cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(102868) Lancelot Ashley Lewis
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The HIV/SIV Envelope Protein: From Structure To Function To Host Evasion
Creators: name: Swanstrom, R.
name: Joseph, S.B.
Publisher: name: Bentham Science Publishers B.V.
Year: 2018

description: It is a pleasure to write an introduction for this collection of five short reviews of primate lentivirus Env proteins. These are
very timely reviews, each designed to cover a different aspect of the biology of these proteins. This is a remarkable time to
organize what we know about this family of proteins. There has been a long-standing interest in these proteins for their role in
viral entry. The Env protein is the only viral protein on the surface of the virion making it the sole protein involved in entry.
The synthesis of the Env protein is somewhat unremarkable, being a typical type 1 transmembrane protein synthesized as a
large precursor on the rough ER. There is the co-translational addition of carbohydrate within the ER and trimerization of the
Env protein precursor. Then in the golgi, a host protease cleaves the larger precursor into an extracellular surface protein (SU
subunit) and a transmembrane protein (TM subunit), creating a new N terminus of the TM protein that functions as the fusion
peptide in the fusion event. Despite this cleavage event, the SU and TM proteins remain together, with three of each subunit
comprising an Env trimer.
Deterministic algorithms for the Lovasz Local Lemma: simpler, more general, and more parallel
Creators: name: Harris, David G.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences

description: The Lovász Local Lemma (LLL) is a keystone principle in probability theory, guaranteeing the existence of configurations which avoid a collection $\mathcal B$ of "bad" events which are mostly independent and have low probability. In its simplest "symmetric" form, it asserts that whenever a bad-event has probability $p$ and affects at most $d$ bad-events, and $e p d < 1$, then a configuration avoiding all $\mathcal B$ exists. A seminal algorithm of Moser & Tardos (2010) gives nearly-automatic randomized algorithms for most constructions based on the LLL. However, deterministic algorithms have lagged behind. We address three specific shortcomings of the prior deterministic algorithms. First, our algorithm applies to the LLL criterion of Shearer (1985); this is more powerful than alternate LLL criteria and also removes a number of nuisance parameters and leads to cleaner and more legible bounds. Second, we provide parallel algorithms with much greater flexibility in the functional form of of the bad-events. Third, we provide a derandomized version of the MT-distribution, that is, the distribution of the variables at the termination of the MT algorithm. We show applications to non-repetitive vertex coloring, independent transversals, strong coloring, and other problems. These give deterministic algorithms which essentially match the best previous randomized sequential and parallel algorithms.
description: This superseded arxiv:1807.06672
Hundreds of new cluster candidates in the VISTA variables in the Via Lactea survey DR1
Creators: name: Barba, R. H.
name: Roman-Lopes, A.
name: Castellon, J. L. Nilo
name: Firpo, V.
name: Minniti, D.
name: Lucas, P.
name: Emerson, J. P.
name: Hempel, M.
name: Soto, M.
name: Saito, R. K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: VISTA variables in the Via Lactea is an ESO Public survey dedicated to scan the bulge and an adjacent portion of the Galactic disk in the fourth quadrant using the VISTA telescope and the near-infrared camera VIRCAM. One of the leading goals of the VVV survey is to contribute to the knowledge of the star cluster population of the Milky Way. To improve the census of the Galactic star clusters, we performed a systematic scan of the JHKs images of the Galactic plane section of the VVV survey. Our detection procedure is based on a combination of superficial density maps and visual inspection of promising features in the NIR images. The material examined are color-composite images corresponding to the DR1 of VVV. We report the discovery of 493 new star cluster candidates. The analysis of the spatial distribution show that the clusters are very concentrated in he Galactic plane, presenting some local maxima around the position of large star-forming complexes, such as G305, RCW 95, and RCW 106. The vast majority of the cluster candidates are quite compact and generally surrounded by bright and/or dark nebulosities. IRAS point sources are associated with 59% of the sample, while 88% are associated with MSX point sources. GLIMPSE 8 mum images of the cluster candidates show a variety of morphologies, with 292 clusters dominated by knotty sources, while 361 clusters show some kind of nebulosity. Spatial cross-correlation with young stellar objects, masers, and extended green-object catalogs suggest that a large sample of the new cluster candidates are extremely young. In particular, 104 star clusters associated to methanol masers are excellent candidates for ongoing massive star formation. Also, there is a special set of sixteen cluster candidates that present clear signspot of star-forming activity having associated simultaneosly dark nebulae, young stellar objects, EGOs, and masers.
description: 13 pages, 8 figures, 3 tables. Accepted in Astronomy and Astrophysics. The full catalog and charts available at http://astro.userena.cl/science/lsclusters.php
title: Radiation Exposure Dose to patient and operator undergoing trans-radial coronary angiography or coronary intervention
Creators: name: Yoon, Sang-Wook
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Interventional vascular
subject: Radiation physics
subject: Radioprotection / Radiation dose
subject: Fluoroscopy
subject: Digital radiography
subject: Catheter arteriography
subject: Angioplasty
subject: Radiation effects
subject: Radiation safety
subject: Quality assurance

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Trans-radial coronary angiography(TRA) or intervention(TRI) is being performed as the safe and effective procedure for the diagnosis and treatment of coronary artery diseases. However, we should concern with the radiation hazard to the patient or...
(102869) Nancy Philips Brookes
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Study on assessment of bladder cancer with muscle layer invasion using Fluid Attenuated Inversion Recovery (FLAIR) Method combined with DWI (FLAIR-DWI)
Creators: name: nitta, Yuki
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Urinary Tract / Bladder
subject: MR-Diffusion/Perfusion
subject: Imaging sequences
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The main role of current MR examination is to investigate the presence or absence of distant metastasis to the lymph nodes and depth of bladder cancer invasion into the muscle layer. Especially in the primary tumor, stage classification, including...
Integrating the HIV-1 assembly/maturation pathway
Creators: name: Swanstrom, R.
name: Potempa, M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: In PNAS, Jurado et al. (1) describe an unexpected
mechanism of action of a new
class of HIV type 1 (HIV-1) integrase
(IN) inhibitors. Several years ago it was
discovered that the HIV-1 IN was targeted
to sites in chromatin by the host
protein lens epithelium-derived growth
factor (LEDGF)/p75 (2). The site of interaction
between IN and LEDGF/p75 was
defined, and inhibitors to block that interaction
were sought and identified.
In PNAS, Jurado et al. (1) show that although
these inhibitors (termed Allosteric
IN inhibitors, or ALLINIs) have some potency
to block steps involved in integration,
their most dramatic effect is to cause the
virus particle to assemble into a noninfectious
structure.
title: A retrospective review of out of hours reporting in a University hospital: the effect of time and seniority on discrepancy rates
Creators: name: Lam, Vincent
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Workforce
subject: Quality assurance
subject: Education and training
subject: Safety
subject: Observer performance
subject: Audit and standards
subject: PACS
subject: CT
subject: Professional issues
subject: Emergency

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of this study was to assess registrar discrepancy rates out of hours at a University hospital - specifically, the influence of trainee seniority, time and shift...
(102864) Gilbert Lewis
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Stakeholder Knowledge and Perceptions of Free-roaming Equids and Their Management at a Western U.S. Land Grant University
Creators: name: Wood, Hollee S
name: Frey, S. Nicole
name: Messmer, Terry A
Publisher: name: Utah State University
Year: 2022

description: The horse (Equus ferus caballus), originally native to North America, became extinct on the continent approximately 10,000 years ago. Horses that migrated from North America to Eurasia across the Bering Strait continued to evolve and were domesticated along with burros (E. asinus). Both species were then transported to the Americas where they were intentionally released or escaped into the wild, forming feral herds. The Wild Free-Roaming Horses and Burros Act of 1971 (WFRHBA) provided federal oversight and protection for feral horses and burros (hereafter, free-roaming equids) that inhabited designated areas on public lands in the western United States. The Bureau of Land Management (BLM) estimated in 2019 that >90,000 free-roaming equids inhabited 29 million ha on 177 designated herd management areas (HMAs). This population estimate exceeds the designated appropriate management level (AML) of 26,785. To provide BLM managers with insights regarding stakeholder knowledge and perceptions about the management of free-roaming equids in a western U.S. state where HMAs exceed AML, in 2020 we surveyed faculty, staff, and students at the state land-grant university (i.e., Utah State University [USU]). We hypothesized that, because the WFRHBA was passed in 1971, older respondents and those with natural resources education would be more informed and supportive of active free-roaming equid management, such as herd reduction. We received 959 responses (response rate of 12.5%) to our survey (i.e., 14% faculty, 14% staff, and 72% students). Most respondents (60%) were unaware of the WFRHBA, and >50% were unaware that free-roaming equids were protected. Over 45% of our respondents were unsure of HMA AML status or population growth rates. Furthermore, most respondents (65%) did not know that free-roaming equids are ecologically considered feral. Older respondents and those with rural backgrounds and natural resources education were more informed. Our results highlight the need for improved outreach and communication efforts regarding the issues and consequences of free-roaming equid management approaches.
title: Embolization therapy of spontaneous gastrointestinal bleeding in three left ventricular assist device patients.
Creators: name: Todisco, Matteo
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Embolisation
subject: Diagnostic procedure
subject: Fluoroscopy
subject: CT-Angiography
subject: Catheter arteriography
subject: Interventional vascular
subject: Gastrointestinal tract
subject: Emergency
subject: Haemorrhage

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of this study is to validate the effectiveness of arterial embolization in patients with continuous flow left ventricular assist devices (CF-LVAD) and gastrointestinal bleeding(GIB). Antiplatlet, anticoagulant therapy, hemodinamic...
title: Wyoming’s Wild Horse Ranch: History and Description of a Socio-Ecological Experiment
Creators: name: Sas-Jaworsky, Alex
name: Scasta, John Derek
Publisher: name: Utah State University
Year: 2022

description: The growing population of free-roaming horses (Equus ferus caballus) on western public rangelands has necessitated that federal agencies, such as the Bureau of Land Management (BLM) and U.S. Forest Service, develop novel approaches to curb growth including reproduction management. However, bureaucracy has hindered effective research and application of horse management on public lands and examples on private lands may present new solutions. Here we present the history and current population management strategy for the Wild Horse Ranch (WHR) located in southeastern Wyoming, USA, as an example of an ongoing private entity managing horses. Prior to 1985, this ~6,000-ha ranch was used historically for domestic sheep (Ovis aries) production, and after 1985, for yearling cattle (Bos taurus). In 2005, geldings (i.e., castrated males) and mares were purchased from BLM by WHR and introduced to the ranch in conjunction with the development of home sites. In 2019, landowners formed the Wild Horse Preservation Society (WHPS) to enhance horse management and care. The WHPS uses multiple approaches to manage population growth including castrating stallions and treating mares with chemical contraception through partnerships with veterinarians and other stakeholders. In addition, WHPS feeds supplemental hay to horses in severe winter months, provides water during the summer, monitors rangeland vegetation, horse diets, and cares for abandoned foals or geriatric horses. The WHPS is a network of board members and landowners that is working for the betterment of horse welfare and rangeland health and is situated to be a leading entity and example in the area of free-enterprise free-roaming horse reproduction management.
A Note on the Convergence of ADMM for Linearly Constrained Convex Optimization Problems
Creators: name: Chen, Liang
name: Sun, Defeng
name: Toh, Kim-Chuan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 65K05, 90C25, 90C46

description: This note serves two purposes. Firstly, we construct a counterexample to show that the statement on the convergence of the alternating direction method of multipliers (ADMM) for solving linearly constrained convex optimization problems in a highly influential paper by Boyd et al. [Found. Trends Mach. Learn. 3(1) 1-122 (2011)] can be false if no prior condition on the existence of solutions to all the subproblems involved is assumed to hold. Secondly, we present fairly mild conditions to guarantee the existence of solutions to all the subproblems and provide a rigorous convergence analysis on the ADMM, under a more general and useful semi-proximal ADMM (sPADMM) setting considered by Fazel et al. [SIAM J. Matrix Anal. Appl. 34(3) 946-977 (2013)], with a computationally more attractive large step-length that can even exceed the practically much preferred golden ratio of $(1+\sqrt{5})/2$.
description: 11 pages, 2 figures
Resolving the Degeneracy in Single Higgs Production with Higgs Pair Production
Creators: name: Cao, Qing-Hong
name: Yan, Bin
name: Zhang, Dong-Ming
name: Zhang, Hao
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The Higgs boson production can be affected by several anomalous couplings, e.g. $c_t$ and $c_g$ anomalous couplings. Precise measurement of $gg\to h$ production yields two degenerate parameter spaces of $c_t$ and $c_g$; one parameter space exhibits the SM limit while the other does not. Such a degeneracy could be resolved by Higgs boson pair production. In this work we adapt the strategy suggested by the ATLAS collaboration to explore the potential of distinguishing the degeneracy at the 14 TeV LHC. If the $c_t$ anomalous coupling is induced only by the operator $H^†H \bar Q_L \tilde{H} t_R$, then the non-SM-like band could be excluded with an integrated luminosity of $\sim 235~{\rm fb}^{-1}$. Making use of the fact that the Higgs boson pair is mainly produced through an $s$-wave scattering, we propose an analytical function to describe the fraction of signal events surviving a series of experimental cuts for a given invariant mass of Higgs boson pair. The function is model independent and can be applied to estimate the discovery potential of various NP models.
RNA-dependent RNA polymerase speed and fidelity are not the only determinants of the mechanism or efficiency of recombination
Creators: name: Cameron, C.E.
name: Kim, H.
name: Ellis, V.D., III
name: Ellis, V.D., III
name: Zhao, Y.
name: Arnold, J.J.
name: Zhao, Y.
name: Kim, H.
name: Cameron, C.E.
name: Arnold, J.J.
name: Woodman, A.
name: Woodman, A.
Publisher: name: MDPI AG
Year: 2019

description: Using the RNA-dependent RNA polymerase (RdRp) from poliovirus (PV) as our model system, we have shown that Lys-359 in motif-D functions as a general acid in the mechanism of nucleotidyl transfer. A K359H (KH) RdRp derivative is slow and faithful relative to wild-type enzyme. In the context of the KH virus, RdRp-coding sequence evolves, selecting for the following substitutions: I331F (IF, motif-C) and P356S (PS, motif-D). We have evaluated IF-KH, PS-KH, and IF-PS-KH viruses and enzymes. The speed and fidelity of each double mutant are equivalent. Each exhibits a unique recombination phenotype, with IF-KH being competent for copy-choice recombination and PS-KH being competent for forced-copy-choice recombination. Although the IF-PS-KH RdRp exhibits biochemical properties within twofold of wild type, the virus is impaired substantially for recombination in cells. We conclude that there are biochemical properties of the RdRp in addition to speed and fidelity that determine the mechanism and efficiency of recombination. The interwoven nature of speed, fidelity, the undefined property suggested here, and recombination makes it impossible to attribute a single property of the RdRp to fitness. However, the derivatives described here may permit elucidation of the importance of recombination on the fitness of the viral population in a background of constant polymerase speed and fidelity.
Charged Black Hole Solutions in Gauss-Bonnet-Massive Gravity
Creators: name: Hendi, S. H.
name: Panahiyan, S.
name: Panah, B. Eslam
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Motivated by high interest in the close relation between string theory and black hole solutions, in this paper, we take into account the Einstein-Gauss-Bonnet Lagrangian in the context of massive gravity. We examine the possibility of black hole in this regard, and discuss the types of horizons. Next, we calculate conserved and thermodynamic quantities and check the validity of the first law of thermodynamics. In addition, we investigate the stability of these black holes in context of canonical ensemble. We show that number, type and place of phase transition points may be significantly affected by different parameters. Next, by considering cosmological constant as thermodynamical pressure, we will extend phase space and calculate critical values. Then, we construct thermodynamical spacetime by considering mass as thermodynamical potential. We study geometrical thermodynamics of these black holes in context of heat capacity and extended phase space. We show that studying heat capacity, geometrical thermodynamics and critical behavior in extended phase space lead to consistent results. Finally, we will employ a new method for obtaining critical values and show that the results of this method are consistent with those of other methods.
description: Revised version: 22 pages, 18 figures
Dynamic Subgoal-based Exploration via Bayesian Optimization
Creators: name: Wang, Yijia
name: Poloczek, Matthias
name: Jiang, Daniel R.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Optimization and Control (math.OC)
subject: Machine Learning (cs.LG)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: Reinforcement learning in sparse-reward navigation environments with expensive and limited interactions is challenging and poses a need for effective exploration. Motivated by complex navigation tasks that require real-world training (when cheap simulators are not available), we consider an agent that faces an unknown distribution of environments and must decide on an exploration strategy. It may leverage a series of training environments to improve its policy before it is evaluated in a test environment drawn from the same environment distribution. Most existing approaches focus on fixed exploration strategies, while the few that view exploration as a meta-optimization problem tend to ignore the need for cost-efficient exploration. We propose a cost-aware Bayesian optimization approach that efficiently searches over a class of dynamic subgoal-based exploration strategies. The algorithm adjusts a variety of levers -- the locations of the subgoals, the length of each episode, and the number of replications per trial -- in order to overcome the challenges of sparse rewards, expensive interactions, and noise. An experimental evaluation demonstrates that the new approach outperforms existing baselines across a number of problem domains. We also provide a theoretical foundation and prove that the method asymptotically identifies a near-optimal subgoal design.
PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions
Creators: name:  Cremer, P.S.
name: Shengjuler, D.
name:  Cameron, C.E.
name:  Cremer, P.S.
name:  Sun, S.
name: Shengjuler, D.
name:  Cameron, C.E.
name:  Sun, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Numerous cellular proteins interact with membrane surfaces to affect essential cellular processes. These interactions can be directed towards a specific lipid component within a membrane, as in the case of phosphoinositides (PIPs), to ensure specific subcellular localization and/or activation. PIPs and cellular PIP-binding domains have been studied extensively to better understand their role in cellular physiology. We applied a pH modulation assay on supported lipid bilayers (SLBs) as a tool to study protein-PIP interactions. In these studies, pH sensitive ortho-Sulforhodamine B conjugated phosphatidylethanolamine is used to detect protein-PIP interactions. Upon binding of a protein to a PIP-containing membrane surface, the interfacial potential is modulated (i.e. change in local pH), shifting the protonation state of the probe. A case study of the successful usage of the pH modulation assay is presented by using phospholipase C delta1 Pleckstrin Homology (PLC-δ1 PH) domain and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) interaction as an example. The apparent dissociation constant (Kd,app) for this interaction was 0.39 ± 0.05 µM, similar to Kd,app values obtained by others. As previously observed, the PLC-δ1 PH domain is PI(4,5)P2 specific, shows weaker binding towards phosphatidylinositol 4-phosphate, and no binding to pure phosphatidylcholine SLBs. The PIP-on-a-chip assay is advantageous over traditional PIP-binding assays, including but not limited to low sample volume and no ligand/receptor labeling requirements, the ability to test high- and low-affinity membrane interactions with both small and large molecules, and improved signal to noise ratio. Accordingly, the usage of the PIP-on-a-chip approach will facilitate the elucidation of mechanisms of a wide range of membrane interactions. Furthermore, this method could potentially be used in identifying therapeutics that modulate protein's capacity to interact with membranes.
A coronagraphic absorbing cloud reveals the narrow-line region and extended Lyman-$α$ emission of QSO J0823+0529
Creators: name: Fathivavsari, Hassan
name: Petitjean, Patrick
name: Noterdaeme, Pasquier
name: Pâris, Isabelle
name: Finley, Hayley
name: López, Sebastian
name: Srianand, Raghunathan
name: Sánchez, Paula
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report long-slit spectroscopic observations of the quasar SDSS J082303.22+052907.6 ($z_{\rm CIV}$$\sim$3.1875), whose Broad Line Region (BLR) is partly eclipsed by a strong damped Lyman-$α$ (DLA; log$N$(HI)=21.7) cloud. This allows us to study the Narrow Line Region (NLR) of the quasar and the Lyman-$α$ emission from the host galaxy. Using CLOUDY models that explain the presence of strong NV and PV absorption together with the detection of SiII$^*$ and OI$^{**}$ absorption in the DLA, we show that the density and the distance of the cloud to the quasar are in the ranges 180 $$ $r_0$ $>$230 pc, respectively. Sizes of the neutral($\sim$2-9pc) and highly ionized phases ($\sim$3-80pc) are consistent with the partial coverage of the CIV broad line region by the CIV absorption from the DLA (covering factor of $\sim$0.85). We show that the residuals are consistent with emission from the NLR with CIV/Lyman-$α$ ratios varying from 0 to 0.29 through the profile. Remarkably, we detect extended Lyman-$α$ emission up to 25kpc to the North and West directions and 15kpc to the South and East. We interpret the emission as the superposition of strong emission in the plane of the galaxy up to 10kpc with emission in a wind of projected velocity $\sim$500kms$^{-1}$ which is seen up to 25kpc. The low metallicity of the DLA (0.27 solar) argues for at least part of this gas being in-falling towards the AGN and possibly being located where accretion from cold streams ends up.
description: Accepted for publication in MNRAS, 14 pages, 13 figures, 4 tables
title: Review iodinated contrast media: Classification, adverse reactions, interactions with other drugs and special situations.
Creators: name: Ramos Solis, Maria Fatima
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Contrast agents
subject: Management
subject: CT
subject: CT-Angiography
subject: Contrast agent-intravenous
subject: Drugs / Reactions
subject: Toxicity

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Review the classification of iodinated contrast. Describe adverse reactions according to their cause, severity and by time of presentation. Show its treatment and prevention. Describe contrast induced nephropathy and intravenous contrast...
(102865) Essington Lewis
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Renal interventions : A resident's guide.
Creators: name: Nadarajan, Sreeraj
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Interventional vascular
subject: Interventional non-vascular
subject: CT
subject: Ultrasound
subject: Catheter arteriography
subject: Angioplasty
subject: Embolisation
subject: Drainage
subject: Aneurysms
subject: Arteriovenous malformations
subject: Abscess

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The purpose of thiseducational exhibit is to : Detail the vascular and non vascular renal interventions that can be performed by interventional radiologists. Illustrate the techniques of various renal interventions with relevant case examples from...
title: MRI features of Brain in Young Adults with Dengue Encephalopathy.
Creators: name: Sirasapalli, Chinnam
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: CNS
subject: MR
subject: Health policy and practice
subject: Epidemiology

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Dengue is the most rapidly spreading tropical and sub-tropical arboviral disease in the world with30-fold increase in its incidence in the last 50 years, increasing geographic expansion to new countries and increasingmortality rates[1]. We have come...
title: CT-Guided Hook Wire Localisation of Lung Lesions for Video-Assisted Thoracoscopic Surgery - A Single Centre Experience
Creators: name: Ip, Siu Kwan Natalie
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Lung
subject: Interventional non-vascular
subject: Thorax
subject: CT
subject: Localisation
subject: Neoplasia
subject: Cancer
subject: Metastases

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Hook wire localisation has already been widely adopted for management of breast nodules.It is also advantageous for pre-operative localisation of pulmonary lesions. In this report, wedescribe and evaluate our experience using spiral wire for...
Nonlinear neutrino-photon interactions inside strong laser pulses
Creators: name: Meuren, Sebastian
name: Keitel, Christoph H.
name: Di Piazza, Antonino
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Even though neutrinos are neutral particles and interact only via the exchange of weak gauge bosons, charged leptons and quarks can mediate a coupling to the photon field beyond tree level. Inside a relativistically strong laser field nonlinear effects in the laser amplitude can play an important role, as electrons and positrons interact nonperturbatively with the coherent part of the photon field. Here, we calculate for the first time the leading-order contribution to the axial-vector--vector current-coupling tensor inside an arbitrary plane-wave laser field (which is taken into account exactly by employing the Furry picture). The current-coupling tensor appears in the calculation of various electroweak processes inside strong laser fields like photon emission or trident electron-positron pair production by a neutrino. Moreover, as we will see below, the axial-vector--vector current-coupling tensor contains the Adler-Bell-Jackiw (ABJ) anomaly. This occurrence renders the current-coupling tensor also interesting from a fundamental point of view, as it is the simplest Feynman diagram in an external field featuring this kind of anomaly.
description: 18 pages, 4 figures
Native Tertiary Structure and Nucleoside Modifications Suppress tRNA's Intrinsic Ability to Activate the Innate Immune Sensor PKR
Creators: name: Jones, C.N.
name: Sharma, S.D.
name: Cameron, C.E.
name: Bevilacqua, P.C.
name: Cameron, C.E.
name: Nallagatla, S.R.
name: Spremulli, L.L.
name: Nallagatla, S.R.
name: Sharma, S.D.
name: Ghosh, S.K.B.
name: Ghosh, S.K.B.
name: Jones, C.N.
name: Bevilacqua, P.C.
name: Spremulli, L.L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Interferon inducible protein kinase PKR is an essential component of innate immunity. It is activated by long stretches of dsRNA and provides the first line of host defense against pathogens by inhibiting translation initiation in the infected cell. Many cellular and viral transcripts contain nucleoside modifications and/or tertiary structure that could affect PKR activation. We have previously demonstrated that a 5′-end triphosphate-a signature of certain viral and bacterial transcripts-confers the ability of relatively unstructured model RNA transcripts to activate PKR to inhibit translation, and that this activation is abrogated by certain modifications present in cellular RNAs. In order to understand the biological implications of native RNA tertiary structure and nucleoside modifications on PKR activation, we study here the heavily modified cellular tRNAs and the unmodified or the lightly modified mitochondrial tRNAs (mt-tRNA). We find that both a T7 transcript of yeast tRNAPhe and natively extracted total bovine liver mt-tRNA activate PKR in vitro, whereas native E. coli, bovine liver, yeast, and wheat tRNAPhe do not, nor do a variety of base- or sugar-modified T7 transcripts. These results are further supported by activation of PKR by a natively folded T7 transcript of tRNAPhe in vivo supporting the importance of tRNA modification in suppressing PKR activation in cells. We also examine PKR activation by a T7 transcript of the A14G pathogenic mutant of mt-tRNALeu, which is known to dimerize, and find that the misfolded dimeric form activates PKR in vitro while the monomeric form does not. Overall, the in vitro and in vivo findings herein indicate that tRNAs have an intrinsic ability to activate PKR and that nucleoside modifications and native RNA tertiary folding may function, at least in part, to suppress such activation, thus serving to distinguish self and non-self tRNA in innate immunity.
Dropshipping - a new business revolution
Creators: name: Kaluzhsky, Mikhail
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: Article about the new form of trade in a network the Internet. Advantages of dropshipping open to the Russian manufacturers and businessmen new horizons in international trade and marketing. The author considers features of evolution and a role of dropshipping in electronic commerce of a new millennium.
description: 11 pages, in Russian. ISSN 0131-7652
Electromagnetism in Curved Spacetimes: Coupling of the Doppler and Gravitational Redshifts
Creators: name: Bunney, Cameron R. D.
name: Gradoni, Gabriele
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We present the basic prerequisites of electromagnetism in flat spacetime and provide the description of electromagnetism in terms of the Faraday tensor. We generalise electromagnetic theory to a general relativistic setting, introducing the Einstein field equations to describe the propagation of electromagnetic radiation in curved space-time. We investigate gravitational redshift and derive formulae for the combined effect of gravitational redshift and the Doppler shift in curved spacetime.
description: 11 pages, 4 figures; v4 typos corrected. In previous versions, the emitted and observed frequencies were mislabelled in the section "Gravitational Redshift."
title: First clinical results of a fusion prototype for mammography and three-dimensional ultrasound with a standard mammography system and a standard ultrasound probe
Creators: name: Schulz-Wendtland, Rüdiger
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Screening
subject: Localisation
subject: Diagnostic procedure
subject: Ultrasound
subject: Mammography
subject: Experimental
subject: Ultrasound physics
subject: Oncology
subject: Breast
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The sensitivity of mammography based breast screening is approximately 60-80%. However, in subgroups, such as women with a high mammographic density, the sensitivity is rather poor and averages 38 to 48 %. For such women the addition of ultrasound...
Human immunodeficiency virus, type 1 protease substrate specificity is limited by interactions between substrate amino acids bound in adjacent enzyme subsites
Creators: name: Copeland, T.
name: Cameron, J.
name: Leis, J.
name: Cameron, J.
name: Wlodawer, A.
name: Weber, I.T.
name: Harrison, R.W.
name: Leis, J.
name: Cameron, C.E.
name: Cameron, C.E.
name: Wlodawer, A.
name: Weber, I.T.
name: Harrison, R.W.
name: Ridky, T.W.
name: Copeland, T.
name: Ridky, T.W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: The specificity of the retroviral protease is determined by the ability of substrate amino acid side chains to bind into eight individual subsites within the enzyme. Although the subsites are able to act somewhat independently in selection of amino acid side chains that fit into each pocket, significant interactions exist between individual subsites that substantially limit the number of clearable amino acid sequences. The substrate peptide binds within the enzyme in an extended anti-parallel β sheet conformation with substrate amino acid side chains adjacent in the linear sequence extending in opposite directions in the enzyme-substrate complex. From this geometry, we have defined both cis and trans steric interactions, which have been characterized by a steady state kinetic analysis of human immunodeficiency virus, type-1 protease using a series of peptide substrates that are derivatives of the avian leukosis/sarcoma virus nucleocapsid-protease cleavage site. These peptides contain both single and double amino acid substitutions in seven positions of the minimum length substrate required by the retroviral protease for specific and efficient cleavage. Steady state kinetic data from the single amino acid substituted peptides were used to predict effects on protease-catalyzed cleavage of corresponding double substituted peptide substrates. The calculated Gibbs' free energy changes were compared with actual experimental values in order to determine how the fit of a substrate amino acid in one subsite influences the fit of amino acids in adjacent subsites. Analysis of these data shows that substrate specificity is limited by steric interactions between pairs of enzyme subsites. Moreover, certain enzyme subsites are relatively tolerant of substitutions in the substrate and exert little effect on adjacent subsites, whereas others are more restrictive and have marked influence on adjacent cis and trans subsites.
Tabella oder Etat : Der Sæmmtlich Chur Fürstl. Sæchsischen Trouppen, wie Solche a[nn]o. 1766 effèctive bestehen. Mit Vorzeichnung eines jeden Regiments dermahligen Uniforme, und Garnisons, auch mit mehrern Anmerkungen erläutert.
Creators: name: (:Unkn) Unknown
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1766
Subjects: subject: Sachsen
subject: 090

description: Sächsisches Truppenverzeichnis 1766
A Positive Mass Theorem for Static Causal Fermion Systems
Creators: name: Finster, Felix
name: Platzer, Andreas
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mathematical Physics (math-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Differential Geometry (math.DG)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Asymptotically flat static causal fermion systems are introduced. Their total mass is defined as a limit of surface layer integrals which compare the measures describing the asymptotically flat spacetime and a vacuum spacetime near spatial infinity. Our definition does not involve any regularity assumptions; it even applies to singular or generalized "quantum" spacetimes. A positive mass theorem is proven. Our methods and results explain why and how the causal action principle incorporates the nonlinear effects of gravity for static systems.
description: 57 pages, LaTeX, 3 figures, sign errors in (6.5) and (6.9) corrected, footnote on page 43 added
title: The evaluation of the cyst and cyst-like lesions of knee joint with MRI in patients with and without knee osteoarthritis
Creators: name: Gulseren, Yildiz
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Musculoskeletal joint
subject: Musculoskeletal system
subject: MR
subject: Screening
subject: Cysts
subject: Arthritides

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Osteoarthritis(OA) is a progressive, chronic disease that causes subchondral sclerosis, marginal osteophytes and cartilage damage (1) . Arthralgia, movement restriction and functional loss arethe most common symptoms. OA is often encountered in...
Αδελφότης Εργατών Τυπογράφων «η Πρόοδος» και η απόπειρα ίδρυσης νέου Πρακτορείου διακίνησης εντύπων (1898)
Creators: name: Ζαζάς, Δημήτρης
Publisher: name: δοκιμές, Επιθεώρηση Κοινωνικών Σπουδών // dokimes, Review of Social Studies
Year: 2023

description: For the typographers of Athens, the 19th century closes with their effort of their trade union organization to establish a second Press Agency and to get a part of the product they produce. The following article attempts to understand this effort, the organizational preparations and the realistic conditions for its implementation. Seen through the prism of the monopoly practices applied by the Central Agency, which had developed, during its 25 years of operation, a huge distribution network. In addition, it financed the publication of new editions and was easily synchronized with both politics and the executive authority, making the appearance of new Agencies almost inaccessible. Για τους τυπογράφους της Αθήνας ο 19ος αιώνας κλείνει με την προσπάθεια της συνδικαλιστικής τους οργάνωσης να ιδρύσει ένα δεύτερο πρακτορείο διακίνησης του τύπου και να πάρει μερίδιο του προϊόντος που παράγει. Στο κείμενο που ακολουθεί γίνεται προσπάθεια να κατανοηθεί αυτή η απόπειρα, οι οργανωτικές προπαρασκευές και οι ρεαλιστικές συνθήκες υλοποίησής της. Ειδομένη μέσα από το πρίσμα των μονοπωλιακών πρακτικών που εφάρμοζε το Κεντρικό Πρακτορείο, το οποίο είχε αναπτύξει, κατά την 25ετή λειτουργία του, ένα τεράστιο για τα δεδομένα της εποχής δίκτυο διακίνησης. Επιπλέον, χρηματοδοτούσε την έκδοση νέων εντύπων και συγχρωτιζόταν με ευκολία τόσο με την πολιτική όσο και με την εκτελεστική εξουσία καθιστώντας την είσοδο νέων σχημάτων σχεδόν απροσπέλαστη.
description: δοκιμές, Επιθεώρηση Κοινωνικών Σπουδών // dokimes, Review of Social Studies, No. 25-26 (2022)
The Mirrors Model : Macroscopic Diffusion Without Noise or Chaos
Creators: name: Chiffaudel, Yann
name: Lefevere, Raphaël
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We first clarify through classical examples the status of the laws of macroscopic physics as laws of large numbers. We next consider the mirrors model in a finite $d$-dimensional domain and connected to particles reservoirs at fixed chemical potentials. The dynamics is purely deterministic and non-ergodic. We study the macroscopic current of particles in the stationary regime. We show first that when the size of the system goes to infinity, the behaviour of the stationary current of particles is governed by the proportion of orbits crossing the system. This allows to formulate a necessary and sufficient condition on the distribution of the set of orbits that ensures the validity of Fick's law. Using this approach, we show that Fick's law relating the stationary macroscopic current of particles to the concentration difference holds in three dimensions and above. The negative correlations between crossing orbits play a key role in the argument.
title: Musculoskeletal Manifestations Of Neurofibromatosis Type I
Creators: name: Ip, Siu Kwan Natalie
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Musculoskeletal bone
subject: Musculoskeletal soft tissue
subject: Musculoskeletal spine
subject: MR
subject: CT
subject: Digital radiography
subject: Diagnostic procedure
subject: Education
subject: Genetic defects

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Neurofibromatosis type 1 (NF1) affects multiple organ systems, and musculoskeletal abnormalities are seen in up to 50% of patients. The distinctive feature of NF1 is neurofibromas; we will discuss in detail the different types of neurofibromas and...