cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The nutrition transition to a stage of high obesity and noncommunicable disease prevalence dominated by ultra-processed foods is not inevitable
Creators: name: Popkin B.M
name: Ng S.W
Publisher: name: John Wiley and Sons Inc
Year: 2022

description: The Nutrition Transition model is presented with the nature and pace of change in key stages varying by location and subpopulations. At present, all high-income and many low- and middle-income countries are in a stage of the transition where nutrition-related noncommunicable diseases including obesity, type 2 diabetes, and hypertension are dominating adult morbidity and mortality and are very high or growing rapidly in prevalence. Some countries still have key subpopulations facing hunger and undernutrition defined by stunting or extreme thinness among adults. We call these double burden of malnutrition countries. All low- and middle-income countries face rapid growth in consumption of ultra-processed food and beverages, but it is not inevitable that these countries will reach the same high levels of consumption seen in high-income countries, with all the negative impacts of this diet on health. With great political and civil society commitment to adoption of policies shown in other countries to have improved dietary choices and social norms around foods, we can arrest and even reverse the rapid shift to diets dominated by a stage of high ultra-processed food intake and increasing prevalence of nutrition-related noncommunicable diseases.
Correre… ai ripari: come salvare una società atletica ticinese dalla sua più grande perdita di sempre
Creators: name: Lucchina, Emma
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2021
Subjects: [TESI CONFIDENZIALE]

description: [TESI CONFIDENZIALE] La pandemia da COVID-19 ha colpito duramente molti settori dell’economia mondiale e tra questi anche quello dello sport dilettantistico. Tra le numerose associazioni in difficoltà si è deciso di analizzare la situazione della società atletica VIGOR Ligornetto che nel distretto di Mendrisio porta avanti da decenni un’importante attività sul territorio. La società deve le sue principali entrate ai numerosi sponsor, alle quote di iscrizione dei propri atleti e ai sussidi delle federazioni cappello, ma deve molti dei suoi introiti anche a manifestazioni paesane, vendita di generi alimentari e grigliate organizzate sul territorio. A causa delle condizioni dettate dalla pandemia sono purtroppo venute a mancare delle preziose entrate già nell’anno 2020 da cui è conseguita un’ingente perdita a fine anno. Lo scopo del presente elaborato è quello di analizzare la situazione attuale, avere un confronto con i membri di alcune altre società atletiche ticinesi, ricercare delle possibili soluzioni e valutarne l’applicabilità con i relativi vantaggi e sfide.
title: Shear Viscosity for QCD at High Chemical Potentials
Creators: name: Danhoni, Isabella
Publisher: name: UNSPECIFIED
Year: 2024

description: Quark-gluon plasma (QGP) is generated in lower-energy collisions with a high net baryon
number. Consequently, the baryon chemical potential µ B is several times higher than
the temperature T . This regime cannot be directly studied on the lattice; therefore, the
high-density region of the QCD phase diagram is not as well understood as the µ B = 0
axis. At high temperatures, one can claim that the perturbative series should work better
at a high chemical potential, such that µ B > T > T c , than in the case of µ B = 0[41]. Due
to the strongly coupled nature of soft gluons, perturbation theory fails in hot QCD before
the coupling becomes large [62]. However, at high chemical potential, the scattering
from quarks is enhanced by a factor of µ 2 B /T 2 , and one expects the perturbative series
to behave better. With this motivation, we study the influence of chemical potentials on
the QCD shear viscosity in this thesis. Namely, we extend the Arnold-Moore-Yaffe (AMY)
calculations for shear viscosity at leading log [13] in weakly coupled high-temperature and
dense QCD[41]. Following this, we also perform a study of shear viscosity with multiple
conserved charges, baryonic (B), strangeness (S), and electric (C), using the leading log
treatment. After that, we extend the high-density calculations to leading perturbative
order, first calculated in [9] for vanishing chemical potentials, and to ”almost” next to the
leading order, based on the work from Ghiglieri et al. [62]. With these results, we test
the convergence of the perturbative series. Finally, in a complementary work, we study
the shear-stress linear response function and investigate the existence of a branch cut
touching the origin in a system of scalar self-interacting particles with quartic interactions.
The processed food revolution in African food systems and the double burden of malnutrition
Creators: name: Vargas C
name: Sauer C
name: Vos R
name: Liverpool-Tasie L.S.O
name: Fanzo J
name: Lartey A
name: Popkin B.M
name: Awokuse T
name: Minten B
name: Tschirley D
name: Raza A
name: Reardon T
name: Dhar R
name: Dolislager M
Publisher: name: Elsevier B.V.
Year: 2021

description: African consumers have purchased increasing amounts of processed food over the past 50 years. The opportunity cost of time of women and men has increased as more of them work outside the home, driving them to buy processed food and food prepared away from home to save arduous home-processing and preparation labor. In the past several decades, this trend has accelerated with a surge on the supply side of the processing sector and small and medium enterprises (SMEs) and large private companies making massive aggregate investments. Packaged, industrialized, ultra-processed foods and sugar-sweetened beverages (SSBs) are a growing proportion of the processed food consumed. Also, in the past several decades, overweight and obesity have joined the long-standing high levels of stunting and wasting among children and extreme thinness among women of childbearing age. Together these phenomena have formed a double burden of malnutrition (DBM). The DBM has emerged as an important health problem in sub-Saharan Africa. The rise of the DBM and the increase in ultra-processed food consumption are linked. Policy makers face a dilemma. On the one hand, purchases of processed food are driven by long-term factors, such as urbanization, increased income, and employment changes, and thus policy cannot change the pursuit of convenience and labor-saving food. Moreover, much processed food, like packaged milk, is a boon to nutrition, and the processed food system is a major source of jobs for women. On the other hand, the portion (some 10–30%) of processed food that is ultra-processed is a public health challenge, and policy must address its detrimental effects on disease burden. The global experience suggests that double duty actions are most important as are selected policies focused on healthy weaning foods for addressing stunting and taxes on SSBs, nutrition labeling, and other measures can steer consumers away from unhealthy ultra-processed foods to addressing obesity and possibly child nutrition and stunting. We recommend that African governments consider these policy options, but note that the current extreme fragmentation of the processing sector, consisting of vast numbers of informal SMEs in sub-Saharan Africa, and the limited administrative/implementation capacity of many African governments require pursuing this path only gradually.
The promises and perils of psychedelic pharmacology for psychiatry
Creators: name: McClure-Begley T.D
name: Roth B.L
Publisher: name: Nature Research
Year: 2022

description: Psychedelic drugs including psilocybin, N,Nʹ-dimethyltryptamine (DMT) and lysergic acid diethylamide (LSD) are undergoing a renaissance as potentially useful drugs for various neuropsychiatric diseases, with a rapid onset of therapeutic activity. Notably, phase II trials have shown that psilocybin can produce statistically significant clinical effects following one or two administrations in depression and anxiety. These findings have inspired a ‘gold rush’ of commercial interest, with nearly 60 companies already formed to explore opportunities for psychedelics in treating diverse diseases. Additionally, these remarkable phenomenological and clinical observations are informing hypotheses about potential molecular mechanisms of action that need elucidation to realize the full potential of this investigative space. In particular, despite compelling evidence that the 5-HT2A receptor is a critical mediator of the behavioural effects of psychedelic drugs, uncertainty remains about which aspects of 5-HT2A receptor activity in the central nervous system are responsible for therapeutic effects and to what degree they can be isolated by developing novel chemical probes with differing specificity and selectivity profiles. Here, we discuss this emerging area of therapeutics, covering both controversies and areas of consensus related to the opportunities and perils of psychedelic and psychedelic-inspired therapeutics. We highlight how basic science breakthroughs can guide the discovery and development of psychedelic-inspired medications with the potential for improved efficacy without hallucinogenic or rewarding actions.
Manifestazioni aggressive e violenza in pronto soccorso: il ruolo dell’infermiere nella gestione di queste situazioni
Creators: name: Cantiani Felappi, Oliviero
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2016
Subjects: Aggressività
violenza
reparti di pronto soccorso
ruolo dell’infermiere

description: Tema e obiettivi Attraverso questo lavoro si è voluto mettere il luce il problema dell’aggressività e della violenza sul posto di lavoro nei confronti del personale curante dei reparti di pronto soccorso. In particolar modo si è voluta constatare la reale entità di questa problematica sia a livello globale sia a livello territoriale del Canton Ticino soffermandosi sul ruolo che l’infermiere ricopre nel caso in cui si verifichino tali episodi. Metodologia La redazione del seguente lavoro si è svolta in due parti. Dapprima è stata effettuata una revisione della letteratura a partire da testi e articoli attraverso le banche dati o forniti da persone operanti all’interno dell’ambito sanitario. Per la ricerca di questi articoli sono state impiegate banche dati come PubMed, CINHAL, Cochrane library utilizzando parole chiave quali “violence”, “violent”, “aggression”, “aggressivity”, “aggressive”, “abuse”, “emergency department”, “nurses”, “hospital”. In secondo luogo è stata svolta una ricerca qualitativa sul campo attraverso delle interviste semi strutturate ai capi reparto dei vari ospedali appartenenti all’Ente Ospedaliero Cantonale. Successivamente alle interviste sono state redatte delle tabelle analitiche al fine di confrontare i dati emersi da queste ultime. Infine è stata fatta una discussione in modo tale da paragonare quanto emerso dalla letteratura scientifica con quanto emerso dalle interviste. Risultati Dall’analisi dei risultati e dalla discussione emerge come la maggior parte dei dati riportati dalla letteratura globale sia confermata dalle interviste effettuate sul suolo ticinese. Grazie alle interviste è emerso come questa problematica sia presente anche in una realtà piccola come la nostra seppur con delle piccole differenze dovute appunto ai diversi contesti. Nei reparti ticinesi sono state adottate misure preventive e di sostegno al personale nell’ambito del processo globale di promozione e valutazione della qualità. Parole chiave Aggressività, violenza, reparti di pronto soccorso, ruolo dell’infermiere
CARMOLIT 2014 LEG1 cruise,Côtes De La Manche R/V
Creators: name: QUEMENER Loïc
Publisher: name: Sismer
Year: 2014

description: Mouillage de la bouée Molit en baie de Vilaine pour sa campagne de mesure annuelle. L'oxygène, la température, la salinité, la turbidité et la fluorescence sont mesurées au fond et en surface alternativement toutes les 30 minutes.
Puccinellia caesia L.
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S. caesia L. Cat. 155und 426. l: Dents-du-Midi (Beauverd).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Dysschema imitata
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Dysschema
Dysschema imitata

description: Dysschema imitata (Druce, 1910)
Pericopis imitata Druce, 1910: 170.
TYPE LOCALITY. — Peru, [Puno], Limbani, Carabaya, Rio Huacamayo, Oconeque, Agualani; Brazil.
TYPE SPECIMENS. — Described from 11 male and 1 female syntypes (BMNH; one male syntype from Limbani labeled TYPE).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 473, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Search for a resonance decaying into a scalar particle and a Higgs boson in the fnal state with two bottom quarks and two photons in proton–proton collisions at √s = 13 TeV with the ATLAS detector
Creators: name: ATLAS Collaboration
Publisher: name: Springer Berlin Heidelberg
Year: 2024

description: A search for the resonant production of a heavy scalar X decaying into a Higgs boson and a new lighter scalar S, through the process X → S(→ b b ¯ )H(→γγ), where the two photons are consistent with the Higgs boson decay, is performed. The search is conducted using an integrated luminosity of 140 fb−1 of proton-proton collision data at a centre-of-mass energy of 13 TeV recorded with the ATLAS detector at the Large Hadron Collider. The search is performed over the mass range 170 ≤ mX ≤ 1000 GeV and 15 ≤ mS ≤ 500 GeV. Parameterised neural networks are used to enhance the signal purity and to achieve continuous sensitivity in a domain of the (mX, mS) plane. No significant excess above the expected background is found and 95% CL upper limits are set on the cross section times branching ratio, ranging from 39 fb to 0.09 fb. The largest deviation from the background-only expectation occurs for (mX, mS) = (575, 200) GeV with a local (global) significance of 3.5 (2.0) standard deviations.
Supplementary document for Highly Sensitive Double D-shaped Channel Photonic Crystal Fiber based Plasmonic Refractive Index Sensor - 5723693.pdf
Creators: name: Isti, M. Ifaz Ahmad
name: Anik, M Hussayeen Khan
name: Nuzhat, Samiha
name: TALUKDER, RUBEL
name: SULTANA, SADIA
name: BISWAS, SHOVASIS KUMAR
name: Talukder, Hriteshwar
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Study on metal layer thickness, pitch and air hole diameter variation
Il trattamento del delirium nel paziente anziano ospedalizzato in un reparto di medicina. Una revisione della letteratura
Creators: name: Gaggini, Arianna
name: Frei, Giulia
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2022

description: Background Il delirium, anche chiamato stato confusionale acuto, è un disturbo dell’attenzione, dello stato cognitivo e del livello di coscienza. È caratterizzato da un’insorgenza acuta e da un andamento fluttuante della sintomatologia. Esistono tre tipologie di delirium: iperattivo, ipoattivo e misto. Lo stato confusionale acuto è una condizione complessa e comune che colpisce in media il 10-31% dei pazienti anziani. Questo disturbo ha un’eziologia definita multifattoriale, ed è associato a scarsi outcome e maggiori costi sanitari. Spesso il delirium non viene diagnosticato in tempo e viene mal interpretato, ciò porta a maggiori complicazioni per il paziente. Il trattamento consiste nell’individuazione della causa e nel trattamento della sintomatologia. Molti sono gli interventi non farmacologici che si possono applicare preventivamente e in fase di cura. Obiettivo L’obiettivo di questo lavoro di tesi è quello di individuare gli interventi efficaci ed il giusto trattamento per lo stato confusionale acuto nei pazienti anziani ospedalizzati; mediante l’individuazione delle più recenti evidenze scientifiche. Attraverso questo lavoro di tesi, siamo sicure che l’identificazione degli interventi ci possa trasmettere conoscenze da mettere in atto nella pratica professionale. Metodologia Per questo lavoro di tesi è stato utilizzato il metodo della revisione sistematica della letteratura. La ricerca è stata effettuata grazie all’utilizzo delle banche dati: PubMed Central Journals; Europe PMC; Cinhal e AHFS Consumer Medicazion Index. I nostri criteri di inclusione sono: età maggiore o uguale a 65 anni; trattamenti farmacologici e non farmacologici; reparto di medicina; articoli pubblicati negli ultimi otto anni. Risultati Da questo lavoro di revisione della letteratura emerge che gli interventi multicomponenti hanno avuto una buona efficacia preventiva e di trattamento nel paziente anziano con delirium. Dagli articoli analizzati, gli interventi non farmacologici sono stati diretti verso la persona, o verso l’ambiente che la circonda. Conclusioni Molti articoli di ricerca hanno dimostrato come sia possibile diminuire il rischio della presenza di delirium svolgendo interventi preventivi. Dall’analisi dei risultati si è riscontrata però la necessità di ampliare gli studi riguardo il trattamento del delirium, in quanto si sono evidenziate problematiche legate alla ridotta casistica che ha partecipato agli studi.
Dysschema arema
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Dysschema
Dysschema arema

description: Dysschema arema (Boisduval, 1870)
Thebrone arema Boisduval, 1870: 85.
TYPE LOCALITY. — Nicaragua; Venezuela.
TYPE SPECIMENS. — Described from 2 syntypes (BMNH; one male specimen from Colomb[ia] (!) labeled TYPE).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 473, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Design and Bench Validation of a Mechanical Intravaginal Dynamometer Mechanism
Creators: name: Brennan, Ana Bryn
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2022
Subjects: pelvic floor
biomechanics
dynamometer
muscle strength
mechanism

description: Strength and tone of the pelvic floor muscles are thought to play an important role in pelvic floor disorders, and are key outcomes monitored in pelvic floor rehabilitation, yet the standard approach to measuring these outcomes is through subjective assessment using manual palpation. While intravaginal dynamometers (IVD) have been designed to measure these characteristics in research settings, most are not sufficient to withstand the rigors of clinical use. This work presents the bench validation and subsequent updated design of a new mechanical constant speed mechanism for future inclusion in an IVD. Opening speeds of the original mechanism were validated with and without external loading using video analysis. The bench validation showed that the speed of arm opening was lower than the ranges specified for clinical use and was influenced by external loading. The mechanism was updated, and the bench test was repeated. The updated mechanism was found to provide output speeds that are within the ranges required clinically and were minimally impacted by external loading. The next step of this work is to reduce the size of the mechanism and improve output speeds to allow it to be assembled into a clinical prototype IVD.
The relationship between polygenic risk scores and cognition in Schizophrenia
Creators: name: Walters J.T.R.
name: Loohuis L.M.O
name: Morris D.W
name: Holmans P
name: Richards A.L
name: Espeseth T
name: Konte B
name: Owen M.J.
name: Ophoff R.A
name: Rutten B.P.F.
name: Pardiñas A.F
name: Ferraro L
name: Bloklande G.A.M.
name: Degenhardt F
name: Donohoe G.
name: Sundet K.
name: Melle I
name: Nyman H
name: Cosgrove D
name: Frizzati A
name: Quattrone D.
name: Giegling I
name: Legge S.E
name: Andreassen O.A
name: Jönsson E.G
name: Van Ose J
name: O'Donovan M.C.
name: Sullivan P.F.
name: Streit F.
name: Rujescu D.
name: Tansey K.E
name: Savage J.E
name: Blokland G.A.M
name: Wagner M.
name: Van Os J.
name: Corvin A
name: Petryshen T.L.
name: Escott-Price V.
name: Morgan C
name: Gayer-Anderson C
name: Hartmann A.M
name: Djurovic S
name: Lennertz L
name: Van Haren N.E
name: Rietschel M.
name: Van Osk J.
name: Agartz I
name: Lynham A.J
name: Hubert J.J
name: Strohmaier J.
name: Murray R.M
Publisher: name: Oxford University Press
Year: 2020

description: Background: Cognitive impairment is a clinically important feature of schizophrenia. Polygenic risk score (PRS) methods have demonstrated genetic overlap between schizophrenia, bipolar disorder (BD), major depressive disorder (MDD), educational attainment (EA), and IQ, but very few studies have examined associations between these PRS and cognitive phenotypes within schizophrenia cases. Methods: We combined genetic and cognitive data in 3034 schizophrenia cases from 11 samples using the general intelligence factor g as the primary measure of cognition. We used linear regression to examine the association between cognition and PRS for EA, IQ, schizophrenia, BD, and MDD. The results were then meta-analyzed across all samples. A genome-wide association studies (GWAS) of cognition was conducted in schizophrenia cases. Results: PRS for both population IQ (P = 4.39 × 10-28) and EA (P = 1.27 × 10-26) were positively correlated with cognition in those with schizophrenia. In contrast, there was no association between cognition in schizophrenia cases and PRS for schizophrenia (P = .39), BD (P = .51), or MDD (P = .49). No individual variant approached genome-wide significance in the GWAS. Conclusions: Cognition in schizophrenia cases is more strongly associated with PRS that index cognitive traits in the general population than PRS for neuropsychiatric disorders. This suggests the mechanisms of cognitive variation within schizophrenia are at least partly independent from those that predispose to schizophrenia diagnosis itself. Our findings indicate that this cognitive variation arises at least in part due to genetic factors shared with cognitive performance in populations and is not solely due to illness or treatment-related factors, although our findings are consistent with important contributions from these factors.
Pharmacological Regulation of Ischemia-Activated Pericyte Reprogramming and Differentiation for Post-Stroke Regeneration and Recovery
Creators: name: Lui, Margarita
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2022
Subjects: Stroke
Regeneration
Cellular reprogramming
Pericytes

description: Direct in vivo cellular reprogramming offers the potential for local neural replacement to promote post-stroke neural regeneration and recovery. Pericytes are perivascular cells involved in blood-brain barrier maintenance under physiological conditions but are reprogrammed into multipotent induced neural progenitor cells (i-NPCs) in response to ischemia. The atypical protein kinase C (aPKC)-CREB binding protein (CBP) pathway regulates ischemia-activated pericyte (a-pericyte) reprogramming and neuronal differentiation. Our previous work showed that the pathway inhibitor compound C (CpdC) facilitated a- pericyte reprogramming into i-NPCs in culture, and that monoacylglycerol lipase (Mgll) inhibitor JZL184 was able to promote NPC differentiation to generate newborn neurons by mimicking pathway activation. In this regard, we propose to use acute CpdC treatment followed by chronic JZL184 treatment to enhance reprogramming of a-pericytes into i-NPCs and subsequently promote their neuronal differentiation, ultimately improving post-stroke functional recovery. Using the endothelin-1 (ET-1)/L-NAME ischemic stroke model in a pericyte lineage tracing transgenic mouse line, I characterized the ability of a-pericytes in the ischemic lesion site to generate neural (i-NPC, newborn neurons) and non-neural (microglia and fibroblasts) cell types. The CpdC+JZL184 treatment had early effects on enhancing a- pericyte reprogramming efficiency to produce i-NPCs at 7 days post-stroke and promoting their differentiation to generate neuroblasts at 14 days post-stroke. However, it did not affect stroke volume and produced minimal alterations to the pattern of post-stroke motor function recovery. Interestingly, I discovered a novel role of tamoxifen treatment prior to stroke in regulating reprogramming of a-pericytes and efficacy of compound C treatment. These studies inform the necessity of optimization of drug delivery for better control over the timing and duration to directly target in vivo i-NPC reprogramming and reveal a novel pharmacological paradigm to control the aPKC-CBP pathway.
The role of healthcare providers in HPV vaccination programs – A meeting report
Creators: name: Maltezou H.C
name: Van Damme P
name: Arbyn M
name: Hanley S
name: Yarwood J
name: Muñoz N
name: Pattyn J
name: Brewer N.T
name: Baay M
name: Kojouharova M
name: Bosch F.X
name: Cameron R
name: Franco E.L
name: Bonanni P
name: Karafillakis E
name: Vorsters A
Publisher: name: Elsevier B.V.
Year: 2019

description: The Human Papillomavirus (HPV) Prevention and Control Board convened a meeting in Bucharest, Romania (May 2018), to discuss the role of healthcare providers (HCPs) in prevention programs, with a focus on HPV vaccination and cervical cancer screening. International and local experts discussed the role that HCPs can play to increase the uptake of HPV vaccine and screening. Experts recommended: 1) increasing HCP norms of getting vaccinated; 2) training providers to make effective recommendations; 3) making culturally appropriate materials available, in local languages; and 4) centralizing and coordinating education and information material, to direct both HCPs and the general public to the best material available.
Interventi infermieristici per la promozione della salute e prevenzione delle malattie cardiovascolari con approccio di una differenziazione di genere
Creators: name: Bujas, Mattia
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2022

description: Background Le malattie cardiovascolari, seppur in ambito medico e nell’assistenza infermieristica vi siano continui progressi, rimangono la prima causa di morte nel mondo in generale. Secondo l’OMS, ogni anno muoiono più persone a causa di patologie cardiovascolari che per qualsiasi altra causa. Si è stimato che nel 2016 siano morte 17,9 milioni di individui a causa delle malattie cardiovascolari, pari al 31% di tutti i decessi globali. Le malattie cardiovascolari sono, erroneamente, classificate con prevalenza maschile. Le statistiche mostrano che il 54% delle donne residenti nel continente europeo decede secondariamente ad una patologia cardiovascolare. La medicina di genere mira a garantire l’adeguatezza diagnostico-terapeutica rendendo possibili trattamenti che siano adattati al singolo individuo. Obiettivo Lo scopo di questa tesi è quello di definire, tramite letteratura e articoli scientifici, cos’é la medicina di genere, il suo ruolo all’interno della società e gli sviluppi avvenuti. Un ulteriore obiettivo consiste nell’esporre tramite revisione della letteratura gli interventi infermieristici volti alla promozione della salute e alla prevenzione delle malattie cardiovascolari, attuando una differenziazione di genere, mirando così ad un miglioramento della qualità di vita sia per gli uomini che per le donne. Metodologia La metodologia adottata è la revisione della letteratura scientifica relativa al ruolo infermieristico in relazione alla promozione della salute e alla prevenzione delle malattie cardiovascolari tramite un approccio differenziato di genere. Per la ricerca degli articoli scientifici si è usufruito prevalentemente della banca dati Pubmed tramite le stringhe di ricerca sviluppate. Per il background, oltre alle banche dati, sono stati utilizzati siti web e libri di testo. Risultati Il lavoro di tesi ha potuto evidenziare come gli interventi infermieristici, volti alla riduzione dei rischi cardiovascolari, nelle donne - ma anche negli uomini – siano risultati efficaci negli studi esposti. Gli studi si sono concentrati sul miglioramento della qualità di vita mediante interventi di prevenzione sui fattori di rischio, come il consumo di tabacco per esempio oppure interventi di promozione come l’attività fisica. Conclusioni Dalle ricerche è emerso che esistono delle differenze di genere in medicina; fortunatamente gli studi legati a questa branca della medicina stanno prendendo sempre più piede nella comunità scientifica. Viene esposta anche l’importanza dell’infermiere nella prevenzione e promozione della salute nella medicina di genere e l’importanza di attuare nella pratica professionale un approccio di genere con il paziente.
CARMOLIT 2015 LEG2 / SIMEO-02 cruise,Thalia R/V
Creators: name: QUEMENER Loïc
Publisher: name: Sismer
Year: 2015

description: Relevage de la bouée MOLIT mouillée en février en baie de Vilaine. Cette bouée est sortie de l'eau pour son carénage annuel. Le projet de rattachement est "Système de mesure". Relevage de la bouée SIMEO.
Assistenza infermieristica al paziente tracheostomizzato: gestione della tracheostomia ed educazione al caregiver familiare. Revisione della letteratura
Creators: name: Luciani, Alessia
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2022

description: Background L’assistenza al paziente con tracheostomia richiede delle competenze infermieristiche per la sua corretta gestione. Dopo l’intervento chirurgico la durata della degenza ospedaliera è breve e la persona viene dimessa al domicilio incerta sulle implicazioni per il postoperatorio. Nei primi giorni, l’individuo si renderà consapevole che i propri ritmi di vita saranno cambiati e assieme al proprio caregiver saranno circondati da insicurezze e perplessità. È essenziale, quindi, che il processo di apprendimento ed elaborazione inizi nella fase preoperatoria e che il paziente torni a casa autonomo nell’autocura, sicuro e fiducioso. Obiettivi Lo scopo del seguente Lavoro di Tesi è riconoscere i bisogni educativi di questa tipologia di utenza, identificare gli interventi di cura che l’infermiere deve attuare durante la degenza ospedaliera e indagare se l’educazione terapeutica fornita dal personale curante implichi un miglioramento sulla qualità di vita dei pazienti. Metodologia La metodologia impiegata per redigere il presente scritto è la revisione di letteratura. La ricerca degli articoli è stata eseguita consultando alcune banche dati, quali CINAHL (EBSCO), PubMed, Cochrane Library e Google scholar. Risultati La ricerca ha elaborato un totale di 327 studi, 6 di questi sono stati inclusi per rispondere alla domanda di ricerca. Gli articoli scelti sono concordi e dimostrano che l’implementazione di interventi educativi per il paziente e il suo caregivers garantiscono degli esiti favorevoli sulla loro qualità di vita. Conclusioni Il presente LT conferma che i programmi educativi in pazienti con tracheostomia possono favorire l’apprendimento di nuove competenze e abilità, promuovere l’autocura e ridurre l’ansia per i caregivers. Keywords Tracheostomy patient, caregiver, effect, education program, care, home care services, evaluate, tracheostomy, multimedia education, quality of life, educational need, lifestyle.
The role of puberty on physical and brain development: A longitudinal study in male Rhesus Macaques
Creators: name: Fair, D
name: Raper, J
name: Kovacs-Balint, Z.A
name: Ethun, K.F
name: Sanchez, M.M
name: Kettimuthu, K.P
name: Earl, E
name: Feczko, E
name: Richardson, R
name: Gopakumar, A
name: Higgins, M
name: Styner, M.
name: Li, L
name: Bachevalier, J
Publisher: name: Elsevier Ltd
Year: 2023

description: This study examined the role of male pubertal maturation on physical growth and development of neurocircuits that regulate stress, emotional and cognitive control using a translational nonhuman primate model. We collected longitudinal data from male macaques between pre- and peri-puberty, including measures of physical growth, pubertal maturation (testicular volume, blood testosterone -T- concentrations) and brain structural and resting-state functional MRI scans to examine developmental changes in amygdala (AMY), hippocampus (HIPPO), prefrontal cortex (PFC), as well as functional connectivity (FC) between those regions. Physical growth and pubertal measures increased from pre- to peri-puberty. The indexes of pubertal maturation -testicular size and T- were correlated at peri-puberty, but not at pre-puberty (23 months). Our findings also showed ICV, AMY, HIPPO and total PFC volumetric growth, but with region-specific changes in PFC. Surprisingly, FC in these neural circuits only showed developmental changes from pre- to peri-puberty for HIPPO-orbitofrontal FC. Finally, testicular size was a better predictor of brain structural maturation than T levels -suggesting gonadal hormones-independent mechanisms-, whereas T was a strong predictor of functional connectivity development. We expect that these neural circuits will show more drastic pubertal-dependent maturation, including stronger associations with pubertal measures later, during and after male puberty.
title: Efficacy of Emergency Penetrating Keratoplasty with Cryopreserved Human Donor Corneas
Creators: name: Bidzan, Malik
name: Eter, Nicole
name: Uhlig, Constantin
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2024
Subjects: subject: 610 Medicine and health

description: Introduction: To investigate the long-term outcomes of emergency penetrating keratoplasty using cryopreserved human donor corneas in the management of actual or imminent corneal perforation.
Methods: A retrospective analysis was performed of the treatment efficacy of emergency penetrating keratoplasty using a cryopreserved human donor cornea, in 14 eyes of 14 patients with corneal ulcers of different etiology. For comparison, the medical histories of 14 patients who had undergone penetrating keratoplasty with the same indication, but received a regularly processed human corneal graft, were retrospectively analyzed. In both groups, the primary endpoint for graft failure was repeat surgery, defined as the necessity for amniotic membrane transplantation, conjunctival flap, or repeat penetrating keratoplasty, during a follow-up time of maximally 12 months. Results: The difference in the need for repeated surgeries between the cryopreserved human donor cornea group and cultivated tissue graft group was not statistically significant (p = 0.835). Specifically, repeat complex surgery of any kind within 6 months was necessary in 50% of the cryopreserved cornea group and in 57.1% of the control group, with no further surgical interventions during the remainder of the follow-up period. However, repeat penetrating keratoplasty occurred more frequently in the cryopreserved cornea group (n = 5) than in the control group (n = 1) during the first 12 months after treatment (p = 0.048).
Conclusion: Cryopreserved corneas appear to be a viable option for promptly addressing emergencies and stabilizing the corneal situation, providing a faster solution compared to waiting for fresh tissue availability. However, repeat penetrating keratoplasty is more frequent when cryopreserved human donor corneas are used. Cryopreserved human donor corneas may be useful if surgical treatment is urgent and alternative options, such as tissue use, a conjunctival flap, or multilayer amniotic membrane transplantation, are not available.
description: Finanziert durch den Open-Access-Publikationsfonds der Universität Münster.
The silent and dangerous inequity around access to COVID-19 testing: A call to action
Creators: name: Wilder-Smith A
name: Bottazzi M.E
name: Strub-Wourgaft N
name: Amor Y.B
name: Kim J.H
name: Gursel M
name: Batista C
name: Lall B
name: Hassanain M
name: Kaslow D
name: Sow S.O
name: Loveday S.-J
name: Ergonul O
name: Yadav P
name: Hotez P
name: Naniche D
name: Figueroa J.P
name: Sheahan T
name: Kang G
name: Shoham S
name: Hannay E
name: Larson H
Publisher: name: Elsevier Ltd
Year: 2022

description: The COVID-19 pandemic is a public health crisis of unprecedented proportions. Despite unparalleled rates of vaccination and mass testing in certain parts of the world, the virus rages on. Since SARS-CoV-2, the virus that causes COVID-19, was first isolated in Wuhan, China, on 7 January 2020, more than 243 million cases and 4.9 million deaths have been reported worldwide at the time of writing.
Dysschema thetis
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Dysschema
Dysschema thetis

description: Dysschema thetis (Klug, 1836)
Euprepia thetis Klug, 1836: 5.
Daritis howardi Edwards, 1887a: 165. — Type locality: [USA], N[ew] Mexico. — Type specimens: Described from 3 syntypes (AMNH; one male syntype labeled TYPE no. 8238).
TYPE LOCALITY. — Mexico.
TYPE SPECIMEN. — Lectotype male designated by Becker (2013: 60) (ZMHB).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 473, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
The simplicit1 study: A randomized, double-blind, placebo-controlled phase 1b/2 adaptive study of ttp399, a hepatoselective glucokinase activator, for adjunctive treatment of type 1 diabetes
Creators: name: Dvergsten C
name: Freeman J.L.R
name: Dunn I
name: Valcarce C
name: Klein K.R
name: Buse J.B
name: Kirkman M.S
Publisher: name: American Diabetes Association Inc.
Year: 2021

description: OBJECTIVE Despite advances in exogenous insulin therapy, many patients with type 1 diabetes do not achieve acceptable glycemic control and remain at risk for ketosis and insulin-induced hypoglycemia. We conducted a randomized controlled trial to determine whether TTP399, a novel hepatoselective glucokinase activator, improved glycemic control in people with type 1 diabetes without increasing hypoglycemia or ketosis. RESEARCH DESIGN AND METHODS SimpliciT1 was a phase 1b/2 adaptive study. Phase 2 activities were conducted in two parts. Part 1 randomly assigned 20 participants using continuous glucose monitors and continuous subcutaneous insulin infusion (CSII). Part 2 randomly assigned 85 participants receiving multiple daily injections of insulin or CSII. In both parts 1 and 2, participants were randomly assigned to 800 mg TTP399 or matched placebo (fully blinded) and treated for 12 weeks. The primary end point was change in HbA1c from baseline to week 12. RESULTS The difference in change in HbA1c from baseline to week 12 between TTP399 and placebo was-0.7% (95% CI-1.3,-0.07) in part 1 and-0.21% (95% CI-0.39,-0.04) in part 2. Despite a greater decrease in HbA1c with TTP399, the frequency of severe or symptomatic hypoglycemia decreased by 40% relative to placebo in part 2. In both parts 1 and 2, plasma β-hydroxybutyrate and urinary ketones were lower during treatment with TTP399 than placebo. CONCLUSIONS TTP399 lowers HbA1c and reduces hypoglycemia without increasing the risk of ketosis and should be further evaluated as an adjunctive therapy for the treatment of type 1 diabetes.
Dryopteris aizoides L.
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S. aizoides L. Cat. 153 und 426. Obere Höhengrenze festzustellen. Die Angabe des Cat. (3100m) und diejenige BRAUN-BLANQUET'S in der Flora von Hegi,l. c.,S.596 (3030m) beziehensich auf den Fundort bei der ehemaligen Vincenthütte,italienische Seite des Monte Rosa (vgl. Schlagintweit Lit. 1854,S.228).- Abwärtsbis390m:bei St-Gingolph (J.). Var. crocea Gaudin - 4: Rhonegletscher (P.). Var. atropurpurea Sternb. (var. atrorubens [Bertol.] Engler) - l: Salanfe (J.). - 2: Lac de Fully (Paiche).- 3:Valsorey (Guyot); Mauvoisin(Zahn). - 3a: Gondo, ob den Goldminen gegen die italienische Grenze (Frauenfelder). Var. vallesiaca Briq. - 3: Pierre ä Voir (Chenevard).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Modelling the Repair of Carbon-Centered Protein Radicals by Phenolic Antioxidants
Creators: name: Walton-Raaby, Max
name: Floen, Tyler
name: Mora-Diez, Nelaine
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2024

description: Oxidative stress is a biological process that has been linked to many diseases, hence understanding how to prevent and repair it is essential to medicine. The thermodynamics and kinetics of the repair reactions of radically damaged leucine (a lateral chain in a simplified protein environment) by twenty phenolic antioxidants are studied at the M06-2X(SMD)/6-31++G(d,p) level of theory in water and pentyl ethanoate. The two repair mechanisms modelled are formal-hydrogen atom transfer (f-HAT) and single electron transfer (SET). Although all f-HAT reactions are thermodynamically favourable, only one of the phenols produced rate constants in the diffusion limit, exhibiting biological relevance. SET is not suspected to be an important repair pathway for the phenols studied. We show that the Bell–Evans–Polanyi principle, which relates thermodynamics and kinetics properties for a reaction, breaks down when comparing between the solvents, protein repair sites, and the phenolic antioxidants. While thermodynamic data can be used as valuable screening tools, the kinetic calculation of rate constants in solution is crucial for enhancing the biological relevance of theoretical studies.
The state of the science in psychiatric genomics
Creators: name: Kendler K.S
name: Sullivan P.F
Publisher: name: Cambridge University Press
Year: 2021

description: The awfulness of 2020 has been described with eloquence and detail by many authors around the world. Put simply, at nearly every turn, events went in the wrong direction. So, it is nice to report a 2020 project that went well – in fact, for a change, something that went wonderfully better than expected.
MPEC 2024-P93 : DAILY ORBIT UPDATE (2024 August 7)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
Creators: name: Leontovich A.M
name: Poon L.L.M
name: Lauber C
name: Baker S.C
name: Perlman S
name: Gorbalenya A.E
name: Sola I
name: Baric R.S
name: Drosten C
name: Ziebuhr J
name: Haagmans B.L
name: Samborskiy D.V
name: Sidorov I.A
name: Penzar D
name: Gulyaeva A.A
name: de Groot R.J
name: Neuman B.W
Publisher: name: Nature Research
Year: 2020

description: The present outbreak of a coronavirus-associated acute respiratory disease called coronavirus disease 19 (COVID-19) is the third documented spillover of an animal coronavirus to humans in only two decades that has resulted in a major epidemic. The Coronaviridae Study Group (CSG) of the International Committee on Taxonomy of Viruses, which is responsible for developing the classification of viruses and taxon nomenclature of the family Coronaviridae, has assessed the placement of the human pathogen, tentatively named 2019-nCoV, within the Coronaviridae. Based on phylogeny, taxonomy and established practice, the CSG recognizes this virus as forming a sister clade to the prototype human and bat severe acute respiratory syndrome coronaviruses (SARS-CoVs) of the species Severe acute respiratory syndrome-related coronavirus, and designates it as SARS-CoV-2. In order to facilitate communication, the CSG proposes to use the following naming convention for individual isolates: SARSCoV-2/host/location/isolate/date. While the full spectrum of clinical manifestations associated with SARS-CoV-2 infections in humans remains to be determined, the independent zoonotic transmission of SARS-CoV and SARS-CoV-2 highlights the need for studying viruses at the species level to complement research focused on individual pathogenic viruses of immediate significance. This will improve our understanding of virus–host interactions in an ever-changing environment and enhance our preparedness for future outbreaks.
I benefici della risata per l’anziano ricoverato in casa per anziani o in ospedale e per gli infermieri
Creators: name: Costa, Federica
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2018
Subjects: Case per anziani
anziani
umorismo

description: Background L’anziano ricoverato in casa per anziani, al centro diurno o in ospedale subisce dei cambiamenti e spesso hanno anche delle patologie che possono creare delle disfunzioni come ad esempio la perdita di memoria, che può creare in loro disorientamento. Noi sanitari possiamo aiutare i pazienti ricoverati ad avere una degenza migliore utilizzando l’umorismo, così da prestare cure migliori ed avere un legame più veritiero tra curante e paziente. Per poter comprendere al meglio i benefici della risata a livello psichico e fisico bisogna partire da un’attenta analisi di ciò che invece comporta lo stress, in termini di malattie. Fondamentale nel lavoro socio sanitario individuare quando siamo a rischio di burnout, sindrome che può presentarsi come silente per poi creare seri problemi psicologici al lavoratore, oltre che portare il curante a dare delle cure di scarsa qualità. Obiettivi Lo scopo principale di questo lavoro è quello di comprendere quali siano i benefici della risata sull’organismo a livello fisico e psichico per poter, nel mio futuro professionale, aiutare me stessa come professionista e i miei colleghi ad evitare di cadere nella sindrome del burnout. Inoltre desidero utilizzare l’umorismo per sostenere al meglio i pazienti che curerò nella loro malattia, sperando di aiutarli ad avere una ripresa ottimale. Metodologia della ricerca Inizialmente mi sono focalizzata sulla teoria svolta negli anni scolastici e nei libri per poi ampliare la mia ricerca alle banche dati (PubMed, SAGE journal e EBSCO). In questo modo ho potuto ritrovare un riscontro tra la teoria ricercata e gli articoli scientifici in cui risultavano gli effettivi risultati di studi eseguiti da esperti negli anni. Risultati I risultati dimostrano che l’umorismo è in grado di diminuire la percezione del dolore, migliorare la respirazione, diminuire la pressione arteriosa, l’ansia e le tensioni sociali . Conclusioni L’infermiera dovrebbe, quando possibile, utilizzare l’umorismo anche nei centri di cura, in quanto la risata è spesso vissuta come un tabù, ma in realtà è in grado di provocare molti benefici in sé stessi, negli altri e nelle relazioni sociali tra più individui