cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Intergenerational effects of violence on women’s perinatal wellbeing and infant health outcomes: evidence from a birth cohort study in Central Vietnam
Creators: name: Do, Huyen Phuc
name: Baker, Philip R. A.
name: Van Vo, Thang
name: Murray, Aja
name: Murray, Linda
name: Valdebenito, Sara
name: Eisner, Manuel
name: Tran, Bach Xuan
name: Dunne, Michael P.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Research
Pregnant women
Prenatal intimate partner violence
Mediation pathway
Violent victimization
Childhood maltreatment

description: Abstract: Background: Girls exposed to violence have a high risk of being victimized as adults and are more likely than non-abused women to have children who are treated violently. This intergenerational transmission may be especially serious when women suffer violence during pregnancy and early motherhood, as it impairs maternal wellbeing and infant health and development. This study examined the intergenerational effects of being exposed to childhood maltreatment (CM) and prenatal intimate partner violence (p-IPV) on perinatal mental distress and birth outcomes in central Vietnam. Methods: A birth cohort study in Hue City, Vietnam was conducted with 150 women in the third trimester of pregnancy (Wave 1) and 3 months after childbirth (Wave 2). Using multivariable logistic regression models, augmented inverse-probability-weighted estimators and structural equation modelling (SEM), we analyzed a theoretical model by evaluating adjusted risk differences and pathways between CM, p-IPV and subsequent perinatal adversity and indicators of infant health problems. Results: One in two pregnant women experienced at least one form of CM (55.03%) and one in ten pregnant women experienced both CM and p-IPV (10.67%). Mothers who experienced p-IPV or witnessed IPV as a child were approximately twice as likely to experience poor mental health during pregnancy [ARR 1.94, 95% CI (1.20–3.15)]. Infants had a two-fold higher risk of adverse birth outcomes (low birth weight, preterm birth, admission to neonatal intensive care) [ARR 2.45 95% CI (1.42, 4.25)] if their mothers experienced any form of p-IPV, with greater risk if their mothers were exposed to both CM and p-IPV [ARR 3.45 95% CI (1.40, 8.53)]. Notably, significant pathways to p-IPV were found via adverse childhood experience (ACE) events (β = 0.13), neighborhood disorder (β = 0.14) and partner support (β = − 1.3). Conclusion: These results emphasize the detrimental and prolonged nature of the effect of violence during childhood and pregnancy. Exposure to childhood maltreatment and violence during pregnancy increases the risk of maternal mental health difficulties and adverse birth outcomes. Antenatal care systems need to be responsive to women’s previous experiences of violence and maternal mental health. The significant protective role of partner support and social support should also be considered when designing tailored interventions to address violence during pregnancy.
Empirische Untersuchung der agilen Softwareentwicklung
Creators: name: Höfer, Andreas
Publisher: name: Karlsruhe
Year: 2011

description: Die Entwicklungsmethoden der Paarprogrammierung und der testgetriebenen Entwicklung gerieten bereits 1990er Jahren in den Fokus der Forschung. Dennoch sind zu diesen beiden Entwicklungsmethoden längst nicht alle Fragen beantwortet. In dieser Arbeit werden drei noch zu beantwortende Fragen bezüglich dieser Entwicklungsmethoden identifiziert und es wird mit drei entsprechenden Studien versucht, diese Fragen zu beantworten.
The Size Distribution of the Neptune Trojans and the Missing Intermediate Sized Planetesimals
Creators: name: Sheppard, Scott S.
name: Trujillo, Chadwick A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present an ultra-deep survey for Neptune Trojans using the Subaru 8.2-m and Magellan 6.5-m telescopes. The survey reached a 50% detection efficiency in the R-band at 25.7 magnitudes and covered 49 square degrees of sky. This depth corresponds to Neptune Trojans that are about 16 km in radius (assuming an albedo of 0.05). A paucity of smaller Neptune Trojans (radii < 45 km) compared to larger ones was found. The brightest Neptune Trojans appear to follow a steep power-law slope (q = 5+-1) similar to the brightest objects in the other known stable reservoirs such as the Kuiper Belt, Jupiter Trojans and main belt asteroids. We find a roll-over for the Neptune Trojans that occurs around a radii of r=45+-10 km (23.5+-0.3 mags), which is also very similar to the other stable reservoirs. All the observed stable regions in the the solar system show evidence for Missing Intermediate Sized Planetesimals (MISPs). This indicates a primordial and not collisional origin, which suggests planetesimal formation proceeded directly from small to large objects. The scarcity of intermediate and smaller sized Neptune Trojans may limit them as being a strong source for the short period comets.
description: Accepted for publication in Astrophysical Journal Letters
Work and Health Needs of Individuals with Unstable or Lack of Housing
Creators: name: Madigan, Dana
Publisher: name: University of Illinois at Chicago
Year: 2020
Subjects: Uncategorized

description: The bidirectional link between work and health is well established and working towards mitigating disparities in these areas could have substantial impacts on the lives of those that are deeply impacted by poor health and a lack of work. The specific aims of this project were to (1) describe health care utilization of individuals with a lack of housing or affected by homelessness using the Illinois Hospital Discharge database, (2) assess chiropractic interns’ attitudes and behaviors towards occupational history taking at a clinic serving a population affected by unstable or a lack of housing and behavior changes following occupational health assessment training, and (3) evaluate needs for a comprehensive return to work program among residents of a residential work rehabilitation program for individuals with unstable or lack of housing by assessing past, present and future employment needs and expectations within this vulnerable population. These projects developed reliable tools and baseline data that can be used to further explore these issues. The results, added to the growing body of literature on these topics, can be applied to inform the design of comprehensive and collaborative programs to address the intersection of health and work in those without stable housing, acknowledging the protective effects of employment on securing and maintaining stable housing.
Cortical auditory evoked potentials to estimate gap-detection thresholds in adults
Creators: name: Angel, Rebecca
Publisher: name: University of British Columbia
Year: 2016

description: Temporal resolution is the ability of the auditory system to detect small changes over time and is an important component for the detection and decoding of speech by the central auditory nervous system. Temporal resolution is most often measured by asking a person to detect small gaps between sounds, known as behavioural gap-detection tests. However, certain populations may be unable or unwilling to respond reliably due to perceptual or cognitive deficits, or in medico-legal compensation cases. There are limitations to behavioural gap-detection measures because they cannot separate cognitive from perceptual deficits. The present study utilized electrophysiological gap-detection measures as a means of objectively estimating behavioural gap-detection thresholds. Cortical auditory evoked potentials (CAEPs) are neural responses to changes in sound, duration, and frequency that can be measured from the scalp. The specific aim of this study was to collect adult normative data for CAEP gap-detection thresholds to examine if CAEPs could accurately estimate behavioural gap-detection thresholds. Gap-evoked CAEPs could be recorded in participants who were awake and passively listening and could estimate temporal resolution without the need for a participant’s cooperation or attention. The results showed that there was a significant N1-P2 response to gaps at ≥ 4 ms, with 85% of participants having a response to a 10 ms gap. Additionally, the electrophysiological mean gap-detection threshold was within 1 ms of behavioral mean gap-detection threshold. This demonstrated that gap-evoked CAEPs can accurately estimate behavioural gap-detection thresholds in a normal hearing adult population.
Community-based Enterprises in Italy: Definition and Governance Models
Creators: name: Bandini, Federica
name: Renato, Medei
name: Claudio, Travaglini
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2014
Subjects: SECS-P/07 Economia aziendale

description: In recent years, a new form of co-operative business is taking shape in Italy: the community-based enterprise, a community acting collectively at both management and business level, to pursue common goals. Community-based enterprises grow on a system of networks of free relationships among the members of a local community, with a high degree of reciprocity; when individuals work together in a business systems, relationships become social relationships. The complex of the community members’ relationships, objectives and expectations towards the company reflects necessarily on governance models that should follow a multistakeholder pattern. Multistakeholdership implies a direct and active participation of subjects bearing conflicting interests in the decisional process. This paper describes community-based enterprises in Italy, draws their governance models, and emphasizes how the passage from opening to different stakeholders to implementation of multistakeholder governance is very slow and difficult to put into practice.
On the importance of Task 1 and error performance measures in PRP dual-task studies
Creators: name: Strobach, Tilo
name: Schütz, Anja
name: Schubert, Torsten
Publisher: name: Humboldt-Universität zu Berlin
Year: 2015
Subjects: subject: PRP
subject: dual tasks
subject: capacity limitation
subject: central bottleneck theory
subject: reaction times
subject: error data
subject: 150 Psychologie

description: The psychological refractory period (PRP) paradigm is a dominant research tool in the literature on dual-task performance. In this paradigm a first and second component task (i.e., Task 1 and Task 2) are presented with variable stimulus onset asynchronies (SOAs) and priority to perform Task 1. The main indicator of dual-task impairment in PRP situations is an increasing Task 2-RT with decreasing SOAs. This impairment is typically explained with some task components being processed strictly sequentially in the context of the prominent central bottleneck theory. This assumption could implicitly suggest that processes of Task 1 are unaffected by Task 2 and bottleneck processing, i.e., decreasing SOAs do not increase reaction times (RTs) and error rates of the first task. The aim of the present review is to assess whether PRP dual-task studies included both RT and error data presentations and statistical analyses and whether studies including both data types (i.e., RTs and error rates) show data consistent with this assumption (i.e., decreasing SOAs and unaffected RTs and/or error rates in Task 1). This review demonstrates that, in contrast to RT presentations and analyses, error data is underrepresented in a substantial number of studies. Furthermore, a substantial number of studies with RT and error data showed a statistically significant impairment of Task 1 performance with decreasing SOA. Thus, these studies produced data that is not primarily consistent with the strong assumption that processes of Task 1 are unaffected by Task 2 and bottleneck processing in the context of PRP dual-task situations; this calls for a more careful report and analysis of Task 1 performance in PRP studies and for a more careful consideration of theories proposing additions to the bottleneck assumption, which are sufficiently general to explain Task 1 and Task 2 effects.
Concept and Design of a Hand-held Mobile Robot System for Craniotomy
Creators: name: Kane, Gavin J.
Publisher: name: Karlsruhe
Year: 2011
Subjects: Medical Robot
Craniotomy
Wheeled Robot
Craniosynostosis

description: This work demonstrates a highly intuitive robot for Surgical Craniotomy Procedures. Utilising a wheeled hand-held robot, to navigate the Craniotomy Drill over a patient's skull, the system does not remove the surgeons from the procedure, but supports them during this critical phase of the operation.
A Distinctive Disk-Jet Coupling in the Seyfert-1 AGN NGC 4051
Creators: name: King, Ashley L.
name: Miller, Jon M.
name: Cackett, Edward M.
name: Fabian, Andy C.
name: Markoff, Sera
name: Nowak, Michael A.
name: Rupen, Michael
name: Gultekin, Kayhan
name: Reynolds, Mark T.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We report on the results of a simultaneous monitoring campaign employing eight Chandra X-ray (0.5-10 keV) and six VLA/EVLA (8.4 GHz) radio observations of NGC 4051 over seven months. Evidence for compact jets is observed in the 8.4 GHz radio band; This builds on mounting evidence that jet production may be prevalent even in radio-quiet Seyferts. Assuming comparatively negligible local diffuse emission in the nucleus, the results also demonstrate an inverse correlation of L_radio proportional to L_X-ray ^(-0.72+/-0.04) . Current research linking the mass of supermassive black holes and stellar-mass black holes in the "low/hard" state to X-ray luminosities and radio luminosities suggest a "fundamental plane of accretion onto black holes" that has a positive correlation of L_radio proportional to L_X-ray^(0.67+/-0.12) . Our simultaneous results differ from this relation by more than 11 sigma, indicating that a separate mode of accretion and ejection may operate in this system. A review of the literature shows that the inverse correlation seen in NGC 4051 is seen in three other black hole systems, all of which accrete at near 10% of their Eddington luminosity, perhaps suggesting a distinct mode of disk-jet coupling at high Eddington fractions. We discuss our results in the context of disk and jets in black holes and accretion across the black hole mass scale.
description: 12 pages, 9 figures
Plasmons in nanostructures with applications to metamaterial science
Creators: name: Bernadotte, Stephan
Publisher: name: Karlsruhe
Year: 2011

description: A numerical and an analytical model allowing the calculation of plasmonic resonances in finite systems are presented and compared. Both models are applied to provide a quantum-mechanical study of the resonances of a split-ring resonator serving as a building block in metamaterial science. In order to describe a macroscopic medium, the interaction among the rings is analyzed and a macroscopic medium theory was developed. Guidelines for the construction of negative index materials are given.
Tail state mediated conduction in zinc tin oxide thinfilm phototransistors under below bandgap optical excitation
Creators: name: Dhara, Soumen
name: Niang, Kham M.
name: Flewitt, Andrew J.
name: Nathan, Arokia
name: Lynch, Stephen A.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Article
/639/301/1005
/639/301/1005/1007
/639/624/399
article

description: Abstract: We report on the appearance of a strong persistent photoconductivity (PPC) and conductor-like behaviour in zinc tin oxide (ZTO) thinfilm phototransistors. The active ZTO channel layer was prepared by remote plasma reactive sputtering and possesses an amorphous structure. Under sub-bandgap excitation of ZTO with UV light, the photocurrent reaches as high as ~ 10−4 A (a photo-to-dark current ratio of ~ 107) and remains close to this high value after switching off the light. During this time, the ZTO TFT exhibits strong PPC with long-lasting recovery time, which leads the appearance of the conductor-like behaviour in ZTO semiconductor. In the present case, the conductivity changes over six orders of magnitude, from ~ 10−7 to 0.92/Ω/cm. After UV exposure, the ZTO compound can potentially remain in the conducting state for up to a month. The underlying physics of the observed PPC effect is investigated by studying defects (deep states and tail states) by employing a discharge current analysis (DCA) technique. Findings from the DCA study reveal direct evidence for the involvement of sub-bandgap tail states of the ZTO in the strong PPC, while deep states contribute to mild PPC.
Generation of Surface Nanotubes on Titanium Kirschner Wire for the Enhanced Release of Antibacterial Drug
Creators: name: Girotto, Lorenzo
Publisher: name: University of Illinois at Chicago
Year: 2020
Subjects: Uncategorized

description: Titanium and its alloys are widely used in medical applications for their excellent properties such as biocompatibility, low toxicity, high chemical stability, good fatigue strength, and resistance to corrosion. Unfortunately, those properties do not always prevent the human organism to attack and isolate Ti implants causing explantation and, therefore high costs and inconvenience for the patient. That is why a surface modification is often performed to improve the integration with the tissues without affecting the bulk properties of the material. Lately, researchers focused their attention on the functionalization of the surface at the nanoscale, which has proven to offer a wide range of applications in many different fields. The goal of this study was to obtain titanium dioxide nanotubes (TNTs) on the surface of titanium implants by anodization. Furthermore, their properties were exploited to load vancomycin in a solution for a drug release test in a potential antibacterial application of the implant in vivo. The anodization was performed in an ethylene glycol-based solution (98 vol%) containing 0.3 wt% ammonium fluoride (NH4F) and 2 vol% deionized water. The reaction took place for 60 min at a constant voltage of 50 V with a sweep rate of 1 V/s. The resulting nanotubes were approximately 80 nm in diameter and hypothetically 2 μm long. The length was solely estimated since we could not obtain cross-sectional images. Compared to a smooth implant, the surface area of the anodized wire increased by 50 times. Raman spectroscopy did not appear to be a feasible alternative for quantitative analysis of antibiotics in solution. Hence, we opted for ultraviolet-visible (UV-Vis) spectroscopy. The vancomycin solution was loaded in the implant and a release test was performed. The anodized wires showed to release nearly 80% more antibiotic after 2 hours compared to smooth titanium.
Cells of the adult human heart
Creators: name: Litviňuková, Monika
name: Talavera-López, Carlos
name: Maatz, Henrike
name: Reichart, Daniel
name: Worth, Catherine L.
name: Lindberg, Eric L.
name: Kanda, Masatoshi
name: Polanski, Krzysztof
name: Heinig, Matthias
name: Lee, Michael
name: Nadelmann, Emily R.
name: Roberts, Kenny
name: Tuck, Liz
name: Fasouli, Eirini S.
name: DeLaughter, Daniel M.
name: McDonough, Barbara
name: Wakimoto, Hiroko
name: Gorham, Joshua M.
name: Samari, Sara
name: Mahbubani, Krishnaa T.
name: Saeb-Parsy, Kourosh
name: Patone, Giannino
name: Boyle, Joseph J.
name: Zhang, Hongbo
name: Zhang, Hao
name: Viveiros, Anissa
name: Oudit, Gavin Y.
name: Bayraktar, Omer Ali
name: Seidman, J. G.
name: Seidman, Christine E.
name: Noseda, Michela
name: Hubner, Norbert
name: Teichmann, Sarah A.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/208/199
/692/308/2056
/38/91
/45/62
/14/32
/13
article

description: Abstract: Cardiovascular disease is the leading cause of death worldwide. Advanced insights into disease mechanisms and therapeutic strategies require a deeper understanding of the molecular processes involved in the healthy heart. Knowledge of the full repertoire of cardiac cells and their gene expression profiles is a fundamental first step in this endeavour. Here, using state-of-the-art analyses of large-scale single-cell and single-nucleus transcriptomes, we characterize six anatomical adult heart regions. Our results highlight the cellular heterogeneity of cardiomyocytes, pericytes and fibroblasts, and reveal distinct atrial and ventricular subsets of cells with diverse developmental origins and specialized properties. We define the complexity of the cardiac vasculature and its changes along the arterio-venous axis. In the immune compartment, we identify cardiac-resident macrophages with inflammatory and protective transcriptional signatures. Furthermore, analyses of cell-to-cell interactions highlight different networks of macrophages, fibroblasts and cardiomyocytes between atria and ventricles that are distinct from those of skeletal muscle. Our human cardiac cell atlas improves our understanding of the human heart and provides a valuable reference for future studies.
Additional file 1 of 1L NER1006 can improve rates of adequate and high-quality bowel cleansing in the right colon: a post hoc analysis of two randomised clinical trials
Creators: name: Manning, Jonathan
name: Halonen, Juha
name: Cheriyamkunnel, Sandra Jose
name: Álvarez-González, Marco Antonio
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Product formulations of NER1006, OSS and 2LPEG.
title: MasAzil_Piette_OsHumainsAzilien
Creators: name: Robin Andrews
name: DAVID, Éva
name: AnTET - ArScAn UMR 7041
Publisher: name: Archeovision
Year: 2022
Subjects: subject: Azilien
subject: os humain
subject: Épipaléolithique

description: 10 os humains impactés, pigmentés et lustrés provenant des fouilles d'Edouard Piette dans la grotte du Mas d'Azil (Ariège) fouillée entre 1887 et 1890 (niveau azilien) et déposés au Musée d'Archéologie nationale (MAN - Salle Piette)
description: 11 scans artec space spider ; 22 fichiers; 1,59 GB
The Human and Mouse Islet Peptidome: Effects of Obesity and Type 2 Diabetes, and Assessment of Intraislet Production of Glucagon-like Peptide-1.
Creators: name: Galvin, Sam G
name: Kay, Richard G
name: Foreman, Rachel
name: Larraufie, Pierre
name: Meek, Claire L
name: Biggs, Emma
name: Ravn, Peter
name: Jermutus, Lutz
name: Reimann, Frank
name: Gribble, Fiona M
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Insulin
Glucagon
Mass spectrometry
Type 2 diabetes
pancreatic islets
Peptidomics

description: To characterize the impact of metabolic disease on the peptidome of human and mouse pancreatic islets, LC-MS was used to analyze extracts of human and mouse islets, purified mouse alpha, beta, and delta cells, supernatants from mouse islet incubations, and plasma from patients with type 2 diabetes. Islets were obtained from healthy and type 2 diabetic human donors, and mice on chow or high fat diet. All major islet hormones were detected in lysed islets as well as numerous peptides from vesicular proteins including granins and processing enzymes. Glucose-dependent insulinotropic peptide (GIP) was not detectable. High fat diet modestly increased islet content of proinsulin-derived peptides in mice. Human diabetic islets contained increased content of proglucagon-derived peptides at the expense of insulin, but no evident prohormone processing defects. Diabetic plasma, however, contained increased ratios of proinsulin and des-31,32-proinsulin to insulin. Active GLP-1 was detectable in human and mouse islets but 100-1000-fold less abundant than glucagon. LC-MS offers advantages over antibody-based approaches for identifying exact peptide sequences, and revealed a shift toward islet insulin production in high fat fed mice, and toward proglucagon production in type 2 diabetes, with no evidence of systematic defective prohormone processing.
title: Modélisation 3D (CityGml) du tissus urbain de 1796 de Charleville
Creators: name: Bruno Hilaire
name: Rassat, Sylvain
name: Laboratoire Méditerranéen de Préhistoire Europe Afrique
Publisher: name: Archeovision
Year: 2021

description: Numérisation en 3D exhaustive (LOD 1) à partir des données numérisées issues du plan 'Legendre' (1796) conservé au musée de l'Ardenne (© musée de l'Ardenne) maquette 3D consultable en ligne : https://cesium.cstb.fr/Apps/cnrs/MN_Charleville3D.html
L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion.
Creators: name: Kuhre, Rune E
name: Modvig, Ida M
name: Jepsen, Sara L
name: Kizilkaya, Hüsün S
name: Bæch-Laursen, Cecilie
name: Smith, Christopher A
name: Reimann, Frank
name: Gribble, Fiona M
name: Rosenkilde, Mette M
name: Holst, Jens J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: alpha-MSH
Melanocortin
L-cells
Glucagon-like Peptide-1 Secretion
Melanocortin-4-receptor

description: The molecular sensors underlying nutrient-stimulated GLP-1 secretion are currently being investigated. Peripheral administration of melanocortin-4 receptor (MC4R) agonists have been reported to increase GLP-1 plasma concentrations in mice and humans but it is unknown whether this effect results from a direct effect on the GLP-1 secreting L-cells in the intestine, from other effects in the intestine or from extra-intestinal effects. We investigated L-cell expression of MC4R in mouse and human L-cells by reanalyzing publicly available RNA sequencing databases (mouse and human) and by RT-qPCR (mouse), and assessed whether administration of MC4R agonists to a physiologically relevant gut model, isolated perfused mouse and rat small intestine, would stimulate GLP-1 secretion or potentiate glucose-stimulated secretion. L-cell MC4R expression was low in mouse duodenum and hardly detectable in the ileum and MC4R expression was hardly detectable in human L-cells. In isolated perfused mouse and rat intestine, neither intra-luminal nor intra-arterial administration of NDP-alpha-MSH, a potent MC4R agonist, had any effect on GLP-1 secretion (P ≥0.98, n = 5-6) from the upper or lower-half of the small intestine in mice or in the lower half in rats. Furthermore, HS014-an often used MC4R antagonist, which we found to be a partial agonist-did not affect the glucose-induced GLP-1 response in the rat, P = 0.62, n = 6). Studies on transfected COS7-cells confirmed bioactivity of the used compounds and that concentrations employed were well within in the effective range. Our combined data therefore suggest that MC4R-activated GLP-1 secretion in rodents either exclusively occurs in the colon or involves extra-intestinal signaling.
An elementary stringy estimate of transport coefficients of large temperature QCD
Creators: name: Bigazzi, Francesco
name: Cotrone, Aldo L.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Modeling QCD at large temperature with a simple holographic five dimensional theory encoding minimal breaking of conformality, allows for the calculation of all the transport coefficients, up to second order, in terms of a single parameter. In particular, the shear and bulk relaxation times are provided. The result follows by deforming the AdS background with a scalar dual to a marginally relevant operator, at leading order in the deformation parameter.
description: 11 pages; v2: comments and references added
An oomycete effector subverts host vesicle trafficking to channel starvation-induced autophagy to the pathogen interface.
Creators: name: Pandey, Pooja
name: Leary, Alexandre Y
name: Tumtas, Yasin
name: Savage, Zachary
name: Dagvadorj, Bayantes
name: Duggan, Cian
name: Yuen, Enoch Lh
name: Sanguankiattichai, Nattapong
name: Tan, Emily
name: Khandare, Virendrasinh
name: Connerton, Amber J
name: Yunusov, Temur
name: Madalinski, Mathias
name: Mirkin, Federico Gabriel
name: Schornack, Sebastian
name: Dagdas, Yasin
name: Kamoun, Sophien
name: Bozkurt, Tolga O
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: subject: Haustorium
subject: Phytophthora infestans
subject: Nicotiana benthamiana
subject: Autophagy
subject: Plant Biology
subject: FOS: Biological sciences
subject: Autophagy Inhibition

description: Eukaryotic cells deploy autophagy to eliminate invading microbes. In turn, pathogens have evolved effector proteins to counteract antimicrobial autophagy. How adapted pathogens co-opt autophagy for their own benefit is poorly understood. The Irish famine pathogen Phytophthora infestans secretes the effector protein PexRD54 that selectively activates an unknown plant autophagy pathway that antagonizes antimicrobial autophagy at the pathogen interface. Here, we show that PexRD54 induces autophagosome formation by bridging vesicles decorated by the small GTPase Rab8a with autophagic compartments labeled by the core autophagy protein ATG8CL. Rab8a is required for pathogen-triggered and starvation-induced but not antimicrobial autophagy, revealing specific trafficking pathways underpin selective autophagy. By subverting Rab8a-mediated vesicle trafficking, PexRD54 utilizes lipid droplets to facilitate biogenesis of autophagosomes diverted to pathogen feeding sites. Altogether, we show that PexRD54 mimics starvation-induced autophagy to subvert endomembrane trafficking at the host-pathogen interface, revealing how effectors bridge distinct host compartments to expedite colonization.
Short-term exposure of dairy cows to pyrrolizidine alkaloids from tansy ragwort (Jacobaea vulgaris Gaertn.): effects on health and performance
Creators: name: Knoop, Kirsten
name: Knappstein, Karin
name: Kaltner, Florian
name: Gabler, Angelika Miriam
name: Taenzer, Julian
name: These, Anja
name: Kersten, Susanne
name: Meyer, Ulrich
name: Frahm, Jana
name: Kluess, Jeannette
name: Hüther, Liane
name: Gottschalk, Christoph
name: Knudsen, Knud Erik Bach
name: Saltzmann, Janine
name: Dänicke, Sven
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Medicine
Cell Biology
Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The increasing spread of ragworts is observed with concern. Ragworts like tansy ragwort (Jacobaea vulgaris Gaertn.) or marsh ragwort (J. aquatica) contain pyrrolizidine alkaloids (PA) which may induce hepatotoxic effects. Grazing animals usually avoid ragworts if their pasture management is appropriate. Preserved feed prepared from ragworts contaminated meadows may, however, lead to a significant exposure to PA. Previous studies on toxicity of PA for dairy cows revealed inconsistent results due to feeding ragwort plant material which was associated with heterogeneous PA exposure and thus failed to conclusively deduce critical PA doses. Therefore, the aim of the present study was to expose dairy cows (n = 4 per group) in a short-term scenario for 28 days with increasing PA doses (PA1: 0.47 mg PA/kg body weight (BW)/day (d); PA2: 0.95 mg PA/kg BW/d; PA3: 1.91 mg PA/kg BW/d) via oral administration by gavage of a defined PA-extract. While group PA3 was dosed with the PA-extract alone, groups PA2 and PA1 received PA-extracts blended in similar volumes with molasses to provide comparable amounts of sugar. Additionally, two control groups were treated either with water (CONWater) or with molasses (CONMolasses) to assess the effects of sugar without PA interference. While clinical traits including dry matter intake, milking performance, rectal body temperature, ruminal activity and body condition score (BCS) were not influenced by PA exposure, activities of enzymes indicative for liver damages, such as gamma-glutamyltransferase (GGT), aspartate aminotransferase (AST) and glutamate dehydrogenase (GLDH), increased significantly over time at an exposure of 1.91 mg total PA/kg BW/d.
PI3K in T Cell Adhesion and Trafficking.
Creators: name: Johansen, Kristoffer H
name: Golec, Dominic P
name: Thomsen, Julie H
name: Schwartzberg, Pamela L
name: Okkenhaug, Klaus
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Integrin
PI3K
CD62L
Trafficking
adhesion
CCR7
Lfa-1

description: PI3K signalling is required for activation, differentiation, and trafficking of T cells. PI3Kδ, the dominant PI3K isoform in T cells, has been extensively characterised using PI3Kδ mutant mouse models and PI3K inhibitors. Furthermore, characterisation of patients with Activated PI3K Delta Syndrome (APDS) and mouse models with hyperactive PI3Kδ have shed light on how increased PI3Kδ activity affects T cell functions. An important function of PI3Kδ is that it acts downstream of TCR stimulation to activate the major T cell integrin, LFA-1, which controls transendothelial migration of T cells as well as their interaction with antigen-presenting cells. PI3Kδ also suppresses the cell surface expression of CD62L and CCR7 which controls the migration of T cells across high endothelial venules in the lymph nodes and S1PR1 which controls lymph node egress. Therefore, PI3Kδ can control both entry and exit of T cells from lymph nodes as well as the recruitment to and retention of T cells within inflamed tissues. This review will focus on the regulation of adhesion receptors by PI3Kδ and how this contributes to T cell trafficking and localisation. These findings are relevant for our understanding of how PI3Kδ inhibitors may affect T cell redistribution and function.
Residential Location Choice and Travel Behavior of Young adults: Coming-to-the-city and Multimodality
Creators: name: Jaeyong Shin
Publisher: name: University of Illinois at Chicago
Year: 2020
Subjects: Uncategorized

description: Young adults have received increasing attention since the late 2000s due to their different residential choice and travel behavior when compared to prior generations and older cohorts. Young adults drove fewer miles, owned fewer cars, and used non-automobile modes (public transit, walk, or bicycle modes) at a higher rate. Further, young adults showed a higher preference for living in cities. A higher proportion of young adults lived in central areas in cities in the 2010s than the 2000s and as compared to other age groups. This dissertation examines these two choice behaviors of young adults to fill gaps in literature through three independent research. The ﬁrst research examines residential location trends of young adults and older adults in the most populous 50 U.S. cities and important factors in their decisions. The second research examines differences in residential location choice within young adults using national-level longitudinal data. Last, the research examines the relationship between location choice and travel behavior using travel survey data in the Seattle metropolitan area. The main ﬁndings from the dissertation can be summarized as follows: 1) Young adults have come to U.S. cities since 2000 and at higher rate since 2010, while older age groups have left cities. Urban industry (especially high-income jobs), transportation, and amenities are important factors in the location preference of young adults. 2) There is also a diversity in residential location preference within the young adult cohort that depends on their lifecycle stage and socio-demographic characteristics as well as a period (the 2000s vs. 2010s). 3) There are complex relationships between being a young adult, location choice, and travel behavior. One of the findings is that being a young adult has no direct effects on mode choice and travel distance. Its effects are only indirect through the residential location and auto ownership decisions. Taken together, these ﬁndings suggest that if conditions in cities don’t change in ways that make them attractive to the life cycle of young adults, it is very likely that their behaviors will become like that of prior generations —suburbs, more cars, and more driving. Young adults, however, are showing interests in living in cities, it is a role of planners and policy makers to encourage them to stay as they age and to attract even more of them.
Search for brown-dwarf companions of stars
Creators: name: Sahlmann, Johannes
name: Segransan, Damien
name: Queloz, Didier
name: Udry, Stephane
name: Santos, Nuno C.
name: Marmier, Maxime
name: Mayor, Michel
name: Naef, Dominique
name: Pepe, Francesco
name: Zucker, Shay
Publisher: name: arXiv
Year: 2010
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The discovery of 9 new brown-dwarf candidates orbiting stars in the CORALIE and HARPS radial-velocity surveys is reported. New CORALIE radial velocities yielding accurate orbits of 6 previously-known hosts of potential brown-dwarf companions are presented. Including targets selected from the literature, 33 hosts of potential brown-dwarf companions are examined. Employing innovative methods, we use the new reduction of the Hipparcos data to fully characterise the astrometric orbits of 6 objects, revealing M-dwarf companions with masses between 90 M_Jup and 0.52 M_Sun. Additionally, the masses of two companions can be restricted to the stellar domain. The companion to HD 137510 is found to be a brown dwarf. At 95 % confidence, the companion of HD 190228 is also a brown dwarf. The remaining 23 companions persist as brown-dwarf candidates. Based on the CORALIE planet-search sample, we obtain an upper limit of 0.6 % for the frequency of brown-dwarf companions around Sun-like stars. We find that the companion-mass distribution function is rising at the lower end of the brown-dwarf mass range, suggesting that in fact we are detecting the high-mass tail of the planetary distribution.
description: 24 pages, 21 figures, 10 tables. Accepted for publication in Astronomy and Astrophysics. Abridged abstract
Localised zero-energy modes in the Kitaev model with vacancy-disorder
Creators: name: G., Santhosh
name: Sreenath, V.
name: Lakshminarayan, Arul
name: Narayanan, Rajesh
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We study the effects of vacancy disorder on the Kitaev model defined on a hexagonal lattice. We show that the vacancy disorder induces a zero-mode that is localized at the defect site. We derive analytical forms for these localized wave functions in both the gapped and gapless phases of the Kitaev model. We conjecture that the vacancy disorder can be utilized as a probe of the quantum phase transition (from the gapped to gapless phases) in this model. The behavior of the Inverse Participation Ratio (IPR) in the gapless phase and across the transition is also studied numerically. Comments are made about the behavior of site-site entanglement in the single particle states for the case of a single vacancy.
description: 8 pages, 3 figures. Version with references corrected
title: IMPERATRICE 2019
Creators: name: Sorin, Sabine
name: CEPAM UMR 7264
Publisher: name: Archeovision
Year: 2021

description: Relevés par photogrammétrie des niveaux d'occupations - Note : IMP 2019 4 fichiers ply - 00_IMP2019_total_fin_fouille  - IMP2019_Foyer_M12_PH1 - IMP2019_Foyer_M12_PH4 - IMP2019_sondage_L16_L14 5 ortho-images jpg  Tiff 1 livrable pdf
title: IMPERATRICE 2018
Creators: name: Sorin, Sabine
name: CEPAM UMR 7264
Publisher: name: Archeovision
Year: 2021

description: Relevés par photogrammétrie des niveaux d'occupations - Note : 17 fichiers ply - 00_IMP2018_total_fin_fouille - IMP2018_Coupe_L12_L13 - IMP2018_Coupe_L12_L13 - IMP_2018_Coupe_L13Nord - IMP2018_Coupe_Berne_N14_N13 - IMP2018_Coupe_I13_J13_Ouest - IMP2018_Coupe_K11_K12 - IMP2018_Coupe_L14_Nord - IMP2018_Fond_sud_Abri - IMP2018_Foyer_V13_Decap1 - IMP2018_Foyer_V13_Decap2 - IMP2018_I13_J13 - IMP2018_J12_J13 - IMP2018_L12_Schiste_ss_Bloc - IMP2018_Zone_Cendreuse_SS_Bloc - IMP2018_Zone_Cendreuse_SS_Bloc2 - IMP2018_Zone_SS_Bloc_K12_L12
Deliverable: Prototype Remote Desktop and Jupyter Service (4.2)
Creators: name: Greenwood, Lottie
name: Hall, Jamie
name: Fangohr, Hans
name: Kluyver, Thomas
name: Rosca, Robert
Publisher: name: Zenodo
Year: 2020
Subjects: PaNOSC
Jupyter
Remote desktop

description: This document provides the context of remote data analysis services for the photon and neutron science communities and comments on the status of service provision, user experience and deployment/harmonization aspects across the PaNOSC facilities.
title: IMPERATRICE 2016
Creators: name: Sorin, Sabine
name: CEPAM UMR 7264
Publisher: name: Archeovision
Year: 2021

description: Relevés par photogrammétrie des niveaux d'occupations - Note : IMP 2016 6 fichiers ply  1 obj : - 00_IMP2016_total_fin_de_fouille - IMP2016_Coupe_L15_L16 - IMP2016_coupe_ss_blocs - IMP2016_coupeL - IMP2016_coupeS - IMP2016_Tranche_QR - IMP2016_US102_ss_Bloc 3 livrables PDF 11 livrables jpg
Electronic Correlation and Transport Properties of Nuclear Fuel Materials
Creators: name: Yin, Quan
name: Kutepov, Andrey
name: Haule, Kristjan
name: Kotliar, Gabriel
name: Savrasov, Sergey Y.
name: Pickett, Warren E.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Actinide elements, such as uranium and plutonium, and their compounds are best known as nuclear materials. When engineering optimal fuel materials for nuclear power, important thermophysical properties to be considered are melting point and thermal conductivity. Understanding the physics underlying transport phenomena due to electrons and lattice vibrations in actinide systems is a crucial step toward the design of better fuels. Using first principle LDA+DMFT method, we conduct a systematic study on the correlated electronic structures and transport properties of select actinide carbides, nitrides, and oxides, many of which are nuclear fuel materials. We find that different mechanisms, electrons--electron and electron--phonon interactions, are responsible for the transport in the uranium nitride and carbide, the best two fuel materials due to their excellent thermophysical properties. Our findings allow us to make predictions on how to improve their thermal conductivities.
description: Main article: 5 pages, 3 figures. Supplementary info: 2 pages, 1 figure
title: IMPERATRICE 2017
Creators: name: Sorin, Sabine
name: CEPAM UMR 7264
Publisher: name: Archeovision
Year: 2021

description: Relevés par photogrammétrie des niveaux d'occupations - Note : IMP 2017 13 fichiers .fls 8 fichiers .ply - 00_IMP2017_total_fin_fouille_paroie - IMP2017_coupe_O13 - IMP2017_Foyer_K12 - IMP2017_Foyer_V13 - IMP2017_Foyer_V13_nvx1 - IMP2017_K11 - IMP2017_L12_L13 - IMP2017_L15_L16 - IMP2017_O14 8 livrables PDF
Potential sex difference in the effects of mild acute stress on executive functions
Creators: name: Zhang, Haolu
Publisher: name: University of British Columbia
Year: 2016

description: Prefrontal cortex (PFC)-dependent executive functions (EFs) are critical for reasoning, problem-solving, self-control and planning. The PFC dopamine (DA) level has been demonstrated to modulate EFs in an inverted U-shaped curve, where an intermediate level of DA is optimal. Unlike in other brain regions, PFC DA systems: 1) relies highly on the catechol-O-methyltransferase (COMT) enzyme for clearing released DA; and 2) can be activated even by mild stress. Estradiol (E2) has been shown to down-regulate COMT gene transcription, causing the activity of COMT enzyme to be ~30% less in women than in men. Animal studies have repeatedly shown that stress facilitates cognitive functions dependent on the hippocampus and / or PFC in males, but impairs them in females. Therefore, based on Diamond’s hypothesis that baseline PFC DA levels are higher and closer to the optimal level in women during menstrual phases when their circulating E2 are elevated, than in men, we predicted that mild stress would facilitate EF performance in men but impair it in women when their circulating E2 levels are high. In a crossover design, healthy young adults (both men and women), all COMT Val¹⁵⁸Met heterozygotes, were each tested twice (once with social-evaluative stress and once without, order counterbalanced) on five EF tasks which tapped on the core EFs of inhibitory control, working memory and cognitive flexibility, and one higher-level EF, reasoning. Women were randomly assigned to the low-E2 (F-L) group or high-E2 (F-H) group. Women in the F-L group were tested during the early follicular phase (low E2 level). Women in the F-H group were tested during the midluteal phase (high E2 level). Our social-evaluative procedure was showed to succeed in inducing physiological and subjective stress responses and significantly impaired the performance of the F-H group on one index of inhibitory control, whereas the performance of the M and F-L groups showed a trend towards enhancement. Similar trends (M and F-L: stress-induced enhancement; F-H: stress-induced impairments) were found for some other indices in the first two tasks. These results emphasized that the ways of improving EFs need to be considered in a sex-specific and hormone-dependent manner.
title: IMPERATRICE 2015
Creators: name: Sorin, Sabine
name: CEPAM UMR 7264
Publisher: name: Archeovision
Year: 2021

description: Relevé par photogrammétrie des niveaux d'occupations - Note : 5 fichiers ply : - 00_IMP2015_total_fin_de_fouille - IMP2015_Coupe_L14_L15_L16 - IMP2015_Coupe_S15_S15_S16 - IMP2015_Fond_Abri_CA102 - IMP2015_T16 5 livrables PDF
A Substantial Population of Low Mass Stars in Luminous Elliptical Galaxies
Creators: name: van Dokkum, Pieter
name: Conroy, Charlie
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The stellar initial mass function (IMF) describes the mass distribution of stars at the time of their formation and is of fundamental importance for many areas of astrophysics. The IMF is reasonably well constrained in the disk of the Milky Way but we have very little direct information on the form of the IMF in other galaxies and at earlier cosmic epochs. Here we investigate the stellar mass function in elliptical galaxies by measuring the strength of the Na I doublet and the Wing-Ford molecular FeH band in their spectra. These lines are strong in stars with masses <0.3 Msun and weak or absent in all other types of stars. We unambiguously detect both signatures, consistent with previous studies that were based on data of lower signal-to-noise ratio. The direct detection of the light of low mass stars implies that they are very abundant in elliptical galaxies, making up >80% of the total number of stars and contributing >60% of the total stellar mass. We infer that the IMF in massive star-forming galaxies in the early Universe produced many more low mass stars than the IMF in the Milky Way disk, and was probably slightly steeper than the Salpeter form in the mass range 0.1 - 1 Msun.
description: To appear in Nature
Additional file 1 of Detection and identification of cis-regulatory elements using change-point and classification algorithms
Creators: name: Maderazo, Dominic
name: Flegg, Jennifer A.
name: Algama, Manjula
name: Ramialison, Mirana
name: Keith, Jonathan
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1 ROC curves for GC content