cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Test Benches for testing detecting materials in picosecond and sub-picosecond domains
Creators: name: N. Kratochwil
name: F. Pagano
name: E. Auffray
name: V. Babin
name: J. Vitezslav
name: M. Nikl
name: G. Tamulaitis
name: S. Nargelas
name: A. Vaitkevicius
name: C. Cecchi
name: G. De Nardo
name: E. Manoni
name: M. Merola
name: S. Moneta
name: L. Bandiera,
name: M. Moulson
name: N. Pastrone
name: I. Sarra
Publisher: name: Zenodo
Year: 2022
Subjects: WP8

description: For characterization of the fast timing properties of scintillating materials, several test benches have been developed and commissioned in various institutes within WP8 task 8.3.1 such as time resolved spectroscopy with pulsed Xrays, time coincidence resolution, pump and probe, test beam set-up for assessing the timing performances using high energy particles in beam tests. A description of the different benches is given in this document.
title: Reliability of single slice measurement of skeletal muscle surface area and psoas muscle surface area on CT imaging used in clinical practice
Creators: name: Weerink, Linda
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Abdomen
subject: CT
subject: Computer Applications-General
subject: Cancer
subject: Outcomes

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Low skeletal muscle mass is associated with increased risk of postoperative complications in surgical oncology. At present there is no consensus on the preferred method of measuring skeletal muscle mass or cut-off values for defining patients with...
Computational approaches to understanding protein aggregation in neurodegeneration
Creators: name: Dagliyan, O.
name: Tandon, A.
name: Proctor, E. A.
name: Redler, R. L.
name: Kim, D. N.
name: Ding, F.
name: Ramachandran, S.
name: Kota, P.
name: Shirvanyants, D.
name: Dokholyan, N. V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The generation of toxic non-native protein conformers has emerged as a unifying thread among disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. Atomic-level detail regarding dynamical changes that facilitate protein aggregation, as well as the structural features of large-scale ordered aggregates and soluble non-native oligomers, would contribute significantly to current understanding of these complex phenomena and offer potential strategies for inhibiting formation of cytotoxic species. However, experimental limitations often preclude the acquisition of high-resolution structural and mechanistic information for aggregating systems. Computational methods, particularly those combine both all-atom and coarse-grained simulations to cover a wide range of time and length scales, have thus emerged as crucial tools for investigating protein aggregation. Here we review the current state of computational methodology for the study of protein self-assembly, with a focus on the application of these methods toward understanding of protein aggregates in human neurodegenerative disorders.
title: Stellungnahme zum Zentrum für Luft- und Raumfahrtmedizin der Luftwaffe (ZentrLuRMedLw), Köln
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2023
Subjects: Ressortforschung
Evaluation
Medizin
Forschungseinrichtungen
Klinische Forschung
ressortübergreifende Finanzierung
DLR

description: Das Zentrum für Luft- und Raumfahrtmedizin der Luftwaffe erbringt unverzichtbare Leistungen auf allen wesentlichen Aufgabengebieten der Luft- und Raumfahrtmedizin. Es führt gute bis sehr gute anwendungsorientierte Forschung durch und trägt mit seinen forschungsbasierten Dienstleistungen zu einer verbesserten Einsatzfähigkeit von Pilotinnen und Piloten sowie zur Optimierung der Flugsicherheit bei. Besonders begrüßt der Wissenschaftsrat die Zusammenarbeit der militärischen Einrichtung mit dem zivilen Deutschen Zentrum für Luft- und Raumfahrt (DLR) in Köln.
title: Stellungnahme zur Bundesanstalt für Wasserbau (BAW), Karlsruhe
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2023
Subjects: Ressortforschung
Evaluation
Forschungseinrichtungen
Forschungsinfrastrukturen
Wasserbau
Wasserstraßeninfrstruktur
Binnenschifffahrt

description: Die Bundesanstalt für Wasserbau (BAW) forscht zum Erhalt und Ausbau der wasserbaulichen Infrastruktur und zur nachhaltigen Weiterentwicklung der Wasserstraßen. Ihre Forschungserkenntnisse sind Grundlage für die Beratung des Bundesministeriums für Digitales und Verkehr (BMDV) sowie der Wasserstraßen- und Schifffahrtsverwaltung des Bundes (WSV) und angesichts der Bedeutung der Binnenschifffahrt für die Verkehrswende von großer Relevanz. Der Wissenschaftsrat hebt die sehr positive Entwicklung der BAW hervor und empfiehlt der Einrichtung, ihre einzigartigen Forschungsinfrastrukturen und ihre große Methodenkompetenz noch stärker für die wissenschaftliche Fachgemeinschaft zu öffnen.
title: Cardiac MR in Pneumoconiosis
Creators: name: Bhatia, Mona
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Toxicity
subject: Tissue characterisation
subject: Occupational / Environmental hazards
subject: Screening
subject: Health policy and practice
subject: Education
subject: MR-Functional imaging
subject: MR
subject: CT
subject: Respiratory system
subject: Lung
subject: Cardiac

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The learning objective is to demonstrate the cardiac complications of complicated pulmonary silicosis with extra-pulmonary...
High Granularity Prototype Fabrication 1
Creators: name: Wermes, Norbert
name: Huegging, Fabian
name: Grinstein, Sebastian
Publisher: name: Zenodo
Year: 2022
Subjects: WP5

description: Within WP5 (Development of Monolithic Active Pixel Sensors) Milestone MS18 contains the fabrication of several prototypes.
 This milestone has been successfully achieved and is reported.
title: Umsetzung der Empfehlungen aus der zurückliegenden Evaluation des Hannah-Arendt-Instituts für Totalitarismusforschung e.V. (HAIT), Dresden
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2023
Subjects: Evaluation
Forschungseinrichtungen
Diktaturforschung
Extremismusforschung
Transformationsforschung
NS-Diktatur
Geschichtswissenschaft

description: Der Wissenschaftsrat begrüßt, dass das Institut und der Freistaat Sachsen seine Empfehlungen großenteils umgesetzt haben. Er würdigt insbesondere die begonnene Neustrukturierung des Forschungsprogramms, die dem Institut zu einer stärkeren Fokussierung und flexiblen Einsatzmöglichkeiten für das wissenschaftliche Personal verhilft, und die Erhöhung des Institutshaushalts, die trotz der durch Pandemie und den russischen Angriffskrieg auf die Ukraine bedingten Krisenlage erzielt werden konnte. In einigen Fällen bekräftigt der Wissenschaftsrat seine Empfehlungen, insbesondere im Hinblick auf die Erarbeitung einer Digitalisierungsstrategie und die Weiterentwicklung der am HAIT vorhandenen Datenbanken sowie die Einrichtung einer Stelle für IT-Betreuung.
Ground state, magnetization process and magnetocaloric effect of the exactly tractable spin-electron tetrahedral chain
Creators: name: Gálisová, Lucia
name: Strečka, Jozef
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: A hybrid spin-electron system on one-dimensional tetrahedral chain, in which the localized Ising spin regularly alternates with the mobile electron delocalized over three lattice sites, is exactly investigated using the generalized decoration-iteration transformation. The system exhibits either the ferromagnetic or antiferromagnetic ground state depending on whether the ferromagnetic or antiferromagnetic interaction between the Ising spins and mobile electrons is considered. The enhanced magnetocaloric effect during the adiabatic demagnetization suggests a potential use of the investigated system for low-temperature magnetic refrigeration.
description: 3 pages, 4 figures, contribution to proceedings of The European Conference PHYSICS OF MAGNETISM 2014 (PM'14) in Poznan, Poland
Current Situation and Countermeasures of Platycodon grandiflorus Industry Development in Shandong Province
Creators: name: WANG, Shaoshan
name: SUN, Lixin
name: SHAN, Yu
name: HAN, Hongfeng
name: WANG, Shaoshan
name: SUN, Lixin
name: SHAN, Yu
name: HAN, Hongfeng
Publisher: name: Unknown
Year: 2022
Subjects: subject: Agribusiness
subject: Platycodon grandiflorus; Current situation; Problem; Countermeasures

description: In order to promote the green, healthy and sustainable development of Platycodon grandiflorus industry, the current situations of P. grandiflorus industry development in Shandong Province were analyzed. That is, an advantageous area has been gradually formed; product processing is diversified; industrialization development pattern is gradually emerging. The three problems in the development of P. grandiflorus industry were deeply analyzed. That is, it is difficult to control product quality; the problem of soil obstacles to continuous cropping is serious; the problem of talent shortage is prominent. Four countermeasures for the next development were put forward as follows: increasing government support, strengthening the construction of talent team, implementing crop rotation or intercropping, and increasing technology promotion.
title: Imaging of branchial cleft cysts and fistulas
Creators: name: mlouka, ahmed
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Ear / Nose / Throat
subject: Head and neck
subject: CT
subject: Ultrasound
subject: MR
subject: Surgery
subject: Endoscopy
subject: Congenital
subject: Cysts
subject: Fistula

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Branchial cleft anomalies result from abnormal persistence of branchial apparatus, which is located at the lateral part of the neck. They represent the 2 nd most common pathological malformation of the face and neck They may present as cysts, sinus...
title: Stellungnahme zur Institutionellen Reakkreditierung (Promotionsrecht) der Kühne Logistics University, Hamburg
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2023
Subjects: Akkreditierung
Promotion
Qualitätssicherung
Private Hochschulen
Hochschulförmigkeit
Akkreditierungszeitraum 5 plus 5 Jahre

description: Die Kühne Logistics University (KLU) wurde im Jahr 2010 gegründet und ist vom Land Hamburg als private Hochschule unbefristet staatlich anerkannt. Seit 2017 verfügt sie über das befristete Promotionsrecht. Betreiberin und alleinige Gesellschafterin der Trägereinrichtung ist die Kühne-Stiftung mit Sitz in der Schweiz. Die KLU bietet ihren derzeit rund 360 Studierenden fünf Bachelor- und Masterstudiengänge in den Bereichen Logistik und Unternehmensführung an. Hinzu kommt ein strukturiertes Promotionsprogramm, in das im Wintersemester 2022/23 rund 60 Doktorandinnen und Doktoranden eingeschrieben waren. Im gleichen Zeitraum beschäftige die KLU hauptberufliche Professorinnen und Professoren in einem Umfang von rd. 26 VZÄ (inkl. Hochschulleitung).
title: Post-pancreatitis fat saponification imitating carcinomatosis
Creators: name: Regaña Feijoó, María José
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Abdomen
subject: Pancreas
subject: Oncology
subject: CT
subject: Diagnostic procedure
subject: Image compression
subject: Acute
subject: Inflammation
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review the physiopathology and radiological findings characteristic of the phenomenon of fatty saponification associated with acute pancreatitis. To establish the keys for its differential diagnosis with peritoneal carcinomatosis, due to the...
G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection
Creators: name: Barrick, C. J.
name: Leeb-Lundberg, L. M. F.
name: Lenhart, P. M.
name: Broselid, S.
name: Caron, K. M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Receptor activity modifying protein 3 (RAMP3) is a single pass transmembrane protein known to interact with and affect the trafficking of several G-protein coupled receptors (GPCRs). We sought to determine whether RAMP3 interacts with G-protein coupled receptor 30 (GPR30), also known as G-protein estrogen receptor 1 (GPER1). GPR30 is a GPCR that binds estradiol and has important roles in cardiovascular and endocrine physiology. Utilizing bioluminescence resonance energy transfer titration studies, co-immunoprecipitation, and confocal microscopy, we show that GPR30 and RAMP3 interact. Furthermore, the presence of GPR30 leads to increased expression of RAMP3 at the plasma membrane in HEK293 cells. In vivo, there are marked sex differences in the subcellular localization of GPR30 in cardiac cells, and the hearts of Ramp3−/− mice also show signs of GPR30 mislocalization. To determine whether this interaction might play a role in cardiovascular disease, we treated Ramp3+/+ and Ramp3−/− mice on a heart disease-prone genetic background with G-1, a specific agonist for GPR30. Importantly, this in vivo activation of GPR30 resulted in a significant reduction in cardiac hypertrophy and perivascular fibrosis that is both RAMP3- and sex-dependent. Our results demonstrate that GPR30-RAMP3 interaction has functional consequences on the localization of these proteins both in vitro and in vivo, and that RAMP3 is required for GPR30-mediated cardioprotection.
Beneficial Fitness Effects Are Not Exponential for Two Viruses
Creators: name: Joyce, Paul
name: Ferris, Martin T.
name: Burch, Christina L.
name: Wichman, Holly A.
name: Beisel, Craig J.
name: Rokyta, Darin R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The distribution of fitness effects for beneficial mutations is of paramount importance in determining the outcome of adaptation. It is generally assumed that fitness effects of beneficial mutations follow an exponential distribution, for example, in theoretical treatments of quantitative genetics, clonal interference, experimental evolution, and the adaptation of DNA sequences. This assumption has been justified by the statistical theory of extreme values, because the fitnesses conferred by beneficial mutations should represent samples from the extreme right tail of the fitness distribution. Yet in extreme value theory, there are three different limiting forms for right tails of distributions, and the exponential describes only those of distributions in the Gumbel domain of attraction. Using beneficial mutations from two viruses, we show for the first time that the Gumbel domain can be rejected in favor of a distribution with a right-truncated tail, thus providing evidence for an upper bound on fitness effects. Our data also violate the common assumption that small-effect beneficial mutations greatly outnumber those of large effect, as they are consistent with a uniform distribution of beneficial effects.
title: Radiotracers in hybrid imaging. Review
Creators: name: Grigoryan, Marine
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Cancer
subject: Education
subject: PET-CT
subject: Hybrid Imaging

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1.Recognise what is radiotracer 2.Discuss the different tracers 3.Recognise molecular mechanism of each tracer 4.Discuss their...
title: Imaging of esophageal tuberculosis
Creators: name: Kulikova, Anna
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Decision analysis
subject: Computer Applications-General
subject: Barium meal
subject: Fluoroscopy
subject: Digital radiography
subject: CT
subject: Thorax
subject: Gastrointestinal tract
subject: Chronic obstructive airways disease
subject: Infection

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The purpose of this educational exhibit is to describe and illustrate specific radiological changesin patients with esophageal tuberculosis; present our experience in studying such patients within last 5...
title: Stellungnahme zur Institutionellen Reakkreditierung der AKAD Hochschule Stuttgart
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2023
Subjects: Akkreditierung
Hochschulförmigkeit
Qualitätssicherung
Private Hochschulen
Fernhochschulen
Akkreditierungszeitraum 5 plus 5 Jahre

description: Die AKAD Hochschule wird unter Auflagen für fünf Jahre reakkreditiert. Die AKAD geht auf die 1959 gegründete Akademikergesellschaft für Erwachsenenbildung zurück und wurde 1991 erstmals als Fachhochschule befristet staatlich anerkannt. Sie bietet ihren rd. 6.100 Studierenden rd. 60 Bachelor- und Masterstudiengänge im Fernlehrformat in den Bereichen Wirtschaft, Kommunikation, Technik und Gesundheit an.
On Primordial Sense–Antisense Coding
Creators: name: Carter, Charles W.
name: Rodin, Sergei N.
name: Rodin, Andrei S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: The genetic code is implemented by aminoacyl-tRNA synthetases (aaRS). These twenty enzymes are divided into two classes that, despite performing same functions, have nothing common in structure. The mystery of this striking partition of aaRSs might have been concealed in their sterically complementary modes of tRNA recognition that, as we have found recently, protect the tRNAs with complementary anticodons from confusion in translation. This finding implies that, in the beginning, life increased its coding repertoire by the pairs of complementary codons (rather than one-by-one) and used both complementary strands of genes as templates for translation. The class I and class II aaRSs may represent one of the most important examples of such primordial sence-antisence (SAS) coding (Rodin and Ohno, 1995). In this report, we address the issue of SAS coding in a wider scope. We suggest a variety of advantages that such coding would have had in exploring a wider sequence space before translation became highly specific. In particular, we confirm that in Achylia klebsiana a single gene might have originally coded for an HSP70 chaperonin (class II aaRS homolog) and an NAD-specific GDH-like enzyme (class I aaRS homolog) via its sense and antisense strands. Thus, in contrast to the conclusions in (Williams et al., 2009), this could indeed be a “Rosetta stone” (eroded somewhat, though) gene for the SAS origin of the two aaRS classes (Carter and Duax, 2002).
A Katznelson-Tzafriri theorem for measures
Creators: name: Seifert, David
Publisher: name: arXiv
Year: 2014
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: This article generalises the well-known Katznelson-Tzafriri theorem for a $C_0$-semigroup $T$ on a Banach space $X$, by removing the assumption that a certain measure in the original result be absolutely continuous. In an important special case the rate of decay is quantified in terms of the growth of the resolvent of the generator of $T$. These results are closely related to ones obtained recently in the Hilbert space setting by Batty, Chill and Tomilov in [6]. The main new idea is to incorporate an assumption on the non-analytic growth bound $ζ(T)$ which is equivalent to the assumption made in [6] if $X$ is a Hilbert space.
description: 17 pages, to appear in Journal of Integral Equations and Operator Theory
More Bang For Your Buck: Quorum-Sensing Capabilities Improve the Efficacy of Suicidal Altruism
Creators: name: Johnson, Anya Elaine
name: Strauss, Eli
name: Pickett, Rodney
name: Adami, Christoph
name: Dworkin, Ian
name: Goldsby, Heather J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Within the context of evolution, an altruistic act that benefits the receiving individual at the expense of the acting individual is a puzzling phenomenon. An extreme form of altruism can be found in colicinogenic E. coli. These suicidal altruists explode, releasing colicins that kill unrelated individuals, which are not colicin resistant. By committing suicide, the altruist makes it more likely that its kin will have less competition. The benefits of this strategy rely on the number of competitors and kin nearby. If the organism explodes at an inopportune time, the suicidal act may not harm any competitors. Communication could enable organisms to act altruistically when environmental conditions suggest that that strategy would be most beneficial. Quorum sensing is a form of communication in which bacteria produce a protein and gauge the amount of that protein around them. Quorum sensing is one means by which bacteria sense the biotic factors around them and determine when to produce products, such as antibiotics, that influence competition. Suicidal altruists could use quorum sensing to determine when exploding is most beneficial, but it is challenging to study the selective forces at work in microbes. To address these challenges, we use digital evolution (a form of experimental evolution that uses self-replicating computer programs as organisms) to investigate the effects of enabling altruistic organisms to communicate via quorum sensing. We found that quorum-sensing altruists killed a greater number of competitors per explosion, winning competitions against non-communicative altruists. These findings indicate that quorum sensing could increase the beneficial effect of altruism and the suite of conditions under which it will evolve.
description: 8 pages, 8 figures, ALIFE '14 conference
title: Stellungnahme zur Institutionellen Akkreditierung der Dualen Hochschule Schleswig-Holstein (DHSH), Kiel
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2023
Subjects: Akkreditierung
Hochschulförmigkeit
Qualitätssicherung
Private Hochschulen
dual
Akkreditierungszeitraum 3 Jahre

description: Die Duale Hochschule Schleswig-Holstein (DHSH) wird unter Auflagen für drei Jahre akkreditiert. Sie geht auf die im Jahr 1974 gegründeten Berufsakademie Schleswig-Holstein zurück und nahm ihren Studienbetrieb als Fachhochschule 2018 auf. Sie ist befristet staatlich anerkannt. Ihren rd. 520 Studierenden bietet sie zwei duale ausbildungs- und praxisorientierte Bachelorstudiengänge in Wirtschaftsinformatik und Betriebswirtschaftslehre sowie einen Masterstudiengang an.
Binary frequency of planet-host stars at wide separations: A new brown dwarf companion to a planet-host star
Creators: name: Lodieu, N.
name: Perez-Garrido, A.
name: Bejar, V. J. S.
name: Gauza, B.
name: Ruiz, M. T.
name: Rebolo, R.
name: Pinfield, D. J.
name: Martin, E. L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The aim of the project is to improve our knowledge on the multiplicity of planet-host stars at wide physical separations. We cross-matched approximately 6200 square degree area of the Southern sky imaged by the Visible Infrared Survey Telescope for Astronomy (VISTA) Hemisphere Survey (VHS) with the Two Micron All Sky Survey (2MASS) to look for wide common proper motion companions to known planet-host stars. We complemented our astrometric search with photometric criteria. We confirmed spectroscopically the co-moving nature of seven sources out of 16 companion candidates and discarded eight, while the remaining one stays as a candidate. Among these new wide companions to planet-host stars, we discovered a T4.5 dwarf companion at 6.3 arcmin (~9000 au) from HIP70849, a K7V star which hosts a 9 Jupiter mass planet with an eccentric orbit. We also report two new stellar M dwarf companions to one G and one metal-rich K star. We infer stellar and substellar binary frequencies for our complete sample of 37 targets of 5.4+/-3.8% and 2.7+/-2.7% (1 sigma confidence level), respectively, for projected physical separations larger than ~60-160 au assuming the range of distances of planet-host stars (24-75 pc). These values are comparable to the frequencies of non planet-host stars. We find that the period-eccentricity trend holds with a lack of multiple systems with planets at large eccentricities (e > 0.2) for periods less than 40 days. However, the lack of planets more massive than 2.5 Jupiter masses and short periods (<40 days) orbiting single stars is not so obvious due to recent discoveries by ground-based transit surveys and space missions.
description: Accepted for publication in A&A, 13 pages, 5 figures, 3 tables, optical spectra will be available at CDS Strasbourg
Barriers and support to the inclusion of deaf and hard-of-hearing students in visual art higher education in India
Creators: name: Athaley, Vaibhao Govindrao
name: Mishra, Anindya Jayanta
name: Gupta, Ila
Publisher: name: Academia
Year: 2023
Subjects: deaf and hard-of-hearing, visual arts, higher education, teaching and learning, inclusive education

description: Academic research has paid minimal attention to the experiences of deaf and hard-of-hearing students in visual arts higher education programmes and is yet to be studied in the Indian context. This qualitative study aims to identify barriers and supports deaf and hard-of-hearing students’ perceptions of a visual art higher education programme in India. Individual interviews with the assistance of a qualified sign language interpreter were conducted with 15 deaf and hard-of-hearing students at a public institute. This study highlights the experiences related to the visual art curriculum, interactions, and support services to provide a comprehensive view of their teaching and learning needs. When analysing the data through thematic analysis, the findings show that communication barriers and scarcity of support services impact deaf and hard-of-hearing students’ access to various learning situations among visual art studio and theory subjects. Recognising the efforts in India to build inclusive practices in higher education institutions, it is crucial to be aware of the learning needs of deaf and hard-of-hearing students and provide suitable accommodations. Modifications in curriculum and teaching strategies, providing adequate support services, and sensitisation of teachers and students at educational institutes are possible strategies to develop inclusive visual arts higher education programmes.
description: Academia, Αρ. 33 (2023)
CoMFA analyses of C-2 position Salvinorin A analogs at the kappa-opioid receptor provides insights into epimer selectivity
Creators: name: McGovern, Donna L.
name: Westkaemper, Richard B.
name: Mosier, Philip D.
name: Roth, Bryan L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The highly potent and kappa-opioid receptor (KOR)-selective hallucinogen salvinorin A and selected analogs have been analyzed using the 3D quantitative structure-affinity relationship technique Comparative Molecular Field Analysis (CoMFA) in an effort to derive a statistically significant and predictive model of salvinorin affinity at the KOR and to provide additional statistical support for the validity of previously proposed structure-based interaction models. Two CoMFA models of salvinorin A analogs substituted at the C-2 position are presented. Separate models were developed based on the radioligand used in the kappa-opioid binding assay, [3H]diprenorphine or [125I]6β-iodo-3,14-dihydroxy-17-cyclopropylmethyl-4,5α-epoxymorphinan ([125I]IOXY). For each dataset, three methods of alignment were employed: a receptor-docked alignment derived from the structure-based docking algorithm GOLD, another from the ligand-based alignment algorithm FlexS, and a rigid realignment of the poses from the receptor-docked alignment. The receptor-docked alignment produced statistically superior results compared to either the FlexS alignment or the realignment in both datasets. The [125I]IOXY set (Model 1) and [3H]diprenorphine set (Model 2) gave q2 values of 0.592 and 0.620, respectively, using the receptor-docked alignment, and both models produced similar CoMFA contour maps that reflected the stereoelectronic features of the receptor model from which they were derived. Each model gave significantly predictive CoMFA statistics (Model 1 PSET r2 = 0.833; Model 2 PSET r2 = 0.813). Based on the CoMFA contour maps, a binding mode was proposed for amine-containing salvinorin A analogs that provides a rationale for the observation that the β-epimers (R-configuration) of protonated amines at the C-2 position have a higher affinity than the corresponding β-epimers (S-configuration).
Bien-être et performances académiques des étudiants de l’Université de Kinshasa
Creators: name: Mwenzi, Jonathan Enguta
name: Mokuba, Hera Mbo
name: Moseseli, Giscard Mpangi
name: Nassy, Nassy Mutunga
Publisher: name: Academia
Year: 2023
Subjects: University well-being, academic performance, academic satisfaction, students, University of Kinshasa.

description: The aim of this study was to relate university well-being to the academic performance of final-year students at the University of Kinshasa (Democratic Republic of Congo). To this end, the university well-being and satisfaction scales were administered to a non-probabilistic sample of 250 finalist students of the second cycle, of some faculties, of the University of Kinshasa enrolled for the academic year 2020-2021. The academic performance was obtained from the ranking of points, of the 2020-2021 academic year from some faculties targeted in the study. The results reveal, overall, that the subjects surveyed have a real sense of well-being at the university and are satisfied with their training environment. In addition, the study subjects perform well academically. The multiple regression analysis revealed, the positive and significant effect of well-being at the university on the academic performance of students at the University of Kinshasa. At the level of different dimensions of well-being at the University, the simple linear regression analysis revealed that only four dimensions (relations with the teacher, academic activities, feeling of security and peer relations) out of the seven of well-being and satisfaction positively and significantly influence the academic performance of the students at the University of Kinshasa.
description: Academia, Αρ. 33 (2023)
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) overexpression in human colorectal cancer
Creators: name: Ørntoft, Torben F.
name: Mansilla, Francisco
name: Lewin, Tal M.
name: Coleman, Rosalind A.
name: da Costa, Kerry-Ann
name: Kruhøffer, Mogens
name: Birkenkamp-Demtröder, Karin
name: Wang, Shuli
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: The alteration of the choline metabolite profile is a well-established characteristic of cancer cells. In colorectal cancer (CRC), phosphatidylcholine is the most prominent phospholipid. In the present study, we report that lysophosphatidylcholine acyltransferase 1 (LPCAT1; {"type":"entrez-nucleotide","attrs":{"text":"NM_024830.3","term_id":"33946290","term_text":"NM_024830.3"}}NM_024830.3), the enzyme that converts lysophosphatidylcholine into phosphatidylcholine, was highly overexpressed in colorectal adenocarcinomas when compared to normal mucosas. Our microarray transcription profiling study showed a significant (p<10−8) transcript overexpression in 168 colorectal adenocarcinomas when compared to ten normal mucosas. Immunohistochemical analysis of colon tumors with a polyclonal antibody to LPCAT1 confirmed the upregulation of the LPCAT1 protein. Overexpression of LPCAT1 in COS7 cells localized the protein to the endoplasmic reticulum and the mitochondria and increased LPCAT1 specific activity 38-fold. In cultured cells, overexpressed LPCAT1 enhanced the incorporation of [14C]palmitate into phosphatidylcholine. COS7 cells transfected with LPCAT1 showed no growth rate alteration, in contrast to the colon cancer cell line SW480, which significantly (p<10−5) increased its growth rate by 17%. We conclude that LPCAT1 may contribute to total choline metabolite accumulation via phosphatidylcholine remodeling, thereby altering the CRC lipid profile, a characteristic of malignancy.
title: The Relationship between Absence Coronary Artery Calcification and Myocardial Perfusion Single Photon Emission Computed Tomography.
Creators: name: Fathala, Ahmed
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Outcomes analysis
subject: Image compression
subject: CT
subject: Nuclear medicine conventional
subject: SPECT
subject: Nuclear medicine
subject: Cardiac
subject: Calcifications / Calculi

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Coronary artery calcification score (CACS), is a well validated prognostic tool in coronary artery disease (CAD) Coronary artery calcification (CAC) is an early marker of atherosclerosis and usually precedes the development of CAD by many years Most...
Detection of the dc inverse spin Hall effect due to spin pumping in a novel meander-stripline geometry
Creators: name: Weiler, Mathias
name: Shaw, Justin M.
name: Nembach, Hans T.
name: Silva, Thomas J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The dc voltage obtained from the inverse spin Hall effect (iSHE) due to spin pumping in ferromagnet/normal-metal (NM) bilayers can be unintentionally superimposed with magnetoresistive rectification of ac charge currents in the ferromagnetic layer. We introduce a geometry in which these spurious rectification voltages vanish while the iSHE voltage is maximized. In this geometry, a quantitative study of the dc iSHE is performed in a broad frequency range for Permalloy/NM multilayers with NM={Pt, Ta, Cu/Au, Cu/Pt}. The experimentally recorded voltages can be fully ascribed to the iSHE due to spin pumping. Furthermore we measure a small iSHE voltage in single CoFe thin films.
title: OCULAR SONOGRAPHY: Supporting the ophthalmologist.
Creators: name: Pozo Piñon, Francisco
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Eyes
subject: Anatomy
subject: Head and neck
subject: Ultrasound
subject: Ultrasound-Colour Doppler
subject: Education
subject: Trauma
subject: Inflammation
subject: Cancer

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Explain the technique of ocular ultrasound, the main indications, and the advantages and disadvantages of its use. Also we will review the anatomic characteristics of the eye and the orbit, the most frequent pathologies seen with ultrasound, and see...
A computational modeling and molecular dynamics study of the Michaelis complex of human protein Z-dependent protease inhibitor (ZPI) and factor Xa (FXa)
Creators: name: Chandrasekaran, Vasudevan
name: Duke, Robert E.
name: Lin, Ping
name: Pedersen, Lee G.
name: Lee, Chang Jun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Protein Z-dependent protease inhibitor (ZPI) and antithrombin III (AT3) are members of the serpin superfamily of protease inhibitors that inhibit factor Xa (FXa) and other proteases in the coagulation pathway. While experimental structural information is available for the interaction of AT3 with FXa, at present there is no structural data regarding the interaction of ZPI with FXa, and the precise role of this interaction in the blood coagulation pathway is poorly understood. In an effort to gain a structural understanding of this system, we have built a solvent equilibrated three-dimensional structural model of the Michaelis complex of human ZPI/FXa using homology modeling, protein–protein docking and molecular dynamics simulation methods. Preliminary analysis of interactions at the complex interface from our simulations suggests that the interactions of the reactive center loop (RCL) and the exosite surface of ZPI with FXa are similar to those observed from X-ray crystal structure-based simulations of AT3/FXa. However, detailed comparison of our modeled structure of ZPI/FXa with that of AT3/FXa points to differences in interaction specificity at the reactive center and in the stability of the inhibitory complex, due to the presence of a tyrosine residue at the P1 position in ZPI, instead of the P1 arginine residue in AT3. The modeled structure also shows specific structural differences between AT3 and ZPI in the heparin-binding and flexible N-terminal tail regions. Our structural model of ZPI/FXa is also compatible with available experimental information regarding the importance for the inhibitory action of certain basic residues in FXa.
Statistics of Dark Matter Halos in the Excursion Set Peak Framework
Creators: name: Lapi, A.
name: Danese, L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We derive approximated, yet very accurate analytical expressions for the abundance and clustering properties of dark matter halos in the excursion set peak framework; the latter relies on the standard excursion set approach, but also includes the effects of a realistic filtering of the density field, a mass-dependent threshold for collapse, and the prescription from peak theory that halos tend to form around density maxima. We find that our approximations work excellently for diverse power spectra, collapse thresholds and density filters. Moreover, when adopting a cold dark matter power spectra, a tophat filtering and a mass-dependent collapse threshold (supplemented with conceivable scatter), our approximated halo mass function and halo bias represent very well the outcomes of cosmological $N-$body simulations.
description: 21 pages, 6 figures. Accepted by JCAP
Le relazioni degli esploratori portoghesi e il Mapa Cor-de-Rosa: proposta per una cartografia dell'immaginario africano fin-de siècle
Creators: name: Peretti, Marco
Publisher: name: Universita degli studi di Salerno
Year: 2013
Subjects: subject: L-LIN/08 LETTERATURA PORTOGHESE E BRASILIANA
subject: Esploratori
subject: Portogallo
subject: Cartografia

description: 2010 - 2011
description: This work shows how some reports drawn up by the late nineteenth century Portuguese explorers have contributed to the effort to carry out the project of the colonial Mapa cor-de-rosa (mapping simulation of sovereignty claims over the territories of Portugal located between Angola and Mozambique), thus disproving the myth of an explorer guided exclusively by scientific issues and knowledge desire. Through an historical and dialectical approach we tried to show how the scientific data are not the determining cause of these publications, to which literary critics have always shown little interest because of their alleged "scientific base", and defining them such as para-literature. The analysis of these texts, in comparison with the different literary genres from which the explorers derive from, a part from proving the continuation of some mental positivist coordinates which lead to a renewed commitment on the “other” and on the “elsewhere” seen as the Self-west convoluted logical-historical antecedents, reveal on the contrary the presence of a high rate of literariness that makes them, even for their perlocutionary value, similar to adventure novels rather than scientificacademic treaties. [edited by Author]
description: Questo lavoro mostra come alcuni resoconti di fine Ottocento elaborati dagli esploratori portoghesi abbiano contribuito al tentativo di realizzazione del progetto coloniale del Mapa cor-de-rosa (simulazione cartografica delle pretese di sovranità del Portogallo sui territori situati tra Angola e Mozambico), smentendo così il mito di un esploratore guidato esclusivamente da scopi scientifici e di conoscenza. Attraverso un approccio storico e dialettico si è cercato di dimostrare come il dato scientifico non sia la causa determinante di queste pubblicazioni, alle quali i critici letterari hanno sempre mostrato poco interesse proprio a causa della loro presunta “scientificità”, definendole al più come paraletteratura. L’analisi di questi testi, nella comparazione con i diversi generi letterari dai quali attingono gli esploratori, oltre a testimoniare il perdurare di coordinate mentali “positivistiche” che inducono a una rinnovata assunzione dell’Altro e dell’Altrove come involuti antecedenti logico-storici del Sé occidentale, rivela al contrario la presenza di un alto tasso di letterarietà che li rende, anche per il loro valore perlocutivo, del tutto simili a romanzi d’avventura piuttosto che a trattati scientifico-accademici. [a cura dell'Autore]
The Praxis of Writing Strategies for Scholarly Publications in Higher Education: Indonesian EFL Lecturers’ Voices
Creators: name: Sudirman, Anselmus
name: Gemilang, Adria Vitalya
name: Kristanto, Thadius Marhendra Adi
Publisher: name: Academia
Year: 2023
Subjects: Writing for publications, writing knowledge, scientific publications, publication productivity

description: Writing strategies for scholarly publications in higher education have been essential to improving the quality of scientific articles. This research aims (1) to describe writing strategies that Indonesian EFL lecturers use when writing for scholarly publications and (2) to find out the implications of the writing strategies for their scholarly publications in higher education. This qualitative research primarily involved Indonesian EFL lecturers (N = 20) in three higher education institutions. The research instrument used to obtain the data was open and in-depth interviews. The data were broken down into broader ideas of distinct topics or themes using a qualitative research framework, which were then analyzed by sorting and evaluating code categories of narratives during the analytical processes. The finding showed that EFL lecturers play critical roles in developing writing strategies, devising scholarly publication ideas, submitting and publishing new articles, and inspiring the world through academic publications. Furthermore, selecting appropriate writing styles implies that developing self-inquiry skills, writing drafts, editing, and submitting scientific articles require the development of reflection abilities, all of which have been under-explored in recent studies of the same field in higher education EFL contexts.
description: Academia, Αρ. 33 (2023)
title: Imaging patients on extracorporeal life support - ECLS
Creators: name: Capilli, Fabio
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Cardiovascular system
subject: Cardiac
subject: CT
subject: CT-Angiography
subject: Surgery
subject: Cardiac Assist Devices

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To know the mainclinical indications , as well as the different possible configurations of extracorporeal life support systems ( ECLS ). To recognise the correct placement of the cannulas . To get an overview of themost commonly associated...
Aggregation of α-Synuclein in S. cerevisiae is Associated with Defects in Endosomal Trafficking and Phospholipid Biosynthesis
Creators: name: Lee, Virginia M.-Y.
name: Soper, James H.
name: Kehm, Victoria
name: Burd, Christopher G.
name: Bankaitis, Vytas A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Parkinson’s disease is the most common neuro-degenerative movement disorder. α-Synuclein is a small synaptic protein that has been linked to familial Parkinson’s disease (PD) and is also the primary component of Lewy bodies, the hallmark neuropathology found in the brain of sporadic and familial PD patients. The function of α-synuclein is currently unknown, although it has been implicated in the regulation of synaptic vesicle localization or fusion. Recently, overexpression of α-synuclein was shown to cause cytoplasmic vesicle accumulation in a yeast model of α-synuclein toxicity, but the exact role α-synuclein played in mediating this vesicle aggregation is unclear. Here, we show that α-synuclein induces aggregation of many yeast Rab GTPase proteins, that α-synuclein aggregation is enhanced in yeast mutants that produce high levels of acidic phospholipids, and that α-synuclein colocalizes with yeast membranes that are enriched for phosphatidic acid. Significantly, we demonstrate that α-synuclein expression induces vulnerability to perturbations of Ypt6 and other proteins involved in retrograde endosome–Golgi transport, linking a specific trafficking defect to α-synuclein phospholipid binding. These data suggest new pathogenic mechanisms for α-synuclein neurotoxicity.
Regularization of zero-range effective interactions in finite nuclei
Creators: name: Brenna, Marco
name: Colò, Gianluca
name: Roca-Maza, Xavier
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The problem of the divergences which arise in beyond mean-field calculations, when a zero-range effective interaction is employed, has not been much considered so far. Some of us have proposed, quite recently, a scheme to regularize a zero-range Skyrme-type force when it is employed to calculate the total energy, at second-order perturbation theory level, in uniform matter. Although this scheme looked promising, the extension for finite nuclei is not straightforward. We introduce such procedure in the current paper, by proposing a regularization procedure that is similar, in spirit, to the one employed to extract the so-called V_{\rm low-k} from the bare force. Although this has been suggested already by B.G. Carlsson and collaborators, the novelty of our work consists in setting on equal footing uniform matter and finite nuclei; in particular, we show how the interactions that have been regularized in uniform matter behave when they are used in a finite nucleus with the corresponding cutoff. We also address the problem of the validity of the perturbative approach in finite nuclei for the total energy.
description: Accepted in Phys. Rev. C (https://journals.aps.org/prc/accepted/4207aPfaIc313f02133c78b61b9c320e0a4e115d5)
Gender Differences in Leg Stiffness and Stiffness Recruitment Strategy During Two-Legged Hopping
Creators: name: Carcia, Christopher R.
name: Padua, Darin A.
name: Arnold, Brent L.
name: Granata, Kevin P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: The authors compared leg stiffness (KVERT), muscle activation, and joint movement patterns between 11 men and 10 women during hopping. Physically active and healthy men and women performed continuous 2-legged hopping at their preferred rate and at 3.0 Hz. Compared with men, women demonstrated decreased KVERT; however, after the authors normalized for body mass, gender differences in KVERT were eliminated. In comparison with men, women also demonstrated increased quadriceps and soleus activity, as well as greater quadriceps-to-hamstrings coactivation ratios. There were no significant gender differences for joint movement patterns (p > .05). The relationship between the observed gender differences in muscle recruitment and the increased risk of anterior cruciate ligament injury in women requires further study.