cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Perioperatiivne süvaveenitromboosi profülaktika
Creators: name: Sell, Andres
Publisher: name: Eesti Arst
Year: 2010
Subjects: veenitromboos, antikoagulantravi, tromboosiprofülaktika

description: Süvaveenitromboos on kirurgiliste operatsioonide sage tüsistus, olles eriti sage ortopeediliste operatsioonide korral. Adekvaatset perioperatiivset tromboosi profülaktikat rakendades on võimalik oluliselt nende tüsistuste sagedust vähendada. Hüübimist mõjutavate preparaatide (hepariin, fondapariinuks, varfariin) kasutamine operatsiooni eel on tõhus trombembooliliste tüsistuste ärahoidmisel, ilma et suureneks hemorraagiliste tüsistuste esinemissagedus.

  Eesti Arst 2010; 89(2):127−131
description: Eesti Arst, Veebruar 2010
Kaelavaluga haige käsitluse põhimõtted
Creators: name: Vaher, Ando
name: Sinisalu, Väino
Publisher: name: Eesti Arst
Year: 2010
Subjects: kaelavalu, kaelaradikulopaatia, nn whiplash-sündroom, mittesteroidsed põletikuvastased ained

description: Kaelavalu on levinud tervisehäire. Need haiged on perearstide, närviarstide, ortopeedide, reumatoloogide sagedased külastajad. Enamasti on tegemist hea prognoosiga, sageli iseparaneva mittespetsiifilise kaelavalu või kaelakangusega. Nii äge kui ka krooniline kaelavalu võib olla ka ohtliku halva prognoosiga haiguse sümptomiks. Need seisundid on vaja õigel ajal diagnoosida ja ravida vastava spetsialisti poolt. Valuga kaelas võib kaasneda ka radikulopaatia sümptomaatika. Kõikidel juhtudel, eriti retsidiveeruva, alaägeda ja kroonilise kulu korral on vaja täpsustada vaevuste põhjus. Visualiseerimismeetoditest on eelistatuim MRT. Kaela- ja õlavaluga haige ravi on kompleksne (füsiaatriline ja medikamentoosne). Tähtsal kohal on haige nõustamine, tema aktiivne osavõtt raviprotsessist. Kirurgiline ravi on rakendatav kindlatel näidustustel. Mittespetsiifilise kaelavalu ravis (sh kaelakangus) on esmasteks meetmeteks tavapärase aktiivsuse säilitamine ja adekvaatne valuravi.´

  Eesti Arst 2010; 89(2):121−125
description: Eesti Arst, Veebruar 2010
Additional file 1 of Assessment of fetal intraventricular diastolic fluid dynamics using ultrasound vector flow mapping
Creators: name: Shu, Qinglan
name: Wang, Yi
name: Lin, Xinyi
name: Xie, Shenghua
name: Wang, Zhengyang
name: Wang, Sijia
name: Yin, Lixue
Publisher: name: figshare
Year: 2023
Subjects: Biophysics
Space Science
Medicine
Cell Biology
Molecular Biology
Biological Sciences not elsewhere classified

description: Supplementary Material 1
title: Molecular-level characterization of supraglacial dissolved and water-extractable organic matter along a hydrological flow path in a Greenland Ice Sheet micro-catchment
Creators: name: Doting, Eva L.
name: Stevens, Ian T.
name: Kellerman, Anne M.
name: Rossel, Pamela E.
name: Antony, Runa
name: McKenna, Amy M.
name: Tranter, Martyn
name: Benning, Liane G.
name: Spencer, Robert G. M.
name: Hawkings, Jon R.
name: Anesio, Alexandre M.
Publisher: name: Freie Universität Berlin
Year: 2025
Subjects: subject: Greenland Ice Sheet
subject: dissolved organic matter
subject: meltwater
classificationCode: 550
subject: Geowissenschaften

description: Sunlight penetrates the bare-ice surface of glaciers and ice sheets, giving rise to the presence of a three-dimensional porous matrix of partially melted ice crystals known as the weathering crust. Surface meltwater slowly percolates through this weathering crust, which hosts active and diverse bacterial communities, until it reaches a supraglacial stream. Despite the potential implications of weathering crust dynamics for glacial melting and the export of carbon and nutrients to downstream ecosystems, its role in biogeochemical cycling remains unknown. Here, we use Fourier transform cyclotron resonance mass spectrometry to characterize dissolved organic matter (DOM) along a meltwater flow path in a hydrologically connected micro-catchment on the southern Greenland Ice Sheet. We find a decrease in the relative abundance of aromatic formulae from surface ice (24.9 ±2.8 %) to weathering crust meltwater (3.5 ±0.3 %) to supraglacial stream water (2.2 ±0.2 %), pointing towards photodegradation of aromatic DOM during supraglacial meltwater transit. The relative abundance of aliphatic and peptide-like formulae in supraglacial stream DOM was lower (38.5 ±4.0 %) than in weathering crust meltwater DOM (50.3 ±2.4 %), likely as a result of microbial respiration of labile compounds within the weathering crust. Hence, we conclude that the weathering crust plays a thus far unexplored role in supraglacial biogeochemical cycling. In addition, we characterize water-extractable organic matter isolated from surface ice particulate matter, which was predominantly (61.6 ±8.1 % relative abundance) comprised of aliphatic and peptide-like formulae, providing the first direct evidence of surface ice particulate matter as a potential source of biolabile DOM. As the spatial extent of bare-ice surfaces and the associated weathering crust photic zone is set to increase under a warming climate, our findings underscore the pressing need to further evaluate the role of the weathering crust in supraglacial biogeochemical processes. An understanding of weathering crust biogeochemical cycling is especially critical as climatic warming is predicted to lead to an increase in Arctic rainfall, consequently increasing the frequency of weathering crust degradation events, with unknown impacts on the export of supraglacial DOM to downstream ecosystems.
title: Li/MgO with spin sensors as catalyst for the oxidative coupling of methane
Creators: name: Simon, U.
name: Arndt, S.
name: Otremba, T.
name: Schlingmann, T.
name: Görke, O.
name: Dinse, Klaus-Peter
name: Schomäcker, R.
name: Schubert, H.
Publisher: name: Freie Universität Berlin
Year: 2012
Subjects: subject: Oxidative coupling of methane
subject: Li/MgO
subject: Transition metal oxides
subject: Cation substitution
subject: Spin sensor
subject: EPR
classificationCode: 530
subject: Physik

description: Co-doping of Li/MgO, a well-known catalyst for the oxidative coupling of methane, was investigated. It is demonstrated that Gd3+ and Fe3+ can be used as spin sensors in these solids to investigate the structure via EPR spectroscopy. These aliovalent ions occupy Mg2+ sites in the lattice; the expected coupling with charge-compensating neighboring Li+ was detected. A strong increase of the activity was observed. However, all samples suffered from deactivation. The solubility of Gd3+ in MgO turned out to be inhibited. No such restriction was observed for Fe3+.
Bupropioonravi depressiooni korral: mono- ja kombinatsioonteraapia
Creators: name: Maron, Eduard
name: Eller, Triin
name: Vasar, Veiko
Publisher: name: Eesti Arst
Year: 2010
Subjects: bupropioon, antidepressant, depressioon

description: Bupropioon on ainus dopamiini ning noradrenaliini tagasihaarde inhibiitor, mis on näidustatud depressiivse häire ja aastaajast sõltuva meeleoluhäire raviks, olles kliiniliste uuringute põhjal niisama tõhus kui teised antidepressandid. Kakskümmend aastat kliinilist praktikat kinnitab bupropiooni ohutust ning efektiivsust, seega on ta kasutatav esimese valiku preparaadina. Üha enam tõendeid räägib ka bupropiooni kasutamise poolt juhtudel, kui depressiivne sümptomaatika serotoniini tagasihaarde inhibiitorite abil ei taandu või taandub vaid osaliselt. Mitmed uuringud kinnitavad bupropiooni eeliseid serotoninergiliste antidepressantide ees melanhoolsete sümptomite ravis. Ülevaates on keskendutud bupropioonravi eelistele depressiivsete patsientide ravis, et optimeerida selle kasutamist arstlikus praktikas.

  Eesti Arst 2010; 89(2):113−119
description: Eesti Arst, Veebruar 2010
title: Inhibition of a Secreted Immune Molecule Interferes With Termite Social Immunity
Creators: name: Esparza Mora, Margy Alejandra
name: Davis, Hannah E.
name: Meconcelli, Stefania
name: Plarre, Rudy
name: McMahon, Dino P.
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: termite
subject: social immunity
subject: cannibalism
subject: hygienic behavior
subject: GNBP-2
subject: GDL
subject: Metarhizium
subject: entomopathogen
classificationCode: 570
subject: Biowissenschaften; Biologie

description: Social immune behaviors are described in a great variety of insect societies and their role in preventing emerging infectious diseases has become a major topic in insect research. The social immune system consists of multiple layers, ranging from the synthesis of external immune molecules to the coordination of individual behaviors into sophisticated collective defensive tasks. But our understanding of how complex group-level behavioral defenses are orchestrated has remained limited. We sought to address this gap in knowledge by investigating the relationship between the external activity of an important immune effector molecule in termites, Gram negative binding protein 2 (GNBP-2) and collective grooming and cannibalism. We reasoned that as an external enzyme capable of degrading entomopathogenic fungi, GNBP-2 can facilitate the spread of pathogenic molecules in the colony, and thus serve to trigger collective defenses in a manner analogous to pathogen-associated molecular signatures (PAMPs) of the individual immune system. To test whether GNBP-2 could play a role in regulating social immune behavior, we experimentally inhibited its fungicidal activity using the glycomimetic molecule, D-d-gluconolactone (GDL) and recorded collective behavioral responses to an infected nestmate. Contrary to expectations, GNBP-2 inhibition did not influence the rate or intensity of grooming of either control or fungus-infected nestmates. By contrast, we found that the probability of being harmed through defensive cannibalistic behaviors was significantly reduced by the inhibition of GNBP-2. Our findings indicate that the regulation of collective immune behaviors may depend in part on the external secretion of an enzyme originating from the individual immune system, but that other cues are also necessary.
Aspergilloos ninakõrvalurgetes
Creators: name: Lieberg, Neve
name: Müürsepp, Peeter
name: Murde, Maret
Publisher: name: Eesti Arst
Year: 2010
Subjects: aspergilloos, ninakõrvalurked, diagnoos, ravi

description: Aspergilloos on kõige sagedasem sinonasaalne seeninfektsioon. Haigus võib kulgeda invasiivse või mitteinvasiivse vormina. Haigestuvad tavaliselt eelnevalt nõrgenenud immuunsusega inimesed. Sagedasim haigustekitaja on Aspergillus fumigatus. Infektsiooni diagnoosi kinnitab siinuse koetüki või aspiraadi patohistoloogilise uuringu positiivne vastus. Mitteinvasiivse aspergilloosi ravi kuldstandardiks on FESS (funktsionaalne endoskoopiline siinuste operatsioon), invasiivne aspergilloos nõuab radikaalsemat kirurgilist sekkumist ja süsteemset antifungaal set ravi. Artiklis on ka illustratiivne ülevaade kroonilise sinuiidi ja aspergilloosiga meespatsiendi haigusjuhust.

  Eesti Arst 2010; 89(2):107−112
description: Eesti Arst, Veebruar 2010
Additional file 1 of Prognostic value of fibrosis-5 index combined with C-reactive protein in patients with acute decompensated heart failure
Creators: name: Wang, Ziyan
name: Li, Guannan
name: Huang, Rong
name: Chang, Lei
name: Gong, Chenyi
name: Chen, Ke
name: Wang, Lian
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Hematology
subject: Virology

description: Supplementary Material 1
title: A change in coral extension rates and stable isotopes after El Niño-induced coral bleaching and regional stress events
Creators: name: Hetzinger, S.
name: Pfeiffer, M.
name: Dullo, W.-C.
name: Zinke, J.
name: Garbe-Schoenberg, D.
Publisher: name: Freie Universität Berlin
Year: 2016
Subjects: subject: Environmental impact
subject: Marine biology
subject: Palaeoceanography
subject: Palaeoclimate
subject: Stable isotope analysis
classificationCode: 550
subject: Geowissenschaften, Geologie

description: Coral reefs are biologically diverse ecosystems threatened with effective collapse under rapid climate change, in particular by recent increases in ocean temperatures. Coral bleaching has occurred during major El Niño warming events, at times leading to the die-off of entire coral reefs. Here we present records of stable isotopic composition, Sr/Ca ratios and extension rate (1940–2004) in coral aragonite from a northern Venezuelan site, where reefs were strongly impacted by bleaching following the 1997–98 El Niño. We assess the impact of past warming events on coral extension rates and geochemical proxies. A marked decrease in coral (Pseudodiploria strigosa) extension rates coincides with a baseline shift to more negative values in oxygen and carbon isotopic composition after 1997–98, while a neighboring coral (Siderastrea siderea) recovered to pre-bleaching extension rates simultaneously. However, other stressors, besides high temperature, might also have influenced coral physiology and geochemistry. Coastal Venezuelan reefs were exposed to a series of extreme environmental fluctuations since the mid-1990s, i.e. upwelling, extreme rainfall and sediment input from landslides. This work provides important new data on the potential impacts of multiple regional stress events on coral isotopic compositions and raises questions about the long-term influence on coral-based paleoclimate reconstructions.
Regionaalhaigla X-korpus – samm uude sajandisse
Creators: name: Lill, Inga
Publisher: name: Eesti Arst
Year: 2010

description: Põhja-Eesti Regionaalhaigla avas eelmise aasta 11. detsembril Mustamäe meditsiinilinnakus haigla uue korpuse. See on innovaati line diagnostikaja aktiivravikompleks, kus hakkab toimuma kõige tehnoloogiamahukam osa ravitööst.

  Eesti Arst 2010; 89(1):67−68
description: Eesti Arst, Jaanuar 2010
Additional file 4 of Assessment and management of chronic insomnia disorder: an algorithm for primary care physicians
Creators: name: Selsick, Hugh
name: Heidbreder, Anna
name: Ellis, Jason
name: Ferini-Strambi, Luigi
name: García-Borreguero, Diego
name: Leontiou, Chrysoula
name: Mak, Michael S.B.
name: O’Regan, David
name: Parrino, Liborio
Publisher: name: figshare
Year: 2024
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Mental Health
subject: Hematology

description: Supplementary Material 4
title: Catalytic oxygenation of sp3 “C-H” bonds with Ir(III) complexes of chelating triazoles and mesoionic carbenes
Creators: name: Hohloch, Stephan
name: Kaiser, Selina
name: Duecker, Fenja Leena
name: Bolje, Aljoša
name: Maity, Ramananda
name: Košmrlj, Janez
name: Sarkar, Biprajit
Publisher: name: Freie Universität Berlin
Year: 2015
Subjects: classificationCode: 540
subject: Chemie

description: Cp*-Ir(III) complexes with additional chelating ligands are known active pre- catalysts for the oxygenation of C–H bonds. We present here eight examples of such complexes where the denticity of the chelating ligands has been varied from the well-known 2,2′-bpy through pyridyl-triazole, bi-triazole to ligands containing pyridyl-triazolylidene, triazolyl-triazolylidene and bi- triazolylidenes. Additionally, we also compare the catalytic results to complexes containing chelating cyclometallated ligands with additional triazole or triazolylidene donors. Single crystal X-ray structural data are presented for all the new complexes that contain one or more triazolylidene donors of the mesoionic carbene type. We present the first example of a metal complex containing a chelating triazole-triazolylidene ligand. The results of the catalytic screening show that complexes containing unsymmetrical donors of the pyridyl-triazole or pyridyl-triazolylidene types are the most potent pre- catalysts for the C–H oxygenation of cyclooctane in the presence of either m-CPBA or NaIO4 as a sacrificial oxidant. These pre-catalysts can also be used to oxygenate C–H bonds in other substrates such as fluorene and ethyl benzene. The most potent pre-catalysts presented here work with a lower catalyst loading and under milder conditions while delivering better product yields in comparison with related literature known Ir(III) pre-catalysts. These results thus point to the potential of ligands with unsymmetrical donors obtained through the click reaction in oxidation catalysis.
sj-doc-3-jvm-10.1177_13567667211063206 - Supplemental material for Rio 2016 Olympic Games: Brand and the reciprocal effects of touristic destinations
Creators: name: Ferreira, Luciana Brandão
name: Giraldi, Janaina de Moura Engracia
name: Santos, Glauber Eduardo de Oliveira
name: Jabbour, Charbel Jose Chiappetta
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 150402 Hospitality Management

description: Supplemental material, sj-doc-3-jvm-10.1177_13567667211063206 for Rio 2016 Olympic Games: Brand and the reciprocal effects of touristic destinations by Luciana Brandão Ferreira, Janaina de Moura Engracia Giraldi, Glauber Eduardo de Oliveira Santos and Charbel Jose Chiappetta Jabbour in Journal of Vacation Marketing
Additional file 1 of Prevalence of, association with, severity of, and prognostic role of serum hemoglobin level in acutely decompensated heart failure patients
Creators: name: Omoomi, Sepehr
name: Heidarpour, Maryam
name: Rabanipour, Najmeh
name: Saadati, Mona
name: Vakilbashi, Omid
name: Shafie, Davood
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Computational Biology

description: Supplementary Material 1
title: Local and systemic effect of transfection-reagent formulated DNA vectors on equine melanoma
Creators: name: Mählmann, Kathrin
name: Feige, Karsten
name: Juhls, Christiane
name: Endmann, Anne
name: Schuberth, Hans-Joachim
name: Oswald, Detlef
name: Hellige, Mareu
name: Doherr, Marcus G.
name: Cavalleri, Jessika
Publisher: name: Freie Universität Berlin
Year: 2015
Subjects: subject: Horse
subject: Melanoma
subject: Interleukin
subject: Glycoprotein 100
subject: Tyrosinase
subject: DNA vaccine
classificationCode: 630
subject: Landwirtschaft

description: Background Equine melanoma has a high incidence in grey horses. Xenogenic DNA vaccination may represent a promising therapeutic approach against equine melanoma as it successfully induced an immunological response in other species suffering from melanoma and in healthy horses. In a clinical study, twenty- seven, grey, melanoma-bearing, horses were assigned to three groups (n = 9) and vaccinated on days 1, 22, and 78 with DNA vectors encoding for equine (eq) IL-12 and IL-18 alone or in combination with either human glycoprotein (hgp) 100 or human tyrosinase (htyr). Horses were vaccinated intramuscularly, and one selected melanoma was locally treated by intradermal peritumoral injection. Prior to each injection and on day 120, the sizes of up to nine melanoma lesions per horse were measured by caliper and ultrasound. Specific serum antibodies against hgp100 and htyr were measured using cell based flow- cytometric assays. An Analysis of Variance (ANOVA) for repeated measurements was performed to identify statistically significant influences on the relative tumor volume. For post-hoc testing a Tukey-Kramer Multiple-Comparison Test was performed to compare the relative volumes on the different examination days. An ANOVA for repeated measurements was performed to analyse changes in body temperature over time. A one-way ANOVA was used to evaluate differences in body temperature between the groups. A p–value < 0.05 was considered significant for all statistical tests applied. Results In all groups, the relative tumor volume decreased significantly to 79.1 ± 26.91% by day 120 (p < 0.0001, Tukey-Kramer Multiple-Comparison Test). Affiliation to treatment group, local treatment and examination modality had no significant influence on the results (ANOVA for repeated measurements). Neither a cellular nor a humoral immune response directed against htyr or hgp100 was detected. Horses had an increased body temperature on the day after vaccination. Conclusions This is the first clinical report on a systemic effect against equine melanoma following treatment with DNA vectors encoding eqIL12 and eqIL18 and formulated with a transfection reagent. Addition of DNA vectors encoding hgp100 respectively htyr did not potentiate this effect.
Additional file 5 of Assessment and management of chronic insomnia disorder: an algorithm for primary care physicians
Creators: name: Selsick, Hugh
name: Heidbreder, Anna
name: Ellis, Jason
name: Ferini-Strambi, Luigi
name: García-Borreguero, Diego
name: Leontiou, Chrysoula
name: Mak, Michael S.B.
name: O’Regan, David
name: Parrino, Liborio
Publisher: name: figshare
Year: 2024
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Mental Health
subject: Hematology

description: Supplementary Material 5
title: Open-system dynamics of entanglement:a key issues review
Creators: name: Aolita, Leandro
name: Melo, Fernando De
name: Davidovich, Luiz
Publisher: name: Freie Universität Berlin
Year: 2015
Subjects: classificationCode: 530
subject: Physik

description: One of the greatest challenges in the fields of quantum information processing and quantum technologies is the detailed coherent control over each and every constituent of quantum systems with an ever increasing number of particles. Within this endeavor, harnessing of many-body entanglement against the detrimental effects of the environment is a major pressing issue. Besides being an important concept from a fundamental standpoint, entanglement has been recognized as a crucial resource for quantum speed-ups or performance enhancements over classical methods. Understanding and controlling many-body entanglement in open systems may have strong implications in quantum computing, quantum simulations of many-body systems, secure quantum communication or cryptography, quantum metrology, our understanding of the quantum-to-classical transition, and other important questions of quantum foundations. In this paper we present an overview of recent theoretical and experimental efforts to underpin the dynamics of entanglement under the influence of noise. Entanglement is thus taken as a dynamic quantity on its own, and we survey how it evolves due to the unavoidable interaction of the entangled system with its surroundings. We analyze several scenarios, corresponding to different families of states and environments, which render a very rich diversity of dynamical behaviors. In contrast to single-particle quantities, like populations and coherences, which typically vanish only asymptotically in time, entanglement may disappear at a finite time. In addition, important classes of entanglement display an exponential decay with the number of particles when subject to local noise, which poses yet another threat to the already-challenging scaling of quantum technologies. Other classes, however, turn out to be extremely robust against local noise. Theoretical results and recent experiments regarding the difference between local and global decoherence are summarized. Control and robustness- enhancement techniques, scaling laws, statistical and geometrical aspects of multipartite-entanglement decay are also reviewed; all in order to give a broad picture of entanglement dynamics in open quantum systems addressed to both theorists and experimentalists inside and outside the field of quantum information.
Additional file 1 of The effect of PD-1/PD-L1 signaling axis on the interaction between CD19+B cells and CD4+T cells in peripheral blood of patients with systemic lupus erythematosus
Creators: name: Xie, Zhuobei
name: Dai, Li
name: He, Haohua
name: Hong, Dengxiao
name: Tang, Honghui
name: Xu, Wenyan
name: Chen, Zhongxin
name: Wang, Hongtao
name: Li, Baiqing
name: Xie, Changhao
name: Wang, Yuanyuan
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Supplementary Material 1
title: Circadian rhythms have significant effects on leaf-to-canopy scale gas exchange under field conditions
Creators: name: Resco De Dios, Victor
name: Gessler, Arthur
name: Pedro Ferrio, Juan
name: Alday, Josu G.
name: Bahn, Michael
name: Castillo, Jorge Del
name: Devidal, Sebastien
name: Garcia-Munoz, Sonia
name: Kayler, Zachary
name: Landais, Damien
name: Martin-Gomez, Paula
name: Milcu, Alexandru
name: Piel, Clement
name: Pirhofer-Walzl, Karin
name: Ravel, Olivier
name: Salekin, Serajis
name: Tissue, David T.
name: Tjoelker, Mark G.
name: Voltas, Jordi
name: Roy, Jacques
Publisher: name: Freie Universität Berlin
Year: 2016
Subjects: subject: Circadian clock
subject: Ecological memory
subject: Net ecosystem exchange
subject: Scaling
subject: Stomatal conductance models
subject: Photosynthesis
subject: Transpiration
classificationCode: 570
subject: Biowissenschaften; Biologie

description: Background Molecular clocks drive oscillations in leaf photosynthesis, stomatal conductance, and other cell and leaf-level processes over ~24 h under controlled laboratory conditions. The influence of such circadian regulation over whole-canopy fluxes remains uncertain; diurnal CO2 and H2O vapor flux dynamics in the field are currently interpreted as resulting almost exclusively from direct physiological responses to variations in light, temperature and other environmental factors. We tested whether circadian regulation would affect plant and canopy gas exchange at the Montpellier European Ecotron. Canopy and leaf-level fluxes were constantly monitored under field-like environmental conditions, and under constant environmental conditions (no variation in temperature, radiation, or other environmental cues). Results We show direct experimental evidence at canopy scales of the circadian regulation of daytime gas exchange: 20–79 % of the daily variation range in CO2 and H2O fluxes occurred under circadian entrainment in canopies of an annual herb (bean) and of a perennial shrub (cotton). We also observed that considering circadian regulation improved performance by 8–17 % in commonly used stomatal conductance models. Conclusions Our results show that circadian controls affect diurnal CO2 and H2O flux patterns in entire canopies in field-like conditions, and its consideration significantly improves model performance. Circadian controls act as a ‘memory’ of the past conditions experienced by the plant, which synchronizes metabolism across entire plant canopies.
Aparsen D43.2 - Report On Launch Of Digital Preservation Training Portal For Vcoe
Creators: name: Jäschke, Gerald
name: Lambert, Simon
name: Giaretta, David
name: Kirnn Kaur
name: McMeekin, Sharon
name: Smit, Eefke
name: Becker, Jana
name: Weigl, Elisabeth
Publisher: name: Zenodo
Year: 2014
Subjects: Qualification, training, Online Training Portal (OTP)

description: This document reports on the customization, set-up and launch of the Online Training Portal (OTP). It describes the underlying specification rationale, dedicated to be of help to anyone interested in gaining initial skills or improving competence in Digital Preservation (DP). It describes the resulting online application and procedures for continuing maintenance organised by a Virtual Centre of Excellence. The addendum section reports about the progress in improving and extending the content of the portal as well as about the progress in planning its re-launch in a visible event.
Additional file 1 of Serum methylation of GALNT9, UPF3A, WARS, and LDB2 as noninvasive biomarkers for the early detection of colorectal cancer and advanced adenomas
Creators: name: Gallardo-Gómez, María
name: Rodríguez-Girondo, Mar
name: Planell, Núria
name: Moran, Sebastian
name: Bujanda, Luis
name: Etxart, Ane
name: Castells, Antoni
name: Balaguer, Francesc
name: Jover, Rodrigo
name: Esteller, Manel
name: Cubiella, Joaquín
name: Gómez-Cabrero, David
name: De Chiara, Loretta
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1. Details about the bioinformatics preprocessing of methylation microarray data for biomarker discovery. Details about biomarker discovery analysis and robust biomarker prioritization. PCR conditions and primers for biomarker evaluation and validation in individual serum samples. Decision rules derived from the final models for de detection of colorectal advanced neoplasia. Table S1. Epidemiological and clinical data of patients with other tumors (n = 16). Table S2. Description of cfDNA pooled samples. Table S3. Primers, PCR conditions, and amplicon details for biomarker evaluation by pyrosequencing. Table S4. Description of the CpG candidate biomarkers obtained after the epigenome-wide methylation analysis. Fig. S1. ROC curve analysis for the 26 candidate biomarkers and SEPT9 for NN versus AN classification in the biomarker evaluation cohort (n = 48). Fig. S2. ROC curve analysis for the 20 selected biomarkers and SEPT9 for NN versus AN classification in the model validation cohort (n = 105).
sj-pdf-1-esp-10.1177_09589287211040412 – Supplemental Material for Wealth of children from single-parent families: Low levels and high inequality in Germany
Creators: name: Marx, Ive
name: Nolan, Brian
name: Lersch, Philipp M
name: Grabka, Markus M
name: Rüß, Kilian
name: Schröder, Carsten
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 160512 Social Policy

description: Supplemental Material, sj-pdf-1-esp-10.1177_09589287211040412 for Wealth of children from single-parent families: Low levels and high inequality in Germany by Philipp M Lersch, Markus M Grabka, Kilian Rüß and Carsten Schröder in Journal of European Social Policy
title: Conformational heterogeneity of the Pfr chromophore in plant and cyanobacterial phytochromes
Creators: name: Velazquez Escobar, Francisco
name: Stetten, David Von
name: Günther-Lütkens, M.
name: Keidel, A.
name: Michael, N.
name: Lamparter, T.
name: Essen, Lars-Oliver
name: Hughes, J.
name: Gärtner, W.
name: Yang, Yang
name: Heyne, Karsten
name: Mroginski, M. A.
name: Hildebrandt, P.
Publisher: name: Freie Universität Berlin
Year: 2015
Subjects: subject: phytochrome
subject: tetrapyrrole
subject: isomerization
subject: structural heterogeneity
subject: hydrogen bonding
subject: resonance Raman spectroscopy
subject: time-resolved IR spectroscopy
subject: quantum chemical calculations
classificationCode: 570
subject: Biowissenschaften; Biologie

description: Phytochromes are biological photoreceptors that can be reversibly photoconverted between a dark and photoactivated state. The underlying reaction sequences are initiated by the photoisomerization of the tetrapyrrole cofactor, which in plant and cyanobacterial phytochromes are a phytochromobilin (PΦB) and a phycocyanobilin (PCB), respectively. The transition between the two states represents an on/off-switch of the output module activating or deactivating downstream physiological processes. In addition, the photoactivated state, i.e., Pfr in canonical phytochromes, can be thermally reverted to the dark state (Pr). The present study aimed to improve our understanding of the specific reactivity of various PΦB- and PCB- binding phytochromes in the Pfr state by analysing the cofactor structure by vibrational spectroscopic techniques. Resonance Raman (RR) spectroscopy revealed two Pfr conformers (Pfr-I and Pfr-II) forming a temperature-dependent conformational equilibrium. The two sub-states—found in all phytochromes studied, albeit with different relative contributions—differ in structural details of the C-D and A-B methine bridges. In the Pfr-I sub-state the torsion between the rings C and D is larger by ca. 10° compared to Pfr-II. This structural difference is presumably related to different hydrogen bonding interactions of ring D as revealed by time-resolved IR spectroscopic studies of the cyanobacterial phytochrome Cph1. The transitions between the two sub- states are evidently too fast (i.e., nanosecond time scale) to be resolved by NMR spectroscopy which could not detect a structural heterogeneity of the chromophore in Pfr. The implications of the present findings for the dark reversion of the Pfr state are discussed.
Beaconing D1.1 Project Handbook And Quality Plan
Creators: name: Cartwright, Sharon
name: Beaufoy, Jayne
name: Arnab, Sylvester
Publisher: name: Zenodo
Year: 2018

description: The purpose of this document is to provide an overview of the internal management, administrative and quality procedures of the BEACONING project in order to ensure efficient project execution as well as high quality project results. The document will provide partners with a concise reference to the project management structure, tasks, responsibilities, reporting requirements, finance information and quality processes.
Additional file 1 of Demographic and clinical characteristics associated with advanced stage colorectal cancer: a registry-based cohort study in Saudi Arabia
Creators: name: Alsadhan, Norah
name: Alhurishi, Sultana A
name: Pujades-Rodriguez, Mar
name: Shuweihdi, Farag
name: Brennan, Cathy
name: West, Robert M
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Supplementary Material 1: Supplemental Methods File
title: Building Hyper View web sites
Creators: name: Faulstich, Lukas C.
Publisher: name: Freie Universität Berlin
Year: 1999
Subjects: classificationCode: 004
subject: Datenverarbeitung; Informatik

description: In this report a framework for building “virtual” web sites using the HyperView system is presented. Virtual web sites are web sites that offer information extracted and integrated from other web sites on the fly. The HyperView system already supports the demand-driven integration of information from different semistructured information sources into a graph database. The problem we are dealing with here is to query the database and generate HTML pages from the results as a response to HTTP requests received from the user. The returned HTML pages should hide the aspects of data extraction and integration and should give the user the impression of a single, coherent web site. We show first how HyperViews comprised of graph-transformation rules can be defined that generate HTML pages from the database. This way web sites for individual application schemata can be designed. In the second part we present a generic rule set that defines a web interface for HyperView graph databases with arbitrary schemata. This generic web interface can be customized for the particular application by annotating the database schema and chosing appropriate styles. The work presented in this report completes the HyperView approach in the sense that it closes the circle of extracting and integrating information from the web by again publishing the integrated data on the web. Our approach applies as well to the integration and generation of XML documents on the web.
The Gamma-Ray Emitting Nls1 1H 0323+342 And The Disc-Jet Connection
Creators: name: Kynoch, Daniel
name: Landt, Hermine
name: Ward, Martin
name: Done, Chris
Publisher: name: Zenodo
Year: 2018
Subjects: NLS1

description: The Fermi Gamma-Ray Space Telescope has detected gamma-ray emission from a rare sub-set of radio-loud narrow-line Seyfert 1 (NLS1) galaxies, confirming the presence of blazar-like jets. This discovery has challenged the paradigm that powerful, relativistic jets are only associated with large, elliptical galaxies hosting the most massive central black holes. The small population of gamma-ray emitting NLS1s extends the blazar population down to low black hole masses and so allows us to investigate how jets scale with black hole mass.

We have performed a detailed analysis of the comprehensive multi-wavelength data set assembled for the lowest-redshift gamma-ray emitting NLS1, 1H 0323+342. This involves application of accretion flow and jet emission models to explore the disc-jet connection in greater depth than previously possible. We show that standard scaling relations vastly overpredict the jet power of this source. That gamma-ray emitting NLS1s appear to host such low-powered jets may go some way to explaining why so few have been detected to date.
sj-docx-1-psp-10.1177_01461672211065286 – Supplemental material for The Social Consequences of Frequent Versus Infrequent Apologizing
Creators: name: Schumann, Karina
name: Ritchie, Emily G.
name: Forest, Amanda
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-psp-10.1177_01461672211065286 for The Social Consequences of Frequent Versus Infrequent Apologizing by Karina Schumann, Emily G. Ritchie and Amanda Forest in Personality and Social Psychology Bulletin
title: Key management rules for agricultural alpine newt breeding ponds based on habitat suitability models
Creators: name: Troyer, Niels De
name: Forio, Marie Anne Eurie
name: Roels, Karen
name: Meester, Luc De
name: Lemmens, Pieter
name: Declerck, Steven A. J.
name: Martens, Koen
name: Goethals, Peter
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: Alpine newt
subject: Habitat suitability models
subject: Classification tree
subject: Machine learning
subject: Independent validation
subject: Pond management
classificationCode: 570
subject: Biowissenschaften; Biologie

description: The alpine newt, Ichthyosaura alpestris, is very sensitive to habitat destruction and alteration which has led to declining populations across Europe. As this species is protected through the Bern Convention, it is essential to have a comprehensive understanding of its habitat requirements to ensure proper conservation measures. We trained, validated and optimized classification tree models based on data on local aquatic habitat conditions from 125 farmland ponds scattered over Belgium and Luxembourg where the alpine newt commonly occurs. To obtain user-friendly and representative models, data was preprocessed and stratified after which different degrees of pruning were applied for model optimization. In order to check the model's applicability for management, we predicted alpine newt occurrence with an independent dataset. The most robust and reliable model revealed that fish absence was the major driving factor followed by the thickness of the sludge layer. We found that fish presence established alpine newt absence and that fishless ponds with a sludge layer of 15 cm or more were predicted to host no alpine newts. The latter provides quantitative information for decision makers. Moreover, our results indicated that the amount of sludge could be associated with eutrophication and erosion. Regarding management practices, it is advised to assure the absence of fish and reduce sludge accumulation in ponds designated for the conservation of alpine newts, for example by designing temporary ponds not fed through fish-containing surface waters. Furthermore, we recommend to install buffer strips around a pond to reduce nutrient and soil run-off from the terrestrial environment.
Additional file 1 of Radiation in an emergency situation: attempting to respect the patient’s beliefs as reported by a minor
Creators: name: Yumoto, Tetsuya
name: Hongo, Takashi
name: Koide, Yasuhiro
name: Obara, Takafumi
name: Tsukahara, Kohei
name: Naito, Hiromichi
name: Nakao, Atsunori
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1
Operatsioonijärgse valuravi juhendi mõju hindamine
Creators: name: Lass, Jana
name: Valk, Helen
name: Toome, Valdo
name: Baburin, Aleksei
name: Ringmets, Inge
name: Marandi, Toomas
Publisher: name: Eesti Arst
Year: 2011
Subjects: operatsioonijärgne valuravi, valuravijuhend, valuravi kvaliteet

description: Eesmärk. Hinnata operatsioonijärgse valuravi juhendi mõju valuravi kvaliteedile, mõõdetuna valu tugevuse vähenemisena arvuskaalal ja muutustega valuvaigistite kasutuses.
 Metoodika. Uuring tehti PERHi kolmes ortopeedia osakonnas ajavahemikul septembrist 2005 kuni aprillini 2006. Uuringu esimeses etapis hinnati küsimustiku abil põlve või puusa totaalse endoproteesimise (TEP) läbi teinud patsientide valu tugevust ja valuvaigistite kasutust. Uuringu teise etapi algul võeti III ortopeedia osakonnas (sekkumisrühm) kasutusele valuravijuhend ning I ja II ortopeedia osakonnas (kontrollrühm) jätkati valuravi varasemal viisil. Juhendi kasutuselevõtu järel hinnati patsientide valu tugevust ja valuvaigistite kasutust.
 Tulemused. Uuringus osales 206 patsienti (104 esimeses ja 102 teises etapis). Sekkumisrühmas vähenes valu tugevus pärast valuravijuhendi rakendamist, kuid muutus polnud statistiliselt oluline. Oluliselt muutus valuvaigistite manustamisviis: vähenes lihasesiseselt manustatud ja suurenes suu kaudu manustatud valuvaigistite osakaal.
 Järeldused. Uuring näitas, et valuravijuhendi positiivne mõju valuravi kvaliteedile avaldub peamiselt muutustena valuvaigistite kasutuses ja mõõdukamalt muutustena patsientide valutugevuse hinnangutes.


 Eesti Arst 2011; 90(6):263–269
description: Eesti Arst, Juuni 2011
sj-docx-1-psp-10.1177_01461672211062401 – Supplemental material for Turning Tables: Offenders Feel Like “Victims” When Victims Withhold Forgiveness
Creators: name: Thai, Michael
name: Wenzel, Michael
name: Okimoto, Tyler G.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-psp-10.1177_01461672211062401 for Turning Tables: Offenders Feel Like “Victims” When Victims Withhold Forgiveness by Michael Thai, Michael Wenzel and Tyler G. Okimoto in Personality and Social Psychology Bulletin
title: Stressors, coping and symptoms of adjustment disorder in the course of the COVID-19 pandemic - study protocol of the European Society for Traumatic Stress Studies (ESTSS) pan-European study
Creators: name: Lotzin, Annett
name: Acquarini, Elena
name: Ajdukovic, Dean
name: Ardino, Vittoria
name: Böttche, Maria
name: Bondjers, Kristina
name: Bragesjö, Maria
name: Dragan, Małgorzata
name: Grajewski, Piotr
name: Figueiredo-Braga, Margarida
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: COVID-19
subject: pandemic
subject: disaster
subject: coronavirus
subject: mental health
subject: stressors
subject: stress-related disorders
subject: coping style
classificationCode: 150
subject: Psychologie

description: Background: During the current COVID-19 pandemic, the people in Europe are exposed to self-isolation, quarantine, job loss, risk of contracting COVID-19, or grief of loved ones. Such a complex array of stressors may lead to symptoms of adjustment disorder or posttraumatic stress disorder. This research protocol describes a study launched by the European Society of Traumatic Stress Studies (ESTSS) to investigate the impact of the COVID-19 pandemic on symptoms of adjustment disorder across European countries. Objective: The longitudinal online cohort study aims (1) to explore psychosocial reactions to the COVID-19 pandemic across ten European countries; (2) to examine the relationships between risk and resilience factors, stressors and symptoms of adjustment disorder during the pandemic; and (3) to investigate whether these relationships are moderated by coping behaviours. Method: In ten countries (Austria, Croatia, Georgia, Germany, Italy, Lithuania, Netherlands, Poland, Portugal, and Sweden), between 1,000 and 2,000 participants will be recruited, depending on the size of the country. Participants will be assessed at two timepoints with a six-month interval. Following a conceptual framework based on the WHO's social framework of health, an assessment of risk and resilience factors, COVID-19 related stressors and pandemic-specific coping behaviours will be measured to estimate their contribution to symptoms of adjustment disorder. The Adjustment Disorder New Module 8 (ADNM-8) will be used to assess symptoms of adjustment disorder. As a secondary measure, symptoms of posttraumatic stress disorder will be measure using the Primary Care PTSD Screen for DSM-5 (PC-PTSD-5). Data analysis: The relative contribution of risk factors, resilience factors, and stressors on symptoms of adjustment disorder or symptoms of posttraumatic stress disorder will be estimated using multilevel analysis. To determine the moderating effects of different types of coping behaviours on these relationships, a multilevel mediation analysis will be carried out.
Perkutaanne koletsüstostoomia: ravivõimalus pikalt kestnud ägeda kalkuloosse koletsüstiidi korral
Creators: name: Treial, Alo
name: Ulst, Kai
name: Lepner, Urmas
Publisher: name: Eesti Arst
Year: 2011
Subjects: perkutaanne koletsüstektoomia, äge kalkuloosne koletsüstiit, laparoskoopiline koletsüstektoomia

description: Eesmärk. Ägeda kalkuloosse koletsüstiidi valikravi on laparoskoopiline koletsüstektoomia. Pikalt kestnud haiguse korral (sümptomite kestus üle 72 tunni) on kirurgiline ravi seotud suurema tüsistuste riskiga ning konversiooni sageduse kasvuga. Sellises olukorras võiks olla heaks valikuks perkutaanne koletsüstostoomia (PK) ning edasilükatud laparoskoopiline koletsüstektoomia.
 Uurimismaterjal ja -meetodid. Retrospektiivselt analüüsiti 77 haiget, kellel oli pikalt kestnud äge kalkuloosne koletsüstiit ja operatsioonirisk oli väike ning kellel oli kirurgilise ravi alternatiivina kasutatud sapipõie dreenimist ehk perkutaanset koletsüstostoomiat. Haigeid jälgiti keskmiselt 26 kuu vältel.
 Tulemused. PK oli edukas 100%-l juhtudest, olulisi tüsistusi ega letaalseid juhte ei esinenud. Kliiniliseks paranemiseks kulus keskmiselt 1,3 päeva (vahemik 1–5). Keskmiselt hoiti dreeni sapipõies 5,7 päeva (vahemik 2–12). 26% patsientidest haigestusid jälgimisperioodil korduvalt ägedasse koletsüstiiti. Jälgimisperioodi jooksul opereeriti plaaniliselt 42 haiget, sh laparoskoopiliselt 41, neist 1 (2,4%) patsiendil tuli üle minna lahtisele operatsioonile. Erakorraliselt opereeriti jälgimisperioodil 15 patsienti, neist 13 laparoskoopiliselt. Postoperatiivne kulg oli kõigil juhtudel probleemideta.
 Järeldused. PK on efektiivne ja ohutu protseduur pikalt kestnud ägeda kalkuloosse koletsüstiidi ravis, tagades kiire paranemise ja säilitades võimalused hilisemaks edukaks laparoskoopiliseks koletsüstektoomiaks.

Eesti Arst 2011; 90(6):270–273
description: Eesti Arst, Juuni 2011