cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Geography textbook tasks fostering thinking skills for the acquisition of powerful knowledge
Creators: name: Krause, Uwe
name: Béneker, Tine
name: van Tartwijk, Jan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Plant Biology

description: Tasks are essential in fostering students’ learning processes, and thinking skills are considered to be of central importance to learning. In order to analyse how tasks promote the development of thinking skills in school geography, we need an instrument that looks beyond a simple distinction between lower and higher order thinking. It should be able to identify types of tasks based on distinctive elements on the way to acquiring powerful knowledge or knowledge of high epistemic quality. In this paper, we describe the development of an instrument based on the adaptation of existing categorisations and the use of Bernstein’s recognition and realisation rules. The instrument distinguishes five levels of thinking: lower order thinking, use of thinking strategies, parts of higher order thinking, higher order thinking, and reflection. The instrument was employed to analyse tasks in geography textbooks used in the Netherlands and the German State North Rhine-Westphalia, with researchers and teacher educators in both states considering its efficacy both plausible and practicable. The results show that the instrument is sufficiently sensitive to identify differences in types of tasks and the extent to which access to powerful knowledge is fostered.
Neutron-rich chromium isotope anomalies in supernova nanoparticles
Creators: name: Dauphas, Nicolas
name: Remusat, Laurent
name: Chen, James
name: Roskosz, Mathieu
name: Papanastassiou, Dimitri
name: Stodolna, Julien
name: Guan, Yunbin
name: Ma, Chi
name: Eiler, John
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Neutron-rich isotopes with masses near that of iron are produced in type Ia and II supernovae. Traces of such nucleosynthesis are found in primitive meteorites in the form of variations in the isotopic abundance of 54Cr, the most neutron-rich stable isotope of chromium. The hosts of these isotopic anomalies must be presolar grains that condensed in the outflows of supernovae, offering the opportunity to study the nucleosynthesis of iron-peak nuclei in ways that complement spectroscopic observations and can inform models of stellar evolution. However, despite almost two decades of extensive search, the carrier of 54Cr anomalies is still unknown, presumably because it is fine-grained and is chemically labile. Here we identify in the primitive meteorite Orgueil the carrier of 54Cr-anomalies as nanoparticles, most likely spinels that show large enrichments in 54Cr relative to solar composition (54Cr/52Cr ratio >3.6xsolar). Such large enrichments in 54Cr can only be produced in supernovae. The mineralogy of the grains supports condensation in the O/Ne-O/C zones of a type II supernova, although a type Ia origin cannot be excluded. We suggest that planetary materials incorporated different amounts of these nanoparticles, possibly due to late injection by a nearby supernova that also delivered 26Al and 60Fe to the solar system. This idea explains why the relative abundance of 54Cr and other neutron-rich isotopes vary between planets and meteorites. We anticipate that future isotopic studies of the grains identified here will shed new light on the birth of the solar system and the conditions insupernovae.
description: accepted for publication in the Astrophysical Journal; 41 pages, 13 figures, 4 tables
Additional file 13 of The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Creators: name: Grimes, Martha M.
name: S. Ray Kenney
name: Dominguez, Dayna R.
name: Brayer, Kathryn J.
name: Guo, Yuna
name: Wandinger-Ness, Angela
name: Hudson, Laurie G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 13: Figure S8. Raw images of western blot membranes used to detect Rho-GTPases in tumors from placebo and R-ketorolac treated mice. Membranes were cut between 25 and 37 kDa as guided using Precision Plus Protein Dual Color Standards (Bio-Rad Laboratories, Inc., cat# 1610374) before incubation with antibodies. This allowed probing of GAPDH (loading control) and the GTPase targets without a strip and re-probe procedure.
An interdisciplinary approach to address aquatic environmental issues with young students from Brazil
Creators: name: Scoarize, Matheus Maximilian Ratz
name: Contieri, Beatriz Bosquê
name: Delanira-Santos, Driele
name: Zanco, Bárbara Furrigo
name: Benedito, Evanilde
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology

description: Environmental education aims to change the perception of people about the environment. Primary education (four to eleven years old) is a fundamental stage in the development of children’s conduct, so enhancing learning of the environment in which they live is essential for them to start recognizing nature as part of their life. We tested students’ perception before (pre-test) and after (post-test) a specific environmental education activity elaborated in a ludic and interdisciplinary way (psychological, biological, performing arts and educational perspectives), with more moments of practice than only theoretical or rhetorical. Our study showed that schools located in cities with low Municipal Human Development Index (MHDI) can present satisfactory results in relation to students’ environmental perception (hypothesis 1), that this perception does not differ according to nationwide educational indexes such as the Brazilian Basic Education Development Index (IDEB) (2), and that regardless of MHDI, there is an increase in this perception after environmental education activities, even a single activity (3). The developed methodology was effective in changing students’ environmental perception, and can be used in an interdisciplinary way, even when resources are scarce.
The ‘Green Shadow’ : paradox of increasing green practices and stagnant labour conditions
Creators: name: Islam, Saima
Publisher: name: University of British Columbia
Year: 2023

description: The adoption of ‘green practices’ has gained momentum in the global supply chains, but in comparison there has been little improvement in terms of labour conditions and wages. This study explores why labour issues have made minimal progress while environmental regulations are gaining traction. Why do low wages and poor labour standards persist, while the adoption of green norms such as recycling, and energy efficiency has increased in global supply chains? To address these questions, I formulate my argument in two parts using the lens of ideas, interest and institutions: firstly, I argue that the global climate and environmental governance architecture has become more advanced and restrictive than the global labour governance architecture, generating push forces on states and direct pull forces on nonstate actors such as multinational corporations to voluntarily commit and adopt greener practices. Meanwhile, the labour governance architecture's ineffectiveness in restricting MNCs or persuading them to voluntarily commit to better working conditions has resulted in slower overall progress in advancing labour rights. Secondly, I argue that the outcome of this governance asymmetry between labour and environmental governance casts a “Green Shadow’ over labour conditions where MNCs and states disproportionately focus on greening the supply chains while sidelining labour issues in the process. Using the empirical case study of apparel or ready-made garments industry in Bangladesh, I find that there are primarily two kinds of governance influence that ‘push’ the state to alter local practices: directly setting conditions on the producing firms and influencing the domestic policies. While ‘pull’ MNCs and businesses to limit their ecological footprint. I argue that the climate governance architecture has managed to incorporate environmental norms into domestic decisions and preferences by engaging the state itself and through MNCs.
On transversally elliptic operators and the quantization of manifolds with $f$-structure
Creators: name: Fitzpatrick, Sean
Publisher: name: arXiv
Year: 2011
Subjects: subject: Differential Geometry (math.DG)
subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics
subject: 53D50 (Primary) 53C07, 53C15, 53C25, 32V05 (Secondary)

description: An $f$-structure on a manifold $M$ is an endomorphism field $ϕ\inΓ(M,\End(TM))$ such that $ϕ^3+ϕ=0$. Any $f$-structure $ϕ$ determines an almost CR structure $E_{1,0}\subset T_\C M$ given by the $+i$-eigenbundle of $ϕ$. Using a compatible metric $g$ and connection $\nabla$ on $M$, we construct an odd first-order differential operator $D$, acting on sections of $§=ΛE_{0,1}^*$, whose principal symbol is of the type considered in arXiv:0810.0338. In the special case of a CR-integrable almost $§$-structure, we show that when $\nabla$ is the generalized Tanaka-Webster connection of Lotta and Pastore, the operator $D$ is given by $D = \sqrt{2}(\dbbar+\dbbar^*)$, where $\dbbar$ is the tangential Cauchy-Riemann operator. We then describe two "quantizations" of manifolds with $f$-structure that reduce to familiar methods in symplectic geometry in the case that $ϕ$ is a compatible almost complex structure, and to the contact quantization defined in \cite{F4} when $ϕ$ comes from a contact metric structure. The first is an index-theoretic approach involving the operator $D$; for certain group actions $D$ will be transversally elliptic, and using the results in arXiv:0810.0338, we can give a Riemann-Roch type formula for its index. The second approach uses an analogue of the polarized sections of a prequantum line bundle, with a CR structure playing the role of a complex polarization.
description: 31 pages
High population-attributable fractions of traditional risk factors for non-AIDS-defining diseases among people living with HIV in China: a cohort study
Creators: name: Liu, Jiaye
name: Hou, Yuying
name: Sun, Liqin
name: Wang, Lifeng
name: He, Yun
name: Zhou, Yang
name: Xu, Liumei
name: Liu, Xiaoning
name: Zhao, Fang
name: Zhang, Lukun
name: Wang, Hui
name: Wang, Fu-Sheng
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Morbidity and mortality of non-AIDS-defining diseases (NADs) have become the increasing burden of people living with HIV (PLWH) with long-term antiretroviral therapy (ART). We aimed to quantify the contribution of modifiable risk factors to NADs. We included PLWHs starting ART at the Third People’s Hospital of Shenzhen (China) from Jan 1, 2010 to Dec 31, 2017. We defined NAD outcomes of interest as cardiovascular disease (CVD), end-stage liver disease (ESLD), advanced renal disease (ARD), and non-AIDS-defining cancers (NADCs). We estimated incidence of outcomes and population-attributable fractions (PAFs) of modifiable traditional and HIV-related risk factors for each outcome. Overall, 8,301 participants (median age at study entry, 31 years) contributed 33,146 person-years of follow-up (PYFU). Incidence of CVD (362/100,000 PYFU) was the highest among outcomes, followed by that of ARD (270/100,000 PYFU), ESLD (213/100,000 PYFU), and NADC (152/100,000 PYFU). Totally, 34.14% of CVD was attributable to smoking, 7.98% to hypertension, and 6.44% to diabetes. For ESLD, 24.57% and 25.04% of it could be avoided if chronic hepatitis B and C virus infection, respectively, did not present. The leading PAFs for ARD were declined estimated glomerular filtration rate (eGFR) (39.68%) and low CD4 count (39.61%), followed by diabetes (10.19%). PAFs of hypertension, diabetes, and smoking for CVD, and declined eGFR and diabetes for ARD increased with age. The contribution of traditional risk factors for these NADs far outweighed the HIV-related risk factors. Individual-level interventions and population-level policy-making is needed to focus on these factors to prevent NADs in long-term management of HIV infection.
Intermediate range migration in the two-dimensional stepping stone model
Creators: name: Cox, J. Theodore
Publisher: name: arXiv
Year: 2010
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: We consider the stepping stone model on the torus of side $L$ in $\mathbb{Z}^2$ in the limit $L\to\infty$, and study the time it takes two lineages tracing backward in time to coalesce. Our work fills a gap between the finite range migration case of [Ann. Appl. Probab. 15 (2005) 671--699] and the long range case of [Genetics 172 (2006) 701--708], where the migration range is a positive fraction of $L$. We obtain limit theorems for the intermediate case, and verify a conjecture in [Probability Models for DNA Sequence Evolution (2008) Springer] that the model is homogeneously mixing if and only if the migration range is of larger order than $(\log L)^{1/2}$.
description: Published in at http://dx.doi.org/10.1214/09-AAP639 the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Additional file 9 of The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Creators: name: Grimes, Martha M.
name: S. Ray Kenney
name: Dominguez, Dayna R.
name: Brayer, Kathryn J.
name: Guo, Yuna
name: Wandinger-Ness, Angela
name: Hudson, Laurie G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 9: Figure S4. HIF-1 Signaling Pathway as defined in the KEGG Pathway database. Highlighted are the differentially expressed genes found in the tumors isolated from R-ketorolac treated mice compared to placebo control when aligned to the human genome. Color key in upper right of figure indicates shading for up (red) and down (blue) regulated genes.
Hydrodynamic flow in heavy-ion collisions with large hadronic viscosity
Creators: name: Shen, Chun
name: Heinz, Ulrich W
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Using the (2+1)-dimensional viscous hydrodynamic code VISH2+1 with a temperature dependent specific shear viscosity (eta/s)(T), we present a detailed study of the influence of a large hadronic shear viscosity and its corresponding relaxation time tau_pi on the transverse momentum spectra and elliptic flow of hadrons produced in 200 A GeV Au+Au collisions. Although theory, in principle, predicts a well-defined relation T*tau_pi = kappa(T)*(eta/s)(T), the precise form of kappa(T) for the matter created in relativistic heavy-ion collisions is not known. For the popular choice kappa=3 the hadron spectra are found to be insensitive to a significant rise of eta/s in the hadronic stage, whereas their differential elliptic flow v_2(p_T) is strongly suppressed by large hadronic viscosity. The large viscous effects on v_2 are strongly reduced if (as theoretically expected) kappa(T) is allowed to grow with decreasing temperature in the hadronic stage. This implies that, until reliable calculations of kappa(T) become available, an extraction of the hadronic shear viscosity from a comparison between VISH2+1 and a microscopic hadron cascade or experimental data requires a simultaneous fit of (eta/s)(T) and kappa(T).
description: 12 pages, 10 figures, submitted to Physical Review C. Parts of abstract and introduction, as well as all of Sec. VI, have been rewritten for v2. v2 uses a more realistic toy model for kappa(T) than v1, and all results obtained with the earlier model have been replaced (but are still available at http://arxiv.org/abs/1101.3703v1). No change to conclusions
Additional file 6 of The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Creators: name: Grimes, Martha M.
name: S. Ray Kenney
name: Dominguez, Dayna R.
name: Brayer, Kathryn J.
name: Guo, Yuna
name: Wandinger-Ness, Angela
name: Hudson, Laurie G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 6: Table S2. topGO Categories against the Human Genome.
Additional file 14 of The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Creators: name: Grimes, Martha M.
name: S. Ray Kenney
name: Dominguez, Dayna R.
name: Brayer, Kathryn J.
name: Guo, Yuna
name: Wandinger-Ness, Angela
name: Hudson, Laurie G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 14: Figure S9. Expression of select genes showing reciprocal regulation between Rac1 over-expressing cells (SKOV3ip-GFP-Rac1) and tumors from R-ketorolac treated mice. (A) Western blot verification of Rac1 over-expressed protein of SKOV3ip-GFP-Rac1 cells relative to SKOV3ip-GFP only cells. Total Rac1 protein was normalized to GAPDH loading control. This data is from two separate experiments and was compared using unpaired t-test. (B) Gene expression levels in SKOV3ip-GFP-Rac1 cells of HMOX-1, CXCR4, VEGF-A and HIF1-α were measured by qPCR as described in Methods. These data are combined from three separate experiments. They were compared to SKOV3ip-GFP and normalized to 18 s rRNA using unpaired two tailed t-test. (C) Gene expression levels of CXCR4 and HIF1-α from tumors obtained from placebo control and R-ketorolac treated mice were determined by qPCR as described in Methods. Values are combined from three separate experiments and represent relative expression for R-ketorolac compared to placebo (1.0). Values were also normalized to 18 s rRNA and analyzed using unpaired two tailed t-test. For all panels * indicates p-value ≤0.05 ** indicates p-value ≤0.01 and **** indicates p-value ≤0.0001.
Sozial-kommunikativer Nutzen der elektronischen Sprachausgabegeräte in der UK Inwiefern verändert die Nutzung eines elektronischen Sprachausgabegeräts die Interaktion eines Nutzers mit seinem Umfeld?
Creators: name: Gugger Reichmuth, Barbara
Publisher: name: Zenodo
Year: 2016
Subjects: Logopädie
Kommunikationshilfe
Bachelorarbeit

description: Von allen uns zur Verfügung stehenden Kommunikationsmitteln verwenden wir die gesprochene Sprache am meisten. Was aber, wenn diese verbale Möglichkeit der Aufnahme und der Aufrechterhaltung des Kontaktes mit der sozialen Umwelt nicht oder nur begrenzt zur Verfügung steht? Und inwiefern verändert die Nutzung eines elektronischen Sprachausgabegeräts die Interaktion des Nutzers mit seinem Umfeld? Um eine Antwort auf diese Fragen zu finden, wurden mit drei Erhebungsinstrumenten Daten von zwei Kindern und einem Jugendlichen mit Sprach- und Sprecheinschränkungen sowie von ihren Eltern und je einer therapeutischen Fachperson erhoben und mittels qualitativer Inhaltsanalyse ausgewertet. Die anhand von sieben Themenbereichen diskutierten Daten haben gezeigt, dass die Nutzung eines elektronischen Sprachausgabegeräts die Interaktion eines Nutzers mit seinem Umfeld vereinfacht und neue, zahlreichere Interaktionsgelegenheiten ermöglicht.
Broad Brush Cosmos
Creators: name: Carilli, Chris L.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: An innovative approach to map the large-scale structure in the Universe sidesteps the conventional need to observe millions of galaxies individually, and holds promise for both astrophysical and cosmological studies.
description: Invited Nature 'News and Views' Commentary on Chang et al. 2010, Nature, 466, 463; 6pages, 1 figure
Second-position clitics, from morphosyntax to semantics : the ʔayʔaǰuθəm (Comox-Sliammon) perspective
Creators: name: Huijsmans, Marianne
Publisher: name: University of British Columbia
Year: 2023

description: In this dissertation, I examine the second-position clitic system in ʔayʔaǰuθəm, a Central Salish language traditionally spoken along the northern Georgia Strait in British Columbia. The system includes subject agreement markers, modals, evidentials, discourse particles, and a scalar exclusive. I examine both the morphosyntax of these clitics and their semantic contributions. This dissertation has three parts. In Part I, I argue that the clitics occupy a series of functional heads above the verb phrase. When linearized, however, they occur in ‘second position’, following the first word of the verb phrase. Based on evidence from coordinate structures, I argue that the clitics’ host does not move above the clitics, since doing so would violate the Coordinate Structure Constraint. Instead, I argue that the clitics are lexically specified as enclitics and linearized with respect to their host in the morphology, following the first morphosyntactic stage of a two-stage lexical insertion operation. The morphological unit consisting of the clitic string and its host then serves as the input to a second morphophonological stage of lexical insertion, accounting for a range of allomorphy effects. In Part II, I examine the semantics of modal and evidential enclitics. I argue that two indirect evidentials, a reportative and an inferential, are strong epistemic modals. These contrast with two direct evidentials, labelled clausal demonstratives because they involve spatio-temporal deixis, which test as non-modal. I also propose a unified analysis for the future enclitic, which is used to make both claims about the future and inferences about past and present eventualities, and extend the analysis to English will. In Part III, I examine a variety of discourse-sensitive enclitics. I provide an analysis of the domain widening effect of a scalar exclusive particle when it associates with universally quantified phrases. I also discuss three discourse particles with contributions relating to common ground management, discourse coherence, and speaker commitment. This dissertation represents the first comprehensive analysis of the second-position clitic system in a Salish language. As such, it contributes both to the documentation of an endangered language and to the theoretical literature on the morphology, syntax, and semantics of second-position clitics.
Additional file 2 of The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Creators: name: Grimes, Martha M.
name: S. Ray Kenney
name: Dominguez, Dayna R.
name: Brayer, Kathryn J.
name: Guo, Yuna
name: Wandinger-Ness, Angela
name: Hudson, Laurie G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 2: Figure S1. Enantiomer stability of ketorolac in the oral dosage form. Percent of each ketorolac enantiomer was determined by HPLC as described in Supplemental Methods (Additional File 1: Supplemental Methods). Analysis was conducted after pill storage at 4 °C for three months. Data presented are the average values from two pills.
Wien2wannier: From linearized augmented plane waves to maximally localized Wannier functions
Creators: name: Kunes, Jan
name: Arita, Ryotaro
name: Wissgott, Philipp
name: Toschi, Alessandro
name: Ikeda, Hiroaki
name: Held, Karsten
Publisher: name: arXiv
Year: 2010
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present an implementaion of interface between the full-potential linearized augmented plane wave package Wien2k and the wannier90 code for the construction of maximally localized Wannier functions. The FORTRAN code and a documentation is made available and results are discussed for SrVO$_3$, Sr$_2$IrO$_4$ (including spin-orbit coupling), LaFeAsO, and FeSb$_2$.
description: 15 pages, 9 figures
HAT-P-27b: A hot Jupiter transiting a G star on a 3 day orbit
Creators: name: Béky, Bence
name: Bakos, Gáspár Á.
name: Hartman, Joel
name: Torres, Guillermo
name: Latham, David W.
name: Jordán, Andres
name: Arriagada, Pamela
name: Bayliss, Daniel
name: Kiss, László L.
name: Kovács, Géza
name: Quinn, Sam N.
name: Marcy, Geoffrey W.
name: Howard, Andrew W.
name: Fischer, Debra A.
name: Johnson, John A.
name: Esquerdo, Gilbert A.
name: Noyes, Robert W.
name: Buchhave, Lars A.
name: Sasselov, Dimitar D.
name: Stefanik, Robert P.
name: Perumpilly, Gopakumar
name: Lázár, József
name: Papp, István
name: Sári, Pál
Publisher: name: arXiv
Year: 2011
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report the discovery of HAT-P-27b, an exoplanet transiting the moderately bright G8 dwarf star GSC 0333-00351 (V=12.214). The orbital period is 3.039586 +/- 0.000012 d, the reference epoch of transit is 2455186.01879 +/- 0.00054 (BJD), and the transit duration is 0.0705 +/- 0.0019 d. The host star with its effective temperature 5300 +/- 90 K is somewhat cooler than the Sun, and is more metal-rich with a metallicity of +0.29 +/- 0.10. Its mass is 0.94 +/- 0.04 Msun and radius is 0.90 +/- 0.04 Rsun. For the planetary companion we determine a mass of 0.660 +/- 0.033 MJ and radius of 1.038 +0.077 -0.058 RJ. For the 30 known transiting exoplanets between 0.3 MJ and 0.8 MJ, a negative correlation between host star metallicity and planetary radius, and an additional dependence of planetary radius on equilibrium temperature are confirmed at a high level of statistical significance.
description: Submitted to ApJ on 2011-01-18. 12 pages, 7 figures, 7 tables
Effective-mass Klein-Gordon Equation for non-PT/non-Hermitian Generalized Morse Potential
Creators: name: Arda, Altug
name: Sever, Ramazan
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The one-dimensional effective-mass Klein-Gordon equation for the real, and non-\textrm{PT}-symmetric/non-Hermitian generalized Morse potential is solved by taking a series expansion for the wave function. The energy eigenvalues, and the corresponding eigenfunctions are obtained. They are also calculated for the constant mass case.
description: 14 pages
Symmetry breaking of optical vortices: Birth and annihilation of singularities in the evanescent field
Creators: name: Brandão, P. A.
name: Julião, C. J. S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Optics (physics.optics)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The interaction of optical vortices (or phase singularities, screw dislocations) with ordinary matter is treated with simple approach. Using total internal reflection phenomenon and superposition of four plane waves incident on a material with refractive index lower than the original propagating medium, we are able to show birth and annihilation of optical vortices in the evanescent field with curved topological features. Until now, this phenomenon has been explored only in free space propagation. By a suitable tuning process, involving the incident angles and the amplitudes of the incident plane waves, it is possible to create unusual topological features of optical vortices in the vicinity of the material. We believe that this work can open new aspects of curved optical vortex manipulation in near-field optics.
Magnetic transition and spin fluctuations in the unconventional antiferromagnetic compound Yb3Pt4
Creators: name: Zhao, S.
name: MacLaughlin, D. E.
name: Bernal, O. O.
name: Mackie, J. M.
name: Marques, C.
name: Janssen, Y.
name: Aronson, M. C.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Muon spin rotation and relaxation measurements have been carried out on the unconventional antiferromagnet Yb_3Pt_4. Oscillations are observed below T_N = 2.22(1) K, consistent with the antiferromagnetic (AFM) Neel temperature observed in bulk experiments. In agreement with neutron diffraction experiments the oscillation frequency omega_ mu(T) follows a S = 1/2 mean-field temperature dependence, yielding a quasistatic local field 1.71(2) kOe at T = 0. A crude estimate gives an ordered moment of ~0.66 mu_B at T = 0, comparable to 0.81 mu_B from neutron diffraction. As T approaches T_N from above the dynamic relaxation rate lambda_d exhibits no critical slowing down, consistent with a mean-field transition. In the AFM phase a T-linear fit to lambda_d(T), appropriate to a Fermi liquid, yields highly enhanced values of lambda_d/T and the Korringa constant K_ mu^2 T/lambda_d, with K_ mu the estimated muon Knight shift. A strong suppression of lambda_d by applied field is observed in the AFM phase. These properties are consistent with the observed large Sommerfeld-Wilson and Kadowaki-Woods ratios in Yb_3Pt_4 (although the data do not discriminate between Fermi-liquid and non-Fermi-liquid states), and suggest strong enhancement of q ~ 0 spin correlations between large-Fermi-volume band quasiparticles in the AFM phase of Yb_3Pt_4.
description: 11 pages, 4 figures, submitted to J. Phys.: Condens. Matter special issue for SCES10
Additional file 3 of The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Creators: name: Grimes, Martha M.
name: S. Ray Kenney
name: Dominguez, Dayna R.
name: Brayer, Kathryn J.
name: Guo, Yuna
name: Wandinger-Ness, Angela
name: Hudson, Laurie G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 3: Table S1. Omental Weight.
Additional file 7 of The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Creators: name: Grimes, Martha M.
name: S. Ray Kenney
name: Dominguez, Dayna R.
name: Brayer, Kathryn J.
name: Guo, Yuna
name: Wandinger-Ness, Angela
name: Hudson, Laurie G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 7: Table S3. topGO Categories against the Mouse Genome.
The targum (1966:May 02 - 1966:May 6)
Creators: name: No Name Supplied
Publisher: name: Targum Association
Year: 1966

description: Some University historians indicate that the Targum was first published as an annual in 1867, but of this we have no extant evidence. In January 1869, the Targum as we now know it, made its appearance as a monthly paper that concerned itself with student “literary contributions” and college news as well as serving as a vehicle for bringing news to alumni and the general public. The newspaper, which originally was for sale, varied in frequency over the years as did its title (The Targum, Rutgers Targum, Rutgers Daily Targum, and Daily Targum). The newspaper has continuously been published since 1869 with the exception of 19 months during the second world war, between February 1944 and October 1945. The Targum was published by the students of Rutgers College, and later Rutgers University—New Brunswick represented through the years as the Targum Association, Rutgers Targum Association, and Rutgers College Targum. As a student organization, the Targum operated under the oversight of the dean of students and student government but in October 1980, the Targum became an independent college paper.
Additional file 12 of The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Creators: name: Grimes, Martha M.
name: S. Ray Kenney
name: Dominguez, Dayna R.
name: Brayer, Kathryn J.
name: Guo, Yuna
name: Wandinger-Ness, Angela
name: Hudson, Laurie G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 12: Figure S7. Expression of COX1 and COX2 in tumors from placebo, R-ketorolac, S-ketorolac, and racemic ketorolac (R−/S-) treated mice (all 1 mg/kg twice daily). (A) Gene expression levels of COX1 and COX2 were measured by qPCR as described in Methods. These data are combined from three separate experiments, n = 12. ** indicates p-value ≤0.01 and **** indicates p-value ≤0.0001 when compared to tumors of placebo mice and normalized to 18 s rRNA using one-way ANOVA, followed by Dunnett’s multiple comparisons test. (B) COX1 and COX2 protein levels were decreased with S-ketorolac or R−/S-ketorolac treatment, yet unaffected by R-ketorolac treatment. Tumor protein was isolated from placebo, R-ketorolac, S-ketorolac, or R−/S-ketorolac treated mice and analyzed by western blot analysis as described in Supplemental Methods (Additional File 1: Supplemental Methods). Representative blots from one of two independent experiments are shown. GAPDH served as the loading control.
Static Observers in Curved Spaces and Non-inertial Frames in Minkowski Spacetime
Creators: name: Dahia, F.
name: da Silva, P. J. Felix
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Static observers in curved spacetimes may interpret their proper acceleration as the opposite of a local gravitational field (in the Newtonian sense). Based on this interpretation and motivated by the equivalence principle, we are led to investigate congruences of timelike curves in Minkowski spacetime whose acceleration field coincides with the acceleration field of static observers of curved spaces. The congruences give rise to non-inertial frames that are examined. Specifically we find, based on the locality principle, the embedding of simultaneity hypersurfaces adapted to the non-inertial frame in an explicit form for arbitrary acceleration fields. We also determine, from the Einstein equations, a covariant field equation that regulates the behavior of the proper acceleration of static observers in curved spacetimes. It corresponds to an exact relativistic version of the Newtonian gravitational field equation. In the specific case in which the level surfaces of the norm of the acceleration field of the static observers are maximally symmetric two-dimensional spaces, the energy-momentum tensor of the source is analyzed.
description: 28 pages, 4 figures.
Additional file 4 of The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Creators: name: Grimes, Martha M.
name: S. Ray Kenney
name: Dominguez, Dayna R.
name: Brayer, Kathryn J.
name: Guo, Yuna
name: Wandinger-Ness, Angela
name: Hudson, Laurie G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 4: Figure S2. Expression of Rho-GTPases in tumors from placebo, R-ketorolac, S-ketorolac, and racemic ketorolac (R−/S-) treated mice. (A) Gene expression levels of RAC1, CDC42 and RHOA were measured by qPCR as described in Methods. These data are combined from three separate experiments with a total of 12 mice. * indicates p-value ≤0.05 and ** indicates p-value ≤0.01 when compared to tumors of placebo mice and normalized to 18 s rRNA using one-way ANOVA, followed by Dunnett’s multiple comparisons test. (B) Western blot analysis of Rac1, Cdc42, and RhoA tumor protein levels as described in Supplemental Methods (Additional File 1: Supplemental Methods). GAPDH served as the loading control. Normalized values for R-ketorolac vs placebo (1.0) are Rac1 0.83, Cdc42 0.72 and RhoA 0.70 for bands detected by the respective mouse monoclonal antibodies. These are cropped images from the original western blots (Additional File 13: Figure S8). (C) To more specifically investigate the potential of R-ketorolac to modulate GTPase protein expression without potential interference of the mouse monoclonal antibodies reacting with mouse protein in the lysate, three independent cultures of SKOV3ip-GFP cells used for the xenografts were treated with 30 μM R-ketorolac for 5 days in culture. No significant differences in GTPase expression were detected as a consequence of R-ketorolac treatment.
Additional file 5 of The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Creators: name: Grimes, Martha M.
name: S. Ray Kenney
name: Dominguez, Dayna R.
name: Brayer, Kathryn J.
name: Guo, Yuna
name: Wandinger-Ness, Angela
name: Hudson, Laurie G.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 5: Figure S3. Heat map of 149 differentially expressed genes in tumors isolated from placebo versus R-ketorolac treated mice when aligned to mouse genome. Differentially expressed genes are labeled on the right and sample designations are labeled on the top. Color key in upper left indicates shading for up (red) and down (blue) regulated genes. Dendrograms at the top and side indicate relationship between the samples and differentially expressed genes, respectively. The color bar at the top indicates the sample conditions, R-ketorolac (red) and Placebo (black).
title: Regional Invasive Species & Climate Change Management Challenge: Embracing the Future. Promoting adaptation and resilience to invasive species and climate change
Creators: name: Lopez, Bianca
name: Brown-Lima, Carrie
name: Dalaba, Justin
name: Evans, Annette
name: Graham MacLean, Meghan
name: Morelli, Toni Lyn
Publisher: name: University of Massachusetts Amherst
Year: 2021

description: Climate change and invasive species can interact to increase disturbances and magnify changes in ecosystem form and function (Double Trouble). Increasing resilience is one of several management approaches for enabling healthy ecosystems to persist despite these changes. While resilience can be complicated and take many forms, it can generally be thought of as the “ability [of an ecosystem] to experience disturbances or environmental change without changing to a fundamentally different state” [Holling, 1973].

The accumulating effects of climate change, invasive species, or interacting effects of multiple disturbances can push an ecosystem past a tipping point and into a new ecological state. These alternative states are characterized by a different suite of species or functions, which are difficult or impossible to recover from (e.g. a shift from a closed-canopy to an open-canopy forested wetland). Actions to increase resilience help an ecosystem to maintain or return to its fundamental structure or function after a disturbance.

Resilience falls in the middle of a spectrum of management goals ranging from preventing change (resistance) to promoting change (transformation) in the species composition, structure, or functions provided by an ecosystem. Clear management goals (See Table) and an understanding of the range of disturbances affecting focal ecosystems are necessary for deciding between managing for resistance, resilience, or transformation and what actions are required for successful management outcomes.
Dark Energy Model in Anisotropic Bianchi Type-III Space-Time with Variable EoS Parameter
Creators: name: Pradhan, Anirudh
name: Amirhashchi, Hassan
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: A new dark energy model in anisotropic Bianchi type-III space-time with variable equation of state (EoS) parameter has been investigated in the present paper. To get the deterministic model, we consider that the expansion $θ$ in the model is proportional to the eigen value $σ^{2}_{~2}$ of the shear tensor $σ^{j}_~i$. The EoS parameter $ω$ is found to be time dependent and its existing range for this model is in good agreement with the recent observations of SNe Ia data (Knop et al. 2003) and SNe Ia data with CMBR anisotropy and galaxy clustering statistics (Tegmark et al. 2004). It has been suggested that the dark energy that explains the observed accelerating expansion of the universe may arise due to the contribution to the vacuum energy of the EoS in a time dependent background. Some physical aspects of dark energy model are also discussed.
description: 18 pages, 3 figures
Addressing reproducibility in deep learning medical image segmentation methods through the PCS framework
Creators: name: Porisky, Adam
Publisher: name: University of British Columbia
Year: 2023

description: Medical image segmentation is an essential part of a many healthcare services. While it is possible for an expert to manually label each pixel or voxel in an image, it is a time-consuming process that lacks reproducibility and doesn’t scale well — a problem that will only get worse as advancements in medical image acquisition yield greater quantities of images with higher resolution. To address this need, automatic deep learning-based segmentation has become a popular research direction. However, due to their complexity, deep learning solutions have a high level of variability both in terms of design and outcomes. In this thesis we present a workflow that leverages the core principles of the PCS framework, an existing set of data science recommendations, to improve the reproducibility and transparency of deep learning medical image segmentation results. We started with a conventional approach for comparison, evaluating the impact of the network depth, filter sizes, and presence of shortcut connections on a convolutional encoder network. We found shortcuts to have the greatest impact (DSC 0.20), while changes to the filter size (DSC 0.04) and the number of layers (DSC 0.03) also affected performance. We then implemented our proposed workflow, incorporating PCS principles, to evaluate the predictability of a broader range of convolutional encoder network architecture and algorithm variations, as well as characterize the performance of those models under reasonable perturbations. By exploring variations in loss functions, filter size, and hidden unit quantity as model perturbations, we determined a subset of models that met a standard of predictability. All of our selected model perturbations performed comparably well in terms of predictability (DSC [0.79 - 0.80]). Stability analysis of these models demonstrated poor hyper-parameter stability when using the sensitivity-specificity ratio as a loss function, and improved stability and distance-based metric performance for 5 x 5 filters. The additional information provided as a result of using our workflow directly improves upon the recommendations derived from the conventional approach.
The Legacy of Slavery: A 19th Century Newspaper and 21st Century Racial Inequity
Creators: name: Jevon, Graham
Publisher: name: British Library
Year: 2020
Subjects: Barbados
colonialism
Americas
empire
newspapers
Christianity
resistance
racism
slavery
British Empire
Caribbean
digital images

description: This blog post introduces a newly digitised collection of 18th/19th century Barbadian newspapers and commented on the slavery related content of these newspapers within the context of 21st century racism.
description: UK
The role of growth hormone device optimization in patient-reported outcomes: real-world evidence from South Korea
Creators: name: Lee, Ji-Eun
name: Lee, Kee-Hyoung
name: Park, Mi Jung
name: Yang, Seung
name: Kim, Eun Young
name: Rhie, Young-Jun
name: Jung, Min-Ho
name: Yang, Aram
name: Kim, Shin-Hye
name: Chung, Lindsey Yoojin
name: Ko, Su Young
name: Lee, Young Ju
name: Nedjatian, Navid
name: Chung, Woo Yeong
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Growth hormone (GH) treatment preference and adherence are affected by delivery device convenience, injection-site pain, confidence in correct dose administration, and device satisfaction. This survey investigated if switching device to NordiFlex® improved treatment experience in pediatric patients in South Korea. Patients aged 4–≤18 years were surveyed. Participants were NordiFlex® users who previously used NordiLet®/other devices. Participants compared preference, self-reported adherence, satisfaction, perceived ease of use, and device subjective benefits (across four domains: ease of use, self-efficacy, minimal disruption of daily life, positive feelings about injections) of NordiFlex® vs. previous device. Ninety-four patients were enrolled, of which 91.5% previously used NordiLet®. Significantly more patients preferred, and were more satisfied with NordiFlex® vs. previous device; mean score: 0.65 (95% confidence interval [CI]:0.41;0.88) and 0.61 (95% CI:0.36;0.85), respectively. Participants reported greater perceived ease of use (0.49 [95% CI:0.26;0.72]) and fewer missed injections (0.20 [95% CI:0.06;0.34], with NordiFlex® vs. previous device. Bivariate analysis showed significant associations between preference for NordiFlex® and higher scores on self-efficacy, ease of use, minimal disruption of daily life, and positive feelings about injection (all p < 0.001). These results suggest that improvements in device features could be associated with improved treatment experience.