cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
COMMENTS ON 2016 EUROPEAN GUIDELINES FOR THE MANAGEMENT OF ATRIAL FIBRILLATION NEW ASPECTS FOR PHYSICIANS.pdf
Creators: name: Galimzhanov, Akhmetzhan
Publisher: name: Figshare
Year: 2019
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Updated European guidelines for the management of atrial fibrillation were published on the 27 of August, 2016. This document is remarkable for new recommendations, especially about anticoagulation therapy. Key points of these guidelines and the possibility of their use in our country are described in the article.
Objective: to find out essential evidence-based key points of the 2016 guidelines and to investigate the possibility of their use in Kazakhstan. Materials and methods: To achieve these goals major differences between 2016, 2012, 2010 guidelines were analyzed. Then, to find out investigations, that support key points of the 2016 guidelines, a literature review in PubMed, MEDLINE, Web of Science, Scopus databases were carried out. The following key words was used: atrial fibrillation, European guidelines, anticoagulation, warfarin, novel antagonist oral anticoagulants. Results and conclusions: Aforementioned document is remarkable for inculcation of new essential recommendations, which can be listed in the next statements: 1. The prognostic value of the screening to determine silent atrial fibrillation has been highlighted. 2. EHRA symptom scale has been modified. 3. Changes in the CHA2 DS2-VASc scale using were introduced depend on gender. 4. Antiplatelet therapy is not recommended to prevent a stroke. 5. The role of novel anticoagulant has been strengthened in comparison with warfarin. 6. Edoxaban has been introduced as a recommended novel anticoagulant. 7. The possibility of the treatment with oral anticoagulant after intracranial haemorrhage has been scrutinized. 8. Algorithm about the use of oral anticoagulant after ischemic stroke has been developed. 9. The possibility of use double anticoagulant therapy instead of triple therapy among patients with atrial fibrillations after percutaneous coronary intervention has been proposed. 10. Statins are not recommended for primary prevention of atrial fibrillation. Overall, this evidence-based approach will enable to improve the management of atrial fibrillation in Kazakhstan.
Structure-Preserving Spectral Reflectance Estimation using Guided Filtering
Creators: name: Sippel, Frank
name: Seiler, Jürgen
name: Genser, Nils
name: Kaup, André
Publisher: name: arXiv
Year: 2022
Subjects: subject: Image and Video Processing (eess.IV)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Light spectra are a very important source of information for diverse classification problems, e.g., for discrimination of materials. To lower the cost for acquiring this information, multispectral cameras are used. Several techniques exist for estimating light spectra out of multispectral images by exploiting properties about the spectrum. Unfortunately, especially when capturing multispectral videos, the images are heavily affected by noise due to the nature of limited exposure times in videos. Therefore, models that explicitly try to lower the influence of noise on the reconstructed spectrum are highly desirable. Hence, a novel reconstruction algorithm is presented. This novel estimation method is based on the guided filtering technique which preserves basic structures, while using spatial information to reduce the influence of noise. The evaluation based on spectra of natural images reveals that this new technique yields better quantitative and subjective results in noisy scenarios than other state-of-the-art spatial reconstruction methods. Specifically, the proposed algorithm lowers the mean squared error and the spectral angle up to 46% and 35% in noisy scenarios, respectively. Furthermore, it is shown that the proposed reconstruction technique works out-of-the-box and does not need any calibration or training by reconstructing spectra from a real-world multispectral camera with nine channels.
НЕКОТОРЫЕ АСПЕКТЫ ОРГАНИЗАЦИИ САМОСТОЯТЕЛЬНОЙ РАБОТЫ СТУДЕНТОВ В КЛАССЕ ХОРОВОГО ДИРИЖИРОВАНИЯ В УСЛОВИЯХ БАКАЛАВРИАТА
Creators: name: ВОРОБЬЕВА С.А.
Publisher: name: Гуманитарные исследования Центральной России
Year: 2018
Subjects: ИНТОНИРОВАНИЕ
РИТМОИНТОНАЦИЯ
РИТМОИНТОНАЦИОННАЯ ЭНЕРГИЯ
МЕТРОРИТМИЧЕСКАЯ ОРГАНИЗАЦИЯ МУЗЫКАЛЬНОГО ПРОИЗВЕДЕНИЯ
СРЕДСТВА МУЗЫКАЛЬНОЙ ВЫРАЗИТЕЛЬНОСТИ
МУЗЫКАЛЬНАЯ ФОРМА
РИТМИЧЕСКОЕ РАЗВИТИЕ
ФАКТУРНОЕ РАЗВИТИЕ
КУЛЬМИНАЦИЯ
ИСПОЛНИТЕЛЬСКАЯ ИНТЕРПРЕТАЦИЯ

description: Настоящая статья посвящена некоторым аспектам работы над ритмоинтонацией, а ее цель осветить вопросы исполнительства, научить бакалавров распознавать в нотном тексте ключевые моменты, определяющие эмоционально-образное содержание музыкального произведения и исходя из этого интерпретировать его.
Trends in Bacterial Vaginosis Prevalence in a Cohort of U.S. Women with and at Risk for HIV
Creators: name: Murphy, K.
name: Dionne-Odom, J.
name: Golub, E.T.
name: Adimora, A.A.
name: Daubert, E.M.
name: Seidman, D.
name: Weber, K.M.
name: Kassaye, S.
name: Minkoff, H.
name: French, A.L.
name: Sheth, A.N.
name: Alcaide, M.L.
name: Massad, L.S.
name: Evans, C.T.
Publisher: name: Mary Ann Liebert Inc.
Year: 2022

description: Background: Women with human immunodeficiency virus (HIV) often have bacterial vaginosis (BV). The goal of this analysis was to assess how BV prevalence changed over time and across U.S. regions in enrollment cohorts of the Women's Interagency HIV Study. Methods: In a multisite study, BV was diagnosed retrospectively when pH and two of three other Amsel criteria were met. Prevalence was determined across four recruitment waves: 1994-5, 2001-2, 2011-2, and 2013-5. Generalized estimating equation multivariable logistic regression models assessed changes in visit prevalence across waves after controlling for HIV disease severity and other risks. Results: Among 4,790 women (3,539 with HIV and 1,251 without HIV), BV was diagnosed at 7,870 (12%) of 64,444 visits. Baseline prevalence across enrollment waves was 15.0%-19.2%, but declined in all cohorts, with prevalence in the initial cohort falling to 3.9% in the 1994-5 cohort after up to 21 years of continuous observation. Prevalence varied within U.S. regions. HIV status was not associated with BV. Conclusion: BV prevalence decreased with time in study. Prevalence varied across sites, but was not uniformly increased or decreased in any U.S. region. Clinical Trials.gov identifier: NCT00000797.
Spatio-spectral Image Reconstruction Using Non-local Filtering
Creators: name: Sippel, Frank
name: Seiler, Jürgen
name: Kaup, André
Publisher: name: arXiv
Year: 2022
Subjects: subject: Image and Video Processing (eess.IV)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: In many image processing tasks it occurs that pixels or blocks of pixels are missing or lost in only some channels. For example during defective transmissions of RGB images, it may happen that one or more blocks in one color channel are lost. Nearly all modern applications in image processing and transmission use at least three color channels, some of the applications employ even more bands, for example in the infrared and ultraviolet area of the light spectrum. Typically, only some pixels and blocks in a subset of color channels are distorted. Thus, other channels can be used to reconstruct the missing pixels, which is called spatio-spectral reconstruction. Current state-of-the-art methods purely rely on the local neighborhood, which works well for homogeneous regions. However, in high-frequency regions like edges or textures, these methods fail to properly model the relationship between color bands. Hence, this paper introduces non-local filtering for building a linear regression model that describes the inter-band relationship and is used to reconstruct the missing pixels. Our novel method is able to increase the PSNR on average by 2 dB and yields visually much more appealing images in high-frequency regions.
Integrase Inhibitors are Associated with Neuropsychiatric Symptoms in Women with HIV
Creators: name: Maki, P.M.
name: Sharma, A.
name: Xu, Y.
name: Gustafson, D.R.
name: Damron, A.L.
name: Spence, A.B.
name: Konkle-Parker, D.
name: Dastgheyb, R.
name: Fischl, M.A.
name: O’Halloran, J.A.
name: Li, Y.
name: Weber, K.M.
name: Rubin, L.H.
name: Williams, D.W.
name: Adimora, A.A.
name: Milam, J.
name: Ofotokun, I.
name: Fitzgerald, K.C.
Publisher: name: Springer
Year: 2022

description: Objective: Women with HIV(WWH) are more likely to discontinue/change antiretroviral therapy(ART) due to side effects including neuropsychiatric symptoms. Efavirenz and integrase strand transfer inhibitors(INSTIs) are particularly concerning. We focused on these ART agents and neuropsychiatric symptoms in previously developed subgroups of WWH that differed on key sociodemographic factors as well as longitudinal behavioral and clinical profiles. WWH from the Women’s Interagency HIV Study were included if they had ART data available, completed the Perceived Stress Scale-10 and PTSD Checklist-Civilian. Questionnaires were completed biannually beginning in 2008 through 2016. To examine ART-symptom associations, constrained continuation ratio model via penalized maximum likelihood were fit within 5 subgroups of WWH. Data from 1882 WWH contributed a total of 4598 observations. 353 women were previously defined as primarily having well-controlled HIV with vascular comorbidities, 463 with legacy effects(CD4 nadir < 250cells/mL), 274 aged ≤ 45 with hepatitis, 453 between 35–55 years, and 339 with poorly-controlled HIV/substance users. INSTIs, but not efavirenz, were associated with symptoms among key subgroups of WWH. Among those with HIV legacy effects, dolutegravir and elvitegravir were associated with greater stress/anxiety and avoidance symptoms(P’s < 0.01); dolutegravir was also associated with greater re-experiencing symptoms(P = 0.005). Elvitegravir related to greater re-experiencing and hyperarousal among women with well-controlled HIV with vascular comorbidities(P’s < 0.022). Raltegravir was associated with less hyperarousal, but only among women aged ≤ 45 years(P = 0.001). The adverse neuropsychiatric effects of INSTIs do not appear to be consistent across all WWH. Key characteristics (e.g., age, hepatitis positivity) may need consideration to fully weight the risk–benefit ratio of dolutegravir and elvitegravir in WWH.
ПРОБЛЕМЫ СОДЕРЖАНИЯ ШКОЛЬНОГО ИСТОРИЧЕСКОГО ОБРАЗОВАНИЯ В ТРУДАХ ОТЕЧЕСТВЕННЫХ ИСТОРИКОВ В 60-Е ГОДЫ XIX ВЕКА
Creators: name: КУЗЬМИНА Е.В.
Publisher: name: Гуманитарные исследования Центральной России
Year: 2018
Subjects: ШКОЛЬНЫЕ РЕФОРМЫ 60-Х ГОДОВ XIX ВЕКА
СОДЕРЖАНИЕ ШКОЛЬНОГО ИСТОРИЧЕСКОГО ОБРАЗОВАНИЯ
ИСТОРИЯ КАК НАУКА И УЧЕБНЫЙ ПРЕДМЕТ
С.М. СОЛОВЬЁВ
М.М.СТАСЮЛЕВИЧ
В.Я. ШУЛЬГИН

description: В статье рассматривается участие отечественных историков в обсуждении проблем содержания школьного исторического образования в период реформ 60-х годов XIX века. Показан вклад С.М. Соловьёва, М.М.Стасюлевича, В.Я. Шульгина в обсуждение вопроса о соотношении истории как науки и учебного предмета. Учёные выступали за структурно целостный систематический курс истории в школе, построенный в соответствии с логикой науки, говорили о необходимости введения в его содержание исторических источников, предложили учебники, ставшие первым опытом школьной хрестоматии. Таким образом, были заложены основы для дальнейшей разработки принципа научности содержания школьного исторического образования.
Hyperspectral Image Reconstruction from Multispectral Images Using Non-Local Filtering
Creators: name: Sippel, Frank
name: Seiler, Jürgen
name: Kaup, André
Publisher: name: arXiv
Year: 2022
Subjects: subject: Image and Video Processing (eess.IV)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Using light spectra is an essential element in many applications, for example, in material classification. Often this information is acquired by using a hyperspectral camera. Unfortunately, these cameras have some major disadvantages like not being able to record videos. Therefore, multispectral cameras with wide-band filters are used, which are much cheaper and are often able to capture videos. However, using multispectral cameras requires an additional reconstruction step to yield spectral information. Usually, this reconstruction step has to be done in the presence of imaging noise, which degrades the reconstructed spectra severely. Typically, same or similar pixels are found across the image with the advantage of having independent noise. In contrast to state-of-the-art spectral reconstruction methods which only exploit neighboring pixels by block-based processing, this paper introduces non-local filtering in spectral reconstruction. First, a block-matching procedure finds similar non-local multispectral blocks. Thereafter, the hyperspectral pixels are reconstructed by filtering the matched multispectral pixels collaboratively using a reconstruction Wiener filter. The proposed novel procedure even works under very strong noise. The method is able to lower the spectral angle up to 18% and increase the peak signal-to-noise-ratio up to 1.1dB in noisy scenarios compared to state-of-the-art methods. Moreover, the visual results are much more appealing.
МИГРАЦИОННЫЙ ОПЫТ И ТРАВМЫ ИНДИВИДУАЛЬНОЙ ПАМЯТИ В АВТОБИОГРАФИЧЕСКИХ РАССКАЗАХ РУССКИХ НЕМЦЕВ В ФРГ: ОПЫТ СОЦИОЛОГИЧЕСКОГО ИССЛЕДОВАНИЯ
Creators: name: ЛИНЧЕНКО А.А.
Publisher: name: Гуманитарные исследования Центральной России
Year: 2018
Subjects: ИНДИВИДУАЛЬНАЯ ТРАВМА
КУЛЬТУРНАЯ ТРАВМА
МИГРАЦИЯ
ИДЕНТИЧНОСТЬ
АВТОБИОГРАФИЧЕСКАЯ ПАМЯТЬ

description: В статье представлены результаты социологического исследования особенностей репрезентации травматического опыта в различных типах автобиографического рассказа русских немцев в ФРГ. Исследование выявило зависимость артикуляции травматического опыта и культурного шока русскоязычных жителей Германии от особенностей их автобиографического рассказа. Выявлены явные и косвенные случаи присутствия травматического опыта и элементов культурного шока, связанных с наличием разрывов автобиографического времени. Подтвержден вывод о ключевом значении культурной памяти, внутренних структур сообществ мигрантов и институтов принимающего общества для процессов конструирования индивидуальных и культурных травм русских немцев.
Notes on the linearity defect and applications
Creators: name: Nguyen, Hop D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Commutative Algebra (math.AC)
subject: FOS: Mathematics

description: The linearity defect, introduced by Herzog and Iyengar, is a numerical measure for the complexity of minimal free resolutions. Employing a characterization of the linearity defect due to Şega, we study the behavior of linearity defect along short exact sequences. We point out two classes of short exact sequences involving Koszul modules, along which linearity defect behaves nicely. We also generalize the notion of Koszul filtrations from the graded case to the local setting. Among the applications, we prove that if $R\to S$ is a surjection of noetherian local rings such that $S$ is a Koszul $R$-module, and $N$ is a finitely generated $S$-module, then the linearity defect of $N$ as an $R$-module is the same as its linearity defect as an $S$-module. In particular, we confirm that specializations of absolutely Koszul algebras are again absolutely Koszul, answering positively a question due to Conca, Iyengar, Nguyen and Römer.
description: Final version with minor revisions, 22 pages
ЭКЗИСТЕНЦИАЛЬНОЕ ЗНАЧЕНИЕ МОРАЛЬНОЙ СОСТАВЛЯЮЩЕЙ ИСТОРИЧЕСКОЙ КУЛЬТУРЫ
Creators: name: ЖУКОВА С.П.
Publisher: name: Гуманитарные исследования Центральной России
Year: 2018
Subjects: ИСТОРИЧЕСКАЯ КУЛЬТУРА
МОРАЛЬНАЯ СОСТАВЛЯЮЩАЯ ИСТОРИЧЕСКОЙ КУЛЬТУРЫ
ЭКЗИСТЕНЦИАЛЬНО-НРАВСТВЕННАЯ РЕФЛЕКСИЯ
МОРАЛЬНО-ПСИХОЛОГИЧЕСКИЙ РЕГУЛЯТИВ
ПРИКЛАДНАЯ ЭТИКА

description: В статье утверждается необходимость определения моральной составляющей исторической культуры в рамках тенденции обращения к этике в социально-гуманитарных трудах по исторической культуре; использование различных интерпретаций прошлого в социокультурных практиках усиливает актуальность темы. В статье предпринимается попытка определить уровни моральной составляющей исторической культуры: экзистенциально-нравственной рефлексии, морально-психологической регуляции, прикладной этики; на основании этого анализа делается вывод о фундировании исторической культуры экзистенциально-нравственными смыслами.
title: Lou Andreas-Salomé: Friedrich Nietzsche in seinen Werken. Mit 2 Bildern und 3 facsimilirten Briefen Nietzsches. Wien: Verlag von Carl Konegen, 1894. – 6 Bl., 263 S.
Creators: name: Glatz, Uwe
Publisher: name: Thüringer Universitäts- und Landesbibliothek
Year: 2019
Subjects: subject: Friedrich Nietzsche
subject: 020
subject: 100

description: Thüringer Universitäts- und Landesbibliothek Jena - Objekt des Monats, vol. 10, 2019
Christsein lernen in gemeinsamer Praxis von Gruppen
Creators: name: Biesinger, Albert
name: Schreijäck, Thomas
name: Kauer, Helga
Publisher: name: Diakonia
Year: 1970

description: Diakonia, Bd. 17 Nr. 5 (1986): Diakonia, Band 17, Heft 5
ИМПЕРСКИЙ МИФ - "МЕТАУРОВЕНЬ" ПОЛИТИЧЕСКОЙ МИФОЛОГИИ
Creators: name: ИВАНОВ А.Г.
Publisher: name: Гуманитарные исследования Центральной России
Year: 2018
Subjects: ИМПЕРСКИЙ МИФ
"АРХАИЧЕСКИЙ" И "КОНЪЮНКТУРНЫЙ" УРОВНИ СОЦИАЛЬНОЙ МИФОЛОГИИ
СОВРЕМЕННЫЙ СОЦИАЛЬНЫЙ МИФ
ПОЛИТИЧЕСКАЯ МИФОЛОГИЯ
ИДЕОЛОГИЯ
ЛЕГИТИМНОСТЬ

description: В статье рассмотрены особенности имперского мифа, сочетающего в себе два уровня социальной мифологии «архаический» и «конъюнктурный», и отличающегося от обычного политического мифа потенциальной способностью продуцировать дополнительные смыслы, придавая общественным процессам новые измерения. Автор приходит к выводу, что в настоящее время социальный миф имеет больше шансов стать имперским в крупных государствах с доминированием традиционной или харизматической легитимности.
title: Ein Dürer-Fund in Luthers "Wider Hans Worst"
Creators: name: Ott, Joachim
Publisher: name: Thüringer Universitäts- und Landesbibliothek
Year: 2016
Subjects: subject: Albrecht Dürer
subject: 020
subject: 760

description: Thüringer Universitäts- und Landesbibliothek Jena - Objekt des Monats, vol. 10, 2016
Progenitor model of Cosmic Ray knee
Creators: name: Bijay, Biplab
name: Bhadra, Arunava
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Primary energy spectrum of cosmic rays exhibits a knee at about $3$ PeV where a change in the spectral index occurs. Despite many efforts the origin of such a feature of the spectrum is not satisfactorily solved yet. Here it is proposed that the steepening of the spectrum beyond the knee may be a consequence of mass distribution of progenitor of cosmic ray source. The proposed speculative model can account all the major observed features about cosmic rays without invoking any fine tuning to match flux or spectra at any energy point. The prediction of the proposed model regarding primary composition scenario beyond the knee is quite different from most of the prevailing models of the knee and thereby can be discriminated from precise experimental measurement of the primary composition.
description: 7 pages, the revised version accepted for publication in Res. Astron. Astrophys
Computing the Degenerate Ground Space of Gapped Spin Chains in Polynomial Time
Creators: name: Chubb, Christopher T.
name: Flammia, Steven T.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Given a gapped Hamiltonian of a spin chain, we give a polynomial-time algorithm for finding the degenerate ground space projector. The output is an orthonormal set of matrix product states that approximate the true ground space projector up to an inverse polynomial error in any Schatten norm, with a runtime exponential in the degeneracy. Our algorithm is an extension of the recent algorithm of Landau, Vazirani, and Vidick for the nondegenerate case, and it includes the recent improvements due to Huang. The main new idea is to incorporate the local distinguishability of ground states on the half-chain to ensure that the algorithm returns a complete set of global ground states.
description: 33 pages
Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells
Creators: name: Hanna, D.B.
name: Vallejo, J.
name: Lazar, J.M.
name: Kaplan, R.C.
name: Tracy, R.P.
name: Tien, P.C.
name: Hedrick, C.C.
name: Lanier, L.L.
name: Pattarabanjird, T.
name: Durant, C.P.
name: Adimora, A.A.
name: Alimadadi, A.
name: Ghosheh, Y.
name: Armstrong Suthahar, S.S.
name: McNamara, C.A.
name: Ley, K.
name: Suryawanshi, V.
name: Hodis, H.N.
name: Gulati, R.
name: Ofotokun, I.
name: Mack, W.J.
name: Landay, A.L.
name: Saigusa, R.
name: Roy, P.
name: Shemesh, A.
name: Heath, S.L.
name: Weber, K.M.
name: Ehinger, E.
Publisher: name: BioMed Central Ltd
Year: 2022

description: Background: Cryopreserved peripheral blood mononuclear cells (PBMCs) are frequently collected and provide disease- and treatment-relevant data in clinical studies. Here, we developed combined protein (40 antibodies) and transcript single-cell (sc)RNA sequencing (scRNA-seq) in PBMCs. Results: Among 31 participants in the Women’s Interagency HIV Study (WIHS), we sequenced 41,611 cells. Using Boolean gating followed by Seurat UMAPs (tool for visualizing high-dimensional data) and Louvain clustering, we identified 50 subsets among CD4+ T, CD8+ T, B, NK cells, and monocytes. This resolution was superior to flow cytometry, mass cytometry, or scRNA-seq without antibodies. Combined protein and transcript scRNA-seq allowed for the assessment of disease-related changes in transcriptomes and cell type proportions. As a proof-of-concept, we showed such differences between healthy and matched individuals living with HIV with and without cardiovascular disease. Conclusions: In conclusion, combined protein and transcript scRNA sequencing is a suitable and powerful method for clinical investigations using PBMCs.
TreeCop - Evaluating the Feasibility of Sentinel-2 Data forDrought Stress Detection in Urban Trees
Creators: name: Gerhards, Max
name: Buddenbaum, Henning
name: Friedrichs, Jessica
name: Lindner, Christian
name: Knospe, Frank
Publisher: name: Zenodo
Year: 2023

description: Poster at Living Planet Symposium 2022
A Patient Decision Aid (i.ARTs) to Facilitate Women's Choice Between Oral and Long-Acting Injectable Antiretroviral Treatment for HIV: Protocols for its Development and Randomized Controlled Pilot Trial
Creators: name: Pereyra, M.
name: Wilson, T.E.
name: Sheth, A.N.
name: Rana, A.
name: Tamraz, B.
name: Adimora, A.A.
name: Sosanya, O.
name: Shaffer, V.A.
name: Goparaju, L.
name: Philbin, M.M.
name: Alcaide, M.
name: Cohen, M.H.
name: Kerrigan, D.
name: Topper, E.F.
name: McCrimmon, T.
Publisher: name: JMIR Publications Inc.
Year: 2022

description: Background: Many women with HIV (WWH) have suboptimal adherence to oral antiretroviral therapy (ART) due to multilevel barriers to HIV care access and retention. A long-acting injectable (LAI) version of ART was approved by the US Food and Drug Administration in January 2021 and has the potential to overcome many of these barriers by eliminating the need for daily pill taking. However, it may not be optimal for all WWH. It is critical to develop tools that facilitate patient-provider shared decision making about oral versus LAI ART modalities to promote women's adherence and long-term HIV outcomes. Objective: This study will develop and pilot test a web-based patient decision aid called i.ART+support (i.ARTs). This decision aid aims to support shared decision making between WWH and their providers, and help women choose between oral and LAI HIV treatment. Methods: The study will occur in 3 phases. In phase 1, we will utilize a mixed methods approach to collect data from WWH and medical and social service providers to inform i.ARTs content. During phase 2, we will conduct focus groups with WWH and providers to refine i.ARTs content and develop the web-based decision aid. In phase 3, i.ARTs will be tested in a randomized controlled trial with 180 women in Miami, Florida, and assessed for feasibility, usability, and acceptability, as well as to evaluate the associations between receiving i.ARTs and viral suppression, ART pharmacy refills, and clinic attendance. Results: This study was funded in March 2021. Columbia University's IRB approved the study protocols (approval number IRB-AAAT5314). Protocols for phase 1 interviews have been developed and interviews with service providers started in September 2021. We will apply for Clinicaltrials.gov registration prior to phase 3, which is when our first participant will be enrolled in the randomized controlled trial. This is anticipated to occur in April 2023. Conclusions: This study is the first to develop a web-based patient decision aid to support WWH choices between oral and LAI ART. Its strengths include the incorporation of both patient and provider perspectives, a mixed methods design, and implementation in a real-world clinical setting.
Novel 2-phenoxypyrido[3,2-b]pyrazin-3(4H)-one derivatives as potent and selective aldose reductase inhibitors with antioxidant activity
Creators: name: Hao, Xin
name: Qi, Gang
name: Hongxing Ma
name: Changjin Zhu
name: Zhongfei Han
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: To develop multifunctional aldose reductase (AKR1B1) inhibitors for anti-diabetic complications, a novel series of 2-phenoxypyrido[3,2-b]pyrazin-3(4H)-one derivatives were designed and synthesised. Most of the derivatives were found to be potent and selective against AKR1B1, and 2-(7-chloro-2-(3,5-dihydroxyphenoxy)-3-oxopyrido[3,2-b]pyrazin-4(3H)-yl) acetic acid (4k) was the most active with an IC50 value of 0.023 µM. Moreover, it was encouraging to find that some derivatives showed strong antioxidant activity, and among them, the phenolic 3,5-dihydroxyl compound 4l with 7-bromo in the core structure was proved to be the most potent, even comparable to that of the well-known antioxidant Trolox. Thus the results suggested success in the construction of potent and selective AKR1B1 inhibitors with antioxidant activity.
title: Lucas Cranach der Jüngere (?): Pergamentminiatur "Gesetz und Gnade" von 1543
Creators: name: Ott, Joachim
Publisher: name: Thüringer Universitäts- und Landesbibliothek
Year: 2015
Subjects: subject: Lucas Cranach der Jüngere
subject: 020
subject: 700

description: Thüringer Universitäts- und Landesbibliothek Jena - Objekt des Monats, vol. 10, 2015
title: Lucas Cranach d. J.: Die Erniedrigung des Kaisers Barbarossa durch Papst Alexander III.
Creators: name: Mutschler, Thomas
Publisher: name: Thüringer Universitäts- und Landesbibliothek
Year: 2014
Subjects: subject: Lucas Cranach der Jüngere
subject: 020
subject: 943

description: Thüringer Universitäts- und Landesbibliothek Jena - Objekt des Monats, vol. 10, 2014
Of gardens, suburbs and the Parsi ‘middling sort’ : the case of the Dadar Parsi colony in colonial Bombay
Creators: name: Ghosh, Vahishtai Debashish
Publisher: name: The University of St Andrews
Year: 2022

description: This thesis is an exploration of the Dadar Parsi Colony, a middle-class ethnic enclave located in an area of colonial Bombay which emerged in the early 20th century. The thesis argues that the Dadar Parsi Colony arose as part of Bombay’s built environment due to the circumstances that were created by the 1896 plague. It shows that area was the outcome of the import of garden city planning principles into Bombay’s urban landscape. It also argues that the Colony is an example of a microcosm of middle-class Parsi life. It enumerates the ways in which the Parsis who resided within the space of the Colony negotiated with notions of class and colonial modernity in the city. Finally, the thesis demonstrates that the spatial character of the neighbourhood was characterised and constituted by the cultural endeavours and practices of middle-class Parsis in the public and private spheres.
title: Ein Kinderbuch unter Verschluss
Creators: name: Kurlanda, Katrin
Publisher: name: Thüringer Universitäts- und Landesbibliothek
Year: 2021
Subjects: subject: Kinderbuch
subject: 020
subject: 370

description: Thüringer Universitäts- und Landesbibliothek Jena - Objekt des Monats, vol. 11, 2021
Multisite prospective Liver Disease and Reproductive Ageing (LIVRA) study in US women living with and without HIV
Creators: name: Sharma, A.
name: Adimora, A.
name: Plankey, M.
name: Tien, P.C.
name: Konkle-Parker, D.
name: Price, J.
name: Fischl, M.
name: Kuniholm, M.H.
name: French, A.L.
name: Golub, E.T.
name: Ma, Y.
name: Ofotokun, I.
Publisher: name: NLM (Medline)
Year: 2022

description: PURPOSE: The Liver Disease and Reproductive Ageing (LIVRA) study leverages the infrastructure of the decades-long multicentre prospective Women's Interagency HIV Study (WIHS) to examine the contributions of HIV, hepatitis C virus (HCV) and ageing to liver disease progression in women. PARTICIPANTS: From 2013 to 2018, LIVRA enrolled 1576 participants (77 HCV-seropositive only, 248 HIV/HCV-seropositive, 868 HIV-seropositive only and 383 HIV/HCV-seronegative) who underwent vibration controlled transient elastography (VCTE). A VCTE quality assurance programme was established to ensure consistency and accuracy for longitudinal assessment of steatosis (fatty liver) via the controlled attenuation parameter (CAP) and fibrosis via liver stiffness (LS). Demographic, lifestyle factors, anthropometry, clinical and medication history, host genetics, immune markers and hormone levels were collected as part of the WIHS. FINDINGS TO DATE: At baseline, 737 of 1543 women with CAP measurements had steatosis (CAP ≥248 dB/m) and 375 of 1576 women with LS measurements had significant fibrosis (LS ≥7.1 kPa), yielding a prevalence of 48% and 24%, respectively. On multivariable analysis, waist circumference (WC) and insulin resistance were independently associated with higher CAP (17.8 dB/m per 10 cm (95% CI:16.2 to 19.5) and 1.2 dB/m per doubling (95% CI:0.8 to 1.6), respectively). By contrast, HIV/HCV seropositivity and HCV seropositivity alone were associated with less steatosis compared with HIV/HCV-seronegative women, although the latter did not reach statistical significance (-9.2 dB/m (95% CI:-18.2 to -0.3) and -10.4 dB/m (95% CI: -23.8 to 3.1), respectively). Factors independently associated with higher LS were age (4.4% per 10 years (95% CI: 0.4% to 8.4%)), WC (5.0% per 10 cm (95% CI: 3.3% to 6.6%)), CAP steatosis (0.6% per 10 dB/m (95% CI: 0.1% to 1.0%)), HIV/HCV seropositivity (33% (95% CI: 24% to 44%)) and HCV seropositivity alone (43% (95% CI: 28% to 60%)). Excluding scans that were invalid based on traditional criteria for unreliability did not affect the results. FUTURE PLANS: Enrolled women undergo VCTE at 3-year intervals unless LS is ≥9.5 kPa, indicating advanced fibrosis, in which case VCTE is performed annually. Participants also undergo VCTE every 6 months until 18 months after HCV treatment initiation. Analysis of the data collected will provide insights into the impact of ageing/ovarian function, host genetics, immune function and contemporary HIV and HCV treatments on liver disease progression.
Systematic review of implementation barriers and facilitators in suicide prevention interventions; PRISMA protocol
Creators: name: Kasal, Alexandr
Publisher: name: Figshare
Year: 2019
Subjects: subject: 160510 Public Policy
subject: FOS: Political science
subject: Health Care
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 160508 Health Policy

description: PRISMA protocol for systematic review of implementation barriers and facilitators in suicide prevention interventions. Including preliminary search strategy for Medline. Next step is consultation and refining the search strategy and adapting it for other databases including the Open Grey database with grey area literature.

Goal of the current review is to comprehensively describe the implementation barriers and facilitators of different suicide prevention interventions by means of the systematic literature review.
title: Zur Erinnerung an Emil Hübner (1834–1901) und Rudolf Hübner (1864–1945): Rudolf Hübner; Vorbemerkung zu den Erinnerungen seines Vaters Emil Hübner. Jena, 30. Mai 1935
Creators: name: Dathe, Uwe
Publisher: name: Thüringer Universitäts- und Landesbibliothek
Year: 2019
Subjects: subject: Nachlass
subject: 020
subject: 340
subject: 943

description: Thüringer Universitäts- und Landesbibliothek Jena - Objekt des Monats, vol. 11, 2019
CD8 T Cell Virus Inhibition Assay Protocol
Creators: name: Archin, N.
name: Adimora, A.A.
name: Weideman, A.M.
name: Xu, Y.
name: Roan, N.
name: Clutton, G.
name: Gay, C.
name: Kuruc, J.
name: Abad-Fernandez, M.
name: Mollan, K.R.
name: Kallon, S.
name: Goonetilleke, N.
name: Hudgens, M.G.
name: Warren, J.A.
name: Samir, S.
Publisher: name: Bio-protocol LLC
Year: 2022

description: The human immunodeficiency virus (HIV)-1 viral inhibition assay (VIA) measures CD8+ T cell-mediated inhibition of HIV replication in CD4+ T cells and is increasingly used for clinical testing of HIV vaccines and immunotherapies. Different VIAs that differ in length of CD8:CD4 T cell culture periods (6-13 days), purity of CD4 cultures [isolated CD4+ T cells or CD8+ depleted peripheral blood mononuclear cells (PBMCs)], HIV strains (laboratory strains, isolates, reporter viruses) and read-outs of virus inhibition (p24 ELISA, intracellular measurement of p24, luciferase reporter expression, and viral gag RNA) have been reported. Here, we describe multiple modifications to a 7-day VIA protocol, the most impactful being the introduction of independent replicate cultures for both HIV infected-CD4 (HIV-CD4) and HIV-CD4:CD8 T cell cultures. Virus inhibition was quantified using a ratio of weighted averages of p24+ cells in replicate cultures and the corresponding 95% confidence intervals. We identify methodological and analysis changes that could be incorporated into other protocols to improve assay reproducibility. We found that in people living with HIV (PLWH) on antiretroviral therapy (ART), CD8 T cell virus inhibition was largely stable over time, supporting the use of this assay and/or analysis methods to examine therapeutic interventions.
PRISMA protocol for systematic review
Creators: name: Kasal, Alexandr
Publisher: name: Figshare
Year: 2019
Subjects: subject: 160510 Public Policy
subject: FOS: Political science
subject: Health Care
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 160508 Health Policy

description: PRISMA protocol for systematic review of implementation barriers and facilitators in suicide prevention interventions. Including preliminary search strategy for Medline. Next step is consultation and refining the search strategy and adapting it for other databases including the Open Grey database with grey area literature.

Goal of the current review is to comprehensively describe the implementation barriers and facilitators of different suicide prevention interventions by means of the systematic literature review.
title: Ein Lehrbuch der römischen Feldvermesser
Creators: name: Ott, Joachim
Publisher: name: Thüringer Universitäts- und Landesbibliothek
Year: 2018
Subjects: subject: Handschrift
subject: 020
subject: 940

description: Thüringer Universitäts- und Landesbibliothek Jena - Objekt des Monats, vol. 11, 2018
Systematic review of implementation barriers in mental health and suicide prevention prevention interventions; PRISMA protocol
Creators: name: Kasal, Alexandr
Publisher: name: Figshare
Year: 2019
Subjects: subject: 160510 Public Policy
subject: FOS: Political science
subject: Health Care
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 160508 Health Policy

description: PRISMA protocol for systematic review of implementation barriers and facilitators in suicide prevention interventions. Including preliminary search strategy for Medline. Next step is consultation and refining the search strategy and adapting it for other databases including the Open Grey database with grey area literature.

Goal of the current review is to comprehensively describe the implementation barriers and facilitators of different suicide prevention interventions by means of the systematic literature review.
title: Zur Erinnerung an Felix Hausdorff (1868–1942) und den 9. November 1938: Brief von Felix Hausdorff an Franz Meyer. Bonn, 6. Dezember 1938
Creators: name: Dathe, Uwe
Publisher: name: Thüringer Universitäts- und Landesbibliothek
Year: 2017
Subjects: subject: 020

description: Thüringer Universitäts- und Landesbibliothek Jena - Objekt des Monats, vol. 11, 2017
Measurement of AGN dust extinction based on the near-infrared flux variability of WISE data
Creators: name: Mizukoshi, Shoichiro
name: Minezaki, Takeo
name: Tsunetsugu, Shoichi
name: Yoshida, Atsuhiro
name: Sameshima, Hiroaki
name: Kokubo, Mitsuru
name: Noda, Hirofumi
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the measurement of the line-of-sight extinction of the dusty torus for a large number of obscured active galactic nuclei (AGNs) based on the reddening of the colour of the variable flux component in near-infrared (NIR) wavelengths. We collected long-term monitoring data by $\textit{Wide-field Infrared Survey Explorer (WISE)}$ for 513 local AGNs catalogued by the $\mathit{Swift/}$BAT AGN Spectroscopic Survey (BASS) and found that the multi-epoch NIR flux data in two different bands (WISE $W1$ and $W2$) are tightly correlated for more than 90% of the targets. The flux variation gradient (FVG) in the $W1$ and $W2$ bands was derived by applying linear regression analysis, and we reported that those for unobscured AGNs fall in a relatively narrow range, whereas those for obscured AGNs are distributed in a redder and broader range. The AGN's line-of-sight dust extinction ($A_V$) is calculated using the amount of the reddening in the FVG and is compared with the neutral hydrogen column density ($N_{\rm{}H}$) of the BASS catalogue. We found that the $N_{\rm{}H}/A_V$ ratios of obscured AGNs are greater than those of the Galactic diffuse interstellar medium (ISM) and are distributed with a large scatter by at most two orders of magnitude. Furthermore, we found that the lower envelope of the $N_{\rm{}H}/A_V$ of obscured AGNs is comparable to the Galactic diffuse ISM. These properties of the $N_{\rm{}H}/A_V$ can be explained by increase in the $N_{\rm{}H}$ attributed to the dust-free gas clouds covering the line of sight in the broad-line region.
description: 11 pages, 7 figures, published in MNRAS
ENVIRONMENTAL IMPACT ASSESSMENT ON SHEAR STRENGTH CHARACTERISTICS OF SOIL
Creators: name: Khoso, Salim
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 401102
subject: Environmentally sustainable engineering
classificationCode: 400599
subject: Civil engineering not elsewhere classified
classificationCode: 400504
subject: Construction engineering
classificationCode: 400505
subject: Construction materials

description: Environmental factors can have a significant impact on the shear strength characteristics of soil. The ability of soil to withstand internal sliding is known as shear strength, and it is a crucial engineering characteristic. It is necessary to have a basic understanding of this aspect for stability analyses in geotechnical engineering, such as those involving foundations, cutting slopes, or earth dams. In this study, the shear strength parameters (c and Ф) of soil were examined by testing disturbed soil samples with different densities and water contents to mimic field conditions. The Digital Direct/Residual Shear apparatus was used to perform the shear strength test. The test results revealed that increasing soil density also increases its shear strength. Although the water content of the soil has a significant impact on its cohesiveness, it has no effect on its angle of internal friction.
Ethnoracial Disparities in SARS-CoV-2 Seroprevalence in a Large Cohort of Individuals in Central North Carolina from April to December 2020
Creators: name: Pope, C.
name: Newberry-Dillon, C.
name: Larremore, D.B.
name: Pugh, S.
name: Vanna, U.P.
name: Baric, R.S.
name: Fosdick, B.K.
name: Lopez, C.A.
name: de Silva, A.M.
name: Emch, M.
name: Cunningham, C.H.
name: Boyce, R.M.
name: Adimora, A.A.
name: Pruitt, K.
name: Amditis, C.
name: Wiethorn, C.
name: Delacruz, M.J.
name: Schmitz, J.L.
name: Juliano, J.J.
name: Guerra, Q.
name: Bhowmik, D.R.
name: Hou, Y.J.
name: Premkumar, L.
name: Aiello, A.E.
name: Markmann, A.J.
name: Goldstein, S.J.
name: Brandt, K.
name: Gearhart, M.
Publisher: name: American Society for Microbiology
Year: 2022

description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of deaths around the world within the past 2 years. Transmission within the United States has been heterogeneously distributed by geography and social factors with little data from North Carolina. Here, we describe results from a weekly cross-sectional study of 12,471 unique hospital remnant samples from 19 April to 26 December 2020 collected by four clinical sites within the University of North Carolina Health system, with a majority of samples from urban, outpatient populations in central North Carolina. We employed a Bayesian inference model to calculate SARS-CoV-2 spike protein immunoglobulin prevalence estimates and conditional odds ratios for seropositivity. Furthermore, we analyzed a subset of these seropositive samples for neutralizing antibodies. We observed an increase in seroprevalence from 2.9 (95% confidence interval [CI], 1.8 to 4.5) to 12.8 (95% CI, 10.6 to 15.2) over the course of the study. Latinx individuals had the highest odds ratio of SARS-CoV-2 exposure at 6.56 (95% CI, 4.66 to 9.44). Our findings aid in quantifying the degree of asymmetric SARS-CoV-2 exposure by ethnoracial grouping. We also find that 49% of a subset of seropositive individuals had detectable neutralizing antibodies, which was skewed toward those with recent respiratory infection symptoms.
Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening
Creators: name: Atatreh, Noor
name: Rawashdah, Sara Al
name: Shaikha S. Al Neyadi
name: Abuhamdah, Sawsan M.
name: Ghattas, Mohammad A.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Butyrylcholinesterase (BChE) plays an important role in the progression of the Alzheimer’s disease. In this study, we used a structure-based virtual screening (VS) approach to discover new BChE inhibitors. A ligand database was filtered and docked to the BChE protein using Glide program. The outcome from VS was filtered and the top ranked hits were thoroughly examined for their fitting into the protein active site. Consequently, the best 38 hits were selected for in vitro testing using Ellman’s method, and six of which showed inhibition activity for BChE. Interestingly, the most potent hit (Compound 4) exhibited inhibitory activity against the BChE enzyme in the low micromolar level with an IC50 value of 8.3 µM. Hits obtained from this work can act as a starting point for future SAR studies to discover new BChE inhibitors as anti-Alzheimer agents.
T-cell activation state differentially contributes to neuropsychiatric complications in women with HIV
Creators: name: Adimora, A.A.
name: Rubin, L.H.
name: Dastgheyb, R.M.
name: Adedimeji, A.
name: Wang, Y.
name: Xu, Y.
name: Landay, A.L.
name: Flores, B.R.
name: Gange, S.J.
name: Fischl, M.
name: Ofotokun, I.
name: Cohen, M.H.
name: Tien, P.C.
name: Williams, D.W.
name: Weiser, S.D.
name: Yu, D.
name: Peters, B.A.
name: Laumet, G.
name: Weber, K.M.
name: Merenstein, D.
name: Wilson, T.E.
name: Turan, B.
name: Turan, J.
Publisher: name: Elsevier Inc.
Year: 2022

description: Neuropsychiatric complications are common among women with HIV (WWH). The pathophysiological mechanisms underlying these complications are not fully known but likely driven in part by immune modulation. We examined associations between T-cell activation states which are required to mount an effective immune response (activation, co-stimulation/normal function, exhaustion, senescence) and neuropsychiatric complications in WWH. 369 WWH (78% HIV RNA undetectable/<20cp/mL) enrolled in the Women's Interagency HIV Study completed neuropsychological testing and measures of depression (Center for Epidemiological Studies Depression Scale-CES-D), self-reported stress levels (Perceived Stress Scale-10), and post-traumatic stress (PTSD Checklist-Civilian Scale). Multiparametric flow cytometry evaluated T-cell activation state. Partial least squares regressions were used to examine T-cell phenotypes and neuropsychiatric outcome associations after confounder adjustment. In the total sample and among virally suppressed (VS)-WWH, CD4+ T-cell exhaustion was associated with poorer learning and attention/working memory (P's < 0.05). In the total sample, CD4+ T-cell activation was associated with better attention/working memory and CD8+ T-cell co-stimulation and senescence was associated with poorer executive function (P's < 0.05). For mental health outcomes, in the total sample, CD4+ T-cell activation was associated with more perceived stress and CD4+ T-cell exhaustion was associated with less depressive symptoms (P's < 0.05). Among VS-WWH, CD4+ senescence was associated with less perceive stress and CD8+ T-cell co-stimulation and senescence was associated with higher depression (P's < 0.05). Together, results suggest the contribution of peripheral CD4+ and CD8+ T-cell activation status to neuropsychiatric complications in WWH.
PSSOH workshop: How to assemble Klimerko (in Serbian: "PSSOH radionica: Kako napraviti Klimerka")
Creators: name: Milošević, Željka Desiree
name: Stanić, Vanja
Publisher: name: Zenodo
Year: 2020
Subjects: workshop
air quality
IoT
open hardware
measurement

description: SRPSKI JEZIK Post-konferencijska PSSOH radionica na temu pravljena Klimerka je održana 31. oktobra 2020. godine na Univerzitetu u Beogradu - Elektrotehničkom fakultetu u labroatoriji 69. Zvanični naziv radionice na srpskom jeziku je "Kako napraviti Klimerka". Ova verzija sadrži najavu radionice. PSSOH 2020 konferencija je uključila dve post-konferencijske radionice koje su održane 31. oktobra 2020. godine: Radionica instaliranja Linuksa koju su pripremili N. Todorović, M. Pavlović, D. Petković Kako napraviti Klimerka koju su pripremili Ž. Milošević Desiree i V. Stanić ENGLISH LANGUAGE Post-conferece PSSOH workshop on how to assemble Klimerko was held on October 31, 2020 at the University of Belgrade - School of Electrical Engineering in laboratory 69. The workshop title in English is "How to assemble Klimerko". This version contains workshop announcement. PSSOH 2020 conference included two post-conference workshops held on October 31, 2020: Linux installation workshop by N. Todorović, M. Pavlović, D. Petković How to assemble Klimerko by Ž. Milošević Desiree i V. Stanić
description: Photo of the building of Technical faculties (where PSSOH 2019 will take place) presented in the document was taken by Assist. Prof. Miodrag Tasić, PhD from University of Belgrade - School of Electrical Engineering, Belgrade, Serbia.