cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Hofstadters Schmetterling
Creators: name: Evers, Ferdinand
name: Richter, Klaus
Publisher: name: Blick in die Wissenschaft
Year: 2018

description: Der Pulitzer-Preisträger Douglas Hofstadter aus Bloomington, USA, ist einem breiteren Publikum vielleicht am ehesten bekannt durch sein Werk „Gödel, Escher, Bach: Ein endlos geflochtenes Band“ aus den achtziger Jahren. Das Buch ist, wie Hofstadter es einmal auf einen kurzen Nenner gebracht hat, „der sehr persönliche Versuch, zu erklären, wie beseelte Wesen aus unbeseelter Materie entstehen können“. Dieses Thema hat ihn sein Lebtag umgetrieben, bis hin zum heutigen Tag. Vielleicht weniger populär, aber unter Experten umso berühmter, ist eine frühe Entdeckung, die Hofstadter bereits 1974 in Regensburg gemacht hatte. Damals noch Doktorand, verbrachte er einen halbjährigen Gastaufenthalt an der Fakultät für Physik der hiesigen Universität: Ihm glückte in dieser Zeit die erstmalige Berechnung des Energiespektrums von Metall-Elektronen im Magnetfeld. In einer gewissen Darstellung ähnelt es einem Schmetterling, und so wurde das Spektrum als „Hofstadter-Butterfly“ bekannt. Hofstadters Doktorarbeit kann man in zweierlei Hinsicht paradigmatisch nennen: Sie stellt zum einen ein frühes Paradebeispiel dar für das enorme Potential, das computergestützte Methoden für die theoretische Physik haben können. Dieses Potential wurde jedoch zunächst nicht erkannt: Seine höchst innovative numerische Herangehensweise wurde anfangs von seinen Mentoren als „Numerologie“ abgetan, eine für Hofstadter sehr prägende Erfahrung (siehe Interview ab Seite xx). Zum anderen wurde mit dem „Butterfly-Spektrum“ wohl zum ersten Mal eine selbstähnliche Struktur, ein „Fraktal“, in der Quantenphysik gefunden. Fraktale sind bildhafte Muster, die die merkwürdige Eigenschaft aufweisen, dass sich ein Ausschnitt des Musters nach Vergrößerung nicht mehr wesentlich vom Urbild unterscheiden lässt. Hofstadter machte seine Entdeckung ein Jahr bevor Mandelbrot und Feigenbaum in ersten wegweisenden Arbeiten das Konzept des Fraktalen überhaupt formal eingeführt hatten. Hofstadters Regensburger Entdeckung von 1974 stellte einen ersten, weltweit beachteten Höhepunkt seiner erfolg- und facettenreichen Karriere dar. Sie beinhaltet eine bemerkenswerte Metamorphose vom Physiker über den Informatiker bis schließlich zum Kognitionswissenschaftler. Seit 1988 ist Douglas R. Hofstadter Distinguished Professor of Cognitive Science and Computer Science am College of Arts and Sciences der Indiana University Bloomington.
description: Blick in die Wissenschaft, Bd. 27 Nr. 37 (2018): Blick in die Wissenschaft
Additional file 1 of Ambient atmospheric PM worsens mouse lung injury induced by influenza A virus through lysosomal dysfunction
Creators: name: Li, Shunwang
name: Ju, Xiangwu
name: Liu, Qiang
name: Yan, Yiwu
name: Zhang, Cong
name: Qin, Yuhao
name: Deng, Xingyu
name: Li, Chang
name: Tian, Mingyao
name: Zhang, Yanli
name: Jin, Ningyi
name: Jiang, Chengyu
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplementary Material 1: The original full-length blot images for Figure 1B and Figure 3B
sj-pdf-1-uix-10.1177_01617346221099201 – Supplemental material for In Vivo Label-Free Observation of Tumor-Related Blood Vessels in Small Animals Using a Newly Designed Photoacoustic 3D Imaging System
Creators: name: Asao, Yasufumi
name: Nagae, Kenichi
name: Miyasaka, Koichi
name: Sekiguchi, Hiroyuki
name: Aiso, Sadakazu
name: Watanabe, Shigeaki
name: Sato, Marika
name: Kizaka-Kondoh, Shinae
name: Nakajima, Yukari
name: Kishi, Kazuo
name: Yagi, Takayuki
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering

description: Supplemental material, sj-pdf-1-uix-10.1177_01617346221099201 for In Vivo Label-Free Observation of Tumor-Related Blood Vessels in Small Animals Using a Newly Designed Photoacoustic 3D Imaging System by Yasufumi Asao, Kenichi Nagae, Koichi Miyasaka, Hiroyuki Sekiguchi, Sadakazu Aiso, Shigeaki Watanabe, Marika Sato, Shinae Kizaka-Kondoh, Yukari Nakajima, Kazuo Kishi and Takayuki Yagi in Ultrasonic Imaging
Supplemental Material - The association between sodium-glucose cotransporter 2 inhibitors and incident dementia: A nationwide population-based longitudinal cohort study
Creators: name: Siao, Wun-Zhih
name: Lin, Tsung-Kun
name: Huang, Jing-Yang
name: Tsai, Chin-Feng
name: Jong, Gwo-Ping
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Cardiology
subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental Material for The association between sodium-glucose cotransporter 2 inhibitors and incident dementia: A nationwide population-based longitudinal cohort study by Wun-Zhih Siao, Tsung-Kun Lin, Jing-Yang Huang, Chin-Feng Tsai and Gwo-Ping Jong in Diabetes & Vascular Disease Research
Additional file 2 of The application of allelopathy in integrated pest management systems to control temperate European crop pests: a systematic map
Creators: name: Kiely, Charlotte
name: Randall, Nicola
name: Kaczorowska-Dolowry, Magda
Publisher: name: figshare
Year: 2024
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Additional file 2: Derivations from the protocol. A list of methodological derivations from the initial protocol (Kiely and Randall 2022) along with details of additions to and subtractions from the initial coding strategy.
sj-docx-1-ips-10.1177_01925121221092391 – Supplemental material for The domestic democratic peace: How democracy constrains political violence
Creators: name: Veri, Francesco
name: Sass, Jensen
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-docx-1-ips-10.1177_01925121221092391 for The domestic democratic peace: How democracy constrains political violence by Francesco Veri and Jensen Sass in International Political Science Review
Supplemental Material - Why do voters vote for third parties in single member districts? A test of four strategic voting conditions
Creators: name: Tromborg, Mathias
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplementary material for Why do voters vote for third parties in single member districts? A test of four strategic voting conditions by Mathias Tromborg in Party Politics
Effects of Endocrine-Disrupting Compounds (Bisphenol A  and Octhyl Phenol Ethoxylate) on COD Removal Efficiency
Creators: name: DİNÇER, Ali Rıza
name: GÜNEŞ, Yalçın
name: HANCI, Tuğba ÖLMEZ
name: GÜNEŞ, Elçin
name: KHOEI, Shiva
Publisher: name: UIKTEN
Year: 2018
Subjects: Bisphenol-A
Octhyl Phenol Ethoxylate
Biofilm reactor
Inhibition

description: SAR Journal; Vol 1, No 2, 2018. ISSN 2619-9955
description: This study explored the effects of two representative endocrine disrupting compounds (Bisphenol A (BPA) and Octhyl Phenol Ethoxylate (OPEO)) on Chemical Oxygen Demand (COD) removal efficiency. The biofilm reactor was operated at different initial BPA (1.6-15 mg/l) and OPEO (3.01-20.1 mg/l) concentrations. Performances of the process were evaluated in terms of BPA, OPEO degradation and COD removal. Results revealed that 95% of COD removal could be achieved with influent COD and BPA concentrations of 430 mg/L and 1.67 mg/L respectively. The coexistence of BPA (25 mg/l) and OPEO (25 mg/l) resulted in a 64% of COD removal with an initial COD of 542 mg/l. COD removal efficiency was 83% for 3.5 mg/l BPA+3.5 mg/l OPEO, and 64% for 25 mg/l BPA+25 mg/l OPEO indicating a 19% decrease. Rather than the toxic effect of BPA and OPEO, the reduction in COD removal was due to the increase in influent COD values.
Application of Simulation Software in the Production Process of Milled Parts
Creators: name: Dupláková, Darina
name: Telišková, Monika
name: Török, Jozef
name: Paulišin, Dušan
name: Birčák, Jaroslav
Publisher: name: UIKTEN
Year: 2018
Subjects: Simulation
optimization
production process
Witness

description: SAR Journal; Vol 1, No 2, 2018. ISSN 2619-9955
description: In the present, simulation programs are very widespread tool in designing of new systems, improving the existing systems, etc. The simulation software is possible to apply in various sectors, e.g. production, logistics or the field of various services. This article is focused on the application of Witness – simulation software in the manufacturing process. The introduction of this article is focused on short description of simulation issue in the manufacturing processes. The last part of the introduction is focused on description of Witness simulation software. The material and method section describes the manufacturing process (material flow) from which the simulation model is created and subsequently optimized. The final part of this article provides overview of the results from suggested optimization.
Service Quality in Restaurants: Customers’ Expectation and Customers’ Perception
Creators: name: Saneva, Dushica
name: Chortoseva, Sonja
Publisher: name: UIKTEN
Year: 2018
Subjects: service quality
satisfaction
perception
restaurants

description: SAR Journal; Vol 1, No 2, 2018. ISSN 2619-9955
description: The service quality is multidimensional concept which contains a set of diverse attributes grouped in several dimensions. This paper researches the quality of service in restaurants in the Republic of Macedonia. A questionnaire was designed based on three models, SERVQUAL, DINESERV and CFFRSERV, with 29 attributes and distributed in six dimensions. The overall SERVQUAL score is negative. Moreover, all service quality dimensions are with a negative gap, which indicates that the expectation level of service quality in restaurants is higher than the perception level of it.
sj-docx-1-taj-10.1177_20406223221083508 – Supplemental material for Nonalcoholic fatty liver disease and health outcomes: An umbrella review of systematic reviews and meta-analyses
Creators: name: Zhong, Lixian
name: Wu, Chutian
name: Li, Yuting
name: Zeng, Qiuting
name: Lai, Leizhen
name: Chen, Sisi
name: Tang, Shaohui
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Cardiology
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Respiratory Diseases

description: Supplemental material, sj-docx-1-taj-10.1177_20406223221083508 for Nonalcoholic fatty liver disease and health outcomes: An umbrella review of systematic reviews and meta-analyses by Lixian Zhong, Chutian Wu, Yuting Li, Qiuting Zeng, Leizhen Lai, Sisi Chen and Shaohui Tang in Therapeutic Advances in Chronic Disease
EVALUATION OF THE QUALITY OF THE PROCESS BY MEASURING THE INDEX OF OPPORTUNITIES
Creators: name: Bacel Mikhael Alasas
name: Ishkildina, Sofia
name: Zvonov, Sergey
name: Antipov, Dmitriy
name: Ushanova, Natalia
name: Demidenko, Elena
Publisher: name: Center for Quality
Year: 2017
Subjects: quality in engineering
capability index
tolerance limits

description: International Journal for Quality Research; Vol 11, No 2, 2017. ISSN 1800-6450
description: Effective production process management contributes to the competitiveness of a company. If a manufacturer knows customer requirements to produced goods he can define specification levels for a product at each production process. Therefore, a complex index is required which allows to evaluate process quality quantitatively depending on the extent of its shift and dispersion. The tool widely used for assessing process quality is capability index. The analysis presented in the paper shows that this index has two drawbacks: it does not consider costs level and process change dynamics. To solve this problem we introduced two additional indices. One index based on the calculation of economic losses, and the second one considers process change dynamics. Developed quality indices can be applied for the cases when a production process follows the Gaussian law. Moreover, Q index should be used in the cases when the probability of nondefective units production is high.
sj-docx-1-msx-10.1177_10298649221089869 – Supplemental material for Understanding the musical identity and career thinking of postgraduate classical music performance students
Creators: name: López-Íñiguez, Guadalupe
name: Burland, Karen
name: Bennett, Dawn
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Education
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-msx-10.1177_10298649221089869 for Understanding the musical identity and career thinking of postgraduate classical music performance students by Guadalupe López-Íñiguez, Karen Burland and Dawn Bennett in Musicae Scientiae
IMPACT OF QUALITY AND SAFETY PRODUCT ON COMPETITIVENESS
Creators: name: Milovanović, Katarina Kanjevac
Publisher: name: Center for Quality
Year: 2017
Subjects: competitiveness
quality
safety
CE mark
QMS

description: International Journal for Quality Research; Vol 11, No 2, 2017. ISSN 1800-6450
description: This work should indicate how an integrated approach to continuous improvement of quality and safety of products affecting the competitiveness goals as product and company. The impact of Quality Management System (QMS) and compatibility with the requirements of the New Approach Directives (the CE mark) we conducted in three directions.
First we developed a model that includes all the essential steps. By using the modeling method of the complex dynamic system, three macro variables are determined in the model. Each of the macro variables has its structure, variables in the in order to research the practical impact of QMS and CE mark on the competitiveness of enterprises in Serbia, we created a questionnaire on the basis of established models. On the results we apply methods of statistical analysis. In order to further research mentioned impacts on the competitiveness of products in Serbia, we have created a simulation software. This paper presents some of the results that have a dominant impact on competitiveness. From all this we can conclude that the implementation of QMS and CE creates a positive image of the product on the market, and enables the growth of profits and the competitiveness of organization.
57685: Badge: Comrades of the Great War
Creators: name: Project Team, Great War Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Badge belonging to Frank Dowdeswell.
Part of a collection relating to the service of Frank (7th Buffs) and Bob (Army Service Corps) Dowdeswell, of Shaw Green, Prestbury, nr Cheltenham. Bob died in April 1917 after a lorry accident.
Additional file 1 of “It is more isolating to patients if you aren’t familiar with the resources”: a pilot test of a clinician sensitivity training on eating disorders in pregnancy
Creators: name: Khan, Zoya A.
name: Lilly, Christa L.
name: DeFazio, Caterina
name: Claydon, Elizabeth A.
Publisher: name: figshare
Year: 2023
Subjects: Biological Sciences not elsewhere classified
Science Policy

description: Additional file 1. Reference document synthesizing information about eating disorders and pregnancy provided to clinicians with pre and post survey.
Hiv And Malnutrition
Creators: name: Nawan
Publisher: name: Zenodo
Year: 2018
Subjects: HIV

description: Abstract

HIV virus or human immunodeficiency virus has grown and continues to increase worldwide in just 25 years. Ongoing research has been conducted in many countries regarding the development of medications and vaccines, and many funds have been used in the study, however, fully understanding the mechanism of immune depletion is still not possible. The focus is also on improving the quality of life of people living with HIV & AIDS through education, counseling, and nutritional support. Acquired immune deficiency syndrome, or AIDS, is a disease caused by retroviruses, the human immunodeficiency virus (HIV), which attacks and destroys the body's natural defense system against disease and infection. Malnutrition is defined as "a cellular imbalance between the supply of nutrients and energy and the body's need to ensure growth, maintenance, and specific function". People who suffer from malnutrition after contracting HIV are more likely to become AIDS, because their bodies are weak to fight off infections, while good people can cope better with their illnesses. It has been shown that good nutrition increases resistance to infections and diseases, increases energy, thereby making a person stronger and more productive. Knowledge of important nutritional components and incorporating them into the management of people living with HIV is essential in improving the quality of life and better survival of HIV-infected patients.

Key word: HIV & AIDS, Malnutrition, Immune
Additional file 2 of “It is more isolating to patients if you aren’t familiar with the resources”: a pilot test of a clinician sensitivity training on eating disorders in pregnancy
Creators: name: Khan, Zoya A.
name: Lilly, Christa L.
name: DeFazio, Caterina
name: Claydon, Elizabeth A.
Publisher: name: figshare
Year: 2024
Subjects: Biological Sciences not elsewhere classified
Science Policy

description: Additional file 2: Supplementary Table 1. Stratification of outcomes by sex. Supplementary Table 2. Stratification of outcomes by student status.
sj-docx-3-aei-10.1177_15345084221091172 – Supplemental material for A Comparative Investigation of the Rasch/Guttman Scenario Approach: Measuring Learning Motivation Toward Mathematics in Elementary School
Creators: name: Leonid, Parmaksiz
name: Kanonire, Tatjana
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: Education
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental material, sj-docx-3-aei-10.1177_15345084221091172 for A Comparative Investigation of the Rasch/Guttman Scenario Approach: Measuring Learning Motivation Toward Mathematics in Elementary School by Parmaksiz Leonid and Tatjana Kanonire in Assessment for Effective Intervention
sj-docx-1-hij-10.1177_19401612221100418 - Supplemental material for How Do Populists Visually Represent ‘The People’? A Systematic Comparative Visual Content Analysis of Donald Trump and Bernie Sanders’ Instagram Accounts
Creators: name: Moffitt, Benjamin
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-docx-1-hij-10.1177_19401612221100418 for How Do Populists Visually Represent ‘The People’? A Systematic Comparative Visual Content Analysis of Donald Trump and Bernie Sanders’ Instagram Accounts by Benjamin Moffitt in The International Journal of Press/Politics
Supplemental Material - Statutory Threshold Wording is Associated with Child Maltreatment Reporting
Creators: name: Piersiak, Hannah A.
name: Levi, Benjamin H.
name: Humphreys, Kathryn L.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material for Statutory Threshold Wording is Associated with Child Maltreatment Reporting by Hannah A. Piersiak, Benjamin H. Levi, Kathryn L. Humphreys in Child Maltreatment
Prozessorientiertes Qualitätsmanagement in Zeiten der Digitalisierung
Creators: name: Johannsen, Florian
Publisher: name: Blick in die Wissenschaft
Year: 2018

description: Dem prozessorientierten Qualitätsmanagement kommt in Zeiten der Digitalisierung enorme Bedeutung zu. Bedingt durch neue Technologien können Konsumenten sehr einfach Informationen über Produkte, Anbieter oder die günstigsten Angebote einholen und zudem über soziale Plattformen Erfahrungen austauschen. Dies führt dazu, dass sich die Erwartungshaltung der Kunden sehr rasch ändert und Unternehmen ihre Geschäftsprozesse entsprechend anpassen bzw. verbessern müssen, um Konsumenten langfristig zu binden. Allerdings erweist sich die Durchführung von Prozessverbesserungsprojekten in der Praxis oft als herausfordernd, was häufig auf eine mangelhafte Kommunikation bzw. Dokumentation von Projektergebnissen zurückzuführen ist. Aus diesem Grund wurden ein Verbesserungsansatz für Geschäftsprozesse entwickelt und ein Softwaretool realisiert, um Unternehmen bei der zielgerichteten Durchführung von prozessorientierten Qualitätsmanagementprojekten zu unterstützen. Die vorgestellte Lösung trägt maßgeblich zur systematischen Erarbeitung, Dokumentation sowie Kommunikation von Projektergebnissen bei und leistet auf diese Weise einen wichtigen Beitrag für den Erfolg von Prozessverbesserungsinitiativen.
description: Blick in die Wissenschaft, Bd. 26 Nr. 35/36 (2017): Blick in die Wissenschaft
sj-docx-1-inq-10.1177_00469580221093171 – Supplemental material for Classification of Pharmaceutical Policy Measures During the Portuguese Financial Crisis
Creators: name: Donato, António Augusto
name: Pita, João Rui
name: Batel-Marques, Francisco
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-docx-1-inq-10.1177_00469580221093171 for Classification of Pharmaceutical Policy Measures During the Portuguese Financial Crisis by António Augusto Donato, João Rui Rui Pita and Francisco Batel-Marques in INQUIRY: The Journal of Health Care Organization, Provision, and Financing
Additional file 1 of Educational efficacy of medical humanities in empathy of medical students and healthcare professionals: a systematic review and meta-analysis
Creators: name: Zhang, Xin
name: Pang, Hui-fang
name: Duan, Zhiguang
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 1: Appendix 1 Search strategy
sj-docx-2-asj-10.1177_00016993211052079 - Supplemental material for How does parental time relate to social class in a Nordic welfare state?
Creators: name: Ellingsæter, Anne Lise
name: Kitterød, Ragni Hege
name: Hansen, Marianne Nordli
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-2-asj-10.1177_00016993211052079 for How does parental time relate to social class in a Nordic welfare state? by Anne Lise Ellingsæter, Ragni Hege Kitterød and Marianne Nordli Hansen in Acta Sociologica
Additional file 2 of Educational efficacy of medical humanities in empathy of medical students and healthcare professionals: a systematic review and meta-analysis
Creators: name: Zhang, Xin
name: Pang, Hui-fang
name: Duan, Zhiguang
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 2: Appendix 2 Best Evidence Medical Education (BEME) coding scheme for strength of evidence and Kirkpatrick-based outcomes
sj-pdf-1-cps-10.1177_00104140221089644 – Supplemental Material for Social Brokerage: Accountability and the Social Life of Information
Creators: name: Kruks-Wisner, Gabrielle
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material, sj-pdf-1-cps-10.1177_00104140221089644 for Social Brokerage: Accountability and the Social Life of Information by Gabrielle Kruks-Wisner in Comparative Political Studies
Sehen mit einem Zentralskotom
Creators: name: Greenlee, Mark W.
name: Plank, Tina
Publisher: name: Blick in die Wissenschaft
Year: 2018

description: In Deutschland sind schätzungsweise drei Millionen Menschen von der altersabhängigen Makuladegeneration betroffen. Bei der Makuladegeneration wird speziell die zentrale Stelle des schärfsten Sehens auf der Netzhaut zerstört oder geschädigt, was zu einem Sehkraftverlust und damit zur Abnahme der Lesefähigkeit führt. Das Sehen im äußeren Gesichtsfeld bleibt meist erhalten. Im Rahmen einer von der DFG geförderten Forschergruppe (http://www. uni-regensburg.de/FOR1075) befassen wir uns seit 2008 mit den Folgen von zentralen Gesichtsfeldausfällen auf das Gehirn. In Zusammenarbeit mit der Augenklinik des Universitätsklinikums Regensburg untersuchen wir Patienten mit juvenilen Makulaerkrankungen (JMD, vor allem erblichen Netzhautdystrophien, wie z. B. Morbus Stargardt, und Zapfen-Stäbchendystrophie) sowie altersabhängiger Makuladegeneration (AMD) mittels funktioneller Magnetresonanztomographie (fMRT), während sie verschiedene Sehaufgaben absolvieren. Hierbei interessiert uns besonders, inwiefern es aufgrund des durch die Erkrankung entstehenden zentralen Gesichtsfeldausfalls (Zentralskotom) zu Umstrukturierungen in visuellen Arealen des Gehirns kommt, und ob spezielle Trainingsmaßnahmen eine solche Anpassung des Gehirns begünstigen können. In diesem Zusammenhang spielt die neuronale Verarbeitung von Sehreizen in der Sehrinde eine wichtige Rolle.
description: Blick in die Wissenschaft, Bd. 26 Nr. 35/36 (2017): Blick in die Wissenschaft
Stickoxide können auch anders
Creators: name: Schlossmann, Jens
name: Schramm, Andrea
Publisher: name: Blick in die Wissenschaft
Year: 2018

description: Die Emission von gesundheitsgefährdenden Stickoxiden wird derzeit stark diskutiert. Jedoch ist für Stickstoffmonoxid (NO) eine physiologische und therapeutische Rolle seit Längerem bekannt, z. B. bei der Behandlung der Angina pectoris. Für die Aufklärung der kardiovaskulären Funktion von NO wurde 1998 der Nobelpreis an Robert Furchgott, Louis Ignarro und Ferid Murad verliehen. NO könnte bei vielen weiteren Erkrankungen von therapeutischem Nutzen sein. Für die Behandlung von chronischen Nierenerkrankungen (chronic kidney disease, CKD) gibt es bisher wenige therapeutische Ansatzpunkte. In den letzten Jahren hat sich gezeigt, dass NO und seine Signalmoleküle bei CKD ein pharmakologisches Potential haben. In unserer Arbeitsgruppe analysieren wir diesbezüglich sowohl physiologische als auch therapeutische Aspekte von NO und seiner Signalkaskade. Dabei haben sich Stimulatoren der NO-abhängigen löslichen Guanylylzyklasen (sGC), die die Bildung des „Second Messengers“ zyklisches Guanosinmonophosphat (cGMP) induzieren, Hemmstoffe von cGMP-abbauenden Enzymen z. B. der Phosphodiesteras 5 (PDE5) und Serelaxin – die rekombinante Form des Schwangerschaftshormons  Relaxin – als pharmakologische Möglichkeiten ergeben. Damit können möglicherweise CKD wie z. B. Niereninsuffizienz und diabetische Nephropathie behandelt werden.
description: Blick in die Wissenschaft, Bd. 26 Nr. 35/36 (2017): Blick in die Wissenschaft
Additional file 3 of Educational efficacy of medical humanities in empathy of medical students and healthcare professionals: a systematic review and meta-analysis
Creators: name: Zhang, Xin
name: Pang, Hui-fang
name: Duan, Zhiguang
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 3: Appendix 3 Characteristics of included studies
Die unerwartete Kraft des weißen Goldes
Creators: name: Jantsch, Jonathan
Publisher: name: Blick in die Wissenschaft
Year: 2018

description: Fragen des Natriumhaushalts im Menschen beschäftigten bis vor kurzem weder Immunologen noch Infektiologen. Man ging vereinfachend davon aus, dass sich das außerhalb der Zellen befindliche, d. h. extrazelluläre Natrium im Körper gleichmäßig verteilt, so dass die Niere alleine in der Lage ist, die gesamte extrazelluläre Natriumbilanz zu regulieren. Daher glaubte man zu wissen, dass die im Blut gemessenen Natriumkonzentrationen auch die Natriumspiegel in der extrazellulären Flüssigkeit der Gewebe und Organe widerspiegeln. Diese Annahme scheint jedoch eine starke Vereinfachung darzustellen. So hat man beispielsweise herausgefunden, dass es bei natriumreichen Diäten zu einer Natriumanreicherung in der Haut kommen kann. Heute wissen wir, dass Makrophagen – Fresszellen unseres Immunsystems – in der Regulation dieses natriumreichen Mikromilieus eine wichtige, immunphysiologische Rolle spielen, indem sie den Abtransport von Natrium aus der Haut organisieren. Überraschenderweise kann es auch im Kontext von entzündlichen und infektiösen Prozessen zu einer diätunabhängigen Natriumanreicherung im Gewebe kommen, die wiederum die Aktivität und Funktionalität der Immunzellen verändert. So fördert die gesteigerte Natriumverfügbarkeit beispielsweise die Wehrhaftigkeit der Makrophagen gegenüber Infektionserregern. Die lokale Natriumbilanz stellt somit eine neue, bisher unterschätzte Stellgröße des Immunsystems dar, die Einfluss auf die Infektionsabwehr und Immunphysiologie nimmt.
description: Blick in die Wissenschaft, Bd. 26 Nr. 35/36 (2017): Blick in die Wissenschaft
Politik macht Kleidung?
Creators: name: Burgemeister, Melanie
Publisher: name: Blick in die Wissenschaft
Year: 2018

description: Kleidung ist ein wichtiges gesellschaftliches Ausdrucksmittel. Die Möglichkeit, sich über sie zu präsentieren, ist dabei oftmals wichtiger als die Bedeckung und der Schutz des eigenen Körpers es sind. Mit Kleidung können durch Symbole, Trageweisen und Materialien gezielt Zeichen an die Umwelt übermittelt werden. Diese ‚nonverbale‘ Kleidersprache war jedoch nicht immer frei nutzbar. Über Jahrhunderte regelten Gesetze, was die Menschen tragen durften. Auch gegenwärtig wird Kleidung und die damit verbundene ‚angemessene‘ Bedeckung des Körpers wieder politisch verhandelt. Damit widmet sich die Diskussion um ein Verhüllungsverbot einem Problemfeld, das bereits im Spätmittelalter nachweisbar ist. Die Gründe für die gesetzliche Begrenzung der Kleidung in der Vergangenheit wurden in der Forschung oft auf die Sicherung etablierter Standesgrenzen reduziert. Doch betrachtet man die zahlreichen Detailregulierungen der Ordnungen in ihrem jeweiligen Kontext, so ist diese monokausale Antwort unbefriedigend. Gerade sittlich-religiöse Vorschriften in den Kleiderordnungen belegen eine andere Ausrichtung. Es stellt sich somit die Frage, welche Motivationen hinter diesen Gesetzen standen und was sie für die Betroffenen bedeuteten: eine Form der Disziplinierung von oben oder eine Anleitung, die Orientierung in einer sich wandelnden Welt gab? Dabei ist nicht zuletzt auch das Aussehen der akzeptierten Kleidung am Ende des Mittelalters von Bedeutung. Der Erforschung dieses Themas widmet sich mein Promotionsvorhaben.
description: Blick in die Wissenschaft, Bd. 26 Nr. 35/36 (2017): Blick in die Wissenschaft
Additional file 4 of Educational efficacy of medical humanities in empathy of medical students and healthcare professionals: a systematic review and meta-analysis
Creators: name: Zhang, Xin
name: Pang, Hui-fang
name: Duan, Zhiguang
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 4: Appendix 4 BEME and Kirkpatrick-based results
Kommunistenprozesse
Creators: name: Löhnig, Martin
Publisher: name: Blick in die Wissenschaft
Year: 2018

description: Die Bundesrepublik Deutschland hat sich zum 30. August 1951 ein Staatsschutzstrafrecht gegeben, §§ 80 ff. StGB; dies geschah ersichtlich vor dem Hintergrund eines vorherrschenden Gefühls akuter Bedrohung durch den Kommunismus. Das Vorgängerrecht, die 1934 erlassenen Bestimmungen zum Schutz des nationalsozialistischen Staates, war durch das Kontrollratsgesetz Nr. 1 vom 20. September 1945 aufgehoben worden. Regelungen zum strafrechtlichen Schutz von Staat und Verfassung gehören ganz selbstverständlich zum Normenbestand jedes Staatswesens. Zumal zum Normenbestand einer wehrhaften Demokratie, die diese zweite deutsche Republik nach den Erfahrungen der Weimarer Jahre sein wollte. Allerdings bergen solche Regelungen stets auch Gefahren. Denn sie ermöglichen auch politische Justiz in dem Sinne, dass die regierende Mehrheit politische Dissidenz oder Gegnerschaft zum Verbrechen stempeln und auf diese Weise die Meinungskonkurrenz im gesellschaftspolitischen Diskurs beeinflussen kann.
description: Blick in die Wissenschaft, Bd. 26 Nr. 35/36 (2017): Blick in die Wissenschaft
Börsenkurse und Schlachtenglück
Creators: name: Jopp, Tobias A.
Publisher: name: Blick in die Wissenschaft
Year: 2018

description: Wie lässt sich die in einer größeren Gruppe von Individuen, vielleicht sogar in der gesamten Bevölkerung, vorherrschende Wahrnehmung eines einzelnen Ereignisses oder einer Abfolge von Ereignissen messen, wenn keine modernen Umfragedaten vorliegen? Gerade in der Auseinandersetzung mit in der Vergangenheit weiter zurückliegenden Phänomenen stellt die Unmöglichkeit, Massenumfragen durchzuführen, den Historiker vor echte Herausforderungen. Die im Folgenden vorgestellte Forschungsarbeit unternimmt für die Phase des Ersten Weltkriegs den Versuch, genau dieses Manko an Informationen über die zeitgenössische Wahrnehmung von Ereignissen – Schlachten, Begegnungen, Gesetzen etc. – abzubauen. Es wird darum gehen, wie man aus massenhaft vorliegenden Kapitalmarktdaten – konkret Börsenkursen von Wertpapieren – Aussagen über die Investorenwahrnehmung des Kriegsverlaufs ableiten kann. Auch wenn deren Meinung sicherlich nicht repräsentativ für eine ganze Bevölkerung sein kann, so sollte sie dennoch weniger patriotisch gefärbt und deren Analyse gerade deswegen erhellend sein; an der Börse geht es schließlich ganz nüchtern ums Geldverdienen.
description: Blick in die Wissenschaft, Bd. 26 Nr. 35/36 (2017): Blick in die Wissenschaft
Additional file 1 of Create to Collaborate: using creative activity and participatory performance in online workshops to build collaborative research relationships
Creators: name: Malpass, Alice
name: Breel, Astrid
name: Stubbs, Jo
name: Stevens, Tassos
name: Maravala, Persis-Jadé
name: Shipman, Ellie
name: Banks Gross, Zoe
name: Farr, Michelle
Publisher: name: figshare
Year: 2023
Subjects: Biotechnology
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 1. Observation template and interview topic guide.
57711: Dickie New shot in the legs
Creators: name: Project Team, Great War Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Arthur Josiah Wheatley, of the 2nd Worcesters (father of Pamela Barnard) used to recall a soldier called Dickie New. When they went over the top together they all dropped to the ground to escape the machine gun fire. Dickie New, always a clumsy man, had h
66047: First Time In ['After the dread...']
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Manuscript in pen in Marion Scott's hand. Various versions of the poem exist.
Synthesis and polyester printing applications of transition metal complexes of tridentate 5-(m-tolyldiazenyl)salicylaldehyde thiosemicarbazone derivatives
Creators: name: Darwish, Shaban A.
name: Aish, Emad H.
name: Elkhabiry, Shaban A.
name: Abbas, Samir Y.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biophysics
Biochemistry
Physical Sciences not elsewhere classified
Chemical Sciences not elsewhere classified

description: Thiosemicarbazone metal complexes are intriguing molecules with a variety of applications in several fields, including the pharmaceutical sector, analytical chemistry, and textile industries. Here, we designed and synthesized 12 transition metal complexes based on thiosemicarbazone as a tridendate group and azo moiety as a chromophore part, in addition to evaluating their color strength and fastness properties. The tridentate ligand derivatives of 5-(m-tolyldiazenyl)salicylaldehyde thiosemicarbazone reacted with four transition metal salts (copper, cobalt, nickel, and iron salts) in refluxing alkaline ethanol to afford the corresponding thiosemicarbazone complexes. The ligands behaved as double-deprotonated tridentate ligands that connected to the transition metal ions through the deprotonation of phenolic-OH and thiol-SH, as well as the azomethine nitrogen atom, to generate fused five- and six-membered heterocycle rings. The obtained metal complexes were characterized by elemental analyses, atomic absorption, IR, and UV–Vis spectra. The color strength and fastness properties of the printed fabrics were tested, showing good to excellent properties.
Additional file 2 of An investigation of psychoactive polypharmacy and related gender-differences in older adults with dementia: a retrospective cohort study
Creators: name: Trenaman, Shanna C
name: Quach, Jack
name: Bowles, Susan K
name: Kirkland, Susan
name: Andrew, Melissa K
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Mental Health

description: Supplementary Material 2
Additional file 2 of Create to Collaborate: using creative activity and participatory performance in online workshops to build collaborative research relationships
Creators: name: Malpass, Alice
name: Breel, Astrid
name: Stubbs, Jo
name: Stevens, Tassos
name: Maravala, Persis-Jadé
name: Shipman, Ellie
name: Banks Gross, Zoe
name: Farr, Michelle
Publisher: name: figshare
Year: 2024
Subjects: Biotechnology
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 2. GRIPP 2 Short form.
In silico and in vitro inhibition abilities of novel benzene sulfonamides on carbonic anhydrase and choline esterases
Creators: name: Surgun, Sevgi
name: Öztaşkın, Necla
name: Çağan, Ahmet
name: Akıncıoğlu, Akın
name: Akıncıoğlu, Hülya
name: Göksu, Süleyman
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Compounds that possess a benzene sulfonamide structure are utilized in a wide range of fields. It is reported in the literature that many compounds belonging to this class of compounds exhibit various pharmacological properties such as antibacterial, antifungal, antiviral, anticancer, inflammatory, antiglaucoma, and anticholinergic effects. Carbonic anhydrase (CA) enzymes play a critical role in pH regulation, long-term synaptic turnover and are therefore thought to be associated with such diseases as mental retardation, Alzheimer’s disease (AD) and Down syndrome. Studies have reported that there is an increase in the levels of hCA-I and hCA-II isoenzymes in AD. AD is a complex, multifactorial disorder, so therapy should probably address not only the cholinergic system but also additional systems. Based on these features, a series of novel substituted benzene sulfonamides were synthesized from 1,2,3-trimethoxy-5-methylbenzene. Sulfonyl chloride 9 was synthesized from the reaction of 1,2,3-trimethoxy-5-methylbenzene and excess chlorosulfonic acid. The reaction of the obtained sulfonyl chloride with NH3 and N-alkyl amines, aniline, and phenethylamine gave substituted benzene sulfonamide derivatives 10–16. The synthesized compounds were evaluated for their carbonic anhydrase (hCA I-II), acetyl cholinesterase (AChE) and butyryl cholinesterase (BChE) inhibitory properties. Some of the substituted benzene sulfonamide derivatives 10–16 showed inhibitory effect on hCA isoenzymes. The Ki values determined for the hCA I enzyme are in the range of 102.01–147.19 µM. Benzene sulfonamide derivatives 10–16 showed an inhibitory effect on AChE and BChE. The Ki values determined for AChE and BChE enzymes are in the range of 28.76–308.08 µM and 42.80–445.60 µM, respectively. It was determined that sulfonamides 15–16 were selective inhibitors for the hCA I and 10 showed 11-fold more selectivity on AChE than BChE. In addition, the in-silico SAR and ADME properties of the synthesized compounds were also investigated.
Synthesis, structural characterization of phenoxo-bridged zinc(II) complexes and their binding interaction with the spike protein of SARS-CoV-2
Creators: name: Banerjee, Bhaskar
name: Ali, Afsar
name: Verma, Rajaneesh K.
name: Guin, Mridula
name: Sharma, Pooja
name: Chakravorty, Tanmoy
name: Jagannath, S. P.
name: Asatkar, Ashish K.
name: Srivastava, Vivek
name: Yadav, Ankush
name: Verma, Vinay K.
name: Singh, Ram Chandra
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biophysics
Biochemistry
Biotechnology
Chemical Sciences not elsewhere classified
Computational Biology

description: The research article reports the synthesis and structural study of the optimized geometry of selenium (Se) bearing 24- and 28- membered macrocyclic Schiff bases, LaH2, LbH2 and their reactions with zinc metal ion. The reactions of the macrocyclic Schiff bases with ZnCl2 in 1:2 molar ratios result in the formation of bimetallic Zn(II) complexes having molecular composition [Se{(CH2)2N = CPh(4-CH3-C6H2O) PhC = O}2 · Zn2Cl2], (1) and [Se{(CH2)3N = CPh(4-CH3-C6H2O)PhC = O}2 · Zn2Cl2], (2). Moreover, as confirmed by various physico-chemical techniques such as elemental analysis, UV–Vis, FTIR,1H NMR, and mass spectrometry, the proligands underwent partial hydrolytic cleavage at one of the C = N positions and behave like hexadentate (N2O4) ligands binding to two Zn(II) ions via bridging through the Ophenolic atoms, which results in a square pyramidal geometry around Zn(II) with the chlorine atom occupying axial positions. Further, following density functional study, the stable optimized configuration of the Schiff bases LaH2 and LbH2 is found to adopt bowl shape geometry. Conversely, in molecular docking studies, the synthesized complex 1 exhibits a significantly stronger binding affinity (−8.7 kcal/mol) to the spike protein of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) as compared to the common coronavirus disease 2019 (COVID-19) treatment drugs such as chloroquine, hydroxychloroquine, and remdesivir with activity percentage showing more than 20% overall effectiveness than remdesivir and thus indicating its potential for COVID-19 therapeutics.
From Insights to Action: Enriching the Clinical Research Workforce by Developing Diverse and Inclusive Career Programs
Creators: name: Ruiz, Raquel
name: Schwartz, Ann
name: Lackey, Russell
name: Long, Teresa
name: Dozier, Ann
name: Ossip, Deborah
name: Zand, Martin S.
Publisher: name: Zenodo
Year: 2020
Subjects: CTSA, Common Metrics

description: The Center for Leading Innovation and Collaboration Common Metrics team releases From Insights to Action: a resource for organizing research programs with an equity and inclusive lens. This is a collection of approaches from across the Clinical and Translational Science consortium. The aim of this report is to provide research programs with actionable strategies for enhancing the diversity of our future scientific workforce.
description: The University of Rochester Center for Leading Innovation and Collaboration (CLIC) is the coordinating center for the Clinical and Translational Science Awards (CTSA) Program, funded by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH), Grant U24TR002260.
Epidemiology of healthcare-associated infections due to Pseudomonas aeruginosa: serotyping,molecular typing, study of antibiotic resistance and detection of resistance genes
Creators: name: Dalel Elhani
name: Asli, Mohamed S.
name: R. Ben Helal
name: Barguellil, Farouk
Publisher: name: F1000Research
Year: 2017

description: In this work, our objectives are intended to establish an epidemiological link between strains of Pseudomonas aeruginosa collected in clinical wards, we used different methods of typing : Phenotypic methods, antibiotyping and serotyping, genotypic methods: Rep-PCR. Our study was completed by searching for carbapenemases genes.
Distributed System Behavior Modeling of Urban Systems with Ontologies, Rules and Message Passing Mechanisms
Creators: name: Montezzo Coelho, Maria Eduarda
Publisher: name: Digital Repository at the University of Maryland
Year: 2017
Subjects: subject: Civil engineering
subject: FOS: Civil engineering
subject: Urban planning
subject: Systems science
subject: cascading failures
subject: city operating system
subject: semantic modeling
subject: spacio-temporal modeling
subject: system of systems
subject: urban modeling

description: Modern infrastructures are deﬁned by spatially distributed network structures, concurrent subsystem-level behaviors, distributed control and decision making, and interdependencies among subsystems that are not always well understood. This work presents a model of system-level interactions that simulates distributed system behaviors through the use of ontologies, rules checking, and message passing mechanisms. We take initial steps toward the behavior modeling of large-scale urban networks as collections of networks that interact via many-to-many association relationships. We conclude with ideas for scaling up the simulations with mediators assembled from Apache Camel technology.
54679: Photograph of John Clarke Morten
Creators: name: Project Team, Great War Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: A photograph of my father-in-law. It is one he likes - there were many that did not come up to his expectations! He looks very proud in this one.Editor's Comment:
Pte. 2393 John Clarke Morten, 1/7th Bn. Manchester Regiment, was commissioned Second Lieutenant and later attached to the Royal Air Force.
Novel phosphorus-doped molybdenum carbide catalyst for the reverse water-gas shift reaction
Creators: name: Shi, Xiaofeng
name: Wang, Zhimeng
name: Rong, Qingshan
name: Cao, Kexin
name: Shi, Yan
name: Yao, Zhiwei
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine

description: The effect of phosphorus on the catalytic performance of molybdenum carbide for the reverse water-gas shift (RWGS) reaction was studied for the first time. It was found that the catalytic activity and selectivity of the P-doped molybdenum carbide catalysts were greatly related to their P/Mo molar ratios within a narrow range (0–0.1). It was obvious that increasing P/Mo molar ratio led to a decreased activity, but can effectively enhance selectivity. The P-doped molybdenum carbide with a P/Mo molar ratio of 0.05 was proposed to be more excellent than other P-doped molybdenum carbides in terms of both activity and selectivity, which was attributed to its higher oxophilicity and weaker affinity toward CO.