cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Performance of cryogenic charge readout electronics with the ARGONTUBE LAr TPC
Creators: name: Ereditato, A.
name: Goeldi, D.
name: Janos, S.
name: Kreslo, I.
name: Luethi, M.
name: von Rohr, C. Rudolf
name: Schenk, M.
name: Strauss, T.
name: Weber, M. S.
name: Zeller, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: ARGONTUBE is a liquid argon time projection chamber (TPC) with an electron drift length of up to 5 m equipped with cryogenic charge-sensitive preamplifiers. In this work, we present results on its performance including a comparison of the new cryogenic charge-sensitive preamplifiers with the previously used room-temperature-operated charge preamplifiers.
Observational insights on the formation scenarios of giant low surface brightness galaxies
Creators: name: Saburova, Anna
name: Chilingarian, Igor
name: Kasparova, Anastasia
name: Sil'chenko, Olga
name: Katkov, Ivan
name: Grishin, Kirill
name: Uklein, Roman
Publisher: name: arXiv
Year: 2021
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Giant low surface brightness galaxies (gLSBGs) with the disk radii of up to 130 kpc represent a challenge for currently accepted theories of galaxy formation and evolution, because it is difficult to build-up such large dynamically cold systems via mergers preserving extended disks. We summarize the in-depth study of the sample of 7 gLSBGs based on the results of the performed spectral long-slit observations at the Russian 6-m BTA telescope of SAO RAS, surface photometry and HI data available in literature. Our study revealed that most gLSBGs do not deviate from the Tully-Fisher relation. We discovered compact elliptical (cE) satellites in 2 out of these 7 galaxies. Provided the low statistical frequencies of gLSBGs and cEs, the chance alignment is improbable, so it can indicate that gLSBGs and cE are evolutionary connected and gives evidence in favor of the major merger formation scenario. Other formation paths of gLSBGs are also discussed.
description: 5 pages, 1 figure. Astronomy at the epoch of multimessenger studies. Proceedings of the VAK-2021 conference, Aug 23-28, 2021 - Moscow, 2021
On the Kähler-Hodge structure of superconformal manifolds
Creators: name: Niarchos, Vasilis
name: Papadodimas, Kyriakos
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We show that conformal manifolds in $d\geq 3$ conformal field theories with at least 4 supercharges are Kähler-Hodge, thus extending to 3d ${\cal N}=2$ and 4d ${\cal N}=1$ similar results previously derived for 4d ${\cal N}=2$ and ${\cal N}=4$ and various types of 2d SCFTs. Conformal manifolds in SCFTs are equipped with a holomorphic line bundle ${\cal L}$, which encodes the operator mixing of supercharges under marginal deformations. Using conformal perturbation theory and superconformal Ward identities, we compute the curvature of ${\cal L}$ at a generic point on the conformal manifold. We show that the Kähler form of the Zamolodchikov metric is proportional to the first Chern class of ${\cal L}$, with a constant of proportionality given by the two-point function coefficient of the stress tensor, $C_T$. In cases where certain additional conditions about the nature of singular points on the conformal manifold hold, this implies a quantization condition for the total volume of the conformal manifold.
description: 33 pages, typos corrected
Optomechanical Raman-Ratio Thermometry
Creators: name: Purdy, T. P.
name: Yu, P. -L.
name: Kampel, N. S.
name: Peterson, R. W.
name: Cicak, K.
name: Simmonds, R. W.
name: Regal, C. A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The temperature dependence of the asymmetry between Stokes and anti-Stokes Raman scattering can be exploited for self-calibrating, optically-based thermometry. In the context of cavity optomechanics, we observe the cavity-enhanced scattering of light interacting with the standing-wave drumhead modes of a silicon nitride membrane mechanical resonator. The ratio of the amplitude of Stokes to anti-Stokes scattered light is used to measure temperatures of optically-cooled mechanical modes down to the level of a few vibrational quanta. We demonstrate that the Raman-ratio technique is able to measure the physical temperature of our device over a range extending from cryogenic temperatures to within an order of magnitude of room temperature.
description: 5 pages, 4 figures
Do crystal structures obviate the need for theoretical models of GPCRs for structure-based virtual screening?
Creators: name: Hsieh, Jui-Hua
name: Tang, Hao
name: Wang, Xiang Simon
name: Tropsha, Alexander
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Recent highly expected structural characterizations of agonist-bound and antagonist-bound beta-2 adrenoreceptor (β2AR) by X-ray crystallography have been widely regarded as critical advances to enable more effective structure-based discovery of GPCRs ligands. It appears that this very important development may have undermined many previous efforts to develop 3D theoretical models of GPCRs. To address this question directly we have compared several historical β2AR models versus the inactive state and nanobody-stabilized active state of β2AR crystal structures in terms of their structural similarity and effectiveness of use in virtual screening for β2AR specific agonists and antagonists. Theoretical models, incluing both homology and de novo types, were collected from five different groups who have published extensively in the field of GPCRs modeling; all models were built before X-ray structures became available. In general, β2AR theoretical models differ significantly from the crystal structure in terms of TMH definition and the global packing. Nevertheless, surprisingly, several models afforded hit rates resulting from virtual screening of large chemical library enriched by known β2AR ligands that exceeded those using X-ray structures; the hit rates were particularly higher for agonists. Furthemore, the screening performance of models is associated with local structural quality such as the RMSDs for binding pocket residues and the ability to capture accurately most if not all critical protein/ligand interactions. These results suggest that carefully built models of GPCRs could capture critical chemical and structural features of the binding pocket thus may be even more useful for practical structure-based drug discovery than X-ray structures.
Quantitative proteomic analysis of LPS-induced differential immune response associated with TLR4 Polymorphisms by multiplex amino acid coded mass tagging
Creators: name: Gu, Sheng
name: Wang, Tianyi
name: Chen, Xian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Polymorphisms at Toll-like receptor 4 (TLR4) gene have been found to be associated with immune disorders. A murine macrophage cell line GG2EE derived from C3H/HeJ mice with a polymorphism site at TLR4 is hyposensitive to lipopolysacchride (LPS). To study the molecular base of diverse TLR4-mediated immune responses, the proteomic changes in both TLR4-deficient and –wild-type cell lines in response to the same LPS challenge were quantitatively compared by using multiplex amino acid coded mass-tagging (AACT)/SILAC-assisted mass spectrometry (MS). This strategy allows encoding of two distinct cell populations with different stable isotope-tagged lysine residues as the ‘in-spectra’ quantitative markers. In MS analysis of tryptic peptides derived from the equally mixed three cell populations, the lysine-containing peptides originated from two LPS stimulated cell populations can be clearly distinguished by their different mass shifts from the un-stimulated and unlabeled counterpart. The LPS-induced differential protein expression in TLR4 –deficient and –wild-type proteomes were obtained by comparing the intensities of isotopically encoded peptides. Among the more than 900 proteins identified, 35 were found to be deregulated at different levels in these two cell lines stimulated by LPS. This multiplex mass-tagging methodology can be readily extended to other comparative proteomic quantitation of different cell populations.
ACCOUNTING SKILLS FOR SUSTAINABLE DEVELOPMENT OF SMALL AND MEDIUM SCALE ENTERPRISES IN NIGER STATE, NIGERIA
Creators: name: IDRIS, Benuh Adama, Ph.D
Publisher: name: TOP Journal
Year: 2024
Subjects: Accounting Skills, Sustainable Development, Small and Medium Scale Enterprises

description: The need for sustainable development is one of the key driving forces of the rapid changes and numerous challenges in today’s economic world. Also, putting accounting skills in the context of sustainable development is logically possible. This paper, therefore, examined the accounting skills needed by small and medium enterprises (SMEs) for sustainable economic development using Niger State of Nigeria as a focal point. The paper adopted the descriptive research design approach and data were generated from professionals and owners of SMEs in the state through a structured questionnaire. The data analysis was conducted by means of the mean scores and standard deviations of the respondents. The hypotheses were tested using the t-test statistics and the results showed that T-cal. of 2.50 was greater than the T-table value of 1.96 (T-cal. 2.50 > T-table 1.96) at 0.05 level of significance, this implies that the results showed that the owners of SMEs were of different opinions regarding the accounting skills needed by SMEs in Niger State for sustainable development, thereby rejecting Ho1. Also, the T-cal. of 0.97 was less than the T-table of 1.96 (T-cal. 0.97 < T-table 1.96) at 0.05 level of significance in (Ho2). Therefore, Ho2 was not rejected indicating that owners of SMEs were of the same opinion regarding the benefits of acquiring accounting skills. The paper concludes that the acquisition of accounting skills by owners of SMEs is of utmost importance given the numerous contributions that are inherently accruable to owners and operators of SMEs especially in developing nations. The paper recommends that owners of SMEs should endeavour to employ staff that has basic accounting skills
Accurate quantitation of standard peptides used for quantitative proteomics
Creators: name: Collins, Leonard B.
name: Boysen, Gunnar
name: Cross, Tyra J.
name: Borchers, Christoph H.
name: Georgieva, Nadia I.
name: Bordeerat, Narisa K.
name: Swenberg, James A.
name: Klapper, David G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: MS-based proteomics has become an indispensable tool in system biology generating a need for accurate and precise quantitation of peptide standards. The presented method utilizes ultra performance LC-MS/MS (UPLC-MS/MS) to accurately quantify peptide standards at concentrations of 0.1-10 microM. The ability for accurate quantitation of micro-molar concentrations has the advantages that quantitation can be performed routinely with high precision and the high sensitivity of the method minimizes the amounts required.
Clustering-based Redshift Estimation: Comparison to Spectroscopic Redshifts
Creators: name: Rahman, Mubdi
name: Ménard, Brice
name: Scranton, Ryan
name: Schmidt, Samuel J.
name: Morrison, Christopher B.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We investigate the potential and accuracy of clustering-based redshift estimation using the method proposed by Ménard et al. (2013). This technique enables the inference of redshift distributions from measurements of the spatial clustering of arbitrary sources, using a set of reference objects for which redshifts are known. We apply it to a sample of spectroscopic galaxies from the Sloan Digital Sky Survey and show that, after carefully controlling the sampling efficiency over the sky, we can estimate redshift distributions with high accuracy. Probing the full colour space of the SDSS galaxies, we show that we can recover the corresponding mean redshifts with an accuracy ranging from $δ$z=0.001 to 0.01. We indicate that this mapping can be used to infer the redshift probability distribution of a single galaxy. We show how the lack of information on the galaxy bias limits the accuracy of the inference and show comparisons between clustering redshifts and photometric redshifts for this dataset. This analysis demonstrates, using real data, that clustering-based redshift inference provides a powerful data-driven technique to explore the redshift distribution of arbitrary datasets, without any prior knowledge on the spectral energy distribution of the sources.
description: 13 pages. Submitted to MNRAS. Comments welcome
Parity violation in the scalar trispectrum: no-go theorems and yes-go examples
Creators: name: Cabass, G
name: Jazayeri, S
name: Pajer, E
name: Stefanyszyn, D
Publisher: name: Apollo - University of Cambridge Repository
Year: 2023
Subjects: Regular Article - Theoretical Physics
Early Universe Particle Physics
Effective Field Theories
Space-Time Symmetries

description: Abstract We derive a set of no-go theorems and yes-go examples for the parity-odd primordial trispectrum of curvature perturbations. We work at tree-level in the decoupling limit of the Effective Field Theory of Inflation and assume scale invariance and a Bunch-Davies vacuum. We show that the parity-odd scalar trispectrum vanishes in the presence of any number of scalar fields with arbitrary mass and any parity-odd scalar correlator vanishes in the presence of any number of spinning fields with massless de Sitter mode functions, in agreement with the findings of Liu, Tong, Wang and Xianyu [1]. The same is true for correlators with an odd number of conformally-coupled external fields. We derive these results using both the (boostless) cosmological bootstrap, in particular the Cosmological Optical Theorem, and explicit perturbative calculations. We then discuss a series of yes-go examples by relaxing the above assumptions one at the time. In particular, we provide explicit results for the parity-odd trispectrum for (i) violations of scale invariance in single-clock inflation, (ii) the modified dispersion relation of the ghost condensate (non-Bunch-Davies vacuum), and (iii) interactions with massive spinning fields. Our results establish the parity-odd trispectrum as an exceptionally sensitive probe of new physics beyond vanilla inflation.
Optical light curves of light-weight supermassive black holes produced by the Zwicky Transient Facility Forced Photometry Service
Creators: name: Demianenko, Mariia
name: Chilingarian, Igor
name: Grishin, Kirill
name: Goradzhanov, Vladimir
name: Toptun, Victoria
name: Katkov, Ivan
name: Kuzmin, Ivan
Publisher: name: arXiv
Year: 2021
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: In this paper, we present an algorithm to correct optical light curves obtained using The Zwicky Transient Facility Forced Photometry Service and its application to the analysis of optical variability of 136 actvie galactic nuclei (AGN) powered by "light-weight" supermassive black holes (SMBH; $M_{BH}$<2*10^6 $\odot$) including 24 intermediate-mass black holes (IMBH; $M_{BH}$<2*10^5 $\odot$). We detected variability in nearly all sources and also analyzed its dependence on the X-ray luminosity for 101 objects. We also identified a previously unknown candidate tidal disruption event (TDE) in SDSS~J112637.74+513423.0.
description: 4 pages, 5 figures. Astronomy at the epoch of multimessenger studies. Proceedings of the VAK-2021 conference, Aug 23-28, 2021 - Moscow, 2021
Biotin tagging coupled with amino acid-coded mass tagging for efficient and precise screening of interaction proteome in mammalian cells
Creators: name: Bao, Hui-Min
name: He, Yu-Fei
name: Tang, Si-Wei
name: Du, Ru-Yun
name: Chen, Xian
name: Xiao, Xiao-Feng
name: Zuo, Shuai
name: Yang, Peng-Yuan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: In mammalian cells, when tandem affinity purification (TAP) approach is employed, the existence of untagged endogenous target protein and repetitive washing steps together result in overall low yield of purified/stable complexes and the loss of weakly and transiently interacting partners of biological significance. To avoid the trade-offs involving in methodological sensitivity, precision, and throughput here we introduce an integrated method, biotin tagging coupled with amino acid-coded mass tagging (BioCAT) for highly sensitive and accurate screening of mammalian protein-protein interactions (PPIs). Without the need of establishing a stable cell line, using a short peptide tag which could be specifically biotinylated in vivo, the biotin-tagged target/bait protein was then isolated along with its associates efficiently by streptavidin magnetic microbeads in a single step. In a pulled-down complex amino acid-coded mass tagging (AACT) serves as ‘in-spectra’ quantitative markers to distinguish those bait-specific interactors from non-specific background proteins under stringent criteria. Applying this BioCAT approach, we first biotin-tagged in vivo a multi-functional protein family member, 14-3-3ε, which was expressed at close to endogenous level. Starting with approximately 20 millions of 293T cells which were significantly less than what needed for a TAP run, 266 specific interactors of 14-3-3ε were identified in high confidence.
Global analysis of the rat and human platelet proteome - the molecular blueprint for illustrating multi-functional platelets and cross-species function evolution
Creators: name: Yang, Pengyuan
name: Liu, Na
name: Dai, Ying
name: Yu, Yanbao
name: Chen, Xian
name: Yun, Dong
name: Leng, Taohua
name: Yao, Jun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Emerging evidences indicate that blood platelets function in multiple biological processes including immune response, bone metastasis and liver regeneration in addition to their known roles in hemostasis and thrombosis. Global elucidation of platelet proteome will provide the molecular base of these platelet functions. Here, we set up a high throughput platform for maximum exploration of the rat/human platelet proteome using integrated proteomics technologies, and then applied to identify the largest number of the proteins expressed in both rat and human platelets. After stringent statistical filtration, a total of 837 unique proteins matched with at least two unique peptides were precisely identified, making it the first comprehensive protein database so far for rat platelets. Meanwhile, quantitative analyses of the thrombin-stimulated platelets offered great insights into the biological functions of platelet proteins and therefore confirmed our global profiling data. A comparative proteomic analysis between rat and human platelets was also conducted, which revealed not only a significant similarity, but also an across-species evolutionary link that the orthologous proteins representing ‘core proteome’, and the ‘evolutionary proteome’ is actually a relatively static proteome.
Measurement of the drift field in the ARGONTUBE LAr TPC with 266~nm pulsed laser beams
Creators: name: Ereditato, A.
name: Goeldi, D.
name: Janos, S.
name: Kreslo, I.
name: Luethi, M.
name: von Rohr, C. Rudolf
name: Schenk, M.
name: Strauss, T.
name: Weber, M. S.
name: Zeller, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: ARGONTUBE is a liquid argon time projection chamber (LAr TPC) with a drift field generated in-situ by a Greinacher voltage multiplier circuit. We present results on the measurement of the drift-field distribution inside ARGONTUBE using straight ionization tracks generated by an intense UV laser beam. Our analysis is based on a simplified model of the charging of a multi-stage Greinacher circuit to describe the voltages on the field cage rings.
MR-AHC: A fast, efficient and robust method for two-sample summary data Mendelian Randomization based on Agglomerative Hierarchical Clustering
Creators: name: Liang, Xiaoran
Publisher: name: Zenodo
Year: 2023
Subjects: MLTC, Multimorbidity, Causal Inference, GWAS, Mendelian Randomization

description: Slides presented by Dr Xiaoran Liang at the Early Career Researcher Lunchtime session on 2 March 2023. This series of sessions is organised by the Research Support Facility of the AI for Multiple Long-term Conditions programme.
How chameleons core dwarfs with cusps
Creators: name: Lombriser, Lucas
name: Peñarrubia, Jorge
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The presence of a scalar field that couples nonminimally and universally to matter can enhance gravitational forces on cosmological scales while restoring general relativity in the Solar neighborhood. In the intermediate regime, kinematically inferred masses experience an additional radial dependence with respect to the underlying distribution of matter, which is caused by the increment of gravitational forces with increasing distance from the Milky Way center. The same effect can influence the internal kinematics of subhalos and cause cuspy matter distributions to appear core-like. Specializing to the chameleon model as a worked example, we demonstrate this effect by tracing the scalar field from the outskirts of the Milky Way halo to its interior, simultaneously fitting observed velocity dispersions of chemo-dynamically discriminated red giant populations in the Fornax and Sculptor dwarf spheroidals. Whereas in standard gravity these observations suggest that the matter distribution of the dwarfs is cored, we find that in the presence of a chameleon field the assumption of a cuspy Navarro-Frenk-White profile becomes perfectly compatible with the data. Importantly, chameleon models also predict the existence of slopes between two stellar subcomponents that in Newtonian gravity would be interpreted as a depletion of matter in the dwarf center. Hence, an observation of such an apparently pathological scenario may serve as a smoking gun for the presence of a chameleon field or a similar modification of gravity, independent of baryonic feedback effects. In general, measuring the dynamic mass profiles of the Milky Way dwarfs provides stronger constraints than those inferred from the screening scale of the Solar System since these are located at greater distances from the halo center.
description: 5 pages, 1 figure
Discovery of biomarker candidates for coronary artery disease from an APOE-knock out mouse model using iTRAQ-based multiplex quantitative proteomics
Creators: name: Yu, Yanbao
name: Jing, Linhong
name: Hines, Maria Warren
name: Chen, Xian
name: Dicheva, Nedyalka
name: Parker, Carol E.
name: Seo, David
name: Ginsburg, Geoffrey S.
name: Schwinn, Debra
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Due to the lack of precise markers indicative of its occurrence and progression, coronary artery disease (CAD), the most common type of heart diseases, is currently associated with high mortality in the United States. To systemically identify novel protein biomarkers associated with CAD progression for early diagnosis and possible therapeutic intervention, we employed an iTRAQ-based quantitative proteomic approach to analyze the proteome changes in the plasma collected from a pair of wild type versus apolipoprotein E knockout (APOE −/−) mice which were fed with a high fat diet. In a multiplex manner ITRAQ serves as the quantitative ‘in-spectra’ marker for ‘cross-sample’ comparisons to determine the differentially expressed/secreted proteins caused by APOE knock-out. To obtain the most comprehensive proteomic datasets from this CAD-associated mouse model we applied both MALDI and ESI-based mass spectrometric (MS) platforms coupled with two different schemes of multidimensional liquid chromatography (2D-LC) separation. We then comparatively analyzed a series of the plasma samples collected at six and twelve weeks after the mice were fed with fat diets, where the 6-week or 12-week time point represents the early or intermediate phase of the fat-induced CAD, respectively. We then categorized those proteins showing abundance changes in accordance with APOE depletion. Several proteins such as the gamma and beta chains of fibrinogen, apolipoprotein B, apolipoprotein C-I, and thrombospondin-4 were among the previously known CAD markers identified by other methods. Our results suggested that these unbiased proteomic methods are both feasible and a practical means of discovering potential biomarkers associated with CAD progression.
Genetics and Epigenetics of Eating Disorders
Creators: name: Zerwas, Stephanie
name: Bulik, Cynthia M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Two key features characterize a modern view of eating disorder etiology. First, almost all risk and protective factors, both genetic and environmental, are probabilistic, rather than deterministic. Second, the old debate pitting nature against nurture is overly simplistic. Nature and nurture represent opposite sides of the same etiological coin rather than opposing influences. Eating disorder psychopathology is a function of nature and nurture rather nature or nurture. Therefore, the foremost goal of current genetic research on eating disorders is to identify all loci and pathways that confer risk or protection. The key advantage of genetic studies is that causation can be inferred because exposure to the genetic risk factor begins at conception and before disease onset. The second goal is to discover the pathophysiology underlying eating disorder development. The third is to use identified loci to inform prevention and treatment approaches.
Posterior probability of linkage analysis of autism dataset identifies linkage to chromosome 16
Creators: name: Childress, Deborah
name: Piven, Joseph
name: Bartlett, Christopher W.
name: Vieland, Veronica J.
name: Wassink, Thomas H.
name: Sheffield, Val C.
name: Goedken, Rhinda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: To apply phenotypic and statistical methods designed to account for heterogeneity to linkage analyses of the autism Collaborative Linkage Study of Autism (CLSA) affected sibling pair families.
Motivational Strategies in Second Language Learning: The Role of Self – Determination and Flow Theories in Gamification
Creators: name: P., Arundhathi
name: Dr. A., Anitha
Publisher: name: Zenodo
Year: 2024

description: This paper explores how incorporating motivational strategies from Self-Determination Theory (SDT) and Flow Theory into gamified learning environments can enhance second language learning. SDT emphasizes the importance of autonomy, competence, and relatedness in fostering intrinsic motivation, which is crucial for sustained learning. Flow Theory describes the optimal mental state where learners are fully engaged and highly efficient. By applying these theories to gamification—using game-like elements to boost motivation—this study aims to identify effective methods for improving language acquisition. Through research and examples, the paper highlights how integrating SDT and Flow Theory in gamified language learning can increase motivation, engagement, and proficiency in learners
Genome-wide scan for self-rating of the effects of alcohol (SRE) in American Indians
Creators: name: Ehlers, Cindy L.
name: Wilhelmsen, Kirk C.
name: Schuckit, Marc A.
name: Gizer, Ian R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: This study’s aims were to map loci linked to self-rating of the effects of alcohol and to determine if there was overlap with loci previously mapped for other substance dependence phenotypes in an American Indian community at high risk for substance dependence.
Genome-wide linkage scan of antisocial behavior, depression, and impulsive substance use in the UCSF family alcoholism study
Creators: name: Wilhelmsen, Kirk C.
name: Gilder, David A.
name: Feiler, Heidi S.
name: Vieten, Cassandra
name: Gizer, Ian R.
name: Ehlers, Cindy L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Epidemiological and clinical studies suggest that rates of antisocial behavior, depression, and impulsive substance use are increased among individuals diagnosed with alcohol dependence relative to those who are not. Thus, the present study conducted genome-wide linkage scans of antisocial behavior, depression, and impulsive substance use in the University of California at San Francisco Family Alcoholism Study.
Crystallography and Physical Properties of BaCo2As2, Ba{0.94}K{0.06}Co2As2 and Ba{0.78}K{0.22}Co2As2
Creators: name: Anand, V. K.
name: Quirinale, D. G.
name: Lee, Y.
name: Harmon, B. N.
name: Furukawa, Y.
name: Ogloblichev, V. V.
name: Huq, A.
name: Abernathy, D. L.
name: Stephens, P. W.
name: McQueeney, R. J.
name: Kreyssig, A.
name: Goldman, A. I.
name: Johnston, D. C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The crystallographic and physical properties of polycrystalline and single crystal samples of BaCo2As2 and K-doped Ba{1-x}K{x}Co2As2 (x = 0.06, 0.22) are investigated by x-ray and neutron powder diffraction, magnetic susceptibility chi, magnetization, heat capacity Cp, {75}As NMR and electrical resistivity rho measurements versus temperature T. The crystals were grown using both Sn flux and CoAs self-flux, where the Sn-grown crystals contain 1.6-2.0 mol% Sn. All samples crystallize in the tetragonal ThCr2Si2-type structure (space group I4/mmm). For BaCo2As2, powder neutron diffraction data show that the c-axis lattice parameter exhibits anomalous negative thermal expansion from 10 to 300 K, whereas the a-axis lattice parameter and the unit cell volume show normal positive thermal expansion over this T range. No transitions in BaCo2As2 were found in this T range from any of the measurements. Below 40-50 K, we find rho ~ T^2 indicating a Fermi liquid ground state. A large density of states at the Fermi energy D(EF) ~ 18 states/(eV f.u.) for both spin directions is found from low-T Cp(T) measurements, whereas the band structure calculations give D(EF) = 8.23 states/(eV f.u.). The {75}As NMR shift data versus T have the same T dependence as the chi(T) data, demonstrating that the derived chi(T) data are intrinsic. The observed {75}As nuclear spin dynamics are consistent with the presence of ferromagnetic and/or stripe-type antiferromagnetic spin fluctuations. The crystals of Ba{0.78}K{0.22}Co2As2 were grown in Sn flux and show properties very similar to those of undoped BaCo2As2. On the other hand, the crystals from two batches of Ba{0.94}K{0.06}Co2As2 grown in CoAs self-flux show evidence of weak ferromagnetism at T < 10 K with small ordered moments at 1.8 K of 0.007 and 0.03 muB per formula unit, respectively.
description: 23 pages, 27 figures, 3 tables, 72 references
title: d3.js and its potential in data visualization
Creators: name: Rothenhäusler, Luis
Publisher: name: Technische Hochschule Brandenburg
Year: 2022
Subjects: subject: 004 Datenverarbeitung; Informatik

description: Diese Arbeit gibt einen Einblick sowie eine Einschätzung eines Code-basierten Werkzeuges zur Datenvisualierung, der d3js bibliothek für JavaScript. Es werden nicht nur das Potential, sondern auch die Vor- und Nachteile evaluiert. Weiterhin wird eine Einschätzung gegeben, wann der Einsatz dieses Werkzeuges sinnvoll ist. Um diese Einschätzungen treffen zu können, werden einige Di- agramme, bezüglich der aktuellen Flüchtlichgssituation, die aufgrund des bewaffneten Ukrainekonfilktes besteht, erstellt. Dafür werden zunächst die nötigen Grundlagen erklärt. Dies umfasst sowohl Daten und Datentypen, als auch Diagramme und deren Aufbau. Abschließend werden die erstellten Diagramme, sowie d3js im Diskussionsteil ausgewertet. Da d3js in reinem JavaScript implementiert ist, lässt es sich problem- los mit anderen Frameworks kombinieren. Der Fokus von d3js liegt auf der schnellen und einfachen Manipulation von Elementen im Document Object Model. d3js ist jedoch kein Werkzeug, mit dem in wenigen Zeilen Quell- code ganze Diagramme erstellt werden können. Vielmehr müssen sowohl die einzelnen Elemente eines Diagrammes, wie auch deren Position und Ausse- hen händisch definiert werden. Das ermöglicht ein Höchstmaß an Kontrolle über das Aussehen und Verhalten der Diagramme. Es ist jedoch auch zeitin- tensiv und führt eventuell zur Implementation unübersichtlicher Diagramme. Gepaart mit der hohen initialen Lernkurve kann die Nutzung von d3js nur in speziellen Fällen, welche die volle Kontrolle über Aussehen und Verhalten von Diagrammen benötigen, empfohlen werden.
A simple relation of guessing probability in quantum key distribution
Creators: name: Su, Hong-Yi
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Given a communication system using quantum key distribution, the receiver can be seen as one who tries to guess the sender's information just as potential eavesdroppers do. The receiver-eavesdropper similarity thus implies a simple relation in terms of guessing probability and correctness of sifted keys, related with the distance-based, information-theoretic security. The tolerable regions of error rates determined by such a guessing-probability-based relation are shown to be close to those determined by security criteria. Thus, an alternative perspective on applying guessing probability in analyzing quantum key distribution issues is here provided. Examples of two specific protocols are illustrated. Our results contribute to evaluating an important element in communication study, and may provide useful reference for the security analysis of quantum key distribution protocols.
description: 10 pages, 1 figure, 1 table; accepted in New Journal of Physics
CC Sculptoris: Eclipsing SU UMa-Type Intermediate Polar
Creators: name: Kato, Taichi
name: Hambsch, Franz-Josef
name: Oksanen, Arto
name: Starr, Peter
name: Henden, Arne
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We observed the 2014 superoutburst of the SU UMa-type intermediate polar CC Scl. We detected superhumps with a mean period of 0.05998(2) d during the superoutburst plateau and during three nights after the fading. During the post-superoutburst stage after three nights, a stable superhump period of 0.059523(6) d was detected. We found that this object is an eclipsing system with an orbital period of 0.058567233(8) d. By assuming that the disk radius in the post-superoutburst phase is similar to those in other SU UMa-type dwarf novae, we obtained a mass ratio of q=0.072(3) from the dynamical precession rate of the accretion disk. The eclipse profile during outbursts can be modeled by an inclination of 80.6+/-0.5 deg. The 2014 superoutburst was preceded by a precursor outburst and the overall appearance of the outburst was similar to superoutbursts in ordinary SU UMa-type dwarf novae. We showed that the standard thermal-tidal instability model can explain the outburst behavior in this system and suggest that inner truncation of the disk by magnetism of the white dwarf does not strongly affect the behavior in the outer part of the disk.
description: 11 pages, 8 figures, accepted for publication in PASJ
MooringSense Project 2nd WorkShop - Overall Progress
Creators: name: Fundación Centro Tecnológico CTC
Publisher: name: Zenodo
Year: 2023

description: MooringSense Project 2nd WorkShop - Overall Progress 
Holded during WindEurope 2022, BEC (Bilbao, Spain) | Bilbao Room – Level 2       
https://windeurope.org/annual2022/networking/mooringsense
TUESDAY 5 APRIL 2022
DURATION: 15:00 – 18:00 CET
Single fermion manipulation via superconducting phase differences in multiterminal Josephson junctions
Creators: name: van Heck, B.
name: Mi, S.
name: Akhmerov, A. R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We show how the superconducting phase difference in a Josephson junction may be used to split the Kramers degeneracy of its energy levels and to remove all the properties associated with time reversal symmetry. The superconducting phase difference is known to be ineffective in two-terminal short Josephson junctions, where irrespective of the junction structure the induced Kramers degeneracy splitting is suppressed and the ground state fermion parity must stay even, so that a protected zero-energy Andreev level crossing may never appear. Our main result is that these limitations can be completely avoided by using multi-terminal Josephson junctions. There the Kramers degeneracy breaking becomes comparable to the superconducting gap, and applying phase differences may cause the change of the ground state fermion parity from even to odd. We prove that the necessary condition for the appearance of a fermion parity switch is the presence of a "discrete vortex" in the junction: the situation when the phases of the superconducting leads wind by $2π$. Our approach offers new strategies for creation of Majorana bound states as well as spin manipulation. Our proposal can be implemented using any low density, high spin-orbit material such as InAs quantum wells, and can be detected using standard tools.
description: Source code available as ancillary files. 10 pages, 7 figures. v2: minor changes, published version
title: Vergleich moderner Frontend-Technologien zur Erstellung von Single-Page-Webanwendungen
Creators: name: Diel, Alexander
Publisher: name: Technische Hochschule Brandenburg
Year: 2022
Subjects: subject: 006 Spezielle Computerverfahren

description: In der heutigen Zeit finden Single-Page-Webanwendung immer mehr Verwendung. Entsprechend dieser Entwicklung wurden Technologien, zur Erstellung von Single-Page-Webanwendungen, angefertigt. Um ihre Unterschiede und individuellen Anwendungsmöglichkeiten zu ermitteln, wurde mit den drei populärsten Technologien eine Webanwendung gebaut und eine Evaluation anhand einer Reihe von Kriterien durchgeführt.
Exploiting locality in quantum computation for quantum chemistry
Creators: name: McClean, Jarrod R.
name: Babbush, Ryan
name: Love, Peter J.
name: Aspuru-Guzik, Alán
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Accurate prediction of chemical and material properties from first principles quantum chemistry is a challenging task on traditional computers. Recent developments in quantum computation offer a route towards highly accurate solutions with polynomial cost, however this solution still carries a large overhead. In this perspective, we aim to bring together known results about the locality of physical interactions from quantum chemistry with ideas from quantum computation. We show that the utilization of spatial locality combined with the Bravyi-Kitaev transformation offers an improvement in the scaling of known quantum algorithms for quantum chemistry and provide numerical examples to help illustrate this point. We combine these developments to improve the outlook for the future of quantum chemistry on quantum computers.
How a Stressed Local Public System Copes With People in Psychiatric Crisis
Creators: name: Morrissey, Joseph
name: Wells, Rebecca
name: Hall, Marissa
name: La, Elizabeth Holdsworth
name: Lich, Kristen Hassmiller
name: Blouin, Rachel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: In order to bolster the public mental health safety net, we must first understand how these systems function on a day-to-day basis. This study explored how individual attributes and organizational interdependencies within one predominantly urban US county affected responses to individuals’ needs during psychiatric crises. We interviewed clinicians and managers within the crisis response network about people at immediate risk of psychiatric hospitalization, what had happened to them during their crises, and factors affecting services provided (N = 94 individuals and 9 agencies). Social network diagrams depicted patterns of referrals between agencies. Iterative coding of interview transcripts was used to contextualize the social network findings. Often, agencies saw crises through to resolution. However, providers also limited the types of people they served, leaving many people in crisis in limbo. This study illustrates how attributes of individuals with mental illness, service providers and their interactions, and state and federal policies intersect to shape the trajectories of individuals during psychiatric crises. Understanding both the structures of current local systems and their contexts may support continued evolution toward a more humane and robust safety net for some of our society’s most vulnerable members.
Biinvariant functions on the group of transformations leaving a measure quasiinvariant
Creators: name: Neretin, Yuri A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Functional Analysis (math.FA)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 22E66, 28D99, 22F10, 28E99

description: Let $Gms$ be the group of transformations of a Lebesgue space leaving the measure quasiinvariant, let $Ams$ be its subgroup consisting of transformations preserving the measure. We describe canonical forms of double cosets of $Gms$ by the subgroup $Ams$ and show that all continuous $Ams$-biinvariant functions on $Gms$ are functionals on of the distribution of a Radon--Nikodym derivative.
description: 16p., to appear in Sbornik Math
How Many Assertive Community Treatment Teams Do We Need?
Creators: name: Morrissey, Joseph P.
name: Cuddeback, Gary S.
name: Meyer, Piper S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Assertive community treatment (ACT) reduces hospitalizations for persons with severe mental illness. However, not everyone who needs ACT receives it. Without empirical guidelines for ACT planning, communities are likely to underestimate or overestimate the number of teams they need; thus the capacity of the programs will not meet current needs. In this study, administrative data were used to develop empirical estimates for the number of required ACT teams. These estimates were then used to examine current conceptual guidelines for developing the number of ACT teams that communities need. Administrative data from a large, urban county were used to enumerate all persons with a severe mental illness who had three or more hospitalizations within one year (ACT eligible). Fifty-one percent of persons with a severe mental illness were found to be eligible for ACT (743 of 1,453 persons). This figure represents 2.2 percent of the county's mental health users and .06 percent of its adult population. Communities should develop enough ACT teams to serve approximately 50 percent of their populations of persons with severe mental illness or roughly .06 percent of their adult populations.
Flow-based Influence Graph Visual Summarization
Creators: name: Shi, Lei
name: Tong, Hanghang
name: Tang, Jie
name: Lin, Chuang
Publisher: name: arXiv
Year: 2014
Subjects: subject: Social and Information Networks (cs.SI)
subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Visually mining a large influence graph is appealing yet challenging. People are amazed by pictures of newscasting graph on Twitter, engaged by hidden citation networks in academics, nevertheless often troubled by the unpleasant readability of the underlying visualization. Existing summarization methods enhance the graph visualization with blocked views, but have adverse effect on the latent influence structure. How can we visually summarize a large graph to maximize influence flows? In particular, how can we illustrate the impact of an individual node through the summarization? Can we maintain the appealing graph metaphor while preserving both the overall influence pattern and fine readability? To answer these questions, we first formally define the influence graph summarization problem. Second, we propose an end-to-end framework to solve the new problem. Our method can not only highlight the flow-based influence patterns in the visual summarization, but also inherently support rich graph attributes. Last, we present a theoretic analysis and report our experiment results. Both evidences demonstrate that our framework can effectively approximate the proposed influence graph summarization objective while outperforming previous methods in a typical scenario of visually mining academic citation networks.
description: to appear in IEEE International Conference on Data Mining (ICDM), Shen Zhen, China, December 2014
Die Schlüsselrolle von Schulleitungen bei einer ganzheitlichen Bildung für nachhaltige Entwicklung
Creators: name: Scholz, Leander
name: Wagner, Ingo
name: Wohlfart, Olivia
Publisher: name: Karlsruher Institut für Technologie (KIT)
Year: 2024
Subjects: Schulleitung
BNE
Whole institutional Approach
Schulentwicklung

description: Schulen als tragende Säulen einer Bildung für nachhaltige Entwicklung (BNE) für Kinder und Jugendliche sollen zukunftsfähiges Denken und Handeln theoretisch und praktisch vermitteln (Holst et al., 2024; Vereinte Nationen, 2015). Dabei nehmen Schulleitungen eine Schlüsselrolle bei der Implementierung von BNE als Schulentwicklungsmaßnahme ein (Stricker et al., 2023). Vor dem theoretischen Hintergrund des „Whole Institutional Approach“ (Holst, 2023) untersucht die vorliegende Studie exemplarisch die Rolle von Schulleitungen in der Ein- und Durchführung des FreiDay als BNE-Maßnahme. 
Mittels leitfadengestützter Interviews werden im Mai und Juni 2024 insgesamt 10 Schulleiter:innen in Baden-Württemberg befragt, wie sie ihre Rolle in der (geplanten) Einführung des FreiDay wahrnehmen. Die transkribierten Interviews werden mittels thematischer Inhaltsanalyse nach Braun und Clarke (2006) analysiert, um die jeweils wahrgenommene Rolle vor dem ganzheitlichen Ansatz des Whole Institutional Approach sowie Chancen und Herausforderungen des Schulentwicklungsprozesses aus Perspektive der Schulleitungen zu diskutieren.
How Many Forensic Assertive Community Treatment Teams Do We Need?
Creators: name: Cuddeback, Gary S.
name: Morrissey, Joseph P.
name: Cusack, Karen J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Despite the growing interest in forensic assertive community treatment (FACT), there is no standardized definition of FACT eligibility and no guidelines for how many FACT teams communities may need. In this brief report a definition for FACT eligibility is proposed—severe and persistent mental illness and three jail detentions in a one-year period— and modeled by using 5.5 years of administrative data (July 1, 1993, through December 31, 1998) from a large, urban county in the western United States. Findings suggest that large, urban communities should develop enough FACT teams to serve approximately 44% of their populations of persons with severe mental illness, or roughly .05% of their adult populations. Developing standardized eligibility criteria for FACT is an important first step toward developing its evidence base.