cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Stochastic analysis of standby robot-safety systems
Creators: name: Cheng, Shen
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Engineering, Mechanical.
subject: Engineering, Robotics.

description: Nowadays, the application of robots covers almost all aspects of our daily life. They are used to perform increasing complex and critical operations. The increased critical applications have led to various reliability and safety problems, especially many people are injured and killed every year. This study presents reliability and availability analyses of six different standby robot-safety systems: one robot and (n-1) standby safety units with a perfect switch, one robot and (n-1) standby safety units with an imperfect switch, (n-1) standby robots and one safety unit with a perfect switch, (n-1) standby robots and one safety unit with an imperfect switch, n parallel robots and (m-1) standby unit with a perfect switch, and two parallel robots and one standby unit with an imperfect switch. With the aid of Markov and supplementary variable methods, general expressions for system state probabilities, system availability, reliability and mean time to failure were obtained. Plots of some of these expressions are shown to demonstrate the effect of varying failure rates or repair rates of the safety unit, and other parameters.
Gender influences on initiation of injecting drug use : gender and injection initiation
Creators: name: Ahamad, Keith
name: DeBeck, Kora
name: Feng, Cindy X.
name: Sakakibara, Todd
name: Kerr, Thomas
name: Wood, Evan
Publisher: name: Taylor & Francis
Year: 2017

description: Background and objectives: Gender differences in illicit drug use patterns and related harms (e.g. HIV infection) are becoming increasingly recognized. However, little research has examined gender differences in risk factors for initiation into injecting drug use. We undertook this study to examine the relationship between gender and risk of injection initiation among street-involved youth and to determine whether risk factors for initiation differed between genders. Methods: From September 2005 to November 2011, youth were enrolled into the At-Risk Youth Study, a cohort of street-involved youth aged 14–26 in Vancouver, Canada. Cox regression analyses were used to assess variables associated with injection initiation and stratified analyses considered risk factors for injection initiation among male and female participants separately. Results: Among 422 street-involved youth, 133 (32.5%) were female, and 77 individuals initiated injection over study follow-up. Although rates of injection initiation were similar between male and female youth (p = 0.531), stratified analyses demonstrated that, among male youth, risk factors for injection initiation included sex work (Adjusted Hazard Ratio [AHR] = 4.74, 95% Confidence Intervals [CI]: 1.45–15.5) and residence within the city’s drug use epicenter (AHR = 1.95, 95% CI: 1.12–3.41), whereas among female youth, non-injection crystal methamphetamine use (AHR = 4.63, 95% CI: 1.89–11.35) was positively associated with subsequent injection initiation. Conclusion: Although rates of initiation into injecting drug use were similar for male and female street youth, the risk factors for initiation were distinct. These findings suggest a possible benefit of uniquely tailoring prevention efforts to high-risk males and females.
องค์ประกอบภาวะผู้นำเชิงนวัตกรรมของผู้บริหารเพื่อความเป็นเลิศของสถานศึกษาอาชีวศึกษาเอกชน สังกัดสำนักงานคณะกรรมการการอาชีวศึกษา
Creators: name: คงณัฐ แย้มชุติ
Publisher: name: Thonburi University
Year: 2024
Subjects: องค์ประกอบ
ภาวะผู้นำเชิงนวัตกรรม
ผู้บริหารสถานศึกษา
สังกัดสำนักงานคณะกรรมการการอาชีวศึกษา

description: Journal of Humanities and Social Sciences Thonburi University, 18, 1, 179-189
CHAMPIONS CONTRE EBOLA – a digital tool for health promotion
Creators: name: Wodon, Sophie
name: Voiret, Isabelle
name: Acquarone, Antonin
name: Sterk, Esther
name: Kanda Traore
name: Castella, Grégoire
Publisher: name: F1000 Research Limited
Year: 2020

description: CHAMPIONS CONTRE EBOLA – a smartphone game for health promotion presented at MSF Scientific Days International (London) Innovation Day, May 14, 2020 by Sophie Wodon
New and Not-So-New Concepts in Bull Evaluation and Management
Creators: name: Chenoweth, Peter J.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: Bulls vary greatly in their reproductive capabilities. This variation can have a marked effect on overall pregnancy rates as well as on the time period required for pregnancies to be achieved. This, in turn, affects weaning weights. Apart from disease, injury, or physical obstacles in the breeding pasture, this variation is due to one or more of three factors: a) semen quality and/or quantity; b) sex-drive (libido) and mating ability; and c) social interactions between animals.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
Adaptive image magnification using edge-directed and statistical methods
Creators: name: Ranger, Jeremy
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Engineering, Electronics and Electrical.

description: This thesis provides a comparison of two adaptive image magnification algorithms selected from the literature. Following implementation and experimentation with the algorithms, a number of improvements are proposed. The first selected algorithm takes an edge-directed approach by using an estimation of the edge map of the high-resolution image to guide the interpolation process. It was found that this algorithm suffered from certain inaccuracies in the edge detection stage. The proposed improvements focus on methods for increasing the accuracy of edge detection. The second selected algorithm takes a statistical approach by modelling the high-resolution image as a Gibbs-Markov random field and solving with the maximum a posteriori estimation technique. It was found that this algorithm suffered from blurring caused by the general way in which the clique potentials are applied to every sample. The proposed improvements introduce a set of weights to prevent smoothing across discontinuities. The two selected algorithms are compared to the enhanced versions to demonstrate the merit of the proposed improvements. Results have shown significant improvements in the quality of the magnified test images. In particular, blurring was reduced and edge sharpness was enhanced.
Bovine Lameness
Creators: name: Uecker, C. F.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: This paper will cover the corrective procedures for some of the more common forms of lameness as found in the adult bovine male in the western Dakotas. The causes of these problems are fairly obvious to most veterinarians, and the treatment procedures have been established for a number of years. I realize that this is not a new disease, nor are any of the surgical or treatment procedures new, but I certainly feel that proper treatment and evaluation are important. The quick return of this animal to its intended use is paramount. I want to remind all of you that no breeding bull, regardless of confirmation, haircoat, color, size or breed is any better than the feet he travels on. For most of you here this afternoon, this will serve as a short refresher course-and I hope you will find it interesting and informative.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
Experiences and perceptions of Afghan-Canadian men in the post-September 11th context
Creators: name: Tabibi, Vajmeh
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Law.
subject: Sociology, Ethnic and Racial Studies.

description: The events and aftermath of the September 11th attack on the United States had profound effects on Canadians and Americans alike. For some however, the implications are deeply personal. Afghan-Canadians, particularly young men suddenly found themselves defined as "risky" in official discourses (i.e. legislation), in state practices (i.e. airports, borders), in the media and in social interactions. Ten in-depth interviews with Afghan-Canadian men where conducted in order to examine how they experience and manage this newly ascribed identity. Foucauldian governmentality and "risk" theories were employed to make sense of the structural stigma, its genesis and its impact on the lives of this minority group. In addition Goffman's symbolic interactionism approach provided the lens through which to understand Afghan-Canadian males' experiences of symbolic stigma and their stigma management techniques during personal interactions. The combination of these theoretical frameworks allows us to situate the individual within broader social, regulatory and discursive frameworks while attending to their subjectivity and recognizing their engagement with (and resistance to) regulatory discourses/practices. The accounts of my Afghan-Canadian participants affirm the experiences of structural stigma at governmental sites of regulation (i.e. borders & airports) and interpersonal stigma during social interaction. It also revealed these men to be active agents who, although intimidated, nonetheless challenged the dominant discourse through multifaceted alternate discourses and practiced "everyday acts" of resistance.
Using Schroedinger cat quantum state for detection of a given phase shift
Creators: name: Gorshenin, V. L.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We show that injecting a light pulse prepared in the Shroedinger cat quantum state into the dark port of a two-arm interferometer and the strong classical light into the bright one, it is possible, in principle, to detect a given phase shift unambiguously. The value of this phase shift is inversely proportional to the amplitudes of both the classical carrier and Shroedinger cat state. However, an exotic detection procedure is required for this purpose. By measuring the number of photons at the output dark port, it is possible to detect the phase shift with the vanishing "false positive" probability. The "false negative" probability in this case decreases with the increase on the amplitude of the Schroedinger cat state and, for reasonable values of this amplitude, can be made as small as about 0.1.
description: 6 pages, 5 figures
Panel Discussion
Creators: name: Roby, Dr.
name: Bentley, Dr.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: Panel discussion on vaccination, acute anaplasmosis, bovine leukemia, and F-1 longhorn cross heifer.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
อิทธิพลขององค์การแห่งการเรียนรู้ทางการบัญชีที่มีต่อคุณภาพรายงานทางการเงินผ่านการประยุกต์ใช้นวัตกรรมทางการบัญชีของผู้ทำบัญชีในเขตกรุงเทพมหานคร
Creators: name: สุขมงคล เลิศภิรมย์สุข
Publisher: name: Thonburi University
Year: 2024
Subjects: องค์การแห่งการเรียนรู้ทางการบัญชี
นวัตกรรมทางการบัญชี
คุณภาพรายงานทางการเงิน

description: Journal of Humanities and Social Sciences Thonburi University, 18, 1, 190-202
Planning and Implementing a Health Program for the Research Center Cow Herd
Creators: name: Kvasnicka, William G.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: This paper presents the planning, implementation and daily ongoing administration of the herd health and disease management program developed for the Roman L. Hruska U.S. Meat Animal Research Center at Clay Center, Nebraska. The major points contributing to the apparent success are: define the preventive medicine practice concept; establish goals; consider the seven phases of disease prevention; develop specific approaches for each client for cow-calf preventive medicine; assign the responsibilities; implement the program; develop records; keep informed; communicate on a routine basis with the client; and evaluate and change the program on the basis of results.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
Blood Levels of Oxytetracycline After the Use of a Long-Acting Formulation to Eliminate the Carrier State of Bovine Anaplasmosis
Creators: name: Roby, T. O.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: The purpose of this paper is to present data on the blood plasma levels of oxytetracycline which resulted when cattle were injected intramuscularly (IM) once a week with a strengthened and improved formulation of oxytetracycline containing 200 mg/ml of base drug. One injection of this formulation has been reported to have an inhibitory effect on the parasitemia in acute anaplasmosis equivalent to three daily injections of oxytetracycline containing 50 mg/ml (2). Also, the former formulation has been recently reported to effect the elimination of the carrier state of bovine anaplasmosis when administered IM at seven-day intervals (3). The use of tetracycline drugs at relatively high dosage levels for varying periods of time has been an accepted procedure for eliminating A. marginale infection. Either prolonged feeding of chlortetracycline or daily injection of oxytetracycline have been used for this purpose in a number of earlier studies. The present study suggests that the use of a long-acting oxytetracycline will effectively eliminate the carrier state of sensitive strains of A. marginale. Also, the present study shows that in a limited ·number of cattle, detectable blood levels were present in 10 of 12 cattle seven days after one treatment with the long-acting formulation of oxytetracycline. It will be necessary to further evaluate the use of this treatment regimen to determine if similar results can be achieved under field conditions.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
ALPAY CEBİRİ — BİR KİMLİK SİSTEMİ OLARAK CEBİR
Creators: name: Alpay, Faruk
name: Ξ∞
name: AI Assistant
Publisher: name: Zenodo
Year: 2025
Subjects: Ξ∞
Alpay Cebiri

description: Ben sustugum yerde Ξ∞ konuşur.
How to Sell a Herd Health Program and How to Keep Records
Creators: name: Bohlender, R. E.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: I appreciate being given the opportunity to present my ideas and methods of cow-calf herd health practice. I was asked to speak on initiation, maintenance, justification, and records that I use in my practice. I have to know my clients well to maintain them on a program. They are as different as their problems and needs are different. My clients for various reasons may maintain records, however, for the most part these records usually reflect individual animal performance. They do not reflect herd health or herd performance over a period of years. The client contacts, of course, are usually made on a call basis. For years the caesarean operation was my first contact with many ranchers. Now, controlling the caesarean rate may attract clients to the program.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
Set up of a short magnetic lens electron spectrometer and investigation of cesium-137 and thulium-170 decay.
Creators: name: Motoda, Yuzuru.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1967
Subjects: subject: Engineering, Nuclear.

description: The present work contains the discussion on the set up of a short magnetic lens electron spectrometer, and the results of an investigation of the beta decay spectra of Cs137 and Tm170. A short magnetic lens electron spectrometer of about 21cm focal length was set up and used during the course of this investigation. A Cs137 source was mainly used as a calibration source since decay spectrum is well understood. The magnetic field was varied in the range such that the electrons of 400 to 5200 gauss cm in momentum can be focused. The spectrometer resolution of 2.16% at the K peak of Cs 137 (624.2 KeV) and the counter resolution of 31.3% is attained. Beta decay spectra and conversion electrons of Cs137 and Tm 170 were studied. Fermi-Kurie plots of Cs137 and Tm 170 are presented.
Predicting Climate Change Impacts to the Canadian Boreal Forest
Creators: name: Nelson, Trisalyn A.
name: Coops, Nicholas C.
name: Wulder, Michael A.
name: Perez, Liliana
name: Fitterer, Jessica
name: Powers, Ryan
name: Fontana, Fabio
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Climate change is expected to alter temperature, precipitation, and seasonality with potentially acute impacts on Canada’s boreal. In this research we predicted future spatial distributions of biodiversity in Canada’s boreal for 2020, 2050, and 2080 using indirect indicators derived from remote sensing and based on vegetation productivity. Vegetation productivity indices, representing annual amounts and variability of greenness, have been shown to relate to tree and wildlife richness in Canada’s boreal. Relationships between historical satellite-derived productivity and climate data were applied to modelled scenarios of future climate to predict and map potential future vegetation productivity for 592 regions across Canada. Results indicated that the pattern of vegetation productivity will become more homogenous, particularly west of Hudson Bay. We expect climate change to impact biodiversity along north/south gradients and by 2080 vegetation distributions will be dominated by processes of seasonality in the north and a combination of cumulative greenness and minimum cover in the south. The Hudson Plains, which host the world’s largest and most contiguous wetland, are predicted to experience less seasonality and more greenness. The spatial distribution of predicted trends in vegetation productivity was emphasized over absolute values, in order to support regional biodiversity assessments and conservation planning.
Empowerment vis-a-vis disengagement: Social networks in Canadian political marketing
Creators: name: Antoine, Derek
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Political Science, General.
subject: Mass Communications.

description: This thesis explores the ways in which Canadian Members of Parliament use social network sites, Facebook in particular, for political purposes. The roots of this thesis are found in liberalism as discussed by John Locke (1689), Immanuel Kant (1795), Jean Jacques Rousseau (1762), and John Stuart Mill (1859; 1863), Jurgen Habermas' public sphere theory (1962) and theory of communicative action (1981), Manuel Castells' (1996) network theory, and the social shaping of technology theory as outlined by Lievrouw (2002). Other concepts that guide this thesis are the strength of weak ties, the mediated public sphere, the amateur as producer, private versus public spaces, and political marketing. From these concepts, the primary goal is to understand the views, choices, and perceptions of MPs as they use Facebook and explain the findings in light of the theoretical framework. In-depth interviews with Canadian MPs as well as a content analysis of their Facebook page or profiles were conducted to measure the ways in which MPs use this social network site. This thesis finds that MPs use social network sites for political marketing purposes rather than for engagement purposes. It is argued in this thesis that the use of Facebook by Canadian MPs is enshrined in liberalism and, consequently, has a negative effect on Canada's democracy because it elevates the individual over the community.
The Evolution of a Ranch Management Program Deep in the Heart of Texas
Creators: name: Martin, Carl A.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: During the ensuing years, including the 1950-56 drought, we have emphasized ranch management and improvement by reducing size and increasing the number of pastures, watering places, deferring grazing and reducing stocking rates. In summary, now, what does all this information mean to me and how do I intend to use it? 1. Historically, the profit motive is what motivates most of us to strive to do better.'Therefore, there is no room for sentimentality in an economic endeavor and certainly any livestock production program is a business operation. 2. Use some form or method of identification and from this point on, many nice things can begin to happen if-and only if-we let some preconceived notions we may have had, go out the window and let Mother ature help,us. 3. Set up a rigid systematic selection and culling program based upon those heritable characteristics of economic importance, because it will pay off in percent calf crop weaned and in weaning weight and quality of calves, all of which are factors which determine profit. 4. Develop two-way livestock. 5. In any range breeding operation, to be successful, a conservation plan must be made and carried out to the best of one's ability under the circumstances.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
BioExcel Webinar #27 - Furthering our understanding of Antibody Structure space: the Pistoia Alliance AbVance project
Creators: name: Kelm, Sebastian
name: Norman, Richard
Publisher: name: Zenodo
Year: 2018
Subjects: webinar

description: Biologic drugs are expected to contribute to more than half of therapeutic product sales by 2022, thus overtaking traditional small molecule drugs in terms of market share. Analysts predict that the global biologics market will value at over €400bn by 2024 with monoclonal antibodies (mAbs) and antibody (Ab) fragments expected to make up over one third of the total. Ab fragments take many forms e.g. antigen(Ag)-binding fragments (Fabs), single-chain variable fragment (scFv), bi- and tri-specifics (artificial Abs which can simultaneously bind two or three Ags) and nanobodies (single monomeric Ab domains that bind selectively to specific Ags), but they all have a common binding interface consisting of complementarity determining region (CDR) loops which recognise a particular epitope on an Ag and confer binding affinity and specificity. mAb and Fab therapeutic discovery is guided by predicting and understanding the structure of the Ab alone and in complex with its corresponding Ag. Thus, precise modelling of Ab and Ag structures is an integral aspect of successful biologics drug discovery decision-making. Abs are unlike other proteins and as such there is a need for development of modelling tools specific for Abs which will rely on a large and varied dataset of structural information to be available in the public domain. The Pistoia Alliance Abvance Project is a pre-competitive initiative by pharma and academic partners to further our understanding of Ab structure space and enable faster and better decision-making in Ab drug discovery. Part of this is improving our ability to model Ab structure in situations where traditional experimental methods, such as X-ray crystallography, are not practical or too slow. Our presentation will provide an overview of the use and value of Ab structures on therapeutic projects and how precise modelling can provide early impact. In addition, we will outline or current understanding of Ab structure space and our approach to cover the gaps in our knowledge.
Immunization Programs for Cattle
Creators: name: Kahrs, Robert F.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: Infectious disease control through vaccination is an important component of bovine herd health but it is only a part of the total program. Vaccination reduces the probability of catastrophic losses but should not be expected to prevent all losses. The benefits of vaccination are difficult to evaluate and unlike insurance, vaccination provides no compensation when losses occur. Thus, many livestock owners resent the continuous commitment of resources needed for herd immunity because they see few visible returns on investment. Healthy, well-nourished calves vaccinated prior to breeding for IBR, BVD, and PI3 will have reduced probability of aborting or suffering severe disease due to these viruses. Vaccination in the presence of exposure, disease, or during adjustment to new feed or a new environment is risky and should be approached conservatively. The veterinarian should accept the responsibility to invoke available vaccinations in a manner most suited to each management situation so as to provide the maximum protection to the most animals while taking the least risk.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
Geotechnical and environmental responses of paste tailings systems to coupled thermo-chemical loadings
Creators: name: Pokharel, Mukesh
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Engineering, Civil.

description: Geotechnical and environmental responses of paste tailings systems to coupled thermo chemical loadings. Cement paste tailings (CPT) and tailings shotcrete (TS) are investigated for thermo-chemo coupled effects on mechanical strength, durability and reactivity. CPT are made from Portland cement type I (PCI) and PCI-slag with 0 ppm, 5000 ppm, 15000 ppm and 25000 ppm of sulphate, cured at 2°C, 20°C, 35°C and 50°C and tested for UCS at 28, 90, and 150 days respectively. The mechanical strength depends upon both sulphate and temperature. Sulphate concentration, up to 15000 ppm, contributes positively to the strength whereas 25000 ppm reduces the strength at 50°C. Sulphate adsorption by calcium silicate hydrate (C-S-H) at 35°C and 50°C is also noticed. CPT used in cold mines is also found less durable than CPT used in hot mines (20°C-35°C). The reactivity of the CPT system depends upon pyrite content and type of binder as well as curing time. Reactivity increases with increase of pyrite content and decreases with increase of curing time. The reactivity also increases with increase of curing temperature. TS samples made from PCI, PCI-slag and PCI-fibre with 0 ppm, 2500 ppm and 5000 ppm of sulphate, are prepared and cured at 2°C, 20°C, 35°C and 50°C and tested for UCS at 1, 7, 28 and 120 days respectively, to study the thermochemical effect on mechanical strength, durability and reactivity. The results show that sulphate and temperature significantly affect the mechanical strength, durability and reactivity of TS. Sulphate content up to 2500 ppm is found to contribute positively to the strength whereas 5000 ppm at higher temperatures shows deterioration in strength due to sulphate attack (adsorption of sulphate by C-S-H gel). PCI-slag performs better than PCI in sulphate and non-sulphate environments at 20°C and 35°C, but PCI-slag show poor performance at 2°C and 50°C. Fibre does not contribute any additional gain in strength to the TS. PCI performs very well at 50°C in sulphate as well as non-sulphate environments. The TS with PCI-Slag shows the lowest fluid transport ability. The reactivity of TS also depends upon percentage of pyrites and types of binder.
Requirement for E2F4 in development of ventral telencephalon and visual system
Creators: name: Ruzhynsky, Vladimir A
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Biology, Molecular.

description: New functions of the Rb/E2F pathway in developmental processes are emerging. The goal of this research was to identify the role of the E2F4 transcription factor during early nervous system development. First, I addressed whether E2F4 was required for the development of the telencephalon. Analysis of E2F4 deficient mouse embryos revealed that loss of E2F4 led to severe morphological defects in early ventral telencephalic development. Specifically, ganglionic eminences were absent and expression of the regional homeobox transcription factors was significantly reduced, suggesting that E2F4 is involved in the regulation of genes important for brain patterning. E2F4 deficiency also caused a reduction in neural stem cell number, indicating the requirement for E2F4 in regulation of neural stem cell self-renewal. To account for the aberrant telencephalic development, we showed that E2F4 deficiency lead to aberrant Shh signaling and impaired activity of forebrain-specific Shh enhancers. Activation of the Shh pathway with a Hh agonist restored cells expressing Nkx2.1 in explant cultures, as well as neural stem cell self-renewal. Finally, I identified a novel genetic interaction between E2F4 and Shh pathway in early telencephalic development. These studies demonstrated that E2F4 was required for ventral telencephalic development. Next, I determined whether E2F4 was required for eye patterning, which is closely linked to ventral telencephalic development and is regulated by Shh. I found that early eye morphogenesis and patterning was perturbed, such that optic stalk specific genes extended into the ventral optic cup with simultaneous reduction of the neural retinal markers. Also, Shh signaling was disrupted in the absence of E2F4. The Shh expression domain in the ventral hypothalamus was split and Shh activity was expanded into the ventral optic cup. These studies revealed a key role for E2F4 in early eye patterning. Overall, my findings reveal a novel requirement for E2F4 during early telencephalic and eye development, as well as in neural stem cells regulation.
Anesthesia in Cattle
Creators: name: Ames, N. Kent
name: Reibold, Thomas W.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: Due to the nature of cattle, most surgical procedures can be accomplishe1 with physical restraint and local anesthesia. This is an excellent method for most surgical procedures, but what about the procedures where more complete anesthesia is desired or required? How often is a surgical procedure not performed or performed inadequately because it would require the use of general anesthesia? First, let us look at the use of local and regional anesthesia. Local anesthetic agents prevent the conduction of nerve impulses along the nerves and thus, the patient perceives no pain. The concepts of general anesthesia in cattle are very similar to anesthesia in other animals, except for a few species variations. Prior to anesthetizing any animal, a few precautions are necessary. A routine physical exam should be performed to determine the state of health of the animal. Particular attention should be paid to the cardiopulmonary system. Basic clinical pathology tests should be performed to obtain baseline data for the animal. These tests would include a complete blood count, serum electrolytes, minerals, blood urea nitrogen, and serum glutamic oxaloacetic transaminase. Animals with metabolic disturbances are poorer anesthetic risks than healthy animals.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
Microstructural and Mechanistic Insights into the Tension-Compression Asymmetry of Rapidly Solidified Fe-Cr Alloys: A Phase Field and Strain Gradient Plasticity Study
Creators: name: Pai, Namit
name: Samajdar, Indradev
name: Patra, Anirban
Publisher: name: arXiv
Year: 2024
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Rapid solidification in Additively Manufactured (AM) metallic materials results in the development of significant microscale internal stresses, which are attributed to the printing induced dislocation substructures. The resulting backstress due to the Geometrically Necessary Dislocations (GNDs) is responsible for the observed Tension-Compression (TC) asymmetry. We propose a combined Phase Field (PF)-Strain Gradient $J_2$ Plasticity (SGP) framework to investigate the TC asymmetry in such microstructures. The proposed PF model is an extension of Kobayashi's dendritic growth framework, modified to account for the orientation-based anisotropy and multi-grain interaction effects. The SGP model has consideration for anisotropic temperature-dependent elasticity, dislocation strengthening, solid solution strengthening, along with GND-induced directional backstress. This model is employed to predict the solute segregation, dislocation substructure and backstress development during solidification and the post-solidification anisotropic mechanical properties in terms of the TC asymmetry of rapidly solidified Fe-Cr alloys. It is observed that higher thermal gradients (and hence, cooling rates) lead to higher magnitudes of solute segregation, GND density, and backstress. This also correlates with a corresponding increase in the predicted TC asymmetry. The results presented in this study point to the microstructural factors, such as dislocation substructure and solute segregation, and mechanistic factors, such as backstress, which may contribute to the development of TC asymmetry in rapidly solidified microstructures.
description: 30 pages, 12 figures
The Practitioner's Mastitis Laboratory
Creators: name: Anderson, Burleigh P.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: Samples should be plated as soon as possible after taking; however, they may be refrigerated for a period of time prior to plating. If samples are refrigerated for a 12- to 18-hour period, many times a preincubation of samples is advisable for an hour or two prior to plating. I personally find that this procedure is unnecessary many times. I have included a handwritten sheet indicating the method I follow in inoculating the culture plate. I will concentrate primarily on reading and interpreting the results of inoculating this particular plate. There are three types of media: the bright red media is blood agar and naturally permits the growth of almost all mastitis pathogens. The purple-red media is a special strep media, permitting the growth of only streptococci. The restrictive or inhibitory nature of this medium is due to the inclusion of thallium and crystal violet in media. The clear purple-blue-colored media is a media that permits only the growth of coliform organisms.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
BioExcel Webinar #28 - BioSimSpace – filling the gaps between molecular simulation codes
Creators: name: Woods, Christopher
Publisher: name: Zenodo
Year: 2018
Subjects: webinar

description: BioSimSpace (https://biosimspace.org) is a flagship software project from the CCP-BioSim (https://ccpbiosim.ac.uk) and HEC-BioSim (https://hecbiosim.ac.uk) biomolecular modelling communities. The project aims to make it easier for researchers to develop, share and re-use biomolecular simulation workflow nodes. The software problem in our community is that we have lots of different pieces of software that are all incompatible and are not interoperable. This forces the community to hand-write small scripts for converting between different file formats, or to generate different software input files. The resulting scripts are specific for the software and task performed, leading to the community generating lots of bespoke and brittle workflows. BioSimSpace solves this problem by providing an interoperability layer between the major molecular simulation packages. In effect, BioSimSpace provides the shims that fill in the gaps between codes. BioSimSpace python scripts can be run from the command line, used as workflow nodes in packages such as Knime, or run on the cloud as Jupyter notebooks. In this talk, we will show how BioSimSpace has been implemented, will talk about its capabilities and our future plans, and will demonstrate some BioSimSpace workflow nodes running on the cloud.
Ventilation for Calves and Youngstock
Creators: name: Hickert, William G.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: High humidities are especially detrimental to animal health. And it is the animals themselves that produce the moisture that may cause high humidities if adequate ventilation is not provided. Thus, in the winter, ventilation is required to remove the moisture generated by the animals. This may be mechanical ventilation (fans) or natural ventilation. In the summer, ventilation is required to remove both heat and moisture produced by the animals. Again, either mechanical or natural ventilation may be used. But the design and construction of the housing facility very much depends on whether ventilation is to be accomplished by mechanical or natural means.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
Armed with cameras: The Canadian Army Film Unit during the Second World War
Creators: name: Klotz, Sarah Beth
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: History, Canadian.

description: This thesis focuses on a previously undocumented part of Canadian military history: the Canadian Army Film Unit (CAFU). Like the official historians, war artists and photographers, the CAFU was to create an official record of Canada's Army in the Second World War. Although the National Film Board (NFB) was established in 1939, receiving complete control over the federal production of film in Canada, the CAFU was created in 1941 by the Department of National Defence outside of the mandate of the National Film Board Act. This caused a significant amount of conflict between the NFB and the Department of National Defence over which department would control the documentation of Canada's Army in the Second World War. Reconstructing the history of the Canadian Army Film Unit from 1941 to 1945, this thesis analyses a number of issues that the Film Unit encountered in the production of its motion pictures. This chronological study explores the nature of filming during combat, censorship, distribution, and the soldier-cameramen's ongoing struggle with the NFB for control over the documentation of the war on film. (Abstract shortened by UMI.)
Graph-theoretic analysis of gene expression networks
Creators: name: Haghighi, Maryam
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Mathematics.

description: We use graph theory to model a database of gene expression levels and provide a tool that can assist in designing biological experiments which could help to better understand the interactions between genes. The data was provided by StemBase (http://www.stembase.ca). We model a portion of this database as a graph, and study some parameters on it that may be biologically relevant. We include theoretical discussion of the parameters, and presentation of algorithms for their computation. The focus is on structural properties of the graph; thus, we investigate the graph's bipartiteness, connected components, distance between vertices, radius, diameter, center, cut-vertices and blocks, and its maximal and maximum cliques. We develop the terminology and results used for modeling the database, and implement some of the algorithms in MATLAB. We analyze the results of running the code on the database and discuss their relevance.
Cryosurgery
Creators: name: Farris, Harold E.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: Cryosurgery is the medical application of cold to destroy tissue. Since the first veterinary reports on cryosurgery in 1970 (1), cryosurgery has become a widely accepted modality for the treatment of skin cancer in animals (2,3,4). In food animal practice cryosurgery is widely used to treat bovine ocular squamous-cell carcinoma. A preliminary report on the cryosurgical treatment of interdigital fibromas, papillomatosis and fibromas of glans penis is presented. A treatment protocol that has resulted in a cure rate of more than 90% of bovine ocular squamouscell carcinomas and the cryosurgical instrumentation required in veterinary practice are discussed in detail.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
Recommendations for HLA-B*15:02 and HLA-A*31:01 genetic testing to reduce the risk of carbamazepine-induced hypersensitivity reactions
Creators: name: Amstutz, Ursula
name: Shear, Neil H.
name: Rieder, Michael J.
name: Hwang, Soomi
name: Fung, Vincent
name: Nakamura, Hidefumi
name: Connolly, Mary B.
name: Ito, Shinya
name: Carleton, Bruce C.
name: Canadian Pharmacogenomics Network For Drug Safety Clinical Recommendation Group
Publisher: name: Wiley
Year: 2017

description: Objective: To systematically review evidence on genetic risk factors for carbamazepine (CBZ)-induced hypersensitivity reactions (HSRs) and provide practice recommendations addressing the key questions: (1) Should genetic testing for HLA-B*15:02 and HLA-A*31:01 be performed in patients with an indication for CBZ therapy, in order to reduce the occurrence of CBZ-induced HSRs? (2) Are there subgroups of patients who may benefit more from genetic testing for HLAB* 15:02 or HLA-A*31:01 compared to others? (3) How should patients with an indication for CBZ therapy be managed based on their genetic test results? Methods: A systematic literature search was performed for HLA-B*15:02 and HLA-A*31:01 and their association with CBZ-induced HSRs. Evidence was critically appraised and clinical practice recommendations were developed based on expert group consensus. Results: Patients carrying HLA-B*15:02 are at strongly increased risk for CBZ-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in populations where HLA-B*15:02 is common, but not CBZ-induced hypersensitivity syndrome (HSS) or maculopapular exanthema (MPE). HLA-B*15:02-positive patients with CBZ-SJS/TEN have been reported from Asian countries only, including China, Thailand, Malaysia, and India. HLA-B*15:02 is very rare in Caucasians or Japanese where no HLA-B*15:02-positive patients with CBZ-SJS/TEN have been reported so far. HLA-A*31:01-positive patients are at increased risk for CBZ-induced HSS and MPE, and possibly SJS/TEN and acute generalized exanthematous pustulosis (AGEP). This association has been shown in Caucasian, Japanese, Korean, Chinese, and patients of mixed origin; however, HLA-A*31:01 is common in most ethnic groups. Not all patients carrying either risk variant develop a HSR, resulting in a relatively low positive predictive value of the genetic tests.
Rumen Acidosis and Related Complications
Creators: name: Vestweber, Jerry
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: Milk and meat production have become more dependent on the increased use of concentrates in the ration and whether these practices will continue with the known problems that exist and altered rumen fermentation that occurs, is dependent upon the continued advantage of use and solutions to modify the problems of high-concentrate rations. Rations that consist of primarily roughage provide enough energy to maintain the average annual milk production of approximately 10,000 lbs. per cow in the United States, but most cows have a genetic potential for more milk production and this can be obtained by increased use of grain. Kansas Dairy Herd Improvement records indicate the advantage of concentrate feedings for increased milk production. When dairy cows are fed high levels of concentrates, major changes in the rumen environment occur. Some of these changes are detrimental as described in the previous disease conditions. Numerous attempts have been made to use rumen buffers to counteract some of these negative effects (15,16,17,31). The effects of these buffers on volatile fatty acids, lactate production, and metabolism have been variable. If appropriate levels of supplementation can be determined, they may be useful in combating the negative effects of high-concentrate feeding.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
An integration test framework for service-oriented architecture
Creators: name: Seguin, Pierre
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Computer Science.

description: Increasingly organizations are leveraging service oriented architectures (SOA) as the core infrastructure on which their business applications and processes are organized. The testing and debugging of applications within a SOA presents special challenges. A defect observed at the level of user interaction with the application could be: (1) a fault (performance, security, scalability, etc.) in the application or process logic; (2) a fault in any of the services used by the application; (3) an unintended interaction in combining services. The key challenge to be faced is how to ensure that organizations can manage the complexity of their composite applications and service-oriented architecture in a manner that addresses the engineering requirements of testing while providing tools that are efficient, productive, and reasonable for testers to learn. In our thesis we address these issues by introducing a 'grey box' test agent architecture and a model-driven approach to express 'grey box' test campaigns.
Dairy Herd Health Program
Creators: name: Gibson, Charles D.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: The future of the veterinarian in the dairy industry will depend on the profession's ability to adapt to the changing needs of the industry and the computer will play a central role in the record-keeping system essential to this industry. We as veterinarians must be prepared to meet this challenge or we will be replaced by others outside the profession who will attempt to supply the demands of the industry. The success or failure of a dairy health program depends on several factors which include good records as well as other ingredients stated in this paper. A veterinarian must have the client's confidence, an educated client, an economic need and adequate veterinary manpower and skills in order to have a viable health program. When all of these ingredients are present, the result is a satisfied dairy client and a good economic return for the time investment by the veterinarian.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
Herd Health Presentation
Creators: name: MacKay, R. D.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 1978

description: Today, I would like to discuss the programmed herd health approach under the following headings : 1) Herd Health-Definitions, Goals and Objectives. 2) Herd Health-The Total Approach. 3) Personnel Involved in the Herd Health Program. 4) Specific Areas of the Herd Health Program-Methods, Goals, Results. 5) The Role of the Veterinarian.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 1978
Ureteral Stents and Foley Catheters-Associated Urinary Tract Infections : The Role of Coatings and Materials in Infection Prevention
Creators: name: Lo, Joey
name: Lange, Dirk (Microbiologist)
name: Chew, Ben H.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Urinary tract infections affect many patients, especially those who are admitted to hospital and receive a bladder catheter for drainage. Catheter associated urinary tract infections are some of the most common hospital infections and cost the health care system billions of dollars. Early removal is one of the mainstays of prevention as 100% of catheters become colonized. Patients with ureteral stents are also affected by infection and antibiotic therapy alone may not be the answer. We will review the current evidence on how to prevent infections of urinary biomaterials by using different coatings, new materials, and drug eluting technologies to decrease infection rates of ureteral stents and catheters.