cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Evaluation of ultra high-performance liquid chromatography (uHPLC) assisted capsaicinoids content in four different extracts of (Capsicum chinense Jacq.): their pharmacological potentials and genotoxicity study
Creators: name: Bhandari, Sangeeta
name: Gogoi, Roktim
name: Begum, Twahira
name: Baruah, Joyashree
name: Lal, Mohan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: Plant Biology

description: The present study determined the capsaicin, dihydrocapsaicin and nordihydrocapsaicin of Capsicum chinense Jacq., ethanol, methanol, acetonitrile and dry acetone extracts using ultra high-performance liquid chromatography (uHPLC) technique. Highest capsaicin (2.84%) and nordihydrocapsaicin (0.56%) content was recorded in ethanol extract, while methanol extracts constituted highest dihydrocapsaicin (1.27%). Strong anti-inflammatory activity was shown by ethanol extract. All the extracts were found to be weak anti-diabetic, skin whitening and neurodegenerative agent. In genotoxicity test, ethanol extract showed mitotic index (MI) of 13.16% which was close to distilled water 25.72%. The chromosomal aberration of 8.0% was shown by ethanolic extract. The mitotic index value and chromosome aberration percentages of all the four extracts were similar but far from positive mutagenic agent ethyl methane sulfonate. Ethanol extract proved to be the best solvent for capsaicinoids extraction in comparison to the other three solvents and emerged as a potential pharmacological candidate having excellent anti-inflammatory ability.
Mechanisms during Osteogenic Differentiation in Human Dental Follicle Cells
Creators: name: Morsczeck, Christian
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: dental follicle cells; osteogenic differentiation; signaling pathways; tooth development; tooth eruption
subject: 610 Medizin

description: Human dental follicle cells (DFCs) as periodontal progenitor cells are used for studies and research in regenerative medicine and not only in dentistry. Even if innovative regenerative therapies in medicine are often considered the main research area for dental stem cells, these cells are also very useful in basic research and here, for example, for the elucidation of molecular processes in the differentiation into mineralizing cells. This article summarizes the molecular mechanisms driving osteogenic differentiation of DFCs. The positive feedback loop of bone morphogenetic protein (BMP) 2 and homeobox protein DLX3 and a signaling pathway associated with protein kinase B (AKT) and protein kinase C (PKC) are presented and further insights related to other signaling pathways such as the WNT signaling pathway are explained. Subsequently, some works are presented that have investigated epigenetic modifications and non-coding ncRNAs and their connection with the osteogenic differentiation of DFCs. In addition, studies are presented that have shown the influence of extracellular matrix molecules or fundamental biological processes such as cellular senescence on osteogenic differentiation. The putative role of factors associated with inflammatory processes, such as interleukin 8, in osteogenic differentiation is also briefly discussed. This article summarizes the most important insights into the mechanisms of osteogenic differentiation in DFCs and is intended to be a small help in the direction of new research projects in this area
title: Significance and utility of selective tributary sampling for accurate diagnosis of unilateral primary aldosteronism.
Creators: name: kobayashi, masahiro
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Interventional vascular
subject: Catheter venography
subject: Sampling
subject: Endocrine disorders

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: ・To understand the indications of AVS. ・To understand the anatomy of the intra-adrenal vein, appropriate sampling sites according to patient’s anatomical vascular variations. ・To understand how to evaluate the laboratory data obtained from...
White dwarf-main sequence binaries from LAMOST: the DR1 catalogue
Creators: name: Ren, Juanjuan
name: Rebassa-Mansergas, Alberto
name: Luo, Ali
name: Zhao, Yongheng
name: Xiang, Maosheng
name: Liu, Xiaowei
name: Zhao, Gang
name: Jin, Ge
name: Zhang, Yong
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Context. White dwarf-main sequence (WDMS) binaries are used to study several different important open problems in modern astrophysics. Aims. The Sloan Digital Sky Survey (SDSS) identified the largest catalogue of WDMS binaries currently known. However, this sample is seriously affected by selection effects and the population of systems containing cool white dwarfs and early-type companions is under-represented.Here we search for WDMS binaries within the spectroscopic data release 1 of the LAMOST (Large sky Area Multi-Object fiber Spectroscopic Telescope) survey. LAMOST and SDSS follow different target selection algorithms. Hence, LAMOST WDMS binaries may be drawn from a different parent population and thus help in overcoming the selection effects incorporated by SDSS on the current observed population. Methods. We develop a fast and efficient routine based on the wavelet transform to identify LAMOST WDMS binaries containing a DA white dwarf and a M dwarf companion, and apply a decomposition/fitting routine to their LAMOST spectra to estimate their distances and measure their stellar parameters, namely the white dwarf effective temperatures, surface gravities and masses, and the secondary star spectral types. Results. We identify 121 LAMOST WDMS binaries, 80 of which are new discoveries, and estimate the sample to be \sim90 per cent complete. The LAMOST and SDSS WDMS binaries are found to be statistically different. However, this result is not due to the different target selection criteria of both surveys, but likely a simple consequence of the different observing conditions. Thus, the LAMOST population is found at considerably shorter distances (\sim50-450 pc) and is dominated by systems containing early-type companions and hot white dwarfs. (abridged)
description: 14 pages, 8 figures, accepted for publication in A&A
title: Multiphasic Gd-EOB-DTPA magnetic resonance in diagnosis of HCCs in patients underwent liver transplantation
Creators: name: Zhang, Jie
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Liver
subject: Abdomen
subject: MR
subject: Contrast agent-intravenous
subject: Transplantation

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Normal 0 7.8 磅 0 2 false false false EN-US ZH-CN X-NONE To investigate the role of the hepatocyte-specific agent Gd-EOB-DTPA MRI on multi-phase in characterizing HCCs in explanted liver...
title: Autoimmune thyroiditis: Sonographic pattern and keys for a correct diagnosis
Creators: name: García Sánchez, María Jesús
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Thyroid / Parathyroids
subject: Ultrasound
subject: Puncture
subject: Endocrine disorders

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: -To review the anatomy and the sonographic appearance of the normal thyroid gland. -To describe the sonographic broad spectrum of autoimmune thyroiditis, emphasizing on a key finding for correct diagnosis: perithyroidal lymph...
A spring-block analogy for the dynamics of stock indexes
Creators: name: Sandor, Bulcsu
name: Neda, Zoltan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Physics and Society (physics.soc-ph)
subject: General Finance (q-fin.GN)
subject: FOS: Physical sciences
subject: FOS: Economics and business

description: A spring-block chain placed on a running conveyor belt is considered for modeling stylized facts observed in the dynamics of stock indexes. Individual stocks are modeled by the blocks, while the stock-stock correlations are introduced via simple elastic forces acting in the springs. The dragging effect of the moving belt corresponds to the expected economic growth. The spring-block system produces collective behavior and avalanche like phenomena, similar to the ones observed in stock markets. An artificial index is defined for the spring-block chain, and its dynamics is compared with the one measured for the Dow Jones Industrial Average. For certain parameter regions the model reproduces qualitatively well the dynamics of the logarithmic index, the logarithmic returns, the distribution of the logarithmic returns, the avalanche-size distribution and the distribution of the investment horizons. A noticeable success of the model is that it is able to account for the gain-loss asymmetry observed in the inverse statistics. Our approach has mainly a pedagogical value, bridging between a complex socio-economic phenomena and a basic (mechanical) model in physics.
description: 11 pages 9 figures
A Flow in the Forest
Creators: name: Gorsky, Alexander
name: Kazakov, Vladimir
name: Levkovich-Maslyuk, Fedor
name: Mishnyakov, Victor
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Using the matrix-forest theorem and the Parisi-Sourlas trick we formulate and solve a one-matrix model with non-polynomial potential which provides perturbation theory for massive spinless fermions on dynamical planar graphs. This is a lattice version of 2d quantum gravity coupled to massive spinless fermions. Our model equivalently describes the ensemble of spanning forests on the same graphs. The solution is formulated in terms of an elliptic curve. We then focus on a near-critical scaling limit when both the graphs and the trees in the forests are macroscopically large. In this limit we obtain universal one-point scaling functions (condensates), parameterized in terms of the Lambert function. Our results provide a rare example where one can explore the flow between two gravity models -- in this case, the theories of conformal matter coupled to 2d gravity with c=-2 (large trees regime) and c=0 (small trees regime). We also compute the disc partition functions with Dirichlet and Neumann boundary conditions in the same critical limit.
description: 49 pages; v2: results on phi^3 correlator added, minor corrections
title: Automated size and volumetric evaluation of pulmonary nodule using computer-aided diagnosis: influence of radiation dose and reconstruction technique of computed tomography
Creators: name: Ha, Tae Yang
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Computer Applications-Detection, diagnosis
subject: CAD
subject: CT
subject: CAD
subject: Thorax
subject: Computer applications
subject: Cancer
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Low dose CT is proven to be efficient in the lung-cancer screening of high risk patient group. However, to detect the small nodule and evaluate follow-up study is repetitive and boring daily work for the thoracic radiologists. The CAD system can...
A review of the phytochemistry, ethnopharmacology and biological activities of Teucrium genus (Germander)
Creators: name: Sadeghi, Zahra
name: Yang, Jun-Li
name: Venditti, Alessandro
name: Farimani, Mahdi Moridi
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Teucrium L (Lamiaceae) is mainly distributed in the Mediterranean area. A comprehensive survey in the electronic databases (during 2000–2020 years) with keywords of ‘Teucrium’ and ‘Germander’ showed that chemical analyses are available for 27 species, with sesquiterpenoids, iridoids, di and triterpenoids, and phenolic compounds as identified structures. The neo-clerodane diterpenoids as potential chemotaxonomic markers were the main compounds of this genus. As a result, Italy and Turkey have good attempts at phytochemical analysis. The pharmacological activities of different species including antioxidant, cytotoxic activity, antidiabetic, antimicrobial, anti-inflammatory and anti-insect have been summarized. Teucrium polium and Teucrium chamaedrys mainly have been used in digestive problems and diabetes in traditional medicine. Evidence-based clinical trials are needed to confirm the therapeutic properties of this genus. As well to the popularity of Asian and Anatolian species as ingredients in contemporary medicines and products, further research is required in comparison to European species.
A probabilistic framework for uncertainty quantification in positron emission particle tracking
Creators: name: Offner, Avshalom
name: Manger, Sam
name: Vanneste, Jacques
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences

description: Positron Emission Particle Tracking (PEPT) is an imaging method for the visualization of fluid motion, capable of reconstructing three-dimensional trajectories of small tracer particles suspended in nearly any medium, including fluids that are opaque or contained within opaque vessels. The particles are labeled radioactively, and their positions are reconstructed from the detection of pairs of back-to-back photons emitted by positron annihilation. Current reconstruction algorithms are heuristic and typically based on minimizing the distance between the particles and the so-called lines of response (LoRs) joining the detection points, while accounting for spurious LoRs generated by scattering. Here we develop a probabilistic framework for the Bayesian inference and uncertainty quantification of particle positions from PEPT data. We formulate a likelihood by describing the emission of photons and their noisy detection as a Poisson process in the space of LoRs. We derive formulas for the corresponding Poisson rate in the case of cylindrical detectors, accounting for both undetected and scattered photons. We illustrate the formulation by quantifying the uncertainty in the reconstruction of the position of a single particle on a circular path from data generated by state-of-the-art Monte Carlo simulations. The results show how the observation time $Δt$ can be chosen optimally to balance the need for a large number of LoRs with the requirement of small particle displacement imposed by the assumption that the particle is static over $Δt$. We further show how this assumption can be relaxed by inferring jointly the position and velocity of the particle, with clear benefits for the accuracy of the reconstruction.
Chemical constituents from the aerial part of Polygala tenuifolia
Creators: name: Cheng, Yan-Gang
name: Tan, Jin-Yan
name: Li, Jian-Li
name: Wang, Shi-Hui
name: Liu, Kai-Li
name: Wang, Jia-Min
name: Wang, Ying-Li
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Three new compounds, polygalapyrone A (1), tenuiside G (2) and polygalapyrrole A (3), together with two known compounds (4–5) were isolated by silica gel, ODS and preparative HPLC from the aerial part of Polygala tenuifolia. Their structures were elucidated by spectrum analysis and compared with findings from the literature. The anti-inflammatory effects of those compounds were investigated in vitro.
Few-body analogue quantum simulation with Rydberg-dressed atoms in optical lattices
Creators: name: Malz, Daniel
name: Cirac, J. Ignacio
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Most experiments with ultracold atoms in optical lattices have contact interactions, and therefore operate at high densities of around one atom per site to observe the effect of strong interactions. Strong ranged interactions can be generated via Rydberg dressing, which opens the path to explore the physics of few interacting particles. Rather than the unit cells of a crystal, the sites of the optical lattice can now be interpreted as discretized space. This allows studying completely new types of problems in a familiar architecture. We investigate the possibility of realizing problems akin to those found in quantum chemistry, although with a different scaling law in the interactions. Through numerical simulation, we show that simple pseudo-atoms and -molecules could be prepared with high fidelity in state-of-the-art experiments.
description: 7 pages; comments welcome!
Cembranoids from the Vietnamese soft coral Sarcophyton ehrenbergi
Creators: name: Thi, Ngoc Ninh
name: Hong, Hanh Tran Thi
name: Hong, Quang Tran
name: Xuan, Cuong Nguyen
name: Hoai, Nam Nguyen
name: Thao, Do Thi
name: Van Cuong, Pham
name: Cong, Thung Do
name: Van, Kiem Phan
name: Van Minh, Chau
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 60506 Virology
subject: FOS: Biological sciences

description: Using various chromatographic separations, two new cembranoids, ehrenbergols F and G (1 and 2), along with three known analogs ehrenbergol D (3), (+)-isosarcophine (4) and sinulariol Z2 (5) were isolated from the soft coral Sarcophyton ehrenbergi. The structural elucidation was done by extensive analysis of the 1 D and 2 D NMR, HR-ESI-QTOF-MS as well as CD experiments. In addition, compounds 1 (IC50 of 38.38 ± 2.89 µM), 3 (IC50 of 37.14 ± 3.22 µM) and 4 (IC50 of 45.01 ± 2.49 µM) revealed moderate inhibitory activity on LPS-induced NO production in RAW264.7 cells, whereas 2 (IC50 of 73.32 ± 1.95 µM) and 5 (IC50 of 64.48 ± 4.93 µM) exhibited weak effect.
A non-repeating fast radio burst in a dwarf host galaxy
Creators: name: Bhandari, Shivani
name: Gordon, Alexa C.
name: Scott, Danica R.
name: Marnoch, Lachlan
name: Sridhar, Navin
name: Kumar, Pravir
name: James, Clancy W.
name: Qiu, Hao
name: Bannister, Keith W.
name: Deller, Adam T.
name: Eftekhari, Tarraneh
name: Fong, Wen-fai
name: Glowacki, Marcin
name: Prochaska, J. Xavier
name: Ryder, Stuart D.
name: Shannon, Ryan M.
name: Simha, Sunil
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the discovery of as-of-yet non-repeating Fast Radio Burst (FRB), FRB 20210117A, with the Australian Square Kilometer Array Pathfinder (ASKAP) as a part of the Commensal Real-time ASKAP Fast Transients (CRAFT) Survey. The sub-arcsecond localization of the burst led to the identification of its host galaxy at a $z=0.214(1)$. This redshift is much lower than what would be expected for a source dispersion measure (DM) of 729 pc cm$^{-3}$, given typical contributions from the intergalactic medium and the host galaxy. Optical observations reveal the host to be a dwarf galaxy with little on-going star formation, very different to the dwarf host galaxies of known repeating FRBs 20121102A, and 20190520B. We find an excess DM contribution from the host and attribute it to the FRB's local environment. We do not find any radio emission from the FRB site or host galaxy. The low magnetized environment and lack of a persistent radio source (PRS) indicate that the FRB source is older than those found in other dwarf host galaxies, and establish the diversity of FRB sources in dwarf galaxy environments. We find our observations to be fully consistent with the hypernebula model, where the FRB is powered by accretion-jet from a hyper-accreting black hole. Finally, our high-time resolution analysis reveals burst characteristics similar to those seen in repeating FRBs. We encourage follow-up observations of FRB 20210117A to establish any repeating nature.
description: 15 pages, 9 figures, 2 Tables
title: The 13 Key Elements of an Insider Threat Program
Creators: name: Trzeciak, Randall
name: Costa, Daniel
Publisher: name: Software Engineering Institute, Carnegie Mellon University
Year: 2023

description: In the last three years, since the arrival of the COVID-19 pandemic in the United States, the nature of the workplace has changed significantly. As of February 2023, 76 percent of the workforce with a job that can be done from home in the United States was working a hybrid or completely remote schedule, according to Pew Research. Of that number, roughly one-third is completely remote. In this evolving work climate, organizations need to be increasingly vigilant against malicious and unintentional (non-malicious) insider incidents. This post from the Carnegie Mellon University Software Engineering Institute presents the 13 key elements of an insider threat program.
Dry clutch for automated manual transmissions. Structural analysis and control strategies
Creators: name: (:Unkn) Unknown
Publisher: name: Universita degli studi di Salerno
Year: 2014
Subjects: subject: ING-IND/13 MECCANICA APPLICATA ALLE MACCHINE

description: 2012 - 2013
description: The goal of this thesis is the study of the automotive push-type dry clutches used in the Automatic Manual Transmissions (AMTs) and in the Dual Clutch Transmissions (DCTs) in order to improve their performances dur- ing the engagements phases. The push-type clutch is very widespread in the automotive sector because it allows many advantages in terms of cost, relia- bility, isolation of vibrations to the driveline, reduced axial size and stability to the facings wear [1]. Instead, the main advantages of an AMT, respect to the Automatic Transmissions (ATs), are improvements in terms of safety, reliability, and driving performances together with the reduction of the fuel consumption and pollutant emissions [2]. For these reasons by mixing the advantages of the push-type clutch with the advantages of the AMT it is possible to attain very high performance [3, 4]. On the other hand, the most important drawback of the AMT is the power interruption (the so called "torque gap") during the gear shifts events. To solve this problem in the last decade the DCTs have been introduced. In fact, by applying the engine torque to one clutch just as the engine torque is being disconnected from the other one [5] the torque transmission is allowed also during the gear shift phases. In this light, the work developed for this Thesis aimed at providing useful information both to the clutch designers and to control algorithm designers in order to enhance the performances, and consequently, the market di usion mof the AMT and DCT transmissions. The thesis is organized as follows. Chapter 2 is an introductory section on the historical evolution of the clutches and of the automotive transmissions systems. Chapter 3 deals with the transmissibility torque model by consid- ering the main factors which a ect the elastic components of a push-type clutch and the friction coe cient. In the Chapter 4 application of control algorithms both for a two DoFs driveline model and for a ve DoFs model are introduced. Finally, the Chapter 5 underlines the concluding remarks. [edited by Author]
title: Benefits of CEUS in the characterization of focal nodular liver lesions in everyday practice
Creators: name: Sükösd, Hunor
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Metastases
subject: Haemangioma
subject: Education and training
subject: Efficacy studies
subject: Diagnostic procedure
subject: Cost-effectiveness
subject: Ultrasound
subject: MR
subject: CT
subject: Liver
subject: Contrast agents
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The purpose of this article is to emphasize the key features, possibilities, pitfalls and most of all the benefits of Contrast Enhanced Ultrasound (CEUS) in the diagnostics of focal liver lesions. Due to the fact, that ultrasound examination is a...
Study on the chemical composition of Caesalpinia sinensis
Creators: name: Leng, Lu-Fen
name: Lai, Qi
name: Lv, Dian
name: Yin, Jun-Lin
name: Zeng, Guang-Zhi
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry

description: Five compounds were isolated from the methanolic extract of Caesalpinia sinensis stems and leaves including a new cassane-type butenolide norditerpenoid compound (1) and a new type of biphenyl compound (2); the compounds were identified as Norcaesalpin-one (1), 4'-hexyl 3-methyl 6-methoxy-[1,1'-biphenyl]-3,4'-dicarboxylate (2), rhapontigenin (3), 3-deoxysappanchalcone (4), isoliquiritigenin (5). Compounds 1-5 were first isolated from C. sinensis. Their structures were elucidaded on the basis of MS, IR, NMR spectroscopic, X-ray diffraction data analyses. The NGF-induced PC12 differentiation assay was performed on compound 1, and the results showed that compound 1 had a promotive effect on PC12 cell differentiation, with a differentiation rate of 12.32%. In addition, compounds 1-5 were evaluated for their cytotoxic activities against four human cancer cell lines (including A-549, BGC-823, MDA-MB-231, HepG2), and the results showed that compounds 3-5 showed inhibitory activity against these cancer cell lines with IC50 values ranging from 22.96 to 74.92 μmol/L, compound 4 showing the best activity against human malignant melanoma cells A375 with an IC50 value of 22.96 μmol/L.
Gravitational duality, Palatini variation and boundary terms: A synopsis
Creators: name: Lindström, Ulf
name: Sarıoğlu, Özgür
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider $f(R)$ gravity and Born-Infeld-Einstein (BIE) gravity in formulations where the metric and connection are treated independently and integrate out the metric to find the corresponding models solely in terms of the connection, the archetypical treatment being that of Eddington-Schrödinger (ES) duality between cosmological Einstein and Eddington theories. For dimensions $D\ne2$, we find that this requires $f(R)$ to have a specific form which makes the model Weyl invariant, and that its Eddington reduction is then equivalent to that of BIE with certain parameters. For $D=2$ dimensions, where ES duality is not applicable, we find that both models are Weyl invariant and equivalent to a first order formulation of the bosonic string. We also discuss the form of the boundary terms needed for the variational principle to be well defined on manifolds with non-null boundaries. This requires a modification of the Gibbons-Hawking-York (GHY) boundary term for gravity. This modification also means that the dualities between metric and connection formulations are consistent and include the boundary terms.
description: 15 pages, one figure; Ver. 2: 16 pages, one figure, various clarifying remarks added, accepted for publication in CQG
title: Utility of routine lower limb CT angiogram in the preoperative assessment of traumatic knee injuries.
Creators: name: Shekkeris, Andreas
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Musculoskeletal system
subject: Trauma
subject: Vascular
subject: CT-Angiography
subject: Diagnostic procedure
subject: Surgery
subject: Trauma

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Assess the utility of routine preoperative lower limb CT angiography (CTA) for patients with traumatic knee injuries, undergoing surgery and/or ligamentous...
Start 2 Collaborate: Letterenhuis and University of Antwerp Joining Forces in Tackling Challenges Related to Born-Digital Archives
Creators: name: Van Ongeval, Isabelle
name: Bekius, Lamyk
Publisher: name: Zenodo
Year: 2024

description: A lightning talk presented at iPRES 2024 about the potential of genuine collaboration and partnerships between academics and archivists in the scope of born-digital archives.
A Formal Approach to Distributed System Tests Design
Creators: name: Shchurov, Andrey A.
name: Marik, Radek
Publisher: name: arXiv
Year: 2014
Subjects: subject: Software Engineering (cs.SE)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: Deployment of distributed systems sets high requirements for procedures and tools for the complex testing of these systems. This work introduces a formal four-layered model for test generation mission on the basis of the component-based approach and the concept of layered networks. Based on this model, we describe the test generation strategy that covers every interaction from the end-user requirements on all coexisting architectural layers, and checks the internal consistency of the system technical specifications with respect to the end-user requirements. The next step introduces the Prolog-based approach to representing this model and the requirements-coverage strategy
description: 10 pages, 6 figures
title: Dental implants - what the general radiologist needs to know.
Creators: name: Pelta, Michelle
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Prostheses
subject: Outcomes
subject: Artifacts
subject: Technical aspects
subject: MR
subject: Conventional radiography
subject: Cone beam CT
subject: Head and neck

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Purpose: Understand the diagnostic contribution of each of the common imaging modalities of2D panoramic and peri-apical radiography; cone-beam computed tomography (CBCT), multi-detector computed tomography (MDCT) and Magnetic Resonance Imaging...
Magnetic ground state of the Kitaev Na$_2$Co$_2$TeO$_6$ spin liquid candidate
Creators: name: Yao, Weiliang
name: Zhao, Yang
name: Qiu, Yiming
name: Balz, Christian
name: Stewart, J. Ross
name: Lynn, Jeffrey W.
name: Li, Yuan
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: As a candidate Kitaev material, Na$_2$Co$_2$TeO$_6$ exhibits intriguing magnetism on a honeycomb lattice that is believed to be $C_3$-symmetric. Here we report a neutron diffraction study of high quality single crystals under $a$-axis magnetic fields. Our data support the less common notion of a magnetic ground state that corresponds to a triple-$\mathbf{q}$ magnetic structure with $C_3$ symmetry, rather than the multi-domain zigzag structure typically assumed in prototype Kitaev spin liquid candidates. In particular, we find that the field is unable to repopulate the supposed zigzag domains, where the only alternative explanation is that the domains are strongly pinned by hitherto unidentified structural reasons. If the triple-$\mathbf{q}$ structure is correct then this requires reevaluation of many candidate Kitaev materials. We also find that fields beyond about 10 Tesla suppress the long range antiferromagnetic order, allowing new magnetic behavior to emerge different from that expected for a spin liquid.
description: 4 pages, 4 figures, plus Supplemental Material
Gemini spectroscopy of the outer disk star cluster BH176
Creators: name: Sharina, M. E.
name: Donzelli, C. J.
name: Davoust, E.
name: Shimansky, V. V.
name: Charbonnel, C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: BH176 is an old metal-rich star cluster. It is spatially and kinematically consistent with belonging to the Monoceros Ring. It is larger in size and more distant from the Galactic plane than typical open clusters, and it does not belong to the Galactic bulge. Our aim is to determine the origin of this unique object by accurately determining its distance, metallicity, and age. The best way to reach this goal is to combine spectroscopic and photometric methods. We present medium-resolution observations of red clump and red giant branch stars in BH176 obtained with the Gemini South Multi-Object Spectrograph.We derive radial velocities, metallicities, effective temperatures, and surface gravities of the observed stars and use these parameters to distinguish member stars from field objects. We determine the following parameters for BH176: $V_h= 0\pm 15$ km/s, $[Fe/H]=-0.1\pm 0.1$, age $7\pm 0.5$ Gyr, $E(V-I)=0.79\pm 0.03$, distance $ 15.2\pm 0.2$ kpc, $α$-element abundance $[α/Fe] \sim 0.25$ dex (the mean of [Mg/Fe], and [Ca/Fe]). BH176 is a member of old Galactic open clusters that presumably belong to the thick disk. It may have originated as a massive star cluster after the encounter of the forming thin disk with a high-velocity gas cloud or as a satellite dwarf galaxy.
description: 15 pages, 7 fufures, Accepted for publication in Astronomy & Astrophysics
Cell tracking for live-cell microscopy using an activity-prioritized assignment strategy
Creators: name: Ruzaeva, Karina
name: Cohrs, Jan-Christopher
name: Kasahara, Keitaro
name: Kohlheyer, Dietrich
name: Nöh, Katharina
name: Berkels, Benjamin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Cell tracking is an essential tool in live-cell imaging to determine single-cell features, such as division patterns or elongation rates. Unlike in common multiple object tracking, in microbial live-cell experiments cells are growing, moving, and dividing over time, to form cell colonies that are densely packed in mono-layer structures. With increasing cell numbers, following the precise cell-cell associations correctly over many generations becomes more and more challenging, due to the massively increasing number of possible associations. To tackle this challenge, we propose a fast parameter-free cell tracking approach, which consists of activity-prioritized nearest neighbor assignment of growing cells and a combinatorial solver that assigns splitting mother cells to their daughters. As input for the tracking, Omnipose is utilized for instance segmentation. Unlike conventional nearest-neighbor-based tracking approaches, the assignment steps of our proposed method are based on a Gaussian activity-based metric, predicting the cell-specific migration probability, thereby limiting the number of erroneous assignments. In addition to being a building block for cell tracking, the proposed activity map is a standalone tracking-free metric for indicating cell activity. Finally, we perform a quantitative analysis of the tracking accuracy for different frame rates, to inform life scientists about a suitable (in terms of tracking performance) choice of the frame rate for their cultivation experiments, when cell tracks are the desired key outcome.
description: Accepted for publication at the 5th IEEE International Conference on Image Processing Applications and Systems 2022 (IPAS)
α-Pyrone and decalin derivatives from the marine-derived fungus Trichoderma harzianum PSU-MF79
Creators: name: Nuansri, Sucheewin
name: Rukachaisirikul, Vatcharin
name: Rungwirain, Narate
name: Kaewin, Suchada
name: Yimnual, Chantapol
name: Phongpaichit, Souwalak
name: Preedanon, Sita
name: Sakayaroj, Jariya
name: Muanprasat, Chatchai
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Hematology
subject: Plant Biology

description: Two new compounds, one α-pyrone (trichoharzianone) and one decalin (trichoharzianin), along with eight known compounds including three decalins, two δ-lactones, two carboxylic acids and one isochroman were isolated from the marine-derived fungus Trichoderma harzianum PSU-MF79. The structures were determined by spectroscopic methods. The relative configuration of trichoharzianin was assigned based on NOEDIFF data and coupling constants whereas the absolute configurations were established by comparison of electronic circular dichroism data with those of the co-metabolites. Known (-)-massoia lactone exhibited mild antifungal activity against Cryptococcus neoformans ATCC90113 flucytosine-resistant, Candida albicans ATCC90028 and C. albicans NCPF3153 with MIC values of 128, 200 and 200 µg/mL, respectively, and weak cytotoxic activity against HCT-116 and MCF-7 cell lines with the respective IC50 values of 17 and 32 µM. In addition, it was noncytotoxic against noncancerous Vero cells with an IC50 value of >100 µM.
title: Right ventricular involvement in Hypertrophic Cardiomyopathy: role of CMR
Creators: name: Dapoto, Annarita
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Cardiac
subject: MR
subject: Imaging sequences
subject: Hyperplasia / Hypertrophy

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: HCM is a chronic heritable disorder characterized histologically by myocyte disarray and regional or global ‘left’ ventricular hypertrophy (LVH) [1]. The feature of HCM is asymmetric left ventricular hypertrophy, in the absence of other causes...
MS_5-Well-characterized and reproducible nanostructured layered sulfide/carbon composites with optimized properties for their incorporation in energy storage devices including go/no-go criteria for any considered composition
Creators: name: Aina, Sergio
name: M. Pilar Lobera
name: Bernechea, María
Publisher: name: Zenodo
Year: 2022

description: Well-characterized and reproducible nanostructured layered sulfide/carbon composites with optimized properties for their incorporation in energy storage devices including go/no-go criteria for any considered composition
title: Incidence and morphology of coronary artery fistulas in ECG-gated multislice computed tomography (ECG-MSCT)
Creators: name: Skoczyński, Marcin
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Cardiac
subject: Cardiovascular system
subject: CT
subject: Computer Applications-3D
subject: Outcomes analysis

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Coronary artery fistula (CAF) is a rare cardiac anomaly, typically found incidentally, which, however, may lead to ventricular overload, pulmonary hypertension or even ischemic cardiac events [1]. The frequency of its occurrence has been reported to...
Proton-neutron entanglement in the nuclear shell model
Creators: name: Johnson, Calvin W.
name: Gorton, Oliver C.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Nuclear Theory (nucl-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We compute the proton-neutron entanglement entropy in the interacting nuclear shell model for a variety of nuclides and interactions. Some results make intuitive sense, for example that the shell structure, as governed by single-particle and monopole energies, strongly affects the energetically available space and thus the entanglement entropy. We also find a surprising result: that the entanglement entropy at low excitation energy tends to decrease for nuclides when $N \neq Z$. While we provide evidence this arises from the physical nuclear force by contrasting with random two-body interactions which shows no such decrease, the exact mechanism is unclear. Nonetheless, the low entanglement suggests that in models of neutron-rich nuclides, the coupling between protons and neutrons may be less computationally demanding than one might otherwise expect.
description: 13 pages, 5 figures
Investigating the Role of Computing Education for Informed Usage Decision-Making
Creators: name: Gebhardt, Luisa
name: Leinweber, Marc
name: Michaeli, Tilman
Publisher: name: Association for Computing Machinery (ACM)
Year: 2023

description: Every person is confronted with multiple usage decisions, especially in the context of digital systems. The challenge for computing education is to enable students to make these decisions in an “informed” manner, which is considered a key competence needed to become a responsible citizen. As a first step within our research project, we report an attempt, inspired by healthcare research, to measure informed usage decisions by calculating a score indicating the "informedness" of a decision. We evaluate and discuss our method based on a first findings from a field test with 28 students.
Associated Legendre Polynomials and Spherical Harmonics Computation for Chemistry Applications
Creators: name: Limpanuparb, Taweetham
name: Milthorpe, Josh
Publisher: name: arXiv
Year: 2014
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Associated Legendre polynomials and spherical harmonics are central to calculations in many fields of science and mathematics - not only chemistry but computer graphics, magnetic, seismology and geodesy. There are a number of algorithms for these functions published since 1960 but none of them satisfy our requirements. In this paper, we present a comprehensive review of algorithms in the literature and, based on them, propose an efficient and accurate code for quantum chemistry. Our requirements are to efficiently calculate these functions for all non-negative integer degrees and orders up to a given number (<=1000) and the absolute or the relative error of each calculated value should not exceed 10E-10. We achieve this by normalizing the polynomials, employing efficient and stable recurrence relations, and precomputing coefficients. The algorithm presented here is straightforward and may be used in other areas of science.
description: The 40th Congress on Science and Technology of Thailand (STT40)
Cavity-mediated coupling of antiferromagnetic spin waves
Creators: name: Białek, M.
name: Knap, W.
name: Ansermet, J. -Ph.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Coupling of space-separated oscillators is interesting for quantum and communication technologies. In this work, it is shown that two antiferromagnetic oscillators placed inside an electromagnetic cavity couple cooperatively to its terahertz modes and, in effect, hybridized magnon-polariton modes are formed. This is supported by a systematic study of reflection spectra from two parallel-plane slabs of hematite ($α$-Fe$_2$O$_3$), measured as a function of their temperatures and separation distance, and modeled theoretically. The mediating cavity was formed by the crystals themselves and the experiment was performed in a practical distance range of a few millimetres and above room temperature. Cavity-mediated coupling allows for engineering of complex resonators controlled by their geometry and by sharing properties of their components.
title: Thyroid nodule simple hypoechogenicity – is this sign enough to determine malignancy risk?
Creators: name: Rauda, Madara
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Head and neck
subject: Thyroid / Parathyroids
subject: Ultrasound
subject: Biopsy
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The percentage of malignant thyroid nodules have been almost tripled since last century [1, 2] and it had been explained by the increased usage of ultrasound examination. More and more authors are discussing overdiagnosis and overtreatment of...
Software Heritage Save-a-thon : Partager son code c'est bien, l'archiver c'est mieux !
Creators: name: Poulain, Pierre
Publisher: name: Zenodo
Year: 2022
Subjects: Software Heritage
open source

description: Présentation donnée lors de l'atelier Inria Academy du 09/11/2022 lors du salon Open Source Experience (OSXP)
Science–media online training challenges and opportunities
Creators: name: Ponce, Rita
name: Vala, Filipa
name: Costa, Gil
name: Hyldgård, Peter
name: Sá, Sara
name: Pinto, Renata
name: Ferreira, Miguel
name: Ambrósio, Susana
name: Branquinho, Raquel
name: García, Antonio
name: Drobniak, Szymek
Publisher: name: Zenodo
Year: 2022

description: EuroScitizen COST Action is a research network which aims to identify targeted strategies to raise levels of scientific literacy in Europe using evolution as a model. One of the activities developed by the EuroScitizen Media Working Group (WG4) was a set of Training Schools in Science and Media directed to young scientists and journalists. By uniting scientists and journalists, we aimed to promote better communication between the two groups while giving advanced training in science communication. The training activities were originally planned as one in-person Training School but converted to online events due to the COVID-19 pandemic. This required an adjustment of schedule and contents, and instead of having a training school for three full days, as in the planned in-person school, we developed several shorter sessions. Herein, we present the set of Science and Media training events we organised from June 2021 through February 2022, as well as the main challenges we encountered and what we found to be advantages of the online environment for training. We also share a checklist we developed for the organisation of training schools that may provide a useful tool for people planning other training events. Poster presented at EuroScitizen Sustainability meeting, 20-22 June 2022, Aveiro, Portugal