cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A multi-patient analysis of the center of rotation trajectories using finite element models of the human mandible
Creators: name: Gholamalizadeh, Torkan
name: Darkner, Sune
name: Søndergaard, Peter Lempel
name: Erleben, Kenny
Publisher: name: arXiv
Year: 2022
Subjects: subject: Medical Physics (physics.med-ph)
subject: Computational Engineering, Finance, and Science (cs.CE)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Studying different types of tooth movements can help us to better understand the force systems used for tooth position correction in orthodontic treatments. This study considers a more realistic force system in tooth movement modeling across different patients and investigates the effect of the couple force direction on the position of the center of rotation (CRot). The finite-element (FE) models of human mandibles from three patients are used to investigate the position of the CRots for different patients' teeth in 3D space. The CRot is considered a single point in a 3D coordinate system and is obtained by choosing the closest point on the axis of rotation to the center of resistance (CRes). A force system, consisting of a constant load and a couple (pair of forces), is applied to each tooth, and the corresponding CRot trajectories are examined across different patients. To perform a consistent inter-patient analysis, different patients' teeth are registered to the corresponding reference teeth using an affine transformation. The selected directions and applied points of force on the reference teeth are then transformed into the registered teeth domains. The effect of the direction of the couple on the location of the CRot is also studied by rotating the couples about the three principal axes of a patient's premolar. Our results indicate that similar patterns can be obtained for the CRot positions of different patients and teeth if the same load conditions are used. Moreover, equally rotating the direction of the couple about the three principal axes results in different patterns for the CRot positions, especially in labiolingual direction. The CRot trajectories follow similar patterns in the corresponding teeth, but any changes in the direction of the force and couple cause misalignment of the CRot trajectories, seen as rotations about the long axis of the tooth.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.01.1956, erstellt von Eugène Pourbaix, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.01.1956, erstellt von M. am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Auf dem Formular ist vermerkt: Slovenska akademia vied, Slowakische Akademie der Wissenschaften. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Sonnenfleckenzeichnung Nr. 19284.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.04.1956, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 19266.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.03.1956, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.01.1956, erstellt von Eugène Pourbaix, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Right Honble. Robert Earl Nugent.
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1760
Subjects: Nugent, RobertdpcAbgebildet

description: Radierung und Kupferstich. Blatt beschnitten und mit Textfeld versehen. Dargestellt ist der Politiker und Schriftsteller Robert Craggs-Nugent, 1st Earl Nugent (1709-1788).
Sonnenfleckenzeichnung Nr. 19248.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.03.1956, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.04.1956, erstellt von Wolfgang Gleissberg an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
Sonnenfleckenzeichnung Nr. 19242.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 01.03.1956, erstellt von Adolf Lemans
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
ReLyMe: Improving Lyric-to-Melody Generation by Incorporating Lyric-Melody Relationships
Creators: name: Zhang, Chen
name: Chang, Luchin
name: Wu, Songruoyao
name: Tan, Xu
name: Qin, Tao
name: Liu, Tie-Yan
name: Zhang, Kejun
Publisher: name: arXiv
Year: 2022
Subjects: subject: Sound (cs.SD)
subject: Multimedia (cs.MM)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Lyric-to-melody generation, which generates melody according to given lyrics, is one of the most important automatic music composition tasks. With the rapid development of deep learning, previous works address this task with end-to-end neural network models. However, deep learning models cannot well capture the strict but subtle relationships between lyrics and melodies, which compromises the harmony between lyrics and generated melodies. In this paper, we propose ReLyMe, a method that incorporates Relationships between Lyrics and Melodies from music theory to ensure the harmony between lyrics and melodies. Specifically, we first introduce several principles that lyrics and melodies should follow in terms of tone, rhythm, and structure relationships. These principles are then integrated into neural network lyric-to-melody models by adding corresponding constraints during the decoding process to improve the harmony between lyrics and melodies. We use a series of objective and subjective metrics to evaluate the generated melodies. Experiments on both English and Chinese song datasets show the effectiveness of ReLyMe, demonstrating the superiority of incorporating lyric-melody relationships from the music domain into neural lyric-to-melody generation.
description: Accepted by ACMMM 2022, oral
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.03.1956, erstellt von L. Mrkosova-Pajdusakova am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Auf dem Formular ist vermerkt: Slovenska akademia vied, Slowakische Akademie der Wissenschaften. Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Sonnenfleckenzeichnung Nr. 19234.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.02.1956, erstellt von Helmut Müller und Adolf Lemans
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.01.1956, erstellt von Eugène Pourbaix, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 01.04.1956, erstellt von Adnan Kiral an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
Investigating a predicted metallicity [Fe/H] variation in the Type II Globular Cluster NGC 362
Creators: name: Vargas, C.
name: Villanova, S.
name: Geisler, D.
name: Muñoz, C.
name: Monaco, L.
name: O'Connell, J.
name: Sarajedini, Ata
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: NGC 362 is a non-common Type II Galactic globular cluster, showing a complex pseudo two-color diagram or 'chromosome map'. The clear separation of its stellar populations in the color-magnitude diagram and the distribution of the giant stars in the chromosome map strongly suggests that NGC 362 could host stars with both cluster-nominal as well as enhanced heavy-element abundances, and one of them could be iron. However, despite previous spectroscopic observations of NGC 362, no such iron variation has been detected. Our main goal is to confirm or disprove this result by searching for any internal variation of [Fe/H] which would give us insight into the formation and evolution of this interesting globular cluster. In this paper, we present the abundance analysis for a sample of 11 red giant branch members based on high-resolution and high S/N spectra obtained with the MIKE echelle spectrograph mounted at the Magellan-Clay telescope. HST and GAIA photometry and astrometry has been used to determine atmospheric parameters and membership. We obtained T$_{\text{eff}}$, log(g) and v$_{\text{t}}$ for our target stars and measured the mean iron content of the sample and its dispersion with three different methods, which lead to [Fe/H]$_1$=-1.10$\pm0.02$, [Fe/H]$_2$=-1.09$\pm0.01$ and [Fe/H]$_3$=-1.10$\pm0.01$, while the internal dispersion turned out to be $σ_{[\text{Fe/H}]_1}$=0.06$\pm0.01$, $σ_{[\text{Fe/H}]_2}$=0.03$\pm0.01$ and $σ_{[\text{Fe/H}]_3}$=0.05$\pm0.01$ respectively. The error analysis gives an internal dispersion due to observational error of 0.05 dex. Comparing the observed dispersion with the internal errors, we conclude that NGC 362 does not show any trace of an internal iron spread.
description: 11 pages, 6 figures
Sonnenfleckenzeichnung Nr. 19210.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.01.1956, erstellt von Adolf Lemans
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 19265.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.03.1956, erstellt von Helmut Müller und Adolf Lemans
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Fatigue crack growth in bearing steel under cyclic mode II + static biaxial compression
Creators: name: Zaid, Mael
name: Bonnand, Vincent
name: Doquet, Véronique
name: Chiaruttini, Vincent
name: Pacou, Didier
name: Depouhon, Pierre
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Mode II fatigue crack growth under reversed shear and static biaxial compression was investigated in two bearing steels. Many aborted branches, quasi-orthogonal to the main crack, were observed along the crack face. The compressive stress parallel to the main crack hindered the growth of these branches and favored coplanar mode II crack growth. The crack face sliding displacement profiles measured by DIC were used to derive $Δ_{\rm KII,eff}$, at the main crack tip, using elastic-plastic FE simulations with crack face friction, by an inverse method. Friction corrected crack growth kinetics were obtained for mode II crack growth in both steels.
Sonnenfleckenzeichnung Nr. 19285.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.04.1956, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
The Pharmacokinetics of Pirmenol During Short Term Oral Dosing
Creators: name: Matyunas, Nancy Jo
Publisher: name: University of Utah
Year: 2016
Subjects: Piperidines - Research
Anti-Arrhythmai Agents
Pharmacokinetics
Cardiac Electrophysiology - Treatment
Hemodynamics

description: The clinical use of currently available antiarrhythmic agents has been plagued with numerous problems. Many arrhythmias, particularly recurrent ventricular tachycardia are frequently not controlled with these drugs. If these drugs are efficacious, chronic dosing often produces adverse effects which are serious or intolerable to the patient. Dosage schedules are often inconvenient due to the limited duration of effect. Moreover, oral dosage forms are not available for some antiarrhythmic agents.  Pirmenol is an investigational antiarrhythmic agent which possesses electrophysiologic actions similar to the existing Type 1 agents, quinidine, procainamide and disopyramide. The drug is structurally similar to disopyramide. Pirmenol has been demonstrated to suppress premature ventricular contractions in animals and humans. Reported side effects have been minimal. In a post-infarction coronary ligated Harris dog model, Pirmenol administered intravenously, intramuscularly, or orally resulted in prompt conversion of ventricular arrhythmias to normal sinus rhythm. It was also effective in reversing ouabain and epinpherne-induced ventricular arrhythmias and aconitine-induced atrial arrhythmias. The drug did not interfer with electroconversion to normal sinus rhythm and ventricular fibrillation threshold was elevated. Effects on cardiac conduction were minimal at therapeutic doses. Some transient myocardial depression manifested as an increase in heart rate and decrease in contractility was noted and felt to be secondary to rapid infusion of the drug. The cardiac output was maintained.
The Roles of Cyclooxygenase-2 and Protein Kinase C Delta in Mutant Epidemal Growth Factor Receptor Non-Small Cell Lung Cancer
Creators: name: Kim, Mun kyoung
Publisher: name: University of Utah
Year: 2016
Subjects: Lungs - Cancer
Lungs - Cancer - Physiological aspects
Lungs - Cancer - Genetic aspects
Epidermal growth factor
Celecoxib
COX-2
EGFR
IL-6 Lung Cancer
PKCd

description: Lung cancer causes more than 1 million deaths in every year worldwide, and is the leading cause of cancer-related death in the United States. Targeting epidermal growth factor receptor (EGFR) in non-small cell lung cancer (NSCLC) harboring activating mutations in EGFR is an effective treatment but is eventually limited by drug-resistance. This has led to a pressing need to identify alternative treatments or additional targets for resistant tumors. I found abundant activation of cyclooxygenase-2 (COX-2) signal in mutant EGFR NSCLC, suggesting that it might play tumorigenic roles in these tumors. Targeting COX-2 in mutant EGFR lung cancer cells and transgenic mouse models of mutant EGFR lung cancer reduced tumor cell growth, and was more effective in combination with EGFR inhibition. I found that COX-2 signaling regulates interleukin-6 (IL-6) transcription leading to signal transducer and activator of transcription 3 (STAT3) activation. These findings demonstrate that COX-2 modulates the IL-6/STAT3 signaling axis in mutant EGFR NSCLC and targeting COX-2 in combination with EGFR inhibition could be an effective strategy to treat mutant EGFR NSCLC. Since COX-2 inhibition is a promising chemopreventive agent in other cancers; therefore, I next hypothesized that targeting COX-2 might be a viable strategy to prevent tumor formation. Using transgenic mouse models, I found that targeting COX-2 prior to tumor development delayed tumor formation, which suggests that COX-2 inhibition could be a potential strategy to delay or prevent development of mutant EGFR NSCLC. iv In further efforts to identify other targets in mutant EGFR lung cancer, I found evidence of abundant activation of protein kinase C δ (PKCδ). This kinase normally functions as a tumor-suppressor, but it also is considered as a tumor-promoter in some contexts. I found reduced growth of mutant EGFR human lung cancer cells under PKCδ depletion. I also discovered that PKCδ promotes IL-6/STAT3 signal in mutant EGFR NSCLC, suggesting that PKCδ is a tumor-promoter in mutant EGFR NSCLC. Collectively, my data indicate that PKCδ is a potential target to treat mutant EGFR NSCLC. In this dissertation, I identified COX-2 and PKCδ as novel targets for treating mutant EGFR NSCLC and defined their oncogenic roles in mutant EGFR NSCLC by regulating the critical oncogenic signal, IL-6/STAT3.
Piperacillin Pharmacokinetics in Patients with Chronic Renal Failure
Creators: name: Thompson, Marietta Ione Bunn
Publisher: name: University of Utah
Year: 2016
Subjects: Piperacillin - Research
Clinical trials, Phase III as topic
Kidney Failure, Chronic - Treatment
Renal Elimination
Osmolar Concentration

description: Piperacillin sodium is currently and ivestigational drug undergoing Phas III clinical trials. The drug is a penicillin derivative. Piperacillin has been shown to be effective in the treatment of serious infections. In vitro and in vivo studies demonstrate that Piperacillin has a broad spectrum of activity. It is effective against most gram-positive and gram-negative organisms including anaerobes. Its gram-negative spectrum includes Escherichia coli, Enerobactere cloacae, Proteus mirabilis (indole-negative Proteus), Proteus vulgaris (indole-positive Proteus), Serratia marcescens and Klebsiella pneumoniae. It is four to eight-fold more active than carbenicillin in inhibiting Pseudomonas aeruginosa and folds-fold more active against Bacteriodes fragilis.  The pharmacokinetics of Piperacillin have been studied in patients with normal renal function and dosage recommendations are fairly well established for this group of patients. Very little work has been done on the pharmacokinetics of this drug in patients with end-stage renal failure. Due to the increased risk of infection in this population, Piperacillin may be an important drug in the treatment of infections in this group.
The Prevalence of Asymtomatic Bacteriuria in Women with Pregnancy-Induced Hypertension
Creators: name: Foster, Dianne Elizabeth
Publisher: name: University of Utah
Year: 2016
Subjects: Symptomatic urinary infection - Research
Hypertension, Pregnancy-Induced

description: In 1960, Kass first demonstrated a strong relationship between untreated asymptomatic bacteriuria and the development of pyelonephritis during pregnancy results in an increased risk of fetal morbidity and mortality. Fortunately, with adequate antibiotic treatment, it is possible to decrease both the incidence of this infection process in pregnant women and accompanying fetal risks. Symptomatic urinary tract infection may also have other adverse effects on pregnancy, including preterm labor, fetal growth retardation, fetal loss, and maternal anemia. While the relationship between symptomatic urinary infectious disease and the above pregnancy outcomes is fairly well-established, a relationship between these effects and asymptomatic bacteriuria has not yet been clearly proven and is still being debated in the medical literature.  The drawbacks of the studies performed thus far regarding asymptomatic bacteriuria and PIH have made them difficult to interpret and apply in clinical practice. Debate in this area continues due to contradictory research findings by several different investigators. Since a satisfactory cause-and-effect relationship has not been established by the reports, a need exists for a better-defined, well-controlled study to examine whether and association exists between these two disorders. The objectives of this study, therefore, was to determine if a difference exists in the prevalence of PIH between women with asymptomatic bacteriuria and women without asymptomatic bacteriuria by improving study design where possible and using appropriate statistical analysis of data.
Letter from Jonathan Abbatt to Mary Dilworth (later Abbatt), February 15, 1853
Creators: name: Abbatt, Jonathan, 1829-1905
Publisher: name: University of Victoria Libraries
Year: 2022
Subjects: subject: Quakers--Family relationships
valueUri: http://id.worldcat.org/fast/1084922
subject: Quakers
valueUri: http://id.worldcat.org/fast/1084913
subject: Man-woman relationships
valueUri: http://id.worldcat.org/fast/1007080
subject: Families
valueUri: http://id.worldcat.org/fast/1728849
subject: Courtship
valueUri: http://id.worldcat.org/fast/881873
subject: Faith
valueUri: http://id.worldcat.org/fast/1198492
subject: Marriage
valueUri: http://id.worldcat.org/fast/1010443
subject: Man-woman relationships--Religious aspects
valueUri: http://id.worldcat.org/fast/1007090
subject: Interpersonal relations
valueUri: http://id.worldcat.org/fast/977397

description: This letter is part of a series of courtship correspondence between Jonathan Abbatt and Mary Dilworth (later Abbatt). The Abbatt family was a Quaker family who lived in the towns and villages of Preston, Ribchester, and Garstang in Lancashire, England. The letters chronicle the courtship, discussions of faith, local events, shared sentiments, etc. Mary sometimes addressed as Polly in the letters. Please note that the months on the letters’ dates were added as numerical values rather than the month's name (e.g. 2 Mo = February). Jonathan mentions again that he's interested in her, but doesn't think it's a good idea to say more until he gets her parents' consent. He discusses which day would be a good time to visit her and talk to her parents. Since he was just in Calder, he doesn't want to travel there again so soon after as that could raise suspicion, so he's looking at Good Friday as the next opportunity to travel over.
Sonnenfleckenzeichnung Nr. 19212.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.01.1956, erstellt von Adolf Lemans
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 19238.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.02.1956, erstellt von Adolf Lemans
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.02.1956, erstellt von L. Mrkosova-Pajdusakova am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Auf dem Formular ist vermerkt: Slovenska akademia vied, Slowakische Akademie der Wissenschaften. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Datanator: an integrated database of molecular data for quantitatively understanding cellular behavior
Creators: name: Roth, Yosef
name: Lian, Zhouyang
name: Pochiraju, Saahith
name: Shaikh, Bilal
name: Karr, Jonathan R
Publisher: name: Zenodo
Year: 2020
Subjects: molecular biology
systems biology
computational biology
bioinformatics
data integration
database
modeling
simulation

description: Datanator (https://datanator.info) is an integrated database of genomic and biochemical data designed to help investigators find data about specific molecules and reactions in specific organisms and specific environments for meta-analyses and mechanistic models. For example, Datanator includes metabolite concentrations, RNA modifications and half-lives, protein abundances and modifications, and reaction kinetics integrated from several databases and numerous publications. We recommend that researchers use the Datanator website and REST API to extracting clouds of data about specific molecules and reactions in specific organisms and specific environments, as well as data about similar molecules and reactions in taxonomically similar organisms. This archive is a copy of the entire Datanator database. This archive is suitable for researchers who wish to analyze the entire database. The archive is a snapshot of the Datanator MongoDB database. Instructions for restoring the snapshot are available at https://datanator.info/help/.
description: Funding: - NIH grant P41EB023912 - NIH grant R35GM119771
Comparison of Manual and Automated Cell Counts in the Diagnosis of Pediatric Appendicitis
Creators: name: Regginello, Tara Jewel
Publisher: name: University of Utah
Year: 2016
Subjects: Abdominal Pain - Appendiciits
Complete blood count
Immature Granulocyte
Pediatric
White Blood Cell Differential

description: Children with appendicitis present with nonspecific symptoms such as abdominal pain, fever, and vomiting. Clinicians utilize clinical findings, and laboratory and imaging tests to determine the likelihood of appendicitis. A complete blood count (CBC) with manual differential is ordered to determine if the patient has an increased number of white blood cells (WBCs) or immature WBCs present in the peripheral blood (known as a left shift). Leukocytosis (WBC count >10,000/uL), left shifted differential, elevated band count, and neutrophilia >75% are used to risk-stratify patients with suspected appendicitis. Immature granulocyte percentage (IG%) is an alternative measurement of left shift. The IG% can be obtained from an automated differential, which is faster, more reproducible, and less subject to sampling error. A cohort definition was used to compile data including patients who presented with a chief complaint of abdominal pain, and patients who received an ultrasound of the appendix in the Primary Children's Hospital emergency department (ED). Data collected included patient age, WBC count and differential, IG%, and pathology report. A diagnosis of acute appendicitis was determined by the pathology reports. The sensitivity, specificity, and area under receiver operating characteristic curves (AUC) were determined for total WBC count (>10,000/μL), band count, IG%, and neutrophil percentage (>75%). iv The total WBC count (>10,000/μL) showed the best predictive value with a sensitivity of 85.3%, specificity of 63.4%, and AUC of 80.1%. A neutrophil percentage >75% was also predictive of appendicitis with a sensitivity of 70.5%, specificity of 66.6%, and AUC of 73.4%. Band count showed no predictive value with an AUC of 57.7%. IG% was slightly more useful with a sensitivity of 68.5, specificity of 59.7%, and AUC of 66.7%. The parameters obtained from a CBC with automated differential count: WBC count, neutrophil percentage, and IG%; were each more successful in correctly identifying pediatric patients with appendicitis than band count, which was not a reliable indicator and showed no added benefit in diagnosis. Eliminating the band count, and hence the need for a manual differential, could improve turn-around-time for patients presenting with abdominal pain without reducing the utility of the CBC.
Development of the Theory of Wisdom in Action for Clinical Nursing
Creators: name: Matney, Susan A.
Publisher: name: University of Utah
Year: 2016

description: As nurses, we seek to gain nursing wisdom and apply it in our daily practice, yet the process of practicing with wisdom has not been well explained for nursing. The purpose of this dissertation was to develop a theory of wisdom in action (WIA) for clinical nursing, beginning with a formal concept analysis. In Phase 1 (Aim 1), a preliminary theory was developed deductively using derivation and synthesis, based on theories and models from psychology, education, and nursing. Pertinent concepts were identified and nursing-specific definitions created. The theory included four dimensions: person-related factors, environment-related factors, knowledge, and wisdom. Separately, a constructivist grounded theory approach inductively captured the experience of wisdom in nursing practice (Aim 2), based on wisdom narratives from 30 emergency department nurses. The resulting grounded theory focused on two processes, technical and affective, juxtaposed on a foundation of expertise. New findings were the importance of affective characteristics such as emotional intelligence and confidence. Finally, the theories were synthesized into the Theory of Wisdom in Action for Clinical Nursing. The theory describes two antecedent dimensions, person-related and setting-related factors, and two types of wisdom processes. General wisdom processes apply to patient care and describe the actions nurses take during a stressful or uncertain event. Personal wisdom develops afterwards, as a feedback loop with reflection, discovery of meaning, and learning, followed by increased knowledge and confidence. Wisdom is critical for all areas of nursing practice. The Theory of Wisdom in Action for Clinical Nursing provides a working framework for translating wisdom in clinical nursing practice into theoretical and practical terms, depicting both the science and the art of nursing. This novel theory displays how nurses practice with wisdom, and reveals that wisdom in action requires clinical skills, experience, knowledge, and affective proficiency.
AGBoost: Attention-based Modification of Gradient Boosting Machine
Creators: name: Konstantinov, Andrei
name: Utkin, Lev
name: Kirpichenko, Stanislav
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: A new attention-based model for the gradient boosting machine (GBM) called AGBoost (the attention-based gradient boosting) is proposed for solving regression problems. The main idea behind the proposed AGBoost model is to assign attention weights with trainable parameters to iterations of GBM under condition that decision trees are base learners in GBM. Attention weights are determined by applying properties of decision trees and by using the Huber's contamination model which provides an interesting linear dependence between trainable parameters of the attention and the attention weights. This peculiarity allows us to train the attention weights by solving the standard quadratic optimization problem with linear constraints. The attention weights also depend on the discount factor as a tuning parameter, which determines how much the impact of the weight is decreased with the number of iterations. Numerical experiments performed for two types of base learners, original decision trees and extremely randomized trees with various regression datasets illustrate the proposed model.
description: Proceedings of the 31st Conference of Open Innovations Association (FRUCT), 2022
Jun Signaling During Drosophila Development
Creators: name: Jud, Molly Christine
Publisher: name: University of Utah
Year: 2016

description: Jun N-terminal kinase (JNK) signaling is a key modulator of development and disease in all multicellular organisms. One process in which the consequences of both gain and loss of JNK signaling can be monitored is embryonic dorsal closure (DC) in the fruit fly, Drosophila melanogaster. DC occurs midway through embryogenesis; it is the process by which the lateral epidermis expands bilaterally to meet and fuse at the dorsal midline, thereby encasing the entire embryo in epidermis. JNK signaling in leading edge (LE) cells (the dorsal-most row of epidermis) initiates closure. My studies of a novel but conserved JNK signaling antagonist, Raw, have provided several unique insights into: 1) Jun function as a component of the AP-1 transcription factor, and 2) the role of the epidermis as a signaling template mediating development of the epidermis and adjacent tissues. My graduate work has built upon the demonstration that raw is required to prevent promiscuous JNK signaling in the embryonic epidermis just prior to DC. I have shown that raw is necessary for proper accumulation of Jun in LE cells required to define the LE, which functions as a signaling center required for epidermal closure as well as for underlying heart development. I have gone on to show that Jun accumulates at previously unrecognized sites in the embryonic epidermis, including tracheal pits and solitary epidermal cells lying directly above the peripheral nervous system (PNS). Jun activity is required for tracheal and nervous system defects observed in mutants of two JNK signaling antagonists, raw and rib, and indicates that cell signals within and to an adjacent tissue are integral to proper development. I have found that the epidermis iv plays an instructive role during development, and results from my work have led to insights into how JNK signaling centers in the epidermis coordinate morphological processes. As Raw is a novel but conserved JNK signaling antagonist, I have built and tested models of its molecular mechanism of action as well. Bolstering conclusions of previous studies of mammalian c-Jun in cell culture, my data indicate that N-terminal phosphorylation is not an on/off switch, but rather it increases Jun stability for its activity as a component of the AP-1 transcription factor. raw mutants exhibit both high levels of Jun protein and an accumulation of phosphorylated Jun (P-Jun), and my data point to a role for Raw in effecting the Jun:P-Jun ratio via mediation of Jun degradation. In deciphering the mechanism of Raw function, we are gaining significant new insights into previously unrecognized mechanisms of JNK signaling regulation. Understanding these mechanisms will be important for dissecting the etiology of developmental abnormalities and diseases, such as cancer, which hinge on the Goldilocks effect, having just the right amount of signaling at just the right time.
Sonnenfleckenzeichnung Nr. 19262.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.03.1956, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Fluvial-lacustrine sequence stratigraphy, provenance, ichnology, and sandstone reservoir modeling of the tertiary uinta and duchesne river formation, northern uinta basin, utah
Creators: name: Sato, Takashi
Publisher: name: University of Utah
Year: 2016
Subjects: Fluvial
Lacustrine
Provenance
Reservoir
Trace fossil
Uinta Basin

description: The Tertiary Uinta and Duchesne River Formations exhibit spectacular outcrop exposures in the Uinta Basin, northeastern Utah. This paper documents four different geological topics/subjects resulting from field and laboratory studies: 1) fluvial-lacustrine sequence stratigraphy, 2) source-to-sink fluvial system, 3) ichnology and paleoenvironment implications, and 4) sandstone reservoir models and characterization.  Chapter 1 highlights a sequence stratigraphic framework and basin-scale facies architecture of the Duchesne River Formation. An upward-fining sequence of the lower three members was heavily influenced by uplift in the Uinta Mountains. Its internal fluvial-lacustrine deposits show marked contrasts between the western and eastern part of the basin due to irregular allogenic controls of tectonic subsidence and water discharge (climate and source terrain input controls).  Chapter 2 highlights a source-to-sink fluvial system of the basal member of the Duchesne River Formation, which preserves a high net-sand-to-gross-thickness ratio (NTG) system in the western sink (basin) and a low NTG system in the eastern sink. Petrographic data and drainage patterns indicate a high discharge from multiple source terrains with a long sediment transport along the E-W basin axis in the western part of the basin. These factors were important for development of large-volume and high-quality (porous) fluvial sandstone reservoirs in the sink.   Chapter 3 focuses on distinct trace fossil assemblages within the fluvial-lacustrine sequence of the uppermost Uinta and the overlying Duchesne River Formations. The study demonstrates the important relationships of depositional facies and trace fossils: 1) lacustrine deposits with the dominant horizontal grazing trace fossil assemblage, 2) fluvial deposits with  the dominant insect trace fossil assemblage, and 3) transitional (wetland) deposits with   intermediate trace fossil assemblage.   Chapter 4 emphasizes the outcrop-based geological/reservoir modeling of fluvial and lacustrine deposits of the Uinta and Duchesne River Formations. The study provides statistical inputs of fluvial channel geometry for reservoir modeling applications, and demonstrates which stochastic modeling techniques best represent observed depositional patterns derived from outcrop data. The Uinta and Duchesne River Formations exhibit the important aspects of coarse-grained deposits in the late-stage lacustrine basin fill.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.03.1956, erstellt von Edibe Balli-Tüzemen an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
Sonnenfleckenzeichnung Nr. 19283.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.04.1956, erstellt von Adolf Lemans
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 19267.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.03.1956, erstellt von Adolf Lemans
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.04.1956, erstellt von André Koeckelenbergh, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.03.1956, erstellt von Adnan Kiral an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
Faltings delta-invariant and semistable degeneration
Creators: name: de Jong, Robin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: We determine the asymptotic behavior of the Arakelov metric, the Arakelov-Green's function, and the Faltings delta-invariant for arbitrary one-parameter families of complex curves with semistable degeneration. The leading terms in the asymptotics are given a combinatorial interpretation in terms of S. Zhang's theory of admissible Green's functions on polarized metrized graphs.
description: 50 pages
Point-like limit of the hyperelliptic Zhang-Kawazumi invariant
Creators: name: de Jong, Robin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: The behavior near the boundary in the Deligne-Mumford compactification of many functions on the moduli space of pointed Riemann surfaces can be conveniently expressed using the notion of "point-like limit" that we adopt from the string theory literature. In this note we study a function on the moduli space of Riemann surfaces that has been introduced by N. Kawazumi and S. Zhang, independently. We show that the point-like limit of the Zhang-Kawazumi invariant in a family of hyperelliptic Riemann surfaces in the direction of any hyperelliptic stable curve exists, and is given by evaluating a combinatorial analogue of the Zhang-Kawazumi invariant, also introduced by Zhang, on the dual graph of that stable curve.
description: 14 pages
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.03.1956, erstellt von Wolfgang Gleissberg an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1956

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)