cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Bayesian Model Selection and Parameter Estimation for Gravitational Wave Signals from Binary Black Hole Coalescences
Creators: name: Lombardi, Alexander L
Publisher: name: University of Massachusetts Amherst
Year: 2015

description: In his theory of General Relativity, Einstein describes gravity as a geometric property of spacetime, which deforms in the presence of mass and energy. The accelerated motion of masses produces deformations, which propagate outward from their source at the speed of light. We refer to these radiated deformations as gravitational waves. Over the past several decades, the goal of the Laser Interferometer Gravitational-wave Observatory (LIGO) has been the search for direct evidence of gravitational waves from astrophysical sources, using ground based laser interferometers. As LIGO moves into its Advanced era (aLIGO), the direct detection of gravitational waves is inevitable. With the technology at hand, it is imperative that we have the tools to analyze the detector signal and examine the interesting astrophysical properties of the source. Some of the main targets of this search are coalescing compact binaries. In this thesis, I describe and evaluate bhextractor, a data analysis algorithm that uses Principal Component Analysis (PCA) to identify the main features of a set of gravitational waveforms produced by the coalescence of two black holes. Binary Black Hole (BBH) systems are expected to be among the most common sources of gravitational waves in the sensitivity band of aLIGO. However, the gravitational waveforms emitted by BBH systems are not well modeled and require computationally expensive Numerical Relativity (NR) simulations. bhextractor uses PCA to decompose a catalog of available NR waveforms into a set of orthogonal Principal Components (PCs), which efficiently select the major common features of the waveforms in the catalog and represent a portion of the BBH parameter space. From these PCs, we can reconstruct any waveform in the catalog, and construct new waveforms with similar properties. Using Bayesian analysis and Nested Sampling, one can use bhextractor to classify an arbitrary BBH waveform into one of the available catalogs and estimate the parameters of the gravitational wave source.
Towards sub-kpc scale kinematics of molecular and ionized gas of star-forming galaxies at $z\sim1$
Creators: name: Girard, M.
name: Dessauges-Zavadsky, M.
name: Combes, F.
name: Chisholm, J.
name: Patricio, V.
name: Richard, J.
name: Schaerer, D.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We compare the molecular and ionized gas kinematics of two strongly lensed galaxies at $z\sim1$ based on observations from ALMA and MUSE. We derive the CO and [OII] rotation curves and dispersion profiles of these two galaxies. We find a difference between the observed molecular and ionized gas rotation curves for one of the galaxies, the Cosmic Snake, for which we obtain a spatial resolution of few hundred parsecs along the major axis. The rotation curve of the molecular gas is steeper than the rotation curve of the ionized gas. In the second galaxy, A521, the molecular and ionized gas rotation curves are consistent, but the spatial resolution is only of few kpc on the major axis. Using simulations, we investigate the effect of the thickness of the gas disk and effective radius on the observed rotation curves and find that a more extended and thicker disk smooths the curve. We also find that the presence of a strongly inclined thick disk (>1 kpc) can smooth the rotation curve because it degrades the spatial resolution along the line of sight. By building a model using a stellar disk and two gas disks, we reproduce the rotation curves of the Cosmic Snake with a molecular gas disk that is more massive and more radially and vertically concentrated than the ionized gas disk. Finally, we also obtain an intrinsic velocity dispersion in the Cosmic Snake of 18.5+-7 km/s and 19.5+-6 km/s for the molecular and ionized gas, respectively, which is consistent with a molecular disk with a smaller and thinner disk. For A521, the intrinsic velocity dispersion values are 11+-8 km/s and 54+-11 km/s, with a higher value for the ionized gas. This could indicate that the ionized gas disk is thicker and more turbulent in this galaxy. These results highlight the different spatial distribution of the molecular and ionized gas disks at $z\sim1$ and suggest the presence of thick ionized gas disks at this epoch.
description: 11 pages, 8 figures, accepted for publication in A&A
In Vitro Screening for Small-Molecule Kinase Inhibitors of Testis-Specific Serine Kinase 1 (TSSK1), a Potential Target for Male Contraception
Creators: name: Majka, Julie
Publisher: name: University of Massachusetts Amherst
Year: 2015

description: Despite the availability of a range of contraceptive methods, over 50% of pregnancies are unintended worldwide (~1,000,000/day). Male contraception remains an important area of research. Recent acceptability studies indicate that a high percentage of men would be willing to use a male contraceptive pill. Several non-hormonal targets for a male-based contraceptive pill have been brought to light recently including the testis-specific serine kinase (TSSK) family, which belongs to the AMPK kinase branch in the CAMK group. The finding that TSSK family members are postmeiotically expressed in male germ cells, together with the infertile phenotype found in both Tssk1/2 and Tssk6 mouse knock-out models, has led to the proposal that TSSKs play an important role in sperm function, making them excellent targets for drug design of novel male contraceptives. This research is aimed to the identification of potent, specific inhibitors for TSSK1 activity for the development of novel male contraceptive pills through the use of mice as an experimental model. Our hypothesis is that a single kinase inhibitor can specifically inhibit TSSK’s kinase activity without interfering with other sperm functions, or other tissue types. In this study, we have assessed the enzyme properties of vii recombinant human TSSK1 by application of a homogeneous, non-radioactive enzyme activity assay and mid-throughput screening of kinase inhibitors that block TSSK1 activity. Some of these inhibitors have proven to greatly reduce the activity of TSSK1 overall, but lack the specificity desired to be plausible for drug design. In parallel, our efforts are directed towards developing a functional in vivo assay using both CD1 and acrosin-GFP-transgenic mice (expressing Acr-GFP in the acrosome) based on our finding that TSSK1 is localized in the sperm acrosome, which points to a potential role of TSSKs in sperm acrosome reaction. The anticipated outcome of this research is to ultimately develop a reversible, non-hormonal male contraceptive. Our findings may also set the basis for studies on human sperm function towards a better understanding of male reproductive physiology and mechanisms of male infertility.
Nonequilibrium Phase Transitions in Directed Small-World Networks
Creators: name: Sanchez, Alejandro D.
name: Lopez, Juan M.
name: Rodriguez, Miguel A.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Many social, biological, and economic systems can be approached by complex networks of interacting units. The behaviour of several models on small-world networks has recently been studied. These models are expected to capture the essential features of the complex processes taking place on real networks like disease spreading, formation of public opinion, distribution of wealth, etc. In many of these systems relations are directed, in the sense that links only act in one direction (outwards or inwards). We investigate the effect of directed links on the behaviour of a simple spin-like model evolving on a small-world network. We show that directed networks may lead to a highly nontrivial phase diagram including first and second-order phase transitions out of equilibrium.
description: 4 pages, RevTeX format, 4 postscript figs, uses epsf
A Nonexistence Certificate for Projective Planes of Order Ten with Weight 15 Codewords
Creators: name: Bright, Curtis
name: Cheung, Kevin
name: Stevens, Brett
name: Roy, Dominique
name: Kotsireas, Ilias
name: Ganesh, Vijay
Publisher: name: arXiv
Year: 2019
Subjects: subject: Discrete Mathematics (cs.DM)
subject: Logic in Computer Science (cs.LO)
subject: Symbolic Computation (cs.SC)
subject: Combinatorics (math.CO)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Using techniques from the fields of symbolic computation and satisfiability checking we verify one of the cases used in the landmark result that projective planes of order ten do not exist. In particular, we show that there exist no projective planes of order ten that generate codewords of weight fifteen, a result first shown in 1973 via an exhaustive computer search. We provide a simple satisfiability (SAT) instance and a certificate of unsatisfiability that can be used to automatically verify this result for the first time. All previous demonstrations of this result have relied on search programs that are difficult or impossible to verify---in fact, our search found partial projective planes that were missed by previous searches due to previously undiscovered bugs. Furthermore, we show how the performance of the SAT solver can be dramatically increased by employing functionality from a computer algebra system (CAS). Our SAT+CAS search runs significantly faster than all other published searches verifying this result.
description: To appear in Applicable Algebra in Engineering, Communication and Computing
Anti-entropical time travel in the past is not impossible
Creators: name: mosinyan, Isaac
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 510304
subject: Thermodynamics and statistical physics
classificationCode: 510103
subject: Cosmology and extragalactic astronomy
classificationCode: 510703
subject: Particle physics
classificationCode: 460299
subject: Artificial intelligence not elsewhere classified
classificationCode: 460201
subject: Artificial life and complex adaptive systems
classificationCode: 510501
subject: Biological physics
classificationCode: 510104
subject: Galactic astronomy

description: Warning : for those that want to review the pdf file and not download it, there were issues in the figshare review system. Thats why we redirected our pdf files in a google drive public link, the viewers now can read it there, that way is not mandatory to download it. Overlooked discovery proves a form of time travel of the past is not impossible. Yes thats right, not only time travel is possible, but also complete control of time is not impossible. Throughout history, time travel has captured the imagination of both scientists and dreamers alike. From the pages of science fiction to the depths of theoretical physics, the idea of moving across time has seemed impossible, blocked by paradoxes, and constrained by the immutable laws of physics. But what if the answer lies not in bending the physical laws of the universe but in reinterpreting the nature of time itself?.
Kurandoptera purpura Rentz, Su & Ueshima 2008
Creators: name: Rentz, Dcf
name: Su, You Ning
name: Ueshima, Norhiro
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Kurandoptera
Kurandoptera purpura

description: Kurandoptera purpura (Fig. 22)
2n=25 (24t +Xt)
 Specimens examined: 2007-5, -13
The karyotype of this species comprises one pair of large, 11 pairs of small and the largest X with all telocentrics (Fig. 22a). Thus, the spermatogonial metaphase shows 25 (24 autosomes and the X (Fig. 22b). There are 12 autosomal bivalents and the sole X) at first metaphase (Fig. 22c).
description: Published as part of Rentz, Dcf, Su, You Ning & Ueshima, Norhiro, 2008, Studies in Australian Tettigoniidae: new Phaneropterine Katydids from Queensland Rainforests (Orthoptera: Tettigoniidae; Phaneropterinae), pp. 1-39 in Zootaxa 1964 (1) on page 36, DOI: 10.11646/zootaxa.1964.1.1, http://zenodo.org/record/5241847
Fermented Ophiocordyceps sinensis mycelium products for preventing contrast-associated acute kidney injury: a systematic review of randomized controlled trials
Creators: name: Pu, Fenglan
name: Li, Tianli
name: Shen, Chen
name: Wang, Yingqiao
name: Tang, Chunmei
name: Zhang, Xiaowen
name: Yan, Lijiao
name: Xu, Qihe
name: Liu, Jianping
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine

description: To evaluate the efficacy, effectiveness and safety of fermented Ophiocordyceps sinensis mycelium (FOSM) products for preventing contrast-associated acute kidney injury (CA-AKI). Randomized controlled trials were searched from four Chinese and four English electronic databases and three clinical trial registries up to July 2023. Methodological quality was assessed by using the Cochrane risk-of-bias tool 2.0. Risk difference (RD) or risk ratio (RR) and mean difference (MD) were calculated along with the 95% confidence intervals (CIs). Fourteen trials testing three types of FOSM products (Bailing, Zhiling, and Jinshuibao capsules) involving 1271 participants injected contrast agents were included. For the risk of bias, all trials were rated as some concerns. Compared with routine preventive procedure (RPP) (saline hydration and alprostadil), FOSM products plus RPP showed beneficial effects in reducing the incidence of CA-AKI (14.62% and 5.35%, respectively; RD −0.06, 95% CI −0.09 to −0.03). Subgroup analysis showed that Bailing/Jinshuibao plus RPP demonstrated lower incidence of CA-AKI compared to RPP. However, there was no statistically significant difference between Zhiling with RPP and RPP in the incidence of CA-AKI. Additionally, only when FOSM products were taken before injection of the contrast, it was superior to RPP in reducing the incidence of CA-AKI. There was no statistical difference in adverse events between these two groups. Low certainty evidence suggests that preventive oral use of FOSM products as an adjuvant agent was safe and might decrease the incidence of CA-AKI. However, high-quality placebo-controlled trials are needed to confirm its benefit.
Searching for z > 6.5 Analogs Near the Peak of Cosmic Star Formation
Creators: name: Du, Xinnan
name: Shapley, Alice E.
name: Tang, Mengtao
name: Stark, Daniel P.
name: Martin, Crystal L.
name: Mobasher, Bahram
name: Topping, Michael W.
name: Chevallard, Jacopo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Strong [OIII]$λλ$4959,5007+H$β$ emission appears to be typical in star-forming galaxies at z > 6.5. As likely contributors to cosmic reionization, these galaxies and the physical conditions within them are of great interest. At z > 6.5, where Ly$α$ is greatly attenuated by the intergalactic medium, rest-UV metal emission lines provide an alternative measure of redshift and also constraints on the physical properties of star-forming regions and massive stars. We present the first statistical sample of rest-UV line measurements in z $\sim$ 2 galaxies selected as analogs of those in the reionization era based on [OIII]$λλ$4959,5007 EW or rest-frame U-B color. Our sample is drawn from the 3D-HST Survey and spans the redshift range 1.36 $\leqslant$ z $\leqslant$ 2.49. We find that the median Ly$α$ and CIII]$λλ$1907,1909 EWs of our sample are significantly greater than those of z $\sim$ 2 UV-continuum-selected star-forming galaxies. Measurements from both individual and composite spectra indicate a monotonic, positive correlation between CIII] and [OIII], while a lack of trend is observed between Ly$α$ and [OIII] at [OIII] EW < 1000$\unicode{x212B}$. At higher [OIII] EW, extreme Ly$α$ emission starts to emerge. Using stacked spectra, we find that Ly$α$ and CIII] are significantly enhanced in galaxies with lower metallicity. Two objects in our sample appear comparable to z > 6.5 galaxies with exceptionally strong rest-UV metal line emission. These objects have significant CIV$λλ$1548,1550, HeII$λ$1640, and OIII]$λλ$1661,1665 emission in addition to intense Ly$α$ or CIII]. Detailed characterization of these lower-redshift analogs provides unique insights into the physical conditions in z > 6.5 star-forming regions, motivating future observations of reionization-era analogs at lower redshifts.
description: 22 pages, 9 figures, accepted for publication in ApJ
Promoting Extracellular Matrix Crosslinking in Synthetic Hydrogels
Creators: name: Manganare, Marcos M
Publisher: name: University of Massachusetts Amherst
Year: 2015

description: The extracellular matrix (ECM) provides mechanical and biochemical support to tissues and cells. It is crucial for cell attachment, differentiation, and migration, as well as for ailment-associated processes such as angiogenesis, metastases and cancer development. An approach to study these phenomena is through emulation of the ECM by synthetic gels constructed of natural polymers, such as collagen and fibronectin, or simple but tunable materials such as poly(ethylene glycol) (PEG) crosslinked with short peptide sequences susceptible to digestion by metalloproteases and cell-binding domains. Our lab uses PEG gels to study cell behavior in three dimensions (3D). Although this system fosters cell attachment and crosslinking peptides mentioned, the regenerative process of the ECM has not been mimicked yet in 3D synthetic gels. In an attempt to build in this functionality to PEG-based gels, I performed phage display to identify short oligopeptides that bind either collagen or fibronectin to assess them as potential nucleation points for crosslinking elements in order to emulate the in vivo reconstitution process. A phage display is a library of random oligopeptides expressed on a M13 bacteriophage that allows identification of a phenotype and a genotype with a single screening step. This inexpensive strategy could yield a short oligopeptide with high specificity. I identified the conditions under which phage display is compatible with our targets, and I isolated and identified five peptide candidates for fibronectin binding and two for collagen. Future work includes assessing whether these candidates could facilitate the formation of cell-created crosslinking in 3D synthetic hydrogels.
Isotropic cosmological singularities: other matter models
Creators: name: Tod, K. P.
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Isotropic cosmological singularities are singularities which can be removed by rescaling the metric. In some cases already studied (gr-qc/9903008, gr-qc/9903009, gr-qc/9903018) existence and uniqueness of cosmological models with data at the singularity has been established. These were cosmologies with, as source, either perfect fluids with linear equations of state or massless, collisionless particles. In this article we consider how to extend these results to a variety of other matter models. These are scalar fields, massive collisionless matter, the Yang-Mills plasma of Choquet-Bruhat, or matter satisfying the Einstein-Boltzmann equation.
description: LaTeX, 19 pages, no figures
A High-Resolution Paleoenvironmental and Paleoclimatic History of Extreme Events on the Laminated Sediment Record from Basin Pond, Fayette, Maine, U.S.A.
Creators: name: Miller, Daniel R
Publisher: name: University of Massachusetts Amherst
Year: 2015

description: Future impacts from climate change can be better understood by placing modern climate trends into perspective through extension of the short instrumental records of climate variability. This is especially true for extreme climatic events, such as extreme precipitation and wildfires, as the period of instrumental records provides only a few examples and these have likely have been influenced by anthropogenic warming. Multi-parameter records showing the past range of climate variability can be obtained from lakes. Lakes are particularly good recorders of climate variability because sediment from the surrounding environment accumulates in lakes, making them sensitive recorders of climate variability and providing high-resolution histories of local environmental conditions in the past. In some cases, such as at Basin Pond, sediment is persevered efficiently enough to produce distinguishable annual laminations (varves) in the sedimentary record. The varved record at Basin Pond was used to construct an accurate, highly-resolved age-to-depth model over the past 300 years.
Using a multi-proxy analysis, including organic biomarker analysis of molecular compounds and sedimentological features preserved in the sediment record, a history of environmental and climatic change at Basin Pond was constructed. These analyses were compared with the record of known extreme events (from instrumental measurements and historical documents), including 129 years of high-resolution precipitation and temperature meteorological data, 19 tropical systems over the past 145 years, and two known wildfire events over the past 200 years. Long-term trends in precipitation, including the increase in precipitation seen throughout the last half of the 20th century and the drought of the 1940’s, were captured in the analysis of long-chain n-alkane distributions and through varve thickness measurements obtained through X-Ray Fluorescence analysis. Furthermore, Polycyclic Aromatic Hydrocarbons (PAHs), a class of organic compounds that can be used to trace combustion activity, were found in abundance in the Basin Pond sedimentary record. Peaks in the abundances of two PAHs (retene and chrysene) and the ratio retene/(retene + chrysene) were found to be highly correlated with the known wildfire events occurring in the historical period, giving promise as using these compounds and ratio as a robust proxy for regional wildfire events in the northeastern U.S.
Tools for Data Management and Curation - HDF5 and NeXus format : Quick start cookbook
Creators: name: Bazzocchi, Federica
Publisher: name: Zenodo
Year: 2024
Subjects: HDF5
NeXus file format

description: In this lecture we  start by explaining the basic features of the HDF5 format in order to set the basis to introduce the NeXus format and its use in the material science domain. NeXus's key elements and rules are discussed by taking examples from the NXem application definition.
Differential Pulse Voltammetric Determination of Serotonin Using an Acid-Activated Multiwalled Carbon Nanotube – Over-Oxidized Poly(3,4-ethylenedioxythiophene) Modified Pencil Graphite Electrode
Creators: name: Ozge Gorduk
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Inorganic Chemistry

description: In this study, acid-activated multi-walled carbon nanotubes (AA-MWCNT) and poly(3,4-ethylenedioxythiophene) (PEDOT) were deposited on a pencil graphite electrode (PGE) surface for electrochemical sensing applications. The acid-activated multi-walled carbon nanotube/over-oxidized poly(3,4-ethylenedioxythiophene) modified pencil graphite electrode (AA-MWCNT/OO-PEDOT/PGE) was characterized using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and X-ray photoelectron spectroscopy (XPS). The sensing properties of the obtained surface were examined for the voltammetric determination of serotonin in a phosphate buffer solution. The effects of the pH, adsorption time, over-oxidation and polymerization parameters on the electrochemical properties of serotonin were investigated. The effects of possible interfering substances were evaluated. The detection limit was determined to be 0.092 µM based on a signal-to-noise ratio of 3. Analytical applications of AA-MWCNT/OO-PEDOT/PGE were successfully tested for the determination of serotonin in human blood serum samples.
Researches on Relationship between Circular Agriculture and Industrial Diversity
Creators: name: Zuo, Mi
name: Feng, Gong
name: Zuo, Mi
name: Feng, Gong
Publisher: name: Unknown
Year: 2011
Subjects: subject: Agribusiness
subject: Circular agriculture
subject: Circular material
subject: Industrial diversity
subject: Closeness
subject: Openness
subject: China

description: First, this paper establishes the conceptual model of circular agriculture, conducts systematic analysis on the circular agriculture on the basis of conceptual model, and discusses the characteristics of closeness and openness of circular agriculture and relationship between closeness and openness of circular agriculture. Second, this paper introduces the industrial diversity related to circular agriculture, defines the concept of industry and the concept of industries related to agriculture, and illustrates the related industries that are conducive to circular agriculture and the related industries that are not conducive to circular agriculture. Finally, this paper analyzes the mutual relationship between circular agriculture and industrial diversity as follows, in the system of circular agriculture, the industrial diversity can transform the wastes in upstream industries into resources in downstream industries; the industrial diversity creates possibility for recycling of agricultural byproducts; the industrial diversity is conducive to the diversification of industries related to circular agriculture.
Four Puzzles of Neutrino Mixing
Creators: name: Barr, S. M.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: There are four puzzling questions about by the magnitudes of neutrino mixings and mass splittings. A brief sketch is given of the various kinds of models of neutrino masses and how they answer these questions. Special attention is given to so-called "lopsided" models.
description: 12 pages, LaTeX. Talk at NOON2001 conference, Univ. of Tokyo, Dec. 5-8, 2001
Identification of common and specific fibrosis-related genes in three common chronic kidney diseases
Creators: name: Fu, Zhangning
name: Geng, Xiaodong
name: Liu, Chao
name: Shen, Wanjun
name: Dong, Zheyi
name: Sun, Guannan
name: Cai, Guangyan
name: Chen, Xiangmei
name: Hong, Quan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Kidney fibrosis is the common final pathway of virtually all advanced forms of chronic kidney disease (CKD) including diabetic nephropathy (DN), IgA nephropathy (IgAN) and membranous nephropathy (MN), with complex mechanism. Comparative gene expression analysis among these types of CKD may shed light on its pathogenesis. Therefore, we conducted this study aiming at exploring the common and specific fibrosis-related genes involved in different types of CKD. Kidney biopsy specimens from patients with different types of CKD and normal control subjects were analyzed using the NanoString nCounter® Human Fibrosis V2 Panel. Genes differentially expressed in all fibrotic DN, IgAN and MN tissues compared to the normal controls were regarded as the common fibrosis-related genes in CKD, whereas genes exclusively differentially expressed in fibrotic DN, IgAN or MN samples were considered to be the specific genes related to fibrosis in DN, IgAN and MN respectively. Quantitative real-time PCR (qRT-PCR) was performed to validate the expression of the selected genes. Protein tyrosine phosphatase receptor type C (PTPRC), intercellular cell adhesion molecule-1 (ICAM1), vascular cell adhesion molecule-1 (VCAM1), interleukin 10 receptor alpha (IL10RA) and CC chemokine receptor 2 (CCR2) were identified as the potential common genes for kidney fibrosis in different types of CKD, while peroxisome proliferator-activated receptor alpha (PPARA), lactate oxidase (LOX), secreted phosphoprotein 1 (SPP1) were identified as the specific fibrosis-associated genes for DN, IgAN and MN respectively. qRT-PCR demonstrated that the expression levels of these selected genes were consistent with the NanoString analysis. There were both commonalities and differences in the mechanisms of fibrosis in different types of CKD, the commonalities might be used as the common therapeutic targets for kidney fibrosis in CKD, while the differences might be used as the diagnostic markers for DN, IgAN and MN respectively. Inflammation was highly relevant to the pathogenesis of fibrosis. This study provides further insight into the pathophysiology and treatment of fibrotic kidney disease.
BC-SIM-TR-013 - STC ICO1 REPORT Issue 1.0
Creators: name: SIMIONI, EMANUELE
name: SLEMER, ALESSANDRA
name: Da Deppo, Vania
name: ZUSI, MICHELE
name: POLITI, ROMOLO
name: RE, Cristina
name: Carlier, Vincent
name: CAMBIANICA, PAMELA
name: CAPACCIONI, FABRIZIO
name: CAPRIA, MARIA TERESA
name: Doressundiram, Alain
name: Langeven, Yves
name: PALUMBO, PASQUALE
name: Vincendon, Mathieu
name: CREMONESE, Gabriele
Publisher: name: O.A. Padova
Year: 2021

description: The present document has been issued to describe the Instrument Check Out Phase (ICO#1) Tests of STC, channel of the Spectrometers and Imagers for MPO BepiColombo Integrated Observatory SYStem (SIMBIO-SYS).
Diastella kuranda Rentz, Su & Ueshima 2008
Creators: name: Rentz, Dcf
name: Su, You Ning
name: Ueshima, Norhiro
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Proteales
Proteaceae
Diastella
Diastella kuranda

description: Diastella kuranda (Fig. 23)
2n=21 (20t +Xt)
 Specimens examined: 2006-3, -4, -8, -9, 2007-6
The karyotype of this species consists of one pair of large, 9 pairs of medium to small, and the largest X (Fig. 23a). They are all telocentrics. At first metaphase 9 autosomal bivalents and the sole X are seen (Fig. 23b). As a result of the first division, there are 10 autosomes with the X (Fig. 23c) and 10 autosomes (Fig. 23d).
description: Published as part of Rentz, Dcf, Su, You Ning & Ueshima, Norhiro, 2008, Studies in Australian Tettigoniidae: new Phaneropterine Katydids from Queensland Rainforests (Orthoptera: Tettigoniidae; Phaneropterinae), pp. 1-39 in Zootaxa 1964 (1) on page 38, DOI: 10.11646/zootaxa.1964.1.1, http://zenodo.org/record/5241847
Exposure to 1,3-Butadiene in the U.S. Population: National Health and Nutrition Examination Survey 2011–2016
Creators: name: Nieto, Alma
name: Luyu Zhang
name: Bhandari, Deepak
name: Wanzhe Zhu
name: Blount, Benjamin C.
name: De Jesús, Víctor R.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: 1,3-Butadiene is a volatile organic compound with a gasoline-like odour that is primarily used as a monomer in the production of synthetic rubber. The International Agency for Research on Cancer has classified 1,3-butadiene as a human carcinogen. We assessed 1,3-butadiene exposure in the U.S. population by measuring its urinary metabolites N-acetyl-S-(3,4-dihydroxybutyl)-L-cysteine (34HBMA), N-acetyl-S-(1-hydroxymethyl-2-propenyl)-L-cysteine (1HMPeMA), N-acetyl-S-(2-hydroxy-3-butenyl)-L-cysteine (2HBeMA), and N-acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine (4HBeMA). Urine samples from the 2011 to 2016 National Health and Nutrition Examination Survey were analysed for 1,3-butadiene metabolites using ultrahigh-performance liquid chromatography/tandem mass spectrometry. 34HBMA and 4HBeMA were detected in >96% of the samples; 1HMPeMA and 2HBeMA were detected in 0.66% and 9.84% of the samples, respectively. We used sample-weighted linear regression models to examine the influence of smoking status (using a combination of self-reporting and serum-cotinine data), demographic variables, and diet on biomarker levels. The median 4HBeMA among exclusive smokers (31.5 µg/g creatinine) was higher than in non-users (4.11 µg/g creatinine). Similarly, the median 34HBMA among exclusive smokers (391 µg/g creatinine) was higher than in non-users (296 µg/g creatinine). Furthermore, smoking 1–10, 11–20, and >20 cigarettes per day (CPD) was associated with 475%, 849%, and 1143% higher 4HBeMA (p 20 CPD was associated with 33%, 44%, and 102% higher 34HBMA (p
Asymmetric Chern-Simons number diffusion from CP-violation
Creators: name: Nauta, Bert-Jan
name: Arrizabalaga, Alejandro
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study Chern-Simons number diffusion in a SU(2)-Higgs model with CP-odd dimension-eight operators. We find that the thermal average of the magnitude of the velocity of the Chern-Simons number depends on the direction of the velocity. This implies that the distribution function of the Chern-Simons number will develop an asymmetry. It is argued that this asymmetry manifests itself through a linear growth of the expectation value of the third power of the Chern-Simons number. This linear behavior of the third power of a coordinate of a periodic direction is verified by a numerical solution of a one-dimensional Langevin equation. Further, we make some general remarks on thermal averages and on the possibility of the generation of the baryon asymmetry in a non-equilibrium situation due to asymmetric diffusion of the Chern-Simons number.
description: 26 pages, 4 figures
IIB flux non-commutativity and the global structure of field theories
Creators: name: García-Etxebarria, Iñaki
name: Heidenreich, Ben
name: Regalado, Diego
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss the origin of the choice of global structure for six dimensional $(2,0)$ theories and their compactifications in terms of their realization from IIB string theory on ALE spaces. We find that the ambiguity in the choice of global structure on the field theory side can be traced back to a subtle effect that needs to be taken into account when specifying boundary conditions at infinity in the IIB orbifold, namely the known non-commutativity of RR fluxes in spaces with torsion. As an example, we show how the classification of $\mathcal{N}=4$ theories by Aharony, Seiberg and Tachikawa can be understood in terms of choices of boundary conditions for RR fields in IIB. Along the way we encounter a formula for the fractional instanton number of $\mathcal{N}=4$ ADE theories in terms of the torsional linking pairing for rational homology spheres. We also consider six-dimensional $(1,0)$ theories, clarifying the rules for determining commutators of flux operators for discrete 2-form symmetries. Finally, we analyze the issue of global structure for four dimensional theories in the presence of duality defects.
description: 72 pages
A Lattice-Boltzmann method for the simulation of transport phenomena in charged colloids
Creators: name: Horbach, Juergen
name: Frenkel, Daan
Publisher: name: arXiv
Year: 2001
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We present a new simulation scheme based on the Lattice-Boltzmann method to simulate the dynamics of charged colloids in an electrolyte. In our model we describe the electrostatics on the level of a Poisson-Boltzmann equation and the hydrodynamics of the fluid by the linearized Navier-Stokes equations. We verify our simulation scheme by means of a Chapman-Enskog expansion. Our method is applied to the calculation of the reduced sedimentation velocity U/U_0 for a cubic array of charged spheres in an electrolyte. We show that we recover the analytical solution first derived by Booth (F. Booth, J. Chem. Phys. 22, 1956 (1954)) for a weakly charged, isolated sphere in an unbounded electrolyte. The present method makes it possible to go beyond the Booth theory, and we discuss the dependence of the sedimentation velocity on the charge of the spheres. Finally we compare our results to experimental data.
description: 18 pages, 5 figures, to appear in Phys. Rev. E
Theory of Dipole Insulators
Creators: name: Dubinkin, Oleg
name: May-Mann, Julian
name: Hughes, Taylor L.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Insulating systems are characterized by their insensitivity to twisted boundary conditions as quantified by the charge stiffness and charge localization length. The latter quantity was shown to be related to the expectation value of the many-body position operator and serves as a universal criterion to distinguish between metals and insulators. In this work we extend these concepts to a new class of quantum systems having conserved charge and dipole moments. We refine the concept of a charge insulator by introducing notions of multipolar insulators, e.g., a charge insulator could be a dipole insulator or dipole metal. We develop a universal criterion to distinguish between these phases by extending the concept of charge stiffness and localization to analogous versions for multipole moments, but with our focus on dipoles. We are able relate the dipole localization scale to the expectation value of a recently introduced many-body quadrupole operator. This refined structure allows for the identification of phase transitions where charge remains localized but, e.g., dipoles delocalize. We illustrate the proposed criterion using several exactly solvable models that exemplify these concepts, and discuss a possible realization in cold-atom systems.
description: 11+4 pages, 2 figures
Innovation of China's Circular Agricultural Development in the Perspective of Low Carbon Economy
Creators: name: Li, Yan-Yan
name: Li, Yan-Yan
Publisher: name: Unknown
Year: 2011
Subjects: subject: Agribusiness
subject: New village
subject: Development
subject: Circular agriculture
subject: Low carbon economy
subject: China

description: On the basis of the concept and characteristics of circular economy, this paper analyzes the restraining factors of China's circular agricultural development as follows: issues concerning agriculture, countryside and farmers are outstanding; the problems of agricultural resources and agricultural ecological environment are serious; the quality of agricultural products cannot meet the demand of domestic and international market for food. Based on the internal requirements of low carbon economic development, this paper advances four innovative models concerning China's circular agricultural development as follows: the model of combining planting and breeding of agriculture, the developmental model of leisure and sightseeing, ecological integration model, and the developmental model of reusing. agricultural byproducts Every region should choose or create different circular agricultural model in different domains, in order to better use agricultural resources, reduce the consumption of agricultural energy inputs, reduce the emission of agricultural greenhouse gas, develop low carbon agriculture, and make great contribution for meeting the international challenges and promoting China's agricultural development .
A Converse Hawking-Unruh Effect and dS^2/CFT Correspondance
Creators: name: Guido, Daniele
name: Longo, Roberto
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Operator Algebras (math.OA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Given a local quantum field theory net A on the de Sitter spacetime dS^d, where geodesic observers are thermalized at Gibbons-Hawking temperature, we look for observers that feel to be in a ground state, i.e. particle evolutions with positive generator, providing a sort of converse to the Hawking-Unruh effect. Such positive energy evolutions always exist as noncommutative flows, but have only a partial geometric meaning, yet they map localized observables into localized observables. We characterize the local conformal nets on dS^d. Only in this case our positive energy evolutions have a complete geometrical meaning. We show that each net has a unique maximal expected conformal subnet, where our evolutions are thus geometrical. In the two-dimensional case, we construct a holographic one-to-one correspondence between local nets A on dS^2 and local conformal non-isotonic families (pseudonets) B on S^1. The pseudonet B gives rise to two local conformal nets B(+/-) on S^1, that correspond to the H(+/-)-horizon components of A, and to the chiral components of the maximal conformal subnet of A. In particular, A is holographically reconstructed by a single horizon component, namely the pseudonet is a net, iff the translations on H(+/-) have positive energy and the translations on H(-/+) are trivial. This is the case iff the one-parameter unitary group implementing rotations on dS^2 has positive/negative generator.
description: The title has changed. 38 pages, figures. To appear on Annales H. Poincare'
Characterization of the Reconstituted and Native Pseudomonas aeruginosa Type III Secretion System Translocon
Creators: name: Monopoli, Kathryn R
Publisher: name: University of Massachusetts Amherst
Year: 2016

description: The Type III Secretion (T3S) system is a system utilized by many pathogenic bacteria to inject proteins into host cells during an infection. Effector proteins enter the host cell by passing through the proteinaceous T3S translocon, which forms a pore on the host cell membrane. Pseudomonas aeruginosa is an opportunistic pathogen that utilizes the T3S system, and very little is known about how the P. aeruginosa translocon forms.
The proteins PopB and PopD are believed to assemble into the P. aeruginosa translocon. A pore-forming heterocomplex of PopB and PopD has been reconstituted in model membranes, however this heterocomplex has not been assessed in its relation to the translocon formed on the host cell. The interaction of this heterocomplex with other T3S system components was measured to determine if this complex acts similarly to the translocon. Initial assays that can be used to compare the molecular weight of the translocon isolated from eukaryotic cells after P. aeruginosa contact to the calculated molecular weight of the heterocomplex were developed as well. This study provides insight into how the PopB:PopD heterocomplex formed in model membranes relates to the translocon formed during a P. aeruginosa infection.
Analysis of Input and Output of China's Agriculture Based on Canonical Correlation
Creators: name: Chen, Daoping
name: Chen, Daoping
Publisher: name: Unknown
Year: 2011
Subjects: subject: Agribusiness
subject: Agriculture
subject: Input
subject: Output
subject: Canonical correlation
subject: China

description: I select effective irrigated area, consumption of agricultural chemical fertilizer, electricity consumed in rural areas, and total power of agricultural machinery as input variables of China's agriculture; I select grain, bean, tobacco, oil-bearing crop and fruit as output variables of China's agriculture. By using the data of China Statistical Yearbook in 2010, based on the analysis method of canonical correlation, I conduct research on the input and output of China's agriculture. The results show that consumption of chemical fertilizer has the biggest impact on the agricultural output of China, followed by the input of total power of agricultural machinery; the canonical variable of agricultural output of China is mainly impacted by grain, oil-bearing crop and fruit; in terms of the selected variables, the output increase of grain, oil-bearing crop and fruit in China arises from the input increase of agricultural chemical fertilizer and machinery, and there the policy suggestions are put forward as follows: gradually decrease consumption of chemical fertilizer; increase the use of modem agricultural machinery; increase agricultural irrigation input.
From the bulge to the outer disc: StarHorse stellar parameters, distances, and extinctions for stars in APOGEE DR16 and other spectroscopic surveys
Creators: name: Queiroz, A. B. A.
name: Anders, F.
name: Chiappini, C.
name: Khalatyan, A.
name: Santiago, B. X.
name: Steinmetz, M.
name: Valentini, M.
name: Miglio, A.
name: Bossini, D.
name: Barbuy, B.
name: Minchev, I.
name: Minniti, D.
name: Hernández, D. A. García
name: Schultheis, M.
name: Beaton, R. L.
name: Beers, T. C.
name: Bizyaev, D.
name: Brownstein, J. R.
name: Cunha, K.
name: Fernández-Trincado, J. G.
name: Frinchaboy, P. M.
name: Lane, R. R.
name: Majewski, S. R.
name: Nataf, D.
name: Nitschelm, C.
name: Pan, K.
name: Roman-Lopes, A.
name: Sobeck, J. S.
name: Stringfellow, G.
name: Zamora, O.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We combine high-resolution spectroscopic data from APOGEE-2 Survey Data Release 16 (DR16) with broad-band photometric data from several sources, as well as parallaxes from {\it Gaia} Data Release 2 (DR2). Using the Bayesian isochrone-fitting code {\tt StarHorse}, we derive distances, extinctions and astrophysical parameters for around 388,815 APOGEE stars, achieving typical distance uncertainties of $\sim 6\%$ for APOGEE giants, $\sim 2\%$ for APOGEE dwarfs, as well as extinction uncertainties of $\sim 0.07$ mag when all photometric information is available, and $\sim 0.17$ mag if optical photometry is missing. {\tt StarHorse} uncertainties vary with the input spectroscopic catalogue, with the available photometry, and with the parallax uncertainties. To illustrate the impact of our results, we show that, thanks to {\it Gaia} DR2 and the now larger sky coverage of APOGEE-2 (including APOGEE-South), we obtain an extended map of the Galactic plane, providing unprecedented coverage of the disk close to the Galactic mid-plane ($|Z_{Gal}|<1$ kpc) from the Galactic Centre out to $R_{\rm Gal}\sim 20$ kpc. The improvements in statistics as well as distance and extinction uncertainties unveil the presence of the bar in stellar density, as well as the striking chemical duality in the innermost regions of the disk, now clearly extending to the inner bulge. We complement this paper with distances and extinctions for stars in other public released spectroscopic surveys: 324,999 in GALAH DR2, 4,928,715 in LAMOST DR5, 408,894 in RAVE DR6, and 6,095 in GES DR3
description: Accepted to A&A. 17 pages, 11 figures. Data products are available at https://data.aip.de/aqueiroz2020, (doi:10.17876/data/2020_2)