cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A pathogenic role of plasmacytoid dendritic cells in autoimmunity and chronic viral infection
Creators: name: Su, Lishan
name: Barrat, Frank J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Following the discovery of plasmacytoid dendritic cells (pDCs) and of their extraordinary ability to produce type I IFNs (IFN-I)
in response to TLR7 and TLR9 stimulation, it is assumed that their main function is to participate in the antiviral response. There
is increasing evidence suggesting that pDCs and/or IFN-I can also have a detrimental role in a number of inflammatory and
autoimmune diseases, in the context of chronic viral infections and in cancers. Whether these cells should be targeted in
patients and how much of their biology is connected to IFN-I production remains unclear and is discussed here.
The Development Model of Participation in Academic Administration by Using Team Coaching Process to Improving the Quality for Students of Nonsa Ardradamnuay School under the Kalasin Primary Educational Area Office 2
Creators: name: Prasupsuk Srihongthong
Publisher: name: DR.KEN Institute of Academic Development and Promotion.
Year: 2022
Subjects: Model Development
Academic Administration
Participatory Management
Team Coaching Process

description: Interdisciplinary Academic and Research Journal, 2, 6, 35-58
การเปิดรับสื่อ การรับรู้ ความรู้ และพฤติกรรมด้านการป้องกันในสถานการณ์การระบาดใหญ่ทั่วโลกของนักเรียนมัธยมศึกษาตอนต้น: กรณีโควิด 19
Creators: name: กัลยภัฏร์ ศรีไพโรจน์
Publisher: name: Thailand National Sports University
Year: 2022
Subjects: การเปิดรับสื่อ
การรับรู้
ความรู้
พฤติกรรมด้านการป้องกันโควิด-19

description: Academic Journal of Thailand National Sports University, 14, 3, 131 - 142
Hepatitis B virus–induced imbalance of inflammatory and antiviral signaling by differential phosphorylation of STAT1 in human monocytes
Creators: name: Yang, Miaomiao
name: Tu, Zhengkun
name: Cui, An
name: Lv, Guoyue
name: Wu, Zhihui
name: Song, Hongxiao
name: Niu, Junqi
name: Crispe, Ian Nicholas
name: Zhu, Kangshun
name: Chi, Xiumei
name: Li, Tianyang
name: Tan, Guangyun
name: Yang, Yang
name: Su, Lishan
name: Li, Haijun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: It is not clear how hepatitis B virus (HBV) modulates host immunity during chronic infection. In addition to the key mediators of
inflammatory response in viral infection, monocytes also express a high-level IFN-stimulated gene, CH25H, upon response to IFN-a
exerting an antiviral effect. In this study, the mechanism by which HBV manipulates IFN signaling in human monocytes was
investigated. We observed that monocytes from chronic hepatitis B patients express lower levels of IFN signaling/stimulated genes
and higher levels of inflammatory cytokines compared with healthy donors. HBV induces monocyte production of inflammatory
cytokines via TLR2/MyD88/NF-kB signaling and STAT1-Ser727 phosphorylation and inhibits IFN-a–induced stat1, stat2, and
ch25h expression through the inhibition of STAT1-Tyr701 phosphorylation and in an IL-10–dependent, partially autocrine
manner. Further, we found that enhancement of STAT1 activity with a small molecule (2-NP) rescued HBV-mediated inhibition
of IFN signaling and counteracted the induction of inflammatory cytokines. In conclusion, HBV contributes to the monocyte
inflammatory response but inhibits their IFN-a/b responsiveness to impair antiviral innate immunity. These effects are mediated
via differential phosphorylation of Tyr701 and Ser727 of STAT1.
Chimera states in bursting neurons
Creators: name: Bera, Bidesh K.
name: Ghosh, Dibakar
name: Lakshmanan, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We study the existence of chimera states in pulse-coupled networks of bursting Hindmarsh-Rose neurons with nonlocal, global and local (nearest neighbor) couplings. Through a linear stability analysis, we discuss the behavior of stability function in the incoherent (i.e. disorder), coherent, chimera and multi-chimera states. Surprisingly, we find that chimera and multi-chimera states occur even using local nearest neighbor interaction in a network of identical bursting neurons alone. This is in contrast with the existence of chimera states in populations of nonlocally or globally coupled oscillators. A chemical synaptic coupling function is used which plays a key role in the emergence of chimera states in bursting neurons. Existence of chimera, multi-chimera, coherent and disordered states are confirmed by means of the recently introduced statistical measures and mean phase velocity.
description: 10 pages, 11 figures; Accepted for publication in PRE
Contact interaction in an unitary ultracold Fermi gas
Creators: name: Pessoa, Renato
name: Gandolfi, S.
name: Vitiello, S. A.
name: Schmidt, K. E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: An ultracold Fermi atomic gas at unitarity presents universal properties that in the diluted limit can be well described by a contact interaction. By employing a guide function with correct boundary conditions and making simple modifications to the sampling procedure we are able to handle for the first time a true contact interaction in a quantum Monte Carlo calculation. The results are obtained with small variances. Our calculations for the Bertsch and contact parameters are in excellent agreement with published experiments. The possibility of using a more faithfully description of ultracold atomic gases can help uncover features yet unknown of the ultracold atomic gases. In addition, this work paves the way to perform quantum Monte Carlo calculations for systems interacting with contact interactions, where in many cases the description using potentials with finite effective range might not be accurate.
Activated NK cells kill hepatic stellate cells via p38/PI3K signaling in a TRAIL-involved degranulation manner
Creators: name: Crispe, Ian Nicholas
name: Yang, Yang
name: Cui, An
name: Li, Tianyang
name: Song, Hongxiao
name: Li, Haijun
name: Liu, Yanhou
name: Su, Lishan
name: Tu, Zhengkun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: NK cells are important in regulating hepatic fibrosis via their cytotoxic killing of hepatic stellate
cells (HSCs). NK cells are activated by both cytokines such as IL-12 and IL-18, and innate immune
stimuli such as ligation of TLRs. The secretion of IL-18 depends upon activation of the inflammasome,
whereas TLRs are stimulated by microbial products. In the case of NK cells, IL-18 acts synergistically
with stimulation of TLR3 to cause cell activation and cytotoxic function. In the present
study, we activated NK cells to kill HSCs via IL-18 and TLR3 ligand stimulation, and dissected the
signaling pathways or molecules critical for such activation or killing. We find that such activation
depends on signaling via the p38/PI3K/AKT pathway, and that the activatedNK cells mediate
HSC death in a TRAIL-involved mechanism. As liver fibrosis is a major global health problem with
no good solution, these results emphasize that the p38/PI3K/AKT pathway in NK cells may be a
novel drug target to promote fibrosis regression.
หลักสูตรรายวิชาเพิ่มเติมพลศึกษาโดยใช้ทฤษฎีการตั้งเป้าหมายเพื่อเสริมสร้างสมาธิของนักเรียนประถมศึกษา
Creators: name: กาญจนา เรืองอำพันธุ์
Publisher: name: Thailand National Sports University
Year: 2022
Subjects: หลักสูตรรายวิชาเพิ่มเติมพลศึกษา
ทฤษฎีการตั้งเป้าหมาย
นักเรียนประถมศึกษา
การเสริมสร้างสมาธิ

description: Academic Journal of Thailand National Sports University, 14, 3, 143 - 154
ผลการจัดการเรียนรู้สุขศึกษาโดยใช้กระบวนการชี้แนะที่มีต่อผลสัมฤทธิ์ทางการเรียนและทักษะด้านสารสนเทศ สื่อ และเทคโนโลยีของนักเรียนมัธยมศึกษา
Creators: name: กิตติภพ กุลฐิติโชติ
Publisher: name: Thailand National Sports University
Year: 2022
Subjects: การจัดการเรียนรู้สุขศึกษา
การสอนแบบชี้แนะ
ทักษะด้านสารสนเทศ สื่อ และเทคโนโลยี

description: Academic Journal of Thailand National Sports University, 14, 3, 155 - 166
Humanized immune system mouse models: progress, challenges and opportunities
Creators: name: Kumar, Priti
name: PrabhuDas, Mercy
name: Sanders-Beer, Brigitte
name: Shultz, Leonard D.
name: Bridges, Sandra
name: Ferguson, Stacy
name: Pelanda, Roberta
name: Brehm, Michael A.
name: Palucka, Karolina
name: Allen, Todd M.
name: Su, Lishan
name: Mirochnitchenko, Oleg
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Over 30 key leaders in the field
participated in a 1-day workshop
entitled ‘Recent Advances and
Opportunities in the Development and
Use of Humanized Immune System
Mouse Models’ to discuss the benefits
and limitations of using human fetal
tissue versus non-fetal tissue sources to
generate mice with a humanized immune
system. This Comment summarizes
the workshop discussions, including
highlights of some of the key advances
made through the use of humanized mice
in improving the understanding of immune
system function and developing novel
therapeutics for the treatment of infectious,
immunological and allergic diseases, as well
as current challenges in the production,
characterization and utilization of these
animal models.
ผลของโปรแกรมการออกกำลังกายโดยใช้น้ำหนักตัวเป็นแรงต้านร่วมกับฟิตเนสบอร์ดเกมที่มีต่อสมรรถภาพทางกายของนักเรียนชั้นประถมศึกษาตอนปลาย
Creators: name: เจตนิพัทธ์ ปิ่นแก้ว
Publisher: name: Thailand National Sports University
Year: 2022
Subjects: โปรแกรมการออกกำลังกาย
การออกกำลังกายโดยใช้น้ำหนักตัวเป็นแรงต้าน
ฟิตเนสบอร์ดเกม
สมรรถภาพทางกาย

description: Academic Journal of Thailand National Sports University, 14, 3, 167 - 178
Pathogenic Role of Type I Interferons in HIV-Induced Immune Impairments in Humanized Mice
Creators: name: Su, Lishan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Purpose of Review: Recent findings on the critical pathogenic role of type 1 interferons (IFN-I) in HIV-1 persistence in humanized mice suggest that inhibiting IFN-I signaling transiently will reverse HIV-induced inflammatory diseases and rescue anti-HIV immunity to control HIV-1 reservoirs. Recent Findings: In both humanized mice and in monkeys, IFN-I signaling is functionally defined to play an important role in suppressing early HIV-1 and SIV infection. During persistent infection in humanized mice, however, IFN-I signaling is revealed to induce T cell depletion and impairment. Interestingly, in HIV-infected mice with effective combination antiretroviral therapy (cART), blocking IFN-I signaling reverses HIV-induced inflammation, rescues anti-HIV T cells, and reduces HIV-1 reservoirs. Summary: These findings functionally define the role of IFN-I in HIV-1 reservoir persistence and suggest that blocking IFN-I signaling will provide a novel therapeutic strategy to (i) reverse inflammation-associated diseases in HIV patients under cART, (ii) rescue host anti-HIV immunity, and (iii) reduce or control HIV-1 reservoirs.
แนวทางการจัดการโรงเรียนสอนกีฬาเทควันโดในประเทศไทย
Creators: name: ณัชชารีย์ วิทยประพัฒน์
Publisher: name: Thailand National Sports University
Year: 2022
Subjects: แนวทางการจัดการ
โรงเรียนสอนกีฬาเทควันโด

description: Academic Journal of Thailand National Sports University, 14, 3, 179 - 190
สภาพและปัญหาการจัดการเรียนรู้วิชาพลศึกษาในโรงเรียน สังกัดสำนักงานเขตพื้นที่การศึกษามัธยมศึกษาตรัง กระบี่
Creators: name: นุชรินทร์ สมศรี
Publisher: name: Thailand National Sports University
Year: 2022
Subjects: การจัดการเรียนรู้
วิชาพลศึกษา
ครูพลศึกษา

description: Academic Journal of Thailand National Sports University, 14, 3, 191 - 200
Quantum versus mean-field collapse in a many-body system
Creators: name: Astrakharchik, G. E.
name: Malomed, B. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: The recent analysis, based on the mean-field approximation (MFA), has predicted that the critical quantum collapse of the bosonic wave function, pulled to the center by the inverse-square potential in the three-dimensional space, is suppressed by the repulsive cubic nonlinearity in the bosonic gas, the collapsing ground state being replaced by a regular one. We demonstrate that a similar stabilization acts in a quantum many-body system, beyond the MFA. While the collapse remains possible, repulsive two-particle interactions give rise to a metastable gaseous state, which is separated by a potential barrier from the collapsing regime. The stability of this state improves with the increase of the number of particles. The results are produced by calculations of the variational energy, with the help of the Monte Carlo method.
description: 10 pages, 4 figures
IgG Fc-binding motif-conjugated HIV-1 fusion inhibitor exhibits improved potency and in vivo half-life: Potential application in combination with broad neutralizing antibodies
Creators: name: Qin, Chuan
name: Li, Guangming
name: Wang, Qian
name: Xu, Wei
name: Lu, Lu
name: Su, Lishan
name: Bi, Wenwen
name: Cheng, Liang
name: Jiang, Shibo
name: Wang, Qi
name: Xue, Jing
name: Xia, Shuai
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: The clinical application of conventional peptide drugs, such as the HIV-1 fusion inhibitor enfuvirtide,
is limited by their short half-life in vivo. To overcome this limitation, we developed a
new strategy to extend the in vivo half-life of a short HIV-1 fusion inhibitory peptide, CP24, by
fusing it with the human IgG Fc-binding peptide (IBP). The newly engineered peptide IBPCP24
exhibited potent and broad anti-HIV-1 activity with IC50 values ranging from 0.2 to
173.7 nM for inhibiting a broad spectrum of HIV-1 strains with different subtypes and tropisms,
including those resistant to enfuvirtide. Most importantly, its half-life in the plasma of
rhesus monkeys was 46.1 h, about 26- and 14-fold longer than that of CP24 (t1/2 = 1.7 h) and
enfuvirtide (t1/2 = 3 h), respectively. IBP-CP24 intravenously administered in rhesus monkeys
could not induce significant IBP-CP24-specific antibody response and it showed no obvious
in vitro or in vivo toxicity. In the prophylactic study, humanized mice pretreated with IBPCP24
were protected from HIV-1 infection. As a therapeutic treatment, coadministration of
IBP-CP24 and normal human IgG to humanized mice with chronic HIV-1 infection resulted in
a significant decrease of plasma viremia. Combining IBP-CP24 with a broad neutralizing antibody
(bNAb) targeting CD4-binding site (CD4bs) in gp120 or a membrane proximal external
region (MPER) in gp41 exhibited synergistic effect, resulting in significant dose-reduction of
the bNAb and IBP-CP24. These results suggest that IBP-CP24 has the potential to be further
developed as a new HIV-1 fusion inhibitor-based, long-acting anti-HIV drug that can be used
alone or in combination with a bNAb for treatment and prevention of HIV-1 infection.
Dynamic Spectrum Sensing Through Accelerated Particle Swarm Optimization
Creators: name: Paschos, Alexandros E.
name: Kapinas, Vasileios M.
name: Ntouni, Georgia D.
name: Hadjileontiadis, Leontios J.
name: Karagiannidis, George K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optimization and Control (math.OC)
subject: Information Theory (cs.IT)
subject: Applications (stat.AP)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: In this paper, a novel optimization algorithm, called the acceleration-aided particle swarm optimization (AAPSO), is proposed for reliable dynamic spectrum sensing in cognitive radio networks. In A-APSO, the acceleration variable of the particles in the swarm is also considered in the search space of the optimization problem. We show that the proposed A-APSO based spectrum sensing technique is more efficient in terms of performance than the corresponding one based on the standard particle swarm optimization algorithm.
description: 4 pages, 3 figures, 2 algorithms, 1 table
SENP3-mediated host defense response contains HBV replication and restores protein synthesis
Creators: name: Han, Yan
name: Tung, Kuei-Ling
name: Wan, Ji
name: Varanko, Anastasia
name: Li, Xiaodong
name: Rakhilin, Nikolai
name: Qian, Shu-Bing
name: Xin, Yongning
name: Wang, Zhuo
name: Shen, Xiling
name: Liu, Botao
name: Murthy, Preetish Kadur Lakshminarasimha
name: Guy, Cynthia D.
name: Li, Feng
name: Su, Lishan
name: Xi, Rui
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Certain organs are capable of containing the replication of various types of viruses. In the
liver, infection of Hepatitis B virus (HBV), the etiological factor of Hepatitis B and hepatocellular
carcinoma (HCC), often remains asymptomatic and leads to a chronic carrier state. Here
we investigated how hepatocytes contain HBV replication and promote their own survival by
orchestrating a translational defense mechanism via the stress-sensitive SUMO-2/3-specific
peptidase SENP3. We found that SENP3 expression level decreased in HBV-infected hepatocytes
in various models including HepG2-NTCP cell lines and a humanized mouse model.
Downregulation of SENP3 reduced HBV replication and boosted host protein translation.
We also discovered that IQGAP2, a Ras GTPase-activating-like protein, is a key substrate
for SENP3-mediated de-SUMOylation. Downregulation of SENP3 in HBV infected cells facilitated
IQGAP2 SUMOylation and degradation, which leads to suppression of HBV gene
expression and restoration of global translation of host genes via modulation of AKT phosphorylation.
Thus, The SENP3-IQGAP2 de-SUMOylation axis is a host defense mechanism
of hepatocytes that restores host protein translation and suppresses HBV gene expression.
Two-fluid simulations of an aerated lab-scale bioreactor
Creators: name: Jamshidian, Roya
name: Scully, James
name: VAN DEN AKKER, HARRY
Publisher: name: University of Limerick
Year: 2023
Subjects: classificationCode: 40
subject: Engineering

description: We report the findings of a detailed assessment of various options for computational two-fluid RANS simulations of an aerated agitated 2-L bioreactor equipped with a single baffle and several dip tubes. The simulations were carried out by using the commercial flow solver ANSYS/Fluent. Our focus was on (1) the outlet condition at the liquid’s surface (i.e., including an air head space in the simulation yes or no); (2) the choice between the steady-state Multiple Reference Frames (MRF) approach for modelling the impeller rotation and the dynamic Sliding Mesh (SM) option; (3) the choice between two computational meshes (mosaic or polyhedral); and (4) the effect of using either the realizable k-ε model or the SST k-ω model for dealing with the turbulence in combination with different values for the fixed bubble size (either 1.8 or 2.8 mm). The final conclusion is that the SM impeller model in combination with a polyhedral computational mesh and the SST k-ω turbulence model is to be preferred. All simulations suffer from the occurrence of spurious velocities larger than the impeller tip velocity.
Implementing turbulence transport in the CRONOS framework and application to the propagation of CMEs
Creators: name: Wiengarten, Tobias
name: Fichtner, Horst
name: Kleimann, Jens
name: Kissmann, Ralf
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: We present the implementation of turbulence transport equations in addition to the Reynolds-averaged MHD equations within the Cronos framework. The model is validated by comparisons with earlier findings before it is extended to be applicable to regions in the solar wind that are not highly super-Alfvénic. We find that the respective additional terms result in absolute normalized cross-helicity to decline more slowly, while a proper implementation of the mixing terms can even lead to increased cross-helicities in the inner heliosphere. The model extension allows to place the inner boundary of the simulations closer to the Sun, where we choose its location at 0.1 AU for future application to the Wang-Sheeley-Arge model. Here, we concentrate on effects on the turbulence evolution for transient events by injecting a coronal mass ejection (CME). We find that the steep gradients and shocks associated with these structures result in enhanced turbulence levels and reduced cross-helicity. Our results can now be used straightforwardly for studying the transport of charged energetic particles, where the elements of the diffusion tensor can now benefit from the self-consistently computed solar wind turbulence. Furthermore, we find that there is no strong back-reaction of the turbulence on the large-scale flow so that CME studies concentrating on the latter need not be extended to include turbulence transport effects.
Intrinsic spin-orbit interaction in diffusive normal wire Josephson weak links: supercurrent and density of states
Creators: name: Arjoranta, Juho
name: Heikkila, Tero T.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study the effect of the intrinsic (Rashba or Dresselhaus) spin-orbit interaction in superconductor--nanowire--superconductor (SNS) weak links in the presence of a spin-splitting field that can result either from an intrinsic exchange field or the Zeeman effect of an applied field. We solve the full non-linear Usadel equations numerically and analyze the resulting supercurrent through the weak link and the behavior of the density of states in the center of the wire. We point out how the presence of the spin-orbit interaction gives rise to a long-range spin triplet supercurrent, which remains finite even in the limit of very large exchange fields. In particular, we show how rotating the field leads to a sequence of transitions between the 0 and $π$ states as a function of the angle between the exchange field and the spin-orbit field. Simultaneously, the triplet pairing leads to a zero-energy peak in the density of states. We proceed by solving the linearized Usadel equations, showing the correspondence to the solutions of the full equations and detail the emergence of the long-range supercurrent components. Our studies are relevant for on-going investigations of supercurrent in semiconductor nanowires in the limit of several channels and in the presence of disorder.
description: 11 pages, 10 figures; updated discussion of the angular dependence of the supercurrent
Enterococcus faecium LCT-EF20 Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2012
Subjects: Genome sequencing and assembly
Monoisolate

description: Enterococcus faecium is a Gram-positive, alpha hemolytic or nonhemolytic bacterium in the genus Enterococcus. It can be commensal (innocuous, coexisting organism) in the human intestine, but it may also be pathogenic, causing diseases such as neonatal meningitis. We want to find some mutations of the strain placed in the radiation environment of outer space. Culture of Enterococcus faecium CGMCC 1.2136 that spent 17 days in space aboard the Shenzhou 8 spacecraft and collected Nov-2011.
SUPPLEMENTARY INFORMATION from The origin of modern patterns of continental diversity in Mauritiinae palms: the Neotropical museum and the Afrotropical graveyard
Creators: name: Bacon, Christine D.
name: Silvestro, Daniele
name: Hoorn, Carina
name: Bogotá-Ángel, Giovanni
name: Antonelli, Alexandre
name: Chazot, Nicolas
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences
subject: 60301 Animal Systematics and Taxonomy
subject: 60310 Plant Systematics and Taxonomy

description: While the latitudinal diversity gradient has received much attention, biodiversity and species richness also vary between continents across similar latitudes. Fossil information can be leveraged to understand the evolutionary mechanisms that generated such variation between continents of similar latitudes. We integrated fossil data into a phylogenetic analysis of the Mauritiinae palms, whose extant diversity is restricted to the Neotropics, but extended across Africa and India during most of the Cenozoic. Mauritiinae diverged from its sister lineage Raphiinae ca 106 Ma. Using ancestral state estimation and a lineage through time analysis, we found that diversity arose globally during the late Cretaceous and Paleocene across South America, Africa and India. The Paleocene–Eocene transition (ca 56 Ma) marked the end of global Mauritiinae expansion, and the beginning of their decline in both Africa and India. Mauritiinae disappeared from the Indian subcontinent and Africa at the end of the Eocene and the Miocene, respectively. By contrast, Neotropical diversity steadily increased over the last 80 Ma. Taken together, our results suggest that the Neotropics functioned as a continental-scale refuge for Mauritiinae palms, where lineages survived and diversified while global climatic changes that drastically reduced rainforests led to their demise on other continents.
Enterococcus faecium LCT-EF258 Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2012
Subjects: Genome sequencing and assembly
Monoisolate

description: Enterococcus faecium is a Gram-positive, alpha hemolytic or nonhemolytic bacterium in the genus Enterococcus. It can be commensal (innocuous, coexisting organism) in the human intestine, but it may also be pathogenic, causing diseases such as neonatal meningitis. We want to find some mutations of the strain placed in the radiation environment of outer space. Culture of Enterococcus faecium CGMCC 1.2136 that spent 17 days in space aboard the Shenzhou 8 spacecraft and collected Nov-2011.
Cosmic Rays from the Knee to the Ankle
Creators: name: Haungs, Andreas
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Investigations of the energy spectrum as well as the mass composition of cosmic rays in the energy range of PeVto EeV are important for understanding both, the origin of the galactic and the extragalactic cosmic rays. Recently, three modern experimental installations (KASCADE-Grande, IceTop, Tunka-133), dedicated to investigate this primary energy range, have published new results on the all-particle energy spectrum. In this short review these results are presented and the similarities and differences discussed. In addition, the effects of using different hadronic interaction models for interpreting the measured air-shower data will be examined. Finally, a brief discussion on the question if the present results are in agreement or in contradiction with astrophysical models for the transition from galactic to 10 pagesextragalactic origin of cosmic rays completes this paper.
description: 10 pages, proceedings of TAUP 2013 conference
Data from: Factors affecting the nesting success of Swainson's thrush (Catharus ustulatus) along an elevational gradient
Creators: name: Deckel, Sarah
Publisher: name: Zenodo
Year: 2023
Subjects: RMark
nest survival
daily survival rates
montane
breeding birds

description: Montane birds face several ecological challenges during the breeding season, including nest predators, competition for territory, and food availability. The continuing effects of climate change are causing shifts in these plant and animal communities, as well as changes in abiotic factors such as increased temperature and precipitation effects, adding additional stressors that could affect nest survival, putting their populations at risk. The Swainson's thrush (Catharus ustulatus) is migratory songbird which is moderately common and breeds along a wide elevation gradient within this system (200-1,250m). Populations of Swainson's thrush were once declining, though recent research shows their ranges to be shifting downwards, potentially as the result of increased precipitation and temperature at higher elevations. Although lower elevations might be more favorable in terms of climactic conditions, nest predation is higher at lower elevations in other systems. Thus, this species might be faced with the opposing pressures of adverse climactic conditions at higher elevations and increased predation at lower elevations. Nest survival is a fundamental process to population size, and therefore, is important in evaluating how montane breeding birds are adjusting to the changing climate. We monitored nests of Swainson's thrush along an elevation gradient in the White Mountain National Forest in New Hampshire in 2016, 2018, 2019 and 2021 at two sites: Mt. Jefferson (500-1,250m) and Bartlett Experimental Forest (200-300m). We found a significant negative effect of rain intensity (millimeters per hour per day) as well as a negative interaction effect of elevation with minimum daily temperature and average daily temperature, on the daily survival rate of Swainson's thrush. Our results provide evidence that nesting survival of montane breeding birds could be at risk as heavier precipitation events become more frequent and intense, a likely outcome due to the changing climate within the White Mountains and other montane ecosystems, putting other passerine species at risk in this system.
description: R studio is needed to open the file(s), but RMark is needed to run the code.Funding provided by: U.S. Forest Service
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100006959
Award Number: Funding provided by: National Science Foundation
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000001
Award Number:
Mycobacteroides abscessus 9808 Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2013
Subjects: Genome sequencing and assembly
Monoisolate

description: This M. abscessus strain was isolated from the wound exudate of patients in the postoperative infection outbreak happened in a hospital in 1998, in Shenzhen, Guangdong, China.
A simple formula for a planet's mean annual insolation by latitude
Creators: name: Nadeau, Alice
name: McGehee, Richard
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: FOS: Physical sciences

description: In this paper, we use a sixth order Legendre series expansion to approximate the mean annual insolation by latitude of a planet with obliquity angle $β$, leading to faster computations with little loss in the accuracy of results. We discuss differences between our method and selected computational results for insolation found in the literature.
description: 5 pages, 2 figures
The peculiar distribution of CH3CN in IRC+10216 seen by ALMA
Creators: name: Agundez, M.
name: Cernicharo, J.
name: Quintana-Lacaci, G.
name: Prieto, L. Velilla
name: Castro-Carrizo, A.
name: Marcelino, N.
name: Guelin, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: IRC+10216 is a circumstellar envelope around a carbon-rich evolved star which contains a large variety of molecules. According to interferometric observations, molecules are distributed either concentrated around the central star or as a hollow shell with a radius of 15". We present ALMA Cycle 0 band 6 observations of the J=14-13 rotational transition of CH3CN in IRC+10216, obtained with an angular resolution of 0.76x0.61". The bulk of the emission is distributed as a hollow shell located at just 2" from the star, with a void of emission in the central region up to a radius of 1". This spatial distribution is markedly different from those found to date in this source for other molecules. Our analysis indicate that methyl cyanide is not formed neither in the stellar photosphere nor far in the outer envelope, but at radial distances as short as 1-2", reaching a maximum abundance of 0.02 molecules cm-3 at 2" from the star. Standard chemical models of IRC+10216 predict that the bulk of CH3CN molecules should be present at a radius of 15", where other species such as polyyne radicals and cyanopolyynes are observed, with an additional inner component within 1" from the star. The non-uniform structure of the circumstellar envelope and grain surface processes are discussed as possible causes of the peculiar distribution of methyl cyanide in IRC+10216.
description: Accepted for publication in ApJ. Revised version includes updates following the recommendations of our referee
Vpr enhances HIV-1 Env processing and virion infectivity in macrophages by modulating TET2-dependent IFITM3 expression
Creators: name: Wang, Qi
name: Su, Lishan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: HIV-1 Vpr enhances viral replication in human macrophages via multiple mechanisms that are not clearly defined. It does not affect HIV-1 virion production during the first round of infection. We have recently discovered that Vpr targets the DNA demethylase TET2 for degradation, which leads to sustained interleukin-6 (IL-6) expression and elevated HIV-1 replication. We report here that Vpr enhanced Env processing in infected macrophages, associated with increased Env incorporation into virions with higher infectivity. Interestingly, IFITM3 was constitutively expressed in macrophages in a TET2-dependent fashion. We showed that Vprenhanced Env processing depended genetically on TET2 and IFITM3. We further showed that Vpr reduced IFITM3 expression by reducing demethylation of the IFITM3 promoter in macrophages, associated with degradation of TET2 and reduced TET2 binding to the IFITIM3 promoter. Our findings indicate that the Vpr-TET2 axis enhances HIV-1 replication in macrophages via two independent mechanisms: Reduced IFTIM3 expression to enhance Env processing and virion infectivity and sustained IL-6 expression to increase HIV-1 replication. The Vpr-TET2 axis may provide a novel target to develop therapeutics to inhibit HIV-1 infection and pathogenesis.
Streptomyces sp. GXT6 Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2013
Subjects: Genome sequencing and assembly
Monoisolate

description: Streptomyces sp. GXT6 was isolated from a planting cassava soil and identified by State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi University,Nanning, Guangxi, China.
title: Τα spolia στην μοντέρνα αρχιτεκτονική ως μέσο για την αναζήτηση της τοπικότητας στον ελλαδικό χώρο
title: Spolia in modern architecture as a medium on the search for locality in Greece
Creators: name: Τεζαρης Εμμανουηλ
Publisher: name: Technical University of Crete
Year: 2023

description: Σκοπός της ερευνητικής εργασίας είναι η διερεύνηση των spolia, των επαναχρησιμοποιημένων οικοδομικών υλικών από κτίσματα που έχουν κατεδαφιστεί, ως ένα από τα μέσα αναζήτησης της τοπικότητας σε κατοικίες του Ελληνικού Μεταπολεμικού Μοντερνισμού. Η χρήση των spolia στην Μεταπολεμική Ελλάδα είναι ευρεία λόγω της πληθώρας των οικοδομικών αποβλήτων και αποτέλεσμα της έντονης ανοικοδόμησης και παράλληλα κατεδάφισης των κτισμάτων του 19ου αι. και των αρχών του 20ου. Η έννοια του θραύσματος αναλύεται σε αυτή την περίπτωση, υπό την μορφή των spolia, ως ένα δοχείο συλλογικής μνήμης με αναγωγές στο παρελθόν και την ιστορία, πράγμα το οποίο δημιουργεί αντίθεση με τα προτάγματα του μοντέρνου κινήματος. Η εργασία πραγματεύεται μοντέρνες κατοικίες μεταπολεμικές, όπου εντοπίζεται ενδιαφέρουσα χρήση  των spolia χωρίς να απομακρύνονται από το πνεύμα του Μοντερνισμού. Ανάμεσα σε άλλα επιχειρεί να απαντήσει ερωτήματα:
•	Ποιοι οι συνθετικοί χειρισμοί στη χρήση των spolia στις κατοικίες του Ελληνικού Μεταπολεμικού Μοντερνισμού και πως συνδιαλέγεται με τις κανονιστικές αρχές του ;
•	Εμφανίζεται σχέση ανάμεσα στην επιλογή των spolia και τον τόπο καταγωγής των ιδιοκτητών ; Αν ναι, πώς ερμηνεύεται;

description: The aim of this research project is to investigate spolia, reused building materials from demolished buildings, as one of the means of searching for locality in Greek Postwar Modernist residences. The use of spolia in post-war Greece is widespread due to the abundance of construction waste and the result of the intensive reconstruction and demolition of 19th century buildings and early 20th century. The concept of the fragment is analysed in this case, in the form of spolia, as a container of collective memory with references to the past and history, which creates a contradiction with the precepts of the modern movement. The paper deals with post-war modern houses, where an interesting use of spolia is found without departing from the spirit of Modernism. Among other things, it attempts to answer questions:
•	What are the compositional manipulations in the use of spolia in Greek Postwar Modernism and how does it interact with its normative principles?
•	Is there a relationship between the choice of spolia and the place of origin of the owners? If so, how is it interpreted?
Efficient detection of 1H, 15N correlations in hydrogen bonded low molecular catalyst–substrate intermediates without selective 15N-labelling
Creators: name: Scholtes, Christian Léonard
name: Ilgen, Julian
name: Gschwind, Ruth M.
Publisher: name: Universität Regensburg
Year: 2025
Subjects: subject: 540 Chemie

description: To date, SOFAST approaches have generally been limited to biomolecules. We present the applicability of SOFAST-HMQC techniques to small molecules in the slow-tumbling regime offering a time-efficient characterization of catalyst substrate hydrogen bonds with nitrogen at natural abundance. This extends NMR access to a broader range of catalyst substrate combinations.
A weighted cellular matrix-tree theorem, with applications to complete colorful and cubical complexes
Creators: name: Aalipour, Ghodratollah
name: Duval, Art M.
name: Kook, Woong
name: Lee, Kang-Ju
name: Martin, Jeremy L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C05, 05C50, 05E45

description: We present a version of the weighted cellular matrix-tree theorem that is suitable for calculating explicit generating functions for spanning trees of highly structured families of simplicial and cell complexes. We apply the result to give weighted generalizations of the tree enumeration formulas of Adin for complete colorful complexes, and of Duval, Klivans and Martin for skeleta of hypercubes. We investigate the latter further via a logarithmic generating function for weighted tree enumeration, and derive another tree-counting formula using the unsigned Euler characteristics of skeleta of a hypercube and the Crapo $β$-invariant of uniform matroids.
description: 22 pages, 2 figures. Sections 6 and 7 of previous version simplified and condensed. Final version to appear in J. Combin. Theory Ser. A
Opposite Sign Kloosterman Sum Zeta Function
Creators: name: Kiral, Eren Mehmet
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11L05, 11F66, 11F72, 11M36

description: We study the meromorphic continuation and the spectral expansion of the oppposite sign Kloosterman sum zeta function, $$(2π\sqrt{mn})^{2s-1}\sum_{\ell=1}^\infty \frac{S(m,-n,\ell)}{\ell^{2s}}$$ for $m,n$ positive integers, to all $s \in \mathbb{C}$. There are poles of the function corresponding to zeros of the Riemann zeta function and the spectral parameters of Maass forms. The analytic properties of this function are rather delicate. It turns out that the spectral expansion of the zeta function converges only in a left half-plane, disjoint from the region of absolute convergence of the Dirichlet series, even though they both are analytic expressions of the same meromorphic function on the entire complex plane.
description: 23 pages
Garcinia exigua Nazre 2018, sp. nov.
Creators: name: Nazre, M.
name: Newman, M. F.
name: Pennington, R. T.
name: Middleton, D. J.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Clusiaceae
Garcinia
Garcinia exigua

description: 5. Garcinia exigua Nazre, sp. nov.
 Garciniae nitidae similis sed foliis multo minoribus 0.8–2.1 × 0.3–1 cm (non 5–8.5 × 2.9–3.8 cm), fructibus minoribus (9.5–10.5 × 8.5–11 mm) stigmate sessili vel subsessili (non ad 10 mm elongata) valde recedit.
 Type:— MALAYSIA Borneo, Sarawak, Bintulu, Buan Forest Reserve, 18 September 1972, Paul Chai S 31750 (Holotype: SAR!; isotype: L!). [Figure 10].
 Tree to 20 m tall. Bole with dark brown, flaking, smooth and dippled bark; inner bark reddish. Exudate yellow. Twigs angled, stout, finely wrinkled longitudinally when dry, dark brown to pale brownish green, sometimes with a very small leaf-like terminal bud. Petiole finely transversely striate, dark brown or pale brown, to 0.5 cm long. Lamina thickly leathery, pale brown or greenish brown, shiny above, elliptic, 0.8–2.1 × 0.3–1 cm, apex acute or bluntly acuminate, base acute to cuneate; midrib raised above and below; margin entire and finely revolute; secondary veins very faint to nearly invisible above, fine and inconspicuous below, brochidodromous; tertiary veins invisible. Glands clearly visible below, fine and slightly raised above and raised below, arranged in dark grey-black to greenish interrupted wavy lines, running nearly parallel to the midrib. Inflorescences probably terminal. Male flowers not seen. Female flowers not seen. Fruit globose or ellipsoid, shiny green turning yellow, wall smooth with fine longitudinal striae, dark maroon to brown, small, 9.5–10.5 × 8.5–11 mm; stigma sessile or slightly raised, flattened, discoid or convex, weakly 4-lobed or crenate, black rugose, to 4.5 mm across; with four persistent leathery sepals; seeds not known.
 Etymology:—Latin, from the small size of all parts in the specimens.
 Distribution and Habitat:—Rare and endemic species in Borneo, only represented from three localities in lowland and hill forest in Sarawak and Brunei.
 Taxonomic Notes:—The fruits and leaves closely resemble those of G. nitida Pierre except that they are smaller.
 Additional specimens examined:— MALAYSIA. Borneo: Sarawak: Mulu National Park, Ubong, Sungai Matong, 11 November 1990, Yii & Runi Pungga S57293 (K!, SAR!), 19 November 1990, Yii & Runi Pungga S61132 (K!, SAR!).
 BRUNEI: Temburong: Ulu Belalong, Ulu Belalong, 22 January 1994, Coode, Dransfield, Kirkup & Idris 7886 (A!).
description: Published as part of Nazre, M., Newman, M. F., Pennington, R. T. & Middleton, D. J., 2018, Taxonomic Revision of Garcinia Section Garcinia (Clusiaceae), pp. 1-52 in Phytotaxa 373 (1) on page 28, DOI: 10.11646/phytotaxa.373.1.1, http://zenodo.org/record/13727567
Generation of stable entanglement between two cavity mirrors by squeezed-reservoir engineering
Creators: name: Yang, Chun-Jie
name: An, Jun-Hong
name: Yang, Wanli
name: Li, Yong
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The generation of quantum entanglement of macroscopic or mesoscopic bodies in mechanical motion is generally bounded by the thermal fluctuation exerted by their environments. Here we propose a scheme to establish stationary entanglement between two mechanically oscillating mirrors of a cavity. It is revealed that, by applying a broadband squeezed laser acting as a squeezed-vacuum reservoir to the cavity, a stable entanglement between the mechanical mirrors can be generated. Using the adiabatic elimination and master equation methods, we analytically find that the generated entanglement is essentially determined by the squeezing of the relative momentum of the mechanical mirrors, which is transferred from the squeezed reservoir through the cavity. Numerical verification indicates that our scheme is within the present experimental state of the art of optomechanics.
description: 9 pages, 6 figures
Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation
Creators: name: Ding, Yanhua
name: Cheng, Genhong
name: Xu, Fengchao
name: Tan, Guangyun
name: Su, Lishan
name: Yi, Zhaohong
name: Niu, Junqi
name: Wang, Xiaosong
name: Zhang, Hong
name: Song, Hongxiao
name: Li, Feng
name: Du, Peishuang
name: Aliyari, Roghiyh
name: Qin, F. Xiao-Feng
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: To understand the molecular mechanisms that
mediate the anti-hepatitis B virus (HBV) effect
of interferon (IFN) therapy, we conduct highthroughput
bimolecular fluorescence complementation
screening to identify potential physical
interactions between the HBx protein and 145 IFNstimulated
genes (ISGs). Seven HBx-interacting
ISGs have consistent and significant inhibitory effects
on HBV replication, among which TRIM5g suppresses
HBV replication by promoting K48-linked
ubiquitination and degradation of the HBx protein
on the K95 ubiquitin site. The B-Box domain of
TRIM5g under overexpression conditions is sufficient
to trigger HBx degradation and is responsible
both for interacting with HBx and recruiting
TRIM31, which is an ubiquitin ligase that triggers
HBx ubiquitination. High expression levels of
TRIM5g in IFN-a-treated HBV patients might indicate
a better therapeutic effect. Thus, our studies identify
a crucial role for TRIM5g and TRIM31 in promoting
HBx degradation, which may facilitate the development
of therapeutic agents for the treatment of patients
with IFN-resistant HBV infection.
The Influence of Spatial Resolution on Nonlinear Force-Free Modeling
Creators: name: DeRosa, M. L.
name: Wheatland, M. S.
name: Leka, K. D.
name: Barnes, G.
name: Amari, T.
name: Canou, A.
name: Gilchrist, S. A.
name: Thalmann, J. K.
name: Valori, G.
name: Wiegelmann, T.
name: Schrijver, C. J.
name: Malanushenko, A.
name: Sun, X.
name: Régnier, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The nonlinear force-free field (NLFFF) model is often used to describe the solar coronal magnetic field, however a series of earlier studies revealed difficulties in the numerical solution of the model in application to photospheric boundary data. We investigate the sensitivity of the modeling to the spatial resolution of the boundary data, by applying multiple codes that numerically solve the NLFFF model to a sequence of vector magnetogram data at different resolutions, prepared from a single Hinode/SOT-SP scan of NOAA Active Region 10978 on 2007 December 13. We analyze the resulting energies and relative magnetic helicities, employ a Helmholtz decomposition to characterize divergence errors, and quantify changes made by the codes to the vector magnetogram boundary data in order to be compatible with the force-free model. This study shows that NLFFF modeling results depend quantitatively on the spatial resolution of the input boundary data, and that using more highly resolved boundary data yields more self-consistent results. The free energies of the resulting solutions generally trend higher with increasing resolution, while relative magnetic helicity values vary significantly between resolutions for all methods. All methods require changing the horizontal components, and for some methods also the vertical components, of the vector magnetogram boundary field in excess of nominal uncertainties in the data. The solutions produced by the various methods are significantly different at each resolution level. We continue to recommend verifying agreement between the modeled field lines and corresponding coronal loop images before any NLFFF model is used in a scientific setting.
description: Accepted to ApJ; comments/corrections to this article are welcome via e-mail, even after publication