cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Impact of Inelastic Collisions with Hydrogen on NLTE Copper Abundances in Metal-Poor Stars
Creators: name: Xu, Xiaodong
name: Shi, Jianrong
name: Wang, Xiaofeng
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We investigate the non-local thermodynamic equilibrium (NLTE) analysis for \ion{Cu}{1} lines with the updated model atom that includes quantum-mechanical rate coefficients of Cu\,$+$\,H and Cu$^+$\,$+$\,H$^-$ inelastic collisions from the recent study of Belyaev et al. (2021). The influence of these data on NLTE abundance determinations has been performed for six metal-poor stars in a metallicity range of $-$2.59\,dex$\,\le$\,[Fe/H]\,$\le$\,$-$0.95\,dex. For \ion{Cu}{1} lines, the application of accurate atomic data leads to a decrease in the departure from LTE and lower copper abundances compared to that obtained with the Drawin's theoretical approximation. To verify our adopted copper atomic model, we also derived the LTE copper abundances of \ion{Cu}{2} lines for the sample stars. A consistent copper abundance from the \ion{Cu}{1} (NLTE) and \ion{Cu}{2} (LTE) lines has been obtained, which indicates the reliability of our copper atomic model. It is noted that the [Cu/Fe] ratios increase with increasing metallicity when $\sim$\,$-$2.0\,dex\,$<$\,[Fe/H]\,$<$\,$\sim$\,$-$1.0\,dex, favoring a secondary (metallicity-dependent) copper production.
Supratransmission in a Disordered Nonlinear Periodic Structure
Creators: name: Yousefzadeh, Behrooz
name: Phani, A. Srikantha
Publisher: name: arXiv
Year: 2015
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Dynamical Systems (math.DS)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We study the interaction among dispersion, nonlinearity, and disorder effects in the context of wave transmission through a discrete periodic structure, subjected to continuous harmonic excitation in its stop band. We consider a damped nonlinear periodic structure of finite length with disorder. Disorder is introduced throughout the structure by small changes in the stiffness parameters drawn from a uniform statistical distribution. Dispersion effects forbid wave transmission within the stop band of the linear periodic structure. However, nonlinearity leads to supratransmission phenomenon, by which enhanced wave transmission occurs within the stop band of the periodic structure when forced at an amplitude exceeding a certain threshold. The frequency components of the transmitted waves lie within the pass band of the linear structure, where disorder is known to cause Anderson localization. There is therefore a competition between dispersion, nonlinearity, and disorder in the context of supratransmission. We show that supratransmission persists in the presence of disorder. The influence of disorder decreases in general as the forcing frequency moves away from the pass band edge, reminiscent of dispersion effects subsuming disorder effects in linear periodic structures. We compute the dependence of the supratransmission force threshold on nonlinearity and strength of coupling between units. We observe that nonlinear forces are confined to the driven unit for weakly coupled systems. This observation, together with the truncation of higher-order nonlinear terms, permits us to develop closed-form expressions for the supratransmission force threshold. In sum, in the frequency range studied here, disorder does not influence the supratransmission force threshold in the ensemble-average sense, but it does reduce the average transmitted wave energy.
description: 29 pages, 25 figures
The Pianism of Ferruccio Busoni: A Critique of Selected Recordings and a Creative Re-Imagining Through New Performances
Creators: name: Chew, Aaron
Publisher: name: The Australian National University
Year: 2022

description: This exegesis investigates the pianism of Italian-German pianist, composer, educator, scholar, and conductor Ferruccio Busoni (1866-1924), and how it can reveal insightful and new pianistic interpretations via a study of a selection of reviews on Busoni's playing, memoirs written by his contemporaries and students, articles on piano playing by Busoni, an analysis of three works played by Busoni and an examination of my own performances of those three pieces. Five composers featured significantly in Busoni's huge repertoire: J. S. Bach, Beethoven, Chopin, Mozart, and Liszt. His playing style and interpretation of works by three of these composers will be analysed through case studies of Chopin's Preludes, Op. 28, Liszt's Hungarian Rhapsody No. 13, and Bach-Busoni's Chaconne in D Minor. In each of these case studies, I draw links between Busoni's performances and my execution of the same works, and how his musical aesthetics informed my overarching interpretation of the pieces. Finally, the exegesis proposes future avenues of research, such as a study of the pianism of Busoni's contemporaries, and ways that modern pianists can explore different interpretations in their own recitals.
title: Versorgungshintergrund und aktuelle Medikation bei entzündlich-rheumatischen Erkrankungen: Wie viel Information, Austausch und Mitsprache/Mitbestimmung wünschen sich Patienten im Arzt-Patienten-Gespräch?
Creators: name: Mattukat, Kerstin
name: Raberger, Katja
name: Böhm, Peter
name: Mau, Wilfried
name: Keyßer, Gernot
name: Schäfer, Christoph
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die Beteiligung von Patienten an therapeutischen Entscheidungen ist in nationalen und internationalen Leitlinien verankert, wird allerdings nicht von allen Patienten in gleichem Maße gewünscht. Die Berücksichtigung der Patientenwünsche bei anstehenden Entscheidungen kann[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Quantifying French Document Complexity
Creators: name: Primpied, Vincent
name: Beauchemin, David
name: Khoury, Richard
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computation and Language (cs.CL)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Measuring a document's complexity level is an open challenge, particularly when one is working on a diverse corpus of documents rather than comparing several documents on a similar topic or working on a language other than English. In this paper, we define a methodology to measure the complexity of French documents, using a new general and diversified corpus of texts, the "French Canadian complexity level corpus", and a wide range of metrics. We compare different learning algorithms to this task and contrast their performances and their observations on which characteristics of the texts are more significant to their complexity. Our results show that our methodology gives a general-purpose measurement of text complexity in French.
description: Accepted in CAIA 2022
Entropy in locally-de Sitter spacetimes
Creators: name: Araujo, A.
name: Pereira, J. G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: As quotient spaces, Minkowski and de Sitter are fundamental spacetimes in the sense that they are known "a priori", independently of Einstein equation. They represent different non-gravitational backgrounds for the construction of physical theories. If general relativity is constructed on a de Sitter spacetime, the underlying kinematics will no longer be ruled by Poincaré, but by the de Sitter group. In this case the definition of diffeomorphism changes, producing concomitant changes in the notions of energy and entropy. These changes are explicitly discussed for the case of the Schwarzschild solution, in which the black hole and the de Sitter horizons show up as a unique entangled system. Such entanglement, together with energy conservation, create a constraint between the black hole activity and the evolution of the de Sitter radius, providing a new scenario for the study of cosmology.
description: 11 pages. V2: presentation changes aiming at clarifying the text. Version accepted for publication in Int. J. Mod. Phys. D
Oral colostrum priming shortens hospitalization without changing the immunomicrobial milieu
Creators: name: Wynn,
name: Latuga,
name: Romano-Keeler,
name: McDonald,
name: Weitkamp,
name: Slaughter,
name: Azcarate-Peril,
name: Meng,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Oral colostrum priming (OCP) after birth in preterm infants is associated with improved weight gain and modification of the oral immuno-microbial environment. We hypothesized OCP would modify salivary immune peptides and the oral microbiota in preterm infants.
Episode 1: Pokémon – Pop Goes the Sneasel
Creators: name: Richards, Isabel
name: McCarthy, Ella
Publisher: name: Popsicule
Year: 2022
Subjects: Pokemon

description: I wanna be the very best … at science communication! Welcome to the first episode of Sci_Burst, spend an hour with us as we talk all things popularity, ecology and the gamification of science – Pokémon style. Sci_Burst – a podcast about science, popular culture and entertainment! We’re Isabel and Ella, two science communicators and Sci-fi nerds steering this spaceship into the multiverse of science fun! Our episodes cover everything from science in film and video games to comics, music, toys and beyond.
Deletion of toll-like receptor 4 ameliorates diabetic retinopathy in mice
Creators: name: Fu, Hongyu
name: Liu, Huiqiang
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Diabetic retinopathy is a common and specific microvascular complication of diabetes, which is also the leading cause of preventable blindness. Therefore, we aimed to find a promising therapeutic strategy for diabetic retinopathy. To investigate the role of toll-like receptor 4 (TLR4) in the diabetic retinopathy, we injected streptozotocin (STZ) into wild-type (wt) and TLR4 knock-out mice to induce diabetes. While STZ induced diabetes both in wt and TLR4−/− mice, deletion of TLR4 in diabetic mice significantly improved diabetic retinopathy compared to diabetic wt mice, as judged by the enhanced thickness of retinal tissue. Furthermore, TLR4-dependent NF-κB pathway, inflammatory cytokine release and the expressions of vascular endothelial growth factor (VEGF) and glial fibrillary acidic protein (GFAP), which were all remarkably stimulated in STZ-injected wt mice, were inhibited in STZ-injected TLR4−/− mice. TLR4 could serve as an independent target for treating diabetic retinopathy.
title: Die Screeningsprechstunde als wirksames und ressourcenschonendes Instrument zur frühen Diagnose und Therapie entzündlich-rheumatischer Erkrankungen: Daten aus der historischen Kohorte
Creators: name: Benesova, Karolina
name: Bender, Niko Kai
name: Lion, Vivienne Sonja Esther
name: Lorenz, Hanns-Martin
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die frühe Diagnosestellung und zeitnahe Einleitung einer spezifischen Therapie sind wesentliche prognostische Faktoren bei der Versorgung entzündlich-rheumatischer Erkrankungen. Der bundesweite Kapazitätsengpass mit Wartezeiten von mehreren Monaten bis zur ersten rheumatologischen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
title: BENEFIT Study: results of interim analysis of a Pan-European observational study to evaluate real-world effectiveness of SB4 following transition from originator etanercept (ETN) in patients with rheumatoid arthritis (RA) or axial sponyloarthritis (axSpA)
Creators: name: Krüger, Klaus
name: Zinke, Silke
name: Karberg, Kirsten
name: Freudensprung, Ulrich
name: Rezk, Mourad Farouk
name: Addison, Janet
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: SB4, a biosimilar to the reference ETN, received EU marketing authorisation in January 2016, based on the totality of evidence from pre-clinical and clinical Phase I and III studies that demonstrated similar efficacy, bioequivalence, and comparable safety and immunogenicity to ETN. There[for full text, please go to the a.m. URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Evolutionary game on networks with high clustering coefficient
Creators: name: Morita, Satoru
Publisher: name: arXiv
Year: 2015
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: This study investigates the influence of lattice structure in evolutionary games. The snowdrift games is considered in networks with high clustering coefficients, that use four different strategy-updating. Analytical conjectures using pair approximation were compared with the numerical results. Results indicate that general statements asserting that the lattice structure enhances cooperation are misleading.
description: 12 pages, 3 figures
भारतातील सामाजिक व राजकीय सुधारकांची महिला सक्षमीकरणातील योगदान...
Creators: name: प्रा.पेंडभाजे प्रियंका भाऊसाहेब
Publisher: name: Zenodo
Year: 2022
Subjects: समाजसुधारक, सक्षमीकरण, सामाजिक व राजकीय विकास, महिला.

description: सारांश जगातील कोणत्याही देशाला जलद चिंतन आणि सर्वसमावेशक विकास साधण्यासाठी पुरुषाप्रमाणे स्त्री ची ही आवश्यकता आहे. कारण सामाजिक व राजकीय विकासाची फळे स्त्री च्या योगदानाशिवाय कधीच पूर्ण होऊ शकत नाही, हे शास्त्रीय सैद्धांतिक सत्य आहे आणि या सत्याची सत्यता स्वामी विवेकानंदांच्या “There is no change for the welfare of the word unless conditions of women are improved. it is not possible for bird only with one wing” ‘या वाक्यातून होते .म्हणजेच या ठिकाणी स्त्रीचे राजकीय व समाजातील महत्त्व स्पष्ट होते. परंतु भारतीय समाज व्यवस्थेत पुरुषांना असणारे महत्त्वाचे स्थान पुरुषप्रधान समाजव्यवस्था महिलांना समाजात दिलेल्या निष्कृष्ट दर्जा यामुळे लोकसंख्येतील स्त्री हा मोठा घटक उपेक्षित राहिला आणि सर्वांगीण विकास प्रक्रियेपासून स्त्री ने देखील सामाजिक व राजकीय क्षेत्रात भरघोस प्रगती केली कारण प्राचीन काळापासून विविध समाजसुधारकांनी स्त्री च्या प्रगतीसाठी दिलेले योगदान फार महत्त्वाचे आहे
title: Rheuma-VOR: Eine Proof of Concept-Netzwerkstudie für die Verbesserung der rheumatologischen Versorgungsqualität durch koordinierte Kooperation
Creators: name: Dreher, Matthias
name: Schmidt, Reinhold E.
name: Assmann, Gunter
name: Hoeper, Kirsten
name: Triantafyllias, Konstantinos
name: Zeidler, Jan
name: Binder, Harald
name: Schwarting, Andreas
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die Rheumatoide Arthritis (RA), die Psoriasis Arthritis (PsA) und die Spondylarthritis (SpA) zählen zu den häufigsten rheumatologischen Erkrankungen. Bei allen drei Erkrankungsbildern scheint sich das sogenannte „window of opportunity“ [ref:1], [ref:2],[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Piper betleoides C. DC. Candollea 1925
Creators: name: Mukherjee, Prasanta Kumar
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Piperales
Piperaceae
Piper
Piper betleoides

description: 4. Piper betleoides C. DC. Candollea 2: 207. 1925
 Type:— INDIA: Darjeeling, J. S. Gamble 9645 (lectotype designated here CAL!; syntypes Sikkim, Rechilla, Unknown Collector s.n. CAL!, G00328837 image!, Tungyen, Brandis 1395 CAL!).
 Piper haridasanii Gajurel, Rethy & Kumar Piper species N. E. India 81. 2008 syn. nov.
 Type:— INDIA: Arunachal Pradesh: Durpang Reserve Forest, 31. 5. 1998 P. R. Gajurel 84 (holotype CAL!).
 Distribution:— INDIA: Arunachal Pradesh, Sikkim, West Bengal.
 Note:— The types mentioned for P. betleoides are from Darjeeling and Sikkim. Of these, J. S. Gamble 9645 at CAL is designated as the lectotype because it carries both the male and female twigs, conforming to the original description. Piper haridasanii Gajurel, Rethy & Kumar (2001: 293) was published without designation of a type. However, the holotype was designated by the authors in 2008 validating the name thereby. The two species are synonymized here as they are morphologically similar in every respect. This species is closely allied to P. boehmeriifolium (Miq.) Wall. ex C. DC. (869: 348), differing in the semi-coalescent fruits placed in grooves on the rachis.
description: Published as part of Mukherjee, Prasanta Kumar, 2018, Nomenclatural notes on Piper Linn. (Piperaceae) from India II, pp. 17-32 in Phytotaxa 338 (1) on pages 19-20, DOI: 10.11646/phytotaxa.338.1.2, http://zenodo.org/record/13719121
A Revolution in Science: the Eclipse Expeditions of 1919
Creators: name: Coles, Peter
Publisher: name: arXiv
Year: 2001
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The first direct experimental test of Einstein's theory of general relativity involved a pair of expeditions to measure the bending of light at a total solar eclipse that took place one hundred years ago, on 29 May 1919. So famous is this experiment, and so dramatic was the impact on Einstein himself, that history tends not to recognise the controversy that surrounded the results at the time. In this article, I discuss the experiment in its scientific and historical background context and explain why it was, and is, such an important episode in the development of modern physics.
description: 21 pages, 8 figures, revised and expanded to match version published in Contemporary Physics (2019)
Banks-Zaks fixed point analysis in momentum subtraction schemes
Creators: name: Gracey, J. A.
name: Simms, R. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We analyse the critical exponents relating to the quark mass anomalous dimension and beta-function at the Banks-Zaks fixed point in Quantum Chromodynamics (QCD) in a variety of representations for the quark in the momentum subtraction (MOM) schemes of Celmaster and Gonsalves. For a specific range of values of the number of quark flavours, estimates of the exponents appear to be scheme independent. Using the recent five loop modified minimal subtraction (MSbar) scheme quark mass anomalous dimension and estimates of the fixed point location we estimate the associated exponent as 0.263-0.268 for the SU(3) colour group and 12 flavours when the quarks are in the fundamental representation.
description: 33 latex pages, 25 tables, anc directory contains txt file with electronic version of renormalization group functions
Derivation and Validation of the Periodontal and Tooth Profile Classification System for Patient Stratification
Creators: name: Beck, James
name: Divaris, Kimon
name: Moss, Kevin L.
name: Offenbacher, Steven
name: Preisser, John S.
name: Morelli, Thiago
name: Wu, Di
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: BACKGROUND: The goal of this study is to use bioinformatics tools to explore identification and definition of distinct periodontal and tooth profile classes (PPCs/TPCs) among a cohort of individuals by using detailed clinical measures at the tooth level, including both periodontal measurements and tooth loss.

METHODS: Full-mouth clinical periodontal measurements (seven clinical parameters) from 6,793 individuals from the Dental Atherosclerosis Risk in Communities Study (DARIC) were used to identify PPC. A custom latent class analysis (LCA) procedure was developed to identify clinically distinct PPCs and TPCs. Three validation cohorts were used: NHANES (2009 to 2010 and 2011 to 2012) and the Piedmont Study population (7,785 individuals).

RESULTS: The LCA method identified seven distinct periodontal profile classes (PPCs A to G) and seven distinct tooth profile classes (TPCs A to G) ranging from health to severe periodontal disease status. The method enabled identification of classes with common clinical manifestations that are hidden under the current periodontal classification schemas. Class assignment was robust with small misclassification error in the presence of missing data. The PPC algorithm was applied and confirmed in three distinct cohorts.

CONCLUSIONS: The findings suggest PPC and TPC using LCA can provide robust periodontal clinical definitions that reflect disease patterns in the population at an individual and tooth level. These classifications can potentially be used for patient stratification and thus provide tools for integrating multiple datasets to assess risk for periodontitis progression and tooth loss in dental patients.
Uniqueness and order in sequential effect algebras
Creators: name: Gudder, S.
name: Greechie, R.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Rings and Algebras (math.RA)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics

description: A sequential effect algebra (SEA) is an effect algebra on which a sequential product is defined. We present examples of effect algebras that admit a unique, many and no sequential product. Some general theorems concerning unique sequential products are proved. We discuss sequentially ordered SEA's in which the order is completely determined by the sequential product. It is demonstrated that intervals in a sequential ordered SEA admit a sequential product.
title: Gesundheitsökonomische Analyse sowie Berechnung von direkten medizinischen und indirekten Kosten bei Patienten mit RA, PsA und AS im deutschen Praxisalltag – Evaluation der nicht-interventionellen Studie GO-NICE
Creators: name: Krüger, Klaus
name: Burmester, Gerd-Rüdiger
name: Wassenberg, Siegfried
name: Biermann, Valeria
name: Schöffski, Oliver
name: Thomas, Matthias
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Gesundheitsökonomische Analysen einer Rheuma-Therapie in der täglichen klinischen Praxis in Deutschland sind selten, werden aber von Kostenträgern zunehmend gefordert. Ziel war es, gesundheitsökonomische Parameter zu analysieren und Kosten aus gesellschaftlicher und GKV-Perspektive[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
title: Analysis of potential differential adipokine and IL-17 effects on synovial fibroblasts from different rheumatic disease backgrounds
Creators: name: Frommer, Klaus
name: Rehart, Stefan
name: Sauerbier, Michael
name: Müller-Ladner, Ulf
name: Neumann, Elena
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are similar but yet distinct diseases. RA and PsA synovial fibroblasts (SF), known key effector cells in the pathophysiology of chronic inflammatory arthritis, respond to various stimuli including adipokines and cytokines. We hypothesized[for full text, please go to the a.m. URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Molecular gas as the driver of fundamental galactic relations
Creators: name: Bothwell, M. S.
name: Maiolino, R.
name: Peng, Y.
name: Cicone, C.
name: Griffith, H.
name: Wagg, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: There has been much recent work dedicated to exploring secondary correlations in the mass-metallicity relation, with significant dependence on both the star formation rate and HI content being demonstrated. Previously, a paucity of molecular gas data (combined with sample selection bias) hampered the investigation of any such relation with molecular gas content. In this work, we assemble a sample of 221 galaxies from a variety of surveys in the redshift range 0 < z < 2, to explore the connection between molecular gas content and metallicity. We explore the effect of gas mass on the mass-metallicity relation, finding that the offset from the relation is negatively correlated against both molecular and total gas mass. We then employ a principle component analysis technique to explore secondary dependences in the mass-metallicity relation, finding that the secondary dependence with gas mass is significantly stronger than with star formation rate, and as such the underlying `Fundamental Metallicity Relation' is between stellar mass, metallicity, and gas mass. In particular, the metallicity dependence on SFR is simply a byproduct of the dependence on the molecular gas content, via the Schmidt-Kennicutt relation. Finally, we note that our principle component analysis finds essentially no connection between gas-phase metallicity and the efficiency of star formation.
description: 20 pages, 10 figures. Replacement version accepted for publication in MNRAS
Piper curtistipes C. DC. Candollea
Creators: name: Mukherjee, Prasanta Kumar
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Piperales
Piperaceae
Piper
Piper curtistipes

description: 5. Piper curtistipes C. DC. Candollea 2: 213.1925.
 Type:— INDIA: Sikkim, King’s collector 2271 (holotype CAL!).
 P. mannii C. DC. Candollea 2: 204. 1925 pro parte syn. nov.
 Type:— INDIA: Manipur, Siogha (Sirohe?)  Gamble 2577 β  (lectotype designated here CAL!).
 Distribution:— INDIA: Sikkim, Meghalaya; Bhutan.
 Note:— This species seems similar in description to Piper caninum Bl. var. lanceolatum Hook. f. (1886: 82). Long (1984: 350) wrongly considered this as a synonym of Piper khasianum C. DC. (1869: 349), from which it differs in possessing pedicellate fruits. Piper curtistipes forma b C. DC. (1925: 213) cannot be considered as a legitimate name and therefore it cannot have a type; in spite of citation of “Khasia, Masododon, 300m  C. B. Clarke 42931 β  CAL!. (number was misquoted by C. DC. as  4231 β )”. This species differs from P. muneyporense C. DC. (1925: 213) in its glabrous rachis instead of being puberulous in the latter.
description: Published as part of Mukherjee, Prasanta Kumar, 2018, Nomenclatural notes on Piper Linn. (Piperaceae) from India II, pp. 17-32 in Phytotaxa 338 (1) on page 20, DOI: 10.11646/phytotaxa.338.1.2, http://zenodo.org/record/13719121
Non-Surgical Therapy Reduces Presence of JP2 Clone in Localized Aggressive Periodontitis
Creators: name: Huang, Hong
name: Aukhil, Ikramuddin
name: Burgess, Danielle K.
name: Shaddox, Luciana M.
name: Kompotiati, Theodora
name: Harrison, Peter
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Previous studies have provided substantial evidence on the association of Aggregatibacter actinomycetemcomitans (Aa), and its highly leukotoxic JP2 genotype, with localized aggressive periodontitis (LAP). The present study aims to evaluate the presence of JP2 in LAP individuals following periodontal treatment.
title: Targeting fibroblast-like synoviocytes in rheumatoid arthritis by JAK inhibition with peficitinib
Creators: name: Diller, Magnus
name: Hülser, Marie-Lisa
name: Hasseli, Rebecca
name: Rehart, Stefan
name: Müller-Ladner, Ulf
name: Neumann, Elena
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: The Janus kinase inhibitors (JAKi) tofacitinib and baricitinib have extended the opportunities for the therapy of rheumatoid arthritis (RA). Meanwhile, other JAKi have been developed completed successfully phase II trials. Peficitinib, a pan-JAKi and filgotinib, a JAK-1 inhibitor are currently[for full text, please go to the a.m. URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Functional intimacy: Needing—But not wanting—The touch of a stranger.
Creators: name: Schroeder, Juliana
name: Gray, Kurt
name: Schein, Chelsea
name: Fishbach, Ayelet
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Intimacy is often motivated by love, but sometimes it is merely functional. For example, disrobing and being touched at an airport security check serves the goal of catching a flight, not building a relationship. We propose that this functional intimacy induces discomfort, making people prefer greater social distance from their interaction partner. Supporting this prediction, participants who considered (Experiments 1 and 2) or experienced (Experiment 3) more physically intimate medical procedures preferred a health provider who is less social. Increased psychological intimacy also led people to prefer social distance from cleaning and health providers (Experiments 4-5), a preference revealed by nonverbal behavior (e.g., turning away and looking away, Experiments 6-7). These patterns of distancing are unique to functional (vs. romantic) intimacy (Experiment 7). Although creating social distance may be an effective strategy for coping with functional intimacy, it may have costs for service providers. (PsycINFO Database Record
Protoplanetary Disk Evolution: Singles vs. Binaries
Creators: name: Daemgen, Sebastian
name: Jayawardhana, Ray
name: Petr-Gotzens, Monika G.
name: Meyer, Elliot
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Based on a large number of observations carried out in the last decade it appears that the fraction of stars with protoplanetary disks declines steadily between ~1 Myr and ~10 Myr. We do, however, know that the multiplicity fraction of star-forming regions can be as high as >50% and that multiples have reduced disk lifetimes on average. As a consequence, the observed roughly exponential disk decay can be fully attributed neither to single nor binary stars and its functional form may need revision. Observational evidence for a non-exponential decay has been provided by Kraus et al. (2012), who statistically correct previous disk frequency measurements for the presence of binaries and find agreement with models that feature a constantly high disk fraction up to ~3 Myr, followed by a rapid ($\lesssim$2 Myr) decline. We present results from our high angular resolution observational program to study the fraction of protoplanetary disks of single and binary stars separately. We find that disk evolution timescales of stars bound in close binaries (<100 AU) are significantly reduced compared to wider binaries. The frequencies of accretors among single stars and wide binaries appear indistinguishable, and are found to be lower than predicted from planet forming disk models governed by viscous evolution and photoevaporation.
description: 4 pages, 1 figure. To appear in the proceedings of IAU Symposium 314 "Young Stars & Planets Near the Sun", Atlanta, GA, May 11-15, 2015
स्त्री चळवळीचा समाजशास्त्रीय अभ्यास
Creators: name: प्रा. कन्नाडे एम. के.
Publisher: name: Zenodo
Year: 2022

description: कोणत्याही समाजात निर्माण झालेल्या सामाजिक समस्यांचे निर्मुलन करण्यासाठी मोठया समुदायाद्वारा केला जाणारा सामुहिक प्रयत्न म्हणजे सामाजिक चळवळ होय. सामाजिक चळवळ ही समाज वा संस्कृतीत नवीन परिवर्तन करण्यासाठी किंवा त्या परिवर्तनाला विरोध करण्यासाठी निर्माण होते.
Supplementary Data File: from Rapid brain development and reduced neuromodulator titres correlate with host shifts in Rhagoletis pomonella
Creators: name: Kharva, Hinal
name: Feder, Jeffrey L.
name: Hahn, Daniel A.
name: Olsson, Shannon B.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: This file contains extended methods, figures s1-s7, tables s1-s12 and movie 1-7
A sensitive high performance liquid chromatography assay for the quantification of doxorubicin associated with DNA in tumor and tissues
Creators: name: White, Taylor F.
name: Lucas, Andrew T.
name: O'Neal, Sara K.
name: Santos, Charlene M.
name: Zamboni, William C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: A HPLC method was validated to quantify doxorubicin associated to DNA from tissue.Successfully applied to an in vivo mouse-based pharmacokinetic study.Important tool for future studies evaluating intracellular pharmacokinetics.Doxorubicin, a widely used anticancer agent, exhibits antitumor activity against a wide variety of malignancies. The drug exerts its cytotoxic effects by binding to and intercalating within the DNA of tumor and tissue cells. However, current assays are unable to accurately determine the concentration of the intracellular active form of doxorubicin. Thus, the development of a sample processing method and a high-performance liquid chromatography (HPLC) methodology was performed in order to quantify doxorubicin that is associated with DNA in tumors and tissues, which provided an intracellular cytotoxic measure of doxorubicin exposure after administration of small molecule and nanoparticle formulations of doxorubicin. The assay uses daunorubicin as an internal standard; liquid–liquid phase extraction to isolate drug associated with DNA; a Shimadzu HPLC with fluorescence detection equipped with a Phenomenex Luna C18 (2 μm, 2.0 × 100 mm) analytical column and a gradient mobile phase of 0.1% formic acid in water or acetonitrile for separation and quantification. The assay has a lower limit of detection (LLOQ) of 10 ng/mL and is shown to be linear up to 3000 ng/mL. The intra- and inter-day precision of the assay expressed as a coefficient of variation (CV%) ranged from 4.01 to 8.81%. Furthermore, the suitability of this assay for measuring doxorubicin associated with DNA in vivo was demonstrated by using it to quantify the doxorubicin concentration within tumor samples from SKOV3 and HEC1A mice obtained 72 h after administration of PEGylated liposomal doxorubicin (Doxil®; PLD) at 6 mg/kg IV x 1. This HPLC assay allows for sensitive intracellular quantification of doxorubicin and will be an important tool for future studies evaluating intracellular pharmacokinetics of doxorubicin and various nanoparticle formulations of doxorubicin.
Co-culture of Hepatocytes and Kupffer Cells as an  In Vitro  Model of Inflammation and Drug-Induced Hepatotoxicity
Creators: name: Rose, Kelly A.
name: Andersen, Melvin E.
name: Holman, Natalie S.
name: Lecluyse, Edward L.
name: Green, Angela M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Immune-mediated drug-induced hepatotoxicity is often unrecognized as a potential mode of action due to the lack of appropriate in vitro models. We have established an in vitro rat donor-matched hepatocyte and Kupffer cell co-culture (HKCC) model to study immune-related responses to drug exposure. Optimal cell culture conditions were identified for the maintenance of co-cultures based on cell longevity, monolayer integrity, and cytokine response after lipopolysaccharide (LPS) exposure. Hepatocyte monocultures and HKCCs were then used to test a subset of compounds associated with hepatotoxic effects with or without LPS. Cytokine levels and metabolic activity (cytochrome P450 3A [Cyp3A]) were measured after a 48-h exposure to monitor endotoxin-induced changes in acute phase and functional end points. LPS-activated HKCCs, but not hepatocyte monocultures, treated with trovafloxacin or acetaminophen, compounds associated with immune-mediated hepatotoxicity, showed LPS-dependent decreases in interleukin-6 production with concomitant increases in Cyp3A activity. Differential endotoxinand model-dependent alterations were observed in cytokine profiles and Cyp3A activity levels that corresponded to specific compounds. These results indicate the utility of the HKCC model system to discern compound-specific effects that may lead to enhanced or mitigate hepatocellular injury due to innate or adaptive immune responses.
Deliverable 3.7 First implementation and data: North of Svalbard
Creators: name: Johannessen, Truls
name: Roden, Nicholas
name: Olsen, Are
name: de Lange, Tor
name: Sodemann, Harald
name: Touzeau, Alexandra
name: Smedsrud, Lars H.
name: Sørensen, Mathilde B.
name: Jeddi, Zeinab
name: Beszczynska-Möller, Agnieszka
name: Walczowski, Waldemar
name: Nizetto, Luca
name: Allan, Ian
name: Renner, Angelica
name: Soltwedel, Thomas
name: Walte, Anja
name: Rogge, Andreas
name: Nilsen, Frank
name: Voss, Peter H.
name: Herbaut, Christophe
name: Houssais, Marie-Noëlle
name: Sagen, Hanne
Publisher: name: Zenodo
Year: 2019

description: The main goal of Task 3.2 is to deliver in situ ocean and sea ice observations collected during two INTAROS field seasons and to provide recommendations for future implementation of the moored observing system north of Svalbard that can be applied to define a roadmap for observing future changes in the Arctic. The aim is to make comprehensive observations of the ongoing climate and environmental change that can be also applied as a validation tool for conceptual and three-dimensional modelling. This report describes the first implementation and operational use of the observing systems. Data delivery and report on results of the observing systems North Svalbard. The first implementation was deployed successfully in August 2018 using the Coast Guard icebreaker KV Svalbard and retrieved with KV Svalbard in August/September and with the research icebreaker RV Kronprins Håkon in September and November 2019. All recovered instrument and sensor provided full data return therefore a full annual cycle of multidisciplinary data was obtained that can be employed to address the following goals: −Document the performance of instruments and systems selected/integrated for measurements of key ocean physical variables on INTAROS moorings, including temperature, salinity and ocean currents −Document the performance of instruments and sensors selected/integrated for measurements of key biogeochemical variables including dissolved oxygen, nutrients and carbonate system parameters on the multidisciplinary BGC11mooring −Document the performance of novel instruments selected for sea ice measurements on the moorings along the INTAROS (22°E) and A-TWAIN (31°E) lines north of Svalbard −Document the performance of novel combination of ADCP with echo sounder selected for ocean currents and zooplankton/small fish abundance measurements −Document the performance and the state of technical development for a moored multisensor Octopus system for biological measurements, including an Underwater Vision Profiler, nutrient sensor and chlorophyll-a and CDOM fluorometer −Document the performance and technical development for microplastic samplers −Document the performance of technologies and deployment methodology for the sensors mounted at the seafloor, including Ocean Bottom Pressure sensors and Ocean Bottom Seismometers
Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases
Creators: name: Sadgrove, Matthew P.
name: Fu, Jing
name: Jay, Michael
name: Pacyniak, Erik
name: Marson, Lesley
name: Leed, Marina G.D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The penta-ethyl ester prodrug of the chelating agent diethylene triamine pentaacetic acid (DTPA) referred to as C2E5, is being developed as an orally bioavailable radionuclide decorporation agent. The predicted human efficacy obtained in these experimental animals is confounded by interspecies variations of metabolism. Therefore, in the present study, carboxylesterase-mediated metabolism of [14C]-C2E5 was compared in the S9 intestinal and hepatic fractions of human, dog and rat and their respective plasma. Intestinal hydrolysis of C2E5, resulting in the formation of the tetraethyl ester of DTPA (C2E4), was only detected in human and rat. The primary metabolite in human and dog hepatic fractions was C2E4 whereas the predominant species identified in rat hepatic fractions was the triethyl ester (C2E3). Hepatic hydrolysis of C2E5 causes the formation of C2E4 in human, dog and rat and C2E3 in rat only. Minimal C2E5 hydrolysis was observed in human and dog plasma whereas in rat plasma C2E5 converted to C2E3 rapidly, followed by slower further metabolism. Both recombinant CES1 and CES2 play roles in C2E5 metabolism. Together, these data suggest that dogs may be the most appropriate species for predicting human C2E5 metabolism whereas rats might be useful for clarifying the potential toxicity of C2E5 metabolites.
Piper japvonum C. DC. Candollea
Creators: name: Mukherjee, Prasanta Kumar
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Piperales
Piperaceae
Piper
Piper japvonum

description: 8. Piper japvonum C. DC. Candollea 2: 200. 1925.
 Type:— INDIA: Manipur, Japvo, G. Watt 6325 (holotype CAL!; isotypes E00313753 image!, K image 000794453!).
 Distribution:— INDIA: Manipur.
 Note: —Casimir de Candolle cited the specimen at CAL as the type. There he attached a scrap with a note in 1911 stating “not to be published because of spike being loose”. This specimen is without any spike at present, which was presumably lost during preservation. Fortunately, the duplicates at E and K (stored as P. suipigua Buch. -Ham. ex D. Don (1825: 20) have the reproductive structures. D. G. Long (1984) incorrectly considered this species to be similar to P. suipigua. Piper japvonum in general appearance is blackish, has ovate to caudate leaves, fruiting spikes less than half the length of the lamina, rachis hirsute, fruits packed, ovate, stigmas 4. Piper suipigua on drying appears pale green or lighter, has elliptic or elliptic-lanceolate leaves, fruiting spikes shorter or longer than lamina, rachis densely tomentose, fruits loosely packed, fruits ovoid and 3 stigmas.
description: Published as part of Mukherjee, Prasanta Kumar, 2018, Nomenclatural notes on Piper Linn. (Piperaceae) from India II, pp. 17-32 in Phytotaxa 338 (1) on page 21, DOI: 10.11646/phytotaxa.338.1.2, http://zenodo.org/record/13719121
Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury
Creators: name: Brouwer, Kim L.R.
name: Siler, Scott Q.
name: Guo, Cen
name: Woodhead, Jeffrey L.
name: Howell, Brett A.
name: Watkins, Paul B.
name: Yang, Kyunghee
name: St Claire, Robert L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Sandwich-cultured hepatocytes (SCH) are metabolically competent and have proper localization of basolateral and canalicular transporters with functional bile networks. Therefore, this cellular model is a unique tool that can be used to estimate biliary excretion of compounds. SCH have been used widely to assess hepatobiliary disposition of endogenous and exogenous compounds and metabolites. Mechanistic modeling based on SCH data enables estimation of metabolic and transporter-mediated clearances, which can be employed to construct physiologically-based pharmacokinetic models for prediction of drug disposition and drug-drug interactions in humans. In addition to pharmacokinetic studies, SCH also have been employed to study cytotoxicity and perturbation of biological processes by drugs and hepatically-generated metabolites. Human SCH can provide mechanistic insights underlying clinical drug-induced liver injury (DILI). In addition, data generated in SCH can be integrated into systems pharmacology models to predict potential DILI in humans. In this review, applications of SCH in studying hepatobiliary drug disposition and bile acid-mediated DILI are discussed. An example is presented to show how data generated in the SCH model was used to establish a quantitative relationship between intracellular bile acids and cytotoxicity, and how this information was incorporated into a systems pharmacology model for DILI prediction.
title: TGFb bound to GARP promotes acetylation-mediated FOXP3 protein stabilization
Creators: name: Lehmkuhl, Peter
name: Zapp, Benedikt
name: Schulze-Koops, Hendrik
name: Skapenko, Alla
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Regulatory T cells (Tregs) play a critical role in maintaining homeostasis and limiting autoimmunity. The transcription factor Forkhead box P3 (FOXP3) has been identified as the key regulator of Treg function and development. Its activity and stability are tightly regulated by acetylation[for full text, please go to the a.m. URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
MPEC 2023-L15 : 2023 KM5
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Electroweak phase transition and some related phenomena- a brief review
Creators: name: Ghosh, Buddhadeb
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this article, we review Electroweak Phase transition and some related phenomena.
description: 20 pages, 8 figures, invited article for Pramana, 18 LaTex pages in the revised version, 13 more references added, typos corrected, a label in fig.2 corrected, sections 2 and 3 elaborated