cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
PELMED 2021 cruise,L'Europe R/V
Creators: name: BOURDEIX Jean-Hervé
Publisher: name: Sismer
Year: 2021

description: La campagne PELMED est une campagne de prospection acoustique et de chalutages d'identification des espèces dans le Golfe du Lion avec une extension vers la région PACA. La prospection s'effectue selon des radiales parallèles distantes de 12 miles nautiques et perpendiculaires à la côte (9 radiales dans le Golfe du Lion) sur le plateau continental (20-200m de profondeur). Le plan d'échantillonnage inclut également les inter-radiales (trajet entre deux radiales), ce qui permet de prospecter sur une sonde constante et donc d'affiner la couverture spatiale.Son but premier est l'évaluation spatio-temporelle des biomasses de petits pélagiques, en particulier celle de l'anchois et de la sardine. En Méditerranée nord-occidentale, la majorité des populations reproductrices d'anchois se situent sur le plateau continental du Golfe du Lion et en Catalogne nord au mois de juillet, d'où le choix de cette période pour la réalisation de la campagne. Par ailleurs, le mois de juillet permet également de réaliser une estimation du recrutement de la sardine (qui se reproduit en hiver). De plus, les indicateurs découlant de cette campagne (évaluation de biomasse) ainsi que la recherche reposent sur l'historique des campagnes PELMED et il est donc nécessaire par souci de continuité et de comparaison entre années de poursuivre les observations à la même période chaque année (mois de juillet).Elle s'attache également à accumuler le plus de données possible sur les différents compartiments de l'écosystème pélagique, allant des paramètres physiques (température, salinité) aux prédateurs supérieurs (mammifères marins, oiseaux), en passant par les différents niveaux trophiques inférieurs (phyto- et zooplancton, poissons petits pélagiques). Ainsi, après chaque chalutage ou à chaque bout de radiale une station hydrologique est réalisée avec la mesure de la température, de la salinité et de la fluorescence le long de la colonne d'eau grâce à une bathysonde, la collecte d'eau de mer pour analyse phytoplanctonique grâce à une bouteille Niskin et des traits verticaux de filet à zooplancton (WP2). Enfin, tout au long de la campagne, un observateur est embarqué pour identifier et dénombrer les oiseaux et mammifères marins.
title: CalDraCor plays
title: 64 XML-TEI-encoded plays by Pedro Calderón de la Barca
titleType: Subtitle
Creators: name: Kroll, Simon
Year: 2024
Subjects: Romanistik
Romance studies
ÖFOS 2012 -- GEISTESWISSENSCHAFTEN (6) -- Sprach- und Literaturwissenschaften (602) -- Sprach- und Literaturwissenschaften (6020) -- Romanistik (602042)
ÖFOS 2012 -- HUMANITIES (6) -- Linguistics and Literature (602) -- Linguistics and Literature (6020) -- Romance studies (602042)
Calderón de la Barca, Pedro
Calderon de la Barca, P.
Calderón, Pedro
Calderón de la Barca, Peter
La Barka, Kalderons de
De la Barca, Pedro, Don
De la Barca, Pedro Calderón
Kalʹderon de la Barka, Pedro
Barca, Calderón de la
Don Pedro Calderon de la Barca
Kal'deron
Calderon, Pedro de la Barca
Calderon de la Barka, Pedro
La Barca, Don Pedro Calderón de
Calderón de la Barka
Calderón DeLaBarca, Pedro
Calderon, Pietro
La Barca, Pedro Calderón de
LaBarca, Pedro C. de
Calderón de la Barca
Calderón de la Barca, Pedro, Don
Calderon, Pedro
LaBarca, Pedro Calderón de
Calderon
Caldéron de la Barca, Pedro
Kalderon
Kalderons de la Barka
Barca, Pedro Calderón de la
Calderón
Calderón de la Parcae
La Barca, Pedro de, Don
Auto sacramental
Fronleichnamsspiel
Egloga sacramental
Siglo de oro
Spanisch / Literatur / Siglo de oro
Goldenes Zeitalter
17.97 Texte eines einzelnen Autors
Geisteswissenschaften -- Sprach- und Literaturwissenschaft: Allgemeines -- Literaturwissenschaft: Allgemeines -- Texte eines einzelnen Autors
17.98 Textsammlungen
Geisteswissenschaften -- Sprach- und Literaturwissenschaft: Allgemeines -- Literaturwissenschaft: Allgemeines -- Textsammlungen
Siglo de Oro
Teatro

description: 64 XML-TEI-encoded plays by Pedro Calderón de la Barca
PELMED 2022 cruise,L'Europe R/V
Creators: name: BOURDEIX Jean-Hervé
Publisher: name: Sismer
Year: 2022

description: La campagne PELMED est une campagne de prospection acoustique et de chalutages d'identification des espèces dans le Golfe du Lion avec une extension vers la région PACA. La prospection s'effectue selon des radiales parallèles distantes de 12 miles nautiques et perpendiculaires à la côte (9 radiales dans le Golfe du Lion) sur le plateau continental (20-200m de profondeur). Le plan d'échantillonnage inclut également les inter-radiales (trajet entre deux radiales), ce qui permet de prospecter sur une sonde constante et donc d'affiner la couverture spatiale.Son but premier est l'évaluation spatio-temporelle des biomasses de petits pélagiques, en particulier celle de l'anchois et de la sardine. En Méditerranée nord-occidentale, la majorité des populations reproductrices d'anchois se situent sur le plateau continental du Golfe du Lion et en Catalogne nord au mois de juillet, d'où le choix de cette période pour la réalisation de la campagne. Par ailleurs, le mois de juillet permet également de réaliser une estimation du recrutement de la sardine (qui se reproduit en hiver). De plus, les indicateurs découlant de cette campagne (évaluation de biomasse) ainsi que la recherche reposent sur l'historique des campagnes PELMED et il est donc nécessaire par souci de continuité et de comparaison entre années de poursuivre les observations à la même période chaque année (mois de juillet).Elle s'attache également à accumuler le plus de données possible sur les différents compartiments de l'écosystème pélagique, allant des paramètres physiques (température, salinité) aux prédateurs supérieurs (mammifères marins, oiseaux), en passant par les différents niveaux trophiques inférieurs (phyto- et zooplancton, poissons petits pélagiques). Ainsi, après chaque chalutage ou à chaque bout de radiale, une station hydrologique est réalisée avec la mesure de la température, de la salinité et de la fluorescence le long de la colonne d'eau grâce à une bathysonde, la collecte d'eau de mer pour analyse phytoplanctonique grâce à une bouteille Niskin et des traits verticaux de filet à zooplancton (WP2). Enfin, tout au long de la campagne, un observateur est embarqué pour identifier et dénombrer les oiseaux et mammifères marins.
PELMED 2023 cruise,L'Europe R/V
Creators: name: BOURDEIX Jean-Hervé
Publisher: name: Sismer
Year: 2023

description: La campagne PELMED est une campagne de prospection acoustique et de chalutages d'identification des espèces dans le Golfe du Lion avec une extension vers la région PACA. La prospection s'effectue selon des radiales parallèles distantes de 12 miles nautiques et perpendiculaires à la côte (9 radiales dans le Golfe du Lion) sur le plateau continental (20-200m de profondeur). Le plan d'échantillonnage inclut également les inter-radiales (trajet entre deux radiales), ce qui permet de prospecter sur une sonde constante et donc d'affiner la couverture spatiale.Son but premier est l'évaluation spatio-temporelle des biomasses de petits pélagiques, en particulier celle de l'anchois et de la sardine. En Méditerranée nord-occidentale, la majorité des populations reproductrices d'anchois se situent sur le plateau continental du Golfe du Lion et en Catalogne nord au mois de juillet, d'où le choix de cette période pour la réalisation de la campagne. Par ailleurs, le mois de juillet permet également de réaliser une estimation du recrutement de la sardine (qui se reproduit en hiver). De plus, les indicateurs découlant de cette campagne (évaluation de biomasse) ainsi que la recherche reposent sur l'historique des campagnes PELMED et il est donc nécessaire par souci de continuité et de comparaison entre années de poursuivre les observations à la même période chaque année (mois de juillet).Elle s'attache également à accumuler le plus de données possible sur les différents compartiments de l'écosystème pélagique, allant des paramètres physiques (température, salinité) aux prédateurs supérieurs (mammifères marins, oiseaux), en passant par les différents niveaux trophiques inférieurs (phyto- et zooplancton, poissons petits pélagiques). Ainsi, après chaque chalutage ou à chaque bout de radiale une station hydrologique est réalisée avec la mesure de la température, de la salinité et de la fluorescence le long de la colonne d'eau grâce à une bathysonde, la collecte d'eau de mer pour analyse phytoplanctonique grâce à une bouteille Niskin et des traits verticaux de filet à zooplancton (WP2). Enfin, tout au long de la campagne, un observateur est embarqué pour identifier et dénombrer les oiseaux et mammifères marins.
In silico assessment of a natural small molecule as an inhibitor of programmed death ligand 1 for cancer immunotherapy: a computational approach
Creators: name: Alharthi, Nahed S.
name: Alwethaynani, Maher S.
name: Alhazmi, Abdulfattah Y.
name: Alawam, Abdullah S.
name: Alshehri, Faez Falah
name: Alotaibi, Faisal
name: Rehman, Zia ur
name: Alkhayl, Faris F. Aba
name: Al-Bazi, Maha M.
name: Khan, Farhan R.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Programmed cell death ligand 1 (PD-L1) is a crucial target for cancer therapy. Here, an in silico study investigates PD-L1 to inhibit its interaction with PD1, thereby promoting an immune response to eliminate cancer cells. The study employed machine learning (ML) -based QSAR to detect PDL1 inhibitors. Morgan’s fingerprint with docking score showed a 0.83 correlation with the experimental IC50, enabling the screening of 3200 natural compounds. The top three compounds, considered 2819, 2821 and 3188, were selected from the ML-based QSAR and subjected to molecular docking and simulation. The binding scores for 2819, 2821 and 3188 were −7.0, −9.0 and −8.9 kcal/mol, respectively. The stability of the ligands during a 100 ns simulation was assessed using RMSD, showing that 2819 and 2821 maintained stable patterns comparable to the control inhibitor. Notably, 2819 exhibited a consistent stable pattern throughout the simulation, while 2821 showed stability in the last 40 ns. The control compound showed the highest number of hydrogen bonds with proteins, whereas compounds 2819 and 2821 formed continuous H-bonds. 3188 was separated from the protein in later phases and is not regarded as a potential PD-L1-binding molecule. MMGBSA binding free energy for complexes was computed. Control had the lowest binding free energy, while 2819 and 2821 also had lower binding energies. In contrast, 3188 showed poor binding free energy, causing protein separation. Principal component analysis showed a loss of entropy and reduced protein conformational variation. Overall, 2819 and 2821 are potential binders for PD-L1 inhibition and immune response triggering.
Sample size dependence of tagged molecule dynamics in steady-state networks with bimolecular reactions: Cycle times of a light-driven pump
Creators: name: Asnicar, Daniele
name: Penocchio, Emanuele
name: Frezzato, Diego
Publisher: name: arXiv
Year: 2022
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Here, steady-state reaction networks are inspected from the viewpoint of individual tagged molecules jumping among their chemical states upon the occurrence of reactive events. Such an agent-based viewpoint is useful for selectively characterizing the behavior of functional molecules, especially in the presence of bimolecular processes. We present the tools for simulating the jump dynamics both in the macroscopic limit and in the small-volume sample where the numbers of reactive molecules are of the order of few units with an inherently stochastic kinetics. The focus is on how an ideal spatial "compartmentalization" may affect the dynamical features of the tagged molecule. Our general approach is applied to a synthetic light-driven supramolecular pump composed of ring-like and axle-like molecules that dynamically assemble and disassemble, originating an average ring-through-axle directed motion under constant irradiation. In such an example, the dynamical feature of interest is the completion time of direct/inverse cycles of tagged rings and axles. We find a surprisingly strong robustness of the average cycle times with respect to the system's size. This is explained in the presence of rate-determining unimolecular processes, which may, therefore, play a crucial role in stabilizing the behavior of small chemical systems against strong fluctuations in the number of molecules.
description: 13 pages, 5 figures, 2 tables
PELMED 2024 cruise,L'Europe R/V
Creators: name: BOURDEIX Jean-Hervé
Publisher: name: Sismer
Year: 2024

description: La campagne PELMED est une campagne de prospection acoustique et de chalutages d'identification des espèces dans le Golfe du Lion avec une extension vers la région PACA. La prospection s'effectue selon des radiales parallèles distantes de 12 miles nautiques et perpendiculaires à la côte (9 radiales dans le Golfe du Lion) sur le plateau continental (20-200m de profondeur). Le plan d'échantillonnage inclut également les inter-radiales (trajet entre deux radiales), ce qui permet de prospecter sur une sonde constante et donc d'affiner la couverture spatiale.Son but premier est l'évaluation spatio-temporelle des biomasses de petits pélagiques, en particulier celle de l'anchois et de la sardine. En Méditerranée nord-occidentale, la majorité des populations reproductrices d'anchois se situent sur le plateau continental du Golfe du Lion et en Catalogne nord au mois de juillet, d'où le choix de cette période pour la réalisation de la campagne. Par ailleurs, le mois de juillet permet également de réaliser une estimation du recrutement de la sardine (qui se reproduit en hiver). De plus, les indicateurs découlant de cette campagne (évaluation de biomasse) ainsi que la recherche reposent sur l'historique des campagnes PELMED et il est donc nécessaire par souci de continuité et de comparaison entre années de poursuivre les observations à la même période chaque année (mois de juillet).Elle s'attache également à accumuler le plus de données possible sur les différents compartiments de l'écosystème pélagique, allant des paramètres physiques (température, salinité) aux prédateurs supérieurs (mammifères marins, oiseaux), en passant par les différents niveaux trophiques inférieurs (phyto- et zooplancton, poissons petits pélagiques). Ainsi, après chaque chalutage ou à chaque bout de radiale une station hydrologique est réalisée avec la mesure de la température, de la salinité et de la fluorescence le long de la colonne d'eau grâce à une bathysonde, la collecte d'eau de mer pour analyse phytoplanctonique grâce à une bouteille Niskin et des traits verticaux de filet à zooplancton (WP2). Enfin, tout au long de la campagne, un observateur est embarqué pour identifier et dénombrer les oiseaux et mammifères marins.
PELMED 85 cruise,Thalassa R/V
Creators: name: LIORZOU Bernard
name: MARCHAL Emile
Publisher: name: Sismer
Year: 1985

description: Etude de la macro distribution et de l'importance des principales ressources pélagiques dans le Golfe du Lion depuis les fonds de 20 mètres aux accores du plateau (150 mètres environ). Acquisition de données (index de réflexion des poissons, identification, comportement des bancs en relation avec les conditions de milieu, évitement par rapport au navire) permettant d'améliorer la méthodologie en matière d'évaluation des stocks par les procédés acoustiques.
Haplotype analysis, regulatory elements and docking simulation of structural models of different AT3 copies in the genus Capsicum
Creators: name: Burgos-Valencia, Eduardo
name: Echevarría-Machado, Ileana
name: Ortega-Lule, Gustavo
name: Medina-Lara, Fátima
name: García-Laynes, Federico
name: Martínez-Estévez, Manuel
name: Narváez-Zapata, José
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: Capsaicinoids are responsible for the pungency in Capsicum species. These are synthesized by the Capsaicin synthase (CS) encoded by the AT3 gene, which catalyzes the transference of an acyl moiety from a branched-chain fatty acid-CoA ester to the vanillylamine to produce capsaicinoids. Some AT3 gene copies have been identified on the Capsicum genome. The absence of capsaicinoid in some nonpungent accessions is related to mutant AT3 alleles. The differences between CS protein copies can affect the tridimensional structure of the protein and the affinity for its substrates, and this could affect fruit pungency. This study characterized 32 AT3 sequences covering Capsicum pungent and non-pungent accessions. These were clustered in AT3-D1 and AT3-D2 groups and representative sequences were analyzed. Genomic upstream analysis shows different regulatory elements, mainly responsive to light and abiotic stress. AT3-D1 and AT3-D2 gene expression was confirmed in fruit tissues of C. annuum. Amino acid substitutions close to the predictable HXXXD and DFGWG motifs were also identified. AT3 sequences were modeled showing a BAHD acyltransferase structure with two connected domains. A pocket with different shape, size and composition between AT3 models was found inside the protein, with the conserved motif HXXXD exposed to it, and a channel for their accessibility. CS substrates exhibit high interaction energies with the His and Asp conserved residues. AT3 models have different interaction affinities with the (E)-8-methylnon-6-enoyl-CoA, 8-methylnonanoyl-CoA and vanillylamine substrates. These results suggested that AT3-D1 and AT3-D2 sequences encode CS enzymes with different regulatory factors and substratum affinities.
PELMED 93 cruise,Thalassa R/V
Creators: name: LIORZOU Bernard
Publisher: name: Sismer
Year: 1993

description: Evaluation des stocks d'anchois du Golfe de Valence (ESPAGNE) au sud de la mer Ligure (ITALIE) et comparaison avec la méthode d'évaluation (Production journalière d'oeufs BFM = Batch Fecondity Method) mettant en jeu le Garcia del Cid (ESPAGNE) sur les mêmes secteurs et à la même période.
Thermonuclear reaction rate of $^{29}$Si(p,$γ$)$^{30}$P
Creators: name: Downen, Lori
name: Iliadis, Christian
name: Champagne, Art
name: Clegg, Thomas
name: Coc, Alain
name: Dermigny, Jack
Publisher: name: arXiv
Year: 2022
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The thermonuclear rate of the $^{29}$Si(p,$γ$)$^{30}$P reaction impacts the $^{29}$Si abundance in classical novae. A reliable reaction rate is essential for testing the nova paternity of presolar stardust grains. At present, the fact that no classical nova grains have been unambiguously identified in primitive meteorites among thousands of grains studied is puzzling, considering that classical novae are expected to be prolific producers of dust grains. We investigated the $^{29}$Si $+$ $p$ reaction at center-of-mass energies of $200$ $-$ $420$~keV, and present improved values for resonance energies, level excitation energies, resonance strengths, and branching ratios. One new resonance was found at a center-of-mass energy of $303$ keV. For an expected resonance at $215$~keV, an experimental upper limit could be determined for the strength. We evaluated the level structure near the proton threshold, and present new reaction rates based on all the available experimental information. Our new reaction rates have much reduced uncertainties compared to previous results at temperatures of $T$ $\ge$ $140$~MK, which are most important for classical nova nucleosynthesis. Future experiments to improve the reaction rates at lower temperatures are discussed.
description: 5 figures
The role of suffering in Jürgen Moltmann’s Theology of Hope
Creators: name: McIntyre, Lawrence
Publisher: name: St. Mark's College
Year: 2010

description: When Jürgen Moltmann wrote his first book, Theology of Hope, in the 1960s, hope was in the air. The 1960s was a decade of great hope. It was a time of great hope for the Catholic Church, with Vatican II. Hope was in the air for oppressed people, with the civil rights movement and the women’s liberation movement. And it was a time of great explorations that launched people into space and left footprints on the moon. Moltmann’s book resonated with the times. Its publication vaulted him from an obscure professor to the forefront of theology. The book shook up established principles of theology, including the meaning of eschatology -- that it wasn’t just about the end times or last things, but that it was about now. Yet, this time of great hope occurred just a few short years after a period of great suffering and despair -- World War II -- when millions lost their lives in battle or as innocent, collateral victims of war, or in the targeted murder of Jews that was the Holocaust. My claim that it is not a coincidence that hope follows suffering. Indeed, my claim is that hope emerges from suffering. This is true for the development of Moltmann’s theology of hope, i.e., it emerged from the suffering he experienced as a youth in Hitler’s military in WWII. And, more importantly, this is true for Christian hope. God has consistently responded to the suffering human condition with hope.
PELMED 95 cruise,L'Europe R/V
Creators: name: GUENNEGAN Yvon
Publisher: name: Sismer
Year: 1995

description: Evaluation des stocks de petits pélagiques et en particulier de l'anchois du Golfe du Lion, par la méthode directe. Elle utilise la technique de l'échointégration au cours des prospections de jour (enregistrement en continu du signal) et permet une évaluation spatio-temporelle de la biomasse des petits pélagiques sur les détections observées. Des chalutages d'identification sont réalisés, ainsi que des stations planctonologiques et hydrologiques permettant de caractériser le milieu. Le projet de rattachement est "Biologie et dynamique des espèces exploitées".
IMPROVING THE TEACHING OF THE TOPIC OF STYRENES USING INTERACTIVE METHODS.
Creators: name: Qudratov, Javohir
Publisher: name: Zenodo
Year: 2025

description: This study aims to improve the topic of chemistry "Styrenes" through interactive teaching methods. When the chemical properties of styrenes and the polymerization process are explained to students in the traditional way, their level of mastery of the subject may be low. Therefore, it is proposed to organize the educational process using the methods of "Brainstorming", "Role Playing", "Project Learning" and "Work in Small Groups". The results of the study confirmed the effectiveness of interactive methods and showed the importance of their widespread use in the educational process.
PELMED 96 cruise,L'Europe R/V
Creators: name: GUENNEGAN Yvon
Publisher: name: Sismer
Year: 1996

description: Evaluation des stocks de petits pélagiques et en particulier de l'anchois du golfe du Lion, par la méthode directe. Elle utilise la technique de l'échointégration au cours des prospections de jour (enregistrement en continu du signal) et permet une évaluation spatio-temporelle de la biomasse des petits pélagiques sur les détections observées. Des chalutages d'identification sont réalisés, ainsi que des stations planctonologiques et hydrologiques permettant de caractériser le milieu. Le projet de rattachement est "biologie et dynamique des espèces exploitées".
Supplementary document for Attention based neutral network for polarimetric image denoising - 5826295.pdf
Creators: name: Liu, Hedong
name: Zhang, Yizhu
name: Cheng, Zhenzhou
name: Zhai, Jingsheng
name: Hu, Haofeng
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Photonics and Electro-Optical Engineering (excl. Communications)

description: The denoising performance of our method on different materials and noise levels.
Myristoylated GRASP55 dimerizes in the presence of model membranes
Creators: name: Kava, Emanuel
name: Garbelotti, Carolina V.
name: Lopes, José Luiz S.
name: Costa-Filho, Antonio J.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biophysics
Biochemistry
Medicine
Cell Biology
Molecular Biology
Biological Sciences not elsewhere classified

description: The Golgi Reassembly and Stacking Proteins (GRASPs) are engaged in various functions within the cell, both in unconventional secretion mechanisms and structuring and organizing the Golgi apparatus. Understanding their specific role in each situation still requires more structural and functional data at the molecular level. GRASP55 is one of the GRASP members in mammals, anchored to the membrane via the myristoylation of a Gly residue at its N-terminus. Therefore, co-translational modifications, such as myristoylation, are fundamental when considering a strategy to obtain detailed information on the interactions between GRASP55 and membranes. Despite its functional relevance, the N-terminal myristoylation has been underappreciated in the studies reported to date, compromising the previously proposed models for GRASP-membrane interactions. Here, we investigated the synergy between the presence of the membrane and the formation of oligomeric structures of myristoylated GRASP55, using a series of biophysical techniques to perform the structural characterization of the lipidated GRASP55 and its interaction with biological lipid model membranes. Our data fulfill an unexplored gap: the adequate evaluation of the presence of lipidations and lipid membranes on the structure-function dyad of GRASPs.
On the size and local equations of fibres of general projections
Creators: name: Ran, Ziv
Publisher: name: arXiv
Year: 2022
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14n05, 14n15

description: For a general birational projection of a smooth nondegenerate projective $n$-fold from $\mathbb P^{n+c}$ to $\mathbb P^m$, $n
Molecular cloning, biophysical and in silico studies of Human papillomavirus 33 E2 DNA binding domain
Creators: name: Bharti
name: Nair, Maya S.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences

description: Human papillomavirus 33, a high-risk HPV strain, is mainly responsible for HPV infection and cervical cancer in Asian countries. The E2 protein of HPV 33 is a DNA-binding protein that plays a crucial role in viral replication and transcription. We have cloned, overexpressed, and purified the DNA binding domain of the E2 protein. Size exclusion chromatography results suggested that the protein exists in a homodimeric state in the native form. Circular dichroism data showed that the protein has a higher content of β-sheet. The melting temperature obtained from differential scanning calorimetry is 52.59 °C, and the protein is stable at pH 8 and is in a dimeric form at basic pH. The protein is monomeric or unfolded at a very low pH. Chemical denaturation studies suggested that the protein denatured and dissociated simultaneously. The DNA binding activity of the protein was also confirmed and it showed binding affinity in the order of 106 M−1. The protein structure was modeled using homology modeling and other bioinformatic tools. The virtual screening and molecular dynamic simulation studies were performed to find compounds that can act as potent inhibitors against E2 DBD. This study expands the understanding of the conserved structural and binding properties of HPV33 E2 DBD and provides the first report on the characterization of the viral protein.
PELMED 97 cruise,L'Europe R/V
Creators: name: GUENNEGAN Yvon
Publisher: name: Sismer
Year: 1997

description: Évaluation des ressources de petits pélagiques du Golfe du Lion par campagne écho-intégration et chalutages. Le projet de rattachement est "Évaluation des pêcheries ; sous projet 4 : R et P Méditerranée Petits Pélagiques".
D3.4.4 An audit report mapping the initial gender composition and distribution of research teams, for circulation to managers and decision- makers in the project.
Creators: name: British Nutrition Foundation
Publisher: name: Zenodo
Year: 2005
Subjects: NoE and NEXUS Projects
The EuroFIR Food Platform
EuroFIR

description: IntroductionUnder the Sixth Framework Programme (FP6), both Networks of Excellence and Integrated Projects are required to develop and implement a Gender Action Plan (GAP) aimed at promoting gender equality within their initiatives. Additionally, projects must report on the progress and outcomes of this plan.

A Gender Action Plan typically involves two key steps:

Analysis of the current situation – assessing the participation of women in research and identifying gender-related issues relevant to the specific research area.

Development of specific proposals – outlining practical measures to ensure balanced participation of men and women, promote gender equality throughout the project, and address the gender dimension of the research content.

During the first year of the EuroFIR project, one of the initial gender-focused activities was the collection and analysis of data on the gender composition and distribution within the consortium. This report presents a summary of that activity and its findings.
An Implementation of Stochastic Forces for the N-body code REBOUND
Creators: name: Rein, Hanno
name: Choksi, Nick
Publisher: name: arXiv
Year: 2022
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We describe the implementation of a new module which can be used to simulate physical systems in which the motion of particles is affected by stochastic forces. Such forces are expected to be present in turbulent circumstellar disks or remnant planetesimal disks. Our implementation offers a convenient way to generate correlated noise with a user-specified amplitude and auto-correlation time for each particle. The module has minimal memory requirements and is freely available within the REBOUNDx additional effects library.
description: 3 pages, 1 figure, accepted by RNAAS, source code available at https://github.com/dtamayo/reboundx
PELMED 98 cruise,L'Europe R/V
Creators: name: LIORZOU Bernard
Publisher: name: Sismer
Year: 1998

description: Évaluation directe de la ressource en petits pélagiques du golfe du Lion par écho-intégration. Le projet de rattachement est Biologie et dynamique des populations exploitées/Petits pélagiques de Méditerranée.
Synthesis, topology, molecular docking and dynamics studies of o-phenylenediamine derivative
Creators: name: Ganesan, T. Sankar
name: Elangovan, N.
name: Thirumavalavan, Munusamy
name: Seenan, Shanthi
name: Sowrirajan, S.
name: Chandrasekar, S.
name: Arumugam, Natarajan
name: Almansour, Abdulrahman I.
name: Mahalingam, Sakkarapalayam M.
name: M, Datta Darshan V
name: Kanchi, Subbarao
name: Sivaramakrishnan, Venketesh
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Physical Sciences not elsewhere classified
Medicine
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The N, N’-(1,2-phenylene) bis (1- (4- chlorophenyl) methanimine) (CS4) was synthesized and characterized by infrared (IR), absorption (UV-vis) and NMR (1H and 13C) spectral analyses. The structural parameters, vibrational frequencies, potential energy and the distribution analysis (PED) were calculated by using DFT with the basis set of B3LYP/cc-pVDZ and these spectral values were compared to the experimental values. HOMO and LUMO studied were performed in order to understand the stability and biological activity of the compound. The most reactive sites on the compound were investigated by utilizing MEP energy surface and Fukui function descriptor with the natural population analysis (NPA) of the charges. The study of the natural bond orbitals (NBO) reveals the delocalization of the intramolecular interaction of the charges in the compound. Additionally, topological investigations (ELF, LOL), determination of thermodynamic parameters and noncovalent interaction (NCI) study by using topology (RDG) analysis were also carried out. Finally, the molecular docking and molecular dynamics simulations was carried out by examining against glycosylphosphatidylinositol phospholipase D inhibitor receptor for distinct protein targets (3MZG).
PELMED 99 cruise,L'Europe R/V
Creators: name: BIGOT Jean-Louis
Publisher: name: Sismer
Year: 1999

description: Évaluation des ressources en petits pélagiques du golfe du Lion par echo-intégration et chalutages d'identification des échos observés. Le projet de rattachement est "Biologie et dynamique des populations exploitées/Pélagiques Méditerranée" (programme national de l'Ifremer).
Clumpy accretion in pre-main-sequence stars as a source of perturbations in circumstellar disks
Creators: name: Demidova, Tatiana V.
name: Grinin, Vladimir P.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences
subject: J.2.3
subject: 85-04

description: The development of perturbations in the circumstellar disks of pre-main-sequence stars caused by clumpy accretion was investigated. Here we perform 3D hydrodynamical smoothed particle hydrodynamics simulations of disks perturbed by a recent clump accretion event. These simulations are further explored by radiative transfer calculations to quantify the observational appearance of such disks. It was shown that the density waves in the disks were formed at the fall of the clump. After several revolutions they can transform into spirals and ring structures. Their images in millimeter wavelengths are very similar to those observed with Atacama Large Millimeter/submillimeter Array in some protoplanetary disks. We assume that clumpy accretion may be the source of such structures.
description: 14 pages, 18 figures, 1 table
Campo 65: storia, ricerca e valorizzazione di un contesto di archeologia del contemporaneo
Creators: name: Giuliano De Felice
name: Maria Turchiano
name: Sergio Chiaffarata Iannelli
name: Daniele Mittica
name: Giorgia Dato
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Cultural heritage
subject: contemporary archaeology
subject: Archaeology/methods
subject: Digital humanities
subject: mobile mapping
subject: Community participation

description: Il progetto "Scavare nel contemporaneo" affronta lo studio, la ricerca e la valorizzazione del Campo 65 di Altamura (BA), un sito archeologico contemporaneo caratterizzato da una ricca stratificazione storica. Originariamente campo di prigionia durante la Seconda Guerra Mondiale, il sito ha subito molteplici trasformazioni, divenendo campo di addestramento per partigiani jugoslavi, centro di raccolta per profughi rimpatriati e, successivamente, area destinata all'istruzione militare.

L'approccio interdisciplinare adottato integra archeologia, storia e antropologia, combinando analisi di documenti archivistici, fonti orali, scavi stratigrafici e tecnologie avanzate come il mobile mapping e la digitalizzazione 3D delle strutture. Questa metodologia consente una documentazione dettagliata e precisa del patrimonio, favorendo la sua conservazione e diffusione.

Parallelamente alla ricerca, il progetto coinvolge attivamente le comunità locali e internazionali tramite workshop di progettazione partecipata e la candidatura al programma "European Heritage Label". L'obiettivo finale è trasformare il Campo 65 in un luogo di memoria attiva, che stimoli riflessioni collettive su conflitti, pace e resilienza, garantendone al contempo una gestione sostenibile e una fruizione pubblica consapevole.
Anti-protozoal potential of electrospun polymeric nanofiber composite membranes for treatment of contaminated drinking water
Creators: name: Shalaby, Thanaa Ibrahim
name: Gaafar, Maha Reda
name: Mady, Rasha Fadly
name: Mogahed, Nermine Mogahed Fawzy Hussein
name: Issa, Yasmin Amr
name: Korayem, Sherifa Mohamed
name: Hezema, Nehal Nassef
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology

description: The effectiveness of conventional techniques for removal of water contaminants remains doubtful on micropollutants, including waterborne protozoa. To the best of knowledge, this study is the first highlighting the use of electrospun polymeric nanofiber composite membranes coated with metal nanoparticles against Cyclospora cayetanensis and Giardia lamblia in vitro. Plain and hybrid nanofiber membranes loaded with zinc oxide, copper oxide and silver nanoparticles were prepared, characterized, and used for filtration of contaminated drinking water. Comparison between membranes was achieved through water examination microscopically and molecularly, counting and viability assessment of trapped protozoa on the membranes after filtration. Moreover, the membranes were examined by scanning electron microscopy (SEM) for detection of the trapped Cyclospora oocysts and Giardia cysts ultrastructural changes. Results showed that following water filtration, no protozoa were detected microscopically and melting curves were not plotted. A statistically significant reduction in the number of viable Cyclospora oocysts and Giardia cysts incubated for 4 days was reported. By SEM, dramatic distortions were observed in the trapped protozoa on hybrid membranes with superiority of silver nanoparticles. We concluded that the electrospun polymeric nanofibers composite membranes can be considered a promising alternative to standard water filtration methods.
Optimized Partitioning and Priority Assignment of Real-Time Applications on Heterogeneous Platforms with Hardware Acceleration
Creators: name: Casini, Daniel
name: Pazzaglia, Paolo
name: Biondi, Alessandro
name: Di Natale, Marco
Publisher: name: arXiv
Year: 2022
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: Hardware accelerators, such as those based on GPUs and FPGAs, offer an excellent opportunity to efficiently parallelize functionalities. Recently, modern embedded platforms started being equipped with such accelerators, resulting in a compelling choice for emerging, highly computational intensive workloads, like those required by next-generation autonomous driving systems. Alongside the need for computational efficiency, such workloads are commonly characterized by real-time requirements, which need to be satisfied to guarantee the safe and correct behavior of the system. To this end, this paper proposes a holistic framework to help designers partition real-time applications on heterogeneous platforms with hardware accelerators. The proposed model is inspired by a realistic setup of an advanced driving assistance system presented in the WATERS 2019 Challenge by Bosch, further generalized to encompass a broader range of heterogeneous architectures. The resulting analysis is linearized and used to encode an optimization problem that jointly (i) guarantees timing constraints, (ii) finds a suitable task-to-core mapping, (iii) assigns a priority to each task, and (iv) selects which computations to accelerate, seeking for the most convenient trade-off between the smaller worst-case execution time provided by accelerators and synchronization and queuing delays.
PELMED2M cruise,L'Europe R/V
Creators: name: BIGOT Jean-Louis
Publisher: name: Sismer
Year: 2000

description: Evaluation des ressources en petits pélagiques du Golfe du Lion par écho-intégration et chalutages d'identification des échos observes. Le projet de rattachement est 'Biologie et dynamique des populations exploitées/Pélagiques Méditerranée' (programme national de l'Ifremer).
D3.4.3 Develop an information resource of the relevant national and European networks of women scientists
Creators: name: British Nutrition Foundation
Publisher: name: Zenodo
Year: 2005
Subjects: NoE and NEXUS Projects
The EuroFIR Food Platform
EuroFIR

description: Project SummaryEuroFIR, the world-leading European Network of Excellence on Food Composition Databank Systems (www.eurofir.net), is a collaborative partnership involving 40 universities, research institutes, and small-to-medium-sized enterprises (SMEs) across 21 countries.

The primary goal of EuroFIR is to develop, integrate, and maintain a comprehensive, coherent, and validated databank that serves as a single, authoritative source of food composition data for Europe.

The project is coordinated by Dr. Paul Finglas from the Institute of Food Research, UK.Contact: paul.finglas@bbsrc.ac.uk
Biochemical and in silico analysis of the binding mode of erastin with tubulin
Creators: name: Radha, Gudapureddy
name: Pragyandipta, Pratyush
name: Naik, Pradeep Kumar
name: Lopus, Manu
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology
subject: Cardiology

description: Erastin (ERN) is a small molecule that induces different forms of cell death. For example, it has been reported to induce ferroptosis by disrupting tubulin subunits that maintain the voltage-dependent anion channels (VDACs) of mitochondria. Although its possible binding to tubulin has been suggested, the fine details of the interaction between ERN and tubulin are poorly understood. Using a combination of biochemical, cell-model and in silico approaches, we elucidate the interactions of ERN with tubulin and their biological manifestations. After confirming ERN's antiproliferative efficacy (IC50, 20 ± 3.2 M) and induction of cell death in the breast cancer cell line MDA-MB-231, the binding interactions of ERN with tubulin were examined. ERN bound to tubulin in a concentration-dependent manner, disorganizing the structural integrity of the protein, as substantiated via the tryptophan-quenching assay and the aniline-naphthalene sulfonate binding assay, respectively. In silico studies based on molecular docking revealed a docking score of −5.863 kcal/mol, suggesting strong binding interactions of ERN with tubulin. Additionally, molecular dynamics simulation and Molecular Mechanics Poisson–Boltzmann Surface Area (MM-PBSA) analyses evinced the binding free energy (ΔGbinding) of −31.235 kcal/mol, substantiating strong binding affinity of ERN with tubulin. Ligplot analysis showed hydrogen bonding with specific amino acids (Asn A226, Thr A223, Gln B247 and Val B355). QikProp-based ADME (absorption, distribution, metabolism and excretion) assessment showed considerable therapeutic potential for ERN.
PENETRESS 2003 cruise,L'Atalante R/V
Creators: name: MEUNIER Jacques
Publisher: name: Sismer
Year: 2003

description: Campagne technologique d'essais de validation du nouveau gréement du pénétromètre Penfeld. Essais de fonctionnement du pénétromètre Penfeld par plus de 2000 m de profondeur.
Prototype Development and Validation of a Beam-Divergence Control System for Free-Space Laser Communications
Creators: name: Carrasco-Casado, Alberto
name: Shiratama, Koichi
name: Kolev, Dimitar
name: Trinh, Phuc V.
name: Fuse, Tetsuharu
name: Fuse, Shingo
name: Kawaguchi, Koji
name: Hashimoto, Yusuke
name: Hyodo, Masamitsu
name: Sakamoto, Takashi
name: Kunisada, Terufusa
name: Toyoshima, Morio
Publisher: name: arXiv
Year: 2022
Subjects: subject: Systems and Control (eess.SY)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Physical sciences

description: Being able to dynamically control the transmitted-beam divergence can bring important advantages in free-space optical communications. Specifically, this technique can help to optimize the overall communications performance when the optimum laser-beam divergence is not fixed or known. This is the case in most realistic space laser communication systems, since the optimum beam divergence depends on multiple factors that can vary with time, such as the link distance, or cannot be accurately known, such as the actual pointing accuracy. A dynamic beam-divergence control allows to optimize the link performance for every platform, scenario, and condition. NICT is currently working towards the development of a series of versatile lasercom terminals that can fit a variety of conditions, for which the adaptive element of the transmitted beam divergence is a key element. This manuscript presents a prototype of a beam-divergence control system designed and developed by NICT and Tamron to evaluate this technique and to be later integrated within the lasercom terminals. The basic design of the prototype is introduced as well as the first validation tests that demonstrate its performance.
description: 8 pages, 4 figures, 1 table
Multiple introductions and sustained local transmission of Monkeypox virus in Southern Brazil between 2022–2023
Creators: name: Godinho, Fernanda Marques
name: de Lima Bermann, Thales
name: de Oliveira, Mayara Mota
name: Barcellos, Regina Bones
name: Ruivo, Amanda Pellenz
name: de Melo, Viviane Horn
name: dos Santos, Franciellen Machado
name: Bauermann, Milena
name: Selayaran, Taina Machado
name: dos Santos Soares, Taina
name: Sesterheim, Patrícia
name: Baethgen, Ludmila Fiorenzano
name: Da Rocha, Fernanda Maria
name: Amaral, Karine Medeiros
name: Delela, Fernanda Crestina Leitenski
name: Mondini, Renata Petzhold
name: Vizeu, Sabrina
name: Gregianini, Tatiana Schäffer
name: da Veiga, Ana Beatriz Gorini
name: da Luz Wallau, Gabriel
name: Salvato, Richard Steiner
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Mpox is a zoonotic viral disease caused by the Monkeypox virus (MPXV). Human cases have been mainly restricted to the African continent until the worldwide multi-country outbreak unfolded in 2022. We reconstructed epidemiological links of 53 MPXV infections using genomic epidemiology in Rio Grande do Sul State, southern Brazil, during 2022 and 2023. We detected five well-supported clades, three representing local transmission chains that were mostly restricted to the 2022 virus spread, one supported year-long maintenance encompassing samples from 2022 and 2023, and one new importation from Europe in 2023. Our results provide new insights into the geographic extent of community transmission and its association with viral diversity during the more pronounced 2022 mpox upsurge and during the following lower incidence phase. These findings highlight the power of continued genomic surveillance to uncover hidden transmission chains to understand viral dynamics and inform public health responses. The detection of sustained transmission in the state is important to guide targeted control measures to curtail further community and international transmission and highlight the need for maintaining genomic surveillance efforts.