cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
EPOS Gender Equality Plan
Creators: name: Maracchia, Giovanna
name: Tanlongo, Federica
name: Bailo, Daniele
name: Piras, Diana
name: Freda, Carmela
name: Sangianantoni, Agata
name: Mercurio, Daniela
name: Angioni, Barbara
Publisher: name: Zenodo
Year: 2023
Subjects: subject: Gender equality

description: The document presents the EPOS Gender Equality Plan (GEP).

The EPOS ERIC GEP relies on the following goals as recommended in the Horizon Europe guidance on gender equality plans:

Goal 1: Work-life balance and organisational culture.

Goal 2: Gender balance in leadership, decision-making and executive bodies.

Goal 3: Gender equality in recruitment and career progression.

Goal 4: Integrating the gender dimension into research content.

Goal 5: Measures against gender-based violence, including sexual harassment
Additional file 4 of The evolution of relapse of adult T cell acute lymphoblastic leukemia
Creators: name: Sentís, Inés
name: Gonzalez, Santiago
name: Genescà, Eulalia
name: García-Hernández, Violeta
name: Muiños, Ferran
name: Gonzalez, Celia
name: López-Arribillaga, Erika
name: Gonzalez, Jessica
name: Lierni Fernandez-Ibarrondo
name: Mularoni, Loris
name: Lluís Espinosa
name: Bellosillo, Beatriz
name: Josep-Maria Ribera
name: Bigas, Anna
name: Gonzalez-Perez, Abel
name: Lopez-Bigas, Nuria
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 4. Review history.
Resistive relativistic MHD simulations of astrophysical jets
Creators: name: Mattia, Giancarlo
name: Del Zanna, Luca
name: Bugli, Matteo
name: Pavan, Andrea
name: Ciolfi, Riccardo
name: Bodo, Gianluigi
name: Mignone, Andrea
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Aims. The main goal of the present paper is to provide the first systematic numerical study of the propagation of astrophysical relativistic jets, in the context of high-resolution shock-capturing resistive relativistic magnetohydrodynamics (RRMHD) simulations. We aim at investigating different values and models for the plasma resistivity coefficient, and at assessing their impact on the level of turbulence, the formation of current sheets and reconnection plasmoids, the electromagnetic energy content, and the dissipated power. Methods. We use the PLUTO code for simulations and we assume an axisymmetric setup for jets, endowed with both poloidal and toroidal magnetic fields, and propagating in a uniform magnetized medium. The gas is assumed to be characterized by a realistic Synge-like equation of state (Taub equation), appropriate for such type of astrophysical jets. The Taub equation is combined here for the first time with the Implicit-Explicit Runge-Kutta time-stepping procedure, as required in RRMHD simulations. Results. The main result is that turbulence is clearly suppressed for the highest values of resistivity (low Lundquist numbers), current sheets are broader, and plasmoids are barely present, while for low values of resistivity results are very similar to ideal runs, where dissipation is purely numerical. We find that recipes employing a variable resistivity based on the advection of a jet tracer or on the assumption of a uniform Lundquist number improve on the use of a constant coefficient and are probably more realistic, preserving the development of turbulence and of sharp current sheets, possible sites for the acceleration of the non-thermal particles producing the observed high-energy emission.
description: 17 pages, 16 figures, accepted for publication in A&A
Scattering of emission lines in galaxy cluster cores: measuring electron temperature
Creators: name: Khedekar, S.
name: Churazov, E.
name: Sazonov, S.
name: Sunyaev, R.
name: Emsellem, E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The central galaxies of some clusters can be strong emitters in the Ly$α$ and H$α$ lines. This emission may arise either from the cool/warm gas located in the cool core of the cluster or from the bright AGN within the central galaxy. The luminosities of such lines can be as high as $10^{42} - 10^{44}$ erg/s. This emission originating from the core of the cluster will get Thomson scattered by hot electrons of the intra-cluster medium (ICM) with an optical depth $\sim$ 0.01 giving rise to very broad ($Δλ/ λ\sim$ 15%) features in the scattered spectrum. We discuss the possibility of measuring the electron density and temperature using information on the flux and width of the highly broadened line features.
description: 9 pages, 5 figures, accepted in MNRAS
Additional file 3 of The evolution of relapse of adult T cell acute lymphoblastic leukemia
Creators: name: Sentís, Inés
name: Gonzalez, Santiago
name: Genescà, Eulalia
name: García-Hernández, Violeta
name: Muiños, Ferran
name: Gonzalez, Celia
name: López-Arribillaga, Erika
name: Gonzalez, Jessica
name: Lierni Fernandez-Ibarrondo
name: Mularoni, Loris
name: Lluís Espinosa
name: Bellosillo, Beatriz
name: Josep-Maria Ribera
name: Bigas, Anna
name: Gonzalez-Perez, Abel
name: Lopez-Bigas, Nuria
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 3. Additional methods. Some of the filtering steps have been extended for clarification in this file.
Wave-Packet Effects: A Solution for Isospin Anomalies in Vector-Meson Decay
Creators: name: Ishikawa, Kenzo
name: Jinnouchi, Osamu
name: Nishiwaki, Kenji
name: Oda, Kin-ya
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: There is a long-standing anomaly in the ratio of the decay width for $ψ(3770)\to D^0\overline{D^0}$ to that for $ψ(3770)\to D^+D^-$ at the level of $9.5\,σ$. A similar anomaly exists for the ratio of $ϕ(1020)\to K_\text{L}^0K_\text{S}^0$ to $ϕ(1020)\to K^+K^-$ at $2.1\,σ$. In this study, we reassess the anomaly through the lens of Gaussian wave-packet formalism. Our comprehensive calculations include the localization of the overlap of the wave packets near the mass thresholds as well as the composite nature of the initial-state vector mesons. The results align within $\sim 1 σ$ confidence level with the Particle Data Group's central values for a physically reasonable value of the form-factor parameter, indicating a resolution to these anomalies. We also check the deviation of a wave-packet resonance from the Briet-Wigner shape and find that wide ranges of the wave-packet size are consistent with the experimental data.
description: 50 pages, 16 figures; footnote 23 added, minor typos corrected, accepted for publication in EPJC
Additional file 2 of The evolution of relapse of adult T cell acute lymphoblastic leukemia
Creators: name: Sentís, Inés
name: Gonzalez, Santiago
name: Genescà, Eulalia
name: García-Hernández, Violeta
name: Muiños, Ferran
name: Gonzalez, Celia
name: López-Arribillaga, Erika
name: Gonzalez, Jessica
name: Lierni Fernandez-Ibarrondo
name: Mularoni, Loris
name: Lluís Espinosa
name: Bellosillo, Beatriz
name: Josep-Maria Ribera
name: Bigas, Anna
name: Gonzalez-Perez, Abel
name: Lopez-Bigas, Nuria
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 2. Additional figures. This file presents all supplementary figures referenced in the main text.
ILCAS: Imitation Learning-Based Configuration-Adaptive Streaming for Live Video Analytics with Cross-Camera Collaboration
Creators: name: Wu, Duo
name: Zhang, Dayou
name: Zhang, Miao
name: Zhang, Ruoyu
name: Wang, Fangxin
name: Cui, Shuguang
Publisher: name: arXiv
Year: 2023
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Machine Learning (cs.LG)
subject: Multimedia (cs.MM)
subject: FOS: Computer and information sciences

description: The high-accuracy and resource-intensive deep neural networks (DNNs) have been widely adopted by live video analytics (VA), where camera videos are streamed over the network to resource-rich edge/cloud servers for DNN inference. Common video encoding configurations (e.g., resolution and frame rate) have been identified with significant impacts on striking the balance between bandwidth consumption and inference accuracy and therefore their adaption scheme has been a focus of optimization. However, previous profiling-based solutions suffer from high profiling cost, while existing deep reinforcement learning (DRL) based solutions may achieve poor performance due to the usage of fixed reward function for training the agent, which fails to craft the application goals in various scenarios. In this paper, we propose ILCAS, the first imitation learning (IL) based configuration-adaptive VA streaming system. Unlike DRL-based solutions, ILCAS trains the agent with demonstrations collected from the expert which is designed as an offline optimal policy that solves the configuration adaption problem through dynamic programming. To tackle the challenge of video content dynamics, ILCAS derives motion feature maps based on motion vectors which allow ILCAS to visually ``perceive'' video content changes. Moreover, ILCAS incorporates a cross-camera collaboration scheme to exploit the spatio-temporal correlations of cameras for more proper configuration selection. Extensive experiments confirm the superiority of ILCAS compared with state-of-the-art solutions, with 2-20.9% improvement of mean accuracy and 19.9-85.3% reduction of chunk upload lag.
description: This article has been accepted for publication in IEEE Transactions on Mobile Computing. Citation information: DOI 10.1109/TMC.2023.3327097
title: Mid-gestation Angiogenic Biomarker Levels are Increased in Women at High Risk for Preeclampsia
Creators: name: Moore Simas, Tiffany A.
name: Crawford, Sybil L.
name: Bathgate, Susie
name: Yang, Jing
name: Robidoux, Laura
name: Moore, Melissa J.
name: Maynard, Sharon E.
Publisher: name: eScholarship@UMMS
Year: 2012

description: Background: Pre-pregnancy hypertension and diabetes mellitus, multiple gestations, prior preeclampsia, are significant risk factors for preeclampsia. Whether altered maternal levels of angiogenic factors contribute to increased preeclampsia risk in these conditions is unknown. Our objective was to compare maternal serum angiogenic biomarker levels in women with major risk factors for preeclampsia and healthy controls.

Methods: Women presenting for prenatal care were enrolled if they had one of the following preeclampsia risk factors: pre-pregnancy hypertension and/or diabetes mellitus, nulliparity with pre-pregnancy BMI>30, multiple gestations, or prior preeclampsia. Healthy control pregnancies without these risk factors were enrolled for comparison. Maternal serum samples were collected at 3 pre-specified gestational windows between 23 and 36 weeks gestation. sFlt1, sEng, and PlGF were measured by ELISA. The (sFlt1+sEng):PlGF ratio was calculated and compared for each risk group at each gestational window.

Results: Gestational patterns of angiogenic biomarkers differed in high-risk groups vs. healthy control subjects. The angiogenic ratio (sFlt1+sEng):PlGF was higher for all high risk groups except obesity/nulliparity as compared with healthy control subjects after 28 weeks gestation. Biomarker ratio levels were highest in subjects with MG and prior PE, and differences from the health control group became more pronounced as gestation progressed. Women with hypertension/diabetes had more subtle differences as compared with healthy control subjects.

Conclusion: Women with preeclampsia risk factors had higher angiogenic ratios compared with healthy control women. This study illuminates the interplay between risk factors and placental angiogenic biomarkers in the pathogenesis of preeclampsia.
Materialität: Wie die Sinne Sinn in Bewegung setzen
Creators: name: Frers, Lars
Publisher: name: Edition Topoi
Year: 2018

description: In diesem Beitrag steht die Begegnung mit dem Objekt im Zentrum. Im emphatischen Sinne verstanden, bringt eine Begegnung immer Änderungen mit sich, die alle an der Begegnung beteiligten Parteien betreffen. Die Begegnung wird in ihrer Sinnlichkeit aus der Bewegung heraus gedacht. Das heißt zum einen, dass der Bewegung ein gewisser Sinn, also eine gewisse Richtung oder Ausrichtung innewohnt. Wie ändert sich dieser Sinn in der Begegnung? Zum anderen ist die verkörperlichte Sinnlichkeit relevant: Wie verknüpfen sich Dinge, Körper und Sinne? Beide Fragen werden in einen zeitlichen Vollzug eingeordnet, vom Weg zum Objekt und seinem Ort, über eine Phase des Kontakts bis zum mehr oder weniger offenen Danach. Zum Abschluss werden die Rolle von Wiederholung und Abwesenheit thematisiert.
title: Circulating microRNAs are associated with Paroxysmal or Persistent Atrial Fibrillation
Creators: name: McManus, David D.
name: Ward, Jeanine
name: Shaikh, Amir Y.
name: Jaggi, Khushleen
name: Ambros, Victor R.
name: Freedman, Jane
name: Keaney Jr., John F.
Publisher: name: eScholarship@UMMS
Year: 2012

description: Introduction: Novel methods of identifying individuals at risk for atrial fibrillation (AF) are needed. MicroRNAs (MiRNAs) regulate gene expression in a number of cardiovascular diseases, including AF. It is unknown, however, if key circulating, cardiac-specific miRNAs differ between individuals with paroxysmal or persistent AF and those in sinus rhythm.

Methods: 17 individuals with a history of AF were recruited prior to catheter ablation. 24 hospitalized patients in normal sinus rhythm and no history of AF comprised the control group. 94 plasma miRNAs were selected based on a priori associations with processes implicated in AF for evaluation using the TaqMan miRNA expression profiling system.

Results: We found that miRNA expression differed by at least 2-fold for 14 miRNAs, including several previously implicated in cardiovascular remodeling and disease (Figure 1). Levels of miR-7, miR-208, and miR-302b were statistically significantly up- or down-regulated in AF patients relative to controls (p<0.05) and levels of miR-218 differed by greater than 20-fold (p=0.095).

Application: Although power was limited by the modest sample size, these data support the rationale for using circulating miRNA as AF biomarkers. Moreover, since miRNA can modulate disease pathways, miRNA-based therapeutics would theoretically enable targeting of novel gene regulatory pathways implicated in AF in a unique and powerful manner.

Next Steps/ Future: Further investigations involving well-characterized, large samples from longitudinal studies with standardized miRNA assessment and evaluation for AF are required to validate the observed associations.
Dinge erkennen
Creators: name: Hahn, Hans Peter
Publisher: name: Edition Topoi
Year: 2018

description: Materielle Dinge erscheinen in vielen Wissenspraktiken als die sichere Grundlage der Erkenntnis. Die Ausweitung der Wissensfelder im 19. Jahrhundert brachte es mit sich, dass auch in der Ethnologie die materiellen Dinge als erste und sicherste Erkenntnismöglichkeit fremder Kulturen galten. Die Betrach­tung der Dinge und das Nebeneinanderstellen von Artefakten führte schnell zur Bildung neuer weltumspannender Kulturtheorien. Die Dinge wurden nicht um ihrer selbst betrachtet, sondern als Elemente eines übergeordneten ideellen Systems. Erst in der Zeit nach 1950 haben poststrukturalistische Ansätze die Behauptung solcher Evidenzen hinterfragt. Seit dieser Zeit gilt die Einsicht, dass Dinge mehrere Bedeutungen haben, und ihre Rolle abhängig ist von der Form der Einbettung in die jeweilige Kultur. Dinge sind mithin nicht einfach das Spiegelbild einer Gesellschaft, sondern wirken an deren Gestaltung und Weiterentwicklung mit.
title: Use of whole plant Artemisia annua L. as an antimalarial therapy
Creators: name: Mostafa, Elfawal
name: Towler, Melissa J.
name: Gazzinelli, Ricardo T.
name: Golenbock, Douglas T.
name: Weathers, Pamela J.
name: Rich, Stephen M.
Publisher: name: eScholarship@UMMS
Year: 2012

description: Anti-malarial drugs are primary weapons for reducing Plasmodium transmission in human populations. Successful drugs have been highly efficacious and inexpensive to synthetically manufacture. Emergence of resistant parasites reduces the lifespan of each drug that is developed and deployed. Currently, the most effective anti-malarial is artemisinin (AN), which is extracted from the leaves of Artemisia annua. Because of its poor pharmacokinetic properties and prudent efforts to curtail emergence of resistance, AN is prescribed only in combination with other anti-malarials composing an Artemisinin Combination Therapy (ACT). Low yield in the plant and the added cost of secondary anti-malarials in the ACT, make AN in the developing world a costly treatment. Here we show that dried leaves of A. annua administered orally are more effective at killing malaria parasites than a comparable dose of purified drug in a rodent malaria model (P. chabaudi). A single dose of whole plant (WP) A. annua containing 24 mg/kg AN clears 99% of parasites, where a comparable dose of pure drug has half that effect. This is consistent with findings that blood levels of AN are 40 times greater in mice receiving WP versus those given pure drug. We hypothesize that in addition to increasing bioavailability of AN, administration of WP alone may constitute a combination therapy because it contains other anti-malarial compounds that have been shown to synergize with AN. Inexpensive, efficacious, and resilient treatment for malaria based upon WP A. annua that can be grown and processed locally would be an effective addition to the global effort to reduce malaria morbidity and mortality.
Sammlungen und das kulturhistorische Präparat
Creators: name: König, Gudrun M.
Publisher: name: Edition Topoi
Year: 2018

description: Neben dem Sammeln und Bewahren bringen spezifische Benennungspraktiken, Klassifikationen, Bild-Text-Bezüge und Ordnungsoperationen das Museumsobjekt hervor. Mit Bezug auf Hans-Jörg Rheinbergers “Epistemologica” kann, so die These, auch im Kontext kulturhistorischer Sammlungen von Objekten als Präparaten gesprochen und das Museumsobjekt als Produkt von Praktiken verstan­den werden. Die Konzipierung kulturhistorischer Museumsdinge als Präparate zielt darauf, die Dimen­sionen der Aufbereitung und Zurichtung systematisch zu fassen, denn museale Handhabungen der natur- und kulturhistorischen Objekte weisen auf parallele Praktiken des Deponierens, Konser­vierens und Visualisierens hin. Unterschiede und disziplinäre Spezifika werden damit nicht ignoriert, sondern zum Untersuchungsgegenstand gemacht.
Additional file 1 of Impact of a computerized decision support tool deployed in two intensive care units on acute kidney injury progression and guideline compliance: a prospective observational study
Creators: name: Bourdeaux, Christopher
name: Ghosh, Erina
name: Atallah, Louis
name: Palanisamy, Krishnamoorthy
name: Payaal Patel
name: Thomas, Matthew
name: Gould, Timothy
name: Warburton, John
name: Rivers, Jon
name: Hadfield, John
Publisher: name: figshare
Year: 2020
Subjects: subject: Cell Biology
subject: Neuroscience
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Additional file containing table and figures providing additional information as referenced in the text.
title: Incidence rates of ICU complications in moderate-severe traumatic brain injury (TBI)
Creators: name: Muehlschlegel, Susanne
name: Carandang, Raphael A.
name: Ouillette, Cynthia
name: Hall, Wiley R.
name: Anderson Jr., Frederick A.
name: Goldberg, Robert J.
Publisher: name: eScholarship@UMMS
Year: 2012

description: Retrospective studies suggest that non-neurologic organ failure may contribute to 2/3 of all deaths after TBI, but the actual incidence rates of specific intensive care unit (ICU) complications in moderate-severe TBI are not known. In a prospective observational cohort study of consecutive TBI patients from a single Level I trauma center (UMASS) over the period 11/2009 – 2/2012, we identified the ten most common medical complications after ICU admission according to strict pre-specified criteria in 170 moderate-severe TBI patients. The mean age of the study sample was 51 years, 72% were men, and the median GCS and injury severity scores were 4 and 29, respectively. Incidence rates of the ten most common medical complications in the ICU were: hyperglycemia (75%), fever (62%), systemic inflammatory response syndrome (38%), cardiac complications (36%), hypotension requiring vasopressors (35%), pneumonia (any type [34%]); sepsis (33%), anemia requiring transfusion (31%), other pulmonary complications (ARDS, pulmonary edema [26%]), and hyponatremia (sodium ≤134mEq/L; [23%]). Medical complications in moderate-severe TBI are very common, and their association with important patient outcomes should be further investigated. Specific medical complications may pose attractive modifiable treatment targets to improve the outcome of moderate-severe TBI patients.
Additional file 2 of Use of PROMIS® to screen for depression in children with arthritis
Creators: name: Yufan Yan
name: Rychlik, Karen L.
name: Rosenman, Marc B.
name: Miller, Michael L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2 Appendix B. PROMIS Pediatric Profile Scoring Manual.
Postkoloniale Objektepistemologien? Homi Bhabhas Konzepte in archäologischen Forschungen – ein Überblick
Creators: name: Beck, Tina
Publisher: name: Edition Topoi
Year: 2018

description: Im Rahmen des Artikels wird der Frage nachgegangen, inwiefern die postkolonialen Konzepte von Homi Bhabha vor allem zu Hybridität, aber auch zum Dritten Raum und Mimikry im Rahmen archäo­logischer Fragestellungen bzw. im Hinblick auf das archäologische Material diskutiert und übersetzt wird. Hierbei lassen sich fünf unterschiedliche Ansätze in archäologischen Arbeiten unter­scheiden: (1) Diskussion von Bhabhas Konzepten und Übersetzung auf archäologisches Material; (2) Diskussion von Bhabhas Konzepten, aber Anwendung anderer Theorien auf das archäologische Material; (3) Verweis auf Bhabhas Konzepte, ohne Anwendung auf das archäologische Material; (4) Aktualisierung eines traditionellen Interpretationsansatzes der kulturellen Vermischung mit Bhabha sowie (5) Über­setzung des Hybriditätskonzeptes mittels eines neu definierten Hybriditätsbegriffs in der Archäologie.
VLBI Observations of H2O Maser Annual Parallax and Proper Motion in IRAS 20143+3634: Reflection on the Galactic Constants
Creators: name: Burns, Ross A.
name: Yamaguchi, Yoshiyuki
name: Handa, Toshihiro
name: Omodaka, Toshihiro
name: Nagayama, Takumi
name: Nakagawa, Akiharu
name: Hayashi, Masahiko
name: Kamezaki, Tatsuya
name: Chibueze, James O.
name: Shizugami, Makoto
name: Nakano, Makoto
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We report the results of VLBI observations of H$_{2}$O masers in the IRAS 20143+3634 star forming region using VERA (VLBI Exploration of Radio Astronomy). By tracking masers for a period of over two years we measured a trigonometric parallax of $π= 0.367 \pm 0.037$ mas, corresponding to a source distance of $D = 2.72 ^{+0.31}_{-0.25}$ kpc and placing it in the Local spiral arm. Our trigonometric distance is just 60% of the previous estimation based on radial velocity, significantly impacting the astrophysics of the source. We measured proper motions of $-2.99 \pm 0.16$ mas yr$^{-1}$ and $-4.37 \pm 0.43$ mas yr$^{-1}$ in R.A. and Decl. respectively, which were used to estimate the peculiar motion of the source as $(U_{s},V_{s},W_{s}) = (-0.9 \pm 2.9, -8.5 \pm 1.6, +8.0 \pm 4.3)$ km s$^{-1}$ for $R_0=8$ kpc and $Θ_0=221$ km s$^{-1}$, and $(U_{s},V_{s},W_{s}) = (-1.0 \pm 2.9, -9.3 \pm 1.5, +8.0 \pm 4.3)$ km s$^{-1}$ for $R_0=8.5$ kpc and $Θ_0=235$ km s$^{-1}$. IRAS 20143+3634 was found to be located near the tangent point in the Cygnus direction. Using our observations we derived the angular velocity of Galactic rotation of the local standard of rest (LSR), $Ω_{0} = 27.3 \pm 1.6$ km s$^{-1}$ kpc$^{-1}$, which is consistent with previous values derived using VLBI astrometry of SFRs at the tangent points and Solar circle. It is higher than the value recommended by the IAU of $Ω_{0} = 25.9$ km s$^{-1}$ kpc$^{-1}$ which was calculated using the Galactocentric distance of the Sun and circular velocity of the LSR.
description: Intended for PASJ VERA special issue Updated version: V2: Corrected typos Removed incorrect phrase regarding the evolutionary stage of IRAS20143, in the conclusions, that had remained in the paper since a far earlier draft version V3: Update email address
Regularized $M$-estimators of scatter matrix
Creators: name: Ollila, Esa
name: Tyler, David E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Applications (stat.AP)
subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: In this paper, a general class of regularized $M$-estimators of scatter matrix are proposed which are suitable also for low or insufficient sample support (small $n$ and large $p$) problems. The considered class constitutes a natural generalization of $M$-estimators of scatter matrix (Maronna, 1976) and are defined as a solution to a penalized $M$-estimation cost function that depend on a pair $(α,β)$ of regularization parameters. We derive general conditions for uniqueness of the solution using concept of geodesic convexity. Since these conditions do not include Tyler's $M$-estimator, necessary and sufficient conditions for uniqueness of the penalized Tyler's cost function are established separately. For the regularized Tyler's $M$-estimator, we also derive a simple, closed form and data dependent solution for choosing the regularization parameter based on shape matrix matching in the mean squared sense. An iterative algorithm that converges to the solution of the regularized $M$-estimating equation is also provided. Finally, some simulations studies illustrate the improved accuracy of the proposed regularized $M$-estimators of scatter compared to their non-regularized counterparts in low sample support problems. An example of radar detection using normalized matched filter (NMF) illustrate that an adaptive NMF detector based on regularized $M$-estimators are able to maintain accurately the preset CFAR level and at at the same time provide similar probability of detection as the (theoretical) NMF detector.
description: Submitted to IEEE Transactions on Signal Processing (contains a corrected proof of convergence of the proposed iterative algorithm)
Additional file 1 of Use of PROMIS® to screen for depression in children with arthritis
Creators: name: Yufan Yan
name: Rychlik, Karen L.
name: Rosenman, Marc B.
name: Miller, Michael L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1 Appendix A. PROMIS Pediatric Profile 25 Survey OMR version.
Additional file 2 of Reporting and utilization of Patient-Reported Outcomes Measurement Information System® (PROMIS®) measures in orthopedic research and practice: a systematic review
Creators: name: Horn, Maggie E.
name: Reinke, Emily K.
name: Couce, Logan J.
name: Reeve, Bryce B.
name: Ledbetter, Leila
name: George, Steven Z.
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Quality Assessment.
Das Ding aus zwei Artefakten oder: Handschriften und ihre Fragmente
Creators: name: Philipowski, Katharina
Publisher: name: Edition Topoi
Year: 2018

description: Unter den Fragmenten gibt es eine Gruppe, deren Bestimmung und Handhabung spezifische Proble­me aufgibt, weil sich in ihrem Fall zwei Artefakte überlagern: Texte und Überlieferungsträger. Dabei bringt die handschriftliche Überlieferung einige Besonderheiten mit sich: Während der Druck einen Text in zahl losen identischen Exemplaren instanziieren [vervielfältigen]kann, ist in Handschriftenkul­turen Textidentität zwischen verschiedenen materiellen Realisierungen von Text – also von verschie­denen Handschriften – eine nur theoretische Möglichkeit, insofern schon allein durch Abschreibe­fehler vollständige Textidentität kaum je erreicht wird. Text und Material werden bei der Herstellung einer Handschrift für jedes Exemplar immer neu zusammengefügt. Dadurch werden mehr verschie­dene Entstehungsszenarien von Fragmentarität möglich als im Falle von serieller und maschineller Produktion.
Spelling convention sensitivity in neural language models
Creators: name: Nielsen, Elizabeth
name: Kirov, Christo
name: Roark, Brian
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: We examine whether large neural language models, trained on very large collections of varied English text, learn the potentially long-distance dependency of British versus American spelling conventions, i.e., whether spelling is consistently one or the other within model-generated strings. In contrast to long-distance dependencies in non-surface underlying structure (e.g., syntax), spelling consistency is easier to measure both in LMs and the text corpora used to train them, which can provide additional insight into certain observed model behaviors. Using a set of probe words unique to either British or American English, we first establish that training corpora exhibit substantial (though not total) consistency. A large T5 language model does appear to internalize this consistency, though only with respect to observed lexical items (not nonce words with British/American spelling patterns). We further experiment with correcting for biases in the training data by fine-tuning T5 on synthetic data that has been debiased, and find that finetuned T5 remains only somewhat sensitive to spelling consistency. Further experiments show GPT2 to be similarly limited.
Additional file 1 of Reporting and utilization of Patient-Reported Outcomes Measurement Information System® (PROMIS®) measures in orthopedic research and practice: a systematic review
Creators: name: Horn, Maggie E.
name: Reinke, Emily K.
name: Couce, Logan J.
name: Reeve, Bryce B.
name: Ledbetter, Leila
name: George, Steven Z.
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Search Strategies.
title: Impact of medical and neurological ICU complications on moderate-severe traumatic brain injury (TBI)
Creators: name: Muehlschlegel, Susanne
name: Carandang, Raphael A.
name: Ouillette, Cynthia
name: Hall, Wiley R.
name: Anderson Jr., Frederick A.
name: Goldberg, Robert J.
Publisher: name: eScholarship@UMMS
Year: 2012

description: Certain admission characteristics are known predictors of adverse outcomes in patients with moderate-severe TBI, but explain only 1/3 of outcome variability. Intensive care unit (ICU) complications occur frequently in this population, but their impact on patient outcomes remains poorly defined. In a prospective observational cohort study of 170 consecutive moderate-severe TBI patients admitted to Level I trauma center (UMASS) over the period 11/2009–2/2012, we examined the association of ICU complications and 3-month outcome (Glasgow Outcome Scale [GOS]). The mean age was 51 years, 72% were men, and the median GCS and injury severity scores were 4 and 29, respectively. Using multiple logistic regression analysis, hypotension requiring vasopressors (HRV) was the strongest predictor of poor outcome (GOS 1-3 [OR 2.8; 95% CI 1-7.5]) among medical complications. After combining medical with neurological ICU complications, brain herniation (OR 5.8; 95% CI 1.1-30.2) and intracranial rebleeding (OR 2.9; 95% CI 1-8.4) were the strongest predictors of poor outcome, while HRV approached significance (OR 2.4; 95% CI 0.9-6.4). We identified important potentially modifiable predictors of adverse outcomes after moderate-severe TBI. Confirmation of our findings in a larger cohort is warranted.
Additional file 1 of Rhamnolipids and surfactin inhibit the growth or formation of oral bacterial biofilm
Creators: name: Yamasaki, Ryota
name: Kawano, Aki
name: Yoshioka, Yoshie
name: Ariyoshi, Wataru
Publisher: name: figshare
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Additional file 1: Supplemental Fig. 1. Representative images of A. actinomycetemcomitans Y4 (A, D, G), S. mutans UA159 (B, E, H), and S. sanguinis ATCC10556 (C, F, I) biofilms as visualized by confocal microscopy. Non-treatment (0 w/v%) images (A-C), rhamnolipids treatment (0.65 w/v%) images (D-F), and surfactin treated (1.04 w/v%) images (G-H) are shown. These bacterial samples were stained by Syto9. Scale bars indicates 10 μm. Supplemental Fig. 2. Biofilm formation of (A) S. mutans UA159 and (B) S. sanguinis ATCC10556 with sucrose concentrations (0, 0.01, 0.1, and 1 w/v%). Error bars indicate standard deviations of at least three experiments.
Quantum control landscape for generation of $H$ and $T$ gates in an open qubit with both coherent and environmental drive
Creators: name: Petruhanov, Vadim
name: Pechen, Alexander
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: 81Q93

description: An important problem in quantum computation is generation of single-qubit quantum gates such as Hadamard ($H$) and $π/8$ ($T$) gates which are components of a universal set of gates. Qubits in experimental realizations of quantum computing devices are interacting with their environment. While the environment is often considered as an obstacle leading to decrease of the gate fidelity, in some cases it can be used as a resource. Here we consider the problem of optimal generation of $H$ and $T$ gates using coherent control and the environment as a resource acting on the qubit via incoherent control. For this problem, we study quantum control landscape which represents the behaviour of the infidelity as a functional of the controls. We consider three landscapes, with infidelities defined by steering between two, three (via Goerz-Reich-Koch approach), and four matrices in the qubit Hilbert space. We observe that for the $H$ gate, which is Clifford gate, for all three infidelities the distributions of minimal values obtained with gradient search have a simple form with just one peak. However, for $T$ gate which is a non-Clifford gate, the situation is surprisingly different - this distribution for the infidelity defined by two matrices also has one peak, whereas distributions for the infidelities defined by three and four matrices have two peaks, that might indicate possible existence of two isolated minima in the control landscape. Important is that among these three infidelities only those defined with three and four matrices guarantee closeness of generated gate to a target and can be used as a good measure of closeness. We study sets of optimized solutions for this most general and not treated before case of coherent and incoherent controls acting together, and discover that they form submanifolds in the control space, and unexpected, in some cases two isolated submanifolds.
description: Final published version
The face-on disk of MAXI J1836-194
Creators: name: Russell, T. D.
name: Soria, R.
name: Motch, C.
name: Pakull, M. W.
name: Torres, M. A. P.
name: Curran, P. A.
name: Jonker, P. G.
name: Miller-Jones, J. C. A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present Very Large Telescope optical spectra of the black hole candidate X-ray binary MAXI J1836-194 at the onset of its 2011 outburst. Although the spectrum was taken at the beginning of the outburst and contains a significant contribution from the optically-thin synchrotron emission that originates in the radio jet, we find that the accretion disk was already large and bright. Single-peaked, narrow H$α$ and He II $λ$4686 lines imply the most face-on accretion disk observed in a black hole low-mass X-ray binary to date, with an inclination angle between 4$^{\circ}$ and 15$^{\circ}$, assuming a black hole mass of between 5 M$_\odot$ and 12 M$_\odot$, for distances of between 4 and 10 kpc. We use New Technology Telescope observations of the system in quiescence to place strong upper limits on the mass and radius of the donor star and the orbital period. The donor is a main sequence star with a mass < 0.65 M$_{\odot}$ and a radius < 0.59 R$_{\odot}$ with an orbital period of < 4.9 hours. From those values and Roche lobe geometry constraints we find that the compact object must be >1.9 M$_{\odot}$ if the system is located 4 kpc away and >7.0 M$_{\odot}$ at 10 kpc.
description: 10 pages, accepted for publication in MNRAS
title: A Mixed-Methods Study To Characterize Pharmaceutical Marketing in the Nursing Home Setting: Off-Label Use of Atypical Antipsychotics
Creators: name: Benedicto, Camilla
name: Donovan, Jennifer L.
name: Field, Terry S.
name: Gurwitz, Jerry H.
name: Foy, Sarah
name: Harrold, Leslie R.
name: Kanaan, Abir O.
name: Lemay, Celeste A.
name: Mazor, Kathleen M.
name: Tjia, Jennifer
name: Valluri, Sruthi
name: Briesacher, Becky A.
Publisher: name: eScholarship@UMMS
Year: 2012

description: Background: Despite FDA warnings that atypical antipsychotic medications are associated with an increased risk of death when used to treat behavioral disorders in older adults with dementia, they are prescribed to nearly one-third of older U.S. nursing home (NH) residents. Reasons for their high use in NHs are poorly understood, but may include pharmaceutical marketing efforts in the NH setting.

Methods: This study is nested within an ongoing cluster randomized trial to improve the use of atypical antipsychotics in NHs. We analyzed semistructured interviews (n = 36) and surveys (n = 139) of administrators, directors of nursing and medical directors from 62 NHs in Connecticut. Using prescription drug claims from a national long-term care pharmacy, we arrayed study NHs into lowest to highest tertile of atypical antipsychotic use. We tested for differences in the receipt of information or clinical tools from pharmaceutical company representatives (PCRs) to manage dementia-related behaviors by medication use tertiles, adjusting for NH profit status, size, quality (overall, health inspections, staffing) and staffing measures (daily nurse hours per resident).

Results: Average baseline use of atypical antipsychotics ranged from 6.6 to 44.3 percent of all residents in the facility. Approximately one-quarter of NH leaders presently receive information on dementia-related behavioral management strategies from PCRs through detailing, in-service training, written or Web-based material or sponsorship as speakers. However, we did not detect statistically significant differences in the receipt of information by level of atypical antipsychotic use, NH characteristics, quality and staffing measures.

Conclusions: This first attempt to characterize pharmaceutical marketing within the NH setting did not find differences among reports of marketing efforts with respect to medication use and facility-level characteristics. However, studies across a wider geographic area should continue investigating the possible role of marketing efforts on overall use and choice of atypical antipsychotics in the NH setting.
Der Karneval des Properz
Creators: name: Schwindt, Jürgen Paul
Publisher: name: Edition Topoi
Year: 2018

description: Die objektepistemologische Untersuchung erweist sich im Umgang mit Texten der augusteischen Literatur als produktive Methode, unser Wissen über die (Selbst)Organisation komplexer Dichtungen zu erweitern. Sie ist geeignet, die traditionelle Sprach- und Stilbeobachtung in den größeren Horizont einer Theorie der Gegenständlichkeit zu rücken. Das erlaubt präzisere Aussagen zur Bestimmung des ‘Themas‘ wie des ‘Weltbezuges‘ der Dichtung. In zahlreichen Texten der Übergangszeit zwischen der römischen Republik und dem augusteischen Prinzipat sind es die Dinge, die die Erschütterung konventioneller Wahrnehmungs- und Urteilsweisen am zuverlässigsten bezeugen. So kann das erotisch-melancholische Kammerspiel des Properz zum Indikator eines epochalen Wandels werden.
title: Racial and Socioeconomic Disparities in Biological and Perceived Chronic Stress: Does Group Identification Matter?
Creators: name: O'Brien, Kymberlee M.
name: Tronick, Ed
name: Moore, Celia L.
Publisher: name: eScholarship@UMMS
Year: 2012

description: Objective: Hair cortisol has been recently identified as a biological index of stress via long-term alterations in HPA activity, although population norms and relationships to perceived stress measures have not yet been established.

In the present study, 135 adults (ages 18-66; M = 30.26, SD = 12.80; 87 females) from the diverse UMass Boston campus participated in a study assessing chronic stress (via hair cortisol), perceived stress (via self-reported indices), and health indictors (WHR and blood pressure). Since hair grows on average 1cm per month, we captured approximately 3 months of retrospective cortisol levels.

Results: Hair cortisol was uncorrelated with subjective stress indices, unless collapsed into a composite across several domains. Differences in objective and subjective stress measures were found for sociodemographic factors including racial/ethnic identity, sex, and SES. Specifically, highest hair cortisol levels were found by gender (males were higher) and race (minorities were higher), whereas subjective stress was positively associated with race (minorities were higher), and negatively associated with SES and age. Subjective stress was not significantly different by gender.

Examining interactions of predictors, results obtain that Race by SES predicted hair cortisol, perceived stress, well-being, and health indicators but in unexpected directions. Minorities in high SES had the greatest hair cortisol, subjective stress, systolic blood pressure, waist cm, and lower reported well-being, compared to the non-minority high SES group

The unexpected findings of deleterious outcomes for high SES minorities suggest the necessity of further studies examining social identity, the prevalence of discrimination in high SES, and potential protective factors.

Moreover, these findings give evidence that hair cortisol, as a biomarker of long-term HPA activity, may not always be correlated with perceptions of stress across specific domains, but rather may provide a broad non-specific assessment of chronic stress, where objective and subjective indices may be uncoupled.
title: Healthy Food Accessibility in Grocery Stores in Central Massachusetts
Creators: name: Olendzki, Barbara C.
name: Patil, Viji
name: Chen, Lili
name: Procter-Gray, Elizabeth
name: Li, Wenjun
Publisher: name: eScholarship@UMMS
Year: 2012

description: BACKGROUND. Accessibility to healthy food is one of the most influential community-level factors affecting obesity and chronic disease. The Community Nutrition Environment Evaluation Data System (C-NEEDS) is a set of instruments for objectively assessing availability and quality of 61 major healthy and unhealthy food items in foods stores in the Northeast region.

METHODS. The C-NEEDS was developed considering seasonal variations, cultural relevance and utility to cardiovascular health research. Both inter- and intra-rater reliability tests showed a high degree of agreement. Using the instruments, we conducted four rounds of longitudinal surveys of 107 grocery stores in Worcester County, Massachusetts between 2007 and 2010. A healthy food availability index (HFAI, 0-37 points) was calculated for each store, a higher score indicating a greater availability and better quality of healthy foods. Using linear regression models, we examined variations in HFAI in relation to community household income and housing density.

RESULTS. Store-level HFAI did not vary significantly by tertile of community median income, but did vary by housing density. High-density communities (upper tertile) had the greatest percentage of stores in the top HFAI tertile (34-37 points). Middle-density communities had the greatest percentage of stores in the low HFAI tertile (0-17 points). A majority of the stores located in low-density communities had middle range of HFAI (18-33 points). The mean HFAI increased with each successive round of grocery store surveys (β=2.02/round [95% confidence interval 0.74-3.31]).

CONCLUSION. Access to healthy foods improved slightly over time, however, notable disparities still existed in Central Massachusetts during the study period. Better access was associated with community housing density but not median household income. Further studies on the causes of the disparities may inform public health organizations about necessary community actions to reduce these disparities.
Dinge und Wissen
Creators: name: Selz, Gebhard J.
Publisher: name: Edition Topoi
Year: 2018

description: Grundlegend für eine altorientalistische Perspektive auf “epistemische Praktiken an, mit und infolge von Dingen“ ist, dass dem ontologischen Status von ‘Objekten’ im Alten Orient kein besonderes Gewicht beigemessen wurde. Physische Objekte und abgeleitete, auch mentale Objekte, erschienen analog konzipiert; die mit solchen Objekten durchgeführten Manipulationen sind strukturell ähnlich, die Grenzen sind fließend. In ihren intentionalen und funktionalen Aspekten erweisen sich Objekte als Teil eines (semantischen) Netzwerkes, offen für kollektive und individuelle Selektionsmecha­nismen. Die Doppelung dieser Prozesse bei der Beschreibung der Welt der Objekte verweist auf die Grenzen altertumswissenschaftlicher ‘Narrative’, ihre unabweisbare Vorläufigkeit bzw. ihr Modell­charakter.