cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Stenocolletes Schrottky
Creators: name: Lucia, Mariano
name: Alvarez, Leopoldo J.
name: Gonzalez, Victor H.
name: Abrahamovich, Alberto H.
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Andrenidae
Stenocolletes

description: Genus Stenocolletes Schrottky
Stenocolletes Schrottky 1909: 253. Type species: Stenocolletes pictus Schrottky, 1909. Plesiomorpha Brèthes 1913: 108; Genise, 1984: 203 [homonym of Plesiomorpha Warren 1898, Type species: Plesiomorpha albinervis Brèthes, 1913]
Calchaquila Genise 1984: 203 [nomen novum for Plesiomorpha Brèthes 1913. Type species: Plesiomorpha albinervis Brèthes, 1913] [new synonym]
description: Published as part of Lucia, Mariano, Alvarez, Leopoldo J., Gonzalez, Victor H. & Abrahamovich, Alberto H., 2013, The identity of the enigmatic genus Stenocolletes Schrottky (Hymenoptera: Tiphiidae), pp. 492-496 in Zootaxa 3652 (4) on page 493, DOI: 10.11646/zootaxa.3652.4.7, http://zenodo.org/record/223277
المعارضة السياسية في الدولة المعاصرة بين الواجبات والحقوق والوسائل (دراسة فقهية)
Creators: name: Farhat, Emine Mohammed
Publisher: name: Manara - Qatar Research Repository
Year: 2024
Subjects: classificationCode: 50
subject: Philosophy and religious studies

description: إن الصراع بين الحاكم والمحكوم، والاعتراض على أدائه السياسي يعد من أقدم الظواهر التي عرفتها البشرية، حيث كثرت النظريات السياسية والطروحات الفكرية التي عالجت هذه الظاهرة. وأما فيما يتعلق بالجانب الإسلامي، فالإسلام لا يرى في ذلك أي مشكلة، واعتبر المعارضة السياسية سنة من سنن الله في الاختلاف، فهي تدخل في مبدأ المدافعة يقول تعالى: ﴿وَلَوۡلَا دَفۡعُ ٱللَّهِ ٱلنَّاسَ بَعۡضَهُم بِبَعۡضٖ لَّفَسَدَتِ ٱلۡأَرۡضُ وَلَٰكِنَّ ٱللَّهَ ذُو فَضۡلٍ عَلَى ٱلۡعَٰلَمِينَ﴾ [البقرة: 251] ، فالمدافعة آلية مهمة تعصم الأمة من الفساد، بالإضافة إلى أن المعارضة السياسية تستند إلى عدد من الأدلة الشرعية من القرآن والسنة النبوية الشريفة الأخرى. إلا أن الشريعة الإسلامية وضعت لها مجموعة من القواعد والضوابط والتي يجب أن تلتزم بها حتى تحقق المعارضة السياسية مقاصدها وهو جلب المنفعة ودرء المفسدة عن المجتمع. و تكمن الإشكالية في أن هناك من يرى بأن المعارضة السياسية هي بغي وخروج على السلطة السياسية. بينما هي ظاهرة طبيعية وصحية وإيجابية تصب في صالح المجتمع، فلا توجد دولة تخلو من المعارضة . ومن أجل دراسة هذا الموضوع قسمت الدراسة إلى مدخل وأربعة فصول، ويتبعها أهم النتائج والتوصيات.وجعلت المدخل في تعريف مفردات عنوان الرسالة،وبيان مصطلح المعارضة السياسية والفرق بينها وبين البغي.ووفي الفصل الأول ذكرت أهمية المعارضة السياسية والدور الذي تقوم به، والأدلة الشرعية التي تستند إلىيها في مشروعية المعارضة، ومقاصد الشريعة في المعارضة السياسية، بالإضافة إلى الضوابط والمبادئ الملزمة للمعارضة.وفي الفصل الثاني ذكرت مجموعة من الواجبات التي يجب أن تلتزم بها المعارضة السياسية، وهي الحفاظ على وحدة الأمة، والالتزام بالمرجعية الإسلامية، والالتزام بطاعة السلطة الشرعية، والقيام بواجب النصح للحاكم والمحكوم.وأما في الفصل الثالث فتناولت فيه حقوق المعارضة السياسية، وهي حق التعبير عن الآراء، وحق التدوال على السلطة، وحق مراقبة الحكام، وحق عزل الحاكم غير الشرعي.وفي الفصل الرابع عرضت بعض الوسائل لممارسة المعارضة السياسية، كإنشاء الأحزاب السياسية، والقيام بالاحتجاجات والمظاهرات السلمية، وإصدار الصحف ووسائل الإعلام، وكذلك الاستجوابات البرلمانية.وختمتُ البحث بذكر أهم النتائج و عدد من التوصيات.
Gymnuridae
Creators: name: Straube, Nicolas
name: White, William T.
name: Ho, Hsuan-Ching
name: Rochel, Elisabeth
name: Corrigan, Shannon
name: Li, Chenhong
name: Naylor, Gavin J. P.
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Elasmobranchii
Myliobatiformes
Gymnuridae

description: Family Gymnuridae
description: Published as part of Straube, Nicolas, White, William T., Ho, Hsuan-Ching, Rochel, Elisabeth, Corrigan, Shannon, Li, Chenhong & Naylor, Gavin J. P., 2013, A DNA sequence-based identification checklist for Taiwanese chondrichthyans, pp. 256-278 in Zootaxa 3752 (1) on page 275, DOI: 10.11646/zootaxa.3752.1.16, http://zenodo.org/record/285357
XDR of ultradispersed diamonds
Creators: name: Tytarenko, Valentina
name: Zabludovsky, Vladimir
name: Tytarenko, Igor
Publisher: name: Zenodo
Year: 2024

description: XDR of ultradispersed diamonds with nickel ions in paper 

Tytarenko V.V., Zabludovsky V.A., Tytarenko I.V. Laser-assisted electrodeposition of composite carbon-containing nickel coatings // Nanosistemi, Nanomateriali, Nanotehnologii, 2024, 22(1), pp. 41-52. https://doi.org/10.15407/nnn.22.01.041
Netzdienlicher Einsatz dezentraler Batterien im Verteilnetz
Creators: name: Schori, Stefan
name: Wienands, Steffen
name: Buntschu, Ron Bruno
name: Höckel, Michael
Year: 2022

description: Die Anzahl an PV-Anlagen mit Batterie­speicher nimmt stetig zu. Die dezentralen Batterie­speicher werden oft zur Maximierung des Eigen­verbrauchs eingesetzt. Mit modernen Betriebs­strategien könnten sie aber auch zur Netzstabilität beitragen. Über Simula­tionen wurde untersucht, wie das Verteilnetz durch netzdien­lichere Betriebs­strategien entlastet werden könnte.
INFORMATION TECHNOLOGIES IN LOGISTIC SYSTEMS
Creators: name: Yusupov, Axmadbek
name: Shokirov, Aziz
Publisher: name: Zenodo
Year: 2024

description: The application of Information Technologies (IT) in logistic systems has significantly transformed the management and optimization of logistics processes, including transportation, distribution, storage, and inventory management. This paper explores the key information technologies reshaping the logistics industry, focusing on their role in improving efficiency, customer satisfaction, and competitiveness, as well as their potential for future advancements in logistics operations.
Additional file 1: of Responding to the health needs of survivors of human trafficking: a systematic review
Creators: name: Hemmings, Stacey
name: Jakobowitz, Sharon
name: Abas, Melanie
name: Bick, Debra
name: Howard, Louise
name: Stanley, Nicky
name: Zimmerman, Cathy
name: Oram, Sian
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: PRISMA Checklist. (DOCX 19 kb)
A targeted fluorescent nanosensor for ratiometric pH sensing at the cell surface
Creators: name: Kromer, Charlotte
name: Katz, Aaron
name: Feldmann, Ines
name: Laux, Peter
name: Luch, Andreas
name: Tschiche, Harald R.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: pH sensor
subject: pH
subject: pHe
subject: Nanosensor
subject: Extracellular pH
subject: Targeting
subject: Nanoparticles
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: The correlation between altered extracellular pH and various pathological conditions, including cancer, inflammation and metabolic disorders, is well known. Bulk pH measurements cannot report the extracellular pH value at the cell surface. However, there is a limited number of suitable tools for measuring the extracellular pH of cells with high spatial resolution, and none of them are commonly used in laboratories around the world. In this study, a versatile ratiometric nanosensor for the measurement of extracellular pH was developed. The nanosensor consists of biocompatible polystyrene nanoparticles loaded with the pH-inert reference dye Nile red and is surface functionalized with a pH-responsive fluorescein dye. Equipped with a targeting moiety, the nanosensor can adhere to cell membranes, allowing direct measurement of extracellular pH at the cell surface. The nanosensor exhibits a sensitive ratiometric pH response within the range of 5.5–9.0, with a calculated pKa of 7.47. This range optimally covers the extracellular pH (pHe) of most healthy cells and cells in which the pHe is abnormal, such as cancer cells. In combination with the nanosensors ability to target cell membranes, its high robustness, reversibility and its biocompatibility, the pHe nanosensor proves to be well suited for in-situ measurement of extracellular pH, even over extended time periods. This pH nanosensor has the potential to advance biomedical research by improving our understanding of cellular microenvironments, where extracellular pH plays an important role.
Preparing students to deal with the consequences of the workforce shortage among health professionals: a qualitative approach
Creators: name: Golz, Christoph
name: Oulevey Bachmann, Annie
name: Defilippis, Tiziana Sala
name: Kobleder, Andrea
name: Peter, Karin
name: Schaffert, René
name: Schwarzenbach, Xenia
name: Kampel, Thomas
name: Hahn, Sabine
Publisher: name: BioMed Central
Year: 2022

description: Background Healthcare is facing a shortage of qualified healthcare professionals. The pandemic has brought to light the fragile balance that affects all healthcare systems. Governments have realized that these systems and the professionals working in them need support at different levels to strengthen the retention of the workforce. Health professionals’ education can play an important role in ensuring that new generations of workers have sound personal and professional competencies to successfully face the challenges of professional practice. These challenges are described in the literature, but the extent to which they are considered in health professionals’ education is less clear. Methods This qualitative study compares the professional challenges and educational needs described in the literature with the current curricula for health professionals offered in Switzerland. Data were collected nationally through focus group interviews with 65% of Switzerland’s directors of bachelor’s and master’s programs of health professions (nursing, physiotherapy, occupational therapy, midwifery, nutrition and dietetics, osteopathy, radiologic medical imaging technology, health promotion and prevention, and health sciences). The data attained were analyzed using knowledge mapping. Results The results reveal a gap among education programs with regard to occupational health promotion and cultural diversity. Both topics are taught with a sole focus on patients, and students are expected to adopt similar strategies for their health promotion and stress management. Physicians are insufficiently involved in interprofessional education. The programs fail to enhance health professionals’ political, economic and digital competencies. Conclusion The results of this study offer clear guidance about what topics need to be integrated into curricula to improve health professionals’ well-being at work and their preparedness to face daily professional challenges.
Insigniocastnia J. Y. Miller. The 2007
Creators: name: Worthy, Robert
name: González, Jorge M.
name: Ríos, Sergio D.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Castniidae
Insigniocastnia

description: Review of Insigniocastnia J. Y. Miller, 2007
Synonymic list
Insigniocastnia J. Y. Miller, 2007 (type species: Insigniocastnia taisae J. Y. Miller, 2007) bogota (Strand, 1912) comb. nov.
bogota—Castnia bogota Strand, 1912 bogata—Athis bogata J. Y. Miller, 1995 (ISS) taisae—Insigniocastnia taisae J. Y. Miller, 2007 (JSS) syn. nov.
ISS Incorrect subsequent spelling
JH Junior homonym
JSS Junior subjective synonym
description: Published as part of Worthy, Robert, González, Jorge M. & Ríos, Sergio D., 2019, A review of the genus Insigniocastnia J. Y. Miller, 2007 (Lepidoptera: Castniidae) with notes on Castnia amalthaea H. Druce, 1890, pp. 277-288 in Zootaxa 4550 (2) on pages 281-282, DOI: 10.11646/zootaxa.4550.2.8, http://zenodo.org/record/2625369
Praxistagung: Gemeinsam für eine gute Ausbildung angehender Fachpersonen
Creators: name: Friedli, Fabienne
name: Marti, Barbara
name: Pulver, Caroline
Publisher: name: Berner Fachhochschule BFH, Soziale Arbeit
Year: 2022

description: Die Tagung Praxisausbildung im Frühling 2022 stand im Zeichen des neuen Bachelors in Sozialer Arbeit. Im Herbst 2023 soll das neue Curriculum starten. Das Umsetzungsprojekt hat unterdessen verschiedene Meilensteine erreicht und ist auf Kurs. Auch für die Zusammenarbeit mit der Praxis sind Neuerungen vorgesehen.
Continuous protein-density gradients: A new approach to correlate physical cues with cell response
Creators: name: Zhang, Shanshan
name: Felthaus, Oliver
name: Prantl, Lukas
name: Ma, Nan
name: Machatschek, Rainhard
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: laminin
subject: gradient
subject: Langmuir–Blodgett
subject: hADSC
subject: single-cell force spectroscopy
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: To assess cellular behavior within heterogeneous tissues, such as bone, skin, and nerves, scaffolds with biophysical gradients are required to adequately replicate the in vivo interaction between cells and their native microenvironment. In this study, we introduce a strategy for depositing ultrathin films comprised of laminin-111 with precisely controlled biophysical gradients onto planar substrates using the Langmuir–Blodgett (LB) technique. The gradient is created by controlled desynchronization of the barrier compression and substrate withdrawal speed during the LB deposition process. Characterization of the films was performed using techniques such as atomic force microscopy and confocal fluorescence microscopy, enabling the comprehensive analysis of biophysical parameters along the gradient direction. Furthermore, human adipose-derived stem cells were seeded onto the gradient films to investigate the influence of protein density on cell attachment, showing that the distribution of the cells can be modulated by the arrangement of the laminin at the air–water interface. The presented approach not only allowed us to gain insights into the intricate interplay between biophysical cues and cell behavior within complex tissue environments, but it is also suited as a screening approach to determine optimal protein concentrations to achieve a target cellular output.
Additional file 5: of A novel lipid transfer protein from the pea Pisum sativum: isolation, recombinant expression, solution structure, antifungal activity, lipid binding, and allergenic properties
Creators: name: Bogdanov, Ivan
name: Zakhar Shenkarev
name: Finkina, Ekaterina
name: Melnikova, Daria
name: Rumynskiy, Eugene
name: Arseniev, Alexander
name: Ovchinnikova, Tatiana
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Comparison of the measured and calculated molecular masses of tryptic fragments of the reduced Ps-LTP1. (DOCX 19 kb)
The Noble Qur’an in the Prophet’s Era
Creators: name: Adi, Fatima Mokhles
Publisher: name: Manara - Qatar Research Repository
Year: 2024
Subjects: classificationCode: 50
subject: Philosophy and religious studies

description: This research is concerned with a historical issue, which is gathering, memorizing, blogging and arranging of holy Quran. In order to reach these facts, it is necessary to collect the facts from Sunnah's books, by which we can learn about the aspects of the Quran during prophet Mohamed presence, then consider the acceptable facts from it and exclude the lies. We also use the words of Muslim scholars who have studied this subject and spoken about it in their literature, and we conclude in the end that The Qur’an was surrounded by the highest levels of memorization and care since the first era, So the entire Qur’an was memorized by a large number of the Prophet’s companions, The Prophet used to order his companions to write down everything that was revealed from the Noble Qur’an, and he guides them to the places of the verses in the surah, We conclude at the end of the first topic that the Holy Qur’an was completely transcribed at the time of the Prophet’s death, but in separate places, And there were a large number of companions memorizing the entire Qur’an. The research then moves on to a second stage, which is to gather what has been said about the Quran in the Prophetic Era among Western scholars, to mention their words, to discuss them and to discuss their methods in a scientific way, and to prove that they disagree very much with the Islamic vision, as they do not use the method of Muslims in accepting the Islamic facts, in our discussion of them, it becomes clear exactly where the dispute is, It also shows the weakness that characterizes their opinions and approaches.
Datenerhebung zur Häufigkeit von Sturz und Dekubitus. Eine Hilfe auf dem weg zur Qualitätsentwicklung und Professionalisierung in der Langzeitpflege?
Creators: name: Vangelooven, Christa
name: Hahn, Sabine
Publisher: name: Hogrefe
Year: 2013

description: Der Artikel präsentiert die wichtigsten Ergebnisse einer im Jahr 2011 durchgeführten nationalen Prävalenzmessung zu Sturz und Dekubitus in den Akutspitälern der Schweiz, bei der auch einige Langzeitinstitutionen auf freiwilliger Basis teilgenommen haben. Welchen Nutzen haben die Ergebnisse für Qualitätsentwicklung und Professionalisierung in der Langzeitpflege?
Carex melanostachya Willd.
Creators: name: Info Flora
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Cyperaceae
Carex
Carex melanostachya

description: Carex melanostachya Willd.
Art ISFS: 90000 Checklist: 1010010 Cyperaceae Carex Carex melanostachya Willd.
Bestimmungsschlüssel
ZusammenfassungKEINE ANGABE
Ökologie
Lebensraum Lebensraumnach Delarze & al. 2015
KEINE ANGABE
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl F--Lichtzahl L--Salzzeichen--Reaktionszahl R--Temperaturzahl T--Nährstoffzahl N--Kontinentalitätszahl K--
Nomenklatur
Gültiger Name (Checklist 2017):Carex melanostachyaWilld.
Volksname
Deutscher Name: -- Nom français: -- Nome italiano: --
Übereinstimmung mit anderen Referenzwerken
RelationNomReferenzwerkeNo=Carex melanostachya Willd.Index synonymique 199690000=Carex melanostachya Willd.SISF/ISFS 290000
= Taxon stimmt mit akzeptiertem Taxon überein (Checklist 2017)  Taxon enthält (neben anderen) auch das akzeptierte Taxon (Checklist 2017)
Status Indigenat: -
Liste der gefährdeten Pflanzen IUCN(nach Walter & Gillett 1997): Nein
description: Published as part of Info Flora, 2021,
Gewalterzählungen: Was die Forschung von der Kunst lernen kann
Creators: name: Abraham, Andrea
Publisher: name: Berner Fachhochschule, Soziale Arbeit
Year: 2023

description: Die Autofiktion im «Blutbuch» von Kim de l’Horizon greift viele Fragen auf, die BFH-Dozentin Andrea Abraham in ihren Forschungen beschäftigen. Dies stellte sie eher zufällig fest, als sie das Buch zur Hand nahm. Tauchen auch Sie in ihr sehr persönliches Leseerlebnis ein.
Rural Household's Income Diversification, Climate Risk and Wetland Ecosystem: Case Study in Tha Nat Pin Township, Bago Region, Myanmar
Creators: name: Soe, Thi Thi
name: Giuliani, Alessandra
name: Mon, Myat Yi
Year: 2020
Subjects: socioeconomics
livelihood activities
income diversification
Myanmar

description: An arm of the Andaman Sea in the southern part of Myanmar, Gulf of Mottama Region (GoM), is supporting both coastal population and agricultural productivity in Bago Region and Mon State. The livelihoods in the rural sector depend on agriculture, livestock, and fishing and self-employment activities. In the Gulf of Mottama Region, aquaculture is essential to work to create income generation for fisherman. The study investigates the socioeconomic situation and income diversification from different sources of group livelihood activities in Tha Nat Pin Township, Bago Region. Snowball sampling technique was adopted in the collection of 109 rural households using a semi-structured questionnaire and focus group discussion. Both descriptive and one-way ANOVA statistics were employed to verifythe objectives of the study. The result of the analysis showed that the majority of sampled households havea mean age of 45 years with an average family size of 5 people. The majority of sampled households completed primary school education (74%) and 41% of the income-earning member is from international migration. The study revealed that above 80% of flooding in these studied areas directly destroyed the farmlands, fish pondsand livestock and housing. The findings showed that agriculture is the highest income shared in these villages where 66% of sampled farmers grew in monsoon and summer seasons. The study found that the highest annual mean income earned from three types of livelihood groups included agriculture, fishery and livestock (US$32,085) in Tha Nat Tan Village (TNT). In Aung Bone Gyi Village, four types of livelihood groups (agriculture, fishery, livestock and small business) earned US$22,427 and only one livelihood group as agricultural crop production (US$5,504) inKywe Hphyu Chaung Village (KPC). The better-off group was found in Tha Nat Tan Village(above 78%), in Aung Bone Gyi Village and Kywe Hphyu Chaung Village(nearly 60%). One-third of sampled respondents receivedpoor income return fromlivelihood with less diversification groups. More diversified livelihood options obtainedhigher income than only one livelihood option. Agriculture plus other livelihood activities can earn better-off level of sampled household inthis study. It was recommended that agricultural crop production should be adequately improvedwith climate-smart agriculture technology and credit access and easy access toinput and farm machineries and post-harvest technology in these areas.
Carex michelii Host
Creators: name: Info Flora
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Cyperaceae
Carex
Carex michelii

description: Carex michelii Host
Art ISFS: 90100 Checklist: 1010020 Cyperaceae Carex Carex michelii Host
Bestimmungsschlüssel
ZusammenfassungKEINE ANGABE
Ökologie
Lebensraum Lebensraumnach Delarze & al. 2015
KEINE ANGABE
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl F--Lichtzahl L--Salzzeichen--Reaktionszahl R--Temperaturzahl T--Nährstoffzahl N--Kontinentalitätszahl K--
Nomenklatur
Gültiger Name (Checklist 2017):Carex micheliiHost
Volksname
Deutscher Name: -- Nom français: -- Nome italiano: --
Übereinstimmung mit anderen Referenzwerken
RelationNomReferenzwerkeNo=Carex michelii HostChecklist 201790100=Carex michelii HostIndex synonymique 199690100=Carex michelii HostLandolt 1977550=Carex michelii HostSISF/ISFS 290100
= Taxon stimmt mit akzeptiertem Taxon überein (Checklist 2017)  Taxon enthält (neben anderen) auch das akzeptierte Taxon (Checklist 2017)
Status Indigenat: -
Liste der gefährdeten Pflanzen IUCN(nach Walter & Gillett 1997): Nein
description: Published as part of Info Flora, 2021,
Digitale Transformation gemeinsam mit der Branche fördern
Creators: name: Winterberg, Norbert
Publisher: name: Berner Fachhochschule BFH, Architektur, Holz und Bau/Technik und Informatik
Year: 2023

description: Das Projekt «Plattform Wald & Holz 4.0» der BFH wird ein Forum für die Förderung der digitalen Transformation in Unternehmen der Wald- und Holzwirtschaft. Unterstützung erfolgt auf zwei Ebenen: zum einen durch die Entwicklung eines branchenspezifischen Strategieprozesses für einen systematischen Umgang mit der Digitalisierung, zum anderen durch die Entwicklung von Lösungsansätzen für wesentliche Transformationshindernisse in der Branche. Erarbeitet werden die Inhalte mit Partnerunternehmen.
Intake of Processed Meat and Association with Sociodemographic and Lifestyle Factors in a Representative Sample of the Swiss Population
Creators: name: Sych, Janice
name: Kälin, Ivo
name: Gerlach, Fabienne
name: Wróbel, Anna
name: Le, Thu
name: FitzGerald, Rex
name: Pestoni, Giulia
name: Fäh, David
name: Krieger, Jean-Philippe
name: Rohrmann, Sabine
Publisher: name: Molecular Diversity Preservation International
Year: 2019

description: Processed meat (PM) intake is associated with health risks, but data are lacking in Switzerland. Using national representative data from a recent menuCH Survey, we first aimed to quantify intake of PM and its subtypes, and second to investigate associations with sociodemographic and lifestyle factors by multivariable regression analysis. PM was consumed by 72% of the population, and mean daily intake was 42.7 g/day (standard error of the mean (SEM) 1.2 g/day), ranging considerably across PM subtypes: highest intake of sausages 18.1 g/day (SEM 0.7 g/day) and lowest of bacon 2.0 g/day (SEM 0.2 g/day). PM intake by women was 4.7 g/1000 kcal lower than men (95% confidence interval (CI):
Characterisation of ten NS2B-NS3 proteases: Paving the way for pan-flavivirus drugs
Creators: name: Voss, Saan
name: Rademann, Jörg
name: Nitsche, Christoph
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Flavivirus
subject: NS2B-NS3
subject: Antivirals
subject: Protease inhibitors
subject: Broad-spectrum
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::615 Pharmakologie, Therapeutik

description: Flaviviruses can cause severe illness in humans. Effective and safe vaccines are available for some species; however, for many flaviviruses disease prevention or specific treatments remain unavailable. The viral replication cycle depends on the proteolytic activity of the NS2B-NS3 protease, which releases functional viral proteins from a non-functional polyprotein precursor, rendering the protease a promising drug target. In this study, we characterised recombinant NS2B-NS3 proteases from ten flaviviruses including three unreported proteases from the Usutu, Kyasanur forest disease and Powassan viruses. All protease constructs comprise a covalent Gly4-Ser-Gly4 linker connecting the NS3 serine protease domain with its cofactor NS2B. We conducted a comprehensive cleavage site analysis revealing areas of high conversion. While all proteases were active in enzymatic assays, we noted a 1000-fold difference in catalytic efficiency across proteases from different flaviviruses. Two bicyclic peptide inhibitors displayed anti-pan-flaviviral protease activity with inhibition constants ranging from 10 to 1000 nM.
MOESM2 of Detection of tumor-associated cells in cryopreserved peripheral blood mononuclear cell samples for retrospective analysis
Creators: name: Peixuan Zhu
name: Stanton, Melissa
name: Castle, Erik
name: Joseph, Richard
name: Adams, Daniel
name: Shuhong Li
name: Platte Amstutz
name: Cha-Mei Tang
name: Ho, Thai
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Additional file 2: Table S1. Recovery efficiency of spiked HUVECs.
Additional file 4: of Responding to the health needs of survivors of human trafficking: a systematic review
Creators: name: Hemmings, Stacey
name: Jakobowitz, Sharon
name: Abas, Melanie
name: Bick, Debra
name: Howard, Louise
name: Stanley, Nicky
name: Zimmerman, Cathy
name: Oram, Sian
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Quality appraisal checklist. (DOCX 15 kb)
Perinatal mortality in German dairy cattle: Unveiling the importance of cow-level risk factors and their interactions using a multifaceted modelling approach
Creators: name: Zablotski, Yury
name: Voigt, Katja
name: Hoedemaker, Martina
name: Müller, Kerstin E.
name: Kellermann, Laura
name: Arndt, Heidi
name: Volkmann, Maria
name: Dachrodt, Linda
name: Stock, Annegret
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Cattle
subject: Medical risk factors
subject: Machine learning
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

description: Perinatal mortality (PM) is a common issue on dairy farms, leading to calf losses and increased farming costs. The current knowledge about PM in dairy cattle is, however, limited and previous studies lack comparability. The topic has also primarily been studied in Holstein-Friesian cows and closely related breeds, while other dairy breeds have been largely ignored. Different data collection techniques, definitions of PM, studied variables and statistical approaches further limit the comparability and interpretation of previous studies. This article aims to investigate the factors contributing to PM in two underexplored breeds, Simmental (SIM) and Brown Swiss (BS), while comparing them to German Holstein on German farms, and to employ various modelling techniques to enhance comparability to other studies, and to determine if different statistical methods yield consistent results. A total of 133,942 calving records from 131,657 cows on 721 German farms were analyzed. Amongst these, the proportion of PM (defined as stillbirth or death up to 48 hours of age) was 6.1%. Univariable and multivariable mixed-effects logistic regressions, random forest and multimodel inference via brute-force model selection approaches were used to evaluate risk factors on the individual animal level. Although the balanced random forest did not incorporate the random effect, it yielded results similar to those of the mixed-effect model. The brute-force approach surpassed the widely adopted backwards variable selection method and represented a combination of strengths: it accounted for the random effect similar to mixed-effects regression and generated a variable importance plot similar to random forest. The difficulty of calving, breed and parity of the cow were found to be the most important factors, followed by farm size and season. Additionally, four significant interactions amongst predictors were identified: breed—calving ease, breed—season, parity—season and calving ease—farm size. The combination of factors, such as secondiparous SIM breed on small farms and experiencing easy calving in summer, showed the lowest probability of PM. Conversely, primiparous GH cows on large farms with difficult calving in winter exhibited the highest probability of PM. In order to reduce PM, appropriate management of dystocia, optimal heifer management and a wider use of SIM in dairy production are possible ways forward. It is also important that future studies are conducted to identify farm-specific contributors to higher PM on large farms.
Autoantibodies from patients with kidney allograft vasculopathy stimulate a proinflammatory switch in endothelial cells and monocytes mediated via GPCR-directed PAR1-TNF-α signaling
Creators: name: Moll, Guido
name: Luecht, Christian
name: Adu Gyamfi, Michael
name: Da Fonseca, Dennyson L. M.
name: Wang, Pinchao
name: Zhao, Hongfan
name: Gong, Zexian
name: Chen, Lei
name: Ashraf, Muhamad Imtiaz
name: Heidecke, Harald
name: Hackel, Alexander Maximilian
name: Dragun, Duska
name: Budde, Klemens
name: Penack, Olaf
name: Riemekasten, Gabriela
name: Cabral-Marques, Otávio
name: Witowski, Janusz
name: Catar, Rusan
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: chronic kidney disease (CKD)
subject: end-stage renal disease (ESRD)
subject: kidney transplantation (KTx)
subject: kidney allograft vasculopathy
subject: endothelial cells (ECs)
subject: non-HLA-directed regulatory autoantibodies (RABs)
subject: autoantibodies
subject: tumor necrosis factor-alpha (TNF-alpha)
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Non-HLA-directed regulatory autoantibodies (RABs) are known to target G-protein coupled receptors (GPCRs) and thereby contribute to kidney transplant vasculopathy and failure. However, the detailed underlying signaling mechanisms in human microvascular endothelial cells (HMECs) and immune cells need to be clarified in more detail. In this study, we compared the immune stimulatory effects and concomitant intracellular and extracellular signaling mechanisms of immunoglobulin G (IgG)-fractions from kidney transplant patients with allograft vasculopathy (KTx-IgG), to that from patients without vasculopathy, or matched healthy controls (Con-IgG). We found that KTx-IgG from patients with vasculopathy, but not KTx-IgG from patients without vasculopathy or Con-IgG, elicits HMEC activation and subsequent upregulation and secretion of tumor necrosis factor alpha (TNF-alpha) from HMECs, which was amplified in the presence of the protease-activated thrombin receptor 1 (PAR1) activator thrombin, but could be omitted by selectively blocking the PAR1 receptor. The amount and activity of the TNF-alpha secreted by HMECs stimulated with KTx-IgG from patients with vasculopathy was sufficient to induce subsequent THP-1 monocytic cell activation. Furthermore, AP-1/c-FOS, was identified as crucial transcription factor complex controlling the KTx-IgG-induced endothelial TNF-alpha synthesis, and mircoRNA-let-7f-5p as a regulatory element in modulating the underlying signaling cascade. In conclusion, exposure of HMECs to KTx-IgG from patients with allograft vasculopathy, but not KTx-IgG from patients without vasculopathy or healthy Con-IgG, triggers signaling through the PAR1-AP-1/c-FOS-miRNA-let7-axis, to control TNF-alpha gene transcription and TNF-alpha-induced monocyte activation. These observations offer a greater mechanistic understanding of endothelial cells and subsequent immune cell activation in the clinical setting of transplant vasculopathy that can eventually lead to transplant failure, irrespective of alloantigen-directed responses.
Older adults’ suggestions of research topics on ageing well in urban environments – A participatory study
Creators: name: Oeser, Philip
name: Bruckmann, Nora
name: Gellert, Paul
name: Herrmann, Wolfram J.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: Aging
subject: Residence Characteristics
subject: Urbanization
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: BackgroundAgeing societies and urbanization are global phenomena that pose new challenges for care delivery. It is important to create a scientific evidence base to prepare for these changes. Hence, the aim of our study was to assess which research agenda older adults living in an urban environment in Germany suggest.MethodsA total of 1000 participants aged 65 years or older from five different neighborhoods of Berlin were randomly chosen and were sent a single item questionnaire allowing them to freely propose research topics regarding ageing well in the city. Codes were developed inductively and clustered into categories. In a second stage, these results were discussed with the participants and local stakeholders in a workshop and video calls.Results102 persons suggested 18 research topics in 6 categories: health, living environment, social issues, mobility, and accessibility to information and communication. Proposed research topics ranged from accessibility of health care, green spaces and recreational means to social involvement and loneliness.ConclusionThere is a substantial interest of older adults for research regarding their living situation. Research projects and local urban planning committees are encouraged to invite older adults to participate and integrate their perspectives suggested by older adults.
Racial discrimination within United Nations offices in Geneva: Results from an online survey
Creators: name: Strohmeier, Hannah
name: Musizvingoza, Ronald
name: Sajnani, Nisha
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2024
Subjects: subject: population groups
subject: racism
subject: ethnicity
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Racial discrimination adversely impacts health and well-being, and interferes with organizational functioning, including United Nations offices where limited systematic research exists. This article presents and discusses a secondary analysis of data from the 'Survey on Racial Discrimination' issued by the United Nations Staff Union Geneva in 2020. The survey produced quantitative and qualitative data and was completed by 1251 staff, consultants, and interns (response rate: 14.7%). Descriptive statistics were computed for key findings. More than one third (34.4%) of participants reported having personally experienced racial discrimination. Most reported national origin as basis (61.8%), stated that this experience had affected their opportunities for career advancement (66.2%), and took no action as response (57.4%), mainly due to a lack of trust in the organization's recourse mechanism. In addition, more than one third (34.3%) of survey participants had witnessed colleagues being racially discriminated against. Chi-square tests to assess differences between groups showed that those belonging to a racial, ethnic, and/or national minority or group reported higher rates of personally experienced and witnessed incidents of racial discrimination compared to those who did not identify as such. Furthermore, participants who reported having experienced racial discrimination had a higher proportion of witnessing racial discrimination. The qualitative survey data on suggested measures to address racial discrimination in the workplace were examined through thematic analysis and rendered three overarching themes: Understanding racial discrimination; revising practices of recruitment, promotion, and appointment; and restructuring case management processes. Our results suggest that racial discrimination poses a significant issue within United Nations offices in Geneva and call for educational initiatives and significant structural changes. We recommend tailored research to inform these measures and highlight that committed leadership and the participation and vigilance of all involved in shaping the culture of the organization is needed to address racial discrimination in the workplace.
Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis
Creators: name: Harnack, Christine
name: Berger, Hilmar
name: Liu, Lichao
name: Mollenkopf, Hans-Joachim
name: Strowig, Till
name: Sigal, Michael
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: Inflammtory bowel diseases
subject: colitis
subject: microbiota
subject: mucosal barrier
subject: colibactin
subject: E. coli
subject: stem cells
subject: regeneration
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Colibactin, a bacterial genotoxin produced by E. coli strains harboring the pks genomic island, induces cytopathic effects, such as DNA breaks, cell cycle arrest, and apoptosis. Patients with inflammatory bowel diseases, such as ulcerative colitis, display changes in their microbiota with the expansion of E. coli. Whether and how colibactin affects the integrity of the colonic mucosa and whether pks+ E. coli contributes to the pathogenesis of colitis is not clear. Using a gnotobiotic mouse model, we show that under homeostatic conditions, pks+ E. coli do not directly interact with the epithelium or affect colonic integrity. However, upon short-term chemical disruption of mucosal integrity, pks+ E. coli gain direct access to the epithelium, causing epithelial injury and chronic colitis, while mice colonized with an isogenic & UDelta;clbR mutant incapable of producing colibactin show a rapid recovery. pks+ E. coli colonized mice are unable to reestablish a functional barrier. In turn, pks+ E. coli remains in direct contact with the epithelium, perpetuating the process and triggering chronic mucosal inflammation that morphologically and transcriptionally resembles human ulcerative colitis. This state is characterized by impaired epithelial differentiation and high proliferative activity, which is associated with high levels of stromal R-spondin 3. Genetic overexpression of R-spondin 3 in colon myofibroblasts is sufficient to mimic barrier disruption and expansion of E. coli. Together, our data reveal that pks+ E. coli are pathobionts that promote severe injury and initiate a proinflammatory trajectory upon contact with the colonic epithelium, resulting in a chronic impairment of tissue integrity.
Measurement of patient awareness of the critical role played by clinical pharmacists in Saudi Arabia's healthcare
Creators: name: Anas Ali Alhur
name: Rana Alshahrani
name: Abdulrahman Almuntashiri
name: Safiah Asiri
name: Nouf Alotaibi
name: Shahad Althabtah
name: Ebtesam Almansour
name: Sara Assiri
name: Razan Alharbi
name: Laila Alameer
name: Rawabi Alamer
name: Seba Ali
name: Safiah Saad
name: Ziyad Asiri
Publisher: name: Zenodo
Year: 2025
Subjects: Clinical pharmacists, Patient awareness, Medication management, Public health, Saudi Arabia, Healthcare education, Trust, Cross-sectional study, Pharmacy services, Patient engagement

description: Background: Clinical pharmacists play a crucial role in healthcare by ensuring safe and effective medication management, improving adherence, minimizing drug-related errors, and providing patient education. Despite their importance, public awareness of clinical pharmacists' contributions in Saudi Arabia remains limited. This study assesses patient awareness of clinical pharmacists’ roles, identifies factors influencing awareness, and provides recommendations for improvement.Methods: A quantitative, cross-sectional study was conducted using a structured online questionnaire distributed to 936 participants across Saudi Arabia. The questionnaire covered demographics, knowledge, awareness, trust, and willingness to learn about clinical pharmacists. Data were analyzed using SPSS v26.0, employing descriptive and inferential statistics, including chi-square tests and logistic regression.Results: The majority of participants (88.4%) were aware of clinical pharmacists, with higher awareness among females (93%) than males (82.5%). Awareness varied significantly by age and education level (p<0.01). Trust in clinical pharmacists’ advice increased with higher education levels. Most participants expressed willingness to learn more about clinical pharmacists, particularly those with chronic health conditions. Logistic regression identified gender and education as significant predictors of awareness, while trust was the strongest predictor of willingness to learn.Conclusion: Although awareness of clinical pharmacists in Saudi Arabia is relatively high, knowledge gaps regarding their specific roles persist. Educational campaigns emphasizing role clarity, trust-building, and pharmacist-led public health initiatives are recommended to enhance public engagement and optimize healthcare outcomes. Future research should explore the long-term effects of targeted educational interventions on patient perceptions and behaviors.
Additional file 1: Table S1. of Evolutionary patchwork of an insecticidal toxin shared between plant-associated pseudomonads and the insect pathogens Photorhabdus and Xenorhabdus
Creators: name: Ruffner, Beat
name: Péchy-Tarr, Maria
name: Höfte, Monica
name: Bloemberg, Guido
name: Grunder, Jürg
name: Keel, Christoph
name: Maurhofer, Monika
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Bacterial strains used in this study [60–106].
Additional file 1: of Next of kinâ  s experiences of involvement during involuntary hospitalisation and coercion
Creators: name: FĂ¸Rde, Reidun
name: Norvoll, Reidun
name: Hem, Marit
name: Pedersen, Reidar
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Interview guide to next of kin of adult patients. (DOCX 23Â kb)
Additional file 1: of Psychometric properties of the newly developed Physician Teaching Self-Efficacy Questionnaire (PTSQ)
Creators: name: Dybowski, Christoph
name: Kriston, Levente
name: Harendza, Sigrid
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: PTSQ Questionnaire. (DOCX 19Â kb)
Additional file 3: Figure S1. of Evolutionary patchwork of an insecticidal toxin shared between plant-associated pseudomonads and the insect pathogens Photorhabdus and Xenorhabdus
Creators: name: Ruffner, Beat
name: PĂŠchy-Tarr, Maria
name: HĂśfte, Monica
name: Bloemberg, Guido
name: JĂźrg Grunder
name: Keel, Christoph
name: Maurhofer, Monika
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Insecticidal activity correlates with presence of the fitD gene.
Latrunculia Du Bocage 1869
Creators: name: Mothes, Beatriz
name: Campos, Maurício
name: Eckert, Rafael
name: Lerner, Cléa
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Porifera
Demospongiae
Poecilosclerida
Latrunculiidae
Latrunculia

description: Genus Latrunculia Du Bocage, 1869
Definition. Latrunculiidae with polygonal large-meshed reticulation formed by wispy tracts of anisostyles. Megascleres are typically smooth and sinuous, occasionally polytylote anisostyles to which terminally spined styles or diactinal spicules may be added. Microscleres are anisodiscorhabds. Aciculoanisodiscorhabds, amphiaster-like microscleres, and acanthomicroxeas are present in one or other of two species. Microscleres are disposed in a palisade in the outer ectosome (Samaai & Kelly, 2002).
description: Published as part of Mothes, Beatriz, Campos, Maurício, Eckert, Rafael & Lerner, Cléa, 2008, Latrunculia (Latrunculia) tetraverticillata sp. nov. (Porifera, Poecilosclerida, Latrunculiidae) from the bathyal region off the coast of Santa Catarina State, Brazil, Southwestern Atlantic, pp. 59-65 in Zootaxa 1744 on page 61, DOI: 10.5281/zenodo.181621
Latrunculia Du Bocage 1869
Creators: name: Mothes, Beatriz
name: Campos, Maurício
name: Eckert, Rafael
name: Lerner, Cléa
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Porifera
Demospongiae
Poecilosclerida
Latrunculiidae
Latrunculia

description: Subgenus Latrunculia Du Bocage, 1869
Definition. Latrunculia species in which the anisodiscorhabd microscleres have three whorls of spines around the shaft, a basal whorl above the manubrium, and two whorls of projections, the median and subsidiary whorls, located closer to the apical whorl than to the manubrium (hence the use of the prefix aniso- in anisodiscorhabd). The basal whorl is clearly separated from the manubrium in most species but armours the manubrium in others, making the distinction from the manubrium more difficult (Samaai et al., 2006).
description: Published as part of Mothes, Beatriz, Campos, Maurício, Eckert, Rafael & Lerner, Cléa, 2008, Latrunculia (Latrunculia) tetraverticillata sp. nov. (Porifera, Poecilosclerida, Latrunculiidae) from the bathyal region off the coast of Santa Catarina State, Brazil, Southwestern Atlantic, pp. 59-65 in Zootaxa 1744 on page 61, DOI: 10.5281/zenodo.181621