cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Plasmacytoid dendritic cell activation and differentiation by the Human Immunodeficiency Virus type 1 and 2: Implications for HIV immunopathogenesis
Creators: name: Royle, Caroline
Publisher: name: Imperial College London
Year: 2014

description: Infection with HIV-1 results in the progressive dysfunction of the immune system eventually leading to AIDS, characterised by low CD4+ T lymphocyte counts and increased susceptibility to opportunistic infections. In contrast to HIV-1, individuals infected with HIV-2 often remain asymptomatic, with lower viral loads and higher CD4+ T cell counts throughout the course of disease. Furthermore, HIV-2+ individuals display enhanced HIV-specific T cell responses. In addition, HIV-1 disease progression is slower in patients with pre-existing HIV-2 infection. Plasmacytoid dendritic cells (pDCs) are key mediators of the early innate immune response. Upon viral infection, pDCs secrete high levels of type I IFN (IFN-α/β) which limit viral replication and prime the adaptive immune response. Activated pDCs, in particular excessive IFN-α/β, have been implicated in HIV-1 immunopathogenesis. Specifically pDCs may contribute to the recruitment of target cells to the site of HIV-1 infection, increased apoptosis of immune cells and suppression of memory T cell responses. The aim of this study was to compare the abilities of HIV-1 and HIV-2 to activate pDCs in vitro. HIV-1 was a more potent inducer of type I IFN responses in PBMCs compared to HIV-2, measured at both the transcriptional level, and by measuring IFN-α/β secretion into cell culture supernatants. Furthermore, HIV-2, but not HIV-1, inhibited IFN-α production in response to synthetic stimuli. Phenotypic analysis of pDCs by flow cytometry revealed that both HIV-1 and HIV-2 were equally able to induce an up-regulation of co-stimulatory marker expression. Measurement of co-stimulatory molecule expression in conjunction with IFN-α secretion showed that HIV-1 favoured an IFN response, whereas HIV-2 preferentially maturated pDCs towards an antigen-presenting cell (APC) phenotype. The ability of HIV-2 to mature pDCs into APCs while reducing IFN-α secretion may be an important contributor to more robust T cell responses and therefore slower progressing HIV disease.
Phryganea Linnaeus, 1758, gen. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Phryganeidae
Phryganea

description: Phryganea [gen. nov.]
Os edentulum: Palpis IV.
Antennae thorace longiores.
Alae incumbentes: inferioribus plicatis.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 547, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Diffuse Baryons in Groups and Clusters of Galaxies
Creators: name: Cavaliere, A.
name: Menci, N.
name: Tozzi, P.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: To predict the X-ray observables associated to the diffuse baryons in clusters of galaxies, we develop a new physical approach to model such a hot intra-cluster plasma. Such approach is based on punctuated equilibria. and comprises the following blocks: Monte Carlo ``merging histories'' of dark matter potential wells; the central hydrostatic disposition for the ICP, reset to a new equilibrium after each merging episode; conditions of shock, or of closely adiabatic compression at the boundary with the external gas, preheated by stellar energy feedbacks. We predict the L-T relation, consistent with the data as for shape and scatter. This we combine with the mass distribution provided by the hierarchical clustering for different COBE-normalized CDM models, to predict the z-resolved luminosity functions, the source counts, the redshift distributions and contribution of the unresolved groups and clusters to the soft X-ray background. When compared with the recent ROSAT surveys, our results confirm that the critical cosmology with Standard CDM is ruled out by its overproduction of local clusters. On account of underproduction, instead, we rule out open cosmologies except for a narrow range around Ω_o=0.5; even there, we find the consistency with the full data base to be hardly marginal. For Ω_o=0.3 in flat geometry, we obtain acceptable fits. For the tilted CDM perturbation spectrum with high baryonic content in the critical universe, we obtain marginal consistency. Finally, we discuss the effective limitations of X-ray clusters and groups as cosmological signposts, and their brighter prospects toward the astrophysics of the ICP and the cosmogony of large, high-contrast structures.
description: 19 Latex pages, 12 Postscript figures. Submitted to Astrophys. Journ. Part 1; added typos and references
Process development for forging lightweight multi-material gears
Creators: name: Politis, Denis
Publisher: name: Imperial College London
Year: 2013

description: The work presented in this thesis discusses the development of an innovative method for manufacturing tailored gears, specifically bi-metallic lightweight gears through the use of the forging process. Utilising this method, gears can be constructed from multiple metals, where high strength, high density materials are located in regions of high stress concentration, such as the tooth flank, tooth root and regions in contact with shaft attachment mechanisms. On the other hand, lower strength, lower density materials can be located at less critical regions, such as the central region of the gear, hence reducing weight. A patent has been filed for the production process of forging multi-material lightweight gears. To investigate this process, bi-metallic gear construction was studied, where a high strength outer ring; and low strength cylindrical or annular core placed within the confines of the ring, allowed for the production of high strength teeth. Experimental and simulation work was conducted to better understand the material flow which occurs during the forging process, and hence its implications on the structural integrity of the gear. To allow for experimental trials, a tool set was designed and manufactured, and used in conjunction with a forming press to forge gears of a spur gear profile. Gears were produced under both cold and hot forging conditions using model materials (lead and copper) and engineering alloys (aluminium and mild steel) respectively. This construction was evaluated for a range of ring thicknesses. A simplified Finite Element (FE) model was established to analyse the material flow and ring thickness distribution during the cold forging operation. Data for the materials commercially pure lead, copper (C101), aluminium alloy (Al 6082), mild steel (230M07) and gear steel (16MnCr5) were obtained through compressive experiments undertaken on Instron and Gleeble testing machines. Constitutive equations were calibrated to a unified constitutive equation model incorporating the physical parameters of stress, plastic strain rate, isotropic hardening, and dislocation density to model the behaviour of aluminium alloy, mild steel and gear steel allowing for the creation of a FE model representing the hot forging process. Furthermore, three locking mechanisms between the two materials were examined: macro-mechanical locking, micro-mechanical locking and diffusion bonding; which when coupled together may prevent disengaging during operation. In addition, the root and contact stresses experienced by bi-metallic gears were also compared to a single material steel gear through an FE model to identify performance differences. Finally, recommendations and future research directions are presented.
On Zero-Inflated Alternative Hyper-Poisson Distribution
Creators: name: Kumar, Satheesh
name: Ramachandran, Rakhi
Publisher: name: Statistica
Year: 2022

description: Here we develop a zero-inflated version of the alternative hyper-Poisson distribution and discuss its important statistical properties such as probability generating function, expressions for mean, variance, factorial moments, skewness, kurtosis, recursion formula for probabilities, raw moments and factorial moments. Then the maximum likelihood estimation of the parameters of the zero-inflated alternative hyper-Poisson distribution is discussed and certain test procedures are constructed for testing the significance of the inflation parameter. All the procedures are illustrated with the help of certain real life data sets. Moreover, a brief simulation study is carried out for assessing the performances
description: Statistica, Vol. 81 No. 4 (2021)
title: ADCO, Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Cart. 180 (11 H 755), 83 folios, f. 0103
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 180 (11 H 755), 83 folios, f. 0103, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 180 (11 H 755), 83 folios, f. 0103, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Solving The N-Body Problem in (2+1)-Gravity
Creators: name: Bellini, A.
name: Ciafaloni, M.
name: Valtancoli, P.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We construct a non-perturbative, single-valued solution for the metric and the motion of $N$ interacting particles in $2+1$-Gravity. The solution is explicit for two particles with any speed and for any number of particles with small speed. It is based on a mapping from multivalued Minkowskian coordinates to single-valued ones, which solves the non-abelian monodromies due to particles' momenta. The two and three-body cases are treated in detail.
description: 43 pages, LaTeX, ( figures are not included )
Anhelita Jordan 1895
Creators: name: Trýzna, Miloš
name: Baňař, Petr
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Anthribidae
Anhelita

description: Anhelita Jordan, 1895
(Figs 1–28)
Anhelita Jordan, 1895: 142. Bovie 1906: 235 (catalogue); Wolfrum 1929: 22 (catalogue); Alonso-Zarazaga & Lyal 1999: 34 (catalogue of world genera); Rheinheimer 2004: 24 (catalogue), 216 (fig. 53– Anhelita lineata Jordan, 1895, habitus in dorsal view [incorrectly stated as Anhelita cf. aphanes].
Type species: Anhelita lineata Jordan, 1895 (by original designation), type locality: Madagascar, Antananarivo Terminalia. See under Anhelita lineata.
Distribution of Anhelita. Genus is endemic to Madagascar.
description: Published as part of Trýzna, Miloš & Baňař, Petr, 2025, Taxonomic and nomenclatural changes in Malagasy species of Anhelita Jordan, Lemurisintor Frieser and Sintor Schoenherr (Anthribidae: Coleoptera), pp. 301-325 in Zootaxa 5621 (3) on page 303, DOI: 10.11646/zootaxa.5621.3.1, http://zenodo.org/record/15262745
Identification and characterisation of HLA-DRB1*0101 restricted CD4+ T cell epitopes in the major grass pollen allergens Phl p 1 and Phl p 5
Creators: name: Raynsford, Eleanor Jane
Publisher: name: Imperial College London
Year: 2011

description: Over 10 million people in the UK suffer from allergic rhinitis. The majority have symptoms caused by grass pollen exposure. Phl p 1 and Phl p 5 are the major grass pollen allergens in Timothy grass (Phleum pratense). Specific grass pollen immunotherapy using whole extract is an effective disease-modifying treatment, but it is associated with severe, life-threatening systemic IgE-mediated side-effects. One strategy to improve safety and clinical efficacy is to develop peptide immunotherapy for grass pollen allergy. The aim of this thesis was to identify HLA-DR1-restricted CD4+ T cell epitopes of Phl p 1 and Phl p 5 by complementary approaches of epitope mapping: in silico prediction, tetramer guided epitope mapping and human HLA-DR1 transgenics. I investigated recognition of HLA-DR1-restricted CD4+ T cell epitopes in allergic and non-allergic individuals and characterised epitope-specific CD4+ T cells, according to cell surface markers and cytokine production. HLA-DR1 transgenics were primed with either Phl p 1 or Phl p 5b protein and the T cell lines generated were screened using a panel of overlapping peptides in 3H-thymidine incorporation assays. HLA-DR1-tetramers loaded with Phl p 1 or Phl p 5b peptides were used in tetramer guided epitope mapping studies using PBMC from HLA-DR1+, grass-allergic, seasonal allergic rhinitis patients. Tetramer-positive populations were detectable in PBMC of >75% of patients studied. Epitope-specific CD4+ T cells were detectable immediately ex vivo in allergic and non-allergic individuals. Data suggest that epitope-specific CD4+ T cells from allergic individuals exhibit an effector memory, Th2-like phenotype. This study identified HLA-DR1-restricted CD4+ T cell epitopes for Phl p 1 and Phl p 5b and characterised epitope-specific CD4+ T cell responses. The epitopes identified may be used in peptide-based vaccines for grass pollen immunotherapy.
Additional file 1 of Clinical and cytokine patterns of uncontrolled asthma with and without comorbid chronic rhinosinusitis: a cross-sectional study
Creators: name: Huang, Kai
name: Li, Fangyuan
name: Wang, Xuechen
name: Yan, Bing
name: Wang, Ming
name: Li, Shuling
name: Yu, Wenling
name: Liu, Xiaofang
name: Wang, Chengshuo
name: Jin, Jianmin
name: Zhang, Luo
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Additional file 1. Figure S1: Comparison of characteristics associated with comorbid rhinosinusitis within the 3 clusters.
Oral history interview with Miriam McCreary , 2002
Publisher: name: Columbia University
Year: 2019
Subjects: Obstetricians
Gynecologists
Abortion--United States
Abortion services--Minnesota
Reproductive rights--United States

description: Physician at Regions Hospital in St. Paul; experiences providing abortions in Minnesota, Sioux Falls, and Fargo; difficulties finding providers to perform elective abortions for clinics in these areas; concerns over who will provide abortions after her retirement; fear for her own safety as abortion provider
MOESM1 of Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance
Creators: name: Toonen, Erik
name: Andreea-Manuela Mirea
name: Tack, Cees
name: Stienstra, Rinke
name: Ballak, Dov
name: Diepen, Janna
name: Hijmans, Anneke
name: Chavakis, Triantafyllos
name: Dokter, Wim
name: Pham, Christine
name: Netea, Mihai
name: Dinarello, Charles
name: Joosten, Leo
Publisher: name: figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 60506 Virology
subject: Computational Biology

description: Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance
The Stellar Populations of Pixels and Frames
Creators: name: Renzini, Alvio
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Derived from first physical principles, a few simple rules are presented that can help in both the planning and interpretation of CCD and IR-array camera observations of resolvable stellar populations. These rules concern the overall size of the population sampled by a frame as measured by its total luminosity, and allow to estimate the number of stars (in all evolutionary stages) that are included in the frame. The total luminosity sampled by each pixel (or resolution element) allows instead to estimate to which depth meaningful stellar photometry can be safely attempted, and below which crowding makes it impossible. Simple relations give also the number of pixels (resolution elements) in the frame that will contain an unresolved blend of two stars of any kind. It is shown that the number of such blends increases quadratically with both the surface brightness of the target, as well as with the angular size of the pixel (or resolution element). A series of examples are presented illustrating how the rules are practically used in concrete observational situations. Application of these tools to existing photometric data for the inner parts of the bulge of M31, M32 and NGC 147 indicates that no solid evidence has yet emerged for the presence of a significant intermediate age population in these objects.
description: 28 pages, LaTeX file using aasms4.sty, 2 postscript figures To appear on: The Astronomical Journal
Developmental regulation of cohesin positioning on mammalian chromosome arms
Creators: name: Mira Bontenbal, Hegias
Publisher: name: Imperial College London
Year: 2011

description: Cohesin has a well-­established role in sister chromatid cohesion and postreplicative DNA repair. In addition, previous work in our laboratory suggested a positive correlation between cohesin binding and gene expression (Parelho et al. 2008). We decided to establish the ChIP-­seq technique to address the relationship between cohesin binding and gene expression at the genome-­wide level. However, in the meantime, several other groups reported genome-­wide binding maps of cohesin in embryonic stem (ES) cells, demonstrating cell-­type-­specific cohesin binding and its correlation with gene expression (Schmidt et al. 2010; Kagey et al. 2010; Nitzsche et al. 2011). Kagey and colleagues argue that cohesin is required for the expression of pluripotency-­associated genes, based on cohesin downregulation for an extended time period. We believe this method generates indirect effects such as cell stress, death and enrichment for slowly cycling differentiating cells, biasing the results towards differentiated cells. We have generated ES cells homozygous for conditional Rad21 alleles and have found that, unlike the Kagey approach, rapid 24-­hour cohesin depletion does not induce cell stress responses. We detect a stronger correlation between cohesin-­bound genes and gene expression changes, suggesting our approach is more accurate in understanding the role of cohesin in gene expression. We have expanded our analysis of cohesin binding by generating ES cells expressing epitope-­tagged BORIS, a paralogue of CTCF. We have mapped BORIS binding sites in ES cells and data suggest that BORIS, unlike CTCF, does not recruit cohesin. To study the specific involvement of cohesin in gene expression, two developmentally regulated models, T cell receptor α (Tcrα) rearrangement and X chromosome inactivation (XCI), have been used. Cohesin loss in non-­cycling developing thymocytes leads to impaired Tcrα rearrangement. Finally, we present evidence that cohesin contributes to creating chromatin boundaries that segregate facultative heterochromatin from active chromatin on the inactive X chromosome in differentiating female ES cells.
Critical factors and enablers of food quality and safety compliance risk management in the Vietnamese seafood supply chain
Creators: name: Tran, Thi Huong
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Finance (q-fin.GN)
subject: FOS: Economics and business

description: Recently, along with the emergence of food scandals, food supply chains have to face with ever-increasing pressure from compliance with food quality and safety regulations and standards. This paper aims to explore critical factors of compliance risk in food supply chain with an illustrated case in Vietnamese seafood industry. To this end, this study takes advantage of both primary and secondary data sources through a comprehensive literature research of industrial and scientific papers, combined with expert interview. Findings showed that there are three main critical factor groups influencing on compliance risk including challenges originating from Vietnamese food supply chain itself, characteristics of regulation and standards, and business environment. Furthermore, author proposed enablers to eliminate compliance risks to food supply chain managers as well as recommendations to government and other influencers and supporters.
Condition Monitoring and Optical Strain Measurement for Power Industry Components
Creators: name: Palmer, Iain Alastair
Publisher: name: Imperial College London
Year: 2011

description: Condition monitoring and life extension of components is vital to reducing risk of failure and operational costs in the power industry. Optical strain measurement techniques have been studied and developed for use in condition monitoring of power plant steam pipes and wind turbine components. In addition, these techniques have been used to assist evaluation of damage mechanisms in these components. Power plant steam pipes operate at high temperature (approximately 600°C) and pressure, and as a result undergo large creep deformations. Monitoring creep strain is a key factor in assessing remaining life of important components. An optical strain measurement system developed by EON, Automatic Reference Creep Measurement And Control (ARCMAC) has been researched as to its combined effectiveness with Digital Image Correlation (DIC) in obtaining accurate and reliable strain measurement for high temperature components. DIC has also been used to monitor and evaluate damage in composite wind turbine blade components. The use of this optical strain technique has allowed comparison of experimentally-derived full-field strain maps to be compared with finite element analysis (FEA) results. Additionally, the use of acoustic emission (AE) as a condition monitoring technique for wind turbine blades has been investigated. Use of these techniques has given greater understanding of failure mechanisms in wind turbine components; in particular, transverse tensile damage and delamination have been investigated. The influence of the Brazier effect upon wind turbine blade failure has also been researched. Results of this research have evaluated accuracy of using optical strain measurement techniques as well as their ability to effectively measure strain in particular regions of interest. The application of such techniques is an important requirement for both power plant and wind turbine components. Finally, studies into the use of optical strain measurement techniques as lab-based tools to study failure mechanisms have been performed.
Phryganea grandis Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Phryganeidae
Phryganea
Phryganea grandis

description: Phryganea grandis [spec. nov.]
P. alis cinereo testaceis: lineolis duabus longitudinalibus nigris: puncto albo. Fn. svec. 740.
Reaum. ins. 3. t. 14. f. 4?
Roes. aqu. 2. t. 17.
Habitat in Europa, intra cylindrum ex ramentis longitudinalibus ligneis.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 548, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
The Other Spectral Flow
Creators: name: Gato-Rivera, Beatriz
name: Rosado, Jose Ignacio
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Recently we showed that the spectral flow acting on the N=2 twisted topological theories gives rise to a topological algebra automorphism. Here we point out that the untwisting of that automorphism leads to a spectral flow on the untwisted N=2 superconformal algebra which is different from the usual one. This "other" spectral flow does not interpolate between the chiral ring and the antichiral ring. In particular, it maps the chiral ring into the chiral ring and the antichiral ring into the antichiral ring. We discuss the similarities and differences between both spectral flows. We also analyze their action on null states.
description: Latex, 7 pages
Influence of Succinimide Dispersants on Film Formation, Friction and Antiwear Properties of Zinc Dialkyl Dithiophosphate
Creators: name: Zhang, Jie
Publisher: name: Imperial College London
Year: 2010

description: ZDDP (zinc dialkyldithiophosphate) is arguably the most successful antiwear additive ever employed in crankcase engine lubricants. It was originally used as an antioxidant and shortly afterwards recognized for its antiwear and extreme pressure properties. Unfortunately, another critical additive polyisobutylsuccinimide-polyamine (PIBSA-PAM), which is used as a dispersant in engine oils, is known to be antagonistic to ZDDP in terms of film formation, friction and wear. The mechanisms of this antagonism have been widely studied, but they are still not well understood. Furthermore, in order to protect engine exhaust catalysts from sulphated ash, phosphorus and sulphur (SAPS) and extend drain intervals of engine lubricants, a progressive reduction in ZDDP quantity but a growth in the use of PIBSA-PAM is required. The aim of this study is to explore the mechanisms and practical effects of the antagonism between ZDDP and PIBSA-PAM. Of particular interest is the impact on performance of the ratio of ZDDP to PIBSA-PAM, as measured by P:N ratio. Since ZDDP is a very effective antiwear additive, it produces only very low or "mild" rates of wear. To study this requires a new way to measure mild wear behaviour of formulated oils. Several techniques have been applied in this study to investigate the film formation, friction and wear properties of ZDDP- and/or PIBSA-PAM-containing oils. These include a new mild wear testing method, which is tested and developed using a range of different types of additives. It is found that the ratio of P:N plays a strong role in determining tribofilm formation and friction of ZDDP/PIBSA-PAM blends. However it plays a much weaker role in determining wear behaviour. It is found that some PIBSA-PAMs have considerable friction-reducing properties in their own right. The results suggest that PIBSA-PAM may interfere with the behaviour of ZDDP in several ways: by forming a ZDDP/ PIBSA-PAM complex at the metal surfaces to reduce the local activity of ZDDP; by PIBSA-PAM partially removing the ZDDP film; possibly also by PIBSA-PAM blocking ZDDP from metal surfaces. The newly-developed wear testing method can be used conveniently and effectively to study mild wear properties not just of ZDDP but of a wide range of other additives.
Towards the Total Synthesis of Anthraquinone Antifungal Agents Sch 47554 and Sch 47555
Creators: name: Espensen, George Max
Publisher: name: Imperial College London
Year: 2011

description: The total synthesis of Sch 47554 (1) is the focus of this project, with the intention of using two aryne-furan cycloaddition reactions to efficiently build the anthraquinone core of the molecule. The first is intermolecular with furan, which is then elaborated with a C-aryl glycosidation reaction. The second is intramolecular between 5 and 6 where the two fragments are linked by a disposable tether connected through the oxygen functionalities, as demonstrated in 2. This ensures the correct angularly-fused regiochemistry of the aryne-furan cycloaddition. [Molecular structure diagrams appear here. To view, please open pdf attachment]. To this end suitable precursors have been examined. After several unsuccessful attempts at making various suitably-functionalised precursors, double aryne precursor 8 was synthesised and converted into naphthol 10. This was successfully glycosylated, but this substrate is less flexible later in the synthesis than another substrate developed, 9. This was converted into naphthol 10 and the glycosidation is currently being optimised. Elsewhere in the group furan 6 has been synthesised. These systems are appropriate for completing the synthesis of 1. [Molecular structure diagrams appear here. To view, please open pdf attachment].
Generalised Born-Infeld models, Lax operators and the $\textrm{T} \bar{\textrm{T}}$ perturbation
Creators: name: Conti, Riccardo
name: Iannella, Leonardo
name: Negro, Stefano
name: Tateo, Roberto
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Surprising links between the deformation of 2D quantum field theories induced by the composite $\textrm{T} \bar{\textrm{T}}$ operator, effective string models and the $AdS/$CFT correspondence, have recently emerged. The purpose of this article is to discuss various classical aspects related to the deformation of 2D interacting field theories. Special attention is given to the sin(h)-Gordon model, for which we were able to construct the $\textrm{T} \bar{\textrm{T}}$-deformed Lax pair. We consider the Lax pair formulation to be the first essential step toward a more satisfactory geometrical interpretation of this deformation within the integrable model framework. Furthermore, it is shown that the 4D Maxwell-Born-Infeld theory, possibly with the addition of a mass term or a derivative-independent potential, corresponds to a natural extension of the 2D examples. Finally, we briefly comment on 2D Yang-Mills theory and propose a modification of the heat kernel, for a generic surface with genus $p$ and $n$ boundaries, which fully accounts for the $\textrm{T} \bar{\textrm{T}}$ contribution.
description: 22 pages, 2 figures, v2: new comments, hyperlinks and minor typos corrected
Cubic couplings in D=6 N=4b supergravity on AdS_3\times S^3
Creators: name: Arutyunov, G.
name: Pankiewicz, A.
name: Theisen, S.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We determine the AdS exchange diagrams needed for the computation of 4--point functions of chiral primary operators in the SCFT_2 dual to the D=6 N=4b supergravity on the AdS_3\times S^3 background and compute the corresponding cubic couplings. We also address the issue of consistent truncation.
description: 30 pages, 4 figures, LaTeX, uses feynman and pictex
Investigation of the role of thyroid hormone receptor beta in the ventromedial nucleus of the hyptholamus in the mediation of energy homeostasis
Creators: name: Hameed, Saira
Publisher: name: Imperial College London
Year: 2011

description: The hypothalamus is a region of the central nervous system that is important in the regulation energy homeostasis. Thyroid hormone action within the hypothalamus has been shown to influence food intake and body weight and these effects may be mediated through the nuclear transcription factor thyroid hormone receptor beta (TRβ), which is highly expressed within the ventromedial nucleus (VMN) of the hypothalamus. Recombinant adeno-associated virus (rAAV) expressing Cre recombinase (rAAV-Cre) was synthesised. This was injected bilaterally into the VMN of adult mice which were bred for locus of crossover of phage P1 (LoxP) sites within the THRB gene TRβflox/flox) which encodes TRβ . Cre recombination in these mice introduces a frame shift, so that only truncated products are encoded. This results in TRβ knock down in the VMN. Recombinant AAV encoding green fluorescent protein (GFP) (rAAV-GFP) was injected bilaterally into the VMN of control mice. Cre mediated tissue specific knockdown of TRβ in the VMN resulted in a highly significant increase in body weight over sixty three days. The cumulative food intake over the course of the study was significantly greater in mice with TRβ knock down in the VMN compared with controls. Furthermore, mice with intra-VMN TRβ knock down mice failed to become obese when pair-fed to the food intake of control animals, but when allowed to ad libitum feed once again, gained significantly more weight and ate significantly more than controls. The importance of hyperphagia to the obese phenotype was further underscored by the level of uncoupling protein-1 mRNA in brown adipose tissue which was unaltered in intra-VMN TRβ knock down mice. This work is the first to show the essential function of TRβ in the VMN in the regulation of food intake and body weight by demonstrating that TRβ knock down in the VMN results in hyperphagia and obesity.
Design, Control, and Harmonic Compensation for Stand-Alone and Grid-Connected Voltage-Source Converters: Simulation and Experimental Validations
Creators: name: Nazeri, Ahmad Ali
Publisher: name: Universität Kassel
Year: 2024
Subjects: subject: Current Control
subject: Voltage Control
subject: Proportional-Resonant Controller
subject: Repetitive Control
subject: Discretization
subject: Multi-Resonant control
subject: Droop controller
subject: Total Harmonic Distortion
subject: Stand-Alone Voltage Source Inverter
subject: Grid-Connected Voltage Source Converter
subject: Microgrid
subject: 004
subject: 600
subject: Stromregelung
subject: Spannungsregelung
subject: Microgrid
subject: Diskretisierung

description: Zugleich: Dissertation, Universität Kassel, 2023
Clues to Outflows: Polarization of IRAS-Selected QSOs
Creators: name: Wills, Beverley J.
name: Hines, Dean C.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Broad-band polarimetry and spectropolarimetry of a complete sample of 18 luminous AGNs (Lbol > 10^11.5 Lsun), selected in an orientation-independent way by warm infrared flux, shows that an orientation-dust-covering Unified Scheme like that successfully explored for the lower luminosity Seyfert galaxies applies to the luminous QSOs. Broad emission lines and continuum seen in polarized (scattered) light show that hyperluminous infrared galaxies contain buried QSO nuclei and are therefore the `missing' QSO 2s -- the high-luminosity analogs of Seyfert 2 galaxies like NGC1068. Most of the QSOs show significant polarization and reddening. Three are `classical' low-ionization BALQSOs, and several others have narrower, blueshifted, low-ionization absorption. These properties are to be compared with those of the UV-optically selected QSOs, of which only ~1% show low-ionization BALs, and only the BALQSOs show significant polarization. Outflows are therefore much more common than previously suspected.
description: 7 pages latex, paspconf,epsf, includes 3 figures
Hemerobius perla Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Chrysopidae
Hemerobius
Hemerobius perla

description: Hemerobius perla [spec. nov.]
H. viridis, alis hyalinis: vasis viridibus. Faun. svec. 731.
Mouff. ins. 937. Musca chrysops.
Goed. ins. 2. p. 40. t. 14.
Alb. ins. t. 64.
Merian. eur. 3. p. 49. t. 8.
Vallisn. nat. 1. p. 77. t. 2.
Pet. mus. 4. n. 6. Perla merdam olens.
Raj. ins. 274. Musca quadripennis, corpore luteo viridi.
Reaum. ins. 3. t. 33. f. 2. 5. 6. Leo Aphidum.
Roes. ins. 3. p. 127. t. 21. f. 4, 5.
Habitat in Europae plantis, victitans Aphidibus.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 549, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
All order I.R. finite expansion for short distance behavior of massless theories perturbed by a relevant operator
Creators: name: Guida, R.
name: Magnoli, N.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider here renormalizable theories without relevant couplings and present an I.R. consistent technique to study corrections to short distance behavior (Wilson O.P.E. coefficients) due to a relevant perturbation. Our method is the result of a complete reformulation of recent works on the field, and is characterized by a more orthodox treatment of U.V. divergences that allows for simpler formulae and consequently an explicit all order (regularization invariant) I.R. finitess proof. Underlying hypotheses are discussed in detail and found to be satisfied in conformal theories that constitute a natural field of application of this approach.
description: 27 pages
Oral history interview with Mitchell S. Rosenthal, 1981
Publisher: name: Columbia University
Year: 2020
Subjects: Drug addicts--United States
Drug abuse--History--20th century.--United States
Drug addicts--Rehabilitation--United States
Therapeutic communities
Methadone maintenance--History--20th century.--United States

description: In this interview, Mitchell Rosenthal discusses his life and career, primarily his founding of a residential drug rehabilitation program, Phoenix House, in 1967. Rosenthal explains how he was exposed to the Synanon treatment model while serving in the navy in the mid-1960s, and how it inspired him to make structural changes at the Oak Knoll Naval Hospital in Oakland, California while he served there as the staff psychiatrist. He discusses the founding of Phoenix House, and the economic conditions that facilitated the program's rapid expansion. He breaks down the budget of Phoenix House, and explains how the organization is funded. Rosenthal discusses trends in the demographics of patients, in terms of age, education level, and types of drugs used. He compares the methadone maintenance model to the therapeutic community model, and discusses popular criticisms of the therapeutic community model. He also compares Phoenix House to its peer facilities, such as Synanon, Daytop, and Odyssey House. Rosenthal describes his hopes for the future of therapeutic communities
Stochastic Modeling and Inference of Large-scale Gene Regulatory Networks
Creators: name: Kim, Haseong
Publisher: name: Imperial College London
Year: 2012

description: Gene regulatory networks (GRNs) consist of thousands of genes and proteins which are dynamically interacting with each other. Researchers have investigated how to uncover these unknown interactions by observing expressions of biological molecules with various statistical/mathematical methods. Once these regulatory structures are revealed, it is necessary to understand their dynamical behaviors since pathway activities could be changed by their given conditions. Therefore, both the regulatory structure estimation and dynamics modeling of GRNs are essential for biological research. Generally, GRN dynamics are usually investigated via stochastic models since molecular interactions are basically discrete and stochastic processes. However, this stochastic nature requires heavy simulation time to find the steady-state solution of the GRNs where thousands of genes are involved. This large number of genes also causes difficulties such as dimensionality problem in estimating their regulatory structure. This thesis mainly focuses on developing methodologies for large-scale GRN analyses. It includes applications of a stochastic process theory called G-networks and a reverse engineering technique for large-scale GRNs. Additionally a series of bioinformatics techniques was applied in brain tumor data to detect disease candidate genes along with their large-scale GRNs. The proposed techniques such as stochastic modeling (bottom-up) and reverse engineering (top-down) could provide a systematic view of a complex system and an efficient guideline to identify candidate genes or pathways triggering a specific phenotype of a cell. As further work, the combinatorial use of the modeling and reverse engineering approaches would be helpful in obtaining a reliable mathematical model and even in developing a synthetic biological system.
title: ADCO, Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Cart. 29 (G 134), 996 folios, f. 0408
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi

description: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0408, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0408, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Additional file 1: of Public awareness and individual responsibility needed for judicious use of antibiotics: a qualitative study of public beliefs and perceptions
Creators: name: Ancillotti, Mirko
name: Eriksson, Stefan
name: Veldwijk, Jorien
name: Fahlquist, Jessica NihlĂŠn
name: Andersson, Dan
name: Godskesen, Tove
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy

description: Interview guide. Structure and contents (questions and probes) of the interview guide. (DOCX 20 kb)
A Note on the Weyl Anomaly in the Holographic Renormalization Group
Creators: name: Fukuma, Masafumi
name: Matsuura, So
name: Sakai, Tadakatsu
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We give a prescription for calculating the holographic Weyl anomaly in arbitrary dimension within the framework based on the Hamilton-Jacobi equation proposed by de Boer, Verlinde and Verlinde. A few sample calculations are made and shown to reproduce the results that are obtained to this time with a different method. We further discuss continuum limits, and argue that the holographic renormalization group may describe the renormalized trajectory in the parameter space. We also clarify the relationship of the present formalism to the analysis carried out by Henningson and Skenderis.
description: LaTeX, 24 pages, 2 figures, typos corrected
Amnestic Forgery: an Ontology of Conceptual Metaphors
Creators: name: Gangemi, Aldo
name: Alam, Mehwish
name: Presutti, Valentina
Publisher: name: arXiv
Year: 2018
Subjects: subject: Computation and Language (cs.CL)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: This paper presents Amnestic Forgery, an ontology for metaphor semantics, based on MetaNet, which is inspired by the theory of Conceptual Metaphor. Amnestic Forgery reuses and extends the Framester schema, as an ideal ontology design framework to deal with both semiotic and referential aspects of frames, roles, mappings, and eventually blending. The description of the resource is supplied by a discussion of its applications, with examples taken from metaphor generation, and the referential problems of metaphoric mappings. Both schema and data are available from the Framester SPARQL endpoint.
Oral history interview with Moe Howard, 1958
Publisher: name: Columbia University
Year: 2020
Subjects: Motion picture actors and actresses--United States
Actors
Motion picture industry--History--20th century.--United States
Motion pictures--History--20th century.--United States
Popular culture--History--20th century.--United States

description: Audio is comprised of narrator's excerpts from the Westinghouse Broadcasting Company's radio program series "Memoirs of the Movies"
title: ADCO, Cart. 186 (11 H 71), f. 0030v
Creators: name: de la Côte d'Or, Archives départementales
name: CBMA/CG21/F.PETOT/2012
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la Côte-d'Or, C
art. 186 (11 H 71). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la
 Côte-d'Or, Cart. 186 (11 H 71), f. 0030v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-
project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
$J\bar{T}$ deformed $CFT_2$ and String Theory
Creators: name: Chakraborty, Soumangsu
name: Giveon, Amit
name: Kutasov, David
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study two dimensional conformal field theory with a left-moving conserved current $J$, perturbed by an irrelevant, Lorentz symmetry breaking operator with the quantum numbers of $J\bar{T}$, using a combination of field and string theoretic techniques. We show that the spectrum of the theory has some interesting features, which may shed light on systems of interest for holography and black hole physics.
description: 38 pages, references added