cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Grundlagen der Pultrusion zur Fertigung von FV-Bauteilen für die Anforderungen der automobilen Großserie = Fundamentals of the Pultrusion Process for Production of FRP Components for the Requirements of Automotive Large-scale Production
Creators: name: Krebs, Dominic
Publisher: name: Karlsruhe
Year: 2018
Subjects: Pultrusion
CFK
Großserie
FV-Bauteile
Automobil

description: Im Zuge der Weiterentwicklung von Werkstoffen und Fertigungstechnologien für den Automobilbau steigt der Bedarf nach kosteneffizienten und produktiven Verfahren zur Herstellung kohlenstofffaserverstärkter Kunststoffbauteile. Das Pultrusionsverfahren bietet die geforderte Großserienfähigkeit bei gleichzeitig geringen Fertigungskosten durch einen kontinuierlichen Prozessverlauf. Um alle Potentiale dieses Verfahrens nutzen zu können, ist ein umfassendes Prozessverständnis erforderlich.
Zur Qualifizierung des Pultrusionsverfahrens für den Einsatz in der automobilen Großserie werden in dieser Arbeit die notwendigen Kenntnisse über Wechselwirkungen im Prozess und das Wissen um die Auswirkung einzelner Parameter auf grundlegende Bauteileigenschaften wie Steifigkeit und Festigkeit sowie Ausprägung weiterer Merkmale, wie z.B. Reinharzbereiche und Falten, erarbeitet.
Ausgehend von einer gesamthaften Systemanalyse, unter Verwendung der Ishikawa-Methode und mehrstufigen Plausibilisierungen, wird eine repräsentative Parametersammlung erarbeitet. Mittels einer Intensitäts-Beziehungsmatrix werden diese Parameter quantitativ bewertet und theoretische Wechselwirkungen erarbeitet. Die im Zuge der Systemanalyse ermittelten und gewichteten Parameter bilden die Grundlage zur experimentellen Überprüfung der Wirkzusammenhänge mit Hilfe der Methode der statistischen Versuchsplanung. Umfassende Vorversuche definieren die Parameterstufen des Versuchsplans mit den Parametern Formfüllgrad, Abzugsgeschwindigkeit, Kammertemperierung und Temperaturprofil. Die Injektionstechnologie für Kohlenstofffasern in einer Epoxid-Matrix mit Gelegeverstärkung bildet das Zielsystem.
Um die Bauteilqualität überhaupt messbar zu machen, wird eine mehrstufige Prüfmethodik entwickelt und angewandt. Neben Zielgrößen wie mechanische Eigenschaften, Geometrie und Imprägnierqualität wird die Merkmalsausprägung detailliert untersucht und in Form eines Merkmalskataloges messbar gemacht. Mit Hilfe des Merkmalskataloges ist es nun möglich, die Bauteilqualität bezüglich lokaler Inhomogenitäten zu beschreiben und Abweichungen vom Sollzustand einheitlich zu charakterisieren. Die umfangreiche Parameterstudie bestätigt die theoretischen Ergebnisse der Systemanalyse. Ausgewertet werden die Prozessdaten, die Bemusterung der produzierten Profile nach dem erarbeiteten Merkmalskatalog, die physikalisch-chemischen und thermischen Untersuchungsmethoden, die mikrostrukturellen Untersuchungsmethoden und die mechanischen Prüfungen.
Sparse Direct Solution Methods for Capacitive Extraction Problems on Closely-Spaced Geometries with High Aspect Ratios
Creators: name: Chang, Chee Kean
Publisher: name: University of Kentucky Libraries
Year: 2017
Subjects: subject: Electromagnetics and Photonics

description: The method of moment (MoM) [1] is a widely used method in electromagnetics to solve static and dynamic electromagnetic problems on varying geometries. However, in closely spaced geometries coupled with large aspect ratios, e.g. a large parallel plate capacitor with very small separation gap, the problem exhibits several challenges. Firstly, the close proximity of the field and source elements presents problems with convergence in numerical evaluations of the interactions between them. Secondly, the aspect ratio of the geometry gives an approximation whereby to far field points, the source contributions from locations that are far apart appear to cancel each other. This leads to high condition numbers in the system matrix. This thesis explores the potential solution to these problems as well as the application of modular fast and direct (MFD) [2] solver to expedite the solution of such problems.
Additional file 3 of Analyzing postprandial metabolomics data using multiway models: a simulation study
Creators: name: Li, Lu
name: Yan, Shi
name: Bakker, Barbara M.
name: Hoefsloot, Huub
name: Chawes, Bo
name: Horner, David
name: Rasmussen, Morten A.
name: Smilde, Age K.
name: Acar, Evrim
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 3. Selection of the number of components in CP models.
Residual-Concatenate Neural Network with Deep Regularization Layers for Binary Classification
Creators: name: Gupta, Abhishek
name: Nair, Sruthi
name: Joshi, Raunak
name: Chitre, Vidya
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Many complex Deep Learning models are used with different variations for various prognostication tasks. The higher learning parameters not necessarily ensure great accuracy. This can be solved by considering changes in very deep models with many regularization based techniques. In this paper we train a deep neural network that uses many regularization layers with residual and concatenation process for best fit with Polycystic Ovary Syndrome Diagnosis prognostication. The network was built with improvements from every step of failure to meet the needs of the data and achieves an accuracy of 99.3% seamlessly.
description: 7 pages, 5 figures. To appear in the proceedings of 6th International Conference on Intelligent Computing and Control Systems (ICICCS 2022)
Validity of peripheral oxygen saturation measurements with the Garmin Fēnix® 5X Plus wearable device at 4559 m
Creators: name: Schiefer, Lisa M.
name: Treff, Gunnar
name: Treff, Franziska
name: Schmidt, Peter
name: Schäfer, Larissa
name: Niebauer, Josef
name: Swenson, Kai E.
name: Swenson, Erik R.
name: Berger, Marc M.
name: Sareban, Mahdi
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Accuracy
subject: DDC 610 / Medicine & health
subject: Hypoxia
subject: Altitude
subject: Hypoxie
subject: Höhenanpassung
subject: Höhenkrankheit

description: Decreased oxygen saturation (SO2) at high altitude is associated with potentially life-threatening diseases, e.g., high-altitude pulmonary edema. Wearable devices that allow continuous monitoring of peripheral oxygen saturation (SpO2), such as the Garmin Fēnix® 5X Plus (GAR), might provide early detection to prevent hypoxia-induced diseases. We therefore aimed to validate GAR-derived SpO2 readings at 4559 m. SpO2 was measured with GAR and the medically certified Covidien Nellcor SpO2 monitor (COV) at six time points in 13 healthy lowlanders after a rapid ascent from 1130 m to 4559 m. Arterial blood gas (ABG) analysis served as the criterion measure and was conducted at four of the six time points with the Radiometer ABL 90 Flex. Validity was assessed by intraclass correlation coefficients (ICCs), mean absolute percentage error (MAPE), and Bland–Altman plots. Mean (±SD) SO2, including all time points at 4559 m, was 85.2 ± 6.2% with GAR, 81.0 ± 9.4% with COV, and 75.0 ± 9.5% with ABG. Validity of GAR was low, as indicated by the ICC (0.549), the MAPE (9.77%), the mean SO2 difference (7.0%), and the wide limits of agreement (−6.5; 20.5%) vs. ABG. Validity of COV was good, as indicated by the ICC (0.883), the MAPE (6.15%), and the mean SO2 difference (0.1%) vs. ABG. The GAR device demonstrated poor validity and cannot be recommended for monitoring SpO2 at high altitude.
Additional file 4 of Analyzing postprandial metabolomics data using multiway models: a simulation study
Creators: name: Li, Lu
name: Yan, Shi
name: Bakker, Barbara M.
name: Hoefsloot, Huub
name: Chawes, Bo
name: Horner, David
name: Rasmussen, Morten A.
name: Smilde, Age K.
name: Acar, Evrim
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 4. Comparison of CP models for real vs. simulated data.
sj-docx-1-pus-10.1177_09636625231217081 – Supplemental material for Institutional and non-institutional news trust as predictors of COVID-19 beliefs: Evidence from three European countries
Creators: name: Arrese, Ángel
Publisher: name: SAGE Journals
Year: 2023
Subjects: Communication and Media Studies not elsewhere classified
Science Policy

description: Supplemental material, sj-docx-1-pus-10.1177_09636625231217081 for Institutional and non-institutional news trust as predictors of COVID-19 beliefs: Evidence from three European countries by Ángel Arrese in Public Understanding of Science
Abschlussbericht des Rehabilitationswissenschaftlichen Forschungsverbundes Ulm, Teilprojekt: Determinanten und Ansatzpunkte zur Verbesserung langfristiger Erfolge der stationären kardiologischen Rehabilitation
Creators: name: Brenner, Hermann
name: Rothenbacher, Dietrich
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Bausteine der Reha
subject: KAROLA-Studie
subject: Rehabilitationswissenschaftlicher Forschungsverbund Ulm
subject: DDC 610 / Medicine & health
subject: Coronary disease. Rehabilitation
subject: Rehabilitation
subject: Rehabilitation. Research
subject: Rehabilitationsmedizin

description: Rehabilitation therapy of patients with coronary heart disease (CHD) aims at reducing cardiovascular risk factors and at maintaining reduced risk factor levels. The aim of this analysis was to assess to what degree current in-patient rehabilitation and subsequent out-patient care by general practitioners achieve these goals. As part of the KAROLA-study (long-term success of cardiological rehabilitation therapy) 1206 patients between 30 and 70 years of age (mean age: male 58.3 years, female 60.8 years) who underwent in-patient rehabilitation due to CHD between January 1999 and May 2000 were recruited. Risk factor levels were assessed at the beginning and at the end of in-patient rehabilitation, and patients were re-examined one year after discharge using a standardized exam conducted by the GP. During in-patient rehabilitaion therapy important risk factors of CHD improved on average, but these improvements are only partly sustained in the long term. In in-patient rehabilitation most patients do have to undergo major changes in dietary intake to comply with recommendations. Although some proportion of patients continued to adhere to dietary recommendations in the long run, further research into strategies to improve maintenance of dietary changes is needed to further enhance the long-term benefits from cardiac rehabilitation. Furthermore, we found clear evidence that the impact of smoking abstinence on long term prognosis of patients with coronary heart disease may be considerably larger than suggested by previous studies. Our results underline the importance of efforts to support smoking cessation and to prevent relapse in patients with coronary heart disease. To ensure long-term success of rehabilitation measures more effective maintenance of risk factor modification in subsequent outpatient care is needed.
Supplementary Figure 4:
Creators: name: Piyarungsri, Kakanang
name: Chuammitri, Phongsakorn
name: Pringproa, Kidsadagon
name: Pila, Pattiya
name: Srivorakul, Saralee
name: Sornpet, Benjaporn
name: Pusoonthornthum, Rosama
Publisher: name: SAGE Journals
Year: 2023
Subjects: Veterinary Medicine

description: In periodic acid–Schiff-stained sections, tubular atrophy scoring included grades 1–4.
Additional file 5 of Analyzing postprandial metabolomics data using multiway models: a simulation study
Creators: name: Li, Lu
name: Yan, Shi
name: Bakker, Barbara M.
name: Hoefsloot, Huub
name: Chawes, Bo
name: Horner, David
name: Rasmussen, Morten A.
name: Smilde, Age K.
name: Acar, Evrim
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 5. Experiments on data sets with random noise.
Alternative interpretation of relativistic time-reversal and the time arrow
Creators: name: Zalialiutdinov, T.
name: Solovyev, D.
name: Chubukov, D.
name: Chekhovskoi, S.
name: Labzowsky, L.
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Physics (physics.gen-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: It is well-known that the 4-rotation in the 4-dimensional space-time is equivalent to the CPT-transformation (C is the charge conjugation, P is the space inversion and T is the time-reversal). The standard definition of the T-reversal includes the change of the sign of time variable and replacement of the initial state of the particle (system of particles) by the final state and vice versa. Since the time-reversal operation changes the state of a particle, the particle's wave function cannot be the eigenfunction of the corresponding operator with a certain eigenvalue, as in the case of space parity. Unlike the CPT-transformation, the separate P, T, or C transformations cannot be reduced to any 4-rotation. The extended Lorentz group incorporates all the separate C, P, or T transformations which do not bring the time axis out of the corresponding light cone. The latter restriction is included in the standard definition of the time-reversal. In the present communication, we ignore this restriction. This allows to introduce the "time arrow" operator and characterize every particle by the new quantum number - "time arrow" value. The wave functions of all particles are eigenfunctions of this operator with eigenvalues equal to "time arrow" values. The particles with the "time arrow" values opposite to the "time arrow" value in our universe form another universe (anti-universe). The existence of anti-universe can be confirmed, in principle, by laboratory (atomic) experiments. The anti-universe may be also considered as a candidate to the role of dark matter.
sj-docx-6-tar-10.1177_17534666231218086 – Supplemental material for Effects of external diaphragm pacing combined with conventional rehabilitation therapies in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
Creators: name: Jiang, Linhong
name: Sun, Pingping
name: Li, Peijun
name: Wu, Weibing
name: Wang, Zhenwei
name: Liu, Xiaodan
Publisher: name: SAGE Journals
Year: 2023
Subjects: Aged Health Care
Pharmacology and Pharmaceutical Sciences not elsewhere classified
Respiratory Diseases

description: Supplemental material, sj-docx-6-tar-10.1177_17534666231218086 for Effects of external diaphragm pacing combined with conventional rehabilitation therapies in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis by Linhong Jiang, Pingping Sun, Peijun Li, Weibing Wu, Zhenwei Wang and Xiaodan Liu in Therapeutic Advances in Respiratory Disease
MixedLAB: Mixed Reality to Teach Students Experimental Knowledge in Microfabrication
Creators: name: Brugger, Juergen
Publisher: name: Zenodo
Year: 2024

description: We are developing a new approach to leverage Mixed Reality (MR) affordances for teaching microfabrication processes, such as performed in a cleanroom. Our goal is to design interactive MR content to improve microfabrication and cleanroom training practices. MR presents a promising avenue as it allows hands-free interaction with the system and diminishes cognitive load when learning complex content. We incorporate diverse learning techniques such as real-time feedback, scaffolding, simulations, inquiries, and multimodal interactions to enhance the efficacy and feasibility of educational practices in the design of applications. In a course about microfabrication in bachelor curriculum, we carried out hands-on training sessions in a real cleanroom environment. By the end of the course, five students completed their experiments. We observed that MR was effective in customizing learning experiences and increasing student engagement. Additionally, MR proved helpful for teaching assistants in clarifying complex concepts and phenomena related to the fabrication tools during practical sessions. Although the small sample size limits our ability to draw definitive conclusions, initial qualitative assessments and post-training evaluations suggest that integrating MR into practical engineering education holds great promise.
sj-docx-1-inq-10.1177_00469580231220180 – Supplemental material for Institutional Residence Protects Against Cognitive Frailty: A Cross-Sectional Study
Creators: name: Huang, Jin Hua
name: Wang, Qing Song
name: Zhuo, Rui Min
name: Su, Xin Yu
name: Xu, Qing Yuan
name: Jiang, Yu Hao
name: Li, Yu Han
name: Li, Song Bai
name: Yang, Lan Lan
name: Zang, Rui Wen
name: Meng, Chen Yang
name: Liu, Xue Chun
Publisher: name: SAGE Journals
Year: 2023
Subjects: Nursing not elsewhere classified

description: Supplemental material, sj-docx-1-inq-10.1177_00469580231220180 for Institutional Residence Protects Against Cognitive Frailty: A Cross-Sectional Study by Jin Hua Huang, Qing Song Wang, Rui Min Zhuo, Xin Yu Su, Qing Yuan Xu, Yu Hao Jiang, Yu Han Li, Song Bai Li, Lan Lan Yang, Rui Wen Zang, Chen Yang Meng and Xue Chun Liu in INQUIRY: The Journal of Health Care Organization, Provision, and Financing
Восстановление кислорода на нанокомпозитах медь-ионообменник (КУ-23, LEWATIT K 2620) прикатодной поляризации
Creators: name: Придорогина В. Е.
Publisher: name: Научный корреспондент
Year: 2018

description: Цель работы состояла в исследовании кинетики и динамики процесса электрохимического восстановления кислорода на нанокомпозитах медь-ионообменная матрица (КУ-23; Lewatit K 2620).
Участие республики Армения в интеграционных процессах на постсоветском пространстве в годы президентства С. А. Саргасяна
Creators: name: Шанявский А. И.
Publisher: name: Научный корреспондент
Year: 2018

description: В настоящем исследовании автор изучает интеграционную политику Республики Армения на постсоветском пространстве в 1991-2015 гг. Центральное внимание автор уделяет особенностям периода президентства С. А. Саргсяна, на руководство которого выпал выбор между европейской и евразийской моделями интеграции. В конце исследования автор подводит итоги первого года участия Армении в Евразийском экономическом союзе, после чего в заключении делает общие выводы и формулирует рекомендации. Ключевые слова: Армения, Россия, Евросоюз, СНГ, ОДКБ, ЕврАзЭС, ЕАЭС, Восточное партнерство, комплементаризм, стратегическое партнерство, интеграция.
Additional file 2 of Genome-wide identification, expression profiling, and protein interaction analysis of the CCoAOMT gene family in the tea plant (Camellia sinensis)
Creators: name: Wang, Yiqing
name: Wang, Tao
name: Qi, Siyu
name: Zhao, Jiamin
name: Kong, Jiumei
name: Xue, Zhihui
name: Sun, Weijiang
name: Zeng, Wen
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology
subject: Computational Biology

description: Supplementary Material 2
Human milk fatty acid composition of allergic and non-allergic mothers: the Ulm SPATZ health study
Creators: name: Siziba, Linda P.
name: Lorenz, Leonie
name: Stahl, Bernd
name: Mank, Marko
name: Marosvölgyi, Tamas
name: Decsi, Tamas
name: Rothenbacher, Dietrich
name: Genuneit, Jon
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: maternal allergy
subject: BREAST-MILK
subject: ATOPIC MOTHERS
subject: RISK
subject: DDC 610 / Medicine & health
subject: Milk, Human
subject: Fatty acids
subject: Muttermilch
subject: Allergie
subject: Fettsäuren

description: The aim of this study was to determine the differences in human milk fatty acid composition in relation to maternal allergy within a large birth cohort study using statistical methods accounting for the correlations that exist in compositional data. We observed marginal differences in human milk fatty acid composition of allergic and non-allergic mothers. However, our results do not support the hypothesis that human milk fatty acid composition is influenced by allergy or that it differs between mothers with or without allergy. Observed differences in our results between transformed and untransformed fatty acid data call for re-evaluation of previous, as well as future, studies using statistical methods appropriate for compositionality of fatty acid data.
An integrated population model to project viability of a northern bobwhite population in Ohio [DATA]
Creators: name: Rosenblatt, Connor
Publisher: name: Zenodo
Year: 2021

description: Increased variation in interannual weather due to climate change can exert a powerful influence on the population dynamics of a species. Understanding the influence of severe weather is important for managing weather-sensitive species. While best management practices target vital rates that are affected by weather, focusing on a single vital rate may not be sufficient if other vital rates are secondarily limiting. A comprehensive modeling framework to forecast future population dynamics while incorporating weather scenarios and vital rate variation within observed ranges that can be affected by management actions are necessary. A potential approach is to combine an integrated population model (IPM) with a population viability analysis (PVA) to generate novel insights about population dynamics. We used the northern bobwhite (Colinus virginianus), a rapidly declining gamebird sensitive to snowfall along the northern extents of the species' range, to demonstrate the utility of a coupled IPM-PVA framework for projecting the response of a population to weather, management, and changes in vital rates. We created an IPM using two sources of count data spanning seven years, five years of winter survival data, and two years of breeding season demographics for a declining bobwhite population in southwestern Ohio during 2007–2015. Quasi-extinction probability at the end of the decadal projection during 2019–2029 was 0.384–0.410 for mild, average, and severe winter weather scenarios. Quasi-extinction probability declined to 0.326 with 20% improvement in nest success and summer survival rates. A concurrent 20% increase in winter survival further reduced quasi-extinction probability to 0.263, which is a ~36% reduction in quasi-extinction probability compared to the baseline scenario with no changes in vital rates. These results suggest that long-term viability of this population may depend on extensive management of winter habitat to improve survival but will also require management actions to improve fecundity after severe winters. Our modeling approach demonstrated how IPMs can be used to project population responses to future weather conditions and overcome some of the pitfalls of traditional PVA. The coupled framework presented here can serve as a tool for managers to make climate informed management decisions.
description: Questions regarding dataset can be directed to: Connor Rosenblatt UC Davis, Department of Environmental Science and Policy connor.rosenblatt16@gmail.com
title: Курс физики с примерами из интернет-экзамена (Механика. Молекулярная физика и термодинамика)
title: Учебное пособие
titleType: Subtitle
Creators: name: Соппа М.С.
Publisher: name: Новосибирский государственный архитектурно-строительный университет (Сибстрин)
Year: 2015

description: В данном учебном пособии рассмотрены основные понятия и законы курса физики (разделы «Механика», «Молекулярная физика и термодинамика»). Изучение тем ориентировано на самостоятельную работу. Приведены наборы типовых тестов и задач, которые используются при проведении федерального интернет-тестирования. Учебное пособие предназначено для студентов, обучающихся по направлению подготовки 08.03.01 «Строительство».
description: This tutorial describes the basic concepts and laws of physics courses (sections "Mechanics", "Molecular physics and thermodynamics"). The study is focused on independent work. Given a series of standard tests and tasks used in the Federal Internet testing. The manual is intended for students enrolled by specialty 08.03.01 "Construction".
Syntax-Guided Program Reduction for Understanding Neural Code Intelligence Models
Creators: name: Rabin, Md Rafiqul Islam
name: Hussain, Aftab
name: Alipour, Mohammad Amin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Software Engineering (cs.SE)
subject: Machine Learning (cs.LG)
subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: Neural code intelligence (CI) models are opaque black-boxes and offer little insight on the features they use in making predictions. This opacity may lead to distrust in their prediction and hamper their wider adoption in safety-critical applications. Recently, input program reduction techniques have been proposed to identify key features in the input programs to improve the transparency of CI models. However, this approach is syntax-unaware and does not consider the grammar of the programming language. In this paper, we apply a syntax-guided program reduction technique that considers the grammar of the input programs during reduction. Our experiments on multiple models across different types of input programs show that the syntax-guided program reduction technique is faster and provides smaller sets of key tokens in reduced programs. We also show that the key tokens could be used in generating adversarial examples for up to 65% of the input programs.
description: The 6th ACM SIGPLAN International Symposium on Machine Programming (MAPS'22); Related to arXiv:2202.06474
A prospective feasibility trial to challenge patient−derived pancreatic cancer organoids in predicting treatment response
Creators: name: Beutel, Alica K.
name: Schütte, Lena
name: Scheible, Jeanette
name: Roger, Elodie
name: Müller, Martin
name: Perkhofer, Lukas
name: Kestler, Annika M. T. U.
name: Kraus, Johann M.
name: Kestler, Hans A.
name: Barth, Thomas F. E.
name: Lemke, Johannes
name: Kornmann, Marko
name: Ettrich, Thomas J.
name: Gout, Johann
name: Seufferlein, Thomas
name: Kleger, Alexander
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: pancreatic cancer
subject: organoids
subject: drug response prediction
subject: pharmacotyping
subject: personalized medicine
subject: DDC 610 / Medicine & health
subject: Pancreatic neoplasms
subject: Precision medicine
subject: Drug delivery systems
subject: Pharmacogenetics
subject: Organoids
subject: Bauchspeicheldrüsenkrebs
subject: Arzneimittelentwicklung
subject: Individualisierte Medizin
subject: Organoid

description: Real-time isolation, propagation, and pharmacotyping of patient-derived pancreatic cancer organoids (PDOs) may enable treatment response prediction and personalization of pancreatic cancer (PC) therapy. In our methodology, PDOs are isolated from 54 patients with suspected or confirmed PC in the framework of a prospective feasibility trial. The drug response of single agents is determined by a viability assay. Areas under the curves (AUC) are clustered for each drug, and a prediction score is developed for combined regimens. Pharmacotyping profiles are obtained from 28 PDOs (efficacy 63.6%) after a median of 53 days (range 21–126 days). PDOs exhibit heterogeneous responses to the standard-of-care drugs, and are classified into high, intermediate, or low responder categories. Our developed prediction model allows a successful response prediction in treatment-naïve patients with an accuracy of 91.1% for first-line and 80.0% for second-line regimens, respectively. The power of prediction declines in pretreated patients (accuracy 40.0%), particularly with more than one prior line of chemotherapy. Progression-free survival (PFS) is significantly longer in previously treatment-naïve patients receiving a predicted tumor sensitive compared to a predicted tumor resistant regimen (mPFS 141 vs. 46 days; p = 0.0048). In conclusion, generation and pharmacotyping of PDOs is feasible in clinical routine and may provide substantial benefit.
Additional file 1 of Impact of preoperative antiviral therapy on the prognosis of hepatitis B virus-related hepatocellular carcinoma
Creators: name: Liang, Yuxin
name: Zhong, Deyuan
name: Zhang, Zilong
name: Su, Yuhao
name: Yan, Su
name: Lai, Chunyou
name: Yao, Yutong
name: Shi, Ying
name: Huang, Xiaolun
name: Shang, Jin
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplementary Material 1
title: Anwendungen der Differential- und Integralrechnung in der Mathematik, der Physik und in anderen Gebieten (Gymnasium und HTL)
Creators: name: Langer, Sabrina
Year: 2009

description: Diese Diplomarbeit behandelt die Anwendung der Differential und Integralrechnung im Schulunterricht. In beiden Teilen wird zuerst der Lehrplanbezug hergestellt und nach einer kurzen Erläuterung der Theorieinhalte auf die Beispiele eingegangen. Im ersten Teil werden Anwendungen der Differentialrechnung in den Bereichen Differenzen und Differentialquotient, Kurvendiskussion und Extremwertaufgaben vorgestellt. Im zweiten Teil werden Anwendungen der Integralrechnung in den Bereichen Mittelwert, Volumen und Weglänge vorgestellt.
The semantic content of abstract concepts: a property listing study of 296 abstract words
Creators: name: Harpaintner, Marcel
name: Trumpp, Natalie Maria
name: Kiefer, Markus
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: abstract concepts
subject: grounded cognition
subject: conceptual representation
subject: embodied cognition
subject: language comprehension
subject: DDC 150 / Psychology
subject: Semantic memory
subject: Hierarchical cluster analysis
subject: Embodiment
subject: Sprachverstehen

description: The relation of abstract concepts to the modality-specific systems is discussed controversially. According to classical approaches, the semantic content of abstract concepts can only be coded by amodal or verbal-symbolic representations distinct from the sensory and motor systems, because abstract concepts lack a clear physical referent. Grounded cognition theories, in contrast, propose that abstract concepts do not depend only on the verbal system, but also on a variety of modal systems involving perception, action, emotion and internal states. In order to contribute to this debate, we investigated the semantic content of abstract concepts using a property generation task. Participants were asked to generate properties for 296 abstract concepts, which are relevant for constituting their meaning. These properties were categorized by a coding-scheme making a classification into modality-specific and verbal contents possible. Words were additionally rated with regard to concreteness/abstractness and familiarity. To identify possible subgroups of abstract concepts with distinct profiles of generated features, hierarchical cluster analyses were conducted. Participants generated a substantial proportion of introspective, affective, social, sensory and motor-related properties, in addition to verbal associations. Cluster analyses revealed different subcategories of abstract concepts, which can be characterized by the dominance of certain conceptual features. The present results are therefore compatible with grounded cognition theories, which emphasize the importance of linguistic, social, introspective and affective experiential information for the representation of abstract concepts. Our findings also indicate that abstract concepts are highly heterogeneous requiring the investigation of well-specified subcategories of abstract concepts, for instance as revealed by the present cluster analyses. The present study could thus guide future behavioral or imaging work further elucidating the representation of abstract concepts.
Договор участия в долевом строительстве объектов недвижимости
Creators: name: Манилов И. О.
Publisher: name: Научный корреспондент
Year: 2018

description: Объектом исследования являются правоотношения, возникающие в сфере долевого строительства объектов недвижимости. Цель работы - изучение договора участия в долевом строительстве, включая: анализ проблем, возникающих при исполнении данного договора; и предложения возможных путей выхода из этих проблем. В работе дана характеристика понятию «договор участия в долевом строительстве»; выявлены особенности требований к сторонам договора; раскрыты существенные условия договора; проведен сравнительный анализ договора со смежными правоотношениями; рассмотрены особенности заключения и расторжения договора; изучены основные новеллы в законодательстве о долевом строительстве; проведен анализ проблем, возникающих при исполнении данного договора; предложены возможные пути выхода из данных проблем.
Конфликтологические и правовые аспекты домашнего насилия
Creators: name: Говоруха А. М.
Publisher: name: Научный корреспондент
Year: 2018

description: Практическая значимость исследования заключается в том, что материалы и выводы, представленные в исследовании, могут быть использованы для анализа роли домашнего насилия в актуализации семейных конфликтов, для выработки стратегий регулирования и предотвращения подобных конфликтов в современном обществе. Актуализируют проблему семейного насилия поликонфессиональность и многонациональность российского общества.
Observation of Supersymmetry and its Spontaneous Breaking in a Trapped Ion Quantum Simulator
Creators: name: Cai, M. -L.
name: Wu, Y. -K.
name: Mei, Q. -X.
name: Zhao, W. -D.
name: Jiang, Y.
name: Yao, L.
name: He, L.
name: Zhou, Z. -C.
name: Duan, L. -M.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Supersymmetry (SUSY) helps solve the hierarchy problem in high-energy physics and provides a natural groundwork for unifying gravity with other fundamental interactions. While being one of the most promising frameworks for theories beyond the Standard Model, its direct experimental evidence in nature still remains to be discovered. Here we report experimental realization of a supersymmetric quantum mechanics (SUSY QM) model, a reduction of the SUSY quantum field theory for studying its fundamental properties, using a trapped ion quantum simulator. We demonstrate the energy degeneracy caused by SUSY in this model and the spontaneous SUSY breaking. By a partial quantum state tomography of the spin-phonon coupled system, we explicitly measure the supercharge of the degenerate ground states, which are superpositions of the bosonic and the fermionic states. Our work demonstrates the trapped-ion quantum simulator as an economic yet powerful platform to study versatile physics in a single well-controlled system.
description: 8 pages, 4 figures
sj-pdf-1-jis-10.1177_01655515221125321 – Supplemental material for The cross-subsidy and buy-one-give-one models of compensated peer review: A comparative study for mission-driven journals
Creators: name: García, Jose A
name: Rodriguez-Sánchez, Rosa María
name: Fdez-Valdivia, J
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: Supplemental material, sj-pdf-1-jis-10.1177_01655515221125321 for The cross-subsidy and buy-one-give-one models of compensated peer review: A comparative study for mission-driven journals by Jose A García, Rosa María Rodriguez-Sánchez and J Fdez-Valdivia in Journal of Information Science
Исследование эффекта переключения в тонких пленках материала фазовой памяти Ge2Sb2Te5
Creators: name:  Глухенькая В. Б.
Publisher: name: Научный корреспондент
Year: 2018

description: В ходе проведения исследовательской работы был разработан аппаратно-технический комплекс, позволяющий исследовать эффект переключения с памятью в режиме постоянного и импульсного напряжения. По результатам измерений было установлено, что величина порогового напряжения переключения не превышает 1 В, длительность перехода материала Ge2Sb2Te5 из высокоомного в низкоомное состояние составляет ~ 20 нс, а время переключения варьируется от 180 до 240 нс. Полученные результаты носят прикладной характер и могут быть использованы для повышения энергоэффективности РСМ-устройств.
Between a rock and a hard polytomy: phylogenomics of the rock-dwelling mbuna cichlids of Lake Malawi
Creators: name: Scherz, Mark D.
name: Masonick, Paul
name: Meyer, Axel
name: Hulsey, C. Darrin
Publisher: name: Zenodo
Year: 2022
Subjects: Cichlidae
multi-species coalescent
linkage disequilibrium (LD)
rapid radiation
soft polytomy
introgression

description: Whole genome sequences are beginning to revolutionise our understanding of phylogenetic relationships. Yet, even whole genome sequences can fail to resolve the evolutionary history of the most rapidly radiating lineages, where incomplete lineage sorting, standing genetic variation, introgression, and other factors obscure the phylogenetic history of the group. To overcome such challenges, one emerging strategy is to integrate results across different methods. Most such approaches have been implemented on reduced representation genomic datasets, but whole genomes should provide the maximum possible evidence approach. Here, we test the ability of SNPs extracted from whole genome resequencing data, implemented in an integrative genomic approach, to resolve key nodes in the phylogeny of the mbuna, rock-dwelling cichlid fishes of Lake Malaŵi, which epitomise the phylogenetic intractability that often accompanies explosive lineage diversification. This monophyletic radiation has diversified at an unparalleled rate into several hundred species in less than two million years. Using an array of phylogenomic methods, we consistently recovered four major clades of mbuna, but a large basal polytomy among them. Although introgression between clades apparently contributed to the challenge of phylogenetic reconstruction, reduction of the dataset to non-introgressed sites still did not help to resolve the basal polytomy. On the other hand, relationships among six congeneric species pairs were resolved without ambiguity, even in one case where existing data led us to predict that resolution would be difficult. We conclude that the bursts of diversification at the earliest stages of the mbuna radiation may be phylogenetically unresolvable, but other regions of the tree are phylogenetically clearly supported. Integration of multiple phylogenomic approaches will continue to increase confidence in relationships inferred from these and other whole-genome datasets.
description: Funding provided by: Deutsche Forschungsgemeinschaft
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100001659
Award Number: ME 1725/21-1
Additional file 2 of Impact of preoperative antiviral therapy on the prognosis of hepatitis B virus-related hepatocellular carcinoma
Creators: name: Liang, Yuxin
name: Zhong, Deyuan
name: Zhang, Zilong
name: Su, Yuhao
name: Yan, Su
name: Lai, Chunyou
name: Yao, Yutong
name: Shi, Ying
name: Huang, Xiaolun
name: Shang, Jin
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplementary Material 2
title: Лабораторный практикум по современным компьютерным технологиям. Часть 1. Word
title: Учебное пособие
titleType: Subtitle
Creators: name: Ершова Е.Е.
Publisher: name: Новосибирский государственный архитектурно-строительный университет (Сибстрин)
Year: 2007

description: Учебное пособие написано в соответствии с программой курсов «Информатика» и «Информационные технологии», содержит лабораторные работы, охватывающие основные возможности редактора Word, используемые при создании различных документов: писем, поздравлений, отчетов, курсовых и дипломных работ, докладов, электронных документов и учебников, электронных тестов и т.д. Каждая лабораторная работа снабжена подробными рекомендациями для ее успешного выполнения. Учебное пособие предназначено для студентов специальности 040201 «Социология», будет полезно для студентов других специальностей и преподавателей в качестве практического руководства в изучении редактора Word.
description: The manual is written in accordance with the program of the course "Informatics" and "Information technology" includes laboratory work, covering the main features of the Word editor used in the creation of various documents: letters, greetings, reports, term papers and dissertations, reports, electronic documents and text books, electronic tests, etc. Each lab is provided with detailed recommendations for its successful implementation. The textbook is designed for students majoring 040201 Sociology will be useful for students of other majors and teachers as a practical guide to the study of the Word editor.
Deletion of NEMO inhibits EMT and reduces metastasis in KPC mice
Creators: name: Tsesmelis, Miltiadis
name: Tiwary, Kanishka
name: Steiger, Katja
name: Sperb, Nadine
name: Gerstenlauer, Melanie
name: Manfras, Uta
name: Maier, Harald J.
name: Hermann, Patrick C.
name: Chan, Lap Kwan
name: Wirth, Thomas
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: PDAC
subject: pancreatic cancer
subject: NEMO
subject: NF-κB
subject: KPC
subject: EMT
subject: DDC 610 / Medicine & health
subject: Pancreas; Cancer
subject: Pancreatic neoplasms
subject: Neoplasm metastasis
subject: NF-kappa B
subject: Signal transduction
subject: Bauchspeicheldrüsenkrebs
subject: Metastase
subject: Nuklearfaktor Kappa B

description: Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is highly metastatic and is expected to be the second leading cause of cancer-related deaths in the USA by 2030. In the current study, we investigated the role of NEMO/NF-κB signaling in the development and metastasis of PDAC by using the genetically modified KPC mouse model. In the absence of NEMO, KPC mice exhibited extended survival, which was accompanied by a strong reduction in the development of liver metastasis and ascites. Our study provides evidence for a detrimental role of the conventional NF-κB pathway in the survival of KPC mice and underlines the fact that NF-κB could be a therapeutic target against PDAC. Abstract Pancreatic ductal adenocarcinoma (PDAC) remains a largely incurable cancer type. Its high mortality is attributed to the lack of efficient biomarkers for early detection combined with its high metastatic properties. The aim of our study was to investigate the role of NF-κB signaling in the development and metastasis of PDAC. We used the well-established KPC mouse model, and, through genetic manipulation, we deleted NF-κB essential modulator (NEMO) in the pancreata of KPC mice. Interestingly, NEMO deletion altered the differentiation status of the primary tumor but did not significantly affect its development. However, in the absence of NEMO, the median survival of the mice was prolonged by 13.5 days (16%). In addition, examination of the liver demonstrated that, whereas KPC mice occasionally developed liver macro-metastasis, NEMO deletion completely abrogated this outcome. Further analysis of the tumor revealed that the expression of epithelial–mesenchymal transition (EMT) transcription factors was diminished in the absence of NEMO. Conclusively, our study provides evidence that NF-κB is dispensable for the progression of high-grade PanINs towards PDAC. In contrast, NF-κB signaling is essential for the development of metastasis by regulating the gene expression program of EMT.
title: Лекции по аналитической механике
title: Учебное пособие
titleType: Subtitle
Creators: name: Юдин В.А.
Publisher: name: Новосибирский государственный архитектурно-строительный университет (Сибстрин)
Year: 2016

description: Учебное пособие включает три лекции по аналитической механике, посвященных рассмотрению принципа Даламбера, принципа возможных перемещений и принципа Даламбера-Лагранжа. Пособие предназначено для студентов, обучающихся по направлению подготовки 08.03.01 «Строительство» и специальности 08.05.01 «Строительство уникальных зданий и сооружений» всех форм обучения.
description: The tutorial includes three lectures on analytical mechanics is devoted to the consideration of the principle of d'alembert, principle of possible displacements and the principle of d'alembert-Lagrange. The textbook is intended for students enrolled by specialty 08.03.01 "Construction" and specialty 08.05.01 "Construction of unique buildings and structures" all forms of education.
title: Лекции по динамике точки
title: Учебное пособие
titleType: Subtitle
Creators: name: Юдин В.А.
Publisher: name: Новосибирский государственный архитектурно-строительный университет (Сибстрин)
Year: 2014

description: Учебное пособие включает пять лекций по динамике точки: динамика материальной точки, прямолинейные колебания точки, несвободное движение точки, движение точки в неинерциальной системе отсчета, общие теоремы динамики точки. А также содержит приложение с изложением методов интегрирования встречающихся в лекциях дифференциальных уравнений. Пособие предназначено для студентов всех специальностей дневной и вечерней форм обучения.
description: The manual includes five lectures on the dynamics of point: dynamics of a particle rectilinear vibration of the point, proprietary movement points, movement points in non-inertial reference frame, General theorems of dynamics of a point. And also contains an Annex describing the methods of integration used in the lectures of the differential equations. The textbook is intended for students of all specialties of day and evening classes.
title: Лекции по общим теоремам динамики механических систем
title: Учебное пособие
titleType: Subtitle
Creators: name: Юдин В.А.
Publisher: name: Новосибирский государственный архитектурно-строительный университет (Сибстрин)
Year: 2015

description: Учебное пособие включает четыре лекции по динамике механических систем: введение в динамику механической системы, теоремы о движении центра масс и об изменении количества движения, теорему об изменении момента количества движения, теорему об изменении кинетической энергии. Пособие предназначено для студентов всех специальностей дневной и вечерней форм обучения.
description: The manual includes four lectures on dynamics of mechanical systems: an introduction to the dynamics of the mechanical system, the theorem of motion of center of mass and the change of momentum, the theorem of change of moment of momentum, the theorem on change of kinetic energy. The textbook is intended for students of all specialties of day and evening classes.