cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Appendix from Greater wealth inequality, less polygyny: rethinking the polygyny threshold model.
Creators: name: Ross, Cody T.
name: Mulder, Monique Borgerhoff
name: Seung-Yun Oh
name: Bowles, Samuel
name: Beheim, Bret
name: Bunce, John
name: Caudell, Mark
name: Clark, Gregory
name: Colleran, Heidi
name: Cortez, Carmen
name: Draper, Patricia
name: Greaves, Russell D.
name: Gurven, Michael
name: Headland, Thomas
name: Headland, Janet
name: Hill, Kim
name: Hewlett, Barry
name: Kaplan, Hillard S.
name: Koster, Jeremy
name: Kramer, Karen
name: Marlowe, Frank
name: McElreath, Richard
name: Nolin, David
name: Quinlan, Marsha
name: Quinlan, Robert
name: Caissa Revilla-Minaya
name: Scelza, Brooke
name: Schacht, Ryan
name: Shenk, Mary
name: Uehara, Ray
name: Voland, Eckart
name: Willführ, Kai
name: Winterhalder, Bruce
name: Ziker, John
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: Monogamy appears to have become the predominant human mating system with the emergence of highly unequal agricultural populations that replaced relatively egalitarian horticultural populations, challenging the conventional idea—based on the polygyny threshold model—that polygyny should be positively associated with wealth inequality. To address this polygyny paradox, we generalize the standard polygyny threshold model to a mutual mate choice model predicting the fraction of women married polygynously. We then demonstrate two conditions that are jointly sufficient to make monogamy the predominant marriage form, even in highly unequal societies. We assess if these conditions are satisfied using individual-level data from 29 human populations. Our analysis shows that with the shift to stratified agricultural economies: (i) the population frequency of relatively poor individuals increased, increasing wealth inequality, but decreasing the frequency of individuals with sufficient wealth to secure polygynous marriage, and (ii) diminishing marginal fitness returns to additional wives prevent extremely wealthy men from obtaining as many wives as their relative wealth would otherwise predict. These conditions jointly lead to a high population-level frequency of monogamy.
Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells
Creators: name: Tang, Jie
name: Mahler, Stephen M.
name: Xu, Zhi Ping
name: Li, Li
name: Huang, Leaf
name: Howard, Christopher B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The optimized lipid coated calcium phosphate nanoparticles more efficiently deliver functional siRNA and inhibit the cancer cell growth, in comparison with the commercial transfection agent Oligofactamine TM .
Energy Efficient Sampling Policies for Edge Computing Feedback Systems
Creators: name: Moothedath, Vishnu Narayanan
name: Champati, Jaya Prakash
name: Gross, James
Publisher: name: arXiv
Year: 2021
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: We study the problem of finding efficient sampling policies in an edge-based feedback system, where sensor samples are offloaded to a back-end server that processes them and generates feedback to a user. Sampling the system at maximum frequency results in the detection of events of interest with minimum delay but incurs higher energy costs due to the communication and processing of redundant samples. On the other hand, lower sampling frequency results in higher delay in detecting the event, thus increasing the idle energy usage and degrading the quality of experience. We quantify this trade-off as a weighted function between the number of samples and the sampling interval. We solve the minimisation problem for exponential and Rayleigh distributions, for the random time to the event of interest. We prove the convexity of the objective functions by using novel techniques, which can be of independent interest elsewhere. We argue that adding an initial offset to the periodic sampling can further reduce the energy consumption and jointly compute the optimum offset and sampling interval. We apply our framework to two practically relevant applications and show energy savings of up to 36% when compared to an existing periodic scheme.
Tri-peptide cationic lipids for gene delivery
Creators: name: Cui, Shaohui
name: Zhang, Yuan
name: Zhang, Shufen
name: Zhang, Shubiao
name: Zhi, Defu
name: Huang, Leaf
name: Zhao, Yinan
name: Chen, Huiying
name: Zhen, Yuhong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: A novel tri-peptide cationic lipid can efficiently transfer DNA and siRNA into tumor cells and tumors of mice with little in vitro and in vivo toxicity.
Influence of false-positive mammography results on subsequent screening: do physician recommendations buffer negative effects?
Creators: name: DeFrank, Jessica T
name: Earp, Jo Anne
name: Brewer, Noel T
name: Rimer, Barbara K
name: Breslau, Erica S
name: Bowling, J Michael
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Cancer screening guidelines often include discussion about the unintended negative consequences of routine screening. This prospective study examined effects of false-positive mammography results on women’s adherence to subsequent breast cancer screening and psychological well-being. We also assessed whether barriers to screening exacerbated the effects of false-positive results.
Interplay of Magnetic Order, Pairing and Phase Separation in a One Dimensional Spin Fermion Model
Creators: name: Hu, Wenjian
name: Scalettar, Richard T.
name: Singh, Rajiv R. P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We consider a lattice model of itinerant electrons coupled to an array of localized classical Heisenberg spins. The nature of the ground state ordered magnetic phases that result from the indirect spin-spin coupling mediated by the electrons is determined as a function of density and the spin-fermion coupling $J$. At a fixed chemical potential, spiral phases exist only up to values of $J$ which are less than roughly half the electronic bandwidth. At a fixed electron density and near half filling, the system phase separates into a half-filled antiferromagnetic phase and a spiral phase. The ferromagnetic phases are shown to be fully polarized, while the spiral phases have equal admixture of up and down spins. Phase separation survives in the presence of weak pairing field $Δ$ but disappears when $Δ$ exceeds a critical value $Δ_c$. If pairing fields are large enough, an additional spiral state arises at strong coupling $J$. The relevance of this study, especially the phase separation, to artificially engineered systems of adjacent itinerant electrons and localized spins is discussed. In particular, we propose a method which might allow for the braiding of Majorana fermions by changing the density and moving their location as they are pulled along by a phase separation boundary.
description: 7 pages, 10 figures
Zero Magnetic Field Plateau Phase Transition in Higher Chern Number Quantum Anomalous Hall Insulators
Creators: name: Zhao, Yi-Fan
name: Zhang, Ruoxi
name: Zhou, Ling-Jie
name: Mei, Ruobing
name: Yan, Zi-Jie
name: Chan, Moses H. W.
name: Liu, Chao-Xing
name: Chang, Cui-Zu
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The plateau-to-plateau transition in quantum Hall effect under high magnetic fields is a celebrated quantum phase transition between two topological states through either sweeping the magnetic field or tuning the carrier density. The recent realization of the quantum anomalous Hall (QAH) insulators with tunable Chern numbers introduces the channel degree of freedom to the dissipation-free chiral edge transport and makes the study of the quantum phase transition between two topological states under zero magnetic field possible. Here, we synthesized the magnetic topological insulator (TI)/TI penta-layer heterostructures with different Cr doping concentrations in the middle magnetic TI layers using molecular beam epitaxy (MBE). By performing transport measurements, we found a zero magnetic field quantum phase transition between the C = 1 and C = 2 QAH states. In tuning the transition, the Hall resistance monotonically decreases from h/e2 to h/2e2, concurrently, the longitudinal resistance exhibits a maximum at the critical point. Our results show that the ratio between the Hall resistance and the longitudinal resistance is greater than 1 at the critical point, which indicates that the original chiral edge channel from the C = 1 QAH state coexists with the dissipative bulk conduction channels. Subsequently, these bulk conduction channels appear to self-organize and form the second chiral edge channel in completing the plateau phase transition. Our study will motivate further investigations of this novel Chern number change-induced quantum phase transition and advance the development of the QAH chiral edge current-based electronic and spintronic devices.
description: 19 pages, 4 figures, Comments are welcome
Appendix from Greater wealth inequality, less polygyny: rethinking the polygyny threshold model
Creators: name: Ross, Cody T.
name: Mulder, Monique Borgerhoff
name: Seung-Yun Oh
name: Bowles, Samuel
name: Beheim, Bret
name: Bunce, John
name: Caudell, Mark
name: Clark, Gregory
name: Colleran, Heidi
name: Cortez, Carmen
name: Draper, Patricia
name: Greaves, Russell D.
name: Gurven, Michael
name: Headland, Thomas
name: Headland, Janet
name: Hill, Kim
name: Hewlett, Barry
name: Kaplan, Hillard S.
name: Koster, Jeremy
name: Kramer, Karen
name: Marlowe, Frank
name: McElreath, Richard
name: Nolin, David
name: Quinlan, Marsha
name: Quinlan, Robert
name: Caissa Revilla-Minaya
name: Scelza, Brooke
name: Schacht, Ryan
name: Shenk, Mary
name: Uehara, Ray
name: Voland, Eckart
name: Willführ, Kai
name: Winterhalder, Bruce
name: Ziker, John
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: Monogamy appears to have become the predominant human mating system with the emergence of highly unequal agricultural populations that replaced relatively egalitarian horticultural populations, challenging the conventional idea—based on the polygyny threshold model—that polygyny should be positively associated with wealth inequality. To address this polygyny paradox, we generalize the standard polygyny threshold model to a mutual mate choice model predicting the fraction of women married polygynously. We then demonstrate two conditions that are jointly sufficient to make monogamy the predominant marriage form, even in highly unequal societies. We assess if these conditions are satisfied using individual-level data from 29 human populations. Our analysis shows that with the shift to stratified agricultural economies: (i) the population-frequency of relatively poor individuals increased, increasing wealth inequality, but decreasing the frequency of individuals with sufficient wealth to secure polygynous marriage, and (ii) diminishing marginal fitness returns to additional wives prevent extremely wealthy men from obtaining as many wives as their relative wealth would otherwise predict. These conditions jointly lead to a high population-level frequency of monogamy.
Interferon stimulated exonuclease gene 20 kDa links psychiatric events to distinct hepatitis C virus responses in human immunodeficiency virus positive patients: ISG20 Links Psychiatric Events to HCV Clearance
Creators: name: Lempicki, Richard A.
name: Kottilil, Shyam
name: Rosenstein, Donald L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Hepatitis C Virus (HCV) infection occurs frequently in patients with preexisting mental illness. Treatment for chronic hepatitis C using interferon formulations often increases risk for neuropsychiatric symptoms. Pegylated-Interferon-α (PegIFN-α) remains crucial for attaining sustained virologic response (SVR); however, PegIFN-α based treatment is associated with psychiatric adverse effects, which require dose reduction and/or interruption. This study's main objective was to identify genes induced by PegIFN-α and expressed in the central nervous system and immune system, which could mediate the development of psychiatric toxicity in association with antiviral outcome. Using peripheral blood mononuclear cells from Human Immunodeficiency Virus (HIV)/HCV co-infected donors (N=28), DNA microarray analysis was performed and 21 differentially regulated genes were identified in patients with psychiatric toxicity vs. those without. Using these 21 expression profiles a two-way-ANOVA was performed to select genes based on antiviral outcome and occurrence of neuropsychiatric adverse events. Microarray analysis demonstrated that Interferon-stimulated-exonuclease-gene 20kDa (ISG20) and Interferon-alpha-inducible-protein 27 (IFI27) were the most regulated genes (P<0.05) between three groups that were built by combining antiviral outcome and neuropsychiatric toxicity. Validation by bDNA assay confirmed that ISG20 expression levels were significantly associated with these outcomes (P<0.035). Baseline levels and induction of ISG20 correlated independently with no occurrence of psychiatric adverse events and non-response to therapy (P<0.001). Among the 21 genes that were associated with psychiatric adverse events and 20 Interferon-inducible genes (IFIGs) used as controls, only ISG20 expression was able to link PegIFN-α related neuropsychiatric toxicity to distinct HCV-responses in patients co-infected with HIV and HCV in vivo.
Gralsburg und Ehrenmal
Creators: name: Mogge, Winfried
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 55 Nr. 2 (2014): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
On Newton's Rule of Signs
Creators: name: Prodanov, Emil M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Mathematics (math.GM)
subject: FOS: Mathematics
subject: 12D10, 26C10, 26D05

description: Analysing the cubic sectors of a real polynomial of degree n, a modification of the Newton Rule is Signs is proposed with which stricter upper bound on the number of real roots can be found. A new necessary condition for reality of the roots of a polynomial is also proposed. Relationship among the quadratic elements of the polynomial is established through its roots and those of its derivatives. Some aspects of polynomial discriminants are also discussed - the relationship between the discriminants of real polynomials, the discriminants of their derivatives, and the quadratic elements - following a discriminant of the discriminant approach.
description: 32 pages, 4 figures. Extended discussion
Construction of a Rapoport-Zink space for $\mathrm{GU}(1,1)$ in the ramified $2$-adic case
Creators: name: Kirch, Daniel
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 11G18, 14G35

description: Let $F|\mathbb{Q}_2$ be a finite extension. In this paper, we construct an RZ-space $\mathcal{N}_E$ for split $\mathrm{GU}(1,1)$ over a ramified quadratic extension $E|F$. For this, we first introduce the naive moduli problem $\mathcal{N}_E^{\mathrm{naive}}$ and then define $\mathcal{N}_E \subseteq \mathcal{N}_E^{\mathrm{naive}}$ as a canonical closed formal subscheme, using the so-called straightening condition. We establish an isomorphism between $\mathcal{N}_E$ and the Drinfeld moduli problem, proving the $2$-adic analogue of a theorem of Kudla and Rapoport. The formulation of the straightening condition uses the existence of certain polarizations on the points of the moduli space $\mathcal{N}_E^{\mathrm{naive}}$. We show the existence of these polarizations in a more general setting over any quadratic extension $E|F$, where $F|\mathbb{Q}_p$ is a finite extension for any prime $p$.
description: 37 pages
Datasets methods, general methods and supplemental results from The repeatability of cognitive performance: a meta-analysis.
Creators: name: M. Cauchoix
name: P. K. Y. Chow
name: J. O. Van Horik
name: C.M. Atance
name: EJ Barbeau
name: G. Barragan-Jason
name: P. Bize
name: A. Boussard
name: S. D. Buechel
name: A. Cabirol
name: L. Cauchard
name: N. Claidière
name: S. Dalesman
name: J. M. Devaud
name: M. Didic
name: B. Doligez
name: J. Fagot
name: C. Fichtel
name: J. Henke-Von Der Malsburg
name: E. Hermer
name: L. Huber
name: F. Huebner
name: P. M. Kappeler
name: S. Klein
name: J. Langbein
name: E. J. G. Langley
name: S. E. G. Lea
name: M. Lihoreau
name: H. Lovlie
name: L. D. Matzel
name: S. Nakagawa
name: C. Nawroth
name: S. Oesterwind
name: B. Sauce
name: E. Smith
name: E. Sorato
name: S. Tebbich
name: L. J. Wallis
name: M. A. Whiteside
name: A. Wilkinson
name: A. S. Chaine
name: J. Morand-Ferron
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour

description: Behavioural and cognitive processes play important roles in mediating an individual's interactions with its environment. Yet, while there is a vast literature on repeatable individual differences in behaviour, relatively little is known about the repeatability of cognitive performance. To further our understanding of the evolution of cognition, we gathered 44 studies on individual performance of 25 species across six animal classes and used meta-analysis to assess whether cognitive performance is repeatable. We compared repeatability (R) in performance (1) on the same task presented at different times (temporal repeatability), and (2) on different tasks that measured the same putative cognitive ability (contextual repeatability). We also addressed whether R estimates were influenced by seven extrinsic factors (moderators): type of cognitive performance measurement, type of cognitive task, delay between tests, origin of the subjects, experimental context, taxonomic class and publication status. We found support for both temporal and contextual repeatability of cognitive performance, with mean R estimates ranging between 0.15 and 0.28. Repeatability estimates were mostly influenced by the type of cognitive performance measures and publication status. Our findings highlight the widespread occurrence of consistent inter-individual variation in cognition across a range of taxa which, like behaviour, may be associated with fitness outcomes.This article is part of the theme issue ‘Causes and consequences of individual differences in cognitive ability’.
(400479) lillie Ferrier
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Anti-AIDS Agents 90. Novel C-28 Modified Bevirimat Analogues as Potent HIV Maturation Inhibitors
Creators: name: Bori, Ibrahim D.
name: Chen, Chin-Ho
name: Lee, Kuo-Hsiung
name: Qian, Keduo
name: Huang, Li
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: In a continuing study of bevirimat (2), the anti-HIV-maturation clinical trials agent, 28 new betulinic acid (BA, 1) derivatives were designed and synthesized. Among these compounds, 17, with a C-28 MEM ester moiety, and 22, with a C-28 ethyl hexanoate, increased the anti-HIV replication activity compared with 2 by two-fold, while compounds 40–41 and 48–49, with C-28 piperazine or piperidine amide substitutions, increased the activity by three- to fifteen-fold. The best new compound 41 exhibited an anti-HIV IC50 value of 0.0059 μM, compared with 0.087 μM for 2. All of the active compounds showed only anti-maturation effects, as confirmed by TZM-bl assay, in blocking the HIV replication. The results suggest that proper C-28 substitutions can further enhance the anti-maturation activity of 2, without any anti-entry effects. Thus, 41 may serve as a promising new lead for development of anti-AIDS clinical trial candidates.
On the scalar potential of two-Higgs doublet models
Creators: name: Chakraborty, Indrani
name: Kundu, Anirban
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We perform a detailed analysis of the Two-Higgs Doublet Model (2HDM) potential. At the tree-level, the potential may accommodate more than one minima, one of them being the electroweak (EW) minimum where the universe lives. The parameter space allowed after the data from the Large Hadron Collider (LHC) came in almost excludes those cases where the EW vacuum is shallower than the second minimum. We extend the analysis by including terms in the 2HDM potential that break the $Z_2$ symmetry of the potential by dimension-4 operators and show that the conclusions remain unchanged. Furthermore, a one-loop analysis of the potential is performed for both cases, namely, where the $Z_2$ symmetry of the potential is broken by dimension-2 or dimension-4 operators. For quantitative analysis, we show our results for the Type-II 2HDM, qualitative results remaining the same for other 2HDMs. We find that the nature of the vacua from the tree-level analysis does not change; the EW vacuum still remains deeper.
description: 21 pages, 10 figures, Published in Physical Review D, Title changed in the published version to "Scalar potential of two-Higgs doublet models"
Deep Instance Segmentation with Automotive Radar Detection Points
Creators: name: Liu, Jianan
name: Xiong, Weiyi
name: Bai, Liping
name: Xia, Yuxuan
name: Huang, Tao
name: Ouyang, Wanli
name: Zhu, Bing
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Automotive radar provides reliable environmental perception in all-weather conditions with affordable cost, but it hardly supplies semantic and geometry information due to the sparsity of radar detection points. With the development of automotive radar technologies in recent years, instance segmentation becomes possible by using automotive radar. Its data contain contexts such as radar cross section and micro-Doppler effects, and sometimes can provide detection when the field of view is obscured. The outcome from instance segmentation could be potentially used as the input of trackers for tracking targets. The existing methods often utilize a clustering-based classification framework, which fits the need of real-time processing but has limited performance due to minimum information provided by sparse radar detection points. In this paper, we propose an efficient method based on clustering of estimated semantic information to achieve instance segmentation for the sparse radar detection points. In addition, we show that the performance of the proposed approach can be further enhanced by incorporating the visual multi-layer perceptron. The effectiveness of the proposed method is verified by experimental results on the popular RadarScenes dataset, achieving 89.53% mean coverage and 86.97% mean average precision with the IoU threshold of 0.5, which is superior to other approaches in the literature. More significantly, the consumed memory is around 1MB, and the inference time is less than 40ms, indicating that our proposed algorithm is storage and time efficient. These two criteria ensure the practicality of the proposed method in real-world systems.
description: 11 pages, 9 figures, 3 tables, accepted by IEEE Transactions on Intelligent Vehicles
title: Большие акушерские синдромы: исходы для матери и новорожденного
Creators: name: ELS IPR BOOKS
Publisher: name: Саратовский государственный медицинский университет им. В.И. Разумовского
Year: 2021

description: В монографии раскрываются общие патогенетические механизмы возникновения акушерских осложнений, что позволило объединить их в одну группу больших акушерских синдромов. Для предупреждения рассматриваемой патологии, снижения ее частоты и тяжести предложено превентивное медикаментозное лечение и проведение занятий аквааэробикой во время беременности. Эффективность данного лечения определена по снижению частоты и тяжести акушерских осложнений для матери, плода и новорожденного с учетом изменения лабораторных показателей до и после превентивного лечения в сравнении с контролем. Для акушеров-гинекологов, неонатологов, педиатров, клинических ординаторов и аспирантов.
title: Диагностика заболеваний: основы теории и практики
Creators: name: ELS IPR BOOKS
Publisher: name: Саратовский государственный медицинский университет им. В.И. Разумовского
Year: 2019

description: Монография посвящена описанию основных вопросов теории и практики диагностики, методологии работы врача, способов и методов целенаправленной умственной деятельности по сбору и анализу информации. Отражены значимость и особенности клинического мышления на разных этапах диагностического процесса. Впервые в суммарном виде описаны структура диагностики заболеваний с учетом теории «развивающихся объектов», методология и фазы «интегративной диагностики», особенности моделирования коморбидных состояний. Представлены в форме программированного обучения ответы на вопросы пропедевтического характера, чаще всего встречающиеся во врачебной практике. Издание адресовано студентам медицинских вузов и врачам всех специальностей.
(400480) Thomas Ferrier
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Exponentially More Precise Quantum Simulation of Fermions in the Configuration Interaction Representation
Creators: name: Babbush, Ryan
name: Berry, Dominic W.
name: Sanders, Yuval R.
name: Kivlichan, Ian D.
name: Scherer, Artur
name: Wei, Annie Y.
name: Love, Peter J.
name: Aspuru-Guzik, Alán
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We present a quantum algorithm for the simulation of molecular systems that is asymptotically more efficient than all previous algorithms in the literature in terms of the main problem parameters. As in previous work [Babbush et al., New Journal of Physics 18, 033032 (2016)], we employ a recently developed technique for simulating Hamiltonian evolution, using a truncated Taylor series to obtain logarithmic scaling with the inverse of the desired precision. The algorithm of this paper involves simulation under an oracle for the sparse, first-quantized representation of the molecular Hamiltonian known as the configuration interaction (CI) matrix. We construct and query the CI matrix oracle to allow for on-the-fly computation of molecular integrals in a way that is exponentially more efficient than classical numerical methods. Whereas second-quantized representations of the wavefunction require $\widetilde{\cal O}(N)$ qubits, where $N$ is the number of single-particle spin-orbitals, the CI matrix representation requires $\widetilde{\cal O}(η)$ qubits where $η\ll N$ is the number of electrons in the molecule of interest. We show that the gate count of our algorithm scales at most as $\widetilde{\cal O}(η^2 N^3 t)$.
description: Complete rewrite (extended from 12 pages to 41 pages): results are now presented as formal proofs with clear assumptions
On the existence of Auslander-Reiten $n$-exangles in $n$-exangulated categories
Creators: name: He, Jian
name: Hu, Jiangsheng
name: Zhang, Dongdong
name: Zhou, Panyue
Publisher: name: arXiv
Year: 2021
Subjects: subject: Representation Theory (math.RT)
subject: Category Theory (math.CT)
subject: FOS: Mathematics

description: Let $\mathscr{C}$ be an $n$-exangulated category. In this note, we show that if $\mathscr{C}$ is locally finite, then $\mathscr{C}$ has Auslander-Reiten $n$-exangles. This unifies and extends results of Xiao-Zhu, Zhu-Zhuang, Zhou and Xie-Lu-Wang for triangulated, extriangulated, $(n+2)$-angulated and $n$-abelian categories, respectively.
description: 18 pages. arXiv admin note: substantial text overlap with arXiv:2109.12954; text overlap with arXiv:2108.07985, arXiv:2109.00196. text overlap with arXiv:2006.02223, arXiv:2011.00729, arXiv:1909.13284; text overlap with arXiv:1709.06689 by other authors
Antitumor Agents. 293. Nontoxic Dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylenedioxybiphenyl-2,2′-dicarboxylate (DDB) Analogues Chemosensitize Multidrug-Resistant Cancer Cells to Clinical Anticancer Drugs
Creators: name: Lee, Kuo-Hsiung
name: Bastow, Kenneth F.
name: Goto, Masuo
name: Nakagawa-Goto, Kyoko
name: Ohkoshi, Emika
name: Hung, Hsin-Yi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Novel dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylenedioxybiphenyl-2,2′-dicarboxylate (DDB) analogs were designed and synthesized to improve their chemosensitizing action on KBvin (vincristine resistant nasopharyngeal carcinoma) cells, a multi-drug resistant cell line over-expressing P-glycoprotein (P-gp). Structure-activity relationship analysis showed that aromatic and bulky aliphatic side chains at the 2,2′-positions effectively and significantly sensitized P-gp overexpressing multidrug resistant (MDR) cells to anticancer drugs, such as paclitaxel (TAX), vincristine (VCR), and doxorubicin (DOX). DDB derivatives 16 and 23 showed 5–10 times more effective reversal ability than verapamil (VRP) for TAX and VCR. Analog 6 also exhibited five times greater chemosensitizing effect against DOX than VRP. Importantly, no cytotoxicity was observed by the active DDB analogs against both non-MDR and MDR cells, suggesting that DDB analogs serve as the novel lead compounds for the development of chemosensitizers to overcome MDR phenotype. The mechanism of action studies demonstrated that effective inhibition of P-glycoprotein by DDB analogs dramatically elevated cellular concentration of anticancer drugs.
title: Забытый ревматизм (острая ревматическая лихорадка) и хроническая склеротическая болезнь
Creators: name: ELS IPR BOOKS
Publisher: name: Саратовский государственный медицинский университет им. В.И. Разумовского
Year: 2021

description: Монография посвящена описанию основных вопросов теории и практики одного из «забытых» (по формулировке ВОЗ – neglected diseases) заболеваний – острой ревматической лихорадки. Представлены современные данные этиологии, патогенеза, клиники, диагностики, лечения и профилактики. Рассматриваются классическая и измененные формы болезни, их распознавание с позиции интегративной диагностики и системного подхода. Делается акцент на особенностях клинического мышления на разных этапах работы врача. Предлагается несколько иной подход к классификации, вопросам коморбидности и определению места указанного заболевания в рамках хронической склеротической болезни. Для терапевтов, ревматологов и студентов медицинских вузов.
Nonlinear Landau damping and modulation of electrostatic waves in a nonextensive electron-positron-pair plasma
Creators: name: Chatterjee, D.
name: Misra, A. P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The nonlinear theory of amplitude modulation of electrostatic wave envelopes in a collisionless electron-positron (EP) pair plasma is studied by using a set of Vlasov-Poisson equations in the context of Tsallis' $q$-nonextensive statistics. In particular, the previous linear theory of Langmuir oscillations in EP plasmas [Phys. Rev. E {\bf87}, 053112 (2013)] is rectified and modified. Applying the multiple scale technique (MST), it is shown that the evolution of electrostatic wave envelopes is governed by a nonlinear Schr{ö}dinger (NLS) equation with a nonlocal nonlinear term $\propto {\cal{P}}\int|ϕ(ξ',τ)|^2dξ'ϕ/(ξ-ξ') $ [where ${\cal P}$ denotes the Cauchy principal value, $ϕ$ is the small-amplitude electrostatic (complex) potential, and $ξ$ and $τ$ are the stretched coordinates in MST] which appears due to the wave-particle resonance. It is found that a subregion $1/3
description: 25 pages, 5 figures; In the revised version typos are rectified, long expressions are given in the Appendices; this version to appear in Phys. Rev. E
Datasets methods, general methods and supplemental results from The repeatability of cognitive performance: a meta-analysis
Creators: name: M. Cauchoix
name: P. K. Y. Chow
name: J. O. Van Horik
name: C.M. Atance
name: EJ Barbeau
name: G. Barragan-Jason
name: P. Bize
name: A. Boussard
name: S. D. Buechel
name: A. Cabirol
name: L. Cauchard
name: N. Claidière
name: S. Dalesman
name: J. M. Devaud
name: M. Didic
name: B. Doligez
name: J. Fagot
name: C. Fichtel
name: J. Henke-Von Der Malsburg
name: E. Hermer
name: L. Huber
name: F. Huebner
name: P. M. Kappeler
name: S. Klein
name: J. Langbein
name: E. J. G. Langley
name: S. E. G. Lea
name: M. Lihoreau
name: H. Lovlie
name: L. D. Matzel
name: S. Nakagawa
name: C. Nawroth
name: S. Oesterwind
name: B. Sauce
name: E. Smith
name: E. Sorato
name: S. Tebbich
name: L. J. Wallis
name: M. A. Whiteside
name: A. Wilkinson
name: A. S. Chaine
name: J. Morand-Ferron
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour

description: Behavioural and cognitive processes play important roles in mediating an individual's interactions with its environment. Yet, while there is a vast literature on repeatable individual differences in behaviour, relatively little is known about the repeatability of cognitive performance. To further our understanding of the evolution of cognition, we gathered 44 studies on individual performance of 25 species across six animal classes and used meta-analysis to assess whether cognitive performance is repeatable. We compared repeatability (R) in performance (1) on the same task presented at different times (temporal repeatability), and (2) on different tasks that measured the same putative cognitive ability (contextual repeatability). We also addressed whether R estimates were influenced by seven extrinsic factors (moderators): type of cognitive performance measurement, type of cognitive task, delay between tests, origin of the subjects, experimental context, taxonomic class and publication status. We found support for both temporal and contextual repeatability of cognitive performance, with mean R estimates ranging between 0.15 and 0.28. Repeatability estimates were mostly influenced by the type of cognitive performance measures and publication status. Our findings highlight the widespread occurrence of consistent inter-individual variation in cognition across a range of taxa which, like behaviour, may be associated with fitness outcomes.This article is part of the theme issue ‘Causes and consequences of individual differences in cognitive ability’.
Chemocentric Informatics Approach to Drug Discovery: Identification and Experimental Validation of Selective Estrogen Receptor Modulators as Ligands of 5-Hydroxytryptamine-6 Receptors and as Potential Cognition Enhancers
Creators: name: Setola, Vincent
name: Tropsha, Alexander
name: Roth, Bryan L.
name: Hajjo, Rima
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: We have devised a chemocentric informatics methodology for drug discovery integrating independent approaches to mining biomolecular databases. As a proof of concept, we have searched for novel putative cognition enhancers. First, we generated Quantitative Structure- Activity Relationship (QSAR) models of compounds binding to 5-hydroxytryptamine-6 receptor (5HT6R), a known target for cognition enhancers, and employed these models for virtual screening to identify putative 5-HT6R actives. Second, we queried chemogenomics data from the Connectivity Map (http://www.broad.mit.edu/cmap/) with the gene expression profile signatures of Alzheimer’s disease patients to identify compounds putatively linked to the disease. Thirteen common hits were tested in 5-HT6R radioligand binding assays and ten were confirmed as actives. Four of them were known selective estrogen receptor modulators that were never reported as 5-HT6R ligands. Furthermore, nine of the confirmed actives were reported elsewhere to have memory-enhancing effects. The approaches discussed herein can be used broadly to identify novel drug-target-disease associations.
title: Лазерный эндоскопический гемостаз в хирургии кровоточащей гастродуоденальной язвы
Creators: name: ELS IPR BOOKS
Publisher: name: Саратовский государственный медицинский университет им. В.И. Разумовского
Year: 2021

description: В монографии обобщен более чем сорокалетний опыт сотрудников кафедры общей хирургии по лечению больных кровоточащей гастродуоденальной язвой. Весомая часть работы посвящена вопросам эндоскопического воздействия на источник кровотечения при самопроизвольной его остановке, а также эндоскопического гемостаза с использованием лазерной техники в условиях активного кровотечения из гастродуоденальной язвы. На основании экспериментальных данных об особенностях взаимодействия лазерного излучения с желудочной стенкой авторами разработана оригинальная методика лазерного эндоскопического гемостаза. Предназначена для клинических ординаторов, врачей-эндоскопистов и хирургов, занимающихся проблемами экстренной хирургии.
(400481) Janan Ferrier
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Design, Synthesis, and Preclinical Evaluations of Novel 4-Substituted 1,5-Diarylanilines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Drug Candidates
Creators: name: Xie, Lan
name: Lee, Kuo-Hsiung
name: Huang, Li
name: Zhu, Lei
name: Qian, Keduo
name: Sun, Lian-Qi
name: Qin, Bingjie
name: Chen, Chin Ho
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Twenty-one new 4-substituted diarylaniline compounds (DAANs) (Scheme 2, series 13, 14, and 15) were designed, synthesized, and evaluated against wild-type and drug resistant HIV-1 viral strains. As a result, approximately a dozen new DAANs showed high potency with low nano- to sub-nanomolar EC50 values ranging from 0.2 to 10 nM. The three most promising compounds 14e, 14h, and 15h exhibited high potency against wild-type and drug-resistant viral strains with EC50 values at the sub-nanomolar level (0.29–0.87 nM), and were comparable to or more potent than the new NNRTI drug riplivirine (2) in the same assays. Drug-like physicochemical property assessments revealed that the most active DAANs (EC50 1–90 μg/mL at pH 7.4 and pH 2) and metabolic stability in vitro than 2, as well as desirable log P values (2). These promising results warrant further development of this novel compound class as potential potent anti-AIDS clinical trial candidates.
title: Пандемия в обществе потребления: власть медицины в формировании нового социального порядка
Creators: name: ELS IPR BOOKS
Publisher: name: Саратовский государственный медицинский университет им. В.И. Разумовского
Year: 2021

description: В монографии изложены социально-философские, социально-экономические, исторические и психологические стороны проблемы формирования нового социального порядка в контексте пандемии COVID-19. Авторы исследуют социокультурные и исторические аспекты развития эпидемий, трансформации института медицины, медикализацию практик социального контроля, вопросы экспорта медицинских услуг в обществе потребления, институциональные изменения общества в целом. Предназначена для научных работников, аспирантов, всех интересующихся социальными проблемами современной медицины.
Direct observation of a Fermi liquid-like normal state in an iron-pnictide superconductor
Creators: name: Tytarenko, Alona
name: Huang, Yingkai
name: de Visser, Anne
name: Johnston, Steve
name: van Heumen, Erik
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: There are two prerequisites for understanding high-temperature (high-T$_c$) superconductivity: identifying the pairing interaction and a correct description of the normal state from which superconductivity emerges. The nature of the normal state of iron-pnictide superconductors, and the role played by correlations arising from partially screened interactions, are still under debate. Here we show that the normal state of carefully annealed electron-doped BaFe$_{2-x}$Co$_{x}$As$_2$ at low temperatures has all the hallmark properties of a local Fermi liquid, with a more incoherent state emerging at elevated temperatures, an identification made possible using bulk-sensitive optical spectroscopy with high frequency and temperature resolution. The frequency dependent scattering rate extracted from the optical conductivity deviates from the expected scaling $M_{2}(ω,T)\propto(\hbarω)^{2}+(pπk_{B}T)^{2}$ with $p\approx$ 1.47 rather than $p$ = 2, indicative of the presence of residual elastic resonant scattering. Excellent agreement between the experimental results and theoretical modeling allows us to extract the characteristic Fermi liquid scale $T_{0}\approx$ 1700 K. Our results show that the electron-doped iron-pnictides should be regarded as weakly correlated Fermi liquids with a weak mass enhancement resulting from residual electron-electron scattering from thermally excited quasi-particles.
description: 6+9pages, 3+9 figures To be published in Scientific Reports
Eigenvalues and cycles of consecutive lengths
Creators: name: Li, Binlong
name: Ning, Bo
Publisher: name: arXiv
Year: 2021
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: As the counterpart of classical theorems on cycles of consecutive lengths due to Bondy and Bollobás in spectral graph theory, Nikiforov proposed the following open problem in 2008: What is the maximum $C$ such that for all positive $\varepsilon\sqrt{\lfloor\frac{n^2}{4}\rfloor}$ contains a cycle of length $\ell$ for each integer $\ell\in[3,(C-\varepsilon)n]$. We prove that $C\geq\frac{1}{4}$ by a novel method, improving the existing bounds. Besides several novel ideas, our proof technique is partly inspirited by the recent research on Ramsey numbers of star versus large even cycles due to Allen, Łuczak, Polcyn and Zhang, and with aid of a powerful spectral inequality. We also derive an Erdős-Gallai-type edge number condition for even cycles, which may be of independent interest.
description: 6 pages, to appear in Journal of Graph Theory(2023). arXiv admin note: substantial text overlap with arXiv:2102.03855
Total synthesis of 4-((3S,5R)-3,5-dihydroxynonadecyl)phenol
Creators: name: Rajendar, Potham
name: Desikan, Srinivasa
name: Sridhar, Gattu
name: Tripuramallu, Bharat Kumar
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: An enantioselective total synthesis of novel gingerol-related compound 4-((3S,5R)-3,5-dihydroxynonadecyl)phenol, an anti-oxidant isolated from the resinous exudates of Chilean desert plants, has been accomplished from a known commercially available 4-(but-3-enyl) phenol by a concise ten-step sequence. In this synthesis, Sharpless asymmetric dihydroxylation, Grignard reaction and Iodine-induced electrophilic cyclization have been applied as key steps.
On the gonality of stable curves
Creators: name: Coelho, Juliana
name: Sercio, Frederico
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14H10, 14H51

description: In this paper we use admissible covers to investigate the gonality of a stable curve $C$ over $\mathbb{C}$. If $C$ is irreducible, we compare its gonality to that of its normalization. If $C$ is reducible, we compare its gonality to that of its irreducible components. In both cases we obtain lower and upper bounds. Furthermore, we show that four admissible covers constructed give rise to generically injective maps between Hurwitz schemes. We show that the closures of the images of three of these maps are components of the boundary of the target Hurwitz schemes, and the closure of the image of the remaining map is a component of a certain codimension-1 subscheme of the boundary of the target Hurwitz scheme.
description: 21 pages, 7 figures. irreducibility claim removed from Theorem 4.1
Table S1 and Figs S1-S4 from More than the sum of the parts: annual partitioning within spatial guilds underpins community regulation.
Creators: name: A. E. Magurran
name: P. A. Henderson
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: 10202 Biological Mathematics
subject: FOS: Mathematics

description: Table of guild members and additional information on the randomisation tests undertaken