cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
An Introduction to MPEG-G: The First Open ISO/IEC Standard for the Compression and Exchange of Genomic Sequencing Data
Creators: name: Voges, Jan
name: Hernaez, Mikel
name: Mattavelli, Marco
name: Ostermann, Jorn
Publisher: name: New York, NY [u.a.] : Inst.
Year: 2021
Subjects: subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: computational biology
subject: data compression
subject: DNA
subject: genomics
subject: standardization
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: The development and progress of high-throughput sequencing technologies have transformed the sequencing of DNA from a scientific research challenge to practice. With the release of the latest generation of sequencing machines, the cost of sequencing a whole human genome has dropped to less than 600. Such achievements open the door to personalized medicine, where it is expected that genomic information of patients will be analyzed as a standard practice. However, the associated costs, related to storing, transmitting, and processing the large volumes of data, are already comparable to the costs of sequencing. To support the design of new and interoperable solutions for the representation, compression, and management of genomic sequencing data, the Moving Picture Experts Group (MPEG) jointly with working group 5 of ISO/TC276 'Biotechnology' has started to produce the ISO/IEC 23092 series, known as MPEG-G. MPEG-G does not only offer higher levels of compression compared with the state of the art but it also provides new functionalities, such as built-in support for random access in the compressed domain, support for data protection mechanisms, flexible storage, and streaming capabilities. MPEG-G only specifies the decoding syntax of compressed bitstreams, as well as a file format and a transport format. This allows for the development of new encoding solutions with higher degrees of optimization while maintaining compatibility with any existing MPEG-G decoder.
Impact of the COVID-19 pandemic on Clostridioides difficile infection in a tertiary healthcare institution in Belgium
Creators: name: Tossens, Bastien
name: Barthelme, Philippe
name: Briquet, Caroline
name: Belkhir, Leila
name: Ngyuvula, Eléonore
name: Soumillion, Kate
name: Verroken, Alexia
name: Rodriguez-Villalobos, Hector
name: Delmée, Michel
name: Anantharajah, Ahalieyah
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Clostridioides difficile infection (CDI) causes the greatest number of healthcare-associated infectious diarrhoea. CDIs are transmitted by direct and indirect patient-to-patient contact and risk increases with the use of antibiotics. Since early 2020, the COVID-19 pandemic has affected healthcare systems in many ways including substantial changes in hygiene behaviour. The aim of this study was to assess whether CDI incidence differed during the COVID-19 pandemic compared to a year before. All tests for suspected CDI cases were recorded for a hospital in Brussels, Belgium. The percentage of CDI-positive results and incidences (total and healthcare-associated (HA)-CDI)) for years 2019, 2020, 2021, and 2022 were calculated. Antibiotic consumption was analysed for years 2019 and 2020. Since the COVID-19 pandemic struck, a significant reduction of up to 39% was observed in the number of Clostridioides difficile stool tests in our hospital. A significant decrease in the percentage of positive tests and a 50% decrease in the incidence of CDI (total and HA-CDI) was found for 2020 compared with 2019 and confirmed for years 2021 and 2022. The decrease in CDI incidence was mostly marked in haematology, nephrology, and gastroenterology units. No significant change in the use of antibiotics was found. The global decrease in CDI incidence observed in our hospital was not associated with a change in the use of antibiotics. The control measures implemented to prevent COVID-19 transmission may explain a reduction in CDI incidence. An underdiagnosis of CDI cannot be excluded.
Ateísmo de pena, ateísmo de chumbo. Jean Meslier entre o silêncio e a explosão
Creators: name: Baudry, Hervé
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2017

description: Resumo Este texto foi apresentado durante uma sessão do Seminário do Prof. Luís Abreu, « Travessias do anticlericalismo ». Trata-se de aclimatar a questão do pensamento ateu moderno. Sem pretender fazer uma história do ateísmo em Portugal, problematiza-se a questão para futuros trabalhos em volta de Jean Meslier (1664-1729). As primeiras traduções foram imprimidas no fim do séc. XIX. Mas ficam muito fragmentárias, à imagem das pseudo-edições do século anterior. Daí, esboça-se a história do texto do Mémoire, das cópias manuscritas às primeiras impressões. Palavras-Chave: Anticlericalismo, Ateísmo, Jean Meslier Abstract This text, presented during the Seminary “Anticlerical crossings” by Prof. Luís Abreu, deals with the question of atheism in modern thought. Far from reporting its history in Portugal, it attempts to build its problematization in view of future works about Jean Meslier (1664-1729). The first translations of his Mémoire were printed at the end of the nineteenth century, but they are as partial as the pseudo-editions of the previous century. Hence, a historical sketch of the text of Meslier’s Mémoire, from the manuscripts to the first printings. Keywords: Atheism, Enlightenment, Jean Meslier
description: Revista Lusófona de Ciência das Religiões, v. 1 n. 20 (2017): «O anticlericalismo e os desafios da contemporaneidade ao Cristianismo»
Students', parents' and teachers' perceptions of the aims of schooling
Creators: name: Shanahan, Lindsay
Publisher: name: CQUniversity
Year: 2022
Subjects: subject: 130399 Specialist Studies in Education not elsewhere classified
subject: FOS: Educational sciences

description: This study considers various aims and purposes of education espoused by sociologists, philosophers and educators at various stages throughout history. The variety of aims suggested means that many are incompatible with each other and were held often by contemporary thinkers belonging to different schools of thought. the present study set out to find out what current educators, students, and parents involved in education of years 8,9 and 10 students in a metropolitan high school considered were the aims of education. The purpose of the study was to elucidate any variance between these major stakeholder groups in what they considered were the main aims and purposes of the educational enterprise during these critical final years of compulsory schooling. A survey was developed by adapting an instrument previously developed by Ashton, Keen, Davis and Holly (1975). The survey consisted of a list of 72 aims of education on which respondents were asked to indicate, using a five point Likert scale, the relative degree of importance which each considered should be ascribed to that particular aim of education. The study found that, although there were minor variances in which aims some of the stakeholder groups considered important, there was a surprising degree of homogeneity in the aims the stakeholders espoused. Academic aims, and those aims promoting social behaviours were considered as high priorities while foreign language acquisition was a very low priority for all stakeholders. The final discussion focuses on the meaning of these results for the future direction of education.
Sorting photon wave packets using temporal-mode interferometry based on multiple-stage quantum frequency conversion
Creators: name: Reddy, D. V.
name: Raymer, M. G.
name: McKinstrie, C. J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: All classical and quantum technologies that encode in and retrieve information from optical fields rely on the ability to selectively manipulate orthogonal field modes of light. Such manipulation can be achieved with high selectivity for polarization modes and transverse-spatial modes. For the time-frequency degree of freedom, this could efficiently be achieved for a limited choice of approximately orthogonal modes, i.e. non-overlapping bins in time or frequency. We recently proposed a method that surmounts the selectivity barrier for sorting arbitrary orthogonal temporal modes [Opt. Lett. {\bf 39}, 2924 (2014)] using cascaded interferometric quantum frequency conversion in nonlinear optical media. We call this method temporal-mode interferometry, as it has a close resemblance to the well-known separated-fields atomic interferometry method introduced by Ramsey. The method has important implications for quantum memories, quantum dense coding, quantum teleportation, and quantum key distribution. Here we explore the inner workings of the method in detail, and extend it to multiple stages with a concurrent asymptotic convergence of temporal-mode selectivity to unity. We also complete our analysis of pump-chirp compensation to counter pump-induced nonlinear phase-modulation in four-wave mixing implementations.
description: Accepted for publication in Phys. Rev. A. 2015
DOSSIÊ “ANTICLERICALISMO”
Creators: name: Machado De Abreu, Luís
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2017

description: INTRODUÇÃO NOVOS E VELHOS ANTICLERICALISMOS A julgar pelo franco acolhimento que gestos, palavras e decisões do Papa Francisco encontram hoje na generalidade da opinião pública, o anticlericalismo, incluindo a sua versão antijesuítica, estaria a sair de cena a passo acelerado. Católicos, crentes de outras confissões religiosas, e até agnósticos e ateus, parecem escutar a mensagem e seguir com apreço as frequentes intervenções do papa. E não deixa de ser surpreendente que se esbocem atitudes de incómodo, de reserva e mesmo de indignada contestação vindas agora, pasme-se, dos mais intransigentes sequazes das teologias do mercado. Dir-se-ia que novos anticlericais vêm ocupar o lugar que os anticlericais clássicos estariam a deixar vazio por sentirem que os argumentos com que sustentavam a causa foram, a pouco e pouco, enfraquecendo e perdendo oportunidade. Os teólogos do mercado e da finança, com a sua plêiade de acólitos, parecem agora em vias de se constituírem em novos adversários do clero. Em tempos de crise, a Igreja, com clero e laicado movidos pelas urgências da solidariedade social e pastoralrmente mobilizados pelo magistério do Papa Francisco, estaria a increpar os interesses egoístas das poderosas forças do mercado. Ao proceder assim, a Igreja andaria a invadir território alheio e a usurpar as temporalidades que pertencem a César. (...)
description: Revista Lusófona de Ciência das Religiões, v. 1 n. 20 (2017): «O anticlericalismo e os desafios da contemporaneidade ao Cristianismo»
Viscous flow-finite elasticity interaction : variational formulation and finite element approximation
Creators: name: Ghattas, Omar
name: Xiaogang  Li
name: Carnegie Mellon University.Engineering Design Research Center.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90799 Environmental Engineering not elsewhere classified
subject: FOS: Environmental engineering
subject: 90599 Civil Engineering not elsewhere classified
subject: FOS: Civil engineering

description: Abstract: "We consider the problem of the interaction of a stationary viscous fluid with an elastic solid that undergoes large deformation. The fluid is modeled by the stationary incompressible Navier- Stokes equations in an Eulerian frame of reference, while a Lagrangian reference frame and large deformation-small strain theory is used for the solid. A variational formulation of the problem is developed that insures satisfaction of continuity of interface tractions and velocities. The variational formulation is approximated by a Galerkin finite element method, yielding a system of nonlinear algebraic equations in unknown fluid velocities and pressures and solid displacements. A Newton-like method is introduced for solution of the discrete system. The method employs a modified Jacobian that enables decomposition into separate fluid and solid subdomains. This domain decomposition avoids possible ill-conditioning of the Jacobian, as well as the need to compute and store geometric coupling terms between fluid and interface shape. The capability of the methodology is illustrated by solution of a problem of the flow-induced large deformation of an elastic infinite cylinder."
VENEZIA E LA MEMORIA DELLA GRANDE GUERRA (1918-1926)
Creators: name: GALANTI, STEFANO
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: La ricerca analizza le rappresentazioni della Prima guerra mondiale sviluppatesi a Venezia nel periodo 1918-1926. L'indagine riguarda contestualmente i fenomeni di elaborazione, circolazione, negoziazione e strumentalizzazione riconducibili alla produzione di immagini nel contesto sociale, politico e culturale della citt�. L'obiettivo dello studio � innanzitutto quello di rintracciare i diversi agenti sociali nella sfera pubblica e in quella privata, proponendo una mappatura delle comunit� che presero parte attiva alla costruzione della memoria durante il primo dopoguerra. In secondo luogo, l'indagine mira ad analizzare le pratiche, i linguaggi e i costumi della rimembranza collettiva elaborati da questo tipo di agenti, cos� come le conseguenze riportate nei loro campi d'azione (per esempio, il cambiamento delle retoriche e degli spazi urbani). Infine ? focalizzando l'attenzione sul caso di studio di Venezia ? si vogliono descrivere ed esaminare le diverse rappresentazioni del conflitto, offrendo un approfondimento sulla dimensione della pluralit� e sui percorsi complessi della memoria. Oltre alla dimensione del lutto, la ricerca fa riferimento a temi quali la celebrazione della vittoria, il multiforme processo della smobilitazione nel corso della prima fase del periodo postbellico (e l'intreccio di due differenti eventi storici ricordati: la Rivoluzione Veneziana del 1848-49 e la Grande Guerra), l'uso pubblico della memoria per le rivendicazioni italiane nella regione adriatica, il passaggio dalla fine dell'et� liberale alla dittatura fascista, l'azione di figure sociali quali reduci, mutilati e vedove di guerra e ? da una differente prospettiva di analisi ? comunit� religiose, �lites locali, movimenti politici.
A resample-replace lasso procedure for combining high-dimensional markers with limit of detection
Creators: name: Wang, Jinjuan
name: Zhao, Yunpeng
name: Tang, Larry L.
name: Mueller, Claudius
name: Li, Qizhai
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Hematology

description: In disease screening, a biomarker combination developed by combining multiple markers tends to have a higher sensitivity than an individual marker. Parametric methods for marker combination rely on the inverse of covariance matrices, which is often a non-trivial problem for high-dimensional data generated by modern high-throughput technologies. Additionally, another common problem in disease diagnosis is the existence of limit of detection (LOD) for an instrument – that is, when a biomarker's value falls below the limit, it cannot be observed and is assigned an NA value. To handle these two challenges in combining high-dimensional biomarkers with the presence of LOD, we propose a resample-replace lasso procedure. We first impute the values below LOD and then use the graphical lasso method to estimate the means and precision matrices for the high-dimensional biomarkers. The simulation results show that our method outperforms alternative methods such as either substitute NA values with LOD values or remove observations that have NA values. A real case analysis on a protein profiling study of glioblastoma patients on their survival status indicates that the biomarker combination obtained through the proposed method is more accurate in distinguishing between two groups.
Equilibrium free energy differences at different temperatures from a single set of nonequilibrium transitions
Creators: name: Patra, Puneet Kumar
name: Bhattacharya, Baidurya
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Crook's Fluctuation Theorem and Jarzynski equality are immensely powerful tools in obtaining equilibrium properties through non-equilibrium transition between two equilibrium states. In this letter, we propose an extension to the Crook's fluctuation theorem for transition between two non-equilibrium steady states (NESS). Using the proposed theorem, we show that it is possible to obtain free energy differences of multiple equilibrium states from a single set of data obtained from the transition between two NESS. The results are verified using numerical simulations by employing Nose-Hoover dynamics and a single dimensional $ϕ^4$ chain. The equations are cast in a manner that makes it possible to do experimental verification. The proposed method can provide free-energy difference for a range of temperature, and consequently is much faster than either the Jarzynski equality or the Crooks's fluctuation theorem.
description: Modified version 2; Contains additional validation
A Negação do Ego no budismo chinês ou orientações para uma ética do Budismo Humanista de Taiwan
Creators: name: Durazzo, Leandro
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2017

description: Resumo Embasando-se em discussões clássicas das Ciências Sociais – como o estudo sobre a noção de pessoa em Marcel Mauss – este artigo busca traçar um breve roteiro através de dois hemisférios de pensamento, apresentando uma crítica epistemológica à categoria ocidental de pessoa (donde Ego) com respaldo em uma tradição também antiga e em constante desenvolvimento, a saber, o Budismo indiano e seus desdobramentos em China e Taiwan. Para isso, analisamos elementos do Sutra Diamante e do SatyasiddhiSastra de Harivarman, desembocando num panorama contemporâneo das ordens budistas taiwanesas. Palavras-chave: Budismo; Noção de pessoa; Ética; China; Taiwan Abstract Relying upon some classical debates on Social Sciences, as Marcel Mauss’ notion of person, this paper aims to drawn a brief route through Western and Eastern thoughts, presenting an epistemological critique over Western category of person (whence Ego) from another ancient and constantly-changing tradition, i.e. Buddhism from India to its Chinese and Taiwanese developments. For this purpose, we will briefly review some elements of Diamond Sutra and Harivarman’s SatyasiddhiSastra, making our way through the contemporary landscape of Taiwanese Buddhist orders. Keywords: Buddhism; Notion of person; Ethics; China; Taiwan
description: Revista Lusófona de Ciência das Religiões, v. 1 n. 20 (2017): «O anticlericalismo e os desafios da contemporaneidade ao Cristianismo»
A unified approach for the simultaneous synthesis of reaction, energy and separation systems
Creators: name: Subash  Balakrishna
name: Biegler, Lorenz T.
name: Carnegie Mellon University.Engineering Design Research Center.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: Abstract: "Previous studies on process integration have generally considered reaction and separation as processes that occur sequentially in a flowsheet. In this paper, a unified formalism is presented for the synthesis of reaction-separation systems, while ensuring 'optimal' energy management. The synthesis model stems from a target-based approach for reactor networks due to an earlier study. It is shown that by postulating a species dependent residence time distribution function, one can arrive at a general representation for a reaction-separation network. Optimization of this distribution function leads to a separation profile as a function of time along the length of the reactor. The synthesis model is formulated as a mixed integer optimal control problem, where the integer variables account for the fixed costs of separation. The control profiles include the temperature, the separation profile, and residence time distribution defined for the network. Costs for maintaining a separation profile are handled through a separation index (defined to model the intensity of separation), and a fixed charge for any separation between two components in the reaction mixture. Also, using an energy targeting formulation, the maintenance of the optimal temperature profile is integrated to the energy flows within the flowsheet. Strategies based on simultaneous optimization and model solution are presented for the optimization problem and demonstrated for two case studies."
Parametric inference of the process capability index
Creators: name: Saha, Mahendra
name: Dey, Sanku
name: Nadarajah, Saralees
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Process capability indices (PCIs) are most effective devices/techniques used in industries for determining the quality of products and performance of manufacturing processes. In this article, we consider the PCI Cpc which is based on the proportion of conformance and is applicable to normally as well as non-normally and continuous as well as discrete distributed processes. In order to estimate the PCI Cpc when the process follows exponentiated exponential distribution, we have used five classical methods of estimation. The performances of these classical estimators are compared with respect to their biases and mean squared errors (MSEs) of the index Cpc through simulation study. Also, the confidence intervals for the index Cpc are constructed using five bootstrap confidence interval (BCIs) methods. Monte Carlo simulation study has been carried out to compare the performances of these five BCIs in terms of their average width and coverage probabilities. Besides, net sensitivity (NS) analysis for the given PCI Cpc is considered. We use two data sets related to electronic and food industries and two failure time data sets to illustrate the performance of the proposed methods of estimation and BCIs. Additionally, we have developed PCI Cpc using aforementioned methods for generalized Rayleigh distribution.
Activation of the SiC Surface for Vapor Phase Lubrication by Fe Chemical Vapor Deposition from Fe(CO)5
Creators: name: Daxing  Ren
name: Dougyoung  Sung
name: Gellman, Andrew J
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: The feasibility is demonstrated of a new approach to the vapor phase lubrication of ceramics using organophosphorus compounds. The
surface of SiC is shown to be unreactive for the decomposition of trimethylphosphite, (CH3O)3P, a simple model for organophosphorus
vapor phase lubricants such as tricresylphosphate. In order to activate the surface of SiC it has been exposed to Fe(CO)5 at a temperature
of 600 K. Chemical vapor deposition serves as a means of depositing Fe on the SiC surface. The Fe-modified SiC surface is then shown
to induce the decomposition of adsorbed (CH3O)3P. The mechanism of (CH3O)3P decomposition is similar to that observed on Fe(110)
surfaces modified by the presence of oxygen. It is initiated by P–O bond cleavage to produce adsorbed methoxy groups, CH3O(ad),
which then decompose by β-hydride elimination resulting in H2, CO, H2CO, and CH3OH desorption. It is suggested that chemical vapor
deposition of metals using high vapor pressure metal-containing compounds such as Fe(CO)5 can serve as a mechanism for continuous,
in situ activation of ceramic surfaces for vapor phase lubrication in high temperature engines.
Peer review under review - a statistical study on proposal ranking at ESO
Creators: name: Patat, Ferdinando
Publisher: name: Zenodo
Year: 2023
Subjects: Peer review
European Southern Observatory
Telescope time allocation

description: I present and discuss a comprehensive statistical statistical study on proposal ranking at the European Southern Observatory (ESO), based on a sample of about 15000 proposals, submitted by more than 3000 Principal Investigators over 8 years. The proposals were reviewed by more than 500 referees, who assigned over 140000 grades in about 200 panel sessions. After briefly discussing the process, I present and discuss a number of statistical indicators, providing a robust evaluation of the level of subjectivity and reproducibility of the review process. Part of the material was already published (Paper I; https://doi.org/10.1088/1538-3873/aac463). The rest is in preparation (Paper II) and should be submitted soon to PASP.
An efficient method for optimal design of large-scale integrated chemical production sites with endogenous uncertainty
Creators: name: Terrazas-Moreno, Sebastian
name: Grossmann, Ignacio E.
name: Wassick, John
name: Bury, Scott J.
name: Akiya, Naoko
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: Integrated sites are tightly interconnected networks of large-scale chemical processes. Given the large-scale network structure of these sites, disruptions in any of its nodes, or individual chemical processes, can propagate and disrupt the operation of the whole network. Random process failures that reduce or shut down production capacity are among the most common disruptions. The impact of such disruptive events can be mitigated by adding parallel units and/or intermediate storage. In this paper, we address the design of large-scale, integrated sites considering random process failures. In a previous work (Terrazas-Moreno et al., 2010), we proposed a novel mixed integer linear programming (MILP) model to maximize the average production capacity of an integrated site while minimizing the required capital investment. The present work deals with the solution of large-scale problem instances for which a strategy is proposed that consists of two elements. On one hand, we use Benders decomposition to overcome the combinatorial complexity of the MILP model. On the other hand, we exploit discrete-rate simulation tools to obtain a relevant reduced sample of failure scenarios or states. We first illustrate this strategy in a small example. Next, we address an industrial case study where we use a detailed simulation model to assess the quality of the design obtained from the MILP model.
High contrast imaging of reversibly switchable fluorescent proteins via temporally unmixed Multispectral Optoacoustic Tomography (tuMSOT)
Creators: name: Stiel, Andre C
name: Dean-Ben, X Luis
name: Jiang, Yuanyuan
name: Ntziachristos, Vasilis
name: Razansky, Daniel
name: Westmeyer, Gil G
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Photocontrol of reversibly switchable fluorescent proteins (RSFPs) was used to program optoacoustic signal time courses that were temporally unmixed to increase the proteins contrast-to-noise-ratios (CNRs) in optoacoustic imaging. In this way, two variants of the RSFP Dronpa with very similar optoacoustic spectra could be readily discriminated in the presence of highly absorbing blood. Addition of temporal unmixing to multispectral optoacoustic tomography (tuMSOT) in conjunction with synthetic or genetically controlled photochromic contrast agents and customized photoswitching schedules can increase the performance of multiplexed and high contrast molecular optoacoustic imaging.
Do Direito à (Des)crenca
Creators: name: Ferreira Da Cunha, Paulo
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2017

description: Resumo A questão dos direitos e liberdades relacionados com as convicções religiosas e as perspetivas filosóficas sobre a transcendência encontra-se ainda muito imbuída de preconceitos apaixonados. É muito difícil e poderá eventualmente até revelar-se perigoso (desde logo porque estigmatizador) opinar neste contexto, mesmo em ambiente geral democrático e pluralista. Há uma incompreensão política persistente da realidade religiosa e uma incompreensão religiosa da realidade política, talvez maior ainda nos tempos atuais. Neste artigo se procura ensaística e tentativamente ponderar a necessidade de levar em conta a importância civilizacional do legado e da ação de organismos religiosos, com a necessária igualdade (ou equidade) entre os credos, e direitos análogos dos descrentes, agnósticos e indiferentes. A conclusão é a de que se não vê quem, além de um Estado laico, possa assumir o papel de árbitro, com um papel irrepreensível, sem servilismo e sem anticlericalismo. Só assim também os grupos religiosos aprofundariam a sua diferença específica de espiritualidade numinosa. Num tempo em que se lançam dúvidas sobre essa característica, sobretudo em algumas chamadas "seitas". Palavras-Chave: Liberdade Religiosa, Laicismo, Laicidade, Direito à Crença, Direito à descrença, Espirtualidades Abstract The question of rights and freedoms related to religious convictions and philosophical perspectives on transcendence is still very much imbued with passionate prejudices. It is very difficult and may even dangerous (henceforth because of stigmatizing) to express opinions in this context, even in a democratic and pluralistic general environment. There is a persistent political misunderstanding of religious reality and a religious misunderstanding of political reality, perhaps even greater in present times. In this article we seek (with an essay style and approach) consider the need to take into account the civilizational importance of the legacy and the action of religious organisms, with the necessary of equality (or equity) between the creeds, and analogous rights of the unbelieving, agnostic and indifferent. The conclusion is that one does not see who, besides a secular state, can assume the role of arbiter, with an irreproachable role, without servility and without anticlericalism. Only in this way would religious groups further their specific difference in numinous spirituality. At a time when doubts are cast on this characteristic of some of those groupe, especially some of those called "sects". Keywords: Religious Freedom, Laicism, Laicity, Right to Belief, Right to Disbelief, Spirituality
description: Revista Lusófona de Ciência das Religiões, v. 1 n. 20 (2017): «O anticlericalismo e os desafios da contemporaneidade ao Cristianismo»
REALISM AND THE GREAT LAKES REGION OF AFRICA'S UNSTABLE SECURITY: AN ANALYSIS AT THREE LEVELS
Creators: name: Jacques, Magabo
name: Patrick, Mushitsi
name: Vérène, Niyomana
name: Régis, Bayihaye
name: Jean-Claude, Ntizoyimana
Publisher: name: SSJOURNAL
Year: 2025
Subjects: Realism, Great Lakes Region, Security dilemma, Power maximization, Rivalry cooperation, Natural resources

description: This paper examines the enduring security challenges in the Great Lakes Region of Africa through the lens of realist theory. By analyzing the interplay of power, interests, and state behaviour at the individual, national, and international levels, the study sheds light on the factors contributing to the region's persistent instability. The paper argues that the pursuit of self-interest by leaders, the competition among states, and the influence of external powers have exacerbated tensions and fueled conflict. Despite various peace initiatives and international interventions, the region remains vulnerable to renewed cycles of violence. A more comprehensive understanding of the region's security dynamics requires a nuanced analysis incorporating realist and non-realist perspectives.
Structure of quantum and broadcasting nonlocal correlations
Creators: name: Saha, Debashis
name: Pawłowski, Marcin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The multipartite setting offers much more complexity of nonlocality than the bipartite one. We analyze the structure of tripartite nonlocal correlations by proposing inequalities satisfied by each type: bilocal, broadcasting and quantum, but violated by the other two. One of the inequalities satisfied by broadcasting correlations is generalized for multipartite systems. The study of its quantum mechanical violation reveals that Greenberger-Horne-Zeilinger-like states exhibit new, powerful correlations.
NO SHONEEN: GAELIC GAMES AND THE ATHLETIC HERO IN THE IRISH PERIODICAL PRESS
Creators: name: OGLIARI, ELENA
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: Attraverso il filtro della letteratura periodica destinata ai ragazzi, questa tesi esamina alcuni aspetti della cultura sportiva irlandese per come venne a delinearsi durante la ?Lunga Gestazione? dell?indipendenza dell?Irlanda, ovvero nel periodo precedente alla creazione dello Stato Libero d?Irlanda nel 1922. Un periodo, vale la pena ricordarlo, che vide il rinascimento della cultura gaelica, lo scoppio della Sollevazione della Settimana Santa nel 1916 e il trionfo del partito Sinn F�in sui Redmonditi nelle elezioni del 1918. Concentrandosi su questo tipo di genere editoriale, infatti, � possibile far affiorare una rete complessa di immagini, simboli e discorsi relativi alla cultura sportiva irlandese. La tesi � suddivisa in due parti. La prima � dedicata alla presentazione degli obiettivi di questo studio, dello stato dell?arte, del corpus preso in esame e della metodologia. L?analisi testuale, seppur in maggior parte rivolta ai testi di fiction e agli articoli dei periodici, si estende ad altri generi di scrittura, quali le corrispondenze private, i dibattiti parlamentari, i rapporti governativi. La giustapposizione di testi dalla natura cos� multiforme permette di cogliere gli atteggiamenti prevalenti e le usanze socioculturali dell?epoca, nonch� le implicazioni politiche e culturali insite nell?ascesa del sistema sportivo in Irlanda. La seconda parte di No Shoneen: Gaelic Games e Athletic Hero nella Irish Periodical Press invece, descrive nel dettaglio le tappe che hanno portato all?emergere di un sistema sportivo irlandese e come i giochi di matrice gaelica divennero significanti culturali, segnalando la specificit� dell?Irlanda in patria e all?estero. Questa sezione tratta altres� delle ragioni sottostanti la comparsa, all?inizio del Ventesimo secolo, di una figura che si potrebbe definire dell??Atleta-Eroe?. Gli ultimi due capitoli di questo lavoro, infatti, espongono la connessione tra l?ascesa del sistema sportivo irlandese e l?investimento politico e culturale sui giovani irlandesi per dimostrare come i giochi gaelici aiutassero gli irlandesi nella formazione di un nuovo ideale di fanciullezza. Pi� specificamente, laddove il quarto capitolo si concentra sulla concezione del giovane atleta come artefice dell?indipendenza irlandese e pietra angolare di una nuova comunit� ? una concezione a sua volta imperniata sulla nozione di pratica sportiva come forma di preparazione militare ?, l?ultimo capitolo delinea i contorni di tale mascolinit� idealizzata e incarnata dal giovane atleta gaelico. L?obiettivo � mostrare come il corpo vigoroso dell?atleta sia stato opportunamente rappresentato ed esaltato in modo da neutralizzare le caratterizzazioni stereotipate degli irlandesi come inferiori e ?bisognosi? del dominio anglosassone.
A Ideia Nacionalocalizante de Portugal na Obra do Abade de Baçal
Creators: name: Eduardo Franco, José
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2017

description: Resumo O nosso artigo analisará o legado historiográfico do Padre Francisco Manuel Alves, Abade de Baçal, na perspetiva de procurar compreender qual o ideário que lhe subjaz na construção de uma ideia de Portugal, valorizando o papel do local e do regional no quadro nacional. Palavras-chave: História, Ideografia de Portugal, Bragança, nação. Abstract Our article will analyse the historiographical legacy of Father Francisco Manuel Alves, Abbot of Baçal, in the perspective of trying to understand his ideology in the construction of an idea of Portugal, valuing the role of local and regional in a national framework. Keywords: History, Ideography of Portugal, Bragança, nation.
description: Revista Lusófona de Ciência das Religiões, v. 1 n. 20 (2017): «O anticlericalismo e os desafios da contemporaneidade ao Cristianismo»
A Ideia de Foedus Pacificum em Sebastião de Magalhães Lima
Creators: name: Eduardo Franco, José
name: Lucas Da Silva, Cristiana Isabel
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2017

description: Resumo Sebastião de Magalhães Lima foi um verdadeiro apóstolo do ideário federalista republicano e pacifista. Ao longo da sua vida, escreveu inúmeros textos em defesa de uma Federação Ibérica como primeira etapa para a construção dos Estados Unidos da Humanidade e a realização da Paz Universal. O breve estudo que se segue pretende sintetizar o pensamento federalista e pacifista de Magalhães Lima, tendo como base dois textos da sua autoria, publicados no final do século XIX, O Federalismo (1898) e Paz e Arbitragem (1897), embora não descurando outras obras da sua autoria. Atentaremos especialmente à influência do pensamento de Immanuel Kant, Proudhon, Pi y Margal e Teófilo Braga. Palavras-Chaves: Federalismo; República; Paz; Iberismo; Humanidade Abstract Sebastião de Magalhães Lima was a true apostle of the republican and pacifist federalist ideology. Throughout his life, he wrote countless texts defending an Iberian Federation as the first step towards the construction of the United States of Humanity and the achievement of Universal Peace. The following brief study intends to synthesize the federalist and pacifist thought of Magalhães Lima, based on two of his texts, published in the late nineteenth century, Federalismo (1898) and Paz e Arbitragem (1897), although not neglecting his other works. We will mainly analyse the influence of the thought of Immanuel Kant, Proudhon, Pi y Margal and Teófilo Braga. Keywords: Federalism; Republic; Peace; Iberianism; Humanity
description: Revista Lusófona de Ciência das Religiões, v. 1 n. 20 (2017): «O anticlericalismo e os desafios da contemporaneidade ao Cristianismo»
SgpDec: Cascade (De)Compositions of Finite Transformation Semigroups and Permutation Groups
Creators: name: Egri-Nagy, Attila
name: Mitchell, James D.
name: Nehaniv, Chrystopher L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20M20

description: We describe how the SgpDec computer algebra package can be used for composing and decomposing permutation groups and transformation semigroups hierarchically by directly constructing substructures of wreath products, the so called cascade products.
description: 7 pages, 4 figures, presented at the 4th International Congress on Mathematical Software, http://sgpdec.sf.net
O Discurso sobre o Estrangeiro como causa da decadência de Portugal Antero de Quental e António Sardinha
Creators: name: Lucas Da Silva, Cristiana Isabel
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2017

description: Resumo O tema da decadência nacional foi uma das questões mais debatidas entre a elite intelectual portuguesa, com maior incidência na segunda metade do século XIX e primeiras décadas do século XX, independentemente da sua afiliação ideológica. Antero de Quental e António Sardinha, não obstante as diferenças que os separam, perscrutaram as causas da decadência nacional, associando-a à influência ou domínio de determinadas entidades ou circunstâncias estranhas à índole nacional. Neste sentido, tanto as Causas da decadência dos povos peninsulares nos últimos três séculos como O valor raça: introdução a uma campanha nacional constituem discursos que oferecem uma tipificação do estrangeiro, identificado como causa da decadência. Palavras-chaves: Decadência, Estrangeiro, História, Alteridade. Abstract The theme of national decadence was one of the most debated issues among the Portuguese intellectual elite, with a higher incidence in the second half of the nineteenth century and the first decades of the twentieth century, regardless of their ideological affiliation. Antero de Quental and António Sardinha, despite the differences that separate them, have examined the causes of national decadence, associating them with the influence or domination of certain entities or circumstances that are foreign to the national character. In this sense, both the Causas da decadência dos povos peninsulares nos últimos três séculos as O valor raça: introdução a uma campanha nacional are discourses that offer a typification of the foreigner, identified as the cause of the decadence. Keywords: Decadence, Foreign, History, Otherness.
description: Revista Lusófona de Ciência das Religiões, v. 1 n. 20 (2017): «O anticlericalismo e os desafios da contemporaneidade ao Cristianismo»
STRUCTURAL AND FUNCTIONAL INSIGHTS ON THE DROSOPHILA TNFR GRINDELWALD, COUPLING LOSS OF CELL POLARITY AND NEOPLASTIC GROWTH
Creators: name: PALMERINI, VALENTINA
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: Disruption of polarity and impairment of programmed cell death are signalling pathways of advanced epithelial tumors, whose progression often involves the activation of signalling controlled by TNF receptors, such as the JNK pathway. However, the link between loss of polarity and JNK pathway still remains elusive. In a disc-specific rn>avl RNAi screen aimed at finding new genes involved in neoplastic onset, a novel Drosophila TNFR was identified, named Grindelwald (Grnd). Grnd and the unique fly TNF Eiger activate the JNK pathway, and induce apoptosis or malignancy in a cell context-dependent manner. My PhD project focused on the characterization of the molecular mechanisms underlying Grnd activation and transduction of the JNK pathway. Upon binding to Eiger, Grnd recruits to the intracellular membrane Traf2, the most upstream component of the JNK pathway, and activates the JNK cascade. To shed light on the mechanism of Grnd activation by Eiger, I determined the crystal structure of the extracellular domain (ECD) of Grnd, in isolation and in complex with Eiger. Grnd-ECD comprises a single cysteine-rich domain, organized in two modules, named X2 and C2, and stabilized by disulphide bridges. The crystal structure of the Eiger:Grnd complex showed that the Eiger-TNF domain folds in a typical ?jelly-roll? antiparallel ?-sheet, and forms hetero-hexamers with three Grnd molecules. To map the interacting surface between Grnd and Eiger, we engineered point mutations and performed binding assays revealing that Thr51, His66-Asn67 of Grnd and Asp337, His388-Arg391, and Arg396-Arg401 of Eiger are essential for the nanomolar affinity between the ligand and the receptor. In vitro studies suggest that glycosylation on Asn332 of Eiger lowers the affinity between Eiger and Grnd. We are currently generating collaboratively Grnd mutant flies to assess the relevance of the Eiger-Grnd interaction in activating the JNK pathway and inducing the small-eye phenotype, or in promoting malignancy in scrib-/-;rasV12 clones. Previous results showed that the JNK pathway was activated in polarity-deficient cells to drive neoplastic growth. In the rn>avl RNAi screen, Grnd, but not Eiger, was necessary for the JNK pathway to be induced. I showed that Grnd directly interacts with the polarity protein Veli, to promote hyper-proliferation and invasiveness. Collectively, these findings depict Grnd as the first TNFR able to couple cell polarity with tumor overgrowth. One major goal of my project was also the identification of a Grnd orthologue in human, able to couple polarity and signal transduction. Biochemical analyses revealed that Fas is the only TNFR interacting with Veli and with the basolateral polarity protein Dlg1, and provided evidence that Dlg1 compete with Veli for binding to Fas. The relevance of these interactions for the Fas biology is currently under investigation.
Critical Success Factors of BI Project Implementation: An Implementation Methodology Perspective
Creators: name: Ranjbarfard, Mina
name: hatami, zeynab
Publisher: name: figshare
Year: 2022
Subjects: subject: 150301 Business Information Management (incl. Records, Knowledge and Information Management, and Intelligence)
subject: FOS: Economics and business
subject: 150302 Business Information Systems

description: َAim: The purpose of this paper is to identify Critical Success Factors (CSFs) for Business Intelligence (BI) implementation projects by studying the existing BI project implementation methodologies and to compare these methodologies based on the identified CSFs.Background: The implementation of BI project has become one of the most important technological and organizational innovations in modern organizations. The BI project implementation methodology provides a framework for demonstrating knowledge, ideas and structural techniques. It is defined as a set of instructions and rules for implementing BI projects. Identifying CSFs of BI implementation project can help the project team to concentrate on solving prior issues and needed resources. Methodology: Firstly, the literature review was conducted to find the existing BI project implementation methodologies. Secondly, the content of the 13 BI project implementation methodologies was analyzed by using thematic analysis method. Thirdly, for examining the validation of the 20 identified CSFs, two questionnaires were distributed among BI experts. The gathered data of the first questionnaire was analyzed by content validity ratio (CVR) and 11 of 20 CSFs were accepted as a result. The gathered data of the second questionnaire was analyzed by fuzzy Delphi method and the results were the same as CVR. Finally, 13 raised BI project implementation methodologies were compared based on the 11 validated CSFs.