cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Psychosis at the Beginning: Detecting, Understanding, and Treating: Focus on the Clinical High Risk concept
Creators: name: Curtis, Logos Simian
Publisher: name: Université de Genève
Year: 2021
Subjects: info:eu-repo/classification/ddc/616.89
Psychosis
DUP
Duration of Untreated Psychosis
Psychosis Prodrome
ARMS
At Risk Mental State
UHR
Ultra High Risk
CHR
Clinical High Risk
CHR-P
Clinical High Risk Psychosis
Clinical Staging Psychiatry

description: Psychoses are one of the main groups of mental disorders. Based on the observation that initial treatment delay for psychoses often led to poor prognosis, an interest was born in identifying and defining early psychotic stages, currently termed the Clinical High Risk (CHR) concept. Representing early stages of psychosis with a risk of progressing to more advanced stages, different types of risk groups were defined. The CHR concept also allowed for the proposal and development of a staging concept as applied to psychotic disorders. The CHR concept, particularly through the staging system, has also enhanced our biological understanding of psychosis as biological processes altered in psychosis, such as striatal dopamine or cortical thinning, which can in many cases be shown to progress across stages. This may in turn allow for better identification of biological treatment opportunities, and also facilitate the development of reliable biomarkers for psychosis.
Fig. S1. Early Andean tectonomagmatic stages in north Patagonia: insights from field and geochemical data
Creators: name: Echaurren, Andrés
name: Oliveros, Verónica
name: Folguera, Andrés
name: Ibarra, Federico
name: Creixell, Christian
name: Lucassen, Friedrich
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Fig. S1. Petrographic thin-sections of the Lago la Plata Formation from samples (a): BG-01, (b): BG-02, (c): BG-03 and (d): CLC-01. See samples location in Table 1.
Complications of diabetes and their management
Creators: name: Gariani, Karim
Publisher: name: Université de Genève
Year: 2021
Subjects: info:eu-repo/classification/ddc/616
Diabetes
Complications
Management

description: Diabetes mellitus (DM) is widely acknowledged to be an emerging epidemic in essentially all areas of the world. It currently affects approximately 415 million people, and this number is expected to increase to 650 million by the year 2040. A consequence of the increasing prevalence of DM that is of great concern is the parallel increase in diabetes-related complications and their pronounced impact on the quality of life and on economic costs. Diabetes complications are typically divided into macrovascular complications that include peripheral vascular disease, coronary heart disease, and stroke and microvascular complications that include retinopathy, neuropathy, and end-stage renal disease (ESRD). Despite the prevalence and the burden of DM, there are still a significant number of unmet needs in the management of diabetes-related complications. We here highlight the specific aspect of diabetic foot infection (DFI) management. DFI represents a significant source of morbidity for diabetics. The lifetime risk of DFI in diabetics may be as high as 25%, and DFI is among the most common diabetes-related causes of hospitalization with -unfortunately- a pronounced increased risk of amputation. By examining the clinical pathway for adult patients, we assessed factors related to remission of infection, with a focus on antibiotic-related variables. We also evaluated the efficacy of oral amoxicillin-clavulanate (AMC) for oral therapy of diabetic foot infections, especially for diabetic foot osteomyelitis (DFO). We also studied other diabetes-related complications and their management by evaluation of the pharmacological strategy in diabetic nephropathy and exercise in non-alcoholic fatty liver disease (NAFLD). Finally, we explored the possibility of previously unidentified diabetes-associated disorders by assessment of the association between diabetes and the risk of venous thromboembolism (VTE).
Supplementary Data. Early Andean tectonomagmatic stages in north Patagonia: insights from field and geochemical data
Creators: name: Echaurren, Andrés
name: Oliveros, Verónica
name: Folguera, Andrés
name: Ibarra, Federico
name: Creixell, Christian
name: Lucassen, Friedrich
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Supplementary Data: Petrographic descriptions and geochemical–isotopic data.
Fig. S2. Early Andean tectonomagmatic stages in north Patagonia: insights from field and geochemical data
Creators: name: Echaurren, Andrés
name: Oliveros, Verónica
name: Folguera, Andrés
name: Ibarra, Federico
name: Creixell, Christian
name: Lucassen, Friedrich
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Fig. S2. Petrographic thin-sections of the Divisadero Group from samples (a): CC-01, (b): CC-02, (c): CC-03 and (d) GOB-01. See samples location in Table 1.
How does porosity heterogeneity affect the transport properties of multibore filtration membranes?
Creators: name: Wypysek, Denis
name: Rall, Deniz
name: Neef, Tobias
name: Jarauta, Alex
name: Secanell, Marc
name: Wessling, Matthias
Publisher: name: arXiv
Year: 2022
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The prediction of pressure and flow distributions inside porous membranes is important if the geometry deviates from single-bore tubular geometries. This task remains challenging, especially when considering local porosity variations caused by lumen- and shell-side membrane skins and macro- and micro-void structures, all of them present in multibore membranes. This study analyzes pure water forward and reverse permeation and backwashing phenomena for a polymeric multibore membrane with spatially-varying porosity and permeability properties using computational fluid dynamics simulations. The heterogeneity of porosity distribution is experimentally characterized by scanning electron microscopy scans and reconstructed cuboids of X-ray micro-computed tomography scans. The reconstructed cuboids are used to determine porosity, pore size distribution, and intrinsic permeability in the membrane's porous structure in all spatial directions. These position-dependent properties are then applied to porous media flow simulations of the whole membrane domain with different properties for separation layer, support structure, and outside skin layer. Various cases mimicking the pure water permeation, fouling, and backwashing behavior of the membrane are simulated and compared to previously obtained MRI measurements. This work reveals (a) anisotropic permeability values and isoporosity in all directions and (b) differing contributions of each lumen channel to the total membrane performance, depending on the membrane-skin's properties. This study encourages to pertain the quest of understanding the interaction of spatially distributed membrane properties and the overall membrane module performance of multibore membranes.
NanoCommons - Opportunities for accessing nanoinformatics and predictive models for environmental fate.
Creators: name: Walker, Lee
name: Matzke, Marianne
name: Lofts, Steve
name: Svendsen, Claus
Publisher: name: Zenodo
Year: 2020
Subjects: Transnational Access, services, research infrastructure, nanosafety, data management

description: Here we present the three services that CEH offers through NanoCommons
 transnational access that include: (i) Ecotoxicological Laboratory Workflows, (ii) Data processing & analysis (EcoToxicology), and (iii) Predictive Eco-NanoToxicology.
A 5-dimensional patient education for Type 2 diabetes remission
Creators: name: Lagger, Grégoire
Publisher: name: Université de Genève
Year: 2021
Subjects: info:eu-repo/classification/ddc/616
Patient education
Empowerment
Patient learning
Diabetes mellitus
Type 1 diabetes
Type 2 diabetes
Disease control
Reversal
Remisison
Cure

description: In this thesis we propose a 5-dimensional therapeutic patient education (TPE) programme for the reversal of metabolic diseases such as T2D. It draws the links between learning about one's disease and improving one's health and expands this to a model for the transformation of the person. Several dimensions of a human's learning and transformation process, including the cognitive, affective and perceptive dimensions, are considered in this model. Addressing these elements increases the patient's ability to undertake a learned approach to improving his/her health and thus gain in free will and quality of life. The proposed TPE programme could lead to more efficient personalized patient education, institutional group teaching or public health programmes. It represents the first integrative scheme for the reversal of T2D and other metabolic diseases and can be transferred worldwide and at a low cost.
Additional file 5: of Chloroplast genome analyses and genomic resource development for epilithic sister genera Oresitrophe and Mukdenia (Saxifragaceae), using genome skimming data
Creators: name: Liu, Luxian
name: Wang, Yuewen
name: He, Peizi
name: Li, Pan
name: Lee, Joongku
name: Soltis, Douglas
name: Fu, Chengxin
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: Plant Biology

description: Figure S2. Summary of STRUCTURE analyses based on the gSSR data. (A) Mean ln posterior probabilities of each K, LnP(D). (B) The corresponding Î K statistics calculated according to Evanno et al. (2005). (PDF 354 kb)
Effects of postharvest methyl jasmonate treatment on aromatic volatile biosynthesis by ‘Nanguoli’ fruit at different harvest maturity stages
Creators: name: G. H. Qin
name: S. W. Wei
name: S. T. Tao
name: H. P. Zhang
name: W. J. Huang
name: G. F. Yao
name: S. F. Sha
name: S. L. Zhang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology
subject: Plant Biology
subject: 60506 Virology

description: The ripe fruit of Pyrus ussuriensis ‘Nanguoli’ is favoured by people for its attractive colour, exquisite flesh and pleasant flavour. However, its flavour is negatively affected by early harvest. Therefore, this study aimed to determine whether exogenous methyl jasmonate (MJ) can help to regulate aromatic volatiles biosynthesis in pre-climacteric ‘Nanguoli’ fruit at different maturity stages (135 days after full bloom (DAFB) or ‘early harvested’ and 145 DAFB or ‘normal harvested’). MJ promoted aromatic volatile biosynthesis in normal harvested fruit, with the number of volatile compounds increasing from 43 in untreated fruit to 51 and 57 in fruit that had been treated with 1 and 5 mM MJ, respectively. By contrast, MJ had little effect on early harvested fruit, which exhibited an increase from 41 to 49 and 44 volatile compounds following treatment with 1 and 5 mM MJ, respectively. The total content of aromatic volatiles also increased by 53.75% and 66.82% in normal harvested fruit treated with 1 and 5 mM MJ, respectively, whereas early harvested fruit exhibited only slight increases. There was no significant difference between the effects of 1 and 5 mM MJ on aromatic volatile biosynthesis, indicating that the observed effects were dependent on the maturity stage of the fruit rather than the exogenous MJ concentration within the range tested. The ethylene production rate exhibited similar changes to those observed for the aromatic volatile content and there were no significant differences in the aromatic volatile contents of ‘Nanguoli’ fruits that had been treated with 1-methylcyclopropene (1-MCP) + MJ at different maturity stages. Therefore, it is deduced that ethylene may trigger aromatic volatile biosynthesis.
Additional file 6: of Chloroplast genome analyses and genomic resource development for epilithic sister genera Oresitrophe and Mukdenia (Saxifragaceae), using genome skimming data
Creators: name: Liu, Luxian
name: Wang, Yuewen
name: He, Peizi
name: Li, Pan
name: Lee, Joongku
name: Soltis, Douglas
name: Fu, Chengxin
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Hematology
subject: Plant Biology

description: Table S4. cpSSRs identified from comparative analysis of chloroplast genome for Oresitrophe and Mukdenia. (DOCX 22 kb)
Precision Medicine in Inflammatory Bowel Disease
Creators: name: Restellini, Sophie
Publisher: name: Université de Genève
Year: 2021
Subjects: info:eu-repo/classification/ddc/616
Maladies inflammatoires chroniques intestinales
Médecine de précision
Therapeutic drug monitoring
IBD

description: Inflammatory bowel diseases (IBD) are immune-mediated diseases with complex pathogenesis. IBD's course is heterogeneous, as is the response of patients to drugs, but physicians often take a “one size-fits-all” approach. Many patients do not respond to their first treatment, lose response, or suffer adverse events caused by medications. The need to manage patients individually, through precision medicine, is clear. Personalizing IBD treatment depends on determining which patients are at high risk of adverse complications, choosing the best therapy for each patient and optimizing treatment efficacy through tight and tailored monitoring. To change the natural course of disease, an individual's prognosis rather than their symptoms should guide therapy. This thesis outlines current knowledge of IBD pathogenesis and discusses the use of precision medicine to manage IBD patients, with the goal of improving the quality of clinical practice through targeted care.
ЭКСПЕРИМЕНТАЛЬНОЕ ИЗУЧЕНИЕ ВЛИЯНИЯ ЧАСТИЦ ВИЗУАЛИЗАТОРА НА КОНВЕКЦИЮ И ТЕПЛОПЕРЕНОС В ВИБРИРУЮЩЕЙ ПОЛОСТИ
Creators: name: КОЗЛОВ В.Г.
name: РЫСИН К.Ю.
name: ВЯТКИН А. А.
Publisher: name: Конвективные течения
Year: 2019
Subjects: ПЛОСКИЙ СЛОЙ
КРУГОВЫЕ ВИБРАЦИИ
ВИБРАЦИОННАЯ ТЕПЛОВАЯ КОНВЕКЦИЯ
КОНВЕКТИВНЫЕ СТРУКТУРЫ
PLANE LAYER
CIRCULAR VIBRATIONS
THERMAL VIBRATIONAL CONVECTION
CONVECTIVE STRUCTURES

description: Экспериментально исследуется вибрационная тепловая конвекция в горизонтальном плоском слое, совершающем круговые поступательные колебания в своей плоскости. Обнаружено, что в зависимости от концентрации и типа трассеров, которые добавлены в жидкость для визуализации конвективных потоков, структура наблюдаемых в слое течений изменяется. В частности, наличие в жидкости сравнительно малого количества визуализатора, используемого при изучении поля скоростей PIV-методом, приводит к генерации конвективных потоков и значительной интенсификации теплопереноса до порога возникновения вибрационной конвекции в слое, подогреваемом сверху.
Age-Related Macular Degeneration and Mortality: A Systematic Review and Meta-Analysis
Creators: name: McGuinness, Myra B.
name: Karahalios, Amalia
name: Finger, Robert P.
name: Guymer, Robyn H.
name: Simpson, Julie A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Purpose: Age-related macular degeneration (AMD) is the leading cause of severe, irreversible vision loss in older adults. Evidence for an association between AMD and mortality remains inconclusive despite evidence for an association with cardiovascular and inflammatory diseases. We aim to compare all-cause, cardiovascular and cancer mortality between those with early or late AMD and control study participants. Methods: A protocol was registered at PROSPERO (CRD42015020622). A systematic search of Medline (Ovid), PubMed, and Embase (Ovid) was conducted on 6 June 2015. Reference lists from identified studies and four clinical trial registries were searched for additional studies. Participants were required to be over the age of 40 years, and AMD status must have been objectively assessed. The Risk Of Bias In Non-Randomized Studies – of Interventions (ROBINS-I) tool was used to assess the risk of bias. Random-effects meta-analyses were performed. Results: A total of 12 reports from 10 studies were included in the meta-analysis. Late AMD was associated with elevated rates of all-cause (nine studies, hazard ratio (HR) 1.20, 95% confidence interval, CI, 1.02–1.41) and cardiovascular mortality (six studies, HR 1.46, 95% CI 1.13–1.98), but early AMD was not (all-cause mortality, 10 studies, HR 1.06, 95% CI 0.98–1.14; cardiovascular mortality, five studies, HR 1.12, 95% CI 0.96–1.31). There was no evidence of an association between early or late AMD and cancer mortality (early AMD, three studies, HR 1.17, 95% CI 0.78–1.75; late AMD, three studies, HR 1.01, 95% CI 0.77–1.33). Conclusion: Late AMD is associated with increased rates of all-cause and cardiovascular mortality, suggesting shared pathways between late AMD and systemic disease.
ТЕПЛОВАЯ КОНВЕКЦИЯ В ЦИЛИНДРИЧЕСКОМ СЛОЕ С ПРОДОЛЬНОЙ ПЕРЕГОРОДКОЙ ПРИ МОДУЛИРОВАННОМ ВРАЩЕНИИ
Creators: name: ВЯТКИН А.А.
name: САБИРОВ Р.Р.
Publisher: name: Конвективные течения
Year: 2019
Subjects: ТЕПЛОВАЯ КОНВЕКЦИЯ
ОДНОСВЯЗНЫЙ ЦИЛИНДРИЧЕСКИЙ СЛОЙ
ВРАЩАТЕЛЬНЫЕ ВИБРАЦИИ
ВРАЩЕНИЕ
THERMAL CONVECTION
SIMPLY CONNECTED CYLINDRICAL LAYER
ROTATIONAL VIBRATION
ROTATION

description: Экспериментально исследуется тепловая конвекция жидкости в односвязном горизонтальном цилиндрическом слое, вращающемся с переменной скоростью. Внутренняя граница слоя имеет более высокую температуру. Кювета совершает быстрое вращение, при этом жидкость устойчиво стратифицирована в центробежном силовом поле, а поле силы тяжести не сказывается. Скорость вращения модулируется с высокой частотой. Параметры эксперимента отвечают условиям, когда инерционные волны не возбуждаются (частота вибраций более чем вдвое превосходит частоту вращения полости). Изучены пороги возникновения тепловой конвекции и структуры конвективных потоков в зависимости от скорости вращения и параметров вращательных вибраций полости. Обнаружено пороговое возбуждение тепловой конвекции, не связанное с действием механизма маятниковой вибрационной конвекции. В полости наблюдается система тороидальных валов, пространственный период которых соизмерим с толщиной слоя.
ОСРЕДНЕННЫЕ ТЕЧЕНИЯ В СФЕРИЧЕСКОМ КОНТЕЙНЕРЕ С КОЛЕБЛЮЩЕЙСЯ ЭЛАСТИЧНОЙ СТЕНКОЙ
Creators: name: КОЗЛОВ Н.В.
Publisher: name: Конвективные течения
Year: 2019
Subjects: СФЕРИЧЕСКАЯ ПОЛОСТЬ
ОСРЕДНЕННЫЕ ТЕЧЕНИЯ
КОЛЕБАНИЯ
ДЕФОРМИРУЕМАЯ ГРАНИЦА
SPHERICAL CAVITY
STEADY STREAMING
OSCILLATIONS
ELASTIC BOUNDARY

description: Экспериментально исследуются течения вязкой жидкости в сферической полости с эластичной границей, совершающей гармонические осесимметричные колебания. Колебания вдоль горизонтальной оси задаются при помощи двух линейных двигателей. Структура течений изучается посредством трассерной визуализации (PIV). Рассматривается диапазон низких и умеренных безразмерных частот. В указанном диапазоне наблюдается формирование осредненных течений в виде двух тороидальных вихрей. Изучается их интенсивность, проводится анализ влияния положения узлов колебаний границы на структуру.
Monitoring the Microbial Conditions in Breweries in Yangtze River Delta Region, China
Creators: name: Zheng, Feiyun
name: Niu, Chengtuo
name: Tang, Dongjian
name: Liu, Chunfeng
name: Li, Yongxian
name: Wang, Jinjing
name: Li, Qi
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: This study aimed to investigate the contamination degree and quality control of seven breweries from the Yangtze River Delta region, China. A total of 205 spoilage bacteria strains were isolated and no wild yeast was observed. The vast majority of the spoilage bacteria belonged to Lactobacillus, Lactococcus, and Leuconostoc species and 28.8% of them could grow in beer. Among the seven sampling points, fermented beer, finished beer, and equipment contained larger amounts of spoilage bacteria. The most abundant of the spoilage bacteria that could grow in beer existed in fermented beer and the number of spoilage bacteria was significantly reduced in the finished beer. The equipment in fermentation and packaging workshops showed high percentages of spoilage bacteria that could grow in beer. This indicated that more attention should be paid in controlling the spoilage bacteria in the fermentation and packaging processes. The hop tolerance related gene analysis showed that the majority of spoilage bacteria contained at least one of the HorA, HorC and HitA genes. None of these genes were observed in the two spoilage bacteria strains that could grow in the beer. This information could be useful for breweries in the Yangtze River Delta region for removing risks in order to produce high-quality products in good microbial condition.
Additional file 1: of High frequency of the TARDBP p.M337Â V mutation among south-eastern Chinese patients with familial amyotrophic lateral sclerosis
Creators: name: Xu, Guo-rong
name: Hu, Wei
name: Zhan, Ling-Ling
name: Wang, Chong
name: Xu, Liu-Qing
name: Lin, Min-Ting
name: Chen, Wan-Jin
name: Wang, Ning
name: Zhang, Qi-Jie
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Virology

description: Table S1. The primer sequences for TARDBP gene. (DOC 19Â kb)
Multitasking Emotion Recognition on Facial Expressions Using Window-Based Convolutional Neural Network
Creators: name: Isiaka, Fatima
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 460201
subject: Artificial life and complex adaptive systems
classificationCode: 460202
subject: Autonomous agents and multiagent systems
classificationCode: 460205
subject: Intelligent robotics
classificationCode: 460207
subject: Modelling and simulation
classificationCode: 460802
subject: Affective computing
classificationCode: 460806
subject: Human-computer interaction

description: Research has investigated that one doesn’t need words for a person to determine what is going on in a person’s face, the facial expression is an exact picture of a person’s mind. It is termed as an integral part of what we express in terms of emotion and a natural medium to communicate the most basic intentions. The world of human-machine interaction involves understanding and replicating the machine as a human and while the machine is learning human behaviour, it can also emulate patterns by training the Artificial intelligence (AI) to comprehend emotion that can take the concept of human-machine interactions to a higher level. This paper focuses on using a Convolutional Neural Network (CNN) as a multitasking engine to detect a person’s face from a database of facial representations of people in different moods. The two controls are, to use an input image to detect the best possible match at the same time detect the corresponding facial expression of the person based on emotional precognition for five (5) different expressions. The result shows that there is less error in person detection (0.2%) than in emotion precognition (0.0%). This would encourage more performance optimisation on the model with other dynamic controls in facial muscle movement for human-machine interaction and emotion emulation.
ВЛИЯНИЕ ВЫСОКОЧАСТОТНЫХ КОЛЕБАНИЙ ЖИДКОСТИ НА ВЯЗКОЕ КАПЕЛЬНОЕ ВКЛЮЧЕНИЕ В ЯЧЕЙКЕ ХЕЛЕ-ШОУ
Creators: name: КАРПУНИН И.Э.
name: КОЗЛОВ В.Г.
name: КОЗЛОВ Н.В.
Publisher: name: Конвективные течения
Year: 2019
Subjects: КАПЕЛЬНОЕ ВКЛЮЧЕНИЕ
ВЯЗКАЯ ЖИДКОСТЬ
ПУЛЬСИРУЮЩЕЕ ТЕЧЕНИЕ
ЯЧЕЙКА ХЕЛЕ-ШОУ
НЕОДНОРОДНОЕ ПОЛЕ СКОРОСТИ
ОСРЕДНЕННЫЕ СИЛЫ
DROPLET INCLUSION
VISCOUS FLUID
PULSATING FLOW
HELE-SHAW CELL
INHOMOGENEOUS VELOCITY FIELD
AVERAGED FORCES

description: Разработана экспериментальная установка, предназначенная для изучения динамики вязкого капельного включения в тонком зазоре (в ячейке Хеле-Шоу) при высокочастотном осциллирующем обтекании маловязкой жидкостью. Рассматривается осесимметричная ячейка с круговой боковой границей, в которой заполняющая ячейку маловязкая жидкость совершает осесимметричные радиальные колебания. Установка предназначена для экспериментального моделирования поведения вязких жидкостных включений в пористых средах при высокочастотных колебаниях насыщающей пористую среду маловязкой жидкости. Разработана методика регистрации капельного включения и изучения его временной динамики. Обнаружено, что высокочастотные радиальные колебания маловязкой жидкости приводят к различным осредненным эффектам. Во-первых, при вибрациях вязкое капельное включение меняет свою форму растягивается в азимутальном направлении, во-вторых, при вибрациях свободное включение дрейфует к центру ячейки. Определяющим в обнаруженном вибрационном явлении является высокий контраст вязкостей жидкостей.
Supplementary Material for: Perioperative Hemodynamic Instability and Fluid Overload are Associated with Increasing Acute Kidney Injury Severity and Worse Outcome after Cardiac Surgery
Creators: name: Haase-Fielitz, A.
name: Haase, M.
name: Bellomo, R.
name: Calzavacca, C.
name: Spura, A.
name: Baraki, H.
name: Kutschka, I.
name: Albert, C.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Purpose: The study aimed to investigate patients' characteristics, fluid and hemodynamic management, and outcomes according to the severity of cardiac surgery-associated acute kidney injury (CSA-AKI). Methods: In a single-center, prospective cohort study, we enrolled 282 adult cardiac surgical patients. In a secondary analysis, we assessed preoperative patients' characteristics, physiological variables, and medication for intra- and postoperative fluid and hemodynamic management and outcomes according to CSA-AKI stages by the Renal risk, Injury, Failure, Loss, End-stage renal disease (RIFLE) classification. Variables of fluid and hemodynamic management were further assessed with regard to the need for postoperative renal replacement therapy (RRT) and in-hospital mortality by the area under the curve for the receiver operating characteristic (AUC-ROC) and multivariate regression analysis. Results: Patients with worsening RIFLE stage, were significantly older, had lower estimated glomerular filtration rate and higher body mass index, more peripheral vascular and chronic obstructive pulmonary disease, atrial fibrillation, and prolonged duration of cardiopulmonary bypass (all p < 0.01). Patients with more severe AKI stage stayed longer in the intensive care and hospital, had higher in-hospital mortality, and requirement for RRT (all p < 0.001). Also, with worsening RIFLE stage, patients had lower intraoperative mean arterial pressure (MAP); p = 0.047, despite higher doses of norepinephrine (p < 0.001). The intraoperative MAP showed the best discriminatory ability (AUC-ROC: >0.8) for and was independently associated with RRT and in-hospital mortality. Moreover, with increasing AKI severity, patients received significantly more fluid infusion, and required higher dose of furosemide; nonetheless, they had increased postoperative fluid balance. Conclusions: In this cohort, reduced MAP and increased fluid balance were independently associated with increased mortality and need for RRT after cardiac surgery.
ВИБРАЦИОННАЯ ДИНАМИКА ДВУХЖИДКОСТНОЙ СИСТЕМЫ ПРИ ВРАЩЕНИИ
Creators: name: КАРПУНИН И.Э.
name: КОЗЛОВ Н.В.
Publisher: name: Конвективные течения
Year: 2019
Subjects: ВРАЩЕНИЕ
ВИБРАЦИИ
ДВУХЖИДКОСТНАЯ СИСТЕМА
ROTATION
VIBRATION
TWO-LIQUID SYSTEM

description: Экспериментально изучается влияние поступательных вибраций большой амплитуды на динамику двух несмешивающихся жидкостей, помещенных во вращающуюся горизонтальную цилиндрическую полость. Эксперименты проводятся при высокой скорости вращения, когда под действием центробежной силы легкая фаза располагается вблизи оси вращения. При этом частота вибраций близка к частоте вращения полости, а направление перпендикулярно оси вращения. Показано, что при совпадении частот вибрации изменяют конфигурацию центробежного поля. В результате столб легкой фазы смещается стационарно во вращающейся системе отсчета.
MOESM1 of Engineering CRISPR interference system in Klebsiella pneumoniae for attenuating lactic acid synthesis
Creators: name: Wang, Jingxuan
name: Zhao, Peng
name: Li, Ying
name: Xu, Lida
name: Tian, Pingfang
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Information Systems not elsewhere classified

description: Additional file 1: Fig. S1. Conserved lactic acid pathways in diverse species.
ВЛИЯНИЕ ИНЕРЦИОННЫХ КОЛЕБАНИЙ ЖИДКОСТИ НА АЗИМУТАЛЬНОЕ ТЕЧЕНИЕ В НЕРАВНОМЕРНО ВРАЩАЮЩЕМСЯ ЦИЛИНДРЕ
Creators: name: СУББОТИН С.В.
name: КРОПАЧЕВА А. С.
Publisher: name: Конвективные течения
Year: 2019
Subjects: ВРАЩЕНИЕ
ЛИБРАЦИИ
ИНЕРЦИОННЫЕ МОДЫ
ОСРЕДНЕННОЕ АЗИМУТАЛЬНОЕ ТЕЧЕНИЕ
ROTATION
LIBRATIONS
INERTIAL MODES
ZONAL FLOW

description: Экспериментально исследуется движение жидкости в цилиндрической полости, скорость вращения которой периодически изменяется (либрации). Либрации приводят к возникновению осредненного азимутального течения. Обнаружено, что профиль угловой скорости жидкости сильно зависит от частоты изменения скорости кюветы. В области частот, где инерционные колебания отсутствуют, генерируется отстающее течение, двумерность которого нарушается в углах вблизи торцов полости. Наличие инерционных колебаний сильно модифицирует азимутальное течение. Обнаружено, что около боковой стенки цилиндра возникают чередующиеся области отстающего и опережающего дифференциального вращения жидкости. Положение последних зависит от конкретного режима инерционных колебаний.
Systematic Support for Continuous Optimization of Lean-Based Manufacturing Systems
Creators: name: Yilmaz Uygun
Publisher: name: figshare
Year: 2017
Subjects: subject: 91005 Manufacturing Management
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 91006 Manufacturing Processes and Technologies (excl. Textiles)
subject: 91099 Manufacturing Engineering not elsewhere classified

description: Due to the organizational complexity that goes along with the introduction and application of a lean production system, companies cannot lift the full potential of lean production. Companies are missing tools that support in an automatic manner the development of lean production systems so that their full potential can be exploited. In this paper a tool in the form of an optimization system for lean production systems is presented that allows a comprehensive analysis of the current state of the application of lean methods and the proposal of relevant suggestions taking into consideration the diverse interrelations in the network of interdependent lean methods.
MOESM2 of Engineering CRISPR interference system in Klebsiella pneumoniae for attenuating lactic acid synthesis
Creators: name: Wang, Jingxuan
name: Zhao, Peng
name: Li, Ying
name: Xu, Lida
name: Tian, Pingfang
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2: Fig. S2. Schematic diagram of CRISPRi vectors and PuuC expression vector.
The Principle of Least Sensing: A Privacy-Friendly Sensing Paradigm for Urban Big Data Analytics
Creators: name: Wang, Leye
Publisher: name: arXiv
Year: 2022
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: With the worldwide emergence of data protection regulations, how to conduct law-regulated big data analytics becomes a challenging and fundamental problem. This article introduces the principle of least sensing, a promising sensing paradigm toward law-regulated big data analytics.
MOESM3 of Engineering CRISPR interference system in Klebsiella pneumoniae for attenuating lactic acid synthesis
Creators: name: Wang, Jingxuan
name: Zhao, Peng
name: Li, Ying
name: Xu, Lida
name: Tian, Pingfang
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Additional file 3: Table S1. Strains and vectors used in this study.
О ВЛИЯНИИ ДИФФЕРЕНЦИАЛЬНОГО ВРАЩЕНИЯ ЯДРА, КОЛЕБЛЮЩЕГОСЯ ВО ВРАЩАЮЩЕЙСЯ СФЕРИЧЕСКОЙ ПОЛОСТИ, НА УСТОЙЧИВОСТЬ ОСРЕДНЕННОГО ТЕЧЕНИЯ
Creators: name: КОЗЛОВ В.Г.
name: СУББОТИН С.В.
Publisher: name: Конвективные течения
Year: 2019
Subjects: ДИФФЕРЕНЦИАЛЬНОЕ ВРАЩЕНИЕ
КОЛЕБАНИЯ
ОСРЕДНЕННОЕ ТЕЧЕНИЕ
СДВИГОВАЯ НЕУСТОЙЧИВОСТЬ
ROTATION
OSCILLATIONS
STEADY FLOW
INSTABILITY
ROSSBY WAVES

description: Проводится сравнительный анализ надкритических течений, возбуждаемых колеблющимся ядром во вращающейся сферической полости с жидкостью. Рассматриваются две ситуации: когда ядро свободно и совершает дифференциальное вращение, и когда дифференциальное вращение ядра отсутствует. В обоих случаях колебания приводят к возникновению осредненного азимутального течения, в профиле которого наблюдается несколько точек перегиба. Повышение амплитуды колебаний приводит к потере устойчивости осесимметричного течения. При этом в надкритической области наблюдается серия пороговых переходов, связанных со сдвиговой неустойчивостью осредненного течения. Неустойчивость проявляется в развитии азимутальнопериодической системы вытянутых вдоль оси вихрей; различные моды отличаются азимутальной длиной волны, расположением вихрей (расстоянием от оси вращения) и азимутальной скоростью дрейфа системы относительно полости. Показано, что независимо от наличия дифференциального вращения ярда сценарии смены режимов надкритического течения остаются одинаковыми. В то же время критические значения числа Рейнольдса для неустойчивости одного типа различны.
ВИБРАЦИОННАЯ ДИНАМИКА НЕОСЕСИММЕТРИЧНОГО ТЕЛА В ЖИДКОСТИ ПРИ ПОСТУПАТЕЛЬНЫХ ВИБРАЦИЯХ
Creators: name: ЩИПИЦЫН В.Д.
name: ЛЕБЕДЕВА Г.М.
name: МАВЛЮТОВА Ю.Р.
Publisher: name: Конвективные течения
Year: 2019
Subjects: ЭЛЛИПТИЧЕСКИЙ ЦИЛИНДР
ВЯЗКАЯ ЖИДКОСТЬ
ВИБРАЦИИ
ГИДРОДИНАМИЧЕСКОЕ ВЗАИМОДЕЙСТВИЕ
ПОДЪЕМНАЯ СИЛА
ELLIPTICAL CYLINDER
VISCOUS LIQUID
VIBRATIONS
HYDRODYNAMIC INTERACTION
LIFT FORCE

description: Экспериментально исследуется поведение неосесимметричного цилиндра в заполненном вязкой несжимаемой жидкостью прямоугольном контейнере, совершающем поступательные гармонические колебания. В ходе экспериментов варьируются частота и амплитуда вибраций, вязкость жидкости. Эллиптические цилиндры имеют плотность как больше, так и меньше плотности жидкости (легкие и тяжелые тела). При варьировании вибрационного воздействия изучены характерные пороговые переходы тела близи горизонтальных границ полости (легкого вблизи потолка, тяжелого вблизи дна полости). С помощью скоростной видеосъемки процесса получены траектории осциллирующего движения неосесимметричного тела относительно полости.
Additional file 10: of Sorafenib versus Transarterial chemoembolization for advanced-stage hepatocellular carcinoma: a cost-effectiveness analysis
Creators: name: Chen, Shuling
name: Peng, Zhenwei
name: Wei, Mengchao
name: Liu, Weifeng
name: Dai, Zihao
name: Wang, Haibo
name: Mei, Jie
name: Cheong, Mingfong
name: Zhang, Hanmei
name: Kuang, Ming
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Table S9. References used to derive monthly mortality of advanced HCC patients with decompensated cirrhosis. (DOCX 12 kb)
ПОДЪЕМНАЯ СИЛА, ДЕЙСТВУЮЩАЯ НА ТЕЛО ВБЛИЗИ КОЛЕБЛЮЩЕЙСЯ ГРАНИЦЫ. РОЛЬ БЕЗРАЗМЕРНОЙ ЧАСТОТЫ
Creators: name: ВЛАСОВА О.А.
name: КАРПУНИН И.Э.
name: СОЛОМЕННИКОВ М.Н.
name: ВИВИАНИ А.
Publisher: name: Конвективные течения
Year: 2019
Subjects: ВРАЩЕНИЕ
ВЯЗКАЯ ЖИДКОСТЬ
ПОДЪЕМНАЯ СИЛА
ЦИЛИНДР
ROTATION
VISCOUS FLUID
LIFT FORCE
CYLINDER

description: Экспериментально исследуется динамика цилиндрического тела в горизонтальной цилиндрической полости с жидкостью, совершающей модулированное вращение. Периодическое изменение (модуляция) скорости вращения полости приводит к возникновению азимутальных колебаний тела в равномерно вращающейся системе отсчета за счет вязкого взаимодействия с границей полости. Показано, что на колеблющееся тело в центрифугированном состоянии действует осредненная сила отталкивания от границы полости. Подъемная сила измерена методом подвеса тела в центробежном поле в широком диапазоне безразмерных частот. Показано, что сила проявляется на расстоянии, сравнимом с толщиной динамических пограничных слоев.
ЭКСПЕРИМЕНТАЛЬНОЕ ИЗУЧЕНИЕ УСТОЙЧИВОСТИ ГРАНИЦЫ РАЗДЕЛА ЖИДКОСТИ И СЫПУЧЕЙ СРЕДЫ В НЕРАВНОМЕРНО ВРАЩАЮЩЕМСЯ ГОРИЗОНТАЛЬНОМ ЦИЛИНДРЕ
Creators: name: ПОЛЕЖАЕВ Д. А.
Publisher: name: Конвективные течения
Year: 2019
Subjects: ЖИДКОСТЬ
СЫПУЧАЯ СРЕДА
ВРАЩЕНИЕ
МОДУЛЯЦИЯ СКОРОСТИ ВРАЩЕНИЯ
РЕЛЬЕФ
УСТОЙЧИВОСТЬ
LIQUID
GRANULAR MEDIUM
ROTATION
MODULATION OF ROTATION RATE
RELIEF
STABILITY

description: Изучается устойчивость осесимметричной границы раздела между жидкостью и сыпучей средой во вращающемся горизонтальном цилиндре при модуляции скорости вращения. Внимание уделяется случаю, когда угловая скорость вращения меньше циклической частоты колебаний. Обнаружено, что межфазная граница неустойчива к возникновению рельефа в виде регулярных холмов. В начальной фазе развития неустойчивости пространственный период рельефа определяется толщиной вязкого слоя Стокса вблизи песчаной подложки, что позволяет предположить, что возникновение рельефа является следствием развития в жидкости квазистационарной неустойчивости слоя Стокса.
ЭКСПЕРИМЕНТАЛЬНОЕ ИЗУЧЕНИЕ РЕЛЬЕФА НА ПОВЕРХНОСТИ СЫПУЧЕЙ СРЕДЫ В НЕРАВНОМЕРНО ВРАЩАЮЩЕМСЯ ГОРИЗОНТАЛЬНОМ ЦИЛИНДРЕ С ЖИДКОСТЬЮ
Creators: name: ВЛАСОВА К.А.
name: ДЬЯКОВА В.В.
name: ПОЛЕЖАЕВ Д.А.
Publisher: name: Конвективные течения
Year: 2019
Subjects: ЖИДКОСТЬ
СЫПУЧАЯ СРЕДА
РЕЛЬЕФ
ЛИБРАЦИИ
FLUID
GRANULAR MEDIUM
BED FORMS
LIBRATION

description: Изучается квазистационарный регулярный рельеф на границе раздела между жидкостью и сыпучей средой в неравномерно вращающемся (либрирующем) горизонтальном цилиндре. Проведено систематическое экспериментальное исследование пространственного периода и высоты регулярного рельефа в зависимости от частоты и амплитуды колебаний жидкости, диаметра частиц сыпучей среды и ее количества. Обнаружено, что пространственный период рельефа полностью определяется амплитудой колебаний жидкости. Исключение составляет случай, когда толщина слоя сыпучей среды недостаточна для формирования рельефа нужного размера. Управляющим параметром для определения относительной высоты рельефа является критерий мобильности.
НЕОСЕСИММЕТРИЧНОЕ ТЕЧЕНИЕ, ВОЗБУЖДАЕМОЕ КОЛЕБАНИЯМИ ЖИДКОСТИ ВО ВРАЩАЮЩЕМСЯ ЦИЛИНДРЕ С НАКЛОННЫМИ ТОРЦАМИ
Creators: name: СУББОТИН С.В.
name: ШИРЯЕВА М. А.
Publisher: name: Конвективные течения
Year: 2019
Subjects: ВРАЩЕНИЕ
ЛИБРАЦИИ
НЕОСЕСИММЕТРИЧНЫЕ ИНЕРЦИОННЫЕ КОЛЕБАНИЯ ЖИДКОСТИ
ОСРЕДНЕННОЕ ТЕЧЕНИЕ
ROTATION
LIBRATIONS
NON-AXISYMMETRIC INERTIAL MODES
STEADY FLOW

description: Экспериментально исследуется течение в неравномерно вращающейся (либрирующей) цилиндрической полости, торцы которой наклонены относительно оси вращения. Периодические изменения скорости вращения приводят к возникновению интенсивных инерционных колебаний жидкости. Благодаря азимутальной неоднородности геометрии торцов инерционные колебания происходят неосесимметричным образом. В результате нелинейного отклика вдоль боковой границы полости возникает неосесимметричное осредненное течение. Обнаружено, что изменение режима пульсационного движения жидкости приводит к трансформации структуры осредненного течения.
Towards Understanding Analytics in Software Startups
Creators: name: Rafiq, Usman
Publisher: name: arXiv
Year: 2022
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences
subject: D.2; K.6.3

description: Analytics plays a crucial role in the data-informed decision-making processes of modern businesses. Unlike established software companies, software startups are not seen utilizing the potential of analytics even though a startup process should be primarily data-driven. There has been little understanding in the literature about analytics for software startups. This study set out to address the knowledge gap by exploring how analytics is understood in the context of software startups. To this end, we collected the qualitative data of three analytics platforms that are mostly used by startups from multiple sources. We covered platform documentation as well as experience reports of the software startups using these platforms. The data was analyzed using content analysis techniques. Four high-level concepts were identified that encapsulate the real understanding of software startups on analytics, including instrumentation of analytics, experimentation, diagnostic analysis, and getting insights. The first concept describes how startups set up analytics and the latter three illustrate the usage scenarios of analytics. This study is the first step toward understanding analytics in the software startup context. The identified concepts can guide further investigation of analytics in this context. It also provides some insights for software startups to set up analytics for data-informed decisions. Given the limitation of the data used in the study, the immediate next step is to ground as well as validate the acquired understanding using the primary data, by directly interacting with software startups.
description: 8 pages, 2 figures, accepted for presentation at 5th International Workshop on Software-intensive Business: Towards Sustainable Software Business, Pittsburgh, PA, USA
MOESM4 of Engineering CRISPR interference system in Klebsiella pneumoniae for attenuating lactic acid synthesis
Creators: name: Wang, Jingxuan
name: Zhao, Peng
name: Li, Ying
name: Xu, Lida
name: Tian, Pingfang
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Information Systems not elsewhere classified
subject: Computational Biology

description: Additional file 4: Table S2. Primers for engineering CRISPRi vectors.
Synthesis of marine alkaloids leucettamines B and C by β-lactam ring rearrangement
Creators: name: Dražić, Tonko
name: Krešimir Molčanov
name: Jurin, Mladenka
name: Roje, Marin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology

description: A new method for the synthesis of marine alkaloids leucettamines B and C from Leucetta sp. sponges is described. The key step is the base-promoted rearrangement of β-lactam into imidazolone ring. Leucettamines B and C as well as their N-benzoyl derivatives were obtained in high yields. Single-crystal structures of both leucettamines B and C were determined by X-ray diffraction confirming Z-configuration of double bond at 4-position of imidazolone.
Facile synthesis of naturally occurring nor-lignans (±)-Machicendiol and its analogs
Creators: name: Kishor R. More
name: R. S. Mali
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Computational Biology

description: A facile synthesis of naturally occurring (±)-machicendiol and its analogs has been accomplished in moderate to good yield from 2-aryl-5-formly-7-methoxy-benzofurans through two simple, efficient approaches involving the application of Reformatsky reaction and Claisen condensation.
Markers of vulnerability for emotion dysregulation disorders
Creators: name: Nemitz, Camille Marie
Publisher: name: Université de Genève
Year: 2021
Subjects: info:eu-repo/classification/ddc/616.89
Emotion regulation disorders
Early intervention
Neurobiological markers
Dimensional approach

description: In the context of prevention in mental health, a rising concern, recent advances in psychiatric research advocate for the development of early intervention for adolescents. Indeed, adolescence is a period of high vulnerability to psychiatric disorders, associated with specific brain development's steps. The model of clinical staging for psychiatric disorders suggests that early interventions should target transdiagnostic vulnerability markers, however such markers are difficult to uncover. Nevertheless, following a dimensional approach, emotion dysregulation could represent an important marker for different disorders, particularly in affective and impulse- control disorders. We will review here the arguments linking emotion dysregulation, brain development and the emergence of psychiatric disorders, as well as the various biological markers associated, following with the therapeutic interventions that could target these markers.