cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Periodontal Infection and Cardiorespiratory Fitness in Younger Adults: Results from Continuous National Health and Nutrition Examination Survey 1999–2004
Creators: name: Thai, Ashley
name: Papapanou, Panos N.
name: Jacobs Jr., David R.
name: Desvarieux, Moïse
name: Demmer, Ryan T.
Publisher: name: Columbia University
Year: 2014
Subjects: Hypertension
Physical fitness
Periodontal disease
Public health

description: Objective

Previous studies report associations between periodontal infection and cardiorespiratory fitness but no study has examined the association among younger adults. Our objective was to study the association between clinical measures of periodontal infection and cardiorespiratory fitness levels among a population-based sample of younger adults.

Methods

The Continuous National Health and Nutrition Examination Survey 1999–2004 enrolled 2,863 participants (46% women) who received a partial-mouth periodontal examination and completed a submaximal treadmill test for the assessment of estimated VO2 max(eVO2 max ). Participants were mean±SD age 33±9 years (range = 20–49 years), 30% Hispanic, 48% White, 19% Black, and 3% other. Mean eVO2 max (mL/kg/minute) as well as eVO2 max≤32 mL/kg/minute (20th percentile) were regressed across quartiles of mean probing depth and mean attachment loss in multivariable linear and logistic regression models.

Results

After multivariable adjustment, mean eVO2 max levels±SE across quartiles of attachment loss were 39.72±0.37, 39.64±0.34, 39.59±0.36, and 39.85±0.39 (P = 0.99). Mean eVO2 max±SE across quartiles of probing depth were 39.57±0.32, 39.78±0.38, 39.19±0.25, and 40.37±0.53 (P = 0.28). Similarly, multivariable adjusted mean eVO2 max values were similar between healthy participants vs. those with moderate/severe periodontitis: 39.70±0.21 vs. 39.70±0.90 (P = 1.00). The odds ratio (OR) for low eVO2 max comparing highest vs. lowest quartile of attachment loss = 0.89[95% CI 0.64–1.24]. The OR for comparing highest vs. lowest probing depth quartile = 0.77[95% CI 0.51–1.15].

Conclusion

Clinical measures of periodontal infection were not related to cardiorespiratory fitness in a sample of generally healthy younger adults.
Tunable symmetry breaking and helical edge transport in a graphene quantum spin Hall state
Creators: name: Young, A. F.
name: Sanchez-Yamagishi, J. D.
name: Hunt, B.
name: Choi, S. H.
name: Watanabe, K.
name: Taniguchi, T.
name: Ashoori, R. C.
name: Jarillo-Herrero, P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Low-dimensional electronic systems have traditionally been obtained by electrostatically confining electrons, either in heterostructures or in intrinsically nanoscale materials such as single molecules, nanowires, and graphene. Recently, a new paradigm has emerged with the advent of symmetry-protected surface states on the boundary of topological insulators, enabling the creation of electronic systems with novel properties. For example, time reversal symmetry (TRS) endows the massless charge carriers on the surface of a three-dimensional topological insulator with helicity, locking the orientation of their spin relative to their momentum. Weakly breaking this symmetry generates a gap on the surface, resulting in charge carriers with finite effective mass and exotic spin textures. Analogous manipulations of the one-dimensional boundary states of a two-dimensional topological insulator are also possible, but have yet to be observed in the leading candidate materials. Here, we demonstrate experimentally that charge neutral monolayer graphene displays a new type of quantum spin Hall (QSH) effect, previously thought to exist only in TRS topological insulators, when it is subjected to a very large magnetic field angled with respect to the graphene plane. Unlike in the TRS case, the QSH presented here is protected by a spin-rotation symmetry that emerges as electron spins in a half-filled Landau level are polarized by the large in-plane magnetic field. The properties of the resulting helical edge states can be modulated by balancing the applied field against an intrinsic antiferromagnetic instability, which tends to spontaneously break the spin-rotation symmetry. In the resulting canted antiferromagnetic (CAF) state, we observe transport signatures of gapped edge states, which constitute a new kind of one-dimensional electronic system with tunable band gap and associated spin-texture.
description: 15 pages, 10 figures including supplementary information
Stylodipus telum
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Dipodidae
Stylodipus
Stylodipus telum

description: Stylodipus telum (Lichtenstein, 1823). Naturh. Abh. Eversmann's Reise, p. 120. TYPE LOCALITY: U.S. S. R., Kazakhstan, steppe at N.E. shore of Aral Sea. DISTRIBUTION: E. Ukraine, N. Caucasus, and Kazakhstan (U.S. S.R.); Sinkiang, Ningsiahui, and Inner Mongolia (China); S. Mongolia. COMMENT: Includes andrewsi, which was considered a distinct species by Sokolov and Orlov, 1980:187; see Corbet, 1978:153. ISIS NUMBER: 5301410016007001001.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 569, DOI: 10.5281/zenodo.7353039
description: {"references": ["Sokolov, V. E., and V. N. Orlov. 1980. Opredelitel' mlekopitayushchickh Mongol'skoi Narodnoi Respubliki [Guide to the mammals of the Mongolian People's Republic]. Nauka, Moscow, 351 pp. (in Russian)."]}
Micronutrient Intakes among Women of Reproductive Age in Vietnam
Creators: name: Nguyen, Phuong H.
name: Nguyen, Hieu
name: Gonzalez-Casanova, Ines
name: Copeland, Erika
name: Strizich, Garrett
name: Lowe, Alyssa
name: Pham, Hoa
name: Truong, Truong V.
name: Nguyen, Son
name: Martorell, Reynaldo
name: Ramakrishnan, Usha
Publisher: name: Columbia University
Year: 2014
Subjects: Women--Nutrition
Nutrition--Evaluation
Trace elements in nutrition
Public health

description: Background:

Micronutrient deficiencies are a public health concern worldwide negatively affecting maternal and child health outcomes. The primary underlying causes of micronutrient deficiencies are insufficient intake and poor bioavailability of micronutrients. However, reliable data on micronutrient intakes are sparse. The objectives of this study were to identify the key local food sources providing the majority of micronutrients and assess the adequacy and determinants of micronutrient intakes.

Methods:

The study used data from a survey of 4,983 rural women of reproductive age (WRA) participating in a preconception micronutrient supplementation trial in Vietnam. Micronutrient intakes were assessed using a validated 107-item semi-quantitative food-frequency questionnaire. Multivariate linear and logistic regression analyses were used to examine the association between socioeconomic status and micronutrient intakes.

Results:

Starchy staples were the main source of iron and zinc (37% and 54%, respectively) with only a small proportion from meat (10% and 18%, respectively). The primary source of folate and vitamin A were vegetables; vitamin B12 came from meat and eggs. The proportion of the population with intakes below the estimated average requirement was 25% for iron, 16% for zinc, 54% for folate, 64% for vitamin B12 and 27% for vitamin A. Socioeconomic status was the main determinant of micronutrient intakes. WRA in the highest quintile consumed 26% more iron, 19% more zinc, 36% more folate, 82% more vitamin B12 and 47% more vitamin A compared to those in the lowest quintile. Women in the upper quintiles of SES were more likely to obtain nutrients from more nutritious and higher bioavailable foods than those in the lowest quintile.

Conclusions:

Underprivileged women were at increased risk for insufficient micronutrient intakes due to poor diet quality. Targeted efforts to promote the consumption of local nutrient rich foods along with educational programs and social development are needed.
Resonant electron tunneling in a tip-controlled potential landscape
Creators: name: Pascher, N.
name: Timpu, F.
name: Rossler, C.
name: Ihn, T.
name: Ensslin, K.
name: Reichel, C.
name: Wegscheider, W.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: By placing the biased tip of an atomic force microscope at a specific position above a semiconductor surface we can locally shape the potential landscape. Inducing a local repulsive potential in a two dimensional electron gas near a quantum point contact one obtains a potential minimum which exhibits a remarkable behavior in transport experiments at high magnetic fields and low temperatures. In such an experiment we observe distinct and reproducible oscillations in the measured conductance as a function of magnetic field, voltages and tip position. They follow a systematic behavior consistent with a resonant tunneling mechanism. From the periodicity in magnetic field we can find the characteristic width of this minimum to be of the order of 100 nm. Surprisingly, this value remains almost the same for different values of the bulk filling factors, although the tip position has to be adjusted by distances of the order of one micron.
Unified Models of Molecular Emission from Class 0 Protostellar Outflow Sources
Creators: name: Rawlings, J. M. C.
name: Redman, M. P.
name: Carolan, P. B.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Low mass star-forming regions are more complex than the simple spherically symmetric approximation that is often assumed. We apply a more realistic infall/outflow physical model to molecular/continuum observations of three late Class 0 protostellar sources with the aims of (a) proving the applicability of a single physical model for all three sources, and (b) deriving physical parameters for the molecular gas component in each of the sources. We have observed several molecular species in multiple rotational transitions. The observed line profiles were modelled in the context of a dynamical model which incorporates infall and bipolar outflows, using a three dimensional radiative transfer code. This results in constraints on the physical parameters and chemical abundances in each source. Self-consistent fits to each source are obtained. We constrain the characteristics of the molecular gas in the envelopes as well as in the molecular outflows. We find that the molecular gas abundances in the infalling envelope are reduced, presumably due to freeze-out, whilst the abundances in the molecular outflows are enhanced, presumably due to dynamical activity. Despite the fact that the line profiles show significant source-to-source variation, which primarily derives from variations in the outflow viewing angle, the physical parameters of the gas are found to be similar in each core.
description: MNRAS 12 pages, 16 figures
Molecular and Neurodevelopmental Benefits to Children of Closure of a Coal Burning Power Plant in China
Creators: name: Tang, Deliang
name: Lee, Joan
name: Muirhead, Loren
name: Li, Ting Yu
name: Qu, Lirong
name: Yu, Jie
name: Perera, Frederica P.
Publisher: name: Columbia University
Year: 2014
Subjects: Children
DNA--Methylation
Air--Pollution
Neurology

description: Polycyclic aromatic hydrocarbons (PAH) are major toxic air pollutants released during incomplete combustion of coal. PAH emissions are especially problematic in China because of their reliance on coal-powered energy. The prenatal period is a window of susceptibility to neurotoxicants. To determine the health benefits of reducing air pollution related to coal-burning, we compared molecular biomarkers of exposure and preclinical effects in umbilical cord blood to neurodevelopmental outcomes from two successive birth cohorts enrolled before and after a highly polluting, coal-fired power plant in Tongliang County, China had ceased operation. Women and their newborns in the two successive cohorts were enrolled at the time of delivery. We measured PAH-DNA adducts, a biomarker of PAH-exposure and DNA damage, and brain-derived neurotrophic factor (BDNF), a protein involved in neuronal growth, in umbilical cord blood. At age two, children were tested using the Gesell Developmental Schedules (GDS). The two cohorts were compared with respect to levels of both biomarkers in cord blood as well as developmental quotient (DQ) scores across 5 domains. Lower levels of PAH-DNA adducts, higher concentrations of the mature BDNF protein (mBDNF) and higher DQ scores were seen in the 2005 cohort enrolled after closure of the power plant. In the two cohorts combined, PAH-DNA adducts were inversely associated with mBDNF as well as scores for motor (p = 0.05), adaptive (p = 0.022), and average (p = 0.014) DQ. BDNF levels were positively associated with motor (p = 0.018), social (p = 0.001), and average (p = 0.017) DQ scores. The findings indicate that the closure of a coal-burning plant resulted in the reduction of PAH-DNA adducts in newborns and increased mBDNF levels that in turn, were positively associated with neurocognitive development. They provide further evidence of the direct benefits to children's health as a result of the coal plant shut down, supporting clean energy and environmental policies in China and elsewhere.
Breast health knowledge and awareness among stakeholders in women’s rugby
Creators: name: Bibby, Kilian
name: Kenny, Ian
name: Cahalan, Róisín
name: Guilfoyle, Lauren
name: Comyns, Thomas M.
Publisher: name: University of Limerick
Year: 2025
Subjects: classificationCode: 4207
subject: Sports science and exercise
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: This study interviewed stakeholders involved with women’s Rugby in Ireland consisting of male and female coaches (n= 5), physiotherapists (n =3), strength and conditioning coaches (n =3) and female players (n =3) on their knowledge and awareness of breast health issues. The findings indicate overall limited breast health knowledge and awareness amongst interviewees. Breast health issues can have potential future health complications such as fat necrosis or tissue scaring. The primary barrier to reporting breast health issues ascertained was due to the sensitive nature of the topic. The results further highlighted a lack of reporting pathways and treatment options for breast health problems among support staff overall. Additionally, this study indicates that current breast protective measures were not evidence-based, requiring further research. The findings underscored the need for targeted education, preferably by a female educator, on breast health issues for female players, coaches, and support staff, and tailored to stakeholder preferences to improve efficacy
The Star Formation Law in Molecule-Poor Galaxies
Creators: name: Krumholz, Mark R.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: In this paper, I investigate the processes that regulate the rate of star formation in regions of galaxies where the neutral interstellar medium is predominantly composed of non-star-forming HI. In such regions, found today predominantly in low-metallicity dwarf galaxies and in the outer parts of large spirals, the star formation rate per unit area and per unit mass is much smaller than in more molecule-rich regions. While in molecule-rich regions the ultraviolet radiation field produced by efficient star formation forces the density of the cold neutral medium to a value set by two-phase equilibrium, I show that the low rates of star formation found in molecule-poor regions preclude this condition. Instead, the density of the cold neutral gas is set by the requirements of hydrostatic balance. Using this result, I extend the Krumholz, McKee, & Tumlinson model for star formation and the atomic to molecular transition to the molecule-poor regime. This "KMT+" model matches a wide range of observations of the star formation rate and the balance between the atomic and molecular phases in dwarfs and in the outer parts of spirals, and is well-suited to implementation as a subgrid recipe for star formation in cosmological simulations and semi-analytic models. I discuss the implications of this model for star formation over cosmological times.
description: 18 pages, 9 figures, accepted for publication in MNRAS
Disputatio Ivris Civilis Et Pvblici De Appellationibvs In Cavsis Non Appellabilibvs, Nostris: Von Appellationen in Sachen, da sonsten keine Appellation statt findet, sowohl vor Kayserl. Cammer, als auch andern geist- und weltlichen Gerichten; 1755
Creators: name: Wildvogel, Christian
name: Haselhuhn, Johann Georg
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2015

description: Vorlageform des Erscheinungsvermerks: Ienae, Prostat Apvd I. B. Hellervm, 1755.
DNA Methylation of Heparanase Promoter Influences Its Expression and Associated with the Progression of Human Breast Cancer
Creators: name: Jiao, Fei
name: Bai, Shi-Yu
name: Ma, Ying
name: Yan, Zhong-Hai
name: Yue, Zhen
name: Yu, Yuan
name: Wang, Xin
name: Wang, Juan
Publisher: name: Columbia University
Year: 2014
Subjects: Breast--Cancer
Polymerase chain reaction
DNA--Methylation
Biochemistry

description: Heparanase promotes tumor invasion and metastasis in several malignancies including breast cancer. However, the roles and regulation mechanisms of heparanase during breast cancer progression are still not fully understood. The aim of this study is to determine the differential regulation of heparanase gene expression in specific stages of breast cancer by DNA methylation. We detected levels of heparanase expression and DNA methylation patterns of its promoter in breast cancer cell lines (MCF-7 and MDA-MB-435) and clinical tissues, respectively. It has been observed that heparanase is highly expressed in the invasive MDA-MB-435 cells with low methylation modification in the heparanase promoter. In contrast, lower expression of heparanase in MCF-7 cells is accompanied by higher methylation in the promoter. Treatment of MCF-7 cells with 5-aza-2′-deoxycytidine (5-aza-dC), a potent demethylating agent, results in induction of heparanase expression and higher invasion potential in vitro and leads to an advantage of tumor formation in vivo. In 54 tissue samples, cancer samples at late stages (stage IV) showed the highest heparanase expression accomplished by little DNA methylation. On the contrary, methylation prevalence is highest in normal tissue and inversely correlated with heparanase expression. A significant correlation between DNA methylation and clinical stage was demonstrated (p = 0.012). Collectively, these results demonstrate that DNA methylation play the regulation role in heparanase gene in different stages of breast cancer and present a direct effect on tumor progression.
Higher-order structure and epidemic dynamics in clustered networks
Creators: name: Ritchie, Martin
name: Berthouze, Luc
name: House, Thomas
name: Kiss, Istvan Z.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Clustering is typically measured by the ratio of triangles to all triples, open or closed. Generating clustered networks, and how clustering affects dynamics on networks, is reasonably well understood for certain classes of networks \cite{vmclust, karrerclust2010}, e.g., networks composed of lines and non-overlapping triangles. In this paper we show that it is possible to generate networks which, despite having the same degree distribution and equal clustering, exhibit different higher-order structure, specifically, overlapping triangles and other order-four (a closed network motif composed of four nodes) structures. To distinguish and quantify these additional structural features, we develop a new network metric capable of measuring order-four structure which, when used alongside traditional network metrics, allows us to more accurately describe a network's topology. Three network generation algorithms are considered: a modified configuration model and two rewiring algorithms. By generating homogeneous networks with equal clustering we study and quantify their structural differences, and using SIS (Susceptible-Infected-Susceptible) and SIR (Susceptible-Infected-Recovered) dynamics we investigate computationally how differences in higher-order structure impact on epidemic threshold, final epidemic or prevalence levels and time evolution of epidemics. Our results suggest that characterising and measuring higher-order network structure is needed to advance our understanding of the impact of network topology on dynamics unfolding on the networks.
Risk Factors for Death in 632 Patients with Sickle Cell Disease in the United States and United Kingdom
Creators: name: Gladwin, Mark T.
name: Barst, Robyn J.
name: R. Gibbs, J. Simon
name: Hildesheim, Mariana
name: Sachdev, Vandana
name: Nouraie, Mehdi
name: Hassell, Kathryn L.
name: Little, Jane A.
name: Schraufnagel, Dean E.
name: Krishnamurti, Lakshmanan
name: Novelli, Enrico
name: Girgis, Reda E.
name: Morris, Claudia R.
name: Berman Rosenzweig, Erika S.
name: Badesch, David B.
name: Lanzkron, Sophie
name: Castro, Oswaldo L.
name: Taylor VI, James G.
name: Goldsmith, Jonathan C.
name: Kato, Gregory J.
name: Gordeuk, Victor R.
name: Machado, Roberto F.
name: Walk-PHaSST Investigators And Patients
Publisher: name: Columbia University
Year: 2014
Subjects: Pulmonary hypertension
Regression analysis
Sickle cell anemia
Public health

description: Background

The role of pulmonary hypertension as a cause of mortality in sickle cell disease (SCD) is controversial.

Methods and Results

We evaluated the relationship between an elevated estimated pulmonary artery systolic pressure and mortality in patients with SCD. We followed patients from the walk-PHaSST screening cohort for a median of 29 months. A tricuspid regurgitation velocity (TRV)≥3.0 m/s cuttof, which has a 67–75% positive predictive value for mean pulmonary artery pressure ≥25 mm Hg was used. Among 572 subjects, 11.2% had TRV≥3.0 m/sec. Among 582 with a measured NT-proBNP, 24.1% had values ≥160 pg/mL. Of 22 deaths during follow-up, 50% had a TRV≥3.0 m/sec. At 24 months the cumulative survival was 83% with TRV≥3.0 m/sec and 98% with TRV<3.0 m/sec (p<0.0001). The hazard ratios for death were 11.1 (95% CI 4.1–30.1; p<0.0001) for TRV≥3.0 m/sec, 4.6 (1.8–11.3; p = 0.001) for NT-proBNP≥160 pg/mL, and 14.9 (5.5–39.9; p<0.0001) for both TRV≥3.0 m/sec and NT-proBNP≥160 pg/mL. Age >47 years, male gender, chronic transfusions, WHO class III–IV, increased hemolytic markers, ferritin and creatinine were also associated with increased risk of death.

Conclusions

A TRV≥3.0 m/sec occurs in approximately 10% of individuals and has the highest risk for death of any measured variable.

The study is registered in ClinicalTrials.gov with identifier

NCT00492531
RAD9 deficiency enhances radiation induced bystander DNA damage and transcriptomal response
Creators: name: Ghandhi, Shanaz
name: Ponnaiya, Brian
name: Panigrahi, Sunil Kumar
name: Hopkins, Kevin M.
name: Cui, Qingping
name: Hei, Tom K.
name: Amundson, Sally A.
name: Lieberman, Howard B.
Publisher: name: Columbia University
Year: 2014
Subjects: subject: Chromosome abnormalities
subject: Gene expression
subject: Ionizing radiation
subject: Genetics
subject: FOS: Biological sciences

description: Background
Radiation induced bystander effects are an important component of the overall response of cells to irradiation and are associated with human health risks. The mechanism responsible includes intra-cellular and inter-cellular signaling by which the bystander response is propagated. However, details of the signaling mechanism are not well defined.

Methods
We measured the bystander response of Mrad9 +/+ and Mrad9 −/− mouse embryonic stem cells, as well as human H1299 cells with inherent or RNA interference-mediated reduced RAD9 levels after exposure to 1 Gy α particles, by scoring chromosomal aberrations and micronuclei formation, respectively. In addition, we used microarray gene expression analyses to profile the transcriptome of directly irradiated and bystander H1299 cells.

Results
We demonstrated that Mrad9 null enhances chromatid aberration frequency induced by radiation in bystander mouse embryonic stem cells. In addition, we found that H1299 cells with reduced RAD9 protein levels showed a higher frequency of radiation induced bystander micronuclei formation, compared with parental cells containing inherent levels of RAD9. The enhanced bystander response in human cells was associated with a unique transcriptomic profile. In unirradiated cells, RAD9 reduction broadly affected stress response pathways at the mRNA level; there was reduction in transcript levels corresponding to genes encoding multiple members of the UVA-MAPK and p38MAPK families, such as STAT1 and PARP1, suggesting that these signaling mechanisms may not function optimally when RAD9 is reduced. Using network analysis, we found that differential activation of the SP1 and NUPR1 transcriptional regulators was predicted in directly irradiated and bystander H1299 cells. Transcription factor prediction analysis also implied that HIF1α (Hypoxia induced factor 1 alpha) activation by protein stabilization in irradiated cells could be a negative predictor of the bystander response, suggesting that local hypoxic stress experienced by cells directly exposed to radiation may influence whether or not they will elicit a bystander response in neighboring cells.
Hystricidae Fischer de Waldheim 1817
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Hystricidae

description: Family Hystricidae REVIEWED BY: J. E. Bucher (JEB). COMMENT: Reviewed by Mohr, 1965, Altweltliche Stachelschweine, Wittenberg Lutherstadt: Ziemsen, 164 pp. ISIS NUMBER: 5301410017000000000.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 569, DOI: 10.5281/zenodo.7353039
description: {"references": ["Mohr, E. 1965. Altweltliche Stachelschweine. Ziemsen Verlag, Wittenberg Lutherstadt, 164 pp."]}
The Gould's Belt Very Large Array Survey I: The Ophiuchus complex
Creators: name: Dzib, Sergio A.
name: Loinard, Laurent
name: Mioduszewski, Amy J.
name: Rodríguez, Luis F.
name: Ortiz-León, Gisela N.
name: Pech, Gerardo
name: Rivera, Juana L.
name: Torres, Rosa M.
name: Boden, Andrew F.
name: Hartmann, Lee
name: Evans, Neal J.
name: Briceño, Cesar
name: Tobin, John
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present large-scale ($\sim$ 2000 square arcminutes), deep ($\sim$ 20 $μ$Jy), high-resolution ($\sim$ 1$''$) radio observations of the Ophiuchus star-forming complex obtained with the Karl G.\ Jansky Very Large Array at $λ$ = 4 and 6 cm. In total, 189 sources were detected, 56 of them associated with known young stellar sources, and 4 with known extragalactic objects; the other 129 remain unclassified, but most of them are most probably background quasars. The vast majority of the young stars detected at radio wavelengths have spectral types K or M, although we also detect 4 objects of A/F/B types and 2 brown dwarf candidates. At least half of these young stars are non-thermal (gyrosynchrotron) sources, with active coronas characterized by high levels of variability, negative spectral indices, and (in some cases) significant circular polarization. As expected, there is a clear tendency for the fraction of non-thermal sources to increase from the younger (Class 0/I or flat spectrum) to the more evolved (Class III or weak line T Tauri) stars. The young stars detected both in X-rays and at radio wavelengths broadly follow a Güdel-Benz relation, but with a different normalization than the most radio-active types of stars. Finally, we detect a $\sim$ 70 mJy compact extragalactic source near the center of the Ophiuchus core, which should be used as gain calibrator for any future radio observations of this region.
description: Accepted for publication in The Astrophysical Journal. 31 pages, 8 figure, 5 tables
Wnt5a regulates dental follicle stem/progenitor cells of the periodontium
Creators: name: Xiang, Lusai
name: Chen, Mo
name: He, Ling
name: Cai, Bin
name: Du, Yu
name: Zhang, Xinchun
name: Zhou, Chen
name: Wang, Chenglin
name: Mao, Jeremy J.
name: Ling, Junqi
Publisher: name: Columbia University
Year: 2014
Subjects: Stem cells
Child development
Periodontics
Biochemistry

description: Introduction
Dental follicle gives rise to one or several tissues of the periodontium including the periodontal ligament, cementum and/or alveolar bone. Whether Wnt5a is expressed in the postnatal periodontium or regulates dental follicle stem/progenitor cells is unknown.

Methods
Dental follicle stem/progenitor cells were isolated from postnatal day 1 (p1) to p11 from rat mandibular first molars. Immunolocalization mapped Wnt5a expression in the alveolar bone, periodontal ligament, and the developing ameloblast and odontoblast layers. Mononucleated and adherent cells were isolated from p7 dental follicle. Wnt5a was overexpressed in dental follicle stem/progenitor cells to study their proliferation, osteogenic differentiation and migration behavior, with subpopulations of native dental follicle stem/progenitor cells as controls, using real-time PCR (Taqman), Lenti-viral transfection, Western blotting and immunofluorescence.

Results
Wnt5a was expressed consistently in p1 to p11 rat peridontium. Native, p7 dental follicle stem/progenitor cells had modest ability to mineralize in the tested 14 days. Even in chemically defined osteogenesis medium, dental follicle stem/progenitor cells only showed modest mineralization. Upon addition of 300 ng/mL Wnt5a protein in osteogenesis medium, dental follicle stem/progenitor cells displayed mineralization that was still unremarkable. Chemically induced or Wnt5a-induced mineralization of dental follicle cells only occurred sparsely. Combination of Wnt5a with 100 ng/mL BMP2 finally prompted dental follicle stem/progenitor cells to produce robust mineralization with elevated expression of Runx2, alkaline phosphatase, collagen 1α1 and osteocalcin. Thus, native dental follicle stem/progenitor cells or some of their fractions may be somewhat modest in mineralization. Strikingly, Wnt5a protein significantly augmented RANKL ligand, suggesting putative regulatory roles of dental follicle stem/progenitor cells for the monocyte/osteoclast lineage and potential involvement in alveolar bone remodeling and/or resorption. P-Jnk1/2 was activated in Wnt5a overexpressed dental follicle cells; conversely, exposure to SP600125, a c-Jun N-terminal kinase (JNK) inhibitor attenuated Runx2, collagen 1α1 and osteocalcin expression either in the presence or absence of Wnt5a. Wnt5a overexpression in dental follicle stem/progenitor cells significantly reduced their proliferation rates, but robustly augmented their migration capacity.

Conclusions
These findings provide a glimpse of Wnt5a’s putative roles in dental follicle stem/progenitor cells and the periodontium with implications in periodontal disease, tooth eruption, dental implant bone healing and orthodontic tooth movement.
title: Manuel, der falsche Freund; 1799
title: Ein Trauerspiel in fünf Aufzügen
titleType: Subtitle
Creators: name: (:Unav)
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2015

description: In Fraktur. - Letzte Textzeile: "decket." Nicht identisch mit abweichender Ausgabe (ÖNB): dort "Schleier decket."
Comparing Chemistry to Outcome: The Development of a Chemical Distance Metric, Coupled with Clustering and Hierarchal Visualization Applied to Macromolecular Crystallography
Creators: name: Bruno, Andrew E.
name: Ruby, Amanda M.
name: Luft, Joseph R.
name: Grant, Thomas D.
name: Seetharaman, Jayaraman
name: Montelione, Gaetano T.
name: Hunt, John F.
name: Snell, Edward H.
Publisher: name: Columbia University
Year: 2014
Subjects: Phosphates
Macromolecules--Structure
Crystals
Chemistry

description: Many bioscience fields employ high-throughput methods to screen multiple biochemical conditions. The analysis of these becomes tedious without a degree of automation. Crystallization, a rate limiting step in biological X-ray crystallography, is one of these fields. Screening of multiple potential crystallization conditions (cocktails) is the most effective method of probing a proteins phase diagram and guiding crystallization but the interpretation of results can be time-consuming. To aid this empirical approach a cocktail distance coefficient was developed to quantitatively compare macromolecule crystallization conditions and outcome. These coefficients were evaluated against an existing similarity metric developed for crystallization, the C6 metric, using both virtual crystallization screens and by comparison of two related 1,536-cocktail high-throughput crystallization screens. Hierarchical clustering was employed to visualize one of these screens and the crystallization results from an exopolyphosphatase-related protein from Bacteroides fragilis, (BfR192) overlaid on this clustering. This demonstrated a strong correlation between certain chemically related clusters and crystal lead conditions. While this analysis was not used to guide the initial crystallization optimization, it led to the re-evaluation of unexplained peaks in the electron density map of the protein and to the insertion and correct placement of sodium, potassium and phosphate atoms in the structure. With these in place, the resulting structure of the putative active site demonstrated features consistent with active sites of other phosphatases which are involved in binding the phosphoryl moieties of nucleotide triphosphates. The new distance coefficient, CDcoeff, appears to be robust in this application, and coupled with hierarchical clustering and the overlay of crystallization outcome, reveals information of biological relevance. While tested with a single example the potential applications related to crystallography appear promising and the distance coefficient, clustering, and hierarchal visualization of results undoubtedly have applications in wider fields.
Direct Observation of Fragmentation in a Disordered, Strongly Interacting Fermi Gas
Creators: name: Krinner, Sebastian
name: Stadler, David
name: Meineke, Jakob
name: Brantut, Jean-Philippe
name: Esslinger, Tilman
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Describing the behaviour of strongly interacting particles in the presence of disorder is among the most challenging problems in quantum many-body physics. The controlled setting of cold atom experiments provides a new avenue to address these challenges [1], complementing studies in solid state physics, where a number of puzzling findings have emerged in experiments using superconducting thin films [2,3]. Here we investigate a strongly interacting thin film of an atomic Fermi gas subject to a random potential. We use high-resolution in-situ imaging [4-7] to resolve the atomic density at the length scale of a single impurity, which would require scanning probe techniques in solid state physics [8]. This allows us to directly observe the fragmentation of the density profile and to extract its percolation properties. Transport measurements in a two-terminal configuration indicate that the fragmentation process is accompanied by a breakdown of superfluidity. Our results suggest that percolation of paired atoms is responsible for the loss of superfluidity, and that disorder is able to increase the binding energy of pairs.
Atherurus F. Cuvier 1829
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Hystricidae
Atherurus

description: Atherurus F. Cuvier, 1829. Diet. Sei. Nat., 59:483. ISIS NUMBER: 5301410017001000000.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 569, DOI: 10.5281/zenodo.7353039
Charmonium spectral functions from 2+1 flavour lattice QCD
Creators: name: Borsanyi, Szabolcs
name: Durr, Stephan
name: Fodor, Zoltan
name: Hoelbling, Christian
name: Katz, Sandor D.
name: Krieg, Stefan
name: Mages, Simon
name: Nogradi, Daniel
name: Pasztor, Attila
name: Schafer, Andreas
name: Szabo, Kalman K.
name: Toth, Balint C.
name: Trombitas, Norbert
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Finite temperature charmonium spectral functions in the pseudoscalar and vector channels are studied in lattice QCD with 2+1 flavours of dynamical Wilson quarks, on fine isotropic lattices (with a lattice spacing of 0.057 fm), with a non-physical pion mass of $m_π \approx$ 545 MeV. The highest temperature studied is approximately $1.4 T_c$. Up to this temperature no significant variation of the spectral function is seen in the pseudoscalar channel. The vector channel shows some temperature dependence, which seems to be consistent with a temperature dependent low frequency peak related to heavy quark transport, plus a temperature independent term at ω>0. These results are in accord with previous calculations using the quenched approximation.
description: 17 pages, 9 figures, 2 tables
Bioluminescence and repeated deep-sea colonisation shaped the diversification and body size evolution of squaliform sharks
Creators: name: Marion, Alexis
name: Guinot, Guillaume
name: Condamine, Fabien
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 310403
subject: Biological adaptation
classificationCode: 310412
subject: Speciation and extinction

description: Figshare repository for "Bioluminescence and repeated deep-sea colonisation shaped the diversification and body size evolution of squaliform sharks".This repository contains four zipped folders:The folder containing all raw data required to perform the analyses (Raw_data.zip)The output from each PyRate analysis (Results_PyRate)The output from each corHMM analysis (Results_corHMM)The output from each continuous trait analysis (Results_cont_trait)Code is available on GitHub "https://github.com/Alexis-Marion/Bioluminescence-Diversification-Sharks"
Concentration-Dependent Exchange of Replication Protein A on Single-Stranded DNA Revealed by Single-Molecule Imaging
Creators: name: Gibb, Bryan
name: Ye, Ling Feng
name: Gergoudis, Stephanie C.
name: Kwon, YoungHo
name: Niu, Hengyao
name: Sung, Patrick
name: Greene, Eric C.
Publisher: name: Columbia University
Year: 2014
Subjects: subject: Protein binding
subject: DNA--Metabolism
subject: Saccharomyces cerevisiae--Genetics
subject: Genetics
subject: FOS: Biological sciences

description: Replication protein A (RPA) is a ubiquitous eukaryotic single-stranded DNA (ssDNA) binding protein necessary for all aspects of DNA metabolism involving an ssDNA intermediate, including DNA replication, repair, recombination, DNA damage response and checkpoint activation, and telomere maintenance [1], [2], [3]. The role of RPA in most of these reactions is to protect the ssDNA until it can be delivered to downstream enzymes. Therefore a crucial feature of RPA is that it must bind very tightly to ssDNA, but must also be easily displaced from ssDNA to allow other proteins to gain access to the substrate. Here we use total internal reflection fluorescence microscopy and nanofabricated DNA curtains to visualize the behavior of Saccharomyces cerevisiae RPA on individual strands of ssDNA in real-time. Our results show that RPA remains bound to ssDNA for long periods of time when free protein is absent from solution. In contrast, RPA rapidly dissociates from ssDNA when free RPA is present in solution allowing rapid exchange between the free and bound states. In addition, the S. cerevisiae DNA recombinase Rad51 and E. coli single-stranded binding protein (SSB) also promote removal of RPA from ssDNA. These results reveal an unanticipated exchange between bound and free RPA suggesting a binding mechanism that can confer exceptionally slow off rates, yet also enables rapid displacement through a direct exchange mechanism that is reliant upon the presence of free ssDNA-binding proteins in solution. Our results indicate that RPA undergoes constant microscopic dissociation under all conditions, but this is only manifested as macroscopic dissociation (i.e. exchange) when free proteins are present in solution, and this effect is due to mass action. We propose that the dissociation of RPA from ssDNA involves a partially dissociated intermediate, which exposes a small section of ssDNA allowing other proteins to access to the DNA.
Atherurus africanus Gray 1842
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Hystricidae
Atherurus
Atherurus africanus

description: Atherurus africanus Gray, 1842. Ann. Mag. Nat. Hist., 10:261. TYPE LOCALITY: Sierra Leone. DISTRIBUTION: Gambia; Sierra Leone; Liberia; Ghana; Zaire; Kenya; Uganda; S. Sudan. COMMENT: Includes centralis and turneri; see Misonne, 1974, Part 6:8. ISIS NUMBER: 5301410017001001001 as A. africanus. 5301410017001002001 as A. centralis. 5301410017001004001 as A. turneri.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 569, DOI: 10.5281/zenodo.7353039
description: {"references": ["Misonne, X. 1974. Order Rodentia. Part 6. Pp. 1 - 39, in The mammals of Africa: An identification manual (J. Meester and H. W. Setzer, eds.). [issued 10 Sep 1974]. Smithsonian Institution Press, Washington, D. C., not continuously paginated."]}
Mathematical modeling and analysis for the chemotactic diffusion in porous media with incompressible Navier-Stokes equations over bounded domain
Creators: name: Ma, Fugui
name: Tian, Wenyi
name: Deng, Weihua
Publisher: name: arXiv
Year: 2024
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35Q92, 35Q35, 35R11, 35A01, 35A02, 35B44

description: Myxobacteria aggregate and generate fruiting bodies in the soil to survive under starvation conditions. Considering soil as a porous medium, the biological mechanism and dynamic behavior of myxobacteria and slime (chemoattractants) affected by favorable environments in the soil can not be well characterized by the classical full parabolic Keller-Segel system combined with the incompressible Navier-Stokes equations. In this work, we employ the continuous time random walk (CTRW) approach to characterize the diffusion behavior of myxobacteria and slime in porous media at the microscale, and develop a new macroscopic model named as the time-fractional Keller-Segel system. Then it is coupled with the incompressible Navier-Stokes equations through transport and buoyancy, resulting in the TF-KSNS system, which reveals the biological mechanism from micro to macro and then appropriately describes the dynamic behavior of the chemotactic diffusion of myxobacteria and slime in the soil. In addition, we demonstrate that the TF-KSNS system associated with initial and no-flux/no-flux/Dirichlet boundary conditions over smoothly bounded domain in $\mathbb{R}^{d}$ ($d\geq2$) admits a local well-posed mild solution, which continuously depends on the initial data with proper regularity under a small initial condition. Moreover, the blow-up of the mild solution is rigorously investigated.
Additional Invariants and Statistical Equilibria for the 2D Euler Equations on a spherical domain
Creators: name: Herbert, Corentin
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The role of the domain geometry for the statistical mechanics of 2D Euler flows is investigated. It is shown that for a spherical domain, there exists invariant subspaces in phase space which yield additional angular momentum, energy and enstrophy invariants. The microcanonical measure taking into account these invariants is built and a mean-field, Robert-Sommeria-Miller theory is developed in the simple case of the energy-enstrophy measure. The variational problem is solved analytically and a partial energy condensation is obtained. The thermodynamic properties of the system are also discussed.
Atherurus macrourus
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Hystricidae
Atherurus
Atherurus macrourus

description: Atherurus macrourus (Linnaeus, 1758). Syst. Nat., 10th ed., 1:57. REVIEWED BY: S. Wang (SW). TYPE LOCALITY: Malaysia, Malacca. DISTRIBUTION: Assam (India), Szechwan, Yunnan, Hupei, and Hainan (China) to Malaya, Sumatra, and adjacent islands. COMMENT: Includes retardatus and angustiramus; see Van Weers, 1977, Beaufortia, 26(336):205-230. ISIS NUMBER: 5301410017001003001.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 569, DOI: 10.5281/zenodo.7353039
description: {"references": ["van Weers, D. J. 1977. Notes on southeast Asian porcupines (Hystricidae, Rodentia) II. On the taxonomy of the genus Atherurus F. Cuvier. Beaufortia (University of Amsterdam), 26 (336): 205 - 230."]}