cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Multipair contributions to the spin response of nuclear matter
Creators: name: Olsson, E.
name: Pethick, C. J.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We analyse the effect of non-central forces on the magnetic susceptibility of degenerate Fermi systems. These include the presence of contributions from transitions to states containing more than one quasiparticle-quasihole pair, which cannot be calculated within the framework of Landau Fermi-liquid theory, and renormalization of the quasiparticle magnetic moment, as well as explicit non-central contributions to the quasiparticle interaction. Consequently, the relationship between the Landau parameters and the magnetic susceptibility for Fermi systems with non-central forces is considerably more complicated than for systems with central forces. We use sum-rule arguments to place a lower bound on the contribution to the static susceptibility coming from transitions to multipair states.
Stability of Big Surface Bubbles: Impact of Evaporation and Bubbles Size
Creators: name: Miguet, Jonas
name: Pasquet, Marina
name: Rouyer, Florence
name: Fang, Yuan
name: Rio, Emmanuelle
Publisher: name: arXiv
Year: 2019
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Surface bubbles have attracted much interest in the past decades. In this article, we propose to explore the lifetime and thinning dynamics of centimetric surface bubbles. We study the impact of the bubbles size as well as that of the atmospheric humidity through a careful control and systematic variation of the relative humidity in the measuring chamber. We first adress the question of the drainage under saturated water vapor conditions and show that a model including both capillary and gravity driven drainage provides the best prediction for this process. Additionally, unprecedented statistics on the bubbles lifetimes confirm experimentally that this parameter is set by evaporation to leading order. We make use of a model based on the overall thinning dynamics of the thin film and assume a rupture thickness of the order 10-100 nm to obtain a good representation of these data. For experiments conducted far from saturation, the convective evaporation of the bath is shown to dominate the overall mass loss in the cap film due to evaporation.
Surfaces of revolution in terms of solitons
Creators: name: Taimanov, I. A.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: The detailed analysis of the generalised Weierstrass representation of surfaces of revolution and their deformations induced by the modified Korteweg--de Vries (mKdV) equations is done. In particular, it is shown that these deformations preserve tori. The geometric meaning of the potential of surface is discussed and the deformations of potentials induced by geometric deformations (the Moebius inversion and a passing to a dual surface) are described. The conjecture of invariance of first integrals of the mKdV hierarchy, considering as invariants of surfaces, with respect to confomal changes of the metric of the ambient space is introduced. Some numeric computations confirming it are also presented. This paper is the sequel to the previous author's paper "Modified Novikov-Veselov equation and differential geometry of surfaces" (dg-ga/9511005) where generic surfaces are considered. Here the surfaces of revolution are regarded as a toy model for the general case.
description: 15 pages, LaTeX
title: Achtsamkeit und Meditation für Allgemeinmediziner*innen – sind Kommunikative Kompetenz, Empathiefähigkeit und Selbstfürsorge erlernbar?
Creators: name: Herrmann, Markus Ludwig
name: Vogelsänger, Peter
name: Brenne, Silke
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Kommunikative Kompetenz, Empathiefähigkeit und Selbstfürsorge gehören neben der Diagnosestellung und Behandlung von Krankheiten zu den wesentlichen Elementen professionellen ärztlichen Handelns. Sie sind vor dem Hintergrund einer zunehmenden Komplexität, Beschleunigung[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin
Pink's conjecture on unlikely intersections and families of semi-abelian varieties
Creators: name: Bertrand, Daniel
name: Edixhoven, Bas
Publisher: name: arXiv
Year: 2019
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14K05, 14G35, 11G15, 14K30, 11G15

description: The Poincaré torsor of a Shimura family of abelian varieties can be viewed both as a family of semi-abelian varieties and as a mixed Shimura variety. We show that the special subvarieties of the latter cannot all be described in terms of the group subschemes of the former. This provides a counter-example to the relative Manin-Mumford conjecture, but also some evidence in favour of Pink's conjecture on unlikely intersections in mixed Shimura varieties. The main part of the article concerns mixed Hodge structures and the uniformization of the Poincaré torsor, but other, more geometric, approaches are also discussed.
description: Final version, only minor edits. Latex source of published version available on journal's website
A binomial coefficient identity associated to a conjecture of Beukers
Creators: name: Ahlgren, Scott
name: Ekhad, Shalosh B.
name: Ono, Ken
name: Zeilberger, Doron
Publisher: name: arXiv
Year: 1998
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: A combinatorial identity that was needed in Ahlgren and Ono's proof of a certain congruence conjecture of Frits Beukers is stated, and a pointer to its WZ proof is given.
description: 1 page (AMSTeX)
DI (Differentiated Instruction) Does Matter! The Effects of DI on Secondary School Students’ Well-Being, Social Inclusion and Academic Self-Concept
Creators: name: Pozas, Marcela
name: Letzel, Verena
name: Lindner, Katharina-Theresa
name: Schwab, Susanne
Publisher: name: Humboldt-Universität zu Berlin
Year: 2021
Subjects: subject: inclusive education
subject: differentiated instruction (DI)
subject: students' perception
subject: school well-being
subject: social inclusion
subject: academic self-concept
subject: 370 Bildung und Erziehung

description: In consideration of the substantial increase in students’ learning demands, teachers are urged to address student heterogeneity in their daily teaching practice by means of differentiated instruction (DI). The practice of DI, as a vehicle to achieve inclusive education, not only aims to support all students’ academic learning but also foster their social and emotional development. However, current research in the field of DI has mostly been limited to an examination of its effects on students’ achievement outcomes. Consequently, the potential impact of DI on students’ socio-emotional outcomes has, till now, received very little attention. In order to address this gap in the research, the current researchers seek to investigate the effects of DI on school students’ well-being, social inclusion and academic self-concept. Survey participants in this study included 379 students from 23 inclusive and regular classes in secondary schools in Austria. Following multilevel analyses, the results have indicated that students’ rating of their teachers’ DI practice is positively associated with their school well-being, social inclusion and academic self-concept. However, a t-test for dependent samples demonstrated that students perceive their teachers’ DI practice to be infrequent. Implications of the results along with further lines of research are also presented in this paper.
Metallic Network of Topological Domain Walls
Creators: name: Hou, Tao
name: Ren, Yafei
name: Quan, Yujie
name: Jung, Jeil
name: Ren, Wei
name: Qiao, Zhenhua
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the electronic and transport properties of a network of domain walls between insulating domains with opposite valley Chern numbers. We find that the network is semi-metallic with Dirac dispersion near the charge neutrality point and the corresponding electronic states distribute along the domain walls. Near the charge neutrality point, we find quantized conductance in nanoribbon with sawtooth domain wall edges that propagates along the boundaries and is robust against weak disorder. For a trident edged ribbon, we find a small energy gap due to the finite size effect making the nanoribbon an insulator. When the Fermi energy is away from charge neutrality point, all domain walls contribute to the conduction of current. Our results provide a comprehensive analysis of the electronic transport properties in a topological domain wall network that not only agrees qualitatively with experiments on marginally twisted bilayer graphene under a perpendicular electric field, but also can provide useful insights for designing low-power topological quantum devices.
Additional file 1: of Unravelling the sex- and age-specific impact of poaching mortality with multievent modeling
Creators: name: Corlatti, Luca
name: Sanz-Aguilar, Ana
name: Tavecchia, Giacomo
name: Gugiatti, Alessandro
name: Pedrotti, Luca
Publisher: name: figshare
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Multievent model design. (PDF 205 kb)
Looking at the axionic dark sector with ANITA
Creators: name: Esteban, Ivan
name: Lopez-Pavon, Jacobo
name: Martinez-Soler, Ivan
name: Salvado, Jordi
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The ANITA experiment has recently observed two anomalous events emerging from well below the horizon. Even though they are consistent with tau cascades, a high energy Standard Model or Beyond the Standard Model explanation is challenging and in tension with other experiments. We study under which conditions the reflection of generic radio pulses can reproduce these signals. We propose that these pulses can be resonantly produced in the ionosphere via axion-photon conversion. This naturally explains the direction and polarization of the events and avoids other experimental bounds.
description: New figure added (Fig. 5): estimation of ALP mass, coupling and corrected value of burst density, consistent with ANITA and present ALP experimental bounds. Estimation of ALP burst rate reaching the Earth added. Matches version accepted by EPJC
Development of Trimethoprim Chemical Tags for Single Molecule Imaging in Live Cells
Creators: Wang, Tracy Yuh
Publisher: name: Columbia University
Year: 2015
Subjects: Chemistry
Biochemistry

description: By tagging biomolecules with bright and photostable fluorophores, chemical tags enable single molecule (SM) detection and imaging for the study of biological mechanism. One of these tags. the trimethoprim chemical tag (TMP-tag), labels biomolecules using the high affinity interaction between E.coli dihydrofolate reductase and fluorescent derivatives of the antibiotic trimethoprim. The TMP-tag is one of the few chemical tags that has enabled live cell SM imaging. In this work, I present the development of the TMP-tag as a versatile tool for SM imaging. First, I establish that the TMP-tag is a robust tool for labeling proteins with organic fluorophores that enable SM detection and imaging. I then examine the properties of novel organic fluorophores that expand the palette of dyes that can be used with SM imaging. I also investigate fluorescent nanodiamonds for expanded imaging and sensing capabilities in live cells using the TMP-tag. Finally, I explore applications of the TMP-tag to label and image ion channels for the identification of pharmacological chaperones as therapeutics for protein mistrafficking diseases. Together, these studies highlight the versatility of the TMP-tag, furthering our ability to study biomolecules under challenging imaging and biological conditions.
Symmetry classification and invariant solutions of the classical geometric mean reversion process
Creators: name: Zhang, Jin
name: Gao, Dapeng
Publisher: name: arXiv
Year: 2025
Subjects: subject: Dynamical Systems (math.DS)
subject: Analysis of PDEs (math.AP)
subject: Probability (math.PR)
subject: Mathematical Finance (q-fin.MF)
subject: FOS: Mathematics
subject: FOS: Economics and business

description: Based on the Lie symmetry method, we investigate a Feynman-Kac formula for the classical geometric mean reversion process, which effectively describing the dynamics of short-term interest rates. The Lie algebra of infinitesimal symmetries and the corresponding one-parameter symmetry groups of the equation are obtained. An optimal system of invariant solutions are constructed by a derived optimal system of one-dimensional subalgebras. Because of taking into account a supply response to price rises, this equation provides for a more realistic assumption than the geometric Brownian motion in many investment scenarios.
title: Vortrags-Didaktik
Creators: name: Dannenberg, Manja
name: Engel, Bettina
name: Karl, Ilja
name: Mainz, Armin
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Erfreulicherweise haben allgemeinmedizinische Forschungsergebnisse mittlerweile auch in Deutschland einen beachtlichen Umfang erreicht. Die daraus abzuleitenden Botschaften an die Anwender*Innen sollen die medizinische Versorgung verbessern. Es bedarf einiger didaktischer Kompetenzen,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin
title: Laser Cooling and Trapping of Metastable Neon and Applications to Photoionization
Creators: name: Ashmore, Jonathan P
Publisher: name: Griffith University
Year: 2005
Subjects: subject: Metastable neon
subject: laser cooling and trapping
subject: photoionization
subject: Zeeman slowed atomic beam
subject: magneto-optical trap
subject: Doppler theory

description: This thesis presents an in-depth study into the characterization and enhancement of a metastable neon laser cooled and trapped atomic beam. The apparatus consists of a standard Zeeman slowed atomic beam loaded into a magneto-optical trap and was designed for applications to electron scattering experiments and photoionization. The efficiency of the metastable neon atomic source was investigated to determine the ideal cathode type for maximum metastable production and optimal atomic beam velocity haracteristics. A series of characterization measurements were performed on the MOT, and the trap volume and population were investigated for a range of trapping and slowing laser intensities and detunings, together with the MOT and Zeeman slower magnetic fields. The volume measurements were compared to standard Doppler theory and it was found that the Doppler model inadequately explained the trap behaviour. It was found that the MOT population characteristics were governed by two processes: two-body losses that limit the trap population at high densities, and the efficiency of the atom capture process which limits the operational range of the MOT over the various parameters. The trap temperature was determined to be 1.3mK via a time-of-flight technique. This was nearly twice that predicted by Doppler theory and the lack of agreement once again suggests the inadequacies in the Doppler theory to correctly model the experiment. The application of the MOT to the photoionization cross-section measurement of the (2p53p)3D3 state of neon was investigated. The MOT decay technique was utilized to measure cross-section values of o351 = 2.9+0.2 -0.3 x 10 -18cm2 and o363 = 3.1 +0.3 -0.4 x 10-18cm2 at the wavelengths of 351nm and 363nm respectively. This is an increase in accuracy of around a factor of five from previous measurements and it was found that the results agreed well with the values predicted by current theories.
Microelectromechanical-System-Based Design of a High-Finesse Fiber Cavity Integrated with an Ion Trap
Creators: name: Lee, Moonjoo
name: Lee, Minjae
name: Hong, Seokjun
name: Schüppert, Klemens
name: Kwon, Yeong-Dae
name: Kim, Taehyun
name: Colombe, Yves
name: Northup, Tracy E.
name: Cho, Dong-Il "Dan"
name: Blatt, Rainer
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: Applied Physics (physics.app-ph)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We present a numerical study of a MEMS-based design of a fiber cavity integrated with an ion trap system. Each fiber mirror is supported by a microactuator that controls the mirror's position in three dimensions. The mechanical stability is investigated by a feasibility analysis showing that the actuator offers a stable support of the fiber. The actuators move the fibers' positions continuously with a stroke of more than 10 $μ$m, with mechanical resonance frequencies on the order of kHz. A calculation of the trapping potential shows that a separation between ion and fiber consistent with strong ion-cavity coupling is feasible. Our miniaturized ion-photon interface constitutes a viable approach to integrated hardware for quantum information.
description: 14 pages, 11 figures, 3 tables
Additional file 8: of Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation
Creators: name: Costa, Elodie Da
name: Armaos, Gregory
name: McInnes, Gabrielle
name: Beaudry, Annie
name: Moquin-Beaudry, Gaël
name: Bertrand-Lehouillier, Virginie
name: Caron, Maxime
name: Richer, Chantal
name: St-Onge, Pascal
name: Johnson, Jeffrey
name: Nevan Krogan
name: Sai, Yuka
name: Downey, Michael
name: Moutih Rafei
name: Boileau, Meaghan
name: Eppert, Kolja
name: Flores-Díaz, Ema
name: Haman, André
name: Hoang, Trang
name: Sinnett, Daniel
name: Beauséjour, Christian
name: McGraw, Serge
name: Raynal, Noël
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Computational Biology

description: Figure S7. Loss of Acetylation In MYC Protein And MYC After Proscillaridin A Treatment In High MYC Expressing Cells. A Mass spectrometry analysis on 2 MYC peptides (LVSEK(ac)LASYQAAR) after proscillaridin A treatment (5nM; 48h) in MOLT-4. Log2 normalized intensity is shown (* indicates P<0.001; paired t-test; n=4). B Map of co-expression pathways of the 28 proteins that lost acetylation after proscillaridin A treatment (5 nM; 48h) in MOLT-4 cells. (PDF 890 kb)
title: Kommunikation für eine gelingende Kooperation in Beratung und Therapie
Creators: name: Petzold, Theodor Dierk
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die Beziehung zwischen Arzt/Therapeut und Patient wird als Kooperation gesehen. Wenn Beziehung ein wichtiger Heilfaktor sein soll, so können wir diesen differenzierter bestimmen, wenn wir diese als Zusammenwirken, als Kooperation verstehen. Wie kann diese Kooperation gelingen?[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin
Relating Profile Wall Root-Length Density Estimates to Monolith Root-Length Density Measurements of Cover Crops
Creators: name: Bublitz, Tabata Aline
name: Kemper, Roman
name: Müller, Phillip
name: Kautz, Timo
name: Döring, Thomas
name: Athmann, Miriam
Publisher: name: Humboldt-Universität zu Berlin
Year: 2021
Subjects: subject: catch crops
subject: cumulative root-length
subject: root distribution
subject: calibration
subject: regression analysis
subject: 630 Landwirtschaft und verwandte Bereiche

description: Different methods have been proposed for in situ root-length density (RLD) measurement. One widely employed is the time-consuming sampling of soil cores or monoliths (MO). The profile wall (PW) method is a less precise, but faster and less laborious alternative. However, depth-differentiated functions to convert PW RLD estimates to MO RLD measurements have not yet been reported. In this study, we perform a regression analysis to relate PW results to MO results and determine whether calibration is possible for distinct crop groups (grasses, brassicas and legumes) consisting of pure and mixed stands, and whether soil depth affects this calibration. The methods were applied over two years to all crop groups and their absolute and cumulative RLD were compared using a linear (LR) and multiple linear (MLR) regression. PW RLD was found to highly underestimate MO RLD in absolute values and in highly rooted areas. However, a close agreement between both methods was found for cumulative root-length (RL) when applying MLR, highlighting the influence of soil depth. The level of agreement between methods varied strongly with depth. Therefore, the application of PW as the main RLD estimation method can provide reliable estimates of cumulative root distribution traits of cover crops.
title: Treffen der AG-Impfen – Quartäre Prävention beim Impfen
Creators: name: Schneider-Rathert, Wolfgang
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Jahrestreffen der AG Impfen, Bericht der Ergebnisse des Europaprojekts, Beratung über das weitere Vorgehen zu den Sicherheitsdaten für Infanrix Hexa, Plan für 2019/2020 Zielgruppe: Mitglieder der AG Impfen Didaktische Methode: Workshop, Kurzvorträge, Kleingruppenarbeit[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin
How Much Should a 19th-Century French Bastard Inherit
Creators: name: Zeilberger, Doron
Publisher: name: arXiv
Year: 1998
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: Catalan's formula, for the portion of the inheritance that a legitimate child of a 19th-century deceased French gentleman should receive, is given a new proof (using Difference Operators), and generalized. Another, more computationally efficient, formula is also derived.
description: Plain TeX
title: Procedural Films: Algorithmic Affect in Research Media Art Practice
Creators: name: Anikina, Alexandra
Publisher: name: Goldsmiths, University of London
Year: 2020

description: This thesis explores the political aesthetics of ‘procedural films’—media works that use generative algorithmic procedures and manifest as moving images. In contrast to long-held techno-positivist understandings of generative art, the thesis reframes procedural films as a critical media art practice aiming to understand the ‘procedure’ as an affective engine of moving image experience. It employs an interdisciplinary approach that borrows from materialist theories of media, experimental film, artificial life and computational culture, and draws on my practices as artist and curator. These processes of making, curating and experiencing serve as enacted research, as a scalable architecture of thinking through and thinking with the technical media. The thesis proposes a conceptual framework for exploring procedural films as techno-cultural artefacts, addressing the ‘apparatus’, the affective space-time of their viewing and their sociopolitical operation. It proposes that algorithmic autonomy brings an affective renegotiation of the traditional roles of the spectator and the moving image, instead seeing it as a complex entanglement of human and non-human agencies, computational temporalities and generative procedures. Furthermore, it addresses procedural mediation and automation as a part of the political aesthetics of media art, exploring the techno-capitalist commodification of attention, time and images. The thesis investigates two case studies—screensaver and game engine—as procedural apparatuses. It explores these media artefacts as sites of labour, design, affect and experience, addressing their techno-cultural construction, as well as their processes of liveness and emergence.
title: Akademische Allgemeinmedizin – Sichtbarmachung des Mittelbaus
Creators: name: Leve, Verena
name: Heim, Susanne
name: Hueber, Susann
name: Riemenschneider, Henna
name: Schlößler, Kathrin
name: Santos, Sara
name: Voigt, Karen
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Für die Sicherung der allgemeinmedizinischen Forschung und Lehre ist der wissenschaftliche Mittelbau von großer Bedeutung. Wissenschaftliche Mitarbeiter*innen zeichnen sich für die Durchführung von Forschungsprojekten verantwortlich und sind maßgeblich an der[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin
Boundary states with elevated critical temperatures in Bardeen-Cooper-Schrieffer superconductors
Creators: name: Samoilenka, Albert
name: Babaev, Egor
Publisher: name: arXiv
Year: 2019
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Bardeen-Cooper-Schrieffer (BCS) theory describes a superconducting transition as a single critical point where the gap function or, equivalently, the order parameter vanishes uniformly in the entire system. We demonstrate that in superconductors described by standard BCS models, the superconducting gap survives near the sample boundaries at higher temperatures than superconductivity in the bulk. Therefore, conventional superconductors have multiple critical points associated with separate phase transitions at the boundary and in the bulk. We show this by revising the Caroli-De Gennes-Matricon theory of a superconductor-vacuum boundary and finding inhomogeneous solutions of the BCS gap equation near the boundary, which asymptotically decay in the bulk. This is demonstrated for a BCS model of almost free fermions and for lattice fermions in a tight-binding approximation. The analytical results are confirmed by numerical solutions of the microscopic model. The existence of these boundary states can manifest itself as discrepancies between the critical temperatures observed in calorimetry and transport probes.
description: published version
Development of Vessels, Airways and Cartilage Rings: The role of T-box genes
Creators: Arora, Ripla
Publisher: name: Columbia University
Year: 2012
Subjects: subject: Developmental biology
subject: Genetics
subject: FOS: Biological sciences

description: Tbx4 and Tbx5 are two closely related genes that belong to the T-box family of transcription factor genes. Loss of Tbx4 results in absence of chorio-allantoic fusion and a failure of formation of the primary vascular plexus of the allantois leading to embryonic death at E10.5. Using a candidate gene approach we identified a number of genes downstream of Tbx4 in the allantois including, extracellular matrix molecules Vcan, Has2, Itgα5; transcription factors Snai1 and Twist, and signaling molecules Bmp2, Bmp7, Notch2, Jag1 and Wnt2In addition, we show that the canonical Wnt signaling pathway contributes to the vessel-forming potential of the allantois. Ex vivo, the Tbx4 mutant phenotype can be rescued using agonists of the Wnt signaling pathway and an inhibitor of the canonical Wnt signaling pathway phenocopies the Tbx4mutant phenotype in wildtype allantoises. In vivo, Tbx4 and Wnt2 double heterozygous placentas show decreased vasculature suggesting interactions between Tbx4 and the canonical Wnt signaling pathway in the process of allantois-derived blood vessel formation. Both Tbx4 and Tbx5 are expressed throughout the mesenchyme of the developing respiratory system. Normal development of the respiratory system is essential for survival and is regulated by multiple genes and signaling pathways. Although many genes are known to be required in the epithelium, only Fgfs have been well studied in the mesenchyme. We investigated the roles of Tbx4 and Tbx5 in lung and trachea development using conditional mutant alleles and two different Cre recombinase transgenic lines. Loss of Tbx5 leads to a unilateral loss of lung bud specification and absence of tracheal specification in organ culture. Mutants deficient in Tbx4 and Tbx5 show severely reduced lung branching at mid-gestation. Concordant with this defect, the expression of mesenchymal markers Wnt2 and Fgf10, as well as Fgf10 target genes in the epithelium, Bmp4 and Spry2, is downregulated. Lung branching undergoes arrest ex vivo when Tbx4 and Tbx5 are both completely lacking. Lung-specific Tbx4 heterozygous; Tbx5 conditional null mice die soon after birth due to respiratory distress. These pups have small lungs and show severe disruptions in tracheal-bronchial cartilage rings. Sox9 a master regulator of cartilage formation, is expressed in the trachea but mesenchymal cells fail to condense and consequently do not develop cartilage normally at birth. Tbx4;Tbx5 double heterozygous mutants show decreased lung branching and fewer tracheal cartilage rings, suggesting a genetic interaction. Finally, we show that Tbx4 and Tbx5 interact with Fgf10 during the process of lung growth and branching but not during tracheal bronchial cartilage development.
An upper bound on the time required to implement unitary operations
Creators: name: Lee, Juneseo
name: Arenz, Christian
name: Burgarth, Daniel
name: Rabitz, Herschel
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We derive an upper bound for the time needed to implement a generic unitary transformation in a $d$ dimensional quantum system using $d$ control fields. We show that given the ability to control the diagonal elements of the Hamiltonian, which allows for implementing any unitary transformation under the premise of controllability, the time $T$ needed is upper bounded by $T\leq \frac{πd^{2}(d-1)}{2g_{\text{min}}}$ where $g_{\text{min}}$ is the smallest coupling constant present in the system. We study the tightness of the bound by numerically investigating randomly generated systems, with specific focus on a system consisting of $d$ energy levels that interact in a tight-binding like manner.
On polynomial recurrence for reliability system with a warm reserve
Creators: name: Veretennikov, Alexander
Publisher: name: arXiv
Year: 2019
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60K15, 60K20

description: Conditions for positive and polynomial recurrence have been proposed for a class of reliability models of two elements with transitions from working state to failure and back. As a consequence, uniqueness of stationary distribution of the model is proved; the rate of convergence towards this distribution may be theoretically evaluated on the basis of the established recurrence.
description: 20 pages, 15 references; some errors corrected in comparison with the version v1
Najash APESTEGUIA AND ZAHER 2006
Creators: name: Zaher, Hussam
name: Apesteguía, Sebastián
name: Scanferla, Carlos Agustín
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Reptilia
Squamata
Madtsoiidae
Najash

description: NAJASH APESTEGUÍA AND ZAHER, 2006
 Emended diagnosis: A snake nearly 2 m long with robust hindlimbs and a sacrum, tip of dentaries with a medially projected facet that bears a straight anteroposteriorly directed margin, suggesting a tightly connected mandibular symphysis, lack of dentary shelf, prootic exposed dorsally between the otooccipital and parietal, lack of laterosphenoid, developed laterally projected basipterygoid process, lack of a crista circumfenestralis, robust stapedial footplate, single large parazygantral foramen on vertebrae, arqual ridges on middle and posterior presacral vertebrae, and blunt haemapohyses on caudal vertebrae. It exhibits the following autapomorphies: (1) a thick splenial; (2) strongly concave ventral surface of the parasphenoid rostrum, forming a deep and straight gutter; (3) strongly faceted condition of the neural arch laminae; (4) enlarged and blade-like femoral trochanter.
description: Published as part of Zaher, Hussam, Apesteguía, Sebastián & Scanferla, Carlos Agustín, 2009, The anatomy of the upper cretaceous snake Najash rionegrina Apesteguía & Zaher, 2006, and the evolution of limblessness in snakes, pp. 801-826 in Zoological Journal of the Linnean Society 156 on page 803
title: The National Art School - A Social History from 1833 to 1973 and a Catalogue of the Archival Art Collection
Creators: name: Turner, Noele
Publisher: name: Griffith University
Year: 2012
Subjects: subject: National Art School, Sydney
subject: Alexander Mackie College of Advanced Education

description: At the core of this thesis is a broad social history of the origin of the National Art School (NAS), dating from the earliest days of art history in NSW when the Mechanics Institute was formed. From 1833, after many incarnations and name changes, this organisation evolved into the National Art School. Since 1922 it has been located in the old Darlinghurst Gaol in East Sydney. I have detailed the growth of the School until 1973 when it was absorbed into the Alexander Mackie College of Advanced Education. The documentary material used in the construction of the NAS history is examined in relation to the social and political forces that operated in Sydney and Australia during the period under examination. The thesis began as a project to catalogue the extensive collection of student paintings held by the NAS. The lack of documentation, at the most basic level of student and staff names, extended the necessary scope of the research. The photographic record of the collection of student paintings is included as an appendix, as is the catalogue of these works. My thesis also includes, as appendices, the definitive (although incomplete) list of over 4,000 past student names, dating from the beginning of the twentieth century to 1973, and an incomplete, although comprehensive list of teachers names covering the same period. It has taken some years of research to compile these listings from a variety of official, published and press sources.
The Character of Transport Caused by ExB Drift Turbulence
Creators: name: Scott, Bruce D.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The basic character of diffusive transport in a magnetised plasma depends on what kind of transport is modelled. ExB turbulence under drift ordering has special characteristics: it is nearly incompressible, and it cannot lead to magnetic flux diffusion if it is electrostatic. The ExB velocity is also related to the Poynting energy flux. Under quasineutral dynamics, electric fields are not caused by transport of electric charge but by the requirement that the total current is divergence free. Consequences for well constructed computational transport models are discussed in the context of a general mean field analysis, which also yields several anomalous transfer mechanisms not normally considered by current models.
description: 31 pages including 2 figures, submitted to Physics of Plasmas
Common training programme for R&I officers
Creators: name: Silveira, Lina
name: Paramio, Luz
name: Nascimento, Gisela
Publisher: name: Zenodo
Year: 2021
Subjects: ORs
outermost regions
research
innovation
capacity building
research excellence

description: A common training programme for R&I officers of Outermost Regions (ORs) is provided in the deliverable. The programme sets a common basis for the training of ORs’ Officer teams to develop their expected services to support local R&I communities.
Allies for women leaders in STEMM: Thoughts from an 'unabashed optimist'
Creators: name: Hornberger, George M.
name: Maurice, Patricia A.
Publisher: name: Zenodo
Year: 2024

description: This is a copy of a blog posted on the Epistimi website at: https://www.epistimi.org/blog/allies-for-women-leaders-in-stemm-thoughts-from-an-unabashed-optimist
title: An Investigation of the Casualisation of Academic Work in Australia
Creators: name: May, Robyn Lee
Publisher: name: Griffith University
Year: 2014
Subjects: subject: Academic staffs, Australia
subject: Casualisation of academic work, Australia

description: Australia’s universities have undergone a transformation over the past three decades. These changes have impacted heavily on academic staff and academic work. For some the ‘ivory tower’ offering lifelong academic employment still exists, while many others aspire to it. However, the reality of working life for most academic staff in Australia’s universities is increasingly characterised by an institutional invisibility manifest in poor conditions, lack of career path and no job security. Much of the teaching work in Australia’s universities today is performed by casual, hourly paid, staff underscoring this bifurcation of academic work. Casualisation of academic work has arisen from a mix of demand side and supply side factors, overlayed by the regulatory environment and the impact of new forms of public management on the university sector. These processes are part of a re-shaping of academic work and they sit within what is currently a highly complex and challenging environment for universities. Universities operate in a competitive and volatile global context, and have their missions and purpose framed firmly by economic imperatives.
Development of a genetically encoded site-specific fluorescent sensor of human cardiac voltage-gated sodium channel inactivation
Creators: Shandell, Mia
Publisher: name: Columbia University
Year: 2018
Subjects: Pharmacology
Sodium channels
Molecular biology
Biosensors

description: Genetic mutations perturbing inactivation of human cardiac voltage-gated sodium channels (VGSCs), specifically Nav1.5, can cause long QT syndrome type 3 (LQT3). LQT3 is a cardiac disorder in which patients experience syncope and ventricular tachyarrhythmia, and are thus predisposed to sudden cardiac death. Deeper understanding of the structural dynamics of VGSC inactivation is needed to inform treatment of and drug design for potentially life-threatening arrhythmias. A well supported hypothesis is that the VGSC inactivated state is stabilized by hydrophobic interactions between the inactivation gate and an unknown binding site potentially involving the underside of the channel pore, C-terminus (C-T), and auxiliary proteins. Despite advances in biophysical and structural characterization of VGSCs, the specific molecular components and timing of their interactions within the inactivation complex remain unclear. Fluorescence imaging approaches that connect conformational change with channel function in mammalian cells could provide much needed mechanistic insight on the structural dynamics of the VGSC inactivation complex. This thesis describes the development of a site-specific fluorescent unnatural amino acid (UAA) labeling and spectral imaging methodology to probe the cardiac VGSC, Nav1.5, inactivation complex in live mammalian cells. First, UAA mutagenesis experiments were performed to validate orthogonal synthetase-tRNA (aaRS-tRNA) technology for fluorescent labeling of intracellular and membrane proteins in mammalian cells. Next, towards investigating conformational dynamics and intramolecular interactions related to inactivation, the Nav1.5 inactivation gate was labeled with a single environmentally sensitive fluorescent UAA L-anap. While the function of L-anap labeled channels was altered, their function remained within pathophysiological range. Then, imaging of L-anap labeled Nav1.5 in mammalian cells afforded characterization of unique L-anap spectra at different sites in the inactivation gate. Finally, using potassium-depolarization (K-depolarization) as rough means of voltage control, L-anap spectral shifts demonstrated conformational changes between the closed and open-inactivated states, which depended on the presence of the distal C-T (DCT). Site-specific L-anap labeling of the inactivation gate combined with spectral imaging and K-depolarization affords a general imaging assay to directly monitor conformational rearrangements of the Nav1.5 inactivation gate in channels expressed in live mammalian cells. While interactions with the DCT are specifically probed, this general assay provides an opportunity to bring necessary unification of ideas about VGSC inactivation, as well as insight on outstanding questions of VGSC regulation.
A transient phase in cosmological evolution : A multi-fluid approximation for a quasi-thermodynamics equilibrium
Creators: name: Osano, Bob
name: Oreta, Timothy
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: This article presents the study of a multi-species fluid characterised by a freeze-out or break-away of one or more species. Whereas single-fluid approximation suffices for modelling of the pre {\it freeze-out} period, multi-fluid approximation is required for the post freeze-out period. Embedded in this is a transition period where neither one of the two approximations is singly appropriate. We examine the thermodynamics of this fluid and find that the second law holds before, during and after the freeze-out. Our application to cosmological modelling involving interacting dark-section species indicates that the species' equations of state are modified.
description: 11 pages, 2 figures
Conical metrics on Riemann surfaces, II: spherical metrics
Creators: name: Mazzeo, Rafe
name: Zhu, Xuwen
Publisher: name: arXiv
Year: 2019
Subjects: subject: Differential Geometry (math.DG)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We continue our study, initiated in our earlier paper, of Riemann surfaces with constant curvature and isolated conic singularities. Using the machinery developed in that earlier paper of extended configuration families of simple divisors, we study the existence and deformation theory for spherical conic metrics with some or all of the cone angles greater than $2π$. Deformations are obstructed precisely when the number $2$ lies in the spectrum of the Friedrichs extension of the Laplacian. Our main result is that, in this case, it is possible to find a smooth local moduli space of solutions by allowing the cone points to split. This analytic fact reflects geometric constructions in papers by Mondello and Panov.
description: Final version accepted by Int. Math. Res. Not
Proof of a determinant evaluation conjectured by Bombieri, Hunt and van der Poorten
Creators: name: Krattenthaler, Christian
name: Zeilberger, Doron
Publisher: name: arXiv
Year: 1998
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: A determinant evaluation is proven, a special case of which establishes a conjecture of Bombieri, Hunt, and van der Poorten (Experimental Math\. {\bf 4} (1995), 87--96) that arose in the study of Thue's method of approximating algebraic numbers.
description: AMSTeX
Irreducibility and factorizations in monoid rings
Creators: name: Gotti, Felix
Publisher: name: arXiv
Year: 2019
Subjects: subject: Commutative Algebra (math.AC)
subject: FOS: Mathematics
subject: Primary: 20M25, 13F15, Secondary: 13A05

description: For an integral domain $R$ and a commutative cancellative monoid $M$, the ring consisting of all polynomial expressions with coefficients in $R$ and exponents in $M$ is called the monoid ring of $M$ over $R$. An integral domain is called atomic if every nonzero nonunit element can be written as a product of irreducibles. In the investigation of the atomicity of integral domains, the building blocks are the irreducible elements. Thus, tools to prove irreducibility are crucial to study atomicity. In the first part of this paper, we extend Gauss's Lemma and Eisenstein's Criterion from polynomial rings to monoid rings. An integral domain $R$ is called half-factorial (or an HFD) if any two factorizations of a nonzero nonunit element of $R$ have the same number of irreducible elements (counting repetitions). In the second part of this paper, we determine which monoid algebras with nonnegative rational exponents are Dedekind domains, Euclidean domains, PIDs, UFDs, and HFDs. As a side result, we characterize the submonoids of $(\mathbb{Q}_{\ge 0},+)$ satisfying a dual notion of half-factoriality known as other-half-factoriality.
description: 10 pages
Additional file 7: of Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation
Creators: name: Costa, Elodie Da
name: Armaos, Gregory
name: McInnes, Gabrielle
name: Beaudry, Annie
name: Moquin-Beaudry, Gaël
name: Bertrand-Lehouillier, Virginie
name: Caron, Maxime
name: Richer, Chantal
name: St-Onge, Pascal
name: Johnson, Jeffrey
name: Nevan Krogan
name: Sai, Yuka
name: Downey, Michael
name: Moutih Rafei
name: Boileau, Meaghan
name: Eppert, Kolja
name: Flores-Díaz, Ema
name: Haman, André
name: Hoang, Trang
name: Sinnett, Daniel
name: Beauséjour, Christian
name: McGraw, Serge
name: Raynal, Noël
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Figure S6. Proscillaridin A Treatment Downregulated MYC Target Genes That Are Marked By H3K27ac In Promoter Regions. Map of A co-expression pathways and B protein-protein physical interactions of MYC target genes marked by H3K27ac in untreated MOLT-4 cells. (PDF 1418 kb)
Experiment and Theory in Computations of the He Atom Ground State
Creators: name: Schwartz, Charles
Publisher: name: arXiv
Year: 2002
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Extensive variational computations are reported for the ground state energy of the non-relativistic two-electron atom. Several different sets of basis functions were systematically explored, starting with the original scheme of Hylleraas. The most rapid convergence is found with a combination of negative powers and a logarithm of the coordinate s = r_{1}+ r_{2}. At N=3091 terms we pass the previous best calculation (Korobov's 25 decimal accuracy with N=5200 terms) and we stop at N=10257 with E = -2.90372 43770 34119 59831 11592 45194 40444 ... Previous mathematical analysis sought to link the convergence rate of such calculations to specific analytic properties of the functions involved. The application of that theory to this new experimental data leaves a rather frustrating situation, where we seem able to do little more than invoke vague concepts, such as ``flexibility.'' We conclude that theoretical understanding here lags well behind the power of available computing machinery.
description: 15 pages