cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
“Whatever Average Is”: Understanding African American Mothers’ Perceptions of Infant Weight, Growth, and Health
Creators: name: Bentley, Margaret E.
name: Thompson, Amanda L.
name: Adair, Linda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Biomedical researchers have raised concerns that mothers’ inability to recognize infant and toddler overweight poses a barrier to stemming increasing rates of overweight and obesity, particularly among low-income or minority mothers. Little anthropological research has examined the sociocultural, economic or structural factors shaping maternal perceptions of infant and toddler size or addressed biomedical depictions of maternal misperception as a “socio-cultural problem.” We use qualitative and quantitative data from 237 low-income, African-American mothers to explore how they define ‘normal’ infant growth and infant overweight. Our quantitative results document that mothers’ perceptions of infant size change with infant age, are sensitive to the size of other infants in the community, and are associated with concerns over health and appetite. Qualitative analysis documents that mothers are concerned with their children’s weight status and assess size in relation to their infants’ cues, local and societal norms of appropriate size, interactions with biomedicine, and concerns about infant health and sufficiency. These findings suggest that mothers use multiple models to interpret and respond to child weight. An anthropological focus on the complex social and structural factors shaping what is considered ‘normal’ and ‘abnormal’ infant weight is critical for shaping appropriate and successful interventions.
The ECtHR Talpis v. Italy Judgment
Creators: name: De Vido, Sara
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2017

description:

This comment is meant as a first reaction to the Talpis v. Italy judgment, rendered by the European Court of Human Rights on 2 March 2017, and an attempt to reflect on legal obligations States have in countering violence against women, in light of the Council of Europe Convention on Preventing and Combating Violence against Women and Domestic Violence, adopted in 2011 in Istanbul and entered into force in 2014.

description: Ricerche giuridiche
Worms on Paper using Open Microfluidics
Creators: name: Pandey, Santosh
Publisher: name: figshare
Year: 2023
Subjects: Bacteriology
Microbial genetics
Microbial ecology
Infectious agents
Diagnostic radiography
Dermatology
Clinimetrics
Endocrinology
Emergency medicine
Intensive care
Infectious diseases

description: Here we show an open microfluidic setup for drug screening of worms using paper microchips. https://doi.org/10.1063/1.5005829 https://aip.scitation.org/doi/10.1063/1.5005829
Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF
Creators: name: Der, C.J.
name: Kao, S.
name: Liu, B.
name: Zhang, H.
name: Burridge, K.
name: Whitehead, I.P.
name: Su, L.
name: Duus, K.
name: Wang, L.
name: Hart, M.J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: The long cytoplasmic tail of the human immunodeficiency virus (HIV)-1 transmembrane protein gp41 (gp41C) is implicated in the replication and cytopathicity of HIV-1 [1]. Little is known about the specific functions of gp41C, however. HIV-1 or simian immunodeficiency virus (SIV) mutants with defective gp41C have cell-type- or species-dependent phenotypes [2–6]. Thus, host factors are implicated in mediating the functions of gp41C. We report here that gp41C interacted with the carboxy-terminal regulatory domain of p115-RhoGEF [7], a specific guanine nucleotide exchange factor (GEF) and activator of the RhoA GTPase, which regulates actin stress fiber formation, activation of serum response factor (SRF) and cell proliferation [8,9]. We demonstrate that gp41C inhibited p115-mediated actin stress fiber formation and activation of SRF. An amphipathic helix region with a leucine-zipper motif in gp41C is involved in its interaction with p115. Mutations in gp41C leading to loss of interaction with p115 impaired HIV-1 replication in human T cells. These findings suggest that an important function of gp41C is to modulate the activity of p115-RhoGEF and they thus reveal a new potential anti-HIV-1 target.
Near-Infrared Spectroscopy of Young Galactic Supernova Remnants
Creators: name: Koo, Bon-Chul
name: Lee, Yong-Hyun
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Young Galactic supernova remnants (SNRs) are where we can observe closely the supernova (SN) ejecta and its interaction with circumstellar/interstellar medium. Therefore, they provide an opportunity to explore the explosion and the final stage of the evolution of massive stars. Near-infrared (NIR) emission lines in SNRs mostly originate from shocked dense material. In shocked SN ejecta, forbidden lines from heavy ions are prominent, while in shocked circumstellar/interstellar medium, [Fe II] and H2 lines are prominent. [Fe II] lines are strong in both media, and therefore [Fe II] line images provide a good starting point for the NIR study of SNRs. There are about twenty SNRs detected in [Fe II] lines, some of which have been studied in NIR spectroscopy. We will review the NIR [Fe II] observations of SNRs and introduce our recent NIR spectroscopic study of the young core-collapse SNR Cas A where we detected strong [P II] lines.
description: 4 pages, 4 figures, Invited talk at the 12th Asia-Pacific Regional IAU Meeting, Error in Figure 3 is fixed
Highlights from the PHENIX experiment
Creators: name: Csanad, Mate
Publisher: name: Zenodo
Year: 2022
Subjects: eunpc22
phenix
small systems
elliptic
flow
p+au
d+au
3he+au
correlations
p+al
raa
nuclear
modification
π0
cronin effect
direct photon
photon
J/Ψ
multiplicity
scaling
jet
energy loss
au+au
levy
hbt

description: Talk presented at the European Nuclear Physics Conference 2022
Temporal Philology
Creators: name: Kreuze, Wouter
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description:

Manuscript newsletters are by definition documents in motion. While they were written up, adapted and reassembled, they spread information all over the European continent. In the Florence State Archives, the documents are being preserved in separate folders reflecting their varied origins. It is known that these volumes have been rearranged during archival works in the centuries following their creation, the value of this distinction is therefore not wholly clear. By applying digital methodologies, however, we can calculate the dynamics of the travel times. This both tells something about the inner workings of this news system and also allows us to reapply this data to make an educated guess about the origin of these documents.

description: magazén
Measuring commissioners' willingness-to-pay for community based childhood obesity prevention programmes using a discrete choice experiment
Creators: name: Collinson, M.
name: Bryant, M.
name: Webb, E.J.D.
name: Farrin, A.J.
name: Burton, W.
name: Rutter, H.
name: Stevens, J.
name: Stamp, E.
name: Schofield, H.
Publisher: name: BioMed Central Ltd
Year: 2020

description: Background: In the UK, rates of childhood obesity remain high. Community based programmes for child obesity prevention are available to be commissioned by local authorities. However, there is a lack of evidence regarding how programmes are commissioned and which attributes of programmes are valued most by commissioners. The aim of this study was to determine the factors that decision-makers prioritise when commissioning programmes that target childhood obesity prevention. Methods: An online discrete choice experiment (DCE) was used to survey commissioners and decision makers in the UK to assess their willingness-to-pay for childhood obesity programmes. Results: A total of 64 commissioners and other decision makers completed the DCE. The impact of programmes on behavioural outcomes was prioritised, with participants willing to pay an extra £16,600/year if average daily fruit and vegetable intake increased for each child by one additional portion. Participants also prioritised programmes that had greater number of parents fully completing them, and were willing to pay an extra £4810/year for every additional parent completing a programme. The number of parents enrolling in a programme (holding the number completing fixed) and hours of staff time required did not significantly influence choices. Conclusions: Emphasis on high programme completion rates and success increasing children's fruit and vegetable intake has potential to increase commissioning of community based obesity prevention programmes.
Mps1 Phosphorylation of Dam1 Couples Kinetochores to Microtubule Plus Ends at Metaphase
Creators: name: Yates, John R.
name: Bloom, Kerry
name: Shimogawa, Michelle M.
name: Ess, Michael
name: Niessen, Sherry
name: Ruse, Cristian
name: Molk, Jeffrey N.
name: Muller, Eric G.D.
name: Davis, Trisha N.
name: Odde, David J.
name: Graczyk, Beth
name: Gardner, Melissa K.
name: Francis, Susan E.
name: White, Erin A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Duplicated chromosomes are equally segregated to daughter cells by a bipolar mitotic spindle during cell division. By metaphase, sister chromatids are coupled to microtubule (MT) plus ends from opposite poles of the bipolar spindle via kinetochores. Here we describe a phosphorylation event that promotes the coupling of kinetochores to microtubule plus ends.
From 1960 to the Present Day: The Influence of the Gestalt Theory on Didactic Devices for Language Teaching
Creators: name: Mezzadri, Marco
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description:

The present work discusses from a historical perspective the influence that the Gestalt Theory has had in Italy on the development of language teaching models from the 1960s to the present day. Different sources have thus been investigated, taking into account in particular the Venetian school of educational linguistics. The second part of the article is devoted to the presentation of a model created for teaching and learning Italian for study purposes, that is a practical proposal also indebted to the Gestalt theory. The model results from the attempt to transfer to the field of educational linguistics both findings made available by psychological research and by neuroscientific studies, in particular those which rely on the embodied nature of language.

description: EL.LE
Association of food parenting practice patterns with obesogenic dietary intake in Hispanic/Latino youth: Results from the Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth)
Creators: name: Stevens, J.
name: LeCroy, M.N.
name: Isasi, C.R.
name: Cai, J.
name: Mossavar-Rahmani, Y.
name: Perreira, K.M.
name: Albrecht, S.S.
name: Ward, D.S.
name: Castañeda, S.F.
name: Siega-Riz, A.M.
name: Gallo, L.C.
Publisher: name: Academic Press
Year: 2019

description: Some food parenting practices (FPPs)are associated with obesogenic dietary intake in non-Hispanic youth, but studies in Hispanics/Latinos are limited. We examined how FPPs relate to obesogenic dietary intake using cross-sectional data from 1214 Hispanic/Latino 8-16-year-olds and their parents/caregivers in the Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth). Diet was assessed with 2 24-h dietary recalls. Obesogenic items were snack foods, sweets, and high-sugar beverages. Three FPPs (Rules and Limits, Monitoring, and Pressure to Eat)derived from the Parenting strategies for Eating and Activity Scale (PEAS)were assessed. K-means cluster analysis identified 5 groups of parents with similar FPP scores. Survey-weighted multiple logistic regression examined associations of cluster membership with diet. Parents in the controlling (high scores for all FPPs)vs. indulgent (low scores for all FPPs)cluster had a 1.75 (95% CI: 1.02, 3.03)times higher odds of having children with high obesogenic dietary intake. Among parents of 12–16-year-olds, membership in the pressuring (high Pressure to Eat, low Rules and Limits and Monitoring scores)vs. indulgent cluster was associated with a 2.96 (95% CI: 1.51, 5.80)times greater odds of high obesogenic dietary intake. All other associations were null. Future longitudinal examinations of FPPs are needed to determine temporal associations with obesogenic dietary intake in Hispanic/Latino youth.
Quantifying origin and character of long-range correlations in narrative texts
Creators: name: Drożdż, Stanisław
name: Oświęcimka, Paweł
name: Kulig, Andrzej
name: Kwapień, Jarosław
name: Bazarnik, Katarzyna
name: Grabska-Gradzińska, Iwona
name: Rybicki, Jan
name: Stanuszek, Marek
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computation and Language (cs.CL)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: In natural language using short sentences is considered efficient for communication. However, a text composed exclusively of such sentences looks technical and reads boring. A text composed of long ones, on the other hand, demands significantly more effort for comprehension. Studying characteristics of the sentence length variability (SLV) in a large corpus of world-famous literary texts shows that an appealing and aesthetic optimum appears somewhere in between and involves selfsimilar, cascade-like alternation of various lengths sentences. A related quantitative observation is that the power spectra S(f) of thus characterized SLV universally develop a convincing `1/f^beta' scaling with the average exponent beta =~ 1/2, close to what has been identified before in musical compositions or in the brain waves. An overwhelming majority of the studied texts simply obeys such fractal attributes but especially spectacular in this respect are hypertext-like, "stream of consciousness" novels. In addition, they appear to develop structures characteristic of irreducibly interwoven sets of fractals called multifractals. Scaling of S(f) in the present context implies existence of the long-range correlations in texts and appearance of multifractality indicates that they carry even a nonlinear component. A distinct role of the full stops in inducing the long-range correlations in texts is evidenced by the fact that the above quantitative characteristics on the long-range correlations manifest themselves in variation of the full stops recurrence times along texts, thus in SLV, but to a much lesser degree in the recurrence times of the most frequent words. In this latter case the nonlinear correlations, thus multifractality, disappear even completely for all the texts considered. Treated as one extra word, the full stops at the same time appear to obey the Zipfian rank-frequency distribution, however.
description: 28 pages, 8 figures, accepted for publication in Information Sciences
Improved Laplace Approximation for Marginal Likelihoods
Creators: name: Ruli, Erlis
name: Sartori, Nicola
name: Ventura, Laura
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computation (stat.CO)
subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: Statistical applications often involve the calculation of intractable multidimensional integrals. The Laplace formula is widely used to approximate such integrals. However, in high-dimensional or small sample size problems, the shape of the integrand function may be far from that of the Gaussian density, and thus the standard Laplace approximation can be inaccurate. We propose an improved Laplace approximation that reduces the asymptotic error of the standard Laplace formula by one order of magnitude, thus leading to third-order accuracy. We also show, by means of practical examples of various complexity, that the proposed method is extremely accurate, even in high dimensions, improving over the standard Laplace formula. Such examples also demonstrate that the accuracy of the proposed method is comparable with that of other existing methods, which are computationally more demanding. An R implementation of the improved Laplace approximation is also provided through the R package iLaplace available on CRAN.
description: 24 pages
Research data management and sharing: the requirements of five major funders
Creators: name: Sébire, Fanny
Publisher: name: Zenodo
Year: 2023
Subjects: Research data
Data management plan
Open data
Research funders' policy

description: This document summarizes the requirements of five major funders with regard to: research data management documentation; opening or sharing of research data. The five funders: European Commission, French National Research Agency (ANR) , Bill & Melinda Gates Foundation, National Institutes of Health (NIH), Wellcome Trust.
RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress
Creators: name: Kim, Young-Bum
name: Boswell, Sarah A.
name: Der, Channing J.
name: Aaronson, Stuart A.
name: Kim, Hyung-Gu
name: Lee, Sam W.
name: Ridley, Anne J.
name: Dotto, G. Paolo
name: Ongusaha, Pat P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The Rho family of GTPases regulates many aspects of cellular behavior through alterations to the actin cytoskeleton [1-6]. The majority of the Rho family proteins function as molecular switches cycling between the active, GTP-bound, and the inactive, GDP-bound, conformations [1-6]. Unlike typical Rho family proteins, the Rnd subfamily members, including Rnd1, Rnd2, RhoE/Rnd3, and RhoH, are GTPase deficient, and thus expected to be constitutively active [7-10]. Here, we identify an unexpected role for RhoE/Rnd3 in the regulation of the p53-mediated stress response. We show that RhoE is a transcriptional p53 target gene, and that genotoxic stress triggers actin depolymerization, resulting in actin-stress fiber disassembly through p53-dependent RhoE induction. Silencing of RhoE induction in response to genotoxic stress maintains stress fiber formation and strikingly increases apoptosis, implying an antagonistic role for RhoE in p53-dependent apoptosis. We found that RhoE inhibits ROCK I (Rho associated kinase I) activity during genotoxic stress thereby suppressing apoptosis. We demonstrate that the p53-mediated induction of RhoE in response to DNA damage favors cell survival partly through inhibition of ROCK I-mediated apoptosis. Thus, RhoE is anticipated to function by regulating ROCK I signaling to control the balance between cell survival and cell death in response to genotoxic stress.
Wnt/Frizzled Signaling Controls C. elegans Gastrulation by Activating Actomyosin Contractility
Creators: name: Marston, Daniel J.
name: Halberstadt, Ari
name: Walston, Timothy
name: Goldstein, Bob
name: Lee, Jen-Yi
name: Hardin, Jeff
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Embryonic patterning mechanisms regulate the cytoskeletal machinery that drives morphogenesis, but there are few cases where links between patterning mechanisms and morphogenesis are well understood. We have used a combination of genetics, in vivo imaging, and cell manipulations to identify such links in C. elegans gastrulation. Gastrulation in C. elegans begins with the internalization of endodermal precursor cells in a process that depends on apical constriction of ingressing cells.
A Role for Cdc2- and PP2A-Mediated Regulation of Emi2 in the Maintenance of CSF Arrest
Creators: name: Tung, Jeffrey J.
name: Jackson, Peter K.
name: Margolis, Seth S.
name: Kornbluth, Sally
name: Guo, Yanxiang
name: Araki, Marito
name: Freel, Christopher D.
name: Yamano, Hiroyuki
name: Wu, Qiju
name: Asano, Maki
name: Tang, Wanli
name: Perry, Jennifer A.
name: Yamada, Ayumi
name: Wang, Michael Z.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Vertebrate oocytes are arrested in metaphase II of meiosis prior to fertilization by cytostatic factor (CSF). CSF enforces a cell cycle arrest by inhibiting the anaphase promoting complex (APC), an E3 ubiquitin ligase that targets Cyclin B for degradation. Although Cyclin B synthesis is ongoing during CSF arrest, constant Cyclin B levels are maintained. To achieve this, oocytes allow continuous slow Cyclin B degradation, without eliminating the bulk of Cyclin B, which would induce release from CSF arrest. However, the mechanism that controls this continuous degradation is not understood.
Longitudinal Associations between Body Mass Index during Young Adulthood, Subsequent Weight Change, and Incident Diabetes during Mid-and Older-Adulthood in Non-Hispanic White and African American Populations: The Atherosclerosis Risk in Communities Study
Creators: name: Couper, D.
name: Jenkins, G.P.
name: Lamichhane, A.P.
name: Stevens, J.
Publisher: name: Mary Ann Liebert Inc.
Year: 2020

description: Background: Excess body mass index (BMI) and weight gain are well-known risk factors for diabetes. Nevertheless, the associations of BMI and weight gain in young adulthood with subsequent diabetes in African Americans, and the standardized effects of these weight variables have not been well studied. Methods: We studied 12,672 white and African American men and women 45-64 years of age (i.e., during mid-adulthood) who participated in the Atherosclerosis Risk in Communities Study visit 1 (1987-1989), and were reexamined at three follow-up examinations. Associations between recalled BMI at age 25 (i.e., during young adulthood) and subsequent weight change with incident diabetes at ages 45 and above (i.e., during mid-adulthood to older adulthood) were examined using Cox proportional hazard models. Results: Over the 9-year follow-up, we identified 1,501 cases of incident diabetes. The incidence rates were higher among African Americans (men: 24.5 and women: 26.3 per 1,000 person-years) compared to whites (men: 16.3 and women: 10.5 per 1,000 person years). Compared to normal-weight individuals at age 25, those who were overweight or obese and those who gained more weight after age 25 had a higher risk of developing diabetes later in all four race-sex groups with the highest risk in African Americans. In the race-sex groups combined, the mutually adjusted hazard ratio for BMI at age 25 and percent weight change were 1.97 (1.79-2.17) and 2.89 (2.59-3.11), respectively, comparing the 85th to the 15th percentiles of the exposures. Conclusions: African Americans were at higher risk of diabetes than whites. Both higher BMI at age 25 and subsequent weight gain were independently associated with higher risk for diabetes in all the race-sex groups; however, overall weight gain was more potent than BMI.
Mind your methods: obesity trials and the consort guidelines
Creators: name: Stevens, J.
Publisher: name: Nature Publishing Group
Year: 2019

description: Last year, a nutrition scientist at a prestigious American university was charged with academic misconduct owing to the use of flawed research methods. One of the methods that led to the misconduct charge was “P-hacking”, defined by Simonsohn et al. as conducting multiple analyses but only revealing the results with P values < 0.05. Thus, P-hacking is “data dredging” or a “fishing expedition” followed by selective reporting, with P values singled out as the driver of the selection process. Selective reporting can lead to a type of publication bias that can result in false-positive findings that are unable to be replicated.
Almost algebraic actions of algebraic groups and applications to algebraic representations
Creators: name: Bader, Uri
name: Duchesne, Bruno
name: Lécureux, Jean
Publisher: name: arXiv
Year: 2014
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics

description: Let G be an algebraic group over a complete separable valued field k. We discuss the dynamics of the G-action on spaces of probability measures on algebraic G-varieties. We show that the stabilizers of measures are almost algebraic and the orbits are separated by open invariant sets. We discuss various applications, including existence results for algebraic representations of amenable ergodic actions. The latter provides an essential technical step in the recent generalization of Margulis-Zimmer super-rigidity phenomenon due to Bader and Furman.
description: Correction of a small mistake in Proposition 5.3
Differential susceptibility of S and M phase cyclin/CDK complexes to inhibitory tyrosine phosphorylation in yeast
Creators: name: Zyla, Trevin R.
name: Marquitz, Aron R.
name: Bardes, Elaine S.G.
name: Keaton, Mignon A.
name: Rudolph, Johannes
name: Freel, Christopher D.
name: Lew, Daniel J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Several checkpoint pathways employ Wee1-mediated inhibitory tyrosine phosphorylation of cyclin-dependent kinases (CDKs) to restrain cell-cycle progression. Whereas in vertebrates this strategy can delay both DNA replication and mitosis, in yeast cells only mitosis is delayed. This is particularly surprising because yeasts, unlike vertebrates, employ a single family of cyclins (B-type) and the same CDK to promote both S phase and mitosis. The G2-specific arrest could be explained in two fundamentally different ways: tyrosine phosphorylation of cyclin/CDK complexes could leave sufficient residual activity to promote S phase, or S phase-promoting cyclin/CDK complexes could somehow be protected from checkpoint-induced tyrosine phosphorylation.
An algebraic model for commutative HZ-algebras
Creators: name: Richter, Birgit
name: Shipley, Brooke
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 55P43

description: We show that the homotopy category of commutative algebra spectra over the Eilenberg-Mac Lane spectrum of the integers is equivalent to the homotopy category of E-infinity-monoids in unbounded chain complexes. We do this by establishing a chain of Quillen equivalences between the corresponding model categories. We also provide a Quillen equivalence to commutative monoids in the category of functors from the category of finite sets and injections to unbounded chain complexes.
description: to appear in AGT
Pericentric Chromatin Is an Elastic Component of the Mitotic Spindle
Creators: name: Bloom, Kerry
name: Bouck, David C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Prior to chromosome segregation, the mitotic spindle bi-orients and aligns sister chromatids along the metaphase plate. During metaphase, spindle length remains constant, suggesting that spindle forces (inward and outward) are balanced. The contribution of microtubule motors, regulators of microtubule dynamics, and cohesin to spindle stability has been previously studied. In this study, we examine the contribution of chromatin structure on kinetochore positioning and spindle length control. Following nucleosome depletion, by either histone H3 or H4 repression, spindle organization was examined using live cell fluorescence microscopy.
Esporre «integralmente la dottrina» e regolarsi «secondo l’opportunità»
Creators: name: Vian, Giovanni
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description:

The Italian Risorgimento process saw the Apostolic Penitentiary, generally accustomed to operating with great confidentiality, rising to a prominent ‘public’ role. It was in the context of the Roman Question that the Holy See had to deal with the introduction of the new Italian Penal Code (commonly called ‘Zanardelli Code’), which was approved in June 1889 and came into force at the beginning of the following year. This article offers a reconstruction of the reaction of the Apostolic Penitentiary and the Holy See to the publication of the Code.

description: JoMaCC
Fixed or random? On the reliability of mixed‐effects models for a small number of levels in grouping variables
Creators: name: Oberpriller, Johannes
name: de Souza Leite, Melina
name: Pichler, Maximilian
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: fixed effects, generalized linear models, hierarchical models, mixed-effects models, multilevel models, random effects
subject: 570 Biowissenschaften, Biologie

description: Biological data are often intrinsically hierarchical (e.g., species from different genera, plants within different mountain regions), which made mixed-effects models a common analysis tool in ecology and evolution because they can account for the non-independence. Many questions around their practical applications are solved but one is still debated: Should we treat a grouping variable with a low number of levels as a random or fixed effect? In such situations, the variance estimate of the random effect can be imprecise, but it is unknown if this affects statistical power and type I error rates of the fixed effects of interest. Here, we analyzed the consequences of treating a grouping variable with 2–8 levels as fixed or random effect in correctly specified and alternative models (under- or overparametrized models). We calculated type I error rates and statistical power for all-model specifications and quantified the influences of study design on these quantities. We found no influence of model choice on type I error rate and power on the population-level effect (slope) for random intercept-only models. However, with varying intercepts and slopes in the data-generating process, using a random slope and intercept model, and switching to a fixed-effects model, in case of a singular fit, avoids overconfidence in the results. Additionally, the number and difference between levels strongly influences power and type I error. We conclude that inferring the correct random-effect structure is of great importance to obtain correct type I error rates. We encourage to start with a mixed-effects model independent of the number of levels in the grouping variable and switch to a fixed-effects model only in case of a singular fit. With these recommendations, we allow for more informative choices about study design and data analysis and make ecological inference with mixed-effects models more robust for small number of levels.
Quantum Criticality in the 122 Iron Pnictide Superconductors Emerging from Orbital-Selective Mottness
Creators: name: Das, S. D.
name: Laad, M. S.
name: Craco, L.
name: Gillett, J.
name: Tripathi, V.
name: Sebastian, S. E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The twin issues of the nature of the normal state and competing order(s) in the iron arsenides are central to understanding their unconventional, high-Tc superconductivity. We use a combination of transport anisotropy measurements on detwinned Sr(Fe(1-x)Co(x))2As2 single crystals and local density approximation plus dynamical mean field theory (LDA + DMFT) calculations to revisit these issues. The peculiar resistivity anisotropy and its evolution with x are naturally interpreted in terms of an underlying orbital-selective Mott transition (OSMT) that gaps out the dxz or dyz states. Further, we use a Landau-Ginzburg approach using LDA + DMFT input to rationalize a wide range of anomalies seen up to optimal doping, providing strong evidence for secondary electronic nematic order. These findings suggest that strong dynamical fluctuations linked to a marginal quantum-critical point associated with this OSMT and a secondary electronic nematic order constitute an intrinsically electronic pairing mechanism for superconductivity in Fe arsenides.
description: 9 pages, revtex4-1, published version
Gestion et partage des données de recherche : les exigences de cinq grands financeurs
Creators: name: Sébire, Fanny
Publisher: name: Zenodo
Year: 2023
Subjects: Données de recherche
Plan de gestion des données
Ouverture des données
Politique des financeurs de la recherche

description: Cette fiche pratique récapitule les exigences de cinq financeurs en ce qui concerne : La documentation liée à la gestion des données de recherche ; L’ouverture ou le partage des données de recherche. Les cinq financeurs : Commission européenne, Agence Nationale de la recherche (ANR), Bill & Melinda Gates Foundation, National Institutes of Health (NIH), Wellcome Trust.
An Expanded Biological Repertoire for Ins(3,4,5,6)P4 through its Modulation of ClC-3 Function
Creators: name: Nelson, Deborah J.
name: Gentzsch, Martina
name: Shears, Stephen B.
name: Mitchell, Jennifer
name: Zhang, Guangping
name: Wang, Xueqing
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Ins(3,4,5,6)P4 inhibits plasma membrane Cl− flux in secretory epithelia [1]. However, in most other mammalian cells, receptor-dependent elevation of Ins(3,4,5,6)P4 levels is an “orphan” response that lacks biological significance [2]. We set out to identify Cl− channel(s) and/or transporter(s) that are regulated by Ins(3,4,5,6)P4 in vivo. Several candidates [3-5] were excluded through biophysical criteria, electrophysiological analysis, and confocal immunofluorescence microscopy. Then, we heterologously expressed ClC-3 in the plasma membrane of HEK293-tsA201 cells; whole-cell patch-clamp analysis showed Ins(3,4,5,6)P4 to inhibit Cl− conductance through ClC-3. Next, we heterologously expressed ClC-3 in the early endosomal compartment of BHK cells; by fluorescence ratio imaging of endocytosed FITC-transferrin, we recorded intra-endosomal pH, an in situ biosensor for Cl− flux across endosomal membranes [6]. A cell-permeant, bioactivatable Ins(3,4,5,6)P4 analog elevated endosomal pH from 6.1 to 6.6, reflecting inhibition of ClC-3. Finally, Ins(3,4,5,6)P4 inhibited endogenous ClC-3 conductance in postsynaptic membranes of neonatal hippocampal neurones. Among other ClC-3 functions that could be regulated by Ins(3,4,5,6)P4 are tumor cell migration [7], apoptosis [8], and inflammatory responses [9]. Ins(3,4,5,6)P4 is a ubiquitous cellular signal with diverse biological actions.
Coactivation of G Protein Signaling by Cell-Surface Receptors and an Intracellular Exchange Factor
Creators: name: Lee, Michael J.
name: Dohlman, Henrik G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: G protein-coupled receptors (GPCRs) mediate responses to a broad range of chemical and environmental signals. In yeast a pheromone-binding GPCR triggers events leading to the fusion of haploid cells. In general, GPCRs function as guanine nucleotide exchange factors (GEFs); upon agonist binding the receptor induces a conformational change in the G protein α subunit, resulting in exchange of GDP for GTP and in signal initiation. Signaling is terminated when GTP is hydrolyzed to GDP [1]. This well-established paradigm has in recent years been revised to include new components that alter the rates of GDP release, GTP binding [2-8], and GTP hydrolysis [9, 10]. Here we report the discovery of a non-receptor GEF, Arr4. Like receptors, Arr4 binds directly to the G protein, accelerates guanine nucleotide exchange, and stabilizes the nucleotide-free state of the α subunit. Moreover, Arr4 promotes G protein-dependent cellular responses including mitogen-activated protein kinase (MAPK) phosphorylation, new gene transcription and mating. In contrast to known GPCRs, however, Arr4 is not a transmembrane receptor, but rather a soluble intracellular protein. Our data suggest that intracellular proteins function in cooperation with mating pheromones to amplify G protein signaling, thereby leading to full pathway activation.
The Unsung Kingdom Translation Project
Creators: name: Mantelli, Alessandro
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description:

This paper presents the experience of the design of a didactic activity for the translation of a Japanese video game in Italian, carried out in 2020 during the first year of the Japanese language course of the Master’s Degree Programme in Language and Civilisation of Asia and Mediterranean Africa at Ca’ Foscari University. The described protocol allows the design of video game translation sessions as a teaching activity, overcoming some typical technical and organisational problems. One important issue this paper addresses involves the possibility of reviewing the translation within the game, which is fundamental to understanding how to translate texts for this medium. The paper will also give an overview of the translation issues that students encountered during the activity and of how they solved them. Finally, the results of a survey will show whether the implemented protocol and classroom activity were satisfactory for the students and how they can be improved.

description: Annali di Ca’ Foscari. Serie orientale
Bandpass calibration of a wideband spectrometer using coherent pulse injection
Creators: name: Patra, Nipanjana
name: Bray, Justin D.
name: Roberts, Paul
name: Ekers, Ron D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We present a relatively simple time domain method for determining the bandpass response of a system by injecting a nanosecond pulse and capturing the system voltage output. A pulse of sub-nanosecond duration contains all frequency components with nearly constant amplitude up to 1 GHz. Hence, this method can accurately determine the system bandpass response to a broadband signal. In a novel variation on this impulse response method, a train of pulses is coherently accumulated providing precision calibration with a simple system. The basic concept is demonstrated using a pulse generator-accumulator setup realised in a Bedlam board which is a high speed digital signal processing unit. The same system was used at the Parkes radio telescope between 2-13 October 2013 and we demonstrate its powerful diagnostic capability. We also present some initial test data from this experiment.
description: 11 pages, 9 figures, submitted to Experimental Astronomy
Changes in Cardiovascular Disease Risk Factors with Unintentional Versus Intentional Weight Loss: The Coronary Artery Risk Development in Young Adults Study
Creators: name: Cai, J.
name: Stevens, J.
name: Cui, Z.
name: Lewis, C.E.
Publisher: name: Mary Ann Liebert Inc.
Year: 2019

description: It is well known that total and intentional weight loss (IWL) are associated with reductions in cardiovascular disease (CVD) risk factors, however, associations with unintentional weight loss (UWL) have not been studied. Methods: We examined annual changes in blood pressure and lipids associated with UWL versus IWL in 576 participants from the Coronary Artery Risk Development in Young Adults (CARDIA) study who had lost weight over one of two time intervals (i.e., study years 5-7 or 7-10) and reported whether the weight loss was intentional at the end of the interval. Results: After adjusting for age, sex, race, and field center, an annual weight loss smaller than 6% resulted in small improvements in lipids that were similar regardless of intentionality. When annual weight loss was ≥6%, UWL was associated with less reduction in total cholesterol (-0.2 vs. -10.4 mg/dL), low-density lipoprotein cholesterol (-3.2 vs. -9.4 mg/dL), and triglycerides (-0.5 vs. -19.0 mg/dL) compared with IWL. Intentionality was not associated with the size of changes in blood pressure (systolic blood pressure: -2.7 vs. -2.0 mmHg; diastolic blood pressure: -2.2 vs. -1.3 mmHg) and high-density lipoprotein cholesterol (3.2 vs. 2.7 mg/dL). Conclusions: Substantial UWL may be accompanied or preceded by other biological changes in this young adult population that alter changes in CVD risk factors that are associated with IWL.
“Everybody Knew Čuoppomáddu Stories”. On Human/Other‑Than-Human Relations in Stuornjárga as Revealed Through the Márka‑Sámi Toponyms
Creators: name: De Vivo, Erika
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description:

The Sámi people share their ancestral homeland (Sápmi, sub/Arctic Europe) not only with animals, plants, trees, rocks, colonial-settlers and more recent immigrants but also with other-than-human beings. For centuries, the Sámi have co-constructed Sápmi’s landscape with these entities through respect and reciprocity. Despite enforced conversion, elements of Sámi Indigenous worldviews persisted. Enshrined in placenames, collective memory of interactions with other-than-human beings has been passed down through generations. The paper highlights the importance that toponyms have in transmitting cultural values, identity, and a sense of belonging.

description: Lagoonscapes
Distinct Face-Processing Strategies in Parents of Autistic Children
Creators: name: Spezio, Michael L.
name: Piven, Joseph
name: Adolphs, Ralph
name: Parlier, Morgan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: In his original description of autism, Kanner [1] noted that the parents of autistic children often exhibited unusual social behavior themselves, consistent with what we now know about the high heritability of autism [2]. We investigated this so-called “Broad Autism Phenotype” in the parents of children with autism, who themselves did not have a diagnosis of any psychiatric illness. Building on recent quantifications of social cognition in autism [3], we investigated face processing using the “Bubbles” method [4] to measure how viewers make use of information from specific facial features in order to judge emotions. Parents of autistic children who were assessed as socially aloof (N=15), a key component of the phenotype [5], showed a remarkable reduction in processing the eye region in faces, together with enhanced processing of the mouth, compared to a control group of parents of neurotypical children (N=20), as well as to non-aloof parents of autistic children (N=27, whose pattern of face processing was intermediate). The pattern of face processing seen in the Broad Autism Phenotype showed striking similarities to that previously reported to occur in autism [3], and for the first time provides a window into the endophenotype that may result from a subset of the genes that contribute to social cognition.
Prevalence of Optimal Metabolic Health in American Adults: National Health and Nutrition Examination Survey 2009-2016
Creators: name: Stevens, J.
name: Araújo, J.
name: Cai, J.
Publisher: name: Mary Ann Liebert Inc.
Year: 2019

description: Background: Several guidelines for cardiometabolic risk factor identification and management have been released in recent years, but there are no estimates of current prevalence of metabolic health among adults in the United States. We estimated the proportion of American adults with optimal cardiometabolic health, using different guidelines. Methods: Data from the National Health and Nutrition Examination Survey 2009-2016 were analyzed (n = 8721). Using the most recent guidelines, metabolic health was defined as having optimal levels of waist circumference (WC <102/88 cm for men/women), glucose (fasting glucose <100 mg/dL and hemoglobin A1c <5.7%), blood pressure (systolic <120 and diastolic <80 mmHg), triglycerides (<150 mg/dL), and high-density lipoprotein cholesterol (≥40/50 mg/dL for men/women), and not taking any related medication. Results: Changing from ATP III (Adult Treatment Panel III) guidelines to more recent cut points decreased the proportion of metabolically healthy Americans from 19.9% (95% confidence interval [CI]: 18.3-21.5) to 12.2% (95% CI: 10.9-13.6). Dropping WC from the definition increased the percentage of adults with optimal metabolic health to 17.6%. Characteristics associated with greater prevalence of metabolic health were female gender, youth, more education, never smoking, practicing vigorous physical activity, and low body mass index. Less than one-third of normal weight adults were metabolically healthy and the prevalence decreased to 8.0% and 0.5% in overweight and obese individuals, respectively. Conclusions: Prevalence of metabolic health in American adults is alarmingly low, even in normal weight individuals. The large number of people not achieving optimal levels of risk factors, even in low-risk groups, has serious implications for public health.
A Novel Adaptive Possibilistic Clustering Algorithm
Creators: name: Xenaki, Spyridoula D.
name: Koutroumbas, Konstantinos D.
name: Rontogiannis, Athanasios A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In this paper a novel possibilistic c-means clustering algorithm, called Adaptive Possibilistic c-means, is presented. Its main feature is that {\it all} its parameters, after their initialization, are properly adapted during its execution. Provided that the algorithm starts with a reasonable overestimate of the number of physical clusters formed by the data, it is capable, in principle, to unravel them (a long-standing issue in the clustering literature). This is due to the fully adaptive nature of the proposed algorithm that enables the removal of the clusters that gradually become obsolete. In addition, the adaptation of all its parameters increases the flexibility of the algorithm in following the variations in the formation of the clusters that occur from iteration to iteration. Theoretical results that are indicative of the convergence behavior of the algorithm are also provided. Finally, extensive simulation results on both synthetic and real data highlight the effectiveness of the proposed algorithm.
The Novelist and Social Catholicism: George Fonsegrive’s Le Fils de l’Esprit
Creators: name: Talar, Charles
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description:

George Fonsegrive (1852-1917), noteworthy for his work in philosophy and apologetics, also wrote several novels under the pen name of Yves Le Querdec. For the most part they can be classed as realist social novels with a didactic purpose. Le Fils de l’Esprit (1905) falls among these. While didactic novels are not generally remembered for their literary merit, the very qualities that consign them to marginal interest attract the interest of the historian. In the details of life and human interaction that novels portray may be communicated the texture of the times and feeling of a period that more analytic treatments convey. As a novelist, Fonsegrive offers perspectives on a French Catholicism that was undergoing significant transformation in its social action.

description: JoMaCC
Eucharistic concelebration & Adomnán’s Life of Saint Columba
Creators: name: Ryan, Fergus
Publisher: name: Ex Fonte - Journal of Ecumenical Studies in Liturgy
Year: 2023

description: The author considers whether the late seventh–century account by Adomnán of Saint Columba’s invitation to the bishop Cronan to “break this bread alone according to the episcopal rite” serves as an indication of concelebration among presbyters and of presbyters with a bishop. He examines Roman and Gallican documents of similar time periods for traces of Eucharistic concelebration and differences in episcopal and presbyteral celebration in the rituals of breaking the consecrated loaf after the Eucharistic Prayer. He concludes that there is every reason to consider the incident described by Adomnán as a witness to concelebration both by presbyters among themselves and with a presiding bishop.
description: Ex Fonte - Journal of Ecumenical Studies in Liturgy, Bd. 2 (2023)