cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Experimental Investigation of Waste Clay Bricks as an Alternative to Cement in Pavement Construction
Creators: name: Migunthanna Kariyakaranage, Janitha
Publisher: name: Swinburne
Year: 2024

description: The primary sustainability challenge in the concrete pavement industry is the high energy consumption and greenhouse gas emissions associated with ordinary Portland cement (OPC) manufacturing. This research focused on developing low-carbon binder material to fully replace OPC in concrete using waste clay bricks. Waste clay bricks sourced from construction and demolition waste was processed and combined with other industrial wastes such ash fly ash and slag, and alkaline activators to produce alternative cements. This research was able to develop pavement concrete with similar or better mechanical, durability and serviceability performance and superior environmental performance compared to conventional concrete with OPC.
title: La Trombosis Venosa Cerebral, un reto diagnóstico.
Creators: name: Salame Gamarra, Fares
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Head and neck
subject: Vascular

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
La trombosis venosa cerebral (TVC) es una patología grave,
infradiagnosticada,
y a menudo,
insospechada por el clínico.
El papel del radiólogo es importante,
pues sólo realizando un estudio de imagen dirigido,se podrá realizar el diagnóstico....
title: Evaluación radiologica de la patologia urgente no traumatica raquimedular
Creators: name: Vargas Orozco, Ivan Mauricio
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Acute
subject: Neoplasia
subject: Infection
subject: Education
subject: CT
subject: CT-High Resolution
subject: MR
subject: Emergency
subject: Anatomy

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
•Describir las causas más comunes de patología aguda raquimedular no traumatica que se pueden presentar en la urgencia.•Revisar sus manifestaciones clínicas,
e ilustrar el espectro de hallazgos radiologicos mediante: la Resonancia Magnetica...
title: Eco-doppler con potenciador (EDP) frente a angio-TC en el seguimiento de pacientes con aneurisma de aorta abdominal (AAA) tratados con EVAR: nuestra experiencia
Creators: name: Sanchis Garcia, Juan Manuel
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Prostheses
subject: Aneurysms
subject: Comparative studies
subject: Outcomes analysis
subject: Stents
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: CT-Angiography
subject: Abdomen
subject: Vascular
subject: Interventional vascular

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
1. Introducción.
Objetivos El tratamiento endovascular (EVAR) de los aneurismas de aorta abdominal (AAA) es una alternativa a la cirugía abierta aceptada en pacientes seleccionados (1). Tras realizar un tratamiento endovascular (EVAR) de un...
title: El informe radiológico de la mama orientado al clínico.
Creators: name: Vilaplana López, Alejandra
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Structured reporting
subject: Education
subject: Ultrasound
subject: Mammography
subject: Breast

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Durante varios años venimos comprobando que el seguimiento de las pacientes que se realizan mamografia o ecografia mamaria no es siempre el que nosotros consideramos másadecuado.
Se controlan imagenestípicamente benignas,
se hacen seguimientos...
Berichterstattung unter der Klimarahmenkonvention der Vereinten Nationen und dem Kyoto-Protokoll 2020
Creators: name: (:Unkn) Unknown
Publisher: name: Umweltbundesamt
Year: 2020
Subjects: subject: Klimarahmenkonvention
subject: Treibhausgasinventar
subject: Treibhausgasemission
subject: UNFCCC
subject: Entwicklung der Treibhausgasemissionen
subject: Treibhausgasausstoß
subject: Klima | Energie

description: Als Vertragsstaat der Klimarahmenkonvention der Vereinten Nationen (UNFCCC) ist Deutschland seit 1994 dazu verpflichtet, Inventare zu nationalen Treibhausgasemissionen zu erstellen, zu veröffentlichen und regelmäßig fortzuschreiben. Gemäß Entscheidung 24/CP.19 müssen alle im ANNEX I der Klimarahmenkonvention aufgeführten Staaten jährlich einen Nationalen Inventarbericht (NIR) erstellen und übermitteln, der detaillierte und vollständige Angaben über den gesamten Prozess der Erstellung der Treibhausgasinventare bereitstellt. Durch diesen Bericht soll die Transparenz, Konsistenz und Vergleichbarkeit der Inventare sichergestellt und der unabhängige Überprüfungsprozess unterstützt werden. Quelle: http://www.umweltbundesamt.de
description: Als Vertragsstaat der Klimarahmenkonvention der Vereinten Nationen (⁠UNFCCC⁠) ist Deutschland seit 1994 dazu verpflichtet, Inventare zu nationalen Treibhausgasemissionen zu erstellen, zu veröffentlichen und regelmäßig fortzuschreiben. Gemäß Entscheidung 24/CP.19 müssen alle im ANNEX I der Klimarahmenkonvention aufgeführten Staaten jährlich einen Nationalen Inventarbericht (NIR) erstellen und übermitteln, der detaillierte und vollständige Angaben über den gesamten Prozess der Erstellung der Treibhausgasinventare bereitstellt. Durch diesen Bericht soll die Transparenz, Konsistenz und Vergleichbarkeit der Inventare sichergestellt und der unabhängige Überprüfungsprozess unterstützt werden.
Characterization of the insecticidal crystal protein from Bacillus thuringiensis.
Creators: name: Bietlot, Henri P.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Chemistry, Biochemistry.

description: Bacillus thuringiensis produces a crystalline inclusion body composed of a 130-kDa protein which is rendered toxic upon ingestion by lepidoteran larvae. It was shown that proteinases adsorb on the surface of the crystalline body lead to proteolysis of the protein crystal especially on solubilization in alkali. Extensive washing of the protein crystal was shown to remove these proteinases and give a stable preparation. Exposure of the protein crystal to simulated sunlight results in a loss of toxicity and in the destruction of the side-chains of tryptophan, histidine, tyrosine and methionine. Destruction of amino acid side-chains is not the primary cause of the photo-inactivation of the protein crystal. The finding that all the disulfide linkages in the protein crystal are interchain and symmetrical accounts for its alkaline lability and for the high degree of conservation in the primary structure of the cystine-containing regions of the protein from various subspecies. (Abstract shortened by UMI.)
Wellbeing in Coeliac Disease: A Psychosocial Investigation into the Relationship Between Gastrointestinal Symptoms and Quality of Life
Creators: name: Möller, Stephan Paul
Publisher: name: Swinburne
Year: 2024

description: Coeliac disease is a common chronic inflammatory gastrointestinal condition requiring vigilant and lifelong avoidance of dietary gluten. Gastrointestinal and quality of life issues often persist, yet little research has examined how psychosocial factors relate to or play a role in these challenges. This research extended knowledge in this area by isolating bidirectional relationships between gastrointestinal symptoms, psychosocial factors, and quality of life over time. The novel longitudinal methods employed in this research further developed our understanding of the COVID-19 pandemic's impact on this population and provided pivotal support for several processes of the common-sense model of illness.
Effect of Short-Term Supplementation with Ready-to-Use Therapeutic Food or Micronutrients for Children after Illness for Prevention of Malnutrition: A Randomised Controlled Trial in Uganda
Creators: name: Van Der Kam, Saskia
name: Roll, Stephanie
name: Swarthout, Todd
name: Edyegu-Otelu, Grace
name: Matsumoto, Akiko
name: Xavier Kasujja, Francis
name: Casademont, Cristian
name: Shanks, Leslie
name: Salse-Ubach, Nuria
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Globally, Médecins Sans Frontières (MSF) treats more than 300,000 severely malnourished children annually. Malnutrition is not only caused by lack of food but also by illnesses and by poor infant and child feeding practices. Breaking the vicious cycle of illness and malnutrition by providing ill children with nutritional supplementation is a potentially powerful strategy for preventing malnutrition that has not been adequately investigated. Therefore, MSF investigated whether incidence of malnutrition among ill children <5 y old could be reduced by providing a fortified food product or micronutrients during their 2-wk convalescence period. Two trials, one in Nigeria and one in Uganda, were conducted; here, we report on the trial that took place in Kaabong, a poor agropastoral region of Karamoja, in east Uganda. While the region of Karamoja shows an acute malnutrition rate between 8.4% and 11.5% of which 2% to 3% severe malnutrition, more than half (58%) of the population in the district of Kaabong is considered food insecure. Methods and Findings We investigated the effect of two types of nutritional supplementation on the incidence of malnutrition in ill children presenting at outpatient clinics during March 2011 to April 2012 in Kaabong, Karamoja region, Uganda, a resource-poor region where malnutrition is a chronic problem for its seminomadic population. A three-armed, partially-blinded, randomised controlled trial was conducted in children diagnosed with malaria, diarrhoea, or lower respiratory tract infection. Non-malnourished children aged 6 to 59 mo were randomised to one of three arms: one sachet/d of ready-to-use therapeutic food (RUTF), two sachets/d of micronutrient powder (MNP), or no supplement (control) for 14 d for each illness over 6 mo. The primary outcome was the incidence of first negative nutritional outcome (NNO) during the 6 mo follow-up. NNO was a study-specific measure used to indicate progression to moderate or severe acute malnutrition; it was defined as weight-for-height z-score
Association of Common Polymorphisms in the Nicotinic Acetylcholine Receptor Alpha4 Subunit Gene with an Electrophysiological Endophenotype in a Large Population-Based Sample
Creators: name: Mobascher, A.
name: Diaz-Lacava, A.
name: Wagner, M.
name: Gallinat, J.
name: Wienker, T. F.
name: Drichel, D.
name: Becker, T.
name: Steffens, M.
name: Dahmen, N.
name: Gründer, G.
name: Thürauf, N.
name: Kiefer, F.
name: Kornhuber, J.
name: Toliat, M. R.
name: Thiele, H.
name: Nürnberg, P.
name: Steinlein, O.
name: Winterer, G.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Variation in genes coding for nicotinic acetylcholine receptor (nAChR) subunits affect cognitive processes and may contribute to the genetic architecture of neuropsychiatric disorders. Single nucleotide polymorphisms (SNPs) in the CHRNA4 gene that codes for the alpha4 subunit of alpha4/beta2-containing receptors have previously been implicated in aspects of (mostly visual) attention and smoking-related behavioral measures. Here we investigated the effects of six synonymous but functional CHRNA4 exon 5 SNPs on the N100 event-related potential (ERP), an electrophysiological endophenotype elicited by a standard auditory oddball. A total of N = 1,705 subjects randomly selected from the general population were studied with electroencephalography (EEG) as part of the German Multicenter Study on nicotine addiction. Two of the six variants, rs1044396 and neighboring rs1044397, were significantly associated with N100 amplitude. This effect was pronounced in females where we also observed an effect on reaction time. Sequencing of the complete exon 5 region in the population sample excluded the existence of additional/functional variants that may be responsible for the observed effects. This is the first large-scale population-based study investigation the effects of CHRNA4 SNPs on brain activity measures related to stimulus processing and attention. Our results provide further evidence that common synonymous CHRNA4 exon 5 SNPs affect cognitive processes and suggest that they also play a role in the auditory system. As N100 amplitude reduction is considered a schizophrenia-related endophenotype the SNPs studied here may also be associated with schizophrenia outcome measures.
Describing perspectives of health care professionals on active surveillance for the management of prostate cancer
Creators: name: Pang, Kittie
name: Fitch, Margaret
name: Ouellet, Veronique
name: Chevalier, Simone
name: Drachenberg, Darrel E
name: Finelli, Antonio
name: Lattouf, Jean-Baptiste
name: So, Alan
name: Sutcliffe, Simon
name: Tanguay, Simon
name: Saad, Fred
name: Mes-Masson, Anne-Marie
Publisher: name: BioMed Central
Year: 2018

description: Background: Over the last decade, active surveillance has proven to be a safe approach for patients with low-risk prostate cancer. Although active surveillance presents several advantages for both patients and the health care system, all eligible patients do not adopt this approach. Our goal was to evaluate the factors that influence physicians to recommend active surveillance and the barriers that impact adherence to this approach. Methods: Focus groups (n = 5) were held with physicians who provided care for men with low-risk prostate cancer and had engaged in conversations with men and their families about active surveillance. The experience of health care professionals (HCPs) was captured to understand their decisions in proposing active surveillance and to reveal the barriers and facilitators that affect the adherence to this approach. A content analysis was performed on the verbatim transcripts from the sessions. Results: Although physicians agreed that active surveillance is a suitable approach for low-risk prostate cancer patients, they were concerned about the rapidly evolving and non-standardized guidelines for patient follow-up. They pointed out the need for additional tools to appropriately identify proper patients for whom active surveillance is the best option. Urologists and radiation-oncologists were keen to collaborate with each other, but the role of general practitioner remained controversial once patients were referred to a specialist. Conclusions: Integration of more reliable tools and/or markers in addition to more specific guidelines for patient follow-up would increase the confidence of both patients and physicians in the choice of active surveillance.
New applications, new global audiences: educators repurposing and reusing 3D virtual and immersive learning resources
Creators: name: Gregory, Sue
name: Gregory, Brent
name: Wood, Denise
name: O'Connell, Judy
name: Grant, Scott
name: Hillier, Mathew
name: Butler, Des
name: Masters, Yvonne
name: Stokes-Thomson, Frederick
name: McDonald, Marcus
name: Nikolic, Sasha
name: Ellis, David
name: Kerr, Tom
name: de Freitas, Sarah
name: Farley, Helen
name: Schutt, Stefan
name: Sim, Jenny
name: Gaukrodger, Belma
name: Jacka, Lisa
name: Doyle, Jo
name: Blyth, Phil
name: Corder, Deborah
name: Reiners, Torsten
name: Linegar, Dale
name: Hearns, Merle
name: Cox, Robert
name: Jegathesan, Jay Jay
name: Sukunesan, Suku
name: Flintoff, Kim
name: Irving, Leah
Publisher: name: Swinburne
Year: 2024

description: There continues to be strong interest among established, experienced academic users of 3D virtual environments for their sustained educational use. Consistent with global trends, they plan to further develop and optimise existing applications, reuse skills and experiences gained to develop new applications, and to share and reuse existing virtual resources. This is against a background of varied support from institutions, colleagues, students, funding bodies and also changing understanding and awareness of virtual environments and virtual reality by the general community as a result of consumer developments such as the popularity of multi - user online role playing amongst both children and adults, and the acquisition of technologies by companies with deeply entrenched technologies. At the same time, the ongoing development and availability of new multiuser virtual environment platforms, associated peripherals and virtual reality technologies promise new and exciting opportunities for educators to collaborate w ith researchers on a global scale, while also exploring the affordances of these technologies for enhancing the learning outcomes for an increasingly diverse and distributed student population.
In vacuo cross-linking of proteins: A novel approach with theoretical and practical applications to the study of proteins
Creators: name: Simons, Brigitte L
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Chemistry, Biochemistry.

description: This thesis describes the hypothesis and subsequent demonstration that proteins can be covalently cross-linked without use of chemical reagents by simply incubating the protein or proteins in the lyophilized state under appropriate conditions in a vacuum. This in vacuo cross-linking requires the interaction of a protonated positively-charged amino group on one molecule with a deprotonated negatively-charged carboxylate group on a second. A zerolength cross-link is formed by a condensation reaction between the two groups with the release of water. A reaction mechanism is proposed in which amide bond formation occurs by means of a proton transfer from the protonated amino group to an interacting carboxylate group followed by a nucleophilic attack by the deprotonated amino group on the carboxylic acid group (protonated). The reaction is driven by the removal of the released water by the vacuum. It was observed that proteins appeared to form trace amounts of covalently bonded products, visualized on denaturing and reducing gel electrophoresis and probed with sensitive detection methods, if the protein preparations had been subjected to a vacuum. This observation prompted the hypothesis: can proteins be covalently cross-linked by incubating lyophilized protein under vacuum? This hypothesis was tested using Ribonuclease A (RNase A) as a model protein and the in vacuo heating of RNase A demonstrated that covalently cross-linked products arise with dimer being the major product. Structural characterization of the in vacuo RNase A dimer demonstrated that the dimer was composed of a single amide cross-link at positions lysine 66 and glutamic acid 9. This dimenc protein is proposed to adopt a new conformation not previously reported as a known RNase A X-ray crystallographic structure. The in vacuo RNase A dimer also demonstrated a 2-fold increase in enzymatic activity compared to monomeric RNase A towards both double stranded and single stranded RNA, both in the presence and absence of the cytosolic ribonuclease inhibitor. The in vacuo cross-linking of protein was shown to be a general phenomenon as all proteins tested produced covalently cross-linked oligomers. The utility of this cross-linking method was then expanded to the cross-linking of proteins to functionalized solid supports and the covalent cross-linking of enzymes to antibodies to produce highly sensitive immunoconjugates for Western Blot analysis and ELISAs. A discussion of the in vacuo cross-linking of a de novo designed protein, milk bundle, and its dimeric 4-helix bundle structural characterization is also presented.
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
Creators: name: Couch, Fergus J.
name: Varon-Mateeva, Raymonda
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: Biological sciences
subject: FOS: Biological sciences
subject: Cancer
subject: Genetics
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P<5 × 10−8) with oestrogen receptor (ER)-negative breast cancer and BRCA1-associated breast cancer risk. In this study, to identify new ER-negative susceptibility loci, we performed a meta-analysis of 11 genome-wide association studies (GWAS) consisting of 4,939 ER-negative cases and 14,352 controls, combined with 7,333 ER-negative cases and 42,468 controls and 15,252 BRCA1 mutation carriers genotyped on the iCOGS array. We identify four previously unidentified loci including two loci at 13q22 near KLF5, a 2p23.2 locus near WDR43 and a 2q33 locus near PPIL3 that display genome-wide significant associations with ER-negative breast cancer. In addition, 19 known breast cancer risk loci have genome-wide significant associations and 40 had moderate associations (P<0.05) with ER-negative disease. Using functional and eQTL studies we implicate TRMT61B and WDR43 at 2p23.2 and PPIL3 at 2q33 in ER-negative breast cancer aetiology. All ER- negative loci combined account for ~11% of familial relative risk for ER- negative disease and may contribute to improved ER-negative and BRCA1 breast cancer risk prediction.
Smart Predictive Maintenance for pro-active machine process using Machine Learning
Creators: name: Rajendiran, Vinod
Publisher: name: Swinburne
Year: 2024

description: The research on hybrid models for predictive maintenance paves the way for more advanced and intelligent maintenance strategies. It empowers industries to move from reactive maintenance practices to proactive and data-driven approaches. The integration of machine learning and hybrid models enables better resource utilization, improved equipment reliability, and increased productivity. As a result, companies can achieve higher levels of operational efficiency, reduce maintenance costs, and enhance customer satisfaction through uninterrupted production processes.
Beschreibung der maßnahmenbasierten und hypothetischen Maßnahmenbündel im Projekt PAREST
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2013
Subjects: subject: Feinstaub
subject: Luftverunreinigende Partikel
subject: Luftreinhalteplanung
subject: Luft
subject: Air

description: In diesem Bericht werden die im Rahmen von PAREST modellierten „realen“ Maßnahmenbündel beschrieben. Darüber hinaus werden auch die hypothetischen Maßnahmenbündel "Reduzierter Konsum von tierischem Eiweiß", "Der Ersatz von Holzfeuerungen durch Ölfeuerungen" sowie "Die Kombination von Klimaschutzszenarien mit realen Maßnahmenbündeln" beschrieben.
title: Redistributing ill-defined causes of death - a case study from the BURDEN 2020-project in Germany
title: Redistributing ill-defined causes of death
titleType: AlternativeTitle
Creators: name: Gruhl, Heike
name: Wengler, Annelene
name: Plaß, Dietrich
Publisher: name: My University
Year: 2021
Subjects: Todesursache
Sterblichkeit

description: Background The cause of death statistics in Germany include a relatively high share (26% in 2017) of ill-defined deaths (IDD). To make use of the cause of death statistics for Burden of Disease calculations we redistribute those IDD to valid causes of death. Methods The process of proportional redistribution is described in detail. It makes use of the distribution of the valid ICD-codes in the cause of death data. We use examples of stroke, diabetes, and heart failure to illustrate how IDD are reallocated. Results The largest increases in the number of deaths for both women and men were found for lower respiratory infections, diabetes mellitus, and stroke. The numbers of deaths for these causes more than doubled after redistribution. Conclusion This is the first comprehensive redistribution of IDD using the German cause of death statistics. Performing a redistribution is necessary for burden of disease analyses, otherwise there would be an underreporting of certain causes of death or large numbers of deaths coded to residual or unspecific codes. © The Author(s). 2021
title: Neue Allianzen für sozial-ökologische Transformationen
title: Neue Allianzen für sozial-ökologische Transformationen
titleType: AlternativeTitle
Creators: name: Sharp, Helen
name: Petschow, Ulrich
name: Arlt, Hans-Jürgen
Publisher: name: Umweltbundesamt
Year: 2020
Subjects: subject: Sozialer Wandel
subject: Ökologie
subject: Zivilgesellschaft
subject: Zusammenarbeit
subject: Gesellschaftliche Transformation
subject: sozial
subject: ökologisch
subject: Kooperation
subject: Nachhaltigkeit | Strategien | Internationales

description: Eine nachhaltige Entwicklung impliziert weitreichende Transformationen zentraler gesellschaftlicher Systeme und erfordert neue integrierte sozial-ökologische Gestaltungsansätze, sowohl seitens staatlicher Akteure als auch seitens der Zivilgesellschaft. Die Broschüre fasst die Erkenntnisse einer umfassenden Untersuchung zivilgesellschaftlicher Kooperationen von umweltpolitischen Akteuren mit Gewerkschaften, Sozial- und Wohlfahrtsverbänden zusammen. Sie entwirft Handlungsempfehlungen, um eine Verständigung und weitere Aktivitäten zwischen den zivilgesellschaftlichen Verbänden und mit staatlicher Politik zu unterstützen und setzt Impulse, vorhandene Potentiale zu heben und Hemmnisse zu überwinden. Quelle: https://www.umweltbundesamt.de
description: Eine nachhaltige Entwicklung impliziert weitreichende Transformationen zentraler gesellschaftlicher Systeme und erfordert neue integrierte sozial-ökologische Gestaltungsansätze, sowohl seitens staatlicher Akteure als auch seitens der Zivilgesellschaft. Die Broschüre fasst die Erkenntnisse einer umfassenden Untersuchung zivilgesellschaftlicher Kooperationen von umweltpolitischen Akteuren mit Gewerkschaften, Sozial- und Wohlfahrtsverbänden zusammen. Sie entwirft Handlungsempfehlungen, um eine Verständigung und weitere Aktivitäten zwischen den zivilgesellschaftlichen Verbänden und mit staatlicher Politik zu unterstützen und setzt Impulse, vorhandene Potentiale zu heben und Hemmnisse zu überwinden.
Wave mixing in extreme ultraviolet region for study of atomic and molecular dynamics
Creators: name: Chau, Huy Thong
Publisher: name: Swinburne
Year: 2024

description: We use a single chamber with Argon and Nitrogen gas to combine different light pulses and generate new light waves in the extreme ultraviolet region. We found that the properties of the gas affect how the new waves evolve over time. We examine multiple interaction regime of atomic and molecular gas with multiple colours of light and discuss the understanding of matter at the atomic and molecular level. This study could help us better understand process such as chemical reactions and energy transfer, leading to new developments in materials science, chemistry, pharmaceuticals, and laser technology.
Maßnahmen zur Verminderung des Eintrages von Mikroschadstoffen in die Gewässer
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: subject: Emissionsminderung
subject: Kosten
subject: Stoffstromanalyse
subject: Mikroschadstoffe
subject: Spurenstoff
subject: 4. Reinigungsstufe
subject: Abwasserbehandlungsanlage
subject: Wasser
subject: Water

description: Für viele Mikroschadstoffe, wie z. B. Inhaltsstoffe von Haushaltchemikalien, Einsatzstoffe in Gewerbe und Industrie (insbesondere bei kleinen und mittleren Betrieben), Arzneistoffe und Biozide stellt der Eintrag über das kommunale Abwassersystem den dominierenden Eintragspfad in die Gewässer dar. Vor diesem Hintergrund war das übergreifende Projektziel, geeignete Maßnahmen bzw. Kombinationen von Maßnahmen und deren Randbedingungen zur Verminderung des Eintrages von Mikroschadstoffen über das kommunale Abwassersystem in die Gewässer zu erarbeiten, die sich durch eine hohe Kosteneffizienz auszeichnen. Für zwölf ausgewählte Stoffe wurden die emissionsrelevanten Stoffflüsse analysiert und teilweise zusätzlich der Stoffeintrag modelliert. Die Ergebnisse dienten als Grundlage für die Ableitung von Emissionsminderungsmaßnahmen. Dabei wurden auch Untersuchungen zu Kosten und zur Wirksamkeit der Einführung einer vierten Reinigungsstufe in kommunalen Kläranlagen und der dabei zu berücksichtigen Rahmenbedingungen vorgenommen. Gleichzeitig zeigen die Arbeiten, dass auch quellenorientierte sowie dezentrale Maßnahmen je nach betrachteten Stoffe eine kosteneffiziente Möglichkeit darstellen und einen wesentlichen Beitrag zur Umsetzung des Verursacherprinzips leisten können.
Quelle: http://www.umweltbundesamt.de/
description: Für viele Mikroschadstoffe, wie z. B. Inhaltsstoffe von Haushaltchemikalien, Einsatzstoffe in Gewerbe und Industrie (insbesondere bei kleinen und mittleren Betrieben), Arzneistoffe und Biozide stellt der Eintrag über das kommunale Abwassersystem den dominierenden Eintragspfad in die Gewässer dar. Vor diesem Hintergrund war das übergreifende Projektziel, geeignete Maßnahmen bzw. Kombinationen von Maßnahmen und deren Randbedingungen zur Verminderung des Eintrages von Mikroschadstoffen über das kommunale Abwassersystem in die Gewässer zu erarbeiten, die sich durch eine hohe Kosteneffizienz auszeichnen. Für zwölf ausgewählte Stoffe wurden die emissionsrelevanten Stoffflüsse analysiert und teilweise zusätzlich der Stoffeintrag modelliert. Die Ergebnisse dienten als Grundlage für die Ableitung von Emissionsminderungsmaßnahmen.  Dabei wurden auch Untersuchungen zu Kosten und zur Wirksamkeit der Einführung einer vierten Reinigungsstufe in kommunalen Kläranlagen und der dabei zu berücksichtigen Rahmenbedingungen vorgenommen. Gleichzeitig zeigen die Arbeiten, dass auch quellenorientierte sowie dezentrale Maßnahmen je nach betrachteten Stoffe eine kosteneffiziente Möglichkeit darstellen und einen wesentlichen Beitrag zur Umsetzung des Verursacherprinzips leisten können.
Genome dynamics in barley (Hordeum vulgare L) cultivars: Molecular diversity, evolution, and DNA fingerprinting
Creators: name: Soleimani, Vahab D
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Biology, Botany.
subject: Biology, Genetics.
subject: Agriculture, Plant Culture.

description: In the absence of whole genome sequencing, molecular markers are indispensable tools for the study of genome evolution, genetic diversity measurements, and genotype identification. We have used sequence-specific amplified polymorphism (S-SAP) markers that were derived from the BARE-1, an active retrotransposon of barley, to measure the contribution of this element to the evolution of barley genome among 103 cultivars that are commonly grown in Canada and the United States. The results were compared to the genome diversity measures obtained by the single nucleotide polymorphisms (SNP). The barley populations were divided into groups based on various agronomic traits such as end use, i.e., feed versus malting, and seed morphology, i.e., naked versus covered kernel. Analysis of the genetic structure in the population using analysis of molecular variance (AMOVA) for both S-SAP and SNP attributed the largest co-variance component (90%) to the genetic diversity among cultivars within groups. Co-variance component between groups was about 6% which indicated that there was no justification for population differentiation along the set based upon agronomic traits. Genetic relationships among cultivars was assessed by cluster analysis with UPGMA and found to vary substantially between S-SAP and SNP datasets. Quantitative analysis of BARE-1 retrotransposon with real-time PCR in a small group of cultivars showed significant differences in the copy number of the element among cultivars. Most of the BARE-1 elements were in the form of solo LTRs, indicating a high rate of homologous recombination between retrotransposon copies in the genome. Differences of up to 3000 BARE-1 copies per haploid genome were found among cultivars that have been developed and registered within the past three decades. Informative SNPs such as those with high polymorphic information content (PIC) values were used to generate identification keys to distinguish barley cultivars which were otherwise indistinguishable at the morphological and biochemical levels.
Real-time Electromyogram-based Gesture Recognition using Machine Learning for Controlling Powered Wheelchair
Creators: name: Iqbal, Hassam
Publisher: name: Swinburne
Year: 2024

description: This thesis enhances powered wheelchair control for motor-impaired individuals using sEMG signals and AI-based gesture recognition. Five gestures control unidirectional steering, achieving 95.50% accuracy in real-time navigation. For finger impairments, user-independent classification methods like MC-SVM and DT ensure high recognition accuracy. The study also introduces a human-machine interface utilizing an artificial neural network, achieving 99.06% accuracy and enabling collision-free navigation. This technology has the potential to empower individuals with disabilities, offering improved mobility and independence.
How Do Conservation and the Tourism Industry Affect Local Livelihoods? A Comparative Study of Two Nature Reserves in China
Creators: name: Wang, Weiye
name: Liu, Jinlong
name: Kozak, Robert A.
name: Jin, Mengmeng
name: Innes, John L.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Drawing on a comparison of two different nature reserves (NRs) in China, this paper explores the effect of the establishment of the NRs and the associated tourism industry development on local livelihoods, and analyzes why they differed. One hundred semi-structured interviews were administered with local elites, villagers, and government officials to identify livelihood changes. Based on a modified sustainable livelihoods framework, we found that the livelihoods of people living in both NRs had improved, but there was a loss of traditional culture and weakened social connections. The provision of alternative livelihoods options was critical for local people, with these options needing to have strong connections to China’s development policies. The results point to the importance of providing alternative livelihood strategies when establishing new conservation areas. This requires holistic management plans that not only address conservation, but also consider the impacts on local people.
cSPider – Evaluation of a Free and Open-Source Automated Tool to Analyze Corticomotor Silent Period
Creators: name: Wilke, Skadi
name: Groenveld, Dennis
name: Grittner, Ulrike
name: List, Jonathan
name: Floeel, Agnes
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background The corticomotor silent period (CSP), as assessed noninvasively by transcranial magnetic stimulation (TMS) in the primary motor cortex, has been found to reflect intracortical inhibitory mechanisms. Analysis of CSP is mostly conducted manually. However, this approach is time-consuming, and comparison of results from different laboratories may be compromised by inter- rater variability in analysis. No open source program for automated analysis is currently available. Methods/Results Here, we describe cross-validation with the manual analysis of an in-house written automated tool to assess CSP (cSPider). Results from automated routine were compared with results of the manual evaluation. We found high inter-method reliability between automated and manual analysis (p<0.001), and significantly reduced time for CSP analysis (median = 10.3 sec for automated analysis of 10 CSPs vs. median = 270 sec for manual analysis of 10 CSPs). cSPider can be downloaded free of charge. Conclusion cSPider allows automated analysis of CSP in a reliable and time- efficient manner. Use of this open-source tool may help to improve comparison of data from different laboratories.
Needs, service-costs and outcomes in foster care in three Ontario children's aid societies
Creators: name: MacDonald, Joan Matilda
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Social Work.
subject: Psychology, Clinical.
subject: Sociology, Public and Social Welfare.

description: Costing studies are necessary to ensure that scarce funds are allocated to services that best meet children's needs and lead to positive changes in their functioning. The Production of Welfare (POW) model for costing social services provides a conceptual framework for examining variations in cost in relation to needs and outcomes. The few studies that have looked at costs of services to children and youth suggest that health needs, emotional/behavioural problems, gender and age may influence cost. Our study questions were: (1) What are the average annual per-child costs of foster care? (2) Do higher health needs predict higher costs? (3) Do higher costs during a 12-month period predict better outcomes? The outcomes included in the study were self-esteem, prosocial behaviour, emotional distress/anxiety, conduct disorder/physical aggression, indirect aggression and ill-health. The total average annual opportunity cost per child was $22,892 (N=119). Greater ill-health at baseline predicted higher costs. Cost did not predict changes on self-esteem, prosocial behaviour and emotional distress/anxiety. Contrary to expectations, higher costs were associated with increases in conduct disorder/physical aggression, indirect aggression and ill-health over the 12 months of the study. Kinship care was less expensive than regular foster care, but the study included only 8 children in kinship care. Our results suggest that higher expenditures are targeted at children with greater health needs. Costs may not have yet been able to predict positive changes in outcomes because the time period of the study was for the interventions to have the impact on behaviour that would bring about positive changes. This means that further research with a longer follow-up period is required. A prospective cost study could provide a more complete description of the total costs required to support a child in foster care. Given the small number of participants in kinship care in our study, the relationship between kinship care and cost can only be viewed as exploratory. A larger sample of children in kinship care could provide more information on the costs of kinship care and the relationship between costs and outcomes in kinship care in comparison to regular foster care.
Unterirdische Raumplanung - Vorschläge des Umweltschutzes zur Verbesserung der über- und untertägigen Informationsgrundlagen, zur Ausgestaltung des Planungsinstrumentariums und zur nachhaltigen Lösung von Nutzungskonflikten
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: Unterirdische Raumplanung
Raumordnung
Energiespeicher
Fachplanung

description: Das Forschungsprojekt befasst sich mit den planerischen Grundlagen, dem Umgang mit Nutzungskonflikten und den rechtlichen Rahmenbedingungen einer unterirdischen Raumplanung (Teilvorhaben 2). Unter Zugrundelegung der Erkenntnisse des Teilvorhabens 1 (Geologische Daten) werden die Herausforderungen für die vorsorgende und koordinierende Steuerung von Untergrundnutzungen untersucht. Im Mittelpunkt steht die Frage, ob mit dem bestehenden Instrumentarium der oberirdischen Raumplanung auch das Konzept einer untertägigen Raumplanung verfolgt werden kann. Daran schließt sich die Frage an, welche Anpassungen notwendig sind, um den Herausforderungen einer untertägigen Planung adäquat begegnen zu können. Ausgehend von der Erkenntnis, dass die Vielfalt der Untergrundnutzungen vor dem Hintergrund der energie- und klimapolitischen Ziele der Bundesregierung weiter steigen wird, werden im Bericht zunächst die planerischen Grundlagen ermittelt und dargestellt. Sodann erfolgt eine Entwicklung von Lösungsansätzen zum Umgang mit potenziell bestehenden Nutzungskonflikten, aufbauend auf der Analyse von schutzgutbezogenen Kriterien und materiellinhaltlichen Anforderungen. Im Rahmen der rechtlichen Analyse werden die Instrumente einer vor- und nachsorgenden Steuerung sowie das Zusammenwirken von Raumordnungs- und Fachplanungsrecht untersucht. Bestandteil der rechtlichen Prüfung ist auch die mögliche Einführung eines Bundesspeicherplans. Abschließend werden planerische und rechtliche Handlungsempfehlungen vorgestellt.
Quelle: www.umweltbundesamt.de
title: Music and Video Gaming during Breaks
title: Influence on Habitual versus Goal-Directed Decision Making
titleType: Subtitle
Creators: name: Liu, Shuyan
name: Schad, Daniel J.
name: Kuschpel, Maxim S.
name: Rapp, Michael A.
name: Heinz, Andreas
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Different systems for habitual versus goal-directed control are thought to underlie human decision-making. Working memory is known to shape these decision-making systems and their interplay, and is known to support goal- directed decision making even under stress. Here, we investigated if and how decision systems are differentially influenced by breaks filled with diverse everyday life activities known to modulate working memory performance. We used a within-subject design where young adults listened to music and played a video game during breaks interleaved with trials of a sequential two-step Markov decision task, designed to assess habitual as well as goal-directed decision making. Based on a neurocomputational model of task performance, we observed that for individuals with a rather limited working memory capacity video gaming as compared to music reduced reliance on the goal-directed decision-making system, while a rather large working memory capacity prevented such a decline. Our findings suggest differential effects of everyday activities on key decision-making processes.
Analysis of the role of SHIP2 in the regulation of preadipocyte proliferation and differentiation by PDGF
Creators: name: Artemenko, Yulia
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Biology, Cell.
subject: Chemistry, Biochemistry.

description: Obesity, coupled with inadequate proliferation and/or differentiation of preadipocytes, favours development of adipose tissue dysfunction, characterized by hypertrophied, inflamed, and insulin-resistant adipocytes that predispose to type 2 diabetes and cardiovascular disease. Platelet-derived growth factor (PDGF) promotes proliferation and inhibits differentiation of preadipocytes, and thus might be relevant to preadipocyte fate and adipose tissue function. I hypothesized that SH2 domain-containing inositol 5-phosphatase 2 (SHIP2) modulates both proliferation and differentiation of preadipocytes by mediating PDGF signalling in these cells. Two principal pathways regulating cell proliferation are PI3K/PI(3,4,5)P3/Akt and Shc/Ras/ERK1/2. SHIP2 is important for proliferation likely due to its ability to dephosphorylate PI(3,4,5)P3 and associate with Shc in response to PDGF. Indeed, overexpression of wild-type SHIP2 inhibits 3T3-L1 preadipocyte proliferation; however, the underlying mechanisms are unclear. My first objective was to determine the role of regulatory regions of SHIP2 for its anti-proliferative action. PKC inhibition attenuated PDGF-stimulated SHIP2 tyrosine phosphorylation and Shc association. In addition, disruption of the SH2 domain, the NPAYY motif, or a novel PDGF-responsive phosphorylation site, Thr958, reduced SHIP2 tyrosine phosphorylation and/or Shc association, but neither altered the anti-proliferative effect of SHIP2. In contrast, inactivation of the 5-phosphatase domain potentiated the ability of SHIP2 to inhibit preadipocyte proliferation. This effect was explained by attenuated PDGF signalling caused by a decrease in receptor levels. My second objective was to characterize the negative effect of PDGF on adipocyte differentiation, and to determine the role of SHIP2 in this process. In 3T3-L1 preadipocytes, pro-adipogenic insulin stimulates production of PI(3,4,5)P3 only, whereas PDGF generates PI(3,4,5)P3 and PI(3,4)P2, suggesting activation of a 5-phosphatase. PDGF, but not insulin, leads to SHIP2 tyrosine phosphorylation and Shc association, suggesting that SHIP2 might mediate the anti-adipogenic action of PDGF. I established that PDGF impaired late markers of adipogenesis, and did not inhibit the required exit from the mitotic clonal expansion phase. Overexpression of catalytically inactive, dominant-negative SHIP2 accelerated differentiation and attenuated the anti-adipogenic effect of PDGF. Overall, this study suggests that SHIP2 mediates PDGF signalling in preadipocytes, thereby affecting both proliferation and differentiation, two distinct processes modulated by PDGF in opposite directions.
Development of polymeric foam materials with improved mechanical and acoustic properties
Creators: name: Fu, Jin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Engineering, Mechanical.

description: This thesis addresses the processing, morphology, mechanical properties, and acoustic properties of new polymeric foam materials. A batch foaming process, a rotational mold foaming process and a constrained mold foaming process were designed and applied in the producing of polymeric foams. Microcellular closed cell polymethyl-methacrylate (PMMA) foams were produced using the batch foaming process. The foam morphologies and mechanical properties such as elastic modulus, tensile strength and elongation at break were investigated by varying the foaming parameters. The PMMA microcellular foam showed superior mechanical properties in tensile strength and elongation at break over conventional foams. Nanoclay was used as reinforcement filler and a nucleation agent for PMMA in the batch foaming process. The nanoclay affected the foaming behavior and enhanced the mechanical properties of the microcellular PMMA foams. The PMMA nanocomposite foam with 0.5 wt % nanoclay exhibited optimized mechanical properties. Fine celled Polypropylene (PP) and low density Polyethylene (LDPE) foams were also produced using the rotational mold foaming. The processing parameters such as the particle sizes and processing time were important parameters in this process. The obtained PP foam exhibited a greatly improved energy absorption capacity. Opened cell PMMA foams were produced using a particulate leaching/gas foaming method for acoustic absorption applications. The foam morphology i.e. porosity and cell sizes were independently controlled by altering the processing settings. Consequently, the acoustic performance of the foams was manipulated. Finite element analysis was then employed to predict the macroscopic properties of polymeric foams correlated to their microstructure. The predicted elastic responses of both opened cell and closed cell foams showed great agreement with experimental results.