cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: L’enseignement de la musique et la sculpture de soi
Creators: name: Stoianova , Ivanka
Publisher: name: Roma Tre-Press
Year: 2010

description: L'importanza della musica come strategia educativa nella costruzione del sé è sottolineata con forza in questo saggio in cui si analizza il ruolo dell'istruzione musicale nel sistema formativo francese. L'insegnamento della musica sia nella scuola primaria che nei licei francesi è lasciato all'iniziativa dell'insegnante, alla sua formazione musicale, ai suoi interessi personali e, naturalmente, al livello motivazionale dei suoi allievi. Questo non è tuttavia sufficiente per raggiungere una conoscenza, anche sommaria e appena soddisfacente, della cultura musicale.

description: B@belonline vol. 8 Musica e Bildung. Saper suonare e imparare ad ascoltare
Tudor: a versatile family of histone methylation ‘readers’
Creators: name: Lu, Rui
name: Wang, Gang Greg
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The Tudor domain comprises a family of motifs that mediate protein-protein interactions required for various DNA-templated biological processes. Emerging evidence demonstrates a versatility of the Tudor family domains by identifying their specific interactions to a wide variety of histone methylation marks. Here, we discuss novel functions of a number of Tudor-containing proteins (including JMJD2A, 53BP1, SGF29, Spindlin1, UHRF1, PHF1, PHF19 and SHH1) in ‘reading’ unique methylation events on histones in order to facilitate DNA damage repair or regulate transcription. This review covers our recent understanding of the molecular bases for histone-Tudor interactions and their biological outcomes. As deregulation of Tudor-containing proteins is associated with certain human disorders, pharmacological targeting of Tudor interactions could provide new avenues for therapeutic intervention.
Simulation and performance of an artificial retina for 40 MHz track reconstruction
Creators: name: Abba, A.
name: Bedeschi, F.
name: Citterio, M.
name: Caponio, F.
name: Cusimano, A.
name: Geraci, A.
name: Marino, P.
name: Morello, M. J.
name: Neri, N.
name: Punzi, G.
name: Piucci, A.
name: Ristori, L.
name: Spinella, F.
name: Stracka, S.
name: Tonelli, D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present the results of a detailed simulation of the artificial retina pattern-recognition algorithm, designed to reconstruct events with hundreds of charged-particle tracks in pixel and silicon detectors at LHCb with LHC crossing frequency of $40\,\rm MHz$. Performances of the artificial retina algorithm are assessed using the official Monte Carlo samples of the LHCb experiment. We found performances for the retina pattern-recognition algorithm comparable with the full LHCb reconstruction algorithm.
description: Final draft of WIT proceedings modified according to JINST referee's comments
QUANTUM NEUROENHANCEMENT - NAVIGATING THE ETHICAL FRONTIERS OF HUMAN POTENTIAL
Creators: name: Brandl, Edenilson
Publisher: name: Zenodo
Year: 2023
Subjects: Quantum neuroscience
Subatomic particles
Quantenneurowissenschaft
Subatomare Teilchen

description: This article delves into the intersection of quantum physics and neuroscience, exploring the theoretical framework of inserting trained subatomic particles into brain cells for neuroenhancement. It examines the potential of this innovative approach in augmenting human cognition, accelerating learning, enhancing problem-solving abilities, and fostering creativity. While promising, the article emphasizes the critical importance of ethical considerations, individual consent, and societal impact. It advocates for responsible innovation through interdisciplinary collaboration, rigorous ethical deliberation, and open dialogue among scientists, ethicists, policymakers, and the public. The article highlights the need to strike a balance between individual freedoms and societal well-being, paving the way for a future where human potential is harnessed responsibly and ethically.
 
Dieser Artikel befasst sich mit der Schnittstelle zwischen Quantenphysik und Neurowissenschaften und untersucht den theoretischen Rahmen für die Einführung trainierter subatomarer Partikel in Gehirnzellen zur Neuroverstärkung. Es untersucht das Potenzial dieses innovativen Ansatzes zur Erweiterung der menschlichen Kognition, zur Beschleunigung des Lernens, zur Verbesserung der Problemlösungsfähigkeiten und zur Förderung der Kreativität. Der Artikel ist zwar vielversprechend, betont aber die entscheidende Bedeutung ethischer Überlegungen, der individuellen Zustimmung und der gesellschaftlichen Auswirkungen. Es setzt sich für verantwortungsvolle Innovation durch interdisziplinäre Zusammenarbeit, strenge ethische Überlegungen und einen offenen Dialog zwischen Wissenschaftlern, Ethikern, politischen Entscheidungsträgern und der Öffentlichkeit ein. Der Artikel unterstreicht die Notwendigkeit, ein Gleichgewicht zwischen individuellen Freiheiten und gesellschaftlichem Wohlergehen zu finden und den Weg für eine Zukunft zu ebnen, in der das menschliche Potenzial verantwortungsvoll und ethisch genutzt wird.
High-scale validity of a two-Higgs doublet scenario: a study including LHC data
Creators: name: Chakrabarty, Nabarun
name: Dey, Ujjal Kumar
name: Mukhopadhyaya, Biswarup
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider the conditions for the validity of a two-Higgs doublet model at high energy scales, together with all other low- and high-energy constraints. The constraints on the parameter space at low energy, including the measured value of the Higgs mass and the signal strengths in channels are juxtaposed with the conditions of vacuum stability, perturbativity and unitarity at various scales. We find that a scenario with an exact $\mathbb{Z}_2$ symmetry in the potential cannot be valid beyond about 10 TeV without the intervention of additional physics. On the other hand, when the $\mathbb{Z}_2$ symmetry is broken, the theory can be valid even up to the Planck scale without any new physics coming in. The interesting feature we point out is that such high-scale validity is irrespective of the uncertainty in the top quark mass as well as $α_{s}(M_Z)$, in contrast with the standard model with a single Higgs doublet. It is also shown that the presence of a CP-violating phase is allowed when the $\mathbb{Z}_2$ symmetry is relaxed. The allowed regions in the parameter space are presented for each case. The results are illustrated in the context of a Type-II scenario.
description: 38 pages, 12 figures. Major changes in the presentation of some of the plots, minor changes in the text, references added, typos corrected, matches with published version
Direct collapse black hole formation from synchronized pairs of atomic cooling halos
Creators: name: Visbal, Eli
name: Haiman, Zoltan
name: Bryan, Greg L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: High-redshift quasar observations imply that supermassive black holes (SMBHs) larger than $\sim 10^9 ~ M_\odot$ formed before $z=6$. That such large SMBHs formed so early in the Universe remains an open theoretical problem. One possibility is that gas in atomic cooling halos exposed to strong Lyman-Werner (LW) radiation forms $10^4-10^6 ~ M_\odot$ supermassive stars which quickly collapse into black holes. We propose a scenario for direct collapse black hole (DCBH) formation based on synchronized pairs of pristine atomic cooling halos. We consider halos at very small separation with one halo being a subhalo of the other. The first halo to surpass the atomic cooling threshold forms stars. Soon after these stars are formed, the other halo reaches the cooling threshold and due to its small distance from the newly formed galaxy, is exposed to the critical LW intensity required to form a DCBH. The main advantage of this scenario is that synchronization can potentially prevent photoevaporation and metal pollution in DCBH-forming halos. Since the halos reach the atomic cooling threshold at nearly the same time, the DCBH-forming halo is only exposed to ionizing radiation for a brief period. Tight synchronization could allow the DCBH to form before stars in the nearby galaxy reach the end of their lives and generate supernovae winds. We use N-body simulations to estimate the abundance of DCBHs formed in this way. The largest source of uncertainty in our estimate is the initial mass function (IMF) of metal free stars formed in atomic cooling halos. We find that even for tight synchronization, the density of DCBHs formed in this scenario could explain the SMBHs implied by $z=6$ quasar observations. Metal pollution and photoevaporation could potentially reduce the abundance of DCBHs below that required to explain the observations in other models that rely on a high LW flux.
description: 8 pages, 4 figures, replaced with version accepted by MNRAS
Nucleon tensor charge from Collins azimuthal asymmetry measurements
Creators: name: Kang, Zhong-Bo
name: Prokudin, Alexei
name: Sun, Peng
name: Yuan, Feng
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the nucleon tensor charge from current experiments by a combined analysis of the Collins asymmetries in two hadron production in $e^+e^-$ annihilations and semi-inclusive hadron production in deep inelastic scattering processes. The transverse momentum dependent evolution is taken into account, for the first time, in the global fit of the Collins fragmentation functions and the quark transversity distributions at the approximate next-to-leading logarithmic order. We obtain the nucleon tensor charge contribution from up and down quarks as $δu=+0.30^{+0.12}_{-0.08}$ and $δd=-0.20_{-0.11}^{+0.28}$ at 90\% confidence level for momentum fraction $0.0065 \le x_B \le 0.35$ and $Q^2=$ 10 GeV$^2$.
description: Version published in Physical Review - Rapid Communications, improved discussion, additional references and formulas added
Allosteric sodium in class A GPCR signaling
Creators: name: Katritch, Vsevolod
name: Cherezov, Vadim
name: Stevens, Raymond C.
name: Roth, Bryan L.
name: Fenalti, Gustavo
name: Abola, Enrique E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Despite their functional and structural diversity, G protein-coupled receptors (GPCRs) share a common mechanism of signal transduction via conformational changes in the seven-transmembrane (7TM) helical domain. New major insights into this mechanism come from the recent crystallographic discoveries of a partially hydrated sodium ion that is specifically bound in the middle of the 7TM bundle of multiple class A GPCRs. This review discusses the remarkable structural conservation and distinct features of the Na+ pocket in this most populous GPCR class, as well as the conformational collapse of the pocket on receptor activation. New insights help to explain allosteric effects of sodium on GPCR agonist binding and activation, and sodium’s role as a potential co-factor in class A GPCR function.
Rokhlin dimension for actions of residually finite groups
Creators: name: Szabo, Gabor
name: Wu, Jianchao
name: Zacharias, Joachim
Publisher: name: arXiv
Year: 2014
Subjects: subject: Operator Algebras (math.OA)
subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 46L55, 54H20 (Primary), 46L35, 20F69, 20F18 (Secondary)

description: We introduce the concept of Rokhlin dimension for actions of residually finite groups on C*-algebras, extending previous notions of Rokhlin dimension for actions of finite groups and the integers, as introduced by Hirshberg, Winter and the third author. If the group has a box space of finite asymptotic dimension, then actions with finite Rokhlin dimension preserve the property of having finite nuclear dimension, when passing to the crossed product C*-algebra. A detailed study of the asymptotic dimension of box spaces shows that finitely generated, virtually nilpotent groups have box spaces with finite asymptotic dimension, providing a reasonably large class of examples. We then establish a relation between Rokhlin dimension of residually finite groups acting on compact metric spaces and amenability dimension of the action in the sense of Guentner, Willett and Yu. We show that for free actions of infinite, finitely generated, nilpotent groups on finite dimensional spaces, both these dimensional values are finite. In particular, the associated transformation group C*-algebras have finite nuclear dimension. This extends an analogous result about $\mathbb{Z}^m$-actions by the first author. We also provide some results concerning the genericity of finite Rokhlin dimension, and permanence properties with respect to the absorption of a strongly self-absorbing C*-algebra.
description: 64 pages; some small corrections and added remarks
KRAS: feeding pancreatic cancer proliferation
Creators: name: Mancias, Joseph D.
name: Kimmelman, Alec C.
name: Der, Channing J.
name: Bryant, Kirsten L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Oncogenic KRAS mutation is the signature genetic event in the progression and growth of pancreatic ductal adenocarcinoma (PDAC), an almost universally fatal disease. Although it has been appreciated for some time that nearly 95% of PDAC harbor mutationally activated KRAS, to date no effective treatments that target this mutant protein have reached the clinic. A number of studies have shown that oncogenic KRAS plays a central role in controlling tumor metabolism by orchestrating multiple metabolic changes including stimulation of glucose uptake, differential channeling of glucose intermediates, reprogrammed glutamine metabolism, increased autophagy, and macropinocytosis. Here we review these recent findings and address how they may be applied to develop new PDAC treatments.
title: The LIBERATOR Archive, October 2017
title: Official Publication of the Liberal Arts Council
titleType: AlternativeTitle
Creators: name: University Of Texas At Austin
Publisher: name: University of Texas at Austin
Year: 2017
Subjects: Liberal Arts
Beto O'Rourke
Trump
sexual assault
student empowerment
mental health
Austin
non-profits

description: Contents: October 2, 2017 The Power of the Mind / by Jacob Hood -- October 5, 2017 Student Empowerment in the Age of Trump / by Varun Hukeri -- October 9, 2017 A City Divided / by Robyn Yeh -- October 13, 2017 Changing the World? (Yes, You Are.) / by McKenzie Hohenberger -- October 16, 2017 "Iron” / by Siqi Jiang -- October 20, 2017 Throwback to Tribune: “One on One with Beto O’Rourke” / by Christina Lopez -- October 26, 2017 Throwback to Tribune: Veep Imitates Life / by Brooke Quach -- October 29, 2017 Throwback to Tribune: The Right Response on Sexual Assault / by Varun Hukeri -- October 30, 2017 Liberal Arts Week: Love Letters for Liberal Arts / by Hira Vayani -- October 31, 2017 Liberal Arts Week: Non-Profits and the Liberal Arts / by Varun Hukeri
Nitrate Deposition following an Astrophysical Ionizing Radiation
Creators: name: Neuenswander, Ben
name: Melott, Adrian
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Geophysics (physics.geo-ph)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: It is known that a gamma ray burst (GRB) originating near the Earth could be devastating to life. The mechanism of ozone depletion and subsequent increased UVB exposure is the primary risk, but models also show increased nitrification culminating in nitric acid rainout. These effects are also expected after nearby supernovae and extreme solar proton events. In this work we considered specifically whether the increased nitric acid rainout from such events is a threat to modern terrestrial ecosystems. We also considered its potential benefit to early terrestrial Paleozoic ecosystems. We used established critical loads for nitrogen deposition in ecoregions of Europe and the US and compared them with previously predicted values of nitric acid rainout from a typical GRB within our galaxy. The predicted rainout was found to be too low to harm modern ecosystems, however, it is large compared with probable nitrate flux onto land prior to the invasion of plants. We suggest that this flux may have contributed nutrients to this invasion if, as hypothesized, the end-Ordovician extinction event were initiated by a GRB or other ionizing radiation event.
description: Advances in Space Research, in press
Additional file 1 of Rational design of an essential diagnostics network to support Universal Health Coverage: a modeling analysis
Creators: name: Schroeder, Lee F.
name: Dei-Adomakoh, Yvonne
name: DeStigter, Kristen
name: Idigbe, Emmanuel O.
name: Flanigan, John
name: Ekpale, Priscilla Mawuli Awo
name: Adjei, Ernest
name: Roa, Lina
name: Wilson, Michael L.
name: Horton, Susan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Supplementary Figure S1. Cumulative Number of Diagnostics with Additional Diseases. Supplementary Table S1. Definitions of disease levels (uncomplicated vs complicated). Supplementary Table S2. Mapping of medicines to disease levels. Supplementary Table S3. Mapping of diagnostics to disease levels. Supplementary Table S4. Mapping of diagnostics to diagnostic formats. Supplementary Table S5. Infrastructural limitations of diagnostic formats. Supplementary Table S6. Model output of diagnostics by health facility tier. Supplementary Table S7. Minimum equipment investment and workforce skill needs, by health system tier.
Intermittency and dynamical Lee-Yang zeros of open quantum systems
Creators: name: Hickey, James M.
name: Flindt, Christian
name: Garrahan, Juan P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We use high-order cumulants to investigate the Lee-Yang zeros of generating functions of dynamical observables in open quantum systems. At long times the generating functions take on a large deviation form with singularities of the associated cumulant generating functions - or dynamical free energies - signifying phase transitions in the ensemble of dynamical trajectories. We consider a driven three-level system as well as the dissipative Ising model. Both systems exhibit dynamical intermittency in the statistics of quantum jumps. From the short-time behavior of the dynamical Lee-Yang zeros we identify critical values of the counting field which we attribute to the observed intermittency and dynamical phase co-existence. Furthermore, for the dissipative Ising model we construct a trajectory phase diagram and estimate the value of the transverse field where the stationary state changes from being ferromagnetic (inactive) to being paramagnetic (active).
description: 11 pages, 4 figures, final version as published in Phys. Rev. E
The growth–defense pivot: crisis management in plants mediated by LRR-RK surface receptors
Creators: name: Chory, Joanne
name: Yang, Li
name: Belkhadir, Youssef
name: Dangl, Jeffery L.
name: Hetzel, Jonathan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Plants must adapt to their environment and require mechanisms for sensing their surroundings and responding appropriately. An expanded family of greater than 200 leucine-rich repeat receptor kinases (LRR-RKs) transduces fluctuating and often contradictory signals from the environment into changes in nuclear gene expression. Two LRR-RKs, BRASSINOSTEROID INSENSITIVE 1 (BRI1), a steroid receptor, and FLAGELLIN-SENSITIVE 2 (FLS2), an innate immune receptor that recognizes bacterial flagellin, act cooperatively to partition necessary growth-defense tradeoffs. BRI1 and FLS2 share common signaling components and slightly different activation mechanisms. BRI1 and FLS2 are paradigms for understanding signaling mechanisms of LRR-containing receptors in plants.
Buenas Prácticas en los Procesos Editoriales de Revistas Científicas para LILACS (2021) - Sesión V - "Plágio y Retractación en la Publicación Científica"
Creators: name: BIREME/OPS/OMS
name: Calò, Lilian
Publisher: name: Zenodo
Year: 2021
Subjects: buenas prácticas
ciencia aberta
LILACS
editores LILACS
revistas LILACS
buenas prácticas editoriales

description: • Sesión 05 | 21 de julio de 2021 • Tema: "Plagio y retractación en la publicación científica" • Ponente: Drª Lilian Calò Más informaciones → https://bit.ly/buenaspracticaslilacs2021
Physical samples & RDA
Creators: name: Plomp, Esther
Publisher: name: Zenodo
Year: 2023
Subjects: RDA
RDM
Physical samples
Research Data Management
FAIR

description: Presentation by Esther Plomp for the Workshop on FAIR for Physical Objects (Utrecht, 2023-03-01). This presentation provides an overview of the activities from the Research Data Alliance Interest Group on Physical Samples. Link to the Interest group: IG Physical Samples and Collections in the Research Data Ecosystem
Additional file 1 of Comparison of PSMA-TO-1 and PSMA-617 labeled with gallium-68, lutetium-177 and actinium-225
Creators: name: Meyer, Catherine
name: Prasad, Vikas
name: Stuparu, Andreea
name: Kletting, Peter
name: Glatting, Gerhard
name: Miksch, Jonathan
name: Solbach, Christoph
name: Lueckerath, Katharina
name: Nyiranshuti, Lea
name: Zhu, Shaojun
name: Czernin, Johannes
name: Beer, Ambros J.
name: Slavik, Roger
name: Calais, Jeremie
name: Dahlbom, Magnus
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Cancer
subject: Hematology
subject: Computational Biology

description: Additional file 1: Supplementary preclinical and clinical information.
Global dynamics and inflationary center manifold and slow-roll approximants
Creators: name: Alho, Artur
name: Uggla, Claes
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We consider the familiar problem of a minimally coupled scalar field with quadratic potential in flat Friedmann-Lemaître-Robertson-Walker cosmology to illustrate a number of techniques and tools, which can be applied to a wide range of scalar field potentials and problems in e.g. modified gravity. We present a global and regular dynamical systems description that yields a global understanding of the solution space, including asymptotic features. We introduce dynamical systems techniques such as center manifold expansions and use Padé approximants to obtain improved approximations for the `attractor solution' at early times. We also show that future asymptotic behavior is associated with a limit cycle, which shows that manifest self-similarity is asymptotically broken toward the future, and give approximate expressions for this behavior. We then combine these results to obtain global approximations for the attractor solution, which, e.g., might be used in the context of global measures. In addition we elucidate the connection between slow-roll based approximations and the attractor solution, and compare these approximations with the center manifold based approximants.
description: 32 pages, 24 figures. Appendices incorporated into main text. Matches final published version
Realidade Aumentada e Virtual na Produção Lean
Creators: name: Brandl, Edenilson
Publisher: name: Zenodo
Year: 2023
Subjects: Realidade Aumentada
Realidade Virtual
Produção Lean
Eficiência Operacional
Feedback em Tempo Real
Melhoria da Qualidade
Detecção de Defeitos
Ergonomia
Visualização de Dados
Integração Tecnológica

description: A integração da Realidade Aumentada e Virtual na Produção Lean não é apenas uma evolução tecnológica, mas também uma revolução nos processos industriais. Ao capacitar as equipes com feedback em tempo real, reduzir erros e aumentar a precisão, essas tecnologias não apenas otimizam a produção, mas também transformam a forma como os negócios operam. Através dos exemplos práticos e das aplicações apresentadas, fica claro que essas inovações não são apenas conceitos futuristas, mas sim soluções tangíveis e poderosas para alcançar a excelência na produção, impulsionando a eficiência, a qualidade e a competitividade no mundo industrial moderno. O futuro da produção lean, enriquecido pela realidade aumentada e virtual, é emocionante e promissor, abrindo portas para um novo horizonte de possibilidades e oportunidades.
The spatial distributions of chiral magnetic field in the RHIC and LHC energy regions
Creators: name: Zhong, Yang
name: Yang, Chun-Bin
name: Cai, Xu
name: Feng, Sheng-Qin
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Relativistic heavy-ion collisions can produce extremely strong magnetic field in the collision regions. The spatial variation features of the magnetic fields are analyzed in detail for non-central Pb - Pb collisions at LHC $\sqrt{s_{NN}}$= 900, 2760 and 7000 GeV and Au-Au collisions at RHIC $\sqrt{s_{NN}}$ = 62.4, 130 and 200 GeV. The dependencies of magnetic field on proper time, collision energies and impact parameters are investigated in this paper. It is shown that a enormous with highly inhomogeneous spatial distribution magnetic field can indeed be created in off-central relativistic heavy-ion collisions in RHIC and LHC energy regions. The enormous magnetic field is quite large, especially just after the collision, and then decreases rapidly with time. We are surprised to find that the magnetic effect decreases with increasing energy from RHIC to LHC energy region. It is found that the magnitude of magnetic field in the LHC energy region is far less than that of magnetic field in the RHIC energy region.
description: 10 pages, 15 figures
Additional file 1 of Randomized controlled trials in de-implementation research: a systematic scoping review
Creators: name: Raudasoja, Aleksi J.
name: Falkenbach, Petra
name: Vernooij, Robin W. M.
name: Mustonen, Jussi M. J.
name: Agarwal, Arnav
name: Aoki, Yoshitaka
name: Blanker, Marco H.
name: Cartwright, Rufus
name: Garcia-Perdomo, Herney A.
name: Kilpeläinen, Tuomas P.
name: Lainiala, Olli
name: Lamberg, Tiina
name: Nevalainen, Olli P. O.
name: Raittio, Eero
name: Richard, Patrick O.
name: Violette, Philippe D.
name: Komulainen, Jorma
name: Sipilä, Raija
name: Tikkinen, Kari A. O.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: eFigure1. Flow diagram. eFigure 2. Published studies per medical content area. eFigure 3. Risk of bias per question. eFigure 4. Risk of bias inside intervention categories. eFigure 5. Intervention components in single-component interventions. eMethods 1. Search strategies. eMethods 2. Risk of Bias Tool for RCTs of complex interventions. eMethods 3. Refined version of intervention taxonomy for de-implementation interventions. eMethods 4. Rationale for refined intervention taxonomy. eMethods 5. Rationale for outcome hierarchy of effectiveness outcomes in de-implementation. eMethods 6. Identified scoping and systematic reviews of de-implementation. eTable 1. Quality outcomes until 2010 and after. eTable 2. Theoretical background used in designing the interventions. eTable 3. Citations for included studies.
title: Zwischen Deutschland und Europa
Creators: name: Kuhfeldt, Liza
Year: 2022

description: Die Arbeit untersucht die Frage, inwiefern sich transnationale und nationale kollektive Identitätsangebote in Beiträgen des öffentlich-rechtlichen Fernsehens einschreiben. Die zugrundeliegende These geht davon aus, dass sich eine europäische Identität in televisuellen Codes anders niederschlägt als eine deutsche. Um dies zu untersuchen, wurden journalistisch-dokumentarische Beiträge des europäischen öffentlich-rechtlichen Senders arte sowie Inhalte des deutschen öffentlich-rechtlichen Fernsehens untersucht. Die Eingrenzung der Quellenauswahl auf das dokumentarische Genre ist darauf zurückzuführen, dass davon ausgegangen werden kann, dass aufgrund des ihnen innewohnenden Anspruchs an eine maximal authentische Abbildung der Wirklichkeit, besonders gut für das Forschungsvorhaben eignen. Im ersten Schritt wurde zum einen eine differenzierte Betrachtung des Forschungsfeldes zu Identitäten und der Rolle, die Medien beziehungsweise das Fernsehen im Konstruktionsprozess dieser spielen, erörtert. Hierauf aufbauend konnten spezifische Analyseraster für eine europäische und eine deutsche Identität auf Basis einschlägiger Literatur und aussagekräftiger Studien erarbeitet werden. Im zweiten Schritt wird den Sendeanstalten eine jeweilige Intention der Konstruktion der entsprechenden Identitätsangebote in ihrer Gründungsgeschichte sowie ihren heute bestehenden Strukturen nachgewiesen. Im dritten Schritt werden die Identitätsanalyseraster in detaillierten Fernsehanalysen auf zwei Quellenpaare angewendet. Die darauffolgende Gegenüberstellung zeigt für die arte-Beiträge ein eingeschriebenes, europäisches und für die Beiträge der deutschen Öffentlich-Rechtlichen ein eingeschriebenes, deutsches Identitätsangebot, welches aus den televisuellen Codes herausgelesen werden kann. Auf diese Weise werden die unterschiedlichen Ausprägungen der kollektiven Identitäten Europas und Deutschlands im Material sichtbar: von grundlegend unterschiedlichen Identitätsaspekten, wie der Frage des kontrastierenden Äußeren, bis zu feinen Nuancen, wie den unterschiedlichen Niederschlägen, die die nationalsozialistische Vergangenheit in das jeweilige Identitätskonstrukt fand.
Measuring enzyme activity in single cells
Creators: name: Allbritton, Nancy L.
name: Kovarik, Michelle L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Seemingly identical cells can differ in their biochemical state, function and fate, and this variability plays an increasingly recognized role in organism-level outcomes. Cellular heterogeneity arises in part from variation in enzyme activity, which results from interplay between biological noise and multiple cellular processes. As a result, single-cell assays of enzyme activity, particularly those that measure product formation directly, are crucial. Recent innovations have yielded a range of techniques to obtain these data, including image-, flow- and separation-based assays. Research to date has focused on easy-to-measure glycosylases and clinically-relevant kinases. Expansion of these techniques to a wider range and larger number of enzymes will answer contemporary questions in proteomics and glycomics, specifically with respect to biological noise and cellular heterogeneity.
Cardiac Muscle Ring Finger-1—Friend or Foe?
Creators: name: Zungu, Makhosazane
name: Willis, Monte S.
name: Patterson, Cam
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The ubiquitin proteasome system plays a role in regulating protein activity and is integral to the turnover of damaged and worn proteins. In this review, we discuss the recently described relationship between the ubiquitin proteasome system and the cardiac creatine kinase/phospho-creatine shuttle, an essential component of ATP generation and energy shuttling within the heart. The ubiquitin ligase muscle ring finger-1 (MuRF1) binds creatine kinase, leading to its ubiquitination and possible degradation. MuRF1 may also be integral in the regulation of creatine kinase activity in vivo. Since there is a close relationship between the cardiac creatine kinase/phospho-creatine shuttle activity and heart failure, these findings suggest that MuRF1’s role in protein quality control of creatine kinase may be vital to the regulation and maintenance of cardiac energetics to protect against heart failure.
Hyperlipidemia, tissue factor, coagulation, and simvastatin
Creators: name: Byrnes, James Robert
name: Owens, Albert Phillip
name: Mackman, Nigel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Hyperlipidemia affects millions of people worldwide and is a major risk factor for cardiovascular disease. People with hyperlipidemia have elevated levels of serum cholesterol and an increased risk of thrombosis. Studies have suggested that oxidized lipoproteins, such as oxidized low-density lipoprotein (oxLDL), contribute to the development of a pro-thrombotic state. In this review, we discuss our recent studies demonstrating a role for hematopoietic cell-derived tissue factor (TF) expression in the activation of coagulation and increased thrombosis associated with hyperlipidemia. In addition, we investigated the effect of simvastatin on TF expression and coagulation. We found that simvastatin reduced leukocyte TF expression, TF+ microparticles and coagulation. These results and earlier studies suggest that the anti-coagulant activity of statins is due, in part, to their ability to reduce monocyte TF expression in patients with cardiovascular disease.
The vertebrate cell kinetochore and its roles during mitosis
Creators: name: Rieder, Conly L
name: Salmon, E.D
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1998

description: A replicated chromosome possesses two discrete, complex, dynamic, macromolecular assemblies, known as kinetochores, that are positioned on opposite sides of the primary constriction of the chromosome. Here, the authors review how kinetochores control chromosome segregation during mitosis in vertebrates. They attach the chromosome to the opposing spindle poles by trapping the dynamic plus-ends of microtubules growing from the poles. They then produce much of the force for chromosome poleward motion, regulate when this force is applied, and act as a site for microtubule assembly and disassembly. Finally, they control the metaphase–anaphase transition by inhibiting chromatid separation until the chromatids are properly attached.
Exceptional thermodynamics: The equation of state of G(2) gauge theory
Creators: name: Bruno, Mattia
name: Caselle, Michele
name: Panero, Marco
name: Pellegrini, Roberto
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We present a lattice study of the equation of state in Yang-Mills theory based on the exceptional G(2) gauge group. As is well-known, at zero temperature this theory shares many qualitative features with real-world QCD, including the absence of colored states in the spectrum and dynamical string breaking at large distances. In agreement with previous works, we show that at finite temperature this theory features a first-order deconfining phase transition, whose nature can be studied by a semi-classical computation. We also show that the equilibrium thermodynamic observables in the deconfined phase bear striking quantitative similarities with those found in SU(N) gauge theories: in particular, these quantities exhibit nearly perfect proportionality to the number of gluon degrees of freedom, and the trace anomaly reveals a characteristic quadratic dependence on the temperature, also observed in SU(N) Yang-Mills theories (both in four and in three spacetime dimensions). We compare our lattice data with analytical predictions from effective models, and discuss their implications for the deconfinement mechanism and high-temperature properties of strongly interacting, non-supersymmetric gauge theories. Our results give strong evidence for the conjecture that the thermal deconfining transition is governed by a universal mechanism, common to all simple gauge groups.
description: 1+36 pages, 8 figures; v2, 1+41 pages, 9 figures: scale setting improved, discussion in section 1 slightly expanded, comments on the Monte Carlo algorithm added, new references included, affiliation details for one of the authors updated, minor misprints corrected: version published in the journal
Additional file 2 of Randomized controlled trials in de-implementation research: a systematic scoping review
Creators: name: Raudasoja, Aleksi J.
name: Falkenbach, Petra
name: Vernooij, Robin W. M.
name: Mustonen, Jussi M. J.
name: Agarwal, Arnav
name: Aoki, Yoshitaka
name: Blanker, Marco H.
name: Cartwright, Rufus
name: Garcia-Perdomo, Herney A.
name: Kilpeläinen, Tuomas P.
name: Lainiala, Olli
name: Lamberg, Tiina
name: Nevalainen, Olli P. O.
name: Raittio, Eero
name: Richard, Patrick O.
name: Violette, Philippe D.
name: Komulainen, Jorma
name: Sipilä, Raija
name: Tikkinen, Kari A. O.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist.
Chromophore-assisted laser inactivation in cell biology
Creators: name: Vitriol, Eric
name: Jacobson, Ken
name: Rajfur, Zenon
name: Hahn, Klaus
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Chromophore-assisted laser inactivation (CALI) is a technique whereby engineered proteins and dye molecules that produce substantial amounts of reactive oxygen species upon absorption of light are used to perturb biological systems in a spatially and temporally defined manner. CALI is an important complement to conventional genetic and pharmacological manipulations. In this review, we examine the applications of CALI to cell biology and discuss the underlying photochemical mechanisms that mediate this powerful technique.
Bayesian estimator of multiple Poisson means assuming two different priors
Creators: name: Ogura, Toru
name: Yanagimoto, Takemi
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: Computational Biology

description: This paper describes an empirical Bayesian estimator of multiple Poisson means based on a novel concept. The idea is to assume two different priors; Jeffreys’ prior for determining the hyperparameter and the uniform prior for the canonical parameter for estimating multiple Poisson means. The validity of this idea is discussed in detail. Furthermore, the empirical Bayesian estimator is constructed using the posterior mean of the canonical parameters instead of that of the mean parameters. The proposed estimator is evaluated using three familiar losses, and the results are found to be very promising. Finally, an actual dataset is analyzed to demonstrate the practical use of the proposed estimator.
Critical points of the linear entropy for pure L-qubit states
Creators: name: Maciazek, Tomasz
name: Sawicki, Adam
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We present a substancially improved version of the method proposed in Sawicki et al (2012, 2014) for finding critical points of the linear entropy for L-qubit system. The new approach is based on the corespondance between momentum maps for abelian and non-abelian groups, as described in Kirwan (1984). The proposed method can be implemented numerically much easier than the previous one.
description: 16 pages, 3 figures
Dynamical and Quenched Random Matrices and Homolumo Gap
Creators: name: Andric, Ivan
name: Jonke, Larisa
name: Jurman, Danijel
name: Nielsen, Holger Bech
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider a rather general type of matrix model, where the matrix M represents a Hamiltonian of the interaction of a bosonic system with a single fermion. The fluctuations of the matrix are partly given by some fundamental randomness and partly dynamically, even quantum mechanically. We then study the homolumo-gap effect, which means that we study how the level density for the single-fermion Hamiltonian matrix M gets attenuated near the Fermi surface. In the case of the quenched randomness (the fundamental one) dominating the quantum mechanical one we show that in the first approximation the homolumo gap is characterized by the absence of single-fermion levels between two steep gap boundaries. The filled and empty level densities are in this first approximation just pushed, each to its side. In the next approximation these steep drops in the spectral density are smeared out to have an error-function shape. The studied model could be considered as a first step towards the more general case of considering a whole field of matrices - defined say on some phase space - rather than a single matrix.
description: 15 pages, 2 figures; v2. substantial improvements, published in IJMPA
title: Quels sont les effets de l'expérimentation à l'aide d'une balance sur les représentations des élèves en termes de grandeur masse ?
title: Quels sont les effets de l'expérimentation à l'aide d'une balance sur les représentations des élèves en termes de grandeur masse ?
titleType: AlternativeTitle
Creators: name: Guisolan, Aline
name: Guisolan, Margaux
Publisher: name: Unknown
Year: 0
Subjects: subject: Mathématiques
subject: Expérimentation
subject: Balances
subject: Grandeur
subject: Mesure
subject: Masse
subject: Poids
subject: Enseignement

description: Ce travail traite de l’expérimentation de la grandeur masse dans le cadre des mathématiques à l’école primaire. Il a pour but d'examiner si l’expérimentation, à l’aide d’une balance à plateaux, favoriserait les représentations des élèves en termes de grandeur masse. Pour effectuer cette recherche, nous avons créé des balances à plateaux, puis élaboré 2 séquences d’enseignement étudiant la grandeur masse et sa mesure dans 2 classes distinctes, la classe A et la classe B. La classe A utilisait 10 balances à plateaux alors que la classe B se contentait uniquement de fiches et d’une balance exclusivement manipulée par l’enseignante. L’objectif étant de comparer les différents apprentissages acquis par les élèves dans chacune des classes à la fin de la séquence d'enseignement. Cette comparaison a pu être possible car les 40 élèves ont rempli un questionnaire en début de séquence et un test en fin de séquence. De plus, une étude comparative des questionnaires issus des 2 classes a démontré qu’il n’y avait pas de différences significatives en matière de connaissances initiales chez les élèves. A l’analyse des tests finaux, les résultats sont significatifs, la classe A avec expérimentation obtient de meilleurs résultats que la classe B sans matériel. L’expérimentation a donc des retombées positives sur les apprentissages des élèves car elle permet aux élèves d’observer les conséquences directes de leurs gestes et de réfléchir si ceux-ci permettent de résoudre l’exercice. L’expérimentation incite les élèves à organiser leurs idées. De plus, l’expérimentation permet aux élèves d’atteindre un haut niveau d’abstraction car ceux-ci peuvent s’appuyer sur l’expérience vécue pour construire des images mentales. Pour ces apprenants, les savoirs sont plus facilement mobilisables dans un contexte différent. Pour conclure, l’expérimentation permet aux apprenants d’aborder avec plus de facilité une discipline abstraite telle que les mathématiques car elle met les élèves en contexte réel, donnant ainsi du sens aux activités et aux mathématiques. L’expérimentation favorise grandement l’acquisition de nouveaux savoirs.
Nonlinear network dynamics under perturbations of the underlying graph
Creators: name: Radulescu, Anca
name: Verduzco-Flores, Sergio
Publisher: name: arXiv
Year: 2014
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences

description: Many natural systems are organized as networks, in which the nodes (be they cells, individuals or populations) interact in a time-dependent fashion. The dynamic behavior of these networks depends on how these nodes are connected, which can be understood in terms of an adjacency matrix, and connection strengths. The object of our study is to relate connectivity to temporal behavior in networks of coupled nonlinear oscillators. We investigate the relationship between classes of system architectures and classes of their possible dynamics, when the nodes are coupled according to a connectivity scheme that obeys certain constrains, but also incorporates random aspects. We illustrate how the phase space dynamics and bifurcations of the system change when perturbing the underlying adjacency graph. We differentiate between the effects on dynamics of the following operations that directly modulate network connectivity: (1) increasing/decreasing edge weights, (2) increasing/decreasing edge density, (3) altering edge configuration by adding, deleting or moving edges. We discuss the significance of our results in the context of real life networks. Some interpretations lead us to draw conclusions that may apply to brain networks, synaptic restructuring and neural dynamics.
description: 22 pages, 12 figures