Additional file 1 of Regional venous–arterial CO2 to arterial–venous O2 content difference ratio in experimental circulatory shock and hypoxia
Creators: name: Corrêa, Thiago Domingos
name: Pereira, Adriano José
name: Takala, Jukka
name: Jakob, Stephan Mathias
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: FOS: Clinical medicine
subject: Cancer
subject: Computational Biology

description: Additional file 1 (DOCX 750 kb) Table S1. Survival accordingly to study groups. Values represent n/n total (%).Table S2. Correlation between renal venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) and systemic and regional hemodynamics, kidney vein hemoglobin and blood gas analysis, and lactate uptake (n = 313). Table S3. Correlation between spleen venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) and systemic and regional hemodynamics, spleen vein hemoglobin and blood gas analysis, and lactate uptake (n = 294). Table S4. Correlation between gut venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) and systemic and regional hemodynamics, mesenteric vein hemoglobin and blood gas analysis, and lactate uptake (n = 312). Table S5. Correlations between liver venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) and systemic and regional hemodynamics, liver vein hemoglobin and blood gas analysis, and lactate uptake (n = 313). Table S6. Correlation between renal venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) and systemic and regional hemodynamics, kidney vein hemoglobin and blood gas analysis, and lactate uptake (n = 170; including only systemic Cv-aCO2/Ca-vO2 &gt; 1.0). Table S7. Correlation between spleen venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) and systemic and regional hemodynamics, spleen vein hemoglobin and blood gas analysis, and lactate uptake (n = 162; including only systemic Cv-aCO2/Ca-vO2 &gt; 1.0). Table S8. Correlation between gut venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) and systemic and regional hemodynamics, mesenteric vein hemoglobin and blood gas analysis, and lactate uptake (n = 166; including only systemic Cv-aCO2/Ca-vO2 &gt; 1.0). Table S9. Correlations between liver venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) and systemic and regional hemodynamics, liver vein hemoglobin and blood gas analysis, and lactate uptake (n=171; including only systemic Cv-aCO2/Ca-vO2 &gt; 1.0). Table S10. Contributors to systemic venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) (n = 147; including only systemic Cv-aCO2/Ca-vO2 &gt; 1.0). Table S11. Contributors to systemic venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) after adjusting for experimental group (n = 255). Table S12. Contributors to systemic venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) after adjusting for experimental group (n = 147; including only systemic Cv-aCO2/Ca-vO2 &gt; 1.0). Figure S1. Linear regression and correlation between arterial lactate and base excess. Figure S2. Boxplot of pooled hepatic, hepatosplanchnic, renal, mesenteric and spleen venous-arterial CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2). Figure S3. Systemic and regional CO2 to arterial-venous O2 content difference ratio (Cv-aCO2/Ca-vO2) accordingly to experimental models.