Hydrogen Peroxide Quantification Using Zero Dimensional Carbon Nanostructured Materials: A Review
Creators: name: Sharma, Priti
name: Nangare, Sopan N.
name: Bagade, Shashikant B.
name: Sonawane, Sandeep S.
name: Patil, Dipak D.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Space Science
Medicine
Molecular Biology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Computational Biology

description: Hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) is suspected to promote cancer. Higher concentrations of H<sub>2</sub>O<sub>2</sub> have always harmed mammalian cells, other living things, as well as the environment. As well, elevated concentrations of H<sub>2</sub>O<sub>2</sub> might cause major health problems such as cancer, cardiovascular disease, asthma, Alzheimer’s disease, etc. As all, bioanalysis, environmental protection, and food security are needed for the rapid and accurate sensing of H<sub>2</sub>O<sub>2</sub>. For the sensing of H<sub>2</sub>O<sub>2</sub>, nanoparticle construction of carbon-based sensors has been used. Zero-dimensional (0D) nanostructures or nanosized designs of carbon-based fluorescent probes such as graphene quantum dots (GQDs) and carbon quantum dots (CQDs/CDs) are gaining popularity in sensing. Therefore, this review focused on current developments in sensing systems made possible by innovative applications of GQDs with CQDs, with a focus on how these materials significantly enhance overall H<sub>2</sub>O<sub>2</sub> detection. In brief, the review article focuses on the basic insights of H<sub>2</sub>O<sub>2</sub> and carbon-based nanomaterials. After this, the use of GQDs and CQDs-based sensors for H<sub>2</sub>O<sub>2</sub> detection is discussed in a brief period from 2015 to 2024. At last, the current challenges, future prospects, and concluding remarks have been added. As an outcome, GQDs and CQDs showed the potential for sensing H<sub>2</sub>O<sub>2</sub> because of their distinctive electrical, fluorescent, photoluminescent, chemiluminescent, and electrochemiluminescent features. Carbon-based sensors for the recognition of H<sub>2</sub>O<sub>2</sub> utilized a variety of methods, counting PET, IFF, static quenching, dynamic quenching, FRET, etc. As an outcome, it appears that carbon-based nanoscale sensors offered potential options for highly effective yet precise sensors for the detection of H<sub>2</sub>O<sub>2</sub>. In winding up, the GQDs and CQDs-based sensing nanosystems provide a new platform for the recognition of H<sub>2</sub>O<sub>2</sub> that can open an innovative era for the diagnosis of health issues as well as monitor several environmental processes and issues at the point of care. H<sub>2</sub>O<sub>2</sub> detection is crucial due to its carcinogenic and oxidative stress effects. Nanostructured carbon materials are promising for H<sub>2</sub>O<sub>2</sub> quantification. Quantum dots (carbon and graphene) provided a high sensitivity for H<sub>2</sub>O<sub>2</sub> detection. Detection mechanisms for H<sub>2</sub>O<sub>2</sub> include quenching, oxidation, ECL-RET, IFE, electron transfer, etc.