cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
De l'application des principes de la bonne gouvernance : quand le dire doit correspondre au faire
Creators: name: YEO Zié Seydou
Publisher: name: Zenodo
Year: 2024

description: La bonne gouvernance désigne l’ensemble des mesures, de règles, des organes de décision, d'information et de surveillance qui permettent d'assurer le bon fonctionnement et le contrôle d'un Etat, d'une institution ou d'une organisation qu'elle soit publique ou privée, régionale, nationale ou même internationale. La bonne gouvernance implique de ce fait ainsi une dimension normative ou une dimension d’évaluation au processus de gouvernement. Lorsque l'on s'intéresse alors à sa dimension normative et/ou d’évaluation, il importe de souligner que son efficacité ou son impact réel sur le quotidien des populations dans le processus de développement des Etats ne saurait se limiter à la seule évocation de ses principes entre autres la responsabilité, la transparence, l'Etat de droit, la participation. Une bonne gouvernance exige l'application effective des principes qui la régissent dans le sens où le dire doit être nécessairement un faire comme le stipule la théorie des actes de langage.
Solving Data Integration Problems In Medical Imaging System: A Case Study In Almazov National Medical Research Centre
Creators: name: Radchenko, Irina
name: Chistyakov, Alexander
name: Yarkin, Anton
name: Nikolaev, Igor
name: Lisitsyna, Olga
Publisher: name: Zenodo
Year: 2018
Subjects: PACS
DICOM
HL7

description: Authors present a methodology which allows computer scientists to create and process depersonalised medical data sets. The system being developed allows its users to collect, transform and process data from heterogeneous medical sources and to validate various hypothesis using medical data sets.
Hot articles recently published in the field of pancreatology
Creators: name: ., . .
Publisher: name: JOP. Journal of the Pancreas
Year: 2016
Subjects: Collected Works; Pancreas; Pancreatic Diseases; Pancreatic Neoplasms

description: JOP. Journal of the Pancreas, Vol 1, No 3 (2000): September - p. 46-68
Bombus (Megabombus) consobrinus Dahlbom
Creators: name: An, Jiandong
name: Huang, Jiaxing
name: Shao, Youquan
name: Zhang, Shiwen
name: Wang, Biao
name: Liu, Xinyu
name: Wu, Jie
name: Williams, Paul H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Apidae
Bombus
Bombus consobrinus

description: 17. Bombus (Megabombus) consobrinus Dahlbom
(Figs 36, 37)
Bombus consobrinus Dahlbom, 1832:49.
Material examined. 7 queens, 142 workers, 105 males (IAB).
Distribution in North China. Primarily in the Taihangshan mountains, the Yanshan mountains, and the edge of the east Qinghai-Tibetan plateau. Common at medium elevation of the Baicaopan nature reserve and the Lingshan nature reserve in Beijing, at medium elevation of the Wulingshan nature reserve in Hebei, and at medium to high elevations of the Wutaishan forest park in Shanxi. Rare at medium to high elevations of the Qilianshan nature reserve, the Liancheng nature reserve, the Lianhuashan nature reserve, the Zhagana nature reserve of the east Qinghai-Tibetan plateau in Gansu, the Liupanshan nature reserve of the loess plateau in southern Ningxia, at medium elevations of the Huanggangliang forest park, and at low elevations of the Hulunbeir grasslands in Neimenggu. 53 localities (Fig. 36) between 315–3279 m (IAB).
Similar species in North China. This species is similar in its brown colour pattern with a white tail to B. hypnorum and workers of B. festivus (see the key; Figs 37, 101, 143).
Distribution in China. Beijing, Hebei, Shanxi, Neimenggu, Jilin, Heilongjiang, Gansu, Qinghai, Ningxia, Xinjiang (IAB).
Forage plants. Carduus acanthoides, Cirsium leo, C. setosum, Cosmos bipinnatus, Helianthus annuus, Ixeridium sonchifolium, Saussurea sp.; CRASSULACEAE: Orostachys fimbriata; LAMIACEAE: Dracocephalum heterophyllum, Elsholtzia ciliata, E. fruticosa, E. stauntonii, Leonurus sibiricus, Phlomis umbrosa, Salvia sp.; MALVACEAE: Malva cathayensis; RANUNCULACEAE: Aconitum barbatum, A. kusnezoffii, Clematis tangutica, Trollius chinensis; ROSACEAE: Potentilla chinensis. This species is known in northern Europe to be monolectic (Loken, 1973) but in North China it collects both nectar and pollen from multiple plant species.
description: Published as part of An, Jiandong, Huang, Jiaxing, Shao, Youquan, Zhang, Shiwen, Wang, Biao, Liu, Xinyu, Wu, Jie & Williams, Paul H., 2014, The bumblebees of North China (Apidae, Bombus Latreille), pp. 1-89 in Zootaxa 3830 (1) on pages 32-33, DOI: 10.11646/zootaxa.3830.1.1, http://zenodo.org/record/286560
Additional file 7 of Boring life: early colony formation and growth in the endolithic bryozoan genus Penetrantia Silén, 1946
Creators: name: Decker, Sebastian H.
name: Lemer, Sarah
name: Decker, Simone
name: Hirose, Masato
name: Johnson, Mildred J.
name: Schwaha, Thomas
Publisher: name: figshare
Year: 2024
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Supplementary Material 7
title: Cooling and Manipulation of Atoms in a Microscopic Dipole Trap for Quantum Computing
Creators: name: Patrick, Siobhan
Publisher: name: The Open University
Year: 2024

description: This thesis reports on the development and characterisation of an optical dipole trap for ultracold Rubidium-87 atoms, an important step towards our overall goal of implementing atomic qubits for a protocol known as Deterministic Quantum Computing with One Clean Qubit (DQC1). This protocol has been shown to provide a speed-up over classical algorithms despite having no entanglement present. Since the onset of decoherence is one of the major factors limiting longer algorithms from being performed, we want to investigate this alternative model of quantum computation, where entanglement plays a significantly smaller role. The protocol only requires one pure control qubit, while the ensemble atoms are in the mixed state. We therefore propose to implement DQC1 in the cold atoms platform, which is suited to being scaled up to large qubit numbers, using a scheme where a CNOT gate is performed on the control and ensemble, to create strong quantum correlations between them. The CNOT gate scheme makes use of Rydberg blockade to provide the conditional logic mechanism, and therefore atoms must be well constrained to within the blockade radius of the chosen energy level (Rb = 7.5 µm for the 43D5/2 state), to avoid a breakdown of the blockade and the reduction of the fidelity of the gate. During this PhD an optical dipole trap for this purpose was developed and characterized. Our setup uses a magneto-optical trap to cool the atoms to sub-Doppler temperatures before they are loaded into the dipole trap. Characterisation of the trap is carried out and a trap frequency measurement is performed, which allows the distribution of atoms within the trap to be probed. This measurement
technique has been used in the past for single atoms in dipole traps [1, 2] and on a large ensemble of around 105 atoms [3], but here the method is demonstrated on a mesoscopic cloud for the first time (using 40-50 atoms). A model which simulates the trap frequency measurement for such an ensemble of atoms is also developed and provides useful insight into this novel experiment. Since the results of this experiment indicate that the atoms are insufficiently well localised for high-fidelity implementation of the CNOT gate, initial work on implementing grey molasses cooling, which uses dark states to reduce the warming of atoms due to spontaneous emission recoil, is also presented.
title: Semetey. Heroic epic
Creators: name: ELS IPR BOOKS
Publisher: name: Международный университет Кыргызстана, Turar
Year: 2023

description: Semetey is the second part of the great Kyrgyz epic «Manas». This epic tells about Manas\'s son Semetey how he was brought up after his father\'s death in Buhara. Semetey knew about his real motherland when he was 12 and he came to Talas and became Kyrgyz Khan instead of his father «Manas». It also tells about his marriage to Aichurok and about his battle against the enemies.The main idea is to love motherland and to serve to it.
Additional file 1 of Insights into physical activity promotion among Australian chiropractors: a cross-sectional survey
Creators: name: Fernandez, Matthew
name: de Luca, Katie
name: Moore, Craig
name: French, Simon D.
name: Ferreira, Paulo
name: Swain, Michael
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health

description: Supplementary Material 1
Bombus (Megabombus) koreanus Skorikov
Creators: name: An, Jiandong
name: Huang, Jiaxing
name: Shao, Youquan
name: Zhang, Shiwen
name: Wang, Biao
name: Liu, Xinyu
name: Wu, Jie
name: Williams, Paul H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Apidae
Bombus
Bombus koreanus

description: 18. Bombus (Megabombus) koreanus (Skorikov)
(Figs 38, 39)
Hortobombus koreanus Skorikov, 1933b:59.
Material examined. 4 queens, 85 workers, 10 males (IAB).
Distribution in North China. Primarily in the Yanshan mountains and the Qinling mountains. Common at medium elevations of the Puwa nature reserve and the Lingshan nature reserve in Beijing, the Wulingshan nature reserve in Hebei, the Fuping nature reserve in Shaanxi, and the Xiaolongshan nature reserve in Gansu. Rare at medium elevations of the southern Taihangshan mountains in Shanxi, at the medium elevations on the edge of the Mu Us semi-desert in northern Shaanxi and the loess plateau in central Shaanxi. 32 localities (Fig. 38) between 522–2076 m (IAB).
Similar species in North China. This species is similar in its orange-tailed colour pattern to B. ignitus (see the key; Figs 39, 121).
Distribution in China. Beijing, Hebei, Shanxi, Henan, Shaanxi, Gansu (IAB).
Forage plants. ASTERACEAE: Cosmos bipinnatus; CUCURBITACEAE: Cucumis sativus; FABACEAE: Vicia cracca; BALSAMINACEAE: Impatiens balsamina; LAMIACEAE: Elsholtzia ciliata, Leonurus sibiricus; MALVACEAE: Malva cathayensis; ROSACEAE: Duchesnea indica.
description: Published as part of An, Jiandong, Huang, Jiaxing, Shao, Youquan, Zhang, Shiwen, Wang, Biao, Liu, Xinyu, Wu, Jie & Williams, Paul H., 2014, The bumblebees of North China (Apidae, Bombus Latreille), pp. 1-89 in Zootaxa 3830 (1) on page 33, DOI: 10.11646/zootaxa.3830.1.1, http://zenodo.org/record/286560
Additional file 2 of Insights into physical activity promotion among Australian chiropractors: a cross-sectional survey
Creators: name: Fernandez, Matthew
name: de Luca, Katie
name: Moore, Craig
name: French, Simon D.
name: Ferreira, Paulo
name: Swain, Michael
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health

description: Supplementary Material 2
title: Трудовая миграция из Кыргызстана в Казахстан: причины, последствия и регулирование
Creators: name: ELS IPR BOOKS
Publisher: name: Международный университет Кыргызстана
Year: 2022

description: Монография посвящена международным трудовым миграциям населения из Кыргызской Республики в Республике Казахстан. Исследование охватывает период с конца 1990 по 2020 г., где проведен комплексный анализ о современном состоянии кыргызских внешних трудовых мигрантов в Казахстане, с периодизацией миграционного потока, а также взаимодействие государственных органов и гражданского общества в управлении и регулировании миграционных процессов. Результаты исследования могут быть использованы в планировании эффективной и грамотной миграционной политики в Кыргызской Республике. Монография предназначена для широкого круга читателей: адресуется политологам, социологам, международникам, государственным служащим занимающиеся вопросами миграционной политики, преподавателям вузов, аспирантам и студентам, а также всем, кто интересуется проблемами международной миграции в совремеююм мире.
Additional file 3 of Insights into physical activity promotion among Australian chiropractors: a cross-sectional survey
Creators: name: Fernandez, Matthew
name: de Luca, Katie
name: Moore, Craig
name: French, Simon D.
name: Ferreira, Paulo
name: Swain, Michael
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health

description: Supplementary Material 3
Bombus (Thoracobombus) laesus Morawitz
Creators: name: An, Jiandong
name: Huang, Jiaxing
name: Shao, Youquan
name: Zhang, Shiwen
name: Wang, Biao
name: Liu, Xinyu
name: Wu, Jie
name: Williams, Paul H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Apidae
Bombus
Bombus laesus

description: 19. Bombus (Thoracobombus) laesus Morawitz
(Figs 40, 41)
Bombus laesus Morawitz, 1875:3.
Bombus (Laesobombus) tianschanicus Panfilov, 1956:1327.
Bombus (Laesobombus) maculidorsis Panfilov, 1956:1328, by indication of Skorikov, 1922:23.
Taxonomy. For a discussion of the taxonomy of this species see Williams et al. (2009) and Williams (2011).
Material examined. 29 queens, 171 workers, 24 males (IAB).
Variation in North China. This species or species-complex shows strong variation in the colour pattern of the hair across its global distribution. In North China the principal variation is in the colour of the hair on the dorsum of the thorax, which may be orange-brown or yellow with a black band between the wing bases (see the key).
Similar species in North China. This species is very similar in its orange-brown colour pattern to B. muscorum, B. tricornis and B. atripes (see the key; Figs 41, 45, 69, 71) and very similar in its colour pattern of yellow with a black band between the wing bases to B. amurensis, B. distinguendus, B. filchnerae and B. anachoreta (see the key; Figs 15, 19, 41, 43, 47).
Distribution in North China. Widely distributed on the edge of the east Qinghai-Tibetan plateau, the Liupanshan mountains, the edge of the southern Neimenggu plateau close to Shanxi and Hebei, and the grasslands of northeastern Neimenggu. Common at medium elevations of the Liupanshan mountains in southern Ningxia and eastern Gansu, at medium elevations of the Bashang plateau in northern Hebei, at medium elevations of the transition zone between the edge of east Otindag semi-desert and the southernmost of the Great Khingan mountains, in Majiayingzi, Keshiketeng, Neimenggu, and at low elevations of the Hulunbeir grasslands in northeastern Neimenggu. Rare at medium elevations of the Baihuashan nature reserve in Beijing, at medium to high elevations of edge of the east Qinghai-Tibetan plateau in Gansu, and at medium elevations of the Taihangshan mountains and the Lvliangshan mountains in Shanxi. 62 localities (Fig. 40) between 215–3472 m (IAB).
Distribution in China. Beijing, Hebei, Shanxi, Neimenggu, Heilongjiang, Gansu, Qinghai, Ningxia, Xinjiang (IAB).
Forage plants. ASTERACEAE: Cosmos bipinnatus, Helianthus annuus, Saussurea stella; FABACEAE: Hedysarum gmelinii, Medicago sativa, Onobrychis viciifolia; GENTIANACEAE: Gentiana sp.; LAMIACEAE: Caryopteris tangutica, Dracocephalum heterophyllum, Elsholtzia densa, E. fruticosa; RANUNCULACEAE: Aconitum gymnandrum, Delphinium grandiflorum.
description: Published as part of An, Jiandong, Huang, Jiaxing, Shao, Youquan, Zhang, Shiwen, Wang, Biao, Liu, Xinyu, Wu, Jie & Williams, Paul H., 2014, The bumblebees of North China (Apidae, Bombus Latreille), pp. 1-89 in Zootaxa 3830 (1) on pages 33-34, DOI: 10.11646/zootaxa.3830.1.1, http://zenodo.org/record/286560
title: Dietary Taurine Alters Behavioral Responses to an Olfactory Stimulus in Sablefish (Anoplopoma fimbria)
Creators: name: Lee, Bong-Joo
name: Sommers, Frank
name: Armbruster, Lisa C.
name: Johnson, Ronald
Publisher: name: NOAA National Marine Fisheries Service Northwest Fisheries Science Center
publisherIdentifier: https://ror.org/05r7z1k40
publisherIdentifierScheme: ROR
Year: 2024

description: NOAA technical memorandum NMFS NWFSC ; 191
description: This study suggests that a lack of dietary taurine may affect olfactory function, which may negatively impact feeding response, reproduction, or other olfactory-mediated behaviors.
title: Компьютерная графика
Creators: name: ELS IPR BOOKS
Publisher: name: Международный университет Кыргызстана
Year: 2022

description: Это учебное пособие восполняет острую нехватку учебников по компьютерной графике для всех направлений второго курса УНПК Международного университета Кыргызстана. К главным достоинствам учебного пособия можно отнести сжатость изложения материала при полном раскрытии тем, обозначенных в стандарте, практические и контрольные работы, примеры, доступный язык изложения, что является весьма важным для такого учебного пособия, принимая во внимания уровень подготовки и восприятия аудитории.
title: Chemotaxonomische Untersuchungen an österreichischen Farnen
Creators: name: Rauch, Andreas Wendelin
Year: 2008

description: In der Volksmedizin Österreichs werden Farne als Mittel gegen rheumatische Beschwerden, Gelenkschmerzen und ähnliche Beschwerden eingesetzt. Dabei werden die Farne als Tinkturen für Einreibungen, als Badezusatz, als Polsterfüllungen oder direkt als Auflage verwendet [Lit. 1]. In einer vorangegangenen Diplomarbeit [Lit. 1] wurde eine Identifizierung der polaren Phenolcarbonsäuren und Flavonoide in Dryopteris dilatata (Hoffm.) A. Gray vorgenommen. Es konnten Caffeoyl-tatronat, Chlorogensäure und die Flavonoide Astragalin und Isoquercitrin identifiziert werden. Ausserdem wurde eine weitere Hauptkomponente detektiert, die aber nicht identifiziert werden konnte. Ein Teil dieser Diplomarbeit widmet sich der Identifizierung dieser Hauptkomponente. Der andere Teil der Diplomarbeit beschäftigt sich mit chemotaxonomischen Untersuchungen an Athyrium filix femina (L.) Roth, Athyrium distentifolium Tausch ex Opiz, Dryopteris dilatata und Dryopteris filix mas (L.) Schott. Im Rahmen der chemotaxonomischen Untersuchungen wurden Einzelpflanzenvergleiche, Standortvergleiche sowie Jahresvergleiche durchgeführt.
title: Информатика
Creators: name: ELS IPR BOOKS
Publisher: name: Международный университет Кыргызстана
Year: 2022

description: Это учебное пособие восполняет острую нехватку учебников по информатике для всех направлений первого курса Международного университета Кыргызстана. К главным достоинствам учебного пособия можно отнести сжатость изложения материала при полном раскрытии тем, обозначенных в стандарте, практические задания и примеры, доступный язык изложения, что является весьма важным для такого учебного пособия, принимая во внимание уровень подготовки и восприятия аудитории.
Bombus (Thoracobombus) filchnerae Vogt
Creators: name: An, Jiandong
name: Huang, Jiaxing
name: Shao, Youquan
name: Zhang, Shiwen
name: Wang, Biao
name: Liu, Xinyu
name: Wu, Jie
name: Williams, Paul H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Apidae
Bombus
Bombus filchnerae

description: 20. Bombus (Thoracobombus) filchnerae Vogt
(Figs 42, 43)
Bombus Filchnerae Vogt, 1908:100.
Agrabombus adventor Skorikov, 1914:119. Bombus (Agrobombus) lii Tkalců, 1961:355.
Material examined. 21 queens, 179 workers, 24 males (IAB).
Distribution in North China. Primarily on the edge of the northeast Qinghai-Tibetan plateau, the Liupanshan mountains, the Bashang plateau and the Hulunbeir grasslands. Common at medium elevations of the Qilianshan nature reserve in Gansu, at medium elevations of the Liupanshan nature reserve in southern Ningxia, at medium elevations of the loess plateau in eastern Gansu, and at low elevations of the Hulunbeir grasslands in northeastern Neimenggu. Rare at medium elevations of the Bashang plateau in northern Hebei, at medium elevations of the Taihangshan mountains in northern Shanxi, and at medium elevations of the sandy grasslands of the edge of the southern Neimenggu plateau. 44 localities (Fig. 42) between 602–2659 m (IAB).
Similar species in North China. This species is similar in its yellow colour pattern to some yellow B. amurensis, B. distinguendus, B. laesus and B. anachoreta (see the key; Figs 15, 19, 41, 43, 47).
Distribution in China. Hebei, Shanxi, Neimenggu, Gansu, Qinghai, Ningxia, Xinjiang (IAB).
Forage plants. ASTERACEAE: Cirsium leo, Helianthus annuus, Ligularia sagitta, Olgaea tangutica; FABACEAE: Medicago sativa, LAMIACEAE: Leonurus sibiricus, Salvia japonica.
description: Published as part of An, Jiandong, Huang, Jiaxing, Shao, Youquan, Zhang, Shiwen, Wang, Biao, Liu, Xinyu, Wu, Jie & Williams, Paul H., 2014, The bumblebees of North China (Apidae, Bombus Latreille), pp. 1-89 in Zootaxa 3830 (1) on pages 34-35, DOI: 10.11646/zootaxa.3830.1.1, http://zenodo.org/record/286560
title: Distributed Computing for the Optimization of Large-Scale Construction Projects
Creators: name: El-Rayes, Khaled
name: Kandil, Amr
Publisher: name: Bauhaus-Universität Weimar
Year: 2004
Subjects: subject: Baubetrieb
subject: Computerunterstütztes Verfahren
subject: Verteiltes System
subject: Planung
subject: Großbaustelle
subject: Optimal Planning
subject: 620

description: Available construction time-cost trade-off analysis models can be used to generate trade-offs between these two important objectives, however, their application is limited in large-scale construction projects due to their impractical computational requirements. This paper presents the development of a scalable and multi-objective genetic algorithm that provides the capability of simultaneously optimizing construction time and cost large-scale construction projects. The genetic algorithm was implemented in a distributed computing environment that utilizes a recent standard for parallel and distributed programming called the message passing interface (MPI). The performance of the model is evaluated using a set of measures of performance and the results demonstrate the capability of the present model in significantly reducing the computational time required to optimize large-scale construction projects.
description: X. International Conference on Computing in Civil and Building Engineering: proceedings ; [ICCCBE], Weimar, June 02-04, 2004, vol. 2004
Additional file 4 of Insights into physical activity promotion among Australian chiropractors: a cross-sectional survey
Creators: name: Fernandez, Matthew
name: de Luca, Katie
name: Moore, Craig
name: French, Simon D.
name: Ferreira, Paulo
name: Swain, Michael
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health

description: Supplementary Material 4
title: Учебное пособие по выполнению практических заданий по дисциплине «Информатика»
Creators: name: ELS IPR BOOKS
Publisher: name: Международный университет Кыргызстана
Year: 2022

description: Учебное пособие составлено с учетом требований Кыргызского государственного образовательного стандарта высшего образования, предназначено для практического изучения дисциплины — «Информатика». Пособие включает документы по практическому применению возможностей программы MS Office 2016 в составлении документов, работе с ними, состав методических указаний размещен в трех разделах, рекомендации по изучению документов по темам, основные понятия каждой темы, вопросы для анализа, список рекомендованной литературы, примерные тесты по каждому разделу. Пособие предназначено для обучающихся по всем направлениям по дисциплине «Информатика».
Sialylated autoantigen-reactive IgG antibodies attenuate disease development in mouse models of lupus nephritis and rheumatoid arthritis
Creators: name: Rahmöller, Johann
name: Bartsch, Yannic C.
name: Leliavski, Alexei
name: Lilienthal, Gina-Maria
name: Petry, Janina
name: Ehlers, Marc
Publisher: name: Advances in RAB Research
Year: 2018

description: Pro- and anti-inflammatory effector functions of IgG antibodies (Abs) depend on their subclass and Fc glycosylation pattern. Accumulation of non-galactosylated (agalactosylated; G0) IgG Abs in the serum of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) patients reflects severity of the diseases. In contrast, sialylated IgG Abs are responsible for anti-inflammatory effects of the intravenous immunoglobulin (IVIG; pooled human serum IgG from healthy donors), administered in high doses (2 g/kg) to treat autoimmune patients. However, whether low amounts of sialylated autoantigen-reactive IgG Abs can also inhibit autoimmune diseases has been hardly investigated. Here, we explored whether sialylated autoantigen-reactive IgG Abs can inhibit autoimmune pathology in two mouse models (Bartsch et al., Front. Immunol. 2018; 9:1183). We found that sialylated IgG autoantibodies fail to induce inflammation and lupus nephritis in a B cell receptor (BCR) transgenic lupus model, but instead are associated with lower frequencies of pathogenic Th1, Th17 and B cell responses. In accordance, the transfer of small amounts of immune complexes containing sialylated IgG Abs was sufficient to attenuate the development of nephritis. We further showed that administration of sialylated collagen type II (Col II)-specific IgG Abs attenuated the disease symptoms in a model of Col II-induced arthritis and reduced pathogenic Th17 cell and autoantigen-specific IgG Ab responses. We conclude that sialylated autoantigen-specific IgG Abs may represent a promising tool for treating pathogenic T and B cell immune responses in autoimmune diseases.
description: Advances in RAB Research, Vol 1 No 1 (2018)
Autoantibodies targeting complement receptors 3a and 5a are decreased in ANCA-associated vasculitis
Creators: name: Klapa, Sebastian
name: Koch, Andreas
name: Kerstein, Anja
name: Karsten, Christian
name: Heidecke, Harald
name: Huber-Lang, Markus
name: Lamprecht, Peter
name: Riemekasten, Gabriela
name: Müller, Antje
Publisher: name: Advances in RAB Research
Year: 2018

description: Introduction: Necrotizing crescentic glomerulonephritis (NCGN) is a pathogenic hallmark of full-blown ANCA-associated vasculitis (AAV). In AAV, NCGN is characterized by scantly deposited immune complexes and involvement of the complement system. The relevance of the latter in AAV is reflected by elevated amounts of circulating C5a and, foremost, by protection from NCGN through blockade of C5aR1. In contrast, little if any is known about autoantibodies recognizing complement receptors 3a and 5a in AAV patients.
Methods: To examine the presence of autoantibodies directed against complement receptor C3a (C3aR) and C5a (C5aR1) in AAV, sera of patients with AAV [granulomatosis with polyangiitis (GPA), n=49 and microscopic polyangiitis (MPA), n=10] were measured by Elisa in comparison to healthy controls (HC, n=127). In addition, amounts of circulating C3a and C5a were determined by Elisa. Clinical parameters (BVAS, VDI, therapy) and disease marker (ESR, CRP, creatinine, anti-PR3, anti-MPO) were gathered at the time of serum sampling.
Results: Unlike MPA, in GPA lower titers of anti-C3aR were observed in comparison to HC. In addition, the concentration of anti-C5aR1 was decreased in both, GPA and MPA when compared to HC. In particular, GPA patients without a history of therapy using cyclophosphamide and/or rituximab exhibited a negative correlation between the concentration of anti-C5aR1 and the disease activity (BVAS).
Conclusion: The results may give a hint that anti-C3aR and anti-C5aR1 antibodies play distinct roles in GPA and MPA. Further, anti-C5aR1 might be of diagnostic value to monitor the clinical progress of GPA.
description: Advances in RAB Research, Vol 1 No 1 (2018)
The D/H ratio in Titan's acetylene from high spectral resolution IRTF/TEXES observations
Creators: name: Bézard, B.
name: Nixon, C. A.
name: Vinatier, S.
name: Lellouch, E.
name: Greathouse, T.
name: Giles, R.
name: Lombardo, N. A.
name: Jolly, A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We report observations of deuterated acetylene (C$_2$HD) at 19.3 $μ$m (519 cm$^{-1}$) with the Texas Echelon Cross Echelle Spectrograph on the NASA Infrared Telescope Facility in July 2017. Six individual lines from the Q-branch of the $ν_4$ band were clearly detected with a S/N ratio up to 10. Spectral intervals around 8.0 $μ$m (745 cm$^{-1}$) and 13.4 $μ$m (1247 cm$^{-1}$) containing acetylene (C$_2$H$_2$) and methane (CH$_4$) lines respectively, were observed during the same run to constrain the disk-averaged C$_2$H$_2$ abundance profile and temperature profile. Cassini observations with the Composite Infrared Spectrometer (CIRS) were used to improve the flux calibration and help to constrain the atmospheric model. The measured D/H ratio in acetylene, derived from the C$_2$HD/C$_2$H$_2$ abundance ratio, is (1.22$^{+0.27}_{-0.21})$ $\times$ 10$^{-4}$, consistent with that in methane obtained in previous studies. Possible sources of fractionation at different steps of the acetylene photochemistry are investigated.
Impact of regulatory (auto-)antibodies against G-protein-coupled receptors on blood pressure in women ten years after early-onset preeclampsia
Creators: name: Birukov, Anna
name: Muijsers, Hella
name: Heidecke, Harald
name: Haase, Nadine
name: Kräker, Kristin
name: Müller, Dominik N.
name: Herse, Florian
name: Maas, Angela
name: Dechend, Ralf
Publisher: name: Advances in RAB Research
Year: 2018

description: Introduction: Preeclampsia (PE) is associated with an increased cardiovascular risk in later life, especially in women after early-onset PE. We and others have shown that activating antibodies against angiotensin II receptor type 1 (AT1-) are present in women with PE, even after pregnancy. Further, regulatory (auto-) antibodies against G-coupled receptors (GPCR) have been shown to contribute to cardiovascular disease.
Hypothesis: Regulatory autoantibodies’ titers are elevated in women with a history of early onset PE and correlate to physiological parameters and clinical outcomes.
Methods: Autoantibodies against AT1-, β1- adrenergic receptors, endothelin I receptor A (ETAR), protease-activated receptor 1 (PAR1) and C-X-C3 chemokine binding receptors (CXCR3) were determined by using commercially available ELISA (Celltrend, Luckenwalde, Germany) in women 10 years after after PE pregnancy or control pregnancy. We investigated samples from the PREVFEM cohort (PReeclampsia Risk EValuation in FEMales), a retrospective matched case-control study, which was performed in Zwolle, The Netherlands, from 2008 until 2010. All women registered in the early preeclampsia database as well as an equal number of age-matched females without preeclampsia from the regular obstetric database in the same time period (1991-2007) were invited to participate in the PREVFEM study.
Results: Women with history of early PE had higher prevalence of hypertension than controls (42.7% vs 8.3%, p < 0.001). Women with the lowest combined levels of autoantibodies and a history of early PE had significantly higher SBP (mean difference = 11.54 mmHg, 95% CI [4.39; 18.70], p < 0.001), DBP (mean difference = 7.75 mmHg, 95% CI [2.42; 13.08], p < 0.001), and MAP (mean difference = 9.02 mmHg, 95% CI [3.24; 14.79], p < 0.001) compared to the controls. The titer levels of single regulatory AT1-, β1-, ETAR-, PAR1- and CXCR3-autoantibodies were not different between control and former PE women 10 years after index pregnancy.
Conclusions: Hypertension is a common problem after preeclamptic pregnancy in middle-aged women. Regulatory autoantibodies are not sufficient alone to cause hypertension or other pathologic conditions, but together with other risk factors such as pathological pregnancy might drive the whole balance towards pathophysiologic conditions. Further studies are needed to investigate the potential of regulatory autoantibodies against GPCR as presymptomatic biomarkers identifying women at particular cardiovascular risk.
description: Advances in RAB Research, Vol 1 No 1 (2018)
Immunoadsorption in Vascular Dementia
Creators: name: Grabe, Hans Jörgen
Publisher: name: Advances in RAB Research
Year: 2018

description: The pathomechanisms leading to Alzheimer´s Disease (AD) are not well understood. Despite several robust hypotheses the nature of the disease seems to be more complex than initially thought. The role of vascular components of AD have been underestimated so far. In this novel treatment approach we perform immunoadsorption over 5 days to remove agonistic autoantibodies (AAB) against α1A-adrenoceptor from the plasma of AD patients. These AAB are thought to alter the functional properties of small blood vessels leading to malfunctions in the supply and clearance processes of the brain.
We will present the first 5 patients with AD who underwent immunoabsorption and who completed a 12-months follow up. Clinical, cognitive and MRI data as well as peripheral endothelial function data and data on AAB clearance will be presented.


The study is funded by Fresenius Medical Care.
description: Advances in RAB Research, Vol 1 No 1 (2018)
Bombus (Thoracobombus) muscorum Linnaeus
Creators: name: An, Jiandong
name: Huang, Jiaxing
name: Shao, Youquan
name: Zhang, Shiwen
name: Wang, Biao
name: Liu, Xinyu
name: Wu, Jie
name: Williams, Paul H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Apidae
Bombus
Bombus muscorum

description: 21. Bombus (Thoracobombus) muscorum (Linnaeus)
(Figs 44, 45)
Apis Mucorum [muscorum] Linnaeus, 1758:579.
Material examined. 1 worker, 2 males (IAB).
Distribution in North China. Rare at low elevations of the Hulunbeir grasslands and the Nenjiang river valley in northeastern Neimenggu. 3 localities (Fig. 44) between 315–678 m (IAB).
Similar species in North China. This species is very similar in its orange-brown colour pattern to some B. laesus, B. tricornis and B. atripes (see the key; Figs 41, 45, 69, 71)
Distribution in China. Neimenggu, Heilongjiang, Xinjiang (IAB).
Forage plants. ASTERACEAE: Helianthus annuus; ONAGRACEAE: Chamerion angustifolium.
description: Published as part of An, Jiandong, Huang, Jiaxing, Shao, Youquan, Zhang, Shiwen, Wang, Biao, Liu, Xinyu, Wu, Jie & Williams, Paul H., 2014, The bumblebees of North China (Apidae, Bombus Latreille), pp. 1-89 in Zootaxa 3830 (1) on pages 35-36, DOI: 10.11646/zootaxa.3830.1.1, http://zenodo.org/record/286560
title: Национальная экономика
Creators: name: ELS IPR BOOKS
Publisher: name: Международный университет Кыргызстана
Year: 2019

description: Национальная экономика находится в тесной взаимосвязи с экономикой страны. Изучение представленного курса создает основу для рассмотрения макро-, мезо и микроэкономических отношений с учетом целостности и комплексности национальной экономики и инструментов ее функционирования и развития. Учебно-методическое пособие представляет собой системно-методологическое изложение курса национальной экономики. Он состоит из следующих разделов: цели и задачи курса, сетка аудиторных часов, тематика и краткое содержание лекций, тематика и план семинарских занятий, контрольные вопросы по темам, тесты, рекомендуемая литература. Пособие рассчитано для студентов и преподавателей экономических учебных заведений Республики.
Additional file 5 of Insights into physical activity promotion among Australian chiropractors: a cross-sectional survey
Creators: name: Fernandez, Matthew
name: de Luca, Katie
name: Moore, Craig
name: French, Simon D.
name: Ferreira, Paulo
name: Swain, Michael
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health

description: Supplementary Material 5
Bombus (Thoracobombus) anachoreta Skorikov
Creators: name: An, Jiandong
name: Huang, Jiaxing
name: Shao, Youquan
name: Zhang, Shiwen
name: Wang, Biao
name: Liu, Xinyu
name: Wu, Jie
name: Williams, Paul H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Apidae
Bombus
Bombus anachoreta

description: 22. Bombus (Thoracobombus) anachoreta (Skorikov)
(Figs 46, 47)
Agrobombus anachoreta Skorikov, 1914:121.
Material examined. 7 workers, 5 males (IAB).
Distribution in North China. Common at low elevations on the edge of the farmland of the Nenjiang river valley in northeastern Neimenggu. 2 localities (Fig. 46) between 215–240 m (IAB).
Similar species in North China. This species is similar in its yellow colour pattern to some yellow B. amurensis, B. distinguendus, B. laesus and B. filchnerae, (see the key; Figs 15, 19, 41, 43, 47).
Distribution in China. Neimenggu, Heilongjiang (IAB).
Forage plants. ASTERACEAE: Cosmos bipinnatus.
description: Published as part of An, Jiandong, Huang, Jiaxing, Shao, Youquan, Zhang, Shiwen, Wang, Biao, Liu, Xinyu, Wu, Jie & Williams, Paul H., 2014, The bumblebees of North China (Apidae, Bombus Latreille), pp. 1-89 in Zootaxa 3830 (1) on page 36, DOI: 10.11646/zootaxa.3830.1.1, http://zenodo.org/record/286560
title: Die Steinätzung von Rosegg
Creators: name: Jäger, Yvonne Silke
Year: 2010

description: Diese Arbeit behandelt eine 77, 5 cm hohe und 90 cm breite Tischplatte aus Solnhofer Stein, datiert auf das Jahr 1579. Derzeit befndet sich die Platte in der Pfarrkirche St. Michael in Rosegg in Kärntnen, eingemauert in die linke Wand des Presbyteriums. Es handelt sich hierbei um eine Steinätzung, eine Technik, die vor allem im 16. Jahrhundert üblich war. Allerdings war es selten Noten zu ätzen, was diese Tischplatte zu einer Besonderheit macht. Neben der lateinischen Kontrafaktur der vierstimmigen Chanson des Komponisten Pierre Sandrin, befinden sich auf der Platte 6 Medaillons mit Tierfiguren, ein Gebet des reformatorischen Schriftstellers Jörg Berckenmayer, ein freies Gebet, eine kurze Abhandlung der Vier letzten Dinge und in der Mitte ein Bild der Kreuzigung Christi. Das Thema der Platte ist die ars moriendi, die Kunst des Sterbens. Gerade das Nachdenken über den Tod und die Vorbereitung der letzten Stunde war im 15. und 16. Jahrhundert sehr populär. In meiner Arbeit wird nun der Versuch unternommen die auf der Tischplatte befindlichen Texte, Bilder und das Musikstück vor allem theologisch, aber auch historisch einzuordnen und mit ähnlichen Werken zu vergleichen. Bilder der Platte sind in der Arbeit vorhanden.
Agonistic antibody diseases = Autoimmune diseases?
Creators: name: Kunze, Rudolf
Publisher: name: Advances in RAB Research
Year: 2018

description: In recent years, the number of diseases in which autoantibodies (AAB) against G Protein-coupled receptors (GPCR) have been detected has continued to increase. Because they act in a bioassay similar to the physiological ligands of GPCR, the term "agonistic autoantibodies" (agAAB) was established early on. The proportion of patients with a clinically diagnosed disease in whom agAAB has been detected in the blood can be very different. Currently agAAB can be determined against 8 different GPCRs. The probably most important ones are directed against the adrenoceptors (AR) α, ß1, ß2 and the angiotensin2 receptor type 1 (AT1-R). The AAB binding epitopes are located on the extracellular 1st or 2nd loop and are consistently constant.
For a few diseases such as dilated cardiomyopathy (DCM, ß1-AR, α-AR), pre-eclampsia (AT1-R) and vascular necrotic kidney transplant rejection (AT1-R), antibodies could be induced in animal experiments by immunisation with the extracellular loop peptides and subsequently produce a disease pattern similar to that of humans. In the development of vascular M. Alzheimer's disease (VAD), animal experimental findings according to agAAK against α-AR could also play a role in cerebral vascular obliteration. For most of the diseases associated with agAAB, the pathological significance of the proven agAAB has not yet been clarified. They may be an epiphenomenon, but can also be pathologically amplifying bystander or even cause the disease.
The above agAABs often occur in typical combinations, and we do not yet know anything about their possible interference or parallel involvement in the respective disease. The distribution patterns of agAAK in diseases such as DCM, VAD, diabetes type 2 (DM2), primary open-angle glaucoma (POAG), thromboangiitis obliterans (TAO) or chronic fatigue syndrome (CFS) observed so far suggest that there are pathophysiological similarities between the very different diseases in the clinical symptoms. This is particularly noticeable in diseases with vascular contribution.
Up to now, agAAB's participation in a disease beyond the classics such as DCM has not been taken into account therapeutically. The abundance of data on the prevalence of agAAB in a wide variety of diseases makes it almost necessary to search for new terms to take these conditions into account. One possible approach would be to label patients with different diagnoses and positive antibody status with the additional diagnosis"agonistic antibody disease". In specific individual cases, new therapeutic options may then become apparent.
description: Advances in RAB Research, Vol 1 No 1 (2018)
Autoantibodies in serum of systemic scleroderma patients: peptide-based epitope mapping indicates increased binding to cytoplasmic domains of CXCR3
Creators: name: Recke, Andreas
name: Regensburger, Ann-Katrin
name: Weigold, Florian
name: Müller, Antje
name: Marschner, Gabriele
name: Heidecke, Harald
name: Marschner, Gabriele
name: Hammers, Christoph M
name: Ludwig, Ralf J.
name: Riemekasten, Gabriela
Publisher: name: Advances in RAB Research
Year: 2018

description: Introduction: Systemic sclerosis (SSc) is a severe chronic autoimmune disease with high morbidity and mortality. Sera of patients with SSc contain a large variety of autoantibody (aab) reactivities. Among these are functionally active aab that bind to G protein-coupled receptors (GPCR) such as C-X-C motif chemokine receptor 3 (CXCR3) and 4 (CXCR4). Aab binding to the N-terminal portion of these two GPCRs have been shown to be associated with slower disease progression in SSc, especially deterioration of lung function.
Methods: We used peptide ELISA with serum samples in combination with a hierarchical Bayesian model for mapping of epitopes on CXCR3. For in silico prediction of epitopes on CXCR3, we used the ABCpred online tool.
Results: To identify linear epitopes of anti-CXCR3 aabs, we used a peptide array of 36 overlapping 18-20mer peptides covering the entire CXCR3 sequence for ELISA to compare the binding pattern of SSc patient sera (N=32) and healthy controls (N=30). We found increased binding of SSc patient sera to intracellular epitopes within CXCR3, while the binding signal to extracellular portions of CXCR3 was found to be reduced in Ssc patients. Experimentally determined epitopes showed a good correspondence to those predicted by the ABCpred tool. To verify these results and to translate them into a novel diagnostic ELISA, we combined the peptides that represent SSc-associated epitopes into a single ELISA and evaluated its potential to discriminate SSc patients (N=31) from normal healthy controls (N=47). This ELISA had a sensitivity of 0.61 and a specificity of 0.85.
description: Advances in RAB Research, Vol 1 No 1 (2018)
title: Международное публичное право
Creators: name: ELS IPR BOOKS
Publisher: name: Международный университет Кыргызстана
Year: 2021

description: Краткое содержание лекционного курса дает возможность передачи информации для большого количества слушателей за относительно короткий промежуток времени. В процессе изучения международного права студенты овладевают концепцией политического мышления в международных отношениях, самостоятельно анализировать международную обстановку на основе существующих международно-правовых норм. Рассчитана для слушателей, обучающихся на факультете дистанционного обучения по специальности «юриспруденция».
A Resonant Cavity-Based CRES Demonstrator on the Path to a Neutrino Mass Measurement with Project 8
Creators: name: Novitski, Elise
name: Peña, Junior
name: Stachurska, Juliana
name: Van De Pontseele, Wouter
Publisher: name: Zenodo
Year: 2024
Subjects: Neutrino mass

description: Track: Neutrino mass
Bombus (Thoracobombus) opulentus Smith
Creators: name: An, Jiandong
name: Huang, Jiaxing
name: Shao, Youquan
name: Zhang, Shiwen
name: Wang, Biao
name: Liu, Xinyu
name: Wu, Jie
name: Williams, Paul H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Apidae
Bombus
Bombus opulentus

description: 23. Bombus (Thoracobombus) opulentus Smith
(Figs 48, 49)
Bombus opulentus Smith, 1861:153.
Material examined. 8 queens, 328 workers, 24 males (IAB).
Distribution in North China. Primarily on the Bashang plateau, the Yanshan mountains, the Taihangshan mountains, the loess plateau and the Qinling mountains. Abundant at low elevations of the Simatai Greatwall scenic spots of the Yanshan mountains in Beijing. Common at low elevations of the Bashang plateau and at medium elevations of the Wulingshan nature reserve in Hebei, at medium elevations of the Ziwuling nature reserve and the Maijishan forest park in Gansu, at low elevations of the Fuping nature reserve in Shaanxi. Rare at low to medium elevations of the Panshan forest park, the Shangfangshan forest park, the Lingshan nature reserve, the Puwa nature reserve in Beijing, at low elevations of the Jiudingshan forest park in Tianjin, at low to medium elevations of the Taihangshan mountains in Shanxi, at medium elevations of the loess plateau in northern Shaanxi, at medium elevations of the Xiaolongshan nature reserve and the Baishangjiang nature reserve, at high elevations of the Gahai nature reserve in Gansu, and at medium elevations of the Liupanshan nature reserve in southern Ningxia. 78 localities (Fig. 48) between 65–3432 m (IAB).
Similar species in North China. This species is similar in its brown and black colour pattern to B. longipes (see the key; Figs 23, 49).
Distribution in China. Beijing, Tianjin, Hebei, Shanxi, Shaanxi, Gansu, Ningxia (IAB).
Forage plants. ASTERACEAE: Arctium lappa, Cirsium shansiense, Cosmos bipinnatus, Helianthus annuus, H. tuberosus, Senecio laetus; Solidago canadensis; CUCURBITACEAE: Thladiantha dubia; CONVOLVULACEAE: Merremia sibirica, Ipomoea purpurea; FABACEAE: Astragalus adsurgens, A. dahuricus, Campylotropis macrocarpa, Lablab purpureus, Lespedeza bicolor, L. juncea, Melilotus albus, Onobrychis viciifolia, Vicia amoena, V. cracca; LAMIACEAE: Elsholtzia ciliata, E. stauntonii, Leonurus japonicus, L. macranthus, L. sibiricus, Phlomis umbrosa, Salvia deserta, S. farinacea, Stachys chinensis, Vitex negundo; MALVACEAE: Hibiscus syriacus; ROSACEAE: Duchesnea indica; SOLANACEAE: Solanum nigrum, S. septemlobum.
description: Published as part of An, Jiandong, Huang, Jiaxing, Shao, Youquan, Zhang, Shiwen, Wang, Biao, Liu, Xinyu, Wu, Jie & Williams, Paul H., 2014, The bumblebees of North China (Apidae, Bombus Latreille), pp. 1-89 in Zootaxa 3830 (1) on pages 36-37, DOI: 10.11646/zootaxa.3830.1.1, http://zenodo.org/record/286560