cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Ireland and the Irish in Post-War British Politics.
Creators: name: Shaw, DJ
Publisher: name: University of Liverpool Repository
Year: 2018

description: Despite the research that has been previously published concerning both the Irish in Britain and Ireland in British politics little of this examines the reaction of the Irish in Britain to events that bring Ireland into British post-war politics. Neither does this work place Ireland within a British context. Whilst some authors have not ignored those in Britain that wish to raise the saliency of Ireland in British politics, most have either reduced it to a few paragraphs or sentences. This is especially true within popular British historiography which dislikes challenges to the many warming myths found within Whig narratives. However, myths concerning the Irish in Britain can be found in Irish historiography as well, such as those concerning the power of Irish voters in Britain. There remains a tendency to look at Irish political activity in post-war Britain in a thin and superficial manner. This study is intended to fill several gaps. It will examine the reaction of the Irish in Britain as it emerges from beneath the surface of British politics. It will look at those groups that attempted to put pressure on successive British Governments even when Ireland was not in the public eye. This will also include those that wanted to protect Northern Ireland’s position within the Union. Another goal of this research is to place Ireland within a wider British context. Previously when the importance of Ireland has increased in British politics, it has been studied within a strictly Irish context. This thesis will show that the British response to Ireland is framed as much by British issues as Irish ones. This research will also seek to debunk some of the myths concerning the Irish vote in Britain, showing that they are a modern European population, making deliberative decisions that reflect this. It will conclude that despite the many myths, Ireland has little political saliency for British politicians and for all but a small section of the Irish population in Britain. The Irish in Britain are a modern, deliberative civic population, not a 5th column ready to rise in the name of Irish nationalism.
Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs
Creators: name: Sun, Wujin
name: Gu, Zhen
name: Wang, Chao
name: Bomba, Hunter N.
name: Ye, Yanqi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The immune system protects the body against a wide range of infectious diseases and cancer by leveraging the efficiency of immune cells and lymphoid organs. Over the past decade, immune cell/organ therapies based on the manipulation, infusion, and implantation of autologous or allogeneic immune cells/organs into patients have been widely tested and have made great progress in clinical applications. Despite these advances, therapy with natural immune cells or lymphoid organs is relatively expensive and time-consuming. Alternatively, biomimetic materials and strategies have been applied to develop artificial immune cells and lymphoid organs, which have attracted considerable attentions. In this review, we survey the latest studies on engineering biomimetic materials for immunotherapy, focusing on the perspectives of bioengineering artificial antigen presenting cells and lymphoid organs. The opportunities and challenges of this field are also discussed.
Trichogonia hassleri Matff.
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Trichogonia
Trichogonia hassleri

description: Trichogonia hassleri Matff.
Distribution: Brazil, Paraguay.
 Source: Roque et al. 2012.
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
The role of emotional arousal in information sharing: a scoping review protocol
Creators: name: Mullins, Emily
name: Searston, Rachel
name: Semmler, Carolyn
name: Wood, Martin
name: Stephens, Rachel
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Cognitive Psychology
subject: Psychology
subject: FOS: Psychology
subject: Social and Behavioral Sciences
subject: emotion
subject: information dissemination

description: The aim of this scoping review is to examine the relationship between emotional arousal and information sharing behavior
Lysolecithin, but not lecithin, improves nutrient digestibility and growth rates in young broilers
Creators: name: Wealleans, A. L.
name: Buyse, J.
name: Scholey, D.
name: Van Campenhout, L.
name: Burton, E.
name: Di Benedetto, M.
name: Pritchard, S.
name: Nuyens, F.
name: Jansen, M.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: 1. The potential of lecithin and lysolecithin to improve lipid digestion and growth performance was investigated in three experiments: 1. an in vitro model that mimics the intestinal conditions of the chick, 2. a digestibility trial with chicks (5–7 days of age), and 3. a performance trial until 21 days of age. 2. In experiment 1, palm oil (PO), palm oil with lecithin (PO+L), and palm oil with lysolecithin (PO+LY) were subjected to in vitro hydrolysis and applied to Caco-2 monolayers to assess lipid absorption. 3. The in vitro hydrolysis rate of triglycerides was higher in PO+LY (k = 11.76 × 103/min) than in either PO (k = 9.73 × 103/min) or PO+L (k = 8.41 × 103/min), and the absorption of monoglycerides and free fatty acids was highest (P < 0.01) for PO+LY. In experiment 2, 90 broilers were assigned to three dietary treatments: a basal diet with 4% palm oil, and the basal diet supplemented with either 250 ppm lecithin or lysolecithin. 4. ATTD of crude fat was higher in broilers supplemented with lysolecithin, but was lower in broilers supplemented with lecithin. DM digestibility and AMEn in birds supplemented with lysolecithin were significantly higher (3.03% and 0.47 MJ/kg, respectively). 5. In experiment 3, 480 broilers were randomly allocated to four dietary treatments: basal diet with soybean oil (2%), basal diet with lecithin (2%), soybean oil diet with 250 ppm lysolecithin, or lecithin oil diet with 250 ppm lysolecithin. 6. Lecithin diets significantly reduced weight at day 10 and 21 compared with soybean oil. However, the addition of lysolecithin to lecithin-containing diets significantly improved bird performance. 7. The results of these studies showed that, in contrast to lecithin, lysolecithin was able to significantly improve the digestibility and energy values of feed in young broilers.
Il "nuovo" mediatore civile e commerciale. Sociogenesi di una professione
Creators: name: Tonarelli, Annalisa
Publisher: name: Cambio. Rivista sulle Trasformazioni Sociali
Year: 2016

description: This article aims to analyze the process of institutionalization of civil and commercial mediation, and in particular to understand how the relationship between mediators and lawyers is configured. What we propose is to frame this process within a dialectic between established and outsiders, but without restricting to (and falling in line with) a search of winners and losers. Our greater interest and our purpose, indeed, is trying to identify the possible configurations assumed by the relations between professions, as a result of the introduction of mandatory mediation in civil justice.
description: Cambio. Rivista sulle Trasformazioni Sociali, Vol. 4 No. 7 (2014)
Managerialismo e professionalismo nei servizi di welfare. La formalizzazione del manager sociale
Creators: name: Castro, Maria Pia
Publisher: name: Cambio. Rivista sulle Trasformazioni Sociali
Year: 2016

description: Researchers agree on the key role played by professions in defining of modern Western States. But the current globalization processes and the changing of the labor market are leading a deep redefinition of the professional systems, Community-oriented. The redefinition processes of welfare services in a managerial way implies several questions concerning the use of a business approach, mainly aimed at maximizing advantages through the efficient use of available resources, in the public field of social services, oriented to promoting social well-being. The paper aims to analyze the professionalization status of the social manager in Italy, through a comparison among several classification systems of occupations (international system - ISCO08, US system – SOC, Italian system - CP2011), for observing the level of homogeneity in the current formalization of the social manager and which are the recurring jobs whose are conferred managerial tasks, at international level.
description: Cambio. Rivista sulle Trasformazioni Sociali, Vol. 4 No. 7 (2014)
Enhancing Nanoparticle Accumulation and Retention in Desmoplastic Tumors via Vascular Disruption for Internal Radiation Therapy
Creators: name: Satterlee, Andrew B.
name: Huang, Leaf
name: Dayton, Paul A.
name: Rojas, Juan D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Aggressive, desmoplastic tumors are notoriously difficult to treat because of their extensive stroma, high interstitial pressure, and resistant tumor microenvironment. We have developed a combination therapy that can significantly slow the growth of large, stroma-rich tumors by causing massive apoptosis in the tumor center while simultaneously increasing nanoparticle uptake through a treatment-induced increase in the accumulation and retention of nanoparticles in the tumor. The vascular disrupting agent Combretastatin A-4 Phosphate (CA4P) is able to increase the accumulation of radiation-containing nanoparticles for internal radiation therapy, and the retention of these delivered radioisotopes is maintained over several days. We use ultrasound to measure the effect of CA4P in live tumor-bearing mice, and we encapsulate the radio-theranostic isotope 177Lutetium as a therapeutic agent as well as a means to measure nanoparticle accumulation and retention in the tumor. This combination therapy induces prolonged apoptosis in the tumor, decreasing both the fibroblast and total cell density and allowing further tumor growth inhibition using a cisplatin-containing nanoparticle.
Integrazione socio-sanitaria e professioni sociali. Quale ruolo per il sociologo? Quale per l'assistente sociale?
Creators: name: Perino, Annamaria
name: Lezzer, Chiara
Publisher: name: Cambio. Rivista sulle Trasformazioni Sociali
Year: 2016

description: The article discusses the issue of integration between the social sector and health sector in the Italian system of services. After stressing the importance of integrated work, we describe the professions involved in the same. Starting from a study carried out on the Italian territory, in the year 2012, we attempt to delineate the role that the sociologist and social worker can play in the achieving the integration between health and social sector. The results suggest that both professionals play important roles in the realization of social-health integration and that, to avoid duplication of responsabilities and functions, it’s necessary, on the one hand, to encourage dialogue and collaboration between these professionals, on the other hand, formalize profiles and skills of the social sector professions.
description: Cambio. Rivista sulle Trasformazioni Sociali, Vol. 4 No. 7 (2014)
Simple non-Abelian extensions of the standard model gauge group and the diboson excesses at the LHC
Creators: name: Cao, Qing-Hong
name: Yan, Bin
name: Zhang, Dong-Ming
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The ATLAS collaboration reported excesses at around 2 TeV in the di-boson production decaying into hadronic final states. We consider the possibility of explaining the excesses with extra gauge bosons in two simple non-Abelian extensions of the Standard Model. One is the so-called $G(221)$ models with a symmetry structure of $SU(2)_1\otimes SU(2)_2\otimes U(1)_X$ and the other is the $G(331)$ models with an extended symmetry of $SU(3)_C\otimes SU(3)_L\otimes U(1)_X$. The $W'$ and $Z'$ bosons emerge after the electroweak symmetry is spontaneously broken. Two patterns of symmetry breaking in the $G(221)$ models are considered in this work: one is $SU(2)_L\otimes SU(2)_2 \otimes U(1)_X \to SU(2)_L\otimes U(1)_Y$, the other is $SU(2)_1\otimes SU(2)_2 \otimes U(1)_Y \to SU(2)_L\otimes U(1)_Y$. The symmetry breaking of the $G(331)$ model is $SU(3)_L\otimes U(1)_X \to SU(2)_L \otimes U(1)_Y$. We perform a global analysis of $W^\prime$ and $Z^\prime$ phenomenology in ten new physics models, including all the channels of $W^\prime/Z^\prime$ decay. Our study shows that the leptonic mode and the dijet mode of $W^\prime/Z^\prime$ decays impose a very stringent bound on the parameter space in several new physics models. Such tight bounds provide a useful guide for building new physics models to address on the diboson anomalies. We also note that the Left-Right and Lepton-Phobic models can explain the $3.4σ$ $WZ$ excess if the $2.6σ$ deviation in the $W^+W^-$ pair around 2~TeV were confirmed to be a fluctuation of the SM backgrounds.
description: Publish version; title changed as suggested by journal Editor
Vernonia parvifolia Cabrera
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Vernonia
Vernonia parvifolia

description: Vernonia parvifolia (Chodat) Cabrera
Distribution: Brazil, Paraguay.
 Source: Cabrera et al. 2009.
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Dalla crisi delle identità professionali moderne all'emergere di nuove esigenze professionali. Il caso dell'ingegnere pedagogico in Francia
Creators: name: Ferrari, Giovannipaolo
Publisher: name: Cambio. Rivista sulle Trasformazioni Sociali
Year: 2016

description: The rise of Internet and the evolution of the ICT allowed to born to new media and new technologies. The latter contributed to the quick change of industrial societies more advanced from the technological point of view. The crisis of professional identities (Dubar 1998; Dubar, Tripier, Boussard 2011; pag. 328) change the way to represent and self-represent the work and the professionalism. The professional practices, nowadays, are more mediated by “machines” that work as “cultural interfaces” (Gane, Beer 2008: 54) in the communication, in the building of meanings and in the management of professional relationships. Workers must use new and unknown work-tools and they need learning and “instrumental genesis” (Rabardel 1995: 161) itinerary: an appropriation itinerary to learn and to be able to use these tools. The new professional practices interact more and more with “things”: the work-tools. The latter, nowadays, often have a technological background that doing “complicated” the human-machine interaction (Latour 1994: 43). In this paper, in conclusion, the author starts from some theoretical anticipations to show the “Pedagogical engineers” case study in French university system.
description: Cambio. Rivista sulle Trasformazioni Sociali, Vol. 4 No. 7 (2014)
Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development
Creators: name: Lin, Ts-Ting
name: Chen, Ling-Hsuan
name: Wu, Anthony Y.
name: Gao, Dong-Yu
name: Chiang, Tsaiyu
name: Chang, Chih-Chun
name: Lai, Charles P.
name: Duda, Dan G.
name: Wang, Jane
name: Lin, Ja-An
name: Chen, Yunching
name: Jin, Pei-Ru
name: Liu, Ya-Chi
name: Ho, Ting-Lun
name: Cheng, Hui-Teng
name: Sung, Yun-Chieh
name: Chao, Po-Han
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Liver damage and fibrosis are precursors of hepatocellular carcinoma (HCC). In HCC patients, sorafenib—a multikinase inhibitor drug—has been reported to exert anti-fibrotic activity. However, incomplete inhibition of RAF activity by sorafenib may also induce paradoxical activation of the mitogen-activated protein kinase (MAPK) pathway in malignant cells. The consequence of this effect in non-malignant disease (hepatic fibrosis) remains unknown. This study aimed to examine the effects of sorafenib on activated hepatic stellate cells (HSCs), and develop effective therapeutic approaches to treat liver fibrosis and prevent cancer development.
Cochain sequences and the Quillen category of a coclass family
Creators: name: Eick, Bettina
name: Green, David J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20D15 (Primary), 20J06 (Secondary)

description: We introduce the concept of an infinite cochain sequence and initiate a theory of homological algebra for them. We show how these sequences simplify and improve the construction of infinite coclass families (as introduced by Eick and Leedham-Green) and how they apply in proving that almost all groups in such a family have equivalent Quillen categories. We also include some examples of infinite families of p-groups from different coclass families that have equivalent Quillen categories.
title: Biologically Inspired Guidance for Autonomous Systems
Creators: name: Topham, Luke
Publisher: name: University of Liverpool Repository
Year: 2020

description: Animals and humans can perform purposeful actions using only their senses. Birds can perch on branches; bats use echolocation to hunt prey and humans are able to control vehicles. It must therefore be possible for autonomous systems to replicate this autonomous behaviour if an understanding of how animals and humans perceive their environment and guide their movements is obtained. Tau theory offers a potential explanation as to how this is achieved in nature. Tau theory posits, that in combination with the so-called ‘motion guides’, animals and humans perform useful movements by closing action-gaps, i.e. gaps between the current state and a desired state. The theory suggests that the variable
Bonamia balansae Hallier f.
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Solanales
Convolvulaceae
Bonamia
Bonamia balansae

description: Bonamia balansae Hallier f.
Distribution: E Bolivia, W Brazil, Paraguay.
 Source: Wood 2013, Jørgensen et al. 2014.
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Avvocati e social media: verso nuove comunità professionali?
Creators: name: Manzo, Cecilia
name: Pais, Ivana
Publisher: name: Cambio. Rivista sulle Trasformazioni Sociali
Year: 2016

description: If in the early days the spread of Internet has been often symbolized by the prefix “e” (e-mails, e-commerce, and so on), we can observe that “we” is emerging as a new keyword. This is because communities have been deeply reshaped by the advent of new communication technologies, social media to begin with. Even traditional professional communities, such as lawyers, changed as the dynamics of interaction started to include he “online” dimension. This article maps the features of such interactions focusing on lawyers, first through the analysis of an original research on the Florence community and then through the analysis of Legalit, the largest digital community of lawyers in Italy. The objective is to show to what extent the new communities present traits similar to the traditional ones (for instance in terms of values and behaviors) notwithstanding very different institutional setups, as well as to map the persisting differences (for instance in terms of membership).
description: Cambio. Rivista sulle Trasformazioni Sociali, Vol. 4 No. 7 (2014)
Webs and the Plebański equation
Creators: name: Krynski, Wojciech
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We consider 3-webs, hyper-para-complex structures and integrable Segre structures on manifolds of even dimension and generalise the second heavenly Plebański equation in the context of higher-dimensional hyper-para-complex structures. We also characterise the Segre structures admitting a compatible hyper-para-complex structure in terms of systems of ordinary differential equations.
title: Characterisation of the first p-type Segmented Inverted-coaxial Germanium Detector, SIGMA
Creators: name: Pearce, Fiona Jane
Publisher: name: University of Liverpool Repository
Year: 2021

description: The Segmented Inverted-coaxial GerMAnium (SIGMA) detector is a large volume High Purity Germanium (HPGe) gamma-ray detector that aims to demonstrate superior en- ergy and position resolution over other large volume segmented germanium detectors. The SIGMA prototype detector is the first p-type detector of its kind to be produced. Due to the low noise of the point contact, the SIGMA detector can provide excellent energy resolution and, through the use of Pulse Shape Analysis (PSA), excellent po- sition resolution. Accurate and precise energy and position determination are the key factors in effective gamma-ray tracking making SIGMA particularly suited for use at Radioactive Ion Beam (RIB) experiments such as DESPEC. The SIGMA prototype detector has been characterised and tested at the Univer- sity of Liverpool. SIGMA showed excellent energy resolution with the point contact achieving 0.89 keV at 122 keV and 2.21 keV at 1332 keV and a relative efficiency of 40.9%. A collimated beam of 241Am and 137Cs gamma rays were scanned across the detector in 1 mm steps to investigate the crystal size, structure and position and the active area of the individual segments. The 241Am data was used to produce a risetime matrix displaying the change in drift time across the front face of the crystal. The detector was also operated alongside BGO detectors in coincidence mode and data acquired using the 137Cs beam to investigate pulse shape behaviour in the crystal at a range of positions. The pulses from all functioning segments were collected, includ- ing both real charge and image charge pulses, and used to produce an average response from each segment for individual x-y-z locations in the crystal. The average pulses were compared to investigate the position response of the detector. A measurable difference in pulse shape was seen in multiple segments for a separation of as little as 2 mm in one dimension.
Determining $V_{tb}$ at Electron-Positron Colliders
Creators: name: Cao, Qing-Hong
name: Yan, Bin
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Verifying $V_{tb} \simeq 1$ is critical to test the three generation assumption of the Standard Model. So far our best knowledge of $V_{tb}$ is inferred either from the $3\times 3$ unitarity of CKM matrix or from single top-quark productions upon the assumption of universal weak couplings. The unitarity could be relaxed in new physics models with extra heavy quarks and the universality of weak couplings could also be broken if the $Wtb$ coupling is modified in new physics models. In this work we propose to measure $V_{tb}$ in the process of $e^+ e^- \to t\bar{t}$ without prior knowledge of the number of fermion generations or the strength of the $Wtb$ coupling. Using an effective Lagrangian approach, we perform a model-independent analysis of the interactions among electroweak gauge bosons and the third generation quarks, i.e. the $Wtb$, $Zt\bar{t}$ and $Zb\bar{b}$ couplings. The electroweak symmetry of the Standard Model specifies a pattern of deviations of the $Z$-$t_L$-$t_L$ and $W$-$t_L$-$b_L$ couplings after one imposes the known experimental constraint on the $Z$-$b_L$-$b_L$ coupling. We demonstrate that, making use of the predicted pattern and the accurate measurements of top-quark mass and width from the energy threshold scan experiments, one can determine $V_{tb}$ from the cross section and the forward-backward asymmetry of top-quark pair production at an {\it unpolarized} electron-positron collider.
description: publish version
L'esperimento in scienza politica: alcuni elementi di critica metodologica
Creators: name: Calò, Cristina
name: Rago, Marina
Publisher: name: Cambio. Rivista sulle Trasformazioni Sociali
Year: 2016

description: This article examines the use of experimental method in political science. In the first part we put in evidence the constitutive principles and the limits of the experimental method. Subsequently we highlight the practical research problems deriving from the transposition of the experimental approach in the domain of human sciences. We offer a brief review of the main fields of political science where the experiment has been adopted. In the second part we analyze three of most famous political experiments: Gosnell’s experiment (1926) on the reasons of electoral abstention; Eldersveld’s experiment (1956) on the effects of propaganda strategies on electoral behavior; Iyengar’s experiment (1982) on television effects of political preferences expressed by media’s users. Each experiment is described in-depth; the critique pinpoints the numerous and serious violations of the classic experimental method, which results totally distorted.
description: Cambio. Rivista sulle Trasformazioni Sociali, Vol. 4 No. 7 (2014)
Aggregation and pressure effects of asphaltene and resin molecules at oil–water interfaces: a coarse-grained molecular dynamics and free energy study
Creators: name: Deetz, Joshua D.
name: Faller, Roland
Publisher: name: Taylor & Francis
Year: 2019
Subjects: Biophysics
Biochemistry
Space Science
Physical Sciences not elsewhere classified
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Coarse-grained molecular dynamics simulations were used to investigate the aggregation of asphaltene and resin molecules in oils and their deposition to oil–water interfaces. Resin, “interfacially-active” asphaltenes, and “bulk-like” asphaltenes are considered as solutes in organic phases consisting of aromatics or saturates. Resins and asphaltenes formed aggregates with a spacing of 0.46 nm between stacked polycyclic sheets. Whether in the aromatic or saturated solvent, resin molecules did not interact with the interface, but its aggregates remained in the bulk. The degree of surface activity of asphaltenes was found to increase with the polarity of their chemical groups, and decrease with the aromatics content of the solvent. Axial stress profiles were measured to calculate the interfacial tension of each system. The tension of interfaces of crude oil with water was found to depend on aromatics content. The free energy of deposition of asphaltenes and resin molecules to the interface was measured using well-tempered metadynamics, in which it was found that “interfacially-active” asphaltenes possess greater stability at the oil-water interface than “bulk-like” asphaltenes, and the organic solvent influences the favorability of deposition.
Ultrasound Molecular Imaging of VEGFR-2 in Clear-Cell Renal Cell Carcinoma Tracks Disease Response to Antiangiogenic and Notch-Inhibition Therapy
Creators: name: Bautch, Victoria L.
name: Chiang, Yun-Chen
name: Rojas, Juan D.
name: Chytil, Anna
name: Dayton, Paul A.
name: Kimryn Rathmell,
name: Chong, Diana C.
name: Lin, Fanglue
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Metastatic clear-cell renal cell carcinoma (ccRCC) affects thousands of patients worldwide each year. Antiangiogenic therapy has been shown to have beneficial effects initially, but resistance is eventually developed. Therefore, it is important to accurately track the response of cancer to different therapeutics in order to appropriately adjust the therapy to maximize efficacy. Change in tumor volume is the current gold standard for determining efficacy of treatment. However, functional variations can occur much earlier than measurable volume changes. Contrast-enhanced ultrasound (CEUS) is an important tool for assessing tumor progression and response to therapy, since it can monitor functional changes in the physiology. In this study, we demonstrate how ultrasound molecular imaging (USMI) can accurately track the evolution of the disease and molecular response to treatment.
Methods, algorithms and computer codes for calculation of electron-impact excitation parameters
Creators: name: Bogdanovich, P.
name: Kisielius, R.
name: Stonys, D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We describe the computer codes, developed at Vilnius University, for the calculation of electron-impact excitation cross sections, collision strengths, and excitation rates in the plane-wave Born approximation. These codes utilize the multireference atomic wavefunctions which are also adopted to calculate radiative transition parameters of complex many-electron ions. This leads to consistent data sets suitable in plasma modelling codes. Two versions of electron scattering codes are considered in the present work, both of them employing configuration interaction method for inclusion of correlation effects and Breit-Pauli approximation to account for relativistic effects. These versions differ only by one-electron radial orbitals, where the first one employs the non-relativistic numerical radial orbitals, while another version uses the quasirelativistic radial orbitals. The accuracy of produced results is assessed by comparing radiative transition and electron-impact excitation data for neutral hydrogen, helium and lithium atoms as well as highly-charged tungsten ions with theoretical and experimental data available from other sources.
description: Lithuan. J. Physics
I villaggi rurali fascisti di Potenza
Creators: name: Morese, Gaetano
Publisher: name: Cambio. Rivista sulle Trasformazioni Sociali
Year: 2016

description: The question of rural villages of Potenza has its roots in the early nineteenth century, involving the urban bourgeoisie in the restoration of the historic center with the displacement of peasants. In the Fascist era, then, the recovery of this policy together with the rural and industrial development programs of the city, led to a new program of construction of rural and mixed (workers/peasants) villages. This operation accentuated the ancient social separation between the bourgeoisie and peasants and between them and the workers also on the spatial plane, and favored the political and social control by the ruling classes, within consolidated mental and social models.
description: Cambio. Rivista sulle Trasformazioni Sociali, Vol. 4 No. 7 (2014)
Therapeutic Drug Monitoring, Electronic Health Records, and Pharmacokinetic Modeling to Evaluate Sirolimus Drug Exposure–Response Relationships in Renal Transplant Patients
Creators: name: Patel, Uptal D.
name: Melloni, Chiara
name: Gonzalez, Daniel
name: Wu, Huali
name: Cohen-Wolkowiez, Michael
name: Jiang, Wenlei
name: Guptill, Jeffrey T.
name: Ku, Lawrence
name: Hornik, Christoph
name: Hill, Kevin
name: Zheng, Nan
name: Greenberg, Rachel
name: Zimmerman, Kanecia O.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Sirolimus, an immunosuppressant agent used in renal transplantation, can prevent allograft rejection. Identification of the therapeutic index (ratio of minimum toxic concentration to minimum therapeutic concentration) for immunosuppresants is necessary to optimize the care of patients and set standards for bioequivalence evaluation of sirolimus products. However, the therapeutic index for sirolimus has been inconsistently defined, potentially due to inconsistencies in sirolimus exposure-response relationships.
Sodium-salt adduct fullerenes prevent self-association and amyloid β fibril formation: molecular dynamics approach
Creators: name: Altamirano, Miguel Angel Balderas
name: Basurto-Islas, Gustavo
name: Martínez-Herrera, Melchor
name: Molina, Juan Luis Pichardo
name: Figueroa-Gerstenmaier, Susana
Publisher: name: Taylor & Francis
Year: 2020
Subjects: Biophysics
Biochemistry
Physical Sciences not elsewhere classified
Cell Biology
Neuroscience
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer

description: Aggregation of amyloid β peptides (AβP) forming fibrils and senile plaques is associated with numerous neurodegenerative disorders such as Alzheimer’s disease (AD). While there is no cure for AD, there is a possibility to retard and prevent the impairment. Inhibiting or interfering the aggregation of Aβ using fullerenes has shown to be a promising strategy to treat AD. The hydrophobic nature of fullerenes compromises its interaction with living cells inducing toxicity; thus, it is necessary to functionalize the molecule promoting its water solubility. In this study, we evaluate the structural and dynamical properties of six diethyl malonate C60 fullerene adducts and its corresponding sodium salts in aqueous solution by molecular dynamics simulations. By means of radial distribution functions, hydrogen bond counting, density profiles, and solvent-accessible surface area, we demonstrate that the sodium malonate fullerene adducts have higher hydration ability while the corresponding diethyl malonate adducts show a hydrophobic tendency, forming self-aggregates. Additionally, we calculate the density profiles of ternary systems including amyloid β peptide 1–42 (AβP42) monomers and found that bis-, tris-, tetra-, and pentaadducts of C60 with disodium malonate addends interact with amyloid molecules, blocking partially their self-aggregation. These data support the understanding of previous reports that indicated the efficiency of sodium malonate fullerene as inhibitors of AβP aggregation. Additionally, we performe measurements in vitro by dynamic light scattering and found that fullerene aggregation is independent of incubation time.
Bonamia subsessilis Hassl.
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Solanales
Convolvulaceae
Bonamia
Bonamia subsessilis

description: Bonamia subsessilis Hassl.
Distribution: S Bolivia, Brazil, Paraguay.
 Source: Wood 2013, Jørgensen et al. 2014.
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Haemosporidian parasite diversity in an under-surveyed Australian avifauna
Creators: name: Hoppe, Ian R.
name: Johnson, Allison E.
name: VanWormer, Elizabeth
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Cancer
subject: 60506 Virology

description: Haemosporidian parasites of birds are geographically widespread, have been detected in a phylogenetically diverse array of hosts, and have been the focus of extensive research due to both their impacts on birds and their similarity to vector-borne diseases of humans. Advances in molecular diagnostic tools have created a greater awareness of the genetic diversity of haemosporidian infections. Yet in spite of their more or less global distribution, comparatively little is known about the haemosporidians affecting birds in Australia. We screened blood from 889 birds (23 species) for haemosporidian blood parasite infections during the 2019 breeding season at Brookfield Conservation Park, South Australia. We examined the genetic (lineage) diversity of haemosporidian infections in this behaviourally and ecologically diverse host assemblage and examined the congruence between parasite and host phylogenies. We identified seven Haemoproteus mitochondrial cytochrome b lineages, five of which were novel. Four birds had simultaneous co-infections by two Haemoproteus lineages each. The Haemoproteus lineages clustered at the host family level. Two Plasmodium lineages were also identified, each of which had been previously detected in different avian host species in Australasia. We did not detect any Leucocytozoon infections in our sample. This study supplies critical baseline data on host–parasite associations in a poorly-surveyed geographic region.
Negotiating Global Chinatowns: Difference, Diversity and Connection
Creators: name: Hing-Yuk Wong, Cindy
name: McDonogh, Gary W.
Publisher: name: Cambio. Rivista sulle Trasformazioni Sociali
Year: 2016

description: Over the past two centuries, diverse and changing Chinatowns have become global enclaves where separation from a surrounding city and society intersects with both the construction of “Chinese” communities and the processes that integrate Chinese into wider contexts while challenging or changing these contexts. Based on a decade of fieldwork in Chinatowns in the Americas, Europe, Australia, Asia and Africa, the investigators highlight the tensions of segregation and communit(ies) through the lenses of physical form and boundaries, social centers, and imagery. Drawing on Henri Lefebvres’s tripartite vision of the social construction of urban spaces (les espaces perçus, conçus and vécus), this article shows that Chinatowns, as distinctive spaces within a city, encapsulate intense debates about place, citizenship, rights and diversity that speak more generally to cities, nations and global urbanism.
description: Cambio. Rivista sulle Trasformazioni Sociali, Vol. 3 No. 6 (2013)
Generation of well relaxed all atom models of stereoregular polymers: a validation of hybrid particle-field molecular dynamics for polypropylene melts of different tacticities
Creators: name: De Nicola, Antonio
name: Munaò, Gianmarco
name: Grizzuti, Nino
name: Auriemma, Finizia
name: De Rosa, Claudio
name: Sevink, Agur
name: Milano, Giuseppe
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: The tacticity of vinyl polymer chains strongly affects the physical properties of polymeric materials, as example the chain conformations and stiffness. In the present work we tested how the hybrid Particle-Field Molecular Dynamics (PF-MD) technique is capable to describe conformational differences of polymer chains as function of the tacticity. In particular, we focus on tacticity effect of atactic, isotactic, and syndiotactic polypropylene (PP) homopolymer melts. We found that PF-MD simulations exhibit dependence of Flory’s Characteristic Ratio from the fraction of racemo diads along the PP chains in qualitative agreement with Small Angle Neutron Scattering (SANS) experiments and theoretical previsions. Finally, we calculated and compared the packing length parameter on very high stereoregular syndiotactic PP systems with rheological measurements. A qualitative agreement between the calculated and experimental packing length is found.
Use of Therapeutic Drug Monitoring, Electronic Health Record Data, and Pharmacokinetic Modeling to Determine the Therapeutic Index of Phenytoin and Lamotrigine
Creators: name: Ku, Lawrence C.
name: Hill, Kevin D.
name: Gonzalez, Daniel
name: Guptill, Jeffrey T.
name: Hornik, Christoph P.
name: Cohen-Wolkowiez, Michael
name: Greenberg, Rachel G.
name: Melloni, Chiara
name: Wu, Huali
name: Berezny, Alysha
name: Zheng, Nan
name: Jiang, Wenlei
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Defining a drug's therapeutic index (TI) is important for patient safety and regulating the development of generic drugs. For many drugs, the TI is unknown. A systematic approach was developed to characterize the TI of a drug using therapeutic drug monitoring and electronic health record (EHR) data with pharmacokinetic (PK) modeling. This approach was first tested on phenytoin, which has a known TI, and then applied to lamotrigine, which lacks a defined TI.
title: Characterisation of High–Performance Electron Sources for Particle Accelerators using a Transverse Energy Spread Spectrometer
Creators: name: Juarez Lopez, David
Publisher: name: University of Liverpool Repository
Year: 2023

description: Electron beams have demonstrated to have the brightness needed to drive free–electron lasers (FEL) at X–ray wavelengths. These state-of-the-art elec- tron beams are now becoming limited by achieving a low mean transverse energy (MTE) at room and cryogenic temperatures of electrons emitted from photo–cathode–based electron sources. Reducing the MTE in an accelerator which drives a FEL delivers a significant reduction in the saturation length for an X–ray FEL, thus reducing the machine’s construction footprint and operating costs whilst increasing X–ray beam brightness. In this thesis I present in detail the commissioning of a transverse energy spread spectrometer (TESS) following substantial upgrades to this system. The commissioning work uses data for single–crystal copper photocathodes illuminated at various wavelengths supported by a comparison to predi- ctions from a sophisticated density–functional theory simulation. Additional data for single–crystal zirconium and niobium is presented at different wave- lengths and temperatures with comparison to simulation values. I also present details of the complete characterisation of a batch of al- kali metal photocathodes grown at CERN and transported to Daresbury to utilise the TESS instrument. This batch comprised three caesium tellurium and one caesium potassium antimony photocathodes grown on high–purity polycrystalline copper substrates via a co-deposition process, none of which had previously been characterised in such detail.
Social organisation and breeding biology of the Western Grasswren (Amytornis textilis textilis)
Creators: name: Vega, Aline Gibson
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Grasswrens (Amytornis) lack behavioural ecological studies despite many species having a declining population and threatened status. The Western Grasswren (Amytornis textilis) is a semi-arid passerine endemic to Western Australia (WA) and South Australia. This study aims to provide further knowledge about the social organisation and breeding biology of the WA subspecies (A. t. textilis) based on a colour-banded population over three years of monitoring. Western Grasswrens maintained territories in pairs, with occasional cooperative breeding facilitated by adult offspring of either sex who delayed dispersal. There was no evidence of divorce between breeding pairs. However, resighting of banded grasswrens was infrequent which may have biased this conclusion. Nest predation and abandonment events were lower than previously documented for this species. Offspring productivity was high, with >70% of the monitored groups producing at least one fledgling per year. Grasswrens used a range of substrates for nesting, but all had common structural features that likely aided in the concealment or thermoregulation of the nest. Social organisation and breeding biology were similar to what had been observed in two other grasswren species. This study has increased our understanding of a poorly understood cryptic species, and understudied genus, that can later be incorporated into future management strategies, population viability models and comparative analysis.
A Systematic Literature Review Approach to Estimate the Therapeutic Index of Selected Immunosuppressant Drugs After Renal Transplantation:
Creators: name: Guptill, Jeffrey T.
name: Hill, Kevin D.
name: Melloni, Chiara
name: Gonzalez, Daniel
name: Zimmerman, Kanecia O.
name: Cohen-Wolkowiez, Michael
name: Wu, Huali
name: Ericson, Jessica E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Drugs that exhibit close margins between therapeutic and toxic blood concentrations are considered to have a narrow therapeutic index (NTI). The Food and Drug Administration has proposed that NTI drugs should have more stringent bioequivalence standards for approval of generic formulations. However, many immunosuppressant drugs do not have a well-defined therapeutic index (TI).
Quartieri privati: stato dell'arte e prospettive di ricerca
Creators: name: Porcu, Manuela
Publisher: name: Cambio. Rivista sulle Trasformazioni Sociali
Year: 2016

description: In recent decades there has been an increasing spread of collective ownership housing: associations or residential communities, private neighborhoods, homeowners associations. Residents of the same neighborhood share spaces and services, ensured by an elective administration and internal revenue for the management. The article aims to provide a framework about this subject. The characteristics of this private form of urbanization will be outlined looking at favorable and adverse arguments. It will show how, in spite of advantages related to an efficient service provision, the spread of private neighborhoods singles out the idea of the city to pursue and involves social costs in terms of segregation and urban fragmentation. This subject, as yet little studied in Italy, can highlight dynamics and processes at work in contemporary cities.
description: Cambio. Rivista sulle Trasformazioni Sociali, Vol. 3 No. 6 (2013)