cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Microbial Distribution in a Hydrothermal Plume of the Southwestern Indian Ridge
Creators: name: Jiangtao Li
name: Huaiyang Zhou
name: Jiasong Fang
name: Zijun Wu
name: Xiaotong Peng
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Genetics
subject: Microbiology

description: ABSTRACTHydrothermal plumes are widely distributed throughout the global spreading ridges, yet few of them are microbiologically explored. The ultraslow-spreading ridges, recently recognized as a unique, new class of mid-ocean-ridge system, have provided surprises and new insights in hydrothermal system research. A suite of water column samples including both hydrothermal plume samples and ambient seawater were collected at different depths from the ultraslow-spreading Southwest Indian Ridge (SWIR) in 2010. We use molecular approaches such as clone libraries, denaturing gradient gel electrophoresis (DGGE) and quantitative PCR to determine microbial community compositions and their spatial variability within the hydrothermal plume and seawater. Phylogenetic analysis showed that plume samples were mainly dominated by members of α-Proteobacteria and γ-Proteobacteria and members of marine group I group within the Crenarchaeota. Within the hydrothermal plume, archaeal populations were spatially homogeneous, while bacterial compositions were heterogeneous and remarkably distinct at different depths. Moreover, several lineages, closely related to known Mn(II) oxidizers were found to be abundant and even predominant within the plume bacterial communities. DGGE band patterns showed that there was no significant difference in microbial compositions between the samples of hydrothermal plume and ambient seawater. Taken together, we inferred that microbial communities in the SWIR hydrothermal plumes were sourced from ambient seawater rather than from seafloor vent-derived niches. This is the first report on the characteristics of microbial community structures in hydrothermal plume and ambient seawater in the Southwest Indian Ridge.
A role for homologous recombination proteins in cell cycle regulation
Creators: name: Kostyrko, Kaja
name: Bosshard, Sandra
name: Urban, Zuzanna
name: Mermod, Nicolas
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Eukaryotic cells respond to DNA breaks, especially double-stranded breaks (DSBs), by activating the DNA damage response (DDR), which encompasses DNA repair and cell cycle checkpoint signaling. The DNA damage signal is transmitted to the checkpoint machinery by a network of specialized DNA damage-recognizing and signal-transducing molecules. However, recent evidence suggests that DNA repair proteins themselves may also directly contribute to the checkpoint control. Here, we investigated the role of homologous recombination (HR) proteins in normal cell cycle regulation in the absence of exogenous DNA damage. For this purpose, we used Chinese Hamster Ovary (CHO) cells expressing the Fluorescent ubiquitination-based cell cycle indicators (Fucci). Systematic siRNA-mediated knockdown of HR genes in these cells demonstrated that the lack of several of these factors alters cell cycle distribution, albeit differentially. The knock-down of MDC1, Rad51 and Brca1 caused the cells to arrest in the G2 phase, suggesting that they may be required for the G2/M transition. In contrast, inhibition of the other HR factors, including several Rad51 paralogs and Rad50, led to the arrest in the G1/G0 phase. Moreover, reduced expression of Rad51B, Rad51C, CtIP and Rad50 induced entry into a quiescent G0-like phase. In conclusion, the lack of many HR factors may lead to cell cycle checkpoint activation, even in the absence of exogenous DNA damage, indicating that these proteins may play an essential role both in DNA repair and checkpoint signaling.
Optimal Experimental Plan for Multi-level Stress Testing with Weibull Regression under Progressive Type-II Extremal Censoring
Creators: name: Hon Keung Tony Ng
name: İsmail Kınac
name: Coşkun Kuş
name: Chan, Ping Shing
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Computational Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Biotechnology
subject: Medicine

description: In the design of constant-stress life-testing experiments, the optimal allocation in a multi-level stress test with Type-I or Type-II censoring based on the Weibull regression model has been studied in the literature. Conventional Type-I and Type-II censoring schemes restrict our ability to observe extreme failures in the experiment and these extreme failures are important in the estimation of upper quantiles and understanding of the tail behaviors of the lifetime distribution. For this reason, we propose the use of progressive extremal censoring at each stress level, whereas the conventional Type-II censoring is a special case. The proposed experimental scheme allows some extreme failures to be observed. The maximum likelihood estimators of the model parameters, the Fisher information and asymptotic variance-covariance matrices of the maximum likelihood estimates are derived. We consider the optimal experimental planning problem by looking at four different optimality criteria. To avoid the computational burden in searching for the optimal allocation, a simple search procedure is suggested. Optimal allocation of units for 2- and 4-stress-level situations are determined numerically. The asymptotic Fisher information matrix and the asymptotic optimal allocation problem are also studied and the results are compared with optimal allocations with specified sample sizes. Finally, conclusions and some practical recommendations are provided.
Unternehmenssanierung vor Insolvenz - Forderungsverzicht und Rangrücktritt aus zivil-, bilanz-, steuer- und insolvenzrechtlicher Sicht
Creators: name: Hoffmann, Eiko
Publisher: name: Zenodo
Year: 2020
Subjects: Unternehmenskrise, Sanierung, Sanierungsmaßnahmen, Sanierungsinstrumente, Forderungsverzicht, Rangrücktritt

description: In times of crisis, companies also get into economic difficulties. The first part of this publication shows the various stages of a company's crisis and identifies possible reasons for insolvency. It is possible to avert such corporate crises with suitable restructuring instruments. Here, the restructuring measures of debt waiver and subordination are analyzed and examined about the consequences under civil law, accounting law, and tax law.
title: Geodetic Analysis of K-band VLBI Observations Until 2024.0
Creators: name: Krásná, Hana
name: Gordon, David
name: Jacobs, Christopher S.
name: de Witt, Aletha
Publisher: name: TU Wien
Year: 2025
Subjects: VLBI
VLBA
KVN
K-band
EOP

description: https://ivscc.gsfc.nasa.gov/publications/gm2024/NASA-CP-20250002586.pdf -- https://ivscc.gsfc.nasa.gov/publications/gm2024/53_krasna_etal.pdf
description: Multiband delays that are estimated from visibility data using the program fourfit, which is distributed with the Haystack Observatory Postprocessing System (HOPS), do not have a unique ambiguity resolution. At TU Wien, we are looking into options to strengthen the Vienna VLBI and Satellite Software VieVS with an automatic ambiguity resolution module. In the course of these endeavors, we stumbled across the “mbd anchor” keyword of the HOPS fringe fitting program fourfit. This keyword controls how the decision is made as to which of the ambiguous multiband delays is reported. The option, which was introduced for VGOS observations, allows tying the multiband delays to the singleband delays. In order to find out whether we could use this option successfully also for legacy S/X fringe fitting, we performed an initial test. As it turned out, the precision of the S/X singleband delays is not sufficient if the singleband delays lie close to the middle between two multiband delay options.
Comparison of a wipe method with and without a rinse to recover wall losses in closed face 37-mm cassettes used for sampling lead dust particulates
Creators: name: Ceballos, Diana
name: King, Bradley
name: Beaucham, Catherine
name: Brueck, Scott E.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Hematology
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Cell Biology
subject: Engineering

description: Closed-face 37-millimeter (mm) polystyrene cassettes are often used for exposure monitoring of metal particulates. Several methods have been proposed to account for the wall loss in air sampling cassettes, including rinsing, wiping, within-cassette dissolution, and an internal capsule fused to the filter that could be digested with the filter. Until internal capsules replace filters, other methods for assessing wall losses may be considered. To determine if rinsing and wiping or wiping alone is adequate to determine wall losses on cassettes, we collected 54 full-shift area air samples at a battery recycling facility. We collected six replicate samples at three locations within the facility for 3 consecutive days. The wall losses of three replicate cassettes from each day-location were analyzed following a rinse and two consecutive wipes. The wall losses of the other three replicates from each day-location were analyzed following two consecutive wipes only. Mixed-cellulose ester membrane filter, rinse, and wipes were analyzed separately following NIOSH Method 7303. We found an average of 29% (range: 8%–54%) recovered lead from the cassette walls for all samples. We also found that rinsing prior to wiping the interior cassette walls did not substantially improve recovery of wall losses compared to wiping alone. A rinse plus one wipe recovered on average 23% (range: 13%–33%) of the lead, while one wipe alone recovered on average 21% (range: 16%–22%). Similarly we determined that a second wipe did not provide substantial additional recovery of lead (average: 4%, range: 0.4%–19%) compared to the first wipe disregarding the rinse (average: 18%, range: 4%–39%). We concluded that when an internal capsule is not used, wall losses of lead dust in air sampling cassettes can be adequately recovered by wiping the internal wall surfaces of the cassette with a single wipe.
CTCF-dependent co-localization of canonical Smad signaling factors at architectural protein binding sites in D. melanogaster
Creators: name: Bortle, Kevin Van
name: Peterson, Aidan J
name: Takenaka, Naomi
name: O'Connor, Michael B
name: Corces, Victor G
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The transforming growth factor β (TGF-β) and bone morphogenetic protein (BMP) pathways transduce extracellular signals into tissue-specific transcriptional responses. During this process, signaling effector Smad proteins translocate into the nucleus to direct changes in transcription, but how and where they localize to DNA remain important questions. We have mapped Drosophila TGF-β signaling factors Mad, dSmad2, Medea, and Schnurri genome-wide in Kc cells and find that numerous sites for these factors overlap with the architectural protein CTCF. Depletion of CTCF by RNAi results in the disappearance of a subset of Smad sites, suggesting Smad proteins localize to CTCF binding sites in a CTCF-dependent manner. Sensitive Smad binding sites are enriched at low occupancy CTCF peaks within topological domains, rather than at the physical domain boundaries where CTCF may function as an insulator. In response to Decapentaplegic, CTCF binding is not significantly altered, whereas Mad, Medea, and Schnurri are redirected from CTCF to non-CTCF binding sites. These results suggest that CTCF participates in the recruitment of Smad proteins to a subset of genomic sites and in the redistribution of these proteins in response to BMP signaling.
A role for homologous recombination proteins in cell cycle regulation
Creators: name: Kostyrko, Kaja
name: Bosshard, Sandra
name: Urban, Zuzanna
name: Mermod, Nicolas
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: Cancer
subject: Developmental Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: Eukaryotic cells respond to DNA breaks, especially double-stranded breaks (DSBs), by activating the DNA damage response (DDR), which encompasses DNA repair and cell cycle checkpoint signaling. The DNA damage signal is transmitted to the checkpoint machinery by a network of specialized DNA damage-recognizing and signal-transducing molecules. However, recent evidence suggests that DNA repair proteins themselves may also directly contribute to the checkpoint control. Here, we investigated the role of homologous recombination (HR) proteins in normal cell cycle regulation in the absence of exogenous DNA damage. For this purpose, we used Chinese Hamster Ovary (CHO) cells expressing the Fluorescent ubiquitination-based cell cycle indicators (Fucci). Systematic siRNA-mediated knockdown of HR genes in these cells demonstrated that the lack of several of these factors alters cell cycle distribution, albeit differentially. The knock-down of MDC1, Rad51 and Brca1 caused the cells to arrest in the G2 phase, suggesting that they may be required for the G2/M transition. In contrast, inhibition of the other HR factors, including several Rad51 paralogs and Rad50, led to the arrest in the G1/G0 phase. Moreover, reduced expression of Rad51B, Rad51C, CtIP and Rad50 induced entry into a quiescent G0-like phase. In conclusion, the lack of many HR factors may lead to cell cycle checkpoint activation, even in the absence of exogenous DNA damage, indicating that these proteins may play an essential role both in DNA repair and checkpoint signaling.
Multivariate-sign-based high-dimensional tests for the two-sample location problem
Creators: name: Feng, Long
name: Changliang Zou
name: Zhaojun Wang
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences

description: This article concerns tests for the two-sample location problem when data dimension is larger than the sample size. Existing multivariate-sign-based procedures are not robust against high dimensionality, producing tests with type I error rates far away from nominal levels. This is mainly due to the biases from estimating location parameters. We propose a novel test to overcome this issue by using the “leave-one-out” idea. The proposed test statistic is scalar-invariant and thus is particularly useful when different components have different scales in high-dimensional data. Asymptotic properties of the test statistic are studied. Compared with other existing approaches, simulation studies show that the proposed method behaves well in terms of sizes and power.
Comparison of a Wipe Method With and Without a Rinse to Recover Wall Losses in Closed Face 37-mm Cassettes used for Sampling Lead Dust Particulates
Creators: name: Ceballos, Diana
name: King, Bradley
name: Beaucham, Catherine
name: Brueck, Scott E.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Hematology
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Cell Biology
subject: Engineering

description: Closed-face 37-mm polystyrene cassettes are often used for exposure monitoring of metal particulates. Several methods have been proposed to account for the wall loss in air sampling cassettes, including rinsing, wiping, within-cassette dissolution, and an internal capsule fused to the filter that could be digested with the filter. Until internal capsules replace filters, other methods for assessing wall losses may be considered. To determine if rinsing and wiping or wiping alone is adequate to determine wall losses on cassettes, we collected 54 full-shift area air samples at a battery recycling facility. We collected six replicate samples at three locations within the facility for three consecutive days. The wall losses of three replicate cassettes from each day-location were analyzed following a rinse and two consecutive wipes. The wall losses of the other three replicates from each day-location were analyzed following two consecutive wipes only. Mixed-cellulose ester membrane filter, rinse, and wipes were analyzed separately following NIOSH Method 7303. We found an average of 29% (range: 8–54%) recovered lead from the cassette walls for all samples. We also found that rinsing prior to wiping the interior cassette walls did not substantially improve recovery of wall losses compared to wiping alone. A rinse plus one wipe recovered on average 23% (range: 13–33%) of the lead, while one wipe alone recovered on average 21% (range: 16–22%). Similarly, we determined that a second wipe did not provide substantial additional recovery of lead (average: 4%, range: 0.4–19%) compared to the first wipe disregarding the rinse (average: 18%, range: 4–39%). We concluded that when an internal capsule is not used, wall losses of lead dust in air sampling cassettes can be adequately recovered by wiping the internal wall surfaces of the cassette with a single wipe.
CTCF-dependent co-localization of canonical Smad signaling factors at architectural protein binding sites in D. melanogaster
Creators: name: Bortle, Kevin Van
name: Peterson, Aidan J
name: Takenaka, Naomi
name: O'Connor, Michael B
name: Corces, Victor G
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Chemistry
subject: Physics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Hematology
subject: Developmental Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: ABSTRACTThe transforming growth factor beta (TGF-β) and bone morphogenic protein (BMP) pathways transduce extracellular signals into tissue-specific transcriptional responses. During this process, signaling effector Smad proteins translocate into the nucleus to direct changes in transcription, but how and where they localize to DNA remain important questions. We have mapped Drosophila TGF-β signaling factors Mad, dSmad2, Medea, and Schnurri genome-wide in Kc cells and find that numerous sites for these factors overlap with the architectural protein CTCF. Depletion of CTCF by RNAi results in the disappearance of a subset of Smad sites, suggesting Smad proteins localize to CTCF binding sites in a CTCF-dependent manner. Sensitive Smad binding sites are enriched at low occupancy CTCF peaks within topological domains, rather than at the physical domain boundaries where CTCF may function as an insulator. In response to Decapentaplegic, CTCF binding is not significantly altered, whereas Mad, Medea, and Schnurri are redirected from CTCF to non-CTCF binding sites. These results suggest that CTCF participates in the recruitment of Smad proteins to a subset of genomic sites and in the redistribution of these proteins in response to BMP signaling.
Mutant lamin A links prophase to a p53 independent senescence program
Creators: name: Moiseeva, Olga
name: Lessard, Frédéric
name: Acevedo-Aquino, Mariana
name: Vernier, Mathieu
name: Youla S Tsantrizos
name: Ferbeyre, Gerardo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Hematology
subject: Cancer
subject: Developmental Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Microbiology
subject: Biochemistry
subject: Biophysics

description: Expression of oncogenes or short telomeres can trigger an anticancer response known as cellular senescence activating the p53 and RB tumor suppressor pathways. This mechanism is switched off in most tumor cells by mutations in p53 and RB signaling pathways. Surprisingly, p53 disabled tumor cells could be forced into senescence by expression of a mutant allele of the nuclear envelope protein lamin A. The pro-senescence lamin A mutant contains a deletion in the sequence required for processing by the protease ZMPSTE24 leading to accumulation of farnesylated lamin A in the nuclear envelope. In addition, the serine at position 22, a target for CDK1-dependent phosphorylation, was mutated to alanine, preventing CDK1-catalyzed nuclear envelope disassembly. The accumulation of this mutant lamin A compromised prophase to prometaphase transition leading to invaginations of the nuclear lamina, nuclear fragmentation and impaired chromosome condensation. Cells exited this impaired mitosis without cytokinesis and re-replicated their DNA ultimately arresting in interphase as polyploid cells with features of cellular senescence including increased expression of inflammatory gene products and a significant reduction of tumorigenicity in vivo.
CTCF-dependent co-localization of canonical Smad signaling factors at architectural protein binding sites in D. melanogaster
Creators: name: Bortle, Kevin Van
name: Peterson, Aidan J
name: Takenaka, Naomi
name: O'Connor, Michael B
name: Corces, Victor G
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Chemistry
subject: Physics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Hematology
subject: Developmental Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: The transforming growth factor β (TGF-β) and bone morphogenetic protein (BMP) pathways transduce extracellular signals into tissue-specific transcriptional responses. During this process, signaling effector Smad proteins translocate into the nucleus to direct changes in transcription, but how and where they localize to DNA remain important questions. We have mapped Drosophila TGF-β signaling factors Mad, dSmad2, Medea, and Schnurri genome-wide in Kc cells and find that numerous sites for these factors overlap with the architectural protein CTCF. Depletion of CTCF by RNAi results in the disappearance of a subset of Smad sites, suggesting Smad proteins localize to CTCF binding sites in a CTCF-dependent manner. Sensitive Smad binding sites are enriched at low occupancy CTCF peaks within topological domains, rather than at the physical domain boundaries where CTCF may function as an insulator. In response to Decapentaplegic, CTCF binding is not significantly altered, whereas Mad, Medea, and Schnurri are redirected from CTCF to non-CTCF binding sites. These results suggest that CTCF participates in the recruitment of Smad proteins to a subset of genomic sites and in the redistribution of these proteins in response to BMP signaling.
Evaluation of the performance of a rural municipal wastewater treatment plant in Nacogdoches, East Texas (USA)
Creators: name: Kefa K. Onchoke
name: Janusa, Michael A.
name: Salomey Asantewaa Sasu
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Cell Biology
subject: Microbiology
subject: Engineering
subject: Biochemistry
subject: Biophysics

description: The performance of a rural wastewater treatment facility, Nacogdoches Wastewater Treatment Plant (NWWTP), in East Texas, USA, was assessed from January 2013 through June 2014. The elemental concentrations (Na, Mg, Ca, Ni, Pb, Mn, Cr, Mo, and Cu, Al, As, B, Ba, Ag, Cd, Fe, Hg, K, Se, Zn, Co, P, and S) were measured using inductively coupled plasma optical emission spectrometry. The anion concentrations (Br−, , F−, Cl−, and ) were measured by ion chromatography. In general, the NWWTP was found efficient in removal to ≥ 96% for metals. The removal efficiency for anions was in the range 33–100% (33% for Cl−, 39% for F−, 84% for , and >96% for ). The mean concentrations for Cl−, were in the range 0–172.5, 0.0–0.4, 0.0–18.6, 0.0–98.0, 0.0–0.9, and 4.0–89.4 mg/L, respectively. The concentrations for most metals and anion concentrations, with the exception of phosphates, were found below USEPA maximum contaminant limits.
Antimicrobial activity of the synthesized non-allergenic urushiol derivatives
Creators: name: Jeong-Yong Cho
name: Park, Keun Young
name: Seon-Jae Kim
name: Sejong Oh
name: Jae-Hak Moon
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Molecular Biology
subject: Microbiology
subject: Biochemistry

description: Synthesized urushiol derivatives possessing different carbon atomic length in the alkyl side chain inhibited the growth of food spoilage and pathogenic microorganisms. Particularly, non-allergenic 3-pentylcatechol showed a broad antimicrobial spectrum on an agar plate. Most food spoilage and pathogenic microorganisms were sensitive to urushiol derivatives in the liquid culture. The morphologies of the microorganisms were changed after treatment of 3-pentylcatechol.
title: The Q-band (43 GHz) Celestial Reference Frame Observed in 2021
Creators: name: Krásná, Hana
name: de Witt, Aletha
name: Jacobs, Christopher S.
name: Gordon, David
name: Jaron, Frédéric
name: Jung, Taehyun
Publisher: name: TU Wien
Year: 2025
Subjects: VLBA
Q-band
CRF

description: https://ivscc.gsfc.nasa.gov/publications/gm2024/index.html -- https://ivscc.gsfc.nasa.gov/publications/gm2024/56_krasna_etal.pdf -- https://ivscc.gsfc.nasa.gov/publications/gm2024/NASA-CP-20250002586.pdf
description: Our Q-band (43 GHz) celestial reference frame, based on three dual-polarization VLBA sessions from 2021, has 428 sources and 67 thousand observations. The primary goal of these sessions was to compare the structure of the active galactic nuclei (AGN) observed at Q-band (43 GHz) to S, X, and K-bands (2.3, 8.4, and 24 GHz) using nearly concurrent VLBA sessions. The solution presented here was made with the VieVS software on February 09, 2024. Median formal precisions are 203 μas in α cos δ and 353 μas in δ . This Q-band frame is based solely on the all northern geometry of the VLBA. As a result, sky coverage is limited to declinations above −45 deg and precision tends to decrease as one moves south. We are exploring the potential to add Q-band VLBI observations using the Korean tri-band (K, Q, W-band) system. In the far south, we are exploring the baseline from Mopra, Australia to the CART 40-m antenna in Argentina. The prospects for future improvements are bright with the aforementioned potential for adding new stations as well as plans for proposing for more Q-band time on the VLBA, and the planned VLBA upgrade from 4 to 8 Gbps data rates.
Yvh1 protein phosphatase is required for pre-autophagosomal structure formation after TORC1 inactivation
Creators: name: Akter MST Yeasmin
name: Talukdar Muhammad Waliullah
name: Kondo, Akihiro
name: Ushimaru, Takashi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: Cancer

description: The pre-autophagosomal structure (PAS) is a putative site for autophagosome formation in budding yeast. Upon nutrient depletion or rapamycin treatment, target of rapamycin complex 1 (TORC1) becomes inactive, inducing PAS formation and autophagy. Here, we show that Yvh1 phosphatase is critical for PAS formation, but not autophagy induction, after TORC1 inactivation.
سایبرنتیک چیست؟
Creators: name: Jamali, Hamid R.
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: استافورد بیر، سایبرنتیک چیست؟ (مترجم همکار سعید اسدی)، تدبیر، جلد ۱۶، شماره ۱۵۵، فروردین ۱۳۸۴، This is Persian translation of the following article: Beer, Stafford (2004), “What is Cybernetics?”, Kybernetes, 33 (3-4), 853-863.
Urban climate and its effect on biochemical and morphological characteristics of Arjun (Terminalia arjuna) plant in National Capital Region Delhi
Creators: name: Gyan Prakash Gupta
name: Bablu Kumar
name: Singh, Sudha
name: U C Kulshrestha
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: Cell Biology

description: This paper reports impacts of urban pollution on the biochemical and morphological characteristics of Arjuna (Terminalia arjuna) in particular the effects of urban industrial dustfall deposition on its foliar surface at a residential site (Jawaharlal Nehru University, JNU) and an industrial site (Sahibabad, SB) in Delhi region. Atmospheric dustfall fluxes were estimated for major anions and cations. Morphological analysis of foliar samples was carried out by using the scanning electron microscope. Biochemical parameters, namely chlorophyll a, chlorophyll b, total chlorophyll, carotenoids, total soluble sugar, proline amino acid and ascorbic acid were also analysed in foliar samples. Results showed that the dustfall fluxes of () at the industrial site were almost three times higher than that of the residential site. This can be attributed to the emissions of industrial activities and diesel-driven vehicular traffic in the area. It was observed that these elevated fluxes of and had significant impacts on the biochemical constituents of the plant and foliar morphology. Concentrations of chlorophyll and carotenoids were recorded decreasing with increasing dustfall fluxes of (), whereas proline and ascorbic acid were found to be increasing with the increase in the dustfall fluxes of () indicating the effect of pollution stress. The study showed that the deposition of dustfall was responsible for damage to stomata and leaf surface morphology, more significantly at the industrial site.
Yvh1 protein phosphatase is required for pre-autophagosomal structure formation after TORC1 inactivation
Creators: name: Akter MST Yeasmin
name: Talukdar Muhammad Waliullah
name: Kondo, Akihiro
name: Ushimaru, Takashi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Microbiology
subject: Biochemistry
subject: Biophysics

description: The pre-autophagosomal structure (PAS) is a putative site for autophagosome formation in budding yeast. Upon nutrient depletion or rapamycin treatment, target of rapamycin complex 1 (TORC1) becomes inactive, inducing PAS formation and autophagy. Here, we show that Yvh1 phosphatase is critical for PAS formation, but not autophagy induction, after TORC1 inactivation.
Mutant lamin A links prophase to a p53 independent senescence program
Creators: name: Moiseeva, Olga
name: Lessard, Frédéric
name: Acevedo-Aquino, Mariana
name: Vernier, Mathieu
name: Youla S Tsantrizos
name: Ferbeyre, Gerardo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Expression of oncogenes or short telomeres can trigger an anticancer response known as cellular senescence activating the p53 and RB tumor suppressor pathways. This mechanism is switched off in most tumor cells by mutations in p53 and RB signaling pathways. Surprisingly, p53 disabled tumor cells could be forced into senescence by expression of a mutant allele of the nuclear envelope protein lamin A. The pro-senescence lamin A mutant contains a deletion in the sequence required for processing by the protease ZMPSTE24 leading to accumulation of farnesylated lamin A in the nuclear envelope. In addition, the serine at position 22, a target for CDK1-dependent phosphorylation, was mutated to alanine, preventing CDK1-catalyzed nuclear envelope disassembly. The accumulation of this mutant lamin A compromised prophase to prometaphase transition leading to invaginations of the nuclear lamina, nuclear fragmentation and impaired chromosome condensation. Cells exited this impaired mitosis without cytokinesis and re-replicated their DNA ultimately arresting in interphase as polyploid cells with features of cellular senescence including increased expression of inflammatory gene products and a significant reduction of tumorigenicity in vivo.
سیاستهای جامعهء اطلاعاتی
Creators: name: Jamali, Hamid R.
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: نیك مور، سیاستهای جامعهء اطلاعاتی، كتابداری و اطلاع‌رسنی، جلد ۲, شماره ۳ (پائیز ۱۳۷۸), ص ۹۱-۱۰۶. This is Persian translation of the following article Moore, Nick (1998), Policies for an Information Society, Aslib Proceedings, 50 (1), 20-24.
سوادرایانه‌ای و اطلاعاتی:چالشهای پیش روی اطلاع‌رسانان مدرن در آستانه قرن بیست و یكم
Creators: name: Jamali, Hamid R.
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: و.سرینی واسولو، سوادرایانه‌ای و اطلاعاتی:چالشهای پیش روی اطلاع‌رسانان مدرن در آستانه قرن بیست و یكم، پیام كتابخانه، سال ۹، شماره ۲، تابستان ۱۳۷۸، ص ۶۲-۶۶. This is Persian translation of the following article: Sreenivasulu, V. (1998), “Computer and Information Literacy: Challenges for the Modern Information Professional at the Advent of the XXI Century”, Online & CD-Rom Review, 22 (6), 395-397.
title: Ambiguity Resolution in Legacy Sessions : The [so far unfulfilled] Promise of mbd_anchor
Creators: name: Nothnagel, Axel
name: Krásná, Hana
name: Bernhart, Simone
Publisher: name: TU Wien
Year: 2025
Subjects: VLBI
VLBI ambiguity

description: https://ivscc.gsfc.nasa.gov/publications/gm2024/NASA-CP-20250002586.pdf -- https://ivscc.gsfc.nasa.gov/publications/gm2024/index.html
description: Multiband delays that are estimated from visibility data using the program fourfit, which is distributed with the Haystack Observatory Postprocessing System (HOPS), do not have a unique ambiguity resolution. At TU Wien, we are looking into options to strengthen the Vienna VLBI and Satellite Software VieVS with an automatic ambiguity resolution module. In the course of these endeavors, we stumbled across the “mbd anchor” keyword of the HOPS fringe fitting program fourfit. This keyword controls how the decision is made as to which of the ambiguous multiband delays is reported. The option, which was introduced for VGOS observations, allows tying the multiband delays to the singleband delays. In order to find out whether we could use this option successfully also for legacy S/X fringe fitting, we performed an initial test. As it turned out, the precision of the S/X singleband delays is not sufficient if the singleband delays lie close to the middle between two multiband delay options.
IL-36 promotes systemic IFN-I responses in severe forms of psoriasis.
Creators: name: Catapano, Marika
name: Vergnano, Marta
name: Romano, Marco
name: Satveer K Mahil
name: Siew-Eng Choon
name: A David Burden
name: Young, Helen S
name: Carr, Ian M
name: Lachmann, Helen J
name: Lombardi, Giovanna
name: Smith, Catherine H
name: Ciccarelli, Francesca D
name: Barker, Jonathan N
name: Capon, Francesca
Publisher: name: The Francis Crick Institute
Year: 2020
Subjects: Genetics & Genomics
Genome Integrity & Repair
Gene Expression
Computational & Systems Biology

description: Psoriasis is an immune-mediated skin disorder associated with severe systemic co-morbidities. While IL-36 is a key disease driver, the pathogenic role of this cytokine has mainly been investigated in skin. Thus, its effects on systemic immunity and extra-cutaneous disease manifestations remain poorly understood. To address this issue, we investigated the consequences of excessive IL-36 activity in circulating immune cells. We initially focused our attention on generalised pustular psoriasis (GPP), a clinical variant associated with pervasive up-regulation of IL-36 signalling. By undertaking blood and neutrophil RNA-sequencing, we demonstrated that affected individuals display a prominent Type-I IFN signature, which correlates with abnormal IL-36 activity. We then validated the association between IL-36 de-regulation and Type-I IFN over-expression in patients with severe psoriasis vulgaris (PsV). We also found that the activation of Type-I IFN genes was associated with extra-cutaneous morbidity, in both GPP and PsV. Finally, we undertook mechanistic experiments, demonstrating that IL-36 acts directly on plasmacytoid dendritic cells (pDCs), where it potentiates Toll-like Receptor (TLR)-9 activation and IFN-α production. This effect was mediated by the up-regulation of PLSCR1, a phospholipid scramblase mediating endosomal TLR-9 translocation. These findings identify an IL-36/Type-I IFN axis contributing to extra-cutaneous inflammation in psoriasis.
Rural teaching: balancing student aspiration and belonging
Creators: name: Walker, Dorothy
Publisher: name: University of Tasmania
Year: 2024

description: The aim of this thesis is to better understand teachers who stay in the place where they were born and how staying has influenced their teaching approaches to balancing a sense of belonging with student aspirations to look beyond their local area. The study investigates the views and practices of six rural teachers and why they stayed to teach in the place where they were born. The issue of teacher recruitment and retention in rural and isolated areas in Tasmania has received considerable attention, however little consideration has been given to teachers who have continued to stay and teach in their place of birth and the implications this has for their teaching practices.
As a rural educator for many years in North-West Tasmania, I have a personal interest in researching this concept and my study provided an opportunity to challenge some common assumptions, such as that remaining in rural places is somehow deficient.
During this study, the unprecedented coronavirus (COVID-19) pandemic provided an unexpected opportunity and perspective to analyse the impact of this event on the teaching practices and beliefs of the participants. This event provided a unique opportunity to extend the research through comparison of pre-pandemic data with post pandemic data on the participants teaching practices.
The narrative inquiry methodology chosen for this study afforded an approach suitable to explore the life stories, beliefs, and teaching practices of long staying teachers and was strongly influenced by constructivist narrative inquirers (e.g., Clandinin & Connelly, 2000; Polkinghorne, 1995). The analysis of the data revealed a profile of individuals who demonstrated through their teaching a strong sense of belonging and connection to community and a valuing of a rural lifestyle and environment. The findings also provided insights into the kind of aspirations the participants believe are important considerations in educating rural students prior to, and during, the 2020 pandemic.
Anti-mycobacterial activity of extracts derived from Australian medicinal plants
Creators: name: Meilak, Michelle
name: Palombo, Enzo
Publisher: name: Swinburne
Year: 2024

description: Extracts of seventeen traditional Australian medicinal plants used to treat infections and respiratory conditions were tested for anti-mycobacterial activity against the fast-growing strains, Mycobacterium fortuitum and M. smegmatis. Four extracts, the aerial parts of Pterocaulon sphacelatum (Asteraceae), the bark and leaves of Acacia ligulata (Mimosaceae), the leaves and stems of Eremophila alternifolia (Myoporaceae) and the leaves of Eremophila longifolia, showed activity against M. smegmatis only, while the two Eremophila extracts were also active against M. fortuitum. The minimum inhibitory concentrations ranged from 20-66 mg mL-1. The identification of the anti-mycobacterial compounds from these extracts may yield new and effective agents to combat diseases caused by Mycobacterium species.
Effect of PTSD treatment on cardiovascular reactivity during trauma memory recall and correspondence with symptom improvement
Creators: name: Carpenter, Joseph K.
name: Pineles, Suzanne L.
name: Griffin, Michael G.
name: Werner, Kimberly
name: Resick, Patricia A.
name: Galovski, Tara E.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Background: Prior research has shown PTSD treatment leads to reductions in cardiovascular reactivity during trauma recall, but the extent to which such reductions are associated with changes in PTSD symptoms is less clear. Moreover, such relationships have not been investigated in a cognitively focused PTSD treatment. Objective: To examine changes in cardiovascular reactivity to the trauma memory in patients receiving cognitive processing therapy (CPT), CPT with a written trauma account, and a written account only condition. We also examined the association of such changes with symptom improvement. Method: 118 women with PTSD secondary to interpersonal violence completed pre- and post-treatment assessments of PTSD symptoms and cardiovascular reactivity during a script-driven imagery task. Results: Results indicated a significant but modest reduction in cardiovascular reactivity in CPT conditions. Changes in cardiovascular reactivity and reexperiencing symptoms were significantly associated among the whole sample. Among individuals with the greatest reactivity to the trauma memory at pretreatment, associations were also seen with changes in total PTSD, numbing, and trauma-related guilt. Conclusions: Results indicate that previous findings on the effect of PTSD treatment on cardiovascular reactivity during trauma recall extend to cognitively oriented treatment. Baseline cardiovascular reactivity may influence the extent to which reductions in PTSD symptoms and reactivity during trauma recall are related. Cognitive Processing Therapy leads to reduced heart rate reactivity when recalling a trauma memory.Decreases in heart rate reactivity are associated with reduced reexperiencing symptoms.Changes in heart rate reactivity and PTSD symptoms are more closely related among patients with greater pretreatment reactivity. Cognitive Processing Therapy leads to reduced heart rate reactivity when recalling a trauma memory. Decreases in heart rate reactivity are associated with reduced reexperiencing symptoms. Changes in heart rate reactivity and PTSD symptoms are more closely related among patients with greater pretreatment reactivity.
Extracts of Eremophila longifolia inhibit the cariogenic activities of streptococcus mutans and streptococcus sobrinus
Creators: name: Hayhoe, E. J.
name: Palombo, Enzo
Publisher: name: Swinburne
Year: 2024

description: Plants belonging to the Eremophila genus are an integral part of the traditional medicine of indigenous Australian populations. Extracts of a number of Eremophilia species have demonstrated the presence of bioactivity, including inhibitory effects against Gram positive bacteria. The aim of the present study was to determine the activity of solvent and aqueous extracts of Eremophilia longifolia stem and leaves against Streptococcus mutans and Streptococcus sobrinus. A stem ethanol extract (SEE) demonstrated growth inhibition of the two cariogenic bacteria with a minimum inhibitory concentration (MIC) of 0.5% (w/v). Time-kill experiments indicated bactericidal activity by SEE within a 2 h period. Furthermore, this study assessed the anticariogenic activity of SEE in terms of its effect on glycolytic pH drop, viability of cells within an artificial biofilm and cell attachment to a membrane. In all experiments, SEE demonstrated significant anticariogenic activity compared with controls (p<0.05, Students t-test). SEE also compared favourably with commercial oral healthcare products. Preliminary phytochemical investigations suggested that the active components within SEE were phenolic compounds but unlikely to be flavonoids. Our study advocates SEE as a worthy candidate for further research into alternative chemotherapeutic approaches to dental caries.
كتابخـانه‌های اسـلامی و تبلیغات فرقـه‌ای
Creators: name: Jamali, Hamid R.
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: روث استلهورن مكنسن، كتابخـانه‌های اسـلامی و تبلیغات فرقـه‌ای; آینـهء پژوهش، سال ۱۲، شماره ۲، خرداد- تیر ۱۳۸۰، ص ۲-۱۹. This is the Persian translation of the following article: MacKensen, Ruth S. (1935, January), “Moslem Libraries and Sectarian Propaganda”, The American Journal of Semitic Languages and Literatures, 51(2), 83-113.
A new triterpenoid saponin and a new natural saponin from the roots of Bupleurum scorzonerifolium willd
Creators: name: Li, Zi-Wei
name: Wu, Jia-Tong
name: Bi, Yu
name: Li, Meng-Meng
name: Naseem, Anam
name: Pan, Juan
name: Guan, Wei
name: Hao, Zhi-Chao
name: Kuang, Hai-Xue
name: Chen, Qing-Shan
name: Zhang, Li-Li
name: Liu, Yan
name: Yang, Bing-You
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences

description: Sixteen triterpenoid saponins were isolated from the roots of Bupleurum scorzonerifolium Willd., including a new triterpenoid saponin and new natural saponin that was characterised by NMR for the first time, along with 14 known triterpenoid saponins. The structures of the compounds were established by 1D and 2D NMR spectroscopy, HR-ESI-MS, and comparison with the literature. The cytotoxic activity of the compounds against 4T1 cells was determined using the CCK8 method. Compounds 9 and 6 showed the strongest cytotoxic activity with IC50 values of 2.75 ± 0.86 and 3.78 ± 0.50 μM, respectively. Compounds 2–5 and 8 showed potent cytotoxic activity. Compounds 14 and 16 showed moderate cytotoxicity.