cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Diversität und Hybridität im Management – Genese: von interpersonalen Gespannstrukturen zur intrapersonalen Hybridität mit rassenbedingten Gefährdungen
Creators: name: Schneider, Dietram
Publisher: name: Hochschule für angewandte Wissenschaften Kempten
Year: 2025
Subjects: subject: 10 Philosophie
subject: 33 Wirtschaft

description: Das Interesse an Diversität und Hybridität im Management entwickelte sich aus diversifizierenden und transnationalen Aktivitäten von Unternehmen. Nach interpersonalen Gespannstrukturen als Vorboten der Diversität baut der Hype um die Hybridität auf intrapersonale und kosmopolitische Attribuierungen auf, die rassentheoretische Gefahren provozieren.
description: Transnational corporate activities have opened the discourse on diversity and hybridity. Starting from classical interpersonal team structures, this paper extends from diversity to intrapersonal hybridity in management to the cosmopolitan elite and includes bastardization, which runs the risk of serving race-theoretical views.
Grammacephalus Haupt
Creators: name: Dai, Wu
name: Zhang, Yalin
name: Viraktamath, C. A.
name: Webb, M. D.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadellidae
Grammacephalus

description: Grammacephalus Haupt
Grammacephalus Haupt, 1929, type species Platymetopius pugio Noualhier
Remarks. The genus Grammacephalus was revised for the Afrotropical region by Linnavuori (1978), who described three new species and erected two new combinations. Later, two species were moved into the genus and one new species was added by Viraktamath (1981) and another by Viraktamath and Anantha Murthy (1999), all from the Indian subcontinent. The new species described below represents the first record of the genus from China and only the second Asian record outside of the Indian subcontinent; an undetermined female specimen from The Philippines was recorded by Webb & Godoy (1993).
Hosts. Species of Grammacephalus have been collected on species of Acacia (Leguminosae) and Zizyphus (Rhamnaceae) (Viraktamath, 1981), and the new species on Dodoneae viscosa (L.) (Sapindaceae)
description: Published as part of Dai, Wu, Zhang, Yalin, Viraktamath, C. A. & Webb, M. D., 2006, Two new Asian Scaphytopiini leafhoppers (Hemiptera: Cicadellidae: Deltocephalinae) with description of a new genus, pp. 37-44 in Zootaxa 1309 on page 38, DOI: 10.5281/zenodo.173819
Nysius helveticus Herrich-Schaeffer 1835
Creators: name: Ghahari, Hassan
name: Moulet, Pierre
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Lygaeidae
Nysius
Nysius helveticus

description: Nysius helveticus (Herrich-Schaeffer, 1835)
Distribution in Iran. Tehran (Linnavuori 2007). General distribution. Euro-Siberian.
description: Published as part of Ghahari, Hassan & Moulet, Pierre, 2012, An Annotated Catalog of the Iranian Lygaeoidea (excluding Berytidae and Piesmatidae) (Hemiptera: Heteroptera: Pentatomomorpha), pp. 1-33 in Zootaxa 3408 on page 7, DOI: 10.5281/zenodo.213702
MOESM2 of Human papillomavirus 16-specific cell-mediated immunity in children born to mothers with incident cervical intraepithelial neoplasia (CIN) and to those constantly HPV negative
Creators: name: Hanna-Mari Koskimaa
name: Paaso, Anna
name: Welters, Marij
name: Grénman, Seija
name: Syrjänen, Kari
name: Burg, Sjoerd
name: Syrjänen, Stina
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 2. The oral HPV and HPV antibodies of the case-children from the baseline to 6 years (72 months). Oral HPV was tested at every time point, serum antibodies at the age of 1, 2, 6, 12, 24, and 36 months. Number in the box indicates the detected HPV type. Negative result is indicated by x and no sample by empty bar.
Additional file 3: of Design programmes to maximise participant engagement: a predictive study of programme and participant characteristics associated with engagement in paediatric weight management
Creators: name: Nobles, James
name: Griffiths, Claire
name: Pringle, Andy
name: Gately, Paul
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Univariable Regression Models. (PDF 411 kb)
Nysius senecionis subsp. senecionis Shilling 1829
Creators: name: Ghahari, Hassan
name: Moulet, Pierre
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Lygaeidae
Nysius
Nysius senecionis
Nysius senecionis senecionis (shilling, 1829)

description: Nysius senecionis senecionis (Shilling, 1829)
Distribution in Iran. Ardabil (Modarres Awal 1987), East Azarbaijan (Sadeghi et al. 2009; Khaghaninia et al. 2010a, b, 2011), Hamadan (Samin et al. 2011), West Azarbaijan (Sakenin et al. 2010), Zanjan (Askari et al. 2009). General distribution. Trans Palearctic, known in Tropical Africa and Republic of South Africa.
description: Published as part of Ghahari, Hassan & Moulet, Pierre, 2012, An Annotated Catalog of the Iranian Lygaeoidea (excluding Berytidae and Piesmatidae) (Hemiptera: Heteroptera: Pentatomomorpha), pp. 1-33 in Zootaxa 3408 on page 7, DOI: 10.5281/zenodo.213702
Investigation of the electrochemical behavior of cysteine by hyphenation of electrochemistry and mass spectrometry
Creators: name: Eidenschink, Johannes
name: Bagherimetkazini, Seyedehelahe
name: Matysik, Frank-Michael
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: ASSISTED INJECTION; CAPILLARY; COMBINATION; SIMULATION; Capillary electrophoresis; Electrochemistry; Mass spectrometry; Redox studies; Screen-printed electrodes
subject: 540 Chemie

description: The identification of the reaction product species stands out as one of the main limitations of the classical electrochemical techniques. This can be overcome by the combination of electrochemistry (EC) to mass spectrometry (MS). Moreover, the method can be further enhanced by implementing a separation technique between EC and MS. In the present work, the oxidation behavior of cysteine with coupling EC directly to MS (real-time EC-MS) or by implementing capillary electrophoresis (CE), to separate the analytes before the injection into the mass spectrometer, is investigated. Electrochemical measurements and pre-treatment were applied on screen-printed electrodes (SPEs) based on carbon. Direct EC-MS measurements were carried out with a modified flow cell, while online EC-CE-MS studies of cysteine oxidation were conducted with a custommade setup. An electrochemical conversion yield for cysteine of up to 69% was found. Cystine, cysteic acid, and cysteine sulfinic acid were found as oxidation products. The identification of these product species was carried out according to their migration behavior in CE, and mass-to-charge ratios in addition to their isotopic patterns shown in the MS spectra. [GRAPHICS] .
Photochromic Fentanyl Derivatives for Controlled μ-Opioid Receptor Activation
Creators: name: Lahmy, Ranit
name: Hübner, Harald
name: Schmidt, Maximilian F.
name: Lachmann, Daniel
name: Gmeiner, Peter
name: König, Burkhard
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: arylazopyrazoles • fentanyl • μ-opioid receptor • Gprotein- coupled receptor • photopharmacology
subject: 540 Chemie

description: Photoswitchable ligands as biological tools provide an opportunity to explore the kinetics and dynamics of the clinically relevant µ-opioid receptor. These ligands can potentially activate and deactivate the receptor when desired, using light. Spatial and temporal control of biological activity allows for application in a diverse range of biological investigations. Photoswitchable ligands have been developed in this work, modeled on the known agonist fentanyl, with the aim of expanding the current ‘toolbox’ of fentanyl photoswitchable ligands. In doing so, ligands have been developed that change geometry (isomerize) upon exposure to light, with varying photophysical and biochemical properties. This variation in properties may be valuable in further studying the functional significance of the µ-opioid receptor.
Sikhamani Viraktamath & Webb
Creators: name: Dai, Wu
name: Zhang, Yalin
name: Viraktamath, C. A.
name: Webb, M. D.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadellidae
Sikhamani

description: Sikhamani Viraktamath & Webb gen. nov.
Type species: Sikhamani delicatula sp. nov.
Small leafhoppers 5.00 mm long. Ochraceous with dark brown markings.
Head narrower than pronotum, conically produced anteriorly. Vertex longer medially than interocular width, flat, transition between vertex and face angular but not carinate. Face longer than wide, frontoclypeus 1.7 times as wide at antennal base as at apex. Clypellus wider near apex than at base, extending beyond genal curve. Pronotum widened posteriorly, about twice as wide as long, about as long as vertex, lateral margin carinate. Scutellum slightly longer than pronotum. Forewing with three subapical and three apical cells, outer subapical cell almost triangular, inner subapical cell open behind, a series of 8 reflexed veins to costa. Arrangement of setae on hind tibia: R1 18±2, R2 14±1, R3 18±1. Hind basitarsus with 4 platellae on distal transverse row of setae.
Male pygophore longer than high, with a mesal process directed mesally, long setae confined to caudal half. Tenth segment long, sclerotized. Subgenital plate elongate, triangular with a row of marginal setae. Style with broad anterior part, subapical lobe discernable but not well­developed, apophysis of style elongate, tapering caudally. Connective fused with aedeagus, its arms close together, with a distal spinelike paraphysis. Aedeagus complex, with stout preatrium and platelike basal processes, shaft very slender, tubular with apical gonopore.
Remarks: In the key to genera of Scaphytopiini of the Indian subcontinent by Viraktamath and Anantha Murthy (1999), Sikhamani keys out to Sudhamruta Viraktamath and Anantha Murthy. It differs from Sudhamrua in having cylindrical apophysis of style, well developed preatrium, and basal processes to the aedeagal shaft, and arcuate arms of the connective.
Etymology. The generic name is to be treated as an arbitrary combination of letters, and the gender is feminine.
description: Published as part of Dai, Wu, Zhang, Yalin, Viraktamath, C. A. & Webb, M. D., 2006, Two new Asian Scaphytopiini leafhoppers (Hemiptera: Cicadellidae: Deltocephalinae) with description of a new genus, pp. 37-44 in Zootaxa 1309 on pages 41-43, DOI: 10.5281/zenodo.173819
Nysius senecionis subsp. aegyptiacus Priesner & Alfieri 1953
Creators: name: Ghahari, Hassan
name: Moulet, Pierre
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Lygaeidae
Nysius
Nysius senecionis
Nysius senecionis aegyptiacus priesner & alfieri, 1953

description: Nysius senecionis aegyptiacus Priesner & Alfieri, 1953
Distribution in Iran. Hormozgan (Linnavuori 2004).
General distribution. Eremian, Egypt, Arabic peninsula; known in Sudanese region.
Comments. According to Péricart (1998a) there are 7 samples in the typical series, 2 of them really are senecionis aegyptiacus and 5 belong to nominal form; so he synonymized S. aegyptiacus, a name resurrected by Linnavuori (2004).
description: Published as part of Ghahari, Hassan & Moulet, Pierre, 2012, An Annotated Catalog of the Iranian Lygaeoidea (excluding Berytidae and Piesmatidae) (Hemiptera: Heteroptera: Pentatomomorpha), pp. 1-33 in Zootaxa 3408 on page 7, DOI: 10.5281/zenodo.213702
Additional file 9: of Cultivation of stable, reproducible microbial communities from different fecal donors using minibioreactor arrays (MBRAs)
Creators: name: Auchtung, Jennifer
name: Robinson, Catherine
name: Britton, Robert
Publisher: name: Figshare
Year: 2015
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology

description: Analysis of abundance of core OTUs identified in fecal donor C MBRA communities as a function of time in culture. Heatmap presenting abundance of OTUs that were identified as present in individual core communities for MBRAs inoculated with donor C as well as OTUs abundant in the donor C fecal sample.
Sikhamani delicatula Viraktamath & Webb, sp. nov.
Creators: name: Dai, Wu
name: Zhang, Yalin
name: Viraktamath, C. A.
name: Webb, M. D.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadellidae
Sikhamani
Sikhamani delicatula

description: Sikhamani delicatula Viraktamath & Webb sp. nov.
Figs 10–23.
Ochraceous with pale brown and dark brown markings (Figs. 10–13).
Male genitalia: Pygophore lobe with slightly oblique caudal margin, caudodorsal angle rounded, with setae restricted to caudodorsal area, and mesal sclerotized process having a basal stem with anterior and mesal projections distally. Style with broad anterior part, apophysis either bent distally (specimens from Nepal) or prolonged to an acute apex (specimen from Tonkin). Connective arms of the Y either close together or slightly separated, paraphysis variable in curvature and length. Preatrium and dorsal apodeme of aedeagus well­developed, variable in thickness and length, platelike, ventrolateral processes to shaft variable in curvature and width, laterocaudal angle produced into a hornlike process; aedeagal shaft slender, curved caudodorsally, its basal 0.25–0.5 flanked by ventrolateral plate­like processes.
Measurements: Male 5.00 mm long, 1.72 mm wide across eyes, 1.82 mm wide across hind margin of head and 2.00 mm wide across hind margin of pronotum.
Material examined: Holotype ɗ, NEPAL: Pokhara, 910 m, 18–27.ix. [19]65, L.W. Quate, Malaise Trap (BPBM). Paratypes: 11 ɗ, data as for holotype (9 ɗ in BPBM, 2 ɗ in UAS, 2 ɗ in BMNH). Other material: LAOS: 1 ɗ, Vientiane Prov. Ban van Eue, 31.i.1967, Native Collector, Bishop Museum (BPBM). TONKIN: 1 ɗ, Patham, at light, 4.xii. [19]29, R. Wheeler (IRSNB). CHINA: 3 ɗ, Yunnan, Menglun, 19.v.1991 and 6.vi.1991, Wang Yinglun and Tian Rungang (NWAFU).
Remarks. Externally S. delicatula resembles Thryaksha recurvatus Viraktamath & Anantha Murthy, but differs in the pronotal coloration and in the structure of male genitalia. Although there is considerable variation in the male genitalia among the specimens examined, all are identical externally and are considered to belong to the same species.
description: Published as part of Dai, Wu, Zhang, Yalin, Viraktamath, C. A. & Webb, M. D., 2006, Two new Asian Scaphytopiini leafhoppers (Hemiptera: Cicadellidae: Deltocephalinae) with description of a new genus, pp. 37-44 in Zootaxa 1309 on page 43, DOI: 10.5281/zenodo.173819
Data from: Building Earth with pebbles made of chondritic components
Creators: name: Garai, Susmita
name: Olson, Peter
name: Sharp, Zachary
Publisher: name: Zenodo
Year: 2024
Subjects: pebble accretion
chondritic components
chondrules
metal grains
chondrites
Earth's major element composition

description: Pebble accretion provides new insights into Earth's building blocks and early protoplanetary disk conditions. Here, we show that mixtures of chondritic components: metal grains, chondrules, calcium-aluminum-rich inclusions (CAIs), and amoeboid olivine aggregates (AOAs) match Earth's major element composition (Fe, Ni, Si, Mg, Ca, Al, O) within uncertainties, whereas no combination of chondrites and iron meteorites does. Our best fits also match the e54Cr and e50Ti values of Earth precisely, whereas the best fits for chondrites, or components with a high proportion of E chondrules, fail to match Earth. In contrast to some previous studies, our best-fitting component mixture is predominantly carbonaceous, rather than enstatite chondrules. It also includes 15 wt% of early-formed refractory inclusions (CAIs + AOAs), which is similar to that found in some C chondrites (CO, CV, CK), but notably higher than NC chondrites. High abundances of refractory materials are lacking in NC chondrites, because they formed after the majority of refractory grains were either drawn into the Sun or incorporated into terrestrial protoplanets via pebble accretion. We show that combinations of Stokes numbers of chondritic components build 0.35-0.7 Earth masses in 2 My in the Hill regime accretion, for a typical pebble column density of 1.2 kg/m2 at 1 au. However, a larger or smaller column density leads to super-Earth or moon-mass bodies, respectively. Our calculations also demonstrate that a few My of pebble accretion with these components yields a total protoplanet mass inside 1 au exceeding the combined masses of Earth, Moon, Venus, and Mercury. Accordingly, we conclude that pebble accretion is a viable mechanism to build Earth and its major element composition from primitive chondritic components within the solar nebula lifetime.
description: Funding provided by: University of New MexicoROR ID: https://ror.org/041ndzj79Award Number: EAR1953992
Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2
Creators: name: Willkomm, Sarah
name: Jakob, Leonhard
name: Kramm, Kevin
name: Graus, Veronika
name: Neumeier, Julia
name: Meister, Gunter
name: Grohmann, Dina
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: STRUCTURAL BASIS; GUIDE RNA; CRYSTAL-STRUCTURE; TARGET RNAS; MICRORNA; MESSENGER; PROTEINS; RISC; RECOGNITION; CLEAVAGE;
subject: 570 Biowissenschaften, Biologie
subject: 615 Pharmazie

description: Human Argonaute 2 (hAgo2) constitutes the functional core of the RNA interference pathway. Guide RNAs direct hAgo2 to target mRNAs, which ultimately leads to hAgo2-mediated mRNA degradation or translational inhibition. Here, we combine site-specifically labeled hAgo2 with time-resolved single-molecule FRET measurements to monitor conformational states and dynamics of hAgo2 and hAgo2-RNA complexes in solution that remained elusive so far. We observe dynamic anchoring and release of the guide's 3'-end from the PAZ domain during the stepwise target loading process even with a fully complementary target. We find differences in structure and dynamic behavior between partially and fully paired canonical hAgo2-guide/target complexes and the miRNA processing complex formed by hAgo2 and pre-miRNA451. Furthermore, we detect a hitherto unknown conformation of hAgo2-guide/target complexes that poises them for target-directed miRNA degradation. Taken together, our results show how the conformational flexibility of hAgo2-RNA complexes determines function and the fate of the ribonucleoprotein particle. Single-molecule FRET measurements provide detailed insights into the conformational states and dynamics of human Argonaute 2 that are required for its function at the core of the eukaryotic RNA silencing pathway.
Hybrid Ensemble-Based Travel Mode Prediction
Creators: name: Golik, Paweł
name: Grzenda, Maciej
name: Sienkiewicz, Elżbieta
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Travel mode choice (TMC) prediction, which can be formulated as a classification task, helps in understanding what makes citizens choose different modes of transport for individual trips. This is also a major step towards fostering sustainable transportation. As behaviour may evolve over time, we also face the question of detecting concept drift in the data. This necessitates using appropriate methods to address potential concept drift. In particular, it is necessary to decide whether batch or stream mining methods should be used to develop periodically updated TMC models. To address the challenge of the development of TMC models, we propose the novel Incremental Ensemble of Batch and Stream Models (IEBSM) method aimed at adapting travel mode choice classifiers to concept drift possibly occurring in the data. It relies on the combination of drift detectors with batch learning and stream mining models. We compare it against batch and incremental learners, including methods relying on active drift detection. Experiments with varied travel mode data sets representing both city and country levels show that the IEBSM method both detects drift in travel mode data and successfully adapts the models to evolving travel mode choice data. The method has a higher rank than batch and stream learners.
description: This preprint has not undergone peer review or any post-submission improvements or corrections. The Version of Record of this contribution is published in Advances in Intelligent Data Analysis XXII. IDA 2024. Lecture Notes in Computer Science, vol 14641. Springer, and is available online at Cham https://doi.org/10.1007/978-3-031-58547-0_16 The preprint includes 12+22 pages, 1+1 figures
Nysius thymi Wolff 1804
Creators: name: Ghahari, Hassan
name: Moulet, Pierre
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Lygaeidae
Nysius
Nysius thymi

description: Nysius thymi (Wolff, 1804)
Distribution in Iran. East Azarbaijan (Ghahari et al. 2010c), Golestan, Guilan, Tehran (Linnavuori 2007). General distribution. Holarctic.
description: Published as part of Ghahari, Hassan & Moulet, Pierre, 2012, An Annotated Catalog of the Iranian Lygaeoidea (excluding Berytidae and Piesmatidae) (Hemiptera: Heteroptera: Pentatomomorpha), pp. 1-33 in Zootaxa 3408 on page 7, DOI: 10.5281/zenodo.213702
MOESM1 of Human papillomavirus 16-specific cell-mediated immunity in children born to mothers with incident cervical intraepithelial neoplasia (CIN) and to those constantly HPV negative
Creators: name: Hanna-Mari Koskimaa
name: Paaso, Anna
name: Welters, Marij
name: GrĂŠnman, Seija
name: SyrjĂ¤Nen, Kari
name: Burg, Sjoerd
name: SyrjĂ¤Nen, Stina
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Proliferative T-cell responses against peptide pools of HPV16 E2, E6 and E7 of 31 children. The box is bounded on the top by the third quartile, the bottom by the first quartile, and divided by the median. The minimum and maximum are indicated by the whiskers. If three or fewer values are detected the median and/or min and max values are connected with vertical line.
Epiblemum palmarum Hentz 1832
Creators: name: David B. Richman
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Epiblemum
Epiblemum palmarum

description: Attus Walckenaer 1805 (applied to nearly all salticids – junior synonym of Salticus Latreille 1804) Epiblemum Hentz 1832 (applied to Salticus as well as Hentzia)
Hentzia Marx 1883, type species palmarum (Hentz) 1832.
Wala Keyserling 1885, type species palmarum (Hentz) 1832. Synonomy: Bryant 1940.
Anoka Peckham and Perckham 1893, type species vernalis Peckham and Peckham 1893. Synonomy: Bryant 1940.
Parahentzia Bryant 1943, type species mandibularis Bryant 1943. Synonomy: Richman 1989.
Maeviobeata Caporiacco 1847, type species charitonovi Caporiacco 1947 (= Anoka parallela Peckham and Peckham 1894.) Synonomy: Richman 1989.
Type species. — Epiblemum palmarum Hentz 1832, original
designation
description: Published as part of David B. Richman, 2010, A new species and new records of Hentzia (Araneae: Salticidae: Dendryphantinae) from the United States, pp. 73-78 in The Journal of Arachnology 38 on page 73
Orsillus depressus Mulsant & Rey 1852
Creators: name: Ghahari, Hassan
name: Moulet, Pierre
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Lygaeidae
Orsillus
Orsillus depressus

description: Orsillus depressus (Mulsant & Rey, 1852)
Distribution in Iran. Guilan (Linnavuori 2007).
General distribution. Holomediterranean, extending to Central Europe, Southern Russia, Ukraine, Turkey, Caucasus, and Middle Asia.
Comments. On Juniperus spp., especially Juniperus excelsa (Linnavuori 2007).
description: Published as part of Ghahari, Hassan & Moulet, Pierre, 2012, An Annotated Catalog of the Iranian Lygaeoidea (excluding Berytidae and Piesmatidae) (Hemiptera: Heteroptera: Pentatomomorpha), pp. 1-33 in Zootaxa 3408 on page 7, DOI: 10.5281/zenodo.213702
Additional file 7: Figure S4. of Transcription analysis of neonicotinoid resistance in Mediterranean (MED) populations of B. tabaci reveal novel cytochrome P450s, but no nAChR mutations associated with the phenotype
Creators: name: Ilias, Aris
name: Lagnel, Jacques
name: Kapantaidaki, Despoina E.
name: Roditakis, Emmanouil
name: Tsigenopoulos, Costas S.
name: Vontas, John
name: Tsagkarakou, Anastasia
Publisher: name: Figshare
Year: 2015
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: PCA plot. Overall similarity between samples using mapped reads on all contigs of the reference transcriptome (DESeq). The global gene expression pattern shows a clear separation between the susceptible and the three resistant strains. The higher correlation was observed among biological replicates of the same strain followed by the correlation between samples of the GR4_AP and the GR4_AS strains. The higher variance was found within strain R_GR4_AS: one biological replicate is closer to the parental strain R_GR4_AP while the two others are separated indicating signals of selection under insecticide pressure. (PDF 17 kb)
Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition
Creators: name: Winkler, René
name: Mägdefrau, Ann-Sophie
name: Piskor, Eva-Maria
name: Kleemann, Markus
name: Beyer, Mandy
name: Linke, Kevin
name: Hansen, Lisa
name: Schaffer, Anna-Maria
name: Hoffmann, Marina E.
name: Poepsel, Simon
name: Heyd, Florian
name: Beli, Petra
name: Möröy, Tarik
name: Mahboobi, Siavosh
name: Krämer, Oliver H.
name: Kosan, Christian
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: UBIQUITIN-MEDIATED PROTEOLYSIS; C-MYC; DOWN-REGULATION; HDAC6; CANCER; TUBULIN; ACETYLATION; EXPRESSION; LINES; NOXA;
subject: 540 Chemie

description: Overexpression of MYC is a genuine cancer driver in lymphomas and related to poor prognosis. However, therapeutic targeting of the transcription factor MYC remains challenging. Here, we show that inhibition of the histone deacetylase 6 (HDAC6) using the HDAC6 inhibitor Marbostat-100 (M-100) reduces oncogenic MYC levels and prevents lymphomagenesis in a mouse model of MYC-induced aggressive B-cell lymphoma. M-100 specifically alters protein-protein interactions by switching the acetylation state of HDAC6 substrates, such as tubulin. Tubulin facilitates nuclear import of MYC, and MYC-dependent B-cell lymphoma cells rely on continuous import of MYC due to its high turn-over. Acetylation of tubulin impairs this mechanism and enables proteasomal degradation of MYC. M-100 targets almost exclusively B-cell lymphoma cells with high levels of MYC whereas non-tumor cells are not affected. M-100 induces massive apoptosis in human and murine MYC-overexpressing B-cell lymphoma cells. We identified the heat-shock protein DNAJA3 as an interactor of tubulin in an acetylation-dependent manner and overexpression of DNAJA3 resulted in a pronounced degradation of MYC. We propose a mechanism by which DNAJA3 associates with hyperacetylated tubulin in the cytoplasm to control MYC turnover. Taken together, our data demonstrate a beneficial role of HDAC6 inhibition in MYC-dependent B-cell lymphoma.
IMMUNITET TIZIMI ORGANIZMNI HIMOYA QILISHI VA HOZIRGI DAVRDA IMMUNITETNI SAQLASH VA MUSTAHKAMLASH BO'YICHA YANGICHA YONDASHUVLAR
Creators: name: Toshkent Tibbiyot Akademiyasi Termiz Filiali  talabasi  Boyxonov Shohruh Bo`riboy o`g`li , O`qituvchi  Xamrayev Rashid
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqolada immunitet tizimi va uning inson organizmidagi ahamiyati, shuningdek, immunitetni mustahkamlashning zamonaviy yondashuvlari ko'rib chiqilgan. Immunitet organizmni turli infeksiyalar va kasalliklar, shu jumladan viruslar, bakteriyalar va boshqa zararlilardan himoya qilishda muhim rol o'ynaydi. Maqolada immunitet tizimining ishlash prinsiplari, uni kuchaytirish uchun zarur bo'lgan omillar, masalan, to'g'ri ovqatlanish, jismoniy faoliyat, stressni boshqarish va yaxshi uyqu haqida batafsil ma'lumot berilgan. Shuningdek, immunitetni pasaytirishi mumkin bo'lgan omillar va yangi tibbiy yondashuvlar, jumladan, immunomodulyatorlar va gen terapiyasining ahamiyati haqida ham so'z yuritilgan. Ushbu maqola sog'liqni saqlashni yaxshilash, immunitetni mustahkamlash va kasalliklarni oldini olish bo'yicha foydali tavsiyalarni o'z ichiga oladi.

   Kalit so'zlar:Immunitet tizimi,tug'ma va orttirilgan immunitet, lizotsim,immunoglobinlar,nryramin va gialuron kislotalri,plakin, eritrin,makrofaglar,immunomodulyatorlar,stress va immunitet,vitaminlar va mineral moddalar,biologik qo'llab-quvvatlash,gen terapiyasi
Additional file 1: of Design programmes to maximise participant engagement: a predictive study of programme and participant characteristics associated with engagement in paediatric weight management
Creators: name: Nobles, James
name: Griffiths, Claire
name: Pringle, Andy
name: Gately, Paul
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: TIDieR Framework: A Comprehensive Overview of the MoreLife Programme. (PDF 367 kb)
Additional file 14: of Cultivation of stable, reproducible microbial communities from different fecal donors using minibioreactor arrays (MBRAs)
Creators: name: Auchtung, Jennifer
name: Robinson, Catherine
name: Britton, Robert
Publisher: name: Figshare
Year: 2015
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Distribution of sequences in shared OTUs across replicate samples prepared by different methods. A table providing percent differences in abundance of OTUs and sequences based upon sample preparation method and a graph plotting the abundance of different taxa across replicate samples prepared with different methods.
Ortholomus punctipennis Herrich-Schaeffer 1829
Creators: name: Ghahari, Hassan
name: Moulet, Pierre
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Lygaeidae
Ortholomus
Ortholomus punctipennis

description: Ortholomus punctipennis (Herrich-Schaeffer, 1829)
Distribution in Iran. East Azarbaijan (Ghahari et al. 2011), Guilan (Linnavuori 2007), Hamadan (Samin et al. 2011).
General distribution. Euro-Siberian.
description: Published as part of Ghahari, Hassan & Moulet, Pierre, 2012, An Annotated Catalog of the Iranian Lygaeoidea (excluding Berytidae and Piesmatidae) (Hemiptera: Heteroptera: Pentatomomorpha), pp. 1-33 in Zootaxa 3408 on page 8, DOI: 10.5281/zenodo.213702
Additional file 1: of The impact of electronic records on patient safety: a qualitative study
Creators: name: Clarke, Arabella
name: Adamson, Joy
name: Watt, Ian
name: Sheard, Laura
name: Cairns, Paul
name: Wright, John
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy

description: Topic guide for interviews with NHS staff. Topic guide used for the qualitative interviews with study participants. Within the main text the topic guide is referenced as Additional file 1. (DOCX 18 kb)
Hentzia fimbriata F.O. Pickard-Cambridge 1901
Creators: name: David B. Richman
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Salticidae
Hentzia
Hentzia fimbriata

description: Hentzia fimbriata (F.O. Pickard-Cambridge 1901)
Fig. 16
This species was adequately described by Richman (1989, pp. 306–307, figs. 37–43), but a few specimens have been collected in the United States, far north of the previously northernmost known record in Nayarit, Mexico. Based on the specimens examined it is possible that H. pima Richman 1989 is a junior synonym of H. fimbriata, as the photograph of the epigynum (Fig. 17) of a female collected from east of Sycamore Canyon resembles fig. 65 in Richman (1989), except for the openings, which in the Sycamore Canyon female are typical for H. fimbriata. The dorsal pattern of the abdomen of H. pima (Richman 1989, fig. 64) is very similar to that of the female from near Sycamore Canyon. The males collected in Sycamore Canyon and Florida Canyon closely match those of H. fimbriata. I suspect that H. pima is based on an slightly aberrant female, especially because of the relatively close geographical proximity of the type specimen from the Baboquivari Mountains. However, more material is needed either to verify H. pima as a separate species or to synonymize it with H. fimbriata.
New Records. — USA: Arizona: 1 female, Santa Cruz County, Coronado National Forest, 3–6 km east of Sycamore Canyon in Pajarito Mountains (ca 31°20ʹ0 8ʺN, 111°0 8ʹ46ʺW, ca 1372 m), 29 July 1999, D.B. Richman (beating oak) (NMSU AM 832); 1 male, Sycamore Canyon, Hank and Yank Springs (ca 31°25ʹ39ʺN, 111°11ʹ33ʺW), 18 August 1992, W. Maddison, G.B.Edwards & M. McMahon (92-045); 1 male, Pima Co.: Santa Rita Mountains, Florida Canyon, Florida Station (ca 31° 46ʹ28ʺ N, 110 °52ʹ0 4ʺW), 13 April 1991, W. Maddison (91-014); 1 female, Pima Co., Santa Rita Mountains, Florida Canyon, Florida Station (ca 31° 46ʹ28ʺN, 110 °52ʹ0 4ʺW), 3 March 1994, female (presumably H. fimbriata, not identified) collected by W. Maddison (94-008) (last three records all in W. Maddison collection, University of British Columbia, Vancouver, British Columbia, Canada).
description: Published as part of David B. Richman, 2010, A new species and new records of Hentzia (Araneae: Salticidae: Dendryphantinae) from the United States, pp. 73-78 in The Journal of Arachnology 38 on page 76
Kleidocerys privignus Horvath 1894
Creators: name: Ghahari, Hassan
name: Moulet, Pierre
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Lygaeidae
Kleidocerys
Kleidocerys privignus

description: Kleidocerys privignus (Horváth, 1894)
Distribution in Iran. Guilan (Linnavuori 2007).
General distribution. Known from Caucasus and Central Europe.
Comments. A questionable species which can be separated from K. resedae only by its biology. K. privignus lives only on Alnus sp, but the host plants of K. resedae are more varied (see Péricart 1998a).
description: Published as part of Ghahari, Hassan & Moulet, Pierre, 2012, An Annotated Catalog of the Iranian Lygaeoidea (excluding Berytidae and Piesmatidae) (Hemiptera: Heteroptera: Pentatomomorpha), pp. 1-33 in Zootaxa 3408 on page 8, DOI: 10.5281/zenodo.213702
Additional file 14: Table S6. of A machine learning strategy for predicting localization of post-translational modification sites in protein-protein interacting regions
Creators: name: Thammakorn Saethang
name: D. Payne
name: Yingyos Avihingsanon
name: Trairak Pisitkun
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Common overlapping indices of three PTM-specific optimized sets of indices. (DOCX 20 kb)
Hentzia palmarum Hentz 1831
Creators: name: David B. Richman
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Salticidae
Hentzia
Hentzia palmarum

description: Hentzia palmarum (Hentz 1831)
Figs. 11–15
In the process of comparing this species to specimens of Hentzia alamosa new species from Big Bend Ranch State Park, Presidio County, Texas, several new records were discovered. For a description of this species see Richman (1989, pp. 296– 302, figs. 16–27).
New Records. — USA: Texas: 1 male, 4 females, Edwards County, near Rock Springs (30°0 1ʹ29ʺN, 100°12ʹ21ʺW), January 1994; 3 females, Mason County, near Mason (ca 30°44ʹ56ʺN, 99°13ʹ50ʺW), January 1994; 1 male, 5 females, Zavala County, near Nueces (ca 28°47ʹ18ʺN, 99°49ʹ0 9ʺW), January 1994. All specimens were taken from irrigation tubes in pecan orchards by J. W. Stewart. All specimens deposited in TAMUIC.
Discussion. —The scattered distribution of most Hentzia species in the western United States and Mexico, usually in riparian areas, suggests speciation events by the founder effect, with a few individuals being accidentally introduced (perhaps by storms) to isolated favorable habitats. The other possibility may be isolation of populations of more widely spread species (such as H. palmarum or H. fimbriata) in refugia because of desert expansion, followed by subsequent speciation events. The presence of Hentzia fimbriata in Sycamore Canyon is an exception to the isolated populations in other parts of the southwesten USA and northwestern Mexico, as this species is widespread in Mexico. It is likely that its distribution follows the Sierra Madre and the watersheds of Mexican rivers draining into the Gulf of California. Sycamore Canyon, which drains into the Rio Altar in the Rio de la Concepcion drainage in Sonora, and where the U.S. specimens of H. fimbriata have been collected, is unusual in the variety of jumping spiders found there that are primarily associated with other geographical ranges. These include Zygoballus rufipes Peckham & Peckham 1885 (Mexico and eastern United States), Phidippus tux Pinter 1970 (central Mexico), and Sarinda hentzi (Peckham & Peckham 1892) (eastern United States) (all collected by the author). Because of the similar morphological features, future research on the genus Hentzia should include mitochondrial DNA analysis of as many species as possible in order to clear up the actual phylogenetic source and relationships of these species, especially in the palmarum species group. This is unfortunately beyond the scope of this paper and would require collection of fresh material from Cuba and Mexico, as well as the USA, even if limited to the palmarum group.
description: Published as part of David B. Richman, 2010, A new species and new records of Hentzia (Araneae: Salticidae: Dendryphantinae) from the United States, pp. 73-78 in The Journal of Arachnology 38 on pages 76-77
Cymus claviculus Fallen 1807
Creators: name: Ghahari, Hassan
name: Moulet, Pierre
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cymidae
Cymus
Cymus claviculus

description: Cymus claviculus (Fallén, 1807)
Distribution in Iran. Fars, Isfahan (Linnavuori 2011), Guilan (Linnavuori 2007). General distribution. Euro-Siberian.
Comments. On Juncaceae, Cyperaceae, Caryophyllaceae, and Polygonaceae (Linnavuori 2011).
description: Published as part of Ghahari, Hassan & Moulet, Pierre, 2012, An Annotated Catalog of the Iranian Lygaeoidea (excluding Berytidae and Piesmatidae) (Hemiptera: Heteroptera: Pentatomomorpha), pp. 1-33 in Zootaxa 3408 on page 8, DOI: 10.5281/zenodo.213702
Additional file 8: of Cultivation of stable, reproducible microbial communities from different fecal donors using minibioreactor arrays (MBRAs)
Creators: name: Auchtung, Jennifer
name: Robinson, Catherine
name: Britton, Robert
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology

description: Analysis of abundance of core OTUs identified in fecal donor B MBRA communities as a function of time in culture. Heatmap presenting abundance of OTUs that were identified as present in individual core communities for MBRAs inoculated with donor B as well as abundant in the donor B fecal sample.
Steuerung der ultraschnellen Öffnungs‐ und Schließungsdynamik eines photochromen Koordinationskäfigs durch Gastmoleküle
Creators: name: Artmann, Kevin
name: Li, Ru‐Jin
name: Juber, Selina
name: Benchimol, Elie
name: Schäfer, Lars V.
name: Clever, Guido H.
name: Nuernberger, Patrick
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: Einschluss · Käfigverbindungen · Photoschalter · Supramolekulare Chemie · Ultraschnelle Spektroskopie
subject: 540 Chemie

description: Photochemische Studien über supramolekulare Wirte, die kleine Gastmoleküle einkapseln können, konzentrieren sich zumeist auf drei Aspekte: Die Photoschaltung des Käfigs, um den Gast freizusetzen oder einzufangen, die Wirkung der Käfigumgebung auf den Gast und die lichtinduzierte Exzitonen- oder Ladungsübertragung innerhalb der Käfigstruktur. Hier nutzen wir ultraschnelle Spektroskopie, um zu untersuchen, wie der Gast die Photoschaltcharakteristik des Käfigs verändert. Zu diesem Zweck werden die Auswirkungen von drei unterschiedlichen Gastmolekülen auf die Ringöffnung oder den Ringschluss eines Dithienylethen (DTE)-Liganden in einem photoschaltbaren Koordinationskäfig auf DTE-Basis einander gegenübergestellt. Der Gast moduliert sowohl das Ergebnis als auch die Zeitskala der Photodynamik des Käfigs durch ein Zusammenspiel von struktureller Wechselwirkung, dem Schweratomeffekt und einer Verstärkung von Ladungstransferprozessen, die der Gast auf den photoangeregten Käfig ausübt. Der Ansatz könnte sich als nützlich erweisen, um die Anwendbarkeit von photoschaltbaren Nanocontainern und gewünschten Gastverbindungen aufeinander abzustimmen.
description: deutsche und englische Version vorhanden
Brachysyntexis tigris Kopylov 2018, sp. nov.
Creators: name: Kopylov, Dmitry S.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Anaxyelidae
Brachysyntexis
Brachysyntexis tigris

description: Brachysyntexis tigris Kopylov sp. nov.
(Figs. 2, 4B)
Etymology. The species name, a noun, is derived from the Latin ‘tigris’ (tiger) due to its striped colouration.
Material. Holotype: PIN, no. 2997/648, from Karatau (Kazakhstan), part without counterpart, imago, female. Relatively good preservation of the body; the ovipositor is distinguishable, one fore wing is preserved well, the other front wing and the hind wings are not complete; the legs and antennae are not preserved.
Description. Body light with dark mesonotum and dark transverse strips on abdomen; wing veins dark, membrane not coloured. Eye height equal to 0.5 of head height. Mesonotum without apparent sculpture, with welldeveloped longitudinal and V-shaped (scuto-scutellar) sulci and notauli, ratio of lengths of prescutum/longitudinal sulci between the prescutum and scutellum 2.0/1.0/3.7. Mesoscutellum with pointed front edge, 1.6 × as long as wide. Fore wing with costal cell very narrow; Sc not distinguishable (probably not preserved); 1-Rs straight, 1.8 × as long as 1-M; 2-M 1.2 × as long as Rs+M; 2-Rs 1.2 × as long as 1r-rs; 2r-rs 1.5 × as long as 1r-rs, issues from pterostigma at 3/5 of its length, rear edge of pterostigma slightly bent near 2r-rs; cell 1r 1.2 × as long as 2r; 2r 2.1 × as long as wide; 4+5-Rs 1.9 × as long as 3-Rs; 3+4-M 2.0 × as long as 5-M; 3r-m inclined, as long as 5-M; 2-Cu 1.6 × as long as 1-Cu; 1cu-a arched; 2cu-a straight; 3-1A 1.7 × as long as 2-1A. Hind wing with cell 1r 4.8 × as long as wide; 1-Rs 1.4 × as long as 2-Rs. Ovipositor very short, only extends slightly beyond the tip of the abdomen.
Measurements (in mm): length of body 15.0; head height 2.2; length of the fore wing 8.4, width 3.1.
Comparison. Regarding the structure of the mesonotum, the shape of pterostigma, cells 1r, 2r, 1mcu, 2+3rm, with length 5-M, inclival 3r-m, the new species is closest to B. tenebrosa (described above), from which it differs in smaller eyes, short 1-Rs, long 2-Rs in the fore wing, lighter colouration of the body, and smaller size.
description: Published as part of Kopylov, Dmitry S., 2018, Forgotten giants: new Anaxyelidae (Hymenoptera) from the Jurassic of Karatau, pp. 332-340 in Zootaxa 4514 (3) on pages 334-335, DOI: 10.11646/zootaxa.4514.3.2, http://zenodo.org/record/2608059
Additional file 1: Table S1. of Transcription analysis of neonicotinoid resistance in Mediterranean (MED) populations of B. tabaci reveal novel cytochrome P450s, but no nAChR mutations associated with the phenotype
Creators: name: Ilias, Aris
name: Lagnel, Jacques
name: Kapantaidaki, Despoina E.
name: Roditakis, Emmanouil
name: Tsigenopoulos, Costas S.
name: Vontas, John
name: Tsagkarakou, Anastasia
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Statistics summary of library reads. (DOCX 14 kb)
Hydrogen‐Bond‐Modulated Nucleofugality of SeIII Species to Enable Photoredox‐Catalytic Semipinacol Manifolds
Creators: name: Park, Sooyoung
name: Dutta, Amit K.
name: Allacher, Carina
name: Abramov, Alex
name: Dullinger, Philipp
name: Kuzmanoska, Katerina
name: Fritsch, Daniela
name: Hitzfeld, Patrick
name: Horinek, Dominik
name: Rehbein, Julia
name: Nuernberger, Patrick
name: Gschwind, Ruth Maria
name: Breder, Alexander
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: CENTER-DOT-OP; SCALAR COUPLINGS; ELECTRON-TRANSFER; RING ENLARGEMENT; BETA; REARRANGEMENT; EXPANSION; RADICALS; KETONES; Hydrogen-Bonds; Nucleofugality; Photoredox-Catalysis; Rearrangements; Selenium(III)
subject: 540 Chemie

description: Chemical bond activations mediated by H-bond interactions involving highly electronegative elements such as nitrogen and oxygen are powerful tactics in modern catalysis research. On the contrary, kindred catalytic regimes in which heavier, less electronegative elements such as selenium engage in H-bond interactions to co-activate C-Se sigma-bonds under oxidative conditions are elusive. Traditional strategies to enhance the nucleofugality of selenium residues predicate on the oxidative addition of electrophiles onto Se-II-centers, which entails the elimination of the resulting Se-IV moieties. Catalytic procedures in which Se-IV nucleofuges are substituted rather than eliminated are very rare and, so far, not applicable to carbon-carbon bond formations. In this study, we introduce an unprecedented combination of O-H center dot center dot center dot Se H-bond interactions and single electron oxidation to catalytically generate Se-III nucleofuges that allow for the formation of new C-C sigma-bonds by means of a type I semipinacol process in high yields and excellent selectivity.