cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Lyn regulates drug resistance mechanisms in chronic myelogenous leukemia (CML)
Creators: name: Okumu, Denis
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Acquired resistance to anti-cancer therapy presents a critical challenge to effective clinical management of chronic myelogenous leukemia (CML).  Drug-resistant CML cells devise diverse molecular adaptations to evade therapy.  Examples of such adaptations include: target (Bcr-Abl) mutations that eliminate drug binding, target amplification, up-regulation of drug exporter proteins, and activation of alternative kinase(s).  The CML cell (Myl-R) model described in this dissertation is a classic example of how CML cells can activate alternative kinase(s) to promote cell survival.  Herein, I discuss two molecular adaptations regulated by Lyn in Myl-R cells.
           In the first project, I showed that increased Lyn expression and activity in Myl-R cells up-regulated the expression and stability of BIRC6, a member of the inhibitor of apoptosis proteins (IAP) family known to bind and inactivate active caspases.  BIRC6’s role in promoting imatinib resistance was confirmed by the 15-fold increase in imatinib sensitivity upon BIRC6 shRNA knockdown.  Pharmacological or genetic inhibition of Lyn reduced BIRC6 expression and stability.  Further, BIRC6 stability was increased via Lyn-dependent phosphorylation of serine residues in a region that overlapped with caspase cleavage motifs.  Pharmacological inhibition of Lyn resulted in caspase-mediated degradation of BIRC6.
           In the second project, I am investigating Lyn’s role in regulating creatine uptake by Myl-R cells.  Our lab previously showed that total intracellular creatine pool was 5-fold higher in Myl-R than Myl cells.  Our unpublished data show that the increased intracellular creatine comes from uptake from the cell culture media and not de novo synthesis.  I, therefore, investigated the role of creatine in Myl-R cells by incubating the cells in normal growth media into which competitive inhibitors of creatine uptake were added. Our data show that reduction in total intracellular creatine pool lowered cell viability.  Others previously showed that the Na+/K+-ATPase pump activity was critical for creatine uptake.  Our data show that Lyn inhibition or shRNA knockdown reduced Na+/K+-ATPase activity and total intracellular creatine pool, suggesting a tripartite signaling cascade that supports Myl-R cell survival.
           Taken together, these studies enrich our understanding of the diverse therapy-survival mechanisms utilized by CML cells, and provide insights into novel targets for effective cure of CML.
Lo que me enseñaron los niños del maestro José Antonio Fernández Bravo organizado por BVVA.
Creators: name: Gonzales, Deyvi Gomez
Publisher: name: Zenodo
Year: 2023
Subjects: enseñanza, personalidad, valores, virtudes

description: Lo que me enseñaron los niños del maestro José Antonio Fernández Bravo organizado por BVVA. Esta reseña se analiza la opinion de José Antonio Fernández Bravo, doctor en Ciencias de la Educación, investigador y escritor, cuenta con tres maestrías sobre lógica, formación del profesorado y diseño educacional. Su pensamiento educativo se alimenta a partes iguales de amor y de humor. El vídeo cuenta con una duración de 2 horas aproximadamente donde se relata la experiencia educativa de más de tres décadas del ponente.
description: {"references": ["degosax25@gmail.com"]}
Long-Term Archiving of (Biodiversity-Related) Data at the Archives of the Bavarian State
Creators: name: Schwartz, Anna Lisa
name: Schmalzl, Markus
Publisher: name: Zenodo
Year: 2023
Subjects: long-term archiving
biodiversity data
NFDI
research data management
NFDI4Biodiversity
SIARD
archive
long-term preservation

description: Presentation on the challenges for long-term archiving within the State Archives of Bavaria and a use case within NFDI4Biodiversity, between the General Directorate of the State Archives and the Bavarian Natural History Collections for the long-term archiving of a dataset (The Erysiphales Collection) and the associated database structure (Diversity Workbench) using the SIARD software of the Swiss Federal Archives. The (virtual) presentation took place as part of the EU COST Action CA17106 on ‘Mobilising Data, Experts and Policies in Scientific Collections’ of the WG4 Workshop: Completing editorial work on the ‘Guideline for long-term preservation and archiving of data products from scientific collections facilities’ in Munich, Bavarian Natural History Collections (January 12-14, 2023).
The Russians Have Been Listening to Us
Creators: name: Korepin, Serguei
Publisher: name: University of North Carolina at Chapel Hill Graduate School
Year: 2015
Subjects: subject: Civilization, Slavic--Study and teaching
subject: Political science
subject: FOS: Political science

description: This thesis shows that there is a correlation between Russians’ perception of the United States and their opinion of democracy. Moreover, it shows that Russians’ perception of the US are, in part, determinative of their opinion of democracy. How and why Russians have formed an association between the US and democracy is also analyzed. This thesis argues that this association was formed because of Russians resilient Soviet identity (including nostalgia), due to social modernization emanating from the US, conditioning via a poor experience with US-associated democracy in the early 1990s, as well as Kremlin and US reinforcement of the US=democracy association.
A Synergistic Kalman- and Deep Postfiltering Approach to Acoustic Echo Cancellation
Creators: name: Haubner, Thomas
name: Halimeh, Mhd. Modar
name: Brendel, Andreas
name: Kellermann, Walter
Publisher: name: arXiv
Year: 2020
Subjects: subject: Audio and Speech Processing (eess.AS)
subject: Sound (cs.SD)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: We introduce a synergistic approach to double-talk robust acoustic echo cancellation combining adaptive Kalman filtering with a deep neural network-based postfilter. The proposed algorithm overcomes the well-known limitations of Kalman filter-based adaptation control in scenarios characterized by abrupt echo path changes. As the key innovation, we suggest to exploit the different statistical properties of the interfering signal components for robustly estimating the adaptation step size. This is achieved by leveraging the postfilter near-end estimate and the estimation error of the Kalman filter. The proposed synergistic scheme allows for rapid reconvergence of the adaptive filter after abrupt echo path changes without compromising the steady state performance achieved by state-of-the-art approaches in static scenarios.
description: Accepted for European Signal Processing Conference (EUSIPCO), Dublin, Ireland, August 2021
CB1 Receptor Activity Modulates Responses in the Forced Swim Test and Open Field Test Paradigms
Creators: name: Culmer, Tyechia L.
Publisher: name: University of North Carolina at Chapel Hill
Year: 2010

description: Cannabinoid type I (CB1) receptor activation in the forced swim test (FST) and on locomotor activity (LMA) was examined by manipulating the endogenous agonist anandamide (AEA). AEA modifier URB597 prevents AEA metabolism and AM404 inhibits the reuptake of AEA in post synaptic neurons. Antidepressant-like behavior was measured using time spent immobile (sec) in the FST, and distance traveled (cm), average velocity (cm/sec), entries into the center zone (#), and time spent in the center zone (min) in the open field test. LMA before (Pre-FST1), immediately after (Post-FST1), and a week after the FST (LMA-FST1) were measured. Time spent immobile decreased with desipramine (DMI; 10 mg/kg), URB597 (1.0 and 3.2 mg/kg), and AM404 (1.0 mg/kg). Although 1.0 mg/kg of URB597 and AM404 reduced time spent immobile, distance traveled was not impaired. Overall, the decreases in time spent immobile were not because of LMA solely, and URB597 and AM404 have antidepressant properties.
Explicit formulation of second and third order optical nonlinearity in the FDTD framework
Creators: name: Varin, Charles
name: Emms, Rhys
name: Bart, Graeme
name: Fennel, Thomas
name: Brabec, Thomas
Publisher: name: arXiv
Year: 2016
Subjects: subject: Optics (physics.optics)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The finite-difference time-domain (FDTD) method is a flexible and powerful technique for rigorously solving Maxwell's equations. However, three-dimensional optical nonlinearity in current commercial and research FDTD softwares requires solving iteratively an implicit form of Maxwell's equations over the entire numerical space and at each time step. Reaching numerical convergence demands significant computational resources and practical implementation often requires major modifications to the core FDTD engine. In this paper, we present an explicit method to include second and third order optical nonlinearity in the FDTD framework based on a nonlinear generalization of the Lorentz dispersion model. A formal derivation of the nonlinear Lorentz dispersion equation is equally provided, starting from the quantum mechanical equations describing nonlinear optics in the two-level approximation. With the proposed approach, numerical integration of optical nonlinearity and dispersion in FDTD is intuitive, transparent, and fully explicit. A strong-field formulation is also proposed, which opens an interesting avenue for FDTD-based modelling of the extreme nonlinear optics phenomena involved in laser filamentation and femtosecond micromachining of dielectrics.
description: Final version published in Computer Physics Communications
Fracture Resistance of ProTaper UltimateTM Files Under Simulated Clinical Conditions
Creators: name: Park, Sue Bin
Publisher: name: University of Illinois at Chicago
Year: 2023

description: The objective of this study is to compare Torsional Force to Fracture (TFF) of ProTaper UltimateTM (PTU) Nickel-Titanium (NiTi) rotary instruments in as-received condition, after 1 and 3 simulated clinical uses in Endo-training blocs (ETB) and 3D printed teeth (3DT), respectively. Materials and Methods: A total of 5 sets of PTU NiTi files were used in simulated root canals (30-degree curvature) in ETB and 3DT per manufacturer instructions. File sets consisted of Slider (SL), Shaper (SH), F1, F2 and F3 files 25mm in length (N=5/size/group). Later, the mechanical properties of the files were evaluated according to ISO 3630-1 guidelines using a Torsiometer. (Sabri Dental Enterprises, Inc, Downers Grove, IL). For each tested file, measurements of peak torque (gm-cm) and angle rotation (°) were documented. The collected data was subjected to analysis using ANOVA and Tukey-Kramer tests (p<.05). Results: Peak torque was significantly lower after instrumentation of ETB compared to 3DT for SL and SH files (p<.05). There were no statistically significant differences in TFF in all simulated clinical conditions for F1, F2 and F3 files. For all files in all simulated clinical conditions, no statistically significant changes were observed in angle rotation. Conclusions: TFF of PTU NiTi rotary files decreased after use in ETB compared to 3DT. Within the limitations of this study, these findings may indicate a greater role of clinical conditions such as canal curvature and hardness rather than the number of uses (within 3 times).
Was haben Mehltaupilze mit digitaler Langzeitarchivierung zu tun?
Creators: name: Weibulat, Tanja
name: Schwartz, Anna Lisa
name: Seifert, Stefan
name: Schmalzl, Markus
name: Triebel, Dagmar
Publisher: name: Zenodo
Year: 2023
Subjects: Langzeitarchivierung
NFDI
Forschungsdatenmanagement
SIARD
NFDI4Biodiversity
Archiv

description: Vorstellung eines NFDI4Biodiversity-Kooperationsprojekts zwischen der Generaldirektion der staatlichen Archive Bayerns (GDA) und den Staatlichen Naturwissenschaftlichen Sammlungen Bayerns (SNSB) über die Langzeitarchivierung einer Datenbank der SNSB zum Management der Sammlung von Mehltaupilz-Objekten.
REGIONAL AND NATIONAL IDENTITIES IN JOSÉ ROLÓN'S EL FESTÍN DE LOS ENANOS AND ZAPOTLÁN
Creators: name: Madrid, David Rogelio Guevara
Publisher: name: Zenodo
Year: 2023
Subjects: Rolón
nationalism
regionalism
Jalisco
Zapotlán
Ponce

description: During the efforts in Mexico in the early twentieth century to craft a national musical identity, several leading figures debated how composers should proceed in order to advance Mexican musical arts. Scholars such as Leonora Saavedra, Alejandro Madrid, and Ricardo Miranda have examined the many ideas concerning Mexican national musical identity that were presented during the First National Congress of Music in 1926, as well as in national publications and in the works of the prominent Mexican composers who participated in that seminal congress. To understand how these ideas contributed to the development of Mexican musical nationalism, I examine José Rolón’s orchestral works El festín de los enanos and Zapotlán for their connections to the ideals of the First National Congress of Music. El festín de los enanos was awarded first prize in the folk-symphonic poem category at that congress, and the work included some musical ideas that were later expanded upon in Zapotlán. As Miranda has noted, some of Rolón’s compositions utilize Mexican sones (folk tunes) and canciones (lyric songs) found in Rubén M. Campos’s often-cited 1928 book El folklore y la música mexicana, and this usage links his works to a form of musical nationalism rooted in folk materials. By analyzing formal structures, melodic source material, and orchestration techniques in El festín de los enanos and Zapotlán, I argue that these two compositions demonstrate Rolón’s significance as an early nationalist composer.
LOW EMISSIONS, HIGH CONCERN: HOW CLIMATE COMMUNICATORS GRAPPLE WITH A TRANSNATIONAL ISSUE IN THE PHILIPPINES
Creators: name: Evans, Suzannah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Climate change is one of the most pressing scientific and social issues of the 21st century. Communication about climate change has been the subject of intense interest by social scientists for the last two decades. However, the vast majority of scholarly studies about climate communication have focused on the wealthy nations that are major carbon polluters. Little is known about how climate change is communicated in the poorer nations that produce few emissions and are the first to experience the effects of climate change. This study addresses that gap in in scholarship by focusing on climate communication in the Philippines, a developing nation where climate change has been on the national agenda since increasingly devastating typhoons struck the country in the last five years. The study uses a mixed-methods design that includes semi-structured interviews and a quantitative social media analysis. Climate activists and journalists were interviewed in Manila to understand three aspects of climate communication in the developing world: journalists’ climate reporting, and activists’ social movement frame-building as well as social media strategies. A quantitative analysis of social media strategies was conducted on activist messages on Twitter targeting the U.N. climate negotiations in Paris in December 2015. This mixed-methods study of three aspects of climate communication in the developing world is informed by theories from mass communication and social movement scholarship. In particular, the study is concerned with public sphere theory and its applicability to a transnational issue – climate change – and the advent of borderless digital media systems. In general, the study finds that climate communicators in the developing world continue to be disempowered in the global debate about emissions despite the rise of global forms of journalism and open-access digital media networks. Climate journalism is still nascent and reporters struggle to connect local effects of climate change to the global issue due to organizational and cultural constraints. Activists are better-positioned to engage with climate on a transnational scale; they do this through the climate justice frame and in their social media strategies. However, developing nation voices still struggle to be heard as they compete with a multitude of other actors even in the supposedly democratic networked media space.
Versatile Approach to the Spin Dynamics in Correlated Electron Systems
Creators: name: Behrmann, Malte
name: Lichtenstein, Alexander I.
name: Katsnelson, Mikhail I.
name: Lechermann, Frank
Publisher: name: arXiv
Year: 2016
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Time-dependent spin phenomena in condensed matter are most often either described in the weakly correlated limit of metallic Stoner/Slater-like magnetism via band theory or in the strongly correlated limit of Heisenberg-like interacting spins in an insulator. However many experimental studies, e.g. of (de)magnetization processes, focus on itinerant local-moment materials such as transition metals and various of their compounds. We here present a general theoretical framework that is capable of addressing correlated spin dynamics, also in the presence of a vanishing charge gap. A real-space implementation of the time-dependent rotational-invariant slave boson methodology allows to treat non-equilibrium spins numerically fast and efficiently beyond linear response as well as beyond the band-theoretical or Heisenberg limit.
description: 9 pages, 7 figures, revised version
UN Food Systems Summit 2021 – What Role Science and Innovation in the Summit and in Countries’ Plans and Why?
Creators: name: Von Braun, Joachim
name: Von Braun, Joachim
Publisher: name: Unknown
Year: 2023
Subjects: subject: Food Security and Poverty
subject: Research and Development/Tech Change/Emerging Technologies
subject: economic development
subject: food system
subject: agriculture
subject: governance
subject: United Nations
subject: science
subject: innovation
subject: technology

description: The UN Food Systems Summit 2021 was different from all six previous food summits held in the past eight decades. New features of this Summit included the fact that it was anchored in the Sustainable Development Goals, focused on food systems, was based on multi-stakeholder engagement, had a focus on country level strategies (so called National Pathways), and the Summit was held in New York rather than Rome, where the UN food agencies are based. Moreover, for the first time the UN called upon science to provide guidance for a food summit. In this article outcomes and political economy processes of the Summit are briefly reviewed, and then a focus is on the role of science for shaping outcomes is quantitatively assessed by reviewing the 118 country reports of National Pathways. In 62% of the countries’ strategies science, research, technology and innovation are more or less significantly mentioned. Quality of governance effectiveness is identified as a strong driver of more attention to science in countries’ strategies. The relative weight of agriculture in the national economy shows some positive correlation with attention to science too, whereas level of undernutrition does not correlate with attention to science in the strategies. Implications of these findings are drawn for the science – policy interface in food systems, and for the follow-up process to the Summit that has been put in place by the UN until 2030.
Women in Science: Disaggregating Between- and Within-Person Effects Using a Novel Modeling Framework
Creators: name: Burfeind, Chelsea
Publisher: name: University of North Carolina at Chapel Hill Graduate School
Year: 2015
Subjects: subject: Psychometrics
subject: Psychology
subject: FOS: Psychology
subject: Quantitative research

description: Extant research indicates that females are less likely than males to pursue a degree in the fields of science, technology, engineering, and math (STEM), despite equal achievement in the subjects. This project aimed to examine the longitudinal relationship between interest and achievement in math in adolescents while implementing a novel modeling framework. The residualized autoregressive latent trajectory (RALT) was implemented to completely disaggregate between-and within-person effects, and a multiple-group model was utilized to test for gender differences in the RALT parameters. Males and females were shown to differ at the between-person level, with females reporting higher levels of math achievement and lower levels of interest in math than males. Within-person effects were not shown to vary systematically by gender. This project provided a thorough analysis of a substantive topic through the use of a new modeling framework.
Dynamical Properties of Some Non-stationary, Non-simple Bratteli-Vershik Systems
Creators: name: Bailey, Sarah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Bratteli-Vershik systems, also called adics, are dynamical systems defined on the infinite path space of a Bratteli diagram. We introduce a family adics called limited scope adics for which the number of vertices increases by a constant at each level, and a subfamily determined by positive integer polynomials. We show that the dimension groups of the Bratteli diagrams associated to limited scope adics are intrinsically linked to the dynamics, generalizing a result for Cantor minimal systems, and we explicitly compute them for the subfamily of adics determined by a positive integer polynomials. We show that certain limited scope adics are isomorphic to subshifts. For the systems determined by positive integer polynomials we show that the set of fully-supported invariant ergodic probability measures consists of a one-parameter family of Bernoulli measures. We also show that the systems associated to positive integer polynomials are loosely Bernoulli. A particular limited scope adic system is the Euler adic system, for which the number of paths from the root vertex to a vertex (n,k) is the Eulerian number A(n,k). We show that this system has a unique fully-supported invariant ergodic probability measure and that the system is totally ergodic and loosely Bernoulli.
1/r potential in higher dimensions
Creators: name: Chakraborty, Sumanta
name: Dadhich, Naresh
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In Einstein gravity, gravitational potential goes as $1/r^{d-3}$ in $d$ non-compactified spacetime dimensions, which assumes the familiar $1/r$ form in four dimensions. On the other hand, it goes as $1/r^α$, with $α=(d-2m-1)/m$, in pure Lovelock gravity involving only one $m$th order term of the Lovelock polynomial in the gravitational action. The latter offers a novel possibility of having $1/r$ potential for the non-compactified dimension spectrum given by $d=3m+1$. Thus it turns out that in the two prototype gravitational settings of isolated objects, like black holes and the universe as a whole --- cosmological models, the Einstein gravity in four and $m$th order pure Lovelock gravity in $3m+1$ dimensions behave in a similar fashion as far as gravitational interactions are considered. However propagation of gravitational waves (or the number of degrees of freedom) does indeed serve as a discriminator because it has two polarizations only in four dimensions.
description: 8 pages, no figures; Revised version, title changed;
A cortical-inspired sub-Riemannian model for Poggendorff-type visual illusions
Creators: name: Baspinar, Emre
name: Calatroni, Luca
name: Franceschi, Valentina
name: Prandi, Dario
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Differential Geometry (math.DG)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: We consider Wilson-Cowan-type models for the mathematical description of orientation-dependent Poggendorff-like illusions. Our modelling improves two previously proposed cortical-inspired approaches embedding the sub-Riemannian heat kernel into the neuronal interaction term, in agreement with the intrinsically anisotropic functional architecture of V1 based on both local and lateral connections. For the numerical realisation of both models, we consider standard gradient descent algorithms combined with Fourier-based approaches for the efficient computation of the sub-Laplacian evolution. Our numerical results show that the use of the sub-Riemannian kernel allows to reproduce numerically visual misperceptions and inpainting-type biases in a stronger way in comparison with the previous approaches.
Avaliação externa de escolas: políticas e lideranças no desenvolvimento de uma escola inclusiva
Creators: name: Silva, Jennifer
Publisher: name: Zenodo
Year: 2023
Subjects: Avaliação externa de escolas, políticas inclusivas, lideranças, avaliação realista, imagens organizacionais da escola

description: Neste projeto de investigação, pretende-se compreender de que forma as lideranças (de topo e intermédias) de um Agrupamento de Escolas da rede pública de Portugal continental, avaliado pela Inspeção-Geral da Educação e Ciência (IGEC), no atual terceiro ciclo avaliativo do Programa de Avaliação Externa das Escolas (PAEE), concretizam os princípios orientadores da educação inclusiva, de acordo com as políticas educativas vigentes. A Teoria da Avaliação Realista estará na base do enquadramento teórico e metodológico deste projeto. Para o efeito, pretende-se realizar um estudo de caso, inserindo-se a investigação no paradigma interpretativo de natureza qualitativa.
 Através da análise documental e de inquéritos por entrevistas semiestruturadas, procurar-se-á, junto de elementos das lideranças da escola, identificar efeitos da avaliação externa na consecução de melhorias, ao nível do planeamento, da gestão e da ação educativa.
 Serão identificadas as imagens organizacionais de escola que poderão estar associadas ao contexto de avaliação institucional.
Divergence Regulated Encoder Network for Joint Dimensionality Reduction and Classification
Creators: name: Peeples, Joshua
name: Walker, Sarah
name: McCurley, Connor
name: Zare, Alina
name: Keller, James
name: Xu, Weihuang
Publisher: name: arXiv
Year: 2020
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Feature representation is an important aspect of remote-sensing based image classification. While deep convolutional neural networks are able to effectively amalgamate information, large numbers of parameters often make learned features inscrutable and difficult to transfer to alternative models. In order to better represent statistical texture information for remote-sensing image classification, in this paper, we investigate performing joint dimensionality reduction and classification using a novel histogram neural network. Motivated by a popular dimensionality reduction approach, t-Distributed Stochastic Neighbor Embedding (t-SNE), our proposed method incorporates a classification loss computed on samples in a low-dimensional embedding space. We compare the learned sample embeddings against coordinates found by t-SNE in terms of classification accuracy and qualitative assessment. We also explore use of various divergence measures in the t-SNE objective. The proposed method has several advantages such as readily embedding out-of-sample points and reducing feature dimensionality while retaining class discriminability. Our results show that the proposed approach maintains and/or improves classification performance and reveals characteristics of features produced by neural networks that may be helpful for other applications.
description: 8 pages (5 main pages and 3 supplemental pages), 2 figures, accepted to IEEE Geoscience and Remote Sensing Letters
NEUROCOGNITVE AND BALANCE PERFORMANCE FOLLOWING A DUAL-TASK AND SINGLE-TASK TRAINING INTERVENTION IN HEALTHY COLLEGIATE RECREATIONAL ATHLETES
Creators: name: Ingriselli, Joseph Marc
Publisher: name: University of North Carolina at Chapel Hill
Year: 2012

description: The purpose of this study was to examine neurocognitive and balance performance in healthy collegiate recreational athletes, prior to and following a dual-task (DT) training intervention compared to matched single-task (ST) controls. Thirty healthy, physically active college aged participants completed neurocognitive and balance assessments prior to and following a four-week training intervention. The single task group showed significantly greater improvement following their four-week training period compared to the dual-task group (F1,26=5.478, p= 0.027). Both groups significantly improved neurocognitive domains of complex attention (F1,26=6.726, p=0.015), executive function (F1,28 = 4.968, p= 0.034), cognitive flexibility(F1,28 = 6.707, p= 0.015), SOT Vestibular ratio scores (F1,28=6.550, p=0.016) and significantly reduced the number of errors committed during the BESS (F1,26=42.342, p<.000) following the interventions. Our findings suggest that combining a cognitive task with a balance task did not have any additional benefits to performing these tasks independently.
MPEC 2023-Q54 : 2023 QM1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 QM1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Non-dipolar Wilson links for quasi-parton distribution functions
Creators: name: Li, Hsiang-nan
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose a modified definition for a quasi-parton distribution function (QPDF) with an equal-time correlator in the large momentum limit, whose two pieces of space-like Wilson links are oriented in orthogonal directions. It is explicitly shown at one-loop level that the linear divergence in the original QPDF with dipolar Wilson links, which complicates its matching to the standard light-cone parton distribution function (LPDF), is removed. The LPDF can then be extracted reliably from Euclidean lattice data for the QPDF with the non-dipolar Wilson links.
description: 7 pages, 2 figures
Intracortical Inputs to Neurons in Layer 4 of Primary Auditory Cortex
Creators: name: Kratz, Megan
Publisher: name: University of North Carolina at Chapel Hill
Year: 2012

description: Primary auditory cortex (A1) is organized tonotopically. However, individual neurons in A1 respond to a wider range of sound frequencies than would be predicted by their thalamic inputs, which suggests the existence of cross-frequency intracortical inputs. We use photostimulation in slices of mouse A1 that contain the entire tonotopic map to identify cross-frequency intracortical inputs to Layer 4 (L4) neurons. We find that L4 neurons receive intracortical inputs from L4 and L6 neurons in columns ~300 μm caudal and/or rostral to the cell, in addition to local columnar input. These lateral inputs are most likely tuned to different frequencies than the neuron that receives them. This result suggests that L4 neurons receive inputs that have a harmonic relationship to their best frequencies. These lateral connections may be part of a circuit that allows A1 to detect auditory objects with specific harmonic structure.
Integer homology 3-spheres admit irreducible representations in SL(2,C)
Creators: name: Zentner, Raphael
Publisher: name: arXiv
Year: 2016
Subjects: subject: Geometric Topology (math.GT)
subject: Differential Geometry (math.DG)
subject: Group Theory (math.GR)
subject: Representation Theory (math.RT)
subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics
subject: 57R57

description: We prove that the fundamental group of any integer homology 3-sphere different from the 3-sphere admits irreducible representations of its fundamental group in SL(2,C). For hyperbolic integer homology spheres this comes with the definition, and for Seifert fibered integer homology spheres this is well known. We prove that the splicing of any two non-trivial knots in the 3-sphere admits an irreducible SU(2)-representation. By work of Boileau, Rubinstein, and Wang, the general case follows. Using a result of Kuperberg, we get the corollary that the problem of 3-sphere recognition is in the complexity class coNP, provided the generalised Riemann hypothesis holds. To prove our result, we establish a topological fact about the image of the SU(2)-representation variety of a non-trivial knot complement into the representation variety of its boundary torus, a pillowcase. For this, we use holonomy perturbations of the Chern-Simons function in an exhaustive way - we show that any area-preserving self-map of the pillowcase fixing the four singular points, and which is isotopic to the identity, can be C^0-approximated by maps which are realised geometrically through holonomy perturbations of the flatness equation in a thickened torus. To conclude, we use a stretching argument in instanton gauge theory, and a non-vanishing result of Kronheimer and Mrowka for Donaldson's invariants of a 4-manifold which contains the 0-surgery of a knot as a splitting hypersurface.
description: 58 pages, 2 figures; v2: a few typos corrected; v3: results of section 10 strengthened, results about the complexity of 3-recognition added, outline of the technical main result added to the introduction, updated acknowledgements and references; v4: revision after two referee reports, to appear in Duke Math. J
Das sinnsuchende Individuum
Creators: name: Sun, Yun-Ping
Publisher: name: Humboldt-Universität zu Berlin, Philosophische Fakultät I
Year: 2004
Subjects: subject: Individuum
subject: Nichts
subject: Metaphysik
subject: Religionsphilosophie
subject: Individual
subject: Nothingness
subject: Metaphysics
subject: Philosophie of religion.
subject: 100 Philosophie
subject: 10 Philosophie
subject: CI 2617

description: Heideggers Philosophie erweist sich als die Suche nach dem Lebenssinn. Es geht ihm darum, wie der Einzelmensch sein eigenes Leben als ein sinnvolles Ganzes gestalten und führen soll. Es kommt dabei darauf an, ob das Individuum sich von der Masse befreien und mit dem eigenen Tod konfrontieren kann bzw. will. Unter diesen Umständen weist Heidegger auf die Vereinzelung der Person und ihre Erfahrung des Nichts hin. Das Dasein kann sich allein in der Erfahrung des Nichts als Seins vom Seienden als Ganzen abkehren. Sich über das Seiende im Ganzen erheben bedeutet Heidegger zufolge die metaphysische Betrachtungsweise. Die Existenz des Menschen ist für Heidegger genau das metaphysische Phänomen, nämlich unsere Bezugnahme auf die Welt als Ganzes. Diese kontemplative Haltung des Individuums hängt wiederum mit seiner Einstellung zur Gottesauffassung zusammen. Das Verständnis Gottes als eines Seienden führt zum unangemessenen Gottesverhältnis. Gott als das Sein ansehen kann das Gottesverhältnis zurechtsetzen. Die Bedeutung des Lebens erschließt sich erst dann, wenn das Individuum sich seiner Endlichkeit vor Gott als dem Sein bewusst ist.
description: This dissertation argues that the entire Heidegger’s Philosophy amounts to an exploration of the meaning of human life. For him, it is important in life to form and fulfil our own life as an integral whole. It is thus crucial to explore how we can do so, by freeing ourselves, each in our respective individual ways, from the influence of the masses and face resolutely up to our own individual death, by realising each one’s indiviualization and experiencing nothingness. Dasein our inauthentic being-there is dispersed only in the experience of Nothingness as Being per se. For Heidegger, transcendence beyond all entities/beings is the genuine metaphysical way of envisaging them. Human existence is for Heidegger just a metaphysical phenomenon, namely, our point of reference to the world as a whole. This contemlative attitude of the individual is connected further with his views of God. Understanding God as an entity, a mere being, leads to an inappropriate relationship to God, and should be redressed by regarding God as the Being per se. The meaning of life discloses itself only as an individual becomes aware of his/her finiteness before God as the Supreme Being.
Prognostische Bedeutung des p53/Bax/p16 INK4a -Signalwegs bei Patienten mit kolorektalem Karzinom
Creators: name: Schelwies, Katharina
Publisher: name: Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité
Year: 2005
Subjects: subject: Apoptose
subject: p53
subject: Bax
subject: Prognose
subject: apoptosis
subject: bax
subject: prognosis
subject: 610 Medizin
subject: 33 Medizin
subject: XH 7204
subject: XH 7213
subject: XH 7218

description: Die Dysregulation von Zelltod-Signalwegen und die Inaktivierung von Apoptose-Signalwegen ist ein häufiges Ereignis bei der Entstehung maligner Tumore. Ziel dieser dieser Studie war es den prognostischen Wert der Bax- und p16INK4a-Proteinexpression in Korrelation zum Mutationsstatus des p53-Gens bei Patienten in einem Kollektiv von primären kolorektalen Adenokarzinom zu analysieren. Methoden: Retrospektiv wurden 116 Patienten mit einem kolorektalen Karzinom (CRC) im Stadium III und IV nach operativer Therapie und follow-up über 5 Jahre untersucht (UICC Stadium III: 59 Patienten; UICC Stadium IV: 57 Patienten). Die Profile der Bax- und p16INK4a-Proteinexpression wurden mittels Immunhistochemie, die p53-Mutationen (Exon 5 - 8) mittels Single Strand Conformation Polymorphism (SSCP)-PCR untersucht. Die gewonnenen Daten wurden mit klinisch-pathologischen Daten korreliert und statistisch analysiert Ergebnisse: Das mediane Gesamtüberleben betrug 17 Monate. Patienten im Stadium III lebten länger als solche im Stadium IV: 69 vs. acht Monate (p
description: Deregulation of cell death and cell cycle regulation pathways is a frequent event in cancer. Therefore, the purpose of this study was to analyse the prognostic value of Bax and p16INK4a protein expression in correlation to the mutational status of the p53 tumorsuppressor gene in primary colorectal adenocarcinoma. Methods: 116 patients with colorectal adenocarcinoma (CRC) undergoing surgery with curative intention a followed-up for a minimum of five years were analyzed (UICC Stage III: 59 patients, UICC Stage IV: 57 patients). Protein expression profiles of Bax and p16INK4a were analysed by immunhistochemistry, the p53-mutations (exon 5 - 8) by Single-Strand-Conformation-Polymorphism (SSCP)-PCR. Data was correltated with clinical and pathological parameters and analysed statistically. Results: Overall median survival was 17 months. As expected, patients with stage III malignancies survived longer than stage IV patients: 69 months vs. 8 months (p
SOMBI: Bayesian identification of parameter relations in unstructured cosmological data
Creators: name: Frank, Philipp
name: Jasche, Jens
name: Enßlin, Torsten A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: This work describes the implementation and application of a correlation determination method based on Self Organizing Maps and Bayesian Inference (SOMBI). SOMBI aims to automatically identify relations between different observed parameters in unstructured cosmological or astrophysical surveys by automatically identifying data clusters in high-dimensional datasets via the Self Organizing Map neural network algorithm. Parameter relations are then revealed by means of a Bayesian inference within respective identified data clusters. Specifically such relations are assumed to be parametrized as a polynomial of unknown order. The Bayesian approach results in a posterior probability distribution function for respective polynomial coefficients. To decide which polynomial order suffices to describe correlation structures in data, we include a method for model selection, the Bayesian Information Criterion, to the analysis. The performance of the SOMBI algorithm is tested with mock data. As illustration we also provide applications of our method to cosmological data. In particular, we present results of a correlation analysis between galaxy and AGN properties provided by the SDSS catalog with the cosmic large-scale-structure (LSS). The results indicate that the combined galaxy and LSS dataset indeed is clustered into several sub-samples of data with different average properties (for example different stellar masses or web-type classifications). The majority of data clusters appear to have a similar correlation structure between galaxy properties and the LSS. In particular we revealed a positive and linear dependency between the stellar mass, the absolute magnitude and the color of a galaxy with the corresponding cosmic density field. A remaining subset of data shows inverted correlations, which might be an artifact of non-linear redshift distortions.
description: 18 pages, 12 figures, accepted by A&A
Roadblocks Remain: Constraints to Women’s Political Participation and Mobility in Pakistan
Creators: name: Thompson, Sarah
name: Rahman, Natalya
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Comparative Politics
subject: Political Science
subject: FOS: Political science
subject: Social and Behavioral Sciences
subject: gender
subject: mobility
subject: Pakistan
subject: political participation
subject: transportation
subject: voting

description: Pakistan is among the lowest ranked countries in terms of gender parity in political participation. Prior work suggests that Pakistani men and women in the same households differ in their ability to move freely, yet has not directly tested the impacts that transportation environments and freedom of movement have on political participation. In this study we hypothesize and test how mobility constraints may disproportionately decrease women’s political participation. We do so through a phone-based survey experiment in urban areas of Punjab, Pakistan testing how mobility-related constraints like wait times, street safety, and security of polling stations impact men and women’s willingness to engage in formal political processes, and under what conditions. We also provide descriptive evidence that increasing access to mobility can be connected to higher rates of participation as well as political interest, knowledge, and efficacy. These factors have been connected to political participation as well as the potential to express autonomous preferences. Our study holds direct implications for decreasing this gender gap in developing democracies. It also contributes to an emerging literature linking geography and political participation in the unique context of South Asia, where gendered social norms are strong and women’s mobility is low.
Stories from the closet: gender relations and gender identities of trans women in Bogota, Colombia
Creators: name: Hernandez-Losada, Carolina
Publisher: name: La Trobe
Year: 2023

description: Submission note: Thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Department of Social Inquiry, School of Humanities and Social Sciences, College of Arts, Social Sciences and Commerce, La Trobe University, Victoria.
A variational reduction and the existence of a fully-localised solitary wave for the three-dimensional water-wave problem with weak surface tension
Creators: name: Buffoni, Boris
name: Groves, Mark D.
name: Wahlén, Erik
Publisher: name: arXiv
Year: 2016
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 76B15 (Primary) 76B25, 76B45, 35A15 (Secondary)

description: Fully localised solitary waves are travelling-wave solutions of the three-dimensional gravity-capillary water wave problem which decay to zero in every horizontal spatial direction. Their existence has been predicted on the basis of numerical simulations and model equations (in which context they are usually referred to as `lumps'), and a mathematically rigorous existence theory for strong surface tension (Bond number $β$ greater than $\frac{1}{3}$) has recently been given. In this article we present an existence theory for the physically more realistic case $0
description: To appear in Archive for Rational Mechanics and Analysis
ORTA OKULLARDA OKUTULAN 5. ,6. ,7. VE 8. SINIF MATEMATİK DERS KİTAPLARININ İÇERİĞİNDEKİ KÖK DEĞERLERİN İNCELENMESİ
Creators: name: KAZANCI, EDA
Publisher: name: Zenodo
Year: 2023
Subjects: SECANDAY SCHOOL, MATCH BOOKS GRADES

description: Value is the whole of the principles that play a role in shaping the thoughts, attitudes and behaviors of individuals, preparing them for the society they live in and giving them a perspective on the way to become an individual. It is also expressed as criteria that enable individuals to control their behavior (Aydın,2011, p.39). Values education is a concept as old as the concept of education. For centuries, the first purpose of education on earth has been to raise smart people, and the second has been to educate good people. Therefore, values education can be found in societies of all beliefs. The main purpose of values education is to raise citizens with good character, moral values, and awareness of social responsibility by emphasizing the universal values that humanity has in common. Values Education aims to provide important moral and civil values such as love, respect, responsibility, honesty, courage, justice, faith, perseverance, patriotism, cooperation and individual discipline.