cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Linking Molecular Pathways and Large-Scale Computational Modeling to Assess Candidate Disease Mechanisms and Pharmacodynamics in Alzheimer's Disease
Creators: name: Stefanovski, Leon
name: Triebkorn, Paul
name: Spiegler, Andreas
name: Diaz-Cortes, Margarita-Arimatea
name: Solodkin, Ana
name: Jirsa, Viktor
name: McIntosh, Anthony Randal
name: Ritter, Petra
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: Alzheimer’s disease
subject: The Virtual Brain
subject: PET
subject: beta amyloid
subject: EEG
subject: MRI
subject: memantine
subject: personalized medicine
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Introduction: While the prevalence of neurodegenerative diseases associated with dementia such as Alzheimer's disease (AD) increases, our knowledge on the underlying mechanisms, outcome predictors, or therapeutic targets is limited. In this work, we demonstrate how computational multi-scale brain modeling links phenomena of different scales and therefore identifies potential disease mechanisms leading the way to improved diagnostics and treatment. Methods: The Virtual Brain (TVB; thevirtualbrain.org) neuroinformatics platform allows standardized large-scale structural connectivity-based simulations of whole brain dynamics. We provide proof of concept for a novel approach that quantitatively links the effects of altered molecular pathways onto neuronal population dynamics. As a novelty, we connect chemical compounds measured with positron emission tomography (PET) with neural function in TVB addressing the phenomenon of hyperexcitability in AD related to the protein amyloid beta (Abeta). We construct personalized virtual brains based on an averaged healthy connectome and individual PET derived distributions of Abeta in patients with mild cognitive impairment (MCI, N = 8) and Alzheimer's Disease (AD, N = 10) and in age-matched healthy controls (HC, N = 15) using data from ADNI-3 data base (http://adni.loni.usc.edu). In the personalized virtual brains, individual Abeta burden modulates regional Excitation-Inhibition balance, leading to local hyperexcitation with high Abeta loads. We analyze simulated regional neural activity and electroencephalograms (EEG). Results: Known empirical alterations of EEG in patients with AD compared to HCs were reproduced by simulations. The virtual AD group showed slower frequencies in simulated local field potentials and EEG compared to MCI and HC groups. The heterogeneity of the Abeta load is crucial for the virtual EEG slowing which is absent for control models with homogeneous Abeta distributions. Slowing phenomena primarily affect the network hubs, independent of the spatial distribution of Abeta. Modeling the N-methyl-D-aspartate (NMDA) receptor antagonism of memantine in local population models, reveals potential functional reversibility of the observed large-scale alterations (reflected by EEG slowing) in virtual AD brains. Discussion: We demonstrate how TVB enables the simulation of systems effects caused by pathogenetic molecular candidate mechanisms in human virtual brains.
Trade flows, unit prices and roundwood market integration in northern Europe
Creators: name: Viitanen, Jari
name: Toppinen, Anne
name: Magar, Surya Bahadur
name: Michie, Bruce
name: Nyrud, Anders Q.
name: Viitanen, Jari
name: Toppinen, Anne
name: Magar, Surya Bahadur
name: Michie, Bruce
name: Nyrud, Anders Q.
Publisher: name: Unknown
Year: 2006
Subjects: subject: International Development
subject: International Relations/Trade
subject: Marketing
subject: FOS: Economics and business
subject: Roundwood trade
subject: coniferous
subject: Northern Europe
subject: integration
subject: unit prices

description: Roundwood markets in Northern Europe have changed significantly due to the enlargement of EU in 1995 and 2004, and the formation of a common currency union between the 12 EU countries in 2001. However, wider research on the larger context of interaction between national markets in European Union is yet largely missing. This study shortly assesses roundwood market development and integration in Northern Europe. First, international roundwood and chips trade is studied by using simple descriptive analyses and annual national data from EFI’s and FAO’s databases for coniferous roundwood trade in 1980-2004. We classify countries as net importers or exporters of roundwood and examine how the trade flows have evolved over time. Second, we explore how the unit values of the roundwood and chips exports and imports have developed during 1980-2004, and explore signs for deepening integration of the roundwood markets in terms of convergence of unit prices and price variances. The results indicate that coniferous roundwood trade has been mainly moving from east (Russia, Baltic States) to west (Finland, Sweden, Norway), even though there has also been a small trading centre around Austria. The unit price development reveals that national export and import prices have clearly converged during the last decade.
Maximal Spectral Efficiency of OFDM with Index Modulation under Polynomial Space Complexity
Creators: name: Queiroz, Saulo
name: Silva, Wesley
name: Vilela, João P.
name: Monteiro, Edmundo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Signal Processing (eess.SP)
subject: Computational Complexity (cs.CC)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: In this letter, we demonstrate a mapper that enables all waveforms of OFDM with Index Modulation (OFDM-IM) while preserving polynomial time and space computational complexities. Enabling all OFDM-IM waveforms maximizes the spectral efficiency (SE) gain over the classic OFDM but, as far as we know, the computational overhead of the resulting mapper remains conjectured as prohibitive across the OFDM-IM literature. We show that the largest number of binomial coefficient calculations performed by the original OFDM-IM mapper is polynomial on the number of subcarriers, even under the setup that maximizes the SE gain over OFDM. Also, such coefficients match the entries of the so-called Pascal's triangle (PT). Thus, by assisting the OFDM-IM mapper with a PT table, we show that the maximum SE gain over OFDM can be achieved under polynomial (rather than exponential) time and space complexities.
description: Copyright (c) 2020 IEEE. Personal use is permitted. For any other purposes, permission must be obtained from the IEEE by emailing pubs-permissions@ieee.org
MOESM1 of BRInging the Diabetes prevention program to GEriatric populations (BRIDGE): a feasibility study
Creators: name: Beasley, Jeannette
name: Kirshner, Lindsey
name: Wylie-Rosett, Judith
name: Sevick, Mary
name: DeLuca, Laura
name: Chodosh, Joshua
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1. Diabetes Prevention Program Group Lifestyle Balanceâ„¢.
Carbon pricing through subsidy payment for thinning activities in Japan
Creators: name: Yoshimoto, Atsushi
name: Yoshimoto, Atsushi
Publisher: name: Unknown
Year: 2006
Subjects: subject: Environmental Economics and Policy
subject: International Development
subject: Carbon evaluation
subject: carbon pricing
subject: thinning subsidy
subject: dynamic programming
subject: calculus of variation

description: Carbon pricing was conducted through the subsidy payment for thinning activities in Japan within the optimization framework for the forest stand management. The optimal forest stand management model called DP-KYSS (dynamic programming model for Kyushu stand simulator) was utilized for the analysis of a sugi (Cryptomeria japonia) forest stand in the Kyushu region, Japan. The analyses showed that the thinning subsidy activated thinning activities with the reduction of carbon sequestered in a forest stand. Considering subsidies as a compensation for carbon loss by thinning, the evaluation of carbon showed that the present net value of cost per unit carbon loss became the highest for the rotation age of 35 years and the minimum for the rotation age of 50 to 65 years dependent upon the subsidy measure. At the rotation age of 100 years, the present net value of cost per unit carbon loss was found to be 44.56 to 110.13 Euro/Ct. The analyses showed that lengthening the period for subsidy would reduce the value of carbon. Subsidy pays more with more thinning reducing carbon sequestered in a forest stand.
Timber demand/supply analysis of east Asian timber trade - trade among eight Japanese regions, China, Korea
Creators: name: Yukutake, Kiyoshi
name: Yoshimoto, Atsushi
name: Yukutake, Kiyoshi
name: Yoshimoto, Atsushi
Publisher: name: Unknown
Year: 2006
Subjects: subject: International Development
subject: Marketing
subject: FOS: Economics and business
subject: Timber trade
subject: sustainable forest management
subject: domestic harvest
subject: price elasticity
subject: JAFSEM

description: Because of increasing supply of the imported wood at low price, the rate of wood selfsufficiency in Japan has dropped further below 20%. This resulted in abandoning the reforestation activities after harvesting, which could impinge on the sustainable forest management. In this study we first overview the current state of Japanese forestry with a focus on relationship between the timber market and the sustainable forest management. Secondly, we estimate price elasticity of lumber supply and demand for eight Japanese regions (Tohoku, Kanto, Hokuriku, Chubu, Kinki, Chugoku, Shikoku, and Kyushu), China and Korea. With the estimated price elasticities for these regions, we finally analyze the characteristics of the supply and demand structure through the spatial and inter-temporal partial equilibrium market model called JAFSEM (Japanese Forest Sector Model). Our results show the following; 1) at the present price level Japan would face to difficulty to continue the sustainable forest management, 2) Japanese regional lumber demand except Kyushu would increase, and 3) the additional demand for lumber would be met by Korea and China.
Final-State Phases in Doubly-Cabibbo-Suppressed Charmed Meson Nonleptonic Decays
Creators: name: Chiang, Cheng-Wei
name: Rosner, Jonathan L.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Cabibbo-favored nonleptonic charmed particle decays exhibit large final-state phase differences in $\bar K π$ and $\bar K^* π$ but not $\bar K ρ$ channels. It is of interest to know the corresponding pattern of final-state phases in doubly-Cabibbo-suppressed decays, governed by the $c \to d u \bar s$ subprocess. An experimental program is outlined for determining such phases via measurements of rates for $D \to K^* π$ and $K (ρ, ω,ϕ)$ channels, and determination of interference between bands in Dalitz plots. Such a program is feasible at planned high-intensity sources of charmed particles.
description: 12 pages, LaTeX, 2 figures, to be submitted to Phys. Rev. D. Revised version
Aceria beilschmiediae
Creators: name: Xue, Xiao-Feng
name: Zhang, Zhi-Qiang
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Eriophyidae
Aceria
Aceria beilschmiediae

description: Aceria beilschmiediae (Nalepa, 1921)
 Eriophyes beilschmiediae Nalepa, 1921: 148–149.
 Aceria beilschmiediae; Amrine & Stasny, 1994: 26.
 Host. Beilschmiedia roxburghiana (Lauraceae).
 Habit. Erineum.
 Distribution. Indonesia (Java).
 Remarks. Nalepa (1921) provided no figures for this species.
description: Published as part of Xue, Xiao-Feng & Zhang, Zhi-Qiang, 2009, 2257, pp. 1-128 in Zootaxa 2257 on page 33
Decoherence in resonantly driven bistable systems
Creators: name: Kohler, Sigmund
name: Hänggi, Peter
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study dissipative tunneling in a double well potential that is driven close to a resonance between the lowest tunnel doublet and a singlet. While the coherent dynamics can be described well within a three-level approximation, dissipative transitions to levels outside the singlet and the doublet may play a crucial role. Moreover, such transitions can enhance the entropy production significantly.
description: 12 pages, 7 figures, vch-book.cls
MOESM1 of Retrieval practice improves memory in patients with schizophrenia: new perspectives for cognitive remediation
Creators: name: Jantzi, Camille
name: Mengin, Amaury C.
name: Serfaty, David
name: Bacon, Elisabeth
name: Elowe, Julien
name: FranÃ§Ois Severac
name: Meyer, Nicolas
name: Berna, Fabrice
name: Vidailhet, Pierre
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Table S1. Estimation of the informative priors. Table S2. Percentage of words recalled across condition in the initial and final memory test in patients with schizophrenia and controls. Table S3. Results of the multivariate analyses. Table S4. Results of the multivariate analyses using frequentist statistical analyses (ANOVA). Table S5. Results of the sensitivity analyses using non-informative and pessimistic priors.
Creative Learning in Vida AB: A Case to describe organizational learning as a function of management style
Creators: name: Österberg, Peter
name: Österberg, Peter
Publisher: name: Unknown
Year: 2006
Subjects: subject: Agribusiness
subject: Management style
subject: climate
subject: super ordinate goals
subject: organizational performance

description: Research in general suggests management style to be an important determinant for organizational adaptability in order to learn how to cope with new situations; this is important when major environmental changes encounters an organization, as the organization need to keep pace in order to staying competitive on the market. Other research suggests that this kind learning take place in an implicit communications process. It is also suggests clear and challenging super ordinate goal setting to be a strong determinant to explain individual and organizational commitment and performance in general, and to mediate organizational creativity to be market-based. During the weekend of 8-9 January 2005, a storm, Gudrun, hit south of Sweden with hurricane-force. The impact of the storm was devastating across society as it destroyed large areas of forest. According to the Swedish National Board of Forestry, 75 million cubic meters was destroyed or damages. In this situation, the C.E.O. of Vida AB decides to buy 1 million cubic meters of the trees that had fallen due to the impact of Gudrun. In reality C.E.O. committed himself to buy 3.5 million cubic meters of fallen trees, and to take the cost for those parts that would proved to be damages. The decision made by the C.E.O. is obviously clear and challenging, suggesting it to make members of the organization to commit themselves to fulfill that decision. But how they learned, or develop, abilities to cope with this major change is unclear.
Argentine Beef Demand and Household Choices of Retail Channels
Creators: name: Rossini, Gustavo
name: Arancibia, Rodrigo García
name: Depetris Guiguet, Edith
name: Rossini, Gustavo
name: Arancibia, Rodrigo García
name: Depetris Guiguet, Edith
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Production Economics
subject: Beef
subject: Household Consumption
subject: Multinomial Logit
subject: Argentina

description: Household choices of outlet retail channels in beef purchases depend on several characteristics related to the quality of the product, convenience and ease of purchase, and economic factors such as price, income and payment methods. The aim of this paper is to study the influence of demographic and socio-economic attributes in the choice made by argentine consumers using a Multinominal Logit Model. The results show that the total number of purchases, the type of household, payment methods, and gender and schooling years of household head are the most relevant variables in the sample.
Stable and charge-switchable quantum batteries
Creators: name: Santos, Alan C.
name: Saguia, Andreia
name: Sarandy, Marcelo S.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A fully operational loss-free quantum battery requires an inherent control over the energy transfer process, with the ability of keeping the energy retained with no leakage. Moreover, it also requires a stable discharge mechanism, which entails that no energy revivals occur as the device starts its energy distribution. Here, we provide a scalable solution for both requirements. To this aim, we propose a general design for a quantum battery based on an {\it{energy current}} (EC) observable quantifying the energy transfer rate to a consumption hub. More specifically, we introduce an instantaneous EC operator describing the energy transfer process driven by an arbitrary interaction Hamiltonian. The EC observable is shown to be the root for two main applications: (i) a trapping energy mechanism based on a common eigenstate between the EC operator and the interaction Hamiltonian, in which the battery can indefinitely retain its energy even if it is coupled to the consumption hub; (ii) an asymptotically stable discharge mechanism, which is achieved through an adiabatic evolution eventually yielding vanishing EC. These two independent but complementary applications are illustrated in quantum spin chains, where the trapping energy control is realized through Bell pairwise entanglement and the stability arises as a general consequence of the adiabatic spin dynamics.
description: 8 pages and 3 figures
Chaos in temperature in the Sherrington-Kirkpatrick model
Creators: name: Rizzo, Tommaso
name: Crisanti, Andrea
Publisher: name: arXiv
Year: 2002
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We prove the existence of chaos in temperature in the Sherringhton-Kirkpatrick model. The effect is exceedingly small, namely of the ninth order in perturbation theory. The equations describing two systems at different temperatures constrained to have a fixed overlap are studied analytically and numerically, yielding information about the behaviour of the overlap distribution function $P_{T_1,T_2}(q)$ in finite-size systems.
description: REVTEX, 6 pages, 2 figures
Dirac Monopoles and Hawking radiation in Kottler spacetime
Creators: name: Bytsenko, A. A.
name: Goncharov, Yu. P.
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The natural extension of Schwarzschild metric to the case of nonzero cosmological constant $Λ$ known as the Kottler metric is considered and it is discussed under what circumstances the given metric could describe the Schwarzschild black hole immersed in a medium with nonzero energy density. Under the latter situation such an object might carry topologically inequivalent configurations of various fields. The given possibility is analysed for complex scalar field and it is shown that the mentioned configurations might be tied with natural presence of Dirac monopoles on black hole under consideration. In turn, this could markedly modify the Hawking radiation process.
description: 11 pages, LaTeX with using the ijmpa1.sty file from the package of World Scientific Publishing Co
MOESM2 of BRInging the Diabetes prevention program to GEriatric populations (BRIDGE): a feasibility study
Creators: name: Beasley, Jeannette
name: Kirshner, Lindsey
name: Wylie-Rosett, Judith
name: Sevick, Mary
name: DeLuca, Laura
name: Chodosh, Joshua
Publisher: name: figshare
Year: 2019
Subjects: subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Computational Biology

description: Additional file 2. CONSORT 2010 checklist of information to include when reporting a pilot or feasibility trial*.
Duality equivalence between nonlinear self-dual and topologically massive models
Creators: name: Ilha, Anderson
name: Wotzasek, Clovis
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this report we study the dual equivalence between the generalized self-dual (SD) and topologically massive (TM) models. To this end we linearize the model using an auxiliary field and apply a gauge embedding procedure to construct a gauge equivalent model. We clearly show that, under the above conditions, a nonlinear SD model always has a duality equivalent TM action.The general result obtained is then particularized for a number of examples, including the Born-Infeld-Chern-Simons (BICS) model recently discussed in the literature.
description: Dedicated to the memory of Prof. Juan Alberto Mignaco; To appear in Physics Letters B
Gauged Fermionic Q-balls
Creators: name: Levi, Thomas S.
name: Gleiser, Marcelo
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present a new model for a non-topological soliton (NTS) that contains interacting fermions, scalar particles and a gauge field. Using a variational approach, we estimate the energy of the localized configuration, showing that it can be the lowest energy state of the system for a wide range of parameters.
description: 5 pages, 2 figures; revised version to appear in Phys. Rev. D
Can fishing tourism improve sustainability of fishing chain?
Creators: name: Lai, Maria Bonaria
name: Lai, Maria Bonaria
Publisher: name: Unknown
Year: 2010
Subjects: subject: Environmental Economics and Policy
subject: Fishing tourism
subject: Sustainability
subject: Customer satisfaction

description: One environmental event verified during the last years in the Mediterranean sea is that the presence of tropical fishes is causing death of the original fauna. This has attracted the attention of not only the fishermen, but also that of the European Community and all of the associations (public and private) which work to preserve the environment. There are several initiatives to preserve the environment, and the “fermo biologico” is one of these. It tries to solve the Mediterranean fish’s depopulation problem, restricting the fishing in some period of the year. As known, the management of the biological resources is addressed to guarantee the environmental sustainability. This sustainability can be guaranteed by those who work in the fish sector, through new leisure activities, able to answer the increasing touristic demand. The objective of this study has been that to investigate whether leisure activity like fishing tourism can preserve the Mediterranean ecosystem and at the same time guarantee an additional income to the fishermen. This income could possibly balance for the obligation days stop, imposed them by the biological stop measure. The study has been conducted in the summer 2009 and has involved fishermen that practise fishing tourism in the Southern part of Sardinia.
Aceria cajani Channabasavanna 1966
Creators: name: Xue, Xiao-Feng
name: Zhang, Zhi-Qiang
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Eriophyidae
Aceria
Aceria cajani

description: Aceria cajani Channabasavanna, 1966
 Aceria cajani Channabasavanna, 1966: 62–63.
 Aceria cajani; Amrine & Stasny, 1994: 29–30.
 Aceria cajani; Kumar et al., 2001: 61.
 Host. Cajanus cajan (Fabaceae).
 Habit. Vagrant, discoloration, sterility, virus transmission.
 Distribution. Myanmar, India (Bangalore, Mysore), Nepal.
 Remarks. Aceria cajani is an important pest of pigeonpea and can transmit pigeonpea sterility mosaic virus (PPSMV) (Kumer et al. 2001, 2002 & 2005; Kulkarni et al. 2002).
description: Published as part of Xue, Xiao-Feng & Zhang, Zhi-Qiang, 2009, 2257, pp. 1-128 in Zootaxa 2257 on page 33
Local vs. Joint Measurements for the Entanglement of Assistance
Creators: name: Laustsen, T.
name: Verstraete, F.
name: van Enk, S. J.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We consider a variant of the entanglement of assistance, as independently introduced by D.P. DiVincenzo {\em et al.} ({\tt quant-ph/9803033}) and O. Cohen (Phys. Rev. Lett. {\bf 80}, 2493 (1998)). Instead of considering three-party states in which one of the parties, the assistant, performs a measurement such that the remaining two parties are left with on average as much entanglement as possible, we consider four-party states where two parties play the role of assistants. We answer several questions that arise naturally in this scenario, such as (i) how much more entanglement can be produced when the assistants are allowed to perform joint measurements, (ii) for what type of states are local measurements sufficient, (iii) is it necessary for the second assistant to know the measurement outcome of the first, and (iv) are projective measurements sufficient or are more general POVMs needed?
description: 20 pages, 6 figures, Minor changes, added reference to paper by O. Cohen
Aceria crotalariae
Creators: name: Xue, Xiao-Feng
name: Zhang, Zhi-Qiang
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Eriophyidae
Aceria
Aceria crotalariae

description: Aceria crotalariae (Nalepa, 1914)
 Eriophyes crotalariae Nalepa, 1914: 76–77.
 Aceria crotalariae; Amrine & Stasny, 1994: 38.
 Host. Crotalaria mucronata (Fabaceae).
 Habit. Erineum on leaves, twigs and flowers.
 Distribution. Indonesia (Java).
 Remarks. Nalepa (1914) provided no figures for this species.
description: Published as part of Xue, Xiao-Feng & Zhang, Zhi-Qiang, 2009, 2257, pp. 1-128 in Zootaxa 2257 on page 33
A switch in mechanism of action prevents doxorubicin-mediated cardiac damage
Creators: name: Cheong, Alison
name: Mcgrath, Sean
name: Robinson, Tina
name: Maliki, Ruqaya
name: Spurling, A
name: Lock, Peter
name: Rephaeli, A
name: Nudelman, A
name: Parker, Belinda
name: Pepe, S
name: Cutts, Suzanne
Publisher: name: La Trobe
Year: 2025
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3214
subject: Pharmacology and pharmaceutical sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 3211
subject: Oncology and carcinogenesis

description: Cancer patients treated with doxorubicin are at risk of congestive heart failure due to doxorubicin-mediated cardiotoxicity via topoisomerase IIβ poisoning. Acute cardiac muscle damage occurs in response to the very first dose of doxorubicin, however, cardioprotection has been reported after co-treatment of doxorubicin with acyloxyalkyl ester prodrugs. The aim of this study was to examine the role played by various forms of acute cardiac damage mediated by doxorubicin and determine a mechanism for the cardioprotective effect of formaldehyde-releasing prodrug AN-9 (pivaloyloxymethyl butyrate). Doxorubicin-induced cardiac damage in BALB/c mice bearing mammary tumours was established with a single dose of doxorubicin (4 or 16 mg/kg) administered alone or in combination with AN-9 (100 mg/kg). AN-9 protected the heart from doxorubicin-induced myocardial apoptosis and also significantly reduced dsDNA breaks, independent from the level of doxorubicin biodistribution to the heart. Covalent incorporation of [14C]doxorubicin into DNA showed that the combination treatment yielded significantly higher levels of formaldehyde-mediated doxorubicin-DNA adducts compared to doxorubicin alone, yet this form of damage was associated with cardioprotection from apoptosis. The cardiac transcriptomic analysis indicates that the combination treatment initiates inflammatory response signalling pathways. Doxorubicin and AN-9 combination treatments were cardioprotective, yet preserved doxorubicin-mediated anti-tumour proliferation and apoptosis in mammary tumours. This was associated with a switch in doxorubicin action from cardiac topoisomerase IIβ poisoning to covalent-DNA adduct formation. Co-administration of doxorubicin and formaldehyde-releasing prodrugs, such as AN-9, may be a promising cardioprotective therapy while maintaining doxorubicin activity in primary mammary tumours.
Sediment creep triggered by porous flow
Creators: name: Houssais, Morgane
name: Maldarelli, Charles
name: Morris, Jeffrey F.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Applied Physics (physics.app-ph)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: Quasi-2D experiments of a submerged sediment layer creeping downward were performed, varying the channel tilt and a porous flow under the respective thresholds for yielding. Logarithmic decay rates of the deformation are observed, with the rate increasing with both control parameters. A new dimensionless parameter, $P^*$, accounting for both mean porous flow and gravity force effects on particle motion, allows a collapse of all the deformation results on a single curve. Two distinct creep regimes are identified, and correspond to a systematic change of the void size distribution as $P^*$ increases.
Scope of Eco Tourism through Strategic Approach: A Review study of Rajasthan (India
Creators: name: Dr .Kuldeep Singh
Publisher: name: figshare
Year: 2021
Subjects: subject: 150603 Tourism Management
subject: FOS: Economics and business
subject: 150604 Tourism Marketing

description: Eco tourism is a new concept that supports the environmental conservation among local people, and also provides employment opportunities to them. Today, eco tourism is the emerging concept among tourists and encourages the development of tourism without degrading environment and natural resources. It has a potential to conserve and protect the natural areas and also known as vehicle to sustainable development. It is one of the accepted forms of alternative tourism that provides revenue to the people and also increases employment opportunities
Forecasting seasonality in prices of potatoes and onions: challenge between geostatistical models, neuro fuzzy approach and Winter method
Creators: name: Amiri, Arshia
name: Bakhshoodeh, Mohamad
name: Najafi, Bahaeddin
name: Amiri, Arshia
name: Bakhshoodeh, Mohamad
name: Najafi, Bahaeddin
Publisher: name: Unknown
Year: 2011
Subjects: subject: Crop Production/Industries
subject: Demand and Price Analysis
subject: Price
subject: Geostatistical model
subject: Kiriging
subject: Inverse distance weighting
subject: Winter’s method
subject: Adaptive neuro fuzzy inference system
subject: Potatoes
subject: Onions
subject: Iran

description: This paper, we studied the ability of geostatistical models (ordinary kriging (OK) and Inverse distance weighting (IDW)), adaptive neuro-fuzzy inference system (ANFIS) and Winter method for prediction of seasonality in prices of potatoes and onions in Iran over the seasonal period 1986_2001. Results show that the best estimators in order are winter method, ANFIS and geostatistical methods. The results indicate that Winter and ANFIS had powerful results for prediction the prices while geostatistical models were not useful in this respect.
description: Munich Personal RePEc Archive
Appendix II to: Crop Insurance Savings Accounts: A Viable Alternative to Crop Insurance?
Creators: name: Ramirez, Octavio A.
name: Ramirez, Octavio A.
Publisher: name: Unknown
Year: 2014
Subjects: Financial Economics

description: Given the procedures to be followed in this research, time series of price and yield realizations that are representative of what farmers might face in future years are needed to evaluate the feasibility of the proposed CISA. Reliable parametric estimates of future price and yield distributions are required to generate those realizations and sufficiently long historical price and yield time series are necessary in order to estimate those distributions. While long time series are available for most major commodity prices, multi-decade farm-level yield records are not as common. Fortunately, the University of Illinois Endowment Farms project has been collecting such records from 26 different “representative” corn producers during the last 50 years. Therefore, the “test-of-concept” analyses presented in this article are conducted for the specific case of corn producers in the State of Illinois.
description: Appendix II to article published in Applied Economic Perspectives and Policy
Aceria cryptomerus
Creators: name: Xue, Xiao-Feng
name: Zhang, Zhi-Qiang
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Eriophyidae
Aceria
Aceria cryptomerus

description: Aceria cryptomerus (Nalepa, 1918)
 Eriophyes cryptomerus Nalepa, 1918: 55–56.
 Aceria cryptomerus; Amrine & Stasny, 1994: 38.
 Host. Acalypha caturus (Euphorbiaceae).
 Habit. Erineum.
 Distribution. Indonesia (Java).
 Remarks. Nalepa (1918) provided no figures for this species.
description: Published as part of Xue, Xiao-Feng & Zhang, Zhi-Qiang, 2009, 2257, pp. 1-128 in Zootaxa 2257 on pages 33-34
Und dann?! Möglichkeiten der Sozialpädagogik bei der Begleitung von Übergängen im Arbeitsfeld Kinder- und Jugendpsychiatrie
Creators: name: Häusermann, Doris
name: Malfent, Sereina
Publisher: name: Zenodo
Year: 2019

description: In der vorliegenden Forschungsarbeit befassen sich die Autorinnen Doris Häusermann und Sereina Malfent mit dem Thema Übergänge in eine Anschlusslösung nach einem stationären Aufenthalt in der Kinder- und Jugendpsychiatrie. Sie stellen sich dabei die Frage, welchen Beitrag die Sozialpädagogik im Alltag der Kinder- und Jugendpsychiatrie leisten kann, damit solche Übergänge in Anschlusslösungen gelingen können. Die Ergebnisse einer qualitativen Forschung mittels Gruppeninterviews mit interdisziplinären Teams sowie Einzelinterviews mit sozialpädagogischen Fachpersonen zeigen auf, dass das Suchen und Finden von Anschlusslösungen für Patientinnen und Patienten der Kinder- und Jugendpsychiatrie herausfordernde Aufgaben sind. Der jeweilige individuelle Bedarf, das Lebensumfeld der Patientinnen und Patienten sowie auch gesellschaftliche Rahmenbedingungen wie geeignete Angebote und vorhandene Plätze spielen dabei eine Rolle. Ebenfalls konnte festgestellt werden, dass die Sozialpädagogik Potenzial birgt für die Gestaltung und Begleitung von Übergängen in Anschlusslösungen. Damit das Potenzial von Sozialpädagoginnen und Sozialpädagogen sowie anderen Fachpersonen der Kinder- und Jugendpsychiatrie vollständig ausgenutzt werden kann, braucht es eine klare Strukturierung der Austrittsprozesse sowie eine funktionierende interdisziplinäre Zusammenarbeit. Durch das Aufzeigen von Optimierungsmöglichkeiten für den Behandlungsalltag, einer sozialpädagogischen Sichtweise auf psychische Erkrankungen und die Diskussion von gesellschaftspolitischen Herausforderungen möchte die Arbeit einen konstruktiven Beitrag für das Arbeitsfeld der Kinder- und Jugendpsychiatrie leisten.
description: + Code Diss LU: hslusa basp be 2019 + Fussnote: Bachelorarbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Sozialpädagogik, 2019 + NL-Code: NLLUHSA201910
Monitoring the economy
Creators: name: Kernell, Georgia
name: Kernell, Samuel
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Neuroscience
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: This article argues that individuals should monitor the economy most during times of economic and political uncertainty or hardship. To test the argument, we investigate macrolevel factors that shape individuals’ attention to, and retention of, economic information in the U.S. Beyond economic indicators, including unemployment, inflation, and stock prices, we investigate political and electoral changes, international crises, and media coverage. In addition, we ask if individuals monitor the economy in fundamentally different (and politically consequential) ways, depending on their level of education. We test the hypotheses with over 80,000 survey respondents in the national, monthly Surveys of Consumers from 1979 to 2013. The findings reveal that respondents from all educational backgrounds respond in remarkably similar ways to changing national political and economic conditions. We conclude by discussing the findings’ implications for our conventional understanding of opinion formation.
Fluctuating Topological Defects in 2D Liquids: Heterogeneous Motion and Noise
Creators: name: Reichhardt, C.
name: Reichhardt, C. J. Olson
Publisher: name: arXiv
Year: 2002
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We measure the defect density as a function of time at different temperatures in simulations of a two dimensional system of interacting particles. Just above the solid to liquid transition temperature, the power spectrum of the defect fluctuations shows a 1/f signature, which crosses over to a white noise signature at higher temperatures. When 1/f noise is present, the 5-7 defects predominately form string like structures, and the particle trajectories show a 1D correlated motion that follows the defect strings. At higher temperatures this heterogeneous motion is lost. We demonstrate this heterogeneity both in systems interacting with a short ranged screened Coulomb interaction, as well as in systems with a long range logarithmic interaction between the particles.
description: 4 pages, 5 postscript figures
Zee-Burst: A New Probe of Neutrino Non-Standard Interactions at IceCube
Creators: name: Babu, K. S.
name: Dev, P. S. Bhupal
name: Jana, Sudip
name: Sui, Yicong
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We propose a new way to probe non-standard interactions (NSI) of neutrinos with matter using the ultra-high energy (UHE) neutrino data at current and future neutrino telescopes. We consider the Zee model of radiative neutrino mass generation as a prototype, which allows two charged scalars -- one $SU(2)_L$-doublet and one singlet, both being leptophilic, to be as light as 100 GeV, thereby inducing potentially observable NSI with electrons. We show that these light charged Zee-scalars could give rise to a Glashow-like resonance feature in the UHE neutrino event spectrum at the IceCube neutrino observatory and its high-energy upgrade IceCube-Gen2, which can probe a sizable fraction of the allowed NSI parameter space.
description: 7 pages, 2 figures; minor changes and added references, version to appear in Phys. Rev. Lett
MOESM1 of An overview of systematic reviews of complementary and alternative therapies for infantile colic
Creators: name: Perry, Rachel
name: Leach, Verity
name: Penfold, Chris
name: Davies, Philippa
Publisher: name: figshare
Year: 2019
Subjects: Space Science
Medicine
Pharmacology
Biotechnology
Science Policy
Computational Biology

description: Additional file 1. Description of included CAMs [51â€“53, 55]. Table S4: table of inclusion/exclusion criteria. Details of the search and data extraction [56]. Table S4 Excluded reviews. Table S6 Summary of the ROBIS domains. Table S7: Summary of systematic reviews of CAM treatments for infantile colic. Criteria for assessing confidence in AMSTAR-2.
Cubic Interactions of Bosonic Higher Spin Gauge Fields in $AdS_5$
Creators: name: Vasiliev, M. A.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The dynamics of totally symmetric free massless higher spin fields in $AdS_d$ is reformulated in terms of the compensator formalism for AdS gravity. The $AdS_5$ higher spin algebra is identified with the star product algebra with the $su(2,2)$ vector (i.e., $o(4,2)$ spinor) generating elements. Cubic interactions of the totally symmetric bosonic higher spin gauge fields in $AdS_5$, including the interaction with gravity, are formulated at the action level.
description: Latex, 67 pages; no figures, reference added, typos corrected; v3. Typo in Eq. (4.6) corrected; v4. More typos in coefficients corrected
Distribution of the Ratio of Consecutive Level Spacings for Different Symmetries and Degrees of Chaos
Creators: name: Corps, A. L.
name: Relaño, A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Theoretical expressions for the distribution of the ratio of consecutive level spacings for quantum systems with transiting dynamics remain unknown. We propose a family of one-parameter distributions $P(r)\equiv P(r;β)$, where $β\in[0,+\infty)$ is a generalized Dyson index, that describes the eigenlevel statistics of a quantum system characterized by different symmetries and degrees of chaos. We show that this crossover strongly depends on the specific properties of each model, and thus the reduction of such a family to a universal formula, albeit desirable, is not possible. We use the information entropy as a criterion to suggest particular ansatzs for different transitions, with a negligible associated error in the limits corresponding to standard random ensembles.
description: 11 pages, 9 figures, 3 tables. Accepted preprint; to appear in Phys. Rev. E
The Vision of the Absurd Aesthetic Machines, Entanglement and Affect
Creators: name: Georgeson, Michael
Publisher: name: University of East London
Year: 2019

description: The Vision of the Absurd is the culmination of five years research into how my fine art practice creates an affective encounter that can be more effectively and dynamically shared in the public realm. Central to this process was my early intuition that art has an excess that delivers understanding outside of conceptual cognition. Which is to say, art operates through material and aesthetic registers that need to be given space to reconnect audiences with the artist in shared experiences of discovery. The subsequent development of a series of aesthetic machines were all concerned with promoting these other modes of thought (Whitehead, 1968) and working with concepts that can become abstract material for expression (Zepke 2010). My initial sense that the non-linear causality of the absurd could move my art towards a more affective frequency was further shaped by my encounter with non-representational theory (Thrift, 2007) and put into practice in my role as the co-curator of Sensorium/Affect and Social media conferences at UEL between 2016-19. Furthermore, by experiencing artists who similarly placed digital moving images within a structure of haptic material vitality, such as Pipilotti Rist and Laure Prouvost, I found that the concept of the abstract machine (Zepke 2010) allowed my practice to radiate outwards as a kind of an aesthetic ontological experience (Debaise 2017). This ontological perspective becomes a significant means of exploring non-hierarchical smooth spaces (Deleuze and Guattari 2003) which activate a sense of my various creative capacities and form an absurd woven tapestry that celebrates creative abundance and destabilises the conceptual nature of interdisciplinary tactics.
Matching of the continuous gravitational wave in an all sky search
Creators: name: Sahay, S. K.
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We investigate the matching of continuous gravitational wave (CGW) signals in an all sky search with reference to Earth based laser interferometric detectors. We consider the source location as the parameters of the signal manifold and templates corresponding to different source locations. It has been found that the matching of signals from locations in the sky that differ in their co-latitude and longitude by $π$ radians decreases with source frequency. We have also made an analysis with the other parameters affecting the symmetries. We observe that it may not be relevant to take care of the symmetries in the sky locations for the search of CGW from the output of LIGO-I, GEO600 and TAMA detectors.
description: 16 pages, 7 figures, 3 Tables, To appear in Int. J. Mod. Phys. D
Axions as a probe of solar metals
Creators: name: Jaeckel, Joerg
name: Thormaehlen, Lennert J.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: If axions or axion-like particles exist and are detected, they will not only extend the standard model of particle physics but will also open a new way to probe their sources. Axion helioscopes aim to detect axions which are produced in the core of the sun. Their spectrum contains information about the solar interior and could in principle help to solve the conflict between high and low metallicity solar models. Using the planned International Axion Observatory (IAXO) as an example, we show that helioscopes could measure the strength of characteristic emission peaks caused by the presence of heavier elements with good precision. In order to determine unambiguously the elemental abundances from this information, an improved modelling of the states of atoms inside the solar plasma is required.
description: 6 pages, 3 figures, minor updates and corrections
Tau and Charm physics highlights
Creators: name: Roudeau, P.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In tau physics, we are at the frontier between the completion of the LEP program and the start of analyses from b-factories, which are expected to produce results in the coming years. Nice results from CLEO are steadily delivered in the meantime. For charm, impressive progress have been achieved by fixed target experiments in the search for CP violation and D^0 - \bar D^0 oscillations. First results from b-factories demonstrate the power of these facilities in such areas. The novel measurement of the D* width by CLEO happens to be rather different from current expectations. The absence of a charm factory explains the lack or the very slow progress in the absolute scale determinations for charm decays.
description: "Typos corrected and references added"