cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Estimation of Monotone Treatment Effects in Network Experiments
Creators: name: Choi, David
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy

description: Randomized experiments on social networks pose statistical challenges, due to the possibility of interference between units. We propose new methods for finding confidence intervals on the attributable treatment effect in such settings. The methods do not require partial interference, but instead require an identifying assumption that is similar to requiring nonnegative treatment effects. Network or spatial information can be used to customize the test statistic; in principle, this can increase power without making assumptions on the data-generating process. Supplementary materials for this article are available online.
O'ZBEKISTONDA XOTIN-QIZLARNING IT SAVODXONLIGINI RIVOJLANTIRISHDA ERISHILGAN YUTUQLAR VA MAVJUD MUAMMOLAR
Creators: name: Shermanova, F.D.
Publisher: name: Zenodo
Year: 2024

description: Mazkur maqolada jamiyatimizda ayollarning texnika sohasida yetakchi o‘rinlarni egallashiga qaratilgan tizimli islohotlar yoritilgan. Hozirda shiddat bilan rivojlanib borayotgan raqamli  texnologiyalar davrida ayol-qizlarning о‘z qobiliyat va imkoniyatlarini rо‘yobga chiqarish uchun shart-sharoit yaratish, har tomonlama qо‘llab-quvvatlash, ularga berilayotgan imkoniyatlar va qiynayotgan masalalar hamda qator takliflar keltirib o’tilgan.
Estimation of Monotone Treatment Effects in Network Experiments
Creators: name: Choi, David
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: Randomized experiments on social networks pose statistical challenges, due to the possibility of interference between units. We propose new methods for finding confidence intervals on the attributable treatment effect in such settings. The methods do not require partial interference, but instead require an identifying assumption that is similar to requiring nonnegative treatment effects. Network or spatial information can be used to customize the test statistic; in principle, this can increase power without making assumptions on the data generating process.
Simultaneous depletion of albumin and immunoglobulin G by using twin affinity magnetic nanotraps
Creators: name: Büyüktiryaki, Sibel
name: Uzun, Lokman
name: Denizli, Adil
name: Rıdvan Say
name: Ersöz, Arzu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: For biomarker discovery, simultaneous removal of albumin and immunoglobulin G (IgG) become more important for both concentrating other species including potential biomarkers and getting rid of their masking effect. In this study, we have proposed a covalent and photosensitive cross-linking conjugation of the biomolecules on nanostructures for the depletion of target proteins from aqueous solution and serum. The effect of concentration, pH, temperature and ionic strength on the adsorption of twin affinity nanotraps based on Cibacron Blue F3GA and Protein A were investigated. The efficiency of albumin and IgG depletion from human serum was performed using sodium dodecylsulfate–polyacrylamide gel electrophoresis.
Simultaneous Depletion of Albumin and Immunoglobulin G by Using Twin Affinity Magnetic Nanotraps
Creators: name: Büyüktiryaki, Sibel
name: Uzun, Lokman
name: Denizli, Adil
name: R. Say
name: Ersöz, Arzu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: For biomarker discovery, simultaneous removal of albumin and immunoglobulin G (IgG) become more important for both concentrating other species including potential biomarkers and getting rid of their masking effect. In this study, we have proposed a covalent and photosensitive crosslinking conjugation of the biomolecules on nano-structures for the depletion of target proteins from aqueous solution and serum. The effect of concentration, pH, temperature and ionic strength on the adsorption of twin affinity nanotraps based on Cibacron Blue F3GA (CB) and Protein A (Pro A) were investigated. The efficiency of albumin and IgG depletion from human serum was performed using sodium dodecylsulfate-polyacrylamide gel electrophoresis (SDS-PAGE).
Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling
Creators: name: Hyowon Choi
name: Merceron, Christophe
name: Mangiavini, Laura
name: Seifert, Erin L.
name: Schipani, Ernestina
name: Shapiro, Irving M.
name: Makarand V. Risbud
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Developmental Biology
subject: Cancer

description: Nucleus pulposus (NP) cells reside in the avascular and hypoxic microenvironment of intervertebral discs. Importantly, many activities related to survival and function of NP cells are controlled by the HIF-family of transcription factors. We hypothesize that NP cells adapt to their hypoxic niche through modulation of macroautophagy/autophagy. In various cell types, hypoxia induces autophagy in a HIF1A-dependent fashion; however, little is known about hypoxic regulation of autophagy in NP cells. Hypoxia increases the number of autophagosomes as seen by TEM analysis and LC3-positive puncta in NP cells. Hypoxic induction of autophagy was also demonstrated by a significantly higher number of autophagosomes and smaller change in autolysosomes in NP cells expressing tandem-mCherry-EGFP-LC3B. Increased LC3-II levels were not accompanied by a concomitant increase in BECN1 or the ATG12–ATG5 complex. In addition, ULK1 phosphorylation at Ser757 and Ser777 responsive to MTOR and AMPK, respectively, was not affected in hypoxia. Interestingly, when MTOR activity was inhibited by rapamycin or Torin1, LC3-II levels did not change, suggesting a novel MTOR-independent regulation. Noteworthy, while silencing of HIF1A affected hypoxic induction of BNIP3, it did not affect LC3-II levels, indicating hypoxia-induced autophagy is HIF1-independent. Importantly, there was no change in the number of LC3-positive autophagosomes in NP-specific Hif1a null mice. Finally, inhibition of autophagic flux did not affect the glycolytic metabolism of NP cells, suggesting a possible nonmetabolic role of autophagy. Taken together, our study for the first time shows that NP cells regulate autophagy in a noncanonical fashion independent of MTOR and HIF1A signaling.
title: 01_1078
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
The Efect of Conservation Payments on Farmer Adoption Varies Across Conservation Practices
Creators: name: Claassen, Roger
name: Smith, David
name: Claassen, Roger
name: Smith, David
Publisher: name: Unknown
Year: 2018
Subjects: subject: Agricultural and Food Policy
subject: Environmental Economics and Policy
subject: Farm Management
subject: Institutional and Behavioral Economics
subject: Land Economics/Use
subject: conservation programs
subject: environmental
subject: conservation
subject: agricultural
subject: tillage
subject: additionality

description: USDA conservation programs provide technical assistance to help farmers conserve resources and improve environmental quality. Conservation practices supported by payments deliver “additional” conservation or environmental improvement if the practice would not have been adopted without the payment. The extent of additionality varies widely across conservation practices.
Fast Neutron Dosimetry Employing Soft Error Detection in Dynamic Random Access Memories
Creators: name: Brooks, Michael David
Publisher: name: London South Bank University
Year: 1995

description: During the mid 1970s it was found that the logic state of integrated circuits could be altered by the passage through them of ionising particles. The aim of this study was to use this phenomenon in dynamic random access memory (DRAM) chips, where it is known as soft error production, to detect neutrons and thus provide a means of neutron dosimetry. 
The phenomenon is described, together with metal-oxide- Silicon (MOS) device operation, to show how soft errors can occur in MOS based DRAMs. The interactions of neutrons and protons in materials of interest are described, together with the current state of neutron dosimetric methods. 
The experimental work involving a Van de Graaff accelerator and Californium-252 isotopic neutron sources together with various polyethylene radiators is described. An attempt was made to model the phenomena occurring within the radiators and DRAM using Monte Carlo methods. Several approaches were used to describe the chord length distribution within the sensitive volume. The modelling results are described and the FORTRAN programs developed are given. 
It was found that detectors could be constructed with a sensitivity range of 70 to 2.7 mSv per soft error for the Van de Graaff source and between 2.2 and 0.8 Sv per error for the californium source. These results were within the range obtained from the modelling work.
Arbuscular mycorrhizal fungal community of wheat under long-term mineral and organic amendments in semi-arid Mediterranean Turkey
Creators: name: Buto, Takuya
name: Suzuki, Kazuki
name: Kaidzu, Tomoyuki
name: Taishi Narisawa
name: Oguz Can Turgay
name: Ortas, Ibrahim
name: Harada, Naoki
name: Nonaka, Masanori
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: Plant Biology

description: A minimal amount of information is currently available concerning arbuscular mycorrhizal (AM) fungal associations with crops in semi-arid zones on Leptosols in Turkey. Therefore, using molecular ecological techniques, we studied the effects of different management practices (without fertilization, chemical fertilization, farmyard manure, and plant compost amendments) on AM fungal communities associated with wheat roots. Experiments were conducted in a field established in 1996 in southern Mediterranean Turkey where soil productivity is low owing to unfavorable climatic effects and soil characteristics. We determined 201 partial sequences of AM fungal nuclear ribosomal large subunit genes. The higher AM fungal richness was found in the control treatment without fertilization and plant compost treatments compared with the chemical fertilization and farmyard manure treatments. Clones related to Rhizophagus were found in all treatments and accounted for 37% of the total AM fungal clones, whereas those of Funneliformis were dominant under chemical fertilization. Redundancy analysis based on the frequency of operational taxonomic units revealed that AM fungal communities were divided into three groups, namely, the control treatment, the chemical fertilization treatment, and the organic treatments (farmyard manure and plant compost treatments). Although different organic amendments supported relatively similar AM fungal communities, plant compost induced higher AM fungal richness than farmyard manure fertilization.
Visible-light-mediated facile synthesis of disulfides using reusable TiO2/MoS2 nanocomposite photocatalyst
Creators: name: Wenjie Liu
name: Cancan Wang
name: Yibo Huang
name: Chen, Qun
name: Wang, Liang
name: Mingyang He
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: A nontoxic and inexpensive TiO2/MoS2 nanocomposite was prepared and employed as an efficient photocatalyst for the synthesis of symmetrical disulfides under visible light irradiation at room temperature. Both aryl and alkyl thiols survived the reaction conditions, affording the corresponding disulfides in good to excellent yields. The photocatalyst could be easily recovered by simple centrifugation and filtration and reused several times without significant loss in its activity.
Visible-Light-mediated the Facile Synthesis of Disulfides Using Reusable TiO2/MoS2 Nanocomposite Photocatalyst
Creators: name: Wenjie Liu
name: Cancan Wang
name: Yibo Huang
name: Chen, Qun
name: Wang, Liang
name: Mingyang He
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: A nontoxic and inexpensive TiO2/MoS2 nanocomposite was prepared and employed as an efficient photocatalyst for the synthesis of symmetrical disulfides under visible light irradiation at room temperature. Both aryl and alkyl thiols survived the reaction conditions, affording the corresponding disulfides in good to excellent yields. The photocatalyst could be easily recovered by simple centrifugation and filtration, and reused several times without significant loss in its activity.
Facile access to α-acyloxyamides via epoxide rearrangement/three-component domino reaction catalyzed by indium(III) chloride
Creators: name: Kadari Lingaswamy
name: Palakodety Radha Krishna
name: Y. Lakshmi Prapurna
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: A simple and efficient Passerini reaction of epoxides involving highly regioselective rearrangement of epoxide to aldehyde/three-component Passerini reaction catalyzed by indium(III) chloride is described. In the present protocol, epoxides served as wonderful substrates to furnish a library of α-acyloxyamides under mild reaction conditions in shorter reaction times and in good yields.
Facile Access to α -acyloxyamides via Epoxide Rearrangement/Three Component Domino Reaction Catalyzed by Indium(III) Chloride
Creators: name: Kadari Lingaswamy
name: Palakodety Radha Krishna
name: Y. Lakshmi Prapurna
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: A simple and efficient Passerini reaction of epoxides involving highly regioselective rearrangement of epoxide to aldehyde/three component Passerini reaction catalyzed by Indium(III) Chloride is described. In the present protocol, epoxides served as wonderful substrates to furnish a library of α -acyloxyamides under mild reaction conditions in shorter reaction times and in good yields.
title: Paleoclimates of Mi’kma’ki: a sclerochronological analysis of Crassostrea virginica from an archaeological context in Malpeque Bay, Prince Edward Island
Creators: name: MacKinnon, Megan
Publisher: name: Memorial University of Newfoundland
publisherIdentifier: https://ror.org/04haebc03
publisherIdentifierScheme: ROR
Year: 2024

description: Pituamkek (CdCw-5), situated on Hog Island, in the province of Prince Edward Island, lies within the territory of the Mi’kmaq Nation. This study focuses on traditional oyster harvesting of the Mi’kmaq from 643-184 cal. BP. Specifically, we investigated the seasonal timing of shellfish collection and paleo-temperature reconstruction at the archaeological site. Ten archaeological eastern oyster shells (Crassostrea virginica) along with with two live collected valves (September 2019) from the surrounding Malpeque Bay underwent high-resolution shell oxygen isotope (δ¹⁸O) analysis and 180 individual archaeological shell fragments were analysed for growth stage determination. The δ¹⁸O results showed a pattern of year-round collection with an emphasis on warm weather collection. Results from shell growth increment analysis suggest the oysters at this region show high levels of stress in response to the conditions of the ambient environment and low sea surface temperatures. Archaeological shells show a larger δ¹⁸Oshell range, possibly reflecting a greater sea surface temperature amplitude than modern shells (i.e. a difference of ~10.9℃; modern range: ~ -1.7℃ to 17.5℃; archaeological range: ∼0℃ to 10.8℃). Results are contextualised with previous studies of paleoenvironmental analysis using oysters from the Eastern Seaboard in the USA, while interpreting these new data in the context of Mi’kmaq occupation and landscape use.
Cu(I)-promoted one-pot click-SNAr reaction of nitrobenzaldehydes
Creators: name: Changhui Su
name: Zhiyuan Ding
name: Liu, Xia
name: Cui, Kai
name: Jiejie Ma
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Inorganic Chemistry
subject: Plant Biology

description: A series of 1,4-disubstituted 1,2,3-triazoles containing formyl was synthesized from a variety of readily available nitrobenzaldehydes and alkynes via a convenient one-pot, click-SNAr reaction with moderate to excellent yields. The reactions were easily carried out in hexamethyl phosphoramide in the absence of a base at 60 °C.
Progress webinar (April 2022) for the UKRI Net Zero Digital Research Infrastructure Scoping Project
Creators: name: Townsend, Poppy
name: Juckes, Martin
name: Pascoe, Charlotte
name: Cartmell, Katie
Publisher: name: Zenodo
Year: 2022

description: This webinar was presented on 12th April 2022 by team members of the UKRI Net Zero Digital Research Infrastructure Scoping Project. The recording can be viewed here: https://youtu.be/NpUAvLFgYOA
KORRUPSIYAGA QARSHI KURASHNING LOYIHA BOSHQARUVIDA IJTIMOIY TA'SIRINI BAHOLASH
Creators: name: Tulyaganov, Raimjan
Publisher: name: Zenodo
Year: 2025

description: Ushbu maqola korrupsiyaga qarshi kurashning loyiha boshqaruvidagi ijtimoiy ta'sirini baholash masalalari, xususan korrupsiyaning loyihalarga ta'siri, korrupsiyaga qarshi kurashning ijtimoiy ta'sirini baholashning asosiy ko'rsatkichlari, baholash usullari va baholashda yuzaga keladigan muammolar tahlil qilinadi.
Combined effects of hollow fiber fabrication conditions and casting mixture composition on the properties of polysulfone ultrafiltration membranes
Creators: name: Sengur-Tasdemir, Reyhan
name: Urper, Gulsum Melike
name: Turker Turken
name: Genceli, Esra A.
name: Tarabara, Volodymyr V.
name: Koyuncu, Ismail
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology
subject: Plant Biology
subject: FOS: Biological sciences

description: This study is focused on identifying the combined effects of fabrication conditions and casting mixture composition on the properties of hollow fiber (HF) membranes. Three variables evaluated are air gap (0 and 2.5 cm); coagulation bath temperature (25°C; 35°C; 45°C) and molecular weight of polyvinylpyrrolidone (MWPVP = 10; 40; 65; 360; 1000 kDa). Prepared HF membranes were characterized in terms of specific permeate flux; surface morphology, charge and hydrophilicity; bovine serum albumin (BSA) rejection, Young modulus, and resistance to fouling by BSA. We illustrate that both higher and higher MWPVP are required to achieve optimal membrane morphology and performance.
Ordonnance du conseil souverain, concernant l'examen à subir par les Auditeurs de la Gouvernance de Douay, pour recevoir & passer des actes en qualité de Notaires
Creators: name: Plouvain, Pierre-Antoine-Samuel-Joseph (1754-1832)
name: Six, Philippe-Josse-Auguste-Joseph (1732-1793)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: Justice royale
Auxiliaire de justice
Officier ministériel

description: Source: http://nordnum.univ-lille.fr/ark:/72505/a0115224001360im5Ol/from/a011522400136ypxWl2
description: Coverage: Parlement de Flandre
description: created: 22/06/2018
description: created: 14/02/1676
Einfluss von Online-Partizipation auf den Verschwörungsglauben
Creators: name: Mellies, Johanna
Publisher: name: Universität Hamburg
Year: 2024

description: Die Verbreitung von Verschwörungstheorien über soziale Medien nimmt zu, wobei Filterblasen und Echokammern als mögliche Faktoren identifiziert werden. Diese Studie analysiert die Auswirkungen verschiedener sozialer Medien auf die Ausprägung des Verschwörungsglaubens und untersucht Mechanismen, die zur Abschottung gegenüber unterschiedlichen Meinungen und zur Verstärkung der Polarisierung in der Gesellschaft beitragen.
title: 03_0416
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Selective partition of caffeine from coffee bean and guaraná seed extracts using alcohol–salt aqueous two-phase systems
Creators: name: Santos, Samuel B.
name: Reis, Igor A. O.
name: Silva, Camila P. C.
name: Andressa F. Campos
name: Ventura, Sónia P. M.
name: Cleide M. F. Soares
name: Lima, Álvaro S.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: This work proposes the application of flexible alcoholic aqueous two-phase systems to manipulate the partition of caffeine. An optimization study was performed the caffeine partitioning towards top phase (60.0 wt% 2-propanol + 20.0 wt% K3PO4 at 303 K – Kcaf = 3.4 and RT = 89.1%) and bottom phase (60.0 wt% methanol + 17.5 wt% K2HPO4/KH2PO4 at 278 K – Kcaf = 0.06 and RB = 81.1%). These processes were evaluated by applying them to real biomass as guaraná seeds (purification factor (PF) = 6.59-fold) and coffee beans (PF = 3.24-fold) for the 2-propanol and K2HPO4/KH2PO4 system.
The 2012-13 U.S. Drought Heightened Federal Disaster Assistance Payments for Livestock Producers
Creators: name: MacLachlan, Matthew
name: Sean E. Ramos,
name: Hungerford, Ashley
name: MacLachlan, Matthew
name: Sean E. Ramos,
name: Hungerford, Ashley
Publisher: name: Unknown
Year: 2018
Subjects: subject: Environmental Economics and Policy
subject: Livestock Production/Industries
subject: Livesock Forage Disaser Program (LFP)
subject: livestock producers
subject: feed costs
subject: drought
subject: wildfire

description: Disaster assistance under LFP provides eligible livestock producers with payments to partially cover additional monthly feed costs in the event of drought or wildfire. During the 2008-16 period, a historic drought (October 2011-13) contributed significantly to increased outlays.
Characterisation of aspartic protease activity from the scabies mite Sarcoptes scabiei
Creators: name: Mahmood, Wajahat
Publisher: name: Charles Darwin University
Year: 2011

description: Scabies is a skin disease caused by the ectoparasitic mite Sarcoptes scabiei. It affectsmillions globally and is endemic in many populations. Current research in scabies isaimed at improving methods of diagnosis, elucidating determinants of hostpreference by scabies mites, and investigating host-parasite interactions, emergingresistance and novel therapeutic targets for disease control, among others.This study was designed to investigate the role of the S. scabiei aspartic protease,designated SsAP, in the life cycle of and as a determinant of host specificity by theparasite, and to characterise the physiological and physiochemical properties of thispotential drug target. The expression and localisation studies conducted here revealed that SsAP is a strictacid protease present in the digestive tract and eggs of the scabies mite, with greatestexpression evident in the adult female mites. Recombinant SsAP from human mites,SsAP(Vh), was shown to digest haemoglobin, serum albumin, fibrinogen andfibronectin but not collagen III and laminin.In a comparative analysis of enzyme activity, it was observed that SsAP(Vh) canefficiently digest both human haemoglobin and human serum albumin, while SsAPfrom dog mites, SsAP(Vc), efficiently digests only human serum albumin. Thissuggests different dietary sources for these varieties of scabies mites and that theSsAP may determine the food preferences and host range of S. scabiei, as is the casein many other parasites. Using a combinatorial library approach the primary specificity of SsAP(Vh) wasdetermined to be P1-Leu and P1’-Val. The extended specificity of SsAP(Vh) wasalso determined and may be exploited in the design of specific peptidomimeticinhibitors. An SsAP inhibitor which significantly impacted mite digestion and orreproduction would be a useful addition to currently used scabicidal drugs. Thiswould offer an alternative mode of therapy in the current conditions of emergingresistance. A new drug for scabies has the potential to have a significant positiveimpact on the health status of disadvantaged populations living in scabies endemiccommunities globally.
Selective Partition of Caffeine from Coffee Bean and Guaraná Seed Extracts using Alcohol-Salt Aqueous Two-Phase Systems
Creators: name: Santos, Samuel B.
name: Reis, Igor A. O.
name: Silva, Camila P. C.
name: Andressa F. Campos
name: Ventura, Sónia P. M.
name: Cleide M. F. Soares
name: Lima, Álvaro S.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: This work proposes the application of flexible alcoholic aqueous two-phase systems (ATPS) to manipulate the partition of caffeine. An optimization study was performed the caffeine partitioning towards top phase (60.0 wt% 2-propanol + 20.0 wt% K3PO4 at 303 K - Kcaf = 3.4 and RT =89.1%) and bottom phase (60.0 wt% methanol + 17.5 wt% K2HPO4/KH2PO4 at 278 K - Kcaf = 0.06 and RB = 81.1%). These processes were evaluated by applying them to real biomass as guaraná seeds (purification factor –FP = 6.59 fold) and coffee beans (PF = 3.24 fold) for the 2-propanol and K2HPO4/KH2PO4 system.
On-line coupling of solid-phase extraction of phenols on porous graphitic carbon and LC separation on C18 silica gel column via subcritical water desorption
Creators: name: Borisova, Dina Rashidovna
name: Statkus, Mikhail Alexandrovich
name: Tsysin, Grigory Il’yich
name: Zolotov, Yury Alexandrovich
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Inorganic Chemistry
subject: Science Policy

description: An approach to the on-line coupling of solid-phase extraction on porous graphitic carbon (PGC) column and high performance liquid chromatography (HPLC) separation on octadecyl silica column is proposed. The approach includes extraction of phenols from 10 ml of water sample on PGC column; desorption with subcritical water at 175°C, injection of the eluate to the HPLC column and separation at ambient temperature with acetonitrile–water eluent. Limits of detection for UV detection of phenols were 1–5 μg l−1, and analyte peaks were 20–50% narrower than for direct injection of 20 μl of sample.
title: A Brief History of Human Time : Exploring a database of “notable people” (LIEPP Working Paper, n°46)
Creators: name: Gergaud, Olivier
name: Laouenan, Morgane
name: Wasmer, Etienne
Publisher: name: Sciences Po - LIEPP
Year: 2016
Subjects: subject: FOS: Social sciences
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: This paper describes a database of 1,243,776 notable people and 7,184,575 locations (Geolinks) associated with them throughout human history. We first describe in details the various approches and procedures adopted to extract the relevant informationfrom their Wikipedia biographies and then analyze the database.
RNA binding specificity of Ebola virus transcription factor VP30
Creators: name: Schlereth, Julia
name: Grünweller, Arnold
name: Biedenkopf, Nadine
name: Becker, Stephan
name: Hartmann, Roland K.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: The transcription factor VP30 of the non-segmented RNA negative strand Ebola virus balances viral transcription and replication. Here, we comprehensively studied RNA binding by VP30. Using a novel VP30:RNA electrophoretic mobility shift assay, we tested truncated variants of 2 potential natural RNA substrates of VP30 - the genomic Ebola viral 3′-leader region and its complementary antigenomic counterpart (each ∼155 nt in length) - and a series of other non-viral RNAs. Based on oligonucleotide interference, the major VP30 binding region on the genomic 3′-leader substrate was assigned to the internal expanded single-stranded region (∼ nt 125–80). Best binding to VP30 was obtained with ssRNAs of optimally ∼ 40 nt and mixed base composition; underrepresentation of purines or pyrimidines was tolerated, but homopolymeric sequences impaired binding. A stem-loop structure, particularly at the 3′-end or positioned internally, supports stable binding to VP30. In contrast, dsRNA or RNAs exposing large internal loops flanked by entirely helical arms on both sides are not bound. Introduction of a 5´-Cap(0) structure impaired VP30 binding. Also, ssDNAs bind substantially weaker than isosequential ssRNAs and heparin competes with RNA for binding to VP30, indicating that ribose 2′-hydroxyls and electrostatic contacts of the phosphate groups contribute to the formation of VP30:RNA complexes. Our results indicate a rather relaxed RNA binding specificity of filoviral VP30, which largely differs from that of the functionally related transcription factor of the Paramyxoviridae which binds to ssRNAs as short as 13 nt with a preference for oligo(A) sequences.
As atitudes dos alunos para com a Matemática: Um estudo em duas turmas do 6.º ano do Ensino Básico
Creators: name: Ali Monteiro, Sara Andreia
name: Rodrigues, Margarida Amaro Teixeira
Publisher: name: CIED - Centro Interdisciplinar de Estudos Educacionais
Year: 2020

description: O presente artigo[1] irá incidir sobre um estudo realizado ao longo do ano letivo de 2017/2018, no âmbito da “Prática de Ensino Supervisionada II” do Mestrado em Ensino do 1.º Ciclo do Ensino Básico e de Matemática e Ciências Naturais no 2.º Ciclo do Ensino Básico. Este estudo teve como objetivo conhecer as atitudes dos alunos de uma turma do 6.º ano do ensino básico para com a Matemática antes e após o período de intervenção, de modo a compará-las e a compreender que aspetos da prática interventiva podem ter influenciado eventuais mudanças de atitude. Para tal, optou-se por uma metodologia quantitativa e, como método de recolha de dados, foram aplicados questionários, com itens fechados e abertos, antes e após o período de intervenção, assim como foram realizadas entrevistas aos alunos que mais diferenças mostraram entre estes dois períodos. Embora não se tenha verificado uma diferença significativa na atitude dos alunos para com a disciplina, em termos gerais o grupo evoluiu no que diz respeito a este domínio. Os resultados, para além de mostrarem que os alunos se sentem mais apoiados quando estão mais professoras presentes na sala de aula, também evidenciam que o tipo de atividades que foram desenvolvidas durante o período de intervenção – atividades exploratórias com recurso a materiais manipuláveis – também constituem uma motivação extra para que os discentes se envolvam no trabalho matemático em sala de aula. [1] O presente artigo constitui-se numa versão ampliada da comunicação realizada para o IV Encontro de Mestrados de Educação e Ensino que decorreu em novembro de 2018 na Escola Superior de Educação de Lisboa.
description: Da Investigação às Práticas: Estudos de Natureza Educacional, v. 10, n. 1 (2020)
Formação contínua de professores de Português do Ensino Básico em São Tomé e Príncipe: uma proposta de oficina de formação sobre ensino e avaliação da escrita
Creators: name: Gorgulho, Ana Rita
name: Santos, Leonor
name: Costa, Nilza
name: Sousa, Antónia Luísa
Publisher: name: CIED - Centro Interdisciplinar de Estudos Educacionais
Year: 2020

description: São Tomé e Príncipe (STP) apresenta um elevado número de professores sem habilitação profissional para a docência, situação que se deve, em parte, à tentativa de cumprimento da meta de universalização do ensino obrigatório, definida pela UNESCO[1] . Reconhecendo-se que a formação contínua (FC) oferece aos professores a oportunidade de se desenvolverem profissionalmente, nomeadamente em contextos em que educação e formação são consideradas alicerces estruturantes para o progresso do país[2], está em curso um estudo em torno da FC, centrado no ensino e avaliação da escrita em Língua Portuguesa (LP), numa perspetiva de cooperação para o desenvolvimento na formação de professores. Neste âmbito, seguindo uma abordagem qualitativa em que se privilegiou a análise documental (estudos sobre o contexto) e de conteúdo (respostas a um questionário), e com base na revisão de literatura sobre FC e ensino e avaliação da produção escrita, concebeu-se uma oficina de formação (OF) destinada a professores são-tomenses de LP do 2.º ciclo do ensino básico. A principal finalidade deste artigo é descrever, sustentadamente, a OF, concebida com base no pressuposto de que o desenvolvimento profissional decorre da articulação entre a formação e o contexto educativo. [1] Cf. Education for All 2000-2015: achievements and challenges (UNESCO, 2015). [2] Eixo da Educação de Excelência e Formação Profissionalizante, do Programa do XVII Governo Constitucional de STP (Governo de São Tomé e Príncipe, 2018).
description: Da Investigação às Práticas: Estudos de Natureza Educacional, v. 10, n. 1 (2020)
IIHS head restraint ratings and insurance injury claim rates
Creators: name: Trempel, Rebecca E.
name: Zuby, David S.
name: Edwards, Marcy A.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Objectives: The Insurance Institute for Highway Safety (IIHS) rates front seat/head restraint designs using a combination of static and dynamic measurements following RCAR-IIWPG procedures. The purpose of this study was to determine whether vehicles with better IIHS-rated seats/head restraints had lower injury risk in rear-end collisions and how the effect of better rated seats interacted with driver gender and age. Methods: The presence of an associated insurance injury claim was determined for rear-impact crashes using 2001–2014 model year cars and SUVs. Logistic regression was used to compare injury risk for vehicles with good, acceptable, and marginal IIHS-rated seats/head restraints with poor-rated seats/head restraints. Analyses were run by gender and driver age and also by the rate of more severe injury claims. Results: Injury rates were 11.2% lower for vehicles with seats/head restraints rated good compared to vehicles with seats/head restraints rated poor. The percentage reduction for good- versus poor-rated seats was greater for females (12.7%) than males (8.9%). Comparing good- with poor-rated seats, driver ages 15–24 had the largest reduction at 19.8%, followed by 10.7% for driver ages 45–64 and 10.4% for driver ages 25–44. Conclusions: Seats/head restraints with better IIHS ratings are associated with lower injury rates in rear-impact collisions than seats rated poor. The reductions in injury rates were strongest for females and for young-to–middle-age drivers. The strong reductions in injury rates for these groups are encouraging given their high initial injury rates.
O género gramatical no nome: dos documentos normativos aos manuais escolares de português do 1.º CEB
Creators: name: Lopes, Ana Sofia
name: Morgado, Celda
Publisher: name: CIED - Centro Interdisciplinar de Estudos Educacionais
Year: 2020

description: O género, como formalismo da língua e marca de concordância, existe somente em línguas que possuem concordância nominal, como o Português Europeu (PE). Esta categoria, no PE, corresponde a uma propriedade inerente aos nomes e são múltiplos os processos fonológicos, morfológicos e sintáticos subjacentes à variação em género nos nomes. Neste estudo exploratório pretendeu-se averiguar como é preconizado o tratamento categoria nominal supracitada nos documentos reguladores de Ensino do Português no 1.º Ciclo do Ensino Básico (CEB) e investigar como é apresentado cientificamente e proposto pedagogicamente em manuais escolares dos 1.º ao 4.º anos.
description: Da Investigação às Práticas: Estudos de Natureza Educacional, v. 10, n. 1 (2020)
In Vivo and protease-activated receptor-1-mediated platelet activation in patients presenting for cardiac catheterization
Creators: name: Gremmel, Thomas
name: Michelson, Alan D.
name: Frelinger, Andrew L.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: Computational Biology

description: Pathways of platelet activation that are not targeted by current antithrombotic therapy may be crucial for the development of ischemic events in patients undergoing coronary angiography. We therefore investigated whether in vivo and thrombin receptor activating peptide (TRAP)-stimulated platelet activation and monocyte-platelet aggregate (MPA) levels can serve as independent risk markers for adverse outcomes in aspirin-treated patients presenting for cardiac catheterization. In vivo and TRAP-stimulated platelet surface P-selectin, activated glycoprotein IIb/IIIa (GPIIb/IIIa) and MPA levels were determined in 682 consecutive patients undergoing cardiac catheterization and in 47 healthy controls. Two-year follow-up data were obtained from 562 patients. In vivo platelet surface P-selectin, activated GPIIb/IIIa and MPA levels were significantly higher in patients with angiographically-proven coronary artery disease than in healthy controls (all p≤0.02). Patients with an acute coronary syndrome (ACS; n=125) had significantly higher levels of in vivo MPA than patients without ACS (n=437; p=0.01). In the overall study population (n=562) the surface expression of P-selectin and activated GPIIb/IIIa, and the levels of MPA in vivo and in response to TRAP were similar in patients without and with subsequent ischemic events (all p>0.05). Similar results were obtained when only patients with angiographically-proven coronary artery disease (n=459), stent implantation (n=205) or ACS (n=125) were analyzed. Receiver-operating characteristic curve analyses did not reveal cut-off values for P-selectin, activated GPIIb/IIIa, and MPA levels for the prediction of ischemic events. In conclusion, in vivo and TRAP-stimulated platelet activation and MPA levels did not predict adverse ischemic outcomes in aspirin-treated patients presenting for cardiac catheterization.
Didática da Língua Materna e Metodologia de Trabalho de Projeto: Diálogos e Interseções
Creators: name: Ferreira, Patricia
name: Estrela, Antónia
name: Oliveira, Ana Luísa
name: Abrantes, Ana
Publisher: name: CIED - Centro Interdisciplinar de Estudos Educacionais
Year: 2020

description: Pretende-se apresentar uma análise do papel desempenhado pela língua na metodologia de trabalho de projeto e das aprendizagens linguísticas assim desencadeadas. A partir da análise de materiais didáticos, produções das crianças, registos fotográficos de situações de ensino e aprendizagem e relatos de ocorrências, são discutidos tópicos em torno de dois eixos: a forma como as competências nucleares da língua contribuem para a realização de trabalhos de projeto (i) e o impulso que estes imprimem às aprendizagens linguísticas nos domínios referidos (ii). A análise realizada evidenciou a relação dialógica que se estabelece entre a construção de conhecimentos específicos relacionados com a temática dos projetos e a área científica ou artística em que se inserem e o desenvolvimento de competências linguísticas, destacando-se: a) a relevância de um trabalho explícito focalizado na didática da língua na preparação da realização de trabalhos de projeto e nas várias fases que estes atravessam; b) a riqueza de que se reveste esta metodologia para a contextualização das aprendizagens linguísticas; c) os benefícios que tais contextos envolvem para a construção de saberes em uso, de natureza complexa, que enformam o conceito de literacia e que potenciam o exercício da cidadania. Palavras-chave: Metodologia de trabalho de projeto; Didática da língua materna; Integração curricular; Literacia.
description: Da Investigação às Práticas: Estudos de Natureza Educacional, v. 10, n. 1 (2020)