cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Volatile and aroma profiling of flower and rhizome of Hedychium flavescens growing in North Western Himalayan region
Creators: name: Kumar, Kushal
name: Malhotra, Jigyasa
name: Joshi, Robin
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology

description: The present investigation was carried out for a comparative volatile study and aroma profiling of Hedychium flavescens. The headspace gas chromatography mass spectrometry (GC-MS) analysis of flowers (HS-F) and rhizome (HS-R); GC-MS analysis of flower essential oil (EO-F), flower absolute (AB-F) and rhizome essential oil (EO-R) revealed 27, 19, 19, 15 and 12 compounds which constitute 96.22%, 96.93% 97.43%, 86.79% and 97.62% composition, respectively. The identification results demonstrated that flowers and rhizome were rich in β-pinene, 1,8-cineol, linalool and E-β-caryohyllene components. β-Pinene was the most abundant component in HS-R (38.99%), EO-R (26.61%); linalool in HF-F (25.34%) and EO-F (25.99%) and ρ-vinyl-guaiacol in AB-F (32.19%), respectively. The aroma profile of H. flavescens was dominated with floral and jasmine (flowers); spicy, earthy and herbal (EO-F); floral and balsamic (AB-F); herbal, pungent, spicy and earthy (rhizome and EO-R) notes. Based on aroma profile, AB-F was evaluated as potential ingredient for perfume industry.
The important role of evolution in the Planck $Y_{SZ}$-mass calibration
Creators: name: Andreon, S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: In light of the tension between cosmological parameters from Planck cosmic microwave background and galaxy clusters, we revised the Planck analysis of the $Y_{SZ}$-mass calibration to allow evolution to be determined by the data instead of being imposed as an external constraint. Our analysis uses the very same data and Malmquist bias corrections as used by the Planck team in order to emphasize that differences in the results come from differences in the assumptions. The evolution derived from 71 calibrating clusters, with $0.05
description: A&A letters, in press. Swapped main and secondary analyses to improve readability. Results unchanged
Characterization of alkaloid profile of Hyoscyamus reticulatus L. and Atropa belladonna subsp. caucasica (Kreyer) Avet by LC-MS and NMR
Creators: name: Valiyeva, Adila
name: Felegyi-Tóth, Csenge Anna
name: Várnai, Bianka
name: Garaev, Eldar
name: Béni, Szabolcs
name: Kursinszki, László
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: The alkaloid profile of Hyoscyamus reticulatus L. and Atropa belladonna subsp. caucasica (Kreyer) Avet have not been characterized yet. UHPLC-PDA-Q-TOF-MS/MS and LC-DAD-QqQ-MS/MS methods were used herein to characterize the metabolite profiles of these plants. Flash chromatography in combination with preparative- and semi preparative HPLC were utilized for the isolation of the compounds of interest. The structure of the isolated compounds was proposed based on their MS/MS fragmentation and NMR characteristics. As a total of 19 tropane derivatives, two tyramine derivatives (N-cis- and N-trans- feruloyl tyramine), a lignanamide (grossamide), an alkylamide (pellitorine) were identified in the root and herb extracts of H. reticulatus. Moreover, rutin and caffeoylquinic acids were found in the leaves and fruits, while kaempferol-3-O-glucoside-7-O-rhamnoside and quercetin-3-O-glucoside-rhamnoside-rhamnoside were exclusively characteristic for the leaves of H. reticulatus. The root and herb extracts of A. caucasica contained 16 tropane alkaloid derivatives along with methyl tropate and two tyramine derivatives.
Lattice Boltzmann Model for The Volume-Averaged Navier-Stokes Equations
Creators: name: Zhang, Jingfeng
name: Wang, Limin
name: Ouyang, Jie
Publisher: name: arXiv
Year: 2014
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: A numerical method, based on the discrete lattice Boltzmann equation, is presented for solving the volume-averaged Navier-Stokes equations. With a modified equilibrium distribution and an additional forcing term, the volume-averaged Navier-Stokes equations can be recovered from the lattice Boltzmann equation in the limit of small Mach number by the Chapman-Enskog analysis and Taylor expansion. Due to its advantages such as explicit solver and inherent parallelism, the method appears to be more competitive with traditional numerical techniques. Numerical simulations show that the proposed model can accurately reproduce both the linear and nonlinear drag effects of porosity in the fluid flow through porous media.
description: 9 pages, 2 figures
Introduction
Creators: name: Franco, Ludovico
Publisher: name: Quaderni di Linguistica e Studi Orientali
Year: 2018

description: It is a great pleasure to introduce readers to this special issue of Quaderni di Linguistica e Studi Orientali (Working Papers in Linguistics and Oriental Studies), focusing on the morpho-syntax of (Romance based) Creole and Mixed languages. The papers in this volume address this issue from a variety of viewpoints. It is our humble hope that we have succeeded in broadly enriching the perspective on language creation, contact and change by speaking across different theoretical frameworks and diff erent sets of data.
description: Quaderni di Linguistica e Studi Orientali, Vol. 4 (2018)
Association of Dietary Protein Consumption With Incident Silent Cerebral Infarcts and Stroke: The Atherosclerosis Risk in Communities (ARIC) Study
Creators: name: Mosley, Thomas H.
name: Misialek, Jeffrey R.
name: Haring, Bernhard
name: Alonso, Alvaro
name: Rebholz, Casey M.
name: Gottesman, Rebecca F.
name: Petruski-Ivleva, Natalia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The effect of dietary protein on the risk of stroke has shown inconsistent results. We aimed to evaluate the relationship of dietary protein sources with the risk of stroke and silent cerebral infarcts in a large community based cohort.
"Kot nou vire tourne nou tand li" Serial Verb Constructions at the Interface between Grammar and Culture: Case-Study Kreol Seselwa (Seychelles Creole)
Creators: name: Adone, Dany
name: Brück, Melanie A.
name: Gabel, Astrid
Publisher: name: Quaderni di Linguistica e Studi Orientali
Year: 2018

description: Th is paper investigates the form and function of Verb Chains and Serial Verb Constructions (SVCs) in Kreol Seselwa (Seychelles Creole, KS), a French-based Creole language spoken in the Indian Ocean. Prior to Bickerton’s seminal paper in 1989, it was widely assumed that Serial Verb Constructions were not part of KS grammar. More recent studies (Adone 2012; Syea 2013a, 2013b; Gabel 2018) have shown that these constructions do exist in Indian Ocean Creoles and in KS. Likewise, in this paper, we will demonstrate that from a typological perspective, prototypical as well as non-prototypical SVCs can be found in KS. In our analysis, we provide evidence that an ethnosyntactic framework can account for certain SVCs in KS. We argue that their form and function can be accounted for by cultural logic hence stressing the link between grammar and culture.
description: Quaderni di Linguistica e Studi Orientali, Vol 4 (2018)
Photonic spin Hall effect in metasurfaces with rotational symmetry-breaking
Creators: name: Liu, Yachao
name: Ling, Xiaohui
name: Yi, Xunong
name: Zhou, Xinxing
name: Chen, Shizhen
name: Ke, Yougang
name: Luo, Hailu
name: Wen, Shuangchun
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Observation of photonic spin Hall effect (SHE) in dielectric-based metasurfaces with rotational symmetry breaking is presented. We find that the spin-dependent splitting is a unique angular splitting in the real position space, and is attributed to the space-variant Pancharatnam-Berry phase (PB). Breaking the rotational symmetry of the PB phase by misalignment of the central axes of the incident beam and the metasurface, the spin-dependent shift is observable. We show that the spin-dependent shift can be enhanced by increasing the rotation rate of the metasurface, so the metasurface provides a great flexibility in the manipulation of photonic SHE.
Composition and seasonal variation of volatile organic compounds in Santolina etrusca (Lacaita) Marchi & D’Amato found at Acquapendente (Viterbo, Central Italy)
Creators: name: D’Auria, Maurizio
name: Bellocchi, Daniele
name: Battellocchi, Giuseppe
name: Monachino, Chiara
name: Guidobaldi, Elena
name: Marucci, Francesca
name: Billi, Luciana
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Physical Sciences not elsewhere classified
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: The main component of the essential oil of Santolina etrusca is viridiflorol (23.98–42.23%). a compound not found in the essential oil of Santolina camaecyparissus. The main component found in this study is the same found in the essential oil obtained from plants collected in Tuscany and Umbria. However, there are important differences in the other components of the essential oil, where we found the presence of eucalyptol (2.98–9.73%) and germacrene D (2.39–19.59%). Finally, seasonal variation of the essential oil composition induces a reduction of sesquiterpenes amounts with the corresponding increase of the monoterpenes during spring and summer.
Volatile organic compounds from Citrus australasica growing in Basilicata (Southern Italy)
Creators: name: D’Auria, Maurizio
name: Racioppi, Rocco
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: Virology

description: SPME-GCMS analysis of vesicles of Sanguinea cultivar showed the presence of limonene (45.63%), sabinene (22.65%), and bicyclogermacrene (10.80%). The analysis of the peel showed that the main components were limonene (48.24%), sabinene (37.15%), and α-pinene (4.26%). In Pink Ice cultivar the main components of the vesicles were sabinene (31.68%), limonene (20.71%), and bicyclogermacrene (14.18%). Peel analysis showed the presence of limonene (37.68%), sabinene (33.33%), and α-pinene (5.55%). In Faustrime limonene (51.54%), γ-terpinene (10.01%), α-bergamotene (7.48%), β-bisabolene (7.07%), and a-phellandrene (5.68%) were detected. In peel analysis limonene (27.84%), α-pinene (9.41%), γ-terpinene (10.00%), and citronellal (10.51%) were found.
VComputeBench: A Vulkan Benchmark Suite for GPGPU on Mobile and Embedded GPUs
Creators: name: Mammeri, Nadjib
name: Juurlink, Ben
Publisher: name: Technische Universität Berlin
Year: 2018
Subjects: subject: 004 Datenverarbeitung; Informatik
subject: VComputeBench
subject: Vulkan
subject: SPIR-V
subject: GPGPU
subject: CUDA
subject: OpenCL
subject: Rodinia
subject: mobile

description: GPUs have become immensely important computational units on embedded and mobile devices. However, GPGPU developers are often not able to exploit the compute power offered by GPUs on these devices mainly due to the lack of support of traditional programming models such as CUDA and OpenCL. The recent introduction of the Vulkan API provides a new programming model that could be explored for GPGPU computing on these devices, as it supports compute and promises to be portable across different architectures. In this paper we propose VComputeBench, a set of benchmarks that help developers understand the differences in performance and portability of Vulkan. We also evaluate the suitability of Vulkan as an emerging cross-platform GPGPU framework by conducting a thorough analysis of its performance compared to CUDA and OpenCL on mobile as well as on desktop platforms. Our experiments show that Vulkan provides better platform support on mobile devices and can be regarded as a good crossplatform GPGPU framework. It offers comparable performance and with some low-level optimizations it can offer average speedups of 1.53x and 1.66x compared to CUDA and OpenCL respectively on desktop platforms and 1.59x average speedup compared to OpenCL on mobile platforms. However, while Vulkan’s low-level control can enhance performance, it requires a significantly higher programming effort.
Supplementary document for Geometric Amplitude Assisted Beamforming in Transverse-Twist Metasurfaces - 7190493.pdf
Creators: name: Tang, Peng
name: Tao, Jie
name: liao, dashuang
name: Yang, Yang
name: Chen, Hongsheng
name: wang, zuojia
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: Supplement document
Defining the Ischemic Penumbra Using Magnetic Resonance Oxygen Metabolic Index
Creators: name: Panagos, P.
name: Khoury, N.
name: An, H.
name: Powers, W. J.
name: Derdeyn, C. P.
name: Shanechi, A. M.
name: Ponisio, R.
name: Ford, A. L.
name: Lin, W.
name: Zhu, H.
name: Vo, K. D.
name: Lee, J.-M.
name: Kumar, G.
name: Williams, J.
name: Chen, Y.
name: Diringer, M. N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Penumbral biomarkers promise to individualize treatment windows in acute ischemic stroke. We used a novel MRI approach which measures oxygen metabolic index (OMI), a parameter closely related to PET-derived cerebral metabolic rate of oxygen utilization, to derive a pair of ischemic thresholds: (1) an irreversible-injury threshold which differentiates ischemic core from penumbra and (2) a reversible-injury threshold which differentiates penumbra from tissue not-at-risk for infarction.
Surface and bulk components of electrical conductivity in the (presumably special topological) Kondo insulator SmB6 at lowest temperatures
Creators: name: Gabani, Slavomir
name: Pristas, Gabriel
name: Takacova, Iveta
name: Sluchanko, Nikolay
name: Siemensmeyer, Konrad
name: Shitsevalova, Natalia
name: Filipov, Volodymyr
name: Flachbart, Karol
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Samarium hexaboride (SmB6) has recently been considered to be a topological Kondo insulator (TKI), the first strongly correlated electron system to exhibit topological surface conduction states. In this contribution, results of electrical resistivity measurements between 80 K and 0.08 K of various SmB6 single crystalline samples are presented, analyzed and discussed. The received results imply that the residual conductivity of SmB6 below about 4 K is of non-activated (metallic-like) nature. It is shown that this metallic-like behavior can be attributed both to surface (2D) conduction states, as may be expected in case of a topological insulator, as well as to the highly correlated many-body (3D) bulk ground state which is formed within the gap of this compound. From this it follows that in SmB6, where surface conductivity states are clearly present, there is in parallel also a bulk contribution to residual electrical conductivity originating from the strongly correlated electron system with valence fluctuations. This raises the question whether SmB6 does not form a new / special type of topological insulator in which in the energy gap besides the surface conduction states, there is also a conducting narrow in-gap band originating from the bulk strongly correlated electron system.
description: 9 pages, 5 figures
Midlife Alcohol Consumption and the Risk of Stroke in the Atherosclerosis Risk in Communities Study
Creators: name: Avery, Christy L.
name: Gottesman, Rebecca F.
name: Rosamond, Wayne D.
name: Shahar, Eyal
name: Loehr, Laura
name: Wruck, Lisa
name: Jones, Sara B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Alcohol consumption is common in the US and may confer beneficial cardiovascular effects at light-to-moderate doses. The alcohol-stroke relationship remains debated. We estimated the relationship between mid-life, self-reported alcohol consumption and ischemic stroke (IS) and intracerebral hemorrhage (ICH) in a biracial cohort.
title: Bridging the gap between science and society: long-term effects of the Healthy Lifestyle Community Programme (HLCP, cohort 1) on weight and the metabolic risk profile: a controlled study
Creators: name: Anand, Corinna
name: Kranz, Ragna-Marie
name: Husain, Sarah
name: Koeder, Christian
name: Schoch, Nora
name: Alzughayyar, Dima-Karam
name: Gellner, Reinhold
name: Hengst, Karin
name: Englert, Heike
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2022
Subjects: subject: 610 Medicine and health

description: Background: The potential of adopting a healthy lifestyle to fight non-communicable diseases (NCDs) is not fully used. We hypothesised that the Healthy Lifestyle Community Programme (HLCP, cohort 1) reduces weight and other risk markers compared with baseline and control. Methods: 24-month, non-randomised, controlled intervention trial. Intervention: intensive 8-week phase with seminars, workshops and coaching focusing on a healthy lifestyle (eg, plant-based diet, physical activity, stress management) and group support followed by a 22-month alumni phase. Weight reduction as the primary outcome and other NCD risk parameters were assessed at six time points. Participants were recruited from the general population. Multiple linear regression analyses were conducted. Results: 143 participants (58±12 years, 71% female) were enrolled (91 in the intervention (IG) and 52 in the control group (CG)). Groups’ baseline characteristics were comparable, except participants of IG were younger, more often females, overweight and reported lower energy intake (kcal/day). Weight significantly decreased in IG at all follow-ups by −1.5 ± 1.9 kg after 8 weeks to −1.9 ± 4.0 kg after 24 months and more than in CG (except after 24 months). Being male, in the IG or overweight at baseline and having a university degree predicted more weight loss. After the intervention, there were more participants in the IG with a ‘high’ adherence (+12%) to plant-based food patterns. The change of other risk parameters was most distinct after 8 weeks and in people at elevated risk. Diabetes-related risk parameters did not improve. Conclusion: The HLCP was able to reduce weight and to improve aspects of the NCD risk profile. Weight loss in the IG was moderate but maintained for 24 months. Participants of lower educational status might benefit from even more practical units. Future interventions should aim to include more participants at higher risk.
description: Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Pandatonkinosides A and B: two new phenolic glycosides from the roots of Pandanus tonkinensis and their nitric oxide production inhibitory activities
Creators: name: Trang, Dinh Thi Huyen
name: Anh, Duong Hong
name: Ngo, Quoc Anh
name: Viet, Pham Hung
name: Tai, Bui Huu
name: Nhiem, Nguyen Xuan
name: Van Kiem, Phan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology

description: Two new phenolic glycosides, 4-(3-hydroxypropyl)-2,6-dimethoxyphenol β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (1), trans-cinnamyl alcohol 9-O-(6′-O-β-D-apiofuranosyl)-β-D-glucopyranoside (2), together with nine known phenolic glycosides (3-11) were isolated from the roots of Pandanus tonkinensis. Their structures were determined by extensive analysis of HRESIMS and NMR spectral data, as well as by comparison of their spectral data (including CD spectra) with those reported in the literature. Compounds 1-4 and 6-11 inhibited NO production in LPS-activated RAW264.7 cells with IC50 values in the range from 0.80 ± 0.06 µM to 43.38 ± 3.92 µM, whereas compound 5 was inactive. The NO production inhibitory activities of compounds 1, 4, 8, and 10 with IC50 values of 10.16 ± 1.05, 0.80 ± 0.06, 1.10 ± 0.13, and 2.79 ± 0.21 µM, respectively, are as potent as that of the positive control of NG-monomethyl-L-arginine acetate (L-NMMA) with an IC50 value of 9.80 ± 0.78 µM.
Chemical variability of volatile concentrate from two Ipomoea L. species within a seasonal gradient
Creators: name: da Silva Júnior, Oseias Souza
name: de Jesus Pereira Franco, Celeste
name: de Moraes, Ângelo Antônio Barbosa
name: Pastore, Mayara
name: Cascaes, Marcia Moraes
name: do Nascimento, Lidiane Diniz
name: de Oliveira, Mozaniel Santana
name: de Aguiar Andrade, Eloisa Helena
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: In the present study, are extracted volatile concentrate from Ipomoea asarifolia Poir. and Ipomoea setifera (Desr.) Roem. & Schult. in five-month seasonal gradient. The flowers were subjected to simultaneous distillation − extraction (SDE). The chemical composition of the volatile concentrate was determined by gas chromatography (CG/MS) and (CG-FID). Principal Component Analysis (PCA) and Hierarchical Clustering Analysis (HCA) were performed with the chemical constituents. It was observed that the chemical composition of I. asarifolia varied more with seasonality in relation to the species I. setifera. Furthermore, there is a possibility that germacrene D and α-copaene, the main components of the variation volatile of I. asarifolia and with higher concentrations in the rainy months, have ecological importance, attracting specific pollinators for the rainy season. This is the first study to report the chemical composition of the volatile compounds of I. asarifolia and I. setifera along a seasonal gradient.
Strong-coupling limit of depleted Kondo- and Anderson-lattice models
Creators: name: Titvinidze, Irakli
name: Schwabe, Andrej
name: Potthoff, Michael
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Fourth-order strong-coupling degenerate perturbation theory is used to derive an effective low-energy Hamiltonian for the Kondo-lattice model with a depleted system of localized spins. In the strong-J limit, completely local Kondo singlets are formed at the spinful sites which bind a fraction of conduction electrons. The low-energy theory describes the scattering of the excess conduction electrons at the Kondo singlets as well as their effective interactions generated by virtual excitations of the singlets. Besides the Hubbard term, already discussed by Nozieres, we find a ferromagnetic Heisenberg interaction, an antiferromagnetic isospin interaction, a correlated hopping and, in more than one dimensions, three- and four-site interactions. The interaction term can be cast into highly symmetric and formally simple spin-only form using the spin of the bonding orbital symmetrically centered around the Kondo singlet. This spin is non-local. We show that, depending on the geometry of the depleted lattice, spatial overlap of the non-local spins around different Kondo singlets may cause ferromagnetic order. This is sustained by a rigorous argument, applicable to the half-filled model, by a variational analysis of the stability of the fully polarized Fermi sea of excess conduction electrons as well as by exact diagonalization of the effective model. A similar fourth-order perturbative analysis is performed for the depleted Anderson lattice in the limit of strong hybridization. Even in a parameter regime where the Schrieffer-Wolff transformation does not apply, this yields the same effective theory albeit with a different coupling constant.
description: 14 pages, 5 figures
Temperature dependent creation of nitrogen-vacancy centers in CVD diamond layers
Creators: name: Tallaire, A.
name: Lesik, M.
name: Jacques, V.
name: Pezzagna, S.
name: Mille, V.
name: Brinza, O.
name: Meijer, J.
name: Abel, B.
name: Roch, J. -F.
name: Gicquel, A.
name: Achard, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: In this work, we explore the ability of plasma assisted chemical vapor deposition (PACVD) operating under high power densities to produce thin high-quality diamond layers with a controlled doping with negatively-charged nitrogen-vacancy (NV-) centers. This luminescent defect possesses specific physical characteristics that make it suitable as an addressable solid-state electron spin for measuring magnetic fields with unprecedented sensitivity. To this aim, a relatively large number of NV- centers (> 10^12 cm^-3) should ideally be located in a thin diamond layer (a few tens of nm) close to the surface which is particularly challenging to achieve with the PACVD technique. Here we show that intentional temperature variations can be exploited to tune NV- creation efficiency during growth, allowing engineering complex stacking structures with a variable doping. Because such a temperature variation can be performed quickly and without any change of the gas phase composition, thin layers can be grown. Measurements show that despite the temperature variations, the luminescent centers incorporated using this technique exhibit spin coherence properties similar to those reached in ultra-pure bulk crystals, which suggests that they could be successfully employed in magnetometry applications.
description: 13 pages, 5 figures, corrected bibliography
White Matter Lesion Progression: Genome-Wide Search for Genetic Influences
Creators: name: Wolf, Christiane
name: Adams, Hieab H.H.
name: Buckley, Brendan M.
name: Moran, Chris
name: Niessen, Wiro J.
name: Hofer, Edith
name: Heiss, Gerardo
name: Hofman, Albert
name: van Duijn, Cornelia M.
name: Phan, Thanh
name: Dufouil, Carole
name: Mazoyer, Bernard
name: Verhaaren, Benjamin F.J.
name: Srikanth, Velandai
name: Chauhan, Ganesh
name: de Craen, Anton J.M.
name: DeCarli, Charles
name: Gudnason, Vilmundur
name: Martinez, Oliver
name: Trompet, Stella
name: Fornage, Myriam
name: Yang, Qiong
name: Cavalieri, Margherita
name: Ford, Ian
name: Amouyel, Philippe
name: Gottesman, Rebecca F.
name: Lumley, Thomas
name: Sigurdsson, Sigurdur
name: Callisaya, Michele
name: Freudenberger, Paul
name: Bis, Joshua C.
name: Beiser, Alexa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: White matter lesion (WML) progression on magnetic resonance imaging (MRI) is related to cognitive decline and stroke, but its determinants besides baseline WML burden are largely unknown. Here, we estimated heritability of WML progression, and sought common genetic variants associated with WML progression in elderly participants from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
Superconductivity of 2.2 K under Pressure in Helimagnet CrAs
Creators: name: Kotegawa, Hisashi
name: Nakahara, Shingo
name: Tou, Hideki
name: Sugawara, Hitoshi
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report resistivity measurements of the helimagnet CrAs under pressures. The helimagnetic transition with T_N ~ 265 K at ambient pressure is completely suppressed above a critical pressure of P_c ~ 0.7 GPa, and superconductivity is observed at ~2.2 K for zero resistance, which exists in a wide pressure range extending beyond 3 GPa. Both the upper critical field H_{c2} and the coefficient A in the resistivity increase toward P_c, suggesting that the superconductivity of CrAs is mediated by electronic correlations enhanced in the vicinity of the helimagnetic phase.
description: 4pages, 4 figures
Incorporating Measurement Nonequivalence in a Cross-Study Latent Growth Curve Analysis
Creators: name: Curran, Patrick J.
name: Flora, David B.
name: Hussong, Andrea M.
name: Edwards, Michael C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: A large literature emphasizes the importance of testing for measurement equivalence in scales that may be used as observed variables in structural equation modeling applications. When the same construct is measured across more than one developmental period, as in a longitudinal study, it can be especially critical to establish measurement equivalence, or invariance, across the developmental periods. Similarly, when data from more than one study are combined into a single analysis, it is again important to assess measurement equivalence across the data sources. Yet, how to incorporate non-equivalence when it is discovered is not well described for applied researchers. Here, we present an item response theory approach that can be used to create scale scores from measures while explicitly accounting for non-equivalence. We demonstrate these methods in the context of a latent curve analysis in which data from two separate studies are combined to create a single longitudinal model spanning several developmental periods.
Modeling Change in the Presence of Nonrandomly Missing Data: Evaluating a Shared Parameter Mixture Model
Creators: name: Baldwin, Scott A.
name: Gottfredson, Nisha C.
name: Bauer, Daniel J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: In longitudinal research, interest often centers on individual trajectories of change over time. When there is missing data, a concern is whether data are systematically missing as a function of the individual trajectories. Such a missing data process, termed random coefficient-dependent missingness, is statistically non-ignorable and can bias parameter estimates obtained from conventional growth models that assume missing data are missing at random. This paper describes a shared-parameter mixture model (SPMM) for testing the sensitivity of growth model parameter estimates to a random coefficient-dependent missingness mechanism. Simulations show that the SPMM recovers trajectory estimates as well as or better than a standard growth model across a range of missing data conditions. The paper concludes with practical advice for longitudinal data analysts.
Structure of Gαi1 Bound to a GDP-Selective Peptide Provides Insight into Guanine Nucleotide Exchange
Creators: name: Johnston, Christopher A.
name: Jezyk, Mark R.
name: Siderovski, David P.
name: Harden, T. Kendall
name: Willard, Francis S.
name: Watts, Val J.
name: Jones, Miller B.
name: Ramer, J. Kevin
name: Bodor, Erik T.
name: Sondek, John
name: Fredericks, Zoey
name: Blaesius, Rainer
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: Heterotrimeric G-proteins are molecular switches that regulate numerous signaling pathways involved in cellular physiology. This characteristic is achieved by the adoption of two principal states: an inactive, GDP-bound and an active, GTP-bound state. Under basal conditions G-proteins exist in the inactive GDP-bound state, thus nucleotide exchange is crucial to the onset of signaling. Despite our understanding of G-protein signaling pathways, the mechanism of nucleotide exchange remains elusive. We employed phage display technology to identify nucleotide-state-dependent Gα binding peptides. Herein, we report a GDP-selective Gα-binding peptide, KB-752, that enhances spontaneous nucleotide exchange of Gαi subunits. Structural determination of the Gαi1/peptide complex reveals unique changes in the Gα switch regions predicted to enhance nucleotide exchange by creating a GDP dissociation route. Our results cast light onto a potential mechanism by which Gα subunits adopt a conformation suitable for nucleotide exchange.
A Conformational Transition State Accompanies Tryptophan Activation by B. stearothermophilus Tryptophanyl-tRNA Synthetase
Creators: name: Weinreb, Violetta
name: Li, Li
name: Kuhlman, Brian
name: Carter, Charles W.
name: Kapustina, Maryna
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: B. stearothermophilus tryptophanyl-tRNA synthetase catalysis proceeds via high-energy protein conformations. Unliganded MD trajectories of the Pre-Transition-state complex with Mg2+•ATP and the (post) transition-state analog complex with adenosine tetraphosphate relax rapidly in opposite directions, the former regressing, the latter progressing along the structural reaction coordinate. The two crystal structures (RMSD 0.7 Å) therefore lie on opposite sides of a conformational free energy maximum as the chemical transition state forms. SNAPP analysis illustrates the complexity of the associated long-range conformational coupling. Switching interactions in four non-polar core regions are locally isoenergetic throughout the transition. Different configurations, however, propagate their effects to unfavorable, longer-range interactions at the molecular surface. Designed mutation shows that switching interactions enhance the rate, perhaps by destabilizing the ground state immediately before the transition state and limiting non-productive diffusion before and after the chemical transition state, thereby reducing the activation entropy. This paradigm may apply broadly to energy-transducing enzymes.
Data Stewardship, OVGU. Data Stewardship als kooperative Forschungsunterstützung. FDM Sachsen-Anhalt.
Creators: name: Strauch-Davey, Annette
Publisher: name: Zenodo
Year: 2023
Subjects: FDM
FDM Sachsen-Anhalt
Forschungsdatenmanagement Sachsen-Anhalt
Open Science
RDM
Research Data Management
Research Data Management Sachsen-Anhalt
Research Data Management Saxony-Anhalt
FDM Task Force
RDM Task Force
Sachsen-Anhalt
Saxony-Anhalt
Forschungsdatenmanagement
FAIR
FAIR data

description: Die Präsentationsfolien zum "Data Stewardship, OVGU. Data Stewardship als kooperative Forschungsunterstützung." sind im Rahmen des ersten Treffens der FDM Sachsen-Anhalt Task Force am 02.März 2023 entstanden.
Horava-Lifshitz cosmology, entropic interpretation and quark-hadron phase transition
Creators: name: Kheyri, F.
name: Khodadi, M.
name: Sepangi, H. R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Based on the assumptions of the standard model of cosmology, a phase transition associated with chiral symmetry breaking after the electroweak transition has occurred at approximately $10μ$ seconds after the Big Bang to convert a plasma of free quarks and gluons into hadrons. We consider such a phase transition in the context of a deformed Horava-Lifshitz cosmology. The Friedmann equation for the deformed Horava-Lifshitz universe is obtained using the entropic interpretation of gravity, proposed by Verlinde. We investigate the effects of the parameter $ω$ appearing in the theory on the evolution of the physical quantities relevant to a description of the early universe, namely, the energy density and temperature before, during and after the phase transition. Finally, we study the cross-over phase transition in both high and low temperature regions in view of the recent lattice QCD simulations data.
description: 17 pages, 7 figures. arXiv admin note: text overlap with arXiv:0710.0354 by other authors
Structural and Thermodynamic Basis for Enhanced DNA Binding by a Promiscuous Mutant EcoRI Endonuclease
Creators: name: Jen-Jacobson, Linda
name: Sapienza, Paul J.
name: Rosenberg, John M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Promiscuous mutant EcoRI endonucleases bind to the canonical site GAATTC more tightly than does the wild-type endonuclease, yet cleave variant (EcoRI*) sites more rapidly than does wild-type. The crystal structure of the A138T promiscuous mutant homodimer in complex with a GAATTC site is nearly identical to that of the wild-type complex, except that the Thr138 side chains make novel packing interactions with bases in the 5′-flanking regions outside the recognition hexanucleotide, while excluding two bound water molecules seen in the wild-type complex. Molecular dynamics simulations confirm exclusion of these waters. The structure and simulations suggest multiple possible reasons why binding of A138T protein to the GAATTC site has ΔS° more favorable and ΔH° less favorable than for wild-type endonuclease binding. The novel interactions of Thr138 with flanking bases may permit A138T, unlike wild-type enzyme, to form complexes with EcoRI* sites that structurally resemble the specific wild-type complex with GAATTC.
A new ferulol derivative isolated from the aerial parts of Ferulago nodosa (L.) Boiss. growing in Sicily (Italy)
Creators: name: Badalamenti, Natale
name: Vaglica, Alessandro
name: Maggio, Antonella
name: Bruno, Maurizio
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Ferulago nodosa (L.) Boiss. (Apiaceae) is a species occurring in the Balkan-Tyrrhenian area being present in Crete, Greece, Albania, and probably in Macedonia. Although the western disjointed population of Sicily has been classified as an endemic sub-species, F. nodosa subsp. geniculata (Guss.) Troia & Raimondo, it is not officially accepted. From the aerial parts of the Sicilian accession of this species four known metabolites (1–4), and a new ferulol derivative (5), were isolated and characterized. The structure of the new compounds was determined by mean of extensive NMR spectroscopic experiments.
Ab Initio Folding of Proteins with All-Atom Discrete Molecular Dynamics
Creators: name: Dokholyan, Nikolay V.
name: Ding, Feng
name: Nie, Huifen
name: Tsao, Douglas
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Discrete molecular dynamics (DMD) is a rapid sampling method used in protein folding and aggregation studies. Until now, DMD was used to perform simulations of simplified protein models in conjunction with structure-based force fields. Here, we develop an all-atom protein model and a transferable force field featuring packing, solvation, and environment-dependent hydrogen bond interactions. Using the replica exchange method, we perform folding simulations of six small proteins (20–60 residues) with distinct native structures. In all cases, native or near-native states are reached in simulations. For three small proteins, multiple folding transitions are observed and the computationally-characterized thermodynamics are in quantitative agreement with experiments. The predictive power of all-atom DMD highlights the importance of environment-dependent hydrogen bond interactions in modeling protein folding. The developed approach can be used for accurate and rapid sampling of conformational spaces of proteins and protein-protein complexes, and applied to protein engineering and design of protein-protein interactions.
Serum and urine osmolality: 8 hours, 24 hours and 1-month sample stability
Creators: name: Đuras, Anamarija
name: Kocijan, Valentina Cesar
name: Rade, Anamarija
name: Lipovec, Renata
name: Ostroški, Ivanka
name: Biljak, Vanja Radišić
name: Šimundić, Ana-Maria
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy
subject: Hematology

description: The body of literature varies significantly regarding serum and urine osmolality stability. Therefore, our aim was to investigate the stability of serum and urine osmolality at different temperatures (room temperature (RT) 4–8 °C, −20 °C) and time conditions (8 h, 24 h, 1 month). The stability study was conducted following the CRESS guidelines, including 40 serum and urine samples. Samples were aliquoted into three aliquots and stored as follows: primary tube stored at RT for 8 h; two capped aliquots stored at 4–8 °C for 8 h and 24 h; one aliquot stored at −20 °C for 1 month. To minimize imprecision error, serum and urine osmolality were measured by the freezing point depression method in triplicate on OSMOMAT 3000 (Gonotech, Germany) analyzer. Percentage difference (PD%) against baseline measurement was calculated. Deviations were assessed against a reference change value of 5.0%. The PD% for serum and urine osmolality was below 2.0% for all time/temperature conditions. For serum samples: primary tube after 8 h at RT PD% (95% CI) = 0.0% (−0.3, 0.2%); 8 h at 4–8 °C PD% (95% CI) = −0.4% (−0.7, 0.0%); 24 h at 4–8 °C PD% (95% CI) = −0.7% (−0.7, −0.6%); 1 month at −20 °C PD% (95% CI) = −2.1% (−2.4, −1.5%). For urine samples: after 8 h at RT PD% (95% CI) =0.6% (0.2, 0.9%); 8 h at 4–8 °C PD% (95% CI) = −0.2% (−0.5, 0.1%); 24 h at 4–8 °C PD% (95% CI) = −0.2% (−0.5, 0.0%); 1 month at −20 °C PD% (95% CI) = −2.0% (−3.0, −1.0%). Changes in osmolality for tested conditions for serum and urine samples, were within acceptance criteria. Reflex and add-on osmolality testing can be performed within the same day in samples kept at RT for 8 h in primary tube and within 24 h, in aliquoted refrigerated samples, without compromising the reliability of test results. For longer storage, samples should be kept at −20 °C.
Computer-Based Redesign of a β Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo β Sheet Design
Creators: name: Wang, Huanchen
name: Hu, Xiaozhen
name: Kuhlman, Brian
name: Ke, Hengming
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The de novo design of globular β-sheet proteins remains largely an unsolved problem. It is unclear if most designs are failing because the designed sequences do not have favorable energies in the target conformations or if more emphasis should be placed on negative design, i.e. explicitly identifying sequences that have poor energies when adopting undesired conformations. We tested if we could redesign the sequence of a naturally occurring β-sheet protein, tenascin, with a design algorithm that does not include explicit negative design. Denaturation experiments indicate that the designs are significantly more stable than the wild type protein and the crystal structure of one design closely matches the design model. These results suggest that extensive negative design is not required to create well-folded β-sandwich proteins. However, it is important to note that negative design elements may be encoded in the conformation of the protein backbone which was preserved from the wild type protein.
New cycloartane coronalyl acetate and other terpenoids with anti-inflammatory activity from the leaves of Vietnamese Gardenia philastrei
Creators: name: Hung, Nguyen Khac
name: Quang, Dang Ngoc
name: Quang, Le Dang
name: Minh, Tran Thi
name: Dung, Ta Ngoc
name: Duong, Pham Quang
name: Tung, Nguyen Huu
name: Hoang, Vu Dinh
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Phytochemical study on the methanolic extract of the leaves of Vietnamese plant Gardenia philastrei Pierre ex Pit. has led to the isolation of a new cycloartane coronalyl acetate (1) together with six known ones, coronlolide methyl ester (2), sootepin D (3), coronalolide (4), coronalolic acid (5), sootepin G (6) and 23-deoxojessic acid (7). Their structures were elucidated by a combination of 2 D NMR and HR-ESI-MS spectroscopies. These compounds (1-7) were tested for their anti-inflammatory activity. The result showed that six compounds (1-6) inhibit LPS-induced nitric oxide production in RAW264.7 macrophages with their IC50 values ranging from 3.76 − 75.47 µg/mL. This is the first report on the chemical constituents and anti-inflammatory activity of the G. philastrei.
Definition and evolution of transverse momentum dependent distribution of twist-three
Creators: name: Rodini, Simone
name: Vladimirov, Alexey
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: Factorization, Renormalization Group, Parton Distributions
subject: 530 Physik

description: We present an in-depth analysis of transverse momentum dependent (TMD) distributions of twist-three. In particular, we focus on evolution equations, symmetry relations, parameterization, interpretation, small-b asymptotic behaviour and the structure of singularities. The starting point of discussion are the correlators with the definite TMD-twist. By considering suitable combinations of these correlators, we introduce physical TMD distribution of twist-three that can be used for practical applications. We also establish relations with generic TMD distribution of twist-three, and demonstrate that their evolution equations are autonomous in the large-Nc limit.
Two new α-pyrone-containing polyketides isolated from the fungus Aspergillus aureoterreus
Creators: name: Zhou, Beiping
name: Tong, Qingyi
name: Zang, Yi
name: Zhu, Honghui
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Space Science
Physical Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Two undescribed α-pyrone-containing polyketide derivatives designated aurovertins V (1) and W (2), and a known analogue (3), were isolated from the fungus Aspergillus aureoterreus. Their structures including the absolute configuration were elucidated on the basis of extensive spectroscopic methods and theoretical ECD calculation. Compound 1 is the first example of aurovertins with a 7R configuration, whereas 2 comprises a S configuration for C-6 and a Z geometry of the double bond Δ8. Both 1 and 2 showed no cytotoxicity against human cancer cell lines HL-60, SU-DHL-2 and U266) at the concentration of 20.0 μM.