cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MECHANICAL PROPERTY CHARACTERIZATION OF FALSE BANANA/GLASS FIBER REINFORCED HYBRID COMPOSITE MATERIALS FOR WIND TURBINE BLADES UNDER FATIGUE LOAD
Creators: name: TEMESGEN BATU GEMECHU
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2019
Subjects: False Banana, Glass Fiber, Wind turbine blade, composite, fatigue

description: This thesis is open access After January 2021
The proteinopathy of D169G and K263E mutants at the RNA Recognition Motif (RRM) domain of tar DNA-binding protein (tdp43) causing neurological disorders: A computational study
Creators: name: Vishwambhar Vishnu Bhandare
name: Amutha Ramaswamy
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 60506 Virology

description: One of the multitasking proteins, transactive response DNA-binding protein 43 (tdp43) plays a key role in RNA regulation and the two pathogenic mutations such as D169G and K263E, located at the RNA Recognition Motif (RRM) of tdp43, are reported to cause neurological disorders such as Amyotrophic Lateral Sclerosis and FrontoTemporal Lobar Degeneration. As the exploration of the proteinopathy demands both structural and functional characterizations of mutants, a comparative analysis on the wild type and mutant tdp43 (D169G and K263E) and their complexes with RNA has been performed using computational approaches. Molecular dynamics simulations revealed comparatively stable mutant structures compared to wild type tdp43. Both mutants show lesser binding affinity toward RNA molecule when compared to the wild type tdp43. Some of the observed features, including the increased solvent-accessible surface area, conformational flexibility as well as unfolding of tdp43, and the altered RNA conformation in tp43-RNA complex, reveal the susceptibility of these mutants to induce conformational changes in tdp43 for a possible aggregation in the cytoplasm. Particularly, the enhanced aggregation propensity of both mutants also evidences the higher probability of cytoplasmic aggregation of tdp43 mutants. Hence, the present analysis highlighting the structural and functional aspects of wild and mutant tdp43 will form the basis to gain insight into the proteinopathy of tdp43 and the related structure-based drug discovery. Thus, tdp43 can be used as target to develop novel therapeutic approaches or drug designing.
Proto Ethical Guidelines for Mathematics Practice Deck of Cards
Creators: name: Tractenberg, Rochelle E.
name: Walk, Stephen
Publisher: name: OSF
Year: 2021
Subjects: subject: Mathematics
subject: FOS: Mathematics
subject: applied ethics
subject: case studies
subject: professional ethics
subject: professional identity
subject: stewardship
subject: teaching ethics

description: Each Proto Guideline Element is on its own card for use in educational gaming
Is Solar Minimum 24/25 Another Unusual One?
Creators: name: Li, Huichao
name: Feng, Xueshang
name: Wei, Fengsi
Publisher: name: arXiv
Year: 2021
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The solar minimum 23/24 is considered to be unusual because it exhibits features that differ notably from those commonly seen in pervious minima. In this letter, we analyze the solar polar magnetic field, the potential-field solution of the solar corona, and the in-situ solar wind measurements to see whether the recent solar minimum 24/25 is another unusual one. While the dipolar configuration that are commonly seen during minimum 22/23 and earlier minima persist for about half a year after the absolute minimum of solar cycle 24, the corona has a morphology more complex than a simple dipole before the absolute minimum. The fast solar wind streams are less dominant than minimum 23/24. The IMF strength, density and mass flux that are historically low in the minimum 23/24 are regained during minimum 24/25, but still do not reach the minimum 22/23 level. From the analysis of this Letter, it seems that the minimum 24/25 is only partially unusual, and the recovery of the commonly minimum features may result from the enhancement of the polar field.
description: Accepted by APJL
An independent event of Neolithic cattle domestication on the South-eastern Balkans: evidence from prehistoric aurochs and cattle populations
Creators: name: Hristov, Peter
name: Spassov, Nikolai
name: Iliev, Nikolai
name: Radoslavov, Georgi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Neolithic/Chalcolithic livestock domestication is an important issue for understanding the mode of life and economics of ancient human communities. The Balkans appears to be a crucial point for clarifying the socio-economical interrelations between the Oldest Middle Eastern/Anatolian and newly formed cultures in Europe. Two main hypotheses regarding the early history of cattle domestication, from their ancestor – the aurochs, have been discussed: multipoint domestication centers or single point origin and subsequent worldwide dissemination. In this study, we provide molecular data about the Balkan aurochs for the first time as well as additional information for the Neolithic/Chalcolithic cattle populations in this geographic location. A total of seventeen samples from different ancient settlements were analyzed according to D-loop control region. The results did not show different genetic profile of wild and domestic populations. All haplotypes were found to belong to the basic macro-haplogroup T. The majority of specimens (n = 14) were defined to form a new Balkan-specific T6 haplogroup. Only two of the ancient samples analyzed were assigned to the T3 haplotype predominating in Europe. We attempt to throw new light on the earliest cattle domestication events in Europe, thus, the results presented are discussed in two directions: (a) The possibility of local independent domestication processes in Neolithic South-Eastern Europe; (b) The single point domestication in the Middle East and subsequent cattle dissemination in Europe. Our data does not exclude the possibility for independent domestication events followed by a second wave of parallel dissemination of cattle herds via the Mediterranean route.
Facile preparation of thermosensitive and water-soluble fluorescent polymer containing curcumin and its cell imaging
Creators: name: Yang, Qingmin
name: Liu, Hongmei
name: Cheng, Jiarun
name: Hu, Chaoying
name: Zhang, Shuchen
name: Li, Xiaomeng
name: Zhao, Hongchi
name: Bai, Libin
name: Wang, Sujuan
name: Wu, Yonggang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biophysics
Biochemistry
Space Science
Physical Sciences not elsewhere classified
Medicine
Cell Biology
Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: A novel thermosensitive and water-soluble fluorescent polymer PNIPAM-curcumin (P2) containing curcumin unit was synthesized through one-pot method. The chemical structure and optical properties of compounds and polymer were characterized and tested. As the results turned out that P2 displayed excellent water solubility, thermosensitivity and exhibited strong fluorescence emission band in water. Moreover, P2 was further investigated by MTT assay and live cell imaging with HeLa cells. P2 did not have cytotoxicity in concentration of 200 µg · mL−1 within 48 h and the intracellular fluorescence intensity enhanced with the concentration of P2 varying from 0 to 500 µg · mL−1. According to the experimental results, as a fluorescence probe, P2 synthesized does not only possess nice water solubility but also has the advantage of no cytotoxicity, and it can easily enter the cells, which indicates that it is a characteristic of high sensitivity and responsiveness. Therefore, P2 will have immense potential to be applied in biomedical fields.
Facile Preparation of Thermosensitive and Water-Soluble Fluorescent Polymer Containing Curcumin and its Cell Imaging
Creators: name: Yang, Qingmin
name: Liu, Hongmei
name: Cheng, Jiarun
name: Hu, Chaoying
name: Zhang, Shuchen
name: Li, Xiaomeng
name: Zhao, Hongchi
name: Bai, Libin
name: Wang, Sujuan
name: Wu, Yonggang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biophysics
Biochemistry
Space Science
Physical Sciences not elsewhere classified
Medicine
Cell Biology
Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: A novel thermosensitive and water-soluble fluorescent polymer PNIPAM-Curcumin (P2) containing curcumin unit was synthesized via one-pot method. The chemical structure and optical properties of compounds and polymer were characterized and tested. As the results turned out that P2 displayed excellent water solubility, thermosensitivity and exhibited strong fluorescence emission band in water. Moreover, P2 was further investigated by MTT assay and lives cell imaging with HeLa cells. P2 did not have cytotoxicity in concentration of 200 µg · mL−1 within 48 h and the intracellular fluorescence intensity enhanced with the concentration of P2 varying from 0 to 500 µg · mL−1. According to the experimental results, as a fluorescence probe, P2 synthesized by us not only possesses nice water solubility but also has the advantage of no cytotoxicity, and it can easily enter the cells, which indicates it's a characteristic of high sensitivity and responsiveness. Therefore, P2 will have immense potential to be applied in biomedical fields.
Enthalpy-driven interaction between dihydropyrimidine compound and bovine serum albumin: a spectroscopic and computational approach
Creators: name: Kongot, Manasa
name: Maurya, Neha
name: Dohare, Neeraj
name: Parray, Mehraj ud din
name: Maurya, Jitendra Kumar
name: Kumar, Amit
name: Patel, Rajan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Virology

description: Enthalpy-driven interaction between dihydropyrimidine compound and bovine serum albumin: a spectroscopic and computational approach
Enthalpy-driven interaction between dihydropyrimidine compound and bovine serum albumin: A spectroscopic and computational approach
Creators: name: Kongot, Manasa
name: Maurya, Neha
name: Dohare, Neeraj
name: Parray, Mehraj ud din
name: Maurya, Jitendra Kumar
name: Kumar, Amit
name: Patel, Rajan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Virology

description: Enthalpy-driven interaction between dihydropyrimidine compound and bovine serum albumin: A spectroscopic and computational approach
Polyol monoterpenes isolated from Chenopodium ambrosioides
Creators: name: Hou, Shu-Qun
name: Li, Yan-Hong
name: Huang, Xiang-Zhong
name: Li, Rong
name: Lu, Huai
name: Tian, Kai
name: Ruan, Rong-Sheng
name: Li, Yu-Kui
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: Phytochemical study on the 95% ethyl alcohol extract of stems of Chenopodium ambrosioides resulted in the isolation of two new polyol monoterpenes, 4-hydroxy-4(α or β)-isopropyl-2-methyl-2-cyclohexen-1-one (1) and 1-methyl-4β- isopropyl-1-cyclohexene-4α,5α,6α-triol (2), together with five known compounds, (1S,2S,3R,4S)-1-methyl-4-(propan-2-yl)cyclohexane-1,2,3,4-tetrol (3), (1R,2S,3S,4S)- 1,2,3,4-tetrahydroxy-p-menthane (4), (1R,2S)-3-p-menthen-1,2-diol (5), (1R,4S)-p- menth-2-en-1-ol (6) and 1,4-dihydroxy-p-menth-2-ene (7). The structures of the new compounds were established on the basis of detailed spectroscopic evidence including extensive 1D and 2D NMR techniques. Compounds 1–7 were evaluated for their anti-inflammatory activity, and compound 1 showed moderate ability to inhibit NO production of LPS-stimulated RAW 264.7 macrophages with an IC50 value of 16.83 μM.
Direct determination of hydrazine, methylhydrazine, and 1,1-dimethylhydrazine by zwitterionic hydrophilic interaction liquid chromatography with amperometric detection
Creators: name: Kosyakov, Dmitry S.
name: Pikovskoi, Ilya I.
name: Ul’yanovskii, Nikolay V.
name: Kozhevnikov, Alexander Yu.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: A promising alternative to ion-chromatographic methods currently used for the direct determination of hydrazines is provided by hydrophilic interaction liquid chromatography (HILIC). In this work, we propose a method for the simultaneous determination of hydrazine, methylhydrazine and 1,1-dimethylhydrazine in natural waters and soils based on a combination of chromatographic separation on a zwitterionic sulfobetaine stationary phase (Nucleodur HILIC) in the HILIC mode with amperometric detection. Effects of different factors on the retention of analytes were studied and the optimum conditions of analysis were found. We recommend a mixture of acetonitrile with an aqueous phosphate buffer solution of pH 2.5 (78:22 v/v) with an ionic strength of 20 mM as a mobile phase. Detection in the direct current mode was performed at a working electrode potential of 1.1 V. The advantages of the method are the high efficiency of separation, rapidity, high sensitivity and a wide dynamic range of analyte concentrations, covering four orders of magnitude. The attained LOD values for analytes lie in the range 0.07–0.13 μg L–1, which is two orders of magnitude lower than those in currently used methods of ion chromatography with electrochemical and mass spectrometric detection. The method was validated on samples of natural waters of different origin using the added–found technique. It was found that the error of analysis did not exceed 10% for river and ground waters and increased to 20–30% for peat bog surface waters. The possibility of application of the developed method to the analysis of soils was shown on samples of peat bog soils selected at places of impact of the first steps of carrier rockets and polluted by rocket fuel based on 1,1-dimethylhydrazine.
Abietane diterpenoids from Cephalotaxus lanceolata
Creators: name: Chen, Xiao-Jiao
name: Ni, Ling
name: Bao, Mei-Fen
name: Wang, Li
name: Cai, Xiang-Hai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: A new abietane diterpenoid, 12-O-methyl-20-deoxocarnosol-3-one (1), and eight known abietane diterpenoids including 13-abietadien-12-one (2), 5,6-dehydrosugiol (3), sugiol (4), torreyayunnin (5), taxusabietane A (6), hinokiol (7), 3-acetoxyabieta-8,11,13-trien-12-ol (8), and martiusane (9) were obtained from leaves and twigs of Cephalotaxus lanceolata. The structures of isolated compounds (1–9) were determined based on analysis of their spectroscopic data and comparison with those reported in the literature. Compounds 3, 8 and 9 were first isolated from the plants of Cephalotaxus genus.
Efficient degradation of organic phosphorus in glyphosate wastewater by catalytic wet oxidation using modified activated carbon as a catalyst
Creators: name: Xing, Bo
name: Chen, Honglin
name: Zhang, Xiaoming
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Glyphosate (PMG) wastewater, which is an organic phosphorus (OP) wastewater containing 200–3000 mg/L PMG, was treated via catalytic wet oxidation (CWO) to degrade PMG to orthophosphate (). The catalysts were activated carbons (ACs) modified by H2O2 oxidation and thermal treatment with ammonia or melamine. The catalysts were characterized using N2 adsorption/desorption, Boehm titration, and X-ray photoelectron spectroscopy. The CWO experiments were performed in a co-current upflow fixed-bed reactor at 110–130°C and under 1.0 MPa. The AC modified by H2O2 and melamine had the highest catalytic activity and had excellent stability in the continuous 55-day test: 100% PMG removal and over 93% OP removal for different samples of real PMG wastewater. More pyrrolic nitrogen, pyridinic nitrogen, and graphitic nitrogen along with quinone oxygen functional groups on the surface of the AC showed higher catalytic activity according to linear fitting results. The identiﬁcation and quantiﬁcation of critical reaction intermediaries and the main end products of PMG degradation were possible, and a degradation pathway was proposed.
Supplemental table 1 from Wsv023 interacted with Litopenaeus vannamei γ-tubulin complex associated proteins 2, and decreased the formation of microtubules
Creators: name: Chen, Yihong
name: Bi, Haitao
name: Li, Xiaoyun
name: Zhang, Zezhi
name: Yue, Hatao
name: Weng, Shaoping
name: He, Jianguo
Publisher: name: The Royal Society
Year: 2017

description: WSSV copy number in muscle of shrimp injected with PBS, dseGFP or dswsv023, plus WSSV infection
Supplemental figure 3 from Wsv023 interacted with Litopenaeus vannamei γ-tubulin complex associated proteins 2, and decreased the formation of microtubules
Creators: name: Chen, Yihong
name: Bi, Haitao
name: Li, Xiaoyun
name: Zhang, Zezhi
name: Yue, Hatao
name: Weng, Shaoping
name: He, Jianguo
Publisher: name: The Royal Society
Year: 2017

description: Similarity analysis of wsv023
Supplemental figure 2 from Wsv023 interacted with Litopenaeus vannamei γ-tubulin complex associated proteins 2, and decreased the formation of microtubules
Creators: name: Chen, Yihong
name: Bi, Haitao
name: Li, Xiaoyun
name: Zhang, Zezhi
name: Yue, Hatao
name: Weng, Shaoping
name: He, Jianguo
Publisher: name: The Royal Society
Year: 2017

description: Schematic representation of the structural domains of LvGCP2 and phylogenetic analysis of the GCP2 proteins
title: Political and Socioeconomic Factors That Determine the Financial Outcome of Successful Green Innovation
Creators: name: Riehl, Kevin
name: Kiesel, Florian
name: Schiereck, Dirk
Publisher: name: MDPI
Year: 2022

description: Green innovation and technology diffusion must be financially and commercially attractive to convince corporate decision makers. This paper focuses on the factors that determine the financial outcome of successful green innovation activities conducted by large, listed companies. We employ a cross-industry dataset including more than 97,954 reports on corporate environmentalism from 286 international listed companies. Our results indicate that economic, political, cultural, firm-specific, investor-related, and governance factors significantly determine the financial performance of green innovation, measured by abnormal returns. Moreover, we can show that factors that reduce the competition in green innovation markets benefit the financial success of firms operating via them. Finally, we find an opposing influence for several factors that benefit earlier stages of innovation (e.g., research output) while harming the later stages (e.g., market introduction and financial performance). These findings imply that a spatial separation strategy for different stages of innovation supports corporate environmentalism activities. Moreover, physical property rights, the governments’ willingness to support green technologies, and economic framework conditions such as oil price, GDP, or public R&D budget need to be balanced by policymakers to address and stimulate green innovation.
Supplemental figure 1 from Wsv023 interacted with Litopenaeus vannamei γ-tubulin complex associated proteins 2, and decreased the formation of microtubules
Creators: name: Chen, Yihong
name: Bi, Haitao
name: Li, Xiaoyun
name: Zhang, Zezhi
name: Yue, Hatao
name: Weng, Shaoping
name: He, Jianguo
Publisher: name: The Royal Society
Year: 2017

description: Multiple sequence alignment of the GCP2 proteins
Supplementary Material for: In-Office Application of Fluoride Gel or Varnish: Cost-Effectiveness and Expected Value of Perfect Information Analysis
Creators: name: Schwendicke, F.
name: Stolpe, M.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Application of fluoride gel/varnish (FG/FV) reduces caries increments but generates costs. Avoiding restorative treatments by preventing caries might compensate for these costs. We assessed the cost-effectiveness of dentists applying FG/FV in office and the expected value of perfect information (EVPI). EVPI analyses estimate the economic value of having perfect knowledge, assisting research resource allocation. A mixed public-private-payer perspective in Germany was adopted. A population of 12-year-olds was followed over their lifetime, with caries increments modelled using wide intervals to reflect the uncertainty of caries risk. Biannual application of FV/FG until age 18 years was compared to no fluoride application. Effectiveness parameters and their uncertainty were derived from systematic reviews. The health outcome was caries increment (decayed, missing, or filled teeth; DMFT). Cost calculations were based on fee catalogs or microcosting, including costs for individual-prophylactic fluoridation and, for FG, an individualized tray, plus material costs. Microsimulations, sensitivity, and EVPI analyses were performed. On average and applied to a largely low-risk population, no application of fluoride was least costly but also least effective (EUR 230; 11 DMFT). FV was more costly and effective (EUR 357; 7 DMFT). FG was less effective than FV and also more costly when using individualized trays. FV was the best choice for payers willing to invest EUR 39 or more per avoided DMFT. This cost-effectiveness will differ in different settings/countries or if FG/FV is applied by other care professionals. The EVPI was mainly driven by the individual's caries risk, as FV/FG were significantly more cost-effective in high-risk populations than in low-risk ones. Future studies should focus on caries risk prediction.
Measured Variables
Creators: name: Rodrigues, Victória Do Monte
name: Abreu, Marcia
Publisher: name: OSF Registries
Year: 2024

description: The experiment will be carried out in the afternoon, avoiding the peak of endogenous cortisol that occurs in the morning. The saliva sample will be collected after two hours without food intake (if any juice is drunk in this interval, 10 minutes interval will be respected before carrying out the collection), ensuring that the child's mouth is clean. The saliva samples will be immediately refrigerated and taken to the hospital bio repository where it will be kept under 176 degrees Fahrenheit. The variation in biomarkers will be analyzed by comparing the baseline level (value obtained in the collection immediately before the session) with the level reached at the end of the procedure, as what matters is not the absolute number but the variation upward or downward (or stability).
The individual quantification of biomarkers found before and after the session will be provided through a confidential electronic report, prepared by a specialized laboratory in scientific analysis, using an ELISA kit. All information regarding ELISA methodology (kit sensitivity, calibration curve ranges, assay procedures, etc.) is presented in the kit protocols provided in the attachments. The results are released in numerical and sequential form (from 1 to the end) in a PDF file (including data from ELISA reader equipment). The analyses will be performed in duplicate; the duplicate averages will be presented in an EXCEL table. The results obtained in the quantification of biomarkers will be investigated through Multiple Correspondence Analysis, which allows the analysis of two or more variables simultaneously. This will make it possible to analyze psychological and physiological relationships (changes in biomarkers and pain scale) with the various elements investigated (linguistic, contextual, and socio-economic-cultural).
Gender approaches to evolutionary multi-objective optimization using pre-selection of criteria
Creators: name: Zdzisław Kowalczuk
name: Białaszewski, Tomasz
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: A novel idea to perform evolutionary computations (ECs) for solving highly dimensional multi-objective optimization (MOO) problems is proposed. Following the general idea of evolution, it is proposed that information about gender is used to distinguish between various groups of objectives and identify the (aggregate) nature of optimality of individuals (solutions). This identification is drawn out of the fitness of individuals and applied during parental crossover in the processes of evolutionary multi-objective optimization (EMOO). The article introduces the principles of the genetic-gender approach (GGA) and virtual gender approach (VGA), which are not just evolutionary techniques, but constitute a completely new rule (philosophy) for use in solving MOO tasks. The proposed approaches are validated against principal representatives of the EMOO algorithms of the state of the art in solving benchmark problems in the light of recognized EC performance criteria. The research shows the superiority of the gender approach in terms of effectiveness, reliability, transparency, intelligibility and MOO problem simplification, resulting in the great usefulness and practicability of GGA and VGA. Moreover, an important feature of GGA and VGA is that they alleviate the ‘curse’ of dimensionality typical of many engineering designs.
A new prenylated flavone from Pleione bulbocodioides
Creators: name: Li, Yuan
name: Wu, Ze-Hong
name: Zeng, Ke-Wu
name: Zhao, Ming-Bo
name: Jiang, Yong
name: Li, Jun
name: Tu, Peng-Fei
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: A new prenylated flavone, 3,5,7,3′-tetrahydroxy-8,4′-dimethoxy-6-(3-methylbut-2- enyl)flavone (1), together with three known flavone derivatives (2–4), two known dihydrophenanthrenes (5–6), two known lignin derivatives (7–8), and three known phenolic glycoside compounds (9–11) were isolated from the n-BuOH extract of Pleione bulbocodioides. High-resolution electrospray ionization mass spectroscopy (HRESIMS), FTIR spectroscopy, and NMR techniques were used to elucidate the structures of these compounds. Biological investigations showed that compound 5, 4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene, exhibited potent anti-inflammatory activity on LPS-stimulated NO production in BV-2 microglial cells, with IC50 value of 5.44 μM.
Direct determination of hydrazine, methylhydrazine, and 1,1-dimethylhydrazine by zwitterionic hydrophilic interaction liquid chromatography with amperometric detection/
Creators: name: Kosyakov, Dmitry S.
name: Pikovskoi, Ilya I.
name: Ul’yanovskii, Nikolay V.
name: Kozhevnikov, Alexander Yu.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: A promising alternative to ion-chromatographic methods currently used for the direct determination of hydrazines is provided by hydrophilic interaction liquid chromatography (HILIC). In this work, we propose a method for the simultaneous determination of hydrazine, methylhydrazine and 1,1-dimethylhydrazine in natural waters and soils based on a combination of chromatographic separation on a zwitterionic sulfobetaine stationary phase (Nucleodur HILIC) in the HILIC mode with amperometric detection. Effects of different factors on the retention of analytes were studied and the optimum conditions of analysis were found. We recommend a mixture of acetonitrile with an aqueous phosphate buffer solution of pH 2.5 (78:22 v/v) with an ionic strength of 20 mM as a mobile phase. Detection in the direct current mode was performed at a working electrode potential of 1.1 V. The advantages of the method are the high efficiency of separation, rapidity, high sensitivity and a wide dynamic range of analyte concentrations, covering four orders of magnitude. The attained LOD values for analytes lie in the range 0.07–0.13 μg L–1, which is two orders of magnitude lower than those in currently used methods of ion chromatography with electrochemical and mass spectrometric detection. The method was validated on samples of natural waters of different origin using the added–found technique. It was found that the error of analysis did not exceed 10% for river and ground waters and increased to 20–30% for peat bog surface waters. The possibility of application of the developed method to the analysis of soils was shown on samples of peat bog soils selected at places of impact of the first steps of carrier rockets and polluted by rocket fuel based on 1,1-dimethylhydrazine.
SEISMIC RESPONSES OF CONCENTRICALLY BRACED STEEL FRAME BUILDINGS
Creators: name: AHMED SEID YIMAM
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Bracing System, seismic response, Pushover analysis, lateral stability, lateral displacement, seismostruct

description: This paper presents seismic response of concentrically braced steel frame buildings. Lateral
 stability is important for the steel structures in the seismic zones. The effective way to
 increase the lateral strength is by means of bracing system. In order to achieve the goal of
 study different configurations of bracing systems are undertaken, Diagonal braced frames
 (DBF), Inverted V- braced frames (IVBF) and crossed (X) braced frames (XBF).
 To study the response of braced frame on the lateral stability of steel building, three models
 are taken two storey, four storey and eight storey steel frame buildings. It shows how to model
 the steel buildings using a finite element computer software called seismostruct 2016 and
 response of frames had been studied using non-linear static analysis (push over analysis).
 Various parameters such as capacity curves, lateral load capacity, inter storey drift, lateral
 displacement, performance criteria, bending moments and reaction forces were studied. The
 result shows that the lateral displacements of the building using X-braced systems are
 decreased by an average ratio of 47.83%. This indicates that this bracing gives better
 performance for lateral load resistance
Can Citizen Science help us to fight against Light Pollution?
Creators: name: Gonzalez, Esteban
Publisher: name: Zenodo
Year: 2020
Subjects: light pollution
citizen science

description: These slides were presented during the 14th European Symposium for Protection of Night Sky celebrated in Mulranny, Ireland. This presentation shows a short list of tools used to generate data in the Light Pollution domain as well as create awareness among the citizens. Some of the pilots integrated in the European project ACTION were presented during the symposium.
title: Préface_Manuel pratique de l'amateur de chiens
Creators: name: AmateurS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: ID_PARA_00576
description: Préface
Nationwide incidence of motor neuron disease using the French health insurance information system database
Creators: name: Kab, Sofiane
name: Moisan, Frédéric
name: Pierre-Marie Preux
name: Marin, Benoît
name: Elbaz, Alexis
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy

description: Objective: There are no estimates of the nationwide incidence of motor neuron disease (MND) in France. We used the French health insurance information system to identify incident MND cases (2012–2014), and compared incidence figures to those from three external sources. Methods: We identified incident MND cases (2012–2014) based on three data sources (riluzole claims, hospitalisation records, long-term chronic disease benefits), and computed MND incidence by age, gender, and geographic region. We used French mortality statistics, Limousin ALS registry data, and previous European studies based on administrative databases to perform external comparisons. Results: We identified 6553 MND incident cases. After standardisation to the United States 2010 population, the age/gender-standardised incidence was 2.72/100,000 person-years (males, 3.37; females, 2.17; male:female ratio = 1.53, 95% CI1.46–1.61). There was no major spatial difference in MND distribution. Our data were in agreement with the French death database (standardised mortality ratio = 1.01, 95% CI = 0.96–1.06) and Limousin ALS registry (standardised incidence ratio = 0.92, 95% CI = 0.72–1.15). Incidence estimates were in the same range as those from previous studies. Conclusions: We report French nationwide incidence estimates of MND. Administrative databases including hospital discharge data and riluzole claims offer an interesting approach to identify large population-based samples of patients with MND for epidemiologic studies and surveillance.
Data collection procedures
Creators: name: Rodrigues, Victória Do Monte
name: Abreu, Marcia
Publisher: name: OSF Registries
Year: 2024

description: The study will involve 60 hospitalized children (boys and girls) aged between 6 and 10 years, with preserved cognitive conditions and without sedation. Deaf, blind or neurodivergent children, in addition to those who do not understand Portuguese, will not be included. Every day, from Monday to Friday, the hospital staff will inform us which are the eligible children, considering those criteria. They will receive no payment. We expect to complete sample collection within 6 months.
Angular dependence of hump-shape Hall Effects for distinguishing between Karplus-Luttinger and Geometrical Origins
Creators: name: Lim, Z. S.
name: Chow, L. E.
name: Khoo, K. H.
name: Omar, G. J.
name: Zhang, Z.
name: Luo, Z.
name: Yan, H.
name: Yang, P.
name: Laskowski, R.
name: Ariando, A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Among the vast magnetic heterostructures explored in Condensed Matter Physics, two contrasting interpretations of the hump-shaped Hall Effects remain ambiguous and debated, namely, the overlap of two opposite-signed Karplus-Luttinger Hall loops associated with inhomogeneous collinear domains with perpendicular anisotropy, or the Geometrical/Topological Hall Effect emanated from hexagnal close-packed lattice of Skyrmion ground state with smoothly varying non-collinear moments. Their similarity in topology implies difficulty in discrimination via magnetic imaging. Here, this ambiguity is overcome and clarified by the divergence exponent of hump peak fields extracted from Hall measurements with magnetic field rotation on several heterostructures. Their difference in sensitivity to in-plane fields reveals that the former mechanism involves higher uniaxial anisotropy than the latter, departing from the Skyrmion ground state regime by the Ginzburg-Landau framework of triple-q spin-wave superposition. Numerous material systems can be summarized into a single curve of divergence exponent versus the collinear quality factor, bridging the crossover of the two mentioned mechanisms.
description: 25 Pages and 5 figures in the main text, 14 pages and 6 figures in the Supporting Information
SEISMIC PERFORMANCE ASSESSMENT OF REINFORCED CONCRETE BUILDING UNDER BI-AXIAL GROUND MOTION
Creators: name: EYERUSALEM ABERA ASSEFA
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Seismic performance Assessment, Nonlinear Static Analysis, Bi-Axial Ground motion Plan Irregular and Plan Regular RC building .

description: Seismic performance assessment of two buildings eight story plan regular and five story plan
 Irregular (L-shaped in the plan) buildings are carried out using a finite element software package
 implementing fiber-based beam-column element approach taking into account the geometric and
 materials nonlinearities for uni-axial loading and bi-axial loading. Assessment of performance is
 done by evaluating capacity curve (pushover curve), base shear, interstory drift ratio and story
 displacement. The study as a whole makes an effort to evaluate the effect of biaxial loading on RC
 building the objective of the work is to carry out Pushover analysis for case study RC buildings
 frames. The results obtained were compared with those obtained from the uniaxial excitation for the
 two considered buildings. The analytical results show that there is a reduction in base shear capacity
 by 6% and 8% when loaded biaxially compared to X-direction uniaxial loading and Y-direction
 uni-Axial loading respectively for eight story plan regular RC frame building and a reduction of
 based shear capacity of 16% for X- direction uni-axial loading and 12.7% for Y- direction uni-axial
 loading for five story L shaped plan building. The results illustrated that significant effect of bi-axial
 loading was observed on base shear of L-Shaped (Plan irregular) building.
Supplementary Material for: New Concept of X-Ray Repair Cross-Complementing Groups 1 Polymorphisms and Gynecologic Cancer Risk
Creators: name: Du, Y.
name: Wang, H.
name: Lv, B.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background: Several meta-analyses have been conducted to examine the possible link between X-ray repair cross-complementing groups 1 (XRCC1) Arg399Gln polymorphism and cervical cancer risk. However, the results are controversial. Therefore, we carried out a more comprehensive meta-analysis to examine whether XRCC1 polymorphisms are associated with general gynecologic cancer risk. Methods: Twenty studies, comprising 4,230 cases and 5,458 controls that included analyses of XRCC1 polymorphisms (Arg194Trp, Arg280His, or Arg399Gln) were included in our study. Results: Overall, no significant association between any of the studied XRCC1 polymorphisms and gynecologic cancer risk was observed. However, in further stratified analyses, the Arg399Gln was definitely associated with increased gynecologic cancer risk in Asians (A vs. G: OR 1.24; 95% CI 1.02-1.53), which was also associated with increased cervical cancer risk (A vs. G: OR 1.20; 95% CI 1.00-1.44). Similarly, the Arg194Trp was significantly associated with increased gynecologic cancer risk in Asians (TT vs. CC: OR 1.87; 95% CI 1.02-3.42) and endometrial cancer (T vs. C: OR 1.45; 95% CI 1.05-2.02). Conclusions: These findings provided evidence that XRCC1 Arg399Gln and Arg194Trp variants may modify the susceptibility to gynecologic cancers based on ethnicity and type. Further studies with large sample size are warranted to extend our findings.
Suzuki–Miyaura coupling of quinazolines containing an unprotected NH2 group: Synthesis and biological testing of quinazoline derivatives
Creators: name: Pulipati, Yadagiri
name: Gurram, Venkateshwarlu
name: Laxmi, S. Vijaya
name: Satyanarayana, Yennam
name: Singh, Karan
name: Kumar, Vinod
name: Sharma, Somesh
name: Pottabathini, Narender
name: Bhaskara Reddy Iska, Vijaya
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: A robust approach to 4-amino quinazoline bi-aryl compounds was developed through Suzuki–Miyaura coupling reaction of quinazoline containing an unprotected NH2 group and arylboronic acids. Pd(dcpf)Cl2 was found to be an efficient catalyst for the reaction. All the compounds were evaluated for antimicrobial activity against gram-positive and gram-negative bacteria and fungi. One of the compounds, 3l, found to be more active against Candida albicans than the standard Miconazole.
Figure S1-S3 and Tables S1 from Aggressive behaviours, food deprivation and the foraging gene
Creators: name: Silu Wang
name: Sokolowski, Marla B.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 60801 Animal Behaviour

description: The supplementary information contains Figure S1-S3, which respectively demonstrates the effect of strain and food-deprivation treatment on offensive behaviours (Figure S1), mean body weight and activity score (Figure S2), as well as escalation rate during aggressive interactions (Figure S3). This file also includes Table S1 in which the details of the principal component analysis (PCA) of offensive and defensive behaviors were shown.
Suzuki-Miyaura Coupling of Quinazolines Containing an Unprotected NH2 Group: Synthesis and Biological Testing of Quinazoline Derivatives
Creators: name: Pulipati, Yadagiri
name: Gurram, Venkateshwarlu
name: Laxmi, S. Vijaya
name: Satyanarayana, Yennam
name: Singh, Karan
name: Kumar, Vinod
name: Sharma, Somesh
name: Pottabathini, Narender
name: Bhaskara Reddy Iska, Vijaya
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: A robust approach to 4-amino quinazoline bi-aryl compounds was developed via Suzuki–Miyaura coupling reaction of quinazoline containing an unprotected NH2 group and arylboronic acids. Pd(dcpf)Cl2 was found to be an efficient catalyst for the reaction. All the compounds were evaluated for antimicrobial activity against Gram-positive and Gram-negative bacteria and fungi. One of the compounds, 3 l, found to be more active against C.albicans than the standard Miconazole.
Availability and need of home adaptations for personal mobility among individuals with spinal cord injury
Creators: name: Hertig-Godeschalk, Anneke
name: Gemperli, Armin
name: Arnet, Ursina
name: Hinrichs, Timo
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Objective: To identify the availability and unmet need of home adaptations (HAs) among the Swiss population with spinal cord injury (SCI). Design: Cross-sectional study. Setting: Swiss Spinal Cord Injury Community Survey 2012. Participants: Individuals aged 16 or older with chronic SCI living in Switzerland. Interventions: Not applicable. Outcome measures: The availability of ten HAs (self-report) was analyzed by sex, age, living situation, indoor mobility, SCI severity, SCI etiology and time since SCI. The unmet need (self-report of not having a HA but needing it) of HAs was analyzed by financial hardship. Results: Among the 482 study participants (mean age 55.2 years, standard deviation 15.0 years, 71.6% males), 85.1% had at least one HA. The most frequent HA was a wheelchair accessible shower (62.7%). Availability of HAs markedly varied with indoor mobility (e.g. 38.4% of participants using a wheelchair had a stair lift compared to 17.4% of those walking) and with SCI severity (e.g. 54.8% of those with complete paraplegia had a wheelchair accessible kitchen worktop compared to 26.0% of those with incomplete paraplegia). Unmet need was highest for adjustable kitchen worktops (78.7% of those with a need) and adjustable kitchen cabinets (75.7%) and lowest for wheelchair accessible showers (9.4%) and grab bars next to the toilet (8.5%). No significant differences in unmet need were found when stratifying for financial hardship. Conclusion: Availability of HAs is dependent on indoor mobility and SCI severity. There is a considerable degree of unmet need for selected HAs, which couldn't be explained by financial hardship.