The Impact of Excluding Adverse Neonatal Outcomes on the Creation of Gestational Weight Gain Charts Among Women from Low- and Middle-income Countries with Normal and Overweight BMI
Creators: name: Tehrani, Fahimeh Ramezani
name: Unger, Holger W
name: Lachat, Carl
name: Maleta, Kenneth
name: Mohamed, Hamid Jan Jan
name: Hussein, Hawawu
name: Krebs, Nancy F
name: Rogerson, Stephen J
name: Roberfroid, Dominique
name: Rodrigues, Patricia Lima
name: Clayton, Peter Ellis
name: Mridha, Malay Kanti
name: Ramachandra, Preetha
name: Hambidge, K Michael
name: Hutcheon, Jennifer A
name: Dewey, Kathryn G
name: Cruickshank, John Kennedy
name: Sámano, Reyna
name: Bhutta, Zulfiqar
name: Cardoso, Marly Augusto
name: Mosquera, Paola Soledad
name: Ashorn, Ulla
name: Fawzi, Wafaie W
name: Lauer, Jacqueline M
name: Ayoola, Omolola Olukemi
name: Katz, Joanne
name: Ome-Kaius, Maria
name: Tielsch, James M
name: Gondwe, Austrida
name: Ghosh, Shibani
name: Muñoz-Manrique, Cinthya
name: Zhong, Chunrong
name: Khatry, Subarna K
name: Carrilho, Thais Rangel Bousquet
name: Fair, Frankie J
name: Melse-Boonstra, Alida
name: Mohamad, Marhazlina
name: Rivera, Juan
name: Soltani, Hora
name: de Araújo, Carla Adriane Leal
name: Martínez-Rojano, Hugo
name: Matias, Susana L
name: McClure, Elizabeth M
name: Loy, See Ling
name: Arifeen, Shams
name: Rondó, Patricia HC
name: Shrestha, Bhim P
name: Shrestha, Robin
name: Devakumar, Delanjathan
name: Collins, Shalean M
name: Prentice, Andrew M
name: Mangani, Charles
name: Chico-Barba, Gabriela
name: Adu-Afarwuah, Seth
name: Thomas, Tinku
name: Azizi, Fereidoun
name: Friis, Henrik
name: Berhane, Yemane
name: Soofi, Sajid
name: Kurpad, Anura V
name: Artes, Rinaldo
name: Iqbal, Romaina
name: Kulmala, Teija
name: Consortium, members of the GWG Pooling Project
name: Ashorn, Per
name: Kolsteren, Patrick
name: Dwarkanath, Pratibha
name: Yussif, Adam Bawa
name: Bernstein, Robin
name: dos Santos Vaz, Juliana
name: Martin-Prevel, Yves
name: Moore, Sophie
name: Martorell, Reynaldo
name: Lipoeto, Nur Indrawaty
name: López, Laura Beatriz
name: Huybregts, Lieven
name: Kumar, Pratap
name: Lartey, Anna
name: Wang, Dongqing
name: Calvo, Elvira Beatriz
name: Osrin, David
name: Natamba, Barnabas K
name: Rodríguez-Cano, Ameyalli
name: Malta, Maíra Barreto
name: Zeng, Lingxia
name: Yang, Nianhong
name: Accrombessi, Manfred
name: Wang, Molin
name: Saville, Naomi M
name: Shivalli, Siddharudha
name: Farias, Dayana Rodrigues
name: Estrada-Gutierrez, Guadalupe
name: Worku, Alemayehu
name: Costello, Anthony M
name: Briand, Valérie
name: Maiya, G Arun
name: da Silva Júnior, José Roberto
name: Behboudi-Gandevani, Samira
name: Cheng, Yue
name: Li, Qian
name: Assefa, Nega
name: Alves, João Guilherme
name: Bawah, Ahmed Tijani
name: Hallamaa, Lotta
name: Girard, Amy Webb
name: Zhu, Zhonghai
name: Gomo, Exnevia
name: Perichart-Perera, Otilia
name: Kac, Gilberto
name: Munim, Shama
name: Manandhar, Dharma S
name: Ramakrishnan, Usha
name: Miller, Joshua D
name: Young, Sera L
Publisher: name: Elsevier
Year: 2024

description: BACKGROUND: Existing gestational weight gain (GWG) charts vary considerably in their choice of exclusion/inclusion criteria, and it is unclear to what extent these criteria create differences in the charts' percentile values.
OBJECTIVES: We aimed to establish the impact of including/excluding pregnancies with adverse neonatal outcomes when constructing GWG charts.
METHODS: This is an individual participant data analysis from 31 studies from low- and middle-income countries. We created a dataset that included all participants and a dataset restricted to those with no adverse neonatal outcomes: preterm < 37 wk, small or large for gestational age, low birth weight < 2500 g, or macrosomia > 4000 g. Quantile regression models were used to create GWG curves from 9 to 40 wk, stratified by prepregnancy BMI, in each dataset.
RESULTS: The dataset without the exclusion criteria applied included 14,685 individuals with normal weight and 4831 with overweight. After removing adverse neonatal outcomes, 10,479 individuals with normal weight and 3466 individuals with overweight remained. GWG distributions at 13, 27, and 40 wk were virtually identical between the datasets with and without the exclusion criteria, except at 40 wk for normal weight and 27 wk for overweight. For the 10th and 90th percentiles, the differences between the estimated GWG were larger for overweight (∼1.5 kg) compared with normal weight (<1 kg). Removal of adverse neonatal outcomes had minimal impact on GWG trajectories of normal weight. For overweight, the percentiles estimated in the dataset without the criteria were slightly higher than those in the dataset with the criteria applied. Nevertheless, differences were <1 kg and virtually nonexistent at the end of pregnancy.
CONCLUSIONS: Removing pregnancies with adverse neonatal outcomes has little or no influence on the GWG trajectories of individuals with normal and overweight.