cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Different preparation of Sodium-DNA for bone tissue regeneration
Creators: name: Buffoli, Barbara
name: Albanese, Massimo
name: Nocini, Pier Francesco
name: Boninsegna, Ramon
name: Sancassani, Guido
name: Rodella, Luigi Fabrizio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Sodium-DNA; bone regeneration; calvaria

description: Current strategies for bone tissue regeneration involve the use of a wide range of biomaterials and synthetic bone substitutes; among them, Sodium-DNA could represent a new chance considering its osteoinductive properties (Nakamura et al., 2000; Bowler et a., 2001; Guizzardi et al., 2003; Guizzardi et al., 2007). The aim of this study was to evaluate the regenerative properties of two different preparation of Sodium- DNA (paste or liquid form) in a rat calvarial defect model. The cranium of each rat was shaved and a skin incision from the naso-frontal area to the external occipital protuberance was performed. The skin and the subcutaneous tissues were reflected to expose the full extent of the calvaria. Full-thickness 5X8 mm bone skull defects were made on each parietal region using piezoelectric surgery. Bone defects were filled with Sodium-DNA (paste or liquid form, Veritas, Brescia, Italy) alone or mixed with Bio-Oss (Geistlich, Wolhusen, Switzerland). Histomorphometric evaluation of bone regeneration was performed at the end of the treatments. The data obtained showed a time-dependent active bone healing process; however, differences in the use of past or liquid form were evident. These results suggest that Sodium-DNA could be considered an active biomaterial in bone regeneration, but an adequate formulation to obtain a better regenerative efficacy is needed.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
A Study of Active Galactic Nuclei in Low Surface Brightness Galaxies with Sloan Digital Sky Survey Spectroscopy
Creators: name: Mei, Lin
name: Yuan, Weimin
name: Dong, Xiaobo
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Active galactic nuclei (AGN) in low surface brightness galaxies (LSBGs) have received little attention in previous studies. In this paper, we present detailed spectral analysis of 194 LSBGs from the Impey et al. (1996) APM LSBG sample which have been observed spectroscopically by the Sloan Digital Sky Survey Data Release 5 (SDSS DR5). Our elaborate spectral analysis enables us to carry out, for the first time, reliable spectral classification of nuclear activities in LSBGs based on the standard emission line diagnostic diagrams in a rigorous way. Star-forming galaxies are common, as found in about 52% LSBGs. We find, contrary to some of the previous claims, that the fraction of galaxies containing an AGN is significantly lower than that found in nearby normal galaxies of high surface brightness. This is qualitatively in line with the finding of Impey et al. (2001). This result holds true even within each morphological type from Sa to Sc. LSBGs having larger central stellar velocity dispersions, or larger physical sizes, tend to have a higher chance to harbor an AGN. For three AGNs with broad emission lines, the black hole masses estimated from the emission lines are broadly consistent with the well known M-$σ_\ast$ relation established for normal galaxies and AGNs.
description: 5 tables and 14 figures
Una fascia di Kuiper extrasolare
Creators: Redazione Media Inaf
Publisher: name: Media Inaf
Year: 2015

Il disco si trova tra le 37 e le 55 unità astronomiche (5,5 e 8,2 miliardi di chilometri) dalla sua stella, più o meno  la stessa distanza della cintura di Kuiper dal Sole La luminosità del disco, che è dovuta alla luce delle stelle riflessa da essa, è anche coerente con una vasta gamma di composizioni di polvere, compresi i silicati e il ghiaccio presente nella fascia di Kuiper
title: Ð Ð°ÑÑÑÑ ÑÐ°Ð¹Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ»ÐµÐºÑÑÐ¾ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ 330/110 ÐºÐ
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐµÐ»ÐµÐ·Ð½ÑÐ¹, ÐÐ»ÐµÐºÑÐ°Ð½Ð´Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÑÐ»ÐµÐºÑÑÐ¾ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ°Ñ ÑÐ¸ÑÑÐµÐ¼Ð°
Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ°Ñ ÑÑÑÐ¾Ð¹ÑÐ¸Ð²Ð¾ÑÑÑ
ÑÑÑÐ°Ð½Ð¾Ð²Ð¸Ð²ÑÐ¸Ð¹ÑÑ ÑÐµÐ¶Ð¸Ð¼ ÑÐ°Ð±Ð¾ÑÑ
ÑÐ¾ÐºÐ¸ Ð½ÐµÑÐ¸Ð¼Ð¼ÐµÑÑÐ¸ÑÐ½Ð¾Ð³Ð¾ ÐºÐ¾ÑÐ¾ÑÐºÐ¾Ð³Ð¾ Ð·Ð°Ð¼ÑÐºÐ°Ð½Ð¸Ñ
Ð¿ÐµÑÐµÑ Ð¾Ð´Ð½ÑÐµ Ð¿ÑÐ¾ÑÐµÑÑÑ

description: ÐÐ¾ Ð²Ð²ÐµÐ´ÐµÐ½Ð¸Ð¸ ÑÐ¾ÑÐ¼Ð¸ÑÑÐµÑÑÑ ÑÐµÐ»Ñ Ð¸ Ð·Ð°Ð´Ð°Ð½Ð¸Ñ Ð¿ÑÐ¾ÐµÐºÑÐ°. Ð Ð¿ÐµÑÐ²Ð¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´Ð¸ÑÑÑ Ð²ÑÐ±Ð¾Ñ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð² ÑÐ»ÐµÐºÑÑÐ¾ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Ñ Ð¿ÑÐ¾Ð²ÐµÑÐºÐ¾Ð¹ Ð¿Ð¾ Ð´Ð¾Ð¿ÑÑÑÐ¸Ð¼ÑÐ¼ Ð½Ð¾ÑÐ¼Ð°Ð¼. ÐÐ¾ Ð²ÑÐ¾ÑÐ¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð²ÑÐ¿Ð¾Ð»Ð½ÑÐµÑÑÑ ÑÐ°ÑÑÐµÑ ÑÑÑÐ°Ð½Ð¾Ð²Ð¸Ð²ÑÐµÐ³Ð¾ÑÑ ÑÐµÐ¶Ð¸Ð¼Ð° ÑÐ»ÐµÐºÑÑÐ¾ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÑÑÐ½ÑÐ¼ ÑÐ¿Ð¾ÑÐ¾Ð±Ð¾Ð¼ Ð¸ Ð¿ÑÐ¸ Ð¿Ð¾Ð¼Ð¾ÑÐ¸ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð¾Ð³Ð¾ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ° RastrWin. Ð ÑÑÐµÑÑÐµÐ¹ Ð³Ð»Ð°Ð²Ðµ Ð¾ÑÑÑÐµÑÑÐ²Ð»ÑÐµÑÑÑ ÑÐ°ÑÑÐµÑ ÑÐ¾ÐºÐ¾Ð² Ð½ÐµÑÐ¸Ð¼Ð¼ÐµÑÑÐ¸ÑÐ½Ð¾Ð³Ð¾ ÐºÐ¾ÑÐ¾ÑÐºÐ¾Ð³Ð¾ Ð·Ð°Ð¼ÑÐºÐ°Ð½Ð¸Ñ. Ð Ð·Ð°ÐºÐ»ÑÑÐ¸ÑÐµÐ»ÑÐ½Ð¾Ð¹ Ð³Ð»Ð°Ð²Ðµ ÑÐ°ÑÑÑÐ¸ÑÑÐ²Ð°ÐµÑÑÑ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ°Ñ ÑÑÑÐ¾Ð¹ÑÐ¸Ð²Ð¾ÑÑÑ ÑÐ¸ÑÑÐµÐ¼Ñ Ð¸ Ð²ÑÐ¿Ð¾Ð»Ð½ÑÐµÑÑÑ ÐµÐµ Ð´Ð°Ð»ÑÐ½ÐµÐ¹ÑÐ°Ñ Ð¾Ð¿ÑÐ¸Ð¼Ð¸Ð·Ð°ÑÐ¸Ñ.
Universal scaling dynamics in a perturbed granular gas
Creators: name: Jabeen, Zahera
name: Rajesh, R.
name: Ray, Purusattam
Publisher: name: arXiv
Year: 2009
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the response of a granular system at rest to an instantaneous input of energy in a localised region. We present scaling arguments that show that, in $d$ dimensions, the radius of the resulting disturbance increases with time $t$ as $t^α$, and the energy decreases as $t^{-αd}$, where the exponent $α=1/(d+1)$ is independent of the coefficient of restitution. We support our arguments with an exact calculation in one dimension and event driven molecular dynamic simulations of hard sphere particles in two and three dimensions.
description: 5 pages, 5 figures
Some measurements of heat transfer to air flowing parallel to a tube bundle in square array
Creators: name: Chandrasekharan, Kuppanna
Publisher: name: University of British Columbia
Year: 2012

description: Heat transfer measurements were made in a heat exchanger where air flows parallel to an unbaffled tube bundle and where steam is condensing inside the tubes. The tubes were one-inch outside diameter and were arranged in a square lattice with one-inch clearance between adjacent tubes. The Reynolds Number range covered in this investigation was 630 - 8220. Pseudo-j(h)-factors have been calculated for the air film in the central unit cell and are presented along with the results of Miller et al and Inayatov and Mikeev, who worked with other lattice arrangements. The present data are insufficiently numerous and too unreliable for empirical correlation, but they do show a trend which is consistent with the work of the above investigators. The temperature measurements showed an apparent dissymmetry inside the shell of the heat exchanger, and suggestions are made for the improvement of these measurements for more dependable results. Further work that can be done, using the present set-up with slight modifications, is also cited.
Colour centres in alkali metal azides
Creators: name: Pringle, John Peter Scott
Publisher: name: University of British Columbia
Year: 2012

description: Previous work by Heal had shown that X-irradiated sodium azide crystals dissolved in water produced small amounts of nitrogen gas, hydroxyl ion and ammonia, thereby indicating that some decomposition had occurred. Heal also observed colours in the material, similar to those of the X-irradiated alkali halides for which a whole series of colour centres responsible have been postulated. It was therefore decided to investigate the colour centres of the alkali azides, partly to extend the colour centre research, and partly to illuminate the X-ray decomposition processes. Crystalline plates of NaN₃, KN₃, RbN₃ and CsN₃ were irradiated at liquid nitrogen and room temperature, using a Machlett AEG-50 tungsten target X-ray tube, operated at 50 KVP. The absorption spectra of the irradiated samples were measured at liquid nitrogen temperature with a Cary model 14 recording spectrophotometer. The low temperature spectra consisted of three bands. The A band, peaking at 612, 568, 578 and 592 mu for NaN₃, KN₃, RbN₃ and CsN₃, respectively, is ascribed to F centres. The anomalous sodium azide band is related to its trigonal crystal structure, differing from the body centred tetragonal of the other azides. The B band, peaking at 361, 374 and 390 mu for KN₃, RbN₃ and CsN₃ respectively, was strong and triple, there being shoulders about 30 mu on each side of the main peak. For NaN₃ it was weak, single and peaked near 330 mu. Tentatively, it is ascribed to the centre. The C band, peaking about 740, 790, 820 and 850 mu for NaN₃, KN₃, RbN₃ and CsN₃ is weak and single. It may be due to F1 centres. The room temperature spectra were strikingly different from each other, except for RbN₃ and CsN₃. For NaN₃ five bands were observed at 342, 560, 630 , 730 and 860 mu; the latter four were weak and may be an electronic vibrational spectrum. The strong 342 mu band is ascribed to the presence of sodium metal in some non-colloidal form; a correlation between the band and the ionisation potential of the metal is noted. In KN₃ three bands at 760 (strong), 590 (strong shoulder) and 340 mu (weak) were obtained. The first two are ascribed to small F centre aggregates of the M,R type though no definite assignations are made. RbN₃ and CsN₃ spectra both consist of a broad peak showing fine structure, the highest peaks occurring at 330 mu and 375 mu respectively. It is considered uncertain that all the absorption is due to the impurity held responsible for the fine structure.
Atlas rotation and mandibular deviation by Cone Beam CT
Creators: name: Buffoli, Barbara
name: Cocchi, Marco Angelo
name: Papini, Andrea
name: Labanca, Mauro
name: Galli, Massimo
name: Tschabitscher, Manfred
name: Rodella, Luigi Fabrizio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Atlas; mandible; CBCT.

description: Cervical vertebrae and mandible are functionally related and some evidences suggest a strong correlation between their relative position and orientation (Huggare et al., 1996; Nisayif et al., 2005). In this study TC Dental Scan with cone beam technology was used to study the relationship between atlas and mandibular rotation in 205 patients. Using a digitalized images analyser, we calculated the axial rotation of atlas and mandible, measuring the angle with respect to the frontal plane. We found that 80.98% of patients presented the axial rotation of the mandible in the same direction of atlas rotation compared with 19.02% of patients that presented opposite directions. Among the consistent group, 71.08% of patients had a left rotation compared with 28.92% that had a right rotation. Moreover, considering the absolute values of the rotation, we observed that the atlas had a more marked rotation with respect to the mandible and that the values of left rotations were higher with respect to the value recorded for right rotations both for the mandible and atlas measurements. This study represents a starting point to better characterize the relationship between atlas and mandible; further studies are necessary to better understand the importance of this data from a functional and clinical point of view.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Una partnership cosmica
Creators: Corrado Ruscica
Publisher: name: Media Inaf
Year: 2015

Supernovae e buchi neri potrebbero rappresentare una specie di 'impresa di pulizie' cosmica. E' quanto emerge da uno studio pubblicato su Astrophysical Journal Letters secondo cui la violenta attività dei buchi neri supermassicci potrebbe spianare la strada alle supernovae per ripulire le galassie dal gas, interrompendo così la nascita di nuove stelle
Mobility and asymmetry effects in one-dimensional rock-paper-scissors games
Creators: name: Venkat, Siddharth
name: Pleimling, Michel
Publisher: name: arXiv
Year: 2010
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: As the behavior of a system composed of cyclically competing species is strongly influenced by the presence of fluctuations, it is of interest to study cyclic dominance in low dimensions where these effects are the most prominent. We here discuss rock-paper-scissors games on a one-dimensional lattice where the interaction rates and the mobility can be species dependent. Allowing only single site occupation, we realize mobility by exchanging individuals of different species. When the interaction and swapping rates are symmetric, a strongly enhanced swapping rate yields an increased mixing of the species, leading to a mean-field like coexistence even in one-dimensional systems. This coexistence is transient when the rates are asymmetric, and eventually only one species will survive. Interestingly, in our spatial games the dominating species can differ from the species that would dominate in the corresponding nonspatial model. We identify different regimes in the parameter space and construct the corresponding dynamical phase diagram.
description: 6 pages, 5 figures, to appear in Physical Review E
RCW 34: è qui la festa?
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2015

Quando l'idrogeno caldo raggiunge il bordo della nube di gas si lancia fuori nel vuoto, come una bottiglia di spumante quando viene stappata.  L'idrogeno ionizzato ha un importante ruolo in astronomia perché indica le regioni di formazione stellare
Building astroBERT, a language model for Astronomy & Astrophysics
Creators: name: Grezes, Felix
Publisher: name: Zenodo
Year: 2021
Subjects: Astrophysics Data System (ADS)
machine learning

description: The existing search tools for exploring the NASA Astrophysics Data System (ADS) can be quite rich and empowering (e.g., similar and trending operators), but researchers are not yet allowed to fully leverage semantic search.
 For example, a query for "results from the Planck mission" should be able to distinguish between all the various meanings of Planck (person, mission, constant, institutions and more) without further clarification from the user.
 At ADS, we are applying modern machine learning and natural language processing techniques to our dataset of recent astronomy publications to train astroBERT, a deeply contextual language model based on research at Google.
 Using astroBERT, we aim to enrich the ADS dataset and improve its discoverability, and in particular we are developing our own named entity recognition tool. We present here our preliminary results and lessons learned.
High Q Cavity Induced Fluxon Bunching in Inductively Coupled Josephson Junctions
Creators: name: Madsen, Søren
name: Grønbech-Jensen, Niels
name: Pedersen, Niels Falsig
name: Christiansen, Peter L.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We consider fluxon dynamics in a stack of inductively coupled long Josephson junctions connected capacitively to a common resonant cavity at one of the boundaries. We study, through theoretical and numerical analysis, the possibility for the cavity to induce a transition from the energetically favored state of spatially separated shuttling fluxons in the different junctions to a high velocity, high energy state of identical fluxon modes.
description: 8 pages, 5 figures
Belle addormentate, una favola di scienza
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2015

Analizzando il tempo trascorso fra la data di pubblicazione e il picco delle citazioni di 22 milioni di articoli scientifici, uno studio mostra che le cosiddette “sleeping beauties” non sono affatto rare. E che s’incontrano soprattutto nel campo della chimica e della fisica. Abbiamo intervistato uno degli autori, Alessandro Flammini
title: ÐÐ»Ð³Ð¾ÑÐ¸ÑÐ¼ ÑÐµÑÐµÐ½Ð¸Ñ Ð¿ÑÑÐ¼Ð¾Ð¹ Ð·Ð°Ð´Ð°ÑÐ¸ Ð¾ Ð²ÑÑÑÐµÑÐµ Ð´Ð²ÑÑ ÑÐµÐ», Ð´Ð²Ð¸Ð¶ÑÑÐ¸Ñ ÑÑ Ð² Ð²ÑÐ·ÐºÐ¾Ð¹ ÑÐ»Ð¾Ð¸ÑÑÐ¾Ð¹, ÑÐ»Ð°Ð±Ð¾ÑÐ¶Ð¸Ð¼Ð°ÐµÐ¼Ð¾Ð¹ Ð¶Ð¸Ð´ÐºÐ¾Ð¹ ÑÑÐµÐ´Ðµ
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ¸ÐºÑÐ»ÐµÐ²Ð°, ÐÐºÐ°ÑÐµÑÐ¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸ÐµÐ¼
Ð²ÑÑÐ°Ð»ÐºÐ¸Ð²Ð°ÑÑÐ°Ñ ÑÐ¸Ð»Ð°
Ð¿Ð¾Ð´ÑÑÐ¼Ð½Ð°Ñ ÑÐ¸Ð»Ð° ÐºÑÑÐ»Ð°

description: Ð ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð° Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ°Ñ Ð¼Ð¾Ð´ÐµÐ»Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸ÐµÐ¼ Ð°Ð²ÑÐ¾Ð½Ð¾Ð¼Ð½Ð¾Ð³Ð¾ ÑÐ²ÐµÑÐ´Ð¾Ð³Ð¾ ÑÐµÐ»Ð°, Ð´Ð²Ð¸Ð¶ÑÑÐµÐ³Ð¾ÑÑ Ð² Ð²ÑÐ·ÐºÐ¾Ð¹ Ð½ÐµÑÐ¶Ð¸Ð¼Ð°ÐµÐ¼Ð¾Ð¹ ÑÑÑÐ°ÑÐ¸ÑÐ¸ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð¹ Ð¶Ð¸Ð´ÐºÐ¾ÑÑÐ¸, Ð° ÑÐ°ÐºÐ¶Ðµ Ð°Ð½Ð°Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð¸ ÑÐ¸ÑÐ»ÐµÐ½Ð½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÑÐ¾Ð¹ Ð¼Ð¾Ð´ÐµÐ»Ð¸. ÐÑÐµÐ´Ð¿Ð¾Ð»Ð°Ð³Ð°ÐµÑÑÑ, ÑÑÐ¾ ÑÐµÐ»Ð¾ Ð½Ðµ Ð¸Ð¼ÐµÐµÑ ÑÐ¾Ð±ÑÑÐ²ÐµÐ½Ð½Ð¾Ð¹ Ð´Ð²Ð¸Ð³Ð°ÑÐµÐ»ÑÐ½Ð¾Ð¹ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐ¸, Ð½Ð¾ Ð¾ÑÐ½Ð°ÑÐµÐ½Ð¾ ÑÐ¿ÑÐ°Ð²Ð»ÑÐµÐ¼ÑÐ¼Ð¸ ÑÑÐ»ÑÐ¼Ð¸ - ÐºÑÑÐ»ÑÑÐ¼Ð¸ ÐºÐ¾Ð½ÐµÑÐ½Ð¾Ð³Ð¾ ÑÐ°Ð·Ð¼Ð°ÑÐ°. ÐÐ½Ð¾ Ð¿ÐµÑÐµÐ¼ÐµÑÐ°ÐµÑÑÑ Ð¿Ð¾Ð´ Ð´ÐµÐ¹ÑÑÐ²Ð¸ÐµÐ¼ Ð²ÑÑÐ°Ð»ÐºÐ¸Ð²Ð°ÑÑÐµÐ¹ ÑÐ¸Ð»Ñ ÐÑÑÐ¸Ð¼ÐµÐ´Ð° Ð¸ Ð¿Ð¾Ð´ÑÑÐ¼Ð½Ð¾Ð¹ ÑÐ¸Ð»Ñ ÐºÑÑÐ»Ð°. Ð£Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ Ð¾ÑÑÑÐµÑÑÐ²Ð»ÑÐµÑÑÑ Ð¿ÑÑÐµÐ¼ Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ ÑÐ³Ð»Ð° Ð°ÑÐ°ÐºÐ¸ ÐºÑÑÐ»Ð° Ñ ÑÐµÐ»ÑÑ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ Ð²ÑÑÐ¾Ð´Ð° ÑÐµÐ»Ð° Ð² Ð¾ÐºÑÐµÑÑÐ½Ð¾ÑÑÑ Ð·Ð°Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ¾ÑÐºÐ¸ Ð¿Ð¾Ð²ÐµÑÑÐ½Ð¾ÑÑÐ¸. ÐÐ²Ð¸Ð¶ÐµÐ½Ð¸Ðµ ÑÐµÐ»Ð° ÑÑÐ¸ÑÐ°ÐµÑÑÑ Ð¿Ð»Ð¾ÑÐºÐ¾Ð¿Ð°ÑÐ°Ð»Ð»ÐµÐ»ÑÐ½ÑÐ¼. Ð Ð¾ÑÐ½Ð¾Ð²Ñ Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð¿Ð¾Ð»Ð¾Ð¶ÐµÐ½Ñ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ, ÑÐ°Ð½ÐµÐµ Ð¾Ð¿ÑÐ±Ð»Ð¸ÐºÐ¾Ð²Ð°Ð½Ð½ÑÐµ Ð² ÑÐ°Ð±Ð¾ÑÐ°Ñ Ð¤Ð¸ÑÑÐ¾Ð²Ð° Ð.Ð. Ð¸ ÐÑÐ·Ð½ÐµÑÐ¾Ð²Ð¾Ð¹ Ð.Ð.
title: Ð£Ð»ÑÑÑÐµÐ½Ð¸Ðµ Ð¼Ð°Ð½ÐµÐ²ÑÐµÐ½Ð½Ð¾ÑÑÐ¸ ÐºÐ¾Ð»ÐµÑÐ½ÑÑ Ð¼Ð°ÑÐ¸Ð½ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸ÐµÐ¼ ÑÐ¿ÑÐ°Ð²Ð»ÑÐµÐ¼Ð¾Ð³Ð¾ Ð¼ÐµÑ Ð°Ð½Ð¸Ð·Ð¼Ð° ÑÐ°ÑÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ Ð¼Ð¾ÑÐ½Ð¾ÑÑÐ¸
title: ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÑ 05.02.02 "ÐÐ°ÑÐ¸Ð½Ð¾Ð²ÐµÐ´ÐµÐ½Ð¸Ðµ, ÑÐ¸ÑÑÐµÐ¼Ñ Ð¿ÑÐ¸Ð²Ð¾Ð´Ð¾Ð² Ð¸ Ð´ÐµÑÐ°Ð»Ð¸ Ð¼Ð°ÑÐ¸Ð½"
titleType: Subtitle
Creators: name: ÐÐ¸Ð´Ð¸ÐºÐ¾Ð², Ð Ð¾Ð¼Ð°Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: ÐÐ¾Ð»ÐµÑÐ½ÑÐµ Ð¼Ð°ÑÐ¸Ð½Ñ
ÐÐ²ÑÐ¾Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½ÑÐµ Ð´Ð¸ÑÑÐµÑÐµÐ½ÑÐ¸Ð°Ð»Ñ
Ð¢ÑÐ°ÐºÑÐ¾ÑÐ½ÑÐµ Ð´Ð¸ÑÑÐµÑÐµÐ½ÑÐ¸Ð°Ð»Ñ
ÐÐ¸ÑÑÐµÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½ÑÐµ Ð¿ÐµÑÐµÐ´Ð°ÑÐ¸

description: Ð Ð°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐµ Ð¿Ð¾Ð´ÑÐ¾Ð´Ð¾Ð² Ðº Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð², Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼ÑÑ Ð´Ð»Ñ ÑÐ¸Ð½ÑÐµÐ·Ð° ÐºÐ¸Ð½ÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÑÐµÐ¼ ÑÐ¿ÑÐ°Ð²Ð»ÑÐµÐ¼ÑÑ Ð¼ÐµÑÐ°Ð½Ð¸Ð·Ð¼Ð¾Ð² ÑÐ°ÑÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ Ð¼Ð¾ÑÐ½Ð¾ÑÑÐ¸ ÐºÐ¾Ð»ÐµÑÐ½ÑÑ Ð¼Ð°ÑÐ¸Ð½. Ð ÐµÑÐ°ÐµÑÑÑ Ð·Ð°Ð´Ð°ÑÐ° Ð¿Ð¾ ÑÐ½Ð¸Ð¶ÐµÐ½Ð¸Ñ Ð½Ð°Ð³ÑÑÐ·ÐºÐ¸ Ð½Ð° Ð³Ð¸Ð´ÑÐ¾ÑÐ¸Ð»Ð¸Ð½Ð´ÑÑ Ð¼ÐµÑÐ°Ð½Ð¸Ð·Ð¼Ð° Ð¿Ð¾Ð²Ð¾ÑÐ¾ÑÐ°, Ð° ÑÐ°ÐºÐ¶Ðµ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ Ð¼Ð°Ð½ÐµÐ²ÑÐµÐ½Ð½Ð¾ÑÑÐ¸ ÑÑÐ°ÐºÑÐ¾ÑÐ° Ñ ÑÐ°ÑÐ½Ð¸ÑÐ½Ð¾-ÑÐ¾ÑÐ»ÐµÐ½ÐµÐ½Ð½Ð¾Ð¹ ÑÐ°Ð¼Ð¾Ð¹ Ð·Ð° ÑÑÐµÑ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð¼ÐµÑÐ°Ð½Ð¸Ð·Ð¼Ð° ÑÐ°ÑÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ Ð¼Ð¾ÑÐ½Ð¾ÑÑÐ¸ Ñ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÑÑ ÑÐ¿ÑÐ°Ð²Ð»ÑÐµÐ¼Ð¾Ð³Ð¾ ÑÐ°ÑÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ ÑÐ¸Ð» ÑÑÐ³Ð¸ Ð¼ÐµÐ¶Ð´Ñ Ð²ÐµÐ´ÑÑÐ¸Ð¼Ð¸ ÐºÐ¾Ð»ÐµÑÐ°Ð¼Ð¸.
Solving the 0-1 Multidimensional Knapsack Problem with Resolution Search
Creators: name: Boussier, Sylvain
name: Vasquez, Michel
name: Vimont, Yannick
name: Hanafi, Said
name: Michelon, Philippe
Publisher: name: arXiv
Year: 2009
Subjects: subject: Discrete Mathematics (cs.DM)
subject: FOS: Computer and information sciences

description: We propose an exact method which combines the resolution search and branch & bound algorithms for solving the 0?1 Multidimensional Knapsack Problem. This algorithm is able to prove large?scale strong correlated instances. The optimal values of the 10 constraint, 500 variable instances of the OR-Library are exposed. These values were previously unknown.
Google Doodle per Sally Ride
Creators: Davide Coero Borga
Publisher: name: Media Inaf
Year: 2015

Il motore di ricerca celebra Sally Ride, la prima astronauta statunitense a raggiungere lo spazio nel 1983. Prima di lei due donne sovietiche, Tereškova e Savickaja. Oggi Samantha Cristoforetti è la prima italiana fra le stelle
Human The Distal Perforators Of Posterior Tibial Artery. A Study For The Correct Planning Of Medial Lower Leg Flaps
Creators: name: Bulla, Antonio
name: Bandiera, Pasquale
name: Casoli, Vincent
name: Campus, Gian Vittorio
name: Montella, Andrea
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Tibial artery; perforator flaps; injection techniques.

description: The adipofascial flap, introduced by Lin in 1994 (1), has many advantages compared to fasciocutaneous or free flaps for lower limb reconstruction. Its dissection is relatively easy and fast with low donor site morbidity and it doesn’t alter the shape of the leg. The aim of this dissection study is to evaluate the anatomic localization of the most distal perforator of the posterior tibial vessels to provide an anatomical rationale for the safe harvesting of distally based medial adipofascial flaps of the leg.
Thirty lower limbs from 15 cadavers were used for this study. In all the limbs, the femoral artery was cannulated. Different techniques of injection were employed. 26 specimens were injected with latex to fill the entire vascular network and ease dissection. 3 specimens were injected with a mixture of barium sulphate and gelatin and underwent a CT scan. CT scan dataset were used to make 3D reconstruction. They underwent anatomical dissection after the scan. 1 Specimen was injected with red epoxy resin mixed with barium sulphate (2). This technique is aimed to perform comparative anatomical vascular studies between CT three-dimensional reconstructions and traditional dissection techniques.
A distal perforator was found in all specimens; the mean caliber was 0.77 mm. In all cases, the perforator artery passed in the septum between flexor hallucis longus m. and flexor digitorum longus m. and was accompanied by two veins. In our series, the distance between the lowest perforator and the medial malleolus ranged from 3.5 to 8.2 cm. The median was 6.75 cm, the 5th percentile 4 cm and the 95th percentile 8.1 cm. The mean distance of the perforator from the medial tibial border was 1.23 cm. The mean ratio between the distance of perforator from the medial malleolus and the total leg length was 21%.
Compared to all previous researches (3), our study has found more distal perforators from posterior tibial perforator artery. This fact may have important clinical consequences because the anteromedial adipofascial flap would cover more distal soft tissue defects. Moreover, our data suggest some safety parameters to make the rising of a medial adipofascial leg flap safer in surgical practice.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
title: ÐÐµÑÐ²Ð½ÑÐµ ÑÑÐ½ÐºÑÐ¸Ð¸. ÐÐµÐºÑÐ¸Ñ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ð¹ "ÐÑÐ¸ÐºÐ»Ð°Ð´Ð½Ð°Ñ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÐºÐ° Ð¸ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸ÐºÐ°", "ÐÐµÑ Ð°Ð½Ð¸ÐºÐ° Ð¸ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ", "ÐÐ°ÑÐµÐ¼Ð°ÑÐ¸ÐºÐ° Ð¸ ÐºÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½ÑÐµ Ð½Ð°ÑÐºÐ¸"
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÐ¾Ð¸ÑÐµÐµÐ², ÐÐ»ÐµÐºÑÐµÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: ÐÐ°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð°Ð½Ð°Ð»Ð¸Ð·
ÐÑÐ¾Ð±ÑÐ°Ð¶ÐµÐ½Ð¸Ñ (Ð¼Ð°Ñ.)

description: Ð£ÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²ÑÐµÑ Ð¤ÐÐÐ¡ ÐÐ Ð¿Ð¾ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½Ðµ "ÐÐ°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð°Ð½Ð°Ð»Ð¸Ð·" Ð¿Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸ÑÐ¼ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ 01.03.02 "ÐÑÐ¸ÐºÐ»Ð°Ð´Ð½Ð°Ñ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÐºÐ° Ð¸ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸ÐºÐ°", 01.03,03 "ÐÐµÑÐ°Ð½Ð¸ÐºÐ° Ð¸ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ", 02.03.01 "ÐÐ°ÑÐµÐ¼Ð°ÑÐ¸ÐºÐ° Ð¸ ÐºÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½ÑÐµ Ð½Ð°ÑÐºÐ¸". Ð Ð°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÐµÑÑÑ ÑÐµÐ¼Ð°, Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÑÑÑÐ°Ñ Ð´Ð¾ÑÑÐ°ÑÐ¾ÑÐ½ÑÐµ ÑÑÑÐ´Ð½Ð¾ÑÑÐ¸ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð². Ð¢ÐµÐ¼Ð° Ð¸Ð·Ð»Ð°Ð³Ð°ÐµÑÑÑ ÑÑÐ¸Ð»ÐµÐ¼, ÑÐ¾Ð³Ð»Ð°ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¼ Ñ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ð¸ÐµÐ¼ ÑÐ¼ÐµÐ¶Ð½ÑÑ Ð²Ð¾Ð¿ÑÐ¾ÑÐ¾Ð² Ð² ÐºÑÑÑÐµ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² ÐÐÐÐ.
Melatonin effects in normal and tumoral skeletal muscle cells: a preliminary study
Creators: name: Burattini, Sabrina
name: Salucci, Sara
name: Battistelli, Michela
name: Curzi, Davide
name: Giordano, Francesco Maria
name: Codenotti, Silvia
name: Fanzani, Alessandro
name: Falcieri, Elisabetta
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Melatonin; C2C12 and RH30 cells; anti-apoptotic and pro-apoptotic effect; morphology.

description: Melatonin (MEL), also chemically known as N-acetyl-5-methoxytryptamine, is a hormone found in animals, plants, and microbes. It exhibits strong antioxidant effects and thanks to its structure it is able to diffuse through all the biological membranes, also overcoming the blood-brain barrier and the placenta (Salucci et al., 2014). Numerous in vitro and in vivo studies have documented Mel ability to induce apoptosis in tumor cells while inhibiting it in the normal ones (Cristofanos et al, 2009; Lanoix et al., 2011).
In this study MEL activity has been investigated in vitro both in murine skeletal muscle (C2C12) and in alveolar rhabdomyosarcoma (RH30) cell lines by means of morpho-functional approaches. If MEL low concentrations are well tolerated by normal skeletal muscle cells, its effect appears completely different in tumor cells, where MEL can be considered a powerful apoptotic trigger. In RH30 cells, blebbing, chromatin condensation and margination, apoptotic bodies occur as well as necrotic cell death features. The latter appeared after prolonged exposure to MEL. In conclusion, the neuro-hormone shows a strong dose and time dependent pro-apoptotic activity and it could represent a potential tool in association with the current chemotherapeutic compounds to resolve alveolar rhabdomyosarcoma, the most common pediatric skeletal muscle tissue malignancy.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Una curiosa famiglia di esopianeti giganti
Creators: Corrado Ruscica
Publisher: name: Media Inaf
Year: 2015

Due nuovi pianeti massicci sono stati scoperti attorno ad una gigante rossa. Si tratta di due gioviani-caldi di cui uno in particolare, Kepler-432b, presenta delle stranezze. Secondo i ricercatori, il pianeta potrebbe rappresentare un caso raro oppure potrebbe far parte di una comune classe di esopianeti che vengono di solito distrutti man mano che le loro stelle ospiti evolvono. I risultati su Astrophysical Journal
Time-dependent Generalized SIC-OEP formalism and Generalized SIC-Slater approximation
Creators: name: Messud, J.
name: Dinh, P. M.
name: Reinhard, P. -G.
name: Suraud, E.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Quantum Physics (quant-ph)
subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: FOS: Physical sciences

description: We propose a simplification of the full "2 sets" Time dependent Self Interaction Correction (TD-SIC) method, applying the Optimized Effective Potential (OEP) method. The new resulting scheme is called time-dependent "Generalized SIC-OEP". A straightforward approximation, using the spatial localization of one set of orbitals, leads to the "Generalized SIC-Slater" formalism. We show that it represents a great improvement compared to the traditional SIC-Slater/KLI formalisms.
description: 5 pages, 3 figures
Broad HI absorption in the candidate binary black-hole 4C37.11 (B2 0402+379)
Creators: name: Morganti, Raffaella
name: Emonts, Bjorn
name: Oosterloo, Tom
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report the discovery of extremely broad 21-cm HI absorption (FWZI ~1600 km/s) detected with the Westerbork Synthesis Radio Telescope in the radio source 4C37.11 (B2 0402+379). This object has been claimed to host a super-massive binary black hole (Rodriguez et al. 2006). The main features in the absorption profile are two components, separated by ~1100 km/s. The HI absorption in 4C37.11 is unusual because it is the first case where such broad absorption is found to be centred on the systemic velocity of the host galaxy and not asymmetric and blueshifted as is seen in all other galaxies with broad HI absorption. Given the large width of the absorption, we suggest that a possible explanation for the extreme properties of the HI absorption is that it is the kinematic signature of a binary black hole. If this interpretation is correct, the combined black hole mass derived from the absorption profile is consistent with that derived from the luminosity of the spheroid. If the broad absorption is indeed due to a binary black hole, this finding confirms the importance of the gaseous component in the merging process of supermassive black holes.
description: Accepted for publication in A&A Letter, 4 pages, 2 figures
A histological study of eosinophilic granuloma in mice following infestation with Anisakis larvae
Creators: name: Caldara, Gaetano Felice
name: Alongi, Angela
name: Chetta, Michele
name: Ferrantelli, Vincenzo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Anisakis; Anisakidosis; nematode; rat; eosinophilic granuloma; fish; anthropozoonosis.

description: Anisakidosis is a parasitic anthropozoonosis caused by the nematode larvae of the Anisakidae family. Anisakid nematodes belonging to the Anisakis pegreffii are highly prevalent in several fish species living in the Mediterranean sea. The larvae can accidentally infect humans following the ingestion of infected raw or undercooked sea fish. A migrating larva causes a clinical disease when it invades the stomach or intestinal wall and peritoneum, mimicking an eosinophilic gastroenteritis or an ulcer. In this preliminary experiment, the histopathology of the newly-formed parasitic granulomas in mice infested with third stage Anisakis pegreffii larvae, was studied and described.
The larvae were morphologically identified as Anisakis type I by the presence of a boring tooth and a mucron, without ventriculus and caecum. The larval DNA was extracted and amplified by polymerase chain reaction (PCR). After PCR, the samples were processed to undergo restriction fragment length polymorphism analysis (RFLP). This was done to scan the restriction profiles for genetic identification. PCR products were purified and sequenced. The sequences were analysed to detect the relationship between nucleotides and perform a phylogenetic analysis.
The paraffin-embedded granuloma samples showed worms having a diameter of 0.55 mm x 0.37 mm, polymyarian muscle cells and a circular intestine. The histological profiles showed a primary lesion at the site of anisakid penetration marked by oedema and neutrophil and eosinophil infiltration. The presence of histiocytes or epithelioid histiocytes, lymphocytes, monocytes, and plasma cells was also possible. Fibrinous exudation, hemorrhage, or vascular damage were detected within the first week of the acute intestine infection with a massive eosinophilic infiltration. Two weeks after the infestation, the infiltrating host cells formed a granuloma in the tissue surrounding the penetrated worm mainly consisting of eosinophils, a large number of fibroblasts and a varying number of admixed multinucleated giant cells.
In order to explain the origin of the eosinophilic granulomas, a study into the produced substance attracting eosinophils and other host white blood cells to the area will carry out.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Crateri a perdita d’occhio su Rea
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2015

L'immagine è stata scattata usando la narrow-angle camera (NAC) lo scorso 10 febbraio 2015 durante l'ultimo flyby da una distanza di circa 56mila chilometri. La superficie di Rea è scolpita da crateri da impatto
Biocompatibility evaluation of PLLA scaffolds for vascular tissue engineering
Creators: name: Caldara, Gaetano
name: Rigogliuso, Salvatrice
name: Carfì Pavia, Francesco
name: Brucato, Valerio
name: Ghersi, Giulio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Poly-L-lactic acid; (PLLA); biocompatibility; immune responce; implant; scaffold; angiogenesis

description: Poly-L-lactic acid (PLLA), a hemicrystalline material, has been extensively studied in applications of engineered tissues, because it is biodegradable, absorbable and it supports cell attachment and growth. The purpose of this study is to evaluate tissue/ material interactions, neovascularization and the biocompatibility of PLLA by optical and scanning electron microscopy in a model of animal implant. PLLA porous disks were implanted into the dorsal subcutis of BALB/C mice for 1, 2, 3, and 8 weeks. The bioptic samples of excised PLLA and the surrounding tissue were evaluated for inflammatory response and tissue ingrowth. The samples were divided in two halves: one was fixed in neutral buffered formaldehyde for 24 hours, embedded in parraffin blocks, and cut into 8-μm-thick sections. The other half was fixed with 4% glutaraldehyde, dehydrated, gold coated, and was then observed with an scanning electron microscope (FEGESEM QUANTA 200 FEI). The anatomopathological examination of the implant site revealed no significant inflammatory response. The histological analysis revealed a thin fibrous capsule and a minimal inflammatory reaction with polymorphonuclear leukocytes, lymphocytes, monocytes and plasma cells around the implant, which died out during the second week. The presence of neutrophils and lymphocytes was detected until the second week after the implantation and a trama of connective tissue was found on the pores of the scaffold during the first week. The presence of giant cells was detected in the final stage of the inflammatory response and healing, which mainly occurred during the second week after the implantation. In addition, a significant angiogenic activity on the external implant surface was observed during the third week. 8 weeks after the implant, the inflammatory cell response was absolutely minimal, with an intense angiogenic activity occurring within the scaffold. This study shows the following results: PLLA has a high degree of biocompatibility and angiogenic potential; moreover, scaffolds are biocompatible in terms of cell survival and proliferation, as they stimulate a minimal inflammatory response while supporting cell infiltration, the matrix apposition and neo vascularization.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
L’ingarbugliata galassia NGC 6240
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2015

Questo pasticcio galattico è il risultato della fusione di due galassie e dell'avvicinamento dei loro buchi neri supermassicci. Per questo l'oggetto adesso non ha ancora una forma ben definita: polvere, gas e stelle circondano il nucleo della fusione\
Kinetics of the reaction between formic acid and permanganate in queous acid solution.
Creators: name: Taylor, Sandra Margaret
Publisher: name: University of British Columbia
Year: 2012

description: The kinetics of the oxidation of formic acid by permanganate in aqueous perchloric acid solution, i.e., 2MnO¯₄ + 3HCOOH + 2H⁺ → 2MnO₂ + 3CO₂ + 4H₂O were studied in the temperature range 15 to 35°C. The variables examined included the reactant and hydrogen ion concentrations, ionic strength, the presence of various metal ions, and solvent and reactant deuterium isotope effects. The reaction appears to proceed through two independent paths in which the rate-determining steps are bimolecular reactions of permanganate with formic acid and with formate ion, respectively. The kinetics are thus of the form -d [MnO₄¯] / dt = [M nO₄¯] [HCOOH] (kA + kBKi / [H⁺] ) where kA and kg are rate constants of the two bimolecular reactions involving formic acid and formate ion, respectively, and Ki is the ionization constant of formic acid. The Arrhenius expressions for the rate constants were found to be kA = 1.1 x 10⁹exp. (-16400/RT) 1.mole¯¹sec¯¹ and kB = 7.8 x 10⁹exp. (-13000/RT) 1.mole¯¹sec¯¹. The formate ion reaction exhibits a large deuterium (HCOO¯:DCOO¯) isotope effect which suggests cleavage of the C-H bond in the rate-determining step. The absence of a corresponding isotope effect in the formic acid reaction suggests that it proceeds by a different mechanism. Fe⁺⁺⁺(but not Ag⁺, Cu⁺⁺, Co⁺⁺ or Na⁺) was found to catalyze the reaction, possibly by a mechanism involving a FeMnO₄⁺⁺ complex. Previous investigations of the formic acid-permanganate system have been confined to lower acidities than the present one, and only the formate ion contribution to the reaction had been detected.
A novel copper compound, CuNV110, induces apoptosis in tumor cells by dissociation of the Hsp60- pro-caspase 3 complex
Creators: name: Campanella, Claudia
name: Marino Gammazza, Antonella
name: Caruso Bavisotto, Celeste
name: Nikolic, Dragana
name: Palumbo Piccionello, Antonio
name: Barone, Giampaolo
name: Pace, Andrea
name: Zummo, Giovanni
name: Cappello, Francesco
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Respiratory cells; pulmonary cancer; Hsp60; caspase 3; apoptosis.

description: The biological activity of CuNV1110, a novel copper chemical compound, has been recently studied on cancer cells and it has been showed that it reduces the cell viability, in a dose and time dependent manner, and induces cell apoptosis. In this study we evaluated the possible mechanisms by which CuNV1110 induces cell apoptosis. In particular we looked at its effects on Hsp60 levels and caspase 3 activation. We used an in vitro model of a pulmonary mucoepidermoid carcinoma (NCI-H292 cells). We found that CuNV1110 reduces the cell viability and induces cell apoptosis in a dose/time dependent manner. Then, we found that Hsp60 levels decrease with the increasing concentrations of CuNV110; by contrast, caspase 3 levels increased. Interestingly, we found by immunoprecipitation a complex between Hsp60 and procaspase 3 in untreated cells that dissociate with increasing doses of CuNV110. These data demonstrate that CuNV1110 can dissociate the anti-apoptotic complex between Hsp60 and pro-caspase 3 in NCI-H292, in turn inducing apoptosis of tumor cells. If confirmed in other cell lines, CuNV1110 will be tested as anticancer drug by in vivo models.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
title: Ð¡Ð¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¾Ð±ÑÐ»ÑÐ¶Ð¸Ð²Ð°Ð½Ð¸Ñ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð¸Ñ ÑÑÐ»ÑÐ³Ð°Ð¼Ð¸ Ð¿Ð°ÑÑÐ°Ð¶Ð¸ÑÑÐºÐ¾Ð³Ð¾ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ°
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐºÑÑÑÑÐ½ , ÐÐ³ÐµÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð³Ð¾ÑÐ¾Ð´ÑÐºÐ¾Ð¹ Ð¿Ð°ÑÑÐ°Ð¶Ð¸ÑÑÐºÐ¸Ð¹ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑ
ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ ÑÐ¸ÑÑÐµÐ¼Ð¾Ð¹ Ð¿Ð°ÑÑÐ°Ð¶Ð¸ÑÑÐºÐ¾Ð³Ð¾ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ°
Ð¿Ð¾ÑÑÐµÐ±Ð½Ð¾ÑÑÐ¸ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð¸Ñ Ð² ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½ÑÑ ÑÑÐ»ÑÐ³Ð°Ñ

description: ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ Ð³Ð¾ÑÐ¾Ð´ÑÐºÐ¾Ð³Ð¾ Ð¿Ð°ÑÑÐ°Ð¶Ð¸ÑÑÐºÐ¾Ð³Ð¾ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ° ÐºÑÑÐ¿Ð½Ð¾Ð³Ð¾ Ð³Ð¾ÑÐ¾Ð´Ð° (Ð³. ÐÑÐ°ÑÐ½Ð¾Ð´Ð°ÑÐ°). ÐÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐµ Ð¸ Ð¿ÑÐ¾ÑÑÑÐ°Ð½ÑÑÐ²ÐµÐ½Ð½ÑÐµ Ð² ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ð¸ ÑÐ¸ÑÑÐµÐ¼Ñ ÐÐÐ¢, ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ñ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÐ¸ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð´ÐµÐ¹ÑÑÐ²ÑÑÑÐµÐ¹ ÑÐ¸ÑÑÐµÐ¼Ñ ÐÐÐ¢, Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð½Ð¾Ð¹ Ð½Ð° ÑÐ°Ð±Ð¾ÑÐµ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ»ÐµÐºÑÑÐ¾ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ°. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾Ð³Ð¾ Ð¾Ð±ÑÐ»ÑÐ¶Ð¸Ð²Ð°Ð½Ð¸Ñ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð¸Ñ Ð³Ð¾ÑÐ¾Ð´Ð° Ð² ÑÑÐ»Ð¾Ð²Ð¸ÑÑ Ð¾ÑÑÑÑÑÑÐ²Ð¸Ñ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð°Ð»ÑÑÐµÑÐ½Ð°ÑÐ¸Ð²Ð½ÑÑ Ð½Ð°Ð·ÐµÐ¼Ð½Ð¾Ð¼Ñ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÑ Ð²Ð¸Ð´Ð¾Ð² ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ°. ÐÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ñ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐµ ÑÑÐ»Ð¾Ð²Ð¸Ñ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾Ð³Ð¾ ÑÐ¾Ð¾Ð±ÑÐµÐ½Ð¸Ñ Ð³Ð¾ÑÐ¾Ð´Ð° Ñ Ð¿ÑÐ¸Ð³Ð¾ÑÐ¾Ð´Ð°Ð¼Ð¸, Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð° Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼Ð¾ÑÑÑ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ Ð½Ð°Ð·ÐµÐ¼Ð½Ð¾Ð³Ð¾ Ð¼ÐµÑÑÐ¾ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¸Ð¼ÐµÑÑÐµÐ¹ÑÑ Ð¶ÐµÐ»ÐµÐ·Ð½Ð¾Ð´Ð¾ÑÐ¾Ð¶Ð½Ð¾Ð¹ Ð¸Ð½ÑÑÐ°ÑÑÑÑÐºÑÑÑÑ.
Human umbilical endothelial cells (HUVECs) and sex differences
Creators: name: Campesi, Ilaria
name: Addis, Roberta
name: Fois, Marco Angelo
name: Capobianco, Giampiero
name: Dessole, Salvatore
name: Fenu, Grazia
name: Cattaneo, Maria Grazia
name: Vicentini, Lucia M.
name: Franconi, Flavia
name: Montella, Andrea
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Sex differences; HUVECs; autophagy; birth weight.

description: HUVECs are worldwide used to study the endothelial physiology and pathology that might be involved in sex and gender differences detected at the cardiovascular level. The present work characterised the phenotype of HUVECs in terms of morphology, proliferative and migratory capacity and in the gene expression of oestrogen and androgen receptors and nitric oxide synthase 3 (NOS3) to evaluated if they are sexually dimorphic. Moreover, autophagic process was analysed in male and female HUVECs (MHUVECs and FHUVECs), as autophagy is influenced by sex. Umbilical cords were obtained from healthy, normal weight, male and female neonates born to healthy non-obese and non-smoking women. HUVECs morphology was analysed by electron microscopy, and their function was investigated by proliferation, viability, wound healing and chemotaxis assays. Real-time PCR was used to evaluate gene expression for oestrogen and androgen receptors and for NOS3, while the expression of the primary molecules involved in autophagic process [(Akt, the mammalian target of rapamycin (mTOR), beclin-1 and microtubule-associated protein 1 light chain 3 (LC3)] and NOS3 were analysed by western blotting. FHUVECs showed significantly higher proliferation and migration rate, and NOS3 mRNA and protein expression than MHUVECs. Conversely, beclin-1 and the LC3-II/LC3-I ratio were higher in MHUVECs than in FHUVECs, indicating a higher autophagy in male cells as also indicated by ultrastructural analysis showing a buildup of autophagic vacuoles at different stages in MHUVECs. The expression of oestrogen and androgen receptor genes, the protein expression of Akt, mTOR, and cellular size and shape were not influenced by sex. Male and female neonates did not differ in body weight, but the weight of male babies was positively associated with the weight of the mother, suggesting that the weight of the mother may exert a different influence on male and female babies. Our findings indicate that sex differences exist from prenatal life and are parameter- specific, suggesting that a better quality of the research on the endothelium in vitro can be obtained by analyzing HUVECs of both sexes as well as its translational value. Moreover, the sex differences observed in HUVECs could help the diseases of adulthood because endothelial dysfunction has a key role in cardiovascular diseases, diabetes mellitus, neurodegeneration and immune diseases.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Anthropometric evaluation in older individuals in relation to their physical activity level
Creators: name: Capranica, Laura
name: Condello, Giancarlo
name: Falbo, Simone
name: Tessitore, Antonio
name: Forte, Roberta
name: Pesce, Caterina
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Senior athletes; structured physical activity; anthropometrics.

description: Individuals older than 55 years tend to adopt sedentary lifestyles (European Commission, 2014) and unhealthy eating attitudes (Ahmed and Haboubi, 2010), which lead to an increase of body fat and risks of non-communicable diseases (Rosembloom and Bahnes, 2006; Sallinen et al., 2008). To investigate the association between the level of involvement in physical activity (PA) on anthropometric features with advancing age, height, body mass, waist (WC) and hip (HC) circumference, and triceps skinfold were measured in 20 athletes (training: >5 hr.week-1), 37 physically active (structured PA: 2 hr.week-1), and 42 sedentary (<1 hr.week-1), older individuals (55-84 yrs). Moreover body mass index (BMI), waist-hip (WHi) and waist-height (WHe) ratio, and fat arm index were calculated. A 2 (gender) x 3 (activity level) verified differences (p<0.05) between groups. No difference for gender emerged for BMI, HC, and WHi. Athletes showed lower (p<0.05) BMI, WC, HC, WHi, triceps skinfold, and arm fat index, and higher height values than physically active and sedentary counterparts. For body mass, a difference (p<0.05) emerged only between athletes with respect to sedentary counterpart. No differences emerged between physically active and sedentary groups. Findings indicate that in older ages only a high physical activity level allows controlling the anthropometric features, thus posing senior athletes at a lower risk of related non-communicable diseases.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Portal and interface chronic inflammation are associated with the progenitor cell compartment activation during NAFLD
Creators: name: Carotti, Simone
name: Vespasiani-Gentilucci, Umberto
name: Onetti-Muda, Andrea
name: Perrone, Giuseppe
name: Picardi, Antonio
name: Morini, Sergio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Portal inflammation; fibrosis; nonalcoholic fatty liver disease; hepatic progenitor cells.

description: Background and aim: During nonalcoholic fatty liver disease (NAFLD), portal and interface chronic inflammation (PCI and ICI) are strongly associated with fibrosis by activation of hepatic stellate cell (HSC)s (Brunt et al., 2009; Vespasiani-Gentilucci et al., 2014). However, the determinants of PCI and ICI observed in NAFLD remain to be elucidated. Since portal and periportal ductular reaction is related to disease progression, we aimed to investigate if PCI and ICI are associated with hepatic progenitor cell (HPC) compartment activation. Methods: Fifty-two NAFLD patients were studied. NAFLD activity score, fibrosis, PCI and ICI were histologically evaluated. HPCs, intermediate hepatobiliary cells and bile ductules/interlobular bile ducts were evaluated by immunohistochemistry for CK-7, CK-19 and EpCAM. HSC and myofibroblast (MF) activity were determined by immunohistochemistry for α-SMA. Results: PCI and ICI strongly correlated with HPC compartment activation and with the activity of MFs (p≤0.001). Lobular inflammation, ballooning and HPC compartment activation were all associated with both PCI (p<0.01) and ICI (p<0.05) by univariate analysis. In the multivariate models, HPC compartment activation was independently associated with PCI and ICI (OR 4.4, 1.7-11.5; OR 3.4, 1.5-7.9, respectively). Conclusions: During NAFLD, PCI and ICI are strongly associated with HPC compartment activation and this association is likely one determinant subtending the strong association between PCI/ICI and fibrosis.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014