cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A new model of collaborative research: experiences from one of Australia’s NHMRC Partnership Centres for Better Health
Creators: name: Wutske, Sonia
name: Redman, Sally
name: Bauman, Adrian
name: Hawe, Penelope
name: Shiell, Alan
name: Thackway, Sarah
name: Wilson, Andrew
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems
classificationCode: 4206
subject: Public health

description: There is often a disconnection between the creation of evidence and its use in policy and practice. Cross-sectoral, multidisciplinary partnership research, founded on shared governance and coproduction, is considered to be one of the most effective means of overcoming this research-policy-practice disconnect. Similar to a number of funding bodies internationally, Australia's National Health and Medical Research Council has introduced Partnership Centres for Better Health: a scheme explicitly designed to encourage coproduced partnership research. In this paper, we describe our experiences of The Australian Prevention Partnership Centre, established in June 2013 to explore the systems, strategies and structures that inform decisions about how to prevent lifestyle-related chronic disease. We present our view on how the Partnership Centre model is working in practice. We comment on the unique features of the Partnership Centre funding model, how these features enable ways of working that are different from both investigator-initiated and commissioned research, and how these ways of working can result in unique outcomes that would otherwise not have been possible. Although not without challenges, the Partnership Centre approach addresses a major gap in the Australian research environment, whereby large-scale, research-policy-practice partnerships are established with sufficient time, resources and flexibility to deliver highly innovative, timely and accessible research that is of use to policy and practice.
MUALLIF DISKURSIV SHAXSINING SARLAVHA VA EPIGRAF VOSITASIDA NAMOYON BO'LISHI
Creators: name: Abdulloyeva, Kamola
Publisher: name: Zenodo
Year: 2024

description: Badiiy matnni kognitiv tahlil etish alohida e’tiborni talab qilib, asarning eng muhim detallari sanaluvchi sarlavha va epigraf tadqiqi eng muhim jihatlaridan biri sanaladi. Zero, muallif diskursiv shaxsi aynan sarlavha hamda epigraf vositasida nafaqat o‘zining individual dunyo manzarasi va qarashlarini namoyon etishi, balki vaziyatga munosabatini ham aks ettirishi mumkin. Shuningdek, sarlavha va epigraf badiiy matn mazmuni xususida ilk tasavvur hosil qilishda ham ahamiyatli sanalib, e’tiborni tortish va mushohadaga chorlash kabi o‘ziga xosliklarga ega hisoblanadi. Quyida keltirilgan badiiy matnlar tahlili ushbu xususiyatlarni ochib berishga xizmat qiladi.
Synthesis of Quinazolinone Based Spirocyclopropanes via [3 + 2] Cycloaddition Reaction: In Silico Anti-Tubercular Molecular Docking Studies and ADME Prediction
Creators: name: Allaka, Bhargava Sai
name: Kanchrana, Madhu
name: Gamidi, Rama krishna
name: Basavoju, Srinivas
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: A highly efficient cascade annulation approach is developed for the synthesis of novel quinazolinone-based spirocyclopropanes via three-component [3 + 2] cycloaddition reaction with aldehydes, tosylhydrazide and quinazolinyl chalcones. The reaction features the formation of two C–C bonds and three stereogenic centers. A variety of highly functionalized spirocyclopropyl quinazolinones were obtained in good yields under mild reaction conditions. Furthermore, in silico anti-tubercular (anti-TB) molecular docking studies were performed for the generated compounds against three Mycobacterium tuberculosis proteins with PDBID: 1DF7, 1P44 and 4TZK. ADME prediction were evaluated for the drug like properties of the synthesized compounds.
Investigation of Molecular Structure, Topological and Molecular Docking Studies of a Novel Anticancer Drug Pacritinib
Creators: name: Elangovan, N.
name: Alzahrani, Abdullah Y.
name: Ajithkumar, G.
name: J, Rajimon K.
name: Thomas, Renjith
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Biochemistry
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The B3LYP/cc-pVDZ basis set was used to optimize the best results of Pacritinib whose systematic name is (E)- 44-(2-(pyrrolidin-1-yl) ethoxy) −6,11- dioxa-3- aza-2(4,2)- pyrimidine −1,4 (1,3)-dibenzenacyclododecaphan-8-ene (MJ). The NBO analysis confirm the highest stabilization energy 55.36 kcal/mol, from bonding LP (1)–N13 to anti-bonding π*(N10 - C11). The ELF, LOL, ALIE, and RDG, analysis was done by using Multiwfn software, and confirms the localization and delocalization electrons. The thermodynamical properties and electron density were calculated with help of Gaussian-16w software. Analyses of NLO parameters, MEP, UV-vis, and HOMO-LUMO were performed using five different solvents (chloroform, water, acetonitrile, ethanol and DMSO). Docking study was done, against 5C5S protein and we identify the protein-ligand interaction, the best binding score is −6.64 kcal/mol.
Sustainable, Scalable, and One-Pot Synthesis of Isoxazol-5(4H)-One and 1,2,4-Triazoloquinazolinone Derivatives Using a Natural Deep Eutectic Solvent
Creators: name: Khoshdel, Meysam Alipour
name: Mazloumi, Masoumeh
name: Zabihzadeh, Mehdi
name: Shirini, Farhad
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: In this work, a sustainable and efficient procedure for the synthesis of isoxazol-5(4H)-one and 1,2,4-triazoloquinazolinone derivatives via multi-component reactions using a natural deep eutectic solvent prepared from choline chloride and glutamic acid is described. The proposed methodology is capable of providing the requested products during acceptable reaction times in good to high yields under green conditions. The utilization of affordable, readily available, non-toxic, and bio-compatible reagents for the synthesis of the catalyst, a straightforward procedure for the preparation of the catalyst and products, simple work-up, and applicability in large-scale synthesis are the prominent features of this method. Also, the catalyst can be recovered easily and reused several times in the studied reactions.
Synthesis, Biological Evaluation, DFT Calculations and Molecular Docking of 5-Arylidene-Thiazolidine-2,4-Dione Derivatives
Creators: name: Zine, Yasmine
name: Krid, Adel
name: Boulcina, Raouf
name: Harakat, Dominique
name: Robert, Anthony
name: Bensouici, Chawki
name: Debache, Abdelmadjid
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Computational Biology

description: A simple and rapid procedure is developed for the synthesis of 5-arylidene-thiazolidine-2,4-dione derivatives by the Knoevenagel reaction between a variety of aromatic aldehydes and thiazolidine-2,4-dione, catalyzed by N,N-dimethylaminopyridine. The reactions were carried out without solvent giving excellent yields of the expected products. The antioxidant activity of all the molecules prepared was evaluated and two of them gave encouraging results. In addition, an extensive theoretical study was carried out such as density functional theory (DFT) calculations, theoretical predictions of biological activities and molecular docking.
Materials Genome in Action: Identifying the Performance Limits of Physical Hydrogen Storage
Creators: name: Thornton, AW
name: Simon, CM
name: Kim, J
name: Kwon, O
name: Deeg, KS
name: Konstas, K
name: Pas, SJ
name: Hill, MR
name: Winkler, David
name: Haranczyk, M
name: Smit, B
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences
classificationCode: 3406
subject: Physical chemistry
classificationCode: 40
subject: Engineering

description: The Materials Genome is in action: the molecular codes for millions of materials have been sequenced, predictive models have been developed, and now the challenge of hydrogen storage is targeted. Renewably generated hydrogen is an attractive transportation fuel with zero carbon emissions, but its storage remains a significant challenge. Nanoporous adsorbents have shown promising physical adsorption of hydrogen approaching targeted capacities, but the scope of studies has remained limited. Here the Nanoporous Materials Genome, containing over 850 000 materials, is analyzed with a variety of computational tools to explore the limits of hydrogen storage. Optimal features that maximize net capacity at room temperature include pore sizes of around 6 Å and void fractions of 0.1, while at cryogenic temperatures pore sizes of 10 Å and void fractions of 0.5 are optimal. Our top candidates are found to be commercially attractive as "cryo-adsorbents", with promising storage capacities at 77 K and 100 bar with 30% enhancement to 40 g/L, a promising alternative to liquefaction at 20 K and compression at 700 bar.
Supplementary document for Cold damping of levitated optically coupled nanoparticles - 6443275.pdf
Creators: name: Liska, Vojtech
name: Zemankova, Tereza
name: Svak, Vojtech
name: Jakl, Petr
name: Jezek, Jan
name: Branecky, Martin
name: Simpson, Stephen
name: Zemanek, Pavel
name: Brzobohaty, Oto
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental information
Synthesis, Characterization, and Catalytic Application of SnP2O7 for the Highly Efficient Synthesis of Xanthene Derivatives
Creators: name: Merroun, Youssef
name: Chehab, Soukaina
name: Hallaoui, Achraf El
name: Guedira, Taoufiq
name: Boukhris, Said
name: Ghailane, Rachida
name: Souizi, Abdelaziz
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: This study introduces a mono-ammonium phosphate-based heterogeneous catalyst that possesses characteristics of simplicity, reusability, and recoverability, making it well-suited for multicomponent reactions. The prepared catalyst underwent comprehensive characterization using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) patterns, scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). Employing this catalyst in a one-pot multicomponent approach, it becomes possible to synthesize xanthene derivatives efficiently. The results showcase the impressive performance of the novel SnP2O7, which acts as a heterogeneous catalyst in traditional reactions, leading to the desired products with yields ranging from good to excellent and within a short reaction time. Notably, SnP2O7 exhibits remarkable stability in its catalytic activity, enabling its use for up to five cycles without experiencing a significant decrease in yield.
Take a Hike
Creators: Musante, Glenna B.
Publisher: name: University of Alberta Library
Year: 2015

There was a time when shopping for a pair of hiking socks was a simple matter. For warm weather hiking, you would probably pick a thin athletic sock made from cotton or synthetic fibers. If it was winter, you would buy a thick pair of socks, probably

wool, and hope they wouldn’t be scratchy.

Meanwhile, if bulk from the sock caused your boot to feel too tight, you would loosen the ties. In addition, before going for a long hike, a serious hiker would probably wrap his or her heels, bunions, and maybe even toes with waterproof first aid tape to help prevent blisters, or throw some lamb’s wool into the heel well or boot toe for good measure.

Blisters, after all, were an inevitable part of any hike. But that has changed.
Xiong Shili on Why Reality Cannot Be Sought Independent of Phenomena
Creators: name: Makeham, John
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2017, Springer Science+Business Media Dordrecht.
In China, Xiong Shili(1885–1968) is typically regarded as one of the most important Chinese philosophers of the twentieth century. The focus of this paper is Xiong’s monistic ontology and draws its findings principally from the 1932 literary edition of his New Treatise on Nothing but Consciousness (Xin weishi lun). Xiong’s New Treatise is the first substantive attempt to respond to the modernist challenge of providing Chinese philosophy with ‘system,’ and he did this in the form of an ontology. The New Treatise consists of an interpretive summary and discussion of key Yogācāra teachings that feature in Cheng weishi lun; a sustained critique of views Xiong attributes to the sixth-century Yogācāra master Dharmapāla; and a synthesis of Yogācāra thought with ideas derived from Madhyamaka Buddhism, various Sinitic traditions of Buddhism, the Book of Change, Laozi and Zhuangzi, and from Chinese Neo-Confucian thinkers associated with the Lu-Wang wing of Neo-Confucian philosophy, as well as Zhu Xi. Xiong was very much a syncretist. I seek to explain why Xiong insisted that reality (shiti[*tattva]) cannot be sought independent of phenomena despite his also claiming that phenomena are not real. The first and major part of the paper introduces Xiong’s critique of Yogācāra accounts of consciousness. The second part introduces his understanding of the doctrine of emptiness. I also trace the connection between Xiong’s understanding and how the concept of emptiness was understood in Tathāgatagarbha school of Sinitic Buddhism. I do not address the Confucian elements in his thought—the Buddhist elements are complex enough.
The Novel Catalyst (Hypogallic Acid-Based Deep Eutectic Solvent) for Preparation of the New Compounds (Pyrano[2,3-d]Pyrimidines)
Creators: name: Monem, Arezo
name: Habibi, Davood
name: Goudarzi, Hadis
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Marine Biology
subject: Hematology

description: A novel Deep Eutectic Solvent (MTPPBr/HGA-DES) was prepared by a mixture of methyl triphenylphosphonium bromide (MTPPBr) and hypogallic acid (HGA: 2,3-dihydroxybenzoic acid). The eutectic point phase diagram showed that the one mole of MTPPBr to two moles of HGA is the best mole ratio for the synthesis of a novel DES. Then, MTPPBr/HGA-DES was characterized by the FT-IR, TGA/DTA, densitometer, eutectic points, and 1H NMR techniques, and used as a novel catalyst for the green synthesis of new pyrano[2,3-d]pyrimidines 2(a-j) via a one-pot four-component condensation reaction of 4-hydroxycoumarin, barbituric acid, morpholine and benzaldehydes at 80 °C in solvent-free conditions.
Twelve photographs : Canadian Pacific Cruise
Creators: name: Canadian Pacific Steamships
name: Associated Screen News Limited
name: Crawford, Lawrence
Publisher: name: Montreal : Associated Screen News Limited
Year: 2018

description: Three envelopes formerly housing photographs from cruises to Hong Kong, Yokohama and Tokyo, and Manila. Assembled by Lawrence Crawford, orchestra leader on the Canadian Pacific second Empress of Japan, Princess Louise, and Princess Alice.
Tissue growth and tumorigenesis in Drosophila: cell polarity and the Hippo pathway
Creators: name: Richardson, Helena
name: Portela-Esteban, Marta
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology

description: Cell polarity regulation is critical for defining membrane domains required for the establishment and maintenance of the apical-basal axis in epithelial cells (apico-basal polarity), asymmetric cell divisions, planar organization of tissues (planar cell polarity), and the formation of the front-rear axis in cell migration (front-rear polarity). In the vinegar fly, Drosophila melanogaster, cell polarity regulators also interact with the Hippo tissue growth control signaling pathway. In this review we survey the recent Drosophila literature linking cell polarity regulators with the Hippo pathway in epithelial tissue growth, neural stem cell asymmetric divisions and in cell migration in physiological and tumorigenic settings.
title: The 2016 eastern Bering Sea continental shelf bottom trawl survey : results for commercial crab species.
title: Results for commercial crab species
titleType: AlternativeTitle
Creators: name: Daly, Benjamin
name: Armistead, Claire E.
name: Foy, Robert James
Publisher: name: U.S. Department of Commerce, National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Alaska Fisheries Science Center
Year: 2016
Subjects: subject: Crab fisheries--Alaska--Bering Sea Coast--Management.

description: The eastern Bering Sea bottom trawl survey has been conducted annually since 1975 by the Resource Assessment and Conservation Engineering Division of the Alaska Fisheries Science Center, National Marine Fisheries Service. The purpose of this survey is to collect data on the distribution and abundance of crab, groundfish, and other benthic resources in the eastern Bering Sea. These data are used to estimate population abundances for the management of commercially important species in the region. This document includes the time series of results from 1975 to the present. In 2016, 375 standard stations were sampled on the eastern Bering Sea shelf.
Tissue growth and tumorigenesis in Drosophila: cell polarity and the Hippo pathway
Creators: name: Richardson, Helena
name: Portela-Esteban, Marta
Publisher: name: La Trobe
Year: 2022

description: Cell polarity regulation is critical for defining membrane domains required for the establishment and maintenance of the apical-basal axis in epithelial cells (apico-basal polarity), asymmetric cell divisions, planar organization of tissues (planar cell polarity), and the formation of the front-rear axis in cell migration (front-rear polarity). In the vinegar fly, Drosophila melanogaster, cell polarity regulators also interact with the Hippo tissue growth control signaling pathway. In this review we survey the recent Drosophila literature linking cell polarity regulators with the Hippo pathway in epithelial tissue growth, neural stem cell asymmetric divisions and in cell migration in physiological and tumorigenic settings.
Responsibilities, tensions and ways forward: parents’ perspectives on children’s sexuality education
Creators: name: Robinson, Kerry H
name: Smith, Elizabeth
name: Davies, Cristyn
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 39
subject: Education
classificationCode: 3901
subject: Curriculum and pedagogy
classificationCode: 3904
subject: Specialist studies in education
classificationCode: 4206
subject: Public health

description: Children’s sexuality education continues to be plagued with tensions and controversies. In consequence, children’s access to sexuality education is severely compromised, especially in terms of the time dedicated to this topic, the content addressed, how it is taught and by whom. Based on a study of 342 Australian parents of primary school aged children we explore: (i) parents’ perceptions of the relevance and importance of sexuality education to their primary school aged children and the discourses that inform their perspectives; (ii) parents’ views on who should be responsible for the sexuality education of young children; (iii) whether there are certain aspects of sexuality education considered more appropriate for the family to address with children; and (iv) what the implications of these findings are for sexuality education policy and practice in Australian primary schooling. Despite the controversial nature of the topic, the majority of parents in this study believed sexuality education was relevant and important to primary school children and that it should be a collaborative approach between families and schools. However, some parents/carers acknowledged that while that they believed that some topics should only be addressed at home they also indicated that this often does not happen.
Emotion_SupplementalInformation – Supplemental material for Emotion and judgments of scientific research
Creators: name: Drummond, Caitlin
name: Fischhoff, Baruch
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: Science Policy

description: Supplemental material, Emotion_SupplementalInformation for Emotion and judgments of scientific research by Caitlin Drummond and Baruch Fischhoff in Public Understanding of Science
Alaska and the Yukon : Princess service 1939
Creators: name: Canadian Pacific Railway. British Columbia Coast Steamship Service
name: Crawford, Lawrence
Publisher: name: The University of British Columbia
Year: 2018

description: Pamphlet advertising the sailing dates and fares for Alaska and the Yukon for summer 1939, including deck plans of the Princess ships. Also includes a manuscript note about extra money. Assembled by Lawrence Crawford, orchestra leader on the Canadian Pacific second Empress of Japan, Princess Louise, and Princess Alice.
Theoretical Investigation on Solvents Effect in Molecular Structure (TD-DFT, MEP, HOMO-LUMO), Topological Analysis and Molecular Docking Studies of N-(5-((4-Ethylpiperazin-1-yl)Methyl)Pyridin-2-yl)-5-Fluoro-4-(4-Fluoro-1-Isopropyl-2-Methyl-1H-Benzo[d] Imidazol-6-yl) Pyrimidin-2-Amine
Creators: name: Elangovan, N.
name: Sowrirajan, S.
name: Arumugam, Natarajan
name: Rajeswari, B.
name: Mathew, Shanty
name: Priya, C. Geetha
name: Venkatraman, B. R.
name: Mahalingam, Sakkarapalayam M.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Space Science
Physical Sciences not elsewhere classified
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: B3LYP/cc-pVDZ generated the best N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d] imidazol-6-yl) pyrimidin-2-amine (TA) results. The NBO study shows that the LP (1) N16 to π*(C17-N19) has the highest stabilization energy at 53.86 kcal/mol. Electron localization and delocalization areas are confirmed by wavefunction studies. The Gaussian-16w software establishes thermodynamic properties for a titled compound which is confirmed by various solvents. The frontier molecular orbital studies we confirmed by gas phase have the highest bond gap value which is 4.02 eV. The titled compound nitrogen is the nucleophilic attack (blue color) and oxygen is the electrophilic attack (red color), which is confirmed by MEP study. In non-linear optical (NLO) study water solvent shows the highest dipole moment activity, due to the solvent’s interaction the gas phase dipole moment is lower. The docking study showed the greatest binding affinity score of −5.28 kcal/mol.
Tolerating dissimilar other when primed with death: neural evidence of self-control engaged by interdependent people in Japan
Creators: name: Yanagisawa, Kuniaki
name: Kashima, Emiko
name: Moriya, Hiroki
name: Masui, Keita
name: Furutani, Kaichiro
name: Yoshida, Hiroshi
name: Ura, Mitsuhiro
name: Nomura, Michio
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 3209
subject: Neurosciences
subject: FOS: Clinical medicine
classificationCode: 52
subject: Psychology
subject: FOS: Psychology
classificationCode: 5202
subject: Biological psychology
classificationCode: 5203
subject: Clinical and health psychology
classificationCode: 520505
subject: Social psychology

description: Mortality salience (MS) has been shown to lead to derogation of others with dissimilar worldviews, yet recent research has shown that Asian-Americans who presumably adopt an interdependent self-construal (SC) tend to reveal greater tolerance after MS induction. In the present study, we demonstrated that Japanese individuals who are high on interdependent SC indeed show greater tolerance toward worldview-threatening other in the MS (vs control) condition, thus replicating the prior research. Extending this research, we also found that interdependent people's tolerance toward worldview-threatening other was mediated by increased activity in the right ventrolateral prefrontal cortex in the MS condition. These data suggested that when exposed to death-related stimuli, highly interdependent individuals may spontaneously activate their neural self-control system which may serve to increase tolerance toward others.
RilstoneTable_S1 – Supplemental material for A Pilot Study of Flat and Circadian Insulin Infusion Rates in Continuous Subcutaneous Insulin Infusion (CSII) in Adults with Type 1 Diabetes (FIRST1D)
Creators: name: Siân Rilstone
name: Reddy, Monika
name: Oliver, Nick
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: Medicine
subject: 111199 Nutrition and Dietetics not elsewhere classified

description: Supplemental material, RilstoneTable_S1 for A Pilot Study of Flat and Circadian Insulin Infusion Rates in Continuous Subcutaneous Insulin Infusion (CSII) in Adults with Type 1 Diabetes (FIRST1D) by Siân Rilstone, Monika Reddy and Nick Oliver in Journal of Diabetes Science and Technology
Synthesis of New 2-Pyridinone and 2-Iminochromene Derivatives Bearing Biologically Active Pyrrole Moiety as Expected Antibacterial and Antifungal Agents
Creators: name: Al-Harbi, Reem A. K.
name: El-Sharief, Marwa A. M. Sh.
name: Abbas, Samir Y.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: In an attempt to discover new antimicrobial drugs, new 2-pyridinone and 2-iminochromene derivatives bearing biologically active pyrrole nucleus were designed and synthesized. The pyridin-2-one derivatives were synthesized via ring closure of 2-cyano-N'-((1-methyl-1H-pyrrol-2-yl)methylene)acetohydrazide by acetylacetone or 2-arylidenemalononitriles. The 2-iminochromene derivatives were obtained in high yields through the cyclocondensation reaction of 2-cyano-N'-((1-methyl-1H-pyrrol-2-yl)methylene)acetohydrazide with o-hydroxy aldehyde derivatives (salicyaldehyde derivatives, 2-hydroxy-1-naphthaldehyde and 7-hydroxy-chromone-6-carboxaldehyde derivative). The antibacterial and antifungal properties of all synthesized compounds were evaluated. All tested compounds displayed weak activities toward the G + ve bacteria (S. aureus) and G –ve bacteria (E. coli and P. vulgaris). The polycyclic benzo[f]chromene derivative 7 showed weak activity toward both G + ve and G –ve bacteria.
Progetto Per Lo Sviluppo Della Dual Career Nella Scuola Secondaria Di Secondo Grado Italiana
Creators: name: Mascia Migliorati
name: Maulini, Claudia
name: Isidori, Emanuele
Publisher: name: Zenodo
Year: 2016
Subjects: dual-career, studente-atleta, scuola secondaria, associazioni/società sportive.
dual-career, student-athlete, secondary school, sport associations.

description: Il progetto prevede la costruzione di un percorso di dual-career per gli studenti-atleti che frequentano la scuola secondaria di secondo grado. Coinvolgerà attivamente il contesto scolastico e sportivo al fine di promuovere lo sviluppo globale dei giovani atleti e di trovare un equilibrio tra la formazione sportiva e l’educazione.

La metodologia di intervento, partendo da una fase di sensibilizzazione e formazione di tutti gli attori coinvolti secondo un approccio olistico e sistemico, prevede la costruzione di un percorso formativo-educativo personalizzato per lo studente-atleta, avvalendosi di specifiche strategie didattiche e organizzative e di attività di supporto di tutoring e counseling, unitamente all’ausilio di una piattaforma di apprendimento e-learning.

The project involves the construction of a dual-career path for student-athletes who attend secondary school degree. The project actively involves the school and sports environment in order to promote the global development of young athletes and to find a balance between sports training and education.

The methodology of intervention, starting from a phase of awareness and training of all actors involved in a holistic and systemic approach, considers the construction of a personalized educational process for the student-athlete using specific teaching and organizational strategies and tutoring and counseling  support activities together with the aid of an e-learning platform.
Reactivity and Structural Investigation of Tetrahydroneoprzewaquinone A as an Anti-Inflammatory Agent: An Experimental and Molecular Modeling Perspective
Creators: name: Ejiofor, Emmanuel U.
name: Ukpanukpong, Richard U.
name: Agwamba, Ernest C.
name: Benjamin, Innocent
name: Ahukwe, Eze F.
name: Maxwell, Kube T.
name: Edet, Uwem O.
name: Bassey, Ini U.
name: Muozie, Maryjane C.
name: Manicum, Amanda-Lee Ezra
name: Louis, Hitler
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: This intriguing study aimed to explore the reactivity and structural investigation of (3R,3′R)-2,2′,3,3′-tetrahydroneoprzewaquinone A (THNPQ A) as a potential anti-inflammatory agent. Substantially, the electronic properties were investigated using LanL2DZ, 6-311++G (d,p), and STO-3G basis sets, with electronegativity values of 7.9816, 6.3038, and 5.0166 eV, respectively. The natural bond orbital (NBO) analysis calculations of optimization energies revealed that LanL2DZ had the highest stabilization energy (526.65 kcal/mol) for the interaction between πC8-C9 and πC3-C4. Regarding nonlinear optical (NLO) properties, 6-311++G (d,p) exhibited the highest averaged polarizability and first-order hyperpolarizability values, while the polarizability anisotropies Δtotal followed the order 6-311++G (d,p) (65.2054 a.u.) > LanL2DZ (42.8782 a.u.) > STO-3G (29.9349 a.u.). Analysis of the density of states (DOS) and orbital contribution showed that 6-311++G (d,p) had the highest density peaks at both the highest occupied molecular orbital (HOMO) (–0.5 a.u.) and the lowest unoccupied molecular orbital (LUMO) (0.00 a.u.). The condensed dual descriptors indicated minimal variations in the fA– and fA+ values, with an increase in ΔfA, fA–, and fA+ values following the order STO-3G > LanL2DZ > 6-311++G (d,p). The sites for potential nucleophilic attack were identified as O11, O12, O36, and O37, which exhibited the highest values with the STO-3G basis set. Empirical evidence from in vitro inhibition assays unequivocally validates the potent anti-inflammatory activity of THNPQ A. Particularly noteworthy is its exceptional binding affinity, surpassing that of diclofenac. By establishing conventional hydrogen bonds with the glycine of COX-I and histidine of COX-II, THNPQ A exhibits remarkable potential as an effective agent for combating inflammation. These findings boldly emphasize the promising therapeutic prospects of THNPQ A in the field of anti-inflammatory treatment, positioning it as a compelling candidate for further investigation and development.
Screening mitochondrial DNA sequence variation as an alternative method for tracking established and outbreak populations of Queensland fruit fly at the species southern range limit
Creators: name: Blacket, Mark J
name: Malipatil, Mallik
name: Semeraro, Linda
name: Gillespie, Peter S
name: Dominiak, Bernie C
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3103
subject: Ecology
classificationCode: 3104
subject: Evolutionary biology
classificationCode: 3105
subject: Genetics
classificationCode: 41
subject: Environmental sciences
classificationCode: 4101
subject: Climate change impacts and adaptation
classificationCode: 4102
subject: Ecological applications

description: Understanding the relationship between incursions of insect pests and established populations is critical to implementing effective control. Studies of genetic variation can provide powerful tools to examine potential invasion pathways and longevity of individual pest outbreaks. The major fruit fly pest in eastern Australia, Queensland fruit fly Bactrocera tryoni (Froggatt), has been subject to significant long-term quarantine and population reduction control measures in the major horticulture production areas of southeastern Australia, at the species southern range limit. Previous studies have employed microsatellite markers to estimate gene flow between populations across this region. In this study, we used an independent genetic marker, mitochondrial DNA (mtDNA) sequences, to screen genetic variation in established and adjacent outbreak populations in southeastern Australia. During the study period, favorable environmental conditions resulted in multiple outbreaks, which appeared genetically distinctive and relatively geographically localized, implying minimal dispersal between simultaneous outbreaks. Populations in established regions were found to occur over much larger areas. Screening mtDNA (female) lineages proved to be an effective alternative genetic tool to assist in understanding fruit fly population dynamics and provide another possible molecular method that could now be employed for better understanding of the ecology and evolution of this and other pest species.
THE PHILOSOPHY OF HOSPITALITY IN UZBEKISTAN: TRADITIONAL CULTURE AND INNOVATIVE INSTRUMENTS FOR CREATING UNIQUE GUEST'S EXPERIENCE
Creators: name: Ulmasova, Bahora
Publisher: name: Zenodo
Year: 2024

description: Hospitality has become an important part of tourism industry that helps to grow the economy of countries. It is a complex sector and it includes different services such as providing guests with accommodation, food and beverages and wonderful experiences. The aim of the study is to explore the role of innovative instruments, hospitality customs and traditional culture on create extraordinary guests’ experience. For collecting data, a mixed-method design was used, for qualitative method we analyzed more than 20 articles, journals and previous studies related to this topic for making a better understanding. The papers were taken from different internet sources, and Web of Science, Research Gate, Google Scholar and etc. For quantitative questions multiple choice questions with open-ended questions used for understanding visitor’s suggestions, issues and their memorable experiences. In this survey both local and international travelers, hospitality staff, and students from foreign countries have participated. According to the results of survey, we can see that, almost 62% of travelers who experienced the hospitality services are satisfied with the facilities provided by hospitality staff. 55.4% of visitors are likely to suggest Uzbekistan as a travel destination that focuses on traditional culture and hospitality.
Monte Finocchito and Eloro pottery production: new evidence through technological studies and material analysis
Creators: name: Raudino, Anna
name: Tykot, R
name: Vianello, A
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 43
subject: History, heritage and archaeology
classificationCode: 4301
subject: Archaeology
classificationCode: 4303
subject: Historical studies

description: This paper discusses the use of non-destructive portable X-ray fluorescence (pXRF) to distinguish sources of variation in 8th Century BC Greek and Sicilian ceramics. The project comprises an element of my PhD study through La Trobe University, concerning Hellenic colonies established from the eighth century BC in the south of Italy, and on Sicily in particular. This specific case study looks at the relationships established between the indigenous site of Monte Finocchito and the Greek settlement of Heloros, both located in south-eastern Sicily. The results demonstrate the usefulness of the pXRF technique for detecting material variations which are not readily apparent using traditional visual analysis during fieldwork.
The influence of journal submission guidelines on authors' reporting of statistics and use of open research practices
Creators: name: Giofrè, David
name: Cumming, Geoffrey
name: Fresc, Luca
name: Boedker, Ingrid
name: Tressoldi, Patrizio
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 46
subject: Information and computing sciences
classificationCode: 4610
subject: Library and information studies
classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: From January 2014, Psychological Science introduced new submission guidelines that encouraged the use of effect sizes, estimation, and meta-analysis (the "new statistics"), required extra detail of methods, and offered badges for use of open science practices. We investigated the use of these practices in empirical articles published by Psychological Science and, for comparison, by the Journal of Experimental Psychology: General, during the period of January 2013 to December 2015. The use of null hypothesis significance testing (NHST) was extremely high at all times and in both journals. In Psychological Science, the use of confidence intervals increased markedly overall, from 28% of articles in 2013 to 70% in 2015, as did the availability of open data (3 to 39%) and open materials (7 to 31%). The other journal showed smaller or much smaller changes. Our findings suggest that journal specific submission guidelines may encourage desirable changes in authors' practices.
Synthesis, Biological Evaluation, and Molecular Docking Investigation of New Series of Azoimino-Sulfathiazole (AIST) Derivatives
Creators: name: Mahmoodi, Nosrat O.
name: Amouee, Fatemeh
name: Nyaki, Hadiseh Yazdani
name: Nahzomi, Hossein Taherpour
name: Ahmadi, Ali
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: Sulfonamides are important compounds with special applications in pharmaceuticals due to their antibacterial and antiparasitic properties, and they are known as sulfa drugs (SDs). In this study, we focused on the multifunctional therapeutic compound sulfathiazole (ST) and investigated its hybridization of imine bonds with various azo compounds. A series of novel azoimino-sulfathiazoles (AIST) was successfully synthesized using a one-pot three-component reaction (3MCR) methodology. Additionally, we reported the design and synthesis of two ST derivatives bound to an azo group in a 3MCR dish. The structure of the newly synthesized AISD after separation and purification was examined and confirmed by TLC, M.P., FT-IR, 1H NMR, and 13C NMR. Furthermore, their cytotoxicity was evaluated via MTT assay. The antibacterial, antioxidant, and anticancer activities of the AISD compounds were assessed using the MTT assay, focusing on the PC-3 human prostate cancer cell line. The results showed good resistance to E. coli and S. aureus, with inhibition zones of 27 and 31 mm, respectively, compared to standard penicillin G. More importantly, certain AIST compounds exhibited superior antibacterial activity compared to penicillin G. To understand the mode of action of the proteins and potential interactions, docking calculations were performed using the target proteins 1FDW, 3FC2, and 5GWK. 5GWK achieved the highest placement score, followed by 1FDW and 3FC2, which showed strong closeness. A detailed analysis of the ligand–protein interactions revealed the strongest interaction with human topoisomerase II alpha (5GWK) as the target protein.
Genotype Imputation to Improve the Cost-Efficiency of Genomic Selection in Farmed Atlantic Salmon
Creators: name: Tsai, Hsin-Yuan
name: Matika, Oswald
name: Edwards, Stefan McKinnon
name: Antolín–Sánchez, Roberto
name: Hamilton, Alastair
name: Guy, Derrick R
name: Tinch, Alan E
name: Gharbi, Karim
name: Stear, Michael
name: Taggart, John B
name: Bron, James E
name: Hickey, John M
name: Houston, Ross D
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 3105
subject: Genetics
classificationCode: 4905
subject: Statistics
subject: FOS: Mathematics

description: Genomic selection uses genome-wide marker information to predict breeding values for traits of economic interest, and is more accurate than pedigree-based methods. The development of high density SNP arrays for Atlantic salmon has enabled genomic selection in selective breeding programs, alongside high-resolution association mapping of the genetic basis of complex traits. However, in sibling testing schemes typical of salmon breeding programs, trait records are available on many thousands of fish with close relationships to the selection candidates. Therefore, routine high density SNP genotyping may be prohibitively expensive. One means to reducing genotyping cost is the use of genotype imputation, where selected key animals (e.g., breeding program parents) are genotyped at high density, and the majority of individuals (e.g., performance tested fish and selection candidates) are genotyped at much lower density, followed by imputation to high density. The main objectives of the current study were to assess the feasibility and accuracy of genotype imputation in the context of a salmon breeding program. The specific aims were: (i) to measure the accuracy of genotype imputation using medium (25 K) and high (78 K) density mapped SNP panels, by masking varying proportions of the genotypes and assessing the correlation between the imputed genotypes and the true genotypes; and (ii) to assess the efficacy of imputed genotype data in genomic prediction of key performance traits (sea lice resistance and body weight). Imputation accuracies of up to 0.90 were observed using the simple two-generation pedigree dataset, and moderately high accuracy (0.83) was possible even with very low density SNP data (~250 SNPs). The performance of genomic prediction using imputed genotype data was comparable to using true genotype data, and both were superior to pedigree-based prediction. These results demonstrate that the genotype imputation approach used in this study can provide a cost-effective method for generating robust genome-wide SNP data for genomic prediction in Atlantic salmon. Genotype imputation approaches are likely to form a critical component of cost-efficient genomic selection programs to improve economically important traits in aquaculture.
KREDIT XIZMATLARI BOZORINI DAVLAT TOMONIDAN TARTIBGA SOLISHDA XORIJIY DAVLATLAR TAJRIBASI
Creators: name: Kurbonov Rustam Radjabovich Termiz davlat muhandislik va agrotexnologiyalar universiteti  Tarmoqlar iqtisodiyoti kafedrasi o'qituvchisi
Publisher: name: Zenodo
Year: 2024

description: Maqolada kredit xizmatlari bozorini davlat tomonidan tartibga solishda xorijiy davlatlar tajribalari haqida bahs yuritiladi. Muallifning e’tiroficha, xorijiy mamlakatlar hukumatlari kredit tashkilotlarini kapitallashtirish va qayta moliyalashtirish orqali ularning likvidligini saqlashda faol ishtirok etadilar
Figure_3._The_pooled_relative_risk_RR_between_cryptosporidiosis_related_to_CD4plus_lymphocyte_counts. – Supplemental material for Cryptosporidium Infection Increases the Risk for Chronic Diarrhea Among People Living With HIV in Southeast Asia: A Systematic Review and Meta-Analysis
Creators: name: Wiwien S. Utami
name: Murhandarwati, Elsa H.
name: Wayan T. Artama
name: Kusnanto, Hari
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, Figure_3._The_pooled_relative_risk_RR_between_cryptosporidiosis_related_to_CD4plus_lymphocyte_counts. for Cryptosporidium Infection Increases the Risk for Chronic Diarrhea Among People Living With HIV in Southeast Asia: A Systematic Review and Meta-Analysis by Wiwien S. Utami, Elsa H. Murhandarwati, Wayan T. Artama and Hari Kusnanto in Asia Pacific Journal of Public Health
title: Data report : 2003 Gulf of Alaska bottom trawl survey.
title: 2003 Gulf of Alaska bottom trawl survey
titleType: AlternativeTitle
Creators: name: Raring, Nate W.
name: Von Szalay, Paul G. ǂq (Paul Gunnar)
name: Martin, Michael Hall
name: Wilkins, Mark E.
name: Shaw, Franklin R.
Publisher: name: U.S. Department of Commerce, National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Alaska Fisheries Science Center
Year: 2016
Subjects: subject: Groundfish fisheries--Catch effort--Alaska--Alaska, Gulf of--Statistics.

description: Scientists of the Groundfish Assessment Program of Alaska Fisheries Science Center's Resource Assessment and Conservation Engineering (RACE) Division conducted the third biennial groundfish assessment survey of the Gulf of Alaska during the summer of 2003. These surveys extend the series of surveys, previously conducted every 3 years between 1984 and 1999, which constitute the time series used in stock assessments of Gulf of Alaska groundfish resources. The survey area covered the continental shelf and upper continental slope to 700 m in the Gulf of Alaska from Islands of Four Mountains (170° W long.) and continued eastward approximately 2,800 km across the Gulf of Alaska to Dixon Entrance (133° 25' W long.). The survey was conducted aboard three chartered commercial trawlers, the FV Gladiator, the FV Northwest Explorer and the FV Sea Storm. Trawl haul samples were collected successfully at 809 survey stations using standard RACE Division Poly Nor'Eastern high-opening bottom trawl nets with rubber bobbin roller gear. The primary survey objectives were to define the distribution and estimate the relative abundance of the principal groundfish within the survey area and to collect data to estimate biological parameters useful to groundfish researchers and managers including age; growth; length-weight relationships; feeding habits; and size, sex, and age composition. The survey also collected ancillary data requested by other research groups. More than 176 fish and 362 invertebrate species were captured in survey tows. The species highest in total catch abundance (by weight) over the entire survey area were arrowtooth flounder (Atheresthes stomias), Pacific halibut (Hippoglossus stenolepis), Pacific ocean perch (Sebastes alutus), and walleye pollock (Theragra chalcogramma). Survey results are presented including estimates of catch per unit of effort, biomass, population size composition, and lengthweight relationships, as well as charts depicting the distribution of catch for commercially important species encountered during the survey.