cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A Melanocortin-4 Receptor Agonist Induces Skin and Hair Pigmentation in Patients with Monogenic Mutations in the Leptin-Melanocortin Pathway
Creators: name: Kanti, Varvara
name: Puder, Lia
name: Jahnke, Irina
name: Krabusch, Philipp Maximilian
name: Kottner, Jan
name: Vogt, Annika
name: Richter, Claudia
name: Andruck, Annette
name: Lechner, Lara
name: Poitou, Christine
name: Krude, Heiko
name: Gottesdiener, Keith
name: Clément, Karine
name: Farooqi, Ismaa Sadaf
name: Wiegand, Susanna
name: Kühnen, Peter
name: Blume-Peytavi, Ulrike
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: Proopiomelanocortin
subject: Leptin receptor
subject: Melanocortin-4 receptor agonist
subject: Hyperpigmentation
subject: Melanocortin-1 receptor
subject: Leptin-melanocortin pathway
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background and Objectives: Gene mutations within the leptin-melanocortin signaling pathway lead to severe early-onset obesity. Recently, a phase 2 trial evaluated new pharmacological treatment options with the MC4R agonist setmelanotide in patients with mutations in the genes encoding proopiomelanocortin (POMC) and leptin receptor (LEPR). During treatment with setmelanotide, changes in skin pigmentation were observed, probably due to off-target effects on the closely related melanocortin 1 receptor (MC1R). Here, we describe in detail the findings of dermatological examinations and measurements of skin pigmentation during this treatment over time and discuss the impact of these changes on patient safety. Methods: In an investigator-initiated, phase 2, open-label pilot study, 2 patients with loss-of-function POMC gene mutations and 3 patients with loss-of-function variants in LEPR were treated with the MC4R agonist setmelanotide. Dermatological examination, dermoscopy, whole body photographic documentation, and spectrophotometric measurements were performed at screening visit and approximately every 3 months during the course of the study. Results: We report the results of a maximum treatment duration of 46 months. Skin pigmentation increased in all treated patients, as confirmed by spectrophotometry. During continuous treatment, the current results indicate that elevated tanning intensity levels may stabilize over time. Lips and nevi also darkened. In red-haired study participants, hair color changed to brown after initiation of setmelanotide treatment. Discussion: Setmelanotide treatment leads to skin tanning and occasionally hair color darkening in both POMC- and LEPR-deficient patients. No malignant skin changes were observed in the patients of this study. However, the results highlight the importance of regular skin examinations before and during MC4R agonist treatment.
The impact of soil moisture variation on the vehicle loading of reinforced concrete box culverts
Creators: name: Packianathan, Santaseelan.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Metallic coplanar resonators optimized for low-temperature measurements
Creators: name: Rahim, Mojtaba Javaheri
name: Lehleiter, Thomas
name: Bothner, Daniel
name: Krellner, Cornelius
name: Koelle, Dieter
name: Kleiner, Reinhold
name: Dressel, Martin
name: Scheffler, Marc
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Metallic coplanar microwave resonators are widely employed at room temperature, but their low-temperature performance has received little attention so far. We characterize compact copper coplanar resonators with multiple modes from 2.5 to 20 GHz at temperatures as low as 5 K. We investigate the influence of center conductor width (20 to 100 μm) and coupling gap size (10 to 50 μm), and we observe a strong increase of quality factor (Q) for wider center conductors, reaching values up to 470. The magnetic-field dependence of the resonators is weak, with a maximum change in Q of 3.5% for an applied field of 7 T. This makes these metallic resonators well suitable for magnetic resonance studies, as we document with electron spin resonance (ESR) measurements at multiple resonance frequencies.
description: 6 pages, 5 figures
DIREITOS FUNDAMENTAIS: SUAS DIMENSÕES
Creators: name: Santos, Daniele Cristina Palma
name: Simeão, Álvaro Osório Do Valle
Publisher: name: figshare
Year: 2020
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: Sociology
subject: FOS: Sociology

description: Os direitos fundamentais são direitos autorais e direitos básicos, nenhum caractere inviolável, intemporal e universal , e por isso são considerados como pilares da Constituição Federal de 1988. Assim, diante da importância desse tema ou o presente trabalho tem como objetivo apresentar um estudo sobre os direitos fundamentais, seus conceitos, o pensamento de Norberto Bobbio, suas dimensões e por fim os constitucionalismos.
The “Flying Intervention Team”: A Novel Stroke Care Concept for Rural Areas
Creators: name: Hubert, Gordian Jan
name: Kraus, Frank
name: Maegerlein, Christian
name: Platen, Sabine
name: Friedrich, Benjamin
name: Kain, Hans-Ulrich
name: Witton-Davies, Thomas
name: Hubert, Nikolai Dominik
name: Zimmer, Claus
name: Bath, Philip M.
name: Audebert, Heinrich J.
name: Haberl, Roman L.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: Ischemic stroke
subject: Thrombectomy
subject: Telemedicine
subject: Health care concept
subject: Helicopter
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Endovascular treatment of large vessel occlusion in acute ischemic stroke patients is difficult to establish in remote areas, and time dependency of treatment effect increases the urge to develop health care concepts for this population. Summary: Current strategies include direct transportation of patients to a comprehensive stroke center (CSC) ("mothership model") or transportation to the nearest primary stroke center (PSC) and secondary transfer to the CSC ("drip-and-ship model"). Both have disadvantages. We propose the model "flying intervention team." Patients will be transported to the nearest PSC; if telemedically identified as eligible for thrombectomy, an intervention team will be acutely transported via helicopter to the PSC and endovascular treatment will be performed on site. Patients stay at the PSC for further stroke unit care. This model was implemented at a telestroke network in Germany. Fifteen remote hospitals participated in the project, covering 14,000 km(2) and a population of 2 million. All have well established telemedically supported stroke units, an angiography suite, and a helicopter pad. Processes were defined individually for each hospital and training sessions were implemented for all stroke teams. An exclusive project helicopter was installed to be available from 8 a.m. to 10 p.m. during 26 weeks per year. Key Messages: The model of the flying intervention team is likely to reduce time delays since processes will be performed in parallel, rather than consecutively, and since it is quicker to move a medical team rather than a patient. This project is currently under evaluation (clinicaltrials NCT04270513).
A guide to lifting aperiodic structures
Creators: name: Baake, Michael
name: Ecija, David
name: Grimm, Uwe
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Metric Geometry (math.MG)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 53C23

description: The embedding of a given point set with non-crystallographic symmetry into higher-dimensional space is reviewed, with special emphasis on the Minkowski embedding known from number theory. This is a natural choice that does not require an a priori construction of a lattice in relation to a given symmetry group. Instead, some elementary properties of the point set in physical space are used, and explicit methods are described. This approach works particularly well for the standard symmetries encountered in the practical study of quasicrystalline phases. We also demonstrate this with a recent experimental example, taken from a sample with square-triangle tiling structure and (approximate) twelvefold symmetry.
description: 8 pages, many figures
3D-SeboSkin Model for Human ex vivo Studies of Hidradenitis Suppurativa/Acne Inversa
Creators: name: Hou, Xiaoxiao
name: Hossini, Amir M.
name: Nikolakis, Georgios
name: Balthasar, Ottfried
name: Kurtz, Andreas
name: Zouboulis, Christos C.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: Hidradenitis suppurativa
subject: Skin model
subject: Ex vivo
subject: 3D-SeboSkin
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Hidradenitis suppurativa/acne inversa (HS) is a chronic, recurrent inflammatory skin disease. Its pivotal pathogenetic event is believed to be the occlusion of the hair follicle generating a perifollicular lympho-histiocytic inflammation. However, knowledge of the exact HS pathogenesis requires further research. Objective: To develop a human HS model applicable in preclinical research which could help to understand the pathophysiology of HS and to determine the action of therapeutic candidates. Methods: The 3D-SeboSkin technology was applied to maintain explants of involved and uninvolved skin of HS patients ex vivo for 3 days. Detection of differential expression of previously detected HS biomarkers was performed by immunohistochemistry in a group of female patients (n = 9, mean age 37.2 +/- 8.4 years). Results: The application of the 3D-SeboSkin model preserved the structural integrity of lesional and perilesional HS skin ex vivo, as previously described for healthy skin. Moreover, the HS 3D-SeboSkin setting maintained the differential expression and pattern of several HS biomarkers (S100A9, KRT16, SERPINB3) in epidermal and dermal tissue and the appendages. Conclusion: We have validated HS 3D-SeboSkin as a reproducible, human model, which is appropriate for preclinical lesional and perilesional HS skin studies ex vivo.
Načrti ravnanja z raziskovalnimi podatki
Creators: name: Kotar, Mojca
Publisher: name: Zenodo
Year: 2020

description: Predstavitev Načrti ravnanja z raziskovalnimi podatki z zaključne konference projekta za vzpostavitev slovenskega vozlišča Združenja za raziskovalne podatke Raziskovalni podatki in Evropski oblak odprte znanosti.
Hybrid simulation of a parallel collisionless shock in the Large Plasma Device
Creators: name: Weidl, M. S.
name: Winske, D.
name: Jenko, F.
name: Niemann, C.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: We present two-dimensional hybrid kinetic/magnetohydrodynamic simulations of planned laser-ablation experiments in the Large Plasma Device (LAPD). Our results, based on parameters which have been validated in previous experiments, show that a parallel collisionless shock can begin forming within the available space. Carbon-debris ions that stream along the magnetic-field direction with a blow-off speed of four times the Alfven velocity excite strong magnetic fluctuations, eventually transfering part of their kinetic energy to the surrounding hydrogen ions. This acceleration and compression of the background plasma creates a shock front, which satisfies the Rankine-Hugoniot conditions and can therefore propagate on its own. Furthermore, we analyze the upstream turbulence and show that it is dominated by the right-hand resonant instability.
description: 13 pages, 17 figures. Accepted at Physics of Plasmas
The development of an advanced attributed adjacency based feature extraction system for process planning in machining operations
Creators: name: McCormack, Andrew.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Clustering of microscopic particles in constricted blood flow
Creators: name: Bächer, Christian
name: Schrack, Lukas
name: Gekle, Stephan
Publisher: name: arXiv
Year: 2016
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: A mixed suspension of red blood cells (RBCs) and microparticles flows through a cylindrical channel with a constriction mimicking a stenosed blood vessel. Our three-dimensional Lattice-Boltzmann simulations show that the RBCs are depleted right ahead and after the constriction. Although the RBC mean concentration (hematocrit) is 16.5% or 23.7%, their axial concentration profile is very similar to that of isolated tracer particles flowing along the central axis. Most importantly, however, we find that the stiff microparticles exhibit the opposite behavior. Arriving on a marginated position near the channel wall, they can pass through the constriction only if they find a suitable gap to dip into the dense plug of RBCs occupying the channel center. This leads to a prolonged dwell time and, as a consequence, to a pronounced increase in microparticle concentration right in front of the constriction. For biochemically active particles such as drug delivery agents or activated platelets this clustering may lead to physiologically relevant hot spots of biochemical activity.
Supplemental Material for Dyment et al., 2020
Creators: name: Dyment, David A
name: Schock, Sarah
name: Deloughery, Kristen
name: Tran, Minh
name: Ure, Kerstin
name: Lauryl M. J. Nutter
name: Creighton, Amie
name: Yuan, Julie
name: Banderali, Umberto
name: Comas, Tanya
name: Baumann, Ewa
name: Jezierski, Anna
name: Care4Rare Canada Consortium
name: Boycott, Kym
name: Mackenzie, Alex
name: Martina, Marzia
Publisher: name: GSA Journals
Year: 2020
Subjects: subject: 110903 Central Nervous System
subject: FOS: Clinical medicine
subject: 110311 Medical Genetics (excl. Cancer Genetics)
subject: FOS: Basic medicine

description: Supplemental Material for Dyment et al., 2020
Activation cross sections of proton and deuteron induced nuclear reactions on holmium and erbium, related to the production of $^{161}$Er and $^{160}$Er medical isotopes
Creators: name: Tárkányi, F.
name: Ditrói, F.
name: Takács, S.
name: Hermanne, A.
name: Baba, M.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Experimental excitation functions for long-lived products in proton induced reactions were measured with the activation method in the 37-65 MeV energy range on natural holmium. Stacked foil irradiation technique and high resolution gamma spectrometry were used in order to measure cross-section data for the production of $^{161}$Er, $^{160}$Er and $^{159,157}$Dy. For comparison of the production routes of medically related $^{161}$Er and $^{160}$Er radioisotopes new experimental cross section data were deduced for the $^{162}$Er(p,x)$^{161,160}$Er and $^{162}$Er(d,x)$^{161,160}$Er reactions by re-evaluating gamma-ray spectra from earlier measurements. No earlier data were found in the literature for these reactions. The experimental data are compared with results of TALYS theoretical code reported in TENDL-2015.
Application of hydrogen network and pinch analysis
Creators: name: Gray, Airlie.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Ultrafast Melting of Spin Density Wave Order in BaFe$_{2}$As$_{2}$ Observed by Time- and Angle-Resolved Photoemission Spectroscopy with Extreme-Ultraviolet Higher Harmonic Generation
Creators: name: Suzuki, H.
name: Okazaki, K.
name: Yamamoto, T.
name: Someya, T.
name: Okada, M.
name: Koshiishi, K.
name: Fujisawa, M.
name: Kanai, T.
name: Ishii, N.
name: Nakajima, M.
name: Eisaki, H.
name: Ono, K.
name: Kumigashira, H.
name: Itatani, J.
name: Fujimori, A.
name: Shin, S.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Transient single-particle spectral function of BaFe$_{2}$As$_{2}$, a parent compound of iron-based superconductors, has been studied by time- and angle-resolved photoemission spectroscopy with an extreme-ultraviolet laser generated by higher harmonics from Ar gas, which enables us to investigate the dynamics in the entire Brillouin zone. We observed electronic modifications from the spin-density-wave (SDW) ordered state within $\sim$ 1 ps after the arrival of a 1.5 eV pump pulse. We observed optically excited electrons at the zone center above $E_{F}$ at 0.12 ps, and their rapid decay. After the fast decay of the optically excited electrons, a thermalized state appears and survives for a relatively long time. From the comparison with the density-functional theory band structure for the paramagnetic and SDW states, we interpret the experimental observations as the melting of the SDW. Exponential decay constants for the thermalized state to recover back to the SDW ground state are $\sim$ 0.60 ps both around the zone center and the zone corner.
Ink particle removal @ Visy Paper 4 de-inking line, through cleaner selection and dispersion optimisation
Creators: name: Karabadjak, Salih.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Real world data collection and analysis to support passenger car safety
Creators: name: Welsh, Ruth
Publisher: name: Loughborough University
Year: 2023
Subjects: Design not elsewhere classified

description: Despite advances in road safety, there are still in the region of 1,400 people killed on the road each year in GB and almost 19,000 across Europe. As part of the initiatives directed at tackling road deaths, the research community aims to provide evidence in support of informed decision making on the part of stakeholders such as policy makers and vehicle manufacturers. A rich source of information, from which evidence can be gathered, is real world data in the form of both accident data and data obtained from driving studies. Exploitation of these sources form the basis of this thesis where the author considers two primary research questions: RQ1: How can real world accident data contribute to improved passenger car safety? RQ2: How can real world driving studies contribute to improved passenger car safety? The 10 publications presented demonstrate how the author has addressed these research questions. They illustrate firstly the author’s research contribution, using real world accident data, to the evolution and impact assessment of passenger car safety testing programmes along with the development of Advanced Driver Assistance Systems (ADAS). They then discuss methodological aspects related to driving studies and how such studies can be used to assess the impact of ADAS. It is concluded that real world evidence, from what can be considered a living laboratory, provides an extremely valuable resource for monitoring passenger car safety, assessing the effectiveness of interventions to improve safety and supporting legislative development. There is still a significant role for both types of data as these will provide the ground-truth, complimenting validation and verification taking place in the simulated environment.
Bounds on Large Extra Dimensions from the Generalized Uncertainty Principle
Creators: name: Cavaglia, Marco
name: Harms, Benjamin
name: Hou, Shaoqi
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The Generalized Uncertainty Principle (GUP) implies the existence of a physical minimum length scale $l_m$. In this scenario, black holes must have a radius larger than $l_m$. They are hotter and evaporate faster than in standard Hawking thermodynamics. We study the effects of the GUP on black hole production and decay at the LHC in models with large extra dimensions. Lower bounds on the fundamental Planck scale and the minimum black hole mass at formation are determined from black hole production cross section limits by the CMS Collaboration. The existence of a minimum length generally decreases the lower bounds on the fundamental Planck scale obtained in the absence of a minimum length.
description: 17 pages, 7 figures
USIA World Survey 3
Creators: name: USIA
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: The Philippines' most important problem; the Philippines' friends and enemies; attitude toward U.S., U.S.S.R., Communist China, India, and Japan; basic interests of the Philippines, U.S., and U.S.S.R; U.S., Russian, and Chinese foreign policy; Philippines neutrality; world leaders; dispute between Malaysia and Indonesia; strongest world power in military, economic strength, education, scientific development, space development; moon landing; comparison between U.S. and U.S.S.R. regarding citizens' economic opportunity and political activity; life in Communist China; population control; U.N. voting and financial costs to members; Communist China in U.N.; Chinese imperialism; Vietnam; U.S., Russian, and China's policies regarding Vietnam; Black people in US; respondent's satisfaction with standard of living; need for economic and social reforms; reasons for poverty; U.S. companies in the Philippines; media preferences; newspaper; motion pictures; television; foreign radio broadcasts; BBC; Voice of America; Radio Peking.
Cosmological implications of Higgs field fluctuations during inflation
Creators: name: Grobov, A. V.
name: Konoplich, R. V.
name: Rubin, S. G.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Cosmological implications of Higgs field fluctuations during inflation are considered. This study is based on the Standard Model and the standard quadratic model of chaotic inflation where the Higgs field is minimally coupled to gravity and has no direct coupling to the inflaton. In the Standard model the renormalisation group improved effective potential develops an instability (an additional minimum and maximum) at large field values. It is shown that such a new maximum should take place at an energy scale above $10^{14} \;\text{GeV},$ otherwise a universe like ours is extremely unlikely. The extension to the case of the Higgs field interacting with the inflaton field is discussed.
Low-energy physics of three-orbital impurity model with Kanamori interaction
Creators: name: Horvat, Alen
name: Zitko, Rok
name: Mravlje, Jernej
Publisher: name: arXiv
Year: 2016
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We discuss the low-energy physics of the three-orbital Anderson impurity model with the Coulomb interaction term of the Kanamori form which has orbital SO(3) and spin SU(2) symmetry and describes systems with partially occupied $t_{2g}$ shells. We focus on the case with two electrons in the impurity that is relevant to Hund's metals. Using the Schrieffer-Wolff transformation we derive an effective Kondo model with couplings between the bulk and impurity electrons expressed in terms of spin, orbital, and orbital quadrupole operators. The bare spin-spin Kondo interaction is much smaller than the orbit-orbit and spin-orbital couplings or is even ferromagnetic. Furthermore, the perturbative scaling equations indicate faster renormalization of the couplings related to orbital degrees of freedom compared to spin degrees of freedom. Both mechanisms lead to a slow screening of the local spin moment. The model thus behaves similarly to the related quantum impurity problem with a larger SU(3) orbital symmetry (Dworin-Narath interaction) where this was first observed. We find that the two problems actually describe the same low-energy physics since the SU(3) symmetry is dynamically established through the renormalization of the splittings of coupling constants to zero. The perturbative renormalization group results are corroborated with the numerical-renormalization group (NRG) calculations. The dependence of spin Kondo temperatures and orbital Kondo temperatures as a function of interaction parameters, the hybridization, and the impurity occupancy is calculated and discussed.
description: 12 pages
Isn't a number and a URL enough? Why PIDs matter and technical solutions alone are not sufficient.
Creators: name: Schrader, Antonia C.
name: Hagemann-Wilholt, Stephanie
name: Czerniak, Andreas
Publisher: name: Zenodo
Year: 2023
Subjects: Persistent Identifier
Research Data Management
Metadata
Base Service
NFDI
Open Science

description: In the presentation, we introduce the two projects PID4NFDI and PID Network Germany that deal with PIDs at the national level, present some initial findings and highlight their benefit for NFDI. PIDs are used and needed along the entire lifecycle of research data: from enabling to connecting. However, a particular focus for the presentation will be laid on harmonising and connecting.
PSA001: Social Faces
Creators: name: Coles, Nicholas A.
name: Buchanan, Erin Michelle
name: Forscher, Patrick S.
name: Marton Kovacs
name: Lewis, Savannah C
name: Jones, Benedict C.
name: DeBruine, Lisa
name: Flake, Jessica Kay
name: Janssen, Steve M. J.
name: Cubillas, Carmelo P.
name: Chartier, Christopher R.
name: Levitan, Carmel
name: Dtt
name: Martinez, Jessica
name: Jernsäther, Teodor
name: Marcu, Gabriela Mariana
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: PsySciAcc
subject: Psychological Science Accelerator
subject: Psy Sci Accelerator
subject: Open Science

description: Plans, materials, data, and other project-related materials for the Global Valence Dominance Model Test (PSA001)
Precipitation hardening of magnesium-zinc-aluminium casting alloys
Creators: name: Mendis, Chamini Lakshi.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Selective crystallisation facilitated by nanonucleants for downstream bioseparation of a protein mixture
Creators: name: Li, Xiaoyu
Publisher: name: Imperial College London
Year: 2021

description: Bioseparation is a major bottleneck in the manufacture of biopharmaceuticals such as proteins. Crystallisation is a cost-effective, rapid, and robust alternative technology to conventional chromatography steps in downstream separation processes. This thesis aims to investigate protein crystallisation as a feasible approach to separate proteins from a mixture for bioseparation. In this work, lysozyme- thaumatin mixture is used as the model binary protein mixture. Both µL-scale hanging-drop vapour-diffusion (HDVD) and mL-scale batch crystallisation methods were employed. We report an experimental evidence of direct selective protein crystallisation from a binary protein mixture solution where both proteins are supersaturated and crystallisable under an identical crystallisation condition. Results from both methods showed that protein impurity, even at low concentration level, would delay target protein crystallisation with an extended induction time. When silica particles were introduced as nanonucleants to facilitate crystallisation, target protein crystallisation was significantly improved with much shorter induction time. It was also indicated that the effectiveness of silica on crystallisation depended on the type of silica particle, silica loading amount, and impurity concentration. This study also revealed the critical role of agitation in obtaining consistent and reproducible results when moving from preliminary qualitative screenings using HDVD method to quantitative batch crystallisation experiments. Apart from improving reproducibility of crystallisation experiments, agitation also had impacts on both crystallisation rate, yield, and crystal size. In conclusion, this work demonstrates that protein crystallisation is a feasible and scalable methodology to separate a target protein from a complex mixture environment.
Whose Archives? Reflections on ethics and the cultural significance of web archiving
Creators: name: Brügger. Niels
Publisher: name: Zenodo
Year: 2023

description: Jessica Ogden, Discussion session: Web archives and the ethics of deletion: Whose Archives? Reflections on ethics and the cultural significance of web archiving,
 Aarhus Autumn Meeting 2021, Friday 5 November
A Python-oriented environment for climate experiments at scale in the frame of the European Open Science Cloud
Creators: name: Elia, D.
name: Antonio, F.
name: Palazzo, C.
name: Nassisi, P.
name: Bendoukha, S.
name: Kwee-Hinzmann, R.
name: Fiore, S.
name: Weigel, T.
name: Thiemann, H.
name: Aloisio, G.
Publisher: name: Zenodo
Year: 2020

description: Presentation discussed during the "Earth/Environmental Science Applications on HPC and Cloud Infrastructures" session of the EGU 2020 General Assembly and related to the abstract available at https://doi.org/10.5194/egusphere-egu2020-17031
A Glivenko-Cantelli Theorem for almost additive functions
Creators: name: Schumacher, Christoph
name: Schwarzenberger, Fabian
name: Veselic, Ivan
Publisher: name: arXiv
Year: 2016
Subjects: subject: Probability (math.PR)
subject: Statistics Theory (math.ST)
subject: FOS: Mathematics
subject: 60F99, 60B12, 62E20, 60K35

description: We develop a Glivenko--Cantelli theory for monotone, almost additive functions of i.\,i.\,d.\ sequences of random variables indexed by~$\Z^d$. Under certain conditions on the random sequence, short range correlations are allowed as well. We have an explicit error estimate, consisting of a probabilistic and a geometric part. We apply the results to yield uniform convergence for several quantities arising naturally in statistical physics.
description: 31 pages, to appear in Stochastic Processes and Applications
Modular symmetry in magnetized/intersecting D-brane models
Creators: name: Kobayashi, Tatsuo
name: Nagamoto, Satoshi
name: Uemura, Shohei
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the modular symmetry in four-dimensional low-energy effective field theory, which is derived from type IIB magnetized D-brane models and type IIA intersecting D-brane models. We analyze modular symmetric behaviors of perturbative terms and non-perturbative terms induced by D-brane instanton effects. Anomalies are also investigated and such an analysis on anomalies suggests corrections in effective field theory.
description: 18 pages
Effects of anisotropy and Coulomb interactions on quantum transport in a quadruple quantum-dot structure
Creators: name: Kagan, M. Yu.
name: Val'kov, V. V.
name: Aksenov, S. V.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present analytical and numerical investigation of spectral and transport properties of a quadruple quantum-dot (QQD) structure which is one of the popular low-dimensional systems in the context of fundamental quantum physics study, future electronic applications and quantum calculations. The density of states, occupation numbers and conductance of the structure were analyzed using the nonequilibrium Green's functions in the tight binding approach and the equation-of-motion method. In particular the anisotropy of hopping integrals and on-site electron energies as well as the effects of the finite intra- and interdot Coulomb interactions were investigated. It was found out that the anisotropy of the kinetic processes in the system leads to the Fano-Feshbach asymmetrical peak. We demonstrated that the conductance of QQD device has a wide insulating band with steep edges separating triple-peak structures if the intradot Coulomb interactions are taken into account. The interdot Coulomb correlations between the central QDs result in the broadening of this band and the occurrence of an additional band with low conductance due to the Fano antiresonances. It was shown that in this case the conductance of the anisotropic QQD device can be dramatically changed by tuning the anisotropy of on-site electron energies.
description: 21 pages, 25 figures
The Orion HII Region and the Orion Bar in the Mid-Infrared
Creators: name: Salgado, F.
name: Berné, O.
name: Adams, J. D.
name: Herter, T. L.
name: Tielens, A. G. G. M.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present mid-infrared photometry of the Orion Bar obtained with FORCAST aboard SOFIA at 6.4, 6.6, 7.7, 19.7, 31.5 and 37.1 \um. By complementing this observations with archival FORCAST and \emph{Herschel}/PACS images we are able to construct a complete infrared spectral energy distribution of the Huygens region in the Orion nebula By comparing the infrared images with gas tracers, we find that PACS maps trace the molecular cloud, while the FORCAST data trace the photodissociation region (PDR) and HII region. Analysis of the energetics of the region reveal that the PDR extends for 0.28~pc along the line-of-sight and that the Bar is inclined at an angle of $4\degr$. The infrared and submillimeter images reveal that the Orion Bar represents a swept up shell with a thickness of 0.1~pc. The mass of the shell implies a shock velocity of $\simeq 3$ km/s and an age of $\simeq 10^5$ yr for the HII region. Our analysis shows that the UV and infrared dust opacities in the HII region and the PDR are a factor 5 to 10 lower than in the diffuse interstellar medium. In the ionized gas, Ly$α$ photons are a major source of dust heating at distances larger than $\simeq0.06$~pc from \toc. Dust temperatures can be explained if the size of the grains is between 0.1 to 1~\um. We derive the photo-electric heating efficiency of the atomic gas in the Orion Bar. The results are in good qualitative agreement with models and The quantitative differences indicate a decreased PAH abundance in this region.
Deep audio-visual speech recognition
Creators: name: Ma, Pingchuan
Publisher: name: Imperial College London
Year: 2022

description: Decades of research in acoustic speech recognition have led to systems that we use in our everyday life. However, even the most advanced speech recognition systems fail in the presence of noise. The degraded performance can be compensated by introducing visual speech information. However, Visual Speech Recognition (VSR) in naturalistic conditions is very challenging, in part due to the lack of architectures and annotations. This thesis contributes towards the problem of Audio-Visual Speech Recognition (AVSR) from different aspects. Firstly, we develop AVSR models for isolated words. In contrast to previous state-of-the-art methods that consists of a two-step approach, feature extraction and recognition, we present an End-to-End (E2E) approach inside a deep neural network, and this has led to a significant improvement in audio-only, visual-only and audio-visual experiments. We further replace Bi-directional Gated Recurrent Unit (BGRU) with Temporal Convolutional Networks (TCN) to greatly simplify the training procedure. Secondly, we extend our AVSR model for continuous speech by presenting a hybrid Connectionist Temporal Classification (CTC)/Attention model, that can be trained in an end-to-end manner. We then propose the addition of prediction-based auxiliary tasks to a VSR model and highlight the importance of hyper-parameter optimisation and appropriate data augmentations. Next, we present a self-supervised framework, Learning visual speech Representations from Audio via self-supervision (LiRA). Specifically, we train a ResNet+Conformer model to predict acoustic features from unlabelled visual speech, and find that this pre-trained model can be leveraged towards word-level and sentence-level lip-reading. We also investigate the Lombard effect influence in an end-to-end AVSR system, which is the first work using end-to-end deep architectures and presents results on unseen speakers. We show that even if a relatively small amount of Lombard speech is added to the training set then the performance in a real scenario, where noisy Lombard speech is present, can be significantly improved. Lastly, we propose a detection method against adversarial examples in an AVSR system, where the strong correlation between audio and visual streams is leveraged. The synchronisation confidence score is leveraged as a proxy for audio-visual correlation and based on it, we can detect adversarial attacks. We apply recent adversarial attacks on two AVSR models and the experimental results demonstrate that the proposed approach is an effective way for detecting such attacks.
title: Culturology
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2023

description: The educational manual for the course “Culturology” considers culture as a phenomenon of a human\'s spiritual life and its material manifestations. The book contains a thematic plan, texts, questions and tasks, literature sources for each section. Theoretical questions of culture and historical aspects of the cultural heritage of Russia are considered. The educational manual is created for students of medical universities and has been prepared in accordance with the requirements of the current Federal State Educational Standard for Higher Education of a specialist in the specialty “General Medicine” and the academic course working program of the discipline “Culturology”, approved by Coordinating Council for the field of education “Health and medical sciences”.
Investigation of zero-net-mass flux jets in crossflow
Creators: name: Gordon, Mark.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Nodal Brillouin Zone Boundary from Folding a Chern Insulator
Creators: name: Lang, Li-Jun
name: Zhang, Shao-Liang
name: Zhou, Qi
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Chern insulator is a building block of many topological quantum matters, ranging from quantum spin Hall insulators to fractional Chern insulators. Here, we discuss a new type of insulator, which consists of two half filled ordinary Chern insulators. On the one hand, the bulk energy spectrum is obtained from folding that of either Chern insulator. Such folding gives rise to a nodal boundary of the Brillouin zone, at which the band crossing is protected by the symmetries of the two-dimensional lattice that is invariant under combined transformations in the spatial and the spin space. It also provides one a natural platform to explore the non-abelian Berry curvature and the resultant quantum phenomena. On the other hand, these two underlying Chern insulators are distinguished from each other by nonsymmorphic operators, which lead to intriguing properties absent in conventional Chern insulators. A new degree of freedom, the parity of the nonsymmorphic symmetry, needs to be introduced for describing the topological pumping, if the edge respects the nonsymmorphic symmetry.
description: 12 pages, 10 figures
The Discovery of Solar-like Activity Cycles Beyond the End of the Main Sequence?
Creators: name: Route, Matthew
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The long-term magnetic behavior of objects near the cooler end of the stellar main sequence is poorly understood. Most theoretical work on the generation of magnetism in these ultracool dwarfs (spectral type >=M7 stars and brown dwarfs) suggests that their magnetic fields should not change in strength and direction. Using polarized radio emission measurements of their magnetic field orientations, I demonstrate that these cool, low-mass, fully-convective objects appear to undergo magnetic polarity reversals analogous to those that occur on the Sun. This powerful new technique potentially indicates that the patterns of magnetic activity displayed by the Sun continue to exist, despite the fully convective interiors of these objects, in contravention of several leading theories of the generation of magnetic fields by internal dynamos.
description: Accepted to ApJL; 6 pages, 1 table
title: The Effects of Exercise on Women's Self-Esteem
Creators: name: Biddle, Wendy Laurie
Publisher: name: Old Dominion University Libraries
Year: 1982

description: The effects of a 12-week session of aerobic dancing were examined on two groups of women, assigned into fit and unfit groups. The subjects had voluntarily enrolled in aerobic dancing prior to the study. Self-Esteem scores were obtained using the Rosenberg Self-Esteem Scale during the first and tenth or eleventh weeks of the session. Pretest and posttest scores were analyzed along with the variables of age, marital status, weight loss, and smoking habits. A significantly higher gain score (posttest score subtracted from pretest score) was found on those women who attended three weekly classes compared to those who attended two weekly classes. A significant difference on gain scores was also found between those who had lost weight and those who had not (women who lost weight gained more in self-esteem). Significant differences were also found on pretest scores between fit married and single women, and between smokers and nonsmokers (fit married women and nonsmokers had higher self-esteems).
FAIR in reproduktibilni podatki na ustanovi s podporo orodja pISA-tree
Creators: name: Blejec, Andrej
Publisher: name: Zenodo
Year: 2020

description: Sodobne zahteve deljenja javno dostopnih podatkov in upoštevanje FAIR principa predstavlja relativno novost za raziskovalce. Raziskovalci se pogosto o potrebi in načinu deljenja podatkov srečajo šele na koncu raziskave. Veliko učinkoviteje pa je o tem razmišljati pred in med samim potekom raziskave. V prispevki je predstavljen način upravljanja s podatki in organizacije podatkov na nivoju raziskovalne skupine ali manjše institucije že med potekom raziskave. Predstavljeno bo na našem oddelku razvito orodje pISA-tree, ki omogoča konsistentno organizacijo podatkov že med raziskavo. Podatki so organizirani v skladu s pricipoma ISA in FAIR, ter opremljeni z metapodatki, ki jih potrebujemo za avtomatizirano deponiranje na platforme z odprtim dostopom do podatkov (npr. FAIRDOMhub).
Bifurcations in Delay Differential Equations: an algorithmic approach in frequency domain
Creators: name: Bel, Andrea
name: Reartes, Walter
name: Torresi, Ana
Publisher: name: arXiv
Year: 2016
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: In this work we study local oscillations in delay differential equations with a frequency domain methodology. The main result is a bifurcation equation from which the existence and expressions of local periodic solutions can be determined. We present an iterative method to obtain the bifurcation equation up to a fixed arbitrary order. It is shown how this method can be implemented in symbolic math programs.
description: 20 pages
The feedback of atomic jets from embedded protostars in NGC 1333
Creators: name: Dionatos, Odysseas
name: Güdel, Manuel
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Star-formation feedback onto the parent cloud is conventionally examined through the study of molecular outflows. Little is however known on the effect that atomic ejecta, tracing fast shocks, can have on the global cloud properties. In this study we employ Herschel/PACS [OI] and [CII] spectral line maps of the NGC 1333 star-forming region to assess the relative influence of atomic jets onto the star-formation process. Atomic line maps are compared against molecular outflow tracers and atomic ejecta are associated to individual driving sources. We study the detailed morphology and velocity distribution of [OI] line using channel and line-centroid maps and derive the momentum, energy, and mass flux for all the bipolar jets traced by [OI] line emission. We find that the line-centroid maps can trace velocity structures down to 5 km s$^{-1}$ which is a factor of $\sim$20 beyond the nominal velocity resolution reached by Herschel/PACS. These maps reveal an unprecedented degree of details that assist significantly in the association and characterization of jets and outflows. Comparisons of the dynamical and kinematical properties shows that [OI] momentum accounts for only $\sim$1% of the momentum carried by the large scale CO outflows but the energy released through the jets corresponds to 50 - 100% of the energy released in outflows. The estimated ratios of the jet to the outflow momenta and energies are consistent with the results of two-component, nested jet/outflow simulations, where jets are associated to episodic accretion events. Under this scenario, the energy from atomic jets to the cloud is as important as the energy output from outflows in maintaining turbulence and dissipating the cloud gas.
description: 14 pages, 8 figures, 3 tables. Accepted for publication in A&A
title: Philosophy: sociocultural and anthropological aspects
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2023

description: The educational manual “Philosophy: sociocultural and anthropological aspects” philosophy is considered from the standpoint of a centuries-old tradition of the possibilities and limits of human analysis of the world in the context of various options for constructing socio-cultural systems. The manual contains main lines, questions and tasks, references for each section. The educational manual is created for students of medical universities and has been prepared in accordance with the requirements of the current Federal State Educational Standard for Higher Education of a specialist in the specialty “General Medicine” and the academic course working program of the discipline “Philosophy”, approved by Coordinating Council for the field of education “Health and medical sciences”.