cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Resolved imaging of an extrasolar radiation belt around an ultracool dwarf
Creators: name: Kao, Melodie M.
name: Mioduszewski, Amy J.
name: Villadsen, Jackie
name: Shkolnik, Evgenya L.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Radiation belts are present in all large-scale Solar System planetary magnetospheres: Earth, Jupiter, Saturn, Uranus, and Neptune. These persistent equatorial zones of trapped high energy particles up to tens of MeV can produce bright radio emission and impact the surface chemistry of close-in moons. Recent observations confirm planet-like radio emission such as aurorae from large-scale magnetospheric current systems on very low mass stars and brown dwarfs. These objects, collectively known as ultracool dwarfs, also exhibit quiescent radio emission hypothesized to trace stellar coronal flare activity or extrasolar radiation belt analogs. Here we present high resolution imaging of the ultracool dwarf LSR J1835+3259 demonstrating that this radio emission is spatially resolved and traces a long-lived, double-lobed, and axisymmetric structure similar in morphology to the Jovian radiation belts. Up to 18 ultracool dwarf radii separate the two lobes. This structure is stably present in three observations spanning >1 year. We infer a belt-like distribution of plasma confined by the magnetic dipole of LSR J1835+3259, and we estimate ~15 MeV electron energies that are consistent with those measured in the Jovian radiation belts. Though more precise constraints require higher frequency observations, a unified picture where radio emissions in ultracool dwarfs manifest from planet-like magnetospheric phenomena has emerged.
 Submitted, under review.
description: Fixed a reference mix-up and clarified in abstract that this manuscript is currently under review
Novel supercell compounds of layered Bi-Rh-O with $p$-type metallic conduction materialized as a thin film form
Creators: name: Ohno, M.
name: Fujita, T. C.
name: Masutake, Y.
name: Kumigashira, H.
name: Kawasaki, M.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Layered oxides have been intensively studied due to their high degree of freedom in designing various electromagnetic properties and functionalities. While Bi-based layered supercell (LSC) compounds [Bi$_n$O$_{n+δ}$]-[$M$O$_2$] ($M$ = Mn, Mn/Al, Mn/Fe, or Mn/Ni; $n=2, 3$) are a group of prospective candidates, all of the reported compounds are insulators. Here, we report on the synthesis of two novel metallic LSC compounds [Bi$_{n}$O$_{n+δ}$]-[RhO$_2$] ($n=2, 3$) by pulsed laser deposition and subsequent annealing. With tuning the thickness of the sublattice from Bi$_2$O$_{2+δ}$ to Bi$_3$O$_{3+δ}$, a dimensionality-dependent electrical transport is revealed from a conventional metallic transport in $n=2$ to a localized transport in $n=3$. Our successful growth will be an important step for further exploring novel layered oxide compounds.
Code Staging in GNU Guix
Creators: name: Courtès, Ludovic
Publisher: name: arXiv
Year: 2017
Subjects: subject: Programming Languages (cs.PL)
subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: GNU Guix is a " functional " package manager that builds upon earlier work on Nix. Guix implements high-level abstractions such as packages and operating system services as domain-specic languages (DSLs) embedded in Scheme. It also implements build actions and operating system orchestration in Scheme. This leads to a multi-tier programming environment where embedded code snippets are staged for eventual execution. This paper presents G-expressions or " gexps ", the staging mechanism we devised for Guix. We explain our journey from traditional Lisp S-expressions to G-expressions, which augment the former with contextual information and ensure hygienic code staging. We discuss the implementation of gexps and report on our experience using them in a variety of operating system use cases-from package build processes to system services. Gexps provide a novel way to cover many aspects of OS connguration in a single, multi-tier language, while facilitating code reuse and code sharing .
description: 16th ACM SIGPLAN International Conference on Generative Programming: Concepts and Experiences (GPCE'17), Oct 2017, Vancouver, Canada
title: Development of Corramycin as an antibiotic against Gram-negative bacteria
Creators: name: Bergamo, Diletta
name: Fries, F.
name: Wirschem, N.
name: Kany, A.
name: Hermann, J.
name: Kazmaier, U.
name: Hirsch, A.
name: Müller, R.
Publisher: name: Fachinformationsdienst für Pharmazie
Year: 2025
Subjects: subject: 615
subject: 610

description: Corramycin is a linear peptide with a distinct structure, isolated from the myxobacterium Corallococcus coralloides spp., and features novel amino acids like methylated β-hydroxy-D-histidine. This compound exhibits strong antibacterial activity (in the low µM range) against Gram-negative pathogens of the Enterobacteriaceae family, including clinically relevant strains of multidrug resistant E. coli. Recently, we also discovered that it shows promising efficacy against Mycobacterium tuberculosis (Mtb), with sub- to low-µM activity. The unique structure of corramycin, along with its lack of cross-resistance, points to a novel mechanism of action. Although the precise molecular target remains unclear, extensive resistance studies have shown an induction of the SOS response, suggesting an inhibition of DNA synthesis. Furthermore, there is evidence that bacterial gyrase may be involved in its mechanism of action. To confirm the target and assess binding interactions, techniques such as target fishing and biophysical assays will be employed, and specific chemical tools for this purpose are currently being synthesized. Due to the difficulty of producing corramycin through fermentation or heterologous expression, a complete synthetic route has been optimized. The C-terminal pentapeptide is synthesized using solid-phase peptide synthesis, supported by the Fmoc strategy. The N-terminal pharmacophore, highly functionalized, is created using stereoselective synthetic methods for the non-proteinogenic component and sequential peptide coupling in solution. The final natural product is formed by chemically ligating the two synthetic fragments and performing global deprotection. Moving forward, the aim is to modify the pharmacophore through total synthesis and medicinal-chemistry optimization to create more potent derivatives with enhanced pharmacokinetics, increased activity against Gram-negative and Mtb. These derivatives will then undergo evaluations for antibacterial activity, ADMET profiling, in vivo PK/PD studies, and toxicity testing.
Existence and rotatability of the two-colored Jones-Wenzl projector
Creators: name: Hazi, Amit
Publisher: name: arXiv
Year: 2023
Subjects: subject: Representation Theory (math.RT)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: Primary 20G42, 20F55, Secondary 11R18

description: The two-colored Temperley-Lieb algebra $2\mathrm{TL}_R({}_s {n})$ is a generalization of the Temperley-Lieb algebra. The analogous two-colored Jones-Wenzl projector $\mathrm{JW}_R({}_s {n}) \in 2\mathrm{TL}_R({}_s {n})$ plays an important role in the Elias-Williamson construction of the diagrammatic Hecke category. We give conditions for the existence and rotatability of $\mathrm{JW}_R({}_s {n})$ in terms of the invertibility and vanishing of certain two-colored quantum binomial coefficients. As a consequence, we prove that Abe's category of Soergel bimodules is equivalent to the diagrammatic Hecke category in complete generality.
description: 16 pages, many figures, best viewed in color
Theory of Large Intrinsic Spin Hall Effect in Iridate Semimetals
Creators: name: Patri, Adarsh S.
name: Hwang, Kyusung
name: Lee, Hyun-Woo
name: Kim, Yong Baek
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We theoretically investigate the mechanism to generate large intrinsic spin Hall effect in iridates or more broadly in 5d transition metal oxides with strong spin-orbit coupling. We demonstrate such a possibility by taking the example of orthorhombic perovskite iridate with nonsymmorphic lattice symmetry, SrIrO$_3$, which is a three-dimensional semimetal with nodal line spectrum. It is shown that large intrinsic spin Hall effect arises in this system via the spin-Berry curvature originating from the nearly degenerate electronic spectra surrounding the nodal line. This effect exists even when the nodal line is gently gapped out, due to the persistent nearly degenerate electronic structure, suggesting a distinct robustness. The magnitude of the spin Hall conductivity is shown to be comparable to the best known example such as doped topological insulators and the biggest in any transition metal oxides. To gain further insight, we compute the intrinsic spin Hall conductivity in both of the bulk and thin film systems. We find that the geometric confinement in thin films leads to significant modifications of the electronic states, leading to even bigger spin Hall conductivity in certain cases. We compare our findings with the recent experimental report on the discovery of large spin Hall effect in SrIrO$_3$ thin films.
description: 14 pages, 19 figures, 4 tables
Policy Brief for Ministries of Education: Nature-Based Climate Shelters in Schools
Creators: name: Grand-Meyer, Eddy
name: Ivanova, Ivelina
name: Gras-Velazquez, Agueda
Publisher: name: Zenodo
Year: 2025
Subjects: policy brief
recommendations
ministries of education
nature-based solutions
nature-based climate chelters
COOLSCHOOLS

description: This Policy brief is informed by research done by the COOLSCHOOLS project, analysing the co-benefits of implementing nature-based solutions (NBS) for climate adaptation in “nature-based climate shelters in schools” (NBCSS). Along with best practices examined across four case study cities (Barcelona, Brussels, Paris, Rotterdam), findings were “translated” by the project into pedagogical resources (i.e. Guidelines for schools, a MOOC for teachers, and a user-friendly action plan to help educators plan schoolyard transformations or greening initiatives in schools).
Classicality and Quantum Break-Time for Cosmic Axions
Creators: name: Dvali, Gia
name: Zell, Sebastian
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the length of the period of validity of a classical description for the cosmic axion field. To this end, we first show that we can understand the oscillating axion solution as expectation value over an underlying coherent quantum state. Once we include self-interaction of the axion, the quantum state evolves so that the expectation value over it starts to deviate from the classical solution. The time-scale of this process defines the quantum break-time. For the hypothetical dark matter axion field in our Universe, we show that quantum break-time exceeds the age of the Universe by many orders of magnitude. This conclusion is independent of specific properties of the axion model. Thus, experimental searches based on the classical approximation of the oscillating cosmic axion field are fully justified. Additionally, we point out that the distinction of classical nonlinearities and true quantum effects is crucial for calculating the quantum break-time in any system. Our analysis can also be applied to other types of dark matter that are described as classical fluids in the mean field approximation.
description: 25 pages, 2 figures
Equivalence of Causal Models with Latent Variables
Creators: name: Spirtes, Peter
name: Verma, Thomas
Publisher: name: Carnegie Mellon University
Year: 1992
Subjects: subject: Philosophy
subject: FOS: Philosophy, ethics and religion

description: Peter Spirtes and Thomas Verma. Equivalence of Causal Models with Latent Variables.
Is there a correlation between children’s outdoor active mobility behaviour and neighbourhood safety? A systematic review of the evidence
Creators: name: Zougheibe, Roula
name: Gudes, Ori
name: Norman, Richard
name: Jepson, Beverley
name: Dewan, Ashraf
Publisher: name: figshare
Year: 2021
Subjects: subject: 111704 Community Child Health
subject: FOS: Health sciences
subject: 111716 Preventive Medicine
subject: 111499 Paediatrics and Reproductive Medicine not elsewhere classified
subject: FOS: Clinical medicine
subject: 111403 Paediatrics

description: Systematic review of evidence on 29 studies showed that Children are restricted by perception of safety. Encouraging children’s active travel may require future strategies to address characteristics relevant to types of the neighbourhood that promote a high sense of personal safety. Children and parents may embrace other types of active mobility behaviour if road danger is mitigated. Sex/gender and age-specific interventions and redesign of public places could lead to child-friendly cities. Future studies may benefit from adopting validated measurement methods and fill existing research gaps.
Towards a supersymmetric non-abelian Born-Infeld theory
Creators: name: Bergshoeff, E.
name: de Roo, M.
name: Sevrin, A.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We define an iterative procedure to obtain a non-abelian generalization of the Born-Infeld action. This construction is made possible by the use of the severe restrictions imposed by kappa-symmetry. We have calculated all bosonic terms in the action up to terms quartic in the Yang-Mills field strength and all fermion bilinear terms up to terms cubic in the field strength. Already at this order the fermionic terms do not satisfy the symmetric trace-prescription.
description: 9 pp. Latex, to appear in the proceedings of the Strings 2000 conference
How does the cosmic web impact assembly bias?
Creators: name: Musso, M.
name: Cadiou, C.
name: Pichon, C.
name: Codis, S.
name: Kraljic, K.
name: Dubois, Y.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The mass, accretion rate and formation time of dark matter haloes near proto-filaments (identified as saddle points of the potential) are analytically predicted using a conditional version of the excursion set approach in its so-called "upcrossing" approximation. The model predicts that at fixed mass, mass accretion rate and formation time vary with orientation and distance from the saddle, demonstrating that assembly bias is indeed influenced by the tides imposed by the cosmic web. Starved, early forming haloes of smaller mass lie preferentially along the main axis of filaments, while more massive and younger haloes are found closer to the nodes. Distinct gradients for distinct tracers such as typical mass and accretion rate occur because the saddle condition is anisotropic, and because the statistics of these observables depend on both the conditional means and their covariances. The theory is extended to other critical points of the potential field. The response of the mass function to variations of the matter density field (the so-called large scale bias) is computed, and its trend with accretion rate is shown to invert along the filament. The signature of this model should correspond at low redshift to an excess of reddened galactic hosts at fixed mass along preferred directions, as recently reported in spectroscopic and photometric surveys and in hydrodynamical simulations. The anisotropy of the cosmic web emerges therefore as a significant ingredient to describe jointly the dynamics and physics of galaxies, e.g. in the context of intrinsic alignments or morphological diversity.
description: 30 pages, 23 figures, Submitted to MNRAS
title: ADCO, Comptes du Petit-Cîteaux (1477-1491) (11 H 1179), f. 00516
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Archives Départementales De La Côte D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: comptes

description: Comptes du Petit-Cîteaux (1477-1491), Archives départementales de la Côte-d'Or, (11 H 1179). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Comptes du Petit-Cîteaux (1477-1491), Archives départementales de la Côte-d'Or, (11 H 1179), f. 00516, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
Tunable terahertz emission from difference-frequency in biased superlattices
Creators: name: Liu, Ren-Bao
name: Zhu, Bang-Fen
Publisher: name: arXiv
Year: 2003
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The terahertz emission from difference-frequency in biased superlattices is calculated with the excitonic effect included. Owing to the doubly resonant condition and the excitonic enhancement, the typical susceptibility can be as large as $10^{-5}$ m/V. The doubly resonant condition can always be realized by adjusting the bias voltage and the laser frequencies, thus the in-situ tunable emission is efficient in a range of several terahertz. Continuous wave operation with 1% quantum efficiency and $μ$W output power is feasible as the signal absorption in undoped superlattices is negligible.
description: 3pages 2figures
title: ADCO, Cartulaire de Saint-Étienne de Dijon (XIVe siècle), Cart. 24 (G 137), 31 folios, f. 0066
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Saint-Étienne de Dijon (XIVe siècle), Archives départementales de la Côte-d'Or, Cart. 24 (G 137), 31 folios, f. 0066, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Saint-Étienne de Dijon (XIVe siècle), Archives départementales de la Côte-d'Or, Cart. 24 (G 137), 31 folios, f. 0066, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Photoproduction of pentaquark cascades from nucleons
Creators: name: Liu, W.
name: Ko, C. M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The cross sections for production of pentaquark $Ξ^+_5$ from the reaction $γp\to K^0K^0Ξ^+_5$ and $Ξ^{--}_5$ from the reaction $γn\to K^+K^+Ξ^{--}_5$ are evaluated in a hadronic model that includes their couplings to both $Σ\bar K$ and $Σ\bar K^*$. With these coupling constants determined from the empirical $πNN(1710)$ and $ρNN(1710)$ coupling constants by assuming that $Ξ^+_5$, $Ξ^{--}_5$, and N(1710) belong to the same antidecuplet of spin 1/2 and positive parity, and using form factors at strong interaction vertices similar to those for pentaquark $Θ^+$ production in photonucleon reactions, we obtain a cross section of about 0.03-0.6 nb for the reaction $γp\to K^0K^0Ξ^+_5$ and about 0.1-0.6 nb for the reaction $γn\to K^+K^+Ξ^{--}_5$ at photon energy $E_γ=4.5$ GeV, depending on the value of the coupling constant $g_{K^*ΣΞ_5}$.
description: 14 pages, 5 figures
Belnap-Dunn logic and query answering in inconsistent databases with null values
Creators: name: Middelburg, C. A.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Databases (cs.DB)
subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences
subject: F.4.1; H.2.3; H.2.4

description: This paper concerns an expansion of first-order Belnap-Dunn logic, named $\mathrm{BD}^{\supset,\mathsf{F}}$, and an application of this logic in the area of relational database theory. The notion of a relational database, the notion of a query applicable to a relational database, and several notions of an answer to a query with respect to a relational database are considered from the perspective of this logic, taking into account that a database may be an inconsistent database or a database with null values. The chosen perspective enables among other things the definition of a notion of a consistent answer to a query with respect to a possibly inconsistent database without resort to database repairs. For each of the notions of an answer considered, being an answer to a query with respect to a database of the kind considered is decidable.
description: 26 pages; revision of v1, presentation improved at several places and DOIs added to the papers in the references. arXiv admin note: text overlap with arXiv:2301.10555
From Bosonic Topological Transition to Symmetric Fermion Mass Generation
Creators: name: You, Yi-Zhuang
name: He, Yin-Chen
name: Vishwanath, Ashvin
name: Xu, Cenke
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The bosonic topological transition (BTT) is a quantum critical point between the bosonic symmetry protected topological phase and the trivial phase. In this work, we derive a description of this transition in terms of compact quantum electrodynamics (QED) with four fermion flavors ($N_f=4$). This allows us to describe the transition in a lattice model with the maximal microscopic symmetry: an internal SO(4) symmetry. Within a systematic renormalization group analysis, we identify the critical point with the desired O(4) emergent symmetry and all expected deformations. By lowering the microscopic symmetry we recover the previous $N_f=2$ non-compact QED description of the BTT. Finally, by merging two BTTs we recover a previously discussed theory of symmetric mass generation, as an SU(2) quantum chromodynamics-Higgs theory with $N_f=4$ flavors of SU(2) fundamental fermions and one SU(2) fundamental Higgs boson. This provides a consistency check on both theories.
description: 15 pages + references, 6 figures
On the sources of the late integrated Sachs-Wolfe effect
Creators: name: Fullana, Marius J.
name: Saez, Diego
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In some scenarios, the peculiar gravitational potential of linear and mildly nonlinear structures depends on time and, as a result of this dependence, a late integrated Sachs-Wolfe effect appears. Here, an appropriate formalism is used which allows us to improve on the analysis of the spatial scales and locations of the main cosmological inhomogeneities producing this effect. The study is performed in the framework of the currently preferred flat model with cosmological constant, and it is also developed in an open model for comparisons. Results from this analysis are used to discuss the contribution of Great Attractor-like objects, voids, and other structures to the CMB anisotropy.
description: 25 pages, 4 figures, accepted for publication in New Astronomy
X-CANIDS: Signal-Aware Explainable Intrusion Detection System for Controller Area Network-Based In-Vehicle Network
Creators: name: Jeong, Seonghoon
name: Lee, Sangho
name: Lee, Hwejae
name: Kim, Huy Kang
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cryptography and Security (cs.CR)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Controller Area Network (CAN) is an essential networking protocol that connects multiple electronic control units (ECUs) in a vehicle. However, CAN-based in-vehicle networks (IVNs) face security risks owing to the CAN mechanisms. An adversary can sabotage a vehicle by leveraging the security risks if they can access the CAN bus. Thus, recent actions and cybersecurity regulations (e.g., UNR 155) require carmakers to implement intrusion detection systems (IDSs) in their vehicles. The IDS should detect cyberattacks and provide additional information to analyze conducted attacks. Although many IDSs have been proposed, considerations regarding their feasibility and explainability remain lacking. This study proposes X-CANIDS, which is a novel IDS for CAN-based IVNs. X-CANIDS dissects the payloads in CAN messages into human-understandable signals using a CAN database. The signals improve the intrusion detection performance compared with the use of bit representations of raw payloads. These signals also enable an understanding of which signal or ECU is under attack. X-CANIDS can detect zero-day attacks because it does not require any labeled dataset in the training phase. We confirmed the feasibility of the proposed method through a benchmark test on an automotive-grade embedded device with a GPU. The results of this work will be valuable to carmakers and researchers considering the installation of in-vehicle IDSs for their vehicles.
description: This is the Accepted version of an article for publication in IEEE TVT
title: Simultaneous Determination of 3-Methoxy-4-Hydroxyphenyl-Glycol, Homovanillic Acid, and 5-Hydroxyindoleacetic Acid in Plasma by High Performance Liquid Chromatography
Creators: name: Tseng, Yung-Te
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1989

description: A rapid, reliable, and sensitive method for simultaneous determination of 3-methoxy-4-hydroxyphenylglycol (MHPG), Homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5- HIAA) in plasma is described. The method is based on high performance liquid chromatography with electrochemical detection. Samples were filtered with Amicon Centrifree micropartition systems and extracted with organic solvent before chromatography. Chromatographic separation of sample components was achieved isocratically in a C18 reverse-phase column. Quantitation was performed by measuring the peak height ratios of the sample components to an internal standard. Analytical recoveries ranged from 50.78 (SD 4.2%) to 67.94 (SD 3.28). Within-run coefficient of variations (CVs) ranged from 3.78 to 8.3%. Between-run CVs ranged from 4.58 to 11.34. The whole procedure can be completed within 1 hr and 20 min. The method is suitable for both clinical and research applications.
Monopoles and dyons in SO(3) gauged Skyrme models
Creators: name: Brihaye, Yves
name: Hartmann, Betti
name: Tchrakian, D. H.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Three dimensional SO(3) gauged Skyrme models characterised by specific potentials imposing special asymptotic values on the chiral field are considered. These models are shown to support finite energy solutions with nonvanishing magnetic and electrix flux, whose energies are bounded from below by two distinct charges - the magnetic (monopole) charge and a non-integer version of the Baryon charge. Unit magnetic charge solutions are constructed numerically and their properties characterised by the chosen asymptotics and the Skyrme coupling are studied. For a particular value of the chosen asymptotics, charge-2 axially symmetric solutions are also constructed and the attractive nature of the like-monopoles of this system are exhibited. As an indication towards the possible existence of large clumps of monopoles, some consideration is given to axially symmetric monopoles of charges-2,3,4.
description: 15 pages, 4 Postscript figures
Teleportation of Post-Selected Quantum States
Creators: name: Collins, Daniel
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Teleportation allows Alice to send a pre-prepared quantum state to Bob using only pre-shared entanglement and classical communication. Here we show that it is possible to teleport a state which is also $\it{post}$-selected. Post-selection of a state $Φ$ means that after Alice has finished her experiment she performs a measurement and only keeps runs of the experiment where the measurement outcome is $Φ$. We also demonstrate pre and post-selected $\it{port}$-based teleportation. Finally we use these protocols to perform instantaneous non-local quantum computation on pre and post-selected systems, and significantly reduce the entanglement required to instantaneously measure an arbitrary non-local variable of spatially separated pre and post-selected systems.
description: 8 pages, 7 figures, updated version accepted for publication in Quantum
Sequence of Potentials Interpolating between the U(5) and E(5) Symmetries
Creators: name: Bonatsos, Dennis
name: Lenis, D.
name: Minkov, N.
name: Raychev, P. P.
name: Terziev, P. A.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: It is proved that the potentials of the form $β^{2n}$ (with $n$ being integer) provide a ``bridge'' between the U(5) symmetry of the Bohr Hamiltonian with a harmonic oscillator potential (occuring for $n=1$) and the E(5) model of Iachello (Bohr Hamiltonian with an infinite well potential, materialized for infinite $n$). Parameter-free (up to overall scale factors) predictions for spectra and B(E2) transition rates are given for the potentials $β^4$, $β^6$, $β^8$, corresponding to $R_4=E(4)/E(2)$ ratios of 2.093, 2.135, 2.157 respectively, compared to the $R_4$ ratios 2.000 of U(5) and 2.199 of E(5). Hints about nuclei showing this behaviour, as well as about potentials ``bridging'' the E(5) symmetry with O(6) are briefly discussed. A note about the appearance of Bessel functions in the framework of E(n) symmetries is given as a by-product.
description: LaTeX, 17 pages, 9 postscript figures
Roper resonances and quasi-normal modes of Skyrmions
Creators: name: Adam, C.
name: Haberichter, M.
name: Romanczukiewicz, T.
name: Wereszczynski, A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Radial vibrations of charge one hedgehog Skyrmions in the full Skyrme model are analysed. We investigate how the properties of the lowest resonance modes (quasi normal modes) - their frequencies and widths - depend on the form of the potential (value of the pion mass as well as the addition of further potentials) and on the inclusion of the sextic term. Then we consider the inverse problem, where certain values for the frequencies and widths are imposed, and the field theoretic Skyrme model potential giving rise to them is reconstructed. This latter method allows to reproduce the physical Roper resonances, as well as further physical properties of nucleons, with high precision.
description: LaTex, 24 pages, 18 figures
The late afterglow and host galaxy of GRB 990712
Creators: name: Hjorth, Jens
name: Holland, Stephen
name: Courbin, Frederic
name: Dar, Arnon
name: Olsen, Lisbeth F.
name: Scodeggio, Marco
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present deep HST imaging, as well as ground-based imaging and spectroscopy, of the optical afterglow associated with the long-duration gamma-ray burst GRB 990712 and its host galaxy. The data were obtained 48--123 days after the burst occurred. The magnitudes of the host (R = 21.9, V = 22.5) and optical afterglow (R = 25.4, V = 25.8, 47.7 days after the burst) favor a scenario where the optical light follows a pure power-law decay with an index of alpha ~ -1.0. We find no evidence for a contribution from a supernova like SN1998bw. This suggests that either there are multiple classes of long-duration gamma-ray bursts, or that the peak luminosity of the supernova was > 1.5 mag fainter than SN1998bw. The HST images and EFOSC2 spectra indicate that the gamma-ray burst was located in a bright, extended feature (possibly a star-forming region) 1.4 kpc from the nucleus of a 0.2 L^*_B galaxy at z = 0.434, possibly a Seyfert 2 galaxy. The late-time afterglow and host galaxy of GRB 990712 bear some resemblance to those of GRB 970508.
description: 7 pages, 2 figures, to appear in ApJL (last author name corrected in revised version)
Entanglement Trajectory and its Boundary
Creators: name: Lin, Ruge
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In this article, we present a novel approach to investigating entanglement in the context of quantum computing. Our methodology involves analyzing reduced density matrices at different stages of a quantum algorithm's execution and representing the dominant eigenvalue and von Neumann entropy on a graph, creating an "entanglement trajectory." To establish the trajectory's boundaries, we employ random matrix theory. Through the examination of examples such as quantum adiabatic computation, the Grover algorithm, and the Shor algorithm, we demonstrate that the entanglement trajectory remains within the established boundaries, exhibiting unique characteristics for each example. Moreover, we show that these boundaries and features can be extended to trajectories defined by alternative entropy measures. The entanglement trajectory serves as an invariant property of a quantum system, maintaining consistency across varying situations and definitions of entanglement. Numerical simulations accompanying this research are available via open access.
Density of States and Tachyons in Open and Closed String Theory
Creators: name: Niarchos, Vasilis
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this note we reexamine the possibility of constructing stable non-supersymmetric theories that exhibit an exponential density of states. For weakly coupled closed strings there is a general theorem, according to which stable theories with an exponential density of states must exhibit an almost exact cancellation of spacetime bosons and fermions (not necessarily level by level). We extend this result to open strings by showing that if the above cancellation between bosons and fermions does not occur, the open strings do not decouple from a closed string tachyon even in the NCOS scaling limit. We conclude with a brief comment on the proposed generalization of the AdS/CFT correspondence to non-supersymmetric theories.
description: 11 pages, harvmac, v2: improved discussion, references added, v3: version published in JHEP
Ground State Bands of the E(5) and X(5) Critical Symmetries Obtained from Davidson Potentials through a Variational Procedure
Creators: name: Bonatsos, Dennis
name: Lenis, D.
name: Minkov, N.
name: Petrellis, D.
name: Raychev, P. P.
name: Terziev, P. A.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Davidson potentials of the form $β^2 +β_0^4/β^2$, when used in the original Bohr Hamiltonian for $γ$-independent potentials bridge the U(5) and O(6) symmetries. Using a variational procedure, we determine for each value of angular momentum $L$ the value of $β_0$ at which the derivative of the energy ratio $R_L=E(L)/E(2)$ with respect to $β_0$ has a sharp maximum, the collection of $R_L$ values at these points forming a band which practically coincides with the ground state band of the E(5) model, corresponding to the critical point in the shape phase transition from U(5) to O(6). The same potentials, when used in the Bohr Hamiltonian after separating variables as in the X(5) model, bridge the U(5) and SU(3) symmetries, the same variational procedure leading to a band which practically coincides with the ground state band of the X(5) model, corresponding to the critical point of the U(5) to SU(3) shape phase transition. A new derivation of the Holmberg-Lipas formula for nuclear energy spectra is obtained as a by-product.
description: LaTeX, 12 pages, 4 postscript figures
Cut-off radii of galactic disks: A statistical study on the truncation of galactic disks
Creators: name: Pohlen, M.
name: Dettmar, R. -J.
name: Luetticke, R.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the analysis of a CCD survey of 31 nearby (<= 110 Mpc) edge-on spiral galaxies. The three-dimensional one-component best fit models provide their disk-scalelengths h and for the first time their disk cut-off radii R_{co}. We confirm for this sample the existence of such sharp truncations, and find a significantly lower mean value of the distance independent ratio R_{co}/h =2.9 +- 0.7 than the standard value of 4.5 often used in the literature. Our data show no correlation of these parameters with Hubble type, whereas we report a correlation between R_{co}/h and the distance based scalelength in linear units. Compared to the Milky Way we find only lower values of R_{co}/h, explained either by possible selection effects or by the completely different techniques used. We discuss our data in respect to present models for the origin of the cut-off radii, either as a relict of the galaxy formation process, or as an evolutionary phenomenon.
description: LaTeX, 4 pages, 2 figures
title: Design, Synthesis, and Evaluation of Novel Elastase (LasB) Inhibitors: A Promising Strategy to Combat Pseudomonas aeruginosa Virulence and Antibiotic Resistance
Creators: name: Amin, Ahmed
name: Jézéquel, G.
name: Kolling, D.
name: Schütz, C.
name: Kany, A.
name: Koehnke, J.
name: Haupenthal, J.
name: Hirsch, A.
Publisher: name: Fachinformationsdienst für Pharmazie
Year: 2025
Subjects: subject: 615
subject: 610

description: Antibiotic resistance is an important global health issue, and Pseudomonas aeruginosa is a pathogen that is particularly worrying due to its ability to become virulent and multidrug-resistant. One of the main mechanisms by which P. aeruginosa exerts its virulence is through the production of elastase (LasB), an extracellular metalloprotease involved in the disturbance of the host immune system. Several compounds have succeeded in suppressing LasB activity, but their lack of stability and selectivity has prevented further development. We have successfully designed and synthesized a series of compounds based on co-crystal structures, enhancing inhibitory activity. The results demonstrate their efficacy as very potent LasB inhibitors, with sub-nanomolar inhibition constants (IC50 = 0.49–7.7nM). Furthermore, these compounds have demonstrated good stability and selectivity over human off-targets. In addition to these achievements, we have strategically addressed plasma protein binding (PPB), lowering it to align with the lung exposure range. In addition to in vitro tests, promising results were obtained in in vivo PK studies, which paved the way to demonstrate in vivo efficacy and target engagement in a murine lung infection model. Our research provides evidence of the success of the design of a new LasB inhibitor class that can be optimized and further developed as a potential therapeutic to reduce P. aeruginosa virulence. Additional biological and pharmacological tests will be presented, which highlight the potential of these compounds as a new class of LasB inhibitors for the treatment of infections caused by P. aeruginosa.
title: TRPC5 in the context of neuropathic and inflammatory pain
Creators: name: Müller, Christian
name: Geisslinger, Gerd
name: Sisignano, Marco
Publisher: name: Fachinformationsdienst für Pharmazie
Year: 2025
Subjects: subject: 615
subject: 610

description: Background & Aims Chronic pain is a major health problem affecting 10-20% of the population worldwide. Because of unsatisfactory treatments with harsh side effects - especially for neuropathic pain patients - there is an emerging need for novel and innovative approaches. In context of different pain states, it is well known that TRP-channel superfamily contributes to pain hypersensitivity by sensitising pain relevant neurons. Unfortunately, they are in general too important for physiological sensations, which makes it difficult to target them. Because of this we want to focus on proteins that are not responsible for normal tactile pain and pain sensations but are upregulated in pathophysiological pain states respectively. Therefore, the transient receptor potential canonical channel 5 (TRPC5) was identified as potential candidate. To understand the responsibilities and the role in the development of pain we set our focus to TRPC5 in this study. TRPC5 is one of the seven mammalian TRPC proteins. Functionally, it is a non-selective calcium permeable cation channel which acts as homotetrameric or heteromultimeric assemblies with other TRPC proteins. Results In our study we first investigated the expression of TRPC5 target mRNA and protein levels in different pain relevant tissues of the treated animals. After triggering a chemotherapy induced peripheral neuropathy (CIPN) in vivo, we observed a significant increase in the expression of TRPC5 in neuronal tissue. Based on these results, we aimed to gain a deeper understanding of the role of TRPC5 in the development of neuropathic pain. Therefore, we first investigated the influence of different already known inhibitory modulators (AC1903, HC 070) of the channel in our cell system and confirmed earlier findings. Additionally, we screened several lipids to examine their interaction with the receptor. Our findings show that special lysophospholipids and eicosanoids can modulate the activity of the TRPC5 channel. We plan to further investigate these compounds on primary cell cultures from mice and their relevance in persistent pain states in vivo.
Fano Resonance in a Quantum Wire with a Side-coupled Quantum Dot
Creators: name: Kobayashi, Kensuke
name: Aikawa, Hisashi
name: Sano, Akira
name: Katsumoto, Shingo
name: Iye, Yasuhiro
Publisher: name: arXiv
Year: 2003
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We report a transport experiment on the Fano effect in a quantum connecting wire (QW) with a side-coupled quantum dot (QD). The Fano resonance occurs between the QD and the "T-shaped" junction in the wire, and the transport detects anti-resonance or forward scattered part of the wavefunction. While in this geometry it is more difficult to tune the shape of the resonance than in the previously reported Aharonov-Bohm-ring type interferometer, the resonance purely consists of the coherent part of transport. By utilizing this advantage, we have qualitatively explained the temperature dependence of the Fano effect by including the thermal broadening and the decoherence. We have also proven that this geometry can be a useful interferometer to measure the phase evolution of electrons at a QD.
description: REVTEX, 6 pages including 5 figures, final version
Confronting fuzzy dark matter with the rotation curves of nearby dwarf irregular galaxies
Creators: name: Bañares-Hernández, Andrés
name: Castillo, Andrés
name: Camalich, Jorge Martin
name: Iorio, Giuliano
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate phenomenologically the viability of fuzzy dark matter (FDM). We do this by confronting the predictions of the model, in particular, the formation of a solitonic core at the center of dark matter halos, with a homogeneous and robust sample of high-resolution rotation curves from the "LITTLE THINGS in 3D" catalog. This comprises a collection of isolated, dark matter dominated dwarf-irregular galaxies that provides an optimal benchmark for cosmological studies. We use a statistical framework based on Markov chain Monte Carlo techniques that allows us to extract relevant parameters such as the axion mass, the mass of the solitonic core, the mass of the dark matter halo and its concentration parameter with a rather loose set of priors except for the implementation of a core-halo relation that is predicted by simulations. The results of the fits are used to perform various diagnostics on the predictions of the model. FDM provides an excellent fit to the rotation curves of the "LITTLE THINGS in 3D" catalog, with axion masses determined from different galaxies clustering around $m_a\approx2\times10^{-23}$ eV. However, we find two major problems in our analysis. First, the data follow scaling relations of the properties of the core which are not consistent with the predictions of the soliton. This problem is particularly acute in the core radius - mass relation with a tension that, at face value, has a significance $\gtrsim5σ$. The second problem is related to the strong suppression of the linear power spectrum that is predicted by FDM for the axion mass preferred by the data. This can be constrained very conservatively by the galaxy counts in our sample, which leads to a tension exceeding again $5σ$. We estimate the effects of baryons in our analysis and discuss whether they could alleviate the tensions of the model with observations.
description: 22 pages, 9 figures, 3 tables
Analysis of kaon spectra at SIS energies - what remains from the KN potential
Creators: name: Hartnack, C.
name: Aichelin, J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study the reaction Au+Au at 1.48 AGeV and analyze the influence of the KN optical potential on cm spectra and azimuthal distributions at mid-rapidity. We find a significant change of the yields but only slight changes in the shapes of the distributions when turning off the optical potential. However, the spectra show contributions from different reaction times, where early kaons contribute stronger to higher momenta and late kaons to lower momenta. Azimuthal distributions of the kaons at mid-rapidity show a strong centrality dependence. Their shape is influenced by the KN optical potential as well as by re-scattering.
description: SQM 2003 proceedings, 4 figures, 6 pages