cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Optical and chemical control of the wettability of nanoporous photoswitchable films
Creators: name: Zhang, Zejun
name: Chen, Donghui
name: Mutruc, Dragos
name: Hecht, Stefan
name: Heinke, Lars
Publisher: name: Cambridge : Royal Society of Chemistry
Year: 2022
Subjects: subject: Azobenzene moiety
subject: Chemical controls
subject: Guest molecules
subject: Metal organic framework materials
subject: Nano-porous
subject: Nano-porous films
subject: Optical control
subject: Photo-switchable
subject: Photoswitching
subject: Thin-films
subject: 540

description: Wettability is a central surface property of functional thin films. Here, we present a nanoporous film made of an azobenzene-containing metal-organic framework material where the wettability is controlled by photoswitching of the fluorinated azobenzene moieties and by reversible incorporation of guest molecules with different polarities in the pores. Using both, the optical and the chemical stimuli, the water contact angle was modified over a wide range, from 23° to 97°.
Trends in Stage-Specific Incidence Rates for Urothelial Carcinoma of the Bladder in the United States: 1988 to 2006
Creators: name: Pruthi, Raj S.
name: Milowsky, Matthew I.
name: Smith, Angela B.
name: Kim, William Y.
name: Tyree, Seth
name: Kuo, Tzy Mey
name: Nielsen, Matthew E.
name: Millikan, Robert C.
name: Meyer, Anne Marie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Bladder cancer is notable for a striking heterogeneity of disease-specific risks. Among the approximately 75% of incident cases found to be superficial to the muscularis propria at the time of presentation (non-muscle-invasive bladder cancer), the risk of progression to the lethal phenotype of muscle-invasive disease is strongly associated with stage and grade of disease. Given the suggestion of an increasing percentage of low-risk cases in hospital-based registry data in recent years, the authors hypothesized that population-based data may reveal changes in the stage distribution of early-stage cases.
O PROCESSO AVALIATIVO SOMATIVO INTER-RELACIONADO COM O PROCESSO FORMATIVO E UTILIZAÇÃO DE TÉCNOLOGIAS DA INFORMAÇÃO PARA AUXÍLIO NA AVALIAÇÃO
Creators: name: Saulo Junior Ramos Lima
Publisher: name: Zenodo
Year: 2019
Subjects: Métodos de Avaliação
Avaliação no Ensino Superior
Docência
IES
TICs

description: No Brasil o processo avaliativo dá-se em sua maior parte pelo método somativo. Nos últimos dez anos, tem-se observado uma maior demanda da sociedade pela educação de nível superior, que até então, somente era percebida como importante para uma camada mais privilegiada. Posto isso, há grande preocupação com a formação desse cidadão dentro das IES, levando consequentemente a um estudo do processo avaliativo. Este trabalho de conclusão de curso inicia-se com uma busca teórica de métodos avaliativos, demonstrando de forma objetiva como as IES atualmente estão fazendo seus alunos percorrer um processo de formação que busca a simples aquiescência mínima de conteúdo para outorga de grau com vistas a satisfazer apenas a necessidade mercadológica. Objetiva identificar os métodos somativo e formativo e suas características, bem como críticas atinentes. Em segundo momento, demonstra-se o atual cenário da educação superior brasileira, e a interrelação envolvida entre o processo de ensino (professor – aluno, ensino – aprendizagem) e os demais agentes antecessores. Por fim, apresenta um processo interrelacionado de avaliação, não eliminando por completo o método utilizada pelas IES, até porque são partes da regulação normativa destas entidades, mas adaptando-o de maneira a torná-lo mais eficaz no processo de ensino-aprendizagem com a utilização de TICS.
Electronic Supplementary Material from Global patterns of thermal tolerances and vulnerability of endotherms to climate change remain robust irrespective of varying data suitability criteria.
Creators: name: Hof, Christian
name: Khaliq, Imran
name: Prinzinger, Roland
name: Böhning-Gaese, Katrin
name: Pfenninger, Markus
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Electronic Supplementary Material
The thermal stability of epitaxial GeSn layers
Creators: name: Zaumseil, P.
name: Hou, Y.
name: Schubert, M.A.
name: Von Den Driesch, N.
name: Stange, D.
name: Rainko, D.
name: Virgilio, M.
name: Buca, D.
name: Capellini, G.
Publisher: name: Melville, NY : AIP Publ.
Year: 2018
Subjects: subject: Diffusion process
subject: Direct observations
subject: Lattice relaxation
subject: Optical emissions
subject: Positive impacts
subject: Segregation process
subject: Sn contents
subject: 620
subject: 600

description: We report on the direct observation of lattice relaxation and Sn segregation of GeSn/Ge/Si heterostructures under annealing. We investigated strained and partially relaxed epi-layers with Sn content in the 5 at. %-12 at. % range. In relaxed samples, we observe a further strain relaxation followed by a sudden Sn segregation, resulting in the separation of a β-Sn phase. In pseudomorphic samples, a slower segregation process progressively leads to the accumulation of Sn at the surface only. The different behaviors are explained by the role of dislocations in the Sn diffusion process. The positive impact of annealing on optical emission is also discussed.
Practice adaptive reserve and colorectal cancer screening best practices at community health center clinics in 7 states: PAR and PCMH Best Practices
Creators: name: Pfeiffer, Debbie J.
name: Fernandez, Maria E.
name: Kegler, Michelle C.
name: Glenn, Beth A.
name: Tu, Shin Ping
name: Young, Vicki M.
name: Kimura, Amanda T.
name: Risendal, Betsy C.
name: Coombs, Letoynia J.
name: Williams, Rebecca S.
name: Friedman, Daniela B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Enhancing the capability of community health centers to implement best practices may mitigate health disparities. We investigated the association of Practice Adaptive Reserve (PAR) to implementation of Patient Centered Medical Home (PCMH) colorectal cancer (CRC) screening best practices (BPs) at community health center clinics in seven states.
Provider-based research networks and diffusion of surgical technologies among patients with early-stage kidney cancer: Surgical Advances and Research Networks
Creators: name: Kuo, Tzy Mey
name: Nielsen, Matthew E.
name: Smith, Angela B.
name: Meyer, Anne Marie
name: Wheeler, Stephanie B.
name: Tan, Hung Jui
name: Carpenter, William R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Provider-based research networks, such as the National Cancer Institute’s Community Clinical Oncology Program (CCOP), have been shown to facilitate the translation of evidence-based cancer care into clinical practice. As such, we compared utilization of laparoscopy and partial nephrectomy among patients with early-stage kidney cancer according to exposure to CCOP-affiliated providers.
Role of DLC-1, a tumor suppressor protein with RhoGAP activity, in regulation of the cytoskeleton and cell motility
Creators: name: Vigil, D.
name: Der, C. J.
name: Kim, T. Y.
name: Juliano, R. L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: DLC-1 was originally identified as a potential tumor suppressor. One of the key biochemical functions of DLC-1 is to serve as a GTPase activating protein (GAP) for members of the Rho family of GTPases, particularly Rho A-C and Cdc 42. Since these GTPases are critically involved in regulation of the cytoskeleton and cell migration, it seems clear that DLC-1 will also influence these processes. In this review we examine basic aspects of the actin cyoskeleton and how it relates to cell motility. We then delineate the characteristics of DLC-1 and other members of its family, and describe how they may have multiple effects on the regulation of cell polarity, actin organization, and cell migration.
title: Posterior fossa cysts and cyst-like malformations in paediatric population
Creators: name: Grigoryan, Marine
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: CNS
subject: Neuroradiology brain
subject: MR
subject: Diagnostic procedure
subject: eLearning
subject: Normal variants
subject: Congenital
subject: Cysts

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: 1 . To understand what posterior fossa cysts and cyst - like malformations are 2 . To recognize the radiological features and symptoms that correspond to each posterior fossa cysts and cyst - like malformations 3 . To describe the main differential...
The transcriptomics of de novo androgen biosynthesis in prostate cancer cells following androgen reduction
Creators: name: Mohler, James L.
name: Wu, Yue
name: Ip, Clement
name: Cheng, Jinrong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The progression of prostate cancer to the castration-recurrent phenotype remains a major problem medically. The present study examined the transcriptomics of de novo androgen synthesis as a potential mechanism to escape from dependence on circulating androgen. VCaP, LNCaP and LAPC4 cells were acclimated to 1 nM testosterone for 5 generations before subjecting them to a reduced level of 0.03 nM testosterone. Changes in gene expression were quantified using qRT-PCR. Analyses of the cholesterol biosynthesis pathway and the Δ4, Δ5 and backdoor steroidogenic pathways were carried out. VCaP cells showed no change in the transcriptome of cholesterol biosynthesis. However, several receptors for cholesterol transport were up-regulated. The Δ4 and Δ5 steroidogenic pathways, but not the backdoor pathway, were stimulated. Additionally, androgen receptor (AR) expression was increased. Taken together, the above changes might allow recovery of AR activity to a near normal level. In contrast, LNCaP cells showed only minimal adjustment in the transcriptome of steroidogenesis. LAPC4 cells were equally unresponsive to boosting the machinery of androgen production. In brief, our results suggest that the VCaP model is an appropriate model for further investigation of targeting the androgen-AR axis to block the emergence of castration-resistant prostate cancer.
title: Frequency of lipid-poor adrenal adenomas in abdominal magnetic resonance imaging examinations
Creators: name: Martins, Victor
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: CT
subject: MR
subject: Imaging sequences
subject: Cancer
subject: Neoplasia

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Given the paucity of data about the prevalence of LPAs on MR images, we performed this retrospective study in asymptomatic patients to assess the frequency of LPAs in consecutive abdominal MR examinations over a 2-year...
Fundamental limits on the accuracy of demographic inference based on the sample frequency spectrum
Creators: name: Terhorst, Jonathan
name: Song, Yun S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Statistics Theory (math.ST)
subject: FOS: Biological sciences
subject: FOS: Mathematics

description: The sample frequency spectrum (SFS) of DNA sequences from a collection of individuals is a summary statistic which is commonly used for parametric inference in population genetics. Despite the popularity of SFS-based inference methods, currently little is known about the information-theoretic limit on the estimation accuracy as a function of sample size. Here, we show that using the SFS to estimate the size history of a population has a minimax error of at least $O(1/\log s)$, where $s$ is the number of independent segregating sites used in the analysis. This rate is exponentially worse than known convergence rates for many classical estimation problems in statistics. Another surprising aspect of our theoretical bound is that it does not depend on the dimension of the SFS, which is related to the number of sampled individuals. This means that, for a fixed number $s$ of segregating sites considered, using more individuals does not help to reduce the minimax error bound. Our result pertains to populations that have experienced a bottleneck, and we argue that it can be expected to apply to many populations in nature.
description: 17 pages, 1 figure
Electronic Supplementary Material from Global patterns of thermal tolerances and vulnerability of endotherms to climate change remain robust irrespective of varying data suitability criteria
Creators: name: Hof, Christian
name: Khaliq, Imran
name: Prinzinger, Roland
name: Böhning-Gaese, Katrin
name: Pfenninger, Markus
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Electronic Supplementary Material
title: Determining Transverse Atlantal Ligament Integrity on Cervical CT in the Setting of an Acute C1 Burst Fracture
Creators: name: Fiester, Peter
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Neuroradiology spine
subject: Trauma
subject: CT
subject: MR
subject: Decision analysis
subject: Trauma

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Burst fractures of the C1 vertebrae – commonly known by their eponym as “Jefferson” fractures – have a variable imaging appearance on CT. Traditionally, C1 fractures have been designated as stable or unstable based on the inherent integrity...
Frequency-domain gravitational waves from non-precessing black-hole binaries. II. A phenomenological model for the advanced detector era
Creators: name: Khan, Sebastian
name: Husa, Sascha
name: Hannam, Mark
name: Ohme, Frank
name: Pürrer, Michael
name: Forteza, Xisco Jiménez
name: Bohé, Alejandro
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We present a new frequency-domain phenomenological model of the gravitational-wave signal from the inspiral, merger and ringdown of non-precessing (aligned-spin) black-hole binaries. The model is calibrated to 19 hybrid effective-one-body--numerical-relativity waveforms up to mass ratios of 1:18 and black-hole spins of $|a/m| \sim 0.85$ ($0.98$ for equal-mass systems). The inspiral part of the model consists of an extension of frequency-domain post-Newtonian expressions, using higher-order terms fit to the hybrids. The merger-ringdown is based on a phenomenological ansatz that has been significantly improved over previous models. The model exhibits mismatches of typically less than 1\% against all 19 calibration hybrids, and an additional 29 verification hybrids, which provide strong evidence that, over the calibration region, the model is sufficiently accurate for all relevant gravitational-wave astronomy applications with the Advanced LIGO and Virgo detectors. Beyond the calibration region the model produces physically reasonable results, although we recommend caution in assuming that \emph{any} merger-ringdown waveform model is accurate outside its calibration region. As an example, we note that an alternative non-precessing model, SEOBNRv2 (calibrated up to spins of only 0.5 for unequal-mass systems), exhibits mismatch errors of up to 10\% for high spins outside its calibration region. We conclude that waveform models would benefit most from a larger number of numerical-relativity simulations of high-aligned-spin unequal-mass binaries.
description: 27 pages, 21 figures, Updated coefficients table
title: The external carotid artery and its branches: what we usually skip in our daily studies.
Creators: name: Galante Mulki, Maria
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Anatomy
subject: Arteries / Aorta
subject: Vascular
subject: CT-Angiography
subject: MR-Angiography
subject: Ultrasound
subject: Diagnostic procedure
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: -To review the pathway, anatomical relationships and areas supplied by the external carotid artery and its branches. -To describe the anatomy of the artery and its relationship with other structures in the different techniques, including CTA, MRA,...
Mechanoresponsive diselenide-crosslinked microgels with programmed ultrasound-triggered degradation and radical scavenging ability for protein protection
Creators: name: Kharandiuk, Tetiana
name: Tan, Kok Hui
name: Xu, Wenjing
name: Weitenhagen, Fabian
name: Braun, Susanne
name: Göstl, Robert
name: Pich, Andrij
Publisher: name: Cambridge : RSC Publishing
Year: 2022
Subjects: subject: Controlled release
subject: Controlled-delivery
subject: Crosslinked
subject: Degradation process
subject: Encapsulated proteins
subject: Microgel
subject: Polymer chains
subject: Radical scavenging
subject: Scavenging ability
subject: Watersoluble polymers
subject: 540

description: In the context of controlled delivery and release, proteins constitute a delicate class of cargo requiring advanced delivery platforms and protection. We here show that mechanoresponsive diselenide-crosslinked microgels undergo controlled ultrasound-triggered degradation in aqueous solution for the release of proteins. Simultaneously, the proteins are protected from chemical and conformational damage by the microgels, which disintegrate to water-soluble polymer chains upon sonication. The degradation process is controlled by the amount of diselenide crosslinks, the temperature, and the sonication amplitude. We demonstrate that the ultrasound-mediated cleavage of diselenide bonds in these microgels facilitates the release and activates latent functionality preventing the oxidation and denaturation of the encapsulated proteins (cytochrome C and myoglobin) opening new application possibilities in the targeted delivery of biomacromolecules.
Table evaluating UCT Data from Khaliq et al. 2014 from Comment on an analysis of endotherm thermal tolerances: systematic errors in data compilation undermine its credibility.
Creators: name: Wolf, Blair O.
name: Coe, Brittney H.
name: Gerson, Alexander R.
name: McKechnie, Andrew E.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Physiology
subject: FOS: Biological sciences

description: UCT data used by Khaliq et al. 2014 are evaluated for quality and scored
Groundstates and radial solutions to nonlinear Schrödinger-Poisson-Slater equations at the critical frequency
Creators: name: Mercuri, Carlo
name: Moroz, Vitaly
name: Van Schaftingen, Jean
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35Q55 (Primary), 35J91, 35J47, 35J50, 31B35 (Secondary)

description: We study the nonlocal Schrödinger-Poisson-Slater type equation $$ - Δu + (I_α\ast |u|^p)|u|^{p - 2} u= |u|^{q-2}u\quad\text{in \(\mathbb{R}^N\),} $$ where $N\in\mathbb{N}$, $p>1$, $q>1$ and $I_α$ is the Riesz potential of order $α\in(0,N).$ We introduce and study the Coulomb-Sobolev function space which is natural for the energy functional of the problem and we establish a family of associated optimal interpolation inequalities. We prove existence of optimizers for the inequalities, which implies the existence of solutions to the equation for a certain range of the parameters. We also study regularity and some qualitative properties of solutions. Finally, we derive radial Strauss type estimates and use them to prove the existence of radial solutions to the equation in a range of parameters which is in general wider than the range of existence parameters obtained via interpolation inequalities.
description: 46 pages
High-temperature high-sensitivity AlN-on-SOI Lamb wave resonant strain sensor
Creators: name: Dou, Shaoxu
name: Qi, Mengke
name: Chen, Cong
name: Zhou, Hong
name: Wang, Yong
name: Shang, Zhengguo
name: Yang, Jing
name: Wang, Dengpan
name: Mu, Xiaojing
Publisher: name: New York, NY : American Inst. of Physics
Year: 2018
Subjects: subject: High sensitivity
subject: Lamb wave resonators
subject: Strain behaviors
subject: Strain sensitivity
subject: Temperature characteristic
subject: Temperature compensation
subject: Temperature test
subject: Uniaxial tensile
subject: 530

description: A piezoelectric AlN-on-SOI structured MEMS Lamb wave resonator (LWR) is presented for high-temperature strain measurement. The LWR has a composite membrane of a 1 μm thick AlN film and a 30 μm thick device silicon layer. The excited acoustic waves include Rayleigh wave and Lamb waves. A tensile strain sensor has been prepared with one LWR mounted on a uniaxial tensile plate, and its temperature characteristics from 15.4°C to 250°C and tensile strain behaviors from 0 μϵ to 400 μϵ of Rayleigh wave and S4 mode Lamb wave were tested. The temperature test verifies the adaptability of the tensile strain sensor to temperature up to 250°C, and S4 mode Lamb wave and Rayleigh wave represent almost the same temperature characteristics. The strain test demonstrates that S4 mode Lamb wave shows much higher strain sensitivity (-0.48 ppm/μϵ) than Rayleigh wave (0.05 ppm/μϵ) and confirms its advantage of strain sensitivity. Finally, for this one-LWR strain sensor, a method of beat frequency between S4 mode Lamb wave and Rayleigh wave is proposed for temperature compensation and high-sensitivity strain readout.
title: Clinical utility of S.T.O.N.E, Guy's and Stone Complexity Scoring in predicting the post-operative outcome after single-tract Percutaneous Nephrolithotomy
Creators: name: Khan, Faheemullah
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Kidney
subject: CT
subject: Diagnostic procedure
subject: Outcomes analysis
subject: Surgery
subject: Calcifications / Calculi
subject: Obstruction / Occlusion
subject: Outcomes

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Multiple scoring systems have been formulated to predict the post-operative renal stoneclearance and its complications [1,2,3]. This study is an attempt to; -Assess the clinical utility of S.T.O.N.E, Guy's and Stone Complexity Scoring in achieving...
Who really was Mona Lisa? More than 500 years on, there’s good reason to think we got it wrong
Creators: name: von Guttner Sporzynski, Darius
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 360102
subject: Art history
classificationCode: 430309
subject: Gender history

description: This article explores the enduring mystery surrounding the identity of the Mona Lisa, offering a reevaluation of the traditional belief that the painting depicts Lisa Gherardini, the wife of a Florentine merchant. Instead, a compelling theory suggests that the subject may be Isabella of Aragon, a Renaissance princess with significant political influence. Drawing on scholarly perspectives, stylistic analyses, and historical evidence, the article highlights how Isabella's life aligns with key elements of the portrait. This reinterpretation not only sheds light on the Mona Lisa’s historical context but also repositions Isabella as a significant figure in Renaissance history, deserving of recognition in her own right. The debate underscores the painting’s cultural and historical significance, particularly in relation to the role of women in the Renaissance.
Methods for Recognition of Colorado Beetle (Leptinotarsa decemlineata (Say)) with Multispectral and Color Camera-sensors
Methoden zur Erkennung des Kartoffelkäfers (Leptinotarsa decemlineata (Say)) mit Multispektral- und Farbbildkamera-Sensoren
Creators: name: Dammer, Karl-Heinz
Publisher: name: Berlin ; Heidelberg : Springer
Year: 2022
Subjects: subject: Agro-biocoenosis
subject: Camera sensors
subject: Colorado beetle
subject: Image classification
subject: Leptinotarsa decemlineata
subject: Monitoring
subject: Agrobiozönose
subject: Bildklassifizierung
subject: Kamerasensoren
subject: Kartoffelkäfer
subject: 630
subject: 640
subject: 580
subject: 333.7

description: At the beginning of an epidemic, the Colorado beetle occur sparsely on few potato plants in the field. A target-orientated crop protection applies insecticides only on infested plants. For this, a complete monitoring of the whole field is required, which can be done by camera-sensors attached to tractors or unmanned aerial vehicles (UAVs). The gathered images have to be analyzed using appropriate classification methods preferably in real-time to recognize the different stages of the beetle in high precision. In the paper, the methodology of the application of one multispectral and three commercially available color cameras (RGB) and the results from field tests for recognizing the development stages of the beetle along the vegetation period of the potato crop are presented. Compared to multispectral cameras color cameras are low-cost. The use of artificial neural network for classification of the larvae within the RGB-images are discussed. At the bottom side of the potato leaves the eggs are deposited. Sensor based monitoring from above the crop canopy cannot detect the eggs and the hatching first instar. The ATB developed a camera equipped vertical sensor for scanning the bottom of the leaves. This provide a time advantage for the spray decision of the farmer (e.g. planning of the machine employment, purchase of insecticides). In this paper, example images and a possible future use of the presented monitoring methods above and below the crop surface are presented and discussed.
Table evaluating UCT Data from Khaliq et al. 2014 from Systematic errors in data compilation undermine the credibility of Khaliq et al.'s [1] analysis of endotherm thermal tolerances
Creators: name: Wolf, Blair O.
name: Coe, Brittney H.
name: Gerson, Alexander R.
name: McKechnie, Andrew E.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Physiology
subject: FOS: Biological sciences

description: UCT data used by Khaliq et al. 2014 are evaluated for quality and scored
title: Pulmonary embolism in COVID-19 patients
Creators: name: Waheed, Khawaja Bilal
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Lung
subject: Pulmonary vessels
subject: CT
subject: CT-Angiography
subject: Complications
subject: Screening
subject: Acute
subject: Embolism / Thrombosis

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mainly characterized by fever and respiratory symptoms, with dyspnoea and lung, infiltrates in more severe cases. Many patients also present a pro-coagulant state, which is...
Development, validation, and psychometric analysis of Foot and Ankle Flexibility Index (FAFI)
Creators: name: Martínez-Sebastián, Carlos
name: Gijon-Nogueron, Gabriel
name: Ramos-Petersen, Laura
name: Morales-Asencio, José M
name: Molina-García, Cristina
name: Evans, Angela
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 3202
subject: Clinical sciences
classificationCode: 4201
subject: Allied health and rehabilitation science
classificationCode: 4207
subject: Sports science and exercise

description: Aim: To develop a new tool for identifying joint hypermobility of the paediatric foot and ankle, based on a dichotomous scoring system utilising the Lower Limb Assessment Score (LLAS), to separate the foot and ankle items. Material and methods: A total of 205 children, aged between 5 and 10 years, participated in a cross-sectional study. The new tool Foot and Ankle Flexibility Index (FAFI) was predicated upon the last 7 items of LLAS, which are specific to the foot and ankle. The internal consistency was measured with Cronbach's test. Kappa statistics with 95% CI were calculated to verify the level of inter-rater and intra-rater agreement for the FAFI. Results: Cronbach's alpha returned 0.82. The correlations between items returned a mean of 0.59 (range: 0.43–0.74). The discrimination score on the ROC curve (4 points) showed that the model can be used to identify children with joint hypermobility of the foot and ankle. Inter-rater reliability was largely good (ICC = 0.89). Excellent intra-rater reliability was found (ICC = 0.96) Conclusions: This study identified high reliability between evaluators, and high sensitivity and specificity, for a new reliable and valid tool for the identification of foot and ankle joint hypermobility.
Genetic algorithm implementation for effective document subject search
Creators: name: Ivanov, V. K.
name: Meskin, P. I.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Retrieval (cs.IR)
subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: This paper describes the software implementation of genetic algorithm for identifying and selecting most relevant results received during sequentially executed subject search operations. Simulated evolutionary process generates sustainable and effective population of search queries, forms search pattern of documents or semantic core, creates relevant sets of required documents, allows automatic classification of search results. The paper discusses the features of subject search, justifies the use of a genetic algorithm, describes arguments of the fitness function and describes basic steps and parameters of the algorithm.
description: in Russian
title: Reproducibility of coronary calcium score using deep learning image reconstruction algorithm for CT: a phantom study
Creators: name: Inokuchi, Yasuhiro
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Cardiac
subject: CT
subject: Computer Applications-Detection, diagnosis
subject: Calcifications / Calculi

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: The aim of this study was to investigated reproducibility of deep learning image reconstruction (DLIR) algorithm to coronary calcium...
MPEC 2023-T231 : 2023 TY9
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 TY9

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
A Correlation Analysis Method for Power Systems Based on Random Matrix Theory
Creators: name: Xu, Xinyi
name: He, Xing
name: Ai, Qian
name: Qiu, Robert C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: The operating status of power systems is influenced by growing varieties of factors, resulting from the developing sizes and complexity of power systems; in this situation, the modelbased methods need be revisited. A data-driven method, as the novel alternative, on the other hand, is proposed in this paper: it reveals the correlations between the factors and the system status through statistical properties of data. An augmented matrix, as the data source, is the key trick for this method; it is formulated by two parts: 1) status data as the basic part, and 2) factor data as the augmented part. The random matrix theory (RMT) is applied as the mathematical framework. The linear eigenvalue statistics (LESs), such as the mean spectral radius (MSR), are defined to study data correlations through large random matrices. Compared with model-based methods, the proposed method is inspired by a pure statistical approach, without a prior knowledge of operation and interaction mechanism models for power systems and factors. In general, this method is direct in analysis, robust against bad data, universal to various factors, and applicable for real-time analysis. A case study, based on the standard IEEE 118-bus system, validates the proposed method.
description: 9 pages, 9 figures, Accepted by IEEE Trans on Smart Grid
Spectral Theory of Infinite Quantum Graphs
Creators: name: Exner, Pavel
name: Kostenko, Aleksey
name: Malamud, Mark
name: Neidhardt, Hagen
Publisher: name: Cham (ZG) : Springer International Publishing AG
Year: 2018
Subjects: subject: self-adjoint extensions
subject: dimensional schrodinger operator
subject: boundary-value-problems
subject: dirichlet forms
subject: laplacian
subject: approximation
subject: convergence
subject: couplings
subject: networks
subject: matrices
subject: 530
subject: 510

description: We investigate quantum graphs with infinitely many vertices and edges without the common restriction on the geometry of the underlying metric graph that there is a positive lower bound on the lengths of its edges. Our central result is a close connection between spectral properties of a quantum graph and the corresponding properties of a certain weighted discrete Laplacian on the underlying discrete graph. Using this connection together with spectral theory of (unbounded) discrete Laplacians on infinite graphs, we prove a number of new results on spectral properties of quantum graphs. Namely, we prove several self-adjointness results including a Gaffney-type theorem. We investigate the problem of lower semiboundedness, prove several spectral estimates (bounds for the bottom of spectra and essential spectra of quantum graphs, CLR-type estimates) and study spectral types.
Methylated genes in breast cancer: Associations with clinical and histopathological features in a familial breast cancer cohort
Creators: name: Swift-Scanlan, Theresa
name: Sukumar, Saraswati
name: Fackler, Mary Jo
name: Vang, Russell
name: Blackford, Amanda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Hundreds of hypermethylated genes have been described in breast cancer, yet the nature and contribution of these genes in their methylated state to overall risk and prognosis is under-characterized in non-sporadic breast cancers. We therefore compared associations of DNA methylation with tumor stage, hormone/growth receptor status and clinical outcomes in a familial breast cancer cohort. Because few previous methylation studies have considered the oncogenic or tumor suppressor properties of their gene sets, this functional status was included as part of our correlative analysis.
title: Hepatic metastases and diffuse steatosis – hiding in plain sight
Creators: name: Fonseca Torres, Tiago
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: Liver
subject: Oncology
subject: CT
subject: Ultrasound
subject: Education
subject: Metastases

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To revisit the imaging features of diffuse hepatic steatosis and reinforce its impact in the concealment of hepatic metastatic...
Dietary calcium supplementation enhances efficacy but also toxicity of EGFR inhibitor therapy for colon cancer
Creators: name: Threadgill, David W.
name: Rinella, Erica S.
name: Bankaitis, Eric D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The inverse correlation between levels of dietary calcium and colorectal cancer (CRC) incidence has been extensively investigated. However, the impact of supplemental calcium on cancer therapy remains unknown. We used four models of CRC, Caco-2 and HCT116 human cancer cell lines and ApcMin/+ and azoxymethane carcinogen-induced mouse models, to investigate the impact of a Western-style diet low in calcium (0.05%) vs. a similar diet but supplemented with calcium (5%) on therapeutic targeting of the epidermal growth factor receptor (EGFR). We found that calcium supplementation combined with pharmacologic blockade of EGFR results in an additive effect on tumor growth inhibition in all models. Unexpectedly, the combined use of dietary calcium supplementation and EGFR inhibitors also resulted in elevated toxicity suggesting that careful consideration be given when combining dietary supplements with prescribed cancer therapies.
Electronic supplementary material from Maintaining mimicry diversity: optimal warning colour patterns differ among microhabitats in Amazonian clearwing butterflies.
Creators: name: Willmott, Keith R.
name: Willmott, Julia C. Robinson
name: Elias, Marianne
name: Jiggins, Chris D.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Map of study location, butterfly and bird distribution data, results from analyses and further information about methods.
Supplement for 'Multi-molecular 14C evidence for mineral control on terrestrial carbon storage and export'
Creators: name: Gies, Hannah
name: Lupker, Maarten
name: Galy, Valier
name: Hemingway, Jordon
name: Boehman, Brenna
name: Schwab, Melissa
name: Haghipour, Negar
name: Eglinton, Timothy
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Geochemistry
subject: FOS: Earth and related environmental sciences

description: contains a complementary figure and data tables
Inhibition of oncogenic Pim-3 kinase modulates transformed growth and chemosensitizes pancreatic cancer cells to gemcitabine
Creators: name: Xu, Dapeng
name: White, Catherine D.
name: Bednarski, Brian K.
name: Witherspoon, Sam M.
name: Kim, Hong Jin
name: Baldwin, Albert S.
name: Taverna, Pietro
name: Gavilano, Lily
name: Williams, Daniel
name: Baines, Antonio T.
name: Cobb, Michael G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with a 5-year survival rate of only 6%. Although the cytosine analog gemcitabine is the drug commonly used to treat PDAC, chemoresistance unfortunately renders the drug ineffective. Thus, strategies that can decrease this resistance will be essential for improving the dismal outcome of patients suffering from this disease. We previously observed that oncogenic Pim-1 kinase was aberrantly expressed in PDAC tissues and cell lines and was responsible for radioresistance. Furthermore, members of the Pim family have been shown to reduce the efficacy of chemotherapeutic drugs in cancer. Therefore, we attempted to evaluate the role of Pim-3 in chemoresistance of PDAC cells. We were able to confirm upregulation of the Pim-3 oncogene in PDAC tissues and cell lines vs. normal samples. Biological consequences of inhibiting Pim-3 expression with shRNA-mediated suppression included decreases in anchorage-dependent growth, invasion through Matrigel and chemoresistance to gemcitabine as measured by caspase-3 activity. Additionally, we were able to demonstrate that Pim-1 and Pim-3 play overlapping but non-identical roles as it relates to gemcitabine sensitivity of pancreatic cancer cells. To further support the role of Pim-3 suppression in sensitizing PDAC cells to gemcitabine, we used the pharmacological Pim kinase inhibitor SGI-1776. Treatment of PDAC cells with SGI-1776 resulted in decreased phosphorylation of the proapoptotic protein Bad and cell cycle changes. When SGI-1776 was combined with gemcitabine, there was a greater decrease in cell viability in the PDAC cells vs. cells treated with either of the drugs separately. These results suggest combining drug therapies that inhibit Pim kinases, such as Pim-3, with chemotherapeutic agents, to aid in decreasing chemoresistance in pancreatic cancer.
title: ECR 2022: Building bridges between coronary artery geometry and atherosclerosis - an educational poster enlightening pathophysiology and potentialities in the era of state-of-the-art coronary CTA
Creators: name: Rafailidis, Vasileios
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Cardiac
subject: CT-Angiography
subject: Diagnostic procedure
subject: Arteriosclerosis

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To highlight associations between geometric features of coronary arteries and the extent of atherosclerosis, presenting data from interventional coronary angiography (ICA) and coronary computed tomographic angiography (CCTA) studies. To define...
The Veracity Problem: Detecting False Information and its Propagation on Online Social Media Networks
Creators: name: Condran, Sarah
Publisher: name: arXiv
Year: 2024
Subjects: subject: Social and Information Networks (cs.SI)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: 68T99

description: Detecting false information on social media is critical in mitigating its negative societal impacts. To reduce the propagation of false information, automated detection provide scalable, unbiased, and cost-effective methods. However, there are three potential research areas identified which once solved improve detection. First, current AI-based solutions often provide a uni-dimensional analysis on a complex, multi-dimensional issue, with solutions differing based on the features used. Furthermore, these methods do not account for the temporal and dynamic changes observed within the document's life cycle. Second, there has been little research on the detection of coordinated information campaigns and in understanding the intent of the actors and the campaign. Thirdly, there is a lack of consideration of cross-platform analysis, with existing datasets focusing on a single platform, such as X, and detection models designed for specific platform.
 This work aims to develop methods for effective detection of false information and its propagation. To this end, firstly we aim to propose the creation of an ensemble multi-faceted framework that leverages multiple aspects of false information. Secondly, we propose a method to identify actors and their intent when working in coordination to manipulate a narrative. Thirdly, we aim to analyse the impact of cross-platform interactions on the propagation of false information via the creation of a new dataset.
description: 4 pages, 3 figures
Enhanced Magnetic Trap Loading for Atomic Strontium
Creators: name: Barker, D. S.
name: Reschovsky, B. J.
name: Pisenti, N. C.
name: Campbell, G. K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We report on a technique to improve the continuous loading of atomic strontium into a magnetic trap from a Magneto-Optical Trap (MOT). This is achieved by adding a depumping laser tuned to the 3P1 to 3S1 (688-nm) transition. The depumping laser increases atom number in the magnetic trap and subsequent cooling stages by up to 65 % for the bosonic isotopes and up to 30 % for the fermionic isotope of strontium. We optimize this trap loading strategy with respect to the 688-nm laser detuning, intensity, and beam size. To understand the results, we develop a one-dimensional rate equation model of the system, which is in good agreement with the data. We discuss the use of other transitions in strontium for accelerated trap loading and the application of the technique to other alkaline-earth-like atoms.
description: 8 pages, 8 figures
Analysis of the expression of human tumor antigens in ovarian cancer tissues
Creators: name: Ali-Fehmi, Rouba
name: Tainsky, Michael A.
name: Arabi, Haitham
name: Alekseev, Oleg M.
name: Bandyopadhyay, Sudeshna
name: Abrams, Judith
name: Chatterjee, Madhumita
name: Ionan, Alexei
name: Bryant, Christopher S.
name: Shah, Jay P.
name: Levin, Nancy K.
name: Hewitt, Stephen M.
name: O'Rand, Michael G.
name: Munkarah, Adnan
name: Morris, Robert
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Biomarkers for early detection of cancer have great clinical diagnostic potential. Numerous reports have documented the generation of humoral immune responses that are triggered in response to changes in protein expression patterns in tumor tissues and these biomarkers are referred to as tumor associated antigens (TAAs). Using a high-throughput technology, we previously identified 65 proteins as diagnostically useful TAAs by profiling the humoral immune responses in ovarian cancer (OVCA) patients. Here we determined the expression status of some of those TAAs in tissues from OVCA patients. The protein expression patterns of 4 of those 65 antigens, namely NASP, RCAS1, Nijmegen breakage syndrome1 (NBS1) and eIF5A, along with p53 and Her2 (known molecular prognosticators) and two proteins that interact with NBS1, MRE11 and RAD50, were assessed by immunohistochemistry (IHC). NASP and RCAS1 proteins were more frequently expressed in ovarian cancer tissues than with normal ovarian tissue and serous cystadenomas and MRE11 was less frequently expressed. When evaluated simultaneously, only NASP and MRE11 remained statistically significant with sensitivity of 66% and specificity of 89%. None of these proteins’ expression levels were prognostic for survival. Together, our results indicate that occurrence of humoral immune responses against some of these TAAs in OVCA patients is triggered by antigen protein overexpression.
Somatic gene mutations in African Americans may predict worse outcomes in colorectal cancer
Creators: name: Keku, Temitope O.
name: Kim, Sangmi
name: Martin, Chris F.
name: Araujo-Perez, Felix
name: Galanko, Joseph A.
name: Shen, Xiang J.
name: Sandler, Robert S.
name: Kang, Melissa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: African Americans have worse outcomes in colorectal cancer (CRC) than Caucasians. We sought to determine if KRAS, BRAF and PIK3CA mutations might contribute to the racial differences in CRC outcome.
Estimation of integrated quadratic covariation with endogenous sampling times
Creators: name: Potiron, Yoann
name: Mykland, Per
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Finance (q-fin.ST)
subject: FOS: Economics and business

description: When estimating high-frequency covariance (quadratic covariation) of two arbitrary assets observed asynchronously, simple assumptions, such as independence, are usually imposed on the relationship between the prices process and the observation times. In this paper, we introduce a general endogenous two-dimensional nonparametric model. Because an observation is generated whenever an auxiliary process called observation time process hits one of the two boundary processes, it is called the hitting boundary process with time process (HBT) model. We establish a central limit theorem for the Hayashi-Yoshida (HY) estimator under HBT in the case where the price process and the observation price process follow a continuous Ito process. We obtain an asymptotic bias. We provide an estimator of the latter as well as a bias-corrected HY estimator of the high-frequency covariance. In addition, we give a consistent estimator of the associated standard error.