cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Regulation of Chondrogenesis in Human Mesenchymal Stem Cells by Cartilage Extracellular Matrix and Therapeutic Applications
Creators: Li, Ang
Publisher: name: Columbia University
Year: 2018
Subjects: Biomedical engineering
Chondrogenesis
Cartilage
Extracellular matrix

description: Cartilage has limited intrinsic healing potential upon injury, due to the low cell density and the lack of blood supply. Degenerative disease of the cartilage, such as osteoarthritis (OA), is challenging to treat without clear mechanistic understandings of cartilage development. With over 90% of the cartilage tissue occupied by extracellular matrix (ECM), understanding the cellular and molecular effects of cartilage ECM on chondrogenesis and chondrocyte behavior is crucial for therapeutic development. The focus of this work is to study the regulation of chondrogenesis and hypertrophic maturation of human mesenchymal stem cells (MSCs) by cartilage ECM in the context of potential therapeutic applications.
      To study the cartilage ECM, we created a decellularized ECM digest from native porcine cartilage and examined its effects on MSCs. Since native cartilage ECM maintains chondrocyte homeostasis without progressing to hypertrophic degeneration, we hypothesized that the decellularized ECM would promote MSC chondrogenesis and inhibit hypertrophy. Indeed, we showed that ECM promoted MSC chondrogenesis and matrix production, and inhibited hypertrophy and endochondral ossification. The chondrogenic effect was shown to potentially involve the PI3K-Akt-Foxo1 and Hif1 pathways. By recapitulating the activated Hif1 pathway, roxadustat, a small molecule stabilizer of Hif, was able to reproduce the chondrogenic and anti-hypertrophic effects of the cartilage ECM. It also reduced the expression of matrix metalloproteases (MMPs) in MSCs, healthy chondrocytes, and OA chondrocytes, and alleviated matrix degradation in bovine cartilage explants.
      We also attempted to identify ECM components that display chondrogenic properties. Collagen XI, a minor component of articular cartilage, was shown to promote cartilage matrix formation in MSCs and healthy chondrocytes, and to reduce matrix degradation in bovine cartilage explants.
      Taken together, this study reveals the dual roles of cartilage ECM in promoting chondrogenesis and matrix production and inhibiting cartilage hypertrophy. Importantly, small molecule drugs that recapitulate the signaling pathways of ECM regulation, and collagen XI, a component of the ECM, may serve as leads for further therapeutic development for cartilage injury and degenerative disease.
title: Преступления в сфере предпринимательской и иной экономической деятельности. Уголовная ответственность за легализацию (отмывание) преступных доходов
title: Учебное пособие
titleType: Subtitle
Creators: name: Жариков Ю.С.
Publisher: name: Ай Пи Ар Медиа
Year: 2019

description: Учебное пособие посвящено вопросам уголовной ответственности за легализацию денежных средств и иного имущества, приобретенных преступным путем. Подготовлено в соответствии с требованиями Федерального государственного образовательного стандарта высшего образования по направлению подготовки 40.04.01 «Юриспруденция» и может использоваться студентами, обучающимися по магистерским программам «Уголовное право, криминология, уголовно-исполнительное право»; «Предупреждение экономической преступности уголовно-правовыми средствами»; «Уголовно-правовая защита экономики и предпринимательства» и другим аналогичным программам, при изучении дисциплин «Теоретические основы применения уголовного законодательства», «Преступления в сфере предпринимательской и иной экономической деятельности» и «Должностные преступления в сфере экономической деятельности».
Possible interpretations of the $P_c(4312)$, $P_c(4440)$, and $P_c(4457)$
Creators: name: Chen, Hua-Xing
name: Chen, Wei
name: Zhu, Shi-Lin
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Based on our previous QCD sum rule studies on hidden-charm pentaquark states, we discuss possible interpretations of the $P_c(4312)$, $P_c(4440)$, and $P_c(4457)$, which were recently observed by LHCb. Our results suggest that the $P_c(4312)$ can be well interpreted as the $[Σ_c^{++} \bar D^-]$ bound state with $J^P = 1/2^-$, while the $P_c(4440)$ and $P_c(4457)$ can be interpreted as the $[Σ_c^{+} \bar D^0]$ bound state with $J^P = 1/2^-$, the $[Σ_c^{*++} \bar D^{-}]$ and $[Σ_c^{+} \bar D^{*0}]$ bound states with $J^P = 3/2^-$, or the $[Σ_c^{*+} \bar D^{*0}]$ bound state with $J^P = 5/2^-$. We propose to measure their spin-parity quantum numbers to verify these assignments.
description: 5 pages, 1 figure, 1 table, revised version published in PRD
Evaluation of Methods for Semantic Segmentation of Endoscopic Images
Creators: name: Bopp, Bastian
name: Scheikl, Paul Maria
name: Kunz, Christian
name: Mathis-Ullrich, Franziska
Publisher: name: Karlsruhe
Year: 2019
Subjects: robot-assisted surgery
computer vision
semantic image segmentation
deep learning

description: We examined multiple semantic segmentation methods, which consider the information contained in endoscopic images at different levels of abstraction in order to predict semantic segmentation masks. These segmentations can be used to obtain position information of surgical instruments in endoscopic images, which is the foundation for many computer assisted systems, such as automatic instrument tracking systems. The methods in this paper were examined and compared in regard to their accuracy, effort to create the data set, and inference time. Of all the investigated approaches, the LinkNet34 encoder-decoder network scored best, achieving an Intersection over Union score of 0.838 with an inference time of 30.25 ms on a 640 x 480 pixel input image with a NVIDIA GTX 1070Ti GPU.
title: Modellbasierte Spezifikation von RESTful SOA auf Basis von Geschäftsprozessmodellen
Creators: name: Wolf, Matthias
Publisher: name: Institut für Wirtschaftsinformatik
Year: 2012
Subjects: subject: 33
subject: 000

description: Der Einsatz von Web-Services auf Basis des Architekturstils REpresentational State Transfer (REST) gewinnt zur Realisierung service-orientierter Architekturen (SOA) immer mehr an Bedeutung. Im unternehmerischen Umfeld dienen SOAs häufig der Automatisierung flexibler Geschäftsprozesse. Mit dem zunehmenden Einsatz von RESTful Web-Services zur Geschäfts-prozessautomatisierung wächst auch der Bedarf nach einem Ansatz zur Spezifikation einer RESTful SOA aus fachlichen Anforderungen. Diese werden häufig mit Geschäftsprozessmodellen analysiert, gestaltet und dokumentiert. Der vorliegende Beitrag erarbeitet einen dreistufigen Entwicklungsprozess für die modellbasierte Ableitung von RESTful SOA-Spezifikationen aus Geschäftsprozessmodellen.
description: Multikonferenz Wirtschaftsinformatik 2012 : Tagungsband der MKWI 2012
Optimal quantum pump in the presence of a superconducting lead
Creators: name: Wang, Baigeng
name: Wang, Jian
Publisher: name: arXiv
Year: 2002
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We investigate the parametric pumping of a hybrid structure consisting of a normal quantum dot, a normal lead and a superconducting lead. Using the time dependent scattering matrix theory, we have derived a general expression for the pumped electric current and heat current. We have also derived the relationship among the instantaneous pumped heat current, electric current, and shot noise. This gives a lower bound for the pumped heat current in the hybrid system similar to that of the normal case obtained by Avron et al.
Celtis africana Burm. f.
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Cannabaceae
Celtis
Celtis africana

description: Celtis africana Burm.f.  —
Habit: Tree.
Habitat: LMWF, LMDF; up to 2 400 m. Distribution: II.
 Voucher: Mount Kenya, Alt. 1 981 m, Rammell 1051 (EA).
References: Fries & Fries (1924), Bussmann (1993, 1994), Bussmann & Beck (1995a).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 50, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
How to make a triangulation of S^3 polytopal
Creators: name: King, Simon A.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 52B11; 57M25, 57Q15, 52B22

description: We introduce a numerical isomorphism invariant p(T) for any triangulation T of S^3. Although its definition is purely topological (inspired by the bridge number of knots), p(T) reflects the geometric properties of T. Specifically, if T is polytopal or shellable then p(T) is `small' in the sense that we obtain a linear upper bound for p(T) in the number n=n(T) of tetrahedra of T. Conversely, if p(T) is `small' then T is `almost' polytopal, since we show how to transform T into a polytopal triangulation by O((p(T))^2) local subdivisions. The minimal number of local subdivisions needed to transform T into a polytopal triangulation is at least $\frac{p(T)}{3n}-n-2$. Using our previous results [math.GT/0007032], we obtain a general upper bound for p(T) exponential in n^2. We prove here by explicit constructions that there is no general subexponential upper bound for p(T) in n. Thus, we obtain triangulations that are `very far' from being polytopal. Our results yield a recognition algorithm for S^3 that is conceptually simpler, though somewhat slower, as the famous Rubinstein-Thompson algorithm.
description: 24 pages, 17 figures. Final version
Constraints on ultra-low-frequency gravitational waves with statistics of pulsar spin-down rates
Creators: name: Kumamoto, Hiroki
name: Imasato, Yuya
name: Yonemaru, Naoyuki
name: Takahashi, Keitaro
name: Kuroyanagi, Sachiko
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We probe ultra-low-frequency gravitational waves (GWs) with statistics of spin-down rates of milli-second pulsars (MSPs) by a method proposed in our prevous work (Yonemaru et al. 2016). The considered frequency range is $10^{-12}{\rm Hz} \lesssim f_{\rm GW} \lesssim 10^{-10}$Hz, which cannot be accessed by the conventional pulsar timing array. The effect of such low-frequency GWs appears as a bias to spin-down rates which has a quadrupole pattern in the sky. We use the skewness of the spin-down rate distribution and the number of MSPs with negative spin-down rates to search for the bias induced by GWs. Applying this method to 149 MSPs selected from the ATNF pulsar catalog, we derive upper bounds on the time derivative of the GW amplitudes of $\dot{h} < 6.2 \times 10^{-18}~{\rm sec}^{-1}$ and $\dot{h} < 8.1 \times 10^{-18}~{\rm sec}^{-1}$ in the directions of the Galactic Center and M87, respectively. Approximating the GW amplitude as $\dot{h} \sim 2 πf_{\rm GW} h$, the bounds translate into $h < 3 \times 10^{-9}$ and $h < 4 \times 10^{-9}$, respectively, for $f_{\rm GW} = 1/(100~{\rm yr})$. Finally, we give the implications to possible super-massive black hole binaries at these sites.
description: 6pages, 10figures
Antiteuchus sepulcralis Fabricius 1803
Creators: name: Castro-Huertas, Valentina
name: Schwertner, Cristiano F.
name: Fernández, Fernando
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Antiteuchus
Antiteuchus sepulcralis

description: Antiteuchus sepulcralis (Fabricius, 1803)
Examined material. AMAZONAS. PNN Amacayacu, Zona varzea, malaise, 3 feb 1998, F. Alvarado / IAvH-E 0 5063 (1m, IAvH); Matamata, malaise, 1 feb 1989, F. Fernández / IAvH-E 0 5052, IAvH-E 0 5053 (2m, IAvH); Puerto Nariño, sobre el río Loteroyacú, 600m, 13 dec 1991, M.L. Baena / IAvH-E 0 5058, IAvH-E 0 5059 (1m, 1h, IAvH). META. Mesetas, Parque del pueblo, 3°22´41"N, 74°2´41"W, 800m, 22 nov 1987, F. Fernández / IAvH-E 0 5076 (1h, IAvH); PNN La Macarena, Vista Hermosa, Piñalito, alrededores de la casa, 2°58´30"N, 73°39´48"W, 400m, 3 jan 1989, F. Fernández / IAvH-E 0 5074 (1h, IAvH).
Comments. First record of this species for Colombia. This species has been recorded for Trinidad and Tobago, Venezuela, French Guiana, Brazil and Bolivia (Becker & Grazia 1977; Fernandes & Grazia 2006).
description: Published as part of Castro-Huertas, Valentina, Schwertner, Cristiano F. & Fernández, Fernando, 2015, New records of stink bugs (Hemiptera: Pentatomidae) from Colombia, pp. 553-566 in Zootaxa 3973 (3) on page 556, DOI: 10.11646/zootaxa.3973.3.9, http://zenodo.org/record/236474
Integrated analysis of lncRNA and mRNA repertoires in Marek’s disease infected spleens identifies genes relevant to resistance
Creators: name: You, Zhen
name: Zhang, Qinghe
name: Liu, Changjun
name: Song, Jiuzhou
name: Yang, Ning
name: Lian, Ling
Publisher: name: Springer Nature
Year: 2019
Subjects: Chicken
Long noncoding RNA
Marek’s disease
MD resistance

description: Marek’s disease virus (MDV) is an oncogenic herpesvirus that can cause T-cell lymphomas in chicken. Long noncoding RNA (lncRNA) is strongly associated with various cancers and many other diseases. In chickens, lncRNAs have not been comprehensively identified. Here, we profiled mRNA and lncRNA repertoires in three groups of spleens from MDV-infected and non-infected chickens, including seven tumorous spleens (TS) from MDV-infected chickens, five spleens from the survivors (SS) without lesions after MDV infection, and five spleens from noninfected chickens (NS), to explore the underlying mechanism of host resistance in Marek’s disease (MD).
From reclamation to relinquishment : is this an achievable goal in British Columbia?
Creators: name: Sanders, J.
name: Murphy, M.
Publisher: name: The University of British Columbia
Year: 2020

description: Transitioning a mine from reclamation to relinquishment is a significant challenge. The International Council for Metals and Mining (ICMM) defines relinquishment as “the transition of ownership and residual liability to the jurisdictional authority or a third party”. But, is mine relinquishment achievable within British Columbia (BC)? Are there clear regulatory mechanisms that support a pathway from progressive reclamation to relinquishment? Are all mine closure domains including tailings facilities possible to relinquish? And, why is assessment of post-closure residual risk crucial regardless of the presence of a clear regulatory mechanism in place? This paper discusses some of these key challenges on the pathway from progressive reclamation towards potential mine relinquishment. We focus on tailings facilities as these assets typically represent the greatest post-closure residual risk for a mine operator. The paper begins with a discussion on the current mine relinquishment regulatory framework in BC compared to other global policy examples. We then explore aspects of a mine relinquishment framework in the context of landform design and provide potential completion criteria to support risk assessment and closure objectives. We conclude with a discussion on risk-based Front-End Loading (FEL) practices that are needed for integrated closure planning regardless of a whether a mechanism for relinquishment is in place.
Celtis gomphophylla Baker
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Cannabaceae
Celtis
Celtis gomphophylla

description: Celtis gomphophylla Baker  —
Habit: Tree.
Habitat: LMWF; up to 2 000 m. Distribution: II.
 Voucher: Upper Imenti Forest, Alt. 1 740 m, 28–29 Jun. 1974, Faden & Faden 74/908 (EA, WAG).
Reference: Fries & Fries (1924).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 50, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
title: DeCREE: Eine Domänenspezifische Sprache zur Modellierung von Choreography-First Szenarien
Creators: name: Gringel, Philipp
name: Gudenkauf, Stefan
name: Kruse, Steffen
Publisher: name: Institut für Wirtschaftsinformatik
Year: 2012
Subjects: subject: 33
subject: 000

description: Die Choreografie-Diagramme der BPMN 2.0 erlauben die Modellierung von Interaktionsprotokollen zwischen verschiedenen Teilnehmern. Es sinnvoll, die jeweiligen Zuständigkeiten der Teilnehmer explizit mit zu modellieren. Herausforderungen sind die strikte Einhaltung der relevanten BPMN-Untermenge zur Erhaltung von Konformität und Interoperabilität, sowie die Handhabung der Zuständigkeiten als Modellelemente erster Klasse um Interaktionsprotokolle auf fachlich höherer Ebene validieren zu können. Mit dem vorgeschlagenen Choreography-First Ansatz und der Modellierungssprache DeCREE bewältigen wir diese Herausforderungen. Das Metamodell von DeCREE umfasst sowohl eine BPMN-Untermenge als auch RACI-Zuständigkeiten. Als Beleg für die Machbarkeit stellen wir eine Implementierung der DSL auf Basis des Xtext Language Frameworks vor.
description: Multikonferenz Wirtschaftsinformatik 2012 : Tagungsband der MKWI 2012
Cell maps on the human genome
Creators: name: Cherniak, Christopher
name: Rodriguez-Esteban, Raul
Publisher: name: Springer Nature
Year: 2019
Subjects: Genome
Somatotopic map
Homunculus
“Cellunculus”
Organelle-specific gene
Connection optimization

description: We have previously described evidence for a statistically significant, global, supra-chromosomal representation of the human body that appears to stretch over the entire genome. Here, we extend the genome mapping model, zooming down to the typical individual animal cell. Its cellular organization appears to be significantly mapped onto the human genome: Evidence is reported for a “cellunculus” — on the model of a homunculus, on the H. sapiens genome.
title: Flexible Controls for Compliance in Catastrophe Management Processes
Creators: name: Kittel, Kai
name: Sackmann, Stefan
Publisher: name: Institut für Wirtschaftsinformatik
Year: 2012
Subjects: subject: 33
subject: 000

description: Managing business processes is becoming increasingly flexible on both the conceptual and the technical level. Flexibility opens up new scopes of application. This contribution focuses on improving resilience of basic services (e.g., water supply) and rescue processes (e.g., firefighting) for catastrophic events by BPM approaches. However, flexibility is only seen as a necessary, but not sufficient condition for managing catastrophic events efficiently. Moreover, process flexibility has to be accompanied by comprehensive access to and processing of public as well as private information. Therefore, validating compliance is a still disregarded but crucial aspect. In this contribution, a model-based approach aiming at an automated adaptation of controls to changes of flexible processes is presented and discussed. As result, a future research agenda with concrete research topics is determined.
description: Multikonferenz Wirtschaftsinformatik 2012 : Tagungsband der MKWI 2012
On gauge-equivalent formulations of N=4 SKdV hierarchy
Creators: name: Ivanov, E.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We point out that the N=4 supersymmetric KdV hierarchy, when written through the prepotentials of the bosonic chiral and antichiral N=2 supercurrents, exhibits a freedom related to the possibility to choose different gauges for the prepotentials. In particular, this implies that the Lax operator for the N=4 SKdV system and the associated realization of N=4 supersymmetry obtained in solv-int/9802003 are reduced to the previously known ones. We give the prepotential form of the `small' N=4 superconformal algebra, the second hamiltonian structure algebra of the N=4 SKdV hierarchy, for two choices of gauge.
description: 7 pages, LaTeX
Additional file 1 of Improving the accuracy of genomic prediction for meat quality traits using whole genome sequence data in pigs
Creators: name: Zhuang, Zhanwei
name: Wu, Jie
name: Qiu, Yibin
name: Ruan, Donglin
name: Ding, Rongrong
name: Xu, Cineng
name: Zhou, Shenping
name: Zhang, Yuling
name: Liu, Yiyi
name: Ma, Fucai
name: Yang, Jifei
name: Sun, Ying
name: Zheng, Enqin
name: Yang, Ming
name: Cai, Gengyuan
name: Yang, Jie
name: Wu, Zhenfang
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Summary statistics of meat quality traits in pigs.
Trema orientalis (L.) Blume
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Cannabaceae
Trema
Trema orientalis

description: Trema orientalis (L.) Blume  —
Habit: Shrub or small tree.
Habitat: LMWF; up to 2 100 m. Distribution: I.
Voucher: N/A.
Reference: Fries & Fries (1924).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 50, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
title: Eine empirische Studie zur strukturellen Komplexität konzeptioneller Modelle – Grundlegung eines effizienten Ansatzes zur strukturellen Modellanalyse
Creators: name: Breuker, Dominic
name: Dietrich, Hanns-Alexander
name: Püster, Johannes
name: Steinhorst, Matthias
name: Becker, Jörg
name: Delfmann, Patrick
Publisher: name: Institut für Wirtschaftsinformatik
Year: 2012
Subjects: subject: 33
subject: 000

description: Für die Analyse konzeptioneller Informationsmodelle existiert eine Vielzahl von Verfahren, die für eine bestimmte Modellierungssprache oder Anwendungsdomäne entwickelt wurden und abgegrenzte Analysezwecke unterstützen. Häufig besteht eine Teilaufgabe der Analyseverfahren in der Identifikation struktureller Modellmuster. Für dieses als Subgraphisomorphie bekannte Problem existieren effiziente, allgemein anwendbare Algorithmen, die bestimmte topologische Eigenschaften der zugrundeliegenden Graphen voraussetzen. Dieser Beitrag präsentiert die Ergebnisse der Untersuchung von 3000 Informationsmodellen und demonstriert, dass die meisten dieser Modelle entsprechende Eigenschaften aufweisen. Er präsentiert eine empirische Studie für die Entwicklung einer allgemein anwendbaren Analysemethode, die in viele Spezialentwicklungen integriert werden kann.
description: Multikonferenz Wirtschaftsinformatik 2012 : Tagungsband der MKWI 2012
title: Уголовная политика. Взаимодействие субъектов правоохранительной системы в процессе противодействия преступности (правовые и организационные аспекты)
title: Учебное пособие для магистрантов
titleType: Subtitle
Creators: name: Жариков Ю.С.
Publisher: name: Ай Пи Ар Медиа
Year: 2020

description: Учебное пособие посвящено изучению наиболее значимых направлений и мер противодействия преступности, анализу сущности криминологического мониторинга и механизма формирования его системы. В нем описываются современные подходы к пониманию и практической организации взаимодействия различных правоохранительных органов. Рассматриваются вопросы правового регулирования взаимодействия субъектов, осуществляющих противодействие преступности на федеральном и региональном уровнях. Подготовлено в соответствии с Федеральным государственным образовательным стандартом высшего образования по направлению подготовки магистратуры 40.04.01 «Юриспруденция» и будет полезно при изучении дисциплин «Криминология» и «Уголовная политика». Издание предназначено для преподавателей, аспирантов, магистрантов, студентов юридических вузов, может быть полезно практическим сотрудникам правоохранительных органов, занимающимся вопросами предупреждения преступности.
title: Zur Identifikation von Strukturanalogien in Prozessmodellen
Creators: name: Walter, Jürgen
name: Fettke, Peter
name: Loos, Peter
Publisher: name: Institut für Wirtschaftsinformatik
Year: 2012
Subjects: subject: 33
subject: 000

description: Geschäftsprozessmodelle haben einen bedeutenden Stellenwert für die Modellierung betrieblicher Informationssysteme. Mit der immer größer werdenden Verbreitung nimmt auch die Komplexität solcher Modelle zu. Oft umfassen sie mehrere hunderte oder tausende Elemente, nicht selten mit erheblichen Redundanzen. Um eine Senkung dieses Umfangs zu erreichen, wurde in der Literatur auf die Verwendung von Analogien verwiesen. Da diese jedoch bisher nur für Datenmodelle definiert wurden, werden in diesem Beitrag einige Definitionen im Kontext von Prozessmodellen gegeben und entsprechende Maße zur Analogieberechnung vorgestellt sowie deren Anwendungspotentiale aufgezeigt.
description: Multikonferenz Wirtschaftsinformatik 2012 : Tagungsband der MKWI 2012
Dorstenia afromontana R. E. Fr.
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Moraceae
Dorstenia
Dorstenia afromontana

description: Dorstenia afromontana R.E.Fr.  —
Habit: Herb.
Habitat: LMWF, LMDF; 1 900–2 600 m. Distribution: IIIa.
 Voucher: Naro Moru Track, Alt. 2 477 m, 11 Jun. 2010, Kirika et al. KMK76 (EA).
References: Fries & Fries (1924), Berg & Hijman (1989), Agnew (2013).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 50, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
A balanced game: chicken macrophage response to ALV-J infection
Creators: name: Feng, Min
name: Xie, Tingting
name: Li, Yuanfang
name: Zhang, Nan
name: Lu, Qiuyuan
name: Zhou, Yaohong
name: Shi, Meiqing
name: Sun, Jingchen
name: Zhang, Xiquan
Publisher: name: Springer Nature
Year: 2019

description: Avian leukosis virus subgroup J (ALV-J) infection can cause tumors and immunosuppression in infected chickens. Macrophages play a central role in host defense against invading pathogens. In this study, we discovered an interesting phenomenon: ALV-J replication is weakened from 3 hours post-infection (hpi) to 36 hpi, which was verified using Western blotting and RT-PCR. To further investigate the interaction between ALV-J and macrophages, transcriptome analysis was performed to analyze the host genes’ function in chicken primary monocyte-derived macrophages (MDM). Compared to the uninfected control, 624 up-regulated differentially expressed genes (DEG) and 341 down-regulated DEG at 3 hpi, and 174 up-regulated DEG and 87 down-regulated DEG at 36 hpi were identified in chicken MDM, respectively. ALV-J infection induced strong innate immune responses in chicken MDM at 3 hpi, instead of 36 hpi, according to the analysis results of Gene Ontology and KEGG pathway. Importantly, the host factors, such as up-regulated MIP-3α, IL-1β, iNOS, K60, IRG1, CH25H, NFKBIZ, lysozyme and OASL were involved in the host defense response during the course of ALV-J infection. On the contrary, up-regulated EX-FABP, IL4I1, COX-2, NFKBIA, TNFAIP3 and the Jak STAT pathway inhibitors including CISH, SOCS1 and SOCS3 are beneficial to ALV-J survival in chicken macrophages. We speculated that ALV-J tropism for macrophages helps to establish a latent infection in chicken MDM from 6 to 36 hpi. The present study provides a comprehensive view of the interactions between macrophages and ALV-J. It suggests the mechanisms of defense of chicken macrophages against ALV-J invasion and how ALV-J escape the host innate immune responses.
Phase transition of the Si(111)-4x1-In surface reconstruction investigated by electron transport measurements
Creators: name: Uchihashi, Takashi
name: Ramsperger, Urs
Publisher: name: arXiv
Year: 2002
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We measure the electron conductivity of the surface states and the subsurface space charge layer originating from the Si(111)-4x1-In reconstruction as a function of temperature. The conductivity of the surface states drops sharply around 130 K with decreasing temperature, revealing a metal-insulator phase transition of the surface reconstruction. In contrast, the influence of the phase transition on the conductivity of the space charge layer is limited to temperatures above 60 K. This means that the surface Fermi level remains strongly pinned despite the phase transition, indicating the presence of free carriers in the surface states down to rather low temperatures.
description: 10 pages, 3 figures, submitted to Surface Science
The meromorphic non-integrability of the planar three-body problem
Creators: name: Tsygvintsev, Alexei
Publisher: name: arXiv
Year: 2000
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37K10

description: We study the planar three-body problem and prove the absence of a complete set of complex meromorphic first integrals in a neighborhood of the Lagrangian solution.
description: 4 pages, French
Benthic invertebrate community recovery in a remediated stream
Creators: name: Batchelar, Katharina
name: Stecko, Pierre
name: Hughes, Colleen
Publisher: name: The University of British Columbia
Year: 2020

description: A foundational failure of the perimeter embankment of the Mount Polley Mine Tailings Storage Facility (TSF) on August 4th 2014 resulted in a breach that released approximately 25 million cubic meters of debris (water and solids that consisted of tailings, construction materials, and scoured sediment and soil). The debris flowed along the entire length of Hazeltine Creek, scouring native materials and depositing TSF material in the creek channel. A first phase of channel remediation in Hazeltine Creek was completed in 2015, and a second phase which incorporated natural geomorphological and fish habitat values was completed in 2016 and 2017. Benthic invertebrate community monitoring was completed most recently in these remediated areas in 2017 and 2018. This monitoring documented rapid recolonization on the basis of organism densities that were similar to pre-breach in some areas, including colonization by sensitive EPT taxa. A number of differences relative to pre-breach remained, indicating that the community was still recovering from physical disturbances associated with the remediation work (including the influences of ongoing work on downstream areas). These included lower organism density in some areas, lower taxon richness, and a community that was dominated by early successional or tolerant taxon groups.
Burgers' Flows as Markovian Diffusion Processes
Creators: name: Garbaczewski, P.
name: Kondrat, G.
name: Olkiewicz, R.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Condensed Matter (cond-mat)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences

description: We analyze the unforced and deterministically forced Burgers equation in the framework of the (diffusive) interpolating dynamics that solves the so-called Schrödinger boundary data problem for the random matter transport. This entails an exploration of the consistency conditions that allow to interpret dispersion of passive contaminants in the Burgers flow as a Markovian diffusion process. In general, the usage of a continuity equation $\partial_tρ=-\nabla (\vec{v}ρ)$, where $\vec{v}=\vec{v}(\vec{x},t)$ stands for the Burgers field and $ρ$ is the density of transported matter, is at variance with the explicit diffusion scenario. Under these circumstances, we give a complete characterisation of the diffusive transport that is governed by Burgers velocity fields. The result extends both to the approximate description of the transport driven by an incompressible fluid and to motions in an infinitely compressible medium. Also, in conjunction with the Born statistical postulate in quantum theory, it pertains to the probabilistic (diffusive) counterpart of the Schrödinger picture quantum dynamics.
description: Latex file
title: Empirical Support for the Usefulness of Personalized Process Model Views
Creators: name: Koschmider, Agnes
name: Reijers, Hajo
name: Dijman, Remco
Publisher: name: Institut für Wirtschaftsinformatik
Year: 2012
Subjects: subject: 33
subject: 000

description: Business process models are a valued asset to support the communication between a range of business professionals. While it has been common to display process models in the same way as they are created, recent approaches support the use of personalized views on such models. This paper presents one of the first empirical studies that demonstrate the importance of model adjustment to end user preferences. In particular, the results suggest that end users can inspect a process model in accordance with their preferred style of granularity (modular or flattened) without any negative effects on their performance in making sense of such a model. This is a valuable result since it allows for a “separation of concerns”, i.e. automatic tools can take over part of the modeler's task with respect to addressing end user needs.
description: Multikonferenz Wirtschaftsinformatik 2012 : Tagungsband der MKWI 2012
Low Temperature Symmetry of Pyrochlore Oxide Cd2Re2O7
Creators: name: Yamaura, Jun-Ichi
name: Hiroi, Zenji
Publisher: name: arXiv
Year: 2002
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report the X-ray study for the pyrochlore oxide Cd2Re2O7. Two symmetry-lowering structural transitions were observed at Ts1=200K and Ts2=120K. The former is of the second order from the ideal cubic pyrochlore structure with space group Fd-3m to a tetragonally distorted structure with I-4m2, while the latter is of the first order likely to another tetragonal space group I4122. We discuss the feature of the lattice deformation.
description: 4 pages, 4 figures
title: Vorwort zur Teilkonferenz [8]: Kommunikations- und Kooperationssysteme
Creators: name: Koch, Michael
Publisher: name: Institut für Wirtschaftsinformatik
Year: 2012
Subjects: subject: 33
subject: 000

description: Multikonferenz Wirtschaftsinformatik 2012 : Tagungsband der MKWI 2012
Restrictions on negative energy density in a curved spacetime
Creators: name: Song, Dae-Yup
Publisher: name: arXiv
Year: 1997
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Recently a restriction ("quantum inequality-type relation") on the (renormalized) energy density measured by a static observer in a "globally static" (ultrastatic) spacetime has been formulated by Pfenning and Ford for the minimally coupled scalar field, in the extension of quantum inequality-type relation on flat spacetime of Ford and Roman. They found negative lower bounds for the line integrals of energy density multiplied by a sampling (weighting) function, and explicitly evaluate them for some specific spacetimes. In this paper, we study the lower bound on spacetimes whose spacelike hypersurfaces are compact and without boundary. In the short "sampling time" limit, the bound has asymptotic expansion. Although the expansion can not be represented by locally invariant quantities in general due to the nonlocal nature of the integral, we explicitly evaluate the dominant terms in the limit in terms of the invariant quantities. We also make an estimate for the bound in the long sampling time limit.
description: LaTex, 23 Pages
The Ultrasensitivity of Living Polymers
Creators: name: O'Shaughnessy, Ben
name: Vavylonis, Dimitrios
Publisher: name: arXiv
Year: 2002
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Synthetic and biological living polymers are self-assembling chains whose chain length distributions (CLDs) are dynamic. We show these dynamics are ultrasensitive: even a small perturbation (e.g. temperature jump) non-linearly distorts the CLD, eliminating or massively augmenting short chains. The origin is fast relaxation of mass variables (mean chain length, monomer concentration) which perturbs CLD shape variables before these can relax via slow chain growth rate fluctuations. Viscosity relaxation predictions agree with experiments on the best-studied synthetic system, alpha-methylstyrene.
description: 4 pages, submitted to Phys. Rev. Lett
Development of a recombinant Newcastle disease virus-vectored vaccine for infectious bronchitis virus variant strains circulating in Egypt
Creators: name: Abozeid, Hassanein H.
name: Paldurai, Anandan
name: Varghese, Berin P.
name: Khattar, Sunil K.
name: Afifi, Manal A.
name: Zouelfakkar, Sahar
name: El-Deeb, Ayman H.
name: El-Kady, Magdy F.
name: Samal, Siba K.
Publisher: name: Springer Nature
Year: 2019

description: Infectious bronchitis virus (IBV) causes a major disease problem for the poultry industry worldwide. The currently used live-attenuated vaccines have the tendency to mutate and/or recombine with circulating field strains resulting in the emergence of vaccine-derived variant viruses. In order to circumvent these issues, and to develop a vaccine that is more relevant to Egypt and its neighboring countries, a recombinant avirulent Newcastle disease virus (rNDV) strain LaSota was constructed to express the codon-optimized S glycoprotein of the Egyptian IBV variant strain IBV/Ck/EG/CU/4/2014 belonging to GI-23 lineage, that is prevalent in Egypt and in the Middle East. A wild type and two modified versions of the IBV S protein were expressed individually by rNDV. A high level of S protein expression was detected in vitro by Western blot and immunofluorescence analyses. All rNDV-vectored IBV vaccine candidates were genetically stable, slightly attenuated and showed growth patterns comparable to that of parental rLaSota virus. Single-dose vaccination of 1-day-old SPF White Leghorn chicks with the rNDVs expressing IBV S protein provided significant protection against clinical disease after IBV challenge but did not show reduction in tracheal viral shedding. Single-dose vaccination also provided complete protection against virulent NDV challenge. However, prime-boost vaccination using rNDV expressing the wild type IBV S protein provided better protection, after IBV challenge, against clinical signs and significantly reduced tracheal viral shedding. These results indicate that the NDV-vectored IBV vaccines are promising bivalent vaccine candidates to control both infectious bronchitis and Newcastle disease in Egypt.
Blog: ORCID API 3.0 is here!
Creators: name: Demeranville, Tom
Publisher: name: ORCID
Year: 2019
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences

description: We are pleased to announce the release of our version 3.0 API. Highlights include support for new affiliation types, research resources, token delegation, and improved source transparency.
title: Der Weg zur Social Software Lösung für Unternehmen: Bedürfnisanalyse für kollaborative Technologien
Creators: name: Diehl, Roland
name: Schubert, Petra
Publisher: name: Institut für Wirtschaftsinformatik
Year: 2012
Subjects: subject: 33
subject: 000

description: Nachdem Enterprise 2.0 Projekte aus der Experimentierphase entwachsen sind und mehrere erfolgreiche Implementierungen vorgewiesen werden können, ist es interessant, die Faktoren zu untersuchen, die eine Einführung erfolgreich oder weniger erfolgreich verlaufen lässt. Diese Arbeit präsentiert die Ergebnisse einer Untersuchung des Unternehmenskontexts, in dem Enterprise 2.0 Initiativen eingebettet sind. Die Analyse von 16 Praxisprojekten zeigt, dass es eine Vielzahl an Faktoren gibt, denen Unternehmen ihre Aufmerksamkeit bei der Einführung kollaborativer Technologien widmen (müssen). Exemplarische Ergebnisse aus dem Bereich Change Management zeigen eine hohe Abhängigkeit von der im Unternehmen angetroffenen Ausgangssituation und dem Bedarf einer entsprechenden Strategie für die Unterstützung solcher Einführungsprojekte.
description: Multikonferenz Wirtschaftsinformatik 2012 : Tagungsband der MKWI 2012
Modeling Market Mechanism with Evolutionary Games
Creators: name: Zhang, Yi-Cheng
Publisher: name: arXiv
Year: 1998
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: This is an essay solicited by Europhysics News, published in its March/April 1998 issue with slight modifications. We outline some highlights of the econophysics models, especially the so-called Minority model of competition and evolution. Even without the usual math, this essay offers an analytical solution to the Minority model, revealing some key features of the solution.
description: 4 pages, no figures
Dorstenia barnimiana Schweinf.
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Moraceae
Dorstenia
Dorstenia barnimiana

description: Dorstenia barnimiana Schweinf.  —
Habit: Herb.
Habitat: LMDF; up to 2 300 m. Distribution: I.
Voucher: N/A.
Reference: Fries & Fries (1924).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 50, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
title: Community-basierte Open Innovation von der Suche bis zur Implementierung – der Fall des Innovationsintermediärs innosabi
Creators: name: Hallerstede, Stefan
name: Bullinger, Angelika
name: Möslein, Kathrin
Publisher: name: Institut für Wirtschaftsinformatik
Year: 2012
Subjects: subject: 33
subject: 000

description: Durch Community-basierte Open Innovation können unternehmensexterne Akteure in den Innovationsprozess von Unternehmen einbezogen werden. Hierfür gibt es spezialisierte Intermediäre, welche die Relation, Interaktion und Kooperation zwischen Unternehmen und externen Innovatoren unterstützen. Die Ansätze der Intermediäre sind dabei meistens auf die Unterstützung der frühen Innovationsprozessschritte mittels einer Innovationscommunity spezialisiert: die Suche nach innovativen Konzepten sowie deren Selektion. Wenig Beachtung findet bisher ein integrierter Ansatz von der kooperativen Suche bis zur Implementierung. Dieser Artikel stellt eine Fallstudie des Innovationsintermediärs innosabi vor, der einen Entwicklungsprozess auf seiner Plattform unserAller gestaltet, welcher den Innovationsprozess von der Suche bis zur Implementierung durch eine Community unterstützt.
description: Multikonferenz Wirtschaftsinformatik 2012 : Tagungsband der MKWI 2012
Berezin-Toeplitz quantization and Berezin transform
Creators: name: Schlichenmaier, Martin
Publisher: name: arXiv
Year: 2000
Subjects: subject: Quantum Algebra (math.QA)
subject: Mathematical Physics (math-ph)
subject: Complex Variables (math.CV)
subject: Differential Geometry (math.DG)
subject: Symplectic Geometry (math.SG)
subject: Quantum Physics (quant-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 58F06; 53D55; 58G15; 53C55; 32C17; 81S10

description: In this lecture results on the Berezin-Toeplitz quantization of arbitrary compact quantizable Kaehler manifolds are presented. These results are obtained in joint work with M. Bordemann and E. Meinrenken. The existence of the Berezin-Toeplitz deformation quantization is also covered. Recent results obtained in joint work with A. Karabegov on the asymptotic expansion of the Berezin transform for arbitrary quantizable compact Kaehler manifolds are explained. As an application the asymptotic expansion of the Fubini-Study fundamental form under the coherent state embedding is considered. Some comments on the dynamics of the quantum operators are given. (This is an extended write-up of an invited lecture presented at the workshop ``Asymptotic properties of time evolutions in classical and quantum systems'', September 13-17, 1999, Bologna, Italy.)
description: 17 pages
Additional file 1 of Longitudinal assessment of IFN-I activity and immune profile in critically ill COVID-19 patients with acute respiratory distress syndrome
Creators: name: Venet, Fabienne
name: Cour, Martin
name: Rimmelé, Thomas
name: Viel, Sebastien
name: Yonis, Hodane
name: Coudereau, Remy
name: Amaz, Camille
name: Abraham, Paul
name: Monard, Céline
name: Casalegno, Jean-Sebastien
name: Brengel-Pesce, Karen
name: Lukaszewicz, Anne-Claire
name: Argaud, Laurent
name: Monneret, Guillaume
Publisher: name: figshare
Year: 2021
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1. Table S1. Immune response in critically ill COVID-19 patients, Table S2. Immune response in critically ill COVID-19 patients with or without ARDS, Table S3. Immune response in critically COVID-19 patients with ARDS according to status at D28, Table S4. Numbers of available values for each immune parameter at each time point; Figure S1. Flowchart and Survival Curves and Figure S2. Impact of viral load at admission.
Final-Downloaded-article-March-29-2019.pdf
Creators: name: Jram95@Hotmail.Com Jram95@Hotmail.Com
Publisher: name: figshare
Year: 2019
Subjects: subject: 30401 Biologically Active Molecules
subject: FOS: Chemical sciences

description: This article explains status of cytotoxic marine based metabolites in drug-space.
Unzipping Dynamics of Long DNAs
Creators: name: Cocco, S.
name: Monasson, R.
name: Marko, J. F.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Quantitative Biology (q-bio)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: The two strands of the DNA double helix can be `unzipped' by application of 15 pN force. We analyze the dynamics of unzipping and rezipping, for the case where the molecule ends are separated and re-approached at constant velocity. For unzipping of 50 kilobase DNAs at less than about 1000 bases per second, thermal equilibrium-based theory applies. However, for higher unzipping velocities, rotational viscous drag creates a buildup of elastic torque to levels above kBT in the dsDNA region, causing the unzipping force to be well above or well below the equilibrium unzipping force during respectively unzipping and rezipping, in accord with recent experimental results of Thomen et al. [Phys. Rev. Lett. 88, 248102 (2002)]. Our analysis includes the effect of sequence on unzipping and rezipping, and the transient delay in buildup of the unzipping force due to the approach to the steady state.
description: 15 pages Revtex file including 9 figures
Ficus exasperata Vahl
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Moraceae
Ficus
Ficus exasperata

description: Ficus exasperata Vahl  —
Habit: Tree, small tree or shrub.
Habitat: LMWF; up to 1 300 m. Distribution: I.
Voucher: N/A.
Reference: Fries & Fries (1924).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 51, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
title: [Le diable médecin]
title: la grande dame : la Duchesse douairière de Sénancourt
titleType: Subtitle
title: [Le diable médecin]
titleType: AlternativeTitle
Creators: name: Sue, Eugène
Publisher: name: Bibliothèque numérique romande
Year: 2021

description: Le Diable-Médecin vol. 2