cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Predicting response rate: a natural experiment : note
Creators: name: Axhausen, Kay W.
Publisher: name: ETH Zurich
Year: 2007
Subjects: STICHPROBENERHEBUNG (MATHEMATISCHE STATISTIK)
DATA COLLECTION (MATHEMATICAL STATISTICS)
DATENERHEBUNG (MATHEMATISCHE STATISTIK)
TRANSPORT STATISTICS + TRAFFIC CENSUS (TRANSPORTATION AND TRAFFIC)
VERKEHRSSTATISTIK + VERKEHRSZÄHLUNG (VERKEHR UND TRANSPORT)
QUESTIONNAIRES (MATHEMATICAL STATISTICS)
info:eu-repo/classification/ddc/380
Commerce, communications, transport

description: Arbeitsberichte Verkehrs- und Raumplanung, 434
Tageszeitliche Fahrtenmatrizen im Personenverkehr an Werktagen im Jahr 2000: Endbericht
Creators: name: Vrtic, Milenko
name: Schüssler, Nadine
name: Erath, Alex
name: Meister, Konrad
name: Axhausen, Kay W.
Publisher: name: ETH Zurich
Year: 2007
Subjects: subject: TRAVEL DEMAND (TRANSPORTATION AND TRAFFIC)
subject: PASSENGER TRANSPORT (TRANSPORTATION AND TRAFFIC)
subject: TRAFFIC ANALYSIS (TRANSPORTATION AND TRAFFIC)
subject: VERKEHRSNACHFRAGE (VERKEHR UND TRANSPORT)
subject: PERSONENVERKEHR (VERKEHR UND TRANSPORT)
subject: VERKEHRSANALYSE (VERKEHR UND TRANSPORT)
subject: info:eu-repo/classification/ddc/624
subject: info:eu-repo/classification/ddc/380
subject: Civil engineering
subject: FOS: Civil engineering
subject: Commerce, communications, transport

description: Arbeitsberichte Verkehrs- und Raumplanung, 459
Dominance variables and intervening opportunities for choice set generation
Creators: name: Cascetta, Ennio
name: Pagliara, Francesca
name: Axhausen, Kay W.
Publisher: name: ETH Zurich
Year: 2007
Subjects: spatial choices
GEOMETRISCHES SCHLIESSEN + RÄUMLICHES SCHLIESSEN (KÜNSTLICHE INTELLIGENZ)
dominance variables
GEOMETRIC REASONING + SPATIAL REASONING (ARTIFICIAL INTELLIGENCE)
Choice set
sampling techniques
random utility models
info:eu-repo/classification/ddc/004
Data processing, computer science

description: Working Paper / IVT, 474
title: Το πιστοποιητικό συστημάτων περιβαλλοντικής διαχείρισης, ISO14001 και η εφαρμογή του στην Πλάστικα Κρήτης ΑΕ
Creators: name: Μακρυλάκης Δημήτρης
Publisher: name: Technical University of Crete
Year: 1998

description: Μη διαθέσιμο
title: Αποτελεσματικότητα και ασφάλεια της κατανάλωσης εκχυλίσματος ρυζιού κόκκινης ζύμωσης σε ανθρώπους με υπερχοληστερολαιμία. Συστηματική ανασκόπηση και μετα-ανάλυση
title: Effectiveness and efficacy of red yeast rice consumption in humans with hypercholesterolemia. Systematic review and meta-analysis
titleType: AlternativeTitle
Creators: name: Τρογκάνης, Ευστράτιος
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2022
Subjects: Κόκκινο ρύζι
Υπερχοληστερολαιμία
Συστηματική ανασκόπηση
Μετα-ανάλυση
Τροφοφάρμακα

description: Σκοπός: Σκοπός της παρούσας μελέτης είναι η διερεύνηση της ασφάλειας και της αποτελεσματικότητας της κατανάλωσης ενός τροφοφαρμάκου, του εκχυλίσματος ρυζιού κόκκινης ζύμωσης (Red yeast rice extract), ως προς τη μείωση της υπερχοληστερολαιμίας σε ανθρώπους. Μεθοδολογία: Πραγματοποιήθηκε συστηματική ανασκόπηση και μετα-ανάλυση, με αναζήτηση άρθρων από τις βάσεις δεδομένων PubMed, Cochrane Central Register of Clinical Trials (CENTRAL), Excerpta Medica Database (Embase), Scopus, CINAHL και Clinicaltrials.gov με βάση τη μεθοδολογία PRISMA. Η αναζήτηση των μελετών αφορούσε την περίοδο από τον Ιανουάριο του 2012 μέχρι τον Μάιο του 2022. Αποτελέσματα: Στη μελέτη συμπεριλήφθηκαν 14 κλινικές δοκιμές. Οι παρεμβάσεις διήρκησαν από 4-24 εβδομάδες. Στις περισσότερες μελέτες υπήρχε 1 ομάδα παρέμβασης και 1 ομάδα ελέγχου. Ως προς την αποτελεσματικότητα, στις μελέτες που ανασκοπήθηκαν, τα σκευάσματα με Red Yeast Rice extract, φαίνονται να συμβάλλουν στατιστικά σημαντικά κυρίως στη μείωση της ολικής χοληστερόλης (μείωση 37.43mg/dl, 95% CI -47.08, -27.79) και της LDL-C (μείωση 35.82mg/dl, 95% CI -43.36, -28.29), χωρίς να επηρεάζουν τις παραμέτρους HDL-C, TGs, ApoA-I, Apo-B. Ως προς την ασφάλεια, στις μελέτες που ανασκοπήθηκαν, βρέθηκε ότι το συγκεκριμένο τροφοφάρμακο παρουσιάζει σπάνιες και μη απειλητικές για τη ζωή ανεπιθύμητες ενέργειες. Συμπεράσματα: Η κατανάλωση του εκχυλίσματος ρυζιού κόκκινης ζύμωσης από ανθρώπους με υπερχοληστερολαιμία σχετίζεται στατιστικά σημαντικά με την μείωση της ολικής χοληστερόλης και της χαμηλής πυκνότητας χοληστερόλης, ενώ δεν σχετίζεται με απειλητικές για τη ζωή ανεπιθύμητες ενέργειες.
title: Δημιουργία και λειτουργία περιβάλλοντος εργαστηρίου CAD με βάση τα  συστήματα Pro/Engineer και Pt/Modeler
Creators: name: Μαντζαφλάρας Γιώργος
Publisher: name: Technical University of Crete
Year: 1998

description: Μη διαθέσιμο
[Zentralschulhaus in Zofingen]
Creators: name: Sprüngli, F.
Publisher: name: F. Sprüngli Photograph
Year: 1876
Subjects: Schulgebäude

description: Gemeindeschulhaus, auch Gemeindeschule genannt
description: F. Sprüngli
description: Datierung gemäss Baujahr
description: Aus der Sammlung Breitinger (1841-1913) Exemplar der Zentralbibliothek Zürich, Graphische Sammlung und Fotoarchiv
title: Ανάπτυξη και μελέτη απόδοσης αλγορίθμου εγγυημένης μετάδοσης χρονικά ευαίσθητων ροών δεδομένων σε μικροκυψελωτά ασύρματα δίκτυα
Creators: name: Καλογερίνης Νικόλαος
Publisher: name: Technical University of Crete
Year: 2002

description: Μη διαθέσιμο
Association between white matter lesions and Parkinson’s disease: an impact on Postural/Gait difficulty phenotype and cognitive performance
Creators: name: Sinani, Olga
name: Dadouli, Katerina
name: Ntellas, Panagiotis
name: Kapsalaki, Eftychia Z
name: Vlychou, Marianna
name: Raptis, Dimitrios G
name: Marogianni, Chrysoula
name: Markou, Katerina
name: Dardiotis, Efthimios
name: Xiromerisiou, Georgia
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology
subject: 60506 Virology

description: White matter hyperintensities (WMHs) may be observed on Magnetic Resonance Imaging (MRI) in patients with Parkinson disease with or without vascular risk factors. Whether WMHs may influence motor and non-motor aspects of Parkinson disease is a subject of debate. The aim of this study is to evaluate the impact of WMH severity on various aspects of Parkinson disease in combination to the estimation of the impact of cerebrovascular risk factors. We included a cohort of patients with Parkinson’s disease who underwent MRI examination. The Fazekas visual rating scale was used to assess the severity and location of WMHs, and patient clinical characteristics were correlated with MRI data. All vascular risk factors were associated with higher Fazekas score in both periventricular and deep white matter. Periventricular white matter hyperintensities (PWMHs) and deep white matter hyperintensities (DWMHs) were associated with lower scores in the ACE-R cognitive assessment scale (p < 0.001). Furthermore, PWMHs and DWMHs severity was associated with higher UPDRS motor score (p < 0.001), while the Postural Instability Gait Difficulty (PIGD) phenotype was correlated with higher burden of WMHs. Comorbid WMHs may contribute to multi-dimension dysfunction in patients with Parkinson disease and consequently the management of vascular risk factors may be crucial to maintain motor and non-motor functions in PD.
Minute book II
Creators: name: British Swiss Chamber of Commerce
Publisher: name: [s.n.]
Year: 1926

description: Darin: Register, enclosures/Beilagen
description: Handwritten
description: Englisch
description: Verzeichnung=Description=Inventaire 04.05.2022 Automatisierter Import Archivbestand
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Minute book III
Creators: name: British Swiss Chamber of Commerce
Publisher: name: [s.n.]
Year: 1940

description: Darin: Register, enclosures/Beilagen
description: Handwritten
description: Englisch
description: Verzeichnung=Description=Inventaire 04.05.2022 Automatisierter Import Archivbestand
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Briefkopierbuch
Creators: name: Passavant & Cie
Publisher: name: [s.n.]
Year: 1868

description: Enthält: Eingeklebte Briefkopien und anderweitige Einlagen vom 28.12.1868 - 31.12.1868
description: Darin: Register
description: Französisch, Deutsch
description: Verzeichnung=Description=Inventaire 2014 ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Sebastian Preher
title: Επίδοση επαναληπτικών (Turbo) κωδικών σε δίαυλο κινητών επικοινωνιών
Creators: name: Κωνσταντινίδης Κωνσταντίνος
Publisher: name: Technical University of Crete
Year: 2002

description: Μη διαθέσιμο
Additional file 5: of Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer
Creators: name: Shinde, Aparna
name: Wilmanski, Tomasz
name: Chen, Hao
name: Teegarden, Dorothy
name: Wendt, Michael
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Plant Biology

description: Figure S5. HIF-1α expression that characterizes primary tumors is lost in pulmonary metastases. 4 T1 cells were engrafted onto the mammary fat pad via an intraductal injection and grown as primary tumors. These tumors gave rise to spontaneous pulmonary metastases. Upon necropsy both primary and metastatic tumors were analyzed by immunohistochemistry for the expression of HIF-1α. Nuclear expression of HIF-1α is very high in viable primary tumor tissue. In contrast, nuclear HIF-1α is drastically reduced in pulmonary metastases. Data are representative of three separate mice bearing primary tumors and metastases. (PDF 1389 kb)
Dylan and Eva's Case Study: Planning a research use initiative
Creators: name: Gleeson, Jo
name: Cutler, Blake
name: Hall, Genevieve
name: Rickinson, Mark
name: Walsh, Lucas
Publisher: name: Monash University
Year: 2023
Subjects: Professional education and training
Teacher education and professional development of educators
Educational administration, management and leadership

description: This practitioner case study shares the story of Dylan and Eva and how they carefully planned a research-informed change at their school.
 This case study was developed by the Monash Q Project (2019-2023) and is designed for teachers, school leaders and education system actors who are using research in their work and are looking to use research evidence to support their practice.
Additional file 2 of Lower serum nicotinamide N-methyltransferase levels in patients with bipolar disorder during acute episodes compared to healthy controls: a cross-sectional study
Creators: name: Hu, Qing
name: Liu, Farong
name: Yang, Luyin
name: Fang, Zanxi
name: He, Jue
name: Wang, Wenqiang
name: You, Pan
Publisher: name: figshare
Year: 2020
Subjects: Medicine
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified

description: Additional file 2: Table S2. Numeric Results for Two-Sample T-Test Allowing Unequal Variance Alternative Hypothesis: H1: δ = μ1 - μ2 ≠ 0.
title: Μελέτη της απόδοσης του τοπικά βέλτιστου BAYES ανιχνευτή σήματος σε σχέση με ανιχνευτές που υλοποιούνται με νευρωνικά δίκτυα
Creators: name: Ζέρβας Παναγιώτης
Publisher: name: Technical University of Crete
Year: 2002

description: Μη διαθέσιμο
Critical Making in Education Manifesto
Creators: name: Kutschera, Alexander
Publisher: name: Zenodo
Year: 2023

description: The Critical Making in Education Manifesto is a poster with crucial identified statements for frame-working Critical Making in education. It is based on discussions and feedback received during six workshops in 2022. The first version was further refined after online review by the community and after feedback collecting during its exhibiting at re:publica Berlin 2023. The manifesto embodies crucial learnings for Critical Making in Education. The source files of the manifesto are on GitHub repository, allowing further discussions and edits by the community beyond the Critical Making project, so it can live on. A print-ready PDF version is shared here and via the Critical Making Website Repository: https://github.com/vektorious/critical_making_manifesto Link: https://manifesto.criticalmaking.eu
Can the Smoke-Free Ratio be a Novel Indicator of the Cardiovascular and Metabolic Risk Reduction of Former Smokers? A Cross-Sectional Study
Creators: name: dağcıoğlu, basri furkan
Publisher: name: figshare
Year: 2023
Subjects: Health promotion
Preventative health care

description: Objective: The association of smoking with many diseases is well known, as well as are the benefits of smoking cessation. While mentioning these benefits, the duration that passes after quitting smoking is always stressed. However, former smokers' history of smoking exposure is usually ignored. This study aimed to investigate the possible effect of the pack-years history on several cardiovascular health parameters. Methods: A cross-sectional study was conducted on 160 ex smoker participants. A novel index was described and named the "smoke-free ratio" (SFR), which is the number of smoke-free years divided by the number of pack-years. The associations between the SFR and various laboratory values, as well as anthropometric and vital measurements, were investigated. Results: The SFR was negatively correlated with body mass index, diastolic blood pressure, and pulse in women with diabetes. In the healthy sub-group, fasting plasma glucose was negatively and high-density lipoprotein cholesterol positively correlated with the SFR. A Mann-Whitney U test revealed that the cohort with metabolic syndrome had significantly lower SFR scores (Z = -2.11; P = .035). In binary grouping, the participants with low SFR scores had higher rates of metabolic syndrome. Discussion: This study revealed some impressive features about the SFR, which is proposed as a novel tool for estimating metabolic and cardiovascular risk reduction in former smokers. Nevertheless, the actual clinical significance of this entity remains unclear.
title: Χαρακτηρισμός της υπόγειας ροής με προσομοίωση της περιοχής του ποταμού Ασωπού, νομού Αττικής
Creators: name: Συρράκου Χριστίνα
Publisher: name: Technical University of Crete
Year: 2008

description: Μη διαθέσιμο
title: Ενεργειακή μελέτη του κτηρίου μηχανικών περιβάλλοντος με αξιοποίηση φωτοβολταϊκών στοιχείων
Creators: name: Παπαντωνίου Σωτήρης
Publisher: name: Technical University of Crete
Year: 2008

description: Μη διαθέσιμο
L'analisi delle pubblicazioni come supporto alla gestione dei contratti Read&Publish dell'INFN
Creators: name: Piergentili, Irene
Publisher: name: INFN Open Access Repository
Year: 2023
Subjects: Transformative Agreements
Gold open access
Open Access Repository
Web of Science
INFN
read&publish
corresponding author

description: Presentazione per l'evento GenOA week 2023, Biblioteche per l'Open Science (Genova, 25 ottobre 2023) Con la crescente diffusione dei contratti trasformativi diventa necessario stabilire una costante collaborazione tra le biblioteche e gli istituti di ricerca, per favorire la transizione verso la scienza aperta con costi sostenibili. In questo lavoro viene presentato uno studio di analisi delle pubblicazioni dei corresponding authors dell’INFN, al fine di supportare efficacemente la gestione dei contratti editoriali di tipo "read&publish". La ricerca è stata realizzata consultando i dati presenti in Web of Science, applicando determinati filtri di ricerca e operando un confronto con le ricerche svolte in precedenza e con le informazioni fornite da determinati editori. I dati raccolti hanno consentito all’INFN di negoziare in modo più efficace con gli editori, tenendo conto del numero delle pubblicazioni dei propri ricercatori negli anni precedenti. Verranno illustrate alcune delle problematiche riscontrate nel corso della ricerca: varianti del nome dell’ente, indicizzazione delle riviste nel database bibliografico Web of Science, affiliazioni indicate dal corresponding author. La ricerca si propone come punto di partenza per un’analisi più dettagliata delle pubblicazioni degli autori INFN, come la scelta delle sedi editoriali, le tendenze all’autoarchiviazione, l’evoluzione delle collaborazioni scientifiche, e per avviare, inoltre, un confronto tra le risorse presenti nei diversi database dell’INFN, in vista del popolamento dell’archivio istituzionale Open Access Repository. In conclusione, sarà evidenziata l’importanza dell'analisi dei dati sulle pubblicazioni scientifiche per ottimizzare la gestione dei contratti editoriali in un ente di ricerca, dando rilievo al ruolo ricoperto dalle biblioteche nelle attività di promozione della scienza aperta.
Additional file 6 of 4’-O-Methylbroussochalcone B as a novel tubulin polymerization inhibitor suppressed the proliferation and migration of acute myeloid leukaemia cells
Creators: name: Liu, Ziying
name: Wang, Changshui
name: Wang, Yali
name: Wang, Lei
name: Zhang, Yueyuan
name: Yan, Genquan
Publisher: name: figshare
Year: 2021
Subjects: Biophysics
Biochemistry
Physical Sciences not elsewhere classified
Cell Biology
Molecular Biology
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Cancer
Hematology

description: Additional file 6: Table S1. Inhibition of Tubulin Polymerization
Understanding Olympic Values and Physical Activity in the adult population of Chile and Argentina
Creators: name: Bacot, Alejandro
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2022
Subjects: subject: Ολυμπισμός
subject: Ολυμπιακό κίνημα
subject: Ολυμπιακές αξίες
subject: Ολυμπιακοί Αγώνες Νέων - Αργεντινή
subject: Olympism
subject: Olympic movement
subject: Olympic values
subject: Youth Olympic Games - Argentina
subject: olympism
subject: Olympic Values
subject: Physical Activity
subject: Moral Competence
subject: Fair Play

description: The thesis has the aim to compare and examine the level of understanding the Olympic Values in the adult population (18-65 years) in Chile (n=100) and Argentina (n=100). Argentina was recent host country of the youth Olympic Games, and Chile will be host of the Panamerican Games in 2023, so it was worth investigating what the level of understanding the Olympic Values. The survey method has been developed with the theory of Fair Play from Jim Parry and the application of the moral influence scale and Moral Competence Test MCT by George Lind. There was also carried out comparison of the level of physical activity among the two populations of adults with the use of a survey methods. With the results of the survey, and with the comparison between countries it is possible to know the level of understanding the Olympic Values in that population, the moral factors who influence in population and the physical activity statistics in those countries. The average level of moral competence of the examined Argentine adult population turned out to be higher their among similar adult population of Chile and no impact of Buenos Aires Youth Olympic games (2018) was noticed in case of Argentina. The most influential factor concerning the source of influence on the level of moral competences pointed by the two examined population of adults of Chile and Argentina appeared to be parents. In case of physical activity, the situation in both countries seems to be similar, the level of physical activity, although a little bit higher among the adults of Argentina was still insufficient in some age-related groups, while in Chile it was more diverse.
title: Experimental and CFD study of the selected acoustic helicoidal resonator as a final element of an air installation
Creators: name: Łapka, Wojciech
name: Jakubowski, Piotr
Publisher: name: Publishing House of Poznan University of Technology
Year: 2023

description: Vibrations in Physical Systems, 34(1), 2023112-1 - 2023112-8
Erasmus von Rotterdam, Apophthegmata. Herausgegeben, eingeleitet, übersetzt und mit Anmerkungen versehen von Heribert Philips
Creators: name: Lohmann, Rainer
Publisher: name: Forum Classicum
Year: 2017

description: Rezension zu: Erasmus von Rotterdam, Apophthegmata. Herausgegeben, eingeleitet, übersetzt und mit Anmerkungen versehen von Heribert Philips. Würzburg: Königshausen & Neumann 2001. 695 S. (ISBN 3-8260-2015-4).
description: Forum Classicum, Nr. 4 (2001): Forum Classicum
Nucleus basalis of Meynert predicts cognition after deep brain stimulation in Parkinson's disease
Creators: name: Kübler, Dorothee
name: Wellmann, Sophie Katharina
name: Kaminski, Jakob
name: Skowronek, Cornelia
name: Schneider, Gerd-Helge
name: Neumann, Wolf-Julian
name: Ritter, Kerstin
name: Kühn, Andrea
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Basal forebrain
subject: Cognition
subject: Deep brain stimulation
subject: Nucleus basalis of meynert
subject: Parkinson's disease
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: INTRODUCTION Subthalamic DBS in Parkinson's disease has been associated with cognitive decline in few cases. Volume reduction of the nucleus basalis of Meynert (NBM) seems to precede cognitive impairment in Parkinson's disease. In this retrospective study, we evaluated NBM volume as a predictor of cognitive outcome 1 year after subthalamic DBS. METHODS NBM volumes were calculated from preoperative MRIs using voxel-based morphometry. Cognitive outcome was defined as the relative change of MMSE or DemTect scores from pre-to 1 year postoperatively. A multiple linear regression analysis adjusted for the number of cognitive domains affected in the preoperative neuropsychological testing and UPDRS III was conducted. To account for other variables and potential non-linear effects, an additional machine learning analysis using random forests was applied. RESULTS 55 patients with Parkinson's disease (39 male, age 61.4 ± 7.5 years, disease duration 10.8 ± 4.7 years) who received bilateral subthalamic DBS electrodes at our center were included. Although overall cognition did not change significantly, individual change in cognitive abilities was variable. Cognitive outcome could be predicted based on NBM size (B = 208.98, p = 0.022*) in the regression model (F(3,49) = 2.869; R2 of 0.149; p = 0.046*). Using random forests with more variables, cognitive outcome could also be predicted (average root mean squared error between predicted and true cognitive change 11.28 ± 9.51, p = 0.039*). Also in this model, NBM volume was the most predictive variable. CONCLUSION NBM volume can be used as a simple non-invasive predictor for cognitive outcome after DBS in Parkinson's disease, especially when combined with other clinical parameters that are prognostically relevant.
Psychosocial peer mediation as sustainable method for conflict prevention and management among refugee communities in Germany
Creators: name: Winter, Helen M. E.
name: Klapprott, Felix
name: Naanaa, Muhamad
name: Turk, A. Marco
name: Winter, Sebastian F.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: alternative dispute resolution
subject: conflict management
subject: mental health literacy
subject: peer mediation
subject: refugees
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Following the arrival of over 1.2 million refugees and asylum seekers since the 2015 European refugee crisis, Germany has faced enormous humanitarian and societal challenges, with direct implications for participatory peace-building efforts at the local community level. A multitude of postmigration stressors and high prevalence of mental health conditions among refugees contribute to the substantial burden of daily conflicts in refugee shelters and communities. Ongoing exposure to a conflict-prone environment, psychological distress and stigmatization among community members can severely impair the quality of life and aggravate existing health-related, socio-economic and integrational challenges. Previous research has demonstrated the feasibility of individual alternative dispute resolution (ADR) and mental health literacy (MHL) interventions in refugee settings. As interpersonal conflict and psychological well-being constitute mutually interdependent phenomena, integrated methodologies combining ADR with MHL may offer unique value to affected vulnerable populations. However, systemic implementation of such mechanisms in refugee shelters has remained largely unexplored. In recognition of this unmet need and as part of the nonprofit organization R3SOLUTE, we have developed a tailored educational curriculum directed at equipping refugees in shelters and their local neighbor citizens with peer mediation-based ADR and MHL skills. In this multidisciplinary bottom-up approach, termed psychosocial peer mediation (PPM), participants learn to effectively manage and prevent conflicts in their own communities. Based on our field experience with implementing PPM in numerous refugee shelters across Germany between 2018 and 2021, we here provide relevant practical insights and discuss best practices, with a focus on addressing existing challenges and opportunities in the field.
Factors Regulating Retrotransposon Expression : Uncovering a Novel BRCA1 Related Mechanism in Ovarian Cancer
Creators: name: Alkailani, Maisa
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2021
Subjects: Retrotransposons
BRCA1
Ovarian
Cancer

description: Retrotransposons constitute about a third of our genome. It is challenging to identify the causes and consequences of retrotransposon expression in human disease due to hundreds of active genomic copies and poor conservation across species. We profiled genomic insertions of retrotransposons in ovarian cancer. RNAs exhibiting Bayesian correlation with retrotransposon RNA were analyzed to identify potential causes and consequences of retrotransposon expression in ovarian and breast cancers. This strategy found divergent inflammatory responses associated with retrotransposon expression in ovarian and breast cancer. It identified new factors inducing the expression of endogenous retrotransposons, including anti-viral responses and the tumor suppressor BRCA1. In cell lines, mouse ovarian epithelial cells and patient-derived tumor spheroids, BRCA1 promoted the accumulation of retrotransposon RNA and facilitated transcription of active families of retrotransposons and their insertion into the genome. Intriguingly, elevated retrotransposon expression predicted survival in ovarian cancer patients. Retrotransposons are part of a complex regulatory network in ovarian cancer, including BRCA1 contributing to patient survival. The above-described analysis strategy could also be used to identify the regulators and impacts of retrotransposons in various contexts of biology and disease in humans.
title: Ανίχνευση οργανοφφωσφορικών ενώσεων σε δείγματα ελαιολάδου με χρήση της τεχνικής SPME, GC-ECD
Creators: name: Παλαιογιάννη-Μπέλλου Άρτεμις
Publisher: name: Technical University of Crete
Year: 2008

description: Μη διαθέσιμο
title: Περιβαλλοντική & οικονομική αξιολόγηση ενεργειακής συμπεριφοράς κτιρίου τριτογενούς τομέα
Creators: name: Παυλίδου Αικατερίνη
Publisher: name: Technical University of Crete
Year: 2008

description: Μη διαθέσιμο
Multifrequency magnetic resonance elastography-based tomoelastography of the parotid glands–feasibility and reference values
Creators: name: Elsholtz, Fabian Henry Jürgen
name: Reiter, Rolf
name: Marticorena Garcia, Stephan Rodrigo
name: Braun, Jürgen
name: Sack, Ingolf
name: Hamm, Bernd
name: Schaafs, Lars-Arne
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Magnetic resonance elastography
subject: Tomoelastography
subject: Viscoelasticity
subject: Head and neck
subject: Parotid glands
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objectives: Accurate radiological differentiation of parotid tumors remains challenging despite recent technical advances in quantitative medical imaging. Multifrequency magnetic resonance elastography (MRE) could provide additional information on viscoelastic properties of normal and abnormal biological tissues. This study investigates the feasibility of MRE of the parotid glands in healthy participants and provides first reference values. Methods: 20 healthy participants underwent multifrequency MRE of both parotid glands at 3 Tesla. Shear waves at frequencies of 25, 30, 40, and 50 Hz were introduced into the participants' heads through the occiput using pressurized-air actuators. Shear wave speed (SWS) and loss angle of the shear modulus (φ) were reconstructed by tomoelastography post-processing as surrogate parameters for tissue stiffness and viscosity or fluidity. 10 participants underwent repeated MRE to determine test-retest reliability based on intraclass correlation coefficients. Results: All MRE datasets acquired could be included in the analysis. Mean SWS was 0.97 ± 0.13 m/s, and mean φ was 0.59 ± 0.05 rad, each for both sides combined and without notable lateral difference (p = 0.88/0.87). Test-retest reliability was good for SWS (ICC = 0.84 for both sides/ICC = 0.77 for the right side/ICC = 0.79 for the left side) and good to excellent for φ(ICC = 0.94/0.86/0.90). Conclusions: Multifrequency MRE of the parotid glands is feasible and reliable. This technique, therefore, is a promising method for investigating the viscoelastic properties of salivary gland tumors in future studies.
title: Συμβολή της τρισδιάστατης ηλεκτρικής τομογραφίας και της ανάλυσης των επιφανειακών κυμάτων στον σχεδιασμό λιμνοδεξαμενής στο οροπέδιο του Ομαλού Χανίων
Creators: name: Παγκράτης Παγκράτης
Publisher: name: Technical University of Crete
Year: 2012

description: Μη διαθέσιμο
Comparative analysis of phasic left atrial strain and left ventricular posterolateral strain pattern to discriminate Fabry cardiomyopathy from other forms of left ventricular hypertrophy
Creators: name: Frumkin, David
name: Mattig, Isabel
name: Laule, Nina
name: Al Daas, Maamoun
name: Canaan‐Kühl, Sima
name: Knebel, Fabian
name: Stangl, Karl
name: Brand, Anna
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: cardiomyopathy
subject: Fabry Disease
subject: left atrial deformation imaging
subject: left atrial strain
subject: left ventricular strain
subject: speckle tracking echocardiography
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: "Classical" echocardiographic signs of Fabry cardiomyopathy (FC), such as left ventricular hypertrophy (LVH), posterolateral strain impairment (PLSI), and papillary muscle hypertrophy may be of limited diagnostic accuracy in clinical practice. Our aim was to evaluate the diagnostic value of left atrial (LA) strain impairment compared to "classical" echocardiographic findings to discriminate FC. Methods: In standard echocardiographic assessments, we retrospectively analyzed the diagnostic value of the "classical" red flags of FC as well as LA strain in 20 FC patients and in 20 subjects with other causes of LVH. Receiver operating characteristic (ROC) curve analysis was performed to assess the respective diagnostic accuracy. Results: FC was confirmed in 20 patients by genetic testing. In the LVH group, 12 patients were classified by biopsy to have hypertrophic cardiomyopathy, two had hypertensive heart disease, and six LVH combined with borderline myocarditis. Global and regional left ventricular (LV) strain was not significantly different between groups while LA strain was significantly impaired in FC (Left atrial reservoir strain (LASr) 19.1%±8.4 in FC and 25.6%±8.9 in LVH, p = 0.009; left atrial conduction strain (LAScd) -8.4%±4.9 in FC and -15.9%±8.4 in LVH, p < 0.01). LAScd, with an area under the curve (AUC) of .81 (95% confidence interval [CI] .66-.96) showed the highest diagnostic accuracy to discriminate FC. The PLSI pattern showed an AUC of .49, quantification of papillary muscle hypertrophy an AUC of .47. Conclusion: Adding LA strain analysis to a comprehensive echocardiographic work-up of unclear LVH may be helpful to identify FC as a possible cause.
title: Γεωφυσική διασκόπηση στον αρχαιολογικό χώρο των αρχαίων Απτέρων του Ν. Χανίων
Creators: name: Ευθυμίου Μαρία
Publisher: name: Technical University of Crete
Year: 2012

description: Μη διαθέσιμο
Analyse der Eisoberflächenstruktur nach Bindung eines Antigefrierproteins und deren Zusammenhang mit der Gibbs-Thomson Gleichung
Creators: name: Gerhäuser, Julian
name: Gaukel, Volker
Publisher: name: Karlsruher Institut für Technologie (KIT)
Year: 2022
Subjects: AFP
Antigefrierprotein
Gibbs-Thomson
Oberfläche
Eis
Kristall
Krümmung
Radius

description: Antigefrieproteine (AFP) sind durch ihre Oberflächenbindung an Eiskristalle in der Lage, das Eiskristallwachstum und den Rekristallisationsprozess aufgrund des Gibbs-Thomson-Effekts zu beeinflussen. Die Bindung der AFP führt zur Bildung einer gekrümmten Eisoberfläche und es wird allgemein angenommen, dass es einen kritischen Eiskristallradius zwischen den Proteinen auf der Eisoberfläche gibt, der die maximale thermische Hysterese bestimmt. In dieser Arbeit wird mit Hilfe von Molekulardynamiksimulationen (MD) die resultierende dreidimensionale Oberflächenstruktur eines Eiskristalls unter Bindung eines AFP (spruce budworm AFP [1]) analysiert und die Lage des kritischen Radius ermittelt. Im Gegensatz zu früheren Erwartungen aus der Literatur konnten wir zeigen, dass sich der kritische Radius nicht direkt zwischen den adsorbierten Proteinen befindet. Darüber hinaus haben wir gezeigt, dass die minimale Temperatur, bei der das System nicht einfriert, sehr gut mit dem mit der Gibbs-Thomson-Gleichung berechneten Wert am kritischen Radius übereinstimmt, sofern dynamische Systembedingungen berücksichtigt werden. Dies beweist zum einen, dass der Gibbs-Thomson-Effekt die Grundlage der Eiskristallwachstumsbehinderung ist und dass MD-Simulationen für die Vorhersage der Schmelzpunktsenkung durch AFP geeignet sind [2]. Die gewonnenen Erkenntnisse sollen in zukünftigen Arbeiten auf andere Moleküle und Lösungen übertragen werden. [1] Graether SP, Kuiper MJ, Gagné SM, Walker VK, Jia Z, Sykes BD, Davies PL. Betahelix structure and ice-binding properties of a hyperactive antifreeze protein from an insect. Nature. 2000 Jul 20;406(6793):325-8. doi: 10.1038/35018610. PMID:10917537. [2] Gerhäuser J, Gaukel V. Detailed Analysis of the Ice Surface after Binding of an Insect Antifreeze Protein and Correlation with the Gibbs-Thomson Equation. Langmuir. 2021 Sep 29. doi: 10.1021/acs.langmuir.1c01620. Epub ahead of print. PMID:34585573.
Development of functional network architecture explains changes in children's altruistically motivated helping
Creators: name: Hoffmann, Ferdinand
name: Grosse Wiesmann, Charlotte
name: Singer, Tania
name: Steinbeis, Nikolaus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: altruistic motivation
subject: development
subject: empathy network
subject: helping
subject: middle childhood
subject: prosocial behaviour
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Childhood is marked by profound changes in prosocial behaviour. The underlying motivational mechanisms remain poorly understood. We investigated the development of altruistically motivated helping in middle childhood and the neurocognitive and -affective mechanisms driving this development. One-hundred and twenty seven 6-12 year-old children performed a novel gustatory costly helping task designed to measure altruistic motivations of helping behaviour. Neurocognitive and -affective mechanisms including emotion regulation, emotional clarity and attentional reorienting were assessed experimentally through an extensive task-battery while functional brain activity and connectivity were measured during an empathy for taste paradigm and during rest. Altruistically motivated helping increased with age. Out of all mechanisms probed for, only emotional clarity increased with age and accounted for altruistically motivated helping. This was associated with greater functional integration of the empathy-related network with fronto-parietal brain regions at rest. We isolate a highly specific neuroaffective mechanism as the crucial driver of altruistically motivated helping during child development.
Additional file 1: of Recurrent tumor-specific regulation of alternative polyadenylation of cancer-related genes
Creators: name: Xue, Zhuyi
name: Warren, René
name: Gibb, Ewan
name: MacMillan, Daniel
name: Wong, Johnathan
name: Chiu, Readman
name: Austin Hammond, S.
name: Yang, Chen
name: Nip, Ka
name: Ennis, Catherine
name: Hahn, Abigail
name: Reynolds, Sheila
name: Birol, Inanc
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary figures. It includes all supplementary figures except Figure S4. Figure S1. Benchmark of DaPars, KLEAT and ContextMap 2. Figure S2. Relevance of 114 select genes to cancer according to COSMIC. Figure S3. Detail of CS predictions. Figure S5. Distribution of 3’ UTR lengths of protein coding and NMD transcripts. (PDF 2210 kb)
title: Μελέτη διαστασιακών ιδιοτήτων των προϊόντων ημισυνεχούς λειοτρίβησης Σερπεντίνη και Χαλαζία
Creators: name: Εμμανουηλίδης Σταμάτης
Publisher: name: Technical University of Crete
Year: 2012

description: Μη διαθέσιμο
Vitamin D insufficiency is associated with metabolic syndrome independent of insulin resistance and obesity in young adults ‐ The Berlin Aging Study II
Creators: name: Buchmann, Nikolaus
name: Eckstein, Nils
name: Spira, Dominik
name: Demuth, Ilja
name: Steinhagen‐Thiessen, Elisabeth
name: Norman, Kristina
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: diabetes
subject: dietary vitamin D intake
subject: metabolic syndrome
subject: vitamin D
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Purpose: Age-related changes affect vitamin D absorption and metabolism. Low 25-hydroxyvitamin D concentrations have been reported as risk factor for the development of metabolic syndrome (MetS). However, recent evaluations suggest this association might be explained by obesity or insulin resistance (IR) in subjects with MetS. Our aim was to analyze associations between vitamin D insufficiency and MetS in a young cohort without diabetes and two senior cohorts with and without diabetes. Methods: Four hundred sixteen young and 1357 older BASE-II participants were analyzed. Type 2 diabetes (T2D) was defined according to European Society of Cardiology (ESC) guidelines, MetS as suggested by International Diabetes Federation/American Heart Association/National Heart, Lung and Blood Institute (IDF/AHA/NHLBI 2009). Vitamin D insufficiency was defined as 25-hydroxyvitamin D concentrations <50 nmol/L. Among other confounders, BMI and IR were taken into account. Results: MetS was prevalent in 7.7% of the young and in 35.6% of the older BASE-II participants and T2D occurred in 12.7% of the older participants. In young subjects without diabetes, vitamin D insufficiency was associated with an independent 3.2-fold increased odds of having MetS (OR: 3.2 CI: 1.0-8.7; p = 0.042). However, in the older participants, this association was lost once BMI was taken into account among those with diabetes, and once IR was taken into account among those without diabetes. Conclusion: Independent associations between vitamin D insufficiency and MetS were only found among young subjects without diabetes. In the older adults, BMI annihilated these associations among subjects without diabetes as did HOMA-IR among subjects with diabetes.
title: Έλεγχος συμβατότητας συνθετικών κονιαμάτων με τους δομικούς λίθους του ενετικού φρουρίου Κούλε
Creators: name: Γριζιώτη Αναστασία
Publisher: name: Technical University of Crete
Year: 2012

description: Μη διαθέσιμο
title: Έλεγχος δονήσεων ανατινάξεων διάνοιξης οδικής σήραγγας στα Τέμπη και διαχείριση κινδύνου επιπτώσεων σε αρχαιολογικής σημασίας Μνημείο
Creators: name: Μπαρμποπούλου Ευφημία
Publisher: name: Technical University of Crete
Year: 2012

description: Μη διαθέσιμο
title: Συγκριτική αξιολόγηση μεθόδων ελεγχόμενης ανατίναξης σε επιφανειακά και υπόγεια μέτωπα
Creators: name: Δασκαλάκη Κατερίνα
Publisher: name: Technical University of Crete
Year: 2012

description: Μη διαθέσιμο
title: Διερεύνηση της καταλληλότητας γεωυλικού από το μανδύα αποσάθρωσης φυλλιτών για την κατασκευή τάπητα σε Χ.Υ.Τ.Α.
Creators: name: Κόφφα Χρυσοστόμη
Publisher: name: Technical University of Crete
Year: 2012

description: Μη διαθέσιμο
title: Σχεδίαση και υλοποίηση ενός αυτόνομου πράκτορα για το παιχνίδι “League of Legends”
title: Design and implementation of an autonomous agent for the “League of Legends” game
Creators: name: Τριγκακης Δημητριος
Publisher: name: Technical University of Crete
Year: 2014

description: After the commercial success of the video game “Dota”, there has been increasing attention given to the Multiplayer online battle arena (MOBA) subgenre of Real Time Strategy (RTS) games. The creation of agents able to play autonomously within such games is sometimes limited by the absence of a public application programming interface (API). This applies to the popular game “League of Legends”, which was greatly inspired by Dota. The few computer-assisted players provided by the designers of this game range from beginner to intermediate, but have direct access to the private API inside the game. This thesis introduces a novel way to handle autonomous agent creation in such games, where access to the game state is limited to the information displayed on the user’s screen. The proposed methods come close to what a human player does, since there is a perception phase, which relies mainly on visual analysis, and a decision phase, whose outcome affects the game through emulation of the keyboard and mouse input devices. To achieve this we use screen capture on the game’s interface and computer vision algorithms to detect important information. Then, we use artificial intelligence algorithms to encode behaviors for the game character we control. Realizing this perception-decision-action cycle is very demanding in terms of computational resources, however our optimized implementation manages to meet the real-time requirements of the game. Our autonomous agent for the “League of Legends” game is able to achieve intermediate level of play and is quite competent against the designer-provided agents and also against beginner human players.
Real‐world evidence on clinical outcomes of people with type 1 diabetes using open‐source and commercial automated insulin dosing systems: A systematic review
Creators: name: Knoll, Christine
name: Peacock, Sofia
name: Wäldchen, Mandy
name: Cooper, Drew
name: Aulakh, Simran Kaur
name: Raile, Klemens
name: Hussain, Sufyan
name: Braune, Katarina
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: automated insulin delivery
subject: automated insulin dosing
subject: diabetes mellitus
subject: diabetes technology
subject: open-source
subject: real-world evidence
subject: type 1 diabetes
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Aims: Several commercial and open-source automated insulin dosing (AID) systems have recently been developed and are now used by an increasing number of people with diabetes (PwD). This systematic review explored the current status of real-world evidence on the latest available AID systems in helping to understand their safety and effectiveness. Methods: A systematic review of real-world studies on the effect of commercial and open-source AID system use on clinical outcomes was conducted employing a devised protocol (PROSPERO ID 257354). Results: Of 441 initially identified studies, 21 published 2018-2021 were included: 12 for Medtronic 670G; one for Tandem Control-IQ; one for Diabeloop DBLG1; two for AndroidAPS; one for OpenAPS; one for Loop; three comparing various types of AID systems. These studies found that several types of AID systems improve Time-in-Range and haemoglobin A1c (HbA1c ) with minimal concerns around severe hypoglycaemia. These improvements were observed in open-source and commercially developed AID systems alike. Conclusions: Commercially developed and open-source AID systems represent effective and safe treatment options for PwD of several age groups and genders. Alongside evidence from randomized clinical trials, real-world studies on AID systems and their effects on glycaemic outcomes are a helpful method for evaluating their safety and effectiveness.
El costo de realizar investigación local: implicaciones para las trayectorias científicas y la producción de conocimiento
Creators: name: Di Césare, Victoria
name: Robinson-García, Nicolás
Publisher: name: Zenodo
Year: 2023
Subjects: Investigación local
Trayectorias científicas
Producción de conocimiento científico
Cienciometría

description: Este proyecto doctoral apunta a comprender los efectos que tienen las nociones de excelencia científica, generalmente sesgadas contra la heterogeneidad cognitiva, geográfica y social, sobre las trayectorias de los científicos que llevan a cabo investigación local. Considerando la dicotomía Norte Global/Sur Global como marco interpretativo, la premisa de partida es que los investigadores del Sur Global abocados a temas más localizados ven sus trayectorias científicas más negativamente afectadas en comparación con sus pares del Sur que trabajan tópicos menos localizados e, incluso, con los investigadores del Norte enfocados en agendas más o menos locales. Tal daño toma la forma de menos citas, recursos, reconocimiento y oportunidades, y va en detrimento tanto de sus carreras, como de la producción de conocimiento de los países menos desarrollados. El objetivo principal es caracterizar dichas trayectorias en relación con la investigación local y el conocimiento situado. Para ello, se definirá teórica y operacionalmente la investigación local; se describirá a los investigadores abocados a la investigación local de acuerdo con su contexto social, su labor profesional y su perfil científico; y se estudiarán los efectos que los incentivos y la movilidad tienen sobre la producción de conocimiento local. Esta propuesta combina enfoques cualitativos y cuantitativos propios de los Estudios Sociales de la Ciencia y de la Bibliometría respectivamente. Cada objetivo específico será abordado con un diseño metodológico particular que incluirá, entre otros, análisis documental, análisis causal, encuesta, estadística descriptiva, cruzamiento de variables y simulación. La relevancia radica en el aún irresuelto conflicto entre la necesidad de los países del Sur Global de llevar a cabo investigación local para atender problemáticas específicas, y la obligación tácita de desempeñarse al nivel de los estándares internacionales de excelencia para obtener financiamiento y reconocimiento.
description: Victoria Di Césare cuenta con el apoyo de un contrato FPI del Ministerio de Ciencia e Innovación de España (PRE2021-097022).