cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Antioxidative activities and phenolic compounds of pumpkin (Cucurbita pepo) seeds and amaranth (Amaranthus caudatus) grain extracts
Creators: name: Peiretti, Pier Giorgio
name: Meineri, Giorgia
name: Gai, Francesco
name: Longato, Erica
name: Amarowicz, Ryszard
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Inorganic Chemistry
subject: Plant Biology

description: Phenolic compounds were extracted from pumpkin (Cucurbita pepo) seed and amaranth (Amaranthus caudatus) grain into 80% (v/v) methanol. The extracts obtained were characterised by the contents of total phenolic compounds (TPC), trolox equivalent antioxidant capacity (TEAC), ferric-reducing antioxidant power (FRAP) and antiradical activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH·) radical. The content of individual phenolic compounds was determined by HPLC-DAD method. Pumpkin seeds showed the higher content of TPC than that from amaranth. The TEAC values of both extracts were similar each other. The lower value of FRAP was observed for pumpkin seed. Phenolic compound present in amaranth grain exhibited strongest antiradical properties against DPPH radical. Several peaks were present on the HPLC chromatograms of two extracts. The UV-DAD spectra confirmed the presence of vanillic acid derivatives in the amaranth grain. The three main phenolic compound present in pumpkin seed were characterised by UV-DAD spectra with maximum at 258, 266 and 278 nm.
The contribution of neuroimaging to our understanding of the pathogenesis of child and adolescent psychiatric diseases
Creators: name: Schaer, Marie
Publisher: name: Université de Genève
Year: 2015
Subjects: info:eu-repo/classification/ddc/616.89
Brain development
MRI
Brain imaging
Autism
22q11DS
Velo-cardio-facial syndrome

description: An increasing number of quantitative neuroimaging studies have been published over the last decade, carrying an unprecedented potential to further our understanding of the pathogenesis of mental diseases. MRI can be repeated safely, providing avenues for measuring maturational brain changes. Sophisticated methods also allow exquisite resolution in identifying the locus and nature of alterations. With the growing amount of neuroimaging studies, we are facing the risk to only enumerate all the altered regions, without much advances in understanding the mechanisms at play, and much clinical implications for affected individuals. Here, I emphasize the need to use image processing methods to target specific developmental processes, for a better understanding of the nature and timing of the neurodevelopmental disruption. I also elaborate on the need to understand the heterogeneity in mental diseases, towards the delineation of homogenous subgroups that rely on similar biological pathways, and have comparable prognosis or sensitivity to treatment.
Interplay between the immune response and environmental factors during multiple sclerosis
Creators: name: Pot, Caroline
Publisher: name: Université de Genève
Year: 2016
Subjects: info:eu-repo/classification/ddc/616.07
Multiple sclerosis
Experimental autoimmune encephalomyelitis
Environmental factors
Aryl hydrocarbon receptor
Metallothioneins
Lipid metabolism

description: Multiple sclerosis (MS) is a common neurologic and autoimmune disorder. The development of this disease is under the control of both genetic and environmental factors. Environmental elements such as sun exposure, viral exposition or smoking contribute to MS occurrence. This thesis is based on a compilation of a selection of my publications. We first assessed signaling molecular pathways of CD4+ T cells and could identify elements, which in addition to their link with environment, shape the immune response during experimental autoimmune encephalomyelitis (EAE), an animal model of MS. For examples the aryl hydrocarbon receptor (AhR) controls cytokines secretion and is identified as the receptor of dioxin, a toxin that is potentially lethal; metallothioneins (MTs) negatively regulate Interleukin-10 production but are suited as sensors for heavy metals. I further oriented my research toward immunometabolism and studied the role of the lipid metabolites and T cell migration to the CNS during EAE.
Change in Caco-2 cells following treatment with various lavender essential oils
Creators: name: M. G. Donadu
name: D. Usai
name: V. Mazzarello
name: P. Molicotti
name: S. Cannas
name: M. G. Bellardi
name: S. Zanetti
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Lavender is an aromatic evergreen shrub diffused in the Mediterranean basin appreciated since antiquity. The genus Lavandula is part of Lamiaceae family and includes more than 20 species, among which true lavender (L. vera D.C. or L. angustifolia Miller.) and spike lavender (L. latifolia Medikus); there are also numerous hybrids known as lavandins (L. hybrida Rev.). L. vera, spike lavender and several hybrids are the most intensely used breeding species for the production of essential oils. Lavender and lavandin essential oils have been applied in food, pharmaceutical and other agro industries as biological products. In their chemical composition, terpenes linalool and linalyl acetate along with terpenoids such as 1,8-cineole are mostly responsible for biological and therapeutic activities. This study evaluates cytotoxic activity of essential oils derived from four lavender species on human epithelial colorectal adenocarcinoma cells. Analysis of pre- and post-treatment cell morphology has been performed using scanning electron microscope.
Structure and function of the human genome
Creators: name: Borel, Christelle
Publisher: name: Université de Genève
Year: 2016
Subjects: info:eu-repo/classification/ddc/576.5
Génome ghumain
Régulation génique
ARN non codant

description: Cette thèse présente plusieurs travaux de recherche qui visent à révéler l'architecture du génome humain et les interactions régulant l'expression des gènes. Elle souligne tout particulièrement les travaux innovateurs faits dans le domaine de l'annotation de la partie non codante du génome humain, connue pour générer de nombreuses molécules régulatrices comme les microARNs. Cette thèse aborde également les variations génomiques, observables entre les individus, qui peuvent être à l'origine de maladies à composantes génétiques ou qui prédisposent à l'apparition de maladies complexes dans un contexte environnemental défini. Plusieurs travaux démontrent le lien existant entre les variations génomiques et les variations phénotypiques, essentiellement étudiées au niveau de l'état transcriptionnel des gènes.
State of the Art
Creators: name: Luisa-Maria Kraus
name: Mayr, Melanie
name: Schmid, Mona
Publisher: name: OSF Registries
Year: 2020
Subjects: Green Exercise
IPA
Interpretative Phenomenological Analysis
Meaning in Life Questionnaire
alps
hiking
meaning in life
meaning in life score
mixed-method
mountain hiking
nature
nature connectedness

description: Background Information
Modeling fetal-growth biometry with response modeling methodology (RMM) and comparison to current models
Creators: name: Benson-Karhi, Diamanta
name: Shore, Haim
name: Malamud, Maya
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Monitoring fetal growth via ultrasound requires modeling fetal biometry in terms of gestation age. In this study, we compare Response Modeling Methodology (RMM) to current models, in three stages. First, RMM is used to approximate 47 empirical mean models that have appeared in the literature resulting in models with negligible loss in accuracy (unlike two other commonly applied models). Next, RMM models are fitted to sample averages of the Singaporean population and compared to a formerly published model. A similar simulation-based analysis is performed in the last stage for raw data of the British population. Altogether over 70 comparisons had been performed resulting in RMM consistently delivering better performing models.
Adipose tissue: from obesity to tissue regeneration
Creators: name: Modarressi Ghavami, Seyed Ali
Publisher: name: Université de Genève
Year: 2016
Subjects: info:eu-repo/classification/ddc/617
Adipose tissue
Stem cells
Obesity
Plastic surgery

description: Nowadays, adipose tissue is considered as a mutli-function organ and more recently a source of regenerative cells. Therefore, adipose tissue has gained significant attention. How to reduce it when it is in excess? How to take advantage of it? And even how to increase it when needed? In this thesis, we will demonstrate a) how adipose reduction by plastic surgery can improve quality of life and weight loss, b) how to improve fat grafting outcome by adding platelet-rich plasma (PRP), c) how to have a safer and more effective technique for in vitro adipose-derived stem cells expansion by using autologous PRP instead of actual cell culture media, and e) finally, how to increase soft tissue by an innovative technique composed of microspheres loaded with lipids, which could increase the adipose tissue volume in situ.
A new diacetylated flavonol triglycoside from the aerial parts of Actinidia polygama
Creators: name: Syed, Ahmed Shah
name: Je-Seung Jeon
name: Kim, Chul Young
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: Plant Biology

description: Phytochemical investigation of a methanolic extract of aerial parts Actinidia polygama Miq. led to the isolation of one new diacetylated flavonol triglycoside, kaempferol 3-O-[α-L-rhamnopyranosyl(1→3)-(4-O-acetyl)-O-α-L-rhamnopyranosyl(1→6)-(2-Oacetyl)-O-β-D-galactopyranoside] (1) along with 12 known compounds (2–13). The chemical structures were determined using their spectroscopic data including 1D and 2D NMR. To the best of our knowledge, this is the first time that compounds 2, 4, 6, 7, 8, 9, 12 and 13 are isolated from this plant. All purified compounds were tested for free radical scavenging effect using DPPH and ABTS assays. Our results showed that compounds 4, 6, 7 and 13 have potential antioxidative effect for scavenging both DPPH· and ABTS·+ radicals that are comparable with those of ascorbic acid used as positive control, whereas compounds 1 and 2, which are di- and mono- acetylated flavonol triglycoside respectively, were not found to be potent scavengers of free radicals.
Additional file 3: of TaAAP6-3B, a regulator of grain protein content selected during wheat improvement
Creators: name: Jin, Xiufeng
name: Feng, Bo
name: Xu, Zhibin
name: Fan, Xiaoli
name: liu, Jing
name: Liu, Qin
name: Zhu, Ping
name: Wang, Tao
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Table S1.TaAAP6-3B genotypes and Locus polymorphism in 115 wheat lines. (DOCX 31 kb)
Responsible antibiotic use and control of antimicrobial resistance: a complex challenge
Creators: name: Huttner, Benedikt
Publisher: name: Université de Genève
Year: 2016
Subjects: info:eu-repo/classification/ddc/616
Antibiotic use
Antimicrobial resistance
Antibiotic stewardship
Decolonization
Antibiotic de-escalation
Antibiotic use metrics
Extended spectrum beta-lactamase producing Enterobacteriaceae

description: The introduction of antibiotics to human medicine revolutionized health care like few other innovations. Yet, the benefits conveyed by the availability these safe and effective drugs are threatened by the rapid spread and emergence of antimicrobial resistance (AMR). The epidemiology of AMR is complex and influenced by many different factors. It is, however, clear that antibiotic use in humans is a key driver of AMR. Overall and inappropriate antibiotic use varies widely among settings, for reasons that are incompletely understood. Antibiotic stewardship (ABS) aims to reduce inappropriate antibiotic use, for example through public campaigns in the outpatient setting or dedicated ABS teams in hospitals. ABS faces, however, many challenges such as a lack of a clear consensus of what constitutes inappropriate use and the absence of solid evidence on how best to reduce antibiotic selection pressure. In addition to ABS, other strategies that prevent transmission are needed.
Gaucher disease: Review, epidemiology and modelling of the biological and clinical markers evolution
Creators: name: Stirnemann, Jérôme
Publisher: name: Université de Genève
Year: 2016
Subjects: info:eu-repo/classification/ddc/618.97
Gaucher disease
Lysosomal disorder
Avascular necrosis
Bone infarct
Chitotriosidase
Ferritin
Registry
Mixed models
Frailty model
Joint model
Imiglucerase

description: Gaucher disease (GD) is a rare genetic lysosomal disorder which is sometimes complicated by bone events (BEs) such as avascular necrosis, bone infarct or pathological fracture. It modifies a number of biomarkers (increased chitotriosidase, angiotensin converting enzyme, ferritin and tartrate-resistant acid phosphatase, and decreased platelets levels). Specific treatments are available. In 2009, we established a French Gaucher Disease Registry (FGDR). An epidemiological analysis of all cases of GD in France identified 562 patients, registering 378 with follow-up (including 90 deaths and 46 monoclonal gammopathies) and 283 undergoing follow-up. BE occurred before treatment (130 BE in 67 patients), but also during it (60 BEs in 41 patients), with frequencies at 10 years (95% CI) of 20.3% (14.1%–26.5%) and 19.8% (13.5%–26.1%), respectively after diagnosis and treatment onset. The present work focused particularly on ferritin, showing that other iron-based parameters remained normal (in 72 patients), and it is the first to describe (decreased) glycosylated ferritin in 25 patients with GD. An analysis of 62 patients showed that BEs occurred before and during treatment; biomarkers were modelled (using mixed models) and the impact of slope and values at treatment onset were tested on BEs. In 2009, a worldwide shortage in the supply of imiglucerase led to treatment modifications or interruptions for patients with GD type 1. We describe the shortage's impact on therapeutic management and the disease's course in French patients. We report on the first dynamic model of how biomarkers evolve during the course of GD. This model enabled us to estimate that 95% of biomarkers response to enzyme replacement therapy (ERT) was achieved in 2 years. We also found that by using the current treatment, about 65% of patients should experience a normalisation of chitotriosidase and ferritin. We used a frailty model to analyse the occurrence of repeated BEs in Gaucher patients after treatment initiation. In the discussion, we developed the use of joint models for analysing repeated longitudinal data (biomarkers) and survival time (BEs) in GD. Further studies should continue to use biomarker modelling with the patient registry in order to try to predict BE and other complications before treatment.
Standardized Protocol Items: Recommendations for Observational Studies (SPIROS):
Creators: name: Sijtsma, Klaas
name: Bouter, Lex
name: Kleijnen, Jos
name: Zeegers, Maurice
name: J. André Knottnerus
name: Van Dael, Peter
name: Mahajan, Raman
Publisher: name: OSF Registries
Year: 2018

description: Protocol
INTELLEKTUAL RIVOJLANISHIDA KAMCHILIGI BO'LGAN BOLALARDA SENSOMOTOR FUNKSIYALARNI RIVOJLANISH XUSUSIYATLARI
Creators: name: Tashkenbayeva Dilafruz Baxtiyor qizi Toshkent shahar Shayxontohur tumani Alohida ta'lim ehtiyojlari bo'lgan bolalar uchun ixtisoslashtirilgan 37-maktabning logoped-defektologi.
Publisher: name: Zenodo
Year: 2024

description:         Rivojlanishning hozirgi bosqichida jamiyatimizda alohida ta’limga muhtoj bo‘lgan bolalarning sonini ortib borishi kuzatilmoqda, shuning uchun ko‘plab pedagoglar bugungi kunda intelluktual rivojlanishida kamchiligi bo‘lgan bolalarning rivojlanish muammosini o‘rganishmoqda. Hozirgi kunda psixologiya va pedagogika fanlari inson salomatligidagi barcha funksional og‘ishlar ichida dolzarb bo‘lib, ijtimoiy oqibatlar nuqtai nazaridan intellektual rivojlanishdagi zaiflik eng ko‘p tarqalgan va jiddiy rivojlanish nuqsoni sifatida qaralmoqda.
Appendix to Phonological Exceptionality.pdf
Creators: name: Round, Erich
Publisher: name: figshare
Year: 2017
Subjects: subject: Linguistics
subject: FOS: Languages and literature
subject: 200319 Aboriginal and Torres Strait Islander Languages

description: Appendix to Round, E.R. ‘Phonological exceptionality is localized to phonological elements: the argument from learnability and Yidiny word-final deletion’
Additional file 4: of TaAAP6-3B, a regulator of grain protein content selected during wheat improvement
Creators: name: Jin, Xiufeng
name: Feng, Bo
name: Xu, Zhibin
name: Fan, Xiaoli
name: liu, Jing
name: Liu, Qin
name: Zhu, Ping
name: Wang, Tao
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology
subject: Computational Biology

description: Table S4. Putative cis-regulatory elements detected in TaAAP6-3B-I. (DOCX 15 kb)
Additional file 6: of TaAAP6-3B, a regulator of grain protein content selected during wheat improvement
Creators: name: Jin, Xiufeng
name: Feng, Bo
name: Xu, Zhibin
name: Fan, Xiaoli
name: liu, Jing
name: Liu, Qin
name: Zhu, Ping
name: Wang, Tao
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Table S3. Comparisons the GPC and TKW between TaAAP6-3B-I and TaAAP6-3B-II about 115 lines in five environments. (DOCX 18 kb)
Transferring control demands across incidental learning tasks – stronger sequence usage in serial reaction task after shortcut option in letter string checking
Creators: name: Gaschler, Robert
name: Marewski, Julian N.
name: Wenke, Dorit
name: Frensch, Peter A.
Publisher: name: Humboldt-Universität zu Berlin
Year: 2014
Subjects: subject: incidental learning
subject: information reduction
subject: serial reaction task
subject: transfer
subject: cognitive conflict
subject: instruction following
subject: pliance
subject: 150 Psychologie

description: After incidentally learning about a hidden regularity, participants can either continue to solve the task as instructed or, alternatively, apply a shortcut. Past research suggests that the amount of conflict implied by adopting a shortcut seems to bias the decision for vs. against continuing instruction-coherent task processing. We explored whether this decision might transfer from one incidental learning task to the next. Theories that conceptualize strategy change in incidental learning as a learning-plus-decision phenomenon suggest that high demands to adhere to instruction-coherent task processing in Task 1 will impede shortcut usage in Task 2, whereas low control demands will foster it. We sequentially applied two established incidental learning tasks differing in stimuli, responses and hidden regularity (the alphabet verification task followed by the serial reaction task, SRT). While some participants experienced a complete redundancy in the task material of the alphabet verification task (low demands to adhere to instructions), for others the redundancy was only partial. Thus, shortcut application would have led to errors (high demands to follow instructions). The low control demand condition showed the strongest usage of the fixed and repeating sequence of responses in the SRT. The transfer results are in line with the learning-plus-decision view of strategy change in incidental learning, rather than with resource theories of self-control.
Chemora: A Programming Framework for Physics
Creators: name: Brandt, Steven
Publisher: name: figshare
Year: 2017
Subjects: Applied Computer Science

description: The fundamental difficulty with scientific software is that the existing languages are either too generalpurpose, too low-level, or both. Thus, physics equations are entangled with the way they are implemented and optimized. Because everything is coupled, it is difficult to adapt to algorithm or hardware advances. More importantly, it means that researchers cannot specialize as easily. In principle, it should be possible to independently specify (1) the scientific equations to be solved; (2) the type of grids; (3) the numerical methods, e.g. time integrators, elliptic solvers; (4) the execution platform (desktop, accelerated cluster, etc.); (5) performance goals, e.g. time, power, etc.
Gallup Polling Data 1941-2017: A Century of the American Woman Voter, Release 1.0 REPLICATION
Creators: name: See Survey Notes For Full Citation
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: The files in this archive are intended to be used in conjunction with the main data archive for "A Century of the American Woman Voter", by Cascio and Shenhav, Journal of Economic Perspectives, available at https://doi.org/10.3886/E117331V1 . All do-files are stored in the main data archive. For detailed information about these data (citations to original Gallup polls, background information, etc.), see online appendix to "A Century of the American Woman Voter" available on the JEP website. The files available here for download include the cleaned Stata data sets created from Gallup polling responses. For instructions on how to use these files, see the README at https://doi.org/10.3886/E117331V1
Supplementary information 2: Detailed ddRAD library preparation protocol from RAD sequencing resolves fine-scale population structure in a benthic invertebrate: implications for understanding phenotypic plasticity
Creators: name: Vendrami, David L. J.
name: Telesca, Luca
name: Weigand, Hannah
name: Weiss, Martina
name: Fawcett, Katie
name: Lehman, Katrin
name: M. S. Clark
name: Leese, Florian
name: McMinn, Carrie
name: Moore, Heather
name: Hoffman, Joseph I.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: The field of molecular ecology is transitioning from the use of small panels of classical genetic markers such as microsatellites to much larger panels of single nucleotide polymorphisms (SNPs) generated by approaches like RAD sequencing. However, few empirical studies have directly compared the ability of these methods to resolve population structure. This could have implications for understanding phenotypic plasticity, as many previous studies of natural populations may have lacked the power to detect genetic differences, especially over micro-geographic scales. We therefore compared the ability of microsatellites and RAD sequencing to resolve fine-scale population structure in a commercially important benthic invertebrate by genotyping great scallops (Pecten maximus) from nine populations around Northern Ireland at 13 microsatellites and 10 539 SNPs. The shells were then subjected to morphometric and colour analysis in order to compare patterns of phenotypic and genetic variation. We found that RAD sequencing was superior at resolving population structure, yielding higher Fst values and support for two distinct genetic clusters, whereas only one cluster could be detected in a Bayesian analysis of the microsatellite dataset. Furthermore, appreciable phenotypic variation was observed in size-independent shell shape and coloration, including among localities that could not be distinguished from one another genetically, providing support for the notion that these traits are phenotypically plastic. Taken together, our results suggest that RAD sequencing is a powerful approach for studying both population structure and phenotypic plasticity in natural populations.
Additional file 7: of TaAAP6-3B, a regulator of grain protein content selected during wheat improvement
Creators: name: Jin, Xiufeng
name: Feng, Bo
name: Xu, Zhibin
name: Fan, Xiaoli
name: liu, Jing
name: Liu, Qin
name: Zhu, Ping
name: Wang, Tao
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Table S5. Contents of protein grain from genotypic classes among 197 individuals from a F2 population. (DOCX 15 kb)
Supplementary information 2: Detailed ddRAD library preparation protocol from ddRAD sequencing resolves fine-scale population structure in a benthic invertebrate with implications for understanding phenotypic plasticity
Creators: name: Vendrami, David L. J.
name: Telesca, Luca
name: Weigand, Hannah
name: Weiss, Martina
name: Fawcett, Katie
name: Lehman, Katrin
name: M. S. Clark
name: Leese, Florian
name: McMinn, Carrie
name: Moore, Heather
name: Hoffman, Joseph I.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: The field of molecular ecology is transitioning from the use of small panels of classical genetic markers such as microsatellites to much larger panels of single nucleotide polymorphisms (SNPs) generated by approaches like RAD sequencing. However, few empirical studies have directly compared the ability of these methods to resolve population structure. This could have implications for understanding phenotypic plasticity, as many previous studies of natural populations may have lacked the power to detect genetic differences, especially over micro-geographic scales. We therefore compared the ability of microsatellites and RAD sequencing to resolve fine-scale population structure in a commercially important benthic invertebrate by genotyping great scallops (Pecten maximus) from nine populations around Northern Ireland at 13 microsatellites and 10 539 SNPs. The shells were then subjected to morphometric and colour analysis in order to compare patterns of phenotypic and genetic variation. We found that RAD sequencing was superior at resolving population structure, yielding higher Fst values and support for two distinct genetic clusters, whereas only one cluster could be detected in a Bayesian analysis of the microsatellite dataset. Furthermore, appreciable phenotypic variation was observed in size-independent shell shape and coloration, including among localities that could not be distinguished from one another genetically, providing support for the notion that these traits are phenotypically plastic. Taken together, our results suggest that RAD sequencing is a powerful approach for studying both population structure and phenotypic plasticity in natural populations.
MOESM1 of Extrahepatic cytochrome P450s play an insignificant role in triptolide-induced toxicity
Creators: name: Wei, Yuan
name: Wang, Dujun
name: Chen, Meng
name: Ouyang, Zhen
name: Wang, Shuo
name: Gu, Jun
Publisher: name: figshare
Year: 2018
Subjects: Cell Biology
Molecular Biology
Pharmacology
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 1. Minimum standards of reporting checklist.
MOESM1 of Allogeneic stem-cell transplantation for multiple myeloma: a systematic review and meta-analysis from 2007 to 2017
Creators: name: Yin, Xuejiao
name: Tang, Liang
name: Fan, Fengjuan
name: Jiang, Qinyue
name: Sun, Chunyan
name: Hu, Yu
Publisher: name: figshare
Year: 2018
Subjects: Space Science
Medicine
Biological Sciences not elsewhere classified
Developmental Biology
Cancer
Science Policy
Hematology

description: Additional file 1: Table S1. Characteristics of studies included in the meta-analysis.
RI-VIS D5.1 Communication Standards Toolkit
Creators: name: Costa Abecasis, Rita
name: Pintar, Barbara
Publisher: name: Zenodo
Year: 2020

description: To become sustainable over time, European research infrastructures must increase their visibility, both individually and collectively. This requires the harmonization of the strategies, tools, guidelines and resources that European research infrastructures use in their communication. This toolkit is a collective effort of 31 communication experts representing 17 research infrastructures to provide an easy and useful set of communication tools, guidelines and resources adapted to the needs, constraints and capacities of European research infrastructures. The “Communication Toolkit for European Research Infrastructures” includes: A style guide, comprised of a glossary, a jargon buster and key messages; A website, including guidelines for navigation and the “about us” page, along with contents for a “about EU research infrastructures” webpage A social media strategy and common hashtags Resources, including general PowerPoint slides and strategies to address different targets (private sector, decision-makers and research infrastructures outside of Europe).
MOESM2 of Allogeneic stem-cell transplantation for multiple myeloma: a systematic review and meta-analysis from 2007 to 2017
Creators: name: Yin, Xuejiao
name: Tang, Liang
name: Fan, Fengjuan
name: Jiang, Qinyue
name: Sun, Chunyan
name: Hu, Yu
Publisher: name: figshare
Year: 2018
Subjects: Space Science
Medicine
Pharmacology
Developmental Biology
Cancer
Science Policy
Hematology

description: Additional file 2: Table S2. Patientsâ transplant outcomes of individual clinical trials.
MOESM3 of Allogeneic stem-cell transplantation for multiple myeloma: a systematic review and meta-analysis from 2007 to 2017
Creators: name: Yin, Xuejiao
name: Tang, Liang
name: Fan, Fengjuan
name: Jiang, Qinyue
name: Sun, Chunyan
name: Hu, Yu
Publisher: name: figshare
Year: 2018
Subjects: Space Science
Medicine
Pharmacology
Biological Sciences not elsewhere classified
Developmental Biology
Cancer
Science Policy
Hematology

description: Additional file 3: Table S3. Quality assessment of individual clinical trials.
Additional file 1: of Integration of maternal postpartum services in maternal and child health services in Kaya health district (Burkina Faso): an intervention time trend analysis
Creators: name: YugbarĂŠ Belemsaga, Danielle
name: Goujon, Anne
name: Tougri, Halima
name: Coulibaly, Abou
name: Degomme, Olivier
name: Duysburgh, Els
name: Temmerman, Marleen
name: Kouanda, Seni
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Table S1. Presents data by source and content. (DOCX 12 kb)
MOESM4 of Allogeneic stem-cell transplantation for multiple myeloma: a systematic review and meta-analysis from 2007 to 2017
Creators: name: Yin, Xuejiao
name: Tang, Liang
name: Fan, Fengjuan
name: Jiang, Qinyue
name: Sun, Chunyan
name: Hu, Yu
Publisher: name: figshare
Year: 2018
Subjects: Space Science
Medicine
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Developmental Biology
Science Policy
Hematology

description: Additional file 4: Table S4. Begg and Egger test of studies included in the meta-analysis.
RI-VIS D4.1 Revision of ARIA for RI-VIS
Creators: name: Haley, Natalie
name: Nemytov, Denis
name: Povey, Marcus
name: Smith, Callum
Publisher: name: Zenodo
Year: 2020

description: Access to Research Infrastructure Administration (ARIA) software is already in use across a number of European Research Infrastructures. Through ARIA, a number of community tools are available for research infrastructures, their nodes, projects, facilities and communities. An audit of ARIA functionality was performed to identify the existing functionality which presented opportunities for the RI-VIS project. This audit identified areas where developments of the software could produce new or improved tools and features for addressing RI-VIS stakeholder groups and meeting the needs or the RI-VIS work program. Following this audit, the content management tools were prioritised for development, and an improved content management system was built. The new content management system uniquely integrates data sources from ARIA including news, events and calls in the first instance through application programming interfaces (APIs). The new content management system provides a more intuitive interface for editing content and allows the rapid creation of mobile friendly websites for new and existing communities.
Supplementary information 2 from ddRAD sequencing resolves fine-scale population structure in a benthic invertebrate with implications for understanding phenotypic plasticity
Creators: name: Vendrami, David L. J.
name: Telesca, Luca
name: Weigand, Hannah
name: Weiss, Martina
name: Fawcett, Katie
name: Lehman, Katrin
name: M. S. Clark
name: Leese, Florian
name: McMinn, Carrie
name: Moore, Heather
name: Hoffman, Joseph I.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Detailed ddRAD library preparation protocol.
Supplementary information 3: Computer code and accompanying documentation for morphometrics and colourimetric analyses from RAD sequencing resolves fine-scale population structure in a benthic invertebrate: implications for understanding phenotypic plasticity
Creators: name: Vendrami, David L. J.
name: Telesca, Luca
name: Weigand, Hannah
name: Weiss, Martina
name: Fawcett, Katie
name: Lehman, Katrin
name: M. S. Clark
name: Leese, Florian
name: McMinn, Carrie
name: Moore, Heather
name: Hoffman, Joseph I.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: The field of molecular ecology is transitioning from the use of small panels of classical genetic markers such as microsatellites to much larger panels of single nucleotide polymorphisms (SNPs) generated by approaches like RAD sequencing. However, few empirical studies have directly compared the ability of these methods to resolve population structure. This could have implications for understanding phenotypic plasticity, as many previous studies of natural populations may have lacked the power to detect genetic differences, especially over micro-geographic scales. We therefore compared the ability of microsatellites and RAD sequencing to resolve fine-scale population structure in a commercially important benthic invertebrate by genotyping great scallops (Pecten maximus) from nine populations around Northern Ireland at 13 microsatellites and 10 539 SNPs. The shells were then subjected to morphometric and colour analysis in order to compare patterns of phenotypic and genetic variation. We found that RAD sequencing was superior at resolving population structure, yielding higher Fst values and support for two distinct genetic clusters, whereas only one cluster could be detected in a Bayesian analysis of the microsatellite dataset. Furthermore, appreciable phenotypic variation was observed in size-independent shell shape and coloration, including among localities that could not be distinguished from one another genetically, providing support for the notion that these traits are phenotypically plastic. Taken together, our results suggest that RAD sequencing is a powerful approach for studying both population structure and phenotypic plasticity in natural populations.
On the nexus between growth and disaggregated ecological footprints-empirical evidence from India
Creators: name: Farooq, Umar
name: Paul, Manas
name: Dar, Arif Billah
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: The depletion of natural capital stock due to widespread anthropogenic activities has increased concerns about environmental sustainability. Given this perspective, this study examines the relationship between environmental degradation and economic growth within the framework of the Environmental Kuznets Curve (EKC) hypothesis in India. The growth-environment nexus using Autoregressive Distributive Lag is heterogeneous and footprint-specific. We find an inverted N-shaped EKC for cropland, N-shaped EKC for the forest, grazing, water, and built-up land footprints, and a monotonic increasing relationship for the carbon footprint. Projections based on annual per capita GDP show that cropland depletion would end by 2034 once India’s per capita GDP reaches USD 3,010. Besides, our study predicts that grazing land and forest land footprints will start increasing by 2026 and 2027, corresponding to a per capita GDP of USD 2,208 and USD 2,299. Our finding that the growth-environment relationship is time-varying and heterogeneous suggests policymakers and governments devise footprint-specific strategies to address their depletion.
Additional file 2: of Integration of maternal postpartum services in maternal and child health services in Kaya health district (Burkina Faso): an intervention time trend analysis
Creators: name: Yugbaré Belemsaga, Danielle
name: Goujon, Anne
name: Tougri, Halima
name: Coulibaly, Abou
name: Degomme, Olivier
name: Duysburgh, Els
name: Temmerman, Marleen
name: Kouanda, Seni
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Cell Biology
Biotechnology
Environmental Sciences not elsewhere classified
Developmental Biology
Cancer
Computational Biology

description: Figure S1. Number of lives births per month per place of residence (rural, urban. Figure S1 shows the trend of live births over time in rural and urban HFs. Births follow a seasonal pattern linked to the Sudanese climate zone with dry and rainy seasons. Burkina Faso’s population is mainly rural (> 80%) and during the rainy season, from May to October, people are busy farming. Women become pregnant during the dry season, mainly from December to January, during which farming activities are less intense and temperatures are the lowest (17 °C). Therefore, live birth deliveries were more numerous in September 2013, 2014 and 2015. (DOCX 19 kb)
REVERSIBLE JUMP MARKOV CHAIN MONTE CARLO FOR PULSE FITTING
Creators: name: Goodyer, F
name: Ahmad, BI
name: Godsill, S
Publisher: name: IEEE
Year: 2024
Subjects: 46 Information and Computing Sciences
4603 Computer Vision and Multimedia Computation

description: This paper proposes a reversible jump Markov chain Monte Carlo method that provides efficient inference for the general problem of pulse fitting. In particular, it minimises the potential of an adopted parametric model overfitting to the (noisy) data via the inclusion of a peak proximity parameter. This facilitates learning a more representative underlying model and significantly reduces the computational cost. Synthetic and real data are used to demonstrate the efficacy of the introduced Bayesian technique.
Towards the new generation of quantum sensors – ultracold atoms and NV centres
Creators: name: Craigie, Karen Louise
Publisher: name: The University of St Andrews
Year: 2025
Subjects: Nitrogen-vacancy centre
Bose-Einstein condensate
Quantum sensing
Superposition of persistent currents
BECs in ring traps
Guided atom interferometer
Magnetic field sensing
Bayesian estimation
Tracking a changing magnetic field
Rotation sensing

description: We simulate two different sensing platforms – the nitrogen-vacancy (NV) centre in diamond and Bose-Einstein condensates (BECs) in holographic ring traps – and consider how aspects such as sensitivity and speed can be characterised and optimised. For the case of NV centres, this thesis focuses on their application as high-resolution sensors of magnetic field and investigates optimising the speed of the sensing process as we track a changing magnetic field. Current methods for optimising tracking speed rely on machine learning calculations to reduce the number of measurements required. Our work adds to this speed improvement by reducing the computation time of these calculations via Gaussian approximation. This led to a reduction in computation time by factor 10 in all but the lowest coherence time case, where the more modest improvement in computation time is made up for by an increase in tracking accuracy compared to the original non-approximate method. In terms of the work with BECs, we perform both rotation and magnetic field sensing. To closer predict performance of experimental implementation, we consider the effect of shot noise in the presence of image pixelisation, as a camera would be in a physical set-up. After evaluating sensitivity, we found these to be competitive with state of the art quantum sensing alternatives. Additionally, we explore an innovative approach to engineer the wavefunction of the condensate to create a superposition state.
Spastic hip dysplasia in severe cerebral palsy: Review from the literature
Creators: name: De Coulon, Geraldo
Publisher: name: Université de Genève
Year: 2016
Subjects: info:eu-repo/classification/ddc/618
Hip dysplasia
Cerebral Palsy
Pain
Spasticity

description: Cerebral palsy is a neurodevelopmental condition that could be secondary to hypoxic–ischaemic brain injury during the perinatal period of development or congenital anomalies. Cerebral palsy is the most frequent cause of physical disability in development countries. These patients have motor impairment and also a high rate of mental health problems. Their motor impairments developed unbalanced hip contractures that can lead to silent hip dislocation. The incidence of this complication can be very high, from 15% to 60% (1). There is a relationship with the degree of physical disability and hip dislocation (2). Non-walking patients have a high chance to develop this deformity. The pathogenesis of the progressive hip subluxation from the acetabulum is related to muscular imbalance around the hip. They usually have strong adductors and flexors and unbalanced weak abductors and extensors. The natural history of the hip dislocation can develop pain, contractures and difficulties with hygiene. Surveillance programmes in cerebral palsy patients can help in detecting at-risk patients for hip dislocation, and early recognition enables early appropriate interventions. The surveillance should be performed with regular radiographic hip examination; because physical examination alone is not a reliable method to mesure hip dislocation . Most physicians agree that preventing hip dislocation is a good way to prevent future problems with hip pain and contracture, providing benefits to the family, caregivers and patient (2). Surgical and rehabilitative approaches, such as soft tissue lengthening and proximal femoral and pelvic osteotomies, can help to maintain hip reduce into the acetabulum. The rationale of this review is to evaluate recent literature for current trends in the surveillance and treatment of spastic hip problems in patients with cerebral palsy.
RI-VIS D2.1 Data Set
Creators: name: Battaglia, Serena
name: Fahrner, Sven
Publisher: name: Zenodo
Year: 2020

description: The objectives of this work package are to: ‘map’ the Research Infrastructures (RIs) and their services, and to learn from existing collaboration between European Research Infrastructures and third-country partners as well as with industry partners; to identify gaps in terms of communication; and to determine opportunities for new cooperation and to identify the conditions to develop such cooperation.
Additional file 3: of Integration of maternal postpartum services in maternal and child health services in Kaya health district (Burkina Faso): an intervention time trend analysis
Creators: name: Yugbaré Belemsaga, Danielle
name: Goujon, Anne
name: Tougri, Halima
name: Coulibaly, Abou
name: Degomme, Olivier
name: Duysburgh, Els
name: Temmerman, Marleen
name: Kouanda, Seni
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Astronomical and Space Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Table S2. Monitored indicators by number of cases by health facility per period. Table S2 shows that there was an increase in the number of women who visited day 6–10 and week 6–8 PPC, and who received PPFP counselling and chose an FP method between September 2012 and August 2013 (1st period) and September 2015–December 2015 (2nd period), in both rural and urban areas. For instance in rural HFs, day 6–10 PPC increased from 751 visits in the 1st period to 2733 in the 2nd period, after two years of intervention. (DOCX 15 kb)