cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
UNRAVELING THE RHETORIC: THE CHALLENGES OF ANTI-CHINA CAMPAIGNS
Creators: name: Bennett Taylor, Olivia
name: Cooper, Jordan Mason
Publisher: name: Zap journal
Year: 2024
Subjects: U.S. presidential elections
Campaign advertising
Anti-China rhetoric
Voter support Campaign spending.

description: Money has historically played a pivotal role in U.S. presidential elections, but its influence is not always determinative of electoral outcomes. This study delves into the intriguing phenomenon where candidates, despite substantial financial advantages, failed to secure victory. By focusing on the utilization of campaign advertising, particularly the strategic deployment of anti-China rhetoric, we investigate how excessive spending on such advertisements can potentially backfire for candidates. In the realm of American presidential politics, anti-China rhetoric has become a recurrent theme, with candidates leveraging it to accuse opponents of policies favoring China at the expense of American interests. However, empirical investigations into the effectiveness of these rhetoric-driven strategies in garnering voter support remain scarce. This article addresses this research gap by employing a scientific methodology to assess the impact of anti-China rhetoric in campaign ads. We specifically examine whether the substantial financial investments made by presidential candidates in airing anti-China advertisements yield the desired electoral benefits or inadvertently harm their prospects. Our analysis draws upon data from Mitt Romney's 2012 "Failing American Workers" campaign commercial, sourced from the Wesleyan Media Project (WMP). Utilizing Time Series-Cross-Sectional (TSCS) models, we estimate the influence of the anti-China rhetoric within this ad on Romney's voter support. Our findings reveal a nuanced relationship between anti-China rhetoric in campaign advertising and candidate performance.
Supplementary document for Theoretical limits of passive daytime radiative cooling in extraterrestrial environments: Implications for space exploration - 7395025.pdf
Creators: name: Cheng, Jie
name: Zhang, Jiaping
name: Shao, Hanzhuo
name: Huang, Xuemei
name: Xu, Hua
name: Wang, Ke
name: Lv, Hongyu
name: Wang, Yunzhe
name: Xu, Xuesen
name: Song, Weijie
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supporting Information
MOSH DONINI DUKKAKLARIDAN AJRATIB DASTLABKI TOZALAYDIGAN QURILMANING TAJRIBA NUSXASINI ISHLAB CHIQISH USULI VA NATIJASI
Creators: name: Achilov, Elyor
Publisher: name: Zenodo
Year: 2024

description: Savag‘ichlar pichoqsimon tayyorlanganida mosh donini dukkaklaridan ajratib dastlabki tozalash texnologik jarayoni talab darajasidaamalga oshiriladi va 98,5 foizni tashkil etib, shikastlanish darajasining eng kam bo‘lishi, don tozaligi yuqori va nobudgarchiligi kam bo‘lishi ta’minlanadi.
MPEC 2024-G195 : 2024 GK5
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 GK5

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Transcriptome mining, functional characterization, and phylogeny of a large terpene synthase gene family in spruce (Picea spp.)
Creators: name: Keeling, Christopher I
name: Weisshaar, Sabrina
name: Ralph, Steven G
name: Jancsik, Sharon
name: Hamberger, Britta
name: Dullat, Harpreet K
name: Bohlmann, Jörg
Publisher: name: BioMed Central
Year: 2015

description: Background. In conifers, terpene synthases (TPSs) of the gymnosperm-specific TPS-d subfamily form a diverse array of mono-, sesqui-, and diterpenoid compounds, which are components of the oleoresin secretions and volatile emissions. These compounds contribute to defence against herbivores and pathogens and perhaps also protect against abiotic stress. Results The availability of extensive transcriptome resources in the form of expressed sequence tags (ESTs) and full-length cDNAs in several spruce (Picea) species allowed us to estimate that a conifer genome contains at least 69 unique and transcriptionally active TPS genes. This number is comparable to the number of TPSs found in any of the sequenced and well-annotated angiosperm genomes. We functionally characterized a total of 21 spruce TPSs: 12 from Sitka spruce (P. sitchensis), 5 from white spruce (P. glauca), and 4 from hybrid white spruce (P. glauca × P. engelmannii), which included 15 monoterpene synthases, 4 sesquiterpene synthases, and 2 diterpene synthases. Conclusions The functional diversity of these characterized TPSs parallels the diversity of terpenoids found in the oleoresin and volatile emissions of Sitka spruce and provides a context for understanding this chemical diversity at the molecular and mechanistic levels. The comparative characterization of Sitka spruce and Norway spruce diterpene synthases revealed the natural occurrence of TPS sequence variants between closely related spruce species, confirming a previous prediction from site-directed mutagenesis and modelling.
Garden peas and cabbage plants: A short 'de-simplified genetics' activity
Creators: name: Kalas, Pamela
Publisher: name: QUBES Educational Resources
Year: 2024

description: Are plants of genotype T/T tall? Are those of genotype t/t short? Let's find out in this short activity entirely based on a segment of: Smith's (2014) "It’s Not Your Grandmother’s Genetics Anymore!"
Deliverable 6.1: Guidelines and manual for applying the Health Social  Labs methodology
Creators: name: Pellegrini, Giuseppe
name: Lovati, Chiara
name: Schreck, Tobias
name: Silvello, Gianmaria
name: Romanovych, Anna
Publisher: name: Zenodo
Year: 2024

description: Health Social Laboratories represent an opportunity for project stakeholders to co-design and give feedback on Hereditary research processes and perspective research outputs design, such as the prototype of the interactive data analytics platform and the medical terminology popularization process. They would achieve the latter by helping analyse innovative ideas and perceptions regarding elements such as terminology, technology, and social and ethical issues.

The following manual begins with a brief overview of the concept of stakeholder engagement, its history, strengths and weaknesses, and then delves into the Exploratory Context Analysis conducted with project partners connected to Hereditary Use Cases and its results on the state of: relationships and stakeholders; therapeutic process and clinical activities; technology and research; communication, expertise and policymaking.

The following section, concretely containing HSL guidelines is divided into 7 chapters:

1. Objectives2. Operations and organisational processes3. Stakeholders4. Activities5. Staff6. Recording and reporting7. Evaluation

Each chapter contains specific methodological instructions and guidelines for the realization of the laboratories with necessary forms. Finally, the attached HSL manual Annex contains stand-alone editable versions of all forms, worksheets and presentations provided.
title: OF PATTERNS, ARCHIVES, AND RESISTANCE
title: QUILTING AS A TOOL FOR ACTIVISM, DISSENT, AND AS AN ART PRACTICE
titleType: Subtitle
Creators: name: Savelyeva, Liudmila
Publisher: name: The Dynamic Archive
Year: 2024
Subjects: Digital Media
Photography
Sound / Music
Textile

description: This component is part of my research on archiving different expressions of resistance and on the patchwork quilt that serves as a temporary residence for it. Chosen for its links with cultural heritage and the history of protests, the quilt as a host for the elements of the archive deliminates and challenges the classic notion of an archive.
Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in Trypanosoma cruzi strains revealed by array comparative genomic hybridization
Creators: name: Minning, Todd A
name: Weatherly, D B
name: Flibotte, Stephane
name: Tarleton, Rick L
Publisher: name: BioMed Central
Year: 2015

description: Background: Trypanosoma cruzi is a protozoan parasite and the etiologic agent of Chagas disease, an important public health problem in Latin America. T. cruzi is diploid, almost exclusively asexual, and displays an extraordinarily diverse population structure both genetically and phenotypically. Yet, to date the genotypic diversity of T. cruzi and its relationship, if any, to biological diversity have not been studied at the whole genome level. Results In this study, we used whole genome oligonucleotide tiling arrays to compare gene content in biologically disparate T. cruzi strains by comparative genomic hybridization (CGH). We observed that T. cruzi strains display widespread and focal copy number variations (CNV) and a substantially greater level of diversity than can be adequately defined by the current genetic typing methods. As expected, CNV were particularly frequent in gene family-rich regions containing mucins and trans-sialidases but were also evident in core genes. Gene groups that showed little variation in copy numbers among the strains tested included those encoding protein kinases and ribosomal proteins, suggesting these loci were less permissive to CNV. Moreover, frequent variation in chromosome copy numbers were observed, and chromosome-specific CNV signatures were shared by genetically divergent T. cruzi strains. Conclusions The large number of CNV, over 4,000, reported here uphold at a whole genome level the long held paradigm of extraordinary genome plasticity among T. cruzi strains. Moreover, the fact that these heritable markers do not parse T. cruzi strains along the same lines as traditional typing methods is strongly suggestive of genetic exchange playing a major role in T. cruzi population structure and biology.
Manifesto for a Radical Planning *UK-Ireland Planning Research Conference.* Reading, 2-4 September
Creators: name: Chapman, Kiera
name: Inch, Andy
name: Slade, Jason
name: Tait, Malcolm
Publisher: name: The University of Sheffield
Year: 2024
Subjects: classificationCode: 330499
subject: Urban and regional planning not elsewhere classified

description: Presented at the UK-Ireland Planning Research Conference 2024Planning has never been radical. This is how it could be. In this roundtable, a group of scholars from the University of Sheffield will discuss their ‘Manifesto for a Radical Planning’: a series of propositions to change current planning theory and practice. Expect a provocative discussion that will challenge everything from neoliberalism, land and property ownership, and the idea of planning ‘balance’, to the troubling coloniality of planning history and the damaging environmental impacts of new ‘natural capital’ methodologies. Shots will be fired!
D3.1 LIST OF OPERATIONAL KPIS, ANALYSIS OF THE USERS' SATISFACTION AND METHODOLOGY AS A WHOLE C-REL
Creators: name: Santarremigia, Francisco
Publisher: name: Zenodo
Year: 2021

description: Deliverable D3.1 List of operational KPIs, analysis of the users’ satisfaction, and methodology as a whole, C-REL provides the preliminary information for consistent monitoring of IP4 (Innovation Programme 4) solutions in real environments and a market acceptance analysis through the assessment of needs and expectations of current and future travellers and TSPs when using IP4 solutions.
Manifesto for a Radical Planning
Creators: name: Chapman, Kiera
name: Inch, Andy
name: Slade, Jason
name: Tait, Malcolm
Publisher: name: The University of Sheffield
Year: 2024
Subjects: classificationCode: 330499
subject: Urban and regional planning not elsewhere classified

description: Presented at the UK-Ireland Planning Research Conference 2024Planning has never been radical. This is how it could be. In this roundtable, a group of scholars from the University of Sheffield will discuss their ‘Manifesto for a Radical Planning’: a series of propositions to change current planning theory and practice. Expect a provocative discussion that will challenge everything from neoliberalism, land and property ownership, and the idea of planning ‘balance’, to the troubling coloniality of planning history and the damaging environmental impacts of new ‘natural capital’ methodologies. Shots will be fired!
Supporting information file from CO2 Hydrogenation to methanol over Pt Functionalized Hf- versus Zr-UiO-67
Creators: name: Sannes, Dag Kristian
name: Pulumati, Sri Harsha
name: Skulason, Egil
name: Flores, Ainara Nova
name: Olsbye, Unni
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 340204
subject: Inorganic green chemistry
classificationCode: 340504
subject: Organic green chemistry

description: HfZr comparison study manuscript_final_SI_revised.docx
title: Palm Off the “Red Gold:” Headwinds for EU Palm Oil Trade?
Creators: name: Lee, Ivan
Publisher: name: United States International Trade Commission
publisherIdentifier: https://ror.org/05hsggr76
publisherIdentifierScheme: ROR
Year: 2024

description: In 2023, the European Union (EU) enacted the EU Deforestation Regulation (EUDR), preventing
commodities linked with deforestation and forest degradation from entering the EU market. The antideforestation regulation applies to a wide range of products such as palm oil, soy, wood, cocoa, coffee,
rubber, and cattle, as well as their derivative products like chocolate, leather, and cosmetics. Malaysia and
Indonesia, the world’s top two palm oil producers and exporters, have raised official concerns that EUDR
as well as other related EU policies could negatively impact their palm oil exports to the EU. This EBOT
discusses the EU regulatory environment and its impact on EU palm oil – known to some as ‘red gold’ –
trade.
Estimating the impact of expanded access to antiretroviral therapy on maternal, paternal and double orphans in sub-Saharan Africa, 2009-2020
Creators: name: Anema, Aranka
name: Au-Yeung, Christopher G.
name: Joffres, Michel
name: Kaida, Angela
name: Vasarhelyi, Krisztina
name: Kanters, Steve
name: Montaner, Julio
name: Hogg, Robert S.
Publisher: name: BioMed Central
Year: 2016

description: Background: HIV/AIDS has orphaned 11.6 million children in sub-Saharan Africa. Expanded antiretroviral therapy (ART) use may reduce AIDS orphanhood by decreasing adult mortality and population-level HIV transmission. Methods: We modeled two scenarios to measure the impact of adult ART use on the incidence of orphanhood in 10 sub-Saharan African countries, from 2009 to 2020. Demographic model data inputs were obtained from cohort studies, UNAIDS, UN Population Division, WHO and the US Census Bureau. Results: Compared to current rates of ART uptake, universal ART access averted 4.37 million more AIDS orphans by year 2020, including 3.15 million maternal, 1.89 million paternal and 0.75 million double orphans. The number of AIDS orphans averted was highest in South Africa (901.71 thousand) and Nigeria (839.01 thousand), and lowest in Zimbabwe (86.96 thousand) and Côte d'Ivoire (109.12 thousand). Conclusion: Universal ART use may significantly reduce orphanhood in sub-Saharan Africa.
Music Lessons: The Role of Music in Empathy Education for Physicians
Creators: name: Rao, Abhijit
Publisher: name: The University of Texas at Austin
Year: 2020
Subjects: humanities
music
medical education
medicine

description: In response to increasing physician burnout and deteriorating patient relationships, medical educators are increasingly adopting humanities approaches to better equip future physicians to cope with healthcare challenges. However, music has not been widely considered as a tool to reach this end. This work reviews the literature to explore how music can be used to nurture various skills related to empathy, which include listening to a patient narrative, engaging with the illness experience, and dealing with ambiguity. This study reviews the physiological evidence of connections between music and empathy and reviews evidence that suggests that listening to and performing music can train doctors to listen better, deal with the complexity of illness, and prioritize patient needs. The understanding brought by this exploration can be used to develop curricula that teach medical students about the importance of humanism in patient care. This could lead to better clinical outcomes, lower student distress levels, and increased patient satisfaction.
Transcriptional Regulation of TMP21 by NFAT
Creators: name: Liu, Shengchun
name: Zhang, Si
name: Bromley-Brits, Kelley
name: Cai, Fang
name: Zhou, Weihui
name: Xia, Kun
name: Mittelholtz, Jill
name: Song, Weihong
Publisher: name: BioMed Central
Year: 2015

description: Background: TMP21 is a member of the p24 cargo protein family, which is involved in protein transport between the Golgi apparatus and ER. Alzheimer's Disease (AD) is the most common neurodegenerative disorder leading to dementia and deposition of amyloid β protein (Aβ) is the pathological feature of AD pathogenesis. Knockdown of TMP21 expression by siRNA causes a sharp increase in Aβ production; however the underlying mechanism by which TMP21 regulates Aβ generation is unknown, and human TMP21 gene expression regulation has not yet been studied. Results In this report we have cloned a 3.3-kb fragment upstream of the human TMP21 gene. The transcription start site (TSS) of the human TMP21 gene was identified. A series of nested deletions of the 5' flanking region of the human TMP21 gene were subcloned into the pGL3-basic luciferase reporter plasmid. We identified the -120 to +2 region as containing the minimal sequence necessary for TMP21 gene promoter activity. Gel shift assays revealed that the human TMP21 gene promoter contains NFAT response elements. Expression of NFAT increased TMP21 gene expression and inhibition of NFAT by siRNA reduced TMP21 gene expression. Conclusion NFAT plays a very important role in the regulation of human TMP21 gene expression. This study demonstrates that the human TMP21 gene expression is transcriptionally regulated by NFAT signaling.
ACHIEVING FOOD SECURITY IN BAHRAIN
Creators: name: Janahi, Rawan
Publisher: name: American University of Bahrain
Year: 2024
Subjects: classificationCode: 30
subject: Agricultural, veterinary and food sciences
classificationCode: 300607
subject: Food technology
classificationCode: 460901
subject: Business process management
classificationCode: 300605
subject: Food safety, traceability, certification and authenticity

description: This master's thesis explores strategies and solutions to attain food security in the Kingdom of Bahrain, a small island in the Arabian Gulf that encounters substantial obstacles in guaranteeing a reliable and sustainable food provision. The study is driven by three fundamental research inquiries: First, what are the primary causes that contribute to Bahrain's restricted food security? Second, which cutting- edge agricultural methods and technologies can be utilized to maximize food production in Bahrain's constrained land and water resources? Third, what role may public-private partnerships (PPPs) play in tackling Bahrain's food security challenges?The thesis conducts a comprehensive examination of the obstacles to achieving food security in Bahrain, encompassing the nation's geographical limitations, lack of water resources, and significant dependence on imported food.This study evaluates the capacity of developing agricultural methods, such as vertical farming, aquaponics, and hydroponics, to improve household food production while reducing resource consumption. In addition, the study examines how Public-Private Partnerships (PPPs) might effectively utilize the knowledge and resources of both the public and private sectors to address food security concerns.By conducting a thorough examination of existing literature and analyzing pertinent theories in business and management, the research has identified a number of effective techniques and interventions. The results suggest that a comprehensive strategy that integrates cutting-edge agricultural methods, technology advancements, and cooperative alliances is crucial for enhancing Bahrain's sustainable food security in the long run.The main suggestions are as follows: First, allocating resources and expanding vertical farming, aquaponics, and hydroponics to optimize food production in confined areas. Second, establishing collaborations between public and private sectors to utilize their respective strengths and resources in research, infrastructure development, and financial assistance. Third, enforcing policies and regulations that encourage environmentally friendly farming methods and decrease dependence on imported food.The thesis adds to the expanding pool of information on food security methods, specifically within the setting of island states that have limited resources. The results offer significant perspectives for policymakers, agricultural professionals, and stakeholders in Bahrain and other nations confronting comparable food security issues.
title: Foldy-wouthuysen transformation and its generalisations
title: The foldy-wouthuysen transformation and its generalisations
titleType: AlternativeTitle
Creators: name: Pate, Michael B.
Publisher: name: University of Edinburgh
Year: 1961
Subjects: subject: Foldy-Wouthuysen transformations
subject: Representations
subject: Positive and negative energy states
subject: Single-particle transformations
subject: Two-particle transformations

description: The purpose of this thesis is to survey the developments in the field opened up in 1950 by Foldy and Wouthuysen. The investigations to be discussed here have all been concerned with the derivation of certain transformations (which are now all known as Foldy-Wouthuysen transformations, after the original workers); these transformations yield new (though, of course unitarily equivalent) representations of the conventional one-particle theories, which have a special property: the positive and negative energy states remain separate under the application of all the relevant operators of the theory. The present survey is limited in several ways. Mo attempt has been made to include papers containing computational applications of the Foldy-Wouthuysen transformation; or papers which generalise the transformation to the case of field theory (of which there is only one, to the author’s knowledge). However, full references to these papers are given. The order of development in the present work is not wholly historical. The thesis has been put into two parts, A and B. Part A deals with single-particle transformations, part B with two-particle transformations. This involved splitting a paper by Eriksen which deals with both cases by the same method.
A general approach for hysteresis-free, operationally stable metal halide perovskite field-effect transistors.
Creators: name: Senanayak, Satyaprasad P
name: Abdi-Jalebi, Mojtaba
name: Kamboj, Varun S
name: Carey, Remington
name: Shivanna, Ravichandran
name: Tian, Tian
name: Schweicher, Guillaume
name: Wang, Junzhan
name: Giesbrecht, Nadja
name: Di Nuzzo, Daniele
name: Beere, Harvey E
name: Docampo, Pablo
name: Ritchie, David A
name: Fairen-Jimenez, David
name: Friend, Richard H
name: Sirringhaus, Henning
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Despite sustained research, application of lead halide perovskites in field-effect transistors (FETs) has substantial concerns in terms of operational instabilities and hysteresis effects which are linked to its ionic nature. Here, we investigate the mechanism behind these instabilities and demonstrate an effective route to suppress them to realize high-performance perovskite FETs with low hysteresis, high threshold voltage stability (ΔVt < 2 V over 10 hours of continuous operation), and high mobility values >1 cm2/V·s at room temperature. We show that multiple cation incorporation using strain-relieving cations like Cs and cations such as Rb, which act as passivation/crystallization modifying agents, is an effective strategy for reducing vacancy concentration and ion migration in perovskite FETs. Furthermore, we demonstrate that treatment of perovskite films with positive azeotrope solvents that act as Lewis bases (acids) enables a further reduction in defect density and substantial improvement in performance and stability of n-type (p-type) perovskite devices.
Parent-child relationship of directly measured physical activity
Creators: name: Fuemmeler, Bernard F.
name: Anderson, Cheryl B.
name: Mâsse, Louise C.
Publisher: name: BioMed Central
Year: 2016

description: Background: Studies on parent-child correlations of physical activity have been mixed. Few studies have examined concurrent temporal patterns of physical activity and sedentary behaviors in parents and children using direct measures. The purpose of this study was to examine parent-child activity correlations by gender, day of week, and time of day, using accelerometers - a method for direct assessment of physical activity. Methods: Accelerometers were used to assess physical activity and sedentary time in 45 fathers, 45 mothers and their children (23 boys, 22 girls, mean age 9.9 years) over the course of 4 days (Thursday - Sunday). Participants were instructed to wear accelerometers for 24 hours per day. Data from accelerometers were aggregated into waking hours on weekdays and weekends (6:00 am to midnight) and weekday after-school hours (3:00 - 7:00 pm). Results: Across the 4 days, the mean minutes per day of moderate-to-vigorous physical activity (MVPA) for fathers was 30.0 (s.d. = 17.3), for mothers was 30.1 (s.d. = 20.1) and for children was 145.47 (s.d. = 51.64). Mothers' and fathers' minutes of MVPA and minutes of sedentary time were positively correlated with child physical activity and sedentary time (all ps <.05, with the exception of mothers' and children's sedentary time on weekdays from 6 am to 12 am). Multivariate linear regression analyses resulted in significant effects between parents and children for MVPA across all time segments. For sedentary activity, significant associations were observed only between father and child on the weekend. Sedentary activity of parents and children were not related for other time segments. Models examining the associations of one or two parents with high levels of MVPA or sedentary time indicated a dose response increase in child activity relative to parent. Conclusions: Greater parental MVPA was associated with increased child MVPA. In addition, having two parents with higher levels of MVPA was associated with greater levels of activity in children. Sedentary time in children was not as strongly correlated with that of their parents. Findings lend support to the notion that to increase childhood activity levels it may be fruitful to improve physical activity among parents.
QTL mapping in white spruce: gene maps and genomic regions underlying adaptive traits across pedigrees, years and environments
Creators: name: Pelgas, Betty
name: Bousquet, Jean
name: Meirmans, Patrick G
name: Ritland, Kermit
name: Isabel, Nathalie
Publisher: name: BioMed Central
Year: 2016

description: Background: The genomic architecture of bud phenology and height growth remains poorly known in most forest trees. In non model species, QTL studies have shown limited application because most often QTL data could not be validated from one experiment to another. The aim of our study was to overcome this limitation by basing QTL detection on the construction of genetic maps highly-enriched in gene markers, and by assessing QTLs across pedigrees, years, and environments. Results: Four saturated individual linkage maps representing two unrelated mapping populations of 260 and 500 clonally replicated progeny were assembled from 471 to 570 markers, including from 283 to 451 gene SNPs obtained using a multiplexed genotyping assay. Thence, a composite linkage map was assembled with 836 gene markers. For individual linkage maps, a total of 33 distinct quantitative trait loci (QTLs) were observed for bud flush, 52 for bud set, and 52 for height growth. For the composite map, the corresponding numbers of QTL clusters were 11, 13, and 10. About 20% of QTLs were replicated between the two mapping populations and nearly 50% revealed spatial and/or temporal stability. Three to four occurrences of overlapping QTLs between characters were noted, indicating regions with potential pleiotropic effects. Moreover, some of the genes involved in the QTLs were also underlined by recent genome scans or expression profile studies. Overall, the proportion of phenotypic variance explained by each QTL ranged from 3.0 to 16.4% for bud flush, from 2.7 to 22.2% for bud set, and from 2.5 to 10.5% for height growth. Up to 70% of the total character variance could be accounted for by QTLs for bud flush or bud set, and up to 59% for height growth. Conclusions: This study provides a basic understanding of the genomic architecture related to bud flush, bud set, and height growth in a conifer species, and a useful indicator to compare with Angiosperms. It will serve as a basic reference to functional and association genetic studies of adaptation and growth in Picea taxa. The putative QTNs identified will be tested for associations in natural populations, with potential applications in molecular breeding and gene conservation programs. QTLs mapping consistently across years and environments could also be the most important targets for breeding, because they represent genomic regions that may be least affected by G × E interactions.
title: Επιπτώσεις της κλιματικής αλλαγής στην εξάπλωση δασικών πυρκαγιών. Μελέτη περιπτώσεων σε ορεινή περιοχή του νομού Χανίων
title: Impacts of climate change on the spread of wild fires. A case study in a mountainous region of the prefecture of Chania
Creators: name: Βαρδουλακης Ευτυχιος-Δημητριος
Publisher: name: Technical University of Crete
Year: 2024

description: Η παρούσα εργασία επικεντρώνεται στη διερεύνηση του πώς η κλιματική κρίση επηρεάζει τη συχνότητα και την ένταση των δασικών πυρκαγιών. Χρησιμοποιώντας το πρόγραμμα FLAMMAP, προσομοιώθηκαν οι πυρκαγιές στις περιοχές "Σκλαβοπούλα" και "Κακοδίκι" με βάση τα υπάρχοντα μετεωρολογικά δεδομένα και τη διαχείριση της καύσιμης ύλης, καθώς και υπό διαφορετικά σενάρια αύξησης της θερμοκρασίας. Στόχος ήταν να αποτυπωθεί η επίδραση της κλιματικής αλλαγής στην εξάπλωση των πυρκαγιών, ειδικότερα στις περιοχές αυτές, οι οποίες είναι ευάλωτες λόγω της τοπογραφίας και των ιδιαίτερων μετεωρολογικών συνθηκών.
description: This paper focuses on investigating how the climate crisis affects the frequency and intensity of forest fires. Using the FLAMMAP program, fires were simulated in the "Sklavopoula" and "Kakodiki" areas based on existing meteorological data and fuel management, as well as under different temperature increase scenarios. The aim was to capture the effect of climate change on the spread of fires, especially in these areas, which are vulnerable due to the topography and special weather conditions.
Deliverable 8.4: Project website release
Creators: name: Iglesias Losada, Carlos
name: Eugenia Cornide, Maria
Publisher: name: Zenodo
Year: 2024

description: The "D8.4 Project Website Release" document for the HEREDITARY project details the creation and functionality of the project’s website, aimed at facilitating dissemination and communication of the project's objectives and achievements. As a key component of the project's communication strategy, the website serves as a central hub for information, accessible to both the general public and experts in the field.

Structured using WordPress and the DIVI Builder Pro editor, the website includes sections such as project overview, objectives, partners, use cases, resources, news, events, and contact information. It is designed to be responsive, ensuring optimal viewing on desktops, tablets, and smartphones.

The website is managed by FEUGA, the lead partner responsible for its construction and maintenance. It features frequent updates with new content including publications, deliverables, promotional materials, news, and events. This ensures continuous engagement with stakeholders and the wider public, fostering transparency and accessibility of the project's progress and outcomes.

To measure the website’s effectiveness, Google Analytics is used to track and evaluate visitor metrics, providing insights into user engagement and the most popular sections of the site.
Clinical utility and cost modelling of the phi test to triage referrals into image-based diagnostic services for suspected prostate cancer: the PRIM (Phi to RefIne Mri) study.
Creators: name: Kim, Lois
name: Boxall, Nicholas
name: George, Anne
name: Burling, Keith
name: Acher, Pete
name: Aning, Jonathan
name: McCracken, Stuart
name: Page, Toby
name: Gnanapragasam, Vincent J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Biopsy
prostate cancer
Mpmri
Prostate Health Index (Phi)
Cambridge Prognostic Groups

description: BACKGROUND:The clinical pathway to detect and diagnose prostate cancer has been revolutionised by the use of multiparametric MRI (mpMRI pre-biopsy). mpMRI however remains a resource-intensive test and is highly operator dependent with variable effectiveness with regard to its negative predictive value. Here we tested the use of the phi assay in standard clinical practice to pre-select men at the highest risk of harbouring significant cancer and hence refine the use of mpMRI and biopsies. METHODS:A prospective five-centre study recruited men being investigated through an mpMRI-based prostate cancer diagnostic pathway. Test statistics for PSA, PSA density (PSAd) and phi were assessed for detecting significant cancers using 2 definitions: ≥ Grade Group (GG2) and ≥ Cambridge Prognostic Groups (CPG) 3. Cost modelling and decision curve analysis (DCA) was simultaneously performed. RESULTS:A total of 545 men were recruited and studied with a median age, PSA and phi of 66 years, 8.0 ng/ml and 44 respectively. Overall, ≥ GG2 and ≥ CPG3 cancer detection rates were 64% (349/545), 47% (256/545) and 32% (174/545) respectively. There was no difference across centres for patient demographics or cancer detection rates. The overall area under the curve (AUC) for predicting ≥ GG2 cancers was 0.70 for PSA and 0.82 for phi. AUCs for ≥ CPG3 cancers were 0.81 and 0.87 for PSA and phi respectively. AUC values for phi did not differ between centres suggesting reliability of the test in different diagnostic settings. Pre-referral phi cut-offs between 20 and 30 had NPVs of 0.85-0.90 for ≥ GG2 cancers and 0.94-1.0 for ≥ CPG3 cancers. A strategy of mpMRI in all and biopsy only positive lesions reduced unnecessary biopsies by 35% but missed 9% of ≥ GG2 and 5% of ≥ CPG3 cancers. Using PH ≥ 30 to rule out referrals missed 8% and 5% of ≥ GG2 and ≥ CPG3 cancers (and reduced unnecessary biopsies by 40%). This was achieved however with 25% fewer mpMRI. Pathways incorporating PSAd missed fewer cancers but necessitated more unnecessary biopsies. The phi strategy had the lowest mean costs with DCA demonstrating net clinical benefit over a range of thresholds. CONCLUSION:phi as a triaging test may be an effective way to reduce mpMRI and biopsies without compromising detection of significant prostate cancers.
KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors.
Creators: name: Alicata, Claudia
name: Ashouri, Elham
name: Nemat-Gorgani, Neda
name: Guethlein, Lisbeth A
name: Marin, Wesley M
name: Tao, Sudan
name: Moretta, Lorenzo
name: Hollenbach, Jill A
name: Trowsdale, John
name: Traherne, James A
name: Ghaderi, Abbas
name: Parham, Peter
name: Norman, Paul J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: NK cells
Kir
Hla Class I
Immune Diversity
Iranian Populations

description: Natural killer (NK) cells are innate lymphocytes that eliminate infected and transformed cells. They discriminate healthy from diseased tissue through killer cell Ig-like receptor (KIR) recognition of HLA class I ligands. Directly impacting NK cell function, KIR polymorphism associates with infection control and multiple autoimmune and pregnancy syndromes. Here we analyze KIR diversity of 241 individuals from five groups of Iranians. These five populations represent Baloch, Kurd, and Lur, together comprising 15% of the ethnically diverse Iranian population. We identified 159 KIR alleles, including 11 not previously characterized. We also identified 170 centromeric and 94 telomeric haplotypes, and 15 different KIR haplotypes carrying either a deletion or duplication encompassing one or more complete KIR genes. As expected, comparing our data with those representing major worldwide populations revealed the greatest similarity between Iranians and Europeans. Despite this similarity we observed higher frequencies of KIR3DL1 * 001 in Iran than any other population, and the highest frequency of HLA-B*51, a Bw4-containing allotype that acts as a strong educator of KIR3DL1 * 001 + NK cells. Compared to Europeans, the Iranians we studied also have a reduced frequency of 3DL1 * 004, which encodes an allotype that is not expressed at the NK cell surface. Concurrent with the resulting high frequency of strong viable interactions between inhibitory KIR and polymorphic HLA class I, the majority of KIR-A haplotypes characterized do not express a functional activating receptor. By contrast, the most frequent KIR-B haplotype in Iran expresses only one functional inhibitory KIR and the maximum number of activating KIR. This first complete, high-resolution, characterization of the KIR locus of Iranians will form a valuable reference for future clinical and population studies.
Comparative analysis of habitat structure and macroinvertebrate assemblages in headwater streams of Odzi sub-catchment, Chimanimani District, Zimbabwe, post Cyclone Idai-induced flooding
Creators: name: Mamvura, Brian
name: Mwedzi, Tongayi
name: Utete, Beaven
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Flooding results in short and long-term modifications of aquatic ecosystem structure and biodiversity. Cyclone Idai, which ravaged through Zimbabwe in 2019, had devastating consequences on aquatic ecosystems. However, the extent of habitat modification and consequent biodiversity shifts are unknown. This study focuses on the comparative analysis of (i) habitat structure and (ii) macroinvertebrate assemblages in headwater streams of the Odzi sub-catchment, Chimanimani District, Zimbabwe, specifically examining the conditions post-Cyclone Idai-induced flooding. Field sampling was conducted in the dry season (September−November) 2019 and wet season (January−March) 2020. Headwater streams of the Murare (first order), Umvumvumvu (first and second order) and Nyanyadzi (first and second order) rivers were sampled. Habitat assessment was done following the Benthic Macroinvertebrate Monitoring Protocol Implementation Plan. Selected water variables were measured using appropriate probes. Macroinvertebrate assemblage data were collected using the South African Scoring System (SASS 5) protocol. Spatiotemporal variations in water quality, habitat structure and macroinvertebrate metrics were assessed using two-way ANOVA, ANOSIM and SIMPER. Significant spatiotemporal heterogeneity (p < 0.05) was detected in temperature, turbidity, conductivity and total dissolved solids, velocity and depth regimes, channel flow status, sediment deposition, channel alteration and frequency of riffles for the three rivers. Habitat quality ascending hierarchical order was: Umvumvumvu > Murare > Nyanyadzi after Cyclone Idai induced flooding. The highest macroinvertebrate composition diversity was detected in Murare River, the least flood-affected stream. The largest dissimilarity (ANOSIM, 75.3%) was between the Umvumvumvu and Nyanyadzi rivers. Macroinvertebrate community structure differed significantly because of species uniqueness and heterogenous tolerance to changes in environmental conditions after flooding. Flooding intensity and duration induces dissimilar environmental tolerances and persistent macroinvertebrates communities in lotic systems across local catchment scales. Long-term assessment of water quality impairment, resilient functional feeder groups and rifflescale physical habitat structure are imperative for optimised micro-scale conservation of macroinvertebrates in headwater streams prone to flash flooding.
A review of global surveillance on the muscle strengthening and balance elements of physical activity recommendations.
Creators: name: Milton, Karen
name: Varela, Andrea Ramirez
name: Strain, Tessa
name: Cavill, Nick
name: Foster, Charlie
name: Mutrie, Nanette
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: Surveillance
Balance
Strength
Physical Activity
Gopa

description: Introduction:Despite the importance of muscle strengthening and balance activities for health, these elements of the physical activity recommendations are often omitted from communication campaigns and national surveillance systems. This paper reviews national physical activity surveillance systems to determine which tools assess muscle strengthening and balance activities. Methods:We reviewed each tool that was used to inform the Global Observatory for Physical Activity (GoPA) country card prevalence estimates. Results:Of the 139 countries with GoPA country cards, 21 countries reported having no physical activity prevalence data. The prevalence estimates for 74 countries came from the World Health Organization 2014 Global Status Report on Non-Communicable Diseases. For the remaining 44 countries, a range of national and international surveys were used. A limited number of tools sought to assess muscle strengthening activities, and even fewer assessed balance and coordination activities. Discussion:Several issues arise from this review, including the need to: verify the strength of the evidence to inform whether muscle strength and balance should be given equal prominence to the aerobic recommendation; establish which activities count towards different aspects of the guidelines; and confirm whether the muscle strengthening and balance components of the guidelines are 'in addition' to the aerobic component.
Open Access Journals Support in Canada
Creators: name: Morrison, Heather
Publisher: name: The University of British Columbia
Year: 2016

description: The purpose of this research was twofold: to establish data indicating the current extent of support for open access publishing at Canadian university presses and libraries, and to identify economic models for further transition most likely to enjoy broad-based support. This research builds on an ARL study of journal hosting support by ARL member libraries, a qualitative investigation of open access publishing in Canada conducted by Kathleen Shearer, and models for transition developed by a number of initiatives, such as the Sponsoring Consortium for Open Access Particle Physics Publishing (SCOAP3) and the Stanford Encyclopedia of Philosophy.
A NEW SUBSPECIES OF DORCADION (CRIBRIDORCADION) TALYSCHENSE GANGLBAUER, 1884 FROM IRAN (COLEOPTERA, CERAMBYCIDAE)
Creators: name: Lazarev, M.A.
Publisher: name: Гуманитарное пространство
Year: 2017
Subjects: COLEOPTERA
CERAMBYCIDAE
DORCADIONINI
DORCADION
TAXONOMY
NEW SUBSPECIES
IRAN
AZERBAIJAN

description: Dorcadion ( Cribridorcadion ) talyschense sabalanum ssp. n. is described from North Iran, Ardebil province, SE slope of Sabalan Mt.
Hylotelephium telephium (L) H. Ohba leaves juice improves herpetic lesions: new findings from in vitro investigations
Creators: name: Arvia, Rosaria
name: Biagi, Marco
name: Baini, Giulia
name: Cappellucci, Giorgio
name: Governa, Paolo
name: Balatri, Sergio
name: Zakrzewska, Krystyna
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: The efficacy of Hylotelephium telephium (L.) H. Ohba (better known with its botanical synonym Sedum telephium L.) fresh leaf juice in the treatment of Herpes labialis wounds has been reported in traditional medicine in particular in Central regions of Italy; however, scientific insights are missing and the mechanism of action is not well understood. Aim of this study was to investigate the biological properties of S. telephium that underlie its ability to heal herpetic lesions. S. telephium fresh leaf juice (STJ) was analysed to obtain phytochemical information and tested in vitro to evaluate its antiviral activity against HSV-1 in Vero cells, then, according to computational predictions, immunomodulatory properties of STJ in human lympho-monocytes (PBMC), as well as its effect on cell viability in human keratinocytes (HaCaT cells), were also evaluated. Our results, at least in part, may explain the improvement of herpetic lesions empirically observed in patients treated with STJ: such improvement was not related to direct anti-viral effect of the juice but to its experimentally confirmed activity as cell viability booster and immunomodulatory agent.
Income inequities in end-of-life health care spending in British Columbia, Canada: A cross-sectional analysis, 2004-2006
Creators: name: Cunningham, Colleen M.
name: Hanley, Gillian E.
name: Morgan, Steve
Publisher: name: BioMed Central
Year: 2015

description: Background: This study aimed to measure the income-related inequalities and inequities - the inequalities that remain after accounting for differences in health need - in expenditure on fully publicly covered (hospital and ambulatory) and partially publicly covered (prescription drugs) services for those in their last year of life in the province of British Columbia (B.C.), Canada. We focused on a decedent population for three reasons: to minimize unmeasured need differences among our cohort and therefore isolate income effects; to explore inequities for a high-spending window of health care use; and, because previous studies have found conflicting relationships between income and decedent health care spending, to further quantify this relationship. Methods We used linked administrative databases to describe spending on health services by income for all 58,820 deaths of B.C. residents 65 and older from 2004 to 2006. Regression analyses examined the association between income and health care spending, adjusting for age, sex, health status, cause of death, and other relevant factors. We then used concentration indexes to measure both inequalities and inequities separately for three key types of services. Analyses were also run separately for men and women. Results On average, per capita expenditure on acute health care in the last year of life was $20,705 (CDN2006). In need-adjusted regression analyses, we found decedents in the highest income quintile had 11% lower hospital expenditures, 15% higher specialist expenditures and 23% higher prescription drug expenditures than decedents in the lowest income quintile. Concentration index analysis suggested that spending for all types of care was concentrated among those with higher income before adjusting for need. Need-adjusted equity results mirrored regression findings and suggested patterns of inequities that were more pronounced among male decedents than females. Conclusions Despite the universal health care system in B.C., we found patterns of inequity in spending by income in the last year of life, even for fully publicly covered services. These results, parallel to relationships between income and spending from previous studies of the B.C. population, suggest persistent income-related inequities in the health care Canadians receive throughout their lives.