cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Equination (inoculation of horsepox): An early alternative to vaccination (inoculation of cowpox) and the potential role of horsepox virus in the origin of the smallpox vaccine
Creators: name: Esparza, José
name: Schrick, Livia
name: Damaso, Clarissa R.
name: Nitsche, Andreas
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2017
Subjects: subject: History
subject: Vaccination
subject: Smallpox
subject: Cowpox
subject: Horsepox
subject: Jenner
subject: Vaccinia
subject: Variola
subject: 610 Medizin

description: For almost 150 years after Edward Jenner had published the “Inquiry” in 1798, it was generally assumed that the cowpox virus was the vaccine against smallpox. It was not until 1939 when it was shown that vaccinia, the smallpox vaccine virus, was serologically related but different from the cowpox virus. In the absence of a known natural host, vaccinia has been considered to be a laboratory virus that may have originated from mutational or recombinational events involving cowpox virus, variola viruses or some unknown ancestral Orthopoxvirus. A favorite candidate for a vaccinia ancestor has been the horsepox virus. Edward Jenner himself suspected that cowpox derived from horsepox and he also believed that “matter” obtained from either disease could be used as preventative of smallpox. During the 19th century, inoculation with cowpox (vaccination) was used in Europe alongside with inoculation with horsepox (equination) to prevent smallpox. Vaccine-manufacturing practices during the 19th century may have resulted in the use of virus mixtures, leading to different genetic modifications that resulted in present-day vaccinia strains. Horsepox, a disease previously reported only in Europe, has been disappearing on that continent since the beginning of the 20th century and now seems to have become extinct, although the virus perhaps remains circulating in an unknown reservoir. Genomic sequencing of a horsepox virus isolated in Mongolia in 1976 indicated that, while closely related to vaccinia, this horsepox virus contained additional, potentially ancestral sequences absent in vaccinia. Recent genetic analyses of extant vaccinia viruses have revealed that some strains contain ancestral horsepox virus genes or are phylogenetically related to horsepox virus. We have recently reported that a commercially produced smallpox vaccine, manufactured in the United States in 1902, is genetically highly similar to horsepox virus, providing a missing link in this 200-year-old mystery.
Regionale Unterschiede in der Prävalenz von kardiovaskulären Risikofaktoren bei Männern und Frauen in Deutschland
Creators: name: Diederichs, Claudia
name: Neuhauser, Hannelore
name: Kroll, Lars Eric
name: Lange, Cornelia
name: Mensink, Gert
name: Dornquast, Christina
name: Heidemann, Christin
name: Scheidt-Nave, Christa
name: Busch, Markus
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2016
Subjects: subject: Risikofaktoren
subject: Hypertonie
subject: Diabetes
subject: Regionale Unterschiede
subject: Kardiovaskuläre Erkrankungen
subject: 610 Medizin

description: Hintergrund: Über die Hälfte aller kardiovaskulären Erkrankungen wird von acht zum Teil vermeidbaren Risikofaktoren verursacht. Ziele: Angesichts deutlicher Prävalenz- und Mortalitätsunterschiede bei Herz-Kreislauf-Erkrankungen zwischen den deutschen Bundesländern wird die regionale Verteilung von kardiovaskulären Risikofaktoren bevölkerungsrepräsentativ und geschlechtsspezifisch untersucht. Methoden: Anhand von gepoolten Daten (n = 62.606) der bundesweiten, telefonischen Gesundheitssurveys „Gesundheit in Deutschland aktuell (GEDA)“ 2009, 2010 und 2012 wurden die Prävalenz von sportlicher Inaktivität, riskantem Alkoholkonsum, Rauchen, geringem Obst- und Gemüseverzehr, Adipositas, ärztlich diagnostizierter Hypertonie, Diabetes und Fettstoffwechselstörungen sowie die zusammengefasste Anzahl von Risikofaktoren getrennt für Männer und Frauen in den Bundesländern bestimmt. Zusätzlich wurde der Einfluss von Alter und Sozialstatus auf Prävalenzunterschiede untersucht. Ergebnisse: Im Bundesdurchschnitt hatten 36,0 % der männlichen und 26,6 % der weiblichen Bevölkerung drei oder mehr Risikofaktoren. Große Unterschiede zwischen Männern und Frauen gab es vor allem beim riskanten Alkoholkonsum (32,8 % versus 21,7 %), einem geringen Obst- und Gemüseverzehr (20,6 % versus 10,4 %) sowie beim aktuellen Rauchen (32,6 % versus 24,9 %). Bei allen acht Risikofaktoren wurden deutliche Prävalenzunterschiede zwischen den Bundesländern gefunden. In den ostdeutschen Bundesländern mit Ausnahme von Berlin wurden die höchsten Prävalenzen von sportlicher Inaktivität, Adipositas, Hypertonie und Diabetes bei beiden Geschlechtern und von riskantem Alkoholkonsum bei Männern beobachtet. Sachsen-Anhalt war das einzige Bundesland mit den höchsten Prävalenzen für zwei Risikofaktoren. Beim Rauchen nahmen die drei Stadtstaaten Berlin, Hamburg und Bremen vordere Rangplätze ein. Der Anteil der Bevölkerung mit weniger als einer Portion Obst, Gemüse oder Saft pro Tag war geschlechtsübergreifend im Saarland am höchsten. Die regionalen Unterschiede blieben auch nach Adjustierung für Alter und sozialen Status bestehen. Diskussion: Die Verteilung der Risikofaktoren zwischen den Bundesländern zeigt ähnliche regionale Unterschiede wie die Prävalenz und Mortalität von Herz-Kreislauf-Erkrankungen mit einer ungünstigeren Situation in den ostdeutschen Ländern mit Ausnahme von Berlin. Insgesamt ist für ganz Deutschland ein erheblicher Bedarf hinsichtlich der Prävention von größtenteils modifizierbaren Risikofaktoren für Herz-Kreislauf-Erkrankungen bei Männern und Frauen erkennbar.
Additional file 1 of Comparative effectiveness of hyaluronic acid, platelet-rich plasma, and platelet-rich fibrin in treating temporomandibular disorders: a systematic review and network meta-analysis
Creators: name: Xu, Jingjing
name: Ren, Hui
name: Zhao, Shuwei
name: Li, Qian
name: Li, Ce
name: Bao, Guangjie
name: Kang, Hong
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Search strategy.
Transient Response of Tapered and Angled Injectors Subjected to a Passing Detonation Wave
Creators: name: Celebi, Hasan Fatih
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Aerospace engineering not elsewhere classified

description: A total number of 849 tests were conducted to investigate the transient response of liquid injectors with various geometries including different taper angles, injection angles and orifice lengths. High-speed videos were analyzed to characterize refill times and back-flow distances of nine different injector geometries subjected to a ethylene-oxygen detonation wave. Water was used as the working fluid and experiments were performed at two different vessel pressure settings (60 and 100 psia). Although a minimal difference was found between plain and angled injectors due to having constant orifice diameter geometry, introduction of taper angle resulted in more agile injectors with less sensitivity to ambient and feed pressures. Several attempts were made to normalize refill times and obtain a general trend for transient response of liquid injectors.
The impact of the triglyceride-glucose index on the deterioration of kidney function in patients with cardiovascular-kidney-metabolic syndrome: insight from a large cohort study in China
Creators: name: Shang, Zhi
name: Feng, Song-Tao
name: Qian, Hui
name: Deng, Zhen-Ling
name: Wang, Yue
name: Gao, Yue-Ming
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Marine Biology
Hematology

description: The triglyceride-glucose (TyG) index has emerged as a credible surrogate indicator of insulin resistance in recent years. This study aimed to investigate the relationship between the TyG index and the deterioration of kidney function in patients with cardiovascular-kidney-metabolic (CKM) syndrome. In this retrospective cohort study from China, 27,407 hospitalized patients with stage 1–4 CKM syndrome were consecutively included. The participants were categorized into four groups according to TyG index quartiles. The study outcome was the deterioration of kidney function, defined as a decrease in estimated glomerular filtration rate (eGFR) ≥ 40% from baseline. Restricted cubic spline (RCS) curves and multivariate Cox analysis were used for analysis. 3,248 outcome events were recorded during a mean follow-up period of 34 months. The RCS plot displayed a U-shaped curve between the baseline TyG index and the deterioration of kidney function (P for non-linear < 0.001). The baseline TyG index with the lowest hazard ratio (HR) of eGFR decline ranges from 8.65 to 9.15, with an inflection point at 8.88. After fully adjusting for covariates, HRs and 95% confidence intervals (CIs) from the lowest to highest TyG index quartile were 1.00 (reference), 0.82 (0.74, 0.91), 0.78 (0.70, 0.86), and 0.93 (0.83, 1.03), respectively. According to the Kaplan-Meier survival curve, the risk of deterioration of kidney function was elevated in the lowest and highest TyG index quartiles (log-rank test, p < 0.0001). In individuals with CKM syndrome, a non-linear U-shaped relationship existed between the baseline TyG index and the deterioration of kidney function.
Asynchronous Parallel Algorithms for Big-Data Nonconvex Optimization
Creators: name: Cannelli, Loris
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Automation engineering
Control engineering

description: The focus of this Dissertation is to provide a unified and efficient solution method for an important class of nonconvex, nonsmooth, constrained optimization problems. Specifically, we are interested in problems where the objective function can be written as the sum of a smooth, nonconvex term, plus a convex, but possibly nonsmooth, regularizer. It is also considered the presence of nonconvex constraints. This kind of structure arises in many large-scale applications, as diverse as information processing, genomics, machine learning, or imaging reconstruction. We design the first parallel, asynchronous, algorithmic framework with convergence guarantees to stationary points of the class of problems under exam. The method we propose is based on Successive Convex Approximation techniques; it can be implemented with both fixed and diminishing stepsizes; and enjoys sublinear convergence rate in the general nonconvex case, and linear convergence case under strong convexity or under less stringent standard error bound conditions. The algorithmic framework we propose is very abstract and general and can be applied to different computing architectures (e.g., message-passing systems, cluster of computers, shared-memory environments), always converging under the same set of assumptions. In the last Chapter we consider the case of distributed multi-agent systems. Indeed, in many practical applications the objective function has a favorable separable structure. In this case, we generalize our framework to take into consideration the presence of different agents, where each one of them knows only a portion of the overall function, which they want cooperatively to minimize. The result is the first fully decentralized asynchronous method for the setting described above. The proposed method achieve sublinear convergence rate in the general case, and linear convergence rate under standard error bound conditions. Extensive simulation results on problems of practical interest (MRI reconstruction, LASSO, matrix completion) show that the proposed methods compare favorably to state-of-the art-schemes.
Endothelial injury is one of the risk factors for the progression of vascular calcification in patients receiving maintenance dialysis
Creators: name: Yao, Dan-Dan
name: Yan, Xiao-Wei
name: Zhou, Yan
name: Li, Zuo-Lin
name: Qiu, Fang-Xin
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Statistics
subject: FOS: Mathematics
subject: Virology
subject: Computational Biology

description: Vascular calcification is common and progressive in patients with chronic kidney disease. However, the risk factors associated with the progression of vascular calcification in patients receiving maintenance dialysis have not been fully elucidated. Here, we aimed to evaluate vascular calcification and identify the factors associated with its progression in patients receiving maintenance hemodialysis. This is a prospective longitudinal study that included 374 patients receiving maintenance hemodialysis. The participants received assessments of coronary artery calcification (CAC) and abdominal aortic calcification (AAC), as measured by computed tomography. After the baseline investigation, a 2 years follow-up was performed. We also detected the markers of endothelial injury [E-selectin and soluble intercellular adhesion molecule-1 (sICAM-1)]. Finally, the risk factors affecting the CAC and AAC progression were examined by multivariate logistic regression analysis. Among 374 patients, the median [interquartile range (IQR)] age was 54.0 (40.0–62.0) years; 59.9% of patients were male. The median (IQR) follow-up time was 1.9 (1.8–2.0) years for all patients. By the end of 2-year follow-up, progression of vascular calcification (including CAC and AAC) was observed in 58.0% of patients. Further, compared with the patients without progression of vascular calcification, the endothelial injury (including E-selectin and sICAM-1) of patients with progression of vascular calcification was markedly enhanced. Moreover, after adjustment for the confounders, endothelial injury was a risk factor for the progression of vascular calcification. The present study indicated that endothelial injury is one of the risk factors for the progression of vascular calcification in patients receiving maintenance hemodialysis.
Passive Vibration Mitigation Via Mechanical Nonlinear Bistable Oscillators
Creators: name: Grantz, Christian Bjorn
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified

description: Passive vibration mitigation via multi-stable, mechanical means is relatively unexplored. In addition, achieving vibration suppression through avoiding resonance is at the forefront of up and coming research. This thesis investigates the application of a purely mechanical, bistable device as a passive method of vibration suppression. A purely mechanical device does not require power, multiple materials, or electrical circuits, and a passive device does not require external interaction or control. Therefore, a passive, mechanical device could be implemented with ease even in physically constrained environments with large dynamic loads, such as turbomachinery. The purely mechanical, bistable device presented herein replicates the two switches per resonance crossing evident in semi-active Resonance Frequency Detuning method. This work explores two different bistable, mass-spring models. The first is a single degree of freedom nonlinear mass spring model aiming to utilize asymmetry in the potential function to change the stiffness of the overall system. The second model is a coupled, two degree of freedom system that combines the nonlinear softening and hardening spring characteristics with the unique stiffnesses of two stable states. The performance is verified by targeting the first mode of a cantilever beam, with the device shifting the resonance away from the excitation frequency. Future research could apply these idealized models to complex, rotating structures and replicate the performance of the passive, mechanical devices in a physical geometry that could be manufactured as a part of a target structure.
ZAMONAVIY KOMPYUTERLAR BO'LIMINI O'QITISH METODIKASI
Creators: name: Xurramova, Sarvinoz
Publisher: name: Zenodo
Year: 2025

description: Ushbu maqolada zamonaviy kompyuterlar bo‘limini o‘qitish metodikasi tahlil qilinadi. Kompyuter fanlarini o‘qitishda innovatsion yondashuvlar, interfaol metodlar, virtual laboratoriyalar va gamifikatsiya texnologiyalaridan foydalanishning samaradorligi ko‘rib chiqiladi. Shuningdek, loyiha asosida ta’lim berish va raqamli texnologiyalar orqali o‘quvchilarning bilim olish jarayonini optimallashtirish masalalari muhokama qilinadi.
Monetary Policy and Heterogeneous Labor Markets
Creators: name: Chaudhuri, Pritha
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Macroeconomics (incl. monetary and fiscal theory)
Other economics not elsewhere classified

description: Labor market indicators such as unemployment and labor force participation show a significant amount of heterogeneity across demographic groups, which is often not incorporated in monetary policy analysis. This dissertation is composed of three essays that explore the effect of labor market heterogeneity on the design and conduct of monetary policy. The first chapter, Effect of Monetary Policy Shocks on Labor Market Outcomes, studies this question empirically by looking at dynamics of macroeconomic outcomes to a monetary policy shock. I construct a measure of monetary policy shock using narrative methods that represent the unanticipatory changes in policy. Impulse response of unemployment rates for high and low-skill workers show low-skill workers bear a greater burden of contractionary monetary policy shock. Their unemployment rates increase by almost four times that of the high-skill group. Even though we see differences in dynamic response of unemployment rates, the empirical analysis shows some puzzling results where effects of contractionary shock are expansionary in nature. Moreover, these results are plagued by the “recursiveness assumption” that the shock does not affect current output and prices, which is at odds with theoretical models in the New Keynesian literature. In the second chapter, Skill Heterogeneity in an Estimated DSGE Model, I use a structural model to better identify these shocks and study dynamic responses of outcomes to economic shocks. I build a dynamic stochastic general equilibrium model, which captures skill heterogeneity in the U.S. labor market. I use Bayesian estimation techniques with data on unemployment and wages to obtain distribution of key parameters of the model. Low-skilled workers have a higher elasticity of labor supply and labor demand, contributing to the flatness of the wage Phillips curve estimated using aggregate data. A contractionary monetary policy shock has immediate effects on output and prices, lowering both output and inflation. Moreover, it increases unemployment rates for both high and low-skill groups, the magnitude being larger for the latter group. The presence of labor market heterogeneity will have new implications for the design of monetary policy, that I study in the third chapter, Optimal Monetary Policy with Skill Heterogeneity. I design an optimal policy for the central bank where policymakers respond to the different inflation-unemployment trade-off between high and low-skill workers. The monetary authority must strike a balance between stabilization of inflation, GDP and outcomes of high and low-skill workers separately. This optimal policy can be implemented by a simple interest rate rule with unemployment rates for high and low-skill workers and this policy is welfare improving.
Additional file 2 of Comparative effectiveness of hyaluronic acid, platelet-rich plasma, and platelet-rich fibrin in treating temporomandibular disorders: a systematic review and network meta-analysis
Creators: name: Xu, Jingjing
name: Ren, Hui
name: Zhao, Shuwei
name: Li, Qian
name: Li, Ce
name: Bao, Guangjie
name: Kang, Hong
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. The forest plot. (A) The forest plot about pain after one monthtreatment. (B) The forest plot about pain after three months treatment. (C) Theforest plot about pain after six months treatment. (D) The forest plot aboutMMO after one month treatment. (E) The forest plot about MMO after three monthstreatment. (F) The forest plot about MMO after six months treatment. HA:hyaluronic acid; PRP: platelet-rich plasma; PRF: platelet-rich fibrin; PO:placebo; MMO: maximal mouth opening.
Additional file 1 of The FLY-project: study protocol for mixed methods research to explore the complex social dynamics of sustainable food-related lifestyles in youth in practical education
Creators: name: van Etten, Soraya
name: Jansen, Lonneke
name: Bal, Michèlle
name: Dermody, Brian J.
name: Müller, Eggo
name: de Wit, John
name: Stok, Marijn
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Additional file 1.
Genetic insights into blood urea nitrogen as a risk factor for coronary artery disease: a Mendelian randomization study in East Asians
Creators: name: Shen, Lijuan
name: Zhang, Qianxin
name: Zhu, Zhouyang
name: Huang, Zhouqing
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Previous studies have reported the association between blood urea nitrogen (BUN) and cardiovascular diseases (CVDs) but the causality has not yet been proved. Our study aimed to assess the causal effect of BUN levels on several CVDs using the two-sample Mendelian randomization (MR) method. This is the first MR study examining causal relationships between BUN and multiple cardiovascular diseases. Using data from genome-wide association studies (GWAS) of East Asians, we identified single nucleotide polymorphisms (SNPs) associated with BUN levels as instrumental variables. Specifically, SNPs reaching genome-wide significance (p < 5 × 10−8) were selected from a large-scale BUN dataset comprising (n = 148,767). To ensure robustness, multiple MR methods, including MR-Egger, weighted median, inverse variance weighting (IVW), simple mode, and weighted mode, were employed to evaluate the causal relationship between BUN levels and CVDs. Sensitivity analyses were conducted to assess the reliability and stability of the results. The IVW approach showed that a higher level of BUN was associated with an increased risk of coronary artery disease (CAD) (OR = 1.42, 95% CI = 1.226 − 1.644, p = 2.89 × 10−6). For atrial fibrillation (OR = 0.868, 95% CI = 0.678 − 1.110, p = 0.258), arrhythmia (OR = 0.907, 95% CI = 0.777 − 1.059, p = 0.216), and congestive heart failure (OR = 0.924, 95% CI = 0.781 − 1.092, p = 0.353), no significant associations were found. Sensitivity analyses indicated the results were robust. This MR work shows that elevated BUN levels are a potential biomarker for CAD risk but lack causal associations with other CVDs. These findings suggest avenues for risk stratification and CAD prevention strategies, emphasizing the clinical utility of BUN monitoring in at-risk populations.
Exploring the foundations, implications, and discursive sense making of (employee-directed) corporate social responsibility (CSR)
Creators: name: Miller, Katharine E
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Communication studies
Organisational, interpersonal and intercultural communication

description: This study takes a mixed-method, micro-approach to understanding the internal sensemaking and understanding of employee-directed CSR given the potentially changing nature of such efforts. In particular, this study explores how organizational members (i.e., employees) construct knowledge (via their sensemaking) of organizational CSR and primarily those employee-focused.I take a communicative and discursive approach in viewing CSR as a socially constructed phenomenon (Schultz, Castello, & Morsing, 2013) and (social) movement within organizations (Georgallis, 2017), and thus contextual and unique to organizational sites. Findings revealed D/discourses of CSR from employee perceptions at the micro level and reflected in macro level document messaging. Through this, I found various paradoxes of CSR from the expectations versus reality of what it means for organizations to be “responsible.” At the individual level, employee sensemaking around CSR came to light—particularly in highlighting how these stakeholders rationalize, perceive, and identify with such efforts, especially those targeting or benefiting employees. In presenting a multi-method study, this dissertation contributes to research on the micro-foundations and limited internal perspective of CSR and provides important pragmatic implications given the timely and relevant nature of this work.
sj-pdf-1-lup-10.1177_09612033211031989 - Supplemental material for Predictive factors of fetal and maternal pregnancy outcomes in Japanese patients with systemic lupus erythematosus
Creators: name: Irino, Kensuke
name: Arinobu, Yojiro
name: Ayano, Masahiro
name: Kawano, Shotaro
name: Kimoto, Yasutaka
name: Mitoma, Hiroki
name: Akahoshi, Mitsuteru
name: Akashi, Koichi
name: Horiuchi, Takahiko
name: Niiro, Hiroaki
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-1-lup-10.1177_09612033211031989 for Predictive factors of fetal and maternal pregnancy outcomes in Japanese patients with systemic lupus erythematosus by Kensuke Irino, Yojiro Arinobu, Masahiro Ayano, Shotaro Kawano, Yasutaka Kimoto, Hiroki Mitoma, Mitsuteru Akahoshi, Koichi Akashi, Takahiko Horiuchi and Hiroaki Niiro in Lupus
sj-pdf-1-ajs-10.1177_03635465211025003 – Supplemental material for Neither Residual Anterior Knee Laxity Up to 6 mm nor a Pivot Glide Predict Patient-Reported Outcome Scores or Subsequent Knee Surgery Between 2 and 6 Years After ACL Reconstruction
Creators: name: Magnussen, Robert A.
name: Reinke, Emily K.
name: Huston, Laura J.
name: Briskin, Isaac
name: Cox, Charles L.
name: Dunn, Warren R.
name: Flanigan, David C.
name: Jones, Morgan H.
name: Kaeding, Christopher C.
name: Matava, Matthew J.
name: Parker, Richard D.
name: Smith, Matthew V.
name: Wright, Rick W.
name: Spindler, Kurt P.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-ajs-10.1177_03635465211025003 for Neither Residual Anterior Knee Laxity Up to 6 mm nor a Pivot Glide Predict Patient-Reported Outcome Scores or Subsequent Knee Surgery Between 2 and 6 Years After ACL Reconstruction by Robert A. Magnussen, Emily K. Reinke, Laura J. Huston, Isaac Briskin, Charles L. Cox, Warren R. Dunn, David C. Flanigan, Morgan H. Jones, Christopher C. Kaeding, Matthew J. Matava, Richard D. Parker, Matthew V. Smith, Rick W. Wright and Kurt P. Spindler in The American Journal of Sports Medicine
Connection Problem for Painlevé tau Functions
Creators: name: Prokhorov, Andrei
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mathematical physics not elsewhere classified
Integrable systems (classical and quantum)
Ordinary differential equations, difference equations and dynamical systems

description: We derive the differential identities for isomonodromic tau functions, describing their monodromy dependence. For Painlev\'e equations we obtain them from the relation of tau function to classical action which is a consequence of quasihomogeneity of corresponding Hamiltonians. We use these identities to solve the connection problem for generic solution of Painlev\'e-III(D8) equation, and homogeneous Painlev\'e-II equation. We formulate conjectures on Hamiltonian and symplectic structure of general iso\-mo\-no\-dro\-mic deformations we obtained during our studies and check them for Painlev\'e equations.
Global research trends and collaborations in acute kidney injury (AKI) and sepsis: a bibliometric analysis (2004–2024)
Creators: name: Yang, Yuru
name: Zhao, Shuang
name: Liu, Shuai
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Biological Sciences not elsewhere classified
Science Policy

description: Acute kidney injury (AKI) and sepsis are critical clinical conditions associated with high morbidity and mortality. Despite growing research interest, there remains a need for a comprehensive analysis of global research trends in this field. Bibliometric analysis offers a quantitative approach to assessing the evolution of scientific knowledge, collaborative networks, and emerging research areas over time. This study aims to map the global landscape of research on AKI and sepsis over the last two decades (2004–2024), identify major contributors, collaboration networks, key research trends, and highlight gaps in the literature. We conducted a bibliometric analysis of research articles from leading databases. The study utilized network visualization techniques to assess co-authorship, citation patterns, and keyword co-occurrence, focusing on the most influential countries, institutions, and research collaborations. Results reveal China leads in publication volume, yet countries like the United States and Australia show higher international collaboration rates and citation impact. Additionally, thematic analyses highlight critical research areas, including biomarkers, bioenergetics, inflammation, and machine learning, marking significant advancements in the understanding and management of AKI. This bibliometric analysis offers valuable insights into the evolving landscape of AKI and sepsis research, emphasizing the importance of collaborative efforts to address knowledge gaps and ensure evidence-based care across diverse healthcare settings. Future research should prioritize the development of biomarkers and the integration of AI-driven technologies to enhance early diagnosis and personalize treatment strategies for AKI patients.
sj-pdf-1-ica-10.1177_02762366211034402 - Supplemental material for Did Children Interact With Their Personified Objects During the COVID-19 Pandemic?
Creators: name: Yamaguchi, Masanori
name: Moriguchi, Yusuke
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-1-ica-10.1177_02762366211034402 for Did Children Interact With Their Personified Objects During the COVID-19 Pandemic? by Masanori Yamaguchi and Yusuke Moriguchi in Imagination, Cognition and Personality
SAFETY IMPLICATIONS OF ROADWAY DESIGN AND MANAGEMENT: NEW EVIDENCE AND INSIGHTS IN THE TRADITIONAL AND EMERGING (AUTONOMOUS VEHICLE) OPERATING ENVIRONMENTS
Creators: name: Chen, Sikai
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Transport engineering

description: In the context of highway safety factors, road geometrics and pavement condition are of particular interest to highway managers as they fall within their direct control and therefore can be addressed through highway projects. In spite of the preponderance of econometric modeling in highway safety research, there still remain areas worthy of further investigation. These include 1) the lack of sufficient feedback to roadway preservation engineers regarding the impacts of road-surface condition on safety; 2) the inadequate feedback to roadway designers on optimal lane and shoulder width allocation; 3) the need for higher predictive capability and reliability of models that analyze roadway operations; and 4) the lack of realistic simulations to facilitate reliable safety impact studies regarding autonomous vehicles (AV). In an attempt to contribute to the existing knowledge in this domain and to throw more light on these issues, this dissertation proposes a novel framework for enhanced prediction of highway safety that incorporates machine learning and econometrics with optimization to evaluate and quantify the impacts of safety factors. In the traditional highway operating environment, the proposed framework is expected to help agencies improve their safety analysis. Using an Indiana crash dataset, this dissertation implements the framework, thereby 1) estimating the safety impacts of the road-surface condition with advanced econometric specifications, 2) optimizing space resource allocations across highway cross-sectional elements, and 3) predicting the fatality status of highway segments using machine learning algorithms. In addition, this dissertation discusses the opportunities and the expected safety impacts and benefits of AV in the emerging operating environment. The dissertation also presents a proposed deep learning-based autonomous driving simulation framework that addresses the limitations of AV testing and evaluation on in-service roads and test tracks.
sj-pdf-1-tra-10.1177_14604086211033083 – Supplemental Material for Prevalence and predictors of return to work following a spinal cord injury using a work disability prevention approach: A systematic review and meta-analysis
Creators: name: Nowrouzi-Kia, Behdin
name: Nadesar, Nirusa
name: Sun, Yingji
name: Ott, Markus
name: Sithamparanathan, Gobika
name: Thakkar, Priya
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine

description: Supplemental Material, sj-pdf-1-tra-10.1177_14604086211033083 for Prevalence and predictors of return to work following a spinal cord injury using a work disability prevention approach: A systematic review and meta-analysis by Behdin Nowrouzi-Kia, Nirusa Nadesar, Yingji Sun, Markus Ott, Gobika Sithamparanathan and Priya Thakkar in Trauma
sj-pdf-1-pps-10.1177_1745691621991864 – Supplemental material for The Neuroscientification of Psychology: The Rising Prevalence of Neuroscientific Concepts in Psychology From 1965 to 2016
Creators: name: Haslam, Nick
name: Vylomova, Ekaterina
name: Murphy, Sean C.
name: Wilson, Sarah J.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, sj-pdf-1-pps-10.1177_1745691621991864 for The Neuroscientification of Psychology: The Rising Prevalence of Neuroscientific Concepts in Psychology From 1965 to 2016 by Nick Haslam, Ekaterina Vylomova, Sean C. Murphy and Sarah J. Wilson in Perspectives on Psychological Science
Additional file 3 of Comparative effectiveness of hyaluronic acid, platelet-rich plasma, and platelet-rich fibrin in treating temporomandibular disorders: a systematic review and network meta-analysis
Creators: name: Xu, Jingjing
name: Ren, Hui
name: Zhao, Shuwei
name: Li, Qian
name: Li, Ce
name: Bao, Guangjie
name: Kang, Hong
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3. The funnel plot. (A) The funnel plot about pain after one month,three months and six months treatment. (B) The funnel plot about MMO after onemonth, three months and six months treatment. MMO: maximal mouth opening.
sj-pdf-1-sci-10.1177_00368504211024113 – Supplemental material for An optimal non-viral gene transfer method for genetically modifying porcine bone marrow-derived endothelial progenitor cells for experimental therapeutics
Creators: name: Zhang, Qiuwang
name: Wang, Chenxi
name: Cheema, Zayed M
name: Kutryk, Michael JB
Publisher: name: SAGE Journals
Year: 2021
Subjects: Biological Sciences not elsewhere classified

description: Supplemental material, sj-pdf-1-sci-10.1177_00368504211024113 for An optimal non-viral gene transfer method for genetically modifying porcine bone marrow-derived endothelial progenitor cells for experimental therapeutics by Qiuwang Zhang, Chenxi Wang, Zayed M Cheema and Michael JB Kutryk in Science Progress
Causal insights into major risk factors for diabetic kidney disease: a comprehensive meta-analysis and Mendelian randomization study
Creators: name: Zhou, Yucong
name: Liu, Yahong
name: Wu, Liang
name: Zhang, Yucai
name: Wen, Huixin
name: Hu, Jiangwei
name: Huo, Zhenxia
name: Ju, Shuyuan
name: Sheng, Ruizheng
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: This study aims to identify major risk factors for diabetic kidney disease (DKD) and examine their causal relationships using meta-analysis and Mendelian randomization. This study reviewed diabetic nephropathy literature up to September 2024, evaluating quality with NOS, AMSTAR 2, and JBI. It analyzed heterogeneity using the Baujat plot and leave-one-out method, and conducted meta-analysis with fixed- or random-effects models based on I2. Publication bias was assessed with a funnel plot and Egger’s test. Mendelian randomization using GWAS SNPs explored causal links through IVW, MR-Egger, weighted median, and weighted mode, while pleiotropy and heterogeneity were checked with the MR-Egger intercept and Cochran’s Q. Meta-analysis identified several significant risk factors for DKD, including hypertension (relative risk [RR] = 6.33), comorbidities (RR = 4.96), poor glycemic control (RR = 3.27), non-adherence to treatment (RR = 3.30), an unhealthy diet (RR = 5.96), physical inactivity (RR = 5.60), and hyperuricemia (RR = 5.24). MR analysis further confirmed a causal relationship between high carbohydrate intake (odds ratio [OR] = 1.393, p = 0.043) and increased DKD risk, while vegetable consumption (OR = 0.816, p = 0.011) was identified as a protective factor. These findings reinforce the critical role of dietary and lifestyle interventions in DKD prevention. By integrating meta-analysis with Mendelian randomization, this study provides robust evidence linking modifiable risk factors, particularly dietary habits and lifestyle behaviors, to DKD development. The findings highlight the need for early preventive strategies targeting glycemic control, hypertension, and dietary modifications to mitigate DKD progression.
Supplemental Material, sj-pdf-1-ear-10.1177_01455613211028086 - Multiple Warthin Tumors With Epithelial–Myoepithelial Carcinoma of the Ipsilateral Parotid Gland: A Case Report
Creators: name: Sha, Tong
name: Yu, Yang
name: Liu, Kang
name: Sun, Bin
name: Zhang, Wei
Publisher: name: SAGE Journals
Year: 2021
Subjects: Otorhinolaryngology

description: Supplemental Material, sj-pdf-1-ear-10.1177_01455613211028086 for Multiple Warthin Tumors With Epithelial–Myoepithelial Carcinoma of the Ipsilateral Parotid Gland: A Case Report by Tong Sha, Yang Yu, Kang Liu, Bin Sun and Wei Zhang in Ear, Nose & Throat Journal
Modeling the Impacts of Changes in Soil Microbes and Mosses on Arctic Terrestrial Ecosystem Carbon Dynamics
Creators: name: Zha, Junrong
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Other earth sciences not elsewhere classified

description: The land ecosystems in northern high latitudes (>45° N) occupy 22% of the global surface and store more than 1600 Pg soil organic carbon. Warming in this region has been documented during the past decades. Warming-induced changes in regional carbon dynamics are expected to loom large in the global carbon cycle and exert large feedbacks to the global climate system. Numerous Earth System Models have been widely used to quantify the response of terrestrial ecosystem carbon dynamics to climatic changes. However, predictions of terrestrial ecosystem carbon responses to increasing levels of atmospheric carbon dioxide (CO2) and climate change is still uncertain due to model limitations. The limitations include relatively low levels of representation of ecosystem processes that determine the exchanges of water, energy, and carbon between land ecosystems and the atmosphere and omitting some key biogeochemical mechanisms. To improve model realism and provide a better projection of the Arctic carbon dynamics, this dissertation developed three new versions of a process-based biogeochemistry models that involve more fundamental processes of terrestrial ecosystems. First, microbial dynamics and enzyme kinetics that catalyze soil carbon decomposition have been incorporated into the extant terrestrial ecosystem model TEM to remedy the inadequate representation of soil decomposition process. Furthermore, a vital microbial life-history trait, microbial dormancy, has been implemented into previous microbial-based model to consider the impacts of microbial dormancy in modeling. Additionally, the role of moss in the Arctic terrestrial ecosystem carbon quantification was also demonstrated by incorporating moss and higher plant interactions in modelling.
Flood Rescue: A Gender-Inclusive Integrated STEM Curriculum Unit
Creators: name: Emily A. Dare, Dave Rafferty
Publisher: name: The Institute for the Promotion of Teaching Science and Technology (IPST), Ministry of Education
Year: 2017
Subjects: STEM Education, Engineering Design, Physics, Gender Equity

description: K-12 STEM Education, 3, 2 (April-June)
Developing 21st Century Skills through a Constructivist-Constructionist Learning Environment
Creators: name: Lay Ah-Nam, Kamisah Osman
Publisher: name: The Institute for the Promotion of Teaching Science and Technology (IPST), Ministry of Education
Year: 2017
Subjects: 21st century skills, constructionism, constructivism, IDPCR model, learning through designing

description: K-12 STEM Education, 3, 2 (April-June)
Peritoneal protein clearance, fluid overload, and cardiovascular events in patients undergoing peritoneal dialysis: a prospective cohort study
Creators: name: Ye, Hongjian
name: Liu, Ruihua
name: Cao, Peiyi
name: Guo, Qunying
name: Chen, Wei
name: Mao, Haiping
name: Yang, Xiao
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Science Policy
subject: Virology

description: The relationship among higher peritoneal protein clearance (PPCl), fluid overload, and increased risk of cardiovascular (CV) events has not been well clarified in peritoneal dialysis (PD) patients. We aimed to examine their associations in a prospective cohort study. Eligible patients were enrolled from a single center, and PPCl was calculated based on the daily dialysate protein loss corrected for serum albumin. Fluid overload was defined as extracellular water (ECW)/total body water (TBW) ≥0.400 measured by bioelectrical impedance analysis (BIA). The primary outcome was CV events. In total, 351 patients were included in this study. After adjustment for confounders, every 5 mL/day increase in PPCl was independently associated with a 27% higher risk of fluid overload determined by BIA (odds ratio: 1.27, 95% confidence interval (CI): 1.17–1.37). After a median follow-up of 46.8 months, 90 patients (25.6%) experienced CV events. In competing risk models adjusted for confounders, both fluid overload and every 5 mL/day increase in PPCl were independently associated with 70% (subdistribution hazard ratio (SHR):1.70, 95%CI: 1.06–2.74) and 9% (SHR: 1.09, 95%CI: 1.04–1.14) increased risk of CV events, respectively. When fluid overload and PPCl were added simultaneously to the models, PPCl remained a strong independent predictor (SHR: 1.07; 95%CI: 1.03–1.13). Higher PPCl was independently associated with fluid overload determined by BIA in PD patients. Moreover, higher PPCl was independently associated with an increased risk of CV events.
sj-docx-2-hol-10.1177_09596836211033197 – Supplemental material for Organic geochemical characterization of Early-Mid-Holocene swamp deposits near the Neolithic settlement in Yenikapı-Istanbul: Assessment of environmental variability and anthropogenic impacts
Creators: name: Yalçın, Mehmet Namık
name: Wilkes, Heinz
name: Plessen, Birgit
Publisher: name: SAGE Journals
Year: 2021
Subjects: Geography
History

description: Supplemental material, sj-docx-2-hol-10.1177_09596836211033197 for Organic geochemical characterization of Early-Mid-Holocene swamp deposits near the Neolithic settlement in Yenikapı-Istanbul: Assessment of environmental variability and anthropogenic impacts by Mehmet Namık Yalçın, Heinz Wilkes and Birgit Plessen in The Holocene
IGFBP2 and IGFBP4 interact to activate complement pathway in diabetic kidney disease
Creators: name: Liang, Jieling
name: Huang, Yangxiao
name: Peng, Daping
name: Xie, Yali
name: Liu, Yifei
name: Lu, Xiuxia
name: Xu, Junfa
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease globally. Recent research has identified insulin-like growth factor-binding proteins 2 (IGFBP2) and 4 (IGFBP4) as potential biomarkers for DKD. Overactivation of the complement pathway in DKD remains poorly understood. Blood samples were collected from patients for proteomic analysis, complemented by both in vitro and in vivo experiments to investigate the roles of IGFBP2, IGFBP4, and the complement pathway in DKD. Elevated levels of IGFBP2 and IGFBP4 were observed in DKD patients. The levels of IGFBP2 and IGFBP4 increased in DKD mice, accompanied by the activation of the complement pathway, and a deterioration in renal function. High glucose and serum from DKD mice stimulated an increase in the levels of IGFBP2 and IGFBP4 in HK-2 cells. The supernatant from HK-2 cells was used to culture THP-1 cells, resulted in an increase in the M1 type of THP-1 cells, a decrease in the M2 type, and activation of the complement pathway. The supernatant from THP-1 cells affected the growth of primary human renal podocytes. The exogenous addition of IGFBP2 and IGFBP4 proteins to primary human renal podocytes did not affect their growth. However, when human renal podocytes were cultured with the supernatant from THP-1 cells, the growth of the podocytes was affected. IGFBP2 and IGFBP4 interact to stimulate the activation of the complement pathway in macrophages, which induces podocyte apoptosis and subsequently promotes the development of DKD.