cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ASSESSING THE APPLICABILITY AND ACCURACY OF MOLECULAR DOCKING TO STUDY THE INTERACTIONS OF LIGANDS WITH GPCRS
Creators: name: Dolatmoradi, Marjan
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences

description: G protein-coupled receptors (GPCRs) constitute the largest superfamily of cell membrane proteins that are involved in various physiological processes, and are the target of the majority of marketed drugs. A deeper insight into the structural interaction between GPCRs and ligands can be gained with computational studies. Molecular docking and virtual screening have become valuable tools for in silico prediction of ligand-receptor interaction, and investigate the binding affinities of candidate molecules to a given target. In this work, the accuracy of molecular docking at reproducing the crystallographic structures of 25 ligands in complex with GPCR structures was determined using standard precision (SP) and extra precision (XP) scoring functions. In addition, the correlation between the results obtained from the cognate ligand redocking and virtual screening, and the applicability of implemented strategy to study GPCRs were investigated.
Fast Implementation of Morphological Filtering Using ARM NEON Extension
Creators: name: Limonova, Elena
name: Terekhin, Arseny
name: Nikolaev, Dmitry
name: Arlazarov, Vladimir
Publisher: name: arXiv
Year: 2020
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Image and Video Processing (eess.IV)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 68T45

description: In this paper we consider speedup potential of morphological image filtering on ARM processors. Morphological operations are widely used in image analysis and recognition and their speedup in some cases can significantly reduce overall execution time of recognition. More specifically, we propose fast implementation of erosion and dilation using ARM SIMD extension NEON. These operations with the rectangular structuring element are separable. They were implemented using the advantages of separability as sequential horizontal and vertical passes. Each pass was implemented using van Herk/Gil-Werman algorithm for large windows and low-constant linear complexity algorithm for small windows. Final implementation was improved with SIMD and used a combination of these methods. We also considered fast transpose implementation of 8x8 and 16x16 matrices using ARM NEON to get additional computational gain for morphological operations. Experiments showed 3 times efficiency increase for final implementation of erosion and dilation compared to van Herk/Gil-Werman algorithm without SIMD, 5.7 times speedup for 8x8 matrix transpose and 12 times speedup for 16x16 matrix transpose compared to transpose without SIMD.
description: 6 pages, 4 figures
The Effects of Smoking Availability and Environmental Smoking Cues on Smoking Motivation
Creators: name: Stahl, Naomi
Publisher: name: American University
Year: 2023

description: Conditioned reactions (e.g., cravings) to drug-related stimuli (e.g., objects, emotions, or situations associated with drug taking) have been examined as a potential mechanism to explain the maintenance of drug use and relapse. There is evidence that the expectation that a drug is available for consumption can enhance reactivity to environmental drug stimuli as well as possibly serve as a conditioned stimulus in its own right. Prior studies have found that smokers report greater urges to smoke when they expect to smoke sooner (e.g., 20 minutes) than later (e.g., 3 hours), with greater reactions when smoking stimuli (e.g., pack of cigarettes) are present. However, reactions to extended delays before smoking is available have not been adequately investigated (e.g., delays greater than 4 hours). Using a between-subjects factorial design, daily smokers (N=180; 112 male, 68 female) were randomized into one of six conditions in which instructions about the next available opportunity to smoke (20 minutes, 3 hours, or 24 hours) were cross with exposure to stimuli (smoking-related or neutral cues). Smoking urge, withdrawal, mood, and reaction time were assessed before and after the manipulation. Then all participants were told that they would have an opportunity to smoke and took part in a smoking versus money choice procedure for 50 minutes. Analyses revealed a main effect of availability on withdrawal symptoms, F(2,173) = 5.414, p < .001 and negative mood, F(2,173) = 8.725, p < .001, which were highly correlated (r = .87). Post-hoc comparisons revealed that those told 24 hours had significantly greater withdrawal symptoms and negative mood compared to those told 20 min and 3 hrs. No main effects of availability were found for urge, positive mood, or reaction time. There were also no main effects for smoking stimuli and no availability by smoking stimuli interactions. Participants who were initially exposed to neutral stimuli and then exposed to smoking stimuli during the choice procedure were more likely to smoke than those already exposed to smoking stimuli. A better understanding of the influence of cognitive and environmental stimuli on smoking motivation and behavior may inform the development of innovative cognitive behavioral treatment strategies for smoking cessation.
An intergenerational androgenic mechanism of female intrasexual competition in the cooperatively breeding meerkat.
Creators: name: Drea, Christine M
name: Davies, Charli S
name: Greene, Lydia K
name: Mitchell, Jessica
name: Blondel, Dimitri V
name: Shearer, Caroline L
name: Feldblum, Joseph T
name: Dimac-Stohl, Kristin A
name: Smyth-Kabay, Kendra N
name: Clutton-Brock, Timothy
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Article
/631/158/856
/631/443/494
/13
article

description: Female intrasexual competition can be intense in cooperatively breeding species, with some dominant breeders (matriarchs) limiting reproduction in subordinates via aggression, eviction or infanticide. In males, such tendencies bidirectionally link to testosterone, but in females, there has been little systematic investigation of androgen-mediated behaviour within and across generations. In 22 clans of wild meerkats (Suricata suricatta), we show that matriarchs 1) express peak androgen concentrations during late gestation, 2) when displaying peak feeding competition, dominance behaviour, and evictions, and 3) relative to subordinates, produce offspring that are more aggressive in early development. Late-gestation antiandrogen treatment of matriarchs 4) specifically reduces dominance behaviour, is associated with infrequent evictions, decreases social centrality within the clan, 5) increases aggression in cohabiting subordinate dams, and 6) reduces offspring aggression. These effects implicate androgen-mediated aggression in the operation of female sexual selection, and intergenerational transmission of masculinised phenotypes in the evolution of meerkat cooperative breeding.
Revisiting the $Ω(2012)$ as a hadronic molecule and its strong decays
Creators: name: Lu, Jun-Xu
name: Zeng, Chun-Hua
name: Wang, En
name: Xie, Ju-Jun
name: Geng, Li-Sheng
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Recently, the Belle collaboration measured the ratios of the branching fractions of the newly observed $Ω(2012)$ excited state. They did not observe significant signals for the $Ω(2012) \to \bar{K} Ξ^*(1530) \to \bar{K} πΞ$ decay, and reported an upper limit for the ratio of the three body decay to the two body decay mode of $Ω(2012) \to \bar{K} Ξ$. In this work, we revisit the newly observed $Ω(2012)$ from the molecular perspective where this resonance appears to be a dynamically generated state with spin-parity $3/2^-$ from the coupled channels interactions of the $\bar{K} Ξ^*(1530)$ and $ηΩ$ in $s$-wave and $\bar{K} Ξ$ in $d$-wave. With the model parameters for the $d$-wave interaction, we show that the ratio of these decay fractions reported recently by the Belle collaboration can be easily accommodated.
description: Published version. Published in Eur.\ Phys.\ J.\ C {\bf 80}, 361 (2020)
Austrothaumalea denticulata Theischinger 1986
Creators: name: Sinclair, Bradley J.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Thaumaleidae
Austrothaumalea
Austrothaumalea denticulata

description: Austrothaumalea denticulata Theischinger
 Austrothaumalea denticulata Theischinger, 1986: 301.
 Material examined. New South Wales: 4 ??, Blue Mtns NP, Blackheath, Grose Gorge, Govetts Ck, 1,25. xii.1993 (CNC); 3 ??, 7 !!, Blue Mtns NP, Grand Canyon, rainfor. stream, 25.xii.1993 (AMS); 8 ??, Blue Mtns NP, Mt. Wilson, Waterfall Ck, 13.xii.1998 (ANIC); 1 ?, Blue Mtns NP, Popes Glen, 31.x.1994 (AMS); 2 ??, Blue Mtns NP, Valley of the Waters below Vera Falls, 320 m, 9.iv.1995 (ANIC); 7 ??, 8 !! (incl. 2 ?? reared from pupae), Sydney, Edgecliff, Trumper Pk, cliff seepage, 14.xi.1993 (CNC); 8 ??, 6 !!, same locality, 9.xi.1994 (AMS); 18 ??, 5 !!, Sydney, Kirribilli, roadcut seep, 5.xi.1993 (AMS, ANIC); 1 ?, 1 !, Sydney, Mosman, Ashton Pk, stream, 31.x.1993 (AMS); 1 ?, Wentworth Falls, Jamison Ck /seeps, 10.xi.1993 (ANIC); 8 ??, 1 !, Wentworth Falls, Valley of the Waters, cascading ck, 3.i., 23.x.1994, 9.iv.1995 (AMS). Queensland: 1 ?, Bunya Mtns NP, Paradise Falls, 8.x.2002 (ZFMK). Victoria: 4 ??,1 !, Mt. Buffalo NP, Eurobin Ck, 400 m, 30.xi.1994 (CNC); 1 ?, Errinundra Plateau, Gap Rd, Result Ck Falls, 6–7.xii.1994 (AMS).
 Distribution. The species ranges from Tasmania to south of Townsville, Queensland.
 Remarks. The larva and pupa of this species were described by Sinclair (2000). The gonocoxal plate bears a crown of minute denticles along the ventral margin, directed anteriorly. These denticles are not shown in Theischinger (1986, fig. 31).
description: Published as part of Sinclair, Bradley J., 2008, New Species of Austrothaumalea Tonnoir from Australia (Diptera: Thaumaleidae), pp. 1-12 in Records of the Australian Museum 60 (1) on page 7, DOI: 10.3853/j.0067-1975.60.2008.1490, http://zenodo.org/record/4676495
A Qualitative Study of the Social Relationship Experiences Across the Life Course Among Black/African American Women Aging With HIV in the South
Creators: name: Cary, Michael
name: Moore, Elizabeth D.
name: Caiola, Courtney
name: Humphreys, Janice
Publisher: name: Wolters Kluwer
Year: 2024

description:
Black/African American women continue to be disproportionately affected by HIV, facing multiple intersecting challenges that influence how they age and effectively manage their health. Supportive social relationships have been shown to help mitigate challenges and improve health in women with HIV, but little is known about Black/African American women's perceptions of social relationships. Guided by Life Course Theory, in-depth life history interviews were conducted with 18 Black/African American women aged 50+ years. In older adulthood, most important relationships among Black/African American women were with their adult children and grandchildren, intimate partners, God, and friends from the community. Factors that influenced relationships over time included: (a) a desire to build a community; (b) a need to empower oneself and give back; (c) yearning to engage the younger generation; and (d) battling HIV stigma. Older Black/African American women with HIV played a critical role in the education of the younger generation.
The Effects of Smoking Availability and Environmental Smoking Cues on Smoking Motivation
Creators: name: Stahl, Naomi
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 52
subject: Psychology
subject: FOS: Psychology
classificationCode: 5203
subject: Clinical and health psychology

description: Conditioned reactions (e.g., cravings) to drug-related stimuli (e.g., objects, emotions, or situations associated with drug taking) have been examined as a potential mechanism to explain the maintenance of drug use and relapse. There is evidence that the expectation that a drug is available for consumption can enhance reactivity to environmental drug stimuli as well as possibly serve as a conditioned stimulus in its own right. Prior studies have found that smokers report greater urges to smoke when they expect to smoke sooner (e.g., 20 minutes) than later (e.g., 3 hours), with greater reactions when smoking stimuli (e.g., pack of cigarettes) are present. However, reactions to extended delays before smoking is available have not been adequately investigated (e.g., delays greater than 4 hours). Using a between-subjects factorial design, daily smokers (N=180; 112 male, 68 female) were randomized into one of six conditions in which instructions about the next available opportunity to smoke (20 minutes, 3 hours, or 24 hours) were cross with exposure to stimuli (smoking-related or neutral cues). Smoking urge, withdrawal, mood, and reaction time were assessed before and after the manipulation. Then all participants were told that they would have an opportunity to smoke and took part in a smoking versus money choice procedure for 50 minutes. Analyses revealed a main effect of availability on withdrawal symptoms, F(2,173) = 5.414, p < .001 and negative mood, F(2,173) = 8.725, p < .001, which were highly correlated (r = .87). Post-hoc comparisons revealed that those told 24 hours had significantly greater withdrawal symptoms and negative mood compared to those told 20 min and 3 hrs. No main effects of availability were found for urge, positive mood, or reaction time. There were also no main effects for smoking stimuli and no availability by smoking stimuli interactions. Participants who were initially exposed to neutral stimuli and then exposed to smoking stimuli during the choice procedure were more likely to smoke than those already exposed to smoking stimuli. A better understanding of the influence of cognitive and environmental stimuli on smoking motivation and behavior may inform the development of innovative cognitive behavioral treatment strategies for smoking cessation.
Charge transport through a SET with a mechanically oscillating island
Creators: name: Chtchelkatchev, N. M.
name: Belzig, W.
name: Bruder, C.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We consider a single-electron transistor (SET) whose central island is a nanomechanical oscillator. The gate capacitance of the SET depends on the mechanical displacement, thus, the vibrations of the island vibrations may strongly influence the current-voltage characteristics, current noise, and higher cumulants of the current. Harmonic oscillations of the island and oscillations with random amplitude (e.g., due to the thermal activation) change the transport characteristics in a different way. The noise spectrum has a peak at the frequency of the island oscillations; when the island oscillates harmonically, the peak reduces to a $δ$-peak. We show that knowledge of the SET transport properties helps to determine in what way the island oscillates, to estimate the amplitude, and the frequency of the oscillations.
Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer's Disease.
Creators: name: Runfola, Massimiliano
name: Perni, Michele
name: Yang, Xiaoting
name: Marchese, Maria
name: Bacci, Andrea
name: Mero, Serena
name: Santorelli, Filippo M
name: Polini, Beatrice
name: Chiellini, Grazia
name: Giuliani, Daniela
name: Vilella, Antonietta
name: Bodria, Martina
name: Daini, Eleonora
name: Vandini, Eleonora
name: Rudge, Simon
name: Gul, Sheraz
name: Wakelam, Michale OJ
name: Vendruscolo, Michele
name: Rapposelli, Simona
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Alzheimer’s disease
polypharmacology
C. elegans
autophagy
drug discovery
zebrafish
5XFAD mice

description: The identification of effective pharmacological tools for Alzheimer's disease (AD) represents one of the main challenges for therapeutic discovery. Due to the variety of pathological processes associated with AD, a promising route for pharmacological intervention involves the development of new chemical entities that can restore cellular homeostasis. To investigate this strategy, we designed and synthetized SG2, a compound related to the thyroid hormone thyroxine, that shares a pleiotropic activity with its endogenous parent compound, including autophagic flux promotion, neuroprotection, and metabolic reprogramming. We demonstrate herein that SG2 acts in a pleiotropic manner to induce recovery in a C. elegans model of AD based on the overexpression of Aβ42 and improves learning abilities in the 5XFAD mouse model of AD. Further, in vitro ADME-Tox profiling and toxicological studies in zebrafish confirmed the low toxicity of this compound, which represents a chemical starting point for AD drug development.
title: Ciągłość przestrzenna jako kluczowy element funkcjonowania systemu zieleni miasta
Creators: name: Michalak, Hanna
Publisher: name: Publishing House of Poznan University of Technology
Year: 2020

description: Zeszyty Naukowe Politechniki Poznańskiej. Architektura, Urbanistyka, Architektura wnętrz, 1, 119-150
Hydrogen Peroxide Formation Rates in a PEMFC Anode and Cathode: Effect of Humidity and Temperature
Creators: name: Sethuraman, Vijay A.
name: Weidner, John W.
name: Haug, Andrew T.
name: Motupally, Sathya
name: Protsailo, Lesia V.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Applied Physics (physics.app-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Hydrogen peroxide (H2O2) formation rates in a proton exchange membrane (PEM) fuel cell anode and cathode were estimated as a function of humidity and temperature by studying the oxygen reduction reaction (ORR) on a rotating ring disc electrode (RRDE). Fuel cell conditions were replicated by depositing a film of Pt/Vulcan XC-72 catalyst onto the disk and by varying the temperature, dissolved O2 concentration and the acidity levels in hydrochloric acid (HClO4). The HClO4 acidity was correlated to ionomer water activity and hence fuel cell humidity. The H2O2 formation rates showed a linear dependence on oxygen concentration and square dependence on water activity. The H2O2 selectivity in ORR was independent of oxygen concentration but increased with decrease in water activity (i.e., decreased humidity). Potential dependent activation energy for the H2O2 formation reaction was estimated from data obtained at different temperatures.
description: 29 pages, 10 figures. arXiv admin note: substantial text overlap with arXiv:1308.4042
Additional file 7 of Exercising with Baxter: preliminary support for assistive social-physical human-robot interaction
Creators: name: Fitter, Naomi T.
name: Mohan, Mayumi
name: Kuchenbecker, Katherine J.
name: Johnson, Michelle J.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 7 Gameplay flow of the Agility Game.
Repulsive Interactions in the Microstructure of Regular Hayward Black Hole in Anti-de Sitter Spacetime
Creators: name: Kumara, A. Naveena
name: Rizwan, C. L. Ahmed
name: Hegde, Kartheek
name: M, Ajith K.
Publisher: name: arXiv
Year: 2020
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study the interaction between the microstructures of Hayward-AdS black hole using Ruppeiner geometry. Our investigation shows that the dominant interaction between the black hole molecules is attractive in most part of the parametric space of temperature and volume, as in van der Waals system. However, in contrast to the van der Waals fluid, there exists a weak dominant repulsive interaction for small black hole phase in some parameter range. This result clearly distinguishes the interactions in a magnetically charged black hole from that of van der Waals fluid. However, these sort of interactions are characteristic for charged black holes since they do not dependent on magnetic charge or temperature.
description: 14 pages, 5 figures. Version accepted for publication on Physics Letters B
Austrothaumalea commoni Theischinger 1986
Creators: name: Sinclair, Bradley J.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Thaumaleidae
Austrothaumalea
Austrothaumalea commoni

description: Austrothaumalea commoni Theischinger
 Austrothaumalea commoni Theischinger, 1986: 300.
 Material examined. New South Wales: 1 ?, Kosciusko NP, Thredbo, roadcut seeps, 1300 m, 28.xi.1994 (AMS).
 Distribution. This species is known from southeastern New South Wales.
description: Published as part of Sinclair, Bradley J., 2008, New Species of Austrothaumalea Tonnoir from Australia (Diptera: Thaumaleidae), pp. 1-12 in Records of the Australian Museum 60 (1) on page 6, DOI: 10.3853/j.0067-1975.60.2008.1490, http://zenodo.org/record/4676495
Three Essays on Credit Card Debt
Creators: name: Leszczyszyn, Natalia
Publisher: name: American University
Year: 2023

description: This dissertation provides insight into consumers’ use of credit cards. Chapter 2 presents a simple life-cycle model that highlights how time inconsistency, naiveté and financial literacy influence consumers’ lifetime consumption paths. The model demonstrates how payment mechanisms that decouple payment and consumption incline consumers to give into behavioral influences. It first displays how credit cards tempt consumers with time inconsistent preferences to overspend early on in life. It then uses a mental accounting framework to show that consumers who overlook the cost of credit or do not consider their long-term financial well-being exhaust their available credit. Chapter 3 takes a closer look at consumers’ perceptions of the cost of credit. While several studies conclude that consumers with low levels of financial literacy are more likely to engage in high cost borrowing, other studies indicate that financial literacy is positively related to credit card debt or that it has no impact on credit card debt. All of these studies measure financial literacy as the ability to answer multiple choice questions regarding interest rates, minimum payments and credit terms. However, these questions do not directly gauge if consumers perceive credit cards as costly. This chapter contributes to the literature by showing that consumers who hold more credit card debt perceive cards as a costly payment mechanism. However, I find limited evidence that consumers who perceive credit cards as costly respond by paying down on their balances. Instead, consumers who adopt additional credit cards make use of the increase in credit. Chapter 4 investigates the “credit card debt puzzle.” Simultaneously holding high cost credit card debt and liquid assets is puzzling given the significant difference between interest rates. However, this behavior is common –about 31% of households in the 2016 Survey of Consumer Finances. The cost of co-holding may be justified if consumers anticipate future restrictions in credit or if they need to maintain liquidity. Other existing explanations for co-holding include impulsive spending and low financial literacy. Using a Coarsened Exact Matching method, we find that overconfident consumers are 20%-40% more likely to co-hold credit card debt and liquid assets.
Additional file 9 of Exercising with Baxter: preliminary support for assistive social-physical human-robot interaction
Creators: name: Fitter, Naomi T.
name: Mohan, Mayumi
name: Kuchenbecker, Katherine J.
name: Johnson, Michelle J.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 9 Gameplay flow of the Strength Game.
Skyrmions, Quantum Hall Droplets, and one current to rule them all
Creators: name: Karasik, Avner
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We introduce a novel Skyrme-like conserved current in the effective theory of pions and vector mesons based on the idea of hidden local symmetry. The associated charge is equivalent to the skyrmion charge for any smooth configuration. In addition, there exist singular configurations that can be identified as N_f=1 baryons charged under the new symmetry. Under this identification, the vector mesons play the role of the Chern-Simons vector fields living on the quantum Hall droplet that forms the N_f=1 baryon. We propose that this current is the correct effective expression for the baryon current at low energies. This proposal gives a unified picture for the two types of baryons and allows them to continuously transform one to the other in a natural way. In addition, Chern-Simons dualities on the droplet can be interpreted as a result of Seiberg-like duality between gluons and vector mesons.
description: Minor changes
Lack of self-averaging of the specific heat in the three-dimensional random-field Ising model
Creators: name: Malakis, Anastasios
name: Fytas, Nikolaos G.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We apply the recently developed critical minimum energy subspace scheme for the investigation of the random-field Ising model. We point out that this method is well suited for the study of this model. The density of states is obtained via the Wang-Landau and broad histogram methods in a unified implementation by employing the N-fold version of the Wang-Landau scheme. The random-fields are obtained from a bimodal distribution ($h_{i}=\pm2$), and the scaling of the specific heat maxima is studied on cubic lattices with sizes ranging from $L=4$ to $L=32$. Observing the finite-size scaling behavior of the maxima of the specific heats we examine the question of saturation of the specific heat. The lack of self-averaging of this quantity is fully illustrated and it is shown that this property may be related to the question mentioned above.
description: 8 pages, 7 figures, extended version with two new figures, version as accepted for publication to Physical Review E
Entwicklungsaufgaben im Vorbereitungsdienst
Creators: name: Keller-Schneider, Manuela
Publisher: name: Zenodo
Year: 2021
Subjects: Referendariat
pädagogische Ausbildung
fachdidaktische Ausbildung
Unterrichtspraxis
unterrichtspraktische Kompetenz
Lehrperson

description: Aus der Einleitung dieses Sammelbandbeitrags «In der zweiphasigen Lehrerinnen- und Lehrerbildung in Deutschland übernimmt das Referendariat als zweite Phase die schulfeldbezogene Ausbildungsfunktion und wird einem dualistischen Modell folgend von zwei Institutionen verantwortet. Im Studienseminar wird pädagogisches und fachdidaktisches Wissen vertieft, in der Ausbildungsschule steht die Weiterentwicklung der unterrichtspraktischen Kompetenz im Zentrum. Die Auseinandersetzung mit schulfeldbezogenen Anforderungen erfolgt in zunehmender Selbständigkeit, beginnt mit Hospitation, gefolgt von angeleitetem bis hin zu selbstständigem Unterrichten und wird von Ausbilderinnen und Ausbildern beider Institutionen beurteilt. Bedingt durch den Ausbildungskontext und die damit einhergehende Beurteilung richtet sich die Selbstständigkeit nach dem Referenzrahmen der implizit und explizit an die Unterrichtstätigkeit gestellten Erwartungen beider Institutionen sowie ihrer Akteurinnen und Akteure. Damit wird der Rahmen möglicher Erkundungen und Erprobungen eingegrenzt; wie damit umgegangen wird, variiert. Der folgende Beitrag geht der Frage nach, wie sich berufsphasenspezifische Entwicklungsaufgaben und der Umgang damit konkretisieren lassen. Nach Ausführungen zur entwicklungspsychologischen Begründung von Entwicklungsaufgaben folgen Erläuterungen zu den beruflichen Entwicklungsaufgaben des Lehrberufs, ihrer Wahrnehmung sowie ihren berufsphasenspezifischen Konkretisierungen. Anschließend wird die spezifische Situation im Referendariat beleuchtet. Der Beitrag schließt mit einem Reflexionsinstrument zur Analyse erlebter Unterrichtssituationen, um das dynamische Ganze aus den Perspektiven der vier beruflichen Entwicklungsaufgaben zu reflektieren.» [189] → der Volltext dieses Beitrags ist innerhalb des PHZH-Netzwerks mit diesem Link zugänglich
description: +repphzhbib2021A
Three Essays on Credit Card Debt
Creators: name: Leszczyszyn, Natalia
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 38
subject: Economics

description: This dissertation provides insight into consumers’ use of credit cards. Chapter 2 presents a simple life-cycle model that highlights how time inconsistency, naiveté and financial literacy influence consumers’ lifetime consumption paths. The model demonstrates how payment mechanisms that decouple payment and consumption incline consumers to give into behavioral influences. It first displays how credit cards tempt consumers with time inconsistent preferences to overspend early on in life. It then uses a mental accounting framework to show that consumers who overlook the cost of credit or do not consider their long-term financial well-being exhaust their available credit. Chapter 3 takes a closer look at consumers’ perceptions of the cost of credit. While several studies conclude that consumers with low levels of financial literacy are more likely to engage in high cost borrowing, other studies indicate that financial literacy is positively related to credit card debt or that it has no impact on credit card debt. All of these studies measure financial literacy as the ability to answer multiple choice questions regarding interest rates, minimum payments and credit terms. However, these questions do not directly gauge if consumers perceive credit cards as costly. This chapter contributes to the literature by showing that consumers who hold more credit card debt perceive cards as a costly payment mechanism. However, I find limited evidence that consumers who perceive credit cards as costly respond by paying down on their balances. Instead, consumers who adopt additional credit cards make use of the increase in credit. Chapter 4 investigates the “credit card debt puzzle.” Simultaneously holding high cost credit card debt and liquid assets is puzzling given the significant difference between interest rates. However, this behavior is common –about 31% of households in the 2016 Survey of Consumer Finances. The cost of co-holding may be justified if consumers anticipate future restrictions in credit or if they need to maintain liquidity. Other existing explanations for co-holding include impulsive spending and low financial literacy. Using a Coarsened Exact Matching method, we find that overconfident consumers are 20%-40% more likely to co-hold credit card debt and liquid assets.
Additional file 1 of The sweet spot: fasting glucose, cardiovascular disease, and mortality in older adults with diabetes: a nationwide population-based study
Creators: name: Lee, Ji Hyun
name: Kyungdo Han
name: Huh, Ji Hye
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1. Study population.
A Characterization of Cross-generational THC Exposure and Offspring Responsivity to Cocaine, Nicotine and Opiates
Creators: name: Hempel, Briana Janel
Publisher: name: American University
Year: 2023

description: An emerging area of preclinical research has investigated whether drug use in parents prior to conception influences drug responsivity in their offspring. The present work sought to further characterize such effects with cannabis by examining whether a parental THC history modified locomotor sensitization to and self-administration of cocaine (Experiment 1), nicotine (Experiment 2) and opiates (Experiment 3) in adult progeny. Adolescent male and female Sprague Dawley rats were administered 1.5 mg/kg THC or vehicle every 3rd day during PND 28-49. On PND 65, males and females within the same dose group were bred together and the resultant pups cross fostered to control dams. In Experiment 1A, a baseline activity monitoring session was run followed by 7 days of cocaine injections during which subjects (male) from these breeding pairs were placed in activity chambers. After a 7-day washout period, a challenge dose of cocaine was administered and subjects were again monitored. In Experiment 1B, F1 subjects were implanted with a jugular catheter and underwent cocaine self-administration (FR1, FR5, FR10, PR, dose response assessment, extinction, cue- + stress-induced reinstatement). Cocaine induced a significant increase in behavioral sensitization and maintained responding across the various reinforcement schedules. There was no consistent effect of parental THC exposure on any endpoint assessed. In Experiments 2 and 3, similar locomotor sensitization and IVSA parameters were utilized (using male and females). Locomotor sensitization with nicotine and morphine was unaffected by germline THC exposure. While nicotine self-administration was only marginally affected, F1-THC males displayed a reduced motivation to self-administer heroin compared to F1-Veh males. The present data indicate that parental THC exposure alters the reinforcing properties of abused drugs in a drug- and sex-specific manner. As such, mild to moderate cannabis use during adolescence may alter heroin abuse liability for males in the subsequent generation, but have limited effects on cocaine and nicotine.
TaskNorm: Rethinking Batch Normalization for Meta-Learning
Creators: name: Bronskill, John
name: Gordon, Jonathan
name: Requeima, James
name: Nowozin, Sebastian
name: Turner, Richard E.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Modern meta-learning approaches for image classification rely on increasingly deep networks to achieve state-of-the-art performance, making batch normalization an essential component of meta-learning pipelines. However, the hierarchical nature of the meta-learning setting presents several challenges that can render conventional batch normalization ineffective, giving rise to the need to rethink normalization in this setting. We evaluate a range of approaches to batch normalization for meta-learning scenarios, and develop a novel approach that we call TaskNorm. Experiments on fourteen datasets demonstrate that the choice of batch normalization has a dramatic effect on both classification accuracy and training time for both gradient based and gradient-free meta-learning approaches. Importantly, TaskNorm is found to consistently improve performance. Finally, we provide a set of best practices for normalization that will allow fair comparison of meta-learning algorithms.
A Characterization of Cross-generational THC Exposure and Offspring Responsivity to Cocaine, Nicotine and Opiates
Creators: name: Hempel, Briana Janel
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: An emerging area of preclinical research has investigated whether drug use in parents prior to conception influences drug responsivity in their offspring. The present work sought to further characterize such effects with cannabis by examining whether a parental THC history modified locomotor sensitization to and self-administration of cocaine (Experiment 1), nicotine (Experiment 2) and opiates (Experiment 3) in adult progeny. Adolescent male and female Sprague Dawley rats were administered 1.5 mg/kg THC or vehicle every 3rd day during PND 28-49. On PND 65, males and females within the same dose group were bred together and the resultant pups cross fostered to control dams. In Experiment 1A, a baseline activity monitoring session was run followed by 7 days of cocaine injections during which subjects (male) from these breeding pairs were placed in activity chambers. After a 7-day washout period, a challenge dose of cocaine was administered and subjects were again monitored. In Experiment 1B, F1 subjects were implanted with a jugular catheter and underwent cocaine self-administration (FR1, FR5, FR10, PR, dose response assessment, extinction, cue- + stress-induced reinstatement). Cocaine induced a significant increase in behavioral sensitization and maintained responding across the various reinforcement schedules. There was no consistent effect of parental THC exposure on any endpoint assessed. In Experiments 2 and 3, similar locomotor sensitization and IVSA parameters were utilized (using male and females). Locomotor sensitization with nicotine and morphine was unaffected by germline THC exposure. While nicotine self-administration was only marginally affected, F1-THC males displayed a reduced motivation to self-administer heroin compared to F1-Veh males. The present data indicate that parental THC exposure alters the reinforcing properties of abused drugs in a drug- and sex-specific manner. As such, mild to moderate cannabis use during adolescence may alter heroin abuse liability for males in the subsequent generation, but have limited effects on cocaine and nicotine.
Quasi-Supersymmetric $G^3$ Unification from Intersecting D6-Branes on Type IIA Orientifolds
Creators: name: Li, Tianjun
name: Liu, Tao
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We construct three quasi-supersymmetric $G^3$ GUT models with $S_3$ symmetry and gauge coupling unification from intersecting D6-branes on Type IIA orientifolds. The Standard Model fermions and Higgs doublets can be embedded into the bifundamental representations in these models, and there is no any other unnecessary massless representation. Especially in Model I with gauge group $U(4)^3$, we just have three-family SM fermions and three pairs of Higgs particles. The $G^3$ gauge symmetry in these models can be broken down to the Standard Model gauge symmetry by introducing light open string states. And 1 TeV scale supersymmetry breaking soft masses imply the reasonable intermediate string scale.
description: Latex, 14 pages, typos fixed, version to appear in PLB
Time-like T-duality algebra
Creators: name: Keurentjes, Arjan
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: When compactifying M- or type II string-theories on tori of indefinite space-time signature, their low energy theories involve sigma models on E_{n(n)}/H_n, where H_n is a not necessarily compact subgroup of E_{n(n)} whose complexification is identical to the complexification of the maximal compact subgroup of E_{n(n)}. We discuss how to compute the group H_n. For finite dimensional E_{n(n)}, a formula derived from the theory of real forms of E_n algebra's gives the possible groups immediately. A few groups that have not appeared in the literature are found. For n=9,10,11 we compute and describe the relevant real forms of E_n and H_n. A given H_n can correspond to multiple signatures for the compact torus. We compute the groups H_n for all compactifications of M-, M*-, and M'-theories, and type II-, II*- and II'-theories on tori of arbitrary signature, and collect them in tables that outline the dualities between them. In an appendix we list cosets G/H, with G split and H a subgroup of G, that are relevant to timelike toroidal compactifications and oxidation of theories with enhanced symmetries.
description: LaTeX, 37 pages, 1 eps-figure, uses JHEP.cls; v2. corrected typo's in tables 16 and 17, minor changes to text
Inside the Lion Cage
Creators: name: Dyal, Danielle
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 3602
subject: Creative and professional writing

description: Inside the Lion Cage is an original novel that follows a Guyanese-American family—specifically, mother, Manisha, and son, Sammy—after a kidnapping shocks the Pennsylvanian suburb in which they live. The kidnapping, along with the sudden reappearance of Manisha’s illicit ex-lover—the teenage son of her best friend—leads to the resurfacing of Manisha’s dark psyche that she previously suppressed to attempt a “normal” suburban family life. Meanwhile, Sammy is confronted with his own moral dilemmas when presented with the chance to save the kidnapped girl. This novel explores the repercussions of being a social outsider in a conformist community and examines different types of resulting deviance—the harmless deviance that challenges arbitrary norms and the dangerous deviance that rejects ethical behavior and embraces the wicked.
An investigation into a CIRS style Solar Aquatic System at the UBC Farm
Creators: name: Chow, Kevin
name: Fong, Andrew
name: Wong, Ka Fai (Philip)
Publisher: name: The University of British Columbia
Year: 2014

description: The purpose of this study was to evaluate the impacts of installing a Solar Aquatic System for water treatment similar to the one in use at the UBC Centre for Interactive Research on Sustainability. The system should purify water, making it suitable for irrigation, fertigation, aquaculture, and other purposes (not for drinking). We analyzed economic, environmental, and social factors to determine whether the construction of such a system would be in the best interest of the UBC Farm and UBC as a whole. We found that the SAS was a good solution when taking into account all economic factors. Although the short-term cost of capital investment and operation costs were high, the fact that the SAS could be expanded to filter a higher capacity as the population of the south campus increases in the future was one of the determining factors when determining the economics involved. We also found that it met the environmental requirements. The Fecal coliforms were reduced to less than 200 colonies/100mL, estrogen and endocrine disruptor levels were reduced by between 93-95%, nitrogen levels and phosphorus levels are reduced by 98.7% and 97% respectively, and heavy metals were found to be reduced to acceptable levels by being absorbed by certain kinds of plants. The remaining pollutant levels in the effluent of the system were low enough that it could be used for irrigation, fertigation, aquaculture, and other agricultural purposes, but not for human consumption, as the water does not meet the drinking water standards. The SAS system is good from a social point of view because it has a positive effect on education. It improves students’ learning attitude and provides a better environment for students to learn. It also helps UBC to be agent of change, and as a leader of green in Canada. However, the construction may disturb people who are living near that area, and people are afraid of buying the crops that are irrigated by the treated wastewater. Overall, we recommend the installation of a CIRS style SAS system at the new UBC Farm building due to these benefits. Disclaimer: “UBC SEEDS provides students with the opportunity to share the findings of their studies, as well as their opinions, conclusions and recommendations with the UBC community. The reader should bear in mind that this is a student project/report and is not an official document of UBC. Furthermore readers should bear in mind that these reports may not reflect the current status of activities at UBC. We urge you to contact the research persons mentioned in a report or the SEEDS Coordinator about the current status of the subject matter of a project/report.”
Inside the Lion Cage
Creators: name: Dyal, Danielle
Publisher: name: American University
Year: 2023

description: Inside the Lion Cage is an original novel that follows a Guyanese-American family—specifically, mother, Manisha, and son, Sammy—after a kidnapping shocks the Pennsylvanian suburb in which they live. The kidnapping, along with the sudden reappearance of Manisha’s illicit ex-lover—the teenage son of her best friend—leads to the resurfacing of Manisha’s dark psyche that she previously suppressed to attempt a “normal” suburban family life. Meanwhile, Sammy is confronted with his own moral dilemmas when presented with the chance to save the kidnapped girl. This novel explores the repercussions of being a social outsider in a conformist community and examines different types of resulting deviance—the harmless deviance that challenges arbitrary norms and the dangerous deviance that rejects ethical behavior and embraces the wicked.
The nature of the Galactic Center source IRS 13 revealed by high spatial resolution in the infrared
Creators: name: Maillard, J. P.
name: Paumard, T.
name: Stolovy, S. R.
name: Rigaut, F.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: High spatial resolution observations in the 1 to 3.5 micron region of the Galactic Center source known historically as IRS 13 are presented. They include ground-based adaptive optics images in the H, Kp (2.12/0.4 micron) and L bands, NICMOS data in filters between 1.1 and 2.2 micron, and integral field spectroscopic data from BEAR, an Imaging FTS, in the HeI 2.06 micron and the Br$γ$ line regions. Analysis of all these data provides a completely new picture of the main component, IRS 13E, which appears as a cluster of seven individual stars within a projected diameter of ~0.5'' (0.02 pc). The brightest sources, 13E1, 13E2, 13E3 (a binary), and 13E4, are all massive stars, 13E1 a blue object, with no detected emission line while 13E2 and 13E4 are high-mass emission line stars. 13E2 is at the WR stage and 13E4 a massive O-type star. 13E3A and B are extremely red objects, proposed as other examples of dusty WR stars. All these sources have a common westward proper motion. 13E5, is a red source similar to 13E3A/B. This concentration of comoving massive hot stars, IRS 13E, is proposed as the remaining core of a massive star cluster, which could harbor an intermediate-mass black hole (IMBH) of ~1300 M_sol. This detection plays in favor of a scenario in which the helium stars and the other hot stars in the central pc originate from the stripping of a massive cluster formed several tens of pc from the center. The detection of a discrete X-ray emission (Baganoff et al. 2003) at the IRS~13 position is examined in this context.
description: 14 pages, 6 figures (3 in color), LaTeX2e, accepted in A&A
Additional file 1 of Role of human papillomavirus infection in the etiology of vulvar cancer in Italian women
Creators: name: Preti, Mario
name: Rotondo, John Charles
name: Holzinger, Dana
name: Micheletti, Leonardo
name: Gallio, Niccolò
name: McKay-Chopin, Sandrine
name: Carreira, Christine
name: Privitera, Sebastiana Silvana
name: Watanabe, Reiko
name: Ruediger Ridder
name: Pawlita, Michael
name: Benedetto, Chiara
name: Tommasino, Massimo
name: Gheit, Tarik
Publisher: name: figshare
Year: 2020
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Table S1. HPV DNA, HPV RNA and p16 status in 102 VSCC and 7 MTS individual cases.