cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Altitude isotope effects in Mediterranean high-relief terrains: a correction method to utilize stream water data
Creators: name: Hemmerle, H.
name: van Geldern, R.
name: Juhlke, T. R.
name: Huneau, F.
name: Garel, E.
name: Santoni, S.
name: Barth, J. A. C.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: Plant Biology

description: Quantification of the isotope altitude effect from precipitation allows the identification of recharge altitudes in high-relief areas. However, steep terrains frequently limit the use of this precipitation-based approach. Perennial rivers often provide easy, year-round access for water sampling. However, in high-relief regions rivers may not adequately represent regional precipitation isotope patterns because they integrate isotope signals along their course. This prevents the calculation of an altitudinal isotope gradient from river water samples alone. We present a study that shows how a river-based sampling approach served to determine the altitude effect. Replacing the original sample site altitude with the mean upstream catchment elevation as calculated from a digital elevation model allowed us to establish a plausible altitude isotope effect from stream water. The correction approach was verified independently using precipitation isotope data. This approach can potentially be transferred to other regions where precipitation sampling at various elevations is difficult to determine.
A Teoria Discursiva o Debate da Judicializa�ao da Sa�de No Brasil - Uma an�lise sobre a questao dos medicamentos.
Creators: name: ROVANI, ANATERCIA
Publisher: name: Universit� degli Studi di Milano
Year: 2016

description: O presente trabalho busca analisar o fen�meno da judicializa��o das pol�ticas p�blicas no Estado Democr�tico de Direito brasileiro por meio da an�lise dos processos judiciais em que o objeto da demanda � o pedido de medicamentos ao Estado. A escolha do tema tem origem na percep��o sobre o grande n�mero de processos judiciais ingressados com o objeto de requerer o fornecimento de medicamentos pelo Estado na �ltima d�cada. O direito � sa�de, portanto, � tema central da pesquisa, portanto, a defini��o desse direito � apresentada no in�cio no trabalho. Nesse sentido, o grau de alcance e prote��o desse direito depende da no��o de Estado escolhida pela sociedade, dessa maneira, necess�rio compreender a forma��o do Estado brasileiro em rela��o ao pacto constitucional de 1988. No contexto do Estado apresentado, adentra-se ao tema da judicializa��o da pol�tica tendo como base o princ�pio da divis�o de poderes. Defende-se o fen�meno da judicializa��o como a car�ncia da sociedade de um meio democr�tico para debater problemas na prote��o de seu direito. Apresenta-se como meio de minimaliza��o do problema o estabelecimento de meios de participa��o no qual o indiv�duo contribua na forma��o das normas que regem sua vida e que determinam sua autonomia. Por meio da revis�o de literatura consultada, analisa-se a possibilidade do judici�rio em exercer controle sobre as pol�ticas p�blicas de responsabilidade do Poder Executivo. A prote��o � sa�de p�blica, por seu car�ter de direito fundamental social, exige presta��es positivas do Estado na forma de pol�ticas p�blicas efetivas de fornecimento de medicamento. A n�o efetiva��o dessa condi��o gera a possibilidade do judici�rio interferir na pol�tica p�blica e exigir do Estado o cumprimento do dever constitucional. Analisa-se o car�ter social da necessidade de medicamentos e dos custos sociais ? n�o apenas econ�micos ? do descaso do Estado para com a prote��o da sa�de. Por fim, realizou-se uma an�lise emp�rica de decis�es proferidas pelo Supremo Tribunal Federal brasileiro entre os anos de 2000 a 2012, assim como das demandas sobre pedidos de fornecimento de medicamento para o Estado e das decis�es proferidas pelo judici�rio estadual do Rio Grande do Sul, ambas no per�odo de 01/01/2000 a 01/01/2013.
title: Exploiting ACC vehicles for improved traffic flow on motorways
title: Αξιοποίηση των ACC οχημάτων για την βελτίωση των κυκλοφοριακών συνθηκών σε αυτοκινητοδρόμους
Creators: name: Βανδωρου Φωτεινη
Publisher: name: Technical University of Crete
Year: 2018

description: Traffic congestion is a severe problem which has emerged due to the continuously increasing number of vehicles on motorways in many countries. In most cases, the construction of new transport infrastructure is not an option. In order to improve the traffic conditions on motorways, research has been performed on intelligent transportation systems. An aspect of these systems are Adaptive Cruise Control (ACC) Systems, which are, at present, mainly designed to increase the driving safety and comfort.
This thesis presents an ACC-based traffic control strategy, which aims to adapt in real time the driving behavior of ACC-equipped vehicles to the prevailing traffic conditions so as to increase traffic flow efficiency if and where needed. The ACC system acts automatically and adjusts the vehicle’s acceleration or deceleration so as to maintain either the desired maximum speed or the desired time-gap to the leading vehicle. The proposed control concept receives real-time traffic measurements from motorway sections and suggests to the drivers, or imposes directly, appropriate values for the time gap and modified acceleration dynamics, within acceptable safety limits. It should be stressed that the strategy intervenes only when needed, i.e. only when the motorway traffic flow efficiency needs to be improved so as to avoid or mitigate congestion. While demonstrating the potential benefits that may arise by applying the proposed control concept, different ACC penetration rates are used. Microscopic simulation is applied to a real motorway stretch (Motorway A20 in The Netherlands) where recurrent traffic congestion is created under the current manual-driving conditions due to an on-ramp bottleneck.
The simulation results demonstrate that for various, even low, penetration rates of ACC-vehicles, the proposed control concept improves the traffic conditions in general. Specifically, the average vehicle delay and the total fuel consumption have lower values compared to the case of only manually-driven or regular ACC-vehicles. This improvement is achieved by retarding the onset and reducing the space-time extent of the congestion in comparison to the no control case.
title: Μηχανικές διαμορφώσεις συμπαγών υλικών και επίπεδων ελασμάτων
Creators: name: Μαθιουλακη Κυριακη-Ευαγγελια
Publisher: name: Technical University of Crete
Year: 2018

description: Οι κατεργασίες διαμόρφωσης αποτελούν διαδικασίες κατά τις οποίες μορφοποιούνται υλικά και ανάλογα με τις ιδιότητες τους παραμορφώνονται πλαστικά παράλληλα με τη διατήρηση της μάζας τους, κάτω από συγκεκριμένες συνθήκες ταχύτητας, θερμοκρασίας πίεσης καθώς και άλλων παραγόντων.
Στη συγκεκριμένη εργασία μελετήθηκαν και παρουσιάζονται οι κατεργασίες πλαστικής παραμόρφωσης των μετάλλων που εντάσσονται στις κατεργασίες διαμόρφωσης. Γίνεται πλήρης παρουσίαση των κατεργασιών αυτών καθώς επίσης παρατίθενται ασκήσεις μέσα από τις οποίες διαφαίνεται η επίδραση των  χαρακτηριστικών των μετάλλων στη τελική μορφή των αντικειμένων .
EFFECT OF DIFFERENT IN VITRO ANTICOAGULANTS ON LABORATORY MEASUREMENT OF PLATELET FUNCTION
Creators: name: GERMANOVICH, KSENIA
Publisher: name: Universit� degli Studi di Milano
Year: 2015

description: Light transmission aggregometry (LTA) is commonly applied in the diagnosis of platelet bleeding disorders and in the research setting to monitor platelet function in the evaluation and development of antiplatelet agents. The guidelines for the standardisation of LTA for the study of platelet aggregation (PA) published in 2013 by the SSC-ISTH were largely based on the consensus of experts, because methodological studies directly comparing different procedures were lacking. We tested the cogency of some SSC-ISTH recommendations: 1) buffered citrate (109 or 129 mM) should be used as anticoagulant to help keep the pH stable; 2) after centrifugation, platelet-rich plasma (PRP) should sit at room temperature for 15 min before testing; 3) LTA studies should be completed within a maximum of 4h after blood sampling. Blood from 10 healthy volunteers was collected into buffered and non-buffered citrate (109 and 129 mM). PA was measured by LTA in PRP stimulated by ADP (2 ?M) immediately after preparation, 15 min thereafter (=1h after blood sampling), 2, 3 and 4h after blood sampling. Plasma pH and platelet count were measured at the same time points as LTA. PA changed within the first 15 minutes after PRP preparation, then remained stable up to 2h after blood sampling, and decreased thereafter; 2) PA tended to be higher in 109 mM than in 129 mM citrate; 3) there was no difference in PA between buffered and non-buffered citrate; 4) pH in buffered samples was lower than in non-buffered samples, but increased in all samples to pH 8 at 4h; 5) platelet count in non-buffered citrate PRP was lower than in buffered citrate and decreased over time in all samples. The loss of platelets was inhibited by addition of prostaglandin E1 (PGE1, 2 ?M) to whole blood upon collection. We conclude that PRP should rest for 15 min before testing; buffering of citrate does not affect PA significantly but does affect platelet count: therefore, it is uncertain whether the use of buffered citrate is preferable over non-buffered citrate; LTA studies should be completed within 2h rather than 4h after blood sampling.
title: Συγκριτική πολυκριτήρια αξιολόγηση αποδοτικότητας εργοστασίων βιομηχανικού εξοπλισμού
title: Comparative multicriteria efficiency evaluation of industrial equipment plants
Creators: name: Παπαγρηγοριου Ιωαννα-Μαρια
Publisher: name: Technical University of Crete
Year: 2018

description: Το σύγχρονο επιχειρηματικό περιβάλλον χαρακτηρίζεται από έντονο ανταγωνισμό, ατέρμονες προσπάθειες για περιορισμό του χρόνου και του κόστους παραγωγής, την καλύτερη δυνατή αξιοποίηση των διαθέσιμων πόρων. Ένας βασικός παράγοντας που καθορίζει σε μεγάλο βαθμό την προσαρμογή και επιβίωση μιας εταιρίας στις εξελίξεις της αγοράς, είναι η παραγωγικότητα.

Βασικό αντικείμενο, της παρούσας εργασίας είναι η κατανόηση και ο ορισμός της πολυεπίπεδης έννοιας της παραγωγικότητας και η έρευνα και η εφαρμογή τρόπων μέτρησης της. Το πρόβλημα το οποίο μελετήθηκε αφορά 9 εργοστάσια βιομηχανικού εξοπλισμού ενός μεγάλου Ομίλου. Στα πλαίσια της εργασίας γίνεται βιβλιογραφική ανασκόπηση, καταγραφή και στη συνέχεια επιλογή και υπολογισμός περιορισμένου αριθμού κατάλληλων δεικτών παραγωγικότητας για τις επιμέρους μονάδες και για χρονικό διάστημα 2 ετών. Στη συνέχεια με χρήση της μεθόδου πολυκριτήριας ανάλυσης PROMETHEE γίνεται συγκριτική αξιολόγηση των εργοστασιακών μονάδων και προκύπτουν χρήσιμα συμπεράσματα. Η συμπεριφορά των αποτελεσμάτων της εφαρμογής της μεθοδολογίας μελετάται μέσα από εναλλακτικά σενάρια, συμπεριλαμβανομένης της εφαρμογής της μεθόδου Simos για τον καθορισμό των βαρών των επιμέρους κριτηρίων.
description: The modern business environment is characterized by intense competition, endless efforts to reduce time and cost of production and of the best possible exploitation of the available resources. Within this framework, productivity is a key factor which greatly determines a company's adjustment and survival to market developments.

The main object of the present dissertation is the understanding and definition of the multilevel concept of productivity as well as the research and the application of ways of measuring it. The problem under study refers to 9 industrial plants from a global group of companies. In the context of the study they have been carried out literature review, recording, selection and calculation of a limited number of appropriate productivity indicators of the individual units and for a period of 2 years. Then, the multi-criteria analysis PROMETHEE is applied in order to accomplish, a comparative assessment of the individual plant units ending up to the extraction of useful conclusions. The results arising are studied through the implementation of alternative scenarios, including the application of Simos individual criteria weight determination method.
Additional file 5 of Tools for measuring client experiences and satisfaction with healthcare in low- and middle-income countries: a systematic review of measurement properties
Creators: name: Banda, Susan
name: Nkungula, Nthanda
name: Chiumia, Isabel Kazanga
name: Rylance, Jamie
name: Limbani, Felix
Publisher: name: figshare
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 5. Terwee’s criteria quality assessment results.
VALIDAZIONE DELL�ALGORITMO DEL �PROGETTO CUORE� E ANALISI DI CONCORDANZA CON IL FRAMINGHAM RISK SCORE IN UNA COORTE A RISCHIO CARDIOVASCOLARE INTERMEDIO
Creators: name: PEREGO, FRANCESCA
Publisher: name: Universit� degli Studi di Milano
Year: 2014

description: Cardiovascular disease (CVD) is the leading cause of death in the world. In 2000 it caused more than 4.35 million deaths in Europe; Italy is no exception, with 42% overall CVD mortality. More than 50% of patients with coronary heart disease (CHD) have not been classified as at high risk. It is therefore important to correctly identify patients that need to be correctly stratified and to understand the better way to do it. Different risk score systems are available. The objective of this study is to analize how a scoring system is developed, validated and evaluated for impact into clinical practice and to compare different scoring systems.
IMPORTANCE OF DNA SEQUENCE DEISGN FOR HOMO- POLYMERIZABLE, SECONDARY STRUCTURES
Creators: name: Paluzzi, Victoria Elizabeth
Publisher: name: Purdue University Graduate School
Year: 2023
Subjects: classificationCode: 340199
subject: Analytical chemistry not elsewhere classified
classificationCode: 340302
subject: Macromolecular materials
classificationCode: 340303
subject: Nanochemistry
classificationCode: 340307
subject: Structure and dynamics of materials

description: DNA sequence design requires the ability to identify possible tertiary structural defects, secondary structure disruptions, and self-complimentary stretches that will disallow your complimentary strands to come together to form the desired duplex design. However, there is a need for those self-complimentary stretches, especially when designed with the intent for this to homo-oligomerize into the desired building block. With the programmability of nucleic acid hybridization, there is an expanding field wherein this specific, self-complimentary design feature can give new possibility of fine-tuning DNA self-assembly (Chapter 1) or overcome a previously thought limit of DNA ligation (Chapter 2).The first chapter will closely look at the branched kissing loop interaction. This interaction was studied as a homo-polymerizable DNA building block that is topologically closed. As such, this paranemic motif has increased stability due to the Watson-Crick base pairing being “protected” by a 3-base adenine branch which close the loop of the sticky-end, meaning no free ends in the binding region. With this, herein we report that the intended higher-level structure could influence the lower-level building block formation. In DNA nanotechnology, this could mean the final higher-level structure would allow for fine-tuning as this would dictate the building blocks that fill in the defected parts of the higher-level structure.The second chapter looks at the more finite than broad picture. Whilst the first chapter focusses on the impact the microscale has on the nanoscale through a homo-polymerizable design, the second chapter focusses on the ability to break barriers with homo-polymerizable design. In this chapter, we prove that with our splint strand design, when improved with a hairpin loop on the terminal ends, we can ligate DNA strands enzymatically as short as 16 nucleotides with an efficiency of 97% at high concentrations (100 uM). These hairpins allow for a stable, robust splint strand as they are a self-complimentary region which will maintain its shape throughout the process of joining together the 5’ and 3’ ends of the target strand.Overall, this dissertation hopes to prove that homo-polymerizable DNA sequence designs are helping expand upon the DNA nanotechnology toolbox by introducing new possibilities for nanoscale design, as well as push past previously held boundaries through necessary added stability afforded by the self-complimentary strands.
Nonparametric ridge estimation
Creators: name: Genovese, Christopher R.
name: Perone-Pacifico, Marco
name: Verdinelli, Isabella
name: Wasserman, Larry
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistics Theory (math.ST)
subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: We study the problem of estimating the ridges of a density function. Ridge estimation is an extension of mode finding and is useful for understanding the structure of a density. It can also be used to find hidden structure in point cloud data. We show that, under mild regularity conditions, the ridges of the kernel density estimator consistently estimate the ridges of the true density. When the data are noisy measurements of a manifold, we show that the ridges are close and topologically similar to the hidden manifold. To find the estimated ridges in practice, we adapt the modified mean-shift algorithm proposed by Ozertem and Erdogmus [J. Mach. Learn. Res. 12 (2011) 1249-1286]. Some numerical experiments verify that the algorithm is accurate.
description: Published in at http://dx.doi.org/10.1214/14-AOS1218 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Additional file 1 of The national atlas of tsetse flies and African animal trypanosomosis in Ethiopia
Creators: name: Gebre, Tsegaye
name: Kapitano, Berisha
name: Beyene, Dagnachew
name: Alemu, Dereje
name: Beshir, Ahimedin
name: Worku, Zelalem
name: Kifle, Teshome
name: Selamu, Ayana
name: Debas, Endalew
name: Kalsa, Aschenaki
name: Asfaw, Netsanet
name: Zhao, Weining
name: Paone, Massimo
name: Cecchi, Giuliano
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 1: S1. Apparent density of tsetse flies in Ethiopia by zone. Data collection period: 2010–2019.
Mobidrive: A six week travel diary
Creators: name: Chalasani, V. Saikumar
name: Axhausen, Kay W.
Publisher: name: ETH Zurich
Year: 2004
Subjects: Mobidrive
Survey design
Travel behaviour diary
List of variables
6 weeks
ETH Zürich
Institut für Verkehrsplanung und Transportsysteme

description: Travel Survey Metadata Series, 2
DEP Bulletin:Volume 35 Issue 13
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2011

description: The DEP bulletin is a semi-monthly publication of the New Jersey Department of Environmental Protection. It contains a list of construction permit applications recently filed or acted upon by the Department along with a calendar of events of interest, a schedule of public hearings, and Environmental Impact Statements acted upon during the period.
title: Πληροφορικό σύστημα προγραμματισμού χρόνου/κόστους σε προβλήματα φόρτωσης-εκφόρτωσης (Laytime Calculation)
Creators: name: Πάντζου Ζωή
Publisher: name: Technical University of Crete
Year: 1993

description: Μη διαθέσιμο
Detection of a large sample of Gamma Dor stars from Kepler space photometry and high-resolution ground-based spectroscopy
Creators: name: Tkachenko, A.
name: Aerts, C.
name: Yakushechkin, A.
name: Debosscher, J.
name: Degroote, P.
name: Bloemen, S.
name: Papics, P. I.
name: de Vries, B. L.
name: Lombaert, R.
name: Hrudkova, M.
name: Fremat, Y.
name: Raskin, G.
name: Van Winckel, H.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The space-missions MOST, CoRoT, and Kepler deliver a huge amount of high-quality photometric data suitable to study numerous pulsating stars. Our ultimate goal is a detection and analysis of an extended sample of Gamma Dor-type pulsating stars with the aim to search for observational evidence of non-uniform period spacings and rotational splittings of gravity modes in main-sequence stars typically twice as massive as the Sun. We applied an automated supervised photometric classification method to select a sample of 69 Gamma Doradus candidate stars. We used an advanced method to extract the Kepler light curves from the pixel data information using custom masks. For 36 of the stars, we obtained high-resolution spectroscopy with the HERMES spectrograph installed at the Mercator telescope. We find that all stars for which spectroscopic estimates of Teff and logg are available fall into the region of the HR diagram where the Gamma Dor and Delta Sct instability strips overlap. The stars cluster in a 700 K window in effective temperature, logg measurements suggest luminosity class IV-V. From the Kepler photometry, we identify 45 Gamma Dor-type pulsators, 14 Gamma Dor/Delta Sct hybrids, and 10 stars which are classified as "possibly Gamma Dor/Delta Sct hybrid pulsators". The results of photometric and spectroscopic classifications according to the type of variability are in perfect agreement. We find a clear correlation between the spectroscopically derived vsini and the frequencies of independent pulsation modes and show that it has nothing to do with rotational modulation of the stars but is related to their stellar pulsations. Our sample and frequency determinations offer a good starting point for seismic modelling of slow to moderately rotating Gamma Dor stars.
description: 12 pages, 9 figures. Accepted for publication in A&A
title: Έμπειρο σύστημα ελαχιστοποίησης φυράς μεταλλικών κατασκευών, τεχνητή νοημοσύνη και έμπειρα συστήματα, λογικός προγραμματισμός με περιορισμούς, Prolog III, εφαρμογές
Creators: name: Σιλβέστρος Τιμόθεος
Publisher: name: Technical University of Crete
Year: 1992

description: Μη διαθέσιμο
Local Thermal Equilibrium and KMS states in Curved Spacetime
Creators: name: Solveen, Christoph
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 81T20, 81T28, 82C99

description: On the example of a free massless and conformally coupled scalar field, it is argued that in quantum field theory in curved spacetimes with time-like Killing field, the corresponding KMS states (generalized Gibbs ensembles) at parameter β>0 need not possess a definite temperature in the sense of the zeroth law. In fact, these states, although passive in the sense of the second law, are not always in local thermal equilibrium (LTE). A criterion characterizing LTE states with sharp local temperature is discussed. Moreover, a proposal is made for fixing the renormalization freedom of composite fields which serve as "thermal observables" and a new definition of the thermal energy of LTE states is introduced. Based on these results a general relation between the local temperature and the parameter β is established for KMS states in (Anti) de Sitter spacetime.
description: 13 pages; to appear in Class. Quant. Grav
title: Essays on Aggregate Productivity and the Collateral Constraint
Creators: name: Mulay, Anup
Publisher: name: University of Kent
Year: 2021

description: We attempt to draw a straight line connecting financial shocks, portfolio reallocation by firms, and drop in aggregate productivity using a dynamic general equilibrium model. Our objective is to study whether the presence of financial frictions can produce business cycle-like response of variables to a financial shocks, as well as lower aggregate productivity. We propose a model that shows how an adverse shock to credit access for firms causes them to change the balance sheet portfolio composition of productive assets, which in turn causes loss of efficiency, and manifests as an efficiency wedge. We find some evidence for these dynamics in the data in the form of loss of measured TFP in countries after a financial shock, and a change in portfolio composition of assets for the U.S. data. Specifically, we find that post the 2008 crisis firms changed their allocation between assets of varying depreciation rates. We calibrate the model such that the impulse response functions are qualitatively similar to data facts. We take the canonical real business cycle model as base and modify it to incorporate our hypothesis stated above. We develop the simple model without frictions first and discuss its unique features, then add the friction and discuss how the full model responds to shocks and how the response of variables is very close to a business cycle. Then we address some technical issues in the model to make it comparable to a standard model with financial frictions. We also conduct welfare analysis and compute welfare costs by comparing a model of constrained firms with one of unconstrained firms.
Two-sample Behrens–Fisher problems for high-dimensional data: a normal reference scale-invariant test
Creators: name: Zhang, Liang
name: Zhu, Tianming
name: Zhang, Jin-Ting
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Evolutionary Biology
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: For high-dimensional two-sample Behrens–Fisher problems, several non-scale-invariant and scale-invariant tests have been proposed. Most of them impose strong assumptions on the underlying group covariance matrices so that their test statistics are asymptotically normal. However, in practice, these assumptions may not be satisfied or hardly be checked so that these tests may not be able to maintain the nominal size well in practice. To overcome this difficulty, in this paper, a normal reference scale-invariant test is proposed and studied. It works well by neither imposing strong assumptions on the underlying group covariance matrices nor assuming their equality. It is shown that under some regularity conditions and the null hypothesis, the proposed test and a chi-square-type mixture have the same normal and non-normal limiting distributions. It is then justifiable to approximate the null distribution of the proposed test using that of the chi-square-type mixture. The distribution of the chi-square type mixture can be well approximated by the Welch–Satterthwaite chi-square-approximation with the approximation parameter consistently estimated from the data. The asymptotic power of the proposed test is established. Numerical results demonstrate that the proposed test has much better size control and power than several well-known non-scale-invariant and scale-invariant tests.
NOTCH SIGNALING REGULATES STEMNESS AND METABOLISM OF LIPOSARCOMA CELLS
Creators: name: Tien, Pei Chieh
Publisher: name: Purdue University Graduate School
Year: 2022
Subjects: Cell metabolism
Cell development, proliferation and death

description: Liposarcoma (LPS) arises from adipocytes and is a rare malignancy among all cancer types, but represents the most common form of soft tissue sarcoma, with approximately 2,000 new cases reported annually. Clinically, liposarcomas are classified into four subtypes based on histological analysis: well-differentiated liposarcoma (WDLPS), dedifferentiated liposarcoma (DDLPS), myxoid/round cell liposarcoma, and pleomorphic liposarcoma. Although histological analysis provides useful information for identifying various liposarcoma subtypes, treatment options rely on a fundamental understanding of driver mutations and molecular mechanisms underlying tumorigenesis. This thesis focuses on elucidating important driver mutations and therapeutic targets to eradicate DDLPS. Notch signaling is an evolutionarily conserved signaling pathway essential for organ development and stem cell function. Aberrant Notch signaling underlies the tumorigenesis of many cancers including LPS. However, the specific role of Notch signaling in development of LPS remains elusive. In Chapter 2, I provide evidence demonstrating that Notch signaling plays a key role in cancer stem cells (CSCs), also referred to as tumor-initiating cells (TICs), that drive aggressive DDLPS. I used serial transplantation to enrich and generate a murine DDLPS cell line with constitutively activated Notch signaling (NICDOE). My analyses revealed that NICDOE DDLPS cells are heterogeneous and contain TICs that express cancer stem cell markers. Chapter 3 elucidates how Notch signaling regulates CSCs of LPS. I analyzed human LPS samples to establish a strong correlation between Notch signaling activation and tumor marker expression and prognosis. I further performed gene expression and metabolic analyses of NICDOE DDLPS cells. These assays revealed that NICDOE reduced mitochondrial respiration in DDLPS cells, which was associated with diminished expression of peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), a master regulator of mitochondrial biogenesis. CRISPR/CAS9-mediated deletion of the NICDOE cassette rescued the expression of PGC-1α and mitochondrial respiration in DDLPS cells. Similarly, overexpression of PGC-1α was sufficient to rescue mitochondrial biogenesis in DDLPS cells. Together, these data demonstrate that Notch signaling regulates CSCs, at least partially by controlling PGC-1α mediated mitochondria biogenesis.
Non-asymptotic fractional order differentiators via an algebraic parametric method
Creators: name: Liu, Dayan
name: Gibaru, Olivier
name: Perruquetti, Wilfrid
Publisher: name: arXiv
Year: 2012
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: Recently, Mboup, Join and Fliess [27], [28] introduced non-asymptotic integer order differentiators by using an algebraic parametric estimation method [7], [8]. In this paper, in order to obtain non-asymptotic fractional order differentiators we apply this algebraic parametric method to truncated expansions of fractional Taylor series based on the Jumarie's modified Riemann-Liouville derivative [14]. Exact and simple formulae for these differentiators are given where a sliding integration window of a noisy signal involving Jacobi polynomials is used without complex mathematical deduction. The efficiency and the stability with respect to corrupting noises of the proposed fractional order differentiators are shown in numerical simulations.
Systematic transcriptome wide analysis of lncRNA-miRNA interactions
Creators: name: Jalali, Saakshi
name: Bhartiya, Deeksha
name: Scaria, Vinod
Publisher: name: arXiv
Year: 2012
Subjects: subject: Genomics (q-bio.GN)
subject: Molecular Networks (q-bio.MN)
subject: FOS: Biological sciences

description: Long noncoding RNAs (lncRNAs) are a recently discovered class of non-protein coding RNAs which have now increasingly been shown to be involved in a wide variety of biological processes as regulatory molecules. Little is known regarding the regulatory interactions between noncoding RNA classes. Recent reports have suggested that lncRNAs could potentially interact with other noncoding RNAs including miroRNAs (miRNAs) and modulate their regulatory role through interactions. We hypothesized that long noncoding RNAs could participate as a layer of regulatory interactions with miRNAs. The availability of genome-scale datasets for argonaute targets across human transcriptome has prompted us to reconstruct a genome-scale network of interactions between miRNAs and lncRNAs. We used well characterized experimental Photoactivatable-Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation (PAR-CLIP) datasets and the recent genome-wide annotations for lncRNAs in public domain to construct a comprehensive transcriptome-wide map of miRNA regulatory elements. Comparative analysis revealed many of the miRNAs could target long noncoding RNAs, apart from the coding transcripts thus participating in a novel layer of regulatory interactions between noncoding RNA classes. We also find the miRNA regulatory elements have a positional preference, clustering towards the 3' and 5' ends of the long noncoding transcripts. We also further reconstruct a genome-wide map of miRNA interactions with lncRNAs as well as messenger RNAs. This analysis suggests widespread regulatory interactions between noncoding RNAs classes and suggests a novel functional role for lncRNAs. We also present the first transcriptome scale study on lncRNA-miRNA interactions and the first report of a genome-scale reconstruction of a noncoding RNA regulatory interactome involving lncRNAs.
Comparative Evaluation of IPT Resonant Circuit Topologies for Wireless Power Supplies of Implantable Mechanical Circulatory Support Systems
Creators: name: Knecht, Oliver
name: Kolar, Johann W.
Publisher: name: ETH Zurich
Year: 2017
Subjects: Inductive power transfer
Thermal modeling
Transcutaneous energy transfer

description: Proceedings of the 32nd Applied Power Electronics Conference and Exposition (APEC 2017)
description: ISBN:978-1-5090-5366-7
description: ISBN:978-1-5090-5367-4
Universal deformation rings of modules for algebras of dihedral type of polynomial growth
Creators: name: Bleher, Frauke M.
name: Talbott, Shannon N.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 16G10, 16G20

description: Let k be an algebraically closed field, and let Λ be an algebra of dihedral type of polynomial growth as classified by Erdmann and Skowroński. We describe all finitely generated Λ-modules V whose stable endomorphism rings are isomorphic to k and determine their universal deformation rings R(Λ,V). We prove that only three isomorphism types occur for R(Λ,V): k, k[[t]]/(t^2) and k[[t]].
description: 11 pages, 2 figures
Additional file 2 of The national atlas of tsetse flies and African animal trypanosomosis in Ethiopia
Creators: name: Gebre, Tsegaye
name: Kapitano, Berisha
name: Beyene, Dagnachew
name: Alemu, Dereje
name: Beshir, Ahimedin
name: Worku, Zelalem
name: Kifle, Teshome
name: Selamu, Ayana
name: Debas, Endalew
name: Kalsa, Aschenaki
name: Asfaw, Netsanet
name: Zhao, Weining
name: Paone, Massimo
name: Cecchi, Giuliano
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 2: S2. Apparent density of tsetse flies in Ethiopia by district (woreda). Data collection period: 2010–2019.
When can gravitational-wave observations distinguish between black holes and neutron stars?
Creators: name: Hannam, Mark
name: Brown, Duncan A.
name: Fairhurst, Stephen
name: Fryer, Chris L.
name: Harry, Ian W.
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Gravitational-wave observations of compact binaries have the potential to uncover the distribution of masses and angular momenta of black holes and neutron stars in the universe. The binary components' physical parameters can be inferred from their effect on the phasing of the gravitational-wave signal, but a partial degeneracy between the components' mass ratio and their angular momenta limits our ability to measure the individual component masses. At the typical signal amplitudes expected by the Advanced Laser Interferometer Gravitational-wave Observatory (signal-to-noise ratios between 10 and 20), we show that it will in many cases be difficult to distinguish whether the components are neutron stars or black holes. We identify when the masses of the binary components could be unambiguously measured outside the range of current observations: a system with a chirp mass $\mathcal{M} \le 0.871 $ M$_\odot$ would unambiguously contain the smallest-mass neutron star observed, and a system with $\mathcal{M} \ge 2.786 \Msun$ must contain a black hole. However, additional information would be needed to distinguish between a binary containing two 1.35 M$_\odot$ neutron stars and an exotic neutron-star--black-hole binary. We also identify those configurations that could be unambiguously identified as black-hole binaries, and show how the observation of an electromagnetic counterpart to a neutron-star--black-hole binary could be used to constrain the black-hole spin.
description: 5 pages, 4 figures. Final version to be published in Ap.J.Lett
Additional file 3 of The national atlas of tsetse flies and African animal trypanosomosis in Ethiopia
Creators: name: Gebre, Tsegaye
name: Kapitano, Berisha
name: Beyene, Dagnachew
name: Alemu, Dereje
name: Beshir, Ahimedin
name: Worku, Zelalem
name: Kifle, Teshome
name: Selamu, Ayana
name: Debas, Endalew
name: Kalsa, Aschenaki
name: Asfaw, Netsanet
name: Zhao, Weining
name: Paone, Massimo
name: Cecchi, Giuliano
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 3: S3. Presence and absence (surveyed but not detected) of tsetse fly species in Ethiopia. Data collection period: 2010–2019.
title: Μελέτη των συνθηκών εισαγωγής των επιχειρήσεων στο Χρηματιστήριο Αξιών Αθηνών κατά την περίοδο 1990-91
Creators: name: Ζαρίφης Παναγιώτης
Publisher: name: Technical University of Crete
Year: 1992

description: Μη διαθέσιμο
51V-NMR study of antiferromagnetic state and spin dynamics in the quasi-one-dimensional BaCo2V2O8
Creators: name: Ideta, Yukiichi
name: Kawasaki, Yu
name: Kishimoto, Yutaka
name: Ohno, Takashi
name: Michihiro, Yoshitaka
name: He, Zhangzhen
name: Ueda, Yutaka
name: Itoh, Mitsuru
Publisher: name: arXiv
Year: 2012
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report on our 51V-NMR study of static and dynamical magnetic properties in the quasi-one-dimensional antiferromagnet BaCo2V2O8. Although the NMR spectrum shows well-defined antiferromagnetic (AF) order in the Néel ground state, the AF characteristic from the NMR spectrum is incomplete between 3.5 K and TN= 5.4 K, which could be affected by quantum spin fluctuations. The AF NMR spectrum indicates two V sites experiencing different magnetic field magnitudes, HA1=2.1 kOe and HA2=3.8 kOe. These internal fields could be explained by accounting for the classical and the pseudo-dipolar fields from Co2+ spins with a proposed magnetic structure based on the neutron diffraction measurements. In the paramagnetic state, the nuclear spin relaxation is dominated by AF spin fluctuations through the dipolar-type coupling between V and surrounding Co2+ ions. The linear relation between the nuclear spin-lattice relaxation rate 1/T1T and the magnetic susceptibility chi indicates that the Q component of magnetic susceptibility chi(Q) is roughly proportional to chi, where Q is the AF wave number. A change in slope of 1/T1T with respect to χaround 150 K suggests a change in the AF spin fluctuation spectrum.
The crystal structure, XRD fitting and room temperature thermoelectric properties of Bi2Ln2O4Cu2Se2 from Synthesize, structure and physical properties of the new layered oxyselenides Bi2LnO4Cu2Se2 (Ln = rare earth)
Creators: name: Tan, Shugang
name: Gao, Chenhao
name: Wang, Cao
name: Jing, Qiang
name: Zhou, Tong
name: Yin, Guangchao
name: Sun, Meiling
name: Xing, Fei
name: Cao, Rui
name: Sun, Yuping
Publisher: name: The Royal Society
Year: 2020

description: We have synthesized a new series of layered oxyselenides Bi2LnO4Cu2Se2 (Ln = Nd, Sm, Eu, Dy, Er, Yb). Their crystal structures and physical properties were studied through X-ray diffraction, electric transport measurements, bulk magnetization and first-principle calculation. All these compounds have a tetragonal structure with space group I4/mmm. They exhibit hole-type metallic behaviours which is also verified by the DFT calculation. The new Bi2LnO4-type block in these compounds may give people some enlightenment in synthesizing new iron-based superconductors or other layered compounds
The convex distance inequality for dependent random variables, with applications to the stochastic travelling salesman and other problems
Creators: name: Paulin, Daniel
Publisher: name: arXiv
Year: 2012
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60E15, 82B44

description: We prove concentration inequalities for general functions of weakly dependent random variables satisfying the Dobrushin condition. In particular, we show Talagrand's convex distance inequality for this type of dependence. We apply our bounds to a version of the stochastic salesman problem, the Steiner tree problem, the total magnetisation of the Curie-Weiss model with external field, and exponential random graph models. Our proof uses the exchangeable pair method for proving concentration inequalities introduced by Chatterjee (2005). Another key ingredient of the proof is a subclass of $(a,b)$-self-bounding functions, introduced by Boucheron, Lugosi and Massart (2009).
description: 41 pages. Published in the Electronic Journal of Probability by the International Statistical Institute/Bernoulli Society, see http://ejp.ejpecp.org/article/view/3261
20 Ideas To Build Social Capital In The Data Science Ecosystem
Creators: name: Gray, Lawrence
Publisher: name: Zenodo
Year: 2022
Subjects: data science Social capital open science

description: We are all trying to establish ourselves and stand out in the ever-competitive Data Science ecosystem. What if we could do it in a way that benefits both us as individuals and the Data Science community? This talk will discuss a range of ideas for building confidence and brand for novice and experienced Data Enthusiasts. Simply attending a conference is a stepping stone for a beginner, whereas selecting to appear on a panel to discuss an open-source project could be an adventure for someone with more expertise. However, both pursuits put you on the correct path to achieving these goals. I will tell the story about my search for my place in the Data Science ecosystem, and I would like to assist you in finding yours. Building social capital doesn’t have to be a selfish endeavor. You should approach these opportunities with humility and honesty, and you should strive to build long-term, mutually beneficial relationships with the people you meet. Most importantly, be your most authentic self. We all want to be more connected to the Data Science community while advancing our careers and building experience. During this talk, we will discuss simple steps you can take to begin this fun journey, as well as more advanced avenues you can pursue. There are numerous activities you may participate in to build your social capital and help the community grow. We will talk about building your local LinkedIn Network, sitting on panels, volunteering on NumFocus committees, and 17 other ideas. Building social capital doesn’t have to be a selfish endeavor. You should approach these opportunities with humility and honesty, and you should strive to build long-term, mutually beneficial relationships with the people you meet. Most importantly, be your most authentic self. After this talk, I hope you’ll be inspired to go out into the world and grow our community.
Robustness of musculoskeletal simulation in strength training
Creators: name: Schellenberg, Florian
name: Lorenzetti, Silvio
Publisher: name: ETH Zurich
Year: 2015
Subjects: MODELLRECHNUNG/SPORT
BIOMECHANIK (BEWEGUNGSABLÄUFE IM SPORT)
KRAFTTRAINING + MUSKELTRAINING + BODY-BUILDING (SPORT)
STRENGHT TRAINING + MUSCLE TRAINING + BODY-BUILDING (SPORT)
MATHEMATICAL MODELING/SPORTS
BIOMECHANICS (COURSE OF MOVEMENTS IN SPORTS)
info:eu-repo/classification/ddc/796
info:eu-repo/classification/ddc/610
796
Medical sciences, medicine

description: Seventh Annual Congres of the Swiss Society of Sports Sciences, Lausanne, 12-‐13 February 2015 : Programme and Book of Abstracts
DEP Bulletin:Volume 35 Issue 14
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2011

description: The DEP bulletin is a semi-monthly publication of the New Jersey Department of Environmental Protection. It contains a list of construction permit applications recently filed or acted upon by the Department along with a calendar of events of interest, a schedule of public hearings, and Environmental Impact Statements acted upon during the period.
Additional file 4 of The national atlas of tsetse flies and African animal trypanosomosis in Ethiopia
Creators: name: Gebre, Tsegaye
name: Kapitano, Berisha
name: Beyene, Dagnachew
name: Alemu, Dereje
name: Beshir, Ahimedin
name: Worku, Zelalem
name: Kifle, Teshome
name: Selamu, Ayana
name: Debas, Endalew
name: Kalsa, Aschenaki
name: Asfaw, Netsanet
name: Zhao, Weining
name: Paone, Massimo
name: Cecchi, Giuliano
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 4: S4. Prevalence of bovine trypanosomosis in Ethiopia by zone. Data collection period: 2010–2019.