cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Regulation of global gene expression in brain by TMP21
Creators: name: Zhang, Xiaojie
name: Wu, Yili
name: Cai, Fang
name: Song, Weihong
Publisher: name: BioMed Central
Year: 2019

description: TMP21, a type I transmembrane protein of thep24 protein family, mediates protein trafficking and maturation. Dysregulation of TMP21 is implicated in the pathogenesis of Alzheimer’s disease (AD). However, underlying mechanisms remain elusive. To reveal the function of TMP21 in the brain and the pathogenic role of TMP21 in the brain of AD, the global gene expression was profiled in the brain of TMP21 knockdown mice. We found that 8196 and 8195 genes are significantly altered in the hippocampus and cortex, respectively. The genes are involved in a number of brain function-related pathways, including glutamatergic synapse pathway, serotonergic synapse pathway, synaptic vesicle pathway, and long-term depression pathway. Moreover, the network analysis suggests that the TMP21 may contribute to the pathogenesis of AD by regulatingPI3K/Akt/GSK3β signalling pathway. Our study provides an insight into the physiological function of TMP21 in the brain and pathological role of TMP21 in AD.
title: Proportions of regulatory T cells (Treg) and suppressive Treg function in patients with psoriasis arthritis (PsA) or spondyloarthritis (SpA) after switching to anti-IL-17 treatment
Creators: name: Prelog, Martina
name: Christoforou, Timotheos
name: Almanzar, Giovanni
name: Brauneiser, Franziska
name: Buschmann, Nils
name: Feuchtenberger, Martin
name: Schmalzing, Marc
name: Tony, Hans-Peter
name: Goebeler, Matthias
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Introduction: A dysbalance between IL-17-producing helper T (Th17) cells and regulatory T cells (Treg) has been proposed for T cell-mediated autoimmune arthritis. Blockers of IL-17 are successfully used for psoriatic arthritis (PsA) and spondyloarthritis (SpA). However, so far reconstitution of Treg[for full text, please go to the a.m. URL]
description: Deutscher Rheumatologiekongress 2020, 48. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 34. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh)
Holistic sport psychology: Incorporating the holistic growth of the athlete within a consultant's professional philosophy
Creators: name: Friesen, Andrew
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Health Sciences, Recreation.

description: The present qualitative study aimed to explore the integration of holistic athlete development into sport psychology service delivery. Using the framework of professional philosophy from Poczwardowski, Sherman, and Ravizza (2004), five holistic sport psychology consultants were interviewed about their service delivery. Five athletes were also interviewed about their experiences working with these consultants. Deductive and inductive content analyses (Patton, 2002) were used to examine the data collected. Results offer three perspectives as to the meaning of holistic sport psychology: (a) Managing environmental effects from non-sport domains to the athlete's performance; (b) developing the individual beyond the athlete; and (c) recognizing the dynamic relationship between an athlete's mental, emotional, physiological states, and their behaviour. Themes from the consultants' beliefs, values, theoretical paradigms to behaviour change, models of practice, roles, operating standards, intervention goals, and intervention techniques and methods are also presented and discussed within the context of various service delivery topics.
Supplementary document for High-speed CMOS-compatible III-V/Si photodetectors - 4989080.pdf
Creators: name: Baumgartner, Yannick
name: Caimi, Daniele
name: Sousa, Marilyne
name: Hopstaken, Marco
name: Salamin, Yannick
name: Bauerle, Benedikt
name: Bitachon, Bertold Ian
name: Leuthold, Juerg
name: Faist, Jérôme
name: Offrein, Bert
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplemental document
A mechanistic and synthetic study on Ziegler-Natta polymerization catalysts based on vanadium complexes.
Creators: name: Ma, Yinlin.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Chemistry, Inorganic.

description: A series of V(III) catalysts with different substituted 1,3-dionates $\rm(V(acac)\sb3$ 2.1, V(Cy-$\rm acac)\sb3$ 2.2, V(t-Bu-$\rm acac)\sb3$ 2.3 and V(F-$\rm acac)\sb3$ 2.4 were prepared and characterized and their activities towards olefin polymerization were systematically compared. V(Cy-$\rm acac)\sb3$ 2.2 shows a slightly higher activity than the traditional catalyst $\rm V(acac)\sb3$ 2.1. The catalytically active species is relatively insensitive to modification of both the electronic and steric features of the acac ligand. The preparation of V(II) and V(IV) 1,3-dionate complexes was designed to study the role of the oxidation state of vanadium in terms of polymerization activity. Two unprecedented V(II) complexes (R-$acac)\sb2\rm V(TMEDA)$ (R = H(2.7), t-Bu (2.7c)) have been prepared and reacted with halocarbons to model the reactivation process. The isolation of (t-Bu-$acac)\sb2\rm V(TMEDA)\rbrack\lbrack X\rbrack\ \lbrack X = ZnCl\sb4\sp-$ 2.8, $\rm CuCl\sb2\sp-$ 2.9) indicates that the primary role of reactivating substances, commonly employed in the industrial processes, is to reoxidize V(II) to the trivalent state. Reaction of $\rm VCl\sb3(THF)\sb3$ with two equivalent of $\rm R\sp1(R\sp2)NLi{\cdot}Et\sb2O\ (R\sp1 = Ph,$ Bz; $\rm R\sp2 = Bz)$ gave the paramagnetic and monomeric $\rm\lbrack R\sp1(R\sp2)N\rbrack\sb4V$ (3.1) and (3.2). Reactions of $\rm VCl\sb3(THF)\sb3$ with one equivalent of $\rm R\sp1(R\sp2)NLi\ (R\sp1 = Bz;\ R\sp2 = Ph)$ and $\rm R\sb2NLi$ (R = Bz) formed the paramagnetic, monomeric $\rm\lbrack R\sp1(R\sp2)N\rbrack\sb3VCl$ (3.3) and $\rm\lbrack R\sb2N\rbrack\sb3VCl$ (3.4). Reaction of $\rm VCl\sb3(THF)\sb3$ with an excess of $\rm NaBH\sb4$ gave the paramagnetic and monomeric $\rm V(BH\sb4)\sb2(THF)\sb3$ (4.1), $\rm V(BH\sb4)\sb2(TMEDA)\sb2$ (4.2), and $\rm V(BH\sb4)\sb2(py)\sb4$ (4.3). (Abstract shortened by UMI.)
title: Klimawandel und Gesundheit
title: Klimawandel und Gesundheit
titleType: AlternativeTitle
Creators: name: Mücke, Hans-Guido
name: Matzarakis, Andreas
Publisher: name: Umweltbundesamt
Year: 2019
Subjects: subject: Gesundheit
subject: Hitze
subject: Klima | Energie
subject: Gesundheit

description: Lang anhaltende Perioden extremer Hitze - so genannte Hitzewellen - treten seit etwa 30 Jahren in ungewöhnlicher Häufigkeit in Europa und in Deutschland auf. Die dadurch ausgelösten gesundheitlichen Belastungen können erheblich, mitunter lebensbedrohend sein. Der Sommer 2018 war der zweitheißeste seit Beginn der Wetteraufzeichnungen 1881. Er folgt dem bislang heißesten des Jahres 2003, der in mehreren Ländern Westeuropas insgesamt weit über 40 000 Menschenleben forderte (in Deutschland etwa 7 000). Die erhöhte hitzebedingte Mortalität betrifft vor allem ältere Menschen. Der Ratgeber gibt wichtige Hinweise für ein angepasstes und individuelles Gesundheitsverhalten bei sommerlicher Hitze. Quelle: https://www.umweltbundesamt.de
description: Lang anhaltende Perioden extremer Hitze – so genannte Hitzewellen – treten seit etwa 30 Jahren in ungewöhnlicher Häufigkeit in Europa und in Deutschland auf. Die dadurch ausgelösten gesundheitlichen Belastungen können erheblich, mitunter lebensbedrohend sein. Der Sommer 2018 war der zweitheißeste in Deutschland seit Beginn der Wetteraufzeichnungen 1881. Er folgt dem bislang heißesten des Jahres 2003, der in mehreren Ländern Westeuropas insgesamt weit über 40 000 Menschenleben forderte (in Deutschland etwa 7 000). Die erhöhte hitzebedingte Mortalität betrifft vor allem ältere Menschen. Der Ratgeber gibt wichtige Hinweise für ein angepasstes und individuelles Gesundheitsverhalten bei sommerlicher Hitze.
Supplementary document for Photoconductive terahertz generation in semi-insulating GaAs and InP under the extremes of bias field and pump fluence - 4990110.pdf
Creators: name: Alfihed, Salman
name: Jenne, Matthias
name: Ciocoiu, Antonia
name: Foulds, Ian
name: Holzman, Jonathan
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
Hip-Hop Culture Invasion: A Dialogue Between America and Italy
Creators: name: Fascina, Camilla
Publisher: name: Iperstoria
Year: 2020

description: “Rapping is part of the cultural heritage of Black ghetto life. According to Black semantics it not only denotes ordinary conversation, but also defines specific ways of communication. In the 1960s many linguists, sociologists and psychologists conducted thorough research on the behaviour and language-use of ‘ghetto Blacks’” (Remes). In his book Black Popular Music in America, Arnold Shaw reports that rapping has been associated with the hip-hop culture “since the mid Seventies in the United States and that it originated in the South Bronx, New York (...) where hip-hop started as a collective and positive reaction against the spiral of violence of street gangs”. In sociolinguistic studies rapping is described as “fluent, lively speech, highly determined by personal style” (Folb), and rap performances are defined as a “display of complex structures of communication” (Remes). Taking into consideration these definitions, the aim of the present study is to observe in which ways hip-hop as a “language” and, metaphorically speaking, as a “communication vector,” develops in Italy. In order to reflect on these aspects, an overview of the Italian hip-hop scene will be outlined through the analysis of specific songs by Italian MCs.
description: Iperstoria, No 6 (2015): La 'realtà' trasnazionale della razza. Dinamiche di razzializzazione in prospettiva comparata
Chemodynamical evolution of the Milky Way disk I: The solar vicinity
Creators: name: Minchev, I.
name: Chiappini, C.
name: Martig, M.
Publisher: name: Swinburne
Year: 2024

description: In the first paper of this series, we present a new approach for studying the chemo-dynamical evolution in disk galaxies, which consists of fusing disk chemical evolution models with compatible numerical simulations of galactic disks. This method avoids known star formation and chemical enrichment problems encountered in simulations. Here we focus on the Milky Way, by using a detailed thin-disk chemical evolution model (matching local observables, which are weakly affected by radial migration) and a simulation in the cosmological context, with dynamical properties close to those of our Galaxy. We examine in detail the interplay between in situ chemical enrichment and radial migration and their impact on key observables in the solar neighborhood, e. g., the age-metallicity-velocity relation, the metallicity distribution, and gradients in the radial and vertical directions. We show that, due to radial migration from mergers at high redshift and the central bar at later times, a sizable fraction of old metal-poor high-[alpha/Fe] stars can reach the solar vicinity. This naturally accounts for a number of recent observations related to both the thin and thick disks, despite the fact that we use thin-disk chemistry only. Although significant radial mixing is present, the slope in the age-metallicity relation is only weakly affected, with a scatter compatible with recent observational work. While we find a smooth density distribution in the [O/Fe]-[Fe/H] plane, we can recover the observed discontinuity by selecting particles according to kinematic criteria used in high-resolution samples to define the thin and thick disks. We outline a new method for estimating the birth place of the Sun and predict that the most likely radius lies in the range 4.4 < r < 7.7 kpc (for a current location at r = 8 kpc). A new, unifying model for the Milky Way thick disk is offered, where both mergers and radial migration play a role at different stages of the disk evolution. We show that in the absence of early-on massive mergers the vertical velocity dispersion of the oldest stars is underestimated by a factor of similar to 2 compared with observations. We can, therefore, argue that the Milky Way thick disk is unlikely to have been formed through a quiescent disk evolution. An observational test involving both chemical and kinematic information must be devised to ascertain this possibility.
title: Differential phenotypes of disease-specific auto-reactive B cell responses in patients with Systemic Sclerosis
Creators: name: Scherer, Hans Ulrich
name: Wortel, Corrie
name: Van Leeuwen, Nina
name: Boonstra, Maaike
name: Toes, René
name: Huizinga, Thomas
name: De Vries-Bouwstra, Jeska
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Introduction: Systemic Sclerosis (SSc) carries the highest mortality burden among the rheumatic diseases. >95% of SSc patients harbor autoantibodies. Anti-topoisomerase antibodies (ATA) and anti-centromere antibodies (ACA) are most prevalent, mutually exclusive in individual patients, associate[for full text, please go to the a.m. URL]
description: Deutscher Rheumatologiekongress 2020, 48. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 34. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh)
Semi-automatic generation of CHR solvers from global constraint automata
Creators: name: Raiser, Frank
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Constraints
subject: Global constraints
subject: DDC 004 / Data processing & computer science
subject: Constraint programming (Computer science)
subject: CHR
subject: Constraint-Programmierung

description: Constraint programming often involves global constraints, which have been catalogued in [1] and for which various custom filtering algorithms have been published. This work presents a semi-automatic generation of CHR solvers for the set of global constraints which can be defined by specific automata described in [2]. The solvers only need to be generated once and achieve arc-consistency for over 40 global constraints.
Characterization of apolipoprotein A-I functional domains.
Creators: name: Frank, Philippe Guy.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Biology, Molecular.

description: The plasma concentration of high-density lipoprotein (HDL) is inversely correlated to the development of coronary heart disease. This inverse relationship has been attributed to the role that HDL and its major constituent, apolipoprotein A-I (apoA-I), play in reverse cholesterol transport. This pathway allows HDL to acquire excess cellular cholesterol from peripheral cells and mediate its transport to the liver for degradation and removal from the body. ApoA-I has three major functions in this process. In order to identify the different domains of human apoA-I involved in these functions, a bacterial expression system was designed. This expression system was used to express apoA-I mutants and to identify the specific domains responsible of its functions. Three apoA-I mutants, corresponding to deletions of apoA-I residues 100--143, 122--165, 144--186, have been characterized for their ability to bind phospholipids; and to form reconstituted apoA-I-containing lipoproteins, as well as for their structural and physical properties. The results show that the amphipathic alpha-helices within residues 100--186 are directly involved in the interactions with phospholipids and determine the lipid binding capacity of the protein. We have also examined the contribution of these amphipathic alpha-helices to the ability of apoA-I to promote cholesterol efflux from human skin fibroblasts. All central deletion mutants in reconstituted HDL could acquire cellular cholesterol from normal fibroblasts with similar affinity and binding capacity for cholesterol. The contribution of amphipathic: alpha-helices (central and C-terminal helices) to the ability of lipid-free apoA-I to promote cellular cholesterol efflux was examined with cholesterol-loaded fibroblasts and macrophages. ApoA-I interaction and cholesterol efflux from cells such as fibroblasts, which accumulate moderate amounts of cholesterol, do not require any specific sequence between residues 100 and 243. We have examined the ability of the central domain deletion mutants in reconstituted lipoproteins to activate the reaction mediated by LCAT. Deletion of residues 122--165 or 144--186 results in an inability of the mutant apoproteins to promote cholesterol esterification. This study and others suggest that apoA-I contains three functionally distinct domains: the N-terminal domain plays an important role in the stabilization of the lipid-free protein; the C-terminal domain is involved in the initial binding of lipids; the central domain mediates the maturation of high density lipoproteins. (Abstract shortened by UMI.)
Autonomer Mess Roboter : Abschlussbericht zur vorzeitigen Beendigung der Mitarbeit der Firma Cubert im Projekt AuMeRo
Creators: name: Heine, René
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: 3D-Messtechnik
subject: Snapshot Spektroskopie
subject: CCMS
subject: Chromatisch-konfokaler Multispotsensor
subject: DDC 620 / Engineering & allied operations
subject: Three-dimensional imaging
subject: Optical admittance spectroscopy
subject: Robotics
subject: Autonomous robots
subject: Optische Messtechnik
subject: Optische Spektroskopie
subject: Multisensor

description: Im Rahmen der Entwicklung eines Autonomen Messroboters wurde in diesem Teilprojekt die Miniaturisierung eines 3D Sensors untersucht. Dazu wurde die Anwendbarkeit von Snapshot Spektralsensoren (IMEC) zur Integration in einen chromatisch-konfokalen Multipunktsensor (CCMS) zur 3D-Vermessung erforscht.
"Nothing Beats the Bible." Il fondamentalismo cristiano e le primarie 2016
Creators: name: Migliori, Chiara
Publisher: name: Iperstoria
Year: 2020

description: Nella storia degli Stati Uniti esistono due tipi di fondamentalismo: quello che, seppure inconsciamente in quanto il termine era ancora lontano dall’essere coniato, giunse in America insieme ai puritani e li accompagnò nella fondazione degli insediamenti e nei primi tre secoli di vita delle colonie, e quello che, avendo affrontato le dispute ideologiche che attraversarono il passaggio dal diciannovesimo al ventesimo secolo, poté ottenere una definizione ufficiale e diventare movimento a tutti gli effetti. Nel 1920 Curtis Lee Laws, editore battista del The Watchmen-Examiner definì fondamentalista se stesso e tutti coloro che erano disposti “a intraprendere una lotta all’ultimo sangue per i fondamentali della fede” (Marsden). I fondamentali in questione erano quelli individuati nel 1910 dalla Presbyterian General Assembly: “(1) infallibilità letterale della Bibbia, (2) nascita di Cristo da madre vergine, (3) redenzione attraverso la sua morte sacrificale, (4) resurrezione in corpore di Cristo e (5) autenticità dei miracoli dei Vangeli” (Giammanco 1993, 117). Il fondamentalismo è proprio di chi si erge a difensore della cristianità scontrandosi con chi la vive in maniera più libera e, in ambito protestante, contro la maggior parte degli evangelicali, la cui fede si basa su tre capisaldi: la rinascita in Gesù Cristo, intesa come seconda conversione al Cristianesimo, e la fede in lui come unico mezzo per ottenere la salvezza della propria anima; l’importanza delle Sacre scritture e, infine, l’opera di evangelizzazione, tramite la predicazione della parola di Dio, volta a convertire il maggior numero possibile di persone.
description: Iperstoria, No 6 (2015): La 'realtà' trasnazionale della razza. Dinamiche di razzializzazione in prospettiva comparata
Supplementary document for Photoconductive terahertz generation in semi-insulating GaAs and InP under the extremes of bias field and pump fluence - 4990110.pdf
Creators: name: Alfihed, Salman
name: Jenne, Matthias
name: Ciocoiu, Antonia
name: Foulds, Ian
name: Holzman, Jonathan
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplemental Document
Negative effects of the neonicotinoid clothianidin on foraging behavior and antennal sensitivity in two common pollinator species, osmia bicornis and bombus terrestris
Creators: name: Straub, Florian
name: Orih, Ihotu Joy
name: Kimmich, Judith
name: Ayasse, Manfred
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Osmia bicornis
subject: Bombus terrestris
subject: Clothianidin
subject: Foraging flight
subject: Antennal sensitivity
subject: DDC 570 / Life sciences
subject: DDC 590 / Animals (Zoology)
subject: Neonicotinoids
subject: Antennae (Biology)
subject: Erdhummel

description: Insect species richness and abundance has declined rapidly over the last few decades. Various stressors, such as the conversion of natural habitats, climate change, landuse intensification, agrochemicals and pathogens, are thought to be major factors in this decline. We treated female bees of two common pollinator species in Europe, Osmia bicornis and Bombus terrestris, with a field-realistic dose of the neonicotinoid clothianidin. We tested its effects on the foraging behavior of O. bicornis under seminatural conditions and on the antennal sensitivity of both bee species to common floral volatiles by using electroantennography. Clothianidin negatively affected the foraging behavior in O. bicornis by decreasing the number of flowers visited per foraging flight and by increasing the time per flower visit and the searching time between two flowers. It also decreased the antennal sensitivity to 2-phenylethanol in the two bee species. Thus, clothianidin is clearly a threat for bees via its effects on their foraging behavior and antennal sensitivity and is hence probably detrimental for pollination and the reproductive success of bees.
Development of expert coaches of figure skating.
Creators: name: Laplante, Denise.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Education, Physical.

description: In depth open-ended interviews were conducted with eight World and/or Olympic figure skating coaches across the three disciplines of singles, pairs and ice dancing. The purpose of the interviews was to investigate the development of expertise in figure skating coaches. It was intended on one hand to reveal their knowledge and procedures within the developmental stages of their careers, and secondly to investigate the role of coaching education and other methods by which they acquired their knowledge. The coaches had on average 23.5 years of experience. The results of the present study identified the following stages: early involvement in sport, transitions into coaching, early coaching career, mature coaching career, expert coaching and future retirement. As athletes, with master coaches and parental support, they were able to achieve high levels of success and learned valuable athletic experiences. All coaches had been fourth or better at national championships, more than half had competed internationally, and half had been world championship and/or Olympic competitors. Their transition into coaching had been made for several reasons. (Abstract shortened by UMI.)
title: Viele Begleiterkrankungen bei inzidentem systemischen Lupus erythematodes: Abrechnungsdiagnosen aus Krankenkassendaten
Creators: name: Albrecht, Katinka
name: Redeker, Imke
name: Aringer, Martin
name: Marschall, Ursula
name: Zink, Angela
name: Callhoff, Johanna
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die Autoimmunität beim systemischen Lupus erythematodes (SLE) kann sich gegen eine Vielzahl von Organen richten. Bei inzidentem SLE sind noch keine Begleiterkrankungen zu erwarten, die durch anti-inflammatorische Medikation verursacht werden. Die Fragestellung dieser Arbeit war, welche[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Rheumatologiekongress 2020, 48. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 34. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh)
La cultura selfie in uno stato diviso tra interessi economici e sorveglianza
Creators: name: Giroux, Henry
name: Romanzi, Valentina
Publisher: name: Iperstoria
Year: 2020

description: La sorveglianza è diventata un tratto sempre più comune della vita di tutti i giorni, messa in atto sia dallo stato sia dalla più ampia sfera delle grandi società capitalistiche. Questa fusione registra la trasformazione dello stato politico nello stato controllato dalI’interesse economico e dell’economia di mercato in un’economia criminale. Un crescente attributo della fusione tra gli apparati di sorveglianza dello stato e delle grandi società è la convinzione sempre più marcata, da parte del pubblico americano, che la privacy sia qualcosa da cui sfuggire piuttosto che un prezioso diritto politico da preservare. Lo stato di sicurezza e sorveglianza controllato dagli interessi economici è uno stato che non si limita ad ascoltare, osservare e raccogliere gigantesche quantità di informazioni attraverso l’estrazione dei dati necessari per il monitoraggio del pubblico americano (considerato al contempo come riserva di potenziali terroristi e vasto mercato di consumatori) ma inoltre lo plasma tanto da portarlo ad accettare l’intrusione delle tecnologie di sorveglianza e di valori mercificati privatizzati in tutti gli aspetti della vita. Le informazioni personali sono cedute volontariamente tramite i social media e altri siti governati da interessi economici come Instagram, Facebook, MySpace e altre piattaforme, per poi essere raccolte di giorno in giorno mentre le persone si muovono da un sito sotto controllo all’altro tramite diversi schermi e strumenti digitali. Come evidenzia Ariel Dorfman, “gli utenti dei social media rinunciano volentieri alla propria libertà e alla propria privacy, invariabilmente per la più ipocrita delle banalità e delle ragioni,” mentre nel frattempo fanno acquisti online e mandano messaggi (Dorfman). Nonostante i selfie possano non riguardare direttamente la cessione di importanti informazioni personali online, hanno certamente un ruolo nel mostrare come sia necessario rendere l’io una questione di interesse pubblico, e possono essere una manifestazione di come un’infatuazione per la cultura selfie ora rimpiazzi qualsiasi nozione di socialità, in quanto unica forma di iniziativa personale disponibile a molti. In queste circostanze diventa molto più facile mettere a rischio i diritti alla privacy, dato che sono visti meno come qualcosa da proteggere e più qualcosa da cui fuggire, così da potere mettere in mostra il proprio io.
description: Iperstoria, No 6 (2015): La 'realtà' trasnazionale della razza. Dinamiche di razzializzazione in prospettiva comparata
Profiling apoptotic patterns during forelimb development and regeneration in the newt, Notophthalmus viridescens
Creators: name: Vlaskalin, Tatjana
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Biology, Molecular.

description: Recent studies have found that many of the genes involved in the initial development of the limb in higher vertebrates are also expressed during regeneration of the limb in urodeles. These similarities have lead researchers to conclude that the regeneration process is a recapitulation of development and that patterning of the regenerate mimics pattern formation in development. In this work, we address the issue of whether regeneration and development are similar by examining patterns of apoptosis during these processes. In contrast to higher vertebrates, forelimb development in the newt, Notophthalmus viridescens, does not follow conventional pattern formation utilizing interdigital apoptosis as the method of individualization of the digits. Similarly, forelimb regeneration does not undergo interdigital apoptosis during cartilage condensation and digit formation in the adult. Apoptosis seems to play an important role during the wound healing stage of regeneration and again during cartilage to bone turnover during digit and radius/ulna regeneration. We suggest that urodeles have adapted a mechanism of forelimb regeneration that may re-activate developmental pathways similar to higher vertebrates, yet without cell death between the digits, and furthermore, undergo a unique mechanism of limb development in which apoptosis plays a minor role.
title: Mehrwert von Symptom-Checkern bei der Diagnosestellung von rheumatologischen Erkrankungen
Creators: name: Knitza, Johannes
name: Kaletta, Hannah
name: Krusche, Martin
name: Hagen, Melanie
name: Wacker, Jochen
name: Schett, Georg
name: Simon, David
name: Hueber, Axel
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Rheumatische Erkrankungen sind oft komplex und für Studenten und fachfremde Ärzte schwer diagnostizierbar. Ob hierbei Diagnoseunterstützungssysteme wie „Ada – Deine Gesundheitshelferin“ ([link:https://ada.com/de/*https://ada.com/de/])[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Rheumatologiekongress 2020, 48. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 34. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh)
Supplementary document for Characterization of Deep Sub-wavelength Nanowells by Imaging the Photon State Scattering Spectra - 4990502.pdf
Creators: name: Liu, Weiping
name: Xiong, Jichuan
name: Zhu, Libo
name: Ye, Shengwei
name: Zhao, Hanwen
name: Liu, Juan
name: Zhang, Heng
name: Hou, Lianping
name: Marsh, John
name: Dong, Lei
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary materials
Regulation of the tyrosine phosphatase SHP-1 expression by C-jun-N-terminal kinase and RFX-1 and AP-4 transcription factors in insulin-like growth factor-1 (IGF-1) stimulated breast adenocarcinoma MCF-7 cells
Creators: name: Amin, Shahreen
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Biology, Molecular.
subject: Biology, Microbiology.

description: This thesis is devoted to reveal the negative regulators in IGF-1 (Insulin like growth factor 1) stimulated growth of a human breast adenocarcinoma cell line. It is a well established fact that increased circulating levels of IGF-1 correlate with increased risk of breast cancer. IGF-1 activation of its receptor, IGF-1R, is implicated in the progression of breast cancer, where IGF-1 stimulation leads to proliferative and anti-apoptotic responses by stimulating MAPK Erk and PI3K, respectively. In this study, IGF-1 stimulated MCF-7 cells proliferated more in the absence of MAPK JNK, implicating the involvement of MAPK JNK in the negative regulation of IGF-1 stimulated cell growth. In this research study, we show for the first time that IGF-1 stimulation of breast cancer cells induces SHP-1-expression by activating JNK, which in turn, activates RFX-1 and AP-4 transcription factors to allow them to bind to the high-expression region of the SHP-1 P-1 promoter in breast adenocarcinoma MCF-7 cells. (Abstract shortened by UMI.)
Development and evaluation of a psychoeducation program to reduce family accommodation in relatives of patients experiencing symptoms of obsessive-compulsive disorder
Creators: name: Beeken, Samantha
Publisher: name: Swinburne
Year: 2024

description: This research project was developed to address the lack of treatment options available for family members of those who experience Obsessive-Compulsive Disorder. The development of the Family Accommodation Support Program was based on interviews with family members who shared their experiences of living with someone experiencing OCD and provided suggestions on what they would find useful in a support program. The program was delivered to groups of family members and found to increase knowledge and confidence about managing OCD and understanding family accommodation and to positively impact on quality of life and stress. Recommendations for future programs were also developed.
title: Komorbidität und Inanspruchnahme der Gesundheitsversorgung bei Personen mit Sjögren-Syndrom: eine Analyse von Abrechnungsdaten der GKV
Creators: name: Callhoff, Johanna
name: Dörner, Thomas
name: Redeker, Imke
name: Karberg, Kirsten
name: Marschall, Ursula
name: Zink, Angela
name: Albrecht, Katinka
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Das Sjögren-Syndrom (SS) kann zahlreiche Organe betreffen, darunter die Muskeln, das periphere Nervensystem, die Nieren und die Lunge. Epidemiologische Studien zur Beurteilung der Komorbidität und der Inanspruchnahme der Gesundheitsversorgung sind erforderlich, um die Gesundheitsversorgung[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Rheumatologiekongress 2020, 48. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 34. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh)
Site-specific variations in bone mineral density under systemic conditions inducing osteoporosis in minipigs
Creators: name: Schulz, Matthias Christian
name: Kowald, Jan
name: Estenfelder, Sven
name: Jung, Roland
name: Kuhlisch, Eberhard
name: Eckelt, Uwe
name: Mai, Roland
name: Hofbauer, Lorenz C.
name: Stroszczynski, Christian
name: Stadlinger, Bernd
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: bone
subject: bone mineralization
subject: oral cavity
subject: osteoporosis
subject: DDC 610 / Medicine & health
subject: Osteoporosis
subject: Models, Animal
subject: Bone density
subject: Osteoporose
subject: Knochendichte
subject: Tiermodell

description: Osteoporosis is a systemic bone disease with an increasing prevalence in the elderly population. There is conflicting opinion about whether osteoporosis affects the alveolar bone of the jaws and whether it poses a risk to the osseointegration of dental implants. The aim of the present study was to evaluate the effects of systemic glucocorticoid administration on the jaw bone density of minipigs. Thirty-seven adult female minipigs were randomly divided into two groups. Quantitative computed tomography (QCT) was used to assess bone mineral density BMD of the lumbar spine as well as the mandible and maxilla, and blood was drawn. One group of minipigs initially received 1.0 mg prednisolone per kg body weight daily for 2 months. The dose was tapered to 0.5 mg per kg body weight per day thereafter. The animals in the other group served as controls and received placebo. QCT and blood analysis were repeated after 6 and 9 months. BMD was compared between the two groups by measuring Hounsfield units, and serum levels of several bone metabolic markers were also assessed. A decrease in BMD was observed in the jaws from baseline to 9 months. This was more pronounced in the prednisolone group. Statistically significant differences were reached for the mandible (p < 0.001) and the maxilla (p < 0.001). The administration of glucocorticoids reduced the BMD in the jaws of minipigs. The described model shows promise in the evaluation of osseointegration of dental implants in bone that is compromised by osteoporosis.
title: Identifikation rheumatologisch relevanter gesundheitsbezogener Apps mit der „Semiautomatischen retrospektiven App Store Analyse“ Methode
Creators: name: Richter, Jutta
name: Kiltz, Uta
name: Chehab, Gamal
name: Schneider, Matthias
name: Specker, Christof
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die App-Stores von Apple und Google bieten eine große Anzahl mobiler gesundheitsbezogener Apps für Interessierte an. Seit neuem wird auch Forschung zur Identifizierung, Charakterisierung und Bewertung von gesundheitsbezogenen Apps durchgeführt. Verschiedene Gütesiegel[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Rheumatologiekongress 2020, 48. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 34. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh)
Tutorial on the Universal Variability Language
Creators: name: Sundermann, Chico
name: Feichtinger, Kevin
name: Galindo, José A
name: Benavides, David
name: Rabiser, Rick
name: Krieter, Sebastian
name: Thüm, Thomas
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: variability modeling
subject: product line
subject: feature modeling
subject: UVL
subject: DDC 000 / Computer science, information & general works
subject: Software product line engineering
subject: Software Engineering
subject: Produktlinie

description: The multitude of formats for specifying variability models induces additional effort for researchers and practitioners and hinders exchange. The Universal Variability Language (UVL) is a community effort towards a unified format. Over the last two years, several tools integrated UVL allowing a wide usage. This tutorial consists of three major parts, where we showcase (1) the basics of UVL and how to use it for modeling within FeatureIDE, (2) how to transform other formats to UVL and back with TRAVART, and (3) how to perform feature-model analyses on UVL models with FLAMA.
title: Nutzung einer App zur Erfassung patientenberichteter Parameter – Daten aus dem Schwangerschaftsregister Rhekiss
Creators: name: Richter, Jutta
name: Bungartz, Christina
name: Weiß, Anja
name: Fischer-Betz, Rebecca
name: Zink, Angela
name: Schneider, Matthias
name: Strangfeld, Anja
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Das bundesweite, deutsche Schwangerschaftsregister Rhekiss wurde 2015 als webbasiertes Register implementiert. Es beobachtet Frauen mit entzündlich-rheumatischen Erkrankungen prospektiv vom Kinderwunsch über die Schwangerschaft bis zwei Jahre nach der Geburt. Während der Beobachtung[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Rheumatologiekongress 2020, 48. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 34. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh)
Mathematics in tennis
Creators: name: Clarke, Stephen
Publisher: name: Swinburne
Year: 2024

description: In recent years there has been an increasing interest in the application of mathematics to problems in sport. Students interested in a range of mathematical applications in sports such as baseball, Americann football, basketball, hockey, cricket, tennis, golf, athletics and rowing should read Ladany and machol (1977), 'Optimal Strategies in Sports', North Holland Publ. Co. As an example, we will look at applying some probability to investigate the effects of different scoring systems in tennis... [Introduction]
Increasing Healthy Outcomes for Prostate Cancer Survivors : An Innovative Cooking Class Intervention Feasibility Study ; Study Summary, Archive of Course Curriculum, Recipes, and Photos
Creators: name: Gotay, Carolyn C., 1951-
Publisher: name: The University of British Columbia
Year: 2019

description: Prostate cancer is the most commonly diagnosed cancer in Canadian men, with 1 in 7 men being diagnosed during their lifetime. Survival five years post-diagnosis in men aged 40-79 is more than 95%1; however, post-treatment, many survivors live with the side-effects of the disease and/or treatment and may develop chronic conditions due to aging and/or cancer therapy (e.g., bone loss, weight gain). Nutrition can play a role in preventing some of these side-effects or lessening their impact. Innovative approaches are urgently needed to prevent and mitigate the negative effects of prostate cancer and promote healthy lifestyles in prostate cancer survivors. Given that prostate cancer is a disease that affects not only the patient, but also family members, interventions that Includie both survivors and their partners hold particular promise of benefit. This study tested the feasibility of a novel behavioural approach: cooking classes for prostate cancer survivors and their spouses. The cooking class intervention consisted of six weekly two-hour group cooking classes, led by an educator/chef team. A total of 22 couples participated in the pilot study. All men in the study had been diagnosed with prostate cancer and were living with wife or common law partner. The program had successful accrual, retention, and adherence, with virtually no attrition or drop out. Evaluation data showed that 100% of participants reported that they found the class helpful, and they would recommend it to other men with prostate cancer and their partners. We also found promising outcome data, with analysis of anthropomorphic data showing a reduction in weight and waist and hip circumference for the majority of both survivors and spouses. These positive findings support the importance of replicating and extending this approach in larger populations, and exploring additional ways to provide the curriculum. We hope that such efforts can build on the well-received materials that we developed in this project. To that end, the course curriculum and the session-specific recipes are provided here and can be freely used.
Forschungsbericht der Universität Ulm der Jahre 1993 bis 1995
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Research; Ulm
subject: Universities; Germany; Ulm
subject: Forschungsbericht
subject: Ulm / Universität

description: Forschungsbericht der Universität Ulm der Jahre 1993 bis 1995
Supplementary document for Neural Network Enabled Metasurface Design for Phase Manipulation - 4991306.pdf
Creators: name: Gao, Li
name: Jiang, Li
name: Li, Xiaozhong
name: Wu, Qingxin
name: Wang, Lianhui
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary Information
Mitochondrial proton leak and uncoupling protein expression in transgenic mice and human obesity.
Creators: name: Monemdjou, Shadi.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Biology, Cell.

description: The significance of the uncoupling protein-1 (UCP1) in brown adipose tissue (BAT) thermogenesis has been well defined. However, the absence of significant amounts of BAT in adult humans, and the desire to reveal the mechanisms modulating skeletal muscle thermogenesis, led to the search for other proteins homologous to UCP1 which could also mediate thermogenesis by uncoupling oxidative phosphorylation. This search led to the discovery of Ucp2 and Ucp3 genes, as well as Ucp4 and brain mitochondrial carrier protein-1 (BMCP1). Ucp3 is of particular interest as a potential mediator of thermogenesis because it is selectively expressed at moderately high levels in human skeletal muscle, a tissue that contributes significantly to resting energy expenditure. In this thesis we attempt to elucidate the true physiological role of the UCP1 homologues, and of UCP3 specifically, by examining mitochondrial proton leak and UCP3 protein expression in: (1) mice that do not express Ucp3 ( Ucp3-knockout mice), (2) transgenic mice that overexpress human Ucp3 in their skeletal muscle (UCP-3Tg mice), (3) and finally in a distinct population of women who differ in their rate of weight loss. Our studies with the Ucp3-knockout mice show that the mitochondrial proton conductance is reduced in skeletal muscle mitochondria when UCP3 is absent. This result supports the hypothesis that UCP3 is a significant contributor to proton leak in skeletal muscle, and that the remaining UCPs in muscle (e.g., UCP2) do not compensate for the loss of UCP3. Mice overexpressing human UCP3 in skeletal muscle have total Ucp3 mRNA expression that is 66-fold greater than normal, and despite an increase in food intake, they are more lean than controls. Our results from human studies have provided the first ever measurements of proton leak in human muscle mitochondria. We examined the role of UCP3 and mitochondrial proton leak in patients on an energy restricted diet (900 kcal/day) who were identified as either diet-responsive or diet-resistant. Our results indicate that the state 4 oxygen consumption is 51% higher in the diet-responsive subjects compared to the diet-resistant ones. In addition, Ucp3 mRNA expression was found to be 25% greater in skeletal muscle of diet-responsive compared to diet-resistant individuals, suggesting that the upregulation of this protein could be responsible for the differences seen in the rate of weight loss. (Abstract shortened by UMI.)
title: Daily clinical care of patients with musculoskeletal complaints – how helpful is a triage system for early recognition of inflammatory rheumatic diseases?
Creators: name: Baraliakos, Xenofon
name: Redeker, Imke
name: Zacharopoulou, Maria
name: Tsiami, Styliani
name: Tsiaousi, Konstantia
name: Morzeck, Doris
name: Braun, Jürgen
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Introduction: Early diagnosis and treatment are important for the management of inflammatory rheumatic diseases (RMD). However, the availability of rheumatologists is limited and selection strategies lack sensitivity and/or specificity. We evaluated a triage strategy with the possibility to see[for full text, please go to the a.m. URL]
description: Deutscher Rheumatologiekongress 2020, 48. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 34. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh)
A dynamic model of the token bucket control mechanism in computer networks.
Creators: name: Wang, Qun.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Engineering, Electronics and Electrical.

description: In order to provide Quality of Service (QoS), the network must enforce traffic management such as traffic classification, admission control, access control (shaping and policing), flow control and congestion control. Applying the policies and mechanisms of traffic management, the Internet Engineering Task Force (IETF) has proposed various QoS models, Integrated Service (IntServ), Differentiated Service (DiffServ) and Multiple Protocol Label Switching (MPLS), for the next-generation Internet in order to deliver emerging multimedia applications, which have stringent QoS requirements. It is interesting to note that the Token Bucket (TB) algorithm as a control mechanism has been employed popularly in them. In this thesis, we construct a new dynamic model for the TB control mechanism and apply a system approach to its analysis. This model is then augmented by adding a dynamic model of a multiplexer in an access node, where the TB exercises a policing function. In the model, traffic policing, traffic multiplexing and network utilization are formally defined. Based on the model, the issues such as QoS, traffic sizing and network dimensioning are studied. And also we propose an algorithm using feedback control to improve QoS and network utilization. Applying MPEG video traces as the input traffic to the model, the numerical computing results very much agree to the analytical model. The model gives a guideline to study the interactions among the traffics and elements of TB-based access control to achieve desired QoS and network utilization.
Das Kartenhaus Weltfinanzsystem - die Krise als Chance für eine nachhaltige Zukunft
Creators: name: Solte, Dirk
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 320 / Political science
subject: Money policy (Currency questions); Europe
subject: Money; Europe
subject: Finanzkrise
subject: Internationaler Kreditmarkt
subject: Online-Publikation
subject: Ringvorlesung

description: Das Kartenhaus Weltfinanzsystem - die Krise als Chance für eine nachhaltige Zukunft. Globale Probleme brauchen zur Lösung ein abgestimmtes globales Handeln. Der Vortrag erklärt in verständlicher Weise, was Geld ist und wie das Weltfinanzsystem funktioniert(e), und zeigt auf, wie die dortigen Probleme mit den Umwelt- und Sozialproblemen auf der Erde zusammen hängen. Mit einem konkreten Lösungsweg wird aufgezeigt, dass eine "Welt in Balance" möglich ist. Hat die Politik den richtigen Weg eingeschlagen? Wie ist die Situation in und die Rolle von Europa?