirigami approach is used to fold a bilayer planar sheet featuring a specific pattern into a buckliball under a certain thermal stimulus. Importantly, this prescribed spherical object can retract into a much smaller sphere due to constructive buckling caused by radially inward displacement. By minimizing the potential strain energy, we obtain a critical temperature, below which the patterned sheet exhibits identical principal curvatures everywhere in the self-folding procedure and above which buckling occurs. The applicability of the theoretical analysis to the self-folding of sheets with a diversity of patterns is verified by the finite element method.
Health literacy strengths and challenges among residents of a resource-poor village in rural India: Epidemiological and cluster analyses
Creators: name: Passi, Reetu
name: Kaur, Manmeet
name: Lakshmi, P. V. M.
name: Cheng, Christina
name: Hawkins, Melanie
name: Osborne, Richard
Publisher: name: Swinburne
Year: 2024

description: No description available
title: Einmal Kanzler, immer Kanzler?: Warum eine Amtszeitbegrenzung für den Bundeskanzler nötig ist
Creators: name: Otto Lenz, Carl
Publisher: name: Fachinformationsdienst für internationale und interdisziplinäre Rechtsforschung
Year: 2018
Subjects: subject: 342

description: Verfassungsblog: On Matters Constitutional
A finite-element approach to evaluating the size effects of complex nanostructures
Creators: name: Lu, Dingjie
name: Xie, Yi Min
name: Li, Qing
name: Huang, Xiaodong
name: Li, Yang Fan
name: Zhou, Shiwei
Publisher: name: Swinburne
Year: 2024

description: The size effects that reveal the dramatic changes of mechanical behaviour at nanoscales have traditionally been analysed for regular beam systems. Here, the method of using finite-element analysis is explored with the intention of evaluating the size effects for complex nanostructures. The surface elasticity theory and generalized Young–Laplace equation are integrated into a beam element to account for the size effects in classical Euler–Bernoulli and Timoshenko beam theories. Computational results match well with the theoretical predictions on the size effect for a cantilever beam and a cubic unit cell containing 24 horizontal/vertical ligaments. For a simply supported nanowire, it is found that the results are very close to the experimental data. With the assumption that nanoporous gold is composed of many randomly connected beams, for the first time, the size effect of such a complex structure is numerically determined.
Supplementary material for "SHBG gene polymorphisms and their influence on serum SHBG, total and free testosterone concentrations in men".
Creators: name: Walravens, Joeri
name: Sleumer, Bas
name: J. Vos, Michel
name: Snaterse, Gido
name: Narinx, Nick
name: Antonio, Leen
name: Reyns, Tim
name: Fiers, Tom
name: Kema, Ido P.
name: Kaufman, Jean-Marc
name: C. van de Merbel, Nico
name: Lapauw, Bruno
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 320208
subject: Endocrinology

description: Supplementary material for JCEM submission titled "SHBG gene polymorphisms and their influence on serum SHBG, total and free testosterone concentrations in men".
The Relationship Between Self-Concept and Anxiety Among College Students During the Online Learning Modality
Creators: name: Baylon, Lovely
name: Education, Psychology and
Publisher: name: figshare
Year: 2022
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology
subject: Developmental and Educational Psychology
subject: Education
subject: 160809 Sociology of Education
subject: FOS: Sociology

description: Due to the overall high number of COVID-19 cases in the Philippines, students are restricted from studying in their homes. Hence, online learning developed consequences that influenced their self-concept and anxiety. The sudden and unexpected adjustment from face-to-face classes to online learning had significant effects on students' self-concept and educational achievement. Even though many students have received awards for their determination and hard work, their psychological health and self-concept remain their main priorities during the current pandemic. Anxiety is something that students face from time to time, as being lonely can impact their confidence. Moreover, this study investigates the relationship between self- concept and anxiety among college students. The statistical findings revealed a significant relationship between self-concept and anxiety (r =.148).
Fishnet metamaterial with double negative refractive index in blue region of visible spectrum
Creators: name: Zhou, Shiwei
name: Xie, Yi Min
name: Li, Qing
name: Huang, Xiaodong
Publisher: name: Swinburne
Year: 2024

description: By optimizing the shape and scale of perforations as well as the depth of different layers, we obtained a metal- dielectric-metal double fishnet metamaterial with an unbroken 38-nm bandwidth of negative refractive index in visible spectrum, spaning from 459 to 497 nm. Moreover, the real parts of permittivity and permeability of this metamaterial are simultaneously negative from 460 to 478 nm in wavelength, reaching a frequency band as high as to the blue region - a territory that has never been explored before in visible spectrum.
Cucurbit[6]uril dimer induces supramolecular polymerisation of a cationic polyethylene glycol derivative
Creators: name: Wittenberg, James B.
name: Isaacs, Lyle
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: Recently, we reported the synthesis of two new dimeric cucurbit[6]uril compounds (1 and 2). Herein, we describe the ability of compound 1 to undergo supramolecular polymerisation when combined with polyethylene glycol (PEG) derived divalent guests 3MW (MW = 300, 1000, 3350, 10,000). Interestingly, we find that the shorter PEG-derived guests 3300, 31000 and 33350 lead to low degrees of oligomerisation based on the diffusion coefficients obtained by diffusion-ordered spectroscopy measurements. In contrast, when 1 was combined with the longest PEG-derived guest 310,000, we observed the formation of a supramolecular polymer with a degree of oligomerisation of at least 36. We observe that the supramolecular polymer 1n·(310,000)n undergoes a slow decrease in its degree of oligomerisation to 22 over the course of 14 days controlled by the slow dissociation rate constant of the hexanediammonium unit of 310,000 from the CB[6]-sized cavity of 1.
Dynamic setting, verification and adjustment of upper bound constraints in grid workflow systems
Creators: name: Chen, Jinjun
name: Yang, Yun
Publisher: name: Swinburne
Year: 2024

description: Upper bound constraints are often set when complex scientific or business processes are modelled as grid workflow specifications. However, many existing processes such as climate modelling or international stock market analysis often have only one end-to-end upper bound constraint. This is not sufficient to control overall temporal correctness as we may not find temporal violations until the last activity. Then, it is too late to take any handling actions. Consequently, the execution results may not be useful and overall cost-effectiveness would be impacted. Therefore, in this paper, we systematically investigate how to set, verify and adjust sub-upper bound constraints within the timeframe of one end-to-end upper bound constraint so that we can control grid workflow execution locally. We develop corresponding setting, verification and adjustment methods and algorithms. The quantitative evaluation demonstrates that with sub-upper bound constraints, we can achieve better cost-effectiveness than only based on one end-to-end upper bound constraint.
Synthesis, characterization, equilibrium studies, and biological activity of complexes involving copper(II), 2-aminomethylthiophenyl-4-bromosalicylaldehyde Schiff base, and selected amino acids
Creators: name: Mutlaq S. Aljahdali
name: Abedelkarim, Abeer T.
name: El-Sherif, Ahmed A.
name: Ahmed, Mahmoud M.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: Ternary complexes of copper(II) with 2-aminomethylthiophenyl-4-bromosalicylaldehyde (ATS) and some amino acids have been isolated and characterized by elemental analyses, IR, magnetic moment, molar conductance, UV–vis, mass spectra, and ESR. The proposed general formulas of the prepared complexes are [Cu(ATS)(AA)]·nH2O (where AA = glycine, alanine, and valine). The low molar conductance values suggest the non-electrolytic nature of the complexes. IR spectra show that ATS is coordinated to copper in a bidentate manner through azomethine-N and phenolic-OH. The amino acids also are monobasic bidentate ligands via amino and ionized carboxylate groups. The magnetic and spectral data indicate the square-planar geometry of Cu(II) complexes. The geometry of the Cu(II) complexes has been fully optimized using parameterized PM3 semiempirical method. The Cu–N bond length is longer than that of Cu–O in the isolated complexes. Also, information is obtained from calculations of molecular parameters for all complexes including net dipole moment of the metal complexes, values of binding energy, and lipophilicity value (log P). The antimicrobial activity studies indicate significant inhibitory activity of complex 3 against the selected types of bacteria. The mixed ligand complexes have also been studied in solution state. Protonation constants of ATS and amino acids were determined by potentiometric titration in 50% (v/v) DMSO–water solution at ionic strength of 0.1 M NaCl. ATS has two protonation constants. The binary and ternary complexes of copper(II) involving ATS and some selected amino acids (glycine, alanine, and valine) were examined. Copper(II) forms [Cu(ATS)], [Cu(ATS)2], [Cu(AA)], [Cu(AA)2], and [Cu(ATS)(AA)] complexes. The ternary complexes are formed in a simultaneous mechanism.
Amélioration de la gestion de la chaîne logistique par l'étude de l'amplification de la variance
Creators: name: Reda Saib
name: My Abdelouhab Salahddine
Publisher: name: Zenodo
Year: 2024

description: Dans une ère de changements incessants et de demandes croissantes, les entreprises prennent de plus en plus conscience de l'ampleur des nouveaux défis auxquels elles sont confrontées. L'un de ces défis est l'amplification de la variance, où la variabilité des commandes dans la chaîne logistique augmente à mesure qu'elle s’éloigne de la demande des consommateurs. Les recherches révèlent qu’une simple hausse de 10 % de la demande au niveau de la vente au détail entraîne une augmentation considérable de 40 % au niveau de la fabrication. Cette amplification est due à une interaction complexe de dynamiques opérationnelles et comportementales. Pour contrer ce phénomène, des analyses des causes sous-jacentes sont menées par différents chercheurs dans ce domaine. Dans cette optique, l'objectif de cet article est, d'une part, de présenter les principales recherches sur les facteurs susceptibles d'amplifier significativement les oscillations des commandes et, d'autre part, d’exposer les études expérimentales menées sur l’amplification de la demande dans le cadre d'une chaîne d'approvisionnement décentralisée, à révision périodique et à échelons multiples.
Development Of A Robust Solid-State Reference Electrode
Creators: name: Egan, Sasha
Publisher: name: Zenodo
Year: 2020
Subjects: Reference
Electrode
Solid-State
Graphene
Nernstian
Reversible
Sensors
High-Temperature
Rugged

description: The classic liquid filled reference electrode is unreliable while operating within
 harsh environments where high temperatures and pressures are commonly encountered.
 A rugged, reliable, solid-state reference electrode which is not dependent upon a liquid
 element could prove to be a beneficial technological advance. This thesis presents the
 method of construction and test results of an experimental solid-state reference electrode
 built upon a graphene/graphite substrate which was evaluated using four different analytical
 methods-Cyclic Voltammetry (CV), Electrochemical Impedance Spectroscopy (EIS),
 Chronopotentiometry (Galvanostatic), and Potentiometry. The potentiometric, impedance,
 and galvanostatic studies examined the response of the experimental electrode at temperatures
 ranging from 293K-473K (20°C-200°C) and pressures exceeding 55 bar. The
 electrode response was tested in aqueous solutions of potassium iodide and potassium
 chloride with concentrations ranging from 1 to 1x10-5 mol L-1. The reference cell was
 evaluated against eight criteria points which a reliable, thermodynamically reversible, reference
 electrode is required to meet or exceed. These experimental electrodes provisionally
 passed seven of the eight criteria points and are constructed of materials which are
 both physically and chemically resilient. The observed potential remained stable during
 the initial long term observational study which exceeded 2500 consecutive operational
 hours. These electrodes have been shown to be thermodynamically complementary, reversible,
 and Nernstian.
description: Published by ProQuest LLC. (2020) Proquest Number: 28157416 Copyright of the Dissertation is held by the Author.
Synthesis, characterization, equilibrium studies, and biological activity of complexes involving copper(II), 2-aminomethylthiophenyl-4-bromosalicylaldehyde Schiff base, and selected amino acids
Creators: name: Mutlaq S. Aljahdali
name: Abedelkarim, Abeer T.
name: El-Sherif, Ahmed A.
name: Ahmed, Mahmoud M.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: Ternary complexes of copper(II) with 2-aminomethylthiophenyl-4-bromosalicylaldehyde (ATS) and some amino acids have been isolated and characterized by elemental analyses, IR, magnetic moment, molar conductance, UV–vis, mass spectra, and ESR. The proposed general formulas of the prepared complexes are [Cu(ATS)(AA)]·nH2O (where AA = glycine, alanine, and valine). The low molar conductance values suggest the non-electrolytic nature of the complexes. IR spectra show that ATS is coordinated to copper in a bidentate manner through azomethine-N and phenolic-OH. The amino acids also are monobasic bidentate ligands via amino and ionized carboxylate groups. The magnetic and spectral data indicate the square-planar geometry of Cu(II) complexes. The geometry of the Cu(II) complexes has been fully optimized using parameterized PM3 semiempirical method. The Cu–N bond length is longer than that of Cu–O in the isolated complexes. Also, information is obtained from calculations of molecular parameters for all complexes including net dipole moment of the metal complexes, values of binding energy, and lipophilicity value (log P). The antimicrobial activity studies indicate significant inhibitory activity of complex 3 against the selected types of bacteria. The mixed ligand complexes have also been studied in solution state. Protonation constants of ATS and amino acids were determined by potentiometric titration in 50% (v/v) DMSO–water solution at ionic strength of 0.1 M NaCl. ATS has two protonation constants. The binary and ternary complexes of copper(II) involving ATS and some selected amino acids (glycine, alanine, and valine) were examined. Copper(II) forms [Cu(ATS)], [Cu(ATS)2], [Cu(AA)], [Cu(AA)2], and [Cu(ATS)(AA)] complexes. The ternary complexes are formed in a simultaneous mechanism.
Assigning local fixed-time constraints in grid workflow systems
Creators: name: Chen, Jinjun
name: Yang, Yun
Publisher: name: Swinburne
Year: 2024

description: Many complex grid workflow processes often have only one global fixed-time constraint at the last activity. Since grid workflow execution normally lasts a long time, local control is very important to ensure the overall temporal correctness. With only one global fixed-time constraint, we cannot control grid workflow execution locally in terms of time. As a result, for any temporal violations, we must handle them globally with the consideration of all activities. This would impact the overall cost-effectiveness of grid workflow execution. Therefore, in this paper, we investigate how to assign local fixed-time constraints within the global one so that we can control grid workflow execution locally. Corresponding assigning and verification methods are developed. With local fixed-time constraints, we can achieve better cost-effectiveness.
Mental models of audit and feedback in primary care settings
Creators: name: Hysong, Sylvia J
name: Smitham, Kristen
name: SoRelle, Richard
name: Amspoker, Amber
name: Hughes, Ashley
name: Haidet, Paul
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: BACKGROUND: Audit and feedback has been shown to be instrumental in improving quality of care, particularly in outpatient settings. The mental model individuals and organizations hold regarding audit and feedback can moderate its effectiveness, yet this has received limited study in the quality improvement literature. In this study we sought to uncover patterns in mental models of current feedback practices within high- and low-performing healthcare facilities. METHODS: We purposively sampled 16 geographically dispersed VA hospitals based on high and low performance on a set of chronic and preventive care measures. We interviewed up to 4 personnel from each location (n = 48) to determine the facility's receptivity to audit and feedback practices. Interview transcripts were analyzed via content and framework analysis to identify emergent themes. RESULTS: We found high variability in the mental models of audit and feedback, which we organized into positive and negative themes. We were unable to associate mental models of audit and feedback with clinical performance due to high variance in facility performance over time. Positive mental models exhibit perceived utility of audit and feedback practices in improving performance; whereas, negative mental models did not. CONCLUSIONS: Results speak to the variability of mental models of feedback, highlighting how facilities perceive current audit and feedback practices. Findings are consistent with prior research in that variability in feedback mental models is associated with lower performance.; Future research should seek to empirically link mental models revealed in this paper to high and low levels of clinical performance.
Selecting necessary and sufficient checkpoints for dynamic verification of fixed-time constraints in grid workflow systems
Creators: name: Chen, Jinjun
name: Yang, Yun
Publisher: name: Swinburne
Year: 2024

description: In grid workflow systems, existing representative checkpoint selection strategies, which are used to select checkpoints for verifying fixed-time constraints at run-time execution stage, often select some unnecessary checkpoints and ignore some necessary ones. Consequently, overall temporal verification efficiency and effectiveness can be severely impacted. In this paper, we propose a new strategy that selects only necessary and sufficient checkpoints dynamically along grid workflow execution. Specifically, we introduce a new concept of minimum time redundancy as a key reference value for checkpoint selection. We also investigate its relationships with fixed-time constraint consistency. Based on these relationships, we present our strategy which can improve overall temporal verification efficiency and effectiveness significantly.
Chance in Evolutionary Theory: Fitness, Selection, and Genetic Drift in Philosophical and Historical Perspective
Creators: name: Pence, Charles
Publisher: name: figshare
Year: 2014
Subjects: subject: History
subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Evolutionary Biology
subject: FOS: Biological sciences

description: Discussions of the foundations of evolutionary theory -- especially natural selection, fitness, and genetic drift -- are saturated with terms referring to various kinds of chance, stochasticity, randomness, unpredictability, and so forth. This dissertation examines these uses of chance in philosophical and historical perspective.
BigBrain 3D atlas of cortical layers: Cortical and laminar thickness gradients diverge in sensory and motor cortices.
Creators: name: Wagstyl, Konrad
name: Larocque, Stéphanie
name: Cucurull, Guillem
name: Lepage, Claude
name: Cohen, Joseph Paul
name: Bludau, Sebastian
name: Palomero-Gallagher, Nicola
name: Lewis, Lindsay B
name: Funck, Thomas
name: Spitzer, Hannah
name: Dickscheid, Timo
name: Fletcher, Paul C
name: Romero, Adriana
name: Zilles, Karl
name: Amunts, Katrin
name: Bengio, Yoshua
name: Evans, Alan C
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Histological atlases of the cerebral cortex, such as those made famous by Brodmann and von Economo, are invaluable for understanding human brain microstructure and its relationship with functional organization in the brain. However, these existing atlases are limited to small numbers of manually annotated samples from a single cerebral hemisphere, measured from 2D histological sections. We present the first whole-brain quantitative 3D laminar atlas of the human cerebral cortex. It was derived from a 3D histological atlas of the human brain at 20-micrometer isotropic resolution (BigBrain), using a convolutional neural network to segment, automatically, the cortical layers in both hemispheres. Our approach overcomes many of the historical challenges with measurement of histological thickness in 2D, and the resultant laminar atlas provides an unprecedented level of precision and detail. We utilized this BigBrain cortical atlas to test whether previously reported thickness gradients, as measured by MRI in sensory and motor processing cortices, were present in a histological atlas of cortical thickness and which cortical layers were contributing to these gradients. Cortical thickness increased across sensory processing hierarchies, primarily driven by layers III, V, and VI. In contrast, motor-frontal cortices showed the opposite pattern, with decreases in total and pyramidal layer thickness from motor to frontal association cortices. These findings illustrate how this laminar atlas will provide a link between single-neuron morphology, mesoscale cortical layering, macroscopic cortical thickness, and, ultimately, functional neuroanatomy.
Dissecting the syndrome of schizophrenia: Progress toward clinically useful biomarkers
Creators: name: Dean, Brian
Publisher: name: Swinburne
Year: 2024

description: The search for clinically useful biomarkers has been one of the holy grails of schizophrenia research. This paper will outline the evolving notion of biomarkers and then outline outcomes from a variety of biomarkers discovery strategies. In particular, the impact of high-throughput screening technologies on biomarker discovery will be highlighted and how new or improved technologies may allow the discovery of either diagnostic biomarkers for schizophrenia or biomarkers that will be useful in determining appropriate treatments for people with the disorder. History tells those involved in biomarker research that the discovery and validation of useful biomarkers is a long process and current progress must always be viewed in that light. However, the approval of the first biomarker screen with some value in predicting responsiveness to antipsychotic drugs suggests that biomarkers can be identified and that these biomarkers that will be useful in diagnosing and treating people with schizophrenia.
Immune dysregulation among students exposed to exam stress and its mitigation by mindfulness training: findings from an exploratory randomised trial.
Creators: name: Turner, Lorinda
name: Galante, Julieta
name: Vainre, Maris
name: Stochl, Jan
name: Dufour, Géraldine
name: Jones, Peter B
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Psychological distress persisting for weeks or more promotes pro-inflammatory immune dysregulation, a risk factor for a range of chronic diseases. We have recently shown that mindfulness training reduces distress among university students. Here we present an exploratory trial to study immune dysregulation in a cohort of students who were exposed to progressively greater stress as the exam period approached, and to explore whether mindfulness training mitigated this dysregulation. Healthy University of Cambridge students were randomised to join an 8-week mindfulness course (N = 27), or to mental health support as usual (N = 27). Psychological distress, immune cell proportions, cytokines, CRP and serum cortisol were measured at baseline and during the exam period. Increased distress was associated with statistically significant increases in the proportion of B cells, regardless of trial arm (*p = 0.027). There were no other associations between any of the measured parameters, distress or mindfulness. Our finding that the proportion of B cells increases with psychological distress supports the findings of other studies. However, we found no evidence that mindfulness training is able to buffer the effects of psychological distress on healthy participants' immune system. In order to detect these effects, should they exist, larger randomised trials will be required.
Intention to Vaccinate Against the Novel 2019 Coronavirus Disease: The Role of Health Locus of Control and Religiosity
Creators: name: Olagoke, Ayokunle A
name: Olagoke, Olakanmi O
name: Hughes, Ashley
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: The urgency to develop a vaccine against the 2019 coronavirus (COVID-19) has waxed stronger in speed, scale, and scope. However, wisdom dictates that we take a vantage position and start to examine the demographic predictors of COVID-19 vaccine hesitancy. The objective of this study was to examine the role of health locus of control (HLOC) in the relationship between religiosity and COVID-19 vaccination intention. In a cross-sectional survey (N = 501), we found a significantly negative association between religiosity and COVID-19 vaccination intention. This relationship was partially mediated by external HLOC. Collaborative efforts with religious institutions may influence COVID-19 vaccine uptake.
Biomarkers in schizophrenia: a focus on blood based diagnostics and theranostics
Creators: name: Lai, Chi-Yu
name: Scarr, Elizabeth
name: Udawela, Madhara
name: Everall, Ian
name: Chen, Weijian
name: Dean, Brian
Publisher: name: Swinburne
Year: 2024

description: Identifying biomarkers that can be used as diagnostics or predictors of treatment response (theranostics) in people with schizophrenia (Sz) will be an important step towards being able to provide personalized treatment. Findings from the studies in brain tissue have not yet been translated into biomarkers that are practical in clinical use because brain biopsies are not acceptable and neuroimaging techniques are expensive and the results are inconclusive. Thus, in recent years, there has been search for blood-based biomarkers for Sz as a valid alternative. Although there are some encouraging preliminary data to support the notion of peripheral biomarkers for Sz, it must be acknowledged that Sz is a complex and heterogeneous disorder which needs to be further dissected into subtype using biological based and clinical markers. The scope of this review is to critically examine published blood-based biomarker of Sz, focusing on possible uses for diagnosis, treatment response, or their relationship with schizophrenia-associated phenotype. We sorted the studies into six categories which include: (1) brain-derived neurotrophic factor; (2) inflammation and immune function; (3) neurochemistry; (4) oxidative stress response and metabolism; (5) epigenetics and microRNA; and (6) transcriptome and proteome studies. This review also summarized the molecules which have been conclusively reported as potential blood-based biomarkers for Sz in different blood cell types. Finally, we further discusses the pitfall of current blood-based studies and suggest that a prediction model-based, Sz specific, blood oriented study design as well as standardize blood collection conditions would be useful for Sz biomarker development.
Evidence for impaired glucose metabolism in the striatum obtained postmortem from subjects with schizophrenia
Creators: name: Dean, Brian
name: Thomas, Neil
name: Scarr, E.
name: Udawela, M.
Publisher: name: Swinburne
Year: 2024

description: Studies using central nervous system tissue obtained postmortem suggest pathways involved in energy and metabolism contribute to the pathophysiology of schizophrenia; neuroimaging studies suggesting glucose metabolism is particularly affected in the striatum. To gain information on the status of pathways involved in glucose metabolism in the striatum, we measured levels of glucose, pyruvate, acetyl-CoA and lactate as well as the β subunit of pyruvate dehydrogenase, a rate limiting enzyme, in the postmortem tissue from subjects with schizophrenia and age/sex-matched controls. The subjects with schizophrenia were made up of two subgroups, which could be divided because they either had (muscarinic receptor deficit schizophrenia (MRDS)), or did not have (non-MRDS), a marked deficit in cortical muscarinic receptors. Compared to controls, levels of β subunit of pyruvate dehydrogenase were lower (Δ mean=−20%) and levels of pyruvate (Δ mean=+47%) and lactate (Δ mean=+15%) were significantly higher in the striatum from subjects with schizophrenia. Notably, in subjects with non-MRDS, striatal levels of β subunit of pyruvate dehydrogenase were lower (Δ mean=−29%), whereas levels of pyruvate (Δ mean=−66%), acetyl-CoA (Δ mean=−28%) and glucose (Δ mean=-27%) were higher, whereas levels of lactate (Δ mean=+17%) were higher in MRDS. Finally, discriminate analyses using levels the β subunit of pyruvate dehydrogenase and glucose, or better still, β subunit of pyruvate dehydrogenase and glucose in combination with pyruvate, lactate or acetyl-CoA could separate subjects with non-MRDS from controls with high levels of specificity (up to 93%) and selectivity (up to 91%). Our data show the benefit of being able to study defined subgroups within the syndrome of schizophrenia as such an approach has revealed that changes in glucose metabolism may be a significant contributor to the pathophysiology of non-MRDS.
The Relationship Between Happiness and Depression Among Senior High School Students Amidst the COVID-19 Pandemic
Creators: name: Padilla, Ritz
name: Education, Psychology and
Publisher: name: figshare
Year: 2022
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology
subject: Developmental and Educational Psychology
subject: Education
subject: 160809 Sociology of Education
subject: FOS: Sociology

description: The current situation amidst the pandemic has caused such negativities to people, especially among students. It has affected the well-being and happiness that everyone experiences. In, on the other hand, students who were enrolled amidst the pandemic were more likely to experience mental exhaustion such as anxiety and depression, as this current situation limits and affect their academic performances and the level of happiness they feel. This study investigates the relationship between happiness and depression among senior high school students here in the Philippines. The findings revealed a significant correlation between happiness and depression (r=0.041).
i2b2 Webclient Developers Guide
Creators: name: Benik, Nick
name: Weber, Griffin M
Publisher: name: figshare
Year: 2014
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications
subject: Computer Software
subject: FOS: Computer and information sciences
subject: 80309 Software Engineering
subject: Data Format
subject: Applied Computer Science

description: I found this forgotten document written back in 2010 for i2b2 Webclient v1.4. It is unfinished in that it probably contains typos, some missing references and grammar errors. Regardless, It should still be technically relevent to the latest i2b2 version. It contains a very detailed description of how the i2b2 webclient works and provides an in-depth, technical walk-through for the 3 example plugins that come with the default download. I may update/correct when I get some free time.
The conserved mosaic prophage protein paratox inhibits the natural competence regulator ComR in Streptococcus
Creators: name: Mashburn-Warren, Lauren
name: Goodman, Steven D
name: Federle, Michael
name: Prehna, Gerd
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: Horizontal gene transfer is an important means of bacterial evolution. This includes natural genetic transformation, where bacterial cells become "competent" and DNA is acquired from the extracellular environment. Natural competence in many species of Streptococcus, is regulated by quorum sensing via the ComRS receptor-signal pair. The ComR-XIP (mature ComS peptide) complex induces expression of the alternative sigma factor SigX, which targets RNA polymerase to CIN-box promoters to activate genes involved in DNA uptake and recombination. In addition, the widely distributed Streptococcus prophage gene paratox (prx) also contains a CIN-box, and here we demonstrate it to be transcriptionally activated by XIP. In vitro experiments demonstrate that Prx binds ComR directly and prevents the ComR-XIP complex from interacting with DNA. Mutations of prx in vivo caused increased expression of the late competence gene ssb when induced with XIP as compared to wild-type, and Prx orthologues are able to inhibit ComR activation by XIP in a reporter strain which lacks an endogenous prx. Additionally, an X-ray crystal structure of Prx reveals a unique fold that implies a novel molecular mechanism to inhibit ComR. Overall, our results suggest Prx functions to inhibit the acquisition of new DNA by Streptococcus.
title: Die Konsultation der EU-Kommission zum Investitionsschutz: Was lernen wir daraus über die TTIP-Verhandlungen?
Creators: name: Krajewski, Markus
Publisher: name: Fachinformationsdienst für internationale und interdisziplinäre Rechtsforschung
Year: 2014
Subjects: subject: 342

description: Verfassungsblog: On Matters Constitutional
The Self-Efficacy and Loneliness of College Students Amidst the COVID-19 Pandemic
Creators: name: Ramos, Joerell
name: Education, Psychology and
Publisher: name: figshare
Year: 2022
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology
subject: Developmental and Educational Psychology
subject: Education
subject: 160809 Sociology of Education
subject: FOS: Sociology

description: The current pandemic has caused the education system to adapt especially to a new way of learning, namely online learning. Furthermore, Online learning set-up results to students learning within their homes and cause them to isolate themselves, avoid social contact, and lessen the interaction within their friends, family, and other love ones. Although students still achieve academic excellence, learning from home can have an effect to their psychological health and to their self-efficiency. One of these is Loneliness, the more a student feels to be lonely the higher its risk in having low self-efficacy. In that manner, this study observes the relationship of Loneliness to Self-Efficacy of college students living here in the Philippines. The statistical findings reveals that there is a significant relationship between Loneliness and Self-Efficacy (r=.171).
Methods for PRMT3 cellular assay
Creators: name: Szewczyk, Magdalena
Publisher: name: Zenodo
Year: 2020
Subjects: PRMT3, protein arginine methyltransferase, arginine methylation, histone H4R3 asymmetric dimethylation, SGC707

description: Methods for PRMT3 cellular assay posted on openlabnotebook.org
Evaluating the potential of natural curcumin for oxidative stability of soybean oil
Creators: name: Naeeme Eshghi
name: Asnaashari, Maryam
name: Khodaparast, Mohammad Hossein Haddad
name: Hosseini, Fereshteh
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: The active substance of turmeric rhizome (curcumin) was extracted and identified with TLC and NMR. To evaluate the antioxidant efficiency of different concentrations of curcumin (120, 160 and 200 ppm) compared with tert-butylhydroquinone (TBHQ) (120 ppm) and α-tocopherol (200 ppm) at two different temperatures (25°C and 55°C) under dark and light conditions during 90 days, the soybean oil with no added antioxidant was used as a food model, and its fatty acids profile was determined by GC. Results indicated that increasing concentration of curcumin leads to significantly decreased oxidation rates. The soybean oil containing curcumin at 25°C in darkness with the lowest rate of increased peroxide value indicated the same antioxidant activity with α-tocopherol and TBHQ. Moreover, the results of acid value and iodine value indicated that samples with curcumin were more effective in preventing oxidation at both temperatures compared with control. However, light did not have any significant effect.
Isoform specific differences in phospholipase C beta 1 expression in the prefrontal cortex in schizophrenia and suicide
Creators: name: Udawela, M.
name: Scarr, E.
name: Boer, S.
name: Um, J. Y.
name: Hannan, A. J.
name: McOmish, C.
name: Felder, C. C.
name: Thomas, E. A.
name: Dean, Brian
Publisher: name: Swinburne
Year: 2024

description: Our previous study demonstrated that phospholipase C beta 1 mRNA was down-regulated in Brodmann’s area 46 from subjects with schizophrenia. However, phospholipase C beta 1 protein has also been shown to be lower in Brodmann’s area 8 and 9 from teenage suicide subjects, creating a potential confound in interpreting the findings in schizophrenia due to the high suicide rate associated with this disorder. To begin to reconcile and consolidate these findings, in this study, we measured mRNA and protein levels of phospholipase C beta 1 variants a and b in Brodmann’s area 46 and Brodmann’s area 9 from subjects with schizophrenia, many of whom were suicide completers, and determined the diagnostic specificity of observed findings. Consistent with our previous study, levels of phospholipase C beta 1 a and b mRNA, but not protein, were lower in Brodmann’s area 46 from subjects with schizophrenia. In Brodmann’s area 9, phospholipase C beta 1a protein levels were lower in subjects with schizophrenia, while phospholipase C beta 1b mRNA was higher and protein was lower in those that had died of suicide. Altered protein levels in Brodmann’s area 9 appeared to be diagnostically specific, as we did not detect these changes in subjects with bipolar disorder, major depressive disorder or suicide completers with no diagnosis of mental illness. We further assessed the relationship between phospholipase C beta 1 and levels of muscarinic receptors (CHRMs) that signal through this protein, in both human and Chrm knockout mouse central nervous system tissue, and found no strong relationship between the two. Understanding central nervous system differences in downstream effector pathways in schizophrenia may lead to improved treatment strategies and help to identify those at risk of suicide.