cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Manning, L. (2024). The role of standards and certification in delivering safe, sustainable and socially-responsible agri-food supply chains. Manning L. (ed.), Improving standards and certification in agri-food supply chains: Ensuring safety, sustainability and social responsibility Burleigh Dodds Science Publishing, Cambridge, UK, 2024, (ISBN: 978 1 80146 451 2;
Creators: name: Manning, Louise
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 300699
subject: Food sciences not elsewhere classified

description: The evolution of standards and certification in agri-food chains has taken place over nearly 40 years. The dynamics that led to this form of private governance have also change over time. Contemporary issues such as climate change, biodiversity loss, and seeking to develop a food system that is resilient and sustainable has led to the emergence of new principles, practices and outcomes that the agri-food supply chain must deliver. This chapter reflects on these trends and the themes that run through the book to consider how we deliver safe, sustainable and socially responsible supply chains, now and into the future.
Model fusion with physics-guided machine learning
Creators: name: Pawar, Suraj
name: San, Omer
name: Nair, Aditya
name: Rasheed, Adil
name: Kvamsdal, Trond
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The unprecedented amount of data generated from experiments, field observations, and large-scale numerical simulations at a wide range of spatio-temporal scales have enabled the rapid advancement of data-driven and especially deep learning models in the field of fluid mechanics. Although these methods are proven successful for many applications, there is a grand challenge of improving their generalizability. This is particularly essential when data-driven models are employed within outer-loop applications like optimization. In this work, we put forth a physics-guided machine learning (PGML) framework that leverages the interpretable physics-based model with a deep learning model. The PGML framework is capable of enhancing the generalizability of data-driven models and effectively protect against or inform about the inaccurate predictions resulting from extrapolation. We apply the PGML framework as a novel model fusion approach combining the physics-based Galerkin projection model and long-short term memory (LSTM) network for parametric model order reduction of fluid flows. We demonstrate the improved generalizability of the PGML framework against a purely data-driven approach through the injection of physics features into intermediate LSTM layers. Our quantitative analysis shows that the overall model uncertainty can be reduced through the PGML approach especially for test data coming from a distribution different than the training data. Moreover, we demonstrate that our approach can be used as an inverse diagnostic tool providing a confidence score associated with models and observations. The proposed framework also allows for multi-fidelity computing by making use of low-fidelity models in the online deployment of quantified data-driven models.
Supplemental material - Enhanced osteogenesis and angiogenesis of biphasic calcium phosphate scaffold by synergistic effect of silk fibroin coating and zinc doping
Creators: name: Lu, Teliang
name: Ma, Ning
name: He, Fupo
name: Liang, Yongyi
name: Ye, Jiandong
Publisher: name: SAGE Journals
Year: 2022
Subjects: Materials Engineering not elsewhere classified

description: Supplemental material for Enhanced osteogenesis and angiogenesis of biphasic calcium phosphate scaffold by synergistic effect of silk fibroin coating and zinc doping by Teliang Lu, Ning Ma, Fupo He, Yongyi Liang, and Jiandong Ye in Journal of Biomaterials Applications
Additional file 2 of Exploring trial publication and research waste in COVID-19 randomised trials of hydroxychloroquine, corticosteroids, and vitamin D: a meta-epidemiological cohort study
Creators: name: Fincham, Lisa
name: Hohlfeld, Ameer
name: Clarke, Mike
name: Kredo, Tamara
name: McCaul, Michael
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2
sj-docx-1-cpc-10.1177_10556656221123917 - Supplemental material for Modified Medial Incision Small Double-Opposing Z-Plasty for Treating Veau Type I Cleft Palate: Is the Early Result Reproducible?
Creators: name: Denadai, Rafael
name: Seo, Hyung Joon
name: Go Pascasio, Dax Carlo
name: Sato, Nobuhiro
name: Murali, Srinisha
name: Lo, Chi-Chin
name: Chou, Pang-Yung
name: Lo, Lun-Jou
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-cpc-10.1177_10556656221123917 for Modified Medial Incision Small Double-Opposing Z-Plasty for Treating Veau Type I Cleft Palate: Is the Early Result Reproducible? by Rafael Denadai, Hyung Joon Seo, Dax Carlo Go Pascasio, Nobuhiro Sato, Srinisha Murali, Chi-Chin Lo, Pang-Yung Chou and Lun-Jou Lo in The Cleft Palate-Craniofacial Journal
Supplemental Material - Role of adding carbon nanotubes in the electric and electromagnetic shielding behaviors of three different types of graphene in hybrid nanocomposites
Creators: name: dos Anjos, Erick GR
name: Moura, Nayara K
name: Antonelli, Eduardo
name: Baldan, Mauricio R
name: Gomes, Newton AS
name: Braga, Natália F
name: Santos, Adelina P
name: Rezende, Mirabel C
name: Pessan, Luiz A
name: Passador, Fabio R
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental Material for Role of adding carbon nanotubes in the electric and electromagnetic shielding behaviors of three different types of graphene in hybrid nanocomposites by Erick GR dos Anjos, Nayara Kd Moura, Eduardo Antonelli, Mauricio R Baldan, Newton AS Gomes, Natália F Braga, Adelina P Santos, Mirabel C Rezende, Luiz A Pessan and Fabio R Passador in Journal of Thermoplastic Composite Materials
sj-docx-1-sim-10.1177_00375497221120018 – Supplemental material for A simulation approach for COVID-19 pandemic assessment based on vaccine logistics, SARS-CoV-2 variants, and spread rate
Creators: name: Erkayman, Burak
name: Ak, Ferhat
name: Çodur, Sadrettin
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies
subject: Science Policy

description: Supplemental material, sj-docx-1-sim-10.1177_00375497221120018 for A simulation approach for COVID-19 pandemic assessment based on vaccine logistics, SARS-CoV-2 variants, and spread rate by Burak Erkayman, Ferhat Ak and Sadrettin Çodur in SIMULATION
Dispersive Estimates for Nonlinear Schrödinger Equations with External Potentials
Creators: name: Dietze, Charlotte
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 35Q55

description: We consider the long time dynamics of nonlinear Schrödinger equations with an external potential. More precisely, we look at Hartree type equations in three or higher dimensions with small initial data. We prove an optimal decay estimate, which is comparable to the decay of free solutions. Our proof relies on good control on a high Sobolev norm of the solution to estimate the terms in Duhamel's formula.
description: 31 pages, 1 figure
Student created video content for assessment, experiential learning, and service
Creators: name: Graul, Ben
name: Rollins, Matthew L.
name: Powers, Nathan
name: Della Corte, Dennis
Publisher: name: arXiv
Year: 2020
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: This paper outlines the feasibility of replacing a midterm assessment with a student-created digital media project. We examine the benefits of a peer review process for student-created pedagogy, the effectiveness of the student-generated digital media, and self-evaluations as a replacement for accepted forms of assessment in terms of: learning, assessment, and service provided. The outlined project also facilitates the creation of a video bank easily accessible for professors and students alike in introductory physics courses using the OpenStax College Physics textbook.1 We conclude that this non-traditional teaching and assessment model is both effective and timely as more college courses are being taught digitally and/or asynchronously.
description: 9 pages manuscript, 1 figure, 1 table, 10 pages supplementary information
Prevalence and risk factors of antibiotic resistance for urinary tract infections in patients presenting to a Belgian tertiary care emergency department: testing the national guidelines against the local setting
Creators: name: Schmitz, L.
name: Yepiskoposyan, L.
name: Bouteille, A.
name: Wybo, I.
name: Allard, S. D.
name: Pauwels, S.
name: Hubloue, I.
name: Van Honacker, E.
name: Van Laethem, J.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Urinary tract infections (UTIs) are an important cause of empiric antibiotic (over)treatment at the emergency department (ED). To enhance empiric antibiotic choices, mapping the national and local microbiology and antimicrobial resistance (AMR) patterns is crucial. This study aims to examine resistance patterns at a Brussels ED and to identify risk factors for AMR to evaluate current treatment guidelines and help combat AMR. Adult patients undergoing urinalysis at the ED of a Brussels tertiary care hospital with positive urine cultures were included. Descriptive microbiological mapping of UTI or asymptomatic bacteriuria (ASB) micro-organisms was performed. Potential risk factors of antibiotic resistance in Gram-negative bacteria were assessed by using logistic regression analysis. Out of 96 patients with Gram-negative bacteria in urinary culture, the predominant uropathogen was Escherichia coli (58.3%), with 8.6% being extended spectrum beta-lactamase (ESBL)-producing strains. Overall, fosfomycin (29.2%) and nitrofurantoin (28.6%) showed the highest resistance rates. Ceftriaxone revealed lower resistance rates (13.1%) compared to ciprofloxacin (17.0%) and cefuroxime (18.4%). Temocillin exhibited the lowest resistance rate (8.2%) especially against ESBLs (0%). Ciprofloxacin resistance increased with age (OR 1.05 [1.01–1.10]) and recurrent UTIs (OR 4.79 [1.18–19.42]). Male gender was associated with higher odds of temocillin resistance (OR 5.79 [1.18–28.34]). In the studied Belgian ED setting, ceftriaxone seems slightly safer than ciprofloxacin, especially for recurrent UTI patients. However, overall, and especially in patients at risk for ESBL-producing bacteria, temocillin would be an even better choice in our setting. National microbiological data should be reviewed to support recommending temocillin as a first-line antibiotic in patients presenting with upper UTI.
sj-docx-2-jre-10.1177_15562646221118127 - Supplemental material for Equitable Design and Use of Digital Surveillance Technologies During COVID-19: Norms and Concerns
Creators: name: Pratt, Bridget
name: Parker, Michael
name: Bull, Susan
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, sj-docx-2-jre-10.1177_15562646221118127 for Equitable Design and Use of Digital Surveillance Technologies During COVID-19: Norms and Concerns by Bridget Pratt, Michael Parker and Susan Bull in Journal of Empirical Research on Human Research Ethics
Cascaded Fractional Kalman Filtering for State and Current Estimation of Large-Scale Lithium-Ion Battery Packs
Creators: name: Kupper, Martin
name: Brenneisen, Jochen
name: Stark, Oliver
name: Krebs, Stefan
name: Hohmann, Sören
Publisher: name: Karlsruhe
Year: 2018
Subjects: State of Charge estimation
Current estimation
Kalman filter
Cascaded systems
Fractional order
Battery pack
Large-scale
Lithium-ion

description: In this paper, a cascaded fractional Kalman filter for state of charge and branch current estimation of large-scale battery systems is proposed. As a centralized approach for the estimation of a large-scale system is costly in terms of effort and time, a partition into smaller and, therefore, simpler subsystems is applied. Since the overall system is divided into smaller units, a local computation is allowed and complexity reduced. In these distributed systems, usually, the subsystems communicate with each other to exchange relevant data. Using a model based on mesh currents, we receive a cascaded system structure which results in a hierarchical arrangement of all subsystems. This concludes in a one-directional information flow and, therefore, reduces the overall communication effort. Using this proposed approach, it is not only possible to estimate the states of each branch locally but also to calculate the branch currents when the total current is known. Finally, a practical test with real measurement data is presented.
Additional file 1 of Healthcare provider perspectives on integrating a comprehensive spine care model in an academic health system: a cross-sectional survey
Creators: name: Burton, Wren
name: Salsbury, Stacie A.
name: Goertz, Christine M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. STROBE Statement—checklist of items that should be included in reports of observational studies.
Organisational quality and hospital pharmacists’ roles of outpatient parenteral antimicrobial therapy (OPAT) in Belgian hospitals: a national survey
Creators: name: Kaes, Anneleen
name: Buyle, Franky
name: Quintens, Charlotte
name: Van Eijgen, Astrid
name: Zubryckyj, Larissa
name: Boussery, Koen
name: Vanoverschelde, Anna
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Computational Biology

description: Implementation of outpatient parenteral antimicrobial therapy (OPAT), also known as intravenous (IV) antimicrobial treatment at home, has increased in recent years. Ensuring OPAT quality is crucial to achieve positive patient outcomes. However, data on the Belgian quality of OPAT organisation is lacking. We aimed to monitor the organisational quality of OPAT in Belgian hospitals and identify roles of hospital pharmacists involved in OPAT. A cross-sectional study applying a web-based survey on OPAT quality was conducted from 2 to 29 April 2024. The survey assessed the presence of six core and five non-core structure indicators, and OPAT-related tasks of hospital pharmacists. Almost two-thirds (64%; 65/101) of Belgian hospitals answered the survey, with 77% of these hospitals providing OPAT, with an increase since 2023. All 11 structure indicators were present in 6% of hospitals, while 18% had all six core structure indicators. Three of the six core structure indicators were formally present in the majority of the hospitals: a policy on patient selection criteria (76%), a structured OPAT programme (70%), and a dedicated team (64%). In contrast, a system for fast communication between the patient and OPAT team members (50%), a mechanism for urgent clinical discussions (42%), and monitoring of quality indicators (28%) were not formally present in the majority of the hospitals. The primary tasks for hospital pharmacists included overseeing OPAT prescriptions and supplying antimicrobials and related materials. While the adoption of OPAT is increasing among Belgian hospitals, significant opportunities remain for improving the quality of the OPAT organisation and expanding the OPAT-related tasks of Belgian hospital pharmacists.
title: Die filmische Realisierung dänischer literarischer Werke
Creators: name: Reinprecht, Elisabeth
Year: 2008

description: zwischen Gabriel Axels Babettes Fest und Ole Christian Madsens Nordkraft Die vorliegende Arbeit macht sich zum Ziel, zwei herausragende Werke der dänischen Filmgeschichte genauer zu untersuchen. Als Einführung wird ein Abriss der dänischen Filmgeschichte gegeben, der dem/der Leser/in die künstlerische, als auch wirtschaftliche Entwicklung, von der Zeit des Stummfilms bis hin zur Etablierung einer international anerkannten und konkurrenzfähigen Filmnation, veranschaulichen soll. Im Anschluss daran, werden die Schwierigkeiten und Herausforderungen der Umsetzung eines literarischen Werkes in das Medium Film diskutiert. Hier wird unter anderem darauf hingewiesen, dass das grundlegende Prinzip jeder filmischen Adaption darin liegen sollte, die literarische Vorlage nicht schlechterdings zu kopieren, sondern vielmehr ein Produkt zu schaffen, dass den Grundgedanken des Originals bewahrt und dennoch unabhängig von diesem, als eigenständiges Kunstwerk zu charakterisieren ist. In der Folge werden zwei eindrucksvolle literarische Werke und ihre filmischen Realisierungen vorgestellt und analysiert. Als erstes wird auf die Verfilmung von Karen Blixens Kurzgeschichte Babettes Fest näher eingegangen. Nachdem die Vorlage beschrieben und interpretiert worden ist, wird der im Jahr 1987 entstandene Film nach einer Methode der Medien- und Filmwissenschaftler Thomas Kuchenbuch und Werner Faulstich analysiert, um in weiterer Folge eventuelle Abweichungen und ihre Folgen für die Interpretation des Textes zu besprechen. Analog zu diesem Teil, wird auch die Transformation von Jakob Ejersbos Nordkraft unter die Lupe genommen. Ziel der Analysen ist es, aufzuzeigen, welche filmästhetischen Mittel eingesetzt und ausgeschöpft wurden, um die Essenz des Textes, in dem/für das Medium Film neu zu formulieren. Die künstlerischen Fähigkeiten der Regisseure, als auch der SchauspielerInnen, werden hier auf die Probe gestellt. Im abschließenden Kapitel, der vergleichenden Analyse, werden die einzelnen Aspekte der filmischen Umsetzung hervorgehoben, miteinander konfrontiert und diskutiert. In diesem Abschnitt treten schließlich die Qualitäten, aber auch eventuelle Mängel der Transformationen in den Vordergrund. Im letzten Teil der Arbeit wird eine abschließende, filmästhetische Bewertung vorgenommen, die ermisst, inwieweit alle, dem Medium Film eigentümlichen Wirkungsmittel eingesetzt wurden, um letztendlich ein Urteil darüber abgeben zu können, inwieweit die filmischen Werke von Gabriel Axel und Ole Christian Madsen als gelungen/misslungen zu betrachten sind bzw. ob die Filmschaffenden ihre Aufgabe, eigenständige Kunstwerke hervorzubringen, erfüllt haben.
Remimazolam induced cytotoxicity mediated through multiple stress pathways and acted synergistically with tyrosine kinase inhibitors in hepatocellular carcinoma
Creators: name: Fan, Hsiu-Lung
name: Chen, Jia-Lin
name: Liu, Shu-Ting
name: Lee, Jia-Tong
name: Huang, Shih-Ming
name: Wu, Zhi-Fu
name: Lai, Hou-Chuan
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: The primary treatment for hepatocellular carcinoma (HCC) involves surgical removal of the primary tumor, but this creates a favorable environment for the proliferation and spread of residual and circulating cancer cells. The development of remimazolam-based balanced anesthesia is crucial for future antitumor applications. It is important to understand the mechanisms of cytotoxicity for HCC in detail. We performed cell viability analysis, western blotting analysis, reverse transcription–polymerase chain reaction analysis, and flow cytometry analysis in two HCC cell lines, HepG2 and Hep3B cells. Our data demonstrated that remimazolam induced cytotoxicity by suppressing cell proliferation, inhibiting G1 phase progression, and affecting mitochondrial reactive oxygen species (ROS) levels, leading to apoptosis, DNA damage, cytosolic ROS elevation, lipid peroxidation, autophagy, mitochondrial depolarization, and endoplasmic reticulum stress. Inhibitors of apoptosis, autophagic cell death, and ferroptosis and a ROS scavenger failed to rescue cell death caused by remimazolam besylate. Our combination index revealed that remimazolam besylate has the potential to act as a sensitizer for targeted tyrosine kinase inhibitor therapy for HCC. Our findings open up new possibilities for combinatory HCC therapy using remimazolam, leveraging its dual functional roles in surgery and drug therapy for liver cancers.
Additional file 2 of Healthcare provider perspectives on integrating a comprehensive spine care model in an academic health system: a cross-sectional survey
Creators: name: Burton, Wren
name: Salsbury, Stacie A.
name: Goertz, Christine M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2.
The Taylor-von Neumann-Sedov blast-wave solution: comparisons with microscopic simulations of a one-dimensional gas
Creators: name: Ganapa, Santhosh
name: Chakraborti, Subhadip
name: Krapivsky, P. L.
name: Dhar, Abhishek
Publisher: name: arXiv
Year: 2020
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Computational Physics (physics.comp-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We study the response of an infinite system of point particles on the line initially at rest on the instantaneous release of energy in a localized region. We make a detailed comparison of the hydrodynamic variables predicted by Euler equations for non-dissipative ideal compressible gas and the results of direct microscopic simulations. At long times the profiles of the three conserved variables evolve to self-similar scaling forms, with a scaling exponent as predicted by the Taylor-von Neumann-Sedov (TvNS) blast-wave solution. The scaling functions obtained from the microscopic dynamics show a remarkable agreement with the TvNS predictions, except at the blast core, where the TvNS solution predicts a diverging temperature which is not observed in simulations. We show that the effect of heat conduction becomes important and present results from a numerical solution of the full Navier-Stokes-Fourier equations. A different scaling form is observed in the blast core and this is carefully analyzed. Our microscopic model is the one-dimensional alternate mass hard-particle gas which has the ideal gas equation of state but is non-integrable and known to display fast equilibration.
description: 17 pages, 11 figures
Supplemental Material - Collaborating and co-creating the digital transformation: Empirical evidence on the crucial role of stakeholder demand from Swiss municipalities
Creators: name: Weißmüller, Kristina S
name: Ritz, Adrian
name: Yerramsetti, Srinivas
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 160509 Public Administration
subject: 160512 Social Policy

description: Supplemental Material for Collaborating and co-creating the digital transformation: Empirical evidence on the crucial role of stakeholder demand from Swiss municipalities by Kristina S Weißmüller, Adrian Ritz and Srinivas Yerramsetti in Public Policy and Administration
title: Zur Rolle des Hörens im Deutsch als Zweitspracheunterricht
Creators: name: Klinglmair, Anita Maria
Year: 2008

description: Die Fertigkeit Hören soll im Sprachunterricht für MigrantInnen einen bedeutenden Stellenwert einnehmen. Dabei eingesetztes Hörmaterial kann mehrere Bereiche abdecken: Die Ebene des Hörverstehens mit den Hörtexten, die phonologische Ebene als Teil des Hörverstehens und der Ausspracheschulung und die Ebene des Hörens von Musik, Geräusch und Klang. Diese Arbeit skizziert kurz die Lebens- und Sprachlernsituation von MigrantInnen und geht dabei auf wesentliche Einflussfaktoren im Zweitsprachenunterricht ein: Muttersprache und soziokulturelle Prägung der Lernenden, gesteuerter und ungesteuerter Spracherwerb und Lehr- und Lernmaterialien. Die Entwicklung der Fertigkeit Hören im Fremd- und Zweitsprachenunterricht und der gegenwärtige Stand der Forschung zum Hörverstehen werden erläutert, weiters wird auf zentrale Begriffe von Hörtexten wie Authentizität und Aussprachestandards eingegangen und eine Übersicht über Texttypen gesprochener Sprache gegeben. Im Anschluss werden die Hörmaterialien dreier im Zweitsprachenunterricht eingesetzten Lehrwerke Delfin 2, Tangram aktuell 2 und Schritte 3 und 4 hinsichtlich ihrer Eignung im Unterricht mit MigrantInnen untersucht. Dabei werden Kriterien im Sinne einer Lehrwerkanalyse herausgearbeitet, mit deren Hilfe die drei Bereiche des Hörmaterials analysiert werden: 1) Hörtexte, 2) Hörmaterial zur Phonetik und 3) Instrumentalmusik, Geräusch und Klang. Ein Vergleich der Hörmaterialien der einzelnen Lehrwerke zeigt deren unterschiedliche Stärken und Schwächen für den Einsatz im Zweitsprachenunterricht auf. Aus den Ergebnissen der Untersuchung lässt sich die Forderung an Lehrwerke stellen, dass im Lehr- bzw. Lernmaterial für MigrantInnen authentische Hörtexte stärker berücksichtigt werden, die österreichische Standardvarietät und verschiedene Varianten der deutschen Sprache vermehrt vertreten sind und der Bereich Musik, Geräusch und Klang ausgebaut wird.
Homology-changing percolation transitions on finite graphs
Creators: name: Woolls, Michael
name: Pryadko, Leonid
Publisher: name: arXiv
Year: 2020
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider homological edge percolation on a sequence $(\mathcal{G}_t)_t$ of finite graphs covered by an infinite (quasi)transitive graph $\mathcal{H}$, and weakly convergent to $\mathcal{H}$. Namely, we use the covering maps to classify $1$-cycles on graphs $\mathcal{G}_t$ as homologically trivial or non-trivial, and define several thresholds associated with the rank of thus defined first homology group on the open subgraphs. We identify the growth of the homological distance $d_t$, the smallest size of a non-trivial cycle on $\mathcal{G}_t$, as the main factor determining the location of homology-changing thresholds. In particular, we show that the giant cycle erasure threshold $p_E^0$ (related to the conventional erasure threshold for the corresponding sequence of generalized toric codes) coincides with the edge percolation threshold $p_{\rm c}(\mathcal{H})$ if the ratio $d_t/\ln n_t$ diverges, where $n_t$ is the number of edges of $\mathcal{G}_t$, and we give evidence that $p_E^0
Enhancing Adaptive Spline Regression: An Evolutionary Approach to Optimal Knot Placement and Smoothing Parameter Selection
Creators: name: Thielmann, Anton
name: Kneib, Thomas
name: Säfken, Benjamin
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Standard approaches for nonparametric curve fitting are often too restrictive when trying to estimate covariate effects that feature sudden changes or drastically changing curvature. In this context, adaptive smoothing approaches have received a lot of attention, but are typically limited in their ability to study additive models with multiple covariate effects, the consideration of nonnormal data and/or distributional regression scenarios, and usually rely on either optimizing number and location of knots for the basis functions in nonparametric smoothing or on making the smoothing parameter covariate-dependent. Another inherent problem lies in the independent optimization of knots and smoothing parameters, overlooking the essential interdependence that ensures accurate modeling results. In this article, we propose an approach based on particle swarm optimization that overcomes these limitations and shows very promising performance in complex simulations and applications. Our methodology is adaptable to all types of splines, including univariate and multivariate, and extends to regression techniques beyond the mean, such as models for location, scale and shape and additive quantile regression. The source code is available at https://github.com/AnFreTh/OKPSPS. Supplementary materials for this article are available online.
Additional file 1 of Point-of-care testing and antibiotics prescribing in out-of-hours general practice: a register-based study in Denmark
Creators: name: Christensen, Line Due
name: Vestergaard, Claus Høstrup
name: Keizer, Ellen
name: Bech, Bodil Hammer
name: Bro, Flemming
name: Christensen, Morten Bondo
name: Huibers, Linda
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. STROBE Statement—checklist of items that should be included in reports of observational studies.
Additional file 2 of Point-of-care testing and antibiotics prescribing in out-of-hours general practice: a register-based study in Denmark
Creators: name: Christensen, Line Due
name: Vestergaard, Claus Høstrup
name: Keizer, Ellen
name: Bech, Bodil Hammer
name: Bro, Flemming
name: Christensen, Morten Bondo
name: Huibers, Linda
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Table A1. Contact- and patient characteristics for all clinic consultations, stratified for use of POCTs.
title: Algodón :
title: Directrices para la ejecución del examen de la distinción, la homogeneidad y la estabilidad.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants..,
Publisher: name: International Union for the Protection of New Varieties of Plants
Year: 0
Subjects: New Varieties of Plants
Cotton
Group identity.

description: La finalidad de estas directrices (“directrices de examen”) es elaborar los principios que figuran en la Introducción General (documento TG/1/3) y sus documentos TGP conexos, con objeto de que sirvan de orientación práctica y detallada para el examen armonizado de la distinción, homogeneidad y estabilidad (DHE) y en particular, para identificar los caracteres apropiados para el examen DHE y producir descripciones armonizadas de variedades.
sj-docx-2-pdp-10.1177_10935266231213464 – Supplemental material for Diminished TMEM100 Expression in a Newborn With Acinar Dysplasia and a Novel TBX4 Variant: A Case Report
Creators: name: Szafranski, Przemyslaw
name: Patrizi, Silvia
name: Gambin, Tomasz
name: Afzal, Bushra
name: Schlotterbeck, Emily
name: Karolak, Justyna A.
name: Deutsch, Gail
name: Roberts, Drucilla
name: Stankiewicz, Paweł
Publisher: name: SAGE Journals
Year: 2023
Subjects: Paediatrics
Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-2-pdp-10.1177_10935266231213464 for Diminished TMEM100 Expression in a Newborn With Acinar Dysplasia and a Novel TBX4 Variant: A Case Report by Przemyslaw Szafranski, Silvia Patrizi, Tomasz Gambin, Bushra Afzal, Emily Schlotterbeck, Justyna A. Karolak, Gail Deutsch, Drucilla Roberts and Paweł Stankiewicz in Pediatric and Developmental Pathology
Gender differences in estrogenic compounds effect on human EPCs
Creators: name: Campesi, Ilaria
name: Capobianco, Giampiero
name: Dessole, Salvatore
name: Franconi,
name: Montella, Andrea
Publisher: name: Firenze University Press
Year: 2017
Subjects: EPCs; gender; migration; estrogenic compounds

description: Endothelial dysfunction has been defined as an “integrated risk factor”, and several gender difference have been reported in endothelial function. Several evidences suggest that endothelial progenitor cells (EPCs) are an important endogenous system that maintains integrity and vascular homeostasis. Their function is regulated by estrogens and estrogen receptors (ERs), but the effect of estrogenic compounds such as bisphenol A (BPA) and (R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol (THC) on human EPCs is unknown. BPA is used in plastic industry and BPA exposure is associated to abnormalities such as obesity, diabetes, disorders of the reproductive and immune systems, to endothelial dysfunction, and oxidative stress. This endocrine disruptor binds to ERα and ERβ with higher affinity for ERβ. THC is a specific agonist of ERα with a stronger ERβ antagonist activity. Therefore, the present work aimed to analyze if BPA and THC influence in a sex-specific manner the migration of human EPCs, an essential process in endothelial regeneration after vascular injury. EPCs were isolated from healthy adult men and women aged between 18 and 30 years, using a magnetic positive selection with the CD34 MicroBeads, a well-established marker of human progenitor cells. EPCs were also characterized for acetylated LDL Dil- (acLDL) and isothiocyanate (FITC)-conjugated with Ulex europaeus agglutinin I (lectin) uptake. The expression of ERα and ERβ was analysed by Western Blotting, while the migration assay was performed with the transwell chemotaxis assay. Male and female EPCs expressed both classical ERs: ERα was higher, but not significantly, in female cells, while ERβ was similarly expressed in both sexes. Male and female EPCs did not differ in basal migration. 17-β-estradiol (10-9 M e 10-10 M) significantly inhibited migration in female EPCs but not in male ones. Moreover, both 10-5 M THC and BPA (10-8 M) were able to bock migration only in female cells. Considering that BPA has a ERα and a prevalent ERβ agonist activity while THC has ERα agonistic activity and a prevalent ERβ antagonist activity, our data show that the effect on migration observed in female EPCs is mediated by ERα. Our data demonstrate that estrogenic compound have a sexual divergent effect on human EPCs, improving our knowledge on the gender differences observed in the pathophysiology of endothelial function.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Direct effects of estrogens on cholinergic primary neurons from the human fetal nucleus basalis of Meynert
Creators: name: Morelli, Annamaria
name: Guarnieri, Giulia
name: Sarchielli, Erica
name: Comeglio, Paolo
name: Vannelli, Gabriella
Publisher: name: Firenze University Press
Year: 2017
Subjects: Neuroinflammation; GPR30; Alzheimer’s disease

description: Epidemiological studies have indicated that Alzheimer’s disease (AD) is more common in females and that post-menopausal women are at increased risk than their male counterpart, thus suggesting that estrogens could play a protective role to counteract neurodegenerative processes (1). However, the mechanisms underlying this association remain to be clarified. Since the nucleus basalis of Meynert (nbM) is the major source of cholinergic innervation selectively vulnerable to degeneration in AD, our study is aimed at investigating the effects of estrogens on human cholinergic primary neurons (hfCNs) isolated from the nbM of 12-week old fetuses. The primary culture obtained was immunophenotyped with flow cytometry and resulted almost totally positive (97±2 %) for the neuronal marker MAP2 and for the choline acetyltransferase (ChAT). We demonstrated that hfCNs express receptors for hormones of the reproductive axis (ERs, LHR, GnRHR). In particular, besides to classical estrogen receptors (ERa and ERb), hfCNs express the transmembrane receptor GPR30, which is known to mediate rapid non-genomic estrogen actions. Increasing concentrations of 17-β estradiol (E2, 0.1-100 nM) determined a dose-dependent significant increase in cell number after 24h exposure, which was antagonized by tamoxifen treatment. In addition, E2 exposure determined a significant increase in ChAT expression, thus indicating a direct positive effect of E2 on cholinergic phenotype. Given that substantial evidence now indicates that estrogens exert an anti-inflammatory activity even in the central nervous system (2), we exposed hfCN cells to the proinflammatory cytokine TNFα. E2 treatment (1nM) was able to significantly counteract the TNFα-induced nuclear NF-kB p65 translocation. Interestingly, this effect was mimicked by G1, a GPR30 agonist, and abolished by pretreating cells with the GPR30 antagonist G15, but not by tamoxifen, which usually antagonizes classical ERs. Overall, our results indicate that estrogens exert direct neuroprotective mechanisms on hfCNs through the activation of either classical (trophic) and non-classical (anti-inflammatory) receptors.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Tunable quantum logic gate on photonic qubits with a ladder emitter
Creators: name: Wang, Derek S.
name: Dai, David D.
name: Narang, Prineha
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: Applied Physics (physics.app-ph)
subject: Atomic Physics (physics.atom-ph)
subject: Computational Physics (physics.comp-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We present a scheme to implement a passive and deterministic controlled-variable phase gate on photonic qubits encoded in the frequency basis. Our gate employs a cascade system with the ground to first excited state interacting with the control photon of a given polarization, and the first to second excited state transition interacting with the target photon of the orthogonal polarization. By controlling the relative detuning between the target photon and the frequency of the transition between the first and second excited states of the cascade emitter, we enable any controlled-phase operation from 0 to $π$. This gate does not utilize any active control and needs only a single cascade emitter, enabling low-footprint and more efficient decomposition of quantum circuits, especially those rooted in the quantum Fourier transform.
description: 10 pages, 3 figures, and 2 tables
Ameliorative effect of VIP family members on blood retinal barrier breakdown in diabetic macular edema
Creators: name: D’Amico, Agata Grazia
name: Reitano, Rita
name: Federico, Concetta
name: Saccone, Salvatore
Publisher: name: Firenze University Press
Year: 2017
Subjects: PACAP; VIP; diabetic macular edema; blood-retinal barrier

description: Diabetic macular edema (DME) is one of the main complications of diabetic retinopathy [1]. This pathology is owed to impairment of the blood-retinal barrier (BRB) [2]. Many factors, such as hypoxia, contribute to barrier dysfunction and progression of the disease. Low oxygen tension is one of the main events involved in the formation of new blood vessels that characterize the typical uncontrolled angiogenesis in proliferative stage of diabetic retinopathy. In the last decades, various studies have focused their attention on the role of pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) in the pathophysiology of DME. However, the effects of these peptides in maintaining the integrity of the BRB exposed to hypoxia remains to be elucidated. In the present work we have studied, for the first time, the effect of these peptides on outer BRB integrity following hypoxic insult in an experimental model of DME. To this end, we have used the human retinal pigment epithelial cells (ARPE-19) to test the effect of both peptides on cellular permeability, transepithelial electrical resistance, tight junctions expression and hypoxia-induced apoptosis. Results have demonstrated that both PACAP and VIP are able to rescue the integrity of cell monolayer during the hypoxic event, minimizing apoptotic damages induced by low tissue oxygen tension through the activation of phosphoinositide 3 kinase /Akt and mammalian mitogen activated protein kinase/Erk kinase signaling pathways. Furthermore, these peptides modulate the expression of vascular endothelial growth factor which is one of the downstream transcription factor activated during the hypoxic process. In conclusion, we have demonstrated that PACAP and VIP are able to counteract the damage induced by hypoxia on BRB through the modulation of hypoxia inducible factors expression.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Vasopressin induces cholangiocyte proliferation in experimental cholestasis and in Polycystic Liver Disease
Creators: name: Mancinelli, Romina
name: Pannarale, Luigi
name: Glaser, Shannon
name: Alpini, Gianfranco
name: Onori, Paolo
Publisher: name: Firenze University Press
Year: 2017
Subjects: Biliary epithelium; vasopressin; cholestasis; polycystic liver disease

description: The hormone vasopressin (hereafter AVP) is a neuropeptide mainly synthesized in the brain’s hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei, works by three distinct receptor subtypes: V1a, V1b, and V2 [1]. In liver, AVP is involved in glycogenolysis and neoglucogenesis and regenerative processes [2]. Cholangiocytes are the cells that line the biliary ducts and they are the target in a number of animal models of cholestasis including bile duct ligation (BDL) and in several human pathologies such as polycystic liver disease (PLD) characterized by the presence of numerous cysts within the liver that arise from biliary epithelium [3]. Since no data exist about the presence and the role of AVP and receptors in biliary epithelium, we aimed to evaluate the effects of AVP in experimental model of cholestasis and in course of PLD. In vivo, normal and BDL liver fragments from rats, normal and PLD from human patients were collected to evaluate: (i) intrahepatic bile duct mass (IBDM) by immunohistochemistry for citokeratin-19 (CK-19); and (ii) expression of V1a, V1b and V2 by immunohistochemistry, immunofluorescence and real time PCR. In vitro, small and large mouse cholangiocytes, H69 (non-malignant human cholangiocytes) and LCDE (human cholangiocytes from cystic epithelium) were stimulated with AVP in the absence/presence of antagonists such as OPC-31260 and Tolvaptan, before assessing cellular growth by MTT proliferation assay, cAMP levels by a RIA kit and the expression of some angiogenic factors, such as platelet-derived growth factor (PDGF) and Angiopoietins (Ang-1 and Ang-2). Cholangiocytes express V2 receptor that was upregulated following BDL and in course of polycystic disease. Treatment with AVP of cholangiocyte cultures increased proliferation, cAMP levels and expression of PDGF, Ang-1, Ang-2 in small cholangiocytes and LCDE cells. These increments were blocked by pre-incubation with the AVP antagonists. Our results showed that AVP play an important role in growth of the biliary epithelium during cholestasis and in cystic epithelium in course of PLD acting on the cAMP signalling pathway and increasing angiogenic factors. Additional studies are necessary, but these first results may be considered important in the regulation of the biliary growth/loss in course of cholangiopathies.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
sj-docx-1-cnr-10.1177_10547738231211980 – Supplemental material for Technology-Based Health Promotion Training Among Stroke Patients: A Randomized Controlled Trial
Creators: name: BAL, Cansev
name: KOÇ, Zeliha
Publisher: name: SAGE Journals
Year: 2023
Subjects: Nursing not elsewhere classified

description: Supplemental material, sj-docx-1-cnr-10.1177_10547738231211980 for Technology-Based Health Promotion Training Among Stroke Patients: A Randomized Controlled Trial by Cansev BAL and Zeliha KOÇ in Clinical Nursing Research
Additional file 3 of Point-of-care testing and antibiotics prescribing in out-of-hours general practice: a register-based study in Denmark
Creators: name: Christensen, Line Due
name: Vestergaard, Claus Høstrup
name: Keizer, Ellen
name: Bech, Bodil Hammer
name: Bro, Flemming
name: Christensen, Morten Bondo
name: Huibers, Linda
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3: Figure A1. GPs’ tendency to use POC testing, for different GP characteristics, stratified by CRP test, RADT, and urine dipsticks. Unadjusted binomial regression (relative PUT and 95% confidence interval).