cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The R521K polymorphism of EGFR influences the risk of colorectal cancer
Creators: name: Martinelli, Marcella
name: Ugolini, Giampaolo
name: Scapoli, Luca
name: Rivetti, Stefano
name: Lauriola, Mattia
name: Mattei, Gabriella
name: Rosati, Giancarlo
name: Montroni, Isacco
name: Manaresi, Alessio
name: Zattoni, Davide
name: Taffurelli, Mario
name: Solmi, Rossella
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: colorectal cancer; EGFR; HER2; HER3; polymorphism

description: In colorectal cancer (CRC) epidermal growth factor receptor (EGFR) family members (EGFR, HER2, HER3 and HER4) have been found frequently over-expressed. New therapies directed against EGFR have been developed in many human cancers. Unexpectedly, EGFR alterations could be good prognostic indicators, like in lung cancer, where an EGFR variant in non-smoker female patients is associated with higher survival after surgery and increases the efficiency of therapy based on EGFR inhibitors. The role of the genetic polymorphisms of the EGFR family members in colorectal cancer development has not been completely explored. In our preliminary study, three missense polymorphisms mapping in EGFR family members have been investigated in the peripheral blood of a small Italian sample size of 70 patients and 72 controls to verify if they could be considered CRC susceptibility factors. For the first time, the evidence of genotype association was found for the R521K EGFR polymorphism: the protective effect for this variant allele has been found to reduce the risk for colon cancer onset.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
title: Ð¡ÑÑÐ°ÑÐµÐ³Ð¸Ñ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÑÐ¾Ð·Ð½Ð¸ÑÐ½Ð¾Ð¹ ÑÐ¾ÑÐ³Ð¾Ð²Ð¾Ð¹ ÑÐµÑÐ¸ Â«TRUVORÂ» Ð² Ð¡ÐµÐ²ÐµÑÐ¾-ÐÐ°Ð¿Ð°Ð´Ð½Ð¾Ð¼ ÑÐµÐ³Ð¸Ð¾Ð½Ðµ
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ¸ÑÐ¾Ð½Ð¾Ð²Ð°, ÐÐ½Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÑÐ¾Ð·Ð½Ð¸ÑÐ½Ð°Ñ ÑÐ¾ÑÐ³Ð¾Ð²Ð»Ñ
ÑÐ¾Ð·Ð½Ð¸ÑÐ½Ð°Ñ ÑÐ¾ÑÐ³Ð¾Ð²Ð°Ñ ÑÐµÑÑ
Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸
Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ
ÑÑÑÐ°ÑÐµÐ³Ð¸Ñ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ ÑÐ¾Ð·Ð½Ð¸ÑÐ½Ð°Ñ ÑÐ¾ÑÐ³Ð¾Ð²Ð°Ñ ÑÐµÑÑ Â«TRUVORÂ» ÐÐÐ Â«Ð¡ÐÐÐÐ¯ÐÐÐ ÐÐÐ®Ð¡Â». Ð¦ÐµÐ»ÑÑ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¸ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÑÐ¾Ð·Ð½Ð¸ÑÐ½Ð¾Ð¹ ÑÐ¾ÑÐ³Ð¾Ð²Ð¾Ð¹ ÑÐµÑÐ¸ Â«TRUVORÂ». ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÐ¾Ð·Ð½Ð¸ÑÐ½Ð¾Ð¹ ÑÐµÑÐ¸ Â«TRUVORÂ», ÐµÐµ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾-ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ¸. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¾ Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸ÐµÐ¼ Ð°Ð½ÐºÐµÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ. ÐÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ñ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÐµ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ. Ð¡ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð° ÑÑÑÐ°ÑÐµÐ³Ð¸Ñ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÑÐ¾Ð·Ð½Ð¸ÑÐ½Ð¾Ð¹ ÑÐ¾ÑÐ³Ð¾Ð²Ð¾Ð¹ ÑÐµÑÐ¸ Â«TRUVORÂ». Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑ Ð¼ÐµÑ Ð¿Ð¾ ÐµÐµ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸. Ð ÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð½ÑÑ Ð¼ÐµÑ Ð¿ÑÐ¸Ð²ÐµÐ´ÐµÑ Ðº Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ ÑÐ¸ÑÑÐ¾Ð¹ Ð¿ÑÐ¸Ð±ÑÐ»Ð¸ ÑÐ¾Ð·Ð½Ð¸ÑÐ½Ð¾Ð¹ ÑÐ¾ÑÐ³Ð¾Ð²Ð¾Ð¹ ÑÐµÑÐ¸.
A Few Binary Star Puzzles for Roberto on the Occasion of His Birthday
Creators: name: Preston, George W.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Radial velocity observations accumulated during the past 16 years are used to derive a preliminary orbit for the CEMP star CS 22881-036. The velocity amplitude is very small. No velocity variation is found for three additional CEMP stars observed over roughly the same time interval. Searches for companions of two CEMP double-lined spectroscopic binaries and of the RR Lyrae star TY Gruis are reviewed. A disparity between the period distribution of disk carbon-star binaries and that of their parent population of normal binaries can be attributed qualitatively to a decline in accreted mass with increasing binary separation. Finally, possible reasons for failure to find expected companions of CEMP stars are discussed.
description: 12 pages, 5 figures, Gallino Birthday Workshop
Squeezing the Arimoto-Blahut algorithm for faster convergence
Creators: name: Yu, Yaming
Publisher: name: arXiv
Year: 2009
Subjects: subject: Information Theory (cs.IT)
subject: Computation (stat.CO)
subject: FOS: Computer and information sciences

description: The Arimoto--Blahut algorithm for computing the capacity of a discrete memoryless channel is revisited. A so-called ``squeezing'' strategy is used to design algorithms that preserve its simplicity and monotonic convergence properties, but have provably better rates of convergence.
title: ÐÐµÑÐ°Ð»Ð»Ð¾ÑÐµÐ¶ÑÑÐ¸Ðµ ÑÑÐ°Ð½ÐºÐ¸. ÐÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð³Ð¸Ð´ÑÐ¾ÑÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÑÑÑÐ¸Ñ Ð¼ÐµÑÐ°Ð»Ð»Ð¾ÑÐµÐ¶ÑÑÐ¸Ñ ÑÑÐ°Ð½ÐºÐ¾Ð² Ð¸ ÑÑÐ°Ð½Ð¾ÑÐ½ÑÑ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ¾Ð²
title: Ð¼ÐµÑÐ¾Ð´Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐºÐ°Ð·Ð°Ð½Ð¸Ñ
titleType: Subtitle
Creators: name: ÐÑÐ½Ð´ÑÑ, ÐÐ¸ÑÐ°Ð¸Ð»
Publisher: name: ÐÐ·Ð´-Ð²Ð¾ ÐÐ¾Ð»Ð¸ÑÐµÑÐ½. ÑÐ½-ÑÐ°
Year: 2009
Subjects: ÐÐµÑÐ°Ð»Ð»Ð¾ÑÐµÐ¶ÑÑÐ¸Ðµ ÑÑÐ°Ð½ÐºÐ¸

description: Ð¡Ð¾Ð¾ÑÐ²ÐµÑÑÑÐ²ÑÑÑ Ð´ÐµÐ¹ÑÑÐ²ÑÑÑÐµÐ¼Ñ ÑÑÐµÐ±Ð½Ð¾Ð¼Ñ Ð¿Ð»Ð°Ð½Ñ ÐÐÐ¤, Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½Ðµ Â«Ð Ð°ÑÑÐµÑ Ð¸ ÐºÐ¾Ð½ÑÑÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÑÑÐ°Ð½ÐºÐ¾Ð²Â» ÑÐ¸ÐºÐ»Ð° ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½ÑÑ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½, ÑÑÑÐ°Ð½Ð°Ð²Ð»Ð¸Ð²Ð°ÐµÐ¼ÑÑ Ð¡Ð¾Ð²ÐµÑÐ¾Ð¼ Ð²ÑÐ·Ð° (ÑÐ°ÐºÑÐ»ÑÑÐµÑÐ°), Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Ð¼Ð°Ð³Ð¸ÑÑÑÐ¾Ð² Â«ÐÐµÑÐ°Ð»Ð»Ð¾ÑÐµÐ¶ÑÑÐ¸Ðµ ÑÑÐ°Ð½ÐºÐ¸Â». Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð²Ð¾Ð¿ÑÐ¾ÑÑ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð½Ð°Ð¸Ð±Ð¾Ð»ÐµÐµ Ð¿ÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ð½ÑÑ Ð·Ð°Ð¼ÐºÐ½ÑÑÑÑ Ð³Ð¸Ð´ÑÐ¾ÑÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÑÑÑÐ¸Ñ (ÐÐ¡Ð) Ñ Ð´ÑÐ¾ÑÑÐµÐ»ÑÐ½Ð¾Ð¹ ÑÑÐµÐ¼Ð¾Ð¹ ÑÐµÐ³ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð´Ð»Ñ Ð¿Ð¾Ð´Ð²Ð¸Ð¶Ð½ÑÑ ÑÐ·Ð»Ð¾Ð² Ð¼ÐµÑÐ°Ð»Ð»Ð¾ÑÐµÐ¶ÑÑÐ¸Ñ ÑÑÐ°Ð½ÐºÐ¾Ð² Ð¸ ÑÑÐ°Ð½Ð¾ÑÐ½ÑÑ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ¾Ð². ÐÐ¾ÐºÐ°Ð·Ð°Ð½Ð° Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ° Ð´Ð»Ñ Ð¾ÑÐµÐ½ÐºÐ¸ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÐºÐ°ÑÐµÑÑÐ²Ð°, Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð½Ð°Ñ Ð½Ð° Ð°Ð¿Ð¿Ð°ÑÐ°ÑÐµ ÑÐµÐ¾ÑÐ¸Ð¸ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐµÐ³ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ. ÐÑÐ¸Ð²ÐµÐ´ÐµÐ½Ñ Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼Ñ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð¼Ð¾Ð´ÐµÐ»Ð¸, ÑÐ°ÑÑÐµÑÐ° Ð°Ð¼Ð¿Ð»Ð¸ÑÑÐ´Ð½Ð¾-ÑÐ°ÑÑÐ¾ÑÐ½ÑÑ Ð¸ ÑÐ°Ð·Ð¾ÑÐ°ÑÑÐ¾ÑÐ½ÑÑ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº ÐÐ¡Ð, Ð¿ÐµÑÐµÑÐ¾Ð´Ð½ÑÑ Ð¿ÑÐ¾ÑÐµÑÑÐ¾Ð² Ð¿ÑÐ¸ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð²ÑÐ¾Ð´Ð½ÑÑ Ð²Ð¾Ð·Ð´ÐµÐ¹ÑÑÐ²Ð¸ÑÑ. ÐÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ñ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² Ð´Ð½ÐµÐ²Ð½Ð¾Ð¹ Ð¸ Ð²ÐµÑÐµÑÐ½ÐµÐ¹ ÑÐ¾ÑÐ¼ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ Ð¿Ð¾ ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÐ¸ 151002 Â«ÐÐµÑÐ°Ð»Ð»Ð¾Ð¾Ð±ÑÐ°Ð±Ð°ÑÑÐ²Ð°ÑÑÐ¸Ðµ ÑÑÐ°Ð½ÐºÐ¸ Ð¸ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÑÂ» Ð¿ÑÐ¸ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ð¸ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÐ°Ð±Ð¾Ñ, ÐºÑÑÑÐ¾Ð²Ð¾Ð³Ð¾ Ð¸ Ð´Ð¸Ð¿Ð»Ð¾Ð¼Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ, ÐÐÐ  Ð¸ ÐÐÐÐÐ , ÑÐ°Ð¼Ð¾ÑÑÐ¾ÑÑÐµÐ»ÑÐ½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð¸ Ð´Ñ.
description: ÐÐµÑÐ°ÑÐ°ÐµÑÑÑ Ð¿Ð¾ ÑÐµÑÐµÐ½Ð¸Ñ ÑÐµÐ´Ð°ÐºÑÐ¸Ð¾Ð½Ð½Ð¾-Ð¸Ð·Ð´Ð°ÑÐµÐ»ÑÑÐºÐ¾Ð³Ð¾ ÑÐ¾Ð²ÐµÑÐ° Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¾Ð³Ð¾ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑÐ°.
title: ÐÐµÑÐ¾Ð´Ñ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð´Ð°Ð½Ð½ÑÑ ÑÑÐµÐ´ÑÑÐ²Ð°Ð¼Ð¸ R Ð¸ Ð¡Ð£ÐÐ MS SQL Server
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: ÐÐ°ÑÑÐ»ÑÐ´Ð°, ÐÐ¾Ð»Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: ÐÐ°Ð·Ñ Ð´Ð°Ð½Ð½ÑÑ
ÐÐµÐ¹ÑÐ¾Ð½Ð½ÑÐµ ÑÐµÑÐ¸
ÐÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐ·ÑÐºÐ¸
Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð´Ð°Ð½Ð½ÑÑ
ÐºÐ»Ð°ÑÑÐµÑÐ¸Ð·Ð°ÑÐ¸Ñ
data mining
clustering

description: ÐÐ°ÑÑÐ¾ÑÑÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¼ÐµÑÐ¾Ð´Ð°Ð¼ Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð´Ð°Ð½Ð½ÑÑ ÑÑÐµÐ´ÑÑÐ²Ð°Ð¼Ð¸ ÑÐ·ÑÐºÐ° R Ð¸ Ð¡Ð£ÐÐ SQL Server. Ð Ð°Ð±Ð¾ÑÐ° ÑÐ¾ÑÑÐ¾Ð¸Ñ Ð¸Ð· Ð²Ð²ÐµÐ´ÐµÐ½Ð¸Ñ, ÑÑÐµÑ ÑÐ°Ð·Ð´ÐµÐ»Ð¾Ð², Ð·Ð°ÐºÐ»ÑÑÐµÐ½Ð¸Ñ. ÐÐ¾ Ð²Ð²ÐµÐ´ÐµÐ½Ð¸Ð¸ Ð¾ÑÑÐ°Ð¶ÐµÐ½Ð° Ð°ÐºÑÑÐ°Ð»ÑÐ½Ð¾ÑÑÑ Ð·Ð°Ð´Ð°ÑÐ¸ Ð¸ Ð¾Ð¿Ð¸ÑÐ°Ð½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸Ñ Ðº ÑÐ°Ð±Ð¾ÑÐµ. Ð Ð¿ÐµÑÐ²Ð¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð¾Ð±Ð·Ð¾Ñ Ð°Ð½Ð°Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð·Ð°Ð´Ð°Ñ Ð² ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð¿Ð¾ÑÑÐ°Ð½Ð¾Ð²ÐºÐ°Ñ Ð¸ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ð¸Ñ ÑÐµÑÐµÐ½Ð¸Ñ. ÐÑÐ»Ð¸ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÐ»ÐµÐ´ÑÑÑÐ¸Ðµ Ð·Ð°Ð´Ð°ÑÐ¸: Ð¿Ð¾Ð¸ÑÐº Ð°ÑÑÐ¾ÑÐ¸Ð°ÑÐ¸Ð¹, ÐºÐ»Ð°ÑÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ñ, ÐºÐ»Ð°ÑÑÐµÑÐ¸Ð·Ð°ÑÐ¸Ñ, Ð°Ð½Ð°Ð»Ð¸Ð· Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÑ ÑÑÐ´Ð¾Ð², Ð²Ð¸Ð·ÑÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð². ÐÐ¾ Ð²ÑÐ¾ÑÐ¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð»Ð°ÑÑ ÑÐ°Ð±Ð¾ÑÐ° Ñ ÑÐµÐ»ÑÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ Ð±Ð°Ð·Ð¾Ð¹ Ð´Ð°Ð½Ð½ÑÑ ÑÑÐµÐ´ÑÑÐ²Ð°Ð¼Ð¸ R Ð¸ MS SQL Server. Ð ÑÑÐµÑÑÐµÐ¹ Ð³Ð»Ð°Ð²Ðµ Ð±ÑÐ»Ð° Ð¿ÑÐ¾Ð´ÐµÐ»Ð°Ð½Ð° ÑÐ°Ð±Ð¾ÑÐ° Ñ Ð¿Ð»Ð¾ÑÐ¾ ÑÑÑÑÐºÑÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¼Ð¸ Ð´Ð°Ð½Ð½ÑÐ¼Ð¸, Ð° Ð¸Ð¼ÐµÐ½Ð½Ð¾, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐ¾Ð½Ð°Ð»ÑÐ½Ð¾ÑÑÐ¸ Ð²ÑÑÐºÐ°Ð·ÑÐ²Ð°Ð½Ð¸Ð¹ Ð² ÑÐ¾ÑÐ¸Ð°Ð»ÑÐ½Ð¾Ð¹ ÑÐµÑÐ¸. ÐÐ°ÐºÐ»ÑÑÐµÐ½Ð¸Ðµ Ð²ÐºÐ»ÑÑÐ°ÐµÑ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð²ÑÐ²Ð¾Ð´Ñ Ð¿Ð¾ ÑÐ°Ð±Ð¾ÑÐµ.
description: The aim of this thesis is to investigate data analysis and data mining methods presented in MS SQL Server and R. This thesis first examines various mining methods used in data analysis in different situations. The following problem types were considered: clustering, association rules, classification, time series and visualization. In a second stage the work with relational database was performed. The relevant methods were applied to the specific problem in order to build mining models with MS SQL Server and R for clustering, classification and prediction purposes. Finally, the specific R tools for the analysis of poorly structured data were used and the Twitter posts sentiment analysis was performed.
Quantification and localization of matrix metalloproteinases (MMP15 and MMP19) in human colorectal carcinogenesis
Creators: name: Sena, Paola
name: Mariani, Francesco
name: Marzona, Laura
name: Roncucci, Luca
name: Palumbo, Carla
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: matrix metalloproteinases (MMPs); colorectal carcinogenesis; quantitative reverse transcription polymerase chain reaction (qRT-PCR)

description: Matrix metalloproteinases (MMPs) are capable of degrading all kinds of extracellular matrix proteins, but they also can process a number of other bioactive molecules. They are well known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands (as FAS ligand) and chemokine/cytokine activation/de-activation. MMPs are also thought to play a pivotal role on cell processes like proliferation, migration (adhesion/dispersion), differentiation, apoptosis and host defence; thus they have been extensively studied to elucidate their involvement in both tumour development and progression. In the present study the attention was focused on two members of MMP family, i.e. MMP-15 and MMP-19, not jet well investigated as far as their role is concerned in the onset of colorectal neoplastic pathologies. The expression profile of MMP-15 and MMP-19 was assayed from samples of: a) normal mucosa, b) microadenomas and c) cancer, using confocal analysis, Western blotting and quantitative reverse transcription polymerase chain reaction (qRT-PCR). Western blot and qRT-PCR showed that MMP-15 expression level increases from normal mucosa to microadenomas, with a reduced level in cancer respect to microadenomas. The semiquantitative immunofluorescence analysis correlate with these data showing a localization exclusively at the stromal level of this protein, suggestive of an important role of stromal compartment, especially in the early phases of neoplastic transformation. Increasingly amount of MMP-19 mRNA and protein levels were instead recorded in the progression of colon lesions both in epithelial and stromal compartments. MMP-19 staining increases in parallel to normal mucosa ® microadenoma® carcinoma sequence; in particular this protein was showed to be expressed at the epithelial level only at the end of the sequence, indicating an intriguing epithelial involvement of MMP-19 production only in the late stages of carcinogenesis. In conclusion, MMP-15 and MMP-19 appear to be up-regulated during tumorogenesis, with different expression patterns, which in turn are probably due to the different roles played by these two molecules. The results reported up to now in literature show conflicting data regarding the specific role of these proteins in tumour progression so that the improved understanding of the biological roles of MMPs in colorectal cancer suggests a re-evaluation of the use of MMP inhibitors and highlights the importance of integrated translational studies on the MMP expression patterns.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
Rosuvastatin-induced changes in mice kidney were remodeled by dietary essential amino acids supplementation
Creators: name: Corsetti, G.
name: Romano, C.
name: D'Antona, G.
name: Nisoli, E.
name: Dioguardi, F.S.
name: Stacchiotti, A.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: Rosuvastatin; kidney; stress proteins; essential amino acids; mice

description: Rosuvastatin (Rvs) represents one of the most used cholesterol-lowering statins even if its effects may be wider than simply regulation of lipids metabolism [1]. Despite the efficacy in preventing cardiovascular diseases, long-term delivery of statins is associated to adverse effects [2]. So here we studied healthy normotensive mice fed with Rvs at a therapeutic dose (20 mg/kg/day) for one month. To evaluate the influence of dietary essential amino acids mixture (EAAm) in this model, other mice were fed with Rvs and EAAm daily for one month. A normal rodent chow or EAAm supplementation for the same period were further administered in control groups. Ultrastructural analysis of the glomerular filtration barrier did not show any difference between groups. Glomerular area together with mitochondria and lysosomal parameters in renal tubules were evaluated. Moreover we focused on the distribution of chaperones and mitochondria markers (Grp75, Grp78, Bcl2), nitric oxide isoforms (iNOS and eNOS), and cell adhesion molecules (E-cadherin and β-catenin). Control groups were similar except for increased mitochondria density and Grp75 staining after EAAm diet. In contrast, Rvs attenuated Grp75/Bcl2 patterns, but enhanced Grp78 expression. Remarkably E-cadherin shifted from the basolateral to the apical side in proximal tubules while evident β-catenin signal was maintained mainly in the distal tubules and in the macula densa. However, after one month of EAAm supplementation, all parameters become almost similar to controls, except for Bcl2 that persisted at higher level. These novel data suggest that, under basal conditions, Rvs may regulate proximal tubular polarity, lysosomes and mitochondria distribution. EAAm supplementation further reinforces the tubular structure in the kidney, stimulating mitochondriogenesis, as corroborated by morphometry, intense Bcl2 and vascular eNOS expressions. However to validate the efficacy of dietary of EAAm combined with Rvs therapy further studies on the renal function are mandatory.
description: Italian Journal of Anatomy and Embryology, Vol 117, No 2 (Supplement) 2012
Cyclists' Consideration of Energy Expenditure and Air Pollution in Route Planning : Planning and Policy Implications
Creators: name: Hammer, Evan J.
Publisher: name: The University of British Columbia
Year: 2018

description: Despite the many positive benefits of cycling, and negative health risks of air pollution, very little is known about cyclists’ consideration of air pollution when route planning. Even less is known about the role of energy expenditure in route planning. An intercept survey of cyclists was conducted in the city of Vancouver in the summer of 2016. A total of 648 participants took part in the study. After data cleaning, there were 602 respondents remaining in the sample. Two ordinal logistic regression models were developed, one for cyclists’ consideration of air pollution and the second for their consideration of energy expenditure in route planning. The model with consideration of air pollution as the dependent variable had five independent variables. Cyclists who consider energy expenditure, walk frequently, cycle year-round, enjoy physical activity and who are older are more likely to consider air pollution when choosing a route. The second model had consideration of energy expenditure as the dependent variable and four independent variables. Respondents who see bicycling as exercise, are comfortable on major streets, and enjoy physical activity are more likely to consider energy expenditure when route planning. Those with higher income levels were somewhat less likely to consider energy expenditure. The types of cyclists who are more likely to consider air pollution and energy expenditure when choosing a route can be roughly placed in two categories – ‘health conscious’ and ‘committed’ cyclists. There are a number of potential implications of these findings. Future research should build on these findings and include energy expenditure and air pollution consideration in route planning studies. Public education can improve the public’s awareness of air pollution, especially for those less likely to consider pollution in route planning, and provide better information on limiting pollution exposure when route planning. Planners can provide a variety of cycling infrastructure to accommodate a range of cycling types, and design bike routes in ways that limit pollution exposure.
title: ÐÐ½Ð°Ð»Ð¸Ð· Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ ÑÐµÐ½Ð¾ÑÐ¸Ð¿Ð° ÐºÐ»ÐµÑÐ¾Ðº HaCaT Ð¸ A431 Ð¿ÑÐ¸ Ð¿Ð¾Ð¼Ð¾ÑÐ¸ CellProfiler
title: Phenotype change analysis of HaCaT and A431 cells using CellProfiler software
Creators: name: ÐÐ°ÑÐ°ÑÐ¾Ð², Ð.
name: ÐÐµÑÐµÐ»Ð¾Ð²Ð°, Ð.
name: Ð¡Ð°Ð¸Ð´Ð¾Ð²Ð°, Ð.
name: Ð¡Ð°Ð²Ð¸ÑÐºÐ°Ñ, Ð.
name: ÐÐ½Ð¸ÑÐµÐ½ÐºÐ¾, Ð.
name: "ÐÐ¾Ð»Ð»ÐµÐºÑÐ¸Ð¸ ÐºÑÐ»ÑÑÑÑ ÐºÐ»ÐµÑÐ¾Ðº ÑÐµÐ»Ð¾Ð²ÐµÐºÐ° Ð¸ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÑ : ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÐµ Ð²ÑÐ·Ð¾Ð²Ñ Ð¸ ÑÐµÑÐµÐ²ÑÐµ ÑÐµÑÐµÐ½Ð¸Ñ", Ð²ÑÐµÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ°Ñ ÑÐºÐ¾Ð»Ð°-ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ñ (2022; Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³)
Publisher: name: ÐÐÐÐÐ¢ÐÐ¥-ÐÐ ÐÐ¡Ð¡
Year: 2022
Subjects: ÐÐ»ÐµÑÐºÐ° (Ð±Ð¸Ð¾Ð».)

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐ¾Ð´ÐµÐ¼Ð¾Ð½ÑÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð° Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ° Ð°Ð½Ð°Ð»Ð¸Ð·Ð° ÑÐµÐ½Ð¾ÑÐ¸Ð¿Ð° ÐºÐ»ÐµÑÐ¾Ðº Ð² Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ðµ CellProfiler Ñ Ð¿Ð¾ÑÐ»ÐµÐ´ÑÑÑÐµÐ¹ Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ¾Ð¹ Ð² RStudio.
title: ÐÐµÑÐ¾Ð´Ð¸ÐºÐ° Ð¾ÑÐµÐ½ÐºÐ¸ Ð½Ð°Ð´ÐµÐ¶Ð½Ð¾ÑÑÐ¸ Ð²Ð½ÐµÑÐ½ÐµÑÐ¾ÑÐ³Ð¾Ð²Ð¾Ð³Ð¾ Ð¿Ð°ÑÑÐ½ÐµÑÐ°
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð¯ÐºÐ¾Ð²Ð»ÐµÐ²Ð°, ÐÐ»ÑÐ³Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð²Ð½ÐµÑÐ½ÑÑ ÑÐ¾ÑÐ³Ð¾Ð²Ð»Ñ
Ð²Ð½ÐµÑÐ½ÐµÑÐ¾ÑÐ³Ð¾Ð²ÑÐµ Ð¾ÑÐ½Ð¾ÑÐµÐ½Ð¸Ñ
Ð²Ð½ÐµÑÐ½ÐµÑÐ¾ÑÐ³Ð¾Ð²ÑÐµ Ð¿Ð°ÑÑÐ½ÐµÑÑ
Ð²Ð½ÐµÑÐ½ÐµÑÐ¾ÑÐ³Ð¾Ð²Ð°Ñ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÑ

description: ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð²Ð½ÐµÑÐ½ÐµÑÐ¾ÑÐ³Ð¾Ð²Ð¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐÐÐ Â«ÐÐ°Ð·Ð°Ð½ÑÐºÐ¸Ð¹ Ð²ÐµÑÑÐ¾Ð»ÑÑÐ½ÑÐ¹ Ð·Ð°Ð²Ð¾Ð´Â». ÐÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð° ÑÐ¸ÑÑÐµÐ¼Ð° Ð¾ÑÐµÐ½ÐºÐ¸ Ð±Ð»Ð°Ð³Ð¾Ð½Ð°Ð´ÐµÐ¶Ð½Ð¾ÑÑÐ¸ Ð²Ð½ÐµÑÐ½ÐµÑÐ¾ÑÐ³Ð¾Ð²ÑÑ Ð¿Ð°ÑÑÐ½ÐµÑÐ¾Ð² Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ Â«ÐÐ°Ð·Ð°Ð½ÑÐºÐ¸Ð¹ Ð²ÐµÑÑÐ¾Ð»ÑÑÐ½ÑÐ¹ Ð·Ð°Ð²Ð¾Ð´Â». ÐÑÑÐ²Ð»ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð½ÐµÐ´Ð¾ÑÑÐ°ÑÐºÐ¸, Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ¸, Ð¿ÑÐ¸Ð¼ÐµÐ½ÑÐµÐ¼Ð¾Ð¹ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸ÐµÐ¼ Ð´Ð»Ñ Ð¾ÑÐµÐ½ÐºÐ¸ Ð²Ð½ÐµÑÐ½ÐµÑÐ¾ÑÐ³Ð¾Ð²ÑÑ Ð¿Ð°ÑÑÐ½ÐµÑÐ¾Ð² Ð² Ð½Ð°ÑÑÐ¾ÑÑÐµÐµ Ð²ÑÐµÐ¼Ñ. ÐÑÐ»Ð¸ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ² Ð¾ÑÐµÐ½ÐºÐ¸ Ð¿Ð°ÑÑÐ½ÐµÑÐ¾Ð² ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸. ÐÐ° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð²Ð½ÐµÑÐ½ÐµÑÐ¾ÑÐ³Ð¾Ð²ÑÑ Ð¿Ð°ÑÑÐ½ÐµÑÐ¾Ð² Ð±ÑÐ»Ð¸ ÑÐ´ÐµÐ»Ð°Ð½Ñ Ð²ÑÐ²Ð¾Ð´Ñ Ð¾ Ð½Ð°Ð´ÐµÐ¶Ð½Ð¾ÑÑÐ¸ Ð¿Ð°ÑÑÐ½ÐµÑÐ¾Ð² ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸ ÐÐÐ Â«ÐÐ°Ð·Ð°Ð½ÑÐºÐ¸Ð¹ Ð²ÐµÑÑÐ¾Ð»ÑÑÐ½ÑÐ¹ Ð·Ð°Ð²Ð¾Ð´Â».
Lorentz violation with an antisymmetric tensor
Creators: name: Altschul, Brett
name: Bailey, Quentin G.
name: Kostelecky, Alan
Publisher: name: arXiv
Year: 2009
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Field theories with spontaneous Lorentz violation involving an antisymmetric 2-tensor are studied. A general action including nonminimal gravitational couplings is constructed, and features of the Nambu-Goldstone and massive modes are discussed. Minimal models in Minkowski spacetime exhibit dualities with Lorentz-violating vector and scalar theories. The post-newtonian expansion for nonminimal models in Riemann spacetime involves qualitatively new features, including the absence of an isotropic limit. Certain interactions producing stable Lorentz-violating theories in Minkowski spacetime solve the renormalization-group equations in the tadpole approximation.
description: 18 pages two-column REVTeX
Dopaminergic system is differently altered in hippocampus and facial nucleus of trimethyltin rat model
Creators: name: Pompili, Elena
name: Mignini, Fiorenzo
name: Nasuti, Cinzia
name: Artico, Marco
name: Giovannetti, Filippo
name: Fabrizi, Cinzia
name: Iannetti, Giorgio
name: Fumagalli, Lorenzo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: Dopamine receptors and transporters; trimethyltin; hippocampus; facial nucleus

description: Trimethyltin (TMT) is an organotin compound which is considered a useful tool to obtain an animal model of neurodegeneration associated with cognitive impairment (Pompili et al., 2011; Geloso et al., 2011). In the present work, this model was used in order to investigate the animal behaviour in association with the immunohistochemical expression of dopaminergic system (D1- and D2-like receptors and dopamine transporters DAT, VMAT-1 and -2) and cells viability (NEU-N) in the rat hippocampus and facial nucleus regions. TMT-treated group showed impaired spatial reference memory in a Morris water maze task compared to control group whereas the memory consolidation tested 24h after was preserved. In the open field, TMT-treated rats showed a decreased in time spent in rearing episodes reflecting a lower interest to explore a novel environment. In the hippocampal area of TMT-treated group, cell viability was significantly reduced by 45.9% whereas the D1, D2, DAT and VMAT- 2 receptor proteins immunoreactivity was significantly decreased by 57.5, 72.8, 64.1, 72.1%. In the facial nucleus, immunoreactivity reduction was observed only for dopamine transporters (average: 60% about) while the NEU-N reduction was 40%. These data were confirmed by real time RT-PCR analysis. These results suggest a differential involvement of the D1-type and D2-type receptors in the regulation of learning and memory. Besides, alterations on the functional ratio of DAT to VMAT-2 could predispose the cells to injury even at very low doses of TMT. The data obtained in facial nucleus demonstrate a different sensibility to xenobiotic of dopamine receptors and transporters. The TMT model could contribute to elucidate the role of dopaminergic system on two different CNS regions. Supported by PRIN 2008 - prot. 20089MANHH_002 and prot. 20089MANHH_003.
description: Italian Journal of Anatomy and Embryology, Vol 117, No 2 (Supplement) 2012
title: ÐÐ°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¸ ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¿ÑÐ¾ÑÐµÑÑÐ¾Ð² Ð¿Ð¾Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ñ Ð²Ð·ÑÑÐ²Ð½ÑÑ ÑÐ´Ð°ÑÐ½ÑÑ Ð²Ð¾Ð»Ð½
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: ÐÐ°Ð¿ÑÐ°Ð»Ð¾Ð²Ð°, ÐÐ½Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÐÐ¾Ð»Ð½Ñ ÑÐ´Ð°ÑÐ½ÑÐµ
ÐÐ·ÑÑÐ²
Ð¸Ð·Ð±ÑÑÐ¾ÑÐ½Ð¾Ðµ Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ðµ
Ð²Ð·ÑÑÐ²Ð¾Ð·Ð°ÑÐ¸ÑÐ½ÑÐµ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð°
Ð²Ð·ÑÑÐ²Ð¾Ð·Ð°ÑÐ¸ÑÐ½ÑÐµ ÑÐ¾Ð¾ÑÑÐ¶ÐµÐ½Ð¸Ñ

description: Ð Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ¾Ð¹ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ð¸ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð¾Ð±Ð·Ð¾Ñ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÑ Ð¸ Ð¿ÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ð½ÑÑ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ð¿Ð¾Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿Ð¾ÑÐ°Ð¶Ð°ÑÑÐµÐ³Ð¾ Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ Ð²Ð·ÑÑÐ²Ð½ÑÑ ÑÐ´Ð°ÑÐ½ÑÑ Ð²Ð¾Ð»Ð½, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ñ ÑÑÐµÐ´ÑÑÐ², ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð½ÑÑ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÑÐ¸Ñ Ð¼ÐµÑÐ¾Ð´Ð¾Ð². ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¾ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¸ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ°Ð»ÑÐ½Ð¾Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ ÐºÐ¾Ð¼Ð±Ð¸Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ Ð²Ð·ÑÑÐ²Ð¾Ð·Ð°ÑÐ¸ÑÐ½ÑÑ ÑÑÑÑÐ¾Ð¹ÑÑÐ², ÑÐ¾ÑÐµÑÐ°ÑÑÐ¸Ñ Ð²ÑÑÐ¾ÐºÐ¸Ðµ Ð¿ÑÐ¾ÑÐ½Ð¾ÑÑÐ½ÑÐµ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ¸ Ñ ÑÐµÐ»Ð°ÐºÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÐ¼ Ð²Ð¾Ð·Ð´ÐµÐ¹ÑÑÐ²Ð¸ÐµÐ¼ Ð½Ð° Ð²Ð·ÑÑÐ²Ð½ÑÐµ ÑÐ´Ð°ÑÐ½ÑÐµ Ð²Ð¾Ð»Ð½Ñ Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½ÑÑ Ð¼Ð½Ð¾Ð³Ð¾ÑÐ°Ð·Ð½ÑÑ ÑÑÐµÐ´.
Geometric and Topological Inference for Deep Representations of Complex Networks
Creators: name: Lin, Baihan
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Geometric Topology (math.GT)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: FOS: Biological sciences

description: Understanding the deep representations of complex networks is an important step of building interpretable and trustworthy machine learning applications in the age of internet. Global surrogate models that approximate the predictions of a black box model (e.g. an artificial or biological neural net) are usually used to provide valuable theoretical insights for the model interpretability. In order to evaluate how well a surrogate model can account for the representation in another model, we need to develop inference methods for model comparison. Previous studies have compared models and brains in terms of their representational geometries (characterized by the matrix of distances between representations of the input patterns in a model layer or cortical area). In this study, we propose to explore these summary statistical descriptions of representations in models and brains as part of a broader class of statistics that emphasize the topology as well as the geometry of representations. The topological summary statistics build on topological data analysis (TDA) and other graph-based methods. We evaluate these statistics in terms of the sensitivity and specificity that they afford when used for model selection, with the goal to relate different neural network models to each other and to make inferences about the computational mechanism that might best account for a black box representation. These new methods enable brain and computer scientists to visualize the dynamic representational transformations learned by brains and models, and to perform model-comparative statistical inference.
description: To appear in Proceeding of WWW 2022. This work extends our prior work (arXiv:1810.02923, arXiv:1906.09264, arXiv:1902.10658) and put them in perspectives along with many other ongoing research in this direction
title: ÐÐ°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÐºÐ°ÑÑÐµÑÐ½ÑÑ ÑÐºÑÐºÐ°Ð²Ð°ÑÐ¾ÑÐ¾Ð² Ð² ÑÑÐµÐ½Ð°Ð¶ÐµÑÐ¾ÑÑÑÐ¾ÐµÐ½Ð¸Ð¸
title: Ð°Ð²ÑÐ¾ÑÐµÑ. Ð´Ð¸Ñ. â¦ ÐºÐ°Ð½Ð´. ÑÐµÑ Ð½. Ð½Ð°ÑÐº: 05.13.18
titleType: Subtitle
Creators: name: ÐÐ¾ÑÑÑÐ³Ð¾Ð²Ð°, ÐÐ°ÑÑÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÐÐ°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
Ð¢ÑÐµÐ½Ð°Ð¶ÐµÑÑ
ÐÐ°ÑÑÐµÑÐ½ÑÐ¹ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑ
Ð­ÐºÑÐºÐ°Ð²Ð°ÑÐ¾ÑÑ

description: ÐÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð° Ð´ÐµÐºÐ¾Ð¼Ð¿Ð¾Ð·Ð¸ÑÐ¸Ñ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð¼Ð¾Ð´ÐµÐ»Ð¸ ÐºÐ°ÑÑÐµÑÐ½Ð¾Ð³Ð¾ ÑÐºÑÐºÐ°Ð²Ð°ÑÐ¾ÑÐ°, Ð¾Ð±ÐµÑÐ¿ÐµÑÐ¸Ð²ÑÐ°Ñ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÑ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ¸ ÑÐ¸Ð»Ð¾Ð²ÑÑ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¹, ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ñ, Ð¿Ð½ÐµÐ²Ð¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¸ ÑÐµÐ¿Ð»Ð¾Ð²ÑÑ Ð¿Ð¾Ð´ÑÐ¸ÑÑÐµÐ¼ Ð¼Ð°ÑÐ¸Ð½Ñ Ð¿ÑÐ¸ ÐµÐµ Ð²Ð·Ð°Ð¸Ð¼Ð¾Ð´ÐµÐ¹ÑÑÐ²Ð¸Ð¸ Ñ Ð¾ÐºÑÑÐ¶Ð°ÑÑÐµÐ¹ ÑÑÐµÐ´Ð¾Ð¹. Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½ Ð³ÑÐ°ÑÐ¾Ð²ÑÐ¹ Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼ ÑÐµÑÐµÐ½Ð¸Ñ Ð»Ð¸Ð½ÐµÐ¹Ð½ÑÑ Ð¸ Ð½ÐµÐ»Ð¸Ð½ÐµÐ¹Ð½ÑÑ ÑÐ¸ÑÑÐµÐ¼ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ð¹. ÐÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½ÑÐ¹ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑ, ÑÐµÐ°Ð»Ð¸Ð·ÑÑÑÐ¸Ð¹ ÑÐ¸ÑÐ»ÐµÐ½Ð½ÑÐµ Ð¼ÐµÑÐ¾Ð´Ñ ÑÐµÑÐµÐ½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ð¹ Ð² ÑÐµÐ¶Ð¸Ð¼Ðµ ÑÐµÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð²ÑÐµÐ¼ÐµÐ½Ð¸ Ñ ÑÐ¾ÑÐ½Ð¾ÑÑÑÑ, Ð´Ð¾ÑÑÐ°ÑÐ¾ÑÐ½Ð¾Ð¹ Ð´Ð»Ñ Ð²Ð¾ÑÐ¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ð¸Ñ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð² ÑÐºÑÐºÐ°Ð²Ð°ÑÐ¾ÑÐ° Ð² ÑÐ¸ÑÐ¾ÐºÐ¾Ð¼ Ð´Ð¸Ð°Ð¿Ð°Ð·Ð¾Ð½Ðµ ÑÐºÑÐ¿Ð»ÑÐ°ÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÑ Ð¸ Ð°Ð²Ð°ÑÐ¸Ð¹Ð½ÑÑ ÑÐµÐ¶Ð¸Ð¼Ð¾Ð² ÑÐ°Ð±Ð¾ÑÑ Ð´Ð»Ñ Ð·Ð°Ð´Ð°Ñ ÑÑÐµÐ½Ð°Ð¶ÐµÑÐ½Ð¾Ð¹ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Ð¾Ð¿ÐµÑÐ°ÑÐ¾ÑÐ¾Ð².
P.Oxy. XLIV 3152. Euripides, Hippolytus 225-59, 269-87, 357-67, 371-94, 442-55
Creators: name: Oxyrhynchus Papyri
Publisher: name: University of Oxford
Year: 2022
Subjects: Latin and classical Greek languages

description: Reproduction requests: https://www.ees.ac.uk/reproduction-requests-and-fees
Vitamin E modifies poly(D,L)lactic acid wettability and reduces bacterial adhesion
Creators: name: Rizzi, Manuela
name: Pittarella, Pamela
name: Campoccia, Davide
name: Cangini, Ilaria
name: Montanaro, Lucio
name: Arciola, Carla Renata
name: Manzoli, Francesco Antonio
name: Renò, Filippo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: Polylactic acid; Vitamin E; wettability; bacterial adhesion

description: Highly biocompatible polylactic acid (PLA)-derived polymers are used for different biomedical applications such as orthopaedic screws and drug delivery devices. Nevertheless their clinical use is limited by their proinflammatory characteristics. Vitamin E (α-tocopherol, Vit. E), a natural antioxidant and anti-inflammatory agent has been used to improve different biomaterials biostability [1], and among them also P(D,L)LA [2]. In this work, addition of Vit.E (10-40% w/v) to P(D,L)LA films obtained by solvent casting technique increased polymer surface wettability and human plasma protein adsorption, while addition of Vit.E acetate (Vit.E Ac, 10-40% w/v), the acetic ester of α-tocopherol, often used as an alternative to Vit.E itself, failed in modifying polymer wettability. On the other hand, bacterial adhesion experiments onto control, Vit.E and Vit.E Ac enriched P(D,L)LA films showed that both presence of Vit.E and Vit.E Ac was able to reduce the adhesion of the RP62A Staphylococcus epidermidis strain [3]. In particular, in PLA + Vit. E samples the decrease in bacterial adhesion was of 56%, while, in the case of PLA + Vit. E Ac samples the decrease was of 40%. These preliminary data suggest that Vit. E addition to PLA containing medical devices could improve their resistance to bacterial infections.
description: Italian Journal of Anatomy and Embryology, Vol 117, No 2 (Supplement) 2012
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÑÐ´Ð¾Ð²Ð¾Ð¹ Ð¿Ð¾Ð¶Ð°ÑÐ½Ð¾Ð¹ ÑÐ¸Ð³Ð½Ð°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð¡ÐºÐ°Ð»ÑÑÐºÐ¸Ð¹, ÐÐ»Ð°Ð´Ð¸ÑÐ»Ð°Ð²
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð¿Ð¾Ð¶Ð°ÑÐ½Ð°Ñ ÑÐ¸Ð³Ð½Ð°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ
Ð¸Ð·Ð²ÐµÑÐ°ÑÐµÐ»Ñ
Ð²Ð¾Ð·Ð³Ð¾ÑÐ°Ð½Ð¸Ðµ
Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð°Ñ ÑÐ¸ÑÑÐµÐ¼Ð°

description: ÐÐ·Ð»Ð¾Ð¶ÐµÐ½ Ð¿Ð¾Ð´ÑÐ¾Ð´ Ðº ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð°Ð´ÑÐµÑÐ½Ð¾-Ð°Ð½Ð°Ð»Ð¾Ð³Ð¾Ð²Ð¾Ð¹ ÑÑÐ´Ð¾Ð²Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Ð¿Ð¾Ð¶Ð°ÑÐ½Ð¾Ð¹ ÑÐ¸Ð³Ð½Ð°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÑÐ´Ð¾Ð²ÑÑ ÑÐ¸ÑÑÐµÐ¼ Ð¿Ð¾Ð¶Ð°ÑÐ¾ÑÑÑÐµÐ½Ð¸Ñ, Ð¾ÑÑÑÐµÑÑÐ²Ð»ÐµÐ½ Ð²ÑÐ±Ð¾Ñ Ð´Ð°ÑÑÐ¸ÐºÐ¾Ð² Ð¸ Ð¿ÑÐ¸ÐµÐ¼Ð½Ð¾-ÐºÐ¾Ð½ÑÑÐ¾Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ. ÐÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð° Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ°Ñ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐ¸ÑÑÐµÐ¼Ñ Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ Ð¿ÑÐ¾ÐµÐºÑÐ° Ð¼Ð°Ð»Ð¾Ð³Ð¾ Ð³Ð¸Ð´ÑÐ¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÑÐ´Ð½Ð°.
In the diffraction shadow: Norton waves versus surface plasmon-polaritons in the optical region
Creators: name: Nikitin, A. Yu.
name: Rodrigo, Sergio G.
name: Garcia-Vidal, F. J.
name: Martin-Moreno, L.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: Surface electromagnetic modes supported by metal surfaces have a great potential for uses in miniaturised detectors and optical circuits. For many applications these modes are excited locally. In the optical regime, Surface Plasmon Polaritons (SPPs) have been thought to dominate the fields at the surface, beyond a transition region comprising 3-4 wavelengths from the source. In this work we demonstrate that at sufficiently long distances SPPs are not the main contribution to the field. Instead, for all metals, a different type of wave prevails, which we term Norton waves for their reminiscence to those found in the radio-wave regime at the surface of the Earth. Our results show that Norton Waves are stronger at the surface than SPPs at distances larger than 6-9 SPP's absorption lengths, the precise value depending on wavelength and metal. Moreover, Norton waves decay more slowly than SPPs in the direction normal to the surface.
description: 8 pages, 8 figures
The Innovation Economy and the Housing Crisis : Examining the Decoupling of Vancouver’s Housing and Labour Markets and the Impact on the Social Landscape
Creators: name: Mao, Frankie
Publisher: name: The University of British Columbia
Year: 2018

description: As Vancouver navigates economic development in its current-day economic climate, there is pressure to further define the city’s global identity as a progressive international hub through supporting and fostering tech and cultural industries - or as coined by the city: Innovation Economies. These innovative industries are creative, non-traditional, and entrepreneurial departures from the transnational finance, service, and resource-based sectors that dominate the city’s economy. A handful of districts and neighbourhoods have been identified in and around the Downtown Core as districts to develop and foster Innovation, with the bulk of the labour force primarily made up of young, entry-level professionals in the creative industries. In a residential real estate sector characterized by high costs, competitive and increasingly unavailable rental stock, external investment factors, and contested vacancy rates, ‘innovators’ are in the very thick of Vancouver’s housing crisis, experiencing firsthand the decoupling effects of the housing and labour markets, and raising concerns about Vancouver’s uncertain future. In a post-industrial narrative dominated by its transnational housing market, Vancouver is rapidly outgrowing its capacity to absorb and control the externalities inherent in the neoliberal development model. The revival of the new economy provides promise and possibility amidst increasingly emergent issues of social disparity. New concerns arise in both the long and short term economic sustainability of innovation, the affordability of living, and the retention of the skilled workforce needed to sustain the new economy. Drawing on existing literature and theory on creative cities and cultural economies, and placing them within the context of Vancouver's unique social and economic landscape, this qualitative analytical paper examines the complexities and intersectionalities of Innovative Economies, residential development, and the delicate social spaces situated in between.
Escape of stars from gravitational clusters in the Chandrasekhar model
Creators: name: Lemou, Mohammed
name: Chavanis, Pierre-Henri
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the evaporation of stars from globular clusters using the simplified Chandrasekhar model. This is an analytically tractable model giving reasonable agreement with more sophisticated models that require complicated numerical integrations. In the Chandrasekhar model: (i) the stellar system is assumed to be infinite and homogeneous (ii) the evolution of the velocity distribution of stars f(v,t) is governed by a Fokker-Planck equation, the so-called Kramers-Chandrasekhar equation (iii) the velocities |v| that are above a threshold value R>0 (escape velocity) are not counted in the statistical distribution of the system. In fact, high velocity stars leave the system, due to free evaporation or to the attraction of a neighboring galaxy (tidal effects). Accordingly, the total mass and energy of the system decrease in time. If the star dynamics is described by the Kramers-Chandrasekhar equation, the mass decreases to zero exponentially rapidly. Our goal is to obtain non-perturbative analytical results that complement the seminal studies of Chandrasekhar, Michie and King valid for large times $t\to+\infty$ and large escape velocities $R\to +\infty$. In particular, we obtain an exact semi-explicit solution of the Kramers-Chandrasekhar equation with the absorbing boundary condition f(R,t)=0. We use it to obtain an explicit expression of the mass loss at any time t when $R\to +\infty$. We also derive an exact integral equation giving the exponential evaporation rate $λ(R)$, and the corresponding eigenfunction $f_λ(v)$, when $t\to +\infty$ for any sufficiently large value of the escape velocity R. For $R\to +\infty$, we obtain an explicit expression of the evaporation rate that refines the Chandrasekhar results.
Examining the contribution of basic numerical and non-numerical skills to growth in mathematical learning.
Creators: name: Weiers, Hanna
name: Xenidou-Dervou, Iro
name: Sohnia Ghattaura
name: Wortha, Franz
name: Sella, Francesco
name: Simms, Victoria
name: Scerif, Gaia
name: Gilmore, Camilla
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Education
subject: Child Psychology
subject: Cognitive Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Early Childhood Education

description: This is the first pre-registration for the longitudinal study associated with Challenge 1 of the CEML.
The full pre-registration can be found in the attached file.
“Sulla Questione Universitaria”: Filippo Pacini and medical-anatomical education in the Nineteenth century
Creators: name: Zurlini, Fabiola
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: Filippo Pacini; medical education

description: The paper focuses on Filippo Pacini ‘s remarks and considerations about the reform of medical and surgical university schools in Italy in the Nineteenth century that he illustrated in his brief work “Sulla Questione Universitaria” . He published It in 1878, while he was full professor at the medical and surgical school at the University of Florence. Pacini outlines the state and the development of the medical and anatomical studies in Italy in relationship with the European context, describing his personal experience as medical student, university lecturer and researcher. All his considerations involves political and scientific institutions through a brilliant, lively and modern dialogue. Pacini’s considerations about medical and anatomical schools are still relevant today, to understand the value and the meaning of medical schools for the development of the science and of a nation.
description: Italian Journal of Anatomy and Embryology, Vol 117, No 2 (Supplement) 2012
title: Ð¢Ð¾Ð²Ð°ÑÐ¾Ð²ÐµÐ´Ð½Ð°Ñ Ñ Ð°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ° Ð¸ ÑÑÐ°Ð²Ð½Ð¸ÑÐµÐ»ÑÐ½Ð°Ñ ÑÐ¾Ð²Ð°ÑÐ¾Ð²ÐµÐ´Ð½Ð°Ñ Ð¾ÑÐµÐ½ÐºÐ° ÐºÐ°ÑÐµÑÑÐ²Ð° Ð½Ð°ÑÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÐºÐ¾ÑÐµ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°Ð½Ð´Ð°ÑÐ¾Ð²Ð°, ÐÐ¾Ð»Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð½Ð°ÑÑÑÐ°Ð»ÑÐ½ÑÐ¹ ÐºÐ¾ÑÐµ
Ð¶Ð°ÑÐµÐ½ÑÐ¹ ÐºÐ¾ÑÐµ
ÑÐ¾Ð²Ð°ÑÐ¾Ð²ÐµÐ´Ð½Ð°Ñ Ñ Ð°ÑÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ°
ÐºÐ¾ÑÐµ

description: Ð¦ÐµÐ»ÑÑ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ ÑÐ¾Ð²Ð°ÑÐ¾Ð²ÐµÐ´Ð½Ð°Ñ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ° Ð¸ ÑÑÐ°Ð²Ð½Ð¸ÑÐµÐ»ÑÐ½Ð°Ñ ÑÐ¾Ð²Ð°ÑÐ¾Ð²ÐµÐ´Ð½Ð°Ñ Ð¾ÑÐµÐ½ÐºÐ° ÐºÐ°ÑÐµÑÑÐ²Ð° Ð½Ð°ÑÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÐºÐ¾ÑÐµ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´Ð¸ÑÐµÐ»ÐµÐ¹, ÑÐµÐ°Ð»Ð¸Ð·ÑÐµÐ¼ÑÑ Ð² ÑÐ¾Ð·Ð½Ð¸ÑÐ½Ð¾Ð¹ ÑÐ¾ÑÐ³Ð¾Ð²Ð¾Ð¹ ÑÐµÑÐ¸ Ð³. Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³Ð°. Ð ÑÐ°Ð±Ð¾ÑÐµ Ð±ÑÐ»Ð¸ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²Ð° Ð¶Ð°ÑÐµÐ½Ð½Ð¾Ð³Ð¾ ÐºÐ¾ÑÐµ, Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸, ÑÐ¾ÑÐ¼Ð¸ÑÑÑÑÐ¸Ðµ ÐºÐ°ÑÐµÑÑÐ²Ð¾; Ð´Ð°Ð½Ð° ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ° Ð¼ÐµÑÐ¾Ð´Ð¾Ð², Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÐºÐ¾ÑÐ¾ÑÑÑ Ð±ÑÐ»Ð¸ Ð¾ÑÑÑÐµÑÑÐ²Ð»ÐµÐ½Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ; Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ð° ÑÑÐ°Ð²Ð½Ð¸ÑÐµÐ»ÑÐ½Ð°Ñ ÑÐºÑÐ¿ÐµÑÑÐ¸Ð·Ð° ÐºÐ°ÑÐµÑÑÐ²Ð° Ð¶Ð°ÑÐµÐ½Ð½Ð¾Ð³Ð¾ ÐºÐ¾ÑÐµ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð¼Ð°ÑÐ¾Ðº.
Evaluation of driving posture for a competition wheelchair based on the relationship between physical load and manipulation force
Creators: name: Tsuchiya, Yugo
name: Kinoshita, Yukiya
name: Kiriyama, Yoshimori
name: Tanaka, Katsumasa
Publisher: name: Loughborough University
Year: 2024

description: Engineering of Sport 15 - Proceedings from the 15th International Conference on the Engineering of Sport (ISEA 2024)
Competition wheelchairs are required to have various functions, such as quick turning, sudden starting and braking, and high speed driving. One of the previous studies on injuries in wheelchair athletes showed that the relationship between muscle weakness and shoulder pain was due to atrophy of the muscles around the scapula. If it would be possible to evaluate wheelchairs in view of the physical load, a suitable wheelchair may be individually selected for the athlete, and may lead to the reduction of injury risk. A method using the functional evaluation of effective muscle strength has been proposed as an example of evaluation for sports equipment and human exercise focusing on muscle characteristics. It was claimed that the method can evaluate output force of a limb and the mechanical properties of the muscles based on the functional role of the muscles. In this study, the method was applied to the wheelchair operation to calculate an effective muscle manipulative force (EMMF) using the muscle force estimated from the inverse dynamics analysis. This study also investigated the relationship between the EMMF and the physical force as an attempt to evaluate the driving posture which depends on the design parameters of the wheelchair.
Expression of Reelin in cancer stem cells isolated from human glioblastoma
Creators: name: Biamonte, Filippo
name: Scicchitano, Bianca Maria
name: Sica, Gigliola
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014

description: Reelin is a large secreted extracellular matrix glycoprotein which contributes to positioning, migration and laminar organization of several central nervous system structures during neurodevelopment. Recent studies reported the expression of Reelin and its intracellular adapter protein DAB1 in neuroblastoma, where it appears to be involved in cell motility and invasiveness. Interestingly, our data obtained by immunolocalization analysis show the expression of Reelin in both tumor and peritumoral area of glioblastoma (GBM). It is known that many solid tumors may originate from cancer stem cells (CSC) which are usually resistant to common therapies and might be involved in tumor progression. Therefore, we evaluated the expression of Reelin in CSC neurospheres isolated from both tumor (GCSC) and peritumoral area (PCSC) of GBM. Immunocytochemistry analysis showed the expression of Reelin in both cell types, suggesting that this protein may contribute to neurosphere tridimensional organization and possibly to cell migration during tumor progression. This is the first evidence of Reelin expression in human GBM which might indicate a pivotal role of this protein in the regulation of tumor development. Our data may open potential avenues for GBM treatment by targeting Reelin signaling activity.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
Early perivascular clustering of dendritic cells and mast cells in human skin wounds
Creators: name: Bacci, Stefano
name: Bonelli, Aurelio
name: Romagnoli, Paolo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2010
Subjects: Mast cells; dendritic cells; wound healing

description: Italian Journal of Anatomy and Embryology, Vol 115, No 1/2 (Supplement) 2010
Role of Apolipoproten E in liver aging protection
Creators: name: Bonomini, Francesca
name: Favero, Gaia
name: Foglio, Eleonora
name: Rossini, Claudia
name: Rezzani, Rita
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: liver; ApoE; bax; sirt 1; p53

description: Aging is characterized by a progressive decline of cellular functions. Reactive oxygen species (ROS) are involved in the aging process and result mainly from nonenzymatic processes in the liver. Endogenous free radicals are generated within mitochondria and suspected to cause severe injury to mitochondrial DNA. This damaged DNA accumulates with aging. In addition, polyunsaturated fatty acids, highly sensitive to ROS, decrease in liver mitochondria from human centenarians, a feature acquired during evolution as a protective mechanism to favor longevity. Diet is considered the main environmental factor having effect on lifespan. It has a major impact on aging liver, the central metabolic organ of the body. Apolipoprotein E (apoE) null mice are a very popular model for studying spontaneous hypercholesterolemia, but only limited data are available for the role of apolipoprotein E in liver disease. The purpose of this study is to evaluate liver disease in apolipoprotein E deficient mice. For this study, apoE null mice and control mice at different ages (6 weeks and 15 months) were used. Liver morphological damage and proteins involved in oxidative stress, apoptosis and aging (Bax, Sirt 1, p53) were analyzed. ApoE deficient mice have morphological alterations that are the hallmark of liver pathogenesis, which increase with the age of the animals. In apoE null mice livers, there is also increased oxidative stress as compared to control mice at the same age and fewer antioxidant enzymes. Our findings add to the growing list of protective effects that apoE possesses.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011