cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Adverse Events from Tobacco/Nicotine Dependence and Impacts on Cancer Patient Clinical Experiences
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Several millions of adults in California use tobacco products, including vaping devices. At the same time, hundreds of thousands of adults in California have either had cancer or will be diagnosed with cancer in the next year. Cancer patients who have used tobacco products may present in a medical setting with different symptoms and comorbidities, may experience different outcomes, and may have other patient care characteristics that differ from those for cancer patients who do not use tobacco products. It has been well-documented that use of tobacco increases risk of cancer, and the consumption of tobacco-related carcinogens is expected to increase the severity of cancer upon clinical presentation. However, use of tobacco products (including vaping devices) also presents risk for adverse events, including nicotine poisoning, burns, heart palpitations, and pulmonary issues such as e-cigarette, or vaping, product use associated lung injury (EVALI). While some of these have been documented, individuals who experience adverse events may not go to a clinical provider, which presents a limitation on records which can be used by researchers to understand tobacco-related adverse events. Indeed, thorough population-based research has not been conducted to enumerate tobacco-related adverse events and their distribution. As part of this study, we will conduct a population-based survey to ascertain the types of adverse events experienced by adults who use tobacco/vaping products, enabling a broader understanding of the health issues experienced by users of these products. We will then assess the differences in medical procedures and clinical observations between cancer patients with tobacco/nicotine dependence (TND) and a comparison sample of cancer patients without TND. Variables analyzed will include imaging and blood tests, drugs/treatments administered, and clinical outcomes such as comorbidities and death. Investigators will use a large dataset of electronic health records (EHR) with approximately 500 million data points for 500 thousand patients across the five medical centers of the University of California. Demographic characteristics will be collected in both survey and EHR, enabling an understanding of health disparities. This research will catalyze critical evidence needed to improve care of cancer patients having current/former use of tobacco products.
Adapting Project Towards No Nicotine for Virtual Delivery in Ethnically-Diverse Afterschool Settings
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Use of electronic nicotine delivery systems (ENDS) among youth in California and nationally has reached epidemic proportions in a relatively short period of time. Currently, one in five high school students regularly use ENDS. E-cigarette manufacturers have developed and marketed new flavored, disposable e-cigarette products that circumvent regulations on JUULs and other reusable vaping devices, which resulted in a 400% increase in use among middle school students. For many youth, middle school represents the developmental period in which experimentation and use of ENDS begins and therefore is the ideal time to expose such youth to e-cigarette and other tobacco use prevention programming. Afterschool programs are a promising environment to implement such programming, yet limited research has been conducted in this setting.
 With previous funding from TRDRP and following a community-engaged approach, we developed Project Towards No Nicotine (Project TNN), based on the comprehensive social influences/life skills model of prevention, and assessed its effect on e-cigarette and tobacco knowledge and use outcomes among an ethnically-diverse population of middle school-aged students in afterschool program settings in Los Angeles. Our preliminary assessment of Project TNN showed promising results in regards to increasing youth understanding about vaping and associated health consequences.
 Through our current application, we propose to further revise Project TNN and develop a virtual version of the curriculum that could be delivered remotely in afterschool settings by a trained health educator. A virtual version of Project TNN will increase availability of needed e-cigarette and other tobacco use prevention programming in underserved, ethnically-diverse communities in an effort to address inequities in program availability. The curriculum will also counteract the effects of the commercial tobacco epidemic among many of the youth populations targeted by such marketing tactics. We propose to conduct a three-arm cluster randomized trial to compare in-person and virtual delivery of Project TNN to a wait-list control condition. The study is a collaboration between UCLA, USC, and BREATHE SoCal, a non-profit advocacy organization with experience implementing lung health prevention programing in afterschool programs, and the Boys and Girls Clubs of Greater Los Angeles.
American Indian Community Engagement in the Vaping Endgame
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: American Indians (AI) experience the highest prevalence of cigarette smoking among all ethnic or racial groups in California. Despite Tribal prevention and education efforts to reduce commercial tobacco use, growing evidence demonstrates electronic cigarette (EC) use, or vaping, continues to pose an increased risk for AI youth and their families living in rural, isolated, and low-income Tribal communities. The University of Southern California (USC) and Resources for Indian Student Education, Inc. (RISE) has an established and long-standing community-academic research partnership focused on commercial tobacco research in the Modoc County Tribal community. Our research revealed that vaping among AI youth is a serious public health concern (e.g., vaping in school restrooms, lack of awareness of harmful effects). USC and RISE will address Tribal and school concerns regarding the high youth vaping use, and lack of awareness among parents, family, and community about vaping by offering a community-based campaign for parent, family, and community as well as an intervention for AI middle and high school students. A pilot test to both interventions will be conducted with an emphasis on cultural competence and pedagogy that will resonate with the AI community. The parent/community education campaign and youth vaping intervention will increase knowledge, improve attitudes, positively influence behavioral intentions, and expand awareness of traditions that naturally prevent vaping initiation, promote nicotine/vaping cessation, and support positive behaviors. A triangulation paradigm will define authentic data (interviews, observations, and questionnaires) on vaping attitudes, perceptions, behaviors and consequences from AI youth, families, and community to create an effective, respected, and successful intervention and education campaign. USC and RISE will work with AI youth, a community advisory board, and schools to build a stronger, healthier community.
Developing new inhibitors of mutant KRAS to treat tobacco-related lung cancers
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: KRAS is a protein that acts as an on/off switch for cell growth. When KRAS is mutated, cells can grow uncontrollably and develop into cancers. KRAS mutations occur more frequently in the lungs of smokers, leading to deadly diseases such as non-small cell lung cancer (NSCLC). Historically, lung cancer patients with these mutations have had few treatment options and a poor prognosis.
 Developing drugs that bind to and inhibit mutant KRAS has proven challenging. Recently, however, scientists have found a way to inhibit one of the commonly mutated forms, KRAS-G12C. The G12C mutation introduces the amino acid cysteine onto the surface of KRAS which can be targeted by covalent drugs such as Sotorasib. Sotorasib possesses a cysteine-reactive "warhead", which forms a permanent bond with the G12C cysteine residue and locks KRAS in the "off" state. Sotorasib has now been clinically approved as a treatment for patients with G12C-driven NSCLC, demonstrating that covalent inhibition of KRAS mutants is an effective strategy for combating cancers.
 The major shortcoming of this approach arises because these cysteine-targeted drugs do not work against the other common KRAS mutations (such as G12D/V), which lack a suitable cysteine residue. Furthermore, resistance to Sotorasib has already been observed and frequently occurs via the acquisition of additional mutations that prevent covalent cysteine binding through a variety of mechanisms. Taken together, patients suffering from intractable, KRAS-mutant lung cancer represent a major unmet clinical need. Inhibitors that covalently inhibit KRAS without utilizing a cysteine residue could potentially meet this need and revolutionize the treatment landscape for KRAS-driven lung cancer.
 Lysine is an alternative amino acid for covalent targeting that is found in the binding pocket of all KRAS mutants. Recently, our research group and others have developed and characterised new classes of covalent inhibitors that can target lysine residues selectively. In this fellowship I will develop the first lysine-targeted covalent inhibitors of KRAS. By testing their ability to inhibit all the common KRAS mutations, including those arising from Sotorasib resistance, I will lay the foundations for next-generation lung cancer treatments.
Building a tobacco control pipeline for Mexican-American first generation college students
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: This proposal is to the Smoke and Vape Free Scholars Initiative (SVFSI) Planning Award. If awarded, I will spend the next year preparing a SVFSI program application focusing on creating a tobacco control research and service-learning partnership between California State University Fresno (Fresno State) and the University of California Merced (UC Merced). This program will help to promote research and advocacy surrounding the ongoing local Community of Excellence in Tobacco Control programs that local lead agencies have begun to develop at the behest of the California Department of Public Health.

 Over the next year this partnership will design a SVFSI program to recruit 15 first generation college students (students whose parents have not completed a 4-year degree) of Mexican descent who are enrolled in Fresno State over a 4 year period. The program will focus on integrating students into tobacco control research by (1) delivering culturally competent tobacco control curriculum, (2) placing students into tobacco control/advocacy and research projects that support the objectives of local Community of Excellence in Tobacco Control programs, and (3) providing students with research mentors who engage in tobacco-related research that either take place in the San Joaquin Valley or focuses on the Latino community.

 Project activities would include (1) assembling a project team and identifying faculty and staff to serve as possible program administrators and research mentors, (2) planning the structure of the program and theme, (3) developing a scholar recruitment and selection strategy and plan, (4) identifying tobacco control/advocacy projects that align with local Community of Excellence in Tobacco Control programs, (5) designing a culturally competent tobacco control seminar, and (6) working with career services and other relevant departments to develop a plan for mentoring students in their career path. This will allow us to develop and write a strong program application.

 The deliverable at the end of the year would be a strong application to the SVFSI Program.
Precision medicine in allergic disease—food allergy, drug allergy, and anaphylaxis—PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology
Creators: name: Khan, D.
name: Castells, M.
name: Worm, M.
name: Simon, H.‐U.
name: Poulsen, L. K.
name: Torres, M. J.
name: Burks, W.
name: Nadeau, K. C.
name: Sampson, H. A.
name: Lemanske, R. F.
name: Bindslev‐Jensen, C.
name: Muraro, A.
Publisher: name: Wiley
Year: 2017

description:
This consensus document summarizes the current knowledge on the potential for precision medicine in food allergy, drug allergy, and anaphylaxis under the auspices of the PRACTALL collaboration platform. PRACTALL is a joint effort of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology, which aims to synchronize the European and American approaches to allergy care. Precision medicine is an emerging approach for disease treatment based on disease endotypes, which are phenotypic subclasses associated with specific mechanisms underlying the disease. Although significant progress has been made in defining endotypes for asthma, definitions of endotypes for food and drug allergy or for anaphylaxis lag behind. Progress has been made in discovery of biomarkers to guide a precision medicine approach to treatment of food and drug allergy, but further validation and quantification of these biomarkers are needed to allow their translation into practice in the clinical management of allergic disease.
Cyclocybe dinggyensis R. L. Zhao & X. Y. Zhu 2023, sp. nov.
Creators: name: Zhu, Xin-Yu
name: Nyima, Tenzin
name: Vizzini, Alfredo
name: He, Mao-Qiang
name: Phurbu, Dorji
name: Zhao, Rui- Lin
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Agaricales
Strophariaceae
Cyclocybe
Cyclocybe dinggyensis

description: Cyclocybe dinggyensis R.L. Zhao & X.Y. Zhu sp. nov.
Fungal Names No: 571269
FoF number: 13982
Figs 3C, D, 5
Diagnosis. Basidioma slender. It differs from C. erebia in the number of spores, C. erebia is bisporic, C. dinggyensis is tetrasporic. It differs from C. erebioides in annulus, C. erebioides with a wide and complex membranous annulus, C. dinggyensis with a simple membranous annulus, and C. erebioides with clamp-connections, but C. dinggyensis clampless hyphae.
Etymology: the epithet “dinggye” refers to Dinggyê County where the type specimen is from.
Description. Basidiomes small. Pileus 20 mm in diam., broadly convex to convex, not distinctly depressed or umbo, hygrophanous, viscid, glabrous, brown to darker brown, generally darker in the center and almost brown in the margin, margin distinctly striate, not involute. Context thin, up to 1 mm, concolorous with pileus surface. Lamellae subdecurrent, thick, crowded, with series of 1–3 lamellulae, light brown. Stipe 43 × 4 mm, central, cylindrical, hollow, dry, fibrous, with annular zone, concolorous with pileus surface, daker at the base. Annulus single, concolorous with lamellae, membranous, persistent, upturned. Odor not distinctive. Taste indistinct.
Basidiospores 7.4–9.2 × 3.6–5.2 μm, [x = 8.4 ± 0.4 × 4.4 ± 0.4, Q = 1.7–2.2, Q m = 1.9 ± 0.1, n =20], oblong, subellipsoid to subamygdaliform,smooth, thick-walled, some oil-like droplets, no germ pore, brownish to brown in. Basidia 22.4–35.6 × 6.2–8.8 μm, clavate, 4-spored, most middle constrained, thin walled, hyaline. Pleurocystidia 46.7–59.7 × 9.2–13.0 μm, generally utriform, sometimes cylindrical, thin-walled, hyaline, numerous. Cheilocystidia 26.7–42.7 × 7.3–13.2 μm, similar to pleurocystidia but lacking cylindrical, mostly utriform, thin walled, hyaline. Hymenophoral trama subregular, consisting of 3.0–7.0 μm-wide hyphae. Pileipellis hymeniform formed by vesicular to clavate elements, 11.2–23.6 × 6.7–11.1 μm. Pileocystidia not observed. Caulocysidia not observed. Clamp-connections absent.
Habitat, ecology and distribution. Solitary on the ground, known from Tibet, China; from July to October.
Material examined. China. Tibet: Shigatse, Dinggyê county (27°55’15” N, 87°21’37” E), alt. 3060 m, 29 July 2022, collected by Mao-Qiang He, Bin Cao, Jia-Xin Li. ZRL20220414 (Holotype: HMAS 286979).
description: Published as part of Zhu, Xin-Yu, Nyima, Tenzin, Vizzini, Alfredo, He, Mao-Qiang, Phurbu, Dorji & Zhao, Rui- Lin, 2023, Two new species of Cyclocybe (Agaricales, Tubariaceae) from China, pp. 33-46 in Phytotaxa 620 (1) on pages 41-43, DOI: 10.11646/phytotaxa.620.1.3, http://zenodo.org/record/10015455
Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: We have measured fine airborne particles, 2.5 micrometers or less in diameter (PM2.5), in cannabis stores, cannabis festivals and other public events in the greater San Francisco Bay Area. By also recording behavior, measuring airborne nicotine and delta (9)-tetrahydrocannabinol (THC) and comparing to data from ambient air in nearby places where people are not consuming cannabis, we have documented cannabis PM2.5 concentrations that exceed 100 µg/m3 and even 1000 µg/m3.

 In the US, there are still ~50,000 preventable deaths each year among nonsmokers exposed to secondhand tobacco smoke. Cannabis smoke and tobacco smoke are physically and chemically similar and both contain chemicals known to be toxic and carcinogenic. Unlike active smoking, where the majority of deaths are from lung diseases, the majority of deaths from secondhand tobacco smoke exposure are from heart disease, primarily myocardial infarction. The human cardiovascular system is so sensitive to PM2.5 that increases as small as 10 µg/m3 in ambient PM2.5 are correlated with increases in cardiovascular mortality.

 Legalization of recreational and medical cannabis use in California has provided exceptions to the ban on use in public places and appears to have made public consumption a lower priority for law enforcement. This creates exposures for employees, event attendees and customers. The laws permitting cannabis consumption in public are explicit exceptions to smoke-free laws that have significantly reduced the harm from tobacco use. Smoke-free laws decrease the number of cigarettes people smoke and increase cessation, largely by de-normalizing smoking and exposure to smoke. From 1988 to 2018, exposure to nonsmoking US adults declined from 87.5% to 20.8% and the positive health effects were immense.

 We assert that studying the health effects of exposure secondhand cannabis aerosols is essential to formulating sound drug laws and protecting the public health. The experiments we propose include studying air quality and behavior in public places where people use cannabis, assessing exposure in nonsmokers, analyzing the chemistry of the cannabis aerosols we collect and generating controlled smoke samples in the laboratory. Together, they will help lay the groundwork for further research on the health effects of secondhand cannabis exposures.
Senna affinis H. S. Irwin & Barneby, Mem.
Creators: name: Silva, Lucas
name: Thomaz, Luciana Dias
name: Dutra, Valquíria Ferreira
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Senna
Senna affinis

description: 1.10 Senna affinis (Benth.) H.S. Irwin & Barneby, Mem. New York Bot. Gard. 35: 123. 1982.
Arbustos, ca 2,5 m alt.; ramos glabros, inermes. Estípulas não observadas, decíduas. Folhas paripinadas, 4-folioladas; pecíolos 30-33 mm compr., glabros; raque foliar 22-24 mm compr., glabra; folíolos 48-140 × 28-87 mm, elípticos, base oblíqua, ápice agudo, margem inteira, faces adaxial e abaxial glabras; nectários foliares entre os pares de folíolos, claviformes. Flores não observadas. Legumes ca. 22 × 0,9 cm, glabros, deiscentes. Sementes 130, reniformes a elípticas, 6-7 × 2-3 mm, pretas.
A espécie ocorre na Bolívia e no Brasil, nas regiões Nordeste (BA) e Sudeste (ES, MG, RJ) habitando os Domínios Fitogeográficos do Cerrado e da Mata Atlântica (BFG 2015, material suplementar). No PNMJ ocorre em vegetação Arbustiva Fechada Não Inundável, sendo este o seu primeiro registro de ocorrência para o Parque. Coletada com frutos em junho.
Senna affinis apresenta fácil identificação pelo seguinte conjunto de caracteres: nectários foliares claviformes entre os pares de folíolos, ramos quadrangulares em corte transversal e frutos longos (ca. 22 cm compr.).
Material examinado: BRASIL, ESPÍRITO SANTO, Vila Velha, Parque Natural Municipal de Jacarenema, 12.VI.2013, L. A. Silva 359 (VIES); 12.VI.2013, L. A. Silva 360 (VIES).
description: Published as part of Silva, Lucas, Thomaz, Luciana Dias & Dutra, Valquíria Ferreira, 2018, Leguminosae no Parque Natural Municipal de Jacarenema, Vila Velha, Espírito Santo, Brasil, pp. 261-289 in Iheringia, Série Botânica 73 (3) on page 272, DOI: 10.21826/2446-8231201873305, http://zenodo.org/record/10950818
Timia xanthaspis
Creators: name: El-Hawagry, Magdi S.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Ulidiidae
Timia
Timia xanthaspis

description: Timia xanthaspis (Loew, 1868)
Empyelocera xanthaspis Loew, 1868b: 175. Type unknown. Russia (Volgograd: Sarepta).
Distribution. PA: Egypt, Greece, Iran, Israel, Kazakhstan, South Russia, South Ukraine, Turkmenistan, Uzbekistan.
Egyptian localities. Sinai: Ein Gedeirat, Wadi Gedeirat. Dates of collection. April to May.
Genus ULIDIA Meigen
Ulidia Meigen, 1826: 385. Type species: Ulidia erythrophthalma Meigen, 1826: 387, by subsequent designation (Hennig 1940: 16).
description: Published as part of El-Hawagry, Magdi S., 2017, Catalogue of Egyptian Tephritoidea (Diptera: Schizophora: Acalyptratae), pp. 151-190 in Zootaxa 4299 (2) on pages 180-181, DOI: 10.11646/zootaxa.4299.2.1, http://zenodo.org/record/843233
Cannabidiol as a therapeutic approach for tobacco and nicotine cessation
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Tobacco/nicotine addiction remains a significant health concern for the individual and society. While medications are currently available to promote smoking cessation, they are largely ineffective in providing long-term abstinence for the majority of individuals desiring to quit tobacco/nicotine. Moreover, individuals that consume mentholated nicotine products often report more difficulty with cessation efforts. Thus, there is a critical need to develop novel therapeutic strategies to allow for a broader population to more effectively achieve long-term cessation. Pre-clinical research provides a unique opportunity to test therapeutic interventions in animals, which may then be applied in the clinical setting. In these studies, we will systematically examine whether cannabidiol (CBD) alters various aspects of nicotine dependence and whether the effectiveness of CBD is maintained with use of menthol-containing e-cigarette nicotine products. Together, findings from these studies will provide important evidence as to whether CBD is a promising and valid therapeutic approach for smoking cessation.
Senna appendiculata Wiersema
Creators: name: Silva, Lucas
name: Thomaz, Luciana Dias
name: Dutra, Valquíria Ferreira
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Senna
Senna appendiculata

description: 1.11 Senna appendiculata (Vogel) Wiersema, Taxon 38(4): 652. 1989.
(Fig. 4I)
Arbustos, ca. 2 m alt.; ramos glabros a esparso-puberulentos, inermes. Estípulas ca. 2 × 1cm, reniformes, livres, decíduas. Folhas paripinadas, 8-folioladas; pecíolos ca. 25 mm compr., esparso-puberulentos; raque foliar 65-80 mm compr., esparso-puberulenta; folíolos 40-70 × 30-51 mm, elípticos, base obtusa, ápice arredondado a obcordado, margem inteira, faces adaxial e abaxial glabras; nectários foliares presentes, entre os pares de folíolos, claviformes. Inflorescências racemosas, 7-13-floras, axilares. Flores assimétricas, pentâmeras, não ressupinadas; cálice dialissépalo, sépalas 17-20 × 8-10 mm, oblongas a elípticas, verdes a castanhas, glabras; corola dialipétala, pétalas 28-36 × 19-21 mm, elípticas, a oblongas, amarelas; estames 7, livres, 10-22 × 1,7-3 mm, heterodínamos; anteras dimórficas, 5-12 mm compr., poricidas, estaminódios 3; ovário ca. 27 × 1 mm, estipitado, puberulento; estilete 3-10- mm compr., glabro. Legumes 13-21 × 0,4 cm, glabros, deiscentes. Sementes 27-30, oblongas, 3-4 × 2,5 mm, castanhas a oliváceas.
Espécie de distribuição restrita ao território brasileiro, ocorrendo nas regiões Nordeste (AL, BA, PE, SE) e Sudeste (ES, SP). Habita os domínios fitogeográficos da Caatinga e da Mata Atlântica (BFG 2015, material suplementar). No PNMJ ocorre em vegetação Arbustiva Aberta Não Inundável. Coletada com flores em março, abril e junho e com frutos em junho.
Senna appendiculata possui como características diagnósticas: as estípulas reniformes, nectário foliares entre os pares de folíolos e flores com sete estames heterodínamos e anteras dimórficas.
Material examinado: BRASIL, ESPÍRITO SANTO: Parque Natural Municipal de Jacarenema: Vila Velha, 1.III.2012, L. A. Silva 102 (VIES); 28. VI.2012, L. A. Silva 161 (VIES); 28. VI.2012, L. A. Silva 162 (VIES); 28. VI.2012, L. A. Silva 163 (VIES); 28. VI.2012, L. A. Silva 164 (VIES); 1.IV.2012, L. A. Silva 217 (VIES).
description: Published as part of Silva, Lucas, Thomaz, Luciana Dias & Dutra, Valquíria Ferreira, 2018, Leguminosae no Parque Natural Municipal de Jacarenema, Vila Velha, Espírito Santo, Brasil, pp. 261-289 in Iheringia, Série Botânica 73 (3) on page 272, DOI: 10.21826/2446-8231201873305, http://zenodo.org/record/10950818
Inga edulis Mart.
Creators: name: Silva, Lucas
name: Thomaz, Luciana Dias
name: Dutra, Valquíria Ferreira
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Inga
Inga edulis

description: 2.1 Inga edulis Mart., Flora 20 (2, Beibl.): 113. 1837. (Fig. 4K)
Arbustos, ca. 3,5 m alt.; ramos puberulentos, lenticelados, inermes. Estípulas 4-5 × 0,9 mm, triangulares, livres, decíduas. Folhas paripinadas, 4-6-folioladas; pecíolos ca. 35 mm compr., alados, puberulentos; raque foliar 83- 63 mm compr.;, puberulenta; folíolos 108-140 × 31-43 mm, elípticos, base cuneada, ápice agudo, margem inteira, faces adaxial e abaxial esparso-puberulentas; nectários foliares entre os pares de folíolos, cupuliformes transversalmente comprimidos. Inflorescências capituliformes, ca. 18-floras, terminais. Flores actinomorfas, pentâmeras, não ressupinadas; cálice gamossépalo, pentâmero, 10 × 2,4 mm, tubuloso, verde-escuro, puberulento; corola gamopétala, ca. 17 × 3 mm, infundibuliforme, creme a verde; estames 35-40, monadelfos, 33-40 mm compr., homodínamos, tubo estaminal 15 mm compr.; filetes brancos; anteras uniformes, ca. 0,2 mm compr., rimosas; estaminódios ausentes; ovário ca. 45 mm compr., séssil, glabro; estilete 31-39 mm compr., glabro. Legumes nucoides 30-45 × 0,8 cm, glabros, indeiscentes. Sementes 40-50, elípticas, 3,5 × 2, pretas.
Espécie com distribuição Neotropical (Nunes et al. 2007). No Brasil ocorre nas regiões Norte (AC, AM, AP, PA, RO, RR), Nordeste (BA, PB, PE), Centro-Oeste (MT), Sudeste (ES, MG, RJ, SP) e Sul (PR, SC). Habita os Domínios Fitogeográficos da Amazônia, Caatinga, Cerrado e Mata Atlântica (BFG 2015, material suplementar). No PNMJ ocorre em Área Antropizada. Coletada com flores em janeiro e julho e frutos em janeiro.
Esta espécie teve apenas um indivíduo encontrado, localizado em um canteiro próximo ao posto do Polícia Rodoviária Federal, sendo provavelmente plantada. Difere das demais espécies pelos folíolos de 108-140 mm compr., nectários extraflorais cupuliformes transversalmente comprimidos e frutos com comprimento entre 30 e 45 cm, maiores que os presentes nas demais espécies. Este é o primeiro registro de ocorrência desta espécie para o PNMJ.
Material examinado: BRASIL, ESPÍRITO SANTO, Vila Velha, Parque Natural Municipal de Jacarenema, 25.VII.2012, L. A. Silva 233 (VIES); 10. I.2013, L. A. Silva s/nº (VIES).
description: Published as part of Silva, Lucas, Thomaz, Luciana Dias & Dutra, Valquíria Ferreira, 2018, Leguminosae no Parque Natural Municipal de Jacarenema, Vila Velha, Espírito Santo, Brasil, pp. 261-289 in Iheringia, Série Botânica 73 (3) on page 274, DOI: 10.21826/2446-8231201873305, http://zenodo.org/record/10950818
Search engine driven e-commerce surveillance of tobacco retailers
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: A successful Tobacco Control Endgame strategy in California will depend on timely and accurate surveillance of retail compliance with state/local sales restrictions. While the state and local health departments conduct routine surveillance of licensed brick-and-mortar tobacco retailers to monitor policy compliance, many retailers sell tobacco both at a brick-and-mortar store and with e-commerce (“brick-and-click” stores) or entirely through e-commerce (“click-only” stores). There is currently no state system for licensing online tobacco retailers or monitoring and enforcing their compliance to state/local sales restrictions. This could drive sales of restricted tobacco products to e-commerce in places where those restrictions are enforced in brick-and-mortar retailers. For example, although in-store surveillance suggests that San Francisco achieved high levels of compliance with its flavor restrictions, compliance among online retailers was not assessed and local consumers adapted to the restriction by obtaining tobacco (particularly vaping products) online. An e-commerce surveillance strategy is essential to modernize enforcement. We propose to monitor how tobacco retailers use search engines to market and sell flavored tobacco/vape products in restricted jurisdictions. Our approach will rely on collecting a lists of brick-and-click and click-only retailers (Aim 1), assessing retailer product offerings and delivery restriction practices, if any (Aim 2), and making attempts to purchase and send flavored tobacco products to addresses in jurisdictions that prohibit their sale (Aim 3). We will demonstrate the value of this approach through several research products that touch on multiple TRDRP research priorities (Priorities 1, 2, & 3). This includes assessing geographic disparities in online availability of flavored tobacco across California communities (Product 1); and identifying flavored hemp-derived cannabis products that are not regulated and may appeal to youth/young adults, e.g., JUUL-compatible flavored CBD pods (Product 2); reporting on compliance with local sales restrictions on flavored tobacco among online retailers (Product 3). We will disseminate the developed resources and study findings to policymakers, state and local health departments, and researchers to improve state/local enforcement strategies.
Harold G. Hoffman campaign song
Creators: name: Harker, Amos
Publisher: name: Harry Engel, Inc.
Year: 1939

description: This sheet music was printed in 1934 with a campaign song for Republican Harold G. Hoffman's gubernatorial bid in New Jersey.  The back cover of the document details Hoffman's South Amboy roots, his service in WWI, his rise in local and state politics, and further political goals.
Ulidia fascialis Hendel 1931
Creators: name: El-Hawagry, Magdi S.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Lonchaeidae
Ulidia
Ulidia fascialis

description: Ulidia fascialis Hendel, 1931
Ulidia fascialis Hendel, 1931a: 60. Holotype. Egypt (Mariout: Burg El-Arab) (EFC). Distribution. PA: Egypt.
Egyptian localities. Coastal Strip: Amria, Beheira, Burg El-Arab, Mariout. Lower Nile Valley: El-Hager (Giza). Western Desert: Wadi El-Natroun.
Plants from which flies were swept. Alfalfa (Medicago sativa L.), the true grasses (Poaceae) and Egyptian clover (Trifolium alexandrinum L.).
Dates of collection. February to August.
Remark. Morgulis & Freidberg (2014) noted that the original spelling of the species name is " fascialis " and the spelling " facialis " of Hennig (1940) and (Kameneva 2008) is an unjustified emendation.
description: Published as part of El-Hawagry, Magdi S., 2017, Catalogue of Egyptian Tephritoidea (Diptera: Schizophora: Acalyptratae), pp. 151-190 in Zootaxa 4299 (2) on page 181, DOI: 10.11646/zootaxa.4299.2.1, http://zenodo.org/record/843233
Coastal community vulnerability & resilience assessment pilot, Greenwich Township, Cumberland County, NJ, final report
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2011

description: Coastal Community Vulnerability Assessment Protocol (CCVAP) is a GIS-based methodology developed to assist land use planners, hazard mitigation planners, emergency managers, and other local decision-makers in the identification of their community’s vulnerability to coastal hazards and sea level rise. The basis of the vulnerability assessment relies upon the development of inundation maps. In order to determine where the most high hazard areas are within a community or the coastal zone as a whole, the New Jersey Coastal Management Office (NJCMO) developed a geospatial, composite overlay model, otherwise known as a coastal vulnerability index with six geospatial inputs. The NJCMO piloted the CCVAP in Greenwich Township, which validated the application of CCVAP and helped the NJCMO to understand the technical assistance needs of rural, coastal communities in the state.
Tobacco Treatment Engagement and Implementation in a Community Setting
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Research consistently indicates that lower socioeconomic status (SES) individuals smoke at higher rates compared to the general population. In addition, lower SES tobacco users have a higher prevalence of substance use disorders and mental health comorbidities. Despite awareness of high rates of tobacco use, enrollment/engagement and treatment of tobacco users remains low for this population. Neighborhood Health is a non-profit 501(C) community health organization and a Federally Qualified Health Center (FQHC) that serves 59,694 patients (with 5767 smokers) of which over 72% are Medi-Cal beneficiaries. Being a FQHC facility, this is an ideal place to provide healthcare for lower SES tobacco users. Given the collaborative practice approach with clinical pharmacist providers (CPP) with a scope of practice, neighborhood health is an ideal environment to establish a community-based tobacco treatment clinic. The objective of the proposed Community-Partnered Participatory Research Award (CPPRA) project is to implement a standardized screening, referral and treatment model in a community setting at Neighborhood Health for lower SES tobacco users. This pilot includes the following components: 1) implement a Brief Telephone Treatment Engagement Counseling (TTE) protocol to increase utilization of evidence-based treatment 2) establish an intensive pharmacist managed telephone tobacco treatment program that can provide evidenced-based pharmacotherapy and behavioral counseling. Primary goal is to explore tobacco cessation outcomes to see if a telephone engagement protocol can increase patients' acceptance of medications and counseling.
Thyone fusus
Creators: name: Arumugam-Moonilal, Preyan
name: Thandar, Ahmed S.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Echinodermata
Holothuroidea
Dendrochirotida
Thyonidae
Thyone
Thyone fusus

description: Thyone fusus (Müller, 1776)
(Figure 1A–F)
Holothuria fusus O.F. Müller, 1776: 232, pl. 10, figs. 5–6.
Thyone fusus Madsen, 1941: 17, text-figs. 12–16; Madsen & Hansen, 1994: 40, fig. 5, 23–24, map 10; McKenzie, 1991: 136 (synonymy).
Thyone flexus Hodge, 1867: 44, pl. 10, fig. 2–11.
Diagnosis (from Madsen & Hansen 1994, McKenzie 1991, amended herein)
Medium-sized species, reaching about 70 mm in length (an exceptional figure of 200 mm was reported by Mortensen (1927) but this needs verification). Body fusiform to spindle-shaped, tapering posteriorly. Colour in life greyish-white to light brown to fawn, brown in alcohol. Tube feet well developed, distributed over entire body, numerous ventrally, scattered dorsally, often with adhering sand grains or other debris.Anal teeth present. Calcareous ring long, tubular, both ring and processes sub-divided; radial plates deeply notched anteriorly, dorsal radial plates extended posteriorly before bifurcating beyond posterior border of interradial plates, posterior processes of radial plates long; interradials prolonged, two ventral ones slightly longer. Deposits of body wall 2-pillared tables, disc with four primary holes and often a few additional, smaller, peripheral holes around the primary ones; spire of moderate height, ending in inconspicuous teeth. Supporting tables of tube feet with curved disc and endplate, the latter delicate in smaller individuals. Tentacle deposits perforated rods and plates. Introvert supported by rosettes and tables with multilocular disc and a spire with or without a cross-bar..
Material examined: Four specimens, identified as T. fusus, originating from the type locality, were received on loan from the Natural History Museum, Oslo, Norway. The largest specimen was selected for dissection and ossicle study and is here designated as the neotype, while the other three were only studied for their body wall ossicles. The current material corresponds well with the descriptions of the species presented by especially Madsen (1941), Mckenzie (1991) and Madsen & Hansen (1994).
description: Published as part of Arumugam-Moonilal, Preyan & Thandar, Ahmed S., 2023, Designation of a neotype for the dendrochirotid holothuroid, Thyone fusus (Müller) (Echinodermata: Holothuroidea: Dendrochirotida: Thyonidae), pp. 585-590 in Zootaxa 5369 (4) on page 587, DOI: 10.11646/zootaxa.5369.4.7, http://zenodo.org/record/10149942
Maternal E-cigarette vaping increases risk of ischemic brain injury in newborns
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Since its introduction into the U.S. market nearly a decade ago, the use of electronic cigarettes (E-cig) vaping has increased rapidly. Even more concerning, the use of E-cig among youth and young pregnant women is much higher than conventional cig use. E-cig use and abuse in pregnant women has become an increasing health concern in the 21st century. There is an urgent need for understanding the short, as well as long-term health effects of E-cig on fetal development. Neonatal stroke is among the top 10 causes of death in children. It is well known that tobacco smoking during pregnancy is one of the worst risk factors for the setting of stroke in newborns. However, there is still a lack of data on whether and how E-cig using during pregnancy increases the risk of brain ischemic disease in offspring. Our current goal is to fill this gap and provide evidence that whether and how E-cig use during pregnancy affects the unborn baby’s brain development, leading to the increased risk of stroke in newborns. To accomplish our goal, we will set up an e-cig exposed pregnant rat model to mimic human E-cig vaping. Then we will use this animal model to test a central hypothesis that E-cig use during pregnancy will increase the risk of stroke in newborns by altering some specific markers in the unborn baby brain tissues. Once our goal is achieved, this project will have important public health impacts. It will provide new proof of the adverse effects of E-cig use by mothers on the unborn baby brain. It will also help to find the cause of stroke in newborns related to E-cig use. Our findings may suggest new therapeutic targets in the prevention and treatment of the E-cig-induced fetal origins of stroke in newborns.
Ulidia wadicola Steyskal 1968
Creators: name: El-Hawagry, Magdi S.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Lonchaeidae
Ulidia
Ulidia wadicola

description: Ulidia wadicola Steyskal, 1968
Ulidia wadicola Steyskal, 1968: 125. Holotype. Egypt (northern Galala (east of El Saff): Wadi Wirak) (EFC); paratypes. Same data as holotype (USNM). See: Kameneva (2008).
Distribution. PA: Egypt.
Egyptian localities. Eastern Desert: northern Galala, Wadi Wirak.
Dates of collection. April.
description: Published as part of El-Hawagry, Magdi S., 2017, Catalogue of Egyptian Tephritoidea (Diptera: Schizophora: Acalyptratae), pp. 151-190 in Zootaxa 4299 (2) on page 181, DOI: 10.11646/zootaxa.4299.2.1, http://zenodo.org/record/843233
Eupyrochroa Blair 1914
Creators: name: Gao, Qi
name: Young, Daniel K.
name: Zhan, Zhi-Hong
name: Cheng, Hai-Yun
name: Pan, Zhao
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Pyrochroidae
Eupyrochroa

description: Genus Eupyrochroa Blair, 1914
Eupyrochroa Blair, 1914: 316. Type species: Pyrochroa insignita Fairmaire, 1894, by subsequent designation (Pollock & Young 2008: 49).
Diagnosis. Adults of Eupyrochroa are most similar to those of Pyrochroa spp. but can be easily distinguished by the larger body size, the head with strongly produced genae (Fig. 3A–C) (genae rounded in Pyrochroa spp.), and lateral aspects of the pronotum strongly angulate sub-basally (Fig.1 A–F) (rounded in Pyrochroa spp.). However, these two genera do not exhibit distinct differences in several features (e.g., the coloration of the head, pronotum, and scutellum, and structure of the male genitalia) (see Discussion, below).
After comparison with the larval descriptions of the three Pyrochroa species from Europe (Molfini et al. 2021, 2022), the larva of Eupyrochroa is similar to that of Pyrochroa. The lateral lobes of urogomphal plate are well-developed, rounded, the urogomphal plate possesses lateral teeth on the outside and two urogomphal pits, the urogomphi long, slender, straight, and subparallel, a weakly developed parabasal ridge is associated with abdominal terga I and VIII. Unlike Pyrochroa larvae (Molfini et al. 2022), the urogomphal plate of E. insignita is also toothed on the inside.
Distribution. China, Laos (New Country Record, see Other materials, below).
description: Published as part of Gao, Qi, Young, Daniel K., Zhan, Zhi-Hong, Cheng, Hai-Yun & Pan, Zhao, 2024, Revision of Eupyrochroa Blair, 1914 (Coleoptera: Pyrochroidae) based on morphological comparison and molecular phylogenetics, pp. 238-252 in Zootaxa 5406 (2) on page 243, DOI: 10.11646/zootaxa.5406.2.2, http://zenodo.org/record/10618144
Elucidating Mechanisms of E-cigarette Mediated Vascular Dysfunction with Human iPSCs
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Despite decades of declining tobacco use, e-cigarettes are now becoming popular amongst youth in the United States and replacing traditional cigarette smoking. The emergence of e-cigarette or vaping use-associated lung injury has revealed significant lung toxicity due to e-cigarettes, and e-cigarettes are expected to have adverse effects on the cardiovascular system as well. However, the long-term consequences of e-cigarette usage may take years to manifest in population studies. Traditional cigarettes cause abnormal function in the cells lining the blood vessels, while the effects of e-cigarettes on vascular cells and the corresponding mechanisms are unknown. Recent studies have identified ALDH2*2 gene variant as one of the high-risk which cause vascular diseases in smokers. I hypothesize that e-cigarettes, like traditional cigarettes, can similarly cause vascular dysfunction via inflammation, and that the ALDH2*2 variant will further exacerbate these effects, leading to greater risk of vascular diseases. In this study, I will utilize both human induced pluripotent stem cells (iPSCs) and traditional mice studies to investigate the mechanisms of e-cigarette toxicity on the cardiovascular system in individuals carrying the ALDH2*2 variant. I will rigorously investigate the pathways and genes involved in iPSC-derived vascular cells and in an ALDH2*2 mouse model. The outcomes of this research will provide insights into the molecular mechanisms and signals for individuals at high risk for cardiovascular disease due to traditional and e-cigarette smoking. Furthermore, this proposed research project will offer a proof-of-principle of using iPSC-based approaches to help identify avenues for cardiovascular disease therapies in the emerging e-cigarette crisis.