cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Is it possible to unify three kinds of Dark Matters into a Kaluza-Klein Neutrino?
Creators: name: Nishio, Sakiko G. J.
name: Bamba, Kazuharu
name: Sugamoto, Akio
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: A unified theory of including all kinds of dark matters into a single species (field) is discussed. In particular, it is considered that the Warm Dark matter (WDM), the existence of which may be required by the detailed $N$-body simulations of galaxies using the $Λ$CDM model, is the right-handed neutrino, the Hot Dark Matter (HDM) is the left-handed neutrino, and the Cold Dark Matter (CDM) is the first Kaluza-Klein (KK) mode of neutrino. The study on how to detect the first KK neutrino mode as CDM by LHC, SuperK, and IceCube is also explained. Not only these detectors but also the recent experiments, such as DAMA/LIBRA, PAMELA, XENON100, and XMASS as well as the various satellite detectors including Planck should be examined.
description: 17 pages, no figure
title: Systemic approach to the new 8-th edition of the TNM classification for lung cancer
Creators: name: Grigoryan, Marine
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Cancer
subject: Staging
subject: CT
subject: Lung

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1.Recognise the radiological features that correspond to each stage of lung cancer 2. Illustrate the staging features of lung cancer in some special cases 3.Know how to distinguish between some of the closely related radiological findings 4.Identify...
Refined and microlocal Kakeya-Nikodym bounds for eigenfunctions in two dimensions
Creators: name: Blair, Matthew D.
name: Sogge, Christopher D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: Classical Analysis and ODEs (math.CA)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We obtain some improved essentially sharp Kakeya-Nikodym estimates for eigenfunctions in two-dimensions. We obtain these by proving stronger related microlocal estimates involving a natural decomposition of phase space that is adapted to the geodesic flow.
description: 17 pages, 2 figures
Young Scientist Publication Committee Established
Creators: name: R. Ström
Publisher: name: Zenodo
Year: 2022
Subjects: WP2

description: The AIDAinnova young scientist publication committee ( has been established. This required defining the PubCom procedures as well as defining the PubCom composition. Subsequently, the corresponding reviewing procedures for a few key types of AIDAinnova documents (e. drafts, publications, conference proceedings, notes) were technically implemented in the CERN Document Server (Mailing lists for comm unication among young scientists from all AIDAinnova institutes were put in place. Junior and senior PubCom members have been appointed. Meanwhile the first AIDAinnova documents are undergoing PubCom review.
title: A dynamic pressure distribution model for ice pressure load patches used in numerical simulations
Creators: name: Lande Andrade, Sthéfano
Publisher: name: Memorial University of Newfoundland
Year: 2023

description: The work presents a model for ice load pressure patch representation in numerical structural simulation that captures the non-uniform pressure distribution as a function of the ice-structure interface shape. For this purpose, the first step of the work was the analysis of pressure data from ice impact experiments. This work presents the ice pressure distribution recorded and analysed in high temporal- and spatial-resolutions. The results show regions of high- and low-pressure zones (i.e., HPZ and LPZ) at the ice-indenter interface, which agree with previous works. Furthermore, based on the visual analysis of the pressure maps and ice specimen test faces, it was possible to hypothesise that the pattern assumed by the HPZ could be explained by the shape of the contact area. Based on this observation a geometric model for HPZ and LPZ representation over any contact area was developed and it is presented in this work for the first time. The methodology uses the topological skeleton and distance field information of the ice contact area’s shape to define the HPZ and LPZ associated to a contact area from the high-strain-rate interaction between an ice feature and a flat structure. The results from this methodology compare favourably with experimental observations of the HPZ distribution patterns. Finally, this led to the development of a new energy-coupled ice load model called NILAS (Non-uniform Ice Load Application System). The NILAS is capable of accounting for structural deformation energy during the simulation, while also generating non-uniform ice load pressure patches. The NILAS is designed for use in numerical structural simulations for the assessment of damage to non-polar class structures and overloaded polar class structures. While simpler methods that use uniform pressure patches with correction factors (e.g., IACS UR I) can approximate the effects of load concentration caused by HPZ, the NILAS model can directly include these regions of pressure concentration into the load patch. Therefore, the new model can account for the path-dependent plasticity associated with localized deformation response to the HPZ, which is of particular importance for non-ice class ships and overloaded ice-class ships.
Colocalization of Fast and Slow Timescale Dynamics in the Allosteric Signaling Protein CheY
Creators: name: Boyer, Joshua A.
name: Whitley, Matthew J.
name: McDonald, Leanna R.
name: Lee, Andrew L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: It is now widely recognized that dynamics are important to consider for understanding allosteric protein function. However, dynamics occur over a wide range of timescales, and how these different motions relate to one another is not well understood. Here, we report an NMR relaxation study of dynamics over multiple timescales at both backbone and side-chain sites upon an allosteric response to phosphorylation. The response regulator, Escherichia coli CheY, allosterically responds to phosphorylation with a change in dynamics on both the μs-ms timescale and ps-ns timescale. We observe an apparent decrease and redistribution of μs-ms dynamics upon phosphorylation (and accompanying Mg2+ saturation) of CheY. Additionally, methyl groups with the largest changes in ps-ns dynamics localize to the regions of conformational change measured by μs-ms dynamics. The limited spread of changes in ps-ns dynamics suggests a distinct relationship between motions on the μs-ms and ps-ns timescales in CheY. The allosteric mechanism utilized by CheY highlights the diversity of roles dynamics play in protein function.
Hinter dem Vorhang: Eine Vorzeichnung Johann Heinrich Rambergs für das Titelkupfer zu Goethes ‚Claudine von Villa Bella‘
Creators: name: Butera, Valeria
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: 700 Künste, Bildende Kunst allgemein

description: Der Beitrag befasst sich mit einer 1827 datierten aquarellierten Zeichnung von Johann Heinrich Ramberg (1793‒1840), welche ohne Hinweis auf ihren ursprünglichen Entstehungskontext als Neuerwerbung in die Grafische Sammlung des Deutschen Historischen Museums gelangte. Der Beitrag verfolgt die Entstehung der Zeichnung, die inzwischen in Verbindung zu einem wenig bekannten frühen Schauspiel des jungen Goethe, ‚Claudine von Villa Bella‘ (1776), gesetzt werden konnte. Parallel werden auch andere Fragen thematisiert: die Rolle des Künstlers als Buchillustrator der Goethe-Zeit, seine Tätigkeit für die Bühne sowie der Einfluss der italienischen Reise und des römischen Karnevals sowohl auf das Schauspiel Goethes als auch auf die Darstellung Rambergs.
Structural and Functional Analysis of the Human Nuclear Xenobiotic Receptor PXR in Complex with RXRα
Creators: name: Holman, Natalie S.
name: Talmage, Garrick
name: Wallace, Bret D.
name: Betts, Laurie
name: Redinbo, Matthew R.
name: Pollet, Rebecca M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The human nuclear xenobiotic receptor PXR recognizes a range of potentially harmful drugs and endobiotic chemicals, but must complex with the nuclear receptor RXRα to control the expression of numerous drug metabolism genes. To date, the structural basis and functional consequences of this interaction have remained unclear. Here we present 2.8 Å resolution crystal structures of the heterodimeric complex formed between the ligand binding domains (LBDs) of human PXR and RXRα. These structures establish that PXR and RXRα form a heterotetramer unprecedented in the nuclear receptor family of ligand-regulated transcription factors. We further show that both PXR and RXRα bind to the transcriptional coregulator SRC-1 with higher affinity when they are part of the PXR-RXRα heterotetramer complex than they do when each LBD is examined alone. Furthermore, we purify the full-length forms of each receptor from recombinant bacterial expression systems, and characterize their interactions with a range of direct and everted repeat DNA elements. Taken together, these data advance our understanding of PXR, the master regulator of drug metabolism gene expression in humans, in its functional partnership with RXRα.
Nonlinear coupler operating on Werner-like states - entanglement creation, its enhancement and preservation
Creators: name: Kowalewska-Kudłaszyk, A.
name: Leoński, W.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We discuss a model of two nonlinear Kerr-like oscillators, mutually coupled and excited by parametric process. We show that the system's evolution, starting from Werner-like states, remains closed within a small set of two-mode n-photon states the system, and pure two-qubit entangled state can be generated. For some initial Werner-like states delayed entanglement generation can be observed. We investigate the influence of two damping mechanisms on the system's evolution. We show that for the both cases, the entanglement can survive despite the presence of damping, and the effects of sudden entanglement death and its rebirth can appear in the system.
title: The role of CTA in the diagnosis of non-traumatic SAH. Leterature review
Creators: name: Grigoryan, Marine
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Aneurysms
subject: Computer Applications-3D
subject: CT-Angiography
subject: CT
subject: Emergency

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review computed tomography (CT) appearance of SAH To review and emphasize the importance of computed tomography angiography (CTA) of SAH To assess the role of CTA in the diagnosis of non-traumatic...
title: Stellungnahme zum Deutschen Zentrum für Altersfragen e.V. (DZA), Berlin
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2023
Subjects: Evaluation
Ressortforschung
Forschungsinfrastrukturen
Transfer
Altersforschung
Bundesministerium für Familie
Politikberatung

description: Das Deutsche Zentrum für Altersfragen (DZA) mit Sitz in Berlin ist als eingetragener Verein privatrechtlich organisiert und zählt damit zu den sogenannten ressortforschungsähnlichen Einrichtungen. Als solche erfüllt das DZA Aufgaben für das Bundesministerium für Familie, Senioren, Frauen und Jugend (BMFSFJ). Das DZA verknüpft dabei insbesondere Altersforschung, Politikberatung und Leistungen einer Forschungsdateninfrastruktur. Im Mittelpunkt der Arbeiten des DZA steht die Lebenslage alternder und alter Menschen. Es bearbeitet Fragen des Alters als Lebensphase sowie des Alterns als Prozess.
Structure and Function of Palladin's Actin Binding Domain
Creators: name: Mohiuddin, Jahan
name: Campbell, Sharon L.
name: Beam, Matthew T.
name: Otey, Carol A.
name: Dixon, Richard D.S.
name: Murphy, Grant S.
name: Brungardt, Joseph G.
name: Goicoechea, Silvia M.
name: Beck, Moriah R.
name: Srinath, Pavan
name: Patel, Julie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Here we report the NMR structure of the actin-binding domain contained in the cell adhesion protein palladin. Previously we demonstrated that one of the immunoglobulin domains of palladin (Ig3) is both necessary and sufficient for direct F-actin binding in vitro. In this study, we identify two basic patches on opposite faces of Ig3 that are critical for actin binding and crosslinking. Sedimentation equilibrium assays indicate that the Ig3 domain of palladin does not self-associate. These combined data are consistent with an actin crosslinking mechanism that involves concurrent attachment of two actin filaments by a single palladin molecule by an electrostatic mechanism. Palladin mutations that disrupt actin binding show altered cellular distributions and morphology of actin in cells, revealing a functional requirement for the interaction between palladin and actin in vivo.
title: Serous cystic neoplasm of the pancreas: comparison of endoscopic ultrasonographic features of surgically removed cases with computed tomography and magnetic resonance imaging
Creators: name: Hwang, Hyeonseung
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Abdomen
subject: Pancreas
subject: Ultrasound
subject: CT
subject: MR
subject: Endoscopy
subject: Surgery
subject: Cysts
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Recently, as the accessibility to radiologic examination such as computed tomography (CT), magnetic resonance imaging (MRI), and ultrasonography (US) has expanded, the detection rates of asymptomatic cystic lesions of the pancreas has...
title: Leitfaden der institutionellen Evaluation von Einrichtungen mit Ressortforschungsaufgaben des Bundes
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2023
Subjects: Evaluation
Ressortforschung
Forschungsinfrastrukturen
Digitalisierung
Forschung
Politikberatung
Wissenschaftskommunikation

description: Der Leitfaden der institutionellen Evaluation von Einrichtungen mit Ressortforschungsaufgaben des Bundes erläutert Grundsätze, Verfahren und Kriterien zur Begutachtung entsprechender Institutionen durch den Wissenschaftsrat. Er dient zur Orientierung der Arbeitsgruppen, die der Evaluationsausschuss des Wissenschaftsrats für die institutionellen Evaluationen dieser Einrichtungen einsetzt.
A search for water masers associated with class II methanol masers - I. Longitude range 6 to 20 degrees
Creators: name: Titmarsh, A. M.
name: Ellingsen, S. P.
name: Breen, S. L.
name: Caswell, J. L.
name: Voronkov, M. A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The Australia Telescope Compact Array has been used to search for 22-GHz water masers towards the 119 6.7-GHz methanol masers detected in the Methanol Multi-Beam survey between Galactic longitudes 6 and 20 degrees; we find water masers associated with 55 (~46 per cent). Methanol masers with associated water masers have a higher mean integrated luminosity than those without and there is a general trend for sources with more luminous 6.7-GHz methanol masers to be associated with more luminous water maser emission. We have inspected the GLIMPSE three colour images of the regions surrounding the masers and cross-matched the maser positions with existing catalogues of Extended Green Objects and Infrared Dark Clouds. We find more Extended Green Objects at sites where both methanol and water masers are present than at sites with only methanol masers, but no significant difference in the fraction embedded within Infrared Dark Clouds. Analysis of the 1.1-mm dust emission shows dust clumps associated with masers that have greater flux densities and higher column densities than those without. Dust clumps associated with both water and 6.7-GHz methanol masers are generally the most compact clumps followed by those associated with only methanol then the clumps without associated maser emission. We conclude that protostars with both methanol and water masers are often older than those with only methanol, however, we suggest that the evolutionary phase traced by water masers is not as well defined as for 6.7-GHz methanol masers.
description: To be published in the Monthly Notices of the Royal Astronomical Society
Work plan inclusive of the detailed programme announced in MS10.1 (MS41)
Creators: name: Calderini, Giovanni
name: Vos, Marcel
name: Petagna, Paolo
Publisher: name: Zenodo
Year: 2022
Subjects: WP10

description: The document describes the agreed plan of action for the Task 10.3 “Development of advanced engineered solutions for the hydraulic interconnection of multiple micro-structured silicon cold plates”. The planned R&D activities aim at different objectives: Review existing results in the use of PEEK for 3D printed connectors, obtained in the first year of AIDAinnova but also by other projects) and produce PEEK prototypes with improved printing techniques. Develop 3D printing on different materials and compare with the available results on PEEK. Improve the design of the prototype connectors to optimize it to the features of the used materials and in synergy with Task 10.2.
title: Strukturen der Forschungsfinanzierung an deutschen Hochschulen | Positionspapier
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2022
Subjects: Forschungsfinanzierung
Hochschulfinanzierung
Drittmittel
Fachhochschulen
Universitäten
Förderverfahren
Wissenschaftssystem

description: Die Finanzierung von Forschung an Hochschulen ist an Grenzen gekommen: Umfangreiche Mittel aus den Grundhaushalten müssen dafür eingesetzt werden, die Durchführung von Drittmittelprojekten zu ermöglichen. Dies geht zu Lasten der Aufgaben der Grundfinanzierung, die der Wissenschaftsrat in seinem Positionspapier klar definiert. Vor diesem Hintergrund tritt das Beratungsgremium von Bund und Ländern für eine Neujustierung von Grund- und Projektfinanzierung ein und gibt dazu Empfehlungen. Auch die administrativen und rechtlichen Rahmenbedingungen von Forschungsfinanzierung werden in den Blick genommen. Auf diese Weise will der Wissenschaftsrat dazu beitragen, dass Forschungsfinanzierung an deutschen Hochschulen krisenfester wird und auch in schwierigen Zeiten weiter exzellente Forschung zum Wohl unserer Gesellschaft durchgeführt werden kann.
Locating European Citizenship
Creators: name: Moro, Giovanni
Publisher: name: Universita' degli Studi di Salerno
Year: 2020
Subjects: Citizenship
European citizenship
European Union

description: This paper is not devoted to European citizenship, but rather to the ways we study it. The paper is based on a sample of recent literature on EU citizenship and is developed as follows. Firstly, seven divergent thematizations (the ways EU citizenship is identified and framed) are introduced and analyzed with regard to the problems they show. Then five conceptualizations are presented that come from the same sources, and that should be considered to overcome criticalities. There follows the introduction of a conceptual framework regarding democratic citizenship as an empirical phenomenon. This framework allows the identification of a paradigm that has shaped national citizenship and that is experiencing deep crisis and transformation. European citizenship, from this perspective, can be viewed as anomaly of the paradigm and then appropriately studied.
title: Validation and clinical utility of multiphase flat detector CTA for triage to endovascular stroke therapy
Creators: name: Schregel, Katharina
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: CNS
subject: Neuroradiology brain
subject: Vascular
subject: Catheter arteriography
subject: Diagnostic procedure
subject: Acute
subject: Ischaemia / Infarction

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Collateral circulation has pivotal impact on outcome in endovascularly treated patients with acute ischemic stroke (AIS)[1]. Various collateral scoring systems have been established [2–4] and are used to predict infarct size [5] or treatment...
Cu,Zn-Superoxide Dismutase without Zn Is Folded but Catalytically Inactive
Creators: name: Alexandrova, Anastassia N.
name: Proctor, Elizabeth A.
name: Redler, Rachel L.
name: Nedd, Sean
name: Dokholyan, Nikolay V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Amyotrophic Lateral Sclerosis has been linked to the gain of aberrant function of superoxide dismutase, Cu,Zn-SOD1 upon protein misfolding. The mechanism of SOD1 misfolding is thought to involve mutations leading to the loss of Zn, followed by protein unfolding, and aggregation. We show that the removal of Zn from SOD1 may not lead to an immediate unfolding, but immediately deactivates the enzyme through a combination of subtle structural and electronic effects. Using Quantum Mechanics/Discrete Molecular Dynamics, we showed that Zn-less wild type SOD1 and its D124N mutant that does not bind Zn both have at least metastable folded states. In those states, the reduction potential of Cu increases, leading to the presence of detectable amounts of Cu(I) instead of Cu(II) in the active site, as confirmed experimentally. The Cu(I) protein cannot participate in the catalytic Cu(I) – Cu(II) cycle. However, even without the full reduction to Cu(I), the Cu site in the Zn-less variants of SOD1 is shown to be catalytically incompetent: unable to bind superoxide in a way comparable to the wild type SOD1. The changes are more radical and different in the D124N Zn-less mutant than in the Zn-less wild type SOD1, suggesting D124N being perhaps not the most adequate model for Zn-less SOD1. Overall, Zn in SOD1 appears to be influencing the Cu site directly by adjusting its reduction potential and geometry. Thus, the role of Zn in SOD1 is not just structural, as was previously thought; it is a vital part of the catalytic machinery.
Psychosocial working conditions and mental health of medical assistants in Germany: A scoping review
Creators: name: Stiedenroth, Kira
name: Mambrey, Viola
name: Dreher, Annegret
name: Loerbroks, Adrian
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Public Health
subject: Mental and Social Health
subject: Medicine and Health Sciences
subject: Germany
subject: medical assistants
subject: mental health
subject: psychosocial working conditions
subject: scoping review

description: Scoping review protocol.
title: Imaging end stage renal failure patients with arteriovenous fistulas and haemodialysis grafts. The value of ultrasound.
Creators: name: Cokkinos, Demosthenes
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Ultrasound
subject: Vascular
subject: Arterial access
subject: Fistula

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review the indications for sonographic evaluation of upper extremity fistulas and dialysis grafts. To describe the examination technique using B mode, Colour and Spectral Doppler...
Rates of decay in the classical Katznelson-Tzafriri theorem
Creators: name: Seifert, David
Publisher: name: arXiv
Year: 2014
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: Given a power-bounded operator $T$, the theorem of Katznelson and Tzafriri states that $\|T^n(I-T)\|\to0$ as $n\to\infty$ if and only if the spectrum $σ(T)$ of $T$ intersects the unit circle $\mathbb{T}$ in at most the point 1. This paper investigates the rate at which decay takes place when $σ(T)\cap\mathbb{T}=\{1\}$. The results obtained lead in particular to both upper and lower bounds on this rate of decay in terms of the growth of the resolvent operator $R(\mathrm{e}^{\mathrm{i}θ},T)$ as $θ\to0$. In the special case of polynomial resolvent growth, these bounds are then shown to be optimal for general Banach spaces but not in the Hilbert space case.
description: 24 pages, to appear in Journal d'Analyse Math\'ematique
EPQ – REQUIREMENT NO.2
Creators: name: Levointurier-Vajda, Cloé
name: Sefkow, Felix
Publisher: name: Zenodo
Year: 2022
Subjects: WP1

description: According to AIDAinnova ethics requirement n°2, the applicant must demonstrate that appropriate health and safety procedures conforming to relevant local/national guidelines/legislation are followed for staff involved in this project. This deliverable confirms that appropriate health and safety measures procedures are implemented.
Hardouin & Hargreaves 2023 PRSB - Supplementary Material from Mapping nationally- and globally-at-risk species to identify hotspots for (and gaps in) conservation
Creators: name: Hardouin, Marie E.
name: Hargreaves, Anna L.
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Details on map digitization and beta-regression methods, and a supplementary analysis on species habitat protection
The Microbiota, Chemical Symbiosis, and Human Disease
Creators: name: Redinbo, Matthew R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Our understanding of mammalian-microbial mutualism has expanded by combing microbial sequencing with evolving molecular and cellular methods, and unique model systems. Here, the recent literature linking the microbiota to diseases of three of the key mammalian mucosal epithelial compartments – nasal, lung and gastrointestinal (GI) tract – is reviewed with a focus on new knowledge about the taxa, species, proteins and chemistry that promote health and impact progression toward disease. The information presented is further organized by specific diseases now associated with the microbiota:, Staphylococcus aureus infection and rhinosinusitis in the nasal-sinus mucosa; cystic fibrosis (CF), chronic obstructive pulmonary disorder (COPD), and asthma in the pulmonary tissues. For the vast and microbially dynamic GI compartment, several disorders are considered, including obesity, atherosclerosis, Crohn’s disease, ulcerative colitis, drug toxicity, and even autism. Our appreciation of the chemical symbiosis ongoing between human systems and the microbiota continues to grow, and suggest new opportunities for modulating this symbiosis using designed interventions.
title: A snapshot of CEUS-guided biopsy of liver target lesions in field practice of ultrasound interventional centres: a multicenter retrospective study
Creators: name: Francica, Giampiero
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Interventional non-vascular
subject: Liver
subject: Ultrasound
subject: Biopsy

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: In the recently issued EFSUMB guidelines the use CEUS-guided biopsy is adviced in deep abdominal organs (mainly liver) to avoid necrotic areas or improve targeting of undetectable or not conspicuous lesion targets on B-mode US (1,2) These...
Possible unconventional superconductivity in substituted BaFe$_{2}$As$_{2}$ revealed by magnetic pair-breaking studies
Creators: name: Rosa, P. F. S.
name: Adriano, C.
name: Garitezi, T. M.
name: Piva, M. M.
name: Mydeen, K.
name: Grant, T.
name: Fisk, Z.
name: Nicklas, M.
name: Urbano, R. R.
name: Fernandes, R. M.
name: Pagliuso, P. G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The possible existence of a sign-changing gap symmetry in BaFe$_{2}$As$_{2}$-derived superconductors (SC) has been an exciting topic of research in the last few years. To further investigate this subject we combine Electron Spin Resonance (ESR) and pressure-dependent transport measurements to investigate magnetic pair-breaking effects on BaFe$_{1.9}M_{0.1}$As$_{2}$ ($M=$ Mn, Co, Cu, and Ni) single crystals. An ESR signal, indicative of the presence of localized magnetic moments, is observed only for $M=$ Cu and Mn compounds, which display very low SC transition temperature ($T_{c}$) and no SC, respectively. From the ESR analysis assuming the absence of bottleneck effects, the microscopic parameters are extracted to show that this reduction of $T_{c}$ cannot be accounted by the Abrikosov-Gorkov pair-breaking expression for a sign-preserving gap function. Our results reveal an unconventional spin- and pressure-dependent pair-breaking effect and impose strong constraints on the pairing symmetry of these materials.
title: Detection of Pneumoperitoneum in digital radiography: Comparison of Chest and Abdominal radiography by position.
Creators: name: JEON, CHANG KYU
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Acute
subject: Comparative studies
subject: PACS
subject: Digital radiography
subject: Gastrointestinal tract
subject: Abdomen
subject: Peritoneum

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The golden standard for diagnosing pneumoperitoneum (PP) in digital radiography is known as Standing Chest PA radiography. However, Chest PA radiography of patients who will be taken immediately after endoscopy or surgery may be replaced with a...
Discovery of relatively hydrogen-poor giants in the Galactic globular cluster Omega Centauri
Creators: name: Hema, B. P.
name: Pandey, Gajendra
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: In this letter, the results of our low-resolution spectroscopic survey for identifying the hydrogen-deficient (H-deficient) stars in the red giant sample of the globular cluster Omega Cen are reported. Spectral analyses were carried out on the basis of the strengths of (0,0) MgH band and the Mg b triplet. In our sample, four giants were identified with weak/absent MgH bands in their observed spectra not as expected for their well determined stellar parameters. The Mg abundances for the program stars were determined from subordinate lines of the MgH band to the blue of the Mg b triplet, using the spectral synthesis technique. The derived Mg abundances for the program stars were as expected for the red giants of Omega Cen (Norris & Da Costa 1995), except for the four identified candidates. Determined Mg abundances of these four candidates are much lower than that expected for the red giants of Omega Cen, and are unacceptable based on the strengths of Mg b triplet in their observed spectra. Hence, the plausible reason for the weak/absent MgH bands in the observed spectra of these stars is a relatively lower abundance of hydrogen in their atmospheres. These giants may belong to the group of helium enriched red giants of Omega Cen.
description: 13 pages, 3 figures, Accepted for publication in ApJ Letters
title: FDG in pet-ct: review
Creators: name: Grigoryan, Marine
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Cancer
subject: Radiation therapy / Oncology
subject: PET-CT
subject: Hybrid Imaging

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1.Recognize what is FDG 2.Discuss indications of FDG 3.Show physiological and pathological distribution of...
POPD – REQUIREMENT NO.1
Creators: name: Yacoubi, Sabrina El
Publisher: name: Zenodo
Year: 2022
Subjects: WP1

description: According to the requirement n°1, AIDAinnova has the obligation to provide with a detailed plan for the Protection of Personal Data for the management of the project. As host institution, CERN is in charge of providing such deliverable and appointing a Data Protection Officer (DPO) for the entire project and consortium.
A Direct Interaction with RNA Dramatically Enhances the Catalytic Activity of the HIV-1 Protease In Vitro
Creators: name: Lee, Sook-Kyung
name: Swanstrom, Ronald
name: Ragland, Debra
name: Schiffer, Celia A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The mechanisms regulating HIV-1 protease (PR) activity are poorly understood.RNA accelerates cleavage of multiple substrates, regardless of RNA-binding ability.The HIV-1 PR can interact with nucleic acid to increase its catalytic efficiency.The interaction is primarily electrostatic, but size/structural determinants exist.Interactions between the HIV-1 PR and RNA could affect PR activity in the virion.Though the steps of human immunodeficiency virus type 1 (HIV-1) virion maturation are well documented, the mechanisms regulating the proteolysis of the Gag and Gag-Pro-Pol polyproteins by the HIV-1 protease (PR) remain obscure. One proposed mechanism argues that the maturation intermediate p15NC must interact with RNA for efficient cleavage by the PR. We investigated this phenomenon and found that processing of multiple substrates by the HIV-1 PR was enhanced in the presence of RNA. The acceleration of proteolysis occurred independently from the substrate's ability to interact with nucleic acid, indicating that a direct interaction between substrate and RNA is not necessary for enhancement. Gel-shift assays demonstrated the HIV-1 PR is capable of interacting with nucleic acids, suggesting that RNA accelerates processing reactions by interacting with the PR rather than the substrate. All HIV-1 PRs examined have this ability; however, the HIV-2 PR does not interact with RNA and does not exhibit enhanced catalytic activity in the presence of RNA. No specific sequence or structure was required in the RNA for a productive interaction with the HIV-1 PR, which appears to be principally, though not exclusively, driven by electrostatic forces. For a peptide substrate, RNA increased the kinetic efficiency of the HIV-1 PR by an order of magnitude, affecting both turnover rate (kcat) and substrate affinity (Km). These results suggest that an allosteric binding site exists on the HIV-1 PR and that HIV-1 PR activity during maturation could be regulated in part by the juxtaposition of the enzyme with virion-packaged RNA.
title: Is the 2017 version of LI-RADS better? Discussing changes to the algorithm and patient management implications
Creators: name: Goicea, Mihaela
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Liver
subject: Abdomen
subject: CT
subject: MR
subject: Diagnostic procedure
subject: Decision analysis
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: This poster aims to bring the 2017 version of LI-RADS to attention, in order to help radiologists maintain congruence of daily reports to internationally accepted standards. We illustrate with cases from our own hospital the features and categories...
title: Ausgestaltung der Promotion im deutschen Wissenschaftssystem | Positionspapier
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2023
Subjects: Promotion
Qualifizierungsphase
Universitäten
Karrierewege
Wissenschaftssystem
Wissenschaftlicher Nachwuchs
Promotionsdauer

description: Die Promotionspraxis im deutschen Wissenschaftssystem ist durch viele fachkulturelle Besonderheiten und unterschiedliche strukturelle und institutionelle Kontexte geprägt. Diese Diversifizierung ist eine Herausforderung für die Wahrung einheitlicher wissenschaftlicher Standards und muss daher reflektiert werden. In seinem Positionspapier zur Ausgestaltung der Promotion nimmt der Wissenschaftsrat zunächst eine Bestandsaufnahme vor. Ausgehend von dem Grundsatz, dass die eigenständige Forschung weiterhin den Kern der Promotion bilden muss, gibt er differenzierte Empfehlungen zur Durchführung von Promotionen wie auch zur Finanzierung und Beschäftigung von Doktorandinnen und Doktoranden.
Convective flow of sisko fluid over a bidirectional stretching sheet
Creators: name: Munir, Asif
name: Shahzad, Azeem
name: Khan, Masood
Publisher: name: arXiv
Year: 2014
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences
subject: 76A05

description: The present investigation discusses the flow and heat transfer characteristics of a steady three dimensional Sisko fluid. The flow is induced due to bidirectional stretching sheet. The influence of power-law index and stretching ratio on flow and heat transfer is studied thoroughly. Governing partial differential equations are reduced to coupled ordinary differential equations by suitable similarity variable. The resulting equations are then solved numerically by shooting method using adaptive Runge Kutta algorithm in combination with Broyden's method in the domain . The numerical results for the velocity and temperature fields are graphically presented and effects of the relevant parameters are discussed in detail. Moreover, the skin-friction coefficient and local Nusselt number for different values of the power-law index and stretching ratio are presented through tabulated data. The numerical results are verified with the results obtained by HAM. Additionally, the results are also validated with previously published pertinent literature as a special case of the problem.
description: 14 pages
title: Diffusion-Weighted Imaging in Primary Sclerosing Cholangitis: advantages and limitations
Creators: name: Chambenois, Edouard
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Abdomen
subject: Liver
subject: Biliary Tract / Gallbladder
subject: Imaging sequences
subject: Inflammation
subject: MR-Cholangiography

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To illustrate Diffusion Weighted MR imaging features of Primary Sclerosing Cholangitis. To discuss additional value of diffusion weighted imaging in PSC. To discuss limitations of...
Analysis of innovations needed in markets and technologies
Creators: name: Marini, Margherita
name: Ramos, Filipe
Publisher: name: Zenodo
Year: 2022
Subjects: WP2

description: This report provides an overview of market-innovation trends of particle detectors, both by technology and by market application, as well as a summary of key policymaking initiatives that will impact the market. The methodology used in the first section is a combination of market research, patent database analysis, and market survey with AIDAinnova participants industry participants. The second part of the report summarises recent policymaking initiatives affecting the market, with a particular focus on semiconductors.
Restoration of NBD1 Thermal Stability Is Necessary and Sufficient to Correct ∆F508 CFTR Folding and Assembly
Creators: name: Yang, Zhengrong
name: Brouillette, Christie G.
name: Cui, Liying
name: Aleksandrov, Andrei A.
name: He, Lihua
name: An, Jianli
name: Riordan, John R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: CFTR (ABCC7), unique among ABC exporters as an ion channel, regulates ion and fluid transport in epithelial tissues. Loss of function due to mutations in the cftr gene causes cystic fibrosis (CF). The most common CF-causing mutation, the deletion of F508 (ΔF508) from the first nucleotide binding domain (NBD1) of CFTR, results in misfolding of the protein and clearance by cellular quality control systems. The ΔF508 mutation has two major impacts on CFTR: reduced thermal stability of NBD1 and disruption of its interface with membrane-spanning domains (MSDs). It is unknown if these two defects are independent and need to be targeted separately. To address this question we varied the extent of stabilization of NBD1 using different second site mutations and NBD1 binding small molecules with or without NBD1/MSD interface mutation. Combinations of different NBD1 changes had additive corrective effects on ΔF508 maturation that correlated with their ability to increase NBD1 thermostability. These effects were much larger than those caused by interface modification alone and accounted for most of the correction achieved by modifying both the domain and the interface. Thus, NBD1 stabilization plays a dominant role in overcoming the ΔF508 defect. Furthermore, the dual target approach resulted in a locked-open ion channel that was constitutively active in the absence of the normally obligatory dependence on phosphorylation by protein kinase A. Thus, simultaneous targeting of both the domain and the interface, as well as being non-essential for correction of biogenesis, may disrupt normal regulation of channel function.
title: Post-procedural quality of life in patients underwent uterine artery embolisation (UAE) through transradial vs transfemoral approach: preliminary results
Creators: name: Basile, Antonio
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Interventional non-vascular
subject: Genital / Reproductive system female
subject: Pelvis
subject: Fluoroscopy
subject: MR
subject: Ultrasound
subject: Embolisation

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Uterine fibroids, also called myoma or leiomyoma, are the most common benign tumors of the female reproductive tract (1) and present in more than 40 % of women 40 years of age (2). They arise from the uterine smooth muscular tissue of myometrium and...
Non-Linear Trans-Planckian Corrections of Spectra due to the Non-trivial Initial States
Creators: name: Yusofi, E.
name: Mohsenzadeh, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Recent Planck results motivated us to use non-Bunch-Davies vacuum. In this paper, we use the excited-de Sitter mode as non-linear initial states during inflation to calculate the corrected spectra of the initial fluctuations of the scalar field. First, we consider the field in de Sitter space-time as background field and for the non-Bunch-Davies mode, we use the perturbation theory to the second order approximation. Also, unlike conventional renormalization method, we offer de Sitter space-time as the background instead Minkowski space-time. This approach preserve the symmetry of curved space-time and stimulate us to use excited mode. By taking into account this alternative mode and the effects of trans-Planckian physics, we calculate the power spectrum in standard approach and Danielsson argument. The calculated power spectrum with this method is finite, corrections of it is non-linear, and in de Sitter limit corrections reduce to linear form that obtained from several previous conventional methods.
description: 6 pages, Published in Physics Letters B
title: Can we identify the saw in dismemberment cases? Results of a microCT-based morphometric flow-chart
Creators: name: Giraudo, Chiara
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Forensic / Necropsy studies
subject: Cone beam CT
subject: Experimental investigations
subject: Forensics

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The tools used in cases of dismemberment cause specific marks, defined tool marks, on the victims [1,2]. Saws, which are considered complex tools, can cause marks on the bone which are usually defined as “false starts” and are characterized by...
How Diverse--CD4 Effector T Cells and their Functions
Creators: name: Wan, Y. Y.
name: Flavell, R. A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: CD4 effector T cells, also called helper T (Th) cells, are the functional cells for executing immune functions. Balanced immune responses can only be achieved by proper regulation of the differentiation and function of Th cells. Dysregulated Th cell function often leads to inefficient clearance of pathogens and causes inflammatory diseases and autoimmunity. Since the establishment of the Th1–Th2 dogma in the 1980s, different lineages of effector T cells have been identified that not only promote but also suppress immune responses. Through years of collective efforts, much information was gained on the function and regulation of different subsets of Th cells. In this review, we attempt to sample the essence of what has been learnt in this field over the past two decades. We will discuss the classification and immunological functions of effector T cells, the determinants for effector T cell differentiation, as well as the relationship between different lineages of effector T cells.
A Synonym Based Approach of Data Mining in Search Engine Optimization
Creators: name: Arora, Palvi
name: Bhalla, Tarun
Publisher: name: arXiv
Year: 2014
Subjects: subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: In todays era with the rapid growth of information on the web, makes users turn to search engines as a replacement of traditional media. This makes sorting of particular information through billions of webpages and displaying the relevant data makes the task tough for the search engine. Remedy for this is SEO i.e. having a website optimized in such a way that it will display the relevant webpages based on ranking. This is the main reason that makes search engine optimization a prominent position in online world. This paper present a synonym based data mining approach for SEO that makes the task of improving the ranking of the website much easier way and user will get answer to their query easily through any of search engine available in market.
description: 5 pages, 2figures, Published with International Journal of Computer Trends and Technology (IJCTT)
title: Multiparametric breast ultrasound: a simple, quantitative classification algorithm for the differentiation of benign from malignant lesions
Creators: name: Kapetas, Panagiotis
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Breast
subject: Ultrasound
subject: Elastography
subject: Ultrasound-Spectral Doppler
subject: Decision analysis
subject: Biopsy
subject: Contrast agent-intravenous
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Ultrasound (US) is a valuable adjunct to mammography for the detection and characterization of breast lesions. However, its inter-reader agreement is generally moderate while the diagnostic accuracy is highly variable (1). Classification algorithms...
title: Stellungnahme zum Julius Kühn-Institut – Bundesforschungsinstitut für Kulturpflanzen (JKI), Quedlinburg
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2023
Subjects: Evaluation
Forschungseinrichtungen
Kulturpflanzen
Pflanzenzüchtung
Pflanzenschutz
Ernährungssicherung
BMEL

description: Das Julius Kühn-Institut - Bundesforschungsinstitut für Kulturpflanzen forscht auf den Gebieten Pflanzengenetik, Pflanzenbau, Pflanzenernährung, Pflanzenschutz und Pflanzengesundheit. Es berät das Bundesministerium für Ernährung und Landwirtschaft sowie die Bundesregierung zu allen Fragen mit Bezug zu Kulturpflanzen. Hierbei zeichnet es sich durch überwiegend sehr gute Forschungsleistungen und hervorragende Transferleistungen aus. Der Wissenschaftsrat betont die sehr hohe Relevanz, die das JKI vor dem Hintergrund des Klimawandels und des Verlusts von Biodiversität hat.