cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Filtering, clustering and dynamic layout for graph visualization
Creators: name: Huang, Xiaodi
Publisher: name: Swinburne
Year: 2024

description: Graph visualization plays an increasingly important role in software engineering and information systems. Examples include UML, E-R diagrams, database structures, visual programming, web visualization, network protocols, molecular structures, genome diagrams, and social structures. Many classical algorithms for graph visualization have already been developed over the past decades. However, these algorithms face difficulties in practice, such as the overlapping nodes, large graph layout, and dynamic graph layout. In order to solve these problems, this research aims to systematically address both algorithmic and approach issues related to a novel framework that describes the process of graph visualization applications. At the same time, all the proposed algorithms and approaches can be applied to other situations as well. First of all, a framework for graph visualization is described, along with a generic approach to the graphical representation of a relational information source. As the important parts of this framework, two main approaches, Filtering and Clustering, are then particularly investigated to deal with large graph layouts effectively. In order to filter 'noise' or less important nodes in a given graph, two new methods are proposed to compute importance scores of nodes called NodeRank, and then to control the appearances of nodes in a layout by ranking them. Two novel algorithms for clustering graphs, KNN and SKM, are developed to reduce visual complexity. Identifying seed nodes as initial members of clusters, both algorithms make use of either the k-nearest neighbour search or a novel node similarity matrix to seek groups of nodes with most affinities or similarities among them. Such groups of relatively highly connected nodes are then replaced with abstract nodes to form a coarse graph with reduced dimensions. An approach called MMD to the layout of clustered graphs is provided using a multiple-window - multiple-level display. As for the dynamic graph layout, a new approach to removing overlapping nodes called Force-Transfer algorithm is developed to greatly improve the classical Force- Scan algorithm. Demonstrating the performance of the proposed algorithms and approaches, the framework has been implemented in a prototype called PGD. A number of experiments as well as a case study have been carried out.
BindingDB Entry 12406: AAK1 INHIBITOR AND USE THEREOF
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: AP2-associated protein kinase 1, Xizang Haisco Pharmaceutical Co., Ltd., Affinity

description: Small molecule binding data for protein AP2-associated protein kinase 1, Uniprot Q2M2I8
Global forest resilience change from 2001 to 2022
Creators: name: Guo, Jing
name: Zhu, Zhiliang
name: Gong, Peng
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Forest resilience, the ecosystem’s capacity to withstand perturbations and retain primary functions and characteristics, is an essential indicator in evaluating the fate of an ecosystem under rapid climate change. Detailed information about forest resilience change, such as number of changes, direction (reduced vs increased), timing (start/end year), or duration of the change, is critical but is often not well demonstrated at the global scale. Here, we applied lag-one autocorrelation (AC1) as a forest resilience indicator on time series MODIS vegetation index images from 2001 to 2022 and employed LandTrendr spectral-temporal segmentation algorithms to track forest resilience change. Our results showed that the resilience of global forests changed nearly 3 times on average, and over 50% of global forests had an overall downward trend from the early 2000s up to recently. However, the current condition is changing for the better globally with approximately 53% of global forests currently showing an increased resilience during the recent change, and average patches of reduced resilience becoming smaller and more scattered. Over half of the forests in arid and temperate domains still show decreased resilience recently, which highlights the need for improved management practices.
BindingDB Entry 12405: PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Epidermal growth factor receptor [1-18,20-1210], Epidermal growth factor receptor [1-763,'FHEA',764-1210], and Receptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255], KOREA RESERARCH INSTITUTE OF CHEMICAL TECHNOLOGY; INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, Affinity

description: Small molecule binding data for protein Epidermal growth factor receptor [1-18,20-1210], Epidermal growth factor receptor [1-763,'FHEA',764-1210], and Receptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255], Uniprot P00533 and P04626
A novel pansharpening model based on two parallel network architectures
Creators: name: Li, Linze
name: Yang, Huan
name: Zhao, Pengcheng
name: Li, Jiansong
name: Zhao, Lingli
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer

description: Pansharpening is an important technology for obtaining high-resolution multispectral (HRMS) images by fusing low-resolution multispectral (LRMS) images and high-resolution panchromatic (PAN) images. Although many pansharpening models have emerged by taking advantage of deep learning (DL) technology, there remains a pressing need to further assess pansharpening accuracy and stability when LRMS images with complex land-cover types. What’s more, these models often overlook the exploitation of PAN images’ inherent high-frequency information. To address these issues, we propose a pansharpening model combining multi-level and multi-scale network architectures. The multi-level network architecture is used to build spatial-spectral dependence on LRMS-PAN pairs, and strengthen the network’s feature capture capability by keeping the multi-level texture details. The multi-scale architecture is subsequently used to extract the spatial structure and deep texture of the PAN images at different scales. Downsampled experiments and real experiments in four standard datasets show that the proposed model achieves a state-of-the-art performance.
BindingDB Entry 12404: PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Cyclic GMP-AMP synthase, Boehringer Ingelheim International, Affinity

description: Small molecule binding data for protein Cyclic GMP-AMP synthase, Uniprot Q8N884
BindingDB Entry 12403: TREATMENT OF CANCERS OR NEOPLASMS BY INHIBITING KIF15
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Kinesin-like protein KIF15/Targeting protein for Xklp2, University of Kansas, Affinity

description: Small molecule binding data for protein Kinesin-like protein KIF15/Targeting protein for Xklp2, Uniprot Q9NS87 and Q9ULW0
Managing social housing for indigenous populations
Creators: name: Burke, Terry
Publisher: name: Swinburne
Year: 2024

description: This paper provides a conceptual framework for understanding why and how indigenous cultures require culturally specific management practices in social housing, using Australian Aboriginals to illustrate the ideas. The framework is adapted from the field of intercultural management and is used to reveal how social housing provision and management for Australia’s indigenous population has largely failed to provide culturally appropriate solutions.
BindingDB Entry 12402: PHARMACEUTICAL COMBINATION AND APPLICATION THEREOF
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, GUANGZHOU JOYO PHARMATECH CO., LTD; SHANGHAI JIA TAN PHARMATECH CO., LTD., Affinity

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot O00329 and P48736
BindingDB Entry 12401: DEVELOPMENT AND OPTIMIZATION OF THIOCHROMENOTHIAZOLE-BASED MSUT2 INHIBITORS AS CANDIDATES FOR THE TREATMENT OF TAUOPATHY
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Zinc finger CCCH domain-containing protein 14, The United States Government As Represented By the Department of Veterans Affairs, Affinity

description: Small molecule binding data for protein Zinc finger CCCH domain-containing protein 14, Uniprot Q6PJT7
A holistic model for security of learning applications in smart cities
Creators: name: Caviglione, Luca
name: Coccoli, Mauro
Publisher: name: Journal of e-Learning and Knowledge Society
Year: 2020

description: Modern learning frameworks take advantage of the interconnection among individuals, multimedia artifacts, places, events, and physical objects. In this perspective, smart cities are primary providers of data, learning stimuli and realistic hands-on laboratories. Unfortunately, the development of smart-city-enabled learning frameworks leads to many privacy and security risks since they are built on top of IoT nodes, wireless sensors networks and cyber-physical systems. To efficiently address such issues, a suitable holistic approach is needed, especially to reveal the interdependence between different actors, e.g., cloud infrastructures, resource-constrained devices and big data sources. Therefore, this paper introduces a model to help the engineering of novel learning frameworks for smart cities by enlightening the problem space characterizing security.
description: Journal of e-Learning and Knowledge Society, Vol 16 No 1 (2020): Je-LKS - Special Issue on "Smart Learning in Smart Cities"
Improving elementary school’s critical thinking skills through three different learning media viewed from learning styles
Creators: name: Fajari, Laksmi Evasufi
name: Sarwanto
name: Chumdari
Publisher: name: Journal of e-Learning and Knowledge Society
Year: 2020

description: This research aims to analyze (1) the differences in critical thinking skills among students who were given three different PBL-assisted learning media; (2) the differences of critical thinking skills among visual and auditory students; and (3) the interaction between the three different learning media with learning styles on students’ critical thinking skills. This research is a quasi-experiment with a pretest-posttest non-equivalent control-group design. The population in this research is the fifth-grade students of the elementary school in Jebres Sub-district, Surakarta, Indonesia. The sampling technique used is cluster random sampling obtaining 96 students in three experimental classes at different schools. The data of critical thinking skills are gained from test scores. The data analysis technique used is descriptive quantitative statistics through ANCOVA test with the 3 x 2 factorial design. The results of the research revealed that there are different skills in critical thinking in different learning media. The highest skills in critical thinking are reached by students who were given differentiated problem-based learning (PBL) with multimedia in their learning. There are also differences in critical thinking skills between visual and auditory students.
description: Journal of e-Learning and Knowledge Society, Vol 16 No 1 (2020): Je-LKS - Special Issue on "Smart Learning in Smart Cities"
BindingDB Entry 12400: N-heterocyclic five-membered ring-containing capsid protein assembly inhibitor, pharmaceutical composition thereof, and use thereof
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD., Affinity

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P08684, P10635, P11712, P20813, and P33261
Technology to enable new paradigms of teaching/learning in mathematics: the digital interactive storytelling case
Creators: name: Albano, Giovannina
name: Coppola, Cristina
name: Dello Iacono, Umberto
name: Fiorentino, Giuseppe
name: Pierri, Anna
name: Polo, Maria
Publisher: name: Journal of e-Learning and Knowledge Society
Year: 2020

description: This paper concerns the design and implementation of a particular methodology for mathematics teaching/learning which exploits an interactive and immersive metaphor of storytelling. This research aims to promote processes such as inquiring, conjecturing, formalizing, proving in mathematics, and to investigate which is the best way to organize ICT tools to achieve that purpose. We also report the findings of an ongoing experimentation at the K12 school level.
description: Journal of e-Learning and Knowledge Society, Vol 16 No 1 (2020): Je-LKS - Special Issue on "Smart Learning in Smart Cities"
BindingDB Entry 12399: Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: 5-hydroxytryptamine receptor 2A, D(1A) dopamine receptor, and D(2) dopamine receptor, H. Lundbeck A/S, Affinity

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, D(1A) dopamine receptor, and D(2) dopamine receptor, Uniprot P14416, P21728, and P28223
BindingDB Entry 12398: 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives and the use thereof as medicament
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: G-protein coupled receptor 52, Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc., Affinity

description: Small molecule binding data for protein G-protein coupled receptor 52, Uniprot Q9Y2T5
РЕЗУЛЬТАТЫ БАРИАТРИЧЕСКОЙ ХИРУРГИИ ПРИ ОЖИРЕНИИ НА ФОНЕ САХАРНОГО ДИАБЕТА 2 ТИПА
Creators: name: Мадвалиев, Б.Б.
name: Абдуллажанов, Б.Р.
name: Ибрагимов, У.Я.
name: Сотиболдиев, А.А.
name: Ботиров, А.К.
name: Ботиров, Ж.А.
Publisher: name: Zenodo
Year: 2024

description: Ожирение – это хроническое заболевание, гетерогенное по этиологии и клиническим проявлениям, прогрессирующее при естественном течении, характеризующиеся избыточным отложением жировой массы в организме [11]. Морбидное ожирение - это патологическое состояние, при котором индекс массы тела превышает 40 кг/м2, т.е. масса тела повышена на 45-— 50% от нормальных ее значений [6]. По данным ВОЗ, четверть населения планеты страдает ожирением или имеет избыточную массу тела [10].
BindingDB Entry 12397: INHIBITORS OF 12/15-LIPOXYGENASE
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Polyunsaturated fatty acid lipoxygenase ALOX12/ALOX15, The General Hospital Corporation; The Regents of the University of California, Affinity

description: Small molecule binding data for protein Polyunsaturated fatty acid lipoxygenase ALOX12/ALOX15, Uniprot P16050 and P18054
BindingDB Entry 12396: Tricyclic Derivatives Useful As PARP7 Inhibitors
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Protein mono-ADP-ribosyltransferase TIPARP, JACOBIO PHARMACEUTICALS CO., LTD., Affinity

description: Small molecule binding data for protein Protein mono-ADP-ribosyltransferase TIPARP, Uniprot Q7Z3E1
BindingDB Entry 12395: 3CL PROTEASE SMALL-MOLECULE INHIBITOR FOR TREATING OR PREVENTING CORONAVIRUS INFECTION, AND USE THEREOF
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Replicase polyprotein 1a, THE GLOBAL HEALTH DRUG DISCOVERY INSTITUTE, Affinity

description: Small molecule binding data for protein Replicase polyprotein 1a, Uniprot P0DTC1
BindingDB Entry 12394: Compound Having Antitumor Activity And Use Thereof
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Protein arginine N-methyltransferase 5, lnnovStoneTherapeutics Limited, Affinity

description: Small molecule binding data for protein Protein arginine N-methyltransferase 5, Uniprot O14744
“A New Phase of Anti-Imperialist Cooperation”: The Making of Liberation Alliances in 1960s’ (Unliberated) Southern Africa
Creators: name: Moledo, Ana
Publisher: name: Leipziger Universitätsverlag
Year: 2019

description: Liberation struggles in Southern Africa were transnational and transregional since its inception in the early 1960s. Besides the involvement with Cold War powers and international actors, cooperation between liberation movements in the region became increasingly prominent towards the end of the decade. This article addresses the main cooperative arrangements and the process that led towards the consolidation of an alliance of Southern African liberation movements in 1969 in Khartoum. The forging of “revolutionary partnerships” was as much boosted by external supporters as pursued by the leadership of the liberation movements themselves, that sought to overcome hurdles of representation and legitimacy. Despite strategic aspirations for a stronger cooperation in the military and political realms, the Khartoum alliance was mainly oriented towards mobilizing the international public opinion in favour of this assemblage of “authentic” Southern African liberation movements.
description: Comparativ, Vol 29 No 4 (2019): The Momentous 1960s – Reflections on an African Decade
Brief DOAJ Application Checklist (2024 criteria)
Creators: name: University of Alberta Libraries
Publisher: name: Zenodo
Year: 2025

description: Summary checklist of the Directory of Open Access Journals (DOAJ) indexing application requirements as of 2024, created by the University of Alberta Libraries. A journal could use this document independently of a library publishing service to verify they have completed the necessary steps to be indexed in the DOAJ (2024). Journals should always check the DOAJ's website for the most up to date criteria. This document is provided for guidance only and does not guarantee that a journal will meet the criteria or be accepted for indexing.
Models, media and the perceptions of young women
Creators: name: Zubcevic-Basic, Nives
name: Reid, Mike
name: Mavondo, Felix
Publisher: name: Swinburne
Year: 2024

description: People often seek to satisfy the need for self-evaluation by comparing themselves with people who share similar characteristics as themselves. Often however media images form part of the foundation for comparison and idealised self benchmarking. This may have negative effects on more susceptible segments of the population. This exploratory study examines the beliefs of young women about characteristics and benefits of attractiveness and is a precursor to further research on the nature of attractiveness. The data, gained from 15-30 year old females, illustrates that the impact models in the media have on perceptions of self, others, and attractiveness, differs across clusters of the population on which media influence is greater, moderate or low.
The International Labour Organisation and its Bureau for Workers’ Activities (ACTRAV) in Africa on the Eve of the “Glorious” 1960s
Creators: name: Tijani, Hakeem Ibikunle
Publisher: name: Leipziger Universitätsverlag
Year: 2019

description: This article examines the International Labour Organisation’s (ILO) roles and impacts in labour relations and education in sub-Saharan Africa during the “glorious” 1960s. It historicise the genesis, challenges, and accomplishments in the area of labour union education – ACTRAV activities, its technical assistance programmes, Decent Work Projects, and its resolve to set international labour standards in sub-Saharan Africa. The setting of international labour standards is perhaps what separates the ILO from other international organisations as sub-Saharan colonies witnessed different levels of decolonisation during the post-World War II era. The article interrogates the place of sub-Saharan Africa in the mix of many annual sessions of the International Labour Congress (ILC) and its 200 conventions and a similar number of recommendations before the dawn of the 1960s. While the standards adopted in the early years were intended predominantly to protect workers in the physical performance of their work, as early as the 1930s the ILO had began to extend its standard-setting to a wider field of social policy, covering areas ranging from systems of social security to employment policy. The article examines the ILO’s Blueprint as it relates to its momentum in Africa and ACTRAV’s labour union education during the 1960s.
description: Comparativ, Vol 29 No 4 (2019): The Momentous 1960s – Reflections on an African Decade
BindingDB Entry 12393: ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform 2, BenevolentAI Cambridge Limited, Affinity

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform 2, Uniprot Q9Y233
MPEC 2024-V69 : 2024 VE1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 VE1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Zur Diskussion über die Bildung einer "Großchinesischen Wirtschaftsgemeinschaft"
Creators: name: Nieh, Yu-Hsi
Publisher: name: China aktuell
Year: 2019

description: Trotz der allgemein abflauenden Weltkonjunktur seit einem Jahr verzeichnen die drei chinesischen Wirtschaften - das chinesische Festland, Hongkong und Taiwan - einen anhaltenden Aufschwung. Im ersten Halbjahr 1992 betrug das Bruttosozialprodukt (BSP) der VR China ein reales Wachstum von 10% gegenüber dem Vorjahreszeitraum - weit über dem Jahresplan von 6% oder dem Ergebnis vom Vorjahr mit 7%. Die Industrieproduktion stieg beim selben Vergleich um 18,2% und die Anlageinvestitionen um 32,5% nach 14% bzw. 16,9% vor einem Jahr. Das Gesamtwertvolumen von Ex- und Import erreichte in den ersten sieben Monaten eine neue Höhe von 82,07 Mrd.US$, 19,3% mehr als im Vorjahreszeitraum.
description: China aktuell, China aktuell - August 1992
BindingDB Entry 12392: COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Dual specificity tyrosine-phosphorylation-regulated kinase 1A and Dual specificity tyrosine-phosphorylation-regulated kinase 1B, AVANTI BIOSCIENCES INC., Affinity

description: Small molecule binding data for protein Dual specificity tyrosine-phosphorylation-regulated kinase 1A and Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Uniprot Q13627 and Q9Y463
title: Changes in vascular elasticity due to the consumption of high salt: Sex differences
Creators: name: Mensah, Eric Abonah
Publisher: name: Memorial University of Newfoundland
publisherIdentifier: https://ror.org/04haebc03
publisherIdentifierScheme: ROR
Year: 2024

description: Arterial stiffness and alteration in vascular biomechanics play pivotal roles in circulatory dysfunction. Furthermore, the pharmacological responses of vasoactive agents on biomechanics are less defined in salt-induced hypertension in males versus females. Therefore, the studies undertaken for this thesis investigated the changes in the structure and biomechanics of small resistance arteries from salt-sensitive male and female Dahl rats fed regular and high salt diets for 6-7 weeks (n=6-8/group). Third-order mesenteric arteries were used, and the effects of pharmacological agents on biomechanics were assessed using pressure myography. Rats on a high salt diet (H) developed hypertension with elevated pulse wave velocity compared to rats on a regular diet (R). Morphometric assessment of the vessel wall indicated the possible development of hypertrophy with a significant increase in collagen and smooth muscle cell areas in males (H) compared (R) and the corresponding females. While no significant differences in composite Young's modulus (CYM) were found between groups, vasoconstriction (phenylephrine, 0.3 μM) resulted in significantly higher CYM in males (H) than (R) and the corresponding females on a high salt diet or regular diet. In contrast, vasodilation (sodium nitroprusside, 0.3 μM) significantly reduced CYM in the male groups (H) compared to the corresponding values in females (H). Inhibition of endothelial cell function using (L-NAME 0.3 μM, Ouabain 100 μM, and BaCl2 100 μM) or by denudation significantly increased CYM in male (R), female (R) and female (H) but not in male (H). Immunohistochemical assessment of biomechanical markers of arterial stiffness revealed significant sex differences, which may contribute to differential mechanisms of arterial stiffness in males versus females. Assessment of sex-specific contributions of Piezo 1 channels in vascular biomechanics indicated a differential expression of Piezo 1 mechanosensitive ion channels. In intact tissue, Piezo 1 antagonist, GsMTx-4 (2 μM), led to significant increases in CYM in male (R), female (R) and female (H) but not male (H). In contrast, in endothelial denuded vessels, GsMTx-4 produced a significant increase in CYM but only in females (R). These findings point to sex-specific changes in the ultrastructure and function of these arteries, which seem to alter the biomechanics and, thus, ultimately, the integrated function of macro- and micro-circulations.
title: Coupling Otolith Microstructure Analysis and Hydrographic Backtracking Suggests a Mechanism for the 2000s North Sea Herring Recruitment Failure
Creators: name: Ross, Stine D.
name: Payne, Mark R.
name: Clausen, Lotte Worsøe
name: Munk, Peter
name: Mosegaard, Henrik
name: Nash, Richard D.M.
Publisher: name: ASC 2012 - Theme session J
Year: 2024
Subjects: Fisheries and aquaculture
Ecosystem observation, processes and dynamics

description: No abstracts are to be cited without prior reference to the author.The North Sea autumn spawning herring (Clupea harengus L.) has, since the 2002 year class, shown an unprecedented sequence of ten years of sharply reduced recruitment, in spite of a high spawning biomass and low fishing mortality. Recent work has identified this reduction in recruitment level (or stock productivity) as taking place during the larval over-wintering phase: however, the underlying mechanism remains elusive. In this study we analysed archived larval samples captured both before and after the onset of the reduced survival to test the hypothesis of a reduction in the larval growth rate. Individual larval growth rates, averaged over the 30 days prior to capture, were estimated for two hundred larval otoliths from four different years using a model-based analysis of the ring widths. The otolith measurements were complemented with additional information derived from hydrographic backtracking models (e.g. average temperature experienced, time available for feeding and spawning origin) to reconstruct the recent history of the larvae. A mixed-modelling approach was then employed to analyse the combined data: after correcting for the effect of the other variables, a significant reduction in larval growth rate, associated with the onset of the reduced recruitment, was identified. These results suggest that the reduced recruitment is associated with a reduction in the growth rate of the larval survivors, most probably through changes in either the amount or quality of the available food. Furthermore, this study demonstrates how coupling two different techniques (otolith microstructure analysis and hydrographic modelling) can yield unique insights into fish ecology.
BindingDB Entry 12391: NOVEL CYCLOPROPYL COMPOUNDS
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Potassium voltage-gated channel subfamily KQT member 2, ICAGEN, LLC; HOFFMANN-LA ROCHE INC., Affinity

description: Small molecule binding data for protein Potassium voltage-gated channel subfamily KQT member 2, Uniprot O43526
Wo steht China heute? Die Rückkehr der Tradition und die Zukunft des Reformwerks
Creators: name: Weggel, Oskar
Publisher: name: China aktuell
Year: 2019

description: Im traditionellen China herrschte, wie nahezu im gesamten übrigen Asien, das vertikale Organisationsmuster vor. Wer in Vater/Sohn-, Eltern/Kinder- und Führer/Gefolgschafts-Beziehungen zu denken pflegt, ist auf Vertikalität programmiert, während andererseits die vorrangige Beschäftigung mit Berufsgruppen (z.B. "alle Architekten"), Ständen (z.B. "alle Adligen"), Klassen (z.B. "das Proletariat", "die Bourgeoisie"), Funktionsgruppen ("alle Wähler") oder aber Rechtsadressaten auf einen im Sinne der Soziologie horizontalen Denkansatz hinweist.
description: China aktuell, China aktuell - August 1992
BindingDB Entry 12390: COMPOUND SERVING AS NLRP3 INHIBITOR
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: NACHT, LRR and PYD domains-containing protein 3, Hangzhou Innogate Pharma Co., Ltd., Affinity

description: Small molecule binding data for protein NACHT, LRR and PYD domains-containing protein 3, Uniprot Q96P20
BindingDB Entry 12389: FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Dipeptidyl peptidase 4, Presequence protease, mitochondrial, and Prolyl endopeptidase FAP, 3 B PHARMACEUTICALS GMBH, Affinity

description: Small molecule binding data for protein Dipeptidyl peptidase 4, Presequence protease, mitochondrial, and Prolyl endopeptidase FAP, Uniprot P27487, P97321, and Q5JRX3
Piecing together the puzzle: an interview with Peter Duncan
Creators: name: McFarlane, Brian
Publisher: name: Swinburne
Year: 2024

description: Prolific in the 1990s with black comedy 'what-if?' scenario 'Children of the Revolution' (1996), dinner-party-with-a-twist 'A Little Bit of Soul' (1998) and biopic of classical pianist Percy Grainger 'Passion' (1999), filmmaker Peter Duncan returns to Australian cinemas with 'Unfinished Sky' (2008). He speaks to Brian McFarlane about his work - past, present and future.
title: Coupling Otolith Microstructure Analysis and Hydrographic Backtracking Suggests a Mechanism for the 2000s North Sea Herring Recruitment Failure
Creators: name: Ross, Stine D.
name: Payne, Mark R.
name: Clausen, Lotte Worsøe
name: Munk, Peter
name: Mosegaard, Henrik
name: Nash, Richard D.M.
Publisher: name: ASC 2012 - Theme session J
Year: 2024
Subjects: Fisheries and aquaculture
Ecosystem observation, processes and dynamics

description: No abstracts are to be cited without prior reference to the author.The North Sea autumn spawning herring (Clupea harengus L.) has, since the 2002 year class, shown an unprecedented sequence of ten years of sharply reduced recruitment, in spite of a high spawning biomass and low fishing mortality. Recent work has identified this reduction in recruitment level (or stock productivity) as taking place during the larval over-wintering phase: however, the underlying mechanism remains elusive. In this study we analysed archived larval samples captured both before and after the onset of the reduced survival to test the hypothesis of a reduction in the larval growth rate. Individual larval growth rates, averaged over the 30 days prior to capture, were estimated for two hundred larval otoliths from four different years using a model-based analysis of the ring widths. The otolith measurements were complemented with additional information derived from hydrographic backtracking models (e.g. average temperature experienced, time available for feeding and spawning origin) to reconstruct the recent history of the larvae. A mixed-modelling approach was then employed to analyse the combined data: after correcting for the effect of the other variables, a significant reduction in larval growth rate, associated with the onset of the reduced recruitment, was identified. These results suggest that the reduced recruitment is associated with a reduction in the growth rate of the larval survivors, most probably through changes in either the amount or quality of the available food. Furthermore, this study demonstrates how coupling two different techniques (otolith microstructure analysis and hydrographic modelling) can yield unique insights into fish ecology
title: 03_0263
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Cloud Solutions for Open Software
Creators: name: Caldoni, Giulia
name: Coppini, Sara
Publisher: name: Zenodo
Year: 2023
Subjects: subject: FAIR software management
subject: Computational reproducibility
subject: FAIR research software
subject: Cloud-based systems
subject: Software

description:  

 

This work at the Univeristy of Bologna (UNIBO) is intended as a systematic literature review and a benchmark on the main cloud-based services with environment and system specifications for code reproducibility, mostly cloud notebooks, up to March 2023.  We first screened the available tools for supported languages, costs, collaboration, set-up modes, version control allowance, PID (Persistent Identifier) attribution, licensing, accessibility, privacy, metadata, if Open Source, and long-term preservation strategy. We conducted this evaluation to identify a tool compliant with the FAIR principles (particularly those declined for Research Software from FAIR4RS) while facilitating code reproducibility. A tailored focus was on Code Ocean, a computational workbench used to associate code with scientific publications. The study highlighted that the landscape of tools facilitating computational reproducibility is varied, and it is still challenging to find a single solution presenting all the features making it both usable and adherent to the FAIR principles to ensure seamless sharing of code that is reproducible. 

 

Background information:

In the era of data-driven research, software has become an essential tool for data generation and analysis. However, it cannot just be considered instrumental: initiatives such as the Software Sustainability Institute advocate recognizing software as a research output and clearly stating how its management can benefit research, especially if shared and referenced in scientific publications.

The emphasis on improving research reproducibility, which led to the conceptualization of the FAIR principles for research data in 2016, is also becoming relevant for research software (e.g., FAIR4RS – FAIR  Principles for Research Software). 

Development strategies are already consolidated in the community, yet the discussion on methods, tools, and guidelines concerning the computational reproducibility of published results is still open. The main barriers to overcome are connected not only to software’s sharing and preservation strategies (lack of source code, also along with raw data and protocols) but also to the need to consider its specific features, e.g., executability, composite nature, and continuous evolution and versioning (by recording relevant information about versions, parameters, and runtime environments). 

Various tools, such as workflow management systems, digital protocols systems, packaging, and containerization platforms, can facilitate code sharing and reduce barriers to computational reproducibility. Some publishers endorse adopting some of these tools to improve peer reviewing of research code.
BindingDB Entry 12388: N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Sodium channel protein type 8 subunit alpha and Sodium channel protein type 9 subunit alpha, Eurofarma Laboratórios S.A.; Universidade Federal do Rio de Janeiro - UFRJ, Affinity

description: Small molecule binding data for protein Sodium channel protein type 8 subunit alpha and Sodium channel protein type 9 subunit alpha, Uniprot Q15858 and Q9UQD0
On Parallel Tracks at Different Speeds: Historiographies of Imperial Russia and the Globalized World around 1900
Creators: name: Aust, Martin
Publisher: name: Leipziger Universitätsverlag
Year: 2019

description: Elaborating on the history of nineteenth-century Russia, this article argues that world-regional histories and the global history approach benefit from each other. Global history has to be informed by source-based inquiries in spaces where the regional and the global meet. In the past three decades historians of nineteenth-century Russia and global historians have been affected by related imperatives: historians of Russia deconstructed a russocentric view of Russia’s past which veiled the diversity of a multiethnic empire while global historians reached out to deconstruct a eurocentric reading of world history. The article highlights case studies of Princess Olga Aleksandrovna Shcherbatova and Fedor Fedorovich Martens which shed light onto Russians‘ involvement in exploring and internationalizing the world in the late nineteenth and early twentieth century.
description: Comparativ, Vol 29 No 2 (2019): Global History and Area Histories
BindingDB Entry 12387: 1-H-PYRROLO[2,3-c]PYRIDINE COMPOUNDS
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Menin and Muscarinic acetylcholine receptor M2, Acerta Pharma B.V., Affinity

description: Small molecule binding data for protein Menin and Muscarinic acetylcholine receptor M2, Uniprot O00255 and P08172
BindingDB Entry 12386: SMALL MOLECULE INHIBITION OF DEUBIQUITINATING ENZYME JOSEPHIN DOMAIN CONTAINING 1 (JOSD1) AS A TARGETED THERAPY FOR LEUKEMIAS WITH MUTANT JANUS KINASE 2 (JAK2)
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Josephin-1 and Ubiquitin carboxyl-terminal hydrolase isozyme L1, DANA-FARBER CANCER INSTITUTE, INC., Affinity

description: Small molecule binding data for protein Josephin-1 and Ubiquitin carboxyl-terminal hydrolase isozyme L1, Uniprot P09936 and Q15040
Connections in Global History
Creators: name: Wenzlhuemer, Roland
Publisher: name: Leipziger Universitätsverlag
Year: 2019

description: The academic field of global history has recently started to enter into a phase of consolidation that necessitates us to rethink the scientific aims of the field, the questions it tackles as well as the instruments that it has at its disposal. In this regard, the article seeks to reconceptualize the notion of global connections that is so central to the field. It suggests to analytically focus on four aspects of global connections that have often been neglected: their role as mediators, their existence in the plural, their subtlety as well as their relation to other connections or disconnections.
description: Comparativ, Vol 29 No 2 (2019): Global History and Area Histories
Global History as Polycentric History
Creators: name: Scheuzger, Stefan
Publisher: name: Leipziger Universitätsverlag
Year: 2019

description: The article identifies an imbalance in the attention given to global history’s two fundamental objectives, the focus hitherto having fallen more on the study of cross-border connections than on the vaunted decentring of historiographical perspective. The example of the modern history of the prison serves to illustrate some basic problems faced by efforts to identify cross-border transfers and assess their historical significance for local, national or regional developments. The need for a decentring of historiographical perspectives is illustrated firstly by reference to the fact that, contrary to the established narrative, the globalization of the prison was a process characterized by a multiplicity of shifting centres. To help grasp such global processes it proposes the concept of a multiple “frame of references”. Secondly, the article emphasizes the importance to global historical research, alongside attention to transfers, of the comparative approach. Deploying the distinction between “hard” and “soft” versions of global history, it finally distinguishes between polycentric global history and global history still written from the standpoint of area history, only the former properly engaging with the globality of historical phenomena.
description: Comparativ, Vol 29 No 2 (2019): Global History and Area Histories
Empire, Enlightenment, and the Time Before: Global Contexts for Writing the History of Mexico
Creators: name: Marcovich, Gabriela Goldin
name: Sebastiani, Silvia
Publisher: name: Leipziger Universitätsverlag
Year: 2019

description: This article examines the different trajectories and works of two Mexican Creoles, separated by the Jesuits’ exile in 1767 in two different sides of the Atlantic. Francisco Javier Clavijero (1731–1787) wrote the monumental Storia antica del Messico (1780–1781) in the papal states, then a major center of antiquarian knowledge in Europe. José Antonio de Alzate y Ramírez (1737–1799) edited his Gazeta de literatura de México (1784–1795) in Mexico City and wrote notes on Clavijero’s history for a never published Spanish edition. This article shifts attention away from the “dispute of the New World” opposing European and American voices and concentrates instead on the very rich but still unstudied debate between Mexican Creoles. It suggests that the exile placed Clavijero and Alzate within different imperial configurations, and this had significant implications on their political agendas and epistemological approaches. By investigating the strategies that they employed for shaping their international credibility as local experts of Mexico’s pre-colonial history and architectural remains, this article also explores the fluctuating reception of Clavijero’s and Alzate’s works in a period characterized by significant imperial transformations.
description: Comparativ, Vol 29 No 3 (2019): Empires reconfigured
BindingDB Entry 12385: N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV 1.7 AND/OR NAV 1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME AND KITS
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Sodium channel protein type 8 subunit alpha and Sodium channel protein type 9 subunit alpha, EUROFARMA LABORATÓRIOS S.A.; Universidade Federal do Rio de Janeiro - UFRJ, Affinity

description: Small molecule binding data for protein Sodium channel protein type 8 subunit alpha and Sodium channel protein type 9 subunit alpha, Uniprot Q15858 and Q9UQD0
“Neocolonialism” Revisited: An Empirical Enquiry into the Term’s Theoretical Substance Today
Creators: name: Von Hirschhausen, Ulrike
name: Kreienbaum, Jonas
Publisher: name: Leipziger Universitätsverlag
Year: 2019

description: The term “neocolonialism” refers to the situation of former colonies remaining dependent on the metropoles and institutions of the West even after they achieved formal independence from the old European empires. In the 1960s and 1970s the term became a central category of analysis for anticolonial thought and even today, in the face of another wave of globalization, it serves as an explanatory factor. This essay examines the term’s analytical power by confronting it with two specific historical case studies. These are the British Empire’s economic intervention in Indian Bengal between 1870 and 1930 and the engagement of international financial institutions in central African Zambia in the name of structural adjustment during the late 1970s and 1980s. Notwithstanding certain continuities in unequal economic relations beyond the point of political decolonization, the essay argues that the concept of “neocolonialism” is not helpful as an analytical tool. It neglects local agency, overemphasizes the power of the imperial or neocolonial metropole and ignores the actual transformation of international economic relations. Instead, the article advocates the term “global capitalism”, which better grasps the ambivalent motives and consequences of economic interventions without disguising existing power differentials.
description: Comparativ, Vol 29 No 3 (2019): Empires reconfigured
BindingDB Entry 12384: Thiazole derivatives and pharmaceutically acceptable salts thereof
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2025
Subjects: Cyclin-dependent kinase 7, YUNGJIN PHARM. CO., LTD., Affinity

description: Small molecule binding data for protein Cyclin-dependent kinase 7, Uniprot P50613
The Early Modern “Silk-Road”. The Role of European, Chinese, and Russian Trade Reassessed
Creators: name: Ciriacono, Savatore
Publisher: name: Leipziger Universitätsverlag
Year: 2019

description: This paper investigates the historic and contemporary place of European and Asian trade in the context of the so-called “Silk Road”. The success and the competition of the present-day Chinese economy is seen as the cause of the declining role of Western economies in world markets but the reality is and was much more complex in the past. Was the Industrial revolution a fundamental turning point? In Central Asia in particular the institutional and economic rapports were much more nuanced than one might be led to believe by the notion of the “Silk Road” as a mere route of East-West transit. It is with this in mind that I consider the rapports between the maritime road and the silk road. I interpret the growing presence of Russia in the Central Asian markets from the sixteenth century onwards in connection with the Chinese advance in Western Asia. The English ambition and presence in Southern Asia (India) was also concerned with central Asian markets and was in direct competition with Russian expansion. These economic and institutional rapports went on to have a deep influence on 19th and 20th century geopolitics, in which the general concept of the Silk Road developed.
description: Comparativ, Vol 29 No 3 (2019): Empires reconfigured