cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
sj-docx-4-jop-10.1177_0269881120981392 – Supplemental material for Effects of omega-3 polyunsaturated fatty acids supplements on psychopathology and metabolic parameters in schizophrenia: A meta-analysis of randomized controlled trials
Creators: name: Kah K Goh
name: Chen, Cynthia Yi-An
name: Chun-Hsin Chen
name: Mong-Liang Lu
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)

description: Supplemental material, sj-docx-4-jop-10.1177_0269881120981392 for Effects of omega-3 polyunsaturated fatty acids supplements on psychopathology and metabolic parameters in schizophrenia: A meta-analysis of randomized controlled trials by Kah K Goh, Cynthia Yi-An Chen, Chun-Hsin Chen and Mong-Liang Lu in Journal of Psychopharmacology
In The Beginning Was The Mitochondrion
Creators: name: Kozlov, Stanislav
name: Bondarenko, Andrei
name: Evsyukov, Igor
name: Afonin, Alexei
Publisher: name: Zenodo
Year: 2016
Subjects: Alzheimer
Mitochondria
Aging
Autophagy
Amyloid

description: Here we propose a new theory about the cause of origin of Alzheimer's disease, taking into account recent progress in the field. Our hypothesis postulates the mitochondrial aging being the main cause of LOAD, and explains the connections between the cause and all the manifestations of the disease.
Genetic Epidemiology Of Ventricular Tachycardia In Patients With Cardiomyopathy In Kazakhstan: A Targeted Sequencing Study
Creators: name: Akilzhanova, Ainur
Publisher: name: Zenodo
Year: 2016
Subjects: cardiomyopathy
coronary heart disease
ventricular tachycardia
targeted NGS
96 gene panel

description: Ventricular tachycardia (VT) is a common complication in cardiac disorders of different etiology such as coronary heart disease (CHD) and cardiomyopathies. We hypothesized that the underlying molecular mechanism, independent of disease etiology, might originate from a common overlapping pattern of genetic variants in cardiac disease-related genes.  Aim: to investigate genetic basis of VT in patients with cardiomyopathy in Kazakhstan using targeted NGS (design of new HaloPlex gene panel).   Material and methods. Using a customized HaloPlex Target Enrichment System? (Agilent Technologies, USA) 96 cardiomyopathy associated candidate-genes were enriched and then sequenced on HiSeq2000 platform using 2x150bp paired-end standard sequencing conditions in DNA of 95 patients diagnosed with sporadic (64/95) or familial (26/95) cardiomyopathies (dilated cardiomyopathy (DCM): 37.3%, idiopathic ventricular tachycardia (iVT): 38.9%, CHD with severe episodes of VT: 24.2%, and others: 3%).   Results: The candidate gene library design covers a total target region of 463.767kbp with 406.062 analyzable target bases including all exonic and proximal intronic (+/-10bp) sequence and representing by 2,017 target loci. The mean coverage of all 95 samples at the target loci was 707.62-fold. Targeted sequencing and stepwise filtering of the annotated variants identified a total of 319 unique variants in 74 genes totaling up in 475 variants for the overall study group (HGMD listed). More than 50% of the patients carried at least two mutations, irrespective of the clinical phenotype. Furthermore, 215 private (unique) non-synonymous variants were observed in the patient cohort. Prediction scores of the private variants indicated high probability of disease association. Including the newly identified high-probability variants, each patient carried on average >4.8 genetic variants. Interestingly, statistical evaluation revealed no difference in the frequency of genetic variants (HGMD or rare variants) observed for the CHD and the DCM subgroup. The most abundant mutations of the CHD were observed in MYBPC3, DMD, LAMA2, MYH6 and GAA. PRKAG2 mutations were overrepresented in the CHD subgroup.  Conclusion: Our study indicates that the majority of the investigated patients with cardiomyopathies and VT, irrespective of disease phenotype or subgroup carry multiple disease-linked mutations and additional potentially functional rare variants in cardiac disease genes. We thus have to consider a molecular disease-overlap with converging phenotypes.
A 3D Tissue Culture Based High-Content Screening Platform That Uses Phenotypic Profiling To Discriminate Selective Inhibitors Of Tyrosine Kinases
Creators: name: Klop, Maarten
Publisher: name: Zenodo
Year: 2016
Subjects: RTK
high throughput
high content
image based
hit selection

description: 3D tissue cultures provide a more physiologically relevant context for the screening of compounds, compared to 2D cell cultures. Cells cultured in 3D hydrogels also show complex phenotypes, increasing the scope for phenotypic profiling.  Here we describe a high-content screening platform that uses invasive human prostate cancer cells cultured in 3D in standard 384-well assay plates to study the activity of potential therapeutic small molecules and antibody biologics. Image analysis tools were developed to process 3D image data to measure over 800 phenotypic parameters. Multiparametric analysis was used to evaluate the effect of compounds on tissue morphology.  We applied this screening platform to measure the activity and selectivity of inhibitors of the c-Met and EGF receptor (EGFR) tyrosine kinases in 3D cultured prostate carcinoma cells. c-Met and EGFR activity was quantified based on the phenotypic profiles induced by their respective ligands, HGF and EGF. The screening method was applied to a novel collection of 80 putative inhibitors of c-Met and EGFR. Compounds were identified that induced phenotypic profiles indicative of selective inhibition of either c-Met, EGFR or bispecific inhibition of both targets.  In conclusion, we describe a fully scalable high-content screening platform that uses phenotypic profiling to discriminate selective and non-selective (off-target) inhibitors in a physiologically relevant 3D cell culture setting.
sj-docx-5-jop-10.1177_0269881120981392 – Supplemental material for Effects of omega-3 polyunsaturated fatty acids supplements on psychopathology and metabolic parameters in schizophrenia: A meta-analysis of randomized controlled trials
Creators: name: Kah K Goh
name: Chen, Cynthia Yi-An
name: Chun-Hsin Chen
name: Mong-Liang Lu
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)

description: Supplemental material, sj-docx-5-jop-10.1177_0269881120981392 for Effects of omega-3 polyunsaturated fatty acids supplements on psychopathology and metabolic parameters in schizophrenia: A meta-analysis of randomized controlled trials by Kah K Goh, Cynthia Yi-An Chen, Chun-Hsin Chen and Mong-Liang Lu in Journal of Psychopharmacology
Additional file 1 of An exploratory case study of food sharing practices in Caribbean countries through a transition lens using intergenerational dyad interviews
Creators: name: Brugulat-Panés, Anna
name: Foley, Louise
name: Murphy, Madhuvanti M.
name: Unwin, Nigel
name: Guell, Cornelia
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Computational Biology

description: Supplementary Material 1
Additional file 1 of Rural research capacity: a co-created model for research success
Creators: name: Farris, Paige
name: Crist, Rachel
name: Miller, Sylvia
name: Shannon, Jackilen
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Appendices: Interview guide and ROCR system products.
Assessing Saudi women’s awareness about human papillomavirus (HPV) and their susceptibility to receive the vaccine
Creators: name: Alqarni, Sana S.
name: Alshehri, Samiyah M.
name: Alkhateeb, Mariam A.
name: Alsudias, Lama S.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Cervical cancer is a significant health concern for women worldwide, with human papillomavirus (HPV) being the primary cause. This study aimed to assess Saudi women’s awareness and knowledge of HPV, determine their information sources, and evaluate their intention to receive the HPV vaccine. A questionnaire-based survey was conducted among 654 Saudi females aged 18 to 60 years from January to May 2023. The results revealed that 60.85% of the participants had heard about HPV, but only 8.25% had received the HPV vaccination. Despite the low vaccination rate, 71.11% of the respondents expressed willingness to receive the vaccine. Educational level was the significant predictor of the vaccine awareness and acceptance. The internet and social media were the most prevalent sources of information about HPV. The study highlights the need for additional education about HPV-related diseases and vaccination among Saudi women. Although there is a high level of HPV vaccine acceptance, the lack of knowledge suggests that targeted educational interventions are necessary to increase awareness and promote vaccination uptake. These findings can inform public health strategies to reduce the burden of cervical cancer in Saudi Arabia through improved HPV vaccination coverage and education.
Thermal And Multiphase Validations With The Lattice Boltzmann Method Software Xflow
Creators: name: Ferran Pousa, Ángel
Publisher: name: Zenodo
Year: 2015
Subjects: Lattice Boltzmann Method, LBM, CFD, Computational Fluid Dynamics, Thermal, Multiphase

description: In this work a series of thermal and multiphase validation tests carried out with the CFD software XFlow is presented. Furthermore, a complete introduction to the lattice Boltzmann method, the numerical core of XFlow, is included.

The obtained numerical results show a mixed success, indicating a need for further enhancements in the implementation of the different numerical solvers involved.
Long-term follow up of patients treated with a DNA vaccine (pTVG-hp) for PSA-recurrent prostate cancer
Creators: name: Tonelli, Tommaso P.
name: Eickhoff, Jens C.
name: Johnson, Laura E.
name: Liu, Glenn
name: McNeel, Douglas G.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: We have previously reported two single-agent phase I trials, evaluating the dose or schedule, of a DNA vaccine (pTVG-HP) encoding prostatic acid phosphatase (PAP) administered with GM-CSF as the adjuvant. These were in patients with PSA-recurrent, radiographically non-metastatic, prostate cancer (PCa). We report here the long-term safety and overall survival of these patients. Specifically, 22 patients with non-metastatic, castration-sensitive PCa (nmCSPC) were treated with pTVG-HP, 100–1500 µg, administered over 12 weeks and followed for 15 y. 17 patients with non-metastatic castration-resistant PCa (nmCRPC) were treated with 100 µg pTVG-HP with different schedules of administration over 1 y and followed for 5 y. No adverse events were detected in long-term follow-up from either trial that were deemed possibly related to vaccination. Patients with nmCSPC had a median overall survival of 12.3 y, with 5/22 (23%) alive at 15 y. 8/22 (36%) died due to prostate cancer with a median survival of 11.0 y, and 9/22 (41%) died of other causes. Patients with nmCRPC had a median overall survival of 4.5 y, with 8/17 (47%) alive at 5 y. The presence of T-cells specific for the PAP target antigen was detectable in 6/10 (60%) individuals with nmCSPC, and 3/5 (60%) individuals with nmCRPC, many years after immunization. The detection of immune responses to the vaccine target years after immunization suggests durable immunity can be elicited in patients using a DNA vaccine encoding a tumor-associated antigen. Trial Registration: NCT00582140 and NCT00849121
E05677: Bede, in his Martyrology, records the feast on 24 November in Rome of *Chrysogonus (martyr of Aquileia, S00911). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

VIII Kl. Dec. Romae, natale sancti Chrysogoni, qui sub Diocletiano decollatus martyrium complevit. Scriptum in passione sanctae Anastasiae.

'24 November. At Rome, the feast of Saint Chrysogonus who, beheaded, completed his martyrdom under Diocletian. It is written in the Martyrdom of Saint Anastasia.'

Text: Quentin 1908, 58. Translation: Lifshitz 2000, 195, modified.
Additional file 1 of Effect of single-administration of d-sorbitol pretreatment on the bitterness and continued willingness to take asenapine: a randomized, single-blind, placebo-controlled, crossover trial
Creators: name: Wada, Shuhei
name: Iwamoto, Kunihiro
name: Okumura, Hiroki
name: Hida, Hirotake
name: Hiraoka, Shuichi
name: Kamei, Aya
name: Mori, Daisuke
name: Yamada, Kiyofumi
name: Ando, Masahiko
name: Ozaki, Norio
name: Ikeda, Masashi
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Cell Biology
Molecular Biology
Neuroscience
Pharmacology
Biological Sciences not elsewhere classified
Cancer
Science Policy
Mental Health

description: Additional file 1. Questionnaire survey content.
Additional file 2 of An exploratory case study of food sharing practices in Caribbean countries through a transition lens using intergenerational dyad interviews
Creators: name: Brugulat-Panés, Anna
name: Foley, Louise
name: Murphy, Madhuvanti M.
name: Unwin, Nigel
name: Guell, Cornelia
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Computational Biology

description: Supplementary Material 2
title: Thüringer Familien in Zeiten von Corona: Abschlussbericht zum Forschungsprojekt
Creators: name: Lochner, Barbara
Publisher: name: Fachhochschule Erfurt
Year: 2021
Subjects: subject: COVID-19
subject: Familie
subject: Hausunterricht
subject: Tagesbetreuung
subject: 300

description: Als eines der ersten Forschungsprojekte deutschlandweit hat die Studie „Thüringer Familien in Zeiten von Corona“ sich der Situation von Kindern, Eltern und Familien gewidmet. Als Kooperationsprojekt der Fachhochschule Erfurt und des Deutschen Kinderschutzbundes Landesverband Thüringen e.V., unterstützt vom Thüringer Ministerium für Wirtschaft, Wissenschaft und Digitale Gesellschaft (TMWWDG), wurde vom 01. bis 12.04.2020 eine quantitative Online-Befragung durchgeführt, an der sich mehr als 3.000 Personen beteiligt haben. Im Herbst, kurz bevor erneut Einschränkungen in Kraft traten, wurden auf Basis der Auswertungen dieser Daten vom 19.10. bis 12.11.2020 qualitative Telefoninterviews mit neun Personen durchgeführt, um familiäre Deutungs- und Handlungsweisen im Umgang mit den pandemiebedingten Herausforderungen differenzierter zu erfassen. Der Bericht fasst die zentralen Ergebnisse der Studie zusammen
sj-pdf-1-hol-10.1177_0959683621994641 – Supplemental material for Ancient to recent-past runoff harvesting agriculture in the hyper-arid Arava Valley: OSL dating and insights
Creators: name: Stavi, Ilan
name: Gidon Ragolsky
name: Haiman, Mordechai
name: Porat, Naomi
Publisher: name: SAGE Journals
Year: 2021
Subjects: Geography
History

description: Supplemental material, sj-pdf-1-hol-10.1177_0959683621994641 for Ancient to recent-past runoff harvesting agriculture in the hyper-arid Arava Valley: OSL dating and insights by Ilan Stavi, Gidon Ragolsky, Mordechai Haiman and Naomi Porat in The Holocene
E05678: Bede, in his Martyrology, records the feast on 24 November of *Crescentianus, companion of Cyriacus (here 'Caesarius'), Smaragdus and Largus (martyrs of Rome, S00678). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

VIII Kl. Dec. Ipso die natale sancti Crescentiani, qui erat cum Caesario diacano et Largo et Smaragdo in carcere, sub persecutione Maximini filii Maximiani, et eductus iubente Carpasio vicario de carcere, suspensus est in equuleum et fustibus caesus atque unguibus rasus, diutius deinde flammis circum latera eius appositis, diu ustulatus, emisit spiritum, et ab Iohanne presbytero sepultus est in coemeterio Priscillae. Ipso tempore Maximinus interfecit sororem suam Artemiam. Scriptum in gestis Marcelli papae.

'24 November. On that same day, the feast of Saint Crescentianus, who was with deacon Caesarius [sic] and Largus and Smaragdus in prison, under the persecution of Maximinus son of Maximianus, and, having been led out from prison on the command of the vicarius Carpasius, was hung up on the rack and beaten with clubs and scraped with nails and then, once flames had been for a long time applied around his sides, having been scorched for a long time, sent forth his spirit, and was buried by the priest Iohannes in the cemetery of Priscilla. At the same time Maximinus killed his sister Artemia. It is written in the deeds of Pope Marcellus.'

Text: Quentin 1908, 84-5. Translation: Lifshitz 2000, 195, lightly modified.
Supplemental Material, sj-pdf-1-mrj-10.1177_0022243720977830 - Consumer Rational (In)Attention to Favorable and Unfavorable Product Information, and Firm Information Design
Creators: name: Kinshuk Jerath
name: Qitian Ren
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150402 Hospitality Management
subject: FOS: Economics and business

description: Supplemental Material, sj-pdf-1-mrj-10.1177_0022243720977830 for Consumer Rational (In)Attention to Favorable and Unfavorable Product Information, and Firm Information Design by Kinshuk Jerath and Qitian Ren in Journal of Marketing Research
Additional file 3 of An exploratory case study of food sharing practices in Caribbean countries through a transition lens using intergenerational dyad interviews
Creators: name: Brugulat-Panés, Anna
name: Foley, Louise
name: Murphy, Madhuvanti M.
name: Unwin, Nigel
name: Guell, Cornelia
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Computational Biology

description: Supplementary Material 3
Surveillance for adverse events following immunization in Hebei Province, China, 2018-2020
Creators: name: Sun, Li
name: Wang, Shifan
name: Wang, Yafei
name: Wang, Yihan
name: Wang, Jinghui
name: Li, Jing
name: Xu, Xiaomeng
name: Zhang, Junmian
name: Cong, Yanli
name: Guo, Yu
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: The aim of this study was to analyze the incidence and characteristics of adverse events following immunization (AEFI) with post-licensure vaccines used in Hebei province from 2018 to 2020 and to evaluate the safety of vaccines. All information of AEFI was gained from national adverse event following immunization surveillance system (NAEFISS) in Hebei Province from 2018 to 2020. Descriptive epidemiology method was used to analyze the data about AEFI in Hebei province. Reporting rates of AEFI were calculated by sex, age, city, categories of AEFI, severity of AEFI, reaction categories, etc. A total of 35,999 AEFI were reported through NAEFISS, and the average annual rate was 47.64/100,000 doses. The reporting rates of common adverse reactions and rare adverse reactions were 46.37/100,000 doses and 1.05/100,000 doses. The male-to-female ratio was 1.26:1. Most of the AEFI were concentrated in the ≤1 year age group and were reported in the second quarter and third quarter. The majority of AEFI were reported to be recovered or improved, and about 62% of the AEFI occurred within 24 hours after vaccination. Vaccines associated with the highest reporting rate of AEFI were diphtheria, tetanus and acellular pertussis combined vaccine (DTaP, 170.45/100,000 doses). The reporting rate of allergic rash was found to be the highest in the adverse reactions (0.29/100,000 doses). The majority of AEFI cases were common adverse reactions, while serious rare adverse reactions caused by vaccines were extremely uncommon, and all vaccines used in Hebei Province were safe.
Additional file 1 of Patellar instability-induced bone loss in the femoral trochlea is associated with the activation of the JAK1/STAT3 signaling pathway in growing mice
Creators: name: Ma, Chen
name: Kou, Wenguan
name: Cui, Zhaoxia
name: Liu, Wenfeng
name: Liu, Changli
name: Wang, Shengjie
name: Wang, Fei
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Ecology
subject: Developmental Biology
subject: Hematology

description: Additional file 1. Fig. S1a: The original blots/gels of JAK1, The figure in the munuscript was cropped from the first one. The red circle on the left corresponded to the red circle on the right. Fig. S1b: The original blots/gels of STAT3, The figure in the munuscript was cropped from the first one. The red circle on the left corresponded to the red circle on the right. Fig. S1c: The original blots/gels of OPG, The figure in the munuscript was cropped from the first one. The red circle on the left corresponded to the red circle on the right. Fig. S1d: The original blots/gels of RANKL, The figure in the munuscript was cropped from the first one. The red circle on the left corresponded to the red circle on the right. Fig. S1e: The original blots/gels of ACTIN, The figure in the munuscript was cropped from the first one. The red circle on the left corresponded to the red circle on the right.
sj-pdf-1-aan-10.1177_0218492321997077 - Supplemental material for Survival benefit from a second arterial conduit to the circumflex circulation persists in elderly after coronary artery bypass surgery
Creators: name: Suvitesh Luthra
name: Leiva-Juárez, Miguel M
name: Malvindi, Pietro G
name: Billing, John S
name: Ohri, Sunil K
Publisher: name: SAGE Journals
Year: 2021
Subjects: Cardiology

description: Supplemental material, sj-pdf-1-aan-10.1177_0218492321997077 for Survival benefit from a second arterial conduit to the circumflex circulation persists in elderly after coronary artery bypass surgery by Suvitesh Luthra, Miguel M Leiva-Juárez Pietro G Malvindi, John S Billing and Sunil K Ohri in Asian Cardiovascular & Thoracic Annals
E05679: Bede, in his Martyrology, records the feast on 25 November of *Petros (bishop and martyr of Alexandria, S00247). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

VII Kl. Dec. Natale sancti Petri episcopi Alexandrini: qui cum esset omnibus adornatus virtutibus, in Scripturis quoque divinis nullius priorum inferior, vere sacerdos et hostia Dei, subito rapitur atque Maximini praecepto capite obtruncatur: cum quo simul et alii plures ex Aegypto episcopi trucidantur. Scriptum in Historia Ecclesiastica, libro nono.

'25 November. The feast of Saint Petros, bishop of Alexandria: who, when he was adorned with all the virtues, and inferior to none of his predecessors in divine Scripture, a true priest and host of God, was suddenly seized and had his head cut off at the command of Maximinus: and with him, very many other bishops from Egypt were likewise butchered. It is written in the Ecclesiastical History [of Eusebius], book nine.'

Text: Quentin 1908, 99. Translation: Lifshitz 2000, 195, modified.
sj-pdf-3-hss-10.1177_1556331620979653 – Supplemental material for The Role of Telehealth in Sideline Management of Sports-Related Injuries
Creators: name: Taylor, Samuel A.
name: Lamplot, Joseph D.
name: Subramanyam, Venkat
name: Day, Molly A.
name: Kinderknecht, James J.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-3-hss-10.1177_1556331620979653 for The Role of Telehealth in Sideline Management of Sports-Related Injuries by Samuel A. Taylor, Joseph D. Lamplot, Venkat Subramanyam, Molly A. Day and James J. Kinderknecht in HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery
Booster vaccines dose reduced mortality in hospitalized COVID-19 patients requiring oxygen supplementation: Evidence from the Beijing Omicron outbreak
Creators: name: Wang, Xinrui
name: Zhang, Yi
name: Huang, Chong
name: Yang, Hui
name: Jiang, Chunguo
name: Yu, Xiaojia
name: Zhao, Rui
name: Hong, Jun
name: Wang, Yushu
name: An, Zhuoling
name: Tong, Zhaohui
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: To assess the impact of vaccines on clinical outcomes among hospitalized COVID-19-infected patients requiring oxygen supplementation during the Beijing Omicron outbreak. We conducted a retrospective cohort study at Beijing Chaoyang Hospital, Capital Medical University, from November 15, 2022, to March 31, 2023. Vaccination statuses were categorized into 3 doses, 2 doses, and unvaccinated (0 dose). The primary outcome was 28-day all-cause mortality. Secondary outcomes included poor outcomes, intensive care unit admission, cardiovascular thromboembolism events, and hospital readmission. Among the included patients, 117 were 2 doses, 285 received booster doses, and 503 were unvaccinated. After propensity score inverse probability weighting, the 3 doses group showed a significantly lower 28-day all-cause mortality compared to the unvaccinated group (inverse probability of treatment weighting-adjusted HR: 0.64, 95% CI: 0.50–0.81). No significant difference was observed in all-cause mortality between the 2 doses and unvaccinated groups. No significant differences were observed in secondary outcome analyses when comparing the 3 doses or 2 doses group to the unvaccinated group. Subgroup analysis revealed significant benefits of booster vaccination in patients with shorter symptom duration, lower Charlson Comorbidity Index, and without immunosuppression status. Our study highlights the significant reduction in all-cause mortality among hospitalized Omicron-infected patients who received a third dose vaccine. These findings underscore the importance of prioritizing booster vaccinations, especially among the elderly. Further research is warranted to confirm and extend these observations.
E05680: Bede, in his Martyrology, records the feast on 29 November at Rome of *Saturninus (martyr of Rome, buried on the via Salaria, S00422), 'Sennes' (a misreading of senex), and *Sisinnius (deacon and martyr of Rome, S02058), who caused *Papias and Maurus (soldiers and martyrs of Rome, S02057) to believe. Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

III Kl. Dec. Romae, sancti Saturnini martyris et Sennes et Sisinnii diaconi sub Maximiano, a quo primo inter alio damnati ad fodiendam arenam, ad faciendas thermas diocletianas, deinde in carcere diu sunt macerati, ubi multos gentiles docentes baptizabant: et denuo educti, vincti catenis et nudis pedibus ante praefectum Urbis Laodicium iussi sunt in equuleo levari et attrahi nervis, et fustibus ac scorpionibus caedi: quibus etiam postmodum flammas ad latera iussit apponi et depositos de equuleo capite truncari. Quorum corpora cum Iohanne presbtero colligens Thrason vir christianissimus, qui de facultatibus suis martyribus multa ministraverat, sepelivit in praedio suo, via Salaria. His in medio certamine positis, crediderunt duo milites Papias et Maurus, qui mox comprehensi a Laodicio, et non multo post martyrio coronati sunt. Scriptum in gestis Marcelli papae.

'29 November. At Rome, [the feast] of Saints Saturninus, martyr, and Sennes [should read: 'Saturninus, martyr and old man'], and Sisinnius, deacon, under Maximianus, by whom they, among others, were first condemned to dig sand, in order to build the Baths of Diocletian, then having wasted away for a long time in prison where, teaching, they kept baptising many Gentiles: and having been led back out again, bound with chains and barefooted, before Laodicius prefect of the city, they were ordered to be lifted up onto the rack and drawn tight with fetters, and beaten with clubs and 'scorpions': after this he also ordered flames to be applied to their sides and for their heads to be cut off once they had been removed from the rack. A most Christian man, Thraso, who has been ministering much to the martyrs out of his own resources, collecting the bodies along with Iohannes, a priest, buried them on his own estate on the via Salaria. While [the martyrs] were still in the midst of their struggle, two soldiers, Papias and Maurus, believed; they were soon apprehended by Laodicius, and not long afterward were crowned with martyrdom. It is written in the deeds of Pope Marcellus.'

Text: Quentin 1908, 82-3. Translation: Lifshitz 2000, 195-6, modified.
Additional file 1 of Chitosan oligosaccharide decorated liposomes combined with TH302 for photodynamic therapy in triple negative breast cancer
Creators: name: Ding, Yinan
name: Yang, Rui
name: Yu, Weiping
name: Hu, Chunmei
name: Zhang, Zhiyuan
name: Liu, Dongfang
name: An, Yanli
name: Wang, Xihui
name: He, Chen
name: Liu, Peidang
name: Tang, Qiusha
name: Chen, Daozhen
Publisher: name: figshare
Year: 2021
Subjects: Biochemistry
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer

description: Additional file 1: Figure S1. The TLC results of OA-HNS and CO-OA. (A) TLC results of OA-NHS. (B) TLC results of CO-OA. Figure S2. HPLC–MS analysis of HPPH lipid. Figure S3. The surface potentials of HPPH-TH302/Lipo and CO-HPPH-TH302/Lipo. (A) Zeta potential of HPPH-TH302/Lipo; (B) Zeta potential of CO-HPPH-TH302/Lipo; (C) Zeta potentials of HPPH-TH302/Lipo and CO-HPPH-TH302/Lipo, each bar represents the mean ± SD of five replicates. Figure S4. Singlet oxygen production before 660 nm irradiation was measured by electron spin resonance (ESR). (A) Liposome group; (B) CO-Liposome; (C) TH302/Lipo; (D) CO-TH302/Liposome; (E) HPPH/Lipo; (F) CO-HPPH/Lipo; (G) HPPH-TH302/Lipo; (H) CO-HPPH-TH302/Lipo. Figure S5. Singlet oxygen production after 660 nm irradiation was measured by electron spin resonance (ESR). (A) Liposome group; (B) CO-Liposome; (C) TH302/Lipo; (D) CO-TH302/Liposome; (E) HPPH/Lipo; (F) CO-HPPH/Lipo; (G) HPPH-TH302/Lipo; (H) CO-HPPH-TH302/Lipo. Figure S6. The fluorescence signal between targeted and non-targeted liposomes detected by flow cytometry. Flow cytometric analysis of FITC positive MDA-MB-231 cells: (i) Control group: free-MDA-MB-231 cells; (ii) CO-Lipo group: liposomes with CO co-incubation with MDA-MB-231 cells; (iii) Lipo group: liposomes without CO co-incubation with MDA-MB-231 cells; (iv) Blocked CO-Lipo group: liposomes with CO co-incubation with CD44-preblocked MDA-MB-231 cells. Figure S7. The cytotoxicity of various liposomes without HPPH that illuminated by 660 nm LED in vitro. (A) Inhibition of viability of MDA-MB-231 cells; (B) Inhibition of viability of MCF-7 cells, each bar represents the mean ± SD of five replicates.
Monitoring the safety of the adjuvanted human papillomavirus vaccine, HPV-16/18-AS04: Protocol for a cohort study using electronic health records in Yinzhou, China
Creators: name: Yang, Junting
name: Welby, Sarah
name: Liu, Zhike
name: Deng, Siwei
name: Liu, Guangxu
name: Meng, Ruogu
name: Yang, Yu
name: Sun, Yixin
name: He, Yunkun
name: Jiang, Ning
name: Wu, Zhenhua
name: Liu, Keruo
name: Rosillon, Dominique
name: Cohet, Catherine
name: Zhan, Siyan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: This protocol was developed to conduct population-wide surveillance of the bivalent HPV-16/18-AS04-adjuvanted human papillomavirus (HPV) vaccine in terms of uptake and safety outcomes including potential immune-mediated diseases (pIMDs) and pregnancy-related outcomes in China. The study will use electronic health records from 2010 to 2020 from the Yinzhou Regional Health Information Platform and include a population-based cohort of female permanent residents aged 9–45 years. Baseline and follow-up periods will be defined according to the 2017 introduction of HPV-16/18-AS04 in China. Patients with pIMDs and pregnancy-related outcomes will be identified using primary diagnostic codes from outpatient and inpatient electronic health records. A time trend analysis will be performed to describe the incidence of pIMDs and pregnancy-related outcomes during baseline and follow-up periods by age and overall, per calendar year. Depending on the number of safety outcomes and the size of the study population, incidence in vaccinated and unvaccinated cohorts will be compared using a Poisson regression model for pIMDs and a logistic regression model for pregnancy-related outcomes, adjusting for age and calendar year. Methods and findings from this study will provide valuable experience for designing future real-world studies and complement observations made during clinical trials and post-marketing studies. Study registration: http://www.chinadrugtrials.org.cn/index.html: CTR20210523.
Additional file 1 of An in-depth analysis of perinatal related mortality among women of South Asian ethnicity in Aotearoa New Zealand
Creators: name: de Graaff, Esti
name: Sadler, Lynn
name: Lakhdhir, Heena
name: Simon-Kumar, Rachel
name: Peiris-John, Roshini
name: Burgess, Wendy
name: Okesene-Gafa, Karaponi
name: Cronin, Robin
name: McCowan, Lesley
name: Anderson, Ngaire
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1. Background to the datasets in this study.
Superfluidity in neutrino clusters
Creators: name: Dvornikov, Maxim
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study the formation of a superfluid condensate of neutrinos inside a neutrino cluster. The attractive interaction between neutrinos is mediated by a scalar boson which is lighter than a neutrino. We consider the appearance of neutrino bound states consisting of particles with oppositely directed spins. The gap equation for such a system is derived. Based on numerical simulations of the neutrino distribution in a cluster, we find the phase transition temperature and the coherence length inside such a cluster for various parameters of the system. The constraints on the parameters of the Yukawa interaction, resulting in the neutrino superfluidity, are derived. We obtain that the cosmic neutrino background can contribute to the superfluid condensate inside a neutrino cluster having realistic characteristics. The mechanism of the neutrino cluster cooling in the early universe, based on the plasmons Čerenkov radiation, is proposed.
description: 14 pages in LaTeX2e, 9 eps figures
Parental knowledge on the respiratory syncytial virus before the nirsevimab immunization program: Attitudes toward immunization in an autonomous community of Spain
Creators: name: Moreno, Matilde Zornoza
name: Martín, Jaime Jesús Pérez
name: Moreno, Mª Cruz Gómez
name: Abellán, Mª Pilar Ros
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in young children and associated with most bronchiolitis- and pneumonia-related hospitalizations. A new preventive monoclonal antibody (MAb), nirsevimab, has been launched in the United States, Luxembourg, and France, and was recently approved to be given in a population-based manner throughout Spain. This study aimed to have a first pre-immunization insight into the Spanish parental knowledge about bronchiolitis, RSV, and nirsevimab immunization. Parents in Murcia with children <2 years of age up to the date of September 1, 2023, were selected to complete a questionnaire. The primary endpoint was the parental knowledge about bronchiolitis, RSV, and nirsevimab. A total of 3,217 responses were analyzed. The majority (95.8%) were aware of bronchiolitis. Meanwhile, 46.6% of the respondents knew about RSV, most of them only after the first child’s birth. Information about RSV or bronchiolitis was mainly obtained from family members, with only 4.8% reporting having been informed by Health care Professionals (HCPs). Only 11.2% of respondents were aware of nirsevimab. Nonetheless, these were not entirely satisfied with the information received (score of 3.3 out of 5) and shared that HCPs should be the primary source of information. The present survey then highlights the need for better and more efficient educational strategies directed to all parents/legal guardians. It also sheds some light on the different factors that should be considered to improve awareness of RSV immunization to decrease its burden in Spain and beyond.
Machine Learning Clifford invariants of ADE Coxeter elements
Creators: name: Chen, Siqi
name: Dechant, Pierre-Philippe
name: He, Yang-Hui
name: Heyes, Elli
name: Hirst, Edward
name: Riabchenko, Dmitrii
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Group Theory (math.GR)
subject: Representation Theory (math.RT)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: There has been recent interest in novel Clifford geometric invariants of linear transformations. This motivates the investigation of such invariants for a certain type of geometric transformation of interest in the context of root systems, reflection groups, Lie groups and Lie algebras: the Coxeter transformations. We perform exhaustive calculations of all Coxeter transformations for $A_8$, $D_8$ and $E_8$ for a choice of basis of simple roots and compute their invariants, using high-performance computing. This computational algebra paradigm generates a dataset that can then be mined using techniques from data science such as supervised and unsupervised machine learning. In this paper we focus on neural network classification and principal component analysis. Since the output -- the invariants -- is fully determined by the choice of simple roots and the permutation order of the corresponding reflections in the Coxeter element, we expect huge degeneracy in the mapping. This provides the perfect setup for machine learning, and indeed we see that the datasets can be machine learned to very high accuracy. This paper is a pump-priming study in experimental mathematics using Clifford algebras, showing that such Clifford algebraic datasets are amenable to machine learning, and shedding light on relationships between these novel and other well-known geometric invariants and also giving rise to analytic results.
description: v1: 34 pages, 16 Figures, 12 Tables. v2: Typos corrected and some comments added. Matches the author-accepted version for publication in Advances in Applied Clifford Algebras
sj-pdf-3-jrs-10.1177_0141076821992453 - Supplemental material for The potential effectiveness of the WHO International Health Regulations capacity requirements on control of the COVID-19 pandemic: a cross-sectional study of 114 countries
Creators: name: Wong, Martin CS
name: Junjie Huang
name: Wong, Sunny H
name: Teoh, Jeremy Yuen-Chun
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental material, sj-pdf-3-jrs-10.1177_0141076821992453 for The potential effectiveness of the WHO International Health Regulations capacity requirements on control of the COVID-19 pandemic: a cross-sectional study of 114 countries by Martin CS Wong, Junjie Huang, Sunny H Wong and Jeremy Yuen-Chun Teoh in Journal of the Royal Society of Medicine
E05681: Bede, in his Martyrology, records the feast on 10 December in Barcelona of *Eulalia (virgin and martyr of Barcelona, S02047). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

IV Id. Dec. Natale sanctae Eulaliae virginis, in Barcelona, civitate Hispaniae, sub Daciano praeside, quae cum esset tredecim annorum, post plurima tormenta decollata est; et resilente an ea capite, columba de corpore eius exire visa est.

'10 December. In Barcelona, a city in Spain, under the ruler Dacian, the feast of Saint Eulalia, virgin: who, when she was thirteen years old, after many torments, was beheaded; and as her head was springing away from her, a dove was seen to leave her body.'

Text: Quentin 1908, 71. Translation: Lifshitz 2000, 196, lightly modified.
A Prototype-Based Neural Network for Image Anomaly Detection and Localization
Creators: name: Huang, Chao
name: Kang, Zhao
name: Wu, Hong
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Image anomaly detection and localization perform not only image-level anomaly classification but also locate pixel-level anomaly regions. Recently, it has received much research attention due to its wide application in various fields. This paper proposes ProtoAD, a prototype-based neural network for image anomaly detection and localization. First, the patch features of normal images are extracted by a deep network pre-trained on nature images. Then, the prototypes of the normal patch features are learned by non-parametric clustering. Finally, we construct an image anomaly localization network (ProtoAD) by appending the feature extraction network with $L2$ feature normalization, a $1\times1$ convolutional layer, a channel max-pooling, and a subtraction operation. We use the prototypes as the kernels of the $1\times1$ convolutional layer; therefore, our neural network does not need a training phase and can conduct anomaly detection and localization in an end-to-end manner. Extensive experiments on two challenging industrial anomaly detection datasets, MVTec AD and BTAD, demonstrate that ProtoAD achieves competitive performance compared to the state-of-the-art methods with a higher inference speed. The source code is available at: https://github.com/98chao/ProtoAD.
description: Published in Neural Processing Letters 2024
Economic burden of respiratory syncytial virus disease in Latin America: A systematic review
Creators: name: Moreno, Carolina
name: Bardach, Ariel
name: Palermo, María Carolina
name: Sandoval, María Macarena
name: Baumeister, Elsa
name: Ruvinsky, Silvina
name: Ulloa-Gutiérrez, Rolando
name: Stegelmann, Katharina
name: Ruesjas, Sofía Ardiles
name: LaRotta, Jorge
name: de Almeida, Rodrigo Sini
name: Ciapponi, Agustín
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: This Systematic Review assesses the economic impact of Respiratory Syncytial Virus (RSV) in Latin America and the Caribbean (LAC) in relation to healthcare resource utilization and associated costs. We searched online databases from January 2012 to November 2022 to identify eligible publications. We identified 12 publications that reported direct costs, indirect costs, and resources associated with RSV and its complications. The primary direct medical resources reported were medical services, diagnostics tests and procedures, and length of stay (LOS). Direct total costs per patient ranged widely from $563 to $19,076. Direct costs are, on average, 98% higher than indirect costs. Brazil reported a higher total cost per patient than Colombia, El Salvador, México, Panamá, and Puerto Rico, while for indirect costs per patient, El Salvador and Panamá had higher costs than Brazil, Colombia, and Mexico. The mean LOS in the general ward due to RSV was 6.9 days (range 4 to 20 days) and the mean Intensive Care Unit LOS was 9.1 days (range 4 to 16 days). In many countries of the LAC region, RSV represents a considerable economic burden on health systems, but significant evidence gaps were identified in the region. More rigorous health economic studies are essential to better understand this burden and to promote effective healthcare through an informed decision-making process. Vaccination against RSV plays a critical role in mitigating this burden and should be a priority in public health strategies.
E05682: Venantius Fortunatus, in a poem to Eufronius, bishop of Tours (north-west Gaul), advises him to take as a model his predecessor *Martin (ascetic and bishop of Tours, ob. 397, S00050). Poem 3.3, written in Latin in Gaul, 565/573.
Creators: name: Kwojtalik
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Venantius Fortunatus, Poems 3.3 (Ad eundem = Ad Eufronium episcopum Turonensem, 'To the same person' [Eufronius, bishop of Tours]), 23-26

Extract:

Martinus meritis hac vos in sede locavit;
 dignus eras heres qui sua iussa colis.
Ille tenet caelum, largo dans omnia voto; 25
 iunctus eris Christo hunc imitando virum.

'Martin by his merits settled you in this see; you were a worthy heir, who put into practice his precepts. He occupies heaven, granting all favors with generous intent; you will join Christ’s company by taking this man as model.'

Text: Leo 1881, 51. Translation: Roberts 2017, 131.
Additional file 1 of The impact of hypercortisolism beyond metabolic syndrome on left ventricular performance: a myocardial work analysis
Creators: name: Sahiti, Floran
name: Detomas, Mario
name: Cejka, Vladimir
name: Hoffmann, Kristina
name: Gelbrich, Götz
name: Frantz, Stefan
name: Kroiss, Mathias
name: Heuschmann, Peter U.
name: Hahner, Stefanie
name: Fassnacht, Martin
name: Deutschbein, Timo
name: Störk, Stefan
name: Morbach, Caroline
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Mathematical Sciences not elsewhere classified
subject: Mental Health

description: Supplementary Material 1