cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Ancestry-related distribution of Runs of homozygosity and functional variants in Qatari population
Creators: name: Mezzavilla, Massimo
name: Cocca, Massimiliano
name: Maisano Delser, Pierpaolo
name: Badii, Ramin
name: Abbaszadeh, Fatemeh
name: Hadi, Khalid Abdul
name: Giorgia, Girotto
name: Gasparini, Paolo
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. Distribution of Y and mitochondrial haplogroups in Qatari samples. Figure S2. Admixture runs from K=3 to K=11.At K=3 we can observe the separation between the Cluster 2 (with African ancestry) and the other three clusters, and we can observe the higher East Asian ancestry in Cluster 4. From K=5 to K=7 we can observe how the Bedouin ancestry is predominant in the Cluster 1 respect to the other clusters. At K=9 we can see how the South Asian (Sindhi)ancestry is becoming predominant in the Cluster 3. Figure S3. Principal component analysis.PC3 versus PC4 on the left panel, PC5 versus PC6 on the right panel. Variance explained by each axis is reported as well. Figure S4. Ancestry proportions in the Qatari sample. The red colour represents the Middle Eastern-Bedouin like ancestry, the cyan colour represents the South Asian component the violet component represents the Middle Eastern-Palestinian like component, the green one represents the African component and the blue one represents the East Asian component. Figure S5. Beanplot of Total Homozygosity in Qatar and 1000G populations. The dotted line represents the average worldwide level of total homozygosity. Figure S6. Genomic distribution of unstandardized —nSL— score. Each line represents the distribution of —nSL— values in each cluster, the dotted line represents the cut-off to discriminate between putatively under selection and neutral markers. Figure S7. Venn Diagram of shared and private signal of selection. The numbers represent the number of SNPs with nSL score over the 99th percentile of the genomic distribution and previously associated to a phenotype (GWAS catalogue) are reported. We can observe how the majority of the variants under selection and previously associated with a phenotype are private of each cluster and only a small fraction is shared between all of them. Figure S8. Regression tree analyses of rs2884737. The analysis shows the different and significant genotype distribution of rs2884737 among the four different cluster found in our dataset. The C allele in homozygous state is more prevalent in Cluster 1. Figure S9. Regression tree analyses of rs1127745. The analysis shows the different and significant genotype distribution of rs1127745 among the four different cluster found in our dataset. The G allele in homozygous state is more prevalent in the Cluster 2. Figure S10. Regression tree analyses of rs35400274. The analysis shows the different and significant genotype distribution of rs35400274 among the four different cluster found in our dataset. The A allele in homozygous state is more prevalent in the Cluster 1 and Cluster 2.
title: Tree algorithms for mining association rules
Creators: name: Goulbourne, Graham.
Publisher: name: University of Liverpool Repository
Year: 2023

description: With the increasing reliability of digital communication, the falling cost of hardware and increased computational power, the gathering and storage of data has become easier than at any other time in history. Commercial and public agencies are able to hold extensive records about all aspects of their operations. Witness the proliferation of point of sale (POS) transaction recording within retailing, digital storage of census data and computerized hospital records. Whilst the gathering of such data has uses in terms of answering specific queries and allowing visulisation of certain trends the volumes of data can hide significant patterns that would be impossible to locate manually. These patterns, once found, could provide an insight into customer behviour, demographic shifts and patient diagnosis hitherto unseen and unexpected. Remaining competitive in a modem business environment, or delivering services in a timely and cost effective manner for public services is a crucial part of modem economics. Analysis of the data held by an organisaton, by a system that "learns" can allow predictions to be made based on historical evidence. Users may guide the process but essentially the software is exploring the data unaided. The research described within this thesis develops current ideas regarding the exploration of large data volumes. Particular areas of research are the reduction of the search space within the dataset and the generation of rules which are deduced from the patterns within the data. These issues are discussed within an experimental framework which extracts information from binary data.
Sodium and potassium intake patterns and trends in South Korea
Creators: name: Popkin, B M
name: Duffey, K J
name: Lee, H-S
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: We examined major trends and patterns regarding sodium and potassium intake and the ratio of sodium and potassium in the diets of South Koreans. We analyzed detailed 24-hour dietary recall data collected from 10,267; 8,819; and 9,264 subjects ages two years and older in the 1998, 2005, and 2009 Korean National Health and Nutrition Examination Surveys, respectively. Mean sodium intake did not change significantly between 1998 and 2009 (4.6 g/d vs 4.7 g/d), while potassium intake increased significantly [2.6 g/d vs. 2.9 g/d (p < 0.001)]. The major dietary sodium sources were kimchi, salt, soy sauce, and soybean paste, and most potassium came from unprocessed foods (white rice, vegetables, kimchi, and fruits). About 50 percent of the participants consumed 4 or more grams of sodium per capita per day. The proportion of respondents consuming 4 to 6 grams of potassium per capita per day increased from 10.3 percent in 1998 to 14.3 percent in 2009 (p < 0.001), and the sodium-potassium ratio decreased from 1.88 to 1.71 (p < 0.001). One major implication is that efforts to reduce sodium in processed foods will be ineffective and future efforts must focus on both education to reduce use of sodium in food preparation and sodium replacement in salt, possibly with potassium.
An optimal quantitative two-scale expansion in stochastic homogenization of discrete elliptic equations
Creators: name: Gloria, Antoine
name: Neukamm, Stefan
name: Otto, Felix
Publisher: name: arXiv
Year: 2014
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: We establish an optimal, linear rate of convergence for the stochastic homogenization of discrete linear elliptic equations. We consider the model problem of independent and identically distributed coefficients on a discretized unit torus. We show that the difference between the solution to the random problem on the discretized torus and the first two terms of the two-scale asymptotic expansion has the same scaling as in the periodic case. In particular the $L^2$-norm in probability of the \mbox{$H^1$-norm} in space of this error scales like $ε$, where $ε$ is the discretization parameter of the unit torus. The proof makes extensive use of previous results by the authors, and of recent annealed estimates on the Green's function by Marahrens and the third author.
Unmasking masked hypertension: prevalence, clinical implications, diagnosis, correlates and future directions
Creators: name: Diaz, K M
name: Schwartz, J E
name: Viera, A J
name: Peacock, J
name: Shimbo, D
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: ‘Masked hypertension’ is defined as having non-elevated clinic blood pressure (BP) with elevated out-of-clinic average BP, typically determined by ambulatory BP monitoring. Approximately 15–30% of adults with non-elevated clinic BP have masked hypertension. Masked hypertension is associated with increased risks of cardiovascular morbidity and mortality compared to sustained normotension (non-elevated clinic and ambulatory BP), which is similar to or approaching the risk associated with sustained hypertension (elevated clinic and ambulatory BP). The confluence of increased cardiovascular risk and a failure to be diagnosed by the conventional approach of clinic BP measurement makes masked hypertension a significant public health concern. However, many important questions remain. First, the definition of masked hypertension varies across studies. Further, the best approach in the clinical setting to exclude masked hypertension also remains unknown. It is unclear whether home BP monitoring is an adequate substitute for ambulatory BP monitoring in identifying masked hypertension. Few studies have examined the mechanistic pathways that may explain masked hypertension. Finally, scarce data are available on the best approach to treating individuals with masked hypertension. Herein, we review the current literature on masked hypertension including definition, prevalence, clinical implications, special patient populations, correlates, issues related to diagnosis, treatment, and areas for future research.
title: Brain Gliosarcoma: A rare primary CNS tumor: About 02 cases and review of the literature
Creators: name: lahlou, anas
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: CNS
subject: Oncology
subject: CT
subject: MR
subject: Biopsy
subject: Surgery
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Gliosarcoma is a rare malignant brain tumor, accounting for 1.8 to 8% of all glial tumors. This entity raises several questions concerning histopathological diagnostic criteria, pathogenesis and therapeutic management. Through tow clinical cases and...
Design Principles For The Organization Of Sales Of Smart Product Service Systems
Creators: name: Schuh, Günther
name: Boos, Wolfgang
name: Holst, Lennard
name: Moser, Benedikt
Publisher: name: Hannover : publish-Ing.
Year: 2023
Subjects: subject: Konferenzschrift
subject: Smart Product Service Systems
subject: Sales Management
subject: Servitization
subject: Sales Organization
subject: Morphological Framework
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: Industrial companies are moving to a solution driven business by offering smart product service systems (Smart PSS). In addition to an existing portfolio of physical goods and technical services, companies develop new digital services and combine all three offerings to an integrated digital solution business. While the development of new digital services does not pose any major challenges for companies, the successful sale of Smart PSS does. Due to changing customer requirements and value propositions of a solution, the sale of Smart PSS requires new design principles for the sales organization compared to the simple sale of physical goods or technical services. While there are already many publications on the topic of industrial sales in research, the description of Smart PSS in particular represents a new field of research. The combination of both topics is therefore not only interesting from a theoretical point of view, but also has a particularly high practical relevance and impact for industrial companies. This paper therefore describes on the one hand, which characteristics can be used to derive customer requirements for Smart PSS and on the other hand, which effects these requirements have on the sales organization of the industrial company. The design principles give recommendations for the organizational structure, the resources, the information systems and the culture of the company depending on the targeted customer type. In order to identify and describe both the customer requirements and the design principles, two morphological boxes were developed based on a literature research and semi-structured interviews with industrial companies. The paper gives an outlook on the different characteristics of the design recommendations and describes first best practices for the successful transformation of the sales organization.
Combining HR-TEM and XPS to elucidate the core–shell structure of ultrabright CdSe/CdS semiconductor quantum dots
Creators: name: Weigert, Florian
name: Müller, Anja
name: Häusler, Ines
name: Geißler, Daniel
name: Skroblin, Dieter
name: Krumrey, Michael
name: Unger, Wolfgang
name: Radnik, Jörg
name: Resch-Genger, Ute
Publisher: name: Technische Universität Berlin
Year: 2020
Subjects: subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik
subject: chemistry
subject: materials science
subject: quantum dots
subject: XPS

description: Controlling thickness and tightness of surface passivation shells is crucial for many applications of core–shell nanoparticles (NP). Usually, to determine shell thickness, core and core/shell particle are measured individually requiring the availability of both nanoobjects. This is often not fulfilled for functional nanomaterials such as many photoluminescent semiconductor quantum dots (QD) used for bioimaging, solid state lighting, and display technologies as the core does not show the application-relevant functionality like a high photoluminescence (PL) quantum yield, calling for a whole nanoobject approach. By combining high-resolution transmission electron microscopy (HR-TEM) and X-ray photoelectron spectroscopy (XPS), a novel whole nanoobject approach is developed representatively for an ultrabright oleic acid-stabilized, thick shell CdSe/CdS QD with a PL quantum yield close to unity. The size of this spectroscopically assessed QD, is in the range of the information depth of usual laboratory XPS. Information on particle size and monodispersity were validated with dynamic light scattering (DLS) and small angle X-ray scattering (SAXS) and compared to data derived from optical measurements. In addition to demonstrating the potential of this novel whole nanoobject approach for determining architectures of small nanoparticles, the presented results also highlight challenges faced by different sizing and structural analysis methods and method-inherent uncertainties.
title: CT angiography in the evaluation of coronary lesions in children with Kawasaki disease
Creators: name: Gagarina, Nina
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Cardiac
subject: Paediatric
subject: Vascular
subject: CT-Angiography
subject: Computer Applications-Detection, diagnosis
subject: Aneurysms

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Kawasaki disease is an acute systemic vasculitis with coronary artery lesions, mostly with aneurysms formations. Coronary CT angiography has the high accuracy in detection and characterization of coronary artery aneurysms. The main reasons for...
Factor relationships of metabolic syndrome and echocardiographic phenotypes in the HyperGEN study
Creators: name: Kraja, Aldi T
name: de Simone, Giovanni
name: Rao, Dabeeru C
name: Rice, Treva
name: Hunt, Steven C
name: Huang, Pinchia
name: North, Kari E
name: Arnett, Donna K
name: Devereux, Richard B
name: Lewis, Cora E
name: Tang, Weihong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Metabolic Syndrome (MetS) and its risk factors are predictors of cardiovascular events. MetS is also directly associated with echocardiographic (ECHO) phenotypes. The current study is the first to investigate factors associated with both MetS risk factors and echocardiographic phenotypes and to assess their heritability. Multivariate factor analysis (FA) was performed on 15 traits in 1,393 African Americans and 1,133 Caucasians, as well as stratified by type 2 diabetes mellitus (DM) status. FA with Varimax rotation established four to five latent factors across ethnicities and DM stratifications. Among MetS risk factors, BP was most highly correlated with cardiac traits. The factor domains, ordered by the proportion of variance explained, were “LV wall thickness,” “LV geometry,” “BP,” “body mass index-insulin,” and “lipid-insulin.” FA without any rotation identified special (cross domain) MetS-ECHO factors, “BP-LV geometry” and “BP-LV dimension-wall thickness” in Caucasians. Of the total original risk factors variance, 50%–57% of it was explained by the latent factors. Heritabilities were highest for body mass index-insulin (37–53%), lowest for “BP” factors (15–27%) and intermediate for MetS-ECHO factors. These identified latent factors can be utilized as summary phenotypes in epidemiological, linkage and association studies.
Autoregulation after ischaemic stroke
Creators: name: Aiyagari, Venkatesh
name: Videen, Tom O
name: Diringer, Michael N
name: Powers, William J
name: Zazulia, Allyson R
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Absent outcome data from randomized clinical trials, management of hypertension in acute ischaemic stroke remains controversial. Data from human participants have failed to resolve the question whether cerebral blood flow (CBF) in the peri-infarct region will decrease due to impaired autoregulation when systemic mean arterial pressure (MAP) is rapidly reduced.
title: Exclusive use of T2-weighted HASTE sequences in routine Magnetic Resonance Cholangiopancreatography examination for intraductal biliary stones
Creators: name: Chia, Elisa
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Calcifications / Calculi
subject: Imaging sequences
subject: Computer Applications-Detection, diagnosis
subject: Biliary Tract / Gallbladder
subject: Abdomen
subject: MR-Cholangiography

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Magnetic Resonance Cholangio-pancreatography (MRCP) has been increasingly used for the evaluation of the pancreato-biliary tree over the past few decades. As a non-invasive alternative for the investigation of intraductal biliary calculus for high...
Screening of an electrically charged particle in a two-dimensional two-component plasma at $Γ=2$
Creators: name: Ferrero, Alejandro
name: Téllez, Gabriel
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider the thermodynamic effects of an electrically charged impurity immersed in a two-dimensional two-component plasma, composed by particles with charges $\pm e$, at temperature $T$, at coupling $Γ=e^2/(k_B T)=2$, confined in a large disk of radius $R$. Particularly, we focus on the analysis of the charge density, the correlation functions, and the grand potential. Our analytical results show how the charges are redistributed in the circular geometry considered here. When we consider a positively charged impurity, the negative ions accumulate close to the impurity leaving an excess of positive charge that accumulates at the boundary of the disk. Due to the symmetry under charge exchange, the opposite effect takes place when we place a negative impurity. Both the cases in which the impurity charge is an integer multiple of the particle charges in the plasma, $\pm e$, and a fraction of them are considered; both situations require a slightly different mathematical treatments, showing the effect of the quantization of plasma charges. The bulk and tension effects in the plasma described by the grand potential are not modified by the introduction of the charged particle. Besides the effects due to the collapse coming from the attraction between oppositely charged ions, an additional topological term appears in the grand potential, proportional to $-n^2\ln(mR)$, with $n$ the dimensionless charge of the particle. This term modifies the central charge of the system, from $c=1$ to $c=1-6n^2$, when considered in the context of conformal field theories.
description: 26 pages, 11 figures
title: The biology and control of Azolla filiculoides Lam. and Lemna minuta Kunth.
Creators: name: Ann. Janes, Rachel
Publisher: name: University of Liverpool Repository
Year: 2023

description: The aim of this study was to improve our understanding of the biology of two alien, invasive, free-floating species, the Water Fern Azollafiliculoides and the Least Duckweed Lemna minUla, which cause severe weed problems in Britain. Hence, control practices, which had been based upon anecdotal information, could be given a scientific foundation. An appraisal of the known distributions of the two species in Britain was undertaken. From an analysis of spread to date, it can be predicted that L. minUla will be present in 150 and A.filiculoides in 500, 10 x 10 km grid squares by the year 2000. Neither A. filiculoides nor L. minuta produce specialised overwintering structures and both rely heavily on ordinary, vegetative plants to overwinter. It was found that vegetative plants of both species can survive encasement in ice and laboratory studies show that they can withstand short exposure to sub-zero temperatures above approximately -4 °C. However, field evidence suggests that both species can survive much more severe temperature conditions, so both are considerably less cold-sensitive than previously suggested. L. minuta is not known to reproduce sexually in Britain. However, A. filiculoides sporulates regularly over a wide geographical range to produce numerous, viable sporocarps. These sporocarps form a 'seed' bank in the sediment and may ensure population survival because they are more freeze- and desiccation- tolerant than adult plants. Sporocarps require temperatures of not less than 10 °C and a short burst of light to germinate. L. min uta plants vary very little seasonally (although larger summer fronds can be easily confused with the common, native duckweed Lemna minor). In contrast, three forms of A. jilicuJoides can be identified; survival, mat and colonising. Competition experiments suggested the following tentative order of decreasing competitive ability; A. filiculoides > L. minuta > L. minor. This was probably a result of the more erect A filiculoides plants growing over the Lemna fronds. Not all field evidence supports this finding. Floating mats of A.filiculoides and L. minuta cause similar ecological problems because they reduce light, pH and oxygen and increase detrit~:s and probably alter nutrient loading. Laboratory studies showed that morphologically and physiologically plastic species of submerged plants, ego Elodea nuttall;;, could withstand these conditions better than less adaptable species, ego Potamogeton crispus. Four chemical control methods were tested over a range of dosages in the laboratory; diquat (as both spray and sub-surface injection), glyphosate (as spray) and terbutryn (as sub-surface application). These treatments were unsuccessful in controlling L. minuta, in contrast to anecdotal field evidence where terbutryn is considered effective. Glyphosate and diquat sprayed at 1.8 kg ai ha-1 and 1 kg ai ha-1 controlled A. jiliculoides. A. jiliculoides sporocarps were resistant to all chemical treatments.
Angiotensin II Type 1A Receptors in Vascular Smooth Muscle Cells Do Not Influence Aortic Remodeling in Hypertension
Creators: name: Sparks, M. A.
name: Haystead, T. A. J.
name: Snouwaert, J.
name: Vivekanandan-Giri, A.
name: Fortner, C. N.
name: Parsons, K. K.
name: Koller, B.
name: Stegbauer, J.
name: Gurley, S. B.
name: Griffiths, R. C.
name: Le, T. H.
name: Coffman, T. M.
name: Raasch, E. W.
name: Pennathur, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Vascular injury and remodeling are common pathological sequelae of hypertension. Previous studies have suggested that the renin-angiotensin system (RAS) acting through the type I (AT1) angiotensin (AT1)-receptor promotes vascular pathology in hypertension. To study the role of AT1-receptors in this process, we generated mice with cell-specific deletion of AT1-receptors in VSMCs using Cre/Loxp technology. We crossed the SM22α-Cre transgenic mouse line expressing Cre recombinase in smooth muscle cells with a mouse line bearing a conditional allele of the Agtr1a gene (Agtr1a flox), encoding the major murine AT1-receptor isoform (AT1A). In SM22α-Cre+Agtr1a flox/flox (SMKO) mice, AT1A-receptors were efficiently deleted from VSMCs in larger vessels, but not from resistance vessels such as pre-glomerular arterioles. Thus, vasoconstrictor responses to angiotensin II were preserved in SMKOs. To induce hypertensive vascular remodeling, mice were continuously infused with angiotensin II for 4 weeks. During infusion of angiotensin II, blood pressures increased significantly and to a similar extent in SMKOs and controls. In control mice, there was evidence of vascular oxidative stress indicated by enhanced nitrated tyrosine residues in segments of aorta; this was significantly attenuated in SMKOs. Despite these differences in oxidative stress, the extent of aortic medial expansion induced by angiotensin II infusion was virtually identical in both groups. Thus, vascular AT1A-receptors promote oxidative stress in the aortic wall but are not required for remodeling in angiotensin II-dependent hypertension.
title: Optimization of Contrast agent dosage on Contrast-enhanced T2 FLAIR: An In-Vitro and Animal-Model Study
Creators: name: Rui, Wenting
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Cancer
subject: Contrast agent-intravenous
subject: MR
subject: Contrast agents

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Gadolinium-based contrast agent (GBCA) is routinely used as an intravenous magnetic resonance imaging (MRI) contrast agent for better brain lesion detection.Nephrogenic systemic fibrosis, a morbid and deadly disease, has been found to be closely...
Taeniorhynchus (Coquillettidia) flavus Yentrillon.
Creators: name: F. W. Edwards
Publisher: name: Zenodo
Year: 1920
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Culicidae
Taeniorhynchus
Taeniorhynchus flavus

description: Taeniorhynchus (Coquillettidia) flavus, Yentrillon. Culex Jlavus, Ventrillon ( nee Motschulsky), Bull. Mus. Paris, x, p. 55 0 (1904). Culex grandidieri, Blanchard, Les Moustiques, p. 62 7 (1905). Several females, including cotypes of Ventrillon, from Tananarive (Dr. Ventrillon, 1905). This is very close to the African T. fuscopennatus, of which it may be a mere local form; the hypopygia are very similar, as is shown by a drawing taken from Ventrillon's male cotype which M. Seguy kindly sent me; this indicates the clasper as having a rather different shape. T. jlavus, however, in all the examples I have seen, is readily distinguishable by the coloration of the scales on the wing, particularly the apical half. The costa is yellow, with a line of black scales on the outer margin on its basal two-thirds; subcostal and first longitudinal veins predominantly yellow, • apically entirely so; stems of fork-cells and tips of veins round wing-tip yellow; remaining veins and fringe mainly black. This description is considerably at variance with that of Ventrillon, but an examination of the cotypes showed that Ms was inaccurate. T. fuscopennatus differs in having the dark and light wing-scales fairly evenly mixed, and also in having the integument of the thorax blackish or dark brown, that of T. flavus being light brown. T. aureus, Edw., has an almost greater resemblance even than T. fuscopennatus, but it again has a rather differently shaped clasper, and has the costa entirely yellow. I have adopted the name flavus rather than grandidieri, because the Culex jlavus of Motschulsky is probably an Aeies, Ventrillon's later flavus being therefore valid in the genus Taeniorhynchus.
description: Published as part of F. W. Edwards, 1920, Bulletin of Entomological Research, pp. 133-138 in Bulletin of Entomological Research 11 (2) on page 5, DOI: 10.1017/S0007485300044539, http://zenodo.org/record/163545
Documenting Data Production Processes: A Participatory Approach for Data Work
Creators: name: Miceli, Milagros
name: Yang, Tianling
name: Alvarado Garcia, Adriana
name: Posada, Julian
name: Wang, Sonja Mei
name: Pohl, Marc
name: Hanna, Alex
Publisher: name: Technische Universität Berlin
Year: 2022
Subjects: subject: 000 Informatik, Informationswissenschaft, allgemeine Werke::000 Informatik, Wissen, Systeme::004 Datenverarbeitung; Informatik
subject: 600 Technik, Medizin, angewandte Wissenschaften::600 Technik::600 Technik, Technologie
subject: 300 Sozialwissenschaften::300 Sozialwissenschaften, Soziologie::301 Soziologie, Anthropologie
subject: dataset documentation
subject: data production
subject: data work
subject: data labeling
subject: data annotation
subject: machine learning
subject: transparency

description: The opacity of machine learning data is a significant threat to ethical data work and intelligible systems. Previous research has addressed this issue by proposing standardized checklists to document datasets. This paper expands that field of inquiry by proposing a shift of perspective: from documenting datasets towards documenting data production. We draw on participatory design and collaborate with data workers at two companies located in Bulgaria and Argentina, where the collection and annotation of data for machine learning are outsourced. Our investigation comprises 2.5 years of research, including 33 semi-structured interviews, five co-design workshops, the development of prototypes, and several feedback instances with participants. We identify key challenges and requirements related to the integration of documentation practices in real-world data production scenarios. Our findings comprise important design considerations and highlight the value of designing data documentation based on the needs of data workers. We argue that a view of documentation as a boundary object, i.e., an object that can be used differently across organizations and teams but holds enough immutable content to maintain integrity, can be useful when designing documentation to retrieve heterogeneous, often distributed, contexts of data production.
Midgestation Maternal Serum 25-Hydroxyvitamin D Level and Soluble Fms-Like Tyrosine Kinase 1/Placental Growth Factor Ratio as Predictors of Severe Preeclampsia
Creators: name: Long, D. L.
name: Brittain, J. E.
name: Stuebe, A. M.
name: Haeri, S.
name: Camargo, C. A.
name: Baker, A. M.
name: Woodham, P. C.
name: Boggess, K. A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Recent studies have shown that low serum 25-hydroxyvitamin D (25[OH]D) level is a risk factor for preeclampsia. The clinical significance of in vitro findings that vitamin D regulates vascular endothelial growth factor production is unclear. We sought to determine whether there is an association between midgestation serum 25(OH)D levels and angiogenic factor activity and to compare their predictive value for the development of severe preeclampsia. We conducted a nested case-control study of women with severe preeclampsia (n=41) versus women with uncomplicated term birth (n=123) who had second trimester genetic screening (15–20 weeks). Using banked frozen serum, we measured levels of 25(OH)D, vascular endothelial growth factor, soluble fms-like tyrosine kinase 1, and placental growth factor and compared their correlations and predictive values. We found no correlation between serum 25(OH)D and angiogenic factors levels. 25(OH)D alone was comparable to vascular endothelial growth factor and soluble fms-like tyrosine kinase 1/placental growth factor ratio as a predictive marker for severe preeclampsia. A composite of both 25(OH)D level and soluble fms-like tyrosine kinase 1/placental growth factor ratio was more predictive than either alone (area under curve: 0.83 versus 0.74 and 0.67, respectively). In conclusion, combining midpregnancy 25(OH)D level with soluble fms-like tyrosine kinase 1/placental growth factor ratio provides a better prediction for the development of severe preeclampsia.
Genes and environment: novel, functional polymorphism in the human cathepsin L (CTSL1) promoter disrupts a xenobiotic response element (XRE) to alter transcription and blood pressure
Creators: name: Kim, Hyung-Suk
name: O’Connor, Daniel T.
name: Friese, Ryan S.
name: Waalen, Jill
name: Mbewe-Campbell, Nzali
name: Zhang, Kuixing
name: Mahata, Manjula
name: Rao, Fangwen
name: Chiron, Stephane
name: Nievergelt, Caroline M.
name: Mahata, Sushil K.
name: Schork, Andrew J.
name: Wei, Zhiyun
name: Hook, Vivian Y.
name: Biswas, Nilima
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Cathepsin L (CTSL1) catalyzes the formation of peptides that influence blood pressure (BP). Naturally occurring genetic variation or targeted ablation of the Ctsl1 locus in mice yield cardiovascular pathology. Here, we searched for genetic variation across the human CTSL1 locus and probed its functional effects, especially in the proximal promoter.
Additional file 1 of Characteristics of pleural effusion with a high adenosine deaminase level: a case–control study
Creators: name: Shimoda, Masafumi
name: Hirata, Aya
name: Tanaka, Yoshiaki
name: Morimoto, Kozo
name: Yoshiyama, Takashi
name: Yoshimori, Kozo
name: Saraya, Takeshi
name: Ishii, Haruyuki
name: Ohta, Ken
Publisher: name: figshare
Year: 2022
Subjects: subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 1. Program code for development of a decision tree.
Genetic Variants in Arhgef11 Are Associated With Kidney Injury in the Dahl Salt-Sensitive Rat
Creators: name: Johnson, A. C.
name: Roman, R. J.
name: Stelloh, C.
name: Dreisbach, A. W.
name: Garrett, M. R.
name: Williams, J. M.
name: Regner, K. R.
name: Townsend, R. R.
name: Franceschini, N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: A previous genetic analysis comparing the Dahl salt-sensitive (S) rat to the spontaneously hypertensive rat (SHR) identified a major locus on chromosome 2 that influences proteinuria in the S rat. In the present study, blood pressure, proteinuria, and renal hemodynamics were evaluated in congenic strains with small segments of the protective SHR genome on the S background. Proteinuria and renal function were significantly improved in the congenic strains compared to the S. The causative locus interval was narrowed to Arhgef11, Pear1, and Sh2d2 were identified as important candidate genes that may be linked to kidney injury in the S rat. In particular, Arhgef11 plays an important role in the activation of the Rho-ROCK signaling pathway. Inhibition of this pathway using fasudil resulted in a significant reduction of proteinuria in treated S rats (compared to untreated S). However, no difference was observed between treated or untreated SHR or congenic strains. The homologous region in humans was found to be associated with estimated glomerular filtration rate (eGFR) in the Candidate Gene Association Resource (CARe) population. In summary, these findings demonstrate that allelic variants in Arhgef11, acting through the Rho-ROCK pathway, could influence kidney injury in the S as well as provide insight into human kidney disease.
Electrical permittivity driven metal-insulator transition in heterostructures of nonpolar Mott- and band insulators
Creators: name: Omori, Yukiko
name: Rüegg, Andreas
name: Sigrist, Manfred
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Metallic interfaces between insulating perovskites are often observed in heterostructures combining polar and nonpolar materials. In these systems, the polar discontinuity across the interface may drive an electronic reconstruction inducing free carriers at the interface. Here, we theoretically show that a metallic interface between a Mott- and a band-insulator can also form in the absence of a polar discontinuity. The condition for the appearance of such a metallic state is consistent with the classical Mott criterion: the metallic state is stable if the screening length falls below the effective Bohr radius of a particle-hole pair. In this case, the metallic state bears a remarkable similarity to the one found in polar/nonpolar heterostructures. On the other hand, if the screening length approaches the size of the effective Bohr radius, particles and holes are bound to each other resulting in an overall insulating phase. We analyze this metal-insulator transition, which is tunable by the dielectric constant, in the framework of the slave-boson mean-field theory for a lattice model with both onsite and long-range Coulomb interactions. We discuss ground-state properties and transport coefficients, which we derive in the relaxation-time approximation. Interestingly, we find that the metal-insulator transition is accompanied by a strong enhancement of the Seebeck coefficient in the band-insulator region in the vicinity of the interface. The implications of our theoretical findings for various experimental systems such as nonpolar (110) interfaces are also discussed.
description: 13 pages, 14 figures
Nighttime Blood Pressure Dipping in Young Adults and Coronary Artery Calcium 10-15 Years Later: The Coronary Artery Risk Development in Young Adults Study
Creators: name: Hinderliter, A. L.
name: Shimbo, D.
name: Pletcher, M. J.
name: Person, S. D.
name: Jacobs, D. R.
name: Viera, A. J.
name: Lin, F.-C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Nighttime blood pressure (BP) dipping can be quantified as the ratio of mean nighttime (sleep) BP to mean daytime (awake) BP. People whose dipping ratio is 0.90 have been referred to as nondippers, and nondipping is associated with cardiovascular disease events. We examined the relationship between systolic nighttime BP dipping in young adults and presence of coronary artery calcium (CAC) 10-15 years later using data from the ambulatory BP monitoring substudy of the Coronary Artery Risk Development in Young Adults (CARDIA) study. Among 239 participants with adequate measures of both nighttime and daytime readings and coronary artery calcium, the systolic BP dipping ratio ranged from 0.72 to 1.24 (mean 0.88, SD 0.06), and CAC was present 10 to 15 years later in 54 participants (22.6%). Compared to those whose systolic BP dipping ratio ranged from 0.88 to 0.92 (Quartile 3), the 57 participants (23.9%) with less pronounced or absent dipping (ratio 0.92 to 1.24, Quartile 4) had an unadjusted odds ratio of 4.08 (95% CI 1.48-11.2) for presence of CAC. The 60 participants (25.1%) with a more pronounced dipping (ratio 0.72 to 0.85, Quartile 1) also had greater odds for presence of CAC (OR 4.76; 95% CI 1.76-12.9). When modeled as a continuous predictor, a U-shaped relationship between systolic BP dipping ratio and future CAC was apparent, and persisted after adjustment for multiple potential confounders (p
title: Radiological pulmonary manifestations of scleroderma and synchronic pneumoconiosis.
Creators: name: Narbona Diez, Ana
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: CT-High Resolution
subject: CT
subject: Thorax
subject: Respiratory system
subject: Lung
subject: Diagnostic procedure
subject: Connective tissue disorders
subject: Inflammation
subject: Occupational / Environmental hazards

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: -To recognize typical and atypical pulmonary image findings of scleroderma and pneumoconiosis. - To be aware of the possibility of having scleroderma and synchronic pneumoconiosis in the same patient and avoid “satisfaction of search”...
The influence of a power law distribution of cluster size on the light transmission of disordered 1D photonic structures
Creators: name: Bellingeri, Michele
name: Scotognella, Francesco
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: A better understanding of the optical properties of random photonic structures is beneficial for many applications, such as random lasing, optical imaging and photovoltaics. Here we investigated the light transmission properties of disordered photonic structures in which the high refractive index layers are aggregated in clusters. We sorted the size of the clusters from a power law distribution tuning the exponent a of the distribution function. The sorted high refractive layer clusters are randomly distributed within the low refractive index layers. We studied the total light transmission, within the photonic band gap of the corresponding periodic crystal, as a function of the exponent in the distribution. We observed that, for a within the interval [0,3.5], the trend can be fitted with a sigmoidal function.
description: 9 pages, 7 Figures, 1 Table
Additional file 2 of Characteristics of pleural effusion with a high adenosine deaminase level: a case–control study
Creators: name: Shimoda, Masafumi
name: Hirata, Aya
name: Tanaka, Yoshiaki
name: Morimoto, Kozo
name: Yoshiyama, Takashi
name: Yoshimori, Kozo
name: Saraya, Takeshi
name: Ishii, Haruyuki
name: Ohta, Ken
Publisher: name: figshare
Year: 2022
Subjects: subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 2: Table S1. The area under the receiver operating characteristic curve of predictive factors for the diagnosis of a target disease compared to all other diseases.
Heredity and cardiometabolic risk: naturally occurring polymorphisms in the human neuropeptide Y2 receptor promoter disrupt multiple transcriptional response motifs
Creators: name: Kim, Hyung-Suk
name: Mahata, Sushil K.
name: Rao, Fangwen
name: Wen, Gen
name: O’Connor, Daniel T.
name: Wei, Zhiyun
name: Miramontes-Gonzalez, Jose P.
name: Shih, Pei-an B.
name: Balasubramanian, Karthika
name: Schmid-Schoenbein, Geert W.
name: Zhang, Kuixing
name: Friese, Ryan S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The neuropeptide Y2 G-protein-coupled receptor (NPY2R) relays signals from PYY or neuropeptide Y toward satiety and control of body mass. Targeted ablation of the NPY2R locus in mice yields obesity, and studies of NPY2R promoter genetic variation in more than 10 000 human participants indicate its involvement in control of obesity and BMI. Here we searched for genetic variation across the human NPY2R locus and probed its functional effects, especially in the proximal promoter.
title: Complications and seeding in CT-guided high-dose-rate brachytherapy (CT-HDRBT) - a preliminary quantitative analysis
Creators: name: Böning, Georg
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Interventional non-vascular
subject: Oncology
subject: CT
subject: Brachytherapy
subject: Radiation therapy / Oncology
subject: Cancer
subject: Image guided radiotherapy
subject: Radiotherapy techniques

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Computed tomography-guided high-dose-rate brachytherapy (CT-HDRBT) is a minimally-invasive therapeutic option for patients with unresectable tumors. After multi-disciplinary tumor-board decision a pre-interventional imaging is performed either as...
Understanding shock-cloud interaction on the supernova remnant RCW86 with Athena
Creators: name: Bamba, Aya
name: Tamazaki, Ryo
name: Sano, Hidetoshi
name: Vink, Jacco
Publisher: name: Zenodo
Year: 2022

description: Oral presentation in "Exploring the Hot and Energetic Universe: the third scientific conference dedicated to the Athena X-ray Observatory".
title: Focal breast lesions in clinical CT examinations of the chest: a retrospective analysis of prospectively acquired CT data
Creators: name: Krug, Kathrin
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Thorax
subject: CT
subject: Diagnostic procedure
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: In retrospective studies based on the written radiological reports the percentage of breast cancers visualized as incidental findings in routine CT examinations of the chest is estimated at ≤2% [1-7]. In view of the constantly rising number of CT...
Additional file 10 of Association between migraine and cognitive impairment
Creators: name: Gu, Lihua
name: Wang, Yanjuan
name: Shu, Hao
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 10: Figure S6. Subgroup analysis regarding comparison in visuospatial function between migraine group and no migraine group in different ethnicities. Abbreviations: CI, confidence interval; SMD, standard mean difference.
Associations between age, cohort, and urbanization with SBP and DBP in China: a population-based study across 18 years
Creators: name: Herring, Amy H.
name: Gordon-Larsen, Penny
name: Popkin, Barry M.
name: Zhang, Bing
name: Du, Shufa
name: Attard, Samantha M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Little is known about whether large-scale environmental changes, such as those seen with urbanization, are differentially associated with systolic versus diastolic blood pressure, and whether those changes vary by birth cohort.
Immigration and Sexual Partner Risk Among Latino Adolescents in San Francisco
Creators: name: Doherty, I.
name: Minnis, A. M.
name: Cheng, H.
name: Otero-Sabogal, R.
name: Padian, N. S.
name: vanDommelen-Gonzalez, E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Sexual partner characteristics increase risk for adverse reproductive health outcomes. Evidence is limited regarding whether choice of sexual partners among Latino adolescents changes with U.S. acculturation/adaptation.
title: Vascular plug embolization of the common iliac artery for aorto-uni-iliac EVAR.
Creators: name: BALLANO FRANCO, CARLOS
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Vascular
subject: Fluoroscopy
subject: Arterial access
subject: Embolisation
subject: Aneurysms

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To evaluate the safety and efficacy of the Amplatzer vascular plug (AVP) for embolization of common iliac arteries during aorto-uni-iliac endovascular aortic aneurysm repair...
Additional file 11 of Association between migraine and cognitive impairment
Creators: name: Gu, Lihua
name: Wang, Yanjuan
name: Shu, Hao
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 11: Figure S7. Subgroup analysis regarding comparison in attention between migraine group and no migraine group in different ethnicities (A) and study types (B). Abbreviations: CI, confidence interval; SMD, standard mean difference.