cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Migration of planets in circumbinary discs
Creators: name: Thun, Daniel
name: Kley, Wilhelm
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The discovery of planets in close orbits around binary stars raises questions about their formation. It is believed that these planets formed in the outer regions of the disc and then migrated through planet-disc interaction to their current location. Considering five different systems (Kepler-16, -34, -35, -38 and -413) we model planet migration through the disc, with special focus on the final orbital elements of the planets. We investigate how the final orbital parameters are influenced by the disc and planet masses. Using 2D, locally isothermal, viscous hydrodynamical simulations we first model the disc dynamics for all five systems, followed by a study of the migration properties of embedded planets with different masses. For all systems we find that the discs become eccentric and precess slowly. We confirm the bifurcation feature in the precession period -- gap-size diagram for different binary mass ratios. The Kepler-16, -35, -38 and -413 systems lie on the lower branch and Kepler-34 on the upper one. For systems with small binary eccentricity we find a new non-monotonic, loop-like feature. In all systems the planets migrate to the inner edge of the disc cavity. Depending on the planet-disc mass ratio we observe two different regimes. Massive planets can significantly alter the disc structure by compressing and circularising the inner cavity and they remain on nearly circular orbits. Lower mass planets are strongly influenced by the disc, their eccentricity is exited to high values, and their orbits are aligned with the inner disc in a state of apsidal corotation. In our simulations the final locations of the planets are typically too large with respect to the observations because of the large inner gaps of the discs. The migrating planets in the most eccentric discs (around Kepler-34 and -413) show the largest final eccentricity in agreement with the observations.
description: 19 pages, 19 figures, published in A&A, language edited version
Static and fatigue behaviour of fibre composites infused with rubber- and silica nanoparticle-modified epoxy
Creators: name: Awang Ngah, Shamsiah
Publisher: name: Imperial College London
Year: 2013

description: Delamination has been recognised as the primary defect in composite structures, which can lead to rapid deterioration of the structure. This is because delamination is barely visible damage, and the presence of delamination crack growth between the fibre-matrix layered structure can severely reduce the load bearing capability without being noticed. The present work investigates the matrix toughening approach via the addition of a second phase copolymer and rigid silica nanoparticles in an attempt to enhance the delamination resistance in Glass Fibre (GF) composites. This investigation includes the analysis of the structure/property relationships of toughened epoxy matrices and their corresponding GF composites under quasi-static and fatigue loading conditions. The toughness performance and the toughening mechanisms of the modified epoxies and their corresponding composites are the main theme of this thesis. This investigation revealed a positive correlation between the interlaminar fracture toughness of GF composites and the toughness of the matrix phase. A large toughness increase was observed when using rubber-modified and core-shell rubber (CSR)-modified epoxy matrices. The use of a silica nanoparticle-modified matrix only showed a marginal toughness increase, and in some epoxy systems, the addition of silica nanoparticles was detrimental to the composite toughness. In the hybrid-modified matrix, the largest toughness increase was observed, indicating the presence of a synergistic effect between the rubber particles and silica nanoparticles. The toughening mechanisms in the rubber-modified epoxy were rubber particle cavitation and plastic void growth, whereas in the CSR-modified epoxy the toughening mechanisms were cavitation of the rubbery core and shear deformation in the polymer matrix. In the silica nanoparticle-modified epoxy, debonding of the nanoparticles and subsequent void growth were evident, but the energy dissipation was small and not sufficient to contribute to the large toughness increase. In addition, the silica nanoparticles increased the matrix stiffness and caused the matrix to be less adhered to the fibre surface, thus promoting a fibre-matrix interfacial failure. The fatigue performance of the GF composites with toughened matrices was analysed in terms of fatigue crack growth and fatigue threshold. The addition of rubber particles and silica nanoparticles reduced the fatigue crack growth rate and increased the fatigue threshold values. The fatigue threshold was further increased when using the hybrid-modified matrix suggesting a synergistic toughening effect in the threshold region. Microscopy analysis revealed there were no appreciable difference in the toughening mechanisms between the fatigue and quasi-static fracture behaviour.
Flow Characteristics of Chlamydomonas result in Purely Hydrodynamic Scattering
Creators: name: Mirzakhanloo, Mehdi
name: Alam, Mohammad-Reza
Publisher: name: arXiv
Year: 2018
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: It has long been believed that swimming eukaryotes feel solid boundaries through direct ciliary contact. Specifically, based on observations of behavior of green alga Chlamydomonas reinhardtii it has been reported that it is their "flagella [that] prevent the cell body from touching the surface" [Kantsler et al. PNAS, 2013]. Here, via investigation of a model swimmer whose flow field closely resembles that of C. reinhardtii, we show that the scattering from a wall can be purely hydrodynamic and that no mechanical/flagellar force is needed for sensing and escaping the boundary.
The ecology of marine tidal race environments and the impact of tidal energy development
Creators: name: Broadhurst, Melanie
Publisher: name: Imperial College London
Year: 2012

description: Marine tidal race environments undergo extreme hydrodynamic regimes and are favoured locations for offshore marine renewable tidal energy developments. Few ecological studies have been conducted within these complex environments, and therefore, ecological impacts from tidal energy developments remain unknown. This thesis aimed to investigate the ecological aspects of marine tidal race environments in two themes, using a combination of field-based sampling techniques. I first examined the natural ecological variation of a marine tidal race environment at the spatial and temporal scale. These studies were based on the benthic and intertidal communities within the Alderney Race tidal environment, Alderney. My results suggest that both communities vary in species diversity and composition, at different spatial gradients and timescales. Species showed opportunistic or resilient life history characteristics, highlighting the overall influence of the strong hydrodynamic conditions present. I then explored the ecology of a marine tidal race environment within a renewable tidal energy development site. These studies were based within the European Marine Energy Centre’s tidal energy development site, Orkney. Here, I investigated ecological variation in terms of fish interaction and benthic assemblage structure with a deployed tidal energy device, and, the structure of intertidal communities within the overall development site. Interestingly, my results indicated species-specific interactions with the deployed tidal energy device, which was related to species’ refuge or feeding behaviour. These results also imply that different communities show varied spatial and temporal heterogeneity within a development site, associated with the complex interplay of abiotic and biotic processes. This work begins to reveal the ecological consequences of tidal energy development, with single devices acting as potential short-term artificial reef structures. Further research is recommended within these environments, with reference to how the hydrodynamic regimes directly influence these communities, and, the overall ecological consequences of future large-scale tidal energy development scenarios.
Aranea extensa Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Araneidae
Aranea
Aranea extensa

description: Aranea extensa [spec. nov.]
A. abdomine longo argenteo virescente, pedibus longitudinaliter extensis. Fn. svec. 1216.
Raj. ins. 19. n. 2.
List. aran. f. 3.
Habitat in uliginosis, pedibus ad ramos arcte & longitudinaliter extensis.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 621, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Additional file 5: of High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure
Creators: name: Tyagi, Rajeev
name: Gleeson, Patrick
name: Arnold, Ludovic
name: Tahar, Rachida
name: Prieur, Eric
name: Decosterd, Laurent
name: Jean-Louis PĂŠrignon
name: Olliaro, Piero
name: Druilhe, Pierre
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Number and intensity of artesunate drug pressure cycles required to select for artemisinin resistance using single doses of artesunate. (PDF 97 kb)
Recent Developments in Discrete Torsion
Creators: name: Sharpe, Eric R.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this short note we briefly review some recent developments in understanding discrete torsion. Specifically, we give a short overview of the highlights of a group of recent papers which give the basic understanding of discrete torsion. Briefly, those papers observe that discrete torsion can be completely understood simply as the choice of action of the orbifold group on the B field. We summarize the main points of that work.
description: 12 pages, LaTeX, 2 figures
Additional file 1: of Echinococcus multilocularis inoculation induces NK cell functional decrease through high expression of NKG2A in C57BL/6 mice
Creators: name: Abulizi, Abuduaini
name: Shao, Yingmei
name: Aji, Tuerganaili
name: Li, Zhide
name: Zhang, Chuanshan
name: Aini, Abudusalamu
name: Wang, Hui
name: Tuxun, Tuerhongjiang
name: Li, Liang
name: Zhang, Ning
name: Lin, Renyong
name: Wen, Hao
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology
subject: Computational Biology

description: Table S1. Fluorescent labeled antibodies for flowcytometry. (DOCX 16 kb)
Lensed submillimetre-wave foregrounds and the CMBR
Creators: name: Blain, A. W.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Samples of high-redshift galaxies are easy to select in the millimetre/submillimetre (mm/submm) waveband using sensitive telescopes, because their flux density-redshift relations are expected to be flat, and so the selection function is almost redshift-independent at redshifts greater than 0.5. Source counts are expected to be very steep in the mm/submm waveband, and so the magnification bias due to gravitational lensing is expected to be very large, both for lensing by field galaxies and for lensing by clusters. Recent submm-wave observations of lensed images in clusters have constrained the submm-wave counts directly for the first time. In the next ten years our knowledge of galaxy evolution in this waveband will be greatly enhanced by the commissioning of sensitive new instruments and telescopes, including the CMBR imaging space mission Planck Surveyor. This paper highlights the important features of gravitational lensing in the submm waveband and discusses the excellent prospects for lens searches using these forthcoming facilities.
description: 4 pages, 1 two-panel figure. To appear in proceedings of XXXIIIth Moriond conference `Fundamental parameters in cosmology'
Galaxy Cluster Mass Reconstruction Project - IV. Understanding the effects of imperfect membership on cluster mass estimation
Creators: name: Wojtak, R.
name: Old, L.
name: Mamon, G. A.
name: Pearce, F. R.
name: de Carvalho, R.
name: Sifón, C.
name: Gray, M. E.
name: Skibba, R. A.
name: Croton, D.
name: Bamford, S.
name: Gifford, D.
name: von der Linden, A.
name: Muñoz-Cuartas, J. C.
name: Müller, V.
name: Pearson, R. J.
name: Rozo, E.
name: Rykoff, E.
name: Saro, A.
name: Sepp, T.
name: Tempel, E.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The primary difficulty in measuring dynamical masses of galaxy clusters from galaxy data lies in the separation between true cluster members from interloping galaxies along the line of sight. We study the impact of membership contamination and incompleteness on cluster mass estimates obtained with 25 commonly used techniques applied to nearly 1000 mock clusters. We show that all methods overestimate or underestimate cluster masses when applied to contaminated or incomplete galaxy samples respectively. This appears to be the main source of the intrinsic scatter in the mass scaling relation. Applying corrections based on a prior knowledge of contamination and incompleteness can reduce the scatter to the level of shot noise expected for poorly sampled clusters. We establish an empirical model quantifying the effect of imperfect membership on cluster mass estimation and discuss its universal and method-dependent features. We find that both imperfect membership and the response of the mass estimators depend on cluster mass, effectively causing a flattening of the estimated - true mass relation. Imperfect membership thus alters cluster counts determined from spectroscopic surveys, hence the cosmological parameters that depend on such counts.
description: 18 pages, 11 figures, 3tables; accepted for publication in MNRAS
Applications of nucleic acid aptamers in bioanalysis and targeted delivery
Creators: name: Bandhaya, Achirapa
Publisher: name: Imperial College London
Year: 2012

description: The development of sophisticated analytical platforms for many biological specimens owes its success not only to aptamers’ high affinity and specificity for their targets, but also to their versatility. Functions, such as detection/capturing and signalling, can be built into an aptamer molecule. Despite a significant number of reports describing methods of aptamer-based target detection, not many of them are readily transferred into practical use in laboratories where antibodies remain the preferred affinity molecules. The studies presented herein, initially aimed to investigate the adaptability of aptamers as recognition tool in bioanalysis and targeted delivery, offer insights into the issues involved when optimising an aptamer for such applications. The first two results sections of this thesis focus on the development of protocols for aptamer-based assays to maximise the simplicity and robustness of target detection. A putative RNA aptamer with apparent affinity for a synthetic peptide containing a phosphotyrosine residue was further characterised in order to elucidate the context-dependence of its interaction with the target. Since the aptamer had been selected for an application in phosphoproteomics, techniques commonly used in the field, such as dot-blotting and electrophoretic mobility-shift assay, were explored for their compatibility with the aptamer. Surface plasmon resonance analysis was also used to validate the target binding of this aptamer. In the following chapter, the feasibility of using the selective removal of aptamer by target exposure as a means for detecting the presence of bacteria was investigated. The aptamer in each sample was quantified by capillary gel electrophoresis. An aptamer’s role as targeting molecule is described in the final part of the results section. The AS1411 aptamer with affinity for cell-surface nucleolin was conjugated to gold nanorods to facilitate a selective accumulation of these nanoparticles for photothermal ablation of cancer cells. Challenges associated with each of these techniques and suggestions for possible ways to overcome them are discussed.
Oral history interview with Stella, 1981
Publisher: name: Columbia University
Year: 2020
Subjects: Drug addicts--United States
Imprisonment--United States
Drug abuse--History--20th century.--United States
Heroin abuse--History--20th century.--United States
Drug addicts--Rehabilitation--United States
Methadone maintenance--History--20th century.--United States
Drugs--Prescribing
Prostitution--History--20th century.--United States

description: In this interview, Stella discusses her life in New York City, with a focus on her drug use. She describes living in the Hebrew Orphan Asylum from the age of three to fifteen. She discusses being introduced to marijuana, Tuinals, and heroin at the age of eighteen through her coworkers and clients at the beauty shop where she worked in downtown Manhattan. She explains how she became involved in sex work in order to finance her addiction. She describes using Dilaudid during World War II, when there was a shortage of heroin. She reviews her arrest history, and describes her experience being incarcerated at the Women's House of Detention. She discusses her attempts to detox from drugs at various hospitals throughout her three decade long addiction. Facilities included: Morrisania Hospital, Bellevue Hospital, Lexington Kentucky Hospital, and the Morris J. Bernstein Institute. She explains her struggle with alcoholism and liver disease. She delves into her experience joining the methadone program, and the challenges being a methadone patient has posed to her employment options
Structural behaviour of ionic liquids
Creators: name: Dolan, Andrew
Publisher: name: Imperial College London
Year: 2013

description: The ring flipping behaviour of some pyrrolidinium based ionic liquids has been examined using variable temperature NMR spectroscopy, which allows the calculation of the Gibb's free energy of activation of the ring flip. As it was impossible to examine the neat ionic liquids, the work was carried out in solution. The role of the solvent was investigated and its effect on the ring flip activation energy of N-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide was found to be accurately described by the Kamlet-Taft parameters of the solvent. A range of ionic liquids were examined in dimethylsulfoxide solutions. For a range of N-methylpyrrolidinium ionic liquids there was no correlation found between any property of the system and the ring flip activation energy. For a range of N-alkylpyrrolidinium hydrogensulfate ionic liquids there was a positive correlation between the ring flip activation energy and the free volume of the solution. While the free volume term correlates well, it is believed to be indicative of some underlying entropic effect. A range of 1-alkyl-3-methylimidazolium and 1,3-dialkylimidazolium ionic liquids were examined using small angle X-Ray diffractometry. It was found that 1-alkyl-3- methylimidazolium thiocyanates have a unique pre-peak in their diffraction patterns, the structural origin of this peak is a repeating structure that is about twice the length of the cation. Ionic liquids with other anions reported to date, and those studied here, all have a pre-peak originating from a repeating structure that is about the length of the cation. This strongly suggests 1-alkyl-3-methylimidazolium thiocyanates have a different liquid structure than other ionic liquids. A pre-peak was found in 1-butyl-3-methylimidazolium thiocyanate, which is the first report of a pre-peak in an imidazolium based IL with such a short alkyl chain. It was also found that 1,3-dihexylimidazolium ionic liquids have two peaks in the very small angle regime. It was not possible to precisely determined the structural origin of these peaks, however there are two possible explanations. Either first and second order diffraction peaks of a repeating structure about twice the length of cation are being seen, or there are two different structures being formed in the liquid, one of which repeats on the length scale of one cation, the other of which repeats on the length scale of two cations.
Modelling nasopharyngeal colonisation by Streptococcus pyogenes : Bioluminescence and other longitudinal techniques
Creators: name: Alam, Faraz Mainul
Publisher: name: Imperial College London
Year: 2013

description: Streptococcus pyogenes causes an estimated 616 million pharyngitis cases per year and a variety of invasive diseases such as necrotising fasciitis and toxic shock syndrome. The human nasopharynx is the major reservoir for all S. pyogenes infection, including severe invasive disease. A combination of biophotonic imaging (BPI) and direct nasal sampling techniques were used to longitudinally measure the in vivo carriage of S. pyogenes, looking at the effects of virulence factor expression on carriage and transmission and to enable vaccine evaluation. Direct nasal sampling demonstrated that the two component regulatory system, CovR/S, is required for infection and transmission from the nasopharynx. The fitness cost conferred by covR/S mutation in the nasopharynx may explain why S. pyogenes with altered covR/S have not become prevalent in community infections despite conferring a selective advantage in invasive infection. Bioluminescent S. pyogenes strains expressing the luxABCDE operon demonstrated a growth deficit independent of the target site for integration in vitro that manifested as a fitness cost during infection in vivo. Notwithstanding this, bioluminescence expression permitted longitudinal quantitation of S. pyogenes within the nasopharynx using BPI. Intramuscular vaccination with heat killed streptococci or the streptococcal chemokine protease SpyCEP conferred protection against pharyngeal infection in this model. These longitudinal techniques allow for S. pyogenes to be tracked in the nasopharynx non-invasively, and allow for new insights into the pathogenesis of this disease.
Universality in Random Walk Models with Birth and Death
Creators: name: Bender, Carl M.
name: Boettcher, Stefan
name: Meisinger, Peter N.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Models of random walks are considered in which walkers are born at one location and die at all other locations with uniform death rate. Steady-state distributions of random walkers exhibit dimensionally dependent critical behavior as a function of the birth rate. Exact analytical results for a hyperspherical lattice yield a second-order phase transition with a nontrivial critical exponent for all positive dimensions $D\neq 2,~4$. Numerical studies of hypercubic and fractal lattices indicate that these exact results are universal. Implications for the adsorption transition of polymers at curved interfaces are discussed.
description: 11 pages, revtex, 2 postscript figures
Highly efficient spin current generation by the spin Hall effect in Au$_{1-x}$Pt$_x$
Creators: name: Zhu, Lijun
name: Ralph, Daniel. C.
name: Buhrman, Robert A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report very efficient spin current generation by the spin Hall effect in the alloy Au0.25Pt0.75, which, as determined by two different direct spin-orbit torque measurements, exhibits a giant internal spin Hall ratio of > 0.58 (anti-damping spin-orbit torque efficiency of ~ 0.35 in bilayers with Co), a relatively low resistivity of ~ 83 uOhm cm, an exceptionally large spin Hall conductivity of > 7.0x10^5 ohm^-1 m^-1, and a spin diffusion length of 1.7 nm. This work establishes Au0.25Pt0.75 as a milestone spin current generator that provides greater energy efficiency than that yet obtained with other heavy metals or with the topological insulators Bi2Se3 and (Bi,Se)2Te3. Our findings should advance spin-orbit torque-based fundamental research and benefit the development of new fast, efficient spin-orbit torque-driven magnetic memories, skyrmion and chiral domain wall devices, and microwave and terahertz emitters.
Properization: Constructing Proper Scoring Rules via Bayes Acts
Creators: name: Brehmer, Jonas
name: Gneiting, Tilmann
Publisher: name: arXiv
Year: 2018
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: Scoring rules serve to quantify predictive performance. A scoring rule is proper if truth telling is an optimal strategy in expectation. Subject to customary regularity conditions, every scoring rule can be made proper, by applying a special case of the Bayes act construction studied by Grünwald and Dawid (2004) and Dawid (2007), to which we refer as properization. We discuss examples from the recent literature and apply the construction to create new types, and reinterpret existing forms, of proper scoring rules and consistent scoring functions. In an abstract setting, we formulate sufficient conditions under which Bayes acts exist and scoring rules can be made proper.
Aranea fimbriata Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Araneidae
Aranea
Aranea fimbriata

description: Aranea fimbriata [spec. nov.]
A. abdomine oblongo nigro: linea utrinque laterali alba, pedibus fuscis. Fn. svec. 1226.
Species Aranearum variant aetate saepe & sexu; difficillime perfectae in museis asservantur; plures itaque videndae apud Listerum, Albinum, imprimis vero apud oculatissimum Clerck de Araneis Svecicis. Holm. 1757. quart. qui ultra 60 habet.
Clerck. aran. 102. t. 5. f. 9.
Habitat in Aquis, super aquas currens.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on pages 621-622, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Cosmological predictions from the Misner brane
Creators: name: Gonzalez-Diaz, Pedro F.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Within the spirit of five-dimensional gravity in the Randall-Sundrum scenario, in this paper we consider cosmological and gravitational implications induced by forcing the spacetime metric to satisfy a Misner-like symmetry. We first show that in the resulting Misner-brane framework the Friedmann metric for a radiation dominated flat universe and the Schwarzschild or anti-de Sitter black holes metrics are exact solutions on the branes, but the model cannot accommodate any inflationary solution. The horizon and flatness problems can however be solved in Misner-brane cosmology by causal and noncausal communications through the extra dimension between distant regions which are outside the horizon. Based on a semiclassical approximation to the path-integral approach, we have calculated the quantum state of the Misner-brane universe and the quantum perturbations induced on its metric by brane propagation along the fifth direction. We have then considered testable predictions from our model. These include a scale-invariant spectrum of density perturbations whose amplitude can be naturally accommodated to the required value 10$^{-5}-10^{-6}$, and a power spectrum of CMB anisotropies whose acoustic peaks are at the same sky angles as those predicted by inflationary models, but having much smaller secondary-peak intensities. These predictions seem to be compatible with COBE and recent Boomerang and Maxima measurements
description: 16 pages, RevTex
Additional file 4: of High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure
Creators: name: Tyagi, Rajeev
name: Gleeson, Patrick
name: Arnold, Ludovic
name: Tahar, Rachida
name: Prieur, Eric
name: Decosterd, Laurent
name: Jean-Louis PĂŠrignon
name: Olliaro, Piero
name: Druilhe, Pierre
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Schematic representation of use of drug pressure to select for single-dose resistance in one mouse. (PDF 204 kb)
Oral history interview with Stephen Benedict, 1968
Publisher: name: Columbia University
Year: 2020
Subjects: Presidents--Election--1952.--United States
Campaign speeches

description: 1952 pre-convention campaign for Eisenhower; campaign train; speech writing; transition between administrations, 1952; White House staff and activities. Recollections of Gabriel Hauge, C.D. Jackson, Richard M. Nixon, George Marshall, Joseph McCarthy, Harry Dexter White
On Superpotentials for D-Branes in Gepner Models
Creators: name: Brunner, Ilka
name: Schomerus, Volker
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A large class of D-branes in Calabi-Yau spaces can be constructed at the Gepner points using the techniques of boundary conformal field theory. In this note we develop methods that allow to compute open string amplitudes for such D-branes. In particular, we present explicit formulas for the products of open string vertex operators of untwisted A-type branes. As an application we show that the boundary theories of the quintic associated with the special Lagrangian submanifolds Im ω_i z_i = 0 where ω_i^5=1 possess no continuous moduli.
description: 33 pages, 2 figures
The optical characteristics of the dust of sungrazing comet C/2012 S1 (ISON) observed at large heliocentric distances
Creators: name: Ivanova, Oleksandra
name: Reshetnyk, Volodymyr
name: Skorov, Yury
name: Blum, Jürgen
name: Krišandová, Zuzana Seman
name: Svoreň, Jan
name: Korsun, Pavlo
name: Afanasiev, Viktor
name: Luk'yanyk, Igor
name: Andreev, Maxim
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present an analysis of the photometric and spectroscopic data of the comet C/2012 S1 (ISON) observed at the heliocentric distances of 6.21÷4.81 AU. The photometric observations were made with the 60-cm Zeiss-600 telescope (ICAMER, peak Terskol, Russia) and the spectroscopic observations were performed using the SCORPIO-2 focal reducer mounted in the prime focus of the 6-m BTA telescope (SAO RAS, Russia). We analyse the B, V and R-band images to describe the dusty cometary coma and to investigate its brightness, colours and dust production rate. The spectra cover the wavelength range of 3600÷7070 Å. No emissions which are expected in this wavelength region were detected above the 3$σ$ level. The continuum shows a reddening effect with the normalized gradient of reflectivity along dispersion of (9.3$\pm$1.1)% per 1000 Å. A dust-loss rate was derived using the obtained values and under the different model assumptions. Our simulations clearly indicate that to retrieve dust production from the observational Af$ρ$ parameter is an ambiguous task. The result of such a procedure is strongly dependent on dynamical (e.g. effective density and cross-section) as well as optical (e.g. scattering coefficient and phase function) characteristics of dust grains. A variation of the mentioned parameters can lead to dramatic changes in the evaluation of mass production. We demonstrate that the dynamic and optical properties are interconnected via the microscopic properties of dust grains (effective size and porosity).
Additional file 3: of Occupational, physical, sexual and mental health and violence among migrant and trafficked commercial fishers and seafarers from the Greater Mekong Subregion (GMS): systematic review
Creators: name: Pocock, Nicola
name: Nguyen, Long
name: Lucero-Prisno, Don
name: Zimmerman, Cathy
name: SiĂ˘N Oram
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Cell Biology
Developmental Biology

description: Method of assessing the outcomes. (PDF 98 kb)
title: ADCO, Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Cart. 173 (11 H 939), 226 folios, f. 0152
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0152, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0152, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Lattice fermions with gauge noninvariant measure
Creators: name: Zenkin, Sergei V.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We define Weyl fermions on a finite lattice in such a way that in the path integral the action is gauge invariant but the functional measure is not. Two variants of such a formulation are tested in perturbative calculation of the fermion determinant in chiral Schwinger model. We find that one of these variants ensures restoring the gauge invariance of the nonanomalous part of the determinant in the continuum limit. A `perfect' perturbative regularization of the chiral fermions is briefly discussed.
description: footnotes 2, 7 are extended, two references are added
Additional file 1: of INTEGRA study protocol: primary care intervention in type 2 diabetes patients with poor glycaemic control
Creators: name: Molló, Àngels
name: Berenguera, Anna
name: Rubinat, Esther
name: Vlacho, Bogdan
name: Mata, Manel
name: Franch, Josep
name: Bolíbar, Bonaventura
name: Mauricio, Dídac
Publisher: name: figshare
Year: 2019
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Monitoring plan. The monitoring plan include process for monitoring activities of the study, definition of the key information concerning the realization of the study, the verification of data sources, essential documents of the study. (PDF 294 kb)
ROSAT and Hipparcos Observations of Isolated Pre-Main-Sequence Stars near HD 98800
Creators: name: Jensen, Eric L. N.
name: Cohen, David H.
name: Neuhauser, Ralph
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present new observations of the isolated young stars HD 98800 and CD-33_7795. Pointed ROSAT observations show that their X-ray properties, including X-ray luminosity and variability, are consistent with those of pre-main-sequence (PMS) stars. These observations do not reveal any additional PMS candidates in 40' fields centered on HD 98800 and CD-33_7795. Hipparcos observations of TW Hya (Wichmann et al. 1998) and HD 98800 (Soderblom et al. 1998) show that both stars are roughly 50 pc away and are PMS with ages of ~ 10^7 yr. We searched the Hipparcos catalog (complete down to ~ 2-3 L_sun at this distance) for other PMS stars in the same area. In a 10-pc radius volume of space centered on the previously known PMS stars, we find one additional candidate PMS star (CD-36_7429) with a low space velocity, X-ray emission comparable to that of HD 98800, and Li absorption. There are eight other stars in this area that have dwarf spectral types and lie above the main sequence, but based on their weak X-ray emission, high space velocities, and lack of Li in low-resolution spectra (i.e. EW(Li) < 0.1 Angstroms), these are probably mis-classified subgiants or giants. The current positions and proper motions of TW Hya, HD 98800, and CD-36_7429 are inconsistent with them having formed as a group.
description: Revised version corrects uncertainties of proper motions. See "note added in proof" and revised Figure 3. To appear in the Astronomical Journal, July 1998. LaTeX, uses AASTeX4 macros
Campath induction in renal transplantation
Creators: name: Chan, Ka Kit
Publisher: name: Imperial College London
Year: 2012

description: Kidney transplantation significantly improves quality of life and survival in patients with advanced renal failure and it has become the treatment of choice. Long-term immunosuppressants following transplantation are associated with an increased risk of infection, malignancy and diabetes. Therefore, transplant physicians endeavour to reduce long-term maintenance of the immunosuppression burden and aim to reduce the risk of developing these complications. This has been made possible in the last decade with the introduction of biological induction agents, namely Campath 1H. Campath (Campath-1H) is a humanised rat monoclonal antibody directed against the CD52 antigen, which is one of the most abundant antigens on human lymphocytes. Activation of CD52 antigen causes profound cell lysis and cytokines release. This was thought to be crucial in the mechanism of developing a partial tolerance in transplant recipients. A great interest has developed in its use in transplantation since the first reported use of Campath-1M in solid organ transplantation in the late 1980s and humanised Campath 1H in 1998. Campath had been used as an induction agent together with varying maintenance regimes with different results. In this thesis, I am going to present a brief history of kidney transplantation and a literature review on the use of Campath in transplantation. I will follow by presenting the results and discussions on clinical studies that I developed during my study: the pilot study of Campath induction with tacrolimus monotherapy; CamTac study - a randomised controlled study; the prospective long-term outcomes study; the retrospective cohort dose-finding study; further studies developed to examine the incidence and risk related to long-term immunosuppression – causes of graft loss, long-term allograft pathology, infection, malignancy, haematological profile; and a detailed study on lymphocyte proliferation and rejection following Campath induction.
‘Ich lebe in einem Vexierbild. Ich bilde mich aus und heraus für ein Vexierleben.’—Erich Fried—Jew, humanist, socialist—a study of opposing and complementary aspects of his identity as reflected in his work
Creators: name: Elrick, Manya
Publisher: name: Imperial College London
Year: 2012

description: The following interdisciplinary study focuses on the poetic, prose and translation work of the Austrian Jewish writer Erich Fried. The present research concentrates on expressions of Fried’s identity or his sense of self in his work. Rather than being interpreted as a constant value, identity is perceived as fluid, expressed as a strategic positioning in one’s surroundings. It is postulated that various aspects of Fried’s identity appear in his work. Several traits coalesce to show one aspect or a combination of aspects, presenting an unexpected unity in disparity, as is shown throughout four core chapters. The kaleidoscopic blend of apparent inconsistencies and uncertainties becomes visible in the shape of different faces of Fried which shine through his work. This is indicated in the main proposition: the title of the thesis and the image of the ‘Vexierbild’ draw on Fried’s idea of ‘hidden faces’. The current thesis does not seek the author’s one ‘true face’ which possibly remains hidden under layers of traced and distorted circumlocutory accounts in his work, but rather captures the dynamic which drives the interchange between and metamorphosis of various components which contribute to the framework of Fried’s identity at different times of his life. The complexity of Fried’s identity in exile and its combined evidence in Fried’s literary and translation work is an aspect which has so far not been analysed. The findings reflect the main hypothesis—as suggested by the ‘Vexierbild’ image, aspects of Fried’s identity are complementary and opposing at times, dynamically and productively mirrored in his work.
Study of Higgs Effective Couplings at Electron-Proton Colliders
Creators: name: Hesari, Hoda
name: Khanpour, Hamzeh
name: Najafabadi, Mojtaba Mohammadi
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We perform a search for beyond the standard model dimension-six operators relevant to the Higgs boson at the Large Hadron Electron Collider (LHeC) and the Future Circular Hadron Electron Collider (FCC-he). With a large amount of data (few ab$^{-1}$) and collisions at TeV scale, both LHeC and FCC-he provide excellent opportunities to search for the BSM effects. The study is done through the process $e^-p \to h j ν_e$ where the Higgs boson decays into a pair of $b \bar{b}$ and we consider the main sources of background processes including a realistic simulation of detector effects. For the FCC-he case, in some signal scenarios to obtain an efficient event reconstruction and to have a good background rejection, jet substructure techniques are employed to reconstruct the boosted Higgs boson in the final state. In order to assess the sensitivity to the dimension-six operators, a shape analysis on the differential cross sections is performed. Stringent bounds are found on the Wilson coefficients of dimension-six operators with the integrated luminosities of 1 ab$^{-1}$ and 10 ab$^{-1}$ which in some cases show improvements with respect to the high-luminosity LHC results.
description: 22 pages,7 figures,5 tables
On the Finiteness of the N=4 SUSY Nonlinear Sigma Model in Three Dimensions
Creators: name: Inami, Takeo
name: Saito, Yorinori
name: Yamamoto, Masayoshi
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We construct the {\cal N}=4 supersymmetric nonlinear sigma model in three dimensions which can be expanded in 1/N. We evaluate the effective action at leading order in the 1/N expansion and show the finiteness of the model to this order.
description: 8 pages, minor changes, references added, published version
Higher-order topological insulators protected by inversion and rotoinversion symmetries
Creators: name: van Miert, Guido
name: Ortix, Carmine
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We prove the existence of higher-order topological insulators in: {\it i}) fourfold rotoinversion invariant bulk crystals, and {\it ii}) inversion-symmetric systems with or without an additional three-fold rotation symmetry. These states of matter are characterized by a non-trivial $\mathbb{Z}_2$ topological invariant, which we define in terms of symmetric hybrid Wannier functions of the filled bands, and can be readily calculated from the knowledge of the crystalline symmetry labels of the bulk band structure. The topological invariant determines the generic presence or absence of protected chiral gapless one-dimensional modes localized at the hinges between conventional gapped surfaces.
Monopole Condensation in Lattice SU(2) QCD
Creators: name: Suzuki, Tsuneo
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: This is the short review of Monte-Carlo studies of quark confinement in lattice QCD. After abelian projections both in the maximally abelian and Polyakov gauges, it is seen that the monopole part alone is responsible for confinement. A block spin transformation on the dual lattice suggests that lattice $SU(2)$ QCD is always ( for all $β$) in the monopole condensed phase and so in the confinement phase in the infinite volume limit.
description: Contribution to Confinement '95, March 1995, Osaka, Japan. Names of figure files are corrected. 8 page uuencoded latex file and 10 ps figures
Spatial evolution of optimal disturbances in two fluid boundary layers
Creators: name: Burini, Luca
Publisher: name: Imperial College London
Year: 2013

description: The transition to turbulence of a laminar boundary layer can be affected by free-stream turbulence (FST). High levels of FST can cause the exponentially growing Tollmien-Schlichting wave to be replaced by algebraically growing streaks. Transient growth theory successfully identified counter-rotating, streamwise-oriented vortices as optimal flow configuration for maximum streaks’ amplification. The introduction of a wall film can significantly alter the amplification and evolution of streaks, influencing the penetration of FST inside the boundary layers, and its effects on modal and non-modal stability are yet to be addressed within the appropriate spatially-developing framework. In this work, the outcome of the introduction of a wall film on spatial transient amplification is analysed. Under base flow parallelism, optimal disturbances are computed by solving an optimal evolution problem. This study demonstrates that decreasing the viscosity of the film has a direct impact on the efficacy of the vortex tilting mechanism, leading to transient growth reduction. The different spreading rates of the boundary layer edge and the interface height imply that the effects of stratification vary in the streamwise direction. The assumption of base flow parallelism is therefore relaxed and a framework for the determination of optimal disturbances and spatial transient amplification in two-phase spreading boundary layers is presented, using adjoint optimization techniques. It is shown that spreading effects can alter the prediction of linear stability on streaks amplification. Beyond the early linear stage, the amplitude of the instability waves and interface deformation become appreciable and nonlinear effects cannot be neglected. As a result, an accurate description of the evolution of disturbances in two-fluid boundary layers must account for nonlinear interactions and mean flow distortion. Direct Numerical Simulation (DNS) with interface tracking is used to study the nonlinear evolution of the optimal disturbances in the two-fluid flow.