cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Vertical Model Integration in Frameworks - Evaluation of Integration Approaches and Investigation of the Feasibility of Implementing a Case Study
Creators: name: Bögel, Stephan
name: Esswein, Werner
Publisher: name: Gesellschaft für Informatik e.V. (The German Informatics Society)
Year: 2015

description: The model driven simulation of mobile construction equipment is investigated in the BMBF-funded project INPROVY. A framework was introduced to structure the problem and divide it into different model layers. The vertical integration of the different model layers is the subject of this article. An evaluation through the method of feature-based comparisons of the integration approaches that represent the state of research is carried out. In a small case-study the applicability of vertical model integration in the field of model driven simulation is analysed.
description: Enterprise Modelling and Information Systems Architectures, Vol 6, No 3 (2011)
Axiomatizing modal inclusion logic and its variants
Creators: name: Anttila, Aleksi
name: Häggblom, Matilda
name: Yang, Fan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics
subject: 03B60

description: We provide a complete axiomatization of modal inclusion logic - team-based modal logic extended with inclusion atoms. We review and refine an expressive completeness and normal form theorem for the logic, define a natural deduction proof system, and use the normal form to prove completeness of the axiomatization. Complete axiomatizations are also provided for two other extensions of modal logic with the same expressive power as modal inclusion logic: one augmented with a might operator and the other with a single-world variant of the might operator.
description: 38 pages
title: A Child's Guide to Energy Intensity and Energy Efficiency
Creators: name: Figus, Gioele
name: Swales, Kim
Publisher: name: University of Strathclyde
Year: 2022

description: This paper focusses on ambiguities in the discussion of energy efficiency linked to the fact that energy is typically combined with other non-energy inputs to generate energy-using services. An important potential source of misunderstanding concerns the different measures of energy efficiency. We draw here a clear distinction between energy effectiveness (also known as energy augmenting technical change) and energy intensity. In this discussion we stress the importance of various forms of endogenous substitution in determining changes in energy intensity following improvements in energy effectiveness. We also analyse the potential impact on energy intensity of improvements in the effectiveness of non-energy inputs. Finally, we explore the treatment of the costs of activating energy saving technology embodied in capital equipment.
Device independent security of quantum key distribution from monogamy-of-entanglement games
Creators: name: Cervero-Martín, Enrique
name: Tomamichel, Marco
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We analyse two party non-local games whose predicate requires Alice and Bob to generate matching bits, and their three party extensions where a third player receives all inputs and is required to output a bit that matches that of the original players. We propose a general device independent quantum key distribution protocol for the subset of such non-local games that satisfy a monogamy-of-entanglement property characterised by a gap in the maximum winning probability between the bipartite and tripartite versions of the game. This gap is due to the optimal strategy for two players requiring entanglement, which due to its monogamy property cannot be shared with any additional players. Based solely on the monogamy-of-entanglement property, we provide a simple proof of information theoretic security of our protocol. Lastly, we numerically optimize the finite and asymptotic secret key rates of our protocol using the magic square game as an example, for which we provide a numerical bound on the maximal tripartite quantum winning probability which closely matches the bipartite classical winning probability. Further, we show that our protocol is robust for depolarizing noise up to about $2.2\%$, providing the first such bound for general attacks for magic square based quantum key distribution.
description: 42 pages, 7 figures, 2 tables
Strategic Productivity Management in Small and Medium-Sized Service Enterprises Using the Service Navigator
Creators: name: Borchert, Margret
name: Klinkhammer, Stefanie
name: Koch, Eva
Publisher: name: Gesellschaft für Informatik e.V. (The German Informatics Society)
Year: 2015

description: Service productivity has become a widely accepted issue in science and practice. But so far there are no holistic and widely accepted methods for systematic productivity management for services, especially for small and medium-sized enterprises (SMEs). Not only quantitative measures play an important role (e.g., financial measures) but also qualitative measures such as service quality or customer satisfaction have to be considered. Furthermore, the incorporation of service and SME specific characteristics has not been effective. In addition, a relationship between performance and productivity management has not been established. Closing this gap requires redefining the concept of service productivity and positioning it in relation to performance measurement. Against this background, the present article aims at presenting the conception and development of a holistic service productivity instrument, the Service Navigator. This instrument is based on a revised definition of strategic productivity that takes the dynamic character of the cause-and-effect relationships between strategic and operative measures into account. The Service Navigator is intended to enable SMEs to measure, assess and control the cause-and-effect relationships among inputs, sub-processes and outputs that are relevant for productivity. Subsequently the results of an explorative qualitative-empirical study on the development of the Service Navigator are presented and finally an outlook on further needs for research is given.
description: Enterprise Modelling and Information Systems Architectures, Vol 7, No 1 (2012)
Construction of Productivity Models - A Tool-Supported Approach in the Area of Facility Management
Creators: name: Becker, Jörg
name: Bernhold, Torben
name: Beverungen, Daniel
name: Kaling, Nina
name: Knackstedt, Ralf
name: Lellek, Vanessa
name: Rauer, Hans Peter
Publisher: name: Gesellschaft für Informatik e.V. (The German Informatics Society)
Year: 2015

description: Productivity models specify input and output factors to inform productivity analyses. Current research and business practice face the challenge of developing a wide range of different productivity models. These models were created simultaneously but isolated from each other. As a consequence thereof, several practices of productivity model construction have emerged. This paper presents a unifying modelling language that lists and interrelates the essential constructs, pertinent to productivity models. Ultimately it was transferred into practice by employing a software tool. The application was conducted in the area of facility management, supporting two different approaches of productivity benchmarking. Facility management features a huge diversity of offered services and bundles. Thus, facility managers cope with various definitions of productivity that are then modelled with our approach.
description: Enterprise Modelling and Information Systems Architectures, Vol 7, No 1 (2012)
Formal Modelling of Components and Dependencies for Configuring Product-Service-Systems
Creators: name: Klingner, Stephan
name: Becker, Michael
Publisher: name: Gesellschaft für Informatik e.V. (The German Informatics Society)
Year: 2015

description: The increasing entwinement of products and services in combined offers – so called Product-Service Systems (PSS) – leads to various requirements regarding the modelling of those systems. Due to these requirements, software support is needed for customer-specific configuration of complex PSS. To provide such software a formal description of the structure of products and services is required. Furthermore, complex logical interdependencies between products and services need to be described. Based on an existing service modelling notation the following paper develops a holistic notation for PSS. To describe the interdependencies within PSS, dependency rules are formally specified.
description: Enterprise Modelling and Information Systems Architectures, Vol 7, No 1 (2012)
Usos y potencialidades de la Inteligencia Artificial Generativa en el proceso de enseñanza y aprendizaje
Creators: name: Pozo Sánchez, Santiago
Publisher: name: Zenodo
Year: 2024

description:  

En esta presentación exploraremos los conceptos fundamentales de la inteligencia artificial generativa y su potencial para transformar la educación. Analizaremos sus beneficios, especialmente en áreas como la personalización del aprendizaje, la promoción de la creatividad y el aumento de la accesibilidad. Además, evaluaremos los riesgos y desafíos que plantea, abordando temas de ética, privacidad y sesgos. Finalmente, descubriremos aplicaciones prácticas de la IA generativa en el ámbito educativo y nos adentraremos en las últimas tendencias y novedades para mantenernos actualizados en esta área en constante evolución.
An Actor-Oriented Model of a Service Provision
Creators: name: Tackenberg, Sven
name: Duckwitz, Sönke
name: Schlick, Christopher M.
Publisher: name: Gesellschaft für Informatik e.V. (The German Informatics Society)
Year: 2015

description: The development of valid and efficient plans for service provision is a critical success factor for companies. Adequate planning assures the optimal use of resources, customer satisfaction, and the attainment of service targets in an acceptable period of time. Where these plans are incorrect or provide only a small contribution to the objectives of the company, resources are wasted and opportunities are missed. The problem of planning an efficient service provision can be described in the form of tasks that must be scheduled subject to precedence and resource constraints. Consequently, an analysis of existing scheduling models from the perspective of service providers is necessary to use them in the field of service management. The purpose of this paper is to provide a formal description of an actor-oriented model of a service provision that can be used for person-centered simulation. Such a model defines the decision variables and constraints to be determined by a person or a software tool during service management. Finally, we provide insight into the use of a formal model in case of a simulation study.
description: Enterprise Modelling and Information Systems Architectures, Vol 7, No 1 (2012)
Teoria Una Particella  Due Punti dello Spazio Tempo La Funzione d'Onda come Pura Energia
Creators: name: Mercadante, Giovanni
Publisher: name: Zenodo
Year: 2025
Subjects: • Quantum wave function as energy
• Quantum mechanics and spacetime structure
• Wave function collapse as energy localization
• Emergent time from quantum energy fields
• Quantum decoherence and material solidity
• Fundamental energy field and universe structure
• Quantum physics and the illusion of solidity
• Quantum perception of time and matter

description: Questa pubblicazione esplora una nuova interpretazione della funzione d’onda quantistica, basandosi sulla teoria "Una particella e due punti dello spaziotempo".Si propone che la funzione d’onda non sia solo una descrizione della probabilità, ma la forma più fondamentale dell’energia nell’universo.Da questa visione emergono nuove implicazioni per il tempo, la materia e la struttura stessa della realtà.
rexposome: a bioinformatic tool for characterizing multiple environmental factors and its association with different omics biomarkers and disease
Creators: name: Hernandez, Carles
name: Vrijheid, Martine
name: Gonzalez, Juan R.
Publisher: name: F1000Research
Year: 2016

description: Exposome encompasses all environmental factors from conception until old age. The HELIX 'early-life exposome' approach involves combining all environmental hazards that mothers and children are exposed to, and linking this to the health, growth and development of the children. The main objectives of HELIX project include the measurement of a wide range of chemicals and physical environmental hazards in food, consumer products, water, air, noise, and the build environment. Also to define multi-pattern and individual exposure variability while determining a molecular profile and biological pathways associated with those multiple exposures.

We developed a Bioconductor package (rexposome) to address HELIX's goals. The package incorporates functions for exploring exposome and its interaction with outcomes, its integration with different omic data as well as downstream analyses to facilitate biological insights though pathway analyses and GO terms. In this talk, the package will be introduced. Package performace will be illustrated by analyzing a subset of the HELIX’s Spanish cohort that includes 88 exposures (grouped into 13 families), methylation and gene expression data for 657 subjects. Single association analyses found that three BDEs (Polybrominated diphenyl ethers) were associated with cell development, cell differentiation, neurogenesis and axon development. Our results also reveal associations betweeen Pb (Metal) and DDT (Organochlorine) with multiple RNA regulation and metabolic processes, respectively. Our multi-omic analysis found a significant asoociation between genes RP11, RNU6 and HTR3E with particle matter.
Retrotransverse foramen in atlas vertebrae of the late 17th and 18th centuries
Creators: name: Quiles-Guiñau, Laura
name: Gómez-Cabrero, Azucena
name: Miquel-Feucht, Marcos
name: Aparicio-Bellver, Luís
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2016
Subjects: cervical atlas; anatomical variation; transverse foramen; Spain

description: Anatomical variations of the atlas vertebra are of particular importance because of their possible repercussions on the vertebral vessels. In view of the extensive articular mobility of the atlas, any anomaly where the vertebral artery and veins run through the transverse foramen could impair blood flow. However, in spite of the possible effect of this anomaly on the vertebral artery and veins, there are few data on the presence of an abnormal accessory transverse foramen, termed retrotransverse foramen, which is smaller and located behind the transverse foramen of the atlas. The aim of this research was to analyse the prevalence of retrotransverse foramen in a sample of 88 dry C1 vertebrae from a Spanish rural population of the late 17th and the early 18th centuries, as well as to study the possible repercussions of the presence of this anatomical variant on the size of the transverse foramen. The anteroposterior diameter and the lateral diameter of the transverse foramen of all the atlas vertebrae and retrotransverse foramina were measured using digital calibres. Two atlases with retrotransverse foramina (2.27%) were found in which the presence of the anatomical variant caused a larger anteroposterior diameter and a smaller lateral diameter than those of the transverse foramina of the normal 86 C1 vertebrae that were analysed. Our results show that a thorough study should be performed on the prevalence of this anatomical variant in the current population, as well as its possible clinical repercussion on the vertebral artery.
description: Italian Journal of Anatomy and Embryology, Vol 121, No 2 (2016)
MRI bias field correction with an implicitly trained CNN - Trained model and minimal example
Creators: name: Attila, Simkó
Publisher: name: Zenodo
Year: 2021
Subjects: Magnetic resonance imaging
bias field correction
medical image analysis
machine learning
convolutional neural network
implicit training

description: A software documentation for the paper "MRI bias field correction with an implicitly trained CNN". The code is available at: https://github.com/attilasimko/bfc The primary purpose of the repository is to publish the trained model, which is contained in the "implicit.zip" file as a standalone model called "implicit.pb". The repository also contains "MICE_example.ice" which is an example in MICE Toolkit where the implicit.pb model is compared to N4ITK using the dataset contained in data.zip, which was generated from BrainWeb (https://brainweb.bic.mni.mcgill.ca/).
title: Mechanically-tunable bandgap closing in 2D graphene phononic crystals
Creators: name: Kirchhof, Jan N.
name: Bolotin, Kirill
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Acoustics
subject: Condensed-matter physics
subject: Nanoscience and technology
classificationCode: 530
subject: Physik

description: We present a tunable phononic crystal which can be switched from a mechanically insulating to a mechanically conductive (transmissive) state. Specifically, in our simulations for a phononic lattice under biaxial tension (σxx = σyy = 0.01 N m−1), we find a bandgap for out-of-plane phonons in the range of 48.8–56.4 MHz, which we can close by increasing the degree of tension uniaxiality (σxx/σyy) to 1.7. To manipulate the tension distribution, we design a realistic device of finite size, where σxx/σyy is tuned by applying a gate voltage to a phononic crystal made from suspended graphene. We show that the bandgap closing can be probed via acoustic transmission measurements and that the phononic bandgap persists even after the inclusion of surface contaminants and random tension variations present in realistic devices. The proposed system acts as a transistor for MHz-phonons with an on/off ratio of 105 (100 dB suppression) and is thus a valuable extension for phonon logic applications. In addition, the transition from conductive to isolating can be seen as a mechanical analogue to a metal-insulator transition and allows tunable coupling between mechanical entities (e.g. mechanical qubits).
MPEC 2024-V104 : DAILY ORBIT UPDATE (2024 November 8)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
A Randomized Controlled Trial of a Hot Spots Policing Initiative in Suburban and Rural Areas
Creators: name: Haberman, Cory P.
name: O’Guinn, Bradley J.
name: McGrath, Matthew
name: Kumavat, Akshata V.
name: Orue, Augusto
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: This paper overviews the Hamilton County (OH) Sheriff’s Office (HCSO) Smart Policing Initiative (SPI). The HCSO SPI was designed to address repeat call for service (CFS) hot spots using a holistic strategy. A matched pair randomized controlled trial evaluation of 13 treatment hot spots and 13 control hot spots was performed. Directed patrols documented via CAD, line-level supervisors’ implementation reports, and interviews with 5 key informants suggested implementation fidelity varied across sites. For implementation Year 1, crime-related CFS were down about 23% (991 to 759) in the 13 treatment hot spots compared the year before implementation started relative to a 16% (740 to 619) reduction in the 13 control hot spots. For implementation Year 2, crime-related CFS were down by about 28% (991 to 710) in the 13 treatment hot spots compared the year before implementation started relative to about a 17% (740 to 616) reduction in the 13 control hot spots. Paired samples t-tests suggest only the Year 2 change was statistically significant at the p < 0.10 level. The hot spots with the greatest and most consistent reductions in calls for service were those with the most treatment fidelity. The results are discussed in context of the hot spots policing literature as well as practitioner insights on organizational change and lessons learned for agencies with similar operational contexts seeking implement hot spots policing initiatives in the future.
Vegane Ernährung als Klimaretter und Gesundheitsbooster
Creators: name: Loretz Nicolas, Trüb Moira
Publisher: name: Zenodo
Year: 2022
Subjects: Vegan
nutrition
Sustainable Development Goals
Food
Beverage
Health

description: Ein Paper, das die heilsamen Effekte der veganen Ernährung für den Menschen sowohl auf die Gesundheit als auch auf das Klima thematisiert.
Construction of smooth isomorphic and finite-to-one extensions of irrational rotations which are not almost automorphic
Creators: name: Haupt, Lino
name: Jäger, Tobias
Publisher: name: arXiv
Year: 2023
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37B05, 37C05

description: Due to a result by Glasner and Downarowicz, it is known that a minimal system is mean equicontinuous if and only if it is an isomorphic extension of its maximal equicontinuous factor. The majority of known examples of this type are almost automorphic, that is, the factor map to the maximal equicontinuous factor is almost one-to-one. The only cases of isomorphic extensions which are not almost automorphic are again due to Glasner and Downarowicz, who in the same article provide a construction of such systems in a rather general topological setting.
 Here, we use the Anosov-Katok method in order to provide an alternative route to such examples and to show that these may be realised as smooth skew product diffeomorphisms of the two-torus with an irrational rotation on the base. Moreover - and more importantly - a modification of the construction allows to ensure that lifts of these diffeomorphism to finite covering spaces provide novel examples of finite-to-one topomorphic extensions of irrational rotations. These are still strictly ergodic and share the same dynamical eigenvalues as the original system, but show an additional singular continuous component of the dynamical spectrum.
Risk factors for prosthetic joint infections following total hip arthroplasty based on 33,337 hips in the Finnish Arthroplasty Register from 2014 to 2018
Creators: name: Panula, Valtteri J
name: Alakylä, Kasperi J
name: Venäläinen, Mikko S
name: Haapakoski, Jaason J
name: Eskelinen, Antti P
name: Manninen, Mikko J
name: Kettunen, Jukka S
name: Puhto, Ari-Pekka
name: Vasara, Anna I
name: Elo, Laura L
name: Mäkelä, Keijo T
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Background and purpose — Periprosthetic joint infection (PJI) is a devastating complication and more information on risk factors for PJI is required to find measures to prevent infections. Therefore, we assessed risk factors for PJI after primary total hip arthroplasty (THA) in a large patient cohort. Patients and methods — We analyzed 33,337 primary THAs performed between May 2014 and January 2018 based on the Finnish Arthroplasty Register (FAR). Cox proportional hazards regression was used to estimate hazard ratios with 95% confidence intervals (CI) for first PJI revision operation using 25 potential patient- and surgical-related risk factors as covariates. Results — 350 primary THAs were revised for the first time due to PJI during the study period. The hazard ratios for PJI revision in multivariable analysis were 2.0 (CI 1.3–3.2) for ASA class II and 3.2 (2.0–5.1) for ASA class III–IV compared with ASA class I, 1.4 (1.1–1.7) for bleeding > 500 mL compared with < 500 mL, 0.4 (0.2–0.7) for ceramic-on-ceramic bearing couple compared with metal-on-polyethylene and for the first 3 postoperative weeks, 3.0 (1.6–5.6) for operation time of > 120 minutes compared with 45–59 minutes, and 2.6 (1.4–4.9) for simultaneous bilateral operation. In the univariable analysis, hazard ratios for PJI revision were 2.3 (1.7–3.3) for BMI of 31–35 and 5.0 (3.5–7.1) for BMI of > 35 compared with patients with BMI of 21–25. Interpretation — We found several modifiable risk factors associated with increased PJI revision risk after THA to which special attention should be paid preoperatively. In particular, high BMI may be an even more prominent risk factor for PJI than previously assessed.
High-efficiency differentiation into functional dopaminergic neurons from Parkinson’s patients-derived induced pluripotent stem cells
Creators: name: Schuele, Birgitt
name: Zafar, Faria
name: Soojung Shin
name: Derr Michael
name: Nguyen, Andrew
name: Flierl, Adrian
Publisher: name: F1000Research
Year: 2016

description: The objective of the study was to compare two neuronal differentiation protocols, Pluripotent Stem Cell (PSC) Dopaminergic (DA) Neuron Differentiation Kit (Prototype, Thermo Fisher, catalog Number

A30416SA) and our dopaminergic differentiation protocol (Mak et al. 2012) for length of protocol, efficiency of DA neuron generation, and electrophysiological properties.

Parkinson disease (PD) patient specific induced PSCs (iPSC) differentiated into DA neurons lay the foundation for exploring disease mechanism and drug discovery. However, there remain critical challenges that must be addressed to reduce variability. It is important to develop standardized and validated iPS cell laboratory practices to generate and characterize cells. Critical factors for successful neuronal differentiation are yield of desired, functional target tissue type, reproducibility of the protocol, duration of differentiation, and cost.

We tested two different protocols to achieve high yield of DA neurons using iPSCs from PD patients. Two approaches were 1. embryoid body (EB)/rosette derived neural stem cells induced with dual SMAD inhibition and NCAM sorting that are further differentiated into mature neurons (via GDNF/BDNF) (Mak et al. 2012) in ~60 days and 2. direct differentiation of iPSCs through floorplate progenitor into mature DA neurons via PSC Dopaminergic Neuron Differentiation Kit in 35 days.

Higher amount of DA neuron specific enzyme, tyrosine hydroxylase, were obtained after 35 days of differentiation with the PSC Dopaminergic Neuron Differentiation Kit compared to cells derived with EB/dual SMAD inhibition protocol after 60 days. The PSC Dopaminergic Neuron Differentiation Kit showed a sharp increase in floorplate/mesencephalic markers such as FOXA2, Corin, LMX1A, and EN-1 at Day 10 (expression range of 10-10,000 fold increase in comparison to day 0). Neuronal cultures showed spontaneous activity on multielectrode arrays (MEA, Axion Biosystems) of about 3000 spikes and an average amplitude of 22µV(range of 17µV to 40µV).

In summary, dopaminergic differentiation with the ThermoFisher PSC Dopaminergic Neuron Differentiation Kit provided reproducible culture conditions, shorter differentiation time, and a high-yield of functional dopaminergic neurons.
No increased mortality after total hip arthroplasty in patients with a history of pediatric hip disease: a matched, population-based cohort study on 4,043 patients
Creators: name: Wadström, Miriam G
name: Hailer, Nils P
name: Hailer, Yasmin D
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Background and purpose — Patients with pediatric hip diseases are more comorbid than the general population and at risk of premature, secondary osteoarthritis, often leading to total hip arthroplasty (THA). We investigated whether THA confers an increased mortality in this cohort. Patients and methods — We identified 4,043 patients with a history of Legg–Calvé–Perthes disease (LCPD), slipped capital femoral epiphysis (SCFE), or developmental dysplasia of the hip (DDH) in the Swedish Hip Arthroplasty Register (SHAR) between 1992 and 2012. For each patient, we matched 5 controls from the general population for age, sex, and place of residence, and acquired information on all participants’ socioeconomic background and comorbidities. Mortality after THA was estimated according to Kaplan–Meier, and Cox proportional hazard models were fitted to estimate adjusted hazard ratios (HRs) for the risk of death. Results — Compared with unexposed individuals, patients exposed to a THA due to pediatric hip disease had lower incomes, lower educational levels, and a higher degree of comorbidity but a statistically non-significant attenuation of 90-day mortality (HR 0.9; 95% CI 0.4–2.0) and a lower risk of overall mortality (HR 0.8; CI 0.7–0.9). Interpretation — Patients exposed to THA due to a history of pediatric hip disease have a slightly lower mortality than unexposed individuals. THA seems not to confer increased mortality risks, even in these specific patients with numerous risk factors.
Development of SNPs markers from pooled RAD-seq data and high throughput genotyping, applied to the study of several harvested population genetics in the Upper Maroni
Creators: name: DELORD, Chrystelle
name: LASSALLE, Gilles
name: LAUNEY, Sophie
name: Pierre-Yves LE BAIL
Publisher: name: F1000Research
Year: 2016

description: In a perspective of conservation, considering the state of genetic resources of species is often of critical importance. To this end, a main issue consists in the ability to cost-efficiently genotype a high number of molecular markers in a high number of individuals, so one reinforces the pertinence of subsequent biological interpretations. The prior challenge is the access to a catalog or relevant and suitable molecular markers, which could be particularly complex when considering non-model species for which genetic knowledge is scarce. One of our objectives is to develop a set of specific markers for several neotropical fish populations (Maroni river, French Guiana) whose dispersal abilities and population structuration are almost entirely unknown. Indeed those species are often of high cultural and alimentary value for autochtonous people, for instance Wayana amerindians who are hoping for a sustainable management of those artisanal fisheries.

Here, we present our strategy, that integrates RAD-seq of pooled individuals for SNP calling, and should make us able to cost-efficiently develop and genotype a reasonable number of SNPs markers for each species of interest, sufficient to adress population genetics issues. We mainly focused on some of the relevant questions one needs to think about before establishing  the computational process (pipeline) that will be adapted to extract those markers from NGS data. We also present some of the most widely used high-throughput genotyping methods, as well as their pros and cons.
title: Interlayer Exciton–Phonon Coupling in MoSe2/WSe2 Heterostructures
Creators: name: Garrity, Oisín
name: Brumme, Thomas
name: Bergmann, Annika
name: Korn, Tobias
name: Kusch, Patryk
name: Reich, Stephanie
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: exciton−phonon
subject: Raman
subject: TMDC
subject: DFT
subject: heterostructures
classificationCode: 530
subject: Physik

description: Transition metal dichalcogenide heterostructures have garnered strong interest for their robust excitonic properties, mixed light–matter states such as exciton-polaritons, and tailored properties, vital for advanced device engineering. Two-dimensional heterostructures inherit their physics from monolayers with the addition of interlayer processes that have been particularly emphasized for their electronic and optical properties. Here, we demonstrate the interlayer coupling of the MoSe2 phonons to WSe2 excitons in a WSe2/MoSe2 heterostructure using resonant Raman scattering. The WSe2 monolayer induces an interlayer resonance in the Raman cross-section of the MoSe2 A1g phonons. Frozen-phonon calculations within density functional theory reveal a strong deformation-potential coupling between the A1g MoSe2 phonon and the electronic states of the close-by WSe2 layer approaching 20% of the intralayer coupling to the MoSe2 electrons. Understanding the vibrational properties of van der Waals heterostructures requires going beyond the sum of their constituents and considering cross-material coupling.
SkIf: a tool for rapid identification of genes or regulators of interest
Creators: name: Briand, Martial
name: Gaborieau, Romain
name: Marie-Agnes Jacques
name: Barret, Matthieu
name: Boureau, Tristan
name: Gaillard, Sylvain
name: WG, Nicolas Chen
Publisher: name: F1000Research
Year: 2016

description: SkIf is a comparative genomics tool that detect genomic regions (from SNPs to genomic islands) specifically associated to a group of organisms (defined by the user).

SkIf identify specific sequences for a group of organisms sharing a common trait of interest.

The user uploads a library of sequences (DNA, RNA, or AA) then choose one reference sequence, and splits the library into two groups.

Each sequence is cut in k-mers (k is defined by the user), and an abundance matrix of all k-mers is constructed.

SkIf provide the list of k-mers specifically present or absent in the groups and coordinates of these specific k-mers on the reference.

SkIf was developed in C ++ and sequence reading is done using Bio++ bpp-seq library.

SkIf can be employed for studying polyphyletic groups. It can detect both convergent evolution and horizontal transfers.

SkIf can be used as a primary filter for further functional trait studies, or to develop specific tests for identification or detection of organisms presenting a given trait.
Students’ opinion towards the Pernkopf atlas: are the Italian students ready to know the history?
Creators: name: Gibelli, Daniele
name: Sforza, Chiarella
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2016
Subjects: anatomy; history of anatomy; ethics

description: The debate around Pernkopf’s atlas, the origin of bodies used to create its plates and the person of Eduard Pernkopf has involved with time academic authorities and university professors, and has shaken the anatomical scenario. However, no study has been so far performed concerning the opinion of students towards this sensitive and problematic issue. This article aims at exposing the results of an interview performed on 42 Italian medical students, after a self-chosen course of history of human anatomy, in order to ascertain the students’ opinion towards this important debate in the anatomic scenario. Results showed that 91% of students did not know the existence of Pernkopf’s atlas: 51% stated they would not use it, whereas for 65% it should be preserved for didactic purposes. Subjects who preferred the atlas to be banished justified their position mainly on the base of ethical reasons (25%); however, in a third of cases students were not able to give an answer. Twenty-two percent of students who agree with a preservation of the atlas would limit its use to historical studies. In 11% ethical issues were not considered important. In 52% of cases no opinion was given. Results show that the debate concerning Pernkopf’s atlas, at least among students, is at the very beginning: more efforts need to be performed in order to let the medical students know the history of the atlas and its importance in the scientific debate around the ethics in anatomy.
description: Italian Journal of Anatomy and Embryology, Vol 121, No 2 (2016)
Influence of body mass index and age on day-of-surgery discharge, prolonged admission, and 90-day readmission after fast-track unicompartmental knee arthroplasty
Creators: name: Jensen, Christian Bredgaard
name: Troelsen, Anders
name: Petersen, Pelle Baggesgaard
name: JØrgensen, Christoffer Calov
name: Kehlet, Henrik
name: Gromov, Kirill
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Background and purpose — The indications for unicompartmental knee arthroplasty (UKA) have become less restrictive and, today, high age and high BMI are not considered contraindications by many surgeons. While the influence of these patient characteristics on total knee arthroplasty is well documented, evidence on UKA is lacking. We investigated the effect of BMI and age on day of surgery (DOS) discharge, prolonged admission, and 90-day readmission following UKA surgery. Patients and methods — This retrospective cohort study included 3,897 UKA patients operated on between 2010 and 2018 in 8 fast-track arthroplasty centers. Patients were divided into 5 BMI groups and 5 age groups. Differences between groups in the occurrence of DOS discharge, prolonged admission > 2 days, and 90-day readmission was investigated using a chi-square test and mixed-effect models adjusted for patient characteristics using surgical center as a random effect. Results — Median LOS was 1 day. DOS discharge was achieved in 26% of patients with no statistically significant differences between BMI groups. DOS discharge was less likely in UKA patients aged > 70 years (age 71–80; odds ratio [OR] 0.7 [95% CI 0.6–0.9]). Prolonged admission was not affected by BMI or age in the adjusted analysis. 90-day readmission was more likely in patients with BMI > 35 (OR 1.9 [CI 1.1–3.1]) and patients aged 71–80 (OR 1.5 [CI 1.1–2.1]). Interpretation — Age > 70 years decreased the likelihood of DOS discharge after UKA. High BMI as well as advanced age increased the likelihood of 90-day readmission. This should be noted by surgeons operating on patients with high BMI and age.
Description of an optic spine on the sphenoid bone of camels and dromedaries
Creators: name: Fornazari, Gabrielle A.
name: Montiani-Ferreira, Fabiano
name: Silva, Jeverson C.
name: Barros, Ivan R.
name: Machado, Marcello Z.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2016
Subjects: anatomy; bony orbit; Camelus bactrianus; Camelus dromedaries; optic spine; sphenoid bone; comparative studies; mammals

description: Objective To describe the presence of an intraorbital cylindrical osseous structure (a spine) in two animal species: camel (Camelus bactrianus) and dromedary (Camelus dromedaries). A homologous osseous structure was previously observed in the large fruit-eating bat (Artibeus lituratus).
Procedures The bony anatomy of the orbital cavity was studied and quantified on macerated skulls of 3 camels and 2 dromedaries. Additionally, one macerated skull of a large fruit-eating bat (Artibeus lituratus) was used for comparative purposes.
Results The anatomic description of these unique intraorbital spine was made while studying the bony orbit of macerated skulls, and was considered homologous to that of the bat based on the same anatomic position (at the bone bridge that separates the optic canal and the sphenorbital fissure) and similarities in shape. We suggest the name optic spine of the sphenoid bone.
Discussion The novel observation of an optic spine on the sphenoid bone in camels and dromedaries (Artiodactyla), when combined with the previous finding of a similar anatomic structure in a bat (Chiroptera) suborder Microchiroptera, may provide further support to the close proximity of these two apparently very distinct animal orders in the phylogenetic tree, and may contribute to the understanding of bat evolution and provide new directions for future research. The function of this osseous spine remains to be investigated, although we hypothesize that the optic spine of the camelids may serve as an attachment site for extraocular muscles.
description: Italian Journal of Anatomy and Embryology, Vol 121, No 2 (2016)
Identifying Landscapes and their Formation Timescales: Comparing Knowledge and Confidence of Beginner and Advanced Geoscience Undergraduate Students
Creators: name: Jolley, Alison Rae
Publisher: name: The University of British Columbia
Year: 2010

description: The Landscape Identification and Formation Test (LIFT) was created in response to previous data from the Student Attitudes about Earth Science Survey (SAESS) at the University of British Columbia (Vancouver). The SAESS data suggested that upper-level students become less confident in landscape identification and formation timescales over the course of a term. The LIFT specifically probes the relationships among student confidence and knowledge in landscape identification and formation timescales and general knowledge in geologic time. The LIFT was validated with “think-aloud” interviews with students and correct answers were determined from interviews with experts. Results from the LIFT suggest that advanced students have higher conceptual knowledge, higher confidence in their knowledge, and are more self-aware than beginner students. Advanced students became more confident in landscape identification and formation timescales over the course of the term, contradicting the results seen in the previous administration of the SAESS. Students are better at identifying landscapes than assessing how long they take to form and are better with extreme timescales, two critical points that should be taken into consideration with future curricular reform.
The patellofemoral joint alignment in patients with symptomatic accessory navicular bone
Creators: name: Kalbouneh, Heba M.
name: Alkhawaldah, Abdullah O.
name: Alajoulin, Omar A.
name: Alsalem, Mohammad I.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2016
Subjects: Q angle; pes planus; patellofemoral joint; accessory navicular; navicular drop test

description: Quadriceps angle (Q angle) provides useful information about the alignment of the patellofemoral joint. The aim of the present study was to assess a possible link between malalignment of the patellofemoral joint and symptomatic accessory navicular (AN) bone as an underlying cause in early adolescence using Q angle measurements. This study was performed on patients presenting to the Foot and Ankle Clinic at the Jordanian Royal Medical Services because of pain on the medial side of the foot that worsened with activities or shoe wearing, with no history of knee pain, between September 2013 and April 2015. The Q angle was measured using a goniometer in 27 early adolescents aged 10-18 years diagnosed clinically and radiologically with symptomatic AN bone, only seven patients had associated pes planus deformity; the data were compared with age appropriate normal arched feet without AN. Navicular drop test (NDT) was used to assess the amount of foot pronation. The mean Q angle value among male and female patients with symptomatic AN with/without pes planus was significantly higher than in controls with normal arched feet without AN (p<0.05). Symptomatic AN feet were also associated with higher NDT values (p<0.001). The present findings suggest an early change in patellofemoral joint alignment in patients with symptomatic AN bone with/without arch collapse. Therefore, it is recommended that Q angle assessment should be an essential component of the examination in patients with symptomatic AN bone.
description: Italian Journal of Anatomy and Embryology, Vol 121, No 2 (2016)
title: Representation formulas and far-field behavior of time-periodic incompressible viscous flow around a translating rigid body
Creators: name: Eiter, Thomas
name: Silvestre, Ana Leonor
Publisher: name: Freie Universität Berlin
Year: 2025
Subjects: subject: Time-periodic Navier–Stokes flows
subject: Exterior domains
subject: Time-periodic Oseen fundamental solution
subject: Integral representation
subject: Asymptotic expansion
classificationCode: 510
subject: Mathematik

description: This paper is concerned with integral representations and asymptotic expansions of solutions to the time-periodic incompressible Navier–Stokes equations for fluid flow in the exterior of a rigid body that moves with constant velocity. Using the time-periodic Oseen fundamental solution, we derive representation formulas for solutions with suitable regularity. From these formulas, the decomposition of the velocity component of the fundamental solution into steady-state and purely periodic parts and their detailed decay rate in space, we deduce complete information on the asymptotic structure of the velocity and pressure fields.
Implant survival of 662 dual-mobility cups and 727 constrained liners in primary THA: small femoral head size increases the cumulative incidence of revision
Creators: name: Pakarinen, Oskari
name: Lainiala, Olli
name: Reito, Aleksi
name: Neuvonen, Perttu
name: Mäkelä, Keijo
name: Eskelinen, Antti
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Science Policy

description: Background and purpose — In total hip arthroplasty (THA), the risk for dislocation can be reduced using either dual-mobility cups (DMCs) or constrained liners (CLs). There are few studies comparing these concepts in primary THA. Therefore, we compared the cumulative incidence of revision in primary THA patients treated with DMC or CL with varying head sizes with conventional THA patients as reference group. Patients and methods — We performed a cohort study based on the Finnish arthroplasty register, comparing DMCs and CLs operated over the period 2000–2017. DMCs were divided into 2 groups based on the implant design: “DMC Trident” group (n = 399) and “DMC Others” group (n = 263). CLs were divided based on the femoral head size: “CL 36 mm” group (n = 425) and “CL < 36 mm” group (n = 302). All conventional primary THAs operated on in 2000–2017 with 28–36 mm femoral head were included as control group (“Conventional THA” group, n = 102,276). Implant survival was calculated by the corresponding cumulative incidence function with revision as the endpoint and death as competing event. Also, the prevalence of different reasons for revision was compared. Results — The 6-year cumulative incidence function estimates for the first revision were 6.9% (95% CI 4.0–9.7) for DMC Trident, 5.0% (CI 1.5–8.5) for DMC Others, 13% (CI 9.3–17) for CL < 36 mm, 6.3% (3.7–8.9) for CL 36 mm, and 4.7% (CI 4.5–4.8) for control group (conventional THA). The prevalence of dislocation revision was high (5.0%, CI 2.9–8.2) in the CL < 36 mm group compared with other groups. Interpretation — The DMC and CL 36 mm groups had promising mid-term survival rates, comparable to those of primary conventional THA group. The revision rate of CLs with < 36 mm head was high, mostly due to high prevalence of dislocation revisions. Therefore, CLs with 36 mm femoral head should be preferred over smaller ones.