title: ÐÐ·ÑÑÐµÐ½Ð¸Ðµ Ð°Ð½ÑÐ¸Ð¼Ð¸ÐºÑÐ¾Ð±Ð½ÑÑ ÑÐ²Ð¾Ð¹ÑÑÐ² Ð¿Ð¾Ð»Ð¸ÑÑÐ¾ÑÐ°Ð»ÐºÐ¸Ð»Ð¾Ð²ÑÑ ÑÑÐ¸ÑÐ¾Ð² N-Ð·Ð°Ð¼ÐµÑÑÐ½Ð½ÑÑ Ð¸Ð¼Ð¸Ð´Ð¾Ð² Ð¼Ð°Ð»ÐµÐ¾Ð¿Ð¸Ð¼Ð°ÑÐ¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ Ð½Ð° ÑÐµÑÑ-ÐºÑÐ»ÑÑÑÑÐ°Ñ Ð¼Ð¸ÐºÑÐ¾Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð¼Ð¾Ð²
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Investigation of the antimicrobial properties of polyfluoroalkyl ethers of N-substituted maleopymaric acid imides on test cultures of microorganisms
Creators: name: Ð¡ÑÐ¹ Ð¥ÑÐ°Ð²ÑÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2023
Subjects: Ð°Ð½ÑÐ¸Ð¼Ð¸ÐºÑÐ¾Ð±Ð½Ð°Ñ ÑÐ²Ð¾Ð¹ÑÑÐ²Ð°
ÐºÐ°Ð½Ð¸ÑÐ¾Ð»Ñ
ÑÐ¼Ð¾Ð»ÑÐ½ÑÐµ ÐºÐ¸ÑÐ»Ð¾ÑÑ
N-ÑÐµÐ½Ð¸Ð»Ð¸Ð¼Ð¸Ð´ Ð¼Ð°Ð»ÐµÐ¾Ð¿Ð¸Ð¼Ð°ÑÐ¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ
N-ÑÐµÐ½Ð¸Ð»Ð¸Ð¼Ð¸Ð´
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Ð´Ð¾Ð´ÐµÐºÐ°ÑÑÐ¾ÑÐ³ÐµÐ¿ÑÐ¸Ð»Ð¼Ð°Ð»ÐµÐ¾Ð¿Ð¸Ð¼Ð°ÑÐ°ÑÐ°
swiss Adme
pass Online
antimicrobial properties
rosin
resin acids
N-phenylimide maleopimaric acid
N-phenylimide
octafluoropentylmaleopimarate
dodecafluoropeptylmaleopimarate
Swiss Adme
Pass Online

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description: This work is devoted to the study of chemical synthesis of polyfluoroalkyl ethers of N-substituted maleopymaric acid imides and investigation of their antimicrobial properties. Research objectives: 1)To synthesize polyfluoroalkyl esters of N-substituted maleopymaric acid imides. 2) Determine the antimicrobial activity of N-substituted imide esters of maleopimaric acid. 3) Analyze biological activity of polyfluoroalkyl ethers of N-substituted maleopymaric acid imides by means of PASS Online software and determine their physico-chemical properties by means of SwissADME software. Researches have been carried out on the base of WSBiPP. New chemical compounds polyfluoroalkyl esters of maleopymaric acid, N-phenylimides of polyfluoroalkyl esters of maleopymaric acid (IIa and IIb) and N-phenylimide of maleopymaric acid(III) were synthesized. Lipophilicity and hydrophobicity of the compounds studied were evaluated using SwissADME software and predicted biological activity using PASS online software. Bactericidal properties of newly synthesized compounds against bacteria, yeasts and molds were studied. The following databases were used for literature review: eLIBRARY.RU, CNKI, Scopus, ConsultantPlus, patents.google.com. Statistical processing of experimental data was carried out using WPS Office software package.