cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Testing the Testers: Are Young Men Who Have Sex With Men Receiving Adequate HIV Testing and Counseling Services?
Creators: name: Hernandez, Rogelio
name: Sullivan, Patrick S.
name: Dowshen, Nadia
name: Claude, Kristina F.
name: Vickroy, William J.
name: Tanney, Mary
name: Santiago, Dalisa L.
name: Paul, Mary E.
name: Leung, Kingsley
name: Stephenson, Rob
name: Lee, Sonia
name: Lin, Willey Y.
name: Castillo, Marn©
name: Desir, Kimberly
name: Golinkoff, Jesse M.
name: Lopez, Alexander V.
name: Bauermeister, Jose A.
name: Wimbly, Taylor A.
name: Horvath, Keith J.
name: Hightow-Weidman, Lisa
name: Schlupp, Anderson
Publisher: name: Wolters Kluwer
Year: 2019

description: BACKGROUND: The United States Centers for Disease Control and Prevention promote HIV testing every 6 months among young men who have sex with men (YMSM) to facilitate entry into the HIV prevention and care continuum. Willingness to be tested may be influenced by testing services' quality. Using a novel mystery shopper methodology, we assessed YMSM's testing experiences in 3 cities and recommend service delivery improvements. METHODS: We assessed YMSM's experiences at HIV testing sites in Philadelphia (n = 30), Atlanta (n = 17), and Houston (n = 19). YMSM (18-24) were trained as mystery shoppers and each site was visited twice. After each visit, shoppers completed a quality assurance survey to evaluate their experience. Data were pooled across sites, normed as percentages, and compared across cities. RESULTS: Across cites, visits averaged 30 minutes (SD = 25.5) and were perceived as welcoming and friendly (70.9%). YMSM perceived most sites respected their privacy and confidentiality (84.3%). YMSM noted deficiencies in providers' competencies with sexual minorities (63.4%) and comfort during the visit (65.7%). Sites underperformed on Lesbian, Gay, Bisexual, Transgender visibility (49.6%) and medical forms inclusivity (57.95%). Sites on average did not discuss YMSM's relationship context (49.8%) nor provide risk reduction counseling (56.8%) or safer sex education (24.3%). Sites delivered pre-exposure prophylaxis information and counseling inconsistently (58.8%). CONCLUSIONS: Testing sites' variable performance underscores the importance of improving HIV testing services for YMSM. Strategies are recommended for testing sites to promote cultural sensitivity: funding staff trainings, creating systems to assess adherence to testing guidelines and best practices, and implementing new service delivery models.
Bayesian inversion with a hierarchical tensor representation
Creators: name: Eigel, Martin
name: Marschall, Manuel
name: Schneider, Reinhold
Publisher: name: Weierstrass Institute
Year: 2016
Subjects: subject: partial differential equations with random coefficients
subject: tensor representation
subject: tensor train
subject: uncertainty quantification
subject: stochastic finite element methods
subject: operator equations
subject: adaptive methods
subject: low-rank
subject: 35R60
subject: 47B80
subject: 60H35
subject: 65C20
subject: 65N12
subject: 65N22
subject: 65J10

description: The statistical Bayesian approach is a natural setting to resolve the ill-posedness of inverse problems by assigning probability densities to the considered calibration parameters. Based on a parametric deterministic representation of the forward model, a sampling-free approach to Bayesian inversion with an explicit representation of the parameter densities is developed. The approximation of the involved randomness inevitably leads to several high dimensional expressions, which are often tackled with classical sampling methods such as MCMC. To speed up these methods, the use of a surrogate model is beneficial since it allows for faster evaluation with respect to calibration parameters. However, the inherently slow convergence can not be remedied by this. As an alternative, a complete functional treatment of the inverse problem is feasible as demonstrated in this work, with functional representations of the parametric forward solution as well as the probability densities of the calibration parameters, determined by Bayesian inversion. The proposed sampling-free approach is discussed in the context of hierarchical tensor representations, which are employed for the adaptive evaluation of a random PDE (the forward problem) in generalized chaos polynomials and the subsequent high-dimensional quadrature of the log-likelihood. This modern compression technique alleviates the curse of dimensionality by hierarchical subspace approximations of the involved low rank (solution) manifolds. All required computations can be carried out efficiently in the low-rank format. A priori convergence is examined, considering all approximations that occur in the method. Numerical experiments demonstrate the performance and verify the theoretical results.
The Association between Use of Online Social Networks to Find Sex Partners and Sexually Transmitted Infection Diagnosis among Young Men Who Have Sex with Men and Transgender Women Living with HIV
Creators: name: Neilands, Torsten B.
name: Hightow-Weidman, Lisa
name: Hosek, Sybil G.
name: Saberi, Parya
name: Lally, Michelle A.
Publisher: name: SAGE Publications
Year: 2019

description: We conducted a cross-sectional analysis of baseline data from the Adolescent Trials Network for HIV/AIDS Interventions to examine the association between the use of social media sites to find sex partners and recent diagnosis of sexually transmitted infections (STIs) among 13- to 24-year-old men who have sex with men and transgender women living with HIV. We used linear regression to determine the relationship between the number of STIs and the number of social media sites used to find sex partners with each type of sex act included in the analysis. Secondary analyses substituted frequency of social media site use for number of social media sites. Among 741 participants, for every 1 social media account used to find sex partners, there was a 2.53% (95% confidence interval: 0.28-5.54) increase in STIs. This association was mediated through condomless receptive anal intercourse or condomless insertive anal intercourse but not barrierless oral intercourse. Similar but attenuated associations were found when frequency of social media site use was substituted for number of social media sites. Future research should examine innovative interventions on these social media sites with respect for its users.
Ultraviolet Fluorescence Images of Modules in the Field
Creators: name: Gabor, Andrew
name: Danvers Johnston
name: Akissi Yao
name: French, Roger H.
name: Li, Mengjie
name: Yu, Xuanji
name: Michael, Peter
name: Colvin, Dylan J.
name: Bruckman, Laura
name: Oltjen, Will
name: Davis, Kristopher O.
Publisher: name: OSF
Year: 2023

description: This dataset features UV fluorescence images of 7,190 photovoltaic modules of 26 unique make-model combinations installed in the states of Florida, Ohio, and Massachusetts. Modules in Florida were imaged by the Florida Solar Energy Center (FSEC) of the University of Central Florida (UCF); those in Ohio were imaged by Case Western Reserve University (CWRU) and BrightSpot Automation; those imaged in Massachusetts were imaged by BrightSpot Automation. Most of the modules with UVF images in Florida have corresponding IR images in https://osf.io/7v5zt/.

For more data on the SHELL system, visit here: https://osf.io/csr6t/

This material is based upon work supported by the U.S. Department of Energy’s Office of Energy Efficiency and Renewable Energy (EERE) under the Solar Energy Technologies Office Award Number DE-EE0009347.
The Cell Cycle Browser: An Interactive Tool for Visualizing, Simulating, and Perturbing Cell-Cycle Progression
Creators: name: Haggerty, Rachel A.
name: Kedziora, Katarzyna M.
name: Kumar, Jayashree
name: Grant, Gavin D.
name: Purvis, Jeremy E.
name: Wolff, Samuel C.
name: Borland, David
name: Chao, Hui Xiao
name: Cook, Jeanette G.
name: Yi, Hong
Publisher: name: Elsevier
Year: 2018

description: The cell cycle is driven by precise temporal coordination among many molecular activities. To understand and explore this process, we developed the Cell Cycle Browser (CCB), an interactive web interface based on real-time reporter data collected in proliferating human cells. This tool facilitates visualizing, organizing, simulating, and predicting the outcomes of perturbing cell-cycle parameters. Time-series traces from individual cells can be combined to build a multi-layered timeline of molecular activities. Users can simulate the cell cycle using computational models that capture the dynamics of molecular activities and phase transitions. By adjusting individual expression levels and strengths of molecular relationships, users can predict effects on the cell cycle. Virtual assays, such as growth curves and flow cytometry, provide familiar outputs to compare cell-cycle behaviors for data and simulations. The CCB serves to unify our understanding of cell-cycle dynamics and provides a platform for generating hypotheses through virtual experiments.
Implementation and evaluation of a simulation-based educational intervention with first year nursing students in Saudia Arabia: Mixed methods research.
Creators: name: Almutairi, Ashwaq Amer R
Publisher: name: Monash University
Year: 2025
Subjects: classificationCode: 390110
subject: Medicine, nursing and health curriculum and pedagogy

description: The research study investigated the impact of a simulation-based learning program on first-year nursing students' ability to understand and appreciate different cultures in Saudi Arabia. The researchers used a combination of quantitative and qualitative methods to collect and analyse data from a group of first-year nursing students.
The study found that the simulation-based intervention was effective in improving the students' cultural empathy. The students who participated in the program reported increased understanding of different cultural perspectives and improved communication skills.
The research suggested that simulation-based learning can be a valuable tool for developing cultural empathy in nursing students within the Saudi Arabian curriculum. This is essential for providing culturally competent care to patients from diverse backgrounds.
Supplement_Material – Supplemental material for Competence and Satisfaction in Occupational Performance Among a Sample of University Students: An Exploratory Study
Creators: name: Keptner, Karen M.
name: Rogers, Rachel
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences

description: Supplemental material, Supplement_Material for Competence and Satisfaction in Occupational Performance Among a Sample of University Students: An Exploratory Study by Karen M. Keptner and Rachel Rogers in OTJR: Occupation, Participation and Health
The consequences of differential origin licensing dynamics in distinct chromatin environments
Creators: name: Purvis, Jeremy E
name: Kedziora, Katarzyna M
name: Cook, Jeanette Gowen
name: Song, Eun-Ah
name: Mei, Liu
Publisher: name: Oxford University Press (OUP)
Year: 2022

description: Eukaryotic chromosomes contain regions of varying accessibility, yet DNA replication factors must access all regions. The first replication step is loading MCM complexes to license replication origins during the G1 cell cycle phase. It is not yet known how mammalian MCM complexes are adequately distributed to both accessible euchromatin regions and less accessible heterochromatin regions. To address this question, we combined time-lapse live-cell imaging with immunofluorescence imaging of single human cells to quantify the relative rates of MCM loading in euchromatin and heterochromatin throughout G1. We report here that MCM loading in euchromatin is faster than that in heterochromatin in early G1, but surprisingly, heterochromatin loading accelerates relative to euchromatin loading in middle and late G1. This differential acceleration allows both chromatin types to begin S phase with similar concentrations of loaded MCM. The different loading dynamics require ORCA-dependent differences in origin recognition complex distribution. A consequence of heterochromatin licensing dynamics is that cells experiencing a truncated G1 phase from premature cyclin E expression enter S phase with underlicensed heterochromatin, and DNA damage accumulates preferentially in heterochromatin in the subsequent S/G2 phase. Thus, G1 length is critical for sufficient MCM loading, particularly in heterochromatin, to ensure complete genome duplication and to maintain genome stability.
1329_Section_0_Supplementary_Appendix_A_19Jul18 – Supplemental material for Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document
Creators: name: Gooderham, Melinda J.
name: Chih-Ho Hong
name: Albrecht, Lorne
name: Bissonnette, Robert
name: Gurbir Dhadwal
name: Gniadecki, Robert
name: Parbeer Grewal
name: Kirchhof, Mark G.
name: Landells, Ian
name: Lansang, Perla
name: Lynde, Chuck W.
name: Papp, Kim A.
name: Poulin, Yves
name: Sussman, Gordon
name: Turchin, Irina
name: Wiseman, Marni
name: Jensen Yeung
Publisher: name: SAGE Journals
Year: 2018
Subjects: Medicine

description: Supplemental material, 1329_Section_0_Supplementary_Appendix_A_19Jul18 for Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document by Melinda J. Gooderham, Chih-ho Hong, Lorne Albrecht, Robert Bissonnette, Gurbir Dhadwal, Robert Gniadecki, Parbeer Grewal, Mark G. Kirchhof, Ian Landells, Perla Lansang, Chuck W. Lynde, Kim A. Papp, Yves Poulin, Gordon Sussman, Irina Turchin, Marni Wiseman and Jensen Yeung in Journal of Cutaneous Medicine and Surgery
BSM at future linear $e^{+}e^-$ colliders - an experimentalists view
Creators: name: Berggren, Carl Mikael
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2016

description: CLIC workshop 2016, Geneva, CERN, Switzerland, 18 Jan 2016 - 22 Jan 2016 ; (2016).
1329_Section_V_Supplementary_Table_1 – Supplemental material for Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document. Section V: Consensus Statements on the Assessment and Management of Adult Patients With Moderate-to-Severe Atopic Dermatitis
Creators: name: Chih-Ho Hong
name: Gooderham, Melinda J.
name: Albrecht, Lorne
name: Bissonnette, Robert
name: Gurbir Dhadwal
name: Gniadecki, Robert
name: Parbeer Grewal
name: Kirchhof, Mark G.
name: Landells, Ian
name: Lansang, Perla
name: Lynde, Chuck W.
name: Papp, Kim A.
name: Poulin, Yves
name: Sussman, Gordon
name: Turchin, Irina
name: Wiseman, Marni
name: Jensen Yeung
Publisher: name: SAGE Journals
Year: 2018
Subjects: Medicine

description: Supplemental material, 1329_Section_V_Supplementary_Table_1 for Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document. Section V: Consensus Statements on the Assessment and Management of Adult Patients With Moderate-to-Severe Atopic Dermatitis by Chih-ho Hong, Melinda J. Gooderham, Lorne Albrecht, Robert Bissonnette, Gurbir Dhadwal, Robert Gniadecki, Parbeer Grewal, Mark G. Kirchhof, Ian Landells, Perla Lansang, Chuck W. Lynde, Kim A. Papp, Yves Poulin, Gordon Sussman, Irina Turchin, Marni Wiseman and Jensen Yeung in Journal of Cutaneous Medicine and Surgery
WIMP Search in the Mono-Photon Channel at the International Linear Collider
Creators: name: Habermehl, Moritz
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2016

description: Fruehjahrstagung der Deutschen Physikalischen Gesellschaft, DPG, Hamburg, Germany, 29 Feb 2016 - 4 Mar 2016 ; (2016).
Supplemental material for NAVIGATE I: Randomized, Placebo-Controlled, Double-Blind Trial of the Exhalation Delivery System With Fluticasone for Chronic Rhinosinusitis With Nasal Polyps
Creators: name: Sindwani, Raj
name: Han, Joseph K.
name: Soteres, Daniel F.
name: Messina, John C.
name: Carothers, Jennifer L.
name: Mahmoud, Ramy A.
name: Djupesland, Per G.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental Material for NAVIGATE I: Randomized, Placebo-Controlled, Double-Blind Trial of the Exhalation Delivery System With Fluticasone for Chronic Rhinosinusitis With Nasal Polyps by Raj Sindwani, Joseph K. Han, Daniel F.Soteres, John C.Messina, Jennifer L.Carothers, Ramy A.Mahmoud, Per G.Djupesland in American Journal of Rhinology & Allergy
PB_PARECER_CONSUBSTANCIADO_CEP_2473417 – Supplemental material for Validation of Questionnaire on Violence in Affective Relationships
Creators: name: Melo, Rosana Alves De
name: Fernandes, Flávia Emília Cavalcante Valença
name: Tassitano, Rafael Miranda
name: Randau, Karina Perrelli
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, PB_PARECER_CONSUBSTANCIADO_CEP_2473417 for Validation of Questionnaire on Violence in Affective Relationships by Rosana Alves de Melo, Flávia Emília Cavalcante Valença Fernandes, Rafael Miranda Tassitano and Karina Perrelli Randau in Journal of Interpersonal Violence
The future of digital games for HIV prevention and care
Creators: name: Muessig, Kathryn E.
name: Bauermeister, Jose A.
name: Hightow-Weidman, Lisa B.
name: LeGrand, Sara
name: Fiellin, Lynn E.
Publisher: name: Wolters Kluwer
Year: 2017

description: PURPOSE OF REVIEW: Although there has been a significant increase in mHealth interventions addressing the HIV prevention and care continuum, interventions using game mechanics have been less explored. Digital games are rapidly becoming an important tool for improving health behaviors and supporting the delivery of care and education. The purpose of this review is to provide a historical context for the use of gamification and videogames (including those using virtual reality) used in technology-based HIV interventions and to review new research in the field. RECENT FINDINGS: A review of recently published (1 January 2016-31 March 2017) or presented abstracts (2016) identified a paucity of technology-based interventions that included gamification elements or any terms associated with videogames or gameplay. A larger portfolio of digital gaming interventions is in the pipeline. SUMMARY: Use of digital games that include elements of gamification or consist of standalone videogames or virtual-reality-based games, represent a promising intervention strategy to address the HIV prevention and care continuum, especially among youth. Our review demonstrates that there is significant room for growth in this area in designing, developing, testing and most importantly, implementation and dissemination these novel interventions.
Naturalness and light higgsinos: a powerful reason to build ILC
Creators: name: List, Jenny
name: Baer, Howard
name: Berggren, Carl Mikael
name: Tanabe, Tomohiko
name: Fujii
name: Yan, Jacqueline
name: Lehtinen, Suvi-Leena
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2016

description: 38th International Conference on High Energy Physics, Chicago, USA, 3 Aug 2016 - 10 Aug 2016 ; (2016).
WIMP Searches at the International Linear Collider
Creators: name: Habermehl, Moritz
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2016

description: 28th International Conference on High Energy Phisics, ICHEP, Chicago, USA, 3 Aug 2016 - 10 Aug 2016 ; (2016).
The impact of painful knee osteoarthritis on mortality: a community-based cohort study with over 24 years of follow-up
Creators: name: Callahan, L.F.
name: Schwartz, T.A.
name: Renner, J.B.
name: Jordan, J.M.
name: Cleveland, R.J.
name: Losina, E.
name: Alvarez, C.
Publisher: name: Elsevier
Year: 2018

description: OBJECTIVE: To investigate the impact of knee osteoarthritis (OA) and/or knee pain on excess mortality. METHOD: We analyzed data from 4,182 participants in a community-based prospective cohort study of African American and Caucasian men and women aged ≥45 years. Participants completed knee radiographs and questionnaires at baseline and at up to three follow-ups to determine knee OA (rOA), knee pain and covariate status. Mortality was determined through 2015. We used Cox proportional hazards regression with time-varying covariates (TVC) to estimate hazard ratios (HR) and 95% confidence intervals (CI). Additional analyses stratified by sex, race and age were carried out. RESULTS: Median follow-up time was 14.6 years during which 1822 deaths occurred. Baseline knee radiographic osteoarthritis (rOA) was 27.7%, 38.8% at first follow-up, 52.6% at second follow-up and 61.9% at the third follow-up. Knee rOA with pain and knee pain alone were both associated with a >15% increase in premature all-cause mortality. In analyses stratified by sex, race and age, associations between knee pain, with or without knee rOA, and all-cause death were found among women, Caucasians, those ≤65 years of age, and those with a body mass index (BMI)≥30, with observed increased risks of death between 21% and 65%. We observed similar, somewhat attenuated, results for cardiovascular disease (CVD) deaths. CONCLUSION: In models taking into account variables that change over time, individuals who had knee pain, alone or with knee rOA, had increased mortality. These effects were particularly strong among those obese. Effective interventions to reduce knee pain, particularly those including weight management and prevention of comorbidities, could reduce mortality.
MSJ814113_supplementary_table_2 – Supplemental material for Smelling multiple sclerosis: Different qualities of olfactory function reflect either inflammatory activity or neurodegeneration
Creators: name: Bsteh, Gabriel
name: Berek, Klaus
name: Hegen, Harald
name: Teuchner, Barbara
name: Auer, Michael
name: Wurth, Sebastian
name: Pauli, Franziska Di
name: Deisenhammer, Florian
name: Berger, Thomas
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental material, MSJ814113_supplementary_table_2 for Smelling multiple sclerosis: Different qualities of olfactory function reflect either inflammatory activity or neurodegeneration by Gabriel Bsteh, Klaus Berek, Harald Hegen, Barbara Teuchner, Michael Auer, Sebastian Wurth, Franziska Di Pauli, Florian Deisenhammer and Thomas Berger in Multiple Sclerosis Journal
The Importance of Hip Shape in Predicting Hip Osteoarthritis
Creators: name: Nelson, Amanda E.
Publisher: name: Springer Nature
Year: 2018

description: Purpose of review This narrative review summarizes the evidence relating hip shape and risk of osteoarthritis at the hip, with a focus on the most recent body of work.Recent findingsHip osteoarthritis (OA) is a prevalent and potentially disabling condition with few effective non-surgical treatment options. Risk factors for hip OA appear to differ somewhat from those at other sites. Variations in hip morphology, whether assessed through standard geometric measures or statistical modeling methods, seem to increase hip OA risk and may provide a novel approach to interventions to reduce or prevent OA. Such variations have also led to focused surgical interventions to "correct" abnormal shape, although comparisons with non-surgical management are lacking. Summary There remains a lack of understanding regarding the optimal management, whether surgical, non-surgical, or a combination, for FAI syndrome. Even less is known regarding other potential morphologic variations that may contribute to OA risk. Additionally, many individuals who have shape variations that would seem to increase their risk will never develop hip OA. Questions remain regarding key risk factors for hip OA development, which individuals should be targeted for therapies, whether directed at symptoms, function, or prevention, and which therapies should be studied and offered. Trials are underway to help address some of these questions.
Breast Cancer Detection
Creators: name: Yash Pawaskar, Harshith Poojary, Omkar Shriram, Prof. Bhagyashree Patil
Publisher: name: Zenodo
Year: 2025

description: Breast cancer is among the leading causes of cancer-related deaths among women globally. Earlydetection significantly increases the chances of successful treatment and survival. This study presents adeep learning-based approach using the ResNet50 convolutional neural network (CNN) model for theautomated classification of breast cancer from ultrasound images. The system is deployed as a webapplication to facilitate real-time diagnosis support. Experimental evaluation demonstrates high accuracy,sensitivity, and specificity, indicating the model's effectiveness in differentiating malignant, benign, andnormal breast tissue.
The Influence of Autoregressive Relation Strength and Search Strategy on Directionality Recovery in Group Iterative Multiple Model Estimation
Creators: name: Lane, Stephanie
name: Gates, Kathleen
name: Weigard, Alexander
name: Beltz, Adriene
Publisher: name: American Psychological Association (APA)
Year: 2023

description: Unified structural equation modeling (uSEM) implemented in the group iterative multiple model estimation (GIMME) framework has recently been widely used for characterizing within-person network dynamics of behavioral and functional neuroimaging variables. Previous studies have established that GIMME accurately recovers the presence of relations between variables. However, recovery of relation directionality is less consistent, which is concerning given the importance of directionality estimates for many research questions. There is evidence that strong autoregressive relations may aid directionality recovery and indirect evidence that a novel version of GIMME allowing for multiple solutions could improve recovery when such relations are weak, but it remains unclear how these strategies perform under a range of study conditions. Using comprehensive simulations that varied the strength of autoregressive relations among other factors, this study evaluated the directionality recovery of two GIMME search strategies: (a) estimating autoregressive relations by default in the null model (GIMME-AR) and (b) generating multiple solution paths (GIMME-MS). Both strategies recovered directionality best-and were roughly equivalent in performance-when autoregressive relations were strong (e.g., ß = .60). When they were weak (ß ≤ .10), GIMME-MS displayed an advantage, although overall directionality recovery was modest. Analyses of empirical data in which autoregressive relations were characteristically strong (resting state functional MRI) versus weak (daily diary) mirrored simulation results and confirmed that these strategies can disagree on directionality when autoregressive relations are weak. Findings have important implications for psychological and neuroimaging applications of uSEM/GIMME and suggest specific scenarios in which researchers might or might not be confident in directionality results.
limorhyde_supp – Supplemental material for LimoRhyde: A Flexible Approach for Differential Analysis of Rhythmic Transcriptome Data
Creators: name: Singer, Jordan M.
name: Hughey, Jacob J.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Neuroscience

description: Supplemental material, limorhyde_supp for LimoRhyde: A Flexible Approach for Differential Analysis of Rhythmic Transcriptome Data by Jordan M. Singer and Jacob J. Hughey in Journal of Biological Rhythms
Additional file 1 of The impact of dehydration on short-term postoperative complications in total knee arthroplasty
Creators: name: Lung, Brandon
name: Callan, Kylie
name: McLellan, Maddison
name: Kim, Matthew
name: Yi, Justin
name: McMaster, William
name: Yang, Steven
name: So, David
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Marine Biology

description: Additional file 1: Supplemental Table 1. Complications based on dehydration level.
The persistent and evolving HIV epidemic in American men who have sex with men
Creators: name: Nelson, LaRon
name: Mimiaga, Matthew J
name: Sullivan, Patrick S
name: Beyrer, Chris
name: Mayer, Kenneth H
name: Hightow-Weidman, Lisa
name: Mena, Leandro
name: Reisner, Sari
name: Safren, Steven A
name: Daskalakis, Demetre
Publisher: name: Elsevier
Year: 2021

description: Men who have sex with men (MSM) in the USA were the first population to be identified with AIDS and continue to be at very high risk of HIV acquisition. We did a systematic literature search to identify the factors that explain the reasons for the ongoing epidemic in this population, using a social-ecological perspective. Common features of the HIV epidemic in American MSM include role versatility and biological, individual, and social and structural factors. The high-prevalence networks of some racial and ethnic minority men are further concentrated because of assortative mixing, adverse life experiences (including high rates of incarceration), and avoidant behaviour because of negative interactions with the health-care system. Young MSM have additional risks for HIV because their impulse control is less developed and they are less familiar with serostatus and other risk mitigation discussions. They might benefit from prevention efforts that use digital technologies, which they often use to meet partners and obtain health-related information. Older MSM remain at risk of HIV and are the largest population of US residents with chronic HIV, requiring culturally responsive programmes that address longer-term comorbidities. Transgender MSM are an understudied population, but emerging data suggest that some are at great risk of HIV and require specifically tailored information on HIV prevention. In the current era of pre-exposure prophylaxis and the undetectable equals untransmittable campaign, training of health-care providers to create culturally competent programmes for all MSM is crucial, since the use of antiretrovirals is foundational to optimising HIV care and prevention. Effective control of the HIV epidemic among all American MSM will require scaling up programmes that address their common vulnerabilities, but are sufficiently nuanced to address the specific sociocultural, structural, and behavioural issues of diverse subgroups.
The structure of the human cell cycle
Creators: name: Kedziora, Katarzyna M
name: Purvis, Jeremy E
name: Ranek, Jolene S
name: Zikry, Tarek M
name: Sobon, Holly K
name: Taylor, Sovanny R
name: Stallaert, Wayne
name: Taylor, Colin D
name: Young, Catherine L
name: Cook, Jeanette G
Publisher: name: Elsevier
Year: 2021

description: Understanding the organization of the cell cycle has been a longstanding goal in cell biology. We combined time-lapse microscopy, highly multiplexed single-cell imaging of 48 core cell cycle proteins, and manifold learning to render a visualization of the human cell cycle. This data-driven approach revealed the comprehensive "structure" of the cell cycle: a continuum of molecular states that cells occupy as they transition from one cell division to the next, or as they enter or exit cell cycle arrest. Paradoxically, progression deeper into cell cycle arrest was accompanied by increases in proliferative effectors such as CDKs and cyclins, which can drive cell cycle re-entry by overcoming p21 induction. The structure also revealed the molecular trajectories into senescence and the unique combination of molecular features that define this irreversibly arrested state. This approach will enable the comparison of alternative cell cycles during development, in response to environmental perturbation and in disease. A record of this paper's transparent peer review process is included in the supplemental information.
title: Brachial Plexus
Creators: name: Yang, LJ-S
name: Chung, KC
Publisher: name: Elsevier
Year: 2008
Subjects: subject: Adolescent
subject: Adult
subject: Aged
subject: Brachial Plexus
subject: Cadaver
subject: Humans
subject: Middle Aged
subject: Peripheral Nervous System Diseases
subject: Tomography, X-Ray Computed

description: Computed tomographic (CT) anatomy of the normal brachial plexus was analyzed in 50 patients with nonneurologic disease. Identification of anatomic structures on the CT images was facilitated by comparison with cadaver cross sections. Ten patients with clinical brachial plexopathy were also examined. Of these 10 patients, 7 demonstrated lesions of the brachial plexus. Computed tomographic examination of the brachial plexus is useful in detecting mass lesions of the plexus and may allow earlier diagnosis and specific therapy. Whether CT will be reliable in distinguishing idiopathic brachial plexopathy from the plexopathy associated with pathological lesions awaits further study. © 1982 Raven Press, New York.
Supplemental Material3 - Supplemental material for Availability of secondary prevention services after stroke in Europe: An ESO/SAFE survey of national scientific societies and stroke experts
Creators: name: A Webb
name: MR Heldner
name: D Aguiar De Sousa
name: EC Sandset
name: G Randall
name: Y Bejot
name: B Van Der Worp
name: V Caso
name: U Fischer
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Cardiology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, Supplemental Material3 for Availability of secondary prevention services after stroke in Europe: An ESO/SAFE survey of national scientific societies and stroke experts by A Webb, MR Heldner, D Aguiar de Sousa, EC Sandset, G Randall, Y Bejot, B van der Worp, V Caso, U Fischer and On behalf of the ESO-SAFE Secondary Prevention Survey Steering Group: on behalf of the Queen of Hearts and the RECONNECT consortia in European Stroke Journal
Supplemental Material, Table_S1,_S2_and_Fig_S1,_S2,_S3 - Artificial Light at Night of Different Spectral Compositions Differentially Affects Tumor Growth in Mice: Interaction With Melatonin and Epigenetic Pathways
Creators: name: A. E. Zubidat
name: B. Fares
name: F. Fares
name: A. Haim
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental Material, Table_S1,_S2_and_Fig_S1,_S2,_S3 for Artificial Light at Night of Different Spectral Compositions Differentially Affects Tumor Growth in Mice: Interaction With Melatonin and Epigenetic Pathways by A. E. Zubidat, B. Fares, F. Fares, and A. Haim in Cancer Control
Additional file 1 of Surgeon-modified fenestrated endograft for urgent an aortic arch aneurysm: case report
Creators: name: Gallicchio, Vito
name: Barbarisi, Danilo
name: Condò, Flavia
name: Sciarrillo, Rosaria
name: Flora, Loris
Publisher: name: figshare
Year: 2024
Subjects: Biophysics
Space Science
Medicine
Biotechnology
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 1: Table S1. Characteristics of the patient.
Trajectories of Depressive Symptoms, Neurocognitive Function, and Viral Suppression With Antiretroviral Therapy Among Youth With HIV Over 36 months
Creators: name: Garvie, Patricia A.
name: Kim-Chang, Julie J.
name: Woods, Steven Paul
name: Kohn, Jordan N.
name: Rendina, H. Jonathon
name: Fischer, Bernard
name: Sleasman, John W.
name: Loop, Matthew Shane
name: Hong, Suzi
name: Nichols, Sharon L.
Publisher: name: Wolters Kluwer
Year: 2021

description: BACKGROUND: Depression and neurocognitive impairment are highly prevalent among persons living with HIV and associated with poorer clinical outcomes; however, longitudinal studies of depression-neurocognition relationships in youth living with HIV (YLWH), and the role of antiretroviral therapy (ART), are lacking. This study tested whether (1) depressive symptomatology, across somatic, cognitive, and affective symptom domains, improved with ART and (2) more severe depressive symptoms at baseline were associated with poorer neurocognitive function and poorer HIV suppression. SETTING: Data were collected from 181 YLWH (18-24 years) who were treatment-naive, a subset of whom (n = 116) initiated ART. METHODS: Participants were categorized into elevated (DS) or nonelevated (non-DS) depressive symptom groups at entry (Beck Depression Inventory-II ≥14) and followed for 36 months. Neurocognition (5-domain battery) and depressive symptoms were repeatedly assessed. Longitudinal models examined depressive symptomatology, neurocognition, and odds of HIV nonsuppression by group. RESULTS: Greater improvements in depressive symptoms were observed in the DS group over 36 months [beta = -0.14, (-0.24 to -0.03)], particularly within cognitive and affective domains. Verbal learning performance increased in the DS group [beta = 0.13, (0.01 to 0.24)], whereas psychomotor function improved somewhat in the non-DS group [beta = -0.10, (-0.22 to 0.00)]. Adjusted for ART adherence, odds of HIV nonsuppression did not significantly differ by group [odds ratio = 0.22, (0.04 to 1.23)]; however, greater somatic symptoms at study entry were associated with an increased risk of nonsuppression over time [odds ratio = 2.33 (1.07 to 5.68)]. CONCLUSION: Depressive symptoms were associated with differential neurocognitive trajectories, and somatic depressive symptoms at baseline may predict poorer subsequent HIV suppression. Identifying and treating depressive symptoms at ART initiation may benefit neurocognitive and clinical outcomes in YLWH.
Manipulating free will beliefs using online video games
Creators: name: Tavernier, Nel
name: Wisniewski, David
name: Brass, Marcel
Publisher: name: Humboldt-Universität zu Berlin
Year: 2023
Subjects: subject: 150 Psychologie

description: Research in social psychology and experimental philosophy has investigated lay people’s free will beliefs (FWB). Using different approaches (i.e. experimental manipulations and vignette studies), they investigated how FWB relate to other concepts, and whether changing FWB has an impact on downstream processes such as social behavior. However, both approaches have shortcomings. While experimental manipulations used in social psychology suffer from demand effects, vignettes used in experimental philosophy are often highly abstract. Across two pre-registered studies, we developed a new approach by merging them in an online video game setting. Using this novel, experience-based FWB manipulation, we found that decreasing FWB impacted variables such as perceived control and responsibility in both studies. While the experience-based manipulation influenced participants’ beliefs in free will within the context of the experience (“Within the context of the scenario, would the agent believe in free will?”) in the first study, this manipulation effect did not transfer to participants’ general FWB (“Do you believe in free will?”) in the second study. Overall, our findings suggest a way forward in studying laypeople’s beliefs in free will.
Triggered Escalating Real-Time Adherence Intervention to Promote Rapid HIV Viral Suppression Among Youth Living With HIV Failing Antiretroviral Therapy: Protocol for a Triggered Escalating Real-Time Adherence Intervention
Creators: name: Dallas, Ronald
name: Neilan, Anne
name: Polier, Melissa
name: Gaur, Aditya
name: Hudgens, Michael
name: Amico, K Rivet
name: Ciaranello, Andrea
name: Horvath, Keith
name: Filipowicz, Teresa
name: Flynn, Patricia
name: Lindsey, Jane
name: Hill, Emily
name: Johnson, Megan Mueller
name: Goolsby, Rachel West
name: Dunlap, Amanda
name: Heckman, Barbara
name: Miller, Jessica
name: Lee, Sonia
Publisher: name: JMIR Publications
Year: 2019

description: BACKGROUND: Youth living with HIV (YLWH) are confronted with many self-care challenges that can be experienced as overwhelming in the context of normal developmental processes that characterize adolescence and young adulthood. A sizable minority of YLWH have unsuppressed viral loads in the United States attributable to antiretroviral therapy (ART) nonadherence. Interventions to promote sustained viral suppression in YLWH are needed. OBJECTIVE: The aim of this study is to evaluate the efficacy of the Triggered Escalating Real-Time Adherence (TERA) intervention in comparison with standard of care (SOC) in YLWH (aged 13-24 years) failing ART on (1) primary outcome measures-HIV viral suppression (VLS), defined as both <200 copies/ml and <50 copies/ml at 12 weeks, and (2) secondary outcome measures-VLS rates and rates of ART adherence at 24, 36, and 48 weeks as well as patterns of adherence over time as measured by an electronic dose monitoring (EDM) device. METHODS: The TERA study is a phase 2, multisite clinical trial conducted with 120 YLWH failing ART (randomized 1:1 to TERA or SOC) at participating clinical sites within the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). Participants are followed for a total of 48 weeks. For TERA arm participants, the first 12 weeks involve delivery of the intervention. For all participants, clinical outcomes are collected throughout follow-up, and adherence is assessed using EDM over the full 48 weeks. During the 12-week intervention period, TERA arm participants receive 3 remote coaching sessions delivered in clinic via videoconferencing timed to coincide with baseline and follow-up clinical visits, text message reminders when the EDM has not been opened at dose time (which escalate to 2-way theory-informed short message service coaching interactions in response to real-time nonadherence), and review of dosing graphs produced by EDM at follow-up visits. RESULTS: Launch dates for enrollment varied by site. Enrollment began in April 2018 and is expected to be completed by August 2019, with results presented by the second quarter of 2021. CONCLUSIONS: Effective, generalizable, and scalable approaches to rapidly assist YLWH failing to achieve and sustain VLS may have a substantial impact on individual health and efforts to curb transmission. Coaching for a brief but intensive period from remote coaches and using communication channels common to youth may offer multiple unique advantages in promoting self-care.
Supplemental Material, Supplementary_table_1-revised - Clinical Significance of Polo-Like Kinase 4 as a Marker for Advanced Tumor Stage and Dismal Prognosis in Patients With Surgical Gastric Cancer
Creators: name: Cao, Ting
name: Yi, Shijie
name: Yang, Xuefeng
name: Wu, Qing
Publisher: name: SAGE Journals
Year: 2020
Subjects: Oncology and Carcinogenesis not elsewhere classified
Radiology and Organ Imaging
Biochemistry

description: Supplemental Material, Supplementary_table_1-revised for Clinical Significance of Polo-Like Kinase 4 as a Marker for Advanced Tumor Stage and Dismal Prognosis in Patients With Surgical Gastric Cancer by Ting Cao, Shijie Yi, Xuefeng Yang and Qing Wu in Technology in Cancer Research & Treatment
Unsupervised Classification During Time-Series Model Building
Creators: name: Gates, Kathleen M.
name: Guiskewicz, K.
name: Giovanello, K.
name: Lane, Stephanie T.
name: Varangis, E.
Publisher: name: Taylor & Francis
Year: 2016

description: Researchers who collect multivariate time-series data across individuals must decide whether to model the dynamic processes at the individual level or at the group level. A recent innovation, group iterative multiple model estimation (GIMME), offers one solution to this dichotomy by identifying group-level time-series models in a data-driven manner while also reliably recovering individual-level patterns of dynamic effects. GIMME is unique in that it does not assume homogeneity in processes across individuals in terms of the patterns or weights of temporal effects. However, it can be difficult to make inferences from the nuances in varied individual-level patterns. The present article introduces an algorithm that arrives at subgroups of individuals that have similar dynamic models. Importantly, the researcher does not need to decide the number of subgroups. The final models contain reliable group-, subgroup-, and individual-level patterns that enable generalizable inferences, subgroups of individuals with shared model features, and individual-level patterns and estimates. We show that integrating community detection into the GIMME algorithm improves upon current standards in two important ways: (1) providing reliable classification and (2) increasing the reliability in the recovery of individual-level effects. We demonstrate this method on functional MRI from a sample of former American football players.
Uptake and Acceptability of MyChoices: Results of a Pilot RCT of a Mobile App Designed to Increase HIV Testing and PrEP Uptake Among Young American MSM
Creators: name: Jones, Jeb
name: Futterman, Donna
name: Hightow-Weidman, Lisa
name: Sullivan, Patrick S.
name: Daddario, Salvatore R.
name: Hill-Rorie, Jonathan
name: Mayer, Kenneth H.
name: Mimiaga, Matthew J.
name: Biello, Katie B.
Publisher: name: Springer Nature
Year: 2022

description: Young men who have sex with men (YMSM) remain at disproportionate risk for HIV acquisition in the United States (US), yet use of evidence-based prevention strategies, including routine HIV testing and pre-exposure prophylaxis (PrEP), remain low. Smartphones and mobile app usage are nearly ubiquitous in this population. Given the potential for scalability, a mobile app to increase HIV testing and PrEP use among YMSM has the potential to make an extraordinary public health impact if efficacious. Based on extensive formative, community-engaged research, we developed a theory-driven mobile app-MyChoices-to increase HIV testing and PrEP uptake among YMSM. In a pilot randomized controlled trial (RCT), participants (n=60) were randomized 2:1 to receive MyChoices or standard of care (SOC). Data from 3 to 6-month post-baseline assessments demonstrate that the app was highly acceptable (System Usability Score; mean=75.8, SD=10.7) and feasible (94% used the MyChoices app at least once; mean=15.3 sessions, SD=9.8). While not powered to assess efficacy, those in the MyChoices arm had 22% higher prevalence of HIV testing over follow-up compared to those in the SOC arm (NS). There was no difference in PrEP uptake. A fully-powered efficacy trial is warranted; if efficacy is demonstrated, the MyChoices app could be easily scaled to reach YMSM across the US.
Additional file 1 of Ethnobotanical study of medicinal plants in Asagirt District, Northeastern Ethiopia
Creators: name: Tahir, Muhidin
name: Asnake, Hiwot
name: Beyene, Tadesse
name: Van Damme, Patrick
name: Mohammed, Amin
Publisher: name: figshare
Year: 2024
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 1. List of medicinal plants, habits, part used, condition and ways of preparation, routes of administration, ailment treated and collection number in Asagirt District (CP = Condition of preparation, MA = Method of application, RA = Routes of administration, H = Home garden, W = Wild, F = Fresh, D = Dried, H/L = Human or Livestock, HU = Human, Li = Livestock Fu = Furniture, Fr = Forage, Fo = Food, Sp = Spice, Co = Construction, Or = Ornamental, Fe = Fuel, Si = Soil fertility, So = Social use, Tb = Traditional beverage, Ch = Charcoal, L = Live fence).