cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Boundary Functions for Ideals in Analytic Limit Algebras
Creators: name: Hopenwasser, Alan
Publisher: name: arXiv
Year: 1998
Subjects: subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 47D25

description: We develop a theory of boundary functions for ideals in trivially analytic subalgebras of simple AF C*-algebras with an injective 0-cocycle, a class which includes all full nest algebras. Boundary functions are maps from the spectrum of the diagonal of the analytic subalgebra to itself. The relation between boundary functions and ideal sets is explored and a description is given of meet and join irreducible boundary functions.
description: AMS-TeX; 23 pages; to appear Illinois J. Math
On Wiener index of graphs and their line graphs
Creators: name: Cohen, Nathann
name: Dimitrov, Darko
name: Krakovski, Roi
name: Škrekovski, Riste
name: Vukašinović, Vida
Publisher: name: Freie Universität Berlin
Year: 2009
Subjects: subject: Wiener index
subject: line graphs
subject: 000 Informatik, Informationswissenschaft, allgemeine Werke::000 Informatik, Wissen, Systeme::006 Spezielle Computerverfahren
subject: 500 Naturwissenschaften und Mathematik::510 Mathematik::510 Mathematik

description: The Wiener index of a graph G, denoted by W(G), is the sum of distances between all pairs of vertices in G. In this paper, we consider the relation between the Wiener index of a graph, G, and its line graph, L(G). We show that if G is of minimum degree at least two, then W(G) <= W(L(G)). We prove that for every non-negative integer g_0, there exists g>g_0, such that there are infinitely many graphs G of girth g, satisfying W(G) = W(L(G)). This partially answers a question raised by Dobrynin and Mel'nikov and encourages us to conjecture that the answer to a stronger form of their question is affirmative.
Spectral response of Cantor multilayers made of materials with negative refractive index
Creators: name: Gerardin, Jaline
name: Lakhtakia, Akhlesh
Publisher: name: arXiv
Year: 2002
Subjects: subject: Classical Physics (physics.class-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Whereas Cantor multilayers made of an isotropic dielectric-magnetic material with positive refractive index will show power-law characteristics, low-order Cantor multilayers made of materials with negative refractive index will not exhibit the power-law nature. A reason for this anomalous behavior is presented.
description: 10 pages, 2 figures
Additional file 3: of Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation
Creators: name: Costa, Elodie Da
name: Armaos, Gregory
name: McInnes, Gabrielle
name: Beaudry, Annie
name: Moquin-Beaudry, Gaël
name: Bertrand-Lehouillier, Virginie
name: Caron, Maxime
name: Richer, Chantal
name: St-Onge, Pascal
name: Johnson, Jeffrey
name: Nevan Krogan
name: Sai, Yuka
name: Downey, Michael
name: Moutih Rafei
name: Boileau, Meaghan
name: Eppert, Kolja
name: Flores-Díaz, Ema
name: Haman, André
name: Hoang, Trang
name: Sinnett, Daniel
name: Beauséjour, Christian
name: McGraw, Serge
name: Raynal, Noël
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Figure S2. Transcriptomic Analysis In MOLT-4 Cells Treated with Proscillaridin A (5 nM, 48h). A Heat map representing RPKM similarities between triplicates of untreated (U) and Proscillaridin A-treated (5 nM; 48h; T) MOLT-4 cells (n = 3). Red color corresponds to the highest similarity and yellow corresponds to the lowest similarity. B Proscillaridin A (5 nM, 48h) induced gene expression reprogramming of MOLT-4 cells. Volcano plots of gene expression changes in MOLT-4 cells in untreated versus treated samples. Black dots correspond to genes with P-value adjusted > 0.5. Grey dots correspond to genes with P-value adjusted < 0.5 but without significant fold change expression difference between untreated and treated cells (-0.5 < FC < 1). Downregulated genes with P-value adjusted < 0.5 and FC < -0.5 are shown in green. Upregulated genes with P-value adjusted < 0.5 and FC > 1 are shown in red. Numbers of downregulated and upregulated genes are shown on the graphs. C Metascape analysis of genes downregulated by proscillaridin A treatment (5 nM; 48h). D Cell cycle analysis after BrdU staining in MOLT-4 and NALM-6 cell lines exposed to proscillaridin A (5 nM, 48h). Cell fluorescence was measured by flow cytometry (* indicates P<0.05; Two-way ANOVA; n=3). E Metascape analysis of genes upregulated by proscillaridin A treatment (5 nM; 48h). (PDF 905 kb)
Additional file 2 of Transcriptomic analysis of poco1, a mitochondrial pentatricopeptide repeat protein mutant in Arabidopsis thaliana
Creators: name: Emami, Hossein
name: Kumar, Abhishek
name: Kempken, Frank
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Figure S1. GO enrichment terms. Top 5 molecular functions (GO:MF) and top 30 biological processes (GO:BP) for up- and down-regulated genes in pre-inflorescence-inflorescence, inflorescence-flowering and inflorescence-inflorescence are shown. The adjusted p-values (Padj) are shown in negative log10 scale.
Fermionic Topological Order on Generic Triangulations
Creators: name: Prodan, Emil
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mathematical Physics (math-ph)
subject: Operator Algebras (math.OA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Consider a finite triangulation of a surface $M$ of genus $g$ and assume that spin-less fermions populate the edges of the triangulation. The quantum dynamics of such particles takes place inside the algebra of canonical anti-commutation relations (CAR). Following Kitaev's work on toric models, we identify a sub-algebra of CAR generated by elements associated to the triangles and vertices of the triangulation. We show that any Hamiltonian drawn from this sub-algebra displays topological spectral degeneracy. More precisely, if $\mathcal P$ is any of its spectral projections, the Booleanization of the fundmental group $π_1(M)$ can be embedded inside the group of invertible elements of the corner algebra $\mathcal P \, {\rm CAR} \, \mathcal P$. As a consequence, $\mathcal P$ decomposes in $4^g$ lower projections. Furthermore, a projective representation of $\mathbb Z_2^{4g}$ is also explicitly constructed inside this corner algebra. Key to all these is a presentation of CAR as a crossed product with the Boolean group $(2^X,Δ)$, where $X$ is the set of fermion sites and $Δ$ is the symmetric difference.
description: Ann. Henri Poincar\'e (2021)
title: Health Economics of Reproductive Carrier Screening
Creators: name: Wang, Tianjiao
Publisher: name: Griffith University
Year: 2023
Subjects: subject: reproductive carrier screening
subject: genetics
subject: economic evaluation
subject: health economics

description: Background: Autosomal recessive (AR) and X-linked (XL) conditions are collectively common and place physical, psychological, and financial burden on patients and their families, as well as financial burden on society. Many conditions have no specific treatments available and can only be managed through supportive care. Gene therapies for treating a small number of these conditions are available, but these treatments can cost millions of dollars and the cost effectiveness is largely unknown. Reproductive carrier screening is a strategy to identify the carrier status of couples for AR and/or XL conditions, which can give couples the autonomy to make informed reproductive decisions. In 2018, the Australian government launched a national project named Mackenzie’s Mission (AU$20 million), to determine the evidence for making reproductive carrier screening free for all pregnant or preconception couples in Australia. Aim & objectives: The overall aim of this thesis is to investigate the economic evidence for implementing reproductive carrier screening in Australia. To achieve this aim, the six objectives are as follow: Objective 1: To develop a cost-effectiveness analysis of AVXS-101 and nusinersen for treating spinal muscular atrophy (SMA). Objective 2: To investigate the economic burden of AR and XL conditions in Australia. Objective 3: To develop an overview of existing carrier screening panels for AR and XL conditions. Objective 4: To conduct a systematic review of the clinical utility of reproductive carrier screening program. Objective 5: To conduct a systematic review of economic evaluations of reproductive carrier screening program. Objective 6: To explore if reproductive carrier screening is cost-effective for AR and XL conditions for preconception and pregnant couples.
Robust Low-Rank Tensor Ring Completion
Creators: name: Huang, Huyan
name: Liu, Yipeng
name: Zhu, Ce
Publisher: name: arXiv
Year: 2019
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Low-rank tensor completion recovers missing entries based on different tensor decompositions. Due to its outstanding performance in exploiting some higher-order data structure, low rank tensor ring has been applied in tensor completion. To further deal with its sensitivity to sparse component as it does in tensor principle component analysis, we propose robust tensor ring completion (RTRC), which separates latent low-rank tensor component from sparse component with limited number of measurements. The low rank tensor component is constrained by the weighted sum of nuclear norms of its balanced unfoldings, while the sparse component is regularized by its l1 norm. We analyze the RTRC model and gives the exact recovery guarantee. The alternating direction method of multipliers is used to divide the problem into several sub-problems with fast solutions. In numerical experiments, we verify the recovery condition of the proposed method on synthetic data, and show the proposed method outperforms the state-of-the-art ones in terms of both accuracy and computational complexity in a number of real-world data based tasks, i.e., light-field image recovery, shadow removal in face images, and background extraction in color video.
أصول الدوحة و قطر البيوت التراثية القطرية - كتيب الأنشطة المرسية
Creators: name: Rowbotham, Annie
name: Sherif, Shaima
Publisher: name: Manara - Qatar Research Repository
Year: 2023
Subjects: classificationCode: 43
subject: History, heritage and archaeology
classificationCode: 4302
subject: Heritage, archive and museum studies
classificationCode: 4301
subject: Archaeology

description: This item is an Activity Pack produced by UCL Qatar as part of the The Origins of Doha and Qatar Project, and is part of Origins of Doha and Qatar: Traditional Qatari Homes School Pack - Arabic collection.  The Activity Pack is for 6 - 11 years age groups. This work was illustrated by Sumam Azzam.
Development of next-generation voltage-gated calcium channel inhibitors using engineered nanobodies
Creators: Morgenstern, Travis James
Publisher: name: Columbia University
Year: 2021
Subjects: Pharmacology
Biophysics
Cytology
Immunoglobulins
Protein binding
Cardiovascular system--Diseases--Etiology
Nervous system--Diseases--Etiology

description: High-voltage activated calcium channels underlie many critical functions in excitable cells and their dysfunction has been implicated in a myriad of cardiovascular and neurological diseases. These channels are multimeric protein complexes composed of α1, β, and α2δ subunits; currently, all calcium channel blockers target either the pore-forming α1 or extracellular-facing α2δ auxiliary subunit. These pharmacological agents have been invaluable in delineating the individual function of each subunit within excitable cells that express multiple calcium channels. Yet, no current tool allows similar pharmacological dissection of individual cytosolic β subunits, preventing our understanding of how distinct β subunits affect the function of calcium channel complexes. Further, small-molecule calcium channel blockers are highly-valued therapeutics for certain conditions, yet their propensity for off-target effects precludes their use in other diseases. In certain applications, genetically-encoded calcium channel blockers may enable channel inhibition with greater tissue-precision and versatility than is achievable with small molecules. Previous work that found the family of RGK proteins powerfully inhibits high-voltage activated calcium channels in part via an association with the β subunit. However, the myriad functions of RGK proteins limit the utility of this approach. In this work, we circumvent this issue by isolating single-domain antibodies (nanobodies) that target the auxiliary CaVβ subunit. We then paired these nanobodies with the powerful enzymatic activity of the HECT domain E3 ubiquitin ligase Nedd4L, to selectively target the calcium channel for ubiquitination. We found this strategy effectively eliminated functional calcium channels from the surface of HEK293 cells, myocytes, and DRG neurons. This modular design permitted us to characterize a pan-β inhibitor (CaV-aβlator) in chapter 2 while refining the approach with a β1-selective channel inhibitor in chapter 3. In chapter 4 I demonstrate that it is possible to hijack the endogenous ubiquitin machinery of the cell by creating Divas: divalent nanobodies that are capable of recruiting endogenous Nedd4L to regulate the calcium channel. Finally, we demonstrate the potential for these genetically-encoded calcium inhibitors to be employed as therapeutic agents by targeting CaV-aβlator to sensory neurons in order to reduce the onset of neuropathic pain. Altogether, this work lays the foundation for nanobody-based genetically-encoded calcium channel inhibitors that have the potential to achieve superior precision in regards to molecular and tissue specificity.
Artificial Intelligence - Virtual Assist Smart Schedular
Creators: name: Saleem, Salman
Publisher: name: Zenodo
Year: 2020

description: With the chaotic hustle and bustle along with the out pour of daily tasks, one suffers from managing their task effectively. For example, if there is a call of numerous meetings via email; going through each email and mapping them individually on a daily schedule chart will be a tedious task. Virtual Assist is an android application that is a personal scheduler which will manage and prioritize the task effectively.
Stability of topologically protected edge states in nonlinear quantum walks: Additional bifurcations unique to Floquet systems
Creators: name: Mochizuki, Ken
name: Kawakami, Norio
name: Obuse, Hideaki
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: Mathematical Physics (math-ph)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: Recently, effects of nonlinearity on topologically nontrivial systems have attracted attention and the stability of topologically protected edge states has been studied for a quantum walk with nonlinear effects, which is akin to time-periodically driven systems (Floquet systems). In the previous work, it has been found that the edge states can be stable attractors or unstable repellers depending on their intrinsic topological property, while the stability is not affected by the strength of nonlinearity. In the present work, we find additional bifurcations at which edge states change from stable attractors to unstable repellers with increasing the strength of nonlinearity in nonlinear quantum walks, for the first time. The new bifurcations are unique to Floquet systems, since we take dynamical properties of Floquet systems into consideration by directly applying the time-evolution operator of the quantum walks to the linear stability analysis. Our results shed new light on nonlinear effects on topological edge states in Floquet systems.
description: 28 pages, 11 figures
Development of small-angle scattering pair distribution function analysis techniques and application to nanoparticles assemblies
Creators: Liu, Chia-Hao
Publisher: name: Columbia University
Year: 2020
Subjects: Applied physics
Materials science
Nanostructured materials
Distribution (Probability theory)
Small-angle scattering

description: With the improvement in synthesis method, a variety of nanoparticles (NPs) with nearly uniform distribution in size and morphology are now available to scientists. This progress opens a new opportunity of assembling these high quality nanoparticles into metamaterial - nanoparticle assemblies (NPAs). The properties of NPA depend on the interactions between constituent NPs, therefore NPA offer a distinct advantage in designing material properties that are not available in the bulk phase (crystal) or discrete phase (nanoparticle). Novel application of NPA in modern devices, such as solar cells and field effect transistors, had also been demonstrated. The spatial arrangements of NPs is the key factor to their interactions, therefore, it is crucial to characterize the structure of NPA quantitatively. The technique of diffraction plays an unique role for characterizing NPA structure, as it not only offers the structural type, which may also be obtained from imagine technique, but also yields structural information in three-dimension, such inter-particle distance and the range of structural coherence of the packing order. Traditionally, the diffraction analysis is based on crystallography and is carried out in reciprocal space. However, it has been known local structure is overlooked in this kind of crystallographic analysis, which places a challenge for have a comprehensive understanding of the NPA structure. The pair distribution function (PDF) analysis, which is powerful in probing local structures for atomic systems, serves as a promising tool for characterizing NPA structure. How- ever, the approach of using PDF analysis for NPA structure characterization has barely been explored. In this thesis, I will present the methodological developments of the PDF technique. Starting from presenting a machine-learning-assisted approach for predicting the space group of its structure from the PDF, I will be focusing on the aspect of accelerating the structure modeling steps with PDF. Next, the development of pair distribution function analysis in small-angle scattering domain sasPDF will be introduced, including software package PDFgetX3 which is aiming to facilitate the extraction of PDF from small-angle scattering data quickly. The approach of sasPDF is validated against three representative structures across different levels of structural order. Finally, the example of applying sasPDF method to identify the jamming transition signature in polymer-ligated NPA is introduced, followed by another example of discovering multiply-twinned structure from the reprogramming of DNA-ligated NPA.
title: Framework for the Future
title: The Possibility of Majority Voting within the United Nations Framework Convention on Climate Change (UNFCCC)
titleType: Subtitle
Creators: name: Kemp, Luke
Publisher: name: Freie Universität Berlin
Year: 2014
Subjects: subject: climate policy
subject: UNFCCC
subject: United Nations
subject: international organizations
subject: global environmental policy
subject: 300 Sozialwissenschaften
subject: 300 Sozialwissenschaften::320 Politikwissenschaft::327 Internationale Beziehungen

description: The United Nations Framework Convention on Climate Change (UNFCCC) is struggling in its attempts to address the threat of anthropogenic climate change and create an effective post-Kyoto international climate agreement. One substantial part of the problem is con-sensus decision making within the Convention, which effectively gives every party a veto over the process. Majority voting is one potential alternative which is already being dis-cussed within the UNFCCC. A comparative analysis of consensus and majority voting sug-gests that majority voting is superior in terms of both efficiency and effectiveness since it is a better consensus-builder, a speedier decision making process and provides opportuni-ties for a semi-global approach to international climate policy. The objective in this paper is to investigate how majority voting could be implemented in the UNFCCC and to consider politically feasible and effective approaches to voting arrangements for the Convention. Implementing majority voting in the Convention faces legal, political and institutional ob-stacles. While it has growing support from some states, others remain staunchly opposed, with concerns over voting on financial matters being particularly sensitive. A type of Lay-ered Majority Voting with larger majorities for financial and substantial matters is consid- ered to be the optimal approach in balancing political feasibility and effectiveness. A weighted voting system differentiated on the basis of mitigation commitments, vulnerabil-ity and population (Common but Differentiated Voting) is proposed as an ideal approach. Despite these possibilities a change in decision making will likely require a crisis to cata-lyse the necessary political will and break the current path dependency that has been built around consensus.
Development of leg motor neurons in drosophila melanogaster
Creators: Baek, Myungin
Publisher: name: Columbia University
Year: 2011
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Drosophila larval and adult stage forms are very different. Drosophila larvae move using undulatory body muscle contractions, while adult flies walk and fly using legs and wings. Leg motor neurons control multi-jointed leg movement by coordinately regulating leg muscle contractions. With the aim of understanding how Drosophila leg motor neurons are specified, in Chapter One, I give a general introduction of the mechanisms that regulate motor neuron generation and specification. In Chapter Two, I show that adult Drosophila leg motor neurons are mostly generated de novo during larval stages in a lineage dependent manner. Although leg motor neurons are born from 11 lineages, nearly two thirds of leg motor neurons are born from two major lineages: Lin A and Lin B. I describe the individual leg motor neuron birth orders, axonal and dendritic morphologies by using single cell labeling methods. Each motor neuron that has unique axonal targeting and dendritic architecture is born in a stereotypic birth order from a specific lineage. Leg motor neurons targeting similar muscles share dendritic territory in the CNS and subsequently form a dendritic myotopic map in the CNS. These findings provide critical information about how individual leg motor neurons are generated, and how individual leg motor neuron axons and dendrites look like. In Chapter Three, I describe the results of a candidate gene approach. In vertebrate systems, Hox genes and Hox cofactors regulate spinal cord motor neuron identity. Although much work has been done addressing the function of Hox genes and Hox cofactors in vertebrate motor neuron development, the function of Hox genes and Hox cofactors in motor neuron dendritic arborization has not been clearly addressed. With this aim in mind, I describe the function of Hox genes and Hox cofactors in Drosophila leg motor neuron development by removing Hox genes and Hox cofactors in both entire lineages and individual motor neurons. I show that Hox genes and Hox cofactors are required for motor neuron survival, and proper axonal and dendritic targeting. In Chapter Four, I discuss about how segmental and temporal identities of leg motor neurons are specified and how the axonal targeting of leg motor neurons at the early stage is achieved. Finally, in the Appendix, I show my attempts to find leg motor neuron specific molecular markers.
title: Discrepancy between integral and local composition in off-stoichiometric Cu2ZnSnSe4 kesterites
title: A pitfall for classification
titleType: Subtitle
Creators: name: Schoeppe, Philipp
name: Gurieva, Galina
name: Giraldo, Sergio
name: Martinez-Criado, Gema
name: Ronning, Carsten
name: Saucedo, Edgardo
name: Schorr, Susan
name: Schnohr, Claudia S.
Publisher: name: Freie Universität Berlin
Year: 2017
Subjects: subject: 500 Naturwissenschaften und Mathematik

description: High-efficiency kesterite-based thin film solar cells typically feature Cu- poor, Zn-rich absorbers although secondary phases occur easily in non- stoichiometric Cu2ZnSnSe4. We therefore applied high-resolution X-ray fluorescence analysis using a synchrotron nanobeam to study the local composition of a CZTSe cross section lamella cut from a sample with an integral composition of Zn/Sn = 1.37 and Cu/(Zn+Sn) = 0.55. We find submicrometer-sized ZnSe-, SnSe/SnSe2-, and even CuSe/Cu2Se-like secondary phases, while the local compositions of the kesterite are highly Zn-rich yet barely Cu-poor with 1.5 ≤ Zn/Sn ≤ 2.2 and Cu/(Zn+Sn) ∼ 1.0. Consequently, great care must be taken when relating the integral composition to other material properties including the device performance.
Field-dependent surface impedance tensor in amorphous wires with two types of magnetic anisotropy: helical and circumferential
Creators: name: Makhnovskiy, D. P.
name: Panina, L. V.
name: Mapps, D. J.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: This paper concerns the theoretical and experimental investigation of the magneto-impedance (MI) effect in amorphous wires in terms of the surface impedance tensor. Physical concepts of MI and problems of significant practical importance are discussed using the results obtained. The theoretical analysis is based on employing the asymptotic-series expansion method of solving the Maxwell equations for a ferromagnetic wire with an ac permeability tensor of a general form associated with magnetisation rotation. The magnetic structure-dependent impedance tensor is calculated for any frequency and external magnetic field, and is not restricted to the case when only strong skin-effect is present. This approach allows us to develop a rigorous quantitative analysis of MI characteristics in wires, depending on the type of magnetic anisotropy, the magnitude of dc bias current, and an excitation method. The theoretical model has been tested by comparing the obtained results with experiment. For the sake of an adequate comparison, the full impedance tensor is measured in CoFeSiB and CoSiB amorphous wires having a circumferential and helical anisotropy, respectively, by determining the S21 parameter. In cases, when the rotational dynamics is responsible for the impedance behaviour, there is a reasonable agreement between the experimental and theoretical results. Such effects as the ac biased asymmetrical MI in wires with a circumferential anisotropy, the transformation in MI behaviour caused by a dc current (from that having a symmetric hysteresis to an asymmetric anhysteretic one) in wires with a helical anisotropy are discussed.
description: PDF, 18 pages
Translating CRediT into Russian
Creators: name: Kochetkov, Dmitry
name: Popova, Natalia
name: Kochetkova, Irina
Publisher: name: Zenodo
Year: 2024

description: This file describes the process of CRedit taxonomy translation into Russian within the framework of Contributorship Collaboration. Dmitry Kochetkov prepared the original draft ('original'). Irina Kochetkova commented on the original draft and enriched the translation with alternatives ('enriched'). Dmitry Kochetkov conducted back translation with Yandex.Translate scoring the highest in DiBiMT benchmark (with analysis of alternatives provided by the software) ('back_translation'). Translation 3 (t_3) was taken from https://doi.org/10.56414/jeac.2022.24. Dmitry Kochetkov drafted the summarizing version; Natalia Popova commented on it ('intermediate'). The final version was discussed by all the contributors ('final').
title: Analyzing meaning
title: An introduction to semantics and pragmatics
titleType: Subtitle
Creators: name: Kroeger, Paul
Publisher: name: Freie Universität Berlin
Year: 2018
Subjects: subject: 400 Sprache::410 Linguistik

description: This book provides an introduction to the study of meaning in human language, from a linguistic perspective. It covers a fairly broad range of topics, including lexical semantics, compositional semantics, and pragmatics. The chapters are organized into six units: (1) Foundational concepts; (2) Word meanings; (3) Implicature (including indirect speech acts); (4) Compositional semantics; (5) Modals, conditionals, and causation; (6) Tense & aspect. Most of the chapters include exercises which can be used for class discussion and/or homework assignments, and each chapter contains references for additional reading on the topics covered. As the title indicates, this book is truly an INTRODUCTION: it provides a solid foundation which will prepare students to take more advanced and specialized courses in semantics and/or pragmatics. It is also intended as a reference for fieldworkers doing primary research on under-documented languages, to help them write grammatical descriptions that deal carefully and clearly with semantic issues. The approach adopted here is largely descriptive and non-formal (or, in some places, semi-formal), although some basic logical notation is introduced. The book is written at level which should be appropriate for advanced undergraduate or beginning graduate students. It presupposes some previous coursework in linguistics, but does not presuppose any background in formal logic or set theory.
MOESM2 of Towards creating an extended metabolic model (EMM) for E. coli using enzyme promiscuity prediction and metabolomics data
Creators: name: Amin, Sara
name: Chavez, Elizabeth
name: Porokhin, Vladimir
name: Nair, Nikhil
name: Hassoun, Soha
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 2. Results of Flux Balance Analysis and Flux Variability Analysis for the added EMMA reactions.
Topological Ring-Cavity Laser Formed by Honeycomb Photonic Crystals
Creators: name: Sun, Xiao-Chen
name: Hu, Xiao
Publisher: name: arXiv
Year: 2019
Subjects: subject: Optics (physics.optics)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We clarify theoretically that the topological ring-cavity (TRC) modes propagating along the interface between two honeycomb-type photonic crystals distinct in topology can be exploited for achieving stable single-mode lasing, with the maximal intensity larger than a whispering-gallery-mode counterpart by order of magnitude. Especially, we show that the TRC modes located at the bulk bandgap center benefit maximally from the gain profile since they are most concentrated and uniform along the ring cavity, and that, inheriting from the Dirac-like dispersion of topological interface states, they are separated in frequency from each other and from other photonic modes, both favoring intrinsically single-mode lasing. A TRC mode running in a specific direction with desired orbital angular momentum can be stimulated selectively by injecting circularly polarized light. The TRC laser proposed in the present work can be fabricated by means of advanced semiconductor nanotechnologies, which generates chiral laser beams ideal for novel photonic functions.
Additional file 2: of Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation
Creators: name: Costa, Elodie Da
name: Armaos, Gregory
name: McInnes, Gabrielle
name: Beaudry, Annie
name: Moquin-Beaudry, Gaël
name: Bertrand-Lehouillier, Virginie
name: Caron, Maxime
name: Richer, Chantal
name: St-Onge, Pascal
name: Johnson, Jeffrey
name: Nevan Krogan
name: Sai, Yuka
name: Downey, Michael
name: Moutih Rafei
name: Boileau, Meaghan
name: Eppert, Kolja
name: Flores-Díaz, Ema
name: Haman, André
name: Hoang, Trang
name: Sinnett, Daniel
name: Beauséjour, Christian
name: McGraw, Serge
name: Raynal, Noël
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Figure S1. MYC Expression Correlates with Proscillaridin A Anticancer Efficacy. A Upper panel, half maximal inhibitory concentration (IC50) after a 24h proscillaridin A treatment (ranging from 1 nM to 100 μM) in a panel of human cancer cell lines (n=4). Lower panel, MYC protein level in each untreated cell line, assessed by western blotting. ACTIN was used as a loading control (n ≥ 3). B Graph showing MYC expression (relative to ACTIN) compared to proscillaridin A IC50 (24h) in 14 cancer cell lines. Correlation was evaluated by linear regression analysis; P-value is shown on the graph (n=3). C Representative pictures of transformed primary human fibroblasts before and after transduction with RASV12, MYC and RASV12/MYC were taken by light microscopy (400X magnification). D and E MYC expression was assessed by Western blotting in WT and MYC-transduced MOLT-4 cells (D) and REH cells (E). MYC expression was calculated as a ratio over ACTIN levels (*indicates P<0.05; One-way ANOVA; n = 3). IC50 values after 24h proscillaridin A treatment (ranging from 0.1 nM to 1 μM) in MOLT-4 cells (D) and REH cells (E) (n ≥ 3). F Time course experiment in NALM-6 cells treated with 5 nM for up to 96h. MYC expression was calculated as a ratio over ACTIN levels (*indicates P<0.05; One-way ANOVA; n = 3). (PDF 1640 kb)
Scylacosauridae Broom 1903
Creators: name: Huttenlocker, Adam
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Synapsida
Therapsida
Scylacosauridae

description: Scylacosauridae (six characters)  4. Rostrum is moderately long and about as high as it is broad (2).
7. A shallow preorbital depression anterior to a thickened ridge on the anterior margin of the orbit is present, extending anteroventrally from the lacrimal to the canine buttress of the maxilla (1).
15. Orbit positioned relatively high, elevated to or above the dorsal temporal margin (0). (Reversal to the primitive therapsid condition; conv. in baurioids.)
 16. Anterior border of orbit located on transverse midline of skull (2). (Modified from van den Heever, 1994; conv. in Olivierosuchus, Promoschorhynchus and baurioids.)
 49. Interpterygoid vacuity of adults extremely reduced (1). (From Kemp, 1972a; conv. in Theriognathus.)
 75. Upper incisors numerous, more than five (1). (Conv. in Anomodontia, non- Charassognathus cynodonts and all baurioids except Bauria.)
description: Published as part of Huttenlocker, Adam, 2009, An investigation into the cladistic relationships and monophyly of therocephalian therapsids (Amniota: Synapsida), pp. 865-891 in Zoological Journal of the Linnean Society 157 (4) on page 888, DOI: 10.1111/j.1096-3642.2009.00538.x, http://zenodo.org/record/5443291
Development of semi-automated steady state exogenous contrast cerebral blood volume mapping
Creators: Provenzano, Frank Anthony
Publisher: name: Columbia University
Year: 2016
Subjects: subject: Blood volume
subject: Magnetic resonance imaging
subject: Blood volume--Measurement
subject: Brain--Imaging
subject: Brain--Magnetic resonance imaging
subject: Magnetic resonance imaging--Data processing
subject: Cerebral circulation
subject: Biomedical engineering
subject: Neurosciences
subject: FOS: Clinical medicine

description: Functional magnetic resonance imaging (fMRI) as it exists, in its many forms and vari- ants, has revolutionized the fields of neurology and psychology by revealing functional differences non-invasively. Although blood oxygenation level dependent (BOLD) fMRI is used interchangeably with fMRI, it measures one single difference in a phys- iological measurement using a set sequence. As such, there are other established changes in the brain that relate to blood movement and capacity that can also be measured using MRI. One measure, exogenous steady state cerebral blood volume, uses a bolus routine contrast agent administered intravenously alongside a pair of high resolution ‘structural-like’ MRI images to provide detailed information within small cortical and subcortical structures.
      In this thesis I design a semi-automated algorithm to generate maps of steady state exogenous cerebral blood volume magnetic resonance imaging datasets. To do this I developed an algorithm and tested it on existing MRI scanning protocols. A series of automated pre-processing steps are developed and tested, including automated scan flagging for artifacts and requisite vascular segmentation. Then, a methodology is developed to create cerebral blood volume (CBV) region of interest (ROI) masks that can then be applied on an existing database to test known CBV dysfunction in a group of patients at high risk for psychosis. Finally, we develop an experiment to see if template based cerebral blood alterations co-registered with class segmentation maps have any positive predictive value in determining disease state in a well characterized cohort of five age-matched groups in an Alzheimer’s disease neuroimaging study.
title: The EU as an Autonomous Defense Actor
Creators: name: Koenig, Nicole
Publisher: name: Hertie School
Year: 2021

description: The defence angle of European strategic autonomy remains sensitive and contested. In this chapter of a report published by the Finnish Institute of International Relations (FIIA) Nicole Koenig reviews the EU's defence cooperation initiatives since 2016 and assesses progress along the political, institutional and material dimensions of strategic autonomy. She shows that divergent national strategic cultures and threat perceptions continue to stand in the way of political autonomy while progress on the institutional and material dimensions is gradual. The renewal of Atlanticism triggered by Biden’s election and the pandemic’s uncertain impact on defence spending and collaboration risk broadening the persisting gap between ambition and reality. The author calls upon the EU and its member states to strengthen all three dimensions of autonomy and provides guidance for the next steps.
Quantum Lefschetz Hyperplane Theorem
Creators: name: Lee, Yuan-Pin
Publisher: name: arXiv
Year: 2000
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: The mirror theorem is generalized to any smooth projective variety X. That is, a fundamental relation between the Gromov-Witten invariants of X and Gromov-Witten invariants of complete intersections Y in X is established.
title: Teampraxis – wie genau geht das eigentlich?
Creators: name: Reddemann, Olaf
name: Aden, Ilka
name: Herrmann, Markus
name: Rüter, Gernot
name: Heidinger, Dorothe
name: Hämel, Kerstin
name: Schulz, Sven
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die DEGAM-Zukunftsposition Nr.2 lautet: „Die Hausarztpraxis der Zukunft ist eine Teampraxis“. Gute allgemeinmedizinische Versorgung erfordert Teamarbeit, und die Versorgung der Zukunft wird auch davon abhängen, geeignete Teamkonzepte zu fördern und weiterzuentwickeln.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin
The High-Mass Protostellar Population of a Massive Infrared Dark Cloud
Creators: name: Moser, Emily
name: Liu, Mengyao
name: Tan, Jonathan C.
name: Lim, Wanggi
name: Zhang, Yichen
name: Farias, Juan Pablo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We conduct a census of the high-mass protostellar population of the $\sim70,000\:M_\odot$ Infrared Dark Cloud (IRDC) G028.37+00.07, identifying 35 sources based on their $70\:μ$m emission, as reported in the {\it Herschel} Hi-GAL catalog of Molinari et al. (2016). We perform aperture photometry to construct spectral energy distributions (SEDs), which are then fit with the massive protostar models of Zhang & Tan (2018). We find that the sources span a range of isotropic luminosities from $\sim$20 to 4,500$\:L_\odot$. The most luminous sources are predicted to have current protostellar masses of $m_{*}\sim10\:M_\odot$ forming from cores of mass $M_{c}\sim40$ to $400\:M_\odot$. The least luminous sources in our sample are predicted to be protostars with masses as low as $\sim 0.5\:M_\odot$ forming from cores with $M_{c}\sim10\:M_\odot$, which are the minimum values explored in the protostellar model grid. The detected protostellar population has a total estimated protostellar mass of $M_{*}\sim 100\:M_\odot$. Allowing for completeness corrections, which are constrained by comparison with an ALMA study in part of the cloud, we estimate a star formation efficiency per free-fall time of $\sim3\%$ in the IRDC. Finally, analyzing the spatial distribution of the sources, we find relatively low degrees of central concentration of the protostars. The protostars, including the most massive ones, do not appear to be especially centrally concentrated in the protocluster as defined by the IRDC boundary.
description: 18 pages, accepted to ApJ, comments welcome
title: Die Kur als Heilmittel und Sehnsuchtsort. Vom hausärztlichen Spagat zwischen Patientenwohl, Patientenwunsch und gesellschaftlichen Ansprüchen
Creators: name: Meyer, Fritz
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Badekuren gelten seit historischen Zeiten als Heilmittel. Während in der Antike Thermalquellen schon therapeutisch genutzt wurden, dienten öffentliche Badestuben im Spätmittelalter eher marginal der Körperpflege und mehr den Ausschweifungen jeglicher Art. Dies förderte[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin
Kronecker products of projective representations of translation groups
Creators: name: Florek, Wojciech
Publisher: name: arXiv
Year: 1997
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Projective irreps of (Z_N)^2 can be labelled by divisors n of N. A product of two irreps, labelled by n and n', can be decomposed into projective irreps labelled by M, where M strongly depends on the arithmetic structure of N, n, n' and their relations (gcd, lcm etc.). Such decompostion describes two important physical effects: (i) changes of a magnetic period of the crystal lattice (with unchaged crystal period N); (2) each representation can be related with a charged particle moving in an external magnetic field and a periodic potential --- a product of (projective) irreps corresponds to interaction of particles with charges Q and Q', respectively, and the decomposition corresponds to a particle with the charg Q''=Q+Q'.
description: LaTeX 2.09, 7 pages, uses AMSSYM v2.2; presented as a poster at WigSym '97
Development of high fidelity cardiac tissue engineering platforms by biophysical signaling: in vitro models and in vivo repair
Creators: Godier-Furnemont, Amandine Florence Ghislaine
Publisher: name: Columbia University
Year: 2015
Subjects: Stem cells
Microelectromechanical systems
Cardiovascular system--Diseases--Treatment
Tissue engineering
Biomedical engineering

description: Cardiovascular disease (CVD) is broadly characterized by a loss of global function, exacerbated by a very limited ability for the heart to regenerate itself following injury. CVD remains the leading cause of death in the United States and the leading citation in hospital discharges. The overall concept of this dissertation is to investigate the use of biophysical signals that drive physiologic maturation of myocardium, and lead to its deterioration in disease. By incorporating biophysical signaling into cardiac tissue engineering methods, the aim is to generate high fidelity engineered platforms for cell delivery and maturation of surrogate muscle, while understanding the cues that lead to pathological cell fate in disease.
      The first part of this thesis describes the development of a composite scaffold, derived from human myocardium, to use as a delivery platform of mesenchymal stem cells to the heart. Through biochemical signaling, we are able to modulate MSC phenotype, and propose a mechanism through which angio- and arteriogenesis of the heart leading to global functional improvements, following myocardial infarction, may be attributed. We further demonstrate cardioprotection of host myocardium in a setting of acute injury by exploiting non-invasive radioimaging techniques. The mechanism through which we can attribute cell mobilization to the infarct bed is further explored in patient-derived myocardium, to understand how this pathway remains relevant in chronic heart failure. The second focus of the thesis is the use of electro-mechanical stimulation to generate high fidelity Engineered Heart Muscle (EHM). We report that electro-mechanical stimulation of EHM at near-physiologic frequency leads to development and maturation of Calcium handling and the T- tubular network, as well as improved functionality and positive force frequency relationship. Lastly, we return to human myocardium as platform understand regulation of cardiomyocyte function by the extracellular matrix. Here, we seek to understand how the ECM from different disease states (eg. non-diseased, ischemic, non-ischemic) affects cell phenotype. Specifically, can bona fide engineered myocardium successfully integrate and remodel diseased ECM? Using stem cell derived cardiomyocytes and patient-derived decellularized myocardium to generated engineered myocardium (hhEMs), we report that hhEMs mimic native myogenic expression patterns representative of their failing- and non-failing heart tissue.
title: Laborwerte im Zeitalter von FAKE-NEWS
Creators: name: Engel, Bettina
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Ich dachte immer es gäbe indiskutable Fakten in der Medizin, an die man sich halten kann – Laborwerte gehörten dazu! Jedoch bin ich bei der Recherche über ein anderes Thema über die sog. „Richtlinie der Bundesärztekammer zur Qualitätssicherung[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin