cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identification of novel small molecule inhibitors of Aurora B kinase
Creators: name: Brescia, Annalisa
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2015

description: Aurora kinases (A, B and C) are frequently amplified and overexpressed in a wide variety of cancers, and their up-regulation often correlates with poor prognosis. The potential role of these kinases in tumorigenesis indicates that  they could be appealing target for molecular therapy. Although extensive efforts have been done to develop Aurora kinases inhibitors (AKIs), selective for A, B or both kinases, so far, none of them have yet been approved by FDA due to their severe toxicity. The aim of this study has been to identify novel and powerful AKIs, Aurora B kinase inhibitors.
In living cells, we tested the inhibition of Aurora B kinase by 7 potential novel AKIs, called MK1-7, which share a common molecular scaffold, by evaluating Serine 10 phosphorylation of Histone H3, a bona fide downstream  target of the kinase in HeLa cells. We selected 4 compounds (MK1, 2, 6 and 7), that were able to reduce phosphorylation of Histone H3 at 10 nM dose. Then, we evaluated the effect of each inhibitor on: cell cycle progression, spindle assembly checkpoint (SAC) escape, cell proliferation and viability. Although with different efficacy, these 4 MKs perturb cell cycle progression inducing polyploidy. In addition, cells treated with the 4 MKs escape from mitosis overtaking the SAC checkpoint. These MKs blocked cell growth with an IC50 ranging from 0.37 to 2.27 nM (MK1 IC50=1,2 nM; MK2 IC50=2,27 nM; MK6 IC50=0,44 nM; MK7 IC50=0,37 nM). Based on MK7 most powerful efficacy, its effect on cell division and viability was more extensively investigated. HeLa cells treated with MK7 were positive for apoptotic Annexin V and propidium iodide staining and showed an increase in caspase 3 and PARP cleavages, indicating induction of apoptosis. Additionally, MK7 treatment caused alteration in mitotic spindle formation, chromosome segregation and cytokinesis. Finally, we observed that MK7 is able to inhibit growth of A2780 (human ovarian carcinoma), HL-60 (human promyelocytic leukemia), HCT116 (human colorectal carcinoma) and 8505-C (human undifferentiated thyroid carcinoma) cell lines. In conclusion, our in vitro data have identified in MK7 a powerful compound which could be widely used to inhibit Aurora B kinase in different cancer types.
Charge and spin transport over record distances in GaAs metallic n-type nanowires : II nonlinear charge transport
Creators: name: Hijazi, Hadi
name: Paget, Daniel
name: Monier, Guillaume
name: Grégoire, Gabin
name: Leymarie, Joël
name: Gil, Evelyne
name: Cadiz, Fabian
name: Robert-Goumet, Christine
name: André, Yamina
Publisher: name: arXiv
Year: 2020
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We have investigated the photocarrier charge transport in n-type metallic GaAs nanowires (~ 10^17 cm^-3 doping level), grown by hydride vapor phase epitaxy (HVPE) on Si(111) substrates. Analysis of the luminescence intensity spatial profiles for selected energies in the spectrum allows us to determine the spatial distribution of photoelectrons, minority photoholes and electrons of the Fermi sea as a function of distance from the light excitation spot. This analysis shows that charge can be transported over record distances larger than 25 (micro)m at 6K, in spite of the expected localization of minority holes in the potential fluctuations generated by statistical fluctuations of the donor concentration. It is shown that transport is little affected by the fluctuations because of the build up of large internal electric fields which strongly increase the hole and electron mobilities and therefore enable transport. Comparison of the spatial profiles of the emissions due to hot electrons and to the Fermi sea gives evidence for at least three spatial zones, including a zone of excess intrinsic electrons near the excitation spot and a zone of depletion of these electrons at a distance larger than 2-10 (micro)m depending on excitation power. The internal outward electric field increases the kinetic energy of photoholes in the fluctuations so that after a given distance to the excitation spot, there occurs ballistic transport over the fluctuations.
3D finite volume simulations of dense granular flow inside rotating cylinders
Creators: name: De Monaco, Gaetano
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2015

description: Granular materials are widely diffused in industry as well as in nature, but a reliable and effective description of their motion is still at a rather early stage of development. Among the benchmark problems of granular dense flow, the rotating drum is one of the most challenging, yet intriguing and technologically relevant. In proper ranges of operating conditions, granular materials inside rotating drums display a continuum motion near their free surface. The motion of those discrete systems has been studied both experimentally and through Discrete Element Method (DEM) numerical simulations; however, it can also be regarded as the flow of a continuum medium, thus allowing a continuum mechanics approach.

In this thesis, we solve the continuum dynamic equations by adopting the visco-plastic JFP constitutive model (Jop et al., Nature 441, 727-730, 2006) for the stress tensor, and study the continuous flow of dry grains inside axially rotating cylinders through 3D Finite Volume simulations (FVM). We investigate the effect of the ratio D/dp between the diameters of cylinder and particles, of the aspect ratio of the cylinder AR=width/diameter, of the angular velocity omega, and of the slip between drum wall and particles.

Numerical results are found to quantitatively agree with experimental results from different authors, and also catches some distinctive features of the drum flow of granular materials, such as, e.g., the existence of axial components of the surface velocity, or the differences of the flow fields near the lateral wall and at the center plane, ect.

Our simulations demonstrate that the basic physics of the dense granular flow is captured by the simple JFP model, and that continuum mechanics can be used to get a physical insight in granular dense state phenomenology. CFD simulations may then be of help to rationalize the broad wealth of experimental results with these materials.
title: A rare presentation of a canal of Nuck hernia containing uterus, ovary and both fallopian tubes
Creators: name: Van Den Berge, Steven
Publisher: name: EURORAD
Year: 2020
Subjects: subject: Paediatric radiology
subject: Genital / Reproductive system female
subject: Peritoneum
subject: Ultrasound
subject: Genital / Reproductive system female
subject: Clinical Cases

description: Clinical History: A one-month-old female infant presented to the emergency department with a palpable, painful mass in her right labia.  Her parents noticed she was uncomfortable,  wept easily and had a decrease in appetite.  On physical examination, the infant was alert, had no fever and showed normal cardiopulmonary auscultation as well as intestinal peristaltis. The labial mass could only partially be reduced manually.

description: 1 month, female
Methodisches Vorgehen in der benutzerorientierten Produktentwicklung - Entwicklung von Produkten und Umgebungen für Menschen mit Kompetenzeinschränkungen
Creators: name: Geißler, Linda
Publisher: name: aw&I Conference
Year: 2018

description: Im USEability LAB am IHD werden Forschungsthemen mit unterschiedlichen Fragestellungen aus dem Bereich der Produktentwicklung und der Gestaltung von (Wohn-) Räumen für Senioren und Menschen mit Kompetenzeinschränkungen. Bei der Ermittlung der Anforderungen an die zu gestaltenden Produkte und Umgebungen steht der Benutzer mit seinen individuellen Eigenschaften jederzeit im Fokus. In der Produktentwicklung, insbesondere der Softwareentwicklung, gibt es bereits eine Vielzahl von Methoden zur Analyse der Benutzeranforderungen und zur Überprüfung der Produktlösungen aus der Benutzersicht. Doch für die Arbeit, in der ein komplexes System aus Benutzer(n), Objekten und der räumlichen Umgebung betrachtet werden muss, eignen sich bisherige Methoden nur im Ansatz. Begleitend in verschiedenen Forschungsprojekten wurde ein eigenes methodisches Vorgehen zur Anforderungsanalyse entwickelt, wobei verschiedene bestehende Methoden kombiniert und erweitert wurden. Die DIN EN ISO 9241-210 bietet eine Grundlage, die sich als sehr geeignet für die Übertragung auf die in Projekten des USEability LABs auftretende Fragestellungen erwiesen hat. In der benutzerorientierten Produktentwicklung steht der Mensch mit seinen Eigenschaften, Fähigkeiten, Zielen und Bedürfnissen bezüglich eines zu entwickelnden Produktes oder einer Umgebung im Vordergrund. Ein Schwerpunkt der Arbeit im USEability LAB am IHD sind Produkte und Umgebungen für Menschen mit Kompetenzeinschränkungen. Menschen, die mit einer sensorischen, motorischen und/oder kognitiven Einschränkung leben, haben besondere Anforderungen an ihre Umwelt. Sie verfügen oftmals aufgrund ihres Handicaps über eine verminderte Anpassungsleistung und sind daher stärker darauf angewiesen, dass sich ihre Umgebung an sie anpasst. Zudem sind die Art und die Ausprägung der Einschränkungen sehr verschieden, was dazu führt, dass es ein pauschales „barrierefrei“ oder „behindertengerecht“ nicht geben kann.


In diesem Beitrag wird das methodische Vorgehen vorgestellt, das es ermöglicht, einen Perspektivwechsel zu vollziehen und die Anforderungen an ein zu entwickelndes Produkt oder eine zu gestaltende Umgebung aus Sicht der Benutzer zu ermitteln.
description: aw&I Conference, Bd. 3 (2018): innteract2018
Additional file 1 of Women’s experiences of surviving severe obstetric complications: a qualitative inquiry in southern Ghana
Creators: name: Amegavluie, Ruby Elikem Afi
name: Ani-Amponsah, Mary
name: Naab, Florence
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Appendix A.
A study of immune-tolerance control in the pathogenesis of Haematological disorders and Chronic-infection.
Creators: name: Rubino, Valentina
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2015

description: The main topic of this thesis was to evaluate the relevance of immune-tolerance dys-regulation in the pathogenesis of some haematopoietic disorders and for the occurrence of immune pathological complications in chronic infection models.
In Paroxysmal Nocturnal Haemoglobinuria model, we described the  occurrence of Treg reduction and NKTi increase in untreated PNH patients as well as the ability of the Complement blocking monoclonal antibody  culizumab to selectively restore B and NKTi peripheral concentration
without significant interference on NK and Treg numbers.
In MyeloDysplastic Syndromes model, the study focused on HLA-E and HLA-I molecules, key elements for NK and Cytotoxic T cell recognition. We consistently found that a subgroup of Low and Int-1 Risk MDS patients,
categorised according with their altered immune profile, (low Treg level and
high CD54 expression on CD8 T cell effectors in BM) showed significant decrease of HLA-I expression on peripheral PMN. This observation indicate
the occurrence of CD8-dependent selection in BM. In addiction, the presence
of polyclonal NK expansion bearing an activating receptor able to recognise
HLA-E in BM has been observed to associate with the selection of dysplastic
precursors lacking HLA-E expression.
In chronic infection model, as represented by natural infection by
Leishmania Infantum in dogs we described a significant increase of CTL and
TH1 cells accompanied by reduction of Tregs. The possibility that such
condition might be relevant for the occurrence of autoimmune platelet
deficiency, frequently observed in Leishmania infected dogs has been
hypothesised. In this model, pharmacological treatment associated with
administration of a diet supplemented with nutraceuticals selected for their
potential immune modulating properties and rich in essential fatty acids was
observed to induce restoration of Treg and a progressive decrease of TH1 CD4+ T cells. The possibility that such immune-modulating effects could affect the occurrence of immune-mediated platelet deficiency is currently under investigation.
In SOD1 model, we suggested that SOD-1 is part of the network of molecules involved in antigen-dependent T cell response. Indeed, we described that antigen-dependent activation of human T lymphocytes significantly increased extracellular SOD-1 levels in lymphocyte cultures. This effect was  accompanied by the synthesis of SOD-1-specific mRNA and by the induction
of microvesicle SOD-1 secretion. Moreover, confocal microscopy showed that
antigen-dependent activation was able to modify SOD-1 intracellular
localization in T cells, allowing association of the enzyme with the intracellular network of signalling molecules involved in TCR-dependent signal transduction processes.
 The possibility that such observation might indicate the involvement of peroxide/superoxide balance in fine tuning of TCR triggering, needs further investigation.
title: Rasmussen Encephalitis
Creators: name: Boski, Neha
Publisher: name: EURORAD
Year: 2020
Subjects: subject: Neuroradiology
subject: Anatomy
subject: CNS
subject: MR
subject: Seizure disorders
subject: Clinical Cases

description: Clinical History: A 10-year-old boy presented with recurrent focal seizures since the age of six, followed by progressive left sided weakness and mild cognitive decline. Now, even after treatment with anti-epileptic drugs, patient has continuous movement of tongue, lower lip, and left thumb suggestive of epilepsia partialis continua. Electroencephalogram showed unilateral right hemispheric slowing.

description: 10 years, male
Dipole description of inclusive particle production
Creators: name: Kopeliovich, B. Z.
name: Schmidt, Ivan
name: Tarasov, A. V.
name: Voskresenskaya, O. O.
Publisher: name: arXiv
Year: 2006
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The effects of multiple interactions in colliding particles (e.g. in nucleus-nucleus collisions) are modeled using the light-cone dipole approach. Guided by the abelian analogue of multi-photon interactions in the production of a pair of charged particles, we relate the inclusive cross section of quark pair production with the cross sections of interaction of a QCD dipole with either the beam or the target.
description: Latex, 11 pages, 2 figures
DeepSeqSLAM: A Trainable CNN+RNN for Joint Global Description and Sequence-based Place Recognition
Creators: name: Chancán, Marvin
name: Milford, Michael
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Sequence-based place recognition methods for all-weather navigation are well-known for producing state-of-the-art results under challenging day-night or summer-winter transitions. These systems, however, rely on complex handcrafted heuristics for sequential matching - which are applied on top of a pre-computed pairwise similarity matrix between reference and query image sequences of a single route - to further reduce false-positive rates compared to single-frame retrieval methods. As a result, performing multi-frame place recognition can be extremely slow for deployment on autonomous vehicles or evaluation on large datasets, and fail when using relatively short parameter values such as a sequence length of 2 frames. In this paper, we propose DeepSeqSLAM: a trainable CNN+RNN architecture for jointly learning visual and positional representations from a single monocular image sequence of a route. We demonstrate our approach on two large benchmark datasets, Nordland and Oxford RobotCar - recorded over 728 km and 10 km routes, respectively, each during 1 year with multiple seasons, weather, and lighting conditions. On Nordland, we compare our method to two state-of-the-art sequence-based methods across the entire route under summer-winter changes using a sequence length of 2 and show that our approach can get over 72% AUC compared to 27% AUC for Delta Descriptors and 2% AUC for SeqSLAM; while drastically reducing the deployment time from around 1 hour to 1 minute against both. The framework code and video are available at https://mchancan.github.io/deepseqslam
description: 9 pages, 6 figures, 2 tables
Automated tuning of paper machine cross-directional feedback controllers
Creators: name: Zhang, Ming
Publisher: name: University of British Columbia
Year: 2009

description: Automatic tuning of the feedback controllers in a commercial paper machine CD control system is considered in this thesis. A feedback controller tuning tool has been designed and developed for tuning the Dahlin controller and control filter in the Honeywell-Measurex CD control system. This tool includes the process identification module, the disturbance identification module and the controller and filter tuning module. The tool is coded in MATLAB and some algorithms have been implemented as "C" modules embedded into a product currently on the market. The tuning strategy used in this tool is based on modern system identification and controller parameter optimization techniques. A global search method combined with the Levenberg- Marquardt refinement is used for identification of the paper machine time-response model (first order plus delay). To obtain a longer disturbance realization sequence and increase data available for identification of the process disturbance, CD residuals, extracted from bump test data, are used for identifying an Integrated Moving Average disturbance model. The identification method is based on the Recursive Extended Least Squares. Based on the identified process and disturbance models, the Dahlin controller and control filter are tuned to minimize a LQG based performance index. Since disturbance dynamics for a paper machine vary with time and with the operating conditions, the possible changes of the disturbance characteristics should be taken into account in the developed tuning algorithms. In the modified tuning scheme, the controller and filter are tuned in such a way that a performance lower bound is guaranteed for all disturbances in a certain set. The feedback controller tuning algorithms were tested extensively using simulation models, Honeywell-Measurex Devron hardware-in-the-loop paper machine simulator and many sets of mill data. A mill trial was carried out for validation of the disturbance identification and control loop variation prediction. Simulation and mill data tests showed that the developed identification algorithms were applicable to real-life mill data and the process variations were predicted with satisfactory accuracy. For better tractability of problem, in the developed algorithms it was assumed that the disturbances in adjacent zones were independent and the actuator response was narrow (about 1 or 2 zones wide). In most cases, the developed algorithms gave reasonable tuning parameters as long as these assumptions held. Validation using mill data also showed that the modified tuning algorithm sometimes overestimated the process and actuator variances and resulted in too conservative a tuning.
Thermodynamically stable skyrmion lattice in tetragonal frustrated antiferromagnet with dipolar interaction
Creators: name: Utesov, Oleg I.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Motivated by recent experimental results on GdRu$_2$Si$_2$ [Khanh, N.D., Nakajima, T., Yu, X. et al., \emph{Nat. Nanotechnol.} \textbf{15}, 444-449 (2020)], where nanometric square skyrmion lattice was observed, we propose simple analytical mean-field description of the high-temperature part of the phase diagram of centrosymmetric tetragonal frustrated antiferromagnets with dipolar interaction in the external magnetic field. In the reciprocal space dipolar forces provide momentum dependent biaxial anisotropy. It is shown that in tetragonal lattice in the large part of the Brillouin zone for mutually perpendicular modulation vectors in the $ab$ plane this anisotropy has mutually perpendicular easy axes and collinear middle axes, what leads to double-Q modulated spin structure stabilization. The latter turns out to be a square skyrmion lattice in the large part of its stability region with the topological charge $\pm 1$ per magnetic unit cell, which is determined by the frustrated exchange coupling, and, thus, nanometer-sized. In the presence of additional single-ion easy-axis anisotropy, easy and middle axes can be swapped, which leads to different phase diagram. It is argued that the latter case is relevant to GdRu$_2$Si$_2$.
description: 11 pages, 5 figures
Open Innovation - Die Chancen der Digitalisierung für die Integration von Kunden in Innovationsprozesse
Creators: name: Peschl, Anika
Publisher: name: aw&I Conference
Year: 2018

description: Ein wachsender Anteil der Betriebe öffnet seine Innovationsprozesse, um durch die Vernetzung von Wissen die Innovationsfähigkeit zu erweitern und Produktentwicklungszyklen zu verkürzen. Auch um einen genauen Fit zwischen einem Produkt und den Kundenbedürfnissen herzustellen, nutzen Unternehmen vermehrt die Möglichkeit der Kundenintegration in den Innovationsprozess. Dabei entstehen im Zuge der fortschreitenden Digitalisierung ganz neue Möglichkeiten. Da Interaktionen einen wichtigen Erfolgsfaktor für eine gewinnbringende Kundenintegration darstellen, können neue Technologien als Instrumente zur Verbesserung des Austauschs dienen. Vor diesem Hintergrund wird dargelegt, wie virtuelle Communities, virtuelle Stimuli sowie mobile Endgeräte die digitale Kundenintegration in den Innovationsprozess unterstützen können. Anhand der erarbeiteten Vor- und Nachteile verschiedener Instrumente zur Kundenintegration wird diskutiert, in welcher Form durch die Digitalisierung die Quantität und Qualität von Interaktionen bei der Kundenintegration in den Innovationsprozess erhöht werden kann und wo es Einschränkungen geben könnte.
description: aw&I Conference, Bd. 3 (2018): innteract2018
Colloidal crystal growth at externally imposed nucleation clusters
Creators: name: van Teeffelen, Sven
name: Likos, Christos N.
name: Löwen, Hartmut
Publisher: name: arXiv
Year: 2008
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We study the conditions under which and how an imposed cluster of fixed colloidal particles at prescribed positions triggers crystal nucleation from a metastable colloidal fluid. Dynamical density functional theory of freezing and Brownian dynamics simulations are applied to a two-dimensional colloidal system with dipolar interactions. The externally imposed nucleation clusters involve colloidal particles either on a rhombic lattice or along two linear arrays separated by a gap. Crystal growth occurs after the peaks of the nucleation cluster have first relaxed to a cutout of the stable bulk crystal.
description: 4 pages, accepted for publication in Phys. Rev. Lett
title: Enterococcus nephritis without pyelitis in a 11 years-old child: US and MR diagnosis
Creators: name: Dacher, Jean-Nicolas
Publisher: name: EURORAD
Year: 2020
Subjects: subject: Paediatric radiology
subject: Kidney
subject: Paediatric
subject: MR-Diffusion/Perfusion
subject: Ultrasound-Colour Doppler
subject: Clinical Cases

description: Clinical History: We report on the case of a previously healthy 11 years-old boy who was referred to our centre with a 48-hours history of progressively increasing abdominal pain. The child was febrile at 40 degrees. Nonbilious emesis was observed. On admission, the pain was located at both right flank and right iliac fossa with neither guarding nor rigidity. Initial laboratory values were as follows: CRP 27mg/L; white blood cell count 15G/L with neutrophils at 13G/L. Urinary dipstick was positive for proteins (2+) but negative for leukocytes and nitrites. A first US examination performed in emergency showed no argument for acute appendicitis. Chest radiograph was normal. Surgery was postponed and it was decided to redo US on the next day, the child being otherwise stable.

description: 11 years, male
title: Non invasive mechanical ventilation as a rare cause of pulmonary barotrauma in course of COVID 19.
Creators: name: Botti, Paolo
Publisher: name: EURORAD
Year: 2020
Subjects: subject: Chest imaging
subject: Lung
subject: CT
subject: Lung
subject: Infection
subject: Clinical Cases

description: Clinical History: A 59-year-old patient with no co-morbidities was admitted to hospital with a two weeks history of fever, cough and dyspnoea. A chest x ray documented bilateral subpleural infiltrates consistent with pneumonia. Arterial blood gas test was compatible with mild ARDS. A RT-PCR from a nasopharyngeal swab confirmed a SARS-CoV-2 infection. 

description: 59 years, male
Letter from W. R. Megaw to "Gentlemen" at Rainbow Ranche, April 5, 1910
Creators: name: Megaw, W.R.
Publisher: name: The University of British Columbia
Year: 2017

description: Letter to "Gentlemen" at Rainbow Ranche from W. R. Megaw, dated April 5, 1910, advising them that their John Deere has not arrived yet.
Additional file 2 of Phylogeny of Merlin’s grass (Isoetaceae): revealing an “Amborella syndrome” and the importance of geographic distribution for understanding current and historical diversity
Creators: name: Larsén, Eva
name: Wikström, Niklas
name: Khodabandeh, Anbar
name: Rydin, Catarina
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2. Appendix S1. List of taxon names, distributions, DNA voucher information (including area and year of collection), lab identity numbers, and accession numbers for sequences used in the analyses. Appendix S2. Primer information.
title: COVID-19 infection with isolated gastrointestinal symptoms
Creators: name: Golshan, Maryam
name: Houshyar, Roozbeh
Publisher: name: EURORAD
Year: 2020
Subjects: subject: Chest imaging
subject: Respiratory system
subject: Thorax
subject: CT
subject: Respiratory system
subject: Thorax
subject: Infection
subject: Clinical Cases

description: Clinical History: A previously healthy 47-year-old male presented with a 1-week history of fever, vomiting, nausea, and epigastric pain. Laboratory studies were notable for lymphopenia (0.8×103/µL, normal range 0.9×103/µL – 3.3×103/µL). Vitals signs were remarkable only for low-grade fever (37.9°C). He reported no respiratory complaints or known sick contacts.

description: 47 years, male
Editorial Article
Creators: name: Tudevdagva, Uranchimeg
name: Vitay, Julien
name: Nassour, John
Publisher: name: Embedded Selforganising Systems
Year: 2018

description: The world we are living in changes extremely fast, as technology is improving at an unseen pace. Smart mobile devices were luxury devices just a few years ago, while many people simply cannot imagine their daily life without them today. Robots are nowadays leaving the industrial or laboratory environments to reach people’s homes, schools and workplaces, opening new opportunities for applications of embedded systems.
description: Embedded Selforganising Systems, Vol 5 No 2 (2018): Robotics in Human Environment: Challenges and Solutions
Cognitive and Behavioral Development Among Children Prenatally Exposed to Substances: An Examination of Models of Risk
Creators: name: SHEPERD RIOLO, KELLY A.
Publisher: name: Maryland Shared Open Access Repository
Year: 2011
Subjects: behavior
cumulative risk
intelligence
prenatal drug exposure

description: The combined effects of drug exposure and environmental adversity may have important implications for several developmental outcomes. The existent literature presents mixed findings regarding the direct effect of cumulative risk among drug exposed samples on cognitive and behavioral outcomes. The present research was divided into two studies to examine the nature of the relation between cumulative risk during the first year of life and cognitive and behavioral outcomes at 60 months. Both studies used a sample of 132 primarily low-income African American children exposed to cocaine (30.8%), heroin (14.0%), or both (55.1%).  The first study examined cumulative risk using four models: cumulative risk, threshold effects, specific indices, and unique effects. There were no direct linear or nonlinear relations between cumulative risk with cognitive or behavioral outcomes. There was a direct association between psychosocial risk (specifically negative life events) with both internalizing and externalizing behaviors. None of the models of risk were associated with intelligence.   The second study examined process variables (mental development scores, harsh caregiving, and caregiver change) to determine whether proximal risk factors may explain the relation between cumulative risk and cognitive and behavioral development. The results of the second study suggested that mental development scores at 12, 18, 24, and 30 months were predictive of intelligence at 60 months, but not behavior. Harsh caregiving was directly associated with internalizing behaviors, and moderated the relation between cumulative risk and internalizing behaviors. Finally, the number of caregiver changes from birth-60 months was associated with greater attention problems at 60 months. Overall, the findings from the present study provide little support for an association between cumulative risk with developmental outcomes within a drug exposed sample. The overall cognitive scores were very low and not associated with any risk factors, suggesting that the present sample was relatively low functioning, cognitively. Psychosocial risk was associated with behavior problems, especially caregiver negative life events and harsh caregiving. These findings suggest that the caregiving environment represents an important context for behavioral development. Implications for theory, practice, and policy are discussed.
Chondrocladia Thomson 1873
Creators: name: Ekins, Merrick
name: Hooper, John N. A.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Porifera
Demospongiae
Poecilosclerida
Cladorhizidae
Chondrocladia

description: Subgenus Chondrocladia Thomson, 1873
Diagnosis: Chondrocladia without a layer of special spicules (subtrochirhabds or trochirhabds), lacking special rostriform (snoutlike) subtylostyles in filaments or terminal balls, and without planar vanes formed of evenly spaced upright branches (from Lee et al., 2012).
Type species: Chondrocladia virgata Thomson, 1873 (by monotypy).
Remarks. The genus Chondrocladia was summarised in Table 6 of Lopes et al. (2011), and updated to include additional information and recently described species in Table 10 in Ekins et al. (2020a).
description: Published as part of Ekins, Merrick & Hooper, John N. A., 2023, New carnivorous sponges from the Great Barrier Reef, Queensland, Australia collected by ROV from the RV FALKOR, pp. 435-471 in Zootaxa 5293 (3) on page 437, DOI: 10.11646/zootaxa.5293.3.2, http://zenodo.org/record/7961272
Artificial Intelligence & Machine Learning in Computer Vision Applications
Creators: name: Saleh, Shadi
Publisher: name: Embedded Selforganising Systems
Year: 2020

description: Deep learning and machine learning innovations are at the core of the ongoing revolution in Artificial Intelligence for the interpretation and analysis of multimedia data. The convergence of large-scale datasets and more affordable Graphics Processing Unit (GPU) hardware has enabled the development of neural networks for data analysis problems that were previously handled by traditional handcrafted features. Several deep learning architectures such as Convolutional Neural Networks (CNNs), Recurrent Neural Networks (RNNs), Long Short Term Memory (LSTM)/Gated Recurrent Unit (GRU), Deep Believe Networks (DBN), and Deep Stacking Networks (DSNs) have been used with new open source software and libraries options to shape an entirely new scenario in computer vision processing.
description: Embedded Selforganising Systems, Vol 7 No 1 (2020): Artificial Intelligence & Machine Learning in Computer Vision Applications
How to write an article for GAMMAS and a longer title
Creators: name: Kern, Dominik
name: Bartelt, Matthias
name: Unger, Benjamin
Publisher: name: GAMM Archive for Students
Year: 2019

description: This template is a ready-to-run example article you may substitute with your own content.
Moreover it contains information about some journal policies.
description: GAMM Archive for Students, Vol 1 No 1 (2019): GAMMAS - The First Year
Higher-order exponential integrators for constrained semi-linear parabolic problems
Creators: name: Wiedemann, Johannes
Publisher: name: GAMM Archive for Students
Year: 2020

description: This paper provides an introduction to exponential integrators for constrained parabolic systems. In addition, building on existing results, schemes with an expected order of convergence of three and four are established and numerically tested on parabolic problems with nonlinear dynamic boundary conditions. The simulations reinforce the subjected error behaviour.
description: GAMM Archive for Students, Vol 2 No 1 (2020): GAMMAS - The second year
title: Neovaginal obstruction secondary to introitus stenosis.
Creators: name: De Llano Ibisate, Loreto Ana
name: Unzue Garcia-Falces, Guillermo
name: López Sala, Paul
name: Alberdi Aldasoro, Nerea
name: Vicaría, Iván
name: Lajusticia Andrés, Héctor
Publisher: name: EURORAD
Year: 2020
Subjects: subject: Genital (female) imaging
subject: Abdomen
subject: CT
subject: Complications
subject: Computer Applications-General
subject: Obstruction / Occlusion
subject: Clinical Cases

description: Clinical History: A 38-year-old patient with sex reassignment surgery (Vaginal Reconstruction with Sigmoid Colon), came to the Emergency room for abdominal pain located in the hypogastrium. She referred vaginal introitus stenosis for years as a complication of surgery, being impossible to perform a gynaecological examination or have sexual relations.

description: 38 years, male
Frank & Susan Lobo Sound Recordings of the Juaneño Language
Creators: name: Majel, Abel
name: Lobo, Frank
name: Lobo, Susan
name: Brown, Maria
name: Portela De Lobo, Rita
Publisher: name: California Language Archive, University of California, Berkeley
Year: 2022

description: Discussion among family members, personal history, and elicitation of lexical items and basic phrases
Die Weltmissionskonferenz in Arusha (Tansania) und die Missionserklärung "Gemeinsam für das Leben"
Creators: name: Biehl, Michael
Publisher: name: Ökumenische Rundschau
Year: 2025

description: Ökumenische Rundschau, Bd. 67 Nr. 3 (2018): Ökumenische Rundschau, Band 67, Heft 3
Quantifying Uncertainty in Infectious Disease Mechanistic Models
Creators: name: McGowan, Lucy D'Agostino
name: Grantz, Kyra H.
name: Murray, Eleanor
Publisher: name: arXiv
Year: 2021
Subjects: subject: Methodology (stat.ME)
subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: This primer describes the statistical uncertainty in mechanistic models and provides R code to quantify it. We begin with an overview of mechanistic models for infectious disease, and then describe the sources of statistical uncertainty in the context of a case study on SARS-CoV-2. We describe the statistical uncertainty as belonging to three categories: data uncertainty, stochastic uncertainty, and structural uncertainty. We demonstrate how to account for each of these via statistical uncertainty measures and sensitivity analyses broadly, as well as in a specific case study on estimating the basic reproductive number, $R_0$, for SARS-CoV-2.
description: American Journal of Epidemiology, 2021
Carotid Intimal Medial Thickness and Cognitive Function: The Baltimore Longitudinal Study of Aging
Creators: name: Wendell, Carrington Rice
Publisher: name: Maryland Shared Open Access Repository
Year: 2010
Subjects: atherosclerosis
carotid intimal medial thickness
cognitive function
neuropsychology
subclinical vascular disease

description: Though clinical cardiovascular and cerebrovascular diseases are established risk factors for cognitive decline and dementia, less is known about the relations between vascular health and cognition among individuals without these diseases. Carotid intimal medial thickness (IMT), a measure of subclinical vascular disease, is associated with concurrent decrements in cognitive function, but relatively little research has examined relations between carotid IMT and prospective cognitive decline. The present investigation examined associations between carotid IMT and cognitive function, both cross-sectionally and longitudinally, among 538 participants (aged 20 to 93, 39% male, 66% white) in the Baltimore Longitudinal Study of Aging free of known cardiovascular, cerebrovascular, and neurological disease. Participants underwent initial carotid ultrasonography and repeat neuropsychological testing on up to eight occasions over up to 11 years of follow-up. Mixed-effects regression analyses were adjusted for age, gender, race, education, mean arterial pressure, body mass index, total cholesterol, smoking, depressive symptoms, and cardiovascular medication use. Significant cross-sectional associations between carotid IMT and cognitive performance were largely qualified by significant longitudinal associations. In contrast to those individuals with lesser carotid IMT values, individuals with greater carotid IMTs displayed accelerated decline in performance over time on multiple tests of verbal and nonverbal memory, as well as a test of semantic association fluency and executive function. These findings underscore the importance of early intervention to delay or reduce atherosclerosis and improve vascular health before symptom manifestation. Such intervention (e.g., pharmacological, behavioral) may delay onset of cognitive decline, slow cognitive aging, and perhaps delay or protect against clinical cognitive diagnoses.
Electrostatic theory of viral self-assembly: a toy model
Creators: name: Hu, Tao
name: Zhang, Rui
name: Shklovskii, B. I.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Biomolecules (q-bio.BM)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Viruses self-assemble from identical capsid proteins and their genome consisting, for example, of a long single stranded (ss) RNA. For a big class of T = 3 viruses capsid proteins have long positive N-terminal tails. We explore the role played by the Coulomb interaction between the brush of positive N-terminal tails rooted at the inner surface of the capsid and the negative ss RNA molecule. We show that viruses are most stable when the total contour length of ss RNA is close to the total length of the tails. For such a structure the absolute value of the total RNA charge is approximately twice larger than the charge of the capsid. This conclusion agrees with structural data.
description: 4 pages, 2 figures
Associations among a Set of Motivational Variables, Self-Management Behaviors and Glycemic Control in a Sample of African-Americans with Type 2 Diabetes
Creators: name: Gemmell, Leigh Anne
Publisher: name: Maryland Shared Open Access Repository
Year: 2008
Subjects: Psychology, Clinical (0622)
diabetes
motivation
readiness
self-efficacy
importance
self-management

description: The purpose of this cross-sectional study was to examine the associations among a set of motivational variables (readiness, importance, and self-efficacy), self-management behaviors (diet, exercise/physical activity) and glycemic control in a sample of adults with diabetes.  Participants were 76 African-American adults with type 2 diabetes.  The following information was collected via orally administered questionnaires: demographics, comorbidities and complications, self-management behaviors, readiness to change each self-management behavior, self-efficacy for each self-management behavior, importance of each self-management behavior.  Participant's body mass index was measured and a blood sample was collected in order to assess hemoglobin A1C level (A1C).  There was a unique effect of physical activity/exercise on A1C (Beta-weight = -.242, p=.04).  The full set of motivational variables for each self-management behavior predicted level of glycemic control for diet (Chi-square = 13.83, p
Ideenmanagement: Was ist der Stand? Was bringt die Zukunft?
Creators: name: Schat, Hans-Dieter
Publisher: name: aw&I Conference
Year: 2018

description: Ideenmanagement kann als Zusammenfassung von Betrieblichem Vorschlagswesen und Kontinuierlichem Verbesserungsprozess verstanden werden und als ein Schritt auf dem Weg zum integrierten Managementsystem. Ideenmanagement wird in vielen Organisationen eingesetzt, in der Wissenschaft aber selten thematisiert. Für diesen Aufsatz werden die Daten einer Erhebung des Ideenmanagements bei 261 Organisationen herangezogen, dies ist der größte aktuelle Datensatz über das Ideenmanagement im deutschsprachigen Raum. Im ersten Teil des Aufsatzes werden Erfolgskennzahlen (rechenbarer Nutzen pro Beschäftigte und Jahr, Beteiligungsquote etc.) und Strukturkennzahlen (Bearbeitungszeiten, Anzahl der Ideenmanager pro 1000 Beschäftigte etc.) vorgestellt. Im zweiten Teil des Aufsatzes wird berichtet, wie die Ideenmanager zukünftige Trends (Gamification, Industrie 4.0 / Arbeit 4.0 etc.) einschätzen. Dabei werden die Einschätzungen erfolgreicher Ideenmanager denjenigen ihrer weniger erfolgreichen Kollegen gegenübergestellt. Wenn „Erfolg“ ein zeitlich stabiles Phänomen ist, dann sollten die Einschätzungen der erfolgreichen Ideenmanager eine größere Trefferquote zeigen.
description: aw&I Conference, Bd. 3 (2018): innteract2018
title: COVID-19 patient with a remarkable increase in D-Dimer values and suspicion of pulmonary embolism
Creators: name: Chávez Marroquin, Luis
name: Auban Pariente, Rocio
name: Vaño Molina, Maria
Publisher: name: EURORAD
Year: 2020
Subjects: subject: Chest imaging
subject: Lung
subject: Pulmonary vessels
subject: Thorax
subject: Infection
subject: Lung
subject: Thorax
subject: Infection
subject: Clinical Cases

description: Clinical History: A 65-year-old male patient with a past medical history of hypertension and dyslipidemia presented to the emergency department with a 5-day history of cough and fever, associated with dyspnoea in the last 48 hours. Initial laboratory tests showed a normal white cell count, elevated C-reactive protein (118 mg/L, normal range 0-5 mg/L), elevated D-dimer (1,0 mcg/ml, normal range 0-0,5 mcg/ml), elevated interleukin-6 (76,6 pg/ml, normal range < 3,4 pg/ml) and elevated ferritin (1639 ng/ml, normal range 22-322 ng/ml). The day after admission the patient developed acute respiratory distress, was emergently intubated and transferred to the ICU.

description: 65 years, male
The dispersion measure and scattering of FRBs: Contributions from the intergalactic medium, foreground halos, and hosts
Creators: name: Zhu, Weishan
name: Feng, Long-Long
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We investigate the dispersion measure(DM) and scattering of FRBs by the intergalactic-medium(IGM), foreground and host halos, using cosmological hydrodynamical simulation. We find that the median DM caused by foreground halos is around 30\% of that caused by the IGM, but has a much larger variance. The DM induced by hosts deviates from a log-normal distribution, but exhibits an extended distribution in the range of $1-3000 \ {\rm{pc\, cm^{-3}}}$ with a median value $\sim 100 \ {\rm{pc\, cm^{-3}}}$. Then we produce mock FRB sources, assuming a uniform distribution in the range $z\sim 0-0.82$, to consider the propagation effect of IGM, foreground and host halos on FRB signals simultaneously. The DM distribution of mock sources agrees well with the observation. The fitted DM-redshift relation of the mock sources can provide a rough estimation of the redshifts of observed events with errors $δz \lesssim 0.15$. The distribution of mock sources in the DM-scattering time($τ$) space can also match the observation, assuming a Kolmogorov turbulence model with the inner and outer scale is 1000 km to 1 AU, and 0.2-10 pc respectively. Finally, we estimate the relative importance of these medium on DM and $τ$ in our models. The IGM and host halos are the primary and secondary sources to the extragalactic DM, $\rm{DM_{exg}}$. Meanwhile, the contribution from foreground halos increases as $\rm{DM_{exg}}$ increases. The host and foreground halos may be the most important medium for scattering. Statistically, the latter may dominate the scattering of events with $\rm{DM_{exg}} \gtrsim 200 \ {\rm{pc\, cm^{-3}}}$.
description: 21 pages, 13 figures. Accepted for publication in ApJ
Gretchen S. Hillard Sound Recordings of the Central Pomo Language
Creators: name: Bartlett Alcantra, Salome
name: Parrish, Sidney
name: Hillard, Gretchen S.
Publisher: name: California Language Archive, University of California, Berkeley
Year: 2022

description: Twenty nine WAV files digitized from twenty two reels; extensive elicitation of lexical items and sentences targeting various grammatical domains; some narrative texts
title: An uncommon cause of urinary obstruction.
Creators: name: Janne d'Othee, Bertrand
Publisher: name: EURORAD
Year: 2020
Subjects: subject: Interventional radiology
subject: Interventional non-vascular
subject: Kidney
subject: Urinary Tract / Bladder
subject: CT
subject: Fluoroscopy
subject: Percutaneous
subject: Diagnostic procedure
subject: Drainage
subject: Pyelography
subject: Cysts
subject: Obstruction / Occlusion
subject: Clinical Cases

description: Clinical History: A 71-year-old man presented with fever, tachycardia, hypoxia, elevated white blood cell count, lactic acidosis and sepsis. Non-contrast CT demonstrated right-sided hydronephrosis with suspicion of obstructive uropathy and infected urolithiasis. Patient is not a surgical candidate given his respiratory status, morbid obesity, type 2 diabetes mellitus and hypertension. Percutaneous nephrostomy is requested.

description: 71 years, male