cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Pipistrellus hesperidus
Creators: name: Monadjem, Ara
name: Schoeman, M. Corrie
name: Reside, April
name: P Io, Dorothea V.
name: Stoffberg, Samantha
name: Bayliss, Julian
name: (Woody) Cotterill, F. P. D.
name: Curran, Michael
name: Kopp, Mirjam
name: Taylor, Peter J.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Vespertilionidae
Pipistrellus
Pipistrellus hesperidus

description: Pipistrellus hesperidus (Temminck 1840)
Thirteen specimens were collected in the foothills and montane plateau of Mount Namuli, northern Mozambique and a further two individuals from southern Mozambique (Appendix I). Two prior specimens were recorded from central and southern Mozambique (Smithers and Lobão Tello, 1976). Hence, the species occurs throughout the country.
Field measurements: FA (adult male) 30.9 ± 1.03 (29.8–31.8, 3); Bm (adult male) 5.0 ± 0.50 (4.5–5.5, 3); FA (adult female) 31.5 (31.3–31.6, 2); Bm (adult female) 6.8 (6.5–7.0, 2).
description: Published as part of Monadjem, Ara, Schoeman, M. Corrie, Reside, April, P Io, Dorothea V., Stoffberg, Samantha, Bayliss, Julian, (Woody) Cotterill, F. P. D., Curran, Michael, Kopp, Mirjam & Taylor, Peter J., 2010, A recent inventory of the bats of Mozambique with documentation of seven new species for the country, pp. 371-391 in Acta Chiropterologica 12 (2) on pages 371-391, DOI: 10.3161/150811010X537963, http://zenodo.org/record/3944583
Neotanygastrella tricoloripes Duda 1925
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Neotanygastrella
Neotanygastrella tricoloripes

description: tricoloripes Duda, 1925: 224. Type locality: Costa Rica, Cartago, La Suiza de Turrialba. LT F (HNHM). Lectotype des. Wheeler 1963: 57. NT Distr.: Widespread in Neotropics. Ref.: Wheeler, 1957: 105, 1963: 57.
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 735, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
Hec1 Inhibitor Synergizes With Taxol in Breast Cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Increased cell proliferation is a hallmark of aggressive cancers, making inhibitors of cell proliferation logical anti-cancer agents. Our lab was the first to discover the cancer-associated mitosis-specific regulator, Hec1 (Highly Expressed in Cancer 1), which is essential for chromosome condensation, migration, and cell division. Importantly, overexpression of Hec1 is associated with poor prognosis of primary breast cancers in humans and is also found to initiate tumor formation in a mouse model, suggesting that Hec1 functions as an oncogene. We have developed a small molecule inhibitor of Hec1 function, called INH, which increases mitotic spindle abnormalities, chromosome segregation errors, and induces cell death. Despite the obvious benefit of INH treatment, drug delivery was an initial complication limiting future clinical use. We have successfully developed improved INH analogues with increased efficacy and “drug-likeness”. Because microtubules are critically important for the function of normal tissues, spindle poisoning drugs inevitably elicit a plethora of toxic side effects, indicating the need for new combinations of therapies that will shorten treatment times and reduce the negative side effects associated with treatment.

 The aims for this project are to:

 (1) Investigate the mechanisms involved in the response to INH; and

 (2) Perform in vitro (cell-based studies) and in vivo (animal studies) to determine if INH augments the effects of paclitaxel.

 The effect of INH and paclitaxel on cell growth and viability will be measured through standard growth assays. We will also explore the molecular mechanisms underlying the effects of these drugs (alone or in combination), including mitotic signaling pathways, spindle formation, cell cycle checkpoint activation, microtubule-kinetochore binding, mitotic inhibition, and cell death. Normal breast epithelial cells will be used in parallel with cancer cells to ensure breast cancer cell specificity. Additionally, animal (mouse) model-based assays will be used to evaluate the therapeutic efficacy of combination therapy on tumor formation.

 The results of this research could have significant clinical implications, as improvements in breast cancer therapy are essential to increasing therapeutic response and patient survival rates. Mitotic disruption through combined treatment with the Hec1 inhibitor, INH, and paclitaxel should inhibit the ability of cancer cells to maintain genomic stability, thereby increasing cell killing and enhancing the efficacy of existing therapeutic regimens.
Schlatter, Melchior
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Calcutta
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Palmomyia Grimaldi
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Palmomyia

description: Genus Palmomyia Grimaldi
Palmomyia Grimaldi in Grimaldi et al., 2003: 111. Type species, Palmomyia incerta Grimaldi, OD.
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 735, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
Schaezler, Joh. Lorenz
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Augsburg
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Therapeutic targeting to inhibit lung fibrosis progression
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease with a median survival time of only 3 to 5 years. Of great concern, there are no reliable biomarkers and specific therapies available to measure progression or treat the disease. Cigarette smoking is one of the most recognized factors associated with the development and progression of IPF. However, the mechanism by which smoking contributes to IPF pathogenesis is largely unknown. Through integration and analysis of detailed molecular data, we have identified the protein “myristoylated alanine-rich C kinase substrates” (MARCKS) as a putative smoke-responsive molecule involved in the abnormal activation of cells called fibroblasts in the lungs of IPF patients. Our preliminary data have shown that high production of a specific form of this protein, phospho-MARCKS, occurs in cells exposed to cigarette smoke and that another protein, AXL, is active in response to smoke. Given these and other observations, we hypothesize that smoke-triggered elevation of phospho-MARCKS cooperates with AXL to activate fibroblasts in response to smoke, contributing to lung fibrosis progression. To study this hypothesis, we will first confirm whether MARCKS and AXL are dysregulated in smoke-related IPF fibroblast cells and tissues. Next, we will characterize the role of AXL signaling in activating lung fibroblasts and conversion to a cell type that promotes fibrosis. Lastly, we will determine if blockade of AXL activity suppresses lung fibrosis and enhances drug efficacy. Achievement of these specific aims will characterize novel molecular mechanisms underlying smoke-mediated fibrosis progression, thereby providing novel therapeutic targets such as phospho-MARCKS and AXL for combating pulmonary fibrosis.
Σύνδρομο Επαγγελματικής Εξουθένωσης των Επαγγελματιών Ψυχικής Υγείας στην Μετά-Covid Εποχή
Creators: name: Ντάκουλας, Λεωνίδας Ξενοφώντα
Publisher: name: Aristotle University of Thessaloniki
Year: 2024
Subjects: Πανδημία Κορονοιού
Σύνδρομο Επαγγελματικής Εξουθένωσης
Επαγγελματίες Ψυχικής Υγείας
COVID-19
Burnout Syndrome
Μental Health Professionals

description: Σκοπός της παρούσας διπλωματικής εργασίας ήταν η διερεύνηση του συνδρόμου της επαγγελματικής εξουθένωσης των επαγγελματιών ψυχικής υγείας στην Ελλάδα, κατά την μετά - covid εποχή. Αρχικά, έγινε αναφορά της ιστορικής αναδρομής και των σημαντικότερων σημείων – σταθμών της Ψυχικής Υγείας. Στην συνέχεια, έγινε λόγος για τις προκλήσεις που αντιμετωπίζουν οι επαγγελματίες του χώρου, μεταξύ αυτών, το σύνδρομο επαγγελματική εξουθένωσης καθώς και για το πως το τελευταίο, φάνηκε να εντείνεται σημαντικά, μετά την έναρξη της πανδημίας του κορονοιού. Επεξηγήθηκε η μεθοδολογία που χρησιμοποιήθηκε, η ανάλυση των αποτελεσμάτων καθώς και η σύγκριση των τελευταίων με τα ευρήματα άλλων μελετών της διεθνούς βιβλιογραφίας. Έπειτα, πραγματοποιήθηκε η αναλυτική παρουσίαση των συμπερασμάτων, όπως η συσχέτιση του burnout με τους δημογραφικούς και τους ψυχοκοινωνικούς παράγοντες στην εργασία αλλά και η συσχέτιση των αντιλήψεων των επαγγελματιών για την πανδημία, αναφορικά με το άγχος και την γενική τους υγεία. Τέλος, επισημάνθηκαν στοχευμένες παρεμβάσεις με σκοπό την μείωση του φαινομένου της επαγγελματικής εξουθένωσης στον συγκεκριμένο εργασιακό χώρο στην Ελλάδα, όπως αυτές της δημιουργίας δικτύων υποστήριξης στην εργασία και των ψυχοεκπαιδευτικών προγραμμάτων διαχείρισης του στρες των εργαζομένων.
description: The aim of this thesis was to investigate the burnout syndrome of mental health professionals in Greece in the post-covid era. Initially, the historical background and the most important points - milestones of Mental Health were mentioned. Then, the challenges faced by professionals in the field, including burnout syndrome and how the latter seemed to intensify significantly after the onset of the covid pandemic, were discussed. The methodology used, the analysis of the results and the comparison of the latter with the findings of other studies in the international literature were explained. Then, a detailed presentation of the findings was made, such as the association of burnout with demographic and psychosocial factors at work and the correlation of the professionals' perceptions of the pandemic with respect to stress and their general health. Finally, targeted interventions aimed at reducing the phenomenon of burnout in the workplace in Greece, such as the creation of support networks in the workplace and psycho-educational programs for the management of employee stress, were highlighted.
Schmid, L. F
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Bern
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Scotoecus hindei Thomas 1901
Creators: name: Monadjem, Ara
name: Schoeman, M. Corrie
name: Reside, April
name: P Io, Dorothea V.
name: Stoffberg, Samantha
name: Bayliss, Julian
name: (Woody) Cotterill, F. P. D.
name: Curran, Michael
name: Kopp, Mirjam
name: Taylor, Peter J.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Vespertilionidae
Scotoecus
Scotoecus hindei

description: Scotoecus hindei / albigula Thomas 1901, 1909
Six individuals referable to either S. hindei or S. albigula were collected from four sites across the country. There is confusion regarding the specific status of hindei / albigula (Monadjem et al., 2010), and therefore we have chosen to lump these two species until the genus has been revised. This species was first reported from Zinave National Park, southern Mozambique by Cotterill (2001 a).
Field measurements: FA (adult male) 34.2 ± 1.08 (33.4–35.4, 3); Bm (adult male) 11.7 ± 0.76 (11.0– 12.5, 3); FA (adult female) 33.5 ± 0.71 (32.9–34.0, 3); Bm (adult female) 8.0 (1).
description: Published as part of Monadjem, Ara, Schoeman, M. Corrie, Reside, April, P Io, Dorothea V., Stoffberg, Samantha, Bayliss, Julian, (Woody) Cotterill, F. P. D., Curran, Michael, Kopp, Mirjam & Taylor, Peter J., 2010, A recent inventory of the bats of Mozambique with documentation of seven new species for the country, pp. 371-391 in Acta Chiropterologica 12 (2) on pages 371-391, DOI: 10.3161/150811010X537963, http://zenodo.org/record/3944583
Schaub, J. J
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Basel
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
VR-VIRTUAL VOQELIK TEXNALOGIYASI
Creators: name: Turdiyeva, Latofat
name: Nurullayeva, Malika
name: Yaxiyaxonova, Muxiba
Publisher: name: Zenodo
Year: 2025

description: Bugungi dunyoda taʻlimning tez suratda oʻzgarayotgan, rivojlanayotgan jarayonida, kreativ va zamonaviy metodlar samaradorligini oshirish, interaktiv oʻqitish vositalaridan foydalanish, texnologiyalarning integratsiyasi, virtual platformalarda oʻquvchilar ishtirokini taʻminlash, masofaviy taʻlimning rivojlanishi kabi jarayonlarda samaradorlikni oshirishda muhim rol oʻynaydi. Ushbu metodlar oʻquvchilarning mustaqil fikrlash va yaratuvchanlik qobiliyatini rivojlantirish, jamiyat rivojlanishi uchun foydasi tegadigan ish bilan shugʻullanishiga yordam beradi, oʻquvchilarning talablariga mos keluvchi shakllarda oʻrganishni taʻminlash orqali ularni oʻrganishni yaxshilaydi hamda oʻquvchilarni bilimni oʻzlashtirish jarayonlarida shaxsiy maslahatlar berish.
Palmomyia incerta Grimaldi in Grimaldi et al. 2003
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Palmomyia
Palmomyia incerta

description: incerta Grimaldi in Grimaldi et al., 2003: 111. Type locality: Colombia, Chocó, Sampichi. HT M (AMNH). NT Distr.: Colombia.
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 735, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
title: A Multi-disciplinary, Whole-of-Family Approach to Supporting Parents with Mental Illness
Creators: name: Nicholson, Joanne
Publisher: name: eScholarship@UMMS
Year: 2010

description: Summary: Family members are likely to have multiple and overlapping needs & roles – individuals with mental illness, carers & siblings. There are many opportunities & strategies for intervention. The best care requires the engagement of multiple stakeholders working in partnership.
DEVELOPMENT OF ANTIBIOTIC RESISTANCE IN POINT-OF-USE WATER FILTRATION SYSTEMS
Creators: name: Ken-Opurum, Ejike A
Publisher: name: Purdue University Graduate School
Year: 2024
Subjects: classificationCode: 410303
subject: Bioremediation
classificationCode: 410305
subject: Environmental marine biotechnology
classificationCode: 400513
subject: Water resources engineering
classificationCode: 310799
subject: Microbiology not elsewhere classified
classificationCode: 310704
subject: Microbial genetics
classificationCode: 401104
subject: Health and ecological risk assessment

description: Antibiotic resistance among bacteria is a growing public health concern and can result in treatment failure and economic loss. Point-of-use (POU) water filtration systems have been often used to remove contaminants from drinking water but the potential development of antibiotic resistance in POU systems has not been fully investigated. This study investigated the development of biofouling and the emergence of antibiotic resistance in activated carbon (AC) and reverse osmosis (RO) POU filters. Both filters experienced significant biofouling during short-term and long-term testing, characterized by microbial biomass and organic matter accumulation. Microbial growth and horizontal transfer of antibiotic resistance genes were observed in both systems, which were influenced by treatment capacity and nutrient availability. Phosphorus concentration was found to play a significant role in promoting microbial growth and horizontal gene transfer. Furthermore, the study examined the impact of biofouling on filter performance and removal of emerging contaminants, such as per- and polyfluoroalkyl substances (PFAS). While PFAS were effectively removed by both AC and RO filters, long-chain PFAS removal efficiencies were affected by biofouling development, especially in the AC system. The presence of emerging contaminants may contribute to the complexity of biofouling and affect antibiotic resistance dynamics in water treatment systems. Both short-term and long-term filtration experiments showed that fouling development and microbial growth may play an important role in the development of antibiotic resistance through horizontal gene transfer. Understanding the interplay between biofouling, antibiotic resistance, and emerging contaminants is crucial for optimizing water treatment processes and mitigating public health risks. Further research is needed to develop effective strategies for controlling biofouling and preventing the spread of antibiotic resistance in water treatment systems to safeguard human health.
in vivo monocyte depletion in acute SIV infection
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Human immunodeficiency virus (HIV) can enter and damage the brain of HIV-infected individuals, a disease called AIDS-associated dementia. White blood cells called monocytes represent major targets for HIV infection and are thought to transport HIV into the brain. HIV-infected monocytes in the brain can lead to inflammation and damage as they produce a variety of toxic products that kill brain cells. However many aspects regarding the migration of monocytes to the brain in HIV infection remain undefined. Here, we propose that peripheral blood monocyte depletion during the acute infection phase prevents monocyte brain entry and viral neuroinvasion. Our approach to deplete blood monocytes will utilize administration of toxin-containing lipid vesicles that will be taken up by monocytes in the blood and trigger their cell death. Significance Identifying the characteristics of circulating, activated monocytes during acute SIV infection and defining mechanism(s) of early brain entry could lead to novel drug targeting and treatment options that inhibit brain inflammation by targeting specific monocytes.Development of such treatment options is particularly critical in the era of highly active anti-retroviral therapy (HAART), which is associated with neurological disease in many HIV+ patients here in California and elsewhere, based on higher life expectancy and poor drug accessibility across the CNS barrier.
Scaptodrosophila latifasciaeformis Duda 1940
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Scaptodrosophila
Scaptodrosophila latifasciaeformis
Drosophila
Drosophila mirim

description: latifasciaeformis (Duda), 1940: 22 (Drosophila). Type locality: Uganda, Katona, Mujenje. LT M (ZMHU) Lectotype des. Vilela & Bächli 1990: 124. AF NE NT Distr.: Widespread tropical and subtropical areas, not Oriental. Colombia (Cundinamarca (Fusagasugá), Magdalena (Sierra Nevada de Santa Marta)). Refs.: Wheeler, 1957: 81; Hunter & Navarro, 1969: 1102; Hoenigsberg 1995a: 87, 1995b: 177.
mirim Dobzhansky & Pavan, 1943: 62. Type locality: Brazil, São Paulo, Bertioga. HT M (MZUSP). Syn. Pavan, 1952: 11.
baeomyia Wheeler, 1949b: 145. Type locality: Mexico, Jalisco, Michoacan, Nuevo Leon, USA. South Carolina: Georgetown, Santee River. HT M (AMNH)?. Syn. Wheeler in Burla, 1954a: 125.
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 736, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
Elucidating targets of costimulatory signals against AIDS
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: In the immune system, CD8+ killer T cells (CTLs) represent a uniquely powerful effector population, which is able to specifically clear or kill AIDS-related tumors. However in AIDS-related-tumor patients, many tumors evade immune responses, and specifically this is associated with a loss of CTLs or weak CTL activity, such as AIDS-related primary effusion lymphoma (PEL), is an HIV-associated malignancy characterized by the ability of the tumor cells to specifically home in the serous body cavities. Defining the nature of the molecules that regulate CTLs is therefore essential to understanding areas that might lead to therapeutical targeting of CTLs. Costimulatory signals from T cell expressed surface proteins are capable of promoting CTLs formation and high activity. We recently have identified several molecular targets of costimulatory signals (Akt, Bcl-xL/Bcl-2, Survivin, JNK, NF-kB) that might be critical to CTLs activity. Sustained and periodic Akt signaling from costimulation has an integral role in regulating T cell longevity. Costimulation drives expression of Bcl-xL and Bcl-2 is essential for T cell survival. Survivin, an inhibitor of apoptosis family member, represents a critical costimulation-regulated molecule that functions during T cell division, and in concert with anti-apoptotic Bcl-2 molecules, to control the extent of clonal expansion. In addition to the intracellular signals we have already defined, we will also investigate the role of JNK and NF-kB as potential targets for controlling tumor-specific T cell reactivity, based on our recent observations that have also shown these molecules are highly regulated by costimulatory signals to T cells. Our research seeks to understand the importance of these molecules to CTLs, and through adoptive immunotherapy approaches to the suppression of AIDS-related tumor growth. Defining the molecular targets that drive and sustain T cell responses is important to understanding how AIDS-related tumor-reactive T cells can be controlled and will lead to new insights into novel targets for immunotherapy of AIDS-related tumors.
Schlub, J. J
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Basel
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Schmid-Bloch, Rudolf, I.U.D., Notar
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Basel
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Scotophilus dinganii
Creators: name: Monadjem, Ara
name: Schoeman, M. Corrie
name: Reside, April
name: P Io, Dorothea V.
name: Stoffberg, Samantha
name: Bayliss, Julian
name: (Woody) Cotterill, F. P. D.
name: Curran, Michael
name: Kopp, Mirjam
name: Taylor, Peter J.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Vespertilionidae
Scotophilus
Scotophilus dinganii

description: Scotophilus dinganii (A. Smith 1833)
Twenty-five individuals were recorded from eight sites in southern and northern Mozambique. It is possible that the species has been overlooked in central Mozambique since it was recorded there in the past (Smithers and Lobão Tello, 1976).
Field measurements: FA (adult male) 52.7 ± 2.21 (50.2–56.6, 7); Bm (adult male) 23.9 ± 2.94 (21.5–29.5, 7); FA (adult female) 53.4 ± 1.99 (50.3– 57.2, 18); Bm (adult female) 26.4 ± 5.17 (18.0– 37.0, 18).
description: Published as part of Monadjem, Ara, Schoeman, M. Corrie, Reside, April, P Io, Dorothea V., Stoffberg, Samantha, Bayliss, Julian, (Woody) Cotterill, F. P. D., Curran, Michael, Kopp, Mirjam & Taylor, Peter J., 2010, A recent inventory of the bats of Mozambique with documentation of seven new species for the country, pp. 371-391 in Acta Chiropterologica 12 (2) on page 385, DOI: 10.3161/150811010X537963, http://zenodo.org/record/3944583
title: Advisor/Mentor Role in Guiding Future Primary Care Physicians
Creators: name: Kadish, Stacey J.
name: Gentile, Gina M.
name: Sefton, Laura A.
name: Zanetti, Mary L.
name: Pugnaire, Michele P.
Publisher: name: University of Massachusetts Medical School
Year: 2009

description: One component of UMMS’s mission is to provide affordable, high-quality medical education to state residents and to increase the number of PCPs practicing in underserved areas of the state.

This study responds to our growing need to recruit future PCPs by investigating differences in relationships with advisors/mentors between those students who pursue a primary care residency and those who do not.

Presented at the AAMC (Association of American Colleges) Annual Meeting, RIME (Research in Medical Education) Program, November 2009.
Mayer
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Hegenheim
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Scotophilus leucogaster
Creators: name: Monadjem, Ara
name: Schoeman, M. Corrie
name: Reside, April
name: P Io, Dorothea V.
name: Stoffberg, Samantha
name: Bayliss, Julian
name: (Woody) Cotterill, F. P. D.
name: Curran, Michael
name: Kopp, Mirjam
name: Taylor, Peter J.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Vespertilionidae
Scotophilus
Scotophilus leucogaster

description: Scotophilus leucogaster (Cretzschmar 1826)
A single individual was collected from mopane woodland near the Kruger National Park boundary in southern Mozambique. This constitutes the first recent record of this species for the country. Four specimens assigned to this species are mentioned in Van Cakenberghe and Seamark (2008), but these are based on old specimens that may refer to S. cf. viridis which is applied here as the available name for the smallest, yellow-bellied Scotophilus species in Southern Africa (see Scotophilus cf. viridis below). These four specimens require reexamination to establish exactly which species they refer to.
Field measurements: FA (adult male) 48.3 (1); Bm (adult male) 23.0 (1).
description: Published as part of Monadjem, Ara, Schoeman, M. Corrie, Reside, April, P Io, Dorothea V., Stoffberg, Samantha, Bayliss, Julian, (Woody) Cotterill, F. P. D., Curran, Michael, Kopp, Mirjam & Taylor, Peter J., 2010, A recent inventory of the bats of Mozambique with documentation of seven new species for the country, pp. 371-391 in Acta Chiropterologica 12 (2) on page 385, DOI: 10.3161/150811010X537963, http://zenodo.org/record/3944583
title: Weissdorn :
title: Richtlinien für die Durchführung der Prüfung auf Unterscheidbarkeit, Homogenität und Beständigkeit.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants,
Publisher: name: International Union for the Protection of New Varieties of Plants,
Year: 0
Subjects: Plants
Hawthorn
New Varieties of Plants

description: Zweck dieser Richtlinien („Prüfungsrichtlinien“) ist es, die in der Allgemeinen Einführung (Dokument TG/1/3) und deren verbundenen TGP-Dokumenten enthaltenen Grundsätze in detaillierte praktische Anleitung für die harmonisierte Prüfung der Unterscheidbarkeit, der Homogenität und der Beständigkeit (DUS) umzusetzen und insbesondere geeignete Merkmale für die DUS-Prüfung und die Erstellung harmonisierter Sortenbeschreibungen auszuweisen.
Scaptomyza Hardy
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Scaptomyza

description: Genus Scaptomyza Hardy
Scaptomyza Hardy, 1849: 361. Type species, S. graminum Fallen 1923: 8, OD?
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 736, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
Investigating the Interaction between Language and Theme in Literary Writing: A Multi-text Study
Creators: name: Zainab AK
name: Acheoah J. E.
Publisher: name: gjrpublication
Year: 2024

description: Given the fact that language use is an intentional act, several studies abound on the discrete functions of literary techniques in literary texts. In this study, we examine passages taken from different texts and genres to show that language takes certain dimensions to effectively convey themes. When writers use language skillfully to convey themes, it is not only of writer-reader importance, but also accentuates the goal-driven function of language use. The study hinges on the Text Analysis Theory. Within the framework of the theory, specific rule-governed linguistic structures and choice of words perform discrete communicative functions in written and spoken discourses. This study concludes that in literary writings, language interacts with themes as writers use theme-revealing expressions and message-laden word patterning to pungently convey themes.
On some nonlocal elliptic and parabolic equations
Creators: name: Jin, Tianling
Publisher: name: No Publisher Supplied
Year: 2012

description: We prove some results on the existence and compactness of solutions of a fractional Nirenberg problem  involving nonlocal conformally invariant operators. Regularity properties for solutions of some degenerate elliptic equations as well as a Liouville type theorem are established, and used in our blow up analysis. We also introduce a fractional Yamabe flow and show that on the conformal spheres it converges to the standard sphere up to a M"obius diffeomorphism. These arguments can be applied to obtain extinction profiles of solutions of some fractional porous medium equations, which are further used to improve a Sobolev inequality via a quantitative estimate of the remainder term.
Mangoaga & Co
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Havanna
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
A new marker for mammary epithelial stem cells?
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Mammary epithelial stem cells capable of reconstituting a fully functional gland exist and are thought to be responsible for the remarkable recycling capability of the gland through multiple pregnancies. We have discovered a new marker gene that is expressed in several other types of somatic stem cells and wish to determine if it is also preferentially expressed in mammary epithelial stem cells. If so, we will use its expression to enrich or purify the normal mammary epithelial stem cell and compare its differentiation capability in vivo and in cell culture.

 Our potential mammary stem cell marker gene is called maternal embryonic leucine-zipper kinase (MELK). MELK is preferentially expressed in several other stem cells (hematopoietic, neural, possibly in epidermal stem cells). These stem cells share a capability for self-renewal while retaining the potential for differentiating to different cell types. We will characterize expression of MELK during mammary gland development and test whether MELK expressing mammary cells have potential for reconstitution of a functional mammary gland. We will also compare mammary reconstitution capability in whole animals (mice) with mammary cell differentiation in three-dimensional cell culture. Our experiments will use excised mammary glands from the MELK-GFP transgenic mouse to examine the GFP and endogenous MELK RNA co-expression by histological methods. MELK-GFP epithelial cells will be isolated from virgin and pregnant animals using fluorescent activated cell sorting (FACS) and tested by transplantation into the cleared fat pads of 21-day old female mice of the same genetic background. We will also use cells in culture, grown in suspension to test the proliferative and differentiation potential of MELK-GFP cells.

 Understanding how mammary epithelial stem cells become quiescent, but retain the potential for proliferation and differentiation over many cellular generations, is likely to be a key to understanding events that lead to breast cancer and cancer cell dormancy. MELK has already been identified as a potential target for intervention in many types of cancer. Understanding its specific role in stem cell self-renewal or differentiation may lead to strategies of inducing “benign differentiation” as an alternative to the current use of chemotherapeutics and other drugs, often in a futile attempt to eradicate tumor cells.
Menschel, Nanette
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Frankfurt a. M.
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Scotophilus viridis
Creators: name: Monadjem, Ara
name: Schoeman, M. Corrie
name: Reside, April
name: P Io, Dorothea V.
name: Stoffberg, Samantha
name: Bayliss, Julian
name: (Woody) Cotterill, F. P. D.
name: Curran, Michael
name: Kopp, Mirjam
name: Taylor, Peter J.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Vespertilionidae
Scotophilus
Scotophilus viridis

description: Scotophilus cf. viridis (Peters 1852)
Twenty-five individuals were recorded from 10 sites in southern and northern Mozambique, making it the second most widespread species encountered during this study. The species has probably been overlooked in central Mozambique since it has been recorded there in the past (Smithers and Lobão Tello, 1976). Toward absolving the confusion associated with the status of this taxon, the smallest yellow-bellied species of Scotophilus in Southern Africa were assigned to S. viridis by Monadjem et al. (2010), distinct from the similar sized, but cream-bellied S. leucogaster. The recent paper by Jacobs and Barclay (2009), assigned the name S. ‘ mhlanganii ’ for their studied population of this small, yellow-bellied Scotophilus, but this most unfortunate introduction of a nomen nudum into an already confusing taxonomy has created more problems than it solves (Monadjem et al., 2010).
Field measurements: FA (adult male) 46.4 ± 1.22 (44.1–48.2, 17); Bm (adult male) 19.2 ± 2.90 (16.0– 24.5, 16); FA (adult female) 47.7 ± 2.06 (45.4–51.7, 8); Bm (adult female) 26.1 ± 7.06 (17.0–33.0, 6).
description: Published as part of Monadjem, Ara, Schoeman, M. Corrie, Reside, April, P Io, Dorothea V., Stoffberg, Samantha, Bayliss, Julian, (Woody) Cotterill, F. P. D., Curran, Michael, Kopp, Mirjam & Taylor, Peter J., 2010, A recent inventory of the bats of Mozambique with documentation of seven new species for the country, pp. 371-391 in Acta Chiropterologica 12 (2) on page 385, DOI: 10.3161/150811010X537963, http://zenodo.org/record/3944583
Scaptomyza bogotae Wheeler & Takada 1966
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Scaptomyza
Scaptomyza bogotae

description: bogotae Wheeler & Takada, 1966: 64. Type locality: Colombia, Bogotá area, 8700 ft. HT M (USNM). NT Distr.: Colombia.
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 736, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
Senn, Daniel
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Strassburg
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Schoppig, Salomon
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Ober-Hagenthal / Elsass
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Sommer, auf Hausmatt
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Olten
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
Menko, Eduard, & Co
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1833

description: Ort: Frankfurt a. M.
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
A Candidate Marker of Mammary Tumor Initiating Cells
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Breast tumors are heterogeneous and may include hyperplasia, invasive carcinoma, reactive stroma, supportive blood vessels, and inflammatory cells. One key objective in breast cancer research is to identify appropriate cells to target for therapeutic intervention. Recently, a small proportion of breast tumor mass has been found to be able to produce tumors upon transplantation in animal models. These tumor initiating cells, also termed cancer stem cells, are likely to be the appropriate target cells. However, little is known about the molecular markers and functional targets operating in such cells. On the other hand, several mouse models of mammary tumors have been established to investigate the molecular and cellular mechanisms of breast cancers in vivo. However, no functional markers of tumor initiating cells have been described yet. Identification of such markers will allow us to focus the efforts on the relevant population of tumor cells, both in a research and clinical setting.

 We propose that a new gene, called MELK (maternal embryonic leucine-zipper kinase) could be a functional marker for the tumor-initiating cells in breast cancer.

 MELK is expressed in a variety of tumor lines, including neuroblastomas, melanomas, hepatocellular and adenocarcinomas, papillomas, lymphoma, and germ cell tumors. The exact role of MELK in development and adults is uncertain, although similar kinases are associated with cell survival, cell cycle regulation, and RNA splicing functions. Our hypothesis is that MELK expression in mammary tumors labels the “cancer stem cells.”

 We will use a transgenic mouse model to identify tumor-initiating cells in mammary tumors. We have generated mice where the Green Fluorescent Protein (GFP) is expressed under the control of a MELK promoter (gene regulatory) element. These transgenic mice will allow us to visualize and study the cells that express MELK/GFP markers. We will cross these “reporter mice” with another transgenic strain overexpressing oncogenes (e.g., PyMT or Wnt1) specific to mammary tissue. These double-transgenic mice allow us to investigate the MELK expression in mammary tumors and stem cells.
Nanotherapy for Breast Cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Macrophages are versatile, plastic cells that are a key component of the body’s immune system. They have a variety of biological roles which include antigen “presentation”, a crucial role in initiating an immune response, scavenging debris, tissue remodeling and killing target cells such as bacteria etc. Macrophages are often prominent in tumor tissues, comprising up to 80% of the cell mass in breast carcinoma. Evidence currently available suggests that these tumor associated macrophages (TAMs) are reprogrammed by cancer cells and have little cytotoxicity for tumor cells. In fact, TAMs actually promote tumor cell proliferation and metastasis by secreting a wide range of chemicals. Due to their high concentration in breast tumor tissues, TAMs provide an ideal target for anti-breast cancer therapies, but selectively delivering drugs to kill TAMs with minimal side-effects is a major hurdle.

 The goal of this project is to work at the interface of nanotechnology and medicine to design “smart” nanoparticles that will selectively target and kill TAMs, thereby suppressing tumor progression and metastasis. Recent advances in nanoparticle design, when properly integrated with the evolving knowledge of tumor microenvironment biology, can provide an ideal platform to overcome the challenges associated with conventional breast cancer therapies. Recently it was shown for the first time that legumain, a member of the endopeptidase family is highly overexpressed by TAMs in murine and human breast tumor tissues and hence provides an ideal starting point for breast tumor targeting. First, we will use a novel strategy to change the shape of nanoparticles that will endow them with the “stealth” to remain in circulation for longer times by evading the body’s reticuloendothelial system. This approach should increase the ability of TAM-directed nanoparticle to “home” in on target tumor sites. Next, to validate TAM targeting, we will use well defined macrophage cell lines and TAMs isolated from mouse breast tumor tissues. The goal is to identify specific TAM molecular “biomarkers” that can be targeted. Finally, the “stealth” nanoparticles will be made functional with targeting moieties, such as antibodies to legumain or other biomarkers identified in the course of these studies.

 The proposed study has two innovative elements: (1) Instead of directly targeting and killing cancer cells, an approach that has met with limited success so far because of inefficient targeting and risk of side-effects due to high toxicity of anti-cancer drugs, we seek to alter the tumor microenvironment by targeting and killing TAMs that support

 angiogenesis and metastasis; and (2) to make the drug carrying nanoparticles more potent for anti-cancer therapy I propose to change their morphology to endow them with the “stealth” and give them an additional level of selectivity for tumor sites.
Miniopterus fraterculus Thomas and
Creators: name: Monadjem, Ara
name: Schoeman, M. Corrie
name: Reside, April
name: P Io, Dorothea V.
name: Stoffberg, Samantha
name: Bayliss, Julian
name: (Woody) Cotterill, F. P. D.
name: Curran, Michael
name: Kopp, Mirjam
name: Taylor, Peter J.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Miniopteridae
Miniopterus
Miniopterus fraterculus

description: Miniopterus cf. fraterculus Thomas and
Schwann 1906
Five adult male bats referable to this species were captured on the lower slopes of Mount Namuli, with further specimens from Mount Mabu in northern Mozambique. The two specimens that were collected had greatest skull lengths of 14.3 and 14.8 mm, with head lengths of 16.0 and 16.2 mm, respectively. The three released individuals had head lengths of 15.8, 16.1 and 16.8 mm. These head and skull measurements are significantly shorter than Miniopterus natalensis but within the range of M. fraterculus. The closest population of M. fraterculus to that on Mount Namuli (and the nearby Mount Zomba in neighbouring Malawi) is> 1000 km away in South Africa (Monadjem et al., 2010) suggesting that this isolated population may be specifically distinct.
Field measurements: FA (adult male) 43.7 ± 0.95 (42.1–44.5, 5); Bm (adult male) 8.0 ± 0.35 (7.5– 8.5, 5).
description: Published as part of Monadjem, Ara, Schoeman, M. Corrie, Reside, April, P Io, Dorothea V., Stoffberg, Samantha, Bayliss, Julian, (Woody) Cotterill, F. P. D., Curran, Michael, Kopp, Mirjam & Taylor, Peter J., 2010, A recent inventory of the bats of Mozambique with documentation of seven new species for the country, pp. 371-391 in Acta Chiropterologica 12 (2) on page 385, DOI: 10.3161/150811010X537963, http://zenodo.org/record/3944583
Morgantina, Sicily
Creators: name: Jacob, Cynthia M.
Publisher: name: No Publisher Supplied
Year: 2012

description: The purpose of this dissertation is to prepare a publishable catalog of more than six hundred unpublished worked bone and ivory artifacts unearthed in successive archeological excavations of the second city of Morgantina, Sicily, beginning in 1955 and continuing until the present time.  To accomplish this, it was necessary to examine all these bone and ivory objects, to assess them in terms of relationship to the larger Greek koine of the Mediterranean basin, to categorize and describe them in detail, and to photograph them.      Morgantina, an inland Greek colony dating from the second quarter of the sixth century B.C., flowered after destruction by fire in 459 B.C. at the hands of an indigenous leader, Ducetius, and continued to flourish during the Hellenistic era.  The city was captured in 211 B.C., during the Roman invasion and conquest of Syracuse.  The city survived in diminished form from 211 B.C. to the mid-first century A.D.  Most of the bone and ivory objects cannot be dated more closely than the period 459 B.C., the date of the destruction by fire, to the first century A.D., when the city disappeared.    The Morgantina artifacts which are the subject to of this dissertation consist largely of items for daily use, such as utensils for personal grooming and jewelry for personal adornment, implements for writing, tools for a variety of purposes, handles, hinges and other structural and decorative components for furniture, game pieces, and miscellaneous pieces of uncertain application.  From study of these objects, one can conclude that all conform substantially to similar worked bone and ivory objects found throughout the wide geographical area constituting the Greek world prior to the first century A.D.  The Morgantina objects evidence strong connections to that Greek world, even with locales which could be considered far-flung geographically and temporally.  They do not, however, demonstrate the cultural flowering which other categories of artifacts from the city reflect.