cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
РОЛЬ МЕДСЕСТР ПЕРВИЧНОЙ ПОМОЩИ В ПРОФИЛАКТИКЕ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ
Creators: name: Мирдадаева, Дилфуза
Publisher: name: Zenodo
Year: 2025

description: Медсестры первичной помощи играют важную роль в профилактике сердечно-сосудистых заболеваний (ССЗ), выступая в качестве поставщиков медицинских услуг на передовой с уникальными возможностями для взаимодействия с пациентами и их вмешательства. Поскольку на долю ССЗ приходится около 31% глобальной смертности, роль медсестер первичной помощи становится все более важной в стратегиях профилактики. В этом исследовании изучаются эффективность и масштаб вмешательств под руководством медсестер в профилактику ССЗ в условиях первичной медико-санитарной помощи. Исследование показало, что медсестры, прошедшие специализированную подготовку по профилактике сердечно-сосудистых заболеваний, достигли значительно лучших результатов для пациентов по сравнению с теми, кто не прошел такую подготовку, внедрение клиник под руководством медсестер привело к 40%-ному снижению предотвратимых сердечно-сосудистых событий среди пациентов с высоким риском.
Higher Order Modes and Dampers for the LHC Double Quarter Wave Crab Cavity
Creators: name: Mitchell, James
Publisher: name: Lancaster University
Year: 2019

description: This thesis initially investigates the DQW crab cavity HOM couplers manufactured for tests in the Super Proton Synchrotron (SPS) at CERN and proposed for the HL-LHC upgrade. The coupler’s are modelled using equivalent circuit analysis and ‘test-boxes’ are used to measured each of the six HOM couplers for the SPS test. The DQW crab cavity’s impedance spectra and resulting HOM power generation as a result of excitation by the high-current HL-LHC beam is quantified. Following this, HOM measurements are used to characterise the deviations from the simulated case. Evaluation of the DQW’s impedance spectra and stochastic analysis of the foreseeable HOM power generation in the HL-LHC highlights potential issues with the HOMs. To mitigate the issues, a re-design of the HOM coupler is presented; The impedance and HOM power are quantified and benchmarked. In parallel, a new ‘quarter wave’ rejection filter is designed and evaluated. The operation of the HOM couplers in the presence of the operating electromagnetic field is assessed, quantifying thermal and multipacting behaviour. Finally, first measurements of crab cavity HOMs with proton bunches are presented and compared with simulations. The measurements are used to evaluate the accuracy of the methods used to calculate impedance and HOM power. Several conclusions feed-back into ancillary design and acceptance criteria for future manufacture.
A programmable three-qubit superconducting processor with all-to-all connectivity
Creators: name: Roy, Tanay
name: Hazra, Sumeru
name: Kundu, Suman
name: Chand, Madhavi
name: Patankar, Meghan P.
name: Vijay, R.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Superconducting circuits are at the forefront of quantum computing technology because of the unparalleled combination of good coherence, fast gates and flexibility in design parameters. The majority of experiments demonstrating small quantum algorithms in the superconducting architecture have used transmon qubits and transverse qubit-qubit coupling. However, efficient universal digital computing has remained a challenge due to the fact that majority of the state-of-art architectures rely on nearest-neighbor coupling in one or two dimensions. The limited connectivity and the availability of only two-qubit entangling gates result in inefficient implementation of algorithms with reduced fidelity. In this work, we present a programmable three-qubit processor, nicknamed "trimon", with strong all-to-all coupling and access to native three-qubit gates. We implement three-qubit version of various algorithms, namely Deutsch-Jozsa, Bernstein-Vazirani, Grover's search and the quantum Fourier transform, to demonstrate the performance of our processor. Our results show the potential of the trimon as a building block for larger systems with enhanced qubit-qubit connectivity.
description: 11 pages, 7 figures, 4 tables
Schwinger-Dyson Equation for Supersymmetric Yang-Mills Theory
Creators: name: Itoyama, Hiroshi
name: Takashino, Hiroyuki
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study our Schwinger-Dyson equation as well as the large $N_{c}$ loop equation for supersymmetric Yang-Mills theory in four dimensions by the N=1 superspace Wilson-loop variable. We are successful in deriving a new manifestly supersymmetric form in which a loop splitting and joining are represented by a manifestly supersymmetric as well as supergauge invariant operation in superspace. This is found to be a natural extension from the abelian case. We solve the equation to leading order in perturbation theory or equivalently in the linearized approximation, obtaining a desirable nontrivial answer. The super Wilson-loop variable can be represented as the system of one-dimensional fermion along the loop coupled minimally to the original theory. One-loop renormalization of the one-point Wilson-loop average is explicitly carried out, exploiting this property. The picture of string dynamics obtained is briefly discussed.
description: 47 pages, latex
CQ UMa – a slowly accelerating cool magnetic CP star
Creators: name: Mikulasek, Zdenek
name: Janik, Jan
name: Krticka, Jiri
name: Zejda, Miloslav
name: Paunzen, Ernst
name: Romanyuk, Iosif
name: Yakunin, Ilya
name: Hummerich, Stefan
name: Bernhard, Klaus
name: David-Uraz, Alexandre
name: Shultz, Matthew
Publisher: name: Zenodo
Year: 2021
Subjects: Stars individual: CQ UMa
CP stars
Photometry
Stars magnetic field

description: CQ UMa = HD 119213 is a member of an exclusive SrCrEu star club showing significant variability in the c1 index, expressing the Balmer jump's height. The cause of the light variability of those cool mCP stars is not yet known. The group includes, e.g., CS Vir, VV Scl, BR Cru, and BS Cir, which is known to change its period. We are preparing a comprehensive study of these stars, most of which have sufficiently high-quality TESS photometry.
 58954 individual photometric, spectroscopic, and magnetic observations of CQ UMa obtained during the last 50 years helped us reveal a marginal acceleration of its rotation period as $\dot{P}=10(3)\times10^{-10}$, which is by far the slightest proven period change in mCPs. The case of CQ UMa suggests that the rotation period variability affects all types and mass categories of mCP stars and may not be as rare as we thought so far.
Black Hole-Wormhole transition in (2+1) Einstein -- anti-de Sitter Gravity Coupled to Nonlinear Electrodynamics
Creators: name: Cañate, Pedro
name: Breton, Nora
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper we present two results in $(2+1)$ gravity coupled to nonlinear electrodynamics. First it is determined the general form of the electromagnetic field tensor in $(2+1)$ gravity coupled to nonlinear electrodynamics in stationary cyclic spacetimes. Secondly, it is determined a family of exact solutions in $(2+1)$ gravity sourced by a nonlinear electromagnetic field. The solutions are characterized by five parameters: mass $M$, angular momentum $J$, cosmological constant $Λ$ and two electromagnetic charges, $q_α$ and $q_β$. Remarkably, the solution can be interpreted as a traversable wormhole, provided the fulfillment of certain inequalities by the characteristic parameters; fine tunning of the cosmological constant leads to an extreme black hole, whereas by switching off one of the electromagnetic charges, we obtain the Bañados-Teitelboim-Zanelli (BTZ) black hole.
description: Typos corrected. Published in Physical Review D. arXiv admin note: text overlap with arXiv:1307.6655 by other authors
The quark condensate in the GMOR relation
Creators: name: Langfeld, Kurt
name: Kettner, Christiane
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The quark condensate which enters the Gell-Mann-Oakes-Renner (GMOR) relation, is investigated in the framework of one-gluon-exchange models. The usual definition of the quark condensate via the trace of the quark propagator produces a logarithmic divergent condensate. In the product of current mass and condensate, this divergence is precisely compensated by the bare current mass. The finite value of the product in fact does not contradict the relation recently obtained by Cahill and Gunner. Therefore the GMOR relation is still satisfied.
description: 8 pages LaTeX, no figures. minor modifications and additional comments on the validity range of our main result
Benefit of using interaction effects for the analysis of high-dimensional time-response or dose-response data for two-group comparisons
Creators: name: Duda, Julia C.
name: Drenda, Carolin
name: Kästel, Hue
name: Rahnenführer, Jörg
name: Kappenberg, Franziska
Publisher: name: TU Dortmund
Year: 2023
Subjects: subject: Biotechnology
subject: Functional genomics
subject: Genomics
subject: 310

description: High throughput RNA sequencing experiments are widely conducted and analyzed to identify differentially expressed genes (DEGs). The statistical models calculated for this task are often not clear to practitioners, and analyses may not be optimally tailored to the research hypothesis. Often, interaction effects (IEs) are the mathematical equivalent of the biological research question but are not considered for different reasons. We fill this gap by explaining and presenting the potential benefit of IEs in the search for DEGs using RNA-Seq data of mice that receive different diets for different time periods. Using an IE model leads to a smaller, but likely more biologically informative set of DEGs compared to a common approach that avoids the calculation of IEs.
description: Scientific reports;13
The Influence of Robot Social Behaviors on Second Language Learning in Preschoolers
Creators: name: Yin, Jun
name: Guo, Wenjiao
name: Zheng, Wei
name: Ren, Mingyu
name: Wang, Simin
name: Jiang, Yingdong
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: The use of social robots has flourished in the educational field. Using them in education appropriately entails considering whether robot social behaviors influence language learning outcomes and have additive influences on the outcomes of language learning. In this study, we used a social robot (i.e., Alpha Mini) to teach Chinese preschool children (N = 83, recruited from a preschool; aged 6–7 years) new English words; it had the pitch of a human boy, and the words’ referents were displayed on a tablet. During one learning session, the robot demonstrated one of several types of social behavior: verbal behavior (i.e., asking children to look at this robot), gestural behavior (i.e., pointing to the word’s referent), both verbal and gestural behaviors, and control (i.e., purely saying target words to the children). Children were randomly assigned to one of four conditions. Their vocabulary learning outcomes were measured by pre- and posttests of the children’s vocabulary of the target words. Our results show that the learning outcome in each type of social behavior was greater than zero, suggesting that any type of robot social behavior benefits word learning. Importantly, when robot social behavior included verbal demonstrations, the preschoolers learned more vocabulary than when the robot displayed other social behaviors (i.e., control and gestural behavior); however, gestural behavior showed no greater learning outcomes than the control condition. Hence, the efficacy of robot tutoring in preschoolers’ second language learning depends upon a robot’s social behavior, and social verbal behavior is the most effective behavior in increasing learning gains. Therefore, to achieve better learning outcomes, social verbal behavior should be critically considered to enhance robots’ tutoring function.
HIF1α-siRNA and gemcitabine combination-based GE-11 peptide antibody-targeted nanomedicine for enhanced therapeutic efficacy in pancreatic cancers
Creators: name: Chengjie Lin
name: Zhigao Hu
name: Guandou Yuan
name: Huizhao Su
name: Yonglian Zeng
name: Guo, Zhenya
name: Fudi Zhong
name: Keqing Jiang
name: Songqing He
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Pancreatic cancer is one of the deadliest cancers across the world with an average 5-year survival rate of less than <6%. In this study, gemcitabine (GEM) and HIF1α-siRNA loaded GE-11 peptide conjugated liposome was successfully prepared and evaluated for its antitumor efficacy in pancreatic cancer cells. The GE11 increased the targeting specificity of liposome carrier and increased the intracellular concentrations in the cancer cells. Furthermore, synergistic combination of GEM and HIF1a-siRNA exhibited remarkable improvement in the declining of cancer cell proliferations. siRNA could effectively decrease the expression of HIF1a gene in the cancer cells. Importantly, GE-11 peptide-conjugated GEM/siRNA-loaded liposomes (GE-GML/siRNA) increased the total amount of apoptosis cells with higher proportion of cells in late apoptosis phase. GE-GML induced remarkable apoptosis of cancer cells and induced chromatin condensation and nuclear fragmentation which are considered to be typical features of apoptosis and cell death. GE-GML/siRNA showed a significant reduction in the tumour burden suggesting the superior anticancer efficacy of this formulation. GE-GML/siRNA showed four-fold reduction in tumour compared to control and two-fold reduction compared to GE-GML, respectively. Overall, present work lays foundation for the combination of GEM and HIF1a-siRNA loaded in a targeted nanocarrier system as a unique therapeutic option in pancreatic cancer treatment.
Constraints on MeV dark matter using neutrino detectors and their implication for the 21-cm results
Creators: name: Klop, Niki
name: Ando, Shin'ichiro
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The recent results of the EDGES collaboration indicate that during the era of reionization, the primordial gas was much colder than expected. The cooling of the gas could be explained by interactions between dark matter (DM) and particles in the primordial gas. Constraints from cosmology and particle experiments indicate that this DM should be light ($\sim$10-80 MeV), carry a small charge ($ε\sim 10^{-6}$-$10^{-4}$), and only make up a small fraction of the total amount of DM. Several constraints on the DM parameter space have already been made. We explore the yet unconstrained region in the case that the milli-charged DM makes up for $\sim$2\% of the total dark matter, through the scenario in which this DM annihilates only into mu and tau neutrinos. We set upper limits on the annihilation cross section using the Super-Kamiokande data, and predict the limits that could be obtained through Hyper-Kamiokande, JUNO and DUNE. We find that data from Super-Kamiokande is not yet able to constrain this model, but future experiments might be. We furthermore explore DM annihilation into solely neutrinos in general, giving an update of the current limits, and predict the limits that could be placed with future experiments.
description: 6 pages, 6 figures
title: [Zweiteilige Sammelhandschrift]; I: 1517-1519; II: Anfang 16. Jahrhundert
title: (VD) Kurze Auslegung von Io. 4,32. (1r) [Alphabetum malorum et bonorum]. (22r) Tractatus vel Sermones de diversis. (70r) Sermones de diversis. (100r) Quaestiones XXIII. (117v) Quaestiones VI. (124r) Occasio dicendi in mensa. (126r) Collaciones tam pro religiosis quam pro aliis. (172r) Sermones de tempre et de sanctis. (189r) [Formulae salutationis]. (190v) [De praeceptis et mandatis dei]. (200v, 214r) Notae et excerpta praedicabilia. (215r) Declarationes iuris.
titleType: Subtitle
Creators: name: (:Unav)
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2024

description: Datierende und lokalisierende Schreibervermerke (48v, 54v, 69v, 75r, 79v, 84v, 99v, 117r, 123v, 129v, 194r und 199v)
description: Papier - Eilige Kursive von einer Haupthand (Schreiber: Johannes Macheisen (75r, 84v, 91r, 123v und 129v)), Lemata in geformter Bastarda, teilweise rubriziert, Nachträge und Randzusätze von mehreren Händen
description: Beschädigter Pappband mit braunem Lederbezug und Hirschjagdrolle, zwei Schließen fehlen
description: Vorbesitz: Bibliothek des Franziskanerklosters Landshut; Stempel der Universitätsbibliothek Landshut (1r); Stempel der Universitätsbibliothek München (Iv)
description: Kurzaufnahme einer Handschrift = 8° Cod.ms. 60
Sphingofungins G and H: new five-membered lactones from Aspergillus penicilliodes Speg.
Creators: name: Zhang, Han
name: Zhu, Hong-Tao
name: Wang, Dong
name: Yang, Chong-Ren
name: Zhang, Ying-Jun
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Two new sphingofungins G (1) and H (2) with a five-membered lactone ring were identified from the solid-state fermentation of Aspergillus penicilliodes Speg., a dominant microorganism isolated previously from the post-fermentation of ripe Pu-er tea, together with six known metabolites. Their structures were elucidated by extensive spectroscopic methods. All of them were isolated from the mycelia culture of A. penicilliodes for the first time. The known compound, trypacidin, exhibited potent cytotoxities against five human cancer cell lines, e.g. myeloid leukemia HL-60, lung cancer A-549, hepatocellular carcinoma SMMC7721, breast cancer MCF-7, and colon cancer SW480, with IC50 values of 0.55, 11.45, 10.95, 3.58, and 3.49 μM, resp., while cisplatin as the positive control, with IC50 values of 8.63, 24.15, 21.99, 27.29, and 23.61 μM, resp.
Fast mean-reversion asymptotics for large portfolios of stochastic volatility models
Creators: name: Hambly, Ben
name: Kolliopoulos, Nikolaos
Publisher: name: arXiv
Year: 2018
Subjects: subject: Probability (math.PR)
subject: Mathematical Finance (q-fin.MF)
subject: Risk Management (q-fin.RM)
subject: FOS: Mathematics
subject: FOS: Economics and business
subject: 60H15 (primary) 41A25, 41A58, 91G80 (secondary)

description: We consider an SPDE description of a large portfolio limit model where the underlying asset prices evolve according to certain stochastic volatility models with default upon hitting a lower barrier. The asset prices and their volatilities are correlated via systemic Brownian motions, and the resulting SPDE is defined on the positive half-space with Dirichlet boundary conditions. We study the convergence of the loss from the system, a function of the total mass of a solution to this stochastic initial-boundary value problem under fast mean reversion of the volatility. We consider two cases. In the first case the volatility converges to a limiting distribution and the convergence of the system is in the sense of weak convergence. On the other hand, when only the mean reversion of the volatility goes to infinity we see a stronger form of convergence of the system to its limit. Our results show that in a fast mean-reverting volatility environment we can accurately estimate the distribution of the loss from a large portfolio by using an approximate constant volatility model which is easier to handle.
description: 37 pages
Models of the Pseudogap State in Cuprates
Creators: name: Sadovskii, M. V.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We review a certain class of ("nearly") exactly solvable models of electronic spectrum of two-dimensional systems with fluctuations of short range order of "dielectric" (e.g. antiferromagnetic) or "superconducting" type, leading to the formation of anisotropic pseudogap state on certain parts of the Fermi surface. The models are based on recurrence procedure for one- and two-electron Green's functions which takes into account of all Feynman diagrams in perturbation series with the use of the approximate Ansatz for higher-order terms in this series. These models can be applied to calculation of spectral density, density of states and conductivity in the normal state, as well as to calculation of some properties of superconducting state.
description: M2S-HTCS-VI Conference Paper, 4 pages, 4 figures, using Elsevier style espcrc2.sty
Topologimeter and the problem of physical interpretation of topology lattice
Creators: name: Grib, A. A.
name: Zapatrin, R. R.
Publisher: name: arXiv
Year: 1995
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The collection of all topologies on the set of three points is studied treating the topology as quantum-like observable. It turns out to be possible under the assumption of the asymmetry between the spaces of bra- and ket-vectors. The analogies between the introduced topologimeter and the Stern-Gerlach experiments are outlined.
description: 14 pages, latex, paper submitted to the International Journal of Theoretical Physics
Centaurea ragusina Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Centaurea
Centaurea ragusina

description: Centaurea ragusina Linnaeus, Species Plantarum 2: 912. 1753.
"Habitat in Creta, Epidauro." RCN: 6595.
 Lectotype (Turland in Jarvis & Turland in Taxon 47: 357. 1998): Herb. Clifford: 422, Centaurea 17 (BM-000647268).
 Current name:  Centaurea ragusina  L. (Asteraceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part C), pp. 370-473 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 402, DOI: 10.5281/zenodo.291971
Multiplexing heralded single-photon in orbital angular momentum space
Creators: name: Liu, Shilong
name: Zhou, Qiang
name: Zhou, Zhiyuan
name: Liu, Shikai
name: Li, Yinhai
name: Li, Yan
name: Guo, Guangcan
name: Shi, Baosen
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Heralded single-photon source (HSPS) with competitive single photon purity and indistinguishability has become an essential resource for photonic quantum information processing. Here, for the first time, we proposed a theoretical regime to enhance heralded single-photons generation by multiplexing the degree of the freedom of orbital angular momentum (OAM) of down-converted entangled photon pairs emitted from a nonlinear crystal. Experimentally, a proof-of-principle experiment has been performed through multiplexing three OAM modes. We achieve a 47$\%$ enhancement in single photon rate. A second-order autocorrelation function $g^{(2)}(0)<0.5$ ensures our multiplexed heralded single photons with good single photon purity. We further indicate that an OAM-multiplexed HSPS with high quality can be constructed by generating higher dimensional entangled state and sorting them with high efficiency in OAM space. Our avenue may approach a good HSPS with the deterministic property.
description: 8 pages and 5 figures.To appear in PRA
Does Playing Cooperative Mobile Games Facilitate Social Interaction and Positive Affect in Middle Childhood?
Creators: name: Iplikci, Ayse Busra
name: Gunaydin, Gul
name: Selcuk, Emre
name: Eren, Yavuz
name: Krasniqi, Lindon
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: The current study examined the effect of a cooperative (vs. a non-cooperative solitary) mobile game on social behaviors and positive affect during gameplay in middle childhood. In a within-participants experimental design, groups of fifth graders (ages from 10 to 12) played in counterbalanced order cooperative and solitary versions of a cooking game developed for tablets. Our findings showed that children who played the cooperative (vs. solitary) mobile game engaged in more positive and neutral conversations during gameplay. They also sought and received more help from peers and displayed greater positive affect during cooperative (vs. solitary) gaming. Finally, they preferred the cooperative mobile game to the otherwise identical solitary game after playing both games. Overall, these findings provide the first experimental evidence of the social and affective benefits of cooperative mobile gaming in middle childhood.
Sphingofungins G and H: new five-membered lactones from Aspergillus penicilliodes Speg.
Creators: name: Zhang, Han
name: Zhu, Hong-Tao
name: Wang, Dong
name: Yang, Chong-Ren
name: Zhang, Ying-Jun
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Two new sphingofungins G (1) and H (2) with a five-membered lactone ring were identified from the solid-state fermentation of Aspergillus penicilliodes Speg., a dominant microorganism isolated previously from the post-fermentation of ripe Pu-er tea, together with six known metabolites. Their structures were elucidated by extensive spectroscopic methods. All of them were isolated from the mycelia culture of A. penicilliodes for the first time. The known compound, trypacidin, exhibited potent cytotoxities against five human cancer cell lines, e.g. myeloid leukemia HL-60, lung cancer A-549, hepatocellular carcinoma SMMC7721, breast cancer MCF-7, and colon cancer SW480, with IC50 values of 0.55, 11.45, 10.95, 3.58, and 3.49 μM, resp., while cisplatin as the positive control, with IC50 values of 8.63, 24.15, 21.99, 27.29, and 23.61 μM, resp.
Multiparton Interactions in Photoproduction at HERA
Creators: name: Butterworth, J. M.
name: Forshaw, J. R.
name: Seymour, M. H.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The high energy photoproduction of jets is being observed at the ep collider, HERA. It may be that the HERA centre-of-mass energy is sufficiently large that the production of more than one pair of jets per ep collision becomes possible, owing to the large number density of the probed gluons. We construct a Monte Carlo model of such multiparton interactions and study their effects on a wide range of physical observables. The conclusion is that multiple interactions could have very significant effects upon the photoproduction final state and that this would for example make extractions of the gluon density in the photon rather difficult. Total rates for the production of many (i.e. > 2) jets could provide direct evidence for the presence of multiple interactions, although parton showering and hadronization significantly affect low transverse energy jets.
description: 21 pages, 8 figures included
Antibiotic use and resistance in Belgium: the impact of two decades of multi-faceted campaigning
Creators: name: Bruyndonckx, R.
name: Coenen, S.
name: Hens, N.
name: Vandael, E.
name: Catry, B.
name: Goossens, H.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology

description: Objective: To present an overview of almost two decades of multi-faceted campaigning by the Belgian Antibiotic Policy Coordination Committee (BAPCOC) and partners, and its impact on public and prescribers’ awareness, outpatient antibiotic use, its cost and antimicrobial resistance in Belgium.Methods: Awareness of both public and prescribers was assessed through pre- and post-campaign interviews and surveys. Outpatient antibiotic use was evaluated using national reimbursement data expressed in number of defined daily doses and packages (a good proxy for treatments) per 1000 inhabitants per day (DID and PID, respectively) from July 1997 to June 2018. Its cost was studied using the same data expressed in number of euros per 1000 inhabitants per day. Antimicrobial resistance was evaluated between 1986 and 2017 using national data on the proportion of Streptococcus pneumoniae isolates not susceptible to penicillins, macrolides and tetracyclines.Results: Antibiotic awareness improved significantly, with general practitioners preferred by 87.5% of respondents as source of information. The Belgian outpatient antibiotic use has decreased by 12.8% in DID and by 42.8% in PID in the 2017-2018 winter compared to the winter before the start of its public awareness campaigns (1999-2000). This evolution coincided with decreasing costs for antibiotics and decreasing antimicrobial resistance. Despite multi-faceted campaigning, outpatient antibiotic use and use of broad-spectrum antibiotics, especially fluoroquinolones and amoxicillin with clavulanic acid, are still high in Belgium.Conclusion: Almost two decades of multi-faceted campaigning coincide with improvements in antibiotic awareness among the public and prescribers, outpatient antibiotic use and resistance. Nevertheless, additional efforts are needed to reach the targets set in BAPCOC’s national action plan 2014-2019. Therefore, a new national action plan was developed for 2020-2024 using a One Health approach.
Evolution of spatio-kinematic structures in star-forming regions: are Friends of Friends worth knowing?
Creators: name: Parker, Richard J.
name: Wright, Nicholas J.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The Friends of Friends algorithm identifies groups of objects with similar spatial and kinematic properties, and has recently been used extensively to quantify the distributions of gas and stars in young star-forming regions. We apply the Friends of Friends algorithm to $N$-body simulations of the dynamical evolution of subvirial (collapsing) and supervirial (expanding) star-forming regions. We find that the algorithm picks out a wide range of groups (1 -- 25) for statistically identical initial conditions, and cannot distinguish between subvirial and supervirial regions in that we obtain similar mode and median values for the number of groups it identifies. We find no correlation between the number of groups identified initially and either the initial or subsequent spatial and kinematic tracers of the regions' evolution, such as the amount of spatial substructure, dynamical mass segregation, or velocity dispersion. We therefore urge caution in using the Friends of Friends algorithm to quantify the initial conditions of star formation.
description: 12 pages, 8 figures, accepted for publication in MNRAS
The Experience of stroke in Malaysia
Creators: name: Mairami, Fatima Fanna
Publisher: name: Monash University
Year: 2019
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Stroke is a leading cause of death and disability globally. A third of people who have experienced stroke are left with a permanent disability, thus, it is imperative to investigate and understand the lived experiences of stroke from the perspective of the survivor. This study aims to expand on the experience of being a stroke survivor. The study employed an ethnographic approach to investigating the experiences of stroke survivors in rural Peninsular Malaysia. The study highlights the contextual complexity of life with stroke and offers a robust and effective public health strategy for the management of stroke.
Mass Generation in the Supersymmetric Nambu--Jona--Lasinio Model in an External Magnetic Field
Creators: name: Shovkovy, Igor A.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The mass generation in the (3+1)-dimensional supersymmetric Nambu-Jona-Lasinio model in a constant magnetic field is studied. It is shown that the external magnetic field catalyzes chiral symmetry breaking.
description: LaTeX file, 6 pages. Talk given at the International Seminar dedicated to the memory of Dmitrij Volkov "Supersymmetry and Quantum Field Theory", Kharkov, Ukraine, January 5-7, 1997
Acroptilon repens
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Acroptilon
Acroptilon repens

description: Centaurea repens Linnaeus, Species Plantarum, ed. 2, 2: 1293. 1763.
"Habitat in Oriente." RCN: 6605.
Type not designated.
Original material: Herb. Linn. No. 1030.34 (LINN).
 Current name:  Acroptilon repens  (L.) DC. (Asteraceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part C), pp. 370-473 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 402, DOI: 10.5281/zenodo.291971
Magnetic properties of doped Heisenberg chains
Creators: name: Frahm, Holger
name: Slavnov, Nikita A.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The magnetic susceptibility of systems from a class of integrable models for doped spin-$S$ Heisenberg chains is calculated in the limit of vanishing magnetic field. For small concentrations $x_h$ of the mobile spin-$(S-1/2)$ charge carriers we find an explicit expression for the contribution of the gapless mode associated to the magnetic degrees of freedom of these holes to the susceptibility which exhibits a singularity for $x_h\to0$ for sufficiently large $S$. We prove a sum rule for the contributions of the two gapless magnetic modes in the system to the susceptibility which holds for arbitrary hole concentration. This sum rule complements the one for the low temperature specific heat which has been obtained previously.
description: Latex2e, 22 pp, 3 figures included
title: ADCO, Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Cart. 181 (11 H 754), 165 folios, f. 0183
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 181 (11 H 754), 165 folios, f. 0183, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 181 (11 H 754), 165 folios, f. 0183, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
The 1989 and 2015 outbursts of V404 Cygni: a global study of wind-related optical features
Creators: name: Sánchez, D. Mata
name: Muñoz-Darias, T.
name: Casares, J.
name: Charles, P. A.
name: Padilla, M. Armas
name: Fernández-Ontiveros, J. A.
name: Jiménez-Ibarra, F.
name: Jonker, P. G.
name: Linares, M.
name: Torres, M. A. P.
name: Shaw, A. W.
name: Rodríguez-Gil, P.
name: van Grunsven, T.
name: Blay, P.
name: Caballero-García, M. D.
name: Castro-Tirado, A.
name: Chinchilla, P.
name: Farina, C.
name: Ferragamo, A.
name: Lopez-Martinez, F.
name: Rubiño-Martin, J. A.
name: Suárez-Andrés, L.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The black hole transient V404 Cygni exhibited a bright outburst in June 2015 that was intensively followed over a wide range of wavelengths. Our team obtained high time resolution optical spectroscopy (~90 s), which included a detailed coverage of the most active phase of the event. We present a database consisting of 651 optical spectra obtained during this event, that we combine with 58 spectra gathered during the fainter December 2015 sequel outburst, as well as with 57 spectra from the 1989 event. We previously reported the discovery of wind-related features (P-Cygni and broad-wing line profiles) during both 2015 outbursts. Here, we build diagnostic diagrams that enable us to study the evolution of typical emission line parameters, such as line fluxes and equivalent widths, and develop a technique to systematically detect outflow signatures. We find that these are present throughout the outburst, even at very low optical fluxes, and that both types of outflow features are observed simultaneously in some spectra, confirming the idea of a common origin. We also show that the nebular phases depict loop patterns in many diagnostic diagrams, while P-Cygni profiles are highly variable on time-scales of minutes. The comparison between the three outbursts reveals that the spectra obtained during June and December 2015 share many similarities, while those from 1989 exhibit narrower emission lines and lower wind terminal velocities. The diagnostic diagrams presented in this work have been produced using standard measurement techniques and thus may be applied to other active low-mass X-ray binaries.
description: Accepted for publication in MNRAS. 23 pages paper, plus a 9 pages appendix with extra tables and figures. 18 figures are included in the paper and 8 in the appendix
Προοπτικές τουριστικής ανάπτυξης περιφερειακής ενότητας Εύβοιας
Creators: name: Παλαιολόγος, Ηλίας
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2021
Subjects: subject: Τουρισμός
subject: Εναλλακτικός τουρισμός
subject: Τουριστική ανάπτυξη

description: Ο κύριος σκοπός της έρευνας σε αυτή την εργασία είναι να διερευνήσει τις προοπτικές ανάπτυξης του τουρισμού στην περιφερειακή ενότητα της Εύβοιας. Ο τουρισμός ενισχύει τα έσοδα της οικονομίας, δημιουργεί χιλιάδες θέσεις εργασίας, αναπτύσσει τις υποδομές μιας χώρας και καλλιεργεί μια αίσθηση πολιτιστικής ανταλλαγής μεταξύ τουριστών-επισκεπτών και πολιτών. Η περιφερειακή ενότητα της Εύβοιας αποτελεί ένα δημοφιλή τουριστικό προορισμό, προσελκύοντας τόσο Έλληνες όσο και των αλλοδαπούς επισκέπτες. Επιπλέον, αποτελεί ένα σημαντικό προορισμό για εναλλακτικό τουρισμό, καθώς συγκεντρώνει πλήθος φυσικών τοπίων, παραδοσιακούς οικισμούς, σπάνια οικοσυστήματα, ενώ διαθέτει μεγάλο αριθμό προσκυνημάτων τοπίων και θρησκευτικών δρώμενων, τα οποία την καθιστούν σημαντικό προορισμό θρησκευτικού περιεχομένου. Προς την ενίσχυση του τουρισμού θα αναφερθούν μια σειρά από προτάσεις και δράσεις. Για να διερευνηθούν οι δυνατότητες και οι προοπτικές ανάπτυξης του τουρισμού στην Εύβοια, διεξήχθη μια έρευνα σχετικά με την υπάρχουσα κατάσταση και την καταγραφή των προβλημάτων που εμποδίζουν την ανάπτυξή του.
New constraints on R-parity violation from proton stability
Creators: name: Bhattacharyya, Gautam
name: Pal, Palash B.
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We derive stringent upper bounds on all the $(λ''_{ijk} μ_l)$-type combinations from the consideration of proton stability, where $λ''_{ijk}$ are baryon-number-violating trilinear couplings and $μ_l$ are lepton-number-violating bilinear mass parameters in a R-parity-violating supersymmetric theory.
description: 4 pages, Latex, uses axodraw.sty (in the revised version all combinations of the form $\lambda"_{ijk}\mu_l$ have been constrained, using one-loop graphs) To appear in Phys. Lett. B
Rhaponticum scariosum subsp. rhaponticum Greuter
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Rhaponticum
Rhaponticum scariosum
Rhaponticum scariosum lam. subsp. rhaponticum (l.) greuter

description: Centaurea rhapontica Linnaeus, Species Plantarum 2: 915. 1753.
"Habitat in Alpibus Helveticis, Veronae." RCN: 6610.
 Lectotype (Dittrich in Candollea 39: 49. 1984): Herb. Clifford: 421, Centaurea 9 (BM-000647261).
 Current name:  Rhaponticum scariosum  Lam. subsp.  rhaponticum  (L.) Greuter (Asteraceae).
 Note: Greuter (in Greuter & Raab-Straube in Willdenowia 35: 237-238. 2005) discusses both the name and the form of the specific epithet.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part C), pp. 370-473 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 402, DOI: 10.5281/zenodo.291971
The influencing factors and changes of cognitive function within 40 Rasmussen encephalitis patients that received a hemispherectomy
Creators: name: Liu, Dong
name: Yuguang, Guan
name: Zhou, Jian
name: Zhai, Feng
name: Chen, Lingling
name: Li, Tianfu
name: Wang, Mengyang
name: Luan, Guoming
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Mental Health

description: To evaluate the influencing factors and cognitive functional changes in Rasmussen encephalitis (RE) patients who received a hemispherectomy. Forty RE patients underwent a hemispherectomy with at least a 2 years follow- up were included in this study . Postoperative seizure outcomes were evaluated according to the Engle classification scale. Univariate analysis and a multivariate logistic regression model in a backward fashion were used to identify the potential predictors of cognitive function. All 40 patients had an Engle classification outcome at a 2 years follow-up. Univariate and multivariate analyses revealed that seizure duration (OR 10.06, 95% CI 1.54–3.85, p = 0.038), age at surgery (OR 3.06, 95% CI 1.21–3.56, p = 0.043), and MRI score (OR 0.09, 95% CI 0.01–0.67 p = 0.024) are associated with postoperative cognitive outcomes respectively. Moreover,  VIQ and PIQ were negatively correlated linearly with duration of seizures and MRI score. Patients with a good VIQ and PIQ before the operation were more likely to have a better VIQ and PIQ postoperatively (p < 0.001 and p < 0.001, respectively). And, operation side is an important factor affecting cognitive function; therefore, a left hemispherectomy has a greater impact on the patient’s IQ and language. RE patients’ cognitive dysfunctions are improved after a hemispherectomy. Right-side operation can achieve better postoperative cognitive outcomes especially in VIQ and language. A shorter duration of seizures, early age at surgery, and less severe brain atrophy suggest better cognitive outcomes after a hemispherectomy.
Biochemical mechanisms for selectivity governing RNA and DNA replication
Creators: name: Dangerfield, Tyler Lane
name: 0000-0003-1413-2082
Publisher: name: The University of Texas at Austin
Year: 2021
Subjects: DNA polymerase
Kinetics
Fluorescence
Stopped flow
Quench flow
SARS-CoV-2
COVID-19
Bacteriophage T7
RNA polymerase
Unnatural amino acid

description: Enzymes that catalyze DNA and RNA replication are biologically important and provide examples to understand enzyme specificity as the correct substrate and alternate substrates are well known. The DNA polymerase from bacteriophage T7 has been a model system for understanding high-fidelity DNA replication, yet outstanding questions remain about the controversial nucleotide induced conformational change. I developed methods to directly measure the conformational change by site specifically incorporating a fluorescent unnatural amino acid into the enzyme at a position that gives a fluorescence signal upon nucleotide binding. In addition, I developed high throughput methods to analyze kinetic samples by capillary electrophoresis to assist in the kinetic analysis of DNA replication. Kinetic studies show that the conformational change is the primary determinant of specificity at the polymerase active site. I also characterized the enzyme’s 3’--5’ proofreading exonuclease activity and showed that the enzyme has multiple opportunities to correct mistakes during replication. I also used molecular dynamics simulation methods to propose a structure of the proofreading exonuclease editing complex. While finishing studies on the T7 DNA polymerase, the SARS-CoV-2 pandemic devastated the world. I used techniques developed in my previous studies to characterize the RNA dependent RNA polymerase (RdRp) from SARS-CoV-2, a prime target for antiviral drugs to stop replication of the virus. I developed methods to express the tag free complex in E. coli and subsequent purification to give highly active enzyme, which for the first time met standards for physiologically relevant activity. I characterized the pre-steady state kinetics of UTP and ATP incorporation and found that the enzyme catalyzes nucleotide incorporation at a fast rate, sufficient to replicate the 30 kb viral genome in less than 2 minutes. The ATP analog Remdesivir triphosphate, the only FDA approved treatment for COVID-19, was then studied to calculate the discrimination relative to ATP. We found that Remdesivir is incorporated more efficiently than ATP and acts as a delayed chain terminator, although this termination can be partially overcome by incubation with high nucleotide concentrations. Cryo-EM was used to determine the structure of the Remdesivir stalled RdRp complex and we found that the translocation step was inhibited after incorporation of 3 Remdesivirs due to a steric block between Remdesivir and the enzyme.