cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Second Skin Iterations: Programmes and Prototypes
Creators: name: Steed, Josie
name: Fairburn, Sue
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Research paper presented at Futurescan 3: Intersecting Identities, Glasgow School of Art, 11th-12th November 2015.

Futurescan 3: Intersecting Identities
Edited by Helena Britt, Laura Morgan and Kerry WaltonNovember 2015
ISBN: 978 1 911217 08 4
title: Does accelerated long term forgetting occur in patients recently diagnosed with localisation related epilepsy?
Creators: name: Ashe, Marion
Publisher: name: University of Liverpool Repository
Year: 2011

description: Purpose: Memory difficulties are a problem for many people with epilepsy, caused by a variety of factors. Research has identified ‘accelerated long term forgetting’ as a possible cause for discrepancy between subjective and objective memory performance in patients with epilepsy, with research focusing on refractory epilepsy. The aim of this study was to examine the objective and subjective memory performance of patients recently diagnosed with epilepsy, including long term forgetting rates. Methods: Newly diagnosed patients with localisation related epilepsy (n=14), and healthy controls (n=13) matched to age, gender and education level were assessed for intellectual functioning, general memory, subjective memory, and anxiety and depression. Furthermore, they were asked to learn a story and a set of visual scenes to a pre-set criterion level, with recall and recognition of both tested after 30 minutes and after three weeks. Results: Patients and controls did not differ in their performance as measured by general memory score on Weschler Memory Scale (WMS) (p=0.281). However, patients demonstrated significantly impaired retention on the learnt story over 30 minutes (p=0.024) and significantly impaired recall over three weeks (p=0.021), when compared to controls. In the visual scenes test, patients demonstrated impaired initial learning (p=0.018), but once learnt, retained the same amount of information as controls over a 30 min period (p=0.652). However, patients had significantly poorer recall (p=0.002) and increased forgetting rates (p=0.003) after three weeks, which correlated with lifetime number of generalised seizures (p=0.040). Seizures during the three week delay had no relationship to three week forgetting scores. Subjective memory scores did not differ between patients and controls, and were correlated with anxiety but not long term forgetting. Conclusion: Compared to controls, recently diagnosed patients demonstrated impaired delayed recall of a story, and accelerated long term forgetting of a visual scenes task. Caution is needed interpreting these results because of the small numbers, and difficulty accounting for contributing factors to cognitive impairment (such as AED use and pathology). However these are the first results of long term forgetting investigations in recently diagnosed patients, and bring into question the need for memory testing over extended delays.
title: Assessing the responsiveness of the "Challenge of Living with Cystic Fibrosis" questionnaire to change in clinical condition
Creators: name: Dyer, Kiri
Publisher: name: University of Liverpool Repository
Year: 2012

description: Background Cystic Fibrosis is a chronic, life shortening genetic disorder requiring a demanding daily treatment routine to manage, which intensifies during periods of pulmonary exacerbation. Parents are most often the primary carers of children with CF, and so, are responsible for handling the complex demands of the treatment regimen. They are, therefore, are at risk of experiencing caregiver burden, which may be exacerbated when their child becomes unwell. Aim To assess the responsiveness of the Challenge of Living with Cystic Fibrosis Questionnaire (CLCF), a new tool designed to estimate the time and effort involved in caring for a child with CF, to change in a child’s clinical condition, and as a result, its applicability in the clinical setting. Method N=13 parents of children with CF aged ≤13, who were at least one year post diagnosis, completed the CLCF during a period of wellness and a period of pulmonary exacerbation. The number of minutes per day undertaking treatment tasks and the average effort expended in treatment tasks was compared at the two time points. Results There was a correlation between the within person difference in minutes per day and the within person difference in average effort (p=0.024), demonstrating a relationship between the amount of time spent in treatment tasks and the effort taken to complete them. There was a trend for parents to spend a greater amount of time on treatments during the period when their child were unwell compared to when they were well, with a median within person difference of 53 minutes, but this did not reach statistical significance (p=0.07). There was no difference in the average effort expended on treatments between the two time points. These results should be interpreted with caution due to the small sample size. Conclusions This has been a valuable pilot study, demonstrating the ability of the CLCF to collect clinically meaningful data, and in part, demonstrated the responsiveness of the CLCF. The CLCF promises to be a useful clinical tool, however, further work is required to definitively establish the clinical relevance of the CLCF, and confirm the measure’s validity and reliability. It has also provided data on the amount of time parents in this study population spent on treatment tasks for their child. This is of particular importance given the expanding number or treatments available for CF, and the time taken for parents to provide these should be considered when making treatment decisions
Appendix related to: The Retrieved Atmospheric Properties of the Sub-stellar Object VHS 1256 b from Analyzing HST, VLT and JWST Spectra
Creators: name: Lueber, Anna
Publisher: name: Zenodo
Year: 2024

description: This archive contains the Appendix to the publication “The Retrieved Atmospheric Properties of the Sub-stellar Object VHS 1256 b from Analyzing HST, VLT and JWST Spectra” in Astronomy and Astrophysics. 

Author list:

Anna Lueber, Kevin Heng, Brendan P. Bowler, Daniel Kitzmann, Johanna M. Vos, and Yifan Zhou

Paper Abstract:

Motivated by the observed ∼ 30% variations in flux from the L7 dwarf VHS 1256 b, we subjected its time-resolved Hubble Space Telescope (HST) WFC3 spectra (measured in two epochs in 2018 and 2020), as well as medium-resolution Very Large Telescope (VLT) X-shooter and Early Release Science James Webb Space Telescope (JWST) spectra to a suite of both standard Bayesian (nested sampling) and machine-learning (random forest) retrievals. We find that both HST and VLT data require vertically varying abundance profiles of water in order to model the spectra accurately. Despite the large flux variations observed in the HST data, the temporal variability cannot be attributed to a single varying atmospheric property. The retrieved atmospheric quantities are consistent with being invariant across time. However, we find that model grids provide generally poor fits to the measured HST spectra and are unsuitable for quantifying the temporal variability of atmospheric properties. Additionally, our analysis of JWST spectra using model grids indicates consistency in retrieved properties across different wavelength channels. Despite the temporal variability in flux, the retrieved properties between HST and VLT, as well as between HST and JWST, are consistent within the respective posterior uncertainties. Such an outcome bodes well for future retrieval analyses of exoplanetary atmospheres, which are expected to exhibit weaker flux variations.

 

A corresponding URL to the paper will be added as soon as it becomes available.
title: Nanometric oxides for functional materials
Creators: name: Evans, Gary
Publisher: name: University of Liverpool Repository
Year: 2012

description: This thesis describes the synthesis and application of complex metal oxide nanoparticles. The work is focussed on three core areas; the synthesis of CoFe2O4 nanoparticles and their application as CO oxidation catalysts, the controlled assembly of functionalised CoFe2O4 and BaTiO3 nanoparticles and the preparation and characterisation of magnetoelectric composites from chemically-bonded nanoparticle assemblies. Chapter 1 gives an introduction to the history of nanotechnology, recent developments in the synthesis of nanoparticles and other areas key to the work described herein. In Chapter 2 details the synthetic and analytical techniques employed. Chapter 3 describes the synthesis and characterisation of CoFe2O4 nanoparticles, and their application as catalysts in the CO oxidation reaction. Nanoparticles were prepared with a range of controlled sizes and were found to be active CO oxidation catalysts. Analysis of their size-dependent activity and stability is performed. Chapter 4 describes the assembly of CoFe2O4 and BaTiO3 nanoparticles by direct functionalisation of the nanoparticle surfaces using complementary organic functional molecules. Characterisation of the functionalised nanoparticles and assemblies is performed, and the extensibility of the developed functionalisation and assembly protocol is tested using particles with different sizes and morphologies. In Chapter 5 the assembled nanoparticles discussed in Chapter 4 are processed into dense ceramics with a view to preparing magnetoelectric composites. The magnetoelectric properties are tested, and optimisation of the ceramics is performed by modification of the starting nanoparticle sizes, composite composition and processing conditions. The composites are tested against control samples prepared by traditional grinding and firing, and characterisation of the ceramics using XRD and electron microscopy provides and insight as to why their magnetoelectric properties differ to those prepared by the traditional technique. The work contained in this thesis has been published in the following papers: - G. Evans, I. V. Kozhevnikov, E. F. Kozhevnikova, J. B. Claridge, R. Vaidhyanathan, C. Dickinson, C. D. Wood, A. I. Cooper, M. J. Rosseinsky, “Particle-size Activity Relationship for CoFe2O4 Nanoparticle CO Oxidation Catalysts,” J. Mater. Chem. 2008, 18, 5518. G. Evans, G. V. Duong, M. J. Ingleson, Z. Xu, J. T. A. Jones, Y. Z. Khimyak, J. B. Claridge, M. J. Rosseinsky, “Chemical Bonding Assembly of Multifunctional Oxide Nanocomposites,” Adv. Funct. Mater. 2010, 20, 231.
The Banner as Representation of Identity and Community
Creators: name: Raeside-Elliott, Fiona
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Research paper presented at Futurescan 3: Intersecting Identities, Glasgow School of Art, 11th-12th November 2015.

Futurescan 3: Intersecting Identities
Edited by Helena Britt, Laura Morgan and Kerry WaltonNovember 2015
ISBN: 978 1 911217 08 4
title: Making the best of it: an emerging grounded theory of caring for an older person with mental health problems
Creators: name: Dodd, Lydia
Publisher: name: University of Liverpool Repository
Year: 2011

description: Aim This study aims to develop a substantive grounded theory of the informal care of older people with acute functional mental health problems in the community, using data from qualitative interviews with informal carers and classic grounded theory methodology. Results The theory presented is based on field notes and memos from in depth interviews conducted with 11 informal carers of people aged 65 and over with a functional mental illness. The participants include carers of people with depression and anxiety (n=8), bipolar disorder (n=2) and schizophrenia (n=1). Many of the people cared for also had physical co-morbidities. Most patients had longstanding mental illnesses with equally longstanding caring arrangements. The age range of carers was 40 to 93 years, and of patients was 65 to 88 years. Five of the carers were female, and six male. Eight patients were female, and three male. Carers were related to patients as husband (n=5), wife (n=3), daughter (n=2) or son (n=1). Most carers lived with the person they cared for (n=9). The theory explains, predicts and interprets how carers of older people with longstanding functional mental health problems who have received mental health service input attempt to resolve the tensions that they face as part of caring through making the best of it. Making the best of it consists of three inter-related dimensions: aspirational optimization, adjustment and keeping going. Aspirational optimization is the carer’s desire for the best for the person they care for, and their desire to do their best for them. The six aspects of adjustment are dependency adjustment, identity adjustment, expectation adjustment, illness adjustment, adjustment resourcing and balancing priorities. Making the best of it explains how many carers of older people with longstanding functional mental health problems who have received mental health service input continue to live with unresolved tensions, keeping going despite the fluctuating demands placed upon them, while carrying out corresponding adjustments, which are resourced internally and externally. Making the best of it is discussed in relation to the concepts of family burden, coping, obligation, adaptation and identity. The theory shows how carers of older people with longstanding functional mental health problems who have received mental health service input manage the challenges and the rewards that accompany caring on a daily basis in the decisions, sacrifices and prioritizations they make. It is useful for health and social care practitioners and researchers, as well as contributing to the body of extant classic grounded theories.
'Smocking is Evil?' Unpicking and Rebinding
Creators: name: Bicknell, Les
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Research paper presented at Futurescan 3: Intersecting Identities, Glasgow School of Art, 11th-12th November 2015.

Futurescan 3: Intersecting Identities
Edited by Helena Britt, Laura Morgan and Kerry WaltonNovember 2015
ISBN: 978 1 911217 08 4
Direct observation of nanoscale interface phase in the superconducting chalcogenide K$_{x}$Fe$_{2-y}$Se$_2$ with intrinsic phase separation
Creators: name: Ricci, A.
name: Poccia, N.
name: Joseph, B.
name: Innocenti, D.
name: Campi, G.
name: Zozulya, A.
name: Westermeier, F.
name: Schavkan, A.
name: Coneri, F.
name: Bianconi, A.
name: Takeya, H.
name: Mizuguchi, Y.
name: Takano, Y.
name: Mizokawa, T.
name: Sprung, M.
name: Saini, N. L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We have used scanning micro x-ray diffraction to characterize different phases in superconducting K$_{x}$Fe$_{2-y}$Se$_2$ as a function of temperature, unveiling the thermal evolution across the superconducting transition temperature (T$_c\sim$32 K), phase separation temperature (T$_{ps}\sim$520 K) and iron-vacancy order temperature (T$_{vo}\sim$580 K). In addition to the iron-vacancy ordered tetragonal magnetic phase and orthorhombic metallic minority filamentary phase, we have found a clear evidence of the interface phase with tetragonal symmetry. The metallic phase is surrounded by this interface phase below $\sim$300 K, and is embedded in the insulating texture. The spatial distribution of coexisting phases as a function of temperature provides a clear evidence of the formation of protected metallic percolative paths in the majority texture with large magnetic moment, required for the electronic coherence for the superconductivity. Furthermore, a clear reorganization of iron-vacancy order around the T$_{ps}$ and T$_c$ is found with the interface phase being mostly associated with a different iron-vacancy configuration, that may be important for protecting the percolative superconductivity in K$_{x}$Fe$_{2-y}$Se$_2$.
description: 6 pages, 4 figures
Futurescan 3: Intersecting Identities - Acknowledgements
Creators: name: Figshare Admin Futurescan
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Acknowledgements for Futurescan 3: Intersecting Identities, Glasgow School of Art, 11th-12th November 2015.

Futurescan 3: Intersecting Identities
Edited by Helena Britt, Laura Morgan and Kerry WaltonNovember 2015
ISBN: 978 1 911217 08 4
Epidemiologic Studies of Cyclospora cayetanensis in Guatemala
Creators: name: Bern, Caryn
name: Klein, Robert E.
name: Venczel, Linda
name: Hernandez, Beatriz
name: Alvarez de Mejia, Maricruz
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: In 1996 and 1997, cyclosporiasis outbreaks in North America were linked to eating Guatemalan raspberries. We conducted a study in health-care facilities and among raspberry farm workers, as well as a case-control study, to assess risk factors for the disease in Guatemala. From April 6, 1997, to March 19, 1998, 126 (2.3%) of 5, 552 surveillance specimens tested positive for Cyclospora; prevalence peaked in June (6.7%). Infection was most common among children 1.5 to 9 years old and among persons with gastroenteritis. Among 182 raspberry farm workers and family members monitored from April 6 to May 29, six had Cyclospora infection. In the case-control analysis, 62 (91%) of 68 persons with Cyclospora infection reported drinking untreated water in the 2 weeks before illness, compared with 88 (73%) of 120 controls (odds ratio [OR] 3.8, 95% confidence interval [CI] 1.4, 10.8 by univariate analysis). Other risk factors included water source, type of sewage drainage, ownership of chickens or other fowl, and contact with soil (among children younger than 2 years).
Spots on Am stars
Creators: name: Balona, L. A.
name: Catanzaro, G.
name: Abedigamba, O. P.
name: Ripepi, V.
name: Smalley, B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We investigate the light variations of 15 Am stars using four years of high-precision photometry from the Kepler spacecraft and an additional 14 Am stars from the K2 Campaign 0 field. We find that most of the Am stars in the Kepler field have light curves characteristic of rotational modulation due to star spots. Of the 29 Am stars observed, 12 are δ Scuti variables and one is a γ Doradus star. One star is an eclipsing binary and another was found to be a binary from time-delay measurements. Two Am stars show evidence for flares which are unlikely to be due to a cool companion. The fact that 10 out of 29 Am stars are rotational variables and that some may even flare strongly suggests that Am stars possess significant magnetic fields. This is contrary to the current understanding that the enhanced metallicity in these stars is due to diffusion in the absence of a magnetic field. The fact that so many stars are δ Scuti variables is also at odds with the prediction of diffusion theory. We suggest that a viable alternative is that the metal enhancement could arise from accretion.
description: 12 pages, 13 figures
New Disinfection and Sterilization Methods
Creators: name: Rutala, William
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: New disinfection methods include a persistent antimicrobial coating that can be applied to inanimate and animate objects (Surfacine), a high-level disinfectant with reduced exposure time (ortho-phthalaldehyde), and an antimicrobial agent that can be applied to animate and inanimate objects (superoxidized water). New sterilization methods include a chemical sterilization process for endoscopes that integrates cleaning (Endoclens), a rapid (4-hour) readout biological indicator for ethylene oxide sterilization (Attest), and a hydrogen peroxide plasma sterilizer that has a shorter cycle time and improved efficacy (Sterrad 50).
title: Polymer routes toward designing gold nanostructures
Creators: name: Schaeffer, Nicolas
Publisher: name: University of Liverpool Repository
Year: 2011

description: The formation of small metallic particles has been intensively investigated in the last few decades because of the unique properties that they exhibit on the nanometer scale. A handful of reliable and straightforward synthetic procedures are used routinely for their manufacture. The most widely applied procedures are variations of the Turkevich–Frens citrate reduction route that allow the manufacture of water–soluble, relatively monodisperse particles in the c.a. 5 to 50 nm range, or the Brust–Shiffrin method that leads, after reduction of a gold precursor in a two phases liquid/liquid system, to the formation of hydrophobic nanoparticles in the c.a. 3 to 8 nm. However, the controlled manufacture of well–defined water–soluble particles in the sub 5 nm scale is still challenging, and most of the reported methods for their preparation involve multip–step preparation or cumbersome size separation procedure, adding costly and time consuming stages to the synthesis. Thus, a simple, robust protocol for the gramscale preparation of uniform colloidal gold below 5 nm is of broad practical value. Herein, the synthesis of near monodisperse gold nanoparticles using series of watersoluble polymeric ligands containing a thiol and/or a thioether is described. The size of the so–formed particles can be adjusted between one and five nanometres by varying the polymer/gold ratio and the colloidal suspensions are stable in aqueous conditions because of the nature of their polymeric protective monolayer. Those polymeric structures have been optimized to control the growth of the particles, leading to an unprecedented narrow size distribution. The near monodispersity of the particles, their stability in aqueous conditions, and their one–pot synthesis all make this method an attractive and versatile synthetic route. Furthermore, in extending the size–range tunability of some of those polymer stabilized gold nanoparticles to the sub 2 nm range, a transition between non–fluorescent and fluorescent nanoparticles is observed. This photophysical property is clearly size–dependant and fluorescence switching is detected for polymer-stabilized gold clusters below 1.7 nm in size. Detailed characterization indicates that the most fluorescent nanomaterial has a 3% quantum yield and is related to the presence of 1.1 nm gold core and a 6.9 nm hydrodynamic radius gold clusters and is not due to a polymer effect, or to the formation of a gold(I) complex.
Human and Canine Pulmonary Blastomycosis, North Carolina, 2001–2002
Creators: name: MacCormack, J. Newton
name: MacDonald, Pia D.M.
name: Langley, Rick L.
name: Gerkin, Susan R.
name: Torok, Michelle R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: We investigated a cluster of blastomycosis in 8 humans and 4 dogs in a rural North Carolina community. Delayed diagnosis, difficulty isolating Blastomyces dermatitidis in nature, and lack of a sensitive and specific test to assess exposure make outbreaks of this disease difficult to study.
Two-dimensional conformal field theory and the butterfly effect
Creators: name: Roberts, Daniel A.
name: Stanford, Douglas
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study chaotic dynamics in two-dimensional conformal field theory through out-of-time order thermal correlators of the form $\langle W(t)VW(t)V\rangle$. We reproduce bulk calculations similar to those of [1], by studying the large $c$ Virasoro identity block. The contribution of this block to the above correlation function begins to decrease exponentially after a delay of $\sim t_* - \fracβ{2π}\log β^2E_w E_v$, where $t_*$ is the scrambling time $\fracβ{2π}\log c$, and $E_w,E_v$ are the energy scales of the $W,V$ operators.
description: v1: 14 pages plus appendices, 2 figures. v2: references updated and minor changes to the text. v3: minor error corrected in Appendix B, but the conclusion is unchanged
Med-CORDEX Baseline Runs: Contributing Institutes and Models
Creators: name: Somot, Samuel
Publisher: name: Zenodo
Year: 2022
Subjects: RCM Med-CORDEX list model institute

description: List of the contributing institutes, contact points, coupled Regional Climate System Models and their status used for the Med-CORDEX Baseline Runs, phase 1, 2 and 3.
 Phase 1 and phase 2 correspond to the first phase of CORDEX.
 Phase 3 corresponds to the CORDEX-CMIP6 initiative.
 Note that contrary to most of the CORDEX RCMs, the Med-CORDEX models are full-coupled ocean-atmosphere RCMs.
 Some models also includes river coupling, ocean biogeochemistry or interactive aerosols.
Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum , Cambodia
Creators: name: Maguire, Jason D.
name: Alker, Alisa P.
name: Shah, Naman K.
name: Sem, Rithy
name: Duong, Socheat
name: Wongsrichanalai, Chansuda
name: Meshnick, Steven R.
name: Muth, Sinuon
name: Ariey, Frederic
name: Susanti, Agustina Ika
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: We conducted surveillance for multidrug-resistant Plasmodium falciparum in Cambodia during 2004–2006 by assessing molecular changes in pfmdr1. The high prevalence of isolates with multiple pfmdr1 copies found in western Cambodia near the Thai border, where artesunate–mefloquine therapy failures occur, contrasts with isolates from eastern Cambodia, where this combination therapy remains highly effective.
title: The origin and role of uterine natural killer cells in patients with recurrent implantation failure
Creators: name: Khan, Leena
Publisher: name: University of Liverpool Repository
Year: 2012

description: Recurrent implantation failure (RIF) is the failure of the embryo to implant. Embryonic causes of RIF have been studied intensely; recently, investigations of endometrial causes of RIF have emerged. ‘Natural Killer’ cells appear in large numbers in the endometrium towards the mid-secretory phase, during the ‘window of impanation’. Their role in recurrent implantation failure needs investigating. There are two competing hypotheses regarding the origin of uNK cells. They are either the result of proliferation of resident uNK cells or are from the trafficking of peripheral blood cells into the uterus and their subsequent differentiation into their uNK form. Endometrial biopsies from 19 patients, 10 ‘low’ density uNK and 9 ‘high’ density uNK were stained using immunohistochemisty to compare antibodies associated with trafficking: L-Selectin, with a marker for peripheral blood NK cells, CD16, against makers for proliferation Ki67 and differentiation NKp30, on endometrial tissue, using CD56 as the universal marker for natural killer cells. The endometrial tissue will be obtained 7 days after the LH surge in the luteal phase as this is the window of implantation. Variation in location of these cells within samples was also studied in the following areas: sub-epithelial, areas with low stromal density and perivascular stroma in both groups. Differences in percentage cell density was observed between both groups, as expected. With both groups observing more positively stained cells of each antibody in perivascular areas. Few numbers of CD62-L and CD16+, markers for trafficking cells were detected. This suggests that uNK cells are not migrating in from peripheral blood, but arising from the endometrium, possibly from heamatopoietic cells. CD56+ cells were seen in higher in areas around vessels than in other locations (p=0.003). Their close proximity to vessels enables them to promote vasculature development. The markers for proliferation and differentiation of uNK cells, Ki67 and NKp30 was also significantly higher in areas around vessels compared to areas near epithelium (p=0.006 and p=0.023 respectively). Perhaps this early development of arteries leads to a highly oxygenated state, which is detrimental to the developing embryo. The paucity of trafficking markers indicates that uNK cells are not trafficking from the peripheral blood, so peripheral blood testing is of no clinical value in patients with recurrent implantation failure. The consistent perivascular location of these cells indicates that these proliferating and differentiating cells have a role in vascular remodelling, which, may lead to a highly oxygenated state, decreasing the receptivity of the endometrium and causing implantation failure.
title: Immunopathology of Complex Regional Pain Syndrome
Creators: name: Osborne, Scott
Publisher: name: University of Liverpool Repository
Year: 2014

description: Both increased mast cells numbers and raised immune mediator concentrations indicate immune activation in the affected skin of patients with early CRPS, but little is known about regional immune cell involvement in late stage CRPS. The aim of the current study was to determine skin immune cell populations in longstanding CRPS. Using 6mm skin punch biopsies from CRPS-affected and non-affected tissues, and a combination of chemical and immunofluorescence staining, we examined the density and function of key cell populations including mast cells, epidermal Langerhans cells (LCs), and tissue resident T-cells. We found no significant differences in either overall immune cell infiltrates, or mast cell density between CRPS-affected and non-affected sub-epidermal tissue sections, contrasting recent findings in early CRPS by other groups. However, CD1a+ LC densities in the epidermal layer were significantly decreased in affected compared to non-affected CRPS limbs (p =
Severe Dengue Epidemics in Sri Lanka, 2003–2006
Creators: name: Kanakaratne, Nalaka
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: One-sentence summary for table of contents: Changes in transmission dynamics and virus genes are likely increasing emergence of severe epidemics in this country.Recent emergence of dengue hemorrhagic fever in the Indian subcontinent has been well documented in Sri Lanka. We compare recent (2003–2006) and past (1980–1997) dengue surveillance data for Sri Lanka. The 4 dengue virus (DENV) serotypes have been cocirculating in Sri Lanka for >30 years. Over this period, a new genotype of DENV-1 has replaced an old genotype. Moreover, new clades of DENV-3 genotype III viruses have replaced older clades. Emergence of new clades of DENV-3 in 1989 and 2000 coincided with abrupt increases in the number of reported dengue cases, implicating this serotype in severe epidemics. In 1980–1997, most reported dengue cases were in children. Recent epidemics have been characterized by many cases in children and adults. Changes in local transmission dynamics and genetic changes in DENV-3 are likely increasing emergence of severe dengue epidemics in Sri Lanka.
title: The roles of the cockle Cerastoderma edule L. on ecosystem functioning: cockle comings and goings
Creators: name: Cesar, Christopher
Publisher: name: University of Liverpool Repository
Year: 2011

description: There is increasing interest regarding the impacts of human activities on the functioning of marine systems. A primary driver of change to marine systems is through the impacts of fishing. Biomass-dominant target species have the potential to mediate a number of ecosystem functions, either directly or indirectly, through the influences that taxa have on ecological processes and/or other biotic or abiotic components of the system. This thesis investigates the roles of the cockle, Cerastoderma edule on ecosystem functioning within intertidal sedimentary systems. A series of investigations revealed that cockles have the potential to mediate benthic primary productivity through their roles in the recycling of nutrients and effects of sediment structure and have impacts upon assemblage biomass and functional diversity. However, the roles of cockles on other aspects of ecological functioning were less apparent. An investigation also assessed the suitability of the use of assigning taxa to functional groups when assessing functional diversity. Taxa were shown to have the potential to change their feeding activity following disturbance, with evidence suggesting a change to benthic-pelagic coupling. This change however, would not have been observed with investigations of functional traits alone and thus supports the use of direct measures of functions to support functional trait diversity measures. It is imperative for ecological investigations to consider long-term changes to population dynamics. However, particularly in marine systems, such data are generally lacking. This thesis presents a novel approach, using information from sea fisheries reports to gain a semi-quantitative 30-year data set on cockle landings within Morecambe Bay, north-west England. This technique revealed evidence of temporal changes to the functional processes at a large scale. This thesis provides evidence for cockles acting as key contributors to ecological functioning. The functional role of cockles is tempered by the high degree of redundancy within these assemblages, highlighting a number of issues relating to the use of field studies and encouraging a move towards increased use of traditional ecology in future studies.
Risk Factors for and Estimated Incidence of Community-associated Clostridium difficile Infection, North Carolina, USA 1
Creators: name: Sena, Arlene C.
name: Woods, Christopher W.
name: McDonald, L. Clifford
name: Benoit, Stephen R.
name: Evans, Sharon
name: Naggie, Susanna
name: Engel, Jeffery
name: Kutty, Preeta K.
name: Frederick, Joyce
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Antimicrobial drug exposure is the most common modifiable risk factor for infection.We determined estimated incidence of and risk factors for community-associated Clostridium difficile infection (CA-CDI) among patients treated at 6 North Carolina hospitals. CA-CDI case-patients were defined as adults (>18 years of age) with a positive stool test result for C. difficile toxin and no hospitalization within the prior 8 weeks. CA-CDI incidence was 21 and 46 per 100,000 person-years in Veterans Affairs (VA) outpatients and Durham County populations, respectively. VA case-patients were more likely than controls to have received antimicrobial drugs (adjusted odds ratio [aOR] 17.8, 95% confidence interval [CI] 6.6–48] and to have had a recent outpatient visit (aOR 5.1, 95% CI 1.5–17.9). County case-patients were more likely than controls to have received antimicrobial drugs (aOR 9.1, 95% CI 2.9–28.9), to have gastroesophageal reflux disease (aOR 11.2, 95% CI 1.9–64.2), and to have cardiac failure (aOR 3.8, 95% CI 1.1–13.7). Risk factors for CA-CDI overlap with those for healthcare-associated infection.
A notion of effectiveness for subshifts on finitely generated groups
Creators: name: Aubrun, Nathalie
name: Barbieri, Sebastián
name: Sablik, Mathieu
Publisher: name: arXiv
Year: 2014
Subjects: subject: Group Theory (math.GR)
subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37B10, 03D10, 20F10

description: We generalize the classical definition of effectively closed subshift to finitely generated groups. We study classical stability properties of this class and then extend this notion by allowing the usage of an oracle to the word problem of a group. This new class of subshifts forms a conjugacy class that contains all sofic subshifts. Motivated by the question of whether there exists a group where the class of sofic subshifts coincides with that of effective subshifts, we show that the inclusion is strict for several groups, including recursively presented groups with undecidable word problem, amenable groups and groups with more than two ends. We also provide an extended model of Turing machine which uses the group itself as a tape and characterizes our extended notion of effectiveness. As applications of these machines we prove that the origin constrained domino problem is undecidable for any group of the form $G \times \mathbb{Z}$ subject to a technical condition on $G$ and we present a simulation theorem which is valid in any finitely generated group.
Med-CORDEX Baseline Runs: Contributing Institutes and Models
Creators: name: Somot, Samuel
Publisher: name: Zenodo
Year: 2023
Subjects: RCM Med-CORDEX list model institute

description: List of the contributing institutes, contact points, coupled Regional Climate System Models and their status used for the Med-CORDEX Baseline Runs, phase 1, 2 and 3.
 Phase 1 and phase 2 correspond to the first phase of CORDEX.
 Phase 3 corresponds to the CORDEX-CMIP6 initiative.
 Note that contrary to most of the CORDEX RCMs, the Med-CORDEX models are full-coupled ocean-atmosphere RCMs.
 Some models also includes river coupling, ocean biogeochemistry or interactive aerosols.
title: Uncertainty associated with the measurement of airborne sound insulation in the field
Creators: name: Whitfield, William
Publisher: name: University of Liverpool Repository
Year: 2014

description: Understanding uncertainty is an important part of any scientific measurement process and the ability to evaluate and understand uncertainty is a requirement of the International Standards for quality control. The basic uncertainties relating to the measurement of airborne sound insulation in the field can be assessed using the methods in BS5725. However, identifying the components that contribute to the total variability is beyond the scope of the standard and more detailed information requires a more advanced approach. Recent developments in the “Guide to the expression of uncertainty in measurement” (GUM) suggest an approach can be used where identification of the input variables and their likely contribution will result in a solution that can be modelled providing enough information is available. However, recent research on uncertainty in sound insulation using GUM has identified problems involving the correlation between frequency bands, which leads to an overestimate of uncertainty. An empirical approach is used in this thesis, which incorporates advanced analysis of variance (ANOVA) and a specific model called Gauge Repeatability and Reproducibility (GRR). It enables the components of variance in the measurement system to be partitioned and provides an estimate of their contribution. In addition, ANOVA highlights any interaction between factors. In the GRR, carried out on a lightweight timber floor and a heavyweight concrete floor, significant interaction was detected between the operator and part. Good agreement is obtained in the repeatability and reproducibility calculated for each construction and the samples are combined with measurements of test elements that provide a wider range of sound insulation performance. The uncertainty associated with the instrumentation, operator, interaction and part are calculated in each case. It is shown that the interaction component is important and should be contained in any approach evaluating uncertainty. Further evidence reveals that the total uncertainty in the measurement process is dependent on the construction being measured.
Regulatory Capital Modelling for Credit Risk
Creators: name: Rutkowski, Marek
name: Tarca, Silvio
Publisher: name: arXiv
Year: 2014
Subjects: subject: Risk Management (q-fin.RM)
subject: FOS: Economics and business

description: The Basel II internal ratings-based (IRB) approach to capital adequacy for credit risk plays an important role in protecting the Australian banking sector against insolvency. We outline the mathematical foundations of regulatory capital for credit risk, and extend the model specification of the IRB approach to a more general setting than the usual Gaussian case. It rests on the proposition that quantiles of the distribution of conditional expectation of portfolio percentage loss may be substituted for quantiles of the portfolio loss distribution. We present a more economical proof of this proposition under weaker assumptions. Then, constructing a portfolio that is representative of credit exposures of the Australian banking sector, we measure the rate of convergence, in terms of number of obligors, of empirical loss distributions to the asymptotic (infinitely fine-grained) portfolio loss distribution. Moreover, we evaluate the sensitivity of credit risk capital to dependence structure as modelled by asset correlations and elliptical copulas. Access to internal bank data collected by the prudential regulator distinguishes our research from other empirical studies on the IRB approach.
description: Updated figures and references to theorems/laws, as well as general editing to tighten the prose. arXiv admin note: text overlap with arXiv:1412.0064
Completeness of Communicable Disease Reporting, North Carolina, USA, 1995–1997 and 2000–2006
Creators: name: Maillard, Jean-Marie
name: Weber, David J.
name: Poole, Charles
name: MacDonald, Pia D.M.
name: Sickbert-Bennett, Emily E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Reporting proportions were <50% for 49 of the 53 diseases evaluated.Despite widespread use of communicable disease surveillance data to inform public health intervention and control measures, the reporting completeness of the notifiable disease surveillance system remains incompletely assessed. Therefore, we conducted a comprehensive study of reporting completeness with an analysis of 53 diseases reported by 8 health care systems across North Carolina, USA, during 1995–1997 and 2000–2006. All patients who were assigned an International Classification of Diseases, 9th Revision, Clinical Modification, diagnosis code for a state-required reportable communicable disease were matched to surveillance records. We used logistic regression techniques to estimate reporting completeness by disease, year, and health care system. The completeness of reporting varied among the health care systems from 2% to 30% and improved over time. Disease-specific reporting completeness proportions ranged from 0% to 82%, but were generally low even for diseases with great public health importance and opportunity for interventions.
Adaptive confidence bands for Markov chains and diffusions: Estimating the invariant measure and the drift
Creators: name: Söhl, Jakob
name: Trabs, Mathias
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics
subject: 62G15 (Primary), 60F05, 60J05, 60J60, 62M05 (Secondary)

description: As a starting point we prove a functional central limit theorem for estimators of the invariant measure of a geometrically ergodic Harris-recurrent Markov chain in a multi-scale space. This allows to construct confidence bands for the invariant density with optimal (up to undersmoothing) $L^{\infty}$-diameter by using wavelet projection estimators. In addition our setting applies to the drift estimation of diffusions observed discretely with fixed observation distance. We prove a functional central limit theorem for estimators of the drift function and finally construct adaptive confidence bands for the drift by using a completely data-driven estimator.
description: to appear in ESAIM: Probability and Statistics
Comparison of Tranexamic Acid plus Intramuscular Oxytocin with Intramuscular Oxytocin alone for prophylaxis of Primary Postpartum Haemorrhage in vaginal delivery
Creators: name: Singh, Sukanya
name: Dr Surekha Atul Tayade
Publisher: name: Zenodo
Year: 2023
Subjects: postpartum hemorrhage, prevention, tranexamic acid, vaginal delivery, maternal mortality

description: In contemporary obstetrics, postpartum hemorrhage is one of the primary causes of maternal mortality. Postpartum hemorrhage is defined as blood loss of more than 500 mL within the first 24 hours of birth. The term, late postpartum hemorrhage is used when the bleeding lasts more than 24 hours. Due to the physiological changes that occur during pregnancy, the body may sustain a 500 mL blood loss without experiencing any severe negative consequences. However, even a modest amount of blood loss might be harmful in cases of comorbidities like anemia. However, even a modest amount of blood loss might be harmful in cases of comorbidities like anemia. Postpartum hemorrhage poses a double threat because it decreases the mother's strength and immunity, leaving her more vulnerable to puerperal illnesses. Second, the loss of blood could be fatal. Maternal death occurs gradually as a result of constant trickle-like blood loss. There are predictors which may help us in scrutinizing patients to be labeled as high risk for postpartum hemorrhage, however, there are no formulized criteria for postpartum hemorrhage. The active management of the third stage of labor is a management protocol made to prevent as well as manage this potentially life-threatening condition. It has significantly led to a reduction in maternal mortality rates. However, with more permutation - combinations of medical management and using different pharmacological agents we can devise a better algorithm for further deduction in the mortality rates. Here we propose to randomly allocate and administer an additional drug, tranexamic acid, in addition to uterotonics prophylactically given during the active management of the third stage of labor in vaginal deliveries. In doing so we compare the differences between groups in which only oxytocin was given and in which oxytocin plus tranexamic acid was given.
description: {"references": ["1.\tWorld Health Organization. Managing complications in pregnancy and childbirth. Geneva: World Organization; 2000.", "2.\tKramer MS, Berg C, Abenhaim H, Dahhou M, Rouleau J, Mehrabadi A, et al. Incidence, risk factors, and temporal trends in severe postpartum hemorrhage. Am J Obstet Gynecol. 2013;209:449.e1\u20137.", "3.\tBateman BT, Berman MF, Riley LE, Leffert LR. The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries. Anesth Analg. 2010;110:1368\u201373.", "4.\tMathai M, G\u00fclmezoglu AM, Hill S. Saving womens lives: Evidence-based recommendations for the prevention of postpartum haemorrhage. Bull World Health Organ. 2007;85:322\u20133.", "5.\tMcCormick ML, Sanghvi HCG, Kinzie B, McIntosh N. Preventing postpartum hemorrhage in low-resource settings. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet. 2002;77:267\u201375."]}
New Dengue Virus Type 1 Genotype in Colombo, Sri Lanka
Creators: name: Logendra, Barathy
name: Gunasena, Sunethra
name: Abeysinghe, M.R. Nihal
name: Gubler, Duane
name: Margolis, Harold
name: Tan, Ying
name: Amarasinghe, Ananda
name: Palihawadana, Paba
name: De Silva, Aruna
name: Wahala, Wahala
name: de Silva, Aravinda
name: Tissera, Hasitha
name: Tam, Clarence
name: Letson, G. William
name: Ooi, Eng
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The number of cases and severity of disease associated with dengue infection in Sri Lanka has been increasing since 1989, when the first epidemic of dengue hemorrhagic fever was recorded. We identified a new dengue virus 1 strain circulating in Sri Lanka that coincided with the 2009 dengue epidemic.
Stitched Together - Community Learning, Collaborative Making
Creators: name: Maughan, Hannah
name: Hackney, Fiona
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Research paper presented at Futurescan 3: Intersecting Identities, Glasgow School of Art, 11th-12th November 2015.

Futurescan 3: Intersecting Identities
Edited by Helena Britt, Laura Morgan and Kerry WaltonNovember 2015
ISBN: 978 1 911217 08 4