cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
GENERAZIONE DI IPSC COME MODELLO IN VITRO E SVILUPPO DI UN POSSIBILE APPROCCIO TERAPEUTICO PER LA MALATTIA DI CHARCHOT-MARIE-TOOTH DI TIPO 2A(CMT2A)
Creators: name: RIZZO, FEDERICA
Publisher: name: Universit� degli Studi di Milano
Year: 2015

description: Charcot-Marie-Tooth disease type 2A (CMT2A) is a sensory-motor polyneuropathy, characterized by the involvement of motor and sensitive neurons, resulting in progressive weakness, limb muscle atrophy and loss of sensitivity. Mitofusin2 (MFN2) gene has been identified as causative of the disease. The MFN2 protein, located in the outer mitochondrial membrane, is involved in the mitochondrial network. Defects in this network are features of several neurodegenerative diseases. A treatment for CMT2A is not currently available. The development of an effective therapy needs a better understanding of the molecular mechanisms of the disease, not only to identify new therapeutic targets, but also to define biomarkers of the disease phenotype.
The first aim of this study was the generation of an in vitro disease model, not currently available. The reprogramming of mature somatic cells into induced pluripotent stem cells (iPSCs) provides the derivation of disease-specific cell types, such as motor and sensitive neurons, affected in the disease. Based on this method, we successfully generated human iPSCs from a CMT2A patient and demonstrated their differentiation into motor neurons. We analyzed mitochondrial phenotypes (i.e mitochondrial localization, content and stability of mitochondrial DNA, and respiratory capacity) associated with the disease in CMT2A motor neurons as well as in fibroblasts. In particular, we observed an alteration in mitochondria localization, a reduction in the amount of mitochondrial DNA and a dysfunction of the mitochondrial respiratory chain, identifying specific hallmarks of the disease phenotype. These defects are more evident in neuronal cells compared to fibroblasts, in agreement with neuronal specificity of the disease.
In addition in vitro models, the analysis of these aspects has been conducted in the only currently available murine model of CMT2A (MitoCharc 1) to extend its characterization, searching for biomarkers of disease phenotype.
The second aim of this work was the development of a therapeutic approach for this disorder. We silenced endogenous MFN2 gene by short harpin RNA (shRNA) in CMT2A fibroblasts. At the same time, in order to restore correct MFN2 protein levels, we transfected a MFN2 c-DNA modified to be resistant to shRNA-mediated silencing. The results of this strategy were very promising in CMT2A fibroblasts, and preliminary data were also obtained in the CMT2A mouse model.
In conclusion, this study contributed to deepen the knowledge about disease molecular mechanisms, generating an in vitro model of CMT2A by patient-specific iPSCs, and to identify a possible therapeutic strategy for CMT2A.
Individuazione e tipizzazione polifasica di ecotipi funzionali di batteri lattici coinvolti nelle produzioni casearie italiane
Creators: name: BORGO, FRANCESCA CLAUDIA
Publisher: name: Universit� degli Studi di Milano
Year: 2008

description: This PhD thesis dealt with the phenotypic and genotypic characterization of LAB strains through a polyphasic taxonomic approach, molecular analyses such as PCR, ITS, ARDRA, the study of housekeeping genes, search and classification of plasmidic DNA. The integration of the phenotypic, biotechnological and genotypic results allowed the obtainment of fingerprinting specific at the strain-level and the possible discrimination of the strains in function of their ecological niches.
sj-docx-1-otj-10.1177_15394492221088511 – Supplemental material for Preferred Content in Occupational Therapy-Based Weight Loss Interventions: A Survey
Creators: name: Christensen, Jeanette Reffstrup
name: Konge, Maria B.
name: Devantier, Martin
name: Brandt, Carl J.
name: Gommesen, Joakim B.
name: Kolind, Mikkel I.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences

description: Supplemental material, sj-docx-1-otj-10.1177_15394492221088511 for Preferred Content in Occupational Therapy-Based Weight Loss Interventions: A Survey by Jeanette Reffstrup Christensen, Maria B. Konge, Martin Devantier, Carl J. Brandt, Joakim B. Gommesen and Mikkel I. Kolind in OTJR: Occupation, Participation and Health
Hybrid Total Feti Method
Creators: name: T. Kozubek
Publisher: name: Zenodo
Year: 2012
Subjects: hybrid FETI

description: We describe a hybrid FETI (Finite Element Tearing and Interconnecting) method based on our variant of the FETI

type domain decomposition method called Total FETI. In our approach a small number of neighboring subdomains is

aggregated into the clusters, which results into a smaller coarse problem. To solve the original problem the Total FETI

method is applied twice: to the clusters (macro-subdomains) and then to the subdomains in each cluster. This approach

simplifies implementation of hybrid FETI methods and enables to extend parallelization of the original problem up to

tens of thousands of cores due to the coarse space reduction and thus lower memory requirements. The performance is

demonstrated on a linear elasticity benchmark.

Keywords Domain decomposition, Total FETI, Hybrid FETI, scalable algorithm.
Additional file 1 of Combined associations of visceral adipose tissue and adherence to a Mediterranean lifestyle with T2D and diabetic microvascular complications among individuals with prediabetes
Creators: name: Chen, Hao-Wen
name: Liu, Kuan
name: Cao, Bi-Fei
name: Zhong, Qi
name: Zhou, Rui
name: Li, Liang-Hua
name: Wang, Shi-Ao
name: Wei, Yan-Fei
name: Liu, Hua-Min
name: Wu, Xian-Bo
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology
subject: Virology

description: Supplementary Material 1
sj-pdf-1-dem-10.1177_14713012221093879 – Supplemental Material “Am I entitled to take a break in caregiving?”: Perceptions of leisure activities of family caregivers of loved ones with dementia in China
Creators: name: Xu, Xin Yi
name: Leung, Doris
name: Leung, Angela Yee Man
name: Kwan, Rick Yiu Cho
name: Liang, Ting Na
name: Chai, Ai Jun
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111099 Nursing not elsewhere classified
subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 160512 Social Policy
subject: FOS: Political science

description: Supplemental Material, sj-pdf-1-dem-10.1177_14713012221093879 for “Am I entitled to take a break in caregiving?”: Perceptions of leisure activities of family caregivers of loved ones with dementia in China by Xin Yi Xu, Rick Yiu Cho Kwan, Ting Na Liang, Doris Leung, Ai Jun Chai and Angela Yee Man Leung in Dementia
Economia circolare: il concetto, applicazioni pratiche, modelli di business e casi aziendali
Creators: name: Turco, Gabriele
Publisher: name: Academia.edu
Year: 2019
Subjects: subject: Economics
subject: Sustainable development

description: Elaborato realizzato per il corso di Economia dell'Ambiente tenuto dal prof. Pietro Rostirolla. L'elaborato tratta del concetto di Economia circolare e della sua evoluzione storica, alcune applicazioni pratiche, modelli di business e casi aziendali.
Additional file 2 of Palliative care research utilising intersectionality: a scoping review
Creators: name: Butler, Helen
name: Gott, Merryn
name: Prebble, Doctor Kate
name: Fortune, Doctor Sarah
name: Robinson, Doctor Jackie
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 2: Supplementary Table S1. CASP quality appraisal results for qualitative research included in literature review. Supplementary Table S2. AXIS quality appraisal results for quantitative research included in literature review.
Recent Advances in the Core-Annulation of Naphthalene Diimides
Creators: name: Insuasty Chamorro, Braulio
name: Maniam, Subashani
name: Langford, Steven
Publisher: name: Swinburne
Year: 2024

description: This review focuses on describing all known synthetic strategies leading to core-annulation of naphthalene diimides (NDIs). Strategies presented involve the formation of four-, five- and six-membered ring annulations bearing different heteroatomic and carbocyclic derivatives, including annulenes. The core-annulation method opens the possibility for obtaining designer molecules with tuneable electronic characteristics such as a reduced energy band gap, and enhanced intermolecular overlap of π-systems that improve electronic coupling between molecules—which is highly desirable for charge transport properties summarised in the final pages for applications in electronic devices such as organic field-effect transistors (OFETs) and organic photovoltaic (OPV) cells. Molecular recognition in pH and fluoride sensing, or as a DNA probe, are some of additional applications of core-annulated NDIs presented here. Additionally, recent advances in core modification of NDIs are presented, opening an entire new chemical avenue to be explored. Finally, the outlook on the future prospect of annulated NDIs in various applications is summarised.
Computational prediction of microRNAs in marine bacteria of the genus Thalassospira
Creators: name: Dang, Thi Hoang Yen
name: Tyagi, Sonika
name: D’Cunha, Glenn
name: Bhave, Mrinal
name: Crawford, Russell
name: Ivanova, Elena
Publisher: name: Swinburne
Year: 2024

description: MicroRNAs (miRNAs) are key players in regulation of gene expression at post-transcription level in eukaryotic cells. MiRNAs have been intensively studied in plants, animals and viruses. The investigations of bacterial miRNAs have gained less attention, except for the recent studies on miRNAs derived from Streptococcus mutans ATCC 25175 and Escherichia coli DH10B. In this study, high-throughput sequencing approach was employed to investigate the miRNA population in bacteria of the genus Thalassospira using both the miRDeep2 and CID-miRNA methods. A total of 984 putative miRNAs were identified in 9 species of the genus Thalassospira using both miRDeep and CID-miRNA analyses. Fifty seven conserved putative miRNAs were found in different species of the genus Thalassospira, and up to 6 miRNAs were found to be present at different locations in the T. alkalitolerans JCM 18968T, T. lucentensis QMT2T and T. xianhensis P-4T. None of the putative miRNAs was found to share sequence to the reported miRNAs in E. coli DH10B and S. mutans ATCC 25175. The findings provide a comprehensive list of computationally identified miRNAs in 9 bacterial species of the genus Thalassospira and addressed the existing knowledge gap on the presence of miRNAs in the Thalassospira genomes.
Additional file 1 of Bayesian estimation for the accuracy of three neuropsychological tests in detecting Alzheimer's disease and mild cognitive impairment: a retrospective analysis of the ADNI database
Creators: name: Wang, Xiaonan
name: Li, Fengjie
name: Tian, Jiang
name: Gao, Qi
name: Zhu, Huiping
Publisher: name: figshare
Year: 2024
Subjects: Biochemistry
Cell Biology
Neuroscience
Biotechnology
Chemical Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer
Mental Health

description: Additional file 1: Figure S1. Results of the Accuracy of Three Neuropsychological Tests in Detecting AD and MCI from Observed Data in ADNI.
Progetto ImmaginAzione
Creators: name: Cerrone, Vincenzo
name: Menditto, Clemente
name: Raia, Rossella
name: Scalella, Alessandro Mario
name: Spavone, Pier Davide
name: Turco, Gabriele
name: Vitale, Alessio
Publisher: name: Academia.edu
Year: 2020
Subjects: subject: Sustainability
subject: Sustainable development
subject: Urban ecology (Sociology)
subject: City planning
subject: Education
subject: Economics
subject: Public health

description: Questo è il progetto realizzato per l'hackaton 2020+20, svoltosi nell'ambito del Festival della Partecipazione di Bologna. L'obiettivo è immaginare lo scenario di un futuro desiderabile, in linea con le necessità del nostro tempo e con le necessità che crediamo saranno rilevanti nel futuro. Il progetto affronta i temi della relazione città campagna, cittadinanza e comunità, governo, istruzione, mobilità, sanità e ambiente, e prevede:

1. Analisi del contesto attuale
2. Scenario che si desidera realizzare nel 2040
3. Scenario intermedio al 2030
4. Azioni che le istituzioni e la cittadinanza devono porre in essere per passare dall'analisi del contesto attuale allo scenario 2030
5. Azioni che le istituzioni e la cittadinanza devono porre in essere per passare dallo scenario 2030 allo scenario 2040
description: Questo è il progetto realizzato per l'hackaton 2020+20, svoltosi nell'ambito del Festival della Partecipazione di Bologna. L'obiettivo è immaginare lo scenario di un futuro desiderabile, in linea con le necessità del nostro tempo e con le necessità che crediamo saranno rilevanti nel futuro. Il progetto affronta i temi della relazione città campagna, cittadinanza e comunità, governo, istruzione, mobilità, sanità e ambiente, e prevede: 1. Analisi del contesto attuale 2. Scenario che si desidera realizzare nel 2040 3. Scenario intermedio al 2030 4. Azioni che le istituzioni e la cittadinanza devono porre in essere per passare dall'analisi del contesto attuale allo scenario 2030 5. Azioni che le istituzioni e la cittadinanza devono porre in essere per passare dallo scenario 2030 allo scenario 2040
ALGORITHMS FOR THE LARGE-SCALE UNIT COMMITMENT PROBLEM IN THE SIMULATION OF POWER SYSTEMS
Creators: name: TAVERNA, ANDREA
Publisher: name: Universit� degli Studi di Milano
Year: 2017

description: Lo Unit Commitment Problem (UCP) � un problema di programmazione matematica dove un insieme di impianti termoelettrici deve essere programmato per soddisfare la domanda di energia e altri vincoli di sistema. Il modello � impiegato da decenni per supportare la pianificazione operazionale di breve termine dei sistemi elettrici.
In questo lavoro affrontiamo il problema di risolvere UCP lineari di larga-scala per realizzare simulazioni accurate di sistemi elettrici, con i requisiti aggiuntivi di impiegare capacit� di calcolo convenzionali, ad esempio i personal computers, ed un tempo di soluzione di poche ore. Il problema, sotto le medesime condizioni, � affrontato abitualmente dal nostro partner industriale RSE S.p.A. (Ricerche Sistema Energetico), uno dei principali centri ricerche industriali su sistemi energetici in Italia.
L?ottimizzazione diretta di queste formulazioni con solutori generici � impraticabile. Nonostante sia possibile calcolare buone soluzioni euristiche, ovvero con un gap di ottimalit� sotto il 10%, in tempi ragionevoli per UCP di larga scala, si richiedono soluzioni pi� accurate, per esempio con gap sotto l?1%, per migliorare l?affidabilit� delle simulazioni ed aiutare gli esperti di dominio, che potrebbero non essere familiari con i dettagli dei metodi di programmazione matematica, a supportare meglio le loro analisi.
Tra le idee che abbiamo esplorato i seguenti metodi risultano i pi� promettenti: una mateuristica per calcolare efficientemente buone soluzioni e due metodi esatti di bounding: column generation e Benders decomposition. Questi metodi decompongono il problema disaccoppiando il commitment degli impianti termoelettrici, rappresentati da variabili discrete, e il loro livello di produzione, rappresentato da variabili continue.
I nostri esperimenti dimostrano che il modello possiede propriet� intrinseche come degenerazione e forma della funzione obbiettivo piatta che ostacolano o impediscono la convergenza in risolutori allo stato dell?arte. Tuttavia, i metodi che abbiamo sviluppato, sfruttando efficacemente le propriet� strutturali del modello, permettono di raggiungere soluzioni quasi ottime in poche iterazioni per la maggior parte delle istanze.
Dynamic shear testing of 2024 T351 aluminium at elevated temperature
Creators: name: Edwards, Nathan J.
name: Kariem, Muhammad A.
name: Rahman Rashid, Rizwan Abdul
name: Cimpoeru, Stephen J.
name: Lu, Guoxing
name: Ruan, Dong
Publisher: name: Swinburne
Year: 2024

description: 2024-T351 aluminium hat-shaped specimens have been used to experimentally investigate the effect of different initial test temperatures on the strain at which a thermo-plastic instability occurs. A universal testing machine and split Hopkinson pressure bar (SHPB) were used to determine resolved shear stress—nominal plastic shear strain for specimens tested at room temperature, 125 °C and 250 °C, respectively. The shear strain rates was 2 × 10−3 for quasi-static tests and ranged between 5 × 103 to 17.8 × 103 s−1 for dynamic tests. Microstructural observations using optical, scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD) were presented to explain the observed mechanical properties. The flow stress of the 125 °C specimens tested at intermediate and high strain rate ( > 10 × 103 s−1) was higher than the flow stress of the room temperature specimens at the same rates. This is believed to be due to different precipitate types, leading to variable strain rate sensitivity as a function of temperature. No quantifiable effect of initial temperature on the strain at which the thermo-plastic instability occurs was identified.
STORY AND SOCIAL MEDIA: IDENTITIES AND INTERACTION
Creators: name: อุบลวรรณ เปรมศรีรัตน์
Publisher: name: คณะนิเทศศาสตร์และนวัตกรรมการจัดการ สถาบันบัณฑิตพัฒนบริหารศาสตร์
Year: 2557

description: วารสารนิเทศศาสตร์และนวัตกรรม นิด้า, 1, 1
LA COOPERAZIONE INVESTIGATIVA NELL'UE E LE GARANZIE DIFENSIVE DELL'ACCUSATO
Creators: name: METTICA, VALERIA FRANCESCA
Publisher: name: Universit� degli Studi di Milano
Year: 2016

description: Ricostruite le forme della cooperazione investigativa in materia penale nel panorama europeo, anche alla luce dei pi� recenti sviluppi, sembra potersi concludere che, sebbene gli indicatori normativi testimonino una volont� di integrazione di strutture e apparati al fine di imporre regole giuridiche tendenzialmente uniformi, la dimensione applicativa registra ancora un limitato intervento del diritto dell'Unione Europea sul piano processuale, confinandolo negli ambiti della cooperazione su base volontaria e del principio del mutuo riconoscimento, cos� di fatto esasperando le difficolt� operative del coordinamento investigativo e dello scambio di dati a contenuto probatorio.
Additional file 1 of Does hip protector prevent falls and hip fractures? An umbrella review of meta-analyses
Creators: name: Da, Qingchen
name: Xiao, Yingheng
name: Wu, Feng
name: Chen, Yueliang
name: Li, Liping
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Supplementary Material 1
title: An Investigation to Improve Linear Predictive Vocoder Pulse/Noise Excitation Models
Creators: name: Effer, Elizabeth Annella Martina
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1985

description: The quality of synthetic speech from Linear Predictive (LP) vocoders is known to be degraded due to the lack of detail in the commonly used pulse/noise excitation model. In this investigation, it was hypothesized that this degradation is due to the lack of precise timing information in the pulses and to the constraint that each short-time segment of excitation be either an impulse train or white noise. Accordingly, more complex excitation models were implemented using precise timing from peaks in the residual and a mixture of pulses and noise. Since the LP residual is known to be the perfect excitation signal for LP vocoders, these models were based on the LP residual. The timing was determined by locating peaks in a lowpass-filtered LP residual energy waveform. In order to determine the approximate mixture of pulses and noise, two methods were explored to separate the periodic and non-periodic components of the residual. One method, based on the assumption that the periodic and non-periodic components are separated in the frequency domain, employed linear filters to separate the two components. The second method, based on the assumption that the components are separated in the time domain, used time-domain techniques and the lowpass-filtered residual energy waveform to separate the two components. The time domain approach proved to be more feasible. Frequency domain models were developed for modeling the periodic pulse-like component and the non-periodic noise-like component such that the spectrum of the combined components would be flat. Listening experiments indicated that the precise timing of the periodic component resulted in improved quality synthetic speech. Improvements in speech quality related to modeling a mixture of pulses and noise in the excitation were much more difficult to obtain.
GREEN ACTION PRACTICE AND PERFORMANCE OF SMES IN ENUGU STATE
Creators: name: Unogu, Chisom Ndubuisi
name: Sunday, Ikechukwu Emmanuel
name: Onwumere, Francis Udokamma
Publisher: name: hollex journal
Year: 2025
Subjects: Green action, Performance, Waste generation & Compliance with regulations.

description: The study evaluated the green action practice and performance of SMEs in Enugu State. The specific objectives are to; examine the relationship between minimizing waste generation and operational efficiency; and ascertain the relationship between compliance with regulations and customer purchases of SMEs in Enugu State.  The area of the study was Enugu State. The study used the descriptive survey design approach. The primary source of data was the administration of questionnaire. A total population of 257 selected owners and employees of the study organizations were used. The whole population was used to due small number. Two hundred and forty eight (248) respondents returned the questionnaire and accurately filled. Data was presented and analyzed using Likert Scale and the hypotheses using Z – test.  The findings indicated that there was significant positive relationship between minimizing waste generation and operational efficiency of SMEs in Enugu State, Z = 9.608, P. = 0.05. There was significant positive relationship between compliance with regulations and customer purchases of SMEs in Enugu State, Z = 9.878, P. 0 .05. The study concluded that minimizing waste generation and compliance with regulations had significant positive relationship with operational efficiency and regulations and customer purchases of SMEs in Enugu State. The study recommended that Firms should Implement Lean Manufacturing Practices which include the 5S methodology Sort, Set in Order, Shine, Standardize, Sustain) to organize the workspace and minimize waste, this will to reduce costs, improve sustainability, and boost profitability
Additional file 2 of Does hip protector prevent falls and hip fractures? An umbrella review of meta-analyses
Creators: name: Da, Qingchen
name: Xiao, Yingheng
name: Wu, Feng
name: Chen, Yueliang
name: Li, Liping
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Supplementary Material 2
Additional file 1 of Ginseng-derived nanoparticles reprogram macrophages to regulate arginase-1 release for ameliorating T cell exhaustion in tumor microenvironment
Creators: name: Lv, Yan
name: Li, Mengyuan
name: Weng, Ling
name: Huang, Haoying
name: Mao, Yujie
name: Yang, Danchen Aaron
name: Wei, Qingyun
name: Zhao, Mengmeng
name: Wei, Qin
name: Rui, Ke
name: Han, Xuan
name: Fan, Weiwei
name: Cai, Xueting
name: Cao, Peng
name: Cao, Meng
Publisher: name: figshare
Year: 2023
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1. Supplemental materials and methods [56–60].
sj-docx-1-tar-10.1177_17534666221086416 – Supplemental material for Caregiver burden in cystic fibrosis: a systematic literature review
Creators: name: Daly, Conor
name: Ruane, Philip
name: O’Reilly, Karl
name: Longworth, Louise
name: Vega-Hernandez, Gabriela
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 110203 Respiratory Diseases

description: Supplemental material, sj-docx-1-tar-10.1177_17534666221086416 for Caregiver burden in cystic fibrosis: a systematic literature review by Conor Daly, Philip Ruane, Karl O’Reilly, Louise Longworth and Gabriela Vega-Hernandez in Therapeutic Advances in Respiratory Disease
H i galaxies with little star formation: An abundance of LIERs
Creators: name: Parkash, Vaishali
name: Brown, Michael J.I.
name: Jarrett, T. H.
name: Fraser-Mckelvie, A.
name: Cluver, Michelle
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: We present a sample of 91 H i galaxies with little or no star formation, and discuss the analysis of the integral field unit (IFU) spectra of 28 of these galaxies. We identified H i galaxies from the H i Parkes All-Sky Survey Catalog (HICAT) with Wide-field Infrared Survey Explorer (WISE) colours consistent with low specific star formation (<10−10.4 yr−1), and obtained optical IFU spectra with the Wide-Field Spectrograph (WiFeS). Visual inspection of the PanSTARRS, Dark Energy Survey, and Carnegie-Irvine imaging of 62 galaxies reveals that at least 32 galaxies in the sample have low levels of star formation, primarily in arms/rings. New IFU spectra of 28 of these galaxies reveals 3 galaxies with central star formation, 1 galaxy with low-ionization nuclear emission-line regions (LINERs), 20 with extended low-ionization emission-line regions (LIERs), and 4 with high excitation Seyfert (Sy) emission. From the spectroscopic analysis of H i selected galaxies with little star formation, we conclude that 75 per cent of this population are LINERs/LIERs.
Additional file 1 of Epithelium-derived exosomes promote silica nanoparticles-induced pulmonary fibroblast activation and collagen deposition via modulating fibrotic signaling pathways and their epigenetic regulations
Creators: name: Li, Yan
name: Xu, Hailin
name: Wang, Ying
name: Zhu, Yurou
name: Xu, Kun
name: Yang, Zhu
name: Li, Yanbo
name: Guo, Caixia
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file1.
Relativistic Spin Precession in the Binary PSR J1141-6545
Creators: name: Venkatraman Krishnan, V.
name: Bailes, Matthew
name: van Straten, Willem
name: Keane, Evan
name: Kramer, M.
name: Bhat, N. D. R.
name: Flynn, Christopher
name: Oslowski, Stefan
Publisher: name: Swinburne
Year: 2024

description: PSR J1141-6545 is a precessing binary pulsar that has the rare potential to reveal the two-dimensional structure of a non-recycled pulsar emission cone. It has undergone similar to 25 degrees of relativistic spin precession in the similar to 18 yr since its discovery. In this Letter, we present a detailed Bayesian analysis of the precessional evolution of the width of the total intensity profile, in order to understand the changes to the line-of-sight (LOS) impact angle (beta) of the pulsar using four different physically motivated prior distribution models. Although we cannot statistically differentiate between the models with confidence, the temporal evolution of the linear and circular polarizations strongly argue that our LOS crossed the magnetic pole around MJD 54,000 and that only two models remain viable. For both of these models, it appears likely that the pulsar will precess out of our LOS in the next 3-5 yr, assuming a simple beam geometry. Marginalizing over beta suggests that the pulsar is a near-orthogonal rotator and provides the first polarization-independent estimate of the scale factor (A) that relates the pulsar beam opening angle (rho) to its rotational period (P) as rho = AP(-0.5): we find it to be >6 degrees s(0.5) at 1.4 GHz with 99% confidence. If all pulsars emit from opposite poles of a dipolar magnetic field with comparable brightness, we might expect to see evidence of an interpulse arising in PSR J1141-6545, unless the emission is patchy.
UVC Stokes and Anti-Stokes Emission of Ca9Y(PO4)7 Polycrystals Doped with Pr3+ Ions
Creators: name: Lemański, Karol
name: Bezkrovna, Olha
name: Rebrova, Nadiia
name: Lisiecki, Radosław
name: Zdeb-Stańczykowska, Patrycja
name: Dereń, Przemysław Jacek
Publisher: name: Zenodo
Year: 2025

description: Abstract: The recent COVID-19 pandemic has made everyone aware of the threat of viruses and thegrowing number of antibiotic-resistant bacteria. It has become necessary to find new methods tocombat these hazards. One tool that could be used is UVC radiation, i.e., 100–280 nm. Currently, theavailable sources of this light are mercury vapor lamps. However, the modern world requires morecompact, mercury-free, and less energy-consuming light sources. This work presents the results ofour research on a new material in which efficient UVC radiation was obtained. Here, we present theresults of research on Ca9Y(PO4)7 polycrystals doped with Pr3+ ions prepared using the solid-statemethod. The absorption, excitation, emission, and emission decay profiles of praseodymium(III)ions were measured and analyzed. The upconversion emission in the UVC region excited by bluelight was observed. Parameters such as energy bandgap, refractive index, and thermal stabilityof luminescence were determined. The studied phosphate-based phosphor possesses promisingcharacteristics that show its potential in luminescent applications in future use in medicine or forsurface disinfection.
Additional file 3 of Ginseng-derived nanoparticles reprogram macrophages to regulate arginase-1 release for ameliorating T cell exhaustion in tumor microenvironment
Creators: name: Lv, Yan
name: Li, Mengyuan
name: Weng, Ling
name: Huang, Haoying
name: Mao, Yujie
name: Yang, Danchen Aaron
name: Wei, Qingyun
name: Zhao, Mengmeng
name: Wei, Qin
name: Rui, Ke
name: Han, Xuan
name: Fan, Weiwei
name: Cai, Xueting
name: Cao, Peng
name: Cao, Meng
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 3: Table S1. Antibodies used for flow cytometry, western blot. Table S2. Drug information. Table S3. Experimental Models: Cell Lines. Table S4. Primer sequences for real-time RT-PCR analysis. Table S5. Effector function gene set.
Black Hole Mass Scaling Relations for Spiral Galaxies. I. M BH -M ∗,sph
Creators: name: Davis, Benjamin
name: Graham, Alister
name: Cameron, Ewan
Publisher: name: Swinburne
Year: 2024

description: The (supermassive black hole mass, M-BH)-(bulge stellar mass, M-*,M-sph) relation is, obviously, derived using two quantities. We endeavor to provide accurate values for the latter via detailed multicomponent galaxy decompositions for the current full sample of 43 spiral galaxies having directly measured M-BH values; 35 of these galaxies have been alleged to contain pseudobulges, 21 have water maser measurements, and three appear bulgeless. This more than doubles the previous sample size of spiral galaxies with a finessed image analysis. We have analyzed near-infrared images, accounting for not only the bulge, disk (exponential, truncated, or inclined), and bar but also spiral arms and rings and additional central components (active galactic nuclei (AGNs), etc.). A symmetric Bayesian analysis finds log (M-BH/M-circle dot) = (2.44(-0.31)(+0.35)) log {M-*,M-sph/[v(1.15 X 10(10) M-circle dot)]} + (7.24 +/- 0.12), with v a stellar mass-to-light ratio term. The level of scatter equals that about the M-BH-sigma(*) relation. The nonlinear slope rules out the idea that many mergers, coupled with the central limit theorem, produced this scaling relation, and it corroborates previous observational studies and simulations, which have reported a near-quadratic slope at the low-mass end of the M-BH-M-*,M-sph diagram. Furthermore, bulges with AGNs follow this relation; they are not offset by an order of magnitude, and models that have invoked AGN feedback to establish a linear M-BH-M-*,M-sph relation need revisiting. We additionally present an updated M-BH-(Sersic index, n(sph)) relation for spiral galaxy bulges with a comparable level of scatter and a new M-BH-M-*,M-sph-(spiral-arm pitch angle, phi) relation.
Additional file 1 of Blood biomarkers and neurodegeneration in individuals exposed to repetitive head impacts
Creators: name: Bernick, Charles
name: Shan, Guogen
name: Ritter, Aaron
name: Ashton, Nicholas J.
name: Blennow, Kaj
name: Lantero-Rodriguez, Juan
name: Snellman, Anniina
name: Zetterberg, Henrik
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health

description: Additional file 1: Fig. S3. Relationship between baseline GFAP (measured in pg/mL) and MRI volume measurements (in mm3) of the thalamus, hippocampus, and total gray matter, along with processing speed (computed from number of correct responses on Symbol Digit Coding test minus errors)
Anisotropy of the Milky Way's Stellar Halo Using K Giants from LAMOST and Gaia
Creators: name: Bird, Sarah A.
name: Xue, Xiang-Xiang
name: Liu, Chao
name: Shen, Juntai
name: Flynn, Christopher
name: Yang, Chengqun
Publisher: name: Swinburne
Year: 2024

description: The anisotropy parameter beta characterizes the extent to which orbits in stellar systems are predominantly radial or tangential and is likely to constrain, for the stellar halo of the Milky Way, scenarios for its formation and evolution. We have measured beta as a function of Galactocentric radius from 5 to 100 kpc for 7664 metal-poor ([Fe/H] < -1.3) halo K giants from the LAMOST catalog with line-of-sight velocities and distances, matched to proper motions from the second Gaia data release. We construct full 6D positions and velocities for the K giants to directly measure the three components of the velocity dispersion (sigma(r), sigma(theta), sigma(phi)) (in spherical coordinates). We find that the orbits in the halo are radial over our full Galactocentric distance range reaching over 100 kpc. The anisotropy remains remarkably unchanged with Galactocentric radius from approximately 5-25 kpc, with an amplitude that depends on the metallicity of the stars, dropping from beta approximate to 0.9 for -1.8 <= [Fe/H]< -1.3 (for the bulk of the stars) to beta approximate to 0.6 for the lowest metallicities ([Fe/H]< -1.8). Considering our sample as a whole, beta approximate to 0.8 and beyond 25 kpc, the orbits gradually become less radial and anisotropy decreases to beta < 0.3 past 100 kpc. Within 8 kpc, beta < 0.8. The measurement of anisotropy is affected by substructure and streams, particularly beyond a Galactocentric distance of approximately 25 kpc, where the Sagittarius stream is prominent in the data. These results are complimentary to recent analysis of simulations by Loebman et al. and of SDSS/Gaia DR1 data by Belokurov et al.
sj-pdf-2-cmp-10.1177_07388942221077926 - Supplemental material for {peacesciencer}: An R package for quantitative peace science research†
Creators: name: Miller, Steven V
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 220104 Human Rights and Justice Issues
subject: FOS: Philosophy, ethics and religion
subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-pdf-2-cmp-10.1177_07388942221077926 for {peacesciencer}: An R package for quantitative peace science research† by Steven V Miller in Conflict Management and Peace Science
ก้าวที่ผ่านมาและก้าวต่อไปของการสื่อสารชุมชน: ตอนที่ 2 การศึกษาการสื่อสารชุมชนในรูปแบบใหม่
Creators: name: กำจร หลุยยะพงศ์
Publisher: name: คณะนิเทศศาสตร์และนวัตกรรมการจัดการ สถาบันบัณฑิตพัฒนบริหารศาสตร์
Year: 2558

description: วารสารนิเทศศาสตร์และนวัตกรรม นิด้า, 2, 1
Additional file 1 of Inhibiting NR5A2 targets stemness in pancreatic cancer by disrupting SOX2/MYC signaling and restoring chemosensitivity
Creators: name: Zheng, Quan
name: Tang, Jiajia
name: Aicher, Alexandra
name: Bou Kheir, Tony
name: Sabanovic, Berina
name: Ananthanarayanan, Preeta
name: Reina, Chiara
name: Chen, Minchun
name: Gu, Jian-Min
name: He, Bin
name: Alcala, Sonia
name: Behrens, Diana
name: Lawlo, Rita T.
name: Scarpa, Aldo
name: Hidalgo, Manuel
name: Sainz, Bruno
name: Sancho, Patricia
name: Heeschen, Christopher
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 1: Supplementary Table 1. cDNA primer sequences. Supplementary Table 2. Genomic DNA primer sequences. Supplementary Table 3. Genetic targeting of NR5A2.
ODISSEI User Policy
Creators: name: Braukmann, Ricarda
name: Emery, Tom
name: van der Meer, Lucas
Publisher: name: Zenodo
Year: 2021
Subjects: Policy
FAIR data
Open Science
FACT

description: ODISSEI is the Open Data Infrastructure for Social Science and Economic Innovations in the Netherlands. The ODISSEI User Policy sets out the ‘Terms of Participation’ for individuals at a ODISSEI Member Organization who wish to use a service provided by the ODISSEI infrastructure. The policy covers legal and ethical requirements, as well as code of conducts users are expected to adhere to. The policy further outlines expectations regarding FAIR Data and Open Science practices.
title: Integrating adventure therapy interventions with community-based mental health support: A scoping review
Creators: name: Dr Lee Hogan
name: Jackson, Mike
name: Ernst-Williams, Niels
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Psychiatry and Psychology
subject: Psychiatric and Mental Health
subject: Medicine and Health Sciences
subject: Counseling
subject: Mental and Social Health
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Sociology
subject: FOS: Sociology
subject: Adventure therapy integration

description: The objective of this scoping review is to understand the extent and type of evidence available regarding the integration of adventure therapy interventions with community-based mental health support.
Expected intermediate mass black holes in the Virgo cluster. II. Late-type galaxies
Creators: name: Graham, Alister
name: Soria, Roberto
name: Davis, Benjamin
Publisher: name: Swinburne
Year: 2024

description: The Chandra X-ray Observatory's Cycle 18 Large Program titled 'Spiral galaxies of the Virgo Cluster' will image 52 galaxies with the ACIS-S detector. Combined with archival data for an additional 22 galaxies, this will represent the complete sample of 74 spiral galaxies in the Virgo cluster with star formation rates greater than or similar to 0.3 M(circle dot)yr(-1). Many of these galaxies are expected to have an active nucleus, signalling the presence of a central black hole. In preparation for this survey, we predict the central black hole masses using the latest black hole scaling relations based on the spiral arm pitch angle phi, velocity dispersion sigma, and total stellar mass M-*,(galaxy).With a focus on intermediate-mass black holes (IMBHs; 10(2) < M-bh/M-circle dot < 10(5)), we highlight NGC 4713 and NGC 4178, both with M-bh approximate to 10(3)-10(4)(an estimate that is further supported in NGC 4178 by its nuclear star cluster mass). From Chandra archival data, we find that both galaxies have a point-like nuclear X-ray source, with unabsorbed 0.3-10 keV luminosities of a few times 10(38) erg s(-1). In NGC 4178, the nuclear source has a soft, probably thermal, spectrum consistent with a stellar-mass black hole in the high/soft state, while no strong constraints can be derived for the nuclear emission of NGC 4713. In total, 33 of the 74 galaxies are predicted to have M-bh < (10(5)-10(6)) M-circle dot, and several are consistently predicted to have masses of 10(4)-10(5) M-circle dot, such as IC 3392, NGC 4294, and NGC 4413. We speculate that a sizeable population of IMBH s may reside in late-type spiral galaxies with low stellar mass (M-* less than or similar to 10(10)M(circle dot)).
Tabela da co-ocorrência de palavras chave na pesquisa a partir do tratamento no Vosviewer-versao 2-aplicação do Tesauro
Creators: name: Cleyton Paes Gandra, Valquer
Publisher: name: Zenodo
Year: 2025
Subjects: subject: research data management
subject: Open science
subject: Open Access Publishing

description: Planilha de dados tabulados e categorizados, sendo por três colunas, uma denominada "keywords", "ocorruences", total link strength". Esses dados foram padronizados após a aplicação de um tesauro para normalização das nomeclaturas.

Glossário da tabela:ID - Identificação da palavra chave de acordo com uma lista desenvolvida a partir da coleta de dados e tratamento pelo VosViewer.

KeyWords - Palavras chave identificadas nos campos de título e abstract do artigos coletados na base de dados.

Occurrences- Apresenta o número  de documentos nas quais uma palavra chave ocorre.

Total Link Strenght- Há dois atributos de peso padrão, chamados de atributo Links e Total link strength. Para um determinado item, os atributos Links e Força total do link indicam, respectivamente, o número de links de um item com outros itens e a força total dos links de um item com outros itens.
The UVES Spectral Quasar Absorption Database (SQUAD) data release 1: The first 10 million seconds
Creators: name: Murphy, Michael
name: Kacprzak, Glenn
name: Savorgnan, Giulia A. D.
name: Carswell, Robert F.
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: We present the first data release (DR1) of the LIVES Spectral Quasar Absorption Database (SQUAD), comprising 467 fully reduced, continuum-fitted high-resolution quasar spectra from the Ultraviolet and Visual Echelle Spectrograph (LIVES) on the European Southern Observatory's Very Large Telescope. The quasars have redshifts z = 0-5, and a total exposure time of 10 million seconds provides continuum-to-noise ratios of 4-342 (median 20) per 2.5 km s(-1) pixel at 5500 angstrom. The SQUAD spectra are fully reproducible from the raw, archival LIVES exposures with open-source software, including our UVES_POPLER tool for combining multiple extracted echelle exposures which we document here. All processing steps are completely transparent and can be improved upon or modified for specific applications. A primary goal of SQUAD is to enable statistical studies of large quasar and absorber samples, and we provide tools and basic information to assist three broad scientific uses: studies of damped Lyman-alpha systems (DLAs), absorption-line surveys, and time-variable absorption lines. For example, we provide a catalogue of 155 DLAs whose Lyman-alpha lines are covered by the DR1 spectra, 18 of which are reported for the first time. The H I column densities of these new DLAs are measured from the DR1 spectra. DR1 is publicly available and includes all reduced data and information to reproduce the final spectra.
Additional file 1 of Compare the efficacy of antifungal agents as primary therapy for invasive aspergillosis: a network meta-analysis
Creators: name: Liu, Ao
name: Xiong, Liubo
name: Wang, Lian
name: Zhuang, Han
name: Gan, Xiao
name: Zou, Mengying
name: Wang, Xiaoming
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Additional file 2 of Inhibiting NR5A2 targets stemness in pancreatic cancer by disrupting SOX2/MYC signaling and restoring chemosensitivity
Creators: name: Zheng, Quan
name: Tang, Jiajia
name: Aicher, Alexandra
name: Bou Kheir, Tony
name: Sabanovic, Berina
name: Ananthanarayanan, Preeta
name: Reina, Chiara
name: Chen, Minchun
name: Gu, Jian-Min
name: He, Bin
name: Alcala, Sonia
name: Behrens, Diana
name: Lawlo, Rita T.
name: Scarpa, Aldo
name: Hidalgo, Manuel
name: Sainz, Bruno
name: Sancho, Patricia
name: Heeschen, Christopher
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 2: Figure S1. NR5A2 is overexpressed in pancreatic cancer stem cells. Figure S2. NR5A2 regulates proliferation of differentiated PDAC cells. Figure S3. NR5A2 controls stemness in PDAC. Figure S4. Inhibition of NR5A2 specifically eliminates tumor-initiating CSCs. Figure S5. NR5A2 promotes stemness by diminishing MYC expression. Figure S6. NR5A2 inhibition targets CSCs in vivo and extends survival in preclinical PDAC models.
57298: Photograph of sailors on HMS Queen Elizabeth
Creators: name: Project Team, Great War Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Photograph of sixteen sailors on the deck of the battleship HMS Queen Elizabeth. Propped in front of them is a life ring, inside which is sitting a dog. Part of a collection relating to Frank Harold Elletson, Royal Marine Artillery. Date uncertain, but the collection is described as including: "Diary [photo scrapbook] of HMS Queen Elizabeth, January to May 1915, plus photographs c. 1918".