cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: 02_0426
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Functional gains in energy and cell metabolism after TSPO gene insertion
Creators: name: Liu, Guo-Jun
name: Middleton, Ryan J.
name: Kam, Winnie Wai-Ying
name: Chin, David Y.
name: Hatty, Claire R.
name: Chan, Ronald H. Y.
name: Banati, Richard B.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Developmental Biology
subject: Cancer

description: Recent loss-of-function studies in tissue-specific as well as global Tspo (Translocator Protein 18 kDa) knockout mice have not confirmed its long assumed indispensability for the translocation of cholesterol across the mitochondrial inter-membrane space, a rate-limiting step in steroid biosynthesis. Instead, recent studies in global Tspo knockout mice indicate that TSPO may play a more fundamental role in cellular bioenergetics, which may include the indirect down-stream regulation of transport or metabolic functions. To examine whether overexpression of the TSPO protein alters the cellular bioenergetic profile, Jurkat cells with low to absent endogenous expression were transfected with a TSPO construct to create a stable cell line with de novo expression of exogenous TSPO protein. Expression of TSPO was confirmed by RT-qPCR, radioligand binding with [3H]PK11195 and immunocytochemistry with a TSPO antibody. We demonstrate that TSPO gene insertion causes increased transcription of genes involved in the mitochondrial electron transport chain. Furthermore, TSPO insertion increased mitochondrial ATP production as well as cell excitability, reflected in a decrease in patch clamp recorded rectified K channel currents. These functional changes were accompanied by an increase in cell proliferation and motility, which were inhibited by PK11195, a selective ligand for TSPO. We suggest that TSPO may serve a range of functions that can be viewed as downstream regulatory effects of its primary, evolutionary conserved role in cell metabolism and energy production.
Additional file 1: of Genome-wide copy number variant analysis reveals variants associated with 10 diverse production traits in Holstein cattle
Creators: name: Zhou, Yang
name: Connor, Erin
name: Wiggans, George
name: Lu, Yongfang
name: Tempelman, Robert
name: Schroeder, Steven
name: Chen, Hong
name: Liu, George
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Figure S1. Box plot for dPTA distribution of the 2 feed intake-related phenotypes of RFI and DMI. (PDF 90 kb)
Fostering Inquiry through Pairing Children’s Literature with Historical Photographs
Creators: name: Anthony, Kenneth
name: Hopper, Peggy
Publisher: name: figshare
Year: 2017
Subjects: subject: Education
subject: 130105 Primary Education (excl. Maori)
subject: FOS: Educational sciences
subject: History

description: The National Council for the Social Studies College, Career, and Civic Life Framework (C3) was designedto link social studies with ELA Common Core State Standards. C3 is an Inquiry Framework and thegateway to the inquiry process is questioning. One method for fostering questioning skills involvespairing non-fiction narrative texts with related historical photographs. In this article, we provide anexample of one way that teachers can pair historical texts with photographs from digital archives in theLibrary of Congress. We provide an example of pairing historical photographs with a children’s book setin the Great Depression in Mississippi.
Additional file 1: of A case report of spontaneous abortion caused by Brucella melitensis biovar 3
Creators: name: Yang, Hong-Xia
name: Feng, Jun-Jun
name: Zhang, Qiu-Xiang
name: Hao, Rui-E
name: Yao, Su-Xia
name: Zhao, Rong
name: Piao, Dong-Ri
name: Cui, Bu-Yun
name: Jiang, Hai
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Multilingual abstracts in the five official working languages of the United Nations. (PDF 502Â kb)
Additional file 2: of A case report of spontaneous abortion caused by Brucella melitensis biovar 3
Creators: name: Yang, Hong-Xia
name: Feng, Jun-Jun
name: Zhang, Qiu-Xiang
name: Hao, Rui-E
name: Yao, Su-Xia
name: Zhao, Rong
name: Piao, Dong-Ri
name: Cui, Bu-Yun
name: Jiang, Hai
Publisher: name: figshare
Year: 2018
Subjects: subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Table S1. Product size and repeat unit of 16 loci. (DOCX 68Â kb)
title: Permeability available for VMS source fluids in altered and fractured lavas in the oceanic crust, Semail ophiolite, Oman
Creators: name:  Brett ,   Alannah C.
name:  Diamond ,   Larryn W.
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: The distribution of permeability in the upper oceanic crust controls hydrothermal circulation and the water–rock interactions that feed seafloor mineralization. A prevailing view is that lavas behave as fractured aquifers whose permeability is dominated by major extensional faults flanked by damage zones. Comparatively little is known about the permeability of the km-wide blocks of crust that lie between major faults, yet such blocks constitute huge sources of leachable metals. Our field mapping of hydrothermal veins and pervasive alteration in spreading-axis lavas in the Semail ophiolite enables quantification of the permeability of distal blocks. Fracture length intensities are only ~0.005 m per m2 of outcrop, an order of magnitude lower than in major fault zones. Laboratory measurements show the rock-matrix permeability of lava outcrops is ~2.5 x 10−16 m2. Numerical hydraulic simulations using dfnWorks software yield bulk permeability of ~5 x 10−16 m2 when flow through the fracture network and the rock-matrix are coupled. This demonstrates that the rock-matrix is as permeable as the sparse and unconnected fracture network, consistent with the thoroughly pervasive, rather than fracture-controlled, nature of greenschist-facies hydrothermal alteration observed in the distal Semail lavas. Our observations and calculated bulk permeabilities provide an updated view of fluid flow through the upper crust, in which matrix-flow controls circulation through large blocks of lavas, enhanced by fault-damage zones at km-scale intervals. This new perspective explains how the rock matrix in oceanic lavas is accessible for leaching of metals for seafloor sulphide deposits.
The creative class: do jobs follow people or do people follow jobs?
Creators: name: Østbye, Stein
name: Moilanen, Mikko
name: Tervo, Hannu
name: Westerlund, Olle
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Hematology

description: Regional adjustment models are applied to explore causal interaction between two types of people distinguished by educational attainment, and two types of jobs: creative class jobs and other jobs. Data used are for labour market regions in Finland, Norway and Sweden from the 2000s. Creative class jobs follow people with high educational attainment (one way causation), but creative class jobs also follow other jobs and vice versa (circular causation). The results suggest that stimulating creative class job growth could be accomplished through attracting people with higher education, but also by attracting other jobs with the added benefit that the initial stimulus would be reinforced through circular and cumulative causation between job creation in the two sectors.
Mapping of Calf Death in Japanese Black Cattle
Creators: name: Hirano, Takashi
name: Nishimura, Shota
name: Hara, Hiromi
name: Sugimoto, Yoshikazu
name: Hanzawa, Kei
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Computational Biology

description: Weak calf syndrome (WCS) is a major cause of calf death in Japanese Black cattle. Among IARS disorders, the isoleucyl-tRNA synthetase c.235G>C mutation has been identified as one of the causes of WCS. However, calf deaths differing from those attributed to IARS disorder has been occurring. To identify other genes potentially responsible for these calf deaths, we constructed three populations of three bulls (Bull-1, -2 and -3) that did not carry the IARS mutation, and dead calves (18, 28, and 31 calves) and healthy cattle (18, 15, and 10 cattle) sired by these bulls. The populations were genotyped using the BovineSNP50 BeadChip, but homozygosity mapping did not detect any associated genomic regions with calf death. Linkage analysis performed using each population as a paternal half-sib family of Bull-1, Bull-2, and Bull-3 revealed that, in the Bull-1 population, calf death was mapped to the 8.94 Mb–14.53 Mb and 29.82 Mb–33.77 Mb regions of BTA29. The findings suggested that the incidence of calf death in calves sired by Bull-1 was a hereditary disease exhibiting a dominant, not recessive, inheritance pattern.
Additional file 2: of The impact of blood type O on mortality of severe trauma patients: a retrospective observational study
Creators: name: Takayama, Wataru
name: Endo, Akira
name: Koguchi, Hazuki
name: Sugimoto, Momoko
name: Murata, Kiyoshi
name: Otomo, Yasuhiro
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology

description: Table S1. Multivariate analysis of the factors influencing outcomes and the comparison of explanatory variables. (DOCX 72Â kb)
Forecasting Value at Risk and Expected Shortfall Using a Semiparametric Approach Based on the Asymmetric Laplace Distribution
Creators: name: Taylor, James W.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Value at Risk (VaR) forecasts can be produced from conditional autoregressive VaR models, estimated using quantile regression. Quantile modeling avoids a distributional assumption, and allows the dynamics of the quantiles to differ for each probability level. However, by focusing on a quantile, these models provide no information regarding expected shortfall (ES), which is the expectation of the exceedances beyond the quantile. We introduce a method for predicting ES corresponding to VaR forecasts produced by quantile regression models. It is well known that quantile regression is equivalent to maximum likelihood based on an asymmetric Laplace (AL) density. We allow the density's scale to be time-varying, and show that it can be used to estimate conditional ES. This enables a joint model of conditional VaR and ES to be estimated by maximizing an AL log-likelihood. Although this estimation framework uses an AL density, it does not rely on an assumption for the returns distribution. We also use the AL log-likelihood for forecast evaluation, and show that it is strictly consistent for the joint evaluation of VaR and ES. Empirical illustration is provided using stock index data. Supplementary materials for this article are available online.
Additional file 3: of A case report of spontaneous abortion caused by Brucella melitensis biovar 3
Creators: name: Yang, Hong-Xia
name: Feng, Jun-Jun
name: Zhang, Qiu-Xiang
name: Hao, Rui-E
name: Yao, Su-Xia
name: Zhao, Rong
name: Piao, Dong-Ri
name: Cui, Bu-Yun
name: Jiang, Hai
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: ST sequence data of 9 genes. (DOCX 17Â kb)
MOESM1 of An endogenous microRNA (miRNA1166.1) can regulate photobio-H2 production in eukaryotic green alga Chlamydomonas reinhardtii
Creators: name: Wang, Yuting
name: Zhuang, Xiaoshan
name: Chen, Meirong
name: Zeng, Zhiyong
name: Cai, Xiaoqi
name: Li, Hui
name: Hu, Zhangli
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Additional file 1: Table S1. Primers used in the experiments. Table S2. Total H2 yield of CC-849 and T-miRNA1166.1 transgenic algae before and after heat induction.
Sorption of palladium(II) using organophosphorus derivatives based onthiacalix[4]arene impregnated resins from hydrochloric media
Creators: name: Kunda Uma Maheswara Rao
name: Yamada, Manabu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The sorption kinetics of Pd(II) from hydrochloric acid solutions by 1 and 2 impregnated Amberlite XAD-7 resins (3 and 4) have been systematically studied. Both impregnated resins selectively and efficiently adsorb Pd(II) from single metal solution and automotive catalyst residue solution. In comparison between 3 and 4, 4 showed more efficiency toward Pd(II) with respect to contact time, loading, and stripping capacities. 3 and 4 were characterized by XRD and SEM analyses before and after Pd(II) sorption. We also studied the reusability of 3 and 4 and both the resins offer excellent performance for three times.
Eu3+ Sequestration by Biogenic Nano-Hydroxyapatite Synthesized at Neutral and Alkaline pH
Creators: name: Gangappa, Rajkumar
name: Farrier, Adam
name: Macaskie, Lynne E.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Biogenic hydroxyapatite (bio-HA) has the potential for radionuclide capture and remediation of metal-contaminated environments. Biosynthesis of bio-HA was achieved via the phosphatase activity of a Serratia sp. supplemented with various concentrations of CaCl2 and glycerol 2-phosphate (G2P) provided at pH 7.0 or 8.6. Presence of hydroxyapatite (HA) was confirmed in the samples by X-ray powder diffraction analysis. When provided with limiting (1 mM) G2P and excess (5 mM) Ca2+ at pH 8.6, monohydrocalcite was found. This, and bio-HA with less (1 mM) Ca2+ accumulated Eu(III) to ∼31% and 20% of the biomineral mass, respectively, as compared to 50% of the mineral mass accumulated by commercial HA. Optimally, with bio-HA made at initial pH 7.0 from 2 mM Ca2+ and 5 mM G2P, Eu(III) accumulated to ∼74% of the weight of bio-HA, which was equal to the mass of the HA mineral component of the biomaterial. The implications with respect to potential bio-HA-barrier development in situ or as a remediation strategy are discussed.
Perceived Inflation Persistence
Creators: name: Jain, Monica
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology
subject: FOS: Biological sciences

description: This article constructs and estimates a measure called perceived inflation persistence that can be used to determine if professional forecasters’ inflation forecasts indicate there has been a change in inflation persistence. This measure is built via the implied autocorrelation function that follows from the estimates obtained using a forecaster-specific state-space model. Findings indicate that U.S. perceived inflation persistence has changed since the mid-1990s with more consensus among forecasters at lower levels of persistence. When compared to the autocorrelation function for actual inflation, forecasters typically react less to shocks to inflation than the actual inflation data would suggest.
On the definition and prioritization of strategies and actions to minimize greenhouse gas emissions in cities: An actor-oriented approach
Creators: name: Balouktsi, M.
name: Lützkendorf, T.
Publisher: name: Karlsruhe
Year: 2020

description: Cities as hotspots of human economic activity and infrastructures provide some of the best opportunities for decarbonizing sectors essential for limiting the global warming to 1.5, such as buildings and transport. For this reason, regulators and researchers have widely recognized the necessity to put cities, as an important object of assessment, and city authorities, as an important actor group, at the core of climate mitigation efforts. In their pursuit of a low-emission future, however, cities are confronted with a number of theoretical and practical questions regarding allocation and accounting of city-related greenhouse gas (GHG), target setting and subsequent planning for mitigation. A wide literature is currently focused on the first two. However, to achieve ambitious climate targets, research should urgently focus more on how to reap all available urban mitigation actions and encourage rapid and radical changes. Identifying and prioritising mitigation strategies and actions to achieve the targets, as well as putting them together into a coherent plan with a clear vision of the future, are critical steps in actionable and effective climate action planning. As a first contribution in this direction, this paper provides recommendations for research and practice to support a more integrated and conscious definition and prioritization of actions by municipal stakeholders, based on: (1) the specific context of each city type as a determinant of what actions may work, (2) the executive power of city authority to act as the main actor and (3) the multiple benefits and/or trade-offs accruing from each local climate action.
title: Performance of manganese oxide sorbents for direct lithium extraction from geothermal brines
Creators: name:  Slunitschek ,   Klemens
name:  Kolb ,   Jochen
name:  Eiche,   Elisabeth
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Lithium is one of the critical elements for the realization of electric mobility and energy transition. With a contribution to global Li-production and recycling of less than 1% (2017), Europe depends almost entirely on Li-import. To reduce the dependency, new and unconventional Li resources are explored in the EU. One resource are highly saline brines from geothermal reservoirs of the Upper Rhine Graben (URG), characterized by Li concentrations of up to 200 mg/L. Due to space restrictions, conventional production methods are not suitable and technologies for the direct lithium extraction (DLE), such as Li-Mn oxide sorbents, is needed. Lithium-Mn oxide sorbents have a comparably high Li adsorption capacity and due to ion-sieve properties a high selectivity for Li. Batch experiments with synthetic Li+-solutions and natural geothermal brines were conducted to investigate the sorption capacity and kinetics, and the role of competing ions on Li sorption. The batch experiments reveal fast sorption kinetics with an adsorption of >70% of the maximum Li sorption capacity within several minutes. In relation to Li+-solutions, Li sorption decreases for geothermal brines due to sorption of competing ions. While alkaline metals show a relatively little influence, Mn and Ba are the major competing ions. We prove successfully that Li-extraction from geothermal brines in the URG by Li-Mn oxide sorbents is technologically feasible at the laboratory scale. Upscaling into a pilot plant integrated into a power plant is in progress.
A Study on the Efficacy of an Online Neurofeedback Game using Consumer-grade EEG on Enhancing Attention Skills in Stroke and Mild Cognitive Impairment Patients
Creators: name: T.A., Suhail
name: R., Subasree
name: Achutavarrier Prasad, Vinod
Publisher: name: Singapore Institute of Technology
Year: 2024
Subjects: classificationCode: 401803
subject: Nanoelectromechanical systems

description: The burden of cognitive impairment is increasing worldwide and the rehabilitation of patients with such disorders is a major concern. Neurofeedback training (NFT) is emerging as a promising non-pharmacological intervention for enhancing cognition in healthy and cognitive-deficit patients. In this paper, we examine the efficacy of a real-time neurofeedback game using a four-channel consumer-grade Electroencephalography (EEG) system on enhancing overt and covert attention skills in Stroke and Mild cognitive impairment (MCI) patients. The game works based on navigating a car on a computer screen using the player’s attention level computed from EEG signals streamed in real-time. The proposed NFT is conducted across 18 patients (10 Stroke and 8 MCI). The attention score significantly improved from the first session to the final session by 1.25-12.55% in the stroke group and 1.84-44.14% in the MCI group. The experimental results demonstrate that the proposed neurofeedback game using consumer-grade EEG is an effective tool for enhancing overt and covert attention skills in patients with cognitive impairment. To our knowledge, this is the first EEG-Brain Computer Interface study for improving overt and covert attention on the cross-sectional stroke-MCI patients.
Sorption of palladium(II) using organophosphorus derivatives based on thiacalix[4]arene impregnated resins from hydrochloric media
Creators: name: Kunda Uma Maheswara Rao
name: Yamada, Manabu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The sorption kinetics of Pd(II) from hydrochloric acid solutions by 1 and 2 impregnated Amberlite XAD-7 resins (3 and 4) have been systematically studied. Both impregnated resins selectively and efficiently adsorb Pd(II) from single metal solution and automotive catalyst residue solution. In comparison between 3 and 4, 4 showed more efficiency towards Pd(II) with respect to contact time, loading and stripping capacities. 3 and 4 were characterized by XRD and SEM analysis before and after Pd (II) sorption. We also studied the reusability of 3 and 4 and both the resins offers excellent performance for three times.
Diisopropylethylammonium acetate (DIPEAc): An efficient and recyclable catalyst for the rapid synthesis of 5-substituted-1H-tetrazoles
Creators: name: Bhosle, Manisha R.
name: Dastgir S. Shaikh
name: Khillare, Lalit D.
name: Amarsinh R. Deshmukh
name: Ramrao A. Mane
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: A simple and efficient protocol developed for the synthesis of 5-substituted 1H-tetrazole derivatives through [2+3] cycloaddition reaction between benzonitriles and sodium azide using diisopropylethylammonium acetate as a recyclable reaction medium is described. The reactions proceed well at 80 °C and provide the corresponding tetrazoles in good to excellent yields (up to 94% yield). Developed method has notable advantages, such as simple and mild conditions, easy workup, reusability with consistent catalytic activity, and safer alternative to hazardous, corrosive conventional Lewis acid catalysts.
Facile synthesis of 4″-O-alkyl-(–)-EGCG derivatives through regioselective deacetylative alkylation
Creators: name: Seo, Yujin
name: Kim, Mi Kyoung
name: Hyunah Choo
name: Youhoon Chong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Therapeutic potential of the D-ring methyl ethers of (–)-epigallocatechin-3-gallate [(–)-EGCG] warrants extensive structure–activity relationship study of various D-ring ethers of (–)-EGCG but, for this purpose, efficient synthetic strategy needs to be developed. In this study, efficient preparation of the 4″-O-alkyl-(–)-EGCGs (4a–e) was demonstrated using KI/K2CO3-promoted deacetylative alkylation of peracetyl (–)-EGCG, which could be broadly utilized for the preparation of various D-ring alkyl ethers of (–)-EGCG and thereby extensive structure–activity relationship study.
Eu3+ sequestration by biogenic nano-hydroxyapatite synthesised at neutral and alkaline pH
Creators: name: Gangappa, Rajkumar
name: Farrier, Adam
name: Macaskie, Lynne E.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Biogenic hydroxyapatite (bio-HA) has the potential for radionuclide capture and remediation of metal contaminated environments. Biosynthesis of bio-HA was achieved via the phosphatase activity of a Serratia sp. supplemented with various concentrations of CaCl2 and glycerol 2- phosphate (G2P) provided at pH 7.0 or 8.6. Hydroxyapatite (HA) was confirmed in the samples by X-ray powder diffraction analysis. When provided with limiting (1 mM) G2P and excess (5 mM) Ca2+ at pH 8.6 monohydrocalcite was found. This, and bio-HA with less (1 mM) Ca2+ accumulated Eu(III) to ∼31% and 20% of the biomineral mass respectively as compared to 50% of the mineral mass accumulated by commercial HA. Optimally, with bio-HA made at initial pH 7.0 from 2 mM Ca2+ and 5 mM G2P, Eu(III) accumulated to ∼74% of the weight of bio-HA which was equal to the mass of the HA mineral component of the biomaterial. The implications with respect to potential bio-HA-barrier development in situ or as a remediation strategy are discussed.
Facile Synthesis of 4″–O–Alkyl (–)-EGCG Derivatives through Regioselective Deacetylative Alkylation
Creators: name: Seo, Yujin
name: Kim, Mi Kyoung
name: Hyunah Choo
name: Youhoon Chong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Therapeutic potential of the D–ring methyl ethers of (–)–epigallocatechin–3–gallate ((–)–EGCG) warrants extensive structure–activity relationship study of various D–ring ethers of (–)–EGCG but, for this purpose, efficient synthetic strategy needs to be developed. In this study, efficient preparation of the 4″–O–alkyl–(–)–EGCGs (4a–4e) was demonstrated by employing KI/K2CO3–promoted deacetylative alkylation of peracetyl (–)–EGCG, which could be broadly utilized for preparation of various D–ring alkyl ethers of (–)–EGCG and thereby extensive structure–activity relationship study.
Diisopropyl Ethylammonium Acetate (DIPEAc): An Efficient and Recyclable Catalyst for the Rapid Synthesis of 5-Substituted-1 H-Tetrazoles
Creators: name: Bhosle, Manisha R.
name: Dastgir S. Shaikh
name: Khillare, Lalit D.
name: Amarsinh R. Deshmukh
name: Ramrao A. Mane
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: A simple and efficient protocol developed for the synthesis of 5-substituted 1H-tetrazole derivatives via [2 + 3] cycloaddition reaction between benzonitriles and sodium azide using diisopropyl ethylammonium acetate as a recyclable reaction medium is described. The reactions proceed well at 80 °C and provide the corresponding tetrazoles in good to excellent yields (up to 94% yield). Developed method has notable advantages, such as simple and mild conditions, easy workup, reusability with consistent catalytic activity and safer alternative to hazardous, corrosive conventional lewis acid catalysts.
Use of Molecular Techniques to Confirm Nonnative Fish Predation on Razorback Sucker Larvae in Lake Mohave, Arizona and Nevada
Creators: name: Ehlo, Chase A.
name: Saltzgiver, Melody J.
name: Dowling, Thomas E.
name: Marsh, Paul C.
name: Kesner, Brian R.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Larval predation by nonnative fishes has long been implicated in the decline of western native large-river fishes, but visual assessment of predation is difficult due to the postconsumption degradation of fragile larvae. Molecular techniques were used to demonstrate predation on the larvae of endangered Razorback Suckers Xyrauchen texanus by nonnative juvenile centrarchids in field samples from Lake Mohave, Arizona–Nevada, where larvae are seasonally abundant. Razorback Sucker DNA was detected in the gut contents of 7% and 9% of Bluegills Lepomis macrochirus and in 14% and 15% of Green Sunfish L. cyanellus that were captured during spring 2014 and 2015, respectively. There was no significant (α = 0.05) effect of predator TL, predator species, or year on the presence of larval DNA. Juvenile centrarchids have the potential to consume substantial numbers of Razorback Sucker larvae and thus to impact recruitment. The control of nonnative fishes may be impractical, but a viable alternative for mitigation of their impacts is to provide nonnative-free refugia for native large-river fishes. Received June 17, 2016; accepted September 19, 2016 Published online January 19, 2017
Efficient recovery of ionic liquid by electrodialysis in the acid hydrolysis process
Creators: name: Endo, Takatsugu
name: Tatsumi, Mai
name: Kuroda, Kosuke
name: Heri Satria
name: Shimada, Yumiko
name: Ninomiya, Kazuaki
name: Takahashi, Kenji
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Electrodialysis (ED) has been recently known as a highly effective technique to remove and recover ionic liquids from aqueous solution. When a conventional electrolyte solution for the ED process containing Na2SO4 was used, a recovery ratio of an acidic IL, 1-butyl-3-methylimidazolium hydrogen sulfate ([Bmim][HSO4]), was 90%. On the other hand, the value clearly increased to 96% when we employed [Bmim][HSO4] as the electrolyte solution. In an acid hydrolysis of bagasse using the IL under microwave irradiation, the recovery ratio maintains 96%, irrespective of reaction time. This demonstrates the applicability of the proposed ED system in biomass processing.
Probing the binding of Azilsartan to DNA by molecular docking, steady-state/time-resolved fluorescence, viscosity, infrared, and circular dichroism spectra
Creators: name: Yanmei Huang
name: Wang, Qing
name: Hongqin Yang
name: Tang, Bin
name: Xiangling Ma
name: Jiawei He
name: Li, Hui
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Azilsartan, a new antihypertensive drug, has effects on the sympathetic nervous system and expression of genes. The interaction of Azilsartan with DNA was investigated using molecular docking and multi-spectral techniques. Molecular docking revealed that Azilsartan could interact with DNA via groove binding from a theoretical perspective. Time-resolved fluorescence measurements indicated that the quenching mechanism was static, and further analysis of quenching data demonstrated that the binding was spontaneous and mainly driven by hydrophobic forces. The results of interaction with denatured DNA, viscosity, infrared spectroscopy, and circular dichroism showed that Azilsartan could bind to DNA through groove binding, which was consistent with docking analyses.
Probing the Binding of Azilsartan to DNA by Molecular Docking, Steady-State/Time-Resolved Fluorescence, Viscosity, Infrared, and Circular Dichroism Spectra
Creators: name: Yanmei Huang
name: Wang, Qing
name: Hongqin Yang
name: Tang, Bin
name: Xiangling Ma
name: Jiawei He
name: Li, Hui
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Azilsartan, a new antihypertensive drug, has effects on sympathetic nervous system and expression of genes. The interaction of Azilsartan with DNA was investigated using molecular docking and multi-spectral techniques. Molecular docking revealed Azilsartan could interact with DNA via groove binding from theoretical perspective. Time-resolved fluorescence measurements indicated that the quenching mechanism was static, and further analysis of quenching data demonstrated the binding was spontaneous and mainly driven by hydrophobic forces. The results of interaction with denatured DNA, viscosity, infrared spectroscopy, and circular dichroism showed that Azilsartan could bind to DNA through groove binding, which was consistent with docking analyses.
Efficient recovery of ionic liquid by electrodialysis in acid hydrolysis process
Creators: name: Endo, Takatsugu
name: Tatsumi, Mai
name: Kuroda, Kosuke
name: Heri Satria
name: Shimada, Yumiko
name: Ninomiya, Kazuaki
name: Takahashi, Kenji
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Electrodialysis (ED) has been recently known as a highly effective technique to remove and recover ionic liquids from aqueous solution. When a conventional electrolyte solution for ED process containing Na2SO4 was used, a recovery ratio of an acidic IL, 1-butyl-3-methylimidazolium hydrogen sulfate ([Bmim][HSO4]), was 90%. On the other hand, the value clearly increased to 96% when we employed [Bmim][HSO4] as the electrolyte solution. In an acid hydrolysis of bagasse using the IL under microwave irradiation the recovery ratio maintains 96%, irrespective of reaction time. This demonstrates the applicability of the proposed ED system in biomass processing.
Vitamin D status, aeroallergen sensitization, and allergic rhinitis: A systematic review and meta-analysis
Creators: name: Aryan, Zahra
name: Rezaei, Nima
name: Camargo, Carlos A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Purpose: The role of vitamin D status in the etiology of allergic diseases is uncertain. The aim of this study was to investigate the association of vitamin D status with risk of two main outcomes: aeroallergen sensitization and allergic rhinitis (AR). Methods: We performed a systematic review of Medline, Scopus, Science Citation Index, and Google Scholar databases. Studies were included if they reported on prevalent or incident cases of aeroallergen sensitization or AR according to vitamin D status. Quality assessment, data extraction and meta-analysis were performed. Results: A total of 21 observational studies were included. Children with serum 25(OH)D ≥75 nmol/L had significantly reduced odds of aeroallergen sensitization, but neither vitamin D intake in pregnancy nor vitamin D supplementation in infancy were associated with risk of AR. Individuals with serum 25(OH)D ≥75 nmol/L had lower prevalence of AR compared to those with serum 25(OH)D <50 nmol/L (OR; 0.71, 95%CI; (0.56-0.89), p = 0.04). This association was mainly observed in adult men; prevalence of AR was lower in men with serum 25(OH)D ≥75 nmol/L compared to men with serum 25(OH)D <50 nmol/L, while this association was not observed in women. Conclusions: The current literature suggests significant age- and sex-specific relations of vitamin D status to risk of aeroallergen sensitization and AR.
Supplementary Tables S1 - S5 and Figure S1 from Incubation behaviours of oviraptorosaur dinosaurs in relation to body size
Creators: name: Tanaka, Kohei
name: K. Zelenitsky, Darla
name: Lü, Junchang
name: DeBuhr, Christopher L.
name: Yi, Laiping
name: Jia, Songhai
name: Ding, Fang
name: Xia, Mengli
name: Liu, Di
name: Shen, Caizhi
name: Chen, Rongjun
Publisher: name: The Royal Society
Year: 2018

description: Table S1: Mid- to Upper Cretaceous oviraptorosaur egg and clutch specimens examined in this study; Table S2: Results of regression analyses for clutch volume (mm3, in logarithmic scale) against adult body mass (kg, in logarithmic scale) in living crocodylian and precocial bird species (n = 180) in order to predict adult body mass for the elongatoolithid specimens; Table S3: Outer and inner clutch diameters of various oviraptorosaur egg taxa; Table S4: Eggshell thickness of various oviraptorosaur egg taxa; Table S5: Eggshell porosity and predicted nest type in various oviraptorosaur egg taxa; Figure S1. Comparisons of egg shape in oviraptorosaurs.
Modeling and Optimization of Reactive Extraction of Gallic Acid Using RSM
Creators: name: Rewatkar, Kalpana
name: Diwakar Z. Shende
name: Kailas L. Wasewar
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Plant Biology

description: Reactive extraction was experimentally investigated for recovery of gallic acid (GA) from the aqueous solution using tri-n-octylamine (TOA) as extractant in hexanol. All experiments were carried out according to statistical design in order to develop a regression model used to optimize the extraction of GA. Two independent variables were selected as: initial concentration of GA (CGA0) in aqueous phase and concentration of TOA (CTOA) in organic phase. The statistical analysis showed that both the independent variables had significant effect on response value, followed by the quadratic and interactive effect on response. A five-level central composite rotatable design (CCRD) was employed. Analysis of variance (ANOVA) showed a high coefficient of determination (R2 = 99.0%). The optimal extraction conditions of GA were determined as: CGA0 = 2.01 g/L, CTOA = 6.8% v/v. At the optimum conditions, the experimental yield of GA was 91.9%, which was in close agreement with the predicted value of 93.2%.
Validity and reliability of a questionnaire to assess social skills in traumatic brain injury: A preliminary study
Creators: name: Francis, Heather M.
name: Osborne-Crowley, Katherine
name: McDonald, Skye
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Objective: To describe the reliability and validity of a new measure, the Social Skills Questionnaire for Traumatic Brain Injury (SSQ-TBI). Methods: Fifty-one adults with severe TBI completed the SSQ-TBI questionnaire. Scores were compared to informant- and self-report on questionnaires addressing frontal lobe mediated behaviour, as well as performance on an objective measure of social cognition and neuropsychological tasks, in order to provide evidence of concurrent, divergent and predictive validity. Results: Internal consistency was excellent at α = 0.90. Convergent validity was good, with informant ratings on the SSQ-TBI significantly correlated with Neuropsychiatric Inventory Disinhibition sub-scales (r = 0.50–63), the Current Behaviour Scale (r = 0.39–0.48) and Frontal Systems Behaviour Scale (r = 0.60–0.83). However, no relationship was seen with an objective measure of social skills or neuropsychological tasks of disinhibition. There was a significant relationship with real-world psychosocial outcomes on the Sydney Psychosocial Reintegration Scale-2 (r = –0.38––0.69) Conclusions: This study provides preliminary findings of good internal consistency and convergent and predictive validity of a social skills questionnaire adapted to be appropriate for individuals with TBI. Further assessment of psychometric properties such as test–re-test reliability and factor structure is warranted.
title: HTK-N: Modified Histidine-Tryptophan-Ketoglutarate Solution—A Promising New Tool in Solid Organ Preservation
Creators: name: Mohr, Annika
name: Brockmann, Jens G.
name: Becker, Felix
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2022
Subjects: subject: 610 Medicine and health

description: To ameliorate ischemia-induced graft injury, optimal organ preservation remains a critical hallmark event in solid organ transplantation. Although numerous preservation solutions are in use, they still have functional limitations. Here, we present a concise review of a modified Histidine-Tryptophan-Ketoglutarate (HTK) solution, named HTK-N. Its composition differs from standard HTK solution, carrying larger antioxidative capacity and providing inherent toxicity as well as improved tolerance to cold aiming to attenuate cold storage injury in organ transplantation. The amino acids glycine, alanine and arginine were supplemented, N-acetyl-histidine partially replaced histidine, and aspartate and lactobionate substituted chloride. Several in vitro studies confirmed the superiority of HTK-N in comparison to HTK, being tested in vivo in animal models for liver, kidney, pancreas, small bowel, heart and lung transplantation to adjust ingredients for required conditions, as well as to determine its innocuousness, applicability and potential advantages. HTK-N solution has proven to be advantageous especially in the preservation of liver and heart grafts in vivo and in vitro. Thus, ongoing clinical trials and further studies in large animal models and consequently in humans are inevitable to show its ability minimizing ischemia-induced graft injury in the sequel of organ transplantation.
description: Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).