cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Rhamnus cathartica Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rhamnaceae
Rhamnus
Rhamnus cathartica

description: Rhamnus cathartica Linnaeus, Species Plantarum 1: 193. 1753.
"Habitat in Europae australioris sepibus." RCN: 1549.
Lectotype (Schirarend in Jarvis & al., Regnum Veg. 127: 81. 1993): Herb. Linn. No. 262.1 (LINN).
Generitype of Rhamnus Linnaeus (vide Hitchcock, Prop. Brit. Bot.: 133. 1929).
Current name: Rhamnus cathartica L. (Rhamnaceae).
Note: Specific epithet spelled “catharticus” in the protologue.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 791, DOI: 10.5281/zenodo.291971
Additional file 5 of The association between RGS4 and choline in cardiac fibrosis
Creators: name: Guo, Jing
name: Hang, Pengzhou
name: Yu, Jie
name: Li, Wen
name: Zhao, Xiuye
name: Sun, Yue
name: Fan, Ziyi
name: Du, Zhimin
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 4. Full protein bands.
Reminiscences of Margaret S. Mahler 1974
Publisher: name: Columbia University
Year: 2019
Subjects: Psychoanalysts
Psychiatrists
Psychoanalysis
Child analysis

description: Youth, education in Hungary and Germany; work with von Pirquet and Moll Clinics, Vienna; undergoing analysis; association with second generation psychoanalysts; acceptance in Vienna Psychoanalytic Institute, 1933; Rorschach studies; establishemnt of first psychoanalytic child guidance clinic, 1933; Nazi oppression, escape to New York City; work with New York Psychiatric Institute; child development, analysis and psychosis studies.
On the use of nonlinear regularization in inverse method for the tachocline profile determination
Creators: name: Corbard, T.
name: Berthomieu, G.
name: Provost, J.
name: Blanc-Féraud, L.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Inversions of rotational splittings have shown that the surface layers and the so-called solar tachocline at the base of the convection zone are regions in which high radial gradients of the rotation rate occur. The usual regularization methods tend to smooth out every high gradients in the solution and may not be appropriate for the study of a zone like the tachocline. In this paper we use nonlinear regularization methods that are developed for edge-preserving regularization in computed imaging (e.g. Blanc-Féraud et al. 1995) and we apply them in the helioseismic context of rotational inversions.
description: 6 pages, 5 figures, postscript available at http://www.obs-nice.fr/corbard/corbard_prp.html
M1-GRE
Creators: name: DOAN Mai Linh
Publisher: name: Sismer
Year: 2012

description: Au sein de l'UFR PHysique, Ingénierie, Terre, Environnement, Mécanique (PHITEM) de l'Université Grenoble-Alpes, le master Sciences de la Terre et des Planètes, Environnement (STPE) a pour objectif de former des étudiants aux outils modernes de la physique, de la chimie et de la géologie permettant d'aborder de façon quantitative les sciences de la Planète. L'atelier de « Géophysique Marine » est un enseignement obligatoire pour les étudiants de trois parcours : «Earth System Sciences», «Géoressources» et «Geophysics and Earth Imaging». Il se déroule durant le second trimestre de la 1ère année du master. Les élèves maîtrisent alors les outils théoriques de base (propagation des ondes, bases de sédimentologie) acquis au cours du premier trimestre et vont pouvoir appliquer leur connaissance lors d'un stage pratique permettant de mettre en oeuvre l'ensemble de la démarche, de l'acquisition à l'interprétation des profils sismiques. Il compte pour 3 ECTS.
Rhamnus saxatilis subsp. infectoria P. Fourn.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rhamnaceae
Rhamnus
Rhamnus saxatilis
Rhamnus saxatilis jacq. subsp. infectoria (l.) p. fourn.

description: Rhamnus infectoria Linnaeus, Systema Naturae, ed. 12, 2: 178; Mantissa Plantarum: 49. 1767.
"Habitat in Hispania, Gallia, Italia." RCN: 1550.
Type not designated.
Original material: Scopoli 45, Herb. Linn. No. 262.2? (LINN); Herb. Burser XXV: 9 (UPS); [icon] in Clusius, Rar. Pl. Hist. 1: 111. 1601; [icon] in Bauhin & Cherler, Hist. Pl. Univ. 1(2): 58. 1650.
Current name: Rhamnus saxatilis Jacq. subsp. infectoria (L.) P. Fourn. (Rhamnaceae).
Note: Specific epithet spelled “infectorius” in the protologue.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 791, DOI: 10.5281/zenodo.291971
Hierarchical One Permutation Hashing: Efficient Multimedia Near Duplicate Detection
Creators: name: Zhang, Chengyuan
name: Lin, Yunwu
name: Zhu, Lei
name: Yuan, XinPan
name: Long, Jun
name: Huang, Fang
Publisher: name: arXiv
Year: 2018
Subjects: subject: Multimedia (cs.MM)
subject: Databases (cs.DB)
subject: FOS: Computer and information sciences

description: With advances in multimedia technologies and the proliferation of smart phone, digital cameras, storage devices, there are a rapidly growing massive amount of multimedia data collected in many applications such as multimedia retrieval and management system, in which the data element is composed of text, image, video and audio. Consequently, the study of multimedia near duplicate detection has attracted significant concern from research organizations and commercial communities. Traditional solution minwish hashing (\minwise) faces two challenges: expensive preprocessing time and lower comparison speed. Thus, this work first introduce a hashing method called one permutation hashing (\oph) to shun the costly preprocessing time. Based on \oph, a more efficient strategy group based one permutation hashing (\goph) is developed to deal with the high comparison time. Based on the fact that the similarity of most multimedia data is not very high, this work design an new hashing method namely hierarchical one permutation hashing (\hoph) to further improve the performance. Comprehensive experiments on real multimedia datasets clearly show that with similar accuracy \hoph is five to seven times faster than
description: Accepted to appear at Multimedia Tools and Applications
Gene expression patterns in oculocutaneous albinism type 2 (OCA2) patients of African descent with and without ephelides
Creators: name: Thandiswa Ngcungcu
name: Vlasova, Anna
name: Guigo, Roderic
name: Ramsay, Michele
Publisher: name: Gates Open Research
Year: 2019

description: Oculocutaneous albinism type 2 (OCA2) is the most common autosomal recessive disorder in Southern Africa. OCA2 is caused by recessive mutations in the OCA2 gene with the most common mutation being a 2.7kb deletion. Interestingly, 61% sub-Saharan African OCA2 patients develop dark patches known as ephelides in sun exposed skin, suggesting that these ephelides develop in response to UV exposure and appear to be inherited and protective against UV radiation damage.

It is unclear how these ephelides arise or which genetic mechanisms lead to their development in some patients but not in all. The aim of this study was to determine the gene expression patterns in OCA2 patients with and without ephelides by using whole transcriptome analysis using RNA-seq. Single 4 mm skin punch biopsies were taken from individuals with (n=4) and without (n=6) ephelides. Two samples were collected from each patient, one from the upper arm close to the armpit (non-sun exposed: NSE) and a sample from the forearm (sun exposed: SE). In individuals with ephelides, the biopsy was taken from the ephelide site too.

Paired-end RNAseq libraries were sequenced using the HiSeq platform. Reads were mapped using STARR to the human genome v.38 and gencode annotation v.26. Differential expression analysis was done using EdgeR.

There are 10 differentially expressed genes when SE skin is compared with ephelide skin in individuals with ephelides with the SPRR2A gene showing the most differential expression. SPRRA2 has been shown to have higher expression in hyperpigmented lesions of Korean women with melasma. These findings warrant validation of these expression patterns and further exploration of the SPRRA2 geneial expression.
Development of an ex-vivo transmission blocking assay for Plasmodium field-isolated gametocytes
Creators: name: Dinkorma Ouologuem
name: Dembele, Laurent
name: Dara, Antoine
name: Nouhoum Diallo
name: Fatoumata I. Ballo
name: Sekou Koumare
name: Cheick P. O. Sangare
name: Aboubecrin S. Haidara
name: Yacouba N. Barre
name: Francois  Dao
name: Diagassan Doumbia
name: Amadou Daou
name: Fatoumata Cisse
name: Ousmaila Diakite
name: Fanta  Sogore
name: Daman Sylla
name: Sacko, Adama
name: Coulibaly, Mamadou
name: Abdoulaye Djimde
Publisher: name: Gates Open Research
Year: 2019

description: For the successful control of malaria, there is an urgent need to identify safe transmission-blocking therapies and tools that reliably measure the blocking properties of these therapies.
The current tools for the assessment of transmission-blocking drug activity are technically challenging, challenging to implement in the LMIC laboratories. Besides, the existing tools often rely on conventional laboratory strains which may not be reflective of the plasmodial population circulating in malaria-endemic regions. The development of robust assay using Plasmodium isolates and implementable in most LMIC laboratories are crucial for drug discovery.
Our project aims to develop an assay to measure the transmission-blocking activity drugs by exploiting parasite isolated from malaria infected-volunteers. Parasites will be exposed to selected drugs, and the transmission-blocking capability will be evaluated using the gold standard mosquito feeding assay.
This innovative work is anticipated to be a useful addition to the current tools for drug discovery and to support the malaria eradication agenda.
DYSACOTE
Creators: name: BELLENEY Déborah
Publisher: name: Sismer
Year: 2020

description: La vulnérabilité des côtes d'accumulation et d'ablation aux phénomènes d'érosion côtière est une problématique et un enjeu sociétal auxquels les gestionnaires du littoral s'attachent aujourd'hui à répondre objectivement. Les connaissances actuelles montrent que le recul du trait de côte est en parti dû à la hausse du niveau marin, à la récurrence des tempêtes et à la disponibilité en matériel sédimentaire au sein de la cellule littorale. Il s'avère, par ailleurs, que le fonctionnement et l'évolution de ces accumulations littorales sont fortement dépendantes des transferts sédimentaires long-shore et cross-shore qui opèrent dans l'espace d'avant-côte, entre la plage et la plate-forme continentale interne. C'est, en effet, dans ce compartiment compris entre le jet de rive (déferlement des vagues) et la profondeur de fermeture (profondeur limite de remaniement du sédiment) que sont observées les plus importantes remobilisations de matériel. La connaissance de ces transferts sédimentaires est donc une clé de compréhension du fonctionnement et des évolutions des accumulations littorales. Les études actuelles se concentrent essentiellement sur la connaissance de la partie intertidale et dunaire, alors que les transferts entre la partie intertidale et subtidale sont encore peu étudiés. Il apparait donc une lacune dans l'observation, la qualification et la quantification de ces transports sédimentaires subtidaux, dont la caractérisation contribuerait pourtant à améliorer les stratégies de gestion des littoraux afin de réduire les risques de submersion marine. Pour répondre à ce manque de données, la mission DySACote avait pour objectif d'identifier les évolutions morphodynamiques de ces accumulations littorales et d'en cartographier les épaisseurs sédimentaires. Ces travaux ont été menés sur des systèmes hydro-sédimentaires fermés et aux limites caractérisées en Bretagne Occidentale, dans le sud de la baie de Bénodet/Loctudy et dans l'anse de Dinan à l'ouest de la Presqu'ile de Crozon, à travers l'acquisition et l'analyse de profils bathymétriques et sismiques. L'interprétation des données géophysiques et morphologiques des structures sédimentaires couplée à l'analyse lithologique par prélèvements sédimentaires est en cours. L'interprétation des acquisitions est en cours. Elle est associée aux résultats des acquisitions équivalentes réalisées sur la côte nord et la côte occidentale du Finistère. L'ensemble de ces données et leur interprétation a pour objectif à terme, de définir un schéma de fonctionnement du système côtier en matière de transferts sédimentaires et de mieux préciser la profondeur de fermeture.
Scale Invariance of Rich Cluster Abundance: A Possible Test for Models of Structure Formation
Creators: name: Xu, Wen
name: Fang, Li-Zhi
name: Wu, Xiang-Ping
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We investigate the dependence of cluster abundance $n(>M,r_{cl})$, i.e., the number density of clusters with mass larger than $M$ within radius $r_{cl}$, on scale parameter $r_{cl}$. Using numerical simulations of clusters in the CDM cosmogonic theories, we notice that the abundance of rich clusters shows a simple scale invariance such that $n[>(r_{cl}/r_0)^αM, r_{cl}]= n(>M,r_0)$, in which the scaling index $α$ remains constant in a scale range where halo clustering is fully developed. The abundances of scale $r_{cl}$ clusters identified from IRAS are found basically to follow this scaling, and yield $α\sim 0.5$ in the range $1.5 < r_{cl} < 4 h^{-1}$Mpc. The scaling gains further supports from independent measurements of the index $α$ using samples of X-ray and gravitational lensing mass estimates. We find that all the results agree within error limit as: $α\sim 0.5 - 0.7$ in the range of $1.5 < r_{cl} < 4 h^{-1}$Mpc. These numbers are in good consistency with the predictions of OCDM ($Ω_M=0.3$) and LCDM ($Ω_M+Ω_Λ =1$), while the standard CDM model has different behavior. The current result seems to favor models with a low mass density.
description: 20 pages, 7 figures, accepted for publication in ApJ
Using satellite-based data to support agricultural decision-making in Rwanda
Creators: name: Beach, Robert
name: Lapidus, Daniel
name: Hegarty-Craver, Meghan
name: Polly, Jason
name: O'Neil, Margaret
name: Rineer, James
name: Temple, Dorota
Publisher: name: Gates Open Research
Year: 2019

description: Addressing the grand challenge of achieving global food security for a growing population within land and other resource constraints requires significant advances in production efficiency and sustainability. Systems relying on satellite-based data have the near-term potential to provide stakeholders with information on crop production, status, and predicted yield that is timely, covers large areas, captures spatial and temporal detail, and can be obtained at low cost, potentially contributing to better decisions. We develop methods and tools to acquire and process geospatial information from multiple data streams and apply to analyses of Rwandan agriculture. We combine satellite imagery with images collected using unmanned aerial vehicles and field survey data and apply machine learning techniques to provide rapid, consistent image processing and analysis. These data are used to estimate area cultivated, identify major crops, and assess crop growth over time during the growing season.
PERLE
Creators: name: CONAN Pascal
Publisher: name: Sismer
Year: 2019

description: PERLE - Formation, dispersion et rôle écologique des Eaux Intermédiaires en MéditerranéeLes 3 campagnes PERLE ("Pelagic Ecosystem Response in the Levant Experiment") s'inscrivent dans le cadre du projet MERMEX (MISTRALS) et visent à comprendre la formation et la dispersion des eaux intermédiaires (LIW et CIW) en Méditerranée orientale, et leur impact écosystémique. PERLE constitue une action hauturière majeure du projet MERMEX, en faisant suite à l'opération DEWEX (2013-2014) en méditerranée nord occidentale. En combinant observations hauturières, plateformes autonomes et modélisation, PERLE cherche à évaluer l'évolution des propriétés de cette masse d'eau clé pour la circulation, les flux de nutriments et la structuration des écosystèmes planctoniques. Malgré des contraintes géopolitiques et sanitaires, les campagnes PERLE2, PERLE3 et PERLE4 ont permis de documenter les caractéristiques physiques et biogéochimiques des masses d'eau intermédiaires. Les objectifs de la série PERLE sont de : caractériser les régions de formation de la LIW et décrire les différentes phases de formation, décrire l'effet des structures tourbillonnaires à mésoéchelle, comprendre l'évolution des cycles biogéochimiques au sein de la veine d'eau intermédiaire au cours de son transit, améliorer les performances des modèles numériques 'physique-biogéochimie' grâce aux données collectées.
Heavy sterile neutrinos in stellar core-collapse
Creators: name: Rembiasz, Tomasz
name: Obergaulinger, Martin
name: Masip, Manuel
name: Pérez-García, M. Ángeles
name: Aloy, Miguel-Ángel
name: Albertus, Conrado
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We perform spherically symmetric simulations of the core collapse of a single progenitor star of zero age main sequence mass $M_{\rm ZAMS} = 15 \, M_{\odot}$ with two models of heavy sterile neutrinos in the mass range of hundred MeV$/c^2$. According to both models, these hypothetical particles are copiously produced in the center, stream outwards a subsequently decay releasing energy into final states (including neutrinos) of the Standard Model. We find that they can lead to a successful explosion in otherwise non-exploding progenitors. Depending on their unknown parameters (e.g., mass and coupling constants with matter), we obtain either no explosion or an explosion of one of two types, i.e., through heating of gas downstream of the stalled shock wave, similarly to the standard scenario for supernova explosions or through heating of gas at higher radii that ejects matter from the outer core or the envelope while the center continues to accrete matter. In both cases, the explosion energies can be very high. We presume that this new type of explosion would produce an electromagnetic signal that significantly differs from common events because of the relative absence of heavy elements in the ejecta. The combination of core-collapse simulations and astrophysical observations may further constrain the parameters of the sterile neutrinos.
description: 16 pages, 7 figures, accepted for publication in PRD
Metagenomic sequencing of clinical human samples for zoonotic viral etiology in Madagascar
Creators: name: Brook, Cara
name: Hafaliana Christian Ranaivoson
name: Tsiry Hasina Randriambolamanantsoa
name: Guth, Sarah
name: Jean-Michel Héraud
name: Ahyong, Vida
name: Kistler, Amy
name: Kalantar, Katrina
name: Tato, Cristina
name: Quake, Steve
name: DeRisi, Joe
Publisher: name: Gates Open Research
Year: 2019

description: Institut Pasteur of Madagascar is the national reference laboratory for influenza, measles, rubella, polioviruses, rabies, arboviruses, mycobacteria, and plague, receiving clinical specimens from public hospitals across 114 districts. We present results from an initial screening using metagenomic Next Generation Sequencing (mNGS) techniques of for 323 samples (104 nasopharyngeal swabs, 86 serum samples, and 95 whole blood samples) collected in part with routine surveillance in Madagascar. The bulk of these samples (>90%) represent undiagnosed fevers, which [reviousy assayed negative using standard clinical PCR- and ELISA-based screening techniques. We assayed this subset of samples as part of our training as recent recipients of the Nill & Melinda Gates Foundation Grand Challenges Explorations award “Applications of Next Generation Sequencing for Pathogen Detection.” Nasopharyngeal (NP) swabs returned the highest quality results in our dataset, yielding high quality viral hits (including several complete genomes) for common human respiratory fevers, including rhinoviruses, respiratory syncytial viruses (RSV), and betacoronaviruses. Ten of eleven positive control samples were accurately identified from the NP swabs. Serum and whole blood samples were severely degraded as a result of poor sample storage procedures and multiple thaw-refreeze cycles upstream of acquisition of the samples. As a result, no RNA-virus positive controls were accurately identified from these samples, but DNA pathogens, including multiple Plasmodium spp. infections were reliably sequenced. Additionally, previously unrecognized pegiviruses were identified in these samples. In part with this Gates Grand Challenges award, we are also simultaneously sequencing blood, urine, and fecal samples derived from known bat reservoirs of circulating henipaviruses and filoviruses in Madagascar. Though no zoonotic agents have yet been identified in human or bat samples, betacoronavirus sequences from both taxa cluster together in phylogenetic analysis. Metagenomic Next Generation Sequencing offers a promising platform for unbiased assay and identification of the etiology of disease in undiagnosed clinical cases.
Observationally Determining the Properties of Dark Matter
Creators: name: Hu, Wayne
name: Eisenstein, Daniel J.
name: Tegmark, Max
name: White, Martin
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Determining the properties of the dark components of the universe remains one of the outstanding challenges in cosmology. We explore how upcoming CMB anisotropy measurements, galaxy power spectrum data, and supernova (SN) distance measurements can observationally constrain their gravitational properties with minimal assumptions on the theoretical side. SN observations currently suggest the existence of dark matter with an exotic equation of state p/rho < -1/3 that accelerates the expansion of the universe. When combined with CMB anisotropy measurements, SN or galaxy survey data can in principle determine the equation of state and density of this component separately, regardless of their value, as long as the universe is spatially flat. Combining these pairs creates a sharp consistency check. If p/rho > -1/2, then the clustering behavior (sound speed) of the dark component can be determined so as to test the scalar-field ``quintessence'' hypothesis. If the exotic matter turns out instead to be simply a cosmological constant (p/rho = -1), the combination of CMB and galaxy survey data should provide a significant detection of the remaining dark matter, the neutrino background radiation (NBR). The gross effect of its density or temperature on the expansion rate is ill-constrained as it is can be mimicked by a change in the matter density. However, anisotropies of the NBR break this degeneracy and should be detectable by upcoming experiments.
description: 16 pages, 10 figures, RevTeX, submitted to PRD
Inhibition of O-acetylserine sulfhydrylase by fluoroalanine derivatives
Creators: name: Franko, Nina
name: Grammatoglou, Konstantinos
name: Campanini, Barbara
name: Costantino, Gabriele
name: Jirgensons, Aigars
name: Mozzarelli, Andrea
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: O-acetylserine sulfhydrylase (OASS) is the pyridoxal 5′-phosphate dependent enzyme that catalyses the formation of L-cysteine in bacteria and plants. Its inactivation is pursued as a strategy for the identification of novel antibiotics that, targeting dispensable proteins, holds a great promise for circumventing resistance development. In the present study, we have investigated the reactivity of Salmonella enterica serovar Typhimurium OASS-A and OASS-B isozymes with fluoroalanine derivatives. Monofluoroalanine reacts with OASS-A and OASS-B forming either a stable or a metastable α-aminoacrylate Schiff’s base, respectively, as proved by spectral changes. This finding indicates that monofluoroalanine is a substrate analogue, as previously found for other beta-halogenalanine derivatives. Trifluoroalanine caused different and time-dependent absorbance and fluorescence spectral changes for the two isozymes and is associated with irreversible inhibition. The time course of enzyme inactivation was found to be characterised by a biphasic behaviour. Partially distinct inactivation mechanisms for OASS-A and OASS-B are proposed.
The Atomic and Electronic Structure of Liquid N- Methylformamide as Determined from Diffraction Experiments
Creators: name: Neuefeind, J.
name: Zeidler, M. D.
name: Poulsen, H. F.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: The structure of liquid N-methylformamide (NMF) has been investigated using synchrotron radiation at 77 and 95 keV. The use of high energy photons has several advantages, in this case especially the large accessible momentum transfer range, the low absorption and the direct comparability with neutron diffraction. The range of momentum transfer covered is 0.6 Å$^{-1}
description: Accepted for publication in Molecular Physics, LaTex file, 12 pages, figures not included
Rhamnus frangula Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rhamnaceae
Rhamnus
Rhamnus frangula

description: Rhamnus frangula, spec. nov.
 3. Rhamnus inermis, floribus monogynis hermaphroditis, foliis integerrimis. Hort. cliff. 70. Fl. suec. 224. Mat. med. 73. Roy. lugdb. 224.
 Rhamnus inermis, foliis annuis. Fl. lapp.60.
 Alnus nigra baccifera. Bauh. pin. 428.
 Frangula. Dod. pempt. 784.
 Habitat in Europae borealis nemorosis humidiusculis. ♄
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 193, DOI: 10.5281/zenodo.3931989
Reminiscences of Margret Craver 1987
Publisher: name: Columbia University
Year: 2019
Subjects: Educators
Jewelers
Jewelry making
Art--Study and teaching
Occupational therapy

description: Childhood and early education in Kansas; University of Kansas, 1925-29; development as an artist; Greenwich house, New York City, 1929; elementary school teacher in Kansas, 1930-32; Art professor, School of the Museum Art Association, 1932; studies in Stockholm, 1935; pilot shop work with occupational therapists, 1944; teacher at Handy and Harman, 1947-50; return to commission work in Massachusetts, 1950; techniques of jewelry design, metal smithing, enameling; impressions of Baron Eric Fleming.
Additional file of The association between RGS4 and choline in cardiac fibrosis
Creators: name: Guo, Jing
name: Hang, Pengzhou
name: Yu, Jie
name: Li, Wen
name: Zhao, Xiuye
name: Sun, Yue
name: Fan, Ziyi
name: Du, Zhimin
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file of The association between RGS4 and choline in cardiac fibrosis
On the Nature of Pulsar Radio Emission
Creators: name: Lyutikov, Maxim
name: Blandford, Roger D.
name: Machabeli, George
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A theory of pulsar radio emission generation, in which the observed waves are produced directly by maser-type plasma instabilities operating at the anomalous cyclotron-Cherenkov resonance $ω- k_{\parallel} v_{\parallel} + ω_B/ γ_{res}=0$ and the Cherenkov-drift resonance $ω- k_{\parallel} v_{\parallel} - k_{\perp} u_d =0$, is capable of explaining the main observational characteristics of pulsar radio emission. The instabilities are due to the interaction of the fast particles from the primary beam and the tail of the distribution with the normal modes of a strongly magnetized one-dimensional electron-positron plasma. The waves emitted at these resonances are vacuum-like, electromagnetic waves that may leave the magnetosphere directly. In this model, the cyclotron-Cherenkov instability is responsible for core emission pattern and the Cherenkov-drift instability produces conal emission. The conditions for the development of the cyclotron-Cherenkov instability are satisfied for both typical and millisecond pulsars provided that the streaming energy of the bulk plasma is not very high $γ_p \approx 10$. In a typical pulsar the cyclotron-Cherenkov and Cherenkov-drift resonances occur in the outer parts of magnetosphere at $r_{res} \approx 10^9 cm$. This theory can account for various aspects of pulsar phenomenology including the morphology of the pulses, their polarization properties and their spectral behavior. We propose several observational tests for the theory. The most prominent prediction are the high altitudes of the emission region and the linear polarization of conal emission in the plane orthogonal to the local osculating plane of the magnetic field.
description: 39 pages, 10 figures
Reminiscences of Marian Van Tuyl Campbell 1979
Publisher: name: Columbia University
Year: 2019
Subjects: Dancers
Modern dance
Choreography
Dance teachers

description: Early experiences in dance; career as teacher at University of Michigan and University of Chicago; early training in New York with Martha Hill and Louis Horst; study in Graham, Holm, and Humphrey/Weidman studios; impact of Bennington Summer School; rehearsals for PANORAMA; impressions of choreography presented at school; physical education teachers at Bennington; Ballet Caravan performances; social life at the summer school; impressions of Martha Graham, Louis Horst, Mary Jo Shelly; work as a fellow of the school, 1938; John Martin and the class in dance criticism; Mills College idea; subsequent dance experiences.
Frangula alnus Mill.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rhamnaceae
Frangula
Frangula alnus

description: Rhamnus frangula Linnaeus, Species Plantarum 1: 193. 1753.
"Habitat in Europae borealis nemorosis humidiusculis." RCN: 1563.
Lectotype (Jonsell & Jarvis in Nordic J. Bot. 22: 80. 2002): Herb. Clifford: 70, Rhamnus 5 (BM-000558106).
Current name: Frangula alnus Mill. (Rhamnaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 791, DOI: 10.5281/zenodo.291971
Pharmacological Effect of Histone Deacetylase Inhibitors on Pulmonary Arterial Hypertension
Creators: name: Chen, Chien-Nien
Publisher: name: Imperial College London
Year: 2012

description: Pulmonary hypertension (PH) is characterized by structural remodelling of pulmonary arteries and arterioles, the result, at least in part, of excessive cell proliferation, resistance to cell death and hyperactive inflammatory reactions. Currently available treatments targeting the hyper-proliferative and pro-inflammatory pathology are limited. Epigenetic programming, dynamically regulated by histone acetylation, is an important mechanism for cell proliferation and survival. Aberrant changes of histone acetylation, modulated by histone deacetylase (HDAC), are shown in many proliferative and inflammatory disorders, especially cancer, and may contribute to the phenotypical changes in remodelling and overall to the development of PH. Hypothetically, HDAC inhibitors have therapeutic potential by reversing the imbalance of acetylation. I examined the correlations between HDAC expression and PH development, followed by evaluation of the pharmacological effects and possible mechanisms of two HDAC inhibitors, class I inhibitor valproic acid (VPA) and pan-HDAC inhibitor suberoylanilide hydroxamic acid (SAHA), on animal models and cellular systems. Altered HDAC expression, specifically increased HDAC1 and HDAC5 along with elevation of anti-apoptotic marker Bcl-2, were found in lungs from patients with idiopathic pulmonary arterial hypertension and chronically hypoxic rats. In in vivo studies, VPA and SAHA ameliorated the established PH in both hypoxia- and monocrotalineinduced PH rat models, by reducing pulmonary arterial pressure, right ventricular hypertrophy and pulmonary vascular muscularization, in parallel with increasing histone acetylation. In in vitro studies, VPA and SAHA inhibited stimulated cell growth of pulmonary artery smooth muscle cells and cytokine release from endothelial cells. Biochemical analysis indicated these two inhibitors exert anti-proliferative effects comprising cell cycle arrest by upregulation of p21 and apoptotic induction by downregulation of Bcl-2. Collectively, this study shows the contribution of abnormal HDAC activity to vascular pathology of PH and provides a preclinical basis to further explore the therapeutic potential of HDAC inhibitors in human PH.
Metformin and its sulphonamide derivative simultaneously potentiateanti-cholinesterase activity of donepezil and inhibit beta-amyloid aggregation
Creators: name: Markowicz-Piasecka, Magdalena
name: Huttunen, Kristiina M.
name: Sikora, Joanna
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The aim of this study was to assess in vitro the effects of sulphenamide and sulphonamide derivatives of metformin on the activity of human acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), establish the type of inhibition, and assess the potential synergism between biguanides and donepezil towards both cholinesterases (ChEs) and the effects on the β-amyloid aggregation. Sulphonamide 5 with para-trifluoromethyl- and ortho-nitro substituents in aromatic ring inhibited AChE in a mixed-type manner at micromolar concentrations (IC50 = 212.5 ± 48.3 µmol/L). The binary mixtures of donepezil and biguanides produce an anti-AChE effect, which was greater than either compound had alone. A combination of donepezil and sulphonamide 5 improved the IC50 value by 170 times. Compound 5 at 200 µmol/L inhibited Aβ aggregation by ∼20%. In conclusion, para-trifluoromethyl-ortho-nitro-benzenesulphonamide presents highly beneficial anti-AChE and anti-Aβ aggregation properties which could serve as a promising starting point for the design and development of novel biguanide-based candidates for AD treatment.
Additional file 2 of The association between RGS4 and choline in cardiac fibrosis
Creators: name: Guo, Jing
name: Hang, Pengzhou
name: Yu, Jie
name: Li, Wen
name: Zhao, Xiuye
name: Sun, Yue
name: Fan, Ziyi
name: Du, Zhimin
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. The RGS4 protein level after knocking down and overexpression.
On the Association of Gamma-Ray Bursts with Supernovae
Creators: name: Kippen, R. M.
name: Briggs, M. S.
name: Kommers, J. M.
name: Kouveliotou, C.
name: Hurley, K.
name: Robinson, C. R.
name: van Paradijs, J.
name: Hartmann, D. H.
name: Galama, T. J.
name: Vreeswijk, P. M.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The recent discovery of a supernova (SN 1998bw) seemingly associated with GRB~980425 adds a new twist to the decades-old debate over the origin of gamma-ray bursts. To investigate the possibility that some (or all) bursts are associated with supernovae, we performed a systematic search for temporal/angular correlations using catalogs of BATSE and BATSE/{\it Ulysses} burst locations. We find no associations with any of the precise BATSE/{\it Ulysses} locations, which allows us to conclude that the fraction of high-fluence gamma-ray bursts from known supernovae is small ($
description: Re-Submitted to Astrophysical Journal Letters, 1998 Jul. 24, 10 pages, 1 figure, 2 tables; (3) marc.kippen@msfc.nasa.gov
IκBα inhibits apoptosis at the outer mitochondrial membrane through a novel, NF-κB–independent, interaction with VDAC1
Creators: name: Pazarentzos, Evangelos
Publisher: name: Imperial College London
Year: 2012

description: The inducible transcription factor NF-κB is tightly regulated by the inhibitory IκB-family of proteins that associate with the transcription factor and act in response to stress stimuli. The best studied inhibitory protein is IκBα which resides in the cytosol where it retains NF-κB. Our study shows that IκBα also associates with the outer mitochondrial membrane (OMM) and exerts an unexpected novel anti-apoptotic function, independent of NF-κB inhibition. IκBα-/- cells become refractory to apoptosis when IκBα is specifically reconstituted at the OMM. We found that cancer cells with constitutively active NF-κB accumulate IκBα at the OMM and when its expression is down-regulated these cells are sensitised to apoptosis. At the OMM IκBα associates with VDAC1 and hexokinase II (HKII). Our findings show that IκBα inhibits the dissociation of HKII from VDAC1 and prevents Bax-mediated cytochrome c release. Deletion mutants of IκBα reveal a domain necessary for apoptosis inhibition that is different from the domain for NF-κB retention, thereby separating the two functions. These results reveal an unexpected activity of IκΒα in guarding the integrity of the OMM against apoptosis induction and open possibilities for more specific interference in diseases involving deregulated NF-κB.
The black hole mass distribution in early-type galaxies: cusps in HST photometry interpreted through adiabatic black hole growth
Creators: name: van der Marel, R. P.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The surface brightness profiles of early-type galaxies have central cusps. Two characteristic profile types are observed with HST: `core' profiles have a break at a resolved radius and logarithmic cusp slope gamma < 0.3 inside that radius; `power-law' profiles have no clear break and gamma > 0.3. With few exceptions, galaxies with M_V < -22 have core profiles, and galaxies with M_V > -20.5 have power-law profiles. Both profile types occur in galaxies with -22 < M_V < -20.5. We show that these results are consistent with the hypothesis that: (i) all early-type galaxies have black holes (BHs) that grew adiabatically in homogeneous isothermal cores; and (ii) these `progenitor' cores followed scaling relations similar to those of the fundamental plane. The models studied here are the ones first proposed by Young. Models with BH masses and progenitor cores that obey established scaling relations predict (at Virgo) that galaxies with M_V < -21.2 have core profiles and galaxies with M_V > -21.2 have power-law profiles. This reproduces both the sense and the absolute magnitude of the observed transition. Intrinsic scatter in BH and galaxy properties can explain why both types of galaxies are observed around the transition magnitude. The observed bimodality in cusp slopes may be due to a bimodality in M_bh/L, with rapidly rotating disky galaxies having larger M_bh/L than slowly rotating boxy galaxies. Application to individual galaxies with HST photometry yields a roughly linear correlation between BH mass and V-band galaxy luminosity, log M_bh = -1.83 + log L (solar units). This agrees with the average relation for nearby galaxies with kinematically determined BH masses, and also with predictions from quasar statistics (shortened abstract).
description: 41 pages, LaTeX, with 11 PostScript figures. Submitted to the Astronomical Journal. Postscript version also available from http://sol.stsci.edu/~marel/abstracts/abs_R23.html
Development of Composite Sponge Scaffolds Based on Carrageenan (CRG) and Cerium Oxide Nanoparticles (CeO2 NPs) for Hemostatic Applications
Creators: name: Kimia Alizadeh
name: Yasaman Dezvare
name: Shirin Kamyab
name: Jhaleh Amirian
name: Agnese Brangule
name: Dace Bandere
Publisher: name: Zenodo
Year: 2023
Subjects: carrageenan (CRG); cerium oxide (CeO2); nanoparticles (NPs); composite; antibacterial properties; hemostatic effect

description: In this study, a novel absorbable hemostatic agent was developed using carrageenan (CRG)as a natural polymer and cerium oxide nanoparticles (CeO2 NPs). CRG-CeO2-0.5 and CRG-CeO2-1composites were prepared by compositing CeO2 to CRG + CeO2 at a weight ratio of 0.5:100 and1:100, respectively. The physicochemical and structural properties of these compounds were studiedand compared with pristine CRG. Upon incorporation of CeO2 nanoparticles into the CRG matrix,significant reductions in hydrogel degradation were observed. In addition, it was noted that CRGCeO2exhibited better antibacterial and hemostatic properties than CRG hydrogel without CeO2NPs. The biocompatibility of the materials was tested using the NIH 3T3 cell line, and all sampleswere found to be nontoxic. Particularly, CRG-CeO2-1 demonstrated superior hemostatic effects,biocompatibility, and a lower degradation rate since more CeO2 NPs were present in the CRG matrix.Therefore, CRG-CeO2-1 has the potential to be used as a hemostatic agent and wound dressing.
Quantum Effects in Barrier Dynamics
Creators: name: Ankerhold, Joachim
name: Grabert, Hermann
Publisher: name: arXiv
Year: 1995
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: The dynamics near the top of a potential barrier is studied in the temperature region where quantum effects become important. The time evolution of the density matrix of a system that deviates initially from equilibrium in the vicinity of the barrier top but is in local equilibrium away from the barrier top is determined. Explicit results are given for a range of parameters where the nonequilibrium state is not affected by anharmonicities of the barrier potential except for the barrier height. In particular, for a system confined initially to one side of the barrier the relaxation to a quasi--stationary flux state is determined. The associated rate constant is evaluated and the relation to other rate formulas is discussed in detail.
description: 22 pages, 2 Postscript figures; in press (Chem. Phys.)
Reminiscences of Marion Dickerman, 1971
Publisher: name: Columbia University
Year: 2021
Subjects: Educators
New Deal, 1933-1939

description: World War I; friendship with Franklin and Eleanor Roosevelt; Todhunter School; Valkill Industries; Alfred E. Smith; opposition to Tammany Hall; Democratic conventions, 1924-32; reminiscences of Hyde Park, Campobello, Warm Springs; Eleanor Roosevelt: childhood, interest in women's suffrage and West Virginia mine workers, travels in Tennessee, Kentucky, Illinois; 74th Congress, 1935-36; visiting royalty; international conferences; death of President Roosevelt; of Mrs. Roosevelt; recollections of Roosevelt children, Louis Howe, Sumner Welles, Marguerite Le Hand, Harry Hopkins, and many others
Winds Can "Blow Up" AGN Accretion Disk Sizes
Creators: name: Sun, Mouyuan
name: Xue, Yongquan
name: Trump, Jonathan R.
name: Gu, Wei-Min
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Recent multi-band variability studies have revealed that active galactic nucleus (AGN) accretion disc sizes are generally larger than the predictions of the classical thin disc by a factor of $2\sim 3$. This hints at some missing key ingredient in the classical thin disc theory: here, we propose an accretion disc wind. For a given bolometric luminosity, in the outer part of an accretion disc, the effective temperature in the wind case is higher than that in the no-wind one; meanwhile, the radial temperature profile of the wind case is shallower than the no-wind one. In presence of winds, for a given band, blackbody emission from large radii can contribute more to the observed luminosity than the no-wind case. Therefore, the disc sizes of the wind case can be larger than those of the no-wind case. We demonstrate that a model with the accretion rate scaling as $\dot{M}_0 (R/R_{\mathrm{S}})^β$ (i.e., the accretion rate declines with decreasing radius due to winds) can match both the inter-band time lags and the spectral energy distribution of NGC 5548. Our model can also explain the inter-band time lags of other sources. Therefore, our model can help decipher current and future continuum reverberation mapping observations.
description: 7 pages, 4 figures, MNRAS in press
Rhamnus jujuba Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rhamnaceae
Rhamnus
Rhamnus jujuba

description: Rhamnus jujuba, spec. nov.
 8. Rhamnus aculeis solitariis recurvis, pedunculis aggregatis, floribus semidigynis, foliis retusis subtus tomentosis. Fl. zeyl. 89. *
 Jujuba indica spinosa, folio & fructu rotundo. Pluk. alm. 199. Raj. dendr.44.
 Habitat in India . ♄
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 194, DOI: 10.5281/zenodo.3931989