cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Traumatisiert durch Intersex-Genitalverstümmelung?
Creators: name: Frauenfelder, Leonie
name: Imhof, Andrina
Publisher: name: Berner Fachhochschule - Soziale Arbeit
Year: 2022
Subjects: Intersexualität
Trauma

description: In der vorliegenden Bachelor-Thesis bearbeiten wir die folgende Fragestellung: Welche Schlussfolgerungen können aus der Psychotraumatologie gezogen werden für die Betroffenen von “geschlechtszuweisenden Eingriffen an Kindern mit Variationen der Geschlechtsentwicklung ohne medizinische Notwendigkeit” (GEKO)? Zur Beantwortung dieser Frage setzen wir uns mit interdisziplinärem Grundlagenwissen über GEKO als Literaturarbeit auseinander. Der Schwerpunkt liegt dabei auf der Analyse des medizinischen Diskurses und den politischen Haltungen zu den potenziellen Menschenrechtsverletzungen. Dabei fokussieren wir den deutschsprachigen Raum, aber nehmen auch eine globale Perspektive ein. Abschliessend stellen wir in diesem ersten Theorieteil ein Fallbeispiel und Behandlungserfahrungen vor, um die Perspektive betroffener Personen einfliessen zu lassen. In einem weiteren theoretischen Teil legen wir relevante Grundlagen der Psychotraumatologie dar für die potenziell traumatische Situation GEKO. Wir legen die Entwicklung dieses Gebietes der Psychologie dar und betrachten dabei auch die Zukunftsaussichten. Wir berücksichtigen unterschiedliche Formen und Verständnisse von Traumata. Der Kernteil unserer Arbeit verfolgt das Ziel, GEKO als potenziell traumatische Situation einzuordnen. Damit wollen wir die Relevanz der Erforschung dieses spezifischen Ereignisses und seinen möglichen Auswirkungen aufzuzeigen. Wir betrachten Entwicklungssequenzen von Kindern, aus welchen wir altersspezifische Herausforderungen für GEKO-Betroffene ableiten. Dies ist wichtig, da Traumata als multifaktorielle Prozesse beurteilt werden sollen. Wir versuchen das sequenzielle Traumakonzept von Keilson anzuwenden. Aufgrund der mangelnden empirischen Datengrundlage zu GEKO ist dieser Versuch gescheitert. Weiter stellen wir Schutz- und Risikofaktoren vor, welche sich auf den potenziell traumatischen Prozess auswirken können und Anhaltspunkte auf wichtige zu erschliessende Ressourcen liefern, wie beispielsweise eine sichere Bindung. Im letzten Teil der Arbeit wenden wir uns den Implikationen für die Praxis und dem Bedarf an trans- und interdisziplinärer Zusammenarbeit zu. Den Fokus legen wir dabei auf die kritische Soziale Arbeit. Dazu leiten wir aus dem Professionsverständnis die Aufgaben der Sozialen Arbeit zur Prävention von GEKO und allfälligen daraus resultierenden Traumata ab. Die Einführung weiterer Personenstandsregister-Einträge neben männlich und weiblich ist ein Beispiel dazu. Als Menschenrechtsprofession ist die Soziale Arbeit dazu verpflichtet, den vorliegenden Vorwürfen der sogenannten “Intersex-Genitalverstümmelung” nachzugehen.
Human error identification and risk prioritization in LPG unloading operations
Creators: name: Virdi, Prabhjot Singh
name: Pamnani, Gulab
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Mental Health

description: Objectives. Errors due to human activities in any operation are analyzed using human reliability analysis in which the principal step is to identify potential human errors followed by quantification and analysis of the error. This work intends to apply a methodology for identifying human errors and to prioritize the risk associated with them in a liquefied petroleum gas (LPG) unloading operation. Methods. The methodology uses hierarchical task analysis which provides the basic framework, along with a systematic human error reduction and prediction approach which aids in identification and categorization of the errors associated with each task with the help of predefined error taxonomy. Also, in order to quantify the risk associated with each identified error, fuzzy failure mode and effect analysis has been adopted. To rank and prioritize the risk associated with each identified error where the individual constituent components are non-commensurable in nature, the VIseKriterijumska Optimizacija I Kompromisno Resenje method has been incorporated. Results and conclusions. Applicability of the methodology presented will help comprehend the severity of risk corresponding to each error at different levels, and the ranking mechanism thus developed in this work aids to prioritize the action to minimize the likelihood of errors.
On acylindrical hyperbolicity of groups with positive first $\ell^2$-Betti number
Creators: name: Osin, D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Group Theory (math.GR)
subject: Geometric Topology (math.GT)
subject: Operator Algebras (math.OA)
subject: FOS: Mathematics

description: We prove that every finitely presented group with positive first $\ell^2$-Betti number that virtually surjects onto $\mathbb Z$ is acylindrically hyperbolic. In particular, this implies acylindrical hyperbolicity of finitely presented residually finite groups with positive first $\ell^2$-Betti number as well as groups of deficiency at least $2$.
description: The published version of this paper used a result from arXiv:1310.6289 whose proof contained a gap. The gap and necessary changes to the published version of this paper are discussed in arXiv:1711.09486. This version incorporates these changes
Response of Pseudomonas aeruginosa to pyocyanin: mechanisms of resistance, antioxidant defenses, and demonstration of a manganese-cofactored superoxide dismutase.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1992

description: Pseudomonas aeruginosa produces a blue pigment, pyocyanin. Pyocyanin is a redox-active phenazine compound that kills mammalian and bacterial cells through the generation of reactive oxygen intermediates. We examined the mechanisms by which P. aeruginosa resists pyocyanin. [14C]pyocyanin was taken up by both Escherichia coli and P. aeruginosa, though more slowly by the latter. Cyanide-insensitive respiration, used as an indicator of intracellular superoxide and/or hydrogen peroxide production, was 50-fold less in pyocyanin-treated P. aeruginosa than in E. coli. P. aeruginosa showed less cyanide-insensitive respiration than E. coli upon exposure to other redox-active compounds (paraquat, streptonigrin, and plumbagin). Electron paramagnetic resonance spectrometry and spin trapping showed that P. aeruginosa generated less pyocyanin radical and superoxide than E. coli. Cell extracts from E. coli contained an NADPH:pyocyanin oxidoreductase which increased the rate of reduction of pyocyanin by NADPH. Conversely, cell extracts from P. aeruginosa contained no NADPH:pyocyanin oxidoreductase activity and actually decreased the rate of pyocyanin-mediated NADPH oxidation. Antioxidant defenses could also reduce the sensitivity of P. aeruginosa to pyocyanin. Under culture conditions of limited phosphate, both pyocyanin production and catalase activity were enhanced. Superoxide dismutase activity was also increased under low-phosphate conditions. When cells were grown in a high-phosphate succinate medium, P. aeruginosa formed a previously described iron-superoxide dismutase as well as a manganese-cofactored superoxide dismutase. These results demonstrate that P. aeruginosa resists pyocyanin because of limited redox cycling of this compound and that under conditions favoring pyocyanin production, catalase and superoxide dismutase activities increase.
A study of the concept and practice of project financing in UK-based banks
Creators: name: Gill, Christopher P.
Publisher: name: Loughborough University
Year: 2020
Subjects: subject: 150399 Business and Management not elsewhere classified
subject: FOS: Economics and business

description: The thesis reports the results of an exploratory study designed to examine and clarify the concept and practice of project financing within the UK banking industry and with particular reference to the petroleum and minerals industries. The specific objectives of the research were: (a) to determine exactly what is meant by the term project financing; (b) to identify the motives of both borrowers and banks in using project financing; (c) to examine and assess the practices of banks when evaluating and arranging project financing deals. [Continues.]
Community detection in temporal multilayer networks, with an application to correlation networks
Creators: name: Bazzi, Marya
name: Porter, Mason A.
name: Williams, Stacy
name: McDonald, Mark
name: Fenn, Daniel J.
name: Howison, Sam D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Statistical Finance (q-fin.ST)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Economics and business

description: Networks are a convenient way to represent complex systems of interacting entities. Many networks contain "communities" of nodes that are more densely connected to each other than to nodes in the rest of the network. In this paper, we investigate the detection of communities in temporal networks represented as multilayer networks. As a focal example, we study time-dependent financial-asset correlation networks. We first argue that the use of the "modularity" quality function---which is defined by comparing edge weights in an observed network to expected edge weights in a "null network"---is application-dependent. We differentiate between "null networks" and "null models" in our discussion of modularity maximization, and we highlight that the same null network can correspond to different null models. We then investigate a multilayer modularity-maximization problem to identify communities in temporal networks. Our multilayer analysis only depends on the form of the maximization problem and not on the specific quality function that one chooses. We introduce a diagnostic to measure \emph{persistence} of community structure in a multilayer network partition. We prove several results that describe how the multilayer maximization problem measures a trade-off between static community structure within layers and larger values of persistence across layers. We also discuss some computational issues that the popular "Louvain" heuristic faces with temporal multilayer networks and suggest ways to mitigate them.
description: 42 pages, many figures, final accepted version before typesetting
Additional file 6 of Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis
Creators: name: Schroeter, Christina B.
name: Rolfes, Leoni
name: Gothan, K. S. Sophie
name: Gruchot, Joel
name: Herrmann, Alexander M.
name: Bock, Stefanie
name: Fazio, Luca
name: Henes, Antonia
name: Narayanan, Venu
name: Pfeuffer, Steffen
name: Nelke, Christopher
name: Räuber, Saskia
name: Huntemann, Niklas
name: Duarte-Silva, Eduardo
name: Dobelmann, Vera
name: Hundehege, Petra
name: Wiendl, Heinz
name: Raba, Katharina
name: Küry, Patrick
name: Kremer, David
name: Ruck, Tobias
name: Müntefering, Thomas
name: Budde, Thomas
name: Cerina, Manuela
name: Meuth, Sven G.
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 6: Figure S6. Migration assay of leukocytes in organ cultures of spleens from naïve wild-type mice, with and without cladribine treatment in vitro. A: Migration ratios (number of migrated cells: total cell count) of viable (live), CD4+ or CD8+ T cells and B cells upon cladribine treatment (vehicle (migration) versus cladribine 0.1 µM (migration)) (n = 6 for both vehicle and cladribine treatment, two-way ANOVAs, p-values > 0.05). B: Flow cytometric analysis of the immune cell distribution in % in spleens (vehicle or cladribine (organ)) and the migrated immune cells (vehicle or cladribine (migration)) (n = 6 for both vehicle and cladribine treatment, two-way ANOVAs). C: Mean fluorescence intensities (MFIs) of migration and activation markers in viable CD4+ cells still located in the respective spleen (vehicle or cladribine (organ)) compared to those after egress (vehicle or cladribine ((migration)) (n = 6 for both vehicle and cladribine treatment, two-way ANOVAs). D: MFIs of migration and activation markers in viable CD8+ cells still located in the respective spleen (vehicle or cladribine (organ)) compared to those after egress (vehicle or cladribine ((migration)) (n = 6 for both vehicle and cladribine treatment, two-way ANOVAs, p-values > 0.05). E: MFIs of migration and activation markers in viable B cells still located in the respective spleen (vehicle or cladribine (organ)) compared to those after egress (vehicle or cladribine ((migration)) (n = 6 for both vehicle and cladribine treatment, two-way ANOVAs). p > 0.05 = ns, p < 0.05 = *, p < 0.01 = **, p < 0.001 = ***, p < 0.0001 = ****.
Eschentriebsterben III- Vorläufige Handlungsempfehlungen; Waldschutzinfo Nr. 07 / 2009
Creators: name: Langer, Gitta Jutta
name: Bressem, Ulrich
name: Habermann, Michael
Publisher: name: Zenodo
Year: 2009
Subjects: Eschentriebsterben; ash dieback; Chalara fraxinea

description: Basierend auf den ersten Ergebnissen der von der NW-FVA durchgeführten Meldebogen-Aktion zum Eschentriebsterben (ETS) und eigenen Untersuchungen sowie dem neuesten wissenschaftlichen Kenntnisstand werden im Folgenden weitere Informationen und vorläufige Handlungsempfehlungen zum Eschentriebsterben, verursacht durch den Schlauchpilz (Ascomycota) Hymenoscyphus albidus (Weißes Stengelbecherchen), Nebenfruchtform: Chalara fraxinea, gegeben.
Programmable Multistable 3D Printed Perforated Shellular
Creators: Shi, J.
Mofatteh, H.
Mirabolghasemi, A.
Shahryari, B.
Desharnais, G.
Akbarzadeh, A.H.
Publisher: name: University of Alberta Library
Year: 2022

Conference abstract. Part of the Proceedings of the Canadian Society for Mechanical Engineering International Congress 2022.
Bacterial cell wall polymers (peptidoglycan-polysaccharide) cause reactivation of arthritis.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Intraperitoneal (i.p.) injection of peptidoglycan-polysaccharide derived from group A streptococci (PG-APS) causes chronic arthritis with spontaneous remissions and exacerbations. We hypothesized that, following i.p. injection, PG-APS released from hepatic stores mediated spontaneous recurrences of arthritis. We tested whether transplanted livers with large amounts of PG-APS were able to reactivate quiescent arthritis. Saline-loaded (group 1) or PG-APS-loaded (group 2) livers were transplanted into rats which had been injected intra-articularly 10 days earlier with PG-APS in one joint and saline in the other. A comparison was made with the arthritis that occurred in rats injected i.p. with PG-APS which did not receive transplants (group 3). Arthritis was monitored by serial measurement of joint diameters. Transplantation of saline-loaded livers (group 1) caused no reactivation of arthritis. However, transplantation of PG-APS-loaded livers (group 2) reactivated arthritis (P < 0.0001). Injection of PG-APS i.p. (group 3) induced the most-severe arthritis. PG-APS levels in plasma decreased with time, and PG-APS accumulated in the spleen in groups 2 and 3. Plasma and hepatic levels of PG-APS in rats injected i.p. with PG-APS were greater than levels in rats transplanted with PG-APS-loaded livers, which in turn were greater than levels in rats with saline-loaded livers. Plasma tumor necrosis factor did not correlate with recurrence of arthritis. Transplantation with PG-APS-loaded livers induced reactivation of arthritis in preinjured joints. The extent of arthritis was proportional to hepatic PG-APS content. Reactivation of arthritis may be mediated by slow release of liver-sequestered PG-APS or cytokines (not tumor necrosis factor) released by the liver.
Special birational transformations of type (2,1)
Creators: name: Fu, Baohua
name: Hwang, Jun-Muk
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: A birational transformation f: P^n --> Z, where Z is a nonsingular variety of Picard number 1, is called a special birational transformation of type (a, b) if f is given by a linear system of degree a, its inverse is given by a linear system of degree b and the base locus S \subset P^n of f is irreducible and nonsingular. In this paper, we classify special birational transformations of type (2,1). In addition to previous works Alzati-Sierra and Russo on this topic, our proof employs natural C^*-actions on Z in a crucial way. These C^*-actions also relate our result to the problem studied in our previous work on smooth projective varieties with nonzero prolongations.
description: Minor corrections, final version
Changes in inflammatory mediators in experimental periodontitis in the rhesus monkey.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Ligature-induced periodontitis was monitored for 6 months in eight Macaca mulatta monkeys to examine clinical status, radiographic bone level, and crevicular fluid (CF) levels of prostaglandin E2 (PGE2), thromboxane B2 (TxB2), interleukin-1 beta (IL-1 beta), tumor necrosis factor alpha, and leukotriene B4 (LTB4). A split-mouth design was used, with eight ligated teeth and eight contralateral nonligated teeth which develop soft-chow-promoted (spontaneous) disease. Ligated sites experienced an average attachment loss of 0.94 mm per site and linear bone loss of 0.88 mm per site, with spontaneous-periodontitis sites experiencing approximately half the loss of ligated sites. The CF mediator levels showed increased levels of PGE2 and TxB2 at the ligated sites, as compared with the spontaneous sites, with no significant contralateral differences in the IL-1 beta or LTB4 responses. The concentrations of LTB4 in CF reached an early threefold peak over the baseline level at 1 month. By 2 months there was a statistically significant threefold elevation in CF-PGE2 in the ligated sites and a twofold elevation in the spontaneous sites as compared to the baseline level (P = 0.041 and 0.008, respectively). The monocyte product IL-1 beta increased sharply at 2 months and returned to the baseline level by 6 months at both ligated and nonligated sites. Tumor necrosis factor alpha in CF was below the limit of detection at all sites throughout the experiment (i.e., < 2 ng/ml). The selective elevation of both PGE2 and TxB2 in ligated sites, compared with levels in spontaneous sites, in the presence of similar levels of LTB4 and IL-1 beta provides further evidence that these molecules regulate the magnitude of the tissue-destructive response in progressive periodontitis.
Navigating the Space of Symmetric CMC Surfaces
Creators: name: Heller, Lynn
name: Heller, Sebastian
name: Schmitt, Nicholas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53A10, 53C42, 53C43

description: In this paper we introduce a flow on the spectral data for symmetric CMC surfaces in the $3$-sphere. The flow is designed in such a way that it changes the topology but fixes the intrinsic (metric) and certain extrinsic (periods) closing conditions of the CMC surfaces. For rational times we obtain closed (possibly branched) connected CMC surfaces of higher genus. We prove the short time existence of this flow near the spectral data of (a class of) CMC tori. In particular we prove that flowing the spectral data for the Clifford torus is equivalent to the flow of Plateau solutions by varying the angle of the fundamental piece in Lawson's construction for the minimal surfaces $ξ_{g,1}.$
description: 43 pages, 4 figures, accepted for publication in J. Differential Geo
Additional file 7 of Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis
Creators: name: Schroeter, Christina B.
name: Rolfes, Leoni
name: Gothan, K. S. Sophie
name: Gruchot, Joel
name: Herrmann, Alexander M.
name: Bock, Stefanie
name: Fazio, Luca
name: Henes, Antonia
name: Narayanan, Venu
name: Pfeuffer, Steffen
name: Nelke, Christopher
name: Räuber, Saskia
name: Huntemann, Niklas
name: Duarte-Silva, Eduardo
name: Dobelmann, Vera
name: Hundehege, Petra
name: Wiendl, Heinz
name: Raba, Katharina
name: Küry, Patrick
name: Kremer, David
name: Ruck, Tobias
name: Müntefering, Thomas
name: Budde, Thomas
name: Cerina, Manuela
name: Meuth, Sven G.
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 7: Figure S7. Proliferation assay of splenocytes from naïve wild-type mice, with and without cladribine treatment in vitro. A: Proliferated cells in % after cladribine treatment (with 0.1 or 1 μM cladribine) versus vehicle-treated cells. We compared the unstimulated to the stimulated setting (stimulated with 1 μg/mL anti-CD3 and 2 μg/mL anti-CD28 for 3 days) (n = 6 for both vehicle and cladribine treatment, two-way ANOVAs). B: Mean fluorescence intensities (MFIs) of migration and activation markers in all viable stimulated cells upon vehicle- compared to cladribine-treatment (n = 6 for both vehicle and cladribine treatment, two-way ANOVAs). p > 0.05 = ns, p < 0.05 = *, p < 0.001 = ***, p < 0.0001 = ****.
Generation and purification of recombinant fimbrillin from Porphyromonas (Bacteroides) gingivalis 381.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Fimbrillin is the major subunit protein of fimbriae from the human periodontal pathogen Porphyromonas (Bacteroides) gingivalis. We describe here the generation and initial characterization of recombinant fimbrillin (r-fimbrillin) isolated from P. gingivalis 381. A fragment of DNA encoding the gene for fimbrillin was generated by polymerase chain reaction and cloned into the expression vector pET11b. Plasmids containing the recombinant gene were transfected into Escherichia coli. Clones were selected on plates for ampicillin resistance and individually screened by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) for protein production after activation with IPTG (isopropyl-beta-D- thiogalactopyranoside). One clone, OW0.2, produced significant amounts of a 42-kDa protein after induction with IPTG. This clone contained the pET11b plasmid with a 1-kb insert that had sequence homology to the gene encoding fimbrillin. The majority of recombinant protein from clone OW0.2 was found in the cytoplasm within inclusion bodies. Protein aggregates were solubilized in 8 M urea, and SDS-PAGE analysis showed two major protein bands, one at 42 kDa and the other at 17 kDa. These two proteins coeluted from a DEAE-Sepharose column at 0.15 M NaCl and were reactive to rabbit antiserum to fimbrillin in a Western blot (immunoblot). A preparation giving a single protein band at 42 kDa in SDS-PAGE was obtained by size fractionation by using continuous-elution electrophoresis. Lymph node cells from animals immunized with either fimbrillin from P. gingivalis or r-fimbrillin showed antigen-specific proliferation to both P. gingivalis fimbrillin and r-fimbrillin in an in vitro recall assay. Therefore, it appears that r-fimbrillin is chemically, antigenically, and serologically identical to fimbrillin isolated from P. gingivalis 381.
"example_code.py" of "Search for an anomalous excess of inclusive charged-current $\nu_e$ interactions in the MicroBooNE experiment using Wire-Cell reconstruction"
Creators: name: MicroBooNE Collaboration
Publisher: name: HEPData
Year: 2021

description: Example code for plotting unconstrained and constrained $\nu_e$CC FC
description: Data release for the first results from MicroBooNE's inclusive $\nu_e$CC search using Wire-Cell reconstruction, corresponding to information from arXiv:2110.13978. Attached is a python script which shows an example of how to use this data release to plot the unconstrained and constrained $\nu_e$CC FC data and predictions.
Phlogistic properties of peptidoglycan-polysaccharide polymers from cell walls of pathogenic and normal-flora bacteria which colonize humans.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: PG-PS polymers which can induce experimental chronic inflammation in joints and other tissues can be isolated from the cell walls of human pathogens, such as group A streptococci, as well as from certain indigenous bacterial species which colonize the human intestinal tract. The structural and biological properties that are required for cell wall fragments to express this remarkable activity are still not well defined, but polymer size, resistance to tissue enzymes, and capacity to sustain activation of complement, macrophages, neutrophils, and T cells are properties associated with the most active preparations. There is increasing evidence that PG-PS structures with arthropathogenic activity occur in the human intestinal lumen and that these polymers can be translocated systemically. These observations support the concept that PG-PS, derived from a variety of bacterial species, can be part of the etiology of rheumatoid arthritis and other chronic inflammatory diseases. Since the PG component provides a common element to which all individuals are exposed, it follows that susceptibility is related to efficiency of disposal of bacterial cell wall debris, as well as to cytokine networks and immune cell function (51).
L'ESSERE DISUMANO. IL DA-SEIN NEI 'BEITR�GE ZUR PHILOSOPHIE' DI HEIDEGGER.
Creators: name: BIANCHIN, LUCA
Publisher: name: Universit� degli Studi di Milano
Year: 2020

description: My thesis aims to detect the role of Da-sein in Heidegger?s Beitr�ge zur Philosophie and shows how this should be understood as a new concept compared to the notion of Dasein presented in Sein und Zeit. I claim that Da-sein is not Dasein: these two notions involve two meanings and two different ontological accounts. In order to prove that, in the first chapter I analyse the characteristics of Dasein in Sein und Zeit, so arguing that Dasein and the human beings are two interchangeable terms: Dasein does not indicate the way of being of the human being, rather the human being as a being. Then, I use Heidegger?s works written before Beitr�ge in order to analyse the genesis of Da-sein and, at the same time, the genesis of all the other concepts required to understand its features. In so doing, I isolate three main philosophical domains that, in my opinion, characterise Heidegger?s thought during the early 1930s: the Greeks (second chapter), Nietzsche (third chapter) and H�lderlin (fourth chapter). Through his analysis of Greek philosophy (especially through the analysis of the concepts of physis, aletheia and logos), Heidegger puts the basis to elaborate a new ontology, grounded on the Being (Seyn) as such, and not on that being which questions the meaning of Being (Sein), namely Dasein. Thanks to Nietzsche, Heidegger starts conceiving the end of Western metaphysics and the role of the subject in it. As a consequence, Heidegger argues that the structure of history is ontologically oriented and that the metaphysical subject lies on the opposite side of Da-sein. Finally, by reading H�lderlin Heidegger acquires the philosophical instruments to think beyond this end and beyond this subject; that is, he offers the theoretical tools to understand the necessity of the withdrawal of Being and to locate the human being within this necessity. Therefore, in the fifth chapter, I analyse Beitr�ge on the light of all these theorical frames, gathering them around the problem of Da-sein. In so doing, I show that Da-sein 1) does not indicate the human being, but an ontological place (Ort) that has to be occupied by human being; 2) this place is where Seyn allows human being to ground the being; 3) in metaphysics, this place is closed and the human finds itself outside the Da-sein and it could not properly ground the being; 4) after the end of metaphysics, we have the chance to open again this place, understanding the reasons of its closing, and to situate the human being in the Da-sein.
MOESM1 of Three-dimensional assessment of coronary high-intensity plaques with T1-weighted cardiovascular magnetic resonance imaging to predict periprocedural myocardial injury after elective percutaneous coronary intervention
Creators: name: Hosoda, Hayato
name: Asaumi, Yasuhide
name: Noguchi, Teruo
name: Morita, Yoshiaki
name: Kataoka, Yu
name: Fumiyuki Otsuka
name: Nakao, Kazuhiro
name: Fujino, Masashi
name: Nagai, Toshiyuki
name: Michikazu Nakai
name: Nishimura, Kunihiro
name: Kono, Atsushi
name: Komori, Yoshiaki
name: Hoshi, Tomoya
name: Sato, Akira
name: Kawasaki, Tomohiro
name: Izumi, Chisato
name: Kusano, Kengo
name: Fukuda, Tetsuya
name: Yasuda, Satoshi
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Supplemental Methods, Tables, and Figures. Table S1. Lesion Characteristics on Coronary CTA. Table S2. Receiver Operating Characteristic Analysis Demonstrating the Prediction of pMI using 3Di-PMR and Coronary CTA Variables. Table S3. Lesion Characteristics Categorized by 2D-PMR and 3Di-PMR Cutoffs. Figure S1. Step 1 algorithm for 3-dimensional assessment of coronary plaque (3D Region-growing technique). Figure S2-a. Step 2 algorithm. b. vessel diameter and plaque segmentation. Figure S3. Step 3 algorithm. Figure S4. Troponin T levels before and after PCI in (A) patients without pMI and (B) those with pMI. (C) Relationship between 2D-PMR and 3Di-PMR on T1w imaging. (D, E) Incidence of pMI (A) and slow flow by 3Di-PMR cutoff value.
The immunodominant 90-kilodalton protein is localized on the terminal tip structure of Mycoplasma pneumoniae.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Immunoblot analysis of convalescent-phase sera of experimentally infected chimpanzees or monoclonal antibodies (MAbs) specific to the 90- and 40-kDa proteins of Mycophasma pneumoniae indicated that both proteins were present in cytadsorbing, pathogenic strains PI-1428, M129, and FH but absent in noncytadsorbing, nonpathogenic strain M129-B176. Adsorption of convalescent-phase chimpanzee sera with virulent strain PI-1428 removed reactivity, whereas adsorption with avirulent strain M129-B176 did not remove reactivity to these two proteins. By using proteolysis and specific MAbs, we demonstrated that the 90- and 40-kDa proteins were surface exposed. Immunoelectron microscopy employing specific MAbs showed that the 90-kDa protein is localized on the terminal tip attachment apparatus.Immunoblot analysis of convalescent-phase sera of experimentally infected chimpanzees or monoclonal antibodies (MAbs) specific to the 90- and 40-kDa proteins of Mycophasma pneumoniae indicated that both proteins were present in cytadsorbing, pathogenic strains PI-1428, M129, and FH but absent in noncytadsorbing, nonpathogenic strain M129-B176. Adsorption of convalescent-phase chimpanzee sera with virulent strain PI-1428 removed reactivity, whereas adsorption with avirulent strain M129-B176 did not remove reactivity to these two proteins. By using proteolysis and specific MAbs, we demonstrated that the 90- and 40-kDa proteins were surface exposed. Immunoelectron microscopy employing specific MAbs showed that the 90-kDa protein is localized on the terminal tip attachment apparatus.
The center of ${\mathcal U}_q({\mathfrak n}_ω)$
Creators: name: Jakobsen, Hans Plesner
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: Primary: 17B37, 17A45, 13F60 Secondary: 20G42, 16T20

description: We determine the center of a localization of ${\mathcal U}_q({\mathfrak n}_ω)\subseteq {\mathcal U}^+_q({\mathfrak g})$ by the covariant elements (non-mutable elements) by means of constructions and results from quantum cluster algebras. In our set-up, ${\mathfrak g}$ is any finite-dimensional complex Lie algebra and $ω$ is any element in the Weyl group $W$. The non-zero complex parameter $q$ is mostly assumed not to be a root of unity, but our method also gives many details in case $q$ is a primitive root of unity. We point to a new and very useful direction of approach to a general set of problems which we exemplify here by obtaining the result that the center is determined by the null space of $1+ω$. Further, we use this to give a generalization to double Schubert Cell algebras where the center is proved to be given by $ω^{\mathfrak a}+ω^{\mathfrak c}$. Another family of quadratic algebras is also considered and the centers determined.
description: 28 pages LaTeX. Relevant references as well as a new section relating to the root-of-unity case have been added. Now in print with minor changes
The RTX cytotoxin-related FrpA protein of Neisseria meningitidis is secreted extracellularly by meningococci and by HlyBD+ Escherichia coli.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Neisseria meningitidis produces proteins (FrpA and FrpC) related to he RTX cytotoxin family. In meningococcal strain FAM20 these proteins were both localized in the outer membrane and secreted into the extracellular medium. An Escherichia coli strain with wild-type hemolysin secretion genes hlyB and hlyD and containing a cloned frpA gene secreted FrpA, whereas an isogenic hlyBD mutant strain did not. Low-stringency DNA hybridization revealed hlyBD-like sequences in N. meningitidis FAM20, suggesting that a similar RTX secretion system exists in meningococci.Neisseria meningitidis produces proteins (FrpA and FrpC) related to he RTX cytotoxin family. In meningococcal strain FAM20 these proteins were both localized in the outer membrane and secreted into the extracellular medium. An Escherichia coli strain with wild-type hemolysin secretion genes hlyB and hlyD and containing a cloned frpA gene secreted FrpA, whereas an isogenic hlyBD mutant strain did not. Low-stringency DNA hybridization revealed hlyBD-like sequences in N. meningitidis FAM20, suggesting that a similar RTX secretion system exists in meningococci.
The Determination of Fluoride in Milk and Milk Products
Creators: name: Smith, Graham Denis
Publisher: name: London South Bank University
Year: 1979

description: A literature survey was carried out concerning the function and determination of Fluoride with respect to biological materials. As a result two methods of fluoride determination, the Fluoride Ion-selective Electrode (FISE) and a solvent extraction/GLC method were selected for detailed investigation. Studies using the FISE revealed that cationic species e.g. calcium and magnesium ions removed fluoride ions from solution, thus rendering them indeterminable, an effect partially reversible by the presence of carboxylic acids. Individual amino acids were shown not to be capable of removing fluoride ions from solution whilst milk proteins were so, their degree of success being dependent on the completeness of their three-dimensional structure. The possibility of two protein binding sites for fluoride ions is discussed. The solvent extraction/GLC method for the determination of fluoride was critically examined and shown to accurately and repeatably determine total fluoride, depending on the conditions used, in full—cream and skimmed milks up to concentrations of 100 μg ml-1. The use of cyclohexane as organic solvent has been examined and it has been shown to be equally efficient as benzene. No association between fluoride ions and milk proteins was determinable using Gel Filtration studies of fluoridated milk due to the mechanism of separation entailed. 19 F NMR studies of fluoride ions in solution confirmed the findings using the FISE with respect to the removal of fluoride ions from solution. The effects of pH and temperature on the resonance shifts observed relative to the proton shift of water were also investigated. Electro-Optic studies using milk proteins and fluoride ions showed that ‘primary micelles’ are capable of binding more fluoride than milk protein alone. The site of binding of fluoride ions was discussed in connection with the existence of two binding sites.
MOESM1 of Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan
Creators: name: Karah, Nabil
name: Fizza Khalid
name: Wai, Sun
name: Uhlin, Bernt
name: Ahmad, Irfan
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1: Figure S1. The geographic distance between the Combined Military Hospital in Lahore (CMH Lahore) and the Combined Military Hospital in Peshawar (CMH Peshawar) as drawn by Google Maps https://www.google.com/maps/dir/Combined+Military+Hospital,+Mall+Rd,+Peshawar+Cantonment,+Peshawar,+Khyber+Pakhtunkhwa,+Pakistan/CMH+Lahore,+Abdul+Rehman+Rd,+Saddar+Town,+Lahore,+Punjab,+Pakistan/@32.7700744,72.6522947,8z/data=!4m14!4m13!1m5!1m1!1s0x38d917bbe7a07855:0xf8ccf377d1a61673!2m2!1d71.5423502!2d34.0033769!1m5!1m1!1s0x39190517756f887b:0xc49fc1d23f55d0b0!2m2!1d74.3726762!2d31.5408931!3e0.
Additional file 1 of Clinical correlates of women endorsing premenstrual suicidal ideation: a cross-sectional study
Creators: name: Carlini, Sara V.
name: Weiss, Sandra J.
name: Mordukhaev, Lauren
name: Jacob, Sunu
name: Flynn, Heather A.
name: Deligiannidis, Kristina M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1.
An in vitro model for immune control of chlamydial growth in polarized epithelial cells.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: A polarized epithelial culture system and chlamydia-specific T-cell lines and clones were employed to investigate the ability and mechanisms by which T cells control the growth of chlamydiae in epithelial cells. Monolayers of polarized mouse epithelial cells were infected with the Chlamydia trachomatis agent of mouse pneumonitis (MoPn) and then exposed to antigen-stimulated MoPn-specific T-cell lines and clones. The results revealed that in vivo-protective MoPn-specific T-cell lines and clone 2.14-0 were capable of inhibiting the growth of MoPn in polarized epithelial cells. In contrast, the nonprotcctive MoPn-specific T-cell clone 2.14-3, naive splenic T cells, and a control T-cell clone could not inhibit the growth of MoPn in epithelial cells.
MOESM4 of Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan
Creators: name: Karah, Nabil
name: Fizza Khalid
name: Wai, Sun
name: Uhlin, Bernt
name: Ahmad, Irfan
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 4: File S1. CLUSTAL O(1.2.4) multiple sequence alignment of ampC-3 and ampC-8.
"example_code.py" of "Search for an anomalous excess of inclusive charged-current $\nu_e$ interactions in the MicroBooNE experiment using Wire-Cell reconstruction"
Creators: name: MicroBooNE Collaboration
Publisher: name: HEPData
Year: 2022

description: Example code for plotting unconstrained and constrained $\nu_e$CC FC
description: Data release for the first results from MicroBooNE's inclusive $\nu_e$CC search using Wire-Cell reconstruction, corresponding to information from arXiv:2110.13978. Attached is a python script which shows an example of how to use this data release to plot the unconstrained and constrained $\nu_e$CC FC data and predictions. Version 2 adds $\nu_\mu$CC energy resolution matrices, and fixes a small issue in the previous version in which the bins in the $\nu_e$CC energy resolution matrices were shifted by 50 MeV.
A technical report on hitting times, mixing and cutoff
Creators: name: Hermon, Jonathan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60J27

description: Consider a sequence of continuous-time irreducible reversible Markov chains and a sequence of initial distributions, $μ_n$. The sequence is said to exhibit $μ_n$-cutoff if the convergence to stationarity in total variation distance is abrupt, w.r.t. this sequence of initial distributions. In this work we give a characterization of $μ_n$-cutoff for an arbitrary sequence of initial distributions $μ_n$ (in the above setup). Our characterization is expressed in terms of hitting times of sets which are "worst" w.r.t. $μ_n$. Consider a Markov chain on $Ω$ whose stationary distribution in $π$. Let $t_{\mathrm{H}}(α) :=\max_{x \in Ω,A \subset Ω:\,π(A) \ge α}\mathbb{E}_{x}[T_{A}]$ be the expected hitting time of the worst set of size at least $α$. It was recently proved by Peres and Sousi and independently by Oliveira that $t_{\mathrm{H}}(1/4) $ captures the order of the mixing time. In this work we further refine this connection and show that $μ_n$-cutoff can be characterized in terms of concentration of hitting times (starting from $μ_n$) of sets which are worst in expectation w.r.t. $μ_n$. Conversely, we construct a counter-example which demonstrates that in general cutoff (as opposed to cutoff w.r.t. a certain sequence of initial distributions) cannot be characterized in this manner. Finally, we also prove that there exists an absolute constant $C$ such that for every Markov chain $ε( t_{\mathrm{H}}(ε)-t_{\mathrm{H}}(1-ε)) \le Ct_{\mathrm{rel}} |\log ε|$, for all $0< ε< 1/2$, where $t_{\mathrm{rel}} $ is the inverse of the spectral gap of the chain.
description: 21 pages, 2 figures. In the last version some typos were corrected
Characterization of the low-molecular-mass proteins of virulent Treponema pallidum.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: We previously demonstrated that Treponema pallidum cells incubated in vitro in the presence of heat-inactivated normal rabbit serum (HINRS) synthesize, in very small quantities, several pathogen-specific, low-molecular-mass proteins that appear to be localized extracellularly. In this study, we have taken advantage of our ability to metabolically radiolabel T. pallidum cells to high specific activity to further characterize these antigens. We found that the low-molecular-mass proteins are not related to the 15- and 17-kDa detergent-phase proteins (J. D. Radolf, N. R. Chamberlain, A. Clausell, and M. V. Norgard, Infect. Immun. 56:490-498, 1988). The low-molecular-mass proteins did not incorporate 3H-labeled fatty acids and were not precipitated by rabbit immunoglobulin G (IgG) antibodies directed against glutathione S-transferase fusions to the nonlipidated 15- and 17-kDa proteins. We prepared polyclonal antisera to the low-molecular-mass proteins by immunizing two rabbits with the concentrated supernatant of T. pallidum cells. IgG antibodies present in the sera of both rabbits precipitated a 21.5-kDa protein from solubilized extracts of T. pallidum supernatant and cells. IgG antibodies in the serum of the second rabbit precipitated an additional 15.5-kDa low-molecular-mass protein only from solubilized extracts of supernatant. While investigating the effect of eliminating HINRS from the extraction medium, we observed that the low-molecular-mass proteins remained associated with treponemal cells that were incubated in the absence of HINRS. These proteins could be eluted from the cells by the addition of HINRS or rabbit serum albumin, suggesting that they are located on or near the treponemal cell surface. The 15.5- and 21.5-kDa low-molecular-mass proteins were not washed off treponemal cells with buffer containing 1 M KCl. Experiments employing selective solubilization of the T. pallidum outer membrane with 0.1% Triton X-114 and proteinase K accessibility indicated that the 15.5-kDa protein, but not the 21.5-kDa protein, is cell surface exposed.
Stable presentation length of 3-manifold groups
Creators: name: Yoshida, Ken'ichi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Geometric Topology (math.GT)
subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 57M05, 57M27 (Primary) 57M10, 57M20 (Secondary)

description: We introduce the stable presentation length of a finitely presented group. The stable presentation length of the fundamental group of a 3-manifold can be considered as an analogue of the simplicial volume. We show that the stable presentation length have some additive properties like the simplicial volume, and the simplicial volume of a closed 3-manifold is bounded from above and below by constant multiples of the stable presentation length of its fundamental group.
description: 34 pages, 15 figures. v3: Lemma 6.3 added, the proof of Proposition 6.7 corrected, references added, v4: references added