cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Einfluss des Demenzgrades auf die motorischen Fähigkeiten von Senioren
Creators: name: Schumacher, Anneke
name: Prinz, Alexander
name: Witte, Kerstin
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: Demenz
subject: Kraftfähigkeiten
subject: Gleichgewicht
subject: Mobilität
subject: ADL
subject: 305.26

description: Hintergrund: Der progrediente Verlauf einer Demenzerkrankung äußert sich sowohl in den zunehmenden Beeinträchtigungen der kognitiven Funktionen als auch in den motorischen Fähigkeiten der Betroffenen und wirkt damit auf die Mobilität und Selbstständigkeit im Alltag aus. Die vorliegende Studie untersucht, ob und inwiefern der Schweregrad der Demenz ausgewählte motorische Leistungsfähigkeiten beeinflusst. Methodik: In die Studiewurden 32 SeniorenInnenmit einer leichtenDemenz (Gruppe A; Altersdurchschnitt: 84,3± 6,1 Jahre) und 27 SeniorInnen mit einer mittelschweren Demenz (Gruppe B; Altersdurchschnitt: 85,6± 5,5 Jahre) eingeschlossen, deren Einstufung anhand des Mini-Mental-Status-Tests (MMST) erfolgte. Zum Einsatz kamen folgende motorische Testverfahren: Handdynamometer (Gesamtkraftfähigkeit), Fall- Stab-Test (motorische Reaktionsfähigkeit), Frailty and Injuries: Cooperative Studies of Intervention Techniques (FICSIT-4; Gleichgewichtsfähigkeit), Timed-up-and-go-Test (TUG) und der modifizierte Chair-Rising-Test (CRT; beide analysieren die Mobilität und Transferleistung im Alltag). Ergebnisse: Gruppe A weist im Gegensatz zur Gruppe B eine signifikant bessere motorische Leistungsfähigkeit in allen motorischen Tests, außer dem Fall-Stab-Test, auf. Die größten Unterschiede liegen bei CRT (p= 0,000) und TUG (p= 0,011). Schlussfolgerung: Bezüglich der Handkraft, der Gleichgewichtsfähigkeit und der Mobilität weisen Menschen mit einem höheren Demenzgrad eine geringere Leistungsfähigkeit auf. In nachfolgenden Studien zur Auswirkung der Demenzerkrankung auf unterschiedliche Fähigkeiten und Fertigkeiten sollte deshalb stets eine Einteilung der Demenzgrade erfolgen. Zudem ist zu empfehlen, dass sich Interventionsprogram
The Golden Channel at a Neutrino Factory revisited: improved sensitivities from a Magnetised Iron Neutrino Detector
Creators: name: Bayes, R.
name: Laing, A.
name: Soler, F. J. P.
name: Villanueva, A. Cervera
name: Cadenas, J. J. Gómez
name: Hernández, P.
name: Martín-Albo, J.
name: Burguet-Castell, J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: This paper describes the performance and sensitivity to neutrino mixing parameters of a Magnetised Iron Neutrino Detector (MIND) at a Neutrino Factory with a neutrino beam created from the decay of 10 GeV muons. Specifically, it is concerned with the ability of such a detector to detect muons of the opposite sign to those stored (wrong-sign muons) while suppressing contamination of the signal from the interactions of other neutrino species in the beam. A new more realistic simulation and analysis, which improves the efficiency of this detector at low energies, has been developed using the GENIE neutrino event generator and the GEANT4 simulation toolkit. Low energy neutrino events down to 1 GeV were selected, while reducing backgrounds to the $10^{-4}$ level. Signal efficiency plateaus of ~60% for $ν_μ$ and ~70% for $\barν_μ$ events were achieved starting at ~5 GeV. Contamination from the $ν_μ\rightarrow ν_τ$ oscillation channel was studied for the first time and was found to be at the level between 1% and 4%. Full response matrices are supplied for all the signal and background channels from 1 GeV to 10 GeV. The sensitivity of an experiment involving a MIND detector of 100 ktonnes at 2000 km from the Neutrino Factory is calculated for the case of $\sin^2 2θ_{13}\sim 10^{-1}$. For this value of $θ_{13}$, the accuracy in the measurement of the CP violating phase is estimated to be $Δδ_{CP}\sim 3^\circ - 5^\circ$, depending on the value of $δ_{CP}$, the CP coverage at $5σ$ is 85% and the mass hierarchy would be determined with better than $5σ$ level for all values of $δ_{CP}$.
Antibiotic desensitization as a potential tool in antimicrobial stewardship programs: retrospective data analysis and systematic literature review
Creators: name: Rodríguez-Alarcón, Alicia
name: Barceló-Vidal, Jaime
name: Echeverría-Esnal, Daniel
name: Sorli, Luisa
name: Güerri-Fernández, Roberto
name: Fernández, Sofía Martina Ramis
name: Benitez-Cano, Adela
name: Sendra, Elena
name: Montesinos, Inmaculada López
name: Membrilla-Fernández, Estela
name: Ferrández, Olivia
name: Adalia, Ramón
name: Horcajada, Juan Pablo
name: Escolano, Fernando
name: Gómez-Zorrilla, Silvia
name: Grau, Santiago
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Antibiotic allergy labels (AAL) are related to worse therapeutic results. Strategies to improve the management of these patients, such as the implementation of antibiotic desensitization, are essential for Antimicrobial Stewardship Programs (ASP). The aim of our study is to evaluate the efficacy and safety of antibiotic desensitization procedures for the management of patients with AAL. A retrospective study from 2015 to 2022 was performed to describe all antibiotic desensitization conducted in our institution, within the framework of ASP. A systematic literature review using electronic databases, such as PubMed, was also done to identify studies describing antibiotic desensitization between 2000 and 2022. Sixteen antibiotic desensitization protocols were carried out in our institution. In fourteen cases, the desensitization was successfully completed, and the antibiotic could be used to treat the infection. In the systematic review, twenty-two studies were included, with a total of 202 desensitization episodes . In 97% of them, the desensitization was completed successfully. No desensitization-related mortality was observed neither in our cohort nor in literature review. Antibiotic desensitization strategies should be considered a safe and effective tool that can be included in ASP for patients with a high risk of or confirmed allergy to penicillin.
Shakedown of a CT specimen with St52 steel—experimental, analytical and numerical investigations
Creators: name: Huang, Y.J.
name: Stein, E.
Publisher: name: London : SAGE Publications Ltd.
Year: 1995
Subjects: subject: cyclical loading
subject: kinematic hardening
subject: plastic deformation
subject: shakedown behaviour
subject: Elastoplasticity
subject: Hardening
subject: Kinematics
subject: Load limits
subject: Loads (forces)
subject: Numerical analysis
subject: Steel
subject: Vibrations (mechanical)
subject: Cyclical loading
subject: Strain control
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: The paper deals with the shakedown behaviour of a CT (compact tension) specimen consisting of St52 steel under cyclical loading. Experiments have been carried out for determining the shakedown limit load. For comparison, the analytical and numerical methods are used to study the same problem. Satisfactory agreement has been achieved between the results from these different methods. © 1995, Institution of Mechanical Engineers. All rights reserved.
Towards the Recapitulation of Ancient History in the Laboratory: Combining Synthetic Biology with Experimental Evolution
Creators: name: Kacar, Betul
name: Gaucher, Eric
Publisher: name: arXiv
Year: 2012
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Molecular Networks (q-bio.MN)
subject: FOS: Biological sciences

description: One way to understand the role history plays on evolutionary trajectories is by giving ancient life a second opportunity to evolve. Our ability to empirically perform such an experiment, however, is limited by current experimental designs. Combining ancestral sequence reconstruction with synthetic biology allows us to resurrect the past within a modern context and has expanded our understanding of protein functionality within a historical context. Experimental evolution, on the other hand, provides us with the ability to study evolution in action, under controlled conditions in the laboratory. Here we describe a novel experimental setup that integrates two disparate fields - ancestral sequence reconstruction and experimental evolution. This allows us to rewind and replay the evolutionary history of ancient biomolecules in the laboratory. We anticipate that our combination will provide a deeper understanding of the underlying roles that contingency and determinism play in shaping evolutionary processes.
description: 8 pages, 4 figures
Spectral action for a one-parameter family of Dirac-type operators on SU(2) and its inflation model
Creators: name: Lai, Alan
name: Teh, Kevin
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mathematical Physics (math-ph)
subject: Representation Theory (math.RT)
subject: Spectral Theory (math.SP)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We analyze the Dirac Laplacian of a one-parameter family of Dirac operators on a compact Lie group, which includes the Levi-Civita, cubic, and trivial Dirac operators. More specifically, we describe the Dirac Laplacian action on any Clifford module in terms of the action of the Lie algebra's Casimir element on finite-dimensional irreducible representations of the Lie group. Using this description of the Dirac Laplacian, we explicitly compute spectrum for the one-parameter family of Dirac Laplacians on SU(2), and then using the Poisson summation formula, the full asymptotic expansion of the spectral action. The technique used to explicitly compute the spectrum applies more generally to any Lie group where one can concretely describe the weights and corresponding irreducible representations, as well as decompose tensor products of an irreducible representation with the Weyl representation into irreducible components. Using the full asymptotic expansion of the spectral action, we generate the inflation potential and slow-roll parameters for the corresponding pure gravity inflationary theory.
description: 9 pages
GOLPE SEM FARDA
Creators: name: Santana, José Cláudio Pavão
Publisher: name: Zenodo - Cadernos da Pena do Pavao
Year: 2023

description: Ano 09 – vol. 07 – n. 54/2021
A Constituição de 1988 precisa deixar de ser chamada de Constituição Federal. Antes da organização do Estado a declaração é de que ela é da República, para, então, dizer que é federativa.
Há muitas razões para esta defesa que não se limitam ao insuficiente argumento da "res publica" – coisa pública. Basta lembrar que na monarquia constitucional os bens são públicos, porque a coroa não é propriedade privada.
BDNF haploinsufficiency induces behavioral endophenotypes of schizophrenia in male mice that are rescued by enriched environment
Creators: name: Harb, Mahmoud
name: Jagusch, Justina
name: Durairaja, Archana
name: Endres, Thomas
name: Leßmann, Volkmar
name: Fendt, Markus
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2021
Subjects: subject: Schizophrenia
subject: Brain-derived neurotrophic factor (BDNF)
subject: 610.72

description: Brain-derived neurotrophic factor (BDNF) is implicated in a number of processes that are crucial for healthy functioning of the brain. Schizophrenia is associated with low BDNF levels in the brain and blood, however, not much is known about BDNF’s role in the different symptoms of schizophrenia. Here, we used BDNF-haploinsufficient (BDNF+/−) mice to investigate the role of BDNF in different mouse behavioral endophenotypes of schizophrenia. Furthermore, we assessed if an enriched environment can prevent the observed changes. In this study, male mature adult wild-type and BDNF+/− mice were tested in mouse paradigms for cognitive flexibility (attentional set shifting), sensorimotor gating (prepulse inhibition), and associative emotional learning (safety and fear conditioning). Before these tests, half of the mice had a 2-month exposure to an enriched environment, including running wheels. After the tests, BDNF brain levels were quantified. BDNF+/− mice had general deficits in the attentional set-shifting task, increased startle magnitudes, and prepulse inhibition deficits. Contextual fear learning was not affected but safety learning was absent. Enriched environment housing completely prevented the observed behavioral deficits in BDNF+/− mice. Notably, the behavioral performance of the mice was negatively correlated with BDNF protein levels. These novel findings strongly suggest that decreased BDNF levels are associated with several behavioral endophenotypes of schizophrenia. Furthermore, an enriched environment increases BDNF protein to wild-type levels and is thereby able to rescue these behavioral endophenotypes.
WKB analysis of relativistic Stern-Gerlach measurements
Creators: name: Palmer, Matthew C.
name: Takahashi, Maki
name: Westman, Hans F.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Spin is an important quantum degree of freedom in relativistic quantum information theory. This paper provides a first-principles derivation of the observable corresponding to a Stern-Gerlach measurement with relativistic particle velocity. The specific mathematical form of the Stern-Gerlach operator is established using the transformation properties of the electromagnetic field. To confirm that this is indeed the correct operator we provide a detailed analysis of the Stern-Gerlach measurement process. We do this by applying a WKB approximation to the minimally coupled Dirac equation describing an interaction between a massive fermion and an electromagnetic field. Making use of the superposition principle we show that the +1 and -1 spin eigenstates of the proposed spin operator are split into separate packets due to the inhomogeneity of the Stern-Gerlach magnetic field. The operator we obtain is dependent on the momentum between particle and Stern-Gerlach apparatus, and is mathematically distinct from two other commonly used operators. The consequences for quantum tomography are considered.
description: 13 pages, no figures. Comments welcome
Additional file 2 of CD9, a potential leukemia stem cell marker, regulates drug resistance and leukemia development in acute myeloid leukemia
Creators: name: Liu, Yongliang
name: Wang, Guiqin
name: Zhang, Jiasi
name: Chen, Xue
name: Xu, Huailong
name: Heng, Gang
name: Chen, Jun
name: Zhao, Yongchun
name: Li, Jiatao
name: Ni, Yuanli
name: Zhang, Yingzi
name: Shan, Juanjuan
name: Qian, Cheng
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 2: Figure S1. Flow cytometry was used to detect the expression of CD9 in AML cell lines. Figure S2. Flow cytometry detects the cell cycle of CD9+ and CD9- cells. *p<0.05, **p<0.01, ***p<0.001. Figure S3. Survival curve of mice transplanted with CD9+ THP-1 cell and CD9- THP-1 cells (n=7) (1X106 cells/mouse). Figure S4. ChIP was used to verify the binding of transcription factor EGR1 to the promoter of CD9. *p<0.05, **p<0.01, ***p<0.001.
Shortening tool setting time for transfer presses
Creators: name: Behrens, Bernd-Arno
name: Doege, E.
name: Krimm, R.
Publisher: name: London : SAGE Publications Ltd.
Year: 2006
Subjects: subject: Set-up time
subject: Tool setting
subject: Transfer presses
subject: Computational methods
subject: Deformation
subject: Geometry
subject: Metal forming
subject: Production engineering
subject: Sheet metal
subject: Machine tools
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau::621 | Angewandte Physik

description: The production processes of sheet metal products with complex geometries often use transfer presses to obtain fully formed workpieces from a single machine. The job of adjusting a new multistage tool set increases with the number of stages because the deformations of the frame, the bottom platen, and the ram vary with the different applied loads. Each of the forces applied by the stages causes a specific deformation of the machine, while each stage is also influenced by all other stages. The Institute for Metal Forming and Metal Forming Machine Tools (University of Hanover, Germany) has developed a new computer-based set-up system for multistage tools. Once the machine properties have been measured, the system calculates the deformation of the machine on the basis of the forming forces measured during the tool setting process. The use of the developed system will help to shorten the first set-up of new tool sets. Manufacturers of sheet metal products are expecting significant time savings. © IMechE 2006.
Gas of wormholes in Euclidean quantum field theory
Creators: name: Savelova, E. P.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We model the spacetime foam picture by a gas of wormholes in Euclidean field theory. It is shown that at large distances the presence of such a gas leads merely to a renormalization of mass and charge values. We also demonstrate that there exist a class of specific distributions of point-like wormholes which essentially change the ultraviolet behavior of Green functions and lead to finite quantum field theories.
description: 11 pages, some misprints removed
Understanding Relationship Marketing Outcomes: An Integration of Relational Benefits and Relationship Quality
Creators: name: Hennig-Thurau, Thorsten
name: Gwinner, Kevin P.
name: Gremler, Dwayne D.
Publisher: name: London : SAGE Publications Ltd.
Year: 2002
Subjects: subject: business models
subject: e-commerce
subject: financial markets
subject: Internet
subject: pricing
subject: Dewey Decimal Classification::600 | Technik::650 | Management

description: The importance of developing and maintaining enduring relationships with customers of service businesses is generally accepted in the marketing literature. A key challenge for researchers is to identify and understand how managerially controlled antecedent variables influence important relationship marketing outcomes (e.g., customer loyalty and word-of-mouth communication). Relational benefits, which have a focus on the benefits consumers receive apart from the core service, and relationship quality, which focuses on the overall nature of the relationship, represent two approaches to understanding customer loyalty and word of mouth. This article integrates these two concepts by positioning customer satisfaction and commitment as relationship quality dimensions that partially mediate the relationship between three relational benefits (confidence benefits, social benefits, and special treatment benefits) and the two outcome variables. The results provide support for the model and indicate that the concepts of customer satisfaction, commitment, confidence benefits, and social benefits serve to significantly contribute to relationship marketing outcomes in services. © 2002, Sage Publications. All rights reserved.
Delay Analysis of Max-Weight Queue Algorithm for Time-varying Wireless Adhoc Networks - Control Theoretical Approach
Creators: name: Chen, Junting
name: Lau, Vincent K. N.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Systems and Control (eess.SY)
subject: Information Theory (cs.IT)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Max weighted queue (MWQ) control policy is a widely used cross-layer control policy that achieves queue stability and a reasonable delay performance. In most of the existing literature, it is assumed that optimal MWQ policy can be obtained instantaneously at every time slot. However, this assumption may be unrealistic in time varying wireless systems, especially when there is no closed-form MWQ solution and iterative algorithms have to be applied to obtain the optimal solution. This paper investigates the convergence behavior and the queue delay performance of the conventional MWQ iterations in which the channel state information (CSI) and queue state information (QSI) are changing in a similar timescale as the algorithm iterations. Our results are established by studying the stochastic stability of an equivalent virtual stochastic dynamic system (VSDS), and an extended Foster-Lyapunov criteria is applied for the stability analysis. We derive a closed form delay bound of the wireless network in terms of the CSI fading rate and the sensitivity of MWQ policy over CSI and QSI. Based on the equivalent VSDS, we propose a novel MWQ iterative algorithm with compensation to improve the tracking performance. We demonstrate that under some mild conditions, the proposed modified MWQ algorithm converges to the optimal MWQ control despite the time-varying CSI and QSI.
description: This paper has been accepted by the IEEE Transactions on Signal Processing
MLPACK: A Scalable C++ Machine Learning Library
Creators: name: Curtin, Ryan R.
name: Cline, James R.
name: Slagle, N. P.
name: March, William B.
name: Ram, Parikshit
name: Mehta, Nishant A.
name: Gray, Alexander G.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mathematical Software (cs.MS)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: MLPACK is a state-of-the-art, scalable, multi-platform C++ machine learning library released in late 2011 offering both a simple, consistent API accessible to novice users and high performance and flexibility to expert users by leveraging modern features of C++. MLPACK provides cutting-edge algorithms whose benchmarks exhibit far better performance than other leading machine learning libraries. MLPACK version 1.0.3, licensed under the LGPL, is available at http://www.mlpack.org.
description: Submitted to JMLR MLOSS (http://jmlr.csail.mit.edu/mloss/)
The financial crisis in the German and English press: Metaphorical structures in the media coverage on Greece, Spain and Italy
Creators: name: Bickes, H.
name: Otten, T.
name: Weymann, L.C.
Publisher: name: London : SAGE Publications Ltd.
Year: 2014
Subjects: subject: Critical discourse analysis
subject: discourse positions
subject: German/English press
subject: Greek/European financial crisis
subject: media coverage
subject: metaphor analysis
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie

description: The German media presentation of the so-called Greek financial crisis caused an unexpected uproar in Germany. An anti-Greek sentiment evolved and spread among German citizens and solidarity for crisis-hit Greece was mostly rejected. Public surveys revealed that many Germans even wanted Greece to exit the Eurozone immediately. This article highlights the crucial role of the media in shaping the negative public opinion. In 2010, a period which has lately been referred to as Greek bashing, the German press had discussed the Greek financial crisis heatedly and controversially. Europe's largest daily newspaper, BILD, published numerous reports that implicitly and explicitly constituted the myth of the corrupt and lazy Greeks in comparison to the hard-working Germans. In 2012, the crisis had spread much further, and not only Greece but other countries too were suffering from high debt, economic stagnation and unemployment. The news coverage became more moderate and conciliating and presented the dramatic social consequences for the respective population. This study highlights not only the development of the German media's tenor on the Greek crisis through time, but adds an international perspective and widens the view by comparing the media treatment of the different countries involved. Based on 122 online articles, the study methodologically focuses on the analysis of metaphorical language in the news coverage of three comparable international news magazines: SPIEGEL (Germany), The Economist (the UK) and TIME (the USA), and contrasts the representation of Greece with the depiction of larger indebted European countries like Spain and Italy. The analysis shows remarkable differences in the evaluation and presentation of the crisis, which can be linked to the degree of involvement of Germany, the UK and the USA in European policies. © The Author(s) 2014.
The Tat-dependent protein translocation pathway
Creators: name: Hou, Bo
name: Brüser, Thomas
Publisher: name: Berlin : De Gruyter
Year: 2011
Subjects: subject: protein folding
subject: protein transport
subject: redox protein biogenesis
subject: twin-arginine translocation
subject: Archaea
subject: Bacteria (microorganisms)
subject: Proteobacteria
subject: Dewey Decimal Classification::500 | Naturwissenschaften

description: The twin-arginine translocation (Tat) pathway is found in bacteria, archaea, and plant chloroplasts, where it is dedicated to the transmembrane transport of fully folded proteins. These proteins contain N-terminal signal peptides with a specific Tat-system binding motif that is recognized by the transport machinery. In contrast to other protein transport systems, the Tat system consists of multiple copies of only two or three usually small (∼8-30 kDa) membrane proteins that oligomerize to two large complexes that transiently interact during translocation. Only one of these complexes includes a polytopic membrane protein, TatC. The other complex consists of TatA. Tat systems of plants, proteobacteria, and several other phyla contain a third component, TatB. TatB is evolutionarily and structurally related to TatA and usually forms tight complexes with TatC. Minimal two-component Tat systems lacking TatB are found in many bacterial and archaeal phyla. They consist of a 'bifunctional' TatA that also covers TatB functionalities, and a TatC. Recent insights into the structure and interactions of the Tat proteins have various important implications. © 2011 by Walter de Gruyter Berlin Boston 2011.
Submillimetre line spectrum of the Seyfert galaxy NGC1068 from the Herschel-SPIRE Fourier Transform Spectrometer
Creators: name: Spinoglio, Luigi
name: Pereira-Santaella, Miguel
name: Busquet, Gemma
name: Schirm, Maximilien R. P.
name: Wilson, Christine D.
name: Glenn, Jason
name: Kamenetzky, Julia
name: Rangwala, Naseem
name: Maloney, Philip R.
name: Parkin, Tara J.
name: Bendo, George J.
name: Madden, Suzanne C.
name: Wolfire, Mark G.
name: Boselli, Alessandro
name: Cooray, Asantha
name: Page, Mathew J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The first complete submillimetre spectrum (190-670um) of the Seyfert 2 galaxy NGC1068 has been observed with the SPIRE Fourier Transform Spectrometer onboard the {\it Herschel} Space Observatory. The sequence of CO lines (Jup=4-13), lines from water, the fundamental rotational transition of HF, two o-H_2O+ lines and one line each from CH+ and OH+ have been detected, together with the two [CI] lines and the [NII]205um line. The observations in both single pointing mode with sparse image sampling and in mapping mode with full image sampling allow us to disentangle two molecular emission components, one due to the compact circum-nuclear disk (CND) and one from the extended region encompassing the star forming ring (SF-ring). Radiative transfer models show that the two CO components are characterized by density of n(H_2)=10^4.5 and 10^2.9 cm^-3 and temperature of T=100K and 127K, respectively. The comparison of the CO line intensities with photodissociation region (PDR) and X-ray dominated region (XDR) models, together with other observational constraints, such as the observed CO surface brightness and the radiation field, indicate that the best explanation for the CO excitation of the CND is an XDR with density of n(H_2) 10^4 cm^-3 and X-ray flux of 9 erg s^-1 cm^-2, consistent with illumination by the active galactic nucleus, while the CO lines in the SF-ring are better modeled by a PDR. The detected water transitions, together with those observed with the \her \sim PACS Spectrometer, can be modeled by an LVG model with low temperature (T_kin \sim 40K) and high density (n(H_2) in the range 10^6.7-10^7.9 cm^-3).
description: Accepted for publication on the Astrophysical Journal, 30 August 2012
ACCESS-Background rate of adverse events-definition –Anosmia & Ageusia
Creators: name: Egbers, T
name: Willame, C
name: Belbachir, L
name: Souverein, P
name: Martín-Pérez, M
name: García-Poza, P
name: Sturkenboom, MCJM
Publisher: name: Zenodo
Year: 2021
Subjects: electronic health care databases, codes, AESI, vaccine, anosmia, ageusia

description: This document contains the definition of Anosmia & Ageusia and the operationalization to extract this event from different electronic health care databases in the EU, to calculate background rates of AESI The document contains the key definition, procedures and treatments, the diagnosis codes based on Codemapper output with changes/additions by data access providers, and when available published validation studies and background rates
description: This study (ACCESS project) was funded by the European Medicines Agency
Asexual Evolution Waves: Fluctuations and Universality
Creators: name: Fisher, Daniel S.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences

description: In large asexual populations, multiple beneficial mutations arise in the population, compete, interfere with each other, and accumulate on the same genome, before any of them fix. The resulting dynamics, although studied by many authors, is still not fully understood, fundamentally because the effects of fluctuations due to the small numbers of the fittest individuals are large even in enormous populations. In this paper, branching processes and various asymptotic methods for analyzing the stochastic dynamics are further developed and used to obtain information on fluctuations, time dependence, and the distributions of sizes of subpopulations, jumps in the mean fitness, and other properties. The focus is on the behavior of a broad class of models: those with a distribution of selective advantages of available beneficial mutations that falls off more rapidly than exponentially. For such distributions, many aspects of the dynamics are universal - quantitatively so for extremely large populations. On the most important time scale that controls coalescent properties and fluctuations of the speed, the dynamics is reduced to a simple stochastic model that couples the peak and the high-fitness "nose" of the fitness distribution. Extensions to other models and distributions of available mutations are discussed briefly.
description: 3 figures
Stimmt das Volumen der Pipette?
Creators: name: Romaguera, Antonio
Publisher: name: Berlin : De Gruyter
Year: 2013
Subjects: subject: Pipette
subject: Luftpolsterpipetten
subject: Kolbenhubpipetten
subject: Dewey Decimal Classification::600 | Technik::660 | Technische Chemie

description: Nahezu jedes Labor nutzt Kolbenhubpipetten mit Luftpolster, im allgemeinen Sprachgebrauch oft als Mikroliterpipetten bezeichnet. Diese sind im Rahmen der Prüfmittelüberwachung regelmäßig zu kalibrieren. Da Faktoren wie Luftfeuchtigkeit und Temperatur die Ergebnisse stark beeinflussen, sind die Prüfbedingungen exakt einzuhalten. Worauf kommt es wirklich an?
Earth-based spectroscopy of Jupiter’s Galilean moons
Creators: name: King, Oliver
Publisher: name: University of Leicester
Year: 2023
Subjects: Uncategorized

description: This thesis uses spatially resolved spectral observations, primarily from the ground based Very Large Telescope (VLT), to model and understand the surface composition of the Galilean moons. Previous studies have proposed various compositional hypotheses, so I developed a Markov Chain Monte Carlo (MCMC) spectral inversion routine which allows detailed investigation of the different compositional mixtures which are consistent with an observed spectrum. I use this MCMC routine to quantify uncertainties on fitted abundances from infrared spectral observations of the icy moons Europa and Ganymede, and quantitatively demonstrate how the hydrated salt mixture on these moons cannot be fully constrained using near-infrared spectroscopy alone. I produced compositional mapping datasets by analysing observations from the VLT/SPHERE, VLT/MUSE and Galileo/NIMS instruments to study the abundances and spatial distributions of ices, volatiles, and contaminants on the surfaces of the Galilean moons. On Europa, I mapped the contrasts between the high acid abundance (∼ 60%) near the trailing apex and high water ice abundances (∼ 50%) at high latitudes, and constrained the possible spatial distributions of hydrated salts. Modelling results for Ganymede were dominated by water ice in younger areas (abundances up to 50%) and a spectrally flat darkening agent in older terrain (up to 60% abundance). The water ice grain size on Ganymede was found to have strong latitudinal and longitudinal contrasts, driven by global scale trends in temperature and plasma bombardment. Mapping of the 590nm SO2 absorption band on Io identified stronger absorptions at mid latitudes and in the Pele ejecta blanket. The 577.3nm O2 band on Ganymede was found to be spatially constrained to the closed magnetic field line region, with the strongest absorptions on the trailing hemisphere. Comparison of the datasets is used to demonstrate how ground-based telescopes can carry out compositional mapping which was previously only possible using spacecraft. These datasets fill spatial and spectral gaps in observations of the moons and will help to prepare and guide the next decade of exploration of these worlds by the JUICE and Europa Clipper spacecraft. I led a successful observing campaign of Ganymede with VLT/SPHERE in 2021, and work from this thesis is published in King et al. (2022) and King and Fletcher (2022).
The minimum moisture threshold for wood decay by basidiomycetes revisited. A review and modified pile experiments with Norway spruce and European beech decayed by Coniophora puteana and Trametes versicolor
Creators: name: Brischke, Christian
name: Soetbeer, Arved
name: Meyer-Veltrup, Linda
Publisher: name: Berlin : De Gruyter
Year: 2017
Subjects: subject: brown rot
subject: durability
subject: fungi
subject: minimum moisture threshold
subject: physiological limit
subject: pile test
subject: white rot
subject: wood decay
subject: wood decay fungi
subject: Durability
subject: Fungi
subject: Moisture
subject: Piles
subject: Plants (botany)
subject: Wood
subject: Brown rot
subject: Pile tests
subject: White rot
subject: Wood-decay fungi
subject: Decay (organic)
subject: Dewey Decimal Classification::600 | Technik::630 | Landwirtschaft, Veterinärmedizin

description: To know the minimum moisture threshold (MMThr) in wood allowing for the initiation of the fungal decay by basidiomycetes is relevant both from a theoretical and a practical point of view. The present work summarizes the knowledge about MMThr and presents experimental data obtained by improved laboratory decay tests on Picea abies (Norway spruce) and Fagus sylvatica (European beech) with the fungi Coniophora puteana and Trametes versicolor under different exposure scenarios well suited for simulation in real applications. The three experimental set-ups, in which the pile tests play a pivotal role, differed in terms of external moisture supply and the inoculation strategies. It was confirmed that wood-destroying basidiomycetes are able to degrade wood at high relative humidity without any external source of available liquid water. The method of moistening the wood samples has an effect on the MMThr before initiation of the fungal decay, but different basidiomycetes were able to cause significant decay at moisture contents considerably below the fiber saturation point. © 2017 Walter de Gruyter GmbH, Berlin/Boston 2017.
The rhodanese RhdA helps Azotobacter vinelandii in maintaining cellular redox balance
Creators: name: Remelli, William
name: Cereda, Angelo
name: Papenbrock, Jutta
name: Forlani, Fabio
name: Pagani, Silvia
Publisher: name: Berlin: Walter de Gruyter
Year: 2010
Subjects: subject: cytochrome bd expression
subject: escherichia-coli
subject: hydrogen-peroxide
subject: mercaptopyruvate sulfurtransferase
subject: pseudomonas-putida
subject: cydr fnr
subject: metabolism
subject: stress
subject: oxyr
subject: thioredoxin
subject: oxidative stress
subject: transcriptomic analyses
subject: Dewey Decimal Classification::500 | Naturwissenschaften::580 | Pflanzen (Botanik)

description: The tandem domain rhodanese-homology protein RhdA of Azotobacter vinelandii shows an active-site loop structure that confers structural peculiarity in the environment of its catalytic cysteine residue. The in vivo effects of the lack of RhdA were investigated using an A. vinelandii mutant strain (MV474) in which the rhdA gene was disrupted by deletion. Here, by combining analytical measurements and transcript profiles, we show that deletion of the rhdA gene generates an oxidative stress condition to which A. vinelandii responds by activating defensive mechanisms. In conditions of growth in the presence of the superoxide generator phenazine methosulfate, a stressor-dependent induction of rhdA gene expression was observed, thus highlighting that RhdA is important for A. vinelandii to sustain oxidative stress. The potential of RhdA to buffer general levels of oxidants in A. vinelandii cells via redox reactions involving its cysteine thiol is discussed.
General law of growth and replication. Growth equation and its applications
Creators: name: Shestopaloff, Yu. K.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Other Quantitative Biology (q-bio.OT)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: We present significantly advanced studies of the previously introduced physical growth mechanism and unite it with biochemical growth factors. Obtained results allowed formulating the general growth law which governs growth and evolutional development of all living organisms, their organs and systems. It was discovered that the growth cycle is predefined by the distribution of nutritional resources between maintenance needs and biomass production. This distribution is quantitatively defined by the growth ratio parameter, which depends on the geometry of an organism, phase of growth and, indirectly, organism's biochemical machinery. The amount of produced biomass, in turn, defines the composition of biochemical reactions. Changing amount of nutrients diverted to biomass production is what forces organisms to proceed through the whole growth and replication cycle. The growth law can be formulated as follows: the rate of growth is proportional to influx of nutrients and growth ratio. Considering specific biochemical components of different organisms, we find influxes of required nutrients and substitute them into the growth equation; then, we compute growth curves for amoeba, wild type fission yeast, fission yeast's mutant. In all cases, predicted growth curves correspond very well to experimental data. Obtained results prove validity and fundamental scientific value of the discovery.
description: 53 pages, 17 figures, 4 tables
The tectono-metamorphic evolution of a dismembered ophiolite (Tinos, Cyclades, Greece)
Creators: name: Katzir, Yaron
name: Matthews, Alan
name: Garfunkel, Zvi
name: Schliestedt, Manfred
name: Avigad, Dov
Publisher: name: Cambridge : Cambridge University Press
Year: 1996
Subjects: subject: Cycladic Massif
subject: Upper Tectonic Unit
subject: Tinos
subject: greenschist facies
subject: obduction
subject: ophiolite
subject: supra subduction zone
subject: tectonic slice
subject: tectonometamorphic evolution
subject: Greece, Cyclades, Tinos
subject: Dewey Decimal Classification::500 | Naturwissenschaften::550 | Geowissenschaften

description: The six exposures of the Upper tectonic Unit of the Cycladic Massif occurring on the island of Tinos are shown to comprise a metamorphosed dismembered ophiolite complex. The common stratigraphic section consisting of tens-of-metres- thick tectonic slices of mafic phyllites overlain by serpentinites and gabbros is considered to have been derived by a combination of thrusting during obduction and subsequent attenuation by low-angle normal faults. All rock types show evidence of a phase of regional greenschist-facies metamorphism, which in the case of the phyllites is accompanied by penetrative deformation. The greenschist-facies metamorphism in gabbros is preceded by high temperature sea-floor amphibolite-facies alteration, whereas in the serpentinites, the antigorite + forsterite greenschist-facies assemblage overprinted an earlier low temperature lizardite serpentinite. Trace element patterns of the mafic phyllites and a harzburgitic origin of meta-serpentinites suggest a supra subduction zone (SSZ) affinity for the ophiolitic suite. δ81O values of phyllites, gabbros and serpentinites range from 6 to 15‰. Model calculations indicate that such values are consistent with low temperature (50-200 °C) alteration of parent rocks by sea-water at varying water/rock ratios. This would agree with the early low temperature mineralogy of the serpentinites, but the early high temperature alteration of the gabbros would require the presence of 18O-enriched sea-water. The following overall history is suggested for Tinos ophiolitic slices. (1) Oceanic crust was generated at a supra-subduction zone spreading centre with high temperature alteration of gabbros. (2) Tectonic disturbance (its early hot stages recorded in an amphibolitic shear zone at the base of serpentinites) brought the already cooled ultramafics into direct contact with sea-water and caused low-T serpentinization. (3) Tectonism after cooling involved thrusting which caused repetition and inversion of the original order of the oceanic suite. (4) Regional metamorphism of all the ophiolite components at greenschist-facies conditions (∼450 °C) overprinted the early alteration mineralogy. It was probably induced by continued thrusting and piling up of nappes. The Tinos ophiolite, dated as late Cretaceous and genetically related to other low pressure rock-units of the same age in the Aegean, differs in age and degree of dismemberment and metamorphism from ophiolites in mainland Greece.
Produced in Salinas: The Manifestation of Mexican Field Work Labor Disposability
Creators: name: Isarraras, Virginia
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: subject: Labor
subject: Exploitation
subject: Agricultural laborers

description: In capitalist U.S society, Mexican bodies, and Latine bodies more broadly, are dehumanized and reduced to their economic productivity, specifically in the context of agricultural work. Human beings are both consciously and unconsciously viewed as interchangeable parts of a production system. Latine individuals make up 92% of the field working population, 72% of whom are undocumented, and the vast majority are of Mexican descent (CRE, 2013). These racialized bodies are exploited for their labor and are not properly compensated due to their limited legal protection. While this phenomenon affects Latine individuals, I will focus on its construction and manifestation among Mexican descent individuals.
The Shapes of the HI Velocity Profiles of the THINGS Galaxies
Creators: name: Ianjamasimanana, R.
name: de Blok, W. J. G.
name: Walter, Fabian
name: Heald, George H.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We analyze the shapes of the HI velocity profiles of The HI Nearby Galaxy Survey (THINGS) to study the phase structure of the neutral interstellar medium (ISM) and its relation to global galaxy properties. We use a method analogous to the stacking method sometimes used in high redshift HI observations to construct high signal-to-noise (S/N) profiles. We call these high S/N profiles super profiles. We analyze and discuss possible systematics that may change the observed shapes of the super profiles. After quantifying these effects and selecting a sub-sample of unaffected galaxies, we find that the super profiles are best described by a narrow and a broad Gaussian component, which are evidence of the presence of the Cold Neutral Medium (CNM) and the Warm Neutral Medium (WNM). The velocity dispersion of the narrow component range from ~3.4 to ~8.6 km/s with an average of 6.5+/-1.5 km/s, whereas that of the broad component range from ~10.1 to ~24.3 km/s with an average of 16.8+/-4.3 km/s. We find that the super profile parameters correlate with star formation indicators such as metallicity, FUV-NUV colors and H_alpha luminosities. The flux ratio between the narrow and broad components tends to be highest for high metallicity, high star formation rate (SFR) galaxies. We show that the narrow component identified in the super profiles is associated with the presence of star formation, and possibly with molecular hydrogen.
description: Accepted for publication in the Astronomical Journal, 37 pages, 27 figures, 8 table
Symplectic structures on nilmanifolds: an obstruction for its existence
Creators: name: del Barco, Viviana J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Rings and Algebras (math.RA)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 17B30 17B56 55T05 53D05

description: In this work we introduce an obstruction for the existence of symplectic structures on nilpotent Lie algebras. Indeed, a necessary condition is presented in terms of the cohomology of the Lie algebra. Using this obstruction we obtain both positive and negative results on the existence of symplectic structures on a large family of nilpotent Lie algebras. Namely the family of nilradicals of minimal parabolic subalgebras associated to the real split Lie algebra of classical complex simple Lie algebras.
description: 19 pages
Utilization of the microwave electric or magnetic field in the synthesis of monometallic and bimetallic nanoparticles
Creators: name: Sumi, Takuya
name: Dillert, Ralf
name: Horikoshi, Satoshi
Publisher: name: Cambridge : Royal Society of Chemistry
Year: 2015
Subjects: subject: nanoparticles
subject: Ag
subject: Ag–Ni
subject: Pd–Ag
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: The wet synthesis of mono-disperse Ag, Ag–Ni, and Pd–Ag nanoparticles has been performed employing glycol solutions containing [Ag(NH3)2]+ and a second metal cation Mn+ (M = Ag, Na, Al, Ni or Pd) under microwave irradiation in a predominately electric (E-) or a predominately magnetic (H-) field. No specific effects of the microwave E-field and H-field on the rate of product formation have been observed. But the synthesis of Ag–Ni alloy particles in the E-field and the H-field resulted in products with different particle size distribution, thus possibly indicating specific field effects.