cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Development of Plant-Based Burger Patties Using Vegan Staples Like Tofu and Tempeh: An Exploration Study Among the Young Adults
Creators: name: Thwe, Shwe Yi
name: Au, Deloris Jo Ey
name: Tan, Kiat Liang
name: Neo, Yun Ping
name: Chew, Lye Yee
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Plant Biology

description: This study aims to develop plant-based burger patties using tofu and tempeh with young adults as the targeted consumers. Samples consisted of different amount of tofu and tempeh were formulated with chicken breast meat as the control. All samples were subjected to consumer acceptance tests and physical and proximate analyses. Results show that panelists preferred patties with tofu to tempeh formulated at a 70:30 ratio. The plant-based patties and meat control had significantly different (p < 0.05) proximate composition from each other, with a notably high calcium content present in the plant-based sample. Sensory acceptance test showed that the developed plant-based burger patties were less appreciated than meat control by the consumers in overall acceptability, which can be alleviated through communication on the sustainability and health benefits.
Priscus/Crispus, Priscillianus/Crispinianus, and Benedicta, martyrs of Rome under the emperor Julian
Creators: name: Admin, CSLA
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: All evidence related to Priscus/Crispus, Priscillianus/Crispinianus, and Benedicta, martyrs of Rome under the emperor Julian.
Choosing a Rhetoric of the Enemy: Kenneth Burke's Comic Frame, Warrantable Outrage, and the Problem of Scapegoating
Creators: name: Desilet, Gregory
Publisher: name: Humanities Commons
Year: 2011
Subjects: subject: Rhetoric
subject: Burke, Kenneth, 1897-1993
subject: Conflict management--Study and teaching (Higher)

description: Kenneth Burke's dramatistic theory of rhetoric presents a significant tension between an “Iron Law of History” and a “comic” attitude. Comic framing in ironic awareness of one's own shortcomings in a conflict, as well as those of one's opponent, moderates aggression but also appears to dissolve the ground for the identification and censure of wrongdoing. Nevertheless, this did not prevent Burke from engaging in the censure of wrongdoing. Although Burke does not explicitly and adequately counter the apparent inconsistency, he implicitly provides a meta-perspective advancing a possible resolution. Forceful scapegoating of scapegoating itself, through comic irony and double-visioned analysis, can guide, in serial progression, warfare and redemptive reunion. Wartime speeches of Franklin D. Roosevelt illustrate the larger comic framing inherent in a rhetorical movement from “factional tragedy” to “comic” regard and reconciliation.
Effects of heavy metal exposure on hearing loss among shipyard personnel
Creators: name: Schaal, Nicholas Cody
name: Slagley, Jeremy
name: Zreiqat, Majed
name: Paschold, Helmut
Publisher: name: F1000Research
Year: 2017

description: Background
Studies suggest metal and solvent exposure may damage hearing. This study evaluated the association between exposures classified as high for metals, solvents, and noise on permanent threshold shift (PTS) development.

Methods
A total of 1,546 personnel at an industrial shipyard were divided into five exposure groups based on level of concentration: high noise, high metals/solvents, high metals/noise, high metals/solvents/noise, and a low metals/solvents/noise reference group. Hearing threshold changes were analyzed to identify development of a PTS.

Results
Logistic regression indicated high metals/solvents and high metals/solvent/noise groups had significantly greater odds ratios of 2.4; 95%CI [1.02, 2.85] and 1.7; 95%CI [1.46, 3.94], respectively, compared to a reference group. Both groups were associated with PTSs while controlling for age, gender, and exposure duration.

Conclusions
Simultaneous exposures classified as high for metals and solvents may damage hearing. Results suggest the need for expanding hearing conservation programs to consider combinations of exposures to metals, solvents, and noise.
Decomposition of transcriptional signals from tumours using independent component analysis
Creators: name: Nazarov, Petr V.
name: Gobin, Matthieu
name: Zinovyev, Andrei
name: Dyck, Eric Van
name: Vallar, Laurent
Publisher: name: F1000Research
Year: 2017

description: Tumour samples have complex cellular composition and show a high level of heterogeneity. The presence of stromal and immune cells, as well as polyclonality of cancer cells, limits interpretability of collected high-throughput data. Here we investigated and applied Independent Component Analysis (ICA) to decompose mixed signals in RNAseq data.

First, we validated ICA approach in silico. Five cancers presented at TCGA repositories were selected: two brain cancers (GMB, LGG), melanoma (SKCM), lung squamous cell carcinoma (LUSC) and breast cancer (BRAC). Synthetic mixtures of their gene expression profiles were generated and then decomposed by ICA.  We showed that, in order to obtain a robust separation, special attention to data transformation was needed and multiple runs of ICA were required.

Next, we performed an in-depth analysis of 169 GBM and 473 SKCM samples. Gene signatures specific to each independent component were determined and associated to gene ontology categories. We identified components originated from different cell types and biological processes – some common and some specific to each tumour. Strong immune signals, neural tissue development and cell proliferation components were seen in both cancers, whereas components linked to melanin and keratin production – only in SKCM. Involvement of each component in samples was linked to clinical factors by ANOVA. We found a strong statistical connection between some of the components and methylation status. In GBM, many components were linked to Verhaak’s tumour subclasses.

Therefore, we conclude that ICA can detect cell subpopulations in bulk tissues, and help identifying gene signatures with diagnostic potential.
Glycated Hemoglobin and Risk of Arterial Stiffness in a Chinese Han Population: A Longitudinal Study
Creators: name: Han, Ze
name: Kang, Xiaoping
name: Zhang, Jie
name: Wang, Jinqi
name: Liu, Yue
name: Liu, Jia
name: Wu, Zhiyuan
name: Li, Xia
name: Zhao, Xiaoyu
name: Guo, Xiuhua
name: Chen, Shuo
name: Tao, Lixin
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 320299
subject: Clinical sciences not elsewhere classified

description: Background and Aims: Glycated hemoglobin (HbA1c) associates with the risk of arterial stiffness, and such association can be found between fasting blood glucose (FBG), postprandial blood glucose (PBG), triglyceride-glucose index (TyG index), and arterial stiffness. However, the results were inconsistent, longitudinal studies were sparse, and comparison of these glycemic parameters was less conducted. We aimed to explore the longitudinal relationship between HbA1c and arterial stiffness and compare the effect of the parameters. Methods: Data were collected from 2011 to 2019 in Beijing Health Management Cohort (BHMC) study. Cox proportional hazard models were fitted to investigate the association between the parameters and arterial stiffness. A generalized estimation equation (GEE) analysis was conducted to investigate the effect of repeated measurements of glycemic parameters. A receiver operating characteristic (ROC) analysis was performed to compare the predictive value of glycemic parameters for arterial stiffness. Results: Among 3,048 subjects, 591 were diagnosed as arterial stiffness during the follow-up. The adjusted hazard ratio (HR) [95% confidence interval (CI)] for arterial stiffness of the highest quartile group of HbA1c was 1.63 (1.22-2.18), which was higher than those of FBG, PBG, and TyG index. The nonlinear association of arterial stiffness with HbA1c and PBG was proved. The robust results of the sensitivity analysis were obtained. Conclusions: HbA1c is an important risk factor of arterial stiffness compared with PBG, FBG, and TyG index, and has a strong predictive ability for arterial stiffness among non-diabetics and the general population.
GEELHOED_Supplementary_Information_to_Manuscript_1 – Supplemental material for Performance of the Prototype NovioSense Noninvasive Biosensor for Tear Glucose in Type 1 Diabetes
Creators: name: Geelhoed-Duijvestijn, Petronella
name: Dovile Vegelyte
name: Kownacka, Alicja
name: Anton, Nicoleta
name: Joosse, Maurits
name: Wilson, Christopher
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: Medicine
subject: 111199 Nutrition and Dietetics not elsewhere classified

description: Supplemental material, GEELHOED_Supplementary_Information_to_Manuscript_1 for Performance of the Prototype NovioSense Noninvasive Biosensor for Tear Glucose in Type 1 Diabetes by Petronella Geelhoed-Duijvestijn, Dovile Vegelyte, Alicja Kownacka, Nicoleta Anton, Maurits Joosse and Christopher Wilson in Journal of Diabetes Science and Technology
Knowledge, attitudes, and practice of general practitioners toward community detection and management of mild cognitive impairment: a cross-sectional study in Shanghai, China
Creators: name: Lu, Yuan
name: Liu, Chaojie
name: Fawkes, Sally
name: Wang, Z
name: Yu, D
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 420699
subject: Public health not elsewhere classified

description: Background: General practitioners (GPs) are in a unique position for community detection and management of mild cognitive impairment (MCI). However, adequate knowledge, attitudes, and practice (KAP) are prerequisites for fulfilling such a role. This study aims to assess the MCI-related KAP of GPs in Shanghai, China. Methods: An online survey was conducted on 1253 GPs who were recruited from 56 community health centres (CHCs) in Shanghai between April and May 2021. Knowledge (8 items), attitudes (13 items), and practice (11 items) were assessed using a scale endorsed by a panel of multidisciplinary experts. An average summed score was calculated and transformed into a score ranging from 0 to 100 for knowledge, attitudes, and practice, respectively. Adjusted odds ratios (AORs) were calculated for potential predictors of higher levels of KAP scores (with mean value as a cutoff point) through logistic modelling. The mediating role of attitudes on the association between knowledge and practice was tested using the PROCESS model 4 macro with 5000 bootstrap samples through linear regression modelling. Results: A total of 1253 GPs completed the questionnaire, with an average score of 54.51 ± 18.18, 57.31 ± 7.43, and 50.05 ± 19.80 for knowledge, attitudes, and practice, respectively. More than 12% of respondents scored zero in knowledge, 28.4% tended not to consider MCI as a disease, and 19.1% completely rejected MCI screening. Higher levels of knowledge were associated with more favourable attitudes toward community management of MCI (AOR = 1.974, p < 0.001). Higher compliance with practice guidelines was associated with both higher levels of knowledge (AOR = 1.426, p < 0.01) and more favourable attitudes (AOR = 2.095, p < 0.001). The association between knowledge and practice was partially mediated by attitudes (p < 0.001). Training was associated with higher levels of knowledge (AOR = 1.553, p < 0.01), while past experience in MCI management was associated with more favourable attitudes (AOR = 1.582, p < 0.05) and higher compliance with practice guidelines (AOR = 3.034, p < 0.001). MCI screening qualification was associated with higher compliance with practice guidelines (AOR = 2.162, p < 0.05), but less favourable attitudes (AOR = 0.452, p < 0.05). Conclusion: The MCI knowledge of GPs in Shanghai is low, and is associated with less favourable attitudes toward MCI management and low compliance with practice guidelines. Attitudes mediate the association between knowledge and practice. Training is a significant predictor of knowledge. Further studies are needed to better understand how the attitudes of GPs in Shanghai are shaped by the environments in which they live and work.
Literature review of occurrence, effectiveness, safety, and hospitalization burden of blood transfusion in the management of warm autoimmune hemolytic anemia
Creators: name: Barros, Melca
name: Leon, Ann
name: Crivera, Concetta
name: Cusson, Elissa
name: Kodjamanova, Petya
name: Bagnall, Robert
name: Panch, Sandhya R.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Cases of warm autoimmune hemolytic anemia (wAIHA) often present with life-threatening levels of hemoglobin requiring red blood cell (RBC) transfusion support. This literature review assessed the occurrence, safety, effectiveness, and hospitalization burden of RBC transfusions in the management of patients with wAIHA. Electronic databases (Embase, MEDLINE) were searched from inception to December 2021 along with additional searches conducted up to March 2024. Of the 1478 articles screened, 17 observational studies and reviews were included. These studies demonstrated the use of 1−50 red blood cell transfusions to reach clinically acceptable hemoglobin levels in patients with wAIHA. In general, pre-transfusion hemoglobin levels were 6 g/dL and increased by an average 1.2 g/dL following a transfusion. Approximately 50% of patients with primary or secondary wAIHA suffered relapses. No data was available to distinguish between RBC transfusions used at initial presentation versus during relapse. Five studies found no increase in hemolysis or serious adverse reactions following transfusions and two studies reported mild transfusion-related adverse effects. Limited data was available regarding the hospitalization burden of RBC transfusion. Patients with wAIHA requiring transfusions had a median hospital stay from 15 to 17 days, which is considerably higher than all causes hospitalization of 4.5 days for 2023 U.S. In patients with wAIHA, data supports wide variability in occurrence, but relative safety and effectiveness of RBC transfusions as supportive therapy. Additional studies are needed to assess the occurrence, safety, and hospitalization burden of RBC transfusions relative to other therapies in chronic relapsing wAIHA.
Additional file 1 of Year-round tick exposure of dogs and cats in Germany and Austria: results from a tick collection study
Creators: name: Probst, Julia
name: Springer, Andrea
name: Strube, Christina
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Table S1. Infestation rates with the most frequently collected tick species among tick-infested dogs and cats in the different German and Austrian federal states (number of infested hosts/% of all examined).
Mathematical_Appendix_21_7_2020 – Supplemental material for Cancer prevalence by phase of care: an indicator for assessing health service needs
Creators: name: Gigli, Anna
name: Francisci, Silvia
name: Guzzinati, Stefano
name: Hall, Aaron
name: Hachey, Mark
name: Scoppa, Steve
name: Mariotto, Angela
Publisher: name: SAGE Journals
Year: 2020
Subjects: Medicine

description: Supplemental material, Mathematical_Appendix_21_7_2020 for Cancer prevalence by phase of care: an indicator for assessing health service needs by Anna Gigli, Silvia Francisci, Stefano Guzzinati, Aaron Hall, Mark Hachey, Steve Scoppa and Angela Mariotto in Tumori Journal
Why are we not boycotting Academia.edu ? My participation
Creators: name: Aventurier, Pascal
Publisher: name: unknown
Year: 2017

description: Aventurier, P. (2015). Why are we not boycotting Academia.edu ? My participation. Presented at Why are we not boycotting Academia.edu ?, Coventry, GBR (2015-12-08).
http://prodinra.inra.fr/record/339157
Skin in the Climate Game
Creators: name: Julian, June
Publisher: name: unknown
Year: 2016
Subjects: subject: Mohs surgery
subject: Painting
subject: Wildfires
subject: Desert ecology
subject: Art
subject: Human figure in art
subject: New York (State)--New York
subject: Skin--Cancer
subject: Climatic changes

description: A personal account of the author's experience with skin cancer and its relationship to climate change.
It includes 6 original acrylic paintings in her "Here Not There" series.
The paintings show solitary pale nude figures reclining in an expanse of scorching desert with a backdrop of fiery skies, distant mesas and mountains. The colors are hot, super saturated reds, oranges and yellows. Something is burning. Are we all burning?
Additional file 1 of The usage of data in NHS primary care commissioning: a realist review
Creators: name: Jager, Alexandra
name: Wong, Geoff
name: Papoutsi, Chrysanthi
name: Roberts, Nia
Publisher: name: figshare
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1. Detailed overview of 5-step review process.
sj-pdf-1-jhs-10.1177_1753193420965390 - Supplemental material for Non-operative treatment versus suture refixation of the nail plate in paediatric fingernail avulsion injuries
Creators: name: Seiler, Michelle
name: Gerstenberg, Anja
name: Kalisch, Markus
name: Uchenna Kennedy
name: Scheer, Helene S.
name: Weber, Daniel M.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-jhs-10.1177_1753193420965390 for Non-operative treatment versus suture refixation of the nail plate in paediatric fingernail avulsion injuries by Michelle Seiler, Anja Gerstenberg, Markus Kalisch, Uchenna Kennedy, Helene S. Scheer and Daniel M. Weber in Journal of Hand Surgery (European Volume)
Skin in the Climate Game
Creators: name: Julian, June
Publisher: name: Humanities Commons
Year: 2016
Subjects: subject: Climatic changes
subject: Wildfires
subject: Mohs surgery
subject: Skin--Cancer
subject: Painting
subject: Art
subject: Human figure in art
subject: Desert ecology
subject: New York (State)--New York

description: A personal account of the author's experience with skin cancer and its relationship to climate change. It includes 6 original acrylic paintings in her "Here Not There" series. The paintings show solitary pale nude figures reclining in an expanse of scorching desert with a backdrop of fiery skies, distant mesas and mountains.  The colors are hot, super saturated reds, oranges and yellows. Something is burning. Are we all burning?
The costs of treating bleeding episodes in patients with immune thrombocytopaenia in the United Kingdom
Creators: name: McDonald, Vickie
name: Guterres, Sebastian
name: James, Samuel
name: Zakrzewski, Maja
name: Pochopień, Michał
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Immune thrombocytopaenia (ITP) is a rare autoimmune disorder characterized by low platelet count and increased risk of bleeding. This study aimed to be the first publication to characterize the economic burden of bleeding events in patients with ITP in the UK. We performed a microcosting analysis to estimate the costs associated with bleeding events in patients with ITP. Healthcare resources utilized in the management of bleeds of different severity were costed using well-established UK cost sources. The results were validated through semi-structured interviews with clinical experts. The severity of bleeding events was classified into four categories, ranging from bleeding managed at home, through mild bleeding managed in the outpatient or day case setting, to serious and life-threatening bleeding events requiring inpatient admission. Total medical costs per event ranged from £2,930 for managing a mild bleeding event, through £16,711 for a serious bleeding event to £32,461 for a life-threatening event. The major cost driver for mild and serious events were intravenous immunoglobulin (IVIg) costs, amounting to £1,614 and £8,071 for the two severity categories, respectively. For life-threatening events, the costs of intensive care unit stay (£9,089) exceeded those of IVIg (£8,071). Real-world costs of managing bleeding in patients with ITP in the UK are substantial and greater than costs set only based on the UK NHS Tariff. Mitigating the risk of bleeding in patients with ITP is likely to yield not only clinical advantages for patients but also offer substantial cost savings to the health system.
Infrastructure for Open Access: Mechanics, Economics, Politics
Creators: name: Gearhart, Andrew
name: Mattson, Mark
name: O'Sullivan, James
name: Pickle, Sarah
Publisher: name: Rowman & Littlefield
Year: 2016
Subjects: subject: Digital humanities

description: Using the Pennsylvania State University Libraries as a case study, this essay explores the development of a library-based open access publishing program, and illustrates how open access library publishing can facilitate open access models by providing additional infrastructure for the dissemination of scholarly content.
ALKBH3-mediated m1A demethylation promotes the malignant progression of acute myeloid leukemia by regulating ferroptosis through the upregulation of ATF4 expression
Creators: name: Liu, Xin
name: Pan, Xinghua
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: To investigate the role of ALKBH3 in acute myeloid leukemia (AML), we constructed an animal model of xenotransplantation of AML. Our study demonstrated that ALKBH3-mediated m1A demethylation inhibits ferroptosis in KG-1 cells by increasing ATF4 expression, thus promoting the development of AML. These findings suggest that reducing ALKBH3 expression may be a potential strategy to mitigate AML progression. Background: Acute myeloid leukemia (AML) is characterized by the unrestrained proliferation of myeloid cells. Studies have shown that ALKBH3 is upregulated in most tumors, but the role of ALKBH3 in AML remains unclear. Methods: In this study, we investigated the function of ALKBH3 in AML cells (KG-1) by immunofluorescence, ELISA, flow cytometry, HE staining, and Western blotting. Results: Our results revealed that ALKBH3 is upregulated in AML and that the downregulation of ALKBH3 inhibited KG-1 cell proliferation and promoted cell apoptosis; at the same time, ALKBH3 upregulated ATF4 expression through m1A demethylation, and the knockdown of ATF4 resulted in increased ferrous iron content; TFR1, ACSL4, and PTGS2 expression; and ROS and MDA levels, whereas SOD and GSH levels and the expression levels of ATF4, SLC7A11, GPX4, and FTH1 decreased in KG-1 cells, thereby promoting ferroptosis. Mechanistically, ALKBH3-mediated m1A demethylation suppressed ferroptosis in KG-1 cells by increasing ATF4 expression, thereby promoting the development of AML. Conclusions: Our study indicated that reducing the expression of ALKBH3 might be a potential target for improving AML symptoms.
Glycyrrhiza glabra and Saussurea costus extracts mitigate arsenic-induced nephrotoxicity via orchestrating Nrf2/HO-1 and NF-kB crosstalk and repressing the expression of HSPs genes, and apoptosis in broiler chickens
Creators: name: Elazab, Sara T.
name: Safhi, Fatmah A.
name: Al-Rasheed, Mohammed
name: Kishawy, Asmaa T.Y.
name: Ibrahim, Doaa
name: EL-Emam, Huda A.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy

description: This research aimed to evaluate the role of Glycyrrhiza glabra (GGE) and Saussurea costus (Costus) extracts in alleviating arsenic (As2O3)-evoked nephrotoxicity in chickens. Seven groups (36 chicks/group) were treated daily for 42 days as follows: control group; GGE group, obtained GGE (500 mg/kg feed); Costus group was given Costus orally (300 mg/kg bodyweight); As group, received As2O3 (30 mg/kg diet); As + GGE; As + Costus; As + GGE + Costus. The administration of GGE and/or Costus in As-intoxicated birds significantly decreased (p < 0.001) creatinine level relative to As group. Additionally, both extracts markedly reduced (p < 0.001) the renal malondialdehyde content and enhanced the antioxidant enzymes performance, which function via Nrf2/HO-1 signaling. Moreover, They downregulated the renal inflammatory cascade by suppressing the expression of TNF-α and NF-κB genes compared to As group. Furthermore, a significant decline in the levels of HSPs mRNA was recorded following treatment with GGE and/or Costus. Conclusively, GGE and Costus can be accounted as prospective antidotes in controlling As poisoning.
Additional file 5 of The usage of data in NHS primary care commissioning: a realist review
Creators: name: Jager, Alexandra
name: Wong, Geoff
name: Papoutsi, Chrysanthi
name: Roberts, Nia
Publisher: name: figshare
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 5. Final programme theory.
3D Single Molecule Super-Resolution Microscopy of Whole Nuclear Lamina
Creators: name: Rozario, Ashley
name: Morey, A
name: Elliott, C
name: Russ, B
name: Whelan, Donna
name: Turner, SJ
name: Bell, TDM
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 519999
subject: Other physical sciences not elsewhere classified

description: Single molecule (SM) super-resolution microscopies bypass the diffraction limit of conventional optical techniques and provide excellent spatial resolutions in the tens of nanometers without overly complex microscope hardware. SM imaging using optical astigmatism is an efficient strategy for visualizing subcellular features in 3D with a z-range of up to ∼1 µm per acquisition. This approach however, places high demands on fluorophore brightness and photoswitching resilience meaning that imaging entire cell volumes in 3D using SM super-resolution remains challenging. Here we employ SM astigmatism together with multiplane acquisition to visualize the whole nuclear lamina of COS-7 and T cells in 3D. Nuclear lamina provides structural support to the nuclear envelope and participates in vital nuclear functions including internuclear transport, chromatin organization and gene regulation. Its position at the periphery of the nucleus provides a visible reference of the nuclear boundary and can be used to quantify the spatial distribution of intranuclear components such as histone modifications and transcription factors. We found Alexa Fluor 647, a popular photoswitchable fluorophore, remained viable for over an hour of continuous high laser power exposure, and provided sufficient brightness detectable up to 8 µm deep into a cell, allowing us to capture the entire nuclear lamina in 3D. Our approach provides sufficient super-resolution detail of nuclear lamina morphology to enable quantification of overall nuclear dimensions and local membrane features.
'The landscape is coded': Visual Culture and the Alternative Worlds of J.G. Ballard's Early Fiction
Creators: name: Daley, Christopher
Publisher: name: Peter Lang
Year: 2014
Subjects: subject: Literature and science
subject: Art--History

description: This chapter focuses on three early narratives by J.G. Ballard and consider how Ballard's near-future landscapes emerge from a collision of various artistic and literary forces. It argues that by fusing perspectives in visual art with science fictional motifs, Ballard's early narratives produced socio-political messages which challenged literary orthodoxies during the late 1950s and early 1960s.
A deep dive into the venom apparatus of the freshwater stingray: an integrated investigation of biochemical, morphological, and pathophysiological parameters
Creators: name: Castanhola-Dias, Lucas
name: Lameiras, Juliana
name: Coelho, Guilherme
name: Zychar, Bianca Cestari
name: Dale, Camila
name: da Silva Oliveira, Victória Regina
name: Cury, Diego Pulzatto
name: dos Prazeres Silva, Karoline
name: Pimenta, Daniel Carvalho
name: Morales-Gamba, Ruben Dario
name: Falla, Monica Viviana Abreu
name: Costa, Oscar
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences

description: The stinger of stingrays, located along the tail’s mid-dorsal line, contains venom and mucus glands. This study aims to analyze the secretions of the stinger and dorsal mucus (DM) in Potamotrygon wallacei and examine their epithelium. Extracts from DM, stinger, and dorsal epithelium (DE) were analyzed via SDS-PAGE and microscopy. The effects of these extracts on edema and pain were tested in mice, showing that the stinger and DE shared similar protein compositions. Venom cells in the stinger play a major role in venom production. Both stinger and mucus extracts induced pain, inflammation, and necrosis in mice, highlighting complex interactions.
Additional file 4 of The usage of data in NHS primary care commissioning: a realist review
Creators: name: Jager, Alexandra
name: Wong, Geoff
name: Papoutsi, Chrysanthi
name: Roberts, Nia
Publisher: name: figshare
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 4. Table of included studies.
PUS_Employer_SupportingInformation1_Instrument – Supplemental material for Lay beliefs about scientists’ relations with their employers
Creators: name: Johnson, Branden B.
name: Dieckmann, Nathan F.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: Science Policy

description: Supplemental material, PUS_Employer_SupportingInformation1_Instrument for Lay beliefs about scientists’ relations with their employers by Branden B. Johnson and Nathan F. Dieckmann in Public Understanding of Science
Supplemental Material, Appendix_A._Prisma_Flow_Chart - A Scoping Review of the Trauma Recovery and Empowerment Model (TREM)
Creators: name: Masin-Moyer, Melanie
name: Kim, Jessica Cho
name: Engstrom, Malitta
name: Solomon, Phyllis
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, Appendix_A._Prisma_Flow_Chart for A Scoping Review of the Trauma Recovery and Empowerment Model (TREM) by Melanie Masin-Moyer, Jessica Cho Kim, Malitta Engstrom and Phyllis Solomon in Trauma, Violence, & Abuse
Dunatchik_Online_Appendix – Supplemental material for Reducing mommy penalties with daddy quotas
Creators: name: Dunatchik, Allison
name: Özcan, Berkay
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 160512 Social Policy

description: Supplemental material, Dunatchik_Online_Appendix for Reducing mommy penalties with daddy quotas by Allison Dunatchik and Berkay Özcan in Journal of European Social Policy
Additional file 2 of The usage of data in NHS primary care commissioning: a realist review
Creators: name: Jager, Alexandra
name: Wong, Geoff
name: Papoutsi, Chrysanthi
name: Roberts, Nia
Publisher: name: figshare
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 2. Emerging CMO configurations.
TME_in_High_Grade_Ovarian_Cancer_Supplementary_Material – Supplemental material for Characterization of immunoreactivity with whole-slide imaging and digital analysis in high-grade serous ovarian cancer
Creators: name: Jäntti, Tiina
name: Luhtala, Satu
name: Mäenpää, Johanna
name: Staff, Synnöve
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: Cell Biology

description: Supplemental material, TME_in_High_Grade_Ovarian_Cancer_Supplementary_Material for Characterization of immunoreactivity with whole-slide imaging and digital analysis in high-grade serous ovarian cancer by Tiina Jäntti, Satu Luhtala, Johanna Mäenpää and Synnöve Staff in Tumor Biology
HUMN 2439: Radical Political Thought (2017-01)
Creators: name: Gifford, James
Publisher: name: unknown
Year: 2017

description: This course explores major currents of political radicalism both within and outside of the dominant western political tradition. Topics considered may include antidemocratic radicalism, democratic radicalism, Marxian radicalism, radical feminism, radical individualism, and post-colonial radicalism. Readings will include selections from Kant, Wollstonecraft, Marx, Luxemburg, Read, Fanon, p'Bitek, Woodcock, and Wolff. Students will be invited to consider seriously both justifications and criticisms of democracy, liberal individualism, capitalism, patriarchy, and colonialism, and draw their own conclusions. Attention will be paid to historical context, although no prior study of history or the history of political thought is required.
Additional file 3 of The usage of data in NHS primary care commissioning: a realist review
Creators: name: Jager, Alexandra
name: Wong, Geoff
name: Papoutsi, Chrysanthi
name: Roberts, Nia
Publisher: name: figshare
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 3. Literature research.
sj-pdf-1-pul-10.1177_2045894020961713 - Supplemental material for Evaluation of code-based algorithms to identify pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients in large administrative databases
Creators: name: Sprecher, Viviane P.
name: Eva-Maria Didden
name: Swerdel, Joel N.
name: Muller, Audrey
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Cardiology
subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-pul-10.1177_2045894020961713 for Evaluation of code-based algorithms to identify pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients in large administrative databases by Viviane P. Sprecher, Eva-Maria Didden, Joel N. Swerdel and Audrey Muller in Pulmonary Circulation
REMOVAL OF IRON, COPPER, COLIFORM BACTERIA AND HARDNESS FROM COOLING TOWER WATER BY DISSOLVED AIR-OZONE FLOTATION
Creators: name: Pankivskyi, Yuriy I.
name: Wang, Lawrence K
name: Wang, Mu-Hao Sung
Publisher: name: Lenox Institute Press, MA, USA.
Year: 2022
Subjects: subject: Iron
subject: Enterobacteriaceae
subject: Water--Purification--Dissolved air flotation--Testing
subject: Hardness
subject: Copper
subject: Water treatment plants--Environmental aspects
subject: Cooling towers
subject: Ozonization
subject: Flotation
subject: Water--Purification--Filtration

description: An ozone-assisted physical-chemical treatment process involving the use of chemical coagulation-precipitation, clarification (either sedimentation or flotation) and filtration for cooling tower raw make-up water treatment, side-stream recirculating water treatment, or blowndown water treatment was investigated by the Lenox Institute of Water Technology (LIWT) using bench-scale laboratory tests, continuous pilot plant demonstration, and full-scale cooling tower operation. Only the preliminary laboratory data are introduced at this stage. The results show that 95 % of iron ions, 67.8 % of copper ions , 100 % of total coliform bacteria, and over 98 % of total hardness can be removed by the ozone-assisted dissolved air-ozone flotation and filtration (DAOFF) process system. The DAOFF system may be adopted for (a) production of cooling tower make-up water using raw reservoir/stream water or raw groundwater water as the source water; (b) treatment of cooling tower side-stream recirculation water for scale removal, new scale prevention, corrosion, bacteria disinfection, algae control and water purification; or (c) treatment of cooling tower blowdown water for final discharge to a deep well (without groundwater contamination), an ocean, or a receiving water (without thermal pollution nor excessive TDS). Ozone kills all bacteria slimes which commonly bind the scale on the metal surface, and keeps the hardness in suspension, so the suspended hardness will not form scale, and may be effectively removed by filtration.
RUNX1::MECOM rearrangement in myeloid neoplasm post cytotoxic therapy following sarcoma treatment: a case presentation and review of the literature
Creators: name: Sandnes, Miriam
name: Sefland, Øystein
name: Ktoridou-Valen, Irini
name: Forthun, Rakel Brendsdal
name: Gjelberg, Hilde Kollsete
name: Hamnvik, Lars Henrik Dahl
name: Reikvam, Håkon
name: Tvedt, Tor Henrik Andersson
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Myeloid neoplasms occurring after cytotoxic therapy (MN-pCT), previously termed therapy-related myelodysplastic neoplasia (MDS) or therapy-related acute myelogenous leukemia (AML), pose significant treatment challenges due to high resistance, poor chemotherapy tolerance, and relapse. We present a 73-year-old woman with therapy-related AML following treatment for myxofibrosarcoma, characterized by the rare RUNX1::MECOM fusion resulting from a t(3;21)(q26;q22) chromosomal translocation. We also review the current literature regarding cases of this rare translocation. The patient, previously treated with chemotherapy and radiotherapy for sarcoma, was diagnosed with pancytopenia and hypoplastic bone marrow with increased blasts. Cytogenetic analysis confirmed RUNX1::MECOM fusion. Furthermore, we discuss the molecular mechanisms underlying MECOM rearrangements, specifically the role of the EVI1 oncogene. AML associated with MECOM rearrangements is associated with poor prognosis and resistance to conventional therapies. While allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the only potential curative treatment, the high relapse rate limits its efficacy. Recent advancements in understanding the molecular drivers of MECOM-related AML suggest potential therapeutic strategies, including hypomethylating agents and novel combinations such as lenalidomide. this case and literature review emphasizes the importance of long-term monitoring of cancer survivors treated with cytotoxic therapies, as well as awareness of rare translocations in MN-pCT.
A Survey of the Nurse Rostering Solution Methodologies: The State-of-the-Art and Emerging Trends
Creators: name: Ngoo, Chong Man
name: Goh, Say Leng
name: Sze, San Nah
name: Sabar, Nasser
name: Abdullah, Salwani
name: Kendall, Graham
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 490404
subject: Combinatorics and discrete mathematics (excl. physical combinatorics)

description: No description supplied
sj-pdf-1-wso-10.1177_1747493020971166 - Supplemental material for Time-dependent, dynamic prediction of fatty acid-binding protein 4, Galectin-3, and soluble ST2 measurement with poor outcome after acute stroke
Creators: name: Hansen, Christina
name: Sastre, Cristina
name: Wolcott, Zoe
name: Bevers, Matthew B
name: W Taylor Kimberly
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Cardiology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-wso-10.1177_1747493020971166 for Time-dependent, dynamic prediction of fatty acid-binding protein 4, Galectin-3, and soluble ST2 measurement with poor outcome after acute stroke by Christina Hansen, Cristina Sastre, Zoe Wolcott, Matthew B Bevers and W Taylor Kimberly in International Journal of Stroke
Additional file 1 of Implementation strategies to scale up self-administered depot medroxyprogesterone acetate subcutaneous injectable contraception: a scoping review
Creators: name: Aderoba, Adeniyi Kolade
name: Steyn, Petrus Schoken
name: Kiarie, James Njogu
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Pharmacology
Science Policy

description: Additional file 1: Supplementary material. Search strategies.
Supplemental Material, Appendices - Barriers, Facilitators and Recommended Strategies for Implementing a Home-Based Palliative Care Intervention in Kolkata, India
Creators: name: Suparna Qanungo
name: Calvo-Schimmel, Alejandra
name: McGue, Shannon
name: Singh, Pooja
name: Roy, Rakesh
name: Bhattacharjee, Gautam
name: Nibedita Panda
name: Gaurav Kumar
name: Chowdhury, Rekha
name: Cartmell, Kathleen B.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences
subject: 111702 Aged Health Care

description: Supplemental Material, Appendices for Barriers, Facilitators and Recommended Strategies for Implementing a Home-Based Palliative Care Intervention in Kolkata, India by Suparna Qanungo, Alejandra Calvo-Schimmel, Shannon McGue, Pooja Singh, Rakesh Roy, Gautam Bhattacharjee, Nibedita Panda, Gaurav Kumar, Rekha Chowdhury and Kathleen B. Cartmell in American Journal of Hospice and Palliative Medicine®
Enriching vs. corrosive values in academia: which do our current metrics reinforce?
Creators: name: Konkiel, Stacy
Publisher: name: unknown
Year: 2016
Subjects: subject: Education, Higher
subject: Philosophy
subject: FOS: Philosophy, ethics and religion

description: As part of the TriangleSCI HuMetrics working group, I spent the better part of this afternoon brainstorming and debating academic values, products, processes, and metrics in an attempt to lay a foundation for this week's attempt at articulating "humane metrics" for the humanities.

As our discussion winded down, it occurred to the team that we were working with an important assumption re: values: we had spent the day identifying only those "enriching" values that we wanted to encourage (collaboration, generosity, inclusivity, quality, etc), rather than examining the current set of values we wished to discourage, those that in many ways are "corroding" academia (competition, bureaucracy, exclusivity, etc)...
Supplementary Material 1 - Supplemental material for A Unified Total Synthesis of Isocyclocapitelline and Cyclocapitelline
Creators: name: Marepally Srilatha
name: Vallabhareddy Satteyyanaidu
name: Chepyala Krishna Reddy
name: Venkata Subba Reddy Reddy Basireddy
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, Supplementary Material 1, for A Unified Total Synthesis of Isocyclocapitelline and Cyclocapitelline by Marepally Srilatha, Vallabhareddy Satteyyanaidu, Chepyala Krishna Reddy and Venkata Subba Reddy Reddy Basireddy in Natural Product Communications
A rare −α27.6 deletion compounded with the hemoglobin constant spring mutation identified in a Chinese couple
Creators: name: Li, Wei
name: Guo, Zhao-Yi
name: Xiu, Zi-Han
name: Long, Min
name: Xiao, Yan
name: Liu, Li-Yi
name: Chen, Yu-Chen
name: Zeng, Si-Fan
name: Zhang, Jing
name: Zhang, Min
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Thalassemia is a common hemoglobin disorder caused by genetic defects in a single autosomal gene. Based on the deficient globin strand, it can be classified as α-thalassemia or β-thalassemia. The 27.6 kb deletion on α-globin related gene cluster (−α27.6) is a rare α-thalassemia variant discovered in 2011, which could affect the detection of common α-thalassemia variants and cause misdiagnosis. An α-thalassemia variant carrying a Chinese couple was reported in this study. The wife was diagnosed at another hospital as αCSα/αCSα but did not manifest corresponding symptoms. After further examinations and in-depth analyses of the results, the genotype of the wife was finally confirmed to be −α27.6/αCSα. Meanwhile, the genotype of the husband was diagnosed as αCSα/αα. The couple requested prenatal diagnosis in the worry of α-thalassemia caused by αCSα/αCSα. Genetic tests on the amniotic fluid reported a mild thalassemia-related genotype of αCSα/αα, on which our suggestion of continuing pregnancy was based. The −α27.6/αCSα case and related manifestations were first reported here expanding the gene spectrum of thalassemia. Such genotype can be misdiagnosed as αCSα/αCSα causing inaccurate estimations of thalassemia risk. To avoid these misdiagnoses, genetic tests for deletions in the related regions were advised when inconsistencies between the genotype and the phenotype were discovered.
sj-pdf-1-jrs-10.1177_0141076820956799 - Supplemental material for Reducing bias and improving transparency in medical research: a critical overview of the problems, progress and suggested next steps
Creators: name: Bradley, Stephen H
name: DeVito, Nicholas J
name: Lloyd, Kelly E
name: Richards, Georgia C
name: Rombey, Tanja
name: Wayant, Cole
name: Gill, Peter J
Publisher: name: SAGE Journals
Year: 2020
Subjects: Medicine

description: Supplemental material, sj-pdf-1-jrs-10.1177_0141076820956799 for Reducing bias and improving transparency in medical research: a critical overview of the problems, progress and suggested next steps by Stephen H Bradley, Nicholas J DeVito, Kelly E Lloyd, Georgia C Richards, Tanja Rombey, Cole Wayant and Peter J Gill in Journal of the Royal Society of Medicine
The Peripatetic Method: Walking with Woodbridge, Thinking with Aristotle
Creators: name: Long, Christopher
Publisher: name: Bloomsbury Academic
Year: 2014
Subjects: subject: Philosophy
subject: FOS: Philosophy, ethics and religion

description: Drawing on the poetry of Wallace Stevens and the remarkable series of lectures Frederick J. E. Woodbridge gave at Union College in 1930 entitled, simply, "The Philosophy of Aristotle," but published under the title Aristotle's Vision of Nature, this paper identifies the path of Aristotle's thinking, its method, as a "peripatetic legomenology." It is a legomenology because it attends carefully to the manner in which things are said (ta legomena), and peripatetic because it follows the things said as a way into the nature of things.