cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Glycerol and natural sugar‐derived complex modulate differentially stratum corneum water‐binding properties and structural parameters in an in vitro Raman‐desorption model
Creators: name: Fluhr, Joachim W.
name: Tfayli, Ali
name: Darlenski, Razvigor
name: Darvin, Maxim E.
name: Joly‐Tonetti, Nicolas
name: Lachmann, Nadège
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: dry skin
subject: in vitro model
subject: lipid lateral packing
subject: partially bound water
subject: Raman spectroscopy
subject: beta-sheet signal
subject: stratum corneum hydration
subject: unbound water
subject: water binding capacity
subject: xerosis
classificationCode: 610
subject: Medizin und Gesundheit

description: The epidermal protective functions are closely associated with skin hydration homeostasis. The understanding of different states of water binding is a rising concept in assessing topically applied formulations and their interaction within the stratum corneum (SC). In addition to global water content, primary bound water, partially bound water, and unbound water and barrier-related lipid lateral packing and protein secondary structure can be measured by Raman spectroscopy. This study aimed to establish an in vitro SC model to evaluate differences in the efficacy of a natural sugar-derived complex in combination with glycerol and a botanical extract in modulating SC water binding and structural proteins and barrier lipids. These compounds were selected due to their water-binding and soothing properties. The SC water profiles were assessed at the surface and in 8 mu m SC depth. After a 12-hour hyperhydration and subsequent product incubation the measurements were performed during a 6 hours desiccation phase. The maximal water caption and the time until reaching a steady state are measured as well as water retention and resistance against water loss. Global water content, partially bound, and unbound water, as well as lipid and protein structures were assessed with confocal Raman microspectroscopy. Both the natural sugar-derived mixture and more pronounced, the same mixture with additional glycerol increased all three water-binding parameters at the surface and in 8 mu m SC depth at the beginning and during the desiccation phase. Further addition of botanical extract did not result in an additional increase of the water-binding. All three formulations showed an increase in the lipid lateral packing values prevented the protein alteration as measured by beta-sheets signal compared to blank. The present model is suited for screening studies comparing the specific effects of different compounds on hydration states. The natural sugar-derived mixture Aquaxyl showed evidence for an improvement of all SC hydration states, lipid and protein structure which was further enhanced by the addition of glycerol 5%. This improvement was evidenced at the surface and within the SC for all hydration-related parameters, and the lipid as well the protein structures. The addition of botanical extract phytoessence blue daisy did not show further improvement.
title: The Re-Emergence of the Legitimate Representative of a
 People:
title: Libya, Syria, and Beyond
titleType: Subtitle
Creators: name: Edtmayer, Matthias
Publisher: name: London School of Economics and Political Science (LSE)
Year: 2018
Subjects: subject: K Law (General)

description: In the context of the civil wars in Libya and Syria, a legal term which was well-known during the decolonisation process re-emerged in statements issued by different foreign ministries. Libyan and Syrian opposition groups were recognised by States as ‘the legitimate representative’ of their people. Since, little scholarly attention has been paid to this development. The recognition was perceived as political rhetoric rather than an act of legal significance. Even the re-emergence of the concept of ‘the legitimate representative of a people’ in a United Nations General Assembly (‘UNGA’) resolution passed unnoticed, with its analysis still missing in the existing literature. This article argues that the re-emergence of the concept of ‘the legitimate representative of a people’ in cases outside the decolonisation process might hint at the beginning of a legal development, which allows the assistance and supply of arms to opposition groups recognised as the legitimate representative of a people. It provides an analysis of the statements made by States in regard to UNGA Resolution 67/262 and contends that the legal concept of ‘the legitimate representative of a people’ could evolve in those future cases in which democratically elected groups have been barred from access to power or ousted by coups d’état.
sj-pdf-1-inq-10.1177_00469580211059740 – Supplemental Material for Anesthesia Health System Capacities in Public Hospitals of Punjab, Pakistan
Creators: name: Shahbaz, Sumbal
name: Zakar, Rubeena
name: Fischer, Florian
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material, sj-pdf-1-inq-10.1177_00469580211059740 for Anesthesia Health System Capacities in Public Hospitals of Punjab, Pakistan by Sumbal Shahbaz, Rubeena Zakar and Florian Fischer in INQUIRY: The Journal of Health Care Organization, Provision, and Financing
Additional file 1 of Reconfigurable frequency multipliers based on graphene field-effect transistors
Creators: name: Toral-Lopez, A.
name: Marin, E. G.
name: Pasadas, F.
name: Ganeriwala, M. D.
name: Ruiz, F. G.
name: Jiménez, D.
name: Godoy, A.
Publisher: name: figshare
Year: 2023
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Additional file 1. Supplementary figures.
title: Quantitative determination of concentration profiles of skin components and topically applied oils by tailored multivariate curve resolution‐alternating least squares using in vivo confocal Raman micro‐spectroscopy
Creators: name: Choe, ChunSik
name: Schleusener, Johannes
name: Ri, JinSong
name: Choe, SeHyok
name: Kim, PokSil
name: Lademann, Jürgen
name: Darvin, Maxim E.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: chemometrics
subject: keratin
subject: penetration
subject: skin barrier function
subject: skin hydration
subject: spectra normalization
subject: stratum corneum
subject: tMCR-ALS
classificationCode: 610
subject: Medizin und Gesundheit

description: The main components of the stratum corneum (SC), water, lipids, and proteins, are non-homogeneously distributed throughout the depth. The quantitative determination of their concentration profiles and penetration depth of topically applied substances are urgent topics of dermatological and cosmetic research. Confocal Raman micro-spectroscopy has distinct advantages when determining semi-quantitative concentrations of SC components and topically applied substances non-invasively and in vivo. In this work, we applied a tailored multivariate curve resolution-alternating least squares (tMCR-ALS) method to analyze Raman spectra of the SC in the 2000-4000 cm(-1) region for quantitatively determining the concentrations of water, lipids, proteins, and topically applied oils using substance-related spectral loadings which were allowed to change depth-dependently from the SC's surface toward its bottom. tMCR-ALS makes matching of depth-dependent signal attenuation, that is, the normalization on keratin, unnecessary and requires only a few additional experiments for calibration - Raman spectra of the pure materials and their densities.
Additional file 1 of Long COVID clinical evaluation, research and impact on society: a global expert consensus
Creators: name: Ewing, Andrew G.
name: Joffe, David
name: Blitshteyn, Svetlana
name: Brooks, Anna E. S.
name: Wist, Julien
name: Bar-Yam, Yaneer
name: Bilodeau, Stephane
name: Curtin, Jennifer
name: Duncan, Rae
name: Faghy, Mark
name: Galland, Leo
name: Pretorius, Etheresia
name: Salamon, Spela
name: Buonsenso, Danilo
name: Hastie, Claire
name: Kane, Binita
name: Khan, M. Asad
name: Lal, Amos
name: Lau, Dennis
name: MacIntyre, Raina
name: McFarland, Sammie
name: Munblit, Daniel
name: Nicholson, Jeremy
name: Ollila, Hanna M.
name: Putrino, David
name: Rosario, Alberto
name: Tan, Timothy
Publisher: name: figshare
Year: 2025
Subjects: Medicine
Biotechnology
Cancer
Science Policy

description: Additional file 1.
title: Aneurysmal subarachnoid hemorrhage in Germany between 2005 and 2018: A nationwide observational study
Creators: name: Uhl, Christian
name: Huscher, Doerte
name: Sommerfeld, Jenny
name: Schönberg, Benn
name: Vajkoczy, Peter
name: Dengler, Nora F.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: age
subject: aneurysmal subarachnoid hemorrhage
subject: case fatality
subject: gender-specific differences
subject: incidence
classificationCode: 610
subject: Medizin und Gesundheit

description: Background and purpose In recent decades, the global incidence of aneurysmal subarachnoid hemorrhage (aSAH) has declined. However, significant regional differences exist. We present the first comprehensive analysis of time trends in the incidence of aSAH and case fatality in Germany. Methods All patients hospitalized with aSAH in Germany between 2005 and 2018 were identified using International Classification of Disease, 10th Revision codes I60.0–I60.7. Results A total of 101,105 cases were included. The incidence of aSAH in Germany decreased at a mean annual rate of 0.5% (p = 0.003) from 8.9 per 100,000 population in 2005 to 8.2 in 2018. Over time, incidences of aSAH declined among patients younger than 55 years and patients aged 70–79 years, increased among ages 60–64 years, and remained stable in age groups 65–69 and 85–89 years. This corresponded to an increase in the mean age of aSAH onset from 55.6 (±14.3) to 59.0 (±14.0) years. Throughout the study period, the mean age of aSAH onset was higher in women compared to men (58.3 ± 14.4 years vs. 56.1 ± 14.1 years). There were no changes in in-hospital case fatality (16.2 vs. 16.6%, p = 0.18), but the duration of hospital stay increased significantly from 19.7 to 24.8 days (p < 0.001). The most frequent aSAH-associated aneurysm location was the anterior circulation throughout the entire study period. Conclusions In Germany, the incidence of aSAH decreased between 2005 and 2018, especially in younger parts of the population. This may reflect effects of lifestyle adjustments most pronounced in younger age groups.
sj-pdf-1-mpx-10.1177_17448069211061973 – Supplemental Material for The PKCγ neurons in anterior cingulate cortex contribute to the development of neuropathic allodynia and pain-related emotion
Creators: name: Zhang, Xiao
name: Liu, Peng
name: He, Xiaolan
name: Jiang, Zhenhua
name: Wang, Qun
name: Gu, Nan
name: Lu, Yan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Neuroscience

description: Supplemental Material, sj-pdf-1-mpx-10.1177_17448069211061973 for The PKCγ neurons in anterior cingulate cortex contribute to the development of neuropathic allodynia and pain-related emotion by Xiao Zhang, Peng Liu, Xiaolan He, Zhenhua Jiang, Qun Wang, Nan Gu, and Yan Lu in Molecular Pain
Additional file 1 of Effects of different treatment frequencies of electromagnetic stimulation for urinary incontinence in women: study protocol for a randomized controlled trial
Creators: name: Chen, Chunmei
name: Zhang, Jing
name: Zhang, Hong
name: Li, Haiyan
name: Yu, Jucheng
name: Pei, Yao
name: Fang, Yuan
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Supplementary Material 1.
Supplementary document for Reflection analysis of absorbing film with diffractive structures for incoherent light by rigorous coupled-wave analysis - 5329905.pdf
Creators: name: Hoshino, Tetsuya
name: Banerjee, Saswatee
name: Aoki, Sadao
name: Itoh, Masahide
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: subject: 20501 Classical and Physical Optics
subject: FOS: Physical sciences
subject: 30303 Optical Properties of Materials
subject: FOS: Chemical sciences
subject: 111302 Optical Technology
subject: FOS: Clinical medicine

description: This is Supplement 1.
title: The spectrum of central nervous system involvement in Whipple's disease
Creators: name: Mecklenburg, Jasper
name: Moos, Verena
name: Moter, Annette
name: Siebert, Eberhard
name: Nave, Alexander Heinrich
name: Schneider, Thomas
name: Ruprecht, Klemens
name: Euskirchen, Philipp
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: bacterial infections
subject: cerebrospinal fluid
subject: embolic stroke
subject: hydrocephalus
subject: Whipple's disease
classificationCode: 610
subject: Medizin und Gesundheit

description: Background and purpose To assess the clinical spectrum of central nervous system (CNS) involvement as well as cerebrospinal fluid (CSF) and neuroimaging findings in patients with Whipple's disease (WD) and to analyze the association of neurological symptoms with CSF and imaging findings. Methods Neurological involvement was retrospectively analyzed in a series of 36 patients diagnosed with WD at a single center between 1992 and 2019. Findings of 81 comprehensive CSF examinations from 36 patients, including polymerase chain reaction (PCR) tests for Tropheryma whipplei (TW) in CSF from 35 patients, were systematically evaluated. The prevalence of ischemic stroke in patients with WD was compared to a matched control cohort. Results Neurological symptoms occurred in 23 of 36 (63.9%) patients, with cognitive, motor, and oculomotor dysfunction being most frequent. TW was detected by PCR in CSF of 13 of 22 (59.1%) patients with and four of 13 (30.8%, p = 0.0496) patients without neurological symptoms. Total CSF protein (p = 0.044) and lactate (p = 0.035) were moderately elevated in WD with neurologic symptoms compared with WD without. No intrathecal immunoglobulin synthesis was observed. Three of 36 (8.3%) patients had hydrocephalus due to aqueductal stenosis. Patients with WD had an unexpectedly high prevalence of ischemic stroke (10/36, 27.7%) compared to matched controls (10/360, 3.2%). Conclusions Neurological involvement in patients with WD is common. Detection of TW DNA in CSF is only partly associated with neurological symptoms. Elevated CSF parameters suggest CNS parenchymal infection. Stroke is a hitherto underrecognized manifestation of WD. These findings suggest that mechanisms beyond CNS infection contribute to the spectrum of CNS involvement in WD.
title: Role of autoantibody levels as biomarkers in the management of patients with myasthenia gravis: A systematic review and expert appraisal
Creators: name: Meisel, Andreas
name: Baggi, Fulvio
name: Behin, Anthony
name: Evoli, Amelia
name: Kostera‐Pruszczyk, Anna
name: Mantegazza, Renato
name: Morales, Raul Juntas
name: Punga, Anna Rostedt
name: Sacconi, Sabrina
name: Schroeter, Michael
name: Verschuuren, Jan
name: Crathorne, Louise
name: Holmes, Kris
name: Leite, Maria‐Isabel
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: autoantibodies
subject: biomarkers
subject: myasthenia gravis
classificationCode: 610
subject: Medizin und Gesundheit

description: Background and purpose Although myasthenia gravis (MG) is recognized as an immunoglobulin G autoantibody-mediated disease, the relationship between autoantibody levels and disease activity in MG is unclear. We sought to evaluate this landscape through systematically assessing the evidence, testing the impact of predefined variables on any relationship, and augmenting with expert opinion. Methods In October 2020, a forum of leading clinicians and researchers in neurology from across Europe (Expert Forum for Rare Autoantibodies in Neurology in Myasthenia Gravis) participated in a series of virtual meetings that took place alongside the conduct of a systematic literature review (SLR). Results Forty-two studies were identified meeting inclusion criteria. Of these, 10 reported some correlation between a patient's autoantibody level and disease severity. Generally, decreased autoantibody levels (acetylcholine receptor, muscle-specific kinase, and titin) were positively and significantly correlated with improvements in disease severity (Quantitative Myasthenia Gravis score, Myasthenia Gravis Composite score, Myasthenia Gravis Activities of Daily Living score, Myasthenia Gravis Foundation of America classification). Given the limited evidence, testing the impact of predefined variables was not feasible. Conclusions This first SLR to assess whether a correlation exists between autoantibody levels and disease activity in patients with MG has indicated a potential positive correlation, which could have clinical implications in guiding treatment decisions. However, in light of the limited and variable evidence, we cannot currently recommend routine clinical use of autoantibody level testing in this context. For now, patient's characteristics, clinical disease course, and laboratory data (e.g., autoantibody status, thymus histology) should inform management, alongside patient-reported outcomes. We highlight the need for future studies to reach more definitive conclusions on this relationship.
title: Reduced resilience of brain state transitions in anti‐N‐methyl‐D‐aspartate receptor encephalitis
Creators: name: Von Schwanenflug, Nina
name: Ramirez‐Mahaluf, Juan P.
name: Krohn, Stephan
name: Romanello, Amy
name: Heine, Josephine
name: Prüss, Harald
name: Crossley, Nicolas A.
name: Finke, Carsten
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: autoimmune encephalitis
subject: functional brain states
subject: functional connectivity dynamics
subject: graph analysis
subject: transition trajectories
classificationCode: 610
subject: Medizin und Gesundheit

description: Patients with anti-N-methyl-aspartate receptor (NMDA) receptor encephalitis suffer from a severe neuropsychiatric syndrome, yet most patients show no abnormalities in routine magnetic resonance imaging. In contrast, advanced neuroimaging studies have consistently identified disrupted functional connectivity in these patients, with recent work suggesting increased volatility of functional state dynamics. Here, we investigate these network dynamics through the spatiotemporal trajectory of meta-state transitions, yielding a time-resolved account of brain state exploration in anti-NMDA receptor encephalitis. To this end, resting-state functional magnetic resonance imaging data were acquired in 73 patients with anti-NMDA receptor encephalitis and 73 age- and sex-matched healthy controls. Time-resolved functional connectivity was clustered into brain meta-states, giving rise to a time-resolved transition network graph with states as nodes and transitions between brain meta-states as weighted, directed edges. Network topology, robustness and transition cost of these transition networks were compared between groups. Transition networks of patients showed significantly lower local efficiency (t = -2.41, p(FDR) = .029), lower robustness (t = -2.01, p(FDR) = .048) and higher leap size (t = 2.18, p(FDR) = .037) compared with controls. Furthermore, the ratio of within-to-between module transitions and state similarity was significantly lower in patients. Importantly, alterations of brain state transitions correlated with disease severity. Together, these findings reveal systematic alterations of transition networks in patients, suggesting that anti-NMDA receptor encephalitis is characterized by reduced stability of brain state transitions and that this reduced resilience of transition networks plays a clinically relevant role in the manifestation of the disease.
The Success of Projecting and Implementing Quality System in the Macedonian Companies
Creators: name: Mitreva, Elizabeta
name: Taskov, Nako
name: Filiposki, Oliver
name: Lazarevski, Ilija
name: Gjorshevski, Hristijan
Publisher: name: UIKTEN
Year: 2017
Subjects: quality system
internal standardization
certification
model and innovation

description: TEM Journal; Vol 6, No 2, 2017. ISSN 2217-8309
description: The research in this paper has been done with the aim to analyse the current condition of the Macedonian companies, in the domains of projecting, implementing and certifying the quality system. The received data from the research has united the experiences and the realities of a number of certified organizational systems in Macedonia. The data analysis, as well as the principles and the strategies derived from the research, have helped in the process of creating a model for improvement of the organizational performances. They also gave useful directions for the process of defining the measures for creating sustainable business systems, and in many other areas such as: encouraging innovations, strengthening the relations among the companies and the scientific research work.
sj-docx-2-jicm-10.1177_08850666211066799 - Supplemental material for High- Versus Low-Dose Dexamethasone for the Treatment of COVID-19-Related Acute Respiratory Distress Syndrome: A Multicenter, Randomized Open-Label Clinical Trial
Creators: name: Maskin, Luis Patricio
name: Bonelli, Ignacio
name: Olarte, Gabriel Leonardo
name: Palizas, Fernando
name: Velo, Agostina E
name: Lurbet, María Fernanda
name: Lovazzano, Pablo
name: Kotsias, Sophia
name: Attie, Shiry
name: Lopez Saubidet, Ignacio
name: Baredes, Natalio D
name: Setten, Mariano
name: Rodriguez, Pablo Oscar
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 110203 Respiratory Diseases

description: Supplemental material, sj-docx-2-jicm-10.1177_08850666211066799 for High- Versus Low-Dose Dexamethasone for the Treatment of COVID-19-Related Acute Respiratory Distress Syndrome: A Multicenter, Randomized Open-Label Clinical Trial by Luis Patricio Maskin, Ignacio Bonelli, Gabriel Leonardo Olarte, Fernando Palizas, Agostina E Velo, María Fernanda Lurbet, Pablo Lovazzano, Sophia Kotsias, Shiry Attie, Ignacio Lopez Saubidet, Natalio D Baredes, Mariano Setten and Pablo Oscar Rodriguez in Journal of Intensive Care Medicine
Automated PCB Inspection System
Creators: name: BUKHARI, Syed Usama
name: BONDREA, Ioan
name: BRAD, Remus
Publisher: name: UIKTEN
Year: 2017
Subjects: Printed Circuit Board
Automated Visual Inspection
Computer Vision
Quality Assurance

description: TEM Journal; Vol 6, No 2, 2017. ISSN 2217-8309
description: Development of an automated PCB inspection system as per the need of industry is a challenging task. In this paper a case study is presented, to exhibit, a proposed system for an immigration process of a manual PCB inspection system to an automated PCB inspection system, with a minimal intervention on the existing production flow, for a leading automotive manufacturing company. A detailed design of the system, based on computer vision followed by testing and analysis was proposed, in order to aid the manufacturer in the process of automation.
title: Non-abelian holonomy of majorana zero modes coupled to a chaotic quantum dot
Creators: name: Geier, Max
name: Krøjer, Svend
name: Von Oppen, Felix
name: Marcus, Charles M.
name: Flensberg, Karsten
name: Brouwer, Piet W.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Majorana bound states
subject: Quantum chaos
subject: Quantum billiards
subject: Quantum dots
subject: Topological superconductors
subject: Geometry
subject: Random matrix theory
classificationCode: 539
subject: Moderne Physik

description: If a quantum dot is coupled to a topological superconductor via tunneling contacts, each contact hosts a Majorana zero mode in the limit of zero transmission. Close to a resonance and at a finite contact transparency, the resonant level in the quantum dot couples the Majorana modes, but a ground-state degeneracy per fermion parity subspace remains if the number of Majorana modes coupled to the dot is five or larger. Upon varying shape-defining gate voltages while remaining close to resonance, a nontrivial evolution within the degenerate ground-state manifold is achieved. We characterize the corresponding non-Abelian holonomy for a quantum dot with chaotic classical dynamics using random matrix theory and discuss measurable signatures of the non-Abelian time evolution.
(Outer) Rings And Breaks In Disk Galaxy Profiles
Creators: name: Erwin, Peter
Publisher: name: Zenodo
Year: 2018

description: I discuss what is currently known about connections between outer rings and the underlying radial profiles of galactic disks. Correlations between rings and truncations (Type II profiles, with downbending breaks in the surface-brightness profile) allow us to distinguish between two general models of profile formation. In many early-type disk galaxies, outer rings coincide with downbending breaks, suggesting that ring formation is directly linked to break formation, most likely due to an outer Lindblad resonance. But outer rings also coexist with Type I profiles (where no break is present), and in some cases with Type II profiles where the break is well outside the ring; the latter are indications that many truncations, especially in late-type spirals, are due to a different mechanism, such as a star-formation threshold. I will also discuss how rings can potentially produce false breaks in Type I profiles, especially in edge-on galaxies, as well as potential connections between outer rings and anti-truncated (Type III) profiles.
sj-pdf-1-aei-10.1177_15345084211063533 – Supplemental material for The Dyslexia Marker Test for Children: Development and Validation of a New Test
Creators: name: Nergård-Nilssen, Trude
name: Friborg, Oddgeir
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: Education
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental material, sj-pdf-1-aei-10.1177_15345084211063533 for The Dyslexia Marker Test for Children: Development and Validation of a New Test by Trude Nergård-Nilssen and Oddgeir Friborg in Assessment for Effective Intervention
Additional file 1 of Neutrophil infiltration and microglial shifts in sepsis induced preterm brain injury: pathological insights
Creators: name: Zhu, Jinjin
name: He, Tiantian
name: Huang, Ziwei
name: Yu, Wenkai
name: Lu, Jinnan
name: Zhang, Shan
name: Zhang, Xiaoli
name: Dong, Huifang
name: Xu, Yiran
name: Wang, Xiaoyang
name: Zhu, Changlian
Publisher: name: figshare
Year: 2025
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Hematology

description: Supplementary Material 1
title: Anti-CD20 therapy for multiple sclerosis-associated uveitis: A case series
Creators: name: Stascheit, Frauke
name: Rübsam, Anne
name: Otto, Carolin
name: Meisel, Andreas
name: Ruprecht, Klemens
name: Pleyer, Uwe
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: anti-CD20 therapy
subject: multiple sclerosis
subject: ocrelizumab
subject: retinal fluorescein angiography
subject: rituximab
subject: uveitis
classificationCode: 610
subject: Medizin und Gesundheit

description: Background and purpose: Approximately 1% of patients with multiple sclerosis (MS) have uveitis, but data on the effects of immunotherapies for MS on MS-associated uveitis are scarce. The aim of this study was to investigate the ophthalmological outcomes in patients with MS-associated uveitis treated with anti-CD20 therapy. Methods: A retrospective study of 12 eyes of six patients with MS-associated uveitis, refractory to previous immunotherapies, was conducted. Uveitis activity was assessed before initiation of anti-CD20 therapy and at regular follow-up visits. Primary outcome measures were: vitreous haze score; retinal vasculitis score, determined on fluorescein angiography images; macular edema, as quantified by central retinal thickness (CRT) on optical coherence tomography; and visual acuity (VA). Secondary outcomes included number of annualized uveitis or MS relapses, disease activity on cerebral magnetic resonance imaging (cMRI) and Expanded Disability Status Scale (EDSS) score. Results: After a median (interquartile range [IQR]) treatment time of 28.5 (8–43) months, anti-CD20 therapy was associated with an improvement of vitreous haze score (p = 0.002), retinal vasculitis score (p = 0.001), CRT (p = 0.002), and VA (p = 0.007). The median (IQR) annualized uveitis relapse rate declined from 0.59 (0.56–0.94) before to 0 (0–0.49) after the start of anti-CD20 therapy. The median (IQR) annualized MS relapse rate declined from 0.62 (0.26–2.84) before to 0 (0–0) after the start of anti-CD20 therapy. After initiation of anti-CD20 therapy, there was no disease activity on cMRI, and EDSS score improved (n = 2) or remained stable (n = 4). No severe adverse events were observed. Conclusion: These findings suggest that anti-CD20 therapy may be a valuable treatment option for MS-associated uveitis.
Additional file 1 of Association of DOK3 and infiltrated tumor-associated macrophages with risk for the prognosis of Porphyromonas gingivalis-infected oral cancer: a 12-year data analysis of 200 patients from a tertiary teaching hospital, Urumqi, China
Creators: name: Li, Chenxi
name: Li, Muqiu
name: Wei, Wei
name: Wang, Zhengye
name: Yu, Jingwen
name: Gong, Zhongcheng
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1.
sj-docx-6-rse-10.1177_07419325211063491 – Supplemental material for A Systematic Review of Meta-Analyses in Special Education: Exploring the Evidence Base for High-Leverage Practices
Creators: name: Nelson, Gena
name: Cook, Sara Cothren
name: Zarate, Kary
name: Powell, Sarah R.
name: Maggin, Daniel M.
name: Drake, Kevallyn R.
name: Kiss, Allyson J.
name: Ford, Jeremy W.
name: Sun, Lin
name: Espinas, Daniel R.
Publisher: name: SAGE Journals
Year: 2021
Subjects: Education
Psychology not elsewhere classified
Special Education and Disability

description: Supplemental material, sj-docx-6-rse-10.1177_07419325211063491 for A Systematic Review of Meta-Analyses in Special Education: Exploring the Evidence Base for High-Leverage Practices by Gena Nelson, Sara Cothren Cook, Kary Zarate, Sarah R. Powell, Daniel M. Maggin, Kevallyn R. Drake, Allyson J. Kiss, Jeremy W. Ford, Lin Sun and Daniel R. Espinas in Remedial and Special Education
title: Clinical characteristics, treatments, outcome, and prognostic factors of severe autoimmune encephalitis in the intensive care unit: Standard treatment and the value of additional plasma cell–depleting escalation therapies for treatment‐refractory patients
Creators: name: Schwarz, Lisa
name: Akbari, Nilufar
name: Prüss, Harald
name: Meisel, Andreas
name: Scheibe, Franziska
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: autoimmune encephalitis
subject: bortezomib
subject: daratumumab
subject: intensive care unit
subject: plasma cell depletion
classificationCode: 610
subject: Medizin und Gesundheit

description: Background and purpose To investigate severe autoimmune encephalitis (AE) in the intensive care unit (ICU) with regard to standard treatment in responsive patients and additional escalation therapies for treatment-refractory cases. Methods This retrospective, single-center study analyzed medical records of ICU-dependent AE patients for clinical characteristics, treatments, prognostic factors, and neurological outcome as quantified by modified Rankin Scale (mRS) and Clinical Assessment Scale for Autoimmune Encephalitis (CASE). Results From 40 enrolled patients (median age = 52 years; range = 16–89 years) with AE mediated by neuronal surface antibodies (nsAb; 90%) and AE with onconeuronal antibodies (10%), 98% received first-line therapy. Of those, 62% obtained additional second-line therapy, and 33% received escalation therapy with bortezomib and/or daratumumab. Good neurological outcome, defined as mRS = 0–2, was observed in 47% of AE with nsAb (CASE = 5), 77% of anti-N-methyl D-aspartate receptor encephalitis patients (CASE = 1), whereas AE patients with onconeuronal antibodies had the poorest outcome (mRS = 6, 100%). Treatment-refractory AE patients with nsAb requiring escalation therapy achieved similarly good recovery (mRS = 0–2, 39%, CASE = 3) as patients improving without (mRS = 0–2, 54%, CASE = 4), although they presented a higher disease severity at disease maximum (mRS = 5 100% versus 68%, CASE = 24 versus 17; p = 0.0036), had longer ICU stays (97 versus 23 days; p = 0.0002), and a higher survival propability during follow-up (p = 0.0203). Prognostic factors for good recovery were younger age (p = 0.025) and lack of preexisting comorbidities (p = 0.011). Conclusions Our findings suggest that treatment-refractory AE patients with nsAb in the ICU can reach similarly good outcomes after plasma cell–depleting escalation therapy as patients already responding to standard first- and/or second-line therapies.
The Dust Forecast, Predicting The Dust Attenuation In Spiral Disk Galaxies
Creators: name: Holwerda, B.W.
name: W.C. Keel
Publisher: name: Zenodo
Year: 2018

description: Interstellar dust is still a dominant uncertainty in Astronomy, limiting precision in e.g.,

cosmological distance estimates and models of how light is re-processed within a galaxy.

When a foreground galaxy serendipitously overlaps a more distant one, the latter back-

lights the dusty structures in the nearer foreground galaxy. Such an overlapping or

occulting galaxy pair can be used to measure the distribution of dust in the closest

galaxy with great accuracy. The STARSMOG program uses Hubble to map the dis-

tribution of dust in foreground galaxies in fine (<100 pc) detail. Integral Field Unit

(IFU) observations will map the effective extinction curve, disentangling the role of

fine-scale geometry and grain composition on the path of light through a galaxy. The

overlapping galaxy technique promises to deliver a clear understanding of the dust in

galaxies: geometry, a probability function of dimming as a function of galaxy mass and

radius, and its dependence on wavelength.
title: The single-cell transcriptional landscape of lung carcinoid tumors
Creators: name: Bischoff, Philip
name: Trinks, Alexandra
name: Wiederspahn, Jennifer
name: Obermayer, Benedikt
name: Pett, Jan Patrick
name: Jurmeister, Philipp
name: Elsner, Aron
name: Dziodzio, Tomasz
name: Rückert, Jens‐Carsten
name: Neudecker, Jens
name: Falk, Christine
name: Beule, Dieter
name: Sers, Christine
name: Morkel, Markus
name: Horst, David
name: Klauschen, Frederick
name: Blüthgen, Nils
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: carcinoid tumors
subject: lung cancer
subject: neuroendocrine tumors
subject: single-cell transcriptomics
subject: tumor microenvironment
classificationCode: 610
subject: Medizin und Gesundheit

description: Lung carcinoid tumors, also referred to as pulmonary neuroendocrine tumors or lung carcinoids, are rare neoplasms of the lung with a more favorable prognosis than other subtypes of lung cancer. Still, some patients suffer from relapsed disease and metastatic spread. Several recent single-cell studies have provided detailed insights into the cellular heterogeneity of more common lung cancers, such as adeno- and squamous cell carcinoma. However, the characteristics of lung carcinoids on the single-cell level are yet completely unknown. To study the cellular composition and single-cell gene expression profiles in lung carcinoids, we applied single-cell RNA sequencing to three lung carcinoid tumor samples and normal lung tissue. The single-cell transcriptomes of carcinoid tumor cells reflected intertumoral heterogeneity associated with clinicopathological features, such as tumor necrosis and proliferation index. The immune microenvironment was specifically enriched in noninflammatory monocyte-derived myeloid cells. Tumor-associated endothelial cells were characterized by distinct gene expression profiles. A spectrum of vascular smooth muscle cells and pericytes predominated the stromal microenvironment. We found a small proportion of myofibroblasts exhibiting features reminiscent of cancer-associated fibroblasts. Stromal and immune cells exhibited potential paracrine interactions which may shape the microenvironment via NOTCH, VEGF, TGF beta and JAK/STAT signaling. Moreover, single-cell gene signatures of pericytes and myofibroblasts demonstrated prognostic value in bulk gene expression data. Here, we provide first comprehensive insights into the cellular composition and single-cell gene expression profiles in lung carcinoids, demonstrating the noninflammatory and vessel-rich nature of their tumor microenvironment, and outlining relevant intercellular interactions which could serve as future therapeutic targets.
Zerschnittene Bilder. Die drei Fassungen von Dziga Vertovs Tri pesni o Lenine (1934/35, 1938 und 1970)
Creators: name: Heftberger, Adelheid
Publisher: name: unknown
Year: 2011
Subjects: subject: Russia
subject: Area studies

description: On the versions of Dziga Vertovs film "Three Songs on Lenin".
sj-docx-3-eae-10.1177_0958305X211069654 - Supplemental material for Investigating environmental regulation effects on technological innovation: A meta-regression analysis
Creators: name: Sun, Zhuanlan
name: Zhu, Demi
Publisher: name: SAGE Journals
Year: 2021
Subjects: Geography

description: Supplemental material, sj-docx-3-eae-10.1177_0958305X211069654 for Investigating environmental regulation effects on technological innovation: A meta-regression analysis by Zhuanlan Sun and Demi Zhu in Energy & Environment
Additional file 1 of Spatiotemporal variations and determinants of overweight/obesity among women of reproductive age in urban India during 2005-2021
Creators: name: Singh, Aditya
name: Let, Subhojit
name: Tiwari, Seema
name: Chakrabarty, Mahashweta
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Supplementary Material 1
sj-docx-1-jop-10.1177_02698811211064720 – Supplemental material for The effects of psilocybin on cognitive and emotional functions in healthy participants: Results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation
Creators: name: Rucker, James J
name: Marwood, Lindsey
name: Ajantaival, Riikka-Liisa J
name: Bird, Catherine
name: Eriksson, Hans
name: Harrison, John
name: Lennard-Jones, Molly
name: Mistry, Sunil
name: Saldarini, Francesco
name: Stansfield, Susan
name: Tai, Sara J
name: Williams, Sam
name: Weston, Neil
name: Malievskaia, Ekaterina
name: Young, Allan H
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)

description: Supplemental material, sj-docx-1-jop-10.1177_02698811211064720 for The effects of psilocybin on cognitive and emotional functions in healthy participants: Results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation by James J Rucker, Lindsey Marwood, Riikka-Liisa J Ajantaival, Catherine Bird, Hans Eriksson, John Harrison, Molly Lennard-Jones, Sunil Mistry, Francesco Saldarini, Susan Stansfield, Sara J Tai, Sam Williams, Neil Weston, Ekaterina Malievskaia and Allan H Young in Journal of Psychopharmacology
Additional file 1 of Factors influencing the development of nursing professionalism: a descriptive qualitative study
Creators: name: He, Xingyue
name: Mao, Ya
name: Cao, Huili
name: Li, Linbo
name: Wu, Yanming
name: Yang, Hui
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Supplementary Material 1
Additional file 2 of Neutrophil infiltration and microglial shifts in sepsis induced preterm brain injury: pathological insights
Creators: name: Zhu, Jinjin
name: He, Tiantian
name: Huang, Ziwei
name: Yu, Wenkai
name: Lu, Jinnan
name: Zhang, Shan
name: Zhang, Xiaoli
name: Dong, Huifang
name: Xu, Yiran
name: Wang, Xiaoyang
name: Zhu, Changlian
Publisher: name: figshare
Year: 2025
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Hematology

description: Supplementary Material 2
Supplementary document for Closed aperture CW Z-scan of L-tryptophan for determination of optical nonlinearity in the thermal regime - 5350082.pdf
Creators: name: Tarek, Sarfuddin
name: Faruque, Syed
name: Sharafuddin, Sharif
name: Hasan, Khan
name: Hossain, A K M
name: Ara, Hosne
name: Biswas, Manash
name: Haque, Yasmeen
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: subject: 20503 Nonlinear Optics and Spectroscopy
subject: FOS: Physical sciences

description: Percentage of fitting of tryptophan and water Z-scan data
Love at Loss: Jean-Luc Marion's Concept of Erotic Reduction and Paul Thomas Anderson's "Magnolia"
Creators: name: Schulzki, Irina
Publisher: name: Verlag Traugott Bautz
Year: 2015
Subjects: subject: Cinematography
subject: Motion pictures--Philosophy

description: In the following remarks, I introduce Jean-Luc Marion's categories of his phenomenology of the given and of the erotic in the narrow context of one film, Paul Thomas Anderson's "Magnolia" (1999). Apart from using Marion's terminology as a set of analytical categories, I also apply his method of the socalled 'third' phenomenological reduction, the reduction to givenness, to inquire into the central topic of this article – love at loss.
Additional file 1 of The urgent need for patients’ diagnoses and outcome feedback in Germany’s emergency medical services — insights from a web-based survey
Creators: name: Kästner, Anika
name: Lücker, Petra
name: Fischer, Lutz
name: Laslo, Timm
name: Henkel, Berthold
name: Ehleben, Jennifer
name: Hoffmann, Wolfgang
name: van den Berg, Neeltje
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Neuroscience
subject: Biotechnology
subject: Science Policy
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Additional file 2 of Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer
Creators: name: Li, Yanni
name: Sundquist, Kristina
name: Vats, Sakshi
name: Hong, Mun-Gwan
name: Wang, Xiao
name: Chen, Yilun
name: Hedelius, Anna
name: Saal, Lao H.
name: Sundquist, Jan
name: Memon, Ashfaque A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Table S1. MtDNA mutational characteristics of 86 breast biopsies. Table S2. Haplogroup associated disease-causing mutations identified in our study population. Table S3. MtDNA mutational characteristics of unmatched 36 breast biopsies. Table S4. The dN/dS of de novo heteroplasmic mutations. Table S5. Baseline characteristics stratified by incident and no cancers. Table S6. Baseline characteristics stratified by shortlisted mtDNA mutations. Table S7. Hazard ratios and 95% confidence intervals of mortality associated with mutations among breast cancer patient. Figure S1. The mtDNA mutation profiles of 50 matched biopsy-whole blood pairs. Figure S2. The alteration probability of mtDNA mutational signature with respect to 96 trinucleotides. Figure S3. The HL distribution of mt.1888G > A and mt.16093T > C mutation. Figure S4. Kaplan-Meier plot of breast cancer mortality stratified by A. mt.16093T > C and B. mt.1888G > A mutation.
Additional file 1 of Missing nurses cause missed care: is that it? Non-trivial configurations of reasons associated with missed care in Austrian hospitals – a qualitative comparative analysis
Creators: name: Cartaxo, Ana
name: Mayer, Hanna
name: Eberl, Inge
name: Bergmann, Johannes M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1.
Recordare, Virgo Mater: devoção musical mariana na Sé de Évora no século XVIII
Creators: name: Henriques, Luís
Publisher: name: unknown
Year: 2017
Subjects: subject: Musicology

description: Desde a sua origem, a Sé de Évora constitui um importante centro de devoção mariana não só no perímetro urbano, como também nas freguesias do termo, e cuja dedicação do altar-mor da catedral a Nossa Senhora da Assunção conferiu-lhe lugar central nesse culto. É precisamente a partir do ofertório mariano Recordare, Virgo Mater que se encontra uma importante relação musical deste culto na catedral de Évora. Esta rubrica foi posta em música por vários compositores ao longo do século XVIII, cuja versão mais antiga conhecida actualmente pertence ao compositor e mestre de capela da catedral Diogo Dias Melgaz. Outras versões (várias de autor desconhecido) apontam para uma continuidade na escrita desta rubrica ao longo do século XVIII, sendo o estilo de escrita musical actualizado ao gosto da época. Desta forma, tomando como elemento condutor o ofertório Recordare, Virgo Mater, este estudo pretende enquadrar a composição destas obras, integrando-as no culto mariano na Sé de Évora durante o século XVIII, traçando simultaneamente o seu espaço contextual dentro da liturgia musical da catedral.
sj-pdf-1-vmj-10.1177_1358863X211047270 – Supplemental material for Apixaban Discontinuation for Invasive Or major Surgical procedures (ADIOS): A prospective cohort study
Creators: name: Merli, Geno J
name: Kraft, Walter K
name: Eraso, Luis H
name: Galanis, Taki
name: Thomson, Lynda J
name: Ouma, Geoffrey O
name: Viscusi, Eugene
name: Gong, Jerald Z
name: Lam, Edwin
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-vmj-10.1177_1358863X211047270 for Apixaban Discontinuation for Invasive Or major Surgical procedures (ADIOS): A prospective cohort study by Geno J Merli, Walter K Kraft, Luis H Eraso, Taki Galanis, Lynda J Thomson, Geoffrey O Ouma, Eugene Viscusi, Jerald Z Gong and Edwin Lam in Vascular Medicine