cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effects of UV rays and natural compound repairs using an ex-vivo human skin model: morphological and genotoxicological analysis
Creators: name: Cornaghi, Brigida
name: Landoni, Federica
name: Baruffaldi Preis, Franz William
name: Calò, Rossella
name: Marabini, Laura
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Ultraviolet radiations; polyphenol compounds; transmission electron microscopy

description: Among the key factors in skin disorders such as wrinkling, dryness and photo-aging, the exposure to solar ultraviolet (UV) radiation plays a central role (1). Recently, compounds rich in polyphenols such as Thymus Vulgaris Leaf (TVL) extract and its major component Thymol (T) have been proposed in the prevention of UV-induced skin damages (2). Experiments were carried out in a human ex-vivo skin model, in which biopsies were obtained from aesthetic surgery of healthy 20-40 year-old women (n=6) after written informed consent (3). After 24 h, samples were pre-treated for 1 h with comparable concentrations of two compounds (TVL: 1.82 μg/mL and T: 1 μg/mL) before being irradiated with different UVB doses (0.24 J/ cm2 to 0.72 J/cm2) or UVA radiation (8 J/cm2 to 32 J/cm2). Samples were harvest- ed 24 h after irradiation and were processed both for light and transmission electron microscopy.Cell proliferation, Lactate Dehydrogenase assay, alkaline comet test, and histone H2AX phosphorylationwere evaluated. Both UVB and UVA induced an early inhibition of cell proliferation and DNA damage compared with respective controls. In particular, UVB rays were always more cytotoxic and genotoxic than UVA. The T-pretreatment showed a reduction of UVB-induced structural/ultrastructural and genotoxic damages. These results suggest that polyphenol fraction of tested substanc- es may be useful for skin photoprotection after UV radiation damage in an ex-vivo human skin model. The present study suggests that this experimental setting can be a reliable approach for safety evaluation of UV skin exposure.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Setaria pumila Roem. et Schult.
Creators: name: Cardona, Àngel Manuel Hernández
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Setaria
Setaria pumila

description: Setaria pumila (Poir.) Roem. et Schult.
(xereix groc). Natural d’una gran part d’Euràsia i introduïda en altres zones del globus. Prospera en conreus, guarets, ermots i herbassars amb una certa humitat edàfica. Ha estat descoberta als dos massissos.
description: Published as part of Cardona, Àngel Manuel Hernández, 2022, Catàleg actualitzat i claus d'identificació de les gramínies de Sant Llorenç del Munt i l'Obac (Barcelona), pp. 64-86 in Nemus 12 on page 74, DOI: 10.5281/zenodo.12170499
L’elicottero marziano supera il test più duro
Creators: Stefano Parisini
Publisher: name: Media Inaf
Year: 2019

«La prossima volta che voleremo, voleremo su Marte», dice MiMi Aung del Jet Propulsion Laboratory della Nasa, a conclusione delle prove di qualificazione per il volo marziano dell’elicottero che andrà su Marte assieme al rover Mars 2020
THE USE OF POTENTIALLY INAPPROPRIATE MEDICATIONS (PIMS) FROM THAILAND CRITERIA AMONG URBAN COMMUNITY-DWELLING ELDERLY: PREVALENCE, PIMS, AND FACTORS ASSOCIATED
Creators: name: Kittipak   Jenghua
name: Harisadee Sangtong
name: Narissara Jaiya
name: Warinat Jaroenteerawit, Apisara Khiewpradang
Publisher: name: Faculty of pharmacy, Silpakorn University
Year: 2019
Subjects: elderly
potentially inappropriate medications
Thailand criteria
prevalence
factors associated

description: Thai Bulletin of Pharmaceutical Sciences, 14, 1(January-December)2019, 49-63
title: ÐÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð°Ð´Ð¼Ð¸Ð½Ð¸ÑÑÑÐ°ÑÐ¸Ð²Ð½Ð¾-Ð¶Ð¸Ð»Ð¾Ð³Ð¾ ÑÐ»ÑÐ¶ÐµÐ±Ð½Ð¾Ð³Ð¾ ÐºÐ¾ÑÐ¿ÑÑÐ° Ð³Ð¾ÑÐ½Ð¾Ð»ÑÐ¶Ð½Ð¾Ð³Ð¾ ÐºÑÑÐ¾ÑÑÐ°
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°ÑÐ°ÑÐ¾Ð², ÐÐ³Ð¾ÑÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð³ÐµÐ½ÐµÑÐ°Ð»ÑÐ½ÑÐ¹ Ð¿Ð»Ð°Ð½
Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð¾ÑÐ½Ð¾Ðµ ÑÐµÑÐµÐ½Ð¸Ðµ
Ð¿Ð»Ð¸ÑÐ° Ð¿ÐµÑÐµÐºÑÑÑÐ¸Ñ

description: ÐÐ´Ð¼Ð¸Ð½Ð¸ÑÑÑÐ°ÑÐ¸Ð²Ð½Ð¾-Ð¶Ð¸Ð»Ð¾Ð¹ ÑÐ»ÑÐ¶ÐµÐ±Ð½ÑÐ¹ ÐºÐ¾ÑÐ¿ÑÑ Ð³Ð¾ÑÐ½Ð¾Ð»ÑÐ¶Ð½Ð¾Ð³Ð¾ ÐºÑÑÐ¾ÑÑÐ°. ÐÑÑÐ¸ÑÐµÐºÑÑÑÐ½Ð¾-ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÐ½Ð°Ñ ÑÐ°ÑÑÑ Ð²ÐºÐ»ÑÑÐ°ÐµÑ Ð² ÑÐµÐ±Ñ ÐºÑÐ°ÑÐºÑÑ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÑ ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð¾Ð±ÑÐµÐºÑÐ°, ÐºÑÐ°ÑÐºÑÑ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÑ ÑÑÐ»Ð¾Ð²Ð¸Ð¹ ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ð°, Ð¾Ð±ÑÐµÐ¼Ð½Ð¾-Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð¾ÑÐ½Ð¾Ðµ Ð¸ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð²Ð½Ð¾Ðµ ÑÐµÑÐµÐ½Ð¸Ñ Ð·Ð´Ð°Ð½Ð¸Ñ, ÑÐ°ÑÑÐµÑ Ð³Ð»ÑÐ±Ð¸Ð½Ñ Ð¿ÑÐ¾Ð¼ÐµÑÐ·Ð°Ð½Ð¸Ñ Ð³ÑÑÐ½ÑÐ° Ð¸ Ð³Ð»ÑÐ±Ð¸Ð½Ñ Ð·Ð°Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð¿Ð¾Ð´Ð¾ÑÐ²Ñ ÑÑÐ½Ð´Ð°Ð¼ÐµÐ½ÑÐ¾Ð². B ÑÐ°ÑÑÐµÑÐ½Ð¾-ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð²Ð½Ð¾Ð¹ ÑÐ°ÑÑÐ¸ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½ ÑÐ±Ð¾Ñ Ð½Ð°Ð³ÑÑÐ·Ð¾Ðº. Ð ÑÐ¾Ð¼ ÑÐ¸ÑÐ»Ðµ ÑÐ°ÑÑÑÑ ÑÑÐ½Ð´Ð°Ð¼ÐµÐ½ÑÐ°. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÑÐ°ÑÐ°ÐºÑÐµÑÐ½ÑÐµ ÑÐ·Ð»Ñ.
Scoperte due galassie senza materia oscura
Creators: Paolo Soletta
Publisher: name: Media Inaf
Year: 2019

Fino a oggi si conosceva solo Ngc 1502-Df2. Ora lo stesso team di scienziati che aveva firmato l’anno scorso la scoperta non solo la conferma, ma ne aggiunge una seconda: Ngc 1502-Df4. Entrambe galassie ultra diffuse, il moto dei loro ammassi globulari suggerisce che siano fatte esclusivamente – o quasi – di materia barionica
Symmetry-Breaking and Symmetry-Restoring Dynamics of a Mixture of Bose-Einstein Condensates in a Double Well
Creators: name: Satija, Indubala I
name: Naudus, Philip
name: Balakrishnan, Radha
name: Heward, Jeffrey
name: Edwards, Mark
name: Clark, and Charles W
Publisher: name: arXiv
Year: 2008
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the coherent nonlinear tunneling dynamics of a binary mixture of Bose-Einstein condensates in a double-well potential. We demonstrate the existence of a new type of mode associated with the "swapping" of the two species in the two wells of the potential. In contrast to the symmetry breaking macroscopic quantum self-trapping (MQST) solutions, the swapping modes correspond to the tunneling dynamics that preserves the symmetry of the double well potential. As a consequence of two distinct types of broken symmetry MQST phases where the two species localize in the different potential welils or coexist in the same well, the corresponding symmetry restoring swapping modes result in dynamics where the the two species either avoid or chase each other. In view of the possibility to control the interaction between the species, the binary mixture offers a very robust system to observe these novel effects as well as the phenomena of Josephson oscillations and pi-modes
БИОЛОГИЧЕСКАЯ ХАРАКТЕРИСТИКА И РЕЗИСТЕНТНОСТЬ К ДЕЗИНФЕКТАНТАМ ПСЕВДОМОНАД, ВЫДЕЛЕННЫХ ОТ ПАЦИЕНТОВ ОЖОГОВОГО СТАЦИОНАРА
Creators: name: Сообщество рецензентов Международного научно-исследовательского журнала
Publisher: name: ИП Соколова М.В.
Year: 2022
Subjects: псевдомонады
ожоговый стационар
дезинфектанты

description: Международный научно-исследовательский журнал 1(115) 1.2022, №1(115) (2022)
title: The role of nursing in multimorbidity care
Creators: name: McParland, Christopher Robert
Publisher: name: University of Glasgow
Year: 2024

description: Background

Multimorbidity (the co-occurrence of two or more chronic conditions in the same person) affects around one in three persons, and it is strongly associated with a range of negative outcomes including worsening physical function, increased health care use, and premature death. Due to the way healthcare is provided to people with multimorbidity, treatment can become burdensome, fragmented and inefficient. In people with palliative conditions, multimorbidity is increasingly common. Better models of care are needed.

Methods

A mixed-methods programme of research designed to inform the development of a nurse-led intervention for people with multimorbidity and palliative conditions. A mixed-methods systematic review explored nurse-led interventions for multimorbidity and their effects on outcomes. A cross-sectional study of 63,328 emergency department attenders explored the association between multimorbidity, complex multimorbidity (≥3 conditions affecting ≥3 body systems), and disease-burden on healthcare use and inpatient mortality. A focussed ethnographic study of people with multimorbidity and life-limiting conditions and their carers (n=12) explored the concept of treatment burden.

Findings

Nurse-led interventions for people with multimorbidity generally focus on care coordination (i.e., case management or transitional care); patients view them positively, but they do not reliably reduce health care use or costs. Multimorbidity and complex multimorbidity were significantly associated with admission from the emergency department and reattendance within 30 and 90 days. The association was greater in those with more conditions. There was no association with inpatient mortality. People with multimorbidity and palliative conditions experienced treatment burden in a manner consistent with existing theoretical models. This thesis also noted the effect of uncertainty on the balance between capacity and workload and proposes a model of how these concepts relate to one another.

Discussion

This thesis addresses a gap in what is known about the role of nurses in providing care to the growing number of people with multimorbidity. A theory-based nurse-led intervention is proposed which prioritises managing treatment burden and uncertainty.

Conclusions

Nursing in an age of multimorbidity necessitates a perspective shift which conceptualises chronic conditions as multiple overlapping phenomena situated within an individual. The role of the nurse should be to help patients navigate the complexity of living with multiple chronic conditions.
Open-Source Portable Photodetection Platform
Creators: name: Pohanka, Miroslav
name: Kerestes, Ondrej
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Analytical Chemistry
subject: FOS: Chemical sciences
subject: Physical Sciences and Mathematics
subject: Environmental Monitoring
subject: Environmental Sciences
subject: Chemistry
subject: open-source
subject: cholinesterase
subject: photometry
subject: pesticide
subject: point-of-care test
subject: field-analysis
subject: affordable

description: This project presents Open-Source Portable Photometric Platform. The Arduino Uno based photometer with programmable RGB LED as a light source. User can measure a colourful solutions and carry out enzymatic assays.
Evaluation of the effects of a dynamic culture on osteogenic differentiation of oral-periosteal cells grown on PLGA sponges
Creators: name: Ceccarelli, Gabriele
name: Benedetti, Laura
name: Graziano, Antonio
name: Alloni, Maurizio
name: Silvani, Giulia
name: Sampaolesi, Maurilio
name: Micheletti, Piero
name: Visai, Livia
name: Cusella De Angelis, Maria Gabriella
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Oral-periosteal cells; PLGA biomaterials; Fisiograft®; dynamic culture

description: Oral-periosteum derived stem cells represent an innovative cell source for bone tissue engineering applications in terms of accessibility and self-commitment towards osteogenic lineage [1]. In this scenario, biomaterials play a pivotal role in tissue engineering in supporting stem cells growth and regeneration of tissue defects [2]. Among these biomaterials, Fisiograft®, a synthetic co-polymer composed of polylactic and polyglycholic acids produced by Ghimas (Bologna, Italy), is highly biocom- patible and completely absorbed within 4-6 months. In particular, Fisiograft® sponges are normally used in dental applications to fix completely periodontal defects without damage Schneider’s membrane. We evaluated the osteogenic potential of Fisiograft® sponges on oral-periosteal cells derived from patients undergoing dental extractions. For this purpose, we created a dynamic culture based on a rotating apparatus in which we seeded periosteal cells with Fisiograft® sponges for 7, 14 and 21 days without adding osteogenic supplement in the medium. Osteoblast differen- tiation of cells was evaluated by Alizarin Red S staining and by qRT-PCR on genes involved in bone development. Results show that Fisograft® sponges promote greater osteogenic differentiation of cells in the dynamic culture with respect to standard condition already at 14 days, as demonstrated by Alizarin Red staining. BMP-2 and Osteoprotegerin genes are highly expressed by cells grown on Fisiograft® sponges in dynamic culture at 14 days with respect to plastic culture. Taken together, these results confirm the osteogenic potential of Fisiograft® sponges in accelerating the dif- ferentiation of cells to an osteoblast phenotype (already to 14 days of culture) without any osteogenic induction. The combination of this PLGA biomaterial and oral-peri- osteal cells could represent a promising bio-complex in maxillo-facial tissue repair.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Simulation of depositions of a Lennard-Jones cluster on a crystalline surface
Creators: name: Saitoh, Kuniyasu
name: Hayakawa, Hisao
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Depositions of amorphous Lennard-Jones clusters on a crystalline surface are numerically investigated. From the results of the molecular dynamics simulation, we found that the deposited clusters exhibit a transition from multilayered adsorption to monolayered adsorption at a critical incident speed. Employing the energy conservation law, we can explain the behavior of the ratio of the number of atoms adsorbed on the substrate to the cluster size. The boundary shape of the deposited cluster depends strongly on the incident speed and some unstable modes grow during the spread of the deposited cluster on the substrate. We also discuss the wettability between different Lennard-Jones atoms.
description: 14 pages, 9 figures ; will appear in Progress of Theoretical Physics, Vol. 122, No 5
L’osservatorio di La Silla compie 50 anni
Creators: Redazione Eso
Publisher: name: Media Inaf
Year: 2019

La costruzione di La Silla sulla vetta della montagna cilena Cinchado-Nord, alla periferia del deserto di Atacama, iniziò nel 1965, tre anni dopo la fondazione dello European Southern Observatory. Fu inaugurato nel 1969, ed è ancora oggi all’avanguardia, fornendo dati per oltre duecento articoli ogni anno
Bilayered scaffolds colonized with dental pulp stem cells for osteochondral tissue engineering application
Creators: name: Bertoni, Laura
name: Zavatti, Manuela
name: Resca, Elisa
name: Maraldi, Tullia
name: Beretti, Francesca
name: Carnevale, Gianluca
name: Pisciotta, Alessandra
name: De Pol, Anto
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: DPSC; fibroin; collagen; osteochondral regeneration

description: The development of osteochondral tissue engineered interfaces would be a novel treatment for traumatic injuries and aging associated diseases that affect joints [1]. Dental Pulp Stem Cells (DPSC) are a promising alternative source in cell-based tissue engineering for the easily recruitment, the self-renewal and differentiation potential, being able to differentiate toward chondrogenic and osteogenic lineage [2]. The aim of this study was to develop scaffold that would support an osteochon- dral interface. DPSCs, isolated from dental pulp by selection with c-Kit-CD34 and STRO1 antibodies, were either cultured on fibroin and collagen scaffolds and differ- entiated into osteogenic cells or encapsulated in alginate and differentiated into chondrogenic cells. After 3 weeks of culture, the differentiation of the cell-scaffold con- structs was analyzed by histology and immunofluorescence. The cell seeded scaffolds were then brought together (fibroin+alginate and collagen+alginate) in order to form a combination that would provide a supportive scaffold for bone formation as well as a soft matrix for cartilage growth. The resulting single constructs were cultured for 2 weeks in a osteochondral media, developed by combining some of the growth factors and nutrients of osteoand chondrogenic media. The constructs were then characterized for expression of bone and cartilage specific markers to evaluate the capability of the cells to not dedifferentiate in the new cultured conditions. We demonstrated that both collagen and fibroin appear to be excellent scaffold for cells differentiated into osteogenic lineage, although they have different structural characteristics. Similarly, the alginate has allowed cells to produce ECM-rich in collagen II and aggrecan during chondrogenic differentiation. Moreover DPSC in the bilay- ered constructs remain viable and differentiated even in the osteochondral medium. Thus the integrated fibroin-alginate or collagen-alginate proved to be functional in vitro and may lead to the development of new strategies for osteochondral repair and regeneration.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð¸Ð¹ Ð¿Ð¾ ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¾ÑÐ¼ ÐºÑÐµÐ´Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÑÐ¸Ð´Ð¸ÑÐµÑÐºÐ¸Ñ Ð»Ð¸Ñ (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ Â«Ð¡Ð±ÐµÑÐ±Ð°Ð½ÐºÂ»)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: Ð¯ÑÐ°Ð»Ð¸ÐµÐ², ÐÐµÐ»Ð¸
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÐºÑÐµÐ´Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
ÑÑÐ¸Ð´Ð¸ÑÐµÑÐºÐ¸Ðµ Ð»Ð¸ÑÐ°
ÑÐ¾ÑÐ¼Ñ ÐºÑÐµÐ´Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ
Ð¾Ð²ÐµÑÐ´ÑÐ°ÑÑ

description: Ð¦ÐµÐ»Ñ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ â ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ð¹, Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð½ÑÑ Ð½Ð° ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ðµ ÑÐ¾ÑÐ¼ ÐºÑÐµÐ´Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÑÐ¸Ð´Ð¸ÑÐµÑÐºÐ¸Ñ Ð»Ð¸Ñ Ð² ÐÐÐ Â«Ð¡Ð±ÐµÑÐ±Ð°Ð½ÐºÂ».
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ÐÑÑÐ²Ð»ÐµÐ½Ñ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ, ÐºÐ¾ÑÐ¾ÑÑÐµ Ð¿ÑÐµÐ¿ÑÑÑÑÐ²ÑÑÑ Ð½Ð° Ð´Ð°Ð½Ð½ÑÐ¹ Ð¼Ð¾Ð¼ÐµÐ½Ñ Ð¿Ð¾Ð»Ð½Ð¾ÑÐµÐ½Ð½Ð¾Ð¼Ñ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð¿ÑÐ¾ÑÐµÑÑÑ ÐºÑÐµÐ´Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÑÐ¸Ð´Ð¸ÑÐµÑÐºÐ¸Ñ Ð»Ð¸Ñ.
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Favio Bortoletto ci ha lasciato
Creators: Redazione Media Inaf
Publisher: name: Media Inaf
Year: 2019

Molteplici sono stati i campi in cui ha dato il suo contributo, come lo sviluppo dei rivelatori a stato solido e l’ottica attiva e la messa in esercizio del Telescopio Nazionale Galileo. Bortoletto è stato anche uo dei pilastri della missione Euclid
On Functionality of Visibly Pushdown Transducers
Creators: name: Filiot, Emmanuel
name: Raskin, Jean-François
name: Reynier, Pierre-Alain
name: Servais, Frédéric
name: Talbot, Jean-Marc
Publisher: name: arXiv
Year: 2010
Subjects: subject: Formal Languages and Automata Theory (cs.FL)
subject: FOS: Computer and information sciences

description: Visibly pushdown transducers form a subclass of pushdown transducers that (strictly) extends finite state transducers with a stack. Like visibly pushdown automata, the input symbols determine the stack operations. In this paper, we prove that functionality is decidable in PSpace for visibly pushdown transducers. The proof is done via a pumping argument: if a word with two outputs has a sufficiently large nesting depth, there exists a nested word with two outputs whose nesting depth is strictly smaller. The proof uses technics of word combinatorics. As a consequence of decidability of functionality, we also show that equivalence of functional visibly pushdown transducers is Exptime-Complete.
description: 20 pages
title: Ð¡ÑÐ°Ð²Ð½Ð¸ÑÐµÐ»ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐ¸ÑÑÐµÐ¼ Ð½Ð°Ð»Ð¾Ð³Ð¾Ð¾Ð±Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð´Ð¾Ñ Ð¾Ð´Ð¾Ð² ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¸Ñ Ð»Ð¸Ñ Ð² Ð Ð¾ÑÑÐ¸Ð¸ Ð¸ ÐÐ¸ÑÐ°Ðµ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: Ð¯Ð½, ÐÐ¸
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð½Ð°Ð»Ð¾Ð³Ð¾Ð¾Ð±Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ
ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¸Ðµ Ð»Ð¸ÑÐ°
Ð½Ð°Ð»Ð¾Ð³ Ð½Ð° Ð´Ð¾Ñ Ð¾Ð´Ñ ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¸Ñ Ð»Ð¸Ñ
ÐºÐ¸ÑÐ°Ð¹

description: ÐÑÐµÐ´Ð¼ÐµÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ ÑÐ¸ÑÑÐµÐ¼Ð° Ð½Ð°Ð»Ð¾Ð³Ð¾Ð¾Ð±Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð´Ð¾ÑÐ¾Ð´Ð¾Ð² ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¸Ñ Ð»Ð¸Ñ.
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Asteroide condannato all’autodistruzione
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2019

Probabile vittima dell’effetto Yorp, il piccolo asteroide Gault – circa 4 km di diametro – ha perso in pochi mesi, nel corso di due distinti eventi, oltre sette milioni di tonnellate di materia, lasciandosela alle spalle sotto forma di due lunghe scie di polvere
Additional file 2 of The effects of the prognostic biomarker SAAL1 on cancer growth and its association with the immune microenvironment in lung adenocarcinoma
Creators: name: Tong, Song
name: Jiang, Ni
name: Wan, Jun-Hao
name: Chen, Chong-Rui
name: Wang, Si-Hua
name: Wu, Chuang-Yan
name: Guo, Qiang
name: Xiao, Xiao-Yue
name: Huang, Huan
name: Zhou, Ting
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 2 Figure S1. SAAL1 expression in paired pan-cancer tissues. (A) TCGA; (B) XENA-TCGA; (C) TCGA. Note: TCGA, the cancer genome atlas. Figure S2. Increased SAAL1 expression was associated with poorer PFI in LAC patient subgroups. Note: PFI, progression-free interval; LAC, lung adenocarcinoma. Figure S3. PPI network of SAAL1-associated genes. Note: PPI, protein-protein interaction. Figure S4. The expression levels of 21 SAAL1-related genes in paired LAC tissues. Note: LAC, lung adenocarcinoma. Figure S5. SAAL1 expression levels were significantly correlated with the immune cells. (A) Neutrophils; (B) Th1 cells; (C) NK CD56dim cells; (D) pDC; (E) Cytotoxic cells; (F) aDC; (G) TReg; (H) Macrophages; (I) T cells. Table S1. Functions of SAAL1-associated genes.
Positive current noise cross-correlations in capacitively coupled double quantum dots with ferromagnetic leads
Creators: name: Dong, Bing
name: Lei, X. L.
name: Horing, N. J. M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We examine cross-correlations (CCs) in the tunneling currents through two parallel interacting quantum dots coupled to four independent ferromagnetic electrodes. We find that when either one of the two circuits is in the parallel configuration with sufficiently strong polarization strength, a new mechanism of dynamical spin blockade, i.e., a spin-dependent bunching of tunneling events, governs transport through the system together with the inter-dot Coulomb interaction, leading to a sign-reversal of the zero-frequency current CC in the dynamical channel blockade regime, and to enhancement of positive current CC in the dynamical channel anti-blockade regimes, in contrast to the corresponding results for the case of paramagnetic leads.
description: 9 pages, 3 figures
Morality and Malleability of Racism- Conservatism
Creators: name: Rose, Hope
name: King, Laura A.
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Personality and Social Contexts

description: Do people believe a racist’s attitudes can be changed? And does this matter if the racist is perceived as politically conservative?
Hypoxia induces Galectin-3 and Bcl-2 over-expression in human umbilical vein endothelial cells (HUVECs)
Creators: name: Di Vito, Anna
name: Mignogna, Chiara
name: Bilotta, Anna
name: Camastra, Caterina
name: Trapasso, Francesco
name: Brunetti, Antonio
name: Aversa, Ilenia
name: Donato, Giuseppe
name: Barni, Tullio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: HUVEC; hypoxia; Galectin-3; Bcl-2

description: Angiogenesis, the growth of new blood vessels from pre-existing endothelium, is a critical phenomenon occurring during development and tissue regeneration. In pathological conditions such as inflammation and malignancies, hypoxia represent one of the most important driver of angiogenesis, mainly via the release of nitric oxide [1]. Here we investigate the behavior of human umbilical vein endothelial cells (HUVECs) treated with 100 mM CoCl2 for 24 hours, a condition mimicking hypoxia by the stabilization of HIF-1α and HIF-2α [2,3]. MTT and wound healing assays were performed to evaluate cell migration and proliferation, respectively, while Bcl-2 and Galectin-3 expression levels were analyzed by western blotting. We showed that hypoxic condition resulted in reduced proliferation and migration with increased expression of Galectin-3 and Bcl-2. These preliminary results provide new insights in the characterization of Galectin-3/Bcl-2 interplay in endothelial cell survival under hypoxic condition, and will contribute to a better understanding of hypoxia influences on tumor angiogenesis.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
On the temperature dependence of the paramagnetic resonance line shape function in the case of the Ising model
Creators: name: Yu-Yang, Lee
Publisher: name: University of British Columbia
Year: 2012

description: The adequacy of the approximation method used by McMillan and Opechowski (1960) in their theoretical study of the temperature dependence of the paramagnetic resonance line shape function is very difficult to ascertain for the case of a typical paramagnetic crystal. For this reason the approximation method has been investigated, in this thesis, for the very simple case of the one-dimensional Ising model. Exact expressions for the line shape function of the model are compared with expressions obtained by the above mentioned approximation method. The agreement between the two expressions is found to be very good for all temperatures, and in particular, for extremely low temperatures.
Modulation of epidermal proliferation and terminal differentiation in a promising ex vivo human skin model mimicking a psoriatic microenvironment
Creators: name: Donetti, Elena
name: Mastroianni, Nicolino
name: Cornaghi, Laura
name: Arnaboldi, Francesca
name: Landoni, Federica
name: Prignano, Francesca
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Psoriasis; cytokines; keratins

description: Epidermal keratinocyte hyperproliferation is one of the key features involved in the formation/progression of psoriatic lesions and is driven by cytokines, among which TNF-α, IL-17, IL-22 and IL-23, secreted by both activated resident immune cells and keratinocytes (1). The network orchestrated by these cytokines is essential for the communication between resident cells and infiltrating cells and is due to redun- dancy, synergism and, sometimes, the reciprocal antagonism of cytokines. The aims of our study were to investigate whether the exposure of normal human skin to four main psoriatic cytokines, i.e. TNF-α, IL-17, IL-22, and IL-23 (cytokine mix) induced i) a modulation of epidermal proliferation and ii) a modification of keratinocyte terminal differentiation (TD). Human skin samples (n=5) obtained from healthy 20-40 years- old women after plastic surgery, were exposed to the cytokine mix in a Transwell sys- tem at air-liquid interface as previously described (2). For each patient a control (ctr) group was not exposed to cytokine mix. Samples were harvested 5 (T5), 24 (T24), 48 (T48) and 72 (T72) hours after cytokine stimulation, processed for paraffin embedding and immunofluorescence analysis for the quantitative analysis of epidermal proliferation and the expression of the TD biomarkers, keratin (K) 10 and 17. A decrease of cell proliferation was evident starting from T5 in samples exposed to cytokine mix and was progressively more marked at later time points (T5 ctr 47.44 ± 6.90 vs mix 23.07 ± 8.84; T24 ctr 41.12 ± 12.78 vs mix 12.16 ± 1.53; T48 ctr 25.88 ± 10.21 vs mix 2.19 ± 2.44; T72 ctr 10.49 ± 2.52 vs mix 0.65 ± 1.02) (p<0.05). K17 expression was evi- dent in samples exposed to the cytokine mix. Altogether the present results suggest that cell proliferation inhibition and K17 expression could be regarded as the basis for a later response to injury leading to psoriatic lesion formation/progression. In conclu- sion, this model allows to investigate the intimate interplay among different psoriatic cytokines and new insights may be of potential value for future clinical treatments.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Setaria verticillata
Creators: name: Cardona, Àngel Manuel Hernández
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Setaria
Setaria verticillata

description: Setaria verticillata (L.) P. Beauv.
(xereix aferradís). De distribució subcosmopolita. Creix en horts, vergers, jardins, regalls i herbassars nitròfils. Apareix amb freqüència a les zones baixes i mitjanes, en els hàbitats indicats.
description: Published as part of Cardona, Àngel Manuel Hernández, 2022, Catàleg actualitzat i claus d'identificació de les gramínies de Sant Llorenç del Munt i l'Obac (Barcelona), pp. 64-86 in Nemus 12 on page 74, DOI: 10.5281/zenodo.12170499
Fiumi in piena nel passato di Marte
Creators: Giuseppe Fiasconaro
Publisher: name: Media Inaf
Year: 2019

Più vasti di quelli presenti oggi sulla Terra, in numero elevato, più recenti di quanto si pensasse e con un flusso impetuoso: è la “fotografia” dei corsi d'acqua del passato marziano che sembra mettere in crisi gli attuali modelli climatici del pianeta. A ottenerla, un team di scienziati dell'Università di Chicago i cui risultati sono stati pubblicati su Science Advances
Cinque piccole lune di Saturno viste da vicino
Creators: Ufficio stampa Inaf
Publisher: name: Media Inaf
Year: 2019

I dati raccolti dalla sonda Nasa/Esa/Asi Cassini prima del tuffo finale sul pianeta, pubblicati oggi su Science, mostrano la composizione superficiale di cinque satelliti naturali poco conosciuti. Tra gli autori dello studio anche alcuni ricercatori Inaf
title: ÐÐ½Ð¾Ð³Ð¾ÐºÐ²Ð°ÑÑÐ¸ÑÐ½ÑÐ¹ Ð¶Ð¸Ð»Ð¾Ð¹ Ð´Ð¾Ð¼ ÑÐ¾ Ð²ÑÑÑÐ¾ÐµÐ½Ð½ÑÐ¼Ð¸ Ð¿Ð¾Ð¼ÐµÑÐµÐ½Ð¸ÑÐ¼Ð¸ Ð¸ Ð¿Ð¾Ð´Ð·ÐµÐ¼Ð½Ð¾Ð¹ Ð°Ð²ÑÐ¾ÑÑÐ¾ÑÐ½ÐºÐ¾Ð¹
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ¾Ð±ÐµÐµÐ², ÐÐ°Ð¸ÑÐ±ÐµÐº
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ð¾
Ð¶Ð¸Ð»Ð¾Ð¹ Ð´Ð¾Ð¼
ÐºÐ²Ð°ÑÑÐ¸ÑÐ°

description: ÐÐµÑÐµÑÐ³Ð¾Ñ - Ð³Ð¾ÑÐ¾Ð´ Ð² Ð Ð¾ÑÑÐ¸Ð¸, Ð¼ÑÐ½Ð¸ÑÐ¸Ð¿Ð°Ð»ÑÐ½Ð¾Ðµ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð² ÑÐ¾ÑÑÐ°Ð²Ðµ ÐÐµÑÑÐ¾Ð´Ð²Ð¾ÑÑÐ¾Ð²Ð¾Ð³Ð¾ ÑÐ°Ð¹Ð¾Ð½Ð° Ð³Ð¾ÑÐ¾Ð´Ð° ÑÐµÐ´ÐµÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð·Ð½Ð°ÑÐµÐ½Ð¸Ñ Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³Ð°. Ð Ð°ÑÐ¿Ð¾Ð»Ð¾Ð¶ÐµÐ½ Ð½Ð° ÑÐ¶Ð½Ð¾Ð¼ Ð±ÐµÑÐµÐ³Ñ Ð¤Ð¸Ð½ÑÐºÐ¾Ð³Ð¾ Ð·Ð°Ð»Ð¸Ð²Ð°. ÐÑÑÐ¿Ð½ÑÐ¹ ÑÑÑÐ¸ÑÑÐ¸ÑÐµÑÐºÐ¸Ð¹, Ð½Ð°ÑÑÐ½ÑÐ¹ Ð¸ ÑÑÐµÐ±Ð½ÑÐ¹ ÑÐµÐ½ÑÑ Ðº Ð·Ð°Ð¿Ð°Ð´Ñ Ð¾Ñ Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³Ð°, Ð² 29 ÐºÐ¼ Ð¿Ð¾ Ð¶ÐµÐ»ÐµÐ·Ð½Ð¾Ð¹ Ð´Ð¾ÑÐ¾Ð³Ðµ. Ð Ð°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÐµÐ¼ÑÐ¹ ÑÑÐ°ÑÑÐ¾Ðº ÑÐ°ÑÐ¿Ð¾Ð»Ð¾Ð¶ÐµÐ½ Ð² Ð³. ÐÐµÑÑÐ¾Ð´Ð²Ð¾ÑÑÐµ, ÑÐ». ÐÐµÑÐµÑÐ³Ð¾ÑÑÐºÐ°Ñ Ð´.Ð®Ð°, Ð½Ð° ÑÐµÑÑÐ¸ÑÐ¾ÑÐ¸Ð¸ Ð´ÐµÐ¹ÑÑÐ²ÑÑÑÐµÐ¹ Ð°Ð²ÑÐ¾ÑÑÐ¾ÑÐ½ÐºÐ¸. Ð£ÑÐ°ÑÑÐ¾Ðº Ð·Ð°Ð½ÑÑ ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ð¼Ð¸ Ð·Ð´Ð°Ð½Ð¸ÑÐ¼Ð¸ Ð³Ð°ÑÐ°Ð¶ÐµÐ¹, ÑÐºÐ»Ð°Ð´Ð°Ð¼Ð¸, ÑÐºÐ»Ð°Ð´Ð¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¼ Ð»Ð¾Ð¼Ð¾Ð¼ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð½, ÑÐ°Ð·Ð²Ð¸ÑÐ¾Ð¹ ÑÐµÑÑÑ Ð¿Ð¾Ð´Ð·ÐµÐ¼Ð½ÑÑ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¹, ÑÐ°ÑÑÐ¸ÑÐ½Ð¾ Ð·Ð°Ð°ÑÑÐ°Ð»ÑÑÐ¸ÑÐ¾Ð²Ð°Ð½.
Обеспечение безопасности функционирования объектов территориальных органов Федерального казначейства
Creators: name: Демидова, Елена
Publisher: name: ИП Соколова М.В.
Year: 2022
Subjects: безопасность
объекты казначейства
финансирование
систем защиты объектов
мониторинг
IP – видеонаблюдение
интеллектуальные системы
Интернет вещей
контроль
управление охраной объектов
цифровизация.

description: Международный научно-исследовательский журнал 1(115) 1.2022, №1(115) (2022)
Identification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition
Creators: name: Bellissimo, Teresa
name: Fontemaggi, Giulia
name: Donzelli, Sara
name: Iosue, Ilaria
name: Benassi, Barbara
name: Bellotti, Giorgio
name: Blandino, Giovanni
name: Fazi, Francesco
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: MicroRNAs; myeloid differentiation; ribosomal/polysomal fractions; PLK1

description: During hematopoiesis it is clearly emerging that microRNAs are integrated with target genes in regulatory circuitries involved in the decisions regarding the ability to self-renew and to generate a differentiated progeny in hematopoietic cells including myeloid cells (1). microRNAs are able to modulate genes expression mainly by tuning the rate of proteins’ synthesis inhibiting the initiation or later stages of translation. A change in the association of an mRNA with polysomes is indicative of changes in its translation state. For instance, a block in translational initiation would result in reduced ribo- some density on the affected mRNA and a shift toward the lower-density fractions of the gradient (2). Prediction algorithms usually provide hundreds of target genes for each microRNA and the identification of reliable target genes is feasible only through single-gene approaches. To identify microRNA-mRNA networks relevant for the transition from myeloblasts to monocytes, we here evaluated the localization of microRNAs and mRNAs in ribosomal/polysomal cell fractions obtained by sucrose density gradient centrifugation from the myeloblastic cell line HL60 induced or not to differentiate by 1,25-dihydroxyvitamin D3 treatment to induce monocyte/macrophage differentiation. The co-localization of miRNAs and predicted target mRNAs in low-density riboso- mal fractions is strongly indicative of their functional interaction. Intersection between mRNAs shifted across the fractions after treatment with putative target genes of modulated microRNAs showed a series of molecular net- works relevant for the monocyte cell fate determination, as for example the post-tran- scriptional regulation of the Polo-like kinase 1 (PLK1) by miR-22-3p and let-7e-5p. The disclosing of new molecular players involved in myeloid cell fate determina- tion paves the way for the identification of new potentially interesting molecular tar- gets for the treatment of acute myeloid leukemia cells.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Dalla Ue 2,5 milioni di euro per Bianca Poggianti
Creators: Ufficio stampa Inaf
Publisher: name: Media Inaf
Year: 2019

Il progetto “Gasp”, guidato dalla ricercatrice dell’Inaf di Padova, è stato finanziato con un Advanced Grant dello European Research Council: cinque anni garantiti per lo studio dei meccanismi di rimozione del gas delle galassie
A synergic effect of alginate and hypoxia-inducing ions on chondrogenic differentiation in adipose derived mesenchymal stem cells
Creators: name: Focaroli, Stefano
name: Salvatore, Viviana
name: Teti, Gabriella
name: Ingrà, Laura
name: Falconi, Mirella
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Stem cells; chondrogenic differentiation; alginate

description: Cartilage is a highly organized tissue with complex biomechanical properties, but since it has a poor intrinsic capacity of self-healing, injuries at this site usually lead to several problems, often ending in disabling symptoms. Although, different approach- es have been proposed, even now cartilage repair represents a great challenge for orthopaedic surgeons (1, 2). One of the promising approach is given from tissue engineering, employing the combination of biomaterials and cell therapy to develop new therapeutic strategies. In this paper, we describe the behaviour of human adipose derived mesenchymal stem cells encapsulated into Ca/Co alginate beads as potential chondrogenic inducing biomaterial tacking advance on the synergy between alginate matrix and Co+2 ions without employing other expensive growth factors such as TGFbs or BMPs. Cells were cultured up to 3 weeks into alginate beads at different Ca/Co ratio, Calcein/Ethidium assay was performed to evaluate cell viability, light, and transmis- sion electron microscopy were carried out to check the cells behaviour. The expression of chondrogenic markers such as sox9, collagen type II, and versican was investigated by Real Time PCR. The expression of hif1mRNA was investigated to check the capability of Co+2 ions to induce a chemical hypoxia. Results showed an high cell viability at high Ca/Co ratio value of alginate beads. Real Time PCR data reveal a different cells behaviour on chondrogenic marker expression. In conclusion, the synergic effect of alginate and Co+2 ions can represent a valid strategy for chondrogenic differentiation of stem cells.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
The electrical and magnetic properties of magnetite at the low temperature phase transition
Creators: name: Cheeke, John David Nicholas
Publisher: name: University of British Columbia
Year: 2011

description: The electrical and magnetic properties of magnetite from 100-300°K have been studied. Specimens were obtained from natural crystals of local origin and fabricated in the form of rectangular bars. When this was not possible, due to excessive cracks in the crystal, the electrical properties of the resulting irregularly shaped disc were measured by use of the Van der Pauw theorem. Observation of the temperature variation of the resistivity showed that the resistivity increased as the temperature was decreased and that it increased by a factor 24 over a 10°K temperature interval when the specimen was cooled below 115°K. This phenomenon is related to an order-disorder transition at this temperature, in which the crystalline symmetry changes from cubic to orthorhombic. One specimen did not show the resistivity transition, probably due to excessive impurity content, which would prevent ordering from occurring. The results are explained qualitatively by the Verwey model, which postulates a conduction mechanism involving the jumping of electrons between octahedral sites of the Fe₃O₄ unit cell, as opposed to the conventional band type of conduction. An attempt was made to measure the Hall mobility of the specimens, but a Hall voltage was not detected within the sensitivity of the apparatus. An upper limit of 1 cm²/volt-sec. for the mobility was established. A negative magnetoresistance effect was observed in both specimens and was measured as a function of temperature for both transverse and longitudinal magnetic fields. A pronounced minimum at the transition temperature was observed for one specimen, while the other showed no change here. The AC permeability was observed over the transition region and again a sharp decrease was observed on cooling through the transition. Normal induction curves were obtained for the specimen at various fixed temperatures from the permeability data, from which it was deduced that the specimen was much harder to saturate below the transition. The permeability on warming was found to be independent of the magnetic state of the sample while cooling through the transition, and it was again observed that one crystal did not undergo the phase transition at 115°K.
On the evolution of mean motion resonances through stochastic forcing: Fast and slow libration modes and the origin of HD128311
Creators: name: Rein, Hanno
name: Papaloizou, John C. B.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Aims. We clarify the response of extrasolar planetary systems in a 2:1 mean motion commensurability with masses ranging from the super Jovian range to the terrestrial range to stochastic forcing that could result from protoplanetary disk turbulence. The behaviour of the different libration modes for a wide range of system parameters and stochastic forcing magnitudes is investigated. The growth of libration amplitudes is parameterized as a function of the relevant physical parameters. The results are applied to provide an explanation of the configuration of the HD128311 system. Methods. We first develop an analytic model from first principles without making the assumption that both eccentricities are small. We also perform numerical N-body simulations with additional stochastic forcing terms to represent the effects of putative disk turbulence. Results. Systems are quickly destabilized by large magnitudes of stochastic forcing but some stability is imparted should systems undergo a net orbital migration. The slow mode, which mostly corresponds to motion of the angle between the apsidal lines of the two planets, is converted to circulation more readily than the fast mode which is associated with oscillations of the semi-major axes. This mode is also vulnerable to the attainment of small eccentricities which causes oscillations between periods of libration and circulation. Conclusions. Stochastic forcing due to disk turbulence may have played a role in shaping the configurations of observed systems in mean motion resonance. It naturally provides a mechanism for accounting for the HD128311 system.
description: 15 pages, 8 figures, added discussion in h and k coordinates, recommended for publication
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ¸ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð²Ð¸Ð·ÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÑÐ¾Ð´ÐµÑÐ¶Ð¸Ð¼Ð¾Ð³Ð¾ Ð´Ð»Ñ ÑÐ»ÑÑÑÐµÐ½Ð¸Ñ ÑÐ·Ð°Ð±Ð¸Ð»Ð¸ÑÐ¸ Ð²ÐµÐ±-ÑÐµÑÑÑÑÐ¾Ð² Ñ Ð¼ÑÐ·ÑÐºÐ°Ð»ÑÐ½Ð¾Ð¹ ÑÐµÐ¼Ð°ÑÐ¸ÐºÐ¾Ð¹
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: ÐÐµÐ»Ð¾Ð²Ð°, ÐÐ°ÑÐ°Ð»ÑÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÐÐ½ÑÐµÑÐ½ÐµÑ
Ð²ÐµÐ±-ÑÐµÑÑÑÑÑ
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description: The object of the study is method of creation of visual content for usability improvement for musical theme web-resources. Objective - to create a website of music academy on the basis of the developed technique . In the process was conducted the analogs review of music academy sites, the advantages and disadvantages of filling the visual content was found. The analogues of methods of creation of visual content on sites were considered. As a result of the study it was concluded that there is the lack of information on this direction and the lack of methods for music sites. My own version of methods was developed and on the basis of its site of music academy was established. Efficiency of technique was defined by conducting a survey and questionnaires of target audience of web site.