cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Exploring the effect of surfactants on the interactions of manganese dioxide nanoparticles with biomolecules
Creators: name: Khan, Shagufta
name: Balyan, Prairna
name: Ali, Ahmad
name: Sharma, Shweta
name: Sachar, Shilpee
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Interactions of manganese dioxide nanoparticles (MnO2 NPs) with vital biomolecules namely deoxyribonucleic acid (DNA) and serum albumin (BSA) have been studied in association with different surfactants by using fluorescence (steady state, synchronous and 3D), UV-visible, resonance light scattering (RLS), dynamic light scattering (DLS), and sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). The esterase activity of serum albumin was tested in associations with MnO2 NPs and surfactants. The antioxidant potential of prepared NPs was also evaluated (DPPH method). Gel electrophoresis was carried out to analyze the effect of MnO2 NPs and surfactants on DNA. Presence of CTAB, Tween 20, DTAB and Tween 80 enhanced nanoparticle-protein binding. Tween 20 based nanoparticle systems showed long-term stability and biocompatibility. The quenching of BSA fluorescence emission in presence of MnO2 NPs alone and along with Tween 20 revealed stronger association of nanoparticles with proteins. Enhancement in the esterase activity (BSA) was observed in the presence of Tween 20. Furthermore, radical scavenging activity showed highest antioxidant potential in presence of Tween 20. The enthalpy and entropy assessment for protein-NPs association showed the predominance of Vander Waals interactions and hydrogen bonding. The synchronous fluorescence analysis highlighted the involvement of tryptophan (Trp) in the MnO2 NPs-protein interactions. The study evaluates the influence of surfactant on the associations of MnO2 NPs with the essential biomolecules. The findings can be crucially utilized in designing biocompatible MnO2 formulations for long term applications. Influence of conventional surfactants on MnO2 NPs- protein interactions. Tween 20 causes no harm to DNA and protein structures and delivers long-term biocompatibility. Static mode of quenching is observed for MnO2 NPs/Tween 20-protein systems. The thermodynamic analysis signifies the dominance of Vander Waals interactions and hydrogen bonding amongst MnO2 NPs/Tween 20 and BSA systems. The findings will aid in designing stable and biocompatible MnO2 NPs for future therapeutic application.
Capusa cuculloides R. Felder
Creators: name: Young, Catherine J.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Geometridae
Capusa
Capusa cuculloides

description: Capusa cuculloides R. Felder (Figs 454–463)
Oviposition
3♀ Code no.: G83, G283, G473
Period of oviposition: 1 Jun.–5 Jul.
Batch size: 42.0 ± 6.6 range: 20–50 (n = 5)
Realised fecundity (range): 60–90
 Note: Although McFarland (1988) reported a realised fecundity in one female of 500 eggs and also batch sizes of 10–300.
Incubation time (days): 18–24
 Batch configuration and attachment: Attached to substrate by posterior pole, laid upright in large groups consisting of neat rows with every adjacent row off­set by one egg (Figs 454–455).
 Colour: Olive green, shiny, with white mesh­like reticulation, becoming grey after 2 days, brown after 10 days (Figs 454–455).
 Size (mm): (n=19) L =0.86 ± 0.01, W=0.76 ± 0.01, T=0.66 ± 0.01
Width/length: 0.90
No. of females: 3
 Aeropylar opening size (m) (n=5): L=2.1 ± 0.14, W=1.5 ± 0.11
Relative aeropylar opening size: 2.9
 Micropyles: Distinct (Figs 454–457)
No. of openings: 4
No. of cells in rosette: 7
No. of rows of cells in micropylar area: 4
 Shape: Broad, bluntly ovoid, anterior pole markedly truncated, much wider than posterior, polar profile sub­circular, dorso­ventrally flattened (Figs 454–457).
 Characteristics: Egg marked all over by hexagonal cells with concave floors (Figs 454–456, 458–60), but cells only faintly discernible in posterior half of egg (Figs 458, 459 & 461). Moderately wide, elevated cell walls reticulated on anterior half of egg (Figs 454, 458–460). Aeropyles moderately elevated, domed, openings moderately large (Figs 457 & 460), present on anterior pole and in area adjacent to anterior pole (Fig. 457). Chorion deeply ridged, folded on anterior half of egg (Fig. 462), smoother on posterior half (Fig. 463). Micropylar area slightly recessed (Fig. 457).
description: Published as part of Young, Catherine J., 2006, Descriptions of the eggs of some southern Australian Geometridae (Lepidoptera), pp. 1-294 in Zootaxa 1287 on pages 1-294
Polyethylene glycol molecular crowders enhance the catalytic ability of bimolecular bacterial RNase P ribozymes
Creators: name: Md. Sohanur Rahman
name: Mst. Ara Gulshan
name: Matsumura, Shigeyoshi
name: Ikawa, Yoshiya
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 60506 Virology

description: The modular structure of bacterial ribonuclease P (RNase P) ribozymes, which recognize tertiary structures of precursor tRNAs (pre-tRNAs) to cleave their 5′ leader sequence, can be dissected physically into the two structured domain RNAs (S-domain and C-domain). Separately prepared S-domain RNA and C-domain RNA assemble to form bimolecular forms of RNase P ribozymes. We analyzed the effects of polyethylene glycols (PEGs) on pre-tRNA cleavage catalyzed by bimolecular RNase P ribozymes to examine the effects of molecular crowding on the reaction. PEG molecular crowders significantly enhanced the activities of bimolecular RNase P ribozymes, some of which were hardly active without PEGs.
Fine structure of low-energy H+ in the nightside auroral region
Creators: name: Liu, Chao
name: Perez, J.D.
name: Moore, T.E.
name: Chappell, C.R.
name: Slavin, J.A.
Publisher: name: American Geophysical Union
Year: 1994

description: Low-energy H+ data with 6-s resolution from the retarding ion mass spectrometer instrument on DE 1 have been analyzed to reveal the fine structure at middle altitudes of the nightside auroral region. A new method for deconvolving the energy-integrated count rate in the spin plane of the satellite has been used to derive the two-dimensional phase space density. A detailed analysis reveals an alternating conic-beam-conic pattern with the observed conics correlated with large earthward currents in the auroral region. The strong downward current (>1 µA/m2 (equivalent value at ionosphere)) provides a free energy source for the perpendicular ion heating, that generates the ion conics with energies from several eV to tens of eV. The bowl shape distribution of the low-energy H+ is caused by the extended perpendicular heating. The strong correlation between conics and large downward currents suggests that the current-driven electrostatic ion cyclotron wave is an appropriate candidate for the transverse heating mechanism.
A metadata portal for complex research data in Germany: An application of DDI
Creators: name: Schiller, David
name: Mueller, Dana
name: Barkow, Ingo
Publisher: name: Zenodo
Year: 2014

description: The research data centre of the Federal Employment Agency in the Institute of Employment Research provides different types of data for the scientific community. There are register data, survey data and linked data between surveys and register data for example. Available metadata tools do not consider the variety of research data of the research data centre and the workflow of the data documentation within departments and the collaboration between departments. Therefore we have started an international development project in cooperation with TBA 21 Assessment Systeme GmbH (Germany), OPIT Consulting Kft. (Hungary) and Colectica (USA) in 2012 to handle and standardized the metadata for all kinds of data in one technical application. Beside the metadata portal there will be a web application for the data users. The focuses of the presentation is the appropriate subset of the DDI standard first and second the application of the metadata portal for users as well as the workflow within departments e.g. user administration and less the technical structure behind the metadata portal.
Detection of Close-In Extrasolar Giant Planets Using the Fourier-Kelvin Stellar Interferometer
Creators: name: Danchi, William C.
name: Deming, Drake
name: Kuchner, Marc J.
name: Seager, Sara
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We evaluate the direct detection of extrasolar giant planets with a two-aperture nulling infrared interferometer, working at angles $θ
description: Accepted for publication in ApJ Letters
Farm Capabilities and Performance in Swedish Agriculture
Creators: name: Nybom, Jozefine
name: Hunter, Erik
name: Micheels, Eric T.
name: Melin, Martin
name: Nybom, Jozefine
name: Hunter, Erik
name: Micheels, Eric T.
name: Melin, Martin
Publisher: name: Unknown
Year: 2019
Subjects: Agribusiness

description: Presentation ID 16491
On the Atomki nuclear anomaly after the MEG-II result
Creators: name: Barducci, Daniele
name: Germani, Davide
name: Nardecchia, Marco
name: Scacco, Stefano
name: Toni, Claudio
Publisher: name: arXiv
Year: 2025
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Recent experimental results from the Atomki collaboration have reported the observation of anomalous effects in Beryllium, Helium and Carbon nuclear transitions that could hint at physics beyond the Standard Model. However, the MEG-II experiment has recently found no significant anomalous signal in the Beryllium transition ${^8}\text{Be}^\star\to{^8}\text{Be}+e^+e^-$. In view of this result, we critically re-examine the possible theoretical interpretations of the anomalies observed by the Atomki experiment in terms of a new boson $X$ with mass around $17\;$MeV. The present work aims to study the phenomenology of a spin-2 state and revisit the possibility of a pure CP-even scalar, which was initially dismissed due to its inability to explain the Beryllium anomalous signal. Our analysis shows that a spin-2 state is highly disfavoured by the SINDRUM constraint while a scalar boson could explain the Helium and Carbon anomalies while being compatible with other experimental constraints.
description: 29 pages, matched to the published version
Pure-bred Nellore Prices in Brazil: Morphological, Genetic, Physical, and Market Factors in Auctions
Creators: name: Calil, Yuri Clements Daglia
name: Ribera, Luis A.
name: Anderson, David P.
name: Koury Filho, William
name: Calil, Yuri Clements Daglia
name: Ribera, Luis A.
name: Anderson, David P.
name: Koury Filho, William
Publisher: name: Unknown
Year: 2019
Subjects: Agribusiness

description: Presentation ID 16500
de Haan et al. Revised Supplement (short title: Transcriptional determinants of LSEC specialization)
Creators: name: Luttun, Aernout
name: Oie, Cristina
name: Benkheil, Mohammed
name: Dheedene, Wouter
name: Vinckier, Stefan
name: Coppiello, Giulia
name: Aranguren, Xabier L.
name: Beerens, Manu
name: Jaekers, Joris
name: Topal, Baki
name: Verfaillie, Catherine
name: Smedsrød, Bård
name: Haan, Willeke De
Publisher: name: figshare
Year: 2020
Subjects: subject: 110307 Gastroenterology and Hepatology
subject: FOS: Clinical medicine

description: Supplementary info (Figures, n=5; Tables, n=5, references, n=155); clean version without highlighted revisions
Design, synthesis, biological evaluations and in silico studies of N-substituted 2,4-thiazolidinedione derivatives as potential a-glucosidase inhibitors
Creators: name: Dahiya, Lalita
name: Kumar, Rajiv
name: Baidya, Anurag T. K.
name: Kumar, Sunil
name: Kumar, Rajnish
name: Pawar, Sandip V.
name: Yadav, Ashok Kumar
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Space Science
Medicine
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: Diabetes mellitus is considered as one of the principal global health urgencies of the twenty first century. In the present investigation, novel N-substituted 2,4-thiazolidinedione derivatives were designed, synthesized, and characterized by spectral techniques. All the newly synthesized N-substituted 2,4-thiazolidinedione derivatives were tested for in vitro α-glucosidase inhibitory activities and compounds A-12 and A-14 were found to be the most potent which were further subjected to in-vivo disaccharide loading test. The most potent compound was also found to be non-toxic in cytotoxicity studies. Further, docking studies were carried out to investigate the binding mode and key interactions with amino acid residues of α-glucosidase. Molecular dynamic simulations studies for the compounds acarbose, A2, A12, and A14 were done with α-glucosidase protein. Further, ΔG was calculated for acarbose, A2, A12, and A14. In silico studies and absorption, distribution, metabolism, excretion (ADME) prediction studies were also executed to establish the ‘druggable’ pharmacokinetic profiles. Here, we have developed novel N-substituted TZD analogues with different alkyl groups as α-glucosidase inhibitors.
Adjointable maps between linear orthosets
Creators: name: Paseka, Jan
name: Vetterlein, Thomas
Publisher: name: arXiv
Year: 2025
Subjects: subject: Rings and Algebras (math.RA)
subject: Logic (math.LO)
subject: FOS: Mathematics
subject: 46C05, 06C15, 15A04, 51A10, 51F20

description: Given an (anisotropic) Hermitian space $H$, the collection $P(H)$ of at most one-dimensional subspaces of $H$, equipped with the orthogonal relation $\perp$ and the zero linear subspace $\{0\}$, is a linear orthoset and up to orthoisomorphism any linear orthoset of rank $\geq 4$ arises in this way. We investigate in this paper the correspondence of structure-preserving maps between Hermitian spaces on the one hand and between the associated linear orthosets on the other hand. Our particular focus is on adjointable maps.
 We show that, under a mild assumption, adjointable maps between linear orthosets are induced by quasilinear maps between Hermitian spaces and if the latter are linear, they are adjointable as well. Specialised versions of this correlation lead to Wigner-type theorems; we see, for instance, that orthoisomorphisms between the orthosets associated with at least $3$-dimensional Hermitian spaces are induced by quasiunitary maps.
 In addition, we point out that orthomodular spaces of dimension $\geq 4$ can be characterised as irreducible Fréchet orthosets such that the inclusion map of any subspace is adjointable. Together with a transitivity condition, we may in this way describe the infinite-dimensional classical Hilbert spaces.
Emissions of photons near the horizons of Kerr-Sen black holes
Creators: name: Zhang, Ming
name: Jiang, Jie
Publisher: name: arXiv
Year: 2020
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the escape probabilities of the photons near the horizon of the Kerr-Sen black hole. We find that the escape probabilities of the photons are nonzero in the event horizon limit of the extreme Kerr-Sen black hole if the light sources are near the equator. We show that the escape probability of a photon increases with the radial position of the light source. It is also uncovered that the escape probability decreases if the light source with constant radius moves from the equatorial plane to the pole. Besides, we discover that the escape probability of a photon in the Carter frame is always greater than the one in the locally non-rotating frame, except on the pole, where they are equal.
description: 12 pages, 15 captioned figures, Sec. IV added
Road Infrastructure and Poverty Alleviation: Evidence from Rural China
Creators: name: Zhu, Lifen
name: Jin, Songqing
name: Huang, Jikun
name: Tian, Yongzhong
name: Zhu, Lifen
name: Jin, Songqing
name: Huang, Jikun
name: Tian, Yongzhong
Publisher: name: Unknown
Year: 2019
Subjects: Agribusiness

description: Presentation ID 16570
Induced Universal Properties and Deconfinement
Creators: name: Mocsy, Agnes
name: Sannino, Francesco
name: Tuominen, Kimmo
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We propose a general strategy to determine universal properties induced by a nearby phase transition on a non-order parameter field. A general renormalizable Lagrangian is used, which contains the order parameter and a non-order parameter field, and respects all the symmetries present. We investigate the case in which the order parameter field depends only on space coordinates and the case in which this field is also time dependent. We find that the spatial correlators of the non-order parameter field, in both cases, are infrared dominated and can be used to determine properties of the phase transition. We predict a universal behavior for the screening mass of a generic singlet field, and show how to extract relevant information from such a quantity. We also demonstrate that the pole mass of the non-order parameter field is not infrared sensitive. Our results can be applied to any continuous phase transition. As an example we consider the deconfining transition in pure Yang-Mills theory, and show that our findings are supported by lattice data. Our analysis suggests that monitoring the spatial correlators of different hadron species, more specifically the derivatives of these, provides an efficient and sufficient way to experimentally uncover the deconfining phase transition and its features.
description: Added computational details and improved the text. The results are unchanged
Higher-order bias corrections for kernel type density estimators on the unit or semi-infinite interval
Creators: name: Gaku Igarashi
name: Kakizawa, Yoshihide
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: For the data of size n from the unit or semi-infinite interval, several asymmetric kernel density estimators, having the mean integrated squared errors of order O(n−4/5) or O(n−8/9), are available in the literature. We develop more higher-order bias-corrected estimators, achieving the order O(n−4p/(4p+1)), where p≥2 is a given integer. We illustrate the finite sample performance of the estimators through the simulations.
Capusa senilis Walker 1857
Creators: name: Young, Catherine J.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Geometridae
Capusa
Capusa senilis

description: Capusa senilis Walker (Figs 464–474)
(type species)
Oviposition
3♀ Code no.: G286, G289, G300
Period of oviposition: 30 Sept.–9 Nov.
Batch size: 51.5 ± 10.1 (n = 13)
Realised fecundity: 150–280
Incubation time (days): 10.3 ± 0.5
 Batch configuration and attachment: Attached to substrate by posterior pole, laid upright in large groups in neat rows with every row off­set (Figs 464–466).
 Colour: Olive green with white mesh­like reticulation, shiny, becoming grey on maturity (Figs 464 & 466).
 Size (mm): (n=19) L =0.78 ± 0.01, W=0.57 ± 0.01, T=0.57 ± 0.01
Width/length: 0.73
No. of females: 3
 Aeropylar opening size (m) (n=6): L=2.4 ± 0.08, W=2.3 ± 0.08
Relative aeropylar opening size: 2.9
 Micropyles: Distinct (Figs 464–468)
No. of openings: 4
No. of cells in rosette: 6
No. of rows of cells in micropylar area: 4
 Shape: Moderately broad, bluntly ovoid, anterior pole markedly truncated, much wider than posterior, polar profile sub­circular, dorso­ventrally flattened (Figs 464–467, 469–470).
 Characteristics: Egg marked all over by hexagonal cells with concave floors (Figs 465, 467, 469–471), cells only faintly discernible on posterior half of egg (Figs 465, 469, 470 & 472). Moderately wide, elevated cell walls only reticulated on anterior half of egg. Reticulated cell walls double­ridged (Figs 473 & 474). Aeropyles moderately elevated, domed, openings moderately large present in area adjacent to anterior pole (Fig. 474). Chorion deeply ridged, folded on anterior half of egg (Fig. 473 & 474), smoother on posterior half (Fig. 472).
description: Published as part of Young, Catherine J., 2006, Descriptions of the eggs of some southern Australian Geometridae (Lepidoptera), pp. 1-294 in Zootaxa 1287 on pages 1-294
Managing and curating undergraduate-generated qualitative data
Creators: name: Rogers, Peter
Publisher: name: Zenodo
Year: 2014

description: This paper reports on a project at Colgate University. The Department of Sociology and Anthropology (SOAN), working with the library and Information Technology Services, is creating an archive for students' qualitative data. SOAN has clear pedagogical goals for this project. One, allow students doing local research to build upon the work of previous students who have done similar projects and to avoid duplication of effort. Two, make greater use of student data. Often the student who does the data collection spends most of their time on that and has little time left over for data analysis. Three, give students a fuller data collection, analysis, and management experience. I will report upon my experiences as the data librarian on this project and the lessons that have been learned. At the moment, we are using a Dataverse on the Harvard Dataverse Network. This has been easy to create, but it means that we have to conform to certain standards built into this network. There are also challenges associated with the focus on qualitative data which can include interview transcripts, scanned magazine ads, and text from newspapers and other documentary sources.
Intermediate efficiency of some weighted goodness-of-fit statistics
Creators: name: Ćmiel, Bogdan
name: Inglot, Tadeusz
name: Ledwina, Teresa
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: This paper introduces and investigates powerful omnibus test for uniformity and compares it with some classical and recent solutions. All statistics under consideration are weighted functionals of the classical empirical process. The goal is to provide a quantitative comparison of tests under consideration and to study real possibilities of using them to detect departures from the hypothesised distribution that occur in the tails. The newly introduced concept of pathwise variant of intermediate efficiency serves to achieve the goal. This contribution covers the case when under the alternative a moderately large portion of probability mass is allocated towards the tails. It is demonstrated that the approach allows for tractable, analytic comparison between the given test and the benchmark, and for reliable quantitative evaluation of weighted statistics. Finite sample results illustrate the proposed approach and confirm the theoretical findings.
Optimal cost-sharing rules for efficient water-resource development
Creators: name: Marshall, Harold E.
name: Marshall, Harold E.
Publisher: name: Unknown
Year: 1969
Subjects: Resource /Energy Economics and Policy

description: Inconsistencies are inherent in the cost-sharing rules applied to water-resource development by different Federal agencies for different project purposes. These inconsistencies have been criticized by both Federal and local interests in vague terms of "equity" and "efficiency," but no one has provided a model--needed by policy makers--that explains the relationships between alternative cost-sharing rules and efficiency. The model presented herein is designed to (l) measure the loss of economic efficiency that can result from different cost-sharing rules and (2) provide optimal cost-sharing rules that induce efficient water-resource development. The optimal rules call for an "association" of benefits and costs and "equal" cost-sharing for all ways of providing a single project purpose.
Molecular dynamics simulations suggest novel allosteric modes in the Hsp70 chaperone protein
Creators: name: Mahto, Farindra Kumar
name: Bhattacharya, Akash
name: Bhattacharya, Swati
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Physical Sciences not elsewhere classified
Medicine
Cell Biology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Computational Biology

description: The Hsp70 chaperone protein system is an essential component of the protein folding and homeostasis machinery in E.Coli. Hsp70 is a three domain, 70 kDa protein which functions as an allosteric system cycling between an ADP-bound state where the three domains are loosely coupled via a flexible interdomain linker and an ATP-bound state where they are tightly coupled into a single entity. The structure-function model of this protein proposes an allosteric connection between the 45 kDa Nucleotide Binding Domain (NBD) and the 25 kDa Substrate Binding Domain (SBD) and Lid Domain which operates through the inter NBD-SBD linker. X-Ray crystallography and NMR spectroscopy have provided structures of the end states of the functional cycle of this protein, bound to ADP and ATP. We have used MD simulations to study the transitions between these end states and allosteric communication in this system. Our results largely validate the experimentally derived allosteric model of function, but shed additional light on the flow of allosteric information in the SBD + Lid. Specifically, we find that the Lid domain has a double-hinged structure with the potential for greater conformational flexibility than was hitherto expected.
Calculation of The Critical Temperature for Anisotropic Two-Layer Ising Model Using The Transfer Matrix Method
Creators: name: Ghaemi, M.
name: Ghannadi, M.
name: Mirza, B.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: A new finite-size scaling approach based on the transfer matrix method is developed to calculate the critical temperature of anisotropic two-layer Ising ferromagnet, on strips of r wide sites of square lattices. The reduced internal energy per site has been accurately calculated for the ferromagnetic case, with the nearest neighbor couplings Kx, Ky (where Kx and Ky are the nearest neighbor interactions within each layer in the x and y directions, respectively) and with inter-layer coupling Kz, using different size-limited lattices. The calculated energies for different lattice sizes intersect at various points when plotted versus the reduced temperature. It is found that the location of the intersection point versus the lattice size can be fitted on a power series in terms of the lattice sizes. The power series is used to obtain the critical temperature of the unlimited two-layer lattice. The results obtained, are in good agreement with the accurate values reported by others.
description: 12 pages, 1 table, 2 figures
Global Organization of Three-Dimensional, Volume-Preserving Flows: Constraints, Degenerate Points, and Lagrangian Structure
Creators: name: Ravu, Bharath
name: Metcalfe, Guy
name: Rudman, Murray
name: Lester, Daniel R.
name: Khakhar, Devang V.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Global organization of 3-dimensional (3D) Lagrangian chaotic transport is difficult to infer without extensive computation. For 3D time-periodic flows with one invariant we show how constraints on deformation that arise from volume-preservation and periodic lines result in resonant degenerate points that periodically have zero net deformation. These points organize all Lagrangian transport in such flows through coordination of lower-order and higher-order periodic lines and prefigure unique transport structures that arise after perturbation and breaking of the invariant. Degenerate points of periodic lines and the extended 3D structures associated with them are easily identified through the trace of the deformation tensor calculated along periodic lines. These results reveal the importance of degenerate points in understanding transport in one-invariant fluid flows.
Measurements of the Higgs boson inclusive and differential fiducial cross sections in the 4$\ell$ decay channel at $\sqrt{s}$ = 13 TeV
Creators: name: ATLAS Collaboration
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Inclusive and differential fiducial cross sections of the Higgs boson are measured in the $H \to ZZ^{*} \to 4\ell$ ($\ell = e,μ$) decay channel. The results are based on proton$-$proton collision data produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector from 2015 to 2018, equivalent to an integrated luminosity of 139 fb$^{-1}$. The inclusive fiducial cross section for the $H \to ZZ^{*} \to 4\ell$ process is measured to be $σ_\mathrm{fid} = 3.28 \pm 0.32$ fb, in agreement with the Standard Model prediction of $σ_\mathrm{fid, SM} = 3.41 \pm 0.18 $ fb. Differential fiducial cross sections are measured for a variety of observables which are sensitive to the production and decay of the Higgs boson. All measurements are in agreement with the Standard Model predictions. The results are used to constrain anomalous Higgs boson interactions with Standard Model particles.
description: 92 pages in total, author list starting page 75, 43 figures, 9 tables, published to EPJC. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HIGG-2018-29
Palleopa innotata Walker 1866
Creators: name: Young, Catherine J.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Geometridae
Palleopa
Palleopa innotata

description: Palleopa innotata Walker (Figs 475–481)
(type species)
Oviposition
2♀ Code no.: G54, G146.
Period of oviposition: 19 Jan.–18 Feb.
Batch size: 55.0 ± 15.0 range: 35–100; (n = 5)
Realised fecundity: 35–200.
Incubation time (days): 17–22
 Batch configuration and attachment: Laid upright in neat rows, large groups (Fig. 475).
 Colour: Pale olive green, shiny, anterior pole milky white, becoming dark olive green (Fig. 475).
 Size (mm): (n=15) L=1.03 ± 0.13, W=0.82 ± 0.17, T=0.74 ± 0.06
Width/length: 0.80
No. of females: 2
 Aeropylar opening size (m) (n=5): L= 2.81 ± 0.11, W= 2.02 ± 0.12
Relative aeropylar opening size: 3.5
 Micropyles: Distinct (Figs 475, 477 & 478)
No. of openings: 5
No. of cells in rosette: 13
No. of rows of cells in micropylar area: 4
 Shape: Upright, broad, sub­quadrate; anterior pole slightly wider than posterior pole, truncated; polar profile circular; flattened dorso­ventrally (Figs 475 & 479).
 Characteristics: Egg marked on all surfaces by rounded hexagonal cells (Figs 475–477, 479 & 480) scarcely discernible on posterior 2/3 of egg (Figs 476 & 479). Cells on anterior 1/3 of egg with elevated walls (Fig. 480); elevated aeropyles at junctions of cell walls, openings moderately large (Fig. 480). Chorion generally smooth, but appearing sparsely granular on posterior 2/3 of egg (Fig. 481), wrinkled on anterior 1/3 (Fig. 480).
description: Published as part of Young, Catherine J., 2006, Descriptions of the eggs of some southern Australian Geometridae (Lepidoptera), pp. 1-294 in Zootaxa 1287 on pages 1-294
Canada’s Food Guide and its role in home economics education
Creators: name: Meier, Katherine
Publisher: name: The University of British Columbia
Year: 2023

description: In this paper, I review how Canada’s Food Guide was developed and how it can be used in Home Economics classrooms. With the release of the newest version of the CFG, there has been a shift in understanding food as more than just the nutrients it provides. The new guide encourages enjoying food, eating mindfully, and preparing food at home as strategies to develop positive relationships with food and healthy eating habits. I describe the origins of dietary guidelines, specifically food guides, and explore the changes over time. I describe how BC's past and current home economics curriculum has approached using CFG in teaching nutrition and food literacy. I created a teaching resource to support the use of the new food guide in home economics classrooms. The guide offers suggestions that encourage critically thinking about the use, development, and role of food-based dietary guides.
Ray helicity: a geometric invariant for multi-dimensional resonant wave conversion
Creators: name: Tracy, E. R.
name: Kaufman, A. N.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Classical Physics (physics.class-ph)
subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: For a multicomponent wave field propagating into a multidimensional conversion region, the rays are shown to be helical, in general. For a ray-based quantity to have a fundamental physical meaning it must be invariant under two groups of transformations: congruence transformations (which shuffle components of the multi-component wave field) and canonical transformations (which act on the ray phase space). It is shown that for conversion between two waves there is a new invariant not previously discussed: the intrinsic helicity of the ray.
Two-step combined nonparametric likelihood estimation of misspecified semiparametric models
Creators: name: Bravo, Francesco
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: This paper proposes to estimate possibly misspecified semiparametric estimating equations models using a two-step combined nonparametric likelihood method. The method uses in the first step the plug in principle and replaces the infinite dimensional parameter with a consistent estimator. In the second step an estimator for the finite dimensional parameter is obtained by combining exponential tilting with a another member of the empirical Cressie-Read discrepancy. The resulting class of semiparametric estimators are robust to misspecification and have the same asymptotic variance as that of the efficient semiparametric generalised method of moment estimator under correct specification. It is also shown that the asymptotic distributions of the proposed estimators can be consistently estimated by a multiplier bootstrap procedure. The results of the paper are illustrated with a quadratic inference function model and an instrumental variable partially linear additive model. Monte Carlo evidence suggests that the proposed estimators have competitive finite sample properties.
Critical Load Restoration using Distributed Energy Resources for Resilient Power Distribution System
Creators: name: Poudel, Shiva
name: Dubey, Anamika
Publisher: name: arXiv
Year: 2019
Subjects: subject: Systems and Control (eess.SY)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Extreme weather events have a significant impact on the aging and outdated power distribution infrastructures. These high-impact low-probability (HILP) events often result in extended outages and loss of critical services, thus, severely affecting customers' safety. This calls for the need to ensure resilience in distribution networks by quickly restoring the critical services during a disaster. This paper presents an advanced feeder restoration method to restore critical loads using distributed energy resources (DERs). A resilient restoration approach is proposed that jointly maximizes the amount of restored critical loads and optimizes the restoration times by optimally allocating grid's available DER resources. The restoration problem is modeled as a mixed-integer linear program with the objective of maximizing the resilience to post-restoration failures while simultaneously satisfying grid's critical connectivity and operational constraints and ensuring a radial operation for a given open-loop feeder configuration. Simulations are performed to demonstrate the effectiveness of the proposed approach using IEEE 123-node feeder with 5 DERs supplying 11 critical loads and IEEE 906-bus feeder with 3 DERs supplying 17 critical loads. The impacts of DER availability and fuel reserve on restored networks are assessed and it is shown that the proposed approach is successfully able to restore a maximum number of critical loads using available DERs.
description: 11 Pages, 3 Figures, Journal
Creating a large-cale collection of genuinely teacher-ready teaching datasets
Creators: name: Bronia Flett
name: Brindle, Patrick
Publisher: name: Zenodo
Year: 2014

description: SAGE Publications is in the process of starting to put together a large collection of many 100s of teaching datasets that can enable faculty, new researchers and students to teach or self-teach across a wide range of many 100s of analytic techniques. The collection will cover quantitative and qualitative data, but comes with many developmental challenges in terms of working out how to best develop different datasets to showcase markedly different methodological techniques and to do so in way that is easy to understand, easy to use and, perhaps, even fun for the user. This paper will summarise the challenges that the editorial team face in pulling together what will be an unprecedentedly large collection of teaching datasets and will canvas audience feedback on what might be seen as must-have or best practice from a librarian and library-user perspective. This aims to be an open-minded session and an opportunity for delegates to work closely with a publisher on thinking through some difficult yet important issues at the very start of a new project.
Fine-tuning the accretion disk clock in Hercules X-1
Creators: name: Still, M.
name: Boyd, P.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: RXTE ASM count rates from the X-ray pulsar Her X-1 began falling consistently during the late months of 2003. The source is undergoing another state transition similar to the anomalous low state of 1999. This new event has triggered observations from both space- and ground-based observatories. In order to aid data interpretation and telescope scheduling, and to facilitate the phase-connection of cycles before and after the state transition, we have re-calculated the precession ephemeris using cycles over the last 3.5 years. We report that the source has displayed a different precession period since the last anomalous event. Additional archival data from CGRO suggests that each low state is accompanied by a change in precession period and that the subsequent period is correlated with accretion flux. Consequently our analysis reveals long-term accretion disk behaviour which is predicted by theoretical models of radiation-driven warping.
description: 9 pages, 4 figures, ApJL in press
Didymoctenia exsuperata Walker 1860
Creators: name: Young, Catherine J.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Geometridae
Didymoctenia
Didymoctenia exsuperata

description: Didymoctenia exsuperata Walker (Figs 488–492)
(type species)
Oviposition
2♀ code nos.: G193, G202
Oviposition period: 19–28 Apr.
Batch range: 10–50; (n = 2)
Realised fecundity: 10–50
Incubation time (days): 28
 Batch configuration and attachment: Loosely attached, singly.
 Colour: Bluish­green, greyish brown on maturity.
 Size (mm): (n=5) L=0.73 ± 0.01, W=0.49 ± 0.01, T=0.38 ± 0.01
Width/length: 0.67
No. of females: 1
 Aeropylar opening size (m) (n=1): L=2.72, W=1.35
Relative aeropylar opening size: 3.5
 Micropyles: Distinct (Figs 488 & 489)
No. of openings: 6
No. of cells in rosette: 8
No. of rows of cells in micropylar area: 3
 Shape: Very narrow, elongated, bluntly ovoid; anterior pole truncated; flattened dorso­ventrally; elongated (Figs 488 & 490).
 Characteristics: Chorion soft. Egg distinctly marked on all surfaces by concave polygonal cells with broad, rounded, wavy walls arranged in longitudinal rows (Figs 488 & 490–492), cell walls in micropylar area narrow (Fig. 489). Aeropyles inconspicuous, openings moderately large slightly elevated, domed (Fig. 488); present on all surfaces apart from middle of top of egg (Figs 490 & 492). Rosette cells in micropylar area recessed (Fig. 489). Chorion blistered, appearing granulated, ridged on and near anterior pole (Fig. 492).
description: Published as part of Young, Catherine J., 2006, Descriptions of the eggs of some southern Australian Geometridae (Lepidoptera), pp. 1-294 in Zootaxa 1287 on pages 1-294
Rational design of thiazolidine-4-one-gallic acid hybrid derivatives as selective partial PPARγ modulators: an in-silico approach for type 2 diabetes treatment
Creators: name: Aryan
name: Babu, B.
name: Divakar, S.
name: Gowramma, B.
name: Jupudi, Srikanth
name: Chand, Jagdish
name: Kumar, Vishnu Malakar
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: Type 2 diabetes mellitus is a bipolar metabolic disorder characterized by abnormalities in insulin production from β-cells and insulin resistance. Thiazolidinediones are potent anti-diabetic agents that act through the modulation of the peroxisome proliferator-activated receptor γ (PPARγ), a nuclear receptor. However, their full agonistic activity leads to severe side effects by stabilizing Helix12 through strong hydrogen bonding with the TYR473 residue. Partial and selective PPARγ modulators (GW0072, GQ16, VSP-51, MRL-20, MBX-213, INT131) have demonstrated superior results compared to full agonists without causing adverse effects, as reported in existing data. To address this uncertainty and advance therapeutic options, we identified and designed a novel class of compounds (A1-A23) based on a hybrid structure combining phenolic and Thiazolidine-4-one’s moieties. Our rational drug design strategy incorporated structural-activity relationship principle, and validated the docking studies through calculated the root mean square deviation. Additionally, we conducted molecular docking, binding energy, molecular dynamics simulations, and post-molecular dynamics calculations to evaluate the dynamics behavior between the ligands and protein. The selected ligands demonstrated highly favorable docking scores and binding energies, comparable to the co-crystal (rosiglitazone) such as A12 (−13.9 kcal/mol and −86.2 kcal/mol), A1 (−11.1 kcal/mol and −79.5 kcal/mol), A13 (−11.3 kcal/mol and −91.4 kcal/mol), and the co-crystal itself (−9.8 kcal/mol and −76 kcal/mol), respectively. Finally, the MD revealed that, the selected ligands were equally contributed for stabilization of Helix12 and β-sheets. It was concluded, the designed ligands (A12, A1, and A13) exhibited weaker hydrogen-bond interactions with specific residue TYR473 which partially modulated the PPARγ protein.
Decaying Superheavy Dark Matter and Subgalactic Structure of the Universe
Creators: name: Chou, Chung-Hsien
name: Ng, Kin-Wang
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The collisionless cold dark matter (CCDM) model predicts overly dense cores in dark matter halos and overly abundant subhalos. We show that the idea that CDM are decaying superheavy particles which produce ultra-high energy cosmic rays with energies beyond the Greisen-Zatsepin-Kuzmin cutoff may simultaneously solve the problem of subgalactic structure formation in CCDM model. In particular, the Kuzmin-Rubakov's decaying superheavy CDM model may give an explanation to the smallness of the cosmological constant and a new thought to the CDM experimental search.
description: 5 pages, 1 figure. Add a new paragraph on the production of UHECR. References added. Final version which is to appear in Phys.Lett.B
De novo drug designing coupled with brute force screening and structure guided lead optimization gives highly specific inhibitor of METTL3: a potential cure for Acute Myeloid Leukaemia
Creators: name: Ganguly, Manisha
name: Gupta, Radhika
name: Roychowdhury, Amlan
name: Hazra, Ditipriya
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Biochemistry
Molecular Biology
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Hematology

description: Expression of METTL3, a SAM dependent methyltransferase, which deposits m6A on mRNA is linked to poor prognosis in Acute Myeloid Leukaemia and other type of cancers. Down regulation of this epitranscriptomic regulator has been found to inhibit cancer progression. Silencing the methyltransferase activity of METTL3 is a lucrative strategy to design anticancer drugs. In this study 3600 commercially available molecules were screened against METTL3 using brute force screening approach. However, none of these compounds take advantage of the unique Y-shaped binding cavity of the protein, raising the need for de novo drug designing strategies. As such, 125 branched, Y-shaped molecules were designed by “stitching” together the chemical fragments of the best inhibitors that interact strongly with the METTL3 binding pocket. This results in molecules that have the three-dimensional structure and functional groups which enable it to fit in the METTL3 cavity like fingers in a glove, having unprecedented selectivity and binding affinities. The designed compounds were further refined based on Lipinski’s rule, docking score and synthetic accessibility. The molecules faring well in these criteria were simulated for 100 ns to check the stability of the protein inhibitor complex followed by binding free energy calculation.