cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2 of The extracellular HDAC6 ZnF UBP domain modulates the actin network and post-translational modifications of Tau
Creators: name: Balmik, Abhishek Ankur
name: Sonawane, Shweta Kishor
name: Chinnathambi, Subashchandrabose
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Supplementary figure 1. HDAC6 ZnF UBP treatment to neuro2a cells does not have a toxic effect. A) Amino acid sequence of human HDAC6 Zinc finger ubiquitin-binding domain. This domain is located on the C-terminal of HDAC6 and associates with polyubiquitinated protein aggregates to mediate the formation of aggresomes. B) MTT assay was carried out to determine the viability of neuro2a upon HDAC6 ZnF UBP treatment. Neuroblastoma cells treated with HDAC6 at different concentrations show minimum toxicity and maintain viability at 80% at highest concentration of 500 nM. C) LDH release assay determines the damage to the cell membrane upon exposure to test molecule. The membrane leakage assay (LDH assay) shows that HDAC6 does not disrupt the cell membrane and affect cell viability. D) Apoptosis rate of neuro2a cells upon HDAC6 ZnF UBP treatment was assayed using Caspase-3 assay. Caspase-3 assay shows increased levels of caspase-3 with successive time interval but do not differ from control samples. Statistical significance determined by two-tailed unpaired t-test. (n.s. – non-significant, * indicates P ≤0.05, ** indicates P ≤ 0.01, *** indicates P ≤ 0.001). Supplementary figure 2. Internalization of HDAC6 ZnF UBP in neuro2a. Neuro2a cells treated with HDAC6 ZnF UBP (20-500 nM) were mapped by antibody against HDAC6 and anti His-tag antibody to determine the internalization of 14 KDa HDAC6 ZnF UBP domain in cells. Supplementary figure 3. Co-localization of actin and tubulin in neuro2a. A) Immunostaining for β-actin and tubulin was performed to examine their localization in HDAC6 ZnF UBP treated neuro2a cells. Actin and tubulin co-localizes in the neuronal extensions in both treated and untreated cells. However, tubulin was found to be localized more in MTOC in case of HDAC6 treatment. B) Orthogonal projection images for actin and tubulin shows both actin and tubulin in untreated control cells while differential localization of tubulin in HDAC6 treated cells. Supplementary figure 4. DIC for neurite extensions in HDAC6 ZnF UBP treated cells. HDAC6 ZnF UBP treated cells showed enhancement in actin regulated membrane extensions in the form of podosomes, lamellipodia and podonuts. DIC images for untreated and HDAC6 treated groups indicate marked difference in the pattern of their membrane extensions.
Two-Phase Dynamics of DNA Supercoiling based on DNA Polymer Physics
Creators: name: Wan, Biao
name: Yu, Jin
Publisher: name: arXiv
Year: 2021
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: DNA supercoils are generated in genome regulation processes such as transcription and replication, and provide mechanical feedback to such processes. Under tension, DNA supercoil can present a coexistence state of plectonemic (P) and stretched (S) phases. Experiments have revealed the dynamic behaviors of plectoneme, e.g. diffusion, nucleation and hopping. To represent these dynamics with computational changes, we demonstrated first the fast dynamics on the DNA to reach torque equilibrium within the P and S phases, and then identified the two-phase boundaries as collective slow variables to describe the essential dynamics. According to the time scale separation demonstrated here, we accordingly developed a two-phase model on the dynamics of DNA supercoiling, which can capture physiologically relevant events across time scales of several orders of magnitudes. In this model, we systematically characterized the slow dynamics between the two phases, and compared the numerical results with that from the DNA polymer physics-based worm-like chain model. The supercoiling dynamics, including the nucleation, diffusion, and hopping of plectoneme, have been well represented and reproduced, using the two-phase dynamic model, at trivial computational costs. Our current developments, therefore, can be implemented to explore multi-scale physical mechanisms of the DNA supercoiling-dependent physiological processes.
Production and Decay of Scalar Stoponium Bound States
Creators: name: Drees, M.
name: Nojiri, M. M.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this paper we discuss possible signatures for the production of scalar \stst\ (stoponium) bound states \sigst\ at hadron colliders, where \st\ is the lighter scalar top eigenstate. We first study the decay of \sigst; explicit expressions are given for all potentially important decay modes. If \st\ has unsuppressed two--body decays, they will always overwhelm the annihilation decays of \sigst. Among the latter, we find that usually either the $gg$ or $hh$ final state dominates, depending on the size of the off--diagonal entry of the stop mass matrix; $h$ is the lighter neutral scalar Higgs boson of the minimal supersymmetric model. If \msig\ happens to be close to the mass of one of the neutral scalar Higgs bosons, $Q \bar{Q}$ final states dominate ($Q=b$ or $t$). \ww\ and $ZZ$ final states are subdominant. We argue that $\sigst \rightarrow \gamgam$ decays offer the best signal for stoponium production at hadron colliders. The tevatron should be able to close the light stop window left open by LEP searches, but its mass reach is limited to $\msig \leq 90$ GeV. In contrast, at the LHC one should ultimately be able to probe the region $\msig \leq 700$ GeV, if the $hh$ partial width is not too large. We also comment on the feasibility of searching for \sigst\ production at hadron colliders in the $ZZ, \ Z γ$ and \fourtau\ final states, and briefly mention \sigst\ production at \gamgam\ colliders.
description: 31 pages plus 10 figures (available from DREES@WISCPHEN); LaTeX with equation.sty; MAD/PH/808, KEK-TH-379
Oral health and human papillomavirus-associated head and neck squamous cell carcinoma
Creators: name: Mazul, A.L.
name: Abedi-Ardekani, B.
name: Taylor, J.M.
name: Olshan, A.F.
name: Divaris, K.
name: Weissler, M.C.
name: Zevallos, J.P.
name: Brennan, P.
name: Anantharaman, D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: BACKGROUND: Indicators of poor oral health, including smoking, have been associated with increased risk of head and neck squamous cell carcinoma, especially oropharyngeal squamous cell carcinoma (OPSCC), yet few studies have examined whether this association is modified by human papillomavirus (HPV) status. METHODS: Data from interviews and tumor HPV status from a large population-based case-control study, the Carolina Head and Neck Cancer Study (CHANCE), were used to estimate the association between oral health indicators and smoking among 102 HPV-positive patients and 145 HPV-negative patients with OPSCC and 1396 controls. HPV status was determined by p16INK4a (p16) immunohistochemistry. Unconditional, multinomial logistic regression was used to estimate odds ratios (ORs) for all oral health indictors adjusting for important covariates. RESULTS: Routine dental examinations were associated with a decreased risk of both HPV-negative OPSCC (OR, 0.52; 95% confidence interval [CI], 0.35-0.76) and HPV-positive OPSCC (OR, 0.55; 95% CI, 0.36-.86). Tooth mobility (a proxy for periodontal disease) increased the risk of HPV-negative disease (OR, 1.70; 95% CI, 1.18-2.43) slightly more than the risk for HPV-positive disease (OR, 1.45; 95% CI, 0.95-2.20). Ten or more pack-years of cigarette smoking were strongly associated with an increased risk of HPV-negative OPSCC (OR, 4.26; 95% CI, 2.85-6.37) and were associated less with an increased risk of HPV-positive OPSCC (OR, 1.62; 95% CI, 1.10-2.38). CONCLUSIONS: Although HPV-positive and HPV-negative HNSCC differ significantly with respect to etiology and tumorigenesis, the current findings suggest a similar pattern of association between poor oral health, frequency of dental examinations, and both HPV-positive and HPV-negative OPSCC. Future research is required to elucidate interactions between poor oral health, tobacco use, and HPV in the development of OPSCC. Cancer 2017;71–80. © 2016 American Cancer Society.
Effects of Multiple Inputs with an Accent Cue in Speech Segmentation Facilitated by Language Experiences
Creators: name: Haesung  Kim
Publisher: name: Carnegie Mellon University
Year: 2012
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Past studies using artificial language speech streams showed that adults use statistics to correctly segment words. However, these studies mostly used only a single stream input and monolingual populations. Given the number of bilinguals and the prevalence of exposures to multiple languages, how do monolinguals and bilinguals compare in speech segmentation task given multiple inputs? Speech segmentation becomes challenging with multiple inputs when learners combine input across languages. The statistics of particular units that overlap different languages may change and hinder correct segmentation. Current study addresses this question by using two interleaved artificial language streams and an indexical accent cue. In the study, participants were asked to segment two artificial language streams with or without an accent cue. Our results indicated that in the absent of the accent cue, bilinguals and monolinguals performed similar, while monolinguals’ performance was weakened compared to those of bilinguals in the presence of the accent cue. Weakened performance can be due to two accounts: switching of accents and difficulty of languages. This study, expanding Weiss et al. (2009) and bilingualism research, informs us that the level of difficulty of languages and cues can play a role in segmenting multiple language streams.
A kinetic model of a polyelectrolyte gel undergoing phase separation
Creators: name: Celora, Giulia L.
name: Hennessy, Matthew G.
name: Münch, Andreas
name: Wagner, Barbara
name: Waters, Sarah L.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: In this study we use non-equilibrium thermodynamics to systematically derive a phase-field model of a polyelectrolyte gel coupled to a hydrodynamic model for a salt solution surrounding the gel. The governing equations for the gel account for the free energy of the internal interfaces which form upon phase separation, the nonlinear elasticity of the polyelectrolyte network, and multi-component diffusive transport following a Stefan--Maxwell approach. The time-dependent model describes the evolution of the gel across multiple time and spatial scales and so is able to capture the large-scale solvent flux and the emergence of long-time pattern formation in the system. We explore the model for the case of a constrained gel undergoing uni-axial deformations. Numerical simulations show that rapid changes in the gel volume occur once the volume phase transition sets in, as well as the triggering of spinodal decomposition that leads to strong inhomogeneities in the lateral stresses, potentially leading to experimentally visible patterns.
Active smoking and survival following breast cancer among African American and non-African American women in the Carolina Breast Cancer Study
Creators: name: Olshan, A.F.
name: Conway, K.
name: Parada, H., Jr.
name: Sun, X.
name: Tse, C.-K.
name: Troester, M.A.
Publisher: name: Springer Science and Business Media Deutschland GmbH
Year: 2017

description: Purpose: To examine racial differences in smoking rates at the time of breast cancer diagnosis and subsequent survival among African American and non-African American women in the Carolina Breast Cancer Study (Phases I/II), a large population-based North Carolina study. Methods: We interviewed 788 African American and 1,020 Caucasian/non-African American women diagnosed with invasive breast cancer from 1993 to 2000, to assess smoking history. After a median follow-up of 13.56 years, we identified 717 deaths using the National Death Index; 427 were breast cancer-related. We used Cox regression to examine associations between self-reported measures of smoking and breast cancer-specific survival within 5 years and up to 18 years after diagnosis conditional on 5-year survival. We examined race and estrogen receptor status as potential modifiers. Results: Current (vs never) smoking was not associated with 5-year survival; however, risk of 13 year conditional breast cancer-specific mortality was elevated among women who were current smokers at diagnosis (HR 1.54, 95% CI 1.06–2.25), compared to never smokers. Although smoking rates were similar among African American (22.0%) and non-African American (22.1%) women, risk of breast cancer-specific mortality was elevated among African American (HR 1.69, 95% CI 1.00–2.85), but only weakly elevated among non-African American (HR 1.22, 95% CI 0.70–2.14) current (vs. never) smokers (PInteraction = 0.30). Risk of breast cancer-specific mortality was also elevated among current (vs never) smokers diagnosed with ER− (HR 2.58, 95% CI 1.35–4.93), but not ER+ (HR 1.11, 95% CI 0.69–1.78) tumors (PInteraction = 0.17). Conclusions: Smoking may negatively impact long-term survival following breast cancer. Racial differences in long-term survival, as related to smoking, may be driven by ER status, rather than by differences in smoking patterns.
ОБИДЖОН МАҲМУДОВ ВА УНИНГ ФАОЛИЯТИ, ЖАДИДЧИЛИК ҲАРАКАТИГА ОИД ҚАРАШЛАРИ
Creators: name: Воҳидова, Комила
Publisher: name: Zenodo
Year: 2024

description: XIX аср охири, ХХ аср бошларида Россия мустамлакаси ҳисобланган Польша, Қрим каби Туркистон ижтимоий ҳаётида  ҳам янгиланиш, ривожланиш ва тараққиётга эришиш мақсадида юзага келган ҳаракат Туркистон тарихида жадидчилик ҳаракати сифатида ном олади. Мақолада ушбу ҳаракатнинг машҳур намояндаларидан бири, нафақат Фарғона водийсида, балки  Туркистонда ҳам кўзга кўринган миллий зиёлилардан бири бўлган, жадид мутафаккири Обиджон Маҳмудовнинг ҳаёт йўли ва XIX аср охири, ХХ аср бошларида Туркистон ижтимоий ҳаётида юзага келган муаммоларга нисбатан янгича қарашлари, олиб борган фаолияти, нашриёти ҳамда, унинг томонидан нашр этилган “Садойи Фарғона” газетасига оид маълумотлар тадқиқ этилади.
Bias and variance of the Bayesian-mean decoder
Creators: name: Prat-Carrabin, Arthur
name: Woodford, Michael
Publisher: name: arXiv
Year: 2021
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences

description: Perception, in theoretical neuroscience, has been modeled as the encoding of external stimuli into internal signals, which are then decoded. The Bayesian mean is an important decoder, as it is optimal for purposes of both estimation and discrimination. We present widely-applicable approximations to the bias and to the variance of the Bayesian mean, obtained under the minimal and biologically-relevant assumption that the encoding results from a series of independent, though not necessarily identically-distributed, signals. Simulations substantiate the accuracy of our approximations in the small-noise regime. The bias of the Bayesian mean comprises two components: one driven by the prior, and one driven by the precision of the encoding. If the encoding is 'efficient', the two components have opposite effects; their relative strengths are determined by the objective that the encoding optimizes. The experimental literature on perception reports both 'Bayesian' biases directed towards prior expectations, and opposite, 'anti-Bayesian' biases. We show that different tasks are indeed predicted to yield such contradictory biases, under a consistently-optimal encoding-decoding model. Moreover, we recover Wei and Stocker's "law of human perception", a relation between the bias of the Bayesian mean and the derivative of its variance, and show how the coefficient of proportionality in this law depends on the task at hand. Our results provide a parsimonious theory of optimal perception under constraints, in which encoding and decoding are adapted both to the prior and to the task faced by the observer.
description: Accepted at NeurIPS 2021. 12 pages, 2 figures. Supplementary Materials: 7 pages, 1 figure
Fabrication of high performance MgB2 wires by an internal Mg diffusion process
Creators: name: Hur, J. M.
name: Togano, K.
name: Matsumoto, A.
name: Kumakura, H.
name: Wada, H.
name: Kimura, K.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We succeeded in the fabrication of high-Jc MgB2/Fe wires applying the internal Mg diffusion (IMD) process with pure Mg core and SiC addition. A pure Mg rod with 2 mm diameter was placed at the center of a Fe tube, and the space between Mg and Fe tube was filled with B powder or the powder mixture of B-(5mol%)SiC. The composite was cold worked into 1.2mm diameter wire and finally heat treated at temperatures above the melting point of Mg(~650oC). During the heat treatment liquid Mg infiltrated into B layer and reacted with B to form MgB2. X-ray diffraction analysis indicated that the major phase in the reacted layer is MgB2. SEM analysis shows that the density of MgB2 layer is higher than that of usual powder-in-tube(PIT) processed wires. The wires with 5mol% SiC addition heat treated at 670oC showed Jc values higher than 105A/cm2 in 8T and 41,000A/cm2 in 10T at 4.2K. These values are much higher than those of usual PIT processed wires even compared to the ones with SiC addition. Higher density of MgB2 layer obtained by the diffusion reaction is the major cause of this excellent Jc values.
description: 7page, 6figures
title: ADCO, Grènetier de Cîteaux : comptes (1499-1503) (11 H 1173), f. 00433
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes

description: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173), f. 00433, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Manipulating Anomalous Hall Antiferromagnets with Magnetic Fields
Creators: name: Chen, Hua
name: Wang, Tzu-Cheng
name: Xiao, Di
name: Guo, Guang-Yu
name: Niu, Qian
name: MacDonald, Allan H.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The symmetry considerations that imply a non-zero anomalous Hall effect (AHE) in certain non-collinear antiferromagnets also imply both non-zero orbital magnetization and a net spin magnetization. We have explicitly evaluated the orbital magnetizations of several anomalous Hall effect antiferromagnets and find that they tend to dominate over spin magnetizations, especially so when spin-orbit interactions are weak. Because of the greater relative importance of orbital magnetization the coupling between magnetic order and an external magnetic field is unusual. We explain how magnetic fields can be used to manipulate magnetic configurations in these systems, pointing in particular to the important role played by the response of orbital magnetization to the Zeeman-like spin exchange fields.
description: 5 pages + supplementary materials; revised version
title: A large-scale survey of X-ray filaments in the Galactic Centre
Creators: name: Johnson, SP
name: Dong, H
name: Wang, QD
Publisher: name: University of Massachusetts Amherst
Year: 2009
Subjects: subject: * pulsars: general; * ISM: magnetic fields; * supernova remnants; * Galaxy: centre; * X-rays: ISM; * X-rays: stars
subject: Astrophysics and Astronomy

description: This is the pre-published version harvested from ArXiv. The published version is located at http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2966.2009.15362.x/abstract;jsessionid=F578CE93C816898AEA8548306BF8A358.d03t03
description: We present a catalogue of 17 filamentary X-ray features located within a 68 × 34 arcmin2 view centred on the Galactic Centre region from images taken by Chandra. These features are described by their morphological and spectral properties. Many of the X-ray features have non-thermal spectra that are well fitted by an absorbed power law. Of the 17 features, we find six that have not been previously detected, four of which are outside the immediate 20 × 20 arcmin2 area centred on the Galactic Centre. Seven of the 17 identified filaments have morphological and spectral properties expected for pulsar wind nebulae (PWNe) with X-ray luminosities of 5 × 1032 to 1034 erg s−1 in the 2.0–10.0 keV band and photon indices in the range of Γ= 1.1 to 1.9. In one feature, we suggest the strong neutral Fe Kα emission line to be a possible indicator for past activity of Sgr A*. For G359.942−0.03, a particular filament of interest, we propose the model of a ram pressure confined stellar wind bubble from a massive star to account for the morphology, spectral shape and 6.7 keV He-like Fe emission detected. We also present a piecewise spectral analysis on two features of interest, G0.13−0.11 and G359.89−0.08, to further examine their physical interpretations. This analysis favours the PWN scenario for these features.
Effects of Mate Value Difference on Relationship Length and Satisfaction
Creators: name: DeIuliis, Sarah
Publisher: name: Carnegie Mellon University
Year: 2013
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: The field of evolutionary psychology emphasizes the specialized psychological mechanisms that are present in humans that developed under the adaptive pressures of evolution faced by our ancestors. One major adaptive pressure that has been studied extensively involves mating and mate selection. Many studies have been performed which identified, and subsequently confirmed, that humans have a preference for certain traits and that these mate preferences are seen across the world, regardless of culture (e.g.: Buss & Barnes, 1986; Buss, 1989; Shackelford, Schmitt, & Buss, 2005; Stone, Shackelford, & Buss, 2007). Research has also been conducted on ―mate value,‖ the extent to which a person possessed these preferred traits and, consequently, how desirable they are as a mate (e.g.: Kenrick, Neuberg, Zierk, & Krones, 1994; Gutierres, Kenrick, & Partch, 1999; Buston & Emlen, 2003). Mate value is, for instance, one determining factor in mate choice because one’s options may be broadened or narrowed as a result of one’s mate value—highly desirable individuals can afford to be more choosy regarding a potential mate because they are valued highly by many, whereas individuals with low mate value are perceived as having less to offer and will likely have to settle when choosing a mate. Although much is known and has been studied concerning mate preferences and mate value, such as the above studies, research concerning differences in mate value between partners is lacking. The goal of the experiments reported here was to investigate if the difference in mate value of a couple has an effect on the predicted length of their relationship.
Additional file 1 of Whole genome sequencing in oncology: using scenario drafting to explore future developments
Creators: name: van de Ven, Michiel
name: Simons, Martijn J. H. G.
name: Koffijberg, Hendrik
name: Joore, Manuela A.
name: IJzerman, Maarten J.
name: Retèl, Valesca P.
name: van Harten, Wim H.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Appendix.
Effects of Federal Statutory Minimum Sentencing Laws on Plea Bargain Outcomes
Creators: name: Abrams, Meredith
Publisher: name: Carnegie Mellon University
Year: 2016
Subjects: subject: 160699 Political Science not elsewhere classified
subject: FOS: Political science

description: Mandatory minimum sentencing laws and plea bargaining are two vital elements of the United States justice system. Lacking from current literature is a formal exploration of whether or not the existence of one has a causal relationship with the other. Whether or not the existence of mandatory minimums sentencing laws makes a difference in the plea bargain decision making process of defendants is an important research question that is addressed here. To provide a foundation of understanding of the current state of research on both plea bargains and mandatory minimums, a literature review will cover several different formulations of plea bargain decision making, including a shadow of trial model, econometric models, and game theory models, as well as other viewpoints examining plea bargains as a collective action problem among defendants, and a market to be regulated. Literature on mandatory minimums delves into the history of their enactment, the original motivations and rationales for imposing them, their effectiveness in achieving those goals, and the current state of how mandatory minimums are imposed across the country. Additional literature examines the connection between the two, insofar as it has been studied previously
Measurement of D$^0$, D$^+$, D$^{*+}$ and D$^+_{\rm s}$ production in Pb-Pb collisions at $\mathbf{\sqrt{s_{\rm NN}}}= 5.02$ TeV
Creators: name: ALICE Collaboration
Publisher: name: arXiv
Year: 2018
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We report measurements of the production of prompt D$^0$, D$^+$, D$^{*+}$ and D$^+_{\rm s}$ mesons in Pb-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair $\sqrt{s_{\rm NN}}=5.02$ TeV, in the centrality classes 0-10%, 30-50% and 60-80%. The D-meson production yields are measured at mid-rapidity ($|y|<0.5$) as a function of transverse momentum ($p_{\rm T}$). The $p_{\rm T}$ intervals covered in central collisions are: $1 8$ GeV/$c$, while it is larger at lower $p_{\rm T}$. The nuclear modification factors for strange and non-strange D mesons are also compared to theoretical models with different implementations of in-medium energy loss.
description: 35 pages, 10 captioned figures, 2 tables, authors from page 25, published, figures at http://aliceinfo.cern.ch/ArtSubmission/node/4251
Light Fermion Masses in Superstring Derived Standard--like Models
Creators: name: Faraggi, Alon E.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: I discuss the suppression of the lightest generation fermion mass terms in realistic superstring standard--like models in the free fermionic formulation. The suppression of the mass terms is a consequence of horizontal symmetries that arise due to the $Z_2\times Z_2$ orbifold compactification. In a specific model I investigate the possibility of resolving the strong CP puzzle by a highly suppressed up quark mass. In some scenarios the up quark mass may be as small as $10^{-8}MeV$. I show that in the specific model the suppression of the up quark mass is incompatible with the requirement of a nonvanishing electron mass. I discuss how this situation may be remedied.
description: IASSNS-93/82, 16 pages, uses phyzzx
Investigating associations between health-related quality of life and endocrine therapy underuse in women with early-stage breast cancer
Creators: name: Pinheiro, L.C.
name: Reeve, B.B.
name: Olshan, A.F.
name: Samuel, C.A.
name: Reeder-Hayes, K.E.
name: Wheeler, S.B.
Publisher: name: Oxford University Press
Year: 2017

description: Purpose Endocrine therapy (ET) underuse puts women at increased risk for breast cancer (BC) recurrence. Our objective was to determine if health-related quality of life (HRQOL) subgroups were associated with underuse. Methods Data came from the third phase of the Carolina Breast Cancer Study. We included 1,599 women with hormone receptor-positiveBCage 20 to 74 years.HRQOLwas measured, on average,5months postdiagnosis. Subgroups were derived using latent profile (LP) analysis. Underuse was defined as not initiating or adhering to ET by 36 months postdiagnosis. Multivariable logistic regression models estimated adjusted odds ratios (ORs) between HRQOL LPs and underuse. The best HRQOL LP was the reference. Chemotherapy- and race-stratified models were estimated, separately. Results Initiation analyses included 953womenwhohad not begun ET by their 5-month survey. Of these, 154 never initiated ET. Adherence analyses included 1,114 ET initiators, of whom 211 were nonadherent.HRQOLwas not significantly associated with noninitiation, except among nonchemotherapy users, with membership in the poorest LP associated with increased odds of noninitiation (adjusted OR, 5.5; 95% CI, 1.7 to 17.4). Membership in the poorest LPs was associated with nonadherence (LP1: adjusted OR, 2.2; 95% CI, 1.2 to 4.0 and LP2: adjusted OR,1.9;95%CI, 1.1 to 3.6). Membershipin the poorestLPwasassociated with nonadherence among nonchemotherapy users (adjusted OR, 2.1; 95% CI, 1.2 to 5.1). Conclusion Ourresults suggestwomenwith poorHRQOLduring active treatmentmaybe at increased risk for ET underuse. Focusing on HRQOL, a modifiable factor, may improve targeting of future interventions early in theBCcontinuum to improve ET initiation and adherence and prevent BC recurrence.
title: Affiche workshop projet ONGUENT Goudrons végétaux médicinaux en Méditerranée: ressources, production, usages et bioactivité 2017
Creators: name: LabexMed
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2019

description: Affiche du workshop organisé pour le projet ONGUENT Goudrons végétaux médicinaux en Méditerranée: ressources, production, usages et bioactivité.
Projet de recherche porté par Sylavain Burri (LA3M UMR 7298).
Additional file 1 of Weight and waist-to-hip ratio change pattern during the first five years of survival: data from a longitudinal observational Chinese breast cancer cohort
Creators: name: Lei, Yuan-Yuan
name: Ho, Suzanne C.
name: Kwok, Carol
name: Cheng, Ashley
name: Cheung, Ka Li
name: Lee, Roselle
name: Mo, Frankie
name: Yeo, Winnie
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1; Supplementary Table 1. The demographic, clinical and lifestyle characteristics collected at T0 assessment among patients who were loss to follow-up at T1, T2, and T3. Supplementary Fig. 1 Distribution of patients’ BMI at diagnosis, T1, T2 and T3 assessment using the WHO guideline for international use. Abbreviation: BMI, body mass index; WHO, World Health Organization
Marchenko-Ostrovski mappings for periodic Jacobi matrices
Creators: name: Korotyaev, Evgeny
name: Kutsenko, Anton
Publisher: name: arXiv
Year: 2007
Subjects: subject: Mathematical Physics (math-ph)
subject: Spectral Theory (math.SP)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We consider the 1D periodic Jacobi matrices. The spectrum of this operator is purely absolutely continuous and consists of intervals separated by gaps. We solve the inverse problem (including characterization) in terms of vertical slits on the quasimomentum domain . Furthermore, we obtain a priori two-sided estimates for vertical slits in terms of Jacoby matrices.
Dietary fiber intake and head and neck cancer risk: A pooled analysis in the International Head and Neck Cancer Epidemiology consortium
Creators: name: Turati, F.
name: Winn, D.M.
name: Boffetta, P.
name: Chuang, S.-C.
name: Zevallos, J.P.
name: Lee, Y.-C.A.
name: Edefonti, V.
name: Olshan, A.F.
name: Kawakita, D.
name: Hashibe, M.
name: Yu, G.-P.
name: Matsuo, K.
name: Morgenstern, H.
name: Ferraroni, M.
name: La Vecchia, C.
name: Bosetti, C.
name: Garavello, W.
name: Decarli, A.
name: Zhang, Z.-F.
name: Kelsey, K.
name: McClean, M.
name: Moysich, K.
name: Levi, F.
name: Serraino, D.
name: Parpinel, M.
name: Schantz, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The possible role of dietary fiber in the etiology of head neck cancers (HNCs) is unclear. We used individual-level pooled data from ten case-control studies (5959 cases and 12,248 controls) participating in the International Head and Neck Cancer Epidemiology (INHANCE) consortium, to examine the association between fiber intake and cancer of the oral cavity/pharynx and larynx. Odds Ratios (ORs) and their 95% Confidence Intervals (CIs) were estimated using unconditional multiple logistic regression applied to quintile categories of non-alcohol energy-adjusted fiber intake and adjusted for tobacco and alcohol use and other known or putative confounders. Fiber intake was inversely associated with oral and pharyngeal cancer combined (OR for 5th vs. 1st quintile category = 0.49, 95% CI: 0.40–0.59; p for trend <0.001) and with laryngeal cancer (OR = 0.66, 95% CI: 0.54–0.82, p for trend <0.001). There was, however, appreciable heterogeneity of the estimated effect across studies for oral and pharyngeal cancer combined. Nonetheless, inverse associations were consistently observed for the subsites of oral and pharyngeal cancers and within most strata of the considered covariates, for both cancer sites. Our findings from a multicenter large-scale pooled analysis suggest that, although in the presence of between-study heterogeneity, a greater intake of fiber may lower HNC risk.
Enhanced Visualization and Interpretation of XMCD‐PEEM Data Using SOM‐RPM Machine Learning
Creators: name: Wong, See Yoong
name: Harmer, Sarah L
name: Gardner, Wil
name: Schenk, Alex
name: Ballabio, Davide
name: Pigram, Paul
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 4016
subject: Materials engineering
subject: FOS: Materials engineering
classificationCode: 3403
subject: Macromolecular and materials chemistry
classificationCode: 5104
subject: Condensed matter physics

description: Abstract: Photoemission electron microscopy (PEEM) is a powerful technique for surface characterization that provides detailed information on the chemical and structural properties of materials at the nanoscale. In this study, the potential is explored using a machine learning algorithm called self‐organizing map with a relational perspective map (SOM‐RPM) for visualizing and analyzing complex PEEM‐generated datasets. The application of SOM‐RPM is demonstrated using synchrotron‐based X‐ray magnetic circular dichroism (XMCD)‐PEEM data acquired from a pyrrhotite sample. Traditional visualization approaches for XMCD‐PEEM data may not fully capture the complexity of the sample, especially in the case of heterogeneous materials. By applying SOM‐RPM to the XMCD‐PEEM data, a colored topographic map is created that represents the spectral similarities and dissimilarities among the pixels. This approach allows for a more intuitive and easily interpretable representation of the data without the need of data binning or spectral smoothing. The results of the SOM‐RPM analysis are compared to the conventional visualization approach, highlighting the advantages of SOM‐RPM in revealing features that are not readily observable in the conventional method. This study suggests that the SOM‐RPM approach can be used complimentarily for other PEEM‐based measurements, such as core level and valence band X‐ray photoelectron spectroscopy.
Environmental Radiation Impact on Lifetimes and Quasiparticle Tunneling Rates of Fixed-Frequency Transmon Qubits
Creators: name: Gordon, R. T.
name: Murray, C. E.
name: Kurter, C.
name: Sandberg, M.
name: Hall, S. A.
name: Balakrishnan, K.
name: Shelby, R.
name: Wacaser, B.
name: Stabile, A. A.
name: Sleight, J. W.
name: Brink, M.
name: Rothwell, M. B.
name: Rodbell, K.
name: Dial, O.
name: Steffen, M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum computing relies on the operation of qubits in an environment as free of noise as possible. This work reports on measuring the impact of environmental radiation on lifetimes of fixed frequency transmon qubits with various capacitor pad geometries by varying the amount of shielding used in the measurement space. It was found that the qubit lifetimes are robust against these shielding changes until the most extreme limit was tested without a mixing chamber shield in the refrigerator. In contrast, the quasiparticle tunneling rates were found to be extremely sensitive to all configurations tested, indicating these devices are not yet limited by losses related to superconducting quasiparticles.
description: 6 pages, 7 figures, and 2 tables
Early Effects of Environment: A Comparison of Prenatal Care in South Africa and the United States
Creators: name: Piper, Allison
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Prenatal development has a critical impact on a child’s life and is strongly affected by environmental factors, especially quality of prenatal care and home environment. Data was gathered in a South African village and a United States city through interviews, photojournalism, and archival data. A total of 14 women (10 South African, 4 American) were interviewed about their prenatal care and pregnancy experiences, and 12 were photographed in their surrounding environment. The photographs serve as a visual and emotional complement to the paper. The project showed that the extended family in South Africa provides a strong social support system for pregnant women, which serves to mitigate much of the lack of resources in the environment. In the United States, prenatal care typically assumes much of the education and social monitoring role, due to the smaller role of the American extended family and the cultural value placed on biomedical care. While the two environments are different, mothers and newborns in both environments generally have the necessary prenatal support.
Geographic heterogeneity in the prevalence of human papillomavirus in head and neck cancer
Creators: name: Tajara, E.H.
name: Moyses, R.A.
name: Toporcov, T.N.
name: Levi, J.E.
name: Boccia, S.
name: Beachler, D.C.
name: Olshan, A.F.
name: Wunsch-Filho, V.
name: Brennan, P.
name: D'Souza, G.
name: Renard, H.
name: Chopard, P.
name: McKay-Chopin, S.
name: Gheit, T.
name: Wisniewski, K.
name: Rindi, G.
name: Merletti, F.
name: Cadoni, G.
name: Ahrens, W.
name: Conway, D.I.
name: Abedi-Ardekani, B.
name: Anantharaman, D.
name: Scelo, G.
name: Tommasino, M.
name: Wright, S.
name: Carreira, C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Human papillomavirus (HPV) causes oropharyngeal squamous cell carcinoma (OPSCC), although strongly divergent results have been reported regarding the prevalence of HPV16 in different countries, whether this represents important differences in etiology remains unclear. Applying rigorous protocols for sample processing, we centrally evaluated 1,420 head and neck tumors (533 oropharynx, 395 oral cavity and 482 larynx) from studies conducted in the US, Europe and Brazil for mucosal HPV DNA and p16INK4a expression to evaluate regional heterogeneity in the proportion of HPV16-associated OPSCC and other head and neck cancer, and to assess covariates associated with the risk of HPV16-positive OPSCC. While majority of OPSCC in the US (60%) were HPV16-positive, this proportion was 31% in Europe and only 4% in Brazil (p < 0.01). Similar differences were observed for other head and neck tumors, ranging from 7% in the US and 5% in Europe, to 0% in South America. The odds of HPV16-positive OPSCC declined with increasing pack years of smoking (OR: 0.75; 95% CI: 0.64–0.87) and drink years of alcohol use (OR: 0.64; 95% CI: 0.54–0.76). These results suggest that while the contribution of HPV16 is substantial for the oropharynx, it remains limited for oral cavity and laryngeal cancers.
Spatial Inhomogeneity In Solar Faculae
Creators: name: Elek, A.
name: Gyenge, N.
name: Korsós, M B.
name: Erdélyi, R.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: In this paper, we investigate the inhomogeneous spatial distribution of solar faculae. The focus is on the latitudinal and longitudinal distributions of these highly localised features covering ubiquitously the solar surface. The statistical analysis is based on white light observations of the Solar and Heliospheric Observatory (SOHO) and Solar Dynamics Observatory (SDO) between 1996 and 2014. We found that the fine structure of the latitudinal distribution of faculae displays a quasi-biennial oscillatory pattern. Furthermore, the longitudinal distribution of photospheric solar faculae does not show homogeneous behaviour either. In particular, the non-axisymmetric behaviour of these events show similar properties as that of the active longitude (AL) found in the distribution of sunspots. Our results, preliminary though, may provide a valuable observational constrain for developing the next-generation solar dynamo model.
Standard Model CP-violation and Baryon asymmetry
Creators: name: Gavela, M. B.
name: Hernández, P.
name: Orloff, J.
name: Pène, O.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Simply based on CP arguments, we argue against a Standard Model explanation of the baryon asymmetry of the universe in the presence of a first order phase transition. A CP-asymmetry is found in the reflection coefficients of quarks hitting the phase boundary created during the electroweak transition. The problem is analyzed both in an academic zero temperature case and in the realistic finite temperature one. The building blocks are similar in both cases: Kobayashi-Maskawa CP-violation, CP-even phases in the reflection coefficients of quarks, and physical transitions due to fermion self-energies. In both cases an effect is present at order $α_W^2$ in rate. A standard GIM behaviour is found as intuitively expected. In the finite temperature case, a crucial role is played by the damping rate of quasi-particles in a hot plasma, which is a relevant scale together with $M_W$ and the temperature. The effect is many orders of magnitude below what observation requires, and indicates that non standard physics is indeed needed in the cosmological scenario.
description: 15p, LaTeX (3figs incl.), CERN 93/7081,LPTHE Orsay-93/48,HUTP-93/A036,HD-THEP-93-45
Additional file 1 of Comparing options for females seeking permanent contraception in high resource countries: a systematic review
Creators: name: Gormley, Rebecca
name: Vickers, Brian
name: Cheng, Brooke
name: Norman, Wendy V.
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1: PRISMA-2009-Checklist
Fermion masses and neutrino mixing in an U(1)_H flavor symmetry model with hierarchical radiative generation for light charged fermion masses
Creators: name: Hernandez-Galeana, Albino
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: I report the analysis performed on fermion masses and mixing, including neutrino mixing, within the context of a model with hierarchical radiative mass generation mechanism for light charged fermions, mediated by exotic scalar particles at one and two loops, respectively, meanwhile the neutrinos get Majorana mass terms at tree level through the Yukawa couplings with two SU(2)_L Higgs triplets. All the resulting mass matrices in the model, for the u, d, and e fermion charged sectors, the neutrinos and the exotic scalar particles, are diagonalized in exact analytical form. Quantitative analysis shows that this model is successful to accommodate the hierarchical spectrum of masses and mixing in the quark sector as well as the charged lepton masses. The lepton mixing matrix, V_{PMNS}, is written completely in terms of the neutrino masses m_1, m_2, and m_3. Large lepton mixing for θ_{12} and θ_{23} is predicted in the range of values 0.7 \lesssim \sin^22θ_{12}\lesssim 0.7772 and 0.87 \lesssim \sin^22θ_{23} \lesssim 0.9023 by using 0.033 \lesssim s_{13}^2 \lesssim 0.04. These values for lepton mixing are consistent with 3 σallowed ranges provided by recent global analysis of neutrino data oscillation. From Δm_{\text{sol}}^2 bounds, neutrino masses are predicted in the range of values m_1 \thickapprox (1.706 - 2.494) x 10^{- 3} eV, m_2 \thickapprox (6.675 - 12.56) x 10^{- 3} eV, and m_3 \thickapprox (1.215 - 2.188) x 10^{- 2} eV, respectively. The above allowed lepton mixing leads to the quak-lepton complementary relations θ_{12}^{CKM} + θ_{12}^{PMNS} \thickapprox 41.543^{\circ} - 44.066^{\circ} and θ_{23}^{CKM}+θ_{23}^{PMNS}\thickapprox 36.835^{\circ} - 38.295^{\circ}.
description: 36 pages, LaTeX, 7 eps figures; typos corrected, references added, version to appear in Physical Review D
Dreams Deferred: Capital Punishment and Injustice in Texas
Creators: name: Jay, Janet
Publisher: name: Carnegie Mellon University
Year: 2007
Subjects: History

description: There has been a great deal of academic scholarship about the effectiveness of capital punishment in deterring violent crime. While the rest of the Western world has been attempting to enforce nonexecution as a human rights issue, the policy of the national government in the United States has shifted to the toleration of capital punishment by the states, and a series of capital crimes have been added by the federal Congress for the limited jurisdiction of the federal government.