cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Differential contractile response of critically ill patients to neuromuscular electrical stimulation
Creators: name: Grunow, Julius J.
name: Goll, Moritz
name: Carbon, Niklas M.
name: Liebl, Max E.
name: Weber-Carstens, Steffen
name: Wollersheim, Tobias
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: Critical illness
subject: Critical illness myopathy
subject: Early mobilisation
subject: Intensive care unit-acquired weakness
subject: Neuromuscular electrical stimulation
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: BACKGROUND: Neuromuscular electrical stimulation (NMES) has been investigated as a preventative measure for intensive care unit-acquired weakness. Trial results remain contradictory and therefore inconclusive. As it has been shown that NMES does not necessarily lead to a contractile response, our aim was to characterise the response of critically ill patients to NMES and investigate potential outcome benefits of an adequate contractile response. METHODS: This is a sub-analysis of a randomised controlled trial investigating early muscle activating measures together with protocol-based physiotherapy in patients with a SOFA score ≥ 9 within the first 72 h after admission. Included patients received protocol-based physiotherapy twice daily for 20 min and NMES once daily for 20 min, bilaterally on eight muscle groups. Electrical current was increased up to 70 mA or until a contraction was detected visually or on palpation. Muscle strength was measured by a blinded assessor at the first adequate awakening and ICU discharge. RESULTS: One thousand eight hundred twenty-four neuromuscular electrical stimulations in 21 patients starting on day 3.0 (2.0/6.0) after ICU admission were included in this sub-analysis. Contractile response decreased from 64.4% on day 1 to 25.0% on day 7 with a significantly lower response rate in the lower extremities and proximal muscle groups. The electrical current required to elicit a contraction did not change over time (day 1, 50.2 [31.3/58.8] mA; day 7, 45.3 [38.0/57.5] mA). The electrical current necessary for a contractile response was higher in the lower extremities. At the first awakening, patients presented with significant weakness (3.2 [2.5/3.8] MRC score). When dividing the cohort into responders and non-responders (> 50% vs. ≤ 50% contractile response), we observed a significantly higher SOFA score in non-responders. The electrical current necessary for a muscle contraction in responders was significantly lower (38.0 [32.8/42.9] vs. 54.7 [51.3/56.0] mA, p
The Work of Behram Kursunoglu
Creators: name: Mannheim, Philip D.
Publisher: name: arXiv
Year: 2004
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Talk presented at the 2003 Coral Gables conference in honor and appreciation of the work of Professor Behram Kursunoglu, general relativist extraordinaire and founder of the Coral Gables series of conferences, whose untimely death occurred shortly before the 2003 conference.
description: 8 pages, latex using ws-procs9x6.cls, talk presented at the 2003 Coral Gables conference
Additional file 1 of Effects of environmental modification on the diversity and positivity of anopheline mosquito aquatic habitats at Arjo-Dedessa irrigation development site, Southwest Ethiopia
Creators: name: Dawit Hawaria
name: Assalif Demissew
name: Kibret, Solomon
name: Ming-Chieh Lee
name: Delenasaw Yewhalaw
name: Guiyun Yan
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Computational Biology

description: Additional file 1 : Table S1 Logistic regression analysis for anopheline larvae occurrence, around Arjo-Dedessa sugar development site, southwest Ethiopia (2017â€“2018)
Improving the locality of the overlap Dirac operator via approximate solutions of the Ginsparg-Wilson relation
Creators: name: Adams, David H.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We determine the free field hypercubic Dirac operator which is optimally close to satisfying the Ginsparg-Wilson relation. Inserting this operator into the overlap formula, we show that the analytic locality bound on the resulting overlap Dirac operator is substantially stronger than in the standard case. This improvement generally persists in gauge backgrounds when the plaquette variables are all close to unity.
description: 3 pages, contributed to Proceedings of Lattice2003(chiral)
Additional file 3 of Comorbidity prevalence among cancer patients: a population-based cohort study of four cancers
Creators: name: Fowler, Helen
name: Belot, Aurelien
name: Ellis, Libby
name: Maringe, Camille
name: Luque-Fernandez, Miguel
name: Njagi, Edmund
name: Navani, Neal
name: Sarfati, Diana
name: Rachet, Bernard
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Additional file 3. Probability (%) of condition present as single or multiple comorbidity, by deprivation group (rectal cancer). Additional results in complement to those presented in Fig. 3: graphs representing the probability of having any of nine comorbid conditions in rectal cancer patients.
Additional file 6 of Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components
Creators: name: Lindner, Paula
name: Christensen, Søren
name: Nissen, Poul
name: Møller, Jesper
name: Engedal, Nikolai
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 5: Figure S12. Tg-mediated upregulation of DR5- and LC3B mRNA levels requires PERK, ATF4 and CHOP in LNCaP and HCT116 cells. Figure S13. IRE1 and ATF6 knockdown confirmations (related to Fig. 5). Figure S14. Tg-mediated caspase activation and upregulation of DR5 and LC3B does not require IRE1, XBP1, ATF6, or JNK in HCT116 cells. Figure S15. Tg rapidly enhances XBP1s mRNA levels in an IRE1-dependent manner in LNCaP cells (related to Fig. 8). Figure S16. Cell death induced by the therapeutically relevant Tg analogs Leu-8ADT and βAsp-8ADT requires DR5 and caspase-8 in LNCaP and HCT116 cells, and partially requires FADD and Fas in LNCaP cells, whereas DR4 and TRADD are not required in any of the cell lines. Figure S17. Cell death induced by Leu-8ADT and βAsp-8ADT requires PERK, ATF4, and CHOP in LNCaP and HCT116 cells. Figure S18. Cell death induced by Leu-8ADT and βAsp-8ADT involves IRE1, XBP1, and JNK in LNCaP, but not HCT116 cells.
Cheumatopsyche amboinica
Creators: name: Oláh, János
name: Johanson, Kjell Arne
name: Barnard, Peter C.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Hydropsychidae
Cheumatopsyche
Cheumatopsyche amboinica

description: Cheumatopsyche amboinica (Navás, 1928)
 Hydropsychodes amboinica Navás, 1928: 112.
 Cheumatopsyche amboinica (Navás, 1928); Kimmins 1963: 130.
 Type locality: Africa (“Amboni”).
description: Published as part of Oláh, János, Johanson, Kjell Arne & Barnard, Peter C., 2008, Revision of the Oriental and Afrotropical species of Cheumatopsyche Wallengren (Hydropsychidae, Trichoptera), pp. 1-171 in Zootaxa 1738 on page 157
Finite automorphisms of negatively curved Poincare Duality groups
Creators: name: Farrell, F. T.
name: Lafont, J. -F.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Group Theory (math.GR)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: In this paper, we show that if G is a finite p-group (p prime) acting by automorphisms on a $δ$-hyperbolic Poincare Duality group, then the fixed subgroup is a Poincare Duality group over Z/p. We also provide examples to show that the fixed subgroup might not even be a Duality group over Z.
description: 11 pages, 1 figure; revised version has shorter proof for Prop 2.1; appeared in Geom. Funct. Anal. 14 (2004), pgs. 283-294
Detection of CD33 expression on monocyte surface is influenced by phagocytosis and temperature
Creators: name: Suwannasom, Nittiya
name: Smuda, Kathrin
name: Kloypan, Chiraphat
name: Kaewprayoon, Waraporn
name: Baisaeng, Nuttakorn
name: Boonla, Chanchai
name: Georgieva, Radostina
name: Bäumler, Hans
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: CD33
subject: Expression
subject: Pre-analytical conditions
subject: Internalisation
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: CD33 is a myeloid-associated marker and belongs to the sialic acid-binding immunoglobulin (Ig)-like lectin (Siglec) family. Such types of receptors are highly expressed in acute myeloid leukemia, which could be used in its treatment. CD33 shows high variability in its expression levels with still unknown reasons. Here, we investigated the CD33 expression of monocytes in human blood samples processed at different temperatures and in dependence on their phagocytic activity against opsonized Escherichia coli. The samples were stained by fluorescently labelled anti-human CD14 to specify the monocyte population, anti-human CD33 antibodies to evaluate CD33 expression and analyzed by flow cytometry and confocal laser scanning microscopy. In blood samples kept at 37°C or first pre-chilled at 0°C with subsequent warming up to 37°C, the percentage of CD33-positive monocytes as well as their relative fluorescence intensity was up-regulated compared to samples kept constantly at 0°C. After exposure to E. coli the CD33 relative fluorescence intensity of the monocytes activated at 37°C was 3 to 4 times higher than that of those cells kept inactive at 0°C. Microscopic analysis showed internalisation of CD33 due to its enhanced expression on the surface followed by engulfment of E. coli.
Cheumatopsyche capitata Navas 1936
Creators: name: Oláh, János
name: Johanson, Kjell Arne
name: Barnard, Peter C.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Hydropsychidae
Cheumatopsyche
Cheumatopsyche capitata

description: Cheumatopsyche capitata Navás, 1936
 Cheumatopsyche capitata Navás, 1936: 131.
 Type locality: China (Sichuan).
description: Published as part of Oláh, János, Johanson, Kjell Arne & Barnard, Peter C., 2008, Revision of the Oriental and Afrotropical species of Cheumatopsyche Wallengren (Hydropsychidae, Trichoptera), pp. 1-171 in Zootaxa 1738 on page 158
Development of probiotic orodispersible tablets using mucoadhesive polymers for buccal mucoadhesion
Creators: name: Hoffmann, Anja
name: Joerg T. Fischer
name: Daniels, Rolf
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Hematology
subject: Computational Biology

description: Probiotic bacteria, such as different lactobacilli strains, have successfully been used to treat gingivitis and periodontitis or caries. By formulating probiotics as orodispersible tablet (ODT), the benefits of this dosage form could be utilized. Without any further measures, the probiotic bacteria will be eliminated too fast from the intended site of action, the oral mucosa. The use of mucoadhesive granules, composed of mucoadhesive polymer and probiotics, is a promising strategy to prolong the contact time between lactobacilli and oral mucosa without delaying disintegration. Three common mucoadhesive polymers, anionic Carbopol 971P NF, nonionic Metolose 65SH50 and cationic chitosan were included into tablets either by direct compression (DC) or after granulation with the probiotics. Disintegration, mucoadhesion of the tablets, and storage stability of the probiotics were characterized. By incorporating a sufficient amount of polymer superior probiotic mucoadhesion could be achieved. All formulations based on granulated probiotics and mucoadhesive polymer fulfilled the Food and Drug Administration (FDA) acceptance level for disintegration of orodispersible tablets. These formulations exhibited excellent storage stability under refrigerated conditions over 30 months. Interestingly, ODTs including Carbopol 971P NF still proved superior mucoadhesion after long-term storage, whereas the mucoadhesive effect of Metolose 65SH50 and chitosan declined markedly. The results of this study suggest that Carbopol 971P NF was the most appropriate polymer for a probiotic mucoadhesive ODT.
Alveolar Dynamics and Beyond – The Importance of Surfactant Protein C and Cholesterol in Lung Homeostasis and Fibrosis
Creators: name: Sehlmeyer, Kirsten
name: Ruwisch, Jannik
name: Roldan, Nuria
name: Lopez-Rodriguez, Elena
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: surfactant protein C
subject: pulmonary fibrosis
subject: alveolar dynamics
subject: lipid metabolism
subject: alveolar macrophages
subject: cholesterol
subject: metaflammation
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Surfactant protein C (SP-C) is an important player in enhancing the interfacial adsorption of lung surfactant lipid films to the alveolar air-liquid interface. Doing so, surface tension drops down enough to stabilize alveoli and the lung, reducing the work of breathing. In addition, it has been shown that SP-C counteracts the deleterious effect of high amounts of cholesterol in the surfactant lipid films. On its side, cholesterol is a wellknown modulator of the biophysical properties of biological membranes and it has been proven that it activates the inflammasome pathways in the lung. Even though the molecular mechanism is not known, there are evidences suggesting that these two molecules may interplay with each other in order to keep the proper function of the lung. This review focuses in the role of SP-C and cholesterol in the development of lung fibrosis and the potential pathways in which impairment of both molecules leads to aberrant lung repair, and therefore impaired alveolar dynamics. From molecular to cellular mechanisms to evidences in animal models and human diseases. The evidences revised here highlight a potential SP-C/cholesterol axis as target for the treatment of lung fibrosis.
Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4+ CAR T Cell Efficacy
Creators: name: Ali, Solin
name: Toews, Karin
name: Schwiebert, Silke
name: Klaus, Anika
name: Winkler, Annika
name: Grunewald, Laura
name: Oevermann, Lena
name: Deubzer, Hedwig E.
name: Tüns, Alicia
name: Jensen, Michael C.
name: Henssen, Anton George
name: Eggert, Angelika
name: Schulte, Johannes Hubertus
name: Schwich, Esther
name: Rebmann, Vera
name: Schramm, Alexander
name: Künkele, Annette
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: immunotherapy
subject: pediatric oncology
subject: neuroblastoma
subject: solid tumors
subject: neurotrophic receptor tyrosine kinase
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Chimeric antigen receptor (CAR) T cell efficacy against solid tumors is currently limited by several immune escape mechanisms, which may include tumor-derived extracellular vesicles. Advanced neuroblastoma is an aggressive childhood tumor without curative treatment options for most relapsed patients today. We here evaluated the role of tumor-derived extracellular vesicles on the efficacy of CAR T cells targeting the neuroblastoma-specific antigen, CD171. For this purpose, CAR T cell activation, cytokine production, exhaustion, and tumor cell-directed cytotoxicity upon co-culture was evaluated. Tumor-derived extracellular vesicles isolated from SH-SY5Y neuroblastoma cells neither affected CAR T cell activation nor expression of inhibitory markers. Importantly, exposure of CD4+ CD171-specific CAR T cells to tumor-derived extracellular vesicles significantly impaired tumor cytotoxicity of CAR T cells. This effect was independent of neurotrophic receptor tyrosine kinases 1 or 2 (NTRK1, NTRK2) expression, which is known to impact immune responses against neuroblastoma. Our results demonstrate for the first time the impact of tumor-derived extracellular vesicles and non-cell-mediated tumor-suppressive effects on CD4+ CAR T cell efficacy in a preclinical setting. We conclude that these factors should be considered for any CAR T cell-based therapy to make CAR T cell therapy successful against solid tumors.
Quantum sensing with a single-qubit pseudo-Hermitian system
Creators: name: Chu, Yaoming
name: Liu, Yu
name: Liu, Haibin
name: Cai, Jianming
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum sensing exploits fundamental features of quantum system to achieve highly efficient measurement of physical quantities. Here, we propose a strategy to realize a single-qubit pseudo-Hermitian sensor from a dilated two-qubit Hermitian system. The pseudo-Hermitian sensor exhibits divergent susceptibility in dynamical evolution that does not necessarily involve exceptional point. We demonstrate its potential advantages to overcome noises that cannot be averaged out by repetitive measurements. The proposal is feasible with the state-of-art experimental capability in a variety of qubit systems, and represents a step towards the application of non-Hermitian physics in quantum sensing.
description: 6 pages, 3 figure, comments are welcome
N=1* model and glueball superpotential from Renormalization-Group-improved perturbation theory
Creators: name: Arnone, Stefano
name: Guerrieri, Francesco
name: Yoshida, Kensuke
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A method for computing the low-energy non-perturbative properties of SUSY GFT, starting from the microscopic lagrangian model, is presented. The method relies on covariant SUSY Feynman graph techniques, adapted to low energy, and Renormalization-Group-improved perturbation theory. We apply the method to calculate the glueball superpotential in N=1 SU(2) SYM and obtain a potential of the Veneziano-Yankielowicz type.
description: 19 pages, no figures; added references; note added at the end of the paper; version to appear in JHEP
Development of probiotic orodispersible tablets using mucoadhesive polymers for buccal mucoadhesion
Creators: name: Hoffmann, Anja
name: Joerg T. Fischer
name: Daniels, Rolf
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Computational Biology

description: Objective: Probiotic bacteria, such as different lactobacilli strains, have successfully been used to treat gingivitis and periodontitis or caries. By formulating probiotics as orodispersible tablet (ODT), the benefits of this dosage form could be utilised. Without any further measures, the probiotic bacteria will be eliminated too fast from the intended site of action, the oral mucosa. The use of mucoadhesive granules, composed of mucoadhesive polymer and probiotics, is a promising strategy to prolong the contact time between lactobacilli and oral mucosa without prolonging disintegration. Methods: Three common mucoadhesive polymers, anionic Carbopol 971P NF, non-ionic Metolose 65SH50 and cationic chitosan were included into tablets either by direct compression (DC) or after granulation with the probiotics. Disintegration, mucoadhesion of the tablets, and storage stability of the probiotics were characterised. Results: By incorporating a sufficient amount of polymer superior probiotic mucoadhesion could be achieved. All formulations based on granulated probiotics and mucoadhesive polymer fulfilled the Food and Drug Administration (FDA) acceptance level for disintegration of orodispersible tablets. These formulations exhibited excellent storage stability under refrigerated conditions over 30 months. Interestingly, ODTs including Carbopol 971P NF still proved superior mucoadhesion after long-term storage, whereas the mucoadhesive effect of Metolose 65SH50 and chitosan declined markedly. Conclusions: The results of this study suggest that Carbopol 971P NF was the most appropriate polymer for a probiotic mucoadhesive ODT.
Gravitational Radiation from Axisymmetric Rotational Core Collapse
Creators: name: Kotake, Kei
name: Yamada, Shoichi
name: Sato, Katsuhiko
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have done a series of two-dimensional hydrodynamic simulations of the rotational collapse of a supernova core in axisymmetry. We have employed a realistic equation of state (EOS) and taken into account electron captures and neutrino transport by the so-called leakage scheme. It is an important progress to apply the realistic EOS coupled with the microphysics to 2-D simulations for computing gravitational radiation in rotational core collapse. We have used the quadrupole formula to calculate the amplitudes and the waveforms of gravitational wave assuming the Newtonian gravity. From these computations, we have extended the conventional category of the gravitational waveforms. Our results have shown that the peak amplitudes of gravitational wave are mostly within the sensitivity range of the laser interferometers such as TAMA and first LIGO for a source at a distance of 10 kpc. Furthermore we have found that the amplitudes of the second peaks are within the detection limit of first LIGO for the source and first pointed out the importance of the detections, since they will give us the information as to the angular momentum distribution of evolved massive stars.
description: PRD accepted
Is the dark halo of our Galaxy spherical?
Creators: name: Helmi, Amina
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: It has been recently claimed that the confined structure of the debris from the Sagittarius dwarf implies that the dark-matter halo of our Galaxy should be nearly spherical, in strong contrast with predictions from cold dark-matter (CDM) simulations, where dark halos are found to have typical density axis ratios of 0.6 - 0.8. In this letter, numerical simulations are used to show that the Sagittarius streams discovered thus far are too young dynamically to be sensitive to the shape of the dark halo of the Milky Way. The data presently available are entirely consistent with a Galactic dark-matter halo that could either be oblate or prolate, with minor-to-major density axis ratios c/a as low as 0.6 within the region probed by the orbit of the Sagittarius dwarf.
description: 6 pages, 5 figures, MNRAS in press. Various changes to the discussion section, typos fixed, 2 new figures and more references added, conclusions unchanged. High-resolution figures available from http://www.astro.rug.nl/~ahelmi/research/flattening.html
Ultracold collisions in the Yb-Li mixture system
Creators: name: Schäfer, Florian
name: Konishi, Hideki
name: Bouscal, Adrien
name: Yagami, Tomoya
name: Frye, Matthew D.
name: Hutson, Jeremy M.
name: Takahashi, Yoshiro
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We report our experimental results on the collisional physics between non-S-state atoms (ytterbium (Yb), effectively a two-electron system, in the metastable ${}^3\mathrm{P}_2$ state) and S-state atoms (lithium (Li), an alkali metal, in the ground state). At low magnetic fields, by measuring inelastic interspecies collisional losses in the double quantum degenerate mixture we reveal the strong dependence of the inelastic losses on the internal spin states of both species and suppressed losses in stretched state configurations. Increasing the magnetic field up to 800 G we further investigate the magnetic field dependence of the collisional interactions. There, smoothly increasing inelastic losses are observed towards higher fields. The combined knowledge of both the magnetic field and the spin state dependence of the collisional losses of this prototypical mixture system of non-S-state and S-state atoms provides a significant step forward towards controllable impurity physics realized in the Yb-Li ultracold system.
description: 9 pages, 5 figures
Two Photon Background and the Reach of a Linear Collider for Supersymmetry in WMAP Favored Coannihilation Regions
Creators: name: Baer, Howard
name: Krupovnickas, Tadas
name: Tata, Xerxes
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A neutralino relic density in accord with WMAP measurements can be found in the minimal supergravity (mSUGRA) model in several regions of parameter space: the stau co-annihilation corridor at low m_0 and the hyperbolic branch/focus point (HB/FP) region at large m_0 at the edges of parameter space, and the bulk and Higgs boson funnel regions within. In the regions at the edge, the mass gap between the next-to-lightest SUSY particle (NLSP) and the lightest SUSY particle (LSP) becomes small, and backgrounds from $γγ\to f\bar{f}$ ($f$ is a SM fermion) become important for NLSP detection at an $e^+e^-$ linear collider. We evaluate these backgrounds from bremsstrahlung and beamstrahlung photons, and demonstrate that these do not preclude the observability of the signal for the cases where either the stau or the chargino is the NLSP. We also delineate the additional portion of the stau coannihilation region, beyond what can be accessed via a search for selectrons and smuons, that can be probed by a search for di-tau-jet events plus missing energy. The reach of a LC for SUSY in the HB/FP region is shown for an updated value of $m_t\simeq 180$ GeV as recently measured by the $DØ$ experiment.
description: 19 pages including 9 eps figures
My gun, my brother : experiences of Papua New Guinea policemen 1920 - 1960
Creators: name: Kituai, August Ibrum Kumaniari
Publisher: name: The Australian National University
Year: 1993
Subjects: subject: Police HistoryPapua New Guinea

description: This study covers forty years, 1920 - 1960. It is concerned with aspects of the social and political history of members of the Royal Papuan Constabulary and the New Guinea Native police forces when they were at the peak of their careers, and when Australian rule was confident and expanding. Rather than providing an exhaustive chronology for the institutional development of the police, the thesis attempts to link information about events, about policemen's relationships with government officers (or kiaps) and villagers to wider issues in the colonial history of Papua New Guinea and, by extension, of the Pacific Islands and elsewhere. Since their formation in the 1890s, the Royal Papuan Constabulary and the New Guinea native police force played pivotal roles in the spread of German and Australian colonial rule in Papua New Guinea. Acting as middlemen, and occupying positions without precedent in their traditional backgrounds, the policemen became the eyes, ears, spokesmen and punishers of the colonial governments at the main administrative centre and the frontier. Policemen worked willingly for the government and acted as civilizing agents of the general nupela pasin of law and order, peace and hygiene. They also assisted villagers break away (some with difficulty) from a past of cannibalism, homicide, infanticide, and isolation. Some of the methods used in securing these results were dictatorial and brutal, particularly when the rifle was the symbol and reality of much colonial expansion. The thesis brings out the corporate strength felt by the police - the sense of privileged brotherhood that bound them together and the contradictions between the actions and ideals of many of the police. It explores through specific cases the extent of and the reasons for police violence. It connects the police to their own village background, both before and after police service, and it examines the relationships between police and other villagers. In their given responsibilities - policing of minor matters, exploration, apprehension of murderers, pacification of villagers, participation in the World Wars - policemen showed exceptional skills. So much of the Administration's dirty work was done by the police that without their patience, allegiance, discipline and courage colonial rule in Papua New Guinea would have been profoundly different in form and application. At least, in their perceptions, and in the views of the villagers, policemen were the most effective and ubiquitous of the colonial agents. They consistently crossed the divide between colonial rulers and the villagers under their jurisdiction, and informed them about the new order.
Cheumatopsyche tectifera Marlier 1959
Creators: name: Oláh, János
name: Johanson, Kjell Arne
name: Barnard, Peter C.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Hydropsychidae
Cheumatopsyche
Cheumatopsyche tectifera

description: Cheumatopsyche tectifera Marlier, 1959
 Cheumatopsyche tectifera Marlier, 1959: 115.
 Type locality: São Tomé Islands.
 Remarks: The examination of the microscope slides with 2 male paratypes confirmed that this is a distinct species. The genital structures are distorted and deformed, especially affecting the understanding of the original position of digitate processes, but the shape of the harpagones clearly differentiates it from the similar species, C. digitata Mosely.
description: Published as part of Oláh, János, Johanson, Kjell Arne & Barnard, Peter C., 2008, Revision of the Oriental and Afrotropical species of Cheumatopsyche Wallengren (Hydropsychidae, Trichoptera), pp. 1-171 in Zootaxa 1738 on page 156
Vanishing theorems for locally conformal hyperkaehler manifolds
Creators: name: Verbitsky, Misha
Publisher: name: arXiv
Year: 2003
Subjects: subject: Differential Geometry (math.DG)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: Let M be a compact locally conformal hyperkaehler manifold. We prove a version of Kodaira-Nakano vanishing theorem for M. This is used to show that M admits no holomorphic differential forms, and the cohomology of the structure sheaf $H^i(O_M)$ vanishes for i>1. We also prove that the first Betti number of M is 1. This leads to a structure theorem for locally conformally hyperkaehler manifolds, describing them in terms of 3-Sasakian geometry. Similar results are proven for compact Einstein-Weyl locally conformal Kaehler manifolds.
description: 41 pages. Reference added, typing errors corrected
Additional file 2 of Approaches to multidrug-resistant organism prevention and control in long-term care facilities for older people: a systematic review and meta-analysis
Creators: name: Wong, Valerie Wing Yu
name: Huang, Ying
name: Wei, Wan In
name: Wong, Samuel Yeung Shan
name: Kwok, Kin On
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Biotechnology
Cancer
Science Policy

description: Additional file 2. Description of infection prevention and control strategies.
Integration of the Noncollinear Antiferromagnetic Metal Mn3Sn onto Ferroelectric Oxides for Electric-Field Control
Creators: name: Wang, Xiaoning
name: Feng, Zexin
name: Qin, Peixin
name: Yan, Han
name: Zhou, Xiaorong
name: Guo, Huixin
name: Leng, Zhaoguogang
name: Chen, Weiqi
name: Jia, Qiannan
name: Hu, Zexiang
name: Wu, Haojiang
name: Zhang, Xin
name: Jiang, Chengbao
name: Liu, Zhiqi
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Non-collinear antiferromagnetic materials have received dramatically increasing attention in the field of spintronics as their exotic topological features such as the Berry-curvature-induced anomalous Hall effect and possible magnetic Weyl states could be utilized in future topological antiferromagnetic spintronic devices. In this work, we report the successful integration of the antiferromagnetic metal Mn3Sn thin films onto ferroelectric oxide PMN-PT. By optimizing growth, we realized the large anomalous Hall effect with small switching magnetic fields of several tens mT fully comparable to those of bulk Mn3Sn single crystals, anisotropic magnetoresistance and negative parallel magnetoresistance in Mn3Sn thin films with antiferromagnetic order, which are similar to the signatures of the Weyl state in bulk Mn3Sn single crystals. More importantly, we found that the anomalous Hall effect in antiferromagnetic Mn3Sn thin films can be manipulated by electric fields applied onto the ferroelectric materials, thus demonstrating the feasibility of Mn3Sn-based topological spintronic devices operated in an ultralow power manner.
description: 25 pages, 10 figure. Accepted in Acta Materialia
Alternative Dark Energy Models: An Overview
Creators: name: Lima, J. A. S.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: A large number of recent observational data strongly suggest that we live in a flat, accelerating Universe composed of $\sim$ 1/3 of matter (baryonic + dark) and $\sim$ 2/3 of an exotic component with large negative pressure, usually named {\bf Dark Energy} or {\bf Quintessence}. The basic set of experiments includes: observations from SNe Ia, CMB anisotropies, large scale structure, X-ray data from galaxy clusters, age estimates of globular clusters and old high redshift galaxies (OHRG's). Such results seem to provide the remaining piece of information connecting the inflationary flatness prediction ($Ω_{\rm{T}} = 1$) with astronomical observations. Theoretically, they have also stimulated the current interest for more general models containing an extra component describing this unknown dark energy, and simultaneously accounting for the present accelerating stage of the Universe. An overlook in the literature shows that at least five dark energy candidates have been proposed in the context of general relativistic models. Since the cosmological constant and rolling scalar field models have already been extensively discussed, in this short review we focus our attention to the three remaining candidates, namely: a decaying vacuum energy density (or ${\bf Λ(t)}$ {\bf models}), the {\bf X-matter}, and the so-called {\bf Chaplygin-type gas}. A summary of their main results is given and some difficulties underlying the emerging dark energy paradigm are also briefly examined.
description: 11 pages, 4 figures, Invited talk at XXIII Brazilian National Meeting on Particles and Fields, Aguas de Lindoia, Sao Paulo, Brazil. To appear in Brazilian Journal of Physics (2004)
Cheumatopsyche addita
Creators: name: Oláh, János
name: Johanson, Kjell Arne
name: Barnard, Peter C.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Hydropsychidae
Cheumatopsyche
Cheumatopsyche addita

description: Cheumatopsyche addita (Navás, 1916)
 Hydropsychodes addita Navás, 1916: 88.
 Cheumatopsyche addita (Navás, 1916); Kimmins 1963: 130.
 Type locality: Russia (SE Siberia).
description: Published as part of Oláh, János, Johanson, Kjell Arne & Barnard, Peter C., 2008, Revision of the Oriental and Afrotropical species of Cheumatopsyche Wallengren (Hydropsychidae, Trichoptera), pp. 1-171 in Zootaxa 1738 on page 157
Characterizing the nuclease accessibility of DNA in human cells to map higher order structures of chromatin
Creators: name: Schwartz, Uwe
name: Németh, Attila
name: Diermeier, Sarah
name: Exler, Josef H.
name: Hansch, Stefan
name: Maldonado, Rodrigo
name: Heizinger, Leonhard
name: Merkl, Rainer
name: Längst, Gernot
Publisher: name: Universität Regensburg
Year: 2018
Subjects: subject: NUCLEOSOME ORGANIZATION; MICROCOCCAL NUCLEASE; CRYOELECTRON MICROSCOPY; READ ALIGNMENT; BETA-GLOBIN; IN-SITU; GENOME; TRANSCRIPTION; DOMAINS; FIBERS;
subject: 570 Biowissenschaften, Biologie

description: Packaging of DNA into chromatin regulates DNA accessibility and consequently all DNA-dependent processes. The nucleosome is the basic packaging unit of DNA forming arrays that are suggested, by biochemical studies, to fold hierarchically into ordered higher-order structures of chromatin. This organization has been recently questioned using microscopy techniques, proposing an irregular structure. To address the principles of chromatin organization, we applied an in situ differential MNase-seq strategy and analyzed in silico the results of complete and partial digestions of human chromatin. We investigated whether different levels of chromatin packaging exist in the cell. We assessed the accessibility of chromatin within distinct domains of kb to Mb genomic regions, performed statistical analyses and computer modelling. We found no difference in MNase accessibility, suggesting no difference in fiber folding between domains of euchromatin and heterochromatin or between other sequence and epigenomic features of chromatin. Thus, our data suggests the absence of differentially organized domains of higher-order structures of chromatin. Moreover, we identified only local structural changes, with individual hyper-accessible nucleosomes surrounding regulatory elements, such as enhancers and transcription start sites. The regulatory sites per se are occupied with structurally altered nucleosomes, exhibiting increased MNase sensitivity. Our findings provide biochemical evidence that supports an irregular model of large-scale chromatin organization.
The Statistical Significance of the Low CMB Mulitipoles
Creators: name: Efstathiou, G.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The Wilkinson Microwave Anisotropy Probe (WMAP) has measured lower amplitudes for the temperature quadrupole and octopole anisotropies than expected in the best fitting (concordance) Lambda-dominated cold dark matter cosmology. Some authors have argued that this discrepancy may require new physics. Yet the statistical significance of this result is not clear. Some authors have applied frequentist arguments and claim that the discrepancy would occur by chance about 1 time in 700 if the concordance model is correct. Other authors have used Bayesian arguments to claim that the data show marginal evidence for new physics. I investigate these confusing and apparently conflicting claims using a frequentist analysis and a simplified Bayesian analysis. I conclude that the WMAP results are consistent with the concordance Lambda CDM model.
description: 6 pages, Latex, 3 figs. Resubmission matches published version
Analytical investigation of ternary mixture of phenylephrine hydrochloride, dimetindene maleate and benzalkonium chloride using validated stability indicating HPLC-DAD method
Creators: name: Abdelhamid, Ahmed G.
name: El-Kafrawy, Dina S.
name: Magdi M. Abdel-Khalek
name: Belal, Tarek S.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: A stability-indicating high performance liquid chromatography method with diode array detection (HPLC-DAD) was developed and validated for simultaneous determination of phenylephrine hydrochloride (PHR), dimetindene maleate (DMD) and benzalkonium chloride (BZM) in nasal drops and gel dosage forms. Effective liquid chromatographic separation was accomplished by employing Venusil XBP Cyano column (4.6 × 250 mm, 5 µm particle size) with gradient elution of the mobile phase consisting of buffer solution of potassium dihydrogen phosphate (0.025 M) and sodium 1-butane sulfonate (SBS) (0.025 M) (adjusted to pH 6.0) and acetonitrile. Peak areas of PHR, DMD and BZM at 271, 256 and 206 nm, respectively were measured and correlated to their concentrations. Peaks of PHR and DMD eluted at retention times 3.76 and 9.06 min, respectively, while BZM eluted as a couple of peaks at 11.88 and 12.51 min. The proposed HPLC procedure was carefully validated in terms of system suitability, linearity, ranges, precision, accuracy, specificity, robustness, detection and quantification limits. The linearity range for both PHR and BZM was 10–400 μg/mL and DMD was 5–300 μg/mL with correlation coefficients >0.9999. The studied compounds were subjected to stress conditions of neutral, acidic and alkaline hydrolysis, oxidation and thermal degradation. Good resolution of the three compounds from their forced degradation products proves specificity and stability-indicating merits of the proposed method. In addition, resolution of the three drugs under investigation from some pharmaceutical compounds of different medicinal categories showed the high specificity of the described method.
Compatibility investigation for a new antituberculotic fixed dose combination with an adequate drug delivery
Creators: name: Petruševska, Valentina
name: Lasić, Kornelija
name: Mornar, Ana
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Computational Biology

description: The compatibility of formulation components is crucial for safe and high-quality medicines. To detect the potential for incompatibility and to assess formulation stability, it is beneficial to conduct a compatibility study during the drug development phase. The therapy of tuberculosis normally consists of two or more medicines taken together. Consequently, different antituberculotic fixed-dose combination (FDC) formulations have been developed. Isoniazid is first-line medicine and present in several FDCs. Low bioavailability due to the active substances’ incompatibility in acidic medium was reported for some of these FDC forms. Rifabutin, also a first-line antituberculotic, is available in the market as a single component formulation. This study presents compatibility testing of these two active substances for a new FDC and evaluates the impact of the most common solid dosage forms’ excipients on the stability of two active substances. The potential for interaction between the formulation components was analyzed by the UHPLC method. One degradation product and one interaction product were observed and further characterized by high-resolution mass spectrometry. Still, significant degradation of two active substances, such as reported in marketed FDC formulations was not detected for this combination. The stability and drug delivery of the proposed combination were confirmed by the dissolution test in acidic medium.
Cheumatopsyche bimaculata
Creators: name: Oláh, János
name: Johanson, Kjell Arne
name: Barnard, Peter C.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Hydropsychidae
Cheumatopsyche
Cheumatopsyche bimaculata

description: Cheumatopsyche bimaculata (Ulmer, 1930)
Fig. 213
 Hydropsychodes bimaculata Ulmer, 1930a: 491.
 Cheumatopsyche bimaculata (Ulmer, 1930); Mosely 1939: 27.
 Type locality: Ethiopia.
 Remarks: This species was described from female material. According to the forewing pattern it is a distinct species, but it is impossible to place it in species groups without knowing the male genital structures.
description: Published as part of Oláh, János, Johanson, Kjell Arne & Barnard, Peter C., 2008, Revision of the Oriental and Afrotropical species of Cheumatopsyche Wallengren (Hydropsychidae, Trichoptera), pp. 1-171 in Zootaxa 1738 on pages 157-158
On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx
Creators: name: Ochs, Matthias
name: Hegermann, Jan
name: Lopez-Rodriguez, Elena
name: Timm, Sara
name: Nouailles, Geraldine
name: Matuszak, Jasmin
name: Simmons, Szandor
name: Witzenrath, Martin
name: Kuebler, Wolfgang M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: lung
subject: alveoli
subject: air-blood barrier
subject: epithelium
subject: air-liquid interface
subject: alveolar lining layer
subject: glycocalyx
subject: surfactant
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Gas exchange in the lung takes place via the air-blood barrier in the septal walls of alveoli. The tissue elements that oxygen molecules have to cross are the alveolar epithelium, the interstitium and the capillary endothelium. The epithelium that lines the alveolar surface is covered by a thin and continuous liquid lining layer. Pulmonary surfactant acts at this air-liquid interface. By virtue of its biophysical and immunomodulatory functions, surfactant keeps alveoli open, dry and clean. What needs to be added to this picture is the glycocalyx of the alveolar epithelium. Here, we briefly review what is known about this glycocalyx and how it can be visualized using electron microscopy. The application of colloidal thorium dioxide as a staining agent reveals differences in the staining pattern between type I and type II alveolar epithelial cells and shows close associations of the glycocalyx with intraalveolar surfactant subtypes such as tubular myelin. These morphological findings indicate that specific spatial interactions between components of the surfactant system and those of the alveolar epithelial glycocalyx exist which may contribute to the maintenance of alveolar homeostasis, in particular to alveolar micromechanics, to the functional integrity of the air-blood barrier, to the regulation of the thickness and viscosity of the alveolar lining layer, and to the defence against inhaled pathogens. Exploring the alveolar epithelial glycocalyx in conjunction with the surfactant system opens novel physiological perspectives of potential clinical relevance for future research.