cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Enantiomer-specific isotope analysis of D- and L-alanine: Nitrogen isotopic hetero- and homogeneity in microbial and chemical processes
Creators: name: Takano, Yoshinori
name: Chikaraishi, Yoshito
name: Ohkouchi, Naohiko
Publisher: name: arXiv
Year: 2013
Subjects: subject: Biomolecules (q-bio.BM)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Biological sciences
subject: FOS: Physical sciences
subject: http://www.kyoto-up.or.jp/book.php?lang=en

description: Nitrogen isotopic hetero- and homogeneity of D-α-alanine and L-α-alanine were investigated in microbial processes in the domain Bacteria and in chemical processes in symmetric organic synthesis. D-alanine is an enantiomer that is physiologically essential for microbial growth and metabolic maintenance. The nitrogen isotopic difference Δ15ND-L (defined as δ15ND-Ala - δ15NL-Ala) in peptidoglycan amino acids in bacteria such as the representative gram-positive phyla Firmicutes and Actinobacteria (Enterococcus faecalis, Staphylococcus aureus, Staphylococcus staphylolyticus, Lactobacillus acidophilus, Bacillus subtilis, Micrococcus luteus, and Streptomyces sp.) tended to be 15N-depleted in D-alanine (Δ15ND-L < -2.0 permil). These results suggest that the composition of isotopically heterogeneous components in these bacteria is primarily controlled by enzymatic pathways prior to formation of the bacterial cell wall. In contrast, the Δ15ND-L of racemic alanine in the chemical pathway during the nucleophilic substitution reaction (SN1 type) between 2-bromopropionic acid and ammonia identified fully homogeneous components for each enantiomer. The novel enantiomer-specific isotopic analysis (ESIA) method is useful in determining the origins of chirality in biogenic and abiogenic processes and is applicable to enantiomer studies. -- Keywords: D-alanine, microbial process, chemical process, nitrogen isotopic composition, enantiomer-specific isotope analysis (ESIA)
description: ISBN: 9784876989607
GPU-Unterstützung in der Bibliotheksentwicklung
Creators: name: Krzikalla, Olaf
name: Rempke, Arne
name: Mohnke, Jasmin
Publisher: name: Zenodo
Year: 2023

description: GPUs bilden im wissenschaftlichen Hochleistungsrechnen mittlerweile eine wesentliche Komponente bei hochparallelen Berechnungen. Konsequenterweise ist die im DLR e.V. entwickelte, speziell auf die Bedürfnisse der Luft- und Raumfahrt zugeschnittene C+±Bibliothek “Spliss” zur Lösung linearer Gleichungssysteme von Anfang an auf GPU-Unterstützung ausgelegt worden. Inzwischen ist Spliss bereits in Version 2 verfügbar und wird in einer Vielzahl von DLR-internen Strömungslösern und anverwandter Software eingesetzt. Der Vortrag richtet seinen Fokus auf die GPU-Unterstützung dieser Bibliothek. Wir beschreiben, wie das Alpaka-Framework das Schreiben geräte-unabhängigen Codes unterstützt und auch, an welche Grenzen wir dabei gestossen sind. Weiterhin zeigen wir die Einbindung von Technologien wie z.B. CUDA-aware MPI und deren Effekte auf die Recheneffizienz. Schlussendlich erläutern wir unseren Weg, den Nutzern eine möglichst transparente GPU-Unterstützung zu bieten, so dass diese bei der Einbindung von Spliss keine GPU-spezifischen Anpassungen an ihren Anwendungen oder Toolchains vornehmen müssen.
Supplementary tables from Analysis of mechanotransduction dynamics during combined mechanical stimulation and modulation of the extracellular-regulated kinase cascade uncovers hidden information within the signalling noise
Creators: name: Ascolani, Gianluca
name: Skerry, Timothy M.
name: Lacroix, Damien
name: Dall'Ara, Enrico
name: Shuaib, Aban
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Biochemistry
subject: 110601 Biomechanics
subject: FOS: Health sciences
subject: Computational Biology

description: Osteoporosis is a bone disease characterized by brittle bone and increased fracture incidence. With ageing societies worldwide, the disease presents a high burden on health systems. Furthermore, there are limited treatments for osteoporosis with just two anabolic pharmacological agents approved by the US Food and Drug Administration. Healthy bones are believed to be maintained via an intricate relationship between dual biochemical and mechanical (bio-mechanical) stimulations. It is widely considered that osteoporosis emerges as a result of disturbances to said relationship. The mechanotransduction process is key to this balance, and disruption of its dynamics in bone cells plays a role in osteoporosis development. Nonetheless, the exact details and mechanisms that drive and secure the health of bones are still elusive at the cellular and molecular scales. This study examined the dual modulation of mechanical stimulation and mechanotransduction activation dynamics in an osteoblast (OB). The aim was to find patterns of mechanotransduction dynamics demonstrating a significant change that can be mapped to alterations in the OB responses, specifically at the level of gene expression and osteogenic markers such as alkaline phosphatase. This was achieved using a three-dimensional hybrid multiscale computational model simulating mechanotransduction in the OB and its interaction with the extracellular matrix, combined with a numerical analytical technique. The model and the analysis method predict that within the noise of mechanotransduction, owing to modulation of the bio-mechanical stimulus and consequent gene expression, there are unique events that provide signatures for a shift in the system's dynamics. Furthermore, the study uncovered molecular interactions that can be potential drug targets.
easydb. Flexible framework for building metadata and media repositories. Use case: Research data.
Creators: name: Strauch, Annette
name: Kloppmann, Jens
name: Kastner, Charlotte
Publisher: name: Zenodo
Year: 2020
Subjects: easydb
FDM
Forschungsdaten
Forschungsdatenmanagement
RDM
Research Data Management

description: easydb
 Flexible framework for building metadata and media
 repositories
 Use case : Research data (Content: Programmfabrik GmbH; Translation: Annette Strauch)
Chronic Obstructive Pulmonary Disease (COPD) is associated with pulmonary artery stiffness - the MESA COPD study
Creators: name: Bluemke, David A.
name: Lima, Joao A.
name: Prince, Martin R.
name: Barr, Graham
name: Liu, Chia-Ying
name: Parikh, Megha
name: Gomes, Antoinette S.
name: Vogel-Claussen, Jens
Publisher: name: Columbia University
Year: 2013
Subjects: Epidemiology
Medicine

description: This study seeks to evaluate indices of pulmonary artery (PA) stiffness in patients with COPD and compare with normal controls. We hypothesize that patients with COPD would have increased pulmonary artery stiffness. To test this we determine the pulmonary artery area change (distensibility in %) by cardiac MRI and relate the distensibility to a wide range of severity of COPD.
The MESA COPD Study recruited 290 patients (135 patients of various COPD severity and 155 controls) from four field centers in the US, age 50-79 years with ≥10 pack-years of smoking, all free of clinical cardiovascular disease. COPD was defined on post-bronchodilator spirometry by GOLD criteria (FEV1/FVC <70%, FEV1 % predicted >80% = mild, 50-80%=moderate, <50%=severe). All participants underwent full-lung CTs. Percent emphysema was defined as the percentage of total voxels within the lung field that fell below -910 Hounsfield units. MRI studies were performed using 1.5T scanners. To measure ventricular function, the entire heart was imaged in short-axis orientation using a retrospectively gated steady-state free precession sequence. Phase-contrast images of the pulmonary arteries were obtained using a segmented fast gradient echo sequence with free breathing and analyzed quantitatively using dedicated software (FLOW, Medis). Distensibility of the pulmonary vessels (in %) are measured by the following formula, 100×(maximum PA area-minimum PA area)/minimum PA area. The base model (model 1) was adjusted for age, gender, height, weight, race/ethnicity and cohort of selection, given relationships of COPD severity to the pulmonary distensibility. We then additionally adjusted for smoking status, pack-years, diabetes mellitus, hypertension, oxygen saturation, LDL, HDL and statin use (model 2).
Table 1 summarizes the clinical characteristics of 290 participants stratified by COPD severity. Distensibility of the main, right and left PA was reduced in COPD compared to controls in both models (Table 2). Main and right pulmonary distensibilities were inversely related to percent emphysema after minimal adjustment (model 1, P=0.21 and 0.07, respectively) and similar trends with statistical significance in the full model (model 2, P=0.049 and 0.01, respectively). Pulmonary distensibilities was positively associated with the percent predicted FEV1 but only left PA attain statistical significance after base adjustment (model 1, P=0.047).
We conclude that in COPD patients without overt cardiovascular disease, pulmonary artery distensibility is reduced. Higher pulmonary arterial stiffness also correlated with the percent emphysema on CT scan and FEV1.
Initial carrier-envelope phase of few-cycle pulses determined by THz emission from air plasma
Creators: name: Xu, Rongjie
name: Bai, Ya
name: Song, Liwei
name: Liu, Peng
name: Li, Ruxin
name: Xu, Zhizhan
Publisher: name: arXiv
Year: 2013
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The evolution of THz waveform generated in air plasma provides a sensitive probe to the variation of the carrier envelope phase (CEP) of propagating intense few-cycle pulses. Our experimental observation and calculation reveal that the number and positions of the inversion of THz waveform are dependent on the initial CEP, which is near 0.5π constantly under varied input pulse energies when two inversions of THz waveform in air plasma become one. This provides a method of measuring the initial CEP in an accuracy that is only limited by the stability of the driving few-cycle pulses.
description: 13 pages, 4 figures
Copy number variation genotyping using family information
Creators: name: Darvishi, Katayoon
name: Mills, Ryan E.
name: Lee, Charles
name: Raby, Benjamin A.
name: Chu, Jen-Hwa
name: Rogers, Angela
name: Ionita-Laza, Iuliana
Publisher: name: Columbia University
Year: 2013
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Statistics
subject: FOS: Mathematics

description: Background: In recent years there has been a growing interest in the role of copy number variations (CNV) in genetic diseases. Though there has been rapid development of technologies and statistical methods devoted to detection in CNVs from array data, the inherent challenges in data quality associated with most hybridization techniques remains a challenging problem in CNV association studies. Results: To help address these data quality issues in the context of family-based association studies, we introduce a statistical framework for the intensity-based array data that takes into account the family information for copy-number assignment. The method is an adaptation of traditional methods for modeling SNP genotype data that assume Gaussian mixture model, whereby CNV calling is performed for all family members simultaneously and leveraging within family-data to reduce CNV calls that are incompatible with Mendelian inheritance while still allowing de-novo CNVs. Applying this method to simulation studies and a genome-wide association study in asthma, we find that our approach significantly improves CNV calls accuracy, and reduces the Mendelian inconsistency rates and false positive genotype calls. The results were validated using qPCR experiments. Conclusions: In conclusion, we have demonstrated that the use of family information can improve the quality of CNV calling and hopefully give more powerful association test of CNVs.
"combined.tgz" of "Combination of Differential D^{*\pm} Cross-Section Measurements in Deep-Inelastic ep Scattering at HERA"
Creators: name: H1 Collaboration
name: ZEUS Collaboration
Publisher: name: HEPData
Year: 2016

description: Data tables in ASCII format, including all sources of correlated uncertainties
description: DESY-HERA. H1 and ZEUS have published single-differential cross sections for inclusive $D^{*\pm}$-meson production in deep-inelastic $ep$ scattering at HERA from their respective final data sets. These cross sections are combined in the common visible phase-space region of photon virtuality $Q^2$ > 5 GeV$^2$, electron inelasticity 0.02 < $y$ < 0.7 and the $D^{*\pm}$ meson's transverse momentum $p_T$ ($D^*$) > 1.5 GeV and pseudorapidity $|\eta(D^*)| < 1.5$. The combination procedure takes into account all correlations, yielding significantly reduced experimental uncertainties. Double-differential cross sections d$^2\sigma/$d$Q^2$d$y$ are combined with earlier $D^{*\pm}$ data, extending the kinematic range down to $Q^2$ > 1.5 GeV$^2$. The numbers in the tables below have been extracted from the LaTeX source of arXiv:1503.06042v2.
¿De quién es la falta de ética del mayor o del iniciado?
Creators: name: Borges Bartutis, María Vicenta
Publisher: name: Comparative Cultural Studies - European and Latin American Perspectives
Year: 2018

description: The objective of this paper is to illustrate the current reality of the Ocha-Ifá Rule in Cuba, which is characterized by the diversity mediated by modernity, which together with other social factors and syncretism identifies a social problem originated, in principle, by the circumstance in which the Spanish white man arrived in Cuba, the way in which he brought the African black and the conditions in which he kept him enslaved; nevertheless, the new reality, black, with skill and wisdom preserves and protects their traditions, their culture. Thus, the expansion of the primary oral transmission of African culture begins in the process of “transculturation”; At present, despite the survival of this religious practice, the modern trend has changed the coexistence between the branches and the actions of practitioners, who with the intention of making their actions prevail, set excessive prices for the established ritual ceremonies. Or they constantly violate duties and rights, thus deforming what is stipulated in the Ocha-Ifá Rule. The above is the result of the «boom» of the Ocha-Ifá Rule «Santería»; event that, sometimes for some implies a fashion and for others the spirituality of the practitioner, which differs from the ethics, respect and confidence of the believer in his practice, therefore the contrast in Cuba between the historical moment is questioned lived by those who preceded us; the silent, discreet scenario in which, for various reasons, they guarded the religion and the current context in which the Ocha-Ifá Rule is practiced.
description: Comparative Cultural Studies - European and Latin American Perspectives, Vol. 3 No. 6 (2018)
Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts
Creators: name: Vardarajan, Badri
name: Vergote, David
name: Tissir, Fadel
name: Logue, Mark
name: Yang, Jing
name: Daude, Nathalie
name: Ando, Kunie
name: Rogaeva, Ekaterina
name: Lee, Joseph H.
name: Cheng, Rong
name: Brion, Jean-Pierre
name: Ghani, Mahdi
name: Shi, Beipei
name: Baldwin, Clinton
name: Kar, Satyabrata
name: Mayeux, Richard Paul
name: Fraser, Paul
name: Goffinet, André
name: George-Hyslop, Peter St
name: Farrer, Lindsay
name: Westaway, David
Publisher: name: Columbia University
Year: 2013
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Background: P73 belongs to the p53 family of cell survival regulators with the corresponding locus Trp73 producing the N-terminally distinct isoforms, TAp73 and DeltaNp73. Recently, two studies have implicated the murine Trp73 in the modulation in phospho-tau accumulation in aged wild type mice and in young mice modeling Alzheimer’s disease (AD) suggesting that Trp73, particularly the DeltaNp73 isoform, links the accumulation of amyloid peptides to the creation of neurofibrillary tangles (NFTs). Here, we reevaluated tau pathologies in the same TgCRND8 mouse model as the previous studies. Results: Despite the use of the same animal models, our in vivo studies failed to demonstrate biochemical or histological evidence for misprocessing of tau in young compound Trp73+/- + TgCRND8 mice or in aged Trp73+/- mice analyzed at the ages reported previously, or older. Secondly, we analyzed an additional mouse model where the DeltaNp73 was specifically deleted and confirmed a lack of impact of the DeltaNp73 allele, either in heterozygous or homozygous form, upon tau pathology in aged mice. Lastly, we also examined human TP73 for single nucleotide polymorphisms (SNPs) and/or copy number variants in a meta-analysis of 10 AD genome-wide association datasets. No SNPs reached significance after correction for multiple testing and no duplications/deletions in TP73 were found in 549 cases of AD and 544 non-demented controls. Conclusion: Our results fail to support P73 as a contributor to AD pathogenesis.
Emancipación o Metamorfosis: Consecuencia postcolonial de la Trata Negrera de la Esclavitud
Creators: name: Aboy Domingo, Nelson
Publisher: name: Comparative Cultural Studies - European and Latin American Perspectives
Year: 2018

description: The postcolonial emancipation in Africa implies the insertion of ethnos elements into the dominant cultural system. The slaves rescued by the British Navy during the legal Trade were multiple and dissimilar to between them concentrated in coastal cities that can not subsist in particular minorities, also, the need for social integration; and they were, in turn, incompatible and incompetent in the face of British and learned culture. The British were schooled in English and converted to Christianity, as part of the “civilizing” process. So, they substituted each and every one of their diverse cultural and religious identities, for an ethnocultural colonial invention, that granted official weight and that since then was denominated: Yoruba, to all the emancipated ones concentrated in the British colonial demarcation of Yorubaland (Yoruba Earth). Because of the relevance and egocentrism that the official British discourse of the time gave to this fallacy of the African indigenous tradition, in the last decades (1980-2010) it has migrated to America and other latitudes, for the purpose of a new colonization of the cultural identities of African antecedents that are conserved in the African-American diasporas and, paradoxically, they call themselves: Yoruba traditionalists, as false bearers of the oldest autochthonous traditions of the original ancestral cultures. The present material tries to locate historical facts and events that clarify the colonial origin of this human conglomerate, which call themselves Yorubas; at the same time, to demonstrate that they are only carriers of the egocentric and colonizing pattern of cultural thought, which since then they inherited from the metamorphosis they suffered, rather than from a real emancipation and conservation of their ancestral cultures.
description: Comparative Cultural Studies - European and Latin American Perspectives, Vol. 3 No. 6 (2018)
Quantum Entanglement in Carbon-Carbon, Carbon-Phosphorus and Silicon-Silicon Bonds
Creators: name: Mottet, Matthieu
name: Tecmer, Pawel
name: Boguslawski, Katharina
name: Legeza, Ors
name: Reiher, Markus
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: The chemical bond is an important local concept to understand chemical compounds and processes. Unfortunately, like most local concepts, the chemical bond and the bond order do not correspond to any physical observable and thus cannot be determined as an expectation value of a quantum chemical operator. We recently demonstrated [Boguslawski et al., J. Chem. Theory Comput., 2013, 9, 2959--2973] that one- and two-orbital-based entanglement measures can be applied to interpret electronic wave functions in terms of orbital correlation. Orbital entanglement emerged to be a powerful tool to provide a qualitative understanding of bond-forming and bond-breaking processes, and allowed for an estimation of bond orders of simple diatomic molecules beyond the classical bonding models. In this article we demonstrate that the orbital entanglement analysis can be extended to polyatomic molecules to understand chemical bonding.
description: 9 figures, 8 pages
"beauty.tgz" of "Combination of Differential D^{*\pm} Cross-Section Measurements in Deep-Inelastic ep Scattering at HERA"
Creators: name: H1 Collaboration
name: ZEUS Collaboration
Publisher: name: HEPData
Year: 2016

description: Predicted beauty cross cross sections
description: DESY-HERA. H1 and ZEUS have published single-differential cross sections for inclusive $D^{*\pm}$-meson production in deep-inelastic $ep$ scattering at HERA from their respective final data sets. These cross sections are combined in the common visible phase-space region of photon virtuality $Q^2$ > 5 GeV$^2$, electron inelasticity 0.02 < $y$ < 0.7 and the $D^{*\pm}$ meson's transverse momentum $p_T$ ($D^*$) > 1.5 GeV and pseudorapidity $|\eta(D^*)| < 1.5$. The combination procedure takes into account all correlations, yielding significantly reduced experimental uncertainties. Double-differential cross sections d$^2\sigma/$d$Q^2$d$y$ are combined with earlier $D^{*\pm}$ data, extending the kinematic range down to $Q^2$ > 1.5 GeV$^2$. The numbers in the tables below have been extracted from the LaTeX source of arXiv:1503.06042v2.
Impact of transport sector electrification on the Laotian power system
Creators: name: Pholsena, Latsayakone
name: Nanthavong, Khamphone
name: Phommachanh, Sounthisack
name: Sridharan, Vignesh
Publisher: name: Zenodo
Year: 2025

description: Lao PDR (Laos) is transforming its energy and transport sectors through clean energy policies and promoting electric vehicles (EVs). In 2023, the country’s electricity landscape features a generation mix dominated by hydropower and significant cross-border energy exchanges. The emerging EV ecosystem signals a critical infrastructure transition. Our analysis reveals that EV adoption could increase electricity demand by ~2.2 times by 2055, potentially straining the current system. However, this shift offers substantial benefits, including reduced fossil fuel dependence, potential fuel import savings that can compensate for electricity imports, and lower carbon emissions. To address Laos’ energy transition challenges, policymakers should focus on improving regional transmission capacity and developing strategic EV adoption plans.
La Oralidad, los ecos en el Tiempo
Creators: name: Robinson Echevarría, Vicente
Publisher: name: Comparative Cultural Studies - European and Latin American Perspectives
Year: 2018

description: The oral tradition is deeply rooted in the country, the monumental work of religions coming from Africa were transmitted through orality. Starting from word, people leave their witness that passed down from generation to generation through time, real stories, legends, tales, and myths are transmitted and re-created even by time, receiving relevance in the popular imaginary. The community of Surgidero de Batabanó has been included in this practice. There are several stories about it with central core, other fantastic based on the imagination and the popular belief. The contribution re-creates three stories that have been told in the community since the first years of the last century (XX), that have been heard in the homely silence, during the winter nights when families gather and bring out the same. The stories by Juan Oliven, la Familia Fontanel and Policarpo Sandoval are told in this manner. They originate from stories told from the local black universe, given that their characters are black people, in which they expose their misfortune, beliefs, discriminations and spoliation to which were submitted old slaves and their descendent, practices really common and discriminated in that period. Three stories are described (even though they are not the only ones in the community), we analyze the social-historical context in which they spread, the consequences of the actions described and the contribution that the same bring to the traditional, popular culture and the oral tales as community practice.
description: Comparative Cultural Studies - European and Latin American Perspectives, Vol. 3 No. 6 (2018)
The Best Question
Creators: name: Varzi, Achille C.
Publisher: name: Columbia University
Year: 2001
Subjects: subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Logic

description: Question-answer contexts are prone to self-reference and ungroundedness, as when we ask: "What is your answer to this question?" Or when we respond: "This is the answer to your question." This sort of phenomenon is familiar from the literature on erotetic logic and provides good evidence for Belnap and Steel’s celebrated Hauptsatz: "Ask a foolish question and you get a foolish answer." The trouble is that sometimes our foolishness escapes us. Here is a way of putting the problem, which Ned Markosian calls the “paradox of the question”. An angel shows up at a conference of the world’s leading philosophers and gives them a unique opportunity to ask a question of their choice. The angel comes to them as a messenger from God and will answer their question truthfully—but she will only answer one question. What should the philosophers ask to make the most of their opportunity? Clearly they want to learn something about a truly important and intrinsically interesting subject. But which subject they should address is itself  something they would like to know. After much debating, the proposal of a bright young logician is approved.
A survey of H$_2$O, CO$_2$ and CO ice features towards background stars and low mass YSOs using AKARI
Creators: name: Noble, J. A.
name: Fraser, H. J.
name: Aikawa, Y.
name: Pontoppidan, K. M.
name: Sakon, I.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present near infrared spectroscopic observations of 19 molecular clouds made using the AKARI satellite, and the data reduction pipeline written to analyse those observations. The 2.5 --~5 $μ$m spectra of 30 objects -- 22 field stars behind quiescent molecular clouds and eight low mass YSOs in cores -- were successfully extracted using the pipeline. Those spectra are further analysed to calculate the column densities of key solid phase molecular species, including H$_2$O, CO$_2$, CO, and OCN$^-$. The profile of the H$_2$O ice band is seen to vary across the objects observed and we suggest that the extended red wing may be an evolutionary indicator of both dust and ice mantle properties. The observation of 22 spectra with fluxes as low as $
description: Accepted for publication in ApJ
Keratinocyte cytoskeletal roles in cell sheet engineering
Creators: name: Wei, Qi
name: Reidler, Daniel
name: Shen, Min Ye
name: Huang, Hayden
Publisher: name: Columbia University
Year: 2013
Subjects: Biomedical engineering

description: Background: There is an increasing need to understand cell-cell interactions for cell and tissue engineering purposes, such as optimizing cell sheet constructs, as well as for examining adhesion defect diseases. For cell-sheet engineering, one major obstacle to sheet function is that cell sheets in suspension are fragile and, over time, will contract. While the role of the cytoskeleton in maintaining the structure and adhesion of cells cultured on a rigid substrate is well-characterized, a systematic examination of the role played by different components of the cytoskeleton in regulating cell sheet contraction and cohesion in the absence of a substrate has been lacking. Results: In this study, keratinocytes were cultured until confluent and cell sheets were generated using dispase to remove the influence of the substrate. The effects of disrupting actin, microtubules or intermediate filaments on cell-cell interactions were assessed by measuring cell sheet cohesion and contraction. Keratin intermediate filament disruption caused comparable effects on cell sheet cohesion and contraction, when compared to actin or microtubule disruption. Interfering with actomyosin contraction demonstrated that interfering with cell contraction can also diminish cell cohesion. Conclusions: All components of the cytoskeleton are involved in maintaining cell sheet cohesion and contraction, although not to the same extent. These findings demonstrate that substrate-free cell sheet biomechanical properties are dependent on the integrity of the cytoskeleton network.
title: Trinum Perfectum Abbatis Optomi Honoribus Onomasticis Reverendissimi ... Domini Joannis Evangelistae Ad Quercum Superiorum Abbatis Vigilantissimi; 1758
title: à Subditorum Filiorum DILeCtIssIMo CoetV DVLCIssIMa CharItate Oblatum
titleType: Subtitle
Creators: name: (:Unav)
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2011

description: Erscheinungsjahr nach einem Chronogrammm
Stellar Magnetism and starspots: the implications for exoplanets
Creators: name: Vilela, Conrad
name: Southworth, John
name: del Burgo, Carlos
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Stellar variability induce by starspots can hamper the detection of exoplanets and bias planet property estimations. These features can also be used to study star-planet interactions as well as inferring properties from the underlying stellar dynamo. However, typical techniques, such as ZDI, are not possible for most host-stars. We present a robust method based on spot modelling to map the surface of active star allowing us to statistically study the effects and interactions of stellar magnetism with transiting exoplanets. The method is applied to the active Kepler-9 star where we find small evidence for a possible interaction between planet and stellar magnetosphere which leads to a 2:1 resonance between the spot rotation and orbital period.
description: 4 pages, 1 figure, to be published in the proceedings of IAUS 302: Magnetic Fields Throughout Stellar Evolution
Introducción al número especial en homenaje a Leyda Oquendo Barrios (1940-2008)
Creators: name: Campani, Giovanna
name: Portuondo Cárdenas, Inaury
Publisher: name: Comparative Cultural Studies - European and Latin American Perspectives
Year: 2018

description: Comparative Cultural Studies - European and Latin American Perspectives, Vol. 3 No. 6 (2018)
Reporting of analyses from randomized controlled trials with multiple arms: a systematic review
Creators: name: Ravaud, Philippe
name: Perrodeau, Elodie
name: Boutron, Isabelle
name: Baron, Gabriel
Publisher: name: Columbia University
Year: 2013
Subjects: subject: Statistics
subject: FOS: Mathematics
subject: Medical sciences

description: Background: Multiple-arm randomized trials can be more complex in their design, data analysis, and result reporting than two-arm trials. We conducted a systematic review to assess the reporting of analyses in reports of randomized controlled trials (RCTs) with multiple arms. Methods: The literature in the MEDLINE database was searched for reports of RCTs with multiple arms published in 2009 in the core clinical journals. Two reviewers extracted data using a standardized extraction form. Results: In total, 298 reports were identified. Descriptions of the baseline characteristics and outcomes per group were missing in 45 reports (15.1%) and 48 reports (16.1%), respectively. More than half of the articles (n = 171, 57.4%) reported that a planned global test comparison was used (that is, assessment of the global differences between all groups), but 67 (39.2%) of these 171 articles did not report details of the planned analysis. Of the 116 articles reporting a global comparison test, 12 (10.3%) did not report the analysis as planned. In all, 60% of publications (n = 180) described planned pairwise test comparisons (that is, assessment of the difference between two groups), but 20 of these 180 articles (11.1%) did not report the pairwise test comparisons. Of the 204 articles reporting pairwise test comparisons, the comparisons were not planned for 44 (21.6%) of them. Less than half the reports (n = 137; 46%) provided baseline and outcome data per arm and reported the analysis as planned. Conclusions: Our findings highlight discrepancies between the planning and reporting of analyses in reports of multiple-arm trials.
Proceedings 10th International Workshop On User Interfaces for Theorem Provers
Creators: name: Kaliszyk, Cezary
name: Lüth, Christoph
Publisher: name: arXiv
Year: 2013
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Human-Computer Interaction (cs.HC)
subject: Mathematical Software (cs.MS)
subject: FOS: Computer and information sciences

description: This EPTCS volume collects the post-proceedings of the 10th International Workshop On User Interfaces for Theorem Provers (UITP 2012), held as part of the Conferences on Intelligent Computer Mathematics (CICM 2012) in Bremen on July 11th 2012. The UITP workshop series aims at bringing together reasearchers interested in designing, developing and evaluating interfaces for interactive proof systems, such as theorem provers, formal method tools, and other tools manipulating and presenting mathematical formulae. Started in 1995, it can look back on seventeen years of history by now. The papers in the present volume give a good indication of the range of questions currently addressed in the UITP community; this ranges from interface design (Windsteiger; Dunchev et al) to using technologies such as machine learning to assist the user (Komendantskaya et al). The web features prominently (Tankink), and new technology necessitates changes right down to the very basic modes of interaction (Wenzel) - the old REPL (read, evaluate, print, loop) mode of interaction can not take advantage of modern technology, such as the web and multi-core machines.
María Soledad Balsas, Televisión y participación política transnacionales. Las audiencias de televisión italiana en Buenos Aires. Editorial Prometeo, Buenos Aires, 2018, 260 páginas
Creators: name: Melella, Cecilia Eleonora
Publisher: name: Comparative Cultural Studies - European and Latin American Perspectives
Year: 2018

description: Comparative Cultural Studies - European and Latin American Perspectives, Vol. 3 No. 5 (2018)
Padilla, Beatriz; Azevedo, Joana; França, Thais (organizadoras) (2017), Migrações Internacionais e Políticas Públicas Portuguesas. Lisboa, Mundos Sociais
Creators: name: Ribas Vieira, Adriane
Publisher: name: Comparative Cultural Studies - European and Latin American Perspectives
Year: 2018

description: Comparative Cultural Studies - European and Latin American Perspectives, Vol. 3 No. 5 (2018)
Tuning exciton and biexciton transition energies and fine structure splitting through hydrostatic pressure in single InGaAs quantum dots
Creators: name: Wu, Xuefei
name: Wei, Hai
name: Dou, Xiuming
name: Ding, Kun
name: Yu, Ying
name: Ni, Haiqiao
name: Niu, Zhichuan
name: Ji, Yang
name: Li, Shushen
name: Jiang, Desheng
name: Guo, Guangcan
name: He, Lixin
name: Sun, Baoquan
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We demonstrate that the exciton and biexciton emission energies as well as exciton fine structure splitting (FSS) in single (In,Ga)As/GaAs quantum dots (QDs) can be efficiently tuned using hydrostatic pressure in situ in an optical cryostat at up to 4.4 GPa. The maximum exciton emission energy shift was up to 380 meV, and the FSS was up to 180 $μ$eV. We successfully produced a biexciton antibinding-binding transition in QDs, which is the key experimental condition that generates color- and polarization-indistinguishable photon pairs from the cascade of biexciton emissions and that generates entangled photons via a time-reordering scheme. We perform atomistic pseudopotential calculations on realistic (In,Ga)As/GaAs QDs to understand the physical mechanism underlying the hydrostatic pressure-induced effects.
Indian Sign Language Translation System Using Deep Convolutional Neural Network
Creators: name: Solaris Publication
Publisher: name: figshare
Year: 2020
Subjects: Computer Engineering

description: The deaf and mute individuals are a very important part of our society. Due to lack of aware-ness of sign languages among the general population, these individuals are often isolated. An effective solution for breaking this barrier is needed. In this paper we have discussed the implementation of a sign language translator by using Convolutional Neural Network (CNN). A few preprocessing techniques such as Skin Masking and Canny Edge Detection is applied. Finally, the model of Convolutional Neural Network is applied by taking into account its recent advances for better detection of hand movements and classification. It has an excellent performance in machine learning problems.
Correlation of tumor-associated macrophages and clinicopathological factors in Wilms tumor
Creators: name: Liou, Peter
name: Bader, Leah
name: Wang, Antai
name: Yamashiro, Darrell J.
name: Kandel, Jessica
Publisher: name: Columbia University
Year: 2013
Subjects: Oncology
Surgery

description: Background/purpose: Despite high long-term survival rates in patients with Wilms tumor, there is a need to develop better prognostic biomarkers in order to maximize cure while avoiding treatment-associated morbidities. Tumor-associated macrophages have been recently associated with poorer prognosis and increased disease progression in a number of adult cancers. We investigated the relationship between macrophages and clinicopathological fators in this pediatric solid tumor. Methods: Tissue microarray sections of 124 Wilms tumor cases obtained from the Cooperative Human Tissue Network were stained with CD68, a macrophage marker using standard immunohistochemical techniques and quantified using digital image processing techniques. Macrophage densities were correlated by tumor stage, and survival analyses were conducted with available clinical data. Immunohistochemistry was performed on 25 additional Wilms tumor cases obtained from the tumor bank at Columbia University Medical Center and correlated with presence of tumor microvascular invasion. Results: Mean macrophage count densities in stage IV tumors were significantly greater than densities in stage I and III tumors (p=.021, .036). Although the overall and disease-free survival did not differ between high and low macrophage presence groups across all stages, increased macrophage presence was associated with decreased disease-free survival in patients with stage II tumors (p=0.035). Increased macrophage presence may have also correlated with decreased disease-free survival in stage IV patients, but the sample size was too small to allow detection of this difference with significance (p=0.575). Increased macrophage presence was associated with tumor microvascular invasion (p=0.0004). Conclusion: Our results suggest that macrophage recruitment may be associated with disease progression in Wilms tumor. Quantitation of macrophage presence may therefore be a useful adjunct in refining staging algorithms for patients with stage II Wilms tumor. Such data might be useful in the effort to reduce the risk of adverse effects associated with under- or overtreatment of this neoplasm.
Asignación Universal por Hijo para la Protección Social: aproximación al enfoque de derechos y su concepción de los inmigrantes en Argentina
Creators: name: Guzzo, Giuliana
name: Navarro Sanz, Gonzalo Gabriel
Publisher: name: Comparative Cultural Studies - European and Latin American Perspectives
Year: 2018

description: This article has the purpose to analyze and reflect the relationship between AUHPS and the migration phenomenon in Argentina. Concretely, it refers that although there was a social and political progress in the country, of respect and recognition to rights of the sons of parents of workers in infomality. This was not the same with Immigrant workers in informal and their families. In this sense, this article tries to find and show meanings and representations of immigrant workers in Argentina, especially Bolivian women who work in Guaymallén, Mendoza State and because of their labor situation they are directly and indirectly connected with the social and political issues.
description: Comparative Cultural Studies - European and Latin American Perspectives, Vol. 3 No. 5 (2018)
Procesos de diferenciación de personas de nacionalidad extranjera desde la normativa sobre empleo de hogar. El caso de las empleadas de hogar de nacionalidad extranjera extracomunitaria en España
Creators: name: López Fernández, Rosalía
name: Maroto Blanco, José Manuel
Publisher: name: Comparative Cultural Studies - European and Latin American Perspectives
Year: 2018

description: The aim of this text is to analyse the differentiation processes and mechanisms of foreign population, specifically migrant women of non - European Union foreign nationality, which are produced by the legislation on domestic employment. From the life stories of fifteen women it will be addressed how the practices and social representations generated in the legislation itself build ethnically and occupationally degraded subjects. These women are represented as a feminized, homogenous and as an inferiorized collective, whilst in the area of domestic work converge different axis of oppression that are not amended by legislation. This analysis will show that although many of these differentiation processes are interconnected with elements of a structural nature, the naturalization of inequality is elaborated from concrete practices that are not only exhausted in the normative.
description: Comparative Cultural Studies - European and Latin American Perspectives, Vol. 3 No. 5 (2018)
Pinpointing beta adrenergic receptor in ageing pathophysiology: victim or executioner? Evidence from crime scenes
Creators: name: Santulli, Gaetano
name: Iaccarino, Guido
Publisher: name: Columbia University
Year: 2013
Subjects: Biophysics
Cytology

description: G protein-coupled receptors (GPCRs) play a key role in cellular communication, allowing human cells to sense external cues or to talk each other through hormones or neurotransmitters. Research in this field has been recently awarded with the Nobel Prize in chemistry to Robert J. Lefkowitz and Brian K. Kobilka, for their pioneering work on beta adrenergic receptors (βARs), a prototype GPCR. Such receptors, and β2AR in particular, which is extensively distributed throughout the body, are involved in a number of pathophysiological processes. Moreover, a large amount of studies has demonstrated their participation in ageing process. Reciprocally, age-related changes in regulation of receptor responses have been observed in numerous tissues and include modifications of βAR responses. Impaired sympathetic nervous system function has been indeed evoked as at least a partial explanation for several modifications that occur with ageing. This article represents an updated presentation of the current knowledge in the field, summarizing in a systematic way the major findings of research on ageing in several organs and tissues (crime scenes) expressing βARs: heart, vessels, skeletal muscle, respiratory system, brain, immune system, pancreatic islets, liver, kidney and bone.
ҚОРАҚАЛПОҒИСТОНДА 1941-1945 ЙИЛЛАРДА КУТУБХОНАЛАР ИШИ ҲОЛАТИ
Creators: name: Утениязова, Болганай
Publisher: name: Zenodo
Year: 2023

description: Мақола Қорақалпоғистондаватандорлик уруш йилларда кутубхоначиликнинг шаклланиши ва ривожланиш тарихига бағишланган. Кутубхоналарни мафкуравий ишларнинг кўчли таянч нуқтасига айлантириш мақсадини кўзлаган Совет-партия органларининг бу борадаги қарорларининг роли қайд этилган. Қорақалпоғистон уруш шароитида кутубхоначилик ишининг аҳволи кўрсатилган.
From scale properties of physical amplitudes to a predictive formulation of the Nambu-Jona-Lasinio model
Creators: name: Battistel, O. A.
name: Dallabona, G.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The predictive power of the NJL model is considered in the light of a novel strategy to handle the divergences typical of perturbative calculations. The referred calculational strategy eliminates unphysical dependencies on the arbitrary choices for the routing of internal momenta and symmetry violating terms. In the present work we extend a previous one on the same issue by including vector interactions and performing the discussion in a more general context: it is considered the role of scale arbitrariness for the consistency of the calculations. We show that the imposition of arbitrary scale independence for the consistent regularized amplitudes lead to additional properties for the irreducible divergent objects. These properties allow us to parametrize the remaining freedom in terms of a unique constant where resides all the arbitrariness involved. By searching for the best value for the arbitrary parameter we find a critical condition for the existence of an acceptable physical value for the dynamically generated quark mass. Such critical condition fixes the remaining arbitrariness turning the NJL into a predictive model in the sense that its phenomenological consequences do not depend on possible choices made in intermediary steps. Numerical results are obtained for physical quantities like the vector and axial-vector masses and their coupling constants as genuine predictions.
“I am free”: Gender statements and the empowerment pedagogies for refugee women in Brazil
Creators: name: Carvalho Ribeiro, Jullyane
Publisher: name: Comparative Cultural Studies - European and Latin American Perspectives
Year: 2018

description: In this article, I analyze a set of gender statements that, intertwined with the category of refuge, constitutes a specific narrative articulated by the international organizations integrated to the transnational human rights regimes. I take the United Nations (UN) project Empowering Refugees as a reference to introduce gender narratives that will largely direct the asylum policies in the Brazilian context. I also discuss the effects of these actions on the lives of two women who engaged in the project in the city of Sao Paulo: Samira, example of empowerment presented publicly; and Jana, also a participant in the project, but who did not become a public voice for its results. My main argument is that projects aimed at “refugee women” headed by international agencies are promoting an empowerment pedagogy based on concepts such as autonomy and freedom, which does not necessarily favor women who are the targets of their actions.
description: Comparative Cultural Studies - European and Latin American Perspectives, Vol. 3 No. 5 (2018)
"d13-058.table4_w_allH1_v1.txt" of "Elastic and Proton-Dissociative Photoproduction of J/psi Mesons at HERA"
Creators: name: H1 Collaboration
Publisher: name: HEPData
Year: 2017

description: 1: Table 4 data with full error breakdown
description: DESY-HERA. Cross sections for elastic and proton-dissociative photoproduction of J/psi mesons are measured with the H1 detector in positron-proton collisions at HERA. The data were collected at -of-mass energies sqrt{s} approx 318 GeV and sqrt{s} approx 225 GeV, corresponding to integrated luminosities of L = 130 pb^{-1} and L = 10.8 pb^{-1}, respectively. The cross sections are measured as a function of the photon-proton centre-of-mass energy in the range 25< Wgp < 110 GeV. Differential cross sections mathrm{d}sigma / mathrm{d}t where the squared four-momentum transfer at the proton vertex, are measured in the range 0t| < 1.2 , gevsq the elastic process and 0t| < 8 , gevsq proton dissociation. The results are compared to other measurements. The Wgp 0dependences are parametrised using phenomenological fits.