cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Characterization of Aberrant DNA Methylation Changes in Fertility and Paragangliomas
Creators: name: Pflüger, Jahnvi
Publisher: name: University of Utah
Year: 2019

description: Our work focussed on how germ cell DNA is packaged and if it is poised by distinctive chromatin to influence embryo development. Finally, is misregulation of that poising a common theme observed in infertility and cancer? We profiled the epigenome in mature human sperm and found that packaging in mature sperm revealed the presence of two programs - a future program, involved in guiding embryo development and a past program, involved in spermatogenesis (Chapter 2). Next, the clearest place a chromatin problem can manifest is in infertility. We asked if the DNA methylation status of seven imprinted regions can serve as a diagnostic to inform two groups of infertile patients about the risk of their offspring developing a disorder. Although our results did not provide a causal link for the trans-generational inheritance of DNA methylation defects leading to imprinting disease, it showed a strong correlation between infertility in males and aberrations of DNA methylation at select imprinted loci (Chapter 3). Taken together, our data suggests that germ cell chromatin plays a significant role in early embryonic development and infertility. Finally, we investigated how defects in a metabolic enzyme, succinate dehydrogenase (SDH) can have an impact on chromatin packaging and transcriptome of paragangliomas. We also queried the epigenetic status of paragangliomas lacking mutations in SDH. We compared our two PGL subclasses to a progenitor cell type, neural crest cells (NCCs). Strikingly, we found that both subclasses of PGLs are phenotypically very similar. Furthermore, they share the majority of regions that gain and lose DNA methylation compared to neural crest cells. Whole exome sequencing of both PGL subclasses shows iv mutations in many epigenetic modifier genes and hence we speculate that in PGLs lacking SDH mutations, epigenetic enzymes may harbor mutations that could phenocopy the misregulation in SDH deficient tumors (Chapter 4). Together, we hope that by querying the epigenetic status in a normal system and comparing these findings to perturbed systems, we have gained more insight into the role of epigenetic misregulation in infertility and cancer.
F-Theory Duals of Nonperturbative Heterotic E8xE8 Vacua in Six Dimensions
Creators: name: Candelas, Philip
name: Perevalov, Eugene
name: Rajesh, Govindan
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a systematic way of generating F-theory models dual to nonperturbative vacua (i.e., vacua with extra tensor multiplets) of heterotic E8xE8 strings compactified on K3, using hypersurfaces in toric varieties. In all cases, the Calabi-Yau is an elliptic fibration over a blow up of the Hirzebruch surface F_n. We find that in most cases the fan of the base of the elliptic fibration is visible in the dual polyhedron of the Calabi-Yau, and that the extra tensor multiplets are represented as points corresponding to the blow-ups of the F_n.
description: 24 pages, LaTex, no figures. Significant errors corrected, leading to a modification of some of our conclusions. References added
MOESM1 of Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study
Creators: name: Galmes-Panades, Aina
name: Varela-Mato, Veronica
name: Konieczna, Jadwiga
name: Wärnberg, Julia
name: Martínez-González, Miguel
name: Salas-Salvadó, Jordi
name: Corella, Dolores
name: Schröder, Helmut
name: Vioque, Jesús
name: Alonso-Gómez, Ángel
name: Martínez, J.
name: Serra-Majem, Luís
name: Estruch, Ramon
name: Tinahones, Francisco
name: Lapetra, José
name: Pintó, Xavier
name: Tur, Josep
name: Garcia-Rios, Antonio
name: Riquelme-Gallego, Blanca
name: Gaforio, José
name: Matía-Martín, Pilar
name: Daimiel, Lidia
name: Micó Pérez, Rafael Manuel
name: Vidal, Josep
name: Vázquez, Clotilde
name: Ros, Emilio
name: Garcia-Arellano, Ana
name: Díaz-López, Andrés
name: Asensio, Eva
name: Castañer, Olga
name: Fiol, Francisca
name: Mira-Castejón, Luis
name: Moreno Rodríguez, Anai
name: Benavente- Marín, Juan
name: Abete, Itziar
name: Tomaino, Laura
name: Casas, Rosa
name: Barón López, F.
name: Fernández-García, José
name: Santos-Lozano, José
name: Galera, Ana
name: Mascaró, Catalina
name: Razquin, Cristina
name: Papandreou, Christopher
name: Portoles, Olga
name: Pérez-Vega, Karla
name: Fiol, Miguel
name: Compañ-Gabucio, Laura
name: Vaquero-Luna, Jessica
name: Ruiz-Canela, Miguel
name: Becerra-Tomás, Nerea
name: Fitó, Montserrat
name: Romaguera, Dora
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Computational Biology

description: Additional file 1: Table S1. Associations of total inactive time with adiposity indicators and cardio-metabolic risk factors (with further adjustment for light physical activity, instead of moderate-to-vigorous physical activity). Table S2. Associations of total inactive time with adiposity indicators and cardio-metabolic risk factors (with further adjustment for light physical activity, instead of moderate-to-vigorous physical activity and waist circumference as an indicator of adiposity). Table S3. Prevalence ratio of metabolic syndrome parameters according to tertiles of sedentary time (with further adjustment for light physical activity, instead of moderate-to-vigorous physical activity). Table S4. Isotemporal substitution of inactive time (30 min/day) with sleep time and physical activity on cardio-metabolic risk.
Fast forward of adiabatic control of tunneling states
Creators: name: Nakamura, Katsuhiro
name: Khujakulov, Anvar
name: Avazbaev, Sanat
name: Masuda, Shumpei
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: By developing the preceding work on the fast forward of transient phenomena of quantum tunneling by Khujakulov and Nakamura (Phys. Rev. {\bf A 93}, 022101 (2016) ), we propose a scheme of the exact fast forward of adiabatic control of stationary tunneling states with use of the electromagnetic field. The idea allows the acceleration of both the amplitude and phase of wave functions throughout the fast-forward time range. The scheme realizes the fast-forward observation of the transport coefficients under the adiabatically-changing barrier with the fixed energy of an incoming particle. As typical examples we choose systems with (1) Eckart's potential with tunable asymmetry and (2) double $δ$-function barriers under tunable relative height. We elucidate the driving electric field to guarantee the stationary tunneling state during a rapid change of the barrier and evaluate both the electric-field-induced temporary deviation of transport coefficients from their stationary values and the modulation of the phase of complex scattering coefficients
description: 15 pages, 8 figures
Observation of Time-Dependent CP Violation in B0 -> eta' K0 Decays and Improved Measurements of CP Asymmetries in B0 -> phiK0, KsKsKs and B0 -> J/psi K0 Decays
Creators: name: The Belle Collaboration
name: Chen, K. -F.
Publisher: name: arXiv
Year: 2006
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present improved measurements of CP-violation parameters in B0->phiK0, eta'K0, KsKsKs decays based on a sample of 535x10^6 BBbar pairs collected at the Y(4S) resonance with the Belle detector at the KEKB energy-asymmetric e+e- collider. We obtain sin2phi_1^eff=+0.64+-0.10(stat)+-0.04(syst) for B0->eta'K0, +0.50+-0.21(stat)+-0.06(syst) for B0->phiK0, and +0.30+-0.32(stat) +-0.08(syst) for B0->KsKsKs decays. We have observed CP violation in the B0->eta'K0 decay with a significance of 5.6 standard deviations. We also perform an improved measurement of CP asymmetries in B0->J/psiK0 decays and obtain sin2phi_1=+0.642+- 0.031(stat)+-0.017(syst).
description: 6 pages, 3 figures, updated to be consistent with the version published in PRL
Changing Agricultural Suitability: Model Development and Applications in the Past and Future
Creators: name: Bidez, Clarice Lee
Publisher: name: University of Utah
Year: 2019
Subjects: Physical geography
Geography
Agriculture

description: Modeling the relationships between climate and crop growth is an important tool to study agriculture in the past and future. Agricultural suitability models, which estimate the probability of rain-fed cultivation in a particular location, provide an opportunity to predict agricultural conditions for multiple scenarios in space and time. This thesis presents a methodological approach to developing a simple agricultural suitability model with machine learning techniques and applying it to two scenarios. First, to predict the potential impacts of climate change, the model was used to project agricultural suitability at the end of the 21st century at the global scale. Second, the model was used to predict agricultural suitability in Range Creek Canyon, an important archeological site in east-central Utah, in the 10th -13th centuries. The agricultural suitability model was supplemented with a streamflow model of Range Creek to address the potential for irrigation. The predictive power of random forest and XGBoost were compared and random forest was found to build the stronger model in this application. Applied to the future, this model predicts a net increase of 13.8-28.2% of agriculturally suitable land by AD 2100. The broad patterns agree with past suitability models, with the largest gains of suitability distributed in the high-northern latitudes. Decreases in suitability are projected in some regions, particularly in the current most intensely cultivated regions including Midwestern America. A sensitivity analysis revealed that the main driver of these shifts was changing growing season length and intensity, while changing soil moisture had a limited effect. Applied to the past in Range Creek Canyon, the model predicted very low agricultural suitability, providing evidence that rain-fed agriculture in Range Creek Canyon from AD 900-1200 was nearly impossible. Modeled Range Creek streamflow predicted that mean streamflow from AD 900-1200 was 6.34% greater than modern streamflow. The area of maize fields that could be irrigated with this amount of streamflow was approximately 30.6 hectares. The agricultural suitability model applied to two scenarios differing in scales of time and space demonstrate how it can provide meaningful insights to a broad range of past and future scenarios.
Early-time Spitzer observations of the type II-Plateau supernova, 2004dj
Creators: name: Kotak, Rubina
name: Meikle, Peter
name: van Dyk, Schuyler
name: Hoeflich, Peter
name: Mattila, Seppo
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present mid-infrared observations with the Spitzer Space Telescope of the nearby type II-P supernova, SN 2004dj, at epochs of 89 to 129 days. We have obtained the first mid-IR spectra of any supernova apart from SN 1987A. A prominent [NiII] 6.64 micron line is observed, from which we deduce that the mass of stable nickel must be at least 2.2e10(-4) Msun. We also observe the red wing of the CO-fundamental band. We relate our findings to possible progenitors and favour an evolved star, most likely a red supergiant, with a probable initial mass between ~10 and 15 Msun.
description: ApJ Letters (accepted)
Characteristics and Optimal Combination Pharmacotherapy for Newly-Treated Patients with Diabetic Painful Neuropathy
Creators: name: Kuo, Kuan-Ling
Publisher: name: University of Utah
Year: 2019

description: To compare patient characteristics and healthcare costs between newly-treated DPN patients receiving mono-pharmacotherapy and those receiving combination pharmacotherapy. A patient cohort was identified diagnosed with DPN during 2006-2013 in Inovalon's MORE2® registry, a healthcare data warehouse with national medical/pharmacy claims, continuously enrolled for at least 18 months. Patients were included if they were ≥18 years at the time of their first DPN prescription for a tricyclic antidepressant (TCA), opioid, duloxetine, gabapentin, pregabalin, or any route lidocaine. They were classified as having mono- or combination pharmacotherapy (time between the first and second medicine was within 30 days). If there was a 60-day prescription fill gap, the prescription was classified as discontinued. Switch or add-on groups were categorized based on continuation of the index medicine. A simple proportional hazards model was conducted for comparing time to discontinue, switch, or add on. Multiple logistic regression was used for identifying predictors of combination pharmacotherapy. There were 7,145 patients on mono-pharmacotherapy and 421 patients on combination pharmacotherapy. The top three index medicines were gabapentin (55.7%), opioids (13.1%), and pregabalin (12.9%) in the mono-pharmacotherapy group, and opioids+gabapentin (27.1%), TCAs+gabapentin (17.6%), and duloxetine+gabapentin (8.6%) in the combination group. Patients on combination pharmacotherapy were 130% iv more likely to discontinue their medications than patients on mono-pharmacotherapy. There was no statistically significant difference in time to switch (p=0.254) and add on (p=0.069) between mono- and combination pharmacotherapy. Patients who were female, with >7 co-morbidities, and who had depression or arthritis were more likely to start with combination pharmacotherapy. Patients who were older than 65 and those with hypertension were less likely to start with combination pharmacotherapy. The total post- minus pre-index cost had no statistically significant difference between mono- and combination pharmacotherapy (p=0.66). Newly-treated DPN patients should add on another medication sooner than 30 days when considering combination pharmacotherapy. Because all first-line medications have similar efficacy, the cost should be considered in the treatment decision. For this reason, gabapentin and TCAs are recommended. If considering the pre-index costs, taking combination pharmacotherapy will not cost more money; the policy maker can reimburse either gabapentin+opioid or TCA+gabapentin.
Insight into High-order Harmonic Generation from Solids: The Contributions of the Bloch Wave-packets Moving on the Group and Phase Velocities
Creators: name: Du, Tao-Yuan
name: Huang, Xiao-Huan
name: Bian, Xue-Bin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We study numerically the Bloch electron wavepacket dynamics in periodic potentials to simulate laser-solid interactions. We introduce a new perspective in the coordinate space combined with the motion of the Bloch electron wavepackets moving at group and phase velocities under the laser fields. This model interprets the origins of the two contributions (intra- and interband transitions) of the high-order harmonic generation (HHG) by investigating the local and global behavior of the wavepackets. It also elucidates the underlying physical picture of the HHG intensity enhancement by means of carrier-envelope phase (CEP), chirp and inhomogeneous fields. It provides a deep insight into the emission of high-order harmonics from solids. This model is instructive for experimental measurements and provides a new avenue to distinguish mechanisms of the HHG from solids in diffrent laser fields.
Caseworker Factors That Influence Removal Decisions in Child Welfare Investigations
Creators: name: Vanderloo, Mindy J.
Publisher: name: University of Utah
Year: 2019
Subjects: Social work
Individual & family studies

description: Child welfare agencies across the United States investigate millions of allegations of child maltreatment, including abuse and neglect, every year. Approximately 15% of the youth involved in these investigations are removed from their homes. Removals are tremendously impactful and change the trajectory of the lives of children and their families for better or worse. Despite the extreme importance of the decision to remove children from their homes, these decisions are not always made systematically. Decisions are known to vary between workers-beyond variance attributable to the presence of child and family risk factors. There is limited information on what influences this variance. This study explored whether caseworker factors influence removal decisions using real-world data. Caseworker factors explored included demographics, experience, attitudes toward child safety and family preservation, and childhood history of adverse events. The results from this study suggested caseworkers with more experience, male caseworkers, and caseworkers with more ACEs are less likely to remove children from their homes. Each of these are potential areas that could be targeted by policy or practice interventions to reduce inconsistencies in removal decisions. The findings from this study contribute to the growing body of empirical research on CPS decision making, furthering knowledge that can inform theory and child welfare practice.
On Isomorphisms of Grassmann Spaces
Creators: name: Havlicek, Hans
Publisher: name: arXiv
Year: 2012
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 51A10

description: We exhibit isomorphisms of Grassmann spaces and their relationship with collineations and embeddings of the underlying projective spaces.
description: Character encoding problem resolved, no changes otherwise
On free stable distributions
Creators: name: Hasebe, Takahiro
name: Kuznetsov, Alexey
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 46L54, 60E07

description: We investigate analytical properties of free stable distributions and discover many connections with their classical counterparts. Our main result is an explicit formula for the Mellin transform, which leads to explicit series representations for the characteristic function and for the density of a free stable distribution. All of these formulas bear close resemblance to the corresponding expressions for classical stable distributions. As further applications of our results, we give an alternative proof of the duality law due to Biane and a new factorization of a classical stable random variable into an independent (in the classical sense) product of a free stable random variable and a power of a Gamma(2) random variable.
description: 12 pages, final version of the preprint
Cell Surface Engineering and Its Applications in Cancer Therapy
Creators: name: Lee, Daniel Yongwon
Publisher: name: University of Utah
Year: 2019
Subjects: Cellular biology
Biomedical engineering
Pharmaceutical sciences

description: Remodeling of cell surface to install new features has continuously attracted attention for cell therapy. This dissertation focuses on a method of cell surface engineering using bioactive molecules to transiently award distinct functions to ordinary cells. Spontaneous incorporation of lipid-conjugated biomaterials to the cell membrane through hydrophobic interaction provides the basis for noninvasive cell surface modification. First, mesenchymal stem cells (MSCs) were surface-engineered to embed a recombinant protein, stromal-derived factor 1 (SDF-1), for an enhanced target-specific homing effect. The SDF-1-embedded MSCs showed augmented migration towards the concentration gradient of their molecular target, CXC chemokine receptor 4 (CXCR4). Next, Jurkat cells were surface-engineered with magnetic resonance imaging (MRI) contrast agents to demonstrate the suitability of surface engineering in cell tracking. The contrast agent-embedded Jurkat cells were detectable by MRI. To demonstrate the applicability of this technology in translational research, immune effector cells were surface-engineered with antibody-drug conjugates (ADCs) and their combined efficacy was examined in animal tumor models. This combination of chemotherapy and immunotherapy showed significant efficacy in treating cancers; however, the immunomodulatory effects of chemotherapy were difficult to control. This observation was due to the off-target toxicity of chemotherapy that damages the host immune cells: many cancer patients often require replenishment of immune cells after a series of chemotherapy in order to benefit from immunotherapy. In order to overcome the challenge, new chemoimmunotherapeutic strategies require sufficient immunomodulatory ability of chemotherapy, targeted chemotherapy for reduced toxicity, and enhanced recruitment of immune cells to the tumor tissue. Surface engineering to affix chemotherapeutic agents on the cell membrane of immune effector cells is therefore an attractive approach. In the main study of this dissertation, natural killer 92 (NK92) cells were surface-engineered to carry ADCs on their membranes. A lipid-conjugated model ADC, trastuzumab-DM1 (T-DM1), homogeneously modified the allogeneic NK92 cells without affecting the viability of NK92 cells. T-DM1-embedded NK92 (SE-NK/T-DM1) cells exerted strong anti-cancer activity through targeted chemoimmunotherapy. Although a wide range of experimental observations has proven that the SE-NK/T-DM1 cells are effective over the co-treatment of T-DM1 and NK92 cells, further investigations should be conducted to validate their potential for clinical application.
Additional file 2: of Associations of physical activity with childhood asthma, a population study based on the WHO - health behaviour in school-aged children survey
Creators: name: Lochte, Lene
name: Petersen, Poul
name: Nielsen, Kim
name: Andersen, Anette
name: Platts-Mills, Thomas
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Correlation matrix. Presents correlations for asthma variables. (DOCX 23 kb)
Characterizing Background Seismicity in the Region Surrounding Milford, Utah
Creators: name: Potter, Stephen Austin
Publisher: name: University of Utah
Year: 2019
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Geophysics

description: A proposed site for the Department of Energy's Frontier Observatory for Research in Geothermal Energy (FORGE) is located in southwestern Utah, in the Milford Basin, west of the Mineral Mountains. This site is at the intersection of the Intermountain Seismic Belt and the Pahranagat Shear Zone. This area is known for geothermal energy and the Roosevelt Hot Springs power plant, east of FORGE, has been active since 1984. For FORGE to be successful, an induced seismicity mitigation plan is required. There have been 185 seismic events from 1850 to 2016 cataloged by the University of Utah Seismograph Stations (UUSS) in this area. In this study, I completed a noise analysis on the local seismometers IMU, NMU, and DWU and determined the capabilities for the seismic detection work. To lower the magnitude of completeness, subspace detection analysis was applied for the years 2010-2016 and the best events were relocated in a relative sense together with events from the UUSS catalog. The relocated events were analyzed through principal component analysis to determine their hypocentral geometric distribution. Within the study area, we determined a new potential fault just north of Milford, Utah and observed hypocentral geometries in the Mineral Mountains that are consistent with previously reported tectonic structures. Finally, with the additions to the UUSS catalog and completed work, we were able to complete a stability analysis to show that we successfully reduced the magnitude of completeness for the area during the time period of 2010-2016. These results have allowed a seismicity baseline to be established for the induced seismicity mitigation plan for FORGE.
PSR J1119-6127 and its pulsar wind nebula following the magnetar-like bursts
Creators: name: Blumer, Harsha
name: Safi-Harb, Samar
name: McLaughlin, Maura A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present a Chandra Director's Discretionary Time observation of PSR J1119-6127 and its compact X-ray pulsar wind nebula (PWN) obtained on 27 October 2016, three months after the Fermi and Swift detection of millisecond bursts in hard X-rays, accompanied by >160 times increase in flux. This magnetar-like activity, the first observed from a rotation-powered radio pulsar, provides an important probe of the physical processes that differentiate radio pulsars from magnetars. The post-burst X-ray spectrum of the pulsar can be described by a single powerlaw model with a photon index of 2.0\pm0.2 and an unabsorbed flux of 5.7e-12 ergs/cm^2/s in the 0.5-7.0 keV energy range. At the time of Chandra observations, the pulsar was still brighter by a factor of ~22 in comparison with its quiescence. The X-ray images reveal a nebula brighter than in the pre-burst Chandra observations (from 2002 and 2004), with an unabsorbed flux of 2.2e-13 ergs/cm^-2/s. This implies a current X-ray efficiency of ~0.001 at a distance of 8.4 kpc. In addition, a faint torus-like structure is visible along the southeast-northwest direction and a jet-like feature perpendicular to the torus towards the southwest. The PWN is best fitted by an absorbed powerlaw with a photon index of 2.2\pm0.5 (post-burst). While the pulsar can still be energetically powered by rotation, the observed changes in PSR~J1119-6127 and its PWN following the magnetar-like bursts point to an additional source of energy powered by its high-magnetic field.
description: Accepted for publication in ApJL
The Career Paths of Female Nurses: Decisions Associated with Intention to Leave Direct Patient Care
Creators: name: Hofmann, Linda Carol
Publisher: name: University of Utah
Year: 2019
Subjects: subject: Nursing
subject: FOS: Health sciences

description: This study was designed in two sequential phases; 1) to describe the career paths of experienced nurses related to the intention to leave direct patient care and decisions associated with changing or advancing their education, and 2) to explore how pregnancy, childbirth, and mothering young children impact the lives of nurses working in direct patient care. A multimethod qualitative design with two qualitative components, QUAL1 → QUAL2, was utilized. Study participants were female nurses educated in the United States and licensed in Utah from 6 to 12 years. The QUAL1 core component consisted of unstructured interviews (n = 39), the results of which were used to form the QUAL2 sequential component of semistructured interviews (n = 45). Findings from QUAL1 revealed that mothering responsibilities and family obligations strongly influenced nurses with regard to career decisions and educational advancement. Organizational impacts such as lack of employer appreciation and inflexible scheduling/lack of control over the schedule by the nurse led to a "tipping point" for nurses, and to thoughts of intention to leave and ultimately resignation from their position. The second phase of the study focused on the nurse when pregnant and working in direct patient care and/or while having young children at home. Results revealed that there are distinct physical and emotional challenges and hardships experienced by female nurses. There were few accommodations in workload for pregnancy, and few supports, and major challenges regarding breastfeeding. Financial necessity, and the satisfaction derived from working in patient care, kept nurses working at the bedside.
Supergravity Coupled to Chiral and Yang-Mills Matter at One Loop
Creators: name: Gaillard, Mary K.
name: Jain, Vidyut
name: Saririan, Kamran
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present the full result for the divergent one-loop contribution to the effective boson Lagrangian for supergravity coupled to chiral and Yang-Mills supermultiplets. We also consider the specific case of dilaton couplings in effective supergravity Lagrangians from superstrings, for which the one-loop result is considerably simplified.
description: 14 pages
Challenges in Quantitative Cardiovascular Magnetic Resonance Perfusion
Creators: name: Likhite, Devavrat
Publisher: name: University of Utah
Year: 2019
Subjects: Computer Engineering
Biomedical engineering
Electrical engineering

description: Medical imaging has evolved in leaps and bounds during the last century. Several medical imaging modalities such as X-rays, single photon emission computer tomography (SPECT), positron emission tomography (PET), computer tomography (CT), magnetic resonance imaging (MRI) have been developed. However, MRI has a distinct advantage over most of these imaging techniques. MRI does not use ionizing radiation, and hence, is considered a safer option for noninvasive imaging. However, every imaging modality comes with its set of limitations and challenges. Although quantitative myocardial perfusion MRI has been studied by researchers over a few decades, it has still not developed into a clinical tool. There is no consensus on the choice of imaging protocol to be used. The scientific community is still divided on the choice of pharmacokinetic model to be used for quantification of myocardial perfusion. In this dissertation, novel techniques were developed and implemented to address a few of the challenges faced by fully quantitative myocardial perfusion MRI. We strive to make it simpler and more accurate. It is with the development of such easy-to-use techniques that cardiac perfusion MRI will find increasing clinical use. These developments are a step in the transition of quantitative myocardial perfusion MRI from an "evolving tool" to an "evolved and matured tool."
title: ADCO, Grènetier de Cîteaux : comptes (1499-1503) (11 H 1173), f. 00632
Creators: name: de la Côte-d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173), f. 00632, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Additional file 1 of MicroRNA-320d regulates tumor growth and invasion by promoting FoxM1 and predicts poor outcome in gastric cardiac adenocarcinoma
Creators: name: Chen, Xiaojie
name: Gao, Shegan
name: Zhao, Zhiwei
name: Liang, Gaofeng
name: Kong, Jinyu
name: Feng, Xiaoshan
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Virology

description: Additional file 1: Figure S1. Efficiency of lentivirus transfection into GCA cell lines. OE-19 cells were transfected lentivirus with GFP, while SK-GT2 cells were transfected with e-cherry. At 48 h post-transfection, cells were fluorescently imaged by microscope. Compared with bright field images and fluorescence images, it could conclude that GFP-transfected OE-19 cells were more than 90%, and e-cherry-transfected SK-GT2 cells was more than 90%, which showed high efficacy of lentivirus transfection. Figure S2. Effect of miR-320d on cell invasion ability in SK-GT2 cell. Wound healing assay was performed to demonstrate the cell invasion ability after down-regulation of miR-320d in SK-GT2 cell. (A) Representative bright-field microscope images of SK-GT2 cell showing wound healing status after down-regulation of miR-320d at 0 and 24 h. (B) Quantification of SK-GT2 cell invasion ability rates after down-regulation of miR-320d. The NS represents that there is no significant difference between these two groups. Figure S3. RT-qPCR quantification of FoxM1 mRNA in EV-transfected SK-GT2 tumors and 320d-inhibitor-transfected SK-GT2 tumors. Nude mice were subcutaneously injected with 1x106 EV-transfected SK-GT2 cells or 1 × 106 320d-inhibitor-transfected SK-GT2 cells. After 4 weeks later, the tumors were harvested for FoxM1 mRNA quantification. The FoxM1 mRNA level was increased in 320d-inhibitor transfected SK-GT2 tumor. The * represents significant difference from miR-320d inhibitor-transfected tumors to EV-transfected tumors (***: P  < 0.001). Figure S4. Immunohistochemical (IHC) analysis of FoxM1 protein expression in xenografted OE-19 tumors or SK-GT2 tumors. (A) IHC staining of FoxM1 antibody in xenografted tumor. Upregulation or downregulation of miRNA-320d can reduce or increase the expression level of FoxM1 protein in xenografted tumors. (B) The IHC scores of FoxM1 protein level in each group. The * represents significant difference from miR-320d vector-transfected tumors to EV-transfected tumors (**: P  < 0.01). Table S1. Primers for FoxM1 and GAPDH Gene Sequence. Table S2. Primers for FoxM1 3′-UTR (MT) clone and FoxM1 3′-UTR (WT) clone. Table S3. Group Settings for dual luciferase reporter assays (n = 5)
Floquet Many-body Engineering: Topological and Many-body Physics in Phase Space Lattices
Creators: name: Liang, Pengfei
name: Marthaler, Michael
name: Guo, Lingzhen
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Other Condensed Matter (cond-mat.other)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Hamiltonians which are inaccessible in static systems can be engineered in periodically driven many-body systems, i.e., Floquet many-body systems. We propose to use interacting particles in a one-dimensional (1D) harmonic potential with periodic kicking to investigate two-dimensional (2D) topological and many-body physics. Depending on the driving parameters, the Floquet Hamiltonian of single kicked harmonic oscillator has various lattice structures in phase space. The noncommutative geometry of phase space gives rise to the topology of the system. We investigate the effective interactions of particles in phase space and find that the point-like contact interaction in quasi-1D real space becomes a long-rang Coulomb-like interaction in phase space, while the hardcore interaction in pure-1D real space becomes a confinement quark-like potential in phase space. We also find that the Floquet exchange interaction does not disappear even in the classical limit, and can be viewed as an effective long-range spin-spin interaction induced by collision. Our proposal may provide platforms to explore new physics and exotic phases by \textit{Floquet many-body engineering}.
description: More references are added in the 2nd version
Matrix methods for radial Schrödinger eigenproblems defined on a semi-infinite domain
Creators: name: Aceto, Lidia
name: Magherini, Cecilia
name: Weinmüller, Ewa B.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: In this paper, we discuss numerical approximation of the eigenvalues of the one-dimensional radial Schrödinger equation posed on a semi-infinite interval. The original problem is first transformed to one defined on a finite domain by applying suitable change of the independent variable. The eigenvalue problem for the resulting differential operator is then approximated by a generalized algebraic eigenvalue problem arising after discretization of the analytical problem by the matrix method based on high order finite difference schemes. Numerical experiments illustrate the performance of the approach.
Additional file 1: of Associations of physical activity with childhood asthma, a population study based on the WHO - health behaviour in school-aged children survey
Creators: name: Lochte, Lene
name: Petersen, Poul
name: Nielsen, Kim
name: Andersen, Anette
name: Platts-Mills, Thomas
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Univariate analyses. Presents univariate analyses for PA, covariates, Ever Asthma (Tables 15, 16); PA, covariates, Current Asthma (Tables 151, 161); covariates, PA (Table 17). (PDF 133 kb)
LMC Blue Supergiant Stars and the Calibration of the Flux-weighted Gravity--Luminosity Relationship
Creators: name: Urbaneja, M. A.
name: Kudritzki, R. P.
name: Gieren, W.
name: Pietrzynski, G.
name: Bresolin, F.
name: Przybilla, N.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: High quality spectra of 90 blue supergiant stars in the Large Magellanic Cloud are analyzed with respect to effective temperature, gravity, metallicity, reddening, extinction and extinction law. An average metallicity, based on Fe and Mg abundances, relative to the Sun of [Z] = -0.35 +/- 0.09 dex is obtained. The reddening distribution peaks at E(B-V) = 0.08 mag, but significantly larger values are also encountered. A wide distribution of the ratio of extinction to reddening is found ranging from Rv = 2 to 6. The results are used to investigate the blue supergiant relationship between flux-weighted gravity, and absolute bolometric magnitude. The existence of a tight relationship, the FGLR, is confirmed. However, in contrast to previous work the observations reveal that the FGLR is divided into two parts with a different slope. For flux-weighted gravities larger than 1.30 dex the slope is similar as found in previous work, but the relationship becomes significantly steeper for smaller values of the flux-weighted gravity. A new calibration of the FGLR for extragalactic distance determinations is provided.
description: Accepted for publication by AJ
Photon Echoes Produced by Switching Electric Fields
Creators: name: Alexander, A. L.
name: Longdell, J. J.
name: Sellars, M. J.
name: Manson, N. B.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We demonstrate photon echoes in Eu$^{3+}$:Y$_{2}$SiO$_{5}$ by controlling the inhomogeneous broadening of the Eu$^{3+}$ $^{7}$F$_{0}\leftrightarrow^{5}$D$_{0}$ optical transition. This transition has a linear Stark shift and we induce inhomogeneous broadening by applying an external electric field gradient. After optical excitation, reversing the polarity of the field rephases the ensemble, resulting in a photon echo. This is the first demonstration of such a photon echo and its application as a quantum memory is discussed.
description: improved introduction, including theoretical outline of the relvant quantum memory proposal
Critical behavior of the two-dimensional icosahedron model
Creators: name: Ueda, Hiroshi
name: Okunishi, Kouichi
name: Krčmár, Roman
name: Gendiar, Andrej
name: Yunoki, Seiji
name: Nishino, Tomotoshi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: In the context of a discrete analogue of the classical Heisenberg model, we investigate critical behavior of the icosahedron model, where the interaction energy is defined as the inner product of neighboring vector spins of unit length pointing to vertices of the icosahedron. Effective correlation length and magnetization of the model are calculated by means of the corner-transfer matrix renormalization group (CTMRG) method. Scaling analysis with respect to the cutoff dimension $m$ in CTMRG reveals the second-order phase transition characterized by the exponents $ν= 1.62\pm0.02$ and $β= 0.12\pm0.01$. We also extract the central charge from the classical analogue of the entanglement entropy as $c = 1.90\pm0.02$, which cannot be explained by the minimal series of conformal field theory.
description: 6 pages, 5 figures
Grain Evolution across the Shocks in the L1448-mm Outflow
Creators: name: Jimenez-Serra, I.
name: Martin-Pintado, J.
name: Rodriguez-Franco, A.
name: Martin, S.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The recent detection of shock-precursors toward the very young L1448-mm outflow offers us the possibility to study the grain chemistry during the first stages of the shock evolution, constraining the molecules ejected from grains and the species formed in gas phase. Observations of key molecules in the grain chemistry such as SiO, CH3OH, SO, CS, H2S, OCS, and SO2 toward this outflow are presented. The line profiles and the derived abundances show three distinct velocity regimes that trace the shock evolution: the preshock, the shock-precursor and the postshock gas. The SiO, CH3OH, SO, and CS abundances are enhanced with respect to the quiescent gas by 1 order of magnitude in the shock-precursor component, and by 3 orders of magnitude in the postshock gas. The derived SiO and CH3OH abundances are consistent with the recent ejection of these molecules from grains. Since H2S is only enhanced in the shock-precursor component, and OCS and SO2 are undetected, SO and CS are the most abundant sulfur-bearing species in the grain mantles of L1448-mm. The ejection of mainly SO and CS rather than H2S or OCS from grains, suggests that the sulfur chemistry will depend on the chemical "history" of the grain mantles in outflows and hot cores.
description: 4 pages, 2 figures, accepted for publication in ApJL
A unified matrix approach to the representation of Appell polynomials
Creators: name: Aceto, Lidia
name: Malonek, Helmuth R.
name: Tomaz, Graça
Publisher: name: arXiv
Year: 2014
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 15A16, 65F60, 11B83

description: In this paper we propose a unified approach to matrix representations of different types of Appell polynomials. This approach is based on the creation matrix - a special matrix which has only the natural numbers as entries and is closely related to the well known Pascal matrix. By this means we stress the arithmetical origins of Appell polynomials. The approach also allows to derive, in a simplified way, the properties of Appell polynomials by using only matrix operations.
Additional file 4 of Gene S-phase kinase associated protein 2 is a novel prognostic marker in human neoplasms
Creators: name: Li, Guo-Sheng
name: Huang, Tao
name: Zhou, Hua-Fu
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 4. The SKP2 expression trends at protein levels in multiple neoplasms
Additional file 1: of Migration and tuberculosis transmission in a middle-income country: a cross-sectional study in a central area of São Paulo, Brazil
Creators: name: Pescarini, Julia
name: Simonsen, Vera
name: Lucilaine Ferrazoli
name: Rodrigues, Laura
name: Oliveira, Rosangela
name: Waldman, Eliseu
name: Houben, Rein
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplement Table S1 describe the cases of TB among Brazilians and South American migrants in the study area. Some differences regarding demographic characteristics and TB risk factors for TB transmission were less pronounced in the study area compared to the study group, suggesting oversampling of retreatments, PLHIV and drug users among Brazilians. (DOCX 17 kb)
Learning Fashion Compatibility with Bidirectional LSTMs
Creators: name: Han, Xintong
name: Wu, Zuxuan
name: Jiang, Yu-Gang
name: Davis, Larry S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: The ubiquity of online fashion shopping demands effective recommendation services for customers. In this paper, we study two types of fashion recommendation: (i) suggesting an item that matches existing components in a set to form a stylish outfit (a collection of fashion items), and (ii) generating an outfit with multimodal (images/text) specifications from a user. To this end, we propose to jointly learn a visual-semantic embedding and the compatibility relationships among fashion items in an end-to-end fashion. More specifically, we consider a fashion outfit to be a sequence (usually from top to bottom and then accessories) and each item in the outfit as a time step. Given the fashion items in an outfit, we train a bidirectional LSTM (Bi-LSTM) model to sequentially predict the next item conditioned on previous ones to learn their compatibility relationships. Further, we learn a visual-semantic space by regressing image features to their semantic representations aiming to inject attribute and category information as a regularization for training the LSTM. The trained network can not only perform the aforementioned recommendations effectively but also predict the compatibility of a given outfit. We conduct extensive experiments on our newly collected Polyvore dataset, and the results provide strong qualitative and quantitative evidence that our framework outperforms alternative methods.
description: ACM MM 17