cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Soluble CD46 as a diagnostic marker of hepatic steatosis
Creators: name: Bitterer, Florian
name: Kupke, Paul
name: Adenugba, Akinbami
name: Evert, Katja
name: Glehr, Gunther
name: Riquelme, Paloma
name: Scheibert, Lena
name: Preverin, Giulia
name: Böhm, Christina
name: Hornung, Matthias
name: Schlitt, Hans J.
name: Wenzel, Jürgen J.
name: Geissler, Edward K.
name: Safinia, Niloufar
name: Hutchinson, James A.
name: Werner, Jens M.
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: Hepatic steatosis; Fatty liver disease; Predictive marker; Innate immunity
subject: 610 Medizin

description: Background
The increasing prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) incurs substantial morbidity, mortality and healthcare costs. Detection and clinical intervention at early stages of disease improves prognosis; however, we are currently limited by a lack of reliable diagnostic tests for population screening and monitoring responses to therapy. To address this unmet need, we investigated human invariant Natural Killer T cell (iNKT) activation by fat-loaded hepatocytes, leading to the discovery that circulating soluble CD46 (sCD46) levels accurately predict hepatic steatosis.
Methods
sCD46 in plasma was measured using a newly developed immuno-competition assay in two independent cohorts: Prospective living liver donors (n = 156; male = 66, female = 90) and patients with liver tumours (n = 91; male = 58, female = 33). sCD46 levels were statistically evaluated as a predictor of hepatic steatosis.
Findings
Interleukin-4-secreting (IL-4+) iNKT cells were over-represented amongst intrahepatic lymphocytes isolated from resected human liver samples. IL-4+ iNKT cells preferentially developed in cocultures with a fat-loaded, hepatocyte-like cell line, HepaRG. This was attributed to induction of matrix metalloproteases (MMP) in fat-loaded HepaRG cells and primary human liver organoids, which led to indiscriminate cleavage of immune receptors. Loss of cell-surface CD46 resulted in unrepressed differentiation of IL-4+ iNKT cells. sCD46 levels were elevated in patients with hepatic steatosis. Discriminatory cut-off values for plasma sCD46 were found that accurately classified patients according to histological steatosis grade.
Interpretation
sCD46 is a reliable clinical marker of hepatic steatosis, which can be conveniently and non-invasively measured in serum and plasma samples, raising the possibility of using sCD46 levels as a diagnostic method for detecting or grading hepatic steatosis.
Generating User Experience Based on Personas with AI Assistants
Creators: name: Huang, Yutan
Publisher: name: arXiv
Year: 2024
Subjects: subject: Software Engineering (cs.SE)
subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Traditional UX development methodologies focus on developing ``one size fits all" solutions and lack the flexibility to cater to diverse user needs. In response, a growing interest has arisen in developing more dynamic UX frameworks. However, existing approaches often cannot personalise user experiences and adapt to user feedback in real-time. Therefore, my research introduces a novel approach of combining Large Language Models and personas, to address these limitations. The research is structured around three areas: (1) a critical review of existing adaptive UX practices and the potential for their automation; (2) an investigation into the role and effectiveness of personas in enhancing UX adaptability; and (3) the proposal of a theoretical framework that leverages LLM capabilities to create more dynamic and responsive UX designs and guidelines.
description: 3 Pages, Accepted at the ICSE2024 Doctoral Symposium
Polytrechna Schuster & Summers 1978
Creators: name: Halliday, R. B.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Diarthrophallidae
Polytrechna

description: Polytrechna Schuster & Summers, 1978
Polytrechna Schuster & Summers, 1978: 339.
Type species Polytrechna serrula Schuster & Summers, 1978: 341, by original designation.
description: Published as part of Halliday, R. B., 2015, Catalogue of genera and their type species in the mite Suborder Uropodina (Acari: Mesostigmata), pp. 101-147 in Zootaxa 3972 (2) on page 126, DOI: 10.11646/zootaxa.3972.2.1, http://zenodo.org/record/232777
Prodinychus Berlese 1917
Creators: name: Halliday, R. B.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Uropodidae
Prodinychus

description: Prodinychus Berlese, 1917
Prodinychus Berlese, 1917: 10.
Type species Dinychus fimicolus Berlese, 1903: 248, by original designation.
description: Published as part of Halliday, R. B., 2015, Catalogue of genera and their type species in the mite Suborder Uropodina (Acari: Mesostigmata), pp. 101-147 in Zootaxa 3972 (2) on page 126, DOI: 10.11646/zootaxa.3972.2.1, http://zenodo.org/record/232777
A Low Temperature Kinetic Study of the C(3P) + CH3OCH3 Reaction. Rate constants, H-atom Product Yields and Astrochemical Implications
Creators: name: Hickson, Kevin M.
name: Loison, Jean-Christophe
name: Wakelam, Valentine
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Atomic carbon in its ground electronic state, C(3P), is expected to be present at high abundances during the evolution of dense molecular clouds. Consequently, its reactions with other interstellar species could have a strong influence on the chemical composition of these regions. Here, we report the results of an investigation of the reaction between C(3P) and dimethylether, CH3OCH3, which was recently detected in dark cloud TMC-1. Experiments were performed to study the kinetics of this reaction using a continuous supersonic flow reactor employing pulsed laser photolysis and pulsed laser induced fluorescence for atomic radical generation and detection respectively. Rate constants for this process were measured between 50 K and 296 K, while additional measurements of the product atomic hydrogen yields were also performed over the 75-296 K range. To better understand the experimental results, statistical rate theory was used to calculate rate constants over the same temperature range and to provide insight on the major product channels. These simulations, based on quantum chemical calculations of the ground triplet state of the C3H6O molecule, allowed us to obtain the most important features of the underlying potential energy surface. The measured rate constant increases as the temperature falls, reaching a value of k_(C+CH_3 OCH_3 )= 7.5 x 10-11 cm3 s-1 at 50 K, while the low measured H-atom yields support the theoretical prediction that the major reaction products are CH3 + CH3 + CO. The effects of this reaction on the abundances of interstellar CH3OCH3 and related species were tested using a gas-grain dense cloud model, employing an expression for the rate constant, k(T) = alpha(T/300)^beta, with alpha = 1.27 x 10-11 and beta = -1.01. These simulations predict that the C(3P) + CH3OCH3 reaction decreases gas-phase CH3OCH3 abundances by more than an order of magnitude at early times.
description: accepted for publication in ACS Earth and Space Chemistry
Fuzzy Q-Learning-Based Opportunistic Communication for MEC-Enhanced Vehicular Crowdsensing
Creators: name: Nguyen, Trung Thanh
name: Nguyen, Truong Thao
name: Nguyen, Thanh Hung
name: Nguyen, Phi Le
Publisher: name: arXiv
Year: 2024
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: This study focuses on MEC-enhanced, vehicle-based crowdsensing systems that rely on devices installed on automobiles. We investigate an opportunistic communication paradigm in which devices can transmit measured data directly to a crowdsensing server over a 4G communication channel or to nearby devices or so-called Road Side Units positioned along the road via Wi-Fi. We tackle a new problem that is how to reduce the cost of 4G while preserving the latency. We propose an offloading strategy that combines a reinforcement learning technique known as Q-learning with Fuzzy logic to accomplish the purpose. Q-learning assists devices in learning to decide the communication channel. Meanwhile, Fuzzy logic is used to optimize the reward function in Q-learning. The experiment results show that our offloading method significantly cuts down around 30-40% of the 4G communication cost while keeping the latency of 99% packets below the required threshold.
description: IEEE Transactions on Network and Service Management
Iphimediidae of New Zealand (Crustacea, Amphipoda)
Creators: name: Coleman, Charles Oliver
name: Lörz, Anne-Nina
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy

description: Key to New Zealand iphimediid species
1 Coxa 5-7 posteriorly bicuspidate .................................. Labriphimedia pulchridentata Stebbing, 1883
- Coxa 5-7 posteriorly smooth or bearing single spine.........................................................................2
2 Four pairs of spines dorsally...............................................................................................................3
- Three pairs of spines dorsally, pleonite 3 not bearing paired spines......................................................4
3 Coxa 1 ventrally acute; urosomite 2 dorsally smooth ..................... Labriphimedia meikae sp. nov.
- Coxa 1 ventrally rounded; urosomite 2 bearing dorsal carina ............................................................... .................................................................................................. Labriphimedia hinemoa (Hurley, 1954)
4 Pleonites 1-2 mid-dorsally smooth prior to paired spines; coxa 7 rounded............................................5
- Pleonites 1-2 with mid-dorsal pointy protrusion prior to paired teeth; coxa with 7 posteroventral margin pointed .................................................................................. Labriphimedia martinae sp. nov.
5 Coxa 1 anterodistally rounded; coxa 6 posteriorly pointed ...................................................................... .......................................................................................... Anisoiphimedia haurakiensis (Hurley, 1954)
- Coxa 1 anterodistally truncate; coxa 6 posteriorly rounded ......... Iphimedia spinosa (Hurley, 1954)
description: Published as part of Coleman, Charles Oliver & Lörz, Anne-Nina, 2013, Iphimediidae of New Zealand (Crustacea, Amphipoda), pp. 1-18 in European Journal of Taxonomy 62 on page 3, DOI: 10.5852/ejt.2013.62, http://zenodo.org/record/3820698
Protodinychus Evans 1957
Creators: name: Halliday, R. B.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Protodinychidae
Protodinychus

description: Protodinychus Evans, 1957
Protodinychus Evans, 1957: 239.
Type species Protodinychus punctatus Evans, 1957: 240, by original designation.
description: Published as part of Halliday, R. B., 2015, Catalogue of genera and their type species in the mite Suborder Uropodina (Acari: Mesostigmata), pp. 101-147 in Zootaxa 3972 (2) on page 126, DOI: 10.11646/zootaxa.3972.2.1, http://zenodo.org/record/232777
Labriphimedia K. H. Barnard 1931
Creators: name: Coleman, Charles Oliver
name: Lörz, Anne-Nina
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Iphimediidae
Labriphimedia

description: Labriphimedia K.H. Barnard, 1931
Labriphimedia K.H. Barnard, 1931: 427 (type species: Labriphimedia vespuccii K.H. Barnard, 1931, original designation).
Maoriphimedia Hurley, 1954: 771 (type species: Maoriphimedia hinemoa Hurley, 1954, original designation). — Karaman & Barnard, 1979: 111 (synonomy).
Type species
Labriphimedia vespucci K.H. Barnard, 1931
Diagnosis
Epistome short and broad. Upper lip wider than long, emarginated or elongate and tapering. Mandible tapering to a smooth spoon-shaped or spatulate apex, molar rudimentary, no spine row. Lower lip without inner lobes. Maxilla 1, palp 2 articles, stout or 1-articulate and minute. Maxilliped outer plate broad, palp slender, 2 nd article not medially produced.
Species composition
Labriphimedia hinemoa (Hurley, 1954)
Labriphimedia martinae sp. nov.
Labriphimedia meikae sp. nov.
Labriphimedia pulchridentata (Stebbing, 1883)
Labriphimedia vespucci K.H. Barnard, 1931
description: Published as part of Coleman, Charles Oliver & Lörz, Anne-Nina, 2013, Iphimediidae of New Zealand (Crustacea, Amphipoda), pp. 1-18 in European Journal of Taxonomy 62 on pages 3-4, DOI: 10.5852/ejt.2013.62, http://zenodo.org/record/3820698
Pseudourodiscella Marais & Loots 1981
Creators: name: Halliday, R. B.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Oplitidae
Pseudourodiscella

description: Pseudourodiscella Marais & Loots, 1981
Pseudourodiscella Marais & Loots, 1981a: 57.
Type species Pseudourodiscella tonopilus Marais & Loots, 1981a: 58, by original designation.
description: Published as part of Halliday, R. B., 2015, Catalogue of genera and their type species in the mite Suborder Uropodina (Acari: Mesostigmata), pp. 101-147 in Zootaxa 3972 (2) on page 127, DOI: 10.11646/zootaxa.3972.2.1, http://zenodo.org/record/232777
Xacara nueva: Digital Edition
Creators: name: Jacsont Pauline
Publisher: name: Zenodo
Year: 2022
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool e-Scriptorium (ALTO-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2024), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Linguistic features of the Gainin dialect
Creators: name: Abdullina Gulfira Rifovna*
name: Alimbayeva Gulshayan Gabsalyamovna
Publisher: name: Zenodo
Year: 2024
Subjects: dialect, dialect, dialecticism, phoneme, phonetic transition, isafet, verb.

description: Abstract: Objective. The article is devoted to the analysis of the peculiarities of the language of the Gaina Bashkirs of the Bardymsky District of the Perm Territory on the basis of the field materials of the expedition organised in the summer of 2023. The novelty of the article lies in the fact that the peculiarities of the language of the Gainin Bashkirs of this region are studied in it from the point of view of the impact of socio-cultural and socio-political changes on them, as well as the identification of their specific features. Materials and methods. The linguistic material collected from the mouths of informants from over thirty localities of the above-mentioned region was subjected to comparative, perceptual, contextual and component analyses. Results. It was established that the language of the Gainin people is very original and differs from the dialects of the Bashkir and Tatar languages to a considerable extent by preserving ancient linguistic features, especially phonetic and morphological ones.
DISTENDER_D4.1_Existing climate data
Creators: name: San José, Roberto
name: Pérez Camaño, Juan Luis
name: Ahrens, Bodo
name: Kaur, Manpreet
name: Monjo, Robert
name: Prado, Carlos
name: Redolat, Darío
name: Paradinas, César
Publisher: name: Zenodo
Year: 2024

description: This deliverable describes the climate data used by climate modelling partners to produce local climate scenarios for the DISTENDER core case studies (CCS). The local climate data will be used to drive WP5 impact models and to produce climate indicators for the T5.7 Risk and vulnerability assessment. For each of the four global climate scenarios, projections will be calculated using statistical and dynamical downscaling techniques. This deliverable is the outcome of the T4.1 “Acquisition and analysis of existing simulations and observations” with the objective: “Collect and store the data required by the models and tools of the WPs and which are not the responsibility of the case studies (defined in task T9.2.1), e.g., outputs of the global climate models. Data will be analysed to better understanding and managing climate risks in climate-sensitive sectors”.The four global climate scenarios that have been selected in DISTENDER are the corresponding Tier 1 CMIP6 scenarios: SSP126, SSP245, SSP370, SSP585. Outputs from global climate models for these four scenarios are available through the CMIP6 search interface under the auspices of the World Climate Research Programme (WCRP). Daily and monthly global climate projections data from CMIP6 are available through Copernicus Climate Data Store (CDS) which is the main user interface of the Copernicus Climate Change Service (C3S) implemented by ECMWF on behalf of the EU. Due to the large size of these dataset, the global climate data will not be uploaded in the DISTENDER SFTP. These data will be available locally and can be uploaded into the SFTP as specific request from other partners.Simulations have been generated by multiple independent climate research centres in an effort coordinated by the WCRP and assessed by the Intergovernmental Panel on Climate Change (IPCC). These climate projections underpin the conclusions of the IPCC Assessment Reports that “Continued emission of greenhouse gases will cause further warming and long-lasting changes in all components of the climate system, increasing the likelihood of severe, pervasive and irreversible impacts for people and ecosystems”.
Cold-induced phosphatidylethanolamine synthesis in liver and brown adipose tissue of mice
Creators: name: Hidrobo, Maria Soledad
name: Höring, Marcus
name: Brunner, Sarah
name: Liebisch, Gerhard
name: Schweizer, Sabine
name: Klingenspor, Martin
name: Schreiber, Renate
name: Zechner, Rudolf
name: Burkhardt, Ralph
name: Ecker, Josef
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: Cold exposure, Lipidomics, Lipolysis, Liver lipidome, Phosphatidylethanolamine, PUFA
subject: 610 Medizin

description: Increasing energy expenditure in brown adipose (BAT) tissue by cold-induced lipolysis is discussed as a potential strategy to counteract imbalanced lipid homeostasis caused through unhealthy lifestyle and cardiometabolic disease. Yet, it is largely unclear how liberated fatty acids (FA) are metabolized. We investigated the liver and BAT lipidome of mice housed for 1 week at thermoneutrality, 23 °C and 4 °C using quantitative mass spectrometry-based lipidomics. Housing at temperatures below thermoneutrality triggered the generation of phosphatidylethanolamine (PE) in both tissues. Particularly, the concentrations of PE containing polyunsaturated fatty acids (PUFA) in their acyl chains like PE 18:0_20:4 were increased at cold. Investigation of the plasma's FA profile using gas chromatography coupled to mass spectrometry revealed a negative correlation of PUFA with unsaturated PE in liver and BAT indicating a flux of FA from the circulation into these tissues. Beta-adrenergic stimulation elevated intracellular levels of PE 38:4 and PE 40:6 in beige wildtype adipocytes, but not in adipose triglyceride lipase (ATGL)-deficient cells. These results imply an induction of PE synthesis in liver, BAT and thermogenic adipocytes after activation of the beta-adrenergic signaling cascade.
Pseuduropoda Oudemans 1936
Creators: name: Halliday, R. B.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Trematuridae
Pseuduropoda

description: Pseuduropoda Oudemans, 1936
Pseuduropoda Oudemans, 1936: 407.
Type species Notaspis obscurus Koch, 1835: 5, by monotypy. (= Acarus vegetans De Geer, 1768)
Notes. T he genus name Notaspis Koch, 1835 is a junior homonym of Notaspis Hermann, 1804, and was replaced by Pseuduropoda Oudemans, 1936. The type species of Notaspis Koch, 1835 is Notaspis obscurus Koch, 1835 by monotypy; this is therefore also the type species of Pseuduropoda Oudemans, 1936. However, Oudemans (1936) stated that the type species of Pseuduropoda is Acarus vegetans De Geer, 1768. Notaspis obscurus Koch, 1835 is a junior subjective synonym of Acarus vegetans De Geer, 1768 (not Acarus vegetans Latreille, 1806). Acarus vegetans De Geer, 1768 is also a subjective synonym of Notaspis marginatus Koch, 1839 (see for example, Farrier & Hennessey, 1993). Notaspis marginatus Koch, 1839 is the type species of Fuscuropoda Vitzthum, 1924. Pseuduropoda therefore becomes a subjective synonym of Fuscuropoda. The genus name has been incorrectly spelled as Pseudouropoda by some authors. Some sources refer to a genus name Pseuduropoda Berlese, 1888, but no such name exists.
description: Published as part of Halliday, R. B., 2015, Catalogue of genera and their type species in the mite Suborder Uropodina (Acari: Mesostigmata), pp. 101-147 in Zootaxa 3972 (2) on page 127, DOI: 10.11646/zootaxa.3972.2.1, http://zenodo.org/record/232777
Xacara nueva: Digital Edition
Creators: name: Jacsont Pauline
Publisher: name: Zenodo
Year: 2024
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool eScriptorium (ALTO-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2024), led by professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Factors influencing adoption and intensity of agroforestry systems for mitigating land degradation (MLD) in Gilgel Gibe I catchment, southwestern Ethiopia
Creators: name: Bekele, Endale
name: Abera, Girma
name: Temesgen, Habtamu
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: While agroforestry systems serve as alternative land management strategies aimed at enhancing soil properties and augmenting carbon storage, their adoption and implementation intensity remain limited in Ethiopia. This study designed to identify factors influencing the adoption of agroforestry (AF) for mitigating land degradation (MLD) in the Nadi and Yedi micro watersheds of southwestern Ethiopia, utilizing a reconnaissance field survey and a multi-stage purposive sampling technique. In accordance with this objective, a total of 380 household heads were selected and interviewed using semi-structured questionnaires. Data analysis involved the use of descriptive statistics and the Double Hurdle econometric model. As a result, home gardens (74.4%; 82.8%) and coffee farms (38.6%; 51.5%) were the most widely adopted AF techniques in the Nadi and Yedi watersheds, respectively. More than half of the household heads reported that AF contributes to decreasing soil erosion, enhancing moisture, and improving fertility. The first hurdle model indicates that eight explanatory variables, namely livestock number, farming experience, income, family size, access to information, education level, farm distance, and land security, influenced the adoption of AF practices. In the second hurdle, nine explanatory variables, namely education level, livestock number, income, participation in natural resource projects, access to material support, access to extension, marital status, physical measures conservation, and land security, influenced the adoption intensity of AF practices. This study comprehensively identifies barriers to adopting AF, encompassing institutional, socio-economic, biophysical, and demographic characteristics specific to the study area. As such, future land management initiatives should prioritize a multifaceted approach to accelerate and expand AF adoption, thereby sustainably MLD.
Additional file 9: Figure S4. of Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae
Creators: name: Kyriakou, Dimitris
name: Stavrou, Emmanouil
name: Demosthenous, Panayiota
name: Angelidou, Georgia
name: Bryan-Joseph San Luis
name: Boone, Charles
name: Promponas, Vasilis
name: Kirmizis, Antonis
Publisher: name: Figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Developmental Biology
subject: Cancer

description: Lack of SUT457 accelerates senescence in tlc1Δ cells. a, b Senescence assays performed using liquid cultures of the indicated isogenic wild-type and mutant strains. The strains were generated through tetrad dissection of the heterozygous diploid double mutant SUT457/sut457ΔTLC1/tlc1Δ. Each plot represents one of three independent tetrads examined (see also Fig. 3e). (PDF 65 kb)
A thesis of clinical research: Part A: A systematic review of intervention components utilised in CBT-informed self-help interventions for psychosis; Part B: A thematic analysis of the barriers and facilitators faced by individuals when utilising a guided self-help intervention for distressing voices; Part C: Summary of clinical practice and assessments
Creators: name: Tomlin, Paul
Publisher: name: University of Surrey
Year: 2024
Subjects: Psychosis
Schizophrenia
Self-Help Projects

description: Waiting times for evidence-based psychological therapies is a source of concern for healthcare systems globally. Alternatives to traditional face-to-face talking therapies are needed. Self-help interventions can be used independently of contact with a healthcare professional, and offer a degree of flexibility and discretion that can better suit the needs of some individuals. Self-help interventions are widely used for common mental health difficulties, but the application of these approaches to severe mental health difficulties like psychosis is under-researched.This thesis aims to build in this area. Part A is a systematic review of CBT-informed guided and unguided self-help interventions that have been tested with people with psychosis, and what components make up the interventions. Findings of this study suggest relatively few interventions have been made, with most in the feasibility stages and largely heterogeneous from one another despite all utilising a CBT approach. This study argues that greater consistency of approach, and a focus on factors that improve engagement, would help the literature more out of its nascent stage into a more coherent body of evidence.Part B focusses on engagement with self-help as experienced by people who experience distressing auditory verbal hallucinations, an experience commonly associated with psychosis. Participants from an ongoing NHS research trial of a guided self-help intervention for distressing auditory verbal hallucinations were interviewed as to what factors made it easier, or harder, for them to make use of the intervention. Reflexive Thematic Analysis of the interviews suggested that personal resources and capacity to engage with self-help, the perceived credibility and accessibility of the self-help intervention itself, and relationship with the guides all appeared to modulate engagement. Part B concludes with suggestions as to how self-help could be made easier to engage with for people who experience auditory verbal hallucinations, which may inform design and implementation of self-help for this population.
Rotundabaloghia Hirschmann 1975
Creators: name: Halliday, R. B.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Uropodidae
Rotundabaloghia

description: Rotundabaloghia Hirschmann, 1975
Rotundabaloghia Hirschmann, 1975a: 23.
Type species Rotundabaloghia baloghi Hirschmann, 1975b: 28; 1975c: 29, by original designation.
Notes. The descriptions of the genus Rotundabaloghia and its type species were published in two different papers, with the genus described before its type species. However, since these papers were bound together and published simultaneously, I consider both to be validly published and available.
description: Published as part of Halliday, R. B., 2015, Catalogue of genera and their type species in the mite Suborder Uropodina (Acari: Mesostigmata), pp. 101-147 in Zootaxa 3972 (2) on page 127, DOI: 10.11646/zootaxa.3972.2.1, http://zenodo.org/record/232777
title: Geological Record of Water and Wind Processes on Mars as Observed by the Mars Express High Resolution Stereo Camera
Creators: name: Jaumann, Ralf
name: Tirsch, D.
name: Adeli, Solmaz
name: Bahia, Rickbir
name: Michael, Gregory
name: Le Deit, L.
name: Grau Galofre, A.
name: Head, J.
name: Bohacek, E.
name: Gross, Christoph
name: Walter, Sebastian H. G.
name: Hiesinger, H.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Mars Express
subject: Surface processes
subject: Water
subject: Wind
subject: Climate
classificationCode: 520
subject: Astronomie und zugeordnete Wissenschaften

description: This review paper summarizes the observations and results of the Mars Express Mission and its application in the analysis of geological processes and landforms on Mars during the last 20 years. The Mars Express observations provided an extended data base allowing a comparative evaluation of different geological surface landforms and their time-based delimitation. High-resolution imagery and digital elevations models on a local to regional scale and spectral measurements are the basis for geological analyses of water-related surface processes on Mars. This includes the nature and discharges of valley networks, formation timescale of deltas, volumina of sedimentary deposits as well as estimating the age of geological units by crater size–frequency distribution measurements. Both the quantifying of geological processes and the determination of absolute model ages allows to constraint the evolution of Martian water-related activity in space and time. Comparative age estimation of fluvial, glacial, and lacustrine deposits, as well as their timing and episodicity, has revealed the nature and evolution of the Martian surface hydrological cycle. Fluvial and lacustrine activity phases are spread over a time span from Noachian until Amazonian periods, but detailed studies show that they have been interrupted by multiple and long-lasting phases of cessation and quiescent. In addition, evidence of glacial activity shows discrete phases of enhanced intensity correlating with increased spin-axis obliquity amplitude. The episodicity of geological processes, erosion, deposition, and glaciation on Mars demonstrate a close correlation between individual surface processes and endogenic activity as well as spin-axis/orbital variations and changing climate condition.
Potential of chitosan and silver nanoparticles as fungicides against chocolate spot of faba bean: physiological, ultrastructural and toxicity studies
Creators: name: El-Blasy, Salama S. A.
name: Zian, Ahmed H.
name: El-Gendy, Hala M.
name: Hafez, Mohamed
name: Bourouah, Mohamed
name: Abd-ElGawad, Ahmed M.
name: Rashad, Younes M.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: This study aimed at evaluating the effectiveness of chitosan nanoparticles (ChNPs), silver nanoparticles (AgNPs) and their combination (Ch-AgNPs) in controlling the chocolate spot of faba bean caused by Botrytis fabae. Five isolates of B. fabae were collected from diseased faba bean plants and screened for pathogenicity on the most susceptible faba bean cultivar, Giza 843. Among the isolates, B. fabae isolate No.3 exhibited the highest virulence. Antifungal effects of ChNPs, AgNPs (with an average particle size of 15 and 42 nm, respectively), and Ch-AgNPs mixture at 5, 10 and 20 ppm were assessed against B. fabae isolate No.3. In vitro experiments demonstrated that the Ch-AgNPs mixture at 20 ppm exhibited the greatest inhibitory effect on the mycelial growth of B. fabae, with a reduction of 100% compared to the individual nanoparticles. Transmission electron microscopy revealed notable cellular changes in B. fabae cells treated with the Ch-AgNPs mixture. Greenhouse results exhibited that the great reductions in disease severity were achieved with Tridex 80% WP® fungicide (96.51%), followed by Ch-AgNPs mixture with 84.53% reduction. The Ch-AgNPs mixture effectively enhanced the activity of peroxidase and polyphenoloxidase enzymes and the total phenol content in the plants. Application of ChNPs, AgNPs, and the Ch-AgNPs mixture significantly improved faba bean growth and yield parameters. However, the cytotoxicity assay indicated a concentration-dependent toxic effect of Ch-AgNPs, with no significant hemolytic activity observed in red blood cells. In conclusion, the Ch-AgNPs mixture was promising as a fungicide for combating the chocolate spot in faba bean.
Multi-wavelength observations of the M dwarf flare star binary system EQ Peg
Creators: name: Ní Chonchubhair, Deirdre
Publisher: name: Zenodo
Year: 2024
Subjects: Flare stars
Stellar flares
Optical flares
Multi-wavelength
M dwarf stars

description: EQ Peg is a nearby (6.26 pc) M3.5/M4.5 dwarf flare star binary system with a period of $\sim 180$ years. We present results of a 6.7 hour observation of EQ Peg obtained with the I:IO photometer on the Liverpool Telescope in the SDSS-U passband and compare these with simultaneous radio observations at 4.5-7.5 GHz, part of a campaign involving the eMERLIN and LOFAR radio telescopes to distinguish coronal against stellar magnetospheric emission with U band data used to identify any 'white light' flare events associated with the latter. Of the two components, EQ Peg A was found to be particularly active with a complex pattern of flare events occurring towards the end of the optical observations. These flares had a U' band energy of up to $2.7 \times 10^{31}$ erg. Crosley \& Osten (2018), give a threshold of $8.38 \times 10^{29}$ erg in SDSS U' for a stellar flare to have an accompanying CME, if stellar and solar flares occur at the same flare energy. We see quiescent emission with no flares detected in the eMERLIN data for both EQ Peg A and EQ Peg B. Taken together these data suggest a complex interplay of coronal physical processes resulting in the observed multi-wavelength emission.
Elastography—The New Standard in the Assessment of Fibrosis After Pediatric Liver Transplantation?
Creators: name: Kehler, Thomas
name: Grothues, Dirk
name: Evert, Katja
name: Wahlenmayer, Janka
name: Knoppke, Birgit
name: Melter, Michael
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: elastography | graft fibrosis | liver fibrosis | liver stiffness measurement | pediatric liver transplantation | shear wave elastography
subject: 610 Medizin

description: Background
The development of graft fibrosis after pediatric liver transplantation (PLT) remains a major concern as it can lead to graft failure and ultimately graft loss. Elastography is a non-invasive method to assess liver fibrosis, but its role in the posttransplant setting is unclear. The aim of our study was to evaluate shear wave elastography (SWE) in the assessment of liver fibrosis after PLT, including split-liver recipients.
Methods
We retrospectively analyzed data from PLT recipients who underwent surveillance liver biopsy and concurrent 2D-SWE during the study period from April 2018 to July 2021. Spearman's correlation was used to compare histologic fibrosis stages with liver stiffness measurements (LSM) by 2D-SWE. AUROC analysis was performed to evaluate the performance. One sample t-test was used to compare results with reference values of healthy children.
Results
62 cases were included. 29% showed histologic fibrosis. LSM by 2D-SWE were feasible in all children regardless of age or graft type. There was a significant correlation between LSM and fibrosis stage for all three scoring systems used (Ishak, p = 0.003; METAVIR, p = 0.005; LAF Score, p = 0.003). Patients with a history of biliary complications had increased liver stiffness (p = 0.015). The AUROC of 2D-SWE for predicting significant liver graft fibrosis was 0.81. Liver stiffness after PLT without graft fibrosis was higher than in healthy subjects, but comparable to that in children with chronic liver disease without fibrosis.
Conclusion
2D-SWE can reliably detect children with significant liver graft fibrosis, even in split-liver recipients. This study demonstrates the value of a non-invasive tool for fibrosis staging after PLT. 2D-SWE has the potential to improve long-term outcomes after PLT and to reduce the number of surveillance liver biopsies. But elastography is not a substitute for liver biopsy.
Rotundadinychus Hirschmann 1984
Creators: name: Halliday, R. B.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Dinychidae
Rotundadinychus

description: Rotundadinychus Hirschmann, 1984
Rotundadinychus Hirschmann, 1984c: 132.
Type species Dinychus rotundus Hiramatsu & Hirschmann, 1977: 26, by original designation.
description: Published as part of Halliday, R. B., 2015, Catalogue of genera and their type species in the mite Suborder Uropodina (Acari: Mesostigmata), pp. 101-147 in Zootaxa 3972 (2) on page 127, DOI: 10.11646/zootaxa.3972.2.1, http://zenodo.org/record/232777
Heat stress and it’s tolerance in wheat
Creators: name: Yadav, Sashi Bhusan Kumar
name: Bhatt, Suchi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Plant Biology

description: The rise in world temperature has led to remarkable changes in global climate patterns, eventually devastating the crops. Climate change has led to the emergence of various abiotic factors which has decreased the crop’s productivity. Heat stress has a great role in crop production reduction among various abiotic factors. Rise in temperature at different stages of crop growth beyond threshold level has caused significant crop damage remarkably in wheat. Heat stress causes immense disturbance to the morphological, physiological, and biochemical processes of crops, eventually leading to a decrease in wheat yield. Each degree increase in global temperature has led to a 6% decline in the wheat yield. Heat stress causes a significant decrease in the plant height, photosynthesis rate, dehiscence of the anther, floret fertility, kernel weight, CO2 absorption and assimilation, photosynthesis activity, and chlorophyll content, and starch synthesis in endosperm. Among other stages of the wheat crop, the flowering stage is so prone to heat stress which decreases the seed set. The wheat crop has several tolerance mechanisms to overcome heat stress such as leaf senescence, canopy temperature depression, and heat shock protein. The effect of heat stress is minimized by the production of heat shock protein. Various biochemical and molecular approaches can aid in understanding the effects created by heat stress.
Ruehmnenteria Hirschmann 1979
Creators: name: Halliday, R. B.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Nenteriidae
Ruehmnenteria

description: Ruehmnenteria Hirschmann, 1979
Rühmnenteria Hirschmann, 1979b: 65.
Type species Nenteria ruehmi Hirschmann, 1972f: 18, by original designation (emended from the original spelling rühmi).
Notes. Farrier & Hennessey (1993) incorrectly spelled the genus name as Ruhmnenteria (International Code of Zoological Nomenclature, Article 32.5.2.1).
description: Published as part of Halliday, R. B., 2015, Catalogue of genera and their type species in the mite Suborder Uropodina (Acari: Mesostigmata), pp. 101-147 in Zootaxa 3972 (2) on pages 127-128, DOI: 10.11646/zootaxa.3972.2.1, http://zenodo.org/record/232777
MOESM1 of Targeted quantification of N-1-(carboxymethyl) valine and N-1-(carboxyethyl) valine peptides of Î˛-hemoglobin for better diagnostics in diabetes
Creators: name: Mashanipalya Jagadeeshaprasad
name: Kedar Batkulwar
name: Nishita Meshram
name: Shalbha Tiwari
name: Korwar, Arvind
name: Unnikrishnan, Ambika
name: Kulkarni, Mahesh
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Clinical characteristics of participating subjects.
Sellnickiobovella Hirschmann 1984
Creators: name: Halliday, R. B.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Dinychidae
Sellnickiobovella

description: Sellnickiobovella Hirschmann, 1984
Sellnickiobovella Hirschmann, 1984i: 18.
Type species Fuscuropoda hilli Sellnick, 1970: 253, by original designation.
Notes. Sellnick (1970) spelled the name of the type species as both hilli (six times) and helli (twice). The dedication to Dr Stuart Hill makes it clear that hilli is the correct spelling.
description: Published as part of Halliday, R. B., 2015, Catalogue of genera and their type species in the mite Suborder Uropodina (Acari: Mesostigmata), pp. 101-147 in Zootaxa 3972 (2) on page 128, DOI: 10.11646/zootaxa.3972.2.1, http://zenodo.org/record/232777
Population-based reference values for kidney function and kidney function decline in 25- to 95-year-old Germans without and with diabetes
Creators: name: Herold, Janina M.
name: Wiegrebe, Simon
name: Nano, Jana
name: Jung, Bettina
name: Gorski, Mathias
name: Thorand, Barbara
name: Koenig, Wolfgang
name: Zeller, Tanja
name: Zimmermann, Martina E.
name: Burkhardt, Ralph
name: Banas, Bernhard
name: Küchenhoff, Helmut
name: Stark, Klaus J.
name: Peters, Annette
name: Böger, Carsten A.
name: Heid, Iris M.
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: chronic kidney disease, diabetes, general population, kidney function, kidney function decline, reference values
subject: 610 Medizin

description: Kidney function, assessed as estimated glomerular filtration rate (eGFR), declines by age. In clinical practice, it is important to understand whether a person has an eGFR value as expected given the person’s age, or whether the value is lower than expected and potentially a reason for concern. Although chronic kidney disease is defined as eGFR <60 ml/min per 1.73 m2, the question arises whether a value of, for example, 58 ml/min per 1.73 m2 for an 80-year-old person is indicative of disease or age appropriate. We collected data from >12,000 individuals, aged 25 to 95 years, from population-based German studies. We provide age-specific reference values for eGFR usable in clinical practice to answer this question. Longitudinal information on eGFR decline was analyzed to also provide reference values for eGFR-decline by risk profile groups. Advanced regression models were applied for these analyses. Our results are interpretable and usable to help in clinical routine.
Investigating the potential of Pulicaria jaubertii and Pulicaria petiolaris Herbs as promising functional food ingredients
Creators: name: Al-Maqtari, Qais Ali
name: Mahdi, Amer Ali
name: Othman, Norzila
name: Mohammed, Jalaleldeen Khaleel
name: Al-Ansi, Waleed
name: Noman, Abeer Essam
name: Al-Gheethi, Adel Ali Saeed
name: Asharuddin, Syazwani Mohd
name: Saeed, Adnan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: This study examined the nutritional, phytochemical, and bioactive profiles of Pulicaria jaubertii and Pulicaria petiolaris to establish their suitability as functional food additives. Generally, P. jaubertii exhibited a significantly higher protein and ash content (14.05 and 18.68 g/100 g DW). Conversely, P. petiolaris had higher fat, fiber, and carbohydrate content (3.9, 21.12, and 59.63 g/100 g DW, respectively). In physical investigation, P. jaubertii showed superior bulk density (0.29 g/cm³), tapped density (0.44 g/cm³), hygroscopicity (6.54%), solubility (14.62%), and water absorption capacity (533.42%). Volatile compound analysis found 267 in P. jaubertii, led by carvotanacetone (7.33%), and 371 in P. petiolaris, led by camphor (4.32%). The primary fatty acid constituents in both plants were palmitic and linoleic acids. Mineral analysis indicated P. jaubertii had greater magnesium, potassium, calcium, and iron (139.06, 437.47, 326.96, and 76.73 mg/100g DW, respectively). Leucine and aspartic acid were the most abundant free amino acids in both plants among the 18 essential and non-essential amino acids. Vitamin analyses revealed that P. petiolaris contained a higher B-complex, while ­P. jaubertii had more vitamin C. Interestingly, P. jaubertii exhibited the highest TPC (89.1 mg gallic acid equivalent/g DW), antioxidant activity (6.08 mg ascorbic acid/g DW), and antioxidant capacity (20.71 mg Trolox equivalent/g DW).
Stellar spin-down and Magnetic Activity at the Fully Convective Boundary
Creators: name: Chiti, Federica
Publisher: name: Zenodo
Year: 2024

description: The impact of full convection on stellar dynamos remains an open problem. Recent work has reported an abrupt shift in both rotation and braking torque across the fully convective boundary, suggesting a plausible association with changes in the magnetic field. We examine this transition region with 320 K/M dwarfs within wide (>100 au) binary systems, leveraging the companion white dwarfs’ cooling ages for age determination of these systems. Using a calibrated magnetic braking law, along with assumptions about initial conditions and angular momentum transport, we construct gyrochrones to predict the rotation periods of the main-sequence (MS) stars. Both data and models show that, near the fully convective boundary, MS stars with ages up to 7.5 Gyr experience a rotation period increase by up to a factor of ≈3 within a < 50 K effective temperature range. The rapid braking at this boundary is ubiquitous across models and is driven by a sharp rise in the convective overturn timescale due to structural changes between partially and fully convective stars caused by the 3He instability near the fully convective boundary. Hence, invoking a modification to the stellar dynamo mechanism is not necessary to explain stronger magnetic braking at the fully convective boundary; changes in the torque naturally result from changes in the stellar structure. Stars on this spike show a Rossby number that is 0.2 − 0.7 lower than stars on either side of this feature, depending on the age, corresponding to a ∼ 2 − 20 times enhancement in activity, assuming magnetic activity scales as Ro^(−2). This represents a relatively subtle change compared to the one-order-of-magnitude spread in X-ray luminosities from observational Lx/Lbol−Ro relations, allowing such a feature to escape previous detection.