cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Mode identification of MHD waves in an active region observed with Hinode/EIS
Creators: name: Kitagawa, Naomasa
name: Yokoyama, Takaaki
name: Imada, Shinsuke
name: Hara, Hirohisa
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: In order to better understand the possibility of coronal heating by MHD waves, we analyze Fe xii 195.12Å data observed with EUV Imaging Spectrometer (EIS) onboard Hinode. We performed a Fourier analysis of EUV intensity and Doppler velocity time series data in the active region corona. Notable intensity and Doppler velocity oscillations were found for two moss regions out of the five studied, while only small oscillations were found for five apexes of loops. The amplitudes of the oscillations were 0.4 - 5.7% for intensity and 0.2 - 1.2 kms-1 for Doppler velocity. In addition, oscillations of only Doppler velocity were seen relatively less often in the data. We compared the amplitudes of intensity and those of Doppler velocity in order to identify MHD wave modes, and calculated the phase delays between Fourier components of intensity and those of Doppler velocity. The results are interpreted in terms of MHD waves as follows: (1) few kink modes or torsional Alfv'en mode waves were seen in both moss regions and the apexes of loops; (2) upwardly propagating and standing slowmode waves were found inmoss regions; and (3) consistent with previous studies, estimated values of energy flux of the waves were several orders of magnitude lower than that required for heating active regions.
description: 22 pages, 1 table, 5 figures
Density functional theory, molecular docking and in vivo muscle relaxant, sedative, and analgesic studies of indanone derivatives isolated from Heterophragma adenophyllum
Creators: name: Aljohani, Abdullah S. M.
name: Abu-Izneid, Tareq
name: Shah, Zafar Ali
name: Rashid, Umer
name: Ayub, Khurshid
name: Rauf, Abdur
name: Muhammad, Naveed
name: Alhumaydhi, Fahad A.
name: Asghar, Maria
name: Mubarak, Mohammad S.
name: Shariati, Mohammad Ali
name: Zhang, Haiyuan
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Heterophragma adenophyllum (HA) is an important medicinal plant which is used in traditional medicine for the treatment of muscular tension and pain. Herein, we report the isolation of methyl,1,2-dihydroxy-2-(3-methylbut-2-en-1-yl)-3-oxo-2,3-dihydro-1H-indene-1-carboxylate (1), from the roots of H. adenophyllum. The isolated compound 1 was evaluated for in vivo muscle relaxant, sedative, and analgesic potential in Swiss albino mice. Results revealed that the isolated compound 1 exhibited a dose- and time-dependent muscle coordination (51%) and a significant (p p 1. Furthermore, the experimental results were compared with the theoretical studies by using density functional theory (DFT). The stability of the compound as well as the flow of electrons was determined by the calculated Frontier orbital analysis. The calculated stretching frequencies, 1H-NMR/13C-NMR chemical shift values and UV-visible spectra were found to be in agreement with experimental values. The results obtained from molecular docking studies were used to explore the mechanism of analgesic and muscle relaxant activity. Communicated by Ramaswamy H. Sarma
Tourism diversification paths in ski mid-mountain territories: any transformations?
Creators: name: Rouch, Laura
name: George, Emmanuelle
Publisher: name: arXiv
Year: 2025
Subjects: subject: Risk Management (q-fin.RM)
subject: FOS: Economics and business

description: In the context of adapting to global changes, the diversification of the tourist offer seems to be a solution for the mid-mountain areas, which are structured around and dependent on ski tourism. However, it remains unclear how tourism diversification occurs, what forms it can take and what it produces at a territorial scale. In this study, we apply a theory of regional diversification to the case of tourism in order to examine tourism diversification paths. We base our analysis on qualitative data collected on two French study areas: the intercommunities of the massif du Sancy and of the Haut-Chablais. Our results show a pattern in tourism diversification paths, following three steps that can lead to the abandonment of the perimeter of the ski resort. However, among the different types of tourism diversification trajectories, only a saltation form of tourism diversification can lead to the establishment of a larger and more diversified tourism system. Our findings also show that several types of tourism diversification paths can coexist at a territorial scale.
Characteristics of solar-like oscillations of clusters simulated by stellar population synthesis
Creators: name: Yang, Wuming
name: Li, Zhongmu
name: Meng, Xiangcun
name: Bi, Shaolan
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Using a stellar population-synthesis method, we studied the distributions of ν_max and Δν of simulated clusters with various ages and metallicities. Except for the confirmed peak (RC peak) of Δν of red-clump (RC) stars, i.e. core-helium burning stars, there are a gap and a main sequence (MS) peak in the distributions of ν_max and Δν of young clusters. The gap corresponds mainly to the Hertzsprung gap phase of evolution. The RC peak is caused by the fact that the radius of many RC stars near the zero-age horizontal branch concentrates in a certain range. The MS peak also results from the fact that many MS stars which are located in a certain mass range have an approximate radius in the early phase of MS. The MS peak barely exists in the simulated clusters with age < 1.0 Gyr. The location of the MS peak moves to a lower frequency with increasing age or metallicity, which may be applied to constrain the age and metallicity of young clusters. For the simulated clusters with Z = 0.02, the frequency of the location of the dominant RC peak increases with age when age < 1.2 Gyr, and then decreases with age when age > 1.2 Gyr; but it scarcely varies when age > 2.4 Gyr. This is relative to the degeneracy of the hydrogen-exhausted core at the time of helium ignition. In addition, the RC peak is not sensitive to the metallicity, especially for the clusters with age > 2.4 Gyr. Asteroseismical observation for clusters with age < 2.4 Gyr may aid in testing the theory of the degeneracy of the hydrogen-exhausted core. Moreover, for the clusters with 1.1 M{\odot} < M_hook < 1.3 M{\odot}, there are a MS gap and a peak on the left of the MS gap in the distributions ofν_max and Δν, which may be applied to constrain the central hydrogen abundance of stars in the MS gap and the peak.
description: Accepted for publication in MNRAS. 8 pages, 8 figures
Hardy's Non-locality Paradox and Possibilistic Conditions for Non-locality
Creators: name: Mansfield, Shane
name: Fritz, Tobias
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Hardy's non-locality paradox is a proof without inequalities showing that certain non-local correlations violate local realism. It is `possibilistic' in the sense that one only distinguishes between possible outcomes (positive probability) and impossible outcomes (zero probability). Here we show that Hardy's paradox is quite universal: in any (2,2,l) or (2,k,2) Bell scenario, the occurence of Hardy's paradox is a necessary and sufficient condition for possibilistic non-locality. In particular, it subsumes all ladder paradoxes. This universality of Hardy's paradox is not true more generally: we find a new `proof without inequalities' in the (2,3,3) scenario that can witness non-locality even for correlations that do not display the Hardy paradox. We discuss the ramifications of our results for the computational complexity of recognising possibilistic non-locality.
Short-Range B-site Ordering in Inverse Spinel Ferrite NiFe2O4
Creators: name: Ivanov, V. G.
name: Abrashev, M. V.
name: Iliev, M. N.
name: Gospodinov, M. M.
name: Meen, J.
name: Aroyo, M. I.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The Raman spectra of single crystals of NiFe2O4 were studied in various scattering configurations in close comparison with the corresponding spectra of Ni0.7Zn0.3Fe2O4 and Fe3O4. The number of experimentally observed Raman modes exceeds significantly that expected for a normal spinel structure and the polarization properties of most of the Raman lines provide evidence for a microscopic symmetry lower than that given by the Fd-3m space group. We argue that the experimental results can be explained by considering the short range 1:1 ordering of Ni2+ and Fe3+ at the B-sites of inverse spinel structure, most probably of tetragonal P4_122/P4_322 symmetry.
description: 10 pages, 5 figures, 6 tables
Universal Gravitational Informational Theory (TGIU) Framework
Creators: name: Virtosu, Sebastian
Publisher: name: Zenodo
Year: 2024

description: The Universal Gravitational-Informational Theory (TGIU) proposes a model where the observable universe arises from a 2D informational plane, comprising infinite information and potential energy, and a 1D potential gravity collapse direction. These planes interact at 90 degrees, generating motion, time, 3D space dimensions, matter, energy, and mass through a process of informational gradient collapse. This interaction underpins gravitational and informational dynamics, offering explanations for dark matter, dark energy, and cosmic expansion. Key predictions include gravitational-informational waves, continuous space-time creation, and applications for gravito-informatic devices, with potential for experimental validation. TGIU bridges classical and quantum theories, suggesting a fractal-holographic nature of reality.
Identification of potential anti-TMPRSS2 natural products through homology modelling, virtual screening and molecular dynamics simulation studies
Creators: name: Chikhale, Rupesh V.
name: Gupta, Vivek K.
name: Eldesoky, Gaber E.
name: Wabaidur, Saikh M.
name: Patil, Shripad A.
name: Islam, Md Ataul
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Recent outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a pandemic of COVID-19. The absence of a therapeutic drug and vaccine is causing severe loss of life and economy worldwide. SARS-CoV and SARS-CoV-2 employ the host cellular serine protease TMPRSS2 for spike (S) protein priming for viral entry into host cells. A potential way to reduce the initial site of SARS-CoV-2 infection may be to inhibit the activity of TMPRSS2. In the current study, the three-dimensional structure of TMPRSS2 was generated by homology modelling and subsequently validated with a number of parameters. The structure-based virtual screening of Selleckchem database was performed through ‘Virtual Work Flow’ (VSW) to find out potential lead-like TMPRSS2 inhibitors. Camostat and bromhexine are known TMPRSS2 inhibitor drugs, hence these were used as control molecules throughout the study. Based on better dock score, binding-free energy and binding interactions compared to the control molecules, six molecules (Neohesperidin, Myricitrin, Quercitrin, Naringin, Icariin, and Ambroxol) were found to be promising against the TMPRSS2. Binding interactions analysis revealed a number of significant binding interactions with binding site amino residues of TMPRSS2. The all-atoms molecular dynamics (MD) simulation study indicated that all proposed molecules retain inside the receptor in dynamic states. The binding energy calculated from the MD simulation trajectories also favour the strong affinity of the molecules towards the TMPRSS2. Proposed molecules belong to the bioflavonoid class of phytochemicals and are reported to possess antiviral activity, our study indicates their possible potential for application in COVID-19. Communicated by Ramaswamy H. Sarma
The growth of Turkeys 1. Growth of the body and feathers and the chemical composition of growth
Creators: name: R. M. Gous
name: C. Fisher
name: E. Tůmová
name: V. Machander
name: D. Chodová
name: J. Vlčková
name: L. Uhlířová
name: M. Ketta
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology

description: 1. The potential growth of modern turkey genotypes was measured using male and female BUT 6 (BUT) and Hybrid Converter (HYB) strains. At one-day-old, 720 male and 960 female poults were randomly allocated to 48 littered pens in two houses with 30 males or 40 females of each strain per pen. Five feeds of decreasing protein content were fed to both sexes during the growing period. 2. Birds were weighed at 1, 7, 14, 21, 35, 56, 77, 119 d (males only), 126 d (females only) and 140 d (males only) and, on each occasion, six birds were selected and removed for carcass analysis. 3. Growth was similar in both strains, but the growth rate of females appeared to decline relative to the earlier trajectory after 70 d, and this tendency being greater in HYB females. 4. HYB birds of both sexes had more feathers than BUT to 77 d, but thereafter these differences were non-significant. A single allometry between feather and body protein weight was observed over all genotypes with no differences apparent between sexes within strains. The Gompertz curve adequately described the growth of body protein, water and ash. 5. Body lipid (g/100g bodyweight) declined in the early stages of growth. This might reflect an energy deficiency in the diet or might indicate that the present description of lipid growth does not apply in turkeys as it does in other species. 6. Whereas the description of body growth, feather growth and the chemical components of growth given in this paper may not fully reflect the true potential of the genotypes used, nevertheless they provide useful information regarding the latest genotypes available in the turkey industry. Some of the observations suggested that current performance might be improved if further research is conducted regarding dietary energy transactions.
Higher charges and regularized quantum trace identities in su(1,1) Landau-Lifshitz model
Creators: name: Melikyan, A.
name: Pinzul, A.
name: Weber, G.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We solve the operator ordering problem for the quantum continuous integrable su(1,1) Landau-Lifshitz model, and give a prescription to obtain the quantum trace identities, and the spectrum for the higher-order local charges. We also show that this method, based on operator regularization and renormalization, which guarantees quantum integrability, as well as the construction of self-adjoint extensions, can be used as an alternative to the discretization procedure, and unlike the latter, is based only on integrable representations.
description: 27 pages; misprints corrected, references added
Genetic parameters of the thick-to-thin albumen ratio and egg compositional traits in layer-type chickens
Creators: name: Wan, Yi
name: Zhicheng Wang
name: Jiangxian Wang
name: Su, Hu
name: Guo, Xing
name: Jijun Wu
name: Qingxia Li
name: Ni,
name: Runshen Jiang
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: Science Policy
subject: Plant Biology

description: 1. Generating a robust egg albumen is one of the major factors contributing to interior egg quality owing to its nutritive value and superior appearance. However, the genetic factors regulating the proportion of thick albumen are poorly understood. 2. In this study, 1330 eggs were collected from 450 Rhode Island White layers, aged 40 weeks, to measure egg compositional traits for three successive days. The restricted maximum likelihood method was applied to estimate genetic parameters for the thick-to-thin albumen ratio and other egg compositional traits. A univariate animal model was fitted to calculate heritability for each trait. 3. The heritabilities of egg weight, yolk weight, albumen height, Haugh units, percentages of yolk, thick albumen, thin albumen and the thick-to-thin albumen ratio were 0.32, 0.34, 0.28, 0.47, 0.61, 0.39, 0.31, and 0.45, respectively. The percentage of thick albumen was negatively correlated genetically with all traits, and percentage of thin albumen was negatively correlated genetically with all traits except for Haugh units. The thick-to-thin albumen ratio was positively correlated genetically with egg weight, albumen height and Haugh units, with correlations ranging from 0.21 to 0.54. 4. The results indicated that the percentage of thick albumen and the thick-to-thin albumen ratio were found to be moderately to highly heritable, and selection for the thick-to-thin albumen ratio could be conducive to the improvement of egg albumen quality.
The effects of diesel exhaust on neutrophil functions in never-smokers, ex-smokers, and COPD patients
Creators: name: Wooding, Denise
Publisher: name: University of British Columbia
Year: 2020

description: Introduction: Traffic-related air pollution (TRAP) is associated with COPD epidemiologically, however the mechanism of this interaction remains unclear. Neutrophils, a key inflammatory cell in COPD, migrate to the lungs following TRAP exposure, but their functional role in this response is poorly understood. The aim of this study is to elucidate the effects of TRAP exposure on neutrophil function, using the model of diesel exhaust (DE). Methods: In vitro: Isolated peripheral blood neutrophils were incubated with diesel exhaust particles (DEPs) before quantifying activation marker expression, oxidative burst, and neutrophil extracellular traps (NETs). In vivo: Subjects from three groups (never-smokers, ex-smokers, and mild-moderate COPD) participated in a randomized double-blind controlled human exposure crossover study. Subjects were exposed on one occasion to filtered air and on another occasion to diluted DE. Blood and bronchoalveolar lavage (BAL) samples were used to assess the effect of DE on the number and function of pulmonary and systemic neutrophils. Results: DEPs increased CD66b, oxidative burst, and NET formation in vitro. Controlled human exposure to DE reduced the proportion of circulating band cells, increased NET formation in BAL, and resulted in lymphocytic but not neutrophilic inflammation. The effect of DE on band cells and peripheral CD182 expression was distinct in the COPD group. There was no effect on oxidative burst or activation marker expression in pulmonary neutrophils. Conclusion: Diesel exhaust increases some, but not all, neutrophil effector activities in vitro and in vivo. Two potential mechanisms for susceptibility in COPD patients were identified. These results demonstrate a functional role for neutrophils in the inflammatory response to diesel exhaust. The potential for DE-induced neutrophil activity to promote lung tissue damage and clinical features of COPD may be an area of future investigation.
Ferromagnetic spinel CuCr2Se4 studied by Raman spectroscopy and lattice dynamics calculations
Creators: name: Ivanov, V. G.
name: Iliev, M. N.
name: Wang, Y. -H. A.
name: Gupta, A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The lattice dynamics of the ferromagnetic spinel CuCr2Se4 (Tc = 430K) was studied experimentally by measuring the Raman spectra and theoretically by calculation of zone center phonon frequencies within a shell model. All Raman allowed modes (A1g + E_g + 3F2g) were identified and assigned to specific atomic motions. The relative intensity of the Raman lines varies strongly with excitation photon energy between 1.58 and 2.71 eV, but no significant phonon anomalies are observed near Tc.
description: 6 pages, 7 figures, 5 tables
Tackling COVID-19: identification of potential main protease inhibitors via structural analysis, virtual screening, molecular docking and MM-PBSA calculations
Creators: name: Al-Shar’i, Nizar A.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The widespread of the COVID-19 disease, caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), had severely affected the entire world. Unfortunately, no successful vaccines or antiviral drugs are currently available which leaves the scientific community under huge pressure to tackle this pandemic. Among the identified promising druggable targets, specific to this virus, is the main protease (Mpro) enzyme, which is vital for viral replication, transcription and packaging within the host cells. In this study, selective inhibition of the Mpro was sought via thorough analysis of its available structural data in the Protein Data Bank. To this end, COVID-19 Mpro crystal complexes were explored and the key interacting residues (KIRs) within its active site, that are expected to be vital for effective ligand binding, were identified. Based on these KIRs, 3D pharmacophore models were generated and used in virtual screening of different databases. Retrieved hits were docked into the active site of the enzyme and their MM-PBSA based free binding energies were calculated. Finally, ADMET descriptors were calculated to aid the selection of top scoring hits with best ADMET properties. Nine compounds with different chemotypes were identified as potential Mpro inhibitors. Further, MD simulations of a virtual complex of Mpro with one of the promising hits revealed stable binding which is indicative of good inhibitory potential. The identified compounds in this study are expected to support the global drug discovery efforts in fighting against this highly contagious virus by narrowing the searchable chemical space for potential effective therapeutics. Communicated by Ramaswamy H. Sarma
Question Isotropy
Creators: name: Ralston, John P.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The "cosmological principle" was set up early without realizing its implications for the horizon problem, and almost entirely without support from observational data. Consistent signals of anisotropy have been found in data on electromagnetic propagation, polarizations of QSOs and $CMB$ temperature maps. The axis of Virgo is found again and again in signals breaking isotropy, from independent observables in independent energy regimes. There are no satisfactory explanations of these effects in conventional astrophysics. Axion-photon mixing and propagation in axion condensates are capable of encompassing the data.
description: Published in Axions 2010: AIP Conf.Proc.1274:72-77,2010, edited by David Tanner
Examining personality for the selection and classification of soldiers: Validity and differential validity across jobs
Creators: name: Nye, Christopher D.
name: White, Leonard A.
name: Drasgow, Fritz
name: Prasad, Joshua
name: Chernyshenko, Oleksandr S.
name: Stark, Stephen
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology

description: A number of past studies have demonstrated that personality traits are modest predictors of workplace attitudes and behaviors and can provide incremental validity over cognitive ability. However, less is known about the utility of personality for job classification. In addition, concerns about the effects of faking on personality measures still remain. In this study, we examined the validity of a forced choice personality measure administered under operational conditions to explore the use of personality traits in high-stakes settings. In addition, we also examined the potential use of personality for classification into military occupational specialties (MOS). We explored these issues in a large sample of Soldiers from five different MOS to examine the prediction of performance during initial military training (IMT). Results indicated that composites of personality traits were valid predictors of performance and attrition and that these composites may be useful for classifying individuals into different military occupations. The implications of these results for Soldier selection and classification are discussed.
PromptForge :  Forge Your Perfect Prompts for AI
Creators: name: Pathak, Vinayak
Publisher: name: Zenodo
Year: 2025

description: PromptForge introduces a fresh take on how we interact with AI by building a dedicated marketplace for prompts—those small but mighty pieces of text that steer AI models. This platform creates a unified space where creators can sell custom-crafted prompts, and users can easily discover and purchase high-quality, well-structured inputs for a variety of use cases—ranging from creative storytelling to technical workflows. While most existing solutions are scattered, lack moderation, and don’t offer secure payments, PromptForge solves these issues with a seamless system powered by Stripe, intuitive shop management, and community feedback loops. Built on a modern stack including Next.js, MongoDB, and Prisma, PromptForge delivers both performance and scalability. The paper unpacks its architecture, development cycle, and impact, while also outlining future plans like AI-based suggestions, blockchain-backed ownership, and language localization.
Inhibitory effects of curcumin on aldose reductase and cyclooxygenase-2 enzymes
Creators: name: Mirzaei, Mahmoud
name: Harismah, Kun
name: Soleimani, Mehdi
name: Mousavi, Sarah
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Diabetes is very much known as a wide-spread disorder all around the world with serious complications for the diabetic patient. In order to reduce these complications, inhibition the activity of aldose reductase (AR) and cyclooxygenase-2 (COX-2) enzymes is a proposed pathway. Within this work potency of curcumin (CUR) for the proposed enzymatic inhibition has been performed by the in silico methodologies. The main purposes of this work; evaluating first, the effect of original CUR on each of AR and COX-2 enzymes; second, the best CUR derivative for the individual action; third, the best CUR derivative with common effect on both enzymes, the results have been analyzed. The results based on the scoring factors of 66 derivatives indicated that C60 could be seen specific for AR and C62 could be seen specific for COX-2 enzyme. Further analysis indicated that C19 could be considered as a ligand with common Rank for interactions with both enzymes. The quantitative EB results indicated that the strength of interacting ligand…target complexes of C19, C60 and C62 are stronger than original inhibitors of AR and COX-2 whereas this trend has not been seen for the complexes of original CUR. The qualitative representations of interacting counterparts revealed that he proposed ligands could interact with those important parts of enzymes, especially NADPH of AR besides proper amino acids of active site for both of AR and COX-2 enzymes. The in silico methodologies have been performed based on Density Functional Theory calculations and Molecular Docking simulations. Communicated by Ramaswamy H. Sarma
Adiabatic times for Markov chains and applications
Creators: name: Bradford, Kyle
name: Kovchegov, Yevgeniy
Publisher: name: arXiv
Year: 2010
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60J10, 60J27, 60J28

description: We state and prove a generalized adiabatic theorem for Markov chains and provide examples and applications related to Glauber dynamics of Ising model over Z^d/nZ^d. The theorems derived in this paper describe a type of adiabatic dynamics for l^1(R_+^n) norm preserving, time inhomogeneous Markov transformations, while quantum adiabatic theorems deal with l^2(C^n) norm preserving ones, i.e. gradually changing unitary dynamics in C^n.
On the Preliminary Design of Multiple Gravity-Assist Trajectories
Creators: name: Vasile, Massimiliano
name: DePascale, Paolo
Publisher: name: arXiv
Year: 2011
Subjects: subject: Optimization and Control (math.OC)
subject: Neural and Evolutionary Computing (cs.NE)
subject: Systems and Control (eess.SY)
subject: Space Physics (physics.space-ph)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Physical sciences

description: In this paper the preliminary design of multiple gravity-assist trajectories is formulated as a global optimization problem. An analysis of the structure of the solution space reveals a strong multimodality, which is strictly dependent on the complexity of the model. On the other hand it is shown how an oversimplification could prevent finding potentially interesting solutions. A trajectory model, which represents a compromise between model completeness and optimization problem complexity is then presented. The exploration of the resulting solution space is performed through a novel global search approach, which hybridizes an evolutionary based algorithm with a systematic branching strategy. This approach allows an efficient exploration of complex solution domains by automatically balancing local convergence and global search. A number of difficult multiple gravity-assist trajectory design cases demonstrates the effectiveness of the proposed methodology.
Focus on Land in Africa Brief: Mozambique. Lesson 4: Securing Women's Land Rights Requires not only Legal Measures, but also Broad Awareness of Women's Land Rights, Processes that are Inclusive of Women, Enforcement of their Rights, and Efforts to Reshape Discriminatory Practices
Creators: name: Knox, Anna
name: Tanner, Christopher
Publisher: name: Gates Open Research
Year: 2019

description: Focus on Land in Africa Brief: Mozambique. Lesson 4: Securing Women's Land Rights Requires not only Legal Measures, but also Broad Awareness of Women's Land Rights, Processes that are Inclusive of Women, Enforcement of their Rights, and Efforts to Reshape Discriminatory Practices
Synthesis, characterization, powder X-ray diffraction analysis, thermal stability, antioxidant properties and enzyme inhibitions of M(II)-Schiff base ligand complexes
Creators: name: Buldurun, Kenan
name: Turan, Nevin
name: Bursal, Ercan
name: Aras, Abdulmelik
name: Mantarcı, Asim
name: Çolak, Naki
name: Türkan, Fikret
name: Gülçin, İlhami
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: The Schiff base ligand ((E)-6-methyl-2-(2,3,4-trimethoxybenzylideneamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile) and its cobalt(II) and palladium(II) complexes were successfully prepared. The structure of the compounds was elucidated by various techniques (NMR, FT-IR, powder X-ray diffraction, microanalysis, TGA, magnetic susceptibility, mass spectrometry). The Pd(II) complex showed a square planar geometry and the Co(II) complex had an octahedral geometry. ABTS (2,2-azino-bis 3-ethylbenzothiazloine-6-sulphonic acid), DPPH (1,1-diphenyl-2-picrylhydrazyl), FRAP (ferric-reducing antioxidant power) and CUPRAC (cupric reducing antioxidant capacity) in vitro methods were applied to identify the antioxidant features of the synthesized compounds. In addition, glutathione S-transferase and acetyl/butyryl cholinesterase enzymes were examined for possible inhibition capacities of the complexes. According to the enzyme activity measurements, Ru(II) complex inhibited both GST and BChE enzymes, while Fe(II) complex inhibited only AChE enzyme. Furthermore, the antioxidant activities and enzyme inhibitions of the previously synthesized Fe(II) and Ru(II) complexes of the same ligand were examined to make a comparison of the metal complexes. Communicated by Ramaswamy H. Sarma
Interference Channel with a Half-Duplex Out-of-Band Relay
Creators: name: Sahin, Onur
name: Simeone, Osvaldo
name: Erkip, Elza
Publisher: name: arXiv
Year: 2010
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: A Gaussian interference channel (IC) aided by a half-duplex relay is considered, in which the relay receives and transmits in an orthogonal band with respect to the IC. The system thus consists of two parallel channels, the IC and the channel over which the relay is active, which is referred to as Out-of-Band Relay Channel (OBRC). The OBRC is operated by separating a multiple access phase from the sources to the relay and a broadcast phase from the relay to the destinations. Conditions under which the optimal operation, in terms of the sum-capacity, entails either signal relaying and/or interference forwarding by the relay are identified. These conditions also assess the optimality of either separable or non-separable transmission over the IC and OBRC. Specifically, the optimality of signal relaying and separable coding is established for scenarios where the relay-to-destination channels set the performance bottleneck with respect to the source-to-relay channels on the OBRC. Optimality of interference forwarding and non-separable operation is also established in special cases.
description: 5 pages, 5 figures, to appear in Proceedings of IEEE ISIT 2010
Ein gesprech des Teütschen Lands, vnd der hoffnung, dise gegenwertige Kriegsleüff betreffend : jn Welschland beschriben vnd hernach welscher sprach verteütschet
Creators: name: (:Null)
Publisher: name: [Strassburg] : [Jakob Frölich]
Year: 2016

description: Title page features framed woodblock engraving of two men (one face-less) meeting with a tree in centre position.
Breaking of de Sitter Symmetry
Creators: name: Bander, Myron
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We show that an interacting spin-0 field on a de Sitter space background will break the underlying de Sitter symmetry. This is done first for a (1+1) de Sitter space where a boson-fermion correspondence permits us to solve certain interacting theories by transforming them into free ones of opposite statistics. A massless boson interacting by a sine-Gordon potential is shown to be equivalent to a free massive fermion with the mass depending on the de Sitter time thus breaking the symmetry explicitly. We then show that for larger dimensions and any boson potential, to one loop, an anomaly develops and the currents generating the de Sitter transformations are not conserved.
description: Talk at Quarks, Strings and the Cosmos - H\'{e}ctor Rubinstein Memorial Symposium, August 09-11, 2010 AlbaNova)Stockholm) Sweden 12 pages, 1 figure
Measurement and animation of the eye region of the human face in reduced coordinates
Creators: name: Neog, Debanga Raj
Publisher: name: University of British Columbia
Year: 2018

description: The goal of this dissertation is to develop methods to measure, model, and animate facial tissues of the region around the eyes, referred to as the eye region. First, we measure the subtle movements of the soft tissues of the eye region using a monocular RGB-D camera setup, and second, we model and animate these movements using parameterized motion models. The muscles and skin of the eye region are very thin and sheetlike. By representing these tissues as thin elastic sheets in reduced coordinates, we have shown how we can measure and animate these tissues efficiently. To measure tissue movements, we optically track both eye and skin motions using monocular video sequences. The key idea here is to use a reduced coordinates framework to model thin sheet-like facial skin of the eye region. This framework implicitly constrains skin to conform to the shape of the underlying object when it slides. The skin configuration can then be efficiently reconstructed in 3D by tracking two dimensional skin features in video. This reduced coordinates model allows interactive real-time animation of the eye region in WebGL enabled devices using a small number of animation parameters, including gaze. Additionally, we have shown that the same reduced coordinates framework can also be used for physics-based simulation of the facial tissue movements and to produce tissue deformations that occur in facial expressions. We validated our skin measurement and animation algorithms using skin movement sequences with known skin motions, and we can recover skin sliding motions with low reconstruction errors. We also propose an image-based algorithm that corrects accumulated inaccuracy of standard 3D anatomy registration systems that occurs during motion capture, anatomy transfer, image generation, and animation. After correction, we can overlay the anatomy on input video with low misalignment errors for augmented reality applications, such as anatomy mirroring. Our results show that the proposed image-based corrective registration can effectively reduce these inaccuracies.
Molecular modeling studies of novel naphthyridine and isoquinoline derivatives as CDK8 inhibitors
Creators: name: Li, Qunlin
name: Feng, Kairui
name: Liu, Jianxin
name: Ren, Yujie
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Cell cycle is an important part of cellular activities. The selective inhibition of cyclin-dependent kinases (CDK) activity in tumor cells can lead to continuous cell proliferation. Thirty-nine CDK8 inhibitors were systematically investigated on the basis of a three-dimensional quantitative structure–activity relationship (3D-QSAR). Models for comparative molecular field analysis (q2=0.64, r2=0.98) and comparative molecular similarity index analysis (q2=0.609, r2=0.952) were obtained. Contour maps illustrated that bioactivity of inhibitors is most affected by steric, electrostatic, hydrogen bond donor, and receptor interactions of molecular groups. Twenty new CDK8 inhibitors (DS01–DS20) were designed based on the contour maps. The results of ADME prediction illustrated that the designed compounds had potential druggability. The binding mode between a ligand and receptor was explored through molecular docking and molecular dynamics. Results revealed that the hydrogen bond interaction with residue LYS52 remarkably affected the activity of these compounds. Further analysis indicated that the introduction of fluorine to an amino naphthyridine ring of compound 28 contributes to the improvement of molecular activities. Pharmacophore-based virtual screening and Surflex-Sim in the ZINC database of 1,30,000 molecules demonstrated that 14 compounds with an indazole ring might be antitumor inhibitors. 3D-QSAR, molecular docking, molecular dynamics and pharmacophore results are consistent. These findings can be used as a reference for the design and discovery of new CDK8 inhibitors that can reduce design errors. Communicated by Ramaswamy H. Sarma
Azimuthal correlation of gluon jets created in proton-antiproton annihilation
Creators: name: Kuraev, E. A.
name: Bytev, V. V.
name: Kokoulina, E. S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Annihilation process of proton and antiproton to guark antiquark pair accompanied by emission of two additional gluon jets with intermediate state of vector meson is considered.Strong azimuthal correlation is revealed of two gluonic jets,effectively created in the same plane.Some applications to cosmic ray events and to LHC experiments are discussed.
description: 7 pages, 4 figures
Direct Gauge Mediation of Uplifted Metastable Supersymmetry Breaking in Supergravity
Creators: name: Maru, Nobuhito
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We propose a direct gauge mediation model based on an uplifted metastable SUSY breaking coupled to supergravity. A constant superpotential plays an essential role to fix the moduli as well as breaking SUSY and R-symmetry and the cancellation of the cosmological constant. Gaugino masses are generated at leading order of SUSY breaking scale, and comparable to the sfermion masses as in the ordinary gauge mediation. Landau pole problem for QCD coupling can be easily solved since more than half of messengers become superheavy, which are heavier than the GUT scale.
description: 14 pages, 2 figures, references added
The relationships between rapid urban development and vegetation in the pan Pacific region : spatio-temporal quantification using satellite images
Creators: name: Lu, Yuhao
Publisher: name: University of British Columbia
Year: 2018

description: Cities strive for economic strength while recognize the necessity of being environmentally sustainable. The balance between economic development and the environment has been challenging particularly for cities in the pan Pacific region, which is seeing some of the most rapid urban growth rates. Remotely sensed satellite images offer much larger and more consistent spatial and temporal coverages than conventional census data therefore are increasingly being utilized for regional and global urban studies. Two key remote sensing datasets, namely urban vegetation cover derived from Landsat time series, and brightness generated from NOAA’s nighttime lights datasets to represent urban development were the focus of this dissertation. I first extracted annual urban vegetation characteristics using spectral indices (e.g. EVI) as well as a spectral mixture analysis from 1984 to 2012. Nighttime lights brightness was used to assess urban expansion and its relationship with census-derived variables. Lastly, I examined the relationships between urban development and the environment using Environment Kuznets Curve (EKC) theory as a lens, addressing how urban vegetation responds to urban nighttime brightness in 25 cities across the pan Pacific region. I identified inter- and intra-city patterns of vegetation and brightness changes that were strongly related to social and economic contexts. Spectral indices demonstrated opposing trends between urban vegetation and built-up area both spatially and temporally. Spectral mixture analysis successfully extracted the urban vegetation fraction at a sub-pixel level, setting a robust base for cross-city comparisons. I found that urban vegetation changed linearly both positively and negatively with urban brightness, particularly in higher income cities in North America. Pixels with statistically strong quadratic relationships between vegetation and brightness were less prevalent but more spatially clustered in comparison to those that expressed a linear relationship. Overall, there are three key contribution of this dissertation. Firstly, the integration of gap-free satellite images and innovative processing techniques unlocked new ways of informing urban environmental and socio-economic dynamics. Secondly, a classic econometric model (i.e. Granger causality test) was used to examine the casual relationship between census and remote sensing nighttime lights data. Lastly, a pixel-based model fitting was use to confirm EKC at a sub-city scale.
The Environmental Dependence of Galaxy Properties at z=2
Creators: name: Tanaka, Masayuki
name: De Breuck, Carlos
name: Venemans, Bram
name: Kurk, Jaron
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report on the environmental dependence of galaxy properties at z=2.15. We construct multi-band photometric data sets in the (proto-)cluster PKS1138-26 field and in the GOODS field. We then fit spectral energy distributions of the galaxies with model templates generated with the latest stellar population synthesis code and derive physical properties of galaxies from the fits. To quantify the environmental dependence of galaxy properties, a special care is taken of systematic errors -- we use data sets that have almost the same wavelength samplings, use the same code to fit SEDs with the same set of templates, and compare relative differences between the two samples. We find that the PKS1138 galaxies have similar ages, shorter star formation time scales, lower star formation rates, and weaker dust extinction compared to the GOODS galaxies at z~2. This trend is similar to that observed locally, suggesting that the environmental dependence of galaxy properties is already partly in place as early as z=2.15. We show that the PKS1138 galaxies assemble the bulk of their masses ~1 Gyr earlier than field galaxies, i.e., the galaxy formation depends on environment. Galaxy mergers should frequently occur during the first collapse of clusters and they might play an important role in driving the observed environmental dependence of galaxy properties at z=2.15.
description: 15 pages, 15 figures, accepted for publication in A&A.
การพัฒนาระบบสารสนเทศสำหรับผู้บริหารสถาบันการอาชีวศึกษา สังกัดสำนักงานคณะกรรมการการอาชีวศึกษา
Creators: name: พิมลพรรณ เพชรสมบัติ
Publisher: name: มหาวิทยาลัยมหาจุฬาลงกรณราชวิทยาลัย วิทยาเขตนครสวรรค์
Year: 2023
Subjects: การพัฒนา
ระบบสารสนเทศ
ผู้บริหาร
สถาบันการอาชีวศึกษา

description: The Journal of Research and Academics, 6, 3, 229-240