cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Stabilization of linear time varying system over uncertain channels
Creators: name: Diwadkar, Amit
name: Vaidya, Umesh
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: In this paper, we study the problem of control of discrete-time linear time varying systems over uncertain channels. The uncertainty in the channels is modeled as a stochastic random variable. We use exponential mean square stability of the closed-loop system as a stability criterion. We show that fundamental limitations arise for the mean square exponential stabilization for the closed-loop system expressed in terms of statistics of channel uncertainty and the positive Lyapunov exponent of the open-loop uncontrolled system. Our results generalize the existing results known in the case of linear time invariant systems, where Lyapunov exponents are shown to emerge as the generalization of eigenvalues from linear time invariant systems to linear time varying systems. Simulation results are presented to verify the main results of this paper.
Canadian Gallup Poll # 370
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal and provincial election vote intent(2); past federal and provincial elections vote(2); economic status: city dweller vs. farmer(1); donating body organs(2); personal savings(1); immigration to Canada(1); salaries of government officials(3); predictions for 1975(10). Note: Demographics(14).
Patterned Rydberg excitation and ionisation with a spatial light modulator
Creators: name: van Bijnen, R. M. W.
name: Ravensbergen, C.
name: Bakker, D. J.
name: Dijk, G. J.
name: Kokkelmans, S. J. J. M. F.
name: Vredenbregt, E. J. D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We demonstrate the ability to excite atoms at well-defined, programmable locations in a magneto-optical trap, either to the continuum (ionisation), or to a Rydberg state. To this end, excitation laser light is shaped into arbitrary intensity patterns with a spatial light modulator. These optical patterns are sensitive to aberrations of the phase of the light field, occuring while traversing the optical beamline. These aberrations are characterised and corrected without observing the actual light field in the vacuum chamber.
description: 5 pages, 5 figures
Canadian Gallup Poll # 338
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); predictions for 1970(10); predictions for the next decade(3); predictions for 1990s(12); heart transplants(2); labor unions(1). Note: Demographics(12).
A Global Analysis of the Effectiveness of Marine Protected Areas in Preventing Coral Loss
Creators: name: Bruno, John F.
name: Selig, Elizabeth R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: A variety of human activities have led to the recent global decline of reef-building corals [1], [2]. The ecological, social, and economic value of coral reefs has made them an international conservation priority [2], [3]. The success of Marine Protected Areas (MPAs) in restoring fish populations [4] has led to optimism that they could also benefit corals by indirectly reducing threats like overfishing, which cause coral degradation and mortality [2], [5]. However, the general efficacy of MPAs in increasing coral reef resilience has never been tested.
Spectroscopy of Red Giants in the globular cluster Terzan 8: kinematics and evidence for the surrounding Sagittarius stream
Creators: name: Sollima, A.
name: Carretta, E.
name: D'Orazi, V.
name: Gratton, R. G.
name: Bragaglia, A.
name: Lucatello, S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the results of a spectroscopic survey of Red Giants in the globular cluster Terzan 8 with the aim of studying its kinematics. We derived accurate radial velocities for 82 stars located in the innermost 7 arcmin from the cluster center identifying 48 bona fide cluster members. The kinematics of the cluster have been compared with a set of dynamical models accounting for the effect of mass segregation and a variable fraction of binaries. The derived velocity dispersion appears to be larger than that predicted for mass-segregated stellar systems without binaries, indicating that either the cluster is dynamically young or it contains a large fraction of binaries (>30%). We detected 7 stars with a radial velocity compatible with the cluster systemic velocity but with chemical patterns which stray from those of both the cluster and the Galactic field. These stars are likely members of the Sagittarius stream surrounding this stellar system.
description: 10 pages, 8 figures, accepted for publication by MNRAS
Multi-Channel FFT Architectures Designed via Folding and Interleaving
Creators: name: Unnikrishnan, Nanda K.
name: Parhi, Keshab K.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Signal Processing (eess.SP)
subject: Hardware Architecture (cs.AR)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Computing the FFT of a single channel is well understood in the literature. However, computing the FFT of multiple channels in a systematic manner has not been fully addressed. This paper presents a framework to design a family of multi-channel FFT architectures using {\em folding} and {\em interleaving}. Three distinct multi-channel FFT architectures are presented in this paper. These architectures differ in the input and output preprocessing steps and are based on different folding sets, i.e., different orders of execution.
description: Proc. 2022 IEEE International Symposium on Circuits and Systems (ISCAS)
A Mouse Strain Where Basal Connective Tissue Growth Factor Gene Expression Can Be Switched from Low to High
Creators: name: Sulik, Kathleen K.
name: Maeda, Nobuyo
name: Kim, Hyung-Suk
name: Doherty, Heather E.
name: Hiller, Sylvia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Connective tissue growth factor (CTGF) is a signaling molecule that primarily functions in extracellular matrix maintenance and repair. Increased Ctgf expression is associated with fibrosis in chronic organ injury. Studying the role of CTGF in fibrotic disease in vivo, however, has been hampered by perinatal lethality of the Ctgf null mice as well as the limited scope of previous mouse models of Ctgf overproduction. Here, we devised a new approach and engineered a single mutant mouse strain where the endogenous Ctgf-3′ untranslated region (3′UTR) was replaced with a cassette containing two 3′UTR sequences arranged in tandem. The modified Ctgf allele uses a 3′UTR from the mouse FBJ osteosarcoma oncogene (c-Fos) and produces an unstable mRNA, resulting in 60% of normal Ctgf expression (Lo allele). Upon Cre-expression, excision of the c-Fos-3′UTR creates a transcript utilizing the more stable bovine growth hormone (bGH) 3′UTR, resulting in increased Ctgf expression (Hi allele). Using the Ctgf Lo and Hi mutants, and crosses to a Ctgf knockout or Cre-expressing mice, we have generated a series of strains with a 30-fold range of Ctgf expression. Mice with the lowest Ctgf expression, 30% of normal, appear healthy, while a global nine-fold overexpression of Ctgf causes abnormalities, including developmental delay and craniofacial defects, and embryonic death at E10-12. Overexpression of Ctgf by tamoxifen-inducible Cre in the postnatal life, on the other hand, is compatible with life. The Ctgf Lo-Hi mutant mice should prove useful in further understanding the function of CTGF in fibrotic diseases. Additionally, this method can be used for the production of mouse lines with quantitative variations in other genes, particularly with genes that are broadly expressed, have distinct functions in different tissues, or where altered gene expression is not compatible with normal development.
Canadian Gallup Poll # 340
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); church/synagogue attendance(1); married priests(1); opinion about Prime Minister Trudeau(3); war in Vietnam(1); political parties and issues(4); secessionist tendencies in Canadian provinces(2); inflation(2); teachers' salaries(3); government and opposition job performances(2). Note: Demographics(11).
Canadian Gallup Poll # 291
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Upcoming federal election: vote intent, main issue(2); past federal elections vote(1); Berlin Wall crisis(4); US-Soviet nuclear arms race(1); UN and Cold War(2); labor unions(4); nuclear weapons for Canadian armed forces(3); socialism and free enterprise(3); Canada's dependence on US for defense(2); reading habits(2); New Political Party(3). Note: Demographics(11).
Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation
Creators: name: Rivera, Charlene
name: Sebti, Said M.
name: Muraoka-Cook, Rebecca S.
name: Engelman, Robert W.
name: Earp, H. Shelton
name: Fang, Bin
name: Mahajan, Kiran
name: Mahajan, Nupam P.
name: Schönbrunn, Ernst
name: Chen, Y. Ann
name: Zhu, Weiwei
name: Challa, Sridevi
name: Koomen, John
name: Coppola, Domenico
name: Lopez, Alexis S.
name: Cheng, Jin Q.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The AKT/PKB kinase is a key signaling component of one of the most frequently activated pathways in cancer and is a major target of cancer drug development. Most studies have focused on its activation by Receptor Tyrosine Kinase (RTK) mediated Phosphatidylinositol-3-OH kinase (PI3K) activation or loss of Phosphatase and Tensin homolog (PTEN). We have uncovered that growth factors binding to RTKs lead to activation of a non-receptor tyrosine kinase, Ack1 (also known as ACK or TNK2), which directly phosphorylates AKT at an evolutionarily conserved tyrosine 176 in the kinase domain. Tyr176-phosphorylated AKT localizes to the plasma membrane and promotes Thr308/Ser473-phosphorylation leading to AKT activation. Mice expressing activated Ack1 specifically in the prostate exhibit AKT Tyr176-phosphorylation and develop murine prostatic intraepithelial neoplasia (mPINs). Further, expression levels of Tyr176-phosphorylated-AKT and Tyr284-phosphorylated-Ack1 were positively correlated with the severity of disease progression, and inversely correlated with the survival of breast cancer patients. Thus, RTK/Ack1/AKT pathway provides a novel target for drug discovery.
Efficient Distributed DNNs in the Mobile-edge-cloud Continuum
Creators: name: Malandrino, Francesco
name: Chiasserini, Carla Fabiana
name: Di Giacomo, Giuseppe
Publisher: name: arXiv
Year: 2022
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: In the mobile-edge-cloud continuum, a plethora of heterogeneous data sources and computation-capable nodes are available. Such nodes can cooperate to perform a distributed learning task, aided by a learning controller (often located at the network edge). The controller is required to make decisions concerning (i) data selection, i.e., which data sources to use; (ii) model selection, i.e., which machine learning model to adopt, and (iii) matching between the layers of the model and the available physical nodes. All these decisions influence each other, to a significant extent and often in counter-intuitive ways. In this paper, we formulate a problem addressing all of the above aspects and present a solution concept called RightTrain, aiming at making the aforementioned decisions in a joint manner, minimizing energy consumption subject to learning quality and latency constraints. RightTrain leverages an expanded-graph representation of the system and a delay-aware Steiner tree to obtain a provably near-optimal solution while keeping the time complexity low. Specifically, it runs in polynomial time and its decisions exhibit a competitive ratio of $2(1+ε)$, outperforming state-of-the-art solutions by over 50%. Our approach is also validated through a real-world implementation.
Observational Constraints on the Catastrophic Disruption Rate of Small Main Belt Asteroids
Creators: name: Denneau, Larry
name: Jedicke, Robert
name: Fitzsimmons, Alan
name: Hsieh, Henry
name: Kleyna, Jan
name: Granvik, Mikael
name: Micheli, Marco
name: Spahr, T.
name: Vereš, Peter
name: Wainscoat, Richard
name: Burgett, W. S.
name: Chambers, K. C.
name: Draper, P. W.
name: Flewelling, H.
name: Huber, M. E.
name: Kaiser, N.
name: Morgan, J. S.
name: Tonry, J. L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We have calculated 90% confidence limits on the steady-state rate of catastrophic disruptions of main belt asteroids in terms of the absolute magnitude at which one catastrophic disruption occurs per year (HCL) as a function of the post-disruption increase in brightness (delta m) and subsequent brightness decay rate (tau). The confidence limits were calculated using the brightest unknown main belt asteroid (V = 18.5) detected with the Pan-STARRS1 (Pan-STARRS1) telescope. We measured the Pan-STARRS1's catastrophic disruption detection efficiency over a 453-day interval using the Pan-STARRS moving object processing system (MOPS) and a simple model for the catastrophic disruption event's photometric behavior in a small aperture centered on the catastrophic disruption event. Our simplistic catastrophic disruption model suggests that delta m = 20 mag and 0.01 mag d-1 < tau < 0.1 mag d-1 which would imply that H0 = 28 -- strongly inconsistent with H0,B2005 = 23.26 +/- 0.02 predicted by Bottke et al. (2005) using purely collisional models. We postulate that the solution to the discrepancy is that > 99% of main belt catastrophic disruptions in the size range to which this study was sensitive (100 m) are not impact-generated, but are instead due to fainter rotational breakups, of which the recent discoveries of disrupted asteroids P/2013 P5 and P/2013 R3 are probable examples. We estimate that current and upcoming asteroid surveys may discover up to 10 catastrophic disruptions/year brighter than V = 18.5.
description: 61 Pages, 10 Figures, 3 Tables
Canadian Gallup Poll # 283
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); greatest problem facing Canada(2); Prime Minister job performance(1); US presidential elections(3); trouble spots in the world(2); preventing war(2); neutrality for Canada(2); politi parties(4); immigration to Canada(1); drinking habits(2). Note: Demographics(11).
On the orbits of a Borel subgroup in abelian ideals
Creators: name: Panyushev, Dmitri I.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Geometry (math.AG)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 14L30, 17B08, 20F55, 05E10

description: Let $B$ be a Borel subgroup of a semisimple algebraic group $G$, and let $\mathfrak a$ be an abelian ideal of $\mathfrak b=Lie(B)$. The ideal $\mathfrak a$ is determined by certain subset $Δ_{\mathfrak a}$ of positive roots, and using $Δ_{\mathfrak a}$ we give an explicit classification of the $B$-orbits in $\mathfrak a$ and $\mathfrak a^*$. Our description visibly demonstrates that there are finitely many $B$-orbits in both cases. We also describe the Pyasetskii correspondence between the $B$-orbits in $\mathfrak a$ and $\mathfrak a^*$ and the invariant algebras $\Bbbk[\mathfrak a]^U$ and $\Bbbk[\mathfrak a^*]^U$, where $U=(B,B)$. As an application, the number of $B$-orbits in the abelian nilradicals is computed. We also discuss related results of A.Melnikov and others for classical groups and state a general conjecture on the closure and dimension of the $B$-orbits in the abelian nilradicals, which exploits a relationship between between $B$-orbits and involutions in the Weyl group.
description: 24 pages
Canadian Gallup Poll # 288
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); attitudes toward Germany(2); A-bomb tests(1); religious education in public schools(2); bilingualism in public schools(2); JFK job performance(2); US Peace Corps(3); career in politics(2); federal government and unemployment(2); Canada's greatest problems(12); trial of Adolf Eichmann(4). Note: Demographics(11).
Modeling resonant trojan motion in planetary systems
Creators: name: Efthymiopoulos, C.
name: Paez, R. I.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We consider the dynamics of a small trojan companion of a hypothetical giant exoplanet under the secular perturbations of additional planets. By a suitable choice of action-angle variables, the problem is amenable to the study of the slow modulation, induced by secular perturbations, to the dynamics of an otherwise called `basic' Hamiltonian model of two degrees of freedom (planar case). We present this Hamiltonian decomposition, which implies that the slow chaotic diffusion at resonances is best described by the paradigm of modulational diffusion.
description: Accepted for publication in the proceedings of IAU Symposium 310: Complex Planetary Systems
Learning Reward Models for Cooperative Trajectory Planning with Inverse Reinforcement Learning and Monte Carlo Tree Search
Creators: name: Kurzer, Karl
name: Bitzer, Matthias
name: Zöllner, J. Marius
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Cooperative trajectory planning methods for automated vehicles can solve traffic scenarios that require a high degree of cooperation between traffic participants. However, for cooperative systems to integrate into human-centered traffic, the automated systems must behave human-like so that humans can anticipate the system's decisions. While Reinforcement Learning has made remarkable progress in solving the decision-making part, it is non-trivial to parameterize a reward model that yields predictable actions. This work employs feature-based Maximum Entropy Inverse Reinforcement Learning combined with Monte Carlo Tree Search to learn reward models that maximize the likelihood of recorded multi-agent cooperative expert trajectories. The evaluation demonstrates that the approach can recover a reasonable reward model that mimics the expert and performs similarly to a manually tuned baseline reward model.
Creation and manipulation of bound states in continuum with lasers: Applications to cold atoms and molecules
Creators: name: Deb, Bimalendu
name: Agarwal, G. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: FOS: Physical sciences

description: We show theoretically that it is possible to create and manipulate a pair of bound states in continuum in ultracold atoms by two lasers in the presence of a magnetically tunable Feshbach resonance. These bound states are formed due to coherent superposition of two electronically excited molecular bound states and a quasi-bound state in ground-state potential. These superposition states are decoupled from the continuum of two-atom collisional states. Hence, in the absence of other damping processes they are non-decaying. We analyze in detail the physical conditions that can lead to the formation of such states in cold collisions between atoms, and discuss the possible experimental signatures of such states. An extremely narrow and asymmetric shape with a distinct minimum of photoassociative absorption spectrum or scattering cross section as a function of collision energy will indicate the occurrence of a bound state in continuum (BIC). We prove that the minimum will occur at an energy at which the BIC is formed. We discuss how a BIC will be useful for efficient creation of Feshbach molecules and manipulation of cold collisions. Experimental realizations of BIC will pave the way for a new kind of bound-bound spectroscopy in ultracold atoms.
description: 26 pages 3 figures, typographical and other minor errors are corrected in version-2
Canadian Gallup Poll # 310
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); provincial government job performance(1); Prime Minister and the opposition leader job performance(2); Canadian TV approval(1); money for education(3); taxes(2); change of leadership in Russia(3); chance of world war(1); commercials on TV and radio(1). Note: Demographics(10).
Altered Metabolism and Persistent Starvation Behaviors Caused by Reduced AMPK Function in Drosophila
Creators: name: Kazgan, Nevzat
name: Worthen, Ryan J.
name: Brenman, Jay E.
name: Bretz, Colin A.
name: Onyenwoke, Rob
name: Forsberg, Lawrence J.
name: Johnson, Erik C.
name: Hector, Clare E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Organisms must utilize multiple mechanisms to maintain energetic homeostasis in the face of limited nutrient availability. One mechanism involves activation of the heterotrimeric AMP-activated protein kinase (AMPK), a cell-autonomous sensor to energetic changes regulated by ATP to AMP ratios. We examined the phenotypic consequences of reduced AMPK function, both through RNAi knockdown of the gamma subunit (AMPKγ) and through expression of a dominant negative alpha (AMPKα) variant in Drosophila melanogaster. Reduced AMPK signaling leads to hypersensitivity to starvation conditions as measured by lifespan and locomotor activity. Locomotor levels in flies with reduced AMPK function were lower during unstressed conditions, but starvation-induced hyperactivity, an adaptive response to encourage foraging, was significantly higher than in wild type. Unexpectedly, total dietary intake was greater in animals with reduced AMPK function yet total triglyceride levels were lower. AMPK mutant animals displayed starvation-like lipid accumulation patterns in metabolically key liver-like cells, oenocytes, even under fed conditions, consistent with a persistent starved state. Measurements of O2 consumption reveal that metabolic rates are greater in animals with reduced AMPK function. Lastly, rapamycin treatment tempers the starvation sensitivity and lethality associated with reduced AMPK function. Collectively, these results are consistent with models that AMPK shifts energy usage away from expenditures into a conservation mode during nutrient-limited conditions at a cellular level. The highly conserved AMPK subunits throughout the Metazoa, suggest such findings may provide significant insight for pharmaceutical strategies to manipulate AMPK function in humans.
Canadian Gallup Poll # 353
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); labor productivity in Canada(2); inflation and unemployment(3); Canada's dependence on US(1); bilingualism(2); human rights(2); Canada-US agreement to clean Great Lakes(2); federal government job performance(2); current party preference(1). Note: Demographics(9). Not included: religion, family status.
Filling an emulsion drop with motile bacteria
Creators: name: Vladescu, I. D.
name: Marsden, E. J.
name: Schwarz-Linek, J.
name: Martinez, V. A.
name: Arlt, J.
name: Morozov, A. N.
name: Marenduzzo, D.
name: Cates, M. E.
name: Poon, W. C. K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We have measured the spatial distribution of motile Escherichia coli inside spherical water droplets emulsified in oil. At low cell concentrations, the cell density peaks at the water-oil interface; at increasing concentration, the bulk of each droplet fills up uniformly while the surface peak remains. Simulations and theory show that the bulk density results from a `traffic' of cells leaving the surface layer, increasingly due to cell-cell scattering as the surface coverage rises above $\sim 10\%$. Our findings show similarities with the physics of a rarefied gas in a spherical cavity with attractive walls.
description: 5 pages, 4 figures, Supporting Information (5 pages, 5 figures)
Comparison of Electron Capture Rates in the N=50 Region using 1D Simulations of Core-collapse Supernovae
Creators: name: Johnston, Zac
name: Wasik, Sheldon
name: Titus, Rachel
name: Warren, MacKenzie L.
name: O'Connor, Evan P.
name: Zegers, Remco
name: Couch, Sean M.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Recent studies have highlighted the sensitivity of core-collapse supernovae (CCSNe) models to electron-capture (EC) rates on neutron-rich nuclei near the N=50 closed-shell region. In this work, we perform a large suite of one-dimensional CCSN simulations for 200 stellar progenitors using recently updated EC rates in this region. For comparison, we repeat the simulations using two previous implementations of EC rates: a microphysical library with parameterized N=50 rates (LMP), and an older independent-particle approximation (IPA). We follow the simulations through shock revival up to several seconds post-bounce, and show that the EC rates produce a consistent imprint on CCSN properties, often surpassing the role of the progenitor itself. Notable impacts include the timescale of core collapse, the electron fraction and mass of the inner core at bounce, the accretion rate through the shock, the success or failure of revival, and the properties of the central compact remnant. We also compare the observable neutrino signal of the neutronization burst in a DUNE-like detector, and find consistent impacts on the counts and mean energies. Overall, the updated rates result in properties that are intermediate between LMP and IPA, and yet slightly more favorable to explosion than both.
description: 14 pages, 8 figures, 1 table. Updated Fig 5, minor corrections, renamed SNA to IPA. Accepted by ApJ
An Agent-Based Model of Signal Transduction in Bacterial Chemotaxis
Creators: name: Miller, Jameson
name: Giddings, Morgan C.
name: Bourret, Robert B.
name: Parker, Miles
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: We report the application of agent-based modeling to examine the signal transduction network and receptor arrays for chemotaxis in Escherichia coli, which are responsible for regulating swimming behavior in response to environmental stimuli. Agent-based modeling is a stochastic and bottom-up approach, where individual components of the modeled system are explicitly represented, and bulk properties emerge from their movement and interactions. We present the Chemoscape model: a collection of agents representing both fixed membrane-embedded and mobile cytoplasmic proteins, each governed by a set of rules representing knowledge or hypotheses about their function. When the agents were placed in a simulated cellular space and then allowed to move and interact stochastically, the model exhibited many properties similar to the biological system including adaptation, high signal gain, and wide dynamic range. We found the agent based modeling approach to be both powerful and intuitive for testing hypotheses about biological properties such as self-assembly, the non-linear dynamics that occur through cooperative protein interactions, and non-uniform distributions of proteins in the cell. We applied the model to explore the role of receptor type, geometry and cooperativity in the signal gain and dynamic range of the chemotactic response to environmental stimuli. The model provided substantial qualitative evidence that the dynamic range of chemotactic response can be traced to both the heterogeneity of receptor types present, and the modulation of their cooperativity by their methylation state.
Automatic Generation of Individual Fuzzy Cognitive Maps from Longitudinal Data
Creators: name: Wozniak, Maciej K
name: Mkhitaryan, Samvel
name: Giabbanelli, Philippe j.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Fuzzy Cognitive Maps (FCMs) are computational models that represent how factors (nodes) change over discrete interactions based on causal impacts (weighted directed edges) from other factors. This approach has traditionally been used as an aggregate, similarly to System Dynamics, to depict the functioning of a system. There has been a growing interest in taking this aggregate approach at the individual-level, for example by equipping each agent of an Agent-Based Model with its own FCM to express its behavior. Although frameworks and studies have already taken this approach, an ongoing limitation has been the difficulty of creating as many FCMs as there are individuals. Indeed, current studies have been able to create agents whose traits are different, but whose decision-making modules are often identical, thus limiting the behavioral heterogeneity of the simulated population. In this paper, we address this limitation by using Genetic Algorithms to create one FCM for each agent, thus providing the means to automatically create a virtual population with heterogeneous behaviors. Our algorithm builds on prior work from Stach and colleagues by introducing additional constraints into the process and applying it over longitudinal, individual-level data. A case study from a real-world intervention on nutrition confirms that our approach can generate heterogeneous agents that closely follow the trajectories of their real-world human counterparts. Future works include technical improvements such as lowering the computational time of the approach, or case studies in computational intelligence that use our virtual populations to test new behavior change interventions.
Antiretroviral Intensification and Valproic Acid Lack Sustained Effect on Residual HIV-1 Viremia or Resting CD4+ Cell Infection
Creators: name: Eron, Joseph
name: Bosch, Ronald J.
name: Parker, Daniel
name: Cheema, Manzoor
name: Cohen, Myron
name: Wiegand, Ann
name: Margolis, David M.
name: Archin, Nancie M.
name: Coffin, John M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: BackgroundHuman immunodeficiency virus (HIV) infection that persists despite antiretroviral therapy (ART) is a daunting problem. Given the limited evidence that resting CD4+ T cell infection (RCI) is affected by the histone deacetylase (HDAC) inhibitor valproic acid (VPA), we measured the stability of RCI and residual viremia in patients who added VPA with or without raltegravir (RAL), or enfuvirtide (ENF) with or without VPA, to standard ART.MethodsPatients with plasma HIV RNA<50 c/mL added sustained-release VPA (Depakote ER®) twice daily, RAL 400 mg twice daily, or ENF 90 mcg twice daily. Change in RCI was measured by outgrowth assays. Low-level viremia was quantitated by single-copy plasma HIV RNA assay (SCA).ResultsIn three patients on standard ART a depletion of RCI was observed after 16 weeks of VPA, but this effect waned over up to 96 weeks of further VPA. In two patients ENF added to stable ART had no effect on RCI. Simultaneous intensification with ENF and addition of VPA had no effect on RCI frequency in one patient, and resulted in a 46% decline in a second. No significant depletion of RCI (>50%) was seen in six volunteers after the addition of RAL and VPA. In 4 of the 6 patients this lack of effect might be attributed to intermittent viremia, low VPA levels, or intermittent study therapy adherence. Overall, there was no effect of the addition of RAL or ENF on low-level viremia measured by SCA.ConclusionsThe prospective addition of VPA and RAL, VPA and ENF, or ENF failed to progressively reduce the frequency of RCI, or ablate intermittent and low-level viremia. New approaches such as more potent HDAC inhibition, alone or in combination with intensified ART or other agents that may disrupt proviral latency must be pursued.
Dissipation of oscillating scalar backgrounds in an FLRW universe
Creators: name: Wang, Zi-Liang
name: Ai, Wen-Yuan
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the dissipation of oscillating scalar backgrounds in a spatially flat Friedmann-Lemaître-Robertson-Walker universe using non-equilibrium quantum field theory. To be concrete, a $Z_2$-symmetric two-scalar model with quartic interactions is used. For quasi-harmonic oscillations, we adopt the multi-scale analysis to obtain analytical approximate expressions for the evolution of the scalar background in terms of the retarded self-energy and retarded proper four-vertex function. Different from the case in flat spacetime, we find that in an expanding universe the condensate decay in this model can be complete only if the imaginary part of the retarded self-energy is not negligibly small. The microphysical interpretation of the imaginary parts of the retarded self-energy and retarded proper four-vertex function in terms of particle production is also discussed.
description: 32 pages + appendix, 18 figures; v2: minor typos corrected; v3: clarifying comments added; v4: time-dependence of the microscopic quantities discussed, refs updated, to appear in JHEP; v5: matches the published version
Canadian Gallup Poll # 360
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); minimum family income(1); federal government and social groups(4); Cabinet ministers approval(2); gas and oil shortage(4); Medicare(2); education, leisure time(2); Watergate affair(3). Note: Demographics(10).
Association between DNA Damage Response and Repair Genes and Risk of Invasive Serous Ovarian Cancer
Creators: name: Whitaker, Regina
name: Clyde, Merlise A.
name: Schildkraut, Joellen M.
name: Wilson, Melanie A.
name: Bentley, Rex C.
name: Marks, Jeffrey R.
name: Palmieri, Rachel T.
name: Berchuck, Andrew
name: Iversen, Edwin S.
name: Moorman, Patricia G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: BackgroundWe analyzed the association between 53 genes related to DNA repair and p53-mediated damage response and serous ovarian cancer risk using case-control data from the North Carolina Ovarian Cancer Study (NCOCS), a population-based, case-control study.Methods/Principal FindingsThe analysis was restricted to 364 invasive serous ovarian cancer cases and 761 controls of white, non-Hispanic race. Statistical analysis was two staged: a screen using marginal Bayes factors (BFs) for 484 SNPs and a modeling stage in which we calculated multivariate adjusted posterior probabilities of association for 77 SNPs that passed the screen. These probabilities were conditional on subject age at diagnosis/interview, batch, a DNA quality metric and genotypes of other SNPs and allowed for uncertainty in the genetic parameterizations of the SNPs and number of associated SNPs. Six SNPs had Bayes factors greater than 10 in favor of an association with invasive serous ovarian cancer. These included rs5762746 (median OR(odds ratio)per allele = 0.66; 95% credible interval (CI) = 0.44–1.00) and rs6005835 (median ORper allele  = 0.69; 95% CI  = 0.53–0.91) in CHEK2, rs2078486 (median ORper allele  = 1.65; 95% CI = 1.21–2.25) and rs12951053 (median ORper allele  = 1.65; 95% CI = 1.20–2.26) in TP53, rs411697 (median OR rare homozygote  = 0.53; 95% CI  = 0.35 – 0.79) in BACH1 and rs10131 (median OR rare homozygote  =  not estimable) in LIG4. The six most highly associated SNPs are either predicted to be functionally significant or are in LD with such a variant. The variants in TP53 were confirmed to be associated in a large follow-up study.Conclusions/SignificanceBased on our findings, further follow-up of the DNA repair and response pathways in a larger dataset is warranted to confirm these results.
Canadian Gallup Poll # 281
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); lotteries run by government(2); job opportunities for married women(3); marriage(3); the best country in the world(20); UN and the "population explosion"(3); bank credit(2); greatest problem facing Canada(2); divorce(2).
Photocatalytic stannylation of white phosphorus
Creators: name: Till, Marion
name: Cammarata, Jose
name: Wolf, Robert
name: Scott, Daniel J.
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: 540 Chemie

description: Organophosphorus compounds (OPCs) are highly important chemicals, finding numerous applications in both academia and industry. Herein we describe a simple photocatalytic method for the stannylation of white phosphorus (P4) using a cheap, commercially-available distannane, (Bu3Sn)2, and anthraquinone as a simple photocatalyst. Subsequent ‘one pot’ transformation of the resulting stannylated monophosphine intermediate (Bu3Sn)3P provides direct, convenient and versatile access to valuable OPCs such as acylated phosphines and tetraalkylphosphonium salts.
(:unas) unassigned
Creators: name: (:Unkn) Unknown
Publisher: name: Universita' degli Studi di Salerno
Year: 2024

description: This article projects to comparatively study the construction of antirepresentational visual ‘other spaces’ in René Magritte’s The Treachery of Im ages, a painting that destabilizes and mocks rep resentationalism on canvas, and Samuel Beckett’s Endgame, a play that performs a similar gesture on stage. Magritte and Beckett play on the bound aries that have traditionally separated the visible and the invisible in the visual arts and the theatre and construct some heterogenous spaces that de stabilize the viewers’/spectators’ linear perspec tival search for meaning. This is to be done by means of a critical re-appropriation of Foucault’s concept of heterotopia that he coined to refer to language’s ability to construct and juxtapose a multiplicity of spaces that both diverge and con verge. It is to be noted that the term was devised by the French thinker to refer, exclusively, to lin guistic spaces. The article seeks to transpose het erotopia from the purely linguistic to the visual. The aim is to show that there is in Magritte and Beckett a self-reflexive gaming with artistic crea tivity as a process through the creation of visual heterotopias. The focus is accordingly put on the twofold use of aesthetics in art/ theatre to decen tralize knowledge and the real, on the one hand, and put into doubt the very means through which they have historically operated, on the other.
ПСИХОЛОГИЯ СТРЕССОВЫХ СИТУАЦИЙ У СОЦИАЛЬНО НЕЗАЩИЩЕННЫХ ПОДРОСТКОВ
Creators: name: Хашимова, Сайёра
Publisher: name: Zenodo
Year: 2023

description: В статья направлена на то, чтобы лучше понять масштабы и характер исследовательской деятельности по теме проблем психического здоровья у молодых людей с физическими недостатками, начавшимися в детстве а также даны понятия «стресс», рассматривается влияние стресса на жизнь человека, описываются основные признаки того, что человек испытывает стресс и методы его профилактики.
Quantum Computing for Software Engineering: Prospects
Creators: name: Miranskyy, Andriy
name: Khan, Mushahid
name: Faye, Jean Paul Latyr
name: Mendes, Udson C.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Software Engineering (cs.SE)
subject: Emerging Technologies (cs.ET)
subject: FOS: Computer and information sciences

description: Quantum computers (QCs) are maturing. When QCs are powerful enough, they may be able to handle problems in chemistry, physics, and finance that are not classically solvable. However, the applicability of quantum algorithms to speed up Software Engineering (SE) tasks has not been explored. We examine eight groups of quantum algorithms that may accelerate SE tasks across the different phases of SE and sketch potential opportunities and challenges.
Optimal Stabilization using Lyapunov Measures
Creators: name: Raghunathan, Arvind
name: Vaidya, Umesh
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optimization and Control (math.OC)
subject: Systems and Control (eess.SY)
subject: FOS: Mathematics
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Numerical solutions for the optimal feedback stabilization of discrete time dynamical systems is the focus of this paper. Set-theoretic notion of almost everywhere stability introduced by the Lyapunov measure, weaker than conventional Lyapunov function-based stabilization methods, is used for optimal stabilization. The linear Perron-Frobenius transfer operator is used to pose the optimal stabilization problem as an infinite dimensional linear program. Set-oriented numerical methods are used to obtain the finite dimensional approximation of the linear program. We provide conditions for the existence of stabilizing feedback controls and show the optimal stabilizing feedback control can be obtained as a solution of a finite dimensional linear program. The approach is demonstrated on stabilization of period two orbit in a controlled standard map.
Cooperative Trajectory Planning in Uncertain Environments with Monte Carlo Tree Search and Risk Metrics
Creators: name: Stegmaier, Philipp
name: Kurzer, Karl
name: Zöllner, J. Marius
Publisher: name: arXiv
Year: 2022
Subjects: subject: Multiagent Systems (cs.MA)
subject: Artificial Intelligence (cs.AI)
subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Automated vehicles require the ability to cooperate with humans for smooth integration into today's traffic. While the concept of cooperation is well known, developing a robust and efficient cooperative trajectory planning method is still a challenge. One aspect of this challenge is the uncertainty surrounding the state of the environment due to limited sensor accuracy. This uncertainty can be represented by a Partially Observable Markov Decision Process. Our work addresses this problem by extending an existing cooperative trajectory planning approach based on Monte Carlo Tree Search for continuous action spaces. It does so by explicitly modeling uncertainties in the form of a root belief state, from which start states for trees are sampled. After the trees have been constructed with Monte Carlo Tree Search, their results are aggregated into return distributions using kernel regression. We apply two risk metrics for the final selection, namely a Lower Confidence Bound and a Conditional Value at Risk. It can be demonstrated that the integration of risk metrics in the final selection policy consistently outperforms a baseline in uncertain environments, generating considerably safer trajectories.
Canadian Gallup Poll # 333
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); personal savings(2); propaganda war between Russia and US(1); discipline in public schools(2); Canada and two party system(1); federal government job performance(1). Note: Demographics(11).
Association of rs780094 in GCKR with Metabolic Traits and Incident Diabetes and Cardiovascular Disease: The ARIC Study
Creators: name: Astor, Brad C.
name: Hoogeveen, Ron C.
name: Rasmussen-Torvik, Laura J.
name: Coresh, Josef
name: Köttgen, Anna
name: Bi, Mark
name: Kao, Wen Hong Linda
name: Boerwinkle, Eric
name: North, Kari E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: ObjectiveThe minor T-allele of rs780094 in the glucokinase regulator gene (GCKR) associates with a number of metabolic traits including higher triglyceride levels and improved glycemic regulation in study populations of mostly European ancestry. Using data from the Atherosclerosis Risk in Communities (ARIC) Study, we sought to replicate these findings, examine them in a large population-based sample of African American study participants, and to investigate independent associations with other metabolic traits in order to determine if variation in GKCR contributes to their observed clustering. In addition, we examined the association of rs780094 with incident diabetes, coronary heart disease (CHD), and stroke over up mean follow-up times of 8, 15, and 15 years, respectively.Research Design and MethodsRace-stratified analyses were conducted among 10,929 white and 3,960 black participants aged 45–64 at baseline assuming an additive genetic model and using linear and logistic regression and Cox proportional hazards models.ResultsPrevious findings replicated among white participants in multivariable adjusted models: the T-allele of rs780094 was associated with lower fasting glucose (p = 10−7) and insulin levels (p = 10−6), lower insulin resistance (HOMA-IR, p = 10−9), less prevalent diabetes (p = 10−6), and higher CRP (p = 10−8), 2-h postprandial glucose (OGTT, p = 10−6), and triglyceride levels (p = 10−31). Moreover, the T-allele was independently associated with higher HDL cholesterol levels (p = 0.022), metabolic syndrome prevalence (p = 0.043), and lower beta-cell function measured as HOMA-B (p = 0.011). Among black participants, the T-allele was associated only with higher triglyceride levels (p = 0.004) and lower insulin levels (p = 0.002) and HOMA-IR (p = 0.013). Prospectively, the T-allele was associated with reduced incidence of diabetes (p = 10−4) among white participants, but not with incidence of CHD or stroke.ConclusionsOur findings indicate rs780094 has independent associations with multiple metabolic traits as well as incident diabetes, but not incident CHD or stroke. The magnitude of association between the SNP and most traits was of lower magnitude among African American compared to white participants.