cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MRX809924_Supplemental_Material - The Return of Citizenship? An Empirical Assessment of Legal Integration in Times of Radical Sociolegal Transformation
Creators: name: Moreh, Chris
name: McGhee, Derek
name: Vlachantoni, Athina
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: MRX809924_Supplemental_Material for The Return of Citizenship? An Empirical Assessment of Legal Integration in Times of Radical Sociolegal Transformation by Chris Moreh, Derek McGhee, and Athina Vlachantoni in International Migration Review
Memory control immediately improves unpleasant emotions associated with autobiographical memories of past immoral actions
Creators: name: Satish, Akul
name: Hellerstedt, Robin
name: Anderson, Michael C.
name: Bergström, Zara M.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: The ability to stop unwanted memories from coming to mind is theorised to be essential for maintaining good mental health. People can employ intentional strategies to prevent conscious intrusions of negative memories, and repeated attempts to stop retrieval both reduces the frequency of intrusions and improves subsequent emotions elicited by those memories. However, it is still unknown whether memory control can improve negative emotions immediately, at the time control is attempted. It is also not clear which strategy is most beneficial for emotion regulation; clearing the mind of any thoughts of negative memories via direct suppression, or substituting memory recall with alternative thoughts. Here, we provide novel evidence that memory control immediately regulates negative emotions associated with autobiographical memories of morally wrong actions. Repeated control significantly improved negative emotions over time, regardless of the strategy used to implement control. Thought substitution involving either positive diversionary thinking or counterfactual thinking both induced positive feelings, whereas direct suppression neutralised emotions, regardless of whether memories were positive or negative. These empirical findings have implications for clinical practice as they indicate that memory control strategies could be effective emotion regulation methods for real-world intrusive memories.
MSJ814117_supplementary_figure_5 – Supplemental material for Slowly expanding/evolving lesions as a magnetic resonance imaging marker of chronic active multiple sclerosis lesions
Creators: name: Elliott, Colm
name: Wolinsky, Jerry S
name: L Hauser, Stephen
name: Kappos, Ludwig
name: Barkhof, Frederik
name: Bernasconi, Corrado
name: Wei, Wei
name: Belachew, Shibeshih
name: Arnold, Douglas L
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care

description: Supplemental material, MSJ814117_supplementary_figure_5 for Slowly expanding/evolving lesions as a magnetic resonance imaging marker of chronic active multiple sclerosis lesions by Colm Elliott, Jerry S Wolinsky, Stephen L Hauser, Ludwig Kappos, Frederik Barkhof, Corrado Bernasconi, Wei Wei, Shibeshih Belachew and Douglas L Arnold in Multiple Sclerosis Journal
Appendix E - Supplemental material for Fetal Anthropometric Features: A Postmortem Study of Fetuses After the Termination of Pregnancy for Psychosocial Reasons Between 12 and 20 Gestational Weeks
Creators: name: Anne-Claude Muller Brochut
name: Taffe, Patrick
name: Piaget-Rossel, Romain
name: Leval, Laurence De
name: Anne-Laure Rougemont
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111403 Paediatrics
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, Appendix E for Fetal Anthropometric Features: A Postmortem Study of Fetuses After the Termination of Pregnancy for Psychosocial Reasons Between 12 and 20 Gestational Weeks by Anne-Claude Muller Brochut, Patrick Taffe, Romain Piaget-Rossel, Laurence de Leval and Anne-Laure Rougemont in Pediatric and Developmental Pathology
Threat priming diminishes the gaze cueing effect
Creators: name: Zhai, Manman
name: Hietanen, Jari K.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Gaze cueing effect (GCE) refers to attention orienting towards the gazed-at location, characterised by faster responses to gazed-at than non-gazed-at stimuli. A previous study investigated the effects of affective priming on GCE and reported that threatening primes enhanced GCE. However, it remains unknown whether the threat or heightened arousal potentiated GCE. We investigated how highly arousing threatening and positive primes, compared to low arousing neutral primes modulate GCE. After a brief exposure to an affective prime (pictures of threat or erotica) or a neutral prime, participants detected an asterisk validly or invalidly cued by the gaze direction of a neutral face. The results showed that the threatening primes diminished the magnitude of GCE. The highly arousing positive primes did not have an effect on GCE. Further analyses showed that, as compared to neutral priming, the reaction times after threatening primes were shortened on invalid trials. This finding was interpreted to suggest that the threatening primes enhanced goal-directed target detection and attenuated attention orienting by irrelevant gaze cues via improving executive control. In sum, the present findings indicate that threat priming modulates GCE, not because of heightened arousal but because of the threat.
Supplemental_Figure_1 - Passive Leg Raise: Feasibility and Safety of the Maneuver in Patients With Undifferentiated Shock
Creators: name: Toppen, William
name: Montoya, Elizabeth Aquije
name: Ong, Stephanie
name: Markovic, Daniela
name: Yuhan Kao
name: Xueqing Xu
name: Chiem, Alan
name: Cannesson, Maxime
name: Berlin, David
name: Barjaktarevic, Igor
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 110203 Respiratory Diseases

description: Supplemental_Figure_1 for Passive Leg Raise: Feasibility and Safety of the Maneuver in Patients With Undifferentiated Shock by William Toppen, Elizabeth Aquije Montoya, Stephanie Ong, Daniela Markovic, Yuhan Kao, Xueqing Xu, Alan Chiem, Maxime Cannesson, David Berlin, and Igor Barjaktarevic in Journal of Intensive Care Medicine
Sustaining attention in affective contexts during adolescence: age-related differences and association with elevated symptoms of depression and anxiety
Creators: name: Dunning, D. L.
name: Parker, J.
name: Griffiths, K.
name: Bennett, M.
name: Archer-Boyd, A.
name: Bevan, A.
name: Ahmed, S.
name: Griffin, C.
name: Foulkes, L.
name: Leung, J.
name: Sakhardande, A.
name: Manly, T.
name: Kuyken, W.
name: Williams, J.M.G.
name: Blakemore, S.-J.
name: Dalgleish, T.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Sustained attention, a key cognitive skill that improves during childhood and adolescence, tends to be worse in some emotional and behavioural disorders. Sustained attention is typically studied in non-affective task contexts; here, we used a novel task to index performance in affective versus neutral contexts across adolescence (N = 465; ages 11–18). We asked whether: (i) performance would be worse in negative versus neutral task contexts; (ii) performance would improve with age; (iii) affective interference would be greater in younger adolescents; (iv) adolescents at risk for depression and higher in anxiety would show overall worse performance; and (v) would show differential performance in negative contexts. Results indicated that participants performed more poorly in negative contexts and showed age-related performance improvements. Those at risk of depression performed more poorly than those at lower risk. However, there was no difference between groups as a result of affective context. For anxiety there was no difference in performance as a function of severity. However, those with higher anxiety showed less variance in their reaction times to negative stimuli than those with lower anxiety. One interpretation is that moderate levels of emotional arousal associated with anxiety make individuals less susceptible to the distracting effects of negative stimuli.
Chester__Online_Appendix – Supplemental material for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure
Creators: name: Chester, David S.
name: C. Nathan DeWall
name: Enjaian, Brian
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Chester__Online_Appendix for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure by David S. Chester, C. Nathan DeWall and Brian Enjaian in Personality and Social Psychology Bulletin
SadismAgg_SupplementalTable10 – Supplemental material for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure
Creators: name: Chester, David S.
name: C. Nathan DeWall
name: Enjaian, Brian
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, SadismAgg_SupplementalTable10 for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure by David S. Chester, C. Nathan DeWall and Brian Enjaian in Personality and Social Psychology Bulletin
SadismAgg_SupplementalTable12 – Supplemental material for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure
Creators: name: Chester, David S.
name: C. Nathan DeWall
name: Enjaian, Brian
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, SadismAgg_SupplementalTable12 for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure by David S. Chester, C. Nathan DeWall and Brian Enjaian in Personality and Social Psychology Bulletin
SadismAgg_SupplementalTable13 – Supplemental material for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure
Creators: name: Chester, David S.
name: C. Nathan DeWall
name: Enjaian, Brian
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, SadismAgg_SupplementalTable13 for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure by David S. Chester, C. Nathan DeWall and Brian Enjaian in Personality and Social Psychology Bulletin
Interpersonal helping in the workplace: social expectation predicts anticipated guilt and intention to help a coworker
Creators: name: Gherghel, Claudia
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Statistics
subject: FOS: Mathematics
subject: Science Policy
subject: Mental Health

description: Promoting interpersonal helping among coworkers is an important aim for any organisation that cares about employee well-being. Drawing on guilt aversion hypothesis, this research focuses on the power of social expectations in promoting prosocial behaviour among employees and investigates the role of anticipated guilt for failing to meet coworkers’ expectations. In two preregistered studies, the effect of beneficiary expectation on benefactors’ anticipated guilt and intention to help was investigated. In Study 1, Japanese participants (n = 284) recalled a situation when they helped a coworker spontaneously, and evaluated perceived beneficiary expectation to receive help, as well as anticipated guilt for not helping. Beneficiary expectation positively predicted anticipated guilt, and the effect was stronger when the beneficiary was a same-status colleague, and when interpersonal helping frequency in the organisation was low. Study 2 (n = 499) employed vignettes and manipulated beneficiary expectation. A mediational model revealed that beneficiary expectation leads to more anticipated guilt for not helping, which, in turn, increases employees’ intention to help. Together, these studies show that employees are sensitive to their coworkers’ expectations, and guilt-averse; therefore, interpersonal helping among employees may be promoted by establishing legitimate expectations of prosociality in the workplace.
SadismAgg_SupplementalTable14 – Supplemental material for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure
Creators: name: Chester, David S.
name: C. Nathan DeWall
name: Enjaian, Brian
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, SadismAgg_SupplementalTable14 for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure by David S. Chester, C. Nathan DeWall and Brian Enjaian in Personality and Social Psychology Bulletin
Revue Verlaine. 2016, n° 14
Creators: name: (:Unap)
Publisher: name: Classiques Garnier
Year: 2016
Subjects: subject: Paul Verlaine
subject: Littérature française du XIXe siècle
subject: Poésie
subject: Langage
subject: Approche critique

description: Contributeurs : Arnaud Bernadet, Éric Bordas, Alain Chevrier, Solenn Dupas, Aurélie Foglia-Loiseleur, Yann Frémy, Sandra Glatigny, Christian Hervé, Cyril Lhermelier, Steve Murphy, Daniel Ridge, Myriam Robic, Daniel Sangsue, Myriam Watthee-Delmotte et Seth Whidden.
SadismAgg_SupplementalTable5 – Supplemental material for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure
Creators: name: Chester, David S.
name: C. Nathan DeWall
name: Enjaian, Brian
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, SadismAgg_SupplementalTable5 for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure by David S. Chester, C. Nathan DeWall and Brian Enjaian in Personality and Social Psychology Bulletin
SadismAgg_SupplementalTable6 – Supplemental material for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure
Creators: name: Chester, David S.
name: C. Nathan DeWall
name: Enjaian, Brian
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, SadismAgg_SupplementalTable6 for Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure by David S. Chester, C. Nathan DeWall and Brian Enjaian in Personality and Social Psychology Bulletin
Overestimating the intensity of negative feelings in autobiographical memory: evidence from the 9/11 attack and COVID-19 pandemic
Creators: name: Castillo, Juan
name: Fan, Haoxue
name: Karaman, Olivia T.
name: Shu, Jocelyn
name: Stussi, Yoann
name: Kredlow, M. Alexandra
name: Vranos, Sophia
name: Oyarzún, Javiera P.
name: Dorfman, Hayley M.
name: Sambrano, Deshawn Chatman
name: Meksin, Robert
name: Hirst, William
name: Phelps, Elizabeth A.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Mental Health

description: When recalling autobiographical events, people not only retrieve event details but also the feelings they experienced. The current study examined whether people are able to consistently recall the intensity of past feelings associated with two consequential and negatively valenced events, i.e. the 9/11 attack (N = 769) and the COVID-19 pandemic (N = 726). By comparing experienced and recalled intensities of negative feelings, we discovered that people systematically recall a higher intensity of negative feelings than initially reported – overestimating the intensity of past negative emotional experiences. The COVID-19 dataset also revealed that individuals who experienced greater improvement in emotional well-being displayed smaller biases in recalling their feelings. Across both datasets, the intensity of remembered feelings was correlated with initial feelings and current feelings, but the impact of the current feelings was stronger in the COVID-19 dataset than in the 9/11 dataset. Our results demonstrate that when recalling negative autobiographical events, people tend to overestimate the intensity of prior negative emotional experiences with their degree of bias influenced by current feelings and well-being.
Formation of Peroxynitrite, [O−N−O−O]−, via a Cascade of Reactions between Ozonide and Ammonia
Creators: name: Schmid, Jonas R.
name: Rennefeld, Oliver R. H.
name: Wiesner, Anja
name: Jansen, Martin
name: Riedel, Sebastian
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Ozonide
subject: Peroxynitrite
subject: Fluorine specific interactions
subject: X-ray diffraction
subject: Radicals
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: We report on an unexpected reaction between ammonia and potassium ozonide dissolved in liq. NH3 resulting in the formation of peroxynitrite, [ONOO]−, which exclusively happens in the presence of a specific partially fluorinated aniline-based ammonium cation. High-resolution structural data of the peroxynitrite anion in cis-conformation have been obtained. We further studied this molecule anion by single crystal Raman spectroscopy. The cis and trans isomers of peroxynitrite were analysed computationally with respect to their relative energies, the cis-trans transition barrier and their decomposition pathways to the nitrate anion. By experimentally examining cations decorated with fluorine ligands to different degrees, we demonstrate that fluorine specific interactions play a crucial role in the unexpected formation of peroxynitrite and as a conspicuously structure directing factor for the underlying crystalline solid phases, exhibiting distinct micro-separations of fluorine and hydrogen enriched regions.
Cassini’s CDA observes a variety of dust populations just outside Saturn’s main rings
Creators: name: Linti, Simon
name: Khawaja, Nozair
name: Hillier, Jon K.
name: Nölle, Lenz
name: Fischer, Christian
name: Hsu, Hsiang-Wen
name: Srama, Ralf
name: Postberg, Frank
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: methods: data analysis
subject: planets and satellites: individual: Saturn
subject: planets and satellites: rings
subject: 500 Naturwissenschaften und Mathematik::520 Astronomie::520 Astronomie und zugeordnete Wissenschaften

description: Before the end of its mission, the Cassini spacecraft orbited Saturn in a series of highly inclined elliptical ‘Ring-Grazing’ orbits (RGO). During the RGO, the spacecraft passed repeatedly through the ring plane outside the F ring, near the orbits of Janus and Epimetheus, at an average relative speed of ∼20 km s–1. For the first time, Cassini’s Cosmic Dust Analyser (CDA) directly sampled dust particles from this region. Here, we analyse the compositions of dust grains sampled within ±15 min relative to nine ring plane crossings of the RGO. The compositions of most analysed RGO grains are similar to those of E ring ice grains, implying that the E ring extends to within at least 2.45 Saturn radii (RS) of Saturn. The compositional distribution of these grains point at a similar average period (decades) since ejection from Enceladus as of particles in the outer E ring (beyond 8 RS). Higher fractions of larger grains are found near the orbits of Janus and Epimetheus, which probably represent ejecta from these moons. Most of these grains have compositions similar to the background E ring grains, indicating that E ring material is coating the surfaces of Janus and Epimetheus. We also report the detection of several types of mineral grains on prograde orbits, one of which, a water ice/silicate mixture, has never been observed by CDA elsewhere. These mineral grains appear to have a different origin from the E ring, and may arise from nearby moons, the F ring, or main rings.
Ram_Supplemental_Material – Supplemental material for Prenatal Risk for ASD: Fetal Cortisol Exposure Predicts Child Autism-Spectrum-Disorder Symptoms
Creators: name: Ram, Sheena
name: Howland, Mariann A.
name: Sandman, Curt A.
name: Elysia Poggi Davis
name: Glynn, Laura M.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Ram_Supplemental_Material for Prenatal Risk for ASD: Fetal Cortisol Exposure Predicts Child Autism-Spectrum-Disorder Symptoms by Sheena Ram, Mariann A. Howland, Curt A. Sandman, Elysia Poggi Davis and Laura M. Glynn in Clinical Psychological Science
Rasmussen_Supplemental_Table – Supplemental material for When Did Posttraumatic Stress Disorder Get So Many Factors? Confirmatory Factor Models Since DSM–5
Creators: name: Rasmussen, Andrew
name: Verkuilen, Jay
name: Nuwan Jayawickreme
name: Zebing Wu
name: Sydne T. McCluskey
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Rasmussen_Supplemental_Table for When Did Posttraumatic Stress Disorder Get So Many Factors? Confirmatory Factor Models Since DSM–5 by Andrew Rasmussen, Jay Verkuilen, Nuwan Jayawickreme, Zebing Wu and Sydne T. McCluskey in Clinical Psychological Science
Optimal control and global stability of the SEIQRS epidemic model
Creators: name: Azoua, Mohammed
name: Azouani, Abderrahim
name: Hafidi, Imad
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: epidemiological models
subject: optimal control
subject: global stability
subject: Covid-19
subject: numerical simulation
subject: 500 Naturwissenschaften und Mathematik::510 Mathematik::510 Mathematik

description: Medical treatment, vaccination, and quarantine are the most efficacious controls in preventing the spread of contagious epidemics such as COVID-19. In this paper, we demonstrate the global stability of the endemic and disease-free equilibrium by using the Lyapunov function. Moreover, we apply the three measures to minimize the density of infected people and also reduce the cost of controls. Furthermore, we use the Pontryagin Minimum Principle in order to characterize the optimal controls. Finally, we execute some numerical simulations to approve and verify our theoretical results using the fourth order Runge-Kutta approximation through Matlab.
Supplemental material for Retinal vascular changes and right ventricular structure and function: the MESA-Right Ventricle and MESA-Eye studies
Creators: name: Chyou, Anthony C.
name: Klein, Barbara E.K.
name: Klein, Ronald
name: R. Graham Barr
name: Cotch, Mary Frances
name: Praestgaard, Amy
name: Wong, Tien Y.
name: Joao Lima
name: Bluemke, David A.
name: Kawut, Steven
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Cardiology
subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: Supplemental Material for Retinal vascular changes and right ventricular structure and function: the MESA-Right Ventricle and MESA-Eye studies by Anthony C. Chyou, Barbara E.K. Klein, Ronald Klein, R. Graham Barr, Mary Frances Cotch, Amy Praestgaard, Tien Y. Wong, Joao Lima, David A. Bluemke and Steven Kawut in Pulmonary Circulation
Mental Health, Happiness, and Moral Goodness
Creators: name: Rose, Hope
name: King, Laura A.
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Personality and Social Contexts
subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: We know that happy people are viewed as higher in moral goodness compared to the unhappy (King & Napa, 1998). Providing an explanatory cue to the source of a person’s unhappiness might mitigate the effect of unhappiness on moral judgments. The present study will examine whether mental health concerns, specifically depression, serve as such a cue. In addition, we will probe the potential effect of happiness (vs. unhappiness) on judgments of the likelihood that a target will engage in moral (and immoral) behavior, testing predictions rooted in the presumption that happiness signals good behavior and just world beliefs.
A Fluorinated Sialic Acid Vaccine Lead Against Meningitis B and C
Creators: name: Jordan, Christina
name: Siebold, Kathrin
name: Priegue, Patricia
name: Seeberger, Peter H.
name: Gilmour, Ryan
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Biopolymers
subject: Carbohydrates
subject: Immunology
subject: FOS: Clinical medicine
subject: Peptides and proteins
subject: Vaccination
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: Inspired by the specificity of α-(2,9)-sialyl epitopes in bacterial capsular polysaccharides (CPS), a doubly fluorinated disaccharide has been validated as a vaccine lead against Neisseria meningitidis serogroups C and/or B. Emulating the importance of fluorine in drug discovery, this molecular editing approach serves a multitude of purposes, which range from controlling α-selective chemical sialylation to mitigating competing elimination. Conjugation of the disialoside with two carrier proteins (CRM197 and PorA) enabled a semisynthetic vaccine to be generated; this was then investigated in six groups of six mice. The individual levels of antibodies formed were compared and classified as highly glycan-specific and protective. All glycoconjugates induced a stable and long-term IgG response and binding to the native CPS epitope was achieved. The generated antibodies were protective against MenC and/or MenB; this was validated in vitro by SBA and OPKA assays. By merging the fluorinated glycan epitope of MenC with an outer cell membrane protein of MenB, a bivalent vaccine against both serogroups was created. It is envisaged that validation of this synthetic, fluorinated disialoside bioisostere as a potent antigen will open new therapeutic avenues.
Parthanatos and apoptosis: unraveling their roles in cancer cell death and therapy resistance
Creators: name: Gupta, Gaurav
name: Afzal, Muhammad
name: Moglad, Ehssan
name: Goyal, Ahsas
name: Almalki, Waleed Hassan
name: Goyal, Kavita
name: Rana, Mohit
name: Ali, Haider
name: Rekha, Arcot
name: Kazmi, Imran
name: Alzarea, Sami I.
name: Singh, Sachin Kumar
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2025
Subjects: parthanatos
apoptosis
cancer
cell death mechanisms
PARP1
caspases
therapy resistance

description: Cell death is a fundamental process that needs to be maintained to balance cellular functions and prevent disease. There are several cell death pathways; however, apoptosis and parthanatos are the most prominent and have important roles in cancer biology. As an extremely well-regulated process, apoptosis removes damaged or abnormal cells via caspase activation and mitochondrial involvement. Unlike in the healthy cells, the loss of ability to induce apoptosis in cancer permits tumor cells to survive and multiply out of control and contribute to tumor progression and therapy resistance. On the contrary, parthanatos is a caspase-independent metabolic collapse driven by poly (ADP-ribose) polymerase 1 (PARP1) overactivation, translocation of apoptosis-inducing factor (AIF), and complete DNA damage. Several cancer models are involved with parthanatos. Deoxypodophyllotoxin (DPT) induces parthanatos in glioma cells by excessive ROS generation, PARP1 upregulation, and AIF nuclear translocation. Like in acute myeloid leukemia (AML), the cannabinoid derivative WIN-55 triggers parthanatos, and the effects can be reversed by PARP inhibitors such as olaparib. Developing cancer treatment strategies involving advanced cancer treatment strategies relies on the interplay between apoptosis and parthanatos. However, such apoptosis-based cancer therapies tend to develop resistance, so there is an urgent need to look into alternative pathways like parthanatos, which may not always trigger apoptosis. In overcoming apoptosis resistance, there is evidence that combining apoptosis-inducing agents, such as BH3 mimetics, with PARP inhibitors synergistically enhances cell death. Oxidative stress modulators have been found to promote the execution of parthanatic and apoptotic pathways and allow treatment. In this review, apoptosis and parthanatos are thoroughly compared at the molecular level, and their roles in cancer pathogenesis as related to cancer therapeutic potential are discussed. We incorporate recent findings to demonstrate that not only can parthanatos be used to manage therapy resistance and enhance cancer treatment via the combination of parthanatos and apoptosis but also that immunity and bone deposition can feasibly be employed against long-circulating cancer stem cells to treat diverse forms of metastatic cancers.
description: EXCLI Journal; 24:Doc351; ISSN 1611-2156
Degradation of hexosylceramides is required for timely corpse clearance via formation of cargo-containing phagolysosomal vesicles
Creators: name: Holzapfel, Rebecca
name: Prell, Agata
name: Schumacher, Fabian
name: Perschin, Veronika
name: Angeli, Jose Pedro Friedmann
name: Kleuser, Burkhard
name: Stigloher, Christian
name: Fazeli, Gholamreza
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Phagolysosome resolution
subject: Cell corpse clearance
subject: Lysosome
subject: Sphingolipidome
subject: Hexosylceramides
subject: Glucosyl ceramidases
subject: Polar body
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Efficient degradation of phagocytic cargo in lysosomes is crucial to maintain cellular homeostasis and defending cells against pathogens. However, the mechanisms underlying the degradation and recycling of macromolecular cargo within the phagolysosome remain incompletely understood. We previously reported that the phagolysosome containing the corpse of the polar body in C. elegans tubulates into small vesicles to facilitate corpse clearance, a process that requires cargo protein degradation and amino acid export. Here we show that degradation of hexosylceramides by the prosaposin ortholog SPP-10 and glucosylceramidases is required for timely corpse clearance. We observed accumulation of membranous structures inside endolysosomes of spp-10-deficient worms, which are likely caused by increased hexosylceramide species. spp-10 deficiency also caused alteration of additional sphingolipid subclasses, like dihydroceramides, 2-OH-ceramides, and dihydrosphingomyelins. While corpse engulfment, initial breakdown of corpse membrane inside the phagolysosome and lumen acidification proceeded normally in spp-10-deficient worms, formation of the cargo-containing vesicles from the corpse phagolysosome was reduced, resulting in delayed cargo degradation and phagolysosome resolution. Thus, by combining ultrastructural studies and sphingolipidomic analysis with observing single phagolysosomes over time, we identified a role of prosaposin/SPP-10 in maintaining phagolysosomal structure, which promotes efficient resolution of phagocytic cargos.
QHR810435_Supplemental_Material_REV3 – Supplemental material for Understanding Decision-Making and Decision Difficulty in Women With an Unintended Pregnancy in the Netherlands
Creators: name: Brauer, Marieke
name: Ditzhuijzen, Jenneke Van
name: Boeije, Hennie
name: Nijnatten, Carolus Van
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, QHR810435_Supplemental_Material_REV3 for Understanding Decision-Making and Decision Difficulty in Women With an Unintended Pregnancy in the Netherlands by Marieke Brauer, Jenneke van Ditzhuijzen, Hennie Boeije and Carolus van Nijnatten in Qualitative Health Research
Nonspecific membrane-matrix interactions influence diffusivity of lipid vesicles in hydrogels
Creators: name: Tam, Nicky W.
name: Schullian, Otto
name: Cipitria, Amaia
name: Dimova, Rumiana
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: membrane-matrix interactions
subject: lipid vesicles
subject: diffusivity
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: The diffusion of extracellular vesicles and liposomes in vivo is affected by different tissue environmental conditions and is of great interest in the development of liposome-based therapeutics and drug-delivery systems. Here, we use a bottom-up biomimetic approach to better isolate and study steric and electrostatic interactions and their influence on the diffusivity of synthetic large unilamellar vesicles in hydrogel environments. Single-particle tracking of these extracellular vesicle-like particles in agarose hydrogels as an extracellular matrix model shows that membrane deformability and surface charge affect the hydrogel pore spaces that vesicles have access to, which determines overall diffusivity. Moreover, we show that passivation of vesicles with PEGylated lipids, as often used in drug-delivery systems, enhances diffusivity, but that this effect cannot be fully explained with electrostatic interactions alone. Finally, we compare our experimental findings with existing computational and theoretical work in the field to help explain the nonspecific interactions between diffusing particles and gel matrix environments.
Supplementary_Tables_1_2 – Supplemental material for Subjective Executive Function Weaknesses Are Linked to Elevated Internalizing Symptoms Among Community Adolescents
Creators: name: Mullin, Benjamin C.
name: Emmaly L. Perks
name: Haraden, Dustin A.
name: Snyder, Hannah R.
name: Hankin, Benjamin L.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Supplementary_Tables_1_2 for Subjective Executive Function Weaknesses Are Linked to Elevated Internalizing Symptoms Among Community Adolescents by Benjamin C. Mullin, Emmaly L. Perks, Dustin A. Haraden, Hannah R. Snyder and Benjamin L. Hankin in Assessment
SOM_1.pdf. – Supplemental material for Fundamental clinical skills of adult cardiopulmonary bypass: results of the 2017 national survey
Creators: name: Searles, Bruce
name: Darling, Edward
name: Riley, Jeffrey
name: Wiles, Jason R.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Cardiology
subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, SOM_1.pdf. for Fundamental clinical skills of adult cardiopulmonary bypass: results of the 2017 national survey by Bruce Searles, Edward Darling, Jeffrey Riley and Jason R. Wiles in Perfusion
Supplemental Material, Appendix_1_-_Patient_Survey_-720601 - Patient and clinician perspectives of an integrated electronic medication prescribing and dispensing system: A qualitative study at a multisite Australian hospital network
Creators: name: Lau, Grace
name: Ho, Jayde
name: Lin, Susan
name: Yeoh, Karen
name: Wan, Tiffany
name: Hodgkinson, Marisa
Publisher: name: SAGE Journals
Year: 2017
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified

description: Supplemental Material, Appendix_1_-_Patient_Survey_-720601 for Patient and clinician perspectives of an integrated electronic medication prescribing and dispensing system: A qualitative study at a multisite Australian hospital network by Grace Lau, Jayde Ho, Susan Lin, Karen Yeoh, Tiffany Wan, and Marisa Hodgkinson in Health Information Management Journal
DS_10.1177_0038040718822573 – Supplemental material for Aspiration Squeeze: The Struggle of Children to Positively Selected Immigrants
Creators: name: Engzell, Per
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Education
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, DS_10.1177_0038040718822573 for Aspiration Squeeze: The Struggle of Children to Positively Selected Immigrants by Per Engzell in Sociology of Education
Online_Appendix_-_Owsiak_-_Fdnts_Dem-Terr_Peace_-_CMPS – Supplemental material for Foundations for integrating the democratic and territorial peace arguments
Creators: name: Owsiak, Andrew P.
Publisher: name: SAGE Journals
Year: 2016
Subjects: subject: 220104 Human Rights and Justice Issues
subject: FOS: Philosophy, ethics and religion
subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, Online_Appendix_-_Owsiak_-_Fdnts_Dem-Terr_Peace_-_CMPS for Foundations for integrating the democratic and territorial peace arguments by Andrew P. Owsiak in Conflict Management and Peace Science
Supplemental Material, ESI - Peptide-coated palladium nanoparticle for highly sensitive bioanalysis of trypsin in human urine samples
Creators: name: Guohua Zhou
name: Huimin Jiang
name: Yanfang Zhou
name: Peilian Liu
name: Yongmei Jia
name: Ye, Cui
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies
subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental Material, ESI for Peptide-coated palladium nanoparticle for highly sensitive bioanalysis of trypsin in human urine samples by Guohua Zhou, Huimin Jiang, Yanfang Zhou, Peilian Liu, Yongmei Jia, and Cui Ye in Nanomaterials and Nanotechnology
Supplemental Material, Summary_Tables_RandR2 - Risk for Mental Disorders Associated With Sexual Assault: A Meta-Analysis
Creators: name: Dworkin, Emily R.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, Summary_Tables_RandR2 for Risk for Mental Disorders Associated With Sexual Assault: A Meta-Analysis by Emily R. Dworkin in Trauma, Violence, & Abuse
Supplemental material for Differences in the Nasal Inflammatory Response to Cynodon dactylon From Rural and Urban Areas in Patients With Allergic Rhinitis
Creators: name: Sánchez, Jorge
name: Sánchez, Andres
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental Material for Differences in the Nasal Inflammatory Response to Cynodon dactylon From Rural and Urban Areas in Patients With Allergic Rhinitis by SánchezJorge MD, MSc, EAC Sánchez Andres Biol, MSc Sánchez Jorge Biol, MSc in Allergy & Rhinology
shaw-supplement – Supplemental material for Urban development-induced displacement and quality of life in Kolkata
Creators: name: Annapurna Shaw
name: Saharan, Tara
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Economics
subject: 120599 Urban and Regional Planning not elsewhere classified
subject: FOS: Social and economic geography

description: Supplemental material, shaw-supplement for Urban development-induced displacement and quality of life in Kolkata by Annapurna Shaw and Tara Saharan in Environment & Urbanization
Computerized cognitive control training to reduce rumination in major depression: A randomized controlled trial
Creators: name: Zetsche, Ulrike
name: Neumann, Pauline
name: Bürkner, Paul-Christian
name: Renneberg, Babette
name: Koster, Ernst H. W.
name: Hoorelbeke, Kristof
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Cognitive control training
subject: Rumination
subject: Major depression
subject: Experience sampling
subject: Ambulatory assessment
subject: 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie

description: Objective Rumination is a major risk factor for the onset and recurrence of depressive episodes and has been associated with deficits in updating working memory content. This randomized controlled trial examines whether training updating-specific cognitive control processes reduces daily ruminative thoughts in clinically depressed individuals. Methods Sixty-five individuals with a current major depressive episode were randomized to 10 sessions of either cognitive control training (N = 31) or placebo training (N = 34). The frequency and negativity of individuals’ daily ruminative thoughts were assessed for seven days before training, after training, and at a 3-month follow-up using experience sampling methodology. Secondary outcomes were depressive symptoms, depressed mood, and level of disability. Results Cognitive control training led to stronger improvements in the trained task than placebo training. However, cognitive control training did not lead to greater reductions in the frequency or negativity of daily ruminative thoughts than placebo training. There were no training-specific effects on participants' depressive symptoms or level of disability. Conclusions The robustness of the present null-findings, combined with the methodological strengths of the study, suggest that training currently depressed individuals to update emotional content in working memory does not affect the frequency or negativity of their daily ruminative thoughts.
Supplemental material for Proximal pulmonary arterial wall disease in patients with persistent pulmonary hypertension after successful left-sided valve replacement according to the hemodynamic phenotype
Creators: name: Domingo, Enric
name: Grignola, Juan C.
name: Trujillo, Pedro
name: Aguilar, Rio
name: Roman, Antonio
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Cardiology
subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: Supplemental Material for Proximal pulmonary arterial wall disease in patients with persistent pulmonary hypertension after successful left-sided valve replacement according to the hemodynamic phenotype by Enric Domingo, Juan C. Grignola, Pedro Trujillo, Rio Aguilar and Antonio Roman in Pulmonary Circulation
Supplemental Material, jspr-16-355-File003 - The association between transition pattern of marital conflict resolution styles and marital quality trajectory during the early years of Chinese marriage
Creators: name: Li, Xiaomin
name: Cao, Hongjian
name: Lan, Jing
name: Ju, Xiaoyan
name: Zheng, Yingxian
name: Chen, Yi
name: Zhou, Nan
name: Fang, Xiaoyi
Publisher: name: SAGE Journals
Year: 2017
Subjects: Communication and Media Studies not elsewhere classified
Psychology not elsewhere classified

description: Supplemental Material, jspr-16-355-File003 for The association between transition pattern of marital conflict resolution styles and marital quality trajectory during the early years of Chinese marriage by Xiaomin Li, Hongjian Cao, Jing Lan, Xiaoyan Ju, Yingxian Zheng, Yi Chen, Nan Zhou, and Xiaoyi Fang in Journal of Social and Personal Relationships
Direct synthesis of acyl fluorides from carboxylic acids using benzothiazolium reagents
Creators: name: Maas, Lilian M.
name: Haswell, Alex
name: Hughes, Rory
name: Hopkinson, Matthew N.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: acyl fluorides
subject: amides
subject: benzothiazolium salts
subject: carboxylic acids
subject: deoxygenative reactions
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: 2-(Trifluoromethylthio)benzothiazolium triflate (BT-SCF3) was used as deoxyfluorinating reagent for the synthesis of versatile acyl fluorides directly from the corresponding carboxylic acids. These acyl fluorides were reacted with amines in a one-pot protocol to form different amides, including dipeptides, under mild and operationally simple conditions in high yields. Mechanistic studies suggest that BT-SCF3 can generate acyl fluorides from carboxylic acids via two distinct pathways, which allows the deoxyfluorinating reagent to be employed in sub-stoichiometric amounts.
Supplemental Material, jspr-16-355-File004 - The association between transition pattern of marital conflict resolution styles and marital quality trajectory during the early years of Chinese marriage
Creators: name: Li, Xiaomin
name: Cao, Hongjian
name: Lan, Jing
name: Ju, Xiaoyan
name: Zheng, Yingxian
name: Chen, Yi
name: Zhou, Nan
name: Fang, Xiaoyi
Publisher: name: SAGE Journals
Year: 2017
Subjects: Communication and Media Studies not elsewhere classified
Psychology not elsewhere classified

description: Supplemental Material, jspr-16-355-File004 for The association between transition pattern of marital conflict resolution styles and marital quality trajectory during the early years of Chinese marriage by Xiaomin Li, Hongjian Cao, Jing Lan, Xiaoyan Ju, Yingxian Zheng, Yi Chen, Nan Zhou, and Xiaoyi Fang in Journal of Social and Personal Relationships
Supplemental Material, jspr-16-355-File005 - The association between transition pattern of marital conflict resolution styles and marital quality trajectory during the early years of Chinese marriage
Creators: name: Li, Xiaomin
name: Cao, Hongjian
name: Lan, Jing
name: Ju, Xiaoyan
name: Zheng, Yingxian
name: Chen, Yi
name: Zhou, Nan
name: Fang, Xiaoyi
Publisher: name: SAGE Journals
Year: 2017
Subjects: Communication and Media Studies not elsewhere classified
Psychology not elsewhere classified

description: Supplemental Material, jspr-16-355-File005 for The association between transition pattern of marital conflict resolution styles and marital quality trajectory during the early years of Chinese marriage by Xiaomin Li, Hongjian Cao, Jing Lan, Xiaoyan Ju, Yingxian Zheng, Yi Chen, Nan Zhou, and Xiaoyi Fang in Journal of Social and Personal Relationships
title: What defines the quantum regime of the free-electron laser?
Creators: name: Kling, Peter
name: Giese, Enno
name: Endrich, Rainer
name: Preiss, Paul
name: Sauerbrey, Roland
name: Schleich, Wolfgang P.
Publisher: name: IOP Publishing
Year: 2024

description: The quantum regime of the free-electron laser (FEL) emerges when the discreteness of the momentum of the electron plays a dominant role in the interaction with the laser and the wiggler field. Motivated by a heuristic phase space approach we pursue two different routes to define the transition from the classical FEL to the quantum domain: (i) standard perturbation theory and (ii) the method of averaging. Moreover, we discuss the experimental requirements for realizing a Quantum FEL and connect them to today's capabilities.
Supplemental Material, jspr-16-355-File006 - The association between transition pattern of marital conflict resolution styles and marital quality trajectory during the early years of Chinese marriage
Creators: name: Li, Xiaomin
name: Cao, Hongjian
name: Lan, Jing
name: Ju, Xiaoyan
name: Zheng, Yingxian
name: Chen, Yi
name: Zhou, Nan
name: Fang, Xiaoyi
Publisher: name: SAGE Journals
Year: 2017
Subjects: Communication and Media Studies not elsewhere classified
Psychology not elsewhere classified

description: Supplemental Material, jspr-16-355-File006 for The association between transition pattern of marital conflict resolution styles and marital quality trajectory during the early years of Chinese marriage by Xiaomin Li, Hongjian Cao, Jing Lan, Xiaoyan Ju, Yingxian Zheng, Yi Chen, Nan Zhou, and Xiaoyi Fang in Journal of Social and Personal Relationships