cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: “It’s not so much what you know, it’s who you know”
title: a look into rural teachers’ perspectives in mentoring student aspirations
titleType: Subtitle
Creators: name: Sung, Taylor
Publisher: name: University of Iowa
Year: 2023
Subjects: institutional agents
Iowa
rural
student aspirations
symbolic boundaries
teachers
public abstract

description: The aim of this thesis is to provide analysis on the mentorship role rural high school teachers embody as institutional agents in geographically distinct high school settings in Iowa. This study will supplement existing literature on student-teacher relationships, future-oriented resources at rural high schools, and the multiplex roles of rural teachers. The thesis analyzes rural high school teachers’ role as an institutional agent in setting symbolic boundaries to determine their responsibility in mentoring students’ career and educational goals for the future. By assessing how rural high school teachers perceive their role as an institutional agent in mentoring student aspirations, this study analyzes respondents’ definitions of their roles in supporting high school students’ aspirations, as well as how teachers utilize symbolic boundaries to determine who receives career and educational resources. Furthermore, this thesis aims to uncover rural high school teachers’ perceptions of students’ needs in career and educational support. Through qualitative, semi-structured interviews, this study reveals that rural high school teachers perceive their mentorship roles differently depending on existing resources at local high schools; respondents overwhelming distinguished high-achieving students involved in school extracurriculars as the primary beneficiaries of their mentorship roles in providing concrete resources and validation through verbal and non-verbal cues. Additionally, respondents pointed to the need to implement more structured resources in local high schools to better support all students’ educational and career developmental needs.
Homoarginine - A prognostic indicator in adolescents and adults with complex congenital heart disease?
Creators: name: Raedle-Hurst, Tanja
name: Mueller, Marieke
name: Meinitzer, Andreas
name: Maerz, Winfried
name: Dschietzig, Thomas
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten

description: Background: Homoarginine (hArg) has been shown to be of prognostic value in patients with chronic left heart failure. The present study aims to assess the clinical utility and prognostic value of hArg levels in patients with complex congenital heart disease (CHD). Methods: Plasma hArg levels were measured in 143 patients with complex CHD and compared to clinical status, echocardiographic and laboratory parameters as well as the occurrence of adverse cardiac events. Results: Median hArg levels were 1.5 μmol/l in CHD patients as compared to 1.70 μmol/l in healthy controls (p = 0.051). Median hArg levels were lowest in patients with Fontan palliation (1.27 μmol/l) and Eisenmenger physiology (0.99 μmol/l) and decreased with the severity of adverse cardiac events with lowest values found in patients prior to death or overt heart failure (0.89 μmol/l). According to ROC analysis, the most important predictors of adverse cardiac events were hArg levels (AUC 0.837, p<0.001, CI 0.726–0.947), NYHA class (AUC 0.800, p<0.001, CI 0.672–0.928) and NT-proBNP levels (AUC 0.780, p<0.001, CI 0.669–0.891). The occurrence of overt heart failure or death due to progressive heart failure were best predicted by NYHA class (AUC 0.945, p<0.001, CI 0.898–0.992), hArg levels (AUC 0.911, p<0.001, CI 0.850–0.971) and NT-proBNP levels (AUC 0.877, p<0.001, CI 0.791–0.962), respectively. Conclusion: In patients with complex CHD, hArg levels can predict adverse cardiac events as reliably as or even better than NT-proBNP levels and thus might be of prognostic value in this subset of patients.
Additional file 8 of Identification of a novel ERF gene, TaERF8, associated with plant height and yield in wheat
Creators: name: Zhang, Lei
name: Liu, Pan
name: Wu, Jing
name: Linyi Qiao
name: Guangyao Zhao
name: Jizeng Jia
name: Lifeng Gao
name: Jianming Wang
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 8: Table S6. The frequencies of TaERF8-2B allelic variation in sample set 3.
The Making & Unmaking of East-West Link
Creators: name: Murphy, James C.
Publisher: name: Swinburne
Year: 2024

description: This thesis looks at an infamous case of infrastructure policymaking in Australia: Victoria's East-West Link. A multi-billion-dollar road tunnel, East-West was bitterly contested, subject of fierce debate, protests, court challenges and political brinkmanship, culminating in the project's cancellation in 2015. All told the fiasco resulted in the wasting of over a billion dollars of public money. This thesis asks where East-West Link came from and what went wrong, seeking insights from three different theoretical approaches, and in the process investigating the state of policymaking in Victoria and polities like it.
title: How to prevent the detrimental effects of two months of bed-rest on muscle, bone and cardiovascular system
title: an RCT
titleType: Subtitle
Creators: name: Kramer, Andreas
name: Gollhofer, Albert
name: Armbrecht, Gabriele
name: Felsenberg, Dieter
name: Gruber, Markus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: AgeingBone
subject: Cardiovascular diseases
subject: Medical research
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Physical inactivity leads to a deconditioning of the skeletal, neuromuscular and cardiovascular system. It can lead to impaired quality of life, loss of autonomy, falls and fractures. Regular exercise would be a logical remedy, but the generally recommended high-volume endurance and strength training programs require a lot of time and equipment. In this randomized controlled study with 23 healthy participants, we established that a short, intensive jump training program can prevent the large musculoskeletal and cardiovascular deconditioning effects caused by two months of physical inactivity during bed rest, particularly the loss of bone mineral mass and density, lean muscle mass, maximal leg strength and peak oxygen uptake. The jump training group showed no significant changes with respect to these indicators of musculoskeletal and cardiovascular health after 60 days of bed rest, whereas the control group exhibited substantial losses: up to −2.6% in tibial bone mineral content and density, −5% in leg lean mass, −40% in maximal knee extension torque and −29% in peak oxygen uptake. Consequently, we recommend jump training as a very time-efficient and effective type of exercise for astronauts on long-term space missions, the elderly and sedentary populations in general.
Fallstudie Universitätsspital Basel
Creators: name: Tanner, Christian
Publisher: name: Hanser
Year: 2004
Subjects: subject: Case Study
subject: EBPP
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Das Universitätsspital Basel anerkennt, dass die ausschliessliche Ausrichtung auf das Patientenwohl nicht ausreicht, um dem zunehmenden Kostendruck und Wettbewerb sowie den kritischen Ansprüchen der Gesellschaft zu begegnen. Durch eine professionelle Logistik sollen effiziente Prozesse und eine hoch stehende interne und externe Dienstleistung unter gesetzeskonformen Rahmenbedingungen gewährleistet werden. Das Universitätsspital will die Potenziale der Informationstechnologien konsequent und gewinnbringend nutzen und diesbezüglich in der Schweiz eine Schrittmacherfunktion einnehmen. Die elektronische Rechnungsabwicklung mit Lieferanten ist ein wichtiger Mosaikstein in diesen Bestrebungen. Die ohnehin schon schlanke, zentralisierte Rechnungsprüfung gewinnt dadurch noch weiter an Effizienz und Qualität.
Spinning a tale: English translations and adaptations of "La Belle au bois dormant" from the Enlightenment to the Magic Kingdom.
Creators: name: Gerald, Amy.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Literature, Germanic.

description: The objective of this thesis is to describe the influence that changes in the target environment have on translations and adaptations. Two translations and two adaptations, belonging to different cultures and eras, of the fairy tale La Belle au bois dormant (1697) by Charles Perrault have been selected for contexualization and comparison. For each of the four target texts, I reconstruct the relevant historical, literary and translation context and describe the intended audience and purpose, drawing parallels between these external factors and the choices made by the translators and adapters in their respective texts. A discussion of Descriptive Translation Studies, polysystem theory, norm theory, the notions governing rewriting, and Skopostheory provides a theoretical framework for the thesis. The analysis is divided into three chapters. In the first I situate the source text within its genre and historical context and outline the origins of the tale, the life of its author and how the tale reflects both its humble roots and the aristocratic audience to whom it was addressed. The second chapter deals with two English translations: The Sleeping Beauty in the Wood (1729) by Robert Samber and The Sleeping Beauty (1957) by Geoffrey Brereton. Each of the translations is presented in relation to its era and a three-way comparison between the source text, the translations and their contexts brings forth some possible reasons for the differences in the target texts. The final chapter looks at two famous adaptations of this well-known tale, the Brothers Grimms' Dornroschen (Briar Rose) (1812) and Walt Disney's Sleeping Beauty (1959), and demonstrates how these authors were influenced by various factors of their respective eras.
Application of the hydroxy-directed Diels-Alder reaction toward the total synthesis of havellockate
Creators: name: Beingessner, Rachel Lynn
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Chemistry, Organic.

description: This thesis describes our efforts into the synthesis of a natural product named havellockate, which was isolated from a soft coral in the Indian Ocean. This highly compact diterpenoid contains a cis- fused hydrindane core that bears eight stereogenic centers as well as a seco- and spiro-lactone. The early part of this thesis details the application of the hydroxy-directed Diels-Alder reaction to provide rapid entry into the core of the molecule. The subsequent chapters describe the four approaches that were investigated for installing the side-chain of this natural product which contains a challenging stereogenic center. These approaches which include two different Claisen rearrangements, a Diels-Alder reaction as well as a cuprate addition onto an alpha,beta-unsaturated carbonyl compound are presented in detail.
Using consumer neuroscience to help save lives
Creators: name: Harris, Joanne
Publisher: name: Swinburne
Year: 2024

description: Interdisciplinary consumer neuroscience research. Investigated the advertising effectiveness of action/emotion/challenge and positive emotion-based strategies used for successful digital/social media public health/social cause marketing communications. Contributes to the academic consumer neuroscience, social media and advertising effectiveness literature and future development of successful health/social cause marketing campaigns which may reduce ineffectual marketing expenditure and potentially help save lives.
Fallstudie Stadt Lörrach - City goes B2B
Creators: name: Treffert, Jürgen
name: Wölfle, Ralf
Publisher: name: Hanser
Year: 2002
Subjects: subject: E-Business
subject: E-Procurement
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Die Stadt Lörrach hat einen externen Dienstleister mit dem Betrieb einer Beschaffungslösung für regelmässige Bedarfsgüter beauftragt. Die Bedarfsträger aus Verwaltungen, Schulen, Bädern und weiteren kommunalen Einrichtungen können orts-unabhängig via Browser und Internet auf die jeweils für sie vereinbarten Sortimente zugreifen und bei den Lieferanten gebündelte Bestellungen auslösen. Die in der Region von einem Start-up-Unternehmen betriebene und am regionalen Steinbeis-Transferzentrum programmierte Lösung zeichnet sich durch ihr innovatives und pragmatisches Vorgehen aus.
The association of chronic physical illness and eating attitudes in school-aged children: A secondary analysis based on a community survey of the epidemiology and risk factors for eating and mood disorders in children.
Creators: name: Kierulf, Jacqueline C.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Health Sciences, Mental Health.

description: Children with chronic physical illness have twice the risk of psychosocial maladjustment as healthy children. One specific aspect of mental functioning is abnormal eating attitudes, hypothesized to be an early stage of an eating disorder. To date, there has been no study of the association of a variety of physical chronic illnesses with a specific psychiatric syndrome in a diagnostically heterogeneous population, comparing chronically ill children with healthy children. This study examined the association between chronic illness and eating attitudes in a population of school children from Western Quebec. A checklist of chronic medical conditions was added to the parent questionnaire in order to determine presence of chronic illness. There were two objectives of this thesis. The first objective was to determine whether chronic illness was associated with eating attitudes in children as measured by the Eating Attitudes Test. The second study objective was to determine whether there was a meaningful group difference in othcr psychometric scores of depression, family functioning and stress between children with a chronic illness and children without a chronic illness. (Abstract shortened by UMI.)
ICT and Innovation in Small Companies
Creators: name: Schubert, Petra
name: Fisher, Julie
name: Leimstoll, Uwe
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2007
Subjects: subject: ICT
subject: IKT
subject: Informatik
subject: Literature Review
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: The small business sector is very important to most economies generating significant wealth and employment. It has generally been accepted that small business owners are less likely to embrace innovation and less likely to have a well-defined business strategy. Yet for companies to grow and continue to be successful innovation is critical. Given the importance of this sector there is a need for governments and policy makers to understand innovation in small business particularly in terms of ICT implementation and use in order to formulate appropriate programs and policies. There have been few studies reported in the literature however, that have looked at innovation in the small business sector. This study investigated small Swiss businesses with 10 to 49 employees. A survey of 389 small businesses found that most see themselves as innovative and most use IT to support innovation.
Developing a Framework for Understanding Adolescent Behaviour on Social Media: A Sequential Exploratory Mixed Methods Study
Creators: name: La Sala, Louise Anne
Publisher: name: Swinburne
Year: 2024

description: The purpose of this thesis was to explore adolescent identity development in the context of social media. This thesis focused on the social and emotional influences guiding the choices young people make about social media, the types of behaviour associated with social media usage, how adolescents interpret feedback received online, and how this relates to emotional regulation and expression. Drawing on the literature presented in this thesis, an exploratory model of social media behaviour is proposed as a framework for understanding adolescent social media behaviour.
Infographic: How to Recognize Misinformation
Creators: name: Domgaard, Shawn K.
name: Austin, Erica W.
Publisher: name: Edward R. Murrow Center for Media and Health Promotion Research, Edward R. Murrow College of Communication, Washington State University
Year: 2022
Subjects: Communications

description: This infographic provides a guide to help the user find accurate and credible messages in the media to make their own best decisions. There are 4 parts to the process, but they do not need to be done in any specific order.
Fallstudie Otto Fischer AG: Papierloser Warenfluss durch mobile Geräte
Creators: name: Hügli, Raphael
Publisher: name: Hanser
Year: 2006
Subjects: subject: Business Software
subject: Case Study
subject: E-Business
subject: EDI
subject: ERP-Systeme
subject: Geschäftsmodell
subject: Integration
subject: Strategie
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Die Otto Fischer AG vertreibt elektrotechnische Produkte an professionelle Elektroinstallateure. Der Kommissionierung fällt in diesem Geschäft eine strategische Bedeutung zu. Mit dem Einsatz von mobilen Datenerfassungsgeräten konnte das Unternehmen seine Produktivität und Flexibilität erhöhen. Voraus ging ein Projekt, das die Aufnahme und Anpassung der internen Prozesse erforderte. Das Resultat ist ein papierloser Warenfluss von der Kundenbestellung bis zur Warenauslieferung an den Kunden. Die Fallstudie beleuchtet Hintergründe und Erfahrungen dieser Systemeinführung, wobei für den Bereich Kommissionierung detailliert auf Einzelheiten eingegangen wird.
New GPU-accelerated free energy simulation methods in AMBER
Creators: name: Tsai, Hsu-Chun
Publisher: name: No Publisher Supplied
Year: 2024

description: The drug development process, spanning over 10 years and costing more than $1 billion, involves complex stages from discovery to clinical trials. Structure-based drug design (SBDD), particularly utilizing computational methods, and in particular, molecular simulations, plays a crucial role in streamlining early phases, predicting binding affinity, and aiding lead compound optimization. Despite recent advancements, challenges persist in achieving robust and affordable tools for high-precision free energy predictions in drug discovery applications. In this dissertation, several improved methods have been developed for accurate and robust alchemical free energy simulations, and apply these methods to the prediction of protein-ligand binding affinities of drug targets. Chapter 2 outlines the general background and approaches for absolute/relative free energy calculations. Chapter 3 provides the comparison of the consistency of alchemical transformations of relative and absolute hydration free energies via the λ-dependence of 1-4 van der Waals and electrostatic interactions between the softcore and common core atoms for general cases. In Chapter 4, the new softcore potential form is developed which combined with smoothly transforming nonlinear λ weights for mixing specific potential energy terms, along with flexible λ-scheduling features, to enable robust and stable alchemical transformation pathways. Chapter 5 presents the improvement of the precision of RBFE calculations with an alchemical enhanced sampling approach (ACES) on a large and diverse set of proteins and small moleucle ligands. Chapter 6 illustrates the combination of ACES and the λ-dependent Boresch restraint, and applied on the core-hopping in drug discovery.
Characterizing Effective Familial Communication of Hereditary Breast and Ovarian Cancer Risk: Longitudinal Reflections of ConnectMyVariant Participants
Creators: name: Clark, Rebecca L
Publisher: name: Brandeis University
Year: 2025
Subjects: extended relative
family communication
hereditary cancer
risk disclosure
successful communication
timeline

description: Managing the burden of a high-risk hereditary cancer genetic test result, probands are also often tasked with communicating cancer risk information to their family members. Predictably, this duty to warn is associated with emotional and logistical complications. To improve support and outcomes for these patients and their family members, this study aimed to deepen understanding of the hereditary cancer risk communication process. We conducted semi-structured interviews with ConnectMyVariant users that had a familial pathogenic variant in genes associated with hereditary breast and ovarian cancer. During the interviews, the participant and researcher collaboratively developed a communication timeline to represent the longitudinal experience of the participant. We found clear evidence that hereditary breast and ovarian cancer risk communication occurs through successive, ongoing interactions. Follow-up and ongoing communication events preceded 40.8% of the total familial testing reported, corresponding with a correlation coefficient of 0.44. Additionally, we characterized patterns unique to extended family communication. Lastly, our findings provide insight to how probands assess hereditary risk communication. Further validation of these results will inform probands and genetic health professionals of effective patterns when sharing hereditary cancer risk information.
The Federation of Asian Chemical Societies: Forty years on
Creators: name: Spurling, Thomas
name: Webb, John
Publisher: name: Swinburne
Year: 2024

description: In the 1970s UNESCO and many national aid agencies understood the important role that the application of chemistry had in developing the social, economic and environmental wellbeing of nations. UNESCO also understood the vital role that professional societies play in fostering chemical capability and helped organise the formation of the Federation of Asian Chemical Societies (FACS). In 1980 our region contributed only 19% of world chemistry papers. The task of the FACS was, through networks, working groups and collaboration, to foster the development of chemistry in the region. This was highly successful. In 2018 our region contributed nearly 60% of all the world’s chemistry papers. We are the epicentre of world chemistry. However, chemical capability is still low in many of our member countries. The FACS now has two tasks. Catering for the high performing chemists in the region while still fostering the development of chemistry in those countries still developing.
Modeling Contentious Politics: The case of civil strife and radicalization in the Middle East and North Africa
Creators: name: Dacrema, Eugenio
Publisher: name: Universit� degli studi di Trento
Year: 2019

description: This dissertation introduces instruments of agent-based modeling into the literature of contentious politics and broadens the application of game theory and quantitative analytical tools in this field. This work is composed of three working papers that focus specifically on the following topics:
? In the first paper, I present a dynamic agent-based model encompassing the most important and up-to-date findings in the field of contentious politics and synthesize them within one homogeneous theoretical framework. After providing the theoretical description of the model, I run computer simulations to test the concrete functioning of the theoretical dynamics within it and find consistent analogies with real-world events.
? In the second paper, I analyze the influence of socioeconomic inequality on individuals? participation in contentious episodes. I do so by analyzing the socioeconomic trends that characterized three Arab countries ? Tunisia, Egypt, and Jordan ? during the decade that preceded the 2011 uprisings and the social characteristics of those who participated in the subsequent protests, as they emerged in the 2011 wave of the Arab Barometer surveys.
? In the third paper, I provide an overview of the relatively limited literature that applies the principles of game theory to the study of political or religious radicalization. After describing its main findings, I suggest how Rapoport?s seminal work on the historical ?waves of terrorism? can be treated dynamically through some fundamental game-theoretic principles such as coordination problems, Thomas Shelling?s focal points and in the solutions proposed by the literature on correlated equilibria.
title: Effectiveness of app-based relaxation for patients with chronic low back pain (Relaxback) and chronic neck pain (Relaxneck)
title: study protocol for two randomized pragmatic trials
titleType: Subtitle
Creators: name: Blödt, Susanne
name: Pach, Daniel
name: Roll, Stephanie
name: Witt, Claudia M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2014
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Chronic low back pain (LBP) and neck pain (NP) are highly prevalent conditions resulting in high economic costs. Treatment guidelines recommend relaxation techniques, such as progressive muscle relaxation, as adjuvant therapies. Self-care interventions could have the potential to reduce costs in the health care system, but their effectiveness, especially in a usual care setting, is unclear. The aim of these two pragmatic randomized studies is to evaluate whether an additional app-delivered relaxation is more effective in the reduction of chronic LBP or NP than usual care alone. Methods/design Each pragmatic randomized two-armed study aims to include a total of 220 patients aged 18 to 65 years with chronic (>12 weeks) LBP or NP and an average pain intensity of ≥ 4 on a numeric rating scale (NRS) in the 7 days before recruitment. The participants will be randomized into an intervention and a usual care group. The intervention group will be instructed to practice one of these 3 relaxation techniques on at least 5 days/week for 15 minutes/day over a period of 6 months starting on the day of randomization: autogenic training, mindfulness meditation, or guided imagery. Instructions and exercises will be provided using a smartphone app, baseline information will be collected using paper and pencil. Follow-up information (daily, weekly, and after 3 and 6 months) will be collected using electronic diaries and questionnaires included in the app. The primary outcome measure will be the mean LBP or NP intensity during the first 3 months of intervention based on daily pain intensity measurements on a NRS (0 = no pain, 10 = worst possible pain). The secondary outcome parameters will include the mean pain intensity during the first 6 months after randomization based on daily measurements, the mean pain intensity measured weekly as the average pain intensity of the previous 7 days over 3 and 6 months, pain acceptance, ‘LBP- and NP-related’ stress, sick leave days, pain medication intake, adherence, suspected adverse reaction, and serious adverse events. Discussion The designed studies reflect a usual self- care setting and will provide evidence on a pragmatic self-care intervention that is easy to combine with care provided by medical professionals.
Pixel um Pixel: Favicons erobern das Web
Creators: name: Bendel, Oliver
Publisher: name: University Press
Year: 2009
Subjects: subject: Internet
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Favicons sind im Web weitverbreitet und in der wissenschaftlichen Literatur kaum existent. Es handelt sich um Icons, die unter anderem die Lesezeichenliste und Adresszeile des Browsers zieren. Aber zieren und schmücken sie wirklich oder haben sie vielmehr den blossen Zweck, die Wiedererkennbarkeit der Website zu unterstützen? Und in die entgegengesetzte Richtung gefragt: Kann man sie nicht auch völlig unabhängig von ihrem technischen Raum betrachten, als eine neue Form der minimalistischen Kunst und des reduzierten Grafikdesigns? Der Beitrag von Oliver Bendel versucht diese Spannweite auszumessen und den unterschätzten Bildern ihren Platz in der Medienkunst zuzuweisen.
Issues in large scale collaborative virtual environments.
Creators: name: De Oliveira, Jauvane Cavalcante.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Engineering, Electronics and Electrical.

description: Collaborative Virtual Environments (CVE) are virtual reality spaces that enable participants to collaborate and share objects, as if physically present in the same place. CVE concepts have been used in many systems in the past few years. Applications of such technology range from military combat simulations to various civilian commercial applications. These collaboration spaces have strict performance requirements. Today, there are many such systems developed specifically for collaboration. At the same time, some relatively new standards that address multiuser virtual environments and shared spaces have become available; however, most of these standards have been developed assuming that a small number of users would be interacting at a given time. The architectures available today provide support for a modest number of users but they fail if too many users are "present" together in a small "space" in the Virtual World. In this work, we first evaluate the currently available standards for the case of a very large number of users. An Adaptive Hybrid Architecture for VEry Large Virtual EnvironmenTs (VELVET) is then introduced. VELVET allows a large number of users to interact in a CVE. It also supports small groups of users, but it is in the large environment case that shows its greatest potential. VELVET introduces a novel adaptive area of interest management, which supports heterogeneity amongst the various participants. That allows users in a supercomputer with a high-speed networking connection to successfully collaborate with others in not-so-powerful systems behind a slow dial-up connection. In order to make a Collaborative Virtual Environment more interesting to users, it is possible to "stitch" together copies of areas which users may have interest in from one Virtual World into another. This procedure augments the physical size of a Virtual World, and creates a potentially larger number of users within the World, first because of the "embedding" and second since the added attractions may work as an incentive for some more users to join the "embedded" World. On the other hand this procedure brings up a series of problems related with consistency, which are also addressed in the thesis. We introduce a methodology which ensures that all copies of a given area of a World are kept consistent among them, as well as with the original world. We also apply this methodology in VELVET, as well as in other Architectures. Additionally, we introduce other approaches to be used when a less strict consistency model is sufficient.
Deep learning methods for satellite image timeseries
Creators: name: Tarasiou, Michail
Publisher: name: Imperial College London
Year: 2023

description: The practice of Earth Observation (EO) plays a critical role in monitoring human activities and their environmental impacts through remote sensing technologies. This is crucial for designing interventions that enhance societal prosperity and resilience. Recent advancements in Deep Neural Networks (DNNs), coupled with increasingly available EO data, present a unique opportunity for improving future production systems. However, current research crucially overlooks unique attributes of satellite imagery and suffers from a lack of publicly accessible, large-scale annotated datasets. This PhD thesis explores the potential of automating EO tasks within a DNN framework. To this end, several key aspects of the problem are explored. Firstly, a dataset generation tool is introduced that standardizes and simplifies the processing of Sentinel-2 data for DNN applications. DeepSatData is designed to be lightweight and can be adapted to meet various research needs through the Python library ecosystem. Furthermore, the Temporo-Spatial Vision Transformer (TSViT), the first fully-attentional model optimized for processing Satellite Image Time Series (SITS), is introduced. TSViT employs input factorization and specific inductive biases that improve its discriminative capability, substantially outperforming existing models in large-scale land cover recognition benchmarks. To take advantage of large scale SITS data readily available, EmbeddingEarth, a self-supervised pre-training method, is developed to boost the performance of land cover classification at the pixel level. This method allows models, pre-trained in different regions, to be effectively fine-tuned on new areas, indicating the potential for developing foundational models for EO. Lastly, a fully supervised pre-training method is introduced, targeting performance improvements at object boundaries for semantic segmentation. Context-Self Contrastive Pre-training, using no additional data, enhances the performance of all state-of-the-art networks on land cover recognition, particularly at fine-grain boundaries.
Thanik Lertcharnrit photo with colleagues at Silpakorn University, Bangkok, Thailand
Creators: name: Lertcharnrit, Thanik
Publisher: name: Washington State University
Year: 1984
Subjects: Archaeology

description: WSU Alumnus Thanik Lertcharnrit (center foreground) and other undergraduate colleagues at the Faculty of Archaeology, Silpakorn University, Bangkok, Thailand. The photo was taken in either 1984 or 1985. Note that most of the students at the time were women. Dr. Lertcharnrit later earned his MA and PhD degrees at Washington State University, with William Lipe as his advisor. Dr. Lertcharnrit is currently a Professor at Silpakorn and was interviewed in the Pioneers project which tracked historical data on leaders in Cultural Resource Management Archaeology with connections to WSU. For more information about the Pioneers project, led by WSU Professors Shannon Tushingham and William Lipe, see: https://labs.wsu.edu/tushingham-lab/wsu-pioneers-in-crm-project/. For more information about Dr. Lertcharnrit’s interview and Wikipedia research by WSU undergraduate student Alec Bowder, see: https://doi.org/10.7273/000000021
Associations between mothers' and daughters' physical activity behavior, motivation, and body image perceptions: A multi-method study.
Creators: name: Thom, Julie D.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Psychology, Behavioral.

description: The purpose of this thesis was to examine the associations among mothers' and daughters' physical activity behavior, motivation and body image perceptions using a multi-method approach. Phase 1 of this study was quantitative, and served to investigate the relationships between mothers' and daughters' physical activity behavior and motivation. Social Learning Theory (Bandura, 1977) and the Deviancy Model (Jessor & Jessor, 1977) were both used in order to investigate mother-daughter activity behaviors. For Phase 1, three groups were established based on the mothers' scores from the questionnaire: non-, moderate and high frequency exercisers. In order to further examine the mother-daughter relationship and specifically to investigate body image perceptions, a second qualitative phase (Phase 2) was conducted. Phase 2 consisted of interviewing 10 mothers and daughters (5 mother-daughter pairs). For this phase, a semi-structured interview guide was developed to further assess motivation and body image perceptions of both the mothers' and daughters'. Also, a Body Esteem Scale (Mendelson, White & Mendelson, 1997--98) was administered to the interviewees before conducting the interview. (Abstract shortened by UMI.)
Development of innovative anchorage system for CFRP ground anchors
Creators: name: Elias, Nabeel
Publisher: name: Swinburne
Year: 2024

description: Ground anchors are utilized throughout the construction industry in a temporary and permanent capacity for a myriad of structures. Steel is the prevalent material although the use of carbon fibre in this industry has been researched. Due to fibre’s high cost and the difficulty in gripping and stressing, adoption of the material has been stagnant. Gripping attachments and techniques in this research were developed in order to address the adoption issue. Two systems were researched and were shown to be successful, with one system being taken to a full scale test under the auspices of industry ground anchor installers.
Capacité des systèmes de télécommunication à antennes multiples dans les canaux à évanouissements lents de Rayleigh.
Creators: name: Gauthier, Éric.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Engineering, Electronics and Electrical.

description: Cette thèse porte sur la capacité des systèmes de télécommunication clans les canaux à évanouissements lents de Rayleigh. On s'intéresse plus particulièrement aux systèmes comportant plusieurs antennes à l'émetteur et au récepteur et à l'effet de cette diversité spatiale sur la capacité. La capacité de systèmes à antennes multiples est d'abord étudiée pour le cas où l'état du canal n'est connu qu'au récepteur. Ensuite, nous étudions le cas où l'émetteur connaît aussi l'état du canal, ce qui permet alors d'adapter les symboles transmis selon la réalisation du canal. Nous présentons alors un algorithme afin de déterminer le prétraitement à liémetteur qui maximise la capacité. Finalement, nous approfondissons le cas où l'émetteur connaît aussi l'état du canal en simulant des erreurs d'estimation du canal à l'émetteur, et nous présentons l'effet de ces estimations imparfaites sur la capacité.
title: Tea-induced improvement of endothelial function in humans
title: No role for epigallocatechin gallate (EGCG)
titleType: Subtitle
Creators: name: Lorenz, Mario
name: Rauhut, Franziska
name: Hofer, Christine
name: Gwosc, Stefanie
name: Mueller, Eda
name: Praeger, Damaris
name: Zimmermann, Benno F.
name: Wernecke, Klaus-Dieter
name: Baumann, Gert
name: Stangl, Karl
name: Stangl, Verena
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Cardiovascular biology
subject: Translational research
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Consumption of tea is inversely associated with cardiovascular diseases. However, the active compound(s) responsible for the protective effects of tea are unknown. Although many favorable cardiovascular effects in vitro are mediated by epigallocatechin gallate (EGCG), its contribution to the beneficial effects of tea in vivo remains unresolved. In a randomised crossover study, a single dose of 200 mg EGCG was applied in three different formulas (as green tea beverage, green tea extract (GTE), and isolated EGCG) to 50 healthy men. Flow-mediated dilation (FMD) and endothelial-independent nitro-mediated dilation (NMD) was measured before and two hours after ingestion. Plasma levels of tea compounds were determined after each intervention and correlated with FMD. FMD significantly improved after consumption of green tea containing 200 mg EGCG (p
INVESTIGATION OF DNA DAMAGE REPAIR IN ARCHAEA THROUGH THE DEVELOPMENT OF AN INDUCIBLE IN VIVO DOUBLE-STRAND BREAK REPAIR SYSTEM IN THE HYPERTHERMOPHILIC ACIDOPHILE SACCHAROLOBUS SOLFATARICUS
Creators: name: Jones, Brianne Jamison
Publisher: name: Washington State University
Year: 2026
Subjects: subject: Archaea
subject: double-strand break repair
subject: In vivo break repair
subject: Saccharolobus solfataricus
subject: DNA Repair
subject: Microbiology
subject: FOS: Biological sciences

description: DNA damage is a frequent occurrence in the genome and can take shape in many forms including abasic sites, lesions, and strand breaks. After damage, the repair of the DNA is imperative for maintaining proper cellular functions including replication and protein synthesis. A detrimental form of damage is double-strand breaks (DSBs) which involve breakage of both strands of DNA. The repair of DSBs can be executed through a variety of mechanisms, but repair via homologous recombination (HR) offers a product with minimal errors suitable for maintaining genomic integrity. In the first part of this work, we investigate the mechanism for repair of a DSB in one strain of the hyperthermophilic archaeon Saccharolobus solfataricus through the construction and employment of a novel in vivo inducible site-directed DSB repair assay. With this assay we can elucidate arrival, persistence, and localization of DNA repair proteins implicated in the repair of a DSB by HR. The second part of this work expands upon the first part in a temporal investigation of protein dynamics in the SsoRadA recombinase, two recombinase paralogs SsoRal1 and SsoRal3, as well as the HR accessory protein SsoSwi2/Snf2 in two strains of S. solfataricus. Through isolated and temporal investigations, we have determined a break side-preference in repair as well as variation in localization between these repair proteins and between two strains of S. solfataricus contributing to basic in vivo DSB repair biochemistry previously unknown in the highly understudied domain of life, Archaea. Additionally, this work aims to further understand the conservation of proteins in mechanisms across multiple domains of life.
Hepatitis B virus and HIV co-infection among pregnant women in Rwanda
Creators: name: Mutagoma, Mwumvaneza
name: Balisanga, Helene
name: Malamba, Samuel S
name: Sebuhoro, Dieudonné
name: Remera, Eric
name: Riedel, David J
name: Kanters, Steve
name: Nsanzimana, Sabin
Publisher: name: BioMed Central
Year: 2018

description: Background Hepatitis B virus (HBV) affects people worldwide but the local burden especially in pregnant women and their new born babies is unknown. In Rwanda HIV-infected individuals who are also infected with HBV are supposed to be initiated on ART immediately. HBV is easily transmitted from mother to child during delivery. We sought to estimate the prevalence of chronic HBV infection among pregnant women attending ante-natal clinic (ANC) in Rwanda and to determine factors associated with HBV and HIV co-infection. Methods This study used a cross-sectional survey, targeting pregnant women in sentinel sites. Pregnant women were tested for hepatitis B surface antigen (HBsAg) and HIV infection. A series of tests were done to ensure high sensitivity. Multivariable logistic regression was used to identify independent predictors of HBV-HIV co-infection among those collected during ANC sentinel surveillance, these included: age, marital status, education level, occupation, residence, pregnancy and syphilis infection. Results The prevalence of HBsAg among 13,121 pregnant women was 3.7% (95% CI: 3.4–4.0%) and was similar among different socio-demographic characteristics that were assessed. The proportion of HIV-infection among HBsAg-positive pregnant women was 4.1% [95% CI: 2.5–6.3%]. The prevalence of HBV-HIV co-infection was higher among women aged 15-24 years compared to those women aged 25–49 years [aOR = 6.9 (95% CI: 1.8–27.0)]. Women residing in urban areas seemed having HBV-HIV co-infection compared with women residing in rural areas [aOR = 4.3 (95% CI: 1.2–16.4)]. Women with more than two pregnancies were potentially having the co-infection compared to those with two or less (aOR = 6.9 (95% CI: 1.7–27.8). Women with RPR-positive test were seemed associated with HBV-HIV co-infection (aOR = 24.9 (95% CI: 5.0–122.9). Conclusion Chronic HBV infection is a public health problem among pregnant women in Rwanda. Understanding that HBV-HIV co-infection may be more prominent in younger women from urban residences will help inform and strengthen HBV prevention and treatment programmes among HIV-infected pregnant women, which is crucial to this population.
Traitement des dépôts de REL dans Zenodo : guide pour responsable des dépôts
Creators: name: fabriqueREL
Publisher: name: fabriqueREL
Year: 2024
Subjects: Ressources éducatives libres
Publications en libre accès
Guides et manuels

description: Ce guide présente la procédure de dépôts de REL dans Zenodo pour les REL disciplinaires créées lors des sollicitations de la fabriqueREL et pour les REL créées par l'équipe de la fabriqueREL (metaREL). En annexe, on y présente aussi le schéma de métadonnées recommandées.
description: Ressources éducatives libres

Open educational resources

REL

OER
description: Discipline : Autre

Format : Texte

Type de la ressource : Objet d'apprentissage

Type de matériel pédagogique : Guide
Synthetic studies directed towards the antineoplastic macrolide bryostatins.
Creators: name: Rey, Allan W.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Chemistry, Biochemistry.

description: This thesis describes stereocontrolled and practical routes to the C(1)-C(9), C(17)-C(20), and C(21)-C(27) synthons of bryostatins, which are a closely related family of 20-membered ring lactones embedding 1,3-polyol units. Bryostatins are isolated in minute quantities from the marine Bryozoan Bugula neritina and possess exceptional antineoplastic activity. Membrane-enclosed enantioselective enzymatic hydrolysis was successfully employed for the generation of gram quantities of the versatile building block (3R)-methoxymethoxypentadioic acid, monomethyl ester (51) (Chapter 2). This compound was used in the synthesis of the C(1)-C(5) segment of bryostatins. Preliminary synthetic studies towards the C(1)-C(9) subunit are described in Chapter 3. Wittig and dithiane approaches were unfortunately unsuccessful for the connection of an enzymatically derived 5 carbon unit with a D-pantolactone derived 4 carbon unit. Chapter 4 describes the practical synthesis of the C(1)-C(9) fragment of bryostatin in forms suitable for both structure/activity studies and synthetic elaboration. The pivotal step utilized a diastereoselective Mukaiyama aldol condensation of a diketene derived silylenol ether with an enzymatically derived chiral $\beta$-alkoxyaldehyde. Chapter 5 details the conversion of D-pantolactone and of D-galactono-1,4-lactone into the C(17)-C(20) and C(21)-C(27) synthons of bryostatins via a chiron approach. A study of nucleophilic additions onto chiral substituted $\gamma$-lactol templates is discussed in Chapter 6. This provided valuable information regarding the coupling of the C(17)-C(20) and C(21)-C(27) segments of bryostatins. As well, the results demonstrate the potential utility of $\gamma$-lactols as templates--a relatively unexplored area in asymmetric synthetic chemistry.
Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
Creators: name: Cerda-Esteban, Nuria
name: Naumann, Heike
name: Ruzittu, Silvia
name: Mah, Nancy
name: Pongrac, Igor M.
name: Cozzitorto, Corinna
name: Hommel, Angela
name: Andrade-Navarro, Miguel A.
name: Bonifacio, Ezio
name: Spagnoli, Francesca M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Organogenesis
subject: Reprogramming
subject: Transdifferentiation
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: The development of a successful lineage reprogramming strategy of liver to pancreas holds promises for the treatment and potential cure of diabetes. The liver is an ideal tissue source for generating pancreatic cells, because of its close developmental origin with the pancreas and its regenerative ability. Yet, the molecular bases of hepatic and pancreatic cellular plasticity are still poorly understood. Here, we report that the TALE homeoprotein TGIF2 acts as a developmental regulator of the pancreas versus liver fate decision and is sufficient to elicit liver-to-pancreas fate conversion both ex vivo and in vivo. Hepatocytes expressing Tgif2 undergo extensive transcriptional remodelling, which represses the original hepatic identity and, over time, induces a pancreatic progenitor-like phenotype. Consistently, in vivo forced expression of Tgif2 activates pancreatic progenitor genes in adult mouse hepatocytes. This study uncovers the reprogramming activity of TGIF2 and suggests a stepwise reprogramming paradigm, whereby a ‘lineage-restricted’ dedifferentiation step precedes the identity switch.