cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains.
Creators: name: Manojkumar Puthenveedu
name: Lauffer, Benjamin
name: Temkin, Paul
name: Vistein, Rachel
name: Carlton, Peter
name: Thorn, Kurt
name: Taunton, Jack
name: Weiner, Orion D.
name: Parton, Robert G.
name: Zastrow, Mark Von
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The functional consequences of signaling receptor endocytosis are determined by the endosomal sorting of receptors between degradation and recycling pathways. How receptors recycle efficiently, in a sequence-dependent manner that is distinct from bulk membrane recycling, is not known. Here, in live cells, we visualize the sorting of a prototypical sequence-dependent recycling receptor, the beta-2 adrenergic receptor, from bulk recycling proteins and the degrading delta-opioid receptor. Our results reveal a remarkable diversity in recycling routes at the level of individual endosomes, and indicate that sequence-dependent recycling is an active process mediated by distinct endosomal subdomains distinct from those mediating bulk recycling. We identify a specialized subset of tubular microdomains on endosomes, stabilized by a highly localized but dynamic actin machinery, that mediate this sorting, and provide evidence that these actin-stabilized domains provide the physical basis for a two-step kinetic and affinity-based model for protein sorting into the sequence-dependent recycling pathway.
Multilevel Sequential${}^2$ Monte Carlo for Bayesian Inverse Problems
Creators: name: Latz, Jonas
name: Papaioannou, Iason
name: Ullmann, Elisabeth
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computation (stat.CO)
subject: FOS: Computer and information sciences
subject: 35R60, 62F15, 65C05, 65C35, 65N21, 65N30

description: The identification of parameters in mathematical models using noisy observations is a common task in uncertainty quantification. We employ the framework of Bayesian inversion: we combine monitoring and observational data with prior information to estimate the posterior distribution of a parameter. Specifically, we are interested in the distribution of a diffusion coefficient of an elliptic PDE. In this setting, the sample space is high-dimensional, and each sample of the PDE solution is expensive. To address these issues we propose and analyse a novel Sequential Monte Carlo (SMC) sampler for the approximation of the posterior distribution. Classical, single-level SMC constructs a sequence of measures, starting with the prior distribution, and finishing with the posterior distribution. The intermediate measures arise from a tempering of the likelihood, or, equivalently, a rescaling of the noise. The resolution of the PDE discretisation is fixed. In contrast, our estimator employs a hierarchy of PDE discretisations to decrease the computational cost. We construct a sequence of intermediate measures by decreasing the temperature or by increasing the discretisation level at the same time. This idea builds on and generalises the multi-resolution sampler proposed in [P.S. Koutsourelakis, J. Comput. Phys., 228 (2009), pp. 6184-6211] where a bridging scheme is used to transfer samples from coarse to fine discretisation levels. Importantly, our choice between tempering and bridging is fully adaptive. We present numerical experiments in 2D space, comparing our estimator to single-level SMC and the multi-resolution sampler.
FLAG Review 2019
Creators: name: Aoki, S.
name: Aoki, Y.
name: Becirevic, D.
name: Blum, T.
name: Colangelo, G.
name: Collins, S.
name: Della Morte, M.
name: Dimopoulos, P.
name: Dürr, S.
name: Fukaya, H.
name: Golterman, M.
name: Gottlieb, Steven
name: Gupta, R.
name: Hashimoto, S.
name: Heller, U. M.
name: Herdoiza, G.
name: Horsley, R.
name: Jüttner, A.
name: Kaneko, T.
name: Lin, C. -J. D.
name: Lunghi, E.
name: Mawhinney, R.
name: Nicholson, A.
name: Onogi, T.
name: Pena, C.
name: Portelli, A.
name: Ramos, A.
name: Sharpe, S. R.
name: Simone, J. N.
name: Simula, S.
name: Sommer, R.
name: Van De Water, R.
name: Vladikas, A.
name: Wenger, U.
name: Wittig, H.
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2019

description: We review lattice results related to pion, kaon, $D$-meson, $B$-meson, and nucleon physics with the aim of making them easily accessible to the nuclear and particle physics communities. More specifically, we report on the determination of the light-quark masses, the form factor $f_+(0)$ arising in the semileptonic $K \to \pi$ transition at zero momentum transfer, as well as the decay constant ratio $f_K/f_\pi$ and its consequences for the CKM matrix elements $V_{us}$ and $V_{ud}$. Furthermore, we describe the results obtained on the lattice for some of the low-energy constants of $SU(2)_L\times SU(2)_R$ and $SU(3)_L\times SU(3)_R$ Chiral Perturbation Theory. We review the determination of the $B_K$ parameter of neutral kaon mixing as well as the additional four $B$ parameters that arise in theories of physics beyond the Standard Model. For the heavy-quark sector, we provide results for $m_c$ and $m_b$ as well as those for $D$- and $B$-meson decay constants, form factors, and mixing parameters. These are the heavy-quark quantities most relevant for the determination of CKM matrix elements and the global CKM unitarity-triangle fit. We review the status of lattice determinations of the strong coupling constant $\alpha_s$. Finally, in this review we have added a new section reviewing results for nucleon matrix elements of the axial, scalar and tensor bilinears, both isovector and flavor diagonal.
A Characteristic Number of Hamiltonian Bundles over $S^2$
Creators: name: Viña, Andrés
Publisher: name: arXiv
Year: 2005
Subjects: subject: Symplectic Geometry (math.SG)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53D05; 57S05

description: Each loop $ψ$ in the group $\text{Ham}(M)$ of Hamiltonian diffeomorphisms of a symplectic manifold $M$ determines a fibration $E$ on $S^2$, whose coupling class \cite{G-L-S} is denoted by $c$. If $VTE$ is the vertical tangent bundle of $E$, we relate the characteristic number $\int_E c_1(VTE)c^n$ with the Maslov index of the linearized flow $ψ_{t*}$ and the Chern class $c_1(TM)$. We give the value of this characteristic number for loops of Hamiltonian symplectomorphisms of Hirzebruch surfaces.
description: Version to appear in Journal of Geometry and Physics
Estimation of Polarized Power Spectra by Gibbs sampling
Creators: name: Larson, D. L.
name: Eriksen, H. K.
name: Wandelt, B. D.
name: Gorski, K. M.
name: Huey, Greg
name: Jewell, J. B.
name: O'Dwyer, I. J.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Earlier papers introduced a method of accurately estimating the angular cosmic microwave background (CMB) temperature power spectrum based on Gibbs sampling. Here we extend this framework to polarized data. All advantages of the Gibbs sampler still apply, and exact analysis of mega-pixel polarized data sets is thus feasible. These advantages may be even more important for polarization measurements than for temperature measurements. While approximate methods can alias power from the larger E-mode spectrum into the weaker B-mode spectrum, the Gibbs sampler (or equivalently, exact likelihood evaluations) allows for a statistically optimal separation of these modes in terms of power spectra. To demonstrate the method, we analyze two simulated data sets: 1) a hypothetical future CMBPol mission, with the focus on B-mode estimation; and 2) a Planck-like mission, to highlight the computational feasibility of the method.
description: 8 pages, 5 figures. High-resolution version available from http://www.astro.uio.no/~hke/docs/larson_et_al_2006.ps.gz; accepted for publication in ApJ
Deep Air Learning: Interpolation, Prediction, and Feature Analysis of Fine-grained Air Quality
Creators: name: Qi, Zhongang
name: Wang, Tianchun
name: Song, Guojie
name: Hu, Weisong
name: Li, Xi
name: Zhongfei
name: Zhang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: The interpolation, prediction, and feature analysis of fine-gained air quality are three important topics in the area of urban air computing. The solutions to these topics can provide extremely useful information to support air pollution control, and consequently generate great societal and technical impacts. Most of the existing work solves the three problems separately by different models. In this paper, we propose a general and effective approach to solve the three problems in one model called the Deep Air Learning (DAL). The main idea of DAL lies in embedding feature selection and semi-supervised learning in different layers of the deep learning network. The proposed approach utilizes the information pertaining to the unlabeled spatio-temporal data to improve the performance of the interpolation and the prediction, and performs feature selection and association analysis to reveal the main relevant features to the variation of the air quality. We evaluate our approach with extensive experiments based on real data sources obtained in Beijing, China. Experiments show that DAL is superior to the peer models from the recent literature when solving the topics of interpolation, prediction, and feature analysis of fine-gained air quality.
Nature-Inspired Devices from Plasmonic Nanomaterials
Creators: name: Huang, Yifeng
Publisher: name: Monash University
Year: 2025
Subjects: classificationCode: 400499
subject: Chemical engineering not elsewhere classified

description: Nature is a precious source of inspiration because of the innumerable well-engineered structures and processes evolved in millions of years. Nature-inspired devices mimic the structures and functions of creatures for higher efficiency. Inspired by natural leaves, this thesis develops artificial leaves for catalysing several reactions actuated by light.
Sequence similarity network reveals common ancestry of multidomain proteins.
Creators: name: Song, Nan
name: Joseph, Jacob M.
name: Davis, George B.
name: Durand, Dannie
Publisher: name: Carnegie Mellon University
Year: 2008
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: We address the problem of homology identification in complex multidomain families with varied domain architectures. The challenge is to distinguish sequence pairs that share common ancestry from pairs that share an inserted domain but are otherwise unrelated. This distinction is essential for accuracy in gene annotation, function prediction, and comparative genomics. There are two major obstacles to multidomain homology identification: lack of a formal definition and lack of curated benchmarks for evaluating the performance of new methods. We offer preliminary solutions to both problems: 1) an extension of the traditional model of homology to include domain insertions; and 2) a manually curated benchmark of well-studied families in mouse and human. We further present Neighborhood Correlation, a novel method that exploits the local structure of the sequence similarity network to identify homologs with great accuracy based on the observation that gene duplication and domain shuffling leave distinct patterns in the sequence similarity network. In a rigorous, empirical comparison using our curated data, Neighborhood Correlation outperforms sequence similarity, alignment length, and domain architecture comparison. Neighborhood Correlation is well suited for automated, genome-scale analyses. It is easy to compute, does not require explicit knowledge of domain architecture, and classifies both single and multidomain homologs with high accuracy. Homolog predictions obtained with our method, as well as our manually curated benchmark and a web-based visualization tool for exploratory analysis of the network neighborhood structure, are available at http://www.neighborhoodcorrelation.org. Our work represents a departure from the prevailing view that the concept of homology cannot be applied to genes that have undergone domain shuffling. In contrast to current approaches that either focus on the homology of individual domains or consider only families with identical domain architectures, we show that homology can be rationally defined for multidomain families with diverse architectures by considering the genomic context of the genes that encode them. Our study demonstrates the utility of mining network structure for evolutionary information, suggesting this is a fertile approach for investigating evolutionary processes in the post-genomic era.
Promoting lentil germination and stem growth by plasma activated tap water, demineralized water and liquid fertilizer
Creators: name: Zhang, S.
name: Rousseau, A.
name: Dufour, T.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Other Quantitative Biology (q-bio.OT)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Tap water, demineralized water and liquid fertilizer have been activated using an atmospheric pressure plasma jet (APPJ) to investigate their benefits for the germination rate and stem elongation rate of lentils from Puy-en-Velay (France). By plasma-activating tap water, we have obtained germination rates as high as 80% (instead of 30% with tap water). Also, higher stem elongation rates and final stem lengths were obtained using activated tap water compared with commercial fertilizer. We show that these rates of germination and stem growth strongly depend on the combination of two radicals generated in the liquids by the plasma: hydrogen peroxide and nitrate. This synergy appears to be a condition for releasing seed dormancy through the endogenous production of NO radicals.
description: 8 pages, 9 figures, article with peer review
Additional file 1 of Network visualization of genes involved in skeletal muscle myogenesis in livestock animals
Creators: name: Nejad, Fatemeh Mohammadi
name: Mohammadabadi, Mohammadreza
name: Roudbari, Zahra
name: Gorji, Abdolvahab Ebrahimpour
name: Sadkowski, Tomasz
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 1
Hadronic processes and electromagnetic corrections
Creators: name: Scimemi, Ignazio
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The inclusion of electromagnetism in a low energy effective theory is worth further study in view of the present high precision experiments (muon g-2, pi_0->2 gamma, tau decays, etc.). In particular in many applications of chiral perturbation theory, one has to purify physical matrix elements from electromagnetic effects. The theoretical problems that I want to point out here are following: the splitting of a pure QCD and a pure electromagnetic part in a hadronic process is model dependent: is it possible to parametrise in a clear way this splitting? What kind of information (scale dependence, gauge dependence,..) is actually included in the parameters of the low energy effective theory? I will attempt to answer these questions introducing a possible convention to perform the splitting between strong and electromagnetic parts in some examples.
description: 6 latex pages, Talk given at SIGHAD2003, Pisa (Italy), October 8-10, 2003
Additional file 1 of Quantitative evaluation of disease severity in connective tissue disease-associated interstitial lung disease by dual-energy computed tomography
Creators: name: Chen, Ling
name: Zhu, Min
name: Lu, Haiyan
name: Yang, Ting
name: Li, Wanjiang
name: Zhang, Yali
name: Xie, Qibing
name: Li, Zhenlin
name: Wan, Huajing
name: Luo, Fengming
Publisher: name: figshare
Year: 2022
Subjects: Biochemistry
Medicine
Cell Biology
Molecular Biology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: Additional file 1: Table S1. Comparison the DECT parameters among TEI>20% and TEI≤20%.Table S2. Comparison DECT parameters among Group mild (FVC%≥80% & DLCO%≥80%), Group moderate (the indeterminate) and Group severe (FVC%≤50% or DLCO%≤50%). Table S3. Comparison demographic characteristics, volume, Zeff value and monochromatic CTN between limited CTD-ILD/extensive CTD-ILD group and the control group. Table S4. Pearson/Spearman correlation coefficient Matrix of DECT parameters with SF-36, TEI and PFT findings. Table S5. Receiver operating characteristic curve to demonstrate optimal cutoff value of DECT parameters to detect presence of extensive disease of CTD-ILD. Table S6. Comparison the DECT parameters among different degree of dyspnea according to Borg dyspnea score. Table S7. Comparison the DECT parameters among different severity cough symptom according to LCQ with the cut-off value 17. Table S8. Linear Regression Analysis to Define the Variables Contribution to PCS in patient with CTD-ILD. Table S9. Linear Regression Analysis to Define the Variables Contribution to MCS in patient with CTD-ILD. Table S10. Binary Logistic Regression Analysis of Univariate Analysis and Multivariate Analysis with Dyspnea of CTD-ILD patient. Table S11. Binary Logistic Regression Analysis of Univariate Analysis and Multivariate Analysis with Cough of CTD-ILD patient.
Sentinel lymph node imaging using quantum dots in mouse tumor models.
Creators: name: Ballou, Byron
name: Ernst, Lauren A.
name: Andreko, Susan
name: Harper, Theresa
name: Fitzpatrick, James
name: Waggoner, Alan
name: Bruchez, Marcel
Publisher: name: Carnegie Mellon University
Year: 2007
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: We demonstrate that quantum dots injected into two model tumors rapidly migrate to sentinel lymph nodes. PEG-coated quantum dots having terminal carboxyl, amino, or methoxyl groups all migrated from the tumor to surrounding lymph nodes similarly. Passage from the tumor through lymphatics to adjacent nodes could be visualized dynamically through the skin; at least two nodes could usually be defined. Imaging during necropsy confirmed confinement of the quantum dots to the lymphatic system and demonstrated easy tagging of sentinel lymph nodes for pathology. Examination of the sentinel nodes identified by quantum dot localization showed that at least some contained metastatic tumor foci.
Max-plus definite matrix closures and their eigenspaces
Creators: name: Sergeev, Sergei
Publisher: name: arXiv
Year: 2005
Subjects: subject: Metric Geometry (math.MG)
subject: FOS: Mathematics
subject: 15A18, 52A99

description: In this paper we introduce the definite closure operation for max-plus matrices with finite permanent, reveal inner structures of definite eigenspaces, and establish some facts about Hilbert distances between these inner structures and the boundary of the definite eigenspace
description: 20 pages,6 figures, v2: minor changes in figures and in the main text
Inferring Compton-thick AGN candidates at z>2 with Chandra using the >8 keV restframe spectral curvature
Creators: name: Baronchelli, L.
name: Koss, M.
name: Schawinski, K.
name: Cardamone, C.
name: Civano, F.
name: Comastri, A.
name: Elvis, M.
name: Lanzuisi, G.
name: Marchesi, S.
name: Ricci, C.
name: Salvato, M.
name: Trakhtenbrot, B.
name: Treister, E.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: To fully understand cosmic black hole growth we need to constrain the population of heavily obscured active galactic nuclei (AGN) at the peak of cosmic black hole growth ($z\sim$1-3). Sources with obscuring column densities higher than $\mathrm{10^{24}}$ atoms $\mathrm{cm^{-2}}$, called Compton-thick (CT) AGN, can be identified by excess X-ray emission at $\sim$20-30 keV, called the "Compton hump". We apply the recently developed Spectral Curvature (SC) method to high-redshift AGN (25\times 10^{43}}$ erg $\mathrm{s^{-1}}$. In the Cosmological evolution survey (COSMOS), we find an observed CT fraction of $\mathrm{15^{+4}_{-3}\%}$ (40/272) or $\mathrm{32\pm11 \%}$ when corrected for the survey sensitivity. When comparing to low redshift AGN with similar X-ray luminosities, our results imply the CT AGN fraction is consistent with having no redshift evolution. Finally, we provide SC equations that can be used to find high-redshift CT AGN (z>1) for current (XMM-Newton) and future (eROSITA and ATHENA) X-ray missions.
description: 10 pages, 8 figures
Sensitive and automated detection of iron-oxide-labeled cells using phase image cross-correlation analysis.
Creators: name: Mills, Parker H.
name: Yi-Jen L. Wu
name: Ho, Chien
name: Ahrens, Eric T.
Publisher: name: Carnegie Mellon University
Year: 2008
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Superparamagnetic iron oxide (SPIO) nanoparticles are increasingly being used to noninvasively track cells, target specific molecules and monitor gene expression in vivo. Contrast changes that are subtle relative to intrinsic sources of contrast present a significant detection challenge. Here, we describe a postprocessing algorithm, called Phase map cross-correlation Detection and Quantification (PDQ), with the purpose of automating identification and quantification of localized accumulations of SPIO agents. The method is designed to sacrifice little flexibility - it works on previously acquired data and allows the use of conventional high-SNR pulse sequences with no extra scan time. We first investigated the theoretical detection limits of PDQ using a simulated dipole field. This method was then applied to three-dimensional (3D) MRI data sets of agarose gel containing isolated dipoles and ex vivo transplanted allogenic rat hearts infiltrated by numerous iron-oxide-labeled macrophages as a result of organ rejection. A simulated dipole field showed this method to be robust in very low signal-to-noise ratio images. Analysis of agarose gel and allogenic rat heart shows that this method can automatically identify and count dipoles while visualizing their biodistribution in 3D renderings. In the heart, this information was used to calculate a quantitative index that may indicate its degree of cellular infiltration.
title: ADCO, Ordre cistercien : comptes (1499-1515) (11 H 1162), f. 00211
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Ordre cistercien : comptes (1499-1515), Archives départementales de la Côte-d'Or, (11 H 1162). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1499-1515), Archives départementales de la Côte-d'Or, (11 H 1162), f. 00211, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
On-sky results of the adaptive optics MACAO for the new IR-spectrograph CRIRES at VLT
Creators: name: Paufique, J.
name: Biereichel, P.
name: Delabre, B.
name: Donaldson, R.
name: Esteves, R.
name: Fedrigo, E.
name: Gigan, P.
name: Gojak, D.
name: Hubin, N.
name: Kasper, M.
name: Kaeufl, U.
name: Lizon, JL.
name: Marchetti, E.
name: Oberti, S.
name: Pirard, JF.
name: Pozna, E.
name: Santos, J.
name: Stroebele, S.
name: Tordo, S.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The adaptive optics MACAO has been implemented in 6 focii of the VLT observatory, in three different flavors. We present in this paper the results obtained during the commissioning of the last of these units, MACAO-CRIRES. CRIRES is a high-resolution spectrograph, which efficiency will be improved by a factor two at least for point-sources observations with a NGS brighter than R=15. During the commissioning, Strehl exceeding 60% have been observed with fair seeing conditions, and a general description of the performance of this curvature adaptive optics system is done.
description: SPIE conference 2006, Advances in adaptive optics, 12 pages, 11 figures
Additional file 1 of Association between preoperative frailty and myocardial injury after noncardiac surgery in geriatric patients: study protocol for a prospective, multicentre, real-world observational, cohort trial
Creators: name: Sun, Yongtao
name: Guo, Na
name: Zhang, Min
name: Liu, Mengjie
name: Gao, Zhongquan
name: Sun, Tao
name: Gao, Xiaojun
name: Xu, Lingling
name: Zhang, Haixia
name: Wei, Chuansong
name: Liu, Peng
name: Liu, Yang
name: Zhang, Xiaoning
name: Guo, Yongle
name: Chen, Lina
name: Zhou, Zheng
name: Su, Zhenqiang
name: Hu, Yanmei
name: Shi, Xin
name: Huang, Linlin
name: Wang, Yuelan
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Lifting degeneracies in the oscillation parameters by a neutrino factory
Creators: name: Aoki, Mayumi
name: Hagiwara, Kaoru
name: Okamura, Naotoshi
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the potential of a very long baseline neutrino oscillation experiment with a neutrino factory and a large segmented water-Cerenkov calorimeter detector in resolving the degeneracies in the neutrino oscillation parameters; the sign of the larger mass-squared difference $δm^2_{13}$, the sign of $|U_{μ3}|^2 (\equiv \sin^2θ_{ATM)-1/2$, and a possible two-fold ambiguity in the determination of the CP phase $δ_{MNS}$. We find that the above problems can be resolved even if the particle charges are not measured. The following results are obtained in our exploratory study for a neutrino factory which delivers $10^{21}$ decaying $μ^+$ and $μ^-$ at 10 GeV and a 100 kton detector which is placed 2,100 km away and is capable of measuring the event energy and distinguishing $e^\pm$ from $μ^\pm$, but not their charges. The sign of $δm^2_{13}$ can be determined for $4|U_{e3}|^2(1-|U_{e3}|^2)\equiv \sin^22θ_{RCT}\gsim 0.008$. That of $\sin^2θ_{ATM}-1/2$ can be resolved for $\sin^22θ_{ATM}=0.96$ when $\sin^22θ_{RCT}\gsim 0.06$. The CP-violating phase $δ_{MNS}$ can be uniquely constrained for $\sin^22θ_{RCT}\gsim 0.02$ if its true value is around $90^\circ$ or $270^\circ$, while it can be constrained for $\sin^22θ_{RCT}\gsim 0.03$ if its true value is around $0^\circ$ or $180^\circ$.
description: 15 pages,6 figures, More discussions added together with some figures. References added
Leakage and sweet spots in triple-quantum-dot spin qubits: A molecular-orbital study
Creators: name: Zhang, Chengxian
name: Yang, Xu-Chen
name: Wang, Xin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A triple-quantum-dot system can be operated as either an exchange-only qubit or a resonant-exchange qubit. While it is generally believed that the decisive advantage of the resonant-exchange qubit is the suppression of charge noise because it is operated at a sweet spot, we show that the leakage is also an important factor. Through molecular-orbital-theoretic calculations, we show that when the system is operated in the exchange-only scheme, the leakage to states with double electron occupancy in quantum dots is severe when rotations around the axis 120$^\circ$ from $\hat{z}$ is performed. While this leakage can be reduced by either shrinking the dots or separating them further, the exchange interactions are also suppressed at the same time, making the gate operations unfavorably slow. When the system is operated as a resonant-exchange qubit, the leakage is 3-5 orders of magnitude smaller. We have also calculated the optimal detuning point which minimizes the leakage for the resonant-exchange qubit, and have found that although it does not coincide with the double-sweet-spot for the charge noise, they are rather close. Our results suggest that the resonant-exchange qubit has another advantage that leakage can be greatly suppressed compared to the exchange-only qubit, and operating at the double-sweet-spot point should be optimal both for reducing charge noise and suppressing leakage.
description: 11 pages, 14 figures
Ligustrum vulgare Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Oleaceae
Ligustrum
Ligustrum vulgare

description: Ligustrum vulgare Linnaeus, Species Plantarum 1: 7. 1753.
"Habitat in Europae collibus glareosis." RCN: 49.
 Lectotype (Green in Jarvis & al., Regnum Veg. 127: 61. 1993): Herb. Linn. No. 18.1 (LINN).
 Generitype of Ligustrum Linnaeus.
 Current name: Ligustrum vulgare L. (Oleaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 632, DOI: 10.5281/zenodo.291971
Can one see the fundamental frequency of a drum?
Creators: name: Maz'ya, Vladimir
name: Shubin, Mikhail
Publisher: name: arXiv
Year: 2005
Subjects: subject: Spectral Theory (math.SP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 35P15

description: We establish two-sided estimates for the fundamental frequency (the lowest eigenvalue) of the Laplacian in an open subset G of R^n with the Dirichlet boundary condition. This is done in terms of the interior capacitary radius of G which is defined as the maximal possible radius of a ball B which has a negligible intersection with the complement of G. Here negligibility of a subset F in B means that the Wiener capacity of F does not exceed gamma times the capacity of B, where gamma is an arbitrarily fixed constant between 0 and 1. We provide explicit values of constants in the two-sided estimates.
description: 18 pages, some misprints corrected
Self-Checking Cell-Based Assays for GPCR Desensitization and Resensitization.
Creators: name: Fisher, Gregory
name: Fuhrman, Margaret H.
name: Adler, Sally A.
name: Szent-Gyorgyi, Christopher
name: Waggoner, Alan
name: Jarvik, Jonathan
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: G protein-coupled receptors (GPCRs) play stimulatory or modulatory roles in numerous physiological states and processes, including growth and development, vision, taste and olfaction, behavior and learning, emotion and mood, inflammation, and autonomic functions such as blood pressure, heart rate, and digestion. GPCRs constitute the largest protein superfamily in the human and are the largest target class for prescription drugs, yet most are poorly characterized, and of the more than 350 nonolfactory human GPCRs, over 100 are orphans for which no endogenous ligand has yet been convincingly identified. We here describe new live-cell assays that use recombinant GPCRs to quantify two general features of GPCR cell biology-receptor desensitization and resensitization. The assays employ a fluorogen-activating protein (FAP) reporter that reversibly complexes with either of two soluble organic molecules (fluorogens) whose fluorescence is strongly enhanced when complexed with the FAP. Both assays require no wash or cleanup steps and are readily performed in microwell plates, making them adaptable to high-throughput drug discovery applications.
Additional file 1 of Coagulation dysfunction events associated with tigecycline: a real-world study from FDA adverse event reporting system (FAERS) database
Creators: name: Guo, Mingxing
name: Liang, Jinwei
name: Li, Dandan
name: Zhao, Ying
name: Xu, Wanyi
name: Wang, Lei
name: Cui, Xiangli
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Additional file 1: Appendix Table 1. Search terms for tigecycline and its control drugs.
title: ADCO, Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Cart. 172 (11 H 69), 115 folios, f. 0092
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi

description: Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Archives départementales de la Côte-d'Or, Cart. 172 (11 H 69), 115 folios, f. 0092, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Archives départementales de la Côte-d'Or, Cart. 172 (11 H 69), 115 folios, f. 0092, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
CGCG 480-022: A distant lonesome merger?
Creators: name: Carretero, C.
name: Vazdekis, A.
name: Gonzalez-Garcia, C.
name: Beckman, J. E.
name: Quilis, V.
name: ;
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a complete analysis, which includes morphology, kinematics, stellar populations and N-body simulations of CGCG 480-022, the most distant (cz=14317 km/s) isolated galaxy studied so far in such detail. The results all support the hypothesis that this galaxy has suffered a major merger event with a companion of ~0.1 times its mass. Morphology reveals the presence of a circumnuclear ring and possibly further ring debris. The radial velocity curve looks symmetrical, whilst the velocity dispersion increases with radius reaching values that do not correspond to a virialized system. Moreover, this galaxy deviates significantly from the Fundamental Plane and the Faber-Jackson relation. The stellar population analysis show that the ring is younger and more metal-rich, which suggest that it has undergone a fairly recent burst of star formation. Both morphological and dynamical results are in broad agreeement with our N-body simulations.
description: Accepted for publication in ApJ Letters
The sustainable growth of the first black holes
Creators: name: Pezzulli, Edwige
name: Volonteri, Marta
name: Schneider, Raffaella
name: Valiante, Rosa
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Super-Eddington accretion has been suggested as a possible formation pathway of $10^9 \, M_\odot$ supermassive black holes (SMBHs) 800 Myr after the Big Bang. However, stellar feedback from BH seed progenitors and winds from BH accretion disks may decrease BH accretion rates. In this work, we study the impact of these physical processes on the formation of $z \sim 6$ quasar, including new physical prescriptions in the cosmological, data-constrained semi-analytic model GAMETE/QSOdust. We find that the feedback produced by the first stellar progenitors on the surrounding does not play a relevant role in preventing SMBHs formation. In order to grow the $z \gtrsim 6$ SMBHs, the accreted gas must efficiently lose angular momentum. Moreover disk winds, easily originated in super-Eddington accretion regime, can strongly reduce duty cycles. This produces a decrease in the active fraction among the progenitors of $z\sim6$ bright quasars, reducing the probability to observe them.
title: ADCO, Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Cart. 23 (G 127), 310 folios, f. 00112
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00112, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00112, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Self-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex.
Creators: name: Kunttas-Tatli, Ezgi
name: Roberts, David M.
name: McCartney, Brooke M.
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The tumor suppressor Adenomatous polyposis coli (APC) is an essential negative regulator of Wnt signaling through its activity in the destruction complex with Axin, GSK3β and CK1 that targets ß-catenin/Armadillo (ß-cat/Arm) for proteosomal degradation. The destruction complex forms macromolecular particles we termed the destructosome. While APC functions in the complex through its ability to bind both ß-cat and Axin, we hypothesize that APC proteins play an additional role in destructosome assembly through self-association. Here we show that a novel N-terminal coil, the APC Self-Association Domain (ASAD), found in vertebrate and invertebrate APCs, directly mediates self-association of Drosophila APC2 and plays an essential role in the assembly and stability of the destructosome that regulates ß-cat degradation in Drosophila and human cells. Consistent with this, removal of the ASAD from the Drosophila embryo results in ß-cat/Arm accumulation and aberrant Wnt pathway activation. These results suggest that APC proteins are required not only for the activity of the destructosome, but also for the assembly and stability of this macromolecular machine.
Fundamental work cost of quantum processes
Creators: name: Faist, Philippe
name: Renner, Renato
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Information-theoretic approaches provide a promising avenue for extending the laws of thermodynamics to the nanoscale. Here, we provide a general fundamental lower limit, valid for systems with an arbitrary Hamiltonian and in contact with any thermodynamic bath, on the work cost for the implementation of any logical process. This limit is given by a new information measure---the coherent relative entropy---which accounts for the Gibbs weight of each microstate. The coherent relative entropy enjoys a collection of natural properties justifying its interpretation as a measure of information, and can be understood as a generalization of a quantum relative entropy difference. As an application, we show that the standard first and second laws of thermodynamics emerge from our microscopic picture in the macroscopic limit. Finally, our results have an impact on understanding the role of the observer in thermodynamics: Our approach may be applied at any level of knowledge---for instance at the microscopic, mesoscopic or macroscopic scales---thus providing a formulation of thermodynamics that is inherently relative to the observer. We obtain a precise criterion for when the laws of thermodynamics can be applied, thus making a step forward in determining the exact extent of the universality of thermodynamics and enabling a systematic treatment of Maxwell-demon-like situations.
description: Journal version, 13+24 pages. The present results have been reported to a large extent in PhF's Ph.D. thesis (arXiv:1607.03104)
Additional file 2 of Coagulation dysfunction events associated with tigecycline: a real-world study from FDA adverse event reporting system (FAERS) database
Creators: name: Guo, Mingxing
name: Liang, Jinwei
name: Li, Dandan
name: Zhao, Ying
name: Xu, Wanyi
name: Wang, Lei
name: Cui, Xiangli
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Additional file 2: Appendix Table 2. Search terms for adverse events related to coagulation dysfunction.
A combinatorial Yamabe flow in three dimensions
Creators: name: Glickenstein, David
Publisher: name: arXiv
Year: 2005
Subjects: subject: Metric Geometry (math.MG)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 52C26

description: A combinatorial version of Yamabe flow is presented based on Euclidean triangulations coming from sphere packings. The evolution of curvature is then derived and shown to satisfy a heat equation. The Laplacian in the heat equation is shown to be a geometric analogue of the Laplacian of Riemannian geometry, although the maximum principle need not hold. It is then shown that if the flow is nonsingular, the flow converges to a constant curvature metric.
description: 20 pages, 5 figures. The paper arxiv:math.MG/0211195 was absorbed into its new version and this paper
Direct micro-patterning of biodegradable polymers using ultraviolet and femtosecond lasers
Creators: name: Aguilar, Carlos Andres
Publisher: name: The University of Texas at Austin
Year: 2005
Subjects: Biodegradable polymer
Laser micromachining
Femtosecond laser
Excimer laser

description: Biodegradable polymeric materials have had a significant impact on medical technology, greatly enhancing the efficacy of many existing drugs and enabling the construction of entirely new therapeutic modalities. The development of next-generation micro and nano medical devices using biodegradable polymers relies heavily on advanced fabrication techniques. We present a general fabrication process involving the use of ultraviolet and femtosecond lasers for micro-machining the biodegradable polymers, poly ([epsilon]- caprolactone) (PCL) and Poly (glycolic acid) (PGA). The surface profile and morphology of the polymers were studied after laser direct patterning using a scanning electron microscope (SEM), surface profilometer, X-ray photoelectron spectroscopy (XPS) and Fourier Transform InfraRed Spectroscopy in Attenuated Total Reflectance mode (FTIR-ATR). The influence of the laser effects on the degradation characteristics of the biodegradable polymers are also reported and verified through In-vitro degradation tests after laser ablation. Our results demonstrate a rapid, flexible, reproducible and chemical-free approach for generating high-resolution micro-patterns on biodegradable polymers
Additional file 1 of ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells
Creators: name: Lin, Ting
name: Zhang, Shuxian
name: Tang, Yi
name: Xiao, Ming
name: Li, Ming
name: Gong, Hanjuan
name: Xie, Hailun
name: Wang, Yalan
Publisher: name: figshare
Year: 2024
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Supplementary Material 1
Attenuation modified by DIG and dust as seen in M31
Creators: name: Tomicic, Neven
name: Kreckel, Kathryn
name: Groves, Brent
name: Schinnerer, Eva
name: Sandstrom, Karin
name: Kapala, Maria
name: Blanc, Guillermo A.
name: Leroy, Adam
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The spatial distribution of dust in galaxies affects the global attenuation, and hence inferred properties, of galaxies. We trace the spatial distribution of dust in five fields (at 0.6-0.9 kpc scale) of M31 by comparing optical attenuation with the total dust mass distribution. We measure the attenuation from the Balmer decrement using Integral Field Spectroscopy and the dust mass from Herschel far-IR observations. Our results show that M31's dust attenuation closely follows a foreground screen model, contrary to what was previously found in other nearby galaxies. By smoothing the M31 data we find that spatial resolution is not the cause for this difference. Based on the emission line ratios and two simple models, we conclude that previous models of dust/gas geometry need to include a weakly or non-attenuated diffuse ionized gas (DIG) component. Due to the variation of dust and DIG scale heights with galactic radius, we conclude that different locations in galaxies will have different vertical distributions of gas and dust and therefore different measured attenuation. The difference between our result in M31 with that found in other nearby galaxies can be explained by our fields in M31 lying at larger galactic radii than the previous studies that focused on the centres of galaxies.
description: 20 pages, 13 figures, ApJ accepted and in press