cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Display and analysis of three dimensional experimental electrocardiographic data
Creators: name: Seeger, Anthony Rutledge
Publisher: name: University of Utah
Year: 2012

description: The fundamental problem of electrocardiography is to interpret body surface voltage distributions induced by cardiac generated currents. As a step towards understanding this process further, experimental potential data were collected from 600 electrode sites on and within a tank of electrolyte in which an isolated, perfused, canine heart was immersed. Programs were written to display potentials in horizontal, vertical, and circular formats. Studies on the effect of distance from the source to surfaces in the volume were carried out through the use of eigenvector analysis. Through use of a cross covariance transformation, analysis of the ability to represent data on one surface by the eigenvectors of another surface was conducted.  Results include development of programs to display and analyze data from three dimensional electrode arrays in two dimensional graphical formats. Results from the studies of distance effects include analysis of the information content of the primary eigenvectors and their associated eigenvalues. It was found that the error could be decreased from 20 percent to 12 percent by increasing the number of eigenvalues used to recreate the surface from 3 to 5.
Brief an [Johann III Bernoulli]
Creators: name: Fontana, Gregorio
Publisher: name: [s.n.]
Year: 1776

description: von Greg[orio] Fontana
description: 6 Zeilen Autograph
description: Mit Spuren von einer roten Oblate
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Druck: Astron. Jahrbuch od. Ephemeriden f. 1779, II, S.27-33
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
description: L Ia 692:Bl.40-41
Brief an [Johann III Bernoulli]
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1781

description: von N[iklaus] Fuss
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Druck: N. Mém. Acad. Berlin, 1781, H.31
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
The disruption model of inspiration: toward a general model of "being inspired to act"
Creators: name: Smith, Isaac H.
Publisher: name: University of Utah
Year: 2014
Subjects: Ethics
Inspiration
Leadership
Morality
Motivation
Prosocial behavior

description: For many-from prophets and poets to athletes and activists-experiencing inspiration is a fundamental part of the human condition. Specifically, inspiration can be a powerful tool in motivating people to act morally, help other people, and become their best selves. However, despite the power of inspiration to help people fulfill their potential, surprisingly little is known about when and why individuals are actually inspired to action. Drawing from schema incongruity theory and recent conceptualizations of inspiration as a psychological construct, I develop and test a general model of being inspired to act (the disruption model of inspiration). I assert that individuals will be more likely to experience inspiration-that is, feel inspired to act-to the extent that an evoked potential action is perceived as (1) disruptive to the continuity of their current mental schemas (i.e., it forces them to think about things differently), (2) relevant to the fulfillment of their core human motives (i.e., agency, communion, and coherence), and (3) attainable (i.e., they believe they can successfully accomplish the action or actualize the possibility). While this model has implications for theory and research on leadership, social influence, motivation, and other topics of organizational import, I focus on the role of inspiration in the moral domain-specifically related to prosocial behavior. Accordingly, I examine the human experience of inspiration in a survey of U.S. adults, an online experiment, and a field experiment in a Fortune 100 company.
Brief an J[ohann] III Bernoulli
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1780

description: von [Niklaus] Fuss
description: Mit rotem Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Scybalocanthon adisi Silva and Valois 2019
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Scybalocanthon
Scybalocanthon adisi

description: § Scybalocanthon adisi Silva and Valois, 2019
Scybalocanthon adisi Silva and Valois 2019: 310 (Brazil (NA))
Brazil (NA): Silva and Valois 2019: 310 (NA). Other: Silva and Valois 2019: 310 (Ecuador).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 81, DOI: 10.5281/zenodo.3678492
Additional file 10 of Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients
Creators: name: D’Amato, Alfonsina
name: Mannelli, Lorenzo Di Cesare
name: Lucarini, Elena
name: Man, Angela L.
name: Gall, Gwenaelle Le
name: Branca, Jacopo J. V.
name: Ghelardini, Carla
name: Amedei, Amedeo
name: Bertelli, Eugenio
name: Regoli, Mari
name: Pacini, Alessandra
name: Luciani, Giulia
name: Gallina, Pasquale
name: Altera, Annalisa
name: Narbad, Arjan
name: Gulisano, Massimo
name: Hoyles, Lesley
name: Vauzour, David
name: Nicoletti, Claudio
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 10. Metabolome-proteome correlation (Pearson). Results for Fatty acids C6 onwards .
Additional file 1 of Preoperative forced expiratory volume in one second and postoperative respiratory outcomes in nonpulmonary and noncardiac surgery: a retrospective cohort study
Creators: name: Mizota, Toshiyuki
name: Hamada, Miho
name: Hirotsu, Akiko
name: Dong, Li
name: Matsukawa, Shino
name: Takeda, Chikashi
name: Egi, Moritoki
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Supplemental Table 1. Definitions of the collected variables.
Antifeedant and ovicidal activities of a new cassane and other compounds from Caesalpinia welwitschiana Oliv. and Caesalpinia bonduc L. against Tuta absoluta (Lepidoptera: Gelechiidae)
Creators: name: Essoung, Flaure Rosette Ehawa
name: Mba’ning, Brice Mitterant
name: Tcho, Alain Tadjong
name: Chhabra, Sumesh Chander
name: Mohamed, Samira Abuelgasim
name: Lenta, Bruno Ndjakou
name: Ngouela, Silvere Augustin
name: Tsamo, Etienne
name: Hassanali, Ahmed
name: Cox, Russell John
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Methanolic extracts of liana of Caesalpinia welwitschiana and leaves of C. bonduc were found to possess moderate antifeedant and ovicidal activities against Tuta absoluta. Bioassay-guided isolation of constituents from the most active fraction of C. welwitschiana led to the identification of four known compounds [isobonducellin 1a and bonducellin 1 b, intricatinol 2, (-)-epigallocatechin-3-O-gallate 4] and one new constituent [welwitschianic acid 3]. The most active fraction of C. bonduc afforded two known constituents neocaesalpin L 5 and neocaesalpin A 6. The isolated structures were elucidated on the basis of their MS, UV, IR and 1 & 2 D NMR spectra and by comparison with literature data. Compounds 2, 4-6 were showed antifeedant and ovicidal properties against T. absoluta, some comparable to that of azadirachtin at 50, 100 and 200 ng/µl. Overall, the present study, conclude that the two species of the plant could be a promising source of eco-friendly botanical constituents.
Additional file 1 of Supporting a review of the benefits package of the National Health Insurance Scheme in Ghana
Creators: name: Vellekoop, Heleen
name: Odame, Emmanuel
name: Ochalek, Jessica
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 1. S1. Details of literature search on DALYs avoided. S2. References of cost-effectiveness studies included. S3. Data sources used to calculate annual population in need. S4. Calculating the annual budget available for claims reimbursement. S5. Calculating reduced healthcare demand. S6. Details on the sensitivity analysis. S7. Calculating the budget impact of implementing all interventions under consideration. S8. Co-payments for interventions in coinsurance packages. S9. Outcome tables for the sensitivity analysis.
Brief an [Johann III Bernoulli]
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1782

description: von N[iklaus] Fuss
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Brief an [Johann III Bernoulli]
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1781

description: von [Niklaus] Fuss
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Brief an J[ohann] III Bernoulli
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1782

description: von Niklaus Fuss
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Individual and dyadic appraisals of pain severity and control and patient and spouse adjustment to chronic pain across the lifespan
Creators: name: Skinner, Michelle A
Publisher: name: University of Utah
Year: 2012
Subjects: Aging
Pain
Spouses

description: Chronic pain impacts the physical, psychological, behavioral, and relational landscape of both the patient and the spouse. The study examined how both patient and spouse appraisals of pain severity and control were associated with adjustment for marital couples of varying ages across adulthood. Fifty couples where one member had chronic back pain completed measures of appraisals of pain and controllability and adjustment. Results revealed that individual patient and spouse appraisals of higher pain were associated with patient psychological distress, higher pain behavior reports by both patients and spouses, and higher reported spouse criticism for patients. For individual control appraisals, lower patient and spouse control appraisals were associated with lower  psychological distress for patients, lower pain behavior reports by patients and spouse, and higher patient reported criticism. Dyadic effects were also observed. Higher patient pain was associated with higher spouse reports of support and criticism when spouses also appraised high pain. Lower patient appraisals of control were associated with patient reports of lower spouse support when spouse appraised higher control. We found  interactions with age suggesting that higher patient pain was associated with higher patient psychological distress and lower patient pain appraisals were associated with  lower spouse reports of supportive responses in younger couples.
Bisbenzylisoquinoline alkaloids of Cissampelos sympodialis with antiviral activity against dengue virus
Creators: name: da Silva, Poliana G.
name: Fonseca, Aventino H.
name: Ribeiro, Malu P.
name: Silva, Taizia D.
name: Grael, Cristiane F. F.
name: Pena, Lindomar J.
name: Silva, Tania M. S.
name: de J. Oliveira, Eduardo
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology

description: A number of bisbenzyilisoquinoline alkaloids have been previously isolated from Cissampelos sympodialis (Menispermaceae). The tertiary alkaloid fraction of the rhizomes (TAFrz) was prepared and the major alkaloid warifteine was isolated. Five TAFrz subfractions in addition to warifteine were tested against Dengue virus (DENV). We then used an epithelial (Vero) cell line to evaluate the cytotoxicity and effective concentrations of the samples against DENV. All TAFrz subfractions were active, but subfraction 6 (a mixture of the alkaloids methylwarifteine and warifteine) in particular showed a promising antiviral effect against DENV-2 with an IC50 of 2.00 µg/mL and a selectivity index (SI) of 10.74. Warifteine was the second most active sample and had an IC50 of 8.13 µg/mL and SI = 10.94. The antiviral activity of the samples compared favorably with that of 6-methylmercaptopurine riboside (IC50 = 7.31 µg/mL and SI = 11.8). These results suggest that bisbenzylisoquinoline alkaloids may prove interesting leading antiviral compounds.
Scybalocanthon cyanocephalus
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Scybalocanthon
Scybalocanthon cyanocephalus

description: Scybalocanthon cyanocephalus (Harold, 1868)
Canthon cyanocephalus Harold 1868a: 53 (French Guiana, “Guianas,” Venezuela)
Distribution. Suriname: MHCN - NEW COUNTRY RECORD (Suriname, Sipaliwini, Puketi, (4°07′30″N, 54°37′30″W). 14/ 16-VII-2013. A. J. Hielkema. On topside of leaves in forest.); NZCS; RMNH. French Guiana: Harold 1868a: 53 (as Canthon cyanocephalus); Gillet 1911b: 29 (as Canthon cyanocephalus); Balthasar 1939e: 191 (as Canthon cyanocephalus); Blackwelder 1944: 199 (as Canthon cyanocephalum); Pereira and Martínez 1956b: 119; Vulcano and Pereira 1964: 637; Silva and Valois 2019: 319. “Guianas”: Harold 1868a: 53 (as Canthon cyanocephalus); Blackwelder 1944: 199 (as Canthon cyanocephalus). Brazil (NA): Blackwelder 1944: 199 (as Canthon cyanocephalum); Pereira and Martínez 1956b: 119; Vulcano and Pereira 1964: 637; Vaz-de-Mello 2000: 195 (as S. cyanocephalum); Silva and Valois 2019: 319 (NA). Venezuela (EO): Blackwelder 1944: 199 (as Canthon cyanocephalum); Vulcano and Pereira 1964: 637; Ferrer-Paris et al. 2013: 110 (EO); Silva and Valois 2019: 319 (EO). Other: Silva and Valois 2019: 319 (Trinidad and Tobago).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 81, DOI: 10.5281/zenodo.3678492
Probing the topoisomerase II mechanism using mutants and inhibitors
Creators: name: Morris, Shayne Kenneth
Publisher: name: University of Utah
Year: 2012
Subjects: ATP hydroysis
DNA transport
Topoisomerase
Biochemistry
Molecular Biology

description: Type II DNA topoisomerases function as molecular motors, utilizing the energy in ATP hydrolysis to pass one DNA duplex through an enzyme-mediated double-stranded break in a second DNA. The enzyme uses a complex mechanism, somehow coupling DNA cleavage/relegation, and transport of a second DNA segment to sequential ATP hydrolysis. In order to define further the entire topoisomerase II mechanism, site directed mutagenesis and topoisomerase II inhibitors were used as mechanistic probes. Additionally, these studies analyzed how the drugs, etoposide and ICRF-193, interrupt the topoisomerase II reaction cycle.  The coupling between ATP hydrolysis and DNA cleavage/relegation reactions was studied using mutant enzymes that cannot cleave DNA and etoposide, an anticancer drug that blocks DNA relegation. Blocking DNA cleavage prevents enzyme binding to the transported DNA segment, and reduces the rate of hydrolysis of the first ATP. Blocking DNA relegation inhibits the multiple turnover ATPase and DNA transport reactions by hindering either the first ADP release or the second ATP hydrolysis. These results suggest that DNA cleavage allows the transported DNA segment to bind, stimulating ATP hydrolysis. Additionally, DNA relegation occurs before the second ADP is released, keeping the enzyme in the closed form until the DNA break is resealed.  ICRF-193 is an experimental drug that locks topoisomerase II in a closed, intermediate conformation. Surprisingly, this intermediate form continues to hydrolyze ATP, albeit at a reduced rate. Results of rapid kinetic experiments indicate that this drug binds to the enzyme after both ATP have been hydrolyzed, but before the second ADP is released. Together with the cleavage mutant and etoposide data, these results have led to a more complete understanding of the topoisomerase II mechanism.
Brief an [Johann III Bernoulli]
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1780

description: von N[iklaus] Fuss
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Two aspects of computerized patient history that improve bedside pulmonary diagnosis
Creators: name: Rich, Tracy
Publisher: name: University of Utah
Year: 2012
Subjects: Medical records - Data processing
Lungs - Diseases - Diagnosis

description: This thesis project involves two aspects of research in the area of diagnostic decision making of cardio-pulmonary disease.  This study is concerned with a set of logic frames that have been written to detect a group of 41 pulmonary and cardiology disease.  When the diagnostic frames were first developed, there were 58 frames for 29 diseases.  There were two frames for each disease.  The first dealt with patient history, and the second dealt with physical exam, laboratory, and radiology findings.  The a posteriori probabilities generated by the history frames are used as the entrant a priori probabilities of the corresponding clinical data frames.  The history frames have evolved to include more than the original 29 disease states, whereas the clinical data frames have continued to include only the original 29 diseases.  The first part of the study deals with the problem of gathering a computerized patient history that could then be available for use by the pulmonary diagnostic history frame.  Two different computerized data gathering techniques, that captured a patient history directly from the patient  using a terminal mounted near the bedside, were compared.  One of the collection modes is hierarchical questionnaire that consists of a conditional branching set of fixed frames (GQAP).  The other history gathering program utilized DDA, a decision-driven data acquisition system.  The goal of this project is to determine if there is a measurable difference between the two data collection modes in 1) time to complete, 2) number of questions asked, or 3) accuracy of decision made form the entered data.  Physical exam data by the physician into a computer terminal were the next type of data that was scheduled to be collected at the patient's bedside.  These data would then be available for utilization by the clinical data frames that diagnose cardio-pulmonary diseases.  Before the collection of physical exams began, the Bayesian statistics used in the clinical data frames for chest X-ray findings needed to be revised.  It was felt that revising the statistics for the radiology finding, using a data base of actual patients who had entered LDS Hospital, would create a better set of statistics that the statistics that were originally estimated by the medical experts.  The second part of this study involves the revision of chest X-ray finding in the pulmonary clinical data frames, and the evaluation of the effect the revised statistics had  upon the accuracy of the diagnostic system.
Brief an [Johann III Bernoulli]
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1781

description: von Niklaus Fuss
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Graffiti, art, and identity: exploring Gajin Fujita's Hood Rats
Creators: name: Guiley, Patricia Kathleen
Publisher: name: University of Utah
Year: 2015
Subjects: Gajin fujita
Global contemporary
Graffiti
Identity
Street art
Urban art

description: While contemporary historians have explored the advent of graffiti as well as its link to the social and financial world, little attention has been given to overarching lenses that attempt to encompass the new global contemporary form of graffiti. In a recent catalogue of street art, Carlo McCormick argues that many of the fundamental motives and aesthetics of graffiti have transformed, requiring new lenses of analysis when comprehending the work. One of the main outcomes in the art-world system of the global contemporary is the dissolving of geographical distances that once divided art worlds from each other. As a result of evolving cultural paradigms, new parameters are required when analyzing contemporary art. It is here, in the global contemporary climate, that Gajin Fujita's Hood Rats shows how representations of American identity have transformed. With a composition of various cultures, Fujita's work offers a unique synergy of contemporary American identity. My study proposes a theoretical framework in which cultural exchange, and the identities expressed within that exchange, can be examined.
Effects of bison meat consumption on blood lipids and selective biomarkers related to cancer risk
Creators: name: Chen, Ying-Sheng
Publisher: name: University of Utah
Year: 2012
Subjects: Buffalo meat
Beef
Cancer

description: The consumption of animal fats has gained the reputation of being less healthy due to an association with increased inflammation and oxidative stress. However, red meat is also a nutrient-rich food, providing high-quality protein, vitamins B6 and B12, niacin, iron, and zinc, as well as some beneficial lipids such as conjugated linoleic acid, which is believed to have ti-carcinogenic properties. The aim of the study is to investigate the influence of the daily consumption of bison and beef on blood lipids and biomarkers of inflammation and oxidative stress. Twenty-four participants completed a double-blind  cross-over randomized trial. They subsisted upon their assigned diet (3-4 oz of beef or  bison meat twice a day, 6 days/week) for 6 weeks. Test participants maintained their body weights without a significant gain or loss over the 42-day period. In comparison to beef, bison meat contained higher level of n3 and n6 fatty acids, and PUFA, lower amounts of C14 and C16 fatty acids and SEA, a more favorable P/S and lower n6/n3.  Total serum C-14:() and C-16:0 were significantly increased in the beef fed group  (p<0.01), but there were no significant differences in TC, LDL, HDL, and TG levels in  both groups. Serum high sensitivity CRP levels were unchanged in both groups.  PGF2a and urine 8-OHdG were significantly reduced in the beef fed group (p<0.01).  Serum total alkenals was significantly decreased (p<0.01) in the bison group but slightly  increased in the beef group. Overall, participants consuming bison meat had a more  favorable serum fatty acid composition. The fatty acid profile along with the lower  amount of fat contained in the bison meat is consistent with a decreased risk of cancer.  I lowever, there was no significant difference in oxidative stress biomarkers between the  two groups. Based upon the limited oxidative stress biomarkers studied, bison meat was  not consistently associated with reducing the risk of oxidative stress that has been linked  to cancer risk, compared to beef. Therefore, the results of this study suggest that  moderate amounts of red meat can be consumed as part of the eucaloric daily diet without  negatively influencing the lipid profile and inflammation and cancer risk biomarkers.  v
Apoptotic effect of jaceosidin on MCF-7 human breast cancer cells through modulation of ERK and p38 MAPK pathways
Creators: name: Ojulari, Oyindamola Vivian
name: Chae, Jong-Beom
name: Lee, Seul Gi
name: Min, Kyoungjin
name: Kwon, Taeg Kyu
name: Nam, Ju-Ock
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer

description: Jaceosidin a flavone abundant in Artemisia species has been used for its beneficial effects. This study investigated the apoptotic effect of jaceosidin treatment on MCF-7 human breast cancer cells at varying concentrations of (0, 10, 20 and 40 µM) for 24 and 48 h treatment times. Jaceosidin treatment induced a significant (p < 0.05) dose-dependent increase in apoptosis of MCF-7 cells. Jaceosidin similarly modulated the expressions of apoptosis-associated proteins, and revealing a coaction between Bax and Bcl-2, striking a balance between cell survival/cell deaths. Besides, a significant increase in pro-apoptotic expression of cleaved PARP which is a key executioner in apoptosis was observed. Apoptosis was confirmed in the cells by flow cytometry which indicated an early apoptosis (7%, 17%), as well as late apoptosis (36%, 40%) of the cells in varying percentages as treatment concentration increased. Thus, this study demonstrates that jaceosidin could be used as a potential treatment for breast cancer.
Improved prediction of need for therapeutic laparotomy using existing data
Creators: name: Nielson, Jeffrey A.
Publisher: name: University of Utah
Year: 2012
Subjects: Ultrasonics in medicine
Abdomen - Blunt trauma
Abdomen - Surgery

description: Organ injury in blunt trauma requires rapid diagnosis to obtain the best outcome, and the optimal means of diagnosis continues to be refined. The focused abdominal sonography in trauma (FAST) examination was initially developed to help rapidly identify those blunt trauma patients who require emergent laparotomy. Since first validated in these patients, the clinical use of the FAST exam has expanded to include all trauma patients generally. When applied to hemodynamically stable blunt trauma patients, the FAST exam is less sensitive for detecting internal injury, and particularly for detecting the need for laparotomy. Combining FAST results with a measure of hemodynamic stability might better predict the need for emergent laparotomy as a therapeutic intervention and thus give a more meaningful predictive value to the positive test. In this study, determination was made as to whether a first measured shock index of > 1, when combined with a positive FAST examination, better predicts the need for therapeutic laparotomy in blunt trauma patients than FAST alone. If validated, such a rule might be used as a decision support element of a computerized clinical point-of-care documentation tool for the traumatically injured.  We performed a retrospective, case-control study to evaluate the predictive value of shock index and FAST exam on blunt trauma patients. Data were obtained from an American College of Surgeons-verified Level One trauma center during the year 2003. Patients were included in the study if they were injured by blunt mechanism and if they required the highest level of trauma team activation by standardized institutional criteria. Patients were excluded if they had prior diagnostic peritoneal lavage (DPL) or transfusion, or were less than 14 years of age. The lowest of first emergency department and pre-hospital-recorded values for heart rate and systolic blood pressure were used to calculate the shock index.  Four hundred ninety-one patients were included in the study, 27 of whom underwent emergent laparotomy (rate 5.50%). Two of these laparotomies were classified as nontherapeutic."" 344 patients had FAST results recorded for analysis. The sensitivity of a positive FAST exam plus shock index > 1 for therapeutic laparotomy was 44.0% (95% CI 26.3-62.8%), specificity 99.4% (95% CI 98.0-99,9%). Comparing the predictive values of the two tests yielded: +FAST, SI > 1 = 74%; +FAST, SI< 1 = 24%, -FAST, SI > 1 = 15%, -FAST, SI< 1 = 1% (each at p < 0.01). Results of both predictive tests were obtained using computerized data.""
Brief an [Johann III Bernoulli]
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1781

description: von N[iklaus] Fuss
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Brief an J[ohann] III Bernoulli
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1780

description: von Niklaus Fuss
description: Mit Oblate
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Brief an [Johann III Bernoulli]
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1781

description: von Niklaus Fuss
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Druck: Astron. Jahrb. Berlin f. 1784, 180-1
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Jatropha mutabilis, a new source of vitexin: HPLC quantification and pharmacological evaluation
Creators: name: Costa, Eliatania Clementino
name: Menezes, Pedro Modesto Nascimento
name: Silva, Fabrício Souza
name: de Araújo Ribeiro, Luciano Augusto
name: Rolim, Larissa Araújo
name: da Cruz Araújo, Edigênia Cavalcante
name: Nunes, Xirley Pereira
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology

description: Jatropha mutabilis (Pohl) Baill is an endemic species of the Caatinga biome, little studied in terms of chemical composition. The objective of this work was to develop an analytical methodology to quantify vitexin in the ethanolic extract of J. mutabilis and to evaluate the expectorant and antitussive activities in mice. The expectorant activity was performed by measuring the phenol red obtained from the bronchoalveolar fluid in animals and the antitussive activity was evaluated by the cough method induced by citric acid (0.4 M). The method developed by HPLC–DAD proved to be simple, linear, precise, accurate, robust and specific. Besides, both vitexin (0.2, 1 and 5 mg/kg) and the extract of J. mutabilis (20, 102, 510 mg/kg) showed efficacy in decrease cough and increase aqueous mucus in mice, but vitexin was more potent. Lastly, the identification of vitexin opens the possibility of new studies for J. mutabilis.
Brief an [Bernard le Bovier de] Fontenelle
Creators: name: Bernoulli, Johann
Publisher: name: [s.n.]
Year: 1729

description: von Johann I Bernoulli
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
description: Weitere Abschrift unter L Ia 908:Bl.24
Brief an [Johann III Bernoulli]
Creators: name: Fries, Johann
Publisher: name: [s.n.]
Year: 1781

description: von [Johann] von Fries
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Brief an [Johann III Bernoulli]
Creators: name: Fries, Johann
Publisher: name: [s.n.]
Year: 1781

description: von [Johann von Fries]
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Brief an [Bernard le Bovier de] Fontenelle
Creators: name: Bernoulli, Johann
Publisher: name: [s.n.]
Year: 1729

description: von Johann I Bernoulli
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
description: Weitere Abschrift unter L Ia 908:Bl.25-27
Brief an [Bernard le Bovier de] Fontenelle
Creators: name: Bernoulli, Johann
Publisher: name: [s.n.]
Year: 1728

description: von Johann I Bernoulli
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
description: Weitere Abschrift unter L Ia 908:Bl.22-23r oben
Automated system for measuring tip impedance and among-electrode shunting in high-density microelectrode arrays
Creators: name: Gunalan, Kabilar
Publisher: name: University of Utah
Year: 2012
Subjects: Electrode characteristics
Impedance testing
Microelectrode array
Shunting impedance

description: Microelectrode arrays are being routinely used today as  a means to better understand and interface with the nervous system, in order to develop prostheses that can  restore function in systems that do not function properly.  The development and effective use of robust high-­?channel-­?count microelectrode arrays for neuronal recording and stimulation depends on effective monitoring of electrode impedances and how these change over time. For multielectrode arrays, conventional  electrode impedance measurements may be confounded  by possible shunting of signals among electrodes. Additionally, most present methods to monitor impedances in high-­?electrode-­?count arrays are laborintensive, requiring manual testing of one individual  electrode at a time. The research effort described herein  included the development of a system capable of automatically measuring the impedances of each microelectrode on a 100-­?microelectrode array with a  1-­?kHz, 10-­?mV sine wave.
Additional file 1 of Vitamin C attenuates predisposition to high-fat diet-induced metabolic dysregulation in GLUT10-deficient mouse model
Creators: name: Jiang, Chung-Lin
name: Tsao, Chang-Yu
name: Lee, Yi-Ching
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Figure S1. Mice from different genotypes or treatment groups exhibit no significant differences in food intake, water intake, physical activity, or energy expenditure. Figure S2. AA supplementation has no obvious effect on histology of sWAT of HFD-fed GLUT10G128E and WT mice.
Brief an [Johann III Bernoulli]
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1786

description: von N[iklaus] Fuss
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Information transfer and transformation in the primate ventral auditory processing stream
Creators: name: Smith, Elliot Hansen
Publisher: name: University of Utah
Year: 2013
Subjects: Auditory
Brain
Cortex
Electrophysiology
Human
Information

description: The primate auditory system is responsible for analyzing complex patterns of pressure differences and then synthesizing this information into a behaviorally relevant representation of the external world. How the auditory cortex accomplishes this complex task is unknown. This thesis examines the neural mechanisms underlying auditory perception in the primate auditory cortex, focusing on the neural representation of communication sounds. This thesis is composed of three studies of auditory cortical processing in the macaque and human. The first examines coding in primary and tertiary auditory cortex as it relates to the possibility for developing a stimulating auditory neural prosthesis. The second study applies an information theoretic approach to understanding information transfer between primary and tertiary auditory cortex. The final study examines visual influences on human tertiary auditory cortical processing during illusory audiovisual speech perception. Together, these studies provide insight into the cortical physiology underlying sound perception and insight into the creation of a stimulating cortical neural prosthesis for the deaf.
The impact that β-citronellol isomers have on the biofilm formation of Candida yeasts
Creators: name: de Figueredo Silva, Daniele
name: Cordeiro, Laísa Vilar
name: Figueiredo, Pedro Thiago Ramalho
name: Diniz-Neto, Hermes
name: da Silva Souza, Helivaldo Diógenes
name: de Oliveira Lima, Edeltrudes
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Infections associated with biofilms developed by Candida spp. are becoming a great problem due to its resistance against the immune response of the host and the action of antifungal agents. Hence, finding substances that can inhibit the development of biofilms increases the likelihood that these compounds one day can become good antifungals applied in the clinic. The aim of this study was to evaluate the effect of β-citronellol enantiomers on the biofilm formation by Candida albicans and Candida tropicalis isolated from bloodstream infections. Inhibition was evaluated by reading microplates treated with different concentrations of R-(+)-β-citronellol, S-(–)-β-citronellol and amphotericin B, compared to negative control, in spectrophotometer at 590 nm. All tested concentrations of β-citronellol enantiomers inhibited the biofilm formation of Candida. However, it is still necessary to evaluate the behavior of these isomers on mature biofilms, so that they can become more viable as antifungal therapeutical agents.
Traditional conceptions of health and nursing in Korea
Creators: name: Lee, Young-ja
Publisher: name: University of Utah
Year: 2012
Subjects: Korea

description: The purpose of this study was to identify traditional concepts of health and nursing in Korea. These concepts have their place in the traditional Korean world view. The T'ai-Chi-Tu Shuo and other classical works define three principles of the traditional Eastern-Asian world view. They are change, unity, and humanity. In order to locate the concepts of health and nursing, each of these three principles was divided into subprinciples: (a) change into production, cycle, mean, and synchronicity; (b) unity into organic system, immanency, holism, and harmony; and (c) humanity into reverence, loyalty, empathy, and filial piety. A study of the classical works revealed three components of the concept of health: (a) conformity with natural law, (b) temperance, and (c) self-regulation. These three elements were correlated with the 12 subprinciples of cosmology mentioned above. This correlation led to the definition of health as 'the process pursuing harmonious relations with the environment through self-regulation based on the principles of mean.' From the classical works, the following aspects of nursing care were evident: environment, diet, exercise, bedside care, medication, fetal discipline, and infant care. In their treatment, it became clear that nursing is closely related to the humanistic principles of loyalty, empathy, and filial piety, in addition to those of mean and harmony. This correlation led to the definition of nursing as 'caring for others with loyalty and empathy to promote their health and their recovery from illness.' The traditional Korean concept of health is a naturalistic view that emphasizes harmony with nature, while the concept of nursing calls for tending others with wholehearted devotion and empathy. This background study provides an understanding of traditional Korean concepts of health and nursing in order to facilitate nursing reforms in Korea.
Scybalocanthon nigriceps
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Scybalocanthon
Scybalocanthon nigriceps

description: § Scybalocanthon nigriceps (Harold, 1868)
Canthon nigriceps Harold 1868a: 49 (French Guiana, Brazil) Distribution. French Guiana: Harold 1868a: 49 (as Canthon nigriceps); Balthasar 1939e: 193 (as Canthon nigriceps); Blackwelder 1944: 200 (as Canthon nigriceps); Pereira and Martínez 1956b: 119; Vulcano and Pereira 1964: 638. Brazil: Harold 1868a: 49 (as Canthon nigriceps); Gillet 1911b: 31 (as Canthon nigriceps); Balthasar 1939e: 193 (as Canthon nigriceps); Blackwelder 1944: 200 (as Canthon nigriceps); Pereira and Martínez 1956b: 119; Vulcano and Pereira 1964: 638; Vaz-de-Mello 2000: 195; Ferreira et al. 2017: 1636; Silva and Valois 2019: 329. Other: Ferreira et al. 2017: 1636 (Bolivia, Paraguay); Silva and Valois 2019: 329 (Argentina, Paraguay).
Note. To our knowledge there are no recent records of Scybalocanthon nigriceps for the research area. The records for French Guiana in Balthasar (1939e: 193), Blackwelder (1944: 200), Pereira and Martínez (1956b: 119) and Vulcano and Pereira (1964: 638) appear to have been taken from Harold (1868a: 49), with the latter possibly being based on a mislabeled specimen. According to Silva and Valois (2019: 329), this species is restricted to an area in southern Brazil, southern Paraguay and northern Argentina. This species is absent from the research area.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on pages 81-82, DOI: 10.5281/zenodo.3678492
Brief an [Johann III Bernoulli]
Creators: name: Frisi, Paolo
Publisher: name: [s.n.]
Year: 1776

description: von [Paolo] Frisi
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Druck: B. Nouv. litt. (Suppl. recl. astr.), 1, 1776, 18
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Integrating mind and body healing into primary care: a team approach
Creators: name: Reiss-Brennan, Brenda
Publisher: name: University of Utah
Year: 2013
Subjects: Chronic conditions
Depression
Mind-body healing
Patient reported outcome
Primary care
Team care

description: This publication examines the impact of integrating mental health into primary health care. Mental Health Integration (MHI) in Intermountain Healthcare (IH) has changed the culture of primary health care by standardizing a team-based care process that includes mental health as a normal part of the routine medical encounter. MHI sees mental illness through a new lens integrating mind and body and introduces a team approach that values both the patient and staff experiences. This multisite comparative study using qualitative techniques reports on health outcomes associated with MHI for patients and staff. Fifty-nine patients and 50 staff were interviewed to evaluate the impact of MHI on care for depression. Patients receiving MHI reported an improved relationship with caregivers (p
Brief an J[ohann] III Bernoulli
Creators: name: Fuss, Nikolaj I.
Publisher: name: [s.n.]
Year: 1785

description: von Niklaus Fuss
description: Mit Spuren von einem roten Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2014 Vollständige Rekatalogisierung nach Standortverzeichnis
Biosynthesis of pancreatic ribonuclease
Creators: name: Morris, Allan J.
Publisher: name: University of Utah
Year: 2012
Subjects: Biosynthesis
Orcinol
Analysis

description: Methods have been developed for the study of amino acid incorporation into a specific protein under established conditions of net synthesis. The results of these studies have been reported and discussed.  Synthesis and storage of the secretory proteins of mouse pancreas have been shown to occur between fifteen to twenty-one hours after pilocarpine injections. The concentration of amylase, ribonuclease, and total pancreatic proteins has been shown to increase rapidly during that period. Deoxyribonucleic acid as well as ribonucleic acid content of the pancreatic tissue does not increase during the period of protein synthesis.  Injection of the labeled amino acid, valine, into pilocarpine treated mice eighteen hours after stimulation, followed by chromatographic resolution of the components of an extract of pancreas, has allowed a demonstration of radioactive labeling of the enzyme ribonuclease under conditions of net synthesis. The ratio of radioactivity to enzymatic activity has been used to define a specific activity for that enzyme.  Analyses of the total radioactivity present in the pancreatic tissue as well as the total radioactivity of each of four cell fractions have been carried out. It was found that ten minutes after intraperitoneal injection of isotope approximately ten per cent of the radioactivity is present in the pancreas. Radioactivity appears most rapidly in the microsomal fraction of the cell during the first ten minutes but at later periods the soluble portion of the cell becomes more intensely labeled. The distribution of labeled ribonuclease in the various parts of the pancreatic cells has been studied as a function of time. The data indicate that the microsomal portion of the acinar cells is the site of formation of the secretory enzyme, ribonuclease, in the living mouse.  The distribution of labeled ribonuclease in the other cell fractions suggests that the newly formed enzyme is transferred to the zymogen granules by way of the soluble portion of the cell.  From a consideration of the rates of isotope uptake into the total homogenate and the microsomal fraction, as well as the rate of appearance of labeled ribonuclease in the microsomal fraction, it has been estimated that the labeled amino acid is present in the microsomes for about three minutes before it appears in the pancreatic enzyme.    It has been proposed that this time lag is the period required for the elaboration of the finished, enzymatically active protein, ribonuclease, in the microsomal portion of the cells.