cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Press water from the mechanical drying of Douglas-fir wood chips has multiple beneficial effects on lignocellulolytic fungi
Creators: name: Reppke, Manfred J.
name: Gerstner, Rebecca
name: Windeisen-Holzhauser, Elisabeth
name: Richter, Klaus
name: Benz, J. Philipp
Publisher: name: figshare
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1: Figure S1. Physico-chemical analysis of press water from Douglas-fir with bark (PWB). a Concentration of macro solids, micro solids and dissolved substances. b Mass percentage of hydrolysate, acid soluble aromatics, and acid insoluble residues of PWB solids after acid hydrolysis. Figure S2. Endoglucanase and endoxylanase activities of T. reesei RUT-C30 culture supernatants in the presence of increasing PW (% v/v) concentrations. Cultivation in MA medium with 1% Avicel at 30 °C and 250 rpm. Significant differences (p > 0.05) relative to the control are indicated by asterisks. Figure S3. Absorbance scan of the culture supernatants of G. applanatum, T. versicolor, and P. chrysosporium cultivated in 50% PW with potato dextrose yeast medium (PDY) in shaking flasks with 30 mL medium, at 100 rpm (50 mm throw), 28 °C. Absorbance in the range of 230–800 nm was measured in UV transparent cuvettes. Error bars indicate the standard deviation of biological triplicates. The control was not measured in replicates. Figure S4. Photograph of the culture supernatants of G. applanatum, T. versicolor, and P. chrysosporium cultivated in 50% PW with potato dextrose yeast medium (PDY) in shaking flasks with 30 mL medium, at 100 rpm (50 mm throw), 28 °C. Figure S5. Chromatogram of the GC/MS of the hydrophobic fraction of dissolved substances in the PW, concentrated with a C18ec SPE cartridge. Chemical formulas for 3-(4-Hydroxyphenyl)-1-propanol and taxifolin are showed. N.i., not identified. Table S1. Ion concentration in PW Douglas-fir with bark relative to Mandels-Andreotti medium (MA). Table S2. Compositional analysis of Douglas-fir wood chips (pressed and unpressed) expressed in % of the total weight. Table S3. Concentration of dissolved sugars in Douglas-fir PW with bark measured in a HPAEC-PAD.
The University VP Diptych
Creators: name: Lenardic, Adrian
Publisher: name: Zenodo
Year: 2024

description: This is a collection of two Op-Eds that appeared in Future U Forum. Both are about changes in how Universities run and function. That affects scientific research done at Universities, as well as higher education in general (science education being a more specific component). If your interests are about specific science topics, then the collection may not be for you. If you are interested in how universities, where science is done, are being restructured, then the collection may be of interest. It might also hold some interest if you are thinking about an academic career path.
Supplementary document for Photochromic engineering of radiative decay rate in plasmon-emitter coupling - 6356003.pdf
Creators: name: Baudrion, Anne-Laure
name: aruldoss, Reegan
name: Gerard, Davy
name: Adam, Pierre-Michel
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary informations
Index of Publications. The Bovine Practitioner 1980-1984 / Proceedings of the Annual Meetings 1980-1984
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2019

description: Author and Subject indexes for the Bovine Practitioner and the Proceedings of the Annual Meetings, 1980-1984.
description: The Bovine Practitioner, Bovine Practitioner. Indexes.
AGE-RAGE AXIS: IMPLICATION IN FIBROSIS AND AGING
Creators: name: BOULANGER, Eric
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Glycation is a major mechanism of aging. AGEs (Advanced Glycation End-products) are formed and accumulate during diabetes, renal failure, inflammation and aging (endogenous AGEs). AGEs are also formed during high temperature sterilization and cooking (exogenous AGEs).
The human health effects of dietary AGEs are underestimated.
AGEs are irreversibly formed through the Maillard reaction, resulting from the binding of a sugar to a protein. AGEs exert their toxicity through 3 main mechanisms: in situ glycation, AGE deposits and interaction with the receptor for AGE (RAGE).
In our group, we demonstrate that dietary CML (CarboxyMethylLysin), AGE with the highest affinity for RAGE, accelerates vascular and renal aging in a RAGE-dependent manner.
1/ CML-enriched diet is followed by increased arterial stiffness and wall thickness, elastin fiber disruption and decreased expression of SIRT1, a marker of aging.
2/ Dietary CML predominantly accumulates in kidney. CML-enriched diet was followed by a significant accelerated glomerulosclerosis.
RAGEnull animals were protected from vascular and renal alterations induced by a CML-enriched diet.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
Bovine Practitioner Vol. 53, No. 2 (2019 Summer). Front matter
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2019

description: Cover, Masthead, Table of Contents, and other editorial information.
description: The Bovine Practitioner, Vol. 53, No. 2 (2019 Summer)
Additional file 1 of Impact of pitavastatin on new-onset diabetes mellitus compared to atorvastatin and rosuvastatin: a distributed network analysis of 10 real-world databases
Creators: name: Seo, Won-Woo
name: Seo, Seung In
name: Kim, Yerim
name: Yoo, Jong Jin
name: Shin, Woon Geon
name: Kim, Jinseob
name: You, Seng Chan
name: Park, Rae Woong
name: Park, Young Min
name: Kim, Kyung-Jin
name: Rhee, Sang Youl
name: Park, Meeyoung
name: Jin, Eun-Sun
name: Kim, Sung Eun
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1: Table S1. Baseline characteristics of patients with pitavastatin vs. atorvastatin or rosuvastatin in KHNMC cohort. Table S2. Baseline characteristics of patients with pitavastatin vs. atorvastatin or rosuvastatin in WKUH cohort. Table S3. Baseline characteristics of patients with pitavastatin vs. atorvastatin or rosuvastatin in DCMC cohort. Table S4. Baseline characteristics of patients with pitavastatin vs. atorvastatin or rosuvastatin in AUMC cohort. Table S5. Baseline characteristics of patients with pitavastatin vs. atorvastatin or rosuvastatin in PNUH cohort. Table S6. Baseline characteristics of patients with pitavastatin vs. atorvastatin or rosuvastatin in EUMC cohort. Table S7. Baseline characteristics of patients with pitavastatin vs. atorvastatin or rosuvastatin in NHIMC cohort. Table S8. Baseline characteristics of patients with pitavastatin vs. atorvastatin or rosuvastatin in MJH cohort. Table S9. Baseline characteristics of patients with pitavastatin vs. atorvastatin or rosuvastatin in KWMC cohort.
AABP Conference (2018): Minutes of the American Association of Bovine Practitioners Annual Business Luncheon
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2019
Subjects: American Association of Bovine Practitioners
congresses

description: The Bovine Practitioner, Vol. 53, No. 1 (2019 Spring)
METABOLIZATION OF MAILLARD REACTION PRODUCTS BY THE HUMAN COLONIC MICROBIOTA
Creators: name: HELLWIG, Michael
name: BUNZE, Diana
name: HUCH, Melanie
name: FRANZ, Charles M.A.P.
name: HENLE, Thomas
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Objectives: Heat-treatment of foods leads to glycation of individual protein-bound amino acids such as lysine and arginine. Substantial amounts of up to 1000 mg of Amadori compounds (mainly fructoselysine) and up to 75 mg of advanced glycation end products (AGEs, mainly pyrraline and carboxymethyllysine) are ingested with the daily diet [4]. The majority of these products cannot pass the intestinal barrier and enter into circulation and could therefore serve as a substrate for bacterial fermentation [2]. Degradation of fructoselysine has already been shown in rat feces cultures [1].
Methodology: Four MRPs (fructoselysine, carboxymethyllysine, pyrraline, maltosine) were synthesized and anaerobically incubated in the presence of fecal suspensions from 8 human volunteers at 37 °C for up to 72 h. The stability of the compounds was analyzed by HPLC-MS/MS (fructoselysine, CML) or HPLC-UV (pyrraline, maltosine) [3].
Results: Fructoselysine was degraded nearly completely in the presence of fecal suspensions of all subjects during 4 h, whereas maltosine proved to be completely stable. Pyrraline was degraded by 25-40% in 72 h by the gut microbiota of all subjects. Strong inter-individual differences in the kinetic and extent of degradation appeared when CML was incubated. However, no metabolites (e.g., biogenic amines) could as yet be identified. Conclusions: The human large intestinal microbiota is able to degrade individual MRPs. Especially Amadori products such as fructoselysine, which are ingested in comparatively high amounts, can thus possibly have an influence on the composition and viability of the gut microbiota. Further studies will focus on identification of the degrading species and in-depth metabolite analysis.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
STRESS-STRAIN STATE OF AN ANNULAR PLATE
Creators: name: Nguyen Dang Khoa
name: Nguyen Minh Hue
Publisher: name: Zenodo
Year: 2025

description: An axisymmetric plane stress state of a compressible, ideally elastic-plastic body is considered. The material is assumed to exhibit both elastic and plastic behavior under loading. The analysis focuses on the mechanical response of the body under these conditions.
AGE-RAGE INTERACTION IN FIBROSIS OF THE EYE LENS
Creators: name: NAGARAJ, Ram
name: SMUDA, Mareen
name: SMITH, Andrew J. O
name: GLOMB, Marcus A
name: WORMSTONE, I. Michael
name: RAGHAVAN, Cibin T
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Due to low turnover rate basement membrane (BM) proteins accumulate chemical modifications with age. Glycation is one such modification, which leads to the formation of advanced glycation endproducts (AGEs). The eye lens capsule is a BM secreted by lens epithelial cells. We have found age-dependent increases in AGE levels in the human lens capsule and significantly higher levels in cataractous lens capsules. We also found that AGEs in the human lens capsule promoted the TGFβ2-mediated epithelial-to-mesenchymal transition (EMT) of lens epithelial cells, and the AGE content of the capsule proteins was correlated to the synthesis of TGFβ2- mediated α-smooth muscle actin, which we proposed as a mechanism for posterior capsule opacification (PCO) or secondary cataract formation. We then investigated the role of a receptor for AGEs (RAGE) in the TGFβ2- mediated EMT in a human lens epithelial cell line. The RAGE levels were unaltered in cells cultured on either native or AGE-modified BM or upon treatment with TGFβ2. RAGE overexpression significantly enhanced the TGFβ2-mediated EMT responses in cells cultured on AGE-modified BM compared with the unmodified matrix. In contrast, treatment of cells with a RAGE antibody resulted in a significant reduction in the TGFβ2-mediated EMT response. This was accompanied by a reduction in TGFβ2-mediated Smad signaling. Our latest work showed that N     enhances the TGFβ2-mediated EMT response lens epithelial cells. Together these results suggested that the interaction of matrix AGEs, possibly CML, with RAGE plays a role in the TGFβ2-mediated EMT of lens epithelial cells and suggest that the blockade of RAGE could be a strategy to prevent PCO and other age-related fibrosis.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
Additional file 1 of Issues related to velocity structure estimation in small coastal sedimentary plains: case of Tottori plain facing the Sea of Japan
Creators: name: Kagawa, Takao
name: Noguchi, Tatsuya
Publisher: name: figshare
Year: 2022
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Detailed parameters of the most suitable solution in Fig. 3c, d. Table S2. Detailed parameters to calculate site amplifications in Fig. 5a–c.
Supplementary document for THz optical beat-note detection with a fast hot electron bolometer operating up to 31 GHz - 6356112.pdf
Creators: name: Torrioli, Guido
name: Forrer, Andres
name: Beck, Mattias
name: Carelli, Pasquale
name: Chiarello, Fabio
name: Faist, Jérôme
name: Gaggero, Alessandro
name: Giovine, Ennio
name: Martini, Francesco
name: Senica, Urban
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental material
Bovine Practitioner Vol. 53, No. 1 (2019 Spring). Frontmatter
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2019

description: Cover, Masthead, Table of Contents, and other editorial information.
description: The Bovine Practitioner, Vol. 53, No. 1 (2019 Spring)
CONCEPTS AND MISCONCEPTS REGARDING THE NATURE OF THE OXYGEN FREE-RADICALS IN THE LIVING SYSTEMS
Creators: name: ZS.-NAGY, Imre
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: This lecture will survey the history of the free-radical research in biological systems starting from the original concept of D.
Harman formed during the late fifties. This original concept has undergone a series of misinterpretations during the subsequent decades, leading to a number of contradictions in the theory and the applications if this idea in biology and medicine. At last a tentative explanation will be presented on the basis of the real physicochemical properties of the oxygen free-radicals and the macromolecules involved in the biological functions.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
Bovine Practitioner Vol. 52, No. 2 (Summer 2018). Front matter
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2018
Subjects: cows

description: Cover, Masthead, Table of Contents, and other editorial information.
description: The Bovine Practitioner, Vol. 52, No. 2 (2018 Summer)
POLY(ADP-RIBOSE) SIGNALISE IN OXIDATIVE STRESS
Creators: name: VIRAG, László
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Poly-ADP-ribosylation is an NAD-dependent protein modification reaction. In various oxidative stress-related paradigms DNA breaks activate poly(ADP-ribose) polymerase (PARP) enzymes which in turn modify target proteins with NAD-derived (ADP-ribose)n polymers. This reversible protein modification (PARylation) regulates transcription, kinase cascades, metabolism, differentiation, autophagy, cell death only to name a few cell functions and fates. Moreover, it leads to diverse biological outcomes with wide ranging implications for diseases as diverse as diabetes, inflammation, ischemia-reperfusion injury and cancer.
Pathways leading to the formation of advanced glycation endproducts (AGEs) as well as cellular effects of AGEs are accompanied by overproduction of reactive oxygen and nitrogen species and as such may be intertwined with PARylation-related pathologies. The lecture aims to highlight proven and possible interactions between the oxidative stress-induced PARylation events and AGE-related pathologies.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
Bovine Practitioner Vol. 52, No. 1 (2018 Spring). Frontmatter
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2018

description: Cover, Masthead, Table of Contents, and other editorial information.
description: The Bovine Practitioner, Vol. 52, No. 1 (2018 Spring)
CONTROLLING ROS IN PLATINUM-INDUCED PERIPHERAL NEUROPATHY: THERAPEUTIC APPLICATIONS
Creators: name: CERLES, Oliver
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Platinum-based chemotherapies, while being efficient at preventing tumor growth, display several types of toxicities many of which present as neurological impairments. Oxaliplatin indicated in cancers of the colon, stomach and ovaries induces two forms of peripheral neuropathies, namely acute and chronic. While the acute form translates as transitory cold hyperalgesia which resolves within hours to days following first infusion, the chronic form resulting from cumulative high doses translates as irreversible paresthesia and cold hypoesthesia which represent a limiting-factor for its use in therapeutics. Oxaliplatin anti-tumor efficacy has been linked to ROS-induced apoptosis of tumor cells through GSH depletion. ROS being ubiquitously toxic, neuronal cells exposed degenerate upon administration of oxaliplatin. Relying on differential basal cell-specific GSH production while modulating pro-inflammatory pathways activated by these ROS may be beneficial in addressing neurodegenerative processes in patients suffering from oxaliplatin-induced peripheral neuropathies.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
O USO DO GOOGLE CLASSROOM COMO AMBIENTE VIRTUAL DE APRENDIZAGEM
Creators: name: Araújo Lima, Danielli
name: Silva, Eduardo Cassiano da
name: Menezes, Felipe Augusto de
Publisher: name: figshare
Year: 2022
Subjects: subject: 130313 Teacher Education and Professional Development of Educators
subject: FOS: Educational sciences

description: À medida que novas tecnologias vêm sendo desenvolvidas, abrangendo e
 manipulando novas idéias, os conceitos de educação on-line estão mudando
 rapidamente. Em resposta à essas mudanças, muitos estados, instituições e
 organizações têm trabalhado em planos estratégicos para implementar ambientes virtuais
 de aprendizagem (AVAs). Ao mesmo tempo, equívocos e mitos relacionados à dificuldade
 de ensino e aprendizagem são relatados, principalmente relacionados ao apoio e
 compensação necessários para instrutores e estudantes. Este documento fornece uma
 discussão inicial sobre o uso do Google Classroom como um aplicativo didático-
 pedagógico que favorece a comunicação entre alunos e professores durante as aulas dos
 cursos da área de Informática do Instituto Federal do Triângulo Mineiro durante o período
 de dois meses do primeiro semestre de 2017. Os resultados indicaram que a maioria dos
 alunos passaram a interagir mais com o professor e também houve uma melhoria na
 pontualidade de entrega dos trabalhos. Adicionalmente os alunos ficam em imersão com a
 disciplina, uma vez que, eles são alertados por celular a cada notificação realizada pelo
 professor. Os resultados apontam que, embora existam desvantagens em relação ao uso
 do aplicativo em sala de aula, devido à ausência de alguns recursos importantes, as
 vantagens são extremamente positivas no contexto educacional
Supplementary document for Flexible optical fiber channel modeling based on neural network module - 6356438.pdf
Creators: name: Jiang, Rui
name: Wang, Zhi
name: Jia, Tao
name: Fu, Ziling
name: Chao, Shang
name: Wu, Chongqing
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Bovine Practitioner Vol. 51, No. 2 (Summer 2017). Front matter
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2017

description: Cover, masthead, table of contents, and other editorial information.
description: The Bovine Practitioner, Vol. 51, No. 2 (2017 Summer)
ANTIOXIDANT SYSTEMS IN BRAIN ASTROCYTES: SOURCES OF CYSTEINE FOR GLUTATHIONE
Creators: name: MCBEAN, Gethin
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Astrocytes supply neurons with the antioxidant, glutathione. Cysteine is the precursor of glutathione and is imported as cystine via the plasma-membrane cystine glutamate exchanger. Recent evidence has shown that the transsulphuration pathway that converts methionine to cysteine also contributes to glutathione in astrocytes. Data on the relationship between the cystine glutamate exchanger and the transsulphuration pathway and changes in response to oxidative stress in astrocytes will be presented. The implications of this work for targeting pathways of cysteine metabolism in neurodegenerative disease will be discussed.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
ACUTE, CHRONIC LUNG DISEASES AND OXIDATIVE STRESS:TARGETING RESPIRATORY INFECTIONS, COPD AND VIRAL-INDUCED EXACERBATIONS OF COPD
Creators: name: VLAHOS, Ross
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Introduction: Reactive oxygen species (ROS) are a family of highly reactive molecules that are produced by a variety of cell types in the lung in response to chemical and physical agents in the environment. It is well known that ROS are critical in host defence as they kill invading pathogens, but that their excessive accumulation in the lung results in oxidative damage. Oxidative stress, which is defined as the persistent overproduction of ROS that overwhelms endogenous antioxidant defence systems, has been implicated in both acute (e.g respiratory virus infections) and chronic (e.g. COPD) lung diseases. Therefore, targeting oxidative stress may be a novel way to treat these lung diseases.

Results: We have shown that targeting oxidative stress with the Nox2 oxidase inhibitors and ROS scavengers, apocynin and ebselen could ameliorate influenza A virus (IAV)-induced lung inflammation and pathology, cigarette smoke-induced lung inflammation, acute exacerbations of COPD (AECOPD) and skeletal muscle wasting in mice.

Conclusion: Targeting oxidative stress may be a novel strategy to treat both acute and chronic lung diseases.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Bovine Practitioner Vol. 51, No. 1 (Spring 2017). Front matter
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2017

description: Cover, Masthead, Table of Contents, and other editorial information.
description: The Bovine Practitioner, Vol. 51, No. 1 (2017 Spring)
Get the brain animated!
Creators: name: Athanasia Monika Mowinckel
Publisher: name: Zenodo
Year: 2018
Subjects: Packages
Neuroimaging
R

description: Dr. Mowinckel's blog:   I'm super delighted that our ggseg package was so well received! We almost immediately got it on [Neuroconductor](https://neuroconductor.org/), which is a neuroimaging equivalent to Bioconductor. We got some pull requests from people helping us improve the code, and particularly get it ready for CRAN when we decide to submit it there.
REACTIVE OXYGEN-RELATED DISEASES: THERAPEUTIC TARGETS AND EMERGING CLINICAL INDICATIONS
Creators: name: SCHMIDT, Harald
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Numerous diseases and disease models have been suggested to be associated with oxidative stress; however very few if any have resulted in clinical application; some trials have been giant failures. Two innovations may provide a more successful and evidence-based way forward: the therapeutic move from focussing on ROS to their enzymatic sources and targets and the differentiation of physiological and pathological functions of these. Moreover a cluster of disease phenotypes within the so-called ‘diseasesome’ seems specifically linked to ROS- mediate pathologies.
Here we present examples for such target validation within this cluster in diabetic end-organ damage and stroke, both linked by shared common redox mechanisms.
These therapeutic advances will be backed-up by precision diagnostics that enable early detection, patient stratification, detecting target engagement and therapeutic monitoring.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Bovine Practitioner Vol. 50, No. 2 (2016 Summer). Front matter
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2016

description: Cover, Masthead, Table of Contents, and other editorial information.
description: The Bovine Practitioner, Vol. 50, No. 2 (2016 Summer)
Bovine Practitioner Vol. 48, No. 1 (2014 Spring). Front matter
Creators: name: American Association Of Bovine Practioners,
Publisher: name: The Bovine Practitioner
Year: 2013

description: Cover, masthead, table of contents, and other editorial information.
description: The Bovine Practitioner, Vol. 48, No. 1 (2014 Spring)
title: Press Release: Reston Land Corporation, "Mobil Land Development (Virginia) Coporation Takes Title to 1219 Loudoun County Acres," February 3, 1989
Creators: name: Reston Land Corporation
Publisher: name: George Mason University
Year: 2006
Subjects: subject: Reston (Va.)
subject: Dulles Toll Road
subject: Loudoun County (VA)

description: Textual: Press Release; staple holes and hole punched, 11" x 8.5" (29.7 cm x 21.6 cm)
description: Press release from Reston Land Corporation from February 3, 1989 entitled "Mobil Land Development (Virginia) Corporation Takes Title to 1219 Loudoun County Acres." This release concerns Mobil Land Development (Virginia) purchase of 1,219 acres in Loudoun County, VA. The northeast portion of this property was in one mile of the extension of the Dulles Toll Road. This is the first piece of property purchased by Mobil Land Development (Virginia) since the corporation took over development and ownership of Reston and Colonial Village/Place in Arlington. Planned Community Archives Collection, 456.01
title: Cup: "We Believe" ca. 2006
Creators: name: University, George Mason
Publisher: name: George Mason University
Year: 2006
Subjects: subject: George Mason University
subject: Basketball

description: Cup: color, 3.7" x 4.5" (9.4 cm x 11.4 cm)
description: Plastic cup distributed by Mason Dining Services with drink purchase during the NCAA tournament. 2005-06 Men's Basketball Season and Tournament Run Collection Box 3
Bovine Practitioner Vol. 47, No. 2 (Summer 2013). Front Matter
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2013

description: Cover, Masthead, Table of Contents, and other editorial information.
description: The Bovine Practitioner, Vol. 47, No. 2 (2013 Summer)
PRE-CLINICAL EVIDENCES THAT ANTIOXIDANT SUPPLEMENTATION CORRECTS SPERM DNA OXIDATIVE DAMAGE AND IMPROVES REPRODUCTIVE SUCCESS
Creators: name: DREVET, Joël R
name: AITKEN, R. John
name: GUTIEREZ-ADAN, Alfonso
name: GHARAGOZLOO, Parviz
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Gamete nuclear integrity is the most critical parameter to ensure complete and harmonious embryonic development. It is also a major contributor to the health and wellbeing of the progeny. The most frequent sperm DNA alteration in natural as well as in assisted reproduction involves an oxidative attack, leading to the formation of oxidized base adducts such as 8-hydroxy-2'-deoxyguanosine. Oxidative alterations of the paternal genome that are not efficiently repaired by the oocyte or not compensated by the maternal genome emphasize the risk of trans-generational effects that may be increased when fertilization involves such spermatozoa showing high oxidative DNA damage. It may partly explain the low efficacy of assisted reproductive technologies. We will show here that oral antioxidant supplementation using a well-designed formulation significantly reduces sperm DNA damage (SDD) in GPX-5 knockout mice and restores pregnancy rates almost back to normal levels in mice subjected to Scrotal Heat Stress (SHS).
These results, if confirmed in humans, might impact clinical fertility practice since current clinical studies confirm moderate to severe SDD in about 60% of all men visiting IVF centers and in about 80% of men diagnosed with idiopathic male infertility, figures which are gravely concerning.
Antioxidant supplementation could be an adjuvant therapy prior to undertaking ART procedures to improve fertilization rates, maintain a healthy pregnancy, and reduce de novo sporadic mutations being passed onto children.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Bovine Practitioner Vol. 49, No. 2 (2015 Summer). Front matter
Creators: name: American Association Of Bovine Practioners,
Publisher: name: The Bovine Practitioner
Year: 2015

description: Cover, masthead, table of contents, and other editorial information.
description: The Bovine Practitioner, Vol. 49, No. 2 (2015 Summer)
OXIDATIVE STRESS, SARCOPENIA, ANTIOXIDANT STRATEGIES AND EXERCISE: MOLECULAR ASPECTS
Creators: name: BRIOCHE, Thomas
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Sarcopenia could be currently defined as a geriatric syndrome initially characterized by a decrease in muscle mass that will get worse causing deterioration in strength and physical performance. A negative protein turnover, impaired mitochondrial dynamics and functions, a decreased muscle regeneration capacity, as well as an exacerbation of apoptosis are usually considered to be cellular mechanisms involved in muscle atrophy leading to sarcopenia. Here, we first present that muscle overproduction of reactive oxygen and nitrogen species (RONS) and oxidative stress observed during aging, are associated with sarcopenia, and then discuss how RONS are involved in redox-sensitive signaling pathways leading to sarcopenia. The identification of cost-effectiveness interventions to maintain muscle mass and physical functions in the elderly is one of the most important public health challenges.
Here, we also discuss about the efficiency of different kind of current antioxidant strategies against sarcopenia and future strategies. Since exercise is the best strategy to prevent and reverse sarcopenia, we also highlight that exercise acts as an antioxidant.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Supplementary document for A rapid theoretical method for inverse design on Tip-enhanced Raman spectroscopy (TERS) probe - 6356543.pdf
Creators: name: Yi, Jun
name: Meng, Zhao-Dong
name: Tian, Zhong-Qun
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental note
CUTANEOUS FREE RADICAL INDUCTION BY SUNLIGHT IN DIFFERENT SPECTRAL REGIONS AND COUNTERACTION BY SYSTEMICALLY OR TOPICAL APPLIED ANTIOXIDANTS
Creators: name: MEINKE, Martina
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: In order to assess the effect of the different spectral solar regions on the development of free radicals in skin, in vivo electron paramagnetic resonance investigations with human volunteers and ex vivo studies on excised human and porcine skin were carried out. For all skin probes, the ultraviolet spectral region stimulates the most intensive radical formation, followed by the visible and the near infrared regions. A comparison between the different skin models shows that for both regions, the fastest and highest production of free radicals could be detected in vivo, followed by excised porcine and human skin. Additional studies indicated that the intake of vegetable extract and the topical application of formulations rich in antioxidants could reduce the oxidative stress in the skin.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
B1MG D3.4 Phenotypic and clinical metadata framework — 1v0
Creators: name: Beliën, Jeroen
name: Gut, Ivo
name: Groot, Harmke
name: Ligtvoet, Maarten
name: Volkert, Pim
name: Gu, Wei
name: Korbel, Jan
name: Tebaldi, Michela
name: Urbini, Milena
name: Martinelli, Giovanni
name: Riba, Michela
name: Pinto, Catia
name: Soares, Flávio
name: Hermansson, Ulrika
name: Valencia, Alfonso
name: Ambrozaityte, Laima
name: Jarmalaite, Sonata
name: Aittomaki, Kristiina
name: Laivuori, Hannele
name: Lindström, Rutt
name: Hoen, Peter-Bram't
name: Becker, Regina
name: Serrano, Pablo
Publisher: name: Zenodo
Year: 2022
Subjects: B1MG
Beyond 1 Million Genomes
1+MG
1 Million Genomes Initiative
Phenotypic metadata
Clinical metadata
framework document
phenotypic and clinical metadata framework

description: The aim of the 1+MG member states initiative with coordination support of the Beyond 1 Million Genomes (B1MG) consortium is to develop a pan-European genome-based health data infrastructure to further develop and operationalise personalised medicine and to understand pharmacogenomics. In order to support the 1+MG member states initiative ambitions for sustainability policies regarding assets in the field of personalised medicine interoperability, a set of simple but well-aligned instruments needs to be prepared. One of the crucial instruments for 1+MG is a phenotypic and clinical metadata framework which describes, in a commonly understandable language, the principles, models and recommendations for sharing and linking of phenotypic and clinical metadata and genetic metadata between the member states. The current framework document proposes to adhere to standards for data capture and exchange. The main target is to provide guidance on which standards, terminologies and tools to use. Best practices, describing which ontologies are currently implemented in each member state, are described elsewhere (Deliverable 3.8: Documented best practices in sharing and linking phenotypic and genetic data - live working document1). This framework document will be part of the entire B1MG framework where other crucial instruments are taken care of by other work packages/working groups like Governance, ELSI and Technical Infrastructure. The B1MG framework document first of all aims at the 1+MG initiative while at the same time could be used as a base for the European Health Data Space2 (EHDS) and/or genomic data space.
title: Essays on Household Decision-Making and Mobile Access in Ethiopia
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 2021

description: In three essays, this dissertation analyzes how household behaviors affect the outcomes of anti-poverty programs and firm performances. Specifically, Essay I and II examine the impact of household decision-making mechanisms on household welfare in the presence of transfer and loan programs in Ethiopia. Essay III discusses the impact of mobile access by households on firm performance in Ethiopia. Using the household fixed effects model with instrumental variable regression method, Essay I analyzes the impact of aid transfers in Ethiopia via the channel of innate structure of bargaining dynamics. In examining general gender effects of bargaining power driven by loan programs, Essay II employs the propensity matching method and household-level fixed effect model. Finally, by utilizing an exogenous shock of transitioning from the 2G to 3G broadband network in 2008 in Ethiopia with the differences-in-differences and triple differences methods, Essay III investigates whether enhanced access to mobile communication increases competition as price information is more widely available to customers.
SKIN ANTI-AGEING AND SYSTEMIC REDOX EFFECTS OF SUPPLEMENTATION WITH MARINE COLLAGEN PEPTIDES AND PLANT-DERIVED ANTIOXIDANTS
Creators: name: KORKINA, Liudmila
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Recently, development and research of nutraceuticals based on marine collagen peptides (MCPs) have been growing due to their high homology with human collagens, safety, bioavailability through gut, and numerous bio- activities. The major concern regarding safety of MCPs intake relates to increased risk of oxidative stress connected with intense collagen synthesis, and to ROS production by MCPs-stimulated phagocytes. The case- controlled clinical-laboratory study was designed to evaluate skin anti-ageing and systemic redox effects of supplementation with the composition of marine collagen peptides and plant-derived skin-targeting antioxidants (coenzyme Q10+grape skin extract+luteolin+selenium).
The data obtained clearly show the improvement of skin properties (elasticity, sebum production, biological age, and dermal ultrasound markers) due to enhanced collagen synthesis without risk of oxidative stress that is usually connected with the synthesis. Metabolic data showed significant increase of plasma hydroxyproline and ATP storage in erythrocytes. Redox parameters, GSH/coenzyme Q10 content, and GPx/GST activities were unchanged, while NO and MDA were moderately increased within, however, normal range of values.
The hormesis-like action of the supplementation suggests this mechanism underlying its anti-ageing and energising effects.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
THE PATHENINE/VANINE PATHWAY CONTROLS ROS-INDUCED SKIN FIBROSIS
Creators: name: KAVIAN, Niloufar
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Our team works on systemic sclerosis (SSc), a disease that is characterized by vascular dysfunction, skin and visceral fibrosis, and dysimmunity. Oxidative stress in endothelial cells and fibroblasts is partly responsible for the activation of these cells and the consecutive oxidization of DNA-topoisomerase-1 that leads to the breach of immune tolerance and the production of autoantibodies in SSc patients. Our work regards the mechanisms of spreading and perpetuation of cellular activation and oxidative stress through various tissues and organs such as skin, lungs and kidneys.
We report that in vitro and in various relevant mouse models of SSc, pantethine exerts vasculoprotective and anti-fibrotic effects by protecting endothelial cells and fibroblasts from oxidative and nitrosative stresses. These beneficial effects are the consequences of the inhibition of endothelial microparticle shedding and of proper anti- oxidant properties. Pantethine is metabolized by pantetheinase/vanine-1 enzyme into pantothenic acid and cystamine. Therefore, the level of pantethine depends on the enzymatic activity of its metabolizing enzyme pantetheinase/vanin-1. The pantetheinase-vanin-1 activity is significantly increased in the skin and in the blood of mice and of patients with SSc compared to controls. This imbalance favours the conversion of the vasculoprotective pantethine into pantothenic acid and cysteamine that, in sharp contrast with pantethine, act as pro-fibrotic and pro-oxidative agents. Vanin-1-/- animals do not develop fibrosis, vascular dysfunction and autoimmunity when submitted to experimental SSc. Thus, the levels of pantetheinase/vanin-1 activity determine the severity of the disease and this data suggests that the restoration of pantethine levels could treat systemic sclerosis. Altogether, the imbalance in the pantethine/pantetheinase-vanin-1 pathway is a new argument for the role of ROS as a pivotal feature of the pathophysiology of SSc.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
title: Oxidized Extracellular DNA as a Stress Signal in Human Cells
Creators: name: Ermakov, Aleksei V.
name: Konkova, Marina S.
name: Kostyuk, Svetlana V.
name: Izevskaya, Vera L.
name: Baranova, Ancha
name: Veiko, Natalya N.
Publisher: name: Hindawi Publishing Corporation
Year: 2013
Subjects: subject: Adaptive responses
subject: Bystander effect
subject: DNA double-strand breaks
subject: Extracellular DNA
subject: Oxidative stress
subject: Reactive oxygen species
subject: Human umbilical vein endothelial cells
subject: Mesenchymal stem cells.

description: The term “cell-free DNA” (cfDNA) was recently coined for DNA fragments from plasma/serum, while DNA present in in vitro cell culture media is known as extracellular DNA (ecDNA). Under oxidative stress conditions, the levels of oxidative modification of cellular DNA and the rate of cell death increase. Dying cells release their damaged DNA, thus, contributing oxidized DNA fragments to the pool of cfDNA/ecDNA. Oxidized cell-free DNA could serve as a stress signal that promotes irradiation-induced bystander effect. Evidence points to TLR9 as a possible candidate for oxidized DNA sensor. An exposure to oxidized ecDNA stimulates a synthesis of reactive oxygen species (ROS) that evokes an adaptive response that includes transposition of the homologous loci within the nucleus, polymerization and the formation of the stress fibers of the actin, as well as activation of the ribosomal gene expression, and nuclear translocation of NF-E2 related factor-2 (NRF2) that, in turn, mediates induction of phase II detoxifying and antioxidant enzymes. In conclusion, the oxidized DNA is a stress signal released in response to oxidative stress in the cultured cells and, possibly, in the human body; in particular, it might contribute to systemic abscopal effects of localized irradiation treatments.
Modelling the decarbonization pathways of Rwanda's power system and ensuring energy security
Creators: name: Nizeyimana, Ernest
name: Ngangure, Diana
Publisher: name: Zenodo
Year: 2025

description: This presentation was presented during the Energy Modelling Platform for Africa 2025 in Addis Ababa, Ethiopia. The input data was received from different sources for the past 3 years (2021-2023). The data included primary sources of energy and its reserves, power installed capacity, generated electricity and demand.

Through the MUIO – Osemosys, three scenarios were studied and these were:

·       BAU – considering the committed plants and plans of the Rwanda;

·       Import reduction-reduction of power imports that affect the grid stability and

·       Renewable energy target- constraining the Renewable energy share at 70% from 2030- 2050 in line with the SDG and NDC targets.
ANALYSIS OF WILLIAM FAULKNER'S WORLD VIEW IN A ROSE FOR EMILY (STUDY OF LUCIEN GOLDMANN'S GENETIC STRUCTURALISM) by Kahar Dwi Prihantono
Creators: name: Young, Braydon
Publisher: name: Zenodo
Year: 2022
Subjects: genetic structuralism; A Rose for Emily; social structure; world view

description: This study aims to gain an understanding of William Faulkner 's world view in the short story “A Rose for Emily” ( ArfE ). This research uses a dialectical method with a genetic structuralism approach. The problems discussed include (1) the structure of the short story; (2) William Faulkner 's worldview ; (3) social structure, and social groups represented by the author. Research data in the form of sentences or paragraphs, dialogues, and monologues contained in the short story ArfE by William Faulkner . Based on the analysis of the structure of the short story, the writer finds the relation between cultural opposition, social opposition, natural opposition, and human opposition.
AABP Association and Conference News
Creators: name: American Association Of Bovine Practioners,
Publisher: name: The Bovine Practitioner
Year: 2014
Subjects: American Association of Bovine Practitioners
cattle
congresses

description: Description and highlights of the 47th Annual Convention American Association of Bovine Practitioners (2014) and information about officers, district news, events, awards, and other news.
description: The Bovine Practitioner, Vol. 49, No. 1 (2015 Spring)
SKIN REDOX BALANCE MAINTENANCE: THE NEED FOR AN NRF2- ACTIVATORS DELIVERY SYSTEM
Creators: name: BEN YEHUDA GREENWALD, Maya
name: BEN SASSON, Shmuel
name: BIANCO- PELED, Havazele
name: KOHEN, Ron
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The skin, functions as a barrier between our body and the environment. Therefore, skin is consistently exposed to physical damages (e.g. wounds, sunburns) and to various exogenous and endogenous sources producing reactive oxygen species (e.g. air pollutants, ionizing and non-ionizing irradiation, toxins, mitochondrial metabolism, enzymes activity, etc.). Although skin has developed an array of counteracting defense mechanisms, augmented or continued reactive oxygen species activity may result in oxidative stress leading to many skin disorder including inflammatory diseases, pigmenting disorders and some types of cutaneous malignancies. The nuclear factor erythroid 2–related factor 2 (Nrf2) is an emerging regulator of cellular resistance and of defensive phase II enzymes. Induction of the Keap1-Nrf2 pathway may have a beneficial effect in treatment of a large number of skin disorders, by stimulating the endogenous defense mechanism. However, sustained and enhanced activation of this pathway is detrimental and limits the therapeutic potential of Keap1-Nrf2 activators.
Here, we suggest a novel strategy for maintenance of skin redox homeostasis by modulating the Keap1-Nrf2 pathway using delivery systems.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Bovine Practitioner Vol. 49, No. 1 (2015 Spring). Front matter
Creators: name: American Association Of Bovine Practioners,
Publisher: name: The Bovine Practitioner
Year: 2014

description: Cover, masthead, table of contents, and other editorial information.
description: The Bovine Practitioner, Vol. 49, No. 1 (2015 Spring)
title: Microplastics in the Tidal Freshwater Potomac
Creators: name: Rhoades, Benjamin
name: Nguyen, Han
name: Wigode, Evan
name: Sklarew, Daniel M.
name: Foster, Gregory D.
Publisher: name: George Mason University
Year: 2019
Subjects: subject: Freshwater Ecology
subject: Microplastics

description: Microplastics (MPs) are pieces of plastic between 0.33mm and 5mm and represent a near ubiquitous type of pollution and have been found in almost all bodies of water sampled. MPs represent both an ecological and a public health threat, as vectors of toxic chemicals. Only one peer-reviewed paper quantifies the microplastics issue in the Chesapeake Bay region, with no published findings regarding microplastics in tidal freshwater Potomac River. Yonkos et al. (2015) considers population density of a watersheds in the Bay region as a factor influencing MP concentrations. This study investigates MPs in the Potomac River basin and the impact of land development on MP concentrations.
Bovine Practitioner Vol. 48, No. 2 (2014 Summer). Front matter
Creators: name: American Association Of Bovine Practioners,
Publisher: name: The Bovine Practitioner
Year: 2014

description: Cover, masthead, table of contents, and other editorial information.
description: The Bovine Practitioner, Vol. 48, No. 2 (2014 Summer)