cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
N-Heterocyclische Olefine als neuartige Ligandensysteme und die Chemier arylsubstituierter Triphosphirane
Creators: name: Schumann, André
Publisher: name: Universität Rostock
Year: 2020
Subjects: subject: 540 Chemistry & allied sciences

description: Es zeigt sich, dass NHOs mit Rückgratprotonen in Gegenwart von Pd(0) isomerisieren und dieses als abnormales Carben koordinieren. Die erzwungene Koordination über die exocyclische Methylengruppe führt zu instabilen NHO-Komplexen. Pd(II)-NHO-Komplexe können als Präkatalysatoren für Buchwald-Hartwig-Kupplungen eingesetzt werden. Unter Verwendung von Tipp- und Dippsubstituenten können selektiv Triphosphirane synthetisiert werden. Um potentielle Phosphinidentransferreagenzien zu erhalten, werden ausgehend davon Titanocen-diphosphenkomplexe und NHC-Phosphinidenaddukte synthetisiert.
PopStar Evolutionary Synthesis Models II: Optical emission-line spectra from Giant H{\sc ii} regions
Creators: name: Martín-Manjón, M. L.
name: García-Vargas, M. L.
name: Mollá, M.
name: Díaz, A. I.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: This is the second paper of a series reporting the results from the PopStar evolutionary synthesis models. Here we present synthetic emission line spectra of H{\sc ii} regions photoionized by young star clusters, for seven values of cluster masses and for ages between 0.1 and 5.2 Myr. The ionizing Spectral Energy Distributions (SEDs) are those obtained by the PopStar code \citep*{mgb09} for six different metallicities, with a very low metallicity set, Z=0.0001, not included in previous similar works. We assume that the radius of the H{\sc ii} region is the distance at which the ionized gas is deposited by the action of the mechanical energy of the winds and supernovae from the central ionizing young cluster. In this way the ionization parameter is eliminated as free argument, since now its value is obtained from the cluster physical properties (mass, age and metallicity) and from the gaseous medium characteristics (density and abundances). We discuss our results and compare them with those from previous models and also with a large and data set of giant H{\sc ii} regions for which abundances have been derived in a homogeneous manner. The values of the [OIII] lines (at $λλ$ 4363, 4959, 5007Å) in the lowest metallicity nebulae are found to be very weak and similar to those coming from very high metallicity regions (solar or over-solar). Thus, the sole use of the oxygen lines is not enough to distinguish between very low and very high metallicity regions. In these cases we emphasize the need of the additional support of alternative metallicity tracers, like the [SIII] lines in the near-\textit{IR}.
description: 20 pages, 26 figures, accepted for publication in MNRAS Main Journal
Strong carrier-scattering in iron-pnictide superconductors with highest Tc obtained from charge transport experiments
Creators: name: Ishida, S.
name: Nakajima, M.
name: Tomioka, Y.
name: Ito, T.
name: Miyazawa, K.
name: Kito, H.
name: Lee, C. H.
name: Ishikado, M.
name: Shamoto, S.
name: Iyo, A.
name: Eisaki, H.
name: Kojima, K. M.
name: Uchida, S.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Characteristic normal-state charge transport is found in the oxygen-deficient iron-arsenides LnFeAsO1-y (Ln: La and Nd) with the highest Tc's among known Fe-based superconductors. The effect of "doping" in this system is mainly on the carrier scattering, quite distinct from that in high-Tc cuprates. In the superconducting regime of the La system with maximum Tc = 28 K, the low-temperature resistivity is dominated by a T^2 term. On the other hand, in the Nd system with Tc higher than 40 K, the carriers are subject to stronger scattering showing T-linear resistivity and small magnetoresistance. Such strong scattering appears crucial for high-Tc superconductivity in the iron-based system.
description: 7 pages, 6 figures
Magnetic-Field-Dependent Thermodynamic Properties of Square and Quadrupolar Artificial Spin Ice
Creators: name: Goryca, M.
name: Zhang, X.
name: Watts, J. D.
name: Nisoli, C.
name: Leighton, C.
name: Schiffer, P.
name: Crooker, S. A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Applied magnetic fields are an important tuning parameter for artificial spin ice (ASI) systems, as they can drive phase transitions between different magnetic ground states, or tune through regimes with high populations of emergent magnetic excitations (e.g., monopole-like quasiparticles). Here, using simulations supported by experiments, we investigate the thermodynamic properties and magnetic phases of square and quadrupolar ASI as a function of applied in-plane magnetic fields. Monte Carlo simulations are used to generate field-dependent maps of the magnetization, the magnetic specific heat, the thermodynamic magnetization fluctuations, and the magnetic order parameters, all under equilibrium conditions. These maps reveal the diversity of magnetic orderings and the phase transitions that occur in different regions of the phase diagrams of these ASIs, and are experimentally supported by magneto-optical measurements of the equilibrium "magnetization noise" in thermally-active ASIs.
description: 12 pages, 7 figures, in press at Physical Review B
Thermal breakage of a discrete one-dimensional string
Creators: name: Lee, Chiu Fan
Publisher: name: arXiv
Year: 2009
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We study the thermal breakage of a discrete one-dimensional string, with open and fixed ends, in the heavily damped regime. Basing our analysis on the multidimensional Kramers escape theory, we are able to make analytical predictions on the mean breakage rate, and on the breakage propensity with respect to the breakage location on the string. We then support our predictions with numerical simulations.
description: Mistakes in calculating Eq. (21) are now corrected
Evaluation of energy expenditure in athletes practising horseback riding
Creators: name: Vercesi, Luigi
name: Sampaolesi, Maurilio
name: Gemelli, Tiziano
name: Boratto, Renata
name: Tazzi, Antonio
name: Magnani, Bruno
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2010
Subjects: Energy expenditure; accelerometer; horse riding

description: Italian Journal of Anatomy and Embryology, Vol 115, No 1/2 (Supplement) 2010
Star formation histories of dwarf galaxies from the Colour-Magnitude diagrams of their resolved stellar populations
Creators: name: Cignoni, Michele
name: Tosi, Monica
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: In this tutorial paper we summarize how the star formation (SF) history of a galactic region can be derived from the colour-magnitude diagram (CMD) of its resolved stars. The procedures to build synthetic CMDs and to exploit them to derive the SF histories (SFHs) are described, as well as the corresponding uncertainties. The SFHs of resolved dwarf galaxies of all morphological types, obtained from the application of the synthetic CMD method, are reviewed and discussed. In short: 1) Only early-type galaxies show evidence of long interruptions in the SF activity; late-type dwarfs present rather continuous, or gasping, SF regimes; 2) A few early-type dwarfs have experienced only one episode of SF activity concentrated at the earliest epochs, whilst many others show extended or recurrent SF activity; 3) No galaxy experiencing now its first SF episode has been found yet; 4) No frequent evidence of strong SF bursts is found; 5) There is no significant difference in the SFH of dwarf irregulars and blue compact dwarfs, except for the current SF rates. Implications of these results on the galaxy formation scenarios are briefly discussed.
description: 29 pages. Tutorial Review to appear in the special issue "Dwarf-Galaxy Cosmology" in Advances in Astronomy
Imaging of protease functions – current guide to spotting cysteine cathepsins in classical and novel scenes of action in mammalian epithelial cells and tissues
Creators: name: Arampatzidou, Maria
name: Rehders, Maren
name: Dauth, Stephanie
name: Yu, Denise M.T.
name: Tedelind, Sofia
name: Brix, Klaudia
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: activity based probes; enzyme cytochemistry; green fluorescent protein; immunofluorescence; protein trafficking; endo-lysosomal proteases

description: The human genome encodes some hundreds of proteases. Many of these are well studied and understood with respect to their biochemistry, molecular mechanisms of proteolytic cleavage, expression patterns, molecular structure, substrate preferences and regulatory mechanisms, including their endogenous inhibitors. Moreover, precise determination of protease localisation within subcellular compartments, peri- and extracellular spaces has been extremely useful in elucidating biological functions of peptidases. This can be achieved by refined methodology as will be demonstrated herein for the cysteine cathepsins. Besides localisation, it is now feasible to study in situ enzymatic activity at the various levels of subcellular compartments, cells, tissues, and even whole organisms including mouse.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (2011)
Dark Energy and the Return of the Phoenix Universe
Creators: name: Lehners, Jean-Luc
name: Steinhardt, Paul J.
Publisher: name: arXiv
Year: 2008
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In cyclic universe models based on a single scalar field (e.g., the radion determining the distance between branes in M-theory), virtually the entire universe makes it through the ekpyrotic smoothing and flattening phase, bounces, and enters a new epoch of expansion and cooling. This stable evolution cannot occur, however, if scale-invariant curvature perturbations are produced by the entropic mechanism because it requires two scalar fields (e.g., the radion and the Calabi-Yau dilaton) evolving along an unstable classical trajectory. In fact, we show here that an overwhelming fraction of the universe fails to make it through the ekpyrotic phase; nevertheless, a sufficient volume survives and cycling continues forever provided the dark energy phase of the cycle lasts long enough, of order a trillion years. Two consequences are a new role for dark energy and a global structure of the universe radically different from that of eternal inflation.
description: 5 pages, 3 figures
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title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: ÐÐ¾Ð½Ð´Ð°ÑÐµÐ²Ð°, ÐÐ»ÐµÐ½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
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occupational safety and health
working conditions
facilities

description: Ð¦ÐµÐ»ÑÑ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð½Ð¾Ð¹ Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ¾Ð¹ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ð¸ Ð²ÑÑÑÑÐ¿Ð°ÐµÑ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐ¾ÑÑÐ¾ÑÐ½Ð¸Ñ ÑÐ°Ð±Ð¾ÑÐ¸Ñ Ð¼ÐµÑÑ Ð¸ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸ Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð½ÑÑ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ð¹ Ð¿Ð¾ Ð¾ÑÑÐ°Ð½Ðµ ÑÑÑÐ´Ð°, Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð½ÑÑ Ð½Ð° ÑÐ»ÑÑÑÐµÐ½Ð¸Ðµ ÑÑÐ»Ð¾Ð²Ð¸Ð¹ ÑÑÑÐ´Ð° ÑÐ°Ð±Ð¾ÑÐ½Ð¸ÐºÐ¾Ð² Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÐµÑÐ° OOO "Ð¢Ð¸ÑÐ°Ð½ ÐÐ½Ð¶Ð¸Ð½Ð¸ÑÐ¸Ð½Ð³".
description: The purpose of the master's thesis presented a comprehensive analysis of the state in favor of jobs and the development of economically sound labor protection measures aimed at improving working conditions for employees of the production plant OOO Â«Titanium Engineering".
Cliona lobata Hancock 1849
Creators: name: Pereira, Raquel
name: Larsson, Mats
name: Cárdenas, Paco
name: Thollesson, Mikael
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Porifera
Demospongiae
Clionaida
Clionaidae
Cliona
Cliona lobata

description: Cliona lobata Hancock, 1849
Cliona lobata Hancock 1849: 341–342, pl. XII fig. 4, 8.
Cliona lobata – Alander 1942: 80.
? Cliona howsei Hancock, 1849 – Levinsen 1893: 415 fig. 27.
Material examined (2 specimens)
SWEDEN • 1 spec.; 57.3042° N, 11.9321° E; 51– 49 m depth; 31 May 2007; Artprojektets Skagerrak-inventering leg. [KA68]; dredge; P082-111026-1; voucher: GNM Porifera 554 • 1 spec.; 58.1352° N, 11.2512° E; 51–49 m depth; 27 Aug. 2007; Artprojektets Skagerrak-inventering leg. [SK67]; dredge; P082-111026-2; voucher: GNM Porifera 555.
Description
The specimens had a boring morphology growing in shells, but papillae protruding from them. The colour in situ is unknown and light yellow when preserved in ethanol.
Skeleton
The skeleton is composed of megascleres, which are tylostyles measuring 230–350×7.5 µm (N=4), and spirasters as microscleres, which may be rare in some individuals, measuring 12.5–17.5µm (N=2) in length.
Ecology and distribution
The type locality is in the English Channel. However, there are reports from Denmark to South Africa, as well as from the Mediterranean and the Black Sea.
Remark
The species C. lobata differs from C. celata by several external morphological features, namely smaller and more abundant papillae, and thinner boring galleries. Additionally, C. lobata consistently possesses spirasters, while their presence in C. celata is only documented by Topsent (1900). However, given that C. celata is a species complex (Xavier et al., 2010) in dire need of taxonomic studies, and as spirasters can be rare in specimens of C. lobata, especially in massive morphotypes, it is possible that many specimens identified as C. celata in the past might actually belong to C. lobata.
description: Published as part of Pereira, Raquel, Larsson, Mats, Cárdenas, Paco & Thollesson, Mikael, 2025, Swedish marine demosponge fauna (Porifera: Demospongiae) sampled 80 years after Jägerskiöld's inventory, pp. 1-64 in European Journal of Taxonomy 983 on page 49, DOI: 10.5852/ejt.2025.983.2835, http://zenodo.org/record/15168665
Additional file 1 of The risk of acute and early HIV (AEH) infection among MSM with different behaviour trajectories: an open cohort study in Tianjin, China, 2011–2019
Creators: name: Wang, Xiaomeng
name: Zhang, Tiantian
name: Chang, Qinxue
name: Wang, Chun
name: Wang, Keyun
name: Yu, Zeyang
name: Zhang, Honglu
name: Huang, Huijie
name: Song, Desheng
name: Peixoto, Elissa
name: Yang, Jie
name: Li, Changping
name: Cui, Zhuang
name: Liu, Yuanyuan
name: Ma, Jun
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 1. Sexual risk behaviour score and fitting results of sexual risk behaviour trajectories. Table S1. Sexual risk behaviour score. Table S2. Five subgroups (3 3 3 3 3). Table S3. Five subgroups (3 1 3 1 1). Table S4. Four subgroups (3 3 3 3). Table S5. Four subgroups (1 1 1 3). Table S6. Three subgroups (3 3 3). Table S7. Three subgroups (3 1 2) (used in the main document)
Creating a square in the heart of the city : exploring the opportunities and challenges of creating a pedestrian plaza on 800-block Robson Street
Creators: name: O'Connor, Ryan
Publisher: name: The University of British Columbia
Year: 2014

description: London has Trafalgar Square, New York has Rockefeller Plaza, Rome has Piazza Navona. Around the world, public spaces help define a city and its residents. Often imbued with meaning and pride, these civic spaces provide room to breathe and to celebrate the city. Despite its internationally renowned standard of livability, Vancouver is sorely lacking in its inventory of urban public squares. With abundant greenspace and a pastoral setting, Vancouver’s public spaces emphasize an extroverted perspective. Rather than celebrating the city’s urbanity, Vancouver’s public realm provides outward views of the ocean, mountains, and natural elements that contribute to the city’s beauty.
Whole-plane self-avoiding walks and radial Schramm-Loewner evolution: a numerical study
Creators: name: Gherardi, Marco
Publisher: name: arXiv
Year: 2009
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We numerically test the correspondence between the scaling limit of self-avoiding walks (SAW) in the plane and Schramm-Loewner evolution (SLE) with k=8/3. We introduce a discrete-time process approximating SLE in the exterior of the unit disc and compare the distribution functions for an internal point in the SAW and a point at a fixed fractal variation on the SLE, finding good agreement. This provides numerical evidence in favor of a conjecture by Lawler, Schramm and Werner. The algorithm turns out to be an efficient way of computing the position of an internal point in the SAW.
description: 15 pages, 4 figures
Magneto-electric coupling in zigzag graphene nanoribbons
Creators: name: Jung, J.
name: Macdonald, A. H.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Zigzag graphene nanoribbons can have magnetic ground states with ferromagnetic, antiferromagnetic, or canted configurations, depending on carrier density. We show that an electric field directed across the ribbon alters the magnetic state, favoring antiferromagnetic configurations. This property can be used to prepare ribbons with a prescribed spin-orientation on a given edge.
description: 4 pages, 5 figures
Immunohistochemical and biochemical identification of MMP-2 in dentin
Creators: name: Papa, V.
name: Mazzoni, A.
name: Cova, A.
name: Angeloni, V.
name: Breschi, L.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: MMPs; dentin; FEI-SEM

description: Matrix metalloproteinases (MMPs) play an important role in many biological and pathological processes because of their ability to degrade all extracellular matrix (ECM) components. The purpose of this study was to identify MMP-2 in human dentin by immunohistochemical and biochemical methods. Dentin cryo-fractured fragments were obtained from human sound teeth, partially decalcified in 0.5 M EDTA pH 7.4 for 30min and submitted to a pre-embedding immunolabeling technique, using primary monoclonal antibodies anti-MMP-2 and exposed to a secondary antibody conjugated with gold nano-particles. Observations were performed by means of a FEI-SEM. Furthermore,the presence of MMP-2 was correlatively assayed by a colorimetric assay system (Quantisir) that allows direct measurement of MMP-2 levels. The immunohistochemical analysis revealed an intricate three-dimensional network of type I collagen and positive immunolabeling patterns for MMP-2 showing its distribution along with the collagen fibrils. The colorimetric assay resulted in higher presence of MMP-2 in mineralized dentin, compared to the partially demineralized counterpart. The role and function of dentin MMPs is not well known, but they have shown to contribute to auto-degenerative processes in dentin, such as inflammation of dental pulp, progression of caries lesions. This study demonstrated using an immunohistochemical and a biochemical approach that MMP-2 is an intrinsic component of the human dentin organic matrix, with possible roles in dentin matrix turnover and degenerative processes.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
From Kepler’s conjecture and fcc lattice to modelling of crowding in living matter
Creators: name: Del Monte, Ugo
name: Caiani, Enrico G.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: sphere packing; fcc lattice; void space; cell packing; extracellular matrix; interstitial space

description: Up to now, sphere packing has been investigated without any reference to living matter. This study focuses on the void space (VS) of sphere packing to mimic the extracellular spaces of living tissues. It was inspired by the importance of the extracellular matrix, the vehicle of micro and macromolecules involved in cell metabolism, intercellular communication and drug delivery. The analysis of sphere packing evidenced that in uniform random packing VS is about 1.9 times greater than in the face centered cubic (fcc) lattice (thus being very close to the 1.9 volume ratio of the cube to the sphere). This datum is a good reference for cell packing in vivo. The disproportionate increase of VS per sphere in loose packing in vitro is analyzed having in mind the variability in volume and composition of the interstitial spaces in vivo and cell trafficking. Arrangements of lymphocytes mimicking a two-dimensional hexagonal pattern and dense packing of disks generated by numerical procedures, are described in 7 μm-thick haematoxylin and eosin-stained histological slices from a human lymph node. In narrow tubes simulating roundish cells arranged in limited compartments of the interstice, sphere packing is characterized by noticeable increases of VS. The VS of this packing in vitro is compatible with variability in volume and composition of the interstitial spaces and with cell trafficking in vivo. This paper stresses that in mammalian tissues and organs cells can be packed quite more densely than spheres in the fcc lattice. As to pathology, attention is focused: (i) on overcrowding of cell organelles in some diseases, (ii) on shrinking or swelling of high amplitude, whose opposite effects are to concentrate or dilute intracellular structures and crowding of macromolecules, and (iii) on neoplastic tissues.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 1 (2013)
The History of the Solar System's Debris Disc: Observable Properties of the Kuiper Belt
Creators: name: Booth, Mark
name: Wyatt, Mark C.
name: Morbidelli, Alessandro
name: Moro-Martín, Amaya
name: Levison, Harold F.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The Nice model of Gomes et al. (2005) suggests that the migration of the giant planets caused a planetesimal clearing event which led to the Late Heavy Bombardment (LHB) at 880 Myr. Here we investigate the IR emission from the Kuiper belt during the history of the Solar System as described by the Nice model. We describe a method for easily converting the results of n-body planetesimal simulations into observational properties (assuming black-body grains and a single size distribution) and further modify this method to improve its realism (using realistic grain properties and a three-phase size distribution). We compare our results with observed debris discs and evaluate the plausibility of detecting an LHB-like process in extrasolar systems. Recent surveys have shown that 4% of stars exhibit 24 um excess and 16% exhibit 70 um excess. We show that the Solar System would have been amongst the brightest of these systems before the LHB at both 24 and 70 um. We find a significant increase in 24 um emission during the LHB, which rapidly drops off and becomes undetectable within 30 Myr, whereas the 70 um emission remains detectable until 360 Myr after the LHB. Comparison with the statistics of debris disc evolution shows that such depletion events must be rare occurring around less than 12% of Sun-like stars and with this level of incidence we would expect approximately 1 of the 413 Sun-like, field stars so far detected to have a 24 um excess to be currently going through an LHB. We also find that collisional processes are important in the Solar System before the LHB and that parameters for weak Kuiper belt objects are inconsistent with the Nice model interpretation of the LHB.
description: 16 pages, 13 figures, accepted for publication in MNRAS
title: ÐÐ°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ Ð»Ð¸Ð½Ð¸Ð¸ ÑÐ²ÑÐ·Ð¸ Ñ Ð´Ð²ÑÐ¼Ñ Ñ Ð°Ð¾ÑÐ¸ÑÐµÑÐºÐ¸Ð¼Ð¸ Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ°Ð¼Ð¸
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð Ð°ÑÑÐ¿ÐºÐ¸Ð½Ð°, ÐÐ»ÑÐ³Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾Ñ Ñ Ð°Ð¾ÑÐ°
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description: ÐÐ½Ð½Ð¾ÑÐ°ÑÐ¸Ñ: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð° ÑÐ¸ÑÑÐµÐ¼Ð° ÑÐºÑÑÑÐ¾Ð¹ Ð¿ÐµÑÐµÐ´Ð°ÑÐ¸ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¸ (Ð¡ÐÐ) Ñ Ð´Ð²ÑÐ¼Ñ Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ°Ð¼Ð¸ ÑÐ°Ð¾ÑÐ°. Ð¦ÐµÐ»ÑÑ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼ Ð¿ÐµÑÐµÐ´Ð°ÑÐ¸ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¸ Ñ Ð´Ð²ÑÐ¼Ñ Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ°Ð¼Ð¸ ÑÐ°Ð¾ÑÐ° Ñ Ð²ÑÐ±Ð¾ÑÐ¾Ð¼ Ð½Ð°Ð¸Ð»ÑÑÑÐµÐ¹. ÐÐ»Ñ ÑÑÐ¾Ð³Ð¾ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ð¾Ð±Ð·Ð¾Ñ Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ¾Ð² ÑÐ°Ð¾ÑÐ° Ñ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸ÐµÐ¼ Ð¸Ñ ÑÐ²Ð¾Ð¹ÑÑÐ²: Ð°ÑÑÑÐ°ÐºÑÐ¾Ñ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ, Ð¾ÑÐ¾Ð±ÑÐµ ÑÐ¾ÑÐºÐ¸, Ð»ÑÐ¿ÑÐ½Ð¾Ð²ÑÐºÐ¸Ðµ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸, ÑÐ½ÑÑÐ¾Ð¿Ð¸Ñ. Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÑÐµÐ¼Ñ Ð¿ÐµÑÐµÐ´Ð°ÑÐ¸ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¸ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ¾Ð² ÑÐ°Ð¾ÑÐ° Ñ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸ÐµÐ¼ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº ÑÑÐ¸Ñ ÑÐ¸ÑÑÐµÐ¼: ÑÑÐ¾Ð¹ÐºÐ¾ÑÑÑ Ðº Ð°ÑÐ°ÐºÐ°Ð¼, ÐºÐ°ÑÐµÑÑÐ²Ð¾ Ð¿ÐµÑÐµÐ´Ð°Ð²Ð°ÐµÐ¼Ð¾Ð³Ð¾ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ ÑÐ¸Ð³Ð½Ð°Ð»Ð°, ÑÐºÐ¾ÑÐ¾ÑÑÑ Ð¿ÐµÑÐµÑÑÑÐ¾Ð¹ÐºÐ¸, Ð¿Ð¾Ð»Ð¾ÑÐ° Ð¿ÑÐ¾Ð¿ÑÑÐºÐ°Ð½Ð¸Ñ. Ð ÑÐ°ÐºÐ¶Ðµ Ð²ÑÐ±ÑÐ°Ð½Ð° Ð½Ð°Ð¸Ð»ÑÑÑÐ°Ñ ÑÐ¸ÑÑÐµÐ¼Ð° Ð¿ÐµÑÐµÐ´Ð°ÑÐ¸ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¸ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ² Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð¸Ñ Ð¼Ð°ÑÑÐ¸ÑÑ Ð¿Ð°ÑÐ½ÑÑ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ð¹. ÐÐ°Ð»ÐµÐµ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð½Ð°Ð¸Ð»ÑÑÑÐµÐ¹ Ð¸Ð· ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð½ÑÑ ÑÐ¸ÑÑÐµÐ¼ Ð¿ÐµÑÐµÐ´Ð°ÑÐ¸ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¸ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÐ°Ð¾ÑÐ°.
title: Histories of Antibiotics: A One Health account of the arrival of antimicrobial drugs to Zimbabwe, Malawi and Uganda. Report for the Improving Human Health Flagship Initiative, Agriculture for Nutrition and Health research programme, CGIAR
Creators: name: Palanco Lopez, Paula
name: Chandler, Clare IR
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2020

description: The overall aim of this short project is to uncover some of the socio-historical roots of antibiotic use in both humans and non-humans outside of the European and American histories that are now well understood. We provide an historical account of the arrival and generalisation of use of antibiotics in three Eastern African countries: Zimbabwe, Malawi and Uganda. Drawing upon historical and ethnographic data, we describe when, how and in what context antibiotics arrived in these countries, providing an account of their early uses – both human and non-human. This project follows antibiotics as commodities, investigating how they were inserted within broader markets and the channels through which they were introduced in the African continent. The project pursues four distinct but interrelated objectives. First, to establish when and which antibiotics were first introduced in each country of focus. We find that this was not so different from Europe: the earliest mentions of antibiotics in Africa date from the mid-1940s, and refer to the same antibiotics that were being discovered and used in the rest of the world. Second, to investigate the context in which antibiotics arrived. We describe this as a set of already-functioning healthcare and veterinary systems, which were established by the colonial governments and missionary organisations throughout the first decades of the twentieth century. Third, to gain insight into the supply chains through which antibiotics were procured and distributed in each country. This was primarily through pharmaceutical companies from the UK and the US, which saw the market opportunities that drugs (and particularly antibiotics) offered in the colonised African territories. Finally, our fourth objective is to explore the actors behind the introduction of antibiotics, and the interests motivating them. We identify these as colonial governments, medical practitioners (private, colonial officers and missionaries) and pharmaceutical companies, who variously worked to ease the healthcare burden, and improve productivity and profit. Understanding the arrival and further spread of antibiotics in the focus countries can provide important insights about their current use. These findings show how antibiotics and biomedicine came to be associated together. Considering the interests that brought and kept antibiotics in African settings reveals how antibiotics have come to exist in the intersection between health, political agendas, economic interests, cultural identities and international relations. We intend this report to contribute to the development of initiatives to tackle AMR under a One Health framework, expanding the scope to include a diachronic perspective on the health of humans, animals and the environment.
HSP60 is muscle fiber-type specific and increases after endurance training: mice model
Creators: name: Barone, Rosario
name: Macaluso, Filippo
name: Sangiorgi, Claudia
name: D’Amico, Daniela
name: Dino, Elisa
name: Costa, Alessandra
name: Moresi, Viviana
name: Dario, Coletti
name: Adamo, Sergio
name: Farina, Felicia
name: Di Felice, Valentina
name: Zummo, Giovanni
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014

description: Heat shock protein (Hsp) 60 plays a key role in the translocation of proteins and cytoprotection, is primarily localized inside mitochondrial, and its levels increase in skeletal muscle upon exercise (Folkesson et al., 2013). The aim of this study was to examine muscle fiber specificity of HSP60 at rest and after an endurance training program of 45 days. Forth-eight male young (7-weeks old) healthy mice (BALB/c) were subdivided into six groups (8 mice per group). Three groups were trained on a rota-rod, at a gradually increasing duration and speed; while the other three groups did not perform any type of regular physical activity. One group of each condition was sacrificed after 15, 30 and 45 days. Forth-eight hours after the last exercise session all mice were sacrificed by cervical dislocation and posterior muscles group of hindlimb (gastrocnemius, soleus and plantaris) were dissected, weighed and embedded into paraffin or frozen in liquid nitrogen. Immunohystochemistry and immunofluorescence analysis showed that skeletal muscle type I fiber expressed high levels of Hsp60. The western blotting analyses of the entire posterior muscle group did not show any difference in the protein levels after endurance training, while the analysis of soleus muscle (reach in type I fibers) showed an over expression of Hsp60 after 30 and 45 days of endurance training. These data indicated that Hsp60 is muscle fibre type–specific. This may be due to the differences in mitochondrial content between slow and fast fibres. Anyway Hsp60 may be localized also in the cytoplasm, in the outer membrane, in the interstitium and in the blood stream, hence the role of this protein in endurance training need be elucidated.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
Recent advances in molecular diagnostics of colorectal cancer by genomic arrays: proposal for a procedural shift in biological sampling and pathological report
Creators: name: Castorina, Sergio
name: Barresi, Vincenza
name: Luca, Tonia
name: Privitera, Giovanna
name: Musso, Nicolò
name: Capizzi, Carmela
name: Condorelli, Daniele Filippo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2010
Subjects: colorectal cancer; genetic instability; genomic array

description: Two forms of genetic instability have been described in colorectal cancer: chromosomal instability, characterized by structural and numerical chromosomal abnormalities and associated to aneuploidy; and microsatellite instability, characterized by a deficiency in the mismatch repair system that leads to slippage in microsatellites and is associated to euploidy. Thirteen colorectal cancer sample DNAs were analyzed after colectomy. High-resolution genome-wide DNA copy number and Single Nucleotide Polimorphism genotyping analysis was performed by Affymetrix SNP 6.0 arrays that interrogates 906,600 single nucleotide polymorphisms and 945,826 copy number probes. We implemented this analysis as part of a routine procedure that includes the sampling of fresh tissue from the tumor mass without affecting the subsequent standard histopathological procedure. The novel molecular technology allows the determination of a genome-wide molecular karyotype using only 500 ng of high-quality tumor DNA; it distinguishes the two main types of genomic instability, discriminating between chromosomal instability positive and negative tumors. It also detects loss of heterozygosity (LOH) regions, called copy neutral-LOH. Tumor-associated copy neutral-LOH regions may play a pivotal role in oncogenesis when they determine duplications of either activating or loss of function gene mutation. We observed recurrent gains of chromosomes 2, 7, 8q, 9, 12, 13, 20 and losses of chromosomes 4, 5, 8p, 15, 17p, 18, 22, and Y, in agreement with previous cytogenetic studies. The use of such sampling procedure could stimulate the routine detection of point mutations in specific genes, thus avoiding subsequent sectioning of formalin-fixed and paraffin-embedded samples.
description: Italian Journal of Anatomy and Embryology, Vol 115, No 1/2 (2010)
Osteogenic differentiation of human dental pulp stem cells in 3D scaffolds
Creators: name: Riccio, Massimo
name: Resca, Elisa
name: Maraldi, Tullia
name: Migliaresi, Claudio
name: Motta, Antonella
name: Ferrari, Adriano
name: Bruzzesi, Giacomo
name: De Pol, Anto
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2010
Subjects: DPSC; Stem Cells; Osteogenic Differentiation; 3D Scaffold; Fibroin

description: Italian Journal of Anatomy and Embryology, Vol 115, No 1/2 (Supplement) 2010
title: ÐÐ¾Ð²ÑÑÐµÐ½Ð¸Ðµ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²ÑÐ¼Ð¸ ÑÐµÑÑÑÑÐ°Ð¼Ð¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ (Ð¿Ð¾ Ð·Ð°ÐºÐ°Ð·Ñ ÐÐÐ "ÐÐ²ÑÐ¾ÑÑÐ°Ð½Ñ")
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ¾Ð¿ÑÑÐ¾Ð²Ð°, ÐÐ»Ð¸Ð·Ð°Ð²ÐµÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²ÑÐµ ÑÐµÑÑÑÑÑ
Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸
ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ
financial resources
management

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÑÑÐ½Ð¾ÑÑÑ ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²ÑÑ ÑÐµÑÑÑÑÐ¾Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸, Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ Ð¸ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²ÑÐ¼Ð¸ ÑÐµÑÑÑÑÐ°Ð¼Ð¸. Ð¢Ð°ÐºÐ¶Ðµ Ð±ÑÐ» Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¸Ð¼ÑÑÐµÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿Ð¾Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ, Ð°Ð½Ð°Ð»Ð¸Ð· Ð»Ð¸ÐºÐ²Ð¸Ð´Ð½Ð¾ÑÑÐ¸ Ð¸ Ð¿Ð»Ð°ÑÐµÐ¶ÐµÑÐ¿Ð¾ÑÐ¾Ð±Ð½Ð¾ÑÑÐ¸, Ð°Ð½Ð°Ð»Ð¸Ð· Ð´ÐµÐ»Ð¾Ð²Ð¾Ð¹ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸, ÑÐ°ÐºÑÐ¾ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¿ÑÐ¸Ð±ÑÐ»Ð¸ Ð¾Ñ Ð¿ÑÐ¾Ð´Ð°Ð¶. ÐÑ Ð¿ÑÐ¾Ð²ÐµÐ»Ð¸ ÐÐÐ¡- Ð¸ XYZ-Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐºÐ»Ð°Ð´ÑÐºÐ¸Ñ Ð·Ð°Ð¿Ð°ÑÐ¾Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸, Ð¾Ð¿ÑÐµÐ´ÐµÐ»Ð¸Ð»Ð¸ ÑÐ¾Ð²Ð°ÑÐ½ÑÐµ Ð³ÑÑÐ¿Ð¿Ñ, ÐºÐ¾ÑÐ¾ÑÑÐµ Ð¿ÑÐ¸Ð½Ð¾ÑÑÑ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð½Ð°Ð¸Ð±Ð¾Ð»ÑÑÑÑ Ð¿ÑÐ¸Ð±ÑÐ»Ñ. Ð¢Ð°ÐºÐ¶Ðµ Ð±ÑÐ»Ð° Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ð° Ð¾ÑÐµÐ½ÐºÐ° Ð´ÐµÐ±Ð¸ÑÐ¾ÑÑÐºÐ¾Ð¹ Ð·Ð°Ð´Ð¾Ð»Ð¶ÐµÐ½Ð½Ð¾ÑÑÐ¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¸ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ ÐµÐµ ÑÐ¾ÐºÑÐ°ÑÐµÐ½Ð¸Ñ.
description: In bachelor work we consider the essence of the financial resources of the organization, the basic model and financial management indicators. Also it was presented the analysis of financial status, liquidity and solvency analysis, analysis of business activity organizations, factor analysis profits from sales. We spent ABC- and XYZ-analysis of the inventory organization, defined product groups that generate the most profit organization. It was also assessed receivables organization and offered recommendations for its reduction.
Suberites Nardo 1930
Creators: name: Pereira, Raquel
name: Larsson, Mats
name: Cárdenas, Paco
name: Thollesson, Mikael
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Porifera
Demospongiae
Suberitida
Suberitidae
Suberites

description: Genus Suberites Nardo, 1930
Remarks on the genus
The genus Suberites Nardo, 1930 is characterised by a confused skeleton constituted by (sub)tylostyles and/or microscleres that are microspined centrotylote oxeas, strongyles or even styles, with all of these microscleres possibly in the same specimen. The species of this genus do not have clear ectosomal differentiation. The habitus is thin encrusting to massive, has a compact consistency, velvety surface, and the colour is from beige to tawny. This description together with other similar descriptions of other genera within the family Suberitidae makes the assignment of a specimen to the correct genus difficult. For the genus itself, many of the species were described more than a century ago and many of the names have been synonymised (e.g., Burton 1953) or forgotten, and many of the species have a very short and cryptic description. There are currently 83 accepted species for the genus and about 102 unaccepted names. For the NEA there are currently 76 accepted species. Here, we present very preliminary names for the Suberites species, pending a thorough taxonomic revision.
description: Published as part of Pereira, Raquel, Larsson, Mats, Cárdenas, Paco & Thollesson, Mikael, 2025, Swedish marine demosponge fauna (Porifera: Demospongiae) sampled 80 years after Jägerskiöld's inventory, pp. 1-64 in European Journal of Taxonomy 983 on page 51, DOI: 10.5852/ejt.2025.983.2835, http://zenodo.org/record/15168665
Inhibitory and excitatory enteric neurons of the mouse duodenum co-express the Glucagon-like Peptide 1 or Glucagon-like Peptide 2 receptors
Creators: name: Vannucchi, Maria Giuliana
name: Cinci, Lorenzo
name: Faussone-Pellegrini, Maria Simonetta
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2010

description: Italian Journal of Anatomy and Embryology, Vol 115, No 1/2 (Supplement) 2010
Radiative pulsar magnetospheres: oblique rotators
Creators: name: Pétri, Jérôme
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Pulsar magnetospheres are filled with relativistic pairs copiously emitting photons detected from the radio wavelengths up to high and very high energies, in the GeV and sometimes in the TeV range. Efficient particle acceleration converts the stellar rotational kinetic energy into radio, X-ray and gamma-ray photons. Force-free magnetospheres, being dissipationless, cannot operate this conversion. Some non ideal plasma effects must set in within the magnetosphere. In this paper, we compute numerical solutions of pulsar radiative magnetospheres in the radiation reaction limit, where radiation fully balances single particle acceleration. Using an appropriate Ohm's law, the dissipation is only controlled by the pair multiplicity factor~$κ$. Moreover we allow for either a minimal radiative region where dissipation is added only where required or for a force-free inside radiative outside model. This approach naturally and self-consistently connects the particle dynamics to its radiation field in the ultra-relativistic regime. Our solutions tend to the force-free limit for moderately large multiplicities, $κ\gg 1$, decreasing the spin-down energy conversion into radiation. Nevertheless, for sufficiently low multiplicity $κ\lesssim1$, a significant fraction of the spin-down energy flows into radiation via particle acceleration. The work done by the electromagnetic field on the plasma mainly occurs in the current sheet of the striped wind, right outside the light-cylinder. Nevertheless the impact on the magnetic topology is negligible whatever the model. Therefore the associated sky maps and light-curves are only weakly impacted as shown.
description: Accepted for publication in Monthly Notices of the Royal Astronomical Society Main Journal
New Regularization in Extra Dimensional Model and Renormalization Group Flow of the Cosmological Constant
Creators: name: Ichinose, Shoichi
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Casimir energy is calculated for 5D scalar theory in the {\it warped} geometry. A new regularization, called {\it sphere lattice regularization}, is taken. The regularized configuration is {\it closed-string like}. We numerically evaluate $\La$(4D UV-cutoff), $\om$(5D bulk curvature, warp parameter) and $T$(extra space IR parameter) dependence of Casimir energy. 5D Casimir energy is {\it finitely} obtained after the {\it proper renormalization procedure.} The {\it warp parameter} $\om$ suffers from the {\it renormalization effect}. We examine the cosmological constant problem.
description: 7 pages, 2 figures, Proceedings of SCGT09
Breast cancer cells and fibroblasts in co-culture: reciprocal influences on cell adhesion, membrane fluidity and migration
Creators: name: Angelucci, Cristiana
name: Lama, Gina
name: Proietti, Gabriella
name: Fabbri, Cristina
name: Masetti, Riccardo
name: Sica, Gigliola
name: Maulucci, Giuseppe
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011

description: The growing role of the reciprocal interaction between epithelial and stromal cells in the development and progression of breast cancer has been recognized. In particular, the migratory/invasive behaviour of tumor cells seems to be strongly influenced by their dialogue with neighbouring stromal cells. To verify if this cross-talk may affect some molecular and functional aspects of the cell biology correlated with the metastasizing vocation of the tumor cells (i.e. adhesion molecule expression, membrane fluidity, migration), we co-cultured estrogen receptor (ER)-positive, poorly invasive and low metastasizing (MCF-7) or ER-negative, highly invasive and metastatic (MDA-MB-231) breast cancer cells with fibroblasts isolated from breast healthy skin (normal fibroblasts, NFs) or from breast tumor stroma (cancer associated fibroblasts, CAFs) in monolayer or in a three-dimensional system (nodules). We previously reported the ability of NFs and CAFs to respectively induce or inhibit the epithelial adhesion molecule, E-cadherin, expression in MCF-7 cells. In the present study, the expression of the mesenchymal adhesion protein N-cadherin (N-cad) was investigated by confocal immunofluorescence microscopy on frozen nodule sections. An increase in N-cad levels was observed in CAFs, but not in NFs, as a result of the interaction with both kinds of epithelial cancer cells. CAFs, in turn, promoted an increase in N-cad level of MDA-MB-231 cells and induced its expression in MCF-7 cells, originally negative for N-cad. Two-photon microscopy imaging of cells labeled with Laurdan, a membrane fluorescent probe, was used to investigate fluidity changes in plasma membranes of all the cell types in monolayer cultures. Tumor cell/fibroblast interaction enhanced fluidity of cancer cell membrane while tumor cells generally promoted an increase in fibroblast membrane packing density. Cell tracking by confocal microscopy demonstrated that the interaction of mammary cancer cells with NFs or CAFs determined a definite increment in tumor cell migration velocity, even with a marked enhancement of the migration directionality induced by CAFs. Our results demonstrate a reciprocal influence of mammary cancer and stromal cells on various adhesiveness/invasiveness features. In particular, an overall pro-tumoral/-invasive effect of CAFs on both well- and poorly differentiated mammary cancer cells was exteriorized by reduction of cell adhesion, induction of membrane fluidity, and migration velocity and directionality, along with a promotion of epithelial-mesenchymal transition.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
TapTree: Process-Tree Based Host Behavior Modeling and Threat Detection Framework via Sequential Pattern Mining
Creators: name: Mamun, Mohammad
name: Buffett, Scott
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Audit logs containing system level events are frequently used for behavior modeling as they can provide detailed insight into cyber-threat occurrences. However, mapping low-level system events in audit logs to highlevel behaviors has been a major challenge in identifying host contextual behavior for the purpose of detecting potential cyber threats. Relying on domain expert knowledge may limit its practical implementation. This paper presents TapTree, an automated process-tree based technique to extract host behavior by compiling system events' semantic information. After extracting behaviors as system generated process trees, TapTree integrates event semantics as a representation of behaviors. To further reduce pattern matching workloads for the analyst, TapTree aggregates semantically equivalent patterns and optimizes representative behaviors. In our evaluation against a recent benchmark audit log dataset (DARPA OpTC), TapTree employs tree pattern queries and sequential pattern mining techniques to deduce the semantics of connected system events, achieving high accuracy for behavior abstraction and then Advanced Persistent Threat (APT) attack detection. Moreover, we illustrate how to update the baseline model gradually online, allowing it to adapt to new log patterns over time.
description: 20pages