cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Statistical aspects of the allocation of patients for remote patient management via biomarker criteria: a simulation study
Creators: name: Pigorsch, Mareen
name: Möckel, Martin
name: Gehrig, Stefan
name: Wiemer, Jan C.
name: Köhler, Friedrich
name: Rauch, Geraldine
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: telemedicine
subject: biomarker
subject: simulation
subject: 610 Medical sciences; Medicine

description: Remote patient management (RPM) can be useful to observe early signs of upcoming medical events and enable appropriate care thereby ideally preventing unfavorable events. While low-risk patients are unlikely to benefit from RPM, the telemedicine-intervention is likely to be most useful for high-risk[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Stau-catalyzed $^6$Li Production in Big-Bang Nucleosynthesis
Creators: name: Hamaguchi, K.
name: Hatsuda, T.
name: Kamimura, M.
name: Kino, Y.
name: Yanagida, T. T.
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: If the gravitino mass is in the region from a few GeV to a few 10's GeV, the scalar lepton X such as stau is most likely the next lightest supersymmetry particle. The negatively charged and long-lived X^- may form a Coulomb bound state (A X) with a nucleus A and may affect the big-bang nucleosynthesis through catalyzed fusion process. We calculate a production cross section of Li6 from the catalyzed fusion (He4 X^-) + d \to Li6 + X^- by solving the Schrödinger equation exactly for three-body system of He4, d, and X. We utilize the state-of-the-art coupled-channel method, which is known to be very accurate to describe other three-body systems in nuclear and atomic reactions. The importance of the use of appropriate nuclear potential and the exact treatment of the quantum tunneling in the fusion process are emphasized. We find that the astrophysical S-factor at the Gamow peak corresponding to T=10 keV is 0.038 MeV barn. This leads to the Li6 abundance from the catalyzed process as Li6|_{CBBN}\simeq 4.3\times 10^{-11} (D/2.8\times 10^{-5}) ([n_{X^-}/s]/10^{-16}) in the limit of long lifetime of X. Particle physics implication of this result is also discussed.
description: 16 pages, 7 figures
Πράσινες γέφυρες εντός αστικού και περιαστικού τοπίου: Πρόταση δημιουργίας πράσινης γέφυρας στον περιφερειακό του Δήμου Ευόσμου Θεσσαλονίκης:
Creators: name: Μαρκόπουλος, Χρήστος Κυριάκου
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Πράσινες γέφυρες
Πράσινα περάσματα άγριας ζωής
Εύοσμος
Περιφερειακός δρόμος
Green bridge
Wildlife Overpass
Evosmos
Ring road

description: Σκοπός της συγκεκριμένης διπλωματικής διατριβής είναι η ανάδειξη τρόπων αντιμετώπισης των προβλημάτων που δημιουργούν οι κεντρικές οδικές αρτηρίες, όπως οι περιφερειακοί οδοί μεγάλων πόλεων και οι οδικοί άξονες, όπως αυτοκινητόδρομοι, οι οποίοι τεμαχίζουν εκτάσεις και περιοχές αστικού και περιαστικού τοπίου. Στο πρώτο σκέλος της διπλωματικής παρουσιάζονται παραδείγματα εφαρμογής λύσεων από την Ελλάδα και το εξωτερικό, το ρόλο του αρχιτέκτονα τοπίου στην προσπάθεια της αποκατάστασης της σύνδεσης των περιοχών αυτών, όπως και των προβλημάτων που προσπαθεί να λύσει στην κάθε ξεχωριστή περίπτωση που συναντά. Στο δεύτερο σκέλος της διπλωματικής, προτείνεται η κατασκευή πράσινης γεφύρας στο δυτικό τμήμα της εσωτερικής περιφερειακής, στο ύψος του δήμου Εύοσμου. Επίσης, προτείνονται καινοτόμες εφαρμογές που συμβάλουν περαιτέρω στην οικολογική λειτουργικότητα της γέφυρας όπως ενεργειακή και υδατική αυτονομία του έργου, χρήση του φυσικού φωτισμού για τη φωταγώγηση της σήραγγας, αξιοποίηση των τοπικών ανέμων (Βαρδάρης), χρήση ανακυκλώσιμων υλικών στις υποδομές του πάρκου, πράσινα ηχοπετάσματα, στοχευμένες φυτεύσεις κ.α.
description: The aim of this thesis is to highlight ways to address the problems posed by key roads such as major cities' ring roads and arterial routes such as highways, which parcel areas of the urban and suburban landscape.In the first part of the thesis we present examples of solutions implemented in Greece and abroad, the role of landscape architect in his effort to restore connection of such areas, and solve the problems they encounter in each case.In the second part of the thesis we propose construction of a "green bridge" in the Western part of the inner ring road, at the height of municipality of Evosmos. Additionally, we propose innovative applications that further contribute to the ecological functionality of this bridge such as: energy and water autonomous project, use of natural daylight to illuminate the tunnel, use of local winds (Vardaris-strong North wind), use of recycled materials in the infrastructure of the park, green noise-barriers, targeted plantings etc.
title: Biomarker selection in a federated setting with data protection constraints
Creators: name: Zöller, Daniela
name: Amsel, Daniel
name: Lenz, Stefan
name: Fischer, Patrick
name: Schneider, Henning
name: Dohmen, Hildegard
name: Acker, Till
name: Binder, Harald
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: federated analysis
subject: boosting
subject: data protection constraints
subject: multivariable prognostic score
subject: DataSHIELD
subject: 610 Medical sciences; Medicine

description: Background: Genetic biomarkers become increasingly more important for clinical management of patients, but the discovery of new ones requires large cohorts. In many countries, data protection constraints forbid exchange of individual-level data between different research institutes, but researchers [for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Two hard spheres in a spherical pore: Exact analytic results in two and three dimensions
Creators: name: Urrutia, Ignacio
Publisher: name: arXiv
Year: 2006
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The partition function and the one- and two-body distribution functions are evaluated for two hard spheres with different sizes constrained into a spherical pore. The equivalent problem for hard disks is addressed too. We establish a relation valid for any dimension between these partition functions, second virial coefficient for inhomogeneous systems in a spherical pore, and third virial coefficients for polydisperse hard spheres mixtures. Using the established relation we were able to evaluate the cluster integral $b_{2}(V)$ related with the second virial coefficient for the Hard Disc system into a circular pore. Finally, we analyse the behaviour of the obtained expressions near the maximum density.
description: def printed version
Symmetry and transport property of spin current induced spin-Hall effect
Creators: name: Xing, Yanxia
name: Sun, Qing-feng
name: Wang, Jian
Publisher: name: arXiv
Year: 2007
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the spin current induced spin-Hall effect that a longitudinal spin dependent chemical potential $qV_{s=x,y,z}$ induces a transverse spin conductances $G^{ss'}$. A four terminal system with Rashba and Dresselhaus spin-orbit interaction (SOI) in the scattering region is considered. By using Landauer-B$\ddot u$ttiker formula with the aid of the Green function, various spin current induced spin-Hall conductances $G^{ss'}$ are calculated. With the charge chemical potential $qV_c$ or spin chemical potential $qV_{s=x,y,z}$, there are 16 elements for the transverse conductances $G^{μν}_p=J_{p,μ}/V_ν$ where $μ,ν=x,y,z,c$. Due to the symmetry of our system these elements are not independent. For the system with $C_2$ symmetry half of elements are zero, when the center region only exists the Rashba SOI or Dresselhaus SOI. The numerical results show that of all the conductance elements, the spin current induced spin-Hall conductances $G^{ss'}$ are usually much greater (about one or two orders of magnitude) than the spin Hall conductances $G^{sc}$ and the reciprocal spin Hall conductances $G^{cs}$. So the spin current induced spin-Hall effect is dominating in the present device.
description: 7 pages, 6 figures
title: Trend estimation for crop yield – can we ignore an informative drop-out of data?
Creators: name: Hartung, Jens
name: Piepho, Hans-Peter
name: Laidig, Friedrich
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: informative missing
subject: mixed model
subject: trend estimation
subject: 610 Medical sciences; Medicine

description: Crop yield has increased during the last decades due to genetic gain and improved agronomic practices. In Germany, this trend can be seen in series of official value-of-cultivation-and-use (VCU) trials and on-farm. The genetic gain results from cultivating newly registered and enhanced cultivars selected[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Overview of Non-Relativistic QCD
Creators: name: Soto, Joan
Publisher: name: arXiv
Year: 2006
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: An overview of recent theoretical progress on Non-Relativistic QCD and related effective theories is provided.
description: Plenary talk at the 4th International Conference on Quarks and Nuclear Physics (QNP06), 5-10 June 2006, Madrid, Spain; 6 pages, 1 figure, EPJ style. References added. Journal version
Possibility of mixed helical p-wave pairings in Sr$_2$RuO$_4$
Creators: name: Huang, Wen
name: Wang, Zhiqiang
Publisher: name: arXiv
Year: 2021
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The exact nature of unconventional superconductivity in Sr$_2$RuO$_4$ remains a mystery. At the phenomenological level, no superconducting order parameter proposed thus far seems able to coherently account for all essential experimental signatures. Among the latter is the prominent polar Kerr effect, which implies a nonzero ac anomalous Hall conductivity. Assuming the Kerr effect is intrinsic, it can be accounted for by a bulk chiral Cooper pairing with nonzero orbital angular momentum, such as $p+ip$ or $d+id$, which, however, has difficulties in being reconciled with other experimental results. Given the situation, in this paper, we propose alternative possibilities with complex mixtures of distinct helical p-wave order parameters, namely, $A_{1u}+iA_{2u}$ and $B_{1u}+iB_{2u}$ in the group theory nomenclature. These states essentially consist of two copies of chiral p-wave pairings with opposite chirality and different pairing amplitudes, and therefore support intrinsic Hall and Kerr effects. We further show that these states exhibit salient features that may explain several other key observations in this material, including the absence of spontaneous edge current, a substantial Knight shift drop, and possibly signatures in uniaxial strain and ultrasound measurements.
description: published version; 5 pages, 4 figures + supplemental material
Διαχείριση και Σχεδιασμός Φυσικού Ορεινού Τοπίου για την δημιουργία πάρκου άθλησης και αναψυχής:
Creators: name: Γιουβεζνάλης, Βασίλειος Πασχάλη
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Αρχιτεκτονική Τοπίου
Φυσικό
Διαχείρηση
Landscape
Natural
Management

description: Σκοπός της διατριβής ήταν η μελέτη της διαδικασίας για ορθολογική διαχείριση της μορφής, τη σύνθεση ή / και το μοτίβο των δασών με τρόπους που θα λαμβάνουν υπόψη τις πολλαπλές σκοπούς και στόχους. Στη συνέχεια, παρουσιάσαμε τον τρόπο με τον οποίο τα φυσικά και διαχειριζόμενα ορεινά τοπία αποτελούν χωρικά μοτίβα σε μεγάλες περιοχές. Η φύση, η μορφή και η χωρική κατανομή αυτών των μοτίβων στο χώρο και στο χρόνο μπορεί και πρέπει να είναι συνειδητά σχεδιασμένη. Ενώ είναι διαδεδομένο στο να σκεφτούμε το ορεινά τοπία και κατα προέκταση τα δάση ως «διαχείριση», σπάνια σκεφτόμαστε τις ίδιες περιοχές ‘ως “σχεδιασμένη”. Eτσι μπορούμε να καταλήξουμε στο οτι οι αρχιτέκτονες τοπίου συχνά τροποποιούν την τοπογραφία, την αφαίρεση ή τη φύτευση βλάστησης, προσθέτοντας ή αφαιρώντας το νερό, καθορίζει μονοπάτια και ούτω καθεξής. Με τον τρόπο αυτό, ένας αρχιτέκτονας τοπίου έχει εμπλακεί σε μια μορφή της εφαρμοσμένης οικολογίας, και σχεδιάζει πώς να αλλάξει τα σχέδια του τοπικού οικοσυστήματος για να διευκολυνθεί η προοριζόμενη χρήση του.Ασχοληθήκαμε επιπλέον με την ιστορική διάσταση των παγιωμένων εκφράσεων της νέας ελληνικής και διαπιστώσαμε την παρουσία τους από την αρχαιότητα μέχρι σήμερα.
description: The aim of the present thesis was the study of a process for deliberate management of the form, composition and/or pattern of forests in ways that take account of multiple goals and objectives. Then was presented the way that the natural and managed landscapes form spatial mosaics over large areas. It is the nature, form and distribution of these mosaics over space and time that can and should be consciously designed. While it is common to think of forests as being “managed”, we rarely think of them as being “designed”. So landscape designers frequently involves modifying topography, removing or planting vegetation, adding or removing water, setting out paths and so on. In doing this, a designer is engaged in a form of applied ecology, and is envisaging how to alter the patterns of a local ecosystem to facilitate its intended use.
Heterotic Compactification, An Algorithmic Approach
Creators: name: Anderson, Lara B.
name: He, Yang-Hui
name: Lukas, Andre
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We approach string phenomenology from the perspective of computational algebraic geometry, by providing new and efficient techniques for proving stability and calculating particle spectra in heterotic compactifications. This is done in the context of complete intersection Calabi-Yau manifolds in a single projective space where we classify positive monad bundles. Using a combination of analytic methods and computer algebra we prove stability for all such bundles and compute the complete particle spectrum, including gauge singlets. In particular, we find that the number of anti-generations vanishes for all our bundles and that the spectrum is manifestly moduli-dependent.
description: 36 pages, Latex
Potassium transport in Chlamydomonas reinhardtii
Creators: name: Malhotra, Bhupinder K.
Publisher: name: University of British Columbia
Year: 2009

description: Several lines of evidence have indicated that K⁺ uptake is mediated by both protein carriers and channels according to external [K⁺]. Evidence derived from biophysical, biochemical and molecular studies of K⁺ uptake in higher plants, fungi and bacteria indicate that K⁺ uptake is mediated by proteinaceous carriers (active transport) and channels (passive) depending upon the external concentration of K⁺. Only limited work has been undertaken using microalgae. In Chiamydomonas reinhardtii, K⁺ influx appears to be mediated by two discrete transport systems, a high affinity transport system (HATS) at low external [K⁺] and a low affinity transport system (LATS) at high external [K⁺]. These two transport systems were further characterized by employing various metabolic inhibitors, a K⁺ channel blocker and a sulfhydryl reagent. Effects of light and dark on K⁺ transport were also studied. To calculate Δμk⁺ across the plasma membrane, electrical potential difference (Δψ) was measured using TPP⁺, and cytoplasmic [K⁺] was obtained from compartmental analysis. According to this value of Δμk⁺, K⁺ enters the cell against its electrochemical potential gradient at low [K⁺]₀ (<0.2 mM) and is probably moving down the electrochemical gradient at high [K⁺]₀ (>1 mM). In isolated chloroplasts, [K⁺] was found to be 165±21 mM. This value was close to that estimated by compartmental analysis (223±31.4 mM). Compartmental analysis of cells using ⁸⁶Rb⁺ and ⁴²K⁺ as the tracers also showed the presence of three cellular compartments and their half-lives. Three compartments detected in Chiamydomonas probably correspond to the cell wall, cytoplasm and chioroplast, respectively. Comparisons of compartmental analysis of wild type and trkl cells showed that compartment III (putatively identified as the chioroplast) may serve as a reservoir for K⁺. It is a common observation that plants show increased ion uptake when deprived of nutrients. Chiamydomonas showed increased uptake of K⁺(⁴²K⁺or ⁸⁶Rb⁺) when K⁺ supply decreased in the external medium. Inhibitors of protein synthesis were used to study the role of de novo protein synthesis in the development of increased K influx associated with K⁺ deprivation. There was no significant increase in K⁺ uptake before 3 h of K⁺ deprivation. K⁺ influx increased significantly after 3 h and peaked at about 18 h of K⁺ deprivation. In parallel experiments, expression of membrane polypeptides was studied. Some polypeptides in response to K⁺ deprivation were expressed in the microsomal fraction. When cells were deprived of K⁺ for 4 h, a 22 kD polypeptide showed increased expression. Another polypeptide of Mr 51 kD was synthesised as a response to long term K⁺ deprivation. When comparisons were made between microsomal fractions from WT and trkl cells, a 21 kD polypeptide was found to be absent from trkl microsomes.
title: Pre-specified matching analyses in an observational study to evaluate treatment effects in a rare disease
Creators: name: Herich, Lena
name: Proescholdt, Martin
name: Buchner, Hannes
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: propensity score matching
subject: observational studies
subject: rare disease
subject: 610 Medical sciences; Medicine

description: Background: Matching algorithms, as the propensity score matching, were introduced a long time ago (see eg. Rosenbaum and Rubin [ref:1]). However, they are nowadays not only used in epidemiological research but also more and more in clinical research [ref:2]. Examples range from [for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
title: Visualisation of alternating shielding gas flow in GTAW - Figure data
Creators: name: Bitharas, Ioannis
name: Campbell, Stuart
name: Galloway, Alexander
name: McPherson, Norrie
name: Moore, Andrew J
Publisher: name: Heriot-Watt University
Year: 2015

description: If using this figure data, please cite:
Citation to be updated on publication.
title: Nonparametric Limits of Agreement for small to moderate sample sizes – a simulation study
Creators: name: Frey, Maria Elisabeth
name: Petersen, Hans Christian
name: Gerke, Oke
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: agreement
subject: Bland-Altman analysis
subject: quantile estimation
subject: repeatability
subject: reproducibility
subject: 610 Medical sciences; Medicine

description: Background: The assessment of agreement in method comparison and observer variability analysis of quantitative measurements is usually done by the Bland-Altman Limits of Agreement, where the paired differences are implicitly assumed to follow a normal distribution. Whenever this assumption does not[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Genetic analysis of huntington disease
Creators: name: Andrew, Susan E.
Publisher: name: University of British Columbia
Year: 2009

description: Huntington disease (lID) is an autosomal dominant neurodegenerative disease characterized by progressive dementia and chorea. The initial aim of this thesis was to identify candidate regions for the HD gene. Markers separated by 3 Mb were found to be in strong allelic association with HI), thus identifying two mutually exclusive candidate regions. A screen for genomic rearrangements in affected individuals using exonic clones from the proximal candidate region was undertaken. One auspicious clone showed a genomic rearrangement, cosegregating with HI) in two families. Subsequent cloning and sequencing of this region demonstrated an Alu retrotransposition event associated with Huntington disease in the two families. During this work, the mutation causing Huntington disease was identified by the HD Collaborative Research Group as an expanded CAG trinucleotide repeat in a novel gene. Analysis of new polymorphic markers in the gene permitted a retrospective analysis of linkage disequilibrium in a 300kb region harbouring the CAG repeat. Analysis of HI) haplotypes showed that multiple haplotypes underlie CAG expansion. Mean CÁO length on control chromosomes with haplotypes identical to those most frequently observed in HI) were significantly larger than CAG lengths on other control chromosomes, consistent with the hypothesis that these chromosomes are a reservoir for further expansions, resulting in Hi) chromosomes. The nature of the dynamic trinucleotide repeat mutation resolved several previously confusing issues of HI). There is a highly significant correlation between the age of onset of Huntington disease and CAG repeat length which accounts for approximately 50% of the variation in the age of onset. The instability of the repeat and the tendency to expand further over the generations accounts for the occurrences of new mutations and observed anticipation. CAG expansion is the basis of the worldwide occurrence of HD and was shown to be a sensitive and specific marker for inheritance of the ND gene. A small proportion of clinically affected patients tested lacked CAG expansion, representing misdiagnosis, sample mix-up, clerical error or possible genetic heterogeneity. CAG analysis also allowed for the resolution of recombinant ND chromosomes that previously had suggested the gene was located in the distal candidate region.
Observations and modelling of a clumpy galaxy at z=1.6: Spectroscopic clues to the origin and evolution of chain galaxies
Creators: name: Bournaud, F.
name: Daddi, E.
name: Elmegreen, B. G.
name: Elmegreen, D. M.
name: Nesvadba, N.
name: Vanzella, E.
name: Di Matteo, P.
name: Tiran, L. Le
name: Lehnert, M.
name: Elbaz, D.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We investigate the properties of a clump-cluster galaxy at redshift 1.57. The morphology of this galaxy is dominated by eight star-forming clumps in optical observations, and has photometric properties typical of most clump-cluster and chain galaxies. Its complex asymmetrical morphology has led to the suggestion that this system is a group merger of several initially separate proto-galaxies. We performed H_alpha integral field spectroscopy of this system using SINFONI on VLT UT4. These observations reveal a large-scale velocity gradient throughout the system, but with large local kinematic disturbances. Using a numerical model of gas-rich disk fragmentation, we find that clump interactions and migration can account for the observed disturbed rotation. On the other hand, the global rotation would not be expected for a multiply merging system. We further find that this system follows the stellar mass vs. metallicity, star formation rate and size relations expected for a disk at this redshift, and exhibits a disk-like radial metallicity gradient, so that the scenario of internal disk fragmentation is the most likely one. A red and metallic central concentration appears to be a bulge in this proto-spiral clumpy galaxy. A chain galaxy at redshift 2.07 in the same field also shows disk-like rotation. Such systems are likely progenitors of the present-day bright spiral galaxies, forming their exponential disks through clump migration and disruption and fueling their bulges. Our present results show that disturbed morphologies and kinematics are not necessarily signs of galaxy mergers and interactions, and can instead result from the internal evolution of primordial disks.
description: A&A, accepted. Version with full resolution figures available at http://aramis.obspm.fr/~bournaud/udfr2.pdf -- Animation of clumpy galaxy models available at http://aramis.obspm.fr/~bournaud/cc/cc.html
Comparison of heuristic methods for the identification of switched hybrid systems
Creators: name: Andras Hartmann
name: Lemos, João Miranda
name: Vinga, Susana
Publisher: name: F1000Research
Year: 2015

description: One limiting assumption of many mathematical models describing dynamic systems is that the parameters are time-invariant during the observation period. However, this premise does not necessary hold for many biological systems, for example the existence of intra-individual variability is typical for biological and medical systems,
Hybrid time-varying parameter models comprise both discrete and continuous elements, and provide a suitable framework for biological data modeling. Typically, while the states of the system are modeled with continuous dynamics, the parameters that can be subject to changes exhibit discrete states.

This work considers the problem of parameter identification for switched hybrid systems. The identification of such systems typically results in non-convex optimization problems, where finding the globally optimal solution exhibits exponential computational complexity in the size of the input. Such complexity may however not be tractable even for middle size problems. Another approach involves heuristics in order to deliver estimate in tractable time, with the trade-off that the estimates are only approximate solutions.

Three recently proposed algorithms for switched ARX system identification are compared. We consider segmentation with regularization, Expectation Maximization with Particle Filtering, and identification using sum-of-norms. Statistical measures are introduced in order to quantitatively compare the performance of the different methods on a simulated one-dimensional example. The individual behavior of the methods is also analyzed together with the computational complexity.
These methods can be successfully applied to the identification of several types of biological systems, from pharmacokinetic/pharmacodynamics (PK/PD) models to metabolic networks and cell growth dynamics.

This work was partially supported by by FCT, through IDMEC, under LAETA, project UID/EMS/50022/2013 and InteleGen (PTDC/DTP-FTO/1747/2012).
Διερεύνηση της αλληλεπίδρασης χρηστών ποδηλάτου και πεζών
Creators: name: Πασχαλίδης, Ευάγγελος Πασχάλη
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Ποδηλατιστές
Πεζοί
Εμπλοκή
Bicyclists
Pedestrians
Conflict

description: Σκοπός της παρούσας Διπλωματικής Εργασίας, η οποία εκπονήθηκε στο πλαίσιο του Διατμηματικού Προγράμματος Μεταπτυχιακών Σπουδών: «Σχεδιασμός, Οργάνωση και Διαχείριση Συστημάτων Μεταφορών – ΜΕΤ.Μ.», είναι η διερεύνηση της αλληλεπίδρασης των χρηστών του ποδηλάτου με τους πεζούς. Η συγκεκριμένη διερεύνηση περιλαμβάνει δύο διακριτά τμήματα: τη βιβλιογραφική ανασκόπηση και την έρευνα ερωτηματολογίου που πραγματοποιήθηκε στην περιοχή της Θεσσαλονίκης. Η βιβλιογραφική ανασκόπηση αφορά στη μελέτη συγγραμμάτων, κείμενων εγχειριδίων, οδηγιών, στρατηγικού σχεδιασμού (master plans), άρθρων και παραδοτέων ερευνητικών έργων. Κύριος στόχος στο συγκεκριμένο τμήμα της Διπλωματικής Εργασίας είναι η αποσαφήνιση του ορισμού της «εμπλοκής» πεζών και ποδηλατιστών, ο χωρικός προσδιορισμός του φαινομένου και οι μορφές αλληλεπίδρασης των δύο συγκεκριμένων ομάδων. Η έρευνα ερωτηματολογίου, πραγματοποιήθηκε σε μικτές (για ποδήλατα και πεζούς) υποδομές της περιοχής της Θεσσαλονίκης και απευθύνεται σε ποδηλατιστές. Στόχος ήταν η εξαγωγή συμπερασμάτων για τις συνήθειες των τελευταίων και την αντίληψη τους, όσον αφορά στη συνύπαρξή τους με τους πεζούς και το ζήτημα της εμπλοκής με αυτούς. Σημειώνεται ότι η επεξεργασία των δεδομένων της έρευνας ερωτηματολογίου συνοδεύεται από τους κατάλληλους στατιστικούς ελέγχους.
description: The purpose of the present Thesis, which was realized during the interdepartmental postgraduate program: "Planning, Organization and Management of Transport Systems", is the investigation of the interaction between bicyclists and pedestrians. The specific research is consists of two discrete parts: a review of the bibliography and questionnaire-based survey in the area of Thessaloniki. The state-of-the-art concerns study of books, manuals, guidelines, master plans, papers and deliverables of research projects. The main objective of this specific part of the Thesis is the clarification of the term «conflict» between pedestrians and bicyclists, the spatial determination of this phenomenon and the types of interaction of the two groups. The questionnaire-based survey was realized on shared-use paths in the area of Thessaloniki and it addresses bicyclists. The aim was the obtainment of results concerning the practices of the bicyclists, as well as their perception about their coexistence and conflict with the pedestrians. It must be noted that data processing of the questionnaire-based survey was performed together with the necessary statistical controls.
title: Testing for the absence of causal effects – Mendelian randomization turned around
Creators: name: Vens, Maren
name: Kretschmer, Michelle
name: König, Inke R.
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: 610 Medical sciences; Medicine

description: Mendelian randomization is a robust approach for assessing causal relationships using data from observational studies. Genetic variants are used as instrumental variables for causal inference about the effect of a putative causal risk factor on an outcome. Critically, the genetic variants have to fulfill[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Τεχνητοί αστικοί και κολυμβητικοί υγρότοποι:
Creators: name: Παπαδοπούλου, Αθηνά Ιωάννη
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Τεχνητοί υγρότοποι
Αστικοί υγρότοποι
Φυσικές Πισίνες
Artificial wetlands
Urban torrent water
Natural swimming pools

description: Οι τεχνητοί, όπως και οι φυσικοί υγρότοποι, μέσω των λειτουργιών τους, προσφέρουν πολλές αξίες στον άνθρωπο. Η αξία αναψυχής που μπορεί να προσφέρει ένας υγρότοπος κολύμβησης ειδικά όταν βρίσκεται σε αστικό περιβάλλον είναι πολύτιμη. Η χρήση ιδιωτικών και δημόσιων τεχνητών κολυμβητικών υγροτόπων παρουσιάζει ευρεία εξάπλωση στην Ευρώπη από τη δεκαετία του ‘80 και σήμερα η εξάπλωση συνεχίζεται σε όλες τις ηπείρους. Η περιοχή του πρώην Στρατοπέδου Καρατάσιου στη Δυτική Θεσσαλονίκη που διατρέχεται από το χείμαρρο Ξηροπόταμο κρίνεται ιδανική για τη δημιουργία ενός δημόσιου τεχνητού υγροτόπου για κολύμβηση. Ένα τέτοιο έργο θα προσέφερε τη δυνατότητα αναβάθμισης της περιοχής ενώ θα μπορούσε να εξυπηρετήσει τις ανάγκες των κατοίκων της πόλης και να προσελκύσει επισκέπτες από γειτνιάζουσες περιοχές.
description: Artificial and natural wetlands can offer many values through their functions. Noteworthy is the recreational character that a swimming wetland can provide especially when located in an urban environment. Since the 80’s, the use of private and public artificial swimming wetlands (Natural Swimming Pools) is very common in Europe and have been spread across the continents. As a continuation of this tendency, the former Camp Karatasiou, located in western Thessaloniki and crossed by the torrent Xiropotamos, is considered ideal for the creation of a public artificial wetland for swimming. The above proposal would upgrade the surrounding area both serving the needs of the residents as well as attracting visitors from the neighboring areas.
Response time of a normal-superconductor hybrid system under the step-like pulse bias
Creators: name: Xing, Yanxia
name: Sun, Qing-feng
name: Wang, Jian
Publisher: name: arXiv
Year: 2007
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The response of a quantum dot coupled with one normal lead and a superconductor lead driven by a step-like pulse bias $V_L$ is studied using the non-equilibrium Green function method. In the linear pulse bias regime, the responses of the upwards and downwards bias are symmetric. In this regime the turn-on time and turn-off time are much slower than that of the normal system due to the Andreev reflection. On the other hand, for the large pulse bias $V_L$, the instantaneous current exhibits oscillatory behaviors with the frequency $\hbarΩ=qV_L$. The turn on/off times are in (or shorter than) the scale of $1/V_L$, so they are faster for the larger bias $V_L$. In addition, the responses for the upwards and downwards bias are asymmetric at large $V_L$. The turn-on time is larger than the turn-off time but the relaxation time \cite{note1} depends only on the coupling strength $Γ$ and it is much smaller than the turn-on/off times for the large bias $V_L$.
description: 8 pages, 4 figures, accepted for publication in Phys. Rev. B
MPEC 2024-C94 : 2018 CY2
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: Weighted pseudo-values for partly unobserved group membership in stem cell transplantation studies
Creators: name: Mittlböck, Martina
name: Pötschger, Ulrike
name: Heinzl, Harald
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: cumulative hazard ratio
subject: non-proportional hazards
subject: waiting time bias
subject: inverse probability weighting
subject: 610 Medical sciences; Medicine

description: Studying paediatric leukaemia patients with and without available stem cell donors enables to compare the efficacy of stem cell transplantation with chemotherapy. Since donor search is expensive and takes time, a patient's donor availability status becomes known either when a donor is identified[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Διερεύνηση των χαρακτηριστικών μετακίνησης των ηλικιωμένων πεζών ως προς τη διάσχιση οδών και σηματοδοτούμενων διαβάσεων στο αστικό κέντρο της Θεσσαλονίκης
Creators: name: Παπαζήκου, Αικατερίνη-Εβίτα Κωνσταντίνου
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Ηλικιωμένοι
Διαβάσεις
Ταχύτητα περπατήματος
Elderly
Crosswalks
Walking speed

description: Αντικείμενο της παρούσης διπλωματικής εργασίας είναι η διερεύνηση των χαρακτηριστικών μετακίνησης των ηλικιωμένων πεζών ως προς τη διάσχιση οδών και διαβάσεων στο αστικό κέντρο της Θεσσαλονίκης. Αρχικά, γίνεται εκτεταμένη βιβλιογραφική επισκόπηση, σε διεθνές επίπεδο, σχετικά με τις ταχύτητες περπατήματος, τους χρόνους αντίδρασης στο πράσινο σήμα των πεζών (χρόνοι εκκίνησης), αλλά και σχετικά με τη γενικότερη συμπεριφορά των ηλικιωμένων πεζών κατά τη διάσχιση οδού. Καταγράφονται, επίσης, προτεραιότητες για το σχεδιασμό με στόχο την εξυπηρέτηση πεζή μετακινήσεων, οι διάφοροι τύποι διαβάσεων πεζών, καθώς και αποτελέσματα ποικίλων ερευνών σχετικά με τη συμπεριφορά των πεζών κατά τη διάσχιση οδών. Στη συνέχεια, πραγματοποιείται έρευνα πεδίου μετρήσεων του χρόνου διάσχισης και εκκίνησης των ηλικιωμένων σε τρεις διαβάσεις στο αστικό κέντρο της Θεσσαλονίκης, καθώς και έρευνα ερωτηματολογίου, σε μια προσπάθεια να χαρακτηριστούν οι διαβάσεις, ως προς την ασφάλειά τους, από τους ίδιους τους ηλικιωμένους. Ακολουθεί ποιοτική και στατιστική ανάλυση των αποτελεσμάτων. Τέλος, από την αξιολόγηση όλων των παραπάνω, καταγράφονται τα συμπεράσματα που προκύπτουν και γίνονται προτάσεις, με στόχο τη βελτίωση της προσβασιμότητας στις διαβάσεις που μελετήθηκαν, αλλά και την ενθάρρυνση της μετακίνησης των ηλικιωμένων γενικότερα.
description: The subject of this Thesis is to investigate the mobility patterns of elderly pedestrians, concerning their street crossing behavior, in the urban center of Thessaloniki. Initially, an extensive literature review is made, in international level, in relation to walking speeds, start-up times (i.e., the time from the onset of a Walk signal until the pedestrian steps off the curb) and generally, the seniors’ street crossing behavior. Moreover, priorities for design servicing pedestrian movements, various types of pedestrian crossings, and various research findings regarding the street crossing behavior of pedestrians are identified and discussed. A field study was conducted to quantify the walking speed and start-up time of elderly pedestrians and a questionnaire survey has been, also, realized in three crosswalks in the urban center of Thessaloniki, in an attempt to outline the crossing difficulties that elderly face, as well as, the safety level of these crosswalks from the elderly’s people point of view. A qualitative and statistical analysis of the data collected has been conducted. Finally, taking into consideration all the above, basic conclusions are drawn and recommendations are made, aiming to improve accessibility to the specific sites studied and encourage mobility of elderly people in general.
Orienting dipole moment on molecular dynamics
Creators: name: Bernardin, Alejandro
name: Perez-Acle, Tomas
name: Garate, Jose
name: Yerko Escalona
Publisher: name: F1000Research
Year: 2015

description: Implementation of a new collective variable in COLVARS module, a NAMD's module. We are implementing the dipole angle collective variable.
D6.2 Data Management Plan
Creators: name: Huici, Felipe
name: Carrozzo, Gino
name: Constantin, Ioan
name: Parker, Stephen
name: Martín, Jesús
name: Gaylor Bosson
Publisher: name: Zenodo
Year: 2019
Subjects: unikernels
vm
toolkits
applications
H2020
IoT
Smart Contracts
NFV
Serverless Computing
toolchain
Data Management Plan
DMP

description: The goal of the EU-funded UNICORE project is to develop a common code-base and toolchain that will enable software developers to rapidly create secure, portable, scalable, high-performance solutions starting from existing applications. The key to this is to compile an application into very light-weight virtual machines – known as unikernels – where there is no traditional operating system, only the specific bits of operating system functionality that the application needs. The resulting unikernels can then be deployed
 and run on standard high-volume servers or cloud computing infrastructure. This deliverable defines the project’s data management plan. By and large, Unicore will not rely on any user or senstive data: where needed, tests will be run using already publicly available data sets or synthetic data; this deliverable explain, on a per use case basis, details regarding this. In addition, this deliverable details Unicore’s commitment to making most of its output, be it source code, presentations or scientific papers, publicly available.
title: Analysing propensity score methods on two randomized controlled clinical trials
Creators: name: Dieckmann, Daliah
name: Götte, Heiko
name: Jahn, Antje
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Propensity score methods has been widely used in observational studies and growingly seen as a solution for evaluating treatment effects in non-randomized controlled trials using external controls. They account only for observable confounder via analysis. In contrast to that randomized trials[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Theory of current instability experiments in magnetic Taylor-Couette flows
Creators: name: Ruediger, G.
name: Schultz, M.
name: Shalybkov, D.
name: Hollerbach, R.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We consider the linear stability of dissipative MHD Taylor-Couette flow with imposed toroidal magnetic fields. The inner and outer cylinders can be either insulating or conducting; the inner one rotates, the outer one is stationary. The magnetic Prandtl number can be as small as 10-5, approaching realistic liquid-metal values. The magnetic field destabilizes the flow, except for radial profiles of B$_ϕ$(R) close to the current-free solution. The profile with B$_{in}$=B$_{out}$ (the most uniform field) is considered in detail. For weak fields the TC-flow is stabilized, until for moderately strong fields the m=1 azimuthal mode dramatically destabilizes the flow again. There is thus a maximum value for the critical Reynolds number. For sufficiently strong fields (as measured by the Hartmann number) the toroidal field is always unstable, even for Re=0. The electric currents needed to generate the required toroidal fields in laboratory experiments are a few kA if liquid sodium is used, somewhat more if gallium is used. Weaker currents are needed for wider gaps, so a wide-gap apparatus could succeed even with gallium. The critical Reynolds numbers are only somewhat larger than the nonmagnetic values, so such an experiment would require only modest rotation rates.
description: 8 pages, 4 figures, submitted to Phys. Rev. E
title: Variable selection and shrinkage in low-dimensional data
Creators: name: Kipruto, Edwin
name: Sauerbrei, Willi
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: variable selection
subject: shrinkage
subject: descriptive models
subject: 610 Medical sciences; Medicine

description: Background: Over the last two decades combination of variable selection and shrinkage has grown in popularity due to the need to correct for overestimation bias and to improve the prediction accuracy of a model. Several statistical approaches have been developed such as the non-negative garrote (NNG)[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Generalized Emission Functions for Photon Emission from Quark-Gluon Plasma
Creators: name: Suryanarayana, S. V.
Publisher: name: arXiv
Year: 2006
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The Landau-Pomeranchuk-Migdal effects on photon emission from the quark gluon plasma have been studied as a function of photon mass, at a fixed temperature of the plasma. The integral equations for the transverse vector function (${\bf \tilde{f}(\tilde{p}_\perp)}$) and the longitudinal function ($\tilde{g}({\bf \tilde{p}_\perp})$) consisting of multiple scattering effects are solved by the self consistent iterations method and also by the variational method for the variable set \{$p_0,q_0,Q^2$\}, considering the bremsstrahlung and the $\bf aws$ processes. We define four new dynamical scaling variables, $x^b_T$,$x^a_T$,$x^b_L$,$x^a_L$ for bremsstrahlung and {\bf aws} processes and analyse the transverse and longitudinal components as a function of \{$p_0,q_0,Q^2$\}. We generalize the concept of photon emission function and we define four new emission functions for massive photon emission represented by $g^b_T$, $g^a_T$, $g^b_L$, $g^a_L$. These have been constructed using the exact numerical solutions of the integral equations. These four emission functions have been parameterized by suitable simple empirical fits. In terms of these empirical emission functions, the virtual photon emission from quark gluon plasma reduces to one dimensional integrals that involve folding over the empirical $g^{b,a}_{T,L}$ functions with appropriate quark distribution functions and the kinematic factors. Using this empirical emission functions, we calculated the imaginary part of the photon polarization tensor as a function of photon mass and energy.
description: In nuclear physics journals and arxiv listings, my name used to appear as S.V.S. Sastry. Hereafter, my name will appear as, S.V. Suryanarayana
Additional file 1 of 16-membered ring macrolides and erythromycin induce ermB expression by different mechanisms
Creators: name: He, Weizhi
name: Jiang, Kai
name: Qiu, Hua
name: Liao, Lijun
name: Wang, Shasha
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Science Policy
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Figure S1. (A) Classical model of ermBL dependent regulation of ermB translation in the presence of erythromycin. (B) The second functional leader peptide named ermBL2 found in our previous work. Figure S2. (A)The detail sequence from begining of tac promoter to end of lacZa. (B) The detail sequence of ermB’ truncated mutations used in Figure 2E. Figure S3. The detail sequence of BL-CL and CL-BL constructions. Figure S4. Agar diffusion assays of the degree of induction by Ery in vivo following Ala mutation of ermBL amino acid sequences. Table S1. MIC determinations of E.Coli carrying the PGEX-ermBL-ermB’- lacZα plasmid.
title: Vergleich von Methoden zur Berücksichtigung konkurrierender Ereignisse in der Überlebenszeitanalyse
Creators: name: Sauer, Lennard
name: Hemmelmann, Claudia
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: competing risks
subject: 610 Medical sciences; Medicine

description: Die klassische Überlebenszeitanalyse ist lediglich auf ein bestimmtes Ereignis fokussiert, was jedoch in vielen Fällen wertvolle Informationen auslässt. Ist das interessierende Ereignis zum Beispiel der Tod eines Patienten durch eine bestimmte Krankheit, kann dieses Ereignis durch eine[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)