cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Degenerative parkinsonian syndromes: what the neuropathologist can tell the clinician
Creators: name: Horvath, Judit
Publisher: name: Université de Genève
Year: 2014
Subjects: info:eu-repo/classification/ddc/616.8
Parkinson's disease
Neuropathologie
Alzheimer's disease

description: The definitive diagnosis of Parkinson's disease, and indeed, of most neurodegenerative diseases, is based on the postmortem examination. Neuropathology continues to be the authoritative approach until reliable clinical and biological markers are found, as well as it helps to understand how clinical symptoms, imaging, and biological findings correlate with the topography, the type and the severity of the lesions. In this thesis, I review the neuropathological characteristics and clinicopathological correlations in Parkinson's disease and other related disorders, also including the particularities of genetically determined conditions. I explain how the continued stream of novel molecular genetic and neuropathological data on neurodegenerative disorders makes the relationship between phenotype, genotype and pathology more and more complex. I address the clinical relevance and the challenges of mixed neurodegenerative pathologies in elderly patients. I present our review paper on Lewy body disorders. I demonstrate the clinicopathological confrontation in an unusual case of corticobasal degeneration. I present our large autopsy study on the etiologies and diagnostic accuracy of parkinsonism as well as the neuropathological findings in a cohort of patients with Parkinson's disease related dementia. Finally, I report on our work on the neuropathological correlates of parkinsonian symptoms in pure Alzheimer's disease. My future plans include the organization of a brain donation program for patients with neurodegenerative disorders. A cohort of prospectively followed patients with subsequent postmortem examination and brain banking would be an ideal setting for clinicopathological correlations, for validation of diverse biomarkers, and for basic research purposes.
Analysis and monitoring of anti-HLA antibodies in solid-organ and stem cell transplantation : What to do? When should they be tested?
Creators: name: Ferrari-Lacraz, Sylvie
Publisher: name: Université de Genève
Year: 2015
Subjects: info:eu-repo/classification/ddc/616
Transplantation
HLA
Anticorps
AntiHLA
Analyses médicales

description: Due to the shortage of deceased donor the search for suitable kidney from living donors has intensified. Unfortunately, recipient-donor couples are often HLA-mismatched due to the high polymorphism of HLA loci. Nowadays patients often need more than one transplant during their lifetime and are at major risk factor for developing anti-HLA antibodies. To deal with this problem, we increased the number of tests and their sensitivity, and by carrying out accurate HLA-typing to ensure more appropriate organ allocation and the efficient follow-up and treatment of recipients. We increased our catalogue of assays and developed guidelines for physicians regarding the acceptance of organs and an adequate follow-up of their patients. With strategies such as living-donor, ABO-incompatible kidney transplantation and compatible non-directed donor exchange, we have so far obtained 100% graft survival for all types of living-donor kidney transplantation, as well as an excellent survival rate for pancreas and islet grafts.
Polyethylene glycol supported phosphorus chloride: An efficient and recyclable catalyst for the preparation of nitriles from aldoximes
Creators: name: Zhang, Xiao-Lan
name: Shou-Ri Sheng
name: Wei, Mei-Hong
name: Liu, Xiao-Ling
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Polyethylene glycol (PEG) supported phosphorus chloride has been developed and used as an efficient and recyclable catalyst for dehydration of various aldoximes into the corresponding nitriles. This protocol has many advantages such as high conversion, high selectivity, short reaction time, mild reaction conditions, and simple experimental procedure.
Additional file 5: of Intraspecific variation of residual heterozygosity and its utility for quantitative genetic studies in maize
Creators: name: Liu, Nannan
name: Liu, Jianxiao
name: Li, Wenqiang
name: Pan, Qingchun
name: Liu, Jie
name: Yang, Xiaohong
name: Yan, Jianbing
name: Xiao, Yingjie
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Figure S4. Simulation and enrichment analysis. (PDF 215Â kb)
Additional file 6: of Intraspecific variation of residual heterozygosity and its utility for quantitative genetic studies in maize
Creators: name: Liu, Nannan
name: Liu, Jianxiao
name: Li, Wenqiang
name: Pan, Qingchun
name: Liu, Jie
name: Yang, Xiaohong
name: Yan, Jianbing
name: Xiao, Yingjie
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Figure S5. Relationship between residual heterozygosity and recombinant rates. (PDF 294Â kb)
Additional file 1: of GWAS implicated risk variants in different genes contribute additively to increase the risk of coronary artery disease (CAD) in the Pakistani subjects
Creators: name: Shahid, Saleem
name: Shabana, N.
name: Rehman, Abdul
name: Humphries, Steve
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Computational Biology

description: Table S1. Basic feature of the SNPs. (DOCX 14 kb)
Additional file 1: of Strategies for high-altitude adaptation revealed from high-quality draft genome of non-violacein producing Janthinobacterium lividum ERGS5:01
Creators: name: Kumar, Rakshak
name: Acharya, Vishal
name: Singh, Dharam
name: Kumar, Sanjay
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Figure S1. Multilocus sequence analysis (MLSA) clustering based phylogenetic tree of six concatenated housekeeping genes as derived from the whole genome sequence from the strains of Janthinobacterium. The tree was constructed using the neighbor-joining method based on the JTT matrix-based model using MEGA7 .Bootstrap values over 50% (1000 replications) were shown at each node. All positions containing gaps and missing data were eliminated. The clustering patterns are in agreement with the data generated by the maximum likelihood method. (PDF 238Â kb)
Additional file 2: of Strategies for high-altitude adaptation revealed from high-quality draft genome of non-violacein producing Janthinobacterium lividum ERGS5:01
Creators: name: Kumar, Rakshak
name: Acharya, Vishal
name: Singh, Dharam
name: Kumar, Sanjay
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Table S1. Whole genome sequence-based in silico comparison of strain ERGS5:01 and other related Janthinobacterium strains in database for DDH and ANI. (DOCX 17Â kb)
Additional file 3: of Strategies for high-altitude adaptation revealed from high-quality draft genome of non-violacein producing Janthinobacterium lividum ERGS5:01
Creators: name: Kumar, Rakshak
name: Acharya, Vishal
name: Singh, Dharam
name: Kumar, Sanjay
Publisher: name: figshare
Year: 2018
Subjects: subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Figure S2. Certificate of deposition of strainERGS5:01 at Microbial Culture Collection (MCC) at National Centre for Cell Science, Pune, India. (PDF 377Â kb)
Motor abnormalities among children with PANS and/or PANDAS
Creators: name: Unsbo, Erika
Publisher: name: figshare
Year: 2017
Subjects: subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine

description: Introduction: Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) and Pediatric Autoimmune Neuropsychiatric disorders Associated with Streptococcal Infections (PANDAS) are putative diagnoses with symptoms including tics and obsessive compulsive disorder. These disorders are believed to be caused by antibodies against the basal ganglia. Some reports show that these patients have affected motor control. This may be explained by the hypothesis that antibodies against the basal ganglia cause the disorders. Aims: This study aimed to compare the presence of motor abnormalities among patients with PANS and/or PANDAS and age- and sex-matched healthy persons. Material and Methods: 17 persons aged 8-19 years that had been diagnosed with PANS and/or PANDAS in Sweden were included in the study. 25 controls were matched with the patients regarded age and sex. Both groups were then examined with 6 tests of motor function. The tests were scored and groups were compared using linear regression. The total score for the test was 0-22 where 0 points indicated a test performed without any impairments and 22 points was a test performed with large difficulty. Results: The mean score for the patients was 8.2 points and the mean score for the controls was 4.5 points, indicating a higher presence of motor abnormalities among patients with PANS and/or PANDAS. The effect adjusted for age was 3.7 points lower for the controls compared to the patients, p = 0.0004. Conclusions: Our results suggest that patients with PANS and/or PANDAS have more motor abnormalities compared to age and sex matched controls.
Additional file 4: of Strategies for high-altitude adaptation revealed from high-quality draft genome of non-violacein producing Janthinobacterium lividum ERGS5:01
Creators: name: Kumar, Rakshak
name: Acharya, Vishal
name: Singh, Dharam
name: Kumar, Sanjay
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Table S2. Genes predicted to encode industrially important enzymes in the genome of J. lividum ERGS5:01. (DOCX 14Â kb)
Additional file 5: of Strategies for high-altitude adaptation revealed from high-quality draft genome of non-violacein producing Janthinobacterium lividum ERGS5:01
Creators: name: Kumar, Rakshak
name: Acharya, Vishal
name: Singh, Dharam
name: Kumar, Sanjay
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology
subject: Computational Biology

description: Figure S3. Pan genome analysis of genus Janthinobacterium. The pan-genome profile plot displaying the total and the core gene families for each genome with a curve fit exponent of 0.43. [Number of unique genes observed for strains are displayed in brackets; 1. J. lividum ERGS5:01 (236); 2. J. sp. 551a (0); 3. J. agaricidamnosum DSM 9628 (1412); 4.J. sp. CG23_2 (2860); 5. J. sp. CG3(1038); 6. J. sp. HH01 (1764) 7.J. sp. KBS0711 (66) 8. J. lividum H-24 (217); 9. J. lividum NFR18 (86); 10. J. sp. Marseille (1625); 11. J. lividumMTR (197) 12.J. sp. OK676 (171); 13.J. lividum PAMC25724 (152); 14. J. psychotolerans S3–2 (644); 15.J. sp. RA13 (170); 16. J. lividum RIT308 (75); 17.J. sp. 344 (11); 18.J. sp. Ant5–2-1 (136); 19.J. sp. HH100 (15); 20.J. sp. HH102 (72); 21.J. sp._HH103 (16); 22.J. sp. HH104 (114); 23.J. sp. HH106 (100); 24.J. sp. HH107 (78); 25.J. sp. MP5059B (136); 26.J. sp. TND4EL3 (504); 27.J. sp. YR213 (92)]. (PDF 85 kb)
Additional file 6: of Strategies for high-altitude adaptation revealed from high-quality draft genome of non-violacein producing Janthinobacterium lividum ERGS5:01
Creators: name: Kumar, Rakshak
name: Acharya, Vishal
name: Singh, Dharam
name: Kumar, Sanjay
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Table S3. List of genes encoding proteins associated with cold adaptation from strain ERGS5:01 among the 1066 core genomes of 27 strain within genus Janthinobacterium (DOCX 14Â kb)
Additional file 7: of Strategies for high-altitude adaptation revealed from high-quality draft genome of non-violacein producing Janthinobacterium lividum ERGS5:01
Creators: name: Kumar, Rakshak
name: Acharya, Vishal
name: Singh, Dharam
name: Kumar, Sanjay
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Table S4. List of genes among the core genomes of 27 Janthinobacterium strains associated with general COG functional categories (DOCX 14Â kb)
A REVIEW ON BIOLOGICAL ACTIVITIES OF COMMON MALLOW (MALVA SYLVESTRIS L.)
Creators: name: Paul, Dipak
Publisher: name: figshare
Year: 2017
Subjects: subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Botany
subject: Biotechnology
subject: Microbiology

description: Paul D. A REVIEW ON BIOLOGICAL ACTIVITIES OF COMMON MALLOW (MALVA SYLVESTRIS L.). 2016;4(5):1-5
Additional file 1: of Identification of residue pairing in interacting β-strands from a predicted residue contact map
Creators: name: Mao, Wenzhi
name: Wang, Tong
name: Zhang, Wenxuan
name: Gong, Haipeng
Publisher: name: figshare
Year: 2018
Subjects: Biochemistry
Medicine
Molecular Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Computational Biology

description: Text S1. Technical details of the γ-normalized scale method for ridge detection; Table S1. List of domains in the training set; Table S2. Results of structure prediction for 61 mainly β proteins. (PDF 537 kb)
Additional file 1: of Relationship of sarcopenia with steatohepatitis and advanced liver fibrosis in non-alcoholic fatty liver disease: a meta-analysis
Creators: name: Yu, Rui
name: Shi, Qiangwei
name: Liu, Lei
name: Chen, Lidong
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Table S1. Methodological quality of included studies assessed using a method based in the 9-star Newcastle-Ottawa Scale. (DOCX 26 kb)
Additional file 10: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Autonomous rSaTar-MULE1 (ArS-MULE1) element sequences in the rice (Japonica) genome. (PDF 140Â kb)
Additional file 11: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: Computational Biology

description: Alignment of rSaTar element conserved on Chromosome 1 of rice Japonica and Indica. (PDF 89Â kb)
Additional file 12: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Sample relative rSaTar insertions in Chromosome 1 of Oryza sativa Japonica and Indica. (PDF 45Â kb)
Invasive hemodynamic assessment of pulmonary hypertension
Creators: name: Pagnamenta, Alberto
Publisher: name: Université de Genève
Year: 2015
Subjects: info:eu-repo/classification/ddc/616
Pulmonary hypertension
Right heart catheterization
Swan-Ganz

description: The diagnosis of pulmonary hypertension requires an invasive confirmation of an elevated mean pulmonary artery pressure during a right heart catheterization. The present thesis reviews the invasive hemodynamic approaches to assess the functional state of the pulmonary circulation and its impact on right ventricular function in pulmonary vascular diseases. Pulmonary vascular resistance is better characterized by multi-point pressure/flow measurements. The occlusion analysis of the pulmonary artery pressure decay curve permits to locate the site of increased resistance. Pulmonary vascular resistance permits to assess the steady component of the pulmonary circulation, whereas the pulsatile component can be better appreciated by pulmonary vascular impedance. Determination of ventriculo-arterial coupling permits to assess the impact of an elevated afterload on right ventricular function, which ultimately determines symptoms and prognosis of patients with pulmonary hypertension.
Additional file 1: of Dietary patterns, BCMO1 polymorphisms, and primary lung cancer risk in a Han Chinese population: a case-control study in Southeast China
Creators: name: He, Fei
name: Xiao, Ren-dong
name: Lin, Tao
name: Xiong, Wei-min
name: Xu, Qiu-ping
name: Li, Xu
name: Liu, Zhi-qiang
name: He, Bao-chang
name: Hu, Zhi-jian
name: Cai, Lin
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Biological Sciences not elsewhere classified
Developmental Biology

description: Table S1. All rotated factor loadings (multiplied by 100) for the 4 factors from principal components analysis of all line items from the food-frequency questionnaire. (DOCX 17Â kb)
Continental gabbros in the Dent Blanche Tectonic System (Western Alps): from the pre-Alpine crustal structure of the Adriatic palaeomargin to the geometry of an alleged subduction interface
Creators: name: Manzotti, Paola
name: Ballèvre, Michel
name: Piaz, Giorgio Vittorio Dal
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Deformation–mineral growth relationships and Alpine mineral analyses of the Berrio Gabbro basic and ultrabasic rocks
Le rôle et l'impact des médecins dans la prévention du tabagisme : Quand la pratique clinique rencontre la santé publique…
Creators: name: Humair, Jean-Paul
Publisher: name: Université de Genève
Year: 2015
Subjects: info:eu-repo/classification/ddc/613

description: Les médecins peuvent aider leurs patients fumeurs avec des conseils et traitements pharmacologiques efficaces. Cependant, les médecins ne conseillent qu'un tiers des fumeurs avec peu de stratégies efficaces. Une formation interactive augmente la qualité des conseils médicaux et l'arrêt du tabac des patients avec un bon rapport coût-efficacité. Une législation interdisant de fumer dans les lieux publics protège la population des effets nocifs du tabagisme passif et amène des bénéfices pour la santé, notamment une réduction des hospitalisations pour exacerbation aiguë de BPCO. Une interdiction totale de fumer dans un hôpital diminue le tabagisme passif et favorise l'arrêt du tabac des employés et patients fumeurs. Une formation systématique et interactive, l'organisation de la pratique et le remboursement des prestations améliore l'aide médicale à l'arrêt du tabac. La recherche doit évaluer l'effet des aides à l'arrêt du tabac par internet ou téléphone portable et des mesures pour respecter l'interdiction de fumer.
Motoriska avvikelser hos barn med PANS och/eller PANDAS
Creators: name: Unsbo, Erika
Publisher: name: figshare
Year: 2017
Subjects: subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine

description: Motoriska avvikelse hos barn med PANS och/eller PANDAS.
Additional file 13: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Architecture and distribution of sorghum sSaTar elements. (PDF 56Â kb)
Additional file 2: of Dietary patterns, BCMO1 polymorphisms, and primary lung cancer risk in a Han Chinese population: a case-control study in Southeast China
Creators: name: He, Fei
name: Xiao, Ren-dong
name: Lin, Tao
name: Xiong, Wei-min
name: Xu, Qiu-ping
name: Li, Xu
name: Liu, Zhi-qiang
name: He, Bao-chang
name: Hu, Zhi-jian
name: Cai, Lin
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Table S2. Baseline characteristics by quartile (Q) of factor scores. (DOCX 33Â kb)
Additional file 14: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology

description: sSatar cluster on sorghum Chromosome 1. (PDF 46Â kb)
Additional file 15: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Architecture and distribution of citrus cSaTar elements. (PDF 59Â kb)
Additional file 16: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Sample cSaTar clusters on Citrus. (PDF 35Â kb)
Additional file 17: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: PCR amplification of genomic regions containing gSaTar clusters. (PDF 268Â kb)
Additional file 1: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Virology

description: gSaTar terminal inverted repeat sequences. (PDF 55Â kb)
Additional file 2: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Computational Biology

description: gSaTar elements on the 16Â Mb artificial assembly (1% of guayule genome). (PDF 41Â kb)
Additional file 3: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Virology

description: gSaTar clusters in the guayule CLC Genomics Workbench assembly. (PDF 46Â kb)
Additional file 4: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Virology
subject: Computational Biology

description: Autonomous gSaTar-MULE1 (AgS-MULE1) and cluster with non-autonomous gSaTar elements in the guayule CLC Genomics Workbench assembly. (PDF 47Â kb)
Obesity-related complications in children
Creators: name: Maggio, Albane Bertha
Publisher: name: Université de Genève
Year: 2016
Subjects: info:eu-repo/classification/ddc/618
Childhood obesity
Complications
Physical activity

description: The epidemic of obesity concerns 17% of Swiss children. This chronic condition leads to many complications that can already be seen during early childhood. It is therefore of primordial importance to detect them as soon as possible, as they are, in turn, followed with high morbidity and mortality in adults. We could demonstrate in our cohort study that almost 90% of the overweight and obese children were suffering of at least one medical complication, with already 30% of them presenting at least one cardiovascular risk factor. Other conditions shouldn't be underestimated as they impact the quality of life, the mental health as well as the treatment success rate. Through our research, we assessed the prevalence of the majority of those complications and studied the influence of physical activity on cardiovascular and metabolic health of our patients, as it is also a key point in the obesity treatment strategy.
Additional file 5: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Virology
subject: Computational Biology

description: Alignment of non-autonomous gSaTar and autonomous gSaTar-MULE (AgS-MULE) terminal inverted repeat domains. (PDF 69Â kb)
Gaming: from Addiction Mechanisms to Clinical Practices
Creators: name: Thorens, Gabriel
Publisher: name: Université de Genève
Year: 2016
Subjects: info:eu-repo/classification/ddc/616.89
Video game
Addiction
Gaming
Game
Mmorpg

description: Video game addiction is the main theme of this thesis. After a brief definition of addiction, the focus is on the specific addictive properties of Internet and games. Massively multiplayer online role-playing games (MMORPGs) are described, as they tend to be the most addictive type of game, with a specific focus on World of Warcraft (WoW). Issues of diagnostic criteria for Internet addiction and Internet gaming disorder (IGD) are be presented.
Educating recently immigrated students: Exploring the suitability of scientific Modules in secondary education
Creators: name: Schmiedebach, Mario
name: Litzke, Vivienne
name: Wegner, Claas
Publisher: name: CERN
Year: 2020
Subjects: recently immigrated students, science education, integration, modules

description: Background: Over the last few years there has been a surge in the number of recently immigrated students to Germany. Schools often educate these students in separate language learning classes to facilitate integration, as immediate integration can be perceived as frustrating, boring and associated with language-use anxiety. Purpose: Using short-term science modules as an intervention method can possibly circumvent several negative emotions such as frustration, boredom, and language-use anxiety, as well as encourage scientific interest. Sample/setting: Students enrolled in nine preparation classes at seven different secondary schools in Germany (N=137, mean age = 13.9 years) participated in a module lasting three to four days. Design and methods: To provide a range of topics, three modules in zoology, botany and electricity were offered. Each module could be chosen by each participating school and taught using the content and language learning (CLIL) concept combined with an action-oriented approach. A pre-post-design surveyed student perspectives with questionnaires before and after the module. Results: After the module, we observed a significant decrease in boredom and language-use anxiety in the regular class, and a comparable trend was seen in frustration and perceived language barriers. However, we saw a significant increase in scientific interest. Conclusions/Implications for classroom practice and future research: Content learning should be used in language preparation classes to ease the integration process for recently immigrated students. In particular, modules provide the opportunity for students to experience both the subject-specific content and language level necessary to participate in regular classes. These modules are easy to implement, as schools do not have to reorganize their preparation classes. Future research should examine differences in language level and knowledge gain, as well as add positive constructs such as “joy” to better grasp how international student perceive their regular classes. Keywords: recently immigrated students, science education, modules
description: Progress in Science Education (PriSE), Vol 2, No 1 (2019)
“Deep endometriosis with colorectal involvement: a standardization proposal from diagnosis to surgical procedure”
Creators: name: Wenger, Jean-Marie
Publisher: name: Université de Genève
Year: 2016
Subjects: info:eu-repo/classification/ddc/618
Deep infiltrating endometriosis-colorectal involvement-standardization-clinic-diagnosis-surgical treatment

description: Deep infiltrating endometriosis with colorectal involvement is a complex and challenging disease characterized by a long delay in diagnosis, debated preoperative work-up, and controversial and difficult surgical treatment. The literature is inconsistent regarding disease definition, clinical research criteria, and outcomes, which leads to inconclusive scientific debate characterized by misconceptions. Clinical consequences result from delayed diagnosis or misdiagnosis, unnecessary investigations, and incomplete and inadequate treatments that lead to psychological and physical sequelae for patients. The aim of this work was to review the literature to propose standardization for the clinical and instrumental diagnosis and surgical treatment of deep infiltrating endometriosis with bowel implants.
Additional file 6: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Plant Biology

description: Classification of rice rSaTar elements. (PDF 44Â kb)
Additional file 7: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: The rSaTar2/Micron terminal inverted repeats are similar to those defining the ArS-MULE2 autonomous Mu-like transposon. (PDF 83Â kb)
Supplementary data and original records from Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells
Creators: name: Emfinger, Christopher H.
name: Welscher, Alecia
name: Zihan Yan
name: Yixi Wang
name: Conway, Hannah
name: Moss, Jennifer B.
name: Moss, Larry G.
name: Remedi, Maria S.
name: Nichols, Colin G.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology

description: ATP-sensitive potassium channels (KATP channels) are critical nutrient sensors in many mammalian tissues. In the pancreas, KATP channels are essential for coupling glucose metabolism to insulin secretion. While orthologous genes for many components of metabolism–secretion coupling in mammals are present in lower vertebrates, their expression, functionality and ultimate impact on body glucose homeostasis are unclear. In this paper, we demonstrate that zebrafish islet β-cells express functional KATP channels of similar subunit composition, structure and metabolic sensitivity to their mammalian counterparts. We further show that pharmacological activation of native zebrafish KATP using diazoxide, a specific KATP channel opener, is sufficient to disturb glucose tolerance in adult zebrafish. That β-cell KATP channel expression and function are conserved between zebrafish and mammals illustrates the evolutionary conservation of islet metabolic sensing from fish to humans, and lends relevance to the use of zebrafish to model islet glucose sensing and diseases of membrane excitability such as neonatal diabetes.
Supplementary Figures from Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells
Creators: name: Emfinger, Christopher H.
name: Welscher, Alecia
name: Zihan Yan
name: Yixi Wang
name: Conway, Hannah
name: Moss, Jennifer B.
name: Moss, Larry G.
name: Remedi, Maria S.
name: Nichols, Colin G.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology

description: ATP-sensitive potassium channels (KATP channels) are critical nutrient sensors in many mammalian tissues. In the pancreas, KATP channels are essential for coupling glucose metabolism to insulin secretion. While orthologous genes for many components of metabolism–secretion coupling in mammals are present in lower vertebrates, their expression, functionality and ultimate impact on body glucose homeostasis are unclear. In this paper, we demonstrate that zebrafish islet β-cells express functional KATP channels of similar subunit composition, structure and metabolic sensitivity to their mammalian counterparts. We further show that pharmacological activation of native zebrafish KATP using diazoxide, a specific KATP channel opener, is sufficient to disturb glucose tolerance in adult zebrafish. That β-cell KATP channel expression and function are conserved between zebrafish and mammals illustrates the evolutionary conservation of islet metabolic sensing from fish to humans, and lends relevance to the use of zebrafish to model islet glucose sensing and diseases of membrane excitability such as neonatal diabetes.
Supplementary Information from Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus
Creators: name: Dolan, Stephen K.
name: Bock, Tobias
name: Hering, Vanessa
name: Owens, Rebecca A.
name: Jones, Gary W.
name: Blankenfeldt, Wulf
name: Doyle, Sean
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Structural Biology

description: Supplementary Information (Data and Supplementary methods)
Additional file 8: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Plant Biology

description: Sample rSaTar clusters on the rice genome Oryza sativa V7_JGI. (PDF 45Â kb)
title: Species-specific sensitivity of different bee species after a field-realistic application of an insecticide
Creators: name: Jütte, Tobias
name: Wernecke, Anna
name: Klaus, Felix
name: Pistorius, Jens
name: Dietzsch, Anke
Publisher: name: Bundesbehörden und Einrichtungen im Geschäftsbereich des Bundesministeriums für Ernährung und Landwirtschaft (BMEL)
Year: 2025
Subjects: subject: 630

description: Julius-Kühn-Archiv, vol. 481Hazards of pesticides to bees, 16th International Symposium of the ICP-PR Bee Protection Group, - Proceedings -; 15th - 17th October, 2024; Sevilla (Spain), p. 109
Additional file 9: of Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes
Creators: name: Valdes Franco, JosĂŠ
name: Wang, Yi
name: Huo, Naxin
name: Ponciano, Grisel
name: Colvin, Howard
name: McMahan, Colleen
name: Gu, Yong
name: Belknap, William
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Computational Biology

description: Autonomous rSaTar-Mules in the rice genome. (PDF 46Â kb)
MOESM2 of Engineering global transcription to tune lipophilic properties in Yarrowia lipolytica
Creators: name: Wang, Man
name: Liu, Guan-Nan
name: Liu, Hong
name: Zhang, Lu
name: Li, Bing-Zhi
name: Li, Xia
name: Liu, Duo
name: Yuan, Ying-Jin
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 2. Supporting Online Texts.
File S1. Supplemental methods: Protein Interaction Reporter (PIR) crosslinking from Protein interaction networks at the host–microbe interface in Diaphorina citri, the insect vector of the citrus greening pathogen
Creators: name: J. S. Ramsey
name: J. D. Chavez
name: R. Johnson
name: S. Hosseinzadeh
name: J. Mahoney
name: J. Mohr
name: F. Robison
name: X. Zhong
name: D. G. Hall
name: M. MacCoss
name: J. Bruce
name: M. Cilia
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biochemistry
subject: Immunology
subject: FOS: Clinical medicine
subject: 60114 Systems Biology
subject: FOS: Biological sciences

description: The Asian citrus psyllid (Diaphorina citri) is the insect vector responsible for the worldwide spread of ‘Candidatus Liberibacter asiaticus’ (CLas), the bacterial pathogen associated with citrus greening disease. Developmental changes in the insect vector impact pathogen transmission, such that D. citri transmission of CLas is more efficient when bacteria are acquired by nymphs when compared with adults. We hypothesize that expression changes in the D. citri immune system and commensal microbiota occur during development and regulate vector competency. In support of this hypothesis, more proteins, with greater fold changes, were differentially expressed in response to CLas in adults when compared with nymphs, including insect proteins involved in bacterial adhesion and immunity. Compared with nymphs, adult insects had a higher titre of CLas and the bacterial endosymbionts Wolbachia, Profftella and Carsonella. All Wolbachia and Profftella proteins differentially expressed between nymphs and adults are upregulated in adults, while most differentially expressed Carsonella proteins are upregulated in nymphs. Discovery of protein interaction networks has broad applicability to the study of host–microbe relationships. Using protein interaction reporter technology, a D. citri haemocyanin protein highly upregulated in response to CLas was found to physically interact with the CLas coenzyme A (CoA) biosynthesis enzyme phosphopantothenoylcysteine synthetase/decarboxylase. CLas pantothenate kinase, which catalyses the rate-limiting step of CoA biosynthesis, was found to interact with a D. citri myosin protein. Two Carsonella enzymes involved in histidine and tryptophan biosynthesis were found to physically interact with D. citri proteins. These co-evolved protein interaction networks at the host–microbe interface are highly specific targets for controlling the insect vector responsible for the spread of citrus greening.
Suplemental material from Historical amphibian declines and extinctions in Brazil linked to chytridiomycosis
Creators: name: Tamilie Carvalho
name: C. Guilherme Becker
name: Toledo, Luís Felipe
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: List of collections; Tables S1-S6; Figures S1-S3
MOESM3 of Engineering global transcription to tune lipophilic properties in Yarrowia lipolytica
Creators: name: Wang, Man
name: Liu, Guan-Nan
name: Liu, Hong
name: Zhang, Lu
name: Li, Bing-Zhi
name: Li, Xia
name: Liu, Duo
name: Yuan, Ying-Jin
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 3: Table S1. Oligonucleotide primers used for Q-PCR. Table S2. Primers for PCR amplification to identify the genotypes of mutants.Â Table S3. Primers for PCR amplification to identify the genotypes of mutants and the insertion site. Table S4. Up-regulated genes in the pathways of ketone bodies and alpha-linolenic acid metabolism in Yl_5_2. Table S5. Down-regulated genes in the pathway of fatty acid biosynthesis in Yl_5_2. Table S6. Down-regulated genes in the pathway of fatty acid degradation in Yl_5_3. Table S7. All strains can be obtained according to their standard numbers in laboratory.