cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Establishing Outcome Parameters for Helicopter Emergency Medical Services Research in the Netherlands: Results of a Mixed-Methods Delphi Consensus Study
Creators: name: Vianen, Niek J.
name: Campfens, J. Reinout
name: Brouwer-Bergsma, Margot
name: Van Ditshuizen, Jan C.
name: Giannakopoulos, Georgios F.
name: Hoogerwerf, Nico
name: Hartog, Dennis den
name: Van Lieshout, Esther M.M.
name: Maissan, Iscander M.
name: Schober, Patrick
name: Venema, Lieneke
name: Verhofstad, Michael H.J.
name: Van Vledder, Mark G.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Physician staffed Helicopter Emergency Medical Services (P-HEMS) care in the Netherlands has transitioned from predominantly trauma management to handling a variety of medical conditions. Relevant outcome parameters for Dutch P-HEMS research have not been previously defined. National consensus was sought to identify relevant long term patient outcome parameters, process outcome parameters and performance outcome parameters for Dutch P-HEMS care. This was a mixed methods Delphi consensus study. A list of potentially relevant outcome parameters was identified using a systematic literature review. These parameters were subsequently surveyed in a Delphi consensus study. Helicopter Emergency Medical Services physicians and relevant stakeholders were invited to participate in this Delphi survey, where they were allowed to suggest additional outcome parameters. Descriptive analysis was performed on all data sets. Forty-nine potential outcome parameters for Dutch P-HEMS care were surveyed. Of 71 invited participants, 53 (75%), 40 (56%), and 20 (28%) participated in the first, second, and third round of the Delphi study, respectively. Consensus was reached on 25 (51%) of 49 outcome parameters as being important. These consisted of seven long term patient related outcome parameters, four short term patient related outcome parameters, five process outcome parameters and nine performance outcome parameters. In conclusion, this study identified 25 outcome parameters relevant for Dutch physician staffed HEMS care. These parameters should be considered when designing future studies and should be routinely collected for each dispatch if possible.
Additional file 1 of Infrared: a declarative tree decomposition-powered framework for bioinformatics
Creators: name: Yao, Hua-Ting
name: Marchand, Bertrand
name: Berkemer, Sarah J.
name: Ponty, Yann
name: Will, Sebastian
Publisher: name: figshare
Year: 2024
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences
subject: Computation Theory and Mathematics

description: Additional file 1. Correctness proofs. The file contains proofs of Propositions 1, 2 and 3, which establish the correctness of the optimization and sampling algorithms.
Adverse event profile of ocular injury associated with JAK inhibitors in patients with rheumatoid arthritis: a disproportionality analysis
Creators: name: Li, Dan
name: Yang, Xiongwen
name: Li, Yueyan
name: Kuang, Hongying
name: Tong, Qin
name: Yang, Bo
name: Chen, Danjun
name: Fu, Chengxiao
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine

description: Janus kinase inhibitors (JAKIs) have been approved for the treatment of rheumatoid arthritis (RA) for several years. A recent real-world study has shown the possibility of a relationship between the occurrence of ocular adverse events (OEs) and the use of JAKIs but failed to rule out whether those OEs are related to RA. A retrospective, pharmacovigilance study using the FDA Adverse Event Reporting System to evaluate OE reports following treatment with JAK inhibitors in patients with RA from Q1 2004 to Q1 2024. We identified 3226 cases associated with JAKIs and 24,158 cases associated with TNFIs. Most of the OEs are serious cases, the age distribution was similar but the sex distribution was not balanced. The OEs with top 10 ROR values in TNFIs had no detectable signal in JAKIs, and the time of onset of OEs also shows difference. Besides, far fewer OE were reported for baricitinib than for the other JAKIs. Different types of JAKIs are associated with special types of OEs and differ in time of onset compared with TNF inhibitors. More rigorous trials should be conducted to better understand the risk factors in JAKIs-related OEs.
Supplemental Material, sj-docx-1-jsr-10.1177_10946705211027659 - Frontline Employee Passion: A Multistudy Conceptualization and Scale Development
Creators: name: C. Crawford, Angela
name: Newmeyer, Casey E.
name: Jung, Jin Ho
name: Arnold, Todd J.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 150402 Hospitality Management

description: Supplemental Material, sj-docx-1-jsr-10.1177_10946705211027659 for Frontline Employee Passion: A Multistudy Conceptualization and Scale Development by Angela C. Crawford, Casey E. Newmeyer, Jin Ho Jung and Todd J. Arnold in Journal of Service Research
Incidence and risk of drug-induced interstitial lung disease associated with anti-neoplastic drugs
Creators: name: Hwang, Il-Hyung
name: Lee, Seung Hyeun
name: Lee, Hankil
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: To evaluate the incidence and risk of drug-induced interstitial lung disease (DIILD) associated with anti-neoplastic drugs among patients with cancer in Korea. This nested case-control study included 457,685 patients diagnosed with cancer and treated with anti-neoplastic drugs from a retrospective nationwide population-based cohort between 2017 and 2021. The incidence rate of DIILD and the risks of DIILD by anti-neoplastic drug categories were analyzed. Among 270,595 patients, 2,634 developed ILD, resulting in an incidence rate of 4.12 per 1,000 person-years (95% confidence interval (CI): 3.97–4.28). DIILD was more prevalent in men, older patients, and those with a history of pulmonary disease or lung cancer. In a multivariable conditional logistic regression analysis, immune checkpoint inhibitors (odds ratio (OR): 2.37; 95%CI: 1.48–3.78), mammalian target of rapamycin inhibitors (OR: 9.79; 95%CI: 5.20–18.45), antibody-drug conjugates (OR: 7.99; 95%CI: 3.24–19.74), cyclin-dependent kinase 4/6 inhibitors (OR: 2.28; 95%CI: 1.26–4.12), and any combination of different drug categories (OR: 1.93; 95%CI: 1.21–3.09) were associated with an increased risk of DIILD. Our findings suggest that the risk of incident DIILD depends on the category of anti-neoplastic drugs. Patients with identified risk factors and treated with these drugs should be monitored closely.
Evaluating the Application of an EMS Clinical Judgment Theoretical Framework
Creators: name: McAllister, Nicole T.
name: McBride, Nadine L.
name: Salhi, Hussam E.
name: Fauvel, Alix Delamare
name: Keating, Glen
name: Smiley, Abbey
name: Gage, Christopher B.
name: Powell, Jonathan R.
name: Panchal, Ashish R.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Neuroscience
subject: Biotechnology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Clinical judgment (CJ) encompasses clinical reasoning (process of evaluating a problem) and clinical decision-making (choice made). A theoretical model to better define emergency medical services (EMS) CJ has been developed but its use has not been evaluated in EMS training and assessments. Our objective was to evaluate the performance of this EMS CJ model to assess clinical reasoning and decision-making in a simulated environment. In this evaluation, EMS clinician teams (2–3 members) were directed to care for a simulated older adult patient in their home following a fall. Simulations were video recorded, clinician team actions coded, and evaluated for whether proper CJ reasoning and decisions were made. We evaluated CJ in two ways: 1) EMS medical directors’ (MD) determination of whether the CJ questions were addressed (MD score) and 2) objective rubric evaluation of CJ questions using the EMS CJ model focused on recognition of appropriate cues, performance of actions, and revaluation after action (rubric score). The CJ questions addressed in this simulation included: 1) Is the patient stable/unstable?, 2) Are interventions necessary before movement?, 3) How should the patient be transferred from the floor?, and 4) Does the cause of the fall require hospital evaluation? Descriptive statistics were calculated, and concordance between the two assessments was evaluated (mean, 95% CI). Percent concordance was calculated with a validity threshold set at 70%. Four EMS MDs reviewed 20 videos addressing 80 clinical judgment decisions. Overall concordance between MD score and rubric score for CJ decisions was above the threshold at 88.1% (85.0, 91.2). Concordance between MD score and rubric score for each CJ decision was 92.0% (87.3, 96.7) for question 1, 79.9% (71.5, 88.3) for question 2, 95.0% (90.4, 99.6) for question 3, and 85.4% (79.5, 91.2) for question 4. An objective evaluation of CJ decisions using a rubric derived from an EMS CJ theoretical framework demonstrated high concordance to subjective evaluations of CJ made by EMS MDs. This approach may allow for reproducible and objective CJ evaluations that could be used for competency assessment in EMS.
Determinants of tick-borne encephalitis in counties of southern Germany, 2001-2008
Creators: name: Kiffner, Christian
name: Zucchini, Walter
name: Schomaker, Philipp
name: Vor, Torsten
name: Hagedorn, Peter
name: Niedrig, Matthias
name: Rühe, Ferdinand
Publisher: name: Robert Koch-Institut
Year: 2010
Subjects: subject: Adolescent
subject: Newborn
subject: Humans
subject: Female
subject: Germany/epidemiology
subject: Male
subject: Middle Aged
subject: Population Surveillance/methods
subject: Animals
subject: Models
subject: Child
subject: Adult
subject: Aged
subject: Infant
subject: Logistic Models
subject: Encephalitis
subject: Tick-Borne/epidemiology
subject: Young Adult
subject: Child Preschool
subject: Encephalitis Viruses
subject: Tick-Borne/immunology
subject: Tick-Borne/etiology
subject: Geography
subject: Theoretical
subject: Temperature
subject: 610 Medizin

description: Background: Tick-borne encephalitis (TBE) virus can cause severe symptoms in humans. The incidence of this vector-borne pathogen in humans is characterised by spatial and temporal heterogeneity. To explain the variation in reported human TBE cases per county in southern Germany, we designed a time-lagged, spatially-explicit model that incorporates ecological, environmental, and climatic factors. Results: We fitted a logistic regression model to the annual counts of reported human TBE cases in each of 140 counties over an eight year period. The model controlled for spatial autocorrelation and unexplained temporal variation. The occurrence of human TBE was found to be positively correlated with the proportions of broad-leafed, mixed and coniferous forest cover. An index of forest fragmentation was negatively correlated with TBE incidence, suggesting that infection risk is higher in fragmented landscapes. The results contradict previous evidence regarding the relevance of a specific spring-time temperature regime for TBE epidemiology. Hunting bag data of roe deer (Capreolus capreolus) in the previous year was positively correlated with human TBE incidence, and hunting bag density of red fox (Vulpes vulpes) and red deer (Cervus elaphus) in the previous year were negatively correlated with human TBE incidence. Conclusions: Our approach suggests that a combination of landscape and climatic variables as well as hostspecies dynamics influence TBE infection risk in humans. The model was unable to explain some of the temporal variation, specifically the high counts in 2005 and 2006. Factors such as the exposure of humans to infected ticks and forest rodent population dynamics, for which we have no data, are likely to be explanatory factors. Such information is required to identify the determinants of TBE more reliably. Having records of TBE infection sites at a finer scale would also be necessary.
sj-docx-1-aim-10.1177_09645284211027892 – Supplemental material for Regulation of serum microRNA expression by acupuncture in patients with diarrhea-predominant irritable bowel syndrome
Creators: name: Guo, Jing
name: Lu, Gao
name: Chen, Lu
name: Geng, Hao
name: Wu, Xiaoliang
name: Chen, Hao
name: Li, Yang
name: Yuan, Mengqian
name: Sun, Jianhua
name: Pei, Lixia
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental material, sj-docx-1-aim-10.1177_09645284211027892 for Regulation of serum microRNA expression by acupuncture in patients with diarrhea-predominant irritable bowel syndrome by Jing Guo, Gao Lu, Lu Chen, Hao Geng, Xiaoliang Wu, Hao Chen, Yang Li, Mengqian Yuan, Jianhua Sun and Lixia Pei in Acupuncture in Medicine
Additional file 1 of AraDQ: an automated digital phenotyping software for quantifying disease symptoms of flood-inoculated Arabidopsis seedlings
Creators: name: Lee, Jae Hoon
name: Lee, Unseok
name: Yoo, Ji Hye
name: Lee, Taek Sung
name: Jung, Je Hyeong
name: Kim, Hyoung Seok
Publisher: name: figshare
Year: 2024
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1. Primers used in this study. Primer sequences used for mutagenesis and confirmation of mutagenesis are listed in the table.
PpiD is a player in the network of periplasmic chaperones in Escherichia coli
Creators: name: Matern, Yvonne
name: Barion, Birgitta
name: Behrens-Kneip, Susanne
Publisher: name: Robert Koch-Institut
Year: 2010
Subjects: subject: Escherichia coli/genetics
subject: Escherichia coli/metabolism
subject: Escherichia coli Proteins/genetics
subject: Bacterial Outer Membrane Proteins/metabolism
subject: Bacterial Outer Membrane Proteins/genetics
subject: Carrier Proteins/genetics
subject: Carrier Proteins/physiology
subject: Escherichia coli Proteins/physiology
subject: Molecular Chaperones/genetics
subject: Molecular Chaperones/physiology
subject: Peptidylprolyl Isomerase/genetics
subject: Peptidylprolyl Isomerase/physiology
subject: Periplasm/metabolism
subject: Protein Folding
subject: 610 Medizin

description: Background: The inner membrane-anchored periplasmic folding factor PpiD is described as a parvulin-like peptidyl prolyl isomerase (PPIase) that assists in the maturation of the major beta-barrel outer membrane proteins (OMPs) of Escherichia coli. More recent work however, calls these findings into question. Here, we re-examined the role of PpiD in the E. coli periplasm by analyzing its functional interplay with other folding factors that influence OMP maturation as well as general protein folding in the periplasmic compartment of the cell, such as SurA, Skp, and DegP. Results: The analysis of the effects of both deletion and overexpression of ppiD on cell envelope phenotypes revealed that PpiD in contrast to prior observations plays only a minor role, if any, in the maturation of OMPs and cannot compensate for the lack of SurA in the periplasm. On the other hand, our results show that overproduction of PpiD rescues a surA skp double mutant from lethality. In the presence of increased PpiD levels surA skp cells show reduced activities of both the SigmaE-dependent and the Cpx envelope stress responses, and contain increased amounts of folded species of the major OMP OmpA. These effects require the anchoring of PpiD in the inner membrane but are independent of its parvulin-like PPIase domain. Moreover, a PpiD protein lacking the PPIase domain also complements the growth defects of an fkpA ppiD surA triple PPIase mutant and exhibits chaperone activity in vitro. In addition, PpiD appears to collaborate with DegP, as deletion of ppiD confers a temperature-dependent conditional synthetic phenotype in a degP mutant. Conclusions: This study provides first direct evidence that PpiD functions as a chaperone and contributes to the network of periplasmic chaperone activities without being specifically involved in OMP maturation. Consistent with previous work, our data support a model in which the chaperone function of PpiD is used to aid in the early periplasmic folding of many newly translocated proteins.
Critical Velocity of High-Performance Yarn Transversely Impacted by Different Indenters
Creators: name: Lim, Boon Him
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Aerospace materials

description: Critical velocity is defined as projectile striking velocity that causes instantaneous rupture of the specimen under transverse impact. The main goal of this dissertation was to determine the critical velocities of a Twaron® 2040 warp yarn impacted by different round indenters. Special attention was placed to develop models to predict the critical velocities when transversely impacted by the indenters. An MTS 810 load frame was utilized to perform quasi-static transverse and uniaxial tension experiments to examine the stress concentration and the constitutive mechanical properties of the yarn which were used as an input to the models. A gas/powder gun was utilized to perform ballistic experiments to evaluate the critical velocities of a Twaron® 2040 warp yarn impacted by four different type of round projectiles. These projectiles possessed a radius of curvature of 2 μm, 20 μm, 200 μm and 2 mm. The results showed that as the projectile radius of curvature increased, the critical velocity also increased. However, these experimental critical velocities showed a demonstrated reduction as compared to the classical theory. Post-mortem analysis via scanning electron microscopy on the recovered specimens revealed that the fibers failure surfaces changed from shear to fibrillation as the radius of curvature of the projectile increased. To improve the prediction capability, two additional models, Euler-Bernoulli beam and Hertzian contact, were developed to predict the critical velocity. For the Euler–Bernoulli beam model, the critical velocity was obtained by assuming the specimen ruptured instantaneously when the maximum flexural strain reached the ultimate tensile strain of the yarn upon impact. On the other hand, for the Hertzian contact model, the yarn was assumed to fail when the indentation depth was equivalent to the diameter of the yarn. Unlike Smith theory, the Euler-Bernoulli beam model underestimated the critical velocity for all cases. The Hertzian model was capable of predicting the critical velocities of a Twaron® 2040 yarn transversely impacted by 2 μm and 20 μm round projectiles.
Oxidative pressurized acid leaching of waste printed circuit boards
Creators: name: Lundstrom, Mari
name: Seisko, Sipi
name: Jascisak, Jan
name: Orac, Dusan
name: Aromaa, Jari
name: Havlik, Tomas
name: Forsen, Olof
Publisher: name: Faculty of Geoengineering, Mining and Geology, Wrocław University of Technology, Wrocław
Year: 2017
Subjects: batch leaching
sulfuric acid
copper
tin
gas formation

description: Physicochemical Problems of Mineral Processing; ISSN 2084-4735
The #OthelloSyllabus: Twitter as Play
Creators: name: Ballou, Sienna
name: Tavares, Elizabeth
Publisher: name: Humanities Commons
Year: 2020
Subjects: subject: Shakespeare, William, 1564-1616
subject: English drama
subject: Sixteenth century
subject: Seventeenth century
subject: Social media
subject: Teaching

description: Two guerrilla movements have disrupted Digital Humanities pedagogy in the past decade: the event syllabus, and the appropriation of Twitter as a composition genre. The event syllabus typically presents as a web-based archive of articles that help the public both instruct themselves about racialized violence and provides resources to teach a kind of cultural competency in the classroom from a specific case. Typically these begin with a call for public education through Twitter with hashtags such as #FergusonSyllabus, #OrlandoSyllabus or #PulseSyllabus, and #CharlestonSyllabus, the latter of which is now an edited collection from the University of Georgia Press. In our course, “#OthelloSyllabus: Cyprus, Ferguson, Forest Grove,” freshmen employed the rhetoric of hashtag activism to engage with critical race theory across a spectrum of texts, including a documentary on the Black Lives Matter (BLM) movement, William Shakespeare’s Othello, and Jordan Peele’s Get Out. In weekly twessays, posting responses during community lectures, and in devising a Twitter play, the platform’s paradoxical mix of anonymity and very public writing worked to develop in students a cultural competency.
Prevalence and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) among pigs on German farms and import of livestock-related MRSA into hospitals
Creators: name: Köck, Robin
name: Harlizius, J.
name: Bressan, N.
name: Laerberg, R.
name: Wieler, Lothar H.
name: Witte, Wolfgang
name: Deurenberg, R. H.
name: Voss, A.
name: Becker, Karsten
name: Friedrich, Alexander W.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2009
Subjects: subject: Adolescent
subject: Preschool
subject: Bacterial/genetics
subject: DNA
subject: Humans
subject: Female
subject: Genotype
subject: Germany/epidemiology
subject: Hospitals
subject: Male
subject: Middle Aged
subject: Prevalence
subject: Risk Factors
subject: Animals
subject: Child
subject: Adult
subject: Aged
subject: Infant
subject: Swine
subject: Swine Diseases/epidemiology
subject: Cross Infection/microbiology
subject: Zoonoses/epidemiology
subject: Young Adult
subject: Cross Infection/epidemiology
subject: Bacterial Typing Techniques
subject: Molecular Epidemiology
subject: DNA Fingerprinting
subject: Methicillin-Resistant Staphylococcus aureus/classification
subject: Methicillin-Resistant Staphylococcus aureus/isolation & purification
subject: Staphylococcal Infections/epidemiology
subject: Staphylococcal Infections/microbiology
subject: Methicillin-Resistant Staphylococcus aureus/genetics
subject: Aged 80 and over
subject: Carrier State/microbiology
subject: Carrier State/veterinary
subject: Nasal Cavity/microbiology
subject: Staphylococcal Infections/veterinary
subject: Swine Diseases/microbiology
subject: Zoonoses/microbiology
subject: Zoonoses/transmission*
subject: 610 Medizin

description: The aim of this study was to evaluate the prevalence and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) among pigs and estimate the impact of this animal reservoir on human healthcare. Nasal swabs were derived from 1,600 pigs at 40 German farms. The MRSA were characterized using S. aureus protein A (spa) typing, multilocus sequence typing (MLST) and detection of toxin genes. In a retrospective case control study, we compared risk factors for the carriage of MRSA between patients carrying spa types found among regional pigs and patients with other MRSA molecular types. Pigs carrying MRSA were identified on 70% of the farms (spa types t011, t034, t108, t1451 and t2510, all associated with MLST sequence type ST398). Contact to pigs and cattle were independent risk factors for the carriage of these spa types in patients at hospital admission. Our results indicate that livestock represents a relevant reservoir for the import of MRSA into regional German hospitals.
Increased reporting of accidental overdose with glucagon-like peptide-1 receptor agonists: a population-based study
Creators: name: McIntyre, Roger S.
name: Kwan, Angela T.H.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Computational Biology

description: The use of online and/or compounding pharmacies to access glucagon-like peptide-1 receptor agonists (GLP-1 RAs) increases the risk for prescription error (e.g. accidental overdose) especially in racial, ethnic, and socioeconomic disadvantaged groups. We sought to evaluate accidental overdose associated with GLP-1 RAs submitted to the United States FDA Adverse Event Reporting System (FAERS). Case reports of accidental overdose reported to the FAERS were retrieved from Q4 2003 to Q1 2024 using OpenVigil 2.1. Disproportionality of accidental overdose was assessed using reporting odds ratio (ROR). Upper and lower 95% confidence intervals (CI) were calculated at an alpha level of 5%, where disproportionate reporting was considered when the lower 95% CI was greater than 1.0. We identified 3,348 reports of accidental overdose associated with GLP-1 RAs. The RORs were significant for all agents within the class (ROR range: 2.64–61.12, all p < 0.008), including semaglutide, dulaglutide, exenatide, liraglutide, and tirzepatide compared to niacin. Inadequate access, availability, and affordability of GLP-1 RAs has contributed to the increased seeking via online and/or compounding pharmacies, and is associated with greater risk for prescription errors that differentially affect racial, ethnic, and socioeconomic vulnerable populations. Pharmacovigilance database analyses cannot establish causation only association.
sj-pdf-1-jet-10.1177_15266028211028213 – Supplemental material for Intraoperative Stent-Graft-Induced Aortic Intimal Intussusception During TEVAR for Type B Aortic Dissection
Creators: name: Ma, Tao
name: Liu, Fei
name: Chen, Bin
name: Jiang, Jun Hao
name: Shi, Yun
name: Guo, Da Qiao
name: Xu, Xin
name: Dong, Zhi Hui
name: Fu, Wei Guo
Publisher: name: SAGE Journals
Year: 2021
Subjects: Cardiology
Medicine
Surgery

description: Supplemental material, sj-pdf-1-jet-10.1177_15266028211028213 for Intraoperative Stent-Graft-Induced Aortic Intimal Intussusception During TEVAR for Type B Aortic Dissection by Tao Ma, Fei Liu, Bin Chen, Jun Hao Jiang, Yun Shi, Da Qiao Guo, Xin Xu, Zhi Hui Dong and Wei Guo Fu in Journal of Endovascular Therapy
She Will Be: Literary Authorship and the Coming Woman in the Postbellum United States
Creators: name: Boyle, Elizabeth
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: North American literature
Literary studies not elsewhere classified

description: She Will Be: Literary Authorship and the Coming Woman in the Postbellum United States argues that postbellum women writers deployed the figure of the Coming Woman, an archetype for the nation’s improved female future, to articulate expanded sociopolitical opportunities for women, interrogate prevailing standards of literary art, and validate their own literary pursuits. During the final decades of the nineteenth century, the American reading public became increasingly fascinated with identifying who the Coming Woman would be, what qualities she would possess, and how her arrival would alter the nation’s future. Such questions flooded US print culture in the decades between 1865 and 1900, demonstrating that the Coming Woman not only occupied a space between the antebellum True Woman and fin de siècle New Woman but also that she was a major feminine archetype in her own right.
Even so, existing scholarship on the Coming Woman tends either to identify the Coming Woman anachronistically as an early iteration of the New Woman or, when naming her directly, to overlook her complex function as both a harbinger and manifestation of manifold sociopolitical changes. These limited examinations elide the Coming Woman’s ubiquitous influence on postbellum literary culture, particularly in terms of the complex links Susan Coultrap-McQuin and Lawrence W. Levine have traced between middlebrow culture and postbellum national identity. She Will Be builds on recent scholarship by demonstrating how the American Coming Woman helped reshape notions of women’s literary authorship, modernity, and national identity in the late nineteenth century. By examining her literary life through four key middlebrow genres (Bildungsroman, sentimentality, utopianism, and regionalism), She Will Be reveals how female authors used the Coming Woman figure to imagine—and, indeed, write into being—an expanded vision for the US’s female future.
Alexandromys sachalinensis
Creators: name: Sheremetyeva, I. N.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Alexandromys
Alexandromys sachalinensis

description: 7. Alexandromys sachalinensis (Vasin 1955) — СахаΛинская поΛёвка
 Синонимы: Microtus sachalinensis Vasin, 1955: Громов и Αр. 1963; Мейер 1968; Громов, ПоΛяков 1977; Воронов и Αр. 1977; Мейер и Αр. 1996. — Microtus oeconomus sachalinensis: Бобринский и Αр. 1965. — Microtus fortis sachalinensis: Тимофеева, Сурков 1968. — Microtus maximowiczii (non Schrenk, 1858): Реймерс 1972.
 A. sachalinensis — энΑемик острова СахаΛин (Громов, Ербаева 1995; Костенко 2000; Shenbrot, Krasnov 2005; Gerrie, Kennerley 2016). На севере острова сахаΛинская поΛёвка может быть встречена вместе с ΑаΛьневосточной A. fortis. Кариотип виΑа стабиΛен (2n = 50, NFa = 60).
 СΛеΑующие три виΑа восточноазиатских поΛёвок, обитающих на территории ЗабайкаΛья и ΔВ России, на основе моΛекуΛярных, аΛΛозимных и морфоΛогических Αанных выΑеΛяют в группу бΛизкороΑственных виΑов — “ mongolicus ” (Фрисман и Αр. 2016; Bannikova et al. 2010; Pavlinov, Lissovsky 2012; Lissovsky et al. 2018): поΛёвка МиΑΑенΑорфа, монгоΛьская поΛёвка и поΛёвка Громова. Время разΑеΛения этих виΑов оценивается в 320000 Λет (Bannikova et al. 2010), что прихоΑится на начаΛо среΑнего пΛейстоцена. ПоΛёвка МиΑΑенΑорфа и монгоΛьская поΛёвка не имеют разΛичий по чисΛу и морфоΛогии хромосом (2n = 50 NFa = 56), за искΛючением трех особей монгоΛьской поΛёвки из преΑгорий Хентея в МонгоΛии, у которых обнаружено центромерное сΛияние Αвух акроцентрических в субтΛоцентрическую хромосому (2n = 49 NFa = 56). В свою очереΑь поΛёвка Громова хорошо отΛичается от Αругих виΑов этой группы, как по чисΛу, так и морфоΛогии хромосом (2n = 44 NF = 60).
description: Published as part of Sheremetyeva, I. N., 2023, Species composition and distribution of gray voles in Transbaikalia and the Russian Far East, pp. 724-743 in Amurian Zoological Journal XV (4) on page 730, DOI: 10.33910/2686-9519-2023-15-4-724-743, http://zenodo.org/record/11362261
No Evidence for XMRV in German CFS and MS Patients with Fatigue Despite the Ability of the Virus to Infect Human Blood Cells In Vitro
Creators: name: Hohn, Oliver
name: Strohschein, Kristin
name: Brandt, Alexander U.
name: Seeher, Sandra
name: Klein, Sandra
name: Kurth, Reinhard
name: Paul, Friedemann
name: Meisel, Christian
name: Scheibenbogen, Carmen
name: Bannert, Norbert
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2010
Subjects: subject: Adult
subject: Humans
subject: Female
subject: Germany
subject: Male
subject: Middle Aged
subject: Microscopy
subject: Cohort Studies
subject: Polymerase Chain Reaction/methods
subject: Enzyme-Linked Immunosorbent Assay/methods
subject: Fatigue Syndrome
subject: Cell Line Tumor
subject: Chronic/blood
subject: Fatigue Syndrome Chronic/virology
subject: Leukocytes Mononuclear/virology
subject: Fluorescence/methods
subject: Multiple Sclerosis
subject: Relapsing-Remitting/blood
subject: Relapsing-Remitting/virology
subject: Xenotropic murine leukemia virus-related virus/genetics
subject: 610 Medizin

description: Background: Xenotropic murine leukemia virus-related virus (XMRV), a novel human retrovirus originally identified in prostate cancer tissues, has recently been associated with chronic fatigue syndrome (CFS), a disabling disease of unknown etiology affecting millions of people worldwide. However, several subsequent studies failed to detect the virus in patients suffering from these illnesses or in healthy subjects. Here we report the results of efforts to detect antibody responses and viral sequences in samples from a cohort of German CFS and relapsing remitting multiple sclerosis (MS) patients with fatigue symptoms. Methodology: Blood samples were taken from a cohort of 39 patients fulfilling the Fukuda/CDC criteria (CFS), from 112 patients with an established MS diagnosis and from 40 healthy donors. Fatigue severity in MS patients was assessed using the Fatigue Severity Scale (FSS). Validated Gag- and Env-ELISA assays were used to screen sera for XMRV antibodies. PHAactivated PBMC were cultured for seven days in the presence of IL-2 and DNA isolated from these cultures as well as from co-cultures of PBMC and highly permissive LNCaP cells was analyzed by nested PCR for the presence of the XMRV gag gene. In addition, PBMC cultures were exposed to 22Rv1-derived XMRV to assess infectivity and virus production. Conclusion: None of the screened sera from CFS and MS patients or healthy blood donors tested positive for XMRV specific antibodies and all PBMC (and PBMC plus LNCaP) cultures remained negative for XMRV sequences by nested PCR. These results argue against an association between XMRV infection and CFS and MS in Germany. However, we could confirm that PBMC cultures from healthy donors and from CFS patients can be experimentally infected by XMRV, resulting in the release of low levels of transmittable virus.
Would Provision of Take Home Naloxone Kits by Emergency Medical Services be Perceived as Acceptable to People at Risk of Opioid Overdose? A Qualitative Study
Creators: name: Hughes, Jane
name: Sampson, Fiona Clare
name: Buykx, Penny
name: Long, Jaqui
name: Edwards, Adrian
name: Evans, Bridie A.
name: Goodacre, Steve
name: Jones, Matthew B.
name: Moore, Chris
name: Snooks, Helen A.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Mental Health
subject: Plant Biology

description: Take home naloxone kits can reduce mortality, but we know little about how they are perceived by people with lived experience of opioid use. Provision of naloxone in the community has been shown to significantly reduce mortality from opioid overdose. Currently, this is predominantly through drug treatment support services but expanding provision through other services might be effective in increasing kit take-up and mortality reduction. This study aimed to examine participants’ experiences of opiate overdose and acceptability of provision of naloxone kits through ambulance/paramedic emergency services (EMS) and hospital Emergency Departments (ED). Qualitative interviews were conducted with 26 people who had direct experience of opioid use. Participants were recruited at two substance-use treatment centers and a third sector support organization in three large cities in the United Kingdom. Interviews examined respondents’ experiences of opioid use and opioid overdose, access and personal use of naloxone kits, and opinions about kit provision from EMS and hospital ED staff. Interview data were thematically analyzed using a constant comparative method. Four key themes were identified during analysis: (1) High levels of overdose experience and knowledge of naloxone and naloxone kits; (2) naloxone kits were perceived as effective and easy to use; (3) There were some concerns around the risks of administering naloxone, such as peer aggression during withdrawal. (4) Participants supported much wider personal, family and peer provision of naloxone kits from community support organizations as well as from EMS. Participants felt naloxone kits were an important resource and they wanted increased provision across a range of services including EMS and hospital ED staff as well as community pharmacies and needle exchange centers. Participants wanted naloxone kit provision to be extended to peers, family and friends.
Leptospirosis in Germany, 1962–2003
Creators: name: Jansen, Andreas
name: Schöneberg, Irene
name: Frank, Christina
name: Alpers, Katharina
name: Schneider, Thomas
name: Stark, Klaus
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2005
Subjects: subject: Adolescent
subject: Preschool
subject: Humans
subject: Germany/epidemiology
subject: Middle Aged
subject: Animals
subject: Child
subject: Adult
subject: Aged
subject: Infant
subject: Seasons
subject: Occupational Exposure
subject: Leptospirosis/epidemiology
subject: Aged 80 and over
subject: Animals Domestic
subject: Disease Reservoirs
subject: History 20th Century
subject: History 21st Century
subject: Leptospirosis/history
subject: 610 Medizin

description: Epidemiologic trends of human leptospirosis in Germany were investigated by analyzing national surveillance data from 1962 to 2003 and by conducting a questionnaire-based survey from 1997 to 2000. After a steady decrease of leptospirosis incidence from 1962 to 1997, surveillance data indicate an increase in disease incidence to 0.06 per 100,000 (1998-2003). Of 102 laboratory-confirmed cases in humans from 1997 to 2000, 30% were related to occupational exposures. Recreational exposures were reported in 30% (including traveling abroad in 16%), whereas residential exposure accounted for 37% of the cases. Direct contact with animals, mostly rats and dogs, was observed in 31% of the cases. We conclude that recent changes in transmission patterns of leptospirosis, partially caused by an expanding rat population and the resurgence of canine leptospirosis, may facilitate the spread of the disease in temperate countries like Germany. Preventive measures should be adapted to the changing epidemiology of leptospirosis.
Drug-induced nephrolithiasis: a real-world pharmacovigilance study of the FDA Adverse Event Reporting System
Creators: name: Shen, Yu
name: Yang, Yang
name: Wei, Xinyuan
name: Liang, Jiayu
name: Liu, Zhenhua
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Neuroscience
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer
Science Policy
Mental Health

description: Drug-induced nephrolithiasis is a recognized complication in clinical practice. The objective of this study is to identify drugs that are significantly associated with an increased risk of inducing nephrolithiasis based on the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS). We collected adverse event reports associated with drug-induced nephrolithiasis from the first quarter of 2004 (2004 Q1) to the fourth quarter of 2023 (2023 Q4) in the FAERS database. Subsequently, we applied 4 disproportionality algorithms to evaluate the connection between drugs and nephrolithiasis. A total of 32,788 adverse event reports related to nephrolithiasis with primary suspected drugs were identified. The 50 drugs with the highest frequency and the 40 drugs with the strongest signal were identified and counted. The most frequently occurring drug was adalimumab, while the antiretroviral drug indinavir exhibited the strongest signal intensity. The labels for many of these drugs did not mention the risk of nephrolithiasis. This comprehensive pharmacovigilance study has revealed many drugs potentially associated with an increased risk of nephrolithiasis. Notably, vigilant surveillance for nephrolithiasis risk while using these drugs is crucial in clinical practice.
Additional file 1 of Five point initiative: a community-informed bundled implementation strategy to address HIV in Black communities
Creators: name: Dale, Sannisha K.
name: Etienne, Kayla
name: Hall, Sidny
name: Lazarus, Kimberly
name: Nunnally, Kalenthia
name: Gibson, George
name: Bolden, Roxana
name: Gardner, Nadine
name: Sanders, Jasmyn
name: Reid, Rachelle
name: Phillips, Arnetta
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1.
sj-pdf-6-hpq-10.1177_13591053211014597 – Supplemental material for Financial distress and suicidal behaviour during COVID-19: Family identification attenuates the negative relationship between COVID-related financial distress and mental Ill-health
Creators: name: Stevenson, Clifford
name: Wakefield, Juliet Ruth Helen
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-6-hpq-10.1177_13591053211014597 for Financial distress and suicidal behaviour during COVID-19: Family identification attenuates the negative relationship between COVID-related financial distress and mental Ill-health by Clifford Stevenson and Juliet Ruth Helen Wakefield in Journal of Health Psychology
Additional file 1 of Sex differences in long-term kidney fibrosis following neonatal nephron loss during ongoing nephrogenesis
Creators: name: Menendez-Castro, Carlos
name: Cordasic, Nada
name: Fahlbusch, Fabian B.
name: Woelfle, Joachim
name: Hilgers, Karl F.
name: Hartner, Andrea
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Computational Biology

description: Additional file 1: Supplementary Table 1. List of primers pairs and probes.
Investigating the Need for Drainage Layers in Flexible Pavements
Creators: name: Seyed Mohammad Ghavami, Masoud
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Civil geotechnical engineering
Civil engineering not elsewhere classified
Construction engineering
Engineering practice

description: Moisture can significantly affect flexible pavement performance. As such, it is crucial to remove moisture as quickly as possible from the pavements, mainly to avoid allowing moisture into the pavement subgrade. In the 1990s the Indiana Department of Transportation (INDOT) adopted an asphalt pavement drainage system consisting of an open-graded asphalt drainage layer connected to edge drains and collector pipes to remove moisture from the pavement system. Over the intervening two decades, asphalt pavement materials and designs have dramatically changed in Indiana, and the effectiveness of the pavements drainage system may have changed. Additionally, there are challenges involved in producing and placing open-graded asphalt drainage layers. They can potentially increase costs, and they tend to have lower strength than traditional dense-graded asphalt pavement layers. Given the potential difficulties, the overall objective of this research was to evaluate the effectiveness of the INDOT’s current flexible pavement drainage systems given the changes to pavement cross-sections and materials that have occurred since the open-graded drainage layer was adopted. Additionally, the effectiveness of the filter layer and edge drains were examined.
Laboratory experiments were performed to obtain the hydraulic properties of field-produced asphalt mixture specimens meeting INDOT’s current specifications. The results were used in finite element modeling of moisture flow through pavement sections. Modeling was also performed to investigate the rutting performance of the drainage layers under various traffic loads and subgrade moisture conditions in combination with typical Indiana subgrade soils. The modeling results were used to develop a design tool that can assist the pavement designer in more accurately assessing the need for pavement drainage systems in flexible pavements.
sj-pdf-1-jhs-10.1177_17531934211029511 - Supplemental material for Outcomes of 3-D corrective osteotomies for paediatric malunited both-bone forearm fractures
Creators: name: Roth, Kasper C.
name: van Es, Eline M.
name: Kraan, Gerald A.
name: Verhaar, Jan A. N.
name: Stockmans, Filip
name: Colaris, Joost W.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-jhs-10.1177_17531934211029511 for Outcomes of 3-D corrective osteotomies for paediatric malunited both-bone forearm fractures by Kasper C. Roth, Eline M. van Es, Gerald A. Kraan, Jan A. N. Verhaar, Filip Stockmans and Joost W. Colaris in Journal of Hand Surgery (European Volume)
"It Depends on Who You Talk To": Mapping Writing Center-Writing Program Relationships at Small Liberal Arts Colleges
Creators: name: Towle, Beth A
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Philosophy of language
Educational administration, management and leadership

description: Writing centers and writing programs, as well as the role of their administrators, are shaped by historical and disciplinary factors that have been closely examined by scholars over the last half century. However, the role of institutionality in writing center and writing program administration (WPA) studies has been ignored in much of the scholarship about these two sub-disciplines. This dissertation examines the role of institutionality by developing a new method, relationship-mapping, as a way of understanding how the complex nature of institutional contexts impacts the work of writing centers and writing programs. Through a study of 13 small liberal arts colleges, it is determined that the factors of this specific institution type shape and transform the ways in which centers and programs develop relationships and collaborations to teach and support writing. Relationship-mapping shows promise, though, beyond small colleges and could be used at a multitude of institution types as a way to responsibly critique institutions and how they support students, as well as a way to study institutional cultures of writing.