cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Does gender influence discussion forum participation in online education?
Creators: name: Mazzolini, Margaret
name: Maddison, Sarah
Publisher: name: Swinburne
Year: 2024

description: In this study we have investigated aspects of women students’ participation in asynchronous discussion forums in an online education context where the women were heavily outnumbered by men. We found that the perceptions of the women concerning how often they participated and the grade they expected, as compared to the men, did not necessarily agree with a statistical analysis of what actually happened. We studied qualitative feedback by the women participants on their experiences in the forums in order to try to understand the reasons for this gap between perceptions and reality. As a result of this project, we foreshadow further studies that might help us form strategies to encourage confident participation by women in online education forums.
title: Nucleus-nucleus potentials from local chiral EFT interactions
Creators: name: Durant, V.
name: Capel, P.
name: Schwenk, A.
Publisher: name: IOP Publishing
Year: 2024

description: We present the first determination of double-folding potentials (DFP) based on chiral effective field theory (EFT) nucleon-nucleon interactions at next-to-next-to-leading order (N²LO). To this end, we construct new two-body soft local chiral EFT interactions. We benchmark this approach in ¹⁶O-¹⁶O collisions, and extend it to the scattering of ¹²C-¹²C. We present results for cross sections computed for elastic scattering at energies up to 1000 MeV, as well as for the astrophysical S factor of the fusion of oxygen isotopes. Thanks to the predictive power of this approach, we can calculate various reaction observables without any adjusting parameters. Our analysis of these various reaction observables has enabled us to study the impact of the nuclear density and the nucleon-nucleon interaction on the corresponding cross sections.
Uniformity and Differentiation in the Fundamentals of EU Membership: The EU Rule of Law Acquis in the Pre- and Post-accession Contexts
Creators: name: Damjanovski, Ivan
name: Hillion, Christophe
name: Preshova, Denis
Publisher: name: Zenodo
Year: 2020
Subjects: European Union
Differentiated integration
EU Rule of Law
EU Enlargement

description: The paper discusses the nexus between the EU pre-accession conditionality and membership obligations to guarantee respect for the rule of law as a founding value of the EU, common to the Member States. It does so through the prism of the notions of legal uniformity and differentiation. The paper examines how the EU’s rule of law promotion in the accession process converges with and potentially inspires the progressive EU articulation of standards applicable to the Member States. By focusing on the judicial dimension of the rule of law, it is argued that while a certain diversity is conceivable in the manner in which the rule of law is observed, and more specifically in how judicial independence is achieved at the national level, there is a functional rationale for the EU to circumscribe the heterogeneity of national judicial systems – and accordingly, for elaborating common rule of law standards in the EU.
An off-on fluorescent sensor with high selectivity and sensitivity for Fe(III)
Creators: name: Junmei An
name: Tianrong Li
name: Baodui Wang
name: Zhengyin Yang
name: Mihui Yan
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: A new fluorescent derivative (1) containing coumarin exhibits Fe(III)-selective strong yellow-green fluorescence in ethanol. This compound could be used as an “off-on” chemosensor and allow the detection of Fe3+ by monitoring changes in absorption and fluorescence spectra. Upon addition of Fe3+, an overall emission change of 125-fold was observed. High selectivity and sensitivity was observed over other metal ions, mainly due to the spirolactam ring-opening power of Fe3+. The detection limit was as low as 5.6 ppb. Photo-induced electron transfer (PET), coupled with intramolecular charge transfer (ICT) are proposed to account for the observed spectral response.
title: Jacques Leibowitch "Draft protocole concernant un médicament ou un dispositif médical : HIV light"
Creators: name: Leibowitch, Jacques
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: http://www.calames.abes.fr/pub/ms/Calames-2019311113283126
description: created: start=1975;end=2018
Splat microstructure of plasma sprayed cast iron with different chamber pressures
Creators: name: Morks, M. F.
name: Tsunekawa, Y.
name: Okumiya, M.
name: Shoeib, M. A.
Publisher: name: Swinburne
Year: 2024

description: Achieving a plasma sprayed cast iron coating containing graphite requires stringent control on spray parameters that synergistically influence the coating properties and thus the performance. The microstructure of cast iron splats greatly depends on spray parameters such as substrate temperature, chamber pressure, and spray distance. This paper presents the effect of chamber pressure on the splat microstructure, including oxides and graphite. At low chamber pressures, most splats exhibit a disk shape with high flattening ratios, whereas star-shaped splats extensively appear at high chamber pressures. Spraying at high chamber pressures causes the formation of pores and thick oxide zones at the splat/substrate interface, mainly due to the atmospheric gases, which are responsible for a decrease in splat adhesion. Spraying in Ar atmosphere reduces the splat oxidation due to a decrease in the oxygen partial pressure. Small deformed substrate ridges are observed adjacent to the periphery of splats sprayed at low chamber pressures whereas no ridges are detected at high chamber pressures. Ridge formation generates a kind of mechanical bond, which increases the adhesive strength. Since the molten droplets impinge with high velocity and thus high flattening ratio at low chamber pressures, the solidification rate becomes faster, and graphite formation is resultantly hindered.
title: Préface_Poèmes par un riche amateur
Creators: name: AmateurS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021

description: Préface
description: ID_PARA_00950
An off-on fluorescent sensor with high selectivity and sensitivity for Fe(III)
Creators: name: Junmei An
name: Tianrong Li
name: Baodui Wang
name: Zhengyin Yang
name: Mihui Yan
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: A new fluorescent derivative (1) containing coumarin exhibits Fe(III)-selective strong yellow-green fluorescence in ethanol. This compound could be used as an “off-on” chemosensor and allow the detection of Fe3+ by monitoring changes in absorption and fluorescence spectra. Upon addition of Fe3+, an overall emission change of 125-fold was observed. High selectivity and sensitivity were observed over other metal ions, mainly due to the spirolactam ring-opening power of Fe3+. The detection limit was as low as 5.6 ppb. Photo-induced electron transfer, coupled with intramolecular charge transfer are proposed to account for the observed spectral response.
Improving the usability of novel web software: an industrial case study of an institutional repository
Creators: name: McKay, Dana
name: Burriss, Shaun
Publisher: name: Swinburne
Year: 2024

description: In this paper we discuss usability improvements made to institutional repository software in an industrial setting. The novelty of institutional repository software as a class and the industrial setting present special challenges to traditional usability evaluation; here examine these problems and present a case study which demonstrates a combination of heuristic analysis, empirical methods, background research and interface best practice to make significant usability improvements to an institutional repository.
title: Corona Constitutional #39: Stare Decisis
Creators: name: Steinbeis, Maximilian
Publisher: name: Fachinformationsdienst für internationale und interdisziplinäre Rechtsforschung
Year: 2020
Subjects: subject: 342

description: Gestern hat der US Supreme Court ein Gesetz gekippt, das eine Abtreibung im Bundesstaat Louisiana nahezu unmöglich gemacht hätte. Die entscheidende Stimme kam von Chief Justice Roberts, einem erzkonservativen Abtreibungsgegner. Während sich Liberale erfreut die Augen reiben und das Weiße Haus ein “unglückliches Urteil” beklagt, wird STEPHEN F. ROSS von der Penn State Law School misstrauisch: Könnte es sein, dass Trumps scheinbarer Rückschlag eigentlich ein Wahlkampfgeschenk ist — in Abtreibungsdebatte verpackt und mit verfassungsrechtlichem Schleifchen verziert? Diese These bespricht er im heutigen Podcast-Interview mit Max Steinbeis.
description: Verfassungsblog: On Matters Constitutional
EVALUACIÓN DEL IMPACTO EN LA UTILIZACIÓN DEL LIBRO DE CURSO EN EL RENDIMIENTO ACADÉMICO ESTUDIANTIL DE LA MATERIA DE CÁLCULO INTEGRAL, CARRERA DE INGENIERÍA AGRONÓMICA. UNIVERSIDAD CENTRAL DEL ECUADOR
Creators: name: Nicole Albarracin Alvear, Anggy
Publisher: name: unknown
Year: 2024

description: Este estudio revela que el uso regular de un manual de cálculo mejora el rendimiento académico en estudiantes de Ingeniería Agronómica, sugiriendo que materiales educativos de calidad favorecen el aprendizaje.
title: Corona Constitutional #40: Die innere Sicherheit
Creators: name: Steinbeis, Maximilian
Publisher: name: Fachinformationsdienst für internationale und interdisziplinäre Rechtsforschung
Year: 2020
Subjects: subject: 342

description: Was sich das Bundesinnenministerium eigentlich denkt, haben sich in letzter Zeit viele gefragt. Wenig präsent ist hingegen die Frage, wie das Innenministerium denkt. Der Anthropologe WERNER SCHIFFAUER erforscht die Kultur und innere Funktionsweise des BMI. Über zwiespältige Selbstbilder, institutionelle Persönlichkeitsspaltungen und autoritäres Erbgut spricht er im heutigen Podcast-Interview mit Max Steinbeis.
description: Verfassungsblog: On Matters Constitutional
title: Analysis, selection and application of costing approach providing a transparent breakdown of the variety-induced complexity in the automobile inbound logistics cost calculation for the purpose of anticipative logistics planning at the OEM
Creators: name: Jambor, Jozef
Publisher: name: TU Wien
Year: 2022
Subjects: subject: Complexity cost
subject: inbound logistics
subject: automotive industry
subject: costing approach
subject: variety-induced complexity

description: Product innovations, globalization, accelerated product life cycles, electrification, sustainability, autonomous driving, connectivity, delivery shortages in the supply chain, increased competition due to market saturation and increasing customer requirements are just a few examples of the wide range of challenges the automotive industry is facing nowadays. Especially the customer demands for individuality and his behavior with respect to lifestyle, travel, and luxury underwent a tremendous change and therefore vary broadly, which in turn affects the automotive environment widely. In order to generate individual, unique, and consumer-specific products the Original equipment manufacturers (OEM) have enlarged their offer on models and configurable options considerably. As a result, the product variety has increased to an almost infinite number of options and thus becoming unmanageable. The exploding number of product variants affects the logistics, being a vital element in the automotive sector, significantly. In particular, the inbound logistics systems respond to this impact by increasing costs and declining performance. It appears that currently used logistical cost calculation at one of the Premium OEM ́s is not sufficient to meet the demands of the modern complexity and variant management, which is in turn an important tool for managing of the product variants. Hence, the analysis, evaluation and selection of the proper cost calculation method allowing to allocate variety-induced logistics costs – the latter often considered as hidden costs of doing business – to the individual product variants is performed within the framework of this research. This thesis aims to find suitable cost calculation method to fill the gap in the missing link between the product variety-induced complexity and logistics costs accrued in the automotive inbound logistics at OEM-level. This model-based approach shall serve as an active complexity a variant management tool for the purpose of supporting product variety decisions at an early stage in the product design phase. The practicability of this method is demonstrated in the case study performed for the rear bumper system.
Finale für Titelträger*innen: Kumulative Dissertationen Open Access veröffentlichen
Creators: name: Friedrich, Marléne
Publisher: name: Zenodo
Year: 2022
Subjects: Open-Access-Publizieren
kumulative Dissertation
Zweitveröffentlichung

description: Beim Veröffentlichen eines wissenschaftlichen Beitrags räumen Autor*innen den Verlagen oft noch ausschließliche Nutzungsrechte ein. Viele Verlage gestatten eine Open-Access-Zweitveröffentlichung und die Nachnutzung von Inhalten durch die Autor*innen selbst, auch im Rahmen einer kumulativen Dissertation. Die Bedingungen unterscheiden sich jedoch zum Teil stark, zum Beispiel hinsichtlich der Vorgaben, welche Manuskriptversion genutzt werden darf. Im Open Access Talk geben wir Ihnen einen Überblick, was bei der Open-Access-Veröffentlichung von kumulativen Dissertationen zu beachten ist. Dabei gehen wir u. a. auf folgende Fragen ein: Welche Manuskriptversion(en) darf ich in meiner kumulativen Dissertation verwenden? Wie binde ich meine publizierten bzw. eingereichten und noch unveröffentlichten Artikel in die Dissertation ein? Wo finde ich Informationen zu den einzelnen Verlagspolicies? Der Vortrag wurde am 28.04.2022 im Rahmen der Webinar-Reihe Open Access Talk gehalten.
The "sustainable bee forest" concept and implementation
Creators: name: Böhling, Kathrin
Publisher: name: Zenodo
Year: 2025
Subjects: Climate adaptation
forest management
smallholder farmers
afforestation
non-wood forest products

description: The project "sustainable bee forest" develops and implements a new forest management concept that improves the habitat of flower-pollinating insects during re- and afforestation from the very beginning while generating new sources of income from non-wood forest products. This concept is a response to the need for adaptation strategies in forest management in the face of climate change. The main target group are smallholder farmers who are faced with forest dieback in the face of climate change. Large tracts of forest underwent major disturbances over the last years (pests, storms, fire). The German ministry of agriculture and food (BMEL) estimates that over the next years almost 500.000 ha of forest land will need to be afforested (status: Oct 2023).
In vitro antiplasmodial activity, cytotoxicity and chemical profiles of sponge species of Cuban coasts
Creators: name: Mendiola, Judith
name: Regalado, Erik L.
name: Díaz-García, Alexis
name: Thomas, Olivier P.
name: Aymé Fernández-Calienes
name: Hermis Rodríguez
name: Laguna, Abilio
name: Valdés, Olga
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: Aqueous and organic fractions from the crude extracts of 17 sponge species collected at Boca de Calderas, Havana, Cuba were analysed. The organic fractions of Mycale laxissima, Clathria echinata and Agelas cerebrum exhibited values of concentrations causing 50% inhibition of in vitro growth of Plasmodium berghei (IC50) of 42.3 ± 5.1, 52 ± 9.7 and 60.3 ± 10.6 μg/mL, respectively, while their selectivity indexes for fibroblast cell lines were 9.45, 4.24 and 8.7, correspondingly. These fractions reduced parasitemia of infected Balb/c mice as well. Selective cytotoxicity indexes against tumour HeLa cells focused an interest on the aqueous fraction of M. laxissima (>7.12) and organic fractions of Polymastia nigra (5.95), A. cerebrum (5.48) and Niphates erecta (>4.2). Triterpenoids/steroids and alkaloids detected in the organic fractions of M. laxissima, C. echinata and A. cerebrum should be isolated for future investigation.
title: 01_0805
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
In vitro antiplasmodial activity, cytotoxicity and chemical profiles of sponge species of Cuban coasts
Creators: name: Mendiola, Judith
name: Regalado, Erik L.
name: Díaz-García, Alexis
name: Thomas, Olivier P.
name: Aymé Fernández-Calienes
name: Hermis Rodríguez
name: Laguna, Abilio
name: Valdés, Olga
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: Aqueous and organic fractions from the crude extracts of 17 sponge species collected at Boca de Calderas, Havana, Cuba were analysed. The organic fractions of Mycale laxissima, Clathria echinata and Agelas cerebrum exhibited values of concentrations causing 50% inhibition of in vitro growth of Plasmodium berghei (IC50) of 42.3 ± 5.1, 52 ± 9.7 and 60.3 ± 10.6 μg/mL, respectively, while their selectivity indexes for fibroblast cell lines were 9.45, 4.24 and 8.7, correspondingly. These fractions reduced parasitemia of infected Balb/c mice as well. Selective cytotoxicity indexes against tumour HeLa cells focused an interest on the aqueous fraction of M. laxissima (>7.12) and organic fractions of Polymastia nigra (5.95), A. cerebrum (5.48) and Niphates erecta (>4.2). Triterpenoids/steroids and alkaloids detected in the organic fractions of M. laxissima, C. echinata and A. cerebrum should be isolated for future investigation.
Brazilian brown propolis elicits antileishmanial effect against promastigote and amastigote forms of Leishmania amazonensis
Creators: name: Santana, Lorena C.L.R.
name: Carneiro, Sabrina Maria P.
name: Caland-Neto, Laurentino B.
name: Arcanjo, Daniel D.R.
name: Moita-Neto, José M.
name: Antônia M.G.L. Citó
name: Carvalho, Fernando Aécio A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: Propolis is a complex matrix of chemical constituents extracted from plants and produced by bees which is used in folk medicine due to its several pharmacological properties. Its chemical composition varies according to the region where it is produced. This work has studied the antileishmanial activity and cytotoxicity of brown propolis (BP) originating from the semi-arid region of Piauí, Brazil. The BP showed significant inhibition of the Leishmania amazonensis promastigotes growth as well as being effective in reducing infection of murine macrophages and the number of internalised amastigotes in these cells. The dichloromethane fraction was the most active and showed the best selectivity index. The studied samples presented good activity and the fractioning improved the antileishmanial activity without an increase in the cytotoxicity against mammalian cells. Therefore, BP is a potential source for development of apitherapeutic products for the treatment of leishmaniasis.
title: Corona Constitutional #41: Apropos Hotspot
Creators: name: Steinbeis, Maximilian
Publisher: name: Fachinformationsdienst für internationale und interdisziplinäre Rechtsforschung
Year: 2020
Subjects: subject: 342

description: Während sich die mediale Aufmerksamkeit zurzeit hauptsächlich auf die neuesten Entwicklungen in der Corona-Pandemie und der Black-Lives-Matter-Bewegung richtet, droht die Situation an den EU-Außengrenzen derweil in Vergessenheit zu geraten. NIKI GEORGIOU und ROBERT NESTLER, die für die NGO „Equal Rights Beyond Borders” tätig sind, sprechen im heutigen Podcast-Interview mit Max Steinbeis über die unverändert angespannte Situation für Geflüchtete.
description: Verfassungsblog: On Matters Constitutional
Aphis spiraecola Patch 1914
Creators: name: Simbaqueba, Ronald
name: Serna, Francisco
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Aphididae
Aphis
Aphis spiraecola

description: Aphis spiraecola Patch, 1914 (Fig. 1)
Longitud 1,2 a 2,7 mm; color verde amarillento a verde manzana; sifúnculos, cauda, ápice de fémures y de tibias oscuros (Fig. 1a). Tubérculos antenales no desarrollados (Fig. 1b). Antenas de seis antenómeros de 0,5 a 0,7 veces el cuerpo. Filamento terminal 1,8 a 3 veces el tramo proximal. Alados con cuatro a doce rinarios secundarios en el antenómero III y cero a cinco en el antenómero IV. Protórax con tubérculos laterales similares que en los segmentos abdominales I y VII, rara vez con tubérculos más pequeños en los segmentos abdominales II a IV. Cutícula con reticulación poco marcada. Rostro alcanzando o sobrepasando las coxas medias (Fig. 1a). Segmentos abdominales II a IV generalmente sin papilas laterales, algunas veces hasta tres de pequeño tamaño. Sifúnculos cónicos, longitud 0,8 a 1,8 veces la cauda, con cutícula imbricada casi en su totalidad (Fig. 1e); escleritos postsifunculares presentes algunas veces. Placa genital con dos a siete setas. Cauda digitiforme con o sin constricción media, con doce a catorce setas, rara vez con seis a 16 (Fig. 1d) (Holman 1974, Bustillo y Sánchez 1977, García Prieto y Nieto Nafría. 2005, Blackman y Eastop 2006).
description: Published as part of Simbaqueba, Ronald & Serna, Francisco, 2021, Áfidos (Hemiptera: Aphididae) de Colombia, con nuevos registros para el norte de Sudamérica, pp. 1-27 in Caldasia 43 (1) on page 13, DOI: 10.15446/caldasia.v41n3.77979, http://zenodo.org/record/15265235
Marisa Bruni-Tedeschi
Creators: name: Leibowitch, Jacques (1942-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021

description: 2 fichiers
description: date: start=2011-05-26;end=2011-11-07
New cytotoxic spirostane saponin and biflavonoid glycoside from the leaves of Acacia saligna (Labill.) H.L. Wendl.
Creators: name: Gedara, Sahar R.
name: Galala, Amal A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: New naturally occurring spirostane saponin (25S)-5β-spirostan-3β-yl-3-O-β-d-xylopyranosyl(1 → 3)-O-β-d-xylopyranosyl(1 → 4)-β-d-galactopyranoside (6) and biflavonoid glycoside myricetin-3-O-rhamnoside (C7-O-C7) myricetin-3-O-rhamnoside (4) along with a series of known compounds erythrodiol (1), 3β-O-trans-p-coumaroyl-erythrodiol (2), quercetin-3-O-α-l-rhamnoside (3) and myricetin-3-O-α-l-rhamnoside (5) were separated from the leaves of Acacia saligna (Labill.), H.L. Wendl. Compounds 1 and 2 were separated for the first time from genus Acacia. The structures of compounds 1–6 were established on the basis of extensive 1D and 2D NMR spectroscopic techniques in combination with EI-MS and HR-ESI-MS. These compounds were screened for their antioxidant and cytotoxic activities against HEPG2 (liver cancer) cell line and significant results were obtained.
Further in vitro evaluation of cytotoxicity of the marine natural product derivative 4′-leucine-avarone
Creators: name: Pejin, Boris
name: Iodice, Carmine
name: Tommonaro, Giuseppina
name: Bogdanovic, Gordana
name: Kojic, Vesna
name: Rosa, Salvatore De
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: The cytotoxicity of 4′-leucine-avarone, amino derivative of the sponge Dysidea avara secondary metabolite avarone, was evaluated by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay in vitro against seven human solid tumours for the first time. The compound tested induced dose-dependent cytotoxic response in all cancer cells showing better activity towards the lung A-549 and colon HT-29 cell lines (IC50 7.40 μM and 9.62 μM, respectively) than towards the breast adenocarcinoma ER positive MCF-7 and ER negative MDA-MB-231 cells (IC50 11.64 μM and 17.31 μM, respectively), the prostate adenocarcinoma PC-3 and epiteloid cervix carcinoma HeLa cells (IC50 14.24 μM and 15.54 μM, respectively). No toxicity was found towards the foetal lung fibroblast MRC-5 cell line at the concentrations used. According to experimental data obtained, the sesquiterpenoid quinone structure of avarone may inspire development of new drug-like substances with improved cytotoxicity on lung cancer in humans.
The native production of the sesquiterpene isopterocarpolone by Streptomyces sp. RM-14-6
Creators: name: Shaaban, Khaled A.
name: Shanteri Singh
name: Elshahawi, Sherif I.
name: Xiachang Wang
name: Ponomareva, Larissa V.
name: Sunkara, Manjula
name: Copley, Gregory C.
name: Hower, James C.
name: Morris, Andrew J.
name: Madan K. Kharel
name: Thorson, Jon S.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: We report the production, isolation and structure elucidation of the sesquiterpene isopterocarpolone from an Appalachian isolate Streptomyces species RM-14-6. While isopterocarpolone was previously put forth as a putative plant metabolite, this study highlights the first native bacterial production of isopterocarpolone and the first full characterisation of isopterocarpolone using 1D and 2D NMR spectroscopy and HR-ESI mass spectrometry. Considering the biosynthesis of closely related metabolites (geosmin or 5-epiaristolochene), the structure of isopterocarpolone also suggests the potential participation of one or more unique enzymatic transformations. In this context, this work also sets the stage for the elucidation of potentially novel bacterial biosynthetic machinery.
SPIRIT. Scalable privacy preserving intelligence analysis for resolving identities. Deliverable 9.1. Informed Consent (WP9)
Creators: name: Teodoro, Emma
name: Casanovas, Pompeu
name: González-Conejero, Jorge
name: Morris, Nicholas
name: Pagallo, Ugo
name: Dignum, Virginia
name: Lilllian Mitrou
name: Watts, David
name: Sartor, Giovanni
Publisher: name: Zenodo
Year: 2020
Subjects: Informed Consent Form, Ethics, Security, Privacy, Data Protection, Personal Data, Qualitative Research

description: SPIRIT Project. Scalable Privacy Intelligence Analysis for Preserving Identities. Deliverable 9.1 provides the Informed Consent Templates Forms to be used during the requirements and use-cases elicitation activities and the evaluation phase of the SPIRIT project. Section 2 provides some insights regarding informed consent within the processing of personal data in the SPIRIT research activities. Section 3 includes a working template of the consent form that will be completed by participants involved in Task 2.1, T. 2.5 of Work Package 2. Section 4 provides an informed consent template form for the evaluation activities of the SPIRIT Platform planned in Task 8.5 of Work Package 8.
Brazilian brown propolis elicits antileishmanial effect against promastigote and amastigote forms of Leishmania amazonensis
Creators: name: Santana, Lorena C.L.R.
name: Carneiro, Sabrina Maria P.
name: Caland-Neto, Laurentino B.
name: Arcanjo, Daniel D.R.
name: Moita-Neto, José M.
name: Antônia M.G.L. Citó
name: Carvalho, Fernando Aécio A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: Propolis is a complex matrix of chemical constituents extracted from plants and produced by bees which is used in folk medicine due to its several pharmacological properties. Its chemical composition varies according to the region where it is produced. This work has studied the antileishmanial activity and cytotoxicity of brown propolis (BP) originating from the semi-arid region of Piauí, Brazil. The BP showed significant inhibition of the Leishmania amazonensis promastigotes growth as well as being effective in reducing infection of murine macrophages and the number of internalised amastigotes in these cells. The dichloromethane fraction was the most active and showed the best selectivity index. The studied samples presented good activity and the fractioning improved the antileishmanial activity without an increase in the cytotoxicity against mammalian cells. Therefore, BP is a potential source for development of apitherapeutic products for the treatment of leishmaniasis.
title: Europas Weg: Verfassungsgeschichte der Europäischen Union
Creators: name: Schorkopf, Frank
Publisher: name: Fachinformationsdienst für internationale und interdisziplinäre Rechtsforschung
Year: 2020
Subjects: subject: 340

description: Der Podcast hat das europäische Recht in seinen ideelen, politisch-gesellschaftlichen und wirtschaftlichen Zusammenhängen zum Gegenstand. Es geht um Verträge, Ereignisse und Personen, um das Denken und Sprechen, um Partizipaton und Repräsenation im organisierten Europa von der Gründung der Montanunion in den frühen 1950er Jahren bis zur Europäischen Union der 2000er Jahre. Dieses digitale Vorhaben soll die Grundlagen europäischer Integration, besonders des Europarechts für Studenten nicht nur, aber auch der Rechtswissenschaft, im Grunde jedoch allen Interessierten zugänglich machen.
Chemical, biological, morphoanatomical and antimicrobial study of Ocotea puchury-major Mart.
Creators: name: Leporatti, Maria Lucia
name: Pintore, Giorgio
name: Foddai, Marzia
name: Chessa, Mario
name: Piana, Andrea
name: Petretto, Giacomo Luigi
name: Masia, Maria Dolores
name: Mangano, Giuseppe
name: Nicoletti, Marcello
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: Ocotea puchury-major Mart. is a tree native to the Brazilian rain forest, where it is popularly known as puxurì. In local folk medicine the leaves are used for their sedative, gastroenteric and antireumatic properties. The morphoanatomical study determined those features useful in distinguishing this species from other closely related taxa. Chemical analysis was focused on the study of the volatile oil. Gas chromatography-mass spectrometry analyses indicated safrol as the main compound of the volatile oil (39%). The results confirm and authenticate the use of its leaves in folk medicine. Furthermore, safrol is economically important as the starting material for hemisynthesis of several products. The antimicrobial activity of the essential oil was studied which showed promising activity against environmental microorganisms as well as anti-inflammatory activity.
Optimizing Deep Learning Architecture for ST Elevation Detection in Myocardial Infarction Diagnosis
Creators: name: Hamed, Sohayla
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 420308
subject: Health informatics and information systems

description: Myocardial infarction(MI) refers to the ischemic death of myocardial tissue, thick middle cardiac tissue. The most common manifestation of MI is acute coronary syndrome(ACS), which is usually diagnosed by the elevation of the ST segment of an electrocardiogram(ECG). This is called ST-elevation myocardial infarction(STEMI). STEMI causes the deadliest heart attacks and increases the risk of heart arrhythmia and heart failure. Existing medical diagnoses using deep learning techniques involve the categorization of ECG delineations into different feature maps to detect disease-causing abnormalities. This can be done by training a deep neural network on transforming separate windows of the best ECG features. The features are appointed based on their relevance to the diagnosed disease or class of diseases. Severe episodes of ischemic heart disease and STEMI contribute to many heart attack deaths. Immediate ST?elevation heart attacks only have subtle ECG signs, which increases the likelihood of physician error. This paper aims to classify different heart attack-causing cardiovascular phenomena classes by applying feature extraction, transforms, and convolutional neural networks (CNNs). This method contributes to decreasing errors caused by patterns that may be unnoticeable by physicians. This paper proposes a diagnosis model that optimizes the search for the unhealthy class using a population-based optimization method called Particle Swarm Optimization (PSO). The model utilizes ECG data to extract features, assesses their reliability, stores the enhanced features, and feeds them into an optimized CNN to produce a desirable operational characteristic for the unhealthy class. The results of this work perform experiments on different propositions of the same general architecture, such as ConvNetQuake and ResNet50, as a comparative. The channel-split PSO ResNet50 has achieved the maximum results concerning an accuracy of 98.67%, a precision of 88%, an F1 score of 60%, and a relative operational characteristic (ROC) of 60%. This provides insights into enhancing cardiovascular health monitoring and diagnosis.
Carolinaia cyperi Ainslie 1915
Creators: name: Simbaqueba, Ronald
name: Serna, Francisco
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Aphididae
Carolinaia
Carolinaia cyperi

description: Carolinaia cyperi Ainslie, 1915 (Fig. 2)
Longitud 1,0 a 1,5 mm. Adultas ápteras, de color negro o verde negruzco, con lustre metálico; cuerpo uniformemente esclerosado; superficie de la cabeza, tórax y abdomen rugosa (Fig. 2a y 2c). antena de seis antenómeros y de 0,5 a 0,6 veces el cuerpo; I, II, V y VI oscuros, III y IV pálidos. Filamento terminal 1,9 a 2,5 veces la longitud del tramo proximal. Aladas, con siete a once rinarios secundarios en antenómero III (Fig. 2b), y cero o uno en el IV. Rostro con longitud que alcanza las coxas anteriores o medias. Sifúnculos ligeramente claviformes (Fig. 2d). Cauda triangular o digitiforme, sin constricción (Fig. 2e), 0,3 a 0,45 la longitud de los sifúnculos, con cuatro setas (Ainslie 1915, Holman 1974, Blackman y Eastop 1994, 2006).
description: Published as part of Simbaqueba, Ronald & Serna, Francisco, 2021, Áfidos (Hemiptera: Aphididae) de Colombia, con nuevos registros para el norte de Sudamérica, pp. 1-27 in Caldasia 43 (1) on page 14, DOI: 10.15446/caldasia.v41n3.77979, http://zenodo.org/record/15265235
Lambda-CDM halo density profiles: where do actual halos converge to NFW ones?
Creators: name: Gentile, G.
name: Tonini, C.
name: Salucci, P.
Publisher: name: Swinburne
Year: 2024

description: We present an analysis of 37 high-quality extended rotation curves that highlight the existence of a new discrepancy (or a new aspect of an old discrepancy) between the density profiles predicted by the lambda cold dark matter (lambda-CDM) theory and the actual distribution of dark matter in galaxies. We compare the predicted face-value density vs. enclosed mass relationship, at large distances, to the observational data at the last measured radii of the rotation curves and in two whole rotation curves of high quality. A further analysis is performed by studying a relation, inbuilt in lambda-CDM, that links, at radius R, the enclosed halo mass MNFW(R) and its density ρ(R) in a way that is independent of the mass of the virialised object. We find that the predicted density vs. enclosed mass relationship has a systematic offset with respect to the observational data. In test case extended rotation curves, at their last measured point, the predicted NFW densities are up to a factor 3 lower than those derived from the kinematics. Moreover, the abovementioned relation, inbuilt in lambda-CDM, does not hold for the objects of our sample. Such a new outer discrepancy is different and maybe complementary with respect to the core/cusp issue, for which the NFW densities turn out to be higher than those observed, and it seems to imply a global mass rearrangement of a pristine NFW-lambda-CDM halo.
Further in vitro evaluation of cytotoxicity of the marine natural product derivative 4′-leucine-avarone
Creators: name: Pejin, Boris
name: Iodice, Carmine
name: Tommonaro, Giuseppina
name: Bogdanovic, Gordana
name: Kojic, Vesna
name: Rosa, Salvatore De
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: The cytotoxicity of 4′-leucine-avarone, amino derivative of the sponge Dysidea avara secondary metabolite avarone, was evaluated by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay in vitro against seven human solid tumours for the first time. The compound tested induced dose-dependent cytotoxic response in all cancer cells showing better activity towards the lung A-549 and colon HT-29 cell lines (IC50 7.40 μM and 9.62 μM, respectively) than towards the breast adenocarcinoma ER positive MCF-7 and ER negative MDA-MB-231 cells (IC50 11.64 μM and 17.31 μM, respectively), the prostate adenocarcinoma PC-3 and epiteloid cervix carcinoma HeLa cells (IC50 14.24 μM and 15.54 μM, respectively). No toxicity was found towards the foetal lung fibroblast MRC-5 cell line at the concentrations used. According to experimental data obtained, the sesquiterpenoid quinone structure of avarone may inspire development of new drug-like substances with improved cytotoxicity on lung cancer in humans.
New cytotoxic spirostane saponin and biflavonoid glycoside from the leaves of Acacia saligna (Labill.) H.L. Wendl.
Creators: name: Gedara, Sahar R.
name: Galala, Amal A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: New naturally occurring spirostane saponin (25S)-5β-spirostan-3β-yl-3-O-β-d-xylopyranosyl(1 → 3)-O-β-d-xylopyranosyl(1 → 4)-β-d-galactopyranoside (6) and biflavonoid glycoside myricetin-3-O-rhamnoside (C7-O-C7) myricetin-3-O-rhamnoside (4) along with a series of known compounds erythrodiol (1), 3β-O-trans-p-coumaroyl-erythrodiol (2), quercetin-3-O-α-l-rhamnoside (3) and myricetin-3-O-α-l-rhamnoside (5) were separated from the leaves of Acacia saligna (Labill.), H.L. Wendl. Compounds 1 and 2 were separated for the first time from genus Acacia. The structures of compounds 1–6 were established on the basis of extensive 1D and 2D NMR spectroscopic techniques in combination with EI-MS and HR-ESI-MS. These compounds were screened for their antioxidant and cytotoxic activities against HEPG2 (liver cancer) cell line and significant results were obtained.
Wikidata: the potential of structured data to enable applications such as Histropedia
Creators: name: Evans, Navino
Publisher: name: ISKO UK
Year: 2015
Subjects: Wikidata
Structured data
DBpedia

description: Despite the vast number of uses for Wikipedia, you still can’t ask it even simple questions like “who is the Mayor of London?” – Computers simply do not understand the unstructured data. Wikidata is a ground-breaking new Wikimedia project that aims to tackle this problem and many others, by making the sum of all human knowledge machine-readable. It will provide aback end to Wikipedia, potentially allowing a single change in Wikidata to correct and improve information represented in multiple places in Wikipedia, across all language versions.In this presentation I will give a basic overview of how Wikidata works, including information about how the data is structured and connected to other resources on the internet, as well as the methods being used to collect and organize the data. I will also highlight the major similarities and differences between Wikidata and the already widely used DBpedia.Finally, I will go on to explain the implications of Wikidata’s development for the future of Wikipedia and the rest of the web, giving examples of applications that have already been built upon data from Wikidata such as Histropedia, which aims to visualize the sum of all knowledge using interactive timelines.
The native production of the sesquiterpene isopterocarpolone by Streptomyces sp. RM-14-6
Creators: name: Shaaban, Khaled A.
name: Shanteri Singh
name: Elshahawi, Sherif I.
name: Xiachang Wang
name: Ponomareva, Larissa V.
name: Sunkara, Manjula
name: Copley, Gregory C.
name: Hower, James C.
name: Morris, Andrew J.
name: Madan K. Kharel
name: Thorson, Jon S.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: We report the production, isolation and structure elucidation of the sesquiterpene isopterocarpolone from an Appalachian isolate Streptomyces species RM-14-6. While isopterocarpolone was previously put forth as a putative plant metabolite, this study highlights the first native bacterial production of isopterocarpolone and the first full characterisation of isopterocarpolone using 1D and 2D NMR spectroscopy and HR-ESI mass spectrometry. Considering the biosynthesis of closely related metabolites (geosmin or 5-epiaristolochene), the structure of isopterocarpolone also suggests the potential participation of one or more unique enzymatic transformations. In this context, this work also sets the stage for the elucidation of potentially novel bacterial biosynthetic machinery.
Structure Functions and Parton Densities: a Session Summary
Creators: name: Nachman, Benjamin
name: Wichmann, Katarzyna
name: Zurita, Pia
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: 530 Physik

description: Studies of fragmentation and parton density functions are a core component of research in high energy particle and nuclear physics. These quantities are inherently interesting as a probe of the quantum nature of the strong force and are also essential ingredients to additional studies in high energy scattering experiments. These proceedings provide an overview of the state of the art in this area, as presented at the Deep-Inelastic Scattering Conference in the Spring of 2021.
The impact of mergers on relaxed x-ray clusters III: effects on compact cool cores
Creators: name: Poole, Gregory B.
name: Babul, Arif
name: McCarthy, Ian G.
name: Sanderson, Adam J. R.
name: Fardal, Mark A.
Publisher: name: Swinburne
Year: 2024

description: We use the simulations presented in Poole et al. to examine the effects of mergers on the properties of cool cores in X-ray clusters. Motivated by recent Chandra and XMM–Newton observations, we propose a scheme for classifying the morphology of clusters based on their surface brightness and entropy profiles. Three dominant morphologies emerge: two hosting compact cores and central temperatures which are cool [CCC (compact cool core) systems] or warm [CWC (compact warm core) systems] and one hosting extended cores which are warm [EWC (extended warm core) systems]. In the cases we have studied, CCC states are disrupted only after direct collisions with merging cluster cores. This can happen in head-on collisions or during second pericentric passage in off-axis mergers. By the time they are relaxed, our remnant cores have generally been heated to warm core (CWC or EWC) states but subsequently recover CCC states by the end of the simulation. The only case resulting in a long-lived EWC state is a slightly off-axis 3:1 merger for which the majority of shock heating occurs during the accretion of a low-entropy stream formed from the disruption of the secondary's cool core. Since tdyn≪tcool for all our relaxing merger remnant cores, compression prevents their core temperatures from falling until after they relax to the compact states allowed by their remnant central entropies. This naturally explains the population of relaxed CWC systems observed in recent Chandra and XMM–Newton observations with no need to invoke active galactic nuclei feedback. The morphological segregation in the Lx–Tx scaling relation noted by McCarthy et al. is qualitatively reflected in the results of our mergers as well. However, none of the cases we have studied produces systems with sufficiently high central entropies to account for the most underluminous EWC systems observed. Lastly, mergers do not efficiently mix the intracluster medium in our simulations. As a result, merging systems which initially host central metallicity gradients do not yield merger remnants with flat metallicity profiles. Taken together, these results suggest that once formed, compact core systems are remarkably stable against disruption from mergers. It remains to be demonstrated exactly how the sizable observed population of extended core systems was formed.
title: Indigenous peoples and biodiversity law in Ecuador: An interview with Daqui Lema Maldonado from the Kichwa People of Otavalo
Creators: name: Maldonado, Daqui Lema
name: Tomaselli, Alexandra
Publisher: name: Fachinformationsdienst für internationale und interdisziplinäre Rechtsforschung
Year: 2020
Subjects: subject: 341

description: Völkerrechtsblog
Determination of n-alkane constituents and their phenological variation in the epicuticular wax of mature leaves of Nyctanthes arbor-tristis L.
Creators: name: Irani Biswas
name: Sushobhan Ukil
name: Ambarish Mukherjee
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: The present communication is a first-time report on the analyses of n-alkane profile of epicuticular wax extracted from the mature leaves of Nyctanthes arbor-tristis L. during a calender year. The composition of n-alkanes revealed hentriacontane (n-C31), tritriacontane (n-C33), tetratriacontane (n-C35) and nonacosane (n-C29) as the major constituents with tritriacontane (n-C33) being the dominant constituent. The cumulative percentage of these four odd-numbered alkanes also showed phenological variation being highest during the fruit ripening stage (average value 63.29%) followed by the flowering stage (mean value 60.74%). The values remained moderate on an average of 54.31% for the rest of the year. This study also confirms the xerophytic feature of the plant having higher proportion of longer carbon chain n-alkanes greater than C31 (dominant peaks are of C33 and C35).
Determination of the rapidity evolution kernel from Drell-Yan data at low transverse momenta
Creators: name: Hautmann, F.
name: Scimemi, I.
name: Vladimirov, Alexey
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: 530 Physik

description: We report recent results on the extraction of the rapidity evolution kernel for Sudakov processes from experimental measurements of Drell-Yan (DY) transverse momentum distributions. We discuss the role of high-precision Large Hadron Collider (LHC) data, and illustrate the interplay of this analysis with transverse momentum dependent and collinear parton density functions.