cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
‘Excellent for mind, body and spirit’: Participant, facilitator, and community stakeholder experiences of music and movement for health
Creators: name: O'Malley, Nicola
name: O'Reilly, Siobhán
name: Cheung, Pui Sze
name: Fitzell, Caroline
name: Ni Bhriain, Orfhlaith
name: Moss, Hilary
name: Gowran, Rosemary
name: Louw, Quinette
name: Woods, Catherine
name: O’Neill, Desmond
name: Glynn, Liam
name: Cavanagh, Mary
name: Maher, Catherine
name: Salsberg, Jon
name: Thabane, Lehana
name: Clifford, Amanda M.
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 4201
subject: Allied health and rehabilitation science
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 3603
subject: Music
classificationCode: 4205
subject: Nursing
classificationCode: 4207
subject: Sports science and exercise

description: Background and purpose: Arts-based interventions are an emerging area of interest in health research for older adults. Music and Movement for Health (MMH) is one such systematically developed interdisciplinary arts-based intervention designed to enhance health and wellbeing of older adults. The objective of this qualitative study was to explore the opinions and experiences of participants, facilitators, and community stakeholders of the MMH intervention.Materials and methods: This embedded qualitative study was completed as part of a wider evaluation of the MMH intervention. A purposive sample of older adults who had completed MMH (n = 71), facilitators (n = 8) and community stakeholders (n = 4) participated in this study. Data were collected through a combination of focus groups and telephone/virtual interviews. Data were analysed using inductive thematic analysis.Results: Data analysis led to the generation of the overarching theme ‘Positive ageing in place’, which encom passed two themes: (1) ‘Intersection of exercise and arts’ and (2) ‘Fostering a sense of belonging’, and five subthemes. MMH was viewed as a unique arts-based intervention that combined participants’ interest in music and dance and had many perceived physical and psychological benefits. Additionally, MMH provided routine and social opportunities to older adults, which were particularly valued in the aftermath of the COVID-19 pandemic. Conclusion: The provision of exercise through the arts was enjoyable and, resultantly, desirable to many older adults, with perceived positive physical and psychosocial outcomes. Consequently, the use of arts-based in terventions for health promotion and social opportunities among older adults warrants further investigation. Trial registration: ISRCTN35313497.
Tooth survival and clinical outcomes up to 26 years after guided tissue regeneration therapy in deep intra‐bony defects: Follow‐up investigation of three randomized clinical trials
Creators: name: Cieplik, Fabian
name: Ihlenfeld, Insa
name: Hiller, Karl-Anton
name: Pummer, Andreas
name: Schmalz, Gottfried
name: Buchalla, Wolfgang
name: Christgau, Michael
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: LONG-TERM; PERIODONTAL REGENERATION; BIOABSORBABLE BARRIERS; CONSENSUS REPORT; GLOBAL BURDEN; DISEASES; MEMBRANES; SURGERY; CARIES; guided tissue regeneration; intra-bony defects; long-term results; periodontal surgery
subject: 610 Medizin

description: Aim To investigate tooth survival and clinical long-term outcomes up to 26 years following guided tissue regeneration (GTR) therapy in deep intra-bony defects. Methods Patients from three prospective clinical split-mouth studies, which investigated the outcomes of GTR therapy, were re-evaluated 21-26 years after surgery independent of the membrane type used, and tooth survival was assessed according to several site-specific and patient-related factors. Results About 50 patients contributing 102 defects were available for this long-term follow-up. After up to 26 years (median 23.3 years), 52.9% of the teeth were still in situ. The median survival of the extracted teeth was 13.8 years. Patients with diabetes mellitus and/or smoking history lost significantly more teeth in the long term. Compared to the 1-year situation, there was no new median CAL loss after up to 26 years in the teeth which were still in situ. Conclusions Within the limitations of this study, our data show that more than 50% of the initially seriously diseased teeth were still in situ up to 26 years following GTR therapy despite an overall limited adherence to SPT. In the majority of these teeth, the CAL gain 1 year after GTR could be maintained over this long period.
Galeatus major PUTON 1886
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Galeatus
Galeatus major

description: Galeatus major PUTON, 1886
I T A I t a l i e n: Calabria, Camigliatello Silano, 2 Ex., 15. VI. 1962, leg. Budberg.
M A R M a r o k k o: Fez-Meknès,AinLeuh, 2Ex., 4.VIII.1959,leg.Eckerlein H.
T U N T u n e s i e n: Jendouba, Ain-Draham, 3 Ex., 18. V. 1978, leg. Péricart J.; Ain Draham, 1 Ex., 18. V. 1978, leg. Péricart J.
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 109, DOI: 10.5281/zenodo.7507194
From Professional Vision to Fostering Critical L2 Classroom Discourse Competence
Creators: name: Schildhauer, Peter
Publisher: name: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht. (DiMawe)
Year: 2024

description: This article argues that a crucial aspect of teaching in inclusive (in fact: in all!) English language classrooms is not only using learner-oriented teaching methods, but also interacting in a learner-oriented, empowering way. It therefore proposes that pre-service English language teachers develop Critical L2 Classroom Discourse Competence as part of their university education and suggests that this competence can be fostered by enhancing the pre-service teacher’s professional vision. As a means to do so, the article presents material that has been implemented in an advanced class for future English teachers at Bielefeld University. The material invites the students to engage in the micro-analysis of a video-sequence that was recorded in an inclusive English classroom (year 5). Insights into student products generated in the seminar as well as course evaluations suggest that the students’ professional vision as well as a sensitivity to classroom discourse in inclusive contexts may be promoted by the suggested material.
description: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht. (DiMawe), Bd. 6 Nr. 2 (2024): Inklusive Fremdsprachendidaktik: Evidenzbasierte Zugänge und Perspektiven aus den Fächern Englisch und Latein
The Proof of the Pudding Is in the Making: Reflections on Social Justice Teacher Education in English Language Teaching
Creators: name: Louloudi, Eleni
name: Schildhauer, Peter
Publisher: name: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht. (DiMawe)
Year: 2024

description: This contribution proposes five fundamental elements of social justice teaching as applied in language teacher education. It does so by taking into consideration already existing university formats – a seminar and a student-conference – which were built on the foundation of critical literacy pedagogies. By defining these elements, our goal is not only to prompt a discussion about social justice in language teacher education, but to center our students’ authentic voices and opinions about their own learning experiences.
description: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht. (DiMawe), Bd. 6 Nr. 2 (2024): Inklusive Fremdsprachendidaktik: Evidenzbasierte Zugänge und Perspektiven aus den Fächern Englisch und Latein
Inklusive Fremdsprachendidaktiken: Rückblick auf eine Forschungskooperation der Latein- und Englischdidaktik
Creators: name: Schildhauer, Peter
name: Sauer, Jochen
name: Louloudi, Eleni
Publisher: name: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht. (DiMawe)
Year: 2024

description: Dieser Artikel blickt auf eine Forschungskooperation zurück, die im Rahmen der Teilmaßnahme „Inklusive Fremdsprachendidaktiken“ des Bielefelder QLB-Projekts BiProfessional zwischen Vertreter*innen der Latein- und der Englischdidaktik stattgefunden hat. Zunächst werden Anknüpfungspunkte der beiden Fremdsprachendisziplinen untereinander explizit gemacht. Danach lotet der Beitrag aus, auf welche Weise das Konzept Inklusion in den Fachdidaktiken der beiden Sprachen in den letzten Jahrzehnten etabliert bzw. weiterentwickelt wurde. Auf dieser Grundlage wird eine Heuristik abgeleitet, die zwischen einem Blick auf Inklusion als unterrichtsmethodischer Herausforderung und Inklusion als Bildungsgegenstand unterscheidet. Darauf aufbauend wird jeweils ein empirisches Forschungsprojekt für die Englisch- und für die Lateindidaktik skizziert, das – entsprechend der unterschiedlichen Schwerpunktsetzungen der beiden Fächer – den Fokus auf die Unterrichtsmethodik (Lateindidaktik) und auf den Bildungsgegenstand (Englischdidaktik) legt. Abschließend werden gemeinsame „Lessons Learned“ insbesondere mit Blick auf Herausforderungen der Lehrer*innenbildung reflektiert, die teilweise bereits Teil der jeweiligen Forschungsstränge waren.
description: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht. (DiMawe), Bd. 6 Nr. 2 (2024): Inklusive Fremdsprachendidaktik: Evidenzbasierte Zugänge und Perspektiven aus den Fächern Englisch und Latein
Parents’ perspectives on speech-language assessment for their preschool-aged children: A scoping review
Creators: name: Wenzel, Shanda Duggleby
name: Pritchard-Wiart, Lesley
name: Charest, Monique
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: Assessment allows speech-language pathologists to identify clients’ strengths and needs while laying the foundation for the therapeutic relationship. However, the extent to which parents’ experiences with assessment has been explored in the literature is unclear. The purposes of this review were to: a) Identify and summarise the available literature on parents’ experiences with speech-language assessment for their preschool-aged children, and b) identify gaps in the literature. Using an established framework for scoping reviews, the authors conducted a search of seven databases including literature up to April 2024. Two researchers independently reviewed articles for inclusion and discussed discrepancies, and a third researcher provided input when consensus could not be reached. Data extracted included study aims, participant information, and the aspects of the assessment process including the lead-up to the assessment, the assessment itself, receiving a diagnosis, and interim supports following the assessment. Ten studies met inclusion criteria, however, only three studies were focussed on parents’ experiences with speech-language assessment. In the included studies, aspects of assessment have been addressed but with limited depth and breadth. To date, the perspectives studied have primarily been those of monolingual, English-speaking mothers. Proposed reporting considerations are discussed, and clinical and research implications are explored.
Galeatus scrophicus SAUNDERS 1876
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Galeatus
Galeatus scrophicus

description: Galeatus scrophicus SAUNDERS, 1876
C Y P Z y p e r n: Limassol, Yermasoyia River, 2 Ex., 10. IX. 1964, leg. Mavromoustakis.
E S P S p a n i e n: Kanarische Inseln, Los Christianos, 1 Ex., 9. IV. 1954, leg. Remane R.
I R N I r a n: Khorasan, Golestan/ Dasht, 1 Ex., 20. V. 2001, leg. HE.
I R Q I r a k: Bagdad, Bagdad, 1 Ex., 29. IX. 1958, leg. Remane R.; Dhi Qar, Nasiriya/ Gurmat Said, 1 Ex., 15. IV. 1958, leg. Remane R.
J O R J o r d a n i e n: Schambak, 1 Ex., 24. V. 1968, leg. Klapperich J.
LBY Lybien: Wadi al-Haya, Fezzan/ Wadi Mathendous, 1 Ex., 11. XI. 2003, leg. HE.
T U N T u n e s i e n: Medenine, Djerba / Houmet Souk Umgebung, 16 Ex., 20. VI. 1983, leg. HE; Medenine, Medenine N/ Boughrara, 19 Ex., 20. III. 1983, leg. HE.
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on pages 109-110, DOI: 10.5281/zenodo.7507194
Lymph node ratio as a predictor for outcome in oral squamous cell carcinoma: a multicenter population-based cohort study
Creators: name: Spoerl, Steffen
name: Gerken, Michael
name: Mamilos, Andreas
name: Fischer, René
name: Nieberle, Felix
name: Klingelhöffer, Christoph
name: Meier, Johannes K.
name: Spoerl, Silvia
name: Ettl, Tobias
name: Spanier, Gerrit
name: Reichert, Torsten E.
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: PRIMARY SURGERY; SURVIVAL RATES; HEAD; CAVITY; TONGUE; CANCER; RECURRENT; SYSTEM; FRONT; CHEMOTHERAPY; Oral squamous cell carcinoma; Depth of invasion; Resection margin; Malignancy grading
subject: 610 Medizin

description: Objectives The present study evaluated the predictive value of staging and grading parameters concerning the presence of lymph-node metastases, overall survival (OS), and relapse-free survival (RFS) of patients with oral squamous cell carcinoma (OSCC). Materials and methods HE-stains of 135 surgically treated (R0) primary OSCCs were analyzed using a both microscopic and software-based approach. Depth of invasion (DOI) and resection margins (RM) were measured, and each case was graded according to the malignancy grading system as described by Anneroth et al. and Bryne et al. on two different sites of the tumor (surface and invasion front; TS and IF). Results Parameters that could be identified as significant predictors of OS and RFS were UICC cancer stage (p = 0.009 andp = 0.012); pT-stage as defined in the 7th edition (p = 0.029 and 0.015) and, after restaging using DOI, 8th edition (p = 0.023 andp = 0.005) of the TNM classification of malignant tumors; the presence of lymphonodular metastases (LM) (p = 0.004 andp = 0.011); degree of keratinization (p = 0.029 andp = 0.042); and pattern of growth (p = 0.029 andp = 0.024) at the TS after applying a binary scale for both parameters. Also, when directly comparing the most extreme subgroups (scores 1 and 4) of lymphoplasmacytic infiltration at the IF, there was a significant difference in OS (p = 0.046) and RFS (p = 0.005). Invasion of blood vessels (p = 0.013) and perineural invasion (p = 0.023) were significantly associated with a lower OS. Age lower than 60 years (univariatep = 0.029, multivariatep = 0.031), infiltration of lymphatic vessels (p = 0.003), infiltration of nerves (p = 0.010), pT-stage (8th edition) (p = 0.014), degree of keratinization at the IF (p = 0.033), and nuclear polymorphism at the IF (p = 0.043) after conversion to a binary scale were found to be significant prognostic parameters regarding the presence of LM. DOI evolved as a significant predictor for OS (p = 0.006), RFS (p = 0.003), and LM (p = 0.032) in metric and grouped analysis. Conclusions The current evaluation revealed depth of invasion as strongest histologic predictor of metastatic tumor growth, overall survival, and relapse-free survival in OSCC, confirming the current adaption of the T-classification. Other distinct histologic grading parameters investigated during this study can give valuable indications of a tumor's potential aggressiveness, but the exact site, mode, and procedure need further exploration.
Galeatus spinifrons
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Galeatus
Galeatus spinifrons

description: Galeatus spinifrons (FALLÉN, 1807)
D E U D e u t s c h l a n d: Baden-Württemberg, Pfullingen / Zellertal, 1 Ex., 28. VII. 1975, leg. Rieger Chr.; Baden-Württemberg, Gutenberg, 1 Ex., 17. VII. 1980, leg. Rieger Chr.; Baden-Württemberg, Gutenberg, 1 Ex., 18. VII. 1976, leg. Rieger Chr.; Baden-Württemberg, Gutenberg, 2 Ex., 17. VII. 1980, leg. Rieger Chr.
R U S R u s s l a n d: Yakutien, Balaganach, 2 Ex., 7. VII. 1974, leg. Vinokurov.
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 110, DOI: 10.5281/zenodo.7507194
Additional file 1: of Immunological adjuvant effect of the peptide fraction from the larvae of Musca domestica
Creators: name: Liqing Chen
name: Zhang, Juan
name: Hongxiang Sun
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Extraction, purification and characterization of MDPF. (DOC 243 kb)
ЎЗБЕКИСТОН РЕСПУБЛИКАСИ ИЧКИ ИШЛАР ВАЗИРЛИГИ ЖАМОАТ ХАВФСИЗЛИГИ ДЕПАРТАМЕНТИ ПРОБАЦИЯ БОШҚАРМАСИНИНГ ФУҚАРОЛИК ЖАМИЯТИ ИНСТИТУТЛАРИ БИЛАН ҲАМКОРЛИГИ
Creators: name: Аманов, Аброржон
Publisher: name: Zenodo
Year: 2024

description: Мақолада Ўзбекистон Республикаси Ички ишлар вазирлиги Жамоат хавфсизлиги департаменти Пробация бошқармасининг фуқаролик жамияти институтлари билан ҳамкорлиги хусусида фикр юритилиб, мазкур фаолиятни янада самарали ташкил этишга оид таклиф ҳамда тавсиялар билдирилган.
Observational properties of 155 O- and B-type massive pulsating stars
Creators: name: Shi, Xiang-dong
name: Qian, Sheng-bang
name: Zhu, Li-ying
name: Liu, Liang
name: Li, Lin-jia
name: Zang, Lei
Publisher: name: arXiv
Year: 2024
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The O- and B-type (OB-type) pulsating stars are important objects to study the structure and evolution of massive stars through asteroseismology. A large amount of data from various sky surveys provide an unprecedented opportunity to search for and study this kind of variable star. We identify 155 OB-type pulsating stars or candidates, including 38 Oe/Be stars or candidates, from the data observed by TESS, LAMOST, and GAIA, which are almost new. Among the 155 objects, 87 samples are identified as SPB stars including 37 objects with pure low-frequency and 50 objects with both low- and high-frequency pulsation, and 14 samples are identified as BCEP stars with both low- and high-frequency pulsation. The H-R diagram shows that these SPB and BCEP stars are mainly located in their instability regions and in the evolutionary stage of the main-sequence with a mass range of 2.5-20 $M_{\odot}$ and 7-20 $M_{\odot}$. Two special objects show fourier spectra similar to BCEP stars but with different positions in H-R, Period-Temperature (P-T), and Period-Luminosity (P-L) diagrams. Meanwhile, 52 other targets are identified as candidates of OB-type pulsating stars. We also derive the preliminary results of the P-L relation for SPB and BCEP stars, respectively. This work also indicates that in addition to the H-R diagram, P-T and P-L diagrams are also very useful for the classification of SPB and BCEP. Further detailed analysis of these objects can dramatically increase our understanding of theories of evolution and structure for massive OB-type pulsating stars.
Additional file 1: Figure S1. of Genome-wide analysis of autophagy-associated genes in foxtail millet (Setaria italica L.) and characterization of the function of SiATG8a in conferring tolerance to nitrogen starvation in rice
Creators: name: Weiwei Li
name: Chen, Ming
name: Erhui Wang
name: Liqin Hu
name: Hawkesford, Malcolm
name: Zhong, Li
name: Chen, Zhu
name: Zhaoshi Xu
name: Liancheng Li
name: Yongbin Zhou
name: Changhong Guo
name: Youzhi Ma
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Expression analysis of autophagy-associated gene (ATG) in various foxtail millet organs. Figure S2. The transcription levels of SiATG8a in three transgenic rice lines relative to wild type rice. Figure S3. The transcription levels of 18 endogenous ATG in the three transgenic rice lines. Figure S4. SiATG8a expression and phenotype analysis in multiple foxtail millet varieties grown under nitrogen starvation conditions. Figure S5. The total nitrogen content for whole plants under normal and starvation conditions. Table S1. The autophagy-associated gene (ATG) homologue superfamily in foxtail millet. Information includes common names and locus names of the putative SiATGs in different versions of PHYTOZOME. TableS2. The autophagy-associated gene (ATG) homologue superfamily in foxtail millet. pI: isoelectric point, M: molecular weight. Table S3. Conserved motifs identified in the foxtail millet ATG family proteins using MEME software. Table S4. The Ka/Ks ratios and estimated divergence times for orthologous ATG proteins between foxtail millet and maize. Table S5. The Ka/Ks ratios and estimated divergence times for orthologous ATG proteins between foxtail millet and rice. Table S6. The Ka/Ks ratios and estimated divergence times for orthologous ATG proteins between foxtail millet and sorghum. Table S7. Foxtail millet varieties examined in this study. Table S8. Overview of the expression of ATGs in foxtail millet in response to treatment with various stresses. “+” and “-”indicate that the relative expression level of a given ATGs was up-regulated or down-regulated, respectively, in response to a given stress. The number represents the difference in expression expressed as a fold change. 0 means the absolute value are between 0 and 1;1 means ≥ 1 fold change; 2 means ≥ 2 fold change etc. Table S9. Primers used for the qRT-PCR analysis of the 37 SiATG genes. Table S10. A list of the primer sequences used for the cloning of SiATG8a and the PCR analysis of SiATG8a in transgenic rice. Table S11. Primers used for the for qRT-PCR analysis of endogenous ATG genes of rice. (DOCX 1530 kb)
Galeatus vitreus GOLUB 1974
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Galeatus
Galeatus vitreus

description: Galeatus vitreus GOLUB, 1974
K A Z K a s a c h s t a n: Turgai Prov., 2 Ex., 16. V. 1931, leg. Luppova, (1 Paratype).
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 110, DOI: 10.5281/zenodo.7507194
Rhea americana
Creators: name: Maxwell, Erin E.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Rheiformes
Rheidae
Rhea
Rhea americana

description: RHEA AMERICANA
Stage 34 (Fig. 1I)
No ossification is present at this stage. The prenasal process is slightly swollen at its tip, and is only slightly longer than Meckel’s cartilage. The roof of the nasal tectum has grown posteriorly, dorsal to the orbits. The pars canaliculi of the auditory capsule is prominent, encompassing the entire lateral posterior margin of the skull. The contact between the two rami of Meckel’s cartilage is relatively narrow.
Stage 35
The contact between the two rami of Meckel’s cartilage becomes broader in this stage. The squamosal, palatine, vomer, pterygoid, jugal, and quadratojugal are ossifying. The lacrimal is ossifying, beginning from its orbital process. The frontal process of the premaxilla is ossifying, as is the jugal process of the maxilla. The supra-angular and angular are ossified in the lower jaw. This is followed by the ossification of the parasphenoid rostrum.
Stage 37 (Fig. 2C)
The nasal is ossifying, as are the splenial, prearticular, and dentary. The jugal process of the premaxilla is ossified, but is not fused with the frontal process. The maxilla is triradiate. There are two independent, parallel ossification centres posterior to the parasphenoid rostrum; these represent the initiation of ossification of the parasphenoid lamina. The squamosal forms a process that parallels the otic process of the quadrate.
Stage 38 (late)
The parietal and frontal are ossifying, as are the quadrate and the ceratobranchials.
Stage 40+
Day 22: The supraoccipital is ossifying from a single centre. The parasphenoid alae are ossifying, as is the basisphenoid. The lacrimal is triradiate. Although the nasal lacks a descending process, the ascending process of the maxilla in R. americana is much better developed than in D. novaehollandiae. There is a hole located in the middle of the squamosal, perhaps because of osteological restructuring caused by muscle development, as hypothesized for Meleagris gallopavo (Maxwell, 2008a).
Day 26 (Fig. 1J): The basioccipital, exoccipital, laterosphenoid, prootic, opisthotic, epiotic, and mesethmoid are ossifying. The lamina dorsalis of the mesethmoid is ossifying from paired ossification centres, rather than from a single median centre. The prearticular has developed a second ossification centre, located along the posterior edge of the articular cartilage.
Day 28: The facial region of the skull has become extremely elongate. The articular is ossifying, and the dermal bones of the skull roof are in contact.
Day 30: The opisthotic and epiotic have developed large lateral exposures (Fig. 2D).
description: Published as part of Maxwell, Erin E., 2009, Comparative ossification and development of the skull in palaeognathous birds (Aves: Palaeognathae), pp. 184-200 in Zoological Journal of the Linnean Society 156 (1) on page 191, DOI: 10.1111/j.1096-3642.2009.00533.x, http://zenodo.org/record/10114794
Additional file 1:Figure S1. of Calcium/calmodulin alleviates substrate inhibition in a strawberry UDP-glucosyltransferase involved in fruit anthocyanin biosynthesis
Creators: name: Peng, Hui
name: Tianbao Yang
name: Whitaker, Bruce
name: Lingfei Shangguan
name: Jinggui Fang
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Amino acid sequence alignment of FvUGT1 and six other plant UGTs. Color and intensity change indicates the differences in the level of conservation. Dark red and dark blue represent the highest and lowest conserved levels, respectively. α-helices and β-strands are marked by black lines. The putative secondary plant glycosyltransferase (PSPG) motif is underlined by a red line and 10 conserved sugar donor interacting residues of the PSPG motif are marked with black solid triangles. The putative calmodulin-binding region in FvUGT1 is indicated by a black open box. The GenBank accession numbers or sources of proteins are FvUGT1 (KP165417; F. vesca), VtGT1 (AAB81682; grape), FaGT1 (AAU09442; F. × ananassa), Ct3GT (BAF49297; C. ternatea), MtUGT78G1 (A6XNC6.1; M. truncatula), AtUGT72B1 (Q9M156.1; A. thialiana), MtUGT71G1 (AAW56092.1; M. truncatula), and MtUGT85H2 (2PQ6_A; M. truncatula). (PDF 787 kb)
Ergebnisse der Sicca-Forschungsförderung 2016
Creators: name: Musayeva, A.
name: Gericke, A.
name: Jäger, F.
name: Paulsen, F.
name: Braun, M.
name: Fabry, B.
name: Braun, R.
name: Pauly, D.
name: Holtmann, C.
name: Geerling, G.
name: Geerling, Gerd
name: Goldblum, David
name: Horwath-Winter, Jutta
name: Jacobi, Christina
name: Kaden, Reinhard
name: Kaercher, Thomas
name: Messmer, Elisabeth
name: Paulsen, Friedrich
name: Schwarzkopff, Johannes
name: Zierhut, Manfred
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: MUSCARINIC ACETYLCHOLINE-RECEPTORS; OCULAR SURFACE; TEAR FLUID; CHRONIC GVHD; DISEASE; BIOMARKERS; SECRETION; UREA; CYTOKINES; PROTEINS; Muscarinic receptor; Urea; Tear film stability; Graft versus host disease; Eyelid tension
subject: 610 Medizin

description: TheSicca-Forderpreis(Dry Eye Award) supports the development of scientific research on the pathogenesis, diagnostics, and treatment of dry eye and ocular surface diseases. It is awarded after a limited call for proposals in German-speaking countries, written application and selection of the award winner after evaluation by a jury of ophthalmologists working in basic and clinical science. In this article examples of the results of funded projects of theSicca-Forderpreis 2016are cursorily described, which were presented at the Ophthalmological Academy of Germany 2019 (Augenarztliche Akademie Deutschland 2019) and therefore provide an insight into current scientific developments. The role of muscarinic receptors and those of urea in the pathogenesis of dry eye as well as the (missing) correlation of tear film stability, viscosity and surface tension are highlighted. A project on the early detection of ocular involvement in graft versus host disease and the idea of treating meibomian gland dysfunction with eyelid surgery techniques are also groundbreaking. The outlined projects represent the potential for further substantial developments in the understanding, diagnostics and treatment of dry eye; however, their long-term clinical relevance still needs to be established.
MOESM2 of Egg-spot matching in common cuckoo parasitism of the oriental reed warbler: effects of host nest availability and egg rejection
Creators: name: Donglai Li
name: Yanan Ruan
name: Wang, Ying
name: Chang, Alan
name: Dongmei Wan
name: Zhengwang Zhang
Publisher: name: Figshare
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: Cancer

description: Additional file 2: Table S1. Local parasitism rate and number of parasitized nests that were successfully paired with their nearby non-parasitized nests for egg-spot assessment.
Gitava distincta RODRIGUES 1986
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Gitava
Gitava distincta

description: Gitava distincta RODRIGUES, 1986 exld
R W A R u a n d a: Westprovinz, Cyangugu/ Nyakabuye, 4 Ex., 1. V. 1984, leg. MH; Westprovinz, Cyangugu/ Nyakabuye, 1 Ex., 1. VI. 1984, leg. MH; Westprovinz, Cyangugu/ Nyakabuye, 2 Ex., 10. VIII. 1984, leg. MH.
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 110, DOI: 10.5281/zenodo.7507194
MOESM6 of Egg-spot matching in common cuckoo parasitism of the oriental reed warbler: effects of host nest availability and egg rejection
Creators: name: Donglai Li
name: Yanan Ruan
name: Wang, Ying
name: Chang, Alan
name: Dongmei Wan
name: Zhengwang Zhang
Publisher: name: Figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: Cancer
subject: 60506 Virology

description: Additional file 6: Supplementary Document 1. Comparison of egg-spot parameters between cuckoo and warbler eggs from parasitized and non-parasitized nests.
MOESM5 of Egg-spot matching in common cuckoo parasitism of the oriental reed warbler: effects of host nest availability and egg rejection
Creators: name: Donglai Li
name: Yanan Ruan
name: Wang, Ying
name: Chang, Alan
name: Dongmei Wan
name: Zhengwang Zhang
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 60506 Virology

description: Additional file 5: Table S2. Summary of the published data for the empirical testing of the egg-matching hypothesis.
title: PaNcaKe statt Sandwich. Ein neues Feedback-Modell auf Basis einer qualitativen Panel-Studie
Creators: name: Haas, Barbara
name: Juen, Victoria
Year: 2024
Subjects: subject: 370 Erziehung, Schul- und Bildungswesen

description: Konstruktives, auf Leistungsverbesserung ausgerichtetes Feedback an Studierende ist entscheidend für die Entwicklung ihrer Kompetenzen und Fähigkeiten. Die vorliegende qualitative Panelstudie unterstreicht die Bedeutung von Feedback im Kontext der Reckwitz’schen Theorie des Strukturwandels in singularisierten Gesellschaften. Das vorgeschlagene PaNcaKe-Modell (positiv-negativ-konstruktiv) soll das traditionelle Sandwich-Modell ersetzen. Wiederholtes und integriertes Feedback zeigt ein großes Wirkungspotenzial, insbesondere durch zeitnahe Beurteilung, die den Erinnerungswert erhöht und das für die spätere Karriere wichtige Zeitmanagement erleichtert.
description: Forschung und Innovation in der Hochschulbildung; 22
MOESM1 of Metabolic engineering of Escherichia coli for poly(3-hydroxybutyrate) production via
            threonine bypass
Creators: name: Zhenquan Lin
name: Zhang, Yan
name: Qianqian Yuan
name: Qiaojie Liu
name: Yifan Li
name: Zhiwen Wang
name: Hongwu Ma
name: Chen, Tao
name: Xueming Zhao
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1. Table S1: Primer sequence used for genome manipulation in this study. Figure S1: Strategies for chromosomal replacement. Figure S2: Results of relative transcriptional level. Figure S3: Versions of serB - strain overexpressing combinations of native kbl-tdh and sdaA genes were tested for their ability to grow on glucose minimal medium.
Habrochila africana DRAKE 1948
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Habrochila
Habrochila africana

description: Habrochila africana DRAKE, 1948 exld
K E N K e n i a: NairobiCounty,Nairobi Umgebung, 1 Ex., 12. IV. 1978, leg. HE.
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 110, DOI: 10.5281/zenodo.7507194
Eudromia elegans I. Geoffroy Saint-Hilaire 1832
Creators: name: Maxwell, Erin E.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Tinamiformes
Tinamidae
Eudromia
Eudromia elegans

description: EUDROMIA ELEGANS
Day 9: There is no cranial ossification. The two rami of Meckel’s cartilage have a broad contact, as in ratites.
Day 10: The prenasal process is curved ventrally, as is the area of the lower jaw where the rami of Meckel’s cartilage are in contact. Dorsal outgrowth of the trabecula communis in the area of the nasal capsule initiates the formation of the parietotectal cartilage and the preoptic root of the orbital cartilage. The jugal and frontal processes of the premaxilla are ossified, as is the quadratojugal.
Day 11 (Fig. 1D): The prenasal process is straighter than in younger embryos, and only a slight terminal hook remains. The squamosal, premaxillary process of the nasal, maxilla, palatine, vomer, and jugal are ossifying, as are the dentary, supra-angular, angular, and splenial. This is followed by the ossification of the parasphenoid rostrum and lamina, the basisphenoid, parietal, frontal, lacrimal, pterygoid, quadrate, prearticular, and ceratobranchials. The ossification of the quadrate is variable, as it does not always ossify before day 12 (YPM 112522). The premaxilla completely covers the prenasal process. The maxillary process of the nasal does not contact the nasal process of the maxilla. The beak forms a rigid ossified framework, but the calvarium is not well ossified.
Day 12: The basioccipital is ossifying.
Day 14: The exoccipital, laterosphenoid, prootic, opisthotic, epiotic, and mesethmoid are ossifying (Figs 1E, 2F). The supraoccipital is ossifying from a single centre. The mesethmoid lacks a broad dorsal exposure.
description: Published as part of Maxwell, Erin E., 2009, Comparative ossification and development of the skull in palaeognathous birds (Aves: Palaeognathae), pp. 184-200 in Zoological Journal of the Linnean Society 156 (1) on page 193, DOI: 10.1111/j.1096-3642.2009.00533.x, http://zenodo.org/record/10114794
Additional file 1: of Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial
Creators: name: Stockley, Tracy
name: Oza, Amit
name: Berman, Hal
name: Leighl, Natasha
name: Knox, Jennifer
name: Shepherd, Frances
name: Chen, Eric
name: Krzyzanowska, Monika
name: Neesha Dhani
name: Joshua, Anthony
name: Ming-Sound Tsao
name: Serra, Stefano
name: Clarke, Blaise
name: Roehrl, Michael
name: Zhang, Tong
name: Mahadeo Sukhai
name: Califaretti, Nadia
name: Mateya Trinkaus
name: Shaw, Patricia
name: Kwast, Theodorus Van Der
name: Wang, Lisa
name: Virtanen, Carl
name: Kim, Raymond
name: Albiruni Razak
name: Hansen, Aaron
name: Yu, Celeste
name: Pugh, Trevor
name: Kamel-Reid, Suzanne
name: Siu, Lillian
name: Bedard, Philippe
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplementary methods and Tables S1â  S4. (DOCX 148 kb)
Tomocerus Nicolet 1842
Creators: name: Gong, Xin
name: Qin, Chunyan
name: Yu, Daoyuan
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Tomoceridae
Tomocerus

description: Genus Tomocerus Nicolet, 1842
Common characters for the two new species. PAO absent. Eyes 6+6. Both dorsal and ventral sides of head scaled. Mouthparts normal for Tomocerus. Labral formula 4/5, 5, 4, distal edge of labrum with 4 papillae ending in curved spines. Mentum with 5 chaetae, submentum with numerous chaetae. Mandibular head asymmetrical, the left side with 4 teeth and the right side with 5 teeth, left molar plate distally with a tapered tooth. Maxillary lamella 5 without beard-like appendage. Maxillary outer lobe with trifurcate palp, one basal chaeta and 4 sublobal hairs. Both dorsal and ventral sides of Ant. I and Ant. II scaled, Ant. IV unscaled. Macrochaetae densely arranged along anterior margin of Th. II and sparsely on each terga, most mesochaetae laterally and posteriorly on terga. Bothriotricha 2 (a6, m6), 1 (m6)/ 0, 0, 1 (a5), 2 (a2, a5), 0, 0 on Th. II – Abd. VI. Tergal pseudopores 1, 1/ 1, 1, 1, 1, 0, 0 from Th. II to Abd. VI near body axis. Each tibiotarsus with distal whorl of 11 chaetae, ventral 6 as ordinary chaetae, dorsal 5 modified as a central clavate tenent hair, a pair of short accessory chaetae and a pair of slender guard chaetae. Rami of tenaculum with 4+4 teeth. Dens basally without outer strong chaetae or inner large differentiated scales. Dental spines compound, with numerous secondary denticles on surface. Dens dorsally with ordinary chaetae and plumose chaetae, ventrally with dense scales and several apical chaetae. Mucro elongated, bearing numerous chaetae with elongated sockets (not shown in figures); apical tooth subequal to subapical tooth; two dorsal lamellae running from proximal edge of subapical tooth, outer lamella ending in distal edge of inner basal tooth, inner lamella ending at base of mucro, intermediate teeth located on outer lamella; both basal teeth with proximal lamellae, outer basal tooth with toothlet.
description: Published as part of Gong, Xin, Qin, Chunyan & Yu, Daoyuan, 2018, Two new species of Tomocerus ocreatus group with a single large distal dental spine (Collembola, Tomoceridae), pp. 273-282 in Zootaxa 4514 (2) on page 275, DOI: 10.11646/zootaxa.4514.2.10, http://zenodo.org/record/2607838
MOESM1 of A potential role for protein palmitoylation and zDHHC16 in DNA damage response
Creators: name: Cao, Na
name: Jia-Kai Li
name: Rao, Yu-Qing
name: Huijuan Liu
name: Wu, Ji
name: Baojie Li
name: Peiquan Zhao
name: Zeng, Li
name: Li, Jing
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology

description: Additional file 1: Figure S1. 2BP inhibited protein palmitoylation in MEFs. Figure S2. The effect of 2BP on zDHHC gene expression in MEFs. Figure S3. The effect of 2BP and Dox on MEF cell survival. Figure S4. Overexpressed zDHHC16 increased protein palmitoylation in MEFs and was translocated into the nucleus in response to Dox.
Heissiella dryadis
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Heissiella
Heissiella dryadis

description: Heissiella dryadis (DRAKE & POOR, 1936) exld
I N D I n d i e n: Kishtwar/ Sonder, 2 Ex., 5. VII. 1980, leg. Aspöck H.& U., Rausch H.& R.
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 110, DOI: 10.5281/zenodo.7507194
Residual Hyperbolic Graph Convolution Networks
Creators: name: Xue, Yangkai
name: Dai, Jindou
name: Lu, Zhipeng
name: Wu, Yuwei
name: Jia, Yunde
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Hyperbolic graph convolutional networks (HGCNs) have demonstrated representational capabilities of modeling hierarchical-structured graphs. However, as in general GCNs, over-smoothing may occur as the number of model layers increases, limiting the representation capabilities of most current HGCN models. In this paper, we propose residual hyperbolic graph convolutional networks (R-HGCNs) to address the over-smoothing problem. We introduce a hyperbolic residual connection function to overcome the over-smoothing problem, and also theoretically prove the effectiveness of the hyperbolic residual function. Moreover, we use product manifolds and HyperDrop to facilitate the R-HGCNs. The distinctive features of the R-HGCNs are as follows: (1) The hyperbolic residual connection preserves the initial node information in each layer and adds a hyperbolic identity mapping to prevent node features from being indistinguishable. (2) Product manifolds in R-HGCNs have been set up with different origin points in different components to facilitate the extraction of feature information from a wider range of perspectives, which enhances the representing capability of R-HGCNs. (3) HyperDrop adds multiplicative Gaussian noise into hyperbolic representations, such that perturbations can be added to alleviate the over-fitting problem without deconstructing the hyperbolic geometry. Experiment results demonstrate the effectiveness of R-HGCNs under various graph convolution layers and different structures of product manifolds.
A novel rabbit derived anti-HER2 antibody with pronounced therapeutic effectiveness on HER2-positive breast cancer cells in vitro and in humanized tumor mice (HTM)
Creators: name: Wege, Anja K.
name: Kirchhammer, Nicole
name: Kazandjian, Linda Veronique
name: Prassl, Sandra
name: Brandt, Michael
name: Piendl, Gerhard
name: Ortmann, Olaf
name: Fischer, Stephan
name: Brockhoff, Gero
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: ANTITUMOR-ACTIVITY; HER2 EXPRESSION; IMMUNE-RESPONSE; TRASTUZUMAB; PERTUZUMAB; COMBINATION; RESISTANCE; MECHANISM; HERCEPTIN; SK-BR-3; Anti-HER2 antibody; Breast cancer; Treatment efficiency; Humanized tumor mice; Monoclonal antibody
subject: 610 Medizin

description: Background Antibody based cancer therapies have achieved convincing success rates combining enhanced tumor specificity and reduced side effects in patients. Trastuzumab that targets the human epidermal growth factor related receptor 2 (HER2) is one of the greatest success stories in this field. For decades, trastuzumab based treatment regimens are significantly improving the prognosis of HER2-positive breast cancer patients both in the metastatic and the (neo-) adjuvant setting. Nevertheless, >= 50% of trastuzumab treated patients experiencede-novoor acquired resistance. Therefore, an enhanced anti-HER2 targeting with improved treatment efficiency is still aspired. Methods Here, we determined cellular and molecular mechanisms involved in the treatment of HER2-positive BC cells with a new rabbit derived HER2 specific chimeric monoclonal antibody called "B100 ''. We evaluated the B100 treatment efficiency of HER2-positive BC cells with different sensitivity to trastuzumab both in vitro and in the presence of a human immune system in humanized tumor mice. Results B100 not only efficiently blocks cell proliferation but more importantly induces apoptotic tumor cell death. Detailed in vitro analyses of B100 in comparison to trastuzumab (and pertuzumab) revealed equivalent HER2 internalization and recycling capacity, similar Fc receptor signaling, but different HER2 epitope recognition with high binding and treatment efficiency. In trastuzumab resistant SK-BR-3 based humanized tumor mice the B100 treatment eliminated the primary tumor but even more importantly eradicated metastasized tumor cells in lung, liver, brain, and bone marrow. Conclusion Overall, B100 demonstrated an enhanced anti-tumor activity both in vitro and in an enhanced preclinical HTM in vivo model compared to trastuzumab or pertuzumab. Thus, the use of B100 is a promising option to complement and to enhance established treatment regimens for HER2-positive (breast) cancer and to overcome trastuzumab resistance. Extended preclinical analyses using appropriate models and clinical investigations are warranted.