cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ICDI Competence Centre for Open Science, FAIR and EOSC - Mission, Strategy and Action Plan
Creators: name: Lazzeri, Emma
name: Tanlongo, Federica
name: Pavone, Gina
name: Alpi, Federico
name: Ansuini, Alessio
name: Bertazzon, Elis
name: Bonaccorsi, Daniele
name: Cappelluti, Federica
name: Casati, Sara
name: Castelli, Donatella
name: Cippitani, Roberto
name: Colcelli, Valentina
name: Costantini, Alessandro
name: Cozzini, Stefano
name: Degl'Innocenti, Emiliano
name: Di Donato, Francesca
name: Di Giorgio, Sara
name: Fava, Ilaria
name: Fiore, Sandro
name: Forni, Monica
name: Galimberti, Paola
name: Giglia, Elena
name: Giorgetti, Alessandra
name: Kurapati, Shalini
name: Landoni, Marco
name: Lavitrano, Marialuisa
name: Marras, Cristina
name: Niccolucci, Franco
name: Occioni, Marisol
name: Osmenaj, Elda
name: Paolini, Gabriella
name: Pasquale, Valentina
name: Petrillo, Caterina
name: Pugliese, Roberto
name: Ripepi, Ermann
name: Rivoira, Giorgia
name: Rossi, Giorgio
name: Salon, Stefano
name: Sarretta, Alessandro
name: Sartori, Alberto
name: Spiga, Daniele
name: Tamagno, Donatella
name: Tammaro, Anna Maria Università di Modena e Reggio Emilia
name: Vellico, Michela
name: Vignocchi, Marialaura
name: Zane, Donatella
Publisher: name: Zenodo
Year: 2021
Subjects: Competence Centre
EOSC
FAIR
Open Science

description: This document presents the mission and strategy of the Italian Competence Centre on Open Science, FAIR, and EOSC. The Competence Centre is an initiative born within the Italian Computing and Data Infrastructure (ICDI), a forum created by representatives of major Italian Research Infrastructures and e-Infrastructures, with the aim of promoting sinergies at the national level, and optimising the Italian participation to European and global challenges in this field, including the European Open Science Cloud (EOSC), the European Data Infrastructure (EDI) and HPC. This working paper depicts the mission and objectives of the ICDI Competence Centre, a network of experts with various skills and competences that are supporting the national stakeholders on topics related to Open Science, FAIR principles application and participation to the EOSC. The different actors and roles are described in the document as well as the activities and services offered, and the added value each stakeholder can find the in Competence Centre. The tools and services provided, in particular the concept for the portal, though which the Centre will connect to the national landscape and users, are also presented. This record is the english translation of the original Italian (2021). Competence Centre ICDI per Open Science, FAIR, ed EOSC - Mission, Strategia e piano d'azione. Zenodo. https://doi.org/10.5281/zenodo.5071055
description: This record is the english translation of the original Italian (2021). Competence Centre ICDI per Open Science, FAIR, ed EOSC - Mission, Strategia e piano d'azione. Zenodo. https://doi.org/10.5281/zenodo.5071055
Der Einfluss von Coping-Strategien auf das Schmerzerleben von Tumorpatienten in der Radioonkologie
Creators: name: Drechsel, Ulrike Ingrid
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2012
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 616
subject: 610

description: In einer retrospektiven Beobachtungsstudie wurden an 216 Patienten der Verlauf des Schmerz-Scores sowie der Zusammenhang zwischen Schmerz-Score und Analgetikaeinnahme während des stationären Aufenthaltes untersucht. Es fand sich eine signifikante Abnahme des Schmerz-Scores zwischen Aufnahme und Entlassung, jedoch nur eine geringe Korrelation zwischen Schmerz-Score und analgetischer Medikation. Daher wurde folgende Hypothese generiert: Das Schmerzerleben wird möglicherweise durch individuelle Coping-Strategien beeinflusst. In einer prospektiven Befragungsstudie wurden an 88 Patienten mit Kopf-Hals-Tumoren und Rektum-Karzinomen Kontrollüberzeugungen und kognitive Reaktionen in Schmerzsituationen erforscht. Die logistische Regressionsanalyse ergab, dass Geschlecht, Primärtumor und Ausprägung fatalistisch-externaler Kontrollüberzeugungen das Schmerzerleben beeinflussen. Die Patienten zeigten bei den kognitiven Reaktionen die höchsten Ausprägungen auf den Subskalen Durchhalteappell, Bagatellisieren und Katastrophisieren. Die einzelnen Kognitionen korrelierten jedoch nicht signifikant mit dem Schmerz-Score.
description: Within a retrospective observation study of 216 patients course of pain and relationship between painand use of pain medication during inpatient radiation therapy were observed. Pain decreased significantly between admission and discharge but only little correlation was found between intensity of pain and pain medication. Following hypothesis was generated: Experiencing pain might be influenced by individual coping-strategies. Within a prospective survey study locus of control and specific pain coping strategies of 88 patients with head and neck cancer and rectal cancer were investigated. Logistic regression analysis revealed gender, primary tumour and level of chance locus of control as significant predictors for experiencing pain. Patients showed highest levels of endurance coping, minimization and catastrophizing. No significant correlations between individual copingstrategies and pain intensity were found.
Quantum gravity effects on compact star cores
Creators: name: Wang, Peng
name: Yang, Haitang
name: Zhang, Xiuming
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Using the Tolman-Oppenheimer-Volkoff equation and the equation of state of zero temperature ultra-relativistic Fermi gas based on generalized uncertainty principle (GUP), the quantum gravitational effects on the cores of compact stars are discussed. Our results show that ${2m(r)}/ {r}$ varies with $r$. Quantum gravity plays an important role in the region $ r\sim 10^3 r_0$, where $r_0\sim β_0 l_p $, $l_p$ is the Planck length and $β_0$ is a dimensionless parameter accounting for quantum gravity effects. Furthermore, near the center of compact stars, we find that the metric components are $g_{tt}\sim r^4$ and $g_{rr}=[1-{r}^2/(6r_0^2)]^{-1}$. All these effects are different from those obtained from classical gravity. These results can be applied to neutron stars or denser ones like quark stars. The observed masses of neutron stars ($\leq 2M_\odot$) indicate that $β_0$ can not exceed $10^{37}$, not as good as the upper bound $β_0<10^{34}$ from simple electroweak consideration. This means that incorporating either quantum gravity effects or nuclear interactions, one obtains almost the same mass limits of neutron stars.
description: 12 pages, 1 figure, added brief review on compact stars configurations, abstract expanded, references added, typo corrected, published version
Synthese, Charakterisierung und biologische Evaluation von MDR-Modulatoren und HIV-1 Proteaseinhibitoren mit 1,4-Dihydropyridin-Grundstruktur
Creators: name: Baumert, Christiane
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2012
Subjects: subject: HIV
subject: Multidrug-Resistenz
subject: Glykoproteine
subject: Enzyminhibitor
subject: Online-Publikation
subject: Hochschulschrift
subject: 610
subject: 615

description: P-Glycoprotein (P-gp) vermittelte Multidrug Resistenzen (MDR) sind in der Krebstherapie aber auch bei verschiedenen anderen Erkrankungen, wie Epilepsie oder Demenz, nach wie vor ein großes Problem. Auch in der HIV-Therapie spielt P-gp eine therapiebeeinflussende Rolle. Ein gleichzeitiger Angriff an HIV-Zielproteinen, wie HIV-1-Protease und P-gp könnten daher einen großen Fortschritt in der HIV-Therapie bedeuten. Die in dieser Arbeit synthetisierten dimeren 1,4-Dihydropyridin-Derivate zeigten gute Hemmeigenschaften an beiden Zielstrukturen. Die monomeren Strukturen zeigten eine gute P-gp-Inhibition. Die Hemmung von P-gp wurde durch FACS-Untersuchungen und Resistenzaufhebungs-Assays an einer Maus-T-Lymphom-Zelllinie belegt. Eine ymmetrische Molekülstruktur der dimere Derivate war für die P-gp-Inhibition von Vorteil. Hier wird der C2-pseudosymmetrische Aufbau des Transporters ausgenutzt. Die Homo- und Heterodimere zeigten zusätzlich eine sehr gute Hemmung der HIV-1-Protease in einem fluorimetrischen in-vitro Assay. Die symmetrische Struktur der Protease verlangt nicht zwangsläufig nach einer symmetrischen Struktur der Inhibitoren. Durch Anpassung der flexiblen Enzymstruktur sind auch asymmetrische Bindungen der Heterodimere möglich. Durch verschiedene Substituenten in unterschiedlicher Stellung an den Monomeren und Dimeren konnten Struktur-Wirkungs-Beziehungen abgeleitet werden.
description: Today, P-glycoprotein (P-gp) mediated multidrug resistance (MDR) is still a major problem in therapy of cancer and other diseases as epilepsy or dementia. An effective modulator of MDR is outstanding. P-gp plays also an important role in HIV-therapy. A dual mode of action as inhibiting both, HIV target structures, like HIV-1 protease and P-gp, can be advantageous in HIV-therapy. 1,4-Dihydropyridine derivatives combine both characteristics, inhibition of P-gp and HIV-1-protease. Monomeric as well as homo- and heterodimeric structures and 1,4-dihydroquinolines showed potent P-gp inhibiting properties as prooved in FACS analysis and cell assays. A symmetric structure of the dimeric compounds was advantageous for P-gp inhibition, due to the C2-pseudosymmetry of the proteinstructure. Unlike, symmetric homodimers and asymmetric heterodimers showed potent HIV protease inhibition, messured in a fluorimetric in vitro assay. The flexibility of the protease structure allows the structural adaption to the inhibitor molecule. Varied substituents have been introduced to the aromatic residues of the dihydropyridine derivatives. Structure activity relations are discussed.
Increasing Forests and Quadrangulations via a Bijective Approach
Creators: name: Bettinelli, Jérémie
Publisher: name: arXiv
Year: 2012
Subjects: subject: Probability (math.PR)
subject: Discrete Mathematics (cs.DM)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: In this work, we expose four bijections each allowing to increase (or decrease) one parameter in either uniform random forests with a fixed number of edges and trees, or quadrangulations with a boundary having a fixed number of faces and a fixed boundary length. In particular, this gives a way to sample a uniform quadrangulation with n + 1 faces from a uniform quadrangulation with n faces or a uniform forest with n+1 edges and p trees from a uniform forest with n edges and p trees.
Finite Scale Lyapunov Analysis of Temperature Fluctuations in Homogeneous Isotropic Turbulence
Creators: name: de Divitiis, Nicola
Publisher: name: arXiv
Year: 2012
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: This study analyzes the temperature fluctuations in incompressible homogeneous isotropic turbulence through the finite scale Lyapunov analysis of the relative motion between two fluid particles. The analysis provides an explanation of the mechanism of the thermal energy cascade, leads to the closure of the Corrsin equation, and describes the statistics of the longitudinal temperature derivative through the Lyapunov theory of the local deformation and the thermal energy equation. The results here obtained show that, in the case of self-similarity, the temperature spectrum exhibits the scaling laws $κ^n$, with $n \approx{-5/3}$, ${-1}$ and ${-17/3} ÷-11/3$ depending upon the flow regime. These results are in agreement with the theoretical arguments of Obukhov--Corrsin and Batchelor and with the numerical simulations and experiments known from the literature. The PDF of the longitudinal temperature derivative is found to be a non--gaussian distribution function with null skewness, whose intermittency rises with the Taylor scale Péclet number. This study applies also to any passive scalar which exhibits diffusivity.
description: 37 pages, 11 figures
Scanamorphos: a map-making software for Herschel and similar scanning bolometer arrays
Creators: name: Roussel, Hélène
Publisher: name: arXiv
Year: 2012
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Scanamorphos is one of the public softwares available to post-process scan observations performed with the Herschel photometer arrays. This post-processing mainly consists in subtracting the total low-frequency noise (both its thermal and non-thermal components), masking high-frequency artefacts such as cosmic ray hits, and projecting the data onto a map. Although it was developed for Herschel, it is also applicable with minimal adjustment to scan observations made with some other imaging arrays subjected to low-frequency noise, provided they entail sufficient redundancy; it was successfully applied to P-Artemis, an instrument operating on the APEX telescope. Contrary to matrix-inversion softwares and high-pass filters, Scanamorphos does not assume any particular noise model, and does not apply any Fourier-space filtering to the data, but is an empirical tool using purely the redundancy built in the observations -- taking advantage of the fact that each portion of the sky is sampled at multiple times by multiple bolometers. It is an interactive software in the sense that the user is allowed to optionally visualize and control results at each intermediate step, but the processing is fully automated. This paper describes the principles and algorithm of Scanamorphos and presents several examples of application.
description: This is the final version as accepted by PASP (on July 27, 2013). A copy with much better-quality figures is available on http://www2.iap.fr/users/roussel/herschel/
Dark Forces and Dark Matter in a Hidden Sector
Creators: name: Andreas, Sarah
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Hidden sectors in connection with GeV-scale dark forces and dark matter are not only a common feature of physics beyond the Standard Model such as string theory and SUSY but are also phenomenologically of great interest regarding recent astrophysical observations. The hidden photon in particular is also searched for and constrained by laboratory experiments, the current status of which will be presented here. Furthermore, several models of hidden sectors containing in addition a dark matter particle will be examined regarding their consistency with the dark matter relic abundance and direct detection experiments.
description: 4 pages, 3 figures, contribution to the proceedings of the "7th Patras Workshop on Axions, WIMPs and WISPs", Greece, 26 June - 1 July 2011, v2: matches published version
Novel fabrication of flexible microelectrodes with macroporous platinum film using latex polystyrene sphere template
Creators: name: Oyunerdene, Nominerdene
Publisher: name: University of British Columbia
Year: 2014

description: With great strides in neuroscience that have been made in the past decade, further understandings of complex neural systems require extensive neural information from chronic implantation of biocompatible neural devices. Polyimide-based flexible microelectrode arrays were one of the earlier biocompatible neural devices due to its mechanical impedance matching with brain tissue. In this work, we propose to incorporate non-conventional laser ablation method for fabrication of flexible biocompatible microelectrodes. We also present a novel approach to modifying flexible microelectrodes with macroporous platinum film using latex polystyrene sphere template. Maskless laser ablation was used to pattern the electrode, and probe definition as well creating the contact openings of flexible polyimide electrodes. Laser ablation is a non-photolithographic method which does not require conventional cleanroom environment and is ideal for rapid prototyping of devices. An ordered polystyrene bead template was deposited by simple pipetting of bead solution over gold contact openings and evaporating in ambient room setting. Pulsed-potentiostatic mode electrochemical deposition of platinum through the polystyrene bead template resulted in increase in effective surface area of electrodes. The impedance of the platinum modified electrodes increased by two orders of magnitude compared to unmodified electrodes. Synergetic modification of microelectrodes with macroporous platinum film and polymer-brush coating can lead to fabrication of highly biocompatible microelectrode with low impedance characteristics.
Modifikation der Sialylierung von Erythropoietin durch nichtphysiologische Acylmannosamine und ihr Einfluss auf die Resistenz gegenüber Sialidase A
Creators: name: Werner, Anselm Cornelius
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2013
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 610
subject: 612

description: Sialinsäuren sind ein typischer Bestandteil der N-Glykane der Säugetiere. Sie erhöhen z. B. die Halbwertszeit von Serumproteinen, werden aber mit der Zeit von Sialidasen abgespalten. Infolgedessen werden die Glykoproteine von Asialoglykoproteinrezeptoren der Leber gebunden und aus dem Blutstrom entfernt. In dieser Arbeit wurde die Sialylierung von in CHO-S-Zellen exprimiertem Erythropoietin durch Zugabe der modifizierten Sialinsäurevorläufer N-Pentanoylund N-Propanoylmannosamin zur Zellkultur verändert und massenspektrometrisch nachgewiesen. Die Stabilität der Sialylierung wurde in einem Degradationsassay mit Sialidase A, der durch eine 2D-Gelelektrophorese ausgewertet wurde, überprüft. Es stellte sich heraus, dass die neuartigen Sialinsäuren, insbesondere N-Pentanoylneuraminsäure, im Vergleich zur nativen NAcetylneuraminsäure resistenter gegenüber dem Abbau durch Sialidase A sind, wodurch sich die Halbwertszeit therapeutischer Glykoproteine verlängern ließe.
description: The terminal positions of N-linked complex glycans in mammals are typically occupied by sialic acids. The presence of sialic acid is crucial for functionality and affects the half-life of glycoproteins. However, glycoproteins in the bloodstream become desialylated over time and are recognized by the asialoglycoprotein receptors via the exposed galactose and targeted for degradation. Non-natural sialic acid precursors can be applied to the cell culture medium to engineer the glycosylation side chains by biochemically introducing new non-natural terminal sialic acids. The sialylation of erythropoietin (EPO) was analyzed. By feeding cells with Npropanoyl or N-pentanoyl mannosamine it was possible to incorporate N-propanoyl or Npentanoyl neuraminic acid in significant amounts into EPO. Using a degradation assay with sialidase A, a higher resistance of EPO to sialidase after incorporation of N-propanoyl and most notably N-pentanoyl neuraminic acid was observed.
title: The distinctive relationship between sexual ecstasy and spiritual ecstasy for heterosexual, lesbian, gay, bisexual and transgendered clergy of the Church of England: Integrating Transpersonal Awareness with an Interpretative Phenomenological Analysis.
Creators: name: Smith, S
Publisher: name: Liverpool John Moores University
Year: 2021

description: Twenty-two participants who identified as heterosexual, lesbian, gay, bisexual or transgendered clergy of the Church of England were recruited and interviewed using a semi-structured interview. The methodology employed incorporated Transpersonal Awareness with an Interpretative Phenomenological Analysis. After several levels of analysis the following superordinate themes emerged: (a) twenty of these participants organised their sexuality and spirituality in a dialectical or unified relationship; (b) twelve of these reported a direct mystical union with God through the veil of sexual ecstasy; (c) all twelve reported that these experiences have been transformative leading to an expanded and inclusive sense of self and other, which has also enhanced their ministry; (d) rituals and symbols that reflect the distinctive relationship between sex and spirit are needed to reflect and confirm heterosexual and LGBT participants’ lived experiences; and, (e) the House of Bishops of the Church of England continues to place spirituality and sexuality in a dualistic relationship, relegating the latter into the shadows of human experience, causing a deep sense of rejection and oppression for lesbian, gay, bisexual and transgendered clergy who faithfully serve as priests within the Church of England.
Linear embeddings of $K_9$ are triple linked
Creators: name: Naimi, Ramin
name: Pavelescu, Elena
Publisher: name: arXiv
Year: 2012
Subjects: subject: Geometric Topology (math.GT)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: We use the theory of oriented matroids to show that any linear embedding of $K_9$, the complete graph on nine vertices, contains a non-split link with three components.
description: 7 pages, 1 figure. An updated Mathematica program and five files containing evidence that the program works correctly are available as ancillary files associated with this article
Modulation von MRP-Transporter durch Metalle in Lungenzellen
Creators: name: Harders, Annett
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2013
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 612
subject: 610

description: Die Multidrug Resistance-Associated Proteins (MRP) stellen wichtige Transportsysteme für eine Vielzahl unterschiedlicher Substrate dar. Inwiefern As(III), Cu(II) und Hg(II) als Substrate für MRP-Transporter fungieren können und diese induzieren, wurde an der humanen Lungentumorzelllinie H322 untersucht. Um das Modellsystem bezüglich der MRP-Expression näher zu charakterisieren, ist der Einfluss unterschiedlicher Konfluenzen (80 %, 100 % und 100 % plus zusätzlichen 3 Kultivierungstagen) mit und ohne As(III), Cu(II) und Hg(II) auf die Expression der Gene MRP 1-5 und des Ubiquitously Expressed Mammalian ABC Half-Transporter (UMAT) mittels real-time RT-PCR geprüft worden. Ohne den Einfluss von Metall werden in Abhängigkeit von der Konfluenz die Gene MRP 2-5 und UMAT unterschiedlich stark moduliert. In Gegenwart von As(III) wird MRP3 bei 100 % Konfluenz induziert. Cu(II) induziert die Gene MRP4 und UMAT bei Konfluenz 100 % + 3 Tage und Hg(II) induziert MRP1 bei 100 % Konfluenz. Im Langzeitexperiment mit Hg(II) in einem Zeitraum von 28 Tagen scheint keines der untersuchten Gene am Transport von Quecksilber beteiligt zu sein. So werden die Gene MRP1-4 und UMAT nach 28 Tagen und MRP5 nach 14 Tagen mit Hg(II) signifikant reprimiert.
description: Multidrug Resistance-Associated Proteins (MRP) are important transport systems for a large number of different substrates. A possible modulation of these transporters by As(III), Cu(II) und Hg(II) was investigated in the human lung tumour cell line H322. In order to characterize the model system with respect to MRP-Expression, the influence of different confluence stages (80 %, 100 % und 100 % + 3 days) on the expression of MRP1 to 5 and the Ubiquitously Expressed Mammalian ABC half-Transporter (UMAT) with or without As(III), Cu(II) und Hg(II) was determined using real-time RT-PCR. Without the influence of metal the genes MRP2-5 and UMAT showed a varying modulation by confluence. In the presence of arsenite MRP3 is induced at 100 % confluence. Cu(II) induces the genes MRP4 and UMAT at confluence 100 % + 3 days and Hg(II) induces MRP1 at 100 % confluence. In the long-term experiment with Hg(II) during 28 days none of the tested genes seemed to be involved in transporting mercury. The influence of mercury caused a significant repression of the genes MRP1-4 and UMAT after 28 days and of the MRP5-gene after 14 days.
Embedded Network Interactive - VoXel flyer
Creators: name: Simon Vogl
name: Jutta Vogl
name: VoXel
Publisher: name: Zenodo
Year: 2023

description: The Smart Production Solutions (SPS) fair is the yearly flagship event for presenting industrial automation solutions in the DACH region, held in Nuremberg, Germany. Together with Becom Electronics GmbH which develops ToF-based 3D cameras, VoXel has been showcasing an embedded gesture recognition solution enabling hands-free interaction. Embedded platforms enabling such time-critical results in a heterogeneous industrial network environment have the requirement to be kept up to date with the latest security standards to not compromise overall system behaviour, which was another important aspect that could be highlighted. The flyer provides a short introduction to VoXel, the underlying computer vision pipeline and gesture recognition solution and was a good interaction point to discuss related security with interested parties.
Magnetic-field-induced superconductivity and superfluidity of W and Z bosons: in tandem transport and kaleidoscopic vortex states
Creators: name: Chernodub, M. N.
name: Van Doorsselaere, Jos
name: Verschelde, Henri
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We show that in a background of a sufficiently strong magnetic field the electroweak sector of the quantum vacuum exhibits superconducting and, unexpectedly, superfluid properties due to the magnetic-field-induced condensation of, respectively, W and Z bosons. The phase transition to the "tandem" superconductor-superfluid phase -- which is weakly sensitive to the Higgs sector of the standard model -- occurs at the critical magnetic field of 10^{20} T. The superconductor-superfluid phase of the electroweak vacuum has anisotropic transport properties as both charged and neutral superflows may propagate only along the magnetic field axis. The ground state possesses an unusual "kaleidoscopic" structure made of a hexagonal lattice of superfluid vortices superimposed on a triangular lattice of superconductor vortices.
description: 7 pages, 11 figures; v2: discussions extended, matches the published version
Chirurgische Versorgung primär maligner Tumoren der Niere und des Nierenbeckens anhand der DRG-Statistik der Jahre 2005 und 2006
Creators: name: Büchel, Christian
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2013
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 616
subject: 610

description: Primär maligne Tumoren der Niere machen weltweit etwa 2 % aller bösartigen Tumorerkrankungen aus. Es werden Nierenparenchymtumoren von Nierenbeckentumoren unterschieden. Standardtherapie für beide Diagnosen ist die Nephrektomie. Ziel der Arbeit ist es, unter Verwendung der bundesweiten DRG-Daten der Jahre 2005 und 2006 die chirurgische Versorgung bösartiger Nierentumore zu analysieren. Die über die DRG-Daten geschätzte altersstandardisierte Inzidenz der malignen Nierenparenchymtumoren beträgt im Bundesdurchschnitt 14,6 pro 100.000 für Männer und 7,4 für Frauen. Es zeigen sich große regionale Unterschiede mit deutlich höheren Neuerkrankungsraten in den neuen Bundesländern mit Ausnahme von Berlin. Die häufigste Operation bei malignen Nierentumoren ist die radikale offen chirurgisch lumbale Tumornephrektomie. Organerhaltende Operationen werden bei Männern in etwa 20 %, bei Frauen in etwa 16 % aller Hospitalisationen durchgeführt. Insgesamt ist bei malignen Nierentumoren in ca. 22 % aller Nephrektomien mit einer Komplikation zu rechnen, wobei der überwiegende Anteil auf Blutungen zurückzuführen ist.
description: Malignant neoplasms of the kidney account for about 2% of all new cancer cases worldwide. The two major groups of kidney tumors include renal cell carcinoma and cancers of renal pelvis. Nephrectomy is the standard therapy for both tumors. Based on the nationwide DRG statistics of Germany from 2005 to 2006, I analyzed the surgical treatment of primary malignant renal and renal pelvis neoplasms. The overall age-standardized DRG-based incidence rates of primary malignant renal neoplasms in Germany was 14.6 per 100,000 men and 7,4 per 100,000 women. Large regional incidence differences with higher rates of malignant renal neoplasms in the East German states (excluding Berlin) were observed. The most frequent surgical technique for malignant renal neoplasms is radical lumbal nephrectomy. Nephron-sparing surgery is performed in 20 % of the male and 16 % of the female patients. Overall, complications in the surgical treatment of malignant renal neoplasms occured in 22 % of all cases with mostly bleeding complications.
Extreme Value Analysis of Empirical Frame Coefficients and Implications for Denoising by Soft-Thresholding
Creators: name: Haltmeier, Markus
name: Munk, Axel
Publisher: name: arXiv
Year: 2012
Subjects: subject: Numerical Analysis (math.NA)
subject: Applications (stat.AP)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: Denoising by frame thresholding is one of the most basic and efficient methods for recovering a discrete signal or image from data that are corrupted by additive Gaussian white noise. The basic idea is to select a frame of analyzing elements that separates the data in few large coefficients due to the signal and many small coefficients mainly due to the noise ε_n. Removing all data coefficients being in magnitude below a certain threshold yields a reconstruction of the original signal. In order to properly balance the amount of noise to be removed and the relevant signal features to be kept, a precise understanding of the statistical properties of thresholding is important. For that purpose we derive the asymptotic distribution of max_{ω\in Ω_n} || for a wide class of redundant frames (ϕ_ω^n: ω\in Ω_n}. Based on our theoretical results we give a rationale for universal extreme value thresholding techniques yielding asymptotically sharp confidence regions and smoothness estimates corresponding to prescribed significance levels. The results cover many frames used in imaging and signal recovery applications, such as redundant wavelet systems, curvelet frames, or unions of bases. We show that `generically' a standard Gumbel law results as it is known from the case of orthonormal wavelet bases. However, for specific highly redundant frames other limiting laws may occur. We indeed verify that the translation invariant wavelet transform shows a different asymptotic behaviour.
description: [Content: 39 pages, 4 figures] Note that in this version 4 we have slightely changed the title of the paper and we have rewritten parts of the introduction. Except for corrected typos the other parts of the paper are the same as the original versions 1
Texture Zeros and WB Transformations in the Quark Sector of the Standard Model
Creators: name: Giraldo, Yithsbey
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Stimulated by the recent attention given to the texture zeros found in the quark mass matrices sector of the Standard Model, an analytical method for identifying (or to exclude) texture zeros models will be implemented here, starting from arbitrary quark mass matrices and making a suitable weak basis transformation, we are be able to find equivalent quark mass matrix. It is shown that the number of non-equivalent quark mass matrix representations is finite. We give exact numerical results for parallel and non-parallel four-texture zeros models. We find that some five-texture zeros Ans$\ddot{\textrm{a}}$tze are in agreement with all present experimental data. And we confirm definitely that six-texture zeros of Hermitian quark mass matrices are not viable models anymore.
description: 19 pages, version 3 corrects for typos, text minor updated, improvements in the text, numerical physical data updated
THE ROLE OF COMPUTER TECHNOLOGIES IN THE DEVELOPMENT OF EDUCATION SYSTEM
Creators: name: Bashirova Zarina Yusif
Publisher: name: Endless light in science
Year: 2023
Subjects: Computer
technology
education system
student
pedagogue
electronic.

description: Computer technologies pave the way for the usage of new methods, forms and means in education, the formation of children as an individual and the determination and development of his (her) hidden and obvious skills. It has been identified that children receive 70-80% of information from their parents and observations of life around them, mass media and social networks. There is a higher probability of children to obtain harmful information from social networks. Therefore, to control their use of the Internet and computer programs in beneficial ways is necessary. This is the responsibility of both parents and educational institutions. Thus, the application of computer technologies in education is one of the topical problems of the modern time. The paper deals with the role of computer technologies in the development of education system
Additional file 1: of Gas Sensors Based on Chemically Reduced Holey Graphene Oxide Thin Films
Creators: name: Yang, Ming
name: Wang, Yanyan
name: Dong, Lei
name: Xu, Zhiyong
name: Liu, Yanhua
name: Hu, Nantao
name: Kong, Eric
name: Zhao, Jiang
name: Peng, Changsi
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Figure S1. An enlarged AFM image of GO sheets after reaction with Fenton reagent under UV irradiation for 1â h. Figure S2. AFM image (a) and height profile (b) of GO sheets before reaction with Fenton reagent. Figure S3. The ID/IG distribution of Raman test for rHGO thin-film: 20 different locations were tested on the same sample. Figure S4. The resistance distribution of 50 rHGO thin-film gas sensors. (DOC 14183 kb)
The K-process on a tree as a scaling limit of the GREM-like trap model
Creators: name: Fontes, L. R. G.
name: Gava, R. J.
name: Gayrard, V.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: We introduce trap models on a finite volume $k$-level tree as a class of Markov jump processes with state space the leaves of that tree. They serve to describe the GREM-like trap model of Sasaki and Nemoto. Under suitable conditions on the parameters of the trap model, we establish its infinite volume limit, given by what we call a $K$-process in an infinite $k$-level tree. From this we deduce that the $K$-process also is the scaling limit of the GREM-like trap model on extreme time scales under a fine tuning assumption on the volumes.
description: Published in at http://dx.doi.org/10.1214/13-AAP937 the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org)
INVESTIGATING OFFENDER TYPOLOGIES AND VICTIM VULNERABILITIES IN ONLINE CHILD GROOMING
Creators: name: Simhadri, Siva sahitya
Publisher: name: Purdue University Graduate School
Year: 2023
Subjects: classificationCode: 460501
subject: Data engineering and data science
classificationCode: 490599
subject: Statistics not elsewhere classified

description: One of the issues on social media that is expanding the fastest is children being exposed to predators online [ 1 ]. Due to the ease with which a larger segment of the younger population may now access the Internet, online grooming activity on social media has grown to be a significant social concern. Child grooming, in which adults and minors exchange sexually explicit text and media via social media platforms, is a typical component of online child exploitation. An estimated 500,000 predators operate online every day. According to estimates, Internet chat rooms and instant messaging are where 89% of sexual approaches against children take place. The child may face a variety of unpleasant consequences following a grooming event, including shame, anger, anxiety, tension, despair, and substance abuse which make it more difficult for them to report the exploitation. A substantial amount of research in this domain has focused on identifying certain vulnerabilities of the victims of grooming. These vulnerabilities include specific age groups, gender, psychological factors, no family support, and lack of good social relations which make young people more vulnerable to grooming. So far no technical work has been done to apply statistical analysis on these vulnerability profiles and observe how these patterns change between different victim types and offender types. This work presents a detailed analysis of the effect of Offender type (contact and fantasy) and victim type (Law Enforcement Officers, Real Victims and Decoys (Perverted Justice)) on representation of different vulnerabilities in grooming conversations. Comparison of different victim groups would provide insights into creating the right training material for LEOs and decoys and help in the training process for online sting operations. Moreover, comparison of different offender types would help create targeted prevention strategies to tackle online child grooming and help the victims.
Detektion des Pro-Nerve Growth Factor (ProNGF) an der Augenoberfläche und im Tränenapparat im Vergleich mit der maturen Form NGF
Creators: name: Peters, Johannes Hubertus
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2012
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 611

description: NGF gehört zu den Neurotrophinen. Diese sollen Wachstum, Differenzierung und Überleben bestimmter Nervenzellen vermitteln. Im Gegensatz zum reifen NGF ist die Vorstufe, ProNGF, posttranslational noch nicht prozessiert. ProNGF soll an der Induktion der Apoptose beteiligt sein. Beide Formen wurden bisher in Geweben, wie Plazenta, Haut oder Kolon nachgewiesen. Ziel ist es, die Proteinformen von NGF und ProNGF jeweils in Tränendrüse, Konjunktiva, Cornea und ableitenden Tränenwegen, sowie für NGF gesondert in konjuntivalen und cornealen Zelllinien nachzuweisen. Es wird Gewebe von Körperspendern sowie immortalisierte Zellen untersucht. NGF ist in allen untersuchten Geweben und in cornealen Epithelzellen der Epithelzellen mindestens mit einer der durchgeführten Methoden, nachweisbar. ProNGF konnte auf Proteinebene in Gewebe von Cornea, Konjuktiva, Tränendrüse und Tränenweg nachgewiesen werden. Zukünftig gilt es herauszufinden, wie die Konzentrationsverteilung und Regulation der Faktoren in den jeweiligen Geweben ist. Hieraus könnte ein therapeutischer Nutzen erwachsen.
description: NGF is one of the neurotrophins. This will give growth, differentiation and survival of certain nerve cells. Contrary to the precursor mature NGF, proNGF is not posttranslationally processed. ProNGF to be involved in the induction of apoptosis. Both forms have been detected in tissues such as placenta, skin or colon. The aim is the protein forms of NGF and ProNGF each in lacrimal gland, conjunctiva, cornea and lacrimal drainage paths, and for NGF separately detected in konjuntivalen and corneal cell lines. It is examined tissues of the body donors and immortalized cells. NGF is present in all tissues examined, and corneal epithelial cells in the epithelial cells with at least one of the methods implemented detectable. ProNGF was detected at the protein level in tissue of cornea, conjunctiva, lacrimal gland and tear duct. In the future it is to find out how the concentration distribution and regulation of the factors in the respective tissues. From this, a therapeutic benefit could accrue.
Quantum Computation with Coherent Spin States and the Close Hadamard Problem
Creators: name: Adcock, Mark
name: Hoyer, Peter
name: Sanders, Barry C.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study a model of quantum computation based on the continuously-parameterized yet finite-dimensional Hilbert space of a spin system. We explore the computational powers of this model by analyzing a pilot problem we refer to as the close Hadamard problem. We prove that the close Hadamard problem can be solved in the spin system model with arbitrarily small error probability in a constant number of oracle queries. We conclude that this model of quantum computation is suitable for solving certain types of problems. The model is effective for problems where symmetries between the structure of the information associated with the problem and the structure of the unitary operators employed in the quantum algorithm can be exploited.
description: RevTeX4, 13 pages with 8 figures. Accepted for publication in Quantum Information Processing. Article number: s11128-015-1229-0
Humane Surfactant Proteine - Detektion und Charakterisierung
Creators: name: Schicht, Martin
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2012
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 572
subject: 610

description: In der vorliegenden Arbeit konnte gezeigt werden, dass verschiedene Stämme von S. aureus und P. aeruginosa Proteine exprimieren und sekretieren, die mit kommerziell verfügbaren Antikörpern reagieren, welche gegen humane Surfactant Proteine gerichtet sind. Die Ergebnisse spiegeln möglicherweise die Existenz einer neuen Gruppe bakterieller Proteine wieder, die momentan in den jeweiligen Sequenz und Struktur Datenbanken fehlen. Durch die Anwesenheit dieser bakteriellen Proteine könnten immunologische und molekularbiologische Untersuchungen verfälscht worden sein, woraus sich eine kritische Neubewertung der bisherigen Ergebnisse ergeben sollte. Ein weiterer Teil befasst sich die Arbeit mit der Erstbeschreibung und Charakterisierung von zwei neuen, unbeschriebenen Proteinen, die eine neue Klasse von Surfactant Proteinen darstellen könnten und als SP-G bzw. SP-H bezeichnet werden. In einem weiteren Schwerpunkt konnte die Surfactant Proteine in den Zellen des humanen Gelenkknorpels nachgewiesen werden. Diese Ergebnisse lassen vermuten, dass die bekannten Surfactant Proteine (A, B, C und D) von menschlichen Knorpelzellen gebildet werden und offensichtlich funktionell wichtig sind.
description: Within this work it could be shown that different strains of S. aureus and P. aeruginosa express and secrete proteins that react with commercially available antibodies against human surfactant proteins. The results suggest that the bacteria are either able to express ‘human-like’ surfactant proteins on their own or that commercially available antibodies against human surfactant proteins detect identical bacterial proteins. The results may reflect the existence of a new group of bacterial surfactant proteins currently lacking in the relevant sequence and structure databases. At any rate, our knowledge of human surfactant proteins obtained from immunological and molecular biological studies may have been falsified by the presence of bacterial proteins and DNA and therefore requires critical reassessment. Another part demonstrated the description and characterization of two new unknown proteins for the first time. Both proteins, named SP-G and SP-H, may represent a new class of surfactant proteins. Furthermore, experiments showed for the first time that chondrocytes of human cartilage express human surfactant proteins. The results suggest that the surfactant proteins (A, B, C and D) are important and functionally significant components of human cartilage.
Retrospective Harmonisation of the KULT Slovak Cultural Surveys
Creators: name: Antal, Daniel
Publisher: name: Zenodo
Year: 2023
Subjects: Slovakia
Survey harmonisation
R programming language

description: We use the KULT summary documents to re-create the necessary metadata of the KULT microdata files and to create checkpoints. These PDF files contain the Slovak variable labels for each survey's module and columns and the sum of numeric values, which will be used as checksums when we read the raw data into R.
The Open Music Europe project aims to become a data producer or co-producer using novel statistical methods that combine governmental data with privately held (music industry) data (See our Memorandum of Understanding (Ministerstvo kultúry SR and Open Music Europe 2023) and the more detailed statistical program (Antal 2023a).) Our most immediate target for harmonisation is the KULT (enterprise or institutional surveys). To suggest beneficial and easy-to-implement, forward-looking, ex-ante modifications, we first need to carry out a retrospective or ex-post analysis to understand the data's opportunities and weaknesses better.
Analysis of nutritional patterns in individuals at risk for the development of the metabolic syndrome assessed by a food frequency questionnaire
Creators: name: Frisch, Annett
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2013
Subjects: subject: Ernährungsphysiologie
subject: Geschlechtsunterschied
subject: Online-Publikation
subject: Hochschulschrift
subject: 610

description: Hintergrund: Ziel dieser Studie war es, die Nährstoff- und Lebensmittelaufnahme sowie die Assoziation dieser Nahrungsaufnahme mit der Entwicklung des Metabolischen Syndroms zu beschreiben. Methodik: Mit Hilfe eines selbstauszufüllenden semiquantitativen Verzehrshäufigkeitenfragebogens wurde die Nahrungsaufnahme von 1962 Probanden der Lipid and Glucose under prospective surveillance Studie erfasst. Energie- und Nährstoffaufnahme, Ernährungsmuster, die Einnahme von Nahrungsergänzungsmitteln, Süßstoffen und diätetischen Lebensmitteln wurden getrennt für Männer und Frauen sowie für verschiedene Altersgruppen ausgewertet. Ergebnisse: Insgesamt verzehrten junge Männer größere Mengen Fleisch, Weißmehlprodukte und fettreiche Milchprodukte. Männer und Frauen in den höheren Altersklassen verzehrten mehr Fisch, Obst, Gemüse, Nüsse, Samen, Vollkornprodukte und Tee. Die Einnahme von Nahrungsergänzungsmitteln, Süßstoffen und diätetischen Lebensmitteln war bei den Frauen höher als bei Männern. Schlussfolgerungen: Die Studie zeigt ein protektives Ernährungsmuster für Frauen und einen insgesamt höheren Verzehr günstiger Lebensmittel bei älteren Studienteilnehmern.
description: Background: This study aimed to describe the food and nutrient intake of healthy individuals and to evaluate the relation of the dietary patterns with the development of the metabolic syndrome. Methods: Usual dietary patterns were assessed in the Lipid and Glucose under prospective surveillance of 1.962 individuals by a self-administered semi quantitative food frequency questionnaire. Energy, nutrient intakes, food patterns, the use of supplements, artificial sweeteners, sugar substitutes and dietetic foods were calculated stratified by gender and age. Results: In young men, we identified food patterns dominated by meat, refined grains and high-fat dairy products. Food pattern for men and women at higher age showed highest intakes of fish, fruits, vegetables, nuts, seeds, wholemeal products and tea. Overall reported use of supplements, artificial sweeteners, sugar substitutes, dietetic foods was higher in women than in men. Conclusions: The study shows a protective dietary pattern for women and higher intakes of desirable foods in the elderly.