cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Improving malignant hyperthermia education for the non-operating room environment through high-fidelity simulation: A quality improvement project
Creators: name: Kreglo, Brenna + Nakahara, Ron
Publisher: name: Oregon Health and Science University
Year: 2023
Subjects: subject: NORA + Non-operating room anesthesia + malignant hyperthermia + simulation

description: BACKGROUND: Malignant hyperthermia (MH) is a rare medical crisis that carries a dramatically decreased mortality rate when treated promptly. Training is not routine in the non- operating room anesthesia (NORA) setting. As NORA is becoming more prevalent, NORA clinical staff must have the appropriate training to respond to this emergency.
PURPOSE: The purpose of this quality improvement (QI) project was to improve the education of NORA clinical staff in the identification and management of MH. A secondary aim was to identify local institutional barriers in responding to an MH crisis and thus revise the standard operating procedures (SOP) accordingly.
METHODS: This project occurred at a single-center acute care medical facility. A total of 69 registered nurses, licensed practical nurses, and technicians participated in ten high-fidelity in situ MH simulations. Staff education was evaluated using pre- and post-simulation knowledge quizzes. Staff confidence surrounding MH was evaluated through Likert self-evaluations, debriefings, and thematic analysis. Simulations were observed to guide changes to the SOP. RESULTS: Participants’ mean knowledge quiz scores improved from 60% to 89% post- intervention (p<0.001). Mean Likert scores improved from 2.6 to 4.4 pre- and post-simulation respectively (p<0.001), demonstrating a significant improvement in confidence in the management of MH. Qualitative feedback identifying barriers in the MH response guided appropriate changes to the SOP.
CONCLUSION: High-fidelity, in-situ simulation was an effective method to improve NORA staff education and make meaningful improvements to the facility’s MH SOP. Expansion of MH training into NORA areas presents a potential QI opportunity for other institutions to explore.
title: Plastic waste interferes with chemical communication in aquatic ecosystems
Creators: name: Trotter, Benjamin
name: Ramsperger, Anja
name: Raab, Patricia
name: Haberstroh, Julia
name: Laforsch, Christian
Publisher: name: University of Bayreuth
Year: 2019
Subjects: subject: 500
subject: 570

description: nvironmental pollution with plastic waste has gained increasing attention, as the contamination of aquatic habitats poses a challenge to these ecosystems. Plastic waste has direct negative effects on animals such as reduced growth rate, fecundity or life span. However, the indirect effects of plastic waste, which has the ability to sorb chemicals from the surrounding media, on chemical communication have yet to be investigated. Chemical communication is crucial for aquatic organisms, e.g., to avoid predation. The planktonic water flea Daphnia (Crustacea), an important link between trophic levels, relies on info-chemicals (kairomones) to assess its current predation risk and to form inducible defences. We show that plastic waste, composed of high-density polyethylene (HDpe) and polyethylene terephthalate (pet) interferes with the formation of inducible defences in Daphnia longicephala when exposed to a combination of kairomones of Notonecta glauca and plastic waste. D. longicephala shows a reduction in all defensive traits, including body length, crest width and time until primiparity, compared to exposure to solely kairomone conditioned media. plastic waste in the absence of kairomones had no effect on defensive traits. Since it is vital to adjust these defences to the current predation risk, any misperception can have far-reaching ecological consequences. therefore, plastic waste can have indirect effects on organisms, which may manifest at the community level.
CYP1B1 mutational screening in a Portuguese cohort of primary congenital glaucoma patients
Creators: name: M. J. Simões
name: S. Carmona
name: R. Roberts
name: G. Wainwright
name: C. Faro
name: E. Silva
name: C. Egas
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: Science Policy
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: CYP1B1 mutational screening in a Portuguese cohort of primary congenital glaucoma patients
Σχεδιασμός Διαδικτυακής Κοινότητας Πρακτικής: Η Εκπαιδευτική Κοινότητα «STEAM-Robots»
Creators: name: Milakis, Emmanouil
Publisher: name: figshare
Year: 2022
Subjects: subject: 130306 Educational Technology and Computing
subject: FOS: Educational sciences
subject: Education
subject: 130106 Secondary Education
subject: 130313 Teacher Education and Professional Development of Educators

description: This paper describes the design of an online community of practice for educators and have as a common goal the promotion of STEAM and Robotics Education and the creation of corresponding interdisciplinary educational material. Through the above prism are presented the characteristics and theoretical principles of a community of Practice and their respective models of analysis. At the same time, the possibility of utilizing modern internet tools for the technical support of such an effort is being explored.
title: Mainstreaming disability on Radio 4
Creators: name: Sweeney, Brian J.
Publisher: name: University of Glasgow
Year: 2003

description: In the autumn of 1997 it was announced that Radio 4's programmes were to be rescheduled and a commitment was given that disability would become a mainstream issue for the network. The new schedule and the mainstreaming initiative were implemented in April 1998. One of the immediate effects of rescheduling was the disappearance of Does He Take Sugar?, the network's weekly programme which presented in-depth treatment of general disability issues. By way of replacement, You and Yours, Radio 4's consumerist programme of longstanding, was given the remit to include regular coverage of disability issues in its content. It was intended that the outcome of these decisions would be that regular coverage of disability would emerge from a niche slot within the network and be positioned within the mainstream of the network's output. On the one hand, the implementation of the proposal to mainstream disability yielded the possibility of an increase in the coverage of disability issues on Radio 4 in an integrated way. On the other hand it could mean a loss of effective and focused treatment of disability issues and a qualitative shift in the nature of coverage. The proposal to mainstream disability issues on Radio 4 thus touched on central issues concerning the treatment of socially disadvantaged groups and the quest for equality. Its implementation took place at a time when the UK disability movement was growing in political power, and disabled people in Britain were becoming aware of the promise of potentially beneficial socio-cultural changes reflected by developments such as the introduction of the Disability Discrimination Act CDDA 1995). This thesis examines three aspects of the introduction of the mainstreaming initiative and the early years of its implementation: a) it draws on interviews with key players, conversations with others involved, participant observation reports and documentary evidence to examine the rationale behind the mainstream initiative and, in the light of the decision to drop the network's programme which focussed on general disability issues (Does He Take Sugar?), it examines the decision to retain In Touch, the network's niche programme for blind or visually impaired listeners; b) it presents a quantitative and qualitative comparative analysis of the network's pre and post-mainstreaming treatment of disability issues. This includes analysis of ten editions of Does He Take Sugar? the disability issues covered in You and Yours during the months of September 1998, 1999,2000 and analysis of the series No Triumph, No Tragedy. presented by a former member of the Does He Take Sugar? team in the summer of 2000;
SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation
Creators: name: Zong-Bo Wei
name: Ye-Feng Yuan
name: Jaouen, Florence
name: Ma, Mei-Sheng
name: Chan-Juan Hao
name: Zhang, Zhe
name: Chen, Quan
name: Zengqiang Yuan
name: Yu, Li
name: Beurrier, Corinne
name: Li, Wei
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences

description: Searching for new regulators of autophagy involved in selective dopaminergic (DA) neuron loss is a hallmark in the pathogenesis of Parkinson disease (PD). We here report that an endoplasmic reticulum (ER)-associated transmembrane protein SLC35D3 is selectively expressed in subsets of midbrain DA neurons in about 10% TH (tyrosine hydroxylase)-positive neurons in the substantia nigra pars compacta (SNc) and in about 22% TH-positive neurons in the ventral tegmental area (VTA). Loss of SLC35D3 in ros (roswell mutant) mice showed a reduction of 11.9% DA neurons in the SNc and 15.5% DA neuron loss in the VTA with impaired autophagy. We determined that SLC35D3 enhanced the formation of the BECN1-ATG14-PIK3C3 complex to induce autophagy. These results suggest that SLC35D3 is a new regulator of tissue-specific autophagy and plays an important role in the increased autophagic activity required for the survival of subsets of DA neurons.
Organotin(IV) complexes with 2-hydroxynaphthaldehyde-N(4)-ethylthiosemicarbazone: Synthesis, characterization, and in vitro antibacterial activity
Creators: name: M. A. Salam
name: Md. Azharul Arafath
name: Mouayed A. Hussein
name: Rabeya Basri
name: Pervin, Rehana
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Four new organotin(IV) complexes with 2-hydroxynaphthaldehyde-N(4)-ethylthiosemicarbazone [(H2DNET), (1)] of the type [MeSnCl(DNET] (2), [BuSnCl(DNET)] (3), [PhSnCl(DNET)] (4), and [Ph2Sn(DNET] (5) have been synthesized by the direct reaction of H2DNET (1) with organotin(IV) chloride(s) in the presence of potassium hydroxide in absolute methanol. All the compounds were characterized by elemental analyses, molar conductivity, UV-Vis, IR, 1H, 13C, and 119Sn NMR spectral studies. The molecular structure of ligand (1) has been confirmed by X-ray single crystal diffraction. Spectroscopic data clearly suggested that Sn(IV) center is coordinated with the ONS tridentate ligand (H2DNET) and exhibits a five-coordinate geometry in solution. Antibacterial studies were carried out in vitro against four bacterial strains. All organotin(IV) compounds (2–5) showed good activity against various bacteria but lower activity than the reference drug (Ciprofloxacin). The results demonstrate that organic groups attached to tin(IV) moiety have significant effect on their biological activities. Among them, diphenyltin(IV) derivative 5 exhibits significantly good activity than the other organotin(IV) derivatives (2–4).
How Competency Mapping Facilitates a Sense of Purpose and Fuel Emotional Engagement
Creators: name: Sachin Pandey
name: Tanushree Singh
name: Pravar Dhanraj Singh
name: Dr. Rajlaxmi Srivastava
Publisher: name: Institute for Interdisciplinary and Venture Publication
Year: 2025
Subjects: Competency Mapping
Role clarity
Emotional Engagement
Personal Growth
Talent Management

description: We are going to discuss and explore the essential role of competency mapping in cultivating a profound sense of purpose and driving powerful emotional engagement within organizations. Instead of just giving people jobs to do, competency mapping carefully identifies what skills, knowledge, and ways of working are needed for each job. This helps the company reach its goals by ensuring that everyone has the right abilities. Furthermore, it facilitates targeted personal growth and development, enabling employees to identify and bridge competency gaps, visualize career trajectories, and achieve a sense of personal mastery. By incorporating organizational values into our competency frameworks, we improve ethical conduct, ensure that everyone's work contributes to our shared goals, and build a more transparent and purpose-driven organizational culture. Eventually, competency mapping promotes collaborative teamwork by highlighting collective strengths and fostering mutual respect, leading to enhanced emotional engagement and organizational cohesion.
title: Improved Discharge Capacity of Zinc Particles by Applying Bismuth-Doped Silica Coating for Zinc-Based Batteries Batteries
Creators: name: Michlik, Tobias
name: Rosin, Andreas
name: Gerdes, Thorsten
name: Moos, Ralf
Publisher: name: University of Bayreuth
Year: 2019
Subjects: subject: 620

description: Corrosion and discharge behavior of battery-grade zinc particles coated with a silica layer doped with bismuth was investigated and compared with untreated zinc powder. Electrochemical investigations were carried out in half-cell configuration. The electrolyte was 6 M KOH in excess. Coated zinc particles provided a discharge capacity of 737 mAh g−1 (89.9% DoD) versus 633 mAh g−1 (77.2% DoD) of untreated zinc particles after a dwell time of 1 h in KOH. The silica coating reduced the direct contact of the zinc surface with the electrolyte and thus minimized the hydrogen evolution reaction, which led to an increased discharge capacity. Additionally, bismuth doping enhanced conductivity within the silica coating and increased zinc utilization. Those coated zinc particles inhibited corrosion, i.e., corrosion efficiency reached 87.9% compared to uncoated zinc. Additionally, the coating achieved a capacity retention of 90.9% (670 mAh g−1) after 48 h dwell time in 6 M KOH. The coatings were prepared by sol-gel technology and characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffractometry (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and Brunauer-Emmett-Teller (BET) surface determination.
Σχεδιασμός Διαδικτυακής Κοινότητας Πρακτικής Η Εκπαιδευτική Κοινότητα «STEAM-Robots»
Creators: name: Milakis, Emmanouil
Publisher: name: figshare
Year: 2022
Subjects: subject: 130306 Educational Technology and Computing
subject: FOS: Educational sciences
subject: Education
subject: 130106 Secondary Education
subject: 130313 Teacher Education and Professional Development of Educators

description: This paper describes the design of an online community of practice for educators and have as a common goal the promotion of STEAM and Robotics Education and the creation of corresponding interdisciplinary educational material. Through the above prism are presented the characteristics and theoretical principles of a community of Practice and their respective models of analysis. At the same time, the possibility of utilizing modern internet tools for the technical support of such an effort is being explored.
A Novel Approach for Omic and Electronic Health Record Using Big Data Analytics for Precision Medicine
Creators: name: D.H, Shivalingappa
name: Shivprakash, Prof.
name: Burkpalli, Dr. Vishwanath. C.
Publisher: name: figshare
Year: 2022
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: Rapid advances of high-throughput innovations and wide selection of electronic health records (EHRs) have prompted quick amassing of–omic and EHR information. These voluminous complex information contain plentiful data for exactness drug, and huge information investigation can concentrate such information to enhance the nature of medicinal services. Strategies: In this paper, I present – omic and EHR information attributes, related difficulties, and information investigation counting information preprocessing, mining, and displaying. Results: To exhibit how enormous information investigation empowers accuracy prescription, I give two contextual investigations, including recognizing illness biomarkers from multi-omic information and consolidating omic data into EHR. End: Big information investigation can address – omic and EHR information challenges for change in perspective toward accuracy drug. Essentialness: Enormous information examination understands omic and EHR information to enhance medicinal services result. It has dependable societal effect .
Modeling Clustered Data with Very Few Clusters
Creators: name: McNeish, Daniel
name: Stapleton, Laura M.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Small-sample inference with clustered data has received increased attention recently in the methodological literature, with several simulation studies being presented on the small-sample behavior of many methods. However, nearly all previous studies focus on a single class of methods (e.g., only multilevel models, only corrections to sandwich estimators), and the differential performance of various methods that can be implemented to accommodate clustered data with very few clusters is largely unknown, potentially due to the rigid disciplinary preferences. Furthermore, a majority of these studies focus on scenarios with 15 or more clusters and feature unrealistically simple data-generation models with very few predictors. This article, motivated by an applied educational psychology cluster randomized trial, presents a simulation study that simultaneously addresses the extreme small sample and differential performance (estimation bias, Type I error rates, and relative power) of 12 methods to account for clustered data with a model that features a more realistic number of predictors. The motivating data are then modeled with each method, and results are compared. Results show that generalized estimating equations perform poorly; the choice of Bayesian prior distributions affects performance; and fixed effect models perform quite well. Limitations and implications for applications are also discussed.
title: 20 years of HIV science
Creators: name: Leibowitch, Jacques
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Extrait de Nature Medicine, vol. 9, 2003, no 7(juillet).
description: Source: http://www.calames.abes.fr/pub/ms/Calames-2019311113569666
description: created: start=2003-07;end=2003-10
High-resolution morpho-bathymetry of the Gulf of Naples, Eastern Tyrrhenian Sea
Creators: name: Passaro, Salvatore
name: Tamburrino, Stella
name: Vallefuoco, Mattia
name: Gherardi, Serena
name: Sacchi, Marco
name: Ventura, Guido
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: We present a high-resolution bathymetric map of the Gulf of Naples (Italy), which is surrounded by the two main volcanic complexes of Mt. Somma-Vesuvius and Phlegrean Fields. The morphology is obtained from swath bathymetric in a Digital Terrain Model with a 5 m grid cell size. Bathymetric data display the main seafloor morphologies with a resolution never obtained before. These morphologies include the Ammontatura and Dohrn Canyons, the Penta Palummo, Nisida, Miseno and Banco della Montagna banks, and the bathymetric features of the submerged sector of the Somma-Vesuvius volcano. Overall, a prevailing volcanic nature characterizes the seafloor morphologies located in the northern sector, while the southern one is dominated by sedimentary features. The Final Map could be useful for the evaluation of the volcano-related hazards in the area.
Geology of the Raditladi quadrangle, Mercury (H04)
Creators: name: Mancinelli, Paolo
name: Minelli, Francesco
name: Pauselli, Cristina
name: Federico, Costanzo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Plant Biology

description: In this work, we present a 1:3,000,000-scale geologic map of the Raditladi quadrangle (H04) of Mercury. The area covers nearly 7% of the entire planet and encompasses several features of interest such as the Caloris basin, the Raditladi basin, hollow clusters and volcanic features. The mapping took advantage of the data produced during MESSENGER's orbital phase. The mapped deposits include impact-related units observed at several scales from the Caloris basin to the secondary crater chains. The Smooth Plains unit covers the majority of the area, mantling the older Intercrater Plains and Bright Intercrater Plains units. Results show that the emplacement of all the main units and the Caloris impact event, representing the main geologic events in the quadrangle, were concentrated between 3.96 and 3.72 Ga. After this intense phase, the geologic framework was modified only by local events such as impact craters and hollow formation. This map is among the first products for the detailed geologic characterization of Mercury at such a scale. It will contribute as a constraint and a support for both further local investigation and mapping, and targeting of the forthcoming BepiColombo ESA/JAXA joint exploration mission to Mercury.
Automatic scoring of singing voice based on melodic similarity measures
Creators: name: Molina, Emilio
Publisher: name: Zenodo
Year: 2012
Subjects: singing
skill
assessment
evaluation
transcription
scoring

description: A method for automatic assessment of singing voice is proposed. Such method quantifies in a meaningful way the similarity between the user performance and a reference melody. A set of melodic similarity measures comprising intonation and rhythmic aspects have been implemented for this goal. Such measure implement different MIR techniques, such as melodic transcription or score alignment. The reference melody is a professional performance of the melody, but the original score could be also used with minor changes in the schema. In a first approach, only intonation, rhythm and overall score have been considered. A polynomial combination of the similarity measures output are finally used to compute the final score. The optimal combination has been obtained by data fitting from a set of scores given by real musicians to different melodies. The teacher criteria is specially well modelled for pitch intonation evaluation. The general schema is also applicable to more complex aspects such as dynamics or expressiveness if some other meaningful similarity measures are included.
The Influence of Religion and Human Development on the Participation of Women in the Labor Force: A Case of the African Continent
Creators: name: Olowolagba, Zainab Tofunmi
Publisher: name: Manara - Qatar Research Repository
Year: 2024
Subjects: classificationCode: 50
subject: Philosophy and religious studies

description: The African continent has low female participation compared to other regions of the world. This study aims to find the influence of religion and human development on the participation of women in the labor force in Africa. The data used in this study are sourced from the World Development Indicator and the Organization for Islamic Countries for all 54 African countries from 1995 to 2019 (25 years). This study used the quantitative method. Stata application software is used in data analysis. Pooled Ordinary Least Square (O.L.S.) regression technique and Random effects were used to come about results. This study revealed that the components of the Human Development Index (HDI) influence women’s participation in the labor force, and education especially. Our results show a positive relationship between the components of HDI and female participation and a negative relationship between religion and female labor participation, but a positive relationship is observed when religion interacts with education (proxied with years of schooling). Since education is a massive contributor to the willingness of women to participate in the labor force, we can recommend that the Governments of Africa pursue policies and strategies where women have greater access to and are grossly included in education programs.
Description des initiatives pour prévenir et traiter l'intimidation scolaire dans Jes provinces canadiennes
Creators: name: Beaudoin, Huguette
name: Roberge, Ginette
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: This paper is based on a research project in progress (Roberge & Beaudoin, submitted), and maintains the objective of studying the content of bullying prevention and intervention policies in Canadian provinces and territories. A content analysis of these policies has been conducted in order to determine to which extent they adhere to promising anti-bullying practices identified in extant research. An instrument created and validated by Smith, Smith, Osborne & Samara (2008) and Roberge & Beaudoin (submitted) was utilized for the analysis of these policies. The results presented discuss the strengths and limitations of proficient bullying prevention and intervention practices that have been established in Canadian provinces and territories.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 46 No 1 (2012)
Inclusive Collaboration with Families of Children with Autism Spectrum Disorders (ASD): Perceptions of Families, Pre-Service and In-Service Level Teachers
Creators: name: Fallon, Moira
name: Zhang, Jie
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: In the social sciences, collaboration among teams is often a requirement. However, integrating collaboration with the principles of inclusion seems to be restricted to the field of education. Collaboration based on inclusive practices improves the diverse quality of team communication, problem solving, and decision making. In the field of education, educators have the primary responsibility for engaging all students in the learning process and actively involving them in the classroom setting and with the course content. Inclusive collaborators understand that their beliefs, values, attitudes, and behaviors set the tone for each decision. They know that all team members can learn across differences and they are determined to reach all. We provide a timely investigation into the needs of families of children with autism for collaboration. The results illustrate the differing perception of essential collaboration skills among pre- and in service level professionals and families. This demonstrates a need for continuity in collaboration skills of professionals as they move from pre-service into in-service levels in their interactions with families of children with autism. The results of such critical efforts are persons within an organization who possess the ability to work together across their differences.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 46 No 1 (2012)
Degradation products of mangiferin by gamma irradiation with inhibitory effects on NO production
Creators: name: Cheorun Jo
name: Yoon, Kyung Young
name: Jang, Eun Jin
name: Kim, Tae Hoon
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: The xanthone glucoside mangiferin (1) was converted by γ-irradiation into three new compounds, mangiferdiol (2), mangiferinol (3), and isomangiferinol (4). The new compound 2 containing two hydroxymethyl groups instead of a ketone moiety exhibited significantly improved inhibitory activity against nitric oxide production in lipopolysaccharide-stimulated RAW264.7 cells with IC50 value 47.1 ± 1.7 μM, compared to the mother mangiferin.
title: 03_0911
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Are Academies Meeting Government Achievement Targets? A systematic appraisal exploring educational achievement in Academies in England from 2002-2010
Creators: name: Cole, Andrea
name: Barlow-Meade, Linda
name: Littlefair, David
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: This study focuses upon the Academies Programme in England from 2002-2010. From one perspective the Academies Programme is a straightforward attempt to increase educational achievement. And yet, from its inception the Programme has been controversial, principally because of a private ownership ideology being introduced into state schools. The findings of this study suggest three areas of significance. Firstly, evidence suggests that Academies per se cannot be said to improve academic achievements in line with government expectations. Even where an increase has been shown, it usually refers to schools that were already performing well before becoming Academies. Secondly, alternative evidence shows that Academies do appear to be reaching government achievement targets. The problem here is that the data can be interpreted as flawed, because much of the research is government commissioned and it is in their interests to arrive at 'improvements'. The third strand is concerned with the time frame under investigation. Between 2002- 2007, schools which became Academies often had a diminishing Free School Meals (FSM) intake and an increasing number of excluded pupils whose performance was poor, thus affecting a school's overall grades.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 46 No 1 (2012)
Thermosensitive magnetic liposomes with doxorubicin cell-penetrating peptides conjugate for enhanced and targeted cancer therapy
Creators: name: Lin, Wen
name: Xiangyang Xie
name: Yanfang Yang
name: Xudong Fu
name: Liu, Hong
name: Yang, Yang
name: Jianping Deng
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: To specifically deliver cytotoxic drug to tumor cells and enhance cellular uptake is the key for effective cancer therapy. In this paper, we described a novel drug targeting system, which is designed to combine features of biological (cell-penetrating peptides, CPPs) and physical (magnetic) drug targeting for use in the magnetic hyperthermia-triggered release. A doxorubicin–CPPs conjugate (DOX-CPPs) was loaded into thermosensitive magnetic liposomes (TSMLs) (DOX-CPPs/TSMLs), and in vitro DOX-CPPs thermosensitive release activity, anti-proliferation effect, in vivo targeted delivery as well as in vivo antitumor activity were determined. The results demonstrated that the DOX-CPPs/TSMLs showed good physicochemical properties, effective anti-proliferation effect in MCF-7 cells in vitro. Additionally, in vivo study, DOX-CPPs/TSMLs under AC magnetic field displayed superior in vivo targeted delivery efficacy, antitumor efficacy in an MCF-7 xenograft murine model. In conclusion, the application of DOX-CPPs/TSMLs under AC magnetic field may provide a strategy for the selective and efficient delivery of drug.
Metal-catalyzed oxidation of 2-alkenals generates genotoxic 4-oxo-2-alkenals during lipid peroxidation
Creators: name: Nuka, Erika
name: Tomono, Susumu
name: Ishisaka, Akari
name: Kato, Yoji
name: Miyoshi, Noriyuki
name: Yoshichika Kawai
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Lipid peroxidation products react with cellular molecules, such as DNA bases, to form covalent adducts, which are associated with aging and disease processes. Since lipid peroxidation is a complex process and occurs in multiple stages, there might be yet unknown reaction pathways. Here, we analyzed comprehensively 2′-deoxyguanosine (dG) adducts with oxidized arachidonic acid using liquid chromatography–tandem mass spectrometry and found the formation of 7-(2-oxo-hexyl)-etheno-dG as one of the major unidentified adducts. The formation of this adduct was reproduced in the reaction of dG with 2-octenal and predominantly with 4-oxo-2-octenal (OOE). We also found that other 2-alkenals (with five or more carbons) generate corresponding 4-oxo-2-alkenal-type adducts. Importantly, it was found that transition metals enhanced the oxidation of C4-position of 2-octenal, leading to the formation of OOE-dG adduct. These findings demonstrated a new pathway for the formation of 4-oxo-2-alkenals during lipid peroxidation and might provide a mechanism for metal-catalyzed genotoxicity. 4-Oxo-2-alkenals, which are highly reactive to nucleosides, are generated through metal-catalyzed oxidation of corresponding 2-alkenals during lipid peroxidation.
Storytelling in University Education: Emotion, Teachable Moments, and the Value of Life
Creators: name: Woodhouse, Howard
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: Teaching as a process of storytelling allows faculty to reach out to students' emotions, breathing life into the ideas that are being taught and learned. Storytelling among indigenous peoples emphasizes the importance of balanced relationships with the land, with all living creatures, and with the cosmos. It serves different functions in other societies that can also enhance teaching and learning. Alfred North Whitehead's account of emotions is relevant to the learning process and to teachable moments better understood as learning opportunities that enhance the value of students' lives. I provide an example of such a learning opportunity in which one of my students experienced an energetic connection with her colleagues as a living community. Teachable moments and storytelling can strengthen students' range of comprehension, their imaginative and aesthetic appreciation, as well as their growing capacity to learn. True stories - those based on a process which more coherently and inclusively takes into account life coordinates - enable students and faculty to critique the money sequence of value of the global market. A pedagogy based on true storytelling opens up spaces for the expression of different groups whose voices have been marginalized.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 45 No 3 (2011)
Border Bureaucracies: A Literature Review of Discretion in Migration Control
Creators: name: Borrelli, Lisa Marie
name: Hedlund, Daniel
name: Johannesson, Livia
name: Lindberg, Annika
Publisher: name: nccr – on the move
Year: 2023

description: This literature review summarizes findings from 63 articles published between 2001 and 2020 that study discretion of frontline workers at migration control. The results demonstrate that discretionary practices in various migration control situations (e.g., border zones, migration agencies, courts, public welfare services, and detention centers) are widespread but share common patterns. Frontline workers’ racialized prejudices and perceptions of migrant deservingness were the most dominant patterns found in the data, although there were some disagreements about which were most influential. Discretion of frontline workers was described as foremost detrimental to migrants, as it amplified the migrants’ vulnerable situations, even if it occasionally could increase individual migrants’ room for agency and strategic maneuvering. Contrary to the assumption underpinning the control gap-thesis in immigration policy literature that governments’ capacity to control migration is hampered by the significant discretion at the frontlines, many studies in our sample describe how governments shape the discretionary practices of frontline workers through informal, subtle, and opaque governing strategies. These informal governing strategies enable central governments to deflect responsibility for discriminatory and inhumane policy outcomes.
Croyances mathématiques chez des futurs maitres au primaire: une activité réflexive
Creators: name: D'Entremont, Yvette
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: II est bien documenté que les croyances que l'on a des mathématiques influencent l'enseignement et l'apprentissage de cette matière. Cet article est une réflexion, suscitée par la question d'une étudiante «Mais, quelle est la bonne méthode?» sur Jes croyances mathématiques des étudiants dans un cours de didactique au primaire. Les résultats indiquent qu'il est important d'aborder ces croyances et d'eéaborer des situations pédagogiques de réflexion dans la formation des maitres au primaire.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 45 No 3 (2011)
What Do We Mean by Literacy? Implications for Literacy Education
Creators: name: Lee, Cheu-Jey
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: Literacy education has been of continuous interest to educators and researchers for decades. This paper is concerned with a critical examination of two interrelated aspects of literacy education: (a) the meaning of literacy and (b) its implications for literacy education. It begins with a discussion of the meaning of literacy by reviewing the research literature. It shows that literacy is not singular but multiple and is closely tied to social practices. Then the discussion switches to how literacy as multiple social practices relates to literacy education. This paper ends with a call for a topsy-turvy look at the purpose of literacy education and with a challenge to literacy educators to reflect on their practices accordingly.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 45 No 3 (2011)
Recovering Ancient Wisdom and the 2010 Albertan Education Reforms
Creators: name: Steel, Sean
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: This paper critically examines the Government of Alberta's 2010 "Inspiring Education" Report in light of insights drawn from ancient philosophy and some of the world's wisdom traditions. The paper challenges the contention made throughout the Report that its recommendations are "transformational," for while they aim at securing greater future successes for students throughout Alberta, they do not contribute to the cultivation of wisdom whereby any such successes might be enjoyed; rather, evidence in the text of the Report suggests that the vision it espouses will serve to discourage the pursuit of wisdom, particularly in the Committee's demands for accountability and relevance aimed at innovation. Readers are invited to consider what an education-for-wisdom would look like. It is suggested that educational reforms truly concerned with such a "transformation" would need to include time throughout the day for teachers and students to cultivate their contemplative or noetic capacities in an atmosphere of leisure or schole.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 45 No 3 (2011)
Reverberations of the Historic Culture Clash Between Incoming European Nations and Resident First Nations Continue to Linger
Creators: name: Friesen, John W.
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: This paper will argue that the root cause for many contemporary misunderstandings between Canada's First Nations and dominant society originated at the time of First Contact with incoming Europeans-French and English. Subsequent government inaction and lack of concern on the part of the public have allowed these misunderstandings to prevail. The result is that Canada's Aboriginal peoples have fallen behind and continued to experience a lower socioeconomic standard of living. A summary and analysis of what Aboriginal leaders and writers are saying about the injustices their people have suffered is discussed. These writers offer hope to rectify the situation through education.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 46 No 1 (2012)
Risk-based approach to developing a national residue sampling plan for testing under European Union regulation for veterinary medicinal products and coccidiostat feed additives in domestic animal production
Creators: name: Danaher, Martin
name: Shanahan, Conor
name: Butler, Francis
name: Evans, Rhodri
name: O’Sullivan, Dan
name: Glynn, Denise
name: Camon, Tim
name: Lawlor, Peadar
name: O’Keeffe, Michael
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: A ranking system for veterinary medicinal products and coccidiostat feed additives has been developed as a tool to be applied in a risk-based approach to the residue testing programme for foods of animal origin in the Irish National Residue Control Plan (NRCP). Three characteristics of substances that may occur as residues in food are included in the developed risk ranking system: Potency, as measured by the acceptable daily intake assigned by the European Medicines Agency Committee for Medicinal Products for Veterinary Use, to each substance; Usage, as measured by the three factors of Number of Doses, use on Individual animals or for Group treatment, and Withdrawal Period; and Residue Occurrence, as measured by the number of Non-Compliant Samples in the NRCP. For both Number of Doses and Non-Compliant Samples, data for the 5-year period 2008–12 have been used. The risk ranking system for substances was developed for beef cattle, sheep and goats, pigs, chickens and dairy cattle using a scoring system applied to the various parameters described above to give an overall score based on the following equation: Potency × Usage (Number of Doses + Individual/Group Use + Withdrawal Period) × Residue Occurrence. Applying this risk ranking system, the following substances are ranked very highly: antimicrobials such as amoxicillin (for all species except pigs), marbofloxacillin (for beef cattle), oxytetracycline (for all species except chickens), sulfadiazine with trimethoprim (for pigs and chickens) and tilmicosin (for chickens); antiparasitic drugs, such as the benzimidazoles triclabendazole (for beef and dairy cattle), fenbendazole/oxfendazole (for sheep/goats and dairy cattle) and albendazole (for dairy cattle), the avermectin ivermectin (for beef cattle), and anti-fluke drugs closantel and rafoxanide (for sheep/goats); the anticoccidials monensin, narasin, nicarbazin and toltrazuril (for chickens). The risk ranking system described is a relatively simple system designed to provide a reliable basis for selecting the veterinary medicinal products and coccidiostat feed additives that might be prioritised for residue testing.
Providential Deism, Divine Reason, and Locke's Educational Theory
Creators: name: Joldersma, Clarence W.
Publisher: name: Journal of Educational Thought / Revue de la Pensée Educative
Year: 2018

description: This essay uses Charles Taylor's recent description of secularity to rethink an important historical example of the relation among religion, reason, and education. Locating Locke's educational theory in the historical period that Taylor calls providential deism, the article suggests that Locke's idea of good education, namely, moving students to follow the dictates of reason alone, cannot proceed without two related features of reason, its infallibility and its inherent attractiveness. These two, but especially the latter give reason a transcendent if not divine status, akin to Providential grace. The article claims that this not only gives education a central role in society's improvement, but it challenges Taylor's claim that Providential deism is an eclipse of grace. It does so by arguing that in this transition Providential grace comes in the form of reason's inherent attractiveness and that good education is key to expose students to this inherent attractiveness of reason.
description: Journal of Educational Thought / Revue de la Pensée Educative, Vol 45 No 2 (2011)