cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A significant pure population of the dark European honey bee (Apis mellifera mellifera) remains in Ireland
Creators: name: Hassett, Jack
name: Browne, Keith A
name: McCormack, Grace P
name: Moore, Elizabeth
name: Native Irish Honey Bee Society
name: Soland, Gabrielle
name: Geary, Michael
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: The natural range of the dark European honey bee, Apis mellifera mellifera has been significantly reduced in recent years as a result of importation and replacement of queens with those of other Apis subspecies. Previous studies have indicated that a substantial amount of A. m. mellifera populations throughout Europe are heavily hybridized but that pockets of pure populations do still exist and need to be protected as this subspecies is a highly valuable gene pool and is of considerable conservational interest. Small numbers of Irish bees have been included in previous studies, but scientific information is limited and questions remain about the genetic diversity of bees in Ireland and the extent of introgression into apparent black bees from introduced races and hybrids. The objective of this study was to investigate the genetic composition of the A. m. mellifera population on the island of Ireland with both nuclear (microsatellites) and mitochondrial markers. Molecular data was generated from 412 bees sampled from 24 counties across the island. Mitochondrial data identified 34 different haplotypes, with 63% of bees having sequences identical to three European haplotypes but all other haplotypes being novel. Population structure analysis using microsatellite markers indicates that the Irish population is genetically diverse and that 97.8% of sampled bees were determined to be pure A. m. mellifera. Results from cluster analysis using a Bayesian model approach, and the presence of novel alleles, shows evidence of distinctiveness within the Irish population.
Radiative Shock-Induced Collapse of Intergalactic Clouds
Creators: name: Fragile, P. Chris
name: Murray, Stephen D.
name: Anninos, Peter
name: van Breugel, Wil
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Accumulating observational evidence for a number of radio galaxies suggests an association between their jets and regions of active star formation. The standard picture is that shocks generated by the jet propagate through an inhomogeneous medium and trigger the collapse of overdense clouds, which then become active star-forming regions. In this contribution, we report on recent hydrodynamic simulations of radiative shock-cloud interactions using two different cooling models: an equilibrium cooling-curve model assuming solar metallicities and a non-equilibrium chemistry model appropriate for primordial gas clouds. We consider a range of initial cloud densities and shock speeds in order to quantify the role of cooling in the evolution. Our results indicate that for moderate cloud densities (>1 cm^{-3}) and shock Mach numbers (<20), cooling processes can be highly efficient and result in more than 50% of the initial cloud mass cooling to below 100 K. We also use our results to estimate the final H_2 mass fraction for the simulations that use the non-equilibrium chemistry package. This is an important measurement, since H_2 is the dominant coolant for a primordial gas cloud. We find peak H_2 mass fractions of >0.01 and total H_2 mass fractions of >10^{-5} for the cloud gas. Finally, we compare our results with the observations of jet-induced star formation in ``Minkowski's Object.'' We conclude that its morphology, star formation rate (~ 0.3M_solar/yr) and stellar mass (~ 1.2 x 10^7 M_solar) can be explained by the interaction of a 90,000 km/s jet with an ensemble of moderately dense (~ 10 cm^{-3}), warm (10^4 K) intergalactic clouds in the vicinity of its associated radio galaxy at the center of the galaxy cluster.
description: 30 pages, 7 figures, submitted to Astrophysical Journal
Number Partitioning on a Quantum Computer
Creators: name: De Raedt, H.
name: Michielsen, K.
name: De Raedt, K.
name: Miyashita, S.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present an algorithm to compute the number of solutions of the (constrained) number partitioning problem. A concrete implementation of the algorithm on an Ising-type quantum computer is given.
description: 5 pages, 1 figure, see also http://rugth30.phys.rug.nl/compphys/qce.htm
Detection of Africanized bees in the Dominican Republic
Creators: name: Nikaido, Scott S
name: Villalobos, Ethel M
name: Niyra R Castillo
name: Murillo, Ana Cubero
name: Rodríguez, John M
name: Aracena, Rafael Marte
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: The distribution of the Africanized honey bee (AHB) in the Caribbean region is “patchy”, with some islands, such as Puerto Rico, testing positive for AHB since the mid 1990s, while other regions, including the Dominican Republic and Haiti appeared to be free of AHB. In this study we confirm, through molecular test of mitochondrial genetic material, that AHB is now present in managed colonies in the Dominican Republic. The presence of the Africanized mitotype was established using the cytochrome b/BglII assay. Results show that 39% of the colonies sampled displayed the African haplotype, and 73% apiaries had at least one Africanized colony. Six out of the eight provinces surveyed (excluding Santo Domingo and Dajabón) tested positive for the presence of AHB colonies. The results indicate that AHB is present in the Dominican Republic and that currently it may be more prevalent in the northwest region of the country. However, a more intensive survey is needed to confirm countrywide prevalence of the African genotype, and to examine the situation in neighboring Haiti.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Cart. 185 (11 H 70), f. 0258r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Archives départementales de la Côte-d'Or, Cart. 185 (11 H 70), f. 0258r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Archives départementales de la Côte-d'Or, Cart. 185 (11 H 70), f. 0258r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Variable stars in the Gaia era: Mira, RR Lyrae, delta and Type-II Cepheids
Creators: name: Groenewegen, Martin A. T.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Classical variables like RR Lyrae, classical and Type-II Cepheids and Mira variables all follow period-luminosity relations that make them interesting as distance indicators. Especially the RR Lyrae and delta Cepheids are crucial in establishing the distance scale in the Universe, and all classes of variables can be used as tracers of galactic structure. I will present an overview of recent period-luminosity relations and review the work that has been done using the Gaia DR1 data so far, and discuss possibilities for the future
description: Invited Review at IAU Symposium 330 "Astronomy and Astrophysics in the Gaia sky"
Relativistic MHD with Adaptive Mesh Refinement
Creators: name: Anderson, Matthew
name: Hirschmann, Eric
name: Liebling, Steven L.
name: Neilsen, David
Publisher: name: arXiv
Year: 2006
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: This paper presents a new computer code to solve the general relativistic magnetohydrodynamics (GRMHD) equations using distributed parallel adaptive mesh refinement (AMR). The fluid equations are solved using a finite difference Convex ENO method (CENO) in 3+1 dimensions, and the AMR is Berger-Oliger. Hyperbolic divergence cleaning is used to control the $\nabla\cdot {\bf B}=0$ constraint. We present results from three flat space tests, and examine the accretion of a fluid onto a Schwarzschild black hole, reproducing the Michel solution. The AMR simulations substantially improve performance while reproducing the resolution equivalent unigrid simulation results. Finally, we discuss strong scaling results for parallel unigrid and AMR runs.
description: 24 pages, 14 figures, 3 tables
Additional file 3 of A benchmark of structural variation detection by long reads through a realistic simulated model
Creators: name: Dierckxsens, Nicolas
name: Li, Tong
name: Vermeesch, Joris R.
name: Xie, Zhi
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 3 Review history.
Mormotomyia : Austen 1936
Creators: name: Kirk-Spriggs, Ashley H.
name: Kotrba, Marion
name: Copeland, Robert S.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Mormotomyiidae
Mormotomyia

description: Genus Mormotomyia Austen, 1936
 Mormotomyia: Austen 1936: 426. Type-species: Mormotomyia hirsuta Austen, 1936: 429, by original designation.
description: Published as part of Kirk-Spriggs, Ashley H., Kotrba, Marion & Copeland, Robert S., 2011, Further details of the morphology of the enigmatic African fly Mormotomyia hirsuta Austen (Diptera: Mormotomyiidae), pp. 145 in African Invertebrates 52 (1) on page 149, DOI: 10.5733/afin.052.0107, http://zenodo.org/record/10832931
Absolute frequency measurement of the In$^{+}$ clock transition with a mode-locked laser
Creators: name: von Zanthier, J.
name: Becker, Th.
name: Eichenseer, M.
name: Nevsky, A. Yu.
name: Schwedes, Ch.
name: Peik, E.
name: Walther, H.
name: Holzwarth, R.
name: Reichert, J.
name: Udem, Th.
name: Hänsch, T. W.
name: Pokasov, P. V.
name: Skvortsov, M. N.
name: Bagayev, S. N.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The absolute frequency of the In$^{+}$ $5s^{2 1}S_{0}$ - $5s5p^{3}P_{0}$ clock transition at 237 nm was measured with an accuracy of 1.8 parts in $10^{13}$. Using a phase-coherent frequency chain, we compared the $^{1}S_{0}$ - $^{3}P_{0}$ transition with a methane-stabilized He-Ne laser at 3.39 $μ$m which was calibrated against an atomic cesium fountain clock. A frequency gap of 37 THz at the fourth harmonic of the He-Ne standard was bridged by a frequency comb generated by a mode-locked femtosecond laser. The frequency of the In$^{+}$ clock transition was found to be $1 267 402 452 899.92 (0.23)$ kHz, the accuracy being limited by the uncertainty of the He-Ne laser reference. This represents an improvement in accuracy of more than 2 orders of magnitude on previous measurements of the line and now stands as the most accurate measurement of an optical transition in a single ion.
description: 3 pages, 2 figures. accepted for publication in Opt. Lett
Whitney's Theorem for 2-Regular Planar Digraphs
Creators: name: Archdeacon, Dan
name: DeVos, Matt
name: Hannie, Stefan
name: Mohar, Bojan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C10

description: A digraph is 2-regular if every vertex has both indegree and outdegree two. We define an embedding of a 2-regular digraph to be a 2-cell embedding of the underlying graph in a closed surface with the added property that for every vertex~$v$, the two edges directed away from $v$ are not consecutive in the local rotation around $v$. In other words, at each vertex the incident edges are oriented in-out-in-out. The goal of this article is to provide an analogue of Whitney's theorem on planar embeddings in the setting of 2-regular digraphs. In the course of doing so, we note that Tutte's Theorem on peripheral cycles also has a natural analogue in this setting.
description: 8 pages
Thermoelectric power factor limit of a 1D nanowire
Creators: name: Chen, I-Ju
name: Burke, Adam
name: Svilans, Artis
name: Linke, Heiner
name: Thelander, Claes
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In the past decade, there has been significant interest in the potentially advantageous thermoelectric properties of one-dimensional (1D) nanowires, but it has been challenging to find high thermoelectric power factors based on 1D effect in practice. Here we point out that there is an upper limit to the thermoelectric power factor of non-ballistic 1D nanowires, as a consequence of the recently established quantum bound of thermoelectric power output. We experimentally test this limit in quasi-ballistic InAs nanowires by extracting the maximum power factor of the first 1D subband through I-V characterization, finding that the measured maximum power factors conform to the theoretical limit. The established limit predicts that a competitive power factor, on the order of mW/m-K^2, can be achieved by a single 1D electronic channel in state-of-the-art semiconductor nanowires with small cross-section and high crystal quality.
UHPLC-ESI-ORBITRAP-MS analysis of the native Mapuche medicinal plant palo negro (Leptocarpha rivularis DC. – Asteraceae) and evaluation of its antioxidant and cholinesterase inhibitory properties
Creators: name: Jiménez-González, Andrea
name: Quispe, Cristina
name: Bórquez, Jorge
name: Sepúlveda, Beatriz
name: Riveros, Felipe
name: Areche, Carlos
name: Nagles, Edgar
name: Olimpo García-Beltrán
name: Simirgiotis, Mario J.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: UHPLC/ESI/MS identification of organic compounds is the first step in the majority of screening techniques for the characterization of biologically active metabolites in natural sources. This paper describes a method for the fast identification and characterisation of secondary metabolites in Leptocarpha rivularis DC. (Palo negro) extracts by HPLC/UV (DAD)–Mass Spectrometry (HPLC/MS). The plant is used for the treatment of several diseases since pre-hispanic Mapuche times. Thirty-seven compounds were detected in the aqueous edible extract for the first time including 4 sesquiterpenes, 10 flavonoids, 9 oxylipins, 2 organic acids, and 11 phenolic acids. In addition, phenolic content antioxidant and cholinesterase inhibitory activities were measured for the first time using the edible infusion. The total polyphenol content of the infusion was 230.76 ± 2.5 mmol GAE/kg dry weight, while the antioxidant activity was 176.51 ± 28.84; 195.28 ± 4.83; and 223.92 ± 2.95 mmol TE/kg dry weight, for the DPPH, ABTS, and FRAP assays, respectively. The cholinesterase inhibitory activity was 7.38 ± 0.03 and 5.74 ± 0.06 mmol GALAE/kg, for the inhibition of acetylcholinesterase AChE and BChE, respectively, showing that this plant is a candidate for the isolation of compounds that can be useful for the treatment of neurodegenerative diseases. Furthermore, this plant could serve also as a raw material for the production of dietary supplements, due to its content of polyphenolic compounds.
Writing and storing information in an array of magnetic vortex nanodisks using their azimuthal modes
Creators: name: Vigo-Cotrina, H.
name: Guimarães, A. P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The switching of a vortex core of a single disk in an array of a multilayer system is investigated by micromagnetic simulation. We found that the perpendicular uniaxial anisotropy (PUA) decreases the frequencies of the azimuthal mode in disks with magnetic vortex configuration. We obtained a phase diagram of magnetic field intensity vs. frequency of the azimuthal mode, as a function of the value of perpendicular uniaxial anisotropy. We demonstrated that rotating magnetic fields (CW and CCW) with frequency equal to azimuthal modes can be used to switch the vortex core of single disks in a disk array. This allows obtaining different memory states with a single array of nanodisks, and therefore writing information through the application of rotating fields.
Short-Period Variable Stars in the M31 Halo
Creators: name: Dolphin, A. E.
name: Saha, A.
name: Olszewski, E. W.
name: Thim, F.
name: Skillman, E. D.
name: Gallagher, J. S.
name: Hoessel, J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the findings of a new search for RR Lyraes in an M31 halo field located 40 arcminutes from the nucleus of the galaxy along the minor axis. We detected 37 variable stars, of which 24 are classified as RR Lyraes and the others are ambiguous. Estimating a completeness fraction of ~24%, we calculate that there are approximately 100 RR Lyraes in the field, which is consistent with what is expected from deep HST color-magnitude diagrams. We calculate a mean magnitude of g=25.15+/ 0.03, which we interpret to mean that the mean metallicity of RR Lyraes is significantly lower than that of the M31 halo as a whole. The presence of ancient, metal-poor stars opens the possibility that, initially, the M31 halo appeared much like the Milky Way halo.
description: 43 pages, 9 figures. Accepted for publication in AJ
Embedding the Reissner-Nordstrom spacetime in Euclidean and Minkowski spaces
Creators: name: Jacob, Uri
name: Piran, Tsvi
Publisher: name: arXiv
Year: 2006
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We examine embedding diagrams of hypersurfaces in the Reissner-Nordstrom black hole spacetime. These embedding diagrams serve as useful tools to visualize the geometry of the hypersurfaces and of the whole spacetime in general.
description: 13 pages, 10 figures
Additional file 1 of Machine learning assisted Cameriere method for dental age estimation
Creators: name: Shen, Shihui
name: Liu, Zihao
name: Wang, Jian
name: Fan, Linfeng
name: Ji, Fang
name: Tao, Jiang
Publisher: name: figshare
Year: 2021
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1: Table S1. List of the tuned hyperparameters for each Machine Learning algorithm.
Identification of Overlapping Communities via Constrained Egonet Tensor Decomposition
Creators: name: Sheikholeslami, Fatemeh
name: Giannakis, Georgios B.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: Detection of overlapping communities in real-world networks is a generally challenging task. Upon recognizing that a network is in fact the union of its egonets, a novel network representation using multi-way data structures is advocated in this contribution. The introduced sparse tensor-based representation exhibits richer structure compared to its matrix counterpart, and thus enables a more robust approach to community detection. To leverage this structure, a constrained tensor approximation framework is introduced using PARAFAC decomposition. The arising constrained trilinear optimization is handled via alternating minimization, where intermediate subproblems are solved using the alternating direction method of multipliers (ADMM) to ensure convergence. The factors obtained provide soft community memberships, which can further be exploited for crisp, and possibly-overlapping community assignments. The framework is further broadened to include time-varying graphs, where the edgeset as well as the underlying communities evolve through time. Performance of the proposed approach is assessed via tests on benchmark synthetic graphs as well as real-world networks. As corroborated by numerical tests, the proposed tensor-based representation captures multi-hop nodal connections, that is, connectivity patterns within single-hop neighbors, whose exploitation yields a more robust community identification in the presence of mixing as well as overlapping communities.
Gamma-Ray Bursts: Jets and Energetics
Creators: name: Frail, D. A.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The relativistic outflows from gamma-ray bursts are now thought to be narrowly collimated into jets. After correcting for this jet geometry there is a remarkable constancy of both the energy radiated by the burst and the kinetic energy carried by the outflow. Gamma-ray bursts are still the most luminous explosions in the Universe, but they release energies that are comparable to supernovae. The diversity of cosmic explosions appears to be governed by the fraction of energy that is coupled to ultra-relativistic ejecta.
description: Paper presented at "The Restless High-Energy Universe", May 5-8 2003 Royal Tropical Institute, Amsterdam
Gravity Theories with Background Fields and Spacetime Symmetry Breaking
Creators: name: Bluhm, Robert
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: An overview is given of effective gravitational field theories with fixed background fields that break spacetime symmetry. The behavior of the background fields and the types of excitations that can occur depend on whether the symmetry breaking is explicit or spontaneous. For example, when the breaking is spontaneous, the background field is dynamical and massless Nambu--Goldstone and massive Higgs excitations can appear. However, if the breaking is explicit, the background is nondynamical, and in this case additional metric or vierbein excitations occur due to the loss of local symmetry, or these excitations can be replaced by dynamical scalar fields using a Stuckelberg approach. The interpretation of Noether identities that must hold in each case differs, depending on the type of symmetry breaking, and this affects the nature of the consistency conditions that must hold. The Noether identities also shed light on why the Stuckelberg approach works, and how it is able to restore the broken spacetime symmetry in a theory with explicit breaking.
Design, synthesis and biological evaluation of 4-bromo-N-(3,5-dimethoxyphenyl)benzamide derivatives as novel FGFR1 inhibitors for treatment of non-small cell lung cancer
Creators: name: Zixin Xie
name: Donghua Cheng
name: Luo, Lu
name: Guoliang Shen
name: Suwei Pan
name: Yaqian Pan
name: Chen, Bo
name: Xuebao Wang
name: Zhiguo Liu
name: Zhang, Yuan
name: Faqing Ye
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: A series of 4-bromo-N-(3,5-dimethoxyphenyl)benzamide derivatives were designed and synthesised as novel fibroblast growth factor receptor-1 (FGFR1) inhibitors. We found that one of the most promising compounds, C9, inhibited five non-small cell lung cancer (NSCLC) cell lines with FGFR1 amplification, including NCI-H520, NCI-H1581, NCI-H226, NCI-H460 and NCI-H1703. Moreover, the IC50 values for the compound C9 were 1.36 ± 0.27 µM, 1.25 ± 0. 23 µM, 2.31 ± 0.41 µM, 2.14 ± 0.36 µM and 1.85 ± 0.32 µM, respectively. The compound C9 arrested the cell cycle at the G2 phase in NSCLC cell lines. The compound C9 also induced cellular apoptosis and inhibited the phosphorylation of FGFR1, PLCγ1 and ERK in a dose-dependent manner. In addition, molecular docking experiments showed that compound C9 binds to FGFR1 to form six hydrogen bonds. Taken together, our data suggested that the compound C9 represented a promising lead compound-targeting FGFR1.
Structure of a hot accretion flow in the presence of outflow and convection with large ordered magnetic field
Creators: name: Ghasemnezhad, Maryam
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Hydrodynamics and magnetohydrodynamic simulations of hot accretion flow have indicated that there is an inward decreasing of mass accretion rate with decreasing radius. Consequently, we have a flatter density profile ($ρ\propto r^{-p}$ with $p\propto 1.5-s$ in the case of $\dot{M}\propto r^{s}$, $0 \leq s<1$) compared to the case of a constant accretion rate (($ρ\propto r^{-\frac{3}{2}}$). In order to describe this behavior two models have been proposed: inflow-outflow solution and convection-dominated accretion flows. We have studied the properties of a hot accretion flow in the presence of convection, large scale magnetic field and outflow. We consider an axisymmetric viscous flow in the steady state. We used the self-similar solutions to solve the 1.5 dimensional inflow-outflow equations. We have assumed that the convection as a free parameter in our model for simplicity. We have considered two components of magnetic field (toroidal and vertical) in this paper. We have shown that the strong convection makes the inflow accretes and rotates slower while it becomes hotter and thicker. We have found that the thickness of the disc deviates from non-convective solutions obviously. We have represented that two components of magnetic field have the opposite effects on the thickness of the disc and similar effects on the radial and angular velocities of the flow.
description: 7 pages, 4 Figures, Accepted for publication in MNRAS. arXiv admin note: text overlap with arXiv:1705.08356
Design, synthesis and biological evaluation of 4-bromo-N-(3,5-dimethoxyphenyl)benzamide derivatives as novel FGFR1 inhibitors for treatment of non-small cell lung cancer
Creators: name: Zixin Xie
name: Donghua Cheng
name: Luo, Lu
name: Guoliang Shen
name: Suwei Pan
name: Yaqian Pan
name: Chen, Bo
name: Xuebao Wang
name: Zhiguo Liu
name: Zhang, Yuan
name: Faqing Ye
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: A series of 4-bromo-N-(3,5-dimethoxyphenyl)benzamide derivatives were designed and synthesised as novel fibroblast growth factor receptor-1 (FGFR1) inhibitors. We found that one of the most promising compounds, C9, inhibited five non-small cell lung cancer (NSCLC) cell lines with FGFR1 amplification, including NCI-H520, NCI-H1581, NCI-H226, NCI-H460 and NCI-H1703. Moreover, the IC50 values for the compound C9 were 1.36 ± 0.27 µM, 1.25 ± 0. 23 µM, 2.31 ± 0.41 µM, 2.14 ± 0.36 µM and 1.85 ± 0.32 µM, respectively. The compound C9 arrested the cell cycle at the G2 phase in NSCLC cell lines. The compound C9 also induced cellular apoptosis and inhibited the phosphorylation of FGFR1, PLCγ1 and ERK in a dose-dependent manner. In addition, molecular docking experiments showed that compound C9 binds to FGFR1 to form six hydrogen bonds. Taken together, our data suggested that the compound C9 represented a promising lead compound-targeting FGFR1.
Temporal Simultons in Optical Parametric Oscillators
Creators: name: Jankowski, Marc
name: Marandi, Alireza
name: Phillips, C. R.
name: Hamerly, Ryan
name: Ingold, K. A.
name: Byer, R. L.
name: Fejer, M. M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We identify and demonstrate a regime of operation in optical parametric oscillators (OPOs) in which the formation of temporal simultons produces stable half-harmonic pulses. Simultons are simultanous bright-dark solitons of a signal field at frequency $ω$ and the pump field at $2ω$ which form in a quadratic nonlinear medium. The formation of simultons in an OPO is evidenced by sech$^2$ spectra with broad instantaneous bandwidths which increase with pump power, and large slope efficiencies. In contrast to conventional synchronously pumped OPOs, operation in this regime is achieved by using relatively large parametric gains, and a low finesse resonator detuned to a slightly longer roundtrip time than the pump repetition period. In the experiment we achieve sub-50 fs sech$^2$ pulses with a slope efficiency of 570%, and a conversion efficiency of 55% as a result of formation of simultons in an OPO. We verify the distinct features of OPO operation in the simulton regime analytically and numerically. These results represent a fundamental shift in the understanding and design of OPOs, in which the nonlinear dynamics that arise during asynchronous operation can be used to efficiently generate few-cycle long-wavelength frequency combs.
description: 5 Pages, 3 Figures
Detecting Axion Stars with Radio Telescopes
Creators: name: Bai, Yang
name: Hamada, Yuta
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: When axion stars fly through an astrophysical magnetic background, the axion-to-photon conversion may generate a large electromagnetic radiation power. After including the interference effects of the spacially-extended axion-star source and the macroscopic medium effects, we estimate the radiation power when an axion star meets a neutron star. For a dense axion star with $10^{-13}\,M_\odot$, the radiated power is at the order of $10^{11}\,\mbox{W}\times(100\,μ\mbox{eV}/m_a)^4\,(B/10^{10}\,\mbox{Gauss})^2$ with $m_a$ as the axion particle mass and $B$ the strength of the neutron star magnetic field. For axion stars occupy a large fraction of dark matter energy density, this encounter event with a transient $\mathcal{O}(0.1\,\mbox{s})$ radio signal may happen in our galaxy with the averaged source distance of one kiloparsec. The predicted spectral flux density is at the order of $μ$Jy for a neutron star with $B\sim 10^{13}$ Gauss. The existing Arecibo, GBT, JVLA and FAST and the ongoing SKA radio telescopes have excellent discovery potential of dense axion stars.
description: 16 pages, 2 figures
A thiophenic alkynylplatinum(II) terpyridyl complex: synthesis and photophysical properties
Creators: name: Xu, Peng
name: Qin, Xi
name: Duan, Huiyuan
name: Chen, Huafeng
name: Zhai, Lei
name: Qin, Yanjie
name: Liu, Xin
name: Zuo, Yulan
name: Pei, Shuchen
name: Lian, Xin
name: Yi, Huan
name: Su, Xiaodong
name: Zhang, Jinling
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biophysics
Biochemistry
Space Science
Physical Sciences not elsewhere classified
Medicine
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Cancer

description: A new thiophenic alkynylplatinum(II) terpyridyl complex [tBuArC≡CPt(tpy)]PF6 (tpy = 2,2′:6′,2″-terpyridine; Ar = [(MeC4H2S)(C≡C)]2C6H2) has been synthesized in five steps in 45% total yield. The photophysical properties were studied by steady-state spectroscopy and transient spectroscopy and obvious metal-metal interactions and π-π stacking were found in a series of solvents. Concentration dependent emission data show that the complex exhibited aggregation-induced fluorescence enhancement at low concentrations while aggregation-induced fluorescence quenching at high concentrations. The complex displayed biexponential decays with lifetimes in the range of nanoseconds in dilute dichloromethane and acetonitrile solutions.
Affine Histories in Quantum Gravity: Introduction and the Representation for a Cosmological Model
Creators: name: Kessari, Smaragda
Publisher: name: arXiv
Year: 2006
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: It is shown how consistent histories quantum cosmology can be realised through Isham's Histories Projection Operator consistent histories scheme. This is done by using an affine algebra instead of a canonical one and also by using cocycle representations. A regularisation scheme allows us to find a history Hamiltonian which exists as a proper self-adjoint operator. The role of a cocycle choice is also discussed.
description: 31 pages, LaTeX, no figures
INVESTIGATION OF PUEA IN COGNITIVE RADIO NETWORKS USING ENERGY DETECTION IN DIFFERENT CHANNEL MODEL
Creators: name: 1Walid. R. Ghanem
name: Shokair, Mona
name: MI Dessouky
Publisher: name: figshare
Year: 2018
Subjects: subject: 90699 Electrical and Electronic Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: ABSTRACT
Primary User Emulation Attack (PUEA) is one of the major threats to the spectrum sensing in cognitive radio networks. This paper studies the PUEA using energy detection that is based on the energy of the received signal. It discusses the impact of increasing the number of attackers on the performance of secondary user. Moreover, studying how the malicious user can emulate the Primary User (PU) signal is made. This is the first analytical method to study PUEA under a different number of attackers. The detection of the PUEA increases with increasing the number of attackers and decreases when changing the channel from lognormal to Rayleigh fading.
KEYWORDS:
Cognitive Radio, Primary User Emulation Attacks (PUEA), energy detector.
Probable intermediate mass black holes in NGC4559: XMM-Newton spectral and timing constraints
Creators: name: Cropper, Mark
name: Soria, Roberto
name: Mushotzky, Richard F.
name: Wu, Kinwah
name: Markwardt, Craig B.
name: Pakull, Manfred
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have examined X-ray and optical observations of two ultra-luminous X-ray sources, X7 and X10 in NGC4559, using XMM-Newton, Chandra and HST. The UV/X-ray luminosity of X7 exceeds 2.1e40 erg/s in the XMM-Newton observation, and that of X10 is >1.3e40 erg/s. X7 has both thermal and power-law spectral components. The characteristic temperature of the thermal component is 0.12 keV. The power-law components in the two sources both have slopes with photon index \~2.1. A timing analysis of X7 indicates a break frequency at 28 mHz in the power spectrum, while that for X10 is consistent with an unbroken power law. The luminosity of the blackbody component in the X-ray spectrum of X7 and the nature of its time variability provides evidence that this object is an intermediate mass black hole accreting at sub-Eddington rates, but other scenarios which require high advection efficiencies from a hollowed-out disk might be possible. The emission from X10 can be characterised by a single power-law. This source can be interpreted either as an intermediate mass black hole, or as a stellar-mass black hole with relativistically-beamed Comptonised emission. There are four optical counterparts in the error circle of X7. No counterparts are evident in the error circle for X10.
description: accepted for publication in MNRAS
Times Ranking versus ResearchGate’s Indicators: An Analysis of Presence and Activities of Political Sciences Field
Creators: name: Tavosi, Maryam
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 460508
subject: Information retrieval and web search
classificationCode: 390107
subject: Humanities and social sciences curriculum and pedagogy (excl. economics, business and management)

description: Purpose: This study analyzes the activities of top Times researchers in the field of political science with an emphasis on examining the ResearchGate network.

Method: This study opted for altmetric approach. Two research communities have been surveyed. The number of 145 faculty members affiliated to the top 10 universities of the Times 2021 in the field of political science was stratified sampling randomly, selected. Participation in the ResearchGate network was examined, for them. For the attendees, the indicators of citations, RG-score, and reads were extracted and compared. For the top 15 best Times scientific institutes, the RG scores per member and publication per member were calculated and compared. Correlation between Times Ranking and ResearchGate's indicators, done too. For data analysis, LibreOfficeCalc, and SPSS22 were exploited.

Findings: Only, 39% of all faculty members belong to the best Times centers in the field of political science, have seen by registration in the ResearchGate network. For 57 registered individuals, there was a significant correlation between ResearchGate's indicators with each other. But there was no significant relationship between the Times rankings and the mentioned indicators, except for the reads (P-value = 0.018) with a weak reverse correlation (Spearman coefficient= - 0.314). Furthermore, comparative analysis for the top 15 Times institutes had done from standpoint of RG-Score, too.

Originality: The Correlation relationship between Times rank and ResearchGate’s indicators in the field of political science, in addition, the participation of faculty members of the best scientific centers in this mentioned field had not been done yet.
$k$-Foldability of Words
Creators: name: Bjorkman, Beth
name: Cochran, Garner
name: Gao, Wei
name: Keough, Lauren
name: Kirsch, Rachel
name: Phillipson, Mitch
name: Rorabaugh, Danny
name: Smith, Heather
name: Wise, Jennifer
Publisher: name: arXiv
Year: 2017
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05A15 (Primary) 05C05, 20M05 (Secondary)

description: We extend results regarding a combinatorial model introduced by Black, Drellich, and Tymoczko (2017+) which generalizes the folding of the RNA molecule in biology. Consider a word on alphabet $\{A_1, \overline{A}_1, \ldots, A_m, \overline{A}_m\}$ in which $\overline{A}_i$ is called the complement of $A_i$. A word $w$ is foldable if can be wrapped around a rooted plane tree $T$, starting at the root and working counterclockwise such that one letter labels each half edge and the two letters labeling the same edge are complements. The tree $T$ is called $w$-valid. We define a bijection between edge-colored plane trees and words folded onto trees. This bijection is used to characterize and enumerate words for which there is only one valid tree. We follow up with a characterization of words for which there exist exactly two valid trees. In addition, we examine the set $\mathcal{R}(n,m)$ consisting of all integers $k$ for which there exists a word of length $2n$ with exactly $k$ valid trees. Black, Drellich, and Tymoczko showed that for the $n$th Catalan number $C_n$, $\{C_n,C_{n-1}\}\subset \mathcal{R}(n,1)$ but $k\not\in\mathcal{R}(n,1)$ for $C_{n-1}
A Higher Dimensional Stationary Rotating Black Hole Must be Axisymmetric
Creators: name: Hollands, Stefan
name: Ishibashi, Akihiro
name: Wald, Robert M.
Publisher: name: arXiv
Year: 2006
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A key result in the proof of black hole uniqueness in 4-dimensions is that a stationary black hole that is ``rotating''--i.e., is such that the stationary Killing field is not everywhere normal to the horizon--must be axisymmetric. The proof of this result in 4-dimensions relies on the fact that the orbits of the stationary Killing field on the horizon have the property that they must return to the same null geodesic generator of the horizon after a certain period, $P$. This latter property follows, in turn, from the fact that the cross-sections of the horizon are two-dimensional spheres. However, in spacetimes of dimension greater than 4, it is no longer true that the orbits of the stationary Killing field on the horizon must return to the same null geodesic generator. In this paper, we prove that, nevertheless, a higher dimensional stationary black hole that is rotating must be axisymmetric. No assumptions are made concerning the topology of the horizon cross-sections other than that they are compact. However, we assume that the horizon is non-degenerate and, as in the 4-dimensional proof, that the spacetime is analytic.
description: 24 pages, no figures, v2: footnotes and references added, v3: numerous minor revisions
Low-Luminosity AGNs at the Highest Resolution: Jets or Accretion Flows?
Creators: name: Anderson, James M.
name: Ulvestad, James S.
name: Ho, Luis C.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Six low-luminosity active galactic nuclei have been imaged at multiple frequencies from 1.7--43 GHz (2.3--15 GHz for three of the galaxies) using the Very Long Baseline Array. In spite of dynamic ranges of about 100 in several frequency bands, all six galaxies remain unresolved, with size limits at 8.4 GHz of 10^3--10^4 times the Schwarzschild radii of the black holes inferred at their galactic centers. The galaxy spectra are roughly flat from 1.7 to 43 GHz, rather than steepening to classical optically thin synchrotron spectra at high frequencies. Although the spectral slopes somewhat resemble predictions for advection-dominated accretion flows, the luminosities are too high for the black hole masses of the galaxies and the slight spectral steepening at high frequencies cannot be explained by standard simple models of such accretion flows. In contrast, compact jets can accommodate the average spectral index, the relatively high radio luminosity, and the unresolved appearance, but only if the jets in all six galaxies are fairly close to our line of sight. This constraint is in agreement with inclination angle predictions for five of the six AGNs based on the dusty torus unification model.
description: 28 pages, 7 figures, accepted for publication in the Astrophysical Journal
Macroscopic Local Realism Incompatible with Quantum Mechanics: Failure of Local Realism where Measurements give Macroscopic Uncertainties
Creators: name: Reid, M. D.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We show that quantum mechanics predicts a contradiction with local hidden variable theories for photon number measurements which have limited resolving power, to the point of imposing an uncertainty in the photon number result which is macroscopic in absolute terms. We show how this can be interpreted as a failure of a new premise, macroscopic local realism.
description: 9 pages 3 figures
Additional file 10 of P-tau and neurodegeneration mediate the effect of β-amyloid on cognition in non-demented elders
Creators: name: Ma, Ling-Zhi
name: Hu, Hao
name: Wang, Zuo-Teng
name: Ou, Ya-Nan
name: Dong, Qiang
name: Tan, Lan
name: Yu, Jin-Tai
Publisher: name: figshare
Year: 2021
Subjects: Biochemistry
Cell Biology
Neuroscience
Mental Health

description: Additional file 10. Mediation analyses of Aβ and cognitive measurements with biomarkers as mediators in A-MCI participants.
Biobeam - Rigorous wave-optical simulations of light-sheet microscopy
Creators: name: Weigert, Martin
name: Myers, Eugene W.
name: Kreysing, Moritz
Publisher: name: arXiv
Year: 2017
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Sample-induced image-degradation remains an intricate wave-optical problem in light-sheet microscopy. Here we present biobeam, an open-source software package that enables to simulate operational light-sheet microscopes by combining data from 10^5 - 10^6 multiplexed and GPU-accelerated point-spread-function calculations. The wave-optical nature of these simulations leads to the faithful reproduction of spatially varying aberrations, diffraction artifacts, geometric image distortions, adaptive optics, and emergent wave optical phenomena, and renders image-formation in light-sheet microscopy computationally tractable.
description: changed video codec to h264, no other changes
SING 2017 whole of Program analysis.pdf
Creators: name: McDonald, Gregory
Publisher: name: figshare
Year: 2018
Subjects: subject: Environmental Science
subject: 60204 Freshwater Ecology
subject: FOS: Biological sciences

description: This paper is an extract from 'Streamwatch Indications for New Guidelines report, SING 2017'. It provides a summary of results for the aggregation of data from all sites across the Greater Sydney region, within the SING 2017 analysis. The variability of environmental factors and degrees of disturbance across sites will necessarily result in the broadest but arguably still useful, range of values from this report. Sites used in this analysis dominate the lowland (<150m), with only six sites considered upland. Conductivity values from those sites were not aggregated with the lowland set. Review of the Original SING 2017 report will provide context, intent and methods informing this extract.