cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Axina minas Opitz 2020, new species
Creators: name: Opitz, Weston
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cleridae
Axina
Axina minas

description: Axina minas Opitz, new species
Figures 29, 71, 101.
Type material. Holotype. Male. Type locality: Matunsinhos (Minas), Bresil, E. Gounelle, 3.4.1885 (MNHN). Paratypes. 5 specimens. Brazil: Estado do Bahia, Cachimbo,?-?-1890, Ch. Pujo (WOPC, 1); Villa Victoria,?-?- 1890, Ch. Pujol (MNHN, 1; WOPC, 1); Estado do Rio de Janeiro, Rio de Janeiro, collection date not noted, Fry (BMNH, 1); Estado do Espírito Santo, Linhares,?- X-1973, Moacir Alvarenga (MCNZ, 1).
Diagnosis. In specimens of A. minas, the pterothorax is testaceous or light castaneous, whereas in superficially similar specimens of A. lobispinula it is dark castaneous.
Description. Size. Length 8.0 mm; width 2.0 mm. Form. As in Fig. 101. Color. Cranium castaneous; antenna testaceous; thorax and abdomen flavotestaceous; elytra bicolorous, mostly testaceous, humeral angle broadly black, disc with two transverse brown fasciae, one narrow fascia at middle, second fascia angular, in front of elytral apex. Head. Cranium finely punctate, frons slightly wider than length of antennal pedicel; EW/FW 35/15. Thorax. Pronotum finely punctate, with 2 tumescences, concave at middle; PW/PL 90/120; elytra, asetiferous punctures subseriate, punctures extend slightly beyond elytral ½, width of interstitial spaces variable; EL/EW 370/70. Abdomen. Aedeagus (Fig. 29), phallobase with angle near lobes; phallobasic lobes short, slightly separated; edges of phallic plates serrate; phallobasic apodeme abbreviated.
Variation. Size. Length 6.5–9.0 mm; width 2.7– 2.2 mm. Other than body size, the available specimens are quite homogeneous.
Natural history. Specimens were collected in Brazil during March and October.
Distribution (for map see Fig. 71). This species is known from Brazil.
Etymology. The specific epithet, minas, is a noun in apposition and refers to the type locality.
description: Published as part of Opitz, Weston, 2020, Taxonomic revision of the Western Hemisphere checkered beetle genus Axina Kirby (Coleoptera: Cleridae: Clerinae), pp. 1-70 in Insecta Mundi 2020 (793) on page 26, DOI: 10.5281/zenodo.4564947
Rise up and be A Man! And stop trying to be The Man!
Creators: name: Robinson, Mason
name: Watkis, Devon
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2011

description: The lack of male role models in African American communities and the problems come from it
description: Drugs, poverty, and violence are just three of the many issues that plague the African American communities within our nation, and young black men are usually the perpetrators and the victims. Although there are many ways to solve these problems, the one major solution is for black men to stand up and show the younger generation the right way to live. There is a lack of black fathers and good role models in our nation. Without the proper guidance young black boys look to the streets for advice on how to be a man, which will only lead to disastrous futures for the younger generations.  Whether it is a doctor, lawyer, business man or cashier, these upstanding African American men need to become the role models for the young people that may already be on the streets and going down the wrong path, and get African American males to do the right thing no matter what profession they chose.
Aulogymnus gallarum Linnaeus
Creators: name: Yefremova, Zoya A.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy

description: 3. Aulogymnus gallarum (Linnaeus)
Material examined. 1 ♀, Israel, Qiryat Tiv’on, reared from Cynipidae galls of Quercus calliprinos Webb, 4.iv.1956 (M. Sternlicht).
Hosts. Ectoparasitoid of Cynipidae (Hymenoptera) on Q. ithaburensis (Yefremova et al. 2007; Askew et al. 2013).
Distribution. Israel *; Palearctic (South and Central Europe till Iran) (Bouček & Askew 1968; Bouček 1977; Kalina 1989; Vidal 2001; Yefremova 2002, Yefremova et al. 2007; Askew et al. 2013).
description: Published as part of Yefremova, Zoya A., 2015, An annotated checklist of the Eulophidae (excl. Tetrastichinae) (Hymenoptera: Chalcidoidea) of Israel, pp. 1-36 in Zootaxa 3957 (1) on page 5, DOI: 10.11646/zootaxa.3957.1.1, http://zenodo.org/record/288546
Colony Collapse Disorder: Links to pesticides and their alternatives
Creators: name: Clark, Colin
name: Mosebach, Ian
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2011

description: A study on pesticides that may be connected to colony collapse disorder, as well as natural alternatives that can substitute them
description: Colony Collapse disorder (CCD) is when all the workers in a honeybee hive abandon the hive. while there is no specific cause known for CCD, there are several pressures on honeybees that are believed to come together to make it occur (Watanabe). Pesticides, one of the believed causes of CCD, are a human pressures that can be removed from the equation by current technology. Pest control has evolved from sulfur in Mesopotamia over 4,500 years ago (Miller, GT), to deadly poisons, and finally to specific toxins developed in chemistry labs. Carbamate pesticides, organochlorine insecticides, pyrethroid pesticides, Malathion, Neonicontinoids, and Carbaryl are several pesticides that have been offered for pest control with varying degrees of toxicity and specificity. In the past, these effective methods of killing pests were important for human development of civilizations, however the sterile male/insect technique (SIT), physical techniques, cultural techniques, and biological control are natural methods of pest control that do not put pressures on honeybees and are beginning to be implemented. Biological methods, perhaps the most important of alternatives, is where humans use nematodes, fungi, bacteria, viruses, and genetic manipulation as a method of pest control by supporting natural enemies of the pests in order to subdue them (Gullen). Unfortunately, in the case of both genetic manipulation and pesticides, resistance is a common occurrence where the means of pest control can become obsolete. This can occur through pest individuals learning to avoid the pest control means implemented, by the pests becoming tolerant through the more resistant (more fit) individuals surviving, through physiological changes occurring in pest individual, or through the natural biochemical detoxification of pest individuals by developing enzymes to counteract the pathogens (Gullen). With honeybees pollinating roughly twenty billion dollars worth of food crops in the United States (Hickman) alone, farmers should take into account the consequences of using pesticides that hurt the investment they are trying to protect. No progress can occur without communication between farmers and Beekeepers, as well as important research that explores natural alternatives to pesticides.
Monitoring response to cancer therapy based on imaging changes in metabolic activity
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Monitoring response to cancer therapy including molecular targeted therapies is critical for improving efficacy of cancer treatment and to develop personalized cancer therapies. Technologies for monitoring response to cancer therapy have a significant potential to improve survival of cancer patients. Conventional clinical approaches are based on measurements of changes in tumor volume as a function of treatment. These conventional methods provide limited insight into heterogeneity within tumors and evaluation of drug resistance in cancer. To overcome these limitations, there is an unmet need to develop molecular approaches that can provide highly specific and sensitive measurement of response of individual cancer cells to therapy. To address these critical unmet needs, we propose to develop an optical molecular imaging approach for measurement of choline and glucose metabolism at a single cell resolution within a cancer tissue and its combination with a simple microfluidics based cell isolation device for quantification of metabolic activity of individual cells from isolated cytological samples. The central hypothesis of the proposed research is that measurement of changes in choline and glucose metabolic activity in individual cancer cells as a function cancer therapy will provide an early and rapid assessment of response to therapy including identification of drug resistance. The specific aims of the proposed research are: 1) Imaging changes in uptake and retention of choline and deoxyglucose in individual cells as a function of conventional chemotherapy and molecular targeted therapy in 2-d and 3-d breast cancer models; 2) Develop a micro fluidic device for isolation of individual cells from cytological samples and its combination with molecular imaging approach for rapid quantification of changes in choline and glucose metabolic activity in response to cancer therapy. The results of this proposal will provide a novel molecular imaging approach to monitor response to cancer therapy at a single cell resolution within a cancer tissue and a novel approach to characterize response to cancer therapy based on isolated cytological samples.
Physical chemistry of ionic liquids
Creators: name: Lee, Heather Yoonsoo
Publisher: name: No Publisher Supplied
Year: 2012

description: Physical chemistry of ionic liquids (ILs) is investigated. First, ILs are used as solvents for photoinduced intramolecular electron-transfer (ET) reactions of a donor-bridge- acceptor compound. The solvation dynamic effect of the ILs on the intramolecular ET is compared with that in neutral solvents. The ET rates in ionic liquids are slower and very broadly distributed compared to narrowly distributed rates in the neutral solvents. In addition, the reaction kinetics in the ILs are dynamically heterogeneous. Dynamic heterogeneity, however, is not a unique quality to ILs; glass systems also show such behavior. To determine the degree to which this dynamic heterogeneity arises from, we examine the structural heterogeneity of ILs. We study the local structure of ILs using 2D NMR spectroscopy on the set of four homologous ILs. The results suggest intermolecular interactions between hydrogen atoms on the cation ether- chains and the fluorine atoms on the anions - such interaction is not found for the octyl-chained ILs. Lastly, physical and chemical properties of novel paramagnetic ionic liquids/solids are characterized. The crystal structures of these ionic compounds are solved and the magnetic properties are reported.
Axina munda Schenkling 1900
Creators: name: Opitz, Weston
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cleridae
Axina
Axina munda

description: Axina munda Schenkling, 1900
Figures 52, 71, 100.
Axina munda Schenkling, 1900: 391. Lectotype. Male. Here selected. Type locality: Jatahy, Prov. Goyas (Brasil) (SDEI). Paralectotypes. 2 specimens. Brazil; Estado do Goiás, Goias, collection date not noted, Donckier (RMNH, 1; SDEI, 1). Corporaal 1950: 98. There is indication that Schenkling examined more than one specimen in his description of this species, but he did not select a holotype, therefore, I invoke Recommendation 73F of the ICZN (1999) and designate a lectotype for this nominal species.
Diagnosis. Distinguishable from superficially similar specimens of Axina vista by the configuration of the dark elytral markings. In A. munda specimens the 2 posterior dark markings are punctiform, whereas in A. vista
specimens these markings are transverse. Also, there are considerable differences in their aedeagi (compare Fig. 52, 39).
Redescription. Size. Length 11.0 mm; width 3.0 mm. Form. As in Fig. 100. Color. Flavotestaceous, except black in distal limit of femur, and proximal limit of tibia, and each elytron with three black spots, one spot at humeral angle, one just behind middle, and one at elytral apical 3/4 .. Head. Cranium finely punctate, frons wider than length of antennal pedicel; EW/FW 60/20. Thorax. Pronotum finely punctate, with 2 tumescences, concave at middle; PW/PL 115/160; elytra, asetiferous punctures substriate, punctures extend to slightly beyond elytron middle, interstitial spaces vary in width; EL/EW 480/100. Abdomen. Aedeagus (Fig. 52), phallobasic lobes very long, narrow, approximate; phallus abruptly narrowed, phallic plates copiously serrate; phallobasic apodeme abbreviated.
Variation. Size. Length 9.0–11.0 mm; width 2.2–2.5 mm. The black markings on the elytron disc vary in prominence.
Natural history. Specimens were collected in Bolivia during October & December.
Distribution (for map see Fig. 71). In addition to the lectotype and paralectotypes, I examined 11 specimens from: Bolivia: Departamento de Santa Cruz, Buena Vista, vicinity Hotel Flora & Fauna, 22-26-X-2002, Morris & Wappes; Andres Ibenez, Potrerillos del Guenda, 608- XII-2011, Wappes, Lingafelter, Morris, Woodley. Brazil: Estado do Goías, Jatai, collection date and collector not noted; Trindade, collection date not noted, Ch. Pujol. Ecuador, Provincia de Napo, Yasuni National Forest, no other information available. Specimens are deposited in: ACMT, MNHN, QCAZ, SDEI, and WOPC.
description: Published as part of Opitz, Weston, 2020, Taxonomic revision of the Western Hemisphere checkered beetle genus Axina Kirby (Coleoptera: Cleridae: Clerinae), pp. 1-70 in Insecta Mundi 2020 (793) on pages 26-27, DOI: 10.5281/zenodo.4564947
Cirrospilus elegantissimus Westwood
Creators: name: Yefremova, Zoya A.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy

description: 4. Cirrospilus elegantissimus Westwood
Material examined. 1 ♀, Israel, Nahal Zin, on Tamarix sp., sweeping, 6.v.1998 (I. Yarom, V. Kravchenko). Hosts. Ectoparasitoid of Rhynchaenus sp. (Coleoptera: Curculionidae); Gracillariidae (Lepidoptera) (Bouček & Askew 1968).
Distribution. Israel *; Palearctic (Bouček & Askew 1968; Zhu et al. 2002; Yefremova 2002).
description: Published as part of Yefremova, Zoya A., 2015, An annotated checklist of the Eulophidae (excl. Tetrastichinae) (Hymenoptera: Chalcidoidea) of Israel, pp. 1-36 in Zootaxa 3957 (1) on page 5, DOI: 10.11646/zootaxa.3957.1.1, http://zenodo.org/record/288546
Megafires and ecological networks
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Western montane conifer forests historically burned frequently, at low to moderate severity. However, a century of fire suppression and logging has drastically increased fuel load and thus fire risk. Climate change, and particularly the recent extreme drought, have exacerbated these risk factors, resulting in longer fire seasons, with large, high severity fires. These megafires are predicted to increase in frequency globally as the climate warms. Drastic disturbances can disrupt ecological networks, threatening ecosystem integrity and services. However, the effect of megafires on network structure and function has not yet been examined. We propose to study these effects on two tightly linked ecological networks in Californian forests: the foodweb network and the pollination network. The vast, open, and largely homogeneous landscapes created by megafires greatly change both species composition and the interaction among species through a combination of drastic changes in the identity, the spatial distribution, and the interactions among producers and consumers within these ecosystems. Similarly, fires change the abundance and timing of flower availability, through plant mortality and increased access to nutrients, water and sunlight. These changes are bound to affect pollinator populations and their foraging behavior, feeding back into plant reproductive success. We expect that these factors drive strong changes in structural properties of both ecological networks (e.g. network length, redundancy), with functional consequences for stability and service provision. To address these questions, we will collect empirical data to construct detailed trophic and pollination networks in a recent megafire in the Sierra Nevada, paired with a control site experiencing a more typical fire regime. This will allow us to contrast effects of typical versus megafire disturbances on network properties for two linked networks. We aim to develop a comprehensive approach that can be applied more broadly, in a follow-up to this project, to study variation in megafire effects, e.g., due to fire size or age. Results will help guide post-fire forest management in California, by identifying vulnerable species/interactions that require mitigation actions and/or consideration when planning management activities (e.g., salvage logging, replanting). Ultimately, this will contribute to making western forests more resilient to climate change induced novel fire regimes.
Fabrication, characterization and application of porous nano carbon composites
Creators: name: Landers, John
Publisher: name: No Publisher Supplied
Year: 2012

description: Nanotechnology is an emerging field with the promise for new materials and applications in a variety of fields including medicine, drug delivery, catalysis and sustainable energy. At the forefront of these endevours are nanocarbon materials such as carbon nanotubes and graphene. Their inclusion into a host of composite materials have endowed materials with significant properties such as enhance mechanical strength, electrical and thermal conductivity and improved functions such as drug delivery and catalysis. In many cases there is a further desire to make composites of these materials porous with a high internal surface area. Doing so will allow opportunities to optimize the pore size distribution tailored towards specific applications. It is aim of this work to demonstrate the versatility of these nanocarbon materials highlighting their usage in porous materials. The fabrication of these porous nano carbon materials is detailed through several techniques including wet spinning, sol-gel chemistry and forced impregnation. The characterization aspect is discussed at length focusing primarily on the porosimetetry results obtained from gas adsorption isotherms. Finally, the application of these composites are demonstrated in their use to enhance stem cell differentiation, as fiber composites for neural tissue engineering, catalysis and in the area of ultracapacitors.
Axina pallidioccabus Opitz 2020, new species
Creators: name: Opitz, Weston
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cleridae
Axina
Axina pallidioccabus

description: Axina pallidioccabus Opitz, new species
Figures 31, 71, 102.
Type material. Holotype. Male. Type locality: Serra de Communati (Pernambuco) (Brazil), 3-XII-1893, Gounelle (MNHN). Paratype. One specimen. Brazil: No other information available (WOPC).
Diagnosis. The members of this species resemble superficially those of A. proxima, from which pallidioccabus specimens differ by showing a pale pronotal collar, two elytral yellow fasciae, and a black elytral apex. In proxima specimens the pronotal collar is black, there is one elytral testaceous fascia, and the elytral apex is testaceous.
Description. Size. Length 7.0 mm; width 1.7 mm. Form. As in Fig. 102. Color. Forebody black, except pronotal collar testaceous; antenna testaceous; pterothorax, legs, and abdomen testaceous; elytra tricolorous, mostly testaceous in basal ½, mostly black in apical ½; each elytron with premedial and postmedial yellow fasciae that reach sutural margin. Head. Cranium finely punctate, frons wider than length of antennal pedicel; EW/FW 35/18. Thorax. Pronotum finely punctate, with 2 tumescences, concave at middle; PW/PL 73 /95; elytra with striate asetiferous punctures, latter extend backwards slightly beyond elytron middle; width of interstitial spaces variable EL/EW 290/45. Abdomen. Aedeagus (Fig. 31), phallobase narrows to short acuminate phallobasic lobes; both margins serrate; phallobasic apodeme abbreviated.
Variation. Size. Length 5.5–9.0 mm; width 1.3–2.5 mm. The brown markings on the elytral disc vary in prominence.
Natural history. Specimens were collected in Brazil during March, September, November, and December, some at 800 m.
Distribution (for map see Fig. 71). This species is known from Brazil.
Etymology. The specific epithet, pallidioccabus, is a Latin compound name derived from pallid (= pale) and occabus (= collar). I refer to the testaceous color of the pronotal collar.
description: Published as part of Opitz, Weston, 2020, Taxonomic revision of the Western Hemisphere checkered beetle genus Axina Kirby (Coleoptera: Cleridae: Clerinae), pp. 1-70 in Insecta Mundi 2020 (793) on page 27, DOI: 10.5281/zenodo.4564947
Uncinocythere cuadricuspide Hart 1962
Creators: name: Williams, Bronwyn W.
name: Weaver, Patricia G.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Ostracoda
Podocopida
Entocytheridae
Uncinocythere
Uncinocythere cuadricuspide

description: Uncinocythere cuadricuspide (Rioja, 1945) Hart, 1962
1945 Entocythere dobbini cuadricuspide n. sbsp. — Rioja: 421, 422, Fig. 3 (R, T).
1945 Entocythere dobbini multicuspide n. sbsp.— Rioja, 1945: 421, 422, Fig. 4 (R, T).
1949 Entocythere cuadricuspide n. sp. — Rioja: 323 [and as Entocythere dobbini cuadricúspide, lapsus calami], 324, 325 [as Entocythere cuadricúspide, lapsus calami], 328, Pl. II Figs. 21–23 (D, H, R, T).
1949 Entocythere dobbini multidentata.— Rioja: 325, synonymization with Entocythere cuadricuspide (T).
1959 E. cuadricuspide Rioja (1949).—Crawford: 167 (C).
1962 Uncinocythere cuadricuspide (Rioja) new combination.—Hart: 122 [as E. dobbini cuadricuspide, E. cuadricuspide, E. dobbini multicuspide], 124, 137 (C, D, T).
1968 U. caudriscuspide (Rioja, 1949).—Ferguson: 502, erroneous spelling (C, D).
1971 Uncinocythere cuadricuspide (Rioja, 1945:422).—Hobbs Jr.: 2 [as E. dobbini cuadricuspide, E. cuadricuspide, E. dobbini multicuspide, and E. dobbini multidentata], 3, 7, 14, 15 [by implication], 16, 17 [E. d. multicuspide], 20, 22–24 [and as multicuspide and multidentata], 25, 26, 43, 52, 53, Figs. 7 [by implication], 10a–f, 11 (A, C, D, H, K, R, T).
1973 Uncinocythere caudricuspide (Rioja, 1945).—Holt: 4, erroneous spelling (A).
1974 Uncinocythere cuadricuspide (Rioja, 1945). — Hart & Hart: 15 [and as E. dobbini cuadricuspide and E. dobbini multicuspide], 121, 127, 211, 234, Pl. XXXV Figs. 12–16, Pl. LVIII (C, D, H, K, T).
1974 U. cuadricuspide (Rioja, 1945:422).—Villalobos Figueroa & Hobbs: 9 (R, T).
1975 Uncinocythere cuadricuspide (Rioja, 1945).—Hart & Hart: 48 (C, D, H).
1981 U. cuadricuspida (Rioja).—Reddell: 82, erroneous spelling (D).
2014a Uncinocythere cuadricuspide (Rioja, 1945).—Mestre, Monrós & Mesquita-Joanes: 950 (C).
Remarks: Entocythere dobbini multicuspide was synonymized with E. cuadricuspide in Rioja (1949: 325),
albeit by implication; the synonymized name was E. dobbini multidentata, an erroneous substitute for E. dobbini
multicuspide. Entocythere cuadricuspide was elevated to species rank in this same publication (Rioja 1949).
description: Published as part of Williams, Bronwyn W. & Weaver, Patricia G., 2018, A historical review of the taxonomy and classification of Entocytheridae (Crustacea: Ostracoda: Podocopida), pp. 1-129 in Zootaxa 4448 (1) on page 88, DOI: 10.11646/zootaxa.4448.1.1, http://zenodo.org/record/1444492
DAB2IP regulates neuronal migration and neurite development in the developing neocortex
Creators: name: Lee, Gum Hwa
Publisher: name: No Publisher Supplied
Year: 2012

description: Dab2ip (DOC-2/DAB2 interacting protein) is a member of the Ras GTPase-activating protein (GAP) family that has been previously shown to function as a tumor suppressor in several systems. Dab2ip is also highly expressed in the brain where it interacts with Dab1, a key mediator of the Reelin pathway that controls several aspects of brain development and function.  I found that Dab2ip is highly expressed in the developing cerebral cortex, but that mutations in the Reelin signaling pathway do not affect its expression. To determine whether Dab2ip plays a role in brain development, I knocked down or over expressed it in neuronal progenitor cells of the embryonic mouse neocortex using the in utero electroporation technique. Dab2ip down-regulation severely disrupts neuronal migration, affecting preferentially late-born principal cortical neurons. Dab2ip overexpression also leads to migration defects. Structure-function experiments in vivo further show that both PH and GRD domains of Dab2ip are important for neuronal migration. A detailed analysis of transfected neurons reveals that Dab2ip down- or up-regulation disrupts the transition from a multipolar to a bipolar neuronal morphology in the intermediate zone. Knock down of Dab2ip in neurons ex-vivo indicates that this protein is necessary for proper neurite development and for the expression of several major neuronal microtubule associated proteins (MAPs), which are important for neurite growth and stabilization. To further investigate the role of Dab2ip in the developing brain, I also conducted Western blot analysis of brain lysates obtained from Dab2ip knockout mice. I found that Dab2ip deficiency results in the abnormal activity of signal transduction pathways involving the Erk1/2 and Akt kinases during early embryonic brain development, and confirmed that Dab2ip is necessary for the expression of MAPs. Furthermore, I discovered that Dab2ip is required for maintaining the normal levels of Dab1 specifically during embryonic, but not postnatal, brain development. Thus, this study identifies, for the first time, a critical role for Dab2ip in mammalian cortical development and begins to reveal molecular mechanisms that underlie this function.
Cirrospilus ingenuus Gahan
Creators: name: Yefremova, Zoya A.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy

description: 5. Cirrospilus ingenuus Gahan
Material examined. 1 ♀, Israel, Mt. Carmel, Nahal Oren, sweeping, 14.iv.2006 (A. Freidberg). 1 ♀, Hosha’ya, ex. Phyllonorycter quercifoliella (Zeller) on Quercus ithaburensis 17.iii.2013 (W. Kuslitzky).
Hosts. Ectoparasitoid of Phyllonorycter sp. and Phyllocnistis citrella Stainton (Lepidoptera: Gracillariidae) (Argov & Rössler 1996); new host-record Ph. quercifoliella on Quercus ithaburensis.
Distribution. Israel (Argov & Rössler 1996, 1998); Australia, Indo-Malayan (Argov & Rössler 1996; Lotfalizadeh & Delvare 2011), and Palearctic ecorealms (Zhu et al. 2002; Yefremova et al. 2007).
Remarks. Argov and Rössler (1996, 1998) obtained a total of 160 adults of C. ingenuus (identified as C. quadristriatus) from Thailand, Australia and Florida, of which specimens from Thailand were released in Israel starting September, 1994. Since then, 2,000 adults have been released throughout the country, with recovery observed at several release sites.
description: Published as part of Yefremova, Zoya A., 2015, An annotated checklist of the Eulophidae (excl. Tetrastichinae) (Hymenoptera: Chalcidoidea) of Israel, pp. 1-36 in Zootaxa 3957 (1) on page 5, DOI: 10.11646/zootaxa.3957.1.1, http://zenodo.org/record/288546
Small Molecule High-throughput Screen to Expand Human HSCs
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Our proposal is entitled ‘’Small Molecule High-throughput Screen to Expand Human HSCs.’ Thousands of patients need bone marrow transplants every year, some for cancers of the marrow and some for inherited diseases such as sickle cell anemia, but many lack a bone marrow donor. A bone marrow transplant provides hematopoietic (blood) stem cells (HSCs) that replace the patient’s diseased bone marrow with healthy marrow. The marrow provides all the circulating blood cells (white cells, red cells, and platelets) throughout life. While we use the name bone marrow transplant,’ more often than not, we use other sources of HSCs. One ‘other’ source is umbilical cord blood (UCB) stem cells. UCB HSCs have lots of advantages over other sources of HSCs (bone marrow or peripheral blood). For example, we can easily obtain UCB HSCs without any risk to the donor, and we can keep them stored in freezers to be ready when a patient needs them. However, most UCB samples contain too few HSCs to be use to treat people. We believe that expanding the number of HSCs in UCB samples could go a long way towards providing needed stem cells for patient requiring a bone marrow transplant but who have no donor. Such patients are unable to obtain optimal therapy and suffer serious medical consequences. Notably, specific ethnic groups, including African Americans, Asian Americans, and people of Hispanic descent are more likely to not have a proper HSC donor than are people of Northern European ancestry. This grant proposal will use sophisticated techniques (small molecule high-throughput screen) to evaluate over 100,000 molecules in search of compounds that can be used to expand HSCs in UCB samples. If successful, we will be able to improve the medical options and healthcare of thousands of individuals, both in California and elsewhere. In addition, molecules that expand hematopoietic stem cells may have value in expanding other stem cells that could be used to treat other diseases, and they could help us understand the underlying biology of how stem cell expansion is controlled. This proposal brings together and leverages experts from industry (GE Healthcare) and academia (UCSF) to achieve our ambitious goals. In addition to improving the lives of citizens of California, the proposed project could have significant economic benefit as it fits nicely into the growing stem cell economic engine of the state.
Axina picta Schenkling 1907
Creators: name: Opitz, Weston
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cleridae
Axina
Axina picta

description: Axina picta Schenkling, 1907
Figures 71, 103.
Axina picta Schenkling, 1907: 309. Lectotype. Female. Here selected. Type locality: Amazon, Bates (Brasil) (BMNH). Paralectotype. 1 specimen. Brazil: Estado do Amazonas, Amazon, collection date not noted, Bates (SDEI). Corporaal 1950: 98. There is indication that Schenkling examined more than one specimen in his description of this species, but
he did not select a holotype, therefore, I invoke Recommendation 73F of the ICZN (1999) and designate a lectotype for this nominal species.
Diagnosis. The floricolorous marking on the elytron disc (Fig. 103) will distinguish the members of this species from congeners.
Redescription. Size. Length 12.0 mm; width 3.0 mm. Form. As in Fig. 103. Color. Cranium castaneous; antenna testaceous; prothorax bicolorous, venter flavotestaceous; pronotal sides and pronotal arch black, pronotum middle widely testaceous, testaceous area flows into subapical depression; pterothorax light castaneous; elytra bicolorous, X-like testaceous making that extends along sutural margin to elytral anterior margin, remainder of elytra dark brown, except elytral apical ¼ testaceous; legs dark mostly dark brown castaneous, except basal region of femora testaceous; abdomen testaceous. Head. Cranium finely punctate, frons about as wide as length of antennal pedicel; EW/FW 65/11. Thorax. Pronotum finely punctate, with 2 tumescences, concave at middle; PW/PL 130/170; elytra, asetiferous punctures not striate, punctures extend to elytral apical 3/4, interstitial spaces very wide; EL/EW 490/110. Abdomen. Pygidium securiform.
Distribution (for map see Fig. 71). This species is known from Brazil.
description: Published as part of Opitz, Weston, 2020, Taxonomic revision of the Western Hemisphere checkered beetle genus Axina Kirby (Coleoptera: Cleridae: Clerinae), pp. 1-70 in Insecta Mundi 2020 (793) on pages 27-28, DOI: 10.5281/zenodo.4564947
Childhood abuse and physiological dysregulation in midlife and old age
Creators: name: Lee, Chioun
Publisher: name: No Publisher Supplied
Year: 2012

description: The overarching goal of my research is to incorporate sociological perspectives (the life course perspective, inequality theory) with biomedical knowledge (stress theory) to document midlife and old age health for victims of childhood abuse. Using data from the National Survey of Midlife Development in the U.S. (MIDUS), I explore the extent to which childhood abuse creates physiological dysregulation and chronic diseases: cortisol abnormality (Chapter 2), metabolic syndrome (MetS) (Chapter 3), elevated markers of inflammation (Chapter 4), and three immune-related disorders (asthma, allergies, arthritis) (Chapter 2). I then explore the extent to which these associations are explained by three potential mediators: behavioral risk factors (sleeping and eating problems, body mass index [BMI]), perceived stress, and social relationship quality (Chapters 3-4). I also investigate whether profiles of childhood abuse and the pathways linking abuse to MetS differ by gender (Chapter 3). Finally, I assess whether the effects of childhood abuse on inflammatory markers vary by age group (Chapter 4).   I find five distinct classes of childhood abuse for the full sample and for women and four for men. Women are more likely than men to report frequent emotional and sexual abuse. Childhood abuse is associated with low cortisol levels and immune-related disorders. Low levels of cortisol partially mediate the association between abuse and both allergies and arthritis. Some abuse subgroups are at greater risk of MetS than the no abuse subgroup. For women, frequent sexual abuse increases the risk of MetS; this association is not statistically significant among men. The associations between abuse and inflammatory markers vary by age. In the younger age groups (ages 34-44 and 45-54), the levels of inflammatory markers for victims are higher than non-victims; there are no statistically significant differences in the older age groups (ages 55-64 and 65-84). Victims are at greater risk of mortality, suggesting that selective mortality might contribute to the reduced gap in the older age cohorts. High BMI, sleep problems, and weak or strained family ties partially mediate the association. Overall, my project demonstrates how integrating sociological perspectives and biomedical knowledge illuminates the associations between early life adversity and lifelong health consequences.
Cirrospilus lyncus Walker
Creators: name: Yefremova, Zoya A.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy

description: 6. Cirrospilus lyncus Walker
Material examined. None.
Hosts. Ectoparasitoid of Gracillariidae, Nepticulidae and Tischeriidae (Lepidoptera) (Bouček & Askew 1968). Distribution. Israel (Bouček & Askew 1968; Sternlicht 1968), and as Cirrospilus sp. near lyncus Walker by Argov and Rössler (1996). Widely distributed in the Palearctic (Askew & Shaw 1974; Yefremova 2002).
description: Published as part of Yefremova, Zoya A., 2015, An annotated checklist of the Eulophidae (excl. Tetrastichinae) (Hymenoptera: Chalcidoidea) of Israel, pp. 1-36 in Zootaxa 3957 (1) on page 5, DOI: 10.11646/zootaxa.3957.1.1, http://zenodo.org/record/288546
The mental timeline in discourse organization and processing
Creators: name: Lee, Choonkyu
Publisher: name: No Publisher Supplied
Year: 2012

description: Early language research has revealed important insights into the building blocksof language, such as morphosyntactic features and rules and truth-conditions of sentences. Once we situate language in real-life use, however, a wide range of factors come into play. Language interacts not only with the surrounding linguistic context but also with the situational context, our mental representation of content, and our background knowledge. The discourse-level interaction among linguistic and extralinguistic factors is relevant to both sides of the communication – the speaker, in choosing and organizing linguistic expressions, and the listener, in selecting among different possible structures and meanings for the linguistic input. The question I address in this dissertation is ‘how we keep track of time when we use language.’ My specific interests are (1) whether story time in narrative discourse is one of the critical dimensions that are dynamically updated as discourse progresses, and 2) how fine-grained our time representation is for discourse – whether it is simply an ordering of temporal points and intervals for the events and states described in thediscourse, or a timeline where duration is preserved in greater detail. In order to elaborate on these issues, I discuss results from my narrative production experiment and my narrative comprehension experiment. In the production study, based on wordless picture books, two kinds of linguistic expressions were found much more frequently after longer intervals in story time compared to shorter intervals: (1) explicit temporal marking with lexical or phrasal markers of topic time (e.g., when, the next morning, etc.); and (2) proper names in referring back to previously mentioned characters. In the comprehension study, based on short “two-minute mysteries,” longer duration in temporal adverbials in the stories tended to lead to longer reading times. I conclude that magnitudes such as duration in story content are preserved in our linguistic encoding and have observable impact on our linguistic decoding, and extend the situation-model framework of discourse comprehension (van Dijk & Kintsch, 1983; Zwaan, 1999) to discourse production. My findings thus support an account of communication as alignment of situation models (Pickering & Garrod, 2006).
Continuous Process for High Recovery Inland Desalination
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Advances in reverse osmosis (RO) technology over the past three decades have led to a significant reduction in the production cost of water desalination. Brackish water desalination, however, is often challenging because of the high costs associated with residual RO concentrate management, especially at inland locations. The integration of intermediate concentrate demineralization (ICD) with RO has recently been shown to be promising for concentrate minimization in a variety of brackish water desalting applications. In the proposed project, a primary RO (PRO) step desalts the brackish source water up to a water recovery level just below the threshold of membrane mineral scaling. Mineral scale precursors are subsequently removed from the PRO concentrate in an ICD step, where sparingly soluble mineral salts are precipitated and are subsequently removed via solids–liquid separation (e.g., sedimentation and filtration). The ICD step lowers the mineral scaling propensity of the PRO concentrate, thereby enabling additional product water recovery from the PRO concentrate in a subsequent secondary RO (SRO) desalting step and reducing the final volume of the residual SRO concentrate waste. We have develop the above approach, which was laboratory demonstrated, as a patent-pending two-step chemically-enhanced seeded precipitation (CESP) process for accelerated desupersaturation of antiscalant-containing, RO concentrate. In the CESP process, calcium carbonate precipitation is first induced via lime dosing for antiscalant scavenging, followed by subsequent calcium sulfate precipitation via gypsum seeding for concentrate desupersaturation with solids recycling to increase demineralization efficiency. The CESP process allows attaining high recovery desalting, while avoiding the crippling problem of mineral scaling. However, in order to proceed toward commercialization, there is a need to develop and demonstrate a pilot system in a continuous field operation of the CESP process integrated with RO desalting. A continuous CESP system and its field demonstration are imperative in order to provide convincing evidence of field performance to potential interested parties and spur interests for existing companies and/or investors for commercial development of the industrial-scale CESP process.
Axina piperata Opitz 2020, new species
Creators: name: Opitz, Weston
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cleridae
Axina
Axina piperata

description: Axina piperata Opitz, new species
Figures 62, 73, 104.
Type material. Holotype. Female. Type locality: S. Antonio da Barra, Pr. De Bahia, 11-XII-1888, Gounelle (Brazil) (MNHN).
Diagnosis. The encircled brown asetiferous punctures, which are diffused throughout the elytral disc against a pale ground color, will distinguish the holotype specimen from those of congener species.
Description. Size. Length 10.0 mm; width 2.5 mm. Form. As in Fig. 104. Color. Cranium brown; antenna testaceous; prothorax bicolorous, mostly brown, with pale streaks in middle of disc; pterothorax brown; elytra bicolorous, mostly flavotestaceous, with light brown tinge at humerus, elytron middle, and near elytral apex; asetiferous punctures encircled in brown; legs bicolorous, distal ½ of femora and proximal ½ of tibiae brown, remainder of legs flavotestaceous; abdomen flavotestaceous. Head. Cranium finely punctate, frons about as wide as length of antennal pedicel; EW/FW 50/15. Thorax. Pronotum finely punctate, with 2 paralateral spheroid tumescences, disc narrowly concave near middle; PW/PL 110/160; elytra, asetiferous punctures scattered, punctures extend posteriorly to elytral 3/4, interstitial spaces very wide; EL/EW 440/90. Abdomen. Female pygidium with a reflexed flap (Fig. 62).
Distribution (for map see Fig. 73). This species is known from Brazil.
Etymology. The specific epithet, piperata, is a Latin name that stems from piper (= pepper). I refer to the sprinkled-like appearance of the brown elytral asetiferous punctures.
description: Published as part of Opitz, Weston, 2020, Taxonomic revision of the Western Hemisphere checkered beetle genus Axina Kirby (Coleoptera: Cleridae: Clerinae), pp. 1-70 in Insecta Mundi 2020 (793) on page 28, DOI: 10.5281/zenodo.4564947
Reaction pathways linking chemisorption to desorption ofmethylchlorosilanes on copper(001)
Creators: name: Lallo, James
Publisher: name: No Publisher Supplied
Year: 2012

description: The interactions of silane molecules with metal surfaces are pivotal in many commercial  processes. Of particular interest is the commercial Direct Process," in which methyl  chloride (CH3Cl) is exposed to silicon, in the presence of a copper catalyst and other  promoters, producing dimethyldichlorosilane as the predominant product. Previous  UHV studies have investigated the interaction of pre-dissociated" methyl (CH3) and  chlorine (Cl) with copper and copper-silicide surfaces. This thesis investigates the reac-  tion mechanisms of pre-associated" methylchlorosilanes ((CH3)xClySiHz, x+y+z=4)  adsorbed on a copper(001) surface. The goal was to develop an understanding of the  intermediates and transfer processes involved for dissociative adsorption and subse-  quent desorption of these molecules. Only molecules containing at least one Si-H bond  were observed to undergo chemisorption. It was found that dimethylsilane (CH3)2SiH2  and methylsilane (CH3)SiH3 exhibit ligand transfer on the copper surface, leading to  the desorption of trimethylsilane (CH3)3SiH, in both cases. The suggested intermedi-  ates present after adsorption of methylsilane were methylsilyl CH3SiH2, methysilylene  ii  CH3SiH and methylsilylidyne CH3Si. The proposed mechanisms leading to trimethylsi-  lane desorption involve rate liming methyl transfer between silicon centers. Chlorinated  silane species also exhibited methyl transfer to form desorbing silane species. While  methyl transfer appears facile, chlorine transfer among silicon centers was not observed.  Investigations were also conducted on absorbed methyl groups alone on the copper sur-  face. Under certain conditions of azomethane pyrolysis the adsorption of both CH3  groups and H atoms on the copper surface was observed. The co-adsorption of methyl  and atomic hydrogen leads to the simultaneous desorption of methane and molecular  hydrogen at  300K. Any remaining methyl groups decompose at 420K, leading to a  resumption of the simultaneous methane and H2 desorption. The relative intensities  and peak desorption temperatures of the CH4 and H2 desorption were used to study  the kinetics of the associative desorption reaction.
Characterization of pharmaceutical bilayer tablets
Creators: name: Kottala, Niranjan K.
Publisher: name: No Publisher Supplied
Year: 2012

description: Bilayer tablets are generating great interest recently in the pharmaceutical industry as they offer several advantages over conventional single layer tablets. However, the production of bilayer tablets has been facing great difficulties as the layered tablets are prone to delaminate at the interface and fracture in the individual layers due to insufficient bonding strength. Poor product performance is a cause of great concern as it will incur financial loses and regulatory liabilities. In the pharmaceutical industry the process of bilayer design has been heavily dependent on the trial-and-error approach during the formulation and process development stages. To overcome this hurdle it is critical to understand the mechanical properties of the materials and to develop a methodology for the characterization of bilayer tablets.     The work presented in this dissertation will focus on gaining the mechanistic understanding on the factors that impact the performance of the bilayer tablets. A methodology has been developed based on the principles of fracture mechanics for the characterization of bilayer tablets. As part of this endeavor, interfacial stress intensity was estimated. To understand the impact of manufacturing process parameters and environmental conditions on the bonding strength of bilayer tablets a comprehensive DOE has been executed to obtain statistical trends.     Results indicated that material properties, compaction forces of the layers and interfacial topography have a strong influence on the strength of bilayer tablets. Strength of bilayer tablets increased with the increase of interfacial roughness and curvature. Physico-mechanical properties of the powders, deformation histories of the layers, and compression process parameters greatly influenced the interfacial stress intensity factor of the bilayer tablets. For the bilayer tablets made with plastic material in the first layer, the stress intensity factor is more dependent on interfacial radius of curvature than on interfacial roughness and vice versa in the case of bilayer tablets made with brittle material in the first layer.      The mechanistic understanding and the methodology developed for the characterization of the bilayer tablets in this dissertation will enable to move away from the existing “trial-and-error” approach during the design and development of bilayer tablets. The new paradigm of bilayer tablet development will incorporate the principles of the quality by design by leveraging the prior knowledge.