cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplementary Material for: Inhibitor of Differentiation 3, a Transcription Factor, Regulates Hyperlipidemia-Associated Kidney Disease
Creators: name: Nackiewicz, D.
name: Dey, P.
name: Szczerba, B.
name: Mohammad, S.
name: Kaplan, J.L.
name: McNamara, C.A.
name: Deshmukh, U.S.
name: Bagavant, H.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background: Lipoprotein abnormalities are associated with a rapid decline in renal function in patients of chronic kidney disease. In addition, hyperlipidemia is associated with an increased risk of developing renal insufficiency. The underlying molecular mechanisms for these clinical findings are unclear. We have previously reported a role for inhibitor of differentiation 3 (ID3), a transcription factor, in regulating kidney disease in hyperlipidemia. Introducing a genetic deficiency of Id3 in spontaneously hyperlipidemic apolipoprotein E knockout (Apoe-/-) mice led to accelerated mesangioproliferative glomerulonephritis. The present study was carried out to further investigate the contribution of ID3 in hyperlipidemia-associated kidney disease. Methods: Female C57BL/6 mice that were ID3-sufficient wild-type (WT) or ID3-deficient (Id3-/-) were fed a Western diet and evaluated for proteinuria, glomerular pathology, and immune infiltrating cells. Primary mesangial cell lines were generated from both mouse strains and stimulated with oxidized phospholipids. Cytokines and chemokines produced were measured by multiplex assays, ELISA, and QPCR. Glomerular isolates were studied for CXCL1 expression by QPCR. Results:Id3-/- mice on a Western diet developed accelerated proteinuria and mesangioproliferative glomerulonephritis compared to WT controls. In vitro, Id3-/- glomerular mesangial cell lines produced higher levels of the monocyte chemoattractant CXCL1 in response to oxidized phospholipids. This was consistent with the rapid increase in glomerular CXCL1 expression followed by macrophage infiltration in Id3-/- mice fed a Western diet. Conclusions: A functional ID3 influences susceptibility to kidney disease and prevents glomerular injury by regulating local chemokine production and inflammatory cell recruitment.
A new lactam alkaloid from Portulaca oleracea L. and its cytotoxity
Creators: name: Chengcheng Zhao
name: Zheming Ying
name: Xiaojun Tao
name: Mingyue Jiang
name: Xixiang Ying
name: Guanlin Yang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: A new lactam alkaloid named oleraciamide D (1), indentified as (5R)-4-(3-methoxy-4-hydroxyphenyl)-5-(4-hydroxyphenyl)-5,6-dihydropyridin-2(1H)-one, together with five known compounds, indole-3-aldehyde (2), portulacatone (3), N-trans-feruloyloctopamine (4), N-trans-feruloyl-3′-O-methyldopamine (5) and N-trans-feruloyltyramine (6) were isolated from Potulaca oleracea L. Among them, indole-3-aldehyde (2) was isolated from the medicine for the first time. The structure of the new alkaloid was elucidated via UHPLC-ESI-Q-TOF/MS, 1D NMR and 2D NMR. The five known compounds were established by comparing the 1H-NMR and 13C NMR with the reported literature. Oleraciamide D (1) showed cytotoxicity against SH-SY5Y cells when concentration at 50 uM by CCK-8 method.
A Traverso le Foglie: Design Brief for a DH Project on the Poems of Ezra Pound
Creators: name: Lippincott, Sarah
Publisher: name: figshare
Year: 2017
Subjects: Literature

description: In the introduction to a 1920 essay, “The Reputation of Ezra Pound,” May Sinclair declared,
If the views of some of our more conservative reviewers were immortal Posterity would have an odd idea of Ezra Pound. It would know him, if it were allowed to know him at all, as a literary mountebank; a masquerader looking for something to wear, ransacking the wardrobes of every century but his own; an impudent schoolboy letting off squibs in his back garden.
Even in 1920, Ezra Pound had a complex and tense relationship with critics and other audiences. The scholarly discourse continues to tease out the relationship between Pound and his political beliefs and actions, and his literary accomplishments. “A traverso le foglie: New ways of looking at Ezra Pound” uses this relationship as a foundation for inspiring new ways of looking at Pound. It brings together an interactive digital reading environment, a tool for browsing annotations, and a timeline that charts critical and public reception of Pound throughout his controversial lifetime and up to the present. It aims to both provide a reading environment that enhances the experience and understanding of the poem itself (and thereby assert the significance of the text as a work of art), and to explore the relationship between the author’s life (i.e. political convictions and actions) and his artistic production. This brief describes the decisions and reflection that informed each component of the project, lingering questions and concerns, and intended outcomes for the project.
Endothelial function in patients with chronic obstructive pulmonary disease: a systematic review of studies using flow mediated dilatation
Creators: name: Vaes, Anouk W.
name: Spruit, Martijn A.
name: Theunis, Jan
name: Nandu Goswami
name: Vanfleteren, Lowie E.
name: Franssen, Frits M.E.
name: Wouters, Emiel F.M.
name: Boever, Patrick De
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Background: Cardiovascular disease is an important cause of morbidity and mortality in chronic obstructive pulmonary disease (COPD). Endothelial function may be involved in the pathogenesis of cardiovascular disease. In contrast to the attention given to pulmonary endothelial dysfunction, little is known about peripheral vascular changes in COPD. Therefore, we reviewed the literature on peripheral endothelial function in COPD. Methods: Databases were screened for studies using ultrasound-based flow-mediated dilation (FMD), the reference method for assessing peripheral endothelial function, in stable COPD patients. Pooled effect sizes were calculated using random effects model. Results: 17 studies were identified, with a total of 1228 participants (724 COPD patients; 504 controls). Pooled analysis demonstrated an impaired endothelial-dependent FMD (−3.22%; 95% confidence interval (CI) −4.74 to −1.69; p 2 = 96%) and endothelial-independent FMD (−2.86%; 95%CI −5.63 to −0.09; p = 0.04; I2 = 83%) in COPD patients when compared with smoking and non-smoking controls. Conclusion: This review provides evidence for impaired peripheral endothelial function in COPD. Since impaired endothelial function may contribute to cardiovascular morbidity, a more comprehensive cardiovascular phenotyping is considered important in COPD to address cardiovascular risk. A high frequency of cardiovascular comorbidity is observed in COPD patients, and therefore well-controlled, larger studies that investigate endothelial function in COPD patients are recommended.
Maleic anhydride and chromone derivatives from the endophytic fungus BCC 54265 (Botryosphaeriaceae)
Creators: name: Isaka, Masahiko
name: Somporn Palasarn
name: Sujinda Sommai
name: Pattiyaa Laksanacharoen
name: Kitlada Srichomthong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: A maleic anhydride derivative, botryoanhydride (1), and a chromone derivative, botryochromone (2), together with three known chromones, eugenitin (3), 6-hydroxymethyleugenin (4) and 6-methoxymethyleugenin (5), were isolated from cultures of the endophytic fungus BCC 54265 of the family Botryosphaeriaceae. The structures were elucidated on the basis of NMR, HRMS and CD data. Compound 2 showed weak cytotoxic activity to cancer cell-lines.
Curcumin or bisdemethoxycurcumin for nose-to-brain treatment of Alzheimer disease? A bio/chemo-informatics case study
Creators: name: Hathout, Rania M.
name: Sherweit H. El-Ahmady
name: Metwally, AbdelKader A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: The current study introduces a new idea of utilising several bio/chemoinformatics tools in comparing two bio-similar natural molecules viz. curcumin and bisdemethoxycurcumin (BDMC) in order to select a potential nose-to-brain remedy for Alzheimer disease. The comparison comprised several bio/chemo informatics tools. It encompassed all levels starting from loading the drug in a certain carrier; PLGA nanoparticles, to the biopharmaceutical level investigating the interaction with mucin and inhibition of P-gp blood–brain barrier efflux pumps. Finally, the therapeutic level was investigated by studying the interaction with pharmacological targets such as amyloid peptide plaques and cyclooxygenase2 enzyme responsible for the inflammatory reactions of the studied disease. The comparison revealed the superiority of curcumin over BDMC. Five new analogues were also hypothesised where diethoxybisdemethoxycurcumin was recommended as a superior molecule. This work introduced the virtual utilisation of bio/chemo informatics tools as a reliable and economic alternative to the exhausting and resources-consuming wet-lab experimentation.
Interactions of quercetin with receptor tyrosine kinases associated with human lung carcinoma
Creators: name: Bincy Baby
name: Antony, Priya
name: Vijayan, Ranjit
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Lung cancer is a deadly form of cancer with high morbidity and mortality rates. Deregulated receptor tyrosine kinases (RTKs) are frequently associated with the formation and development of lung carcinoma. Quercetin is a major dietary flavonoid that has been shown to induce cell growth inhibition and apoptosis in human lung cancer cell lines. In the current study, four major overexpressed RTKs – EGFR, FGFR1, IGF1R and c-Met – involved in human lung cancer were investigated. Molecular docking was employed to identify the binding orientation and inhibitory potential of quercetin in these RTKs. Quercetin bound to the ATP binding pocket of these kinases exhibited good binding scores and interactions by establishing hydrogen, hydrophobic and π-π interactions with the hinge region and the DFG motif in the activation loop. Thus, quercetin could be further explored as a platform for developing specific or polypharmacological compounds targeting overexpressed RTKs in lung cancer.
Additional file 1 of Lactate kinetics in ICU patients using a bolus of 13C-labeled lactate
Creators: name: Grip, Jonathan
name: Falkenström, Tobias
name: Panuwat Promsin
name: Wernerman, Jan
name: Norberg, Åke
name: Rooyackers, Olav
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 1. Complete documentation of formulas used for mathematical modelling of data.
Chemical composition and in vitro antileishmanial and cytotoxic activities of the essential oils of Ocotea dispersa (Nees) Mez and Ocotea odorifera (Vell) Rohwer (Lauraceae)
Creators: name: Alcoba, Ana E. T.
name: Melo, Daiana C. De
name: Andrade, Priscila M. De
name: Dias, Herbert J.
name: Pagotti, Mariana C.
name: Lizandra G. Magalhães
name: Walnir G. F. Júnior
name: Antônio E. M. Crotti
name: Mayker L. D. Miranda
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry

description: We investigate the chemical composition and the in vitro antileishmanial and cytotoxic activities of the essential oils extracted from the leaves of Ocotea dispersa (Nees) Mez (OD-EO) and Ocotea odorifera (Vell) Rohwer (OO-EO). On the basis of GC-FID and GC-MS, α-eudesmol (20.9%), valencene (10.2%), δ-elemene (9.3%) and isospathulenol (7.3%) are the major constituents of OD-EO, whereas safrole (36.3%), γ-cadinene (6.6%), camphor (6.5%) and α-copaene (6.0%) are the main constituents of OO-EO. Both OD-EO and OO-EO display significant activity against the promastigote forms of Leishmania amazonensis, with IC50 values of 4.67 ± 0.95 and 11.67 ± 2.16 μg/mL, respectively. The 50% cytotoxic concentration (CC50) of OD-EO and OO-EO to mouse peritoneal macrophages is 26.77 ± 4.06 and 49.52 ± 1.04 μg/mL, respectively. This is the first report on the chemical composition of the essential oil extracted from the leaves of O. dispersa. Our results suggest that OD-EO and OO-EO are a promising source of new antileishmanial agents.
Additional file 2 of Lactate kinetics in ICU patients using a bolus of 13C-labeled lactate
Creators: name: Grip, Jonathan
name: Falkenström, Tobias
name: Panuwat Promsin
name: Wernerman, Jan
name: Norberg, Åke
name: Rooyackers, Olav
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Computational Biology

description: Additional file 2. Plasma lactate enrichment of labeled lactate for healthy volunteers and ICU patients
The inspector, the men and the mallee: Establishing a soldier settlement in 1919-20
Creators: name: Holmes, Katie
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 390107
subject: Humanities and social sciences curriculum and pedagogy (excl. economics, business and management)
classificationCode: 4407
subject: Policy and administration
classificationCode: 4408
subject: Political science
subject: FOS: Political science

description: No description supplied
Additional file 3 of Lactate kinetics in ICU patients using a bolus of 13C-labeled lactate
Creators: name: Grip, Jonathan
name: Falkenström, Tobias
name: Panuwat Promsin
name: Wernerman, Jan
name: Norberg, Åke
name: Rooyackers, Olav
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: Additional file 3. Individual values for lactate concentrations in plasma for healthy volunteers and ICU patients during experiment.
Beiträge der ILE-Förderung zu gleichwertigen Lebensverhältnissen in ländlichen Räumen
Creators: name: Dosch, Axel
name: Dosch, Axel
Publisher: name: Unknown
Year: 2022
Subjects: subject: Community/Rural/Urban Development
subject: Land Economics/Use
subject: rural development
subject: village development
subject: joint task of improving agricultural structures and coastal protection
subject: equivalent living conditions
subject: ländliche Entwicklung
subject: Dorfentwicklung
subject: Gemeinschaftsaufgabe zur Verbesserung der Agrarstruktur und Küstenschutz
subject: gleichwertige Lebensverhältnisse

description: Contributions of Integrated Rural Development measures to equivalent living conditions in rural areas The report focuses on Integrated Rural Development (IRD) measures under the Joint Task of Im-proving Agricultural Structures and Coastal Protection (Gemeinschaftsaufgabe zur Verbesserung der Agrarstruktur und des Küstenschutzes (GAK)), which are grouped together in Support Area 1 of the GAK. Recently, this support area has gained in importance both in terms of content and budget. In the debate on equivalent living conditions, contributions by the GAK are expected, above all through Integrated Rural Development measures. First the concept of living conditions is operationalised. The different measures of Integrated Rural Development are described, including their implementation and design in the Bundesländer. Then the contribution to services of general interest and the overall quality of life are described in qualitative terms. The Integrated Rural De-velopment measures address many aspects of services of general interest. They contribute to the improvement of living conditions by intensifying social relationships and personal activities as ma-jor dimensions of quality of life. Further empirical work is required for a comprehensive analysis of the effects of Integrated Rural Development measures on equivalent living conditions.
description: DOI:10.3220/WP1641909797000
Multiplex PCR assay discriminates rabbit, rat and squirrel meat in food chain
Creators: name: Ahamad, Mohammad Nasir Uddin
name: Md. Eaqub Ali
name: M. A. Motalib Hossain
name: Asing Asing
name: Sharmin Sultana
name: M. H. A. Jahurul
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Rabbit meat is receiving increasing attention because it contains a high level of proteins with relatively little fat. On the other hand, squirrel meat is served in upper-class meals in certain countries, so is sold at higher prices. The other side of the coin is rat meat, which has family ties with rabbit and squirrel but poses substantial threats to public health because it is a potential carrier of several zoonotic organisms. Recently, rat meat was mislabelled and sold as lamb after chemical modification. Thus, the chances of rabbit and squirrel meat substitution by rat meat cannot be ruled out. For the first time, a multiplex PCR assay was developed in Malaysia for the discriminatory identification of rat, rabbit and squirrel in the food chain. Rabbit (123 bp), rat (108 bp) and squirrel (243 bp) targets were amplified from ATP6 and cytb genes, along with a eukaryotic internal control (141bp). The products were sequenced and cross-tested against 22 species. A total of 81 reference samples and 72 meatball specimens were screened to validate the assay. Analyte stability was evaluated through boiling, autoclaving and micro-oven cooking. The tested lower limits of detection were 0.01 ng DNA for pure meat and 0.1% for meatballs.
1,3-Bis(pyren-1-yliminomethyl)calix[4]arene as a selective fluorescent turn-on sensor for mercury(II) ion
Creators: name: Tanaka, Shinya
name: Hirasawa, Kengo
name: Watanabe, Kyohei
name: Tetsutaro Hattori
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Plant Biology
subject: Computational Biology

description: A novel calixarene-based diimine, 1,3-bis(pyren-1-yliminomethyl)calix[4]arene (5), serves as a turn-on-type fluorescent sensor, which selectively detects Hg2+ in THF/H2O (99:1, v/v) in the presence of various other metal ions. Such selectivity is not seen with half salen 1 derived from salicylaldehyde and 1-aminopyrene. 1H NMR analysis reveals that it is a chemodosimetric sensor based on its hydrolysis mediated by Hg2+ to release 1-aminopyrene molecules as fluorescent chromophores.
Parents’ lay beliefs about interracial contact and behaviors aimed at raising antiracist children
Creators: name: Eddy, Zoey Elizabeth
Publisher: name: No Publisher Supplied
Year: 2024

description: Interracial contact is a key tool for reducing racial prejudice, including reducing children’s prejudice. Parents play a vital role in exposing their children to diversity and in the development of children’s racial attitudes. Thus, in the present study, I examined how White parents’ lay beliefs about interracial contact (i.e., whether parents are aware of the positive benefits of interracial contact for intergroup relations) relate to parents’ behaviors, including exposing their children to interracial contact. In a correlation study, 197 White parents completed a survey assessing their lay beliefs about interracial contact, indirect and direct diversity exposure behaviors, the diversity of the child’s and the parent’s social network, frequency of race discussions with one’s child, strategies to raise an antiracist child (general and interracial contact specific), importance of antiracism, bias awareness, and White privilege awareness. Analyses revealed that White parents’ lay beliefs about interracial contact are directly correlated with parents’ reports of greater engagement in indirect and direct diversity exposure behaviors, a greater frequency of race discussions and reporting a greater number of general and interracial contact specific strategies for raising an antiracist child. Lay beliefs about interracial contact were not related to the diversity of the child’s and the parent’s own social networks. Importance of antiracism and bias awareness did not moderate the relationships between lay beliefs about interracial contact and diversity exposure behaviors. This work suggests multiple avenues of future research exploring how parents’ lay beliefs may relate to reduced prejudice among their children.
Additional file 1 of Association between added sugar intake and micronutrient dilution: a cross-sectional study in two adult Swedish populations
Creators: name: González-Padilla, Esther
name: Dias, Joana A.
name: Ramne, Stina
name: Olsson, Kjell
name: Nälsén, Cecilia
name: Sonestedt, Emily
Publisher: name: figshare
Year: 2020
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Additional file 1: Table S1. Micronutrient and energy intakes by sex across the added-sugar groups in Riksmaten Adults. Table S2. Micronutrient and energy intakes by sex across the added-sugar groups in the Malmö Diet and Cancer Study.
Additional file 1 of Avatar-based versus conventional vital sign display in a central monitor for monitoring multiple patients: a multicenter computer-based laboratory study
Creators: name: Garot, Olivier
name: Rössler, Julian
name: Pfarr, Juliane
name: Ganter, Michael
name: Spahn, Donat
name: Nöthiger, Christoph
name: Tscholl, David
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Neuroscience
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Table S1. The numbers and percentages with which the participants correctly recalled the individual vital signs in the 10-s and 30-s scenarios. Each participant evaluated each vital sign a total of eight times (four times with either monitoring technology). In the 10-s scenarios, two of the 11 vital signs were more frequently recognized using conventional monitoring. In the 30-s scenarios, four of the 11 vital signs were more frequently recognized using conventional monitoring. Figure S1. Perceptive performance in the 30-s scenarios. The dotted lines represent the median number of correctly recalled vital signs, which was 16 with avatar-based monitoring and 15 with conventional monitoring (paired Student’s t-test, p = 0.055, effect size d = 0.33). Figure S2. Perceived workload in the 30-s scenarios. The dotted lines represent the median NASA-TLX score, which was 60 with avatar-based monitoring and also 60 with conventional monitoring (paired Student’s t-test, p = 0.59, effect size d = 0.13).
External validation of acute-to-chronic models for estimation of reproductive toxicity to Daphnia magna
Creators: name: A. Furuhama
name: T. I. Hayashi
name: H. Yamamoto
name: N. Tatarazako
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: Science Policy

description: We evaluated the predictivity and applicability of previously proposed models for the reproductive toxicity of chemicals to Daphnia magna [SAR QSAR Environ. Res. 27:10, 833–850] by using external data from the United States Environmental Protection Agency database ECOTOX. These models were based on quantitative structure–activity–activity relationships (QSAARs) and a quantitative activity–activity relationship (QAAR): the models can be categorized as acute-to-chronic models with (QSAAR) and without (QAAR) structural and physicochemical (e.g. distribution coefficients, log D) descriptors. We found that the QSAAR models were suitable for chemicals with an ‘–NH2 attached to aromatic carbon’ sub-structure, whereas the QAAR model was better for multicomponent compounds, coordination complexes, tin compounds and straight-chain primary amines. For chemicals with a known specific mode of action (e.g. pesticides and antibacterial agents and their derivatives), toxicity estimation within the acute-to-chronic framework requires special attention. We evaluated the applicability of the models on the basis of the descriptors in the models. We recommend that chemicals be pre-screened before their toxicities are estimated with these models: pre-screening enabled the estimation of the toxicities of some chemicals within the applicability domains of the models.
title: ADCO, Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Cart. 198-01 (11 H 1055), 185 folios, f. 0233
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2019
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 198-01 (11 H 1055), 185 folios, f. 0233, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 198-01 (11 H 1055), 185 folios, f. 0233, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Coline Enlart
Creators: name: Leibowitch, Jacques (1942-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: 1 fichier (45 pages).
description: 5 pièces jointes : Document sur le documentaire "LES ANNÉES SIDA AVEC L’AGITATEUR JACQUES LEIBOWITCH : Un film documentaire proposé par Valentin Bardawil et Caroline Petit" ; "LA LETTRE D’ICCARRE ETAT DES LIEUX ET PROJECTIONS octobre 2018" (4 versions).
Supplementary Material for: Venous Thromboembolism and the Risk of Death and Graft Loss in Kidney Transplant Recipients
Creators: name: Lam, N.N.
name: Garg, A.X.
name: Knoll, G.A.
name: Kim, S.J.
name: Lentine, K.L.
name: McArthur, E.
name: Naylor, K.L.
name: Bota, S.E.
name: Sood, M.M.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background: The implications of venous thromboembolism (VTE) for morbidity and mortality in kidney transplant recipients are not well described. Methods: We conducted a retrospective study using linked healthcare databases in Ontario, Canada to determine the risk and complications of VTE in kidney transplant recipients from 2003 to 2013. We compared the incidence rate of VTE in recipients (n = 4,343) and a matched (1:4) sample of the general population (n = 17,372). For recipients with evidence of a VTE posttransplant, we compared adverse clinical outcomes (death, graft loss) to matched (1:2) recipients without evidence of a VTE posttransplant. Results: During a median follow-up of 5.2 years, 388 (8.9%) recipients developed a VTE compared to 254 (1.5%) in the matched general population (16.3 vs. 2.4 events per 1,000 person-years; hazard ratio [HR] 7.1, 95% CI 6.0-8.4; p < 0.0001). Recipients who experienced a posttransplant VTE had a higher risk of death (28.5 vs. 11.2%; HR 4.1, 95% CI 2.9-5.8; p < 0.0001) and death-censored graft loss (13.1 vs. 7.5%; HR 2.3, 95% CI 1.4-3.6; p = 0.0006) compared to matched recipients who did not experience a posttransplant VTE. Conclusions: Kidney transplant recipients have a sevenfold higher risk of VTE compared to the general population with VTE conferring an increased risk of death and graft loss.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 1080
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1080, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1080, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
New nanobidentate Schiff base ligand of 2-aminophenol with 2-acetyl ferrocene with some lanthanide metal ions: synthesis, characterization and Hepatitis A, B, C and breast cancer docking studies
Creators: name: Walaa H. Mahmoud
name: Nessma F. Mahmoud
name: Gehad G. Mohamed
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Three lanthanide complexes (La(III), Er(III), and Yb(III)) derived from ferrocene-based Schiff base ligand (HL) were synthesized from condensation of 2-aminophenol with 2-acetylferrocene. The ligand and metal complexes were characterized based on elemental analyses, IR, 1H NMR, molar conductance, SEM and thermal analyses (TG, DTG). The molar conductance revealed that all the metal chelates were electrolytes having the general composition [M(L)(Cl)(H2O)3]Cl·4H2O. HL and its complexes were screened for their antibacterial and antifungal activity by agar diffusion method. The results of these studies showed that the metal complexes are more effective antibacterial and antifungal agents as compared with the free ligand. The anticancer activity was screened against human breast cancer cell line (MCF-7). Results indicated that metal complexes showed an increased cytotoxicity in proliferation to cell lines as compared to free ligand. Molecular docking studies were performed to identify the binding orientation or conformation of a complex in the active site of the protein. HL and its complexes were docked with crystal structure of DDB1 of breast cancer, crystal structure of HCV, RNA-dependent RNA polymerase, receptors of HBV core protein, crystal structure of the Fab fragment of anti-HAV.
[You can’t complain when in the same month your novel]
Creators: name: Margery, Arent Safir
name: Arent Safir, Margery
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Literatura argentina
Derechos humanos
Censura
"El libro de Manuel"

description: Notas: Texto sin título. "© Copyright by Margery Arent Safir 1978 – All right Reserved" especificado en la primera página. Hay además fotocopias de la primera y la última página con pasajes del texto subrayados y anotaciones manuscritas.
description: Source: Num.Ref. : JC-CAR-18.066
description: Source: Localización del archivo: Centre de Recherches Latino-Américaines (CRLA–Archivos, ITEM UMR8132). MSHS - Bât. A5, 1er étage 5 rue Théodore Lefebvre - TSA21103. 86073 Poitiers cedex 9.
History of the development of Permian to Cretaceous rifts in East Africa: a series of interpreted maps through time
Creators: name: Macgregor, Duncan
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Table of East Africa Permian Mesozoic rift basins and references
Superconducting triplet pairing in Al/Al₂O₃/Ni/Ga junctions
Creators: name: Costa, Andreas
name: Sutula, Madison
name: Lauter, Valeria
name: Song, Jia
name: Fabian, Jaroslav
name: Moodera, Jagadeesh S.
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: 530 Physik

description: Ni/Ga bilayers are a versatile playground for exploring the competition of the strongly antagonistic ferromagnetic and superconducting phases. Systematically characterizing this competition’s impact on highly ballistic Al/Al₂O₃/Ni/Ga junctions’ transport properties from both the experimental and theoretical viewpoints, we identify novel conductance peak structures, which are caused by superconducting triplet pairings at the Ni/Ga interface, and which are widely adjustable through the Ni–Ga thickness ratio. We demonstrate that these conductance anomalies persist even in the presence of an in-plane magnetic field, which provides—together with the detection of the paramagnetic Meissner effect in Ga—the clear experimental evidence that the observed conductance features serve indeed as the triplet pairings’ unique transport fingerprints. Our work demonstrates that Ni/Ga bilayers have a strong potential for superconducting spintronics applications, in particular for triplet-pairing engineering.
New nanobidentate Schiff base ligand of 2-aminophenol with 2-acetyl ferrocene with some lanthanide metal ions: Synthesis, characterization and Hepatitis A, B, C and breast cancer docking studies
Creators: name: Walaa H. Mahmoud
name: Nessma F. Mahmoud
name: Gehad G. Mohamed
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Three lanthanide complexes (La(III), Er(III) and Yb(III)) derived from ferrocene-based Schiff base ligand (HL) were synthesized from condensation of 2-aminophenol with 2-acetylferrocene. The ligand and metal complexes were characterized based on elemental analyses, IR, 1H NMR, molar conductance, SEM and thermal analyses (TG, DTG). The molar conductance revealed that all the metal chelates were electrolytes having the general composition [M(L)(Cl)(H2O)3]Cl·4H2O. HL and its complexes were screened for their antibacterial and antifungal activity by agar diffusion method. The results of these studies showed that the metal complexes are more effective antibacterial and antifungal agents as compared with the free ligand. The anticancer activity was screened against human breast cancer cell line (MCF-7). Results indicated that metal complexes showed an increased cytotoxicity in proliferation to cell lines as compared to free ligand. Molecular docking studies were performed to identify the binding orientation or conformation of a complex in the active site of the protein. HL and its complexes were docked with crystal structure of DDB1 of breast cancer, crystal structure of HCV, RNA-dependent RNA polymerase, receptors of HBV core protein, crystal structure of the Fab fragment of anti-HAV.
Online-Computation Approach to Optimal Control of Noise-Affected Nonlinear Systems with Continuous State and Control Spaces
Creators: name: Deisenroth, Marc P.
name: Weissel, Florian
name: Ohtsuka, Toshiyuki
name: Hanebeck, Uwe D.
Publisher: name: Karlsruhe
Year: 2007

description: A novel online-computation approach to optimal control of nonlinear, noise-affected systems with continuous state and control spaces is presented. In the proposed algorithm, system noise is explicitly incorporated into the control decision. This leads to superior results compared to state-of-the-art nonlinear controllers that neglect this influence. The solution of an optimal nonlinear controller for a corresponding deterministic system is employed to find a meaningful state space restriction. This restriction is obtained by means of approximate state prediction using the noisy system equation. Within this constrained state space, an optimal closed-loop solution for a finite decisionmaking horizon (prediction horizon) is determined within an adaptively restricted optimization space. Interleaving stochastic dynamic programming and value function approximation yields a solution to the considered optimal control problem. The enhanced performance of the proposed discrete-time controller is illustrated by means of a scalar example system. Nonlinear model predictive control is applied to address approximate treatment of infinite-horizon problems by the finite-horizon controller.
Toxicity and immunomodulatory efficacy of biosynthesized silver myconanosomes on pathogenic microbes and macrophage cells
Creators: name: Fatima, Faria
name: Pathak, Neelam
name: Verma, Smita Rastogi
name: Bajpai, Preeti
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Silver myconanosomes prepared from Alternaria brassicae may exhibit potential antimicrobial and immunomodulatory activity due to their inimitable character. The prepared myconanosomes were characterized by using differential light scattering, zeta potential, UV–visible spectroscopy and transmission electron microscopic analyses. Mycologically produced AgNPs were found as spherical and irregular shaped measuring size range between 55.4 and 70.23 nm. The antimicrobicidal activity of these AgNPs against pathogenic microbes was evaluated by agar well diffusion method. Results showed that AgNPs inhibit the growth of various bacteria and fungi, which may be due to the disruption of cell membranes, leakage of cytoplasm and DNA degradation. Cytotoxicity analysis of AgNPs on cell lines revealed its dose dependent effect. Moreover, significant increase of intracellular reactive oxygen species was characterized in AgNPs treated cells after 4 h of incubation. Thus, AgNPs may have a significant advantage over conventional antibiotics as microorganisms are acquiring resistance against the broad range of available antibiotics.
Geology and hydrocarbon potential of offshore SE Somalia
Creators: name: L. M. Davidson
name: T. J. Arthur
name: G. F. Smith
name: S. Tubb
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Additional seismic examples and map figures
Ethics Approval
Creators: name: Arinze, Nwadiogo Chisom
name: Emenike N. Anyaegbunam
name: Ogbonnaya, Chisom
name: Ugwu, Fabian
Publisher: name: OSF Registries
Year: 2019

description: This page contains the ethics approval for replication of Diener et al at Alex Ekwueme Federal University
A qRT-PCR method to evaluate viability of potato cyst nematode (Globodera spp.)
Creators: name: Mimee, Benjamin
name: Soufiane, Brahim
name: Dauphinais, Nathalie
name: Bélair, Guy
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Potato cyst nematodes (PCN) – Globodera rostochiensis and G. pallida – cause significant yield losses on potato worldwide. One of the main challenges to PCN management is the ability of PCN to remain dormant in the soil for several decades. For that reason, many countries have strict quarantine regulations for PCN. These regulations, although expensive and restrictive for growers, are necessary to prevent further spread of PCN but should be lifted when no more viable cysts are found. Here, we report a promising qRT-PCR method for the quantification of viable eggs and propose that this method be included in routine testing. The method was successful for quantifying G. ellingtonae, G. rostochiensis and G. pallida and was found to be very sensitive with the systematic detection of a single larva. Intron-flanking probes were used to eliminate the possibility of false positives due to genomic DNA, and an internal control was added to detect failure in PCR due to inhibitors. No amplification occurred during the testing of eggs that had previously received heat treatments or fumigation with methyl bromide. This qRT-PCR assay was used to evaluate the viability of field populations of G. rostochiensis 10 years after the establishment of a quarantine area in Saint-Amable, Quebec, Canada. The number of viable eggs after a decade of regulation was found to be very low and confirmed the effectiveness of the measures put in place. Egg viability was also monitored in microplots following five continuous years of planting resistant potatoes, and no signs of resistance-breaking genotypes were observed.
Additional file 1 of Transcriptional profiling and physiological roles of Aedes aegypti spermathecal-related genes
Creators: name: Tales Pascini
name: Ramalho-Ortigão, Marcelo
name: Ribeiro, José
name: Jacobs-Lorena, Marcelo
name: Martins, Gustavo
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 1. Tables of comparative gene expression analyses between virgin and inseminated Ae. aegypti spermathecae. Results show summaries of DEG and respective functional annotations, selected transcripts used in RNAi experiments, and phenotypic assessments.
Additional file 2 of Transcriptional profiling and physiological roles of Aedes aegypti spermathecal-related genes
Creators: name: Tales Pascini
name: Ramalho-Ortigão, Marcelo
name: Ribeiro, José
name: Jacobs-Lorena, Marcelo
name: Martins, Gustavo
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Computational Biology

description: Additional file 2. Expression profiles and fitness effects from knockdown of selected transcripts including survival, oviposition rates, fecundity, and morphological effect on Ae. aegypti female ovaries.