cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Is the High-Resolution Coronal Imager Resolving Coronal Strands? Results from AR 12712
Creators: name: Williams, Thomas
name: Walsh, Robert W.
name: Winebarger, Amy R.
name: Brooks, David H.
name: Cirtain, Jonathan W.
name: Depontieu, Bart
name: Golub, Leon
name: Kobayashi, Ken
name: Mckenzie, David E.
name: Morton, Richard J.
name: Peter, Hardi
name: Rachmeler, Laurel A.
name: Savage, Sabrina L.
name: Testa, Paola
name: Tiwari, Sanjiv K.
name: Warren, Harry P.
name: Watkinson, Benjamin J.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Following the success of the first mission, the High-Resolution Coronal Imager (Hi-C) was launched for a third time (Hi-C 2.1) on 29th May 2018 from the White Sands Missile Range, NM, USA. On this occasion, 329 seconds of 17.2 nm data of target active region AR 12712 was captured with a cadence of ~4s, and a plate scale of 0.129''/pixel. Using data captured by Hi-C 2.1 and co-aligned observations from SDO/AIA 17.1 nm we investigate the widths of 49 coronal strands. We search for evidence of substructure within the strands that is not detected by AIA, and further consider whether these strands are fully resolved by Hi-C 2.1. With the aid of Multi-Scale Gaussian Normalization (MGN), strands from a region of low-emission that can only be visualized against the contrast of the darker, underlying moss are studied. A comparison is made between these low-emission strands with those from regions of higher emission within the target active region. It is found that Hi-C 2.1 can resolve individual strands as small as ~202km, though more typical strands widths seen are ~513km. For coronal strands within the region of low-emission, the most likely width is significantly narrower than the high-emission strands at ~388km. This places the low-emission coronal strands beneath the resolving capabilities of SDO/AIA, highlighting the need of a permanent solar observatory with the resolving power of Hi-C.
description: 19 pages, 10 images, 3 tables
Additional file 3 of Approaches to multidrug-resistant organism prevention and control in long-term care facilities for older people: a systematic review and meta-analysis
Creators: name: Wong, Valerie Wing Yu
name: Huang, Ying
name: Wei, Wan In
name: Wong, Samuel Yeung Shan
name: Kwok, Kin On
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Biotechnology
Cancer
Science Policy

description: Additional file 3. Interventions included in each studies.
Bare-Excitation Ground State of a Spinless-Fermion -- Boson Model and $W$-State Engineering in an Array of Superconducting Qubits and Resonators
Creators: name: Stojanovic, Vladimir M.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: This work unravels an interesting property of a one-dimensional lattice model that describes a single itinerant spinless fermion (excitation) coupled to zero-dimensional (dispersionless) bosons through two different nonlocal-coupling mechanisms. Namely, below a critical value of the effective excitation-boson coupling strength the exact ground state of this model is the zero-quasimomentum Bloch state of a bare (i.e., completely undressed) excitation. It is demonstrated here how this last property of the lattice model under consideration can be exploited for a fast, deterministic preparation of multipartite $W$ states in a readily realizable system of inductively-coupled superconducting qubits and microwave resonators.
description: final, published version; for a closely related realization of W states using Rydberg-dressed qubits, see arXiv:2101.11232 [ Phys. Rev. A 103, 022410 (2021) ]; for a non-technical summary of both works, see http://www.iap.tu-darmstadt.de/tqp/grp_stojanovic/Wentangle_PopularSummary.pdf
Review of studies about quantum communication and foundations of quantum mechanics at IENGF
Creators: name: Genovese, Marco
Publisher: name: arXiv
Year: 2003
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this proceeding I review the main experimental results obtained at IENGF (Turin, Italy) by using a source of entangled photons realised superposing, by means of an optical condenser, type I PDC produced in two crystals. More in details, after having described how this source is built, I will report on a Bell inequalities test obtained with it. Then I describe a recent innovative double slit experiment realised with a similar scheme. Finally, I hint about future developments of this activity at IENGF and in particular about a quantum cryptographic scheme in d=4.
description: to appear as invited talk in: SPIE Proceedings on Quantum Communications and Quantum Imaging (2003)
Dicyrtomina minuta sensu Stach 1957
Creators: name: Thibaud, Jean-Marc
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Symphypleona
Dicyrtomidae
Dicyrtomina
Dicyrtomina minuta

description: Dicyrtomina minuta (O. Fabricius, 1783) sensu Stach 1957 *
Podura minuta O. Fabricius, 1783: 307.
Dicyrtomina dorsimaculata Lubbock, 1873: 117.
Dicyrtomina minuta – Willem 1900: 63. — Stach 1957: 43.
DISTRIBUTION. — France. Bourlet 1841 (D. dorsimaculata).
Ariège. GrottedeL’Herm (Cauchois & Théodoridés 1954). — Massif del’Arize, 400- 1400 m (Deharveng & Lek 1995).
Auxois, Morvan, Côte-d’Or. Saint-Jean-de-Losne (Denis 1921, var. couloni).
Bas-Rhin. Merkwiller-Pechelbronn (Gillet & Ponge 2005).
Bouches-du-Rhône. Camargue (Poinsot 1973, 1979).
Essonne. Parcdu Laboratoiredu MNHN à Brunoy etforêt de Sénart (Ponge 1973). — Forêtde Sénart (Ponge 1980, 1993; Salmon & Ponge 1999; Ponge etal. 2002). — Maresde Sénart (Pichard etal. 1989). — Parcdu Laboratoiredu MNHNà Brunoy (Vannier & Kilbertus 1981; Betsch 1991; Chauvat & Ponge 2002).
Eure. Lyons-la-Forêt (Carl 1899).
Finistère. Prat-ar-Coum prèsde Lannilis (Delamare Deboutteville 1950c).
Haute-Garonne. Toulouse (Cassagnau & Delamare Deboutteville 1951; Cassagnau 1962a). — Ruisseaux de La Maure et de Ruau (Lek-Ang & Deharveng 2002). — Gar-Cagire près de Saint-Gaudens (Salmon etal. 2010).
Hautes-Pyrénées. Valléesde Couplanet dela Gargante (Cassagnau 1964a). — Hautevalléedel’Aureetmassif du Néouvielle (Lauga- Reyrel & Lauga 1995). — Montagned’Arize (Deharveng 1996).
Hauts-de-Seine. Maresde Clamart (Pichard etal. 1989).
Landes. Roquefort (Jeannenot 1957).
Loir-et-Cher. Forêt près de Salbris (Prat & Massoud 1980).
Loiret. Forêtd’Orléans (Ponge etal. 1993).
Nièvre. Parcrégionaldu Morvan (Ponge etal. 2003).
Norddela France. Finot 1890 (Dicyrtoma dorsi-maculata).
Pyrénées-Orientales. Forêtdela Massaneprèsde Banyuls-sur-Mer (Travé etal. 1954).
Seine-et-Marne. Forêtde Foljuif (Massoud etal. 1984). Sud-Ouestdela France; Pyrénées. Cassagnau 1961.
Tarn. Sidobre (Izarra 1969; Bonnet etal. 1972).
Vendée. Île-d’Yeu (Denis 1922a).
Vosges. Lorraine (Picard 1962).
PHYSIOLOGIE. — Vannier & Kilbertus 1981 (migration substances organo-minérales).
ÉCOLOGIE. — Picard 1962 (faune psammique); Bonnet et al. 1972 (écologie, muscicoles); Poinsot 1973, 1979; Ponge 1973, 1980, 1993; Prat & Massoud 1980 (sol forestier); Massoud etal. 1984 (piétinement); Pichard etal. 1989; Betsch 1991 (privation delitière); Ponge etal. 1993 (écologie expérimentale, litière), 2002 (toxicité, herbicide), 2003 (bioindicateur); Deharveng & Lek 1995; Deharveng 1996 (déboisement, reboisement); Salmon & Ponge 1999; Chauvat & Ponge 2002 (métaux lourds); Lek-Ang & Deharveng 2002 (zone humide); Gillet & Ponge 2005 (pollution); Salmon etal. 2010 (diversité, peuplement, endémisme).
description: Published as part of Thibaud, Jean-Marc, 2017, Catalogue des collemboles de France, pp. 297-436 in Zoosystema 39 (3) on pages 402-403, DOI: 10.5252/z2017n3a1, http://zenodo.org/record/5496272
Emerging Topical and Systemic JAK Inhibitors in Dermatology
Creators: name: Solimani, Farzan
name: Meier, Katharina
name: Ghoreschi, Kamran
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: JAK (Janus kinase)
subject: JAK inhibition
subject: JAK/STAT pathway
subject: autoimmune skin diseases
subject: immunopathogenesis
subject: inflammatory skin diseases
subject: pathophysiology
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Accumulating data on cellular and molecular pathways help to develop novel therapeutic strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic dermatitis, two clinically and immunologically well-defined disorders. Here, the elucidation of key pathogenic factors such as IL-17A/IL-23 on the one hand and IL-4/IL-13 on the other hand profoundly changed our therapeutic practice. The knowledge on intracellular pathways and governing factors is shifting our attention to new druggable molecules. Multiple cytokine receptors signal through Janus kinases (JAKs) and associated signal transducer and activators of transcription (STATs). Inhibition of JAKs can simultaneously block the function of multiple cytokines. Therefore, JAK inhibitors (JAKi) are emerging as a new class of drugs, which in dermatology can either be used systemically as oral drugs or locally in topical formulations. Inhibition of JAKs has been shown to be effective in various skin disorders. The first oral JAKi have been recently approved for the treatment of rheumatoid arthritis and psoriatic arthritis. Currently, multiple inhibitors of the JAK/STAT pathway are being investigated for skin diseases like alopecia areata, atopic dermatitis, dermatomyositis, graft-versus-host-disease, hidradenitis suppurativa, lichen planus, lupus erythematosus, psoriasis, and vitiligo. Here, we aim to discuss the immunological basis and current stage of development of JAKi in dermatology.
Megatoma Herbs 1791
Creators: name: Háva, Jiří
name: Herrmann, Andreas
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Dermestidae
Megatoma

description: 21. Megatoma Herbs, 1791
The Holarctic genus currently comprises 27 species in 2 subgenera (Háva 2015a, 2020).
  Megatoma (s. str.)
 Megatomaampla (Casey, 1900)...................... CAORWA
 Megatomabelfragei (LeConte, 1874).................. TX
 Megatomacylindrica (Kirby, 1837)................... ALAKAZCOIDMTNMORUTWAWY Megatoma dolia Beal, 1967.......................... CA
 Megatoma giffardi (Blaisdell, 1927)................... AL AK CA ID MT OR WA
 Megatomaleucochlidon Beal, 1967.................... CAORWA
 Megatoma polia Beal, 1967.......................... CA
 Megatomapubescens (Zetterstedt, 1828)............... ALCA ID; HOL
 Megatomavariegata (Horn, 1875).................... CACOID ME* NVORUTVTWA
  Megatoma (Pseudohadrotoma Kalík, 1951)
 Megatomafalsa (Horn, 1875)........................ CAIDOR
 Megatomagraeseri (Reitter, 1887).................... NYWI; HOL
 Megatomakaliki (Beal, 1967)........................ COIDMT
 Megatoma perversa (Fall, 1926)...................... AK CA CO MT
 Megatoma trichorhopalum (Beal, 1967)............... CA
 Megatomatrogodermoides (Beal, 1967)................ CANVOR
 Unrecognized species
 Megatoma angularis (Mannerheim, 1853)............. AK
description: Published as part of Háva, Jiří & Herrmann, Andreas, 2021, Checklist of Dermestidae (Insecta: Coleoptera: Bostrichoidea) of the United States, pp. 1-16 in Insecta Mundi 2021 (871) on page 13, DOI: 10.5281/zenodo.10089073
Nanoparticulate Metal Oxide Top Electrode Interface Modification Improves the Thermal Stability of Inverted Perovskite Photovoltaics
Creators: name: Papadas, Ioannis T.
name: Galatopoulos, Fedros
name: Armatas, Gerasimos S.
name: Tessler, Nir
name: Choulis, Stelios A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Solution processed γ-Fe2O3 nanoparticles via the solvothermal colloidal synthesis in conjunction with ligand-exchange method are used for interface modification of the top electrode in inverted perovskite solar cells. In comparison to more conventional top electrodes such as PC(70)BM/Al and PC(70)BM/AZO/Al, we show that incorporation of a γ-Fe2O3 provides an alternative solution processed top electrode (PC(70)BM/γ-Fe2O3/Al) that not only results in comparable power conversion efficiencies but also improved thermal stability of inverted perovskite photovoltaics. The origin of improved stability of inverted perovskite solar cells incorporating PC(70)BM/ γ-Fe2O3/Al under accelerated heat lifetime conditions is attributed to the acidic surface nature of γ-Fe2O3 and reduced charge trapped density within PC(70)BM/ γ-Fe2O3/Al top electrode interfaces.
description: 24 pages, 11 figures
Deep Hubble Space Telescope Imaging of IC 1613 II. The Star Formation History
Creators: name: Skillman, Evan D.
name: Tolstoy, Eline
name: Cole, Andrew A.
name: Dolphin, Andrew E.
name: Saha, Abhijit
name: Gallagher, J. S.
name: Dohm-Palmer, R. C.
name: Mateo, Mario
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present deep HST WFPC2 imaging of the Local Group dwarf irregular galaxy IC 1613. The photometry is the deepest to date for an isolated dwarf irregular galaxy. The resulting color-magnitude diagram (CMD) is analyzed using three different methods to derive a star formation history (SFH). All three find an enhanced star formation rate (SFR), from 3 to 6 Gyr ago, and similar age-metallicity relationships (AMR). A comparison of the newly observed outer field with an earlier studied central field of IC 1613 shows that the SFR in the outer field has been significantly depressed during the last Gyr. This implies that the optical scale length of the galaxy has been decreasing with time and that comparison of galaxies at intermediate redshift with present day galaxies should take this effect into account. We find strong similarities between IC 1613 and the more distant Milky Way dSph companions in that all are dominated by star formation at intermediate ages. In particular, the SFH and AMR for IC 1613 and Leo I are indistinguishable. This implies that dIrr galaxies cannot be distinguished from dSphs by their intermediate age stellar populations. This type of a SFH may also be evidence for slower or suppressed early star formation in dwarf galaxies due to photoionization after the reionization of the universe by background radiation. Assuming that IC 1613 is typical of a dIrr evolving in isolation, since most of the star formation occurs at intermediate ages, these dwarf systems cannot be responsible for the fast chemical enrichment of the IGM which is seen at high redshift. There is no evidence for any large amplitude bursts of star formation in IC 1613, and we find it highly unlikely that analogs of IC 1613 have contributed to the excess of faint blue galaxies in existing galaxy redshift surveys.
description: 32 pages, including 1 table and 17 figures, accepted for publication in the Astrophysical Journal October 10, 2003 issue
Research Data Management in 'GLAM': Managing Data for Cultural Heritage
Creators: name: Stewart, Sarah Anna
Publisher: name: Zenodo
Year: 2019
Subjects: cultural heritage, libraries, art galleries, museums, archives, digital collections, digital scholarship, data management, research data management, data, open research

description: A presentation given at the ‘Open Science Infrastructures for Big Cultural Data’ Masterclass, Dec. 13-15th, in Plovdiv, Bulgaria, looking at research data management in the context of open digital cultural collections, with a case study of the developments in data management and data management infrastructures at the British Library.
Metal-nonmetal transition and excitonic ground state in InAs/InSb quantum dots
Creators: name: He, Lixin
name: Bester, Gabriel
name: Zunger, Alex
Publisher: name: arXiv
Year: 2004
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Using atomistic pseudopotential and configuration-interaction many-body calculations, we predict a metal-nonmetal transition and an excitonic ground state in the InAs/InSb quantum dot (QD) system. For large dots, the conduction band minimum of the InAs dot lies below the valence band maximum of the InSb matrix. Due to quantum confinement, at a critical size calculated here for various shapes, the single-particle gap $E_g$ becomes very small. Strong electron-hole correlation effects are induced by the spatial proximity of the electron and hole wavefunctions, and by the lack of strong (exciton unbinding) screening, afforded by the existence of fully discrete 0D confined energy levels. These correlation effects overcome $E_g$, leading to the formation of a bi-excitonic ground state (two electrons in InAs and two holes in InSb) being energetically more favorable (by $\sim$ 15 meV) than the state without excitons. We discuss the excitonic phase transition on QD arrays in the low dot density limit.
Controlling the Growth of Constraints in Hyperbolic Evolution Systems
Creators: name: Lindblom, Lee
name: Scheel, Mark A.
name: Kidder, Lawrence E.
name: Pfeiffer, Harald P.
name: Shoemaker, Deirdre
name: Teukolsky, Saul A.
Publisher: name: arXiv
Year: 2004
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Motivated by the need to control the exponential growth of constraint violations in numerical solutions of the Einstein evolution equations, two methods are studied here for controlling this growth in general hyperbolic evolution systems. The first method adjusts the evolution equations dynamically, by adding multiples of the constraints, in a way designed to minimize this growth. The second method imposes special constraint preserving boundary conditions on the incoming components of the dynamical fields. The efficacy of these methods is tested by using them to control the growth of constraints in fully dynamical 3D numerical solutions of a particular representation of the Maxwell equations that is subject to constraint violations. The constraint preserving boundary conditions are found to be much more effective than active constraint control in the case of this Maxwell system.
description: final version to be published in Physical Review D
Dicyrtomina ornata sensu Stach 1957
Creators: name: Thibaud, Jean-Marc
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Symphypleona
Dicyrtomidae
Dicyrtomina
Dicyrtomina ornata

description: Dicyrtomina ornata (Nicolet, 1842) sensu Stach 1957 *
Smynthurus ornatus Nicolet, 1842: 83.
Dicyrtomina ornata – Stach 1957: 51.
DISTRIBUTION. — France. Bourlet 1845 (Sminthurus coulonii).
Ariège. Cassagne etal. 2004.
Aveyron. Espalion (Nayrolles 1988).
Haute-Garonne. Toulouse (Cassagnau 1962a).
Hautes-Pyrénées. Vallées de Couplan et de la Gargante (Cassagnau 1964a). — Hautevalléedel’Aureetmassif du Néouvielle (Lauga-Reyrel & Lauga 1995). — Pyrénéescentrales (Cassagne etal. 2003, 2004).
Loir-et-Cher. Forêt près de Salbris (Prat & Massoud 1980).
Nièvre. Parcrégionaldu Morvan (Ponge etal. 2003).
Nord. Bois des Asturies près d’Auby (Gillet & Ponge 2003).
Pyrénées-Orientales. Station de ski de Calmazeille-Formiguères (Gers & Izarra 1983).
Tarn, Aude. Montagne Noire (Cassagnau 1965).
Tarn. Sidobre (Izarra 1969; Bonnet etal. 1970, 1972, 1975).
Val-de-Marne. Saint-Maurice (Lécaillon 1901, Papirius minutus var. couloni).
Var. Massif des Maures (Poinsot-Balaguer & Kabakibi 1987).
CHÉTOTAXIE, MORPHO- ANATOMIE. — Nayrolles 1988 (chétotaxie, pattes).
ÉCOLOGIE. — Cassagnau 1965 (écologie, sol); Bonnet etal. 1970, 1972, 1975 (écologie, muscicoles); Prat & Massoud 1980 (sol forestier); Gers & Izarra 1983 (biocénose); Poinsot-Balaguer & Kabakibi 1987; Cassagne etal. 2003, 2004; Gillet & Ponge 2003 (pollution, métaux); Ponge etal. 2003 (bioindicateur).
description: Published as part of Thibaud, Jean-Marc, 2017, Catalogue des collemboles de France, pp. 297-436 in Zoosystema 39 (3) on page 403, DOI: 10.5252/z2017n3a1, http://zenodo.org/record/5496272
Fluctuation-driven superconductivity in Sr$_2$RuO$_4$ from weak repulsive interactions
Creators: name: Rømer, Astrid T.
name: Andersen, Brian M.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We provide results for the leading superconducting instabilities for a model pertaining to Sr$_2$RuO$_4$ obtained within spin-fluctuation mediated superconductivity in the very weak-coupling limit. The theory incorporates spin-orbit coupling (SOC) effects both in the band structure and in the pairing kernel in the form of associated magnetic anisotropies. The leading superconducting phase is found to be $d_{x^2-y^2}$ and a nodal $s$-wave state. However, the odd-parity helical solution can become leading either for small SOC and Hund's coupling $J$ in the weak $U$-limit, or in the opposite limit with large SOC and $J$ at larger values of the Hubbard-$U$. The odd-parity chiral solution is never found to be leading. Finally we discuss the form of the resulting superconducting spectral gaps in the different explored parameter regimes.
description: 5 pages, 5 figures
PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells
Creators: name: Zhang, Kevin Sun
name: Schecker, Johannes
name: Krull, Alexandros
name: Riechert, Eva
name: Jürgensen, Lonny
name: Kamuf-Schenk, Verena
name: Burghaus, Jana
name: Kiper, Leon
name: Cao Ho, Thanh
name: Wöltje, Kerstin
name: Stangl, Verena
name: Katus, Hugo A.
name: Stangl, Karl
name: Völkers, Mirko
name: Althoff, Till F.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: Atherosclerosis
subject: Endothelial-Specific PRAS40
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Endothelial pro-inflammatory activation plays a pivotal role in atherosclerosis, and many pro-inflammatory and atherogenic signals converge upon mechanistic target of rapamycin (mTOR). Inhibitors of mTOR complex 1 (mTORC1) reduced atherosclerosis in preclinical studies, but side effects including insulin resistance and dyslipidemia limit their clinical use in this context. Therefore, we investigated PRAS40, a cell type-specific endogenous modulator of mTORC1, as alternative target. Indeed, we previously found PRAS40 gene therapy to improve metabolic profile; however, its function in endothelial cells and its role in atherosclerosis remain unknown. Here we show that PRAS40 negatively regulates endothelial mTORC1 and pro-inflammatory signaling. Knockdown of PRAS40 in endothelial cells promoted TNFα-induced mTORC1 signaling, proliferation, upregulation of inflammatory markers and monocyte recruitment. In contrast, PRAS40-overexpression blocked mTORC1 and all measures of pro-inflammatory signaling. These effects were mimicked by pharmacological mTORC1-inhibition with torin1. In an in vivo model of atherogenic remodeling, mice with induced endothelium-specific PRAS40 deficiency showed enhanced endothelial pro-inflammatory activation as well as increased neointimal hyperplasia and atherosclerotic lesion formation. These data indicate that PRAS40 suppresses atherosclerosis via inhibition of endothelial mTORC1-mediated pro-inflammatory signaling. In conjunction with its favourable effects on metabolic homeostasis, this renders PRAS40 a potential target for the treatment of atherosclerosis.
Increased compensatory kidney workload results in cellular damage in a short time porcine model of mixed acidemia – Is acidemia a ‘first hit’ in acute kidney injury?
Creators: name: Russ, Martin
name: Ott, Sascha
name: Bedarf, Janis R.
name: Kirschfink, Michael
name: Hiebl, Bernhard
name: Unger, Juliane K.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: acute kidney injury
subject: AKI
subject: hypoxemia
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Acute kidney injury (AKI) corrupts the outcome of about 50% of all critically ill patients. We investigated the possible contribution of the pathology acidemia on the development of AKI. Pigs were exposed to acidemia, acidemia plus hypoxemia or a normal acid-base balance in an experimental setup, which included mechanical ventilation and renal replacement therapy to facilitate biotrauma caused by extracorporeal therapies. Interestingly, extensive histomorphological changes like a tubular loss of cell barriers occurred in the kidneys after just 5 hours exposure to acidemia. The additional exposure to hypoxemia aggravated these findings. These 'early' microscopic pathologies opposed intra vitam data of kidney function. They did not mirror cellular or systemic patterns of proinflammatory molecules (like TNF-α or IL 18) nor were they detectable by new, sensitive markers of AKI like Neutrophil gelatinase-associated lipocalin. Instead, the data suggest that the increased renal proton excretion during acidemia could be an 'early' first hit in the multifactorial pathogenesis of AKI.
Proximity-Based Emergency Response Communities for Patients With Allergies Who Are at Risk of Anaphylaxis: Clustering Analysis and Scenario-Based Survey Study
Creators: name: Yablowitz, Michal Gaziel
name: Dölle, Sabine
name: Schwartz, David G.
name: Worm, Margitta
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: anaphylaxis
subject: consumer health informatics
subject: emergency responders
subject: social networking
subject: telemedicine
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: BACKGROUND: Anaphylaxis is a potentially fatal allergic reaction. However, many patients at risk of anaphylaxis who should permanently carry a life-saving epinephrine auto injector (EAI) do not carry one at the moment of allergen exposure. The proximity-based emergency response communities (ERC) strategy suggests speeding EAI delivery by alerting patient-peers carrying EAI to respond and give their EAI to a nearby patient in need. OBJECTIVES: This study had two objectives: (1) to analyze 10,000 anaphylactic events from the European Anaphylaxis Registry (EAR) by elicitor and location in order to determine typical anaphylactic scenarios and (2) to identify patients' behavioral and spatial factors influencing their response to ERC emergency requests through a scenario-based survey. METHODS: Data were collected and analyzed in two phases: (1) clustering 10,000 EAR records by elicitor and incident location and (2) conducting a two-center scenario-based survey of adults and parents of minors with severe allergy who were prescribed EAI, in Israel and Germany. Each group received a four-part survey that examined the effect of two behavioral constructs-shared identity and diffusion of responsibility-and two spatial factors-emergency time and emergency location-in addition to sociodemographic data. We performed descriptive, linear correlation, analysis of variance, and t tests to identify patients' decision factors in responding to ERC alerts. RESULTS: A total of 53.1% of EAR cases were triggered by food at patients' home, and 46.9% of them were triggered by venom at parks. Further, 126 Israeli and 121 German participants completed the survey and met the inclusion criteria. Of the Israeli participants, 80% were parents of minor patients with a risk of anaphylaxis due to food allergy; their mean age was 32 years, and 67% were women. In addition, 20% were adult patients with a mean age of 21 years, and 48% were female. Among the German patients, 121 were adults, with an average age of 47 years, and 63% were women. In addition, 21% were allergic to food, 75% were allergic to venom, and 2% had drug allergies. The overall willingness to respond to ERC events was high. Shared identity and the willingness to respond were positively correlated (r=0.51, P
Dicyrtomina saundersi sensu Stach 1957
Creators: name: Thibaud, Jean-Marc
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Symphypleona
Dicyrtomidae
Dicyrtomina
Dicyrtomina saundersi

description: Dicyrtomina saundersi (Lubbock, 1862) sensu Stach 1957
Papirius saundersi Lubbock, 1862b: 438.
Dicyrtomina saundersi – Stach 1957: 50.
DISTRIBUTION. — Ardèche. Lieu-dit Les Mazes près de Vallon- Pont-d’Arc (Stomp etal. 1982).
Bouches-du-Rhône. Forêtde Cadarache (Rougon & Rougon 1970). — Camargue (Poinsot 1973). — Cadarache (Poinsot-Balaguer 1976d).
Corse. Poinsot 1970?, 1978.
ÉCOLOGIE. — Rougon & Rougon 1970; Poinsot 1973; Poinsot- Balaguer 1976d (irradiation).
description: Published as part of Thibaud, Jean-Marc, 2017, Catalogue des collemboles de France, pp. 297-436 in Zoosystema 39 (3) on page 403, DOI: 10.5252/z2017n3a1, http://zenodo.org/record/5496272
Ketogenic diet and fasting diet as Nutritional Approaches in Multiple Sclerosis (NAMS): protocol of a randomized controlled study
Creators: name: Bahr, Lina Samira
name: Bock, Markus
name: Liebscher, Daniela
name: Bellmann-Strobl, Judith
name: Franz, Liane
name: Prüß, Alexandra
name: Schumann, Dania
name: Piper, Sophie K.
name: Kessler, Christian S.
name: Steckhan, Nico
name: Michalsen, Andreas
name: Paul, Friedemann
name: Mähler, Anja
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Multiple sclerosis
subject: Dietary intervention
subject: Ketogenic diet
subject: Intermittent fasting
subject: Anti-inflammatory diet
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: BACKGROUND: Multiple sclerosis (MS) is the most common inflammatory disease of the central nervous system in young adults that may lead to progressive disability. Since pharmacological treatments may have substantial side effects, there is a need for complementary treatment options such as specific dietary approaches. Ketone bodies that are produced during fasting diets (FDs) and ketogenic diets (KDs) are an alternative and presumably more efficient energy source for the brain. Studies on mice with experimental autoimmune encephalomyelitis showed beneficial effects of KDs and FDs on disease progression, disability, cognition and inflammatory markers. However, clinical evidence on these diets is scarce. In the clinical study protocol presented here, we investigate whether a KD and a FD are superior to a standard diet (SD) in terms of therapeutic effects and disease progression. METHODS: This study is a single-center, randomized, controlled, parallel-group study. One hundred and eleven patients with relapsing-remitting MS with current disease activity and stable immunomodulatory therapy or no disease-modifying therapy will be randomized to one of three 18-month dietary interventions: a KD with a restricted carbohydrate intake of 20-40 g/day; a FD with a 7-day fast every 6 months and 14-h daily intermittent fasting in between; and a fat-modified SD as recommended by the German Nutrition Society. The primary outcome measure is the number of new T2-weighted MRI lesions after 18 months. Secondary endpoints are safety, changes in relapse rate, disability progression, fatigue, depression, cognition, quality of life, changes of gut microbiome as well as markers of inflammation, oxidative stress and autophagy. Safety and feasibility will also be assessed. DISCUSSION: Preclinical data suggest that a KD and a FD may modulate immunity, reduce disease severity and promote remyelination in the mouse model of MS. However, clinical evidence is lacking. This study is the first clinical study investigating the effects of a KD and a FD on disease progression of MS.
Electronic supplementary material for this manuscript from Early Oligocene chinchilloid caviomorphs from Puerto Rico and the initial rodent colonization of the West Indies
Creators: name: Marivaux, Laurent
name: Vélez-Juarbe, Jorge
name: Merzeraud, Gilles
name: Pujos, François
name: Lázaro W. Viñola López
name: Boivin, Myriam
name: Santos-Mercado, Hernán
name: Cruz, Eduardo J.
name: Grajales, Alexandra
name: Padilla, James
name: Vélez-Rosado, Kevin I.
name: Mélody Philippon
name: Jean-Len Léticée
name: Münch, Philippe
name: Pierre-Olivier Antoine
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences
subject: 60301 Animal Systematics and Taxonomy
subject: 60310 Plant Systematics and Taxonomy

description: This ESM includes: the fossil descriptions, additional morphological illustrations, data associated to the phylogenetic analyses (assumptions, selected characters, and data Matrix).
Aortic volume determines global end-diastolic volume measured by transpulmonary thermodilution
Creators: name: Akohov, Aleksej
name: Barner, Christoph
name: Grimmer, Steffen
name: Francis, Roland CE
name: Wolf, Stefan
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Aorta
subject: Aortic volume
subject: Global end-diastolic volume
subject: GEDV
subject: GEDVI
subject: Transpulmonary thermodilution
subject: Vena cava
subject: Vena cava volume
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: BACKGROUND: Global end-diastolic volume (GEDV) measured by transpulmonary thermodilution is regarded as indicator of cardiac preload. A bolus of cold saline injected in a central vein travels through the heart and lung, but also the aorta until detection in a femoral artery. While it is well accepted that injection in the inferior vena cava results in higher values, the impact of the aortic volume on GEDV is unknown. In this study, we hypothesized that a larger aortic volume directly translates to a numerically higher GEDV measurement. METHODS: We retrospectively analyzed data from 88 critically ill patients with thermodilution monitoring and who did require a contrast-enhanced thoraco-abdominal computed tomography scan. Aortic volumes derived from imaging were compared with GEDV measurements in temporal proximity. RESULTS: Median aortic volume was 194 ml (interquartile range 147 to 249 ml). Per milliliter increase of the aortic volume, we found a GEDV increase by 3.0 ml (95% CI 2.0 to 4.1 ml, p < 0.001). In case a femoral central venous line was used for saline bolus injection, GEDV raised additionally by 2.1 ml (95% CI 0.5 to 3.7 ml, p = 0.01) per ml volume of the vena cava inferior. Aortic volume explained 59.3% of the variance of thermodilution-derived GEDV. When aortic volume was included in multivariate regression, GEDV variance was unaffected by sex, age, body height, and weight. CONCLUSIONS: Our results suggest that the aortic volume is a substantial confounding variable for GEDV measurements performed with transpulmonary thermodilution. As the aorta is anatomically located after the heart, GEDV should not be considered to reflect cardiac preload. Guiding volume management by raw or indexed reference ranges of GEDV may be misleading.
Dicyrtomina violacea sensu Ionesco 1916
Creators: name: Thibaud, Jean-Marc
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Symphypleona
Dicyrtomidae
Dicyrtomina
Dicyrtomina violacea

description: Dicyrtomina violacea (Krausbauer, 1898) sensu Ionesco 1916 *
Papirius violaceus Krausbauer, 1898: 499.
Dicyrtomina violacea – Ionesco 1916: 510.
DISTRIBUTION. — Haute-Saône. Salinede Gouhenans (Denis 1924c).
TAXONOMIE. — Denis 1924c (redescription).
description: Published as part of Thibaud, Jean-Marc, 2017, Catalogue des collemboles de France, pp. 297-436 in Zoosystema 39 (3) on page 403, DOI: 10.5252/z2017n3a1, http://zenodo.org/record/5496272
*-Autonomous Envelopes and Conservativity
Creators: name: Shulman, Michael
Publisher: name: arXiv
Year: 2020
Subjects: subject: Category Theory (math.CT)
subject: Logic in Computer Science (cs.LO)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: We prove 2-categorical conservativity for any {0,T}-free fragment of MALL over its corresponding intuitionistic version: that is, that the universal map from a closed symmetric monoidal category to the *-autonomous category that it freely generates is fully faithful, and similarly for other doctrines. This implies that linear logics and graphical calculi for *-autonomous categories can also be interpreted canonically in closed symmetric monoidal categories. In particular, every closed symmetric monoidal category can be fully embedded in a *-autonomous category, preserving both tensor products and internal-homs. In fact, we prove this directly first with a Yoneda-style embedding (an enhanced "Hyland envelope" that can be regarded as a polycategorical form of Day convolution), and deduce 2-conservativity afterwards from Hyland-Schalk double gluing and a technique of Lafont. The same is true for other fragments of *-autonomous structure, such as linear distributivity, and the embedding can be enhanced to preserve any desired family of nonempty limits and colimits.
description: In Proceedings Linearity&TLLA 2020, arXiv:2112.14305
Furniture Free Mapping using 3D Lidars
Creators: name: He, Zhenpeng
name: Hou, Jiawei
name: Schwertfeger, Sören
Publisher: name: arXiv
Year: 2019
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Mobile robots depend on maps for localization, planning, and other applications. In indoor scenarios, there is often lots of clutter present, such as chairs, tables, other furniture, or plants. While mapping this clutter is important for certain applications, for example navigation, maps that represent just the immobile parts of the environment, i.e. walls, are needed for other applications, like room segmentation or long-term localization. In literature, approaches can be found that use a complete point cloud to remove the furniture in the room and generate a furniture free map. In contrast, we propose a Simultaneous Localization And Mapping (SLAM)-based mobile laser scanning solution. The robot uses an orthogonal pair of Lidars. The horizontal scanner aims to estimate the robot position, whereas the vertical scanner generates the furniture free map. There are three steps in our method: point cloud rearrangement, wall plane detection and semantic labeling. In the experiment, we evaluate the efficiency of removing furniture in a typical indoor environment. We get $99.60\%$ precision in keeping the wall in the 3D result, which shows that our algorithm can remove most of the furniture in the environment. Furthermore, we introduce the application of 2D furniture free mapping for room segmentation.
Data Mining in Clinical Trial Text: Transformers for Classification and Question Answering Tasks
Creators: name: Schmidt, Lena
name: Weeds, Julie
name: Higgins, Julian P. T.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computation and Language (cs.CL)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: This research on data extraction methods applies recent advances in natural language processing to evidence synthesis based on medical texts. Texts of interest include abstracts of clinical trials in English and in multilingual contexts. The main focus is on information characterized via the Population, Intervention, Comparator, and Outcome (PICO) framework, but data extraction is not limited to these fields. Recent neural network architectures based on transformers show capacities for transfer learning and increased performance on downstream natural language processing tasks such as universal reading comprehension, brought forward by this architecture's use of contextualized word embeddings and self-attention mechanisms. This paper contributes to solving problems related to ambiguity in PICO sentence prediction tasks, as well as highlighting how annotations for training named entity recognition systems are used to train a high-performing, but nevertheless flexible architecture for question answering in systematic review automation. Additionally, it demonstrates how the problem of insufficient amounts of training annotations for PICO entity extraction is tackled by augmentation. All models in this paper were created with the aim to support systematic review (semi)automation. They achieve high F1 scores, and demonstrate the feasibility of applying transformer-based classification methods to support data mining in the biomedical literature.
Drusilla penicillata ASSING 2019
Creators: name: Assing, Volker
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Drusilla
Drusilla penicillata

description: Drusilla penicillata ASSING, 2019
 M a t e r i a l e x a m i n e d PHILIPPINES: 3♂♂, 2♀♀ [partly teneral], Mindanao, Araibo, Pantukan, Compostela Valley, Candalaga Mts., 7°16'35''N, 126°10'13''E, 900 m, 4.V.2019, leg. Shavrin (cAss).
 C o m m e n t: Drusilla penicillata was previously known only from two localities in Central Mindanao.
description: Published as part of Assing, Volker, 2019, Four new species and additional records of Lomechusini from Mindanao, Philippines (Coleoptera, Staphylinidae, Aleocharinae), pp. 789-802 in Linzer biologische Beiträge 51 (2) on page 790, DOI: 10.5281/zenodo.5113804
Additional file 9 of Conversion between 100-million-year-old duplicated genes contributes to rice subspecies divergence
Creators: name: Wei, Chendan
name: Wang, Zhenyi
name: Wang, Jianyu
name: Teng, Jia
name: Shen, Shaoqi
name: Xiao, Qimeng
name: Bao, Shoutong
name: Feng, Yishan
name: Zhang, Yan
name: Li, Yuxian
name: Sun, Sangrong
name: Yue, Yuanshuai
name: Wu, Chunyang
name: Wang, Yanli
name: Zhou, Tianning
name: Xu, Wenbo
name: Yu, Jigao
name: Wang, Li
name: Wang, Jinpeng
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 9: Table S7. Relationship between the block length and the gene conversion rate in the three rice subspecies genomes.
The Effects of Binary Evolution on the Dynamics of Core Collapse and Neutron-Star Kicks
Creators: name: Podsiadlowski, Ph.
name: Langer, N.
name: Poelarends, A. J. T.
name: Rappaport, S.
name: Heger, A.
name: Pfahl, E.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We systematically examine how the presence in a binary affects the final core structure of a massive star and its consequences for the subsequent supernova explosion. Interactions with a companion star may change the final rate of rotation, the size of the helium core, the strength of carbon burning and the final iron core mass. Stars with initial masses larger than \sim 11\Ms that experiece core collapse will generally have smaller iron cores at the time of the explosion if they lost their envelopes due to a previous binary interaction. Stars below \sim 11\Ms, on the other hand, can end up with larger helium and metal cores if they have a close companion, since the second dredge-up phase which reduces the helium core mass dramatically in single stars does not occur once the hydrogen envelope is lost. We find that the initially more massive stars in binary systems with masses in the range 8 - 11\Ms are likely to undergo an electron-capture supernova, while single stars in the same mass range would end as ONeMg white dwarfs. We suggest that the core collapse in an electron-capture supernova (and possibly in the case of relatively small iron cores) leads to a prompt explosion rather than a delayed neutrino-driven explosion and that this naturally produces neutron stars with low-velocity kicks. This leads to a dichotomous distribution of neutron star kicks, as inferred previously, where neutron stars in relatively close binaries attain low kick velocities. We illustrate the consequences of such a dichotomous kick scenario using binary population synthesis simulations and discuss its implications. This scenario has also important consequences for the minimum initial mass of a massive star that becomes a neutron star. (Abbreviated.)
description: 8 pages, 3 figures, submitted to ApJ, updated version
Improved Visualization of the Necrotic Zone after Microwave Ablation Using Computed Tomography Volume Perfusion in an In Vivo Porcine Model
Creators: name: Bressem, Keno K.
name: Vahldiek, Janis L.
name: Erxleben, Christoph
name: Shnayien, Seyd
name: Poch, Franz
name: Geyer, Beatrice
name: Lehmann, Kai S.
name: Hamm, B.
name: Niehues, Stefan M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: CT perfusion
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: After hepatic microwave ablation, the differentiation between fully necrotic and persistent vital tissue through contrast enhanced CT remains a clinical challenge. Therefore, there is a need to evaluate new imaging modalities, such as CT perfusion (CTP) to improve the visualization of coagulation necrosis. MWA and CTP were prospectively performed in five healthy pigs. After the procedure, the pigs were euthanized, and the livers explanted. Orthogonal histological slices of the ablations were stained with a vital stain, digitalized and the necrotic core was segmented. CTP maps were calculated using a dual-input deconvolution algorithm. The segmented necrotic zones were overlaid on the DICOM images to calculate the accuracy of depiction by CECT/CTP compared to the histological reference standard. A receiver operating characteristic analysis was performed to determine the agreement/true positive rate and disagreement/false discovery rate between CECT/CTP and histology. Standard CECT showed a true positive rate of 81% and a false discovery rate of 52% for display of the coagulation necrosis. Using CTP, delineation of the coagulation necrosis could be improved significantly through the display of hepatic blood volume and hepatic arterial blood flow (p
Initiation à la gestion des notes et à l'écriture académique avec Obsidian
Creators: name: Belvèze, Damien
Publisher: name: Zenodo
Year: 2022
Subjects: Obsidian, PhD training, notetaking app, Pandoc, Zotero

description: Formation doctorale de 3 heures (29 juin 2022, BU Rennes 1) Les consignes que les étudiants doivent suivre sont résumées dans le fichier consignes.pdf La formation comporte : - une présentation de la méthode de classement des notes Zettelkasten - une présentation générale du logiciel Obsidian - une initiation à la syntaxe markdown - une méthode pour réaliser des diaporamas avec Obsidian - une méthode pour utiliser Zotero en lien avec Obsidian - une initiation à la conversion avec Pandoc. Les fichiers déposés comportent également un script (bracketeraser) conçu pour faciliter la conversion de notes prises avec Obsidian aux étudiants qui ne souhaitent pas utiliser Pandoc en ligne de commandes.