cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Untersuchungen von Kontaktöffnungs-Entladungen in einem zündfähigen H2-Luft-Gemisch im Bereich niedriger Spannungen
Creators: name: Uber, Carsten
name: Hilbert, Michael
Publisher: name: Physikalisch-Technische Bundesanstalt (PTB)
Year: 2019
Subjects: Explosionsschutz
Eigensicherheit
Kontaköffnungsfunken
IEC
Entladungen

description: Dies ist ein Beitrag für das 15. BAM-PTB-Kolloquium zur chemischen und physikalischen Sicherheitstechnik am 21. und 22. Mai 2019 bei der PTB in Braunschweig.
description: Elektrische Entladungen, die bei öffnenden elektrischen Kontakten wie beispielsweise beim Ziehen einer Steckverbindung auftreten können, sind eine Zündquelle in explosiven Atmosphären. In der Zulassungspraxis werden solche Entladungen im sogenannten IEC-Funkenprüfgerät zur Prüfung nach dem Zündschutzkonzept „i“ Eigensicherheit erzeugt. Die stark streuenden Ergebnisse dieses Gerätes und die noch nicht vollständig verstandene Physik der Kontaktvorgänge erfordern eine verbesserte Prüfmethode. Diese soll die für die Zündung relevante elektrische Entladung an der Zündgrenze nachbilden, um diese reproduzierbarer bestimmen zu können. Für die Analyse der physikalischen Vorgänge, die zur Zündung führen, ist eine spezielle Kontaktvorrichtung entwickelt worden. Damit können die Entladungen > 200 µm Länge und mit einer Dauer von > 500 µs an einer bestimmbaren Position erzeugt und untersucht werden. Für die Entladungen an der Zündgrenze bei niedrigen Spannungs- und Stromwerten (max. 30 V, 30 bis 100 mA Konstantstrombegrenzung) sind die Bedingung für die Erzeugung ermittelt worden. Das sind die Rauheit auf der Kontaktoberfläche, die langsame Kontaktöffnungsbewegung und eine geeignet regelnde Spannungsquelle mit Konstantstrombegrenzung. Damit sind für diese Entladungen an der Zündgrenze die Strom-Spannungs-Kennlinie, das Spektrum mit dominierenden Linien von Cadmium-Metalldampf sowie die Temperaturverläufe ermittelt worden.
Robust Dynamical Decoupling Sequences for Individual Nuclear Spin Addressing
Creators: name: Casanova, J.
name: Wang, Z. -Y.
name: Haase, J. F.
name: Plenio, M. B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose the use of non-equally spaced decoupling pulses for high-resolution selective addressing of nuclear spins by a quantum sensor. The analytical model of the basic operating principle is supplemented by detailed numerical studies that demonstrate the high degree of selectivity and the robustness against static and dynamic control field errors of this scheme. We exemplify our protocol with an NV center-based sensor to demonstrate that it enables the identification of individual nuclear spins that form part of a large spin ensemble.
description: 5 pages, 4 figures
Measuring stability of virus in aerosols under varying environmental conditions
Creators: name: Oswin, Henry P.
name: Haddrell, Allen E.
name: Otero-Fernandez, Mara
name: Cogan, Tristan A.
name: Mann, Jaime F. S.
name: Morley, Catherine H.
name: Hill, Darryl J.
name: Davidson, Andrew D.
name: Finn, Adam
name: Thomas, Richard J.
name: Reid, Jonathan P.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Copyright © 2021 American Association for Aerosol Research
Gymnocalycium eurypleurum F. Ritter, Kakt. Sudamer.
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Caryophyllales
Cactaceae
Gymnocalycium
Gymnocalycium eurypleurum

description: Gymnocalycium eurypleurum F.Ritter, Kakt. Südamer. 1: 268. 1979.
Succulent herb.
 Vouchers: Alto Paraguay: Schinini 17823 (CTES).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
IgG-Immune Complexes Promote B Cell Memory by Inducing BAFF
Creators: name: Vilen, Barbara J.
name: Kang, Sunah
name: Jones, Shannon Z.
name: Rathmell, Jeffrey C.
name: Keener, Amanda B.
name: Whitmire, Jason K.
name: Caro-Maldonado, Alfredo
name: Clarke, Stephen H.
name: Matsushima, Glenn K.
name: Benschop, Robert J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Memory B cell responses are vital for protection against infections, but must also be regulated to prevent autoimmunity. Cognate T cell help, somatic hypermutation, and affinity maturation within germinal centers (GCs) are required for high affinity memory B cell formation; however, the signals that commit GC B cells to the memory pool remain unclear. In this study, we identify a role for IgG immune complexes (ICs), FcγRs, and BAFF during the formation of memory B cells in mice. We found that early secretion of IgG in response to immunization with a T-dependent antigen leads to IC-FcγR interactions that induce DCs to secrete BAFF which acts at or upstream of Bcl-6 in activated B cells. Loss of CD16, hematopoietic cell-derived BAFF, or blocking IC:FcγR regions in vivo diminished the expression of Bcl-6, the frequency of GC and memory B cells, and secondary antibody responses. BAFF also contributed to the maintenance and/or expansion of the Tfh population, although it was dispensable for their formation. Thus, early antibody responses contribute to the optimal formation of B cell memory through IgG-ICs and BAFF. Our work defines a new role for FcγRs in GC and memory B cell responses.
LAG-3 Confers a Competitive Disadvantage upon Antiviral CD8 + T Cell Responses
Creators: name: Whitmire, Jason K.
name: Cook, Kevin D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Ongoing clinical trials are evaluating the benefits of systemic blockade of lymphocyte activation gene-3 (LAG-3) signals to improve immunity to tumors. Those studies are founded on the well-established inhibitory role of LAG-3 in regulating CD8+ T cells during chronic virus infection and anti-tumor responses. However, the T cell response in LAG-3 deficient mice is similar in size and function to that in wild type animals, suggesting LAG-3 has nuanced immune-regulatory functions. We performed a series of adoptive transfer experiments in mice to better understand the T cell-intrinsic functions of LAG-3 in the regulation of CD8+ T cell responses. Our results indicate that LAG-3 expression by CD8+ T cells inhibits their competitive fitness and results in a slightly reduced rate of cell division in comparison to LAG-3 deficient cells. This cell-intrinsic effect of LAG-3 was consistent across both acute and chronic virus infections. These data show that LAG-3 directly modulates the size of the T cell response and support the use of LAG-3 blockade regimens to enhance CD8+ T cell responses.
Berechnung der Explosionsbereiche von Alkoholen, Ketonen und halogenierten Kohlenwasserstoffen im Gemisch mit Inertgasen
Creators: name: Askar, Enis
name: Abdelkhalik, Aksam
name: Markus, Detlev
name: Stolz, Thomas
name: Brandes, Elisabeth
Publisher: name: Physikalisch-Technische Bundesanstalt (PTB)
Year: 2019
Subjects: Explosionsschutz
Explosionsbereich
Dreistoffgemische
Inertisierung

description: Dies ist ein Beitrag für das 15. BAM-PTB-Kolloquium zur chemischen und physikalischen Sicherheitstechnik am 21. und 22. Mai 2019 bei der PTB in Braunschweig.
description: Die Explosionsbereiche für Dreistoffsysteme aus Brennstoff, Inertgas und Luft wurden nach dem Modell der konstanten adiabatischen Flammentemperaturprofile berechnet. Für die Parametrisierung des halbempirischen Modells muss der Explosionsbereich für ein bestimmtes Dreistoffsystem aus Brennstoff, Inertgas und Luft bekannt sein. Dann lassen sich Explosionsbereiche desselben Brennstoffs mit einem beliebigen Inertgas und bei einer beliebigen Temperatur berechnen. Ergänzend zu früheren Arbeiten, in denen die Explosionsbereiche für Brenngase aus der homologen Reihe der Alkane und Alkene berechnet worden sind, wurden nun die Berechnungen für 1-Propanol, Aceton und Difluormethan durchgeführt. Als Inertgase wurden neben Stickstoff und Kohlendioxid auch die Edelgase Argon und Helium berücksichtigt. Für die Berechnung der Explosionsbereiche in Systemen mit Helium, ist das Modell erweitert worden, so dass auch die Transporteigenschaften (d.h. Wärmeleitfähigkeit, Diffusionskoeffizient) der Komponenten berücksichtigt werden. Weiterhin ist eine Möglichkeit zur praxisnahen Berechnung der Spitze des Explosionsbereichs implementiert worden. Die Ergebnisse zeigen insgesamt, dass die Berechnung der Explosionsbereiche für Alkohole, Ketone und halogenierte Kohlenwasserstoffe mit ähnlicher Genauigkeit wie für Alkane und Alkene möglich ist. Die vorgenommenen Modifikationen sind geeignet, um auch eine Berechnung für Gasgemische mit Helium durchzuführen, dessen starke inertisierende Wirkung im Vergleich zu den Inertgasen Argon oder Stickstoff vor allem auf den stark unterschiedlichen Transporteigenschaften beruht. Für die Analyse der physikalischen Vorgänge, die zur Zündung führen, ist eine spezielle Kontaktvorrichtung entwickelt worden. Damit können die Entladungen > 200 µm Länge und mit einer Dauer von > 500 µs an einer bestimmbaren Position erzeugt und untersucht werden. Für die Entladungen an der Zündgrenze bei niedrigen Spannungs- und Stromwerten (max. 30 V, 30 bis 100 mA Konstantstrombegrenzung) sind die Bedingung für die Erzeugung ermittelt worden. Das sind die Rauheit auf der Kontaktoberfläche, die langsame Kontaktöffnungsbewegung und eine geeignet regelnde Spannungsquelle mit Konstantstrombegrenzung. Damit sind für diese Entladungen an der Zündgrenze die Strom-Spannungs-Kennlinie, das Spektrum mit dominierenden Linien von Cadmium-Metalldampf sowie die Temperaturverläufe ermittelt worden.
Cuscuta longiloba Yunck., Svensk Bot. Tidskr.
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Solanales
Convolvulaceae
Cuscuta
Cuscuta longiloba

description: Cuscuta longiloba Yunck., Svensk Bot. Tidskr. 55: 229. 1961.
Vine.
 Vouchers: Alto Paraguay: Rojas 13877, type (S).
 Evolvulus chamaepitys Mart. var. paraguayensis Ooststr., Meded. Bot. Mus. Herb. Rijks Univ. Utrecht 14: 206. 1934.
Herb.
 Vouchers: Amambay: Hassler 11103, type (B, BM, K, P, S, U); Hassler 11103a, type (B, BM, K, NH, NY, S); Soria 5655 (FCQ).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Nrf2 Modulates Host Defense during Streptococcus pneumoniae Pneumonia in Mice
Creators: name: Gomez, John C.
name: Dang, Hong
name: Martin, Jessica R.
name: Doerschuk, Claire M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Nrf2 regulates the transcriptional response to oxidative stress. These studies tested the role of Nrf2 during S. pneumoniae pneumonia and identified Nrf2-dependent genes and pathways in lung tissue and in recruited neutrophils. Nrf2 null and WT mice were studied at 6 and 24 h following instillation of S. pneumoniae or PBS. At 6 h, fewer neutrophils were recruited and the number of bacterial remaining in the lungs tended to be less (p=0.06) in the Nrf2 null compared to WT mice. In uninfected lungs, 53 genes were already differentially expressed in Nrf2 null compared to WT mouse lungs and gene sets involved in phagocytosis, Fc receptor function, complement and immunoglobulin regulation are enhanced in PBS-treated Nrf2 null gene profiles compared to those of WT mice. These results suggest that initial host defense is enhanced in Nrf2 null mice, resulting in less recruitment of neutrophils. At 24 h, neutrophil recruitment was greater. The percentages of early apoptotic and late apoptotic/necrotic neutrophils were similar. At increasing inoculum numbers, mortality strikingly increased from 15% to 31% and 100% in Nrf2 null mice, whereas all WT mice survived, and Nrf2 null mice had a defect in clearance, particularly at the intermediate dose. The mortality was due to enhanced lung injury and greater systemic response. Gene profiling identified differentially regulated genes and pathways in neutrophils and lung tissue, including those involved in redox stress response, metabolism, inflammation, immunoregulatory pathways and tissue repair, providing insight into the mechanisms for the greater tissue damage and increased neutrophil accumulation.
Asteroids in GALEX: Near-ultraviolet photometry of the major taxonomic groups
Creators: name: Waszczak, Adam
name: Ofek, Eran O.
name: Kulkarni, Shrinivas R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present ultraviolet photometry (NUV band, 180--280 nm) of 405 asteroids observed serendipitously by the Galaxy Evolution Explorer (GALEX) from 2003--2012. All asteroids in this sample were detected by GALEX at least twice. Unambiguous visible-color-based taxonomic labels (C type versus S type) exist for 315 of these asteroids; of these, thermal-infrared-based diameters are available for 245. We derive NUV-V color using two independent models to predict the visual magnitude V at each NUV-detection epoch. Both V models produce NUV-V distributions in which the S types are redder than C types with more than 8-sigma confidence. This confirms that the S types' redder spectral slopes in the visible remain redder than the C types' into the NUV, this redness being consistent with absorption by silica-containing rocks. The GALEX asteroid data confirm earlier results from the International Ultraviolet Explorer, which two decades ago produced the only other sizeable set of UV asteroid photometry. The GALEX-derived NUV-V data also agree with previously published Hubble Space Telescope (HST) UV observations of asteroids 21 Lutetia and 1 Ceres. Both the HST and GALEX data indicate that NUV band is less useful than u band for distinguishing subgroups within the greater population of visible-color-defined C types (notably, M types and G types).
description: 13 pages, 11 figures, accepted 2015-May-6 to The Astrophysical Journal. Includes one machine-readable table of NUV asteroid detections. Version 2 includes a corrected citation to Waszczak et al. (2015) arXiv abstract
Druckgasbehälter im Feuer - Auswirkungen im Versagensfall
Creators: name: Tschirschwitz, Rico
name: Krentel, Daniel
name: Kluge, Martin
Publisher: name: Physikalisch-Technische Bundesanstalt (PTB)
Year: 2019
Subjects: Explosionsschutz
Druggasbehälter
Unterfeuerungsversuche
Behälterversagen

description: Dies ist ein Beitrag für das 15. BAM-PTB-Kolloquium zur chemischen und physikalischen Sicherheitstechnik am 21. und 22. Mai 2019 bei der PTB in Braunschweig.
description: Es wurden insgesamt 57 Einzelversuche zum Versagen von Druckgasbehältern durchgeführt. Untersucht wurden dabei 11-kg-Propangasflaschen, PKW-Radmuldentanks für LPG sowie CNG-Tanks vom Typ III (Compositetanks mit Aluminiumliner) und Typ IV (Compositetanks mit Polymerliner). Mit 18 hydraulischen Berstversuchen wurde das Versagensverhalten unter kalten Bedingungen charakterisiert. In 39 Unterfeuerungsversuchen mit den gefüllten LPG- und CNG-Tanks, davon 36 mit Tanks ohne Sicherheitseinrichtung, wurde das Behälter¬ver¬sagen durch Brandbeaufschlagung untersucht. Neben verschiedenen Behältermantel¬temperaturen und dem Behälterinnendruck wurde auch die Temperatur des gespeicherten Mediums dokumentiert. Dadurch war es möglich, genau zu dokumentieren, unter welchen Bedingungen und bei welchem Zustand der Behälter versagt hat. In einem Großteil der Unterfeuerungsversuche mit Behältern ohne Sicherheitseinrichtungen kam es zur Bildung eines Feuerballs, einer massiven Druck- und Temperaturwirkung auf den Nahbereich sowie einer Vielzahl von Fragmenten im Nah- und Fernbereich. In einer Entfernung von l = 7 m wurden Überdrücke von bis zu p = 0,41 bar gemessen. In 30 Unterfeuerungsversuchen kam es zur Fragmentierung des Behälters. Dabei konnten 159 Fragmente mit Wurfweite und Masse dokumentiert werden. Die dabei maximal festgestellte Wurfweite eines Fragments lag bei l = 311 m.
Overlapping IgG4 Responses to Self- and Environmental Antigens in Endemic Pemphigus Foliaceus
Creators: name: Rivitti, Evandro A.
name: Hans-Filhio, Gunter
name: Qian, Ye
name: Aoki, Valeria
name: Dang, Bim
name: Valenzuela, Jesus G.
name: S. Jeong, Joseph
name: Abdeladhim, Maha
name: Diaz, Luis A.
name: Ye, Jian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The etiology of human autoimmune diseases in general remains largely unknown, although the genetic and environmental interplay may be relevant. This applies to the autoimmune diseases of the skin such as the pemphigus phenotypes and others. In this group, there is an endemic form of pemphigus foliaceus [also known as Fogo Selvagem (FS)] where the pathogenic IgG4 autoantibody response to the self-antigen, Desmoglein 1 (Dsg1) cross-react with the LJM11 sand fly salivary gland antigen. In this investigation we dissected the IgG4 autoantibody repertoires utilized by FS patients in response to endogenous self Dsg1 and exogenous LJM11 sand fly antigen. Based on analyses of the genetic clonal signatures of these antibodies, our results indicate that there is a significant overlap between these two responses as all identified IgG4 monoclonal antibodies cross-react to both Dsg1 and LJM11 antigens. Germline H and L chain V gene antibodies generated according to mutated cross-reactive monoclonal antibodies preserved their reactivity to both antigens. Our findings suggest that both Dsg1 autoantigen and LJM11 environmental antigen could be the initial antigenic stimulants for the IgG4 autoimmune responses in FS. These results support our hypothesis that LJM11 antigen plays a substantial role in triggering the IgG4 autoantibody development in FS, and provide new insights on how non-infectious environmental antigen(s) may drive the generation of autoantibodies in IgG4-related autoimmune diseases.
Analysis of a permanent magnet synchronous machine used in hazardous location
Creators: name: Yogal, Nijan
name: Lehrmann, Christian
Publisher: name: Physikalisch-Technische Bundesanstalt (PTB)
Year: 2019
Subjects: explosion protection
permanent magnet synchronous machine
test method development
uncertainty assessment

description: Dies ist ein Beitrag für das 15. BAM-PTB-Kolloquium zur chemischen und physikalischen Sicherheitstechnik am 21. und 22. Mai 2019 bei der PTB in Braunschweig.
description: The use of a permanent magnet synchronous machines (PMSMs) to achieve high performance and high energy efficiency in modern industrial technology has increased rapidly in recent decades. Similarly, the demand for PMSMs in hazardous locations has been increasing as well. This work focuses on the safe operation of PMSMs in hazardous locations, as it undergoes through a series of mechanical, electrical and thermal tests. These tests methods ensure that no hot surfaces, electrical arcs or sparks occur during normal or possible failure operation. In addition, it ensures that there are no possible failure conditions in all inner and outer parts of the PMSMs that can lead to high energy which may be responsible for ignition. The PMSM installed in hazardous areas need to have protection against the possibility of ignition. Therefore, the thermal protection of the PMSM using PTC thermistors sensors are tested so that the PMSM stops operating in case of higher thermal heating of stator winding. Different influencing input quantities from the instruments used for measurement in the test bench are studied and the uncertainty is analysed. While determining the efficiency of the machines the final measurement uncertainty of the test bench is examined and presented with "Guide to the Expression of Uncertainty in Measurement" (GUM) procedure. Besides the testing of the PMSM, this work, therefore, deals mainly with problems concerning the demagnetization of the PM during abnormal operating condition of PMSM using FEM simulation.
Reassessing the Evolutionary Importance of Inflammasomes
Creators: name: Miao, Edward A.
name: Maltez, Vivien I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Inflammasomes monitor the cytosol for microbial contamination or perturbation, and are thus predicted to provide potent defense against infection. However, the compendium of data from murine infection models suggests that inflammasomes merely delay the course of disease, allowing the host time to mount an adaptive response. Interpretations of such results are confounded by inflammasome evasion strategies of vertebrate-adapted pathogens. Conversely, environmental opportunistic pathogens have not evolved in the context of inflammasomes, and are therefore less likely to evade them. Indeed, opportunistic pathogens do not normally cause disease in wild type animals. Accordantly, the extreme virulence of two opportunistic bacterial pathogens, Burkholderia thailandensis and Chromobacterium violaceum, is fully counteracted by inflammasomes in murine models. This leads us to propose a new hypothesis: perhaps animals maintain inflammasomes over evolutionary time not to defend against vertebrate-adapted pathogens, but instead to counteract infection by a plethora of undiscovered opportunistic pathogens residing in the environment.
Regulatory T Cell Induction and Retention in the Lungs Drives Suppression of Detrimental Type 2 Th Cells During Pulmonary Cryptococcal Infection
Creators: name: Wiesner, Darin L.
name: Nielsen, Kirsten
name: Smith, Kyle D.
name: Kotov, Dmitri I.
name: Bohjanen, Paul R.
name: Nielsen, Judith N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Lethal disease caused by the fungus, Cryptococcus neoformans, is a consequence of the combined failure to control pulmonary fungal replication and immunopathology caused by induced type-2 helper T (Th2) cell responses in animal models. In order to gain incites into immune regulatory networks, we examined the role of regulatory T (Treg) cells in suppression of Th2 cells, using a mouse model of experimental cryptococcosis. Upon pulmonary infection with Cryptococcus, Treg cells accumulated in the lung parenchyma independently of priming in the draining lymph node. Using peptide-MHCII molecules to identify Cryptococcus-specific Treg cells combined with genetic fate-mapping, we noted that a majority of the Treg cells found in the lungs were induced during the infection. Additionally, we found that Treg cells utilized the transcription factor, Interferon Regulatory Factor 4 (IRF4), to dampen harmful Th2 cell responses, as well as mediate chemokine retention of Treg cells in the lungs. Taken together, induction and IRF4-dependent localization of Treg cells in the lungs allow Treg cells to suppress the deleterious effects of Th2 cells during cryptococcal infection.
Evolvulus hasslerianus Chodat, Bull. Herb. Boissier
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Solanales
Convolvulaceae
Evolvulus
Evolvulus hasslerianus

description: Evolvulus hasslerianus Chodat, Bull. Herb. Boissier, sér. 2(5): 685. 1905.
Herb.
 Vouchers: Alto Paraguay: Mereles & Degen 6362 (FCQ). Amambay: (Zuloaga et al. 2015). Concepción: Hassler 7836, type (F, G, K, MO, NH, NY, P, S).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Hierarchy of Steering Criteria Based on Moments for All Bipartite Quantum Systems
Creators: name: Kogias, Ioannis
name: Skrzypczyk, Paul
name: Cavalcanti, Daniel
name: Acin, Antonio
name: Adesso, Gerardo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Einstein-Podolsky-Rosen steering is a manifestation of quantum correlations exhibited by quantum systems, that allows for entanglement certification when one of the subsystems is not characterized. Detecting steerability of quantum states is essential to assess their suitability for quantum information protocols with partially trusted devices. We provide a hierarchy of sufficient conditions for the steerability of bipartite quantum states of any dimension, including continuous variable states. Previously known steering criteria are recovered as special cases of our approach. The proposed method allows us to derive optimal steering witnesses for arbitrary families of quantum states, and provides a systematic framework to analytically derive non-linear steering criteria. We discuss relevant examples and, in particular, provide an optimal steering witness for a lossy single-photon Bell state; the witness can be implemented just by linear optics and homodyne detection, and detects steering with a higher loss tolerance than any other known method. Our approach is readily applicable to multipartite steering detection and to the characterization of joint measurability.
description: 5+4 pages; Close to published version. Comments are welcome
Resolvin E1 Reverses Experimental Periodontitis and Dysbiosis
Creators: name: Lee, Chun-Teh
name: Paster, Bruce J.
name: Van Dyke, Thomas E.
name: Kantarci, Alpdogan
name: McCafferty, Jon
name: Chen, Tsute
name: Starr, Jacqueline R.
name: Teles, Ricardo
name: Brito, Luciana Carla Neves
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Periodontitis is a biofilm-induced inflammatory disease characterized by dysbiosis of the commensal periodontal microbiota. It is unclear how natural regulation of inflammation affects the periodontal biofilm. Promoters of active resolution of inflammation including Resolvin E1 (RvE1) effectively treat inflammatory periodontitis in animal models. The goals of this study were 1) to compare periodontal tissue gene expression in different clinical conditions, 2) to determine the impact of local inflammation on the composition of subgingival bacteria, and 3) to understand how inflammation impacts these changes. Two clinically-relevant experiments were performed in rats: prevention and treatment of ligature-induced periodontitis with RvE1 topical treatment. The gingival transcriptome was evaluated by RNA-seq sequencing of mRNA. The composition of the subgingival microbiota was characterized by 16S rDNA sequencing. Periodontitis was assessed by bone morphometric measurements and histomorphometry of block sections. H&E and, tartrate resistant acid phosphatase staining were used to characterize and quantify inflammatory changes. RvE1 treatment prevented bone loss in ligature induced periodontitis. Osteoclast density and inflammatory cell infiltration in the RvE1 groups were lower than those in the placebo group. RvE1 treatment reduced expression of inflammation-related genes returning the expression profile to one more similar to health. Treatment of established periodontitis with RvE1 reversed bone loss, reversed inflammatory gene expression and reduced osteoclast density. Assessment of the rat subgingival microbiota after RvE1 treatment revealed marked changes in both prevention and treatment experiments. The data suggest that modulation of local inflammation has a major role in shaping the composition of the subgingival microbiota.
Zebrafish IRF1, IRF3, and IRF7 Differentially Regulate IFNΦ1 and IFNΦ3 Expression through Assembly of Homo- or Heteroprotein Complexes
Creators: name: Feng, Hui
name: Li, Zhi
name: Xiong, Ya-Wei
name: Gui, Jian-Fang
name: Wu, Min
name: Zhang, Yi-Bing
name: Zhang, Qi-Min
name: Zhang, Jun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: In mammals, IFN regulatory factor (IRF)1, IRF3, and IRF7 are three critical transcription factors that are pivotal for cooperative regulation of the type I IFN response. In this study, we explored the relative contribution of zebrafish (Danio rerio) IRF1 (DrIRF1), IRF3 (DrIRF3), and IRF7 (DrIRF7) (DrIRF1/3/7) to zebrafish IFNΦ1 (DrIFNΦ1) and IFNΦ3 (DrIFNΦ3) (DrIFNΦ1/3) activation. Following spring viremia of carp virus infection, DrIFNΦ1/3 and DrIRF1/3/7 transcripts are significantly induced in zebrafish tissues, which correlates with the replication of spring viremia of carp virus. DrIRF1/3/7 selectively bind to the IRF-binding element/IFN-stimulated regulatory element sites of DrIFNΦ1/3 promoters, with the exception that DrIRF3 has no preference for two IRF-binding element/IFN-stimulated regulatory element motifs within the DrIFNΦ3 promoter. Consistently, DrIRF3 alone activates DrIFNΦ1, but not DrIFNΦ3; DrIRF7 predominantly stimulates DrIFNΦ3; and DrIRF1 has similar potential to DrIFNΦ1 and DrIFNΦ3. Strikingly, DrIRF3 facilitates the binding of DrIRF1 and DrIRF7 to both zebrafish IFN promoters, and so does DrIRF7 for the binding of DrIRF1, particularly to the DrIFNΦ3 promoter. These binding properties correlate with differential responses of DrIFNΦ1 and DrIFNΦ3 to the combinatory stimulation of DrIRF1/3/7, depending on their relative amounts. Similar to the dual roles of human IRF3 in regulating IRF7-activated IFNα genes, DrIRF3 exerts dual effects on DrIRF1-mediated DrIFNΦ3 gene expression: an inhibitory effect at lower concentrations and a synergistic effect at higher concentrations. These data provide evidence that fish and mammals have evolved a similar IRF-dependent regulatory mechanism fine-tuning IFN gene activation.
CEQAT-DGHS Ringversuchsprogramm für die Chemikaliensicherheit - Schlussfolgerungen
Creators: name: Lüth, Peter
name: Frost, Kirstin
name: Kurth, Lutz
name: Malow, Marcus
name: Schmidt, Martin
name: Michael-Schulz, Heike
name: Uhlig, Steffen
name: Zakel, Sabine
Publisher: name: Physikalisch-Technische Bundesanstalt (PTB)
Year: 2019
Subjects: Explosionsschutz
Ringvergleich
Chemikaliensicherheit
CEQAT-DGHS

description: Dies ist ein Beitrag für das 15. BAM-PTB-Kolloquium zur chemischen und physikalischen Sicherheitstechnik am 21. und 22. Mai 2019 bei der PTB in Braunschweig.
description: Die Ursachen für Chemikalienunfälle können vielfältig sein. Prävention beginnt bereits im Prüflabor, wenn Chemikalien auf ihre gefährlichen Eigenschaften getestet werden. Dazu sind Prüfmethoden entwickelt und veröffentlicht worden, die heute weltweit Anwendung finden. Auf die Validität der Prüfmethode und richtige Durchführung der Prüfung im Laboratorium müssen sich Sicherheitsfachkräfte, Transporteure oder Händler verlassen können. Anhand der in den letzten 10 Jahren im Rahmen des CEQAT-DGHS von BAM und PTB durchgeführten Ringversuche (RV) wird gezeigt, dass bei allen bisher untersuchten Prüfmethoden ein Verbesserungsbedarf besteht. Die RV müssen daher zunächst auf die Methodenverbesserung und -validierung abzielen und nicht auf Leistungstests. Das Labormanagement und die praktische Durchführung der Prüfung sind in vielen Laboratorien verbesserungsbedürftig. Der Begriff „Erfahrung der Prüfer“ ist kritisch zu sehen: Eine „lange Erfahrung mit vielen Prüfungen“ ist nicht unbedingt ein Garant für richtige Ergebnisse.
IL-10 Receptor Signaling Is Essential for T R 1 Cell Function In Vivo
Creators: name: Gagliani, Nicola
name: Krebs, Christian F.
name: Pelczar, Penelope
name: Mfarrej, Bechara
name: Geffken, Maria
name: Flavell, Richard A.
name: Steglich, Babett
name: Esplugues, Enric
name: Battaglia, Manuela
name: Huber, Francis
name: Brockmann, Leonie
name: Huber, Samuel
name: Wan, Yisong Y.
name: Kempski, Jan
name: Giannou, Anastasios D.
name: Herkel, Johannes
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Interleukin-10 (IL-10) is essential to maintain intestinal homeostasis. CD4+ T regulatory type 1 (TR1) cells produce large amounts of this cytokine and being therefore currently examined in clinical trials as T-cell therapy in patients with inflammatory bowel disease (IBD). However, factors and molecular signals sustaining TR1 cell regulatory activity still need to be identified in order to optimize the efficiency and to ensure the safety of these trials. We investigated the role of IL-10 signaling in mature TR1 cells in vivo.
High-spin structures of the near-spherical nuclei $^{91,92}$Zr
Creators: name: Srivastava, P. C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: In the present work, we have interpreted recently available experimental data for high-spin states of the near-spherical nuclei $^{91,92}$Zr, using the shell-model calculations within the full $f_{5/2}$, $p_{3/2}$, $p_{1/2}$, $g_{9/2}$ model space for protons and valence neutrons in $g_{9/2}$, $g_{7/2}$, $d_{5/2}$ orbits. We have employed a truncation for the neutrons due to huge matrix dimensions, by allowing one neutron excitation from $g_{9/2}$ orbital to $d_{5/2}$ and $g_{7/2}$ orbitals. Results are in good agreement with the available experimental data. Thus, theoretically, we have identified the structure of many high-spin states, which were tentatively assigned in the recent experimental work. The $^{91}$Zr $21/2^+$ isomer lies at low-energy region due to fully aligned spins of two $g_{9/2}$ protons and one $d_{5/2}$ neutron.
description: 14 pages, 5figures, Acta Physica Polonica B, Vol. 48 (2017)
Is Wave Mechanics consistent with Classical Logic?
Creators: name: Orefice, Adriano
name: Giovanelli, Raffaele
name: Ditto, Domenico
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Contrary to a wide-spread commonplace, an exact, ray-based treatment holding for any kind of monochromatic wave-like features (such as diffraction and interference) is provided by the structure itself of the Helmholtz equation. This observation allows to dispel - in apparent violation of the Uncertainty Principle - another commonplace, forbidding an exact, trajectory-based approach to Wave Mechanics.
description: 13 pages, 4 figures
NGC 6845: metallicity gradients and star formation in a complex compact group
Creators: name: Olave-Rojas, D.
name: Torres-Flores, S.
name: Carrasco, E. R.
name: de Oliveira, C. Mendes
name: de Mello, D. F.
name: Scarano, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We have obtained Gemini/GMOS spectra of 28 regions located across the interacting group NGC 6845, spanning from the inner regions of the four major galaxies (NGC 6845A, B, C, D) to the tidal tails of NGC 6845A. All regions in the tails are star-forming objects with ages younger than 10 Myr. We derived the gas-phase metallicity gradients across NGC 6845A and its two tails and we find that these are shallower than those for isolated galaxies. NGC 6845A has a gas-phase oxygen central metallicity of \mbox{12+log(O/H)$\sim$8.5} and a flat gas-phase metallicity gradient ($β$=0.002$\pm$0.004 dex kpc$^{-1}$) out to $\sim$4 $\times$ R$_{25}$ (to the end of the longest tidal tail). Considering the mass-metallicity relation, the central region of NGC 6845A displays a lower oxygen abundance than the expected for its mass. Taking into account this fact and considering the flat oxygen distribution measured along the eastern tidal tail, we suggest that an interaction event has produced a dilution in the central metallicity of this galaxy and the observed flattening in its metal distribution. We found that the star formation process along the eastern tidal structure has not been efficient enough to increase the oxygen abundances in this place, suggesting that this structure was formed from enriched material.
description: Accepted for publication in MNRAS, 18 pages, 11 figures, 6 tables
Ipomoea altoparanaensis O'Donell, Arq. Mus. Paranaense
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Solanales
Convolvulaceae
Ipomoea
Ipomoea altoparanaensis

description: Ipomoea altoparanaensis O’Donell, Arq. Mus. Paranaense 9: 210, t. 3. 1952.
Herb.
 Vouchers: Alto Paraná: Fiebrig 5812, type (GH, K, LIL, SI, US).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Quantum response theory for open systems and its application to Hall conductance
Creators: name: Shen, H. Z.
name: Qin, M.
name: Zhou, Y. H.
name: Shao, X. Q.
name: Yi, X. X.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum linear response theory considers only the response of a closed quantum system to a perturbation up to first order in the perturbation. This theory breaks down when the system subjects to environments and the response up to second order in perturbation is not negligible. In this paper, we develop a quantum nonlinear response theory for open systems. We first formulate this theory in terms of general susceptibility, then apply it to deriving the Hall conductance for the open system at finite temperature. Taking the two-band model as an example, we derive the Hall conductance for the two-band model. We calculate the Hall conductance for a two-dimensional ferromagnetic electron gas and a two-dimensional lattice model via different expressions for $d_α(\vec p), \ α=x,y,z$. The results show that the transition points of topological phase almost remain unchanged in the presence of environments.
description: 10 pages, 6 figures
Innate Immune Cell Recovery Is Positively Regulated by NLRP12 during Emergency Hematopoiesis
Creators: name: Sempowski, Gregory
name: Eitas, Timothy
name: Linz, Brandon M. L.
name: Kartchner, Laurel B.
name: Maile, Robert
name: Cairns, Bruce A.
name: Mendoza, April E.
name: Khoury, Amal L.
name: Neely, Crystal J.
name: Ting, Jenny P. Y.
name: Brickey, June
name: Truax, Agnieszka
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: With enhanced concerns of terrorist attacks, dual exposure to radiation and thermal combined injury (RCI) has become a real threat with devastating immunosuppression. NLRP12, a member of the NOD-like receptor family, is expressed in myeloid and bone marrow cells and has been implicated as a checkpoint regulator of inflammatory cytokines as well as an inflammasome activator. We show that NLRP12 has a profound impact on hematopoietic recovery during RCI by serving as a checkpoint of TNF signaling and preventing hematopoietic apoptosis. Using a mouse model of RCI, increased NLRP12 expression was detected in target tissues. Nlrp12−/− mice exhibited significantly greater mortality, inability to fight bacterial infection, heightened levels of pro-inflammatory cytokines, overt granulocyte/monocyte progenitor cell apoptosis and failure to reconstitute peripheral myeloid populations. Anti-TNF antibody administration improved peripheral immune recovery. These data suggest that NLRP12 is essential for survival after RCI by regulating myelopoiesis and immune reconstitution.
Towards Understanding User Preferences from User Tagging Behavior for Personalization
Creators: name: Nwana, Amandianeze O.
name: Chen, Tshuan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Multimedia (cs.MM)
subject: Human-Computer Interaction (cs.HC)
subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: Personalizing image tags is a relatively new and growing area of research, and in order to advance this research community, we must review and challenge the de-facto standard of defining tag importance. We believe that for greater progress to be made, we must go beyond tags that merely describe objects that are visually represented in the image, towards more user-centric and subjective notions such as emotion, sentiment, and preferences. We focus on the notion of user preferences and show that the order that users list tags on images is correlated to the order of preference over the tags that they provided for the image. While this observation is not completely surprising, to our knowledge, we are the first to explore this aspect of user tagging behavior systematically and report empirical results to support this observation. We argue that this observation can be exploited to help advance the image tagging (and related) communities. Our contributions include: 1.) conducting a user study demonstrating this observation, 2.) collecting a dataset with user tag preferences explicitly collected.
description: 6 pages
PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis
Creators: name: Panfil, Amanda R.
name: Webb, Lindsay M.
name: Guerau-De-Arellano, Mireia
name: Amici, Stephanie A.
name: Karkhanis, Vrajesh
name: Li, Chenglong
name: Savardekar, Himanshu
name: Peine, Kevin
name: Ainslie, Kristy M.
name: Li, Linsen
name: Bachelder, Eric M.
name: Baiocchi, Robert A.
name: Zhou, Wei
name: Green, Patrick L.
name: Jablonski, Kyle A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: In the autoimmune disease multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE), expansion of pathogenic, myelin-specific Th1 cell populations drives active disease; selectively targeting this process may be the basis for a new therapeutic approach. Previous studies have hinted at a role for protein arginine methylation in immune responses, including T cell–mediated autoimmunity and EAE. However, a conclusive role for the protein arginine methyltransferase (PRMT) enzymes that catalyze these reactions has been lacking. PRMT5 is the main PRMT responsible for symmetric dimethylation of arginine residues of histones and other proteins. PRMT5 drives embryonic development and cancer, but its role in T cells, if any, has not been investigated. In this article, we show that PRMT5 is an important modulator of CD4+ T cell expansion. PRMT5 was transiently upregulated during maximal proliferation of mouse and human memory Th cells. PRMT5 expression was regulated upstream by the NF-κB pathway, and it promoted IL-2 production and proliferation. Blocking PRMT5 with novel, highly selective small molecule PRMT5 inhibitors severely blunted memory Th expansion, with preferential suppression of Th1 cells over Th2 cells. In vivo, PRMT5 blockade efficiently suppressed recall T cell responses and reduced inflammation in delayed-type hypersensitivity and clinical disease in EAE mouse models. These data implicate PRMT5 in the regulation of adaptive memory Th cell responses and suggest that PRMT5 inhibitors may be a novel therapeutic approach for T cell–mediated inflammatory disease.
Staphylococcus aureus Protein A Disrupts Immunity Mediated by Long-Lived Plasma Cells
Creators: name: Kang, SunAh
name: Cunnion, Kenji M.
name: Spidale, Nicholas A.
name: Tisch, Roland
name: Richardson, Anthony R.
name: Keener, Amanda B.
name: Clarke, Stephen H.
name: Thurlow, Lance T.
name: Vilen, Barbara J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Infection with Staphylococcus aureus does not induce long-lived protective immunity for reasons that are not completely understood. Human and murine vaccine studies support a role for antibodies in protecting against recurring infections, but S. aureus modulates the B cell response through expression of Staphylococcal Protein A (SpA), a surface protein that drives polyclonal B cell expansion and induces cell death in the absence of co-stimulation. In this murine study, we show that SpA altered the fate of plasmablasts and plasma cells (PCs) by enhancing the short-lived extrafollicular response and reducing the pool of bone marrow (BM)-resident long-lived PCs (LLPCs). The absence of LLPCs was associated with a rapid decline in antigen-specific, class-switched antibody. In contrast, when previously inoculated mice were challenged with isogenic Δspa S. aureus, cells proliferated in the BM survival niches and sustained long-term antibody titers. The effects of SpA on PC fate were limited to the secondary response, as antibody levels and the formation of B cell memory occurred normally during the primary response in mice inoculated with either WT or Δspa S. aureus. Thus, failure to establish long-term protective antibody titers against S. aureus was not a consequence of diminished formation of B cell memory; instead, SpA reduced the proliferative capacity of PCs that entered the BM, diminishing the number of cells in the long-lived pool.
Solar small-scale dynamo and polarity of sunspot groups
Creators: name: Sokoloff, D.
name: Khlystova, A.
name: Abramenko, V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: In order to clarify a possible role of small-scale dynamo in formation of solar magnetic field, we suggest an observational test for small-scale dynamo action based on statistics of anti-Hale sunspot groups. As we have shown, according to theoretical expectations the small-scale dynamo action has to provide a population of sunspot groups which do not follow the Hale polarity law, and the density of such groups on the time-latitude diagram is expected to be independent on the phase of the solar cycle. Correspondingly, a percentage of the anti-Hale groups is expected to reach its maximum values during solar minima. For several solar cycles, we considered statistics of anti-Hale groups obtained by several scientific teams, including ours, to find that the percentage of anti-Hale groups becomes indeed maximal during a solar minimum. Our interpretation is that this fact may be explained by the small-scale dynamo action inside the solar convective zone.
description: 6 pages, 5 figures, accepted for publication in MNRAS