cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ASSESSMENT OF FACTORS INFLUENCING WILLINGNESS AND UTILIZATION OF VCT AMONG PREGNANT WOMEN IN DESSIE TOWN
Creators: name: ALEMNESH TEKLEBERHAN (Bsc)
Publisher: name: Zenodo
Year: 2007

description: Background-: HIV has spread throughout the world causing untold suffering and death and creating profound development challenges. Worldwide African women are the group most severely affected by the epidemic. Women who are infected by HIV are infecting their infants in turn. Mother to child transmission is the most common cause of HIV/AIDS in children less than 15 years of age. Mother to child transmission can occur during pregnancy, labor and breast-feeding. However the risk of MTCT can be lowered significantly through comprehensive reproductive health services which include voluntary counseling and testing for pregnant women, Anti-retroviral prophylaxis and breast feeding counseling.
Improving usability and sustainability for NumPy and OpenBLAS
Creators: name: Mendonça, Melissa Weber
Publisher: name: figshare
Year: 2020
Subjects: subject: 80306 Open Software
subject: FOS: Computer and information sciences

description: We aim to improve the robustness and usability of NumPy, continuing to work in documentation and community building, modernize its integration with Fortran tools via numpy.f2py and ensure the sustainability of both NumPy and OpenBLAS.
A Pattern based methodology for evolution management in business process reuse
Creators: name: Sbai, Hanae
name: Fredj, Mounia
name: Kjiri, Laila
Publisher: name: arXiv
Year: 2014
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Today, there are Process-Aware Information Systems (PAIS) with a set of business process models which vary over time to meet the new requirements. In a competitive environment, the key challenge of enterprises is to reduce the cost and time of process design and application development. For this purpose, research on reuse in business process management have introduced the concept of configurable process models which attempts to manage business process variability, by integrating a set of process variants in a single model. In this context, many research works were interested in creating and elaborating configurable process models. However, this has become insufficient since the configurable process model should itself evolve to add new variations. In turn, this requires a comprehensive support for managing the evolution of configurable process models. In this paper, we present a complete pattern based methodology for managing the evolution of configurable process models in terms of activities, data and resources. Our objective is to propose a process patterns system for guiding designers in modeling and evolving configurable process models. Furthermore, our process patterns system will be used for an automated support so as to manage the evolution of configurable process models.
description: 10 pages
The origins and concentrations of water, carbon, nitrogen and noble gases on Earth
Creators: name: Marty, Bernard
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The isotopic compositions of terrestrial hydrogen and nitrogen are clearly different from those of the nebular gas from which the solar system formed, and also differ from most of cometary values. Terrestrial N and H isotopic compositions are in the range of values characterizing primitive meteorites, which suggests that water, nitrogen, and other volatile elements on Earth originated from a cosmochemical reservoir that also sourced the parent bodies of primitive meteorites. Remnants of the proto-solar nebula (PSN) are still present in the mantle, presumably signing the sequestration of PSN gas at an early stage of planetary growth. The contribution of cometary volatiles appears limited to a few percents at most of the total volatile inventory of the Earth. The isotope signatures of H, N, Ne and Ar can be explained by mixing between two end-members of solar and chondritic compositions, respectively, and do not require isotopic fractionation during hydrodynamic escape of an early atmosphere. The terrestrial inventory of 40Ar (produced by the decay of 40K throughout the Earth's history) suggests that a significant fraction of radiogenic argon may be still trapped in the silicate Earth. By normalizing other volatile element abundances to this isotope, it is proposed that the Earth is not as volatile-poor as previously thought. Our planet may indeed contain up to ~3000 ppm water (preferred range : 1000-3000 ppm), and up to ~500 ppm C, both largely sequestrated in the solid Earth. This volatile content is equivalent to a ~2 (+/-1) % contribution of carbonaceous chondrite (CI-CM) material to a dry proto-Earth, which is higher than the contribution of chondritic material advocated to account for the platinum group element budget of the mantle. Such a (relatively) high contribution of volatile-rich matter is consistent with the accretion of a few wet planetesimals during Earth accretion.
A Distributed Reception Architecture for Low-Power Wide-Area Networking
Creators: name: Adwait Dongare
Publisher: name: Carnegie Mellon University
Year: 2020
Subjects: Computer Engineering

description: A large number of pervasive sensors will manage and optimize the infrastructure in future smart cities.Ideally, we will be able to sense everything from bridges, buildings and firetrucks, all the way to trash cans,bicycles and street lights. The growing field of low-power wide-area networking (LPWAN) looks at the challenge of wirelessly communicating with a large number of low-power, simple devices over long periods of time. These city-wide networks need to provide two important functions: extracting data from sensors and keeping track of where they are located. We explore the capabilities of these networks by deploying and evaluating our own OpenChirp LPWAN network around the Carnegie Mellon University campus. Though promising, these networks still suffer from problems of coverage, conservation of device battery and the lackof an ability to accurately localize devices. This thesis will explore the design space and potential of usingtightly coordinated distributed gateway receivers to efficiently decode data, as well as to locate the transmittingdevices. It is challenging to develop distributed radio systems that utilize physical layer signals withoutoverwhelming the backhaul network. We first introduce a coherent combining system, called Charm, thatimproves network coverage, data rates and battery life of deployed devices by selectively collating receptionsfrom multiple receiving gateways. In an indoor environment with high multipath, accurate time synchronizationat nanosecond accuracies is challenging, but plays an important role in enabling both localization and coherent combining. Thus, we develop a time synchronization platform, called Pulsar, for nanosecond-scale synchronization of radios. Next, we show how we can extend our distributed reception system with time synchronized receivers to improve device localization through the use of time-difference-of-arrival features inchallenging urban environments. With multiple receivers that are accurately time synchronized, we see the potential to significantly improve LPWAN performance and effectively localize transmitting devices.
Scale-free phase field theory of dislocations
Creators: name: Groma, Istvan
name: Vandrus, Zoltan
name: Ispanovity, Peter Dusan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: According to recent experimental and numerical investigations if the characteristic size of a specimen is in the submicron size regime several new interesting phenomena emerge during the deformation of the samples. Since in such a systems the boundaries play a crucial role, to model the plastic response of submicron sized crystals it is crucial to determine the dislocation distribution near the boundaries. In this paper a phase field type of continuum theory of the time evolution of an ensemble of parallel edge dislocations with identical Burgers vectors, corresponding to the dislocation geometry near boundaries, is presented. Since the dislocation-dislocation interaction is scale free ($1/r$), apart from the average dislocation spacing the theory cannot contain any length scale parameter. As shown, the continuum theory suggested is able to recover the dislocation distribution near boundaries obtained by discrete dislocation dynamics simulations.
Magnetic structure map for face-centered tetragonal iron: appearance of a new collinear spin structure
Creators: name: Reith, D.
name: Podloucky, R.
name: Marsman, M.
name: Bedolla-Velazquez, P. O.
name: Mohn, P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: For face-centered cubic (fcc) and tetragonal (fct) iron a large number of magnetic configurations as a function of crystal structural parameters were studied by means of density functional theory. The stability of magnetic structures was defined by the magnetic re-orientation energy $Δ{E}^i_\text{reor}$ as the difference of the total energy of configuration $i$ and that of the fcc ferromagnetic state. The Cluster Expansion technique was applied to several volumes deriving $Δ{E}_\text{reor}$ for more than 90.000 collinear spin structures for each volume. A variety of structures with promisingly low $Δ{E}_\text{reor}$ were tetragonally distorted according to a two-dimensional mesh defined by volume per atom and $c/a$ ratio of the distortion. At each of the points on this mesh $ΔE_\text{reor}$ of all collinear structure were compared to results for non-collinear spin spirals (SS) which were calculated for a grid of propagation directions. The lowest $Δ{E}_\text{reor}$ of all investigated spin structures then defined the magnetic structure map spanned by volume per atom and $c/a$ ratio. Three local minima were identified and for each of the minima SS were calculated on a fine grid of propagation vectors. For the volume per atom of 10.6 Å$^3$ and the distortion range $0.94 \le c/a \le 1.01$ we found a new, surprisingly simple collinear spin structure with four atoms per fct unit cell to be the most stable one. This structure was called AFM/NM because it consists of two atoms with anti-ferromagnetically ordered local moments of $\pm 1.8 μ_\text{B}$ and of two nonmagnetic atoms with zero local moment. It seems that the newly detected AFM/NM structure explains a variety of puzzling experimental results.
Long Range Coupling between Metallic Nanocavities
Creators: name: Salomon, Adi
name: Prior, Yehiam
name: Fedoruk, Michael
name: Feldmann, Jochen
name: Kolkowski, Radoslaw
name: Zyss, Joseph
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: When two or more metallic nanoparticles are in close proximity, their plasmonic modes may interact through the near field, leading to additional resonances of the coupled system or to shifts of their resonant frequencies. This process is analogous to atom-hybridization, as had been proposed by Gersten and Nitzan and modeled by Nordlander et al. The coupling between plasmonic modes can be in-phase (symmetric) or out-of-phase (anti-symmetric), reflecting correspondingly, the "bonding" and "anti-bonding" nature of such configurations. Since the incoming light redistributes the charge distribution around the metallic nanoparticles, its polarization features play a major role in the nonlinear optical probing of the energy-level landscape upon hybridization. Thus, controlling the nature of coupling between metallic nanostructures is of a great importance as it enables tuning their spectral responses leading to novel devices which may surpass the diffraction limit.
description: arXiv admin note: text overlap with arXiv:1303.0492
Negative-U properties for substitutional Au in Si
Creators: name: Corsetti, Fabiano
name: Mostofi, Arash A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The isolated substitutional gold impurity in bulk silicon is studied in detail using electronic structure calculations based on density-functional theory. The defect system is found to be a non-spin-polarized negative-U centre, thus providing a simple solution to the long-standing debate over the electron paramagnetic resonance signal for gold in silicon. There is an excellent agreement (within 0.03 eV) between the well-established experimental donor and acceptor levels and the predicted stable charge state transition levels, allowing for the unambiguous assignment of the two experimental levels to the (1+/1-) and (1-/3-) transitions, respectively, in contrast to previously held assumptions about the system.
description: 6 pages, 5 figures
Nitrogen Isotopic Composition and Density of the Archean Atmosphere
Creators: name: Marty, Bernard
name: Zimmermann, Laurent
name: Pujol, Magali
name: Burgess, Ray
name: Philippot, Pascal
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Understanding the atmosphere's composition during the Archean eon is a fundamental issue to unravel ancient environmental conditions. We show from the analysis of nitrogen and argon isotopes in fluid inclusions trapped in 3.0-3.5 Ga hydrothermal quartz that the PN2 of the Archean atmosphere was lower than 1.1 bar, possibly as low as 0.5 bar, and had a nitrogen isotopic composition comparable to the present-day one. These results imply that dinitrogen did not play a significant role in the thermal budget of the ancient Earth and that the Archean PCO2 was probably lower than 0.7 bar.
Extended Bose-Hubbard model with pair tunneling: spontaneous symmetry breaking, effective ground state and fragmentation
Creators: name: Zhu, Qizhong
name: Zhang, Qi
name: Wu, Biao
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: The extended Bose-Hubbard model for a double-well potential with pair tunneling is studied through both exact diagonalization and mean field theory (MFT). When pair tunneling is strong enough, the ground state wavefunction predicted by the MFT is complex and doubly degenerate while the quantum ground state wavefunction is always real and unique. The time reversal symmetry is spontaneously broken when the system transfers from the quantum ground state into one of the mean field ground states upon a small perturbation. As the gap between the lowest two levels decreases exponentially with particle number, the required perturbation inducing the spontaneous symmetry breaking (SSB) is infinitesimal for particle number of typical cold atom systems. The quantum ground state is further analyzed with the Penrose-Onsager criterion, and is found to be a fragmented condensate. The state also develops the pair correlation and has non-vanishing pair order parameter instead of the conventional single particle order parameter. When this model is generalized to optical lattice, a pair superfluid can be generated. The mean field ground state can be regarded as effective ground state in this simple model. The detailed computation for this model enables us to offer an in-depth discussion of the relation between SSB and effective ground state, giving a glimpse on how nonlinearity arises in the SSB of a quantum system.
description: 6 pages, 6 figures
Probing Long-Range Intensity Correlations inside Disordered Photonic Nanostructures
Creators: name: Sarma, Raktim
name: Yamilov, Alexey
name: Neupane, Pauf
name: Shapiro, Boris
name: Cao, Hui
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We report direct observation of the development of long-range spatial intensity correlations and the growth of intensity fluctuations inside the random media. We fabricated quasi-two-dimensional disordered photonic structures and probed the light transport from a third dimension. Good agreements between experiment and theory are obtained. We were able to manipulate the long-range intensity correlations and intensity fluctuations inside the disordered waveguides by simply varying the waveguide geometry.
description: 5 figures
title: 1,4-Dipolar Cycloadditions of Cyclopent[cd]azulene
Creators: name: Diehl, Herbert
name: Hafner, Klaus
Publisher: name: Wiley
Year: 2022

description: Cycloadditions of nonbenzenoid carbo- and heterocyclic conjugated π-electron systems with suitable reactants provide a facile entry to ring systems that were hitherto difficult to prepare, if at all[¹]. For instance, cyclopent[cd]azulene (1)I²] which is now readily accessible reacts with dimethyl acetylenedicarboxylate even at room temperature to give 75 % of the 1:1 adduct (2).
Delta chain with ferromagnetic and antiferromagnetic interactions at the critical point
Creators: name: Krivnov, V. Ya.
name: Dmitriev, D. V.
name: Nishimoto, S.
name: Drechsler, S. -L.
name: Richter, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We investigate the spin-1/2 Heisenberg model on the delta chain (sawtooth chain) with ferromagnetic nearest-neighbor and antiferromagnetic next-neighbor interactions. For a special ratio between these interactions there is a class of exact ground states formed by localized magnons and the ground state is macroscopically degenerate with a large residual entropy per spin $s_0=\frac{1}{2}\ln 2$. An important feature of this model is a sharp decrease of the gaps for excited states with an increase of the number of magnons. These excitations give an essential contribution to the low-temperature thermodynamics. The behavior of the considered model is compared with that of the delta chain with both antiferromagnetic interactions.
description: 24 pages, 10 figures
"TNOs are Cool": A survey of the trans-Neptunian region X. Analysis of classical Kuiper belt objects from Herschel and Spitzer observations
Creators: name: Vilenius, E.
name: Kiss, C.
name: Müller, T.
name: Mommert, M.
name: Santos-Sanz, P.
name: Pál, A.
name: Stansberry, J.
name: Mueller, M.
name: Peixinho, N.
name: Lellouch, E.
name: Fornasier, S.
name: Delsanti, A.
name: Thirouin, A.
name: Ortiz, J. L.
name: Duffard, R.
name: Perna, D.
name: Henry, F.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The classical Kuiper belt contains objects both from a low-inclination, presumably primordial, distribution and from a high-inclination dynamically excited population. Based on a sample of classical TNOs with observations at thermal wavelengths we determine radiometric sizes, geometric albedos and thermal beaming factors as well as study sample properties of dynamically hot and cold classicals. Observations near the thermal peak of TNOs using infra-red space telescopes are combined with optical magnitudes using the radiometric technique with near-Earth asteroid thermal model (NEATM). We have determined three-band flux densities from Herschel/PACS observations at 70.0, 100.0 and 160.0 $μ$m and Spitzer/MIPS at 23.68 and 71.42 $μ$m when available. We have analysed 18 classical TNOs with previously unpublished data and re-analysed previously published targets with updated data reduction to determine their sizes and geometric albedos as well as beaming factors when data quality allows. We have combined these samples with classical TNOs with radiometric results in the literature for the analysis of sample properties of a total of 44 objects. We find a median geometric albedo for cold classical TNOs of 0.14 and for dynamically hot classical TNOs, excluding the Haumea family and dwarf planets, 0.085. We have determined the bulk densities of Borasisi-Pabu (2.1 g/cm^3), Varda-Ilmare (1.25 g/cm^3) and 2001 QC298 (1.14 g/cm^3) as well as updated previous density estimates of four targets. We have determined the slope parameter of the debiased cumulative size distribution of dynamically hot classical TNOs as q=2.3 +- 0.1 in the diameter range 100
description: 22 pages, 7 figures Accepted to be published in Astronomy and Astrophysics
Intrinsic weak derivatives and Sobolev spaces between manifolds
Creators: name: Convent, Alexandra
name: Van Schaftingen, Jean
Publisher: name: arXiv
Year: 2013
Subjects: subject: Functional Analysis (math.FA)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 58D15 (46E35, 46T10, 53C25, 58E20)

description: We define the notion of colocally weakly differentiable maps from a manifold $M$ to a manifold $N$. If $p \ge 1$ and $M$ and $N$ are endowed with a Riemannian metric, this allows us to define intrinsically the homogeneous Sobolev space $\dot{W}^{1, p} (M, N)$. This new definition is equivalent with the definition by embedding in the Euclidean space and with the definition of Sobolev maps into a metric space. The colocal weak derivative is an approximate derivative. The colocal weak differentiability is stable under the suitable weak convergence. The Sobolev spaces can be endowed with various intrinsinc distances that induce the same topology and for which the space is complete.
description: 28 pages
Explosion and nucleosynthesis of low redshift pair instability supernovae
Creators: name: Kozyreva, Alexandra
name: Yoon, Sung-Chul
name: Langer, Norbert
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Both recent observations and stellar evolution models suggest that pair-instability supernovae (PISNe) could occur in the local Universe, at metallicities below Z_Sun/3. Previous PISN models were mostly produced at very low metallicities in the context of the early Universe. We present new PISNe models at a metallicity of Z=0.001, which are relevant for the local Universe. We take the self-consistent stellar evolutionary models of pair-instability progenitors with initial masses of 150 and 250 solar masses at metallicity of Z=0.001 by Langer et al. (2007) and follow the evolution of these models through the supernova explosions, using a hydrodynamics stellar evolution code with an extensive nuclear network including 200 isotopes. Both models explode as PISNe without leaving a compact stellar remnant. Our models produce a nucleosynthetic pattern that is generally similar to that of Population III PISN models, which is mainly characterized by the production of large amounts of alpha-elements and a strong deficiency of the odd-charged elements. However, the odd-even effect in our models is significantly weaker than that found in Population III models. The comparison with the nucleosynthetic yields from core-collapse supernovae at a similar metallicity (Z=0.002) indicates that PISNe could have strongly influenced the chemical evolution below Z=0.002, assuming a standard initial mass function. The odd-even effect is predicted to be most prominent for the intermediate mass elements between silicon and calcium. With future observations of chemical abundances in Population II stars, our result can be used to constrain the number of PISNe that occurred during the past evolution of our Galaxy.
description: 10 pages, 13 figures, 3 tables. Accepted by Astronomy & Astrophysics
Ioniorhynchus Magrini, Meoli & Abbazzi 2005
Creators: name: Hlaváč, Peter
name: Skuhrovec, Jiří
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Ioniorhynchus

description: Ioniorhynchus Magrini, Meoli & Abbazzi, 2005
 Ioniorhynchus Magrini, Meoli & Abbazzi, 2005. Type species: Ioniorhynchus doriae (A. & F. Solari, 1903), original designation
 Ioniorhynchus Magrini, Meoli & Abbazzi: Magrini et al. 2011
 Otiorhynchus (subg. Ioniorhynchus) Magrini, Meoli & Abbazzi: Osella & Zuppa, 2006; Osella 2008; Magnano & Alonso- Zarazaga, 2013.
 The genus Ioniorhynchus can be recognized within the large Otiorhynchus complex of genera (Magnano 1998) by the elongate, slender, shining body, pronotum longer than wide, elytra about as wide as pronotum, eyes completely absent, rostrum longer than wide, antennae long and slender, epipleura curved at the level of hind coxae, base of elytra straight, closely fitting the base of pronotum, all femora dentate, aedeagus long and slender, hooked and curved at apex, S-shaped in lateral view.
description: Published as part of Hlaváč, Peter & Skuhrovec, Jiří, 2016, Endogean and cavernicolous Coleoptera of the Balkans. XV. A new species of the genus Ioniorhynchus Magrini, Meoli & Abbazzi, 2005 (Coleoptera: Curculionidae: Entiminae) from Greece, pp. 129-138 in Zootaxa 4092 (1) on page 130, DOI: 10.11646/zootaxa.4092.1.8, http://zenodo.org/record/258901
Safety and effectiveness of empagliflozin in Japanese patients with type 2 diabetes: final results of a 3-year post-marketing surveillance study
Creators: name: Kaku, Kohei
name: Yamamoto, Kazuhiro
name: Fukushima, Yumiko
name: Lliev, Hristo
name: Yasui, Atsutaka
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Empagliflozin, a sodium-glucose co-transporter-2 inhibitor, was licensed for treating type 2 diabetes (T2D) in Japan and elsewhere in recent years. We conducted a post-marketing surveillance study of empagliflozin in Japan. This was a 3-year, prospective, multicenter, observational study of the safety and effectiveness of empagliflozin in T2D patients in Japanese clinical practice who had not previously received this medication. The primary endpoint was the incidence of adverse drug reactions (ADRs). Of 8145 patients enrolled from 1103 sites, 7931 received ≥1 dose of empagliflozin. Mean age was 58.7 years (10.5% aged ≥75), glycated hemoglobin (HbA1c) 8.0%, body mass index 28.1 kg/m2 (<20 kg/m2 in 2.1%); 63.0% were male and most had comorbidities (renal impairment in ~62%). Median treatment duration was 36.5 months. ADRs occurred in 1024 (12.91%) patients overall (serious ADRs in 2.09%) and 120 patients aged ≥75 years (14.46%). ADRs of special interest included hypoglycemia (0.44% of patients), urinary tract infections (1.07%), genital infections (0.66%), volume depletion (0.50%), diabetic ketoacidosis (0%), and lower limb amputation (0.04%). Overall mean change in HbA1c from baseline was –0.75%. Empagliflozin is effective and generally well tolerated in Japanese patients, and ADRs are consistent with its known safety profile.
Long-term safety and effectiveness of linagliptin by baseline body mass index in Japanese patients with type 2 diabetes: a 3-year post-marketing surveillance study
Creators: name: Yabe, Daisuke
name: Yamamoto, Fumiko
name: Lund, Søren S.
name: Okamura, Tomoo
name: Kadowaki, Takashi
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: A recent 3-year post-marketing surveillance (PMS) study reaffirmed the safety and effectiveness of linagliptin in linagliptin-naïve Japanese patients with type 2 diabetes (T2D). We present further analyses from this study by body mass index (BMI). Safety and effectiveness were assessed across BMI subgroups (<25, 25 to <30, and ≥30 kg/m2). Data were available for 876, 566, and 201 patients in the BMI subgroups, respectively. Incidence of adverse drug reactions [ADR] with linagliptin was 11.42%, 11.31%, 10.45%, respectively. The most common ADR of special interest was hepatic disorders (n [%]: 6 [0.68], 7 [1.24], and 3 [1.49], respectively). Additional use of glucose-lowering drugs (GLDs) increased with BMI (15.0%, 19.1%, 24.4% of patients; P < 0.001). In the overall population, HbA1c change (adjusted mean %±SE) until week 156 was –0.71±0.04, –0.68±0.04 and –0.74±0.09. In patients receiving linagliptin with no additional GLDs, HbA1c changes were –0.58%±0.04, –0.62%±0.04, and –0.77%±0.11. In this study of linagliptin in Japanese patients with T2D, across BMI subgroups no new safety concerns were observed. The proportion of patients with additional GLD use increased with baseline BMI. Decreases in HbA1c were observed in all subgroups, including in patients with no additional GLD use. NCT01650259
Long-term safety and effectiveness of linagliptin by baseline body mass index in Japanese patients with type 2 diabetes: a 3-year post-marketing surveillance study
Creators: name: Yabe, Daisuke
name: Yamamoto, Fumiko
name: Lund, Søren S.
name: Okamura, Tomoo
name: Kadowaki, Takashi
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: A recent 3-year post-marketing surveillance (PMS) study reaffirmed the safety and effectiveness of linagliptin in linagliptin-naïve Japanese patients with type 2 diabetes (T2D). We present further analyses from this study by body mass index (BMI). Safety and effectiveness were assessed across BMI subgroups (<25, 25 to <30, and ≥30 kg/m2). Data were available for 876, 566, and 201 patients in the BMI subgroups, respectively. Incidence of adverse drug reactions [ADR] with linagliptin was 11.42%, 11.31%, 10.45%, respectively. The most common ADR of special interest was hepatic disorders (n [%]: 6 [0.68], 7 [1.24] and 3 [1.49], respectively). Additional use of glucose-lowering drugs (GLDs) increased with BMI (15.0%, 19.1%, 24.4% of patients; P < 0.001). In the overall population, a sustained decrease in HbA1c was observed in all BMI subgroups. In patients receiving linagliptin with no additional GLDs, changes in HbA1c were –0.58%±0.04, –0.62%±0.04, and –0.77%±0.11. In this study of linagliptin in Japanese patients with T2D, across BMI subgroups no new safety concerns were observed. The proportion of patients with additional GLD use increased with baseline BMI. Decreases in HbA1c were observed in all subgroups, including in patients with no additional GLD use. NCT01650259
Strangeness enhancement at the hadronic chemical freeze-out
Creators: name: Sagun, V. V.
name: Oliinychenko, D. R.
name: Bugaev, K. A.
name: Cleymans, J.
name: Ivanytskyi, A. I.
name: Mishustin, I. N.
name: Nikonov, E. G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The chemical freeze-out of hadrons created in the high energy nuclear collisions is studied within the realistic version of the hadron resonance gas model. The chemical non-equilibrium of strange particles is accounted via the usual $γ_{s}$ factor which gives us an opportunity to perform a high quality fit with $χ^2/dof \simeq 63.5/55 \simeq 1.15$ of the hadronic multiplicity ratios measured from the low AGS to the highest RHIC energies. In contrast to previous findings, at low energies we observe the strangeness enhancement instead of a suppression. In addition, the performed $γ_{s}$ fit allows us to achieve the highest quality of the Strangeness Horn description with $χ^2/dof=3.3/14$. For the first time the top point of the Strangeness Horn is perfectly reproduced, which makes our theoretical horn as sharp as an experimental one. However, the $γ_{s}$ fit approach does not sizably improve the description of the multi-strange baryons and antibaryons. Therefore, an apparent deviation of multi-strange baryons and antibaryons from chemical equilibrium requires further explanation.
description: 7 pages, 12 figures
Globular clusters of NGC 3115 in the near-infrared. Demonstrating the correctness of two opposing scenarios
Creators: name: Cantiello, Michele
name: Blakeslee, John P.
name: Raimondo, Gabriella
name: Chies-Santos, Ana L.
name: Jennings, Zachary G.
name: Norris, Mark A.
name: Kuntschner, Harald
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We combined new near-infrared VLT/HAWK-I data of the globular clusters (GCs) in the isolated edge-on S0 galaxy NGC 3115 with optical and spectroscopic ones taken from the literature, with the aim of analyzing the multiband GC color distributions. A recent study from the SLUGGS survey has shown that the GCs in this galaxy follow a bimodal distribution of Ca II triplet indices. Thus, NGC 3115 presents a critical example of a GC system with multiple, distinct, metallicity subpopulations, and this may argue against the "projection" scenario, which posits that the ubiquitous color bimodality mainly results from nonlinearities in the color-metallicity relations. Using optical, NIR, and spectroscopic data, we found strong and consistent evidence of index bimodality, which independently confirms the metallicity bimodality in NGC 3115 GCs. At the same time, we also found evidence for some color-color nonlinearity. Taken in the broader context of previous studies, the multicolor consistency of the GC bimodality in NGC 3115 suggests that in cases where GC systems exhibit clear differences between their optical and optical-NIR color distributions (as in some giant ellipticals), the apparent inconsistencies most likely result from nonlinearities in the color-metallicity relations.
description: 5 pages (4 of supplementary online material), 2 figures, 5 tables. To be published in Astronomy & Astrophysics Letter
TT Ari and its Quasi-Periodic Oscillations
Creators: name: Smak, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Quasi-periodic oscillation (QPO) of TT Ari are transient, short-living phenomena. They appear and disappear and their periods and amplitudes vary on a time scale as short as 1 hour. Consequently the periodograms covering longer intervals of time are generally meaningless.
description: 9 pages, 7 figures, submitted to "Acta Astronomica"
Efficient Model Learning for Human-Robot Collaborative Tasks
Creators: name: Nikolaidis, Stefanos
name: Gu, Keren
name: Ramakrishnan, Ramya
name: Shah, Julie
Publisher: name: arXiv
Year: 2014
Subjects: subject: Robotics (cs.RO)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: I.2.6; I.2.8; I.2.9

description: We present a framework for learning human user models from joint-action demonstrations that enables the robot to compute a robust policy for a collaborative task with a human. The learning takes place completely automatically, without any human intervention. First, we describe the clustering of demonstrated action sequences into different human types using an unsupervised learning algorithm. These demonstrated sequences are also used by the robot to learn a reward function that is representative for each type, through the employment of an inverse reinforcement learning algorithm. The learned model is then used as part of a Mixed Observability Markov Decision Process formulation, wherein the human type is a partially observable variable. With this framework, we can infer, either offline or online, the human type of a new user that was not included in the training set, and can compute a policy for the robot that will be aligned to the preference of this new user and will be robust to deviations of the human actions from prior demonstrations. Finally we validate the approach using data collected in human subject experiments, and conduct proof-of-concept demonstrations in which a person performs a collaborative task with a small industrial robot.
Multiscale adaptive smoothing models for the hemodynamic response function in fMRI
Creators: name: Wang, Jiaping
name: Zhu, Hongtu
name: Fan, Jianqing
name: Giovanello, Kelly
name: Lin, Weili
Publisher: name: arXiv
Year: 2013
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: In the event-related functional magnetic resonance imaging (fMRI) data analysis, there is an extensive interest in accurately and robustly estimating the hemodynamic response function (HRF) and its associated statistics (e.g., the magnitude and duration of the activation). Most methods to date are developed in the time domain and they have utilized almost exclusively the temporal information of fMRI data without accounting for the spatial information. The aim of this paper is to develop a multiscale adaptive smoothing model (MASM) in the frequency domain by integrating the spatial and frequency information to adaptively and accurately estimate HRFs pertaining to each stimulus sequence across all voxels in a three-dimensional (3D) volume. We use two sets of simulation studies and a real data set to examine the finite sample performance of MASM in estimating HRFs. Our real and simulated data analyses confirm that MASM outperforms several other state-of-the-art methods, such as the smooth finite impulse response (sFIR) model.
description: Published in at http://dx.doi.org/10.1214/12-AOAS609 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Scanning plasmonic microscopy by image reconstruction from the Fourier space
Creators: name: Mollet, O.
name: Huant, S.
name: Drezet, A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We demonstrate a simple scheme for high-resolution imaging of nanoplasmonic structures that basically removes most of the resolution limiting allowed light usually transmitted to the far field. This is achieved by implementing a Fourier lens in a near-field scanning optical microscope (NSOM) operating in the leakage-radiation microscopy (LRM) mode. The method consists of reconstructing optical images solely from the plasmonic `forbidden' light collected in the Fourier space. It is demonstrated by using a point-like nanodiamond-based tip that illuminates a thin gold film patterned with a sub-wavelength annular slit. The reconstructed image of the slit shows a spatial resolution enhanced by a factor $\simeq 4$ compared to NSOM images acquired directly in the real space.
A Filterless Optical Generation Scheme of Frequency 32-Tupling Millimeter-Wave Signal Based on Cascaded Polarization Modulators
Creators: name: Yan, Xueyao
name: Wang, Dongfei
name: Wang, Xiangqing
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: In the work, a new method for generating a frequency 32-tupling millimeter-wave (mm-wave) signal with higher quality only using four polarization modulators (PolM) is proposed. To generate a pure 32-tupling mm-wave signal, it is necessary to beat ± 16th-order optical sidebands beat frequency. Mathematical calculations and simulation results both show that the scheme can obtain ± 16th-order harmonics, thereby generating frequency 32-tupling mm-wave signals. The optical sideband suppression ratio (OSSR) and radio frequency spurious suppression ratio (RFSSR) can reach 53.74 dB and 47.59 dB, respectively. Besides, the parameters that will affect OSSR and RFSSR are also analyzed and acceptable error ranges are provided.
Anisotropy of excitation and relaxation of photogenerated Dirac electrons in graphene
Creators: name: Mittendorff, Martin
name: Winzer, Torben
name: Malic, Ermin
name: Knorr, Andreas
name: Berger, Claire
name: de Heer, Walter A.
name: Schneider, Harald
name: Helm, Manfred
name: Winnerl, Stephan
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the polarization dependence of the carrier excitation and relaxation in epitaxial multilayer graphene. Degenerate pump-probe experiments with a temporal resolution of 30 fs are performed for different rotation angles of the pump-pulse polarization with respect to the polarization of the probe pulse. A pronounced dependence of the pump-induced transmission on this angle is found. It reflects a strong anisotropy of the pump-induced occupation of photogenerated carriers in momentum space even though the band structure is isotropic. Within 150 fs after excitation an isotropic carrier distribution is established. Our observations imply the predominant role of collinear scattering preserving the initially optically generated anisotropy in the carrier distribution. The experiments are well described by microscopic time-, momentum, and angle-resolved modelling, which allows us to unambiguously identify non-collinear carrier-phonon scattering to be the main relaxation mechanism giving rise to an isotropic distribution in the first hundred fs after optical excitation.
description: Submitted to Nano Letters
Large-Scale Distribution of Arrival Directions of Cosmic Rays Detected at the Pierre Auger Observatory Above $10~$PeV
Creators: name: Deligny, Olivier
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Searches for large-scale anisotropies in the distribution of arrival directions of cosmic rays detected above $\simeq 10 $PeV at the Pierre Auger Observatory are presented. Although no significant deviation from isotropy is revealed at present, some of the measurements suggest that future data will provide hints for large-scale anisotropies over a wide energy range. Those anisotropies would have amplitudes which are too small to be significantly observed within the current statistics. Assuming that the cosmic ray anisotropy is dominated by dipole and quadrupole moments in the EeV-energy range, some consequences of the present upper limits on their amplitudes are presented.
description: Proceedings of the 2nd Cosmic Ray Anisotropy Workshop, 26-28 September 2013, Madison, Wisconsin. To appear in IOP Conference Series
Systematic study of the elliptic flow parameter using a heavy-ion collision model
Creators: name: Nasim, Md.
name: Mohanty, Bedangadas
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Elliptic flow parameter, $v_{2}$ is consider as a sensitive probe for early dynamics of the heavy-ion collision. In this work we have discussed the effect of detector efficiency, procedure of centrality determination, effect of resonance decay, procedure to obtain event plane resolution on the measured $v_{2}$ by standard event plane method within the framework of a transport model. The measured value of $v_{2}$ depends on the detector efficiency in particle number counting. The effect of centrality determination is found to be negligible. The method of event-by-event correction of event plane resolution for wide centrality bin yields in results closer to the true value of $v_{2}$. The effect of resonance decay is seen to decrease the $v_{2}$ of $π$, $K$ and $p$. We also propose a procedure to correct for an event bias effect on $v_{2}$ while comparing the minimum bias centrality $v_{2}$ values for different multi-strange hadrons. Finally we have presented a model based confirmation of the recently proposed relation between $v_{2}$ obtained using event plane method and scalar product method to the true value of $v_{2}$.
description: 7 pages, 11 figures
Radiative observables for linearized gravity on asymptotically flat spacetimes and their boundary induced states
Creators: name: Benini, Marco
name: Dappiaggi, Claudio
name: Murro, Simone
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 81T30

description: We discuss the quantization of linearized gravity on globally hyperbolic, asymptotically flat, vacuum spacetimes and the construction of distinguished states which are both of Hadamard form and invariant under the action of all bulk isometries. The procedure, we follow, consists of looking for a realization of the observables of the theory as a sub-algebra of an auxiliary, non-dynamical algebra constructed on future null infinity $\Im^+$. The applicability of this scheme is tantamount to proving that a solution of the equations of motion for linearized gravity can be extended smoothly to $\Im^+$. This has been claimed to be possible provided that a suitable gauge fixing condition, first written by Geroch and Xanthopoulos, is imposed. We review its definition critically showing that there exists a previously unnoticed obstruction in its implementation leading us to introducing the concept of radiative observables. These constitute an algebra for which a Hadamard state induced from null infinity and invariant under the action of all spacetime isometries exists and it is explicitly constructed.
description: 31 pages, added references
Effect of 1000 days message disseminated through TV and radio on Maternal and Child Feeding practice, Mekelle City, Tigray region, Ethiopia
Creators: name: Yordanos Tadesse
Publisher: name: Zenodo
Year: 2018

description: Background: Undernutrition is one of the major public health challenges in Ethiopia. Poor nutritional and hygiene practice major contributors to the problem. Focusing on the crucial period from conception to the child 2nd birthday which is the 1000 days is the best time to tackle the burden of undernutrition.It ensures a good nutrition, healthy growth that has lasting benefit throughout life. One of the strategies is awareness creation using mass media which is tailored to the context of the target audiences. Addressing nutritional through behavioral communication have been done so far hence most of the messages aren’t consistent and doesn't bring satisfactory change.

Objective: To assess the effect of 1000days message disseminated through TV /Radio on maternal and child feeding practice among mothers of childfren under two years