cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Probabilistic existence results for separable codes
Creators: name: Blackburn, Simon R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: Discrete Mathematics (cs.DM)
subject: Combinatorics (math.CO)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Separable codes were defined by Cheng and Miao in 2011, motivated by applications to the identification of pirates in a multimedia setting. Combinatorially, $\overline{t}$-separable codes lie somewhere between $t$-frameproof and $(t-1)$-frameproof codes: all $t$-frameproof codes are $\overline{t}$-separable, and all $\overline{t}$-separable codes are $(t-1)$-frameproof. Results for frameproof codes show that (when $q$ is large) there are $q$-ary $\overline{t}$-separable codes of length $n$ with approximately $q^{\lceil n/t\rceil}$ codewords, and that no $q$-ary $\overline{t}$-separable codes of length $n$ can have more than approximately $q^{\lceil n/(t-1)\rceil}$ codewords. The paper provides improved probabilistic existence results for $\overline{t}$-separable codes when $t\geq 3$. More precisely, for all $t\geq 3$ and all $n\geq 3$, there exists a constant $κ$ (depending only on $t$ and $n$) such that there exists a $q$-ary $\overline{t}$-separable code of length $n$ with at least $κq^{n/(t-1)}$ codewords for all sufficiently large integers $q$. This shows, in particular, that the upper bound (derived from the bound on $(t-1)$-frameproof codes) on the number of codewords in a $\overline{t}$-separable code is realistic. The results above are more surprising after examining the situation when $t=2$. Results due to Gao and Ge show that a $q$-ary $\overline{2}$-separable code of length $n$ can contain at most $\frac{3}{2}q^{2\lceil n/3\rceil}-\frac{1}{2}q^{\lceil n/3\rceil}$ codewords, and that codes with at least $κq^{2n/3}$ codewords exist. So optimal $\overline{2}$-separable codes behave neither like $2$-frameproof nor $1$-frameproof codes. Also, the Gao--Ge bound is strengthened to show that a $q$-ary $\overline{2}$-separable code of length $n$ can have at most \[ q^{\lceil 2n/3\rceil}+\tfrac{1}{2}q^{\lfloor n/3\rfloor}(q^{\lfloor n/3\rfloor}-1) \] codewords.
description: 16 pages. Typos corrected and minor changes since last version. Accepted by IEEE Transactions on Information Theory
Suppl. File 2 from Within-population variability in a moth sex pheromone blend, part 2: selection towards fixation
Creators: name: Groot, Astrid T.
name: Wijk, Michiel Van
name: Villacis-Perez, Ernesto
name: Kuperus, Peter
name: Schöfl, Gerhard
name: Veldhuizen, Dennis Van
name: Heckel, David G.
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology

description: Gels showing the screens of the stop codon
(1430) Ellen [Cary]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
I-BiDaaS - D7.1: Project Website
Creators: name: Akarmazyan, Siranush
Publisher: name: Zenodo
Year: 2018

description: This deliverable presents the work performed in WP7/Task7.2 “Communication strategy triggering awareness and new business opportunities” with respect to design and development of the I-BiDaaS website to public use. Since the aim of WP7 is supervising the integrity and consistency of all dissemination efforts for creating awareness on the I-BiDaaS developments, the main objective of this deliverable is to develop the underlying infrastructure in order to effectively establish the I-BiDaaS online presence for reaching out to the widest possible audiences and provide a consistent source of information for all kind of dissemination efforts.
Anatomical and physiological development of the Xenopus embryonic motor system in the absence of neural activity
Creators: name: Haverkamp, L. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: Embryos of Xenopus laevis were continually immobilized by immersion in solutions of either chloretone or lidocaine, from the late neural-fold stage to the approximate time of hatching. Such treatment has been shown to result in only transient quantitative effects on swimming behavior. Chronic immobilization was without either immediate or long- term effect on the ventral root output exhibited during “fictive” swimming episodes. Development under these conditions of diminished or absent neural activity similarly had no effects on a number of measures of the size and complexity of motoneuron dendritic arborizations. These results support the premise that the early development of specific neuronal morphology and connectivity may be largely independent of functional activity.
Suppl. File 3 from Within-population variability in a moth sex pheromone blend, part 2: selection towards fixation.
Creators: name: Groot, Astrid T.
name: Wijk, Michiel Van
name: Villacis-Perez, Ernesto
name: Kuperus, Peter
name: Schöfl, Gerhard
name: Veldhuizen, Dennis Van
name: Heckel, David G.
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology

description: Aligned nucleotide sequences of the entire LPAQ delta-11-desaturase gene (gDNA) of 47 individuals. “L allel cDNA” refers to the consensus sequence of the cds allele in the High selection line, “L allel gDNA” to the consensus genomic DNA sequence in the High selection line (the names “High” and “Low” are reversed in our rearing. To stay consistent with our previous publication, our reference to “High” and “Low” in this manuscript is the same as in Groot et al. 2014). H56 refers to plate H56 of DGH, containing individuals from the JEN2 rearing of Jena. Individuals with numbers starting with 9, 10, 13, 14, 15, 18 refer to individuals from our selection lines, where the first number is the rearing generation (i.e. 9 refers to the 9th generation of rearing, which is the 5th generation of selection). Individuals with numbers starting with 35 or 46 are from backcross families 35 and 46, respectively.
The evolution of the X-ray phase lags during the outbursts of the black hole candidate GX 339-4
Creators: name: Altamirano, Diego
name: Mendez, Mariano
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Owing to the frequency and reproducibility of its outbursts, the black-hole candidate GX 339-4 has become the standard against which the outbursts of other black-hole candidate are matched up. Here we present the first systematic study of the evolution of the X-ray lags of the broad-band variability component (0.008-5 Hz) in GX 339-4 as a function of the position of the source in the hardness-intensity diagram. The hard photons always lag the soft ones, consistent with previous results. In the low-hard state the lags correlate with X-ray intensity, and as the source starts the transition to the intermediate/soft states, the lags first increase faster, and then appear to reach a maximum, although the exact evolution depends on the outburst and the energy band used to calculate the lags. The time of the maximum of the lags appears to coincide with a sudden drop of the Optical/NIR flux, the fractional RMS amplitude of the broadband component in the power spectrum, and the appearance of a thermal component in the X-ray spectra, strongly suggesting that the lags can be very useful to understand the physical changes that GX 339-4 undergoes during an outburst. We find strong evidence for a connection between the evolution of the cut-off energy of the hard component in the energy spectrum and the phase lags, suggesting that the average magnitude of the lags is correlated with the properties of the corona/jet rather than those of the disc. Finally, we show that the lags in GX 339-4 evolve in a similar manner to those of the black-hole candidate Cygnus X-1, suggesting similar phenomena could be observable in other black-hole systems.
description: 13 pages, 8 figures, Accepted for publication in MNRAS
OpenAIRE Week: General Assembly Panel: European, National, International alignment
Creators: name: Shearer, Kathleen
name: Song, Sa-Kwang
name: Amaro, Bianca
name: Lasou, Pierre
name: Oaiya, Omo
name: Fazekas-Paragh, Judit
Publisher: name: Zenodo
Year: 2020
Subjects: OpenAIRE
Open Science
Open Science Policies
Open Science Infrastructures
International alignment

description: Presentations during the panel session of the OpenAIRE Week, General Assembly. The panel examined the shared building blocks for Open Science, around policy and infrastructure and identified key takeaways.
Legacy effect of microplastics on plant–soil feedbacks
Creators: name: Lozano, Yudi M.
name: Rillig, Matthias C.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: microplastic shape
subject: plant–soil interactions
subject: plant biomass
subject: polymer type
subject: root morphological traits
subject: soil inocula
subject: 500 Naturwissenschaften und Mathematik::580 Pflanzen (Botanik)::580 Pflanzen (Botanik)

description: Microplastics affect plants and soil biota and the processes they drive. However, the legacy effect of microplastics on plant–soil feedbacks is still unknown. To address this, we used soil conditioned from a previous experiment, where Daucus carota grew with 12 different microplastic types (conditioning phase). Here, we extracted soil inoculum from those 12 soils and grew during 4 weeks a native D. carota and a range-expanding plant species Calamagrostis epigejos in soils amended with this inoculum (feedback phase). At harvest, plant biomass and root morphological traits were measured. Films led to positive feedback on shoot mass (higher mass with inoculum from soil conditioned with microplastics than with inoculum from control soil). Films may decrease soil water content in the conditioning phase, potentially reducing the abundance of harmful soil biota, which, with films also promoting mutualist abundance, microbial activity and carbon mineralization, would positively affect plant growth in the feedback phase. Foams and fragments caused positive feedback on shoot mass likely via positive effects on soil aeration in the conditioning phase, which could have increased mutualistic biota and soil enzymatic activity, promoting plant growth. By contrast, fibers caused negative feedback on root mass as this microplastic may have increased soil water content in the conditioning phase, promoting the abundance of soil pathogens with negative consequences for root mass. Microplastics had a legacy effect on root traits: D. carota had thicker roots probably for promoting mycorrhizal associations, while C. epigejos had reduced root diameter probably for diminishing pathogenic infection. Microplastic legacy on soil can be positive or negative depending on the plant species identity and may affect plant biomass primarily via root traits. This legacy may contribute to the competitive success of range-expanding species via positive effects on root mass (foams) and on shoot mass (PET films). Overall, microplastics depending on their shape and polymer type, affect plant–soil feedbacks.
Behavioral development in the absence of neural activity: effects of chronic immobilization on amphibian embryos
Creators: name: Haverkamp, L. J.
name: Oppenheim, R. W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: Embryos of Xenopus laevis and Ambystoma mexicanum were continually immobilized from premotile stages of development to stages at which normally reared embryos were swimming well. Immobilization was achieved through exposure to solutions of chloretone, lidocaine, or alpha- bungarotoxin. At a number of stages after recovery from the drugs, spontaneous and stimulated behaviors were extensively quantified. Immobilization of Ambystoma embryos resulted in temporary defects in musculoskeletal development. In contrast, treated Xenopus embryos could not be distinguished from controls by simple visual observation within minutes to hours after removal from the drug solutions. Quantifications of behavior revealed, however, a transient period of 24–48 hr during which treated embryos exhibited consistently reduced measures of stimulated swimming, while showing an increase in frequency of spontaneous movements. Detailed behavioral testing could detect no permanent effects of chronic immobilization in either species after this initial period of recovery. The results are discussed in reference to the classic works of Harrison (1904), Carmichael (1926, 1927), and Matthews and Detwiler (1926).
(1432) Phillis [Cary]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
KARL FREIHERR VON FRITSCH (1838 -1906): Wegbereiter des geologischen Profils an der Martin-Luther-Universität in Halle: KARL FREIHERR VON FRITSCH (1838 -1906): Pioneer of the Model Geological Profile, Martin Luther University, Halle
Creators: name: Reichstein, Manfred
Publisher: name: Hallesches Jahrbuch für Geowissenschaften
Year: 1998
Subjects: subject: 000

description: Zu Beginn des 20. Jahrhunderts war FREIHERR VON FRITSCH als Direktor des Mineralogischen Instituts und Präsident der LEOPOLDINA in Halle eine hochangesehene Persönlichkeit. Als sein Hauptverdienst wird die Erweiterung des ehemaligen Mineralienkabinetts zur damals umfangreichsten Gesteins- und Fossilsammlung in Mitteldeutschland angesehen. Angeregt durch die Landwirtschaftler unter Professor Julius KÜHN schuf er in deren Institutsgelände ein einst hochgeschätztes „Geologisches Profil" von 30 Metern Länge für Lehrzwecke, das aus über 200 verschiedenen Natursteinen zusammengesetzt, einen informativen Gang durch die Erdgeschichte erlaubte. Von diesem auch künstlerisch anspruchsvoll gestalteten Werk sind heute nur noch Spuren erhalten. Für die Pflege bzw. Restaurierung dieses in Vergessenheit geratenen kulturellen Erbgutes werden erste Vorschläge unterbreitet.
description: At the beginning of the 20th century FREIHERR VON FRITSCH was Director of the "Mineralogical Institute" and President of the Leopoldina Academy, making him very well-known in Halle. The enlargement of the old "Mineral Cabinet" by new rock and fossil samples is thought to have been his main task for the geoscience branch of the University in Central Germany. Inspired by Professor Juuus KÜHN, his colleague in agricultural science, he constructed a highly-prized "Geological Profile" of 30 m length for educational purposes, which had over 200 examples of natural rock settings, and which provided an informative depiction of the history of the Earth. lt would seem tobe our duty to preserve and/or restore this forgotten cultural heritage.
Characteristics and distribution of high- and low-affinity alpha bungarotoxin binding sites in the rat hypothalamus
Creators: name: Michels, K. M.
name: Hayward, J. N.
name: Libber, M. T.
name: Meeker, R. B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: Afin d'évaluer l'importance du ligand de l'I-αBTX dans l'hypothalamus et la présence possible de récepteurs nicotiniques, des études immunocytochimiques et autoradiographiques ont été réalisées. Les résultats suggèrent que ces sites de fixation ont un rôle important dans l'organisation fonctionnelle du système neurosécréteur des vasopressine et oxytocine.
Suppl. File 6 from Within-population variability in a moth sex pheromone blend, part 2: selection towards fixation.
Creators: name: Groot, Astrid T.
name: Wijk, Michiel Van
name: Villacis-Perez, Ernesto
name: Kuperus, Peter
name: Schöfl, Gerhard
name: Veldhuizen, Dennis Van
name: Heckel, David G.
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology

description: Gels showing the intron-size polymorphism of the second intron of LPAQ delta-11-desaturase.
Mitteilungen aus dem Institut
Creators: name: (:Unkn) Unknown
Publisher: name: Hallesches Jahrbuch für Geowissenschaften
Year: 1998
Subjects: subject: 000

description: Festkolloquium zum 60. Geburtstag von Dr. Gerhard Beutler Prof. (em.) Dr. habil. Manfred Reichstein wurde 70 Jahre alt 50. Todestag von Prof. Johannes Weigelt International Symposium on the Epicontinental Triassic
Executive summary of case study results (Deliverable D6.3)
Creators: name: Balázs, Katalin
name: Toth, Peter
name: Centeri, Csaba
name: Podmaniczky, Laszlo
name: Schwarz, Gerald
name: Wolff, Anne
name: Bergschmidt, Angela
name: Offermann, Frank
name: Osterburg, Bernhard
name: Aalders, Inge
name: Miller, David
name: Gimona, Alessandro
name: Morrice, Jane
name: Vlahos, George
name: Smyrniotopoulou, Alexandra
name: Artell, Janne
name: Aakkula, Jyrki
name: Toikkanen, Heini
name: Povellato, Andrea
name: Longhitano, Davide
name: Lasorella, Valentina
name: Morkvenas, Zymantas
name: Navickas, Kestutis
name: Gulbinas, Justas
name: Jefanovas, Aivaras
Publisher: name: Zenodo
Year: 2015

description: The main aim of the report is to provide an overview of the results of the case studies testing a range of indicators and methods for the evaluation of rural development measures and Rural Development Programme (RDP) impacts on environmental public goods, and to derive recommendations for adjustments to the methodological framework in WP3 to WP5 as a basis for the methodological handbook (Morkvenas et al., 2015).
Politicised nexus thinking in practice
Creators: name: Moss, Timothy
name: Hüesker, Frank
Publisher: name: Humboldt-Universität zu Berlin
Year: 2017
Subjects: subject: local politics
subject: nexus
subject: renewable energy
subject: urban infrastructure
subject: wastewater
subject: 地方政治
subject: 联系
subject: 可再生能源
subject: 城市基础设施
subject: 废水
subject: 551 Geologie, Hydrologie, Meteorologie
subject: 333.7 Natürliche Resourcen, Energie und Umwelt
subject: 320 Politikwissenschaft

description: Infrastructures are key interfaces of urban resource use, connecting production to consumption, cities to their hinterland and energy to water and land use. They have, however, received scant attention in debates on nexus thinking in general, and the urban nexus in particular. Drawing on an emergent critical literature on the nexus in urban studies and science and technology studies, this article examines practices of (attempted) inter-sectoral infrastructure integration at the interface of urban wastewater treatment and regional energy provision in Germany. It analyses the nexus approaches and experiences of eight German cities / city-regions as so-called ‘flexibility providers’ in regional energy markets for electricity, gas and heating. It demonstrates how the practices of wastewater utilities operating in energy markets involve far more than technical adaptation, requiring in addition a major reordering of existing material, spatial and institutional configurations to both wastewater and energy systems. This is proving a deeply political process with important implications for our understanding of socio-technical transitions at the water-energy nexus.
description: 基础设施是城市资源利用的关键连接口, 将生产连接至消费, 城市连接至内陆腹地, 能源连接至水和土地利用。然而, 在学界总体关于“关系”(nexus) 思维和具体关于城市关系的讨论中, 基础设施鲜受关注。本文借鉴城市研究和科技研究中新涌现出的关于“关系”的关键文献, 考察了德国城市污水处理与区域能源供应交接地带的部门间基础设施整合实践。我们选取了德国八个在电力、燃气和暖气供应的区域能源市场中以所谓“灵活供应商”身份出现的城市/城市地区, 分析了其“关系”进路和经历。分析表明, 在能源市场运行的污水处理设施, 其所做远远不止是技术调整适应, 另外还要对废水和能源系统的现有材料、空间和机构配置进行大幅重整。研究证明, 这是一个深远的政治进程, 对我们理解水能源关系中的社会技术转型具有重要意义。
Differences in transmitter release and number of nerve terminals per motoneuron between two frog muscles
Creators: name: Weakly, J. N.
name: Yao, Y. M.M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: Recent studies suggest that the number of nerve terminals maintained per motoneuron and perhaps other motoneuron properties (Grinnell and Herrera, 1980a; Grinnell and Trussell, 1983) influence transmitter release. We have examined, in detail, the structure and function of motoneurons innervating two different twitch muscles, the sartorius and the ext. long. dig. IV (e.l.d.) in the adult frog using histochemical and electrophysiological techniques. These studies were undertaken with a view towards learning whether differences in the number of nerve terminals per motoneuron were correlated with differences in transmitter release between motoneurons innervating these two muscles. Moreover, these studies provide detailed, quantitative data that are a necessary prerequisite for carrying out additional studies to examine the possible influence of muscle on transmitter release properties. In low Ca2+-high Mg2+ Ringer's solution, mean quantal content (m) and miniature end-plate potential (MEPP) frequency were larger at sartorius than at e.l.d. end-plates. The mean length of nerve terminals was also found to be greater in sartorius than in e.l.d. muscles. When release was normalized for the difference in terminal length, m remained larger in the sartorius, whereas MEPP frequency in the two muscles was similar. Cell bodies of individual sartorius motoneurons were greater in cross-sectional area and maintained approximately 5.6-fold greater aggregate length of nerve terminals per motoneuron than did e.l.d. motoneurons. This greater aggregate length of nerve terminal contact with their respective target muscles is primarily a result of a greater number of nerve terminals supported by sartorius than by e.l.d. motoneurons.( TRUNCATED AT 250 WORDS)
Synthesis and antimicrobial activity of aminoalkyl resveratrol derivatives inspired by cationic peptides
Creators: name: Cebrián, Rubén
name: Lucas, Ricardo
name: Fernández-Cantos, María Victoria
name: Slot, Koen
name: Peñalver, Pablo
name: Martínez-García, Marta
name: Párraga-Leo, Antonio
name: de Paz, María Violante
name: García, Federico
name: Kuipers, Oscar P.
name: Morales, Juan Carlos
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Antimicrobial resistance is a global concern, far from being resolved. The need of new drugs against new targets is imminent. In this work, we present a family of aminoalkyl resveratrol derivatives with antibacterial activity inspired by the properties of cationic amphipathic antimicrobial peptides. Surprisingly, the newly designed molecules display modest activity against aerobically growing bacteria but show surprisingly good antimicrobial activity against anaerobic bacteria (Gram-negative and Gram-positive) suggesting specificity towards this bacterial group. Preliminary studies into the action mechanism suggest that activity takes place at the membrane level, while no cross-resistance with traditional antibiotics is observed. Actually, some good synergistic relations with existing antibiotics were found against Gram-negative pathogens. However, some cytotoxicity was observed, despite their low haemolytic activity. Our results show the importance of the balance between positively charged moieties and hydrophobicity to improve antimicrobial activity, setting the stage for the design of new drugs based on these molecules.
Machine Learning for Quantum Mechanical Properties of Atoms in Molecules
Creators: name: Rupp, Matthias
name: Ramakrishnan, Raghunathan
name: von Lilienfeld, O. Anatole
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We introduce machine learning models of quantum mechanical observables of atoms in molecules. Instant out-of-sample predictions for proton and carbon nuclear chemical shifts, atomic core level excitations, and forces on atoms reach accuracies on par with density functional theory reference. Locality is exploited within non-linear regression via local atom-centered coordinate systems. The approach is validated on a diverse set of 9k small organic molecules. Linear scaling of computational cost in system size is demonstrated for saturated polymers with up to sub-mesoscale lengths.
SMC 2009: 6th Sound and Music Computing Conference | 23 - 25 | July Casa da Música | Porto
Creators: name: Makelberge, Nicolas
name: Guerreiro, Ricardo
name: Joaquim, Vitor
Publisher: name: Journal of Science and Technology of the Arts
Year: 2010

description: Journal of Science and Technology of the Arts, v. 2 n. 1 (2010)
Different synaptic channel kinetics in sympathetic B and C neurons of the bullfrog
Creators: name: Marshall, L. M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: Sympathetic ganglia of the frog contain two types of principal neurons, B and C cells, which are innervated by two distinct classes of cholinergic preganglionic axons, B and C fibers. This study examined and compared the kinetics of nicotinic ACh-gated channels that produce the fast excitatory postsynaptic currents (EPSCs) in B and C cells. Neurons were identified and voltage-clamped at -50 mV, 22 degrees C. The EPSC decayed as a single exponential for both cell types, but the decay time constants differed considerably; 10.2 +/- 2.3 msec (mean +/- SD) for C cells and 5.5 +/- 1.1 msec for B cells. Analysis of ACh- induced membrane current fluctuations revealed spectra that fit single- Lorentzian functions and gave estimates of the mean channel open time of 9.8 +/- 2.0 msec and 5.2 +/- 0.9 msec for C and B cells, respectively. Thus, the clear difference in EPSC decay rate for these two types of ganglion cells is most likely due to the differences in the mean lifetimes of their synaptic channels.
(1433) Henry Seaton
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Epidemic spread of Erysiphe corylacearum in Europe – first records from Germany
Creators: name: Beenken, Ludwig
name: Kruse, Julia
name: Schmidt, Anke
name: Braun, Uwe
Publisher: name: Schlechtendalia
Year: 2022
Subjects: subject: 000

description: Beenken, L., Kruse, J., Schmidt, A. & Braun, U. 2022: Epidemische Ausbreitung von Erysiphecorylacearumin Europa – erste Nachweise in Deutschland. Schlechtendalia 39: 112–118. Erysiphe corylacearum, ein Asiatischer Corylus-Mehltau, wurde in den letzten Jahren in Europa eingeschleppt. In jüngster Zeit wurde das Vorkommen von E. corylacearum auch für Deutschland nachgewiesen. Phylogenie, Taxonomie, Wirtsspektrum, Verbreitung und die epidemische Ausbreitung dieser Art in Europa werden kurz diskutiert. Die Konidienkeimung wird imDetail beschrieben und abgebildet. Die Identifizierung wurde molekular durch Sequenzierung der ITS-Region bestätigt
description: Beenken, L., Kruse, J., Schmidt, A. & Braun, U. 2022: Epidemic spread of Erysiphe corylacearum in Europe – first records from Germany. Schlechtendalia 39: 112–118. Erysiphe corylacearum, an Asian Corylus powdery mildew, has been introduced in Europe in recent years. Recently, the occurrence of E. corylacearum has also been confirmed for Germany. Phylogeny, taxonomy, host range, distribution, and the epidemic spread of this species in Europe are briefly discussed. The conidial germination pattern is described and illustrated in detail. The identification was confirmed molecularly by sequencing the ITS region.
Potent carbonic anhydrase I, II, IX and XII inhibition activity of novel primary benzenesulfonamides incorporating bis-ureido moieties
Creators: name: Tekeli, Tuba
name: Akocak, Suleyman
name: Petreni, Andrea
name: Lolak, Nebih
name: Çete, Servet
name: Supuran, Claudiu T.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: A novel series of twelve aromatic bis-ureido-substituted benzenesulfonamides was synthesised by conjugation of aromatic aminobenzenesulfonamides with aromatic bis-isocyanates. The obtained bis-ureido-substituted derivatives were tested against four selected human carbonic anhydrase isoforms (hCA I, hCA II, hCA IX and hCA XII). Most of the new compounds showed an effective inhibitory profile against isoforms hCA IX and hCA XII, also having some selectivity with respect to hCA I and hCA II. The inhibition constants of these compounds against isoforms hCA IX and XII were in the range of 6.73–835 and 5.02–429 nM, respectively. Since hCA IX and hCA XII are important drug targets for anti-cancer/anti-metastatic drugs, these effective inhibitors reported here may be considered of interest for cancer related studies in which these enzymes are involved.
Kainic acid alters the metabolism of Met5-enkephalin and the level of dynorphin A in the rat hippocampus
Creators: name: Grimes, L.
name: Hong, J. S.
name: Yoshikawa, K.
name: Obie, J.
name: Kanamatsu, T.
name: Sabol, S.
name: McGinty, J. F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: Male Fischer-344 rats were given a single intrastriatal injection of kainic acid (KA; 1 microgram/rat), which caused recurrent motor seizures lasting 3-6 hr. During the convulsive period, native Met5-enkephalin-like (ME-LI) and dynorphin A (1-8)-like (DYN-LI) immunoreactivities in hippocampus decreased by 31 and 63%, respectively. By 24 hr after dosing, the hippocampal opioid peptides had returned to control levels, and by 48 hr ME-LI had increased 270% and DYN-LI 150%. Immunocytochemical analysis revealed that ME-LI and Leu5-enkephalin-like (LE-LI) immunostaining in the mossy fibers of dentate granule cells and the perforant-temporoammonic pathway had decreased visibly by 6 hr and had increased markedly by 48 hr following KA. A visible decrease in DYN-LI in mossy fiber axons within 6 hr was followed by a substantial increase by 48 hr. To determine whether the increases in hippocampal ME-LI reflected changes in ME biosynthesis, levels of mRNA coding for preproenkephalin (mRNAenk) and cryptic ME-LI cleaved by enzyme digestion from preproenkephalin were measured. Following the convulsive period (6 hr), mRNAenk was 400% of control, and by 24 hr, cryptic ME-LI was 300% of control. Increases in native and cryptic ME-LI and in mRNAenk were also noted in entorhinal cortex, but not in hypothalamus or uninjected striatum. Our data suggest that KA-induced seizures cause an increase in ME release, followed by a compensatory increase in ME biosynthesis in the hippocampus and entorhinal cortex.
Image, ritual and urban form: Porto in the 16th Century
Creators: name: Afonso, José Ferrão
Publisher: name: Journal of Science and Technology of the Arts
Year: 2010

description: In the early 17th Century, the Spanish painter Francisco Pacheco railed against his apprentices, telling them that the image should stand out of the picture. The topic was the one most debated in the art of the Counter-Reformation, whose main directives, outlined in the Council of Trent, would be put in motion simultaneously with urban "Christianisation". They presupposed a social contract, established between producer and receiver, implying maximum clarity of the message, which involved an ambiguous grey area that would be reserved for the outside of the focus. In painting, which sacrificed everything that was incidental or extraneous to the story, showing the essential and neglecting the accessory, the binary radicalism of the concept became more explicit, through the Caravaggian illumination or in the case above, the Spanish tenebrism of Velásquez, to whom Pacheco's admonition was addressed. In our Doctoral Thesis presented at the School of Architecture in Barcelona, we sought to demonstrate that the Plastic Arts were not the only field for the application of Luminist principles. In this article we aim to summarise this thesis by exposing the important relationships between image, ritual and urban form in 16th Century Porto, after a time, therefore, the late Middle Ages, which Huizinga classified as deeply iconophile , in which image and ritual were put at the service of the reformulation of a State becoming increasingly centralised and interventionist, whose action extended to the sphere of the Church: with King João II, and especially King Manuel I, the Crown was an active sponsor of religious reform that was pursued with redoubled energy and systematisation, from the reign of "the Pious", then already within the political system of close bilateral cooperation that was designated the Confessional State. We therefore believe that this type of approach to anthropological and symbolic components, which seeks to take into account the increasing importance that is given in contemporary research on the city's history, can be very fruitful.
description: Journal of Science and Technology of the Arts, v. 2 n. 1 (2010)
Novel Glu-based pyrazolo[3,4-d]pyrimidine analogues: design, synthesis and biological evaluation as DHFR and TS dual inhibitors
Creators: name: Mahnashi, Mater
name: Alshahrani, Mohammed Merae
name: Al Ali, Amer
name: Asiri, Abdulaziz
name: Abou-Salim, Mahrous A.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Cell Biology
Neuroscience
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer

description: A novel series of multifunctional pyrazolo[3,4-d]pyrimidine-based glutamate analogs (6a–l and 7a,b) have been designed and synthesized as antifolate anticancer agents. Among the tested compounds, 6i exhibited the most potent anti-proliferative activity towards NSCLC, CNS, Ovarian, Prostate, Colon, Melanoma, Breast, and Renal cancers with good to weak cytostatic activity and non-lethal actions. 6i demonstrated higher selectivity for cancer than normal cells. 6i could significantly increase the accumulation of S-phase cells during the cell cycle distribution of cancer cells with high potency in the induction of apoptosis. The results unveiled that 6i probably acts through dual inhibition of DHFR and TS enzymes (IC50 = 2.41 and 8.88 µM, correspondingly). Docking studies of 6i displayed that N1-p-bromophenyl and C3-Methyl groups participate in substantial hydrophobic interactions. The drug-likeness features inferred that 6i met the acceptance criteria of Pfizer. Taking together, 6i could be a promising prototype for further optimization as an effective anticancer drug.
Center vortices as composites of monopole fluxes
Creators: name: Deldar, Sedigheh
name: Nejad, Seyed Mohsen Hosseini
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the relation between the flux of a center vortex obtained from the center vortex model and the flux formed between monopoles obtained from the Abelian gauge fixing method. Motivated by the Monte Carlo simulations which have shown that almost all monopoles are sitting on the top of vortices, we construct the fluxes of center vortices for $SU(2)$ and $SU(3)$ gauge groups using fractional fluxes of monopoles. Then, we compute the potentials in the fundamental representation induced by center vortices and fractional fluxes of monopoles. We show that by combining the fractional fluxes of monopoles one can produce the center vortex fluxes for $SU(3)$ gauge group in a "center vortex model". Comparing the potentials, we conclude that the fractional fluxes of monopoles attract each other.
description: 7 pages, 6 figures, Contribution to the conference "Quark Confinement and the Hadron Spectrum XI", Saint Petersburg, Russia, 7-12 Sep 2014
Cinematography and television: differences and similarites
Creators: name: Nazareth, Adriano
Publisher: name: Journal of Science and Technology of the Arts
Year: 2010

description: Television and Cinema present specific behaviour and language in relation to reality. If film focuses on its proximity to artistic practices, and this reflects the viewer’s relationship with the film, television, in turn, seeks in directness or the transposition of the real to the imaginary, the key to its success, the audience. We all see the possibilities that television has for viewers. Even those most aware of the various con- straints, and who claim themselves to be not influenced, come under the hypnotic power of the television screen. The quality of the programming continues to decline, succumbing to the claim that television channels have to get into the audience “ratings”.
description: Journal of Science and Technology of the Arts, v. 2 n. 1 (2010)
Cellular automata simulations of field scale flaming and smouldering wildfires in peatlands
Creators: name: Purnomo, Dwi Marhaendro Jati
Publisher: name: Imperial College London
Year: 2022

description: In peatland wildfires, flaming vegetation can initiate a smouldering fire by igniting the peat underneath, thus, creating a positive feedback to climate change by releasing the carbon that cannot be reabsorbed by the ecosystem. Currently, there are very few models of peatland wildfires at the field-scale, hindering the development of effective mitigation strategies. This lack of models is mainly caused by the complexity of the phenomena, which involves 3-D spread and km-scale domains, and the very large computational resources required. This thesis aims to understand field-scale peatland wildfires, considering flaming and smouldering, via cellular automata, discrete models that use simple rules. Five multidimensional models were developed: two laboratory-scale models for smouldering, BARA and BARAPPY, and three field-scale models for flaming and smouldering, KAPAS, KAPAS II, and SUBALI. The models were validated against laboratory experiments and field data. BARA accurately simulates smouldering of peat with realistic moisture distributions and predicts the formation of unburned patches. BARAPPY brings physics into BARA and predicts the depth of burn profile, but needs 240 times more computational resources. KAPAS showed that the smouldering burnt area decreases exponentially with higher peat moisture content. KAPAS II integrates daily temporal variation of moisture content, and revealed that the omission of this temporal variation significantly underestimates the smouldering burnt area in the long term. SUBALI, the ultimate model of the thesis, integrates KAPAS II with BARA and considers the ground water table to predict the carbon emission of peatland wildfires. Applying SUBALI to Indonesia, it predicts that in El Niño years, 0.40 Gt-C in 2015 (literature said 0.23 to 0.51 Gt-C) and 0.16 Gt-C in 2019 were released, and 75% of the emission is from smouldering. This thesis provides knowledge and models to understand the spread of flaming and smouldering wildfires in peatlands, which can contribute to efforts to minimise the negative impacts of peatland wildfires on people and the environment, through faster-than-real-time simulations, to find the optimum firefighting strategy and to assess the vulnerability of peatland in the event of wildfires.
Luiz Costa: in commemoration of the fiftieth anniversary of his death
Creators: name: Beirão, Christine
name: Araújo, Henrique L. Gomes De
Publisher: name: Journal of Science and Technology of the Arts
Year: 2010

description: This text is dedicated to the commemoration of the fiftieth anniversary of the death of the composer, pianist and teacher Luiz Costa (S. Pedro do Monte de Fralães, 1879 – Porto, 1960). The preface begins by clarifying the meaning of commemoration as a ritual. The text is divided into two parts. The first, anthropologic in nature, undertakes the problems involved in the construction of the identity of Luiz Costa as a person and as an artist within the more general question of this construction emerging from the anthropological themes of birth, suffering, love and death. The second, musicological part demonstrates that events and circumstances in the life of an artist can leave their marks on his works. Some characteristic compositions of Luiz Costa are analysed with the intention to gain information about the mind and character of the man and the artist that he was.
description: Journal of Science and Technology of the Arts, v. 2 n. 1 (2010)
Compositional bowing of band energies and their deformation potentials in strained InGaAs ternary alloys: a first-principles study
Creators: name: Khomyakov, Petr A.
name: Luisier, Mathieu
name: Schenk, Andreas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Using first-principles calculations, we show that the conduction and valence band energies and their deformation potentials exhibit a non-negligible compositional bowing in strained ternary semiconductor alloys such as InGaAs. The electronic structure of these compounds has been calculated within the framework of local density approximation and hybrid functional approach for large cubic supercells and special quasi-random structures, which represent two kinds of model structures for random alloys. We find that the predicted bowing effect for the band energy deformation potentials is rather insensitive to the choice of the functional and alloy structural model. The direction of bowing is determined by In cations that give a stronger contribution to the formation of the In$_{x}$Ga$_{1-x}$As valence band states with $x\gtrsim 0.5$, compared to Ga cations.
description: 9 pages, 4 figures, and 2 tables
(1434) Edward Ambler Seaton
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Feasibility of improving risk stratification in the inherited cardiac conditions
Creators: name: Chow, Ji-Jian
Publisher: name: Imperial College London
Year: 2021

description: Fatal ventricular arrhythmias can occur in patients with Hypertrophic Cardiomyopathy, Brugada Syndrome and rarely in patients with normal cardiac investigations. Despite very different pathogeneses, we hypothesised that a common electrophysiological substrate precipitates these arrhythmias and could be used as a marker for risk stratification. In Chapter 3 of this thesis, we found that fewer than half the cardiac arrest survivors with Brugada Syndrome would have been offered prophylactic defibrillators based on current risk scoring, highlighting the need for better risk stratification. Our group previously used a commercially available 252-electrode vest which constructs ventricular electrograms onto a CT image of the heart to show exercise related differences in high-risk patients. In Chapter 4, we applied this method to Brugada patients, but could not reproduce prior results. Further investigation revealed periodic changes in activation patterns after exercise that could explain this discrepancy. An alternative matrix approach was developed to overcome this problem. Exercise induced conduction heterogeneity differentiated Brugada patients from unaffected controls, but not those surviving cardiac arrest. However, if considered alongside spontaneous type 1 ECG and syncope, inducible conduction heterogeneity markedly improved identification of Brugada cardiac arrest survivors. In Chapter 5 the method was shown to differentiate idiopathic ventricular fibrillation patients from those fully recovered from acute ischaemic cardiac arrest, implying a permanent electrophysiological abnormality. In Chapter 8, we showed prolonged mean local activation times and activation-recovery intervals in hypertrophic cardiomyopathy cardiac arrest survivors compared to those without previous ventricular arrhythmia. These metrics were combined into both logistic regression and support vector machine models to strongly differentiate the groups. We concluded that electrophysiological changes could identify cardiac arrest survivors in various cardiac conditions, but a single factor common pathway was not established. Prospective studies are required to determine if using these parameters could enhance current risk stratification for sudden death.
Untitled * Interactive generative installation for visual composition
Creators: name: Gomes, Joana Fernandes
Publisher: name: Journal of Science and Technology of the Arts
Year: 2010

description: The generative art changed our concepts of image and art. They are so embedded in they way we can create new visual artistic expression. This paper will present some ideas regarding generative art and introduce Untitled*, piece developed using those principles.
description: Journal of Science and Technology of the Arts, v. 2 n. 1 (2010)