cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Experiences of violence before and during pregnancy and adverse pregnancy outcomes: An analysis of the Canadian Maternity Experiences Survey
Creators: name: Urquia, Marcelo L.
name: O’Campo, Patricia J.
name: Heaman, Maureen I.
name: Janssen, Patricia A.
name: Thiessen, Kellie R.
Publisher: name: BioMed Central
Year: 2015

description: Background: Abuse and violence against women constitute a global public health problem and are particularly important among women of reproductive age. The literature is not conclusive regarding the impact of violence against pregnant women on adverse pregnancy outcomes, such as preterm birth, small for gestational age and postpartum depression. Most studies have been conducted on relatively small samples of high-risk women. Our objective was to investigate what dimensions of violence against pregnant women were associated with preterm birth, small for gestational age and postpartum depression in a nationally representative sample of Canadian women. Methods We analysed data of the Maternity Experiences Survey, a nationally representative survey of Canadian women giving birth in 2006. The comprehensive questionnaire included a 19-item section to collect information on different dimensions of abuse and violence, such as type, frequency, timing and perpetrator of violence. The survey design is a stratified simple random sample from the 2006 Canadian Census sampling frame. Participants were 6,421 biological mothers (78% response rate) 15 years and older who gave birth to a singleton live birth and lived with their infant at the time of the survey. Logistic regression was used to compute Odds Ratios. Survey weights were used to obtain point estimates and 95% confidence intervals were obtained with the jacknife method of variance estimation. Covariate control was informed by use of directed acyclic graphs. Results No statistically significant associations were found for preterm birth or small for gestational age, after adjustment. Most dimensions of violence were associated with postpartum depression, particularly the combination of threats and physical violence starting before and continuing during pregnancy (Adjusted Odds Ratio = 4.1, 95% confidence interval: 1.9, 8.9) and perpetrated by the partner (4.3: 2.1, 8.7). Conclusions Our findings provide weak evidence of an association between experiences of abuse before and during pregnancy and preterm birth and small for gestational age but they indicate that several dimensions of abuse and violence are consistently associated with postpartum depression.
title: Risk factors for chylothorax and persistent serous effusions after congenital heart surgery
Creators: name: Heyn, Anna Gertraud
Publisher: name: Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
Year: 2025
Subjects: subject: Cardiac insufficiency; Cardiac surgery; Chylothorax; Congenital heart disease; Persistent effusions; Risk factor.
subject: DDC Classification::6 Technik, Medizin, angewandte Wissenschaften::61 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objectives: This study evaluated the various risk factors for chylothorax and persistent serous effusions (>7 days) after congenital heart surgery and developed equations to calculate the probability of their occurrence. Methods: We performed a retrospective review of different medical databases at the University Hospital of Erlangen between January 2014 and December 2016. Full model regression analysis was used to identify risk factors, and prediction algorithms were set up to calculate probabilities. Discriminative power of the models was checked with the help of C-statistics. Results: Of 745 operations on 667 patients, 68 chylothoraxes (9.1%) and 125 persistent pleural effusions (16.8%) were diagnosed. Lowest temperature [P = 0.043; odds ratio (OR) 0.899], trisomy 21 (P = 0.001; OR 5.548), a higher vasoactive inotropic score on the day of surgery (P = 0.001; OR 1.070) and use of an assist device (P = 0.001; OR 5.779) were significantly associated with chylothorax. Risk factors for persistent serous effusions were a given or possible involvement of the aortic arch during the operation (P = 0.000; OR 3.982 and 2.905), univentricular hearts (P = 0.019; OR 2.644), a higher number of previous heart operations (P = 0.014; OR 1.436), a higher vasoactive inotropic score 72 h after surgery (P = 0.019; OR 1.091), a higher central venous pressure directly after surgery (P = 0.046; OR 1.076) and an aortic cross-clamp time >86 min (P = 0.023; OR 2.223), as well as use of an assist device (P = 0.002; OR 10.281). The prediction models for both types of effusions proved to have excellent discriminative power. Conclusions: Persistent serous effusion is associated with a higher vasoactive inotropic score 72 h after surgery, an aortic cross-clamp time >86 min and elevated central venous pressure directly after surgery, which, in combination, potentially indicate cardiac stress. The developed logistic algorithm helps to estimate future likelihood.
Paisajes contestados: un acercamiento a la dimensión geográfica de la protesta social en la Bogotá del siglo XXI
Creators: name: Delgado Rozo, Juan David
name: Gamba Amaya, Isabel
Publisher: name: Universidad Externado de Colombia. Facultad de Ciencias Sociales y Humanas. Centro de Investigaciones sobre Dinámica Social (CIDS). Área de Investigación en Cultura y Sociedad
Year: 2024
Subjects: subject: Movimientos de protesta - Bogotá (Colombia)
subject: Movimientos sociales - Bogotá (Colombia)
subject: Acción reivindicatoria – Colombia
subject: Paro Nacional
subject: Protesta social
subject: Movilización social
subject: Bogotá
subject: Geografía simbólica
subject: Densidad política

description: En este artículo queremos explorar la dimensión geográfica de la protesta social a luz de la experiencia de la Paro Nacional que se llevó a cabo en Bogotá en noviembre y diciembre de 2019. Nos proponemos realizar una aproximación a las formas diversas en que el acto de protestar se relaciona con el espacio y en particular con la ciudad, partiendo de considerar que esta relación puede abordase en dos niveles. El primero, tiene que ver con el abordaje de la protesta social como un fenómeno que tiene un comportamiento espacial específico, es decir, presenta distribuciones, localizaciones y patrones espaciales que pueden ser seguidos, analizados y cartografiados, permitiendo así responder preguntas como: ¿dónde se desarrollan las protestas y por qué lo hacen dónde lo hacen? ¿cuál es el flujo o sentido de las marchas y qué sendas se utilizan? ¿por qué se protesta más en algunos lugares que en otros?
description: In this article, we aim to explore the geographical dimension of social protest in light of the experience of the National Strike that took place in Bogotá in November and December 2019. We intend to approach the diverse ways in which the act of protesting relates to space and, in particular, to the city, considering that this relationship can be addressed on two levels. The first level concerns the approach to social protest as a phenomenon with specific spatial behavior, meaning it presents distributions, locations, and spatial patterns that can be tracked, analyzed, and mapped. This allows us to answer questions such as: where do protests occur and why do they happen where they do? What is the flow or direction of the marches and which routes are used? Why is there more protesting in some places than in others?
Marketing mix factors that influence to decision buying's cultural products of tourist in Nakhonpathom province
Creators: name: Kiatisuk Ichayanan
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University.
Year: 2014
Subjects: Marketing mix cultural products Kao-Lam

description: Journal of Management Science Nakhon Pathom Rajabhat University, 1, 2, 30-41
title: Neuartige Aufbau-, Verbindungs- und Integrationstechniken zur Realisierung heterogener Millimeterwellensysteme
Creators: name: Pfahler, Tim
Publisher: name: Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
Year: 2025
Subjects: subject: DDC Classification::6 Technik, Medizin, angewandte Wissenschaften::62 Ingenieurwissenschaften
subject: DDC Classification::6 Technik, Medizin, angewandte Wissenschaften::62 Ingenieurwissenschaften::620 Ingenieurwissenschaften und zugeordnete Bereiche

description: Die Erforschung und Weiterentwicklung integrierter Halbleitertechnologie ermöglicht die Realisierung hochperformanter technischer Systeme in den Bereichen Millimeterwellen (mmW)-Messtechnik, Sensorik und Kommunikation mit Systembandbreiten von über 100 GHz bis in den dreistelligen GHz-Frequenzbereich. Mithilfe der Aufbau-, Verbindungs- und Integrationstechnologie werden Einzelfunktionalitäten von mmW-Bauelementen, wie integrierte Halbleiterbausteine oder mmW-Substrate, zu einem heterogenen mmW-System verschaltet und somit eine Systemfunktionalität realisiert. In dieser Arbeit wurden neuartige Aufbau-, Verbindungs- und Integrationstechniklösungen, welche die Verschaltung und Integration von Teilkomponenten zu einem Gesamtsystem ermöglichen und so die Realisierung zukünftiger heterogener mmW-Systeme eröffnen, erforscht. Die vorliegende Arbeit unterteilt sich in drei Forschungsbeiträge, in denen sowohl die Erforschung von ultrabreitbandigen mmW-Signalschnittstellen über Übertragungsbandbreiten von 130 GHz als auch die Erarbeitung einer vertikalen Wafer-Level Packagearchitektur mit zugehörigem Antennenmodul für den Frequenzbereich von 300 GHz erfolgt. In den zugrunde liegenden Forschungsarbeiten werden die bisher bestehenden Limitierungen in der Aufbau-, Verbindungs- und Integrationstechnik hinsichtlich der Übertragungsbandbreite, der Einfügedämpfung und der Integration von Packageantennen eliminiert und drei für die Systemperformanz entscheidende Signalschnittstellenlösungen präsentiert. Im Rahmen dieser kumulativen Dissertation erfolgte die Konzeptionierung, der Aufbau sowie die messtechnische Verifizierung der zugrunde liegenden mmW-Signalschnittstellen und Packageantennenmodule, wodurch der Nachweis ihrer Funktionalität vorliegt. Durch den Vergleich zu bisher veröffentlichten Ansätzen in Bezug auf die Aufbaukomplexität, die Übertragungsbandbreite und die Einfügedämpfung wird der wissenschaftliche Mehrwert der zugrunde liegenden wissenschaftlichen Publikationen verdeutlicht. Die vorgestellten Lösungen in der Aufbau-, Verbindungs- und Integrationstechnik eröffnen die Implementierung hochperformanter ultrabreitbandiger heterogener mmW-Systeme und System-in-Package-Architekturen in den Anwendungsfeldern ultrabreitbandiger mmW-Messtechnik, drahtloser Sensorik- und Kommunikationslösungen.
Vulnerabilidad y generatividad en familias y su relación con las prácticas institucionales en el territorio de Chía (Cundinamarca). Una experiencia de investigación y formación
Creators: name: Bernal Sánchez, Tatiana Marcela
name: Estupiñán Mojica, Jairo Gustavo
name: Rodríguez Charry, Diana María
Publisher: name: Universidad Externado de Colombia. Facultad de Ciencias Sociales y Humanas. Centro de Investigación de Dinámicas Sociales. Área de Investigación sobre Estudios de Familia
Year: 2023
Subjects: subject: Ecología social
subject: Familia - Aspectos sociales
subject: Familia - Investigaciones - Chía (Cundinamarca, Colombia)
subject: Familia
subject: Ecología social
subject: Redes

description: Los estudios de familia, fueron el punto de confluencia para estudios interdisciplinarios en las ciencias sociales, donde estudiantes e investigadores abordado en la familia como sujeto social, colectivo y político que se gesta en interacciones con la vida natural, social y psicológica. El libro da cuenta del modelo y enfoque investigativo, cuyo ordenamiento epistemológico y paradigmático, de orden complejo, sistémico y ecológico, permitió indagar y transformar procesos, contextos y co-evolucion es a través de un enfoque metodológico de investigación-intervención, que mostró ser virtuoso al permitir adelantar de forma consistente procesos de formación, de creación de conocimiento y de intervención. En contextos diversos, como alcaldías, municipios, cárceles o programas de atención, se observó la configuración de ecologías para la familias y sus miembros, donde la institucionalidad juega un papel preponderante en la atención de problemas de diferente raingambre; la incorporación de las necesidades humanas a lo largo de la vida, nutridas en el entramado relacional, mostró que facilita tanto el desempeño institucional y profesional, la generatividad familiar como la adaptación individual.
MPEC 2024-V66 : 2024 VC1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 VC1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: CHIR99021 Promotes hiPSC-Derived Cardiomyocyte Proliferation in Engineered 3D Microtissues
Creators: name: Hesselbarth, Ramona
Publisher: name: Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
Year: 2025
Subjects: subject: Tissue Engineering
subject: CHIR99021
subject: Proliferation
subject: hiPSC-Kardiomyozyten
subject: DDC Classification::6 Technik, Medizin, angewandte Wissenschaften

description: Cardiac tissue engineering is a promising strategy to generate human cardiac tissues for modeling cardiac diseases, screening for therapeutic drugs, and repairing the injured heart. Yet, several issues remain to be resolved including the generation of tissues with high cardiomyocyte density. Here, it is shown that the integration of the glycogen synthase kinase-3β inhibitor CHIR99021 in collagen I hydrogels promotes proliferation of human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) post-fabrication improving contractility of and calcium flow in engineered 3D cardiac microtissues. CHIR99021 has no effect on the gelation kinetics or the mechanical properties of collagen I hydrogels. Analysis of cell density and proliferation based on Ki-67 staining indicates that integration of CHIR99021 together with external CHIR99021 stimulation increases hiPSC-CM number by ≈2-fold within 7 days post-fabrication. Analysis of the contractility of engineered cardiac tissues after another 3 days in the absence of external CHIR99021 shows that CHIR99021-induced hiPSC-CM proliferation results in synchronized calcium flow, rhythmic beating, increased speed of contraction and contraction amplitude, and reduced peak-to-peak time. The CHIR99021-stimulated engineered cardiac microtissues exhibit spontaneous rhythmic contractions for at least 35 days. Collectively, the data demonstrate the potential of induced cardiomyocyte proliferation to enhance engineered cardiac microtissues by increasing cardiomyocyte density.
Post-discharge management following hip fracture - get you back to B4: A parallel group, randomized controlled trial study protocol
Creators: name: Cook, Wendy L.
name: Khan, Karim
name: Bech, Michelle H.
name: Brasher, Penelope M.
name: Brown, Roy A.
name: Bryan, Stirling
name: Donaldson, Meghan G.
name: Guy, Pierre
name: Hanson, Heather M.
name: Leia, Cheryl
name: Macri, Erin M.
name: Sims-Gould, Joanie
name: McKay, Heather Anne, 1954-
name: Ashe, Maureen C.
Publisher: name: BioMed Central
Year: 2015

description: Background: Fall-related hip fractures result in significant personal and societal consequences; importantly, up to half of older adults with hip fracture never regain their previous level of mobility. Strategies of follow-up care for older adults after fracture have improved investigation for osteoporosis; but managing bone health alone is not enough. Prevention of fractures requires management of both bone health and falls risk factors (including the contributing role of cognition, balance and continence) to improve outcomes. Methods/Design This is a parallel group, pragmatic randomized controlled trial to test the effectiveness of a post-fracture clinic compared with usual care on mobility for older adults following their hospitalization for hip fracture. Participants randomized to the intervention will attend a fracture follow-up clinic where a geriatrician and physiotherapist will assess and manage their mobility and other health issues. Depending on needs identified at the clinical assessment, participants may receive individualized and group-based outpatient physiotherapy, and a home exercise program. Our primary objective is to assess the effectiveness of a novel post-discharge fracture management strategy on the mobility of older adults after hip fracture. We will enrol 130 older adults (65 years+) who have sustained a hip fracture in the previous three months, and were admitted to hospital from home and are expected to be discharged home. We will exclude older adults who prior to the fracture were: unable to walk 10 meters; diagnosed with dementia and/or significant comorbidities that would preclude their participation in the clinical service. Eligible participants will be randomly assigned to the Intervention or Usual Care groups by remote allocation. Treatment allocation will be concealed; investigators, measurement team and primary data analysts will be blinded to group allocation. Our primary outcome is mobility, operationalized as the Short Physical Performance Battery at 12 months. Secondary outcomes include frailty, rehospitalizations, falls risk factors, quality of life, as well as physical activity and sedentary behaviour. We will conduct an economic evaluation to determine health related costs in the first year, and a process evaluation to ascertain the acceptance of the program by older adults, as well as clinicians and staff within the clinic. Trial registration number ClinicalTrials.gov: NCT01254942
Relationship between quality of life, organizational culture, and work effectiveness of personnel in group of general administration under Nakhon Pathom Public Health Office.
Creators: name: Kanisorn Pornkrainet
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University.
Year: 2014
Subjects: quality of life
organizational culture
work effectiveness

description: Journal of Management Science Nakhon Pathom Rajabhat University, 1, 2, 42-55
Protección jurídica de las rondas hídricas en Colombia y su relevancia en el contexto de la frontera agrícola nacional para el sector agropecuario
Creators: name: García Pachón, María Del Pilar
name: Correa Medina, Jaime Augusto
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Uso de la tierra rural - Aspectos económicos - Colombia
subject: Medio ambiente - Aspectos jurídicos - Colombia
subject: Derecho ambiental – Colombia
subject: Ecología agrícola - Aspectos jurídicos - Colombia
subject: Rondas hídricas
subject: UAF
subject: Planificación
subject: Acotamiento
subject: Frontera agrícola nacional
subject: Medio ambiente
subject: Agua

description: Las rondas hídricas son instrumentos multifuncionales que contribuyen a la protección de los cuerpos de agua, favorecen la reducción de impactos generados por la actividad antrópica en las fuentes hídricas y ofrecen un parámetro regulatorio en la determinación de los usos del suelo y su estabilización. Han surtido un proceso técnico y normativo evolutivo en Colombia para efectos de su definición, acotamiento y relevancia tanto para el derecho ambiental como para la gestión de otros sectores, entre ellos, el agropecuario. Fruto de la necesidad de uso y conservación racional de los recursos para las generaciones presentes y futuras hacia las cuales se vierte el concepto de desarrollo sostenible, la importancia de las rondas hídricas ha cobrado relevancia en los procesos de acceso a tierras dotadas bajo la unidad agrícola familiar y por ende juega un papel medular en la planificación sectorial e interrelación entre el sector ambiental y el sector agropecuario, identificando los espacios jurídicos que intersecan uno y otro en la toma de decisiones de adjudicación de cara a la frontera agrícola nacional.
description: The riparian corridors are multifunctional instruments that contribute to the protection of bodies of water, favor the reduction of the impacts of anthropic activity on water sources, as well as offer a regulatory parameter in the determination of land uses and their stabilization. They have undergone an evolutionary technical and regulatory process in Colombia for the purposes of its definition, delimitation, and relevance both for environmental law and for the management of other sectors, including agriculture. As a result of the need for the rational use and conservation of resources for present and future generations towards which the concept of sustainable development is directed, the importance of riparian corridors has gained relevance in the processes of access to land endowed under the Family Agricultural Unit and therefore, plays a key role in sectoral planning and interrelation between the environmental sector and the agricultural sector, identifying the legal spaces that intersect one and the other in decision-making regarding the adjudication of the national agricultural frontier.
title: Modelling of Multi-Stage Internal Loop Air Lift Bioreactor Utilizing Computational Fluid Dynamics
Creators: name: Ramonet Marques, Fernando
name: Haddadi Sisakht, Bahram
name: Bösenhofer, Markus
name: Harasek, Michael
Publisher: name: TU Wien
Year: 2023
Subjects: Computational fluid dynamics
Hydrodynamics
Multi-stage air lift bioreactor
OpenFOAM®

description: In this study, Computational Fluid Dynamics (CFD) is utilized to compare the hydrodynamics of internal loop air lift bioreactors with three different internal configurations. This CFD study compares how splitting the draft tube into multiple stages affects the hydrodynamics of an airlift bioreactor. An in-house Lagrangian particles coupling utility is integrated into an Eulerian solver to evaluate the residence time distribution in each circulation loop. The results showed that the single draft tube geometry maintains a constant downcomer velocity, while the double-stage and triple-stage geometries have higher downcomer velocities on the top section and a more stable downcomer velocity, respectively. Higher recirculation rates can be obtained on the triple-stage reactor configuration. Overall, these findings provide valuable insights for the optimization and design of internal loop air lift bioreactors for various biological applications.
title: Biegen von endlosfaserverstärkten thermoplastischen Verbundrohren
title: Bending of continuous fibre reinforced thermoplastic tubes
titleType: AlternativeTitle
Creators: name: Böcking, Jan
Publisher: name: Universitätsbibliothek Siegen
Year: 2024
Subjects: subject: 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten
subject: CFRTP
subject: Faserverbundrohr
subject: Rotationszugbiegen
subject: Formmechanismen
subject: Faserverlagerung
subject: Composite tube
subject: Rotary draw bending
subject: Forming mechanisms
subject: Fibre relocation

description: In dieser Arbeit wird ein Verfahren entwickelt, um endlosfaserverstärkte thermoplastische Verbundrohre zu biegen. Das Verfahren umfasst das Aufheizen, Formen, Rekonsolidieren und Abkühlen des Verbundrohrs. Grundlagenversuche und Biegeversuche liefern Erkenntnisse zur Umorientierung der Verstärkungsfasern während des Biegens. Diese Ergebnisse fließen in ein kinematisches Modell ein, das den resultierenden Faserwinkel im gebogenen Rohr beschreibt und durch Messdaten validiert wird.
description: In this thesis, a process is developed to bend continuous fiber-reinforced thermoplastic composite pipes. The process includes heating, forming, reconsolidation and cooling of the composite tube. Basic material tests and bending tests provide insights into the reorientation of the reinforcing fibers during bending. These results are incorporated into a kinematic model that describes the resulting fiber angle in the bent tube and is validated by measurement data.
Report or Manuscript on new e.-m. devices for protein-specific sorter
Creators: name: Grillo, Vincenzo
name: Rotunno, Enzo
name: Roncaglia, Alberto
name: Belsito, Luca
Publisher: name: Zenodo
Year: 2020
Subjects: Q-sort
proteins

description: The aim of this deliverable is to explain the strategy and actual realization of a protein specific phase element for the identification of protein.
 The guidelines for this deliverable arise from the theory deliverable as exposed in D3.2 “Manuscript for paper or report on theory advances/test on diagonalisation of operator through coordinate transformation”. An intermediate approach was given in D3.3 “Short report on new hologram on protein-specific sorter” based on hologram but it is obvious that a lossless approach based on fields is much more advisable for protein.
Distance matters: a population based study examining access to maternity services for rural women
Creators: name: Grzybowski, Stefan
name: Stoll, Kathrin
name: Kornelsen, Jude, 1965-
Publisher: name: BioMed Central
Year: 2016

description: Background: In the past fifteen years there has been a wave of closures of small maternity services in Canada and other developed nations which results in the need for rural parturient women to travel to access care. The purpose of our study is to systematically document newborn and maternal outcomes as they relate to distance to travel to access the nearest maternity services with Cesarean section capabililty. Methods: Study population is all women carrying a singleton pregnancy beyond 20 weeks and delivering between April 1, 2000 and March 31, 2004 and residing outside of the core urban areas of British Columbia. Maternal and newborn data was linked to specific geographic catchments by the B.C. Perinatal Health Program. Catchments were stratified by distance to nearest maternity service with Cesarean section capabililty if greater than 1 hour travel time or level of local service. Hierarchical logistic regression was used to test predictors of adverse newborn and maternal outcomes. Results: 49,402 cases of women and newborns resident in rural catchments were included. Adjusted odds ratios for perinatal mortality for newborns from catchments greater than 4 hours from services was 3.17 (95% CI 1.45-6.95). Newborns from catchments 2 to 4 hours, and 1 to 2 hours from services generated rates of 179 and 100 NICU 3 days per thousand births respectively compared to 42 days for newborns from catchments served by specialists. Conclusions: Distance matters: rural parturient women who have to travel to access maternity services have increased rates of adverse perinatal outcomes.
Factors influencing adoption of agro-ecological pest management options for mango fruit fly under information constraints: a two-part fractional regression approach
Creators: name: Owili, Sulman Olieko
name: Otieno, David Jakinda
name: Chimoita, Evans Ligare
name: Baijukya, Frederick Philbert
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Ecology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: The catalytic effect of climate change on the emergence and prevalence of invasive alien pests along with weak pesticide regulatory frameworks in developing countries calls for a transition towards sustainable pest management. Agro-ecological pest management (APM) offers a nature-based, cost-effective alternative for addressing systemic pest challenges, such as mango fruit fly invasion. We applied a two-part fractional regression to sequentially model APM adoption and intensity decisions among 423 smallholder mango orchard managers from Makueni County, Kenya. Despite APM’s potential, we observed moderate adoption rates (56.7%), with the average adopter implementing only 25% of the APM practices concurrently. Farmers’ socio-psychological attributes significantly influenced both adoption and intensity decisions. While perceptions of technology attributes and institutional and social factors primarily influenced both the adoption and intensity decisions, information constraints, resource endowment, gender and inter-generational factors significantly influenced only the intensity decision. To support the transition from synthetic insecticides to APM measures, policymakers should create more opportunities for awareness creation, training and knowledge co-creation and co-production, particularly through social networks and gender-disaggregated participatory group approaches.
Does generation benefit learning for narrative and expository texts? A direct replication attempt
Creators: name: Schindler, Julia
name: Richter, Tobias
name: Mar, Raymond A.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: expository texts
subject: generation effect
subject: learning
subject: narrative texts
subject: replication
subject: 300 Sozialwissenschaften::370 Bildung und Erziehung::370 Bildung und Erziehung

description: Generated information is better recognized and recalled than information that is read. This generation effect has been replicated several times for different types of material, including texts. Perhaps the most influential demonstration is by McDaniel, Einstein, Dunay, and Cobb (Journal of Memory and Language, 1986, 25(6), 645–656; henceforth MEDC). This group tested whether the generation effect occurs only if the generation task stimulates cognitive processes not already stimulated by the text. Numerous studies, however, report difficulties replicating this text by generation-task interaction, which suggests that the effect might only be found under conditions closer to the original method of MEDC. To test this assumption, the present study closely replicated MEDC's Experiment 2 in two separate German and English-speaking samples. The present study provided partial evidence in favor of the expected interaction, which ultimately depended on successful completion of the generation task (with near-to-perfect accuracy). Moreover, it indicates that sentence unscrambling might enhance learning across genres.
Social media and amblyopia: evaluating content and intent on Instagram
Creators: name: McCord, Sarah
name: Ngo, Angela
name: Kraus, Courtney L.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Science Policy

description: Introduction: Social media is a widely-used avenue for the public to find health information. In particular, Instagram is a popular social media platform among adults who may have children within the amblyogenic age range, and it may be used to find amblyopia-related information. The purpose of this study is to assess the quality of the amblyopia information on Instagram. Methods: The top 200 publicly available Instagram posts about amblyopia from October to December 2022 were reviewed and scored using the Currency, Reliability, Authority, and Purpose (CRAP) test. Results: A quarter of posts were from healthcare providers (ophthalmologists, optometrists, opticians), and only 3% of posts were specifically from pediatric ophthalmologists. Most posts, however, were from businesses (51%), which were of lower quality than posts by providers. Discussion: Instagram represents a tremendous opportunity to educate the public. Better utilizing this resource may allow medical professionals to broadly spread accurate, unbiased data.
Effects of atorvastatin metabolites on induction of drug‐metabolizing enzymes and membrane transporters through human pregnane X receptor
Creators: name: Hoffart, E.
name: Ghebreghiorghis, L.
name: Nussler, A. K.
name: Thasler, W. E.
name: Weiss, Thomas S.
name: Schwab, M.
name: Burk, O.
Publisher: name: Universität Regensburg
Year: 2011
Subjects: subject: 610 Medizin

description: Abstract

BACKGROUND AND PURPOSE Atorvastatin metabolites differ in their potential for drug interaction because of differential inhibition of drug-metabolizing enzymes and transporters. We here investigate whether they exert differential effects on the induction of these genes via activation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR).

EXPERIMENTAL APPROACH Ligand binding to PXR or CAR was analysed by mammalian two-hybrid assembly and promoter/reporter gene assays. Additionally, surface plasmon resonance was used to analyse ligand binding to CAR. Primary human hepatocytes were treated with atorvastatin metabolites, and mRNA and protein expression of PXR-regulated genes was measured. Two-hybrid co-activator interaction and co-repressor release assays were utilized to elucidate the molecular mechanism of PXR activation.

KEY RESULTS All atorvastatin metabolites induced the assembly of PXR and activated CYP3A4 promoter activity. Ligand binding to CAR could not be proven. In primary human hepatocytes, the para-hydroxy metabolite markedly reduced or abolished induction of cytochrome P450 and transporter genes. While significant differences in co-activator recruitment were not observed, para-hydroxy atorvastatin demonstrated only 50% release of co-repressors.

CONCLUSIONS AND IMPLICATIONS Atorvastatin metabolites are ligands of PXR but not of CAR. Atorvastatin metabolites demonstrate differential induction of PXR target genes, which results from impaired release of co-repressors. Consequently, the properties of drug metabolites have to be taken into account when analysing PXR-dependent induction of drug metabolism and transport. The drug interaction potential of the active metabolite, para-hydroxy atorvastatin, might be lower than that of the parent compound.
Prionobelum Verhoeff 1924
Creators: name: Donworth, Patrick
name: Wesener, Thomas
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Diplopoda
Sphaerotheriida
Zephroniidae
Prionobelum

description: Genus Prionobelum Verhoeff, 1924
Prionobelum Verhoeff, 1924: 58 (first description); Attems 1926: 120 (list); Attems 1935: 131 (new species); Attems 1936: 153 (list); Attems 1943: 61 (list); Attems 1953: 155 (list); Jeekel 1971: 27 (list); Jeekel 1974: 46 (classification); Hoffman 1976: 119 (classification); Hoffman 1980: 63 (list); Jeekel 2001: 16 (list); Mauriès 2001: 131 (classification); Wesener & VandenSpiegel 2009: 551 (list); Enghoff et al. 2015: 374 (list).
Synonyms:
Chinosphaera Attems, 1935: 130, synonymized by Mauriès 2001: 139. Attems 1936: 153; Attems 1943: 61; Jeekel 1971: 24; Jeekel 1974: 46; Hoffman 1976: 119; Hoffman 1980: 63; Jeekel 2001: 13; Mauriès 2001: 132.
Type-species: Chinosphaera maculosa Attems, 1935.
Remarks: For a recent revision see the literature (Mauriès 2001). The genus is still ill-defined, especially vis-á-vis the genera Cryxus Leach, 1814 (see Golovatch et al. 2012) and Tigridosphaera Jeekel, 2000.
Type species: Prionobelum durum Verhoeff, 1924, from Vietnam
Included species:
Prionobelum durum Verhoeff, 1924 (Vietnam)
Prionobelum hainani (Gressitt, 1941) (China: Hainan)
Prionobelum joliveti Mauriès, 2001 (China: Hainan)
Prionobelum leve (Attems, 1938) (Vietnam)
Prionobelum maculosum (Attems, 1935) (China: Fukien)
Prionobelum majorinum (Zhang & Li, 1982) (China: Hainan)
Prionobelum multidentata (Wang & Zhang, 1993) (China: Fujian)
Prionobelum inthanonense n. sp. (Thailand)
Prionobelum naevium n. sp. (Thailand)
Distribution: China, Vietnam, Thailand
description: Published as part of Donworth, Patrick & Wesener, Thomas, 2024, The first record of the giant pill-millipede genus Prionobelum Verhoeff, 1924 from Thailand, with the integrative description of two species (Diplopoda, Sphaerotheriida, Zephroniidae), pp. 545-562 in Zootaxa 5419 (4) on page 550, DOI: 10.11646/zootaxa.5419.4.4, http://zenodo.org/record/10798741
title: Sorting Network based Full Adders for QDI Circuits
Creators: name: Huemer, Florian Ferdinand
name: Steininger, Andreas
Publisher: name: TU Wien
Year: 2020
Subjects: asynchronous circuits
QDI
full adders
sorting networks

description: In this paper we focus on the efficient design of ripple-carry adders (RCAs) in quasi delay-insensitive (QDI) logic. We review approaches from the literature that are suitable for implementation in modern CMOS technology and identify their weaknesses. Based on these insights we propose novel full adder designs that are built around binary sorting networks. In order to maintain the timing robustness of QDI logic, a thorough management of gate orphans is necessary. Our analysis gives evidence that the proposed circuits are more area efficient than existing approaches, while still maintaining a comparable performance in terms of average delay.
Automated theorem proving for dependent typed theories via a translation to higher-order logic
Creators: name: Rothgang, Colin
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Higher-order logic
subject: 000 Informatik, Informationswissenschaft, allgemeine Werke::000 Informatik, Wissen, Systeme::000 Informatik, Informationswissenschaft, allgemeine Werke

description: Higher-order logic (HOL) offers a simple syntax and semantics for representing and reasoning about typed mathematical concepts. There are many state-of-the-art automated theorem provers for HOL. But the type system of HOL lacks advanced features where types may depend on terms. This is useful as many mathematical notions are inherently dependent typed. Dependent type theory offers such a rich type system but has rather substantial conceptual differences to HOL and isn’t supported as well by automated theorem provers. We introduce a dependently typed extension DHOLP of HOL that supports dependent types while retaining the style and conceptual framework of HOL. Moreover, we describe one translation from DHOLP and a second one from one of its fragments to HOL and prove the soundness and completeness of the translations. We implement both translations within the MMT system—a system for formalizing mathematics—where they are combined with a HOL prover into an automated theorem prover for DHOLP. Finally, we formalize basic set theory notions in DHOLP and outline how such a formalization can be combined with a recent translation of the language of the Mizar proof assistant to MMT to obtain an automated theorem prover for problems in the language of the Mizar proof assistant.
he RaMu Protocol: A Framework for Logical Cohesion and Non-Linear Transformation
Creators: name: Sambey, Stanley Everett
Publisher: name: Zenodo
Year: 2025

description: The RaMu Protocol represents a groundbreaking framework for understanding and navigatingreality through the principles of logical cohesion, non-linear application of data, and purelogic. Grounded in the unchallengeable axioms of uwit (ultimate wisdom, insight, or truth), theprotocol functions as a self-referential system that disrupts irrationality and immorality, acting asa virus of reason in chaotic systems. This paper explores the theoretical foundations of theRaMu Protocol, its applications, and its implications for transforming individual and collectiveconsciousness.
The RaMu Protocol: A Framework for Logical Cohesion and Non-Linear Transformation
Creators: name: Sambey, Stanley Everett
Publisher: name: Zenodo
Year: 2025

description: The RaMu Protocol represents a groundbreaking framework for understand-ing and navigating reality through the principles of logical cohesion, non-linearapplication of data, and pure logic. Grounded in the unchallengeable axiomsof uwit (ultimate wisdom, insight, or truth), the protocol functions as a self-referential system that disrupts irrationality and immorality, acting as a virusof reason in chaotic systems.
Creation of de novo cryptic splicing for ALS and FTD precision medicine
Creators: name: Wilkins, Oscar G
name: Chien, Max ZYJ
name: Wlaschin, Josette J
name: Barattucci, Simone
name: Harley, Peter
name: Mattedi, Francesca
name: Mehta, Puja R
name: Pisliakova, Maria
name: Ryadnov, Eugeni
name: Keuss, Matthew J
name: Thompson, David
name: Digby, Holly
name: Knez, Lea
name: Simkin, Rebecca L
name: Diaz, Juan Antinao
name: Zanovello, Matteo
name: Brown, Anna-Leigh
name: Darbey, Annalucia
name: Karda, Rajvinder
name: MC Fisher, Elizabeth
name: Cunningham, Thomas J
name: Le Pichon, Claire E
name: Ule, Jernej
name: Fratta, Pietro
Publisher: name: The Francis Crick Institute
Year: 2024
Subjects: classificationCode: Stem Cells
subject: Stem Cells
classificationCode: Ecology,Evolution & Ethology
subject: Ecology,Evolution & Ethology
classificationCode: Gene Expression
subject: Gene Expression
classificationCode: Genetics & Genomics
subject: Genetics & Genomics
classificationCode: Computational & Systems Biology
subject: Computational & Systems Biology
classificationCode: Neurosciences
subject: Neurosciences
subject: FOS: Clinical medicine
classificationCode: Biochemistry & Proteomics
subject: Biochemistry & Proteomics

description: Loss of function of the RNA-binding protein TDP-43 (TDP-LOF) is a hallmark of amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders. Here we describe TDP-REG, which exploits the specificity of cryptic splicing induced by TDP-LOF to drive protein expression when and where the disease process occurs. The SpliceNouveau algorithm combines deep learning with rational design to generate customizable cryptic splicing events within protein-coding sequences. We demonstrate that expression of TDP-REG reporters is tightly coupled to TDP-LOF in vitro and in vivo. TDP-REG enables genomic prime editing to ablate the UNC13A cryptic donor splice site specifically upon TDP-LOF. Finally, we design TDP-REG vectors encoding a TDP-43/Raver1 fusion protein that rescues key pathological cryptic splicing events, paving the way for the development of precision therapies for TDP43-related disorders.
Immediate vs. delayed insertion of intrauterine contraception after second trimester abortion: study protocol for a randomized controlled trial
Creators: name: Norman, Wendy V
name: Kaczorowski, Janusz
name: Soon, Judith A
name: Brant, Rollin
name: Bryan, Stirling
name: Trouton, Konia J
name: Dicus, Lyda
Publisher: name: BioMed Central
Year: 2016

description: Background: We describe the rationale and protocol for a randomized controlled trial (RCT) to assess whether intrauterine contraception placed immediately after a second trimester abortion will result in fewer pregnancies than current recommended practice of intended placement at 4 weeks post-abortion. Decision analysis suggests the novel strategy could substantially reduce subsequent unintended pregnancies and abortions. This paper highlights considerations of design, implementation and evaluation of a trial expected to provide rigorous evidence for appropriate insertion timing and health economics of intrauterine contraception after second trimester abortion. Methods/Design: Consenting women choosing to use intrauterine contraception after abortion for a pregnancy of 12 to 24 weeks will be randomized to insertion timing groups either immediately (experimental intervention) or four weeks (recommended care) post abortion. Primary outcome measure is pregnancy rate at one year. Secondary outcomes include: cumulative pregnancy rates over five year follow-up period, comprehensive health economic analyses comparing immediate and delayed insertion groups, and device retention rates, complication rates (infection, expulsion) and, contraceptive method satisfaction. Web-based Contraception Satisfaction Questionnaires, clinical records and British Columbia linked health databases will be used to assess primary and secondary outcomes. Enrolment at all clinics in the province performing second trimester abortions began in May 2010 and is expected to complete in late 2011. Data on one year outcomes will be available for analysis in 2014. Discussion: The RCT design combined with access to clinical records at all provincial abortion clinics, and to information in provincial single-payer linked administrative health databases, birth registry and hospital records, offers a unique opportunity to evaluate such an approach by determining pregnancy rate at one through five years among enrolled women. We highlight considerations of design, implementation and evaluation of a trial expected to provide rigorous evidence for appropriate insertion timing and health economics of intrauterine contraception after second trimester abortion. Trial registration: Current Controlled Trials ISRCTN19506752
Developing English and Information Technological Potential for Ornamental Fish Famers in Nakhon Pathom Province for Getting Ready to the Asean Economic Community (AEC)
Creators: name: Sompon Sukcharoenpong
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University.
Year: 2014
Subjects: Developing
Potential
Ornamental Fish
Famers
Asean Economic Community

description: Journal of Management Science Nakhon Pathom Rajabhat University, 1, 2, 56-69
Mycorrhization enhances plant growth and stabilizes biomass allocation under drought
Creators: name: Tang, Bo
name: Man, Jing
name: Romero, Ferran
name: Bergmann, Joana
name: Lehmann, Anika
name: Rillig, Matthias C.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: arbuscular mycorrhizal (AM) fungi
subject: biomass allocation
subject: drought
subject: global change
subject: meta-analysis
subject: plant biomass
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Plants and their symbionts, such as arbuscular mycorrhizal (AM) fungi, are increasingly subjected to various environmental stressors due to climate change, including drought. As a response to drought, plants generally allocate more biomass to roots over shoots, thereby facilitating water uptake. However, whether this biomass allocation shift is modulated by AM fungi remains unknown. Based on 5691 paired observations from 154 plant species, we conducted a meta-analysis to evaluate how AM fungi modulate the responses of plant growth and biomass allocation (e.g., root-to-shoot ratio, R/S) to drought. We found that AM fungi attenuate the negative impact of drought on plant growth, including biomass production, photosynthetic performance and resource (e.g. nutrient and water) uptake. Accordingly, drought significantly increased R/S in non-inoculated plants, but not in plants symbiotic with established AM fungal symbioses. These results suggest that AM fungi promote plant growth and stabilize their R/S through facilitating nutrient and water uptake in plants under drought. Our findings highlight the crucial role of AM fungi in enhancing plant resilience to drought by optimizing resource allocation. This knowledge opens avenues for sustainable agricultural practices that leverage symbiotic relationships for climate adaptation.
Relationship between organizational commitment and citizenship behaviors of personnel in subdistrict administrative organizations in Samphran District, Nakhon Pathom Province.
Creators: name: Panatda Kirin
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University.
Year: 2014
Subjects: organizational commitment and citizenship behavior
ubdistrict administrative organization
Nakhon Pathom Province

description: Journal of Management Science Nakhon Pathom Rajabhat University, 1, 2, 70-85
Leadership and Organizational Culture Favorable to the Success of Modern Organization Development : A Case Study of Metropolitan Operating Line of Thai Postage Company
Creators: name: Phapassorn Woraphatthirakun
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University
Year: 2015
Subjects: leadership
organizational culture
modern organization development
metropolitan operating line

description: Journal of Management Science Nakhon Pathom Rajabhat University, 2, 2, 1-12