cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Network Comparison: Embeddings and Interiors
Creators: name: Huang, Weiyu
name: Ribeiro, Alejandro
Publisher: name: arXiv
Year: 2017
Subjects: subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: This paper presents methods to compare networks where relationships between pairs of nodes in a given network are defined. We define such network distance by searching for the optimal method to embed one network into another network, prove that such distance is a valid metric in the space of networks modulo permutation isomorphisms, and examine its relationship with other network metrics. The network distance defined can be approximated via multi-dimensional scaling, however, the lack of structure in networks results in poor approximations. To alleviate such problem, we consider methods to define the interiors of networks. We show that comparing interiors induced from a pair of networks yields the same result as the actual network distance between the original networks. Practical implications are explored by showing the ability to discriminate networks generated by different models.
Green synthesis and characterisation of antioxidant-tagged gold nanoparticle (X-GNP) and studies on its potent antimicrobial activity
Creators: name: Abhishek Bhattacherjee
name: Tanushree Ghosh
name: Abhijit Datta
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Alternanthera philoxeroides (Mart.), a weed, mainly from tropical origin and easily available worldwide. People used to eat it as a food mainly in South Africa. In our previous report we have thoroughly characterise several important phenolics, monoterpene and phenylpropane from methanol soluble fraction of Alternenthera leaves (fraction X) and also reported their α-glucosidase inhibitory, antimicrobial and antioxidant activities. All these isolated natural compounds are well characterised and widely studied. In our present study we try to use this beneficial fraction (named fraction X) in green synthesis of gold nanoparticles (X-GNP). We also try to explore the beneficial aspects of green synthesis in comparison with commonly used chemical synthesis method (GNP) in context with their antimicrobial activity. UV/Vis spectroscopy, DLS, Zeta potential, FT-IR, EDAX and other microscopic techniques namely: SEM, AFM were used to characterise the synthesised nanoparticles. Different important microbial strains were used to evaluate the antimicrobial activity of prepared nanoparticles. Overall the studies suggest successful synthesis of green nanoparticles (X-GNP) and also showed the improvement in antimicrobial activity of X-GNP nanoparticles.
title: Differentialdiagnostik und Therapie des orbitalen Hämangioperizytoms: eine Fallserie
Creators: name: Kolpakov, Vladimir
name: Fischer, T.
name: von Sonnleithner, C.
name: Bertelmann, E.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Hämangioperizytome sind eine Unterform der extrapleuralen solitären fibrösen Tumore und treten in der Orbita als seltene meist intrakonale Raumforderungen auf. Letztere umfassen ein Spektrum von benignem bis zu malignem Wachstum (intermediär maligne). Häufig werden[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Wintertagung der Berlin-Brandenburgischen Augenärztlichen Gesellschaft 2019
Hierarchical star formation across the grand design spiral NGC1566
Creators: name: Gouliermis, Dimitrios A.
name: Elmegreen, Bruce G.
name: Elmegreen, Debra M.
name: Calzetti, Daniela
name: Cignoni, Michele
name: Gallagher, John S.
name: Kennicutt, Robert C.
name: Klessen, Ralf S.
name: Sabbi, Elena
name: Thilker, David
name: Ubeda, Leonardo
name: Aloisi, Alessandra
name: Adamo, Angela
name: Cook, David O.
name: Dale, Daniel
name: Grasha, Kathryn
name: Grebel, Eva K.
name: Johnson, Kelsey E.
name: Sacchi, Elena
name: Shabani, Fayezeh
name: Smith, Linda J.
name: Wofford, Aida
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We investigate how star formation is spatially organized in the grand-design spiral NGC 1566 from deep HST photometry with the Legacy ExtraGalactic UV Survey (LEGUS). Our contour-based clustering analysis reveals 890 distinct stellar conglomerations at various levels of significance. These star-forming complexes are organized in a hierarchical fashion with the larger congregations consisting of smaller structures, which themselves fragment into even smaller and more compact stellar groupings. Their size distribution, covering a wide range in length-scales, shows a power-law as expected from scale-free processes. We explain this shape with a simple "fragmentation and enrichment" model. The hierarchical morphology of the complexes is confirmed by their mass--size relation which can be represented by a power-law with a fractional exponent, analogous to that determined for fractal molecular clouds. The surface stellar density distribution of the complexes shows a log-normal shape similar to that for supersonic non-gravitating turbulent gas. Between 50 and 65 per cent of the recently-formed stars, as well as about 90 per cent of the young star clusters, are found inside the stellar complexes, located along the spiral arms. We find an age-difference between young stars inside the complexes and those in their direct vicinity in the arms of at least 10 Myr. This timescale may relate to the minimum time for stellar evaporation, although we cannot exclude the in situ formation of stars. As expected, star formation preferentially occurs in spiral arms. Our findings reveal turbulent-driven hierarchical star formation along the arms of a grand-design galaxy.
description: Accepted for publication in MNRAS. 23 pages, 18 figures
The impact of rack layout on visual experience in a retail store
Creators: name: Mowrey, Corinne H.
name: Pratik J. Parikh
name: Gue, Kevin R.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Hematology
subject: Plant Biology
subject: FOS: Biological sciences

description: A retail store's layout affects a shopper's visual experience and correspondingly the time spent in the store, navigation through the aisles, and allocation of attention and money across departments and categories. We show that alternate rack layouts allow for more of a rack's facing to appear in the shopper's visual field. To this end, we introduce a set of visual–spatial statistics comprised of visual measures (exposure and intensity) and spatial measures (space and aspect ratio) as a way to quantify the effect a retail layout has on a shopper's visual experience. We present both analytical and algorithmic approaches to capture the dynamics of a travelling shopper's field of regard with respect to a static rack layout. Results for the case of unidirectional shopper travel suggest that racks oriented at 30° from the direction of travel exhibit nearly 250% increase in exposure when compared to 90° racks; for bidirectional traffic, acute orientations still provide up to 150% higher exposure. Interestingly, rack orientations amenable to higher visual measures are not necessarily the best with respect to spatial measures. We illustrate the use of our approach to analyse a real-store layout from a nearby mass merchandiser.
title: Einfluss einer Tamponade auf die Bestrahlung von intraokularen Tumoren
Creators: name: Heufelder, Jens
name: Cordini, D.
name: Stark, R.
name: Weber, A.
name: Riechardt, A.I.
name: Seibel, I.
name: Zeitz, O.
name: Joussen, A.J.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Bei unklaren intraokularen Raumforderungen kann mit Hilfe einer Biopsie im Rahmen einer pars planer Vitrektomie (ppV) eine gesicherte Diagnose erstellt werden. Nach der ppV muss der entfernte Glaskörper je nach Zustand des Auges entweder durch Gas oder Silikonöl ersetzt werden. Ist das Ergebnis[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Wintertagung der Berlin-Brandenburgischen Augenärztlichen Gesellschaft 2019
Additional file 1 of Prognostic and clinicopathological insights of phosphodiesterase 9A gene as novel biomarker in human colorectal cancer
Creators: name: Susmi, Tasmina Ferdous
name: Rahman, Atikur
name: Khan, Md. Moshiur Rahman
name: Yasmin, Farzana
name: Islam, Md. Shariful
name: Nasif, Omaima
name: Alharbi, Sulaiman Ali
name: Batiha, Gaber El-Saber
name: Hossain, Mohammad Uzzal
Publisher: name: figshare
Year: 2021
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Supplementary Table 01: Differential expression analysis of PDE9A in COAD based on different variables using UALCAN database. Supplementary Table 02: PDE9A promoter methylation level based on different variables in COAD from UALCAN database. Supplementary Table 03: The biological relationship between gene expression and survival from PrognoScan database. Supplementary Fig. 01: (A + B) Expression of PDE9A across TCGA cancer with tumor and normal samples from UALCAN database, (C) PDE9A expression profile across all tumor samples and paired normal tissues from GEPIA database (Dot plot, each dots represent expression of samples), (D) PDE9A mRNA expression in normal human tissues based on RNAseq, Microarray, and SAGE using GeneCards database. Supplementary Fig. 02: (A) Heat map of PDE9A expression and DNA methylation status across TCGA Colon cancer sample types from UCSC Xena genome browser, (B) PDE9A expression in different colon cancer DNA methylation clusters from UCSC Xena. Supplementary Fig. 03: Colon cancer tissue subtype profiling analysis for PDE9A gene based on molecular subtype, AJCC stage, Duke stage, Grade, and Histology from Gent2 database. Supplementary Fig. 04: The prognostic value of PDE9A expression on colon cancer. Survival plot from UALCAN database (A) Effect of PDE9A expression level on COAD patient survival; (B) Effect of PDE9A expression level and body weight on COAD patient survival; (C) Effect of PDE9A expression level & Race on COAD patient survival; (D) Effect of PDE9A expression level & gender on COAD patient survival; (E) Survival curve from OncoLnc database, and (F) Kaplan–Meier plot from R2 database in Tumor Colon Adenocarcinoma - TCGA - 286 - rsem - tcgars dataset.
title: Radiogene Optikusneuropathie – was können wir therapeutisch machen?
Creators: name: Seibel, Ira
name: Eckstein, D.
name: Riechardt, A.I.
name: Heufelder, J.
name: Böker, A.
name: Brockmann, C.
name: Zeitz, O.
name: Joussen, A.M.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die radiogene Optikopathie kann nach jeglicher Bestrahlung des Kopf-Hals-Bereichs auftreten, nach direkter Augenbestrahlung ist sie eine bekannte Strahlenkomplikation. Es wurde daher untersucht, ob eine intravitreale Therapie gegenüber einem abwartenden Verhalten Vorteile zeigt. [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Wintertagung der Berlin-Brandenburgischen Augenärztlichen Gesellschaft 2019
Lattice effects on the formation of oxygen vacancies in perovskite thin films
Creators: name: Cazorla, Claudio
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We use first-principles methods to investigate the effects of collective lattice excitations on the formation of oxygen vacancies in perovskite thin films. We find that phonons play a crucial role on the strain-mediated control of defect chemistry at finite temperatures. In particular, zero-temperature oxygen vacancy formation trends deduced as a function of epitaxial strain can be fully reversed near room temperature. Our first-principles calculations evidence a direct link between the lattice contribution to the oxygen vacancy free energy and the volume expansion that the system undergoes when is chemically reduced: The larger the resulting volume expansion, the more favorable thermal excitations are to point defect formation. However, the interplay between the vibrational vacancy entropy, or equivalently, chemical expansion, and epitaxial strain is difficult to generalise as this can be strongly influenced by underlying structural and magnetic transitions. In addition, we find that vacancy ordering can be largely hindered by the thermal lattice excitations.
description: 5 pages, 5 figures
Additional file 1 of Interactive virtual assistance for mental health promotion and self-care management in elderly with type 2 diabetes (IVAM-ED): study protocol and statistical analysis plan for a randomized controlled trial
Creators: name: da Costa, Frederico Ludwig
name: Matzenbacher, Lucas Strassburger
name: Gheno, Vicenzo
name: Brum, Maria Antônia Bertuzzo
name: de Barros, Laura Gomes Boabaid
name: Maia, Isabela Semmelmann
name: Blank, Luiza Machado
name: Fontoura, Lucas Friedrich
name: Alessi, Janine
name: Telo, Gabriela Heiden
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file1: Table S1. SPIRIT Checklist. Table S2. Description of the 28 daily messages repeated every 4 weeks translated to English. Table S3. Description of the 28 daily messages repeated every 4 weeks in Brazilian Portuguese. Table S4. Description of the 7 sets of 14 messages repeated every week translated to English. Table S5. Description of the 7 sets of 14 messages repeated every week translated in Brazilian Portuguese. Table S6. Description of the content featured in the 12 podcast episodes played weekly by the device. Table S7. Logistic and assessments of each visit during the study period. Table S8. Logistic of phone calls during the study period. Table S9. SAP Checklist.
title: 01_2431
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
title: „Liquid biopsy“ – eine Option in der Differentialdiagnose intraokularer Tumoren?
Creators: name: Bornfeld, Norbert
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Mit der Verbesserung der Sequenzierungstechniken für DNA („next generation sequencing“) und der Möglichkeit zellfreie DNA („cell free DNA“: cfDNA) nachzuweisen hat in den letzten Jahren das Interesse am Konzept der „liquid biopsy“ erheblich zugenommen.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Wintertagung der Berlin-Brandenburgischen Augenärztlichen Gesellschaft 2019
Fradkin-Shenker Continuity and "Instead-of-Confinement" Phase
Creators: name: Shifman, M.
name: Yung, A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In 1979 Fradkin and Shenker observed \cite{Frad} that if one considers a Yang-Mills theory fully Higgsed by virtue of scalar fields in the fundamental representation of the ${\rm SU}(N)$ gauge group there is no phase transition in passing from the Higgs regime (weak coupling) to the "QCD confinement" regime at strong coupling. The above two regimes are continuously connected. We combine this observations with lessons from supersymmetric gauge theories which show that the Higgs phase is continuously connected to what is called "instead-of-confinement" phase rather than the phase with quark confinement. In the "instead-of-confinement" phase monopoles are confined and play a role of "constituent" quarks inside hadrons. In contrast, the Seiberg-Witten phase of quark confinement is not analytically connected to the Higgs phase. We propose dedicated lattice studies of Yang-Mills theories with scalar quarks.
description: 16 pages, 2 figures
Somatostatin in Alzheimer's disease: A new Role for an Old Player
Creators: name: Solarski, Michael
name: Hansen Wang
name: Wille, Holger
name: Schmitt-Ulms, Gerold
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The amyloid beta (Aβ) peptide is central to the pathogenesis of Alzheimer's disease (AD). Insights into Aβ-interacting proteins are critical for understanding the molecular mechanisms underlying Aβ-mediated toxicity. We recently undertook an in-depth in vitro interrogation of the Aβ1–42 interactome using human frontal lobes as the biological source material and taking advantage of advances in mass spectrometry performance characteristics. These analyses uncovered the small cyclic neuropeptide somatostatin (SST) to be the most selectively enriched binder to oligomeric Aβ1–42. Subsequent validation experiments revealed that SST interferes with Aβ fibrillization and promotes the formation of Aβ assemblies characterized by a 50–60 kDa SDS-resistant core. The distributions of SST and Aβ overlap in the brain and SST has been linked to AD by several additional observations. This perspective summarizes this body of literature and draws attention to the fact that SST is one of several neuropeptide hormones that acquire amyloid properties before their synaptic release. The latter places the interaction between SST and Aβ among an increasing number of observations that attest to the ability of amyloidogenic proteins to influence each other. A model is presented which attempts to reconcile existing data on the involvement of SST in the AD etiology.
Permutation tests for the equality of covariance operators of functional data with applications to evolutionary biology
Creators: name: Cabassi, Alessandra
name: Pigoli, Davide
name: Secchi, Piercesare
name: Carter, Patrick A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Methodology (stat.ME)
subject: Applications (stat.AP)
subject: FOS: Computer and information sciences
subject: 62G10, 62J15

description: In this paper, we generalize the metric-based permutation test for the equality of covariance operators proposed by Pigoli et al. (2014) to the case of multiple samples of functional data. To this end, the non-parametric combination methodology of Pesarin and Salmaso (2010) is used to combine all the pairwise comparisons between samples into a global test. Different combining functions and permutation strategies are reviewed and analyzed in detail. The resulting test allows to make inference on the equality of the covariance operators of multiple groups and, if there is evidence to reject the null hypothesis, to identify the pairs of groups having different covariances. It is shown that, for some combining functions, step-down adjusting procedures are available to control for the multiple testing problem in this setting. The empirical power of this new test is then explored via simulations and compared with those of existing alternative approaches in different scenarios. Finally, the proposed methodology is applied to data from wheel running activity experiments, that used selective breeding to study the evolution of locomotor behavior in mice.
3D investigations of microscale mixing in helically coiled capillaries
Creators: name: Schuler, Julia
name: Herath, Jakob
name: Kockmann, Norbert
Publisher: name: TU Dortmund
Year: 2021
Subjects: subject: Helically coiled capillary
subject: Micro-computed tomography
subject: Dean flow
subject: Radial mixing
subject: Capillary flow reactor
subject: Local concentration fields
subject: 660

description: In capillary reactors, improving radial mixing and narrowing the residence time distribution is of great importance for high selectivity and reaction performance. A well-known approach is inducing secondary flow patterns by coiling the capillary around a cylinder. To increase understanding of transport phenomena in helically coiled capillaries non-invasive 3D imaging approaches are required. In this perspective paper, we introduce X-ray-based micro-computed tomography for the investigation of dispersion of iodide in a helically coiled tube. The methodology presented here allows for the direct evaluation of radial concentration fields. By varying Dean number Dn and modified torsion parameter T∗, the effect of torsion and curvature on the radial concentration profile can be identified. Detailed knowledge of local radial mixing in helically coiled capillaries will help the precise prediction of reaction progress and selectivity.
description: Journal of flow chemistry;Vol. 11. 2021, Issue 3, pp 217–222
Implications on feature detection when using the benefit–cost ratio
Creators: name: Jagdhuber, Rudolf
name: Rahnenführer, Jörg
Publisher: name: TU Dortmund
Year: 2021
Subjects: subject: Feature costs
subject: Feature detection
subject: Benefit–cost ratio
subject: Feature selection
subject: Cost-sensitive learning
subject: 310

description: In many practical machine learning applications, there are two objectives: one is to maximize predictive accuracy and the other is to minimize costs of the resulting model. These costs of individual features may be financial costs, but can also refer to other aspects, for example, evaluation time. Feature selection addresses both objectives, as it reduces the number of features and can improve the generalization ability of the model. If costs differ between features, the feature selection needs to trade-off the individual benefit and cost of each feature. A popular trade-off choice is the ratio of both, the benefit–cost ratio (BCR). In this paper, we analyze implications of using this measure with special focus to the ability to distinguish relevant features from noise. We perform simulation studies for different cost and data settings and obtain detection rates of relevant features and empirical distributions of the trade-off ratio. Our simulation studies exposed a clear impact of the cost setting on the detection rate. In situations with large cost differences and small effect sizes, the BCR missed relevant features and preferred cheap noise features. We conclude that a trade-off between predictive performance and costs without a controlling hyperparameter can easily overemphasize very cheap noise features. While the simple benefit–cost ratio offers an easy solution to incorporate costs, it is important to be aware of its risks. Avoiding costs close to 0, rescaling large cost differences, or using a hyperparameter trade-off are ways to counteract the adverse effects exposed in this paper.
description: SN computer science;Vol. 2. 2021, Issue 4, Art. No 316
Somatostatin in Alzheimer'S disease: A new Role for an Old Player
Creators: name: Solarski, Michael
name: Hansen Wang
name: Wille, Holger
name: Schmitt-Ulms, Gerold
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The amyloid beta (Aβ) peptide is central to the pathogenesis of Alzheimer's disease (AD). Insights into Aβ-interacting proteins are critical for understanding the molecular mechanisms underlying Aβ-mediated toxicity. We recently undertook an in-depth in vitro interrogation of the Aβ1-42 interactome using human frontal lobes as the biological source material and taking advantage of advances in mass spectrometry performance characteristics. These analyses uncovered the small cyclic neuropeptide somatostatin (SST) to be the most selectively enriched binder to oligomeric Aβ1-42. Subsequent validation experiments revealed that SST interferes with Aβ fibrillization and promotes the formation of Aβ assemblies characterized by a 50–60 kDa SDS-resistant core. The distributions of SST and Aβ overlap in the brain and SST has been linked to AD by several additional observations. This perspective summarizes this body of literature and draws attention to the fact that SST is one of several neuropeptide hormones that acquire amyloid properties before their synaptic release. The latter places the interaction between SST and Aβ among an increasing number of observations that attest to the ability of amyloidogenic proteins to influence each other. A model is presented which attempts to reconcile existing data on the involvement of SST in the AD etiology.
Entanglement of condensed magnons via momentum-space fragmentation
Creators: name: Wong, Clement H.
name: Mizel, Ari
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A scheme is presented for engineering momentum-space entanglement of fragmented magnon condensates. We consider easy plane frustrated antiferromagnets in which the magnon dispersion has degenerate minima that represent umbrella chiral spin textures. With an applied magnetic field, we tune the Hamiltonian near a quantum critical point that is is signaled by a singularity in the entanglement entropy. The ground state develops momentum-space entanglement of the chiral spin textures. The size of the entangled superposition is accessible experimentally through the magnetic structure factor. Our model is motivated by equilibrium magnon condensates in frustrated antiferromagnets such as CsCuCl3, and it can also be simulated in spin-orbit coupled Mott insulators in atomic optical lattices and circuit quantum electrodynamics.
Additional file 1 of Cluster-specific associations between the gut microbiota and behavioral outcomes in preschool-aged children
Creators: name: van de Wouw, Marcel
name: Wang, Yanan
name: Workentine, Matthew L.
name: Vaghef-Mehrabani, Elnaz
name: Barth, Delaney
name: Mercer, Emily M.
name: Dewey, Deborah
name: Arrieta, Marie-Claire
name: Reimer, Raylene A.
name: Tomfohr-Madsen, Lianne
name: Giesbrecht, Gerald F.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1: Figure S1. Gut microbiota clustering using Dirichlet multinomial mixtures. Figure S2. Flowchart of data analysis approach. Figure S3. Differences in stool metabolic pathways between the four clusters. Figure S4. Differences in stool nucleotide levels between the four clusters. Figure S5. Behavioral Symptom scores between the four clusters. Figure S6. Number of microbial taxa that correlate with stool histidine to urocanate turnover. Figure S7. Relationship between Social Skills and urocanate metabolism for participants with low histidine-urocanate turnover rates. Figure S8. Levels of stool urocanate and histidine-urocanate turnover between children with “at risk” and “not at risk” scores for Social Skills and Developmental Social Disorders. Table S1. Sample characteristics of all combined participants. Table S2. PERMANOVA results for stool metabolome beta diversity. Individual independent effects are depicted. Table S3. ANCOVA Results for Adaptive Skill Scores While Correction for Gestational Age at Birth, Birth Weight, Ethnicity and Child Grain Intake. Table S4. ANCOVA Results for Developmental Social Disorder Scores While Correction for Gestational Age at Birth, Birth Weight, Ethnicity and Child Grain Intake. Table S5. ANCOVA Results for Social Skill Scores While Correction for Gestational Age at Birth, Birth Weight, Ethnicity and Child Grain Intake. Table S6. ANCOVA Results for Functional Communication Scores While Correction for Gestational Age at Birth, Birth Weight, Ethnicity and Child Grain Intake. Table S7. ANCOVA Results for Daily Living Scores While Correction for Gestational Age at Birth, Birth Weight, Ethnicity and Child Grain Intake.
Shingle 2.0 manual
Creators: name: Candy, Adam
Publisher: name: figshare
Year: 2017
Subjects: subject: 40403 Geophysical Fluid Dynamics
subject: FOS: Earth and related environmental sciences
subject: Oceanography
subject: 40503 Physical Oceanography
subject: Geometry
subject: Computational Physics
subject: 91501 Computational Fluid Dynamics
subject: FOS: Other engineering and technologies
subject: 10302 Numerical Solution of Differential and Integral Equations
subject: FOS: Mathematics
subject: 80205 Numerical Computation
subject: FOS: Computer and information sciences

description: A manual for the Shingle computational research software library. Further details of this project are available at http://shingleproject.org.
The code is stored in the repository: https://github.com/shingleproject/Shingle
Some of the details of its design are discussed in the paper:https://doi.org/10.5194/gmd-2017-47
Effect of emission of extra lepton pair for precise measurement of W-boson mass
Creators: name: Antropov, Sergii
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the paper we present results for final state emissions of lepton pairs in decays of heavy intermediate states principally of Z boson, but of some importance for the W decays as well. The presented semi-analytical calculation and PHOTOS MC program are in numerical agreement to better than $5\%$ of pair effects. Suggestions for the future works are given.
description: 7 pages, 4 figures. Presented at "XXIII Cracow EPIPHANY Conference", 9 - 12 January 2017, Krakow, Poland. To be published in Acta Physica Polonica B
Towards maintenance and publication of thesauri in controlled vocabulary manager systems
Creators: name: Zapilko, Benjamin
name: Friedrich, Tanja
name: Ghavimi, Behnam
name: Jakowatz, Stefan
name: Mauer, Reiner
name: Müller, Thomas
name: Nugraha, Sigit
name: Klas, Claus-Peter
Publisher: name: Zenodo
Year: 2019

description: A thesaurus is a specific type of a controlled vocabulary which is used to index the content of e.g. publications and research datasets. However, thesauri hold particular relations between terms like related terms and further attributes like scope and editorial notes which are often not part of general controlled vocabularies or systems to maintain them. Moreover, they may be organized in an additional systematic classification. In this presentation, we present a thesaurus manager which addresses additional requirements of thesauri regarding controlled vocabulary manager systems in terms of technical aspects and necessary content-wise changes. The thesaurus manager is based on the CESSDA CV manager and based on the DDI-FlatDB as storage developed by GESIS.
Spin-orbit scattering visualized in quasiparticle interference
Creators: name: Kohsaka, Y.
name: Machida, T.
name: Iwaya, K.
name: Kanou, M.
name: Hanaguri, T.
name: Sasagawa, T.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: In the presence of spin-orbit coupling, electron scattering off impurities depends on both spin and orbital angular momentum of electrons -- spin-orbit scattering. Although some transport properties are subject to spin-orbit scattering, experimental techniques directly accessible to this effect are limited. Here we show that a signature of spin-orbit scattering manifests itself in quasiparticle interference (QPI) imaged by spectroscopic-imaging scanning tunneling microscopy. The experimental data of a polar semiconductor BiTeI are well reproduced by numerical simulations with the $T$-matrix formalism that include not only scalar scattering normally adopted but also spin-orbit scattering stronger than scalar scattering. To accelerate the simulations, we extend the standard efficient method of QPI calculation for momentum-independent scattering to be applicable even for spin-orbit scattering. We further identify a selection rule that makes spin-orbit scattering visible in the QPI pattern. These results demonstrate that spin-orbit scattering can exert predominant influence on QPI patterns and thus suggest that QPI measurement is available to detect spin-orbit scattering.
description: 21 pages, 6 figures
MECOM gene overexpression in pediatric patients with acute myeloid leukemia
Creators: name: Elsherif, Mariam
name: Hammad, Mahmoud
name: Hafez, Hanafy
name: Yassin, Dina
name: Ashraf, Mohamed
name: Yasser, Nouran
name: Lehmann, Leslie
name: Elhaddad, Alaa
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology

description: Acute myeloid leukemia (AML) is characterized by blocked or aberrant differentiation of hematopoietic stem cells. The MECOM gene overexpression in hematopoietic progenitors induces myeloid differentiation block, resulting in increased self-renewal and survival of these transformed progenitors. However, its exact role in AML remains unclear. We aimed to estimate the prevalence of MECOM overexpression among pediatric AML patients, and assess its impact on clinical outcome. Real-time quantitative polymerase chain reaction and Livak method (2ΔΔCt) were used to determine relative MECOM expression level among 243 pediatric patients with AML. MECOM overexpression was considered if the cumulative relative expression was above 1 (2-ΔΔCt) and was designated as MECOMpos. Of 243 AML patients tested 57(23.5%) demonstrated MECOMpos. Patients with MECOMpos had significantly lower median age. The frequency of MECOMpos was significantly higher among AML patients with 11q23 abnormalities, complex karyotypes and among high- and intermediate-risk groups compared to low-risk group (p = .014). MECOMpos patients had significantly lower overall survival (OS) (38.7 vs. 78.9%, p p p = .002) at 36 months compared to MECOMneg patients. Multivariate analysis revealed that MECOMpos was an adverse prognostic factor for OS (hazards ratio (HR) = 2.11, 95% confidence interval (CI) 1.24–3.60, p = .006) and EFS (HR= 1.71, 95% CI 1.07–2.75, p = .025). The logistic regression model showed that MECOMpos was an independent prognostic factor regardless of minimal residual disease status post first induction therapy in the intermediate-risk group (odds ratio 2.89; 95% CI 1.19–6.57, p = .018). The aberrant MECOM gene expression is an adverse prognostic factor, especially in patients without previously known cytogenetic risk factors. Our results suggest the potential benefit from pretreatment screening for MECOM gene overexpression in newly diagnosed AML patients for better risk stratification and treatment adjustment.
Azimuthally differential pion femtoscopy relative to the second and third harmonic in Pb-Pb 2.76 TeV collision from ALICE
Creators: name: Saleh, Mohammad
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Azimuthally differential femtoscopic measurements, being sensitive to spatio-temporal characteristics of the source as well as to the collective velocity fields at freeze-out, provide very important information on the nature and dynamics of the system evolution. While the HBT radii modulations relative to the second harmonic event plane reflect mostly the spatial geometry of the source, the third harmonic results are mostly defined by the velocity fields. Radii variations with respect to the third harmonic event plane unambiguously signal a collective expansion and anisotropy in the flow fields. Event shape engineering (ESE) is a technique proposed to select events corresponding to a particular shape. Azimuthally differential HBT combined with ESE allows for a detailed analysis of the relation between initial geometry, anisotropic flow and the deformation of source shape. We present azimuthally differential pion femtoscopy with respect to second and third harmonic event planes as a function of the pion transverse momentum for different collision centralities in Pb-Pb collisions at sqrt(s_NN) = 2.76 TeV. All these results are compared to existing models. The effects of the selection of the events with high elliptic or triangular flow are also presented.
description: Quark Matter 2017 proceedings
Transverse densities of octet baryons from chiral effective field theory
Creators: name: Alarcón, Jose Manuel
name: Blin, Astrid N. Hiller
name: Weiss, C.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Transverse densities describe the distribution of charge and current at fixed light-front time and provide a frame-independent spatial representation of hadrons as relativistic systems. We calculate the transverse densities of the octet baryons at peripheral distances b = O(M_pi^{-1}) in an approach combining chiral effective field theory (ChEFT) and dispersion analysis. The densities are represented as dispersive integrals of the imaginary parts of the baryon electromagnetic form factors in the timelike region (spectral functions). The spectral functions on the two-pion cut at t > 4 M_pi^2 are computed using relativistic ChEFT with octet and decuplet baryons in the EOMS renormalization scheme. The calculations are extended into the rho-meson mass region, using a dispersive method that incorporates the timelike pion form-factor data. The approach allows us to construct densities at distances b > 1 fm with controlled uncertainties. Our results provide insight into the peripheral structure of nucleons and hyperons and can be compared with empirical densities and lattice-QCD calculations.
description: Proceedings of Light Cone 2016
Development and validation of an HPLC method for the determination of endocrine disruptors bisphenol A and benzophenone in thermochromic printing inks
Creators: name: Kristinka Vinković
name: Rožić, Mirela
name: Galić, Nives
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology

description: The endocrine disruptors bisphenol A (BPA) and benzophenone (BFN) could be important ingredients in thermochromic printing inks in significant amounts. Due to patent protection and use of the inks, manufacturers are not obliged to state their precise chemical composition. These substances in increasingly used thermochromic printing inks present a hazard for human health and environment in the case of inappropriate application and waste disposal. In this work we enabled identification of the inks that contain these hazardous substances by developing a new method for the analysis of BPA and BFN in thermochromic printing inks. The method is based on the reversed-phase liquid chromatography (LC) with UV detection at 226 and 254 nm. Ultrasound-assisted sample extraction in methanol was proven to be the most suitable and effective among several other solvents. The method was completely validated with satisfactory results. The specificity of the method was proven by the additional LC–tandem mass spectrometry analysis. A representative group of 15 ink samples from various manufacturers, curing and printing modes was analyzed. BPA was found in three samples with mass fractions of about 2% while BFN was found in two samples with mass fractions of 0.34 and 0.66%.
Gaia Data Release 1: Validation of the photometry
Creators: name: Evans, D. W.
name: Riello, M.
name: De Angeli, F.
name: Busso, G.
name: van Leeuwen, F.
name: Jordi, C.
name: Fabricius, C.
name: Brown, A. G. A.
name: Carrasco, J. M.
name: Voss, H.
name: Weiler, M.
name: Montegriffo, P.
name: Cacciari, C.
name: Burgess, P.
name: Osborne, P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Aims. The photometric validation of the Gaia DR1 release of the ESA Gaia mission is described and the quality of the data shown. Methods. This is carried out via an internal analysis of the photometry using the most constant sources. Comparisons with external photometric catalogues are also made, but are limited by the accuracies and systematics present in these catalogues. An analysis of the quoted errors is also described. Investigations of the calibration coefficients reveal some of the systematic effects that affect the fluxes. Results. The analysis of the constant sources shows that the early-stage photometric calibrations can reach an accuracy as low as 3 mmag.
Discovering the Building Blocks of Atomic Systems using Machine Learning
Creators: name: Rosenbrock, Conrad W.
name: Homer, Eric R.
name: Csányi, Gábor
name: Hart, Gus L. W.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Machine learning has proven to be a valuable tool to approximate functions in high-dimensional spaces. Unfortunately, analysis of these models to extract the relevant physics is never as easy as applying machine learning to a large dataset in the first place. Here we present a description of atomic systems that generates machine learning representations with a direct path to physical interpretation. As an example, we demonstrate its usefulness as a universal descriptor of grain boundary systems. Grain boundaries in crystalline materials are a quintessential example of a complex, high-dimensional system with broad impact on many physical properties including strength, ductility, corrosion resistance, crack resistance, and conductivity. In addition to modeling such properties, the method also provides insight into the physical "building blocks" that influence them. This opens the way to discover the underlying physics behind behaviors by understanding which building blocks map to particular properties. Once the structures are understood, they can then be optimized for desirable behaviors.
description: 8 pages, 4 figures, 1 table
Hydrogen storage and compression
Creators: name: Makridis, Sofoklis
Publisher: name: arXiv
Year: 2017
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Popular Physics (physics.pop-ph)
subject: FOS: Physical sciences

description: Energy has always been the driving force in the technological and economic development of societies. The consumption of a significant amount of energy is required to provide basic living conditions of developed countries (heating, transportation, lighting, etc.). Today energy supply has a considerable impact on the environment, since it is fuelled by the burning of fossil fuels. In addition to this, the fossil fuel reserves are decreasing while the demand for energy is rapidly rising. Climate change, the depletion and geographical segregation of fossil fuel resources, health related issues as well as energy poverty constitute the driving forces towards the pursuit of alternative energy sources. In addition, countries with no access to oil reserves are being dependent from other countries for their energy supply, with a strong impact on politics and financial issues.
On D.Y. Gao and X. Lu paper "On the extrema of a nonconvex functional with double-well potential in 1D"
Creators: name: Zalinescu, Constantin
Publisher: name: arXiv
Year: 2016
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 35J20, 35J60, 74G65, 74S30

description: The aim of this paper is to discuss the main result in the paper by D.Y. Gao and X. Lu [On the extrema of a nonconvex functional with double-well potential in 1D, Z. Angew. Math. Phys. (2016) 67:62]. More precisely we provide a detailed study of the problem considered in that paper, pointing out the importance of the norm on the space $C^{1}[a,b]$; because no norm (topology) is mentioned on $C^{1}[a,b]$ we look at it as being a subspace of $W^{1,p}(a,b)$ for $p\in [1,\infty]$ endowed with its usual norm. We show that the objective function has not local extrema with the mentioned constraints for $p\in [1,4)$, and has (up to an additive constant) only a local maximizer for $p=\infty$, unlike the conclusion of the main result of the discussed paper where it is mentioned that there are (up to additive constants) two local minimizers and a local maximizer. We also show that the same conclusions are valid for the similar problem treated in the preprint by X. Lu and D.Y. Gao [On the extrema of a nonconvex functional with double-well potential in higher dimensions, arXiv:1607.03995].
description: 12 pages; in this version we added the forgotten condition $F(x) \ne 0$ for $x\in (a,b)$ on page 3