cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MOESM2 of Immunoglobulin somatic hypermutation has clinical impact in DLBCL and potential implications for immune checkpoint blockade and neoantigen-based immunotherapies
Creators: name: Xu-Monette, Zijun
name: Li, Jianyong
name: Xia, Yi
name: Crossley, Beryl
name: Bremel, Robert
name: Miao, Yi
name: Xiao, Min
name: Snyder, Thomas
name: Manyam, Ganiraju
name: Tan, Xiaohong
name: Zhang, Hongwei
name: Visco, Carlo
name: Tzankov, Alexandar
name: Dybkaer, Karen
name: Bhagat, Govind
name: Tam, Wayne
name: You, Hua
name: Hsi, Eric
name: Krieken, J.
name: Huh, Jooryung
name: Ponzoni, Maurilio
name: Ferreri, AndrĂŠs
name: MĂ¸ller, Michael
name: Piris, Miguel
name: Winter, Jane
name: Medeiros, Jeffrey
name: Xu, Bing
name: Li, Yong
name: Kirsch, Ilan
name: Young, Ken
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Table S1. Clinical features of 378 patients in the training and validation cohort whose DLBCL biopsies were sequenced and 290 patients whose sequencing results showed sufficient sequence reads. Table S2. Comparisons of clinicopathologic and molecular characteristics between patients with germinal-center B-cellâ like (GCB) DLBCL with a low or high degree of somatic hypermutation (SHM) in immunoglobulin variable region genes. Table S3. Comparisons of clinicopathologic and molecular characteristics between patients with activated B-cell-like (ABC) subtype of DLBCL with a low or high degree of SHM in immunoglobulin variable region genes. Table S4. Significant prognostic effects of immunoglobulin molecular characteristics in DLBCL patients treated with R-CHOP by multivariate survival analysis. Table S5. Clinicopathologic and molecular characteristics of patients with DLBCL with a short or long immunoglobulin heavy/light chain CDR3 length. Table S6. Clinicopathologic and molecular characteristics of patients with DLBCL with ongoing SHM in immunoglobulin variable region genes. Table S7. Gene signatures associated with SHM in immunoglobulin sequences of DLBCL samples. Table S8. Multiple testing corrections for prognostic effects found in the overall cohort of DLBCL treated with R-CHOP by the Benjamini-Hochberg method with a false discovery rate of 0.10
title: A STUDY INTO THE DRIVING FORCES BEHIND STRATEGIC DECISION-MAKING IN THE ONLINE GAMBLING INDUSTRY
Creators: name: Gottmann, OF
Publisher: name: University of Liverpool Repository
Year: 2018

description: This thesis explores decision-making at the senior management level in the online gambling industry. The aim being to understand corporate decision making during key strategic events for companies within this industry, to discover the thinking around these decisions, the assumptions made and their influences, and to make recommendations for practice. The theoretical context is that of an increasing complex industry and the inability of the decisions-makers to adapt. The main literary strands drawn upon are that of heuristic-based reasoning and bias, intuition, tenure and ethics. The analysis focuses upon three companies within the online gambling industry and strategic decisions made by each. My own experiences in this study are also prevalent.
Date-Sublethal effects of COS on Rhopalosiphum padi
Creators: name: Xinan, Li
Publisher: name: figshare
Year: 2023
Subjects: Population ecology

description: A sublethal concentration of chitosan oligosaccharide suppresses the population growth of the wheat aphid, Rhopalosiphum padi (Linnaeus)
Quantitative kidney ultrasound from macroscale to microscale
Creators: name: Singla, Rohit Kumar
Publisher: name: University of British Columbia
Year: 2023

description: Chronic kidney disease impacts 1 in 10 adults globally, with exponential increases in hospitalization, adverse cardiovascular events and mortality risk. Those who reach end-stage kidney disease require renal replacement therapy, a significant burden on a patient’s quality of life and on the Canadian healthcare budget. Serum and urine biomarkers of kidney disease are insensitive, potentially producing false negative re- sults, whereas tissue biopsy is an invasive procedure that is not routinely performed and comes with complications such as bleeding and infection. There is a need for non-invasive characterization of the kidney. This thesis investigates several methods of kidney tissue characterization, ranging from the macro whole-organ scale to the microstructural scale, using ultrasound imaging methods and machine learning. It presents an open detailed high quality data set for kidney segmentation, with a demonstration of how automatic morphological measurements can be obtained in clinical ultrasound settings using machine learning. This automated measurement is comparable to human experts. It contributes how physics-based data augmentation techniques can improve the robustness of such algorithms, showing that a time-gain compensation augmentation reduces algorithmic uncertainty. It then investigates the speckle properties of transplanted kidneys, showing such properties are patient- and machine-agnostic. This study also identifies the Nakagami distribution as the best model of speckle in the kidney. Subsequent work demonstrates that ultrasound images alone can be used to predict kidney decline in transplant recipients, with speckle parameters being amongst the most prognostic. Finally, quantitative ultra- sound parameters are measured in a murine study. The results show the versatility and accuracy of quantitative ultrasound to characterize the kidney, and enabling a non-invasive method for quantifying kidney disease.
Mississippi CRP Forest Remote Sensing with Preliminary Global Ecosystem and Dynamics (GEDI) Mission Derived Data Products
Creators: name: Degagne, Rebecca
name: pizzino, declan
name: gough, mike
name: friedrich, hannah
name: smith, charlotte
name: Joseph, Gladwin
name: Iovanna, Rich
name: Strittholt, James
Publisher: name: figshare
Year: 2022
Subjects: subject: 70504 Forestry Management and Environment
subject: FOS: Agriculture, forestry and fisheries
subject: 70104 Agricultural Spatial Analysis and Modelling
subject: FOS: Other agricultural sciences
subject: 80605 Decision Support and Group Support Systems
subject: FOS: Computer and information sciences
subject: 50209 Natural Resource Management
subject: FOS: Earth and related environmental sciences

description: CBI initially developed predictive maps of tree height, tree density, biomass, basal area, and forest type using Random Forest machine learning models. Numerous satellite-derived indices from the European Space Agency’s (ESA) Sentinel-1 and Sentinel-2 sensors, in addition to soils and topography data, were used as predictor inputs. We then refined these predictive models, focusing primarily on biomass improvements, by implementing new methods for processing Sentinel-1 imagery on the cloud computing platform Google Earth Engine (GEE); significantly updating model code; and incorporating preliminary data products derived from NASA’s spaceborne LiDAR mission - the Global Ecosystem Dynamics Investigation (GEDI). We refined the GEDI LiDAR-derived data products and included them in our models, and overall accuracy for the four forest regression models ranged from 57% to 91%. The Biomass model saw the greatest improvement in accuracy with the R2 increasing by 8%, from 49% to 57%. The Basal Area and Tree Height models both had minor 1-2% increases in accuracy, while the Tree Density model had no improvement. The Forest Type classification model had a negligible improvement in overall accuracy, however, the Elm/Ash/Cottonwood class increased in accuracy by ~6%, from 64% to 70%.
title: EXPLORING ENTREPRENEURSHIP EDUCATION USING PROJECT-BASED LEARNING IN A BUSINESS MANAGEMENT PROGRAMME AT A CANADIAN COLLEGE
Creators: name: Kennedy, K
Publisher: name: University of Liverpool Repository
Year: 2018

description: Entrepreneurship is a key driver of our Canadian economy. Statistics Canada states that almost 20% of all jobs in Canada are created by small businesses and self-employment. In order to ensure a steady supply of qualified entrepreneurs for our labour markets, educators must be able to provide support and resources to their students that will enable their new businesses to succeed and in turn boost our economy. This is where entrepreneurial education can play a powerful role in creating a continuous and competent supply of entrepreneurs supporting strong economic growth in the Canadian economy. Attempting to ensure consistent entrepreneurial growth, the Alberta Provincial Government prompted changes in post-secondary education by mandating colleges to provide more effective entrepreneurial learning environments for their students. Olds College, a small rural college in central Alberta accepted the Alberta Provincial Governments challenge, opening the door for a research opportunity which would test the plausibility of a proposed programme change. A formative research methodology was deemed the most appropriate methodology to use in this research opportunity which examined the plausibility of a change in teaching method within the business management programme at Olds College, in Alberta, Canada. This research study served two purposes: 1) To develop a learning model and decision matrix tool built upon existing literature to help better understand effective entrepreneurial teaching and learning. 2) To test the plausibility of successfully implementing a project-based teaching method into the business management diploma programme at Olds College. The plausibility of successful implementation of this teaching method was tested through a pilot project which spanned over a three-year period, collecting data through semi-structured interviews, surveys, observations, and analysis of peer-reviewed research and other scholarly literature. The formative research method provided ongoing results that informed continuous improvement changes as the three iterations of the study were completed. The data gathered from the student, instructor and leadership surveys and interviews delivered valuable feedback that informed the decision-making process and provided the incentive to move forward with Entrepreneurial Learning – Kennedy 2017 3 business management programme changes. The implementation of a project-based Pedagogy for the Business Management diploma programme at Olds College, started in the 2017/2018 academic year providing an entrepreneurial focus for the business programme and ensuring a better fit within the organizations strategic plan
title: A case study of a university-industry partnership (UIP) in science and technology: What drives extraordinary performance?
Creators: name: Campbell, Neil
Publisher: name: University of Liverpool Repository
Year: 2018

description: Background In the 21st century knowledge economies, the creation of knowledge is important for the advancement of society through innovation and economic development. Open innovation has been the knowledge creation and utilisation process whereby universities and industry work in partnership to advance economic means. These university-industry partnerships (UIPs) historically have made the universities more entrepreneurial in their knowledge pursuits and industry more research and development oriented. Purpose The purpose of this thesis is to research a single case study involving the University of Liverpool and Unilever Corporation through the interactions within a Centre for Materials Discovery (CMD). The partnership between the parties is notable for its sustained and extraordinary success in the discovery of new chemical entities (NCEs) for new product development. Findings of the empirical research will advance the knowledge for the design, formation and operation of an UIP by innovation professionals. Methodology A qualitative research method with ethnography approach to inquiry through access of a singlecase study. The study utilised semi-structured, open-ended interviews with past and present UIP participants. The researcher was embedded as a participant-observer within the UIP. The methodology will be used to build a rich understanding of the practices of the CMD UIP. 3 Findings The research findings discovered five key categorical themes that drove the sustained extraordinary success of the CMD UIP. Interwoven into these five categorical themes were two cross-cutting global themes that added more synergy and depth to the findings. Originality The literature is sparse on sustainability of extraordinary performance within UIPs. The CMD UIP was notable for sustained and extraordinary outputs that make the empirical findings a contribution to the literature regarding UIPs for innovation professionals. Conclusions This thesis is a single case study of the University of Liverpool, United Kingdom and Unilever Corporation’s partnership centered on high-throughput chemistry compound discovery for consumer products in the hygiene, personal care and retail markets. This partnership has produced multi-billion dollar revenues for Unilever in new products and advanced the research stature for a major university. Based upon the empirical findings, I have constructed an actionable framework that can be used by innovation professionals when designing, organising and operating UIPs in the knowledge economies of the 21st century.
title: Managing in conditions of extreme market volatility A case study of the Middle East operations of a multinational agribusiness
Creators: name: Hanbaly, Mohamad
Publisher: name: University of Liverpool Repository
Year: 2018

description: During the last ten years market volatility in the Middle East has increased significantly for several reasons. The political and economic instability resulting from wars, international sanctions, fluctuations in oil prices and exchange rate has resulted in a continually uncertain market environment. Multinational companies within the agribusiness industry have faced additional challenges for sustainable operations in the face of climate change. Such companies have sought management solutions that maintain stability within their operations despite the emergent challenges in this sector. The objective of the research is to cultivate actionable strategies for the improved management of the Middle East operations within one multinational agribusiness faced with a volatile market environment. The research draws upon a range of concepts within the academic literature that relate to management in conditions of market volatility: agility, flexibility, adaptability, responsiveness, and absorption. These concepts are used to inform my engagement with managers within a leading agribusiness multinational operating in the Middle East. The research methodology comprises a number of stages. Firstly, qualitative interviews were held with managers across a range of functions to both understand the current operation and to deliver the evidence for the development of actionable strategies for improving operational management. Secondly a thematic analysis of the interview data led to the generation of an actionable framework for effective management in response to market volatility. Finally, this model was “tested” with senior managers through engagement process to collaboratively generate actions that enhance management of volatility for the case studied organization. The actionable framework is meant to be holistic in its approach towards Middle East market management and addresses volatility across three key imperatives: (1) The organization to be market driven; (2) Management to develop strategies for the three distinct phases related to market penetration, responding to volatility and learning from volatile episodes; (3) Management to develop actions plans within three operational categories of “agile performance”, “optimized response” and “agile capability”. The prioritized action area concerned the development of hybrid management committee between functions and HQ/local. The timescale of this DBA research (cf full implementation of the actions) has not allowed an evaluation of this hybrid committee. The thesis concludes with reflections on both the implications for managers operating in comparable volatile environments, and the implications for my own professional practice.
A LOOK AT THE HISTORY OF FRENCH AND UZBEK TRANSLATION: THE TRANSLATION OF CHOLPON'S "NIGHT AND DAY" INTO FRENCH LANGUAGE
Creators: name: Ruzimurodova, Fariza
Publisher: name: Zenodo
Year: 2023

description: It is no secret to any of us that every nation strives to develop its spiritual world by improving its traditional values based on its goals and objectives, and at the same time, on the basis of the achievements of universal development. After all, the sense of historical memory is fully restored, and the path of the nation with all its successes and ups and downs, losses and victims, joys and sufferings is studied impartially and truthfully.
UNTERSUCHUNGEN ÜBER DIE LEPIDOPTERENFAUNA DES ÖSTLICHEN TEILES DES MECSEKGEBIRGES (SW-UNGARN) V. DIE SCHMETTERLINGE (LEPIDOPTERA) DES KASTANIENWALDES VON ZENGŐVÁRKONY
Creators: name: Fazekas, Imre
Publisher: name: Zenodo
Year: 1985

description: Nocturnal moth species survey in southern Hungary (Mecsek Mountains). The habitat is an old-growth forest of chestnut trees. The height above sea level is 300 m. The species observed are listed, and the flight times of the adults. This is the first publication from Hungary to investigate the butterfly fauna of the chestnut forest. The author concludes that the Castnea sativa is not native to Hungary and was probably introduced to this area in the Roman period.
description: Nocturnal moth species survey in southern Hungary (Mecsek Mountains). The habitat is an old-growth forest of chestnut trees. The height above sea level is 300 m. The species observed are listed, and the flight times of the adults. This is the first publication from Hungary to investigate the butterfly fauna of the chestnut forest. The author concludes that the Castnea sativa is not native to Hungary and was probably introduced to this area in the Roman period.
Exploration of rare mitochondrial DNA mutations in lymphocyte subsets of people living with human immunodeficiency virus
Creators: name: Caloren, Loïc
Publisher: name: University of British Columbia
Year: 2023

description: Despite advancements in Human Immunodeficiency Virus (HIV) therapy in extending lifespan and preventing AIDS, people living with HIV (PLWH) experience premature aging mainly indicated by higher prevalence and earlier onset of age-related diseases compared to HIV-negative controls. The mechanism of this aging remains unclear; however, some immune system effects observed in HIV are also characteristic of aging. Mitochondrial dysfunction, a hallmark of aging, may be linked to HIV and its treatment, which are known to affect mitochondrial DNA (mtDNA) and function. Further, mtDNA mutations are associated with aging and age-related diseases. In this regard, low frequency (<1%) mtDNA mutations have become subject to growing interest. The interplay of mtDNA mutations and immunosenescence is unknown as rare mtDNA mutations have never been characterized in lymphocyte subsets. The goal of my research was to explore rare mtDNA mutations in lymphocyte subsets of PLWH. First, I successfully adapted a unique molecular identifier (UMI)-based sequencing assay to enable sequencing of low concentration mtDNA specimens, necessary for my assaying of sorted lymphocyte specimens. I then sequenced a 264bp segment of mtDNA in the mitochondrial control region of: whole blood, CD4+ T cells, proliferative-competent (CD28+) CD8+ T cells, senescent (CD28-) CD8+ T cells, and B cells (CD19+) in 271 specimens from 48 PLWH and 41 HIV-negative controls. My analyses revealed a pattern of mtDNA variants with specific positions appearing as hotspots in the interrogated region, almost exclusively transition mutations (A↔ G, C↔ T). Total mutation burden differed slightly between lymphocyte subsets, however the distribution of mutations across genome position in each subset agreed closely with each other and with whole blood. No significant associations were observed with HIV status in any of the subsets. My research is the first to characterize rare mtDNA mutations in lymphocyte subsets, offering new insight into the composition of mtDNA mutation burden of whole blood. More research is needed to elucidate the extent of interplay between mtDNA mutations, immunosenescence and aging in HIV. Together, my findings facilitate future studies by validating a modified assay for specimens with low mtDNA concentrations and informing the use of whole blood to study mtDNA mutations.
title: Tomorrow’s Eco-city in China: Eco-City Development though a Culture of Collaborative Communication
Creators: name: Wang, X
Publisher: name: University of Liverpool Repository
Year: 2018

description: The delivery of Chinese eco-cities has met certain challenges in plan-making and the subsequent implementation of planning documents. Meanwhile, communicative and collaborative planning has been advocated as a method that can assist in decision-making and facilitating urban development in China. In the development of the ‘eco-city’, communicative and collaborative planning has met certain barriers to implementation, and has thus played a limited role in the planning system. This research aims at examining whether a communicative turn has occurred in the delivery of eco-cities with regard to sustainable development in China, discusses how communicative and collaborative planning could help to improve the development of Chinese eco-cities, and examines the methods that can achieve this. To provide an update on the difficulties of communication and collaboration in planning work, the development programmes of the Sino-Singapore Tianjin Eco-city and the Shanghai Dongtan Eco-city are reviewed and compared. The Tianjin Eco-city was approved by central government as one of several pilot areas for developing eco-cities; the Dongtan Eco-city was suspended and failed to achieve its original vision. Data and evidence was collected from the planning documents in both Tianjin and Dongtan, and combined with data collected from interviews with 12 key persons who directly engaged in the delivery of the eco-city programme in China. Along with emerging technologies, local authorities are facing new challenges and opportunities in adopting communicative and collaborative planning. The study concludes that an extensive implementation of communicative and collaborative planning, through both traditional and emerging technologies, is required to reconcile the diverse interests of stakeholders and address the multi-disciplinary issues in the sustainable development of the Chinese eco-city. The major outcome of this study, as the final part of the thesis demonstrates, is a series of recommendations to mitigate issues during the delivery of Chinese eco-cities. According to these recommendations, a practical framework is developed to adopt a communicative rationality in the current Chinese planning system to facilitate the planning process of an eco-city programme in the field of plan-making, implementation, and monitoring. The study also contributes to stakeholder engagement through advancing a modified and innovative approach to dealing with the barriers to communicative activities and consensus building in the development of the eco-city programme in China.
Geomorphology of the southwest Sinus Sabaeus region: evidence for an ancient hydrological cycle on Mars
Creators: name: Robas, C.
name: Molina, A.
name: López, I.
name: Prieto-Ballesteros, O.
name: Fairén, A. G.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified

description: We have produced a 1:650,000 scale geomorphological map of the southwest Sinus Sabaeus, a region of Mars approximately centered at 25.0°S and 6.5°E and located in the topographic transition between Arabia Terra and Noachis Terra, in the Martian highlands. This heavily cratered region, subjected to extensive surface erosion, shows a complex valley network system known as Marikh Vallis. In this work, we study the history and role of water in and around Marikh Vallis, focusing on the modification and evolution of this area during the earliest Martian times, the Noachian period. The map described in this paper was produced through the analysis of a combination of available imagery data, topography, and thermal inertia, which together allow defining different geomorphological units in this area. This new map provides a basis for identifying the ancient presence of water in the region, both in the liquid state and in the ice phase.
From short GRBs to neutron star natal kicks
Creators: name: Gaspari, Nicola
name: Levan, Andrew J.
name: Church, Ross P.
Publisher: name: Zenodo
Year: 2022
Subjects: Gamma-ray bursts (GRBs)
Multi-messenger astronomy

description: The detection of GW 170817 and GRB 170817A secured the connection between binary neutron star (BNS) mergers and at least some short-duration gamma-ray bursts (sGRBs). Since the number of mergers detected through gravitational waves is still small, we can exploit the BNS-sGRB connection to study the physics underlying BNS mergers through the much larger and variegated sample of sGRBs. Here I present a sample of sGRBs with their putative host galaxies, and discuss the implications for neutron stars' natal kicks. The sample is built on the literature and enhanced with an additional host catalogue from archival observations and a recent robust distinction between long- and short-GRBs based on a machine learning approach. For each host, I reproduce the galactic potential from observations and seed synthetic binary stars in it, to then evolve their orbits and record the location of BNS mergers. This allows me to compare the actual locations of sGRBs with those expected from population synthesis, and test the requirements on natal kicks to explain the observed sGRB population.
description: {"references": ["Abbott et al. (2017). arxiv:1710.05834", "Fong et al. (2013). arXiv:1302.3221", "Zevin et al. (2020). arXiv:1910.03598", "McCarthy et al. (2020). arXiv:2007.15024", "Jespersen et al. (2020). arXiv:2005.13554", "Kormendy & Freeman (2004). arXiv:astro-ph/0407321", "Thomas et al. (2009). arXiv:0809.3906", "Church et al. (2011). arXiv:1101.1088", "Hurley et al. (2002). arXiv:astro-ph/0201220", "Bovy (2015). arXiv:1412.3451"]}
Homogeneity across outcomes reported in prehabilitation randomised controlled trials
Creators: name: Jiang, Wilson
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Medicine and Health Sciences
subject: prehabilitation
subject: core outcome sets
subject: outcome reporting quality
subject: COS

description: Authors: Wilson Jiang Kilian G.M. Brown, MBBS BBiomed MPhil FRACS Cherry Koh, MBBS (Hons), MS (Colorectal Surgery), FRACS Sascha Karunaratne, BHlthSci(Hons)/MPhty Michael Solomon, MB BCH (Hons), BAO, MSc, DMedSc(Syd), DMed (NUI) Paula R. Beckenkamp, BPhty (Hons), PhD, APAM Ruby Cole, BSc Daniel Steffens, BPhty (Hons), PhD
title: The Enumerative Geometry of Double Covers of Curves
Creators: name: Van Zelm, J
Publisher: name: University of Liverpool Repository
Year: 2018

description: Let Adm(g, h)_2m be the space of admissible double covers C → D of curves of genus g and h, with all the ramification and branch points of C and D marked, and where the covering involution permutes an extra set of 2m marked points of C pairwise. For each 0 ≤ n ≤ 2g +2−4h there is a natural map φ_n : Adm(g, h)_2m → Mbar_g,n+2m mapping the admissible cover C → D to the stabilization of the source curve C together with the 2m points and the first n ramification points. In this thesis we will study classes of the form [φ_n (Adm(g, h)_2m )] in the Chow ring of Mbar_g,n+2m . We will derive a formula for the intersection of any such class with the class of any decorated stratum class of Mbar_g,n+2m in Chapter 2. In Chapter 3 we will use this formula to compute the class [φ_n(Adm(g, h)_2m)] in terms of bases of decorated stratum classes for low values of g, h, n and m. In particular we give explicit expression in terms of decorated stratum classes of the class [φ 0 (Adm(4, 1))] of the locus of bielliptic curves of genus 4 and the class [φ 0 (Adm(5, 0))] of the locus of hyperelliptic curves of genus 5. In Chapter 4 we will prove that for g + 2m ≥ 12 and g ≥ 2 the class [φ_n(Adm(g, 1)_2m)] is not contained in the tautological ring. For g + 2m = 12 and g ≥ 2 we will show that the same result holds on the moduli space M_g,n+2m of smooth curves.
title: The influence of online logistics service mode on customer loyalty: the moderation effect of signal credibility and switching costs
Creators: name: He, Y
Publisher: name: University of Liverpool Repository
Year: 2018

description: With the fast development of society and technology, customers’ demand for homogeneousness is gradually decreasing, while the demand for diversification and customisation is increasing. In this sense, online logistics service mode (OLSM) emerges to better satisfy customers’ needs. OLSM is a kind of customised service provided by the online retailer, which consists of several logistics elements such as delivery time, logistics service provider and so on. In particular, it enables customer to choose their preferred delivery time and ways to delivery, as well as decrease customer’s perceived uncertainty, which further enhances customer loyalty. The provision of OLSM requires more investment from online retailers and brings more complexity. Although it could enhance customers’ loyalty to some extent, many online retailers in China still hesitate to provide such customised service since there is a lack of theory or research to show the mechanism about how OLSM affects online customer’s loyalty. Hence, the aim of this dissertation is to examine the relationship between OLSM and e-loyalty, and to seek for how OLSM affects e-loyalty based on signalling theory and relationship marketing theory. Seven basic hypotheses were tested, as parts of a theoretical model. Data was collected through a questionnaire and statistical analysis software such as SPSS, AMOS and EXCEL was used to analyse the data to check the reliability, validity, and test the proposed hypotheses. The empirical results reveal that OLSM positively influences relationship quality (e-satisfaction, e-trust and e-commitment), and relationship quality positively affects e-loyalty; OLSM positively influences e-loyalty via relationship quality; signal credibility moderates the relationship between OLSM and relationship loyalty, and the mediation effect of relationship quality on the relationship between OLSM and e-loyalty; switching costs moderates the relationship between e-satisfaction and e-loyalty, and the mediation effect of e-satisfaction. This research contributes to knowledge in several ways. Most importantly, it defines the definition of OLSM and discovers the mechanism about how OLSM affects e-loyalty. In addition, it discusses the moderation effect of logistics service price from the perspective of signalling theory.
title: Probing the structure, self-assembly, and nanomechanics of bacterial microcompartments
Creators: name: Faulkner, M
Publisher: name: University of Liverpool Repository
Year: 2018

description: Bacterial carbon fixation activity accounts for a significant proportion of global carbon capture. Bacteria do not have the complex carbon concentrating mechanisms and membrane bound organelles of plants and yet they have incredibly high photosynthetic efficiency. This is, in part, because of the alternative carbon concentrating mechanism bacteria employ involving the carboxysome. Carboxysomes are a type of bacterial microcompartment, a proteinaceous structure comprised of an outer semi-permeable shell encapsulating an internal enzyme filled lumen. By encapsulating the enzyme Rubisco, that catalyses the often rate limiting step of carbon fixation, carboxysomes are able to boost catalytic efficiency. Carboxysomes therefore increase overall carbon fixation activity. Bacterial microcompartments are widespread amongst bacterial phyla and apply the same approach to many enzymatic reactions. Our knowledge of the structure of carboxysomes and other such compartments and how they self-assemble is limited. This is thereby preventing the successful use of recombinant compartments to boost enzymatic efficiency in synthetic systems, plants, and other organisms. In this work, a multifactorial approach is employed to study the carboxysome, from the initial self-assembly of monomeric protein building blocks to the structural and mechanical properties of the entire functional compartment. Novel observations include the first application of near-native high-speed atomic force microscopy to the study of a purified micro-compartment shell protein and the first purification and characterisation of intact carboxysomes, from the widely studied model organism Synechococcus elongatus PCC 7942. Also the first direct functional and structural comparison of two different kinds of carboxysome, α and β, from different model-bacteria. Previously unobserved protein dynamic events within tiled arrays of shell proteins were recorded. These data shed light on the mechanisms of the initial stages of micro-compartment self-assembly. These data also gave rise to the first clear evidence that manipulating the interactions between individual amino acids in bacterial microcompartment shell proteins can control self-assembly. The mechanical properties of carboxysomes were identified as potential biomarkers to evaluate future synthetic carboxysome constructs through atomic force microscopy and nanoindentation.
השפעת תכני "פיטספיריישן" ברשתות חברתיות כתלות ברמת חיפצון העצמי על תפיסת דימוי הגוף
Creators: name: Barak, Maayan
name: Karlin, Daniela
name: Bakunin, Ariela
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: זוהי הרשמה מראש למחקר שלנו במסגרת הקורס פסיכולוגיה ניסויית באונ' ת"א.
solving differential equation by means of neural networks
Creators: name: aslam, muhammad junaid
Publisher: name: Zenodo
Year: 2023

description: Artificial neural networks, or neural networks, represent a technology thatis rooted in many disciplines like mathematics, physics, statistics, computer science and engineering. Neural networks have various applications in the area of mathematical modelling, pattern recognition, signal processing and time-series analysis, etc. It is an emerging field for researchers and scientists in the industry and academics to work on.
title: An investigation of the effect of route to university on UK Business School students’ experiences of a professional mentoring scheme
Creators: name: Clarke, J
Publisher: name: University of Liverpool Repository
Year: 2018

description: This thesis presents a Bourdieusian analysis of a mentoring scheme in order to understand whether it may develop social capital at the individual level. Differential rates in the acquisition of sought after graduate jobs suggest that higher education is not facilitating fair access to what is a limited supply of graduate-entry, high status, well-paid careers. As such, there is a need to understand how universities might best support their students who come from groups traditionally underrepresented in higher education in obtaining graduate level employment. This thesis seeks to make a contribution to knowledge in this area; it offers an evaluation of the effectiveness of a mentoring scheme run in a Russell Group University Business School in preparing students for and connecting them with the world of work. The research aims to create knowledge about how students from different backgrounds experience and benefit from mentoring by business professionals. It tests the application of Bourdieu’s theoretical framework to the professional mentoring scheme and makes some proposals as to how Bourdieu’s theories might be refined. The insights gained from the study are used to offer suggestions for the design of future mentoring schemes to ensure that they optimise value to students from non-traditional backgrounds.
Polycomb repressive complex 2 related syndromes : functional studies of human gene variants In Drosophila
Creators: name: Cyrus, Sharri Sonjene
Publisher: name: University of British Columbia
Year: 2024

description: The Polycomb Repressive complex 2 is an epigenetic regulator responsible for the mono-, di- and trimethylation of histone 3 lysine 27. Pathogenic mutations in the core members of the complex, namely EZH2, EED and SUZ12 cause the childhood-onset diseases Weaver syndrome, Cohen Gibson syndrome and SUZ12-related overgrowth respectively. Additionally, somatic mutations in these genes are seen in a variety of solid tumours and blood malignancies, and individuals with Weaver syndrome have a 5% risk of cancer development in the first 25-30 years of life. As exome and genome studies become more routine in clinical practice, classifying and reporting rare variants in genes associated with diverse clinical outcomes will become more complex and varied. Thus, detailed phenotyping of individuals with variants in these genes paired with functional studies is essential to truly characterise the effect of PRC2 variants in human populations. In this work we use now-published clinical data to generate a phenotypic summary of Weaver syndrome, Cohen Gibson syndrome and SUZ12-related overgrowth. We show that these syndromes are typically characterised by neurodevelopmental delay and overgrowth, with the variable presence of abnormalities in other organ systems. As SUZ12-related overgrowth was the most recently described syndrome, we describe an additional 10 individuals, further expanding the clinical phenotype and increasing the reported case count from 3 to 13. To bridge genotype to function, we use Drosophila melanogaster to develop inexpensive and robust assays with the capacity to screen hundreds of variants. We use a combination of strategies including CRISPR/cas9 editing, ΦC31-mediated Recombinase-mediated cassette exchange and ΦC31-transgenesis to express human and orthologous Drosophila transgenes to interrogate human PRC2 variants. Despite the conservation of PRC2 between humans and Drosophila, we show here that expression of EZH2 or EED variant human proteins within Drosophila is not very effective in quickly or accurately interrogating variant function. However, creating EED or EZH2 mimetic or analogous human mutations in the fly’s orthologous gene or cDNA is a successful strategy that can be used to investigate loss-of-function (LoF) effects of variants. Moreover, we present EED assays that can accurately discern between LoF EED variants and benign variants.
title: A Direct Method for Bloch Wave Excitation by Scattering at the Edge of a Lattice
Creators: name: Brougham, RI
Publisher: name: University of Liverpool Repository
Year: 2018

description: A new method for calculating the reflection and transmission properties of lattices is developed and demonstrated for the case of a semi-infinite lattice of sound-hard and sound-soft acoustic scatterers. Both point-scatterers and finite-sized scatterers are considered, with generalisation from the former to the latter being considerably simpler than previous approaches to this problem.
Temporal dynamics of the affective versus semantic representations of valence during reversal learning with two states
Creators: name: Hertz, Uri
name: Heimer, Orit
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Discount factor
subject: Affective valence
subject: Reversal learning
subject: Semantic valence

description: The study will examine the discount factors of the semantic and affective representations of valence during reversal learning with two states.
Anatomical and physiological adaptation of camel to desert environment
Creators: name: Pratap Gore1, Jaskiran Kaur2, Rakesh Kumar2
Publisher: name: trends in Agriculture Science
Year: 2024

description: The dromedary (Camelus dromedaries), also called Arabian camel or one humped camel. It is able to survive in hot dry desert due to anatomical structure. Anatomical adaption any alteration in the structure or function of an organism the organis becomes better fitted to survive and multiply in its environment. Adaptation of animal to its environment in general is used often for the process of adjustment to the environmental changes. The camel, however is able to utilize these mechanisms more effectively when exposed to the direct rays of the sun and for extremely long periods without drinking water. The orbit is circular, equidistant, completely osseous and markedly projecting laterally. Camel has long double eyelashes and a nictitating eye membrane to protect the eyes from the sun and sand. It also has closable nostrils. It breathes slowly with no panting. The lips are thick to help the camel eat the prickly shrubs. There is a thick coat of hair even inside the camel’s ear. The legs are long and thin with thick covers on knees. Hooves have a broad, flat leathery pad. Camel body temperature keeps fluctuating from 34°C to 41.7°C (93°F-107°F.). This helps the animal sweat less.
Queuing, social interactions, and the microstructure of financial markets
Creators: name: Horst, Ulrich
name: Rothe, Christian
Publisher: name: Humboldt-Universität zu Berlin
Year: 2008
Subjects: subject: Microstructure of Financial Markets
subject: Social Interaction
subject: Queuing Networks
subject: 330 Wirtschaft

description: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
description: We consider an agent-based model of financial markets with asynchronous order arrival in continuous time. Buying and selling orders arrive in accordance with a Poisson dynamics where the order rates depend both on past prices and on the mood of the market. The agents form their demand for an asset on the basis of their forecasts of future prices and their forecasting rules may change over time as a result of the influence of other traders. Among the possible rules are “chartist” or extrapolatory rules. We prove that when chartists are in the market, and with choice of scaling, the dynamics of asset prices can be approximated by an ordinary delay differential equation. The fluctuations around the first-order approximation follow an Ornstein–Uhlenbeck dynamics with delay in a random environment of investor sentiment.
Social Relationships Lab
Creators: name: Brand, Daisi R.
name: Hu, Hannah
name: Hernandez, Andrea
name: Leckfor, Christina M.
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Psychology
subject: FOS: Psychology
subject: Social and Behavioral Sciences
subject: Social Psychology

description: This is an amendment to the Interparental Relationships and Young Adult Relationships Study pre-registration.
مصادر استقاء الأفكار العلمية الإبداعية في مجال المكتبات والمعلومات دراسة ميدانية لاتجاهات الباحثين العرب
Creators: name: زكريا،محمود شريف احمد
Publisher: name: Zenodo
Year: 2016
Subjects: الأفكار العلمية الإبداعية | التفكير الإبداعي | علم المعلومات | البحث العلمي | الكتابة الأكاديمية

description: تبحث الدراسة في اتجاهات عينة من الباحثين العرب في مجال المكتبات والمعلومات نحو مصادر استقائهم الأفكار العلمية الإبداعية، كمرحلة أولية في مشروع البحث العلمي، بحيث تم التحقق من مصادر استقاء الأفكار العلمية الإبداعية التي يقصدوها هؤلاء الباحثون، وما تعلق بدوافعهم نحو ابتكار الأفكار الإبداعية الجديدة، فضلا عن المعوقات أو التحديات التي يلقونها إزاء ذلك. وعليه، تم الاعتماد على المنهج الميداني، استنادا إلى استبانة، وزعت إلكترونيا على مجتمع الدراسة، بحيث بلغ عدد الاستجابات المسترجعة نحو ٢٢٠ استبانة، تم تحليلها إحصائيا باستخدام برنامج الـ SPSS. وقد أسفر التحليل عن جملة من النتائج؛ لعل من أهمها: أن أبرز مصادر استقاء الأفكار العلمية الإبداعية التي أبدى أفراد العينة اتجاههم نحوها تمثل في كل من: "القراءة في مجال التخصص" (72.2%)، و"البحث في الإنتاج الفكري" (54.5%)، و"حضور اللقاءات العلمية" (51.8%)، بينما تركز أبرز دوافع البحث عن الأفكار العلمية الإبداعية في كل من: "الإضافة الجديدة إلى المعرفة الإنسانية" (82.7%)، و"مواكبة الاتجاهات الحديثة" (80.9%)؛ و"الإيمان بقيمة الفكرة الجديدة" (76.4%)، وفيما يتعلق بمعوقات استقاء الأفكار العلمية الإبداعية، فكان أهمها: "ضغوط العمل" (64.5%) و"عدم توافر الدعم المناسب" (60.5%)، و"عدم اكتراث المجتمع بأهمية الفكرة الإبداعية" (53.2%)، وغيرها. وفي النهاية تقدم الدراسة للباحث العلمي في مجال المكتبات والمعلومات مجموعة من التوصيات والإرشادات التي تعينه بالضرورة على استقاء الفكرة العلمية الإبداعية الجديدة في مجال اهتمامه، بحيث يقدم إنتاجا علميا جديدا غير مسبوق.

 This study aims at reveal the attitudes of a sample of Arab researchers in Librarianship & Information Science (LIS) towards the best resources of extracting scientific ideas, and to discuss both of motivations and challenges that related to selecting the statement of the study. A questionnaire was designed in order to gather data. The results indicate that the most important resources of extracting scientific ideas are: 'Specialized Reading' (72.2%), 'Literature Searching' (54.5%), and 'attendance scholarly events' (51.8%). The motivations of searching about scientific ideas focused on the following: 'the new addition to the knowledge' (82.7%), keeping up with the modern trends' (80.9%) and 'the importance of new ideas' (76.4%). Regarding to the challenges that scholars may find, the study revealed the following: 'work stress' (64.5%), 'lack of support' (60.5%), and some another difficulties.
snap judgement
Creators: name: Goldfarb, Shahar
name: Moallem, Mai
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: כחלק מקורס ״פסיכולוגיה ניסויית״, ברצוננו לבדוק כיצד הדיוק של הרושם הראשוני בהסקת תכונת מסוגלות לגבי פוליטיקאים מושפע ממשתנים שונים כגון גיל הנבדק ותפעול של לחץ זמן בקבלת ההחלטה. מחקרים קודמים מראים כי הסקה של תכונות על בסיס מראה בלבד רלוונטית בניבוי האופן בו התכונות הנ״ל נתפסות בקרב הציבור. כמו כן, אנשים מבוגרים נוטים להתבסס על משתנים רבים יותר ביחס לאנשים צעירים בתהליך יצירת הרושם הראשוני. בנוסף, מחקרים קודמים מראים כי תחת לחץ של זמן אנשים נוטים להפעיל קיצורי דרך )היוריסטיקות( בהם תהליכי החשיבה מואצים ועוברים סינון. כלומר, דפוס החשיבה משתנה בצורה אדפטיבית תחת ׳איום׳ הזמן.
Frontal instability and energy dissipation in submesoscale fronts
Creators: name: Peng, Jen-Ping
Publisher: name: Universität Rostock
Year: 2020
Subjects: subject: 550 Earth sciences

description: Theory and numerical simulations suggested that submesoscale fronts and filaments are subject to various types of instabilities, providing a potentially important pathway for the downscale transport and dissipation of mesoscale kinetic energy in the ocean. Based on the observational data collected from the Benguela upwelling system, this thesis, for the first time, provided direct evidence for the detailed structure of turbulence triggered by forced/unforced/inertial symmetric instability and marginal shear instability in submesoscale fronts.