cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Characterization of proton irradiated 3D-DDTC pixel sensor prototypes fabricated at FBK
Creators: name: La Rosa, A.
name: Boscardin, M.
name: Cobal, M.
name: Betta, G. -F. Dalla
name: Da Via, C.
name: Darbo, G.
name: Gallrapp, C.
name: Gemme, C.
name: Huegging, F.
name: Janssen, J.
name: Micelli, A.
name: Pernegger, H.
name: Povoli, M.
name: Wermes, N.
name: Zorzi, N.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: In this paper we discuss results relevant to 3D Double-Side Double Type Column (3D-DDTC) pixel sensors fabricated at FBK (Trento, Italy) and oriented to the ATLAS upgrade. Some assemblies of these sensors featuring different columnar electrode configurations (2, 3, or 4 columns per pixel) and coupled to the ATLAS FEI3 read-out chip were irradiated up to large proton fluences and tested in laboratory with radioactive sources. In spite of the non optimized columnar electrode overlap, sensors exhibit reasonably good charge collection properties up to an irradiation fluence of 2 x 10**15 neq/cm2, while requiring bias voltages in the order of 100 V. Sensor operation is further investigated by means of TCAD simulations which can effectively explain the basic mechanisms responsible for charge loss after irradiation.
description: Preprint submitted to Nuclear Instruments and Methods A, 11 pages, 13 figs
Identifying outlying groups through residual analysis and its application to healthcare expenditure
Creators: name: Kwon, Hyukdong
name: Yu, Jihnhee
name: Li, Mingliang
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Neuroscience
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Traditional regression analysis primarily aims to describe the overall relationship between variables, often overlooking unexplainable aspects by design. Our focus is on these unexplained aspects, leveraging them to identify disparity groups with outlying behavior that deviate from the established model. We introduce a data-driven method for identifying such groups using group studentized residuals, which we term the mean squared of external studentized residuals. We apply this method to investigate disparities within healthcare markets, examining healthcare purchasing behavior and identifying the characteristics of disparity groups.
Nonscattering solutions and blowup at infinity for the critical wave equation
Creators: name: Donninger, Roland
name: Krieger, Joachim
Publisher: name: arXiv
Year: 2012
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 35L05, 35L71

description: We consider the critical focusing wave equation $(-\partial_t^2+Δ)u+u^5=0$ in $\R^{1+3}$ and prove the existence of energy class solutions which are of the form [u(t,x)=t^\fracμ{2}W(t^μx)+η(t,x)] in the forward lightcone ${(t,x)\in\R\times \R^3: |x|\leq t, t\gg 1}$ where $W(x)=(1+(1/3)|x|^2)^{-(1/2)}$ is the ground state soliton, $μ$ is an arbitrary prescribed real number (positive or negative) with $|μ|\ll 1$, and the error $η$ satisfies [|\partial_t η(t,\cdot)|_{L^2(B_t)} +|\nabla η(t,\cdot)|_{L^2(B_t)}\ll 1,\quad B_t:={x\in\R^3: |x|
description: 53 pages, final version, some additional typos have been fixed
Translation and validation of the Hearing Environments and Reflection on Quality of Life (HEAR-QL) questionnaire for preschool children in Dutch
Creators: name: Batthyany, Christina
name: van der Schroeff, Marc
name: Vroegop, Jantien
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Mental Health

description: Early diagnosis, intervention and consistent follow-up of hearing loss is of great importance in children, given the broad impact of untreated childhood hearing loss. Currently, no hearing-specific QOL proxy questionnaire exists for preschool children with hearing loss in the Dutch language. Therefore, the aim of this study was to translate and validate the Preschool HEAR-QL questionnaire into Dutch. Translation was conducted according the forward–backward procedure. Parents or caregivers of 60 normal-hearing children and 50 children with bilateral hearing loss aged 2–6 years old were invited to digitally complete the questionnaire. The Preschool HEAR-QL questionnaire showed good discriminant validity between the normal-hearing and the hearing loss group, for its total score and some subscales. We concluded satisfying internal consistency given Cronbach’s alpha values being above 0.70, nearly all alpha if item deleted values approaching the overall values, and item-subscale correlations above 0.30. Test-retest reliability was satisfying with all intraclass correlation coefficients being greater than 0.70. This Dutch hearing-specific QOL proxy questionnaire can play an important role in the management and follow-up of early childhood hearing loss in Dutch health care and hearing centers. Future research on clinical data will further verify its utility in clinical practice.
Idempotent functors that preserve cofiber sequences and split suspensions
Creators: name: Strom, Jeffrey
Publisher: name: arXiv
Year: 2012
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 55P60, 55P62

description: We show that an $f$-localization functor $L_f$ commutes with cofiber sequences of $(N-1)$-connected finite complexes if and only if its restriction to the collection of $(N-1)$-connected finite complexes is $R$-localization for some unital subring $R\sseq\mathbb{Q}$. This leads to a homotopy-theoretical characterization of the rationalization functor: the restriction of $L_f$ to simply-connected spaces (not just the finite complexes) is rationalization if and only if $L_f(S^2)$ is nontrivial and simply-connected, $L_f$ preserves cofiber sequences of simply-connected finite complexes, and for each simply-connected finite complex $K$, $\s^k L_f(K)$ splits as a wedge of copies of $L_f(S^n)$ for large enough $k$ and various values of $n$.
description: 10 pages
MPEC 2023-H177 : 2013 HL = 2020 SH1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Equidistribution towards the Green current in big cohomology classes
Creators: name: Bayraktar, Turgay
Publisher: name: arXiv
Year: 2012
Subjects: subject: Complex Variables (math.CV)
subject: Algebraic Geometry (math.AG)
subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37F10, 32H50, 32H04

description: We study limiting distribution of the sequence of pull-backs of smooth $(1,1)$ forms and positive closed currents by meromorphic self-maps of compact Kähler manifolds.
description: Introduction is revised, some typos are corrected
Identifying the natural compound Catechin from tropical mangrove plants as a potential lead candidate against 3CLpro from SARS-CoV-2: An integrated in silico approach
Creators: name: Jha, Rajat Kumar
name: Khan, Rameez Jabeer
name: Parthiban, A.
name: Singh, Ekampreet
name: Jain, Monika
name: Amera, Gizachew Muluneh
name: Singh, Rashmi Prabha
name: Ramachandran, Purvaja
name: Ramachandran, Ramesh
name: Sachithanandam, V.
name: Muthukumaran, Jayaraman
name: Singh, Amit Kumar
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences
subject: Virology

description: SARS-CoV-2, a member of beta coronaviruses, is a single-stranded, positive-sense RNA virus responsible for the COVID-19 pandemic. With global fatalities of the pandemic exceeding 4.57 million, it becomes crucial to identify effective therapeutics against the virus. A protease, 3CLpro, is responsible for the proteolysis of viral polypeptides into functional proteins, which is essential for viral pathogenesis. This indispensable activity of 3CLpro makes it an attractive target for inhibition studies. The current study aimed to identify potential lead molecules against 3CLpro of SARS-CoV-2 using a manually curated in-house library of antiviral compounds from mangrove plants. This study employed the structure-based virtual screening technique to evaluate an in-house library of antiviral compounds against 3CLpro of SARS-CoV-2. The library was comprised of thirty-three experimentally proven antiviral molecules extracted from different species of tropical mangrove plants. The molecules in the library were virtually screened using AutoDock Vina, and subsequently, the top five promising 3CLpro-ligand complexes along with 3CLpro-N3 (control molecule) complex were subjected to MD simulations to comprehend their dynamic behaviour and structural stabilities. Finally, the MM/PBSA approach was used to calculate the binding free energies of 3CLpro complexes. Among all the studied compounds, Catechin achieved the most significant binding free energy (−40.3 ± 3.1 kcal/mol), and was closest to the control molecule (−42.8 ± 5.1 kcal/mol), and its complex with 3CLpro exhibited the highest structural stability. Through extensive computational investigations, we propose Catechin as a potential therapeutic agent against SARS-CoV-2. Communicated by Ramaswamy H. Sarma
A murine model for neuropsychiatric disorders associated with group A Î²-hemolytic streptococcal infection
Creators: name: Hoffman, Kurt L.
name: Hornig, Mady
name: Yaddanapudi, Kavitha
name: Jabado, Omar J.
name: Lipkin, W. Ian
Publisher: name: Columbia University
Year: 2004
Subjects: Epidemiology
Virology

description: A syndrome of motoric and neuropsychiatric symptoms comprising various elements, including chorea, hyperactivity, tics, emotional lability, and obsessive-compulsive symptoms, can occur in association with group A Î²-hemolytic streptococcal (GABHS) infection. We tested the hypothesis that an immune response to GABHS can result in behavioral abnormalities. Female SJL/J mice were immunized and boosted with a GABHS homogenate in Freund's adjuvant, whereas controls received Freund's adjuvant alone. When sera from GABHS-immunized mice were tested for immunoreactivity to mouse brain, a subset was found to be immunoreactive to several brain regions, including deep cerebellar nuclei (DCN), globus pallidus, and thalamus. GABHS-immunized mice having serum immunoreactivity to DCN also had increased IgG deposits in DCN and exhibited increased rearing behavior in open-field and hole-board tests compared with controls and with GABHS-immunized mice lacking serum anti-DCN antibodies. Rearing and ambulatory behavior were correlated with IgG deposits in the DCN and with serum immunoreactivity to GABHS proteins in Western blot. In addition, serum from a GABHS mouse reacted with normal mouse cerebellum in nondenaturing Western blots and immunoprecipitated C4 complement protein and Î±-2-macroglobulin. These results are consistent with the hypothesis that immune response to GABHS can result in motoric and behavioral disturbances and suggest that anti-GABHS antibodies cross-reactive with brain components may play a role in their pathophysiology.
Hock injuries in freestall housed dairy cows
Creators: name: Barrientos Araneda, Alejandra Karina
Publisher: name: University of British Columbia
Year: 2013

description: The objective of this thesis was to investigate housing and management risk factors associated with the prevalence of hock injuries in freestall herds (n = 76) in two areas of intensive dairy production, Northeastern US (NE-US) and California (CA). One group of high-production multiparous cows (n = 38) was monitored for hock injuries on each farm and data on management, facility and stall design were collected. Risk factors associated with the overall proportion of cows having injuries or severe injuries at the univariable level were submitted to multivariable general linear models. In NE-US, overall hock injuries increased with the percentage of stalls with fecal contamination (OR = 1.26; CI = 1.02 to 1.54, for a 10% increase), and with the use of sawdust bedding (OR = 3.47; CI = 1.14 to 10.62), and decreased with deep bedding (OR = 0.05; CI = 0.02 to 0.14), sand bedding (OR = 0.06; CI = 0.02 to 0.15), bedding DM ≥ 83.9% (OR = 0.08; CI = 0.03 to 0.20), and access to pasture during the dry period (OR = 0.17; CI = 0.05 to 0.53). In the multivariable model, only the presence of deep bedding remained significant. Severe hock injuries increased with the use of automatic scrapers (OR = 2.29; CI = 1.11 to 4.71) and the percentage of stalls with fecal contamination (OR = 1.14; CI = 1.00 to 1.31, for a 10% increase), and decreased with sand bedding (OR = 0.22; CI = 0.10 to 0.49), deep bedding (OR = 0.24; CI = 0.11 to 0.52), bedding DM ≥ 83.9% (OR = 0.28; CI = 0.14 to 0.58), and access to pasture during the dry period (OR = 0.42; CI = 0.18 to 0.97). The multivariable model included the use of automatic scrapers and deep bedding. In CA, stall stocking density (OR = 1.41; CI = 1.00 to 2.01, for a 10% increase) and bedding concavity (OR = 1.08; CI = 1.01 to 1.16, for a 2.5-cm decrease) were associated with an increase of hock injuries. In general, deep-bedded and well-maintained stalls significantly reduced the risk of hock injuries.
Inferential models: A framework for prior-free posterior probabilistic inference
Creators: name: Martin, Ryan
name: Liu, Chuanhai
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistics Theory (math.ST)
subject: Methodology (stat.ME)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: Posterior probabilistic statistical inference without priors is an important but so far elusive goal. Fisher's fiducial inference, Dempster-Shafer theory of belief functions, and Bayesian inference with default priors are attempts to achieve this goal but, to date, none has given a completely satisfactory picture. This paper presents a new framework for probabilistic inference, based on inferential models (IMs), which not only provides data-dependent probabilistic measures of uncertainty about the unknown parameter, but does so with an automatic long-run frequency calibration property. The key to this new approach is the identification of an unobservable auxiliary variable associated with observable data and unknown parameter, and the prediction of this auxiliary variable with a random set before conditioning on data. Here we present a three-step IM construction, and prove a frequency-calibration property of the IM's belief function under mild conditions. A corresponding optimality theory is developed, which helps to resolve the non-uniqueness issue. Several examples are presented to illustrate this new approach.
description: 29 pages with 3 figures. Main text is the same as the published version. Appendix B is an addition, not in the published version, that contains some corrections and extensions of two of the main theorems
Functional near-infrared spectrometry for auditory speech stimuli in cochlear implant users: a systematic literature review
Creators: name: Gomes, Larissa Fernandes
name: de Vasconcelos, Isabelle Costa
name: Taveira, Karinna Veríssimo Meira
name: Balen, Sheila Andreoli
name: Brazorotto, Joseli Soares
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: This study aims to identify the acquisition features of functional near-infrared spectroscopy (fNIRS) in cochlear implant users. A systematic literature review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, EMBASE, LILACS, Web of Science, Scopus, PsycINFO, IEEE Xplore, Google Scholar, and ProQuest Dissertations & Theses Global were searched using the PECOS acronym. Inclusion criteria encompassed studies involving fNIRS with speech stimuli in cochlear implant users of any age, with information on acquisition parameters and features. Risk of bias assessment was performed using the Joanna Briggs Institute tool. Nineteen studies were included, with thirteen exhibiting a low risk of bias. Noteworthy uniformity was observed in certain fNIRS acquisition features among cochlear implant users, including the waking state (awake), auditory stimuli of words or phrases presented in a free field, visual stimuli displayed during data collection as a secondary task, recording of responses in the bilateral temporal lobe, and a three-centimeter distance between optodes. Variations in acquisition were attributed to differing study purposes. This review identifies common acquisition characteristics for fNIRS in cochlear implant users. Multicenter research efforts are advocated to further advance the utility of fNIRS in this population.
Discovery and molecular characterization of West Nile virus NY 1999
Creators: name: Jordan, Ingo
name: Briese, Thomas
name: Lipkin, W. Ian
Publisher: name: Columbia University
Year: 2000
Subjects: Epidemiology
Virology
West Nile virus
Communicable diseases

description: An account of the 1999 outbreak of West Nile virus infections in New York City.
Assessment of polymicrobial infections in ticks in New York State
Creators: name: Tokarz, Rafal
name: Jain, Komal
name: Bennett, Ashlee
name: Briese, Thomas
name: Lipkin, W. Ian
Publisher: name: Columbia University
Year: 2010
Subjects: Epidemiology
Virology
Ticks
Ticks as carriers of disease

description: Ixodes scapularis ticks are clinically important hematophagous vectors. A single tick bite can lead to a polymicrobial infection. We determined the prevalence of polymicrobial infection with Borrelia burgdorferi, Anaplasma phagocytophilum, Babesia microti, Borrelia miyamotoi, and Powassan virus in 286 adult ticks from the two counties in New York State where Lyme disease is endemic, utilizing a MassTag multiplex polymerase chain reaction assay. Seventy-one percent of the ticks harbored at least one organism; 30% had a polymicrobial infection. Infections with three microbes were detected in 5% of the ticks. One tick was infected with four organisms. Our results show that coinfection is a frequent occurrence in ticks in the two counties surveyed.
ART^2 : Coupling Lyman-alpha Line and Multi-wavelength Continuum Radiative Transfer
Creators: name: Yajima, Hidenobu
name: Li, Yuexing
name: Zhu, Qirong
name: Abel, Tom
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Narrow-band Lya line and broad-band continuum have played important roles in the discovery of high-redshift galaxies in recent years. Hence, it is crucial to study the radiative transfer of both Lya and continuum photons in the context of galaxy formation and evolution in order to understand the nature of distant galaxies. Here, we present a three-dimensional Monte Carlo radiative transfer code, All-wavelength Radiative Transfer with Adaptive Refinement Tree (ART^2), which couples Lya line and multi-wavelength continuum, for the study of panchromatic properties of galaxies and interstellar medium. This code is based on the original version of Li et al., and features three essential modules: continuum emission from X-ray to radio, Lya emission from both recombination and collisional excitation, and ionization of neutral hydrogen. The coupling of these three modules, together with an adaptive refinement grid, enables a self-consistent and accurate calculation of the Lya properties. As an example, we apply ART^2 to a cosmological simulation that includes both star formation and black hole growth, and study in detail a sample of massive galaxies at redshifts z=3.1 - 10.2. We find that these galaxies are Lya emitters (LAEs), whose Lya emission traces the dense gas region, and that their Lya lines show a shape characteristic of gas inflow. Furthermore, the Lya properties, including photon escape fraction, emergent luminosity, and equivalent width, change with time and environment. Our results suggest that LAEs evolve with redshift, and that early LAEs such as the most distant one detected at z ~ 8.6 may be dwarf galaxies with a high star formation rate fueled by infall of cold gas, and a low Lya escape fraction.
description: 20 pages, 16 figures, accepted for publication in MNRAS
Switching the reflection in chiral nematic mesoporous silica and organosilica films
Creators: name: De Witt, Joanna Christine
Publisher: name: University of British Columbia
Year: 2013

description: Recently, a new class of free-standing chiral nematic mesoporous silica and organosilica films was developed using nanocrystalline cellulose as a template. Due to their unique structures these films are iridescent, and by varying synthetic conditions it has been shown that this iridescence can be tuned to selectively reflect incident light of different wavelengths across the entire visible spectrum. However, upon formation of the mesostructure, these optical properties are locked in and can no longer be altered. Herein I describe alternate techniques to modify the optical properties of these silica and organosilica films by infiltration with guest molecules after the films have been prepared. Liquid crystal mesogen 5CB and 8CB were loaded into the pores of unfunctionalized and octyl and phenyl functionalized silica films. Thermal cycling of these new composite materials elucidated a sharp and reversible optical change in the 8CB loaded octyl functionalized silica films. Additional studies including variable temperature POM and UV-Vis spectroscopy were conducted on this system prepared with organosilica films. This approach was then expanded on by doping an azobenzene derivative in 1, 5, and 10 % by weight into the 8CB liquid crystal before loading the mixtures into the films. A reversible optical change was then brought about in this system by irradiation at different wavelengths. Further development of these methods could lead to their implementation in the still emerging fields of sensing and display technologies involving colour information.
Progressive hearing loss in childhood – shifting from reactive to dynamic management
Creators: name: Dempsey, James
name: Kort, Karolina Kluk-De
name: Bruce, Iain A
name: Nichani, Jaya
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Advances in worn and implantable hearing device technology is such that hearing can now be successfully (re)habilitated from mild to profound hearing loss. Whilst hearing services have access to the latest digital hearing devices, bone conduction and cochlear implants, two main research and clinical challenges remain within the pediatric population, namely matching the device to the hearing loss and needs of the individual (e.g. borderline cochlear implant candidacy), and early identification to facilitate timely intervention across the pediatric life span. Deteriorating and later-onset hearing loss are exemplars of the challenges faced.
Genomic and phylogenetic characterization of Merino Walk virus, a novel arenavirus isolated in South Africa
Creators: name: Palacios, Gustavo F.
name: Savji, Nazir
name: Hui, Jeffrey
name: Da Rosa, Amelia Travassos
name: Popov, Vsevolod
name: Briese, Thomas
name: Tesh, Robert
name: Lipkin, W. Ian
Publisher: name: Columbia University
Year: 2010
Subjects: Epidemiology
Virology

description: Merino Walk virus (MWV), a proposed novel tentative species of the family Arenaviridae, was isolated from a rodent, Myotomys unisulcatus, collected at Merino Walk, Eastern Cape, South Africa, in 1985. Full-length genomic sequence confirmed MWV as an arenavirus related distantly to Mobala, Mopeia and Ippy viruses, all members of the Old World arenavirus complex. We propose MWV as a tentative novel species in the Lassaâ€“lymphocytic choriomeningitis virus complex, based on its isolation from a novel rodent species and its genetic and serological characteristics.
$J/ψ$ reaction mechanisms and suppression in the nuclear medium
Creators: name: Molina, R.
name: Xiao, C. W.
name: Oset, E.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Recent studies of the interaction of vector mesons with nuclei make possible and opportune the study of the interaction of the $J/ψ$ with nuclei and the investigation of the origin of the $J/ψ$ suppression in its propagation thorough a nuclear medium. We observe that the transition of $J/ψN$ to $VN$ with $V$ being a light vector, $ρ, ω,ϕ$, together with the inelastic channels, $J/ψN \to \bar D Λ_c$ and $J/ψN \to \bar D Σ_c$ leads to a particular shape of the inelastic cross section. Analogously, we consider the mechanisms where the exchanged $D$ collides with a nucleon and gives $πΛ_c$ or $πΣ_c$. The cross section has a peak around $\sqrt s=4415$ MeV, where the $J/ψN$ couples to a resonance predicted recently. We study the transparency ratio for electron induced $J/ψ$ production in nuclei at about 10 GeV and find that 30 - 35% of the $J/ψ$ produced in heavy nuclei are absorbed inside the nucleus. This ratio is in line with depletions of $J/ψ$ though matter observed in other reactions.
description: 17 pages, 11 figures, this is the new version after replacement action
Authentic Borna disease virus transcripts are spliced less efficiently than cDNA-derived viral RNAs
Creators: name: Jehle, Christian
name: Lipkin, W. Ian
name: Staeheli, Peter
name: Marion, Rosa M.
name: Schwemmle, Martin
Publisher: name: Columbia University
Year: 2000
Subjects: Epidemiology
Virology

description: Borna disease virus (BDV) is a non-segmented, negative-strand RNA virus that replicates and transcribes its genome in the nucleus of infected cells. It uses the cellular splicing machinery to generate a set of alternatively spliced mRNAs from the 2.8 and 7.1 kb primary transcripts, each harbouring two introns. To determine whether splicing of these transcripts is regulated by viral factors, the extent of splicing was studied in infected cells and COS-7 cells transiently transfected with plasmids encoding the 2.8 kb RNA of BDV. Unspliced RNA was found to be the most abundant RNA species in infected cells, whereas viral transcripts lacking both introns were only found in minute amounts. In sharp contrast, plasmid-derived 2.8 kb RNA was predominantly intron 1-spliced and double-spliced. Co-expression of the BDV proteins P, N and X did not influence splicing of plasmid-expressed 2.8 kb RNA. Furthermore, the splicing pattern did not change when the 2.8 kb RNA was expressed in BDV-infected cells. Based on these results we speculate that splicing of authentic BDV transcripts is tightly linked to transcription by the viral polymerase.
Fractional topological phases and broken time reversal symmetry in strained graphene
Creators: name: Ghaemi, P.
name: Cayssol, J.
name: Sheng, D. N.
name: Vishwanath, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We show that strained or deformed honeycomb lattices are promising platforms to realize fractional topological quantum states in the absence of any magnetic field. The strained induced pseudo magnetic fields are oppositely oriented in the two valleys [1-3] and can be as large as 60-300 Tesla as reported in recent experiments [4,5]. For strained graphene at neutrality, a spin or a valley polarized state is predicted depending on the value of the onsite Coulomb interaction. At fractional filling, the unscreened Coulomb interaction leads to a valley polarized Fractional Quantum Hall liquid which spontaneously breaks time reversal symmetry. Motivated by artificial graphene systems [5-8], we consider tuning the short range part of interactions, and demonstrate that exotic valley symmetric states, including a valley Fractional Topological Insulator and a spin triplet superconductor, can be stabilized by such interaction engineering.
description: 5 pages + supplementary, 4 figures. Version accepted to Physical Review Letters
Spatiotemporal dynamics of evapotranspiration in the Yellow River Basin: implications of climate variability and land use change
Creators: name: Khan, Sheheryar
name: Wang, Huiliang
name: Boota, Muhammad Waseem
name: Nauman, Umer
name: Muhammad, Ali
name: Wu, Zening
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: The Yellow River Basin (YRB) has experienced substantial fluctuations in climate and alterations in land use and land cover change (LUCC). Hence, our research aims to examine the impact of climate change and LUCC on surface evapotranspiration (ET) during the period 2000 to 2020. The data are obtained from MODIS products in comparison with water balance model. The study examined the correlation between ET and meteorological parameters, including precipitation (Pr), temperature (Temp), relative humidity (Rh), wind speed (U10) and net radiation (Rn), using the CHIRPS, ERA5 and FLDAS datasets. The Theil-Sen slope estimator and Mann-Kendall (M-K) test were utilized to assess the amplitude and statistical significance of trends in ET. The study thoroughly examined the annual and seasonal patterns. The yearly mean ET of 568.2 mm increased by approximately 11.43% and 7.30% during growing season. The recorded figure of 485.6 mm for the summer is significantly elevated, linked to higher Temp and U10. With hike of 21.06% in spring and urbanization from 242,749.5 km2 to 463,351.7 km2, although 1,595,073.5 km2 remained croplands, Rh and Pr have a strong negative association with ET (r = −0.747) and (r = −0.718), respectively. Meteorological factors have a diverse effect as Rn, Temp and U10 increase ET, while Pr and humidity decrease ET.
Additional file 3: of Exploration of exosomal microRNA expression profiles in pigeon ‘Milk’ during the lactation period
Creators: name: Ma, Yao
name: Feng, Siyuan
name: Wang, Xun
name: Qazi, Izhar
name: Long, Keren
name: Luo, Yi
name: Li, Guojun
name: Ning, Chunyou
name: Wang, Yixin
name: Hu, Silu
name: Xiao, Juan
name: Li, Xiaokai
name: Lan, Dan
name: Hu, Yaodong
name: Tang, Qianzi
name: Ma, Jideng
name: Jin, Long
name: Jiang, Anan
name: Li, Mingzhou
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Figure S2. Length distribution and expression distribution of identified exosomal miRNAs in PM. (PDF 396 kb)
Subjects or objects? prisoners and human experimentation
Creators: name: Lerner, Barron H.
Publisher: name: Columbia University
Year: 2007
Subjects: Medical ethics

description: During the 1950s, inmates at what was then called Holmesburg Prison, in Philadelphia, were inoculated with condyloma acuminatum, cutaneous moniliasis, and viruses causing warts, herpes simplex, and herpes zoster. For participating in this research, and in studies exposing them to dioxin and agents of chemical warfare, they were paid up to $1,500 a month. Between 1963 and 1971, researchers in Oregon and Washington irradiated and repeatedly took biopsy specimens from the testicles of healthy prisoners; the men subsequently reported rashes, peeling, and blisters on the scrotum as well as sexual difficulties. Hundreds of such experiments induced the federal government to essentially ban research involving prisoners in 1978. The message: such research is fundamentally exploitative and thus unethical. Yet a recent report by the Institute of Medicine (IOM) has opened the closed door, arguing not only that such research can be performed appropriately but that prisoners deserve to be included in investigative studies — at least those who might benefit directly. Examination of the explanations behind U.S. restrictions on prison research and their current applicability can provide guidance for today's policy debates.
Light convolutional neural network by neural architecture search and model pruning for bearing fault diagnosis and remaining useful life prediction
Creators: name: Ruan, Diwang
name: Han, Jinzhao
name: Yan, Jianping
name: Gühmann, Clemens
Publisher: name: Springer Science and Business Media LLC
Year: 2023
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::620 Ingenieurwissenschaften::620 Ingenieurwissenschaften und zugeordnete Tätigkeiten
subject: electrical engineering
subject: electronic engineering
subject: mechanical engineering

description: Convolutional Neural Network (CNN) has been extensively used in bearing fault diagnosis and Remaining Useful Life (RUL) prediction. However, accompanied by CNN’s increasing performance is a deeper network structure and growing parameter size. This prevents it from being deployed in industrial applications with limited computation resources. To this end, this paper proposed a two-step method to build a cell-based light CNN by Neural Architecture Search (NAS) and weights-ranking-based model pruning. In the first step, a cell-based CNN was constructed with searched optimal cells and the number of stacking cells was limited to reduce the network size after influence analysis. To search for the optimal cells, a base CNN model with stacking cells was initially built, and Differentiable Architecture Search was adopted after continuous relaxation. In the second step, the connections in the built cell-based CNN were further reduced by weights-ranking-based pruning. Experiment data from the Case Western Reserve University was used for validation under the task of fault classification. Results showed that the CNN with only two cells achieved a test accuracy of 99.969% and kept at 99.968% even if 50% connections were removed. Furthermore, compared with base CNN, the parameter size of the 2-cells CNN was reduced from 9.677MB to 0.197MB. Finally, after minor revision, the network structure was adapted to achieve bearing RUL prediction and validated with the PRONOSTIA test data. Both tasks confirmed the feasibility and superiority of constructing a light cell-based CNN with NAS and pruning, which laid the potential to realize a light CNN in embedded systems.
Public health policy and the AIDS epidemic : an end to HIV exceptionalism?
Creators: name: Bayer, Ronald
Publisher: name: Columbia University
Year: 1991
Subjects: Public health

description: In the early and mid-1980s, when democratic nations were forced to confront the public health challenge posed by the epidemic of the acquired immunodeficiency syndrome (AIDS), it was necessary to face a set of fundamental questions: Did the history of responses to lethal infectious diseases provide lessons about how best to contain the spread of human immunodeficiency virus (HIV) infection? Should the policies developed to control sexually transmitted diseases or other communicable conditions be applied to AIDS? If AIDS were not to be so treated, what would justify such differential policies?
title: Eleonore von Braunschweig-Lüneburg-Celle
title: An entry in the LCA Online Dictionary of Leibniz’s Correspondents and Acquaintances
titleType: Subtitle
Creators: name: (:Tba)
Publisher: name: LCA Project
Year: 2018

description: Eleonore von Braunschweig-Lüneburg-Celle as a personal relation of Leibniz’s: The resource presents biographical information on a correspondent of Leibniz's
Deformations of extremal toric manifolds
Creators: name: Rollin, Yann
name: Tipler, Carl
Publisher: name: arXiv
Year: 2012
Subjects: subject: Differential Geometry (math.DG)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 53C55 (Primary) 14M25 (Secondary)

description: Let $X$ be a compact toric extremal Kähler manifold. Using the work of Székelyhidi, we provide a combinatorial criterion on the fan describing $X$ to ensure the existence of complex deformations of $X$ that carry extremal metrics. As an example, we find new CSC metrics on 4-points blow-ups of $\C¶^1\times\C¶^1$.
description: 25 pages, 9 figures, final version, to appear in JGA
Statistical Description of Hydrodynamic Processes in Ionic Melts with taking into account Polarization Effects
Creators: name: Markiv, B.
name: Vasylenko, A.
name: Tokarchuk, M.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Statistical description of hydrodynamic processes for ionic melts is proposed with taking into account polarization effects caused by the deformation of external ionic shells. This description is carried out by means of the Zubarev nonequilibrium statistical operator method, appropriate for investigations of both strong and weak nonequilibrium processes. The nonequilibrium statistical operator and the generalized hydrodynamic equations that take into account polarization processes are received for ionic-polarization model of ionic molten salts when the nonequilibrium averaged values of densities of ions number, their momentum, dipole momentum and total energy are chosen for the reduced description parameters. A spectrum of collective excitations is investigated within the viscoelastic approximation for ion-polarization model of ionic melts.
description: 24 pages, RevTex4.1-format, no figures
Lack of association between measles virus vaccine and autism with enteropathy : a case-control study
Creators: name: Hornig, Mady
name: Briese, Thomas
name: Buie, Timothy
name: Bauman, Margaret L.
name: Lauwers, Gregory
name: Siemetzki, Ulrike
name: Hummel, Kimberly
name: Rota, Paul A.
name: Bellini, William J.
name: O'Leary, John J.
name: Sheils, Orla
name: Alden, Errol
name: Pickering, Larry
name: Lipkin, W. Ian
Publisher: name: Columbia University
Year: 2008
Subjects: Epidemiology
Virology
Measles--Vaccination
Autism spectrum disorders

description: The presence of measles virus (MV) RNA in bowel tissue from children with autism spectrum disorders (ASD) and gastrointestinal (GI) disturbances was reported in 1998. Subsequent investigations found no associations between MV exposure and ASD but did not test for the presence of MV RNA in bowel or focus on children with ASD and GI disturbances. Failure to replicate the original study design may contribute to continued public concern with respect to the safety of the measles, mumps, and rubella (MMR) vaccine. The objective of this case-control study was to determine whether children with GI disturbances and autism are more likely than children with GI disturbances alone to have MV RNA and/or inflammation in bowel tissues and if autism and/or GI episode onset relate temporally to receipt of MMR. The sample was an age-matched group of US children undergoing clinically-indicated ileocolonoscopy. Ileal and cecal tissues from 25 children with autism and GI disturbances and 13 children with GI disturbances alone (controls) were evaluated by real-time reverse transcription (RT)-PCR for presence of MV RNA in three laboratories blinded to diagnosis, including one wherein the original findings suggesting a link between MV and ASD were reported. The temporal order of onset of GI episodes and autism relative to timing of MMR administration was examined. We found no differences between case and control groups in the presence of MV RNA in ileum and cecum. Results were consistent across the three laboratory sites. GI symptom and autism onset were unrelated to MMR timing. Eighty-eight percent of ASD cases had behavioral regression. This study provides strong evidence against association of autism with persistent MV RNA in the GI tract or MMR exposure. Autism with GI disturbances is associated with elevated rates of regression in language or other skills and may represent an endophenotype distinct from other ASD.
U^p-Net: a generic deep learning-based time stepper for parameterized spatio-temporal dynamics
Creators: name: Stender, Merten
name: Ohlsen, Jakob
name: Geisler, Hendrik
name: Chabchoub, Amin
name: Hoffmann, Norbert
name: Schlaefer, Alexander
Publisher: name: Springer Science and Business Media LLC
Year: 2023
Subjects: subject: 000 Informatik, Informationswissenschaft, allgemeine Werke::000 Informatik, Wissen, Systeme::004 Datenverarbeitung; Informatik
subject: partial differential equations
subject: machine learning
subject: wave propagation
subject: representation learning
subject: time integration
subject: sensor data fusion

description: In the age of big data availability, data-driven techniques have been proposed recently to compute the time evolution of spatio-temporal dynamics. Depending on the required a priori knowledge about the underlying processes, a spectrum of black-box end-to-end learning approaches, physics-informed neural networks, and data-informed discrepancy modeling approaches can be identified. In this work, we propose a purely data-driven approach that uses fully convolutional neural networks to learn spatio-temporal dynamics directly from parameterized datasets of linear spatio-temporal processes. The parameterization allows for data fusion of field quantities, domain shapes, and boundary conditions in the proposed U^p-Net architecture. Multi-domain U^p-Net models, therefore, can generalize to different scenes, initial conditions, domain shapes, and domain sizes without requiring re-training or physical priors. Numerical experiments conducted on a universal and two-dimensional wave equation and the transient heat equation for validation purposes show that the proposed U^p-Net outperforms classical U-Net and conventional encoder–decoder architectures of the same complexity. Owing to the scene parameterization, the U^p-Net models learn to predict refraction and reflections arising from domain inhomogeneities and boundaries. Generalization properties of the model outside the physical training parameter distributions and for unseen domain shapes are analyzed. The deep learning flow map models are employed for long-term predictions in a recursive time-stepping scheme, indicating the potential for data-driven forecasting tasks. This work is accompanied by an open-sourced code.
Genetic and epidemiological characterization of Stretch Lagoon orbivirus, a novel orbivirus isolated from Culex and Aedes mosquitoes in northern Australia
Creators: name: Cowled, Chris
name: Palacios, Gustavo F.
name: Melville, Lorna
name: Weir, Richard
name: Walsh, Susan
name: Davis, Steven
name: Gubala, Aneta
name: Lipkin, W. Ian
name: Briese, Thomas
name: Boyle, David
Publisher: name: Columbia University
Year: 2009
Subjects: Epidemiology
Virology

description: Stretch Lagoon orbivirus (SLOV) was isolated in 2002 from pooled Culex annulirostris mosquitoes collected at Stretch Lagoon, near the Wolfe Creek national park in the Kimberley region of Western Australia. Conventional serological tests were unable to identify the isolate, and electron microscopy indicated a virus of the genus Orbivirus, family Reoviridae. Here, a cDNA subtraction method was used to obtain approximately one-third of the viral genome, and further sequencing was performed to complete the sequences of segment 1 (viral polymerase) and segment 2 (conserved inner-core protein). Phylogenetic analysis showed that SLOV should be considered a new species within the genus Orbivirus. A real-time RT-PCR test was designed to study the epidemiology of SLOV in the field. Six additional isolates of SLOV were identified, including isolates from four additional locations and two additional mosquito species. Horses, donkeys and goats were implicated as potential vertebrate hosts in a serological survey.
Additional file 4: of Driving following defibrillator implantation: development and pilot results from a nationwide questionnaire
Creators: name: Bjerre, Jenny
name: Rosenkranz, Simone
name: Christensen, Anne
name: Schou, Morten
name: JĂ¸ns, Christian
name: Gislason, Gunnar
name: Ruwald, Anne-Christine
Publisher: name: figshare
Year: 2018
Subjects: Space Science
Medicine
Biological Sciences not elsewhere classified
Developmental Biology
Science Policy
Computational Biology

description: Table S3. Test-Retest Agreement. (DOCX 19 kb)
title: Elisabeth von der Pfalz
title: An entry in the LCA Online Dictionary of Leibniz’s Correspondents and Acquaintances
titleType: Subtitle
Creators: name: (:Tba)
Publisher: name: LCA Project
Year: 2018

description: Elisabeth von der Pfalz as a personal relation of Leibniz’s: The resource presents biographical information on a correspondent of Leibniz's
Order in a Spatially Anisotropic Triangular Antiferromagnet
Creators: name: Ghamari, Sedigh
name: Kallin, Catherine
name: Lee, Sung-Sik
name: Sørensen, Erik S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The phase diagram of the spin-1/2 Heisenberg antiferromagnet on an anisotropic triangular lattice of weakly coupled chains, a model relevant to Cs2CuCl4, is investigated using a renormalization group analysis, which includes marginal couplings important for connecting to numerical studies of this model. In particular, the relative stability of incommensurate spiral spin-density order and collinear antiferromagnetic order is studied. While incommensurate spiral order is found to exist over most of the phase diagram in the presence of a Dzyaloshinskii-Moriya (DM) interaction, at small interchain and extremely weak DM couplings, collinear antiferromagnetic order can survive. Our results imply that Cs2CuCl4 is well within the part of the phase diagram where spiral order is stable. The implications of the renormalization group analysis for numerical studies, many of which have found spin-liquidlike behavior, are discussed.
description: 10 pages, 7 figures, minor edits and reference added