cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Keypoint-Based Binocular Distance Measurement for Pedestrian Detection System on Vehicle
Creators: name: Zhao, Mingchang
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Binocular Vision
Pedestrian Detection
Distance Measurement
Driving Assist System

description: The Pedestrian Detection System (PDS) has become a significant area of research designed to protect pedestrians. Despite the huge number of research work, the most current PDSs are designed to detect pedestrians without knowing their distances from cars. In fact, a priori knowledge of the distance between a car and pedestrian allows this system to make the appropriate decision in order to avoid collisions. Typical methods of distance measurement require additional equipment (e.g., Radars) which, unfortunately, cannot identify objects. Moreover, traditional stereo-vision methods have poor precision in long-range conditions. In this thesis, we use the keypoint-based feature extraction method to generate the parallax in a binocular vision system in order to measure a detectable object; this is used instead of a disparity map. Our method enhances the tolerance to instability of a moving vehicle; and, it also enables binocular measurement systems to be equipped with a zoom lens and to have greater distance between cameras. In addition, we designed a crossover re-detection and tracking method in order to reinforce the robustness of the system (one camera helps the other reduce detection errors). Our system is able to measure the distance between cars and pedestrians; and, it can also be used efficiently to measure the distance between cars and other objects such as Traffic signs or animals. Through a real word experiment, the system shows a 7.5% margin of error in outdoor and long-range conditions.
O Papel do Policial Militar no Combate aos Crimes Cibernéticos
Creators: name: Magalhaes
Publisher: name: Zenodo
Year: 2025
Subjects: cibernetico
crimes
crimes digitais
policia
militar
enfrentamentos

description: O artigo trata do fundamental Papel do Policial Militar no Combate aos Crimes Cibernéticos, pela Polícia Militar de Minas Gerais, em especial a utilização de policiais pertencentes ao Serviço de Inteligência. suas dificuldades e êxitos
Receptor Heterodimerization and Co-Receptor Engagement in TLR2 Activation Induced by MIC1 and MIC4 from Toxoplasma gondii
Creators: name: Costa Mendonça-Natividade, Flávia
name: Duque Lopes, Carla
name: Ricci-Azevedo, Rafael
name: Sardinha-Silva, Aline
name: Figueiredo Pinzan, Camila
name: Paiva Alegre-Maller, Ana Claudia
name: L. Nohara, Lilian
name: B. Carneiro, Alan
name: Panunto-Castelo, Ademilson
name: C. Almeida, Igor
name: Roque-Barreira, Maria Cristina
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: The microneme organelles of Toxoplasma gondii tachyzoites release protein complexes (MICs), including one composed of the transmembrane protein MIC6 plus MIC1 and MIC4. In this complex, carbohydrate recognition domains of MIC1 and MIC4 are exposed and interact with terminal sialic acid and galactose residues, respectively, of host cell glycans. Recently, we demonstrated that MIC1 and MIC4 binding to the N-glycans of Toll-like receptor (TLR) 2 and TLR4 on phagocytes triggers cell activation and pro-inflammatory cytokine production. Herein, we investigated the requirement for TLR2 heterodimerization and co-receptors in MIC-induced responses, as well as the signaling molecules involved. We used MICs to stimulate macrophages and HEK293T cells transfected with TLR2 and TLR1 or TLR6, both with or without the co-receptors CD14 and CD36. Then, the cell responses were analyzed, including nuclear factor-kappa B (NF-κB) activation and cytokine production, which showed that (1) only TLR2, among the studied factors, is crucial for MIC-induced cell activation; (2) TLR2 heterodimerization augments, but is not critical for, activation; (3) CD14 and CD36 enhance the response to MIC stimulus; and (4) MICs activate cells through a transforming growth factor beta-activated kinase 1 (TAK1)-, mammalian p38 mitogen-activated protein kinase (p38)-, and NF-κB-dependent pathway. Remarkably, among the studied factors, the interaction of MIC1 and MIC4 with TLR2 N-glycans is sufficient to induce cell activation, which promotes host protection against T. gondii infection.
L'impunité dans le contexte de l'élargissement du rôle de l'armée mexicaine : causes et risques pour la démocratie
Creators: name: Rousseau, Frédérique
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Armée
Impunité
Mexique
Droits Humains
Démocratie

description: Les médias dépeignent une image alarmante du Mexique, avec la hausse de criminalité et la guerre contre le narcotrafic. Le gouvernement a élargi le rôle des forces armées militaires mexicaines, dans le but d’enrayer les cartels de drogue et de rehausser le niveau de sécurité. Cependant, depuis cette « militarisation », une explosion de violations des droits humains, commis par des militaires envers les civils, fait surface et les militaires jouissent d’une grande impunité. Tant que les forces armées mexicaines seront protégées pour leurs transgressions, une augmentation de l’impunité est à prévoir, ce qui pourrait conduire à la stagnation de la démocratie ou à sa régression (slow death). Cette thèse se penche sur trois causes de l’impunité – l’autonomie, les transgressions de l’autorité et les problèmes structurels du système de justice militaire – afin de mieux comprendre les conséquences qu’elles peuvent avoir sur la démocratie mexicaine, encore jeune.
Comparison of direct digitization current sensing circuits for EIS
Creators: name: Rajabzadeh, Mahdi
name: Häberle, Matthias
name: Ortmanns, Maurits
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Current readout
subject: Sigma delta modulator,
subject: Direct digitization
subject: Current-input CTSDM
subject: FIR-DAC
subject: DDC 620 / Engineering & allied operations
subject: Electric current converters
subject: Modulators (Electronics)
subject: Sigma-Delta-Wandler
subject: Digitalisierung

description: In this work, a qualitative comparison between state of the art current recorders for biomedical applications is presented. Prior work showed that direct digitizing frontends outweight their analog counterparts. This work performs a comparison between the direct digitization frontends, namely time-based and current-input CTSDM frontends. It is shown that time-based converters - due to usage of current conveyors to generate a low impedance node - suffer from inferior linearity. Also the trade-off between SNR versus conversion time limits their achievable SNR and the maximum input signal frequency. On the other hand, with the usage of a FIR-DAC within a current input CTSDM, the requirements of the critical first amplifier are highly relaxed. In addition, the FIR-DAC reduces the influence of clock jitter and allows the current-input CTSDM to achieve a higher SNR and linearity compared to the time-based converters.
Bilan post-retrait : les événements politiques derrière le maintien des restrictions frontalières israéliennes dans la bande de Gaza
Creators: name: Richard, Christina
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Israël
Gaza
retrait de Gaza
conflit israélo-palestinien
guerre de Gaza
Palestine
frontières

description: Le conflit israélo-palestinien constitue l’un des thèmes les plus abordés par les chercheurs de plusieurs disciplines en sciences sociales et humaines. Cette thèse s’intéresse toutefois plus particulièrement à l’effet des restrictions frontalières israéliennes dans les territoires palestiniens. Afin de comprendre quels éléments mèneraient à un assouplissement de ces restrictions, il convient de s’interroger, en continuité avec les analyses de politique étrangère associées à la théorie libérale des Relations internationales, sur les multiples motivations (et à plusieurs niveaux) de l’État hébreu à imposer ces restrictions. Il sera d’ailleurs démontré, dans un premier temps, qu’Israël a conservé le contrôle, entre le retrait de Gaza et la guerre de Gaza, sur ses frontières limitrophes à ce territoire et, dans un deuxième temps, que ce sont des considérations sécuritaires, liées au niveau de violence palestinienne et à la détérioration de la relation diplomatique officielle entre Israël et l’Autorité Palestinienne, qui ont incité Israël à exercer cette prérogative.
Supplementary document for Beyond critical coupling enhanced absorption in 2D materials based on metamaterials - 5119495.pdf
Creators: name: Guo, Shangkun
name: Deng, Jie
name: Zhou, Jing
name: Yu, Yu
name: Bu, Yonghao
name: Zhu, Tianyun
name: Ren, Xiansong
name: Li, Zhifeng
name: Lu, Wei
name: Chen, Xiaoshuang
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1 (Sec.1; Sec.2; Sec.3; Sec.4; Sec.5; Sec.6; Sec.7)
La desnudez de espíritu. Henríquez Ureña de-creator
La desnudez de espíritu. Henríquez Ureña de-creator
Creators: name: Antelo, Raúl
Publisher: name: Dipartimento di Lingue e Letterature Straniere Moderne, Università di Bologna
Year: 2009

description: The most common metaphor  to describe Henriquez Ureña pretend to  see him as a father, a creator, a founder. On the contrary here he will be  considered as a de-creator. In fact all Henríquez Ureña’s cartographying effort  can be reduced to the preoccupation to give substance to an elusive object  (Hispanoamerican Literature) througwhich it has been considered before.
description: The most common metaphor  to describe Henriquez Ureña pretend to  see  him as a father, a creator, a founder. On the contrary here he will be   considered as a de-creator. In fact all Henríquez Ureña’s cartographying  effort  can be reduced to the preoccupation to give substance to an  elusive object  (Hispanoamerican Literature) througwhich it has been  considered before.
description: La metáfora más socorrida por la crítica de  Henriquez Ureña lo ve como  un padre, como un creador, como un fundador.  Se tratará acá de leerlo en clave  contraria, como un de-creator ya que  todo el esfuerzo cartográfico de Henriquez  Ureña se reduce en dar  consistencia a un objeto esquivo, la literatura  hispanoamericana, por  medio del vaciamiento de la positividad con que se lo  abordaba hasta  entonces.
description: The most common metaphor  to describe Henriquez Ureña pretend to  see  him as a father, a creator, a founder. On the contrary here he will be   considered as a de-creator. In fact all Henríquez Ureña’s cartographying  effort  can be reduced to the preoccupation to give substance to an  elusive object  (Hispanoamerican Literature) througwhich it has been  considered before.
The importance of correct terminology in the cultural heritage field also according to the pair art-science
L'importanza della corretta terminologia nel settore dei beni culturali anche in relazione al binomio arte-scienza
Creators: name: Lorusso, Salvatore
Publisher: name: Dipartimento di Storie e Metodi per la Conservazione dei Beni Culturali (Di.S.Me.C.)
Year: 2001

description: The paper underlines the importance of using the correct terminology in the area of cultural heritage, with reference to official documents dealing with different aspects of restoration, conservation, maintenance, prevention and safeguard aimed at protecting and enhancing the value of interesting artefacts from a historic-artistic, archeological, archive-library, musical viewpoint. On the other hand, mention is made of the fact that, within the difficult relation between Arts and Science, these are actually two different ways of "describing the world".
Globalization and its effects on forest diversity: A case study of New Caledonia
Creators: name: Herring, Jamie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Biology, Ecology.
subject: Sociology, Social Structure and Development.
subject: Environmental Sciences.

description: In the scientific literature pertaining to the world's loss of biodiversity, an extensive amount of research has been undertaken to describe the local biological processes involved in the loss of endangered habitats. However, the social mechanisms that infringe upon these habitats and perpetuate human activities that destroy rare and endangered species has largely been ignored. This thesis is an attempt to discover the social, political and economic causes of habitat loss in the particular case of New Caledonia. Specifically, the extraction of nickel in New Caledonia was examined as a resource that has been central to the island's development history and which has been the cause of the most forest damage. Globalization theory and World-Systems theory have been used in a complementary way to provide a framework for how the integration of New Caledonia into the global economic system over the past 150 years has impacted the island's rare forest systems. Periods of globalization prior to the 1970's were found to have had the most destructive impact on forest habitat than the years following 1975. Greater ecological protections implemented as a result of pressures on France from both global and local environmental groups were found to have increased protection measures for the various forest habitats. However, the destruction of the forests of New Caledonia continues and strong ecological protections that would guarantee the forest's long-term health are still missing.
Cigarette smoke exposure as a potential risk factor for sleep problems in pregnant women - supplementary materials 1
Creators: name: Ciochoń, Aleksandra
name: Balwicki, Łukasz
name: Klimek, Magdalena
name: Danel, Dariusz P.
name: Apanasewicz-Grzegorczyk, Anna
name: Ziomkiewicz, Anna
name: Galbarczyk, Andrzej
name: Marcinkowska, Urszula Maria
Publisher: name: Zenodo
Year: 2024

description: Abstract

Cigarette smoking and exposure to cigarette smoke during pregnancy have detrimental effects on the health of expectant mothers, increasing the likelihood of respiratory diseases or infections. Due to the stimulant effect of smoking, the negative effect on diurnal rhythm and sleep is also observed. Sleep quantity and quality are directly related to health and well-being, especially during times of excess stress, such as the perinatal period. This prospective study aimed to examine the relationship between cigarette smoking and exposure to cigarette smoke during pregnancy and sleep patterns in pregnant women. An online survey was conducted among Polish women from May 2020 to September 2021, during the COVID-19 pandemic. Participants reported the use of stimulants during pregnancy and rated sleep in three categories (difficulty falling asleep, waking up too early, and difficulty staying asleep). Data from 3365 mothers aged 18-43 (mean 30.7; SD 3.87) were analyzed using multivariate logistic regression. The incidence of sleep problems in pregnant women was shown to be associated with exposure to cigarette smoke (passive smoking) while controlling for a range of individual variables (age, education, place of residence, satisfaction with the woman's life, and economic situation, pregnancy complications, levels of state anxiety and depressive symptoms, trimester of pregnancy, nausea or vomiting during pregnancy, and COVID-19 infections). Interestingly, active smoking was not associated with sleep difficulties. Our results suggest that passive smoking is a potential risk factor for sleeping problems in pregnant women, especially in the aspect of waking up too early. These results are worth considering when formulating pro-health measures for pregnant women and their close ones.
Female varsity athletes' perception of how coaches influence their self-confidence
Creators: name: McCharles, Beth L
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Women's Studies.
subject: Education, Physical.
subject: Health Sciences, Recreation.
subject: Recreation.

description: Communities and athletes see coaches generally as leaders, mentors, and role models in sport. Recent research in the field of coaching revealed that coaches must have the ability to encourage, challenge, and understand the athlete (Bloom, 2002b). Further research indicates that females are known to be psychologically and physically different than males (Fasting & Pfister, 2000); therefore, most females need to be coached differently than men during practice and competition. The notion of self-confidence is an essential element in Vealey's (1986) Sport Confidence Model, in which it is defined as: "the belief or degree of certainty individuals possess about their abilities to be successful in sport" (p. 222). The purpose of this qualitative study was to understand female varsity athlete's perception of how coaches influence their self-confidence. The study used twelve participants (N = 12) among Canadian Interuniversity Sport teams: basketball (3), soccer (3), hockey (2), rugby (2), and volleyball (2). Semi-structured interviews were conducted regarding athletes perception of (a) athlete's perception of self-confidence, (b) different coaching qualities that may positively or negatively influence athletes self-confidence, and (c) athletes perception of an 'ideal' coach that positively influences their self-confidence. The results displayed a combined definition of all 12 athlete's perception of self-confidence, which is "one who believes in herself, has inner strength (while not worrying about others beliefs), and stays positive throughout their sport and life." Secondly the results found four main qualities that athletes perceive essential for a coach to positively influence their self-confidence. Finally, the results revealed 12 predominant coaching characteristics that athletes perceive essential for positively influence their self-confidence. An 'ideal coach' would display these characteristics.
Entre o centro e a favela: o corpo
Creators: name: Cera, Flávia
Publisher: name: Dipartimento di Lingue e Letterature Straniere Moderne, Università di Bologna
Year: 2009

description: Slavoj Zizek, writing about May 1968, postulates, as a left-wing task, the
radicalization of the antagonism between included and excluded citizens, as well as the politization of slug (“favela”) populations. The goal of this paper is to show that a different configuration of contemporary borders, opposed to Zizek’s, can be drawn reading  Hélio Oiticica and César Aira poetics. Both of them also have an approach to the slugs, but choosing, as strategy, to avoid the delimitation of territories, therefore showing how difficult it is to designate who is excluded and who is included. They present us a new form of politics centered in the body, a politics that has happiness as its horizon. A politics that we choose to name immanent.

Este trabalho busca apontar em Hélio Oiticica e César Aira uma nova
configuração das fronteiras do contemporâneo que vai de encontro a Slavoj Zizek que em um texto sobre Maio de 1968 postula que devemos aprofundar e evidenciar os antagonismos excluídos versus incluídos e designa como tarefa a politização da população das favelas. Oiticica e Aira também abordam a favela, mas com uma estratégia de não demarcação de territórios evidenciando a dificuldade de designar quem são excluídos e quem são incluídos. Ambos nos apresentarão uma forma de política centrada no corpo e que não perde de vista a felicidade. Uma política que chamaremos neste texto de imanente.
Frequency of Screening and SBT Technique Trial - North American Weaning Collaboration (FAST-NAWC): a protocol for a multicenter, factorial randomized trial
Creators: name: Burns, K. E. A.
name: Rizvi, Leena
name: Cook, Deborah J.
name: Seely, Andrew J. E.
name: Rochwerg, Bram
name: Lamontagne, Francois
name: Devlin, John W.
name: Dodek, Peter M.
name: Mayette, Michael
name: Tanios, Maged
name: Gouskos, Audrey
name: Kay, Phyllis
name: Mitchell, Susan
name: Kiedrowski, Kenneth C.
name: Hill, Nicholas S.
Publisher: name: BioMed Central
Year: 2019

description: Rationale: In critically ill patients receiving invasive mechanical ventilation (MV), research supports the use of daily screening to identify patients who are ready to undergo a spontaneous breathing trial (SBT) followed by conduct of an SBT. However, once daily (OD) screening is poorly aligned with the continuous care provided in most intensive care units (ICUs) and the best SBT technique for clinicians to use remains controversial. Objectives: To identify the optimal screening frequency and SBT technique to wean critically ill adults in the ICU. Methods: We aim to conduct a multicenter, factorial design randomized controlled trial with concealed allocation, comparing the effect of both screening frequency (once versus at least twice daily [ALTD]) and SBT technique (Pressure Support [PS] + Positive End-Expiratory Pressure [PEEP] vs T-piece) on the time to successful extubation (primary outcome) in 760 critically ill adults who are invasively ventilated for at least 24 h in 20 North American ICUs. In the OD arm, respiratory therapists (RTs) will screen study patients between 06:00 and 08:00 h. In the ALTD arm, patients will be screened at least twice daily between 06:00 and 08:00 h and between 13:00 and 15:00 h with additional screens permitted at the clinician’s discretion. When the SBT screen is passed, an SBT will be conducted using the assigned technique (PS + PEEP or T-piece). We will follow patients until successful extubation, death, ICU discharge, or until day 60 after randomization. We will contact patients or their surrogates six months after randomization to assess health-related quality of life and functional status. Relevance: The around-the-clock availability of RTs in North American ICUs presents an important opportunity to identify the optimal SBT screening frequency and SBT technique to minimize patients’ exposure to invasive ventilation and ventilator-related complications. Trial registration: Clinical Trials.gov, NCT02399267 . Registered on Nov 21, 2016 first registered.
Estimating the privacy of quantum-random numbers
Creators: name: Seiler, Johannes
name: Strohm, Thomas
name: Schleich, Wolfgang P.
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Quantum random number generators
subject: Entanglement
subject: Quantum information
subject: DDC 530 / Physics
subject: DDC 620 / Engineering & allied operations
subject: Random number generators
subject: Quanteninformation

description: We analyze the information an attacker can obtain on the numbers generated by a user by measurements on a subsystem of a system consisting of two entangled two-level systems. The attacker and the user make measurements on their respective subsystems, only. Already the knowledge of the density matrix of the subsystem of the user completely determines the upper bound on the information accessible to the attacker.We compare and contrast this information to the appropriate bounds provided by quantum state discrimination.
Supplementary document for Controllable continuous variable quantum state distributor - 5119763.pdf
Creators: name: Wang, Qingwei
name: Wang, Yajun
name: sun, xiaocong
name: tian, yuhang
name: li, wei
name: Tian, Long
name: Yu, Xudong
name: Zhang, Jing
name: Zheng, Yaohui
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Quantum Optics

description: Supplemental document
title: Soft Machinery
Creators: name: Sayti, Chelsi
Publisher: name: University of Nevada, Las Vegas
Year: 2020

description: The following manuscript, “Soft Machinery”, serves as an creative autobiographical narrative account of the author’s marital separation and subsequent exploration of the feminine, family, and geographical place. The piece functions together as a narrative whole, with prose poems working as connective tissue between shorter form, traditional poems. While “Soft Machinery” does form around plot beats, the individual poems play into and against linear narrative in their organization and form, creating a loose story structure that imitates the thematic recurrence of memory, loss, and momentary focus in the piece. Intimate, playful moments of relational vulnerability constrict and expand alongside expressions of grief and staleness through the lens of the body. These moments, in their organization, attempt a sort of joyous whiplash while developing an emotional wholeness in the piece through their display of conflicting yet coexisting feelings. Addiction, separation, generational and cyclical family suffering, happen simultaneously with revelry, burgeoning friendship, sexuality and self discovery. Landscape is shaped by emotion and emotion by landscape. The inclusion of translation speaks to place as well, tying moments to geography and broadening scope. The title of the manuscript, “Soft Machinery” wants to reflect the ways the body, feeling, and place work sinuously in developing narrative and personal history. This work will see further development with multimodal, visual and found-text inclusions in order to bring the content to intimate life.
Improved SQNR and MSA in incremental delta sigma modulators by using a recuperation phase
Creators: name: Vogelmann, Patrick
name: Wagner, Johannes
name: Hänsler, Adrian
name: Ortmanns, Maurits
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: Incremental
subject: Sigma-delta
subject: Delta-sigma
subject: Recuperation phase
subject: DDC 620 / Engineering & allied operations
subject: Modulators (Electronics)
subject: Inkrementelles Lernen
subject: CMOS

description: This brief presents a system-level technique that is capable of enhancing the efficiency of high-resolution incremental delta sigma (I-ΔΣ) modulators. With little additional effort in circuitry it is possible to make use of a recuperation phase, in which the I-ΔΣ modulator's input is periodically tied to a defined reference. In these phases, the modulator is given time to adjust its residual error to a minimum. This method is capable of increasing the maximum stable amplitude as well as the signal-to-quantization-noise ratio. Thus, this technique is especially valuable for high-resolution ADCs employing higher order modulators, as an increase in these measures directly affects power requirements. The method is analytically derived and exemplarily simulated. Furthermore, a circuit-level simulation in a 180-nm CMOS technology is presented to validate the results.
21 year timing of the black-widow pulsar J2051-0827
Creators: name: Shaifullah, G.
name: Verbiest, J. P. W.
name: Freire, P. C. C.
name: Tauris, T. M.
name: Wex, N.
name: Oslowski, S.
name: Stappers, B. W.
name: Bassa, C. G.
name: Caballero, R. N.
name: Champion, D. J.
name: Cognard, I.
name: Desvignes, G.
name: Graikou, E.
name: Guillemot, L.
name: Janssen, G. H.
name: Jessner, A.
name: Jordan, C.
name: Karuppusamy, R.
name: Kramer, M.
name: Lazaridis, K.
name: Lazarus, P.
name: Lyne, A. G.
name: McKee, J. W.
name: Perrodin, D.
name: Possenti, A.
name: Tiburzi, C.
Publisher: name: Swinburne
Year: 2024

description: Timing results for the black-widow pulsar J2051−0827 are presented, using a 21 year data set from four European Pulsar Timing Array telescopes and the Parkes radio telescope. This data set, which is the longest published to date for a black-widow system, allows for an improved analysis that addresses previously unknown biases. While secular variations, as identified in previous analyses, are recovered, short-term variations are detected for the first time. Concurrently, a significant decrease of ∼ 2.5 × 10− 3 cm− 3 pc in the dispersion measure associated with PSR J2051−0827 is measured for the first time and improvements are also made to estimates of the proper motion. Finally, PSR J2051−0827 is shown to have entered a relatively stable state suggesting the possibility of its eventual inclusion in pulsar timing arrays.
Protein binding partners of dysregulated miRNAs in Parkinson’s disease serum
Creators: name: Ruf, Wolfgang P.
name: Freischmidt, Axel
name: Grozdanov, Veselin
name: Roth, Valerie
name: Brockmann, Sarah J.
name: Mollenhauer, Brit
name: Martin, Dorothea
name: Haslinger, Bernhard
name: Fundel-Clemens, Katrin
name: Otto, Markus
name: Arnim, Christine Von
name: Holzmann, Karlheinz
name: Ludolph, Albert C.
name: Weishaupt, Jochen H.
name: Danzer, Karin M.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Parkinson’s disease
subject: miRNA
subject: DDC 610 / Medicine & health
subject: Parkinson disease
subject: MicroRNAs
subject: Serum
subject: Parkinson-Krankheit
subject: miRNS

description: Accumulating evidence suggests that microRNAs (miRNAs) are a contributing factor to neurodegenerative diseases. Although altered miRNA profiles in serum or plasma have been reported for several neurodegenerative diseases, little is known about the interaction between dysregulated miRNAs and their protein binding partners. We found significant alterations of the miRNA abundance pattern in serum and in isolated serum-derived extracellular vesicles of Parkinson’s disease (PD) patients. The differential expression of miRNA in PD patients was more robust in serum than in isolated extracellular vesicles and could separate PD patients from healthy controls in an unsupervised approach to a high degree. We identified a novel protein interaction partner for the strongly dysregulated hsa-mir-4745-5p. Our study provides further evidence for the involvement of miRNAs and HNF4a in PD. The demonstration that miRNA-protein binding might mediate the pathologic effects of HNF4a both by direct binding to it and by binding to proteins regulated by it suggests a complex role for miRNAs in pathology beyond the dysregulation of transcription.
Bimanual coordination in Huntington's disease and Parkinson's disease
Creators: name: Gonsalves, Crystal
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Health Sciences, Recreation.
subject: Biology, Physiology.

description: Special populations that suffer from Parkinson's disease (PD) and Huntington's disease (HD) display poorer performance in movement and bimanual coordination tasks. Both PD and HD are basal ganglia disorders with neuropathology distinct from one another. The production of internally guided movements is disrupted in PD and HD, therefore utilization of the external pathway may be able to stabilize movements for these groups. The current study examines the effect of auditory cueing for these two populations in timing performance. A total of 10 PD patients, 10 healthy controls (matched for age and gender) and 2 HD patients were examined on a repetitive bimanual finger tapping task. PD patients and healthy controls were asked to perform finger tapping at two different frequencies (1.0 Hz, 2.0 Hz) and two movement types (in-phase, anti-phase). Additionally half of the trials were performed with an external cue (metronome beat), while the other half were not (cue was turned off after 10 metronome heats). Results showed that PD patients were able to effectively use the cue to facilitate bimanual coordination as it was shown that absolute mean timing errors were decreased during the cue trials. PD patients were able to perform both movement types although the more complex mirror asymmetrical anti-phase trials were more difficult to perform. HD patients were not able to achieve the designated fast and slow frequencies that PD and healthy controls performed. The HD patients' movement was highly variable due to tremors and involuntary tics experienced by the patients. Through the examination of raw trajectories and polar plots of phase differences it was concluded that the external cue did not seem to stabilize bimanual coordination for the HD patients.
Family members' experiences of living with a traumatically head-injured person: An empirical-phenomenological study.
Creators: name: Clark, Elaine Leslie.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Psychology, Social.

description: Significant improvements in medical and neurosurgical interventions have resulted in a substantial increase in the number of persons surviving traumatic head injury. Consequently, more survivors and their families find themselves having to learn to cope and live with the impairments that accompany head injury. While the nature and degree of recovery is often difficult to pre-determine, most individuals require a comprehensive spectrum of medical, rehabilitative and supportive services to facilitate and maintain the recovery process. The complex nature of family life involving shared living-space, time and history, and the multiplicity of sequelae which impact on family life following traumatic head injury, challenge traditional research methods. In response, recent research studies, which centre on the alterations to family life following head injury, have endeavoured to include qualitative dimensions along with quantitative measures in order to provide a more comprehensive picture of the difficulties faced by families. These studies also fall short of investigating the deeper dimensions of family life, namely the intersubjective realm. Using an existential-phenomenological research approach, we have undertaken an indepth investigation of one family whose young adult son sustained a traumatic head injury resulting in severe impairment including loss of communication and movement. Applying an adapted version of Giorgi's systematized phenomenological method, our investigation revealed a temporal unfolding of three phases through which the family moved in its experience of living with a traumatically head-injured person: a pre-accident life-world, a phase of living with the immediate experience of the accident and a readjusting phase where family members worked to recreate and regain a sense of familial wholeness. As well, the disruption and disconnection experienced by family members following the accident was shown to originate from a deeper disruption at the foundational level of human existence. The structural matrix of themes that constituted our research family's life-world following this tragic accident was dominated by the themes of brokenness and disconnection, a restricted life-world, a disparity between inner and outer family life and a call to care. The Heideggerian theme of care was the family's existential response to the "broken" existence and near loss of their family member. It emerged as the underlying theme which held together and guided the reconfigured familial structure.
Molecular analysis of Simpson-Golabi-Behmel syndrome: An overgrowth condition associated with an increased risk of embryonal tumour.
Creators: name: Xuan, Jian Ying.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Biology, Genetics.

description: Genetic linkage analysis of two Simpson-Golabi-Behmel syndrome families in our lab has been conducted. The closest linkage to SGBS was observed for the chromosome Xq26 locus HPRT. SGBS-Xq marker recombinations map the disease locus to the Xqcen-DXS425-SGBS-DXS1123-Xqter interval on Xq25-q27. The close linkage between the disease locus and the HPRT locus strongly suggests that the causative gene for SGBS is located in the chromosome Xq26 region and is disrupted by the translocation. SGBS shows significant clinical overlap with another overgrowth disorder called Beckwith-Wiedemann syndrome (BWS). Both disorders demonstrate an increased risk for developing embryonal tumours. Two genes from the BWS linked chromosome 11p15 region, IGF2 and H19, are known to normally undergo parental imprinting. Relaxation of this imprinting has recently been demonstrated in some BWS cases as well as in some instances of isolated Wilms' tumour (WT). Since SGBS and BWS have been postulated to result from distinct defects in a common pathway, we have studied the methylation pattern and transcriptional activity of IGF2 and H19 in isolated SGBS +/$-$WT tissue. No consistent methylation abnormalities were observed in genomic DNA isolated from SGBS leucocytes, placenta, skin fibroblasts or cleft lip tissues. Genotyping of H19 cDNA polymorphisms showed biallelic expression in both SGBS and normal placentas and monoallelic expression in one SGBS fibroblast. However monoallelic expression of IGF2 was seen in control placenta and fibroblast but biallelic expression of IGF2 was shown in one SGBS placenta, and two SGBS fibroblasts tissues. It would thus appear that loss of genomic imprinting may play a role in the pathogenesis of SGBS. This is the first example that we are aware of a trans imprinting function for a human gene. (Abstract shortened by UMI.)
Nutrition for the ageing brain: Towards evidence for an optimal diet
Creators: name: Vauzour, David
name: Camprubi-Robles, Maria
name: Miquel-Kergoat, Sophie
name: Andres-Lacueva, Cristina
name: Banati, Diana
name: Barberger-Gateau, Pascale
name: Bowman, Gene L.
name: Caberlotto, Laura
name: Clarke, Robert
name: Hogervorst, Eef
name: Kiliaan, Amanda J.
name: Lucca, Ugo
name: Manach, Claudine
name: Minihane, Anne-Marie
name: Mitchell, Ellen Siobhan
name: Perneczky, Robert
name: Perry, Hugh
name: Roussel, Anne-Marie
name: Schuermans, Jeroen
name: Sijben, John
name: Spencer, Jeremy P. E.
name: Thuret, Sandrine
name: van de Rest, Ondine
name: Vandewoude, Maurits
name: Wesnes, Keith
name: Williams, Robert J.
name: Williams, Robin S. B.
name: Ramirez, Maria
Publisher: name: Swinburne
Year: 2024

description: As people age they become increasingly susceptible to chronic and extremely debilitating brain diseases. The precise cause of the neuronal degeneration underlying these disorders, and indeed normal brain ageing remains however elusive. Considering the limits of existing preventive methods, there is a desire to develop effective and safe strategies. Growing preclinical and clinical research in healthy individuals or at the early stage of cognitive decline has demonstrated the beneficial impact of nutrition on cognitive functions. The present review is the most recent in a series produced by the Nutrition and Mental Performance Task Force under the auspice of the International Life Sciences Institute Europe (ILSI Europe). The latest scientific advances specific to how dietary nutrients and non-nutrient may affect cognitive ageing are presented. Furthermore, several key points related to mechanisms contributing to brain ageing, pathological conditions affecting brain function, and brain biomarkers are also discussed. Overall, findings are inconsistent and fragmented and more research is warranted to determine the underlying mechanisms and to establish dose-response relationships for optimal brain maintenance in different population subgroups. Such approaches are likely to provide the necessary evidence to develop research portfolios that will inform about new dietary recommendations on how to prevent cognitive decline.
Alcoholism treatment digest (Release No. 67, December 16, 1963)
Creators: name: Keller, Mark
Publisher: name: No Publisher Supplied
Year: 1963

description: The Alcoholism Treatment Digest was a subscription-based publication prepared for special clients by the editorial department of the Quarterly Journal of Studies on Alcohol / Journal of Studies on Alcohol from 1950 to 1973 with Mark Keller as editor. It was published in February, April, June, October, and December, summarizing scholarly content on four topics, available to republish with attribution. Some of the reviews were simultaneously published in the "Connecticut Review on Alcoholism" under the identical subtitle "Alcoholism Treatment Digest" every other month. The authors of the reviews were first noted in 1964, in the June issue.Contents, Release No. 671.Disulfiram Therapy: Chemical Fence or Trap? ·2.Complex Treatment of Alcoholism3.The Children of Alcoholics4.When Alcoholism is Masked
L'annonce de la Bonne Nouvelle de Dieu : une analyse de la figure narrative de Dieu dans les discours pétriniens d'évangélisation des Actes des Apôtres (Ac 2,14-40 ; 3,12-26 ; 4,8-12 ; 5,29-32 et 10,34-43).
Creators: name: Dionne, Christian.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Religion, Biblical Studies.

description: Les études sur les discours d'évangélisation des Actes des Apôtres sont nombreuses. La théo-logie des discours n'a pas bénéficié d'un traitement comparable à celui qu'a reçu, par exemple, la christologie des discours. Tout en reconnaissant que Jésus Christ occupe effectivement une place importante dans ces annonces de la Bonne Nouvelle faites aux Juifs, il nous est apparu qu'on avait négligé la place et la fonction que Dieu tient dans ces discours. Tout au long de notre travail, nous avons, en effet, voulu montrer que la théo-logie des discours constitue une composante essentielle de l'annonce de la Bonne Nouvelle adressée aux Juifs. En somme, il s'agissait de nous interroger sur la figure narrative de Dieu, afin de voir comment cette figure était caractérisée dans les discours de Pierre et quelle fonction elle jouait à l'intérieur de ces discours. Quod erat demonstrandum . Afin de vérifier cette hypothèse, nous avons opté pour une démarche en deux temps. Premièrement, l'étude des cinq discours pétriniens d'évangélisation a été faite. Secondement, nous avons repris dans un dernier chapitre l'ensemble des résultats obtenus au cours des analyses particulières afin de dégager un portrait global du Dieu des discours pétriniens d'évangélisation. Parmi les diverses approches mises à notre disposition par l'exégèse scientifique, nous avons choisi de demeurer dans une perspective résolument synchronique et littéraire. Il est apparu que Dieu est un personnage omniprésent que le lecteur rencontre dans tous les discours de Pierre, sans exception. Deuxièmement, nous avons montré que la manière dont Pierre parle de Dieu dans les discours épouse parfaitement la forme narrative. Troisièmement, Dieu se présente essentiellement comme un personnage qui entre en relation avec d'autres personnages (les Apôtres, les prophètes, Israël, etc.) et, au premier chef, avec Jésus de Nazareth. Quatrièmement, à partir des relations que Dieu entretient avec d'autres personnages, nous avons pu déduire un autre trait de la figure narrative de Dieu, à savoir: sa discrétion. Cinquièmement, si le Dieu à propos duquel Pierre s'exprime n'est pas, pour l'essentiel, un Dieu différent de celui dont il est question dans le Premier Testament--Pierre parle à propos du Dieu d'Israël--il n'en demeure pas moins que l'Apôtre annonce certains traits nouveaux qui sont inconnus de ses auditeurs. En conclusion, notre recherche a permis de montrer que la figure narrative de Dieu est bien présente dans les discours pétriniens d'évangélisation et que l'action de cette figure narrative tient une place fondamentale dans ces discours. (Abstract shortened by UMI.)
The ongoing Judaisation of the Naqab and the struggle for recognising the Indigenous rights of the Arab Bedouin people
Creators: name: Nasasra, Mansour
Publisher: name: Swinburne
Year: 2024

description: This paper argues that there is a current and renewed escalation in Israeli policies towards the indigenous Bedouin of the Naqab and Beersheba, and that this escalation emerges from two longstanding, fundamental Israeli aims: Judaising the Naqab; and putting an end to the persistent Bedouin claims to their historical land and rights. The repeated demolition of the village of Al-Araqib on July 2010 is just the latest outstanding example of the Israeli policies of Judaising the Naqab and denying Bedouin land claims and historical rights. Israel appears to be pursing an ultimate solution to the demographic concern of the Bedouin in the Naqab by bringing more settlers into the area, and expelling the majority of the Bedouin of the unrecognised villages to live in urban towns.
Supplementary document for Transient absorption with tunable excitation pump reveals the color center’s photocycle in wide bandgap solids - 5120154.pdf
Creators: name: De Michele, Vincenzo
name: sciortino, Alice
name: Messina, Fabrizio
name: Cannas, Marco
name: Boukenter, Aziz
name: Marin, Emmanuel
name: Girard, Sylvain
name: Ouerdane, Youcef
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Nonlinear Optics and Spectroscopy

description: Supplemental document
YAVA: Yet Another Vegan App
Creators: name: Haupenthal, Yannic
Publisher: name: figshare
Year: 2020
Subjects: subject: 80306 Open Software
subject: FOS: Computer and information sciences
subject: 80505 Web Technologies (excl. Web Search)
subject: 80709 Social and Community Informatics
subject: FOS: Media and communications
subject: 80107 Natural Language Processing
subject: 80502 Mobile Technologies
subject: 80699 Information Systems not elsewhere classified

description: Bei vegan lebenden Menschen ist es gerade in der Anfangszeit, nachdem die Entscheidung getroffen wurde von nun an vegan zu leben, schwierig, sich im Supermarkt zurechtzufinden, da ausgiebig die Inhaltsstoffe aller zu konsumierenden Produkte genaustens studiert werden müssen. Und auch nach diesem Studium kann es immer noch sein, dass das Produkt nicht vegan ist, da etwa tierische Stoffe in der Herstellung benutzt wurden, die allerdings nicht deklariert werden müssen. Um dies zu klären sind üblicherweise Produktanfragen an den*die Hersteller*in von Nöten oder eine vorherige Recherche im Internet, sofern nicht auf dem Produkt explizit angegeben wurde, dass es vegan ist oder es durch gewisse Zutaten unvegan ist. Auch die verwandten Arbeiten, die in dieser Arbeit betrachtet werden, lösen diese Probleme nicht, da sie nicht oder nur teilweise über vegane Daten verfügen und wenn, diese nicht mit Produktanfragen oder ähnlichen Quellen belegt sind. Diese Daten sind auch nicht lizenzfrei, d. h. zur freien Benutzung verfügbar. Daher wird in dieser Arbeit eine lizenzfreie Produktdatenbank mit dem Namen "YAVA: Yet Another Vegan App" vorgestellt, die automatisch nach der Eintragung eines Produktes die Veganität, d. h. ob und wie ein Produkt vegan ist, aus den Zutateninformationen berechnen bzw. die Veganität durch Produktanfragen und Kommentaren belegen kann. Die Produktanfragen können dazu dynamisch generiert und an die Hersteller*innen versendet werden. Durch die mobile App, die im Supermarkt dazu verwendet werden kann, ein Produkt anhand des Barcodes auf die Veganität hin zu überprüfen, und der Datenbank im Hintergrund wird das Problem gelöst, welches am Anfang beschrieben wurde. Im letzten Teil dieser Arbeit wird beschrieben, wie auf der Basis dieser Arbeit andere Arbeiten aufgebaut werden können bzw. wie YAVA erweitert werden kann.