Additional file 1 of Clinical Frailty Scale (CFS) indicated frailty is associated with increased in-hospital and 30-day mortality in COVID-19 patients: a systematic review and meta-analysis
Creators: name: Rottler, Máté
name: Ocskay, Klementina
name: Sipos, Zoltán
name: Görbe, Anikó
name: Virág, Marcell
name: Hegyi, Péter
name: Molnár, Tihamér
name: Erőss, Bálint
name: Leiner, Tamás
name: Molnár, Zsolt
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Mental Health

description: Additional file 1. Risk of bias assessment protocol. Figure S1. Risk of bias assessment for in-hospital mortality. Figure S2. Risk of bias assessment for 30-day mortality. Figure S3. Risk of bias assessment for average frailty comparing deceased and discharged COVID-19 patients. Figure S4. Risk of bias assessment for average frailty comparing COVID-19 patients who survived for 30-days vs who did not survive. Figure S5. Risk of bias assessment for ICU admission. Figure S6. Risk of bias assessment for length of hospital stay. Figure S7. 30-day and in-hospital mortality in patients with frailty indicated by CFS (1–3 vs 4–9). Figure S8. Mortality in frail patients indicated by CFS (1–3 vs 4–9), with studies grouped by age restriction. Figure S9. Leave-one-out sensitivity analysis for studies reporting mortality in patients with CFS 1–3 vs 4–9. Figure S10. Funnel plot for mortality in patients with CFS 1–3 vs 4–9. Figure S11. 30-day and in-hospital mortality in patients with CFS 1–4 vs 5–9. Figure S12. Mortality in patients with CFS 1–4 vs 5–9, with studies grouped by age restriction. Figure S13. Leave-one-out sensitivity analysis for studies reporting mortality in patients with CFS 1–4 vs 5–9. Figure S14. Funnel plot for mortality in patients with CFS 1–4 vs 5–9. Figure S15. Mortality comparing CFS 1–5 and CFS 6–9 groups, with studies grouped by country. Figure S16. 30-day and in-hospital mortality in patients with CFS 1–5 vs 6–9. Figure S17. Mortality comparing CFS 1–5 and CFS 6–9 groups, with studies grouped by age restriction. Figure S18. Leave-one-out sensitivity analysis for studies reporting mortality in patients with CFS 1–5 vs CFS 6–9. Figure S19. Funnel plot for mortality in patients with CFS 1–5 vs 6–9. Figure S20. Forest plot for weighted mean difference of CFS score for mortality with studies grouped by country. Figure S21. Forest plot for weighted mean difference of CFS score for mortality with studies grouped by follow-up. Figure S22. Leave-one-out sensitivity analysis for studies reporting average frailty indicated by CFS in survivors and non-survivors. Figure S23. Funnel plot for frailty difference in survivors vs non-survivors. Figure S24. Forest plot for mortality in patients with MPI 1 vs 2 and 3. Figure S25. Leave-one-out sensitivity analysis for studies reporting ICU admission in patients with CFS 1–3 vs 4–9. Figure S26. Funnel plot for ICU admission in patients with CFS 1–3 vs 4–9. Figure S27. Forest plot for ICU admission in patients with CFS 1–4 vs 5–9. Figure S28. Leave-one-out sensitivity analysis for studies reporting ICU admission in patients with CFS 1–4 vs 5–9. Figure S29. Funnel plot for ICU admission in patients with CFS 1–4 vs 5–9. Length of hospital stay: Summary of reported results.