cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity
Creators: name: Bywater, Megan J.
name: Burkhart, Deborah L.
name: Straube, Jasmin
name: Sabò, Arianna
name: Pendino, Vera
name: Hudson, James E.
name: Quaife-Ryan, Gregory A.
name: Porrello, Enzo R.
name: Rae, James
name: Parton, Robert G.
name: Kress, Theresia R.
name: Amati, Bruno
name: Littlewood, Trevor D.
name: Evan, Gerard I.
name: Wilson, Catherine H.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/67/70
/631/80/641
/631/337/572
/64/60
/38/91
/13/1
/13/31
/13/51
/13/106
/14/28
/14/63
/38/23
/45/15
article

description: Abstract: It is unclear why some tissues are refractory to the mitogenic effects of the oncogene Myc. Here we show that Myc activation induces rapid transcriptional responses followed by proliferation in some, but not all, organs. Despite such disparities in proliferative response, Myc is bound to DNA at open elements in responsive (liver) and non-responsive (heart) tissues, but fails to induce a robust transcriptional and proliferative response in the heart. Using heart as an exemplar of a non-responsive tissue, we show that Myc-driven transcription is re-engaged in mature cardiomyocytes by elevating levels of the positive transcription elongation factor (P-TEFb), instating a large proliferative response. Hence, P-TEFb activity is a key limiting determinant of whether the heart is permissive for Myc transcriptional activation. These data provide a greater understanding of how Myc transcriptional activity is determined and indicate modification of P-TEFb levels could be utilised to drive regeneration of adult cardiomyocytes for the treatment of heart myopathies.
Budget impact analysis of betrixaban for venous thromboembolism prophylaxis in nonsurgical patients with acute medical illness in the United Kingdom
Creators: name: Guy, Holly
name: Laskier, Vicki
name: Fisher, Mark
name: Bucior, Iwona
name: Deitelzweig, Steven
name: Cohen, Alexander T.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Science Policy

description: Objectives: Venous thromboembolism (VTE) incurs substantial costs to the UK National Health Service (NHS). Betrixaban is approved in the US for VTE prophylaxis with a recommended 35–42 days of treatment. This analysis modeled the budget impact of introducing betrixaban for extended-duration VTE prophylaxis in nonsurgical patients with acute medical illness at risk of VTE in the UK, where it is not yet licensed. Methods: The 5-year budget impact of introducing betrixaban into current prophylaxis (low molecular weight heparin and fondaparinux) was estimated for the UK NHS. The Phase 3 APEX study provided primary event (VTE, myocardial infarction, ischemic stroke, and death; all-cause or VTE-related) and treatment complications data. Literature informed risk of recurrent events and long-term complications, population, market share, and costs for treatment and management of events. Network meta-analyses informed symptomatic DVT, pulmonary embolism and VTE-related death rates in fondaparinux patients. Deterministic sensitivity analyses explored uncertainty. Results: Introducing betrixaban accrued savings of £1,290,000-£23,000,000 in years 1–5. Savings were from reduced primary VTE events, which reduced recurrent events and future complications. All sensitivity analyses showed savings. Conclusion: Introducing extended-duration VTE prophylaxis with betrixaban in the UK would accrue substantial savings annually over the next 5 years compared to current prophylaxis. Clinical trial registration: www.clinicaltrials.gov identifier is NCT01583218.
Spin dynamics investigations for the EDM experiment at COSY
Creators: name: Rathmann, F.
name: Nikolaev, N. N.
name: Slim, J.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: Precision experiments, such as the search for a deuteron electric dipole moments using a storage rings like COSY, demand for an understanding of the spin dynamics with unprecedented accuracy. In such an enterprise, numerical predictions play a crucial role for the development and later application of spin-tracking algorithms. Various measurement concepts involving polarization effects induced by an RF Wien filter and static solenoids in COSY are discussed. The matrix formalism, applied here, deals \textit{solely} with spin rotations \textit{on the closed orbit} of the machine, and is intended to provide \textit{numerical} guidance for the development of beam and spin-tracking codes for rings that employ realistic descriptions of the electric and magnetic bending and focusing elements, solenoids etc., and a realistically-modeled RF Wien filter.
description: 25 pages, 21 figures, 6 tables
LP-LM: No Hallucinations in Question Answering with Logic Programming
Creators: name: Wu, Katherine
name: Liu, Yanhong A.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Large language models (LLMs) are able to generate human-like responses to user queries. However, LLMs exhibit inherent limitations, especially because they hallucinate. This paper introduces LP-LM, a system that grounds answers to questions in known facts contained in a knowledge base (KB), facilitated through semantic parsing in Prolog, and always produces answers that are reliable.
 LP-LM generates a most probable constituency parse tree along with a corresponding Prolog term for an input question via Prolog definite clause grammar (DCG) parsing. The term is then executed against a KB of natural language sentences also represented as Prolog terms for question answering. By leveraging DCG and tabling, LP-LM runs in linear time in the size of input sentences for sufficiently many grammar rules. Performing experiments comparing LP-LM with current well-known LLMs in accuracy, we show that LLMs hallucinate on even simple questions, unlike LP-LM.
description: In Proceedings ICLP 2024, arXiv:2502.08453
Maps of quantitative and qualitative data for each of the showcase locations - Synthesis report
Creators: name: Borges, Luciane Aguiar
name: Randall, Linda
name: Shinan Wang
Publisher: name: Zenodo
Year: 2021

description: This report presents a synthesis of the maps of quantitative and qualitative data for each of the SiEUGreen showcase locations and outlines a preliminary data collection strategy for the remainder of the SiEUGreen project. It is based on the reports provided by the case study expert for each showcase (Annex 1, 2, 3, 4 & 5), considered in the context of contemporary thinking about urban agriculture (UA) in developed countries. The report is presented in three parts: • Part 1 provides an overview of the European and Chinese showcases and outlines the methodology used. • Part 2 is the most substantial component and focuses on the four central concepts of the SiEUGreen project - land use, food security, resource efficiency and societal inclusion. It synthesizes data from the case study reports, incorporating academic literature as relevant. Comparative national-level data is also presented for food security and resource efficiency. The analysis is structured around the expected impacts set out in the project proposal, as relevant to each pillar. • Part 3 provides a concise summary of the findings from the maps of quantitative and qualitative data for each of the showcase locations before laying out a preliminary data collection strategy to inform the work undertaken in WP1 for the remainder of the SiEUGreen project.
Maximal entropy measures of diffeomorphisms of circle fiber bundles
Creators: name: Ures, Raúl
name: Viana, Marcelo
name: Yang, Jiagang
Publisher: name: arXiv
Year: 2019
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: We characterize the maximal entropy measures of partially hyperbolic C^2 diffeomorphisms whose center foliations form circle bundles, by means of suitable finite sets of saddle points, that we call skeletons. In the special case of 3-dimensional nilmanifolds other than the torus, this entails the following dichotomy: either the diffeomorphism is a rotation extension of an Anosov diffeomorphism -- in which case there is a unique maximal measure, with full support and zero center Lyapunov exponents -- or there exist exactly two ergodic maximal measures, both hyperbolic and whose center Lyapunov exponents have opposite signs. Moreover, the set of maximal measures varies continuously with the diffeomorphism.
Floquet Engineering with Particle Swarm Optimization: Maximizing Topological Invariants
Creators: name: Zhang, Shikun
name: Gong, Jiangbin
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: It is of theoretical and experimental interest to engineer topological phases with very large topological invariants via periodic driving. As advocated by this work, such Floquet engineering can be elegantly achieved by the particle swarm optimization (PSO) technique from the swarm intelligence family. With the recognition that conventional gradient-based optimization approaches are not suitable for directly optimizing topological invariants as integers, the highly effective PSO route yields new promises in the search for exotic topological phases, requiring limited physical resource. Our results are especially timely in view of two important insights from literature: low-frequency driving may be beneficial in creating large topological invariants, but an open-ended low-frequency driving often leads to drastic fluctuations in the obtained topological invariants. Indeed, using a simple continuously driven Harper model with three quasi-energy bands, we show that the Floquet-band Chern numbers can enjoy many-fold increase compared with that using a simple harmonic driving of the same period, without demanding more energy cost of the driving field. It is also found that the resulting Floquet insulator bands are still well-gapped, with the maximized topological invariants in agreement with physical observations from Thouless pumping. The emergence of many edge modes under the open boundary condition is also consistent with the bulk-edge correspondence. Our results are expected to be highly useful towards the optimization of many different types of topological invariants in Floquet topological matter.
description: 10 pages, 9 figures
Is the a_0(1450) a candidate for the lowest q\bar{q} ^3P_0 state?
Creators: name: Badalian, A. M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: For the $a_0(1450)$, considered as the $q\bar{q} 1^3P_0$ state, "experimental" tensor splitting, $c_{exp}=(-150\pm 40$) MeV, appears to be in contradiction with conventional theory of fine structure. There is no such discrepancy if the $a_0(980)$ belongs to the $1^3P_J q\bar{q}$ multiplet. The hadronic shift of the $a_0(980)$ is shown to be strongly dependent on the value of the strong coupling in spin-dependent interaction.
description: 13 pages
The efficacy and economic evaluation of roxadustat treatment for anemia in patients with kidney disease not receiving dialysis
Creators: name: Zhanhong Hu
name: Tao, Hong
name: Aiming Shi
name: Pan, Jie
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Science Policy

description: This study aimed to assess the efficacy, tolerance, and cost-effectiveness of roxadustat treatment for anemia in patients with chronic kidney disease not receiving dialysis (CKD ND). A meta-analysis was conducted to evaluate the clinical efficacy and tolerance of roxadustat for the correction of anemia associated with CKD ND, and a Markov model was developed to evaluate the cost-effectiveness of roxadustat compared with a placebo. The meta-analysis results showed that compared with a placebo, roxadustat treatment was associated with a remarkably higher rate of clinical response and the differences in the rate of adverse events between these two regimens were not significant. Moreover, roxadustat treatment (70 mg, three times per week) provided an additional 0.49 QALYs at a cost of $12,526 in the time horizon of 5 years, resulting in an ICER of $25,563 per QALY, with approximately 60% probability to be cost-effective at a $29,295 per QALY willingness-to-pay (WTP) threshold from the perspective of Chinese medical system. For the treatment of anemia in Chinese patients with CKD ND, roxadustat is much more effective than a placebo; moreover, it is cost-effective at conventional WTP thresholds.
Fluctuating Dimension in a Discrete Model for Quantum Gravity Based on the Spectral Principle
Creators: name: de Albuquerque, Luiz C.
name: deLyra, Jorge L.
name: Teotonio-Sobrinho, Paulo
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The spectral principle of Connes and Chamseddine is used as a starting point to define a discrete model for Euclidean quantum gravity. Instead of summing over ordinary geometries, we consider the sum over generalized geometries where topology, metric and dimension can fluctuate. The model describes the geometry of spaces with a countable number $n$ of points, and is related to the Gaussian unitary ensemble of Hermitian matrices. We show that this simple model has two phases. The expectation value $$, the average number of points in the universe, is finite in one phase and diverges in the other. We compute the critical point as well as the critical exponent of $$. Moreover, the space-time dimension $δ$ is a dynamical observable in our model, and plays the role of an order parameter. The computation of $$ is discussed and an upper bound is found, $ < 2$.
description: 10 pages, no figures. Third version: This new version emphasizes the spectral principle rather than the spectral action. Title has been changed accordingly. We also reformulated the computation of the dimension, and added a new reference. To appear in Physical Review Letters
Synchronization of random walks with reflecting boundaries
Creators: name: Ruttor, Andreas
name: Reents, Georg
name: Kinzel, Wolfgang
Publisher: name: arXiv
Year: 2004
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Reflecting boundary conditions cause two one-dimensional random walks to synchronize if a common direction is chosen in each step. The mean synchronization time and its standard deviation are calculated analytically. Both quantities are found to increase proportional to the square of the system size. Additionally, the probability of synchronization in a given step is analyzed, which converges to a geometric distribution for long synchronization times. From this asymptotic behavior the number of steps required to synchronize an ensemble of independent random walk pairs is deduced. Here the synchronization time increases with the logarithm of the ensemble size. The results of this model are compared to those observed in neural synchronization.
description: 10 pages, 7 figures; introduction changed, typos corrected
A case study applying a novel approach to estimate the social impact of a medical innovation - the use of secukinumab for psoriatic arthritis in Germany
Creators: name: Himmler, Sebastian
name: Mueller, Malina
name: Bintu Sherif
name: Ostwald, Dennis
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Neuroscience
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Psoriatic arthritis (PsA) is associated with serious productivity impairment. Secukinumab, a fully human IL-17A inhibitor, provides sustained relief from PsA symptoms. This study estimates the societal economic benefits of using secukinumab instead of conventional disease-modifying anti-rheumatic drugs (DMARDs) for treating patients with active PsA in Germany from 2016 to 2030. A Markov and a population model simulated the functional impairment of German PsA patients. The relationship between functional impairment and work productivity was used to determine the productivity difference in the populations treated with secukinumab and csDMARDs. The corresponding gains in productive time were allocated to paid and unpaid activities and valued according to gross value added (GVA). Since increased productivity has the potential to stimulate greater macroeconomic effects, indirect and induced GVA effects were calculated as well. The use of secukinumab reduces the productivity impairment in the target population on average by 13 percentage points. This difference could generate 32 million active and productive hours until the year 2030, which translates to GVA equivalents of €1.3 billion. Including indirect and induced effects yield an economic estimate of €2.7 billion GVA equivalent. The improvements in PsA-related functional impairment could lead to sizable productivity effects within the economy.
Macarthuriaceae Christenh.
Creators: name: Christenhusz, Maarten J. M.
name: Brockington, Samuel F.
name: Christin, Pascal-Antoine
name: Sage, Rowan F.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Caryophyllales
Macarthuriaceae

description: Macarthuriaceae Christenh., fam. nov.
 Type of the family:— Macarthuria Hügel ex Endlicher (1837: 11).
These are rigid or wiry, rush-like, perennial herbs or subshrubs with green stems. Leaves are alternate, with or without a petiole, lacking stipules. The blades are simple, linear or progressively reduced upwards to scales along the stem. Leaf blades have entire margins and obscure venation. Inflorescences are many-flowered, axillary or terminal compound cymes, or flowers solitary in the leaf axils. Flowers are actinomorphic and bisexual. The five or ten sepals are in two whorls and fused at the base. Petals are five and free, or absent. The eight stamens have filiform filaments that are fused to each other at the base. Anthers are basifixed and opening by lengthwise slits. The superior ovary is composed of three carpels that are fused into a single (or rarely three) locule(s). The three stylodes are fused into a single style at the base, each with an unlobed stigma. Fruits are loculicidal capsules with up to ten seeds.
The family differs from Molluginaceae and Microteaceae in having five petals (usually absent in Molluginaceae and Microteaceae), the basifixed anthers (dorsifixed in Molluginaceae and Microteaceae) and the three carpels forming a single locule (one to five carpels each forming a locule in Molluginaceae). They are shrubs that predominately photosynthesize with their rush-like stems; the leaves are often reduced and insignificant.
description: Published as part of Christenhusz, Maarten J. M., Brockington, Samuel F., Christin, Pascal-Antoine & Sage, Rowan F., 2014, On the disintegration of Molluginaceae: a new genus and family (Kewa, Kewaceae) segregated from Hypertelis, and placement of Macarthuria in Macarthuriaceae, pp. 238-242 in Phytotaxa 181 (4) on page 240, DOI: 10.11646/phytotaxa.181.4.4, http://zenodo.org/record/5146298
Relativistic corrections to gluon fragmentation into spin-triplet S-wave quarkonium
Creators: name: Bodwin, Geoffrey T.
name: Lee, Jungil
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We use the NRQCD factorization formalism to calculate the relativistic corrections to the fragmentation function for a gluon fragmenting into a spin-triplet S-wave heavy quarkonium. We make use of the gauge-invariant formulation of the fragmentation function of Collins and Soper. The color-octet contribution receives a large, negative relativistic correction, while the color-singlet contribution receives a large, positive relativistic correction. The considerable decrease in the color-octet contribution requires a corresponding increase in the phenomenological value of the leading color-octet matrix element in order to maintain a fit to the Fermilab Tevatron data.
description: version to appear in Phys. Rev. D, 19 pages, RevTeX, 3 Postscript figures, Mathematica notebook file integrands.nbx contains color-singlet integrands
Neuro-Symbolic Contrastive Learning for Cross-domain Inference
Creators: name: Liu, Mingyue
name: Ueda, Ryo
name: Wan, Zhen
name: Inoue, Katsumi
name: Willcocks, Chris G.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Machine Learning (cs.LG)
subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Pre-trained language models (PLMs) have made significant advances in natural language inference (NLI) tasks, however their sensitivity to textual perturbations and dependence on large datasets indicate an over-reliance on shallow heuristics. In contrast, inductive logic programming (ILP) excels at inferring logical relationships across diverse, sparse and limited datasets, but its discrete nature requires the inputs to be precisely specified, which limits their application. This paper proposes a bridge between the two approaches: neuro-symbolic contrastive learning. This allows for smooth and differentiable optimisation that improves logical accuracy across an otherwise discrete, noisy, and sparse topological space of logical functions. We show that abstract logical relationships can be effectively embedded within a neuro-symbolic paradigm, by representing data as logic programs and sets of logic rules. The embedding space captures highly varied textual information with similar semantic logical relations, but can also separate similar textual relations that have dissimilar logical relations. Experimental results demonstrate that our approach significantly improves the inference capabilities of the models in terms of generalisation and reasoning.
description: In Proceedings ICLP 2024, arXiv:2502.08453
Macroeconomic Determinants of Relative Wheat Prices: Integrating the Short Run and Long Run
Creators: name: Denbaly, Mark
name: Torgerson, David
name: Denbaly, Mark
name: Torgerson, David
Publisher: name: Unknown
Year: 1992
Subjects: subject: International Relations/Trade
subject: relative prices
subject: real exchange rate
subject: real rate of interest
subject: cointegration
subject: commodity prices
subject: overshooting
subject: and error-correction models

description: Prior empirical studies ignore that markets, subject to overshooting, determine farm prices and macroeconomic variables jointly. So, these elasticities are statistically unreliable. Using cointegration, with all variables determined simultaneously, we find that instantaneous wheat price elasticities with respect to the real exchange rate and interest rate are -127 and -197, respectively. Here, we measure the amount that the wheat price overshoots its equilibrium. The extent of overshooting differs for different monetary policy regimes. However, 57 percent of the deviation from longrun equilibrium is corrected within two quarters.
The compliance and cost-effectiveness of smartphone urinalysis albumin screening for people with diabetes in England
Creators: name: Shore, Judith
name: Green, Michelle
name: Hardy, Andrew
name: Livesey, Deborah
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: People with diabetes are at increased risk of developing chronic kidney disease (CKD) and should undergo annual screening, but adherence is poor. A home urinalysis self-test has been developed to improve compliance with screening. The objective of this paper is to report on a clinical evaluation and economic analysis of home urinalysis self-testing. People with diabetes who had not undergone screening within the previous 18 months were recruited to a single-arm clinical evaluation to assess the uptake and compliance of home urinalysis self-testing. An economic evaluation assessed the likely cost-consequences of the use of home urinalysis self-testing over a lifetime time horizon. A total of 2,196 people with diabetes were contacted as part of the clinical evaluation. Of these, 695 people agreed to be sent a home urinalysis self-testing kit and 499 people completed and returned the test. Cost savings of £2,008 per person were estimated over a lifetime due to increased CKD diagnosis and reduced progression to end stage renal disease. Home urinalysis self-testing of ACR in people with diabetes is estimated to be a cost-effective use of NHS resources in England in people who would otherwise not comply with standard care.
MOESM1 of Age-specific incidence of allergic and non-allergic asthma
Creators: name: Pakkasela, Johanna
name: Pinja Ilmarinen
name: Honkamäki, Jasmin
name: Tuomisto, Leena
name: Andersén, Heidi
name: Piirilä, Päivi
name: Hisinger-Mölkänen, Hanna
name: Sovijärvi, Anssi
name: Backman, Helena
name: Lundbäck, Bo
name: Rönmark, Eva
name: Kankaanranta, Hannu
name: Lehtimäki, Lauri
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer

description: Additional file 1: Figure S1. Relative proportions of allergic (subjects with either allergic rhinitis or allergic conjunctivitis or both) and non-allergic (subjects without allergic rhinitis or allergic conjunctivitis) cases of new asthma diagnoses in different age groups.
Machine-Learning Detection of the Berezinskii-Kosterlitz-Thouless Transitions
Creators: name: Mochizuki, Masahito
name: Miyajima, Yusuke
Publisher: name: arXiv
Year: 2025
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The Berezinskii-Kosterlitz-Thouless (BKT) transition is a typical topological phase transition defined between binding and unbinding states of vortices and antivortices, which is not accompanied by spontaneous symmetry breaking. It is known that the BKT transition is difficult to detect from thermodynamic quantities such as specific heat and magnetic susceptibility because of the absence of anomaly in free energy and significant finite-size effects. Therefore, methods based on statistical mechanics which are commonly used to discuss phase transitions cannot be easily applied to the BKT transition. In recent years, several attempts to detect the BKT transition using machine-learning methods based on image recognition techniques have been reported. However, it has turned out that the detection is difficult even for machine learning methods because of the absence of trivial order parameters and symmetry breaking. Most of the methods proposed so far require prior knowledge about the models and/or preprocessing of input data for feature engineering, which is problematic in terms of the general applicability. In this article, we introduce recent development of the machine-learning methods to detect the BKT transitions in several spin models. Specifically, we demonstrate the success of two new methods named temperature-identification method and phase-classification method for detecting the BKT transitions in the q-state clock model and the XXZ model. This progress is expected to sublimate the machine-learning-based study of spin models for exploring new physics beyond simple benchmark test.
description: 13 pages, 12 figures, published in Journal of the Physical Society of Japan as Special Topics for machine learning physics
Invisibility of female participants in midlife and beyond in sport and exercise science research: a call to action
Creators: name: Olenick, Alyssa
name: Cowley, Emma
name: Moore, Sam
name: McNulty, Kelly
Publisher: name: BMJ
Year: 2024

description:
As the number of females participating in sport and exercise has increased and moved towards parity with males, understanding the specific needs of sportswomen has become increasingly essential. Sadly, the imbalance between the representation of females and males in sport and exercise science research is well-known. For example, in 2021, we published ‘Invisible Sportswomen’: The Sex Data Gap in Sport and Exercise Science Research, which conducted an exploration of the ratio of males and females as participants in sport and exercise science research.
Perspective on Farm Size and Structure Provided by Value-Added Measures
Creators: name: Stanton, Bernard F.
name: Jinkins, John E.
name: Ahearn, Mary Clare
name: Hanson, Gregory D.
name: Stanton, Bernard F.
name: Jinkins, John E.
name: Ahearn, Mary Clare
name: Hanson, Gregory D.
Publisher: name: Unknown
Year: 1992
Subjects: subject: Farm Management
subject: net value-added
subject: size distribution
subject: farm structure

description: Much wider use of net value-added, instead of gross sales, can lend perspective on how farm size and structure are changing in the United States. Net value-added is changing a more appropriate economic measure to use in comparing farms by size or type on a consistent basis. Net value-added emphasizes the net returns to farm households from the use of their land, labor, capital, and management in agricultural production. Net value-added as a percentage of gross farm income is highest (over 60 percent) on vegetable, greenhouse and nursery, and cash grain farms. It is much lower on livestock farms that buy substantial amoungs of their inputs (fed cattle and hogs). Wider use of net value-added directs attention to the economic impact of resources used in agricultural production in the form of returns to those resources.
Direct cost of Parkinson’s disease in a health system with high judicialization: evidence from Colombia
Creators: name: Prada, Sergio I.
name: Pérez, Ana Melissa
name: Valderrama–Chaparro, Jaime
name: Molina–Echeverry, María Isabel
name: Orozco, Jorge Luis
name: Takeuchi, Yuri
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Objective: To estimate all-claims-all-conditions expenditures paid for by health plans for patients suffering from Parkinson´s disease (PD). Methods: Using administrative claims data from two health maintenance organizations for 2014 and 2015 in Colombia, we identified 2,917 patients with PD by applying an algorithm that uses International Statistical Classification of Diseases and Related Health Problems and Anatomical Therapeutic Chemical Classification System codes. Descriptive statistics were applied to compute unadjusted all-cause median costs. A generalized linear model was used to estimate adjusted and attributable direct costs of advanced PD. Results: Approximately 30% of the all-cause direct costs were associated with technologies not included in universal health coverage benefit packages. In 2015, the annual median interquartile range per patient all-cause direct costs to insurers was USD1,576 (605–3,617). About 16% of patients had advanced PD. Regression analysis estimated that additional costs attributable to advanced PD was USD3,416 (p = 0.000). Multimorbidity was highly prevalent, and 96% of PD patients had at least one other chronic condition. Conclusions: In the context of high judicialization, patients suffering from PD must increasingly use the judicial system to access treatment. To promote more equitable and efficient access benefit packages, developing countries must consider more thoroughly the needs of these patients.
Architecture for Simulating Behavior Mode Changes in Norm-Aware Autonomous Agents
Creators: name: Glaze, Sean
name: Inclezan, Daniela
Publisher: name: arXiv
Year: 2025
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences
subject: D.1.6; D.3

description: This paper presents an architecture for simulating the actions of a norm-aware intelligent agent whose behavior with respect to norm compliance is set, and can later be changed, by a human controller. Updating an agent's behavior mode from a norm-abiding to a riskier one may be relevant when the agent is involved in time-sensitive rescue operations, for example. We base our work on the Authorization and Obligation Policy Language AOPL designed by Gelfond and Lobo for the specification of norms. We introduce an architecture and a prototype software system that can be used to simulate an agent's plans under different behavior modes that can later be changed by the controller. We envision such software to be useful to policy makers, as they can more readily understand how agents may act in certain situations based on the agents' attitudes towards norm-compliance. Policy makers may then refine their policies if simulations show unwanted consequences.
description: In Proceedings ICLP 2024, arXiv:2502.08453
The origin of metal-poor and metal-rich globular clusters in E-MOSAICS
Creators: name: Reina-Campos, Marta
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: It has been a long-standing open question why observed globular cluster (GC) populations of different metallicities differ in their ages and spatial distributions, with metal-poor GCs being the older and radially more extended of the two. We use the suite of 25 Milky Way-mass cosmological zoom-in simulations from the E-MOSAICS project, which self-consistently model the formation and evolution of stellar clusters and their host galaxies, to understand the properties of observed GC populations. We find that the different ages and spatial distributions of metal-poor and metal-rich GCs are the result of regular cluster formation at high redshift in the context of hierarchical galaxy assembly. We also find that metallicity on its own is not a good tracer of accretion, and other properties, such as kinematics, need to be considered.
description: 4 pages, 2 figures, to appear in Proceedings IAU Symposium n. 351, "Star Clusters: From the Milky Way to the Early Universe", 2019
On a stochastic Camassa-Holm type equation with higher order nonlinearities
Creators: name: Rohde, Christian
name: Tang, Hao
Publisher: name: arXiv
Year: 2020
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: The subject of this paper is a generalized Camassa-Holm equation under random perturbation. We first establish local existence and uniqueness results as well as blow-up criteria for pathwise solutions in the Sobolev spaces $H^s$ with $s>3/2$. Then we analyze how noise affects the dependence of solutions on initial data. Even though the noise has some already known regularization effects, much less is known concerning the dependence on initial data. As a new concept we introduce the notion of stability of exiting times and construct an example showing that multiplicative noise (in Itô sense) cannot improve the stability of the exiting time, and simultaneously improve the continuity of the dependence on initial data. Finally, we obtain global existence theorems and estimate associated probabilities.
Cost and utility in immunocompromised subjects who developed herpes zoster during the randomized V212 inactivated varicella-zoster vaccine (ZVIN) trial
Creators: name: Eriksson, Jennifer
name: Hunger, Matthias
name: Bourhis, François
name: Thorén, Robyn
name: Popmihajlov, Zoran
name: Finelli, Lynn
name: Yiling Jiang
Publisher: name: Taylor & Francis
Year: 2019
Subjects: Space Science
Medicine
Neuroscience
Pharmacology
Science Policy

description: Objectives: Immunocompromised subjects are at increased risk for herpes zoster (HZ) and HZ-related complications, such as post-herpetic neuralgia (PHN). We describe health utilities, health care resource utilization (HCRU), productivity loss and health care costs in recipients of autologous hematopoietic stem-cell transplantation (Auto-HSCT) who developed confirmed HZ in the phase 3 clinical trial. Methods: HCRU, costs, and EQ-5D-3L utility were assessed for 155 confirmed HZ cases observed after receiving inactivated varicella-zoster virus (VZV) vaccine (ZVIN) or placebo. In a prospective, longitudinal 6-month follow up, costs and utilities were analyzed for two health states, HZ without PHN and HZ with PHN. Results: There was a clinically relevant difference in utility between HZ without PHN (mean 0.814) and HZ with PHN (0.729). The disutility for HZ without PHN was estimated to −0.117 and to −0.186 for HZ with PHN. Direct costs (2017 USD) associated with a HZ without PHN episode and HZ with PHN episode was estimated at $3,412 and $3,711, respectively, of which hospitalizations accounted for 90% of the costs. Expert opinion: Both HZ and PHN are associated with considerable disutility in recipients of Auto-HSCT. Costs were comparable to published estimates in other immunocompromised subjects. The trial is registered at ClinicalTrials.gov (CT.gov identifier: NCT01229267).
Kewaceae Christenh.
Creators: name: Christenhusz, Maarten J. M.
name: Brockington, Samuel F.
name: Christin, Pascal-Antoine
name: Sage, Rowan F.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Caryophyllales
Kewaceae

description: Kewaceae Christenh., fam. nov.
 Type of the family:— Kewa Christenh., gen. nov.
These are annual or perennial herbs that can be slightly woody. Their leaves are alternate or in false whorls, usually more or less fasciculate at the stem tips, succulent, linear and terete. Stipules are present and fused to the base of the blade, sheathing the stem to different degrees. Inflorescences are terminal or apparently axillary, long-stalked (false) umbels. Flowers are bisexual and actinomorphic and have a whorl of five free sepals, of which three or four become petal-like (usually white or pink), but true petals are absent. The five to 15 (rarely fewer) stamens have shortly fused filaments and dorsifixed anthers opening by longitudinal slits. The superior ovary is composed of three to five fused carpels and is topped by short, fleshy stigmatic crests. The fruit is a membranaceous capsule that opens loculicidally. The family includes the single genus Kewa.
description: Published as part of Christenhusz, Maarten J. M., Brockington, Samuel F., Christin, Pascal-Antoine & Sage, Rowan F., 2014, On the disintegration of Molluginaceae: a new genus and family (Kewa, Kewaceae) segregated from Hypertelis, and placement of Macarthuria in Macarthuriaceae, pp. 238-242 in Phytotaxa 181 (4) on page 240, DOI: 10.11646/phytotaxa.181.4.4, http://zenodo.org/record/5146298
title: Producing the just city: Self-organising ULs for the re-appropriation of public spaces
Creators: name: Monno, Valeria
name: Barbanente, Angela
Publisher: name: Tracce Urbane. Rivista Italiana Transdisciplinare di Studi Urbani
Year: 2018

description: Abstract

In the contemporary city, the forms of re-appropriation of degraded and abandoned urban spaces by citizens have profoundly changed. Usual antagonistic forms of citizens' self-organisation have been increasingly replaced by new forms of interaction between citizens and institutions. These have arisen great enthusiasm as innovative urban policies that seem to open up the possibility of recovering abandoned urban spaces, which was unthinkable in the logic of top-down or dialogic approaches. In many cases their transformative potential was taken for granted, and has not been explored the possibility that such policies become means of control and injustice, and spaces where 'citizens' are used to offset the disappearance of opportunities for urban democracy and social support through the welfare state.
Assuming the program of Apulia Region "Urban Laboratories: old buildings for young ideas" as case study, our paper reflects on the ability of these interactive forms of self-organization to favour the emergence of real democratic civic re-appropriation of abandoned areas by claiming their character of 'public spaces'.

Abstract

Nella città contemporanea, le forme di of riappropriazione da parte dei cittadini di spazi urbani degradati e abbandonati sono molto cambiate. Alle consuete forme antagonistiche di autorganizzazione dei cittadini si sono progressivamente sostituite nuove forme basate sull'interazione fra cittadini e istituzioni. Queste hanno suscitato grande entusiasmo in quanto considerate capaci di aprire possibilità di recupero di spazi urbani abbandonati, inimmaginabili utilizzando approcci top-down o dialogici. Enfatizzandone le potenzialità trasformative, non si è indagata la possibilità di rafforzamento del controllo e dell'ingiustizia sociale, o di uso dei 'cittadini' per compensare la scomparsa di opportunità di democrazia urbana e di politiche di welfare.
Indagando il programma della Regione Puglia "Laboratori Urbani: vecchi edifici per giovani idee", il contributo riflette sulla capacità di queste forme interattive di autorganizzazione di favorire una riappropriazione civica delle aree urbane in abbandono realmente democratica, rivendicandone il carattere di 'spazi pubblici'.
description: Tracce Urbane. Rivista Italiana Transdisciplinare di Studi Urbani, No 3 (2018): Spazi che abilitano/ Enabling Space
СОСТОЯНИЕ СТРАХОВОЙ ГРАМОТНОСТИ В УЗБЕКИСТАНЕ И ПУТИ ЕЕ ПОВЫШЕНИЯ
Creators: name: Эргашева, Фарангиз
Publisher: name: Zenodo
Year: 2024

description: Страхование играет решающую роль в финансовом благополучии людей, а также для общества в целом.
Generalized Master Equation Approach to Time-Dependent Many-Body Transport
Creators: name: Moldoveanu, Valeriu
name: Manolescu, Andrei
name: Gudmundsson, Vidar
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We recall theoretical studies on transient transport through interacting mesoscopic systems. It is shown that a generalized master equation (GME) written and solved in terms of many-body states provides the suitable formal framework to capture both the effects of the Coulomb interaction and electron--photon coupling due to a surrounding single-mode cavity. We outline the derivation of this equation within the Nakajima-Zwanzig formalism and point out technical problems related to its numerical implementation for more realistic systems which can neither be described by non-interacting two-level models nor by a steady-state Markov-Lindblad equation. We first solve the GME for a lattice model and discuss the dynamics of many-body states in a two-dimensional nanowire, the dynamical onset of the current-current correlations in electrostatically coupled parallel quantum dots and transient thermoelectric properties. Secondly, we rely on a continuous model to get the Rabi oscillations of the photocurrent through a double-dot etched in a nanowire and embedded in a quantum cavity. A~many-body Markovian version of the GME for cavity-coupled systems is also presented.
description: 39 pages, 13 figures
Multi-Enterprising Farm Households: The Importance of Their Alternative Business Ventures in the Rural Economy
Creators: name: Vogel, Stephen J.
name: Vogel, Stephen J.
Publisher: name: Unknown
Year: 2012
Subjects: subject: Community/Rural/Urban Development
subject: onfarm diversification
subject: off-farm businesses
subject: portfolio entrepreneur
subject: farm household typology
subject: nonfarm employment
subject: direct sales

description: Almost a third of U.S. farm households generate income by engaging in business ventures independent of commodity production, with distinctly different community and household benefits. In 2007, 686,600 farm households engaged in 791,000 income-generating activities distinct from commodity production, creating $26.7 billion in household income. Onfarm diversification activities like agritourism and off-farm business ventures each accounted for about half of these activities, but off-farm businesses generated about 80 percent of total alternative (i.e., noncommodity) business income earned by farm households, creating the largest impact on the local economy. Off-farm businesses operated by farm households contributed an estimated $54.6 billion in value-added income to the gross regional products of their local economies and paid out $24.5 billion in wages and salaries to 853,100 part-time and full-time employees. In general, the share of the local employment base accounted for by farmer-owned off-farm businesses was higher in more rural counties.
Mind the Gaps: Logical English, Prolog, and Multi-agent Systems for Autonomous Vehicles
Creators: name: Sartor, Galileo
name: Wyner, Adam
name: Contissa, Giuseppe
Publisher: name: arXiv
Year: 2025
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Computation and Language (cs.CL)
subject: Logic in Computer Science (cs.LO)
subject: Multiagent Systems (cs.MA)
subject: FOS: Computer and information sciences

description: In this paper, we present a modular system for representing and reasoning with legal aspects of traffic rules for autonomous vehicles. We focus on a subset of the United Kingdom's Highway Code (HC) related to junctions. As human drivers and automated vehicles (AVs) will interact on the roads, especially in urban environments, we claim that an accessible, unitary, high-level computational model should exist and be applicable to both users. Autonomous vehicles introduce a shift in liability that should not bring disadvantages or increased burden on human drivers. We develop a system "in silico" of the model. The proposed system is built of three main components: a natural language interface, using Logical English, which encodes the rules; an internal representation of the rules in Prolog; and an multi-agent-based simulation environment, built in NetLogo. The three components interact: Logical English is translated into and out of Prolog (along with some support code); Prolog and NetLogo interface via predicates. Such a modular approach enables the different components to carry different "burdens" in the overall system; it also allows swapping of modules. Given NetLogo, we can visualize the effect of the modeled rules as well as validate the system with a simple dynamic running scenario. Designated agents monitor the behaviour of the vehicles for compliance and record potential violations where they occur. The information on potential violations is then utilized by Validators, to determine whether the violation is punishable, differentiating between exceptions and cases.
description: In Proceedings ICLP 2024, arXiv:2502.08453