cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Modelling Belgian coastal zone and Scheldt mouth area: sub report 12. Scaldis-Coast model – Model setup and validation of the 2D hydrodynamic model
Creators: name: Kolokythas, Gerasimos
name: De Maerschalck, Bart
name: Wang, L.
name: Fonias, S.
name: Breugem, A.
name: Vanlede, Joris
name: Mostaert, Frank
Publisher: name: Flanders Hydraulics Research
Year: 2021

description: With the increasing awareness of sea level rise, the Flemish Authorities initiated the Complex Project Kustvisie (CPKV) in order to start together with all involved stakeholders to define the overall long-term coastal defence strategy for the Belgian Coast. To analyze the impact of sea level rise on the morphology of the coast and to assess mitigation measures on their efficiency the need for a flexible coastal model for the Belgian coast and Scheldt mouth area was revealed.Therefore, in 2015 it was decided to build an integral coastal model within the TELEMAC-MASCARET model suite. The present report describes the setup and validation of the two-dimensional hydrodynamic model. The hydrodynamic model forms the basis of the final goal: the morphodynamic model. The hydrodynamic model will be coupled to the TOMAWAC spectral wave model and SISYPHE sediment transport and bed update model. The model is validated by comparison of the numerically predicted water levels and velocities against measured water levels, stationary velocities and velocities along transects (ADCP sailed) at several locations at the coast and the Western Scheldt estuary. The performance of Scaldis-Coast is found to be good at the Belgian coast but also in The Western Scheldt. For the water levels the total RMSE increases from 9 cm in the North Sea to 13 cm in the Western Scheldt towards Antwerp. The absolute value of the bias of water levels is equal or lower than 5 cm at most stations.The Scaldis-Coast performs good in predicting the velocities at the considered coastal locations, presenting RMSE of velocity magnitude which is in general around 0.15 m/s.The hydrodynamic model is available at the Flanders Hydraulics Research model repository: https://wlsubversion.br>vlaanderen.be/!/#repoSpNumMod/view/head/TELEMAC/Scaldis-Kust/15_068%20Complex%20Model%20Kustvisie%202021/1_2D_HYDRODYNAMICS.
description: Title : FHR reports. Flanders Hydraulics Research: Antwerp Volume : 15_068_12 Issue : Pagination : VIII, 66 + 40 p. app.
Three Neutrino Flavors are Enough
Creators: name: Acker, A.
name: Pakvasa, S.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: It is shown that it is possible to account for all three experimental indications for neutrino oscillations with just three neutrino flavors. In particular, we suggest that the solar and atmospheric neutrino anomalies are to be explained by the same mass difference and mixing. Possible implications and future tests of the resulting mass-mixing pattern are given.
description: 15 pages, LATEX format. 5 figures. Replaced 1 figure and corrected typographical errors
title: ESLO1: entretien 017_A
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
Stabilization of Hfq-mediated translational repression by the co-repressor Crc in Pseudomonas aeruginosa.
Creators: name: Malecka, Ewelina M
name: Bassani, Flavia
name: Dendooven, Tom
name: Sonnleitner, Elisabeth
name: Rozner, Marlena
name: Albanese, Tanino G
name: Resch, Armin
name: Luisi, Ben
name: Woodson, Sarah
name: Bläsi, Udo
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021

description: Funder: AstraZeneca
description: In Pseudomonas aeruginosa the RNA chaperone Hfq and the catabolite repression control protein (Crc) govern translation of numerous transcripts during carbon catabolite repression. Here, Crc was shown to enhance Hfq-mediated translational repression of several mRNAs. We have developed a single-molecule fluorescence assay to quantitatively assess the cooperation of Hfq and Crc to form a repressive complex on a RNA, encompassing the translation initiation region and the proximal coding sequence of the P. aeruginosa amiE gene. The presence of Crc did not change the amiE RNA-Hfq interaction lifetimes, whereas it changed the equilibrium towards more stable repressive complexes. This observation is in accord with Cryo-EM analyses, which showed an increased compactness of the repressive Hfq/Crc/RNA assemblies. These biophysical studies revealed how Crc protein kinetically stabilizes Hfq/RNA complexes, and how the two proteins together fold a large segment of the mRNA into a more compact translationally repressive structure. In fact, the presence of Crc resulted in stronger translational repression in vitro and in a significantly reduced half-life of the target amiE mRNA in vivo. Although Hfq is well-known to act with small regulatory RNAs, this study shows how Hfq can collaborate with another protein to down-regulate translation of mRNAs that become targets for the degradative machinery.
Additional file 2: of Impact of insecticide-treated bednets and indoor residual spraying in controlling populations of Phlebotomus duboscqi, the vector of Leishmania major in Central Mali
Creators: name: Cheick Coulibaly
name: Bourama Traore
name: Dicko, Adama
name: Sibiry Samake
name: Sissoko, Ibrahim
name: Anderson, Jennifer
name: Valenzuela, Jesus
name: Sekou Traore
name: Ousmane Faye
name: Shaden Kamhawi
name: Oliveira, Fabiano
name: Seydou Doumbia
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Computational Biology

description: Table S2. Meteorological information for the region of Segou, 2004 to 2017. (DOCX 19 kb)
Microscopy and chemical analyses reveal flavone-based woolly fibres extrude from micron-sized holes in glandular trichomes of Dionysia tapetodes.
Creators: name: Bourdon, Matthieu
name: Gaynord, Josephine
name: Müller, Karin H
name: Evans, Gareth
name: Wallis, Simon
name: Aston, Paul
name: Spring, David R
name: Wightman, Raymond
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Cell wall
Vacuole
Flavone
Wool
Glandular trichome
Farina
Dionysia
Hydroxyflavone
Primulaceae
Flavones
Microscopy
Microscopy, Electron
Trichomes

description: BackgroundDionysia tapetodes, a small cushion-forming mountainous evergreen in the Primulaceae, possesses a vast surface-covering of long silky fibres forming the characteristic "woolly" farina. This contrasts with some related Primula which instead form a fine powder. Farina is formed by specialized cellular factories, a type of glandular trichome, but the precise composition of the fibres and how it exits the cell is poorly understood. Here, using a combination of cell biology (electron and light microscopy) and analytical chemical techniques, we present the principal chemical components of the wool and its mechanism of exit from the glandular trichome.ResultsWe show the woolly farina consists of micron-diameter fibres formed from a mixture of flavone and substituted flavone derivatives. This contrasts with the powdery farina, consisting almost entirely of flavone. The woolly farina in D. tapetodes is extruded through specific sites at the surface of the trichome's glandular head cell, characterised by a small complete gap in the plasma membrane, cell wall and cuticle and forming a tight seal between the fibre and hole. The data is consistent with formation and thread elongation occurring from within the cell.ConclusionsOur results suggest the composition of the D. tapetodes farina dictates its formation as wool rather than powder, consistent with a model of thread integrity relying on intermolecular H-bonding. Glandular trichomes produce multiple wool fibres by concentrating and maintaining their extrusion at specific sites at the cell cortex of the head cell. As the wool is extensive across the plant, there may be associated selection pressures attributed to living at high altitudes.
title: ESLO1: entretien 018_A
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
title: 02_1231
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Seniority isomerism in proton-rich N=82 isotones and its indication to stiffness of the Z=64 core
Creators: name: Matsuzawa, T.
name: Nakada, H.
name: Ogawa, K.
name: Momoki, G.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The $10^+$ and $27/2^-$ isomers of the $Z>64$, $N=82$ nuclei are investigated in the shell model framework. We derive an extended seniority reduction formula for the relevant $E2$ transition strengths. Based on the extended formula, as well as on the approximate degeneracy among the $0h_{11/2}$, $2s_{1/2}$ and $1d_{3/2}$ orbits, we argue that the $B(E2)$ data require the $^{146}$Gd core excitation. The energy levels of both parities and the $B(E2)$ values are simultaneously reproduced by a multi-$j$ shell model calculation with the MSDI, if the excitations from $(0g_{7/2}1d_{5/2})$ to $(0h_{11/2}2s_{1/2}1d_{3/2})$ are taken into account.
description: To be published in Phys. Rev. C, Revtex 25 pages with 9 Postscript figures
Effect of COVID-19 response policies on walking behavior in US cities.
Creators: name: Hunter, Ruth F
name: Garcia, Leandro
name: De Sa, Thiago Herick
name: Zapata-Diomedi, Belen
name: Millett, Christopher
name: Woodcock, James
name: Pentland, Alex 'Sandy'
name: Moro, Esteban
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Humans
Obesity
Walking
Prevalence
Cities
Weather
Communicable Disease Control
Health Policy
Socioeconomic Factors
Recreation
Transportation
United States
Accelerometry
Cell Phone
COVID-19

description: The COVID-19 pandemic is causing mass disruption to our daily lives. We integrate mobility data from mobile devices and area-level data to study the walking patterns of 1.62 million anonymous users in 10 metropolitan areas in the United States. The data covers the period from mid-February 2020 (pre-lockdown) to late June 2020 (easing of lockdown restrictions). We detect when users were walking, distance walked and time of the walk, and classify each walk as recreational or utilitarian. Our results reveal dramatic declines in walking, particularly utilitarian walking, while recreational walking has recovered and even surpassed pre-pandemic levels. Our findings also demonstrate important social patterns, widening existing inequalities in walking behavior. COVID-19 response measures have a larger impact on walking behavior for those from low-income areas and high use of public transportation. Provision of equal opportunities to support walking is key to opening up our society and economy.
Additional file 1: of Comparison of peak inspiratory flow rate via the Breezhaler速, Ellipta速 and HandiHaler速 dry powder inhalers in patients with moderate to very severe COPD: a randomized cross-over trial
Creators: name: Altman, Pablo
name: Wehbe, Luis
name: Juergen Dederichs
name: Guerin, Tadhg
name: Ament, Brian
name: Moronta, Miguel
name: Pino, Andrea
name: Goyal, Pankaj
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: List of Independent Ethics Committees. (DOCX 14 kb)
Equation of State of the Photoionized Intergalactic Medium
Creators: name: Hui, Lam
name: Gnedin, Nickolay Y.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We develop an efficient method to study the effects of reionization history on the temperature-density relation of the intergalactic medium in the low density limit (overdensity less than 5). It is applied to the study of photo-reionization models in which the amplitude, spectrum and onset epoch of the ionizing flux, as well as the cosmology, are systematically varied. We find that the mean temperature-density relation at z=2-4 is well approximated by a power-law equation of state for uniform reionization models. We derive analytical expressions for its evolution and exhibit its asymptotic behavior: it is found that for sufficiently early reionization, imprints of reionization history prior to z=10 on the temperature-density relation are washed out. In this limit the temperature at cosmic mean density is proportional to (Ω_b h/\sqrtΩ_0)^{1/1.7}. While the amplitude of the radiation flux at the ionizing frequency of HI is found to have a negligible effect on the temperature-density relation as long as the universe reionizes before z=5, the spectrum can change the overall temperature by about 20%, through variations in the abundances of helium species. However the slope of the mean equation of state is found to lie within a narrow range for all reionization models we study, where reionization takes place before z=5. We discuss the implications of these findings for the observational properties of the Lyman-alpha forest. In particular, uncertainties in the temperature of the intergalactic medium, due to the uncertain reionization history of our universe, introduces a 30% scaling in the amplitude of the column density distribution while the the slope of the distribution is only affected by about 5%. Finally, we discuss how a fluctuating ionizing field affects the above results. We argue that under
description: Submitted to MNRAS
title: ESLO1: entretien 019_A
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
title: ESLO1: entretien 020_A
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
Nucleon form factors: From the space-like to the time-like region
Creators: name: Meißner, Ulf-G.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: I discuss how dispersion relations can be used to analyse the nucleon electromagnetic form factors, with particular emphasis on the constraints from unitarity and pQCD. Results for nucleon radii, vector-meson couplings, the onset of pQCD and bounds on the strangeness form factors are presented. The em form factors in the time-like region reveal some interesting physics which is not yet understood in full detail. The need for a better data basis at low, intermediate and large momentum transfer and also in the time-like region is stressed.
description: 11 pp, LaTeX, uses epsf and espcrc1.sty, 6 figures, invited talk, DAPHCE 96, Frascati, November 1996, to appear in the proceedings (Nucl. Phys. A)
title: Basiswissen Internes Rechnungswesen - Eine Einführung in die Kosten- und Leistungsrechnung, 3. Auflage
Creators: name: Ostermann, Rainer
Publisher: name: Balzert Stiftung
Year: 2024
Subjects: subject: Rechnungswesen
subject: Basiswissen
subject: Kostenrechnung
subject: Leistungsrechnung
subject: Einführung

description: Sie lernen die wesentlichen Grundlagen der Kosten- und Leistungsrechnung kennen. Neben den drei Themenbereichen Kostenarten-, Kostenstellen- und Kostenträgerrechnung werden Kostenrechnungssysteme auf Voll- und Teilkostenbasis in Grundzügen behandelt. Mit der Prozesskostenrechnung und dem Target Costing werden zum Abschluss neuere Entwicklungslinien des Kostenmanagements aufgegriffen.
Folgende Themen werden in diesem Buch behandelt:
■ Mit den Grundlagen der Kosten- und Leistungsrechnung wird eine Einführung in die Aufgaben, Begrifflichkeiten und Systeme vorgenommen.
■ Eine durchgehende Fallstudie entwickelt die Kosten- und Leistungsrechnung im Rahmen der betrieblichen Praxis von einfachen Problemstellungen hin zur komplexen Anwendung.
■ Die Kostenartenrechnung dient der Erfassung und Aufbereitung der wesentlichen Daten.
■ Die Kostenstellenrechnung ermittelt im Rahmen
der Betriebsabrechnung, wo Kosten angefallen sind.
■ Die Kostenträgerstückrechnung ordnet die Kosteninformationen den Kostenträgern zu und die Kostenträgerzeitrechnung einzelnen Perioden.
■ Abschließend erfolgt die Auseinandersetzung mit der Weiterentwicklung der Kosten- & Leistungsrechnung.
Dieses Buch richtet sich an Leserinnen und Leser, die sich mit diesem Wissensgebiet erstmals intensiver befassen wollen. Hierzu zählen neben Studierenden der Ökonomie und verwandter Disziplinen auch Praktiker, die grundlegende Kenntnisse erlangen möchten.
MOESM1 of Development of a production chain from vegetable biowaste to platform chemicals
Creators: name: Schmidt, Annemarie
name: Sturm, Gunnar
name: Lapp, Christian
name: Siebert, Daniel
name: Saravia, Florencia
name: Horn, Harald
name: Ravi, Padma
name: Lemmer, Andreas
name: Gescher, Johannes
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: Plant Biology

description: Additional file 1: Table S1. Primer sequences and amplicon size for the 16S Illumina MiSeq.
title:  Implications of Climate Change for Cyanobacteria Over the Western Florida Shelf in the Gulf of Mexico
Creators: name: Osmon, Ivy Mara
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 2014

description: Concentrations of atmospheric CO2 are expected to double by year 2100 as a result of anthropogenic activities. Under elevated CO2 conditions, cyanobacteria may reallocate energy from active accumulation and transport of dissolved inorganic carbon (C) required for photosynthesis to other growth processes. Stimulation of cyanobacterial production on the Western Florida Shelf in the Gulf of Mexico (GOM) could lead to improved nutritional status for the toxic, mixotrophic dinoflagellate Karenia brevis that utilizes newly fixed N2 from co-occurring diazotrophic cyanobacteria and consumes unicellular cyanobacteria via grazing for growth. Culture studies performed by other researchers on the climate induced physiological changes in the GOM diazotroph Trichodesmium erythraeum have revealed that this ecologically important cyanobacteria fixes dinitrogen (N2) and grows at higher rates under elevated pCO2 compared to present day conditions. Research performed to determine impacts of elevated pCO2 on primary production and diazotrophic physiology in other important cyanobacterial groups, including coastal Synechococcus cf elongatus, Lyngbya spp. and unicellular diazotrophs is limited, but all currently contribute to bioavailable N pools fueling K. brevis blooms. This thesis explores the connection between elevated CO2 and stimulation of production and N2 fixation in cyanobacteria to better estimate the nutritional status of GOM phytoplankton, especially K. brevis, under future climate conditions.

Incubation experiments were performed using cultured populations of coastal S. cf elongatus and T. erythraeum, and natural populations of Trichodesmium spp., Lyngbya spp. And a mixed phytoplankton assemblage from the GOM to estimate the impact of elevated pCO2 and/or elevated temperature on their N and C physiology. Cultured populations experienced stimulation in C fixation at high pCO2 and N2 fixation was stimulated in T. erythraeum. Natural populations of Trichodesmium spp. Also experienced elevated rates of C and N2 fixation at high CO2, but significant pCO2 stimulation of production and N2 fixation was not observed in Lyngbya spp. and the mixed phytoplankton assemblage. The supply of available N and provision of prey species available to fuel K. brevis production is likely to increase under future climate conditions because dominant cyanobacteria increase primary production rates and N2 fixation under elevated pCO2 and/or temperature conditions.
title: ESLO1: entretien 021_A
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
The Globular Cluster Systems in the Coma Ellipticals. III: The Unique Case of IC 4051
Creators: name: Woodworth, S. C.
name: Harris, W. E.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Using archival \hst WFPC2 data, we derive the metallicity distribution, luminosity function, and spatial structure of the globular cluster system around IC 4051, a giant E galaxy on the outskirts of the Coma cluster core. The metallicity distribution derived from the (V-I) colors has a mean [Fe/H] = -0.3, a near-complete lack of metal-poor clusters, and only a small metallicity gradient with radius; it may, however, have two roughly equal metallicity subcomponents, centered at [Fe/H] ~ 0.0 and -1.0. The luminosity distribution (GCLF) has the Gaussian-like form observed in all other giant E galaxies, with a peak (turnover) at V = 27.8, consistent with a Coma distance of 100 Mpc. The radial profiles of both the GCS and the halo light show an unusually steep falloff which may indicate that the halo of this galaxy has been tidally truncated. Lastly, the specific frequency of the GCS is remarkably large: we find S_N = 11 +- 2, resembling the central cD-type galaxies even though IC 4051 is not a cD or brightest cluster elliptical. A formation model consistent with most of the observations would be that this galaxy was subjected to removal of a large fraction of its protogalactic gas shortly after its main phase of globular cluster formation, probably by its first passage through the Coma core. Since then, no significant additions due to accretions or mergers have taken place.
description: 24 pp. plus 13 Figures. Postscript file for the complete paper can also be downloaded from http://www.physun.mcmaster.ca/~harris/WEHarris.html. Astron.J., in press
Stress-dependent electrical transport and its universal scaling in granular materials
Creators: name: Zhai, Chongpu
name: Hanaor, Dorian
name: Proust, Gwénaëlle
name: Gan, Yixiang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We experimentally and numerically examine stress-dependent electrical transport in granular materials to elucidate the origins of their universal dielectric response. The ac responses of granular systems under varied compressive loadings consistently exhibit a transition from a resistive plateau at low frequencies to a state of nearly constant loss at high frequencies. By using characteristic frequencies corresponding to the onset of conductance dispersion and measured direct-current resistance as scaling parameters to normalize the measured impedance, results of the spectra under different stress states collapse onto a single master curve, revealing well-defined stress-independent universality. In order to model this electrical transport, a contact network is constructed on the basis of prescribed packing structures, which is then used to establish a resistor-capacitor network by considering interactions between individual particles. In this model the frequency-dependent network response meaningfully reproduces the experimentally observed master curve exhibited by granular materials under various normal stress levels indicating this universal scaling behaviour is found to be governed by i) interfacial properties between grains and ii) the network configuration. The findings suggest the necessity of considering contact morphologies and packing structures in modelling electrical responses using network-based approaches.
description: 12 pages, 4 figures
Preliminary exploration on enzyme-promoted asymmetric biomimetic synthesis of resveratrol dimers
Creators: name: Lei, Tian
name: Guan, Xingchao
name: Kang, Xiaodong
name: Wang, Yuefei
name: Han, Li
name: Li, Wenling
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Science Policy

description: The asymmetric biomimetic synthesis of resveratrol dimers was preliminarily explored using the enzyme-mediated oxidative coupling reactions of chiral resveratrol derivatives as the key step. The horseradish peroxidase-H2O2-promoted oxidations of 11,13-di-sec-butyl resveratrol ether and 3,5-dibromo-resveratrol di-sec-butyl ethers generated an 8-5-coupled intermediate and several 8-8-coupled dimeric mixtures, respectively. The acid-catalyzed debutylation of the coupling dimers and hydrogenolytic debromination synthesized natural (+)-δ-viniferin and unnatural (+)-isoquadrangularin A with undetermined stereoisomer ratio.
Squeeze-out of nuclear matter in peripheral heavy-ion collisions and momentum-dependent effective interactions
Creators: name: Larionov, A. B.
name: Cassing, W.
name: Greiner, C.
name: Mosel, U.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We perform a systematic study of in-plane and out-of-plane proton and neutron flow from nucleus-nucleus collisions within the BUU transport approach employing different parameter sets for the mean-field potentials that can be characterized by the nuclear incompressibility and the stiffness of the momentum-dependent potential. We find that a simultaneous description of the experimental data from the BEVALAC and the SIS on both the nucleon squeeze-out $v_2$ and the in-plane flow $F$ at beam energies $E_{lab} = 0.15 ÷2$ AGeV requires a mean field with strong momentum dependence, i.e. an effective Landau mass $m^* \simeq 0.68 m_0$ at normal nuclear matter density $ρ_0=0.17$ fm$^{-3}$, where $m_0=0.938$ GeV is the bare nucleon mass. Some experimental data on the squeeze-out require an even stiffer momentum dependence ($m^* \approx 0.62 m_0$). All systems investigated are found to be compatible with $m^*/m_0 = 0.65 \pm 0.03$.
description: 22 pages, 13 figures; modified figs. 7,8; added fig. 9; added references
Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection.
Creators: name: Echavarría-Consuegra, Liliana
name: Cook, Georgia M
name: Busnadiego, Idoia
name: Lefèvre, Charlotte
name: Keep, Sarah
name: Brown, Katherine
name: Doyle, Nicole
name: Dowgier, Giulia
name: Franaszek, Krzysztof
name: Moore, Nathan A
name: Siddell, Stuart G
name: Bickerton, Erica
name: Hale, Benjamin G
name: Firth, Andrew E
name: Brierley, Ian
name: Irigoyen, Nerea
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Cell Line
Vero Cells
Animals
Humans
Mice
Murine hepatitis virus
Endoribonucleases
Protein-Serine-Threonine Kinases
Viral Proteins
Antiviral Agents
Drug Delivery Systems
Virus Replication
Activating Transcription Factor 6
Unfolded Protein Response
HEK293 Cells
RNA-Seq
Chlorocebus aethiops
COVID-19

description: Funder: Medical Research Council
description: Coronavirus infection induces the unfolded protein response (UPR), a cellular signalling pathway composed of three branches, triggered by unfolded proteins in the endoplasmic reticulum (ER) due to high ER load. We have used RNA sequencing and ribosome profiling to investigate holistically the transcriptional and translational response to cellular infection by murine hepatitis virus (MHV), often used as a model for the Betacoronavirus genus to which the recently emerged SARS-CoV-2 also belongs. We found the UPR to be amongst the most significantly up-regulated pathways in response to MHV infection. To confirm and extend these observations, we show experimentally the induction of all three branches of the UPR in both MHV- and SARS-CoV-2-infected cells. Over-expression of the SARS-CoV-2 ORF8 or S proteins alone is itself sufficient to induce the UPR. Remarkably, pharmacological inhibition of the UPR greatly reduced the replication of both MHV and SARS-CoV-2, revealing the importance of this pathway for successful coronavirus replication. This was particularly striking when both IRE1α and ATF6 branches of the UPR were inhibited, reducing SARS-CoV-2 virion release (~1,000-fold). Together, these data highlight the UPR as a promising antiviral target to combat coronavirus infection.
title: ESLO1: entretien 022_A
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
Nouveau commentaire portatif de la Coutume de Normandie, Rouen, 1778, tome 2
Creators: name: Leroyer de La Tournerie, Étienne
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2019

description: Source: https://gallica.bnf.fr/ark:/12148/bpt6k9622374s/f7.image.texteImage
description: Relation: vignette : https://www.nakala.fr/data/11280/4511534d
Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins
Creators: name: Ali, Youssif M.
name: Ferrari, Matteo
name: Lynch, Nicholas J.
name: Yaseen, Sadam
name: Dudler, Thomas
name: Gragerov, Sasha
name: Demopulos, Gregory
name: Heeney, Jonathan L.
name: Schwaeble, Wilhelm J.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: complement system
subject: lectin pathway
subject: SARS-CoV-2
subject: COVID-19
subject: innate immunity

description: Early and persistent activation of complement is considered to play a key role in the pathogenesis of COVID-19. Complement activation products orchestrate a proinflammatory environment that might be critical for the induction and maintenance of a severe inflammatory response to SARS-CoV-2 by recruiting cells of the cellular immune system to the sites of infection and shifting their state of activation towards an inflammatory phenotype. It precedes pathophysiological milestone events like the cytokine storm, progressive endothelial injury triggering microangiopathy, and further complement activation, and causes an acute respiratory distress syndrome (ARDS). To date, the application of antiviral drugs and corticosteroids have shown efficacy in the early stages of SARS-CoV-2 infection, but failed to ameliorate disease severity in patients who progressed to severe COVID-19 pathology. This report demonstrates that lectin pathway (LP) recognition molecules of the complement system, such as MBL, FCN-2 and CL-11, bind to SARS-CoV-2 S- and N-proteins, with subsequent activation of LP-mediated C3b and C4b deposition. In addition, our results confirm and underline that the N-protein of SARS-CoV-2 binds directly to the LP- effector enzyme MASP-2 and activates complement. Inhibition of the LP using an inhibitory monoclonal antibody against MASP-2 effectively blocks LP-mediated complement activation. FACS analyses using transfected HEK-293 cells expressing SARS-CoV-2 S protein confirm a robust LP-dependent C3b deposition on the cell surface which is inhibited by the MASP-2 inhibitory antibody. In light of our present results, and the encouraging performance of our clinical candidate MASP-2 inhibitor Narsoplimab in recently published clinical trials, we suggest that the targeting of MASP-2 provides an unsurpassed window of therapeutic efficacy for the treatment of severe COVID-19.
Additional file 1 of Presence of comorbidities alters management and worsens outcome of patients with acute respiratory distress syndrome: insights from the LUNG SAFE study
Creators: name: Rezoagli, Emanuele
name: McNicholas, Bairbre A.
name: Madotto, Fabiana
name: Pham, Tài
name: Bellani, Giacomo
name: Laffey, John G.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Figure S1. A) ICU mortality, B) Hospital mortality and C) Limitation of care as a function of patients with different comorbidities that characterize the immune incompetence (i.e., solid neoplasm, hematological malignancy and immune-suppression). Unadjusted odds ratio calculated versus patients with no comorbidities. Figure S2. Survival analysis with competing risk to investigate the relationship between increasing number of comorbidities and the likelihood of limitation of life-sustaining measures during 90-day follow-up, considering ICU death as competing risk (i.e., event that precludes the occurrence of limitation of life-sustaining measures). Table S1. Comorbidities stratified by major geoeconomic areas of patients with ARDS. Table S2. ARDS risk factors, comorbidity profile and ICU related variables of patients with ARDS with and without comorbidities. Table S3. Management of patients with ARDS with and without comorbidities. Table S4. Development of new and/or worsening systemic acute organ dysfunction† in the study population. Table S5. Multivariate logistic regression model of factors associated with the hospital mortality in all patients. Table S6. Organ system failure considered as most important factors leading to death in ICU in non-surviving patients with ARDS at 90-day follow-up. Appendix S1.
title: ESLO1: entretien 023_A
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
Additional file 9: of Acute effects of combined exercise and oscillatory positive expiratory pressure therapy on sputum properties and lung diffusing capacity in cystic fibrosis: a randomized, controlled, crossover trial
Creators: name: Radtke, Thomas
name: Bรถni, Lukas
name: Bohnacker, Peter
name: Maggi-Beba, Marion
name: Fischer, Peter
name: Kriemler, Susi
name: Benden, Christian
name: Dressel, Holger
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Instrument inertia causes artifacts in shear rheology measurements at high frequencies. (DOCX 29 kb)
Baryogenesis from mixed particle decays
Creators: name: Covi, L.
name: Roulet, E.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider the $CP$ violating asymmetries produced in the decay of heavy particles, studying the effects of heavy particle mixing for arbitrary mass splittings. A considerable enhancement of the asymmetries is achieved when the masses of the mixed states are comparable, and the enhancement is maximal for mass splittings of the order of the widths of the decaying particles. We apply the results to the particular case of heavy scalar neutrino decays relevant for leptogenesis scenarios.
description: Latex file, 14 pgs. two figures
Chiral Light Front Perturbation Theory and the Flavor Dependence of the Light-Quark Nucleon Sea
Creators: name: Alberg, Mary
name: Miller, Gerald A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The light-quark flavor dependence of the proton sea has been of great interest for many years because of its close connection with non-perturbative effects. One hypothesis is that this dependence arises from the pion cloud of the proton. We apply light cone perturbation theory and experimental constraints to a chiral Lagrangian to compute the relevant Fock-space components of the nucleon wave function with well-defined uncertainties. Existing experimental information regarding the light flavor sea is studied, and predictions for future experimental results are provided. Future experiments have the ability to rule out this hypothesis and have profound implications for understanding the nucleon-nucleon force.
description: 10 pages, 8 figures - text expanded, figures and references added, published version
Additional file 1: of Impact of insecticide-treated bednets and indoor residual spraying in controlling populations of Phlebotomus duboscqi, the vector of Leishmania major in Central Mali
Creators: name: Cheick Coulibaly
name: Bourama Traore
name: Dicko, Adama
name: Sibiry Samake
name: Sissoko, Ibrahim
name: Anderson, Jennifer
name: Valenzuela, Jesus
name: Sekou Traore
name: Ousmane Faye
name: Shaden Kamhawi
name: Oliveira, Fabiano
name: Seydou Doumbia
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Cancer
subject: 60506 Virology
subject: Computational Biology

description: Table S1. Number of collected sand flies per household per month before and after IRS in the study area. Before IRS/LLINs, the number of collected flies per household ranged from 205 to 649 with a median of 293.00 and variance of 19778.94. After IRS/LLINs, the number of collected flies per household ranged from 25 to 159 with a median of 59.00 and variance of 3123.29. (DOCX 16 kb)
The Reaction $pp\to ppη$ and the eta-Nucleon and Nucleon-Nucleon Interactions
Creators: name: Peña, M. T.
name: Garcilazo, H.
name: Riska, D. O.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The $π$, $η$ and $ρ$ exchange contributions to the cross-section for the reaction $pp\to ppη$ near threshold are calculated with a phenomenological description of the intermediate S11 (N(1535)) resonance for all exchange mechanisms. The final state interaction in the $pp$ system is described by realistic nucleon-nucleon interaction models. The sensitivity of the results to the phenomenological models for the $η$-nucleon transition amplitude and the nucleon-nucleon interaction is explored. The $η$ exchange mechanism is found to play a dominant role. The off-shell behavior of the $ηN \to ηN$ amplitude within the $η-$exchange amplitude leads to a result significantly different from that obtained with the constant scattering length approximation. The two-nucleon amplitudes that are associated with the short range components of the nucleon-nucleon interaction contribute significantly to the cross section.
description: RevteX 22 p., 6 figures
title: ESLO1: entretien 024_A
Creators: name: Laboratoire Ligérien De Linguistique
name: Baude, Olivier
name: Dugua, Céline
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015
Subjects: subject: Français
subject: fra
subject: text_and_corpus_linguistics

description: Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
Additional file 2 of Association of bone-related biomarkers with femoral neck bone strength
Creators: name: Xia, Ning
name: Cai, Yun
name: Wang, Wei
name: Bao, Chen
name: Li, Yunming
name: Xie, Qingyun
name: Xu, Wei
name: Liu, Da
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: Additional file 2.
Understanding coronal rain dynamics through a point-mass model
Creators: name: Hillier, Andrew
name: Oliver, Ramon
name: Martínez-Gómez, David
Publisher: name: arXiv
Year: 2025
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Observations and simulations of coronal rain show that as cold and dense plasma falls through the corona it initially undergoes acceleration by gravity before the downward velocity saturates. Simulations have shown the emergence of an unexpected relation between terminal velocity of the rain and density ratio that has not been explained. Our aim is to explain this relation. In this paper we develop a simple point-mass model to understand how the evolution of the ambient corona moving with the coronal rain drop can influence the falling motion. We find that this simple effect results in the downward speed reaching a maximal value before decreasing, which is consistent with simulations with realistic coronal rain mass. These results provide an explanation for the scaling of the maximum downward speed to density ratio of the rain to the corona and as such provide a new tool that may be used to interpret observations.
description: 6 pages, 3 figures, Accepted for publication in A&A
Extending the Double Ramification Cycle using Jacobians
Creators: name: Holmes, David
name: Kass, Jesse Leo
name: Pagani, Nicola
Publisher: name: arXiv
Year: 2017
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14H40, 14K30, 14D20

description: We prove that the extension of the double ramification cycle defined by the first-named author (using modifications of the stack of stable curves) coincides with that defined by the last-two named authors (using an extended Brill-Noether locus on suitable compactified universal Jacobians). In particular, in the untwisted case we deduce that both of these extensions coincide with that constructed by Li and Graber-Vakil using a virtual fundamental class on a space of rubber maps.
description: 13 pages. Supersedes the published version. 3 small changes: (1) we correct a minus sign error in what are now Formulas 19 and 21, (2) we correct the definition of [DR] in Section 2.1, and (3) we add a citation to Dudin for Lemma 8. European Journal of Mathematics (2018)