cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Table S1 from Patterns of predator neophobia: a meta-analytic review
Creators: name: Crane, Adam L.
name: Ferrari, Maud C. O.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Data on neophobia included in the meta-analysis, with their classifications and effect sizes (transformed Hedges’ g values) for: baseline neophobia vs. control (baseline score) and induced neophobia vs. baseline neophobia (induced score) sorted by taxonomic class with sample sizes in parentheses
(3163) Evelyn Mary Hargreaves
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Characterization of the lymphocyte membrane receptor for factor H ( 1H- globulin) with an antibody to anti-factor H idiotype
Creators: name: Lambris, J. D.
name: Ross, G. D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1982

description: Antibody to the binding site (idiotype) of anti-factor H was shown to have specificity for both B lymphocyte membrane H receptors and C3b. Goat F(ab')(2) anti-human H was purified by absorption and elution from H agarose and used for rabbit immunization to produce anti-anti-H (aaH). After absorption with nonimmune goat IgG, (125)I-labeled aaH bound to B lymphocytes and to sheep erythrocytes coated with C3b (EC3b) but did not bind to T lymphocytes or to EC3d. All B cell- and C3b-specific activities of the aaH were removed and subsequently recovered by absorption and elution of the antibody from either C3-agarose or goat-anti-H-agarose. This indicated that the aaH probably recognized a single common antigenic structure that was shared by anti-H, C3b, and the membranes of B cells. Affinity-purified aaH resembled H in that it bound to B cells, blocked the uptake of H onto B cell H receptors, and triggered B cells to release endogenous factor I (C3b inactivator). In addition, aaH functioned with factor I as either a cofactor for cleavage of fluid-phase C3b or a potentiator for cleavage of bound C3b. This same spectrum of C3 binding functions could not be demonstrated with either sheep anti-C3b or rabbit-anti-C3c. Analysis by sodium dodecyl sulfate- polyacrylamide get electrophoresis of the [(3)H]leucine intrinsically labeled B cell proteins reactive with the purified aaH revealed proteins of 100,000 M(r) and 50,000 M(r) without reduction, and after complete reduction of disulfide bonds, a single protein band of 50,000 M(r). This same protein molecular weight profile was also demonstrated with labeled B cell proteins that were absorbed and eluted from H-agarose. Thus, aaH is apparently specific for both B cell H receptors and C3b. However, because parallel analysis of C3b confirmed its known 115,000- and 75,000-M(r) polypeptide chain structure, the H receptor is probably not C3b and shares only the structure of the H binding site with C3b.
LA HERMANA SOMBRA (LAS SIETE HERMANAS 3) LUCINDA RILEY ePub gratis
Creators: name: Stagg
Publisher: name: Zenodo
Year: 2024

description: LA HERMANA SOMBRA (LAS SIETE HERMANAS 3) de LUCINDA RILEY

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LA HERMANA SOMBRA (LAS SIETE HERMANAS 3)

LUCINDA RILEY

Número de páginas: 592

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788401018350

Editorial: PLAZA & JANES EDITORES

Año de edición: 2017

 

 

 

 

 

Descarga de libros electrónicos en línea en pdf. LA HERMANA SOMBRA (LAS SIETE HERMANAS 3) DJVU CHM iBook 9788401018350

 

Overview

 

La hermana sombraes el tercer libro de la serie basada en la mitología griega y en la astrología, «Las siete hermanas», de la autora superventas mundial Lucinda Riley.

Siete hermanas, siete destinos, un padre con un pasado misterioso...

Star D'Aplièse se encuentra en una encrucijada tras la repentina muerte de su padre, el misterioso millonario Pa Salt. Ha dejado a cada una de sus seis hijas una pista sobre sus orígenes, pero Star, la más enigmática de todas, tiene serias dudas sobre la necesidad de aventurarse y perder la seguridad que la estrecha relación con su hermana CeCe le brinda. A la desesperada decide seguir la pista, que la conduce a una librería de antiguo en Londres y al comienzo de un nuevo mundo para ella.

Hace cien años Flora MacNichol jura que nunca se casará. Se siente feliz y segura en su casa en el Lake District cerca de Beatrix Potter, a quien idolatra. Pero se ve arrastrada contra su voluntad hasta Londres, a la casa de una de las personas más influyentes de la sociedad eduardiana: Alice Keppel, la amante más famosa de Eduardo VII, el hijo mayor de la reina Victoria.

Flora se debate entre el amor apasionado y la obligación hacia su familia al mismo tiempo que se siente como un pe...
Allen, I.C. et al. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J. Exp. Med. 207, 1045-1056
Creators: name: Uronis, Joshua M.
name: Ting, Jenny P.Y.
name: Rogers, Arlin B.
name: Holl, Eda K.
name: Woodford, Rita Marie T.
name: Allen, Irving C.
name: Herfarth, Hans H.
name: Jobin, Christian
name: Tekippe, Erin Mc Elvania
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Colitis-associated cancer (CAC) is a major complication of inflammatory bowel diseases. We show that components of the inflammasome are protective during acute and recurring colitis and CAC in the dextran sulfate sodium (DSS) and azoxymethane + DSS models. Mice lacking the inflammasome adaptor protein PYCARD (ASC) and caspase-1 demonstrate increased disease outcome, morbidity, histopathology, and polyp formation. The increased tumor burden is correlated with attenuated levels of IL-1beta and IL-18 at the tumor site. To decipher the nucleotide-binding domain, leucine-rich-repeat-containing (NLR) component that is involved in colitis and CAC, we assessed Nlrp3 and Nlrc4 deficient mice. Nlrp3(-/-) mice showed an increase in acute and recurring colitis and CAC, although the disease outcome was less severe in Nlrp3(-/-) mice than in Pycard(-/-) or Casp1(-/-) animals. No significant differences were observed in disease progression or outcome in Nlrc4(-/-) mice compared with similarly treated wild-type animals. Bone marrow reconstitution experiments show that Nlrp3 gene expression and function in hematopoietic cells, rather than intestinal epithelial cells or stromal cells, is responsible for protection against increased tumorigenesis. These data suggest that the inflammasome functions as an attenuator of colitis and CAC.
When Ramanujan meets time-frequency analysis in complicated time series analysis
Creators: name: Chen, Ziyu
name: Wu, Hau-Tieng
Publisher: name: arXiv
Year: 2020
Subjects: subject: Signal Processing (eess.SP)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Methodology (stat.ME)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: To handle time series with complicated oscillatory structure, we propose a novel time-frequency (TF) analysis tool that fuses the short time Fourier transform (STFT) and periodic transform (PT). Since many time series oscillate with time-varying frequency, amplitude and non-sinusoidal oscillatory pattern, a direct application of PT or STFT might not be suitable. However, we show that by combining them in a proper way, we obtain a powerful TF analysis tool. We first combine the Ramanujan sums and $l_1$ penalization to implement the PT. We call the algorithm Ramanujan PT (RPT). The RPT is of its own interest for other applications, like analyzing short signal composed of components with integer periods, but that is not the focus of this paper. Second, the RPT is applied to modify the STFT and generate a novel TF representation of the complicated time series that faithfully reflect the instantaneous frequency information of each oscillatory components. We coin the proposed TF analysis the Ramanujan de-shape (RDS) and vectorized RDS (vRDS). In addition to showing some preliminary analysis results on complicated biomedical signals, we provide theoretical analysis about RPT. Specifically, we show that the RPT is robust to three commonly encountered noises, including envelop fluctuation, jitter and additive noise.
Environment, morphology and stellar populations of bulgeless low surface brightness galaxies
Creators: name: Shao, X.
name: Disseau, K.
name: Yang, Y. B.
name: Hammer, F.
name: Puech, M.
name: Rodrigues, M.
name: Liang, Y. C.
name: Deng, L. C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Based on the Sloan Digital Sky Survey DR 7, we investigate the environment, morphology and stellar population of bulgeless low surface brightness (LSB) galaxies in a volume-limited sample with redshift ranging from 0.024 to 0.04 and $M_r$ $\leq$ $-18.8$. The local density parameter $Σ_5$ is used to trace their environments. We find that, for bulgeless galaxies, the surface brightness does not depend on the environment. The stellar populations are compared for bulgeless LSB galaxies in different environments and for bulgeless LSB galaxies with different morphologies. The stellar populations of LSB galaxies in low density regions are similar to those of LSB galaxies in high density regions. Irregular LSB galaxies have more young stars and are more metal-poor than regular LSB galaxies. These results suggest that the evolution of LSB galaxies may be driven by their dynamics including mergers rather than by their large scale environment.
description: 12 pages, 13 figures, Accepted by A&A
Local hidden variable values without optimization procedures
Creators: name: Goyeneche, Dardo
name: Bruzda, Wojciech
name: Turek, Ondřej
name: Alsina, Daniel
name: Życzkowski, Karol
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The problem of computing the local hidden variable (LHV) value of a Bell inequality plays a central role in the study of quantum nonlocality. In particular, this problem is the first step towards characterizing the LHV polytope of a given scenario. In this work, we establish a relation between the LHV value of bipartite Bell inequalities and the mathematical notion of excess of a matrix. Inspired by the well developed theory of excess, we derive several results that directly impact the field of quantum nonlocality. We show infinite families of bipartite Bell inequalities for which the LHV value can be computed exactly, without needing to solve any optimization problem, for any number of measurement settings. We also find tight Bell inequalities for a large number of measurement settings.
description: 14 pages. Comments are very welcome! Accepted in Quantum (January 9, 2023)
Table S2 from Patterns of predator neophobia: a meta-analytic review.
Creators: name: Crane, Adam L.
name: Ferrari, Maud C. O.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Estimated marginal means for test cue type × taxonomic class.
Reply to Garcia et al.: Common mistakes in measuring frequency dependent word characteristics
Creators: name: Dodds, P. S.
name: Clark, E. M.
name: Desu, S.
name: Frank, M. R.
name: Reagan, A. J.
name: Williams, J. R.
name: Mitchell, L.
name: Harris, K. D.
name: Kloumann, I. M.
name: Bagrow, J. P.
name: Megerdoomian, K.
name: McMahon, M. T.
name: Tivnan, B. F.
name: Danforth, C. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Computation and Language (cs.CL)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We demonstrate that the concerns expressed by Garcia et al. are misplaced, due to (1) a misreading of our findings in [1]; (2) a widespread failure to examine and present words in support of asserted summary quantities based on word usage frequencies; and (3) a range of misconceptions about word usage frequency, word rank, and expert-constructed word lists. In particular, we show that the English component of our study compares well statistically with two related surveys, that no survey design influence is apparent, and that estimates of measurement error do not explain the positivity biases reported in our work and that of others. We further demonstrate that for the frequency dependence of positivity---of which we explored the nuances in great detail in [1]---Garcia et al. did not perform a reanalysis of our data---they instead carried out an analysis of a different, statistically improper data set and introduced a nonlinearity before performing linear regression.
description: 5 pages, 2 figures, 1 table. Expanded version of reply appearing in PNAS 2015
[Pdf/ePub/Mobi] JUEGO LIMPIO - TOVE JANSSON descargar ebook gratis
Creators: name: Welch
Publisher: name: Zenodo
Year: 2024

description: JUEGO LIMPIO de TOVE JANSSON

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Ficha técnica

JUEGO LIMPIO

TOVE JANSSON

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788412662047

Editorial: MINUSCULA

Año de edición: 2024

 

 

 

 

 

Descarga gratuita de libros de ordenador en línea. JUEGO LIMPIO FB2 iBook 9788412662047 de TOVE JANSSON

 

Overview

"Vivían cada una en un extremo de un gran bloque de pisos cerca del puerto, y entre sus estudios se encontraba el desván, una tierra de nadie impersonal de pasillos altos con puertas de tablones a ambos lados. A Mari le gustaba cruzar el desván, marcaba un inciso de neutralidad necesaria entre los dominios de las dos. Podía pararse por el camino a oír la lluvia sobre el tejado de latón, contemplar la ciudad, que ya encendía sus luces, o detenerse solo para disfrutar del sosiego. Nunca se preguntaban: ¿Has podido trabajar hoy? Tal vez veinte o treinta años atrás sí, pero con el tiempo aprendieron. Hay vacíos que es necesario respetar; esos períodos a menudo muy largos en los que no vemos la imagen, no encontramos las palabras, y es preciso que nos dejen en paz." Mari y Jonna, dos artistas que viven juntas desde hace decadas respetando al máximo el espacio personal de cada una, se citan para ver una película que dan por televisión, o van de viaje por Europa y Estados Unidos, o pasan temporadas en una cabaña situada en una isla solitaria en la que pescan con red, se sientan a admirar las tormentas y pasean entre las rocas con la complicidad de una vida compartida. "Juego limpio es una novela" —o un conjunto de relatos, según se mire— de trasfondo autobiográfico e
(3157) Richard Taylor
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Figure S1 from Patterns of predator neophobia: a meta-analytic review.
Creators: name: Crane, Adam L.
name: Ferrari, Maud C. O.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: (A) The ‘free exploratory paradigm’ consisting of an arena (typically 30×20×20 cm) subdivided into six equal compartments with small interconnecting doors. The removal of a dividing barrier (depicted by the centre gray line) allows test subjects to move among familiar compartments with bedding vs. empty novel compartments [image adapted from Matos et al. [1]]. (B) The ‘elevated plus maze’ consists of four arms, two of which are enclosed by walls (typically 30 cm high) vs. two that lack walls. The base of the maze is elevated above the floor (typically by 50 cm) [image adapted from Walf and Frye [2]].
PreCNet: Next-Frame Video Prediction Based on Predictive Coding
Creators: name: Straka, Zdenek
name: Svoboda, Tomas
name: Hoffmann, Matej
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: Predictive coding, currently a highly influential theory in neuroscience, has not been widely adopted in machine learning yet. In this work, we transform the seminal model of Rao and Ballard (1999) into a modern deep learning framework while remaining maximally faithful to the original schema. The resulting network we propose (PreCNet) is tested on a widely used next frame video prediction benchmark, which consists of images from an urban environment recorded from a car-mounted camera, and achieves state-of-the-art performance. Performance on all measures (MSE, PSNR, SSIM) was further improved when a larger training set (2M images from BDD100k), pointing to the limitations of the KITTI training set. This work demonstrates that an architecture carefully based in a neuroscience model, without being explicitly tailored to the task at hand, can exhibit exceptional performance.
description: Accepted by IEEE Transactions on Neural Networks and Learning Systems (TNNLS)
Polyanalytic Hardy decomposition of higher order Lipschitz functions
Creators: name: Blaya, Ricardo Abreu
name: Toranzo, Lianet De la Cruz
Publisher: name: arXiv
Year: 2020
Subjects: subject: Complex Variables (math.CV)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics

description: This paper is concerned with the problem of decomposing a higher order Lipschitz function on a closed Jordan curve $Γ$ into a sum of two polyanalytic functions in each open domain defined by $Γ$. Our basic tools are the Hardy projections related to a singular integral operator arising in polyanalytic function theory, which, as it is proved here, represents an involution operator on the higher order Lipschitz classes. Our result generalizes the classical Hardy decomposition of Holder continuous functions on the boundary of a domain.
Supplemental material from Modulation of social space by dopamine in Drosophila melanogaster, but no effect on the avoidance of the Drosophila stress odorant.
Creators: name: Fernandez, Robert W.
name: Adesanya A. Akinleye
name: Nurilov, Marat
name: Feliciano, Omar
name: Lollar, Matthew
name: Aijuri, Rami R.
name: O'Donnell, Janis M.
name: Simon, Anne F.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Neuroscience
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Supplemental results, detailed material and methods, supplemental table, supplemental figures.
On the boundary properties of Bernstein estimators on the simplex
Creators: name: Ouimet, Frédéric
Publisher: name: arXiv
Year: 2020
Subjects: subject: Statistics Theory (math.ST)
subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 62G05, 60F99, 62G07, 62G20

description: In this paper, we study the asymptotic properties (bias, variance, mean squared error) of Bernstein estimators for cumulative distribution functions and density functions near and on the boundary of the $d$-dimensional simplex. Our results generalize those found by Leblanc (2012), who treated the case $d=1$, and complement the results from Ouimet (2021) in the interior of the simplex. Since the "edges" of the $d$-dimensional simplex have dimensions going from $0$ (vertices) up to $d - 1$ (facets) and our kernel function is multinomial, the asymptotic expressions for the bias, variance and mean squared error are not straightforward extensions of one-dimensional asymptotics as they would be for product-type estimators studied by almost all past authors in the context of Bernstein estimators or asymmetric kernel estimators. This point makes the mathematical analysis much more interesting.
description: 16 pages, 0 figures
DOWNLOAD [PDF] {EPUB} Womanhood: The Bare Reality by Laura Dodsworth
Creators: name: Norton
Publisher: name: Zenodo
Year: 2024

description: Womanhood: The Bare Reality by Laura Dodsworth

 

 

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Womanhood: The Bare Reality

Laura Dodsworth

Page: 336

Format: pdf, ePub, mobi, fb2

ISBN: 9781780664651

Publisher: Pinter & Martin Ltd

 

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Womanhood: The Bare Reality eBook: Laura Dodsworth - Amazon.ca 100 women bare all in an empowering collection of photographs and interviews about Womanhood. Vagina, vulva, lady garden, pussy, beaver, c**t, fanny… Manhood: The Bare Reality (9781780664255): Laura - Amazon.com Laura Dodsworth's Kickstarter campaign to finance Bare Reality: 100 women, Their breasts, Their stories achieved its funding target within one day and the  BARE REALITY: 100 women and their breasts by Laura - Kickstarter Laura Dodsworth is raising funds for BARE REALITY: 100 women and their breasts on Kickstarter! 100 women bare their breasts alongside  Bare Reality: 100 Women, Their Breasts, Their Stories - Amazon.com Editorial Reviews. Review. This touching, inspirational book cuts through the sexual Buy Bare Reality: 100 Women, Their Breasts, Their Stories: Read 16 Books Reviews - Amazon.com. 'Womanhood: The Bare Reality' 100 women bare all in an 'Womanhood: The Bare Reality' 100 women bare all in an empowering collection of photographs and interviews about Womanhood. Photographing and Manhood: The Bare Reality (English Edition) eBook: Laura Just as Bare Reality: 100 women, their breasts, their stories presented the un- airbrushed truth about breasts for women, Manhood: The Bare Reality shows us   Artist Laura Dodsworth breaks taboos by photographing 100 vaginas Photographer and author Laura Dodsworth has just released a new book in her Bare Reality series called Womanhood. On her website, Bare
Stephan Packard - Transnational Imagination and the Ideology of Fiction: Picturing Cultural Others in Intercultural Comic Publications
Creators: name: Packard, Stephan
Publisher: name: University of the Arts London
Year: 2020
Subjects: subject: 199999 Studies in the Creative Arts and Writing not elsewhere classified
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: 02/07/2020 15:00 Room 1 #traprn
Mainstream comics strive towards images of transnationality in various ways: by addressing international markets and audiences, by including transnationally diverse creators, and by depicting transnational settings and dramatis personae on their pages. As the latter are typically fictional, this practice usually includes the necessary invention of the transnational other – a freedom of imagination that might, however, similarly apply to the projected images of producers and audiences. As contradictions between different conceptions and material practices of transnationality arise, an ideological element of fiction may be traced that is situated beyond the naïve questions of confusing the fictional and the real, and that instead operates by confounding the social imaginary with possibilities of political agency. The talk will trace some examples of these contradictions through their aesthetic and stylistic consequences on the page and back to a reflection of the imagined transnational comic book marketplace.
[Pdf/ePub/Mobi] CUANDO NO QUEDEN MÁS ESTRELLAS QUE CONTAR - MARIA MARTINEZ descargar ebook gratis
Creators: name: Jimenez
Publisher: name: Zenodo
Year: 2024

description: CUANDO NO QUEDEN MÁS ESTRELLAS QUE CONTAR de MARIA MARTINEZ

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CUANDO NO QUEDEN MÁS ESTRELLAS QUE CONTAR

MARIA MARTINEZ

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788408247241

Editorial: PLANETA

 

 

 

 

 

Libros electrónicos gratis para descargar para la tableta de Android CUANDO NO QUEDEN MÁS ESTRELLAS QUE CONTAR (Literatura española) 9788408247241 DJVU

 

Overview

¿Cómo se ignora lo que late en tu interior? ¿Cómo se recupera el rumbo de una vida trazada por una mentira?    Desde muy pequeña, Maya se ha sacrificado en cuerpo y alma por el ballet. Trabaja como solista en la Compañía Nacional de Danza y los ballets más prestigiosos han puesto sus ojos en ella. Sin embargo, un grave accidente acaba con su futuro prometedor. El único mundo que Maya conoce se ha derrumbado. Su abuela, que ha guiado cada uno de sus pasos, la culpa por lo sucedido. La ausencia de su madre pesa más que nunca. Y un hallazgo fortuito abrirá una profunda herida.   Un viaje inesperado, una chica incompleta y una verdad escondida en una caja de música. A veces, dejar que suceda es todo lo que necesitas.
(3159) Janet McCorquodale
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Enterocyte-Derived TAK1 Signaling Prevents Epithelium Apoptosis and the Development of Ileitis and Colitis
Creators: name: Akira, Shizuo
name: Robine, Sylvie
name: Inagaki, Maiko
name: Kajino-Sakamoto, Rie
name: Jobin, Christian
name: Lippert, Elisabeth
name: Ninomiya-Tsuji, Jun
name: Matsumoto, Kunihiro
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Recent studies have revealed that TAK1 kinase is an essential intermediate in several innate immune signaling pathways. In this study, we investigated the role of TAK1 signaling in maintaining intestinal homeostasis by generating enterocytes-specific constitutive and inducible gene deleted TAK1 mice. We found that enterocyte-specific constitutive TAK1 deleted mice spontaneously developed intestinal inflammation as observed by histological analysis and enhanced expression of IL-1β, MIP2 and IL-6 around the time of birth, which was accompanied by significant enterocytes apoptosis. When TAK1 was deleted in the intestinal epithelium of 4-week-old mice using an inducible knockout system, enterocytes underwent apoptosis and intestinal inflammation developed within 2–3 days following the initiation of gene deletion. We found that enterocytes apoptosis and intestinal inflammation were strongly attenuated when enterocyte-specific constitutive TAK1 deleted mice were crossed to TNF receptor 1 (TNFR1)−/− mice. However, these mice later (>14 days) developed ileitis and colitis. Thus, TAK1 signaling in enterocytes is essential for preventing TNF-dependent epithelium apoptosis and the TNF-independent development of ileitis and colitis. We propose that aberration in TAK1 signaling might disrupt intestinal homeostasis and favor the development of inflammatory disease.
Programmable skyrmion logic gates based on skyrmion tunneling
Creators: name: Sisodia, Naveen
name: Pelloux-Prayer, Johan
name: Buda-Prejbeanu, Liliana D.
name: Anghel, Lorena
name: Gaudin, Gilles
name: Boulle, Olivier
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Magnetic skyrmions are promising candidates as elementary nanoscale bits in logic-in-memory devices, intrinsically merging high density memory and computing capabilities. Here we exploit the dynamics of skyrmions interacting with anisotropy energy barriers patterned by ion irradiation to design programmable logic gates. Using micromagnetic simulations with experimental parameters, we show that a fine tuning of the barrier height and width allows the selective tunneling of skyrmions between parallel nanotracks triggered by skyrmion-skyrmion interaction. This can be leveraged to design skyrmion De-multiplexer (DMux) logic gate which works solely using skyrmions as logic inputs. By cascading and connecting demultiplexer gates with a specific topology, we develop a fully programmable logic gate capable of producing any possible logic output as a sum of all minterms generated by a given set of inputs without requiring any complex additional electric/magnetic interconversion. The proposed design is fully conservative and cascadable and paves a new pathway for full skyrmionic-based logic-in-memory devices.
Robust and programmable logic-in-memory devices exploiting skyrmion confinement and channeling using local energy barriers
Creators: name: Sisodia, Naveen
name: Pelloux-Prayer, Johan
name: Buda-Prejbeanu, Liliana D.
name: Anghel, Lorena
name: Gaudin, Gilles
name: Boulle, Olivier
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Magnetic skyrmions are promising candidates for logic-in-memory applications, intrinsically merging high density non-volatile data storage with computing capabilities, owing to their nanoscale size, fast motion, and mutual repulsions. However, concepts proposed so far suffer from reliability issues as well as inefficient conversion of magnetic information to electrical signals. In this paper, we propose a logic-in-memory device which exploits skyrmion confinement and channeling using anisotropy energy barriers to achieve reliable data storage and synchronous shift in racetracks combined with cascadable and reprogrammable logics relying purely on magnetic interactions. The device combines a racetrack shift register based on skyrmions confined in nanodots with Full Adder (FA) gates. The designed FA is reprogrammable and cascadable and can also be used to perform simple logic operations such as AND, OR, NOT, NAND, XOR and NXOR. The monolithic design of the logic gate and the absence of any complex electrical contacts makes the device ideal for integration with conventional CMOS circuitry.
Supplemental material from Modulation of social space by dopamine in Drosophila melanogaster, but no effect on the avoidance of the Drosophila stress odorant
Creators: name: Fernandez, Robert W.
name: Adesanya A. Akinleye
name: Nurilov, Marat
name: Feliciano, Omar
name: Lollar, Matthew
name: Aijuri, Rami R.
name: O'Donnell, Janis M.
name: Simon, Anne F.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Neuroscience
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Supplemental results, detailed material and methods, supplemental table, supplemental figure legends.
The p75 Neurotrophin Receptor Promotes Amyloid- (1-42)-Induced Neuritic Dystrophy In Vitro and In Vivo
Creators: name: Vander Griend, Lilith
name: Nguyen, Thuy Vi V.
name: Massa, Stephen M.
name: Wyss-Coray, Tony
name: Ishikawa, Chihiro
name: LeMieux, Melburne C.
name: Yang, Tao
name: Knowles, Juliet K.
name: Rajadas, Jayakumar
name: Longo, Frank M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Oligomeric forms of amyloid-beta (Abeta) are thought to play a causal role in Alzheimer's disease (AD), and the p75 neurotrophin receptor (p75(NTR)) has been implicated in Abeta-induced neurodegeneration. To further define the functions of p75(NTR) in AD, we examined the interaction of oligomeric Abeta(1-42) with p75(NTR), and the effects of that interaction on neurite integrity in neuron cultures and in a chronic AD mouse model. Atomic force microscopy was used to ascertain the aggregated state of Abeta, and fluorescence resonance energy transfer analysis revealed that Abeta oligomers interact with the extracellular domain of p75(NTR). In vitro studies of Abeta-induced death in neuron cultures isolated from wild-type and p75(NTR-/-) mice, in which the p75(NTR) extracellular domain is deleted, showed reduced sensitivity of mutant cells to Abeta-induced cell death. Interestingly, Abeta-induced neuritic dystrophy and activation of c-Jun, a known mediator of Abeta-induced deleterious signaling, were completely prevented in p75(NTR-/-) neuron cultures. Thy1-hAPP(Lond/Swe) x p75(NTR-/-) mice exhibited significantly diminished hippocampal neuritic dystrophy and complete reversal of basal forebrain cholinergic neurite degeneration relative to those expressing wild-type p75(NTR). Abeta levels were not affected, suggesting that removal of p75(NTR) extracellular domain reduced the ability of excess Abeta to promote neuritic degeneration. These findings indicate that although p75(NTR) likely does not mediate all Abeta effects, it does play a significant role in enabling Abeta-induced neurodegeneration in vitro and in vivo, establishing p75(NTR) as an important therapeutic target for AD.
Families of orthogonal Laurent polynomials, hyperelliptic Lie algebras and elliptic integrals
Creators: name: Cox, Ben
name: Im, Mee Seong
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mathematical Physics (math-ph)
subject: Representation Theory (math.RT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We describe a family of polynomials discovered via a particular recursion relation, which have connections to Chebyshev polynomials of the first and the second kind, and the polynomial version of Pell's equation. Many of their properties are listed in Section 3. We show that these families of polynomials in the variable $t$ satisfy certain second order linear differential equations that may be of interest to mathematicians in conformal field theory and number theory. We also prove that these families of polynomials in the setting of Date-Jimbo-Kashiwara-Miwa algebras when multiplied by a suitable power of $t$ are orthogonal with respect to explicitly-described kernels. Particular cases lead to new identities of elliptic integrals (see Section 5).
description: 22 pages
Quantum (Matrix) Geometry and Quasi-Coherent States
Creators: name: Steinacker, Harold C.
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: A general framework is described which associates geometrical structures to any set of $D$ finite-dimensional hermitian matrices $X^a, \ a=1,...,D$. This framework generalizes and systematizes the well-known examples of fuzzy spaces, and allows to extract the underlying classical space without requiring the limit of large matrices or representation theory. The approach is based on the previously introduced concept of quasi-coherent states. In particular, a concept of quantum Kähler geometry arises naturally, which includes the well-known quantized coadjoint orbits such as the fuzzy sphere $S^2_N$ and fuzzy $\mathbb{C} P^n_N$. A quantization map for quantum Kähler geometries is established. Some examples of quantum geometries which are not Kähler are identified, including the minimal fuzzy torus.
description: 35 pages. V2: minor corrections. V3: minor improvements
[download pdf] The Ghost Orchid: An Alex Delaware Novel by Jonathan Kellerman
Creators: name: Dennison
Publisher: name: Zenodo
Year: 2024

description: The Ghost Orchid: An Alex Delaware Novel by Jonathan Kellerman

 

 

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The Ghost Orchid: An Alex Delaware Novel

Jonathan Kellerman

Page: 416

Format: pdf, ePub, mobi, fb2

ISBN: 9780593861806

Publisher: Diversified Publishing

 

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Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact
Creators: name: Pinckney, Lennisha
name: Zylka, Mark J.
name: Paul, Ketema N.
name: Jones, Kelly A.
name: Gray, Cloe L.
name: Ehlen, J. Christopher
name: Philpot, Benjamin D.
name: Brager, Allison J.
name: DeBruyne, Jason P.
name: Burette, Susan
name: Weinberg, Richard J.
name: Evans, Jennifer A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Individuals with Angelman syndrome (AS) suffer sleep disturbances that severely impair quality of life. Whether these disturbances arise from sleep or circadian clock dysfunction is currently unknown. Here, we explored the mechanistic basis for these sleep disorders in a mouse model of Angelman syndrome (Ube3am−/p+ mice). Genetic deletion of the maternal Ube3a allele practically eliminates UBE3A protein from the brain of Ube3am−/p+ mice, because the paternal allele is epigenetically silenced in most neurons. However, we found that UBE3A protein was present in many neurons of the suprachiasmatic nucleus—the site of the mammalian circadian clock—indicating that Ube3a can be expressed from both parental alleles in this brain region in adult mice. We found that while Ube3am−/p+ mice maintained relatively normal circadian rhythms of behavior and light-resetting, these mice exhibited consolidated locomotor activity and skipped the timed rest period (siesta) present in wild-type (Ube3am+/p+) mice. Electroencephalographic analysis revealed that alterations in sleep regulation were responsible for these overt changes in activity. Specifically, Ube3am−/p+ mice have a markedly reduced capacity to accumulate sleep pressure, both during their active period and in response to forced sleep deprivation. Thus, our data indicate that the siesta is governed by sleep pressure, and that Ube3a is an important regulator of sleep homeostasis. These preclinical findings suggest that therapeutic interventions that target mechanisms of sleep homeostasis may improve sleep quality in individuals with AS.
Descargar PDF UNA SOLEDAD DEMASIADO RUIDOSA
Creators: name: Yoder
Publisher: name: Zenodo
Year: 2024

description: UNA SOLEDAD DEMASIADO RUIDOSA de BOHUMIL HRABAL

Descargar eBook gratis ➡ Link

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UNA SOLEDAD DEMASIADO RUIDOSA

BOHUMIL HRABAL

Número de páginas: 112

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788416252442

Editorial: GALAXIA GUTENBERG

Año de edición: 2015

 

 

 

 

 

Descargando audiolibros para encender UNA SOLEDAD DEMASIADO RUIDOSA 9788416252442 en español de BOHUMIL HRABAL

 

Overview

Desde hace treinta y cinco años, Hanta trabaja en una trituradora de papel destruyendo libros y reproducciones de cuadros. En cada una de las balas de papel que prepara conviven libros, litografías, ratoncillos aprisionados y su propio esfuerzo. Pero para él, esos libros son mucho más que papel para prensar: son toneladas de saber que la humanidad ha ido acumulando a lo largo de los siglos y que Hanta ha ido adquiriendo con su trabajo. Mientras deambula por Praga, repasa su vida a la vez que reflexiona sobre las enseñanzas de los grandes maestros: Lao Tse, Nietzsche, Hegel o Kant. Con la maravillosa prosa que le caracteriza, Bohumil Hrabal construye en Una soledad demasiado ruidosa, escrito cuando su obra estaba prohibida por el régimen comunista, una fábula sobre el sentido de la creación artística y literaria, sobre el amor y la soledad, la creación y la destrucción o la crueldad del tiempo que también alcana a Hanta, al que unos jóvenes obreros, gente modélica con nuevos métodos de trabajo, acaban sustituyendo. Esta es pues la historia de un hombre dejado al margen de la sociedad que contempla con entrañable lucidez su vida y encarna a todos aquellos que desafian al tiempo que les ha tocado vivir. Uno de los textos esenciales de su autor que llegó a afirmar que sólo había vivido para escribir este libro.

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Methods and Statistics from Social disappointment explains chimpanzees' behaviour in the inequity aversion task.
Creators: name: Engelmann, Jan M.
name: Clift, Jeremy B.
name: Herrmann, Esther
name: Tomasello, Michael
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour

description: Chimpanzees’ refusal of less-preferred food when an experimenter has previously provided preferred food to a conspecific has been taken as evidence for a sense of fairness. Here, we present a novel hypothesis—the social disappointment hypothesis—according to which food refusals express chimpanzees' disappointment in the human experimenter for not rewarding them as well as they could have. We tested this hypothesis using a two-by-two design in which food was either distributed by an experimenter or a machine and with a partner present or absent. We found that chimpanzees were more likely to reject food when it was distributed by an experimenter rather than by a machine and that they were not more likely to do so when a partner was present. These results suggest that chimpanzees’ refusal of less-preferred food stems from social disappointment in the experimenter and not from a sense of fairness.
Methods and Statistics from Social disappointment explains chimpanzees' behaviour in the inequity aversion task
Creators: name: Engelmann, Jan M.
name: Clift, Jeremy B.
name: Herrmann, Esther
name: Tomasello, Michael
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour

description: Chimpanzees’ refusal of less-preferred food when an experimenter has previously provided preferred food to a conspecific has been taken as evidence for a sense of fairness. Here, we present a novel hypothesis—the social disappointment hypothesis—according to which food refusals express chimpanzees' disappointment in the human experimenter for not rewarding them as well as they could have. We tested this hypothesis using a two-by-two design in which food was either distributed by an experimenter or a machine and with a partner present or absent. We found that chimpanzees were more likely to reject food when it was distributed by an experimenter rather than by a machine and that they were not more likely to do so when a partner was present. These results suggest that chimpanzees’ refusal of less-preferred food stems from social disappointment in the experimenter and not from a sense of fairness.
Dietary Choline Reverses Some, but Not All, Effects of Folate Deficiency on Neurogenesis and Apoptosis in Fetal Mouse Brain
Creators: name: Johnson, Amy R.
name: Zeisel, Steven H.
name: Craciunescu, Corneliu N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: In mice, maternal dietary folate, a cofactor in 1-carbon metabolism, modulates neurogenesis and apoptosis in the fetal brain. Similarly, maternal dietary choline, an important methyl-donor, also influences these processes. Choline and folate are metabolically interrelated, and we determined whether choline supplementation could reverse the effects of folate deficiency on brain development. Timed-pregnant mice were fed control (CT), folate-deficient (FD), or folate-deficient, choline-supplemented (FDCS) AIN-76 diets from d 11 to 17 (E11–17) of pregnancy, and on E17, fetal brains were collected for analysis. Compared with the CT group, the FD group had fewer neural progenitor cells undergoing mitosis in the ventricular zones of the developing mouse brain septum (47%; P < 0.01), hippocampus (29%; P < 0.01), striatum (34%; P < 0.01), and anterior and mid-posterior neocortex (33% in both areas; P < 0.01). In addition, compared with CT, the FD diet almost doubled the rate of apoptosis in the fetal septum and hippocampus (P < 0.01). In the FDCS group, the mitosis rates generally were intermediate between those of the CT and FD groups; mitosis rates in the septum and striatum were significantly greater compared with the FD group and were significantly lower than in the CT group only in the septum and neocortex. In the FDCS group, the hippocampal apoptosis rate was significantly lower than in the FD group (P < 0.01) and was the same as in the CT group. In the septum, the apotosis rate in the FDCS group was intermediate between the CT and FD groups' rates. These results suggest that neural progenitor cells in fetal forebrain are sensitive to maternal dietary folate during late gestation and that choline supplementation can modify some, but not all, of these effects.