cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Mechanics of airflow in human inhalation
Creators: name: Bates, Alister
Publisher: name: Imperial College London
Year: 2014

description: The mechanics of airflow in the large airways during inspiration affects important physiological functions such as ventilation, olfaction, heat exchange and mass transfer. The behaviour of the airflow is important not only for healthcare applications including diagnosis, intervention planning and assessment, but for inhalation toxicology. This research aims to further the understanding of human nasal physiology through computational modelling. Specifically, the effects of transient inhalation conditions on flow dynamics and transport were characterised and the changes in flow behaviour in response to certain pathologies quantified. The key findings can be summarised as follows: Firstly, the time scales for airflow in the large airways have been identified and the initial flow patterns revealed. Three phases in the temporal behaviour of the flow were identified (flow initiation, quasi-equilibrium and decay). The duration of each phase differs depending on the quantity of interest. Flow in the nose was characterised as transitional, whilst in parts of the descending airways it is turbulent, particularly in the faster moving regions around the jets which may occur in the pharynx, larynx and at the superior end of the trachea. The bulk of the flow is biased to fill only certain regions of the airways, whilst other regions carry little flow, due to features upstream. Analysis of cross-sectional images provided by medical imaging does not necessarily provide a representative view of the area available to the flow. Various scalar species were employed to represent the fate of nanoparticles and gaseous species within the airways. Only species with high diffusion rates exhibited significant absorption at the airway walls. Airway pathologies often cause changes to the geometry of the airway. One such pathology, the goitre, was found to curve the trachea and in some cases cause constriction. Both these geometric changes were found to increase the pressure loss and energy required to drive flow through the trachea. Furthermore, the flow in pathological cases was more disturbed. High resolution simulations have been used to address these topics and the scales simulated have been analysed in terms of the smallest features possible in the flow to determine their fidelity.
Recent Study on Development and Validation of Loperamide Hydrochloride Tablet Analysis Method with Absorbance and Area under Curve Methods Spectrophotometrically
Creators: name: Harrizul Rivai
name: Puspita, Renny
name: Sesry Misfadhila
Publisher: name: Zenodo
Year: 2021
Subjects: Loperamide hydrochloride
absorbance method
area under the curve method
spectrophotometry
development
validation
analysis

description: Development and validation of loperamide hydrochloride tablet method of analysis have been done by using the absorbance method and area under the curve method. This study used methanol and hydrochloric acid 0.1 N (9:1) as the best solvent with maximum absorption at wavelength 259.00 nm. The linearity of loperamide hydrochloride was obtained in the concentration range 200-600 ppm with a correlation coefficient value with the absorbance method and the areas under the curve method were 0.9998 and 0.9865, respectively. The results showed that the levels of loperamide hydrochloride in generic tablets obtained by absorbance method and the area under the curve method were 105.71% and 96.20%, respectively. The results of determination of loperamide levels in tablets of trademark obtained by absorbance method and the area under the curve method were 102.85% and 98.57%, respectively. The level of both samples met the requirements of Pharmacopoeia Indonesia edition V that is 90% -110%. The analysis of loperamide hydrochloride in tablets by ultraviolet-visible spectrophotometry by absorbance method is valid while the area under the curve method is invalid for analysis of loperamide hydrochloride in tablets.
Density Response from Kinetic Theory and Time Dependent Density Functional Theory for Matter Under Extreme Conditions
Creators: name: Dufty, James
name: Luo, Kai
name: Trickey, S. B.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The density linear response function for an inhomogeneous system of electrons in equilibrium with an array of fixed ions is considered. Two routes to its evaluation for extreme conditions (e.g., warm dense matter) are considered. The first is from a recently developed short-time kinetic equation; the second is from time-dependent density functional theory (tdDFT). The result from the latter approach agrees with that from kinetic theory in the "adiabatic approximation", providing support and context for each. Both provide a connection to the phenomenological Kubo-Greenwood method for calculating transport properties. A brief proof of the van Leeuwen theorem (an essential underpinning of tdDFT) extended to the mixed states of equilibrium ensembles is given.
description: 21 pages
Additional file 6 of Absence of evidence for the conservation outcomes of systematic conservation planning around the globe: a systematic map
Creators: name: McIntosh, Emma
name: Chapman, Sarah
name: Kearney, Stephen
name: Williams, Brooke
name: Althor, Glenn
name: Thorn, Jessica
name: Pressey, Robert
name: McKinnon, Madeleine
name: Grenyer, Richard
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Additional file 6. Review articles excluded at full-text screening.
Security and Privacy Analyses of Internet of Things Children's Toys
Creators: name: Chu, Gordon
name: Apthorpe, Noah
name: Feamster, Nick
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cryptography and Security (cs.CR)
subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: This paper investigates the security and privacy of Internet-connected children's smart toys through case studies of three commercially-available products. We conduct network and application vulnerability analyses of each toy using static and dynamic analysis techniques, including application binary decompilation and network monitoring. We discover several publicly undisclosed vulnerabilities that violate the Children's Online Privacy Protection Rule (COPPA) as well as the toys' individual privacy policies. These vulnerabilities, especially security flaws in network communications with first-party servers, are indicative of a disconnect between many IoT toy developers and security and privacy best practices despite increased attention to Internet-connected toy hacking risks.
description: 8 pages, 8 figures; publication version
Development of silver catalysts for the heterocyclization reactions of alakynes
Creators: name: Wong, Hui Lin Valerie
Publisher: name: Imperial College London
Year: 2014

description: This PhD thesis describes work undertaken to develop efficient silver(I) catalysts for the intramolecular reactions of alkynes with nitrogen and oxygen containing nucleophiles for the synthesis of heterocycles. The introductory chapter provides an overview of recent advances in silver-catalyzed heterofunctionalization reactions of alkynes, with a focus on reactions involving C-N and C-O bond formations. A summary of the catalytic applicat ions of silver(I) NHC catalysts in the literature, which will be explored in Chapter 4, is also provided. Chapter 2 begins with the screening of silver salts as catalysts for the intramolecular hydroamination of alkynes with trichloroacetimidates. A strong counteranion effect on selectivity was observed. The impact of employing silver(I) complexes with variety of P- and N- donor ligands on catalytic activity was also explored, where pyridine-ligated silve r salts showed superior activity and selectivity. Reaction optimization was undertaken, and 1-bromoalkyne substrates were effectively cyclized with catalytic loadings as low as 1 mol%. Chapter 3, the application of the pyridine-ligated silver salts developed in Chapter 2 as catalysts for the cycloisomerization of propargyl amides is described. A broader substrate scope was observed compared to the previously reported AgSbF6 catalyst and a mechanism for the reaction is proposed based on experimental observations. In Chapter 4, the synthesis and characterization of a new class of silver(I) NHC carboxylate complexes are presented. The activity towards the cycloisomerization of propargyl amides was investigated, and they showed complementary reactivities compared to the pyridine-ligated silver catalysts in Chapter 3. In Chapter 5, an overall conclusion and future work are discussed. The last Chapter contains experimental procedures and characterization data of all the compounds synthesized during the course of this project.
Additional file 5 of Absence of evidence for the conservation outcomes of systematic conservation planning around the globe: a systematic map
Creators: name: McIntosh, Emma
name: Chapman, Sarah
name: Kearney, Stephen
name: Williams, Brooke
name: Althor, Glenn
name: Thorn, Jessica
name: Pressey, Robert
name: McKinnon, Madeleine
name: Grenyer, Richard
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Additional file 5. List of articles excluded at full-text stage, including reasons for their exclusion.
A new class of irreducible pentanomials for polynomial based multipliers in binary fields
Creators: name: Banegas, Gustavo
name: Custodio, Ricardo
name: Panario, Daniel
Publisher: name: arXiv
Year: 2018
Subjects: subject: Number Theory (math.NT)
subject: Cryptography and Security (cs.CR)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: We introduce a new class of irreducible pentanomials over $\mathbb{F}_2$ of the form $f(x) = x^{2b+c} + x^{b+c} + x^b + x^c + 1$. Let $m=2b+c$ and use $f$ to define the finite field extension of degree $m$. We give the exact number of operations required for computing the reduction modulo $f$. We also provide a multiplier based on Karatsuba algorithm in $\mathbb{F}_2[x]$ combined with our reduction process. We give the total cost of the multiplier and found that the bit-parallel multiplier defined by this new class of polynomials has improved XOR and AND complexity. Our multiplier has comparable time delay when compared to other multipliers based on Karatsuba algorithm.
Rondeletia americana Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Gentianales
Rubiaceae
Rondeletia
Rondeletia americana

description: Rondeletia americana, spec. nov.
1. Rondeletia foliis sessilibus.
 Rondeletia arborescens, tini facie. Plum. gen.15.
 Habitat in America . ♄
 Arbusculae Folia opposita, sessilia, lanceolata. Pedunculi communes solitarii, longissimi, nudi, apice formantes corymbum dichotomum; in cujus singula dichotomia. Flos sessilis, cum involucro diphyllo.
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 172, DOI: 10.5281/zenodo.3931989
title: Παιδοδοντιατρική - Εργαστηριακός οδηγός
Creators: name: Kotsanos, Nikolaos
name: Archakis, Aristeidis
Publisher: name: Kallipos, Open Academic Editions
Year: 2016
Subjects: ΕΡΓΑΣΤΗΡΙΑΚΗ ΑΣΚΗΣΗ - ΠΑΡΑΣΚΕΥΗ ΔΟΝΤΙΩΝ - ΠΡΟΚΑΤΑΣΚΕΥΑΣΜΕΝΕΣ ΣΤΕΦΑΝΕΣ
Laboratory Practice - Cavity Preparation - Preformed Metal Crowns

description: Σκοπός του βιβλίου είναι να περιγραφούν οι απαραίτητες θεωρητικές και τεχνικές γνώσεις που αφορούν την Παιδοδοντιατρική σε εργαστηριακό επίπεδο ή σε συνθήκες κλινικής προσομοίωσης, ώστε να χρησιμοποιηθούν για βελτίωση δεξιοτήτων σε επίπεδο αριστείας στην κλινική πράξη.
Στο σύγγραμμα αυτό περιγράφονται τα ακόλουθα:
1. Οι μορφολογικές και ιστολογικές διαφορές νεογιλών και μονίμων δοντιών και πώς αυτές επηρεάζουν τις παρασκευές κοιλότητας για έμφραξη με αμάλγαμα ή αισθητικά υλικά.
2. Τα οφέλη χρήσης του απομονωτήρα τόσο για τον ασθενή όσο και για τον οδοντίατρο. Τα απαραίτητα εργαλεία και υλικά για την απομόνωση. Οι διάφοροι τρόποι απομόνωσης. Τα στάδια απομόνωσης. Τρόποι απομόνωσης για πρόσθια και οπίσθια δόντια.
3. Οι ενδείξεις εφαρμογής κάλυψης οπών και σχισμών (ΚΟΣ). Τα στάδια κλινικής εφαρμογής ΚΟΣ. Τα είδη υλικών ΚΟΣ. Συχνότητα επανεξετάσεων των ΚΟΣ. Εφαρμογή ΚΟΣ σε νεογιλά και μόνιμα δόντια.
4. Οι ενδείξεις εφαρμογής προληπτικών εμφράξεων σύνθετης ρητίνης και τα τα στάδια της κλινικής εφαρμογής τους.
5. Οι μέθοδοι παρασκευής κοιλοτήτων Ιης, ΙΙης, ΙΙΙης και Vης ομάδας σε νεογιλά δόντια για εμφράξεις με σύνθετη ρητίνη, ρητινωδώς τροποποιημένη υαλοιονομερής κονία και αμάλγαμα.
6. Οι ενδείξεις και οι μέθοδοι τοποθέτησης προκατασκευασμένων ανοξείδωτων στεφανών καθώς και αισθητικών στεφανών στα νεογιλά δόντια.
7. Οι ενδείξεις και τα στάδια πολφοτομής στα νεογιλά δόντια.
8. Οι προϋποθέσεις ενός σωστού νάρθηκα ακινητοποίησης μετά από οδοντικό τραύμα, οι διάφορες μέθοδοι ακινητοποίησης, τα στάδια εφαρμογής νάρθηκα ακινητοποίησης.
9. Οι ενδείξεις εφαρμογής των πάγιων και κινητών μηχανημάτων διατήρησης και επανάκτησης χώρου και τα στάδια κατασκευής τους (δακτυλίου με συρμάτινη αγκύλη, γλωσσικού τόξου, διυπερώιου τόξου, υπερώιας πλάκας με ελατήρια, εξελίκτρα κλπ).
Rondeletia americana Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Gentianales
Rubiaceae
Rondeletia
Rondeletia americana

description: Rondeletia americana Linnaeus, Species Plantarum 1: 172. 1753.
"Habitat in America." RCN: 1351.
Lectotype (Howard, Fl. Lesser Antilles 6: 455. 1989): [icon] " Rondeletia foliis sessilibus " in Plumier in Burman, Pl. Amer: 237, t. 242, f. 1. 1760.
Generitype of Rondeletia Linnaeus (vide Hitchcock, Prop. Brit. Bot.: 131. 1929).
Current name: Rondeletia americana L. (Rubiaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 798, DOI: 10.5281/zenodo.291971
High strain rate testing of metals
Creators: name: Worley, Alexander
Publisher: name: Imperial College London
Year: 2015

description: Tensile and compressive tests were carried out on a selection of metals of interest in engineering applications. These metals were tested at a range of strain rates and temperatures with the aim of calibrating material constitutive models for the simulation of full scale structures in industry. In order to validate these models for use under conditions of strain rates exceeding those imposed by the tests which were used for calibration of the models, both tensile and compressive ballistic tests were carried out. A ball on plate experiment was used to compare the deformation predicted under the tensile conditions, including high speed speckle DIC for out of plane displacement measurement. A bespoke gas gun for the purpose of carrying out Taylor impact tests on samples of the same materials was designed and installed at Imperial College. The gas gun was used to carry out Taylor tests which were also lmed at high speed for comparison with tests simulated under compressive loading. Furthermore, post-impact samples were sectioned so that a hardness survey could be carried out across the internal section of a sample. These data were combined to produce a map indicative of plastic strain within the sample and used as another validation tool for the model using the Taylor test. It was found that the Johnson-Cook model was not su cient to represent the materials at the conditions under study. Both the ball on plate and Taylor test comparisons revealed the discrepancy between the model and the actual material response. Furthermore, the hardness map of the post test Taylor cylinders revealed that a volume within the cylinder at the base of the bulge experienced less hardening than the volume around it, consistent with predictions made from the nite element analysis.
INSON HUQUQLARI TIZIMINING SHAKLLANISHIDA NYURENBERG HARBIY TRIBUNALI NIZOMI PRINSIPLARINING AHAMIYATI
Creators: name: Ashurova, Mohlaroy
Publisher: name: Zenodo
Year: 2024

description: Nyurnberg mahkamasi, keyin esa Tokiodagi sud jarayoni xalqaro huquqning rivojlanishidagi muhim bosqichdir. Yangi tarixda birinchi marta mag‘lubiyatga uchragan davlat rahbarlariga alohida insonlar va xalqlar o‘rtasida tinch-totuv yashash asoslariga xavf soladigan og‘ir jinoyatlar: tinchlikka qarshi jinoyatlar, urush jinoyatlari va insoniyatga qarshi jinoyatlar sodir etilganligi uchun ayblov e’lon qilindi. Germaniyaning tinchlikka qarshi jinoyatlarni hech qanday qonuniy asosga ega emasligi ochiqlandi. Biroq, harbiy jinoyatlar va insoniyatga qarshi jinoyatlar bo'yicha ayblov xulosasiga hech qanday asosli e'tiroz bildirish mumkin emas edi.
Gravitational Microlensing by Random Motion of Stars: Analysis of Light Curves
Creators: name: Wambsganss, Joachim
name: Kundic, Tomislav
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a quantitative analysis of the effect of microlensing caused by random motion of individual stars in the galaxy which is lensing a background quasar. We calculate a large number of magnification patterns for positions of the stars slightly offset from one frame to the next, and in this way obtain light curves for fixed quasar and galaxy positions, only due to the change in the relative star positions. These light curves are analyzed to identify micro- lensing events, which are classified according to height, duration, and slope. We find that microlensing events produced by random motion of stars are shorter, steeper, and more frequent than bulk motion events. This difference is caused by the fact that in the case of random motion, caustics can move with arbitrarily high velocity, producing very short events. An accompanying video illustrates these results. For three different values of the surface mass density kappa, it shows time sequences of 1000 magnification patterns for slowly changing lens positions, together with the positions and velocity vectors of the microlensing stars. Short sequences of the video are available as MPEG movie by anonymous ftp at ftp://astro.princeton.edu/jkw/microlensing/moving_stars .
description: 20 pages of uuencoded compressed Postscript file, including 8 (out of 10) figures; accepted for publication in ApJ, Sept.1 1995
Nuclear Reactions Rates Governing the Nucleosynthesis of Ti44
Creators: name: The, L. -S.
name: Clayton, D. D.
name: Jin, L.
name: Meyer, B. S.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Large excesses of Ca44 in certain presolar graphite and silicon carbide grains give strong evidence for Ti44 production in supernovae. Furthermore, recent detection of the Ti44 gamma-line from the Cas A SNR by CGRO/COMPTEL shows that radioactive Ti44 is produced in supernovae. These make the Ti44 abundance an observable diagnostic of supernovae. Through use of a nuclear reaction network, we have systematically varied reaction rates and groups of reaction rates to experimentally identify those that govern Ti44 abundance in core-collapse supernova nucleosynthesis. We survey the nuclear-rate dependence by repeated calculations of the identical adiabatic expansion, with peak temperature and density chosen to be 5.5xE9 K and 1E7 g/cc, respectively, to approximate the conditions in detailed supernova models. We find that, for equal total numbers of neutrons and protons (eta=0), Ti44 production is most sensitive to the following reaction rates: Ti44(alpha,p)V47, alpha(2alpha,gamma)C12, Ti44(alpha,gamma)Cr48, V45(p,gamma)Cr46. We tabulate the most sensitive reactions in order of their importance to the Ti44 production near the standard values of currently accepted cross-sections, at both reduced reaction rate (0.01X) and at increased reaction rate (100X) relative to their standard values. Although most reactions retain their importance for eta > 0, that of V45(p,gamma)Cr46 drops rapidly for eta >= 0.0004. Other reactions assume greater significance at greater neutron excess: C12(alpha,gamma)O16, Ca40(alpha,gamma)Ti44, Al27(alpha,n)P30, Si30(alpha,n)S33. Because many of these rates are unknown experimentally, our results suggest the most important targets for future cross section measurements governing the value of this observable abundance.
description: 37 pages, LaTex, 17 figures, 8 tables
Towards spatial and temporal analysis of facial expressions in 3D data
Creators: name: Rajamanoharan, Georgia
Publisher: name: Imperial College London
Year: 2014

description: Facial expressions are one of the most important means for communication of emotions and meaning. They are used to clarify and give emphasis, to express intentions, and form a crucial part of any human interaction. The ability to automatically recognise and analyse expressions could therefore prove to be vital in human behaviour understanding, which has applications in a number of areas such as psychology, medicine and security. 3D and 4D (3D+time) facial expression analysis is an expanding field, providing the ability to deal with problems inherent to 2D images, such as out-of-plane motion, head pose, and lighting and illumination issues. Analysis of data of this kind requires extending successful approaches applied to the 2D problem, as well as the development of new techniques. The introduction of recent new databases containing appropriate expression data, recorded in 3D or 4D, has allowed research into this exciting area for the first time. This thesis develops a number of techniques, both in 2D and 3D, that build towards a complete system for analysis of 4D expressions. Suitable feature types, designed by employing binary pattern methods, are developed for analysis of 3D facial geometry data. The full dynamics of 4D expressions are modelled, through a system reliant on motion-based features, to demonstrate how the different components of the expression (neutral-onset-apex-offset) can be distinguished and harnessed. Further, the spatial structure of expressions is harnessed to improve expression component intensity estimation in 2D videos. Finally, it is discussed how this latter step could be extended to 3D facial expression analysis, and also combined with temporal analysis. Thus, it is demonstrated that both spatial and temporal information, when combined with appropriate 3D features, is critical in analysis of 4D expression data.
title: ADCO, Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Cart. 172 (11 H 69), 115 folios, f. 0008
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi

description: Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Archives départementales de la Côte-d'Or, Cart. 172 (11 H 69), 115 folios, f. 0008, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Archives départementales de la Côte-d'Or, Cart. 172 (11 H 69), 115 folios, f. 0008, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
The baseline instantaneous wave-free ratio as an index of coronary disease severity: relationship with fractional flow reserve and coronary flow reserve
Creators: name: Petraco Da Cunha, Ricardo
Publisher: name: Imperial College London
Year: 2014

description: Over the last 30 years the development of invasive methods to directly measure the haemodynamic impact of individual coronary stenoses on blood flow has enabled the identification of vessel-specific and lesion-specific ischaemia. Fractional flow reserve (FFR) is the most commonly used technique, largely due to the simplification brought by its pressure-only methodology. Despite the evidence accumulated demonstrating the benefits of FFR-guided decisions, its adoption remains low worldwide (6-8%) and a large proportion of patients with coronary artery disease (CAD) still undergo percutaneous interventions without any objective evidence of myocardial ischaemia. This is partly due to FFR’s reliance on the induction of coronary hyperaemia, a methodological step which adds time, cost and inconvenience for patients and clinicians. Recently, our group presented a novel invasive pressure-only methodology, the instantaneous wave-free ratio (iFR), which differs from FFR as it can be calculated at baseline, without the need for vasodilator administration. In its initial validation studies, iFR demonstrated a close diagnostic agreement with FFR and with invasive coronary flow. In this thesis, I will present a series of studies which aim to further evaluate the utility of iFR as an index coronary stenosis severity. Firstly, I will explore its diagnostic relationship with FFR in details and present a novel methodology to measure classification agreement between methods of clinical measurement. Secondly, I will evaluate the merits of utilising iFR and FFR in a common diagnostic pathway and quantify the potential benefits of such a strategy to spare patients from the need for vasodilator administration. Finally, I will investigate the relationship between pressure-only indices (iFR and FFR) and coronary flow reserve, an extensively validated marker of prognosis in coronary disease.
MOESM6 of Absence of evidence for the conservation outcomes of systematic conservation planning around the globe: a systematic map
Creators: name: McIntosh, Emma
name: Chapman, Sarah
name: Kearney, Stephen
name: Williams, Brooke
name: Althor, Glenn
name: Thorn, Jessica
name: Pressey, Robert
name: McKinnon, Madeleine
name: Grenyer, Richard
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Cell Biology
Science Policy
Computational Biology

description: Additional file 6. Review articles excluded at full-text screening.
title: ADCO, Grènetier de Cîteaux : comptes (1499-1503) (11 H 1173), f. 00180
Creators: name: de la Côte-d'Or, Archives départementales
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes

description: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173), f. 00180, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Possible Extragalactic Sources of the Highest Energy Cosmic Rays
Creators: name: Rachen, Joerg P.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We give an outline of possible extragalactic explanations of the highest energy cosmic ray events. We give a classification of the possible particles which could have caused the events and try to find suitable sources for each class. In contrast to some previous investigations of other authors, we find a possible candidate of a local FR-II radio galaxy close to the Fly's Eye event, and less powerful active galaxies close to the AGASA event. We also note the interesting coincidence that we have strong, distant quasars inside the arrival direction error regimes of both the Fly's Eye and AGASA event. We briefly discuss the consequences for the cosmic ray spectrum and composition at highest energies, which could be investigated by future experiments.
description: Contributed paper to the 17th Texas Symposium, Munich, Dec 1994; 4 pages, uudecoded compressed PostScript file, figures included.
Droplet-based separation tools for multidimensional biological separations
Creators: name: Thamsumet, Nuchutha
Publisher: name: Imperial College London
Year: 2015

description: Proteins have been extensively studied over the last decade as comprehensive understanding of the proteome can definitely lead to the discovery of novel biomarkers, early-stage disease diagnoses and the development of diagnostic tools and novel drug therapies. One of the crucial and fundamental processes in protein analysis is protein separation, which is usually performed as multidimensional separations to achieve high resolution and high peak capacity. However, high performance analyses are difficult to achieve due to the challenges involved in efficiently integrating different dimensions. In this work, we present the development of a microfluidic device for the effective transfer of protein droplets into the second separation dimension. Consequently, the device provides a stable, reproducible, easy to operate, portable and flexible system to connect a first dimension separation to the downstream second dimension analysis via droplets. The droplets act to preserve the resolution during transfer between separation techniques. In summary, a fluorescently labeled protein ladder serving as a representative of proteins separated from the first dimension is compartmentalized into droplets using the robotic droplet generator. These protein droplets are then transferred via the interfacing microdevice into the second dimension where the released proteins are further separated using capillary gel electrophoresis. Herein, several designs of interfacing microdevices were evaluated for the successful transfer of droplet contents (droplet injection) into the second dimension. The buffer for capillary gel electrophoresis was developed to achieve high-speed and high-resolution separations of proteins in droplet-based injection format. Several fluorescent dyes were also examined for protein labeling to achieve high fluorescent intensities necessary when using this droplet format. Successful droplet-based separation of proteins necessitates the seamless integration of all the developed components. This has been demonstrated here. This interface automates the oil depletion process, minimizes dead volume, prevents dispersion of analyte bands and reduces sample loss at the interface between separation dimensions. Furthermore, optimization of the entire system used in conjunction with the interfacing microdevice provided for ease of operation and more efficient droplet injections. Moreover, droplet injection into parallel separation channels was achieved, highlighting the interfaces capacity for high-throughput analyses.
The Supernova-Gamma Ray Burst Connection
Creators: name: Wang, Lifan
name: Wheeler, J. Craig
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Supernovae 1998bw and its corresponding relativistically expanding radio source are coincident with the \grb source GRB 980425. We show that of six recent SN Ib/c for which an outburst epoch can be estimated with some reliability, four have radio outbursts and all are correlated in time and space with BATSE \grbs. The joint probability of all six correlations is 1.5$\times10^{-5}$. No such correlation exists for SN Ia and SN II. The \gr\ energy associated with the SN/GRB events is $\sim10^{46} - 10^{48}$ ergs if emitted isotropically. Economy of hypotheses leads us to propose that all \grbs are associated with supernovae and that the \grb events have a quasi-isotropic component that cannot be observed at cosmological distances and a strongly collimated and Doppler-boosted component that can only be seen if looking nearly along the collimation axis. Such collimation requires a high rate of occurrence perhaps consistent with a supernova rate. The collimated flow may be generated by core collapse to produce rotating, magnetized neutron stars. All core collapse events may produce such jets, but only the ones that occur in supernovae with small or missing hydrogen envelopes, Type Ib or Ic, can propagate into the interstellar medium and yield a visible \grb. We suggest that asymmetries in line profiles and spectropolarimetry of SN II and SN Ib/c, pulsar runaway velocities, soft \gr repeaters and \grbs are associated phenomena.
description: Submitted to ApJL on May 19, 1998. Revised on Jun 15, 1998
Reminiscences of T. Dale Alford 1970
Publisher: name: Columbia University
Year: 2020
Subjects: Legislators--United States
Physicians
African Americans--Segregation
School integration--Arkansas

description: Member of school board, Little Rock, Arkansas during integration crisis, 1958; one-term congressman elected in 1958 as a result of integration crisis; author of THE CASE OF THE SLEEPING PEOPLE
Additional file 1 of Assembly and comparative analysis of the complete mitochondrial genome of Ilex metabaptista (Aquifoliaceae), a Chinese endemic species with a narrow distribution
Creators: name: Zhou, Peng
name: Zhang, Qiang
name: Li, Fei
name: Huang, Jing
name: Zhang, Min
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Summary of sequencing statistics.
Stabilizing quantum coherence against pure dephasing in the presence of quantum feedback at finite temperature
Creators: name: Német, Nikolett
name: Parkins, Scott
name: Knorr, Andreas
name: Carmele, Alexander
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A general formalism to describe the dynamics of quantum emitters in structured reservoirs is introduced. As an application, we investigate the optical coherence of an atom-like emitter diagonally coupled via a link-boson to a structured bosonic reservoir and obtain unconventional dephasing dynamics due to non-Markovian quantum feedback for different temperatures. For a two-level emitter embedded in a phonon cavity preservation of finite coherence is predicted up to room temperature.
description: 12 pages, 4+2 figures
Front-tracking finite element methods for a void electro-stress migration problem
Creators: name: Sacconi, Andrea
Publisher: name: Imperial College London
Year: 2015

description: Continued research in electronic engineering technology has led to a miniaturisation of integrated circuits. Further reduction in the dimensions of the interconnects is impeded by the presence of small cracks or voids. Subject to high current and elastic stress, voids tend to drift and change shape in the interconnect, leading to a potential mechanical failure of the system. This thesis investigates the temporal evolution of voids moving along conductors, in the presence of surface diffusion, electric loading and elastic stress. We simulate a bulk-interface coupled system, with a moving interface governed by a fourth-order geometric evolution equation and a bulk where the electric potential and the displacement field are computed. We first give a general overview about geometric evolution equations, which define the motion of a hypersurface by prescribing its normal velocity in terms of geometric quantities. We briefly describe the three main approaches that have been proposed in the literature to solve numerically this class of equations, namely parametric approach, level set approach and phase field approach. We then present in detail two methods from the parametric approach category for the void electro-stress migration problem. We first introduce an unfitted method, where bulk and interface grids are totally independent, i.e. no topological compatibility between the two grids has to be enforced over time. We then discuss a fitted method, where the interface grid is at all times part of the boundary of the bulk grid. A detailed analysis, in terms of existence and uniqueness of the finite element solutions, experimental order of convergence (when the exact solution to the free boundary problem is known) and coupling operations (e.g., smoothing/remeshing of the grids, intersection between elements of the two grids), is carried out for both approaches. Several numerical simulations, both two- and three-dimensional, are performed in order to test the accuracy of the methods.
Evolution of the Supercluster-Void Network
Creators: name: Frisch, P.
name: Einasto, J.
name: Einasto, M.
name: Freudling, W.
name: Fricke, K. J.
name: Gramann, M.
name: Saar, V.
name: Toomet, O.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Recently, the observed cellular nature of the large-scale structure of the Universe with its quasi-regular pattern of superclusters and voids has been pointed out by several authors. In this paper, we investigate properties of the initial power spectrum which lead to prediction of structure consistent with these observations.For this purpose, we analyze the evolution of structure within four sets of 2- and 3-dimensional cosmological models, which differ in their initial power spectrum. The models include HDM and CDM models as well as double power-law models. We discuss in detail the impact of model parameters such as the large scale and small scale power and the position and height of the maxima of the power spectra on the predicted structure. The best agreement with observations was observed in the model with the Harrison-Zeldovich spectrum on large scales, a power index $n\approx -1.5$ on small scales, and a maximum of the power spectrum at $\approx 130$~\Mpc. In this model the distribution of masses of clusters and superclusters, the correlation function of clusters, and the void distribution reproduce well the respective observed distributions. We also investigated the dynamical evolution of the supercluster-void structure. The results show that the basic supercluster-void network is formed very early and is essentially given by initial conditions.
description: 18 Pages, uuencoded postscript, postscript figures are available on request or at http://www.uni-sw.gwdg.de/~pfrisch or anonymous ftp at ftp://eden.uni-sw.gwdg.de/incoming/pfrisch )
Complexity growth and shock wave geometry in AdS-Maxwell-power-Yang-Mills theory
Creators: name: Yaraie, Emad
name: Ghaffarnejad, Hossein
name: Farsam, Mohammad
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study effects of non-abelian gauge fields on the holographic characteristics for instance the evolution of computational complexity. To do so we choose Maxwell-power-Yang-Mills theory defined in the AdS space-time. Then we seek the impact of charge of the YM field on the complexity growth rate by using $complexity=action$ (CA) conjecture. We also investigate the spreading of perturbations near the horizon and the complexity growth rate in local shock wave geometry in presence of the YM charge. At last we check validity regime of Lloyd bound.
description: 18 pages, 2 Figures and improved with some additional sentences
MOESM5 of Absence of evidence for the conservation outcomes of systematic conservation planning around the globe: a systematic map
Creators: name: McIntosh, Emma
name: Chapman, Sarah
name: Kearney, Stephen
name: Williams, Brooke
name: Althor, Glenn
name: Thorn, Jessica
name: Pressey, Robert
name: McKinnon, Madeleine
name: Grenyer, Richard
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Cell Biology
Developmental Biology
Science Policy
Computational Biology

description: Additional file 5. List of articles excluded at full-text stage, including reasons for their exclusion.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Cart. 188 (11 H 73), f. 0288r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Archives départementales de la Côte-d'Or, Cart. 188 (11 H 73), f. 0288r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Archives départementales de la Côte-d'Or, Cart. 188 (11 H 73), f. 0288r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
title: Αναδιοργάνωση και μάνατζμεντ αλλαγών στις επιχειρήσεις
Creators: name: Georgopoulos, Antonios
Publisher: name: Kallipos, Open Academic Editions
Year: 2016
Subjects: ΣΤΡΑΤΗΓΙΚΗ ΕΤΑΙΡΕΙΩΝ
ΔΙΕΘΝΕΙΣ ΕΠΙΧΕΙΡΗΣΕΙΣ
ΕΠΙΒΙΩΣΗ ΕΠΙΧΕΙΡΗΣΕΩΝ
ΔΙΑΧΕΙΡΙΣΗ ΚΡΙΣΕΩΝ
ΣΥΓΧΩΝΕΥΣΕΙΣ & ΕΞΑΓΟΡΕΣ
ΕΠΙΔΟΣΗ ΕΠΙΧΕΙΡΗΣΕΩΝ
ΜΕΤΑΣΧΗΜΑΤΙΣΜΟΣ ΕΠΙΧΕΙΡΗΣΕΩΝ
Firm Strategy
International Firms
Firm Survival
Crisis Management
Mergers & Acquisitions
Firm Performance
Business Transformation

description: Το προτεινόμενο βιβλίο απευθύνεται στους προπτυχιακούς και μεταπτυχιακούς φοιτητές, στους ερευνητές, στους διδάσκοντες και σε όλους τους ειδικούς της διοίκησης, της οργάνωσης και της αναδιοργάνωσης επιχειρήσεων, δίνοντας έμφαση στην αναδιάρθρωση και το μετασχηματισμό των επιχειρηματικών δραστηριοτήτων, ο οποίος είναι απόρροια στρατηγικών εσωτερικών ή εξωτερικών αλλαγών του επιχειρηματικού περιβάλλοντος. Η όλη ανάλυση πραγματοποιείται έχοντας ως υπόβαθρο τη σκέψη ότι οι διαρκείς αλλαγές είναι σχεδόν η μόνη σταθερά στο σημερινό δυναμικό οικονομικο-κοινωνικό περιβάλλον.
Το βιβλίο αυτό φιλοδοξεί να προσφέρει όσο το δυνατόν μια σφαιρική προσέγγιση των παραγόντων των επιχειρηματικών αλλαγών, επικεντρώνοντας ταυτόχρονα στην ενδολεχή ανάλυση των σημαντικότερων εξ΄αυτών. Ειδικότερο, το βιβλίο προσεγίζει εννοιολογικά και αναπτύσσει μεθοδικά όρους και φαινόμενα αλλαγών που αφορούν:
- στον κύκλο ζωής των επιχειρήσεων
- στη διεθνοποίηση των επιχειρηματικών δραστηριοτήτων
- στην επιβιώση των επιχειρήσεων
- στην επιχειρηματική αποτυχία
- στις συγχωνεύσεις & εξαγορές
- στις ιδιωτικοποιήσεις
- στη διαχείριση κρίσεων
- στη διαχείριση εσωτερικών συγκρούσεων
MOESM1 of Pharmacological Rescue of the Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Detected by Use of a Novel Fluorescence Platform
Creators: name: Holleran, John
name: Glover, Matthew
name: Peters, Kathryn
name: Bertrand, Carol
name: Watkins, Simon
name: Jarvik, Jonathan
name: Frizzell, Raymond
Publisher: name: figshare
Year: 2012
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: Science Policy
subject: 60506 Virology

description: Supplementary material, approximately 423 KB.
Yet another fast multipole method without multipoles --- Pseudo-particle multipole method
Creators: name: Makino, Junichiro
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In this paper we describe a new approach to implement the O(N) fast multipole method and $O(N\log N)$ tree method, which uses pseudoparticles to express the potential field. The new method is similar to Anderson's method, which uses the values of potential at discrete points to represent the potential field. However, for the same expansion order the new method is more accurate and computationally efficient.
description: 14 pages, 2 figures
Role of newly discovered $Ξ_b(6227)^-$ for constructing excited bottom baryon family
Creators: name: Chen, Bing
name: Wei, Ke-Wei
name: Liu, Xiang
name: Zhang, Ailin
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Selecting the newly observed $Ξ_b(6227)^-$ by LHCb as a study example, we decode its inner structure by giving the mass spectrum analysis and the investigation of its two-body strong decay behaviors. Our result indicates that the $Ξ_b(6227)^-$ is a good candidate of the $P$-wave $Ξ_b^{\prime}$ state with $J^P=3/2^-$ or $5/2^-$. In addition, we further provide the information of the properties of the partners of the $Ξ_b(6227)^-$. These predicted states include three $2S$ states and the remaining $1P$ states in the bottom-strange baryon family. The calculated sizable Okubo-Zweig-Iizuka$-$allowed decay widths of these partners show that the experimental search for them becomes possible via LHCb. We have a reason to believe that the present study can be treated as a start point for constructing the highly excited bottom baryon spectroscopy.
description: 6 pages, 2 figures, 6 tables. Published version in PRD as a Rapid Communication