Additional file 1 of Association of air pollution exposure and increased coronary artery disease risk: the modifying effect of genetic susceptibility
Creators: name: Fu, Zuqiang
name: Ma, Yuanyuan
name: Yang, Changjie
name: Liu, Qian
name: Liang, Jingjia
name: Weng, Zhenkun
name: Li, Wenxiang
name: Zhou, Shijie
name: Chen, Xiu
name: Xu, Jin
name: Xu, Cheng
name: Huang, Tao
name: Zhou, Yong
name: Gu, Aihua
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Developmental Biology
subject: Science Policy
subject: Virology

description: Additional file 1: Figure S1. Correlation heatmap of air pollutant exposures calculated using data from 447,530 samples. Figure S2. Kaplan‒Meier curve for the incidence of coronary artery disease in individuals exposed to PM2.5 with quartiles of concentrations. Figure S3. Kaplan‒Meier curve for the incidence of coronary artery disease in individuals exposed to PM2.5-10 with quartiles of concentrations. Figure S4. Kaplan‒Meier curve for the incidence of coronary artery disease in individuals exposed to PM10 with quartiles of concentrations. Figure S5. Kaplan‒Meier curve for the incidence of coronary artery disease in individuals exposed to NO2 at quartiles of concentrations. Figure S6. Kaplan‒Meier curve for the incidence of coronary artery disease in individuals exposed to NOx at quartiles of concentrations. Figure S7. Association between air pollution concentration and the risk of CAD. Table S1. Code list of coronary artery disease in the UK Biobank. Table S2. The main information on genetic variants associated with coronary artery disease in the UK Biobank. Table S3. Adjusted hazard ratio and 95% confidence interval of coronary artery disease by air pollution exposure. Table S4. Subgroup analysis for the association of coronary artery disease per 10 μg/m3 increase in air pollutants by specific characteristics. Table S5. Additive joint interaction for included air pollutant exposure and genetic categories on incident coronary artery disease after excluding participants with a follow-up time of less than 2 years in the UK Biobank. Table S6. The joint association of PM2.5 exposure and coronary artery disease PRS with the risk of incident coronary artery disease after excluding participants with a follow-up time of less than 2 years in the UK Biobank. Table S7.The joint association of PM10 exposure and coronary artery disease PRS with the risk of incident coronary artery disease after excluding participants with a follow-up time of less than 2 years in the UK Biobank. Table S8. The joint association of NO2 exposure and coronary artery disease PRS with the risk of incident coronary artery disease after excluding participants with a follow-up time of less than 2 years in the UK Biobank. Table S9. The joint association of NOx exposure and coronary artery disease PRS with the risk of incident coronary artery disease after excluding participants with a follow-up time of less than 2 years in the UK Biobank.