cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
IL-10 plays a central regulatory role in the cytokines induced by hepatitis C virus core protein and polyinosinic acid:polycytodylic acid
Creators: name: Pang, Xiaoli
name: Zhang, Qianqian
name: Li, Tiangyang
name: Niu, Junqi
name: Su, Lishan
name: Li, Haijun
name: Song, Hongxiao
name: Zhai, Naicui
name: Zhang, Yujiao
name: Wang, Zhaoxia
name: Tu, Zhengkun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Hepatitis C virus (HCV) can cause persistent infection and chronic liver disease, and viral factors are involved in HCV persistence. HCV core protein, a highly conserved viral protein, not only elicits an immunoresponse, but it also regulates it. In addition, HCV core protein interacts with toll-like receptors (TLRs) on monocytes, inducing them to produce cytokines. Polyinosinic acid:polycytodylic acid (polyI:C) is a synthetic analogue of double-stranded RNA that binds to TLR3 and can induce secretion of type I IFN from monocytes. Cytokine response against HCV is likely to affect the natural course of infection as well as HCV persistence. However, possible effects of cytokines induced by HCV core protein and polyI:C remain to be investigated. In this study, we isolated CD14+ monocytes from healthy donors, cultured them in the presence of HCV core protein and/or polyI:C, and characterized the induced cytokines, phenotypes and mechanisms. We demonstrated that HCV core protein- and polyI:C-stimulated CD14+ monocytes secreted tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-10, and type I interferon (IFN). Importantly, TNF-α and IL-1β regulated the secretion of IL-10, which then influenced the expression of signal transducer and activator of transcription 1 (STAT1) and interferon regulatory factor 1 (IRF1) and subsequently the production of type I IFN. Interestingly, type I IFN also regulated the production of IL-10, which in turn inhibited the nuclear factor (NF)-κB subunit, reducing TNF-α and IL-1β levels. Therefore, IL-10 appears to play a central role in regulating the production of cytokines induced by HCV core protein and polyI:C.
Elastic nucleon-pion scattering at $m_{\pi} \approx 200~{\rm MeV}$ from lattice QCD
Creators: name: Bulava, John
name: Hanlon, Andrew D.
name: Hörz, Ben
name: Morningstar, Colin
name: Nicholson, Amy
name: Romero-López, Fernando
name: Skinner, Sarah
name: Vranas, Pavlos
name: Walker-Loud, André
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2022
Subjects: error, statistical
expansion, effective range
quark, mass
quark, flavor
lattice field theory
scattering length
finite size
partial wave
Delta(1232)
excited state
scattering amplitude
energy levels
gauge field theory
lattice
isospin
scattering
lattice QCD
scattering amplitudes

description: Elastic nucleon-pion scattering amplitudes are computed using lattice QCD on a single ensemble of gauge field configurations with $N_f = 2+1$ dynamical quark flavors and $m_{\pi}$ = 200 MeV. The $s$-wave scattering lengths with both total isospins $I=1/2$ and $I=3/2$ are inferred from the finite-volume spectrum below the inelastic threshold together with the $I=3/2$ $p$-wave containing the $\Delta(1232)$ resonance. The amplitudes are well-described by the effective range expansion with parameters constrained by fits to the finite-volume energy levels enabling a determination of the $I=3/2$ scattering length with statistical errors below $5\%$, while the $I = 1/2$ is somewhat less precise. Systematic errors due to excited states and the influence of higher partial waves are controlled, providing a pathway for future computations down to the physical light quark masses with multiple lattice spacings and physical volumes.
Ruha Benjamin, Race After Technology: Abolitionist Tools for the New Jim Code, Polity, 2019
Creators: name: Menéndez-Blanco, María
Publisher: name: Tecnoscienza – Italian Journal of Science & Technology Studies
Year: 2020

description: Tecnoscienza – Italian Journal of Science & Technology Studies, Vol. 11 No. 1 (2020): Tecnoscienza Nr. 21 – Anniversary Issue
Robustness of NIR calibrations for assessing fruit quality
Creators: name: Guthrie, John Austin
Publisher: name: CQUniversity
Year: 2022
Subjects: Food sciences not elsewhere classified

description: Predictive models based on near infra-red spectroscopy for the assessment of fruit internal quality attributes must exhibit a degree of robustness across the parameters of variety, district and time to be of practical use in fruit grading. At the time this thesis was initiated, while there were a number of published reports on the development of near infra-red based calibration models for the assessment of internal quality attributes of intact fruit, there were no reports of the reliability ("robustness") of such models across time, cultivars or growing regions. As existing published reports varied in instrumentation employed, a re-analysis of existing data was not possible. An instrument platform, based on partial transmittance optics, a halogen light source and a (Zeiss MMS1) detector operating in the short wavelength near infra-red region was developed for use in the assessment of intact fruit. This platform was used to assess populations of macadamia kernels, melons and mandarin fruit for total soluble solids, dry matter and oil concentration. Calibration procedures were optimised and robustness assessed across growing areas, time of harvest, season and variety. In general, global modified partial least squares regression (MPLS) calibration models based on derivatised absorbance data were better than either multiple linear regression or 'local' MPLS models in the prediction of independent validation populations. Robustness was most affected by growing season, relative to the growing district or variety. Various calibration updating procedures were evaluated in terms of calibration robustness. Random selection of samples from the validation population for addition to the calibration population was equivalent to or better than other methods of sample addition (methods based on the Mahalanobis distance of samples from either the centroid of the population or neighbourhood samples). In these exercises the global Mahalanobis distance (GH) was calculated using the scores and loadings from the calibration population on the independent validation population. In practice, it is recommended that model predictive performance be monitored in terms of predicted sample GH, with model updating using as few as 10 samples from the new population undertaken when the average GH value exceeds 1.0.
An STS Perspective on Pandemic
Creators: name: Viteritti, Assunta
Publisher: name: Tecnoscienza – Italian Journal of Science & Technology Studies
Year: 2020

description: What can STS say about the pandemic? What kind of scientific models do we need to question our time? In this reflection I envision three issues which seem to me of particular importance: (1) the “social” as a result of sociomaterial associations; 2) science as an open-air laboratory; 3) the new forms of alliances between science and politics. I conclude focusing on the theme of interdisciplinarity, the major challenge that the pandemic poses to science.
description: Tecnoscienza – Italian Journal of Science & Technology Studies, Vol. 11 No. 1 (2020): Tecnoscienza Nr. 21 – Anniversary Issue
Supplementary Text from An evolutionary game model of individual choices and bed net use: elucidating key aspect in malaria elimination strategies
Creators: name: Laxmi, Bhati
name: Ngonghala, Calistus N
name: Bhattacharyya, Samit
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences
subject: Computational Biology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Insecticide-treated net (ITN) is the most applicable and cost-effective malaria intervention measure in sub-Saharan Africa and elsewhere. Although ITNs have been widely distributed to malaria-endemic regions in the past, their success has been threatened by misuses (in fishing, agriculture etc.) and decay in ITN-efficacy. Decision-making in using the ITNs depends on multiple coevolving factors: malaria prevalence, mosquito density, ITN availability and its efficacy, and other socio-economic determinants. While ITN-misuse increases as the efficacy of ITNs declines, high efficacy also impedes proper use due to free-riding. This irrational usage leads to increased malaria prevalence, thereby worsening malaria control efforts. It also remains unclear if the optimum ITN use for malaria elimination can be achieved under such an adaptive social learning process. Here, we incorporate evolutionary game theory into a disease transmission model to demonstrate these behavioural interactions and their impact on malaria prevalence. We show that social optimum usage is a function of transmission potential, ITN efficacy and mosquito demography. Under specific parameter regimes, our model exhibits patterns of ITN usage similar to observed data from parts of Africa. Our study suggests that the provision of financial incentives as prompt feedback to improper ITN-use can reduce misuse and contribute positively towards malaria elimination efforts in Africa and elsewhere.
T-regulatory cells and vaccination “pay attention and do not neglect them”: Lessons from HIV and cancer vaccine trials
Creators: name: Cheng, Liang
name: Su, Lishan
name: Seddiki, Nabila
name: Lévy, Yves
name: Brezar, Vedran
name: Godot, Véronique
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Efficient vaccines are characterized by the establishment of long-lived memory T cells, including T-helper (effectors and follicular) and T-regulatory cells (Tregs). While the former induces cytotoxic or antibody responses, the latter regulates immune responses by maintaining homeostasis. The role of Tregs in inflammatory conditions is ambiguous and their systematic monitoring in vaccination along with effector T-cells is not instinctive. Recent studies from the cancer field clearly showed that Tregs suppress vaccine-induced immune responses and correlate with poor clinical benefit. In HIV infection, Tregs are needed during acute infection to preserve tissue integrity from an overwhelmed activation, but are not beneficial in chronic infection as they suppress anti-HIV responses. Current assays used to evaluate vaccine-induced specific responses are limited as they do not take into account antigen-specific Tregs. However, new assays, such as the OX40 assay, which allow for the simultaneous detection of a full range of Th-responses including antigen-specific Tregs responses, can overcome these issues. In this review article we will revise the role of Tregs in vaccination and review the recent work performed in the field, including the available tools to monitor them, from novel assays to humanized mouse models.
A note on cutting spin networks and the area spectrum in loop quantum gravity
Creators: name: Asato, Yu
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, I show that if a spin network is cut by a surface separating space-time into two regions, the sum of spins of edges crossing the surface must be an integer. This gives a restriction on the area spectrum of such surfaces, including black hole horizons, in loop quantum gravity.
description: 7 pages with 2 figures; v2: added references; v3: added discussion of a sufficient condition, generalization, some clearer explanations, and more references
Plasmacytoid dendritic cells promote HIV-1-induced group 3 innate lymphoid cell depletion
Creators: name: Cheng, Liang
name: Su, Lishan
name: Wang, Fu-Sheng
name: Zhang, Zheng
name: Chen, Weiwei
name: Reszka-Blanco, Natalia J.
name: Zhao, Juanjuan
name: Zhang, Liguo
name: Li, Guangming
name: Nie, Weiming
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Group 3 innate lymphoid cells (ILC3s) have demonstrated roles in promoting antibacterial immunity, maintaining epithelial barrier function, and supporting tissue repair. ILC3 alterations are associated with chronic inflammation and inflammatory disease; however, the characteristics and relevant regulatory mechanisms of this cell population in HIV-1 infection are poorly understood due in part to a lack of a robust model. Here, we determined that functional human ILC3s develop in lymphoid organs of humanized mice and that persistent HIV-1 infection in this model depletes ILC3s, as observed in chronic HIV-1-infected patients. In HIV-1-infected mice, effective antiretroviral therapy reversed the loss of ILC3s. HIV-1-dependent reduction of ILC3s required plasmacytoid dendritic cells (pDCs), IFN-I, and the CD95/FasL pathway, as targeted depletion or blockade of these prevented HIV-1-induced ILC3 depletion in vivo and in vitro, respectively. Finally, we determined that HIV-1 infection induces CD95 expression on ILC3s via a pDC-and IFN-I-dependent mechanism that sensitizes ILC3s to undergo CD95/FasL-mediated apoptosis. We conclude that chronic HIV-1 infection depletes ILC3s through pDC activation, induction of IFN-I, and CD95-mediated apoptosis.
Doryopteris rediviva Fee, Crypt. Vasc.
Creators: name: Yesilyurt, Jovita Cislinski
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Pteridaceae
Doryopteris
Doryopteris rediviva

description: Doryopteris rediviva Fée, Crypt. Vasc. Brésil 2: 30, t. 89, fig. 1.1872.
 Protologue citation: “Habitat in Brasillia fluminensi (Tijuca, Glaziou n. 5341)”.
 Lectotype (designated here):— BRAZIL. [Rio de Janeiro]: “Rio [de Janeiro] a Tijuca”, Glaziou 5341 (P00507800!; isolectotypes: P [3 sheets]!, B 20 051586!; possible isolectotype: C!).
 Four specimens of Glaziou 5341 at P are referable to this species and all agree with the protologue. However, the lectotype chosen here is the only one which bears Fée’s original label with the species name written by Fée. This sheet has three plants with rhizomes (two on the upper part of the sheet and one more depauperate plant in the middle of the lower part; there are also five leaves distributed around the sheet). The specimen housed at C has only collector’s name and number (similar to many other cases throughout this paper), however, in this occasion, the label has different handwriting style of that from the lectotype and/or other collections (isolectoypes), making it difficult to assure that this specimen is part of the same gathering. Therefore, it has been considered as possible isolectotype.
description: Published as part of Yesilyurt, Jovita Cislinski, 2018, Typifications of thirty-three names and other nomenclatural clarifications referred to Doryopteris and Lytoneuron (Pteridaceae), pp. 138-149 in Phytotaxa 376 (3) on page 144, DOI: 10.11646/phytotaxa.376.3.3, http://zenodo.org/record/13727657
Immunity and Community: Being Stuck and Getting Moving
Creators: name: Bowker, Geoffrey C.
Publisher: name: Tecnoscienza – Italian Journal of Science & Technology Studies
Year: 2020

description: The text contributes to the special issue celebrating the 10th anniversary of the journal Tecnoscienza by presenting a reflection departing from viruses, biology and relationships.
description: Tecnoscienza – Italian Journal of Science & Technology Studies, Vol. 11 No. 1 (2020): Tecnoscienza Nr. 21 – Anniversary Issue
Building a Strategic Plan for your Research Computing and Data Program
Creators: name: Schmitz, Patrick
name: Mizumoto, Claire
name: Brunson, Dana
name: Jennewein, Doug
name: Strachan, Scotty
Publisher: name: Zenodo
Year: 2021
Subjects: Research Computing and Data
Research IT
Strategic Planning
RCD Capabilities Model

description: This workshop will gather Research Computing and Data (RCD) professionals to learn leading practices for developing effective strategic plans for their Research Computing and Data programs. The workshop is open to RCD professionals who are familiar with issues around supporting Research Computing and Data, have experience contributing to strategic planning, and have some exposure to the RCD Capabilities Model. Attendees will hear the experiences of universities (Arizona State University, University of Nevada, Reno, University of Hawaii, plus one more) who are currently using the RCD Capabilities Model as part of their strategic planning work, including lessons learned. Attendees will discuss the range of RCD strategic planning models across the community, and approaches to building a strong strategic planning practice. Finally, participants will define requirements for a new effort to develop a shared community resource to support strategic planning for RCD, identifying potential elements of such a resource and a near-term roadmap for development. Workshop organizers will document the findings of the workshop in a report shared with the community.
description: This workshop was held at PEARC 21
Nothopegia beddomei Gamble 1918
Creators: name: Deepu, S.
name: Geethakumary, M. P.
name: Pandurangan, A. G.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Sapindales
Anacardiaceae
Nothopegia
Nothopegia beddomei

description: 2. Nothopegia beddomei Gamble (1918: 265)
 Type citation:— “ W. Ghats in the Nilgiri, Coimbatore, Anamalai, Pulney and Tinnevelly Hills, up to 5,000 ft. ”
 Type:— INDIA. Tamil Nadu: Tirunelveli District (Tinnevelly), Tinnevelly hills, s.d., Beddome s.n. (lectotype K 000695611!, designated by Matthew (1991: 543))
 Other original material: — INDIA. Tamil Nadu: Nilgiri District (Nilgiris), Kalhatty, June 1884, M. A. Lawson s.n. (MH 00001974!), Gudallur, May 1888, M. A. Lawson s.n. (MH 00001975!).
 Notes:— This species was described by Gamble based on the collections from Nilgiri, Coimbatore, Anamalai, Pulney and Tinnevelly hills. Three herbarium sheets of N. beddomei were traced (K000695611!, MH00001974!, MH00001975!), all containing drawings and determination by J. S. Gamble. In this case, no specimens are actually cited in the protologue, so there are no syntypes. Only localities are cited, so the specimens traced are uncited specimens, which under Art. 9.12 have equal precedence to cited or uncited illustrations when choosing a lectotype. Matthew’s statement “ N. beddomei Gamble, l.c. Type: Beddome s.n. 12/79 Tinnevelly (K)” should be considered as effective lectotypification effective as long as it refers to a specimen that is original material for the name (see Art. 9.4(a)—the protologue mentions only localities, no gatherings/ specimens, i.e. syntypes, are cited; cf. Art. 40 Note 2).
description: Published as part of Deepu, S., Geethakumary, M. P. & Pandurangan, A. G., 2018, Studies Of The Types Of Various Names In The Genus Nothopegia Blume (Anacardiaceae), pp. 150-153 in Phytotaxa 376 (3) on pages 150-151, DOI: 10.11646/phytotaxa.376.3.4, http://zenodo.org/record/13727681
Radio Afterglow Rebrightening: Evidence for Multiple Active Phases in Gamma-Ray Burst Central Engines
Creators: name: Li, L. B.
name: Zhang, Z. B.
name: Rice, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The rebrightening phenomenon is an interesting feature in some X-ray, optical, and radio afterglows of gamma-ray bursts (GRBs). Here, we propose a possible energy-supply assumption to explain the rebrightenings of radio afterglows, in which the central engine with multiple active phases can supply at least two GRB pulses in a typical GRB duration time. Considering the case of double pulses supplied by the central engine, the double pulses have separate physical parameters, except for the number density of the surrounding interstellar medium (ISM). Their independent radio afterglows are integrated by the ground detectors to form the rebrightening phenomenon. In this work, we firstly simulate diverse rebrightening light curves under consideration of different and independent physical parameters. Using this assumption, we also give our best fit to the radio afterglow of GRB 970508 at three frequencies of 1.43, 4.86, and 8.46 GHz. We suggest that the central engine may be active continuously at a timescale longer than that of a typical GRB duration time as many authors have suggested, and that it may supply enough energy to cause the long-lasting rebrightenings observed in some GRB afterglows.
description: 6 pages, 2 figures and 1 table; Comments are welcome
“The Swerve”: A Modest Hint for Appreciating Tradition and Escaping Self-referentiality
Creators: name: Neresini, Federico
Publisher: name: Tecnoscienza – Italian Journal of Science & Technology Studies
Year: 2020

description: The essay suggests “the swerve” as an analytical metaphor useful for researchers and theorists engaged in building the future of STS studies. What is suggested is to shape one's own “swerving methodology”, presented as a “reflective practice” adopted in the comparison with objects, with research questions and STS epistemologies.
description: Tecnoscienza – Italian Journal of Science & Technology Studies, Vol. 11 No. 1 (2020): Tecnoscienza Nr. 21 – Anniversary Issue
การประเมินโครงการเรียนฟรี 15 ปีอย่างมีคุณภาพของสถานศึกษาเอกชน จังหวัดกำแพงเพชร
Creators: name: ธัญญ์กนก ผดุงทรง
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2022
Subjects: การประเมินโครงการ
โครงการเรียนฟรี 15 ปีอย่างมีคุณภาพ
สถานศึกษาเอกชนจังหวัดกำแพงเพชร

description: The Journal of Research and Academics, 5, 6, 37-48
Endozoicomonas euniceicola strain:EF212 Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2012
Subjects: genome sequencing
Monoisolate

description: The goal of this project is to determine the biosynthetic potential of this strain of Endozoicomonas isolated from a Floridian octocoral, Eunicea fusca.
การศึกษาสภาพและแนวทางทางการบริหารการจัดการเรียนรู้ตามหลักสูตรการศึกษาปฐมวัย พุทธศักราช 2560 ในสถานศึกษาสังกัดสำนักงานเขตพื้นที่การศึกษาประถมศึกษาพิษณุโลก เขต 1
Creators: name: ศุภนิดา อินทร์สุข
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2022
Subjects: หลักสูตรการศึกษาปฐมวัย
ปฐมวัย
การจัดการเรียนรู้

description: The Journal of Research and Academics, 5, 6, 49-62
LIGHT induces distinct signals to clear an AAVexpressed persistent antigen in the mouse liver and to induce liver inflammation
Creators: name: Su, Lishan
name: Kovalev, Grigoriy I.
name: Washburn, Michael
name: Fu, Yang-Xin
name: Koroleva, Ekaterina
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Background: Infection with adeno-associated virus (AAV) vector with liver tropism leads to persistent expression of foreign antigens in the mouse liver, with no significant liver inflammation or pathology. This provides a model to investigate antigen persistence in the liver and strategies to modulate host immunity to reduce or clear the foreign antigen expressed from AAV vector in the liver. Methods/Principal Findings: We showed that expressing LIGHT with an adenovirus vector (Ad) in mice with established AAV in the liver led to clearance of the AAV. Ad-LIGHT enhanced CD8 effector T cells in the liver, correlated with liver inflammation. LTbR-Ig proteins blocked Ad-LIGHT in clearing AAV. Interestingly, in LTbR-null mice, Ad-LIGHT still cleared AAV but caused no significant liver inflammation. Conclusions/Significance: Our data suggest that LIGHT interaction with the LTbR plays a critical role in liver inflammation but is not required for LIGHT-mediated AAV clearance. These findings will shed light on developing novel immunotherapeutics in treating people chronically infected with hepato-tropic viruses.
Future Hybrids in an Unsewn World
Creators: name: Mongili, Alessandro
Publisher: name: Tecnoscienza – Italian Journal of Science & Technology Studies
Year: 2020

description: The contribution aims to outline the next steps of STS studies in order to challenge contingencies and changes in an unstable World. The crisis of One-World World’s approach and the appearance of multiplicity in different forms opened up the possibility to a more engaged STS. In this regard, a more lateral approach and a constant attention to unstabilized phenomena has to be promoted.
description: Tecnoscienza – Italian Journal of Science & Technology Studies, Vol. 11 No. 1 (2020): Tecnoscienza Nr. 21 – Anniversary Issue
The “Past Future”. Twenty Years of STS and Technical Universities
Creators: name: Volonté, Paolo
Publisher: name: Tecnoscienza – Italian Journal of Science & Technology Studies
Year: 2020

description: If the public engagement of science and technology has been quickly expanding in the past few decades, the same cannot be said about the presence of STS expertise in the knowledge of scientists, engineers and designers. This article focuses on the opportunity given to STS by the recent trend of European technical universities towards integrating critical and reflexive skills into their educational core.
description: Tecnoscienza – Italian Journal of Science & Technology Studies, Vol. 11 No. 1 (2020): Tecnoscienza Nr. 21 – Anniversary Issue
Auxenochlorella protothecoides strain:0710 Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2014
Subjects: Genome sequencing and assembly
Monoisolate

description: Chlorella protothecoides (Trebouxiophyceae, Chlorophyta) is a genus of single-cell green algae, which was first described by Krüger in 1894. Now, it is highly regarded as one of the potential microalgae for biofuel production due to its ability to accumulate large quantity of lipids within the cell. C. protothecoides is a 2-10 mm in diameter, coccoid and free-living green alga. It contains multiple mitochondria, a single cup-shaped chloroplast, rigid cell wall and no flagella. Unlike most autotrophic green algae, C. protothecoides can not only live autotrophically by fixing sun’s energy through photosynthesis, but also can utilize organic components directly from environment for a heterotrophic growth. Compared with autotrophic cells, the intracellular structure and composition have undergone great changes in the heterotrophic cells. The most attractive phenomenon is the degradation of chloroplast and the accumulation of the oil bodies. The heterotrophic cells are more suitable for biodiesel production due to the increase in both biomass yield (51.2 g/L) and oil content (55.2%). Thus, C. protothecoides can serve as a model to study the mechanism of high oil accumulation and find ways to further reduce the cost of biodiesel.
บทบาทการบริหารกิจการคณะสงฆ์ของพระสังฆาธิการในเขตปกครองคณะสงฆ์อำเภอเมืองสระบุรี จังหวัดสระบุรี
Creators: name: เสาวรถย์ ดีล้วน
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2022
Subjects: บทบาทการบริหาร
การบริหารกิจการคณะสงฆ์
พระสังฆาธิการ

description: The Journal of Research and Academics, 5, 6, 63-74
Cluster automorphism groups of cluster algebras of finite type
Creators: name: Chang, Wen
name: Zhu, Bin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics

description: We study the cluster automorphism group $Aut(\mathcal{A})$ of a coefficient free cluster algebra $\mathcal{A}$ of finite type. A cluster automorphism of $\mathcal{A}$ is a permutation of the cluster variable set $\mathscr{X}$ that is compatible with cluster mutations. We show that, on the one hand, by the well-known correspondence between $\mathscr{X}$ and the almost positive root system $Φ_{\geq -1}$ of the corresponding Dynkin type, the piecewise-linear transformations $τ_+$ and $τ_-$ on $Φ_{\geq -1}$ induce cluster automorphisms $f_+$ and $f_-$ of $\mathcal{A}$ respectively; on the other hand, excepting type $D_{2n},(n\geqslant 2)$, all the cluster automorphisms of $\mathcal{A}$ are compositions of $f_+$ and $f_-$. For a cluster algebra of type $D_{2n},(n\geqslant 2)$, there exists exceptional cluster automorphism induced by a permutation of negative simple roots in $Φ_{\geq -1}$, which is not a composition of $τ_+$ and $τ_-$. By using these results and folding a simply laced cluster algebra, we compute the cluster automorphism group for a non-simply laced finite type cluster algebra. As an application, we show that $Aut(\mathcal{A})$ is isomorphic to the cluster automorphism group of the $FZ$-universal cluster algebra of $\mathcal{A}$.
description: 24 pages, 2 figures in Journal of Algebra 2015
The CATERPILLER protein Monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor α-, and Mycobacterium tuberculosis-induced pro-inflammatory signals
Creators: name: Vogel, Stefanie N.
name: Accavitti-Loper, Mary A.
name: Su, Lishan
name: Braunstein, Miriam
name: Williams, Kristi L.
name: Rallabhandi, Prasad
name: Lich, John D.
name: Moore, Christopher
name: Coffield, V. McNeil
name: Duncan, Joseph A.
name: Ting, Jenny P.-Y.
name: Kurtz, Sherry
name: Reed, William
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: The CATERPILLER (CLR, also NOD and NLR) proteins share structural similarities with the nucleotide binding domain (NBD)-leucine-rich repeat (LRR) superfamily of plant disease-resistance (R) proteins and are emerging as important immune regulators in animals. CLR proteins contain NBD-LRR motifs and are linked to a limited number of distinct N-terminal domains including transactivation, CARD (caspase activation and recruitment), and pyrin domains (PyD). The CLR gene, Monarch-1/Pypaf7, is expressed by resting primary myeloid/monocytic cells, and its expression in these cells is reduced by Toll-like receptor (TLR) agonists tumor necrosis factor (TNF) α and Mycobacterium tuberculosis. Monarch-1 reduces NFκB activation by TLR-signaling molecules MyD88, IRAK-1 (type I interleukin-1 receptor-associated protein kinase), and TRAF6 (TNF receptor (TNFR)-associated factor) as well as TNFR signaling molecules TRAF2 and RIP1 but not the downstream NFκB subunit p65. This indicates that Monarch-1 is a negative regulator of both TLR and TNFR pathways. Reducing Monarch-1 expression with small interference RNA in myeloid/monocytic cells caused a dramatic increase in NFκB activation and cytokine expression in response to TLR2/TLR4 agonists, TNFα, or M. tuberculosis infection, suggesting that Monarch-1 is a negative regulator of inflammation. Because Monarch-1 is the first CLR protein that interferes with both TLR2 and TLR4 activation, the mechanism of this interference is significant. We find that Monarch-1 associates with IRAK-1 but not MyD88, resulting in the blockage of IRAK-1 hyperphosphorylation. Mutants containing the NBD-LRR or PyD-NBD also blocked IRAK-1 activation. This is the first example of a CLR protein that antagonizes inflammatory responses initiated by TLR agonists via interference with IRAK-1 activation.
Building and Selling a Strategic Plan for your Research Computing and Data Program
Creators: name: Schmitz, Patrick
name: Mizumoto, Claire
name: Brunson, Dana
name: Jennewein, Doug
name: Collier, Galen
name: Hicks, John
Publisher: name: Zenodo
Year: 2022
Subjects: Research Computing and Data
Research IT
Strategic Planning
RCD Capabilities Model

description: This workshop will bring together Research Computing and Data professionals to explore a formal framework for strategic planning, how to identify the stakeholders crucial to realizing a strategic plan, and successful approaches to winning support among these stakeholders. The workshop will foster the establishment of peer mentoring relationships, and an active practice of leveraging these relationships to share leading practices around strategic planning. The workshop is open to RCD professionals who are familiar with issues around supporting Research Computing and Data, have experience contributing to strategic planning, and have some exposure to the RCD Capabilities Model.
description: This workshop was held at PEARC22 in Boston
Constraints on the Minor Merging and Star Formation History of the Wolf-Rayet Galaxy NGC 5430 Through Observations
Creators: name: Pan, Hsi-An
name: Kuno, Nario
name: Sorai, Kazuo
name: Umei, Michiko
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We used multi-wavelength analysis of the newly observed molecular gas (12CO and 13CO (1-0)) with interferometer CARMA and archival star formation tracers to constrain the interaction, merging, and star formation history of an off-center minor merger, a three-spiral barred galaxy NGC 5430 and its satellite embedded in the bar. Morphology of the molecular gas in the bar of NGC 5430 shows minimal signs of recent interactions in our resolution. The apparent morphological remnant of the past galaxy interaction is an asymmetric spiral arm, containing more molecular gas and exhibiting higher star formation rate (SFR) surface density than the two primary arms. Rotation curve analysis suggests that NGC 5430 and its satellite collided several Gyr ago. History of star formation was constrained by using SFRs that trace different timescales (infrared, radio continuum, and H-alpha). The collision occurred 5 - 10 Myr ago, triggering a transient off-center starburst of Wolf-Rayet stars at the eastern bar end. In the past, the global SFR during the Wolf-Rayet starburst peaked at 35 Msun/yr. At present, the merger-driven starburst is rapidly decaying and the current global SFR has decreased to the Galactic value. The SFR will continue to decay as suggested by the present amount of dense gas (traced by HCN (1-0)). Nonetheless, the global SFR is still dominated by the Wolf-Rayet region rather than the circumnuclear region. Compared with other barred galaxies, the circumnuclear region exhibits particularly low dense gas fraction, low star formation activity and high concentration of gas. Physical properties of the molecular gas are inferred by using the large velocity gradient (LVG) calculations. The initial mass ratio of the NGC 5430 and its satellite are suggested to be in the intermediate ratio range of 7:1-20:1.
description: 16 pages, 9 figures, accepted for publication in PASJ
Sterile Neutrino Dark Matter Production in the Neutrino-phillic Two Higgs Doublet Model
Creators: name: Adulpravitchai, Adisorn
name: Schmidt, Michael A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Sterile Neutrinos with a mass in the keV range form a good candidate for dark matter. They are naturally produced from neutrino oscillations via their mixing with the active neutrinos. However the production via non-resonant neutrino oscillations has recently been ruled out. The alternative production via Higgs decay is negligibly small compared to neutrino oscillations. We show that in the neutrino-phillic two Higgs doublet model, the contribution from Higgs decay can dominate over the contribution from neutrino oscillations and evade all constraints. We also study the free-streaming horizon and find that a sterile neutrino mass in the range of 4 to 53 keV leads to warm dark matter.
description: 20 pages, 3 figures; v2: references added, Pauli blocking included, leading to about 40% correction to DM abundance, freestreaming horizon unaffected, conclusions unchanged, published in JHEP
การพัฒนารูปแบบการประกันคุณภาพภายในสถานศึกษาของผู้บริหารโรงเรียนมัธยมศึกษาในสังกัดสำนักงานเขตพื้นที่การศึกษามัธยมศึกษานครสวรรค์ตามหลักทุติยปาปณิกสูตร
Creators: name: นิรมล รอดไพ
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2022
Subjects: ผู้บริหาร
รูปแบบการประกันคุณภาพภายในสถานศึกษา
หลักทุติยปาปณิกสูตร

description: The Journal of Research and Academics, 5, 6, 75-86
Gatekeeper training for vendors to reduce pesticide self-poisoning in rural South Asia
Creators: name: Metcalfe, Chris
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Medicine and Health Sciences
subject: Cluster randomized trial
subject: Gatekeeper
subject: South Asia
subject: Sri Lanka
subject: Stepped wedge
subject: pesticides
subject: self-poisoning

description: The statistical analysis plan (SAP) for this study was written and uploaded here before the study data were available for analysis. The plan is freely available here.
Deep Sequencing identifies regulated small RNAs in Dugesia japonica
Creators: name: BGI
Publisher: name: CNGB
Year: 2012
Subjects: Transcriptome or Gene expression
Multiisolate

description: We applied Illumina sequencing to identify microRNAs (miRNAs) and piwi-interacting small RNAs (piRNAs) in Dugesia japonica. Dugesia were cut up after seven day’s starvation. DJ1 is the whole Dugesia body, DJ2 is the head part, DJ3 is the tail part, DJ4 is the left part and DJ5 is the right part. Total RNA was extracted by Trizol, and preserved in ethanol, stored at -80°C until further use.Overall design: 5 samples examined：DJ1,DJ2,DJ3,DJ4,DJ5.SRA study (not submitted by GEO): SRP017693
Donaldson-Thomas theory of $[\mathbb{C}^2/\mathbb{Z}_{n+1}]\times \mathbb{P}^1$
Creators: name: Zhou, Zijun
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We study the relative orbifold Donaldson-Thomas theory of $[\mathbb{C}^2/\mathbb{Z}_{n+1}]\times \mathbb{P}^1$. We establish a correspondence between the DT theory relative to 3 fibers to quantum multiplication by divisors in the Hilbert scheme of points on $[\mathbb{C}^2/\mathbb{Z}_{n+1}]$. This determines the whole theory if a further nondegeneracy condition is assumed. The result can also be viewed as a crepant resolution correspondence to the DT theory of $\mathcal{A}_n\times \mathbb{P}^1$.
description: 44 pages, 1 figure. Minor changes, Selecta Mathematica New Series (2018)
Nothopegia racemosa var. angustifolia Chitra 1983
Creators: name: Deepu, S.
name: Geethakumary, M. P.
name: Pandurangan, A. G.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Sapindales
Anacardiaceae
Nothopegia
Nothopegia racemosa
Nothopegia racemosa var. angustifolia (gamble 1918: 265) chitra (1983: 88)

description: 4. Nothopegia racemosa var. angustifolia (Gamble 1918: 265) Chitra (1983: 88)
 Nothopegia dalzellii var. angustifolia Gamble (1918: 265) (nom. superfl.)
 Type citation:— “Nilgiri and Pulney Hills (Bourne)”
 Type:— INDIA. Tamil Nadu: Nilgiri District, Coonoor, 02 July 1896, Bourne s.n. (lectotype K 000695600!, designated by Matthew (1991: 543))
 Syntype: — INDIA. Tamil Nadu: Dindigul District, Perumbukanal—Pulneys, 07 December 1898, Bourne 859 (MH 00001972!).
 Notes:— N. dalzelli var. angustifolia was described by Gamble (1918) based on the collections of Bourne. Since the species name was superfluous, Chitra (1983) published the new combination N. racemosa var. angustifolia. We were able to trace two sheets of Bourne at K (K 000695600!) and MH (MH 00001972!) and both the sheets contain the determination and drawings by Gamble. Matthew (1991) in his precursory notes for the Flora of Pulney hills had noted “ var. angustifolia Gamble, 1.c. Type: A. G. Bourne s.n. Connoor (K)”. This should be treated as an effective lectotypification. As per Art. 7.3., Nothopegia racemosa var angustifolia (Gamble) Chitra is automatically typified by the type of its basionym.
description: Published as part of Deepu, S., Geethakumary, M. P. & Pandurangan, A. G., 2018, Studies Of The Types Of Various Names In The Genus Nothopegia Blume (Anacardiaceae), pp. 150-153 in Phytotaxa 376 (3) on page 151, DOI: 10.11646/phytotaxa.376.3.4, http://zenodo.org/record/13727681
การพัฒนาสมรรถนะครูในช่วงยุทธศาสตร์ชาติ (พ.ศ.2561-2580)
Creators: name: ฐกร พฤฒิปูรณี
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2022
Subjects: สมรรถนะ
ยุทธศาสตร์ชาติ
การพัฒนาครู

description: The Journal of Research and Academics, 5, 6, 87-98
Gα13 mediates a signal that is essential for proliferation and survival of thymocyte progenitors
Creators: name: Su, Lishan
name: Coffield, V. McNeil
name: Helms, Whitney S.
name: Jiang, Qi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: G protein signaling via the Gα12 family (Gα12 and Gα13) has not been well studied in T cells. To investigate whether Gα12 and Gα13 are involved in thymopoiesis, we expressed the regulator of G protein signaling domain of p115RhoGEF to inhibit Gα12 and Gα13 during thymopoiesis. Fetal thymus organ cultures seeded with p115ΔDH-expressing progenitor cells showed impaired thymopoiesis with a block at the CD4 -CD8-CD44-CD25+ (DN3) stage. Using Gα13 or Gα12 minigenes, we demonstrated that Gα13, but not Gα12, is required for thymopoiesis. T progenitor cells expressing p115ΔDH showed reduced proliferation and increased cell death. T cell receptor stimulation of the fetal thymus organ cultures did not rescue the block. Overexpression of the antiapoptotic gene Bcl2 rescued the defect in DN3 cells and partially rescued T cell development. Therefore, Gα13-mediated signaling is necessary in early thymocyte proliferation and survival.
Formation of Bright Solitons from Wave Packets with Repulsive Nonlinearity
Creators: name: Wang, Zihui
name: Cherkasskii, Mikhail
name: Kalinikos, Boris A.
name: Carr, Lincoln D.
name: Wu, Mingzhong
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: Formation of bright envelope solitons from wave packets with a repulsive nonlinearity was observed for the first time. The experiments used surface spin-wave packets in magnetic yttrium iron garnet (YIG) thin film strips. When the wave packets are narrow and have low power, they undergo self-broadening during the propagation. When the wave packets are relatively wide or their power is relatively high, they can experience self-narrowing or even evolve into bright solitons. The experimental results were reproduced by numerical simulations based on a modified nonlinear Schrödinger equation model.
description: 10 pages, 4 figures
The Role of Brg1, a Catalytic Subunit of Mammalian Chromatin-remodeling Complexes, in T Cell Development
Creators: name: Godfrey, Virginia
name: Geburhr, Thomas C.
name: Bultman, Scott
name: Manguson, Terry
name: Su, Lishan
name: Kovalev, Grigoriy I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: Mammalian SWI-SNF-related complexes use brahma-related gene 1 (Brg1) as a catalytic subunit to remodel nucleosomes and regulate transcription. Recent biochemical data has linked Brg1 function to genes important for T lymphocyte differentiation. To investigate the role of SWI-SNF-related complexes in this lineage, we ablated Brg1 function in T lymphocytes. T cell-specific Brg1-deficient mice showed profound thymic abnormalities, CD4 depression at the double negative (DN; CD4- CD8-) stage, and a developmental block at the DN to double positive (CD4+ CD8 +) transition. 5′-bromo-2′-deoxyuridine incorporation and annexin V staining establish a role for Brg1 complexes in the regulation of thymocyte cell proliferation and survival. This Brg1-dependent cell survival is specific for developing thymocytes as indicated by the presence of Brg1-deficient mature T lymphocytes that have escaped the developmental block in the thymus. However, reductions in peripheral T cell populations lead to immunodeficiency and compromised health of mutant mice. These results highlight the importance of chromatin-remodeling complexes at different stages in the development of a mammalian cell lineage.
แรงจูงใจที่ส่งผลต่อประสิทธิภาพในการปฏิบัติงานของฝ่ายปกครองอำเภอท่าวุ้ง จังหวัดลพบุรี
Creators: name: นิลวรรณ บุญสันต์
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2022
Subjects: แรงจูงใจในการปฏิบัติงาน
ประสิทธิภาพในการปฏิบัติงาน
ฝ่ายปกครอง

description: The Journal of Research and Academics, 5, 6, 99-110
Resolution Dependence of Disruptive Collisions between Planetesimals in the Gravity Regime
Creators: name: Genda, H.
name: Fujita, T.
name: Kobayashi, H.
name: Tanaka, H.
name: Abe, Y.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Collisions are a fundamental process in planet formation. If colliding objects simply merge, a planetary object can grow. However, if the collision is disruptive, planetary growth is prevented. Therefore, the impact conditions under which collisions are destructive are important in understanding planet formation. So far, the critical specific impact energy for a disruptive collision Q_D^* has been investigated for various types of collisions between objects ranging in scale from centimeters to thousands of kilometers. Although the values of Q_D^* have been calculated numerically while taking into consideration various physical properties such as self-gravity, material strength, and porosity, the dependence of Q_D^* on numerical resolution has not been sufficiently investigated. In this paper, using the smoothed particle hydrodynamics (SPH) method, we performed numerical simulations of collisions between planetesimals at various numerical resolutions (from 2 x 10^4 to 5 x 10^6 SPH particles) and investigated the resulting variation in Q_D^*. The value of Q_D^* is shown to decrease as the number of SPH particles increases, and the difference between the Q_D^* values for the lowest and highest investigated resolutions is approximately a factor of two. Although the results for 5 x 10^6 SPH particles do not fully converge, higher-resolution simulations near the impact site show that the value of Q_D^* for the case with 5 x 10^6 SPH particles is close to the expected converged value. Although Q_D^* depends on impact parameters and material parameters, our results indicate that at least 5 x 10^6 SPH particles are required for numerical simulations in disruptive collisions to obtain the value of Q_D^* within 20% error.
description: Accepted for publication in Icarus, 29 pages, 11 figures
การตัดสินใจสมัครเข้าร่วมเป็นผู้ประกันตน มาตรา 40 ของแรงงานนอกระบบ กรณีศึกษาสำนักงานประกันสังคมจังหวัดสระบุรี สาขาหนองแค
Creators: name: อสมาภรณ์ กล่อมจิตร์
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2022
Subjects: การตัดสินใจ
ผู้ประกันตนมาตรา 40
แรงงานนอกระบบ

description: The Journal of Research and Academics, 5, 6, 111-122
What Can We Learn from the History of STS in Italy? A Few Hints for the Future
Creators: name: Pancaldi, Giuliano
Publisher: name: Tecnoscienza – Italian Journal of Science & Technology Studies
Year: 2020

description: By recalling his own career as an historian of science and technology, the author sketches the history of Science and Technology Studies in Italy from their early steps in the 1970s and 1980s. He highlights the ways in which the field has gained visibility and substance in the Italian context, but also pointing out the constraints and hurdles that still must be overcome to consolidate it. In particular, the author underlines how the traditionally rigid disciplinary partitions of Italian academia and the nationally centralized system of Italian universities have hindered, and still hinder, the institutionalization and the potential impact of STS south of the Alps.
description: Tecnoscienza – Italian Journal of Science & Technology Studies, Vol. 11 No. 1 (2020): Tecnoscienza Nr. 21 – Anniversary Issue
รูปแบบการบริหารสถานศึกษาเพื่อพัฒนาสมรรถนะของผู้เรียนระดับมัธยมศึกษาในศตวรรษที่ 21 ตามหลักอิทธิบาท 4
Creators: name: รวิวรรณ สุ่มมาตย์
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2022
Subjects: รูปแบบการบริหารสถานศึกษา
สมรรถนะผู้เรียนในศตวรรษที่ 21
หลักอิทธิบาท 4

description: The Journal of Research and Academics, 5, 6, 123-136
Cicer arietinum cultivar:CDC Frontier RefSeq Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2012
Subjects: RefSeq genome sequencing
Monoisolate

description: The whole genome shotgun (wgs) draft of the chickpea genome is based on genotype CDC Frontier, a Canadian kabuli chickpea variety. The availability of these genome sequences is important for crop improvement of chickpea, and should help to advance genomic research of chickpea and other legume crops.