cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Un modèle théorique de la genèse du trouble d'anorexie mentale.
Creators: name: Joubert, Natacha.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Psychology, Clinical.

description: Cette these theorique propose une conception cognitive de la genese de l'anorexie mentale qui, contrairement aux principaux modeles etiologiques du trouble, permet d'integrer de facon explicite le jeu des facteurs internes et externes. Il y est question notamment de la variabilite dans le rapport entre les fonctions cognitives d'assimilation et d'accommodation, laquelle est posee comme etant attribuable (1) a ces propensions individuelles de nature innee, (2) a des propensions contextuelles dues aux pressions exercees par le milieu et (3) a des propensions developpementales qui agiraient de maniere dachronique sur divers aspects du developpement cognitif des individus. Ces propensions influeraient sur la mise en place des schemes cognitifs en general et sur celle de schemes de soi en particulier, laquelle, au moment du passage au stade operatoire formele, engendrerait un phenomene que nous avons appele de permanence du sujet. Ce phenomene entrai nerait chez les individus la cristallisation d'une representation de soi en tant que sujet detenant le controle parmi un champ de controles possibles. D'autre part, ces propensions seraient responsables, chez les anorexiques, de la misse en place de schemes de soi pathogenes qui, etant donne la conjoncture qui prevaut au moment de leur arrivee a l'adolescence, se caracteriserait par la cristallisation d'une representation de soi en tant que sujet qui ne concoit le controle qu'a travers le controle du corps. C'est ainsi qu'elles en viendraient a ne generaliser le controle qu'a des objets ou des situations qui se rattachent au controle du corps (v.g. exercices physiques excessifs, diete alimentaire, abus de laxatifs), d'ou l'emergence de schemes de soi anorexiques. Ne parvenant plus a se definir autrement que par rapport au controle du corps, perdre du poids representerait pour elles la seule facon d'etre.
The increase of childhood obesity in a limited sample of Canadian children between 1979 and 1998.
Creators: name: Grenier, Mark.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Health Sciences, Public Health.

description: Overweight and obesity are important public health concerns associated with a variety of negative physiological and psychological consequences in children, youth as well as in adults. The objective of this study was to evaluate the increase in childhood overweight and obesity in a Canadian sample of 7 to 12 year olds between 1979 and 1998 using the BMI as the indicator of obesity. Analyses of variance were performed on the data between the different study cohorts. The 85$\rm\sp{th}$ and 95$\rm\sp{th}$ age and gender specific percentile of BMI of the 1979 CAHPERD study respectively defined overweight and obesity cut-off points. Results support previous studies and clearly show a significant increase in the prevalence of overweight and obesity in today's children. They also show a higher increase of overweight and obesity in girls than in boys. Since childhood obesity is an increasingly important predictor of adult obesity and obesity in adults is associated with a number of health consequences, regular screening of children for overweight and obesity should be put in place and preventive measures taken when children are at risk. (Abstract shortened by UMI.)
Proton radiography of a laser-driven implosion
Creators: name: MacKinnon, A. J.
name: Patel, P. K.
name: Borghesi, M.
name: Clarke, R. C.
name: Freeman, R. R.
name: Habara, H.
name: Hatchett, S. P.
name: Hey, D.
name: Hicks, Damien
name: Kar, S.
name: Key, M. H.
name: King, J. A.
name: Lancaster, K.
name: Neely, D.
name: Nikkro, A.
name: Norreys, P. A.
name: Notley, M. M.
name: Phillips, T. W.
name: Romagnani, L.
name: Snavely, R. A.
name: Stephens, R. B.
name: Town, R. P J
Publisher: name: Swinburne
Year: 2024

description: Protons accelerated by a picosecond laser pulse have been used to radiograph a 500 mu m diameter capsule, imploded with 300 J of laser light in 6 symmetrically incident beams of wavelength 1.054 mu m and pulse length 1 ns. Point projection proton backlighting was used to characterize the density gradients at discrete times through the implosion. Asymmetries were diagnosed both during the early and stagnation stages of the implosion. Comparison with analytic scattering theory and simple Monte Carlo simulations were consistent with a 3 +/- 1 g/cm(3) core with diameter 85 +/- 10 mu m. Scaling simulations show that protons > 50 MeV are required to diagnose asymmetry in ignition scale conditions.
Supplementary document for Giant enhancement of silicon plasmonic SWIR photodetection using nanoscale self-organised metallic films - 4472625.pdf
Creators: name: Frydendahl, Christian
name: Grajower, Meir
name: Bar-David, Jonathan
name: Zektzer, Roy
name: Mazurski, Noa
name: Shappir, Joseph
name: Levy, Uriel
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Photodetectors, Optical Sensors and Solar Cells

description: Supplementary materials
Genetic and epidemiological analysis of norovirus from children with gastroenteritis in Botswana, 2013–2015
Creators: name: Makhaola, Kgomotso
name: Moyo, Sikhulile
name: Lechiile, Kwana
name: Goldfarb, David M
name: Kebaabetswe, Lemme P
Publisher: name: BioMed Central
Year: 2018

description: Background: Norovirus is a leading cause of viral gastroenteritis worldwide with a peak of disease seen in children. The epidemiological analysis regarding the virus strains in Africa is limited. The first report of norovirus in Botswana was in 2010 and currently, the prevalence and circulating genotypes of norovirus are unknown, as the country has no systems to report the norovirus cases. This study investigated the prevalence, patterns and molecular characteristics of norovirus infections among children ≤5 years of age admitted with acute gastroenteritis at four hospitals in Botswana. Methods: A total of 484 faecal samples were collected from children who were admitted with acute gastroenteritis during the rotavirus vaccine impact survey between July 2013 and December 2015. Norovirus was detected using real-time RT-PCR. Positive samples were genotyped using conventional RT-PCR followed by partial sequencing of the capsid and RdRp genes. Norovirus strains were determined by nucleotide sequence analysis using the online Norovirus Genotyping Tool Version 1.0, and confirmed using maximum likelihood tree construction as implemented in MEGA 6.0. Results: The prevalence of norovirus was 9.3% (95% CI 6.7–11.9). The genotype diversity was dominated by the GII.4 strain at 69.7%. This was followed by GII.2, GII.12 each at 9.1%, GI.9 at 6.6% and GII.6, GII.10 each at 3.0%. The most common combined RdRp/Capsid genotype was the GII.Pe/GII.4 Sydney 2012. Norovirus was detected during most part of the year; however, there was a preponderance of cases in the wet season (December to March). Conclusion: The study showed a possible decline of norovirus infections in the last 10 years since the first report. An upward trend seen between 2013 and 2015 may be attributable to the success of rotavirus vaccine introductions in 2012. Knowledge of circulating genotypes, seasonal trends and overall prevalence is critical for prevention programming and possible future vaccine design implications.
Supplementary document for Giant enhancement of silicon plasmonic SWIR photodetection using nanoscale self-organised metallic films - 4472625.pdf
Creators: name: Frydendahl, Christian
name: Grajower, Meir
name: Bar-David, Jonathan
name: Zektzer, Roy
name: Mazurski, Noa
name: Shappir, Joseph
name: Levy, Uriel
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Photodetectors, Optical Sensors and Solar Cells

description: Supplementary materials
Evaluation of properties of lignin derived from local biomass using low temperature transition mixture and its extraction process
Creators: name: Wong, Jung Lin
Publisher: name: Swinburne
Year: 2024

description: The current study applied sucrose/malic acid/water (SMAW) low transition temperature mixture (LTTM) for the pretreatment of oil palm empty fruit bunch, oil palm trunk, oil palm mesocarp fibre, oil palm kernel shell, rice husk, coconut husk, coconut shell, and cocoa kernel shell. The outcomes from this study represented the culmination of extensive experimentation and analysis and have the potential to offer valuable insights into lignin recovery and pretreatment methodologies for diverse lignocellulosic feedstocks. The implications of these findings can potentially be applied in the scale-up implementation of the SMAW LTTM for multi-feedstock biomass pretreatment.
title: Flourishing or floundering? Exploring Ukrainian elementary schoolteacher understandings of their professional experience
Creators: name: Pidzamecky, Ulana Plawuszczak
Publisher: name: University of Glasgow
Year: 2024

description: This empirical study investigated Ukrainian elementary (in the UK, known as primary) schoolteacher perceptions of their professional flourishing within the current education environment in Ukraine. It involved 12 teachers from different parts of the country and explored the relationship between professional and personal flourishing. In addition, the research attended to the contexts of state and society within conditions of ongoing neoliberal education reform since Ukraine declared independence in 1991. Teacher opinions were also solicited about the relationship between professional flourishing and continuous professional development (CPD) in this dynamic climate. Their views were elicited as well about a preferred educational future for the evolving democracy of Ukraine under the impact of the worldwide coronavirus pandemic and the Russian invasion in 2022. The study took a qualitative approach and employed narrative inquiry using visually based data collection techniques (‘river of experience’ and autophotography/photo elicitation), along with semi-structured focused group discussions and individual interviews. It responds to a gap in the broader literature about drivers of work engagement (disengagement) and meaningfulness (Long, 2014). Additionally, the discourse remains scant in the studies of post-communist/post-totalitarian education systems and is underrepresented in the literature (Oleksiyenko, 2016). Findings revealed that three fundamental confluences contributed to the teacher-participants’ journeys of professional flourishing, individually and collectively: perseverance: managing personal and practitioner difficulties, field challenges, and societal crises; innovation: embracing and creating new techniques and technologies; and identity: transitioning from a centralized to a capitalist economy and balancing the new forces of neoliberalism, Europeanism, and globalization while educating children for Ukraine. The implications of these findings are discussed, and topics for further research are proposed.
Harmonised VOC emission classes for construction products
Creators: name: Reihlen, Antonia
name: Jepsen, Dirk
Publisher: name: Umweltbundesamt
Year: 2021
Subjects: subject: construction products
subject: European harmonisation
subject: EU-LCI
subject: Construction products Regulation
subject: Chemicals
subject: Economy | Consumption
subject: Health

description: Die vorliegende Dokumentation fasst die Vorträge und Diskussionen einer vom Umweltbundesamt im April 2021 organisierten internationalen Online-Konferenz zu Emissionsklassen für flüchtige organische Verbindungen (VOC) in Bauprodukten zusammen. Bauprodukte sind eine wichtige Quelle für VOC-Emissionen in die Innenraumluft. Im Rahmen der Bauproduktenverordnung wurde ein Kammertest genormt, damit die Ergebnisse von Messungen der VOC-Emissionen aus Bauprodukten harmonisierter erhoben und dokumentiert werden. Wenn Produktnormen Angaben über VOC-Emissionen fordern, müssen diese als Teil der Leistungserklärung angegeben werden. Um den Produktnutzer*innen verständliche Informationen zur Verfügung zu stellen, wurde von einigen Mitgliedstaaten ein Klassensystem vorgeschlagen, um die Leistung eines Produktes bzgl. der VOC-Emissionen in fünf Stufen zu unterteilen. Dem Vorschlag zufolge werden vier Leistungsmerkmale bewertet, um ein Produkt einer VOC-Emissionsklasse zuzuordnen. Die Resonanz auf diesen Vorschlag war insgesamt positiv. Quelle: Forschungsbericht
description: The current documentation summarises the presentations and discussions of an international online conference organised by the German Environment Agency in April 2021 on emission classes for volatile organic compounds (VOCs) in construction products. Construction products are an important source of VOC emissions into indoor air. A chamber test was standardised under the Construction Products Regulation to enable harmonised measurement results of VOC emissions from construction products. If required by the product standards, the VOC emissions must be reported as part of the performance declaration. To provide understandable information to the product users, a class system was proposed by some of the Member States to differentiate the VOC emission performance into five levels. According to the proposal, four performance characteristics are evaluated to allocate a product to a VOC emission class. The overall feedback to the proposal was positive. Quelle: Forschungsbericht
description: This documentation summarises the presentations and the discussions of the international online conference "Limiting Health Impacts of Construction Products regarding Volatile Organic Compounds" organised by the German Environment Agency in April 2021.The conference presented the current status of harmonisation activities on the topic of construction product emissions as well as a concrete proposal for harmonised emission classes for volatile organic compounds. The publication is addressed to national authorities, universities, research institutes and non-governmental organisations dealing with the topic of health protection and emissions from construction products.
Einsatz von KIs für Studierende BIB&BIM
Creators: name: Berdyszak, Marian
name: Bleich, Annika
name: Block, Vanessa
name: Gaßner, Michelle
name: Greil, Elisabeth
name: Köbele, Carmen
name: Kuck, Hendrik
name: Kuhn, Tom
name: Le, Mira
name: Salamone, Giulia
name: Zettisch, Viktoria
Publisher: name: Zenodo
Year: 2024

description: Ergebnisse des Projektes "Sinnvoller Einsatz von Großen Sprachmodellen in Studium und Lehre" an der Hochschule Hannover von den Studierenden des Studiengangs Informationsmanagement berufsbegleitend. Das "CheatSheet" und das Video enthalten Hinweise und Anregungen zur sinnvollen Nutzung von KI im Studium Informationsmanagement.
"L 'Homme africain" et ses masques Anthropologie psychologique de la personne, de la psychiatrie coloniale à l'École postcoloniale de l'hôpital Fann-Dakar au Sénégal
Creators: name: Foucault, Patrick
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Anthropology, Cultural.
subject: Health Sciences, Mental Health.
subject: Sociology, General.

description: Entre l'époque coloniale et la décolonisation se développa un dialogue fécond, mais inégal entre les deux disciplines que sont la psychologie et l'anthropologie (grâce à Kraepelin, Freud, Mead, Benedict, Linton et Kardiner, notamment). Une nouvelle discipline naquit alors, celle de la psychologie anthropologique, qui usa de sa scientificité pour développer un discours sur l'homme. Homme parfois ramené à une psychologie aux fondements évolutionnistes (au nègre, à l'homme de la horde), d'autre fois incompréhensible sans l'étude de sa culture (à une personnalité de base), mais, aussi compris comme totalité (l'homme total). Ainsi, grâce à l'École française de sociologie et d'anthropologie (Durkheim, Bastide, Devereux, Levi-Strauss et particulièrement Marcel Mauss), s'instaura une manière nouvelle d'appréhender l'homme, un autre regard à poser sur lui. Regard égalisant davantage les disciplines qui l'étudient. Regard désirant le saisir dans sa totalité, voulant voir l'homme concret socialement institué, la personne telle qu'elle est vécue par le groupe. Du travail maussien sur l'Homme en général sembla émerger une réflexion historico-anthropologique sur la personne, particulière selon la culture où elle se trouve. Ainsi, Marcel Mauss donna naissance à l'anthropologie de la personne, qui saura intéresser bon nombre de ses étudiants et collègues (Dumont, Griaule, Meyerson, Leenhardt), et qui marquera aussi de nombreuses recherches postcoloniales, telles que celles menées à l'hôpital Fann de Dakar. Lieu où, au sortir de la colonisation sénégalaise, les chercheurs (Collomb, Zempleni, Ortigues, Sow) s'inspirèrent de la discipline anthropologico-psychologique pour penser l'Homme africain, et particulièrement, son fou. Ils tentèrent de décoloniser la psychiatrie par la réintégration du savoir et des pratiques traditionnelles. Ils voulurent de plus créer une psychiatrie capable de saisir le personnage africain pour ce qu'il est dans son milieu, l'idéalité symbolique qu'il représente. Un personnage masqué grâce à une triple relation aux ancêtres, à la communauté et a soi-même. Personnage total à l'image de ses pratiques thérapeutiques traditionnelles, incorporant sa culture et incorporé par celle-ci.
MAKTABGACHA TA'LIM TASHKILOTLARINI BOSHQARISHNING HOZIRGI HOLATI VA MUAMMOLARI
Creators: name: Gʻaniyeva, A.Z.
Publisher: name: Zenodo
Year: 2024

description: Mazkur maqolada innovatsion yondashuvlar asosida maktabgacha ta'lim tashkilotlarini boshqarishning hozirgi holati va muammolari hamda xodimlarning raqamli savodxonligini oshirish bosqichlari keltirilgan.
Prospects for the expansion of Eastern Orthodoxy in Canada
Creators: name: Somers, David
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Religion, General.

description: After a century of persistent linguistic, theological and cultural isolation, Eastern Orthodoxy is uniquely poised to expand beyond its ethnic-bound limits to take its place in Canadian mainstream Christianity in the twenty-first century, even while many foundations of institutional Christianity are being undermined. Several factors are at work to allow Eastern Orthodoxy to realize this favorable position. One is the strength of its unified doctrine, another is a current in postmodern North America moving to more orthodox expressions of Christianity. Another factor is an increased youthful immigration of Eastern Orthodox faithful which invigorates and validates the established segment of increasingly socially acculturated Eastern Orthodox Canadians. Parallel to those elements is the erosion of certain aspects of Roman Catholic and Protestant strongholds, opening the way to the consideration of alternatives outside those traditions. Protestant membership and attendance have continued to decline over the past several decades while Roman Catholicism is plagued with a tarnished image, largely over sex-related issues. The relatively unknown character of Eastern Orthodoxy provides a fresh outlook of a familiar Christian foundation through intensely Trinitarian doctrine manifested in part in the oriental mysticism of hesychasm and iconography, appealing to a general rising interest in things eastern. As never before, the recent simultaneous convergence of these multifarious factors allows for the prospect of expansion of Eastern Orthodoxy in Canada in the twenty-first century.
title: Übersicht zur Entwicklung der energiebedingten Emissionen und Brennstoffeinsätze in Deutschland 1990 - 2016
title: Entwicklung energiebedingter Emissionen und Brennstoffeinsätze
titleType: AlternativeTitle
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2018
Subjects: subject: Energiebedingte Emissionen
subject: Treibhausgasemission
subject: Luftschadstoff
subject: Freisetzung von Treibhausgasen
subject: Luftschadstoffausstoß
subject: Brennstoffeinsatz
subject: Klima | Energie
subject: Luft
subject: Climate | Energy
subject: Air

description: „Energiebedingte Emissionen“ sind Treibhausgase und Luftschadstoffe, die durch die Umwandlung von Energieträgern in elektrische und / oder thermische Energie (Strom- und Wärmeproduktion) freigesetzt werden. In dieser Veröffentlichung hat das ⁠UBA⁠ für die Jahre 1990 bis 2016 Grafiken und Tabellen zusammengestellt, die die energiebedingten Emissionen für Treibhausgase und ausgewählte Luftschadstoffe und die Menge der dafür eingesetzten Brennstoffe nach Sektoren aufgeschlüsselt darstellen.
Assessing segmental versus non-segmental features in the ventral nervous system of onychophorans (velvet worms)
Creators: name: Martin, Christine
name: Gross, Vladimir
name: Pflueger, Hans-Joachim
name: Stevenson, Paul A.
name: Mayer, Georg
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Segmentation
subject: Nerve cord
subject: Ganglia
subject: Arthropod
subject: Panarthropoda
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie

description: Background Due to their phylogenetic position as one of the closest arthropod relatives, studies of the organisation of the nervous system in onychophorans play a key role for understanding the evolution of body segmentation in arthropods. Previous studies revealed that, in contrast to the arthropods, segmentally repeated ganglia are not present within the onychophoran ventral nerve cords, suggesting that segmentation is either reduced or might be incomplete in the onychophoran ventral nervous system. Results To assess segmental versus non-segmental features in the ventral nervous system of onychophorans, we screened the nerve cords for various markers, including synapsin, serotonin, gamma-aminobutyric acid, RFamide, dopamine, tyramine and octopamine. In addition, we performed retrograde fills of serially repeated commissures and leg nerves to localise the position of neuronal somata supplying those. Our data revealed a mixture of segmental and non-segmental elements within the onychophoran nervous system. Conclusions We suggest that the segmental ganglia of arthropods evolved by a gradual condensation of subsets of neurons either in the arthropod or the arthropod-tardigrade lineage. These findings are in line with the hypothesis of gradual evolution of segmentation in panarthropods and thus contradict a loss of ancestral segmentation within the onychophoran lineage.
Supplementary document for Few-cycle lightwave-driven currents in a semiconductor at high repetition rate - 4473633.pdf
Creators: name: Langer, Fabian
name: Liu, Yen-Po
name: Ren, Zhe
name: Flodgren, Vidar
name: Guo, Chen
name: Vogelsang, Jan
name: Mikaelsson, Sara
name: Sytcevich, Ivan
name: Ahrens, Jan
name: L'Huillier, Anne
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Suplementary information
Claudin proteins and the regulation of epithelial proliferation and differentiation: A mutual correlation
Creators: name: Arabzadeh, Azadeh
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Biology, Molecular.
subject: Biology, Cell.

description: One mode of cell-cell adhesion between epithelial and endothelial cells is mediated by tight junctions (TJs), complex structures which serve two major roles: (1) they constitute a barrier to the passage of ions and small molecules through the paracellular space and (2) they restrict the movement of lipids and proteins between the apical and basolateral compartments of the plasma membrane. It is now widely recognized that the Claudin (Cldn) family of tetraspan membrane proteins is crucial for TJ assembly and barrier function. Although originally proposed as structural components of TJs, recent evidence implicate the signaling function of Cldns. Notably, a bilateral correlation between Cldns and signal transduction pathways regulating cell proliferation/differentiation is emerging; on one hand Cldns can undergo changes in response to altered proliferation-differentiation, and on the other hand changes in Cldns can result in proliferation and/or differentiation perturbations. Along this line, studies from our laboratory have confirmed that such connection exists. Using the mouse epidermis as a model system, we first reported that overexpression of endogenous Cldn6 in this tissue perturbs both the balance of other Cldn isoforms as well as the normal process of epidermal differentiation. To elucidate the mechanism behind this effect, we looked towards the Cldn6 C-terminal tail; a region that may interact with yet-unidentified molecules involved in transducing signals of epidermal differentiation. Therefore, deletion of the tail domain was assumed to lead us to Cldn6 signaling function; indeed expression of tail-ablated Cldn6 not only disrupted epidermal differentiation but also increased cell proliferation. Loss of epidermal homeostasis was apparently due to the loss of Cldn homeostasis. We were next curious to know whether the correlation of Cldns to proliferation-differentiation is of a reciprocal nature. Therefore, two well-known models of tissue injury response and chemical carcinogenesis were used, in order to induce proliferation-differentiation aberrancy. Examining various Cldns in both models indicated that in response to perturbed proliferation-differentiation Cldns undergo changes, further raising a two-sided regulatory function between Cldns and intracellular signaling pathways.
Supplementary document for Few-cycle lightwave-driven currents in a semiconductor at high repetition rate - 4473633.pdf
Creators: name: Langer, Fabian
name: Liu, Yen-Po
name: Ren, Zhe
name: Flodgren, Vidar
name: Guo, Chen
name: Vogelsang, Jan
name: Mikaelsson, Sara
name: Sytcevich, Ivan
name: Ahrens, Jan
name: L'Huillier, Anne
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Suplementary information
Sind kupferhaltige Antifouling-Anstriche ein Problem für unsere Gewässer?
Creators: name: Ahting, Maren
name: Feibicke, Michael
name: Nöh, Ingrid
name: Rissel, Ricarda
name: Schmidt, Ralf
name: Schwanemann, Torsten
name: Setzer, Sascha
Publisher: name: My University
Year: 2018
Subjects: subject: Wasser
subject: Sportboote
subject: Chemikalien
subject: Wasser

description: Sportboote tragen mit Antifouling-Anstrichen des Unterwasserrumpfes zu Chemikalieneinträgen in Gewässer bei. Erstmals konnten die Einträge von Kupfer und anderen Bioziden aus dieser Quelle abgeschätzt werden: Jährlich gelangen 70.5 t Kupfer, 20 t Zink und 9.5 t organische Biozide in deutsche Binnengewässer. Damit konnten 19 % der Kupfereinträge auf diese Anwendung zurückgeführt werden. Da Grenzwerte für Kupfer immer wieder überschritten werden, sollten Maßnahmen ergriffen werden, um die Einträge zu reduzieren und die Gewässer zu schützen. Quelle: https://www.umweltbundesamt.de
description: Sportboote tragen mit Antifouling-Anstrichen des Unterwasserrumpfes zu Chemikalieneinträgen in Gewässer bei. Erstmals konnten die Einträge von Kupfer und anderen Bioziden aus dieser Quelle abgeschätzt werden: Jährlich gelangen 70.5 t Kupfer, 20 t Zink und 9.5 t organische Biozide in deutsche Binnengewässer. Damit konnten 19 % der Kupfereinträge auf diese Anwendung zurückgeführt werden. Da Grenzwerte für Kupfer immer wieder überschritten werden, sollten Maßnahmen ergriffen werden, um die Einträge zu reduzieren und die Gewässer zu schützen.
A comparison of irritable bowel syndrome and Crohn's disease: Mechanisms underlying symptom processing and sickness impact.
Creators: name: Pigeon-Reesor, Helen.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Health Sciences, Public Health.

description: Previous research suggests an association between psychological dysfunction and Irritable Bowel Syndrome (IBS). We sought to confirm this relationship and examine the mechanisms by which psychosocial factors may amplify or maintain IBS complaints, and influence disability. One hundred and thirteen female participants, (45 IBS; 34 Crohn's; 34 healthy controls) were evaluated by psychological assessment which measured: symptom reporting, anxiety, depression, and impact of physical symptoms on daily activities. The assessment also evaluated the ways in which patients interpreted, understood and coped with unpleasant symptoms as well as the support and reactions from significant others to their symptoms. Subjects also participated in an experimental task designed to elicit physical sensations. Following the task, subjects were interviewed regarding cognitions and symptoms associated with the task. Results indicated that both patient groups had significantly greater physical and emotional symptomatology than healthy controls. The IBS patients were largely indistinguishable from the Crohn's patients, except that IBS patients were more likely to perceive their condition as more serious than Crohn's patients, and reported less personal control and responsibility in managing their symptoms. IBS patients also perceived far less social support from individuals close to them than did the Crohn's patients. Both IBS and Crohn's patients engaged in greater dysfunctional cognitive activity than did the controls during the experimental task. While anxiety, depression and coping attempts did not distinguish between patient groups, they were significantly associated with the amount of disability in daily activities regardless of diagnosis. These results suggest that the uncertain etiology of IBS may create additional sources of stress for the IBS patient. Consequently IBS patients may be more prone to misinterpret their IBS as a serious health threat and feel less able to control their symptoms. Furthermore, because of the uncertain etiology, the IBS patient may receive less support from significant others, thereby compounding stress and further taxing coping efforts. Our findings suggest that rather than a psychologic/psychiatric problem the IBS is better viewed as a medical problem within a biopsychosocial context. Psychosocial factors play a crucial role in the manifestation of disability regardless of the nature of the disease. However, the IBS is a unique medical problem in that the patient is placed at risk for stressors related to the uncertainty of the symptoms and the reactions of others.
Kinetics of the liquid phase oxidation of ethanol on a palladium-on-alumina catalyst.
Creators: name: Hsu, Shih-Hau.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1977
Subjects: subject: Engineering, Chemical.

description: The oxidation of ethyl alcohol has been studied in an aqueous phase containing sodium carbonate over the temperature range 25 to 45°C, using a stirred semibatch reactor with four baffles containing 0.5% Pd-A12O 3 catalyst pellets. The intrinsic kinetic equations were derived empirically using the rate measurements of a stirred slurry reactor in which finely crushed pellets were suspended. The oxidation rate was found to be first order with respect to dissolved oxygen concentration which varied from 3.5 to 18.5 mg/liter. Both the gas-liquid interface and the liquid-particle surface mass transfer resistances were evaluated and found to be negligible. The measured effectiveness factor for the pellets, which was estimated by the ratio of reaction rate of the pellet system to that of the powder system, could be brought into agreement with theory by using a tortuosity value of 2.9.
Leadership Style and Job Satisfaction: Their Impact on Non-Academic Staff's Turnover Intention in Self-Accrediting Universities in Malaysia
Creators: name: Gan, Evelyn
Publisher: name: Swinburne
Year: 2024

description: The importance of non-academic staff is increasing as their roles are expanding to handle the core functions of a university's operations. However, little research attention has been given to non-academic staff. This study specifically addresses these issues by examining the relationship between leadership style and non-academic staff's turnover intention, with job satisfaction as a mediator among 11 self-accrediting universities. This research is valuable to university policy makers to design more effective human resource policies and practices, with a focus on teamwork and development, management transparency, and promotional opportunities that can reduce turnover intention and consequently retain talent within the university.
“Vaccine safety and trust is my concern” : a qualitative exploration of lactating people's perspectives on COVID-19 vaccination in British Columbia
Creators: name: Senkyire, Ephraim
Publisher: name: University of British Columbia
Year: 2025

description: Lactating people experiencing SARS-CoV-2 infection encounter greater physical, emotional, and psychosocial challenges during the postpartum period compared to the general population. Despite the importance of COVID-19 vaccination globally, campaigns aimed at vaccinating at-risk populations, including lactating people, have faced challenges, leading to a low vaccine uptake. This study aims to describe lactating people’s perceptions toward COVID-19 vaccination uptake and explore facilitators and barriers that inform their COVID-19 vaccination decision-making process. This study adopted an exploratory descriptive qualitative approach, analysing 15 transcripts from interviews with 27 breastfeeding women. The data included eight one-on-one interviews and seven focus group discussions with 19 participants, all recruited online in 2021. The interview guide was developed based on the Health Belief Model, providing a structured framework for exploring participants' perspectives. Four key themes emerged: uncertainty and reservations, information-seeking behaviour, facilitators, and barriers. Uncertainty and reservations were primarily driven by the lack of vaccine safety data specific to breastfeeding, leading some participants to delay or avoid vaccination. While actively seeking credible information, participants encountered several barriers, including conflicting information on social media, limited breastfeeding-specific guidance, and ongoing safety concerns. Despite these challenges, facilitators, such as those with access to trusted information sources, particularly healthcare professionals and public health agencies, helped reassure participants. Those who received clear, evidence-based information felt more confident about the vaccine’s safety during breastfeeding. Concerns about safety, efficacy, limited data, and widespread misinformation continue to hinder vaccine acceptance. However, addressing these barriers through trusted healthcare providers, strengthening public trust in science, and promoting responsible use of social media by government officials and agencies can enhance vaccine confidence and uptake among lactating people.
Galvanic Leaching of Seafloor Massive Sulphides Using MnO₂ in H₂SO₄-NaCl Media
Creators: name: Kowalczuk, Przemyslaw B.
name: Manaig, Dan Oliric
name: Drivenes, Kristian
name: Snook, Ben
name: Aasly, Kurt
name: Kleiv, Rolf Arne
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: This paper reports the leaching of seafloor massive sulphides (SMS) from the Loki’s Castle area at the Arctic Mid-Ocean Ridge in sulphuric acid with manganese dioxide and sodium chloride. The results presented are of various leaching experiments conducted under different conditions in order to optimise the dissolution of copper and silver. It was shown that the main copper bearing minerals in the SMS were chalcopyrite and isocubanite, while silver could occur as an admixture in the crystallographic lattice of sulphides or as disseminated micro inclusions. Based on the results, the leaching mechanism was discussed and elucidated. It was shown that the dissolution of the SMS was mainly due to galvanic interactions between the primary marine minerals of SMS and manganese dioxide. Addition of sodium chloride promoted the extraction mechanism.
Dendrimer-transition metal catalyzed oxidation and reduction reactions
Creators: name: Zweni, Pumza P
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Chemistry, Organic.

description: This project was launched with the aim of developing dendrimer catalysts for oxidation and reduction reactions. Poly(amidoamine) (PAMAM) and poly(propyleneimine) (PPI) dendrimers were of interest because of their well-established synthesis. Chapter 1 describes the fundamentals of dendrimers and provides a brief insight of their application in catalysis. In particular, examples of dendritic catalysts that have been previously employed as oxidation and reduction catalysts are presented. Chapter 2 presents the synthesis and characterization of silica-supported PAMAM dendrimers, their phosphomethylation with Ph2 PCH2OH, and their complexation to palladium complexes. Chapter 3 reports the application of the silica-supported PAMAM-Pd complexes to the oxidation of alkenes to methyl ketones under Wacker-type conditions as well as the use of tBuOOH as the oxidant in these reactions. Chapter 4 discusses the use of the above-mentioned complexes to catalyze the selective hydrogenation of dienes to monoolefins in the presence of H2 under mild reaction conditions. Chapter 5 presents our efforts in modifying PPI dendrimers with the salen moiety to give ligands that are coordinated to the metals Ti and V. Attempts at using the former complexes to promote the epoxidation of alkenes and the latter complexes to catalyze the epoxidation of olefinic alcohols are discussed.
Design and Validity of Randomized Controlled Dental Restorative Trials
Creators: name: Goestemeyer, Gerd
name: Blunck, Uwe
name: Paris, Sebastian
name: Schwendicke, Falk
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: clinical trial
subject: dental restorations
subject: evidence-based dentistry
subject: randomized controlled trial
subject: risk of bias
subject: trial registration
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: The evidence stemming from trials on restorative materials is shaped not only by trial findings, but also trial design and validity. We aimed to evaluate both aspects in randomized controlled dental restorative trials published from 2005–2015. Methods: Using systematic review methodology, we retrieved trials comparing restorative or adhesive dental materials. Two authors independently assessed design, risk of bias, registration status, and findings of trials. Descriptive and regression analyses were performed. Results: 114 studies on 15,321 restorations placed mainly in permanent teeth of 5232 patients were included. Per trial, the median number of patients was 37 (25th/75th percentiles: 30/51). Follow-up was 24 (20/48) months. Seventeen percent of trials reported on sample size calculations, 2% had been registered. Most trials (90%) used US Public Health Service (USPHS) criteria, and had a high risk of bias. More recent trials were more likely to have been registered, to have reported on sample size calculations, to be of low risk of bias, and to use other than USPHS-criteria. Twenty-three percent of trials yielded significant differences between groups. The likelihood of such differences was significantly increased in older studies, studies with potential reporting bias, published in journals with high impact factor (>2), longer follow-up periods, and not using USPHS-criteria. Conclusions: The majority of dental restorative trials published from 2005–2015 had limited validity. Risk of bias decreased in more recent trials. Future trials should aim for high validity, be registered, and use defined and appropriate sample sizes, follow-up periods, and outcome measures.
Transcriptional regulation of 5-HT(1A) receptor gene; Freud-2 a novel repressor of 5-HT(1A) receptor gene
Creators: name: Hadjighassem, Mahmoudreza
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Biology, Neuroscience.

description: The serotonin 1A receptor (5-HT1A) is expressed presynaptically on raphe neurons and works as an inhibitory autoreceptor. It is also expressed postsynaptically in limbic and cortical areas involved in mood and emotional regulation. Alteration in expression and function of 5-HT1A receptors is believed play an important role in etiopathology and treatment of mood disorders such as major depression. 5-HT1A receptor gene regulation was characterized. We have reported a dual repressor element that binds two complexes in non expressing 5-HT1A receptor cells (Freud-1/CC2D1B), but the identity of the second protein was unknown. We identified a mouse Freud-1 homologue (Freud-2/CC2D1B) that binds to the dual repressor element on the 5-HT1A promoter. We show that Freud-2 specifically reduces transcriptional activity of the post synaptic 5-HT1A receptor gene. Knocking down Freud-2 by specific siRNA unregulates expression of 5-HT1A. In addition, we extended our studies to identify and examine the human Freud-2. We show repressor function of Freud-2 in different human cell lines. Further studies on human normal post mortem brains using a specific anti-Freud-2 antibody reveal that Freud-2 is highly expressed in the nucleus of postsynaptic neurons in prefrontal cortex and hippocampus region in human and distributed in grey matter of these regions. We conclude that Freud-2 has a potential role in modulating mood and emotional response by altering the expression of postsynaptic 5-HT1A.
Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P
Creators: name: Hybsier, Sandra
name: Schulz, Torsten
name: Wu, Zida
name: Demuth, Ilja
name: Minich, Waldemar B.;
name: Renko, Kostja
name: Rijntjes, Eddy
name: Köhrle, Josef
name: Strasburger, Christian J.
name: Steinhagen-Thiessen, Elisabeth
name: Schomburg, Lutz
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Selenoprotein P
subject: Selenium
subject: Oxidative stress
subject: Diabetes
subject: Sex
subject: ELISA
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Selenoprotein P (SELENOP) is a liver-derived transporter of selenium (Se) in blood, and a meaningful biomarker of Se status. Se is an essential trace element for the biosynthesis of enzymatically-active selenoproteins, protecting the organism from oxidative damage. The usage of uncalibrated assays hinders the comparability of SELENOP concentrations and their pathophysiological interpretation across different clinical studies. On this account, we established a new sandwich SELENOP-ELISA and calibrated against a standard reference material (SRM1950). The ELISA displays a wide working range (11.6–538.4 µg/L), high accuracy (2.9%) and good precision (9.3%). To verify whether SELENOP correlates to total Se and to SELENOP-bound Se, serum samples from healthy subjects and age-selected participants from the Berlin Aging Study II were analyzed by SELENOP-ELISA and Se quantification. SELENOP was affinity-purified and its Se content was determined from a subset of samples. There was a high correlation of total Se and SELENOP concentrations in young and elderly men, and in elderly women, but not in young women, indicating a specific sexual dimorphism in these biomarkers of Se status in young subjects. The Se content of isolated SELENOP was independent of sex and age (mean±SD: 5.4±0.5). By using this calibrated SELENOP-ELISA, prior reports on pathological SELENOP concentrations in diabetes and obesity are challenged as the reported values are outside reasonable limits. Biomarkers of Se status in clinical research need to be measured by validated assays in order to avoid erroneous data and incorrect interpretations, especially when analyzing young women. The Se content of circulating SELENOP differs between individuals and may provide some important diagnostic information on Se metabolism and status.
Recent development of machine learning-based methods for the prediction of defensin family and subfamily
Creators: name: Charoenkwan, Phasit
name: Schaduangrat, Nalini
name: Mahmud, S. M. Hasan
name: Thinnukool, Orawit
name: Shoombuatong, Watshara
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2022
Subjects: defensins
sequence analysis
bioinformatics
classification
machine learning
feature selection

description: Nearly all living species comprise of host defense peptides called defensins, that are crucial for innate immunity. These peptides work by activating the immune system which kills the microbes directly or indirectly, thus providing protection to the host. Thus far, numerous preclinical and clinical trials for peptide-based drugs are currently being evaluated. Although, experimental methods can help to precisely identify the defensin peptide family and subfamily, these approaches are often time-consuming and cost-ineffective. On the other hand, machine learning (ML) methods are able to effectively employ protein sequence information without the knowledge of a protein’s three-dimensional structure, thus highlighting their predictive ability for the large-scale identification. To date, several ML methods have been developed for the in silico identification of the defensin peptide family and subfamily. Therefore, summarizing the advantages and disadvantages of the existing methods is urgently needed in order to provide useful suggestions for the development and improvement of new computational models for the identification of the defensin peptide family and subfamily. With this goal in mind, we first provide a comprehensive survey on a collection of six state-of-the-art computational approaches for predicting the defensin peptide family and subfamily. Herein, we cover different important aspects, including the dataset quality, feature encoding methods, feature selection schemes, ML algorithms, cross-validation methods and web server availability/usability. Moreover, we provide our thoughts on the limitations of existing methods and future perspectives for improving the prediction performance and model interpretability. The insights and suggestions gained from this review are anticipated to serve as a valuable guidance for researchers for the development of more robust and useful predictors.
description: EXCLI Journal; 21:Doc757; ISSN 1611-2156
Metabolic control and regulation of mitochondrial proton leak: Effects of UCP1 deficiency and aging in mice.
Creators: name: Monemdjou, Shadi.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Biology, Animal Physiology.

description: The overall objective of this thesis was to examine various aspects of the metabolic significance and regulation of the mitochondrial proton leak. The research conducted specifically assesses the influence that leak has on age-associated changes in mitochondria, and the role that the leak plays in facultative energy expenditure of transgenic mice which lack uncoupling protein-1 (UCP1), a well known mediator of the proton leak. Proton leak in mitochondria has been studied for over ten years, but its exact mechanism has not yet been elucidated and only recently has it been realized that it might be mediated by uncoupling proteins (UCPs). UCPs may confer a mechanism for proton leakage and thus affect the efficiency of oxidative phosphorylation. Mice deficient in the gene for mitochondrial UCP1 (Ucp1-deficient mice) are cold-sensitive despite their abundant expression of genes for the isoforms (Ucp2 and Ucp3), and do not become more obese than controls when fed a high fat diet (Enerback et al. 1997) The objective of our work was to analyse the metabolic control and characteristics of proton leak in mitochondria from brown adipose tissue (BAT) of Ucp1-deficient mice and of heterozygote controls in order to establish the role of the UCPs in facultative thermogenesis. (Abstract shortened by UMI.)