cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
GIANT HOFFMANN-ZURHELLE'S NEVUS LIPOMATOSUS SUPERFICIALIS AT AN ATYPICAL SITE- CASE REPORT OF A RARE HAMARTOMA
Creators: name: Anannya S
name: Abyramy Balasundaram
name: Vivekanandh K
name: Vimal Chander R
name: Durgadevi G
name: Afthab Jameela Wahab
Publisher: name: Zenodo
Year: 2024

description: Abstract

Nevus lipomatosus cutaneous superficialis (NLCS) is an uncommon idiopathic benign cutaneous hamartoma, with the occurrence of ectopic mature adipose tissue in the dermis that does not extend into the subcutaneous adipose tissue. Clinically, there are two forms. The more prevalent classical presentation manifests as numerous yellow papules and nodules that are soft, pedunculated, non-tender, and frequently coalesce to create a plaque. The less common solitary form manifests as a sessile or dome-shaped papule appearing in the 3rd or 6th decade of life. The classical NLCS usually shows up within the first three decades of life or at birth. Although the pelvic or gluteal region is usually affected in this classic type, it can also sporadically affect the chest, face and abdomen with some authors reporting it on the scrotum, vulva and pinna. On very rare occasions the lesions can be giant. In this case report, we describe a giant classical NLCS in the neck region in a 53-year-old male undiagnosed since 40 years.
HTS-Technology for hybrid electric aircraft
Creators: name: Filipenko, Mykhaylo
Publisher: name: Karlsruhe
Year: 2017

description: The world of transportation is in a transition: From combustion engines to electric machines. This change is getting more and more momentum on the land, on the sea and in recent years also in the air. On the one hand, electric aircraft is supposed to open absolutely new opportunities for urban mobility with such concepts as prosed and currently heaviliy investigated by Uber, Vahana, CityAirbus or Lilium. On the other hand electric aircraft and in particular hybrid electric aircraft will allow to reduce the COx, NOx and noise emissions as required by the ACARE 2050 goals. Although demonstrated by several proof-of-concepts maiden flights by Siemens in close collaboration with Diamond Aircraft, Magnus and EXTRA that hybrid electric flight is possible, there are many technical challenges on the road to the entry into service of hybrid electric regional jet. Siemens and Airbus have a started collaboration in June 2016 to adress jointly this challanges and make a large step towards this ambitious goal. The challenges relate mainly to the weight and efficiency of electric propulsion components. Motors and generators at the multi-MW scale have been available for industrial applications for a large time - however at such weights that render flying with them impossible. With a power-to-weight ratio of around 0.5 kW/kg traction drives for motors or ships are significantly heavier than gas turbines which have a typical power-to-weight ratio of about 5 kW/kg to 9 kW/kg. With the SP260D Siemens Aircraft developed a electric propulsion direct drive motor with power of 260 kW and a weight of roughly 50 kg, therefore a power-to-weight ratio of about 5.2 kW/kg which is the currently world record. For doing so we went to the edge of magnetic, mechanical, thermal and electric properties of materials and involved numerical optimization to be as lightweight as possible. Nonetheless we need to take an additional big step. How to go even further with lightweight electric machines? An immense opportunity could offer high tempereratur superconductors as they allow far higher airgap magnetic fields than the best NeFeB magnets and much higher current densities in the stator. In this talk I would like to adress in how far superconductivity could allow to significatly increase the power-to-weight ratio of hybrid electric propulsion systems and therefore be a key technology for hybrid electric aircraft.
Milk Fever (Parturient Paresis) and Its Impact on Dairy Cattle Production
Creators: name: Dr. J. Shashank1*, Dr. M. Fibi Rani2
Publisher: name: veterinary today
Year: 2024

description: Milk fever (Parturient paresis) is a metabolic disturbance or production disease of dairy cattle that occurs just before or soon after calving due to low ionized calcium (Ca++) levels in the blood. It is associated with calcium drain within the fetus and milk during pregnancy and calving, respectively. It can be clinical or sub-clinical based on clinical signs. High yielding dairy cows are the most susceptible to milk fever during the peri-parturient period. Milk yield, parity, age, breed, body condition score (BCS), and diet composition of the animal are the most common factors that contribute to the occurrence, incidence and severity of milk fever. Economically, it reduces milk yield and fertility which leads to the culling of high producing dairy animals from a herd. Diagnosis of milk fever is based on history taking, clinical examination and laboratory diagnosis. It is commonly treated with oral calcium solutions and intravenous calcium borogluconate. Prevention of milk fever is economically important to dairy producers to minimize production losses, death losses and veterinary costs associated with the disease. Multiple strategies have been utilized to prevent hypocalcaemia including feeding anionic salts, low calcium ion diets, vitamin D supplementation, dietary magnesium supplementation, and managing the body condition score of animals during the peripartum period. Hence, prevention of milk fever is the key to reduce the economic impacts of the disease in the dairy industry.
title: Portfolioarbeit als Instrument der Geschichtsdidaktik
Creators: name: Peterseil, Andreas Michael
Year: 2011

description: Die Geschichtsdidaktik wird von den Begriffen Geschichtsbewusstsein und Geschichtskultur geprägt. Nicht zuletzt wurde ein eigenes begriffliches Instrumentarium geschaffen, um sich von der Geschichtswissenschaft abzugrenzen und sich als eigene wissenschaftliche Disziplin zu etablieren. Die Begriffe werden dabei vielfältig rezipiert, ausgebaut und erweitert. Eines der größten Anliegen der Geschichtsdidaktik ist es, für den Unterricht Möglichkeiten und Angebote zu schaffen, die von den Lehrer/innen umgesetzt werden können. Eines dieser Angebote, das bisher noch nicht ausreichend in der Geschichtsdidaktik diskutiert wurde, ist Portfolioarbeit. Damit wird den Schüler/ innen größtmögliche Freiheit in der Themenwahl und -bearbeitung gelassen und dennoch auf Prozessualität und Nachhaltigkeit im Unterricht abgezielt. Im Sinne moderner Didaktik ist diese Selbständigkeit gerade im Fach Geschichte ein wichtiger Bestandteil eines zeitgemäßen Unterrichts. Die vorliegende Arbeit diskutiert zuerst die gängigen Konzepte der Geschichtsdidaktik. Dabei werden nach einem kurzen historischen Überblick die Begriffe Geschichtsbewusstsein und Geschichtskultur zueinander in Beziehung gesetzt. Es wird auch kurz auf moderne Auseinandersetzungen im Zusammenhang mit Geschichtskultur Bezug genommen. Der zweite Teil dieser Studie versucht das Konzept der Portfolioarbeit als vernünftige Ausdrucksweise der Praxis in die Geschichtsdidaktik einzubetten. Zuerst wird das theoretische Konzept von Portfolio vorgestellt. Anhand einer im Gymnasium Wien X durchgeführten Studie (zwei Interviews mit einem Interviewleitfaden mit derselben Befragungsgruppe im Abstand von fünf Monaten) wird versucht, die Auswirkungen des Portfoliounterrichts auf die Schüler/innen zu zeigen. In einem ersten Schritt wird der Unterricht in diesem Zeitraum dokumentiert. Danach werden die Interviews, die mit den Schüler/innen aufgenommen wurden, analysiert und interpretiert. Damit soll in theoretischer Hinsicht die Verankerung von Portfolioarbeit in der Geschichtsdidaktik begründet werden, um in praktischer Hinsicht Rückschlüsse auf die Auswirkungen von Portfoliounterricht auf den Geschichtsunterricht ziehen.
El sector agroquímico y los tratados de libre comercio
Creators: name: Urrea Zuluaga, Sofía
name: Beltrán Vargas, Diana María
Publisher: name: Universidad Externado de Colombia
Year: 2024
Subjects: subject: Tratados comerciales – Colombia
subject: Comercio agrícola - Aspectos económicos - Colombia
subject: Agricultura - Aspectos económicos - Colombia
subject: Agro insumos
subject: Pesticidas
subject: Fertilizantes
subject: Comercio Agrícola
subject: Agricultura
subject: Tratados de Libre Comercio

description: Este capítulo aborda el impacto de los tratados de libre comercio (TLC) en el sector de los agroinsumos colombiano. El impacto se analiza tras un estudio de la balanza de pagos de los últimos 22 años con los principales socios comerciales de Colombia con los que ostenta TLC –Estados Unidos, Canadá, Unión Europea– como con los que no –China y Rusia–. El capítulo analiza el comportamiento de los productos del sector, su inclusión en las listas de desgravación arancelaria y los efectos del fortalecimiento de los derechos de propiedad intelectual en la producción y réplica local mediante patentes y datos de prueba. Los hallazgos revelan una falta de previsión en la negociación de los TLC, evidenciando impactos negativos y costos de oportunidad para el sector nacional de agro-insumos. A pesar de cumplir las metas arancelarias, los cambios en el panorama comercial perjudicaron al sector colombiano, generando un rezago en las exportaciones y mayor dependencia de importaciones. Las primeras secciones presentan un panorama histórico del sector y características de los productos, mientras que las secciones tercera a sexta analizan las balanzas comerciales con socios relevantes. Finalmente, la séptima sección ofrece un diagnóstico del sector colombiano, identificando puntos débiles para considerar en posibles renegociaciones de acuerdos.
description: This chapter addresses the impact of free trade agreements (FTAs) on the Colombian agro-inputs sector. The effect is analyzed by studying the balance of payments over the past 22 years with Colombia’s main trading partners with whom it has FTAs—United States, Canada, and European Union—and those without—China and Russia. The chapter examines the behavior of sector products, their inclusion in tariff reduction lists, and the effects of strengthening intellectual property rights on local production and replication through patents and test data. The findings reveal a lack of foresight in the negotiation of the FTAs, showing negative impacts and opportunity costs for the national agro-inputs sector. Despite meeting tariff goals, changes in the trade landscape have harmed the Colombian industry, causing a lag in exports and increased dependence on imports. The initial sections provide a historical overview of the sector and product characteristics, while sections three to six analyze trade balances with relevant partners. Finally, the seventh section diagnoses the Colombian sector, identifying weaknesses in potential agreement renegotiations.
Fortalecimiento de la competencia uso comprensivo del conocimiento científico a partir de la enseñanza de fenómenos lunares en estudiantes del curso 402 J.M del Colegio Bosanova I.E.D
Creators: name: Maldonado Rincón, Fabio Enrique
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Educación primaria - Metodología
subject: Pedagogía - Enseñanza
subject: Estudiantes - Aspectos sociales
subject: Competencia uso comprensivo del conocimiento científico
subject: Fenómenos lunares
subject: Secuencia didáctica
subject: Centro de interés científico

description: Este trabajo resalta la importancia de fortalecer las competencias científicas en los estudiantes de básica primaria para el abordaje de las problemáticas sociales y ambientales de su contexto. En tal sentido, el objetivo de la presente intervención se enfocó en el fortalecimiento de la competencia “uso comprensivo del conocimiento científico” a través de la enseñanza de los fenómenos lunares, llevada a cabo con los estudiantes del curso 402 de la jornada mañana del Colegio Bosanova IED. Para dicho fin, se implementó una secuencia didáctica de 8 sesiones, centrada en la enseñanza de los fenómenos lunares, en la cual se desarrolló trabajos prácticos de representación y modelización, además del empleo de instrumentos para la observación directa de la luna y el uso de recursos educativos digitales. Dentro del análisis de resultados, se evidenció que los estudiantes lograron reconocer las fases lunares, estableciendo relaciones entre las mareas y el fenómeno gravitatorio, además de comprender la formación de los eclipses y aplicar sus conocimientos a situaciones cotidianas, resaltando la importancia de cultivar habilidades científicas desde su edad temprana. El reto es formar ciudadanos críticos y reflexivos, que produzcan conocimientos, además de aportes a la educación científica colombiana.
description: This work highlights the importance of strengthening scientific skills in primary school students to address social and environmental problems in their context. In this sense, the objective of this intervention focused on strengthening the competence "comprehensive use of scientific knowledge" through the teaching of lunar phenomena, carried out with the students of course 402 of the morning session of the Bosanova School. For this purpose, a didactic sequence of 8 sessions was implemented, focused on the teaching of lunar phenomena, in which practical representation and modeling work was developed, in addition to the use of instruments for direct observation of the moon and the use of digital educational resources. Within the analysis of results, it was evidenced that the students were able to recognize the lunar phases, establishing relationships between the tides and the gravitational phenomenon, in addition to understanding the formation of eclipses and applying their knowledge to everyday situations, highlighting the importance of cultivating scientific skills. from his early age. The challenge is to train critical and reflective citizens, who produce knowledge, as well as contributions to Colombian scientific education.
Periodontitis, age-related diseases and diabetes in an endocrinological outpatient setting (PARADIES): a cross-sectional analysis on predictive factors for periodontitis in a German outpatient facility
Creators: name: Kabisch, Stefan
name: Hedemann, Oda Sophia
name: Pfeiffer, Andreas F. H.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Periodontal disease
subject: Periodontitis
subject: Risk factor
subject: Prediction
subject: Diabetes mellitus
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background Diabetes mellitus (DM) is a risk factor for periodontitis. Data on risk-modifying factors for periodontitis in diabetes patients are limited. Aims We tested whether sex, age, type of diabetes, metabolic state, comorbidities, complications, measures of well-being and quality of life are predicting periodontitis in a German diabetes outpatient cohort. Methods In total, 1180 out of 1293 participating DM patients completed questionnaires on quality of life, dental hygiene and health. All patients also filled out a modified version of the periodontitis risk questionnaire by the American Association for Periodontology, from which the status of "assumed periodontitis" was deducted. In a subset of participants (n = 461), we measured or inquired the most recent Community Parodontal Index (CPI), providing an objective measure for clinically diagnosed periodontitis. For all subjects, DM history and phenotype, major metabolic parameters (HbA1c, BMI, LDL and total cholesterol levels), general health risk factors, comorbidities and medication were collected. Results Clinically diagnosed (CPI > 2) and assumed periodontitis was detected in 60-67% of our patients. Male sex and oral health-related quality of life were associated with clinically diagnosed periodontitis. Male sex, age, smoking, dental hygiene, dental control and diabetes-related quality of life independently predicted assumed periodontitis. Conclusion In DM patients, quality of life and lifestyle factors which systemically alter microvascular and immunological functions seem to predict periodontitis. Further studies are needed for replication and for pathomechanistic clarification.
Softwood Lumber – Some Lessons from the Last Softwood (Lumber IV) Dispute
Creators: name: Feldman, Elaine
Publisher: name: The School of Public Policy Publications
Year: 2017

description: The checkered history of softwood lumber disputes between Canada and its southern neighbour stretches back to the 1800s, with five of them occurring since 1982. Two years ago, the settlement obtained in 2006 expired and most Canadian softwood lumber exporters now face a combined countervailing and anti-dumping duty rate from the Americans of around 27 per cent. On the surface, the last dispute, known as Lumber IV, appeared to be a squabble over subsidization and dumping of Canadian softwood lumber exports. However, closer scrutiny revealed that this dispute was really about commercial interests triumphing over policy – the U.S. lumber industry wanted to ensure it kept a certain share of the market at the highest price possible. Complicating attempts to resolve any dispute is the fact that Canada is not a single entity in the lumber business; interest in quota or duties varies across regions as do the countervailing (CVD) and anti-dumping (AD) rates that the U.S. imposes on particular Canadian producers. These variations thus create almost a divide-and-conquer situation in which one group of producers feels others are getting an advantage. The Canadian industry instead should be standing together as much as possible, creating a united front in any dispute with the U.S. Drafting new policy and resorting to litigation to settle Lumber IV failed because the potential settlement got bogged down by the drawbacks of both of those routes. Policy failed because it quickly became clear that the U.S. was going to act with impunity to determine whether there was a subsidy, regardless of what the trade rules permitted. And litigation created an endless loop in which contradictory rulings were handed back and forth between NAFTA panels and the U.S. International Trade Commission, stalling any resolution. Lumber IV also taught the Canadians that taking their complaints to both NAFTA and the World Trade Organization, which does not order a refunding of wrongly collected duties, only further muddied the hoped-for outcome. It took political will on the part of both the U.S. and Canada to finally reach a solution. Nevertheless, Chapter 19 of NAFTA played a key role in establishing the 2006 softwood lumber accord between the U.S. and Canada, and the return to Canada of approximately $4 billion of the $5 billion worth of duties deemed to have been wrongly collected by the Americans. A renegotiation of NAFTA that would see the elimination of Chapter 19, which the U.S. has called for, would make the settlement of Lumber V much more difficult, politicized and litigious. The absence of Chapter 19 could also threaten other Canadian industries should the U.S. proceed with industry requests to impose CVD and/or AD duties (Boeing and its complaint against Bombardier being the most recent example).
description: The School of Public Policy Publications, Vol 10 (2017)
Isara H. Adams & A. Adams 1853
Creators: name: Harzhauser, Mathias
name: Landau, Bernard
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Mitridae
Isara

description: Genus Isara H. Adams & A. Adams, 1853
Type species. Mitra bulimoides Reeve, 1845 [= M. glabra Swainson, 1821], subsequent designation by Cossmann (1899: 153). Present-day, Indo-West Pacific.
Diagnosis. “ Shell medium sized to large (30–100 mm), fusiform to turriform, lightly sculptured, light or dark brown due to well-developed periostracum. Suture distinct, impressed. Spire high to very high; teleoconch whorls gently convex to flattened, sculptured by regular or occasional spiral grooves, or smooth, often with a microsculpture of fine collabral growth lines. Siphonal canal short with well-developed fasciole to moderately long and tapering. Siphonal notch shallow or absent. Aperture elongate, rather wide; outer aperture lip evenly convex or straight in its adapical portion and strongly convex anteriorly. Inner lip with four columellar folds, the anteriormost notably weaker ” (Fedosov et al., 2018: 65).
Discussion. As discussed by Fedosov et al. (2018) it is impossible to separate Episcomitra and Isara based on conchological features alone. Therefore, some of the species placed herein in Episcomitra might belong to Isara. Herein, we place only Mitra hoernesi Mayer, 1864 in Isara, as it is morphologically closely similar to the presentday Isara cornea (Lamarck, 1811).
Present-day distribution. Isara has a wide distribution including the Western Mediterranean Sea, the Azores, the Caribbean, West Africa and the Indo-Pacific (Fedosov et al. 2018).
description: Published as part of Harzhauser, Mathias & Landau, Bernard, 2021, The Mitridae (Gastropoda: Neogastropoda) of the Miocene Paratethys Sea, pp. 1-72 in Zootaxa 4983 (3) on page 43, DOI: 10.11646/zootaxa.4983.1.1, http://zenodo.org/record/4921887
Severe Traumatic Brain Injury in children—paradigm of decompressive craniectomy compared to a historic cohort
Creators: name: Hubertus, Vanessa
name: Finger, Tobias
name: Drust, Ricarda
name: Al Hakim, Sara
name: Schaumann, Andreas
name: Schulz, Matthias
name: Gratopp, Alexander
name: Thomale, Ulrich-Wilhelm
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Pediatric traumatic brain injury
subject: Severe TBI
subject: Intracranial pressure
subject: Decompressive craniectomy
subject: Glasgow outcome score
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Purpose Traumatic brain injury (TBI) is one of the leading causes of death and disability in children. Medical therapy remains limited, and decompressive craniectomy (DC) is an established rescue therapy in case of elevated intracranial pressure (ICP). Much discussion deals with clinical outcome after severe TBI treated with DC, while data on the pediatric population is rare. We report our experience of treating severe TBI in two different treatment setups at the same academic institution. Methods Forty-eight patients (<= 16 years) were hospitalized with severe TBI (GCS <= 8 points) between 2008 and 2018 in a pediatric intensive care unit (ICU) at a specialized tertiary pediatric care center. Data on treatment, clinical status, and outcome was retrospectively analyzed. Outcome data included Glasgow Outcome Scale (GOS) at 3-, 12-, and 36-month follow-up. Data was compared to a historic cohort with 53 pediatric severe TBI patients treated at the same institution in a neurointensive care unit between 1996 and 2007. Ethical approval was granted (EA2/076/21). Results Between 2008 and 2018, 11 patients were treated with DC. Compared to the historic cohort, patients were younger and GCS was worse, while in-hospital mortality and clinical outcome remained similar. A trend towards more aggressive EVD placement and the internal paradigm change for treatment in a specialized pediatric ICU was observed. Conclusions In children with severe TBI treated over two decades, clinical outcome was comparable and mostly favorable in two different treatment setups. Consequent therapy is warranted to maintain the positive potential for favorable outcome in children with severe TBI.
Biology of house dust mites and storage mites
Creators: name: Bergmann, Karl-Christian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: House mites
subject: house dust mites
subject: storage mites
subject: biology
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: House dust mites and storage mites have a high allergenic potential and lead to sensitization through the formation of specific IgE antibodies. Due to their preferred stay in houses, they belong to the group of house mites, which are referred to as "domestic mites" in the English-speaking world.Their anatomy and biology justify their astonishing adaptability to changing environmental situations (e.g. temperature, humidity, food) and make it understandable that measures to reduce their frequency are usually difficult to implement in practice.
MPEC 2024-Q20 : OBSERVATIONS AND ORBITS OF COMETS AND A/ OBJECTS
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: OBSERVATIONS AND ORBITS OF COMETS AND A/ OBJECTS

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Positive and negative DC glow discharges: a comparative study to characterize self-organized patterns on water surface
Creators: name: Dufour, Thierry
name: Ogden, Elliot
Publisher: name: arXiv
Year: 2025
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences

description: Self-organized patterns (SOP) in plasma discharges arise from the complex interplay of electric field, reactive species and charged particles, driven by non-linear plasma dynamics. While studies have explored SOP formation in various configurations, no systematic comparison of positive and negative DC glow discharges has been conducted to explain why SOP form exclusively when polarization is negative. This study aims to analyze SOP formation mechanisms by comparing electrical, optical and spectral properties of positive and negative DC glow discharges interacting with a grounded water surface. Key differences in gas temperature, electric field and reactive species distribution are hence identified. For positive DC glow discharges (PGD), the gas temperature remains in the 350-370 K range, while the reduced electric field remains below 100 Td across the gap. The plasma is dominated by OH and N2* species, whose excitation results from direct electron impact and energy transfer in a low-field environment. The absence of strong ionization and electric field gradients leads to a spatially homogeneous emission layer on the liquid surface, resulting in a circular uniform plasma (CUP) pattern without self-organization. In contrast, SOP emerge exclusively under negative DC glow discharges (NGD) at currents above 15 mA. These discharges present a reduced electric field, peaking at 485 Td at 1mm from the cathode pin, dropping below 100 Td in the central gap and rising to 460 Td near the water surface. There, the plasma layer still contains OH and N2* species but also N2+ ions, the latter being critical for SOP formation. SOP morphology evolves with gap size: at 7 mm, patterns transition from specks to filaments, with pattern diameter and thickness as high as 5.5 mm and 210 μm respectively. Lowering water surface tension with surfactants reduces SOP size and modifies pattern morphology.
Nebularia Swainson 1840
Creators: name: Harzhauser, Mathias
name: Landau, Bernard
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Mitridae
Nebularia

description: Genus Nebularia Swainson, 1840
Type species. Mitra contracta Swainson, 1820; subsequent designation by Herrmannsen (1847: 110). Present-day, Indo-West Pacific.
Diagnosis. “ Shell small to large (15–150 mm), fusiform to elongate-fusiform. Protoconch pointed, narrowly conical, of three or more slightly convex, smooth and glossy whorls. Teleoconch whorls usually flattened in outline, with orthoconoid or acuminate spire. Sculpture variable, from indistinct to strong and deep groves separating flattened or rounded, sometimes undulating cords. Siphonal canal robust, short to moderately long, sometimes with distinct fasciole, giving siphonal canal a recurved appearance. Aperture elongate, its outer lip often thickened in its adapical portion. Margin of outer lip smooth or bearing fine denticles throughout its length. Inner lip with four to five delicate folds of subequal strength ” (Fedosov et al., 2018: 62).
Discussion. The placement of the Paratethyan Nebularia soliphila nov. sp. in Nebularia is based on the short aperture, gradate spire, solid outer lip and prominent, twisted fasciole, which exclude placement in the genus Cancilla Swainson, 1840. Moreover, Cancilla is a deep water genus, whereas Nebularia is found in intertidal and shallow sublittoral environments (Fedosov et al. 2018). The extant Nebularia incompta [Lightfoot, 1786], from the presentday Indo-West Pacific, is almost identical to Nebularia soliphila nov. sp., but with more numerous spiral cords.
Present-day distribution. Indo-West Pacific (Fedosov et al. 2018).
description: Published as part of Harzhauser, Mathias & Landau, Bernard, 2021, The Mitridae (Gastropoda: Neogastropoda) of the Miocene Paratethys Sea, pp. 1-72 in Zootaxa 4983 (3) on page 46, DOI: 10.11646/zootaxa.4983.1.1, http://zenodo.org/record/4921887
Understanding the Patient Experience of Hunger and Improved Quality of Life with Setmelanotide Treatment in POMC and LEPR Deficiencies
Creators: name: Wabitsch, Martin
name: Fehnel, Sheri
name: Mallya, Usha G.
name: Sluga-O’Callaghan, Martina
name: Richardson, David
name: Price, Mark
name: Kühnen, Peter
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Disease Burden
subject: Hyperphagia
subject: Leptin Receptor
subject: Melanocortin Receptor
subject: Pro-Opiomelanocortin
subject: Rare Genetic Diseases of Obesity
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Introduction In patients with pro-opiomelanocortin (POMC) or leptin receptor (LEPR) deficiency, managing obesity and hyperphagia can be burdensome for patients and caretakers. The impacts on health-related quality of life are under-recognized and are not well characterized. Methods We conducted in-depth qualitative interviews in patients with POMC (n = 3) and LEPR (n = 2) deficiencies participating in an ongoing open-label extension of phase 3 clinical trials with the melanocortin receptor 4 agonist setmelanotide to describe the patient experience of hyperphagia and characterize changes following treatment with setmelanotide. Results Prior to setmelanotide treatment, all five patients described abnormal sensations of hunger with none indicating feeling satiated after meals and also reported that the burden of hyperphagia impacted their families, emotions, and work and/or school functioning. Following setmelanotide treatment, all five patients reported consistent reductions in hunger and weight, decreased eating, and feeling satiated after meals in addition to substantial improvements in each area of functioning they had previously reported. All five patients indicated they were very satisfied with the impact of setmelanotide on their quality of life and would be upset if treatment was discontinued. Conclusions In patients with POMC or LEPR deficiency, hyperphagia and the inability to feel satiety negatively impacted quality of life. By reducing hunger and improving satiety, setmelanotide facilitated important changes in the lives of these patients. This qualitative research study suggests that the impact of setmelanotide goes beyond favorable clinical changes (e.g., weight and hunger) to also include quality of life improvements that are highly meaningful to patients.
Physics at Future Colliders - Experimental Physics at Future Colliders
Creators: name: Borras, Kerstin
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2017

description: 2nd CMS Workshop "Perspectives on Physics and on CMS at HL-LHC", 2ndCMSWorkshopHL-LHC, Varna, Bulgaria, 29 Aug 2017 - 1 Sep 2017
Collinear and TMD Quark and Gluon Densities from Parton Branching Solution of QCD Evolution Equations
Creators: name: Hautmann, F.
name: Jung, Hannes
name: Lelek, A.
name: Radescu, V.
name: Zlebcik, R.
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2017
Subjects: parton: density
parton: distribution function
distribution function: transverse momentum dependence
quantum chromodynamics: perturbation theory: higher-order
higher-order: 1
evolution equation
deep inelastic scattering: structure function

description: We study parton-branching solutions of QCD evolution equations and present a method to construct both collinear and transverse momentum dependent (TMD) parton densities from this approach. We work with next-to-leading-order (NLO) accuracy in the strong coupling. Using the unitarity picture in terms of resolvable and non-resolvable branchings, we analyze the role of the soft-gluon resolution scale in the evolution equations. For longitudinal momentum distributions, we find agreement of our numerical calculations with existing evolution programs at the level of better than 1 percent over a range of five orders of magnitude both in evolution scale and in longitudinal momentum fraction. We make predictions for the evolution of transverse momentum distributions. We perform fits to the high-precision deep inelastic scattering (DIS) structure function measurements, and we present a set of NLO TMD distributions based on the parton branching approach.
Transferred plasma catheter for endotherapeutic applications: a parametric study of guided streamers dynamics
Creators: name: Soulier, M.
name: Vacek, T.
name: Geraud, K.
name: Dufour, T.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Medical Physics (physics.med-ph)
subject: FOS: Physical sciences

description: Non-thermal atmospheric pressure plasma jets (APPJs) are increasingly used in biomedical applications due to their low temperatures and ability to generate reactive oxygen and nitrogen species (RONS), making them suitable for sensitive environments like medical therapies. The transferred plasma catheter (TPC), a variant of APPJ, shows promise for endoscopic applications but requires precise control of plasma dynamics in confined spaces to ensure safety and efficacy. Despite extensive studies on guided streamers in traditional APPJs, there is limited understanding of streamer behavior in TPC configurations, particularly in challenging scenarios involving grounded metallic surfaces. This study examines the spatiotemporal dynamics of guided streamers generated by TPCs under varying gap distances to establish a robust framework for safe and effective plasma delivery in endoscopic settings. Combining electrical and optical diagnostics, the study characterizes streamer propagation, electric field profiles, and plasma-induced currents in a helium-driven TPC delivering cold plasma to a grounded metal target across gaps of 2 to 18 mm. Results show that streamers maintain charge stability and effectively interact with the target for gap distances below 12 mm, producing significant therapeutic currents. Beyond this threshold, propagation deteriorates due to recombination and reduced electric field intensity. For shorter gaps, counter-propagating waves and secondary streamer interactions are observed, while larger gaps lead to charge dissipation and reduced efficacy. These findings highlight the importance of optimizing gap distances for plasma-assisted endoscopic procedures and demonstrate the TPC's robustness in adverse conditions.
EVALUATION OF ACADEMIC ETHICS AMONG STUDENTS IN THE UTILIZATION OF GENERATIVE ARTIFICIAL INTELLIGENCE FOR SELF-DIRECTED LEARNING
Creators: name: Tamaris, Sabrina
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 460208
subject: Natural language processing
classificationCode: 390303
subject: Higher education

description: The use of Generative Artificial Intelligence (ChatGPT) in education has become an increasingly relevant and interesting topic in an era of ever-evolving information technology and artificial intelligence. This background reflects the importance of a comprehensive understanding of the benefits and risks of using ChatGPT in an educational context and the need for strong ethical guidelines to guide the use of this technology in a way that supports quality and ethical learning. This research presents a bibliometric analysis using the Scopus database. The search phrase consisted of the words ‘generative artificial intelligence’ or ‘generative ai’ AND ethics, ethics, education, or education. After obtaining raw data from 115 journals, the data was filtered to 72 journals to be used as research material retrieved using Mendeley. After that, a total of 12 keywords were found, focusing on the challenges and opportunities in integrating Generative AI into education, including ethics and bias and academic integrity of universities. thus finding Challenges from the application of Generative AI in the field of education, such as ethical issues and academic integration faced in the use of generative AI in higher education are also discussed.
Sustainable Feedstocks For Advanced Biofuel Production In Europe
Creators: name: German, Lizzie
Publisher: name: Zenodo
Year: 2017
Subjects: biofuel
fermentation
miscanthus
municipal solid waste
wheat straw
pilot plant

description: Biobutanol is an exciting alternative to first generation biofuels due to its physical and chemical characteristics, making it more fuel efficient and suitable for use in spark ignition and diesel engines without the need for modification. However, due to the inefficiencies and costs associated with the current production process, biobutanol is yet to gain market establishment. The ButaNexT project will develop highly efficient production processes for the conversion of sustainable feedstocks into the next generation biobutanol. This will contribute to overcoming the current challenges and limitations exhibited by first generation biofuels. The ButaNexT consortium is a multi-disciplinary team of SMEs, large companies and research centres from Belgium, the Netherlands, Spain and the United Kingdom. The team aspires to optimise each stage of the biobutanol production value chain: biomass pre-treatment, enzymatic hydrolysis, fermentation, downstream processing and blending. It is expected that ButaNexT will achieve significant reductions in both production costs (up to 50%, to attain price-parity with first generation biofuels) and carbon emissions (up to 85%) compared with fossil fuels (gasoline and diesel). Moreover, the project is working on maximising the biobutanol conversion yields from selected lignocellulosic feedstocks such as wheat straw, miscanthus and the organic fraction of Municipal Solid Waste.
SepAl: Sepsis Alerts On Low Power Wearables With Digital Biomarkers and On-Device Tiny Machine Learning
Creators: name: Giordano, Marco
name: Dheman, Kanika
name: Magno, Michele
Publisher: name: arXiv
Year: 2024
Subjects: subject: Tissues and Organs (q-bio.TO)
subject: Machine Learning (cs.LG)
subject: FOS: Biological sciences
subject: FOS: Computer and information sciences

description: Sepsis is a lethal syndrome of organ dysfunction that is triggered by an infection and claims 11 million lives per year globally. Prognostic algorithms based on deep learning have shown promise in detecting the onset of sepsis hours before the actual event but use a large number of bio-markers, including vital signs and laboratory tests. The latter makes the deployment of such systems outside hospitals or in resource-limited environments extremely challenging. This paper introduces SepAl, an energy-efficient and lightweight neural network, using only data from low-power wearable sensors, such as photoplethysmography (PPG), inertial measurement units (IMU), and body temperature sensors, designed to deliver alerts in real-time. SepAl leverages only six digitally acquirable vital signs and tiny machine learning algorithms, enabling on-device real-time sepsis prediction.
 SepAl uses a lightweight temporal convolution neural network capable of providing sepsis alerts with a median predicted time to sepsis of 9.8 hours. The model has been fully quantized, being able to be deployed on any low-power processors, and evaluated on an ARM Cortex-M33 core. Experimental evaluations show an inference efficiency of 0.11MAC/Cycle and a latency of 143ms, with an energy per inference of 2.68mJ. This work aims at paving the way toward accurate disease prediction, deployable in a long-lasting multi-vital sign wearable device, suitable for providing sepsis onset alerts at the point of care.
 The code used in this work has been open-sourced and is available at https://github.com/mgiordy/sepsis-prediction
Risk Assessment Framework for Code LLMs via Leveraging Internal States
Creators: name: Huang, Yuheng
name: Ma, Lei
name: Nishikino, Keizaburo
name: Akazaki, Takumi
Publisher: name: arXiv
Year: 2025
Subjects: subject: Software Engineering (cs.SE)
subject: Artificial Intelligence (cs.AI)
subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: The pre-training paradigm plays a key role in the success of Large Language Models (LLMs), which have been recognized as one of the most significant advancements of AI recently. Building on these breakthroughs, code LLMs with advanced coding capabilities bring huge impacts on software engineering, showing the tendency to become an essential part of developers' daily routines. However, the current code LLMs still face serious challenges related to trustworthiness, as they can generate incorrect, insecure, or unreliable code. Recent exploratory studies find that it can be promising to detect such risky outputs by analyzing LLMs' internal states, akin to how the human brain unconsciously recognizes its own mistakes. Yet, most of these approaches are limited to narrow sub-domains of LLM operations and fall short of achieving industry-level scalability and practicability. To address these challenges, in this paper, we propose PtTrust, a two-stage risk assessment framework for code LLM based on internal state pre-training, designed to integrate seamlessly with the existing infrastructure of software companies. The core idea is that the risk assessment framework could also undergo a pre-training process similar to LLMs. Specifically, PtTrust first performs unsupervised pre-training on large-scale unlabeled source code to learn general representations of LLM states. Then, it uses a small, labeled dataset to train a risk predictor. We demonstrate the effectiveness of PtTrust through fine-grained, code line-level risk assessment and demonstrate that it generalizes across tasks and different programming languages. Further experiments also reveal that PtTrust provides highly intuitive and interpretable features, fostering greater user trust. We believe PtTrust makes a promising step toward scalable and trustworthy assurance for code LLMs.
description: To appear in the 33rd ACM International Conference on the Foundations of Software Engineering (FSE Companion'25 Industry Track), June 23-28, 2025, Trondheim, Norway. This work was supported by Fujitsu Limited
Frequency of sensitizations and allergies to house dust mites
Creators: name: Bergmann, Karl-Christian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: House mites
subject: house dust mites
subject: storage mites
subject: sensitization
subject: epidemiology
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: House dust mites and storage mites are grouped together under the name "domestic mites". As a result, mites can trigger allergic diseases of the upper and lower respiratory tract as well as cross-reactions to other allergens. Sensitization to house mites is widespread in the German population. Around eleven million adults in Germany are sensitized (15.9%). Men are affected more often than women, and sensitization occurs more frequently in large cities and in those with a higher socioeconomic status. Sensitizations are less common in old age. As clinically silent sensitizations, they can lead to diagnostic problems, which is the case with about 40% of sensitizations.
90-yttrium-ibritumomab tiuxetan as first-line treatment for follicular lymphoma: updated efficacy and safety results at an extended median follow-up of 9.6 years
Creators: name: Rieger, Kathrin
name: De Filippi, Rosaria
name: Lindén, Ola
name: Viardot, Andreas
name: Hess, Georg
name: Lerch, Kristina
name: Neumeister, Peter
name: Stroux, Andrea
name: Peuker, Caroline A.
name: Pezzutto, Antonio
name: Pinto, Antonello
name: Keller, Ulrich
name: Scholz, Christian W.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Follicular lymphoma
subject: First-line therapy
subject: 90-yttrium-ibritumomab tiuxetan
subject: 90Y-IT
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Radioimmunotherapy with 90-yttrium-ibritumomab tiuxetan (90Y-IT) as first-line treatment in patients with follicular lymphoma (FL) demonstrated promising results with a complete remission (CR) rate of 56% and a median progression-free survival (PFS) of 26 months, when initially analyzed after a median follow-up of 30.6 months. The aim of this long-term follow-up was to investigate whether clinical benefits were maintained and new safety signals appeared. Fifty-nine patients, aged >= 50 years, with FL grade 1 to 3A in stages II to IV were treated with 90Y-IT as first-line therapy. If CR without evidence of minimal residual disease (MRD), partial response or stable disease was achieved 6 months after treatment, patients were observed without further treatment. Patients with CR but persisting MRD received consolidation therapy with rituximab. The primary endpoint was the clinical response rate. Secondary endpoints were time to progression, safety, and tolerability. After a median follow-up of 9.6 years, median PFS was 3.6 years, and 8-year PFS was 38.3%. Median overall survival (OS) was not reached during the extended follow-up, and 8-year OS amounted to 69.2%. Age 65 years and above or disease progression within 24 months of treatment were significantly associated with shorter OS. An important finding was the lack of new safety signals. In particular, no increase in secondary malignancies or transformation into aggressive lymphoma was observed compared to trials with a similar follow-up. In summary, 90Y-IT as first-line treatment demonstrates a favorable safety profile and long-term clinical activity in a substantial fraction of FL patients in need of therapy. ClinicalTrials.gov Identifier: NCT00772655.