cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
XYZ: four-quark states?
Creators: name: Pilloni, A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The observation of many unexpected states decaying into heavy quarkonia has challenged the usual Q-Qbar interpretation. We will discuss the nature of some of the charmonium-like resonances recently observed by BES III and LHCb, and their identication according to the compact tetraquark model. We also commment the production of light nuclei in hadron collisions and the relevance for the physics of the X(3872).
description: 5 pages, 2 figures, 1 table. Contribution to the proceedings of "IFAE 2015 Incontri di Fisica delle Alte Energie", Roma 8-10 April 2015
The impact of galactic outflows on the baryon cycle of local dwarf galaxies
Creators: name: Romano, Michael
Publisher: name: Zenodo
Year: 2023

description: Galactic feedback plays a fundamental role in the framework of galaxy formation and evolution. Dwarf galaxies are particularly affected by such feedback that can produce strong winds able to transport significant amount of gas, metals and dust into the circumgalactic (or even intergalactic) medium, drastically affecting their growth. We investigate the physical properties of galactic outflows in a sample of 29 local low-metallicity dwarf galaxies drawn from the Dwarf Galaxy Survey. We make use of Herschel/PACS archival data to detect atomic outflows in the broad wings of observed [CII] 158 \(\mu m\) line profiles. We find evidence of outflowing gas in 1/3 of the sample, and in the average galaxy population through line stacking. The outflow rates of our sources are comparable to their star-formation rates, implying mass-loading factors (i.e., outflow efficiencies) of the order of unity. Outflow velocities are larger than the velocities required from gas to escape away from the galaxies with, on average, ~40% of gas carried out into their intergalactic medium. Moreover, their energetics suggest that our outflows are consistent with momentum-driven winds powered by the radiation pressure of young stellar populations on dust grains, in agreement with observations of local starbursts.
 These results highlight the importance of feedback in the baryon cycle of low-mass sources. Indeed, galactic outflows powered by star formation are able to bring a significant amount of gas and dust out of the dark matter halos of dwarf galaxies, enriching their surroundings and shaping their star-formation histories. Our constraints on the mass-loading factors will be used as input for chemical evolution models attempting to reproduce the physical processes ruling the evolution of these galaxies across cosmic time.
A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors
Creators: name: Newby, Jay
name: Edelstein, Jasmine
name: Schiller, Jennifer L.
name: Lai, Samuel K.
name: Forest, M. Gregory
name: Wessler, Timothy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Biopolymeric matrices can impede transport of nanoparticulates and pathogens by entropic or direct adhesive interactions, or by harnessing "third-party" molecular anchors to crosslink nanoparticulates to matrix constituents. The trapping potency of anchors is dictated by association rates and affinities to both nanoparticulates and matrix; the popular dogma is that long-lived, high-affinity bonds to both species facilitate optimal trapping. Here we present a contrasting paradigm combining experimental evidence (using IgG antibodies and Matrigel®), a theoretical framework (based on multiple timescale analysis), and computational modeling. Anchors that bind and unbind rapidly from matrix accumulate on nanoparticulates much more quickly than anchors that form high-affinity, long-lived bonds with matrix, leading to markedly greater trapping potency of multiple invading species without saturating matrix trapping capacity. Our results provide a blueprint for engineering molecular anchors with finely tuned affinities to effectively enhance the barrier properties of biogels against diverse nanoparticulate species.Biological polymeric matrices often use molecular anchors, such as antibodies, to trap nanoparticulates. Here, the authors find that anchor-matrix bonds that are weak and short-lived confer superior trapping potency, contrary to the prevailing belief that effective molecular anchors should form strong bonds to both the matrix and the nanoparticulates.
Inflationary magnetogenesis, derivative couplings and relativistic Van der Waals interactions
Creators: name: Giovannini, Massimo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: When the gauge fields have derivative couplings to scalars, like in the case of the relativistic theory of Van der Waals (or Casimir-Polder) interactions, conformal invariance is broken but the magnetic and electric susceptibilities are not bound to coincide. We analyze the formation of large-scale magnetic fields in slow-roll inflation and find that they are generated at the level of a few hundredths of a nG and over typical length scales between few Mpc and $100$ Mpc. Using a new time parametrization that reduces to conformal time but only for coincident susceptibilities, the gauge action is quantized while the evolution equations of the corresponding mode functions are more easily solvable. The power spectra depend on the normalized rates of variation of the two susceptibilities (or of the corresponding gauge couplings) and on the absolute value of their ratio at the beginning of inflation. We pin down explicit regions in the parameter space where all the physical requirements (i.e. the backreaction constraints, the magnetogenesis bounds and the naturalness of the initial conditions of the scenario) are jointly satisfied. Weakly coupled initial data are favoured if the gauge couplings are of the same order at the end of inflation. Duality is systematically used to simplify the analysis of the wide parameter space of the model.
description: 40 pages, 12 included figures; minor corrected typos
A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance
Creators: name: Whitten, Andrew E.
name: Achard, Maud E.S.
name: Halili, Maria A.
name: Premkumar, Lakshmanane
name: Schembri, Mark A.
name: Martin, Jennifer L.
name: Kurth, Fabian
name: Totsika, Makrina
name: Heras, Begoña
name: Furlong, Emily J.
name: Lo, Alvin W.
name: Choudhury, Hassanul G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Copper resistance is a key virulence trait of the uropathogen Proteus mirabilis. Here we show that P. mirabilis ScsC (PmScsC) contributes to this defence mechanism by enabling swarming in the presence of copper. We also demonstrate that PmScsC is a thioredoxin-like disulfide isomerase but, unlike other characterized proteins in this family, it is trimeric. PmScsC trimerization and its active site cysteine are required for wild-type swarming activity in the presence of copper. Moreover, PmScsC exhibits unprecedented motion as a consequence of a shape-shifting motif linking the catalytic and trimerization domains. The linker accesses strand, loop and helical conformations enabling the sampling of an enormous folding landscape by the catalytic domains. Mutation of the shape-shifting motif abolishes disulfide isomerase activity, as does removal of the trimerization domain, showing that both features are essential to foldase function. More broadly, the shape-shifter peptide has the potential for ‘plug and play’ application in protein engineering.
Supplementary documentation for SAEON's field instrument data collected at the SIBHAYI BARO_CAMP station
Creators: name: South African Environmental Observation Network (SAEON) Grasslands-Forests-Wetlands Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Sibhayi
Hydrological
Barometer
Barometric pressure

description: This package contains supporting information for the hydrological data collected at SIBHAYI's BARO_CAMP station, as part of the South African Environmental Observation Network's monitoring projects.
Cyathea delgadii Pohl ex Sternb., Vers. Fl. Vorwelt
Creators: name: Lehnert, Marcus
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Cyatheales
Cyatheaceae
Cyathea
Cyathea delgadii

description: Cyathea delgadii Pohl ex Sternb., Vers. Fl. Vorwelt 1: 47. 1820.
 Range: — Costa Rica and Panama; Andes from Venezuela to Bolivia (BE, CO, LP, SC); eastern Paraguay, northeastern Argentina, and central to eastern Brazil
 Ecology: —Common in lower montane rainforests and gallery forests, preferring semi-shade but tolerating full sun, frequent on old landslides and along roads; 300–2000 m.
 Notes: —In northeastern Brazil, this species is used medicinally against shoulder dislocation, fever, and itchiness, and as a bath for allergies and dermatitis (Reinaldo et al. 2015).
 A variable species whose extremes can be mistaken for different species, here tentatively distinguished in the key. The typical form is found in perhumid premontane and montane forest of Costa Rica, the Andes and the mata atlântica of Brazil, mainly above 1000 m. The pubescent form occurs in premontane forest with weak seasonality and poor soils in the Venzuelan gran sabana, the Peruvian Huancabamba depression, and the Brazilian campo cerrado and only below 900 m. In Bolivia, it is found in Dept. Santa Cruz at the Andean knee, in the Serranía de Chiquitos and the Serranía de Huanchaca. We regard these forms as responses to the different climatic environments found at the respective elevations/vegetation zones. However, faintly distinct species have been included under C. delgadii, like Cyathea herzogii Rosenst. (see below) and Cyathea eggersii Hieron. (Lehnert et al., unpubl. data), and others may be separable in the future after more careful field studies.
description: Published as part of Lehnert, Marcus & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. XX. Cyatheaceae, pp. 118-134 in Phytotaxa 334 (2) on page 126, DOI: 10.11646/phytotaxa.334.2.2, http://zenodo.org/record/13721436
Cyathea dintelmannii Lehnert, Brittonia
Creators: name: Lehnert, Marcus
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Cyatheales
Cyatheaceae
Cyathea
Cyathea dintelmannii

description: Cyathea dintelmannii Lehnert, Brittonia 58: 237. 2006.
 Range: — Peru, Bolivia (CO, LP).
 Ecology: —Fairly common in perhumid montane rainforests, often on swampy ground in the understory; widespread but not very common; (1000–) 1300–2850 m.
 Notes: —Replaced in the northern Andes by the almost identical Cyathea guentheriana Lehnert (Lehnert 2009b).
description: Published as part of Lehnert, Marcus & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. XX. Cyatheaceae, pp. 118-134 in Phytotaxa 334 (2) on page 126, DOI: 10.11646/phytotaxa.334.2.2, http://zenodo.org/record/13721436
Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program
Creators: name: Wang, Ping
name: Cohen, Todd J.
name: Wander, Connor M.
name: Yuan, Chao-Xing
name: Bereman, Michael S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: TDP-43 pathology marks a spectrum of multisystem proteinopathies including amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and sporadic inclusion body myositis. Surprisingly, it has been challenging to recapitulate this pathology, highlighting an incomplete understanding of TDP-43 regulatory mechanisms. Here we provide evidence supporting TDP-43 acetylation as a trigger for disease pathology. Using cultured cells and mouse skeletal muscle, we show that TDP-43 acetylation-mimics promote TDP-43 phosphorylation and ubiquitination, perturb mitochondria, and initiate degenerative inflammatory responses that resemble sporadic inclusion body myositis pathology. Analysis of functionally linked amyotrophic lateral sclerosis proteins revealed recruitment of p62, ubiquilin-2, and optineurin to TDP-43 aggregates. We demonstrate that TDP-43 acetylation-mimic pathology is potently suppressed by an HSF1-dependent mechanism that disaggregates TDP-43. Our study illustrates bidirectional TDP-43 processing in which TDP-43 aggregation is targeted by a coordinated chaperone response. Thus, activation or restoration of refolding mechanisms may alleviate TDP-43 aggregation in tissues that are uniquely susceptible to TDP-43 proteinopathies.TDP-43 aggregation is linked to various diseases including amyotrophic lateral sclerosis. Here the authors show that acetylation of the protein triggers TDP-43 pathology in cultured cells and mouse skeletal muscle, which can be cleared through an HSF1-dependent chaperone mechanism that disaggregates the protein.
Airway surface liquid pH is not acidic in children with cystic fibrosis
Creators: name: Kreda, Silvia M.
name: Klimant, Ingo
name: Button, Brian
name: Montgomery, Samuel T.
name: Nguyen, Thien
name: Schultz, André
name: Kicic, Anthony
name: Puvvadi, Ramaa
name: Shaw, Nicole C.
name: Berry, Luke J.
name: Stick, Stephen M.
name: Borisov, Sergey M.
name: Noble, Peter B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Modulation of airway surface liquid (ASL) pH has been proposed as a therapy for cystic fibrosis (CF). However, evidence that ASL pH is reduced in CF is limited and conflicting. The technical challenges associated with measuring ASL pH in vivo have precluded accurate measurements in humans. In order to address this deficiency, ASL pH was measured in vivo in children using a novel luminescent technology integrated with fibre-optic probes. Here we show that ASL pH in children with CF is similar to that of children without CF. Findings were supported by highly controlled direct pH measurements in primary human airway epithelial cell culture models, which also suggest that the potential ASL pH gradient produced by defective apical ion transport is balanced out by paracellular shunting of acid/base. Thus, reduced baseline ASL pH is unlikely to be an important pathobiological factor in early CF lung disease.
Langeberg Central prescribed burning plan and line intercept, site 3320DD
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
Langeberg
prescribed burning

description: This is a scanned copy of a prescribed burning plan for Langeberg Central and a line intercept, including a diagram, of site 3320DD. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape. SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
Towards exotic hidden-charm pentaquarks in QCD
Creators: name: Chen, Hua-Xing
name: Chen, Wei
name: Liu, Xiang
name: Steele, T. G.
name: Zhu, Shi-Lin
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Lattice (hep-lat)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Inspired by $P_c(4380)$ and $P_c(4450)$ recently observed by LHCb, a QCD sum rule investigation is performed, by which they can be identified as exotic hidden-charm pentaquarks composed of an anti-charmed meson and a charmed baryon. Our results suggest that $P_c(4380)$ and $P_c(4450)$ have quantum numbers $J^P=3/2^-$ and $5/2^+$, respectively. Furthermore, two extra hidden-charm pentaqurks with configurations $\bar{D}Σ_c^*$ and $\bar{D}^*Σ_c^*$ are predicted, which have spin-parity quantum numbers $J^P=3/2^-$ and $J^P=5/2^+$, respectively. As an important extension, the mass predictions of hidden-bottom pentaquarks are also given. Searches for these partners of $P_c(4380)$ and $P_c(4450)$ are especially accessible at future experiments like LHCb and BelleII.
description: 5 pages and 1 figure. More discussions and references added. Accepted by Phys. Rev. Lett (in press)
Cyathea herzogii Rosenst., Meded. Rijks-Herb.
Creators: name: Lehnert, Marcus
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Cyatheales
Cyatheaceae
Cyathea
Cyathea herzogii

description: Cyathea herzogii Rosenst., Meded. Rijks-Herb. 19: 7. 1913.
 Range: — Peru, Bolivia (CO, LP).
 Ecology: —Common in upper mountain rain forests and elfin forests; 2000–3000 m.
 Notes: —Long confused with Cyathea delgadii but occurs at higher elevations and has overall duller scale and petiole colors (Lehnert 2009a). Commonly associated with C. austropallescens and C. carolihenrici.
description: Published as part of Lehnert, Marcus & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. XX. Cyatheaceae, pp. 118-134 in Phytotaxa 334 (2) on page 127, DOI: 10.11646/phytotaxa.334.2.2, http://zenodo.org/record/13721436
Combating subclonal evolution of resistant cancer phenotypes
Creators: name: Dalley, Brian K.
name: Quinlan, Aaron R.
name: Factor, Rachel E.
name: Layer, Ryan M.
name: Anderson, Layla A.
name: Jenkins, David F.
name: Qiao, Yi
name: Werner, Theresa L.
name: Shrestha, Gajendra
name: Pedersen, Brent S.
name: Gray, Joe W.
name: Marth, Gabor
name: Piccolo, Stephen R.
name: Johnson, W. Evan
name: Li, Dean Y.
name: Parker, Joel S.
name: Miller, Ryan H.
name: Moos, Philip J.
name: Reddy, Chakravarthy B.
name: Cohen, Adam L.
name: Bild, Andrea H.
name: Buys, Saundra S.
name: Brady, Samuel W.
name: Boltax, Jonathan P.
name: McQuerry, Jasmine A.
name: Esch, Amanda
name: Heiser, Laura M.
name: Selitsky, Sara R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Metastatic breast cancer remains challenging to treat, and most patients ultimately progress on therapy. This acquired drug resistance is largely due to drug-refractory sub-populations (subclones) within heterogeneous tumors. Here, we track the genetic and phenotypic subclonal evolution of four breast cancers through years of treatment to better understand how breast cancers become drug-resistant. Recurrently appearing post-chemotherapy mutations are rare. However, bulk and single-cell RNA sequencing reveal acquisition of malignant phenotypes after treatment, including enhanced mesenchymal and growth factor signaling, which may promote drug resistance, and decreased antigen presentation and TNF-α signaling, which may enable immune system avoidance. Some of these phenotypes pre-exist in pre-treatment subclones that become dominant after chemotherapy, indicating selection for resistance phenotypes. Post-chemotherapy cancer cells are effectively treated with drugs targeting acquired phenotypes. These findings highlight cancer's ability to evolve phenotypically and suggest a phenotype-targeted treatment strategy that adapts to cancer as it evolves.
Discovery of long-range inhibitory signaling to ensure single axon formation
Creators: name: Ishizawa, Naruki
name: Kaibuchi, Kozo
name: Xu, Chundi
name: Nakamuta, Shinichi
name: Hahn, Klaus M.
name: Namba, Takashi
name: Wu, Mengya
name: Amano, Mutsuki
name: Hamaguchi, Tomonari
name: Watanabe, Takashi
name: Takano, Tetsuya
name: Yura, Yoshimitsu
name: Naoki, Honda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: A long-standing question in neurodevelopment is how neurons develop a single axon and multiple dendrites from common immature neurites. Long-range inhibitory signaling from the growing axon is hypothesized to prevent outgrowth of other immature neurites and to differentiate them into dendrites, but the existence and nature of this inhibitory signaling remains unknown. Here, we demonstrate that axonal growth triggered by neurotrophin-3 remotely inhibits neurite outgrowth through long-range Ca 2+ waves, which are delivered from the growing axon to the cell body. These Ca 2+ waves increase RhoA activity in the cell body through calcium/calmodulin-dependent protein kinase I. Optogenetic control of Rho-kinase combined with computational modeling reveals that active Rho-kinase diffuses to growing other immature neurites and inhibits their outgrowth. Mechanistically, calmodulin-dependent protein kinase I phosphorylates a RhoA-specific GEF, GEF-H1, whose phosphorylation enhances its GEF activity. Thus, our results reveal that long-range inhibitory signaling mediated by Ca 2+ wave is responsible for neuronal polarization.Emerging evidence suggests that gut microbiota influences immune function in the brain and may play a role in neurological diseases. Here, the authors offer in vivo evidence from a Drosophila model that supports a role for gut microbiota in modulating the progression of Alzheimer's disease.
Cyathea lechleri Mett., Fil. Lechl.
Creators: name: Lehnert, Marcus
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Cyatheales
Cyatheaceae
Cyathea
Cyathea lechleri

description: Cyathea lechleri Mett., Fil. Lechl. 2. 32. 1859.
 Range: — Colombia to Bolivia (LP).
 Ecology: —Uncommon in montane rain forests, also with distinct dry seasons; uncommon, ususally close to ridges; 750–1560 m.
 Notes: —This name is often erroneously applied to other species of the sphaeropteroid indusiate group, mostly C. squamipes and C. delgadii. Cyathea lechleri is best described as a medium-sized tree fern without notable features: scurf is ephemeral and hairs are largely absent, petiole scales are of average size and non-descript brown color; the frond axes are abaxially smooth and dark brown but not conspicuously dark or shiny. The best defining character is the relatively small maximum size of the pinnules (5.0–7.0 × 1.1–1.8 cm), which are sessile to stalked 2.0(–3.0) mm and linear-oblong with weakly cordate bases and long acuminate apices. In other tall species, pinnules of that size are never stalked and have acute to shortly attenuate apices, and the largest pinnules exceed these measurements (>10 × 2 cm).
description: Published as part of Lehnert, Marcus & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. XX. Cyatheaceae, pp. 118-134 in Phytotaxa 334 (2) on page 127, DOI: 10.11646/phytotaxa.334.2.2, http://zenodo.org/record/13721436
Steering in-plane shear waves with inertial resonators in platonic crystals
Creators: name: Achaoui, Younes
name: Diatta, André
name: Guenneau, Sébastien
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: Numerical simulations shed light on control of shear elastic wave propagation in plates structured with inertial resonators. The structural element is composed of a heavy core connected to the main freestanding plate through tiny ligaments. It is shown that such a configuration exhibits a complete band gap in the low frequency regime. As a byproduct, we further describe the asymmetric twisting vibration of a single scatterer via modal analysis, dispersion and transmission loss. This might pave the way to new functionalities such as focusing and self-collimation in elastic plates.
title: A Victim of Success? Increasing Classified Revenue in a Declining Market: A Case Study in Barbados
Creators: name: Davis, Chay
Publisher: name: University of Liverpool Repository
Year: 2020

description: Abstract Main purpose This action research study investigates the extent to which a classified advertising manager at a leading newspaper publisher in Barbados sought to grow advertising revenue in an anemic economy in 2015, and 2016. The manager sought to achieve this growth by transitioning his sales team from a state of ad-taking, which is associated with ‘passivity’, ‘poor customer engagement’ and a ‘paucity of sales’, to one of adaptive selling, which is more ‘proactive’, ‘probing’ and ‘pioneering’ in both nature and scope. Research approach The researcher utilises a multi-method approach, which comprises a dominant quantitative paradigm and a supportive qualitative paradigm, where the former enabled the researcher to quantify the views among his classified advisors and advertisers to understand whether they were receptive towards adaptive selling practices, while the latter paradigm, helped shed light on anomalous data. Other supportive designs included document analysis, which gave the researcher voice and meaning into the phenomenon under investigation. Review of outcomes The findings of the study confirms that adaptive selling in the department under review helped its classified advisors increase their sales in an anemic economy during the periods 2015 and 2016. However, when an economy experienced severe contractions, coupled with an aggressive Government austerity programme, the data revealed that adaptive selling in itself was unable to increase sales among classified advisors, since advertiser spending was significantly restricted. The data from classified advisors reveals that commercial advertisers were more receptive to engaging adaptive selling, because it enabled them to fully capitalise on their advertising investment; while private advertisers, who placed obituary and in-memoriam notices were equally receptive to adaptive selling, because it enabled them to honour the legacy of their deceased relatives. These advertiser preferences helped to accrue incremental revenue for the department under review. Keywords: Adaptive selling, upselling and cross selling, worded and display advertisements, classified advisors, customised selling, anemic economy, and coaching.
IMPROVEMENT OF FEED EFFICIENCY IN DAIRY CATTLE
Creators: name: OMODEI ZORINI, FABIO
Publisher: name: Universit� degli Studi di Milano
Year: 2021

description: The improvement of feed efficiency in dairy cattle has traditionally been approached through an increase in production levels. However, the effectiveness of the energy partitioning underlying the dilution of maintenance phenomenon decreases with each successive increment in production relative to body size, and therefore will lose importance in the next years. The selection of more efficient animals (i.e. animals that consume less feed to achieve a fixed production) is limited by the cost and inherent difficulty in recording individual feed intake data, which prove pivotal to improve the accuracy of the estimated breeding values for feed efficiency traits. First aim of my project was to record and collect individual phenotypic data on the dry matter intake of dairy cattle under different dietary conditions and at different production stages. The collected data will become part of a larger collaborative dataset aimed at increasing the prediction power of genomic selection plans including traits related to the feed efficiency. Furthermore, following a multimodal approach essential for an effective improvement of the dairy enterprise efficiency, the effect of feed additives and alternative feed ingredients on the production, health status and efficiency of dairy cattle has been investigated. In the first trial, the effect of camelina cake ? a byproduct of camelina oil rich in proteins and unsaturated fatty acids ? on milk fatty acid profile was investigated. Results from the study evidenced a higher concentration of n-3 PUFA (p = 0.02) and a lower n-6/n-3 ratio (p = 0.01) in the milk of cows fed camelina compared to control. The analysis of the ruminal content suggested a moderate effect of camelina on the ruminal environment and biochemistry. In the second trial, the effect of Saccharomyces cerevisiae (live yeast) on the ruminal environment and its interaction with the production and health status of dairy cows was investigated. Dietary treatment with S. cerevisiae did not affect the investigated ruminal parameters and had only mild effects on blood biochemistry. However, an effect on the ruminal pH was observed when cows were fed low-quality forages, with higher pH values in cows supplemented with S. cerevisiae compared to control (p < 0.05). In the last trial, the effect of camelina on the ruminal microbial populations and the cumulus-oocyte complexes of growing dairy heifers was evaluated. The inclusion of camelina in the diet was associated with higher expression of all selected molecular markers of oocyte quality (p < 0.05). Moreover, feeding camelina affected the ruminal microbiota, as shown by the significant reduction in the alpha diversity of the treatment group (p < 0.05).
Sample Size Guidance for External Randomised Controlled Pilot Trials: A Protocol for a Methodological Systematic Review - Addendum 31 Oct 22
Creators: name: Eddy, Saskia
name: Parker, Kitty
name: Robinson, Clare
name: Eldridge, Sandra
name: Lancaster, Gillian
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Statistics and Probability
subject: Physical Sciences and Mathematics
subject: Clinical Trials
subject: Vital and Health Statistics
subject: Biostatistics
subject: clinical trial
subject: clinical trials
subject: feasibility
subject: feasibility study
subject: feasibility trial
subject: methodological systematic review
subject: methodology
subject: PAFS
subject: pilot
subject: pilot study
subject: pilot trial
subject: sample size
subject: study
subject: systematic review
subject: trial

description: This registration contains the protocol for a methodological systematic review about sample size justifications for external randomised controlled pilot trials. This methodological systematic review is part of a larger programme of work to provide guidance to help health researchers choose an appropriate sample size for their external randomised controlled pilot trials. Professor Sandra Eldridge and Professor Gillian Lancaster are joint last authors on this protocol.
Ubaldino Peruzzi a … (26 aprile 1874)
Creators: name: Peruzzi, Ubaldino
Publisher: name: Zenodo
Year: 2023
Subjects: Accademia dei Georgofili
Peruzzi, Ubaldino
Lettera
Letter
Carteggio
Correspondence
1874

description: Lettera di Ubaldino Peruzzi a ... del 26 aprile 1874. Segnatura dell’unità documentale: Archivio storico dell’Accademia dei Georgofili, Carteggio, Busta 36, 4857. Natura: manoscritto. Consistenza: cc. 2
description: Digitalizzato come parte della Mostra virtuale: Ubaldino Peruzzi : un percorso in rete : in occasione del bicentenario della nascita https://www.georgofili.it/contenuti/ubaldino-peruzzi-un-percorso-in-rete/17485
Cyathea mucilagina R. C. Moran, Novon
Creators: name: Lehnert, Marcus
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Cyatheales
Cyatheaceae
Cyathea
Cyathea mucilagina

description: Cyathea mucilagina R.C.Moran, Novon 1: 92. 1991.
 Range: — Costa Rica and Panama; Colombia to Bolivia (CO).
 Ecology: —Rare in understory of montane forests, along woodland streams and in protected gorges; 910 m in Bolivia, 400–1500 m elsewhere.
 Notes: —This species combines some rare characters among scaly tree ferns, i.e. green alate petioles and rachises that are hairy on both sides, mucilage covering unexpanded croziers and barely indurated petioles that are bendable like celery or rhubarb.
description: Published as part of Lehnert, Marcus & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. XX. Cyatheaceae, pp. 118-134 in Phytotaxa 334 (2) on page 128, DOI: 10.11646/phytotaxa.334.2.2, http://zenodo.org/record/13721436
title: Accountability in Responses to Natural Disasters: A Case Study of Flooding in Garut, West Java, Indonesia
Creators: name: Suryaman, Yaman
Publisher: name: University of Liverpool Repository
Year: 2020

description: This study assesses how accountability is practiced and justified in collaboration of cross-sector organisations and community. It addresses three main questions: firstly, what are the roles of actors in collaborative working setting of repeated flooding, where government organisations and non-government organisations, civil society groups, and individuals all work together in dealing with this recurring issue; secondly, what is working relationship between different actors in four phases of disaster management; and thirdly, how does accountability arrangement affect actions in every disaster phase. These three questions are addressed through case study approach conducted between 2015-2019. The research involves qualitative analysis of collected data from field work and semi-structured interviews with actors who involve in disaster management. This data is complemented by document analysis. There is a contrast in the response to disaster management between the state and some communities and local NGOs. The communities and local NGOs respond to natural disaster according to their ancestral beliefs and knowledge about their relationship with nature. In contrast, local government institutions often execute transactional projects which are measured by results of short-term activities. Local communities use their knowledge from generation to generation in preserving and treating nature as part of their life but this does not inform government activities in the development of the natural environment (e.g, farming and tourism sectors). This study finds that accountability concept is recognised differently by the state (local government of Garut officers) and people, including NGOs and donors. The state defines accountability as a hierarchical mechanism which is manifested in the form of reports to higher authority within state system. However, accountability in disaster management has different aspects including the natural environment as an actor. Nature has a significant influence in understandings of the concept of accountability in disaster responses. There are two types of accountability within this context. Accountability between actors which is influenced by nature and between actors with nature. The first accountability type is a negotiable accountability and the second accountability type is non-negotiable type of accountability. Understandings of accountability in developing countries needs to engage with the idea of the prismatic society and recognize the experience of colonization.
Lepton Flavor and Non-Universality from Minimal Composite Higgs Setups
Creators: name: Carmona, Adrian
name: Goertz, Florian
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present a new class of models of lepton flavor in the composite Higgs framework. Following the concept of minimality, they lead to a rich phenomenology in good agreement with the current experimental picture. Because of a unification of the right-handed leptons, our scenario is very predictive and can naturally lead to a violation of lepton-flavor universality in neutral current interactions. We will show that, in particular, the anomaly in $R_K= {\cal B}(B \to K μ^+ μ^-)/{\cal B}(B \to K e^+ e^-)$, found by LHCb, can be addressed, while other constraints from quark- and lepton-flavor physics are met. In fact, the minimal structure of the setup allows for the implementation of a very powerful flavor protection, which avoids the appearance of new sources of flavor-changing neutral currents to very good approximation. Finally, the new lepton sector provides a parametrically enhanced correction to the Higgs mass, such that the need for ultra-light top partners is weakened considerably, linking the mass of the latter with the size of the neutrino masses.
description: 5 pages, 3 figures; v2: matches version published in Physical Review Letters, for some slightly extended discussions see v1
AMMONIA EMISSIONS FROM ARABLE LANDS IN PO VALLEY: METHODOLOGIES, DYNAMICS AND QUANTIFICATION.
Creators: name: CAROZZI, MARCO
Publisher: name: Universit� degli Studi di Milano
Year: 2012

description: Although the Po Valley (north Italy) is considered one of the most important ammonia (NH3) emitting regions in Europe, few data are available for an evaluation of the ammonia budget at field level in arable lands. Here the NH3 losses were quantify, considering different measurement and estimation approach, fertilisers and agronomic managements. The outputs of two concentration based-inverse dispersion models, together a mechanistic model were assessed with the direct measurements of ammonia fluxes by the micrometeorological technique eddy covariance, at hourly, daily and seasonal scales. A discussion on advantages, disadvantages and performances of each model is given in order to determine the most suitable method able to evaluate the ammonia emission in Po Valley at field scale. The selected inverse dispersion models were assessed in their uncertainty to quantify ammonia emissions rates, and their significance with regards to the Italian context. Moreover emissions from cattle slurry and urea application were performed in seven field trials in three different locations of Po Valley, in order to evaluate the best practices in reducing NH3 loss from arable land. The emission factors relative to different agronomical practices (slurry injection, slurry surface spreading with and without incorporation, urea surface spreading) are given, taking into account the main factors affecting the NH3 volatilization phenomenon and describing its dynamics.
Interaction-induced conductance from zero modes in a clean magnetic graphene waveguide
Creators: name: Cohnitz, Laura
name: Häusler, Wolfgang
name: Zazunov, Alex
name: Egger, Reinhold
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We consider a waveguide formed in a clean graphene monolayer by a spatially inhomogeneous magnetic field. The single-particle dispersion relation for this waveguide exhibits a zero-energy Landau-like flat band, while finite-energy bands have dispersion and correspond, in particular, to snake orbits. For zero-mode states, all matrix elements of the current operator vanish, and a finite conductance can only be caused by virtual transitions to finite-energy bands. We show that Coulomb interactions generate such processes. In stark contrast to finite-energy bands, the conductance is not quantized and shows a characteristic dependence on the zero-mode filling. Transport experiments thereby offer a novel and highly sensitive probe of electron-electron interactions in clean graphene samples. We argue that this interaction-driven zero-mode conductor may also appear in other physical settings and is not captured by the conventional Tomonaga-Luttinger liquid description.
description: 14 pages, 8 figures, published version
THE OFD1 PROTEIN CONTROLS AUTOPHAGOSOME BIOGENESIS THROUGH SELECTIVE AUTOPHAGY
Creators: name: BRILLANTE, SIMONA
Publisher: name: Universit� degli Studi di Milano
Year: 2020

description: Cilia are cellular projections that serve a wide variety of essential functions in mammals. Defects in cilia structure or function have emerged as etiological mechanisms underpinning human diseases called ciliopathies. The OFD1 gene, defective in a rare developmental ciliopathy known as Oral facial digital syndrome type I, encodes for a centrosomal/basal body protein required for cilia formation. Recent data link ciliary structures to autophagy, the major intracellular degradation system, although the mechanisms and the main players underlying this connection are still to be determined. Autophagy is an evolutionarily conserved and strictly regulated lysosomal pathway which plays a wide variety of physiological and pathophysiological roles in cellular homeostasis. Either too little or too much autophagy may contribute to pathological conditions. In the past decade a great deal of progress has been made in the molecular dissection of stimulatory autophagy inputs. On the other hand, our understanding of the mechanisms that restrain autophagy is only partial and far from being complete. Data obtained during my PhD program contribute to the description of a new negative feedback mechanism that inhibits autophagosome biogenesis through selective autophagy-mediated degradation of ATG13, a component of the ULK1 autophagy initiation complex. I demonstrate that the ciliary OFD1 protein is involved in selective autophagy and acts as autophagy receptor for ATG13 via direct interaction with the Atg8/LC3/GABARAP family of proteins. Preliminary data also indicate that excessive autophagy may contribute to the disease pathogenesis. My results add a new tile to the puzzle of the cilia/autophagy interconnection and will help shedding light on these complex biological processes.
Wideband superconducting nanotube electrometer
Creators: name: Häkkinen, Pasi
name: Fay, Aurélien
name: Golubev, Dmitry
name: Lähteenmäki, Pasi
name: Hakonen, Pertti
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We have investigated the microwave response of nanotube Josephson junctions at 600-900 MHz at microwave powers corresponding to currents from 0 to $2\times I_{\mathrm C}$ in the junction. Compared with theoretical modeling, the response of the junctions correspond well to the lumped element model of resistively and capacitively shunted junction. We demonstrate the operation of these superconducting FETs as charge detectors at high frequencies without any matching circuits. Gate-voltage-induced charge $Q_{\rm G}$ modifies the critical current $I_{\rm C}$, which changes the effective impedance of the junction under microwave irradiation. This change, dependent on the transfer characteristics $dI_{\mathrm C}/dQ_{\rm G}$, modifies the reflected signal and it can be used for wide band electrometry. We measure a sensitivity of $3.1\times10^{-5}$ $e/\sqrt{\mathrm{Hz}}$ from a sample which has a maximum switching current of 2.6 nA.
description: 4 pages, 4 figures
Cyathea obnoxia Lehnert, Brittonia
Creators: name: Lehnert, Marcus
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Cyatheales
Cyatheaceae
Cyathea
Cyathea obnoxia

description: Cyathea obnoxia Lehnert, Brittonia 58(1): 4. 2006.
 Range: — Colombia to Bolivia (LP).
 Ecology: —Rare in the understory of montane rainforests, usually in small groups in gorges; 2680 m.
 Notes: —In this species, the pinnae are ± opposite in the proximal half of the lamina but may be alternate towards the apex. The hairy petioles and the large and wide, orange-brown scales are distinctive.
description: Published as part of Lehnert, Marcus & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. XX. Cyatheaceae, pp. 118-134 in Phytotaxa 334 (2) on page 128, DOI: 10.11646/phytotaxa.334.2.2, http://zenodo.org/record/13721436
title: Large-scale quantification of Li in spodumene pegmatite using Laser Induced Breakdown Spectroscopy
Creators: name:  Müller ,  Simon
name:  Meima ,  Jeannet
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Spatially detailed surface analysis of geological samples and drill cores offers insight into element and mineral distributions on large scales, an important information in ore exploration processes. Laser Induced Breakdown Spectroscopy (LIBS) is an uprising technology that allows fast in-situ geochemical measurements directly on a sample surface under atmospheric conditions. Since nearly no sample preparation is needed, the technology is suitable for spatially-resolved measurements on large samples such as drill cores. LIBS also allows the detection of light elements like Li, an important element due to the increasing amounts needed for battery production of all kinds. Nevertheless, interpreting LIBS data is challenging, since various physical and chemical matrix effects do not allow a straightforward analysis of heterogeneous material. Especially quantification remains problematic. We used a LIBS drill core scanner (Nd:YAG Q-switched 20Hz 1064nm laser and a high-resolution 285-964nm Echelle spectrometer) for 1D profile measurements of 10 consecutive drill core meters from the Rapasaari Li-deposit in Finland. The deposit covers Li-bearing spodumene and muscovite pegmatite, from which five large samples were measured with high resolution in 2D, as well. Small-scale ICP-MS mappings were used as pixel-matched quantitative reference measurements of Li concentrations. They were successfully co-registrated with the LIBS measurements, which enabled matrix-matched quantification using chemometric quantification models.
Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling
Creators: name: Philpot, Benjamin D.
name: Bigler, Rebecca L.
name: Taylor, Anne Marion
name: Nagendran, Tharkika
name: Nudo, Randolph J.
name: Larsen, Rylan S.
name: Frost, Shawn B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Injury of CNS nerve tracts remodels circuitry through dendritic spine loss and hyper-excitability, thus influencing recovery. Due to the complexity of the CNS, a mechanistic understanding of injury-induced synaptic remodeling remains unclear. Using microfluidic chambers to separate and injure distal axons, we show that axotomy causes retrograde dendritic spine loss at directly injured pyramidal neurons followed by retrograde presynaptic hyper-excitability. These remodeling events require activity at the site of injury, axon-to-soma signaling, and transcription. Similarly, directly injured corticospinal neurons in vivo also exhibit a specific increase in spiking following axon injury. Axotomy-induced hyper-excitability of cultured neurons coincides with elimination of inhibitory inputs onto injured neurons, including those formed onto dendritic spines. Netrin-1 downregulation occurs following axon injury and exogenous netrin-1 applied after injury normalizes spine density, presynaptic excitability, and inhibitory inputs at injured neurons. Our findings show that intrinsic signaling within damaged neurons regulates synaptic remodeling and involves netrin-1 signaling.Spinal cord injury can induce synaptic reorganization and remodeling in the brain. Here the authors study how severed distal axons signal back to the cell body to induce hyperexcitability, loss of inhibition and enhanced presynaptic release through netrin-1.
TASO - Face-to-face Summer schools RCT - March 2022
Creators: name: The Centre For Transforming Access And Student Outcomes In Higher Education (TASO)
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Education
subject: Higher Education
subject: Social and Behavioral Sciences
subject: Inequality and Stratification
subject: Sociology
subject: FOS: Sociology

description: New version of TP for summer schools RCT. This RCT tests whether summer schools are effective interventions to widen participation in HE. This is an extension of a previous project which, due to the covid-19 pandemic, measured the impact of online summer schools. This year the summer schools will be delivered face-to-face therefore the project has been renewed to include these.