cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Andrea M. Kluxen / Julia Krieger (Hrsg.), Denkmalpflege in Mittelfranken 2014
Creators: name: Redaktion, Die
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Rezension zu: Andrea M. Kluxen / Julia Krieger (Hrsg.), Denkmalpflege in Mittelfranken 2014, Bad Windsheim: Delp-Verlag 2015, 151 Seiten, zahlreiche Farbabbildungen. ISBN 978-3-7689-0287-8.
description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 56 Nr. 1 (2015): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Regulation of eye development by frizzled signaling in Xenopus
Creators: name: Rasmussen, Jennifer Terry
Publisher: name: University of Utah
Year: 2012
Subjects: Xenopus - Development
Eye - Growth - Regulation

description: Eye development in both invertebrates and vertebrates is regulated by a network of highly conserved transcription factors.  However, it is not known what controls the expression of these factors to regulate early eye formation, and whether transmembrance signaling events are involved.  Her we establish a role for signaling via a member of the frizzled family of receptors in regulating early eye development.  We show that overexpression of Xenopus frizzled 3 (Xfz3), a receptor expressed during normal eye development, functions cell autonomously to promote ectopic eye formation, and can also perturb endogenous eye development.  Ectopic eye obtained with Xfz3 overexperession have a laminar organization similar to endogenous eyes and contain differentiated retinal cell types.  Ectopic eye formation is preceded by ectopic expression of transcription factors involved in early eye development, including Pax6, Rx and Otx2.  Conversely, targeted overexpression of a dominant-negative form of Xfz3 (Nxfz3), consisting of the soluble extracellular domain of the receptor, results in suppression of endogenous Pax6, Otx2 and Rx expression and suppression of endogenous eye development.  This effect can be rescued by co-expression of Xfz3.  Finally, overexpression of Kermit, a protein that interacts with the C-terminal intracellular domain of Xfz3, also blocks endogenous eye development, suggesting that signaling through Xfz3 or a related receptor is required for normal eye development.  In summary we show that frizzled signaling is both necessary and sufficient to regulate eye development in Xenopus.
Wnt/frizzled signaling in nervous system development
Creators: name: Van Raay, Terence John
Publisher: name: University of Utah
Year: 2012
Subjects: Growth and Development
Nervous System

description: The central nervous system is an amazingly complex structure. Understanding the process of lineage determination is one of the fundamental challenges facing developmental biologists. This dissertation is focused on deciphering the molecular mechanisms by which the wnt signaling pathway is involved in generating increasingly restricted neural progenitors from more multipotent precursors. Towards this aim, I took three approaches. First, I investigated the expression pattern of the wnt receptor, frizzled 9 (Mfz9), in mouse neural tube development. Specifically, I found that Mfz9 had an early, conserved expression pattern in the developing CNS when multipotent neuroepithelial precursors are becoming restricted to neuronal progenitors. Further, I demonstrated that Mfz9 protein was localized to these two progenitor pools and excluded from a glial restricted progenitor. This suggests that Mfz9 may have a role in neuroepithelial precursor to neuronal progenitor lineage determination.  Second, using the Xenopus retina as a model system, I sought to determine when and where the Wnt/|3-catenin pathway was active during retinogenesis. I determined that the Wnt/p-catenin was active in proliferating retinal precursors and in the more restricted neural retinoblasts.  Third, I sought to determine the role of Xenopus frizzled 5 (Xfz5) in retinogenesis which has an expression pattern restricted to the developing neural retina. I determined that Xfz5 is involved in the transition from the multipotent retinal precursor to the more restricted neural retinoblast. Knocking down Xfz5 function results in a dramatically reduced, but normal eye. This is likely due to a decrease in proliferation of neural retinoblasts. Further, inhibiting Xfz5 function results in a delay in the onset of both neurogenic and proneural genes in the neural retinoblasts. My data suggest that in the absence of Xfz5 function, the entire program in the initiation of the proliferating neural retinoblast is delayed. Collectively, these results enhance our understanding of lineage determination in the developing CNS, suggesting that wnt signaling may be important in the development of increasingly restricted progenitors.
Chemical composition and effect of Dysphania ambrosioides (L.) mosyakin & clemants essential oil on Biomphalaria tenagophila (D’Orbigny, 1835)
Creators: name: Ignacchiti, Mariana D. Costa
name: de Queiroz, Vagner Tebaldi
name: Martins, Isabella Vilhena Freire
name: Crico, Kamila B.
name: Gonçalves, Lara Vezula
name: Fazolo, Milena Busato
name: Frank, Henrique Oliveira
name: Costa, Adilson Vidal
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Dysphania ambrosioides (L.) Mosyakin & Clemants, known as santa maria herb, is a medicinal plant used on pest control and to treat parasitic diseases. Due to its potential for pest control, the aim of this work was to determine the chemical composition of D. ambrosioides essential oil and evaluate its molluscicidal effect on Biomphalaria tenagophila, which is an intermediate host for the Schistosoma mansoni trematode, that is responsible for causing human schistosomiasis. The essential oil extracted from its leaves showed 87% of (Z)-ascaridole and 100% of mortality against B. tenagophila at 10 ppm after 24 h of experiment. LC50 and LC90 values were, respectively, 2.40 (1.90-2.99) ppm and 8.75 (6.39-14.12) ppm. D. ambrosioides essential oil proved to be a promising natural molluscicide against schistosomiasis when compared with commercial products.
Peter Springer, Zwischen Mittelalter und Moderne. August Essenwein als Architekt, Bauhistoriker, Denkmalpfleger und Museumsmann
Creators: name: Wirth, Hermann
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Rezension zu: Peter Springer, Zwischen Mittelalter und Moderne. August Essenwein als Architekt, Bauhistoriker, Denkmalpfleger und Museumsmann, Braunschweig: Appelhans Verlag 2014. 612 Seiten, mit großenteils farbigen Abbildungen. ISBN 978-3-924553-01-2.
description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 56 Nr. 1 (2015): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Macrodactylini Kirby 1837
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae

description: MACRODACTYLINI Kirby, 1837
Key. Fuhrmann and Vaz-de-Mello 2017 (genera)
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 109, DOI: 10.5281/zenodo.3678492
Kopie einer Sonnenfleckenzeichnung, unnummeriert.
Chemisch vervielfältigte Kopie der Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.04.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Professional conceptions, commitments, and perceived dissonance among baccalaureate nurses
Creators: name: Mitchell, Ronald
Publisher: name: University of Utah
Year: 2012

description: The purposes of this study were to: (a) describe the extent to which baccalaureate nurses experience dissonance when a discrepancy exists between their professional conceptions, commitments, and behaviors; (b) identify which professional attribute (unique knowledge, service orientation, autonomy) contributed to the greatest amount of perceived dissonance; (c) describe the extent of work environment support for the enactment of professional behaviors; (d) identify nurses' levels of motivation and strategies used to reduce perceived dissonance; and (e) compare the professional conceptions and commitments of senior baccalaureate students and employed nurses. The research was based upon the cognitive dissonance theoretical framework and more specifically, on the assumption that nurses who are socialized into the professional role may encounter discrepancies between their professional conceptions and their actual behaviors in practice. A cross-sectional survey design was employed to gather information directly from employed nurses and senior nursing students. The survey was distributed to 759 registered nurses employed in five American Hospital Association (AHA) accredited hospital in two western states and to 55 students enrolled in two National League for Nursing (NLN) accredited baccalaureate programs in the same two western states. One hundred and thirty-five nurse surveys and 40 student surveys were returned, coded, and analyzed. Analysis of the data revealed moderate levels of perceived dissonance in employed nurses who believed that there were discrepancies between their professional conceptions, commitments, and behaviors, with the greatest amount of dissonance related to autonomy. Generally, nurses perceived their work environments as supportive of their professional behaviors; yet, they were also highly motivated to reduce the perceived dissonance that did exist. Nurses listed several strategies that they used in their attempts to reduce the perceived dissonance. The findings also suggested that there were similarities between the professional conceptions of employed nurses and senior students; however, the two groups differed significantly in the degree of commitment to professional practice with the students having higher commitment scores.
Sonnenfleckenzeichnung Nr. 22745.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.03.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
The evolutionary and ecological significance of phylloclade formation: A morpho-anatomical approach
Creators: name: Dörken, Veit M
name: Ladd, Philip G
name: Parsons, Robert
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3103
subject: Ecology
classificationCode: 3108
subject: Plant biology

description: Instead of leaves, in a few species the main photosynthetic organ is a flattened structure that can be a modified branch (e.g. Ruscus, Jacksonia) or a fused combination of branch and leaf tissue (e.g. Phyllocladus) called a phylloclade. The phylloclades of Phyllocladus lack xeromorphic features in their wet habitat. They are broad under the low light conditions as are those of Ruscus which can occur in forest understories. However Ruscus is also common in dry habitats and shows numerous xeromorphic features. In Jacksonia extensive sclerenchyma and thick cuticle protect the phylloclades from desiccation damage in xeric seasonal conditions. Despite former contrary definitions of phylloclades we advocate they be defined as pseudo-petiolate organs determinate in growth which arise from axillary buds in the axil of reduced leaves and resemble a leaf.
Microfluidic systems for the study of the Caenorhabditis Elegans worm
Creators: name: Liddiard, Erik
Publisher: name: University of Utah
Year: 2012
Subjects: Caenorhabditis elegans
Microfluidics
Screen
Sort
Worm

description: Two microfluidics devices are presented, which are used to further study of the Caenorhabditis elegans worm (C. elegans). The first device is a tool for ranking the muscle force between mutant and wild type strains of worms. The second device is a screening chip, which is designed to decrease the amount of time needed to screen the C. elegans worm, and does not require the use of anesthetics to immobilize them for imaging.  The muscle force tool operates by compressing a worm in a microchannel with a flexible Polydimethylsiloxane (PDMS) membrane. The force the membrane exerts on the worm is determined by air pressure controlled using a sensitive regulator. The method mimics the natural environment of the worm, where it must move through soil. Worms are tested by loading them into the chip and air pressure against the membrane is increased in increments until the worm becomes immobilized. To rank strains of worms according to muscle force, the pressures at which the worms become immobilized are compared. The chip operates on the hypothesis that a higher pressure indicates a greater muscle contraction force. The chip was tested using three strains of worms: a wild type and two strains with genetic knockouts of specific ion channels at the neuromuscular junction. Immobilization pressures are given for each strain.  The screening chip is designed to be operated on a confocal microscope, and is used for taking high magnification images and videos of the worms. To perform the screening process, the chip separates a single worm form a solution containing many worms using a tapered channel and filter. Second, the worm is immobilized for imaging using a flexible PDMS membrane, which compresses the worm against a cover slip. Third, the worm is transported to one of two holding containers. Worm movement through the device is controlled on screen through a custom computer program. This work discusses the design, fabrication and testing results of the microfluidic chips.
Eucalyptus kino: a treasure trove of polyphenols eradicating tumors in-vivo by elevating caspase-3 level, inhibiting TGF-β and NF-κb gene expression
Creators: name: Sabry, Omar M.
name: Sabry, Miral O.
name: El-Sonbaty, Sawsan M.
name: Meselhy, Khaled M.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Plant Biology

description: 30 secondary polyphenolic metabolites were characterised in Eucalyptus kino methanol extract using HPLC-MS/MS. The antitumor activity of the extract in combination with low level ionising radiation in female mice with solid tumors from inoculated Ehrlich ascites carcinoma cells was investigated. Tumor cell-inoculated mice received daily extract doses (100 mg/kg, 200 mg/kgBW) with or without a single exposure to 0.25 Gy γ-rays, and cis-platin as a reference anticancer drug. Changes in the tumor volume, oxidative state, levels of caspase-3, TGF-β and Nf-κB were assessed by q-PCR. Surprisingly, a dose of 200 mg/kg extract together with γ-radiation remarkably reduced the tumor volume, improved the oxidative and apoptotic biomarker levels. In conclusion, results showed that a combination of kino extract with low level γ-radiation synergistically reduced tumor progression due to the antioxidant and anti-proliferative activities of the polyphenolics in the extract.
Das Mühen um die Inventarisierung von Kulturdenkmalen in Deutschland seit Karl Friedrich Schinkel
Creators: name: Wirth, Hermann
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 56 Nr. 1 (2015): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Sonnenfleckenzeichnung Nr. 22837.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.07.1968, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Inhalt
Creators: name: Redaktion, Die
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 56 Nr. 1 (2015): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Electron Thermal Runaway in Atmospheric Electrified Gases: a microscopic approach
Creators: name: Schmalzried Anthony
Publisher: name: Zenodo
Year: 2023
Subjects: Electron
electron-molecule collisions
cross sections database
potential scattering
super-electron
thermal runaway
spectral enhancement
runaway threshold
electric discharge
high electric field
atmospheric gases

description: Thesis elaborated from 2018 to 2023 at the Instituto de Astrofísica de Andalucía under the supervision of Alejandro Luque (Granada, Spain) and Nikolai Lehtinen (Bergen, Norway). This thesis presents a new database of atmospheric electron-molecule collision cross sections which was published separately under the DOI : 

https://doi.org/10.5281/zenodo.8190461

With this new database and a new super-electron management algorithm which significantly enhances high-energy electron statistics at previously unresolved ratios, the thesis explores general facets of the electron thermal runaway process relevant to atmospheric discharges under various conditions of the temperature and gas composition as can be encountered in the wake and formation of discharge channels.
description: Errata:

p.283 eq. (8.32) : factor (2/π) missing (to remain consistent with the convention taken)
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.04.1968, erstellt von Simona Nicolescu, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung Nr. 22751.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.04.1968, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.07.1968, erstellt am Sonnenobservatorium Kanzelhöhe, Kärnten
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage im Sonnenobservatorium Kanzelhöhe in Sattendorf, Österreich. Instrument: Heliostat mit Refraktor Eigenbau (Öffnung 110mm, f = 1650mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.05.1968, erstellt am Kandilli Observatorium Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Kandilli Rasathanesi, Çengelköy (Istanbul). Instrument: Refraktor Teleskop (Öffnung 200 mm, f = 3070 mm, projiziertes Sonnenbild D = 25 cm).
Instrumentennachweis gemäss Kandilli Observatory Istanbul, Report from Solar Institute, in: Solar Physics, 1968, Vol. 3, Issue 3, pp.491-492, DOI: https://doi.org/10.1007/BF00171622
Performance of nonpsychiatric nursing activities reported by psychiatric head nurses in general hospital settings
Creators: name: Kamigaki, Dorothy Masako
Publisher: name: University of Utah
Year: 2012
Subjects: Hospitals
Psychiatric Units

description: The psychiatric head nurse is considered the key to the quality of nursing care given on the psychiatric unit.  She holds a uniquely influential position on the unit had has a decided effect upon the conditions which exist there.  She is directly responsible for the nursing care given on her unit by nursing service personnel.  The increasing complexity of medical practice has necessitated change in nursing care.  These changes have increased the difficulty of coordinating the activities on the unit and have resulted in more responsibilities for the psychiatric head nurse role and add to the confusion and uncertainty which surrounds the functional role of this position.  Studies concerned with the head nurse and the psychiatric head nurse are limited in number and have been done primarily in the eastern United States.  These studies indicated that head nurses were performing many activities which are not on the head nurse level.  There is a difference between what the head nurse should do and what she was actually doing.  This study has been concerned with on aspect of the psychiatric head nurse role.  Two questionnaires were devised to obtain information from psychiatric head nurses in general hospital settings about the non-psychiatric nursing activities they believed they performed.  Non-psychiatric nursing activities were viewed in terms of how many they performed, how many head nurses performed these activities and how much time they devoted to them.  The sample was taken from eight western states
Changes in preferential hydration of glyceraldehyde 3-phosphate dehydrogenase from yeast brought about by coenzyme binding
Creators: name: Sloan, Donald Leroy
Publisher: name: University of Utah
Year: 2012
Subjects: Yeast
Dehydogenases

description: The binding of nicotinamide-adenine dinucleotide to glyceraldehyde 3-phosphate dehydrogenase from yeast was investigated over a temperature and pH range by methods of  fluorescence quenching, sedimentation equilibrium, and nuclear magnetic relaxation in order to characterized aspects of the protein conformational change, and concomitant change is salvation, that are associated with coenzyme binding.  Binding equilibria were measured by the fluorescence quenching method.  The isotherms were sigmoidal in shape at pH 8.5 and hyperbolic at pH 7.4 and 6.5.  The apparent binding constants varied inversely with temperature and stoichiometry was four  binding  sites per molecule to tetrameric enzyme.  Scatchard plots of the data indicated that the dehydrogenase displays positive cooperativity in coenzyme binding at pH 8.5, negative cooperativity in binding at pH 6.5, and that the binding sites were equivalent and independent at pH 7.4.  These results are in accord with and amplify previously published data, obtained under a more restricted range of conditions.  Buoyant densities of the enzyme and its coenzyme complex were measured (a) by analytical equilibrium sedimentation in cesium chloride gradients and (b) by extrapolating the product of sedimentation coefficient and solvent viscosity to zero as a function of solvent density in a series of potassium phosphate solutions.  Formation of the NAD complex in both cases resulted n a increase in buoyant density associated with a significant decrease in preferential hydration, the magnitude of which is a function of temperature and the nature of the salt.  In the buoyant density measurements in cesium chloride, the associated changed in the binding of chloride ions were also measured.  The results of the study are in agreement with independent typed of evidence that NAD addition to the enzyme results in a contraction of the quatemary structure of the protein.  The water proton spin lattice relaxation rate, T1-1 measured at 3.5 MHz in a pulsed nuclear magnetic spectrometer in enhanced in the presence of the dissolved protein.  A further enhancement, following the course of a binding isotherm, occurred on formation of the coenzyme complex.  If the NAD effect were the result of dehydration, there would have been an increase rather than a decrease in the relaxation times.  The observed effect on the water proton T1-1 is thus attributed to a restricted small class of  bound water molecules that lose degrees of freedom as a result of the protein conformational transition.  Such a result is in accord with theory but not previously been observed experimentally.
Sonnenfleckenzeichnung Nr. 22747.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.03.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.04.1968, erstellt vermutlich von Sebestova am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Structural and functional studies of ALIX/AIP1 in HIV-1 budding
Creators: name: Fisher, Robert D.
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Immunodeficiency
subject: Analysis
subject: Physiology
subject: FOS: Biological sciences

description: Budding is an important step in the life-cycle of enveloped viruses such as HIV-1, where viral particles bud through the plasma or endosomal membranes to acquire their lipid envelope. Budding occurs late in the viral life-cycle and is the final step before a virus undergoes proteolytic maturation to produce an infectious virion. Viral budding requires a number of host cellular factors that facilitate the budding process and appear to be important for membrane curvature generation/stabilization or membrane fission events. Two such cellular factors that are involved in budding are TSG101 and ALIX, which are recruited to sites of budding through direct interactions with the viral Gag protein, and function to recruit additional budding machinery. Both TSG101 and ALIX normally function in vesicle budding at the late endosome during multivesicular body (MVB) biogenesis, where cargo molecules such as cell surface receptors are sorted into vesicles of the MVB for subsequent degradation in the lysosome. Both viral and vesicle budding undergo topologically similar events and the current hypothesis is that viruses have usurped cellular machinery normally functioning at the MVB to facilitate viral budding. In order to gain insight into this process, my work in this thesis has focused on structural and functional studies of ALIX with the goal of understanding how ALIX recognizes viruses and recruits additional cellular machinery to sites of budding.  To this end, I have determined the crystal structure of a construct spanning the structured regions of ALIX and shown that the protein is composed of uniquely structured Bro1 and V domains that are providing insight into the mechanism of ALIX's function. Furthermore, I have collaborated to determine the structure of ALIX in complex with the viral peptide recognition sequence as well as the structure of ALIX in complex with CHMP4 proteins, components of the cellular machinery required for viral and vesicle budding. The structural and biochemical characterization of these interactions in this thesis has provided a basis for understanding how ALIX acts as a scaffold to link viral proteins or cellular cargo molecules to the viral and vesicle budding pathways.
Characterization of strength and deformation properties of rock material for design of drilled shafts under lateral load
Creators: name: Timpson, Thomas Cawley
Publisher: name: University of Utah
Year: 2012
Subjects: Laterally loaded drilled shaft
Rock characterization
Strength characterization
Geotechnical engineering

description: One of the most challenging aspects of geotechnical engineering is the characterization of subsurface material. In practice, engineers often base recommendations both directly and indirectly on index properties and corresponding correlations and models. However, these models should be calibrated for site-specific conditions prior to being used as the basis for any substantial design.  This study includes details of a geotechnical case study. The objective of this study was to evaluate existing models used to estimate strength and deformation characteristics of intact rock and rock mass with respect to analyzing laterally loaded drilled shafts. Geological and geotechnical investigations were conducted for the given site. The field investigation employed sampling methods such as rock coring to obtain specimens that could be tested in the laboratory, as well as in-situ pressuremeter testing (PMT). Laboratory tests performed included uniaxial compression, point-load, Brazilian tension, rebound hardness, unit weight, and water content. The subsurface profile was shown to consist of alternating layers of claystone, limestone, and sandstone, overlain by a layer of clayey sand.  To develop a basis for evaluating existing models, the variability associated with strength and index properties was assessed. In addition, site-specific correlations were developed between uniaxial compressive strength (qu) and the various index properties of the intact rock materials. The predictive capability of existing correlations to estimate qu based on index properties was examined. It was found that point-load index (Is(50)) provided the best estimate of qu among the index correlations studied. Additional rock mass correlations were evaluated on the basis of the strength and deformation characteristics derived from the PMT data. It was found that neither rock mass rating (RMR) nor geological strength index (GSI) produced reasonable estimates of rock mass deformation characteristics based on correlations examined.  The method used by the computer program LPILE to develop p-y curves for weak rock (Reese 1997) was evaluated in terms of how well the predicted p-y curves developed compared with those from PMT data. It was found that the weak rock model highly overestimated the stiffness of the rock mass for this particular site compared to stiffness estimated from the PMT results.
Analysis of the SO2-lime reaction system: mathematical modeling and experimental studies with emphasis on stoker applications
Creators: name: Silcox, Geoffrey Damian
Publisher: name: University of Utah
Year: 2012
Subjects: Sulphur dioxide
Limestone
Stokers

description: The growing public concern over the effects of acid rain has resulted in renewed interest in the S02-lime reaction as a means of capturing gaseous SO2 using calcium-based sorbents. In particular, the injection of dry, pulverized limestone directly into coal-fired boilers   is an attractive possibility due to the ease of retrofitting existing boilers and the low cost of limestone. This study examines the application of the pulverized, dry limestone injection process to stoker-fired boilers using a comprehensive mathematical model of the  S02-lime reaction in conjunction with a series of bench-scale experiments. The mathematical model was also used to assess the application of limestone injection for pulverized, coal-fired boilers.  A comparison of model predictions and SO2 capture data obtained as part of this study, and from studies by other researchers, led to the conclusion that the best description of the reaction process was one incorporating an intrinsically zero-order chemical sulfation reaction serially with pore and product layer diffusion steps.  Model predictions showed that sulfur capture increased linearly within creasing Ca/S molar ratio. The predicted apparent dependence on SO2 concentration varied from zero-to-first-order depending on particle size and reaction conditions. For time-temperature histories  typical of boilers, the model demonstrated that the optimum limestone injection location is at the highest temperature at which sulfation is thermodynamically possible (ca. 2250°F at 3000 ppm SO2).  Bench-scale experiments using a pulverized limestone sorbent showed that SO2 capture increased roughly linearly with increasing molar Ca/S ratio. The effects of changes in SO2 partial pressure were small; a six-fold increase in SO2 partial pressure resulted only in a  doubling in capture. The introduction of cooling coils in the bed region of the test facility had no significant impact on SO2 capture.  Capture levels obtained with natural gas doped to 3000 ppm of SO2 at Ca/S=2 ranged from 25 t o 30 percent. With high sulfur Illinois coal at Ca/S = 2 the capture was 35 percent. Comparisons of the model to the data showed good agreement at all conditions.
Inflammatory effects of bacterial endotoxins
Creators: name: Neilsen, Paul O.
Publisher: name: University of Utah
Year: 2012
Subjects: Inflammation
Endotoxins
Bacterial toxins

description: At the dawn of the millennium, bacteria remain a significant threat to human health. Worldwide the toll is enormous, including developed countries like the United States, where there are 500,000 cases of sepsis (a serious disease due to bacterial infection) per year with a mortality rate around 40 percent. It has been appreciated in the last several decades that the human inflammatory response to bacteria causes much of the pathology associated with bacterial diseases. Systemic inflammation may originate in tissues as a small infection with localized inflammation before developing into serious bacterial infections and sepsis. A better understanding of the cellular and molecular details of localized inflammation could potentially lead to better models of bacterial disease, prevent serious disease from developing, and ultimately improved therapies for treating patients. The goal of my thesis research project was to better understand the cells and molecules important for an inflammatory response to bacteria. In this thesis I used isolated human cells to model localized acute inflammation in response to synthetic and purified bacterial endotoxins. I found that bacterial endotoxins modified with an N-terminal triacyl-cystein moiety (bacterial lipoproteins and lipopeptides) activated endothelial cells, neutrophils, monocytes, and platelets. These activities were similar in some ways to cellular activation by the prototypic bacterial endotoxin, lipopolysaccharide, but were also distinct in other important ways. For example, bacterial lipoproteins and lipopeptide activation of endothelial cells and neutrophils were less dependant on serum and serum proteins than was lipopolysaccharide. These differences are important because inflammation generated by lipopolysaccharide has been thought to represent Grain-negative bacterial infections. In addition, I demonstrated that the major lipoprotein purified from E. coli was proinflammatory in a mouse-model of lung inflammation; demonstrating that triacyl-cystein modified bacterial lipoproteins are potent initiators of inflammation both in vitro and in vivo.  My hope is that the work accomplished in this thesis will bring attention to an important class of bacterial endotoxins that have mostly been overlooked. This increased attention will help build models of bacterial infections and syndromes that better mimic human diseases with the ultimate goal of improving therapies and survival for people with bacterial diseases.
Kopie einer Sonnenfleckenzeichnung, unnummeriert.
Chemisch vervielfältigte Kopie der Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.04.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Artificial Intelligence in Education
Creators: name: Thelen, Tobias
name: Abu Ahmad, Raia
name: Artmann, Lisa
name: Angelescu, Erika Monserrat
name: Audichya, Shantanu
name: Breidbach, Kyra
name: Daske, Nele
name: Dettmer, Niklas
name: Duda, Marko
name: Ganning, Eliasz
name: Grafweg, Leonie
name: Gratz, Robin
name: Grauwelman, Isabel
name: Heß, Yannik
name: Heupel, Paula
name: Kock, Fabienne
name: Kohnen, Henriette
name: Korovina, Elena
name: Lazik, Lina
name: Lohkamp, Jakob
name: Lülf, Sönke
name: Malsom Parantean, Febryeric
name: Martynenko, Ilona
name: Meißner, Christian
name: Moriße, Juri
name: Näther, Jacqueline
name: Naujoks, Felix
name: Obeck, Tobi
name: Ohnesorge, Alina
name: Ondreka, Pia Tamina
name: Oprotkowitz, Cosima
name: Palme, Elisa
name: Parra Fernandez, Carlos Alfonso
name: Rau, Michael
name: Rehmer, Mara
name: Rönck, Antonella
name: Sigetova, Kristina
name: Sommer, Anna
name: Trant, Katharina
name: Uhlenbrock, Henriette
name: Vatankhah-Barazandeh, Kamran
name: Witowski, Dennis
name: Witt, Lara-Sophie
name: Wollatz, Frederik
name: Zieba, Liva
name: Zhu, Qirui
name: Titz, Lisa
name: Britt, Niko
name: Dammann, Marlon
name: Niehaus, Nils
name: Vorsteher, Pia
Publisher: name: Universität Osnabrück
Year: 2022
Subjects: subject: Künstliche Intelligenz
subject: Bildung
subject: studentische Arbeiten
subject: Artificial Intelligence
subject: Education
subject: student works
subject: 004 - Informatik
subject: 54.08 - Informatik in Beziehung zu Mensch und Gesellschaft
subject: K.3.1 - Computer Uses in Education

description: This book contains a collection of 19 systematic literature reviews conducted by Cognitive Science students in the "Artificial Intelligence in Education" seminar in the winter term of 2021/2022. From a Cognitive Science and Artificial Intelligence (AI) perspective, the book investigates the state of the art of research on applying AI technology in educational settings as well as the strengths, weaknesses, opportunities, and threats of these applications. The four larger areas covered by the studies are "Didactics and Ethics", "Methods and Technologies", "Extended Reality and Robots", and "Addressing Special Needs".
Sonnenfleckenzeichnung Nr. 22795.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.05.1968, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.05.1968, erstellt am Sonnenobservatorium Kanzelhöhe, Kärnten
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage im Sonnenobservatorium Kanzelhöhe in Sattendorf, Österreich. Instrument: Heliostat mit Refraktor Eigenbau (Öffnung 110mm, f = 1650mm, projiziertes Sonnenbild D = 25cm)
Kopie einer Sonnenfleckenzeichnung, unnummeriert.
Chemisch vervielfältigte Kopie der Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.04.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
In vitro antimicrobial activity of selected essential oils against bacteria and yeasts isolated from the genital tract of mares
Creators: name: Ebani, Valentina Virginia
name: Nardoni, Simona
name: Bertelloni, Fabrizio
name: Pollera, Claudia
name: Pistelli, Luisa
name: Mancianti, Francesca
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: The aim of the present study, the first to test clinical equine isolates, was to evaluate the antimicrobial activity of commercial essential oils (EOs) obtained from Origanum vulgare, Thymus vulgaris, Cinnamomum zeylanicum, Cymbopogon citratus, Aloysia triphylla and Syzygium aromaticum against Streptococcus spp., Staphylococcus spp., Candida albicans and Rhodotorula spp. previously isolated from uteri of mares with reproductive disorders. T. vulgaris showed the best antibacterial activity against all the selected agents, with MICs ranging from 0.07 mg/mL for S. equi subsp. zooepidemicus to 0.29 mg/mL versus Streptococcus sp. and Staphylococcus spp. isolates and versus C. albicans and Rhodotorula spp., with MICs of 0.46 mg/mL and 1.86 mg/mL, respectively. O. vulgare, S. aromaticum, C. zeylanicum EOs showed good antibacterial activity with MICs ranging from 0.07 mg/mL to 0.29 mg/mL, 0.16 mg/mL to 0.32 mg/mL, 0.07 mg/mL to 0.63 mg/mL, respectively; A. triphylla was the most active EO against Rhodotorula spp. (0.43 mg/mL).
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.03.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Barybas Blanchard 1850
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Melolonthidae
Barybas

description: BARYBAS Blanchard, 1850
Barybas Blanchard 1850: 94
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 109, DOI: 10.5281/zenodo.3678492
Kopie einer Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Chemisch vervielfältigte Kopie der Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 08.04.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.05.1968, erstellt am Kandilli Observatorium Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Kandilli Rasathanesi, Çengelköy (Istanbul). Instrument: Refraktor Teleskop (Öffnung 200 mm, f = 3070 mm, projiziertes Sonnenbild D = 25 cm).
Instrumentennachweis gemäss Kandilli Observatory Istanbul, Report from Solar Institute, in: Solar Physics, 1968, Vol. 3, Issue 3, pp.491-492, DOI: https://doi.org/10.1007/BF00171622