cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Emergence of active nematics in bacterial biofilms
Creators: name: Yaman, Yusuf Ilker
name: Demir, Esin
name: Vetter, Roman
name: Kocabas, Askin
Publisher: name: arXiv
Year: 2018
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Growing tissue and bacterial colonies are active matter systems where cell divisions and cellular motion generate active stress. Although they operate in the non-equilibrium regime, these biological systems can form large-scale ordered structures such as nematically aligned cells, topological defects, and fingerings. Mechanical instabilities also play an essential role during growth by generating large structural folding. How active matter dynamics and mechanical instabilities together develop large-scale order in growing tissue is not well understood. Here, we use chain forming Bacillus subtilis, also known as a biofilm, to study the direct relation between active stress and nematic ordering. We find that a bacterial biofilm has intrinsic length scales above which series of mechanical instabilities occur. Localized stress and friction control both linear buckling and edge instabilities. Remarkably, these instabilities develop nematically aligned cellular structures and create pairs of motile and stationary topological defects. We also observe that stress distribution across the biofilm strongly depends on the defect dynamics which can further initiate the formation of sporulation sites by creating three-dimensional structures. By investigating the development of bacterial biofilms and their mechanical instabilities we are proposing a new type of active matter system which provides a unique platform to study the essential roles of nematics in growing biological tissue.
Tenascin C interacts with Ecto-5′-nucleotidase (eN) and regulates adenosine generation in cancer cells
Creators: name: Sadej, Rafal
name: Inai, Kunihiro
name: Mitchell, Beverly S.
name: Spychala, Jozef
name: Ostapkowicz, Anna
name: Skladanowski, Andrzej C.
name: Kohler, Jon
name: Rajfur, Zenon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Tenascin C is expressed in invasive human solid tumors; however its specific role in cancer biology remains obscure. Previously, we have found that ecto-5'-nucleotidase (eN) is a marker of ER (-) breast carcinoma and elevated expression correlates with invasive mesenchymal cell phenotype. To investigate for the potential relationship between eN and protein components of the extracellular matrix (ECM) we measured adenosine generation from AMP in cells incubated with soluble ECM proteins. We found that tenascin C was the only ECM component that strongly inhibited ecto-5'-nucleotidase (eN) activity in situ and adenosine generation from AMP (75% inhibition, p < 0.01). The inhibition was comparable to that induced by concanavalin A, a well-defined and strong inhibitor of eN. Resin immobilized tenascin C, but not collagen, and only weakly fibronectin, specifically and quantitatively bound cell-extracted eN. We further developed breast cancer cell line with reduced eN expression and tested changes in cell adhesion on different ECM. Breast cancer cells expressing reduced eN attached 56% weaker (p < 0.05) to immobilized tenascin C. This difference was not detected with other ECM proteins. Finally, control breast cancer cells migrated slower on tenascin C when compared with clone with reduced eN expression. These data suggest that eN is a novel and specific receptor for tenascin C and that the interaction between these proteins may influence cell adhesion and migration and also lead to decreased generation of local adenosine.
The ubiquitin–proteasome system in cardiac dysfunction
Creators: name: Mearini, Giulia
name: Carrier, Lucie
name: Schlossarek, Saskia
name: Willis, Monte S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Abstract Since proteins play crucial roles in all biological processes, the finely tuned equilibrium between their synthesis and degradation regulates cellular homeostasis. Controlling the quality of proteome informational content is essential for cell survival and function. After initial synthesis, membrane and secretory proteins are modified, folded, and assembled in the endoplasmic reticulum, whereas other proteins are synthesized and processed in the cytosol. Cells have different protein quality control systems, the molecular chaperones, which help protein folding and stabilization, and the ubiquitin–proteasome system (UPS) and lysosomes, which degrade proteins. It has generally been assumed that UPS and lysosomes are regulated independently and serve distinct functions. The UPS degrades both cytosolic, nuclear proteins, and myofibrillar proteins, whereas the lysosomes degrade most membrane and extracellular proteins by endocytosis as well as cytosolic proteins and organelles via autophagy. Over the last two decades, the UPS has been increasingly recognized as a major system in several biological processes including cell proliferation, adaptation to stress and cell death. More recently, activation or impairment of the UPS has been reported in cardiac disease and recent evidence indicate that autophagy is a key mechanism to maintain cardiac structure and function. This review mainly focuses on the UPS and its various components in healthy and diseased heart, but also summarizes recent data suggesting parallel activation of the UPS and autophagy in cardiac disease.
Additional file 3: of Development and validation of a simple screening tool for caregiver grief in dementia caregiving
Creators: name: Tau Ming Liew
name: Tai, Bee Choo
name: Yap, Philip
name: Koh, Gerald Choon-Huat
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Marine Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Demographic characteristics of the caregivers and persons with dementia in the separate validation sample (nâ =â 103) (DOCX 35 kb)
Evaluating remote sensing of deciduous forest phenology at multiple spatial scales using PhenoCam imagery
Creators: name: Klosterman, S. T.
name: Richardson, A. D.
name: Sonnentag, O.
name: Norman, R.
name: Friedl, M. A.
name: Mitchell, L.
name: Melaas, E.
name: Hufkens, K.
name: Lavine, I.
name: Gray, J. M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Plant phenology regulates ecosystem services at local and global scales and is a sensitive indicator of global change. Estimates of phenophase transition dates, such as the start of spring or end of fall, can be derived from sensor-based time series, but must be interpreted in terms of biologically relevant events. We use the PhenoCam archive of digital repeat photography to implement a consistent protocol for visual assessment of canopy phenology at 13 temperate deciduous forest sites throughout eastern North America, and to perform digital image analysis for time-series-based estimation of phenophase transition dates. We then compare these results to remote sensing metrics of phenophase transition dates derived from the Moderate Resolution Imaging Spectroradiometer (MODIS) and Advanced Very High Resolution Radiometer (AVHRR) sensors. We present a new type of curve fit that uses a generalized sigmoid function to estimate phenology dates, and we quantify the statistical uncertainty of phenophase transition dates estimated using this method. Results show that the generalized sigmoid provides estimates of dates with less statistical uncertainty than other curve-fitting methods. Additionally, we find that dates derived from analysis of high-frequency PhenoCam imagery have smaller uncertainties than satellite remote sensing metrics of phenology, and that dates derived from the remotely sensed enhanced vegetation index (EVI) have smaller uncertainty than those derived from the normalized difference vegetation index (NDVI). Near-surface time-series estimates for the start of spring are found to closely match estimates derived from visual assessment of leaf-out, as well as satellite remote-sensing-derived estimates of the start of spring. However late spring and fall phenology metrics exhibit larger differences between near-surface and remote scales. Differences in late spring phenology between near-surface and remote scales are found to correlate with a landscape metric of deciduous forest cover. These results quantify the effect of landscape heterogeneity when aggregating to the coarser spatial scales of remote sensing, and demonstrate the importance of accurate curve fitting and vegetation index selection when analyzing and interpreting phenology time series.
The Distance and Motion of the Maffei Group
Creators: name: Anand, Gagandeep S.
name: Tully, R. Brent
name: Rizzi, Luca
name: Karachentsev, Igor D.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: It has recently been suggested that the nearby galaxies Maffei 1 and 2 are further in distance than previously thought, such that they no longer are members of the same galaxy group as IC 342. We reanalyze near-infrared photometry from the Hubble Space Telescope, and find a distance to Maffei 2 of $5.73\pm0.40$ Mpc. With this distance, the Maffei Group lies 2.5 Mpc behind the IC 342 Group and has a peculiar velocity toward the Local Group of $-128\pm33$ km/s. The negative peculiar velocities of both of these distinct galaxy groups are likely the manifestation of void expansion from the direction of Perseus-Pisces.
description: 6 pages, 2 figures, Accepted to ApJL (replacement adjusts/fixes luminosities in table 1)
Quantum computation using electrons trapped by surface acoustic waves
Creators: name: Barnes, C. H. W.
name: Shilton, J. M.
name: Robinson, A. M.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We describe in detail a set of ideas for implementing qubits, quantum gates and quantum gate networks in a semiconductor heterostructure device. Our proposal is based on an extension of the technology used for surface acoustic wave (SAW) based single-electron transport devices. These devices allow single electrons to be captured from a two-dimensional electron gas in the potential minima of a SAW. We discuss how this technology can be adapted to allow the capture of electrons in pure spin states and how both single and two-qubit gates can be constructed using magnetic and non-magnetic gate technology. We give designs for readout gates to allow the spin state of the electrons to be measured and discuss how combinations of gates can be connected to make multi-qubit networks. Finally we consider decoherence and other sources of error, and how they can be minimized for our design.
Additional file 1: of Are big data analytics helpful in caring for multimorbid patients in general practice? - A scoping review
Creators: name: Waschkau, Alexander
name: Wilfling, Denise
name: SteinhĂ¤User, Jost
Publisher: name: figshare
Year: 2019
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Search Strategy.pdf. Detailed Information on search strategy. Information on search strategy, search results, and exclusion criterias. (PDF 47 kb)
Electronic transport in disordered interacting systems
Creators: name: Vojta, Thomas
name: Epperlein, Frank
Publisher: name: arXiv
Year: 1998
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We numerically investigate the transport properties of disordered interacting electrons in three dimensions in the metallic as well as in the insulating phases. The disordered many-particle problem is modeled by the quantum Coulomb glass which contains a random potential, long-range unscreened Coulomb interactions and quantum hopping between different sites. We have recently developed the Hartree-Fock based diagonalization (HFD) method which amounts to diagonalizing the Hamiltonian in a suitably chosen energetically truncated basis. This method allows us to investigate comparatively large systems. Here we calculate the combined effect of disorder and interactions on the dissipative conductance. We find that the qualitative influence of the interactions on the conductance depends on the relative disorder strength. For strong disorder interactions can significantly enhance the transport while they suppress the conductance for weak disorder.
description: 5 pages, 2 EPS figures included, presented at the 210. WE-Heraeus Seminar on Percolation, interaction and localization: simulations of transport in disordered systems
Technical Note: Time lag correction of aquatic eddy covariance data measured in the presence of waves
Creators: name: Reidenbach, M. A.
name: Huettel, M.
name: Özkan-Haller, H. T.
name: Delgard, M. L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Extracting benthic oxygen fluxes from eddy covariance time series measured in the presence of surface gravity waves requires careful consideration of the temporal alignment of the vertical velocity and the oxygen concentration. Using a model based on linear wave theory and measured eddy covariance data, we show that a substantial error in flux can arise if these two variables are not aligned correctly in time. We refer to this error in flux as the time lag bias. In one example, produced with the wave model, we found that an offset of 0.25 s between the oxygen and the velocity data produced a 2-fold overestimation of the flux. In another example, relying on nighttime data measured over a seagrass meadow, a similar offset reversed the flux from an uptake of −50 mmol m−2 d−1 to a release of 40 mmol m−2 d−1. The bias is most acute for data measured at shallow-water sites with short-period waves and low current velocities. At moderate or higher current velocities (> 5–10 cm s-1), the bias is usually insignificant. The widely used traditional time shift correction for data measured in unidirectional flows, where the maximum numerical flux is sought, should not be applied in the presence of waves because it tends to maximize the time lag bias or give unrealistic flux estimates. Based on wave model predictions and measured data, we propose a new time lag correction that minimizes the time lag bias. The correction requires that the time series of both vertical velocity and oxygen concentration contain a clear periodic wave signal. Because wave motions are often evident in eddy covariance data measured at shallow-water sites, we encourage more work on identifying new time lag corrections.
The spin gap of CaV4O9 revisited
Creators: name: Mambrini, M.
name: Mila, F.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The large-plaquette scenario of the spin gap in CaV4O9 is investigated on the basis of extensive exact diagonalizations. We confirm the existence of a large-plaquette phase in a wide range of parameters, and we show that the most recent neutron scattering data actually require an intra-plaquette second neighbor exchange integral much larger than the inter-plaquette one, thus justifying the perturbative calculation used in the interpretation of the neutron scattering experiments.
description: 2 pages with 3 figures
Additional file 1: of Factors predicting home medication management practices among chronically ill older population of selected districts of Nepal
Creators: name: Shrestha, Shakti
name: Poudel, Ramesh
name: Pradhan, Saroj
name: Aashutosh Adhikari
name: Giri, Arjun
name: Poudel, Arjun
Publisher: name: figshare
Year: 2019
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Data collection tool. A sheet designed to collect information on four different aspects of participants including socio-demographic characteristics, illness characteristics, life styles and medication management practice. (PDF 301 kb)
A framework for device-to-device communication between mobile devices using heterogeneous channels
Creators: name: Kalbarczyk, Tomasz Stanislaw
name: 0000-0003-3839-4626
Publisher: name: The University of Texas at Austin
Year: 2019
Subjects: Computer science
Embedded systems
Smart environments
Middleware
Access control
Internet of Things
Device to device communication

description: Device-to-device (D2D) communication technologies are growing in availability and popularity and are commonly used to facilitate applications in the Internet of Things (IoT) environments. Such environments are characterized by heterogeneous devices, often employing diverse communication technologies with varying energy consumption, discovery ranges, and transmission rates. These complexities pose a daunting setting for the development of IoT applications that could leverage the direct communication with the proximal mobile and embedded devices in this burgeoning landscape. While current approaches focus either on device discovery in the IoT setting or content transfer once communication channels are established, none facilitate the intelligent discovery of useful devices and the seamless formation of temporary D2D connections to transfer content between said devices. Our Omni middleware provides both of these features critical in the development of applications which desire to leverage proximal devices in the IoT setting. Using Omni, we demonstrate the feasibility of building applications that leverage heterogeneous D2D communication channels in an efficient and realistic (in terms of energy and time) manner. To address the issue of learning access control policies integral to the usability of Omni in realistic IoT applications, we develop the LAD framework for learning and enforcing data access control policies using context-based attributes derived via D2D links to proximal mobile and embedded devices. Existing approaches use tag-based attributes for such access control policies, which do not afford the same granularity or reusability as seamlessly generated and dynamic context-based attributes. The seamless generation of context-based attributes means that LAD is able to provide finer granularity of attributes without incurring the additional overhead associated with users manually adding tags or training a classifier for tagging. The dynamic nature of the attributes makes them reusable since they evolve with a changing environment. We deploy an extensive, sensor testbed across multiple floors of an industrial-sized academic building walked by several mobile participants to generate a rich, real-life dataset on which to evaluate the performance of our LAD framework in a variety of access control and anomaly detection use cases.
New Constraints on Xenonphobic Dark Matter from DEAP-3600
Creators: name: Yaguna, Carlos E.
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The first-year results from DEAP-3600, a single-phase liquid argon direct-detection dark matter experiment, were recently reported. At first sight, they seem to provide no new constraints, as the limit lies well within the region already excluded by three different xenon experiments: LUX, PandaX-II, and XENON1T. We point out, however, that this conclusion is not necessarily true, for it is based on the untested assumption that the dark matter particle couples equally to protons and neutrons. For the more general case of isosping-violating dark matter, we find that there are regions in the parameter space where DEAP-3600 actually provides the most stringent limits on the dark matter-proton spin-independent cross section. Such regions correspond to the so-called Xenonphobic dark matter scenario, for which the neutron-to-proton coupling ratio is close to $-0.7$. Our results seem to signal the beginning of a new era in which the complementarity among different direct detection targets will play a crucial role in the determination of the fundamental properties of the dark matter particle.
description: 10 pages. V2: matches published version
Disengagement of Visual Attention in Infancy is Associated with Emerging Autism in Toddlerhood
Creators: name: Charman, Tony
name: Johnson, Mark H.
name: Fernandes, Janice
name: Dawson, Geraldine
name: Jane Webb, Sara
name: Elsabbagh, Mayada
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: BackgroundEarly emerging characteristics of visual orienting have been associated with a wide range of typical and atypical developmental outcomes. In the current study, we examined the development of visual disengagement in infants at risk for autism.MethodsWe measured the efficiency of disengaging from a central visual stimulus to orient to a peripheral one in a cohort of 104 infants with and without familial risk for autism by virtue of having an older sibling with autism.ResultsAt 7 months of age, disengagement was not robustly associated with later diagnostic outcomes. However, by 14 months, longer latencies to disengage in the subset of the risk group later diagnosed with autism was observed relative to other infants at risk and the low-risk control group. Moreover, between 7 months and 14 months, infants who were later diagnosed with autism at 36 months showed no consistent increases in the speed and flexibility of visual orienting. However, the latter developmental effect also characterized those infants who exhibited some form of developmental concerns (but not meeting criteria for autism) at 36 months.ConclusionsInfants who develop autism or other developmental concerns show atypicality in the development of visual attention skills from the first year of life.
Nanometer Scale Mapping of the Density of States in an Inhomogeneous Superconductor
Creators: name: Cren, T.
name: Roditchev, D.
name: Sacks, W.
name: Klein, J.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Using high speed scanning tunneling spectroscopy, we perform a full mapping of the quasiparticle density of states (DOS) in single crystals of BiPbSrCaCuO(2212). The measurements carried out at 5 K showed a complex spatial pattern of important variations of the local DOS on the nanometer scale. Superconducting areas are co-existing with regions of a smooth and larger gap-like DOS structure. The superconducting regions are found to have a minimum size of about 3 nm. The role of Pb-introduced substitutional disorder in the observed spatial variations of the local DOS is discussed.
description: 4 page Letter with 3 figures (2 color figures)
Comparison of granulocyte colony-stimulating factor (G-CSF)--mobilized peripheral blood progenitor cells and G-CSF--stimulated bone marrow as a source of stem cells in HLA-matched sibling transplantation
Creators: name: Sparks, Scotty D.
name: Serody, Jonathan S.
name: Schell, Michael J.
name: Gabriel, Don A.
name: Wiley, Joseph M.
name: Brecher, Mark E.
name: Folds, James
name: Bigelow, Sharon H.
name: Capel, Eileen J.
name: Kirby, Suzanne L.
name: Lin, Yuhua
name: Shea, Thomas C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: AbstractHLA-identical bone marrow or stem cell transplantation from a sibling is the preferred treatment for patients with chronic myelogenous leukemia, bone marrow failure syndromes, relapsed acute leukemia, and specific inborn errors of metabolism. Several groups have shown that granulocyte colony-stimulating factor (G-CSF)--mobilized peripheral blood progenitor cells (PBPCs) obtained from HLA-matched siblings are effective in reconstitution of marrow function after marrow ablative conditioning therapy. To evaluate whether G-CSF treatment before bone marrow harvest leads to enhanced recovery of PBPC counts and recovery from limited graft-versus-host disease (GVHD), we assessed the outcome of a sequential cohort of patients treated identically and then given either G-CSF--mobilized PBPCs or G-CSF--stimulated bone marrow from HLA-identical siblings. We show that the time to neutrophil engraftment is identical in the 2 cohorts, whereas platelet engraftment is earlier with the use of PBPCs. The incidence of acute GVHD was decreased, and that of chronic GVHD significantly decreased, in the group receiving bone marrow. Overall survival was not different between the 2 groups. Thus, G-CSF--stimulated bone marrow offers a source of stem cells that allows for early neutrophil engraftment with a decreased risk of GVHD.Biol Blood Marrow Transplant 2000;6(4A):434-40.
Residual entropy and spin gap in a one-dimensional analog of the pyrochlore antiferromagnet
Creators: name: Mambrini, M.
name: Trebosc, J.
name: Mila, F.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We show that the low-energy sector of the S=1/2, antiferromagnetic Heisenberg model on a one-dimensional lattice of coupled tetrahedra consists of 2^N replica of the spectrum of the dimerized Heisenberg chain, where N is the number of tetrahedra. This provides a proof of the following properties: i) there is a residual ground-state entropy per spin equal to 2^{1/4}; ii) there is a singlet-triplet gap as long as the coupling between the tetrahedra is smaller than the internal one. These properties are compared to available results on the pyrochlore lattice.
description: 4 pages with 3 figures
An expanded phase I/II trial of cyclophosphamide, etoposide, and carboplatin plus total body irradiation with autologous marrow or stem cell support for patients with hematologic malignancies
Creators: name: Moore, Dominic T.
name: Capel, Eileen
name: Sailer, Scott
name: Dent, Georgette
name: Shea, Thomas C.
name: Bruner, Rebecca
name: Bentley, Stuart
name: Brecher, Mark E.
name: Serody, Jonathan S.
name: Gabriel, Don A.
name: Wiley, Joseph M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: AbstractThe major cause for failure of autologous stem cell transplantation for hematologic malignancies is the risk of recurrent disease. As a result, new treatment regimens that include novel agents or combinations of agents and approaches are needed. The current report describes a large Phase I/II, single-center trial that includes 60 patients with a variety of hematologic malignancies. These patients received a fixed dose of carboplatin (1 g/m2/d × 72 hours by CI) etoposide (600 mg/m2/d × 3 days) and cyclophosphamide (2 g/m2/d × 3 days), plus escalating doses of total body irradiation (TBI) (at 1000, 1200, and 1295 cGy) over 3 days. Eleven patients received infusion of autologous marrow, 32 received peripheral blood stem cells, and 17 patients received both. The maximum tolerated dose of this regimen was a radiation dose of 1200 cGy given in 200-cGy fractions BID × 3 days. The dose-limiting toxicity was mucositis, with 97% of patients requiring narcotic analgesia for mouth pain. Overall treatment-related mortality was 6.7%, with 2 of the 4 deaths occurring in a group of 9 patients aged 60 and older. Responses were seen in all patient groups, but the most encouraging outcomes were seen in 12 patients with high-risk or advanced acute myelocytic lymphoma (AML), 7 of whom remain alive and free of disease beyond 5 years. This regimen is intensive and causes considerable mucositis but is otherwise well tolerated and has demonstrated activity in a number of hematologic malignancies, especially AML.
Anomalous dephasing of bosonic excitons interacting with phonons in the vicinity of the Bose-Einstein condensation
Creators: name: Schmitt, O. M.
name: Thoai, D. B. Tran
name: Gartner, P.
name: Haug, H.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The dephasing and relaxation kinetics of bosonic excitons interacting with a thermal bath of acoustic phonons is studied after coherent pulse excitation. The kinetics of the induced excitonic polarization is calculated within Markovian equations both for subcritical and supercritical excitation with respect to a Bose-Einstein condensation (BEC). For excited densities n below the critical density n_c, an exponential polarization decay is obtained, which is characterized by a dephasing rate G=1/T_2. This dephasing rate due to phonon scattering shows a pronounced exciton-density dependence in the vicinity of the phase transition. It is well described by the power law G (n-n_c)^2 that can be understood by linearization of the equations around the equilibrium solution. Above the critical density we get a non-exponential relaxation to the final condensate value p^0 with |p(t)|-|p^0| ~1/t that holds for all densities. Furthermore we include the full self-consistent Hartree-Fock-Bogoliubov (HFB) terms due to the exciton-exciton interaction and the kinetics of the anomalous functions F_k= . The collision terms are analyzed and an approximation is used which is consistent with the existence of BEC. The inclusion of the coherent x-x interaction does not change the dephasing laws. The anomalous function F_k exhibits a clear threshold behaviour at the critical density.
description: European Physical Journal B (in print)
Additional file 2: of Development and validation of a simple screening tool for caregiver grief in dementia caregiving
Creators: name: Tau Ming Liew
name: Tai, Bee Choo
name: Yap, Philip
name: Koh, Gerald Choon-Huat
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Results on the goodness of fit and discriminative value of the final regression model. (DOCX 38 kb)
Search for supersymmetry in events with a photon, a lepton, and missing transverse momentum in proton-proton collisions at $\sqrt{s} =$ 13 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Results of a search for supersymmetry are presented using events with a photon, an electron or muon, and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 35.9 fb$^{-1}$ of proton-proton collisions at $\sqrt{s} =$ 13 TeV, produced by the LHC and collected with the CMS detector in 2016. Theoretical models with gauge-mediated supersymmetry breaking predict events with photons in the final state, as well as electroweak gauge bosons decaying to leptons. Searches for events with a photon, a lepton, and missing transverse momentum are sensitive probes of these models. No excess of events is observed beyond expectations from standard model processes. The results of the search are interpreted in the context of simplified models inspired by gauge-mediated supersymmetry breaking. These models are used to derive upper limits on the production cross sections and set lower bounds on masses of supersymmetric particles. Gaugino masses below 930 GeV are excluded at the 95% confidence level in a simplified model with electroweak production of a neutralino and chargino. For simplified models of gluino and squark pair production, gluino masses up to 1.75 TeV and squark masses up to 1.43 TeV are excluded at the 95% confidence level.
description: Replaced with the published version. Added the journal reference and the DOI. All the figures and tables can be found at http://cms-results.web.cern.ch/cms-results/public-results/publications/SUS-17-012 (CMS Public Pages)
Additional file 1: of Development and validation of a simple screening tool for caregiver grief in dementia caregiving
Creators: name: Tau Ming Liew
name: Tai, Bee Choo
name: Yap, Philip
name: Koh, Gerald Choon-Huat
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Further details on the evaluation of the final regression model in its goodness of fit and discriminative value. (DOCX 37 kb)
Cytoprotection by Amifostine during Autologous Stem Cell Transplantation for Advanced Refractory Hematologic Malignancies
Creators: name: Moore, Dominic T.
name: Gabriel, Don A.
name: Serody, Jonathan S.
name: Kirby, Suzanne L.
name: Shea, Thomas C.
name: Harvey, Donald
name: Krasnov, Carol
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: Abstract This study evaluated whether amifostine protects against mucositis and other toxicities in patients with advanced, refractory, or recurrent hematologic malignancies undergoing high-dose chemotherapy and total body irradiation. Thirty-five patients (20 with non-Hodgkin lymphoma, 12 with Hodgkin disease, and 3 with acute myelogenous leukemia) who underwent autologous stem cell transplantation were conditioned with total body irradiation 2 Gy twice daily on days −8 through −6; cyclophosphamide 6 g/m2, etoposide 1.8 g/m2, and carboplatin 1 g/m2 on days −5 through −3; and amifostine 500 mg/m2 on days −8 through −2. Prior institutional experience in patients treated without amifostine was used as a historical comparison (no-amifostine group). Severe mucositis occurred in 14 (40%) of 35 patients in the amifostine group, compared with 33 (94%) of 35 in the no-amifostine group (P < .0001). Total parenteral nutrition was used by 4 (11%) of 35 amifostine-treated patients and 34 (97%) of 35 no-amifostine patients (P < .0001). The median duration of narcotic use decreased from 15.5 days with no amifostine to 11 days with amifostine (P = .002). Granulocyte and platelet engraftment times were similar. Prospective trials with innovative designs and clearly defined stopping rules are warranted to confirm whether amifostine reduces the toxicities of a myelosuppressive conditioning regimen before autologous stem cell transplantation without compromising therapeutic response.
Pharmacokinetics of Ganciclovir after Oral Valganciclovir versus Intravenous Ganciclovir in Allogeneic Stem Cell Transplant Patients with Graft-versus-Host Disease of the Gastrointestinal Tract
Creators: name: Ratanatharathorn, Voravit
name: Emmanouilides, Christos
name: Shaw, Leslie M.
name: Gabriel, Don A.
name: Lange, W. Robert
name: Winston, Drew J.
name: Baden, Lindsey R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: AbstractThe pharmacokinetics of ganciclovir after oral valganciclovir versus intravenous ganciclovir were compared in allogeneic stem cell transplant recipients with stable graft-versus-host disease of the gastrointestinal tract. Twenty-two evaluable adult patients were randomized to receive a single dose of open-label study drug (900 mg of oral valganciclovir or 5 mg/kg of intravenous ganciclovir). After a washout period of 2 to 7 days, patients were crossed over to receive the alternate study drug. Ganciclovir and valganciclovir concentrations in plasma were measured over 24 hours after dosing. Noninferiority of 900 mg of valganciclovir relative to intravenous ganciclovir was concluded if the lower limit of the 1-sided 95% confidence interval of the ratio of least-square means of the ganciclovir area under the curve (AUC) for the 2 study drugs was >80%. Valganciclovir was found to be rapidly absorbed and converted into ganciclovir. The ganciclovir exposure after 900 mg of valganciclovir noninferior to that of intravenous ganciclovir (AUC0-∞, 52.1 and 53.8 μg·h/mL, respectively; 95% confidence interval of the ratio of least square means of AUC0-∞, 82.48%-118.02%). Oral valganciclovir could be a useful alternative to intravenous ganciclovir in certain stable stem cell transplant patients who require prophylaxis or preemptive therapy for cytomegalovirus infection.
Optimasi Penggunaan ChatGPT, SCISPACE, SCITE.AI Untuk Penulisan Artikel
Creators: name: Baharuddin, Baharuddin
Publisher: name: Universitas Surabaya
Year: 2024

description: Optimasi Penggunaan ChatGPT, SCISPACE, SCITE.AI Untuk Penulisan Artikel

Oleh: Baharuddin | Author | Researcher

Ringkasan

Kecerdasan artifisial hadir dengan "membawa" kemudahan, tantangan, dan sekaligus risiko. Pemahaman yang utuh akan meminimalkan risiko dan dampak negatif. Edukasi berkelanjutan adalah kunci memahami secara utuh penggunaan AI yag baik dan benar. Arahan ini tertuang dengan jelas oleh panduan yang dikeluarkan oleh UNESCO dan WHO.

Publikasi adalah bagian yang tidak terpisahkan dalam dunia akademik. Kemampuan menuliskan artikel dengan baik dan benar adalah kunci produktifitas publikasi ilmiah. Hadirnya AI menjadi solusi dan sekaligus tantangan.

Pada perspektif alat bantu publikasi, kita dapat menggunakan ChatGPT, SCISPACE, dan SCITE.AI. Teknologi pada aplikasi ini mampu mempercepat produksi tulisan dengan mengoptimalkan koreksi cepat dan sekaligus sebagai alat bantu interpretasi. Alat ini akan sangat bermanfaat jika didukung oleh kemampuan Author Checking yang "mumpuni."keyword: kecerdasan artifisial, chatgpt, scispace, scite.ai
Comment on "Critical currents in ballistic two-dimensional InAs-based superconducting weak links"
Creators: name: Bastian, G.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: In ballistic Josephson junctions the experimentally observed iv-characteristics deviate from the theoretically predicted behaviour. Recently, Heida et al. Phys. Rev. B 60, 13135 (1999) discussed this problem and offered an explanation for the discrepancy. Considering this explanation, several contradictions to the authors' data as well as to other publications are shown.
description: 4 pages, submitted to PRB on 1999-11-29, referee's reports have been collected until 2000-04-17, no reply recieved from editors until 2000-06-02
Additional file 3: of A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable
Creators: name: Cortellini, Alessio
name: Bersanelli, Melissa
name: Buti, Sebastiano
name: Cannita, Katia
name: Santini, Daniele
name: Perrone, Fabiana
name: Giusti, Raffaele
name: Tiseo, Marcello
name: Michiara, Maria
name: Marino, Pietro Di
name: Tinari, Nicola
name: Tursi, Michele De
name: Zoratto, Federica
name: Veltri, Enzo
name: Marconcini, Riccardo
name: Malorgio, Francesco
name: Russano, Marco
name: Anesi, Cecilia
name: Zeppola, Tea
name: Filetti, Marco
name: Marchetti, Paolo
name: Botticelli, Andrea
name: Cappellini, Gian Antonini
name: Galitiis, Federica De
name: Vitale, Maria
name: Rastelli, Francesca
name: Pergolesi, Federica
name: Berardi, Rossana
name: Rinaldi, Silvia
name: Tudini, Marianna
name: Silva, Rosa
name: Annagrazia Pireddu
name: Atzori, Francesco
name: Chiari, Rita
name: Ricciuti, Biagio
name: Giglio, Andrea De
name: Iacono, Daniela
name: Gelibter, Alain
name: Occhipinti, Mario
name: Parisi, Alessandro
name: Porzio, Giampiero
name: Fargnoli, Maria
name: Ascierto, Paolo
name: Ficorella, Corrado
name: Natoli, Clara
Publisher: name: figshare
Year: 2019
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Univariate and multivariate analyses with logistic regression of Objective Response Rate. (DOC 49 kb)
Risk Factor Analysis of Outcomes after Unrelated Cord Blood Transplantation in Patients with Hurler Syndrome
Creators: name: Szabolcs, Paul
name: Kurtzberg, Joanne
name: Prasad, Vinod K.
name: Ionescu, Irina
name: Rocha, Vanderson
name: Michel, Gerard
name: O'Meara, Anne
name: Aldenhoven, Mieke
name: Gluckman, Eliane
name: Boelens, Jaap Jan
name: Escolar, Maria
name: Wynn, Robert
name: Parikh, Suhag
name: Cavazzana-Calvo, Marina
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: AbstractAllogeneic stem cell transplantation (SCT) is considered effective in preventing disease progression in patients with Hurler syndrome (HS). Unrelated umbilical cord blood (UCB) grafts are suggested as an alternative to bone marrow (BM) or peripheral blood stem cells (PBSC). We studied 93 HS patients receiving an UCB graft to analyze risk factors for outcomes. The median time from diagnosis to transplant was 4.6 months, median follow-up was 29 months, and median number of nucleated CB cells infused was 7.6 × 107/kg. Most of the patients received 1 or 2 HLA disparate grafts, and the most frequently used conditioning regimen was cyclophosphamide + busulfan (Bu/Cy). All patients received anti-T cell antibody. At post transplant day +60, the cumulative incidence of neutrophil engraftment was 85%. A younger age at transplant and a higher CD34+ dose at infusion were favorably associated with engraftment. With the exception of 2 patients, all engrafted patients achieved full and sustained donor chimerism. The 3-year event-free survival (EFS) and 3-year overall survival (OS) rates were 70% and 77%, respectively. In a multivariate analyses, use of Bu/Cy and a shorter interval from diagnosis to transplant were predictors for improved EFS rate (82% for patients transplanted within 4.6 months after diagnosis compared to 57% for the rest). Improved outcomes from early transplantation and immediate availability of CB unit lead us to conclude that CB transplantation is a beneficial option, which should be considered expediently for children with HS.
Pulmonary, Gonadal, and Central Nervous System Status after Bone Marrow Transplantation for Sickle Cell Disease
Creators: name: Hardy, Karen
name: Adamkiewicz, Thomas
name: Sanders, Jean E.
name: Giller, Roger
name: Kamani, Naynesh
name: Levine, John E.
name: Ohene-Frempong, Kwaku
name: Hsu, Lewis L.
name: Bernaudin, Francoise
name: Rogers, Zora R.
name: Scott, J. Paul
name: Buchanan, George R.
name: Roberts, Irene A.G.
name: Dickerhoff, Roswitha
name: Patience, Melinda
name: Edwards, Sandie
name: Margolis, David
name: Redding-Lallinger, Rupa
name: Bunin, Nancy
name: Haut, Paul R.
name: Walters, Mark C.
name: Horan, John
name: Sullivan, Keith M.
name: Barkovich, James
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: We conducted a prospective, multicenter investigation of human-leukocyte antigen (HLA) identical sibling bone marrow transplantation (BMT) in children with severe sickle cell disease (SCD) between 1991 and 2000. To determine if children were protected from complications of SCD after successful BMT, we extended our initial study of BMT for SCD to conduct assessments of the central nervous system (CNS) and of pulmonary function 2 or more years after transplantation. In addition, the impact on gonadal function was studied. After BMT, patients with stroke who had stable engraftment of donor cells experienced no subsequent stroke events after BMT, and brain magnetic resonance imaging (MRI) exams demonstrated stable or improved appearance. However, 2 patients with graft rejection had a second stroke after BMT. After transplantation, most patients also had unchanged or improved pulmonary function. Among the 11 patients who had restrictive lung changes at baseline, 5 were improved and 6 had persistent restrictive disease after BMT. Of the 2 patients who had obstructive changes at baseline, 1 improved and 1 had worsened obstructive disease after BMT. There was, however, significant gonadal toxicity after BMT, particularly among female recipients. In summary, individuals who had stable donor engraftment did not experience sickle-related complications after BMT, and were protected from progressive CNS and pulmonary disease.
Additional file 1: of BRACAVENIR: an observational study of expectations and coping in young women with high hereditary risk of breast and ovarian cancer
Creators: name: Kwiatkowski, Fabrice
name: Gay-Bellile, Mathilde
name: Dessenne, Pascal
name: Laquet, Claire
name: Boussion, Véronique
name: Béguinot, Marie
name: Marie-Françoise Petit
name: Anne-Sophie Grémeau
name: Verlet, Céline
name: Chaptal, Charlotte
name: Broult, Marilyn
name: Jouvency, Sylvie
name: Duclos, Martine
name: Yves-Jean Bignon
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Table S1. Detail of scores by questionnaire and by completion time. (DOCX 21 kb)
Polarization amplitude near quantum critical points
Creators: name: Furuya, Shunsuke C.
name: Nakamura, Masaaki
Publisher: name: arXiv
Year: 2019
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We discuss the polarization amplitude of quantum spin systems in one dimension. In particular, we closely investigate it in gapless phases of those systems based on the two-dimensional conformal field theory. The polarization amplitude is defined as the ground-state average of a twist operator which induces a large gauge transformation attaching the unit amount of the U(1) flux to the system. We show that the polarization amplitude under the periodic boundary condition is sensitive to perturbations around the fixed point of the renormalization-group flow rather than the fixed point itself even when the perturbation is irrelevant. This dependence is encoded into the scaling law with respect to the system size. In this paper, we show how and why the scaling law of the polarization amplitude encodes the information of the renormalization-group flow. In addition, we show that the polarization amplitude under the antiperiodic boundary condition is determined fully by the fixed point in contrast to that under the periodic one and that it visualizes clearly the nontriviality of spin systems in the sense of the Lieb-Schultz-Mattis theorem.
Additional file 11 of Genomic and immunological profiles of small-cell lung cancer between East Asians and Caucasian
Creators: name: Lin, Anqi
name: Zhou, Ningning
name: Zhu, Weiliang
name: Zhang, Jiexia
name: Wei, Ting
name: Guo, Linlang
name: Luo, Peng
name: Zhang, Jian
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 11: Table S2. Related to Additional file 1: Fig. S1b. The results of the co-occurrence/mutual exclusivity of oncogenes/TSGs in the Caucasian cohort (Top20 mutated genes).