cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Graphulo: Linear Algebra Graph Kernels for NoSQL Databases
Creators: name: Gadepally, Vijay
name: Bolewski, Jake
name: Hook, Dan
name: Hutchison, Dylan
name: Miller, Ben
name: Kepner, Jeremy
Publisher: name: arXiv
Year: 2015
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: Databases (cs.DB)
subject: FOS: Computer and information sciences

description: Big data and the Internet of Things era continue to challenge computational systems. Several technology solutions such as NoSQL databases have been developed to deal with this challenge. In order to generate meaningful results from large datasets, analysts often use a graph representation which provides an intuitive way to work with the data. Graph vertices can represent users and events, and edges can represent the relationship between vertices. Graph algorithms are used to extract meaningful information from these very large graphs. At MIT, the Graphulo initiative is an effort to perform graph algorithms directly in NoSQL databases such as Apache Accumulo or SciDB, which have an inherently sparse data storage scheme. Sparse matrix operations have a history of efficient implementations and the Graph Basic Linear Algebra Subprogram (GraphBLAS) community has developed a set of key kernels that can be used to develop efficient linear algebra operations. However, in order to use the GraphBLAS kernels, it is important that common graph algorithms be recast using the linear algebra building blocks. In this article, we look at common classes of graph algorithms and recast them into linear algebra operations using the GraphBLAS building blocks.
description: 10 pages
title: Cystic neutrophilic granulomatous mastitis: An underdiagnosed entity recently discovered
Creators: name: Ruiz, Mónica
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Breast
subject: CT
subject: Audit and standards
subject: Acute

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: The aim of this article is to discuss the spectrum of the anomaly by analyzing various case reports, presenting the clinical manifestations and differential diagnosis with emphasis on imaging findings (including mammography, ultrasound and MRI) and...
Minimal-length quantum field theory: a first-principle approach
Creators: name: Bosso, Pasquale
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Phenomenological models of quantum gravity often consider the existence of some form of minimal length. This feature is commonly described in the context of quantum mechanics and using the corresponding formalism and techniques. Although few attempts at a quantum field-theoretical description of a minimal length has been proposed, they are rather the exception and there is no general agreement on the correct one. Here, using the quantum-mechanical model as a guidance, we propose a first-principle definition of a quantum field theory including a minimal length. Specifically, we propose a two-step procedure, by first describing the quantum-mechanical models as a classical field theory and subsequently quantizing it. We are thus able to provide a foundation for further exploration of the implications of a minimal length in quantum field theory.
description: 24 pages, 2 figures, 3 appendices
(401701) Charles Cowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Teaching Digital Accessibility in Computing Education: Views of Educators in India
Creators: name: Parthasarathy
name: Swaroop
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: In recent years, there has been rising interest from both governments and private industry in developing software that is accessible to all, including people with disabilities. However, the computer science (CS) courses that ought to prepare future professionals to develop such accessible software hardly cover topics related to accessibility. While there is growing literature on incorporating accessibility topics in computing education in the West, there is little work on this in the Global South, particularly in India, which has a large number of computing students and software professionals. In this replication report, we present (A) our findings from a replication of surveys used in the US and Switzerland on who teaches accessibility and barriers to teaching accessibility and (B) a qualitative analysis of perceptions of CS faculty in India about digital accessibility and teaching accessibility. Our study corroborates the findings of the earlier surveys: very few CS faculty teach accessibility, and the top barriers they perceive are the same. The qualitative analysis further reveals that the faculty in India need training on accessibility concepts and disabilities sensitization, and exposure to existing and ongoing CS education research and pedagogies. In light of these findings, we present recommendations aimed at addressing these challenges and enhancing the integration of accessibility into computing education.
description: Accepted to be published in proceedings of the ACM International Conference on Computing Education Research (ICER) 2024
Rico: extended TIAGo robot towards up-to-date social and assistive robot usage scenarios
Creators: name: Winiarski, Tomasz
name: Dudek, Wojciech
name: Giełdowski, Daniel
Publisher: name: arXiv
Year: 2024
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Social and assistive robotics have vastly increased in popularity in recent years. Due to the wide range of usage, robots executing such tasks must be highly reliable and possess enough functions to satisfy multiple scenarios. This article describes a mobile, artificial intelligence-driven, robotic platform Rico. Its prior usage in similar scenarios, the number of its capabilities, and the experiments it presented should qualify it as a proper arm-less platform for social and assistive circumstances.
description: PP-RAI 2024, 5th Polish Conference on Artificial Intelligence, 18-20.04.2024 Warsaw, Poland
An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A
Creators: name: Hahn, Klaus M.
name: Snider, William D.
name: Berrios, Janet
name: Zylka, Mark J.
name: Newbern, Jason M.
name: Yi, Jason J.
name: Philpot, Benjamin D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Deletion of UBE3A causes the neurodevelopmental disorder Angelman syndrome (AS) while duplication or triplication of UBE3A is linked to autism. These genetic findings suggest that the ubiquitin ligase activity of UBE3A must be tightly maintained to promote normal brain development. Here, we found that protein kinase A (PKA) phosphorylates UBE3A in a region outside the catalytic domain, at residue T485, and inhibits UBE3A activity towards itself and other substrates. A de novo autism-linked missense mutation disrupts this phosphorylation site, causing enhanced UBE3A activity in vitro, enhanced substrate turnover in patient-derived cells, and excessive dendritic spine development in the brain. Our study identifies PKA as an upstream regulator of UBE3A activity, and shows that an autism-linked mutation disrupts this phosphorylation control. Moreover, our findings implicate excessive UBE3A activity and the resulting synaptic dysfunction to autism pathogenesis.
Traveling cluster pairs in a system of phase oscillators with positive and negative couplings under a periodic driving field
Creators: name: Choi, Jungzae
name: Choi, M. Y.
name: Chung, Moon Sung
name: Yoon, Byung-Gook
Publisher: name: arXiv
Year: 2015
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences

description: We investigate numerically the clustering behavior of a system of phase oscillators with positive and negative couplings under a periodic external driving field with a bimodal distribution of driving phases. The phase distribution and the mean speed of the traveling state, as well as the order parameter for synchronization, are computed as the driving amplitude is varied. We observe that the periodically-driven system can also host traveling states for parameters in the same range as those for the case of a system without a driving field. The traveling speed is found to depend non-monotonically on the driving amplitude. In particular, oscillators divide into four clusters and move in pairs. Further, depending on the driving amplitude, two kinds of traveling mode arise: pairs of clusters traveling in the same direction (symmetric mode) and in opposite directions (antisymmetric mode). In the latter case (antisymmetric traveling mode), the average phase speed of the whole system apparently vanishes. A phenomenological argument for such behavior is given.
description: 5 pages, 7 figures. arXiv admin note: text overlap with arXiv:1408.2894 by other authors
Decay of $B^\pm \to τ^\pm +$ "missing momentum" and direct measurement of the mixing parameter $U_{τN}$
Creators: name: Cvetič, Gorazd
name: Kim, C. S.
name: Kwon, Y. -J.
name: Yook, Y. -M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We derive the decay widths for the leptonic decays of heavy charged pseudoscalars to massive sterile neutrinos, $M^{\pm} \to \ell^{\pm} + N$, within the frameworks involving the Standard Model and two-Higgs doublets (type II). We then apply the result to $B^\pm \to τ^\pm +$ "missing momentum" of the Belle/BaBar experimental results, in order to measure directly the relevant parameter space, including the mixing parameter $U_{τN}$.
description: 19 pages, 6 figures, published at Phys. Rev. D
title: Three-dimensional CT texture analysis combined with machine learning can distinguish pancreatic ductal adenocarcinomas from neuroendocrine tumors and predict tumor grades
Creators: name: Budai, Bettina
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Artificial Intelligence
subject: Oncology
subject: Pancreas
subject: CT
subject: Computer Applications-Detection, diagnosis
subject: Cancer
subject: Neoplasia
subject: Tissue characterisation

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Pancreatic cancer is the 14 th most common cancer in the world and the 7 th most common cause of death by cancer [1]. Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignant tumors, as it has a 5-year survival rate of only...
GPFS AFM as a transparent cache for Ceph Object Storage
Creators: name: Sapunenko, Vladimir
name: Fornari, Federico
Publisher: name: Zenodo
Year: 2023

description: At INFN-CNAF, an R&D activity based on the implementation of a transparent GPFS cache connected to Ceph Object Gateway has been carried out recently. The integration between GPFS and external object storage systems has been made possible by a new GPFS functionality called “Active File Management to Cloud Object Storage”. In general, this solution consists in a GPFS fileset acting as a cache that provides end users with POSIX access to their data located anywhere in the cloud. In our (Tier1) use case we are investigating the possibility to reduce usage of proprietary software (GPFS) placing major part of experiments’ data into object storage but keeping at the same time the possibility to provide POSIX access to this data.
 A set of suitable tests has been executed in order to verify the level of reliability and performance provided by the integration between GPFS and Ceph RADOS Gateway, yielding positive results.
 Considering that IBM moved its licensing model from "socket" to "capacity" and that we expect significant growth of storage space usage in the next future, such an approach could help in saving important amount of funds just on software licenses. This presentation was given in the ICT Infrastructures and Distributed Computing track of INFN CCR Workshop 2023.
title: MDCT evaluation in EVAR planning
Creators: name: Gandileva, Venelina
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Arteries / Aorta
subject: Cardiovascular system
subject: Vascular
subject: CT
subject: CT-Angiography
subject: Computer Applications-3D
subject: Contrast agent-intravenous
subject: Aneurysms
subject: Arteriosclerosis

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To describe the correct CT protocol to provide the relevant information for EVAR planning. To illustrate all measurements required in the preprocedural planning. To describe comprehensive...
$π$ mode lasing in the non-Hermitian Floquet topological system
Creators: name: Shen, Shuang
name: Kartashov, Yaroslav V.
name: Li, Yongdong
name: Cao, Meng
name: Zhang, Yiqi
Publisher: name: arXiv
Year: 2024
Subjects: subject: Optics (physics.optics)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: $π$ modes are unique topological edge states appearing in Floquet systems with periodic modulations of the underlying lattice structure in evolution variable, such as dynamically modulated Su-Schrieffer-Heeger (SSH) lattices. These edge states are anomalous states usually appearing between Floquet replicas of the same band, even if standard topological index remains zero for this band. While linear and nonlinear $π$ modes were observed in conservative systems, they have never been studied in nonlinear regime in the non-Hermitian systems with structured gain and losses. Here we show that SSH waveguide array with periodically oscillating waveguide positions in propagation direction and with parity-time symmetric refractive index landscape, can support $π$ modes that are damped or amplified at different ends of the array. By including nonlinearity and nonlinear absorption into our continuous system, we achieve stable lasing in $π$ mode at one end of the array. The representative feature of this system is that lasing in it is thresholdless and it occurs even at low gain-loss amplitudes. The degree of localization of lasing $π$ modes can be flexibly controlled by the amplitude of transverse waveguide oscillations. This work therefore introduces a new type of topological Floquet laser and a route to manipulation of $π$ modes by structured gain and losses.
description: 9 pages, 3 figures, to appear in APL Photonics
title: Ultrasound guided Fine needle aspiration versus non-aspiration techniques in evaluation of solid thyroid nodules
Creators: name: Heidar, Mustafa
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Head and neck
subject: Interventional non-vascular
subject: Thyroid / Parathyroids
subject: Ultrasound
subject: Biopsy
subject: Technical aspects
subject: Pathology

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Thyroid nodules are a common pathology of the endocrine system, with an estimated prevalence of about 34.2%. [1] Many techniques were developed for evaluation of the thyroid nodules, ultrasound (US)-guided fine needle cytology (FNC) is an accurate,...
Governing for innovation in horizontal service cooperations
Creators: name: Steinicke, Silvia
name: Wallenburg, Carl Marcus
name: Schmoltzi, Christina
Publisher: name: Technische Universität Berlin
Year: 2012
Subjects: subject: 330 Wirtschaft
subject: co-operation
subject: innovation
subject: survey
subject: service operations
subject: organizational effectiveness
subject: horizontal management

description: Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
description: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
description: Purpose – The purpose of this study is to provide insights into the role of governance mechanisms in fostering innovativeness in horizontal service cooperations. Design/methodology/approach – Data were collected from 225 horizontal service cooperations in the logistics industry via an online survey. Structural equation modeling was used to analyze the empirical data. Findings – The choice of governance measures helps to improve the innovativeness of service cooperations. The use of formalization and balanced mutual influence, combined with cultural similarity provides the basis for the development of new or enhanced services within the cooperation. In contexts that build on equity-based contracts, innovativeness is driven by the degree of mutual influence among partners. Research limitations/implications – Empirical data were collected in a single industry (logistics) and in a single country (Germany). A confirmation of the results in different service settings is therefore encouraged. Practical implications – This research emphasizes the importance of governance in facilitating innovation in service cooperations. By applying the right governance mechanisms in possible settings of co-opetition, managers can foster coordination and the exchange of knowledge and diminish opportunistic behavior among parties. Originality/value – The research is extended by developing a model based on the knowledge of service innovation, cooperation performance and governance mechanisms and by empirically testing this model.
title: Moving Towards Whole Life Environmental Sustainability: A case study of social housing projects in Europe
Creators: name: Polycarpou, Kyriacos
Publisher: name: The Open University
Year: 2025

description: This thesis is written at a time of rapid change for the construction sector as it moves towards a more sustainable future. European standards for the sustainability of construction works were published in 2011 and 2012, and since then the use of Life Cycle Assessment (LCA) to measure and reduce whole life environmental impacts of buildings has gradually become more common. New requirements for ‘sustainable’ and ‘low carbon’ or even ‘zero carbon’ developments have been introduced, and recently some nation states have introduced regulation requiring the calculation of whole life, as well as operational, environmental impacts. The aspirations towards more sustainable construction suggested by the changing policies and standards have not, however, necessarily been matched in practice; the picture is also very different in different countries, even within the common European frameworks.

This thesis considers what is happening in three contrasting countries of Sweden, Cyprus and the UK, and develops case studies of construction projects to explore how decisions are being made in practice and why. The focus is on social housing projects, as these have relative equivalence across the three countries, and are also a high-volume, low-cost building type. The aim is to understand how to better implement sustainability aspirations and reduce carbon emissions from standard construction projects, rather than just environmental exemplars and high-cost developments.

Results show that currently LCA is seldom used in such projects. It is also found that the national context has a significant impact on how decisions are made, and that individuals, tools and artefacts, regulatory requirements, and organisational structures, can all affect the potential outcome of a building project. The thesis concludes that understanding construction projects as part of a complex socio-technical system is essential in order to effectively implement LCA and reduce whole life carbon emission.
First passage times in integrate-and-fire neurons with stochastic thresholds
Creators: name: Braun, Wilhelm
name: Matthews, Paul C.
name: Thul, Rüdiger
Publisher: name: arXiv
Year: 2015
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: Probability (math.PR)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We consider a leaky integrate-and-fire neuron with deterministic subthreshold dynamics and a firing threshold that evolves as an Ornstein-Uhlenbeck process. The formulation of this minimal model is motivated by the experimentally observed widespread variation of neural firing thresholds. We show numerically that the mean first passage time can depend non-monotonically on the noise amplitude. For sufficiently large values of the correlation time of the stochastic threshold the mean first passage time is maximal for non-vanishing noise. We provide an explanation for this effect by analytically transforming the original model into a first passage time problem for Brownian motion. This transformation also allows for a perturbative calculation of the first passage time histograms. In turn this provides quantitative insights into the mechanisms that lead to the non-monotonic behaviour of the mean first passage time. The perturbation expansion is in excellent agreement with direct numerical simulations. The approach developed here can be applied to any deterministic subthreshold dynamics and any Gauss-Markov processes for the firing threshold. This opens up the possibility to incorporate biophysically detailed components into the subthreshold dynamics, rendering our approach a powerful framework that sits between traditional integrate-and-fire models and complex mechanistic descriptions of neural dynamics.
description: 8 pages, 7 figures. Accepted for publication in Physical Review E
Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity
Creators: name: Kaplan, Mark H.
name: Swanson, Michael D.
name: Gabius, Hans Joachim
name: Goldstein, Irwin J.
name: Smee, Donald F.
name: Schols, Dominique
name: Tarbet, E. Bart
name: King, Steven
name: Xue, Yi
name: Hoffmann, Hans Heinrich
name: Meagher, Jennifer L.
name: Garcia, J. Victor
name: Boudreaux, Daniel M.
name: Murphy, Paul V.
name: Rice, Charles M.
name: Oscarson, Stefan
name: Salmon, Loïc
name: De La Fuente, Cynthia
name: Winter, Harry C.
name: Markovitz, David M.
name: Roy, René
name: Stuckey, Jeanne A.
name: André, Sabine
name: Chugh, Jeetender
name: Hurst, Brett L.
name: Al-Hashimi, Hashim M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: A key effector route of the Sugar Code involves lectins that exert crucial regulatory controls by targeting distinct cellular glycans. We demonstrate that a single amino acid substitution in a banana lectin, replacing histidine 84 with a threonine, significantly reduces its mitogenicity while preserving its broad-spectrum antiviral potency. X-ray crystallography, NMR spectroscopy, and glycocluster assays reveal that loss of mitogenicity is strongly correlated with loss of pi-pi stacking between aromatic amino acids H84 and Y83, which removes a wall separating two carbohydrate binding sites, thus diminishing multivalent interactions. On the other hand, monovalent interactions and antiviral activity are preserved by retaining other wild-type conformational features and possibly through unique contacts involving the T84 side chain. Through such fine-tuning, target selection and downstream effects of a lectin can be modulated so as to knock down one activity while preserving another, thus providing tools for therapeutics and for understanding the Sugar Code.
Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo
Creators: name: Chen, Eric R.
name: Voight, Benjamin F.
name: Emmett, Matthew J.
name: Civelek, Mete
name: Dispirito, Joanna R.
name: Safabakhsh, Pegah
name: Steger, David J.
name: Soccio, Raymond E.
name: Won, Kyoung Jae
name: Fang, Bin
name: Lim, Hee Woong
name: Rajapurkar, Satyajit R.
name: Briggs, Erika R.
name: Wu, Ying
name: Everett, Logan J.
name: Lazar, Mitchell A.
name: Marinis, Jill M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: SNPs affecting disease risk often reside in non-coding genomic regions. Here, we show that SNPs are highly enriched at mouse strain-selective adipose tissue binding sites for PPARγ, a nuclear receptor for anti-diabetic drugs. Many such SNPs alter binding motifs for PPARγ or cooperating factors and functionally regulate nearby genes whose expression is strain selective and imbalanced in heterozygous F1 mice. Moreover, genetically determined binding of PPARγ accounts for mouse strain-specific transcriptional effects of TZD drugs, providing proof of concept for personalized medicine related to nuclear receptor genomic occupancy. In human fat, motif-altering SNPs cause differential PPARγ binding, provide a molecular mechanism for some expression quantitative trait loci, and are risk factors for dysmetabolic traits in genome-wide association studies. One PPARγ motif-altering SNP is associated with HDL levels and other metabolic syndrome parameters. Thus, natural genetic variation in PPARγ genomic occupancy determines individual disease risk and drug response.
(401702) Edward Cowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Phase-Separated Charge Order and Twinning Across Length Scales in CsV$_3$Sb$_5$
Creators: name: Plumb, Jayden
name: Salinas, Andrea Capa
name: Mallayya, Krishnanand
name: Kisiel, Elliot
name: Carneiro, Fellipe B.
name: Gomez, Reina
name: Pokharel, Ganesh
name: Kim, Eun-Ah
name: Sarker, Suchismita
name: Islam, Zahirul
name: Daly, Sam
name: Wilson, Stephen D.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We present X-ray scattering studies resolving structural twinning and phase separation in the charge density wave (CDW) state of the kagome superconductor CsV$_3$Sb$_5$. The three-dimensional CDW state in CsV$_3$Sb$_5$ is reported to form a complex superposition of Star of David (SoD) or Tri-Hexagonal (TrH) patterns of distortion within its kagome planes, but the out-of-plane stacking is marked by metastability. In order to resolve the impact of this metastability, we present reciprocal space mapping and real-space images of CsV$_3$Sb$_5$ collected across multiple length scales using temperature-dependent high-dynamic range mapping (HDRM) and dark-field X-ray microscopy (DFXM). The experimental data provide evidence for a rich microstructure that forms in the CDW state. Data evidence metastability in the formation of $2\times 2\times 4$ and $2\times 2\times 2$ CDW supercells dependent on thermal history and mechanical deformation. We further directly resolve the real space phase segregation of both supercells as well as a real-space, structural twinning driven by the broken rotational symmetry of the CDW state. Our combined results provide insights into the role of microstructure and twinning in experiments probing the electronic properties of CsV$_3$Sb$_5$ where rotational symmetry is broken by the three-dimensional charge density wave order but locally preserved for any single kagome layer.
description: 12 pages, 9 figures
title: Protocol from the angiosuite for the selection, treatment and follow-up of patients with adhesive capsulitis candidate for transarterial embolization.
Creators: name: Perez Rodriguez, María
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Extremities
subject: Interventional vascular
subject: Musculoskeletal system
subject: Catheter arteriography
subject: Embolisation
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: The aim of this project is exposing our methodology treating patients with adhesive capsulitis, for an adequate selection, preparation and monitoring of the...
Novel functional imaging approaches for investigating brain plasticity in multiple sclerosis and Parkinson?s disease: from research to clinical applications
Creators: name: BOMMARITO, GIULIA
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: Neuronal plasticity, as the capacity of the brain to respond to external demands or to injury, has emerged as a crucial mechanism to preserve, at least in part, an adequate behavioral functioning after an injury and as the process underlying improvements in disability during rehabilitation. Brain plasticity can be detected with both structural and functional magnetic resonance imaging and more and more processing techniques have been developed to better capture the occurring changes and to better define the potential plasticity. Gait and balance are affected in patients with multiple sclerosis since the early stages of the disease with sensory deficits playing a major role in determining both balance and gait impairment. Moreover, gait disorders are one of the major causes of disability in patients with Parkinson?s disease, in particular if suffering from freezing of gait. With this work we aimed at i) investigating the functional reorganization occurring in multiple sclerosis at both early and late stages of the disease, ii) characterizing the functional pattern underlying sensory impairment in patients with early multiple sclerosis and iii) verifying the neural correlates of action observation of gait in patients with Parkinson?s disease. These different studies fit into a larger framework where neuroimaging techniques, in particular functional imaging, would support the clinicians in identifying tailored rehabilitation treatments and the patients who would better benefit from them. We found that patients with early multiple sclerosis showed a higher brain functional flexibility, expressed in terms of blood oxygen level dependent signal variability, which correlated to clinical disability, representing a possible compensatory mechanism. In patients with early multiple sclerosis we also observed subtle position sense deficits, not detectable with a standard neurological examination, and which affected still standing balance. Moreover, these deficits were related to a structural damage at the level of the corpus callosum and to functional activity patterns mainly involving the frontoparietal regions. On the contrary, patients with multiple sclerosis at the progressive stages presented with more subtle changes in the resting state functional connectivity which, nonetheless, were related to clinical disability. Lastly, the presence of freezing of gait in patients with Parkinson disease influenced the neural activation underpinning the action observation of walking. Altogether, these results offer an better insight into the pathophysiological mechanisms underlying disability in patients with multiple sclerosis and constitute a groundwork for the enhancement of rehabilitation protocols to improve gait and balance in both multiple sclerosis and Parkinson?s disease, supporting the embracing of new strategies such as sensory integration and action observation training.
Some Torsional Local Models of Heterotic Strings
Creators: name: Fei, Teng
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We construct solutions to the Strominger system on a class of noncompact Calabi-Yau 3-folds. These spaces include $\mathbb{C}^3$ and resolved conifold $\mathcal{O}(-1,-1)$ as special examples.
description: 18 pages, comments are welcome! Updates in v2: References added, a discussion of extremal balanced metrics is included
(401698) Frances Isabella [Sturge]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The TANDEM National Research and Education Network Survey (French)
Creators: name: Taylor, Simon J E
name: Keshefi, Armin
name: Abbott, Pamela
Publisher: name: Sci-GaIA Open Access Repository
Year: 2016

description: This is the paper version of the online survey done to assess NREN service needs by end users as paper of the TANDEM project (tandem-wacren.eu).
title: Maybe it’s not cancer: Infectious diseases mimicking malignancies in multiple systems
Creators: name: Mamere, Augusto
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: Neuroradiology brain
subject: Thorax
subject: CT
subject: MR
subject: Diagnostic procedure
subject: Infection

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: - To discuss epidemiological and clinical findings of infectious diseases that can mimic neoplasms in various systems. - To describe and discuss imaging findings in a series of cases. - To discuss the main differential diagnoses of each...
Product Binding Enforces the Genomic Specificity of a Yeast Polycomb Repressive Complex
Creators: name: Dumesic, Phillip A.
name: Shanle, Erin K.
name: Yates, John R.
name: Moresco, James J.
name: Coyle, Scott M.
name: Strahl, Brian D.
name: Pack, Lindsey R.
name: Madhani, Hiten D.
name: Homer, Christina M.
name: Fujimori, Danica G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: We characterize the Polycomb system that assembles repressive subtelomeric domains of H3K27 methylation (H3K27me) in the yeast Cryptococcus neoformans. Purification of this PRC2-like protein complex reveals orthologs of animal PRC2 components as well as a chromodomain-containing subunit, Ccc1, which recognizes H3K27me. Whereas removal of either the EZH or EED ortholog eliminates H3K27me, disruption of mark recognition by Ccc1 causes H3K27me to redistribute. Strikingly, the resulting pattern of H3K27me coincides with domains of heterochromatin marked by H3K9me. Indeed, additional removal of the C. neoformans H3K9 methyltransferase Clr4 results in loss of both H3K9me and the redistributed H3K27me marks. These findings indicate that the anchoring of a chromatin-modifying complex to its product suppresses its attraction to a different chromatin type, explaining how enzymes that act on histones, which often harbor product recognition modules, may deposit distinct chromatin domains despite sharing a highly abundant and largely identical substrate—the nucleosome.
title: Deep neck spaces: an anatomical and pathological imaging approach
Creators: name: Mamere, Augusto
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Head and neck
subject: CT
subject: MR
subject: Diagnostic procedure
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: - To review and discuss the deep neck spaces anatomy and their main pathologies. - To describe the main imaging findings in a series of cases. - To discuss the main differential diagnoses of each...
A Structured Prediction Approach to Robot Imitation Learning
Creators: name: DUAN, ANQING
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: This thesis is primarily focused on movement primitives-based imitation learn- ing, within the context of robot programming by demonstration. Specifically, the imitation problem is tackled from a supervised-learning perspective. Therefore, it allows us to resort to theoretical tools from structured prediction, which can handle data-sets with complex structures. The first part of the thesis provides an overall background, in which we overview state-of-the-art imitation learning algorithms as well as discuss relevant technical tools. We formally introduce our contribution in part II. Our algorithm is not only capable of learning usual Euclidean trajectories (Chapter 7), but also trajectories lying on some manifold (Chapter 8). The capability of adapting manifold trajectories distinguishes our approach from other imitation learning algorithms. Subsequently, we provide a few extensions to augment our approach, including trajectory refinement by policy search (Chapter 10), imitation learning with constraints (Chapter 11), and probabilistic trajectory transfer (Chapter 12). We then conclude the thesis in the epilogue.
title: Adductor Longus Muscle tear: A cause of Athletic pubalgia! Radiological Evaluation with imaging features
Creators: name: Sajid, Sadia
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Anatomy
subject: Extremities
subject: Musculoskeletal system
subject: MR
subject: PACS
subject: Ultrasound
subject: Education
subject: Imaging sequences
subject: Statistics
subject: FOS: Mathematics
subject: Athletic injuries
subject: Education and training
subject: Trauma

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: 1. To describe MR findings of different patterns of adductor longus muscle injuries. 2. To assess the associated abnormalities, including hematoma and other muscular...
Clustering Analysis of Website Usage on Twitter during the COVID-19 Pandemic
Creators: name: Cruickshank, Iain
Publisher: name: figshare
Year: 2020
Subjects: subject: 80602 Computer-Human Interaction
subject: FOS: Psychology
subject: Applied Computer Science

description: Top 50,000 most-used URLs in COVID-19 Twitter along with their domain labels, cluster labels, and Tweet usage numbers. Data is from SNMAM 2020 Conference paper entitled "Clustering Analysis of Website Usage on Twitter during the COVID-19 Pandemic"
Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors
Creators: name: Druz, Aliaksandr
name: Scheid, Johannes F.
name: Burton, Dennis R.
name: West, Anthony P.
name: Zhou, Tongqing
name: Shapiro, Lawrence
name: Casazza, Joseph P.
name: Srivatsan, Sanjay
name: Georgiev, Ivelin S.
name: Lanzavecchia, Antonio
name: Tran, Lillian
name: Luongo, Timothy S.
name: Zheng, Anqi
name: Longo, Nancy S.
name: Yang, Yongping
name: Louder, Mark K.
name: Koff, Wayne C.
name: O'Dell, Sijy
name: Ernandes, Michael J.
name: Mascola, John R.
name: Weiss, Robin A.
name: Lingwood, Daniel
name: Wu, Xueling
name: Yang, An Suei
name: Gray, Matthew D.
name: Cohen, Myron S.
name: Kwong, Peter D.
name: Chen, Lei
name: Sattentau, Quentin J.
name: Yang, Zhongjia
name: Bjorkman, Pamela J.
name: McKee, Krisha
name: Peng, Hung Pin
name: Doria-Rose, Nicole A.
name: Schmidt, Stephen D.
name: Stamatatos, Leonidas
name: Mullikin, James C.
name: Kong, Rui
name: Connors, Mark
name: Bailer, Robert T.
name: Corti, Davide
name: Moquin, Stephanie
name: Kirys, Tatsiana
name: Nussenzweig, Michel C.
name: Lynch, Rebecca M.
name: Pancera, Marie
name: Soto, Cinque
name: Haynes, Barton F.
name: Gindin, Tatyana
name: Zhang, Baoshan
name: Acharya, Priyamvada
name: Joyce, M. Gordon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The site on the HIV-1 gp120 glycoprotein that binds the CD4 receptor is recognized by broadly reactive antibodies, several of which neutralize over 90% of HIV-1 strains. To understand how antibodies achieve such neutralization, we isolated CD4-binding-site (CD4bs) antibodies and analyzed 16 co-crystal structures –8 determined here– of CD4bs antibodies from 14 donors. The 16 antibodies segregated by recognition mode and developmental ontogeny into two types: CDR H3-dominated and VH-gene-restricted. Both could achieve greater than 80% neutralization breadth, and both could develop in the same donor. Although paratope chemistries differed, all 16 gp120-CD4bs antibody complexes showed geometric similarity, with antibody-neutralization breadth correlating with antibody-angle of approach relative to the most effective antibody of each type. The repertoire for effective recognition of the CD4 supersite thus comprises antibodies with distinct paratopes arrayed about two optimal geometric orientations, one achieved by CDR H3 ontogenies and the other achieved by VH-gene-restricted ontogenies.
title: Starting a CT guided Robotic Interventional Oncology practice
Creators: name: Johnston, Edward
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Interventional non-vascular
subject: Liver
subject: Oncology
subject: CT
subject: Ablation procedures
subject: Biopsy
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: The objective in non-vascular, CT-guided Interventional Radiology (IR) is to accurately place a needle from a percutaneous entry point to a target via a safe path for diagnostic or therapeutic purposes. Conventional practice involves planning needle...
Expression of IL12 and IL23 receptors and cytokines in Chronic Lymphocytic Leukemia and normal B cells
Creators: name: CARDILLO, MARTINA
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: The mechanisms of clonal expansion of CLL are only partially understood. Several interactions of neoplastic cells with accessory cells and cytokines potentially sustaining neoplastic B cell clone survival and proliferation have been described. Recently, a paracrine/autocrine loop has been reported, involving the upregulation of the IL23R complex and IL23 secretion by CLL cells. This loop drives CLL cell clonal expansion in vitro and in xenografted NSG mice. Furthermore, in situ observations on tissue sections demonstrate that infiltrating IL23 secreting CLL cells interact with macrophages and CD40L expressing T cells. Although inducible in vitro by co-culturing CLL cells with T cells or CD40L expressing cells, the IL23 loop is not observed following stimulation of CLL cells via surface Ig or contact with nurse like cells or bone marrow stromal cells. In this study, we investigated whether the IL23 loop could be induced following Toll-like receptor 9 (TLR9) engagement which influences leukemic cell survival, activation proliferation albeit in a heterogeneous manner. In addition, we explored the possible existence of an autocrine/paracrine loop mediated by IL12 which shares similarities and surface receptors with IL23 although with a likely opposite outcome in term of the possibility to sustain leukemic cell growth . IL23R and IL12R complexes (IL23R/IL12R?1, IL12?2/IL12R?1) expression were evaluated by flow-cytometry following stimulation with CpG oligodeoxynucleotide (ODN) that binds the TLR9 on CLL, showing that CLL cells are able to express the IL23R complex on membrane and, at lower extent, the IL12R complex. These receptors were assessed also in normal B cells by flow cytometry after 72h of stimulation with CpG and CpG+IL15. In this setting, normal B cells were less capable of IL23R complex expression compared to CLL cells. A further striking difference observed was related to the limited expression of IL12R�2 receptor chain in stimulated CLL cells compared to normal B cells. Supernatants of CLL cells and normal B cells were both tested for the production of these cytokines after stimulation. The results showed a low level of IL23p19 secretion for both CLL cells and normal B cells, which is significant after CD40L stimulation (used as positive control), and a higher production of IL12p70 which is more pronounced in normal B cells compared to CLL. In another series of tests, CLL cells were stimulated with CpG for 72h, and subsequently exposed to IL12 or IL23. Exposure to IL12 and IL23 induced the expression of pSTAT1 and pSTAT3. Collectively our data corroborate the notion that IL23R complex act as a pro-survival factor for CLL cells. In contrast, the restricted IL12R complex expression in CLL cells compared to normal B cells indicated that the suppression of the expression of this receptor may favor the survival of the leukemic clones. The possibility of a reciprocal competition of the shared receptor chains is discussed.
title: Don’t be afraid to use Contrast Enhanced Ultrasound in the transplant kidney. It works. And it is safe.
Creators: name: Cokkinos, Demosthenes
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Kidney
subject: Ultrasound
subject: Contrast agent-intravenous
subject: Grafts

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To review indications of Contrast enhanced ultrasound (CEUS) in transplant kidneys. To outline CEUS advantages. To explain why it is safe to perform CEUS in transplant patients. To show cases in which CEUS improves baseline US findings, answering...