cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
PART SELECTION AND MANAGEMENT BASED ON RELIABILITY ASSESSMENT FOR DIE-LEVEL FAILURE MECHANISMS
Creators: name: Sangepu, Lokesh
Publisher: name: Digital Repository at the University of Maryland
Year: 2023
Subjects: subject: Mechanical engineering
subject: FOS: Mechanical engineering

description: Electronic part manufacturers often provide reliability values in metrics such as Mean Time Between Failures (MTBF) and its inverse, Failures in Time (FIT). These metrics assume a constant failure rate and do not account for damage accumulation or wear-out phenomena, making the part selection and management based on this information meaningless.This thesis will report on the challenges associated with manufacturers' avoidance of sharing critical part information and how insufficient information hampers decision-making for part selection. The thesis uses four die-level failure mechanisms (Electromigration, Time-Dependent Dielectric Breakdown, Hot Carrier Injection, and Negative Bias Temperature Instability) as demonstration cases. It investigates the extent to which industry-published documents can be used to obtain the data necessary to simulate these mechanisms. It will report on methods of selecting an appropriate failure model based on the part technology level and identifying the required parameters for estimating the part's time to failure. Various scattered part information sources, literature, and industry-published documents may include the input parameters of failure models. The thesis provides insights into the complexity of understanding these information sources and various methods to obtain the required parameters to estimate the time to failure distributions. The methodology considers the susceptibility of parts to die-level failure mechanisms and compares components for reliability. A simulation template that facilitates practical implementation by enabling designers, engineers, and procurement teams to make informed decisions while selecting electronic parts for specific applications is introduced. The research findings and methodology presented provide valuable insights for users to improve the reliability and performance of electronic systems through effective part selection.
(100988) Mary Lys
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Riemannian optimization for non-centered mixture of scaled Gaussian distributions
Creators: name: Collas, Antoine
name: Breloy, Arnaud
name: Ren, Chengfang
name: Ginolhac, Guillaume
name: Ovarlez, Jean-Philippe
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: This paper studies the statistical model of the non-centered mixture of scaled Gaussian distributions (NC-MSG). Using the Fisher-Rao information geometry associated to this distribution, we derive a Riemannian gradient descent algorithm. This algorithm is leveraged for two minimization problems. The first one is the minimization of a regularized negative log-likelihood (NLL). The latter makes the trade-off between a white Gaussian distribution and the NC-MSG. Conditions on the regularization are given so that the existence of a minimum to this problem is guaranteed without assumptions on the samples. Then, the Kullback-Leibler (KL) divergence between two NC-MSG is derived. This divergence enables us to define a minimization problem to compute centers of mass of several NC-MSGs. The proposed Riemannian gradient descent algorithm is leveraged to solve this second minimization problem. Numerical experiments show the good performance and the speed of the Riemannian gradient descent on the two problems. Finally, a Nearest centroid classifier is implemented leveraging the KL divergence and its associated center of mass. Applied on the large scale dataset Breizhcrops, this classifier shows good accuracies as well as robustness to rigid transformations of the test set.
description: Accepted at IEEE Transactions on Signal Processing
Additional file 4 of International single-step SNPBLUP beef cattle evaluations for Limousin weaning weight
Creators: name: Bonifazi, Renzo
name: Calus, Mario P. L.
name: ten Napel, Jan
name: Veerkamp, Roel F.
name: Michenet, Alexis
name: Savoia, Simone
name: Cromie, Andrew
name: Vandenplas, Jérémie
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 4: Figure S3. Direct and maternal EBV realized Mendelian sampling (RMS) trends in each countrya expressed in genetic standard deviation (GSD) for genotyped and non-genotyped animalsb computed with pedigree-based BLUP international (PBLUPINT) and single-step SNP-BLUP international (ssSNPBLUPINT) models. aCZE Czech Republic, DFS Denmark, Finland and Sweden, IRL Ireland, DEU Germany, CHE Switzerland. bGenotyped animals: animals with genotype that appear in the pseudo-national pedigree (with or without phenotype in the country). Non-genotyped animals: animals that appear in the pseudo-national pedigree without genotype and with phenotype in the country.
Magnetic Effects Promote Supermassive Star Formation in Metal-enriched Atomic-cooling Halos
Creators: name: Hirano, Shingo
name: Machida, Masahiro N.
name: Basu, Shantanu
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Intermediate-mass black holes (with $\geq\!10^5\,M_\odot$) are promising candidates for the origin of supermassive black holes (with $\sim\!10^9\,M_\odot$) in the early universe (redshift $z\sim6$). Chon & Omukai (2020) firstly pointed out the direct collapse black hole (DCBH) formation in metal-enriched atomic-cooling halos (ACHs), which relaxes the DCBH formation criterion. On the other hand, Hirano et al. (2021) showed that the magnetic effects promote the DCBH formation in metal-free ACHs. We perform a set of magnetohydrodynamical simulations to investigate star formation in the magnetized ACHs with metallicities $Z/Z_\odot = 0$, $10^{-5}$, and $10^{-4}$. Our simulations show that the mass accretion rate onto the protostars becomes lower in metal-enriched ACHs than that of metal-free ACHs. However, many protostars form from gravitationally and thermally unstable metal-enriched gas clouds. Under such circumstances, the magnetic field rapidly increases as the magnetic field lines wind up due to the spin of protostars. The region with the amplified magnetic field expands outwards due to the orbital motion of protostars and the rotation of the accreting gas. The amplified magnetic field extracts the angular momentum from the accreting gas, promotes the coalescence of the low-mass protostars, and increases the mass growth rate of the primary protostar. We conclude that the magnetic field amplification is always realized in the metal-enriched ACHs regardless of the initial magnetic field strength, which affects the DCBH formation criterion. In addition, we find a qualitatively different trend from the previous unmagnetized simulations in that the mass growth rate is maximal for the extremely metal-poor ACHs with $Z/Z_\odot = 10^{-5}$.
description: 14 pages, 10 figures, 1 table, Accepted for publication in ApJ
Dynamics of a stochastic ratio-dependent predator-prey model
Creators: name: Linh, Nguyen Thi Hoai
name: Ton, Ta Viet
Publisher: name: arXiv
Year: 2015
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: In this paper, we consider a stochastic ratio-dependent predator-prey model. We firstly prove the existence, uniqueness and positivity of the solutions. Then, the boundedness of moments of population are studied. Finally, we show the upper-growth rates and exponential death rates of population under some conditions.
Experiences of Women of Color with a Nurse Patient Navigation Program for Linkage and Engagement in HIV Care
Creators: name: Ramaiya, Megan
name: Quinlivan, E. Byrd
name: Sullivan, Kristen A.
name: Parnell, Heather
name: Schultz, Katherine
name: Berger, Miriam
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Patient navigation, a patient-centered model of care coordination focused on reducing barriers to care, is an emerging strategy for linking patients to and retaining them in HIV care. The Guide to Healing Program (G2H), implemented at the Infectious Diseases Clinic at UNC Chapel Hill, provided patient navigation to women of color (WOC) new to or re-engaging in HIV care through a ‘nurse guide’ with mental health training and experience. The purpose of this study was to qualitatively explore patients' experiences working with the nurse guide. Twenty-one semi-structured telephone interviews with G2H participants were conducted. Interviews were transcribed and thematic analysis was utilized to identify patterns and themes in the data. Women's experiences with the nurse guide were overwhelmingly positive. They described the nurse guide teaching them critical information and skills, facilitating access to resources, and conveying authentic kindness and concern. The findings suggest that a properly trained nurse in this role can provide critical medical and psychosocial support in order to eliminate barriers to engagement in HIV care, and successfully facilitate patient HIV self-management. The nurse guide model represents a promising approach to patient navigation for WOC living with HIV.
Moments of the negative multinomial distribution
Creators: name: Ouimet, Frédéric
Publisher: name: arXiv
Year: 2022
Subjects: subject: Probability (math.PR)
subject: Statistics Theory (math.ST)
subject: FOS: Mathematics
subject: 62E15, 60E05

description: The negative multinomial distribution appears in many areas of applications such as polarimetric image processing and the analysis of longitudinal count data. In previous studies, Mosimann (1963) derived general formulas for the falling factorial moments of the negative multinomial distribution, while Withers & Nadarajah (2014) obtained expressions for the cumulants. Despite the availability of the moment generating function, no comprehensive formulas for the moments have been calculated thus far. This paper addresses this gap by presenting general formulas for both central and non-central moments of the negative multinomial distribution. These formulas are expressed in terms of binomial coefficients and Stirling numbers of the second kind. Utilizing these formulas, we provide explicit expressions for all central moments up to the 4th order and all non-central moments up to the 8th order.
description: 13 pages, 0 figures
Health Status of HIV-Infected Women Entering Care: Baseline Medical Findings from the Women of Color Initiative
Creators: name: Blank, Arthur E.
name: Quinlivan, E. Byrd
name: Verdecias, Niko
name: Roytburd, Katya
name: Eastwood, Elizabeth A.
name: Fletcher, Jason
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The WOC Initiative is a prospective study of 921 women of color (WOC) entering HIV care at nine (three rural, six urban) sites across the US. A baseline interview was performed that included self-reported limitation(s) in activity, health conditions, and the CDC's health-related quality of life measures (Healthy Days). One-third of the WOC reported limiting an activity because of illness or a health condition and those with an activity limitation reported 13 physically and 14 mentally unhealthy days/month, compared with 5 physically and 9 mentally unhealthy days/month in the absence of an activity limitation. Age was associated with a three- to fourfold increased risk of an activity limitation but only for WOC in the urban sites. Diabetes was associated with a threefold increased risk of a limitation among women at rural sites. Cardiac disease was associated with a six- to sevenfold increased risk of an activity limitation for both urban and rural WOC. HIV+ WOC reported more physically and mentally unhealthy days than the general US female population even without an activity limitation. Prevention and treatment of diabetes and cardiovascular disease will need to be a standard part of HIV care to promote the long-term health and HRQOL for HIV-infected WOC.
title: Changes in NOMI score in repeated angiography are associated with hospital mortality
Creators: name: Stroeder, Jonas
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Small bowel
subject: Catheter arteriography
subject: Diagnostic procedure

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Non occlusive mesenteric ischemia (NOMI) is a severe condition [1] that might occure in a postoperative setting. Clinical signs include distension of the abdomen, abdominal pain as well as rising lactate levels and anuria. NOMI is defined as a...
Medication-Taking Practices of Patients on Antiretroviral HIV Therapy: Control, Power, and Intentionality
Creators: name: Murphy, Joseph S.
name: Maiese, Eric M.
name: Panter, Abigail T.
name: Stein, Kathryn E.
name: Muessig, Kathryn E.
name: Mouw, Mary S.
name: Amola, Kemi
name: Wohl, David A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Among people living with HIV (PLWH), adherence to antiretroviral therapy (ART) is crucial for health, but patients face numerous challenges achieving sustained lifetime adherence. We conducted six focus groups with 56 PLWH regarding ART adherence barriers and collected sociodemographics and ART histories. Participants were recruited through clinics and AIDS service organizations in North Carolina. Dedoose software was used to support thematic analysis. Participants were 59% male, 77% black, aged 23–67 years, and living with HIV 4–20 years. Discussions reflected the fluid, complex nature of ART adherence. Maintaining adherence required participants to indefinitely assert consistent control across multiple areas including: their HIV disease, their own bodies, health care providers, and social systems (e.g., criminal justice, hospitals, drug assistance programs). Participants described limited control over treatment options, ART's impact on their body, and inconsistent access to ART and subsequent inability to take ART as prescribed. When participants felt they had more decision-making power, intentionally choosing whether and how to take ART was not exclusively a decision about best treating HIV. Instead, through these decisions, participants tried to regain some amount of power and control in their lives. Supportive provider relationships assuaged these struggles, while perceived side-effects and multiple co-morbidities further complicated adherence. Adherence interventions need to better convey adherence as a continuous, changing process, not a fixed state. A perspective shift among care providers could also help address negative consequences of the perceived power struggles and pressures that may drive patients to exert control via intentional medication taking practices.
The Reparations Won Curriculum: Examining Dignity Restoration through Education
Creators: name: Zheng, Lily
Publisher: name: University of Chicago
Year: 2022

description: The Reparations Won curriculum operates within a larger quest for justice and reparations for survivors of Chicago police torture in the 1970s to the 1990s. Little, however, is known about how Reparations Won works in the context of Chicago Public Schools and the Chicago policy landscape; moreover, little is known about how the curriculum interacts with the goals of forward-looking reparations and healing for torture survivors. In this paper, I explore how the participation of impacted survivors of Chicago police torture impacts the curriculum and how it is experienced by survivors and students. Using qualitative interviews with various stakeholders in the curriculum and a qualitative analysis of the curriculum, I find that survivors have a tenuous and conditional relationship to the creation and implementation process of the curriculum; as a result, the curriculum has the potential to and does, for at least some survivors, afford the promises of dignity restoration and reparations, leading to healing, hope, and enhanced understanding. I recommend that survivors’ role in Reparations Won be solidified and better supported by Chicago Public Schools and collaborating organizations. This study has implications for reparations policy and social movements as they wrestle with the role of impacted individuals and communities.
On a Particular Thin-shell Wormhole
Creators: name: Övgün, A.
name: Sakalli, I.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, using a black hole with scalar hair, we construct a scalar thin-shell wormhole (TSW) in 2+1 dimensions by applying the Visser's famous cut and paste technique. The surface stress, which is concentrated at the wormhole throat is determined by using the Darmois-Israel formalism. By employing the various gas models, we study the stability analysis of the TSW. The region of stability is changed by tuning the parameters of "l" and "u". It is observed that the obtained particular TSW originated from the black hole with scalar hair could be more stable with particular $l$ parameter, however it still needs exotic matter.
description: 9 pages, accepted for publication in TMPh (Theoretical and Mathematical Physics)
Fault Detection and Emergency Path Planning for Fixed Wing UAVs
Creators: name: Gomez Quezada, Ruth
Publisher: name: Digital Repository at the University of Maryland
Year: 2023
Subjects: subject: Aerospace engineering
subject: Mechanical engineering
subject: FOS: Mechanical engineering
subject: Emergency Path Planning
subject: Fault Detection
subject: Fixed Wing
subject: UAVs

description: The implementation of Uncrewed Aerial Vehicles (UAVs) for civilian and military purposes requires safety protocols. Control surface failures are among the most common issues in fixed-wing UAVs. This study presents two heuristic-based algorithms developed to detect such faults. The Mahalanobis Distance Fault Detection Algorithm (MDFDA) employs the Mahalanobis distance to identify anomalies in UAV states. On the other hand, the Fuzzy Logic Fault Detection Algorithm (FLFDA) uses fuzzy logic to identify jammed control surfaces. In the event of a fault, an emergency path planning algorithm is initiated. This algorithm leverages terrain and population data to pinpoint safe landing zones. However, the type of fault the system encounters will impact the aircraft’s ability to reach these safe zones. In this study, unreachable zones are delineated based on the specific control surface fault detected. These zones are areas where the aircraft cannot land or traverse due to the fault. By employing the proposed protocol, the aircraft can detect a fault during mid-flight, select a safe landing zone within its reachable range, and mitigate the effects of the control surface fault. This approach enhances the chances of preserving the aircraft and ensures the safety of the surrounding population.
title: The efficacy of adaptive atatistical iterative reconstruction-V (ASiR-V) on 70kVp image quality using a new generation wide-detector revolution CT: a phantom study
Creators: name: Chuo, Chiung-Chen
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Radiation physics
subject: CT-Quantitative
subject: Technology assessment

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The latest reconstruction algorithmof low-dose CT imaging is ASiR-V. ASIR-V differs from the earlier Veo CT model-based iterative reconstruction, in that it de-emphasizes the system optics modeling, enabling reconstruction speed similar to...
(100985) Edward Fox Jennings
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Psychosocial Influences on Engagement in Care Among HIV-Positive Young Black Gay/Bisexual and Other Men Who Have Sex with Men
Creators: name: Hussen, Sophia A.
name: Bauermeister, Jose A.
name: Harper, Gary W.
name: Hightow-Weidman, Lisa B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Young black gay/bisexual and other men who have sex with men (YB-GBMSM) living with HIV are at risk for poor engagement in HIV care. Relatively little is known about factors that impact engagement outcomes at various stages along the HIV care continuum in this specific population. The purpose of this analysis was to examine associations between various psychosocial factors and likelihood of engagement at each stage of the care continuum, among a geographically diverse sample of 132 YB-GBMSM living with HIV. Negative self-image, a component of HIV stigma, had an inverse association with early care seeking after HIV diagnosis (OR=1.05; 95% CI 1.01–1.10). Negative self-image was also inversely associated with adherence to medical appointments (OR=0.95; 95% CI 0.91–0.99), while employment (OR=0.30; 95% CI 0.12–0.75) and ethnic identity affirmation (OR=0.28; 95% CI 0.12–0.68) were both positively associated with appointment adherence. HIV-positive identity salience was associated with a higher likelihood of being on antiretroviral therapy (OR=1.06; 95% CI 1.02, 1.09). These findings highlight the importance of processes related to identity development, as both barriers and facilitators of engagement in care for HIV-positive YB-GBMSM.
title: Optimisation of the Philips AlluraXper FD20 imaging setting allows to halve the radiation and contrast-medium doses during lower limb revascularisation procedures
Creators: name: Gentile, Francesco
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Radioprotection / Radiation dose
subject: Interventional vascular
subject: Extremities
subject: Catheter arteriography
subject: Fluoroscopy
subject: Percutaneous
subject: Radiation safety
subject: Angioplasty
subject: Dosimetry
subject: Education and training
subject: Dosimetric comparison

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Percutaneous endovascular revascularization is emerging as preferred treatment in symptomatic peripheral arterial disease (1). These procedures expose patients to significant doses of ionizing radiation, with a potential risk of radiation-induced...
(100987) Hugh Maximilian Elliot
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Stakeholder Engagement in HIV Cure Research: Lessons Learned from Other HIV Interventions and the Way Forward
Creators: name: Excler, Jean Louis
name: Chu, Carissa
name: Ananworanich, Jintanat
name: Lo, Ying Ru
name: Tucker, Joseph D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Clinical and basic science advances have raised considerable hope for achieving an HIV cure by accelerating research. This research is dominated primarily by issues about the nature and design of current and future clinical trials. Stakeholder engagement for HIV cure remains in its early stages. Our analysis examines timing and mechanisms of historical stakeholder engagement in other HIV research areas for HIV-uninfected individuals [vaccine development and pre-exposure prophylaxis (PrEP)], and HIV-infected individuals (treatment as prevention, prevention of mother-to-child transmission, and treatment of acute HIV infection) and articulate a plan for HIV cure stakeholder engagement. The experience from HIV vaccine development shows that early engagement of stakeholders helped manage expectations, mitigating the failure of several vaccine trials, while paving the way for subsequent trials. The relatively late engagement of HIV stakeholders in PrEP research may partly explain some of the implementation challenges. The treatment-related stakeholder engagement was strong and community-led from the onset and helped translation from research to implementation. We outline five steps to initiate and sustain stakeholder engagement in HIV cure research and conclude that stakeholder engagement represents a key investment in which stakeholders mutually agree to share knowledge, benefits, and risk of failure. Effective stakeholder engagement prevents misconceptions. As HIV cure research advances from early trials involving subjects with generally favorable prognosis to studies involving greater risk and uncertainty, success may depend on early and deliberate engagement of stakeholders.
Transverse momentum broadening from NLL BFKL to all orders in pQCD
Creators: name: Caucal, Paul
name: Mehtar-Tani, Yacine
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study, to all orders in perturbative QCD, the universal behavior of the saturation momentum $Q_s(L)$ controlling the transverse momentum distribution of a fast parton propagating through a dense QCD medium with large size $L$. Due to the double logarithmic nature of the quantum evolution of the saturation momentum, its large $L$ asymptotics is obtained by slightly departing from the double logarithmic limit of either next-to-leading log (NLL) BFKL or leading order DGLAP evolution equations. At fixed coupling, or in conformal $\mathcal{N}=4$ SYM theory, we derive the large $L$ expansion of $Q_s(L)$ up to order $α_s^{3/2}$. In QCD with massless quarks, where conformal symmetry is broken by the running of the strong coupling constant, the one-loop QCD $β$-function fully accounts for the universal terms in the $Q_s(L)$ expansion. Therefore, the universal coefficients of this series are known exactly to all orders in $α_s$.
description: 13 pages, 4 figures, 3 appendices
A proof of the refined Gan--Gross--Prasad conjecture for non-endoscopic Yoshida lifts
Creators: name: Corbett, Andrew
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: We prove a precise formula relating the Bessel period of certain automorphic forms on ${\rm GSp}_{4}(\mathbb{A}_{F})$ to a central $L$-value. This is a special case of the refined Gan--Gross--Prasad conjecture for the groups $({\rm SO}_{5},{\rm SO}_{2})$ as set out by Ichino--Ikeda and Liu. This conjecture is deep and hard to prove in full generality; in this paper we succeed in proving the conjecture for forms lifted, via automorphic induction, from ${\rm GL}_{2}(\mathbb{A}_{E})$ where $E$ is a quadratic extension of $F$. The case where $E=F\times F$ has been previously dealt with by Liu.
description: 38 pages in Forum Mathematicum (2016)
Substance Abuse, Violence, and HIV/AIDS (SAVA) Syndemic Effects on Viral Suppression Among HIV Positive Women of Color
Creators: name: Messer, Lynne C.
name: Quinlivan, E. Byrd
name: Sullivan, Kristen A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The combined epidemics of substance abuse, violence, and HIV/AIDS, known as the SAVA syndemic, contribute to the disproportionate burden of disease among people of color in the US. To examine the association between HIV viral load suppression and SAVA syndemic variables, we used baseline data from 563 HIV+ women of color treated at nine HIV medical and ancillary care sites participating in HRSA's Special Project of National Significance Women of Color (WOC) Initiative. Just under half the women (n=260) were virally suppressed. Five psychosocial factors contributing to the SAVA syndemic were examined in this study: substance abuse, binge drinking, intimate partner violence, poor mental health, and sexual risk taking. Associations among the psychosocial factors were assessed and clustering confirmed. A SAVA score was created by summing the dichotomous (present/absent) psychosocial measures. Using generalized estimating equation (GEE) models to account for site-level clustering and individual-covariates, a higher SAVA score (0 to 5) was associated with reduced viral suppression; OR (adjusted)=0.81, 95% CI: 0.66, 0.99. The syndemic approach represents a viable framework for understanding viral suppression among HIV positive WOC, and suggests the need for comprehensive interventions that address the social/environmental contexts of patients' lives.
Blow-up and instability of standing waves for the NLS with a point interaction in dimension two
Creators: name: Finco, D.
name: Noja, D.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 35J10, 35Q55, 35A21

description: In the present note we study the NLS equation in dimension two with a point interaction and in the supercritical regime, showing two results. After obtaining the (nonstandard) virial formula, we exhibit a set of initial data that blow-up. Moreover we show the standing waves $e^{iωt} φ_ω$ corresponding to ground states $φ_ω$ of the action are strongly unstable, at least for sufficiently high $ω$.
description: 12 pages, minor modifications
title: Is contrast media useful for index lesion MR detection in prostate cancer? Biparametric vs multiparametric MR protocol evaluted by radiology residents
Creators: name: Gentile, Francesco
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Genital / Reproductive system male
subject: Oncology
subject: Pelvis
subject: MR-Diffusion/Perfusion
subject: MR
subject: Diagnostic procedure
subject: Computer Applications-Detection, diagnosis
subject: Biopsy
subject: Neoplasia
subject: Education and training
subject: Pathology

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Index lesions have an important role in characterising prostate cancer severity, but there is uncertainty regarding diagnostic value of perfusional sequence (DCE-MRI) in addition to T2WI and DWI. We compared the performance of biparametric...
CD4 + T-Cell Decline after the Interruption of Antiretroviral Therapy in ACTG A5170 Is Predicted by Differential Expression of Genes in the Ras Signaling Pathway
Creators: name: Margolis, David M.
name: Su, Zhaohui
name: Nau, Martin E.
name: Wang, Zhining
name: Skiest, Daniel J.
name: Vahey, Maryanne T.
name: Krambrink, Amy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Patterns of expressed genes examined in cryopreserved peripheral blood mononuclear cells (PBMCs) of seropositive persons electing to stop antiretroviral therapy in the AIDS Clinical Trials Group Study A5170 were scrutinized to identify markers capable of predicting the likelihood of CD4+ T-cell depletion after cessation of antiretroviral therapy (ART). A5170 was a multicenter, 96-week, prospective study of HIV-infected patients with immunological preservation on ART who elected to interrupt therapy. Study entry required that the CD4 count was greater than 350 cells/mm3 within 6 months of ART initiation. Median nadir CD4 count of enrollees was 436 cells/mm3. Two cohorts, matched for clinical characteristics, were selected from A5170. Twenty-four patients with an absolute CD4 cell decline of less that 20% at week 24 (good outcome group) and 24 with a CD4 cell decline of >20% (poor outcome group) were studied. The good outcome group had a decline in CD4+ T-cell count that was 50% less than the poor outcome group. Significance analysis of microarrays identified differential gene expression (DE) in the two groups in data obtained from Affymetrix Human FOCUS GeneChips. DE was significantly higher in the poor outcome group than in the good outcome group. Prediction analysis of microarrays (PAM-R) identified genes that classified persons as to progression with greater than 80% accuracy at therapy interruption (TI) as well as at 24 weeks after TI. Gene set enrichment analysis (GSEA) identified a set of genes in the Ras signaling pathway, associated with the downregulation of apoptosis, as significantly upregulated in the good outcome group at cessation of ART. These observations identify specific host cell processes associated with differential outcome in this cohort after TI.
High-resolution Observations of a Flux Rope with the Interface Region Imaging Spectrograph
Creators: name: Li, Ting
name: Zhang, Jun
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report the observations of a flux rope at transition region temperatures with the \emph{Interface Region Imaging Spectrograph} (IRIS) on 30 August 2014. Initially, magnetic flux cancellation constantly took place and a filament was activated. Then the bright material from the filament moved southward and tracked out several fine structures. These fine structures were twisted and tangled with each other, and appeared as a small flux rope at 1330 Å, with a total twist of about 4$π$. Afterwards, the flux rope underwent a counter-clockwise (viewed top-down) unwinding motion around its axis. Spectral observations of C {\sc ii} 1335.71 Å at the southern leg of the flux rope showed that Doppler redshifts of 6$-$24 km s$^{-1}$ appeared at the western side of the axis, which is consistent with the counter-clockwise rotation motion. We suggest that the magnetic flux cancellation initiates reconnection and some activation of the flux rope. The stored twist and magnetic helicity of the flux rope are transported into the upper atmosphere by the unwinding motion in the late stage. The small-scale flux rope (width of 8.3$^{\prime\prime}$) had a cylindrical shape with helical field lines, similar to the morphology of the large-scale CME core (width of 1.54 $R_{\odot}$) on 2 June 1998. This similarity shows the presence of flux ropes of different scales on the Sun.
description: 15 pages, 7 figures, Solar Physics, in press
ASSESSING THE SUSCEPTIBILITY TO RNA INTERFERENCE OF THE MILKWEED BUG, ONCOPELTUS FASCIATUS (HEMIPTERA)
Creators: name: Argaez, Ebony Michelle
Publisher: name: Digital Repository at the University of Maryland
Year: 2023
Subjects: subject: Entomology
subject: developmental genes
subject: dsRNA
subject: Oncopeltus
subject: RNA Interference

description: RNA interference (RNAi) is an effective method to knock down gene expression in insects and other organisms. It has been adopted for basic research, to elucidate gene function, and applied research, to control insect pests. Here, I examined parameters needed for effective RNAi in the milkweed bug, Oncopeltus fasciatus, an emerging insect model species. For two developmental genes, Sex combs reduced, and even-skipped, very small amounts of dsRNA trigger a robust parental RNAi response. The higher the dose of dsRNA applied, the longer the duration of embryos laid with defects. Testing length-dependence, effectiveness decreased with dsRNAs in the 150 bp to 75 bp range. These developmental genes resulted in subtle, gene-specific defects which provided a more sensitive assay than lethality. Finally, effects of RNAi were transmitted across generations through trophic interactions, the first such discovery to our knowledge. This suggests potential unanticipated environmental risk to non-target insects from RNAi-based insecticides.
title: Does perinephric fat surface density (PnFSD) significantly predict surgical complexity and perioperative outcomes of robot-assisted partial nephrectomy (RAPN)?
Creators: name: Lucarini, Silvia
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Abdomen
subject: Kidney
subject: CT
subject: Surgery

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: In the last years the increasing incidence of detection of small renal masses [1] has generated the need for new evaluation systems that comprehend not only lesion related parameters, but also patient specific factors that may influence surgical...
Additional file 4 of Hunting of hunted: an ensemble modeling approach to evaluate suitable habitats for caracals in India
Creators: name: Jangid, Ashish Kumar
name: Singh, Chandra Prakash
name: Parihar, Jai Singh
name: Chauhan, Jasbir Singh
name: Singh, Rajnish Kumar
name: Verma, Prakash Kumar
name: Singh, Amritanshu
name: Sharma, Shantanu
name: Kolipaka, Shekhar
Publisher: name: figshare
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Additional file 4: Table S1. Details of predictor and correcting variables used for modeling the habitat suitability for caracals in study area. Table S2. District-wise details on gradient of available suitable habitats for caracals in study area.
Genotypic Susceptibility Scores and HIV Type 1 RNA Responses in Treatment-Experienced Subjects with HIV Type 1 Infection
Creators: name: Journigan, Terri
name: Gulick, Roy M.
name: Jiang, Hongyu
name: Katzenstein, David
name: Haubrich, Richard
name: Anderson, Jeffrey A.
name: Swanstrom, Ronald
name: Petch, Leslie
name: Ding, Xiao
name: Fiscus, Susan A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: This study compared the role of genotypic susceptibility scores (GSS) as a predictor of virologic response in a group (n = 234) of HIV-infected, protease inhibitor (PI)-experienced subjects. Two scoring methods [discrete genotypic susceptibility score (dGSS) and continuous genotypic susceptibility score (cGSS)] were developed. Each drug in the subject's regimen was given a binary susceptibility score using Stanford inferred drug resistance scores to calculate the dGSS. In contrast to the dGSS, the cGSS model was designed to reflect partial susceptibility to a drug. Both GSS were independent predictors of week 16 virologic response. We also compared the GSS to a phenotypic susceptibility score (PSS) model on a subset of subjects that had both GSS and PSS performed, and found that both models were predictive of virologic response. Genotypic analyses at enrollment showed that subjects who were virologic nonresponders at week 16 revealed enrichment of several mutated codons associated with nucleoside reverse transcriptase inhibitors (NRTI) (codons 67, 69, 70, 118, 215, and 219) or PI resistance (codons 10, 24, 71, 73, and 88) compared to subjects who were virologic responders. Regression analyses revealed that protease mutations at codons 24 and 90 were most predictive of poor virologic response, whereas mutations at 82 were associated with enhanced virologic response. Certain NNRTI-associated mutations, such as K103N, were rapidly selected in the absence of NRTIs. These data indicate that GSS may be a useful tool in selecting drug regimens in HIV-1-infected subjects to maximize virologic response and improve treatment outcomes.
title: Parameters optimisation and clinical experience in 1H MRS of spinal cord
Creators: name: Hebda, Anna
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Oncology
subject: CNS
subject: Neuroradiology spine
subject: MR-Spectroscopy
subject: Imaging sequences
subject: Technical aspects

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: 1H MRS of spinal cord parameters optimization and its implementation into clinical practice. Obtaining good quality spectra in spinal cord is much more difficult than in brain because of cerebrospinal fluid flow, heartbeat, respiratory...
Plastic damping of Alfvén waves in magnetar flares and delayed afterglow emission
Creators: name: Li, Xinyu
name: Beloborodov, Andrei M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Magnetar flares generate Alfvén waves bouncing in the closed magnetosphere with energy up to $\sim 10^{46}$ erg. We show that on a 10-ms timescale the waves are transmitted into the star and form a compressed packet of high energy density. This packet strongly shears the stellar crust and initiates a plastic flow, heating the crust and melting it hundreds of meters below the surface. A fraction of the deposited plastic heat is eventually conducted to the stellar surface, contributing to the surface afterglow months to years after the flare. A large fraction of heat is lost to neutrino emission or conducted into the core of the neutron star.
description: 10 pages, 12 figures, submitted to ApJ
title: The effectiveness of radiofrequency denervation for treatment of chronic low back pain originating from facet joints: our experience
Creators: name: Bennici, Calogero
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Interventional non-vascular
subject: Musculoskeletal spine
subject: CT
subject: MR
subject: Treatment effects
subject: Ablation procedures
subject: Athletic injuries

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of our study is to evaluate the effectiveness of the treatment of low back pain in patients with a diagnosis of facet joints syndrome, with the aid of infiltrative treatment with radiofrequency...
A Novel Codon Insert in Protease of Clade B HIV Type 1
Creators: name: Eron, Joseph
name: Richman, Douglas D.
name: Jordan, Parris S.
name: Poon, Art
name: Squires, Kathleen
name: Ignacio, Caroline
name: Smith, Davey M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: A novel combination of three codon inserts in the pol coding region of HIV-1 RNA was identified in a highly antiretroviral experienced study subject with HIV-1 infection. A one codon insert was observed in the protease region between codon 40 and 41 simultaneously with a two codon insert present in the reverse transcriptase region at codon 69.
Spatially quasi-periodic solutions of the Euler equation
Creators: name: Sun, Xu
name: Topalov, Peter
Publisher: name: arXiv
Year: 2022
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We develop a framework for studying quasi-periodic maps and diffeomorphisms on $\mathbb{R}^n$. As an application, we prove that the Euler equation is locally well posed in a space of quasi-periodic vector fields on $\mathbb{R}^n$. In particular, the equation preserves the spatial quasi-periodicity of the initial data. Several results on the analytic dependence of solutions on the time and the initial data are proved.
Expression of Latent HIV Induced by the Potent HDAC Inhibitor Suberoylanilide Hydroxamic Acid
Creators: name: Espeseth, Amy
name: Hazuda, Daria
name: Cheema, Manzoor
name: Parker, Daniel
name: Archin, Nancie M.
name: Margolis, David M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Histone deacetylases (HDACs) act on histones within the nucleosome-bound promoter of human immunodeficiency virus type 1 (HIV-1) to maintain proviral latency. HDAC inhibition leads to promoter expression and the escape of HIV from latency. We evaluated the ability of the potent inhibitor recently licensed for use in oncology, suberoylanilide hydroxamic acid (SAHA; Vorinostat), selective for Class I HDACs, to induce HIV promoter expression in cell lines and virus production from the resting CD4+ T cells of antiretroviral-treated, aviremic HIV-infected patients. In J89, a Jurkat T cell line infected with a single HIV genome encoding the enhanced green fluorescence protein (EGFP) within the HIV genome, SAHA induced changes at nucleosome 1 of the HIV promoter in chromatin immunoprecipitation (ChIP) assays in concert with EGFP expression. In the resting CD4+ T cells of antiretroviral-treated, aviremic HIV-infected patients clinically achievable exposures to SAHA induced virus outgrowth ex vivo. These results suggest that potent, selective HDAC inhibitors may allow improved targeting of persistent proviral HIV infection, and define parameters for in vivo studies using SAHA.