cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
STUDIO DEL VELENO DEL PARASSITOIDE DI AFIDI APHIDIUS ERVI
Creators: name: Aden Abdi, Fatima
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2015

description: Aphidius ervi (Hymenoptera, Braconidae) is an endophagous parasitoid of the pea aphid Acyrthosiphon pisum (Homoptera, Aphididae) and of various cereal aphids.
Parasitized aphids show a notable inhibition of reproductive activity and metabolic alterations, which are nutritionally relevant for the developing wasp juveniles. Host regulation factors produced by A. ervi and responsible of these alterations are both of maternal origin, injected at the oviposition along with the egg, and of embryonic origin, in particular released by cells derived from the dissociation of the serosal membrane of the parasitoid embryo, denoted as teratocytes.
The venom, injected at the oviposition, is the major factor responsible for the castration of the hosts, which is caused by the induction of apoptosis in the germarial cells of the aphid ovarioles. This event is triggered by a γ-glutamyl transpeptidase (Ae-γ-GT), which may likely induce an oxidative stress in germarial cells.
Here this hypothesis was firstly tested, assessing if the exposure to Ae-γ-GT induce a change of glutathione (GSH) titer in the host tissues. GSH, measured by high performance liquid chromatography, was found to be significantly reduced in parasitized aphids and this difference was largely due to GSH decrease in the ovaries. Due to GSH role in the protection of oxidative stress, its decrease in parasitized aphids corroborates the experimental hypothesis.
Transcriptomic analysis of the venom gland by RNAseq Ae-γ-GT allowed the identification of two isoforms of Ae-γ-GT (Ae-γ-GT1 and Ae-γ-GT2), which showed 51% sequence identity. Quantitative studies of their expression profile in venom glands and in the rest of the body have been performed using quantitative Real Time PCR, assessing the changes of the transcription rates as affected by time and oviposition activity.
These two isoforms of Ae-γ-GT were produced in vitro in insect cells by recombinant baculovirus to carry out a more comprehensive molecular and functional characterization, aiming to shed light on their role in the host regulation process.
This objective was also tentatively pursued by developing a gene silencing approach by RNAi (RNA interference). Indeed, three administration methods for the delivery of dsRNA targeting the Ae-γ-GT1 have been designed and their efficiency comparatively assessed. The first experimental approach consisted of haemocoelic injections of dsRNA in A. ervi pupae, then the delivery through the host aphid was attempted, by injecting dsRNA in the haemocoel of parasitized host aphids, or by feeding these latter on a liquid diet containing the dsRNA. The obtained results did not allow to select any of the experimental approaches pursued, as the results were inconsistent and further research work is necessary to develop a reliable and effective protocol to silence Ae-γ-GT.
title: Experiences of Iranian women entrepreneurs in the ICT (information and communications technology) sector
Creators: name: Emadi, Nafiseh
Publisher: name: Memorial University of Newfoundland
publisherIdentifier: https://ror.org/04haebc03
publisherIdentifierScheme: ROR
Year: 2024

description: Despite the expansion of women’s entrepreneurship in Iran, women still face many challenges that make it difficult to start a business. Barriers such as limited funding, gender biases, limited government support, and family responsibilities have been in the way of women entrepreneurs for many years and women face more barriers than men (Shinnar, Giacomin, & Janssen, 2012). Still, information and communication technologies (ICTs) are appearing as increasingly valuable business tools for women entrepreneurs. That being the case, I investigated the barriers to Iranian women entrepreneurs in the ICT sector as well as their resilience to those barriers. To conduct my research, I collected already published interviews with 12 women entrepreneurs in the media, prepared a codebook, and analyzed them through feminist content analysis. I found that challenges to women’s entrepreneurship in Iran in the ICT sector include some obstacles. These obstacles contain those that are specific to Iran, such as the lack of foreign trade, economic instability, bribery, brain drain, sanctions, decrease in tourism, filtering, low internet speed, lack of cutting-edge technology, some Islamic laws practice in Iran. Obstacles also include the lack of trust in women for activities outside the home, gender role expectations (including family responsibilities and childcare), literacy and education, finance, a lack of professional human resources to be recruited for their companies, and time-consuming and inefficient bureaucracy. In terms of women entrepreneurs’ resilience, I found that women tried to navigate their challenges by working hard, having motivation, perseverance, and self-confidence, conducting time management and responsibility, and acquiring related skills and knowledge. Women had resilience while receiving support from family members, reducing household and childcare pressures, as well as developing cooperation and assistance from others and practicing teamwork. Through a better understanding of their challenges, the findings of my research would benefit Iranian women entrepreneurs, especially in the ICT sector.
title: Thirty-Third Annual Commencement of the State Teachers College
title: Annual Commencement
titleType: AlternativeTitle
Creators: name: State Teachers College
Publisher: name: Maryland Shared Open Access Repository
Year: 1936
Subjects: subject: State Teachers College
subject: Commencement ceremonies

description: Commencement program for June 8, 1936, which may include written corrections and annotations. While every effort is made to ensure accuracy in commencement programs, printing deadlines sometimes prevent inclusion of candidates' names or may result in the use of names of persons not completing graduation requirements.
Supplementary document for Demonstration of hierarchical arrangement of persistent luminescent microparticles in direct doping-prepared photonics glasses using second-harmonic generation microscopy - 5882453.pdf
Creators: name: Annurakshita, Shambhavee
name: Lahti, Vilma
name: Petit, Laeticia
name: Bautista, Godofredo
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Supplement 1
AI POWERED PLACEMENT PREPARATION PLATFORM
Creators: name: NILANI S
name: NIVETHA D
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Artificial Intelligence
subject: Artificial intelligence
subject: MERN STACK
subject: QUIZ
subject: Interdisciplinary Placement/methods
subject: Interdisciplinary Placement/trends
subject: Interdisciplinary Placement/history
subject: Interdisciplinary Placement/legislation & jurisprudence
subject: Interdisciplinary Placement/organization & administration

description: This project aims to develop an AI enhanced quiz platform tailored for placement interview preparation using the MERN stackThe platform integrates personalized quizzes, robust anti cheating measures, and real time feedback via an integrated chatbotBy leveraging innovative AI technologies, the platform enhances student engagement and readiness while ensuring a secure andeffective learning experience.
AI POWERED PLACEMENT PREPARATION PLATFORM
Creators: name: NILANI S
name: NIVETHA D
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Artificial Intelligence
subject: Artificial intelligence
subject: MERN STACK
subject: QUIZ
subject: Interdisciplinary Placement/methods
subject: Interdisciplinary Placement/trends
subject: Interdisciplinary Placement/history
subject: Interdisciplinary Placement/legislation & jurisprudence
subject: Interdisciplinary Placement/organization & administration

description: This project aims to develop an AI enhanced quiz platform tailoredfor placement interview preparation using the MERN stackThe platform integrates personalized quizzes, robust anti cheatingmeasures, and real time feedback via an integrated chatbotBy leveraging innovative AI technologies, the platform enhancesstudent engagement and readiness while ensuring a secure andeffective learning experience.
Where are all the babies? Does social/structural support moderate the relationship between career aspirations and childbearing intentions/timing for young women in the UK?
Creators: name: Leney, Melanie
Publisher: name: University of Tasmania
Year: 2024

description: Total fertility rates have been falling and are currently well below replacement level in the United Kingdom (UK). Below replacement fertility impacts the economy and has personal impacts on women who are not realising their childbearing wishes. This study investigated if social or structural support moderated the hypothesised negative relationship between career aspirations and childbearing intentions. We recruited 300 female participants between 18 and 28 years from the UK via Prolific (2014). The participants completed a survey with questions regarding childbearing intentions, desired age at first birth, ideal number of children, career aspirations, and expected levels of social and structural support. A moderation analysis was conducted excluding LGBTQIA+ participants as their inclusion was found to have a significant impact on the model. No interactions were significant; however, career aspirations and structural support were positively associated with childbearing intentions. Structural support was positively associated with number of children desired. Social support was negatively associated with ideal age at first birth. Structural support is important for childbearing intentions and social support is important for having children sooner. Further research should clarify what structural support facets will enable people to realise their childbearing intentions.
ИШЕМИК ИНСУЛЬТНИНГ ТИКЛАШ ДАВРИДА КОМПЛЕКС РЕАБИЛИТАЦИЯНИНГ ХУСУСИЯТЛАРИ
Creators: name: Саломова, Нилуфар
name: Жамолов, Шариф
Publisher: name: Zenodo
Year: 2024

description: Ҳозирги вақтда бош мия инсульти аҳоли ногиронлигининг етакчи сабабларидан бири бўлиб қолмоқда (Иванова Г. E. ва бошқ. 2022; Помников В. G. ва бошқ., 2023). Беморларнинг ушбу гуруҳини реабилитация қилиш инсульт натижасида келиб чиқадиган касалликларни тузатишда муҳим аҳамиятга эга (Хасанова Д. R. ва бошқ., 2016; Levin О. S., Боголепова А. N., 2016). Инсульт билан оғриган беморларни реабилитация қилишнинг замонавий кўриниши реабилитация тадбирларининг эрта бошланишини, бемор ва унинг қариндошларини фаол жалб қилган ҳолда изчил ва узлуксиз реабилитация жараёнини таклиф қилади (Фахретдинов В. V. ва бошқ., 2019; Барулин А. E. ва бошқ., 2021).
Use of Keyline for planting cork oaks and holm oaks in agro-forestry systems
Creators: name: Pacheco Marques, Pedro
Publisher: name: Zenodo
Year: 2025
Subjects: landscape
land management
Agroforestry
new planting system
Farming equipment
machinery

description: The Keyline system improves water distribution in landscapes by creating gently sloped curves that redirect water from valleys to drier areas. Utilizing minimal disturbance techniques; it enhances soil health and vegetation growth; achieving an 80% survival rate for planted species.
TALABALARDA PERFEKSIONIZMNING PSIXOLOGIK OMILLARI
Creators: name: Kurbanova, Muxlisa
Publisher: name: Zenodo
Year: 2025

description: Ushbu maqola talabalarda perfektsionizmning shakllanishiga ta'sir etuvchi asosiy psixologik omillarni o'rganadi. Maqolada talabalarning shaxsiy xususiyatlari (o'ziga yuqori talab qo'yish, tanqidga sezuvchanlik, muvaffaqiyatsizlikdan qo'rqish), kognitiv jarayonlari (mukammallikka intilish, qora va oq fikrlash, haddan tashqari umumlashtirish), hissiy holatlari (xavotirlik, stress, aybdorlik hissi) va ijtimoiy omillar (ota-onalarning talablari, o'qituvchilarning baholashi, tengdoshlarning ta'siri) tahlil qilinadi. Shuningdek, perfektsionizmning talabalarning psixologik farovonligi va o'quv faoliyatiga ta'siri ko'rib chiqiladi.
title: Deterioro cognitivo postoperatorio en pacientes adultos post cirugía abdominal bajo anestesia general
Creators: name: Cervantes Castillo, Yesenia Esmeralda
Publisher: name: Tecnológico de Monterrey
publisherIdentifier: https://ror.org/03ayjn504
publisherIdentifierScheme: ROR
Year: 2023
Subjects: classificationCode: 3.2
subject: FOS: Clinical medicine

description: Es bien conocido que los procesos neuronales son transgredidos por la anestesia general, lo que podría influir en los estados cognitivos y conductuales. Hasta ahora, los estudios clínicos realizados en pacientes en ambos extremos de la vida son, en gran medida, retrospectivos y desconcertantes, pero sugieren una asociación entre la anestesia y la evolución cognitiva a largo plazo. Se realizó un estudio observacional prospectivo aplicando las escalas SCIP-S y Test de matrices progresivas de Raven, antes y 24 horas después de la cirugía en pacientes adultos postoperados de cirugía abdominal bajo anestesia general en el Hospital metropolitano “Dr. Bernardo Sepúlveda”, con la finalidad de identificar el grado el grado de modificación en funciones cognitivas especiales (Aprendizaje verbal inmediata, Memoria de trabajo, Fluidez verbal, Aprendizaje verbal diferido Orientación visoespacial); como objetivos secundarios se incluyeron: estimar la incidencia de cambios cognitivos en el postoperatorio inmediato, determinar la existencia de diferencias estadísticamente significativas en la prevalencia de trastornos neurocognitivos en el postoperatorio e identificar los factores contribuyentes para la presentación de trastornos neurocognitivos en el postoperatorio inmediato. En este estudio, no encontramos diferencia significativa en la función cognitiva global del preoperatorio versus el postoperatorio en pacientes operados de cirugía abdominal. Se encontró diferencia significativa únicamente en la función de Fluidez verbal, con una mejor puntuación en el postoperatorio. Solo dos pacientes del estudio (5.41%) presentaron un cuadro de delirium postoperatorio (DPO) en las primeras 24 horas, dichos pacientes tenían una edad igual o mayor de 65 años.
Table S1: Number of Subjects with Less Than Three Image Slices Selected
Creators: name: Nandy, Debmalya
Publisher: name: figshare
Year: 2022
Subjects: subject: 70703 Veterinary Diagnosis and Diagnostics
subject: FOS: Veterinary sciences

description: Table S1. Number of subjects for whom less than three slices are selected from their respective DICOM files for data generation.
ResearchBox 572, 'Greed: What is it Good for? ', https://researchbox.org/572
Creators: name: Karlijn Hoyer
name: marcel Zeelenberg
name: Seger Breugelmans
Publisher: name: Zenodo
Year: 2022

description: Box title: 'Greed: What is it Good for? '   Reference: Hoyer K, Zeelenberg M, Breugelmans SM. (2022) 'Greed: What Is It Good for?'. Personality and Social Psychology Bulletin. :014616722211403. doi: 10.1177/01461672221140355Note: this backup was created automatically by a ResearchBox bot
Table S2: Number of Subjects with Less Than Three Image Slices Selected
Creators: name: Nandy, Debmalya
Publisher: name: figshare
Year: 2022
Subjects: subject: 70703 Veterinary Diagnosis and Diagnostics
subject: FOS: Veterinary sciences

description: Table S2. Number of subjects for whom less than three slices are selected from their respective DICOM files for data generation.
Neocortical_development_in_organotypic_mouse_brain_cultures_supplement
Creators: name: Bak, Aniella
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 320999
subject: Neurosciences not elsewhere classified

description: Supplemental material for the paper entitled "Temporal Dynamics of Neocortical Development in Organotypic Mouse Brain Cultures: A Comprehensive Analysis"
Table S2: Number of Subjects for Whom Facial Muscle is Used as Normal Tissue
Creators: name: Nandy, Debmalya
Publisher: name: figshare
Year: 2022
Subjects: subject: 70703 Veterinary Diagnosis and Diagnostics
subject: FOS: Veterinary sciences

description: Table S2: Number of subjects for whom facial muscle is used as the “normal” tissue for data generation
title: Thirty-Fifth Annual Commencement of the State Teachers College
title: Annual Commencement
titleType: AlternativeTitle
Creators: name: State Teachers College
Publisher: name: Maryland Shared Open Access Repository
Year: 1938
Subjects: subject: State Teachers College
subject: Commencement ceremonies

description: Commencement program for June 13, 1938, which may include written corrections and annotations. While every effort is made to ensure accuracy in commencement programs, printing deadlines sometimes prevent inclusion of candidates' names or may result in the use of names of persons not completing graduation requirements.
title: Thirty-Fourth Annual Commencement of the State Teachers College
title: Annual Commencement
titleType: AlternativeTitle
Creators: name: State Teachers College
Publisher: name: Maryland Shared Open Access Repository
Year: 1937
Subjects: subject: State Teachers College
subject: Commencement ceremonies

description: Commencement program for June 8, 1937, which may include written corrections and annotations. While every effort is made to ensure accuracy in commencement programs, printing deadlines sometimes prevent inclusion of candidates' names or may result in the use of names of persons not completing graduation requirements.
A Systematic Review of Emerging Trends in Student-Led Research: An Inventory of Published Papers for the First Trimester of 2025
Creators: name: Sumayang, Joann
name: Secretaria, Kenneth
name: Ole, Carmelyn
name: Tadlas, Melodia
Publisher: name: San Isidro College
Year: 2025
Subjects: Bibliometric Analysis
Higher Education Research
Published Research
Student-Led Research
Systematic Review
Undergraduate Research

description: Student-led research is gaining momentum as a meaningful contributor to academic growth and innovation in education. These publications provide a unique lens into current academic issues as explored by student researchers, offering insights often grounded in new, real-world perspectives. Tracking and analyzing these works help institutions recognize valuable patterns, themes, and practical contributions that enrich educational practice and support a culture of scholarly engagement. A careful review of selected student-authored papers was conducted using a structured screening and analysis approach. The findings were organized and interpreted by applying thematic and comparative methods to highlight emerging insights from student research contributions. The study revealed that student-led research is increasingly rooted in themes of personal relevance, community engagement, and social well-being. Across various topics, students showed a strong ability to explore real-life concerns using appropriate and meaningful research methods. These studies highlight a shift in research culture where students act as learners and changemakers. The findings underscore the importance of supporting student inquiry through structured guidance, institutional resources, and inclusive academic spaces. The study confirms the value of reflective, experience-based research in fostering holistic learning and social awareness.
Supplementary document for Perovskite solar cells integrated with blue cut-off filters for mitigating light-induced degradation - 5882738.pdf
Creators: name: Yoon, Beomhee
name: Park, Chul-Soon
name: Song, Hyung-Jun
name: Kwak, Jeonghun
name: Lee, Sang-Shin
name: Lee, Hyunho
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental document
Sukuk : Structures, Conformité Shariah et Controverses
Creators: name: HOUAM, Raja
name: HOUAM, Rida
name: MAIMOUN, Ahmed
Publisher: name: Zenodo
Year: 2024
Subjects: Sukuk; Finance Islamique; Shariah; Obligations; Structures de Sukuk

description: Le terme "sukuk", souvent désigné comme "obligations islamiques" ou "obligations conformes à la Shariah", représente une forme approuvée de dette selon la loi islamique. Contrairement aux obligations conventionnelles, les sukuk impliquent la propriété d'actifs sous-jacents plutôt que des obligations de dette pure. Cette approche permet aux investisseurs de participer directement aux actifs économiques tout en respectant les principes de partage des risques et des récompenses de la Shariah. Cette distinction est cruciale car elle reflète les valeurs fondamentales de l'équité et de la responsabilité sociale dans la finance islamique. Cet article théorique explore en profondeur les caractéristiques et les types variés des sukuk, ainsi que les défis et les controverses qui les entourent dans le contexte financier islamique moderne.
title: Thirty-Sixth Annual Commencement of the State Teachers College
title: Annual Commencement
titleType: AlternativeTitle
Creators: name: State Teachers College
Publisher: name: Maryland Shared Open Access Repository
Year: 1939
Subjects: subject: State Teachers College
subject: Commencement ceremonies

description: Commencement program for June 12, 1939, which may include written corrections and annotations. While every effort is made to ensure accuracy in commencement programs, printing deadlines sometimes prevent inclusion of candidates' names or may result in the use of names of persons not completing graduation requirements.
Mobile Clinics Intervention Program (MCIP) for Oral Cholera Vaccine (OCV) among Internally Displaced Persons (IDPs) in Mogadishu, Somalia
Creators: name: Uwase, Andromede
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Ongoing conflicts and climate change impacts in Somalia have led to high displacement of people and severe cholera burden due to limited access to clean water, safe sanitation facilities, hygiene resources, healthcare infrastructure, and oral cholera vaccines (OCV). Low OCV coverage persists in internally displaced persons (IDP) camps because of accessibility barriers such as lack of transportation to healthcare facilities, security issues, and financial constraints. Additionally, vaccine hesitancy due to cultural beliefs, misconceptions, mistrust of healthcare workers and the government, and language barriers contribute to the low OCV coverage among IDPs. To improve OCV uptake among IDPs in Mogadishu, Somalia, Mobile Clinic Intervention Program (MCIP) implementation is proposed. MCIP has two major components: 1) Social mobilization campaigns tailored to the socio-cultural context to raise awareness about cholera prevention and address vaccine hesitancy and 2) Vaccine delivery directly to IDP camps in northern Mogadishu. Upon completion, MCIP's expected outcomes include 1) Increasing vaccine coverage by 60%, 2) Improving knowledge and acceptability of OCV by 50% through educational campaigns and 3) Increasing cholera prevention and control measures by 70%. Increasing OCV accessibility and acceptability through MCIP is therefore subjected to reducing cholera morbidity and mortality rates among IDPs in Mogadishu, Somalia.
title: Applying Social Community Identity and Spatial Theory to Extend Our Understanding of Ala al-Din Khammas: The Warrior-Scholar Who Trained Saddam Hussein’s Military Leaders
Creators: name: Aboul-Enein, Youssef
Publisher: name: Maryland Shared Open Access Repository
Year: 2025
Subjects: subject: Military Studies
subject: Military History
subject: Islamic studies
subject: Middle Eastern history
subject: Iraqi History
subject: Iraqi Military
subject: Early Caliphate
subject: Ala al-Din Khammas (General)

description: Ala’ al-Din Khammas is unique among Saddam Hussein’s generals interviewed in 2009 by U.S. military officials for his prolific publications produced while in Iraq’s military and after his retirement. His military manuals developed during the Iran-Iraq War (1980-1988) and distributed to Iraq’s field commanders, would be instrumental in stabilizing the southern Basra front. Khammas’ is also rare among Saddam’s officers for his effort to introduce American military works to Iraqi military officers. This study investigates Khammas’ intellectual imprint on Iraqi officers that would later confront American forces in Operations Desert Storm and Iraqi Freedom. This qualitative interpretive study critically examines Khammas’ magnum opus, The Arab Art of War (1999) which argues that Arabs have their own distinct art of war worthy of careful study developed in the 7th century. It experiments with identity and spatial relationship theories of Anderson (2016), and Tuan (1990) as frameworks in a novel approach to military analysis and expands our understanding of Khammas himself and his argument of a distinct Arab art of war. Applying these theoretical frameworks make up for Khammas intense focus on battlefield tactics and identifies two overarching principles embedded throughout his work, the use of extreme contrasts in terrain and how a changing Arab identity enabled a 7th century hybrid combination of tribal and conventional war that can be called a distinct all-encompassing Arab art of war.
Impact of e-cigarette health warnings on motivation to vape and smoke
Creators: name: Baig S.A
name: Kameny M.R
name: Brewer N.T
name: Mendel J.R
name: Ribisl K.M
name: Jeong M
name: Hall M.G
name: Lazard A.J
name: Noar S.M
Publisher: name: BMJ Publishing Group
Year: 2019

description: Background A prevailing hypothesis is that health warnings for electronic cigarettes (e-cigarettes) could drive people away from vaping and towards smoking cigarettes. We consider an alternative hypothesis that e-cigarette warnings discourage both vaping and smoking. Methods Participants were a national convenience sample of 2218 US adults who used e-cigarettes, cigarettes or both. In August 2018, we randomised participants to one of three warning types (control text about littering, text-only e-cigarette warning or pictorial e-cigarette warning). We further randomised participants viewing e-cigarette warnings to one of three topics (nicotine addiction, health hazards of use, or both health hazards and harms of use). The preregistered primary outcome was intentions to quit vaping among e-cigarette users. Secondary outcomes included interest in smoking and Tobacco Warnings Model constructs: attention, negative affect, anticipated social interactions and cognitive elaboration. Results Text warnings elicited higher intentions to quit vaping than control among e-cigarette users (d=0.44, p<0.001), and pictorial warnings elicited still higher intentions to quit vaping than text (d=0.12, p<0.05). Text warnings elicited lower interest in smoking compared with control among smokers (p<0.05); warnings had no other effects on interest in smoking among smokers or non-smokers. Text warnings about health hazards elicited higher intentions to quit vaping than nicotine addiction warnings. E-cigarette warnings also increased Tobacco Warnings Model constructs. Discussion E-cigarette health warnings may motivate users to quit vaping and discourage smoking. The most promising warnings include health hazards (other than nicotine addiction) and imagery. We found no support for the hypothesis that e-cigarette warnings could encourage smoking cigarettes.
Impact of Expanding Access to Continuous Glucose Monitoring Systems among Insulin Users with Type 1 or Type 2 Diabetes
Creators: name: Staats B
name: Pathak S
name: Kearin K
name: Albright J
name: Fuller K.A
name: Urick B.Y
name: Buse J.B
name: Sturmer T
name: Kahkoska A.R
Publisher: name: Mary Ann Liebert Inc.
Year: 2023

description: Background: Despite increased use of continuous glucose monitoring (CGM) systems, studies to quantify patterns of CGM use are limited. In December 2018, a policy change by a commercial insurer expanded coverage of CGM through the pharmacy benefit, creating an opportunity to evaluate the impact of this change on CGM utilization. Research Design and Methods: Pharmacy and medical claims from 2016 to 2020 were used to estimate the prevalence of CGM use among insulin users with type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) before and after the policy change. Change in CGM use was assessed using an interrupted time series design. Results: At the beginning of the study period, 18.8% of T1DM patients and 1.2% of T2DM patients used CGM. Use rose to 30.5% and 6.6% in the quarter before the policy change. The policy resulted in an immediate 9.5% (P < 0.0001) and 2.8% (P < 0.0001) change in use and increased the rate of quarterly change by 0.5% (P = 0.002) and 0.8% (P < 0.0001). At the end of the study period, 58.2% and 14.9% of T1DM and T2DM patients used CGM. Conclusion: CGM use significantly increased after addition to the pharmacy benefit. Rate of change in CGM use was lower in T1DM compared to the T2DM population, but overall use remained higher among patients with T1DM. Increased CGM use in the population studied aligns with those whose clinical guidelines suggest would most likely benefit. Additional work is needed to evaluate the impact of this benefit change on health care spending and outcomes.
Elucidating the Mechanisms Governing the Formation and Fe-based Catalytic Upgrading of Lignocellulosic Bio-oil from Flash Pyrolysis
Creators: name: Yang, sasha
Publisher: name: Monash University
Year: 2022
Subjects: subject: 30601 Catalysis and Mechanisms of Reactions
subject: FOS: Chemical sciences
subject: 90402 Catalytic Process Engineering
subject: FOS: Chemical engineering
subject: 90499 Chemical Engineering not elsewhere classified

description: This PhD study investigated the mechanism for the formation of bio-fuels during flash pyrolysis with the transformation of oxygen by biomass components. Core-shell, oxygen vacancy-rich magnetite nanocatalysts were further synthesized from coal fly ash for the ketonisation of acetic acid. The effect of impurity elements on catalyst properties, activity and reaction mechanism were also investigated. The results achieved are expected to inspire the optimization of the biomass flash pyrolysis process, leading to a remarkable improvement in yield and/or quality of initial products, and shed new insights on both value-added utilization of fly ash as well as upgrading of bio-oil.
Impact of intracellular innate immune receptors on immunometabolism
Creators: name: Rampanelli E
name: Li X
name: Chou W.-C
name: Ting J.P.-Y
Publisher: name: Springer Nature
Year: 2022

description: Immunometabolism, which is the metabolic reprogramming of anaerobic glycolysis, oxidative phosphorylation, and metabolite synthesis upon immune cell activation, has gained importance as a regulator of the homeostasis, activation, proliferation, and differentiation of innate and adaptive immune cell subsets that function as key factors in immunity. Metabolic changes in epithelial and other stromal cells in response to different stimulatory signals are also crucial in infection, inflammation, cancer, autoimmune diseases, and metabolic disorders. The crosstalk between the PI3K–AKT–mTOR and LKB1–AMPK signaling pathways is critical for modulating both immune and nonimmune cell metabolism. The bidirectional interaction between immune cells and metabolism is a topic of intense study. Toll-like receptors (TLRs), cytokine receptors, and T and B cell receptors have been shown to activate multiple downstream metabolic pathways. However, how intracellular innate immune sensors/receptors intersect with metabolic pathways is less well understood. The goal of this review is to examine the link between immunometabolism and the functions of several intracellular innate immune sensors or receptors, such as nucleotide-binding and leucine-rich repeat-containing receptors (NLRs, or NOD-like receptors), absent in melanoma 2 (AIM2)-like receptors (ALRs), and the cyclic dinucleotide receptor stimulator of interferon genes (STING). We will focus on recent advances and describe the impact of these intracellular innate immune receptors on multiple metabolic pathways. Whenever appropriate, this review will provide a brief contextual connection to pathogenic infections, autoimmune diseases, cancers, metabolic disorders, and/or inflammatory bowel diseases.
Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccination and Booster on Coronavirus Disease 2019 (COVID-19) Symptom Severity over Time in the COVID-OUT Trial
Creators: name: Nicklas J.M
name: Klatt N.R
name: Rao V
name: Siegel L.K
name: Saveraid H.G
name: Liebovitz D.M
name: Buse J.B
name: Hartman K.M
name: Belani H.K
name: Tignanelli C.J
name: Sherwood N.E
name: Bramante C.T.
name: Karger A.B
name: Pullen M.F
name: Proper J.L
name: Zaman A
name: Lindberg S
name: Tordsen W.J
name: Avula N
name: Cohen K
name: Lee S
name: Erickson S.M.
name: Patel B
name: Huling J.D
name: Ingraham N.E
name: Puskarich M.A
name: Hagen A.A
name: Murray T.A
name: Fricton R
name: Reddy N.V
name: Boulware D.R
name: Odde D.J
name: Fenno S.L
Publisher: name: Oxford University Press
Year: 2023

description: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination has decreasing protection from acquiring any infection with emergence of new variants; however, vaccination continues to protect against progression to severe coronavirus disease 2019 (COVID-19). The impact of vaccination status on symptoms over time is less clear. Methods: Within a randomized trial on early outpatient COVID-19 therapy testing metformin, ivermectin, and/or fluvoxamine, participants recorded symptoms daily for 14 days. Participants were given a paper symptom diary allowing them to circle the severity of 14 symptoms as none (0), mild (1), moderate (2), or severe (3). This is a secondary analysis of clinical trial data on symptom severity over time using generalized estimating equations comparing those unvaccinated, SARS-CoV-2 vaccinated with primary vaccine series only, or vaccine-boosted. Results: The parent clinical trial prospectively enrolled 1323 participants, of whom 1062 (80%) prospectively recorded some daily symptom data. Of these, 480 (45%) were unvaccinated, 530 (50%) were vaccinated with primary series only, and 52 (5%) vaccine-boosted. Overall symptom severity was least for the vaccine-boosted group and most severe for unvaccinated at baseline and over the 14 days (P <. 001). Individual symptoms were least severe in the vaccine-boosted group including cough, chills, fever, nausea, fatigue, myalgia, headache, and diarrhea, as well as smell and taste abnormalities. Results were consistent over Delta and Omicron variant time periods. Conclusions: SARS-CoV-2 vaccine-boosted participants had the least severe symptoms during COVID-19, which abated the quickest over time. Clinical Trial Registration. NCT04510194.
Impact of Vaping Prevention Advertisements on US Adolescents: A Randomized Clinical Trial
Creators: name: Noar S.M
name: Rohde J.A
name: Fendinger N.J
name: Hall M.G
name: Ma H
name: Brewer N.T
name: Gottfredson N.C
name: Kieu T
Publisher: name: American Medical Association
Year: 2022

description: Importance: Understanding whether prevention advertisements reduce susceptibility to vaping is important owing to concerning levels of adolescent vaping. Objective: To examine whether vaping prevention advertisements from the US Food and Drug Administration (FDA) national Real Cost campaign lead to lower susceptibility to vaping among adolescents. Design, Setting, and Participants: For this 3-group randomized clinical trial with parallel assignment, participants were US adolescents aged 13 to 17 years who were susceptible to vaping or current e-cigarette users, recruited from online panels. Adolescents were randomized to 1 of 2 Real Cost vaping prevention trial groups (health harms- or addiction-themed advertisements) or to a control group (investigator-created neutral videos about vaping). Adolescents completed 4 weekly online surveys at visits 1 to 4 over a 3-week period. Data were analyzed from December 1, 2021, to August 25, 2022. Interventions: Adolescents saw 3 randomly ordered 30-second video advertisements online at each of 3 weekly study visits (visits 1, 2, and 3). Main Outcomes and Measures: The primary trial outcome was susceptibility to vaping. Surveys also assessed susceptibility to smoking cigarettes to examine any spillover effects of vaping prevention advertisements on smoking outcomes. Both susceptibility measures had 3 items and ranged from 1 (indicating not susceptible) to 4 (indicating highly susceptible). The primary analyses compared Real Cost groups (combined) with the control group, while exploratory analyses compared the Real Cost groups with each other. Results: Participants were 1514 adolescents (1140 [75.3%] boys; mean [SD] age, 15.22 [1.18] years), including 504 randomized to the Real Cost health harms group, 506 randomized to the Real Cost addiction group, and 504 randomized to the control group. Adolescents in the Real Cost groups (combined) had lower susceptibility to vaping at visit 4 than those in the control group (b = -0.21; 95% CI, -0.32 to -0.10). The Real Cost groups did not differ from one another on susceptibility to vaping (visit 4: b = -0.05; 95% CI, -0.17 to 0.07). Adolescents in the Real Cost groups (combined) also had lower susceptibility to smoking cigarettes than those in the control group (b = -0.21; 95% CI, -0.32 to -0.10). For both vaping and smoking, Real Cost groups had less positive attitudes (vaping: b = -0.27; 95% CI, -0.40 to -0.14; smoking: b = -0.23; 95% CI, -0.39 to -0.08) compared with the control group. Conclusions and Relevance: These findings suggest that vaping prevention advertisements from the FDA Real Cost campaign led to lower adolescent susceptibility to vaping and had beneficial spillover effects on cigarette smoking outcomes. Tobacco prevention campaigns can help reduce youth tobacco use. Trial Registration: ClinicalTrials.gov Identifier: NCT04836455.
Supplementary document for Three-dimensional structure determination of gold nanotriangles in solution using X-ray free-electron laser single-particle analysis - 5882987.pdf
Creators: name: Nakano, Miki
name: Miyashita, Osamu
name: Joti, Yasumasa
name: Suzuki, Akihiro
name: Mitomo, Hideyuki
name: Niida, Yoshiya
name: Yang, Ying
name: Yumoto, Hirokatsu
name: Koyama, Takahisa
name: Tono, Kensuke
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Impact of the hepatoselective glucokinase activator TTP399 on ketoacidosis during insulin withdrawal in people with type 1 diabetes
Creators: name: Pettus J.H
name: Valcarce C
name: Giovannetti E.R
name: Freeman J.L.R
name: Buse J.B
name: Madduri S
name: Dvergsten C
name: Boeder S.C
name: Dunn I
name: Klein K.R
Publisher: name: John Wiley and Sons Inc
Year: 2022

description: Aims: To determine the effect of TTP399, a hepatoselective glucokinase activator, on the risk of ketoacidosis during insulin withdrawal in individuals with type 1 diabetes (T1D). Materials and methods: Twenty-three participants with T1D using insulin pump therapy were randomized to 800 mg TTP399 (n = 12) or placebo (n = 11) for 7 to 10 days. After the treatment period, an insulin withdrawal test (IWT) was performed, during which insulin pumps were removed to induce ketogenesis. The IWT was stopped after 10 hours or if blood glucose reached >399 mg/dL [22.1 mmol/L], if beta-hydroxybutyrate (BHB) was >3.0 mmol/L, or for patient discomfort. The primary endpoint was the proportion of participants who reached BHB concentrations of 1 mmol/L or greater. Results: During the 7- to 10-day treatment period, mean fasting plasma glucose was significantly reduced (−27.6 vs. −4.4 mg/dL [−1.5 vs. −0.2 mmol/L]; P = 0.03) and there were fewer adverse events, including hypoglycaemia, in the TTP399-treated arm. During the IWT, no differences were observed between TTP399 and placebo in mean serum BHB concentration, mean duration of IWT, or BHB at termination of IWT. However, serum bicarbonate was numerically higher and urine acetoacetate was quantitatively lower in the TTP399-treated participants. As a result of higher bicarbonate values, none of the TTP399-treated participants met the prespecified criteria for diabetic ketoacidosis (DKA), defined as BHB >3 mmol/L and serum bicarbonate <18 mEq/L, compared to 42% of placebo-treated participants. Conclusions: When used as an adjunctive therapy to insulin, TTP399 improves glycaemia without increasing hypoglycaemia in individuals with T1D. During acute insulin withdrawal, TTP399 did not increase BHB concentrations and decreased the incidence of DKA.
title: Thirty-Ninth Annual Commencement of the State Teachers College
title: Annual Commencement
titleType: AlternativeTitle
Creators: name: State Teachers College
Publisher: name: Maryland Shared Open Access Repository
Year: 1942
Subjects: subject: State Teachers College
subject: Commencement ceremonies

description: Commencement program for May 27, 1942, which may include written corrections and annotations. While every effort is made to ensure accuracy in commencement programs, printing deadlines sometimes prevent inclusion of candidates' names or may result in the use of names of persons not completing graduation requirements.
title: Thirty-Eighth Annual Commencement of the State Teachers College
title: Annual Commencement
titleType: AlternativeTitle
Creators: name: State Teachers College
Publisher: name: Maryland Shared Open Access Repository
Year: 1941
Subjects: subject: State Teachers College
subject: Commencement ceremonies

description: Commencement program for June 9, 1941, which may include written corrections and annotations. While every effort is made to ensure accuracy in commencement programs, printing deadlines sometimes prevent inclusion of candidates' names or may result in the use of names of persons not completing graduation requirements.
title: Thirty-Seventh Annual Commencement of the State Teachers College
title: Annual Commencement
titleType: AlternativeTitle
Creators: name: State Teachers College
Publisher: name: Maryland Shared Open Access Repository
Year: 1940
Subjects: subject: State Teachers College
subject: Commencement ceremonies

description: Commencement program for June 10, 1940, which may include written corrections and annotations. While every effort is made to ensure accuracy in commencement programs, printing deadlines sometimes prevent inclusion of candidates' names or may result in the use of names of persons not completing graduation requirements.
Implementation of a best practice in cardiology (Bpc) program adapted from get with the guidelines® in brazilian public hospitals: Study design and rationale
Creators: name: de Paola, A.A.V
name: de Albuquerque, D.C
name: Curtis, A.B
name: Chrispim, P.P.M
name: Morosov, E.D.M
name: Silva, S.A
name: Taniguchi, F.P
name: Smith, Jr., S.C
name: Taubert, K
name: Morgan, L
name: Weber, B
name: Fonarow, G.C
name: Toth, C.P.P
name: Ribeiro, A.L.P
name: Bernardez-Pereira, S
Publisher: name: Arquivos Brasileiros de Cardiologia
Year: 2020

description: Background: There are substantial opportunities to improve the quality of cardiovascular care in developing countries through the implementation of a quality program. Objective: To evaluate the effect of a Best Practice in Cardiology (BPC) program on performance measures and patient outcomes related to heart failure, atrial fibrillation and acute coronary syndromes in a subset of Brazilian public hospitals. Methods: The Boas Práticas em Cardiologia (BPC) program was adapted from the American Heart Association’s (AHA) Get With The Guidelines (GWTG) Program for use in Brazil. The program is being started simultaneously in three care domains (acute coronary syndrome, atrial fibrillation and heart failure), which is an approach that has never been tested within the GWTG. There are six axes of interventions borrowed from knowledge translation literature that will address local barriers identified through structured interviews and regular audit and feedback meetings. The intervention is planned to include at least 10 hospitals and 1,500 patients per heart condition. The primary endpoint includes the rates of overall adherence to care measures recommended by the guidelines. Secondary endpoints include the effect of the program on length of stay, overall and specific mortality, readmission rates, quality of life, patients’ health perception and patients’ adherence to prescribed interventions. Results: It is expected that participating hospitals will improve and sustain their overall adherence rates to evidence-based recommendations and patient outcomes. This is the first such cardiovascular quality improvement (QI) program in South America and will provide important information on how successful programs from developed countries like the United States can be adapted to meet the needs of countries with developing economies like Brazil. Also, a successful program will give valuable information for the development of QI programs in other developing countries. Conclusions: This real-world study provides information for assessing and increasing adherence to cardiology guidelines in Brazil, as well as improvements in care processes.
Test and develop a method for the implementation of silvopastoral mosaics; using remote sensing approaches; that supports agricultural and forestry activity in areas of Pyrenean oak; which typically have low agricultural value
Creators: name: Pacheco Marques, Pedro
Publisher: name: Zenodo
Year: 2025
Subjects: Agroforestry
forest restoration
Multifunctional forest management
remote sensing data

description: Developing Silvopastoral Mosaics: Remote Sensing in Pyrenean Oak Areas.
title: Forty-First Annual Commencement of the State Teachers College
title: Annual Commencement
titleType: AlternativeTitle
Creators: name: State Teachers College
Publisher: name: Maryland Shared Open Access Repository
Year: 1944
Subjects: subject: State Teachers College
subject: Commencement ceremonies

description: Commencement program for August 25, 1944, which may include written corrections and annotations. While every effort is made to ensure accuracy in commencement programs, printing deadlines sometimes prevent inclusion of candidates' names or may result in the use of names of persons not completing graduation requirements.
title: Fortieth Annual Commencement of the State Teachers College
title: Annual Commencement
titleType: AlternativeTitle
Creators: name: State Teachers College
Publisher: name: Maryland Shared Open Access Repository
Year: 1943
Subjects: subject: State Teachers College
subject: Commencement ceremonies

description: Commencement program for August 27, 1943, which may include written corrections and annotations. While every effort is made to ensure accuracy in commencement programs, printing deadlines sometimes prevent inclusion of candidates' names or may result in the use of names of persons not completing graduation requirements.
TramLab Toolkit #4 Gender-sensitive Training
Creators: name: TramLab, TramLab
Publisher: name: Monash University
Year: 2022
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences

description: This toolkit is one of four designed by the TramLab team to help improve public transport safety for women and girls. Gender-sensitive training across all levels of public transport staff is essential to improving safety for women and girls on public transport. Consistently working to understand what women’s safety means across the sector supported by strong training will mitigate against abuses of power and improve reporting levels and responses.
title: Forty-Second Annual Commencement of the State Teachers College
title: Annual Commencement
titleType: AlternativeTitle
Creators: name: State Teachers College
Publisher: name: Maryland Shared Open Access Repository
Year: 1945
Subjects: subject: State Teachers College
subject: Commencement ceremonies

description: Commencement program for August 24, 1945, which may include written corrections and annotations. While every effort is made to ensure accuracy in commencement programs, printing deadlines sometimes prevent inclusion of candidates' names or may result in the use of names of persons not completing graduation requirements.