cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplementary document for On the use of a consumer-grade 360-degree camera as a radiometer for scientific applications - 7152786.pdf
Creators: name: Larouche, Raphael
name: Girard, Simon Lambert
name: Katlein, Christian
name: Marty, Sabine
name: Leymarie, Edouard
name: Thibault, Simon
name: Babin, Marcel
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Calibration and real-world validation supplements
Supplementary document for High-speed 2D materials inspection using microscopic dynamic spectroscopic imaging ellipsometer - 7152980.pdf
Creators: name: choi, sukhyun
name: Woo, Chae Young
name: HWANG, GUKHYEON
name: Kheiryzadehkhanghah, Saeid
name: Choi, Inho
name: Cho, Yong Jai
name: Lee, Hyung Woo
name: Chegal, Won
name: Kim, Daesuk
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized
Nanomaterials

description: Supplemental Document for Data file
Eating disorder behaviors and treatment seeking in self-identified military personnel and veterans: Results of the National Eating Disorders Association online screening
Creators: name: Wilfley, Denise E
name: Flatt, Rachael E
name: Bulik, Cynthia M
name: Norman, Elliott
name: Mysko, Claire
name: Smolar, Lauren
name: Thornton, Laura M
name: Balantekin, Katherine N
name: Fitzsimmons-Craft, Ellen E
name: Taylor, C Barr
Publisher: name: Elsevier
Year: 2021

description: OBJECTIVE: To characterize disordered eating behaviors, eating disorder (ED) risk and diagnosis, and treatment seeking behaviors in active-duty military personnel/veterans compared with civilians. METHOD: Self-selecting participants (n = 113,388; 1744 were military personnel/veterans) 18+ years old completed the National Eating Disorders Association's online screen. Engagement in and frequencies of disordered eating behaviors were compared across military/veteran and civilian groups and were stratified by gender. ED risk and diagnosis and treatment seeking behaviors were also compared. RESULTS: Individuals in the military/veteran group were more likely to engage in diuretic/laxative use and excessive exercise compared with civilians. Compared with civilians, the military/veteran group had a lower percentage who screened "at risk for an ED" and a higher percentage who screened for "no risk". Females in the military/veteran group were more likely to engage in diuretic/laxative use, excessive exercise, and fasting compared with female civilians; males in the military/veteran group were more likely to engage in excessive exercise and less likely to engage in vomiting than male civilians. Of the self-identified military personnel/veterans who screened positive for any ED, 86% had never received treatment, which did not differ significantly from civilians. Notably, 56.7% of those (54.1% of military/veteran group; 56.7% of civilians) who completed an optional item on intention to seek treatment (n = 5312) indicated they would not seek treatment. CONCLUSIONS: Disordered eating and ED profiles, but not treatment seeking, may differ between military personnel/veterans and civilians who complete an online ED screen. Future work should emphasize treatment options and connecting respondents directly to tailored resources.
Supplementary document for Terahertz polarization conversion and asymmetric transmission based on liquid crystal integrated EIT metasurface - 7153202.pdf
Creators: name: Xu, Shi-Tong
name: Fan, Junxing
name: Xue, Zhanqiang
name: Li, Jiandi
name: Wang, Ying-Hua
name: Pan, Yue
name: Cao, Hong-Zhong
name: Ma, Rende
name: Lu, Dan
name: Zhang, Huifang
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: See Supplement 1 for supporting content.
Supplemental Material, JCR_Appendix - What Determines Perceptions of Bias toward the International Criminal Court? Evidence from Kenya
Creators: name: Dancy, Geoff
name: Dutton, Yvonne Marie
name: Alleblas, Tessa
name: Aloyo, Eamon
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 220104 Human Rights and Justice Issues
subject: FOS: Philosophy, ethics and religion
subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material, JCR_Appendix for What Determines Perceptions of Bias toward the International Criminal Court? Evidence from Kenya by Geoff Dancy, Yvonne Marie Dutton, Tessa Alleblas and Eamon Aloyo in Journal of Conflict Resolution
File 6
Creators: name: Schnabl-Feichter, Eva
name: Schnabl, Sophia
name: Tichy, Alexander
name: Gumpenberger, Michaela
name: Bockstahler, Barbara
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Cats with femoral head and neck excision – results of the radiographic examination
Supplementary document for A portable, smartphone-linked, and miniaturized Photonic Resonator Absorption Microscope (PRAM Mini) for point-of-care diagnostics - 7153281.pdf
Creators: name: Khemtonglang, Kodchakorn
name: Liu, Weinan
name: Lee, Hankeun
name: Wang, Weijing
name: Li, Siyan
name: Li, James
name: Shepherd, Skye
name: Diel, Diego
name: Fang, Ying
name: Cunningham, Brian
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Photonics and Electro-Optical Engineering (excl. Communications)

description: CAD drawings of the optical fixtures, Application user interfaces, Photographs of internal design, Video screenshots of the DDC application, and source codes for camera control and counting algorithm
Effect of Feed Water pH on the Partitioning of Alkali Metal Salts from Aqueous Phase into the Polyamide Active Layers of Reverse Osmosis Membranes
Creators: name: Grzebyk, Kasia
name: Coronell, Orlando
name: Armstrong, Mikayla D.
name: Wang, Jingbo
name: Vickers, Riley
Publisher: name: American Chemical Society (ACS)
Year: 2021

description: The partitioning of solutes into the polyamide active layers of reverse osmosis (RO) membranes is a key membrane property determining solute permeation. Quantification of partition coefficients and their dependence on feedwater pH would contribute to the development of predictive transport models of contaminant transport through RO membranes; however, neither solute partitioning nor the effect of feed solution pH on partitioning has been thoroughly characterized in the literature. Accordingly, we characterized the partitioning of all chloride salts of alkali metals (CsCl, RbCl, KCl, NaCl, and LiCl) from the aqueous phase into the polyamide active layers of five polyamide RO membranes, including one prepared in-house and four commercial membranes. We evaluated the effect of pH on the partitioning of alkali metal salts and whether the effect of pH on salt partitioning and rejection is consistent with Donnan theory predictions. Results showed that for all membranes, the partition coefficients of all salts were less than one and did not differ substantially among RO membranes. Results also indicated that for all membranes tested, Donnan theory provided an appropriate theoretical framework to estimate the effect of pH on salt partitioning (evaluated for all chloride salts of alkali metals) and salt rejection (evaluated for NaCl). Thus, we conclude that changes in salt rejection resulting from feed solution pH are primarily driven by changes in salt partitioning with comparatively small changes in salt diffusion coefficients.
Supplementary document for Design, simulation and experimental realization of a novel high-sensitivity polarization-independent electromagnetically induced transparent terahertz metamaterials. - 7153344.pdf
Creators: name: Lei, Jiangtao
name: Zhou, Xinwei
name: Li, Le
name: Shen, Yun
name: Hong, Lujun
name: Guo, Tianjing
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: supplementary document
Effects of Ligand Shell Composition on Surface Reduction in PbS Quantum Dots
Creators: name: Dempsey, Jillian L.
name: Camp, Andrew M.
name: Kessler, Melody L.
name: Lassalle, Christian Y. Dones
name: Hartley, Carolyn L.
Publisher: name: American Chemical Society (ACS)
Year: 2021

description: Quantum dots (QDs) are semiconductor nanocrystals with optical properties that can be tuned through postsynthetic ligand exchanges. Importantly, the stability of QD surfaces in optoelectronic devices is influenced by the ligand shell composition and the structure of the exchange ligand. QDs incorporated into such devices are frequently exposed to excess electronic charges that can localize at the surface via doping, charge hopping, etc. However, changes in the reactivity and stability of QDs upon surface reduction as a function of ligand shell composition are not well understood. In this work, we evaluated the impacts of both surface-binding head group and ligand backbone on the properties and reactivity of PbS QDs through a partial exchange of native oleate ligands with undec-10-enoic acid, p-toluate, and undec-10-ene-1-thiol to access mixed-shell QDs. We compared the reactivity and stability of these mixed-shell QDs in response to surface reduction via the addition of a molecular reductant, cobaltocene (CoCp2). Upon reaction with CoCp2, X-type ligand displacement from the QD surface was observed in each of the mixed-shell systems and monitored via 1H NMR spectroscopy. Comparative studies reveal that indiscriminate and moderate ligand displacement occurs from QDs capped with long-chain carboxylate ligands (ca. 10% ligands displaced), while more dramatic (ca. 20-30%) and preferential displacement of aryl ligands occurs with a mixed shell of alkyl and aryl carboxylates. In contrast, QDs capped with a mix of thiolate, thiol, and carboxylate ligands only exhibit displacement of carboxylate ligands. Overall, this work demonstrates that the extent of surface reduction induced by the addition of a molecular reductant is highly sensitive to the composition of the QD ligand shell.
Efficient and Highly Specific Gene Transfer Using Mutated Lentiviral Vectors Redirected with Bispecific Antibodies
Creators: name: Jacobs, Timothy M.
name: Lai, Samuel K.
name: Harit, Dimple
name: Parker, Christina L.
name: Huckaby, Justin T.
Publisher: name: American Society for Microbiology
Year: 2020

description: Despite their exceptional potencies, the broad tropism of most commonly used lentivirus (LV) vectors limits their use for targeted gene delivery in vivo We hypothesized that we could improve the specificity of LV targeting by coupling (i) reduction of their binding to off-target cells with (ii) redirection of the vectors with a bispecific antibody (bsAb) that binds both LV and receptors on target cells. As a proof of concept, we pseudotyped nonreplicating LV using a mutated Sindbis envelope (mSindbis) with ablated binding to native receptors, while retaining the capacity to facilitate efficient fusion and endosomal escape. We then evaluated the transduction potencies of the mSindbis LV for HER2-positive (HER2+) (SKBR3) breast and HER2-negative (HER2-) (A2780) cells when redirected with different bsAbs. mSindbis LV alone failed to induce appreciable green fluorescent protein (GFP) expression in either cell. When mixed with HER2-targeting bsAb, mSindbis LV was exceptionally potent, transducing 12% to 16% of the SKBR3 cells at a multiplicity of infection (MOI [ratio of viral genome copies to target cells]) of 3. Transduction was highly specific, resulting in ~50-fold-greater selectivity toward SKBR3 cells versus A2780 cells. Redirecting mSindbis LV led to a 10-fold improvement in cell-specific targeting compared to redirecting wild-type Sindbis LV with the same bsAb, underscoring the importance of ablating native virus tropism in order to maximize targeting specificity. The redirection of mutated LV using bsAb represents a potent and highly versatile platform for targeted gene therapy.IMPORTANCE The goal of gene therapy is specific delivery and expression of therapeutic genes to target cells and tissues. Common lentivirus (LV) vectors are efficient gene delivery vehicles but offer little specificity. Here, we report an effective and versatile strategy to redirect LV to target cells using bispecific antibodies (bsAbs) that bind both cell receptors and LV envelope domains. Importantly, we ablated the native receptor binding of LV to minimize off-target transduction. Coupling bsAb specificity and ablated native LV tropism synergistically enhanced the selectivity of our targeted gene delivery system. The modular nature of our bsAb-based redirection enables facile targeting of the same LV to diverse tissues/cells. By abrogating the native broad tropism of LV, our bsAb-LV redirection strategy may enable lentivirus-based gene delivery in vivo, expanding the current use of LV beyond ex vivo applications.
Supplementary document for Magnetic tuning with minimal thermal drift in a high-Q magnetorheological polydimethylsiloxane coated μ-sphere - 7153401.pdf
Creators: name: Jin, Xiaolin
name: Chen, Mengmeng
name: ZHENG, JIHUI
name: Xu, Enming
name: Jiang, Chen
name: Zhou, Kaiming
name: Sun, Bing
name: Zhang, Zuxing
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Figures
Additional file 1 of Del-Nido cardioplegia in cardiac surgery for elderly patients: a propensity score-matched analysis
Creators: name: Gu, Wenda
name: Qing, Hongkun
name: Luo, Xiang
name: Zang, Xin
name: Zhou, Kan
name: Guo, Haijiang
name: Zhou, Chengbin
name: Guo, Huiming
name: Liu, Jian
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Biological Sciences not elsewhere classified
Marine Biology
Science Policy

description: Additional File: Formula of cardioplegia
Supplementary document for CRISPR/Cas12a Cleavage Triggered magnetic nanoflower for fluorescence-free and target amplification-free biosensing of ctDNA in the terahertz frequencies - 7153553.pdf
Creators: name: Zhao, Jingjing
name: zhu, Jianfang
name: Wang, Weiqiang
name: Qian, Zhengfang
name: Fan, Shuting
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary 1
Efficient test-based variable selection for high-dimensional linear models
Creators: name: Liu, Yufeng
name: Gong, Siliang
name: Zhang, Kai
Publisher: name: Elsevier
Year: 2018

description: Variable selection plays a fundamental role in high-dimensional data analysis. Various methods have been developed for variable selection in recent years. Well-known examples are forward stepwise regression (FSR) and least angle regression (LARS), among others. These methods typically add variables into the model one by one. For such selection procedures, it is crucial to find a stopping criterion that controls model complexity. One of the most commonly used techniques to this end is cross-validation (CV) which, in spite of its popularity, has two major drawbacks: expensive computational cost and lack of statistical interpretation. To overcome these drawbacks, we introduce a flexible and efficient test-based variable selection approach that can be incorporated into any sequential selection procedure. The test, which is on the overall signal in the remaining inactive variables, is based on the maximal absolute partial correlation between the inactive variables and the response given active variables. We develop the asymptotic null distribution of the proposed test statistic as the dimension tends to infinity uniformly in the sample size. We also show that the test is consistent. With this test, at each step of the selection, a new variable is included if and only if the p-value is below some pre-defined level. Numerical studies show that the proposed method delivers very competitive performance in terms of variable selection accuracy and computational complexity compared to CV.
Supplementary document for Tapered Coreless Optical Fiber-based Refractive Index Sensor for Acetone Concentration Detection - 7153596.pdf
Creators: name: Kadhum, Yosra
name: Salman, Ansam
name: Al-Janabi, Abdulhadi
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: supplemental figures
Supplementary document for Tapered Coreless Optical Fiber-based Refractive Index Sensor for Acetone Concentration Detection - 7153596.pdf
Creators: name: Kadhum, Yosra
name: Salman, Ansam
name: Al-Janabi, Abdulhadi
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: supplemental figures
Electric Fields Detected on Dye-Sensitized TiO2 Interfaces: Influence of Electrolyte Composition and Ruthenium Polypyridyl Anchoring Group Type
Creators: name: Meyer, Gerald J.
name: Davis, Victoria K.
name: Sampaio, Renato N.
name: Marquard, Seth L.
Publisher: name: American Chemical Society (ACS)
Year: 2018

description: Electric fields at the dye-sensitized interface of anatase TiO2 nanocrystallites interconnected in a mesoporous thin film are reported using carboxylic acid-derivatized and phosphonic acid-derivatized ruthenium polypyridyl complexes. Systematic investigations with [Ru­(dtb)2(dpb)]­(PF6)2, where dtb is 4,4'-di-tert-butyl-2,2'-bipyridine and dpb is 4,4'-bis-(PO3H2)-2,2'-bipyridine, were carried out in conjunction with its carboxylic acid structural analogue. Electric fields attributed to cation adsorption were measured from a bathochromic (red) shift of the sensitizer's UV-visible absorption spectra upon replacement of neat acetonitrile solution with metal cation perchlorate acetonitrile electrolyte. Electric fields attributed to TiO2 electrons were measured from the hypsochromic (blue) shift of the absorption spectra upon electrochemical reduction of the sensitized TiO2 thin films. Electric fields, induced by either cation adsorption or electrochemically populated electrons, increase in magnitude following the same general cation-dependent trend (Na+ < Li+ < Ca2+ ≤ Mg2+ < Al3+), regardless of the sensitizer's anchoring group type. For the first time, surface electric fields in the presence of trivalent cations (i.e., Al3+) were measured using [Ru­(dtb)2(dpb)]­(PF6)2. The magnitude of electric fields detected by the carboxylic acid sensitizer was 3 times greater than that detected by the phosphonic acid structural analogue under the same experimental conditions. The influence of protons and water in the acetonitrile electrolyte was also quantified. The added water was found to decrease the electric field, whereas protons had a very similar influence as did metal cations.
Electron Localization and Transport in SnO2/TiO2 Mesoporous Thin Films: Evidence for a SnO2/Sn x Ti1-x O2/TiO2 Structure
Creators: name: Bangle, Rachel E.
name: Bennett, Marc T.
name: Meyer, Gerald J.
name: James, Erica M.
Publisher: name: American Chemical Society (ACS)
Year: 2019

description: A study of SnO2/TiO2 core/shell films was undertaken to investigate the influences of shell thickness and post deposition sintering on electron localization and transport properties. Electrochemical reduction of the materials resulted in the appearance of a broad visible-near IR absorbance that provided insights into the electronic state(s) within the core/shell structures. As the shell thickness was increased from 0.5 to 5 nm, evidence for the presence of a SnxTi1-xO2 interfacial state emerged that was physically located between the core and the shell. The lifetime of photoinjected electrons increased with the shell thickness. Electron transport occurred through the SnO2 core; however, when materials with shell thicknesses ≥2 nm were annealed at 450 °C, a new electron transport pathway through the shell was evident. The data indicate that these materials are best described as SnO2/SnxTi1-xO2/TiO2 where electrons preferentially localize in a SnxTi1-xO2 interfacial state and transport through SnO2 and annealed TiO2 (if present). The implications of these results for applications in solar energy conversion are discussed.
Supplementary_text_2 – Supplemental material for Exposure matters: forest dynamics reveal an early Holocene conifer refugium on a north facing slope in Central Europe
Creators: name: Pató, Zsuzsanna Anna
name: Standovár, Tibor
name: Gałka, Mariusz
name: Jakab, Gusztáv
name: Molnár, Mihály
name: Szmorad, Ferenc
name: Enikő Magyari
Publisher: name: SAGE Journals
Year: 2020
Subjects: Geography
History

description: Supplemental material, Supplementary_text_2 for Exposure matters: forest dynamics reveal an early Holocene conifer refugium on a north facing slope in Central Europe by Zsuzsanna Anna Pató, Tibor Standovár, Mariusz Gałka, Gusztáv Jakab, Mihály Molnár, Ferenc Szmorad and Enikő Magyari in The Holocene
Supplementary document for Multimodal Nonlinear Optical Microscope for Material and Life Sciences - 7153656.pdf
Creators: name: Tomberg, Teemu
name: Isomäki, Antti
name: Vainio, Markku
name: Metsälä, Markus
name: Saarinen, Jukka
name: Strachan, Clare
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Optical Technology

description: Supplemental information
Electron Transfer Reorganization Energies in the Electrode-Electrolyte Double Layer
Creators: name: Meyer, Gerald J.
name: Piechota, Eric J.
name: Schneider, Jenny
name: Troian-Gautier, Ludovic
name: Bangle, Rachel E.
Publisher: name: American Chemical Society (ACS)
Year: 2019

description: The total reorganization energy, λ, for interfacial electron transfer, ET, from a conductive electrode to redox-active molecules at fixed positions within the electric double layer, EDL, has been determined experimentally. Conductive indium-tin-oxide (ITO, In2O3:Sn) mesoporous films were functionalized with 4-[N,N-di(p-tolyl)-amino]benzylphosphonic acid (TPA) and/or [RuII(bpy)2(4,4'-(PO3H2)2-bpy)]2+ (RuP), where bpy is 2,2'-bipyridine. The small inner-sphere reorganizations, λi, for RuIII/IIP and TPA+/0 make them excellent probes of outer-sphere reorganization energy, λo, as λin << λo such that λ = λin + λo ≈ λo. Consecutive layer-by-layer addition of ZrIV-bridged methylenediphosphonic acid enabled positioning at distances from 4 to 27 Å from the ITO. Excited-state injection into the ITO by RuP* generated ITO(e-)|RuIIIP. For ITO cofunctionalized with TPA and RuP, subnanosecond lateral ET yielded ITO(e-)|TPA+. The kinetics for ET from ITO to RuIIIP or TPA+ were quantified spectroscopically as a function of applied potential (Eapp) and hence driving force, -ΔG°. Marcus-Gerischer analysis of this data provided λ. Significantly, λo was near zero at close electrode proximity, λ = 0.11 eV at a distance of ~4 Å, as manifest by kinetics largely insensitive to Eapp. In agreement with dielectric continuum theory, λ increased to values expected in CH3CN solution when the molecule was positioned at a distance of ~27 Å (λ = 0.94 eV). The data reveal small intrinsic barriers for electron transfer proximate to conductive interfaces, which is an exploitable behavior in solar energy conversion and other applications that utilize transparent conductive oxides to accept or deliver electrons.
sj-pdf-1-ibe-10.1177_1420326X20944561 - Supplemental material for The impact of workspace location and indoor environmental quality on employees' satisfaction within office buildings: A case study in Cairo
Creators: name: Aboulfotouh, Ahmed Khaled
name: Tolba, Osama
name: Ezzeldin, Sherif
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental material, sj-pdf-1-ibe-10.1177_1420326X20944561 for The impact of workspace location and indoor environmental quality on employees' satisfaction within office buildings: A case study in Cairo by Ahmed Khaled Aboulfotouh, Osama Tolba and Sherif Ezzeldin in Indoor and Built Environment
sj-pdf-1-jir-10.1177_0022185620951830 - Supplemental material for The gendered consequences of skill-discounting for migrants
Creators: name: Treuren, Gerrit JM
name: Ashokkumar Manoharan
name: Vishnu, Vidya
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business

description: Supplemental material, sj-pdf-1-jir-10.1177_0022185620951830 for The gendered consequences of skill-discounting for migrants by Gerrit JM Treuren, Ashokkumar Manoharan and Vidya Vishnu in Journal of Industrial Relations
Electron-Promoted X-Type Ligand Displacement at CdSe Quantum Dot Surfaces
Creators: name: Dempsey, Jillian L.
name: Hartley, Carolyn L.
Publisher: name: American Chemical Society (ACS)
Year: 2019

description: Quantum dot surfaces are redox active and are known to influence the electronic properties of nanocrystals, yet the molecular-level changes in surface chemistry that occur upon addition of charge are not well understood. In this paper, we report a systematic study monitoring changes in surface coordination chemistry in 3.4 nm CdSe quantum dots upon remote chemical doping by the radical anion reductant sodium naphthalenide (Na[C10H8]). These studies reveal a new mechanism for charge-balancing the added electrons that localize on surface states through loss of up to ca. 5% of the native anionic carboxylate ligands, as quantified through a combination of UV-vis absorption, 1H NMR, and FTIR spectroscopies. A new method for distinguishing between reduction of surface metal and chalcogenide ions by monitoring ligand loss and optical changes upon doping is introduced. This work emphasizes the importance of studying changes in surface chemistry with remote chemical doping and is more broadly contextualized within the redox reactivity of the QD surface.
Emerging literature in the Microbiota-Brain Axis and Perinatal Mood and Anxiety Disorders
Creators: name: Williamson, Kelsey
name: Rackers, Hannah S.
name: Thomas, Stephanie
name: Posey, Rachael
name: Kimmel, Mary C.
Publisher: name: Elsevier
Year: 2018

description: Perinatal Mood and Anxiety Disorders (PMAD) are common and can cause significant morbidity and mortality for mother and child. A healthy perinatal period requires significant adaptations; however, systems can become imbalanced resulting in depressive and anxiety symptoms. The interface between the microbiome, the immune system, and the stress system may be a model for understanding mechanisms underlying PMAD. Emerging literature from general populations regarding immune, hormone, and HPA axis changes in relation to the microbiome combined with literature on immune, gonadotropin, and stress systems in the perinatal period provides a background. We systematically investigated literature in the developing field of the microbiome in relation to PMAD. Our inclusion criteria were 1) reporting measure of maternal mood, stress, or anxious or depressed behavior; 2) in the perinatal period, defined as pregnancy through one year postpartum; and 3) reporting measure of maternal microbiome including manipulations of the microbiome through prebiotics, probiotics, or interventions with microbial byproducts. The review identified research studying associations between stress and maternal microbiome; dietary impacts on microbial composition, mood, and stress; and the relationship between the microbiome and the immune system through immunoregulatory mechanisms. Important themes identified include: the importance of studying the maternal microbiome and measures of stress, anxiety, and depression and that multi-hit models will be needed as research strives to determine the effects of multiple mechanisms working in concert.
Supplemental Material, Supplement_Table_2 - Improvement of Neurological Function in Rats with Ischemic Stroke by Adipose-derived Pericytes
Creators: name: Ogay, Vyacheslav
name: Kumasheva, Venera
name: Li, Yelena
name: Mukhlis, Sholpan
name: Sekenova, Aliya
name: Farkhad Olzhayev
name: Tsoy, Andrey
name: Umbayev, Baurzhan
name: Askarova, Sholpan
name: Shpekov, Azat
name: Kaliyev, Assylbek
name: Zhetpisbayev, Berik
name: Makhambetov, Yerbol
name: Akshulakov, Serik
name: Saparov, Arman
name: Ramankulov, Yerlan
Publisher: name: SAGE Journals
Year: 2020
Subjects: Medicine
Cell Biology

description: Supplemental Material, Supplement_Table_2 for Improvement of Neurological Function in Rats with Ischemic Stroke by Adipose-derived Pericytes by Vyacheslav Ogay, Venera Kumasheva, Yelena Li, Sholpan Mukhlis, Aliya Sekenova, Farkhad Olzhayev, Andrey Tsoy, Baurzhan Umbayev, Sholpan Askarova, Azat Shpekov, Assylbek Kaliyev, Berik Zhetpisbayev, Yerbol Makhambetov, Serik Akshulakov, Arman Saparov and Yerlan Ramankulov in Cell Transplantation
Supplementary document for Dynamic Perturbation Mitigation via Polarization Difference Neural Network for High-Fidelity Ring Core Fiber Image Transmission - 7153920.pdf
Creators: name: WU, ZHEYU
name: Gao, Ran
name: Zhu, Jianping
name: Wang, Fei
name: Chang, Huan
name: li, zhipei
name: Guo, Dong
name: Zhu, Lei
name: Zhang, Qi
name: huang, Xin
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Detailed Description of Neural Network Architecture
Emerging roles of atypical chemokine receptor 3 (ACKR3) in normal development and physiology
Creators: name: Quinn, K.E.
name: Caron, K.M.
name: Mackie, D.I.
Publisher: name: Elsevier
Year: 2018

description: The discovery that atypical chemokine receptors (ACKRs) can initiate alternative signaling pathways rather than classical G-protein coupled receptor (GPCR) signaling has changed the paradigm of chemokine receptors and their roles in modulating chemotactic responses. The ACKR family has grown over the years, with discovery of new functions and roles in a variety of pathophysiological conditions. However, the extent to which these receptors regulate normal physiology is still continuously expanding. In particular, atypical chemokine receptor 3 (ACKR3) has proven to be an important receptor in mediating normal biological functions, including cardiac development and migration of cortical neurons. In this review, we illustrate the versatile and intriguing role of ACKR3 in physiology.
Ending Tribalism in Global Oncology
Creators: name: Gopal, Satish
Publisher: name: American Society of Clinical Oncology (ASCO)
Year: 2018

description: My recent experiences suggest there is broad consensus that global health is important and that this is a settled issue, despite seeming not so settled at times during the last year. Foremost among these experiences was the opportunity to participate in the Fogarty International Center 50th Anniversary Scientific Symposium on May 1, 2018, which showcased the remarkably broad political, academic, and civil society support enjoyed by the center. It also highlighted the amazing constellation of human capacity building, health systems strengthening, and scientific achievements it has engendered around the world in its first 50 years through small, strategic, catalytic investments. Within my own global oncology discipline, a similar broad consensus—namely, that global health matters—has been demonstrated by recent advisory group discussions at the US National Cancer Institute regarding its substantial global health portfolio, the convening by ASCO of an Academic Global Oncology Stakeholders Summit, and a dedicated session highlighting cancer as a global issue at the annual meeting of the Association of American Cancer Institutes. I have been fortunate enough to be invited to participate in all of these gatherings.
Madymik star men Adyayanrat Vidhyarthiyon ki Samajik Budhi ka Jansankhyikeeya aadhar par Adyayan
Creators: name: Chauhan, Ramesh Singh
Publisher: name: figshare
Year: 2022
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology

description: Intelligence has an important role in the personality development of a child. Intelligence is a boon received from God to human being. It is because of Intelligence that man is considered the best creature. Intelligence is an innate mental ability which helps individual to understand various conditions and make changes in his behavior accordingly. One is able to solve problems and achieve success in his behavioural life with the help of Intelligence. Various philosophers, sociologists and scholars have studied sociability & social behaviour and interpersonal relationships according to their intelligence and have propounded various views and constructed different dimensions, methods and theories. It is on the basis of Intelligence, that a man develops the ability of reasoning and decision making which help him to understand the desired and undesired behaviour, which a man requires every moment being surrounded by society. Every now and then he is completing his one or other relationship at every place. That is why famous sociologist Mcigber has said "society is a network of social relationships." Hence, to fulfill the social needs of a society, the social Intelligence of a man plays a very important and compulsory part. In present times, revolution in information technoligy has widened the communication skills. Management,, commerce, Politics, service or specialized areas has posed challenges on a bigger scale for social skills and abilities of an individual. Keeping all these facts in mind, it is significant to study the social Intelligence of an individual deeply so that the learner becomes well adapted in different vocations and services in the course of time and is capable to carry on his social responsibility properly. …
Endothelial cell SMAD6 balances ACVRL1/Alk1 function to regulate adherens junctions and hepatic vascular development
Creators: name: Oatley, Morgan
name: Kulikauskas, Molly R.
name: Liu, Ziqing
name: Kidder, Elise
name: Yu, Tianji
name: Bautch, Victoria L.
name: Matsumura, Lauren
name: Ruter, Dana
Publisher: name: The Company of Biologists
Year: 2023

description: BMP signaling is crucial to blood vessel formation and function, but how pathway components regulate vascular development is not well-understood. Here, we find that inhibitory SMAD6 functions in endothelial cells to negatively regulate ALK1-mediated responses, and it is required to prevent vessel dysmorphogenesis and hemorrhage in the embryonic liver vasculature. Reduced Alk1 gene dosage rescued embryonic hepatic hemorrhage and microvascular capillarization induced by Smad6 deletion in endothelial cells in vivo. At the cellular level, co-depletion of Smad6 and Alk1 rescued the destabilized junctions and impaired barrier function of endothelial cells depleted for SMAD6 alone. Mechanistically, blockade of actomyosin contractility or increased PI3K signaling rescued endothelial junction defects induced by SMAD6 loss. Thus, SMAD6 normally modulates ALK1 function in endothelial cells to regulate PI3K signaling and contractility, and SMAD6 loss increases signaling through ALK1 that disrupts endothelial cell junctions. ALK1 loss-of-function also disrupts vascular development and function, indicating that balanced ALK1 signaling is crucial for proper vascular development and identifying ALK1 as a 'Goldilocks' pathway in vascular biology that requires a certain signaling amplitude, regulated by SMAD6, to function properly.
Enhancing scanning electrochemical microscopy's potential to probe dynamic co-culture systems via hyperspectral assisted-imaging
Creators: name: Goines, Sondrica
name: Leung, Justin W C
name: Glasscott, Matthew W
name: Dick, Jeffrey E
name: Deng, Mingchu
Publisher: name: Royal Society of Chemistry (RSC)
Year: 2022

description: Precise determination of boundaries in co-culture systems is difficult to achieve with scanning electrochemical microscopy alone. Thus, biological scanning electrochemical microscope platforms generally consist of a scanning electrochemical microscope positioner mounted on the stage of an inverted microscope for correlated electrochemical and optical imaging. Use of a fluorescence microscope allows for site-specific fluorescence labeling to obtain more clearly resolved spatial and electrochemical data. Here, we construct a unique hyperspectral assisted-biological scanning electrochemical microscope platform to widen the scope of biological imaging. Specifically, we incorporate a variable fluorescence bandpass source into a biological scanning electrochemical microscope platform for simultaneous optical, spectral, and electrochemical imaging. Not only does this platform serve as a cost-effective alternative to white light laser imaging, but additionally it provides multi-functional analysis of biological samples. Here, we demonstrate the efficacy of our platform to discern the electrochemical contribution of site-specific cells by optically and spectroscopically resolving boundaries as well as cell types within a complex biological system.
Table_S1 – Supplemental material for Evolutionary Analysis of Makorin Ring Finger Protein 3 Reveals Positive Selection in Mammals
Creators: name: Ahmad, Muhammad Jamil
name: Ahmad, Hafiz Ishfaq
name: Adeel, Muhammad Muzammal
name: Aixin Liang
name: Guohua Hua
name: Murtaza, Saeed
name: Mirza, Riaz Hussain
name: Abdelmotaleb Elokil
name: Ullah, Farman
name: Liguo Yang
Publisher: name: SAGE Journals
Year: 2019
Subjects: Cell Biology

description: Supplemental material, Table_S1 for Evolutionary Analysis of Makorin Ring Finger Protein 3 Reveals Positive Selection in Mammals by Muhammad Jamil Ahmad, Hafiz Ishfaq Ahmad, Muhammad Muzammal Adeel, Aixin Liang, Hua Guohua, Saeed Murtaza, Riaz Hussain Mirza, Abdelmotaleb Elokil, Farman Ullah and Liguo Yang in Evolutionary Bioinformatics
Enriched Marine Oil Supplement Increases Specific Plasma Specialized Pro-Resolving Mediators in Adults with Obesity
Creators: name: Tharwani, Sonum
name: Maddipati, Krishna Rao
name: Butler, Erik
name: Drawdy, Catie
name: Kane, Shawn
name: Behee, Madeline
name: Fenton, Jenifer I
name: Sergin, Selin
name: Shaikh, Saame Raza
name: Regan, Jennifer
name: Al-Shaer, Abrar E
name: Buddenbaum, Nicole
Publisher: name: Elsevier
Year: 2022

description: BACKGROUND: Specialized pro-resolving mediators (SPMs), synthesized from PUFAs, resolve inflammation and return damaged tissue to homeostasis. Thus, increasing metabolites of the SPM biosynthetic pathway may have potential health benefits for select clinical populations, such as subjects with obesity who display dysregulation of SPM metabolism. However, the concentrations of SPMs and their metabolic intermediates in humans with obesity remains unclear. OBJECTIVES: The primary objective of this study was to determine if a marine oil supplement increased specific metabolites of the SPM biosynthetic pathway in adults with obesity. The second objective was to determine if the supplement changed the relative abundance of key immune cell populations. Finally, given the critical role of antibodies in inflammation, we determined if ex vivo CD19 + B-cell antibody production was modified by marine oil intervention. METHODS: Twenty-three subjects [median age: 56 y; BMI (in kg/m2): 33.1] consumed 2 g/d of a marine oil supplement for 28-30 d. The supplement was particularly enriched with 18-hydroxyeicosapentaenoic (HEPE), 14-hydroxydocosahexaenoic acid (14-HDHA), and 17-HDHA. Blood was collected pre- and postsupplementation for plasma mass spectrometry oxylipin and fatty acid analyses, flow cytometry, and B-cell isolation. Paired t-tests and Wilcoxon tests were used for statistical analyses. RESULTS: Relative to preintervention, the supplement increased 6 different HEPEs and HDHAs accompanied by changes in plasma PUFAs. Resolvin E1 and docosapentaenoic acid-derived maresin 1 concentrations were increased 3.5- and 4.7-fold upon intervention, respectively. The supplement did not increase the concentration of D-series resolvins and had no effect on the abundance of immune cells. Ex vivo B-cell IgG but not IgM concentrations were lowered postsupplementation. CONCLUSIONS: A marine oil supplement increased select SPMs and their metabolic intermediates in adults with obesity. Additional studies are needed to determine if increased concentrations of specific SPMs control the resolution of inflammation in humans with obesity. This trial was registered at clinicaltrials.gov as NCT04701138.
Surface-modified cationic liposomes with a matrix metalloproteinase-degradable polyethylene glycol derivative improved doxorubicin delivery in murine colon cancer
Creators: name: Askarizadeh, Anis
name: Mashreghi, Mohammad
name: Mirhadi, Elaheh
name: Mehrabian, Amin
name: Shargh, Vahid Heravi
name: Badiee, Ali
name: Alavizadeh, Seyedeh Hoda
name: Arabi, Leila
name: Kamali, Hossein
name: Jaafari, Mahmoud Reza
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: PEGylation is a commonly used approach to prolong the blood circulation time of cationic liposomes. However, PEGylation is associated with the "PEG dilemma", which hinders binding and uptake into tumor cells. The cleavable PEG products are a possible solution to this problem. In the current research, doxorubicin-loaded cationic liposomes (Dox-CLs) surface-conjugated with a matrix metalloproteinase-2 (MMP-2)-sensitive octapeptide linker-PEG derivative were prepared and compared to non-PEGylated and PEGylated CLs in terms of size, surface charge, drug encapsulation and release, uptake, in vivo pharmacokinetics, and anticancer efficacy. It was postulated that PEG deshielding in response to the overexpressed MMP-2 in the tumor microenvironment increases the interaction of protected CLs with cellular membranes and improves their uptake by tumor cells/vasculature. MMP2-responsive Dox-CLs had particle sizes of ∼115-140 nm, surface charges of ∼+25 mV, and encapsulation efficiencies of ∼85-95%. In vitro cytotoxicity assessments showed significantly enhanced uptake and cytotoxicity of PEG-cleavable CLs compared to their non-cleavable PEG-coated counterparts or Caelyx®. Also, the chick chorioallantoic membrane assay showed great antiangiogenesis ability of Dox-CLs leading to target and prevent tumor neovascularization. Besides, in vivo studies showed an effective therapeutic efficacy of PEG-cleavable Dox-CLs in murine colorectal cancer with negligible hematological and histopathological toxicity. Altogether, our results showed that MMP2-responsive Dox-CLs could be served as a promising approach to improve tumor drug delivery and uptake.
Supplementary document for INTERFERE, Short-Time Fourier Transform based compression of complex-valued holograms with bit-depth and range-adaptive quantization - 7154165.pdf
Creators: name: Muhamad, Raees Kizhakkumkara
name: Birnbaum, Tobias
name: Blinder, David
name: Schelkens, Peter
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: RDO description and additional validation
Estimating Individualized Treatment Rules for Ordinal Treatments
Creators: name: Liu, Yufeng
name: He, Xuanyao
name: Chen, Jingxiang
name: Kosorok, Michael R.
name: Fu, Haoda
Publisher: name: Oxford University Press (OUP)
Year: 2018

description: Precision medicine is an emerging scientific topic for disease treatment and prevention that takes into account individual patient characteristics. It is an important direction for clinical research, and many statistical methods have been proposed recently. One of the primary goals of precision medicine is to obtain an optimal individual treatment rule (ITR), which can help make decisions on treatment selection according to each patient's specific characteristics. Recently, outcome weighted learning (OWL) has been proposed to estimate such an optimal ITR in a binary treatment setting by maximizing the expected clinical outcome. However, for ordinal treatment settings, such as individualized dose finding, it is unclear how to use OWL. In this article, we propose a new technique for estimating ITR with ordinal treatments. In particular, we propose a data duplication technique with a piecewise convex loss function. We establish Fisher consistency for the resulting estimated ITR under certain conditions, and obtain the convergence and risk bound properties. Simulated examples and an application to a dataset from a type 2 diabetes mellitus observational study demonstrate the highly competitive performance of the proposed method compared to existing alternatives.
Ethanol-induced conditioned place preference and aversion differentially alter plasticity in the bed nucleus of stria terminalis
Creators: name: Kash, Thomas L.
name: Pati, Dipanwita
name: Pina, Melanie M.
Publisher: name: Springer Nature
Year: 2019

description: Contextual cues associated with drugs of abuse, such as ethanol, can trigger craving and drug-seeking behavior. Pavlovian procedures, such as place conditioning, have been widely used to study the rewarding/aversive properties of drugs and the association between environmental cues and drug seeking. Previous research has shown that ethanol as an unconditioned stimulus can induce a strong conditioned place preference (CPP) or aversion (CPA) in rodents. However, the neural mechanisms underlying ethanol-induced reward and aversion have not been thoroughly investigated. The bed nucleus of the stria terminalis (BNST), an integral part of the extended amygdala, is engaged by both rewarding and aversive stimuli and plays a role in ethanol-seeking behavior. Here, we used ex-vivo slice physiology to probe learning-induced synaptic plasticity in the BNST following ethanol-induced CPP and CPA. Male DBA/2J mice (2-3 months old) were conditioned using previously reported ethanol-induced CPP/CPA procedures. Ethanol-induced CPP was associated with increased neuronal excitability in the ventral BNST (vBNST). Conversely, ethanol-induced CPA resulted in a significant decrease in spontaneous glutamatergic transmission without alterations in GABAergic signaling. Ethanol-CPA also led to a significant increase in the paired-pulse ratio at excitatory synapses, suggestive of a decrease in presynaptic glutamate release. Collectively, these data demonstrate that the vBNST is involved in the modulation of contextual learning associated with both the rewarding and the aversive properties of ethanol in mice.
Evaluating the geomorphic channel response to beaver dam analog installation using unoccupied aerial vehicles
Creators: name: Pearce, Casey
name: Davis, Julianne
name: Lautz, Laura
name: Kelleher, Christa
name: Vidon, Philippe
name: Russoniello, Christopher
Publisher: name: Wiley
Year: 2021

description: Abstract Beaver dam analogs (BDAs) are a stream restoration technique that is rapidly gaining popularity in the western United States. These low-cost, stream-spanning structures, designed after natural beaver dams, are being installed to confer the ecologic, hydrologic, and geomorphic benefits of beaver dams in streams that are often too degraded to provide suitable beaver habitat. BDAs are intended to slow streamflow, reduce the erosive power of the stream, and promote aggradation, making them attractive restoration tools in incised channels. Despite increasing adoption of BDAs, few studies to date have monitored the impacts of BDAs on channel form. Here, we examine the geomorphic changes that occurred within the first year of restoration efforts in Wyoming using high-resolution visible light orthomosaics and elevation data collected with unoccupied aerial vehicles (UAVs). By leveraging the advantages of rapidly acquired images from UAV surveys with recent advancements in structure-from-motion photogrammetry, we constructed centimeter-scale digital elevation models (DEMs) of the restoration reach and an upstream control reach. Through DEM differencing, we identified areas of enhanced erosion and deposition near the BDAs, suggesting BDA installation initiated a unique geomorphic response in the channel. Both reaches were characterized by net erosion during the first year of restoration efforts. While erosion around the BDAs may seem counter to the long-term goal of BDA-induced aggradation, short-term net erosion is consistent with high precipitation during the study and with theoretical channel evolution models of beaver-related stream restoration that predict initial channel widening and erosion before net deposition. To better understand the impacts of BDAs on channel morphology and restoration efforts in the western United States, it is imperative that we consistently assess the effects of beaver-inspired restoration projects across a range of hydrologic and geomorphic settings and that we continue this monitoring in the future.