cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Primordial non-Gaussianity in warm inflation using $δN$ formalism
Creators: name: Zhang, Xiao-Min
name: Ma, Hong-Yang
name: Chu, Peng-Cheng
name: Liu, Jun-Ting
name: Zhu, Jian-Yang
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: A $δN$ formalism is used to study the non-Gaussianity of the primordial curvature perturbation on an uniform density hypersurfaces generated by the warm inflation for the first time. After introducing the framework of the warm inflation and the $δN$ formalism, we obtain an analytic expression for the nonlinear parameter $f_{NL}$ that describes the non-Gaussianity in slow roll approximation, and find that the $δN$ formalism gives a very good result. We analyse the magnitude of $f_{NL}$ and compare our result with those of the standard inflation. Then we discuss two concrete examples: the quartic chaotic model and the hilltop model. The quartic potential model can again be in very good agreement with the Planck results in the warm inflationary scenario, and we give out the concrete results of how the nonlinear parameter depends on the dissipation strength of the warm inflation and the amounts of expansion. We find that the range of the nonlinear parameters in these two cases are both well inside of the allowed region of Planck.
description: 9 pages, 5 figures
On the Principled Description of Human Movements
Creators: name: Hagler, Stuart
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: FOS: Biological sciences

description: While the use of technology to provide accurate and objective measurements of human movement performance is presently an area of great interest, efforts to quantify the performance of movement are hampered by the lack of a principled model that describes how a subject goes about making a movement. We put forward a principled mathematical formalism that describes human movements using an optimal control model in which the subject controls the jerk of the movement. We construct the formalism by assuming that the movement a subject chooses to make is better than the alternatives. We quantify the relative quality of movements mathematically by specifying a cost functional that assigns a numerical value to every possible movement; the subject makes the movement that minimizes the cost functional. We develop the mathematical structure of movements that minimize a cost functional, and observe that this development parallels the development of analytical mechanics from the Principle of Least Action. We derive a constant of the motion for human movements that plays a role that is analogous to the role that the energy plays in classical mechanics. We apply the formalism to the description of two movements: (1) rapid, targeted movements of a computer mouse, and (2) finger-tapping, and show that the constant of the motion that we have derived provides a useful value with which we can characterize the performance of the movements. In the case of rapid, targeted movements of a computer mouse, we show how the model of human movement that we have developed can be made to agree with Fitts' law, and we show how Fitts' law is related to the constant of the motion that we have derived. We finally show that solutions exist within the model of human movements that exhibit an oscillatory character reminiscent of tremor.
description: 117 pages, 16 figures
Supersymmetric Renyi Entropy in $CFT_2$ and $AdS_3$
Creators: name: Giveon, Amit
name: Kutasov, David
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We show that in any two dimensional conformal field theory with (2, 2) supersymmetry one can define a supersymmetric analog of the usual Renyi entropy of a spatial region A. It differs from the Renyi entropy by a universal function (which we compute) of the central charge, Renyi parameter n and the geometric parameters of A. In the limit $n \to1$ it coincides with the entanglement entropy. Thus, it contains the same information as the Renyi entropy but its computation only involves correlation functions of chiral and anti-chiral operators. We also show that this quantity appears naturally in string theory on $AdS_3$.
description: 15 pages; v2: reference added
Push button reproduction attempt of a research claim from Sweeny, K., Rankin, K., Cheng, X., Hou, L., Long, F., Meng, Y., ... & Zhang, W. (2020) in PsyArxiv
Creators: name: Talbert, Eli
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: We selected the claim that because flow states reduce self-awareness and speed the apparent passage of time (i.e., time “flies by”), the authors anticipated that it may be particularly effective for reducing the impact of longer quarantines on well-being. This reflects the following statement from the paper's abstract: "However, flow—but not mindfulness—moderated the link between quarantine length and well-being, such that people who experienced high levels flow showed little or no association between quarantine length and poorer well-being." The authors tested their hypotheses with multiple regression analyses predicting health and well-being from quarantine length, flow, mindfulness, and the interactions between quarantine length and flow/mindfulness. All variables were grand-mean centered. The authors controlled for gender, age, education, region, sibling status, family income, dispositional optimism, intolerance of uncertainty, and satisfaction with life in all analyses. Given the large sample size, the authors define statistical significance for their purposes as effects at p < .01. With the exception of positive emotion and healthy behaviors, flow significantly moderated the relationship between quarantine length and all other measures of well-being. From Table 1, the interaction of Flow x Quarantine Length on “worry”: beta = -0.04, p < 0.01. The focal test in the original paper is: With the exception of positive emotion and healthy behaviors, flow significantly moderated the relationship between quarantine length and all other measures of well-being. From Table 1, the interaction of Flow x Quarantine Length on “worry”: beta = -0.04, p < 0.01.
Study of wavelength dependence of mode instability based on a semi-analytical model
Creators: name: Tao, Rumao
name: Ma, Pengfei
name: Wang, Xiaolin
name: Zhou, Pu
name: Liu, Zejin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We present theoretical study of wavelength dependence of mode instability (MI) in high power fiber lasers, which employs an improved semi-analytical theoretical model. The influence of pump / seed wavelength and photodarkening on threshold has been studied. The results indicate promising MI suppression through pumping or seeding at an appropriate wavelength. Small amounts of photodarkening can lead to significant impact on MI.
description: 6 pages, 5 figures
title: Iowa Byington Reed diary 03, January 1, 1875-December 31, 1877
Creators: name: Reed, Iowa Byington
Publisher: name: University of Iowa. Libraries
Year: 2012
Subjects: subject: FOS: History and archaeology
valueUri: http://www.oecd.org/science/inno/38235147.pdf
subject: FOS: History and archaeology
subject: Domestic life
valueUri: http://id.loc.gov/vocabulary/graphicMaterials/tgm003216

description: Iowa Byington Reed's diaries contain daily entries covering her life from age twenty to just a few weeks before her death at age eighty-four (1872-1936).
Water deuteration and ortho-to-para nuclear spin ratio of H2 in molecular clouds formed via the accumulation of HI gas
Creators: name: Furuya, K.
name: Aikawa, Y.
name: Hincelin, U.
name: Hassel, G. E.
name: Bergin, E. A.
name: Vasyunin, A. I.
name: Herbst, Eric
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We investigate the water deuteration ratio and ortho-to-para nuclear spin ratio of H2 (OPR(H2)) during the formation and early evolution of a molecular cloud, following the scenario that accretion flows sweep and accumulate HI gas to form molecular clouds. We follow the physical evolution of post-shock materials using a one-dimensional shock model, with post-processing gas-ice chemistry simulations. This approach allows us to study the evolution of the OPR(H2) and water deuteration ratio without an arbitrary assumption concerning the initial molecular abundances, including the initial OPR(H2). When the conversion of hydrogen into H2 is almost complete, the OPR(H2) is already much smaller than the statistical value of three due to the spin conversion in the gas phase. As the gas accumulates, the OPR(H2) decreases in a non-equilibrium manner. We find that water ice can be deuterium-poor at the end of its main formation stage in the cloud, compared to water vapor observed in the vicinity of low-mass protostars where water ice is likely sublimated. If this is the case, the enrichment of deuterium in water should mostly occur at somewhat later evolutionary stages of star formation, i.e., cold prestellar/protostellar cores. The main mechanism to suppress water ice deuteration in the cloud is the cycle of photodissociation and reformation of water ice, which efficiently removes deuterium from water ice chemistry. The removal efficiency depends on the main formation pathway of water ice. The OPR(H2) plays a minor role in water ice deuteration at the main formation stage of water ice.
description: Minor changes after language edition, including typo corrections in Eqs. (A.11) and (B.5) (Accepted for publication in A&A)
GRAF1 Regulates MYO6 Dependent Mitochondrial Actin Remodeling
Creators: name: Opheim, Zachary Kyle
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Cardiomyocytes are long lived cells that require a constant supply of ATP generated by mitochondria. Mitochondrial dysfunction results in various diseases, highlighting the importance of mitochondrial quality control. Here we demonstrate that GRAF1 regulates mitochondrial quality via interaction with MYO6, a known regulator of mitophagy. Recent studies revealed MYO6 promotes the formation of actin “cages” around damaged mitochondria in response to stress. We show GRAF1 and MYO6 co-localize to depolarized mitochondria. Additionally, we reveal GRAF1 and MYO6 interact and is dependent upon actin polymerization. Knockdown of GRAF1 results in clustered mitochondrial network morphology following mitochondrial depolarization and subsequent recovery. Furthermore, we observe a lack of MYO6 dissociation from mitochondria following knockdown of GRAF1. In addition, GRAF1 was found to promote mitochondrial function in growth conditions requiring mitochondrial dependent oxidative phosphorylation. Our novel findings suggest that GRAF1 regulates the dissociation of actin cages around damaged mitochondria to promote their eventual degradation.
Radially excited rotating black holes in Einstein-Maxwell-Chern-Simons theory
Creators: name: Blázquez-Salcedo, Jose Luis
name: Kunz, Jutta
name: Navarro-Lérida, Francisco
name: Radu, Eugen
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Rotating black holes in Einstein-Maxwell-Chern-Simons theory possess remarkable features, when the Chern-Simons coupling constant reaches a critical value. Representing single asymptotically flat black holes with horizons of spherical topology, they exhibit non-uniqueness. In particular, there even exist extremal and non-extremal black holes with the same sets of global charges. Both extremal and non-extremal black holes form sequences of radially excited solutions, that can be labeled by the node number of the magnetic gauge potential function. The extremal Reissner-Nordström solution is no longer always located on the boundary of the domain of existence of these black holes, and it neither remains the single extremal solution with vanishing angular momentum. Instead a whole sequence of rotating extremal $J=0$ solutions is present, whose mass converges towards the mass of the Reissner-Nordström solution. These radially excited extremal solutions are all associated with the same near horizon solution. Moreover, there are near horizon solutions that are not realized as global solutions.
description: 24 pages, 28 figures
Compactifications of Deformed Conifolds, Branes and the Geometry of Qubits
Creators: name: Cvetic, M.
name: Gibbons, G. W.
name: Pope, C. N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Differential Geometry (math.DG)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We present three families of exact, cohomogeneity-one Einstein metrics in $(2n+2)$ dimensions, which are generalizations of the Stenzel construction of Ricci-flat metrics to those with a positive cosmological constant. The first family of solutions are Fubini-Study metrics on the complex projective spaces $CP^{n+1}$, written in a Stenzel form, whose principal orbits are the Stiefel manifolds $V_2(R ^{n+2})=SO(n+2)/SO(n)$ divided by $Z_2$. The second family are also Einstein-Kähler metrics, now on the Grassmannian manifolds $G_2(R^{n+3})=SO(n+3)/((SO(n+1)\times SO(2))$, whose principal orbits are the Stiefel manifolds $V_2(R^{n+2})$ (with no $Z_2$ factoring in this case). The third family are Einstein metrics on the product manifolds $S^{n+1}\times S^{n+1}$, and are Kähler only for $n=1$. Some of these metrics are believed to play a role in studies of consistent string theory compactifications and in the context of the AdS/CFT correspondence. We also elaborate on the geometric approach to quantum mechanics based on the Kähler geometry of Fubini-Study metrics on $CP^{n+1}$, and we apply the formalism to study the quantum entanglement of qubits.
description: 31 pages
Push button reproduction attempt of a research claim from Erik Gartzke and Dong-Joon Jo, (2009), in Journal of Conflict Resolution
Creators: name: Tutor, Melba
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: Claim paragraph (from the sourcing sheet): The study's analysis of diplomatic recognition shows that nations with nuclear weapons are more likely to garner attention from other countries (Statement 2). This reflects the following statement from the paper's abstract: "Instrumenting for the decision to proliferate, the authors find that nuclear weapons increase diplomatic status without much affecting whether states fight" (Statement 1). Table 2 presents two regressions that report the effects of nuclear status on the likelihood that State B recognizes State A; the probit model in the first set of columns, with a dichotomous dependent variable, is the model selected. The focal term is Nuclear Weapons A (see Table 2 for details) (Statement 3). Nuclear-capable states are more likely to be recognized by other nations (Coefficient on Nuclear Weapons A term = 0.168 [0.1%]; SE = 0.033) (Statement 4). The focal test in the original paper is: Nuclear-capable states are more likely to be recognized by other nations (Coefficient on Nuclear Weapons A term = 0.168 [0.1%]; SE = 0.033)
Glial Scar Formation-Systematic Review
Creators: name: Manrique-Castano, Daniel
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Life Sciences
subject: Neuroscience and Neurobiology
subject: Astrocyte reactivity
subject: Astrogliosis
subject: Brain injury
subject: Glial Scar

description: A systematic review exploring the mechanisms of astrogliosis and glial scar formation following brain injuries.
Poster Dominican Republic (EMP-LAC 2023). Modeling of alternative scenarios for decarbonization of the energetic sector of the Dominican Republic through OSeMOSYS to 2070.
Creators: name: Mejía, Miguel Euclides Aybar
Publisher: name: Zenodo
Year: 2023
Subjects: OSeMOSYS

description: Poster EMP-LAC2023_poster template_DominicanRepublic
In-medium nucleon-nucleon elastic cross sections determined from nucleon-induced reaction cross sections data
Creators: name: Ou, Li
name: He, Xueying
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Within the framework of the improved quantum molecular dynamics model, the medium modifications on the free nucleon-nucleon elastic cross sections are investigated. By using various in-medium nucleon-nucleon elastic cross sections in the model, the nucleon-induced reactions on various targets are simulated, and the excitation functions of reaction cross sections in the energy range from 25 MeV to 1 GeV are calculated. By comparing the calculations with the experimental data, an isospin, density, and momentum-dependence medium correction factor on free nucleon-nucleon elastic cross sections is determined.
description: 12 pages, 5 figures
Cytokine Detection Technology
Creators: name: West, Dora
Publisher: name: Zenodo
Year: 2023

description: Cytokines are a class of highly active, multifunctional, soluble small-molecule proteins secreted by activated immune cells and certain stromal cells. Cytokines are widely involved in various biological functions such as immune response, cell migration, and signal transduction through paracrine, autocrine, and endocrine approaches. Cytokine assays can assist in determining the immune function of the body and help in research related to the disease mechanism, diagnosis, and treatment. There are various assays for cytokines, and you can choose the most appropriate assay according to sample size, assay needs, and budget.
Bayesian Multiverse - Culture & Work Morality Project
Creators: name: Hoogeveen, Suzanne
name: Haaf, Julia
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: Preregistration for Bayesian multiverse analysis for the 6 key effects in the culture and work morality project
One scute ring per year in Testudo graeca? A novel method to identify ring deposition patterns in tortoises
Creators: name: Rodríguez-Caro, Roberto
name: Graciá, Eva
name: Morais Dos Santos, Renata
name: Anadón, José D.
name: Gimenez, Andrés
Publisher: name: Acta Herpetologica
Year: 2015

description: A reliable estimation of individuals’ age is helpful to conduct demographic studies on wildlife populations. In tortoises, many studies have estimated individuals’ age by counting growth rings on their scutes, assuming one ring per year (1:1 ratio). However, the accuracy of this method is controversial. The ring deposition pattern can vary depending on species, or even populations, and should be studied comprehensively. We studied the ring deposition pattern of Testudo graeca in southeastern Iberian Peninsula, using recaptures of 156 individuals between 2004 and 2010. We used a novel approach to explore the ring deposition pattern and to test possible differences between localities and individuals. Our results revealed that most analysed individuals (57.4%) showed a 1:1 ratio, in which rings were deposited during months of activity (spring to autumn). However, we found a trend to count less rings than years, which underestimated 1 year every 3 or 4 years. No differences in the deposition patterns were found among sites, sizes or sexes because the halt in growth during hibernation equally affects all tortoises in all sites. Our results support that the assumed 1:1 ratio in the assignment of individuals’ age is too simplistic. Since ring deposition patterns are complex, the use of statistical approaches capable of handling deviations from the assumed deposition ratios can help to better depict population age structures.
description: Acta Herpetologica, Vol 10 No 2 (2015)
On the taxonomic status of Liolaemus filiorum Pincheira-Donoso & Ramírez, 2005 (Iguania: Liolaemidae): A response to Pincheira-Donoso
Creators: name: Troncoso-Palacios, Jaime
Publisher: name: Acta Herpetologica
Year: 2015

description: I discuss the arguments put forth recently by Pincheira-Donoso, in which the author attempts to revalidate Liolaemus filiorum Pincheira-Donoso & Ramírez, 2005, a species which I had previously considered a junior synonym of L. puritamensis. The author of this revalidation omitted important information including: 1) the description was published without peer review, 2) one of the two types was deposited in a personal collection, 3) the diagnosis is weak and unclear, 4) the holotype was not explicitly described or illustrated. Additionally, the author did not discuss key aspects of my paper, most particularly, the incorrect designation of the holotype of L. filiorum.
description: Acta Herpetologica, Vol 10 No 2 (2015)
New HI 21-cm absorbers at low and intermediate redshifts
Creators: name: Zwaan, M. A.
name: Liske, J.
name: Péroux, C.
name: Murphy, M. T.
name: Bouché, N.
name: Curran, S. J.
name: Biggs, A. D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the results of a survey for intervening HI 21-cm absorbers at intermediate and low redshift (0180 K. A subset of our systems were also searched for OH absorption, but no detections were made.
description: Accepted for publication in MNRAS, 13 pages with 10 figures
Push button reproduction attempt of a research claim from Teovanovic et al. (2020)
Creators: name: Somo, Angela
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: We selected the claim that stronger beliefs in COVID-19 conspiracy theories would predict greater use of PSPs (pseudoscientific practices). This reflects the following statement from the paper’s abstract: “Conspiratorial beliefs consistently predicted all three outcomes.” The claim was tested by a multiple regression model with PSP use as the outcome variable, and cognitive intuition, susceptibility to type 1 error cognitive biases, overestimation of COVID-19 knowledge, and belief in COVID-19 conspiracy theories as predictor variables. This analysis yielded that those with beliefs in COVID-19 conspiracy theories were more likely to follow pseudoscientific advice. From Table 2 - regression coefficient = 0.24, p < 0.001. The focal test in the original paper is: Those with beliefs in COVID-19 conspiracy theories were more likely to follow pseudoscientific advice. From Table 2 - regression coefficient = 0.24, p < 0.001.
Sex and the interaction with the proteomic signature of depression
Creators: name: Goncalves, Samantha
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: subject: Depression, Mental
subject: Sex differences
subject: Proteomics
subject: Machine learning

description: Differences in the prevalence and burden of depression among women have been extensively documented, proving stable across culture, age, and time. Towards characterizing sexual dimorphism in the proteomics of depression, this investigation evaluated the serum levels of over 7,500 analytes on the SomaLogic SomaScan proteomic assay in 75 moderately to severely depressed patients enriched for endogenomorphic symptoms and 78 healthy controls. Combining differential expression and pathway enrichment analyses, the distribution of sex-dependent protein expression in depressed males and females was compared, and significantly sex-dependent proteins are explored. Differential protein expression results are used to inform the development of classifiers distinguishing between depressed patients and healthy controls. 
An equal number of differentially expressed proteins were found between males and females, with males displaying more proteins with increased expression in cases versus controls and the opposite observed among females. The immune system was the only overrepresented pathway among the proteins with significant sex-dependent expression in depression. Individual examination of immune-identified proteins highlighted multiple proteins not previously associated with depression. Together, these proteins exhibited bidirectional support for alterations of immune and inflammatory protein expression between males and females. Results from classifier development showed that leveraging differentially expressed proteins resulted in improved classifier performance. 
These findings have implications for research on therapeutic targets in depression and classifier development. Future investigations should elaborate on these findings through studies with larger sample sizes of phenotypically diverse cohorts.
Applications of Artificial Intelligence and Machine Learning to Office Laryngoscopy: A Scoping Review
Creators: name: Yao, Peter
name: Rameau, Anaïs
name: German, Alexander
name: Andreadis, Katerina
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Computer Engineering
subject: Medicine and Health Sciences
subject: Medical Specialties
subject: Otolaryngology
subject: Engineering
subject: artificial intelligence
subject: deep learning
subject: laryngoscopy
subject: machine learning

description: A scoping review that aims to answer the question: How has machine learning, deep learning, and artificial intelligence been applied to office laryngoscopy imaging?
title: Towards urban flood susceptibility mapping using data-driven models in Berlin, Germany
Creators: name: Seleem, Omar
name: Ayzel, Georgy
name: Costa Tomaz de Souza, Arthur
name: Bronstert, Axel
name: Heistermann, Maik
Publisher: name: Universitätsverlag Potsdam
Year: 2023
Subjects: subject: 550 Geowissenschaften

description: Identifying urban pluvial flood-prone areas is necessary but the application of two-dimensional hydrodynamic models is limited to small areas. Data-driven models have been showing their ability to map flood susceptibility but their application in urban pluvial flooding is still rare. A flood inventory (4333 flooded locations) and 11 factors which potentially indicate an increased hazard for pluvial flooding were used to implement convolutional neural network (CNN), artificial neural network (ANN), random forest (RF) and support vector machine (SVM) to: (1) Map flood susceptibility in Berlin at 30, 10, 5, and 2 m spatial resolutions. (2) Evaluate the trained models' transferability in space. (3) Estimate the most useful factors for flood susceptibility mapping. The models' performance was validated using the Kappa, and the area under the receiver operating characteristic curve (AUC). The results indicated that all models perform very well (minimum AUC = 0.87 for the testing dataset). The RF models outperformed all other models at all spatial resolutions and the RF model at 2 m spatial resolution was superior for the present flood inventory and predictor variables. The majority of the models had a moderate performance for predictions outside the training area based on Kappa evaluation (minimum AUC = 0.8). Aspect and altitude were the most influencing factors on the image-based and point-based models respectively. Data-driven models can be a reliable tool for urban pluvial flood susceptibility mapping wherever a reliable flood inventory is available.
description: Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe; 1297
Functional analysis of DNA replication initiation
Creators: name: Barbon, Marta
Publisher: name: Imperial College London
Year: 2018

description: Initiation of DNA replication is highly conserved from yeast to human. A crucial factor during this process is the replicative helicase MCM2-7, a ring-shaped hetero-hexameric protein assembly, which unwinds DNA at the replication fork. In a multi-step process, ORC, Cdc6 and Cdt1 promote the loading of two MCM2-7 hexamer into a head-to-head double hexamer around double stranded DNA. The recent cryo-EM structure of an ORC/Cdc6/Cdt1/MCM2-7 (OCCM) intermediate has revealed that the MCM2-7 hexamer and ORC/Cdc6 are connected by C-terminal winged helix domains (WHDs). However, how these WHDs function for helicase loading and MCM2-7 double-hexamer formation has been largely unknown. Using a combination of biochemical and structural approaches, we have investigated the function of the different Mcm C-termini during pre-RC formation. In this study, we developed a new concept, explaining how distinct functions of the individual WHDs drive the multi-step pre-RC formation process. In particular, we discovered that the Mcm5 WHD serves as a key factor in order to signal helicase loading defects and to induce quality control during pre-RC formation. In addition, it was found that the Mcm5 WHD is also required for the OCCM to double hexamer transition. While exploring the Mcm7 WHD, we discovered new rules and requirements for ATP hydrolysis dependent Cdt1 release. Finally, we identified novel mechanism in CDK dependent control of helicase loading, which are important for genome stability. The work performed as part of this thesis has resulted in the discovery of several new mechanisms, which together provide fundamental insights into the function and regulation of the highly complex eukaryotic helicase loading process.
Depictions of Black Love in Ebony Magazine
Creators: name: Odom, Alexandra
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: The ten years between 1979 and 1989 signaled a significant shift in the discourse about the "crisis of the black family", and proposed solutions to this crisis. Public discourse aimed at finding a solution to this “crisis” resulted in wide-ranging criticism of black family dynamics.  Throughout the decade, the increased number of features about dating to marry, maintaining a successful marriage, and advertisements that showcased middle class black family life work to highlight Ebony's message that black romantic love was the key to the success of the black community. Ebony’s emphasis on the importance of black heteronormative romantic love often ignored the larger structural forces that contributed to the famed "crisis". As historians have dedicated increased attention to the study of black marriages and the black family in recent years, studies of popular depictions of black love in print media are a valuable addition to these growing conversations.
Notes on the reproductive ecology of the Oaxaca Mud Turtle (Kinosternon oaxacae) in the vicinity of Mazunte, Mexico
Creators: name: Vázquez Gómez, Alma G.
name: Harfush, Martha
name: Macip-Ríos, Rodrigo
Publisher: name: Acta Herpetologica
Year: 2015

description: Kinosternon oaxacae is one of the least known species of Mexican turtles. We conducted a preliminary survey from August to November 2013 in three localities on the coast of Oaxaca with the objective to increase and complement the knowledge of the reproductive ecology of Kinosternon oaxacae, including field data on nesting season, clutch size, egg size, and relative clutch mass. We found 21 females with eggs in their oviducts. With this sample we determined that the reproductive season extends from early May to early November. Clutch size averaged two eggs (± 1), and egg size averaged 30.61 (± 1.89) mm in length, 17.11 (± 0.69) mm in width, and 7.64 (± 0.57) g in mass. Relative clutch mass (clutch mass/gravid body mass) was 0.046 (± 0.023), and the smallest gravid female was 118.8 mm carapace length. No correlations of reproductive traits were found with body size, and no variation in reproductive traits or body size was detected among localities. Comparisons with related (scorpioides group) species were made.
description: Acta Herpetologica, Vol 10 No 2 (2015)
Living with a chronic illness- adaptation and self-management by adults living with HIV: A scoping review protocol
Creators: name: sematlane, Neo
name: Knight, Lucia
name: Masquillier, Caroline
name: Wouters, Edwin
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Public Health
subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences
subject: Other Social and Behavioral Sciences

description: Scoping Review Protocol
Faster Quantum Walk Search on a Weighted Graph
Creators: name: Wong, Thomas G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A randomly walking quantum particle evolving by Schrödinger's equation searches for a unique marked vertex on the "simplex of complete graphs" in time $Θ(N^{3/4})$. In this paper, we give a weighted version of this graph that preserves vertex-transitivity, and we show that the time to search on it can be reduced to nearly $Θ(\sqrt{N})$. To prove this, we introduce two novel extensions to degenerate perturbation theory: an adjustment that distinguishes the weights of the edges, and a method to determine how precisely the jumping rate of the quantum walk must be chosen.
description: 8 pages, 5 figures
Helminth parasites in the toad Rhinella major (Bufonidae) from Chaco region, Argentina
Creators: name: Hamann, Monika
name: González, Cynthya
Publisher: name: Acta Herpetologica
Year: 2015

description: The present study describes the diversity of helminth parasites of Rhinella major (Anura: Bufonidae) in relation to their body size in 4 subhumid vs. semiarid sampling sites from the Argentine Chaco region. Helminths were found in 81% of the specimens examined (n = 85). Fifteen species (13 in subhumid and 7 in semiarid areas) of helminth parasites were found, and most of them were nematodes. Parasites were found in all the examined organs, with highest prevalence and intensity in the digestive tract. Parasite transmission to the toad host occurs by skin penetration or oral ingestion. Maximum helminth richness ranged between 2 and 4 species per infected toad. The most abundant species was Aplectana hylambatis. Body size of the host was the main factor in determining parasite richness. The helminth parasite fauna was rather different in hosts from subhumid vs. semiarid sites, but the dominant (Aplectana hylambatis) and codominant species (Cylindrotaenia sp. and Rhabdias elegans) were the same. Mean species richness and mean species diversity of helminths were significantly different between the zones. These results suggest that the amount of rainfall and associated humidity affects the distribution and development of the parasite fauna of this toad.
description: Acta Herpetologica, Vol 10 No 2 (2015)
Consumers want NZ farmers to comply with regulations - better monitoring and transparency would help to build trust
Creators: name: Castka, Pavel
name: Ruha, Corey
name: Reid, John
name: Zhao, Xiaoli
Publisher: name: AgResearch
Year: 2024
Subjects: classificationCode: 3506
subject: Marketing
subject: FOS: Economics and business

description: Assurance systems such as freshwater monitoring are a cornerstone of New Zealand's agribusiness. But these systems face growing challenges. Urban communities demand higher transparency and engagement, and consumers are increasingly sceptical of the effectiveness and compliance of farm operations.
Based on a recent survey, we developed a white paper to address these challenges and to improve farm assurance systems. This explores technological developments, public awareness and the potential to incorporate Māori perspectives.
This short article, free to republish under Creative Commons, summarises some of that work.
Nonlinear $q$-voter model with inflexible zealots
Creators: name: Mobilia, Mauro
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Social and Information Networks (cs.SI)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: We study the dynamics of the nonlinear $q$-voter model with inflexible zealots in a finite well-mixed population. In this system, each individual supports one of two parties and is either a susceptible voter or an inflexible zealot. At each time step, a susceptible adopts the opinion of a neighbor if this belongs to a group of $q\geq 2$ neighbors all in the same state, whereas inflexible zealots never change their opinion. In the presence of zealots of both parties the model is characterized by a fluctuating stationary state and, below a zealotry density threshold, the distribution of opinions is bimodal. After a characteristic time, most susceptibles become supporters of the party having more zealots and the opinion distribution is asymmetric. When the number of zealots of both parties is the same, the opinion distribution is symmetric and, in the long run, susceptibles endlessly swing from the state where they all support one party to the opposite state. Above the zealotry density threshold, when there is an unequal number of zealots of each type, the probability distribution is single-peaked and non-Gaussian. These properties are investigated analytically and with stochastic simulations. We also study the mean time to reach a consensus when zealots support only one party.
description: 11 pages, 10 figures. For Physical Review E (accepted, final version)
Predicting dune erosion at dissipative, intermediate, and reflective beaches
Creators: name: Straub, Jessamin Amelia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Coastal communities commonly expend resources on the conservation of dunes to protect infrastructure from storm waves and flooding. Predicting dune erosion is increasingly important as coastal populations increase, sea-level rises, and storms become more powerful. This study configures a storm impact scaling model with oceanographic information from the ADCIRC + SWAN model and frequently-collected beach profiles to predict dune-erosion events at three barrier islands in North Carolina: Core Banks (dissipative), Shackleford Banks (intermediate), and Onslow Beach (reflective). This work emphasizes the importance of constraining beach slope, especially at intermediate and reflective beaches to accurately predict dune erosion. The beach slope of dissipative beaches tends to be stable, while the slope of intermediate and reflective beaches tends to be variable, therefore requiring frequent assessment of beach morphology. This finding is useful for identifying areas requiring more resources for beach surveying to maximize the predictive power of storm impact models.
Positive stereotypes; Pākehā attitudes and Māori men’s experiences
Creators: name: Ruben, Anna-Frances
name: McNamara, Rita
name: Neha, Tia
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Quantitative Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Positive Stereotypes

description: This research explores positive stereotypes about Māori men in New Zealand. Positive stereotypes are beliefs that Māori men have specific skills or advantages based on their ethnic group membership. We are focusing on two in particular that have been discussed in previous literature: that Māori men are natural sportsmen, and that they are practical-minded. The aim of this study is to measure Pākehā endorsement of these two positive stereotypes, and test how these beliefs are associated with advice given to a hypothetical Māori and Pākehā student, i.e. does the advice differ for a Māori and Pākehā male in terms of the domains deemed most important for their future success?
Malformations and body injuries in a hybrid zone of crested newts (Caudata: Salamandridae: Triturus cristatus superspecies)
Creators: name: Mačát, Zdeněk
name: Jeřábková, Lenka
name: Reiter, Antonín
name: Rulík, Martin
name: Jablonski, Daniel
Publisher: name: Acta Herpetologica
Year: 2015

description: Morphological abnormalities occur frequently in wild amphibian populations. We analysed malformation and injuries in the hybrid zone of three crested newt species, in the Czech Republic. In total, 274 individuals from 35 localities in South Moravia (Czech Republic) were examined during the period 2010-2014. Malformations were found in eight newts (2.9%) from seven localities. Injuries were recorded on 59 newts (21.5%). Proportions of tail crest injuries was significantly higher (P ˂ 0.1) in males than in females and the probability of being injured was significantly higher (P ˂ 0.01) for adult individuals. We discuss gene mutation, parasitism and predation as possible explanations for our observations.
description: Acta Herpetologica, Vol 10 No 2 (2015)
Variation of growth rate and survival in embryos and larvae of Rana temporaria populations from the Pyrenees
Creators: name: Oromi, Neus
name: Camarasa, Sebastià
name: Sanuy, Isabel
name: Sanuy, Delfi
Publisher: name: Acta Herpetologica
Year: 2015

description: Variations on embryonic and larval life history traits of ectotherm organisms are strongly affected by temperature conditions. However, these effects can vary between species and populations depending on the mechanisms that act in a determinate local habitat. In the present study, we analysed the effects of temperature on several embryonic and larval traits (survival, development and growth rate until the metamorphosis) of Rana temporaria in two populations living at different altitude (1540 and 2100 m) in the Pyrenees. Five spawns from each population were distributed in a common garden experiment at different temperature treatments according to the normal temperature range that tadpoles might experience in the field and also considering a high treatment (24 °C) to test a possible effect of global warming. Like in other studies of the same species in a latitudinal gradient, the temperature effects depended on the analysed trait. Our results support the general rule that the rate of development is faster at higher temperatures, although survival was significantly affected by the highest temperature in the highland population. Size varied at embryonic and larval stages and was largest at metamorphosis in the highland population. In concordance, the growth rate was higher in the highland population suggesting a countergradient variation in response to the short growing season. However, this possible adaptation can be altered in a global warming scenario with an increase of mortality and limited growth.
description: Acta Herpetologica, Vol 10 No 2 (2015)
A synchronous Gigabit Ethernet protocol stack for high-throughput UDP/IP applications
Creators: name: Födisch, P.
name: Lange, B.
name: Sandmann, J.
name: Büchner, A.
name: Enghardt, W.
name: Kaever, P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: State of the art detector readout electronics require high-throughput data acquisition (DAQ) systems. In many applications, e. g. for medical imaging, the front-end electronics are set up as separate modules in a distributed DAQ. A standardized interface between the modules and a central data unit is essential. The requirements on such an interface are varied, but demand almost always a high throughput of data. Beyond this challenge, a Gigabit Ethernet interface is predestined for the broad requirements of Systems-on-a-Chip (SoC) up to large-scale DAQ systems. We have implemented an embedded protocol stack for a Field Programmable Gate Array (FPGA) capable of high-throughput data transmission and clock synchronization. A versatile stack architecture for the User Datagram Protocol (UDP) and Internet Control Message Protocol (ICMP) over Internet Protocol (IP) such as Address Resolution Protocol (ARP) as well as Precision Time Protocol (PTP) is presented. With a point-to-point connection to a host in a MicroTCA system we achieved the theoretical maximum data throughput limited by UDP both for 1000BASE-T and 1000BASE-KX links. Furthermore, we show that the random jitter of a synchronous clock over a 1000BASE-T link for a PTP application is below 60 ps.
title: Periprocedural anatomical and physiological assessment of myocardial revascularisation
Creators: name: Nozomi, Kotoku
Publisher: name: University of Galway
Year: 2025
Subjects: subject: myocardial revascularisation
subject: Medicine, Nursing andHealth Sciences
subject: Medicine

description: The goal of coronary revascularisation, whether via stenting or bypass grafting, is not merely to address coronary artery obstructions but also to improve clinical outcomes. Functional assessment of coronary stenoses has become the standard of care to evaluate the significance of coronary flow-limitation, and to justify revascularisation in contemporary practice. Imaging- derived physiological assessment based on invasive coronary angiography (ICA) or coronary computed tomographic angiography (CCTA) is an alternative to wire-based pressure measurements, and offers the benefits of being less invasive, more cost-effective, and having a shorter procedure time. In patients with complex coronary artery disease (CAD), the decision by the Heart Team between either percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) is aided using an objective risk model such as the SYNTAX Score Ⅱ 2020, which facilitates an individual assessment of the short- and long-term risk benefit with each treatment modality (1). Optimal medical therapy after revascularisation is associated with long-term survival benefit (2).
Product Space Models of Correlation: Between Noise Stability and Additive Combinatorics
Creators: name: Hązła, Jan
name: Holenstein, Thomas
name: Mossel, Elchanan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Discrete Mathematics (cs.DM)
subject: FOS: Computer and information sciences

description: There is a common theme to some research questions in additive combinatorics and noise stability. Both study the following basic question: Let $\mathcal{P}$ be a probability distribution over a space $Ω^\ell$ with all $\ell$ marginals equal. Let $\underline{X}^{(1)}, \ldots, \underline{X}^{(\ell)}$ where $\underline{X}^{(j)} = (X_1^{(j)}, \ldots, X_n^{(j)})$ be random vectors such that for every coordinate $i \in [n]$ the tuples $(X_i^{(1)}, \ldots, X_i^{(\ell)})$ are i.i.d. according to $\mathcal{P}$. A central question that is addressed in both areas is: - Does there exist a function $c_{\mathcal{P}}()$ independent of $n$ such that for every $f: Ω^n \to [0, 1]$ with $\mathrm{E}[f(X^{(1)})] = μ> 0$: \begin{align*} \mathrm{E} \left[ \prod_{j=1}^\ell f(X^{(j)}) \right] \ge c(μ) > 0 \, ? \end{align*} Instances of this question include the finite field model version of Roth's and Szemerédi's theorems as well as Borell's result about the optimality of noise stability of half-spaces. Our goal in this paper is to interpolate between the noise stability theory and the finite field additive combinatorics theory and address the question above in further generality than considered before. In particular, we settle the question for $\ell = 2$ and when $\ell > 2$ and $\mathcal{P}$ has bounded correlation $ρ(\mathcal{P}) < 1$. Under the same conditions we also characterize the _obstructions_ for similar lower bounds in the case of $\ell$ different functions. Part of the novelty in our proof is the combination of analytic arguments from the theories of influences and hyper-contraction with arguments from additive combinatorics.