Additional file 1 of Advanced respiratory mechanics assessment in mechanically ventilated obese and non-obese patients with or without acute respiratory distress syndrome
Creators: name: Beloncle, François M.
name: Richard, Jean-Christophe
name: Merdji, Hamid
name: Desprez, Christophe
name: Pavlovsky, Bertrand
name: Yvin, Elise
name: Piquilloud, Lise
name: Olivier, Pierre-Yves
name: Chean, Dara
name: Studer, Antoine
name: Courtais, Antonin
name: Campfort, Maëva
name: Rahmani, Hassene
name: Lesimple, Arnaud
name: Meziani, Ferhat
name: Mercat, Alain
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Hematology

description: Additional file 1: Table S1. Main characteristics of the patients according to the presence or not of ARDS and obesity. Table S2. Gas exchange and respiratory mechanics of the patients according to the presence or not of ARDS and obesity. Table S3. Main characteristics of the patients according to the ratio of lung to respiratory system elastance (EL/ERS). Table S4. Gas exchange and respiratory mechanics of the patients according to the ratio of lung to respiratory system elastance (EL/ERS). Fig. S1. Correlations between the ratio of partial pressure of arterial oxygen over fraction of inspired oxygen (PaO2/FiO2, A) and ventilatory ratio (VR, B), and body mass index (BMI) in patients with or without acute respiratory distress syndrome (ARDS). Fig. S2. Distribution of respiratory system compliance (CRS/PBW, A), lung compliances (CL/PBW, B) and end-expiratory lung volume (EELV/PBW, C) normalized to predicted body weight in patients categorized according to the presence or not of obesity and the presence or not of acute respiratory distress syndrome (ARDS). Boxplots display medians, 10th, 25th, 75th, and 90th percentiles. p-values represent the comparisons between obese and non-obese patients and between ARDS and non-ARDS patients. Fig. S3. Distribution of respiratory system compliances considering airway opening pressure normalized to predicted body weight (CRS-AOP/PBW). A. Patients categorized according to the presence or not of obesity and acute respiratory distress syndrome (ARDS). p-value represents the overall comparison between the four groups of patients. *, p &lt; 0.05; 0**, p &lt; 0.01; ***, p &lt; 0.001 (pairwise comparisons with Bonferroni correction). B Patients categorized according to the presence or not of obesity and the presence or not of ARDS. p-values represent the comparisons between obese and non-obese patients and between ARDS and non-ARDS patients. Boxplots display medians, 10th, 25th, 75th, and 90th percentiles. Fig. S4. Correlations between respiratory system compliance (CRS/PBW, A) and end-expiratory lung volume normalized to predicted body weight (EELV/PBW, B) and body mass index (BMI) in patients with or without acute respiratory distress syndrome (ARDS). Fig. S5. Correlations between respiratory system compliance (CRS) and end-expiratory lung volume (EELV) at positive end-expiratory pressure of 5 cmH2O in obese and non-obese patients with or without acute respiratory distress syndrome (ARDS). Fig. S6. Distribution of chest wall compliance (CCW, A) and end-expiratory esophageal pressure (Peso expi, B) in patients categorized according to the presence or not of obesity and the presence or not of acute respiratory distress syndrome (ARDS). Boxplots display medians, 10th, 25th, 75th, and 90th percentiles. p-values represent the comparisons between obese and non-obese patients and between ARDS and non-ARDS patients. Fig. S7. Correlations between chest wall compliance (Ccw, A) and expiratory esophageal pressure (Peso expi, B) and body mass index (BMI) in patients with or without acute respiratory distress syndrome (ARDS). Fig. S8. Distribution of lung to respiratory system elastance ratio (EL/ERS). A Patients categorized according to the presence or not of obesity and acute respiratory distress syndrome (ARDS). p-value represents the overall comparison between the four groups of patients. B Patients categorized according to the presence or not of obesity and the presence or not of ARDS. p-values represent the comparisons between obese and non-obese patients and between ARDS and non-ARDS patients. Boxplots display medians, 10th, 25th, 75th, and 90th percentiles.