cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Modulation of antibiotic activity by the hydroalcoholic extract from leaves of Caryocar coriaceum WITTM
Creators: name: Neto, Luís J. De Lacerda
name: A. G. B. Ramos
name: M. R. Kerntopf
name: H. D. M. Coutinho
name: L. J. Quintans-Junior
name: J. R. G. S. Almeida
name: J. Ribeiro-Filho
name: I. R. A. Menezes
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: The aim of this study was to identify the presence of tannins, phenols and flavonoids on the hydroalcoholic extract of Caryocar coriaceum leaves (HECCL) and to determine the antioxidant and antibacterial activity of this extract. The extract was tested alone (1024–1 μg/mL) or associated (MIC/8) with several antibiotics in order to identify any antibacterial activity against multiresistant bacterial strains (Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa). The existence of tannins, total phenols (901.31 mg/g) and flavonoids (89.68 mg/g) was confirmed in the HECCL. The presence of rutin and quercetin were confirmed by Thin-layer chromatography (TLC). Using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method, the antioxidant activity of the extract (9 μg/mL) was determined. Moreover, the Minimum Inhibitory Concentration (MIC) value found for HECCL was 1024 μg/mL and the association between HECCL (MIC/8) with benzylpenicillin significantly changed its minimum inhibitory concentration from 2500 to 625 μg/mL against E. coli.
Sleep Quality and Emotion Regulation Success and Strategy Use Across the Adult Lifespan
Creators: name: Lindquist, Kristen A.
name: Frye, Natalie G.
name: Fan, Jennifer
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2025

description:
Previous research has shown that sleep and age impact emotion regulation success. Sleep decrements are known to occur with increasing age, yet little research has examined how alterations to sleep quality with increasing age impact emotion regulation efficacy. Using data from 109 adults aged 18-83 (Mage= 48.7, 56% female), the present study investigated the effects of sleep quality, age, and their interaction on self-reported emotion regulation success and functional connectivity between the amygdala and the dorsolateral prefrontal cortex (dlPFC), dorsomedial prefrontal cortex (dmPFC), and ventrolateral prefrontal cortex (vlPFC) during an emotion regulation task. Moreover, this study explored moderation by emotion regulation strategy, as strategy choice has been found to differ with age. Greater age was associated with worse self-reported emotion regulation success, and better short-term sleep quality predicted greater functional connectivity between the dmPFC and amygdala in adults 47 and older. While there was no moderation by emotion regulation strategy, we found that reappraisal was less successful compared to other strategies. These findings emphasize the importance of good quality sleep for emotion regulation, particularly for older adults, and offer insight into its neural mechanisms across the adult lifespan.
Identification and in vitro antioxidant activities of phenolic compounds isolated from Cynoglossum cheirifolium L.
Creators: name: Bensaid Ilhem
name: Atik Bekkara Fawzia
name: Abdelhamid, El Haci Imad
name: Belarbi Karima
name: Beddou Fawzia
name: Bekhechi Chahrazed
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: In an extensive search for bioactive compounds from plant sources, the quantitative and qualitative characterisation of the compounds present in Cynoglossum cheirifolium extracts was studied. Total phenolic and flavonoid contents were determined by spectrophotometric techniques. In vitro antioxidant and radical scavenging profiling was determined through DPPH• scavenging activity and Ferric reducing antioxidant power (FRAP). Our study showed that leaves produce more phenolic compounds, followed by flowering aerial part. The butanolic fraction obtained from leaves extract exhibited the highest total phenolics (78.65 ± 3.58 mg GAE/g DW) and flavonoids (22.15 ± 4.66 mg CE/g DW). In contrast, this fraction displayed the highest DPPH• scavenging ability with IC50 values of 0.06 ± 0.003 mg/mL. The RP-HPLC-PDA analysis of phenolic compounds from leaves of C. cheirifolium lets to identify: rosmarinic acid, ferulic acid, caffeic acid, p-coumaric acid, syringic acid, sinapic acid and rutin. The obtained results indicate that this plant represent a valuable source of natural antioxidants.
The case for open Open Access book infrastructures
Creators: name: Adema, Janneke
name: Deville, Joe
Publisher: name: Zenodo
Year: 2022
Subjects: open access
monographs
infrastructures
community-led

description: A presentation held by Janneke Adema and Joe Deville as part of the Research & Scholarly Publishing Forum panel “Open books under the microscope” – examining the transition to open scholarship in the world of books & monographs" that took place at the London Book Fair 2022 on April 07, 2022. Learning outcomes: How do we ‘open’ books successfully? What models are working and what lessons have we learned. Hear about what a transition to ‘open’ looks like from a variety of publishers producing books and monographs including ‘flip’ case-studies. Find out more about how infrastructure is enabling shifts towards open.
description: Community-led Open Publishing Infrastructures for Monographs (COPIM) is supported by the Research England Development (RED) Fund, and Arcadia—a charitable fund of Lisbet Rausing and Peter Baldwin.
pretrained models for 3D semantic image segmentation with InteractiveNet
Creators: name: Douwe J. Spaanderman
name: Martijn P. A. Starmans
name: Stefan Klein
Publisher: name: Zenodo
Year: 2023

description: InteractiveNet is a self-configuring minimally interactive pipeline for medical image segmentation. We pretrained InteractiveNet for several applications. This repository contains the trained network parameters for these datasets. Instructions for how to use them are provided at: https://github.com/Douwe-Spaanderman/InteractiveNet
Supplementary Tables & Figures from TSNAD: an integrated software for cancer somatic mutation and tumour-specific neoantigen detection
Creators: name: Zhou, Zhan
name: Lyu, Xingzheng
name: Wu, Jingcheng
name: Yang, Xiaoyue
name: Wu, Shanshan
name: Zhou, Jie
name: Gu, Xun
name: Su, Zhixi
name: Chen, Shuqing
Publisher: name: The Royal Society
Year: 2017

description: The supplementary material includes four tables and two figures
Blow-ups of three-dimensional toric singularities
Creators: name: Kudryavtsev, S. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: The purely log terminal blow-ups of three-dimensional terminal toric singularities are described. The three-dimensional divisorial contractions $f\colon (Y,E)\to (X\ni P)$ are described provided that $\Exc f=E$ is an irreducible divisor, $(X\ni P)$ is a toric terminal singularity, $f(E)$ is a toric subvariety and $Y$ has canonical singularities.
description: In memory of Vasily Iskovskikh, errors are corrected
Supplementary materials for optimal localization of diffusion sources in complex networks from Optimal localization of diffusion sources in complex networks.
Creators: name: Hu, Zhao-Long
name: Han, Xiao
name: Lai, Ying-Cheng
name: Wang, Wen-Xu
Publisher: name: The Royal Society
Year: 2017

description: Locating sources of diffusion and spreading from minimum data is a significant problem in network science with great applied values to the society. However, a general theoretical framework dealing with optimal source localization is lacking. Combining the controllability theory for complex networks and compressive sensing, we develop a framework with high efficiency and robustness for optimal source localization in arbitrary weighted networks with arbitrary distribution of sources. We offer a minimum output analysis to quantify the source locatability through a minimal number of messenger nodes that produce sufficient measurement for fully locating the sources. When the minimum messenger nodes are discerned, the problem of optimal source localization becomes one of sparse signal reconstruction, which can be solved using compressive sensing. Application of our framework to model and empirical networks demonstrates that sources in homogeneous and denser networks are more readily to be located. A surprising finding is that, for a connected undirected network with random link weights and weak noise, a single messenger node is sufficient for locating any number of sources. The framework deepens our understanding of the network source localization problem and offers efficient tools with broad applications.
Supplementary materials for optimal localization of diffusion sources in complex networks from Optimal localization of diffusion sources in complex networks
Creators: name: Hu, Zhao-Long
name: Han, Xiao
name: Lai, Ying-Cheng
name: Wang, Wen-Xu
Publisher: name: The Royal Society
Year: 2017

description: Locating sources of diffusion and spreading from minimum data is a significant problem in network science with great applied values to the society. However, a general theoretical framework dealing with optimal source localization is lacking. Combining the controllability theory for complex networks and compressive sensing, we develop a framework with high efficiency and robustness for optimal source localization in arbitrary weighted networks with arbitrary distribution of sources. We offer a minimum output analysis to quantify the source locatability through a minimal number of messenger nodes that produce sufficient measurement for fully locating the sources. When the minimum messenger nodes are discerned, the problem of optimal source localization becomes one of sparse signal reconstruction, which can be solved using compressive sensing. Application of our framework to model and empirical networks demonstrates that sources in homogeneous and denser networks are more readily to be located. A surprising finding is that, for a connected undirected network with random link weights and weak noise, a single messenger node is sufficient for locating any number of sources. The framework deepens our understanding of the network source localization problem and offers efficient tools with broad applications.
Yangonindimers A-C, three new kavalactone dimers from Piper methysticum (kava)
Creators: name: Song, Jia-Ling
name: Li, Bai-Lin
name: Yuan, Yao
name: Nie, Ling-Hui
name: Niu, Jia
name: Chiu, David
name: Xu, Zhi-Fang
name: Wu, Jie-Wei
name: Qiu, Sheng-Xiang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Three new kavalactone dimers, designated as yangonindimers A-C (1–3), along with one known analogue were isolated from the roots of Piper methysticum. Their structures were elucidated via extensive analysis of their 1D, 2D NMR and mass spectroscopic data. All these dimers possess a skeleton featuring a cyclobutane ring connecting two kavalactone units. Compounds 1–4 were evaluated for their cytotoxic activities against human tumour cell lines NCI-H46, SW480 and HepG2, but none showed significant activity.
Hepatoprotective effect against CCl4-induced acute liver damage in mice and High-performance liquid chromatography mass spectrometric method for analysis of the constituents of extract of Rubus crataegifolius
Creators: name: Sun, Yongjiao
name: Jia, Lingyun
name: Huang, Zhanbo
name: Wang, Jing
name: Lu, Jincai
name: Li, Jing
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: This study is an attempt to evaluate the hepatoprotective activity of Rubus Crataegifolius against carbon tetrachloride-induced liver injury in mice. 70% ethanolic, ethyl acetate and n-BuOH extract of R. crataegifolius were administered daily for 14 days in experimental animals before they were treated with CCl4. The hepatoprotective activity of the extracts in this study was compared with the reference drug silymarin. A high-performance liquid chromatography mass spectrometric (HPLC-EIS-MS/MS) method was developed for the determination of the constituents of the extracts. According to the data of HPLC-EIS-MS/MS, the chemical structures of the largely 14 constituents of R. crataegifolius were identified online without time-consuming isolation. Ethyl acetate extracts of R. crataegifolius showed strong antioxidant activities and significant protective effect against acute hepatotoxicity induced by CCl4. According to the data of HPLC-EIS-MS/MS, Oleanic acid, Phlorizin dehydrate and Quercetin-3-rhamnoside are considered as the main hepatoprotective factor in ethyl acetate extract.
Comparison of different methods for extraction of Cinnamomi ramulus: yield, chemical composition and in vitro antiviral activities
Creators: name: Zhou, Jing
name: Yuan, Xiurong
name: Li, Ling
name: Zhang, Tong
name: Wang, Bing
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences
subject: Virology

description: Hydrodistillation (HD), supercritical fluid extraction (SFE) and reflux extraction (RE) were applied to obtain Cinnamomi ramulus extracts. The yields, chemical compositions and antiviral activities of the extracts were investigated. Extracts were analysed using gas chromatography–mass spectrometry and the antiviral activities were evaluated using cytopathic effect inhibition assay. HD, SFE and RE afforded 0.376, 1.227 and 5.914% yields, respectively. Cinnamaldehyde (CA), SFE and ethanol extracts exhibited antiviral activities against herpes simplex virus type 1. Moreover, CA and other three extracts had inhibition efficacy against respiratory syncytial virus. The most efficient antiviral activities were obtained with SFE.
Benzimidazolyl based Schiff base palladium complex in an ionic liquid: an effective combination for Suzuki coupling
Creators: name: Vasantha Kumar Basappa Chidananda
name: Dileep Ramakrishna
name: Manpreet Kaur
name: Revanasiddappa Hosakere Doddarevanna
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: A new benzimidazole based Pd(II) Schiff base complex was prepared and its catalytic activity was evaluated for Suzuki cross-coupling reactions in ethyl-methyl imidazolium hexafluorophosphate [EMIM PF6] ionic liquid at ambient temperature. The system provides a stable and reusable method for coupling reactions. Optimization for suitable reaction conditions were studied with respect to the effect of catalyst concentration, effects of additives, solvent and substituents on boronic acid. Good to excellent yields were achieved using a modest amount of the catalyst. The reaction time was less and the yield was more compared to previously reported results. In addition, the catalyst can be easily reused and recycled for six times without much loss in activity; this is an example of sustainable and green methodology.
Two new phenolic glycosides from the stem of Zanthoxylum armatum DC
Creators: name: Guo, Tao
name: Dai, Li-Ping
name: Tang, Xiao-Feng
name: Song, Tong-Tong
name: Wang, Ya
name: Zhao, Ai-Hong
name: Cao, Ying-Ying
name: Chang, Jun
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Developmental Biology
subject: Cancer

description: Two new phenolic glycoside, 2-methoxy-4-hydroxylphenyl-1-O-α-L-rhamnopyranosyl- (1″ → 6′)-β-D-glucopyranoside. (1) and threo-3-methoxy-5-hydroxy-phenylpropanetriol-8-O-β-D-glucopyranoside (2), were isolated from the stems of Zanthoxylum armatum. The compounds 1 and 2 showed weak scavenging activity in DPPH free radical assay with IC50 values of 323 and 114 mM, respectively.
An Interview with Edmund Keeley
Creators: name: Vardoulakis, Dimitris
Publisher: name: Monash University
Year: 2017
Subjects: subject: 200599 Literary Studies not elsewhere classified
subject: FOS: Languages and literature

description: Any English reader interested in Greek literature inevitably comes across Edmund Keeley. The director of the Hellenic Studies Program at Princeton University until seven years ago when he retired has done much to make Greek poetry known. His exemplar translations of Kostantinos Cavafy, George Seferis, Agelos Sikelianos, Giannis Ritsos and Odysseas Elytis helped to establish a reputation in English speaking countries of the great Greek poetry of the 20th century.
Taxanes from Taxus wallichiana var. mairei cultivated in the southern area of the Yangtze River in China
Creators: name: Lun, Bo-Shu
name: Shao, Li-Wei
name: Wang, Yong
name: Li, Cong-Cong
name: Yu, Hua
name: Wang, Chun-Hua
name: Zhu, Yan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: A new and 25 known taxane diterpenoids were isolated from the dried whole plants of Taxus wallichiana var. mairei cultivated in the southern area of the Yangtze River in China. The chemical structure of new compound 1, named taxiwallinine, was established by means of MS and NMR analyses. Among the 25 known taxane compounds 2–26, compounds 10, 12, 14, 15, 17 and 21–23 were first isolated from this plant. Taxiwallinine and taxol were screened for the cytotoxic effect on human breast cancer cell line MCF-7 with IC50 values of 20.898 μg/mL and 0.008 μg/mL, respectively. Taxiwallinine showed moderate cytotoxicity to this cell line. These results demonstrate that T. wallichiana var. mairei cultivated in the southern area of the Yangtze River in China could be a renewable resource for extracting the taxane derivatives and the new compound, taxiwallinine, could be a potential anti-tumour product.
Scaling OpenSimulator : An Examination of Possible Architectures for an Internet­Scale Virtual Environment Network
Creators: name: Clark-Casey, Justin
Publisher: name: figshare
Year: 2017
Subjects: subject: 80111 Virtual Reality and Related Simulation
subject: FOS: Computer and information sciences
subject: Distributed Computing
subject: 80501 Distributed and Grid Systems

description: This dissertation describes an analysis of possible architectures for an Internet­scale virtual
environment network. These are treated as evolutions of an existing virtual environment
architecture embodied in an open­source project called OpenSimulator. Distributed computing
concepts and Z schemas are used to examine both the existing OpenSimulator architecture and the
alternative configurations.
Physical Inactivity among Adults in Malaysia: Findings from National Health and Morbidity Survey (NHMS) 2019
Creators: name: Alias, Nazirah
name: Kuay, Lim Kuang
name: Ying, Chan Ying
name: Ahzairin Ahmad
name: Ridwan Sanaudi
Publisher: name: Zenodo
Year: 2020
Subjects: National Health and Morbidity Survey
NHMS
2019
Physical Inactivity
Adults
Malaysia
FIndings

description: Introduction Physical inactivity was identified as the fourth leading risk factor for worldwide mortality with major implications towards general health including prevalence of noncommunicable diseases (NCDs) such as cardiovascular disease, diabetes, cancer and NCDs risk factor such as raised blood pressure, raised blood sugar and overweight . Monitoring the level of physical inactivity may reduce the disease burden, evaluate the effectiveness of current programme and as a guide for future planning. Objective This study aimed to determine the prevalence of physical inactivity among adults aged 16 years and above in Malaysia. Methodology Data was obtained from adults aged 16 years (n= 10,767) and above from the National Health and Morbidity Survey (NHMS) 2019, a cross sectional, population-based survey using a two- stage stratified random sampling design. Respondents were interviewed using a short version of International Physical Activity Questionnaire (IPAQ) . An individual with any combination total score of Metabolic Equivalents score (MET-minutes/week) from walking, moderate-intensity physical activity or vigorous-intensity physical activity which is lower than 600 METs minute a week were considered as physically inactive. Data were analysed by complex sampling descriptive analysis using SPSS version 26. Results [Refer to Poster]. Conclusion It is important to encourage younger generations to be physically active during adolescence and young adulthood, as this may be predictive for their cardiovascular risk profile and lipid related risk later in life. Specific and appropriate intervention programmes towards specific targeted group should be establish to increase the level of physical activity and to promote an active living towards an active and healthy Malaysia as vision in National Strategic Plan for Active Living (NASPAL) 2017 – 2025
title: Determining Effectiveness of New Approaches to Dengue Vector Control in Cambodia
Creators: name: Hustedt, John
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2021

description: Background: Dengue is an important public health problem with an estimated 390 million infections annually worldwide, and an estimated 1.6 million infections annually in Cambodia. Due to the rise in dengue cases, and the current lack of widely available effective vaccines and therapeutics there is an urgent need to come up with more effective, sustainable, and locally appropriate vector control methods. Methods: A cluster randomized trial with three arms was designed to assess the impact of guppy fish (Poecilia reticulata), in combination with the larvicide pyriproxyfen (PPF), and Communication for Behavioural Impact (COMBI) activities, on entomological indices over one year in Cambodia. In addition, entomology data was used to determine the ability of the Premise Condition Index (PCI) to predict Aedes mosquito density and prioritize vector control interventions. Results: The guppy only intervention arm was able to decrease the number of Aedes females (Density Ratio (DR)=0.49) and Pupae Per Person (DR=0.56) by roughly half compared to the control arm. There were no statistical differences identified between the two intervention arms. All other entomological indices showed similar statistically significant reductions in intervention arms compared to the control arm. Data from the KAP and qualitative assessments showed community acceptance of interventions. Despite statistically significant associations between PCI scores and adult and immature Aedes densities, receiver operating characteristic curves suggest the PCI was a poor predictor of whether premises had higher densities of immature and adult Aedes mosquitoes. Conclusions: The effectiveness of interventions demonstrated in the trial along with community acceptance suggests guppies should be considered as vector control tools in Cambodia as long as the benefits outweigh any potential environmental concerns. The PCI results suggest caution is warranted in programmatic use of PCI in areas of similar geography and mosquito abundance.
Ordering minimalist bridged polysilsesquioxane films under visible LED light irradiation
Creators: name: Ni, Lingli
name: Wu, Mei
name: Chen, Feng
name: Deroche, Irena
name: Chemtob, Abraham
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Mental Health

description: A visible light-mediated sol–gel process can promote the ordering of hexylene, octylene, and decylene-bridged polysilsesquioxane (SQ) with very simple organosilane building blocks having only a short alkylene bridging group: (CH3O)3SiCnH2nSi(OCH3)3 (n = 6, 8, 10). Photocondensation and self-assembly of films are promoted through exposure to a light-emitting diode (LED; 405 nm). The solvent-free synthesis involves very low light intensity (0.1 mW/cm2) and a minimum amount of photoacid generator (PAG; 0.5 wt%) acting as a photocatalyst. X-ray diffraction (XRD) and scanning electron microscopy (SEM) prove the high level of organization, while real-time Fourier transform infrared spectroscopy shows conformational ordering of alkylene chains throughout irradiation. Molecular modeling reveals a multilayer structure based on the stacking of a single polysiloxane chain, with organic groups attached to adjacent Si atoms showing up and down orientation.
Individual- and Organization-Level Work-to-Family Spillover Are Uniquely Associated with Hotel Managers' Work Exhaustion and Satisfaction
Creators: name: Lee, Soomi
name: Davis, Kelly D.
name: Neuendorf, Claudia
name: Grandey, Alicia
name: Lam, Chun Bun
name: Almeida, David M.
Publisher: name: Humboldt-Universität zu Berlin
Year: 2016
Subjects: subject: conservation of resources theory
subject: emotional exhaustion
subject: hotel industry
subject: job satisfaction
subject: organizational climate
subject: work-to-family spillover
subject: 150 Psychologie

description: Purpose: Building on the Conservation of Resources theory, this paper examined the unique and interactive associations of negative and positive work-to-family spillover (NWFS and PWFS, respectively) at the individual and organizational level with hotel managers' work exhaustion and satisfaction, beyond job demands and supervisors' leadership style. Design/Methodology/Approach: Guided by the levels of analysis framework, we first tested the unique associations of NWFS and PWFS with emotional exhaustion and job satisfaction at the individual level (571 hotel managers), beyond job demands supervisors' leadership style. Second, using multilevel modeling, we tested the climate effects of NWFS and PWFS on emotional exhaustion and job satisfaction aggregated at the organizational level (41 hotels). Third, we examined the role of the organizational climate of PWFS in the associations of individual-level NWFS with emotional exhaustion and job satisfaction. Findings: Beyond the effects of psychological job demands and supervisor's transformational leadership, at the individual level, hotel managers who experienced higher NWFS than other managers reported more exhaustion and lower job satisfaction, whereas those with higher PWFS reported less exhaustion and higher satisfaction. At the organizational level, working in hotels where the average level of NWFS was higher than other hotels was associated with feeling more exhaustion of the individual members; working in hotels with higher PWFS was associated with feeling less exhaustion. The negative link between individual-level NWFS and job satisfaction was buffered when organization-level PWFS was higher, compared to when it was lower. Originality/Value: This study moves beyond a focus on traditional job characteristics, toward considering individual and organizational experiences in the work-family interface as unique predictors of work exhaustion and satisfaction. Strengths of the study include illuminating organizational work-family climate effects such that coworkers' shared experiences of NWFS and PWFS explain individual members' work exhaustion, beyond their own experiences of spillover. The results also highlight that a high level of organizational PWFS can buffer the negative effects of individual NWFS.
Ordering Minimalist Bridged Polysilsesquioxane Films under Visible LED Light Irradiation
Creators: name: Ni, Lingli
name: Wu, Mei
name: Chen, Feng
name: Deroche, Irena
name: Chemtob, Abraham
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: A visible light-mediated sol-gel process can promote the ordering of hexylene, octylene and decylene-bridged polysilsesquioxane with very simple organosilane building blocks having only a short alkylene bridging group: (CH3O)3SiCnH2nSi(OCH3)3 (n = 6, 8, 10). Photocondensation and self-assembly of films are promoted through exposure to a light-emitting diode (405 nm). The solvent-free synthesis involves very low light intensity (0.1 mW/cm2) and a minimum amount of photoacid generator (0.5 wt%) acting as photocatalyst. X-ray diffraction and scanning electron microscopy prove the high level of organization, while real-time Fourier transform infrared spectroscopy shows conformational ordering of alkylene chains throughout irradiation. Molecular modeling reveals a multilayer structure based of the stacking of a single polysiloxane chain, with organic groups attached to adjacent Si atoms showing up and down orientation.
Use of the Meta-analysis and Kolmogorov Criteria in the Finding of Singularities of a Nuclear Matter Created in Ultra Relativistic Nuclear Collisions
Creators: name: Kizka, V. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Published theoretical data from several models: PHSD and HSD both with and without chiral symmetry restoration (CSR), applied to experimental data on nuclear collisions from BEVALAC and SIS to LHC energies were analyzed using meta-analysis and Kolmogorov criteria. This made it possible to localize possible features of nuclear matter created in central nucleus-nucleus collisions. Ignition of a drop of quark-gluon plasma (QGP) begins already at an energy of about $\sqrt{s_{NN}}$ = 2 GeV. We estimate that this QGP droplet occupies a small fraction, 15 $\%$ (average radius of about 5.3 fermi if the fireball radius is 10 fermi) of the total volume of the fireball created at $\sqrt{s_{NN}}$ = 2.7 GeV. A drop of exotic matter undergoes a split phase transition: separated boundaries of sharp (1st order) crossover and CSR in chiral limit, between QGP and Quarkyonic matter at an energy about $\sqrt{s_{NN}}$ = 3.5 GeV. The critical endpoint of 2nd order probably cannot be reached in nuclear collisions. The triple phase area occupies interval from $\sqrt{s_{NN}}$ = 12 GeV to 15 GeV, the critical endpoint of 1st order at around $\sqrt{s_{NN}}$ = 20 GeV. The boundary of smooth (2nd order) crossover transition with CSR in chiral limit between Quarkyonic matter and QGP was localized between $\sqrt{s_{NN}}$ = 9.3 GeV and 12 GeV, and between Hadronic and QGP in the interval from $\sqrt{s_{NN}}$ = 15 GeV to 20 GeV, the boundary of sharp (1st order) crossover transition with CSR in chiral limit between Hadronic matter and QGP was localized after $\sqrt{s_{NN}}$ = 20 GeV. The phase trajectory of the hadronic corona, enveloping the exotic droplet, always remains in the hadronic phase.
description: 13 pages, 6 figures, improved explanation and argumentation, published in the journal
Effects of surface charge of low molecular weight heparin-modified cationic liposomes on drug efficacy and toxicity
Creators: name: Li, Haohuan
name: Chen, Yi
name: Deng, Yueyang
name: Wang, Yue
name: Ke, Xue
name: Ci, Tianyuan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biochemistry
Space Science
Medicine
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Computational Biology

description: Cationic liposome is a potential nanocarrier to deliver drugs to solid tumor with proven efficiency in targeting tumor tissues. However, the major limitation is their charge-related instability and blood toxicity via intravenous injection. In order to overcome these problems and to maintain tumor targeting potency, we modified the cationic liposomes with low molecular weight heparin (LMWH) to obtain series of liposomes with different surface charges. Both in vitro and in vivo studies including serum stability, blood hemolysis, cellular uptake, cytotoxicity and in vivo biodistribution were evaluated. The results indicated the cationic liposome with surface charge of 5 mV (denoted as LLip-C) had the similar stability in serum and mild hemocytolysis compared with that of anionic liposome (LLip-D), but better cellular uptake owing to electrostatic interaction between cationic liposomes and cell membranes. Furthermore, we prepared curcumin-loaded liposomes to investigate the therapy efficiency. The intracellular distribution of curcumin-loaded LLip-C (Curcumin-LLip-C) was inclined to locate in cytoplasm and nuclei than curcumin-loaded LLip-D (Curcumin-LLip-D). In vitro cytotoxicity of Curcumin-LLip-C also exhibited higher inhibition of tumor cells than that of Curcumin-LLip-D. These results certified that a slightly positive surface charge of nanocarriers could achieve the balance between well antitumor efficiency and mild adverse effects.
An adaptive sampling method for variable-fidelity surrogate models using improved hierarchical kriging
Creators: name: Hu, Jiexiang
name: Zhou, Qi
name: Jiang, Ping
name: Shao, Xinyu
name: Xie, Tingli
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Mathematical Sciences not elsewhere classified

description: Variable-fidelity (VF) modelling methods have been widely used in complex engineering system design to mitigate the computational burden. Building a VF model generally includes two parts: design of experiments and metamodel construction. In this article, an adaptive sampling method based on improved hierarchical kriging (ASM-IHK) is proposed to refine the improved VF model. First, an improved hierarchical kriging model is developed as the metamodel, in which the low-fidelity model is varied through a polynomial response surface function to capture the characteristics of a high-fidelity model. Secondly, to reduce local approximation errors, an active learning strategy based on a sequential sampling method is introduced to make full use of the already required information on the current sampling points and to guide the sampling process of the high-fidelity model. Finally, two numerical examples and the modelling of the aerodynamic coefficient for an aircraft are provided to demonstrate the approximation capability of the proposed approach, as well as three other metamodelling methods and two sequential sampling methods. The results show that ASM-IHK provides a more accurate metamodel at the same simulation cost, which is very important in metamodel-based engineering design problems.
Three new isobenzofurans from the roots of Nicotiana Tabacum and their bioactivities
Creators: name: He, Pei
name: Yang, Peisong
name: Tang, Shiyun
name: Ye, Ling
name: Liu, Chunbo
name: Shen, Qinpeng
name: Tang, Dangyu
name: Zhang, Fengmei
name: Liu, Zhihua
name: Chen, Yongkuan
name: Yao, Shouzhuo
name: Xiang, Nengjun
name: Huang, Zhangjie
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Three new isobenzofurans (1–3), together with four known phenylpropanoids (4–7) were isolated from the roots of Nicotiana tabacum. Their structures were determined by means of HRESIMS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1–6 were tested for their anti-tobacco mosaic virus (anti-TMV) activities and cytotoxicity activities. The results showed that compounds 5 and 6 exhibited high anti-TMV activities with inhibition rates of 35.1 and 33.4%, respectively. The cytotoxicities of compounds 1–7 against five human tumor cell lines (NB4, A549, SHSY5Y, PC3 were also tested. Compounds 1–7 showed weak inhibitory activities against some tested human tumor cell lines with IC50 values in the range of 3.8–9.6 μM.
Trust the process: citizen participation and procedural legitimacy in constitutional change
Creators: name: Cozza, Joseph Francesco
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Using an original survey experiment, this study tests the impact of different constitutional amendment processes on the procedural legitimacy of constitutional change in the United States. In doing so, I separate the processes of amendment initiation and ratification, examining the role of legislatures, referendums, and citizens’ assemblies in legitimating both ordinary and revolutionary constitutional change. The results suggest that citizens confer greater procedural legitimacy on amendments proposed by a legislature and adopted via referendum, especially when the amendment is seen as revolutionary. This finding holds for when supporters of an amendment are excluded from the analysis. The results of this study have significant implications for the way in which democracies approach questions of fundamental constitutional change.
Two new terpenoids from Kalimeris indica
Creators: name: Wang, Guo-Kai
name: Yu, Yang
name: Wang, Zheng
name: Cai, Bai-Xiang
name: Zhou, Zhong-yu
name: Wang, Gang
name: Liu, Jin-Song
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: A new nor-sesquiterpene kalimeristone A (1), a new nor-triterpenoid kalimerislactone B (2) and eight known compounds 7-hydroxy-4′methoxyisoflavone (3), episyringaresinol (4), epipinoresinol (5), rhamnetin (6), vanillin (7), p-hydroxybenzaldehyde (8), syringic acid (9) and 3, 4-dihydroxybenzaldehyde (10) were isolated from the herbs of Kalimeris indica. The structures of these compounds were elucidated using spectroscopic techniques, such as NMR and MS. All of the compounds were isolated from this genus for the first time. The cytotoxicities against four cancer cell lines were evaluated in vitro, but were inactive.
A new benzophenone glycoside from the leaves of Mitracarpus villosus
Creators: name: Ngwoke, Kenneth G.
name: Orame, Njideka
name: Liu, Shuai
name: Okoye, Festus B. C.
name: Daletos, Georgios
name: Proksch, Peter
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: A new benzophenone glycoside, mitraphenone A (1), together with three known compounds (2–4) were isolated from the leaves of the traditionally used medicinal plant Mitracarpus villosus (Rubiaceae) collected in Nigeria. A combination of one- and two-dimensional NMR spectroscopic and mass spectrometric measurements were carried out to identify the structure of 1. All isolated compounds (1–4) were screened for their antibacterial activity against several Gram-positive and Gram-negative bacteria. Compound 1 exhibited moderate activity against Enterococcus faecium (strains ATCC 35667 and ATCC 700221) and Staphylococcus aureus ATCC 25923 with MIC values ranging from 25 to 50 μM.
A new iridoid glycoside and a new cinnamoyl glycoside from Scrophularia ningpoensis Hemsl
Creators: name: Zhang, Jun
name: C. F. Ip, Fanny
name: Liang, Yan
name: Y. Ip, Nancy
name: Zhong, Ba-Lian
name: Lai, Chun-Wang
name: Xu, Shi-Hai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: A new iridoid glycoside, namely 8-O-(threo-2, 3-dihydroxyl-3-phenyl-propionoyl)-harpagide (1), along with a new cinnamoyl glycoside named as cis-sibirioside A (2), were isolated from Scrophularia ningpoensis Hemsl. Their chemical structures were completely established by spectroscopic methods and comparison with related literatures. Compound 1 exhibited moderate antifouling effect against the settlement of Balanus amphitrite larvae with IC50 being 13.5 μg/mL and LC50 > 25 μg/mL.
Collections of parabolic orbits in homogeneous spaces, homogeneous dynamics and hyperkahler geometry
Creators: name: Amerik, Ekaterina
name: Verbitsky, Misha
Publisher: name: arXiv
Year: 2016
Subjects: subject: Algebraic Geometry (math.AG)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 14E30, 53C26

description: Let $M$ be a hyperkähler manifold with $b_2(M)\geq 5$. We improve our earlier results on the Morrison-Kawamata cone conjecture by showing that the Beauville-Bogomolov square of the primitive MBM classes (i.e. the classes whose orthogonal hyperplanes bound the Kähler cone in the positive cone, or, in other words, the classes of negative extremal rational curves on deformations of $M$) is bounded in absolute value by a number depending only on the deformation class of $M$. The proof uses ergodic theory on homogeneous spaces.
description: 12 pages, LaTeX
Physiological Data: Challenges for Privacy and Ethics
Creators: name: Davis, Keith
name: Ruotsalo, Tuukka
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences
subject: K.4.0; K.4.1; K.4.2

description: Wearable devices that measure and record physiological signals are now becoming widely available to the general public with ever-increasing affordability and signal quality. The data from these devices introduce serious ethical challenges that remain largely unaddressed. Users do not always understand how these data can be leveraged to reveal private information about them and developers of these devices may not fully grasp how physiological data collected today could be used in the future for completely different purposes. We discuss the potential for wearable devices, initially designed to help users improve their well-being or enhance the experience of some digital application, to be appropriated in ways that extend far beyond their original intended purpose. We identify how the currently available technology can be misused, discuss how pairing physiological data with non-physiological data can radically expand the predictive capacity of physiological wearables, and explore the implications of these expanded capacities for a variety of stakeholders.
title: Impacts of Policy and Design Events on the Success of National Health Information System: A Boundary Object Perspective
Creators: name: Solangasenathirajan, Sanjayan
Publisher: name: University of Reading
Year: 2023

description: Information Systems adoption is an area of focus for business change and transformation where innovative technologies and procedures provide perceived benefits to the organisation. However, the impact of Information Systems adoption, use and factors contributing to Information System success, alongside failures in a healthcare context is an area in need of further critical, empirical research. This study investigates the role and evolution of a health Information System in various organisational contexts to reveal the issues in adoption, the factors contributing to unintended use, and the impact of policy and design intention on Information System success. A longitudinal study was conducted into the human-information aspects in four cases within the National Health Service, to understand the changing sentiment towards a national health Information System in the context of emerging policy and design events. Analysis showed the importance of Information Systems adoptability, purposefulness and acceptance, and key barriers to adoption in the gap between clinical and administrative use versus intended use. Boundary work and effective feedback were identified as important components in addressing social aspects conveying policy and design intentions, and expectation setting in awareness practice across the interface between organisations, people, and Information System. User satisfaction emerged as a significant factor contributing to Information System success. Finally, an evaluation framework and conceptual model is proposed for the identification of factors contributing to Information System success. The findings from this study can be applied to socio-technical issues in the context of policy and design change in a national healthcare Information System, with the view of making continuous improvement leading to Information System adoption and success while simultaneously identifying and reducing factors that lead to failure.