cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Lunaferamita virginiensis Utgaard 1981
Creators: name: Ernst, Andrej
name: Carrera, Marcelo G.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Bryozoa
Stenolaemata
Cystoporida
Constellariidae
Lunaferamita
Lunaferamita virginiensis

description: Lunaferamita virginiensis Utgaard, 1981
(Fig. 4 A-E; Appendix 1)
Lunaferamita virginiensis Utgaard, 1981: 1068-1070, pl. 3, figs 1-9.
MATERIAL EXAMINED.— CEGH-UNC27506 a,b, CEGH-UNC27507 c, CEGH-UNC 27513 a-d, CEGH-UNC 27516c, CEGH-UNC 27520a,b, CEGH-UNC 27524 a,b, CEGH-UNC 27533 b, CEGH-UNC 27538 b.
OCCURRENCE. — La Pola Formation, Upper Ordovician, Sandbian; La Pola creek section near Albardon village, San Juan Province, Argentine Precordillera, western Argentina.
DESCRIPTION
Massive, encrusting, partly multilayered, or subramose colonies. Massive colony up to 20 mm in height, subramose extensions 3.8-5.0 mm in diameter. Autozooecia growing from thin epitheca, bending in the early exozone to the colony surface. Epitheca 0.003 -0.005 mm thick. Basal diaphragms abundant, straight or inclined, thin. Macrozooecia surrounding maculae, 0.14-0.22 mm wide. Autozooecial apertures circular to oval. Lunaria well-developed, rounded to slightly triangular,consisting of granular material; ends of lunaria not indenting autozooecia. Vesicles small to large, not completely separating autozooecia, arranged in 1-2 rows between apertures, 4-8 surrounding each autozooecial aperture, with rounded to flat roofs, polygonal in tangential section.Autozooecial walls granular prismatic, 0.005 - 0.020 mm thick. Colony surface covered by laminated stereom. Acanthostyles in stereom present, 0.015 -0.030 mm in diameter, more abundant in maculae.Maculae consisting of vesicular skeleton with larger vesicles,surrounded by macrozooecia, 0.67-1.25 mm in diameter, spaced 1.13-1.75 mm from centre to centre.
COMPARISON
Lunaferamita virginiensis Utgaard, 1981 differs from L. bassleri (Loeblich, 1942) by having smaller autozooecia, less abundant acanthostyles and more abundant diaphragms. Lunaferamita virginiensis differs from L. vesicularis Chang, Yang & Xigiang, 2011 by having encrusting and massive colonies instead of ramose ones in the latter species.
description: Published as part of Ernst, Andrej & Carrera, Marcelo G., 2022, A cool-water bryozoan association from the La Pola Formation (Sandbian, Ordovician) of Argentine Precordillera, pp. 563-601 in Geodiversitas 44 (20) on page 568, DOI: 10.5252/geodiversitas2022v44a20, http://zenodo.org/record/6725916
Self-Efficacy Experiences and Attitudes of Saudi Female English Language Learners in Australia Towards Learning with Technology Use
Creators: name: ALFAIDI, SAFAA HAMEED
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 390104
subject: English and literacy curriculum and pedagogy (excl. LOTE, ESL and TESOL)
classificationCode: 390108
subject: LOTE, ESL and TESOL curriculum and pedagogy

description: Saudi women who move to Western countries for postgraduate study cross physical, cultural and gender boundaries and are frequently faced with new and sometimes challenging practices with digital technology in education. Bandura’s (1997) Self Efficacy Experiences are used as a lens to help understand the students’ initial attitudes toward digital technology in education, and to examine the impact of Australian educational experiences on changing attitudes. This examination of cultural immersion on attitudes suggests that, in contrast to their initial attitudes, for Saudi women, the use of technology in education has become an important resource that allows for autonomous learning experiences.
Loxodontomys pikumche Spotorno, Cofre, Manriquez, Vilina, Marquet, and Walker 1998
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Loxodontomys
Loxodontomys pikumche

description: Loxodontomys pikumche Spotorno, Cofre, Manriquez, Vilina, Marquet, and Walker 1998
Loxodontomys pikumche Spotorno, Cofre, Manriquez, Vilina, Marquet, and Walker 1998, Rev. Chilena Hist. Nat., 71: 362.
Type Locality: Chile, Region Metropolitana, Cajón del Río Maipo, Cruz de Piedra, 55 km S de la Central Hidroelectrica de Las Melosas, 2450 m; 34º10′S, 69º58′W.
Vernacular Names: Pikumche Pericote.
Distribution: C Chile; limits unknown.
Discussion: Northern sister species to L. micropus and allopatric with it as so far known, the two differing in chromosomal and morphological traits (Spotorno et al., 1998).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1123, DOI: 10.5281/zenodo.7316535
title: En la dolencia, y convalescencia de nuestros inclytos monarcas don Carlos segundo, y Doña Maria-Ana de Neoburg. Recordaron Perico, y Marica de su sueño, al estruendo del susto, y hablaron despiertos, à impulsos de mejor alboroço. Romance
Creators: name: Anonyme
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: (8) p.
«Perico, y Marica, que...»
description: Source: Bibliothèque patrimoniale Villon (Rouen), fonds Degrave, Mt m 20581-7-AB
Lundomys Voss and Carleton 1993
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Lundomys

description: Lundomys Voss and Carleton 1993
Lundomys Voss and Carleton 1993, Am. Mus. Novit., 3085: 5.
Type Species: Hesperomys molitor Winge 1887
Species and subspecies: 1 species:
Species Lundomys molitor (Winge 1887)
Discussion: Oryzomyini. A tetralophodont form related to Holochilus, Noronhomys, and Pseudoryzomys (Carleton and Olson, 1999; Voss and Carleton, 1993; Weksler, 2003).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1124, DOI: 10.5281/zenodo.7316535
Urinary Hydroxyproline as an Inflammation-Independent Biomarker of Inflammatory Bowel Disease
Creators: name: Huss, Muriel
name: Elger, Tanja
name: Loibl, Johanna
name: Kandulski, Arne
name: Binder, Benedicta
name: Stoeckert, Petra
name: Mester, Patricia
name: Müller, Martina
name: Buechler, Christa
name: Tews, Hauke Christian
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: urine; calprotectin; primary sclerosing cholangitis; C-reactive protein; IBD; hydroxyproline
subject: 610 Medizin

description: Predicting responses and monitoring the severity of inflammatory bowel disease (IBD)
is challenging due to a lack of specific biomarkers. This study identifies urinary hydroxyproline,
a marker of collagen turnover elevated in experimental colitis, as independent of conventional
biomarkers like creatinine, glomerular filtration rate, C-reactive protein, and fecal calprotectin.
Among 71 IBD patients, urinary hydroxyproline levels were significantly higher compared with
36 controls, with an area under the receiver operating characteristic curve of 0.814, highlighting
its potential as a diagnostic tool. No significant difference in hydroxyproline levels was observed
between the 50 Crohn’s disease and 21 ulcerative colitis patients, nor was there a correlation with
kidney function markers, gastrointestinal symptom severity, or stool consistency. Disease localization
was not associated with urinary hydroxyproline levels. Interestingly, 14 patients with primary
sclerosing cholangitis and IBD also exhibited elevated urinary hydroxyproline levels, comparable to
IBD patients but higher than healthy controls. This underscores the role of urinary hydroxyproline as
an independent biomarker for IBD diagnosis, without association with disease severity or established
markers like fecal calprotectin.
title: Activité du port de Saint-Malo – 1708 – Pleumeur-Bodou
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: produits manufacturés

description: Cette fiche est issue de l’enquête menée par Jean Delumeau sur l’activité du port de Saint-Malo au 17e et 18e siècle. Cette fiche correspond à l’activité de l’année 1708 avec le port "Plemeur Bodou"
description: Marchandises arrivées à Saint-Malo : chanvre
description: Catégories de marchandises arrivées à Saint-Malo : produits manufacturés
description: Coverage: Petit cabotage
description: Bibliographic citation: LEPROHON, Roger. La Vie maritime à Saint-Malo en 1708. DES : Histoire : Rennes, 1962 (Bibliothèque François-Lebrun, MH 1015)
description: date: Date de numérisation : 2021 à 2023
description: created: Années 1950-1960
Lettre de Joseph Gaspard de Pailloux de Cascatel à Jean-François Séguier, 1770-09-04
Creators: name: Pailloux de Cascatel (de), Joseph Gaspard
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Minéralogie

description: "[transcription] Votre lettre vient de m’être renvoyée ici, Monsieur, ou je suis en qualité de commissaire du roi pour fixer les limites entre la comté de Foix et le pays d’Andorre et la vallée de Cavola. Je suis bien fâché de n’avoir pu faire ma cour à Mme la princesse de Jablononka. Elle m’a fait l’honneur de m’écrire et ne m’ayant point donné son adresse, je ne sais où lui répondre, c’est ce qui me détermine d’avoir l’honneur de vous adresser ma réponse pour cette princesse. J’ai deux morceaux qui sont de la plus [fol. 315v] grande beauté. L’un est un madrépore agatisé et pli qui serait digne de cette place dans le cabinet du roi et l’autre est un bloc de coquilles pétrifiées et cristallisées. Ce bloc peut avoir deux pans et demi de long sur un grand pan de large. Je troquerais volontiers les deux morceaux pour quelque bijou. Ces deux morceaux sont d’un prix considérable. Je serai toujours enchanté, Monsieur, de pouvoir conserver correspondance avec vous et je ferai tout le cas que méritent les personnes qui me seront adressées de votre part.
J’ai l’honneur d’être avec un attachement respectueux, Monsieur, votre très humble et très obéissant serviteur.

A Porté dans les Pyrénées le 4 septembre 1770.

Cascatel

Il faut s’il vous plait m’adresser votre réponse à [fol. 316] Narbonne parce que ma femme me la fera parvenir et pour éviter qu’on ne la renvoyât du bureau de Narbonne. Vous aurez la bonté de l’adresser sous enveloppe à Mme de Cascatel. Faites-moi l’amitié de me dire où je devrai adresser la caisse pour Mme la princesse de Barclaw."
description: Source: [établissement de conservation] Nîmes, Bibliothèque Carré d'Art Nîmes, Bibliothèque Carré d'Art [cote]ms. 94, fol. 315-316
description: Coverage: [lieu d'expédition] Porté (France) | [lieu de destination] Nîmes (France)
Cytokine Response of Natural Killer Cells to Hepatitis B Virus Infection Depends on Monocyte Co-Stimulation
Creators: name: Kupke, Paul
name: Brucker, Johanna
name: Wettengel, Jochen M.
name: Protzer, Ulrike
name: Wenzel, Jürgen J.
name: Schlitt, Hans J.
name: Geissler, Edward K.
name: Werner, Jens M.
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: hepatitis B virus; HBV; natural killer cells; NK cells; monocytes; bystander activation; HepG2; HepaRG; NTCP
subject: 610 Medizin

description: Hepatitis B virus (HBV) is a major driver of chronic hepatic inflammation, which regularly leads to liver cirrhosis or hepatocellular carcinoma. Immediate innate immune cell response is crucial for the rapid clearance of the infection. Here, natural killer (NK) cells play a pivotal role in direct cytotoxicity and the secretion of antiviral cytokines as well as regulatory function. The aim of this study was to further elucidate NK cell responses triggered by an HBV infection. Therefore, we optimized HBV in vitro models that reliably stimulate NK cells using hepatocyte-like HepG2 cells expressing the Na+-taurocholate co-transporting polypeptide (NTCP) and HepaRG cells. Immune cells were acquired from healthy platelet donors. Initially, HepG2-NTCP cells demonstrated higher viral replication compared to HepaRG cells. Co-cultures with immune cells revealed increased production of interferon-γ and tumor necrosis factor-α by NK cells, which was no longer evident in isolated NK cells. Likewise, the depletion of monocytes and spatial separation from target cells led to the absence of the antiviral cytokine production of NK cells. Eventually, the combined co-culture of isolated NK cells and monocytes led to a sufficient cytokine response of NK cells, which was also apparent when communication between the two immune cell subpopulations was restricted to soluble factors. In summary, our study demonstrates antiviral cytokine production by NK cells in response to HBV+ HepG2-NTCP cells, which is dependent on monocyte bystander activation.
Serum Adiponectin Predicts COVID-19 Severity
Creators: name: Pavel, Vlad
name: Räth, Ulrich
name: Schmid, Stephan
name: Krautbauer, Sabrina
name: Keller, Dennis
name: Amend, Pablo
name: Müller, Martina
name: Mester, Patricia
name: Buechler, Christa
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: adiponectin; disease severity; C-reactive protein; intensive care; bacterial superinfection; COVID-19
subject: 610 Medizin

description: Adiponectin is primarily known for its protective role in metabolic diseases, and it also possesses immunoregulatory properties. Elevated levels of adiponectin have been observed in various inflammatory diseases. However, studies investigating adiponectin levels in the serum of COVID-19 patients have yielded conflicting results. This study aimed to assess serum adiponectin levels in 26 healthy controls, as well as in 64 patients with moderate and 60 patients with severe COVID-19, to determine a potential association between serum adiponectin and the severity of COVID-19. Serum adiponectin levels in severe COVID-19 patients were significantly lower than in those with moderate disease and healthy controls, who exhibited similar serum adiponectin levels. Among patients with moderate disease, positive correlations were observed between serum adiponectin and C-reactive protein levels. Of note, serum adiponectin levels of severe COVID-19 cases were comparable between patients with and without dialysis or vasopressor therapy. Superinfection with bacteria did not exert a notable influence on serum adiponectin levels in patients with severe disease. Patients who were diagnosed with severe COVID-19 and vancomycin-resistant enterococci bacteremia showed a significant reduction in their serum adiponectin levels. An analysis conducted on the entire cohort, including both moderate and severe COVID-19 patients, showed that individuals who did not survive had lower serum adiponectin levels when compared to those who survived. In summary, this study highlights a decrease in serum adiponectin levels in severe COVID-19 cases, indicating the potential utility of adiponectin as an additional biomarker for monitoring disease severity in COVID-19 or critical illnesses in general.
Xenotrypa Bassler 1952
Creators: name: Ernst, Andrej
name: Carrera, Marcelo G.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Bryozoa
Stenolaemata
Cystoporida
Xenotrypidae
Xenotrypa

description: Genus Xenotrypa Bassler, 1952
TYPE SPECIES. — Fistulipora primaeva Bassler, 1911 by subsequent designation (Bassler 1952). Lower Ordovician (?Arenig); Russia.
DIAGNOSIS. — Massive or encrusting colonies. Autozooecia slightly indented by acanthostyles. Diaphragms in autozooecia few to absent. Vesicles irregular, isolating autozooecia. Acanthostyles large, generally in autozooecial walls, some in vesicle walls; centres light to dark in colour. Autozooecial walls indistinctly laminated.
OCCURRENCE. — Lower to Middle Ordovician of Russia and Argentina.
COMPARISON
Xenotrypa Bassler, 1952 differs from Hennigopora Bassler, 1952 in acanthostyles which do not significantly indent into the autozooecia, whereas acanthostyles in Hennigopora strongly indent autozooecia. Furthermore, vesicles usually completely isolate autozooecia in Xenotrypa, whereas the autozooecia in Hennigopora often share a common wall.
description: Published as part of Ernst, Andrej & Carrera, Marcelo G., 2022, A cool-water bryozoan association from the La Pola Formation (Sandbian, Ordovician) of Argentine Precordillera, pp. 563-601 in Geodiversitas 44 (20) on page 568, DOI: 10.5252/geodiversitas2022v44a20, http://zenodo.org/record/6725916
CaMKIIδ-dependent dysregulation of atrial Na+ homeostasis promotes pro-arrhythmic activity in an obstructive sleep apnea mouse model
Creators: name: Hegner, Philipp
name: Ofner, Florian
name: Schaner, Benedikt
name: Gugg, Mathias
name: Trum, Maximilian
name: Lauerer, Anna-Maria
name: Maier, Lars Siegfried
name: Arzt, Michael
name: Lebek, Simon
name: Wagner, Stefan
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: sleep-disordered breathing, reactive oxygen species, CaMKIIδ, Na+ homeostasis, cardiac arrhythmias, obstructive sleep apnea
subject: 610 Medizin

description: Background: Obstructive sleep apnea (OSA) has been linked to various pathologies, including arrhythmias such as atrial fibrillation. Specific treatment options for OSA are mainly limited to symptomatic approaches. We previously showed that increased production of reactive oxygen species (ROS) stimulates late sodium current through the voltage-dependent Na+ channels via Ca2+/calmodulin-dependent protein kinase IIδ (CaMKIIδ), thereby increasing the propensity for arrhythmias. However, the impact on atrial intracellular Na+ homeostasis has never been demonstrated. Moreover, the patients often exhibit a broad range of comorbidities, making it difficult to ascertain the effects of OSA alone.

Objective: We analyzed the effects of OSA on ROS production, cytosolic Na+ level, and rate of spontaneous arrhythmia in atrial cardiomyocytes isolated from an OSA mouse model free from comorbidities.

Methods: OSA was induced in C57BL/6 wild-type and CaMKIIδ-knockout mice by polytetrafluorethylene (PTFE) injection into the tongue. After 8 weeks, their atrial cardiomyocytes were analyzed for cytosolic and mitochondrial ROS production via laser-scanning confocal microscopy. Quantifications of the cytosolic Na+ concentration and arrhythmia were performed by epifluorescence microscopy.

Results: PTFE treatment resulted in increased cytosolic and mitochondrial ROS production. Importantly, the cytosolic Na+ concentration was dramatically increased at various stimulation frequencies in the PTFE-treated mice, while the CaMKIIδ-knockout mice were protected. Accordingly, the rate of spontaneous Ca2+ release events increased in the wild-type PTFE mice while being impeded in the CaMKIIδ-knockout mice.

Conclusion: Atrial Na+ concentration and propensity for spontaneous Ca2+ release events were higher in an OSA mouse model in a CaMKIIδ-dependent manner, which could have therapeutic implications.
Lundomys molitor
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Lundomys
Lundomys molitor

description: Lundomys molitor (Winge 1887)
[Hesperomys] molitor Winge 1887, E Museo Lundii, Vol. 1, 3: 14.
Type Locality: Brazil, Minas Gerais State, cave chamber ("Lapa da Escrivania Nr. 5") near Lagoa Santa.
Vernacular Names: Lund's Amphibious Rat.
Synonyms: Lundomys magnus Hershkovitz 1955.
Distribution: SE Brazil and Uruguay.
Conservation: IUCN – Lower Risk (lc) as Holochilus magnus.
Discussion: Species originally described based on fossils from Recent cave deposits in Minas Gerais, Brazil. Extant populations (described as Holochilus magnus Hershkovitz, 1955) apparently restricted to Rio Grande do Sul, Brazil, and Uruguay (González, 2000 b; Olrog and Lucero, 1981), but Pleistocene fossils known from EC Argentina (Pardiñas, 2000 b). Banded karyotypic comparisons with H. brasiliensis presented by Freitas et al. (1983 a, as H. magnus); synonymy of magnus demonstrated by Voss and Carleton (1993); González (2000 b) recognized magnus as a subspecies for Uruguayan populations.
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1124, DOI: 10.5281/zenodo.7316535
Tennis Injuries Among German League Players: Investigating Patterns and Epidemiology of Acute and Chronic Injuries
Creators: name: Krueckel, Jonas
name: Szymski, Dominik
name: Lenz, Julia Elisabeth
name: Fluegel, Julian
name: Weber, Johannes
name: Achenbach, Leonard
name: Meffert, Rainer
name: Alt, Volker
name: Fehske, Kai
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: tennis, injury, epidemiology, court surface, racquet material, ankle, ligament
subject: 610 Medizin

description: Purpose: While injuries among elite tennis athletes are extensively documented, a notable research gap exists regarding tennis
injuries among club-level players. This study examines tennis injuries in German league players, with a particular emphasis on the
impact of racquet properties and court surfaces, distinguishing between chronic and acute injuries.
Patients and Methods: Retrospectively analyzing data from 600 tennis players over a 1.5-year period, a standardized questionnaire
covered anthropometrics, injury characteristics, equipment usage, and court surface conditions.
Results: The study identified 1012 tennis-related injuries, averaging 1.7 per player. Acute injuries predominantly affected the lower
extremity (56%), with ankle injuries being the most prevalent, and ligaments were the most commonly affected structures (36.4%).
Chronic complaints (reported by 364 athletes) focused on the upper extremity (63.2%), primarily tendon injuries (56.8%). Racket
properties exhibited no significant impact on chronic upper extremity injuries.
Conclusion: This study highlights a high incidence of acute lower extremity injuries, especially ankle ligament injuries, among German
league tennis players. It offers crucial insights for devising targeted injury prevention strategies applicable to amateur, semi-professional,
and professional tennis players, despite finding no significant link between racquet material and chronic upper extremity injuries.
title: Questionnaire d'enquête de Jean Le Dû pour le Nouvel Atlas Linguistique de Basse-Bretagne (NALBB) pour le point d'enquête 006 (Lanrivoaré) à partir d'un enregistrement sonore du 4 décembre 1970
title: Questionnaire d'enquête de Jean Le Dû pour le Nouvel Atlas Linguistique de Basse-Bretagne (NALBB) pour le point d'enquête 006 (Lanrivoaré) à partir d'un enregistrement sonore du 4 décembre 1970
Creators: name: Le Dû, Jean
name: Le Dû, Jean (1938-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022

description: Réponses en breton à un questionnaire portant sur la localisation, la quantité, le temps qui passe, le temps qu'il fait, les éléments, les plantes et les fruits, les mammifères sauvages, les oiseaux sauvages, autres animaux, les animaux familiers, la ferme, les hommes, les activités agricoles.
description: Source: Le Dû, Jean. (2010, July 9). NALBB: Enquête dialectologique à Lanrivoaré (2) (Version 1). Centre de Recherche Bretonne et Celtique. https://doi.org/10.34847/COCOON.2D66F249-DA17-35BA-AA48-30092574085C
description: Source: Centre de Recherche Bretonne et Celtique (CRBC), fonds Jean Le Dû (1938-2020), JLD.001.006
description: Source: Le Dû, Jean. (2010, July 9). NALBB: Enquête dialectologique à Lanrivoaré (1) (Version 1). Centre de Recherche Bretonne et Celtique. https://doi.org/10.34847/COCOON.1D165CE3-B667-32D2-8419-22A4F8696966
description: Provenance: Ce document provient du fonds Jean Le Dû (1938-2020) conservé au Centre de recherche bretonne et celtique (Brest)
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description: JLD.001.006.pdf
Zoologia politica
Creators: name: Guglielminetti, Enrico
Publisher: name: Spazio Filosofico
Year: 2018

description: The difference between the right and the left dwindles, appears as progressively unclear. With respect to the right and the left, one could say what Augustine maintains about time. If no one asks us what the right and the left are, we know it well; yet if someone asks us, we no longer know. What kind of odd mutant animals have the right and the left become, or are they? In any case, such shock concepts are present and active within the public space; therefore they are particularly relevant to Spazio Filosofico.


The essays that have been gathered in this issue of Spazio Filosofico (some from the right, some from the left, and some from neither) try to cast some light on this topic. With respect to their subject matter, they behave a little like Goethe; when having to distinguish among natural forms that were diverse and yet similar, intertwined, and related to one another, Goethe admitted to his frequent difficulties since he did not “dare plant his stake or draw a boundary line” and could “never hope for an indisputable application” of norms and definitions. Goethe asked: “What should we think of some many irregular malformations?”
description: Spazio Filosofico, 22. Destra e sinistra
Political Zoology
Creators: name: Guglielminetti, Enrico
Publisher: name: Spazio Filosofico
Year: 2018

description: The difference between the right and the left dwindles, appears as progressively unclear. With respect to the right and the left, one could say what Augustine maintains about time. If no one asks us what the right and the left are, we know it well; yet if someone asks us, we no longer know. What kind of odd mutant animals have the right and the left become, or are they? In any case, such shock concepts are present and active within the public space; therefore they are particularly relevant to Spazio Filosofico.


The essays that have been gathered in this issue of Spazio Filosofico (some from the right, some from the left, and some from neither) try to cast some light on this topic. With respect to their subject matter, they behave a little like Goethe; when having to distinguish among natural forms that were diverse and yet similar, intertwined, and related to one another, Goethe admitted to his frequent difficulties since he did not “dare plant his stake or draw a boundary line” and could “never hope for an indisputable application” of norms and definitions. Goethe asked: “What should we think of some many irregular malformations?”
description: Spazio Filosofico, 22. Destra e sinistra
Destra e sinistra. Due concetti sospesi fra essenze, tipi ideali e convenzioni
Creators: name: Tarchi, Marco
Publisher: name: Spazio Filosofico
Year: 2018

description: For decades, in the philosophical as well as the historical, political theory, and sociological fields, a debate has developed on two related albeit distinct themes: namely, on the one hand, the cultural and ideological contents that should be associated with the notions of “the right” and “the left” and on the other, the ability of these two concepts to represent the cleavages that currently determine political affiliations and electoral behaviors. Despite the many attempts to answer these questions, the scientific community has reached no agreement on the topic. The essay aims at explaining why none of the approaches that have been adopted so far has been able to attain the proposed intents and highlights the limits of the validity of a “geographical-axial” conception of politics supporting such an oppositional pair.
description: Spazio Filosofico, 22. Destra e sinistra
Alexithymia as a mediator between adverse childhood events and the development of psychopathology: a meta-analysis
Creators: name: Kick, Lorenz
name: Schleicher, Daniel
name: Ecker, Angelika
name: Kandsperger, Stephanie
name: Brunner, Romuald
name: Jarvers, Irina
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: child abuse, alexithymia, psychopathology, TAS-20, CTQ, SCL-90, BSI
subject: 610 Medizin

description: Introduction: Victims of child abuse have an elevated risk of developing mental health issues later in life. Several variables have been suggested as mediators of this correlation, but little is known about the possible influence of alexithymia. Alexithymia is a sub-clinical personality trait that manifests as difficulties recognizing and verbalizing emotions.

Methods: In this study, two separate meta-analyses were conducted using questionnaire data, and Pearson correlations for overall effects were estimated.

Results: The correlation between child abuse and alexithymia showed to be significant (r = .26), as did the correlation between alexithymia and general psychopathology (r = .44). Further analyses revealed no indication for possible publication bias. When investigating differences between various subtypes of child maltreatment, each subtype significantly correlated with alexithymia. Emotional abuse, emotional neglect, and physical neglect had stronger correlations than physical and sexual abuse.

Discussion: These results suggest that alexithymia plays a mediating role, at least in part, in the relationship between experiences of child abuse and general psychopathology in adulthood. Therefore, alexithymia may be relevant to further research and deserves attention in the prevention of and therapy for mental health issues in victims of child abuse.
Latin Majuscule Writing with inclined axis in Herculaneum papyri
Creators: name: Marichal, Robert
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015

description: vue 117
description: "Study of the following Latin papyri: P.Herc. 78, 217, 219, 279, 395, 396, 506, 525, 1208 (cornice 2), 1763. All papyri are listed on the cover page of the main folder; some papyri are marked with the word 'micro' written with a different (pink) ink ; the indication 'Vu 58' is written at the bottom of the list (same ink), and a bibliographical reference is quoted in relation to P.Herc. 217"
description: Source: 4MAR_9_2_5-14
description: Relation: 4MAR_42_4-5
description: created: n.d., 1957
Megalomys Trouessart 1881
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Megalomys

description: Megalomys Trouessart 1881
Megalomys Trouessart 1881, Le Naturaliste, 1: 357.
Type Species: Mus pilorides Desmarest 1826
Synonyms: Moschomys Trouessart 1903; Moschophoromys Elliot 1904.
Species and subspecies: 2 species:
Species Megalomys desmarestii (Fischer 1829)
Species Megalomys luciae Major 1901
Discussion: Oryzomyini. Derived postcranial traits of Megalomys are consistent with its association within Sigmodontinae sensu stricto (lack of entepicondylar foramen, tuberculum of 1 st rib contacting both the 1 st thoracic and 7 th cervical vertebrae; as per M. desmarestii, BMNH 1850.11.30.6); other cranial characters more narrowly point to its membership within Oryzomyini (long palate with prominent posterolateral pits, absence of alisphenoid strut; as per M. luciae, BMNH 53.12.16.2, and M. desmarestii, BMNH 50.11.30.6 and 55.12.24.201), as diagnosed by Voss and Carleton (1993). A combination of features suggests that the close relatives of Megalomys may be sought among certain derived oryzomyines, such as Oryzomys sensu stricto, or Nectomys (e.g., thenar and hypothenar pads present but barely indicated; molars brachyodont and pentalophodont, with M1/m1 four-rooted; supraorbital and temporal ridging well developed and reflected dorsally; carotid circulation derived).
Named as a subgenus of the all-inclusive Hesperomys, later associated with Holochilus by Thomas (1884) or Oryzomys by Major (1901), and subsequently recognized as an oryzomyine genus endemic to the Lesser Antilles (Ellerman, 1941; Hall, 1981; Steadman and Ray, 1982; Tate, 1932 c). Does not include the extinct Galápagos endemic curoi, described as a species of Megalomys by Niethammer (1964); see Steadman and Ray (1982) and account of Megaoryzomys. Morphology redescribed and taxonomy revised by Ray (1962) as a subgenus of Oryzomys, following the undeveloped opinions of Osgood (1947) and Hershkovitz (1948 b). The four nominal species (audreyae Hopwood, 1926; curazensis Hooijer, 1959; desmarestii Fischer, 1829; luciae Forsyth Major, 1901) are extinct, possibly all due to anthropogenic causes, but M. desmarestii and M. luciae, listed below, persisted into the middle, perhaps late, 1800s (Ray, 1962; Woods, 1989). Known from Pleistocene-Holocene fossils, Pre-Columbian midden deposits, and a few modern specimens (Ray, 1962). See G. M. Allen (1942) for compilation of meagre historical accounts.
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1124, DOI: 10.5281/zenodo.7316535
HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice
Creators: name: Albert, Veruschka
name: Bruss, Christina
name: Tümen, Deniz
name: Piendl, Gerhard
name: Weber, Florian
name: Dahl, Edgar
name: Seitz, Stephan
name: Ortmann, Olaf
name: Wege, Anja K.
name: Brockhoff, Gero
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: hormone receptor positive (HR+) breast cancer; human epidermal growth factor receptor related (HER4); tamoxifen; abemaciclib; humanized tumor mice (HTM)
subject: 610 Medizin

description: The impact of the HER4 receptor on the growth and treatment of estrogen receptor-positive
breast cancer is widely uncertain. Using CRISPR/Cas9 technology, we generated stable HER4 knockout
variants derived from the HER4-positive MCF-7, T-47D, and ZR-75-1 breast cancer cell lines. We
investigated tumor cell proliferation as well as the cellular and molecular mechanisms of tamoxifen,
abemaciclib, AMG232, and NRG1 treatments as a function of HER4 in vitro. HER4 differentially
affects the cellular response to tamoxifen and abemaciclib treatment. Most conspicuous is the increased
sensitivity of MCF-7 in vitro upon HER4 knockout and the inhibition of cell proliferation by
NRG1. Additionally, we assessed tumor growth and immunological effects as responses to tamoxifen
and abemaciclib therapy in humanized tumor mice (HTM) based on MCF-7 HER4-wildtype and the
corresponding HER4-knockout cells. Without any treatment, the enhanced MCF-7 tumor growth
in HTM upon HER4 knockout suggests a tumor-suppressive effect of HER4 under preclinical but
human-like conditions. This phenomenon is associated with an increased HER2 expression in MCF-7
in vivo. Independent of HER4, abemaciclib and tamoxifen treatment considerably inhibited tumor
growth in these mice. However, abemaciclib-treated hormone receptor-positive breast cancer patients
with tumor-associated mdm2 gene copy gains or pronounced HER4 expression showed a reduced
event-free survival. Evidently, the presence of HER4 affects the efficacy of tamoxifen and abemaciclib
treatment in different estrogen receptor-positive breast cancer cells, even to different extents, and is
associated with unfavorable outcomes in abemaciclib-treated patients.
Case report: Local bacteriophage therapy for fracture-related infection with polymicrobial multi-resistant bacteria: hydrogel application and postoperative phage analysis through metagenomic sequencing
Creators: name: Alt, Volker
name: Gessner, André
name: Merabishvili, Maya
name: Hitzenbichler, Florian
name: Mannala, Gopala Krishna
name: Peterhoff, David
name: Walter, Nike
name: Pirnay, Jean-Paul
name: Hiergeist, Andreas
name: Rupp, Markus
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: bacteriophage, fracture-related infection, metagenomic, Masquelet, hydrogel
subject: 610 Medizin

description: Fracture-related infections can be challenging, particularly with concomitant severe bone defects and multi-resistant microorganisms. We present a case of a 42-year-old patient with a fracture-related infection following a war injury from a gunshot, resulting in a 12-cm subtrochanteric segmental bone defect and the detection of four different multi-resistant Gram-negative bacteria. Due to antibiotic drug resistance, treatment with bacteriophages was considered. Phage susceptibility testing revealed the activity of a commercially available bacteriophage cocktail (Intesti bacteriophage, Eliava Institute, Tbilisi, Georgia). This phage cocktail was included in a modified two-stage Masquelet technique. During the first intervention, the bone was debrided and samples for microbiological and phage testing were harvested. The indwelling intramedullary rod was removed, and the bone defect was filled with a PMMA spacer loaded with colistin and the bone stabilized with a plate. During the second procedure, the PMMA spacer was removed and a silver-coated angular stable plate was implanted. The bone defect was filled with a fibular autograft and allograft cancellous bone chips. At the end of the procedure, the Intesti bacteriophage cocktail was injected into a DAC hydrogel and this bacteriophage hydrogel composite was then put onto the angular stable plate. Postoperatively the wound fluid was collected over 72 h, and high-throughput metagenomic sequencing was performed. This showed a time-dependent release of the bacteriophages in the wound fluid, with a relatively high concentration after 12 h, decreasing to DNA copies of 0 after 72 h. Furthermore, we have assessed the release of phages from DAC gel and the effect of DAC gel on the phages in vitro. The results showed a stable and rapid release of phages from the DAC gel (~1×103 PFU/mL). The clinical course of the patient showed no relapse of the infection with good bone consolidation of the bone defect after 1 year without the need for any surgical revision. To the best of our knowledge, this is the first case that shows the detection of bacteriophage DNA copies by high-throughput metagenomics sequencing in a patient with a complex fracture-related infection. Successful treatment of this case encourages further investigation of bacteriophage therapy in patients with complex bone and joint infections.
Megalomys desmarestii
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Megalomys
Megalomys desmarestii

description: Megalomys desmarestii (Fischer 1829)
[Megalomys] desmarestii (Fischer 1829), Synopsis Mamm.: 316.
Type Locality: West Indes, Lesser Antilles, Martinique.
Vernacular Names: Desmarest's Pilorie.
Synonyms: Megalomys pilorides (Desmarest 1826); Megalomys piloris (Major 1901).
Distribution: Known only from Martinique.
Conservation: IUCN – Extinct.
Discussion: As compared with M. luciae (BMNH 53.12.16.2, the holotype), the cranium of M. desmarestii (BMNH 50.11.30.6, 55.12.24.201) is generally larger in all dimensions, its m3 larger relative to m2, and the upper incisors yellowish-orange instead of plain orange.
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1124, DOI: 10.5281/zenodo.7316535
Characteristics and Outcome of Surgically Treated Patients with Intradural Extra- and Intramedullary Spinal Metastasis—A Single-Center Retrospective Case Series and Review
Creators: name: Salvotti, Hanna Veronika
name: Lein, Alexander
name: Proescholdt, Martin
name: Schmidt, Nils-Ole
name: Siller, Sebastian
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: metastasis; intradural; intramedullary; extramedullary; outcome; survival
subject: 610 Medizin

description: Objective: Intradural spinal metastases are considered rare. At present, limited information
is available on incidence, surgicalmanagement, and outcomes. Methods: We conducted a retrospective
patient chart review from 2002 to 2024, identifying all patients surgically treated for intradural spinal
metastases. Clinical, surgical and survival data were collected and compared to literature data for
patients surgically treated for extradural spinal metastases. Results: A total of 172 patients with
spinal metastases were identified with 13 patients meeting inclusion criteria (7.6%). The mean age
at diagnosis of intradural spinal metastases was 52 ± 22 years, with diverse primaries including
lung (n = 3), breast (n = 2), sarcoma (n = 2), and six unique entities. Intradural spinal metastasis
was diagnosed on average of 3.3 years after primary diagnosis. In total, we observed five (38%)
intradural-extramedullary and eight (62%) intramedullary metastases, located in the cervical (38.5%),
thoracic (46.1%) and lumbar spine (15.4%). The most common preoperative symptoms were pain,
sensory changes, and gait ataxia (each 76.9%). Gross total resection was achieved in 54%, and local
tumor control in 85%. Postoperatively, 92% exhibited clinical improvement or stability. Most frequent
adjuvant treatment was radio- and/or chemotherapy in 85%. The average survival after operation for
spinal intradural metastases was 5 months, ranging from 1 month to 120 months. The location of the
intradural metastasis in the cervical spine was associated with a significantly more favorable survival
outcome (compared to thoracic/lumbar location, p = 0.02). Conclusions: Intradural location of spinal
metastases is rare (7.6%). Even so, surgical resection is safe and effective for neurological improvement,
and survival appears lower compared to the reported survival of extradural spinal metastases.
Expression of the plasma membrane citrate carrier (pmCiC) in human cancerous tissues—correlation with tumour aggressiveness
Creators: name: Schwertner, Barbara
name: Dahdal, George
name: Jagla, Wolfgang
name: Grossmann, Luis
name: Drexler, Konstantin
name: Krahn, Michael P.
name: Evert, Katja
name: Berneburg, Mark
name: Haferkamp, Sebastian
name: Ziegler, Christine
name: Parkinson, Eric K.
name: Zahn, Grit
name: Mycielska, Maria E.
name: Gaumann, Andreas
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: biomarker, cancer, citrate, tumour microenvironment, plasma membrane citrate carrier (pmCiC)
subject: 610 Medizin

description: We have recently shown that cancer cells of various origins take up
extracellular citrate through the plasma membrane citrate carrier (pmCiC),
a specific plasma membrane citrate transporter. Extracellular citrate is
required to support cancer cell metabolism, in particular fatty acid
synthesis, mitochondrial activity, protein synthesis and histone acetylation.
In addition, cancer cells tend to acquire a metastatic phenotype in the
presence of extracellular citrate. Our recent study also showed that
cancer-associated stromal cells synthesise and release citrate and that this
process is controlled by cancer cells. In the present study, we evaluated the
expression of pmCiC, fibroblast activation protein-α (FAP) and the
angiogenesis marker cluster of differentiation 31 (CD31) in human cancer
tissues of different origins. In the cohort studied, we found no correlation
between disease stage and the expression of FAP or CD31. However, we
have identified a clear correlation between pmCiC expression in cancer
cells and cancer-associated stroma with tumour stage. It can be
concluded that pmCiC is increased in cancer cells and in cancersupporting
cells in the tumour microenvironment at the later stages of
cancer development, particularly at the metastatic sites. Therefore, pmCiC
expression has the potential to serve as a prognostic marker, although further
studies are needed.
Touching the unconscious in the unconscious – hypnotic communication with unconscious patients
Creators: name: Hansen, Ernil
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: hypnosis, coma, resuscitation, general anesthesia, communication, intensive care, unconsciousness, suggestions
subject: 610 Medizin

description: If hypnosis means contact to the unconscious to modulate psychological and physiological functions by means of suggestions, and if this is facilitated by attenuation of the critical mind, then the question arises as to whether suggestions also have an effect when waking consciousness is otherwise eliminated, namely by coma or anesthesia. A prerequisite would be perception, which actually is evidenced by reports of patients after traumatic brain injury, artificial coma, resuscitation or general anesthesia. Moreover, posttraumatic stress disorder (PTSD) frequently observed after these medical situations is hardly explainable without some sort of awareness under such conditions. Even advanced neurophysiological diagnostic cannot yet rule out consciousness or sensory processing. Especially reference to perception during unconsciousness is given by the results of a recent multicenter study on the effects of hypnotic communication with patients under controlled adequate deep general anesthesia. The observed reductions in incidence and severity of postoperative pain, opioid use, nausea and vomiting cannot be explained by the reaction of a few but only by a considerable proportion of patients. This leads to a strong plea for a more careful treatment of unconscious patients in the emergency room, operating theater or intensive care unit, for the abandonment of the restriction of therapeutic communication to awake patients, and for new aspects of communication and hypnosis research. Obviously, loss of consciousness does not protect against psychological injury, and continuation of communication is needed. But how and what to talk to unconscious patients? Generally addressing the unconscious mind with suggestions that generally exert their effects unconsciously, hypnotic communication appears to be the adequate language. Especially addressing meaningful topics, as derived from the basic psychological needs and known stressors, appears essential. With respect to negative effects by negative or missing communication or to the proposed protective and supporting effects of therapeutic communication with patients clinically rated as unconscious, the role of consciousness is secondary. For the effects of perceived signals and suggestions it does not matter whether consciousness is absent, or partial, or unrecognized present.