cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Determining, Treating, and Preventing Mechanisms of Sudden Death in Epilepsy using Medical Implantable Devices
Creators: name: Pederson, Daniel J.
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Electrical engineering not elsewhere classified
Biomechanical engineering
Digital processor architectures
Other information and computing sciences not elsewhere classified

description: People with epilepsy have an increased risk of mortality when compared to the general population. These increased mortality risks include deaths related to status epilepticus and sudden unexpected death in epilepsy (SUDEP). Physiological data describing cardiac, respiratory, and brain function prior to sudden death in epilepsy is crucial to the studying the underlying mechanisms behind these deaths. Because it is unknown when sudden deaths in epilepsy may occur, continuous monitoring is necessary to guarantee the capture of physiological data prior to death. I have used custom designed implantable devices to continuously measure cardiac, respiratory, and neurological signals in freely behaving rats with chronically induced epilepsy. Due to the continuous respiration measurements, the resultant dataset is the first of its kind. This dataset indicates that respiratory abnormalities (reduced respiration and short apneas) occur during and after seizures. These abnormalities may indicate SUDEP onset because obstructive apneas due to laryngospasm have been indicated as possible causes of SUDEP in other studies. Laryngospasms can be caused by gastric acid coming into contact with the larynx. During a laryngospasm, intrinsic laryngeal muscles contract, resulting in the closure of the airway. Recently published research has indicated that acid reflux may be responsible for triggering fatal laryngospasms in rats with induced seizures. I have found that the larynx can be opened during a laryngospasm by electrically stimulating the recurrent laryngeal nerves. I have also found that performing gastric vagotomies leads to a statistically significant reduction in mortality due to fatal apneas in rats with induced seizures.
sj-pdf-2-tar-10.1177_17534666211028077 – Supplemental material for Clinical effectiveness of convalescent plasma in hospitalized patients with COVID-19: a systematic review and meta-analysis
Creators: name: Abeldaño Zuñiga, Roberto Ariel
name: González-Villoria, Ruth Ana María
name: Elizondo, María Vanesa
name: Osorio, Anel Yaneli Nicolás
name: Martínez, David Gómez
name: Coca, Silvia Mercedes
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 110203 Respiratory Diseases

description: Supplemental material, sj-pdf-2-tar-10.1177_17534666211028077 for Clinical effectiveness of convalescent plasma in hospitalized patients with COVID-19: a systematic review and meta-analysis by Roberto Ariel Abeldaño Zuñiga, Ruth Ana María González-Villoria, María Vanesa Elizondo, Anel Yaneli Nicolás Osorio, David Gómez Martínez and Silvia Mercedes Coca in Therapeutic Advances in Respiratory Disease
Additional file 1 of Establishing gaze markers of perceptual load during multi-target visual search
Creators: name: Harris, Anthony M.
name: Eayrs, Joshua O.
name: Lavie, Nilli
Publisher: name: figshare
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Additional file 1. Analysis of fixation duration and saccade amplitude for each load condition in Experiments 1 and 2, broken down by within-trial time, and time across the experiment.
A Study on the Operation of Gerotor Type Units Considering Fluid Structure and Mechanical Interaction Effects
Creators: name: Pellegri, Matteo
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified
Fluid mechanics and thermal engineering not elsewhere classified

description: Gerotor units are widely used in low-pressure (up to 30 bar) fluid power applications, injection and lubrication systems, due to their compact package and low cost. Their performance in terms of volumetric efficiency, flow pulsations, internal pressure peaks or localized cavitation depends on many parameters, such as the rotors profi les and the manufacturing tolerances. In this work, a multi-domain simulation approach for the numerical analysis of the performance of Gerotor units is proposed. The model can be used for analysis and virtual prototyping of units considering the actual geometry of the rotors, their geometrical tolerances and the properties of the working fluid and materials.
The approach is based on the coupling of different models: a numerical geometric model evaluating the instantaneous volumes and flow areas inside the unit; a lumped parameter fluid dynamic model describing the displacing process of the tooth space volumes; and a mechanical model evaluating the internal micro-motions of the rotors axes according to their tolerances. In this way, the model determines the actual loading of the rotors, considering also the actual location of the points of contact. Advanced 2D CFD models for the analysis of lubricated interfaces have been developed to study the axial and the radial gaps. This approach allows an accurate prediction of the power losses and radial micro-motion of the rotors taking into account fluidstructure interaction effects. A line contact model is used to describe the contact interface using an elastohydrodynamic approach and non-Newtonian fluid behavior for the prediction of the friction between the rotors.
Speci c experiments were performed by connecting the pump outlet to a variable loading orifi ce and by measuring the delivered flow, pressure ripple and required torque under dfferent operating conditions of speed and outlet pressure. These experiments allowed a detailed model validation through the comparisons with simulation data in terms of signi cant steady-state as well as transient pressure, flow and torque features. After the model validation, gaps compensation solutions to minimize the volumetric losses are developed and studied showing the potential improvements on the performances of a prototype unit by reaching up to 55% volumetric effciency at high pressure (pmax > 100bar).
The approach used in the current work along with its proven accuracy through experiments can be considered a valuable tool when studying the impact of real-life technological clearances and gears geometry on the fluid-dynamic performance of the pump.
Pipasic: similarity and expression correction for strain-level identification and quantification in metaproteomics
Creators: name: Penzlin, Anke
name: Lindner, Martin S.
name: Döllinger, Jörg
name: Dabrowski, Piotr Wojtek
name: Nitsche, Andreas
name: Renard, Bernhard Y.
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2014
Subjects: subject: Algorithms
subject: Mass Spectrometry
subject: Software
subject: Peptides/chemistry
subject: Bacterial Proteins/metabolism
subject: Environmental Microbiology
subject: Cowpox virus/classification
subject: Proteome/chemistry
subject: Proteome/metabolism
subject: Proteomics/methods
subject: 610 Medizin

description: Motivation: Metaproteomic analysis allows studying the interplay of organisms or functional groups and has become increasingly popular also for diagnostic purposes. However, difficulties arise owing to the high sequence similarity between related organisms. Further, the state of conservation of proteins between species can be correlated with their expression level, which can lead to significant bias in results and interpretation. These challenges are similar but not identical to the challenges arising in the analysis of metagenomic samples and require specific solutions. Results: We introduce Pipasic (peptide intensity-weighted proteome abundance similarity correction) as a tool that corrects identification and spectral counting-based quantification results using peptide similarity estimation and expression level weighting within a non-negative lasso framework. Pipasic has distinct advantages over approaches only regarding unique peptides or aggregating results to the lowest common ancestor, as demonstrated on examples of viral diagnostics and an acid mine drainage dataset.
sj-pdf-6-tar-10.1177_17534666211028077 – Supplemental material for Clinical effectiveness of convalescent plasma in hospitalized patients with COVID-19: a systematic review and meta-analysis
Creators: name: Abeldaño Zuñiga, Roberto Ariel
name: González-Villoria, Ruth Ana María
name: Elizondo, María Vanesa
name: Osorio, Anel Yaneli Nicolás
name: Martínez, David Gómez
name: Coca, Silvia Mercedes
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 110203 Respiratory Diseases

description: Supplemental material, sj-pdf-6-tar-10.1177_17534666211028077 for Clinical effectiveness of convalescent plasma in hospitalized patients with COVID-19: a systematic review and meta-analysis by Roberto Ariel Abeldaño Zuñiga, Ruth Ana María González-Villoria, María Vanesa Elizondo, Anel Yaneli Nicolás Osorio, David Gómez Martínez and Silvia Mercedes Coca in Therapeutic Advances in Respiratory Disease
Additional file 2 of Changes in body mass index and behavioral health among adolescents in military families during the COVID-19 pandemic: a retrospective cohort study
Creators: name: Koehlmoos, Tracey Pérez
name: Madsen, Cathaleen
name: Banaag, Amanda
name: Adirim, Terry
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file 2: Supplemental Figure 2. Prevalence and Percent Change in Obesity by Race.
Modeling Boundary Effect Problems of Heterogeneous Structures by Extending Mechanics of Structure Genome
Creators: name: Peng, Bo
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Composite and hybrid materials
Aerospace structures
Aerospace materials

description: First, the theory of MSG is extended to aperiodic heterogeneous solid structures. Integral constraints are introduced to decompose the displacements and strains of the heterogeneous material into a fluctuating part and a macroscopic part, of which the macroscopic part represents the responses of the homogenized material. One advantage of this theory is that boundary conditions are not required. Consequently, it is capable of handling micro-structures of arbitrary shapes. In addition, periodic constraints can be incorporated into this theory as needed to model periodic or partially periodic materials such as textile composites. In this study, the newly developed method is employed to investigate the finite thickness effect of textile composites.
Second, MSG is enabled to deal with Timoshenko beam-like structures with spanwise heterogeneity, which provide higher accuracy than the previous available Euler–Bernoulli beam model. Its reduced form, the MSG beam cross sectional analysis, is found to be able to analyze generalized free-edge problems with arbitrary layups and subjected to general loads. In this method, the only assumption applied is that the laminate is long enough so that the Saint-Venant principle can be adopted. There is no limitation on the cross section of the laminate since no ad hoc assumption is involved with the microstructure geometry. This method solve the free-edge problem from a multiscale simulation point of view.
Wikidata As Authority Linking Hub
Creators: name: Neubert, Joachim
name: Voß, Jakob
Publisher: name: Zenodo
Year: 2017
Subjects: Wikidata
knowledge organization systems
Concordances

description: Neben allgemeinen Informationen zu Objekten aller Art enthält die freie Datenbank Wikidata Mappings zu mehr als 1.000 verschiedenen Normdateien. Der Vortrag zeigt, wie diese Mappings erstellt und genutzt werden können. Dies beinhaltet zunächst eine Übersicht von Besonderheiten und Voraussetzungen zur Verwendung von Wikidata als Normdatei (freie Bearbeitung, Auswahl von Properties ...). Anschließend werden Abfragemöglichkeiten gezeigt, um Normdaten-Verknüpfungen und andere Informationen aus Wikidata zu extrahieren (SPARQL, BEACON, Wikidata-Clients...). Schließlich wird anhand von Mapping-Projekten von ZBW und VZG demonstriert, wie Mappings in Wikidata mit Hilfe von Werkzeugen erstellt werden können (Mix'n'match, wdmapper...) und sich eigene Daten abgleichen lassen.
Epidemiology of Giardia duodenalis infection in ruminant livestock and children in the Ismailia province of Egypt: insights by genetic characterization
Creators: name: Helmy, Yosra A.
name: Klotz, Christian
name: Wilking, Hendrik
name: Krücken, Jürgen
name: Nöckler, Karsten
name: Samson-Himmelstjerna, Georg Von
name: Zessin, Karl-H.
name: Aebischer, Toni
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2014
Subjects: subject: Giardia
subject: Genetic characterization
subject: Ruminants
subject: Diarrheal children
subject: Real time PCR
subject: RIDA®QUICK test
subject: Triose phosphate isomerase (tpi)
subject: Glutamate dehydrogenase (gdh)
subject: β-giardin (bg)
subject: Spatial distribution
subject: Egypt
subject: 610 Medizin

description: Background: Giardia duodenalis is a common flagellated protozoan parasite that infects the small intestine of a wide range of vertebrate hosts. This study aimed to determine whether tracing of G. duodenalis isolates by current genetic typing tools is possible using an exemplary set of samples from infected cattle, buffalo and children from the Ismailia province, Egypt. Method: A total of 804 fecal samples from ruminant animals was collected from 191 herds and 165 samples from diarrheal children below the age of 10 years. Parasites were detected in these samples using the copro-antigen RIDA®QUICK test and by real-time PCR. Samples were then genetically characterized based on the triosephosphate isomerase, glutamate dehydrogenase and β-giardin genes. Results: The prevalence of G. duodenalis was 53% in ruminants and 21% in symptomatic children and infection was not positively correlated with diarrheal symptoms. Sequence typing analysis confirmed predominance of B-type sequences (>67%) in humans and E-type sequences (>81%) in ruminants over A-type sequences. For 39 samples the complete sequence information of the three marker gene fragments could be derived. Integration of the concatenated sequence information of the three marker gene fragments with the spatial data of the respective sample revealed that identical or near identical (only up to 1 out of 1358 bp different) concatenated sequencing types were spatially related in 4 out of 5 cases. Conclusion: The risk of zoonotic infection emanating from ruminants even in high prevalence areas is negligible. Genetic characterization indicated a predominant anthropogenic cycle of infection within the pediatric population studied. Integration of sequence typing data with information on geographic origins of samples allows parasite sub-population tracing using current typing tools.
Advanced Characterization of Glucan Particulates: Small-granule Starch, Retention of Small Molecules, and Local Architecture Defined by Molecular Rotor
Creators: name: Peng, Xingyun
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Food chemistry and food sensory science
Food sciences not elsewhere classified

description: The discovery and utilization of novel starches with unique superb properties are highly demanded for modern industrial uses. Small-granule starch (SGS) is a category of unconventional starches with the granular size smaller than 10 μm. The potential use of SGS includes many conventional and novel high-value applications, such as texturizing, fat replacement, encapsulation, controlled delivery and nano-engineering. In the present work, we focused on three SGS isolated from amaranth (Amaranth cruentus), cow cockle (Saponaria vaccaria) and sweet corn (sugary-1 maize mutant). The basic structural and unique physical properties of SGS were characterized and compared to common large-granule food starches. It was found that (1) the highly branched amylopectin contributed to low crystallinity and pasting viscosities of sweet corn starch, (2) cow cockle starch exhibited high shear-resistance and low retrogradation in prolonged storage, and (3) the amylopectin for amaranth starch was less branched with small clusters, which was associated with the high crystallinity, medium shear-resistance and low pasting viscosity of amaranth starch. Despite the small size of starch granules, SGS in both native and swelling states showed the capacity of retaining small molecules. Compared to large-granule starch, native SGS are more difficult for small molecules to reach an equilibrium permeation. This work provides insights to the fine structure and physicochemical behaviors of selected high-potent SGS, which is believed to support the industrial production and application of SGS in the future. The characteristics of local polymeric structure dominate many critical properties of glucan particles, such as starch retrogradation and the loading and stabilizing of active substance. Molecular rotor (MR), a fluorescent probe, was proposed to fulfill the simple, high-sensitive, and quantitative-based characterization of local glucan architecture (LGA). In the present work, two innovative studies relevant to this novel method were conducted: (1) MR was able to characterize glucans based on its unique fluorescent response to characteristic LGA, (2) MR was able to sensitively probe and visually demonstrate the transition of LGA induced by starch retrogradation. This novel MR-based approach is expected to advance carbohydrate-related researches in the future.
Additional file 1 of Changes in body mass index and behavioral health among adolescents in military families during the COVID-19 pandemic: a retrospective cohort study
Creators: name: Koehlmoos, Tracey Pérez
name: Madsen, Cathaleen
name: Banaag, Amanda
name: Adirim, Terry
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file 1: Supplemental Figure 1. Prevalence and Percent Change in Underweight BMI by Race.
HIGH-THROUGHPUT IDENTIFICATION OF ONCOGENIC TYROSINE KINASE SUBSTRATE PREFERENCES TO IMPROVE METHODS OF DETECTION
Creators: name: Perez, Minervo
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Biochemistry and cell biology not elsewhere classified
Enzymes
Proteomics and intermolecular interactions (excl. medical proteomics)
Proteins and peptides

description: The use of computational approaches to understand kinase substrate preference has been a powerful tool in the search to develop artificial peptide probes to monitor kinase activity, however, most of these efforts focus on a small portion of the human kinome. The use of high throughput techniques to identify known kinase substrates plays an important role in development of sensitive protein kinase activity assays.The KINATEST-ID pipeline is an example of a computational tool that uses known kinase substrate sequence information to identify kinase substrate preference. This approach was used to design three artificial substrates for ABL, JAK2 and SRC family kinases. These biosensors were used to design ELISA and lanthanide-based assays to monitor in vitro kinase activity. The KINATEST-ID pipeline relies on a high number of reported kinase substrates to predict artificial substrate sequences, however, not all kinases have the sufficient number of known substrates to make an accurate prediction. The adaptation of kinase assay linked with phosphoproteomics technique was used to increase the number of known FLT3 kinase variant substrate sequences. Subsequently, a set of data formatting tools were developed to curate the mass spectrometry data to become compatible with a command line version of the KINATEST-ID pipeline modules. This approach was used to design seven pan-FLT3 artificial substrate (FAStides) sequences. The pair of FAStides that were deemed the most sensitive toward FLT3 kinase phosphorylation were assayed in increasing concentrations of clinically relevant tyrosine kinase inhibitors. To improve the automation of the mass spectrometry data analysis and formatting for use with the KINATEST-ID pipeline, a streamlined process was developed within a bioinformatic platform, GalaxyP. The data formatting tools used to process the FLT3 mass spectrometry data were converted into compatible versions to execute within the GalaxyP framework. This process was used to design four BTK artificial substrates (BAStide) to monitor kinase activity. Additionally, one of the BAStide sequences was designed in the lanthanide chelating motif to develop an antibody-free activity assay for BTK. Lastly, a multicolored time resolved lanthanide assay was designed by labeling SYK artificial substrate and a SRC family artificial substrate to measure the activity of both kinases in the same kinase reaction. This highlighted the functionality of lanthanide-based time resolved assays for potential multiplexing assay development.
Additional file 4 of Changes in body mass index and behavioral health among adolescents in military families during the COVID-19 pandemic: a retrospective cohort study
Creators: name: Koehlmoos, Tracey Pérez
name: Madsen, Cathaleen
name: Banaag, Amanda
name: Adirim, Terry
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file 4: Table S2. Percent Change in the Number of Adolescents with a Behavioral Health Diagnoses by Race.
Absence of Frequent Herpesvirus Transmission in a Nonhuman Primate Predator-Prey System in the Wild
Creators: name: Murthy, Sripriya
name: Couacy-Hymann, Emmanuel
name: Metzger, Sonja
name: Nowak, Kathrin
name: Nys, Helene De
name: Boesch, Christophe
name: Wittig, Roman
name: Jarvis, Michael A.
name: Leendertz, Fabian
name: Ehlers, Bernhard
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2013
Subjects: subject: Animals
subject: Humans
subject: Phylogeny
subject: Colobus/genetics
subject: Colobus/virology
subject: DNA Viral/genetics
subject: Ecosystem
subject: Herpesviridae/classification
subject: Herpesviridae/genetics
subject: Herpesviridae/pathogenicity
subject: Herpesviridae Infections/genetics
subject: Herpesviridae Infections/transmission
subject: Herpesviridae Infections/virology
subject: Pan troglodytes/genetics
subject: Pan troglodytes/virology
subject: Predatory Behavior
subject: Primates/virology
subject: 610 Medizin

description: Emergence of viruses into the human population by transmission from nonhuman primates (NHPs) represents a serious potential threat to human health that is primarily associated with the increased bushmeat trade. Transmission of RNA viruses across primate species appears to be relatively frequent. In contrast, DNA viruses appear to be largely host specific, suggesting low transmission potential. Herein, we use a primate predator-prey system to study the risk of herpesvirus transmission between different primate species in the wild. The system was comprised of western chimpanzees (Pan troglodytes verus) and their primary (western red colobus, Piliocolobus badius badius) and secondary (black-and-white colobus, Colobus polykomos) prey monkey species. NHP species were frequently observed to be coinfected with multiple beta- and gammaherpesviruses (including new cytomegalo- and rhadinoviruses). However, despite frequent exposure of chimpanzees to blood, organs, and bones of their herpesvirus-infected monkey prey, there was no evidence for cross-species herpesvirus transmission. These findings suggest that interspecies transmission of NHP beta- and gammaherpesviruses is, at most, a rare event in the wild.
Additional file 1 of Segmentation characteristics of deep, low-frequency tremors in Shikoku, Japan using machine learning approaches
Creators: name: Chen, Kate Huihsuan
name: Chiu, Hao-Yu
name: Obara, Kazushige
name: Liu, Yi-Hung
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer

description: Additional file 1: Text S1. Feature extraction dataset. Figure S1. The example of original tremor waveforms. Figure S2. The example of the autocorrelation function. Figure S3. The example of the band-pass filtered waveforms. Figure S4. The example of the evolution of the Discrete Fourier Transform. Figure S5. The examples of features ACF1/3 and ACF2/3. Figure S6. The example of feature NPks BP2–8 Hz. Figure S7. The example of NPks_DFTmean and NPks_DFTme. Figure S8. The result of four-class classification model.
Supplemental Material, sj-pdf-1-mns-10.1177_20592043211012396 - The Perception of Musical Expression in the Nineteenth Century: The Case of the Glorifying Hymnic*
Creators: name: Hentschel, Frank
name: Kreutz, Gunter
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 190406 Music Composition
subject: FOS: Arts (arts, history of arts, performing arts, music)
subject: 190407 Music Performance
subject: 190409 Musicology and Ethnomusicology

description: Supplemental Material, sj-pdf-1-mns-10.1177_20592043211012396 for The Perception of Musical Expression in the Nineteenth Century: The Case of the Glorifying Hymnic* by Frank Hentschel and Gunter Kreutz in Music & Science
Social Determinants of Swimming Ability among Children and Adolescents in Germany. Results of KiGGS Wave 1
Creators: name: Kuntz, Benjamin
name: Frank, Laura
name: Manz, Kristin
name: Rommel, Alexander
name: Lampert, Thomas
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2016
Subjects: subject: Swimming Ability
subject: Drowning
subject: Socioeconomic Status
subject: Migration Background
subject: Health Inequalities
subject: 610 Medizin

description: Background: Swimming is a leisure activity with great potential for promoting health and development. This article examines the proportion of children and adolescents in Germany who are unable to swim, taking into account age, gender, socioeconomic status (SES) and migration background. Methods: Data were obtained from the first follow-up of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS Wave 1), conducted by the Robert Koch Institute (RKI) from 2009 to 2012. Information regarding the swimming ability of 5- to 17-year-olds (n=9,750) was collected by telephone interviews. The SES index is a composite measure of parents‘ education, occupational status and income. Migration background refers to country of birth and nationality of both parents and child. Results: In total, 14.5% of 5- to 17-year-olds in Germany were unable to swim. At pre- and elementary school age, prevalence was considerably higher, in adolescence much lower. Those who were able to swim acquired the ability at just over 6 years of age on average. Among children of primary school age, fewer boys than girls could swim. Girls also learned to swim 4 months earlier on average. Children and adolescents from low-SES families were more likely to be unable to swim than their peers with a high SES (OR=5.95; 95% CI=3.74-9.47). A two-sided migration background (both parents, or the child and one parent, immigrated) was also associated with an elevated odds of being unable to swim (OR=2.39; 95% CI=1.63-3.50). Conclusions: The KiGGS data show that a substantial proportion of children and adolescents in Germany are unable to swim. Initiatives promoting swimming ability should focus on socially disadvantaged children and adolescents and those with a two-sided migration background.
Target Types and Placement for Terrestrial and Mobile Mapping
Creators: name: Peterson, Scott M.
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Civil engineering not elsewhere classified

description: The use of digital three-dimensional (3D) data has increased over the last two decades as private and public firms have begun to realize its utility. Mobile Terrestrial Laser Scanning (MTLS) or Mobile Mapping Systems (MMS), which utilizes LiDAR (Light Detection and Ranging) data collection from a moving platform along with advances in positioning systems—e.g., Global Navigation Satellite Systems (GNSS), Inertial Navigation Systems (INS), and Distance Measurement Instruments (DMIs)—have paved the way for efficient, abundant, and accurate 3D data collection. Validation and control targets are vital to ensure relative and/or absolute accuracy for MTLS projects. The focus of this dissertation is to evaluate several types of targets and the positional spacing of said targets for MTLS.
A mostly planar two-dimensional (2D) targeting system (painted target on ground) is commonly used to constrain, register, and validate the 3D point clouds from MTLS. In this dissertation, 3D objects—a sphere and a cube—were evaluated with varied angles of incidence and point densities as more appropriate alternatives to constrain and validate the 3D MTLS point clouds. Next, a planar circular 2D target—with the use of the raw intensity of the LiDAR pulse as another measured dimension—was evaluated as a proof of concept to also constrain and validate 3D LiDAR data. A third and final component of this dissertation explored analyses of INS data to determine the positional spacing of control and validation targets in MTLS projects to provide maximum accuracy for all data points.
Additional file 1 of Using experience-based co-design to develop mobile/tablet applications to support a person-centred and empowering stroke rehabilitation
Creators: name: Marwaa, Mille Nabsen
name: Guidetti, Susanne
name: Ytterberg, Charlotte
name: Kristensen, Hanne Kaae
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 1. The GRIPP2 reporting checklist on patient and public involvement in research.
Specific Metabolic Markers Are Associated with Future Waist-Gaining Phenotype in Women
Creators: name: Merz, Benedikt
name: Nöthlings, Ute
name: Wahl, Simone
name: Haftenberger, Marjolein
name: Schienkiewitz, Anja
name: Adamski, Jerzy
name: Suhre, Karsten
name: Wang-Sattler, Rui
name: Grallert, Harald
name: Thorand, Barbara
name: Pischon, Tobias
name: Bachlechner, Ursula
name: Floegel, Anna
name: Peters, Annette
name: Boeing, Heiner
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2016
Subjects: subject: 610 Medizin

description: Objective: Our study aims to identify metabolic markers associated with either a gain in abdominal (measured by waist circumference) or peripheral (measured by hip circumference) body fat mass. Methods: Data of 4 126 weight-gaining adults (18–75 years) from three population-based, prospective German cohort studies (EPIC, KORA, DEGS) were analysed regarding a waist-gaining (WG) or hip-gaining phenotype (HG). The phenotypes were obtained by calculating the differences of annual changes in waist minus hip circumference. The difference was displayed for all cohorts. The highest 10% of this difference were defined as WG whereas the lowest 10% were defined as HG. A total of 121 concordant metabolite measurements were conducted using Biocrates AbsoluteIDQ® kits in EPIC and KORA. Sex-specific associations with metabolite concentration as independent and phenotype as the dependent variable adjusted for confounders were calculated. The Benjamini-Hochberg method was used to correct for multiple testing. Results: Across studies both sexes gained on average more waist than hip circumference. We could identify 12 metabolites as being associated with the WG (n = 8) or HG (n = 4) in men, but none were significant after correction for multiple testing; 45 metabolites were associated with the WG (n = 41) or HG (n = 4) in women. For WG, n = 21 metabolites remained significant after correction for multiple testing. Respective odds ratios (OR) ranged from 0.66 to 0.73 for tryptophan, the diacyl-phosphatidylcholines (PC) C32:3, C36:0, C38:0, C38:1, C42:2, C42:5, the acyl-alkyl-PCs C32:2, C34:0, C36:0, C36:1, C36:2, C38:0, C38:2, C40:1, C40:2, C40:5, C40:6, 42:2, C42:3 and lyso-PC C17:0. Conclusion: Both weight-gaining men and women showed a clear tendency to gain more abdominal than peripheral fat. Gain of abdominal fat seems to be related to an initial metabolic state reflected by low concentrations of specific metabolites, at least in women. Thus, higher levels of specific PCs may play a protective role in gaining waist circumference.
Evaluation of the immunogenicity and safety of different doses and formulations of a broad spectrum influenza vaccine (FLU-v) developed by SEEK: study protocol for a single-center, randomized, double-blind and placebo-controlled clinical phase IIb trial
Creators: name: Doorn, Eva Van
name: Pleguezuelos, Olga
name: Liu, Heng
name: Fernandez, Ana
name: Bannister, Robin
name: Stoloff, Gregory
name: Oftung, Fredrik
name: Norley, Stephen
name: Huckriede, Anke
name: Frijlink, Henderik W.
name: Hak, Eelko
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2017
Subjects: subject: Influenza
subject: Vaccine
subject: Broadly protection
subject: Clinical trial
subject: CMI
subject: FLU-v
subject: Universal
subject: 610 Medizin

description: Background: Current influenza vaccines, based on antibodies against surface antigens, are unable to provide protection against newly emerging virus strains which differ from the vaccine strains. Therefore the population has to be re-vaccinated annually. It is thus important to develop vaccines which induce protective immunity to a broad spectrum of influenza viruses. This trial is designed to evaluate the immunogenicity and safety of FLU-v, a vaccine composed of four synthetic peptides with conserved epitopes from influenza A and B strains expected to elicit both cell mediated immunity (CMI) and humoral immunity providing protection against a broad spectrum of influenza viruses. Methods: In a single-center, randomized, double-blind and placebo-controlled phase IIb trial, 222 healthy volunteers aged 18–60 years will be randomized (2:2:1:1) to receive two injections of a suspension of 500 μg FLU-v in saline (arm 1), one dose of emulsified 500 μg FLU-v in Montanide ISA-51 and water for injection (WFI) followed by one saline dose (arm 2), two saline doses (arm 3), or one dose of Montanide ISA-51 and WFI emulsion followed by one saline dose (arm 4). All injections will be given subcutaneously. Primary endpoints are safety and FLU-v induced CMI, evaluated by cytokine production by antigen specific T cell populations (flow-cytometry and ELISA). Secondary outcomes are measurements of antibody responses (ELISA and multiplex), whereas exploratory outcomes include clinical efficacy and additional CMI assays (ELISpot) to show cross-reactivity. Discussion: Broadly protective influenza vaccines able to provide protection against multiple strains of influenza are urgently needed. FLU-v is a promising vaccine which has shown to trigger the cell-mediated immune response. The dosages and formulations tested in this current trial are also estimated to induce antibody response. Therefore, both cellular and humoral immune responses will be evaluated. Trial registration: EudraCT number 2015–001932-38; retrospectively registered clinicaltrials.gov NCT02962908 (November 7th 2016).
Additional file 1 of Molecular characteristics and pathogenicity of infectious cDNA clones of the Chinese isolates of pea enation mosaic virus 1 and pea enation mosaic virus 2
Creators: name: Chen, Xiaojiao
name: Xie, Min
name: Chen, Honglin
name: Zhang, Yue
name: Li, Kehua
name: Lan, Pingxiu
name: Wei, Taiyun
name: Li, Fan
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Additional file1: Table S1. Primers used for detection and amplification of PEMV-1 and PEMV-2. Table S2. Percent nucleotide (nt) identity among three amplicons (each of 801 bp and 483 bp) of four sampling sites. Table S3. Percent nucleotide (nt) and deduced amino acid (aa) identity of ORF3 and ORF5 of PEMV-1-YDL. Comparison of PEMV-1-YDL and known PEMV-1 isolates.
EFFECT OF INTERFACE CHEMICAL COMPOSITION ON THE HIGH STRAIN RATE DEPENDENT MECHANICAL BEHAVIOR OF AN ENERGETIC MATERIAL
Creators: name: Prakash, Chandra
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Aerospace engineering not elsewhere classified
Aerospace materials
Aerospace structures

description: A combined experimental and computational study has been performed in order to understand the effect of interface chemical composition on the shock induced mechanical behavior of an energetic material (EM) system consisting of Hydroxyl-Terminated Polybutadiene (HTPB) binder and an oxidizer, Ammonium Perchlorate (AP), particle embedded in the binder. The current study focuses on the effect of interface chemical composition between the HTPB binder material and the AP particles on the high strain rate mechanical behavior. The HTPB-AP interface chemical composition was changed by adding cyanoethylated polyamine (HX-878 or Tepanol) as a binding agent. A power law viscoplastic constitutive model was fitted to nanoscale impact based experimental stress-strain-strain rate data in order to obtain the constitutive behavior of the HTPBAP interfaces, AP particle, and HTPB binder matrix. An in-situ mechanical Raman spectroscopy framework was used to analyze the effect of binding agent on cohesive separation properties of the HTPB-AP interfaces, AP particle, and HTPB binder matrix. In addition, a combined mechanical Raman spectroscopy and laser impact set up was used to study the effect of strain rate, as well as the interface chemical composition on the interface shock viscosity. Finally, high velocity strain rate impact simulations were performed using an explicit cohesive finite element method framework to predict the effect of strain rate, interface strength, interface friction, and interface shock viscosity on possible strain rate dependent temperature rises at high strain rates approaching shock velocities.
A modified stress equation was used in the cohesive finite element framework in order to include the effect of shock viscosity on the shock wave rise time and shock pressure during impact loading with strain rates corresponding to shock impact velocities. It is shown that increasing the interface shock viscosity, which can be altered by changing the interface chemical composition, increases the shock wave rise time at the analyzed interfaces. It is shown that the interface shock viscosity also plays an important role in determining the temperature increase within the microstructure. Interface shock viscosity leads to a decrease in the overall density of the possible hot-spots which is caused by the increase in dissipation at the shock front. This increase in shock dissipation is accompanied by a decrease in the both the maximum temperature, as well as the plastic dissipation energy, within the microstructure during shock loading.
Additional file 1 of Patient safety topics, especially the second victim phenomenon, are neglected in undergraduate medical and nursing curricula in Europe: an online observational study
Creators: name: Sánchez-García, Alicia
name: Saurín-Morán, Pedro José
name: Carrillo, Irene
name: Tella, Susanna
name: Põlluste, Kaja
name: Srulovici, Einav
name: Buttigieg, Sandra C
name: Mira, José Joaquín
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Science Policy
Mental Health

description: Supplementary Material 1
Additional file 2 of Molecular characteristics and pathogenicity of infectious cDNA clones of the Chinese isolates of pea enation mosaic virus 1 and pea enation mosaic virus 2
Creators: name: Chen, Xiaojiao
name: Xie, Min
name: Chen, Honglin
name: Zhang, Yue
name: Li, Kehua
name: Lan, Pingxiu
name: Wei, Taiyun
name: Li, Fan
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Additional file2: Figure S1. Plant phenotypes and PEMV detection after agro-infiltration of PEMV-1-YDL and PEMV-2-YDL, either singly or in various combinations, on Nicotiana benthamiana plants. Figure S2. The alignment of CP (a) and RTP (b) amino acid sequences of PEMV-1-YDL and PEMV-1-AT+.
Changing educational inequalities in sporting inactivity among adults in Germany: a trend study from 2003 to 2012
Creators: name: Hoebel, Jens
name: Finger, Jonas
name: Kuntz, Benjamin
name: Kroll, Lars Eric
name: Manz, Kristin
name: Lange, Cornelia
name: Lampert, Thomas
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: Sports
subject: Health inequalities
subject: Physical activity
subject: Exercise
subject: Social determinants of health
subject: Physical inactivity
subject: Sports participation
subject: Socioeconomic inequalities in health
subject: 610 Medizin

description: Background: Social inequalities in health can be explained in part by the social patterning of leisure-time physical activity, such as non-participation in sports. This study is the first to explore whether absolute and relative educational inequalities in sporting inactivity among adults have changed in Germany since the early 2000s. Methods: Data from four cross-sectional national health surveys conducted in 2003 (n = 6890), 2009 (n = 16,418), 2010 (n = 17,145) and 2012 (n = 13,744) were analysed. The study population was aged 25–69 years in each survey. Sporting inactivity was defined as no sports participation during the preceding 3 months. The regression-based Slope Index of Inequality (SII) and Relative Index of Inequality (RII) were calculated to estimate the extent of absolute and relative educational inequalities in sporting inactivity, respectively. Results: Sporting inactivity was consistently more prevalent in less-educated groups. The overall prevalence of sporting inactivity declined significantly over time. However, the decline was observed only in the high and medium education groups, while no change was observed in the low education group. Both absolute and relative educational inequalities in sporting inactivity were found to have widened significantly between 2003 (SII = 0.30, 95% CI = 0.25–0.35; RII = 2.08, 95% CI = 1.83–2.38) and 2012 (SII = 0.41, 95% CI = 0.37–0.45; RII = 3.44, 95% CI = 3.03–3.91). Interaction analysis showed that these increases in inequalities were larger in the younger population under the age of 50 than among the elderly. Conclusions: The findings suggest that the gap in sports participation between adults with high and low educational attainment has widened in both absolute and relative terms because of an increase in sports participation among the better educated. Health-enhancing physical activity interventions specifically targeted to less-educated younger adults are needed to prevent future increases in social inequalities in health.
sj-pdf-1-crx-10.1177_00936502211025907 – Supplemental material for Staying Tuned or Tuning Out? A Longitudinal Analysis of News-Avoiders on the Micro and Macro-Level
Creators: name: Gorski, Lea C.
name: Thomas, Fabian
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, sj-pdf-1-crx-10.1177_00936502211025907 for Staying Tuned or Tuning Out? A Longitudinal Analysis of News-Avoiders on the Micro and Macro-Level by Lea C. Gorski and Fabian Thomas in Communication Research
The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges
Creators: name: Gourlay, Annabelle
name: Noori, Teymur
name: Pharris, Anastasia
name: Axelsson, Maria
name: Costagliola, Dominique
name: Cowan, Susan
name: Croxford, Sara
name: Monforte, Antonella D’Arminio
name: Amo, Julia Del
name: Delpech, Valerie
name: Díaz, Asunción
name: Girardi, Enrico
name: Gunsenheimer-Bartmeyer, Barbara
name: Hernando, Victoria
name: Jose, Sophie
name: Leierer, Gisela
name: Nikolopoulos, Georgios
name: Obel, Niels
name: Coul, Eline Op De
name: Paraskeva, Dimitra
name: Reiss, Peter
name: Sabin, Caroline
name: Sasse, André
name: Schmid, Daniela
name: Sonnerborg, Anders
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2017
Subjects: subject: surveillance
subject: HIV infection
subject: antiretroviral therapy.
subject: cohort analysis
subject: continuum of care
subject: 610 Medizin

description: Background: The Joint United Nations Programme on HIV/AIDS (UNAIDS) has set a "90-90-90" target to curb the human immunodeficiency virus (HIV) epidemic by 2020, but methods used to assess whether countries have reached this target are not standardized, hindering comparisons. Methods: Through a collaboration formed by the European Centre for Disease Prevention and Control (ECDC) with European HIV cohorts and surveillance agencies, we constructed a standardized, 4-stage continuum of HIV care for 11 European Union countries for 2013. Stages were defined as (1) number of people living with HIV in the country by end of 2013; (2) proportion of stage 1 ever diagnosed; (3) proportion of stage 2 that ever initiated ART; and (4) proportion of stage 3 who became virally suppressed (≤200 copies/mL). Case surveillance data were used primarily to derive stages 1 (using back-calculation models) and 2, and cohort data for stages 3 and 4. Results: In 2013, 674500 people in the 11 countries were estimated to be living with HIV, ranging from 5500 to 153400 in each country. Overall HIV prevalence was 0.22% (range, 0.09%-0.36%). Overall proportions of each previous stage were 84% diagnosed, 84% on ART, and 85% virally suppressed (60% of people living with HIV). Two countries achieved ≥90% for all stages, and more than half had reached ≥90% for at least 1 stage. Conclusions: European Union countries are nearing the 90-90-90 target. Reducing the proportion undiagnosed remains the greatest barrier to achieving this target, suggesting that further efforts are needed to improve HIV testing rates. Standardizing methods to derive comparable continuums of care remains a challenge.
sj-pdf-1-chl-10.1177_17475198211026506 – Supplemental material for A base-free Chan–Lam reaction catalyzed by an easily assembled Cu(II)-carboxylate metal-organic framework
Creators: name: Zhang, Xinhai
name: Qin, Jianhua
name: Ma, Ruixuan
name: Shi, Lei
Publisher: name: SAGE Journals
Year: 2021
Subjects: Materials Engineering not elsewhere classified

description: Supplemental material, sj-pdf-1-chl-10.1177_17475198211026506 for A base-free Chan–Lam reaction catalyzed by an easily assembled Cu(II)-carboxylate metal-organic framework by Xinhai Zhang, Jianhua Qin, Ruixuan Ma and Lei Shi in Journal of Chemical Research