cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Amino acid metabolism in Chinese hamster ovary cell culture
Creators: name: Kyriakopoulos, Sarantos
Publisher: name: Imperial College London
Year: 2014

description: The present thesis focuses on amino acids (a.a.) and their metabolism by Chinese hamster ovary cells, the workhorse of the multibillion dollar biopharmaceutical industry. The aim of the research was to explore a.a. transport and metabolism and define optimal operating conditions during fed-batch culture, which is the most common process mode used industrially. A fast and reliable way to calculate a.a. concentration ranges in media and feeds is of vital importance, as a.a. are the monomers of proteins, which account for 70% of dry cell weight. The desired recombinant product of bioprocesses is typically also a protein. The transport of a.a. into the cells was studied at the mRNA level of a.a. transporters for the first time in a bioprocessing context. The presented results demonstrate that a.a. transport is not the limiting step for recombinant protein formation. Also, the study allowed for a staged feeding strategy to be designed, where a.a. were not fed altogether. Following linear projection of an integral of viable cell concentration target and using the specific a.a. consumption rates during batch culture, six feeds were formulated containing a.a. and glucose. Three designs were based on the results of the a.a. transport study; however, they underperformed in comparison to the other feeds. In the latter, all nutrients were fed at the same time, resulting in cell culture performance comparable to that obtained with a commercial feed that was tested in parallel. This renders the presented method the first to define a traceable quantitative way to calculate amount of nutrients in the feeds. Flux balance analysis, a powerful technique that allows for investigation of intracellular dynamics, was used to analyse the metabolic data. An enhanced intracellular network was created by coupling two pre-existing in the literature that also for the first time included the glycosylation of the host proteins in the biomass equation. Finally, a novel methodology was developed and coded in R to calculate specific rates of consumption/production of various metabolites in cell culture. The methodology couples mass balances for fed-batch culture operation with constructed vectors of the sampling and feeding schemes. This can be further developed to a bioprocess relevant software platform for analysing cell culture data.
Chiral Symmetry Breaking and Cooling in Lattice QCD
Creators: name: Woloshyn, R. M.
name: Lee, F. X.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Chiral symmetry breaking is calculated as a function of cooling in quenched lattice QCD. A non-zero signal is found for the chiral condensate beyond one hundred cooling steps, suggesting that there is chiral symmetry breaking associated with instantons. Quantitatively, the chiral condensate in cooled gauge field configurations is small compared to the value without cooling.
description: 11 pages in REVTEX including 4 PS figures embedded using psfig.sty, uuencoded
Hydrophobization and evaluation of absorption capacity of Aloe vera, Opuntia ficus-indica and Gelidium for oil spill cleanup
Creators: name: Cortez, Javier S. Acevedo
name: Kharisov, Boris I.
name: Serrano, Thelma
name: González, Lucy T.
name: Kharissova, Oxana V.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology

description: Natural sorbent materials have practical advantages for the oil spill cleanup, whose advantages are their low-cost, feasibility for real-life applications and environmental adaptability. In this work, absorption capacity was determined for lyophilized aloe, nopal and agar and their composites with silica, Fe3O4/polysterene and multi-wall carbon nanotubes (MWCNTs). Freeze-drying was performed in order to preserve the structure and increase the internal volume of sorbents. The structures of lyophilized sorbents and composites were analyzed by scanning electron microscopy (SEM). SEM images for lyophilized sorbents show a tridimensional arrangement formed by plant-derived materials, which allows the oil absorption. The composites keep their tridimensional structure after freeze-drying and composite formation and exhibit coupling between both materials. Absorption capacity of aloe, nopal and agar are 9 g/g, 3 g/g, and 26 g/g, respectively without any pretreatment. Composites with Fe3O4/polysterene own capacities of 5.8 g/g, 2.8 g/g, and 14 g/g, respectively. Finally, for MWCNT composites, capacities are 7.8 g/g, 2.9 g/g and 23 g/g. A significant difference of adsorption capacity between lyophilized sorbents and composites is attributed to lyophilized materials absorbing oil, water and other compounds. Meanwhile, for composites the absorption is a more selective process, since the hydrophobization does not allow the absorption of water.
Color-color Relations for Red Giants in Star Clusters
Creators: name: von Braun, Kaspar
name: Chiboucas, Kristin
name: Minske, Jocelyn Kelly
name: Salgado, Jose Francisco
name: Worthey, Guy
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: New Johnson-Cousins UBVRI photometry of giants in globular clusters is combined with JHK photometry on the CIT system to produce color sequences for giants from the globular clusters M3, M5, M13, and M92. UBVRI data are also presented for giants in the metal-rich open cluster NGC 6791. These data fill a gap in the literature, especially for the R & I bands. We provide the empirical relations between broad band colors for various [Fe/H] values for metal-poor giants. The color sequences for U-B and B-V show clear separations for different [Fe/H] values. We also find weak, though unexpected, metallicity dependences of V-R, V-I, and J-K colors. H-K is metal-insensitive. The above colors are plotted as a function of V-K, and a literature (V-K) - T_{eff} relation is given.
description: 21 pages, 7 figures; AASTeX 4.0; to appear in the July 1998 edition of PASP. Revised version; includes discussion on possible effects of reddening errors
Spectral Density on the Lattice
Creators: name: Makovoz, D.
name: Miller, G. A.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Spectral density in the pseudoscalar and vector channels is extracted from the SU(2) lattice quenched data. It is shown to consist of three sharp poles within the energy range accessible on the lattice.
description: 38 pages, uuencoded tar-compressed ps-file
HST spatially-resolved spectra of the accretion disc and gas stream of the nova-like variable UX Ursae Majoris
Creators: name: Baptista, R.
name: Horne, K.
name: Wade, R. A.
name: Hubeny, I.
name: Long, K. S.
name: Rutten, R. G. M.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Time-resolved eclipse spectroscopy of the nova-like variable UX UMa obtained with the HST/FOS on 1994 August and November is analyzed with eclipse mapping techniques to produce spatially resolved spectra of its accretion disc and gas stream as a function of distance from disc centre. The inner accretion disc is characterized by a blue continuum filled with absorption bands and lines which cross over to emission with increasing disc radius, similar to that reported by Rutten et al (1994) at optical wavelengths. The comparison of spatially resolved spectra at different azimuths reveals a significant asymmetry in the disc emission at UV wavelengths, with the disc side closest to the secondary star showing pronounced absorption by an `iron curtain' and a Balmer jump in absorption. These results suggest the existence of an absorbing ring of cold gas whose density and/or vertical scale increase with disc radius. The spectrum of the infalling gas stream is noticeably different from the disc spectrum at the same radius suggesting that gas overflows through the impact point at disc rim and continues along the stream trajectory, producing distinct emission down to 0.1 RL1. The radial temperature profiles of the continuum maps are well described by a steady-state disc model in the inner and intermediate disc regions. There is evidence of an increase in the mass accretion rate from August to November (from Mdot= 10^{-8.3 +/- 0.1} to 10^{-8.1 +/- 0.1} Msun/yr), in accordance with the observed increase in brightness. Since the UX UMa disc seems to be in a high mass accretion, high-viscosity regime in both epochs, this result suggests that the mass transfer rate of UX UMa varies substantially (~ 50 per cent) on time scales of a few months.
description: 22 pages, 12 figures, latex in MNRAS preprint style. Corrected typos. To appear in MNRAS. For related papers and files see ftp://fsc01.fsc.ufsc.br/pub/bap and http://www.fsc.ufsc.br/~astro
Progress at the Intensity frontier on neutrino-nucleus interaction cross sections and muon ionization cooling
Creators: name: Perdigão Dos Santos, Edward Kevin
Publisher: name: Imperial College London
Year: 2014

description: This thesis presents work done in the context of the Neutrino Intensity Frontier. Cross section measurements for charged current coherent pion production by neutrinos and antineutrinos on argon are presented. These measurements are performed using the Argon Neutrino Test (ArgoNeuT) detector exposed to the NuMI beam at Fermilab. The cross sections are measured to be 2.6^{+1.2}_{-1.0}(stat)^{+0.3}_{-0.4}(syst) x 10^{-38} cm² per argon nucleus for neutrinos at a mean energy of 9.6 GeV and 5.5^{+2.6}_{-2.1}(stat)^{+0.6}_{-0.7}(syst) x 10^{-39} cm² per argon nucleus for antineutrinos at a mean energy of 3.6 GeV. This is the first time this interaction has been measured in argon and the first time it has been measured using an automated analysis. In the context of the Muon Ionization Cooling Experiment (MICE), the later chapters of this thesis present work concerning the precise tracking of muons in the MICE detectors which will be fundamental for the demonstration of ionization cooling. The relation between MICE, the Neutrino Factory and nuSTORM is explored in the early chapters of this thesis and the physics potential of neutrino beams from the decay of muons is reviewed.
title: University extension in Scotland c. 1886-1896
Creators: name: Sutherland, Douglas
Publisher: name: University of Glasgow
Year: 2007
Subjects: subject: Education history, higher education, adult education, university extension, Scotland.

description: The aim of this research was to re-examine the history of university extension in Scotland. The extension movement in England made an important contribution to the development of university adult education, but in Scotland a similar scheme survived for less than ten years and had very little impact. Previous historical examinations of extension have suggested that the main reason for its failure was the relatively open nature of Scottish higher education. Because Scotland's universities (three of which were in large cities) were more accessible than those in England there was - according to this argument - little demand for the access to university-level education that extension could provide. However, this research suggests that the level of demand for extension in Scotland has been consistently underestimated. An examination of the early records of extension organisations suggests that there was substantial initial demand for extension courses and the success of two other university education schemes (the LLA and Patrick Geddes' summer schools) supports this interpretation. However, interest in extension declined very rapidly after the first two years and the evidence points to several significant weaknesses in the Scottish organisation of extension which undermined the appeal of the courses. Firstly, the certificates awarded to serious students had no academic value and were only 'university certificates' by association. The universities were passing through a period of fundamental reform and were perhaps reluctant to validate any scheme which might deprive them of students. Secondly, the local associations had great difficulty in arranging course which offered continuity of study - there was a limited supply of competent extension lecturers and the situation was exacerbated by territorial rivalry between the universities. Overall, this research has found that the lack of genuine university commitment to extension was particularly damaging to the movement. In its early years, the universities had an opportunity to pool their limited resources in a national organisation but, in the face of Glasgow's opposition to united action, went their separate ways. A national organisation with a paid full-time secretary was arguably the only way in which the Scottish universities could have achieved the level of organisation of Oxford, Cambridge or London University. They failed to promote extension independently and by 1896 the movement had collapsed.
MicroRNA mediated biological effects in response to bariatric surgery
Creators: name: Wu, Qianxin
Publisher: name: Imperial College London
Year: 2014

description: Bariatric surgery offers sustained dramatic weight loss and remission of diabetes, yet the mechanisms of these health benefits are not clear. In the present study, I profiled circulating and colorectal miRNAome in response to bariatric surgery (Roux-en-Y gastric bypass). Indeed, the response of circulating and colorectal miRNA profiles to RYGB were striking and selective. Fourteen circulating microRNA and thirteen colorectal microRNA exhibited significantly alteration post RYGB. Interestingly, circulating miR-122 decreased dramatically (56 fold) post RYGB surgery. The expression of hepatic miR-122 and its metabolic targets were examined both in in vivo RYGB surgical model and in an in vitro mechanistic model. Manipulation of miRNA-122 cold induce changes of key enzymes involved in energy metabolism, glucose transport, glycolysis, TCA cycle, pentose phosphate shunt, fatty acid oxidation and gluconeogenesis, suggesting an overall increased energy expenditure status after RYGB. Furthermore, potential mechanisms involved in the control of hepatic miR-122 were investigated, with focus on metabolites (glucose, and fatty acids), hormones (glucocorticoid) and transcription factors (PPARs). Finally, by correlating the circulating miRNAome and metabolome data, we were able to generate a comprehensive landscape of the crosstalk between miRNAs and metabolic pathways. Follow-up studies will allow a detailed understanding of miRNAs responsible for regulating specific metabolic pathways, and conversely identifying metabolites capable of regulating the expression and activity of specific miRNAs.
Additional file 1 of Comparative assessment of orthodontic clear aligner versus fixed appliance for anterior retraction: a finite element study
Creators: name: Xia, Qian
name: Wang, Weixu
name: Wang, Chunjuan
name: Feng, Ge
name: Wang, Chao
name: Song, Jinlin
name: Fan, Yubo
Publisher: name: figshare
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Supplementary Material 1: Additional file 1: Supplementary Figure 1. Different views of the Model C4: (A) Occlusal view of Model C4, red arrow represents the applied force loading (150 g) from hook to the 3D printed palatal plate. (B) Palatal view of Model C4. (C) Occlusal view of the 3D printed lingual retraction hook and the 3D printed palatal plate. (D) Sagittal view of Model C4, the distance from the traction point to the occlusion plane is 18.54 mm. Additional file 2: Supplementary file 1. Determination of the center of resistance (CR) and Determination of the height of lingual retraction hook. Additional file 3: Supplementary Figure 2. (A) Displacement tendencies of central incisor, lateral incisor, and canine in sagittal dimension. (B) Crown-root displacement difference of central incisor, lateral incisor, and canine in sagittal dimension
Targeting the DNA damage response network as a therapeutical strategy in ovarian and pancreatic cancers
Creators: name: Henrique De Sousa, Camila
Publisher: name: Imperial College London
Year: 2014

description: High grade serous (HGS) epithelial ovarian cancer (EOC) and pancreatic ductal adenocarcinoma (PDAC) are among the poorest prognosis neoplasms; both are characterised by defects in DNA damage repair mechanisms, high levels of genomic instability, intra-tumoural heterogeneity and resistance, intrinsic or acquired, to conventional chemotherapy. The DNA damaging agents, gemcitabine and platinum are standard treatments for patients with PDAC and EOC, respectively. Here it is demonstrated that time of onset and levels of DNA double strand breaks (DSB), does not correlate with response to these drugs in PDAC and EOC cell lines. Instead, the duration of these lesions/time of repair differs between drug-sensitive and –resistant cell lines. The AKT pathway is central to cell survival and has been implicated in platinum resistance. Here, it is demonstrated that cisplatin and gemcitabine exposure induces an AKT-dependent, pro-survival, DNA damage response in clinically cisplatin-resistant but not -sensitive cells. AKT is phosphorylated specifically on Serine 473 by DNA-dependent protein kinase catalytic subunit (DNA-PKcs), which is involved in the early stages of DSB repair by the non-homologous end-joining (NHEJ) pathway. Inhibition of DNA-PKcs and/or AKT restores platinum sensitivity in a panel of clinically resistant HGS EOC and PDAC cell lines. This study also identifies that restoration of cisplatin sensitivity by DNA-PKcs inhibition is independent of its role in the NHEJ. Unexpectedly, inhibiting DNA-PKcs was shown to decrease both NHEJ and homologous recombination (HR) activities, and whilst studying the DNA-PKcs effect on EOC and PDAC cell lines, a novel regulatory interaction between DNA-PKcs and RAD51, which assists in the repair of DNA DSB via the HR pathway, was also identified. It is suggested here that the method by which DNA-PKcs is controlling RAD51 is via ubiquitin-mediated proteasomal degradation and this appears to be a cancer-specific feature. It was also identified that RAD51 can be ubiquitinated on three different lysine sites and all of these sites are required for the proteasomal-degradation of RAD51 following DNA-PKcs inhibition. Implications of this finding in the clinical setting could be substantial, as here it is shown that targeting DNA-PKcs downregulates both HR and NHEJ pathways, restoring chemotherapy response in EOC and PDAC cell lines.
Non-compact Lattice QED with Two Charges: Phase Diagram and Renormalization Group Flow
Creators: name: Khan, A. Ali
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: The phase diagram of non-compact lattice QED in four dimensions with staggered fermions of charges 1 and $-1/2$ is investigated. The renormalized charges are determined and found to be in agreement with perturbation theory. This is an indication that there is no continuum limit with non-vanishing renormalized gauge coupling, and that the theory has a validity bound for every finite value of the renormalized coupling. The renormalization group flow of the charges is investigated and an estimate for the validity bound as a function of the cut-off is obtained. Generalizing this estimate to all fermions in the Standard Model,it is found that a cut-off at the Planck scale implies that $α_R$ has to be less than $1/80$. Due to spontaneous chiral symmetry breaking, strongly bound fermion-antifermion composite states are generated. Their spectrum is discussed.
description: 35 pages, LATEX, 26 PostScript figures (uuencoded)
Constraining anomalous gluon self-interactions at the LHC: a reappraisal
Creators: name: Hirschi, V.
name: Maltoni, F.
name: Tsinikos, I.
name: Vryonidou, E.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Anomalous self-interactions of non-abelian gauge fields can be described by higher dimensional operators featuring gauge-invariant combinations of the field strengths. In the case of QCD, the gluon self-interactions start to be modified at dimension six by operators of the type $GGG$, with $G$ the gluon field strength tensor, possibly leading to deviations in all observables and measurements that probe strong interactions at very small distances. In this work we consider the sensitivity to the triple gluon operator of a series of observables at the LHC in di-jet, three- and multi-jet final states and heavy-quark production. We critically re-examine the robustness of long-standing as well as more recent proposals addressing issues such as the validity of the EFT expansion and the impact of higher order QCD corrections. Our results support the conclusion that multi-jet observables can reliably bound these anomalous interactions to the level that their impact on other key observables at the LHC, involving for example top quark and Higgs production, can be safely neglected. We also highlight the potential of using previously suggested angular observables in three-jet events at the LHC to further constrain these interactions.
description: published version, reference added
Green and efficient determination of ʟ-dopa in complex polypill formulations using a magnetic microplate
Creators: name: Hweiyan Tsai
name: Chia-Yi Chen
name: Yi-Hsuan Lu
name: Lai, Ya-Yun
name: Chwan-Bor Fuh
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer

description: A high-throughput and selective method for the determination of ʟ-dopa (levodopa) in complex formulations was developed. The method is based on the oxidation of ʟ-dopa to yield dopachrome using tyrosinase-labeled magnetic nanoparticles (TYR-MNPs) as the oxidation catalyst. TYR-MNP activity was retained at 75% after 20 reuse cycles, which is superior to previously reported systems that employ other substrates or cross-linkers for the immobilization of tyrosinase. In addition, the precision (< 3%), accuracy (recovery = 95–102%), and selectivity of the newly developed quantitative-analysis method for ʟ-dopa in complex polypill formulations meets the pharmaceutical industry’s quality-control requirements; consequently this method can be applied to the routine analysis of complex formulations. The quality-control assay uses 96-well microplates, which reduces the required volume of reagents, and the tyrosinase can easily be recycled and reused using an in-house-prepared magnetic microplate, thereby rendering the proposed method economical and less wasteful than existing methods.
Environmental risk analysis and management associated with Carbon Capture and Storage (CCS)
Creators: name: Oraee-Mirzamani, Behdeen
Publisher: name: Imperial College London
Year: 2014

description: CCS legislation is currently comprised of an overlapping network of international agreements and regional policies which form a strong basis for environmental protection for potential leakage of CO2 from underground storage sites. However, these legislative instruments form an uncoordinated legal basis for CCS with overly stringent liability provisions posing a significant barrier to stakeholder investment, technology development and future roll-out of commercial scale CCS projects. A number of insurance companies have recently developed different types of insurance mechanisms for covering CO2 storage facilities. Whilst these types of insurance policies are beneficial in encouraging the CCS industry in general, there are also drawbacks. Mostly, they only cover the CO2 capture facility during the operational phase of power plants or they solely cover the facility for 10 to 30 years after injection has been completed and storage sites have been sealed off. Furthermore, there is no standard regime for a comprehensive insurance mechanism for commercial scale CO2 storage facilities due to lack of enough information in regards to the long-term liability of potential CO2 leakage, type of risks involved in the technology of geological storage of CO2 and the likelihood of occurrence of these perceived. This research has identified the main risks associated with CO2 storage under geological formations and has developed a novel mechanism that enables the insurance industry to assess the risks of CO2 storage more effectively and therefore adjust their premium rates more in favour of CCS projects. In addition, this will also be beneficial for regulators in enabling them to regulate more effectively in order to incentivise stakeholder participation and investment in the CCS technology. The said mechanism has been developed using a range of systems engineering optimization techniques in order to assess the significance and criticality of the risks of CO2 leakage through the caprock and their likelihood of occurrence.
Deconfinement transition and dimensional cross-over in the 3D gauge Ising model
Creators: name: Caselle, M.
name: Hasenbusch, M.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We present a high precision Monte Carlo study of the finite temperature $Z_2$ gauge theory in 2+1 dimensions. The duality with the 3D Ising spin model allows us to use powerful cluster algorithms for the simulations. For temporal extensions up to $N_t=16$ we obtain the inverse critical temperature with a statistical accuracy comparable with the most accurate results for the bulk phase transition of the 3D Ising model. We discuss the predictions of T. W. Capehart and M.E. Fisher for the dimensional crossover from 2 to 3 dimensions. Our precise data for the critical exponents and critical amplitudes confirm the Svetitsky-Yaffe conjecture. We find deviations from Olesen's prediction for the critical temperature of about 20%.
description: latex file of 21 pages plus 1 ps figure. Minor corrections in the figure. Text unchanged
Additional file 1 of Comparative genomics and physiological investigation supported safety, cold adaptation, efficient hydrolytic and plant growth-promoting potential of psychrotrophic Glutamicibacter arilaitensis LJH19, isolated from night-soil compost
Creators: name: Borker, Shruti Sinai
name: Thakur, Aman
name: Kumar, Sanjeet
name: Kumari, Sareeka
name: Kumar, Rakshak
name: Kumar, Sanjay
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1.
Precession Motion in Levitated Optomechanics
Creators: name: Rashid, Muddassar
name: Toroš, Marko
name: Setter, Ashley
name: Ulbricht, Hendrik
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Applied Physics (physics.app-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We investigate experimentally the dynamics of a non-spherical levitated nanoparticle in vacuum. In addition to translation and rotation motion, we observe the light torque-induced precession and nutation of the trapped particle. We provide a theoretical model, which we numerically simulate and from which we derive approximate expressions for the motional frequencies. Both, the simulation and approximate expressions, we find in good agreement with experiments. We measure a torque of $1.9 \pm 0.5 \times 10^{-23}$ Nm at $1 \times 10^{-1}$ mbar, with an estimated torque sensitivity of $3.6 \pm 1.1 \times 10^{-31}$ Nm/$\sqrt{\text{Hz}}$ at $1 \times 10^{-7}$ mbar.
description: 10 pages, 4 figures
Instantons and Monopoles in the Maximally Abelian Gauge
Creators: name: Hart, A.
name: Teper, M.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We study the Abelian projection of SU(2) instantons in the Maximally Abelian gauge. We find that in this gauge an isolated instanton produces a closed monopole loop within its core and the size of this loop increases with the core size. We show that this result is robust against the introduction of small quantum fluctuations. We investigate the effects of neighbouring (anti)instantons upon each other and show how overlapping (anti)instantons can generate larger monopole loops. We find, however, that in fields that are typical of the fully quantised vacuum only some of the large monopole loops that are important for confinement have a topological origin. We comment on what this may imply for the role of instantons in confinement and chiral symmetry breaking.
description: 14 pages LaTeX plus 5 PostScript figures. Uses epsf.sty. Self-unpacking, uuencoded tar-compressed file
BERILGANLAR BAZASI USTIDA ISHLASH. YANGI BERILGANLARNI JADVALGA QO'SHISH. BERILGANLARNI O'ZGARTIRISH.
Creators: name: Sharofutdinov, Iqboljon
name: Xomidova, Mohichexra
Publisher: name: Zenodo
Year: 2024

description: Maqolada SQL (Structured Query Language) — ma'lumotlar bazalarini boshqarish uchun ishlatiladigan standart dasturlash tili haqida batafsil ma'lumot berilgan. SQL ma'lumotlar bazasidagi ma'lumotlarni qo'shish, yangilash, o'chirish va so'rash kabi asosiy amaliyotlarni bajarish imkonini beradi. Ushbu maqola SQLning asosiy operatirlari va uning ma'lumotlar bazasini boshqarishdagi muhim roli haqida to'liq tushuncha beradi. Shuningdek, maqolada SQLning xavfsizlik, tranzaksiya boshqaruvi, ma'lumotlar bazasi ob'ektlarini yaratish va boshqarish kabi xususiyatlariga ham to'xtalib o'tilgan. Maqola, shuningdek, SQLning ma'lumotlar bazasi bilan ishlash jarayonlarida qanday qilib samaradorlik va ishonchlilikni ta'minlashga yordam berishi mumkinligini ko'rsatib beradi. Bu maqola, ma'lumotlar bazasi bilan ishlovchi mutaxassislar va dasturchilar uchun foydali bo'lib, ularning SQL bilan ishlash ko'nikmalarini oshirishga yordam beradi.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 1307
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: Petot, Frédéric
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1307, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1307, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Keck Spectra of Pleiades Brown Dwarf Candidates and a Precise Determination of the Lithium Depletion Edge in the Pleiades
Creators: name: Stauffer, John
name: Schultz, Greg
name: Kirkpatrick, J. Davy
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have obtained intermediate resolution spectra of eleven candidate brown dwarf members of the Pleiades open cluster using the Keck II telescope and LRIS spectrograph. Our primary goal was to determine the location of the "lithium depletion edge" in the Pleiades and hence to derive a precise age for the cluster. All but one of our 11 program objects have radial velocities appropriate for Pleiades members, have moderately strong H alpha emission, and have spectral types M6 to M8.5, as expected for their (R-I) colors. We have constructed a color-magnitude diagram for the faint end of the Pleiades main sequence, including only stars for which high S/N spectra in the region of the lithium 6708 Angstrom absorption line have been obtained. These data allow us to accurately determine the Pleiades single-star lithium depletion edge at I(c0) = 17.80, R-I(c0) = 2.20, spectral type = M6.5. By reference to theoretical evolutionary models, this converts fairly directly into an age for the Pleiades of 125 Myr. This is significantly older than the age that is normally quoted, but does agree with some other recent estimates.
description: 12 pages, including 3 Figures. Accepted by ApJ Letters
Lattice Investigations of the Running Coupling
Creators: name: Weisz, Peter
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: A review of investigations of running couplings using lattice techniques is given. This includes i) studies of the running of particular non-perturbatively defined renormalized couplings in pure gauge theories over a range of energies, and ii) how estimates of $α_{\overline{MS}}(m_Z)$ in lattice QCD are presently obtained.
description: uuencoded postscript file
Below the Lyman Edge: UV Polarimetry of Quasars
Creators: name: Koratkar, Anuradha
name: Antonucci, Robert
name: Goodrich, Robert
name: Storrs, Alex
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The Lyman edge at 912 Åis an important diagnostic region for studying quasi-stellar objects (QSOs). In particular, it reveals a great deal about the physical conditions within the atmospheres of accretion disks, a ubiquitous component of QSO theories. A robust prediction of accretion disk models is a significant polarization due to electron scattering just longward (in wavelength) of the Lyman edge because of the wavelength dependence of the Hydrogen absorption opacity. Observations of the Lyman edge regions of QSOs have shown scant evidence for the predicted features-few QSOs show the broad, partial Lyman edges expected to be common according to most theories, and none show the high polarizations expected longward of the Lyman edge. Still, polarization spectra of a small number of QSOs have shown a rising polarization (up to 20%) at wavelengths shortward of the Lyman edge. We have now doubled our sample of intermediate-redshift QSOs observed with the HST/FOS spectropolarimeter to determine the amount of polarization on both sides of the Lyman limit. For this new sample of six objects, polarizations are low and mostly consistent with zero below the Lyman edge. Another important result of the new data is that it strengthens the conclusion that quasars are generally not polarized significantly just longward of the Lyman edge at $\sim 1000 Å. There is no significant statistical wavelength dependence to the polarization longward of the Lyman edge indicating that simple plane-parallel atmospheres with scattering-dominated opacity are not significant sources of UV flux in quasars.
description: Accepted to Ap.J., 30 pages, 8 figures
Testing the Quasi-temporal Gauge on the Lattice
Creators: name: Conti, Livio
name: Parrinello, Claudio
name: Petrarca, Silvano
name: Vladikas, Anastassios
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We investigate the viability of the quasi-temporal gauge on the lattice. This is a complete gauge fixing condition that can be implemented on the lattice at a very low computational cost. As a test case, using the Clover action, we have evaluated the (gauge invariant) renormalisation constant of the non-singlet axial current, using Ward identities extracted from quark states. Our result is in reasonable but not complete agreement with previous values obtained from Ward identities both on hadronic states and on quark states in the Landau gauge. We observe large fluctuations due to lattice Gribov copies. The influence of finite volume effects is expected to be non-negligible in the case we are considering.
description: 10 pages, uuencoded Postscript file including 2 figures
MOESM1 of An effective snakebite first aid training method for medics in the Chinese troops: a RCT
Creators: name: Qiu, Chen
name: Qiu, Xiao-Feng
name: Liu, Jing-Jing
name: Wang, Yi-Xin
name: Gui, Li
Publisher: name: figshare
Year: 2019
Subjects: Biochemistry
Medicine
Science Policy

description: Additional file 1. Part 1. Scoring table for snakebite first aid. Part 2. Snakebite scenarios. Part 3. A socio-demographic information questionnaire. Part 4. Acceptance questionnaire of the SOP and checklist.
Additional file 1 of Association between brain amyloid deposition and longitudinal changes of white matter hyperintensities
Creators: name: Cha, Woo-Jin
name: Yi, Dahyun
name: Ahn, Hyejin
name: Byun, Min Soo
name: Chang, Yoon Young
name: Choi, Jung-Min
name: Kim, Kyungtae
name: Choi, Hyeji
name: Jung, Gijung
name: Kang, Koung Mi
name: Sohn, Chul-Ho
name: Lee, Yun-Sang
name: Kim, Yu Kyeong
name: Lee, Dong Young
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Mental Health

description: Supplementary Material 1
Critical Slowing-Down in $SU(2)$ Landau Gauge-Fixing Algorithms
Creators: name: Cucchieri, Attilio
name: Mendes, Tereza
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We study the problem of critical slowing-down for gauge-fixing algorithms (Landau gauge) in $SU(2)$ lattice gauge theory on a $2$-dimensional lattice. We consider five such algorithms, and lattice sizes ranging from $8^{2}$ to $36^{2}$ (up to $64^2$ in the case of Fourier acceleration). We measure four different observables and we find that for each given algorithm they all have the same relaxation time within error bars. We obtain that: the so-called {\em Los Alamos} method has dynamic critical exponent $z \approx 2$, the {\em overrelaxation} method and the {\em stochastic overrelaxation} method have $z \approx 1$, the so-called {\em Cornell} method has $z$ slightly smaller than $1$ and the {\em Fourier acceleration} method completely eliminates critical slowing-down. A detailed discussion and analysis of the tuning of these algorithms is also presented.
description: 40 pages (including 10 figures). A few modifications, incorporating referee's suggestions, without the length reduction required for publication
CURRENT STATE OF STANDARDIZATION IN THE FIELD OF METROLOGICAL SUPPORT OF INFORMATION AND MEASUREMENT SYSTEMS
Creators: name: Khatmullina, R.
name: Shutkova D.
name: Vaks, M.
Publisher: name: Norwegian Journal of Development of the International Science
Year: 2021
Subjects: metrological support
information and measurement systems
measurement channels

description: The article considers the requirements of existing national and foreign standards in the field of metrological support of information and measurement systems. The results of a comparative analysis of GOST R 8.596-2002 and the first edition of its draft are reflected.
Spiral galaxies with WFPC2: II. The Nuclear Properties of 40 objects
Creators: name: Carollo, C. M.
name: Stiavelli, M.
name: Mack, J.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the analysis of HST WFPC2 F606W images of 40 spirals belonging to the sample introduced in Carollo et al. (paper I), where 35 other targets were discussed. We describe the optical morphology of the new 40 galaxies, derive the surface brightness profiles for 25 of them, and present the results of photometric decompositions of these profiles into a ``bulge'' (R^1/4 or exponential) and a disk component. The analysis of the sample of 75 galaxies puts on a statistically more solid ground the main results presented in paper I. Furthermore, the analysis of the sample of 75 objects shows that: A. Several of the non-classical inner structures are well fitted by an exponential profile. These ``exponential bulges'' are fainter than R^1/4 bulges for given total galaxy luminosity and (catalog) Hubble type later than Sab. B. Irregular/exponential bulges typically host central compact sources. C. The central sources are present in all types of disk galaxies, starting with systems as early as S0a. About 60 % of Sb to Sc galaxies host a central compact source. Many of the galaxies which host compact sources contain a barred structure. D. Galaxies with apparent nuclear star formation and the brightest compact sources, are preferentially the early- and intermediate- type (S0a-Sb) systems. E. None of the features depends on environment: isolated and not isolated galaxies show indistinguishable properties. Independently from the physical nature of the non-classical inner structures, our main conclusion is that a significant fraction of galaxies classified from the ground as relatively early-type shows a rich variety of central properties, and little or no morphological/photometric evidence for a smooth, R^1/4-law bulge.
description: 30 pages, 6 figures - AJ in press
Slow Normal Modes of Proteins are Accurately Reproduced across Different Platforms
Creators: name: Na, Hyuntae
name: ben-Avraham, Daniel
name: Tirion, Monique M.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Biomolecules (q-bio.BM)
subject: FOS: Biological sciences

description: The Protein Data Bank (PDB) contains the atomic structures of over 105 biomolecules with better than 2.8A resolution. The listing of the identities and coordinates of the atoms comprising each macromolecule permits an analysis of the slow-time vibrational response of these large systems to minor perturbations. 3D video animations of individual modes of oscillation demonstrate how regions interdigitate to create cohesive collective motions, providing a comprehensive framework for and familiarity with the overall 3D architecture. Furthermore, the isolation and representation of the softest, slowest deformation coordinates provide opportunities for the development of me- chanical models of enzyme function. The eigenvector decomposition, therefore, must be accurate, reliable as well as rapid to be generally reported upon. We obtain the eigenmodes of a 1.2A 34kDa PDB entry using either exclusively heavy atoms or partly or fully reduced atomic sets; Cartesian or internal coordinates; interatomic force fields derived either from a full Cartesian potential, a reduced atomic potential or a Gaussian distance-dependent potential; and independently devel- oped software. These varied technologies are similar in that each maintains proper stereochemistry either by use of dihedral degrees of freedom which freezes bond lengths and bond angles, or by use of a full atomic potential that includes realistic bond length and angle restraints. We find that the shapes of the slowest eigenvectors are nearly identical, not merely similar.
description: 20 pages plus 7 figures/tables (version to conform with referees remarks)
Phenolic composition, antioxidant capacity and inhibitory effects on α-glucosidase and lipase of immature faba bean seeds
Creators: name: Lu, Yue-Hong
name: Cheng-Rui Tian
name: Gao, Chun-Yan
name: Bi-Ni Wang
name: Yang, Wen-Yi
name: Kong, Xiao
name: Chai, Li-Qin
name: Guo-Chen Chen
name: Yin, Xue-Fen
name: He, Yu-Hua
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Immature faba bean seeds of five varieties were investigated for changes in phenolic composition, antioxidant capacity and inhibitory effects on α-glucosidase and lipase at three edible stages (S1, S2 and S3). Phenolics and antioxidant capacity in seed coats were significantly higher than those in cotyledons, and the highest was found of FD18 at stage S3. While phenolic content in cotyledons decreased steadily with the harvest time delayed. Eight phenolic compounds were confirmed with epicatechin and catechin prominent and their levels showed a great variability depending on varieties, maturation stages and plant parts of faba bean seeds. Unexpectedly, the inhibitory effects of purified phenolics on α-glucosidase were even stronger than that of the positive control acarbose, and the inhibitory effects on lipase in the cotyledons declined gradually from stage S1 to S3. Significant positive correlations between phenolics from seed coats and antioxidant capacity, and phenolics from cotyledons and the enzyme inhibitory effects were observed. Overall, the immature faba bean seed, especially its seed coat, has great potential as a functional food.
Analysis of risk mitigation measures in agricultural trade
Creators: name: Pearson, Lee Michael
Publisher: name: Imperial College London
Year: 2014

description: International trade has brought tremendous choice to consumers and expanded markets for producers. Cross-border exchange also brings import risks such as food contaminants and invasive species. Balancing legitimate concerns to protect health and the environment with avoiding protectionist use of risk-based measures is highly important to the integrity of the multilateral trading system. This research studies three aspects of the relation between domestic regulations and international trade. Firstly, this thesis provides evidence addressing an ongoing international policy debate. This thesis is the first to show that the 8,487 new risk-based regulations under the Sanitary Phytosanitary (SPS) Agreement and 4,745 regulations under Technical Barriers to Trade (TBT) Agreement notified from 1996-2010 are driven in part by loss of tariff protection and country-level environmental governance factors. Declining tariffs, however, do not make the implementation of “suspect” SPS (i.e. measures later subject to a trade concern) more likely. This suggests policymakers may be systematically choosing to work on products that have lost tariff protection, but not systemically putting in illegitimate, non-tariff barriers to compensate. Secondly, this thesis investigates the patterns of Specific Trade Concerns (STCs) raised against 292 suspect SPS policies and 282 suspect TBT policies by members of the WTO from 1996-2010. It was found that developing countries struggle to resolve concerns they raise against developed economies. From work on 79 plant health concerns, it was clear that countries raise STCs using science-based and economics-based arguments of illegitimacy. Lastly, SPS measures are implemented to reduce risks transmitted via trade, but the effectiveness of risk reduction depends as well on actions of supply chain actors before export. A case study on coffee pests and diseases from a survey of 119 growers and 89 traders in Uganda is presented to scrutinize the decision-making process of growers in a high pest/disease prevalence environment.