title: ÐÐ±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ðµ ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ² Ð²ÑÐ¿Ð¸ÑÐºÐ¸ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ¾Ð² Ð¿Ð¾ÑÐ»Ðµ ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð½Ð¾Ð¹ ÑÐµÑÐ°Ð¿Ð¸Ð¸ ÐÑ-225
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Justification of discharge criteria for patients after radionuclide therapy with Ac-225
Creators: name: Ð¢ÐµÑÐµÐ½ÑÑÐµÐ²Ð°, ÐÐ½Ð°ÑÑÐ°ÑÐ¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: ÐÐ°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð½Ð°Ñ ÑÐµÑÐ°Ð¿Ð¸Ñ
Ð°ÐºÑÐ¸Ð½Ð¸Ð¹-225
ÑÐ°Ð´Ð¸Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ ÐºÑÐ¸ÑÐµÑÐ¸Ð¸ Ð²ÑÐ¿Ð¸ÑÐºÐ¸
ÑÐ°Ð´Ð¸Ð°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÑ
radionuclide therapy
actinium-225
radiological discharge criteria
radiation safety

description: Ð¦ÐµÐ»ÑÑ Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ Ð¾ÑÐµÐ½ÐºÐ° ÑÐ°Ð´Ð¸Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð²Ð¾Ð·Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ°, Ð¿ÑÐ¾ÑÐµÐ´ÑÐµÐ³Ð¾ ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð½ÑÑ ÑÐµÑÐ°Ð¿Ð¸Ñ ÐÑ-225, Ð½Ð° Ð¾ÐºÑÑÐ¶Ð°ÑÑÐ¸Ñ Ð»Ð¸Ñ Ð² ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐµ Ñ ÑÑÐµÑÐ¾Ð¼ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ°Ð´Ð¸Ð¾Ð°ÐºÑÐ¸Ð²Ð½ÑÑ Ð±Ð¸Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ñ Ð¾ÑÑÐ¾Ð´Ð¾Ð². ÐÐ°Ð´Ð°ÑÐ¸: 1. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÑÐµÐ½Ð°ÑÐ¸ÐµÐ² ÐºÐ¾Ð½ÑÐ°ÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ° Ð¿Ð¾ÑÐ»Ðµ Ð²ÑÐ¿Ð¸ÑÐºÐ¸ Ð¸Ð· ÐºÐ»Ð¸Ð½Ð¸ÐºÐ¸ Ñ Ð¾ÐºÑÑÐ¶Ð°ÑÑÐ¸Ð¼Ð¸ Ð»ÑÐ´ÑÐ¼Ð¸ Ð² ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐµ. 2. ÐÑÐµÐ½ÐºÐ° Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ°Ð´Ð¸Ð¾Ð°ÐºÑÐ¸Ð²Ð½ÑÑ Ð¾ÑÑÐ¾Ð´Ð¾Ð² Ð² Ð±Ð°ÐºÐ°Ñ Ð±Ð¸Ð¾ÑÑÐ°Ð»ÐµÑÐ¾Ð² ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ°. 3. ÐÐ¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÑÑÐµÐ½Ð°ÑÐ¸ÐµÐ² Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ñ Ð¸ Ð¾ÑÐµÐ½ÐºÐ° Ð´Ð¾Ð· Ð¿Ð°ÑÑÐ°Ð¶Ð¸ÑÐ¾Ð² Ð¸ ÑÐºÐ¸Ð¿Ð°Ð¶Ð° ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾Ð³Ð¾ ÑÑÐµÐ´ÑÑÐ²Ð° Ð¾Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ°, Ð¿ÑÐ¾ÑÐµÐ´ÑÐµÐ³Ð¾ ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð½ÑÑ ÑÐµÑÐ°Ð¿Ð¸Ñ ÐÑ-225. 4. ÐÐ¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÑÑÐµÐ½Ð°ÑÐ¸ÐµÐ² Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ñ Ð¸ Ð¾ÑÐµÐ½ÐºÐ° Ð´Ð¾Ð· Ð¿Ð°ÑÑÐ°Ð¶Ð¸ÑÐ¾Ð² Ð¸ ÑÐºÐ¸Ð¿Ð°Ð¶Ð° ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾Ð³Ð¾ ÑÑÐµÐ´ÑÑÐ²Ð° Ð¾Ñ Ð±Ð¸Ð¾ÑÑÐ°Ð»ÐµÑÐ¾Ð², ÑÐ¾Ð´ÐµÑÐ¶Ð°ÑÐ¸Ñ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð²ÑÐ¸ÐµÑÑ ÑÐ°Ð´Ð¸Ð¾Ð°ÐºÑÐ¸Ð²Ð½ÑÐµ Ð¾ÑÑÐ¾Ð´Ñ. Ð ÑÐ¾Ð´Ðµ Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð±ÑÐ» ÑÐ¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ°Ð½ÑÐ¾Ð¼ Ð² Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ðµ MCNP Ð¸ ÑÑÐ¸ ÑÑÐµÐ½Ð°ÑÐ¸Ñ ÐºÐ¾Ð½ÑÐ°ÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ°, Ð¿Ð¾ÑÐµÐ´ÑÐµÐ³Ð¾ ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð½ÑÑ ÑÐµÑÐ°Ð¿Ð¸Ñ ÐÑ-225, Ð¸ Ð¿Ð°ÑÑÐ°Ð¶Ð¸ÑÐ° Ð² ÑÐ°Ð·Ð½ÑÑ Ð²Ð¸Ð´Ð°Ñ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ°. ÐÐ¾Ð²ÐµÐ´ÐµÐ½Ð° Ð¾ÑÐµÐ½ÐºÐ° Ð´Ð¾Ð· Ð¾Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ° Ð¸ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð²ÑÐ¸ÑÑÑ ÑÐ°Ð´Ð¸Ð¾Ð°ÐºÑÐ¸Ð²Ð½ÑÑ Ð¾ÑÑÐ¾Ð´Ð¾Ð² Ð² ÑÐµÐ·ÐµÑÐ²ÑÐ°ÑÐ°Ñ ÑÑÐ¾ÑÐ½ÑÑ Ð²Ð¾Ð´ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾Ð³Ð¾ ÑÑÐµÐ´ÑÑÐ²Ð°. ÐÐ°Ð¸Ð±Ð¾Ð»ÐµÐµ ÐºÐ¾Ð½ÑÐµÑÐ²Ð°ÑÐ¸Ð²Ð½ÑÐ¼ Ð¾ÐºÐ°Ð·Ð°Ð»ÑÑ ÑÑÐµÐ½Ð°ÑÐ¸Ð¹ Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ñ Ð¿Ð°ÑÑÐ°Ð¶Ð¸ÑÐ° Ð² Ð²Ð°Ð³Ð¾Ð½Ðµ ÐºÑÐ¿Ðµ Ð¿Ð¾ÐµÐ·Ð´Ð°, ÐºÐ¾ÑÐ¾ÑÑÐ¹ Ð½Ð°ÑÐ¾Ð´Ð¸ÑÑÑ Ð² Ð¿ÑÑÐ¸ 48 ÑÐ°ÑÐ¾Ð². Ð¡ÑÐ¼Ð¼Ð°ÑÐ½Ð¾ Ð¾Ñ Ð±Ð°ÐºÐ° Ð¸ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ° Ð´Ð¾Ð·Ð° Ð½Ðµ Ð¿ÑÐµÐ²ÑÑÐ¸Ñ Ð·Ð½Ð°ÑÐµÐ½Ð¸Ñ 51,8 Ð¼ÐºÐÐ² Ð·Ð° 48 ÑÐ°ÑÐ¾Ð² Ð¿ÑÑÐ¸ Ð² Ð¿Ð¾ÐµÐ·Ð´Ðµ, ÑÑÐ¾ Ð½Ðµ Ð¿ÑÐµÐ²ÑÑÐ°ÐµÑ Ð³Ð¾Ð´Ð¾Ð²Ð¾Ð³Ð¾ Ð¿ÑÐµÐ´ÐµÐ»Ð° Ð´Ð¾Ð·Ñ Ñ Ð¾ÐºÑÑÐ¶Ð°ÑÑÐ¸Ñ Ð»Ð¸Ñ, ÐºÐ¾ÑÐ¾ÑÑÐ¹ ÑÐ¾ÑÑÐ°Ð²Ð»ÑÐµÑ 1 Ð¼ÐÐ² (1000 Ð¼ÐºÐÐ²) Ð² Ð³Ð¾Ð´ ÑÐ¾Ð³Ð»Ð°ÑÐ½Ð¾ ÐÐ Ð - 99/2009.
description: The aim of this study is to assess the radiation exposure of a patient who has undergone radionuclide therapy with Ac-225 to others in transportation settings, taking into account the generation of radioactive biological waste. Tasks: 1. Develop scenarios for patient contact with other people in transportation settings after discharge from the clinic. 2. Assess the generation of radioactive waste in the tanks of transport bio-toilets. 3. Model radiation exposure scenarios and assess the doses received by passengers and crew members from a patient who has undergone radionuclide therapy with Ac-225. 4. Model radiation exposure scenarios and assess the doses received by passengers and crew members from bio-toilets containing generated radioactive waste. In the course of this work, a mathematical phantom was modeled using the MCNP program, and three scenarios were developed for the contact between a patient who had undergone radionuclide therapy with Ac-225 and passengers in different types of transportation. An assessment was conducted of the doses from the patient and the radioactive waste generated in the wastewater tanks of the vehicle. The most conservative scenario was the exposure of a passenger in a train compartment car in transit for 48 hours. Overall, the dose from both the tank and the patient did not exceed 51.8 ÂµSv for 48 hours of travel on the train, which is below the annual dose limit for surrounding persons of 1 mSv (1000 ÂµSv) per year, according to NRB - 99/2009.