cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ARTIFICIAL INTELLIGENCE AS A BASIS FOR INNOVATION MANAGEMENT IN TOURISM
Creators: name: Muminova Svetlana, R.
name: Tomashevskaya Natalia, G.
Publisher: name: Сервис в России и за рубежом
Year: 2022
Subjects: INNOVATION
NEURAL NETWORK
MACHINE LEARNING
TOURISM
COMPUTER VISION
BIG DATA ANALYSIS

description: The paper overviews theoretical researches and practical applications related to implementation of artificial intelligence (AI) in tourism. Recently, much attention is given to the machine learning algorithms, neural networks and computer visions as promising tools of the digital transformation of tourist industry. Prognostic and classification models build by means of them allow all stakeholders of tourist industry to move to a new level of decision-making process and thus to improve the quality of the service. In particularly, AI-based software enables local authorities not only to measure anthropogenic load in some area, to perform ecologic monitoring of recreation territories and to model their sustainable development, but also to increase safety level for tourists. Transport companies could optimize tourist itineraries and study behavior models of the clients at the moment of buying tickets and hotel and restaurant owners would get more efficient tools for determining preferences of the consumers, the degree of their satisfaction and that would lead to constructing much more efficient relations with them. Another important issue is that neural networks are capable to resolve the problem of fake reviews. Undoubtedly, that will rise the credibility of the information available on internet. Summarizing, AI is becoming a new technological paradigm on the basis of which an innovative management processes in tourism will be designed soon.
title: Agile Entwicklung physischer Produkte
title: Eine Studie zum aktuellen Stand in der industriellen Praxis während der COVID-19-Pandemie
titleType: Subtitle
Creators: name: Nicklas, Simon J.
name: Michalides, Marvin
name: Atzberger, Alexander
name: Weiss, Stefan
name: Paetzold-Byhain, Kristin
Publisher: name: Universität der Bundeswehr München
Year: 2021

description: In der Entwicklung von mechatronischen Produkten nimmt die agile Entwicklung bereits seit einigen Jahren eine zunehmend wichtigere Rolle ein. Im Rahmen dieser Studienserie wird seit 2018 das Fortschreiten der Agilität in der DACH-Region untersucht. In der vorliegenden 2021er Ausgabe liegt der Fokus auf den Bereichen Verständnis, Anwendung, Prototyping sowie Herausforderungen und Auswirkungen der COVID-19-Pandemie. Die Ergebnisse dieser Studie beruhen, wie auch in den vorangegangenen Jahren, auf den Aussagen von Praktikern aus einem breiten Spektrum an Industrieunternehmen, die an einer Online-Umfrage teilgenommen haben. Die Studie beschreibt sowohl quantitative als auch qualitative Ergebnisse aus der industriellen Praxis.
Additional file 1 of Long-term monitoring reveals invariant clutch size and unequal reproductive costs between sexes in a subtropical lacertid lizard
Creators: name: Jhan-Wei Lin
name: Ying-Rong Chen
name: Tsui-Wen Li
name: Pei-Jen L. Shaner
name: Lin, Si-Min
Publisher: name: figshare
Year: 2020
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 1: Figure S1. Monthly capture record of (a) adults; (b) juveniles; (c) recapture rates of all individuals; and (d) male/female composition (green/red) from May 2006 to August 2013. Figure S2. Sexual size dimorphism of Takydromus viridipunctatus.
Expressive handovers: neural and behavioral effects of different attitudes in humanoid actions
Creators: name: Vannucci Fabio
name: Giuseppe, Di Cesare
name: Francesco, Rea
name: Sandini Giulio
name: Sciutti Alessandra
Publisher: name: Zenodo
Year: 2020
Subjects: Vitality
Human-robot Interaction
Biological Motion
Neurophysiological Bases

description: Interacting with others requires the ability to evaluate their attitudes based on how actions are performed. Even a simple everyday act as handing over an object acquires a different meaning if it is performed gently or harshly. This little difference can impact the whole evolution of a collaboration, as people tend to react aggressively to aggressive behaviors. Concerning human-robot interaction, it is important to be aware of the impact that robot motion features might have in the partner’s interpretation of their actions. The challenge we address in this research is to endow the iCub humanoid robot with the capacity to communicate intuitively positive and negative attitudes in its own actions. The results of a series of fMRI and interactive studies showed that robotic passing actions performed with kind and aggressive attitudes (or vitality forms) have a significant impact not only on how the brain processes the observed robotic action, but also on the way the human partners act in response to it.
description: ICRA workshop on Human-robot handover
IMPROVING FOOD ACCESS AMONG LOW-INCOME RESIDENTS THROUGHOUT CLEVELAND COUNTY, NC
Creators: name: Homsi, Luna
name: Nelson, Kimberly
name: Giering, Elizabeth
name: Mottram, Benjamin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: The neighborhood and the built environment is a social determinant of health which impacts public health through geographic areas where people live, work, and play. Healthy food access as a factor within that social determinant highlights the distance, availability, affordability, and utilization of fresh fruits and produce that are present in particular communities throughout Cleveland County. Poor healthy food access has been connected to 28% increased risk for hypertension and 12% increased risk for diabetes. The proposed program and policy aim to bring healthy foods to low-income populations. The program will partner with Farmer’s Fresh Market Initiative to connect locally farmed produce to the community via a driver network, and the policy will incentivize food retailers to open stores in low-income and low-access areas.  
	Keywords: Cleveland County, North Carolina, social determinants of health, neighborhood and built environment, low-income, healthy food access, program, and policy.
Green-based methods to obtain bioactive compounds from Ilex guayusa Loes. using polar solvent
Creators: name: Cadena-Carrera, Santiago
name: Tramontin, Deise Parolo
name: Jacques, Rosângela
name: Scapin, Enelise
name: Müller, José Miguel
name: Hense, Haiko
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: Many biological activities have been reported for the Ilex genus. However, few studies in the literature have reported on guayusa. To address this gap in our knowledge, chemical analysis of guayusa leaves was made. Extracts were obtained by applying Soxhlet, maceration, supercritical CO2 and pressurised liquid extraction techniques, using water and ethanol as solvent/cosolvent. Extracts were evaluated for their phenolic content and antioxidant capacity. The chemical profile was obtained from HPLC. In raw guayusa leaves were identified caffeine (2.27 ± 0.05%), protein (15.31 ± 0.07%) and lipids (11.81 ± 0.14%). Extracts presented the highest phenolic content (156.56 ± 1.32 mg GAE g−1) and the best antioxidant activity (EC50= 61.85 ± 0.21 µg mL−1) when water was used as solvent/cosolvent. Through HPLC, three main substances were determined and quantified in the extracts: caffeine, theobromine and 5-caffeoylquinic acid. Based on these results, guayusa may be considered a natural source of compounds with potential application in the food and pharmaceutical industries.
Stereochemical determination of NMR chemical shifts in marine terpenoids, antheliol and sangiangol B, using DFT calculations
Creators: name: Hanif, Novriyandi
name: Dinelsa, Fabians Faisal
name: Yanti, Henny Dwi
name: Murni, Anggia
name: Tanaka, Junichi
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Stereochemical determination of the flexible trinor-guaiane sesquiterpenoid, antheliol (1a) and the flexible diterpenoid, sangiangol B (2a), isolated from a marine soft coral, Anthelia sp., was supported by quantum chemical calculations of NMR chemical shifts at DFT levels. The relative configuration of antheliol is now revealed, as 1S*, 4S*, 7S*, 10R* as in 1b, whereas sangiangol B (2c) has complete stereochemistry as 1S*, 7R*, 8R*, 10R*, 11R*, 12S*.
IMPROVING FOOD ACCESS AMONG LOW-INCOME RESIDENTS THROUGHOUT CLEVELAND COUNTY, NC
Creators: name: BENJAMIN MOTTRAM
name: ELIZABETH GIERING
name: KIMBERLY NELSON
name: LUNA HOMSI
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: The neighborhood and the built environment is a social determinant of health which impacts public health through geographic areas where people live, work, and play. Healthy food access as a factor within that social determinant highlights the distance, availability, affordability, and utilization of fresh fruits and produce that are present in particular communities throughout Cleveland County. Poor healthy food access has been connected to 28% increased risk for hypertension and 12% increased risk for diabetes. The proposed program and policy aim to bring healthy foods to low-income populations. The program will partner with Farmer’s Fresh Market Initiative to connect locally farmed produce to the community via a driver network, and the policy will incentivize food retailers to open stores in low-income and low-access areas.
Quartierspiegel Mühlebach 2020
Creators: name: (:Unkn) Unknown
Publisher: name: Zentralbibliothek Zürich
Year: 2020
Subjects: subject: 314 Allgemeine Statistiken zu Europa
subject: 710 Städtebau, Raumplanung, Landschaftsgestaltung
subject: 949 Geschichte anderer Teile Europas
subject: Zürich-Riesbach
subject: Quartier
subject: Amtliche Statistik
subject: Bevölkerungsstatistik

description: Die in dieser Ausgabe publizierten Daten beziehen sich zum grössten Teil auf folgenden Zeitabschnitt : 2019
description: Im Gegensatz zu den Quartieren Seefeld und Weinegg finden sich im Quartier Mühlebach nur wenige öffentlich zugängliche Grünflächen. Dagegen gibt es hier rund um die denkmalgeschützten Villen zahlreiche Pärke. Im Verein mit den Restaurants und dem Kleingewerbe verleihen sie dem ruhigen Wohnquartier seinen Charakter.
Additional file 1 of A qualitative study on midwives’ identity and perspectives on the occurrence of disrespect and abuse in Maputo city
Creators: name: Galle, Anna
name: Manaharlal, Helma
name: Griffin, Sally
name: Osman, Nafissa
name: Roelens, Kristien
name: Degomme, Olivier
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1. Topic Guide
Additional file 3 of A qualitative study on midwives’ identity and perspectives on the occurrence of disrespect and abuse in Maputo city
Creators: name: Galle, Anna
name: Manaharlal, Helma
name: Griffin, Sally
name: Osman, Nafissa
name: Roelens, Kristien
name: Degomme, Olivier
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 3. Code frequency per FGD
Secondary metabolites from Gentiana cruciata L. and their anti-inflammatory and analgesic activities
Creators: name: Konya, Rima
name: Reis, Rengin
name: Sipahi, Hande
name: Barta, Anita
name: Hohmann, Judit
name: Kırmızıbekmez, Hasan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: A previously unreported secoiridoid glycoside, cruciatoside (1) was isolated from the aerial parts of Gentiana cruciata L. along with ten known compounds eustomoside (2), eustomorusside (3), gentiopicroside (4), 6'-O-β-D-glucopyranosyl gentiopicroside (5), loganic acid (6), isoorientin (7), isovitexin (8), isovitexin 2''-(E)-ferulate (9), mangiferin (10), and 2-methyl-inositol (11). The chemical structures of the isolates were elucidated based on extensive 1 D and 2 D NMR experiments as well as HRMS analysis. All isolates were evaluated for their in vitro anti-inflammatory and analgesic activities. Compounds 9, 4, and 7 (200 µM) showed moderate anti-inflammatory activity by inhibiting nitrite production from LPS-induced RAW 264.7 macrophage cells, with the inhibition rates of 39.5%, 25.8% and 22.9% respectively without exhibiting substantial cytotoxicity. Besides, 1, 2, 4, and 7 exerted the highest decrease in IL-6 levels. Moreover, compound 4 showed in vitro analgesic activity by decreasing the PGE2 level comparable to the reference drugs.
Solvent Extraction and Complexation Studies of Pyridine-di-Phosphonates with Lanthanides(III) in Solutions
Creators: name: Konopkina, Ekaterina A.
name: Matveev, Petr I.
name: Kharcheva, Anastasia V.
name: Sumynova, Tsagana B.
name: Pozdeev, Anton S.
name: Novichkov, Daniil A.
name: Trigub, Alexander L.
name: Kalle, Paulina
name: Kirsanova, Anna A.
name: Kalmykov, Stepan N.
name: Petrov, Vladimir G.
name: Borisova, Nataliya E.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: In this work, we studied the complex formation (1H, 31P NMR-titration, UV–vis titration, luminescent titration) and solvent extraction of lanthanides with pyridine diphosphonates. The stoichiometry of the complexes was determined: ML and ML2 forms are present. This is confirmed by all of the above methods. It was found that the pyridine ring and P=O groups are involved in the coordination of the metal cation. The coordination environment of the Eu(III) cation was studied more thoroughly using the EXAFS method in solution. Coordination numbers and distances were determined for the complex in solution. The influence of the lanthanide radius on the value of the stability constant was shown. The change in extraction efficiency in the series of lanthanide is described. A new pattern, unusual for other phosphorus-containing ligands, was obtained. To explain the change in the parameters of complexation depending on the system, DFT calculations were carried out. The effect of various initial states of the extracted cations was shown. The initial state with a large amount of nitrates corresponds to a two-phase system during extraction, and with a smaller amount, to a single-phase system with acetonitrile. Additionally, the luminescent properties of the complexes were described in detail as one more applied aspect of the work. .
GREEN TRANSFORMATION OF CONSUMER BEHAVIOR MODEL IN TOURISM
Creators: name: Mishulina Svetlana, I.
Publisher: name: Сервис в России и за рубежом
Year: 2022
Subjects: TOURIST INDUSTRY
SUSTAINABLE DEVELOPMENT
'GREEN' ECONOMY
TOURIST 'GREEN' BEHAVIOR
TOURIST PRODUCT 'GREEN' CONSUMER BEHAVIOR MODEL

description: Insights into the directions and factors for travelers consumer behavior green transformation influence not only the success of travel companies business models innovative green modernization, their market competitiveness, ability to adapt to changes in natural environment and climate, but also the possibility of creating effective mechanisms promoting green behavior of consumers and manufacturers as well as implementation of regional and national strategies, programs and plans for sustainable development. The research was aimed at developing a model for tourist product consumers green behavior as a tool for the tourist industry environmental transformation in the face of growing environmental risks and challenges. Based on the analysis of approaches existing in the national and foreign theoretical definition of the consumer behavior essence and modeling, the identification of factors and current trends in the consumer behavior green transformation, the author's definition of the tourist green behavior and factorial concept model for the tourist product consumer behavior green transformation are proposed. The research theoretical background includes national and foreign scientific papers on tourist product consumer behavior environmental transformation, determining conditions and ways for the transition to a 'green' economic growth, and sustainable development of the tourist industry. The research data background includes analytical and statistical reports of international tourist and nature protection institutions, governmental and nongovernmental analytical centers, governmental statistical service official data, the data of tourist market entities surveys, published case studies, including the analysis of tourist market entities activities. Applied methods of informational monitoring and analysis of national and international scientific databases, systemic analysis, synthesis, patterns identification allowed to make reasonable conclusions. The publication was prepared under the implementation of issue No 1021052404499-3-5.2.1 Theoretical and methodological foundations for the strategic management of the RF recreational and tourist sector innovative development of the FRC SSC RAS state assignment.
PROSPECTS FOR THE DEVELOPMENT OF MILITARY HERITAGE TOURISM IN PRIMORSKY KRAI (CASE OF THE VLADIVOSTOK FORTRESS)
Creators: name: Maltseva Kseniya, A.
name: Kononov Artem Yu.
Publisher: name: Сервис в России и за рубежом
Year: 2022
Subjects: MILITARY HERITAGE TOURISM
FORTIFICATION
VLADIVOSTOK FORTRESS
HISTORICAL HERITAGE
PRIMORSKY KRAI
REGIONAL TOURIST PRODUCT

description: The article analyzes the problems and prospects for the development of military heritage tourism with the evidence from Primorsky Krai. The study notes the significance of military heritage tourism in Russia, due to the rich historical heritage the country possesses. There is general trend for restoration, as well as for adaptation of military heritage sites for tourist purposes. Former fortress complexes, memorials, other structures are being restored, museumified, used as popular tourist sites. Similarly, the number of relevant festivals, events is growing. At the same time, the analysis shows that in relation to these realities, Primorsky Krai can be recognized as the region that has the necessary resources and opportunities for the further development of military heritage programs. The dominant resource is the Vladivostok Fortress, tourist potential of which is just beginning to develop, however, it already allows using various methods, forms of creating a tourist product. Thematic events, exhibitions, excursions, covering not only the ground part of the fortification, but underground components as well are developing today, taking advantage of demand from the local population and foreign tourists. At the same time, during the analysis, certain problems were also identified, and the ways to solve them were proposed.
IMPROVING THIRD-GRADE READING PROFICIENCY IN CLEVELAND COUNTY WITH AN AFTER-SCHOOL EDUCATION AND NUTRITION POLICY
Creators: name: Omolo, Bernard
name: Tran, Jennifer
name: Nelson, Aquilah
name: Cline, Bridgette
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Students who experience persistent food insecurity have shown to have lower mental proficiencies, impaired reading performance, inadequate test scores, and higher dropout rates, which could lead to long-term adverse health effects due to difficulties in understanding and managing their personal health care, such as seeking care before conditions become acute. As nearly 57% of students enrolled in the Cleveland County School District are eligible to participate in the free and reduced meal program, the proposed programmatic policy can help to support students who are at risk of not meeting grade level standards through a combined nutrition and education intervention. The policy will target students in kindergarten through third grade to ensure that these learners will be set up for success as they are promoted to the next grade level.
Additional file 2 of A qualitative study on midwives’ identity and perspectives on the occurrence of disrespect and abuse in Maputo city
Creators: name: Galle, Anna
name: Manaharlal, Helma
name: Griffin, Sally
name: Osman, Nafissa
name: Roelens, Kristien
name: Degomme, Olivier
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2. A plot of the coding structure
Persistent random walk of cells involving anomalous effects and random death
Creators: name: Fedotov, Sergei
name: Tan, Abby
name: Zubarev, Andrey
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Cell Behavior (q-bio.CB)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: The purpose of this paper is to implement a random death process into a persistent random walk model which produces subballistic superdiffusion (Lévy walk). We develop a Markovian model of cell motility with the extra residence variable $τ.$ The model involves a switching mechanism for cell velocity with dependence of switching rates on $τ$. This dependence generates intermediate subballistic superdiffusion. We derive master equations for the cell densities with the generalized switching terms involving the tempered fractional material derivatives. We show that the random death of cells has an important implication for the transport process through tempering of superdiffusive process. In the long-time limit we write stationary master equations in terms of exponentially truncated fractional derivatives in which the rate of death plays the role of tempering of a Lévy jump distribution. We find the upper and lower bounds for the stationary profiles corresponding to the ballistic transport and diffusion with the death rate dependent diffusion coefficient. Monte Carlo simulations confirm these bounds.
description: 20 pages, 1 figure
Aquatic Animal Health Subprogram: Strategic approaches to identifying pathogens of quarantine concern associated with the importation of ornamental fish
Creators: name: Becker, Joy
name: Hick, Paul
name: Hutson, Kate
name: González, Alejandro Trujillo
name: Tweedie, Alison
name: Miller, Terrence
name: Whittington, Richard
name: Robinson, Andrew
Publisher: name: Fisheries Research and Development Corporation
Year: 2017

description: Final report of "Aquatic Animal Health Subprogram: Strategic approaches to identifying pathogens of quarantine concern associated with the importation of ornamental fish" (Project Number: 2014/001).
Control of fungal spoilage in strawberries using crude plant extracts against the fungus Botrytis cinerea
Creators: name: Leite, Ana Rita Zulim
name: Cardoso, Flávia Aparecida Reitz
name: Gardenal, Amanda Correia
name: de Mello, João Carlos Palazzo
name: Marques, Leila Larisa Medeiros
name: Perdoncini, Marcia Regina Ferreira Geraldo
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: Virology

description: The study evaluated the conservation of strawberries treated with crude plant extracts (barbatimão, sibipiruna, guarana, and catuaba) against fungal deterioration and physicochemical characteristics. MIC of 0.125; 0.0156; 0.25 and 0.0312 g/mL were found for barbatimão, sibipiruna, guaraná and catuaba, respectively, against B. cinerea. Treated samples showed no fungal deterioration during 11 days. Analyzes of weight loss, soluble solids, titratable acidity, and pH variation were performed. Sibipiruna showed lower values ​​of mass loss, and the greatest occurred for the catuaba extract. Barbatimão did not change soluble solids and stood out with catuaba in the color parameters L and a*. Small changes in pH were observed with time. Soluble solids maintained values ​​between 6.47 oBrix and 9.90 oBrix for catuaba and sibipiruna extracts at zero and six days. Principal component analysis did not show a strong correlation between the variables. The extracts become alternatives for strawberry conservation, increasing conservation and maintaining physicochemical characteristics.
Gamma Radiolysis of Phenyl-Substituted TODGAs: Part I
Creators: name: Zarzana, Christopher A.
name: McAlpine, Jack
name: Wilden, Andreas
name: Hupert, Michelle
name: Stärk, Andrea
name: Iqbal, Mudassir
name: Verboom, Willem
name: Mincher, Bruce J.
name: Groenewold, Gary S.
name: Modolo, Giuseppe
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: The radiolytic stabilities of three phenylated analogs of N,N,N’,N’-tetraoctyl diglycolamide (TODGA) were investigated: 2-(2-(di-n-octylamino)-2-oxoethoxy)-N,N-di-n-octyl-2-phenylacetamide (PhTODGA), which has a phenyl substituent bound to a central methylene, 2-(2-(di-n-octylamino)-2-oxo-1-phenylethoxy)-N,N-di-n-octylpropanamide (PhMeTODGA), which also contains a methyl substituent bound to the methylene on the other side of the ether moiety, and, 2-(2-N-n-hexyl-N-phenylamino)-2-oxoethoxy)-N-n-hexyl-N-phenylacetamide (DHDPDGA), which has phenyl substituents located on the amide groups instead of the central methylenes. The objective of Part I of this series of papers covers was to evaluate the contribution of the phenyl group to the radiolytic stability of these diglycolamides when irradiated in a) n-dodecane, and b) n-dodecane in the presence of a nitric acid-containing aqueous phase. The results indicate that the presence of the phenyl group decreases the overall radiolytic stability compared to unsubstituted TODGA. However, the results also indicate that the phenyl groups interact with nitric acid in a cooperative fashion that enhances the radiation stability of the phenylated diglycolamide (DGA) derivatives in the presence of a nitric acid-containing aqueous phase compared to irradiation in only n-dodecane. The results are consistent with the hypothesized formation of nitric acid-phenylated DGA complexes in the n-dodecane phase that are significantly more stable with respect to gamma irradiation, compared to the phenylated DGA molecules alone.
OUTCOMES IN PATIENTS WITH DIABETES MELLITUS USING MAIL ORDER AND RETAIL PHARMACY SERVICES: A SYSTEMATIC REVIEW
Creators: name: Eileen Monaghan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Programs to increase use of mail order (MO) pharmacy services are used to control the rising costs of prescription drug services.  
A systemic review was conducted to assess potential benefit of MO pharmacy compared to retail pharmacy in patients with diabetes. A search of PubMed, CINAHL, and Scopus databases from 2010 to January 2020 identified fifty-nine (59) articles.  Eleven studies met criteria for inclusion in the review. 
Eight of nine studies evaluating medication adherence reported greater adherence among MO pharmacy patients.  The weight of evidence suggests the use of MO pharmacy is associated with improved outcomes compared to retail pharmacy. However, the overall quality of the evidence is low.  
Studies employing a standard definition for MO pharmacy users and controlling for patient and system-level factors known to be associated with medication adherence and preference for MO use would provide stronger evidence for a benefit of MO pharmacy.
Additional file 1 of Environmental assessment of cytotoxic drugs in healthcare settings: protocol for a systematic review and meta-analysis
Creators: name: Alawi, Laila Al
name: Elpidoforos S. Soteriades
name: Marilia Silva Paulo
name: Östlundh, Linda
name: Grivna, Michal
name: Maskari, Fatima Al
name: Al-Rifai, Rami H.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Table S1. PRISMA-P (Preferred Reporting Items for Systematic review and Meta-Analysis Protocols) 2015 checklist.
PSSOH Conference
Creators: name: Pejović, Predrag
Publisher: name: Zenodo
Year: 2018
Subjects: free software
open hardware
women in STEM
conference

description: Presentation for the PSSOH Introductory speech held by Prof. Predrag Pejović on behalf of Organizational and Editorial board of the PSSOH 2018 Conference organized by the University of Belgrade - School of Electrical Engineering.
Naringenin biosynthesis and fabrication of naringenin mediated nano silver conjugate for antimicrobial potential
Creators: name: Salunkhe, Jitendra D.
name: Mohite, Bhavana V.
name: Patil, Satish V.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer

description: The development of resistance, instability and high doses are some drawbacks of biologically active natural products. Modification of natural compounds to make it broad spectrum is the standard approach in drug design. This paper sets to modify the naringenin by silver nanoparticle conjugation to enhance its already reported pharmacological activities. The naringenin-nano silver conjugate was synthesized by one-step green synthesis, that is, sunlight exposure confirmed by UV spectroscopy. The biosynthesized naringenin-nanosilver conjugate was tested for antiacanthamoebal and antimicrobial potential. The antibacterial potential was increased by 5.8–6.14 fold against Gram positive bacteria, that is, S. aureus and Bacillus subtilis and 4.5–13.6 fold against Gram negative bacteria, that is, Escherichia coli and Pseudomonas aeruginosa. The standard naringenin-nanosilver conjugate significantly reduced the LC50 values against the Acanthamoeba cells, by, 66% and 36%, as compared to substrate naringin and standard naringenin respectively while biotransformed naringinin-nanosilver conjugate reduced LC50 by 50.56%, compared with biotransformed naringenin. Hence modification of natural product as nanoconjugate is the best practice for improvement as an effective drug.
Breakfast After the Bell: A Nutrition-Based Solution to Improving Education Access & Quality in Cleveland County Schools
Creators: name: Ragan, Kim
name: Fitterer, Amanda
name: Feld, Anna
name: Johnson, Sarah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: This proposal describes a school nutrition program that will improve education access and quality by addressing chronic absenteeism for the secondary students at Cleveland County Schools (CCS). Chronic absenteeism or missing more than 10% of school days, is linked to poor academic performance and serious health issues that persist into adulthood. Nationally, rural schools, like those in Cleveland County, have higher absence rates compared to suburban schools. Breakfast After the Bell (BAB) is an evidence-based program proven to improve school attendance and provides school breakfast through three different, school-dependent models. This program would incorporate an interdisciplinary approach between CCS and the Cleveland County Public Health Department (CCPHD), while focusing on primary stakeholders like students and families. Addressing nutrition and school attendance will result in improved school attendance, graduation rates, educational attainment, and health outcomes.
Community Adaptation of the New Hope Project to Improve Economic Stability in Cleveland County, NC
Creators: name: Furtick, Joseph
name: Dickstein, Anna
name: Oldham, Laura
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Financial stability allows families access to safe housing, healthy foods, and other necessities, engage fully in their communities, and plan for the future (2019). This project focuses on addressing economic stability in Cleveland County, North Carolina. Children living in poverty are less likely to eat healthy foods, experience higher rates of neglect and abuse, low academic achievement, obesity, behavioral problems, and other issues which may follow children from their youth into adulthood (Haynie, 2014). The program, administered through the Cleveland County Health Department, will seek to increase wages in families of color by providing them with paid job skills training and higher wage job placement through an already existing and successful job training program. This initiative will achieve greater equity in Cleveland County and lessen the already exacerbated health disparities that exist in the community by allowing program participants to contribute more to the Cleveland County community and economy.
Inferring coarse-grain histone-DNA interaction potentials from high-resolution structures of the nucleosome
Creators: name: Meyer, Sam
name: Everaers, Ralf
Publisher: name: arXiv
Year: 2014
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Biomolecules (q-bio.BM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: The histone-DNA interaction in the nucleosome is a fundamental mechanism of genomic compaction and regulation, which remains largely unkown despite a growing structural knowledge of the complex. Here, we propose a framework for the extraction of a nanoscale histone-DNA force-field from a collection of high-resolution structures, which may be adapted to a larger class of protein-DNA complexes. We apply the procedure on a large crystallographic database extended by snapshots from molecular dynamics simulations. The comparison of the structural models first shows that, at the sites of histone-DNA contact, the DNA base-pairs are locally shifted outwards, consistent with locally repulsive forces exerted by the histones. In a second step, we show that the various force profiles of the analyzed structures derive locally from a unique, sequence-independent, quadratic repulsive force field, while the sequence preferences are entirely due to the internal DNA mechanics. We thus obtain the first knowledge-derived nanoscale potential for the histone-DNA interaction in the nucleosome. The conformations obtained by relaxation of nucleosomal DNA with high-affinity sequences in this potential accurately reproduce experimental values of binding preferences. We finally address the more generic binding mechanisms relevant to the 80% genomic sequences incorporated in nucleosomes, by computing the conformation of nucleosomal DNA with sequence-averaged properties. This conformation is found to differ from those found in crystals, and the analysis suggests that repulsive histone forces are related to a local stretch tension in nucleosomal DNA, mostly between successive contact points. This tension could play a role in the stability of the complex.
description: 18 pages, 11 figures. Special issue article
Signatures of Horndeski gravity on the Dark Matter Bispectrum
Creators: name: Bellini, Emilio
name: Jimenez, Raul
name: Verde, Licia
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a detailed study of second-order matter perturbations for the general Horn- deski class of models. Being the most general scalar-tensor theory having second-order equations of motion, it includes many known gravity and dark energy theories and General Relativity with a cosmological constant as a specific case. This enables us to estimate the leading order dark matter bispectrum generated at late-times by gravitational instability. We parametrize the evolution of the first and second-order equations of motion as proposed by Bellini and Sawicki (2014), where the free functions of the theory are assumed to be proportional to the dark energy density. We show that it is unnatural to have large 10% ( 1%) deviations of the bispectrum introducing even larger ~ 30% (~ 5%) deviations in the linear growth rate. Considering that measurements of the linear growth rate have much higher signal-to-noise than bispectrum measurements, this indicates that for Horndeski models which reproduce the expansion history and the linear growth rate as predicted by GR the dark matter bispectrum kernel can be effectively modelled as the standard GR one. On the other hand, an observation of a large bispectrum deviation that can not be explained in terms of bias would imply either that the evolution of perturbations is strongly different than the evolution predicted by GR or that the theory of gravity is exotic (e.g., breaks the weak equivalence principle) and/or fine-tuned.
description: 14 pages, 5 figures. Matches the version accepted by JCAP. Minor changes, Figure 4 replaced. References added
POLICY AND PROGRAMMATIC OPPORTUNITIES TO IMPROVE ACCESS TO NUTRITIOUS FOODS AMONG CHILDREN IN CLEVELAND COUNTY
Creators: name: Gabriella Herter
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: The social and community context in which an individual lives is an essential social determinant of health (SDoH) that has been shown to have wide-ranging effects on quality of life and health. The social and community context interacts reciprocally with food insecurity (FI), making it essential to address FI. Thousands of children under the age of 18 are impacted by FI in Cleveland County, which has detrimental impacts on this vulnerable population’s social, emotional, and physical well-being. The Cleveland County Commissioners can appropriate funds to create a Meal Express Summer Food Program (MESFP) and establish the Mobile Meals for Children (MMC) program to address childhood FI. The MESFP will deliver federally funded summer meals, while the MMC program will deliver groceries to food-insecure households Both opportunities expand on evidence-based activities that will provide services and support to the community's children who need it most.
Bericht über die 5. Internationale München-Freising Konferenz „Etappen der Globalisierung in christentumsgeschichtlicher Perspektive / Phases of Globalization in the History of Christianity“
Creators: name: Burlacioiu, Ciprian
Publisher: name: Mitteilungen zur Kirchlichen Zeitgeschichte
Year: 2022

description: Mitteilungen zur Kirchlichen Zeitgeschichte, Bd. 5 (2011)
MOESM1 of Long-term monitoring reveals invariant clutch size and unequal reproductive costs between sexes in a subtropical lacertid lizard
Creators: name: Jhan-Wei Lin
name: Ying-Rong Chen
name: Tsui-Wen Li
name: Pei-Jen Shaner
name: Lin, Si-Min
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Figure S1. Monthly capture record of (a) adults; (b) juveniles; (c) recapture rates of all individuals; and (d) male/female composition (green/red) from May 2006 to August 2013. Figure S2. Sexual size dimorphism of Takydromus viridipunctatus.
The second PSSOH: Editorial board perspective
Creators: name: Cvetanović, Miloš
Publisher: name: Zenodo
Year: 2020
Subjects: free software
open hardware
women in STEM
conferece

description: Slides for the second PSSOH conference during Opening ceremony held by Assoc. Prof. Miloš Cvetanović on behalf of Organizational and Editorial board of the PSSOH 2019 Conference organized by the University of Belgrade - School of Electrical Engineering.
A novel anti-hyperglycemic sulfated pyruvylated polysaccharide from marine macroalga Hydropuntia edulis
Creators: name: Thambi, Anjaly
name: Chakraborty, Kajal
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Dipeptidyl peptidase is a crucial enzyme that regulates glucose metabolism by degrading incretins, such as glucagon-like-peptide-1, thereby reducing insulin secretion from the pancreatic β-cells. Consequently, dipeptidyl peptidase-IV inhibitors are an important remedial approach to moderate the hyperglycemic pathophysiology. A pyruvylated polysaccharide characterized as [→3)-4,6-O-(1-carboxyethylidene)-β-D-galp-(2SO3−)-(1→4)-3,6-α-L-AnGalp-(2OMe)-(1→], isolated from the marine macroalga Hydropuntia edulis, showed attenuation potential against dipeptidyl peptidase-IV (IC50 4.44 μM). The structure was elucidated using mass and one/two-dimensional nuclear magnetic resonance spectroscopic analyses of hydrolyzed polysaccharide besides glycosidic linkages obtained from partially methylated alditol acetate derivative. The isolated polysaccharide also revealed potential anti-carbolytic properties against α-amylase/α-glucosidase (IC50 45–47 μM). The results proved the candidacy of pyruvylated polysaccharide isolated from H. edulis as a potential therapeutic lead against hyperglycemia.
Effect of salicylic acid elicitor on antioxidant potential and chemical composition of in vitro raised plants of Berberis asiatica Roxb. ex DC.
Creators: name: Dobhal, Preeti
name: Agnihotri, Saumya
name: Ashfaqullah, Sayyed
name: Tamta, Sushma
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: The present study for the first time investigated the effects of Salicylic acid (SA) (50, 100 and 200 mg/L) on in vitro growth and antioxidant capacity of Berberis asiatica. SA significantly enhanced in vitro shoot multiplication at 100 mg/L concentration. The result showed highest significant increase in antioxidant activity by 50 mg/L SA elicited plantlets in terms of DPPH (2,2-Di-phenyl-1-picryl-hydrazyl) free radical scavenging activity (IC50 32.42 ± 0.51), Ferric Reducing Antioxidant Activity (292.73 ± 2.09 mg AAE/g dw) and Metal Chelating Activity (IC50 13.18 ± 0.52). The Gas Chromatography–Mass Spectrometry (GC–MS) profiling revealed presence of 46, 38, 34 and 29 phytochemicals in control, SA1, SA2 and SA3 methanolic extracts respectively. Among the identified compounds, eight compounds, 4H-Pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl; 1,3,4,5-tetrahydroxy-cyclohexanecarboxylic acid; 3,7,11,15-Tetramethyl-2-hexadecen-1-ol (and Phytol); hexadecanoic acid, methyl ester; 9,12-Octadecadienoic acid (Z,Z)-,methyl ester; di-n-octyl phthalate; stigmast-5-en-3-ol,(3.beta.)- or ß- sitosterol; and squalene were previously known for antioxidant potential.
Using Cooking Matters Nutrition Intervention Program to Address Healthcare Quality and Access for Black Adults with Cardiovascular Disease in Cleveland County, North Carolina
Creators: name: Abrego, Marcela
name: Berkowitz, Samantha
name: Mohiuddin, Hina
name: Coppage, Racheal
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Our team aims to implement the Cooking Matters program to address rates of cardiovascular disease (CVD) for black adults ages 40 to 64 in Cleveland County, North Carolina. In Cleveland County, the leading cause of death is diseases of the heart, with a death rate of 254.7 per 100,000, which exceeds the state rate of 180.9 per 100,000 (Cleveland County, 2019). Cooking Matters will address CVD by focusing on the role nutrition plays in preventing and managing CVD. The Cooking Matters program was chosen mainly because it fit the community’s request for more affordable health services and nutrition education (“Cleveland County 2019 Community Health Assessment,” 2019). Our team will partner with community organizations to deliver a program that focuses on budgeting, accessing, and preparing meals that are heart-healthy. A prospective cohort study design will be used to evaluate the implementation of the Cooking Matters program in Cleveland County, North Carolina.
Green-based methods to obtain bioactive compounds from Ilex guayusa Loes. using polar solvent
Creators: name: Cadena-Carrera, Santiago
name: Tramontin, Deise Parolo
name: Jacques, Rosângela
name: Scapin, Enelise
name: Müller, José Miguel
name: Hense, Haiko
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: Many biological activities have been reported for the Ilex genus. However, few studies in the literature have reported on guayusa. To address this gap in our knowledge, chemical analysis of guayusa leaves was made. Extracts were obtained by applying Soxhlet, maceration, supercritical CO2 and pressurised liquid extraction techniques, using water and ethanol as solvent/cosolvent. Extracts were evaluated for their phenolic content and antioxidant capacity. The chemical profile was obtained from HPLC. In raw guayusa leaves were identified caffeine (2.27 ± 0.05%), protein (15.31 ± 0.07%) and lipids (11.81 ± 0.14%). Extracts presented the highest phenolic content (156.56 ± 1.32 mg GAE g−1) and the best antioxidant activity (EC50= 61.85 ± 0.21 µg mL−1) when water was used as solvent/cosolvent. Through HPLC, three main substances were determined and quantified in the extracts: caffeine, theobromine and 5-caffeoylquinic acid. Based on these results, guayusa may be considered a natural source of compounds with potential application in the food and pharmaceutical industries.