cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Studies of a Digital SiPM and MAPS Prototypes as Key Technologies for Future High-Energy Physics Experiments
Creators: name: Vignola, Gianpiero
Publisher: name: Universitäts- und Landesbibliothek Bonn
Year: 2025
Subjects: subject: SiPM
subject: MAPS
subject: CMOS
subject: Monolithic
subject: HEP
subject: ddc:530

description: Digital Silicon Photomultipliers (dSiPMs) and Monolithic Active Pixel Sensors (MAPS) are emerging technologies, fabricated using commercial Complementary Metal-Oxide-Semiconductor (CMOS) processes. These detectors have the potential to become key components in High-Energy Physics (HEP), with the ability to meet the demanding requirements of future experiments.
 The first part of the thesis analyzes the DESY dSiPM prototype as an example of the technology potential. Extensive laboratory characterizations confirm the functionality of the sensor and of all integrated CMOS circuitry. Sensor calibrations ensure stable and controlled operation enabling the study of prototype performance by offering an in-depth understanding of the sensor’s capabilities. The performance of the prototype in Minimum Ionising Particles (MIP) detection is evaluated through beam tests at the DESY II test-beam facility. The measurements aim to establish the potential use of this technology in 4D-Tracking of charged particles. The bare DESY dSiPM in MIP detection shows a spatial resolution of 20 µm, a time resolution of 50 ps with an efficiency of about 30 %, limited by the fill-factor characteristic of the technology. A novel detector-concept is therefore introduced that combines dSiPM with thin Cerium-doped Lutetium Yttrium Orthosilicate (LYSO(Ce)) radiators to overcome these efficiency limitations. This approach improves detection efficiency over 99 %, and enables better discrimination of signal events. The results presented support the potential use of dSiPM in MIPs 4D-tracking applications.
 The second part of this thesis focuses on MAPS technology, analyzing two prototypes developed using a 65 nm CMOS process. The first sensor, DESY Chip V1, is designed to verify the performance of a fast Charge Sensitive Amplifier (CSA), characterized in laboratory and test-beam. The studies confirm the functionality of the circuits while highlighting some limitations that contributed to design improvements in later versions. Several Analog Pixel Test Structure (APTS) prototypes are also studied in collaboration with CERN and the ALICE IT3 group. The operational parameters of the sensors are optimized and charge calibrations are performed. The study of the performance in MIP detection of an APTS prototype with a pixel pitch of 15 µm demonstrates spatial resolutions of less than 3 µm and detection efficiencies higher than 99 % with low noise occupancy in a wide operational window. The results presented support the potential of MAPS technology in meeting the stringent requirements of future experiments, particularly for vertex detectors in future lepton colliders.
A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila.
Creators: name: Webb, Rebecca L.
name: Zhou, Meng-Ning
name: McCartney, Brooke M.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The rearrangement of cytoskeletal elements is essential for many cellular processes. The tumor suppressor Adenomatous polyposis coli (APC) affects the function of microtubules and actin, but the mechanisms by which it does so are not well understood. Here we report that Drosophila syncytial embryos null for Apc2 display defects in the formation and extension of pseudocleavage furrows, which are cortical actin structures important for mitotic fidelity in early embryos. Furthermore, we show that the formin Diaphanous (DIA) functions with APC2 in this process. Colocalization of APC2 and DIA peaks during furrow extension, and localization of APC2 to furrows is DIA-dependent. Furthermore, APC2 binds DIA directly through a region of APC2 not previously shown to interact with DIA-related formins. Consistent with these results, reduction of dia enhances actin defects in Apc2 mutant embryos. Thus, an APC2-DIA complex appears crucial for actin furrow extension in the syncytial embryo. Interestingly, EB1, a microtubule +TIP and reported partner of vertebrate APC and DIA1, may not function with APC2 and DIA in furrow extension. Finally, whereas DIA-related formins are activated by Rho family GTPases, our data suggest that the APC2-DIA complex might be independent of RHOGEF2 and RHO1. Furthermore, although microtubules play a role in furrow extension, our analysis suggests that APC2 and DIA function in a novel complex that affects actin directly, rather than through an effect on microtubules.
Angular power spectrum analysis on current and future neutrino data
Creators: name: Dekker, Ariane
name: Shin'Ichiro Ando
name: Chianese, Marco
Publisher: name: Zenodo
Year: 2020

description: To constrain the contribution of source populations to the observed neutrino sky, we consider isotropic and anisotropic components of the diffuse neutrino data. We simulate through-going muon neutrino events by applying statistical distributions for the fluxes of extra-galactic sources and investigate the sensitivities of current (IceCube) and future (IceCube-Gen2 and KM3NeT) experiments. The angular power spectrum is a powerful probe to assess the angular characteristics of neutrino data and applying this analysis we are already constraining rare and bright sources with current IceCube data. In addition, we investigate the decay and annihilation of heavy dark matter as a potential neutrino source, as suggested by the observed excess in the High-Energy Starting Event dataset. We apply our angular power spectrum analysis to this HESE data for different channels, allowing us to interpret the observed neutrino sky and perform a sensitivity forecast.
Sufficient conditions for the additivity of stall forces generated by multiple filaments or motors
Creators: name: Bameta, Tripti
name: Das, Dipjyoti
name: Das, Dibyendu
name: Padinhateeri, Ranjith
name: Inamdar, Mandar M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: Subcellular Processes (q-bio.SC)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Molecular motors and cytoskeletal filaments work collectively most of the time under opposing forces. This opposing force may be due to cargo carried by motors or resistance coming from the cell membrane pressing against the cytoskeletal filaments. Some recent studies have shown that the collective maximum force (stall force) generated by multiple cytoskeletal filaments or molecular motors may not always be just a simple sum of the stall forces of the individual filaments or motors. To understand this excess or deficit in the collective force, we study a broad class of models of both cytoskeletal filaments and molecular motors. We argue that the stall force generated by a group of filaments or motors is additive, that is, the stall force of $N$ number of filaments (motors) is $N$ times the stall force of one filament (motor), when the system is in equilibrium at stall. Conversely, we show that this additive property typically does not hold true when the system is not at equilibrium at stall. We thus present a novel and unified understanding of the existing models exhibiting such non-addivity, and generalise our arguments by developing new models that demonstrate this phenomena. We also propose a quantity similar to thermodynamic efficiency to easily predict this deviation from stall-force additivity for filament and motor collectives.
description: 14 pages, 7 figures
NSI effects in next-generation neutrino experiments
Creators: name: Martinez-Miravé, Pablo
name: Tórtola, Mariam
name: Sedgwick, Susana Molina
Publisher: name: Zenodo
Year: 2020

description: Non-standard interactions (NSI) of neutrinos in matter have long been proposed as a way to quantify new physics in the neutrino sector beyond mass generation. Including these effects in the oscillation framework can lead to large differences in the interpretation of experimental data with respect to Standard Model (SM) weak interactions alone, causing degeneracies in measurements of the solar mixing angle, the CP-violating phase 𝛿, and the mass hierarchy, among others. By comparing the sensitivities of different experimental setups from current and future neutrino experiments, with a focus on measurements of solar and reactor neutrino oscillation parameters, it may be possible to establish whether these degeneracies can be resolved by the next generation of neutrino experiments, namely JUNO and Hyper-Kamiokande.
Photometry of Type II Supernova SN 2023ixf with a Worldwide Citizen Science Network
Creators: name: Sgro, Lauren A.
name: Esposito, Thomas M.
name: Blaclard, Guillaume
name: Gomez, Sebastian
name: Marchis, Franck
name: Filippenko, Alexei V.
name: Peluso, Daniel O'Conner
name: Lawrence, Stephen S.
name: Verveen, Aad
name: Wagner, Andreas
name: Nardi, Anouchka
name: Wiart, Barbara
name: Mirwald, Benjamin
name: Christensen, Bill
name: Eramia, Bob
name: Parker, Bruce
name: Guillet, Bruno
name: Kim, Byungki
name: Logan, Chelsey A.
name: Kyba, Christopher C. M.
name: Toulmin, Christopher
name: Vantaggiato, Claudio G.
name: Adhis, Dana
name: Gary, Dave
name: Goodey, Dave
name: Dickinson, David
name: Koster, David
name: Martin, Davy
name: Bonilla, Eliud
name: Chung, Enner
name: Miny, Eric
name: Mortecrette, Fabrice
name: Saibi, Fadi
name: Gagnon, Francois O.
name: Simard, François
name: Vacon, Gary
name: Simard, Georges
name: Dreise, Gerrit
name: Funakoshi, Hiromi
name: Vacon, Janet
name: Yaniz, James
name: Tarnec, Jean-Charles Le
name: Laugier, Jean-Marie
name: Siders, Jennifer L. W.
name: Sweitzer, Jim
name: Dvoracek, Jiri
name: Archer, John
name: Deitz, John
name: Bradley, John K.
name: Fukui, Keiichi
name: Sibbernsen, Kendra
name: Borrot, Kevin
name: Cross, Kevin
name: Heider, Kevin
name: Yamaguchi, Koichi
name: Hirsch, Lea A.
name: Leroux, Liouba
name: Billiani, Mario
name: Lorber, Markus
name: Smallen, Martin J.
name: Shimizu, Masao
name: Nishimura, Masayoshi
name: Ryno, Matthew
name: Cunningham, Michael
name: Gagnon, Michael
name: Primm, Michael
name: Rushton, Michael
name: Sibbernsen, Michael
name: Mitchell, Mike
name: Yoblonsky, Neil
name: Leroux, Niniane
name: Clerget, Olivier
name: Stojanović, Ozren
name: Unique, Patrice
name: Huth, Patrick
name: Ang, Raymund John
name: Santoni, Regis
name: Foster, Robert
name: Poggiali, Roberto
name: Xu, Ruyi
name: Kukita, Ryuichi
name: Šćepanović, Sanja
name: Saibi, Sophie
name: Will, Stefan
name: Latour, Stephan
name: Haythornthwaite, Stephen
name: Cadieux, Sylvain
name: Müller, Thoralf
name: Chung, Tze Yang
name: Watanabe, Yoshiya
name: Arnaud, Yvan
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present highly sampled photometry of the supernova (SN) 2023ixf, a Type II SN in M101, beginning 2 days before its first known detection. To gather these data, we enlisted the global Unistellar Network of citizen scientists. These 252 observations from 115 telescopes show the SN's rising brightness associated with shock emergence followed by gradual decay. We measure a peak $M_{V}$ = -18.18 $\pm$ 0.09 mag at 2023-05-25 21:37 UTC in agreement with previously published analyses.
description: 4 pages, 1 figure
A sensor of protein O-glycosylation based on sequential processing in the Golgi apparatus.
Creators: name: Bachert, Collin
name: Linstedt, Adam
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Protein O-glycosylation is important in numerous processes including the regulation of proteolytic processing sites by O-glycan masking in select newly synthesized proteins. To investigate O-glycan-mediated masking using an assay amenable to large-scale screens, we generated a fluorescent biosensor with an O-glycosylation site situated to mask a furin cleavage site. The sensor is activated when O-glycosylation fails to occur because furin cleavage releases a blocking domain allowing dye binding to a fluorogen activating protein. Thus, by design, glycosylation should block furin from activating the sensor only if it occurs first, which is predicted by the conventional view of Golgi organization. Indeed, and in contrast to the recently proposed rapid partitioning model, the sensor was non-fluorescent under normal conditions but became fluorescent when the Golgi complex was decompartmentalized. To test the utility of the sensor as a screening tool, cells expressing the sensor were exposed to a known inhibitor of O-glycosylation extension or siRNAs targeting factors known to alter glycosylation efficiency. These conditions activated the sensor substantiating its potential in identifying new inhibitors and cellular factors related to protein O-glycosylation. In summary, these findings confirm sequential processing in the Golgi, establish a new tool for studying the regulation of proteolytic processing by O-glycosylation, and demonstrate the sensor's potential usefulness for future screening projects.
Statistical methods for the new data release of GERDA
Creators: name: Agostini, Matteo
name: Caldwell, Allen
name: Lolian Shtembari
name: Schulz, Oliver
Publisher: name: Zenodo
Year: 2020

description: The GERDA experiment investigates lepton-number violation and whether neutrinos have a Majorana nature by searching for a rare nuclear transition called neutrinoless double beta decay (0vbb). The statistical challenges that arise in the search for rare-processes: evaluating the discovery power, the limit setting power on the signal rate and the goodness of fit of the background for models with data sets consisting of a small number of events are discussed. The topics selected include the systematic variations in the results due to the choice of fit models. This is investigated through Bayesian Hierarchical modelling. Order statistics and the Bayes factor are used as tools to study the background goodness of fit and the signal discovery power.
Activation of the skeletogenic gene regulatory network in the early sea urchin embryo.
Creators: name: Sharma, Tara
name: Ettensohn, Charles A.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The gene regulatory network (GRN) that underlies the development of the embryonic skeleton in sea urchins is an important model for understanding the architecture and evolution of developmental GRNs. The initial deployment of the network is thought to be regulated by a derepression mechanism, which is mediated by the products of the pmar1 and hesC genes. Here, we show that the activation of the skeletogenic network occurs by a mechanism that is distinct from the transcriptional repression of hesC. By means of quantitative, fluorescent whole-mount in situ hybridization, we find that two pivotal early genes in the network, alx1 and delta, are activated in prospective skeletogenic cells prior to the downregulation of hesC expression. An analysis of the upstream regulation of alx1 shows that this gene is regulated by MAPK signaling and by the transcription factor Ets1; however, these inputs influence only the maintenance of alx1 expression and not its activation, which occurs by a distinct mechanism. By altering normal cleavage patterns, we show that the zygotic activation of alx1 and delta, but not that of pmar1, is dependent upon the unequal division of vegetal blastomeres. Based on these findings, we conclude that the widely accepted double-repression model is insufficient to account for the localized activation of the skeletogenic GRN. We postulate the existence of additional, unidentified repressors that are controlled by pmar1, and propose that the ability of pmar1 to derepress alx1 and delta is regulated by the unequal division of vegetal blastomeres.
Geometric Adaptive Tracking Control of a Quadrotor UAV on SE(3) for Agile Maneuvers
Creators: name: Goodarzi, Farhad A.
name: Lee, Daewon
name: Lee, Taeyoung
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: This paper presents nonlinear tracking control systems for a quadrotor unmanned aerial vehicle under the influence of uncertainties. Assuming that there exist unstructured disturbances in the translational dynamics and the attitude dynamics, a geometric nonlinear adaptive controller is developed directly on the special Euclidean group. In particular, a new form of an adaptive control term is proposed to guarantee stability while compensating the effects of uncertainties in quadrotor dynamics. A rigorous mathematical stability proof is given. The desirable features are illustrated by numerical example and experimental results of aggressive maneuvers.
description: arXiv admin note: substantial text overlap with arXiv:1304.6765, arXiv:1109.4457
Hardware Development for the Radio Neutrino Observatory in Greenland
Creators: name: Smith, Daniel
Publisher: name: Zenodo
Year: 2020

description: The Radio Neutrino Observatory in Greenland (RNO-G) is designed to make the first observations of ultra-high energy neutrinos at energies above 100 PeV via the detection of Askaryan radiation and serve as a technology pathfinder for IceCube-Gen2. The experiment will be composed of 35 autonomous stations deployed over a 5 x 6 km grid near to NSF's Summit Station in Greenland. The electronics chain of each station is optimized for sensitivity and low power, incorporating deep and surface 150 - 600 MHz RF antennas, low-noise amplifiers, custom RF-over-fiber systems, and an FPGA-based phased array trigger. Each station will operate at 25 W, allowing for a live time of ~70% from a solar power system. I will also present on the DAQ and communication systems as well as plans for the first seasons of deployment in Summer 2020 and Summer 2021.
A report of the Curriculum Task Force of the ISCB Education Committee.
Creators: name: Welch, Lonnie R
name: Schwartz, Russell
name: Lewitter, Fran
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The International Society for Computational Biology (ISCB) Education Committee (EduComm) promotes worldwide education and training in computational biology and bioinformatics and serves as a resource and advisor to organizations interested in developing educational programs.
The topic of curricula for bioinformatics programs has long been of interest to ISCB and EduComm. Dr. Russ Altman, a founding board member and past president of ISCB, has been associated with one of the first bioinformatics degree programs (at Stanford University) and wrote an article on this topic [1]. Dr. Shoba Ranganathan, as chair of EduComm a decade ago, began organizing a yearly Workshop on Education in Bioinformatics (WEB) at Intelligent Systems for Molecular Biology (ISMB) meetings that generated exchange of information and many productive discussions. Curriculum development was one aspect of bioinformatics education covered in these sessions [2].
Low-Latency Algorithm for Multi-messenger Astrophysics (LLAMA) search for common sources of gravitational waves and high-energy neutrinos
Creators: name: Doga Veske
name: Marka, Szabolcs
name: Countryman, Stefan
name: Marka, Zsuzsa
name: Bartos, Imre
name: Yasmeen Asali
Publisher: name: Zenodo
Year: 2020

description: For more than a decade, searches for common sources of gravitational-waves (GWs) and astrophysical neutrinos have returned null results. With the open public alerts of LIGO-Virgo during their third observing run O3 in 2019-2020, search for high energy neutrinos continued in realtime with IceCube. Here, we describe our analysis with Low-Latency Algorithm for Multi-messenger Astrophysics (LLAMA) which incorporates a Bayesian formalism with astrophysical priors to use the distance information from the 3D localization of GW detections for higher statistical power. Finally, we summarize our results during O3.
THE IMPACT OF ARTIFICIAL INTELLIGENCE IN HRM: ASSESSING RECRUITMENT, PERFORMANCE MANAGEMENT, AND EMPLOYEE EXPERIENCE
Creators: name: ANURADHA REKHADI
name: UMA DEVI M
Publisher: name: Zenodo
Year: 2023
Subjects: Artificial Intelligence, HRM, Recruitment, Performance Management, Employee Satisfaction

description: Abstract
The infusion of Artificial Intelligence (AI) into Human Resources Management (HRM) practices has brought about a paradigm shift in recruitment, performance management, and employee experience. AI-driven tools have expedited candidate selection through data-driven insights, reducing biases and fostering inclusivity. Real-time performance tracking facilitated by AI algorithms has enabled continuous feedback and personalized development plans, nurturing employee growth and engagement. This paper presents a comprehensive analysis of the transformative impact of Artificial Intelligence (AI) on various aspects of Human Resources Management (HRM), focusing specifically on recruitment, performance management, and employee experience. The research methodology employed in this study consists of a mixed-methods approach. Qualitative data was gathered through in-depth interviews with HR professionals from diverse industries to understand their perspectives on AI adoption and its effects on HRM functions. Additionally, quantitative analysis was conducted on organizational data to assess the tangible outcomes of AI implementation in terms of recruitment efficiency, performance enhancement, and overall employee satisfaction. The findings of the study elucidate that AI-driven recruitment tools have significantly expedited candidate selection processes by automating resume screening and matching candidates to job profiles. This has not only reduced human bias but also led to more accurate and informed hiring decisions. In the domain of performance management, the real-time tracking capabilities of AI algorithms have enabled continuous monitoring, facilitating timely feedback and personalized development plans. The study's implications offer actionable insights for organizations seeking to leverage AI in HR, guiding informed integration strategies, evidence-based decision-making, and the cultivation of an employee-centric approach, while emphasizing ethical considerations and fostering avenues for future research and innovation.
Profit Maximization for Geographical Dispersed Green Data Centers
Creators: name: Kiani, Abbas
name: Ansari, Nirwan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: This paper aims at maximizing the profit associated with running geographically dispersed green data centers, which offer multiple classes of service. To this end, we formulate an optimization framework which relies on the accuracy of the G/D/1 queue in characterizing the workload distribution, and taps on the merits of the workload decomposition into green and brown workload served by green and brown energy resources. Moreover, we take into account of not only the Service Level Agreements (SLAs) between the data centers and clients but also different deregulated electricity markets of data centers located at different regions. We prove the convexity of our optimization problem and the performance of the proposed workload distribution strategy is evaluated via simulations.
Supersymetric laser arrays
Creators: name: El-Ganainy, Ramy
name: Ge, Li
name: Khajavikhan, Mercedeh
name: Christodoulides, Demetrios
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We introduce the concept of supersymmetric laser arrays that consists of a main optical lattice and its superpartner structure, and we investigate the onset of their lasing oscillations. Due to the coupling of the two constituent lattices, their degenerate optical modes form doublets, while the extra mode associated with unbroken supersymmetry forms a singlet state. Singlet lasing can be achieved for a wide range of design parameters either by introducing stronger loss in the partner lattice or by pumping only the main array. Our findings suggest the possibility of building single-mode, high-power laser arrays and are also important for understanding light transport dynamics in multimode Parity-Time symmetric photonic structures.
Adult neurogenesis and specific replacement of interneuron subtypes in the mouse main olfactory bulb.
Creators: name: Bagley, Joshua
name: Larocca, Gregory
name: Jimenez, Daniel A.
name: Urban, Nathan
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: BACKGROUND: New neurons are generated in the adult brain from stem cells found in the subventricular zone (SVZ). These cells proliferate in the SVZ, generating neuroblasts which then migrate to the main olfactory bulb (MOB), ending their migration in the glomerular layer (GLL) and the granule cell layer (GCL) of the MOB. Neuronal populations in these layers undergo turnover throughout life, but whether all neuronal subtypes found in these areas are replaced and when neurons begin to express subtype-specific markers is not known.
RESULTS: Here we use BrdU injections and immunohistochemistry against (calretinin, calbindin, N-copein, tyrosine hydroxylase and GABA) and show that adult-generated neurons express markers of all major subtypes of neurons in the GLL and GCL. Moreover, the fractions of new neurons that express subtype-specific markers at 40 and 75 days post BrdU injection are very similar to the fractions of all neurons expressing these markers. We also show that many neurons in the glomerular layer do not express NeuN, but are readily and specifically labeled by the fluorescent nissl stain Neurotrace.
CONCLUSION: The expression of neuronal subtype-specific markers by new neurons in the GLL and GCL changes rapidly during the period from 14-40 days after BrdU injection before reaching adult levels. This period may represent a critical window for cell fate specification similar to that observed for neuronal survival.
Discontinuous phase transition in an open-ended Naming Game
Creators: name: Crokidakis, Nuno
name: Brigatti, Edgardo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: In this work we study on a 2-dimensional square lattice a recent version of the Naming Game, an agent-based model used for describing the emergence of linguistic structures. The system is open-ended and agents can invent new words all along the evolution of the game, picking them up from a pool characterised by a Gaussian distribution with standard deviation $σ$. The model displays a nonequilibrium phase transition at a critical point $σ_{c}\approx 25.6$, which separates an absorbing consensus state from an active fragmented state where agents continuously exchange different words. The finite-size scaling analysis of our simulations strongly suggests that the phase transition is discontinuous.
description: 13 pages, 6 figures, to appear in JSTAT
title: Left behind : reflections of residential care home managers when children leave
Creators: name: Bhagat, Yesha
name: O'Reilly, Barbara
Publisher: name: Strathprints - University of Strathclyde
Year: 2021

description: A case study of a children's therapeutic residential care provider consisting of five homes in England was carried out to consider the feelings and reflections of the managers on children leaving the home. This is an unexplored perspective/ subject which considers the significant and emotional transition of leaving care. The reflections in this case study can be used to improve practice for social care providers and give insights into a niche area of work. To explore this topic, a focus group was carried out with four residential home managers and two psychotherapists who work at the same care provider. It was found that the subject of leavers was not much reflected on and it was agreed that it needed to be to improve practice, as well as processing certain unconscious feelings around the child. Failure was a prominent feeling potentially derived from the pressure of ending cycles of failure for the children as well as unconscious projections held by the managers. There were also found to be certain issues around terminology, such as 'planned' and 'unplanned', used in this area of work which holds particular connotations. Lastly, it was found that relationships with local authorities were significant for ensuring healthy transitions.
Estimating perceived image complexity with Multiscale Entropy
Creators: name: Wilder, John
name: Zhou, Elizabeth Y
name: Bernhardt-Walther, Dirk
name: Damiano, Claudia
Publisher: name: Open Science Framework
Year: 2023

description: The perceived complexity of an image is an image feature that is related to aesthetic pleasure ratings and other subjective visual perceptions. In this study we develop a new computational measure which is largely based on multiscale entropy (MSE) introduced by Costa, Goldberger, and Peng (2002).
Long-lived resonances at mirrors
Creators: name: Queisser, Friedemann
name: Unruh, William G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Motivated by realistic scattering processes of composite systems, we study the dynamics of a two-particle bound system which is scattered at a mirror. The physics of the scattering process will be discussed in the cases when only one particle interacts directly with the mirror and when both particles are scattered directly. It is shown that the coherence between the transmitted and the reflected wave-packet becomes reduced due to the scattering process. When both particles interact directly with the mirror, the system exhibits long-lived resonances. The results should be of interest for interference experiments with composite systems.
description: 5 pages, 11 figures
From infinitesimal symmetries to deformed symmetries of Lax-type equations
Creators: name: Magnot, Jean-Pierre
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: Differential Geometry (math.DG)
subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 22E65, 22E66, 58B25, 70G65

description: Using the procedure initiated in \cite{Ma2013}, we deform Lax-type equations though a scaling of the time parameter. This gives an equivalent (deformed) equation which is integrable in terms of power series of the scaling parameter. We then describe a regular Frölicher Lie group of symmetries of this deformed equation
description: arXiv admin note: substantial text overlap with arXiv:1402.5629
An extensive circuitry for cell wall regulation in Candida albicans.
Creators: name: Blankenship, Jill R.
name: Saranna  Fanning
name: Hamaker, Jessica J
name: Mitchell, Aaron
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Protein kinases play key roles in signaling and response to changes in the external environment. The ability of Candida albicans to quickly sense and respond to changes in its environment is key to its survival in the human host. Our guiding hypothesis was that creating and screening a set of protein kinase mutant strains would reveal signaling pathways that mediate stress response in C. albicans. A library of protein kinase mutant strains was created and screened for sensitivity to a variety of stresses. For the majority of stresses tested, stress response was largely conserved between C. albicans, Saccharomyces cerevisiae, and Schizosaccharomyces pombe. However, we identified eight protein kinases whose roles in cell wall regulation (CWR) were not expected from functions of their orthologs in the model fungi Saccharomyces cerevisiae and Schizosaccharomyces pombe. Analysis of the conserved roles of these protein kinases indicates that establishment of cell polarity is critical for CWR. In addition, we found that septins, crucial to budding, are both important for surviving and are mislocalized by cell wall stress. Our study shows an expanded role for protein kinase signaling in C. albicans cell wall integrity. Our studies suggest that in some cases, this expansion represents a greater importance for certain pathways in cell wall biogenesis. In other cases, it appears that signaling pathways have been rewired for a cell wall integrity response.
Bayesian analysis of Project 8's sensitivity to the neutrino mass scale and ordering
Creators: name: Weiss, Talia
Publisher: name: Zenodo
Year: 2020

description: Project 8 aims to determine the absolute neutrino mass scale from a tritium beta spectrum using Cyclotron Radiation Emission Spectroscopy (CRES). Bayesian analysis is suited for direct mass measurements because it incorporates non-Gaussian features—like the mass's physical bound at zero—without invoking approximate interval building techniques. Bayesian methods also separate inference from result-reporting, revealing how both affect accuracy. Project 8 devised a new Bayesian beta spectrum model and applied it to the first CRES tritium spectrum. We analyze pseudo-spectra with this model, then observe how often the inferred mass scale and hierarchy agree with "truths." 90% credible intervals contain the true mass in $>$90% of analyses, validating our model. For a design under consideration, we find Project 8 can achieve its goal of measuring $m_\beta$ within 40meV with $\sim$1 year of data. Masses $>$500meV can be measured within 90% intervals of width ≈5meV.
vIOLETA: Neutrino Interaction Observation with a Low Energy Threshold Array
Creators: name: D'Olivo, Juan Carlos
name: Bonifazi, Carla
name: Rodrigues, Dario
name: Moroni, Guillermo Fernandez
Publisher: name: Zenodo
Year: 2020

description: The large number of opportunities to study non-standard neutrinos interaction in the low energy range --below the inverse beta decay process-- along with the observation of the CEvNs interaction, have witnessed a growing interest during the last years. In this contest, we propose a short baseline reactor neutrino experiment to cover three orders of magnitude of unexplored energy range for neutrino interaction using 10 kg of Skipper-CCD detectors with an energy threshold of approximately 1 eV. We discuss constraints to the SM and also benchmark beyond SM. In particular, we claim that our prospective for the exposure time required for observing the CEvNs at a 90% of confidence level at one of the most powerful nuclear reactors available in Argentina is only 1.5 days.
Striped Ferronematic ground states in a spin-orbit coupled $S=1$ Bose gas
Creators: name: Natu, Stefan S.
name: Li, Xiaopeng
name: Cole, William S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We theoretically establish the mean-field phase diagram of a homogeneous spin-$1$, spin-orbit coupled Bose gas as a function of the spin-dependent interaction parameter, the Raman coupling strength and the quadratic Zeeman shift. We find that the interplay between spin-orbit coupling and spin-dependent interactions leads to the occurrence of ferromagnetic or ferronematic phases which also break translational symmetry. For weak Raman coupling, increasing attractive spin-dependent interactions (as in $^{87}$Rb or $^7$Li) induces a transition from a uniform to a stripe XY ferromagnet (with no nematic order). For repulsive spin-dependent interactions however (as in $^{23}$Na), we find a transition from an $XY$ spin spiral phase ($= 0$ and uniform total density) with uniaxial nematic order, to a biaxial ferronematic, where the total density, spin vector and nematic director oscillate in real space. We investigate the stability of these phases against the quadratic Zeeman effect, which generally tends to favor uniform phases with either ferromagnetic or nematic order but not both. We discuss the relevance of our results to ongoing experiments on spin-orbit coupled, spinor Bose gases.
description: 6 pages, 4 figures
Precise measurement of two-neutrino double beta decay half-life of $^{100}$Mo using enriched Li$_{2}$$^{100}$MoO$_{4}$ scintillating crystals
Creators: name: Singh, Vivek
Publisher: name: Zenodo
Year: 2020

description: We will present the most precise measurement of the two-neutrino double-beta decay of $^{100}$Mo using lithium molybdate scintillating low-temperature calorimeters. We used four highly radiopure and $^{100}$Mo-enriched crystals for the measurement. We developed the detectors under the purview of the CUPID-Mo experiment and operated them in the EDELWEISS-III low-background facility in the Modane underground laboratory. We rejected the contribution of $\alpha$ particles and reduced our background by simultaneously detecting the heat and light channel in the crystal. With a high selection efficiency ($\sim$ 96\%) and an exposure of 42.235 kg$\times$d, we measured the half-life to be T$^{2\nu}_{1/2}$ = [7.12$^{+0.18}_{-0.14}$ (stat.) $\pm$ 0.10 (syst.)] $\times$ 10$^{18}$ years. We will present an overview of experiment, analysis of the background model, and a discussion on the reported systematic errors.
Chemical Abundances and Dust in the Halo Planetary Nebula K648 in M15: Its Origin and Evolution based on an Analysis of Multiwavelength Data
Creators: name: Otsuka, Masaaki
name: Hyung, Siek
name: Tajitsu, Akito
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report an investigation of the extremely metal-poor and C-rich planetary nebula (PN) K648 in the globular cluster M15 using the UV to far-IR data obtained using the Subaru, HST, FUSE, Spitzer, and Herschel. We determined the nebular abundances of ten elements. The enhancement of F ([F/H]=+0.96) is comparable to that of the halo PN BoBn1. The central stellar abundances of seven elements are determined. The stellar C/O ratio is similar to the nebular C/O ratios from recombination line and from collisionally excited line (CEL) within error, and the stellar Ne/O ratio is also close to the nebular CEL Ne/O ratio. We found evidence of carbonaceous dust grains and molecules including Class B 6-9 um and 11.3 um polycyclic aromatic hydrocarbons and the broad 11 um feature. The profiles of these bands are similar to those of the C-rich halo PNe H4-1 and BoBn1. Based on the theoretical model, we determined the physical conditions of the gas and dust and their masses, i.e., 0.048 Msun and 4.95x10^{-7} Msun, respectively. The observed chemical abundances and gas mass are in good agreement with an asymptotic giant branch nucleosynthesis model prediction for stars with an initial 1.25 Msun plus a 2.0x10^{-3} Msun partial mixing zone (PMZ) and stars with an initial mass of 1.5 Msun without a PMZ. The core-mass of the central star is approximately 0.61-0.63 Msun. K648 is therefore likely to have evolved from a progenitor that experienced coalescence or tidal disruption during the early stages of evolution, and became a ~1.25-1.5 Msun blue straggler.
description: 23 pages, 14 Figures and 20 Tables, accepted for publication in the Astrophysical Journal Supplement Series
Decay widths of the spin-2 partners of the X(3872)
Creators: name: Albaladejo, M.
name: Guo, F. -K.
name: Hidalgo-Duque, C.
name: Nieves, J.
name: Valderrama, M. Pavon
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We consider the $X(3872)$ resonance as a $J^{PC}=1^{++}$ $D\bar D^*$ hadronic molecule. According to heavy quark spin symmetry, there will exist a partner with quantum numbers $2^{++}$, $X_{2}$, which would be a $D^*\bar D^*$ loosely bound state. The $X_{2}$ is expected to decay dominantly into $D\bar D$, $D\bar D^*$ and $\bar D D^*$ in $d$-wave. In this work, we calculate the decay widths of the $X_{2}$ resonance into the above channels, as well as those of its bottom partner, $X_{b2}$, the mass of which comes from assuming heavy flavor symmetry for the contact terms. We find partial widths of the $X_{2}$ and $X_{b2}$ of the order of a few MeV. Finally, we also study the radiative $X_2\to D\bar D^{*}γ$ and $X_{b2} \to \bar B B^{*}γ$ decays. These decay modes are more sensitive to the long-distance structure of the resonances and to the $D\bar D^{*}$ or $B\bar B^{*}$ final state interaction.
description: 46 pages, 11 figures
Detection of the secondary eclipse of WASP-10b in the Ks-band
Creators: name: Cruz, Patricia
name: Barrado, David
name: Lillo-Box, Jorge
name: Diaz, Marcos
name: Birkby, Jayne
name: López-Morales, Mercedes
name: Hodgkin, Simon
name: Fortney, Jonathan J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: WASP-10b, a non-inflated hot Jupiter, was discovered around a K-dwarf in a near circular orbit ($\sim $$0.06$). Since its discovery in 2009, different published parameters for this system have led to a discussion about the size, density, and eccentricity of this exoplanet. In order to test the hypothesis of a circular orbit for WASP-10b, we have observed its secondary eclipse in the Ks-band, where the contribution of planetary light is high enough to be detected from the ground. Observations were performed with the OMEGA2000 instrument at the 3.5-meter telescope at Calar Alto (Almería, Spain), in staring mode during 5.4 continuous hours, with the telescope defocused, monitoring the target during the expected secondary eclipse. A relative light curve was generated and corrected from systematic effects, using the Principal Component Analysis (PCA) technique. The final light curve was fitted using a transit model to find the eclipse depth and a possible phase shift. The best model obtained from the Markov Chain Monte Carlo analysis resulted in an eclipse depth of $ΔF$ of $0.137\%^{+0.013\%}_{-0.019\%}$ and a phase offset of $Δϕ$ of $-0.0028^{+0.0005}_{-0.0004}$. The eclipse phase offset derived from our modeling has systematic errors that were not taken into account and should not be considered as evidence of an eccentric orbit. The offset in phase obtained leads to a value for $|e\cosω|$ of $0.0044$. The derived eccentricity is too small to be of any significance.
description: 8 pages, 10 figures
title: From procedural child rights education to a relational child rights-based practice model
Creators: name: Collins, Tara
name: Gharabaghi, Kiaras
name: Caruana, Sheldon
name: Cherry, Shannon
name: Marcano-Henry, Richard
Publisher: name: Strathprints - University of Strathclyde
Year: 2021

description: Children's rights are often operationalised in administrative and procedural ways, particularly in child welfare and residential services contexts. In this article, a group of five authors representing academics and alumni from Ryerson University's Child & Youth Care programme who are also people from care present a dialogue process surrounding lived experiences of rights education processes while in care. The dialogue is complemented with a review of child rights education material used by child welfare agencies in Ontario, Canada as tools to explain rights to children and youth admitted into care. We conclude that a child rights-based practice model is necessary in which rights and daily life are fully integrated.
Analysis of dishevelled localization and function in the early sea urchin embryo.
Creators: name: Leonard, Jennifer D.
name: Ettensohn, Charles A.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Dishevelled (Dsh) is a key signaling molecule in the canonical Wnt pathway. Although the mechanism by which Dsh transduces a Wnt signal remains elusive, the subcellular localization of Dsh may be critical for its function. In the early sea urchin embryo, Dsh is concentrated in punctate structures within the cytoplasm of vegetal blastomeres. In these cells, Dsh stabilizes beta-catenin and causes it to accumulate in nuclei, resulting in the activation of transcriptional gene regulatory networks that drive mesoderm and endoderm formation. Here, we present a systematic mutational analysis of Lytechinus variegatus Dsh (LvDsh) that identifies motifs required for its vegetal cortical localization (VCL). In addition to a previously identified lipid-binding motif near the N-terminus of Dsh (Weitzel, H.E., Illies, M.R., Byrum, C.A., Xu, R., Wikramanayake, A.H., Ettensohn, C.A., 2004. Differential stability of beta-catenin along the animal-vegetal axis of the sea urchin embryo mediated by dishevelled. Development 131, 2947-56), we identify a short (21 amino acid) motif between the PDZ and DEP domains that is required for VCL. Phosphorylation of threonine residues in this region regulates both the targeting and stability of LvDsh. We also identify functional nuclear import and export signals within LvDsh. We provide additional evidence that LvDsh is active locally in the vegetal region of the embryo but is inactive in animal blastomeres and show that the inability of LvDsh to function in animal cells is not a consequence of impaired nuclear import. The DIX domain of LvDsh functions as a potent dominant negative when overexpressed (Weitzel, H.E., Illies, M.R., Byrum, C.A., Xu, R., Wikramanayake, A.H., Ettensohn, C.A., 2004. Differential stability of beta-catenin along the animal-vegetal axis of the sea urchin embryo mediated by dishevelled. Development 131, 2947-56). Here, we show that the dominant negative effect of DIX is dependent on a highly conserved, lipid-binding motif that includes residues K57 and E58. The dominant negative effect of DIX is not a consequence of blocking VCL or the nuclear import of LvDsh. We provide evidence that isolated DIX domains interact with full-length LvDsh in vivo. In addition, we show that the K57/E58 lipid-binding motif of DIX is essential for this interaction. We propose that binding of the isolated DIX domain to full-length Dsh may be facilitated by interactions with lipids, and that this interaction may inhibit signaling by a) preventing endogenous Dsh from interacting with Axin, or b) blocking the ability of Dsh to recruit other proteins, such as GBP/Frat1, to the beta-catenin degradation complex.
The effect of 2-day heat stress on the lipid composition of bovine milk and serum
Creators: name: Li, Cheng
name: Liu, Zhiqian
name: Bath, Carolyn
name: Marett, Leah C
name: Pryce, Jennie
name: Rochfort, Simone
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 300307
subject: Environmental studies in animal production
classificationCode: 3003
subject: Animal production

description: Milk and serum were collected from dairy cows before and during a 2-day heat challenge. The concentrations of free short-chain fatty acids (SCFAs), the fatty acid (FA) profile, and the abundance of the major species of phosphatidylcholine (PC), phosphatidylethanolamine (PE), and sphingomyelin (SM) were measured, and samples collected during heat exposure were compared with those collected prior to heat exposure. It was found that a 2-day heat challenge did not alter the global FA composition of milk fat nor the content of the major phospholipids. Although the concentration of SCFAs C3 and C4 and some lysophosphatidylcholine (LPC) species in milk was found to be associated with the forage type, neither of these lipid molecules can be used as an indicator of acute heat stress. While it is a positive finding that short-term heat stress has no detrimental effect on the FA composition or the nutritive quality of milk fat, this study highlights the complexity of validating a milk lipid biomarker for heat stress in dairy cows.