cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The AGB bump: a calibrator for the core mixing
Creators: name: Bossini, Diego
name: Miglio, Andrea
name: Salaris, Maurizio
name: Girardi, Léo
name: Montalbán, Josefina
name: Bressan, Alessandro
name: Marigo, Paola
name: Noels, Arlette
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The efficiency of convection in stars affects many aspects of their evolution and remains one of the key-open questions in stellar modelling. In particular, the size of the mixed core in core-He-burning low-mass stars is still uncertain and impacts the lifetime of this evolutionary phase and, e.g., the C/O profile in white dwarfs. One of the known observables related to the Horizontal Branch (HB) and Asymptotic Giant Branch (AGB) evolution is the AGB bump. Its luminosity depends on the position in mass of the helium-burning shell at its first ignition, that is affected by the extension of the central mixed region. In this preliminary work we show how various assumptions on near-core mixing and on the thermal stratification in the overshooting region affect the luminosity of the AGB bump, as well as the period spacing of gravity modes in core-He-burning models.
description: Submitted to EPJ Web of Conferences, to appear in the Proceedings of the 3rd CoRoT Symposium, Kepler KASC7 joint meeting; 2 pages, 2 figures
Integrability, intertwiners and non-linear algebras in Calogero models
Creators: name: Carrillo-Morales, Francisca
name: Correa, Francisco
name: Lechtenfeld, Olaf
Publisher: name: Berlin ; Heidelberg : Springer
Year: 2021
Subjects: subject: Conformal and W Symmetry
subject: Discrete Symmetries
subject: Integrable Field Theories
subject: Integrable Hierarchies
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: For the rational quantum Calogero systems of type A1⊕A2, AD3 and BC3, we explicitly present complete sets of independent conserved charges and their nonlinear algebras. Using intertwining (or shift) operators, we include the extra ‘odd’ charges appearing for integral couplings. Formulæ for the energy eigenstates are used to tabulate the low-level wave functions.
Mutig sein – den Kindern eine Stimme geben! Eine empirische Studie zur Lehrer-Schüler-Beziehung aus der Perspektive der Kindergartenkinder
Creators: name: Infante, Natascha
name: Läubli-Haeny, Martina
Publisher: name: Zenodo
Year: 2021
Subjects: Schule
Kindergarten
Unterricht
Lehrer-Schüler-Beziehung
Beziehungsarbeit
Lernmotivation
Entwicklungspsychologie
Vertrauen
empirische Studie
Innovationspreis
Stiftung Pestalozzianum

description: Die Lehrer-Schüler-Beziehung1 ist im heutigen Schulalltag von grosser Bedeutung. Die Grundhaltung gegenüber dem Kind stellt eine wichtige Basis in der Auseinandersetzung mit der Lehrer-Schüler-Beziehung dar. Einerseits beeinflusst sie die persönliche Entwicklung, andererseits wirkt sie auf die Lernleistung der Schülerinnen und Schüler. Ebenso trägt sie zur Arbeitszufriedenheit der Lehrperson bei. Aus der erarbeiteten Theorie und der Datenanalyse werden fünf Qualitätsdimensionen ersichtlich, die als Bedingungen der Lehrer-Schüler- Beziehung stehen. Es wird der Frage nachgegangen, wie sich diese Dimensionen aus der Perspektive der Kindergartenkinder auf die Lehrer-Schüler-Beziehung auswirken. Zur Grundlage der Bearbeitung der Fragestellung wird aktuelle Fachliteratur beigezogen. Mithilfe des Bilderbuchs «Mutig, Mutig» von Lorenz Pauli und Kathrin Schärer sowie einem für die Masterarbeit selbst entwickelten Spiel für die Kindergartenkinder mit dem Titel «Mutig sein – den Kindern eine Stimme geben!» wurden die qualitativen Leitfadeninterviews mit 28 Kindergartenkindern durchgeführt. Die Daten werden mithilfe der qualitativen Inhaltsanalyse gesichtet, codiert und interpretiert. Die Ergebnisse zeigen, dass alle fünf Qualitätsdimensionen von den Kindern genannt werden. Die Qualitätsdimension «Vertrauen» wird von den Kindergartenkindern am meisten genannt. Die Kinder nehmen die Lehrperson als verlässlich, unterstützend und anerkennend wahr.
description: +repphzhbib2021MA
Generalized Langevin Equation with Hydrodynamic Backflow: Equilibrium Properties
Creators: name: Fodor, Étienne
name: Grebenkov, Denis S.
name: Visco, Paolo
name: van Wijland, Frédéric
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We review equilibrium properties for the dynamics of a single particle evolving in a visco--elastic medium under the effect of hydrodynamic backflow which includes added mass and Basset force. Arbitrary equilibrium forces acting upon the particle are also included. We discuss the derivation of the explicit expression for the thermal noise correlation function that is consistent with the fluctuation-dissipation theorem. We rely on general time-reversal arguments that apply irrespective of the external potential acting on the particle, but also allow one to retrieve existing results derived for free particles and particles in a harmonic trap. Some consequences for the analysis and interpretation of single-particle tracking experiments are briefly discussed.
Anomalous phonon behavior of carbon nanotubes: First-order influence of external load
Creators: name: Aghaei, Amin
name: Dayal, Kaushik
name: Elliot, Ryan S.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90799 Environmental Engineering not elsewhere classified
subject: FOS: Environmental engineering
subject: 90599 Civil Engineering not elsewhere classified
subject: FOS: Civil engineering

description: External loads typically have an indirect influence on phonon curves, i.e., they influence thephonon curves by changing the state about which linearization is performed. In this paper, we show that in nanotubes, the axial load has a direct first-order influence on the long-wavelength behavior of the transverse acoustic (TA) mode. In particular, when the tube is force-free, the TA mode frequencies vary quadratically with wave number and have curvature (second derivative) proportional to the square-root of the nanotube's bending stiffness. When the tube has non-zero external force, the TA mode frequencies vary linearly with wave number and have slope proportional to the square-root of the axial force. Therefore, the TA phonon curves—and associated transport properties—are not material properties but rather can be directly tuned by external loads. In addition, we show that the out-of-plane shear deformation does not contribute to this mode and the unusual properties of the TA mode are exclusively due to bending. Our calculations consist of 3 parts: First, we use a linear chain of atoms as an illustrative example that can be solved in close-form; second, we use our recently developed symmetry-adaptedphonon analysis method to present direct numerical evidence; and finally, we present a simple mechanical model that captures the essential physics of the geometric nonlinearity in slendernanotubes that couples the axial load directly to the phonon curves. We also compute thedensity of states and show the significant effect of the external load.
Glacier and ice sheet flow
Creators: name: Fowler, Andrew
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 49
subject: Mathematical sciences

description: This review of the dynamics of the flow of glaciers and ice sheets focusses on the mathematical models which have been developed to explain a number of observations in the behaviour of these large ice masses. It takes a personal view, starting with an account of the historical development of the subject, followed by a tour of some of the observational puzzles and theoretical solutions which I have found most intriguing. Most of the discourse involves basal processes: glacier sliding, subglacial hydrology, bedform generation. I describe in some detail wave ogives, surging glaciers, subglacial floods and subglacial bedforms. I variously explore issues in sliding theory: sub-temperate sliding, slip or till deformation; the rheology of till; the status of the instability theory of drumlin formation. And in an effort to broaden the field of view, I include discussion of Dansgaard-Oeschger and Heinrich events, grounding line stability, and the formation of eskers and, particularly, flutes.
Raízes de um cristianismo exacerbado
Creators: name: Manuel Pereira, Henrique
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2017

description: Resumo Guerra Junqueiro (1850-1923) ocupa lugar de relevo na visibilidade expressiva e sintomática do fenómeno anticlerical português, tendo o seu anticlericalismo expressão particularmente violenta em A Velhice do Padre Eterno (1885), com manifesto prolongamento em Pátria (1896), a ponto de ambas as obras terem sido apontadas como “o evangelho do anticlericalismo em Portugal”. Todavia, a visibilidade do anticlericalismo junqueiriano precede em muitos anos aquela primeira obra. O presente artigo ocupa-se, pois, das raízes do anticlericalismo de Junqueiro. Para o efeito, cruzando argumentos e “demolindo adquiridos”, persegue em particular a composição poética “O Cura da minha aldeia”, ainda não devidamente historiada e inscrita na Obras de Guerra Junqueiro (Poesia). Palavras-Chave: Guerra Junqueiro, Anticlericalismo, A Velhice do Padre Eterno, O Peregrino, Obras Completas. Abstract Guerra Junqueiro (1850-1923) occupies a prominent place in the expressive and symptomatic visibility of the Portuguese anticlerical phenomenon, his anticlericalism having a particularly violent expression in A Velhice do Padre Eterno (1885), with a manifest extension in Pátria (1896), having both works pointed out as “the gospel of anticlericalism in Portugal”. However, the visibility of Junqueira's anticlericalism precedes that first work in many years. Hence, the present article is concerned with the roots of Junqueiro's anticlericalism. To this end, crossing arguments and “demolished the previous acquired”, he particularly pursues the poetical composition “O Cura da minha aldeia”, not yet properly recorded and inscribed in Obras de Guerra Junqueiro (Poetry). Keywords: Guerra Junqueiro, Anticlericalism, The Old Age of the Eternal Father, The Pilgrim, Complete work
description: Revista Lusófona de Ciência das Religiões, v. 1 n. 20 (2017): «O anticlericalismo e os desafios da contemporaneidade ao Cristianismo»
Semantic and episodic memory in adults with temporal lobe epilepsy
Creators: name: Jones, Sarah Barrett
name: Miller, Laurie A.
name: Kleitman, Sabina
name: Nikpour, Armin
name: Lah, Suncica
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The primary aims were to (1) identify the factor structure of tests thought to measure semantic and episodic memory and (2) examine whether patterns of impairment would show a double dissociation between these two memory systems at an individual level in patients with temporal lobe epilepsy (TLE). The secondary aim was to explore the impact of epilepsy-related variables on performance. This retrospective study involved a cohort of 54 adults who had been diagnosed with TLE and had undergone a neuropsychological assessment that included four memory tests traditionally used to measure either semantic memory (picture naming, animal fluency) or episodic memory (story recall, word list recall) at a single epilepsy surgery center in Australia. Principal component analysis revealed two factors albeit with unexpected loadings. Picture naming and story recall loaded on one factor. Animal fluency and word list recall loaded on another factor. There was no evidence of a double dissociation between semantic and episodic memory at an individual level. Left hemisphere seizure focus and early age of seizure onset related to worse performance on word list recall, picture naming and animal fluency, respectively. Our study highlights the importance of caution when interpreting the results of neuropsychological assessments, as not all putative tests of semantic and episodic memory may necessarily be measuring the same construct. Future directions for research are also considered.
The formation and disintegration of magnetic bright points observed by Sunrise/IMaX
Creators: name: Utz, D.
name: Iniesta, J. C. del Toro
name: Rubio, L. R. Bellot
name: Jurčák, J.
name: Pillet, V. Martínez
name: Solanki, S. K.
name: Schmidt, W.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The evolution of the physical parameters of magnetic bright points (MBPs) located in the quiet Sun (mainly in the interwork) during their lifetime is studied. First we concentrate on the detailed description of the magnetic field evolution of three MBPs. This reveals that individual features follow different, generally complex, and rather dynamic scenarios of evolution. Next we apply statistical methods on roughly 200 observed MBP evolutionary tracks. MBPs are found to be formed by the strengthening of an equipartition field patch, which initially exhibits a moderate downflow. During the evolution, strong downdrafts with an average velocity of 2.4 km/s set in. These flows, taken together with the concurrent strengthening of the field, suggest that we are witnessing the occurrence of convective collapses in these features, although only 30% of them reach kG field strengths. This fraction might turn out to be larger when the new 4 m class solar telescopes are operational as observations of MBPs with current state of the art instrumentation could still be suffering from resolution limitations. Finally, when the bright point disappears (although the magnetic field often continues to exist) the magnetic field strength has dropped to the equipartition level and is generally somewhat weaker than at the beginning of the MBP's evolution. Noteworthy is that in about 10% of the cases we observe in the vicinity of the downflows small-scale strong (exceeding 2 km/s) intergranular upflows related spatially and temporally to these downflows.
description: 19 pages, 13 figures; final version published in "The Astrophysical Journal"
Projecting Hydro-Morphodynamic Impacts of Planned Layout Changes for a Coastal Harbor
Creators: name: Lojek, Oliver
name: Goseberg, Nils
name: Schlurmann, Torsten
Publisher: name: New York, NY : Soc.
Year: 2021
Subjects: subject: Germany
subject: North Sea Coast [Germany]
subject: Boats
subject: Depth profiling
subject: Doppler effect
subject: Dewey Decimal Classification::600 | Technik::690 | Hausbau, Bauhandwerk
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie::380 | Handel, Kommunikation, Verkehr

description: The macrotidally influenced harbor of Dagebüll on the North Sea coast of Germany features a piled south jetty, for which provided constructive designs are investigated regarding their potential hydro-morphological impacts on the harbor area and adjacent navigational channel. The harbor experiences a steady accumulation of sediment. This results in a reduction of navigational depth and necessitates regular maintenance dredging constituting a cost aspect. A comprehensive field study was conducted, deploying a ridged inflatable boat (RIB) equipped with differential Global Positioning System, a winch for conductivity, temperature, and depth casting as well as sediment and water sampling and an acoustic Doppler current profiler for current profiling. Measurements reveal a tidally governed alternating flow pattern inducing a vortex current inside the harbor basin. Hydrodynamic sea floor grain sorting is detected through sediment sampling. A numerical model cascade is developed and calibrated against available tide gauge and sediment inventory data as well as multibeam survey data and acquired field measurements. The calibrated model cascade is used to simulate layout variants and compare resulting impacts to identify preferable jetty designs.
Symmetry protection of critical phases and global anomaly in $1+1$ dimensions
Creators: name: Furuya, Shunsuke C.
name: Oshikawa, Masaki
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We derive a selection rule among the $(1+1)$-dimensional SU(2) Wess-Zumino-Witten theories, based on the global anomaly of the discrete $\mathbb{Z}_2$ symmetry found by Gepner and Witten. In the presence of both the SU(2) and $\mathbb{Z}_2$ symmetries, a renormalization-group flow is possible between level-$k$ and level-$k'$ Wess-Zumino-Witten theories only if $k\equiv k' \mod{2}$. This classifies the Lorentz-invariant, SU(2)-symmetric critical behavior into two "symmetry-protected" categories corresponding to even and odd levels,restricting possible gapless critical behavior of translation-invariant quantum spin chains.
Design thinking for patient safety: Protocol of a scoping review
Creators: name: Sichieri, Karina
name: Quintana, Luis Del Valle
name: Secoli, Silvia
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Nursing
subject: FOS: Health sciences
subject: Public Health
subject: Medical Education
subject: Medicine and Health Sciences
subject: design thinking
subject: human centered design
subject: patient safety
subject: safety goals

description: Scoping review that seeks to know the current state of the use of the design thinking methodology to promote patient safety in health services.
Risks associated with chlorination
Creators: name: Walker, Bryan H.
name: Nolette  Conway-Schemp
name: Krofchik, Mark
name: Carnegie Mellon University.Engineering Design Research Center.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90799 Environmental Engineering not elsewhere classified
subject: FOS: Environmental engineering
subject: 90599 Civil Engineering not elsewhere classified
subject: FOS: Civil engineering

description: Abstract: "This paper examines the risks of using and not using chlorine chemicals in the water disinfection process. Water disinfection has been termed by some as the most significant public health measure of this century. When the consideration of eliminating chlorine completely surfaces, one must take a step back and try to understand more completely the risks of such a decision. This paper presents the risks associated with chlorination and its by-products. This paper also discusses with [sic] the results of not chlorinating and presents several actual consequences experienced by several countries."
АЛЛОМАГА НАВОИЙ ТАЪРИФИ
Creators: name: Мавлянов, Умид
Publisher: name: Zenodo
Year: 2025

description: Мазкур мақолада Ҳиротда темурйлар даврида шаклланган ўзига хос академия – Бойсунғур Санъат академиясининг кенжа вакилларидан бўлган Фахруддин Али Сафийнинг ҳаёти ва мероси тадқиқ этилган. Мутафаккирнинг ўзига хос джунёқараши ва меросининг аҳамиятли томонларидан бири сифатид “Мажолис ун-нафоис”да Алишер Навоий ўзидан 22 ёш кичик замондоши Али Сафийга махсус ўрин ажратиб, унга алоҳғида эҳтиром билан таърифлар келтиргани таъкидланган.
A Resonant One-Step 325 v to 3.3-10 v DC-DC Converter with Integrated Power Stage Benefiting from High-Voltage Loss-Reduction Techniques
Creators: name: Rindfleisch, Christoph
name: Wicht, Bernhard
Publisher: name: New York, NY : IEEE
Year: 2021
Subjects: subject: DC-dc converter
subject: high power density
subject: high voltage (HV)
subject: HV loss reduction
subject: lateral insulated gate bipolar transistor (IGBT)
subject: light-load efficient
subject: silicon-on-insulator (SOI)
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: This work presents a self-timed resonant high-voltage (HV) dc-dc converter in HV CMOS silicon-on-insulator (SOI) with a one-step conversion from 100-325 V input down to a 3.3-10 V output, optimized for applications below 500 mW, such as IoT, smart home, and e-mobility. Unlike bulky power modules, the HV converter is fully integrated, including an on-chip power stage, with only one external inductor (10 $\mu \text{H}$ ) and capacitor (470 nF). It reaches a high power density of 752 mW/cm3, an overall peak efficiency as high as 81%, and a light-load efficiency of 73.2% at 5 V and 50 mW output. HV loss-reduction techniques are presented and experimentally confirmed to offer an efficiency improvement of more than 32%. Integrated HV insulated gate bipolar transistors (IGBTs) are discussed and implemented as an attractive alternative to conventional integrated HV power switches, resulting in 20% smaller area at lower losses.
Usos Etnográficos Do Discurso Catequético
Creators: name: Correia De Melo, Paulo
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2017

description: Resumo A ideia principal deste texto é apontar alguns usos (quiçá abusos) do discurso religioso normativo (mandamentos – da Lei de Deus e da Igreja -, sacramentos, orações, obras de misericórdia…) em ambiente etnográfico, seja por deslocamento, por derivação, por fuga, por analogia, por burla, por recriação, por recreação… Privilegiaremos as quadras como corpus de referência, embora possamos recorrer a outras expressões. Palavras-Chave: tradição; etnografia; quadra; catecismo; apoclericalismo Abstract The main idea of this text is to point out a few uses (perhaps abuses) of normative religious discourse (the ten commandments, the church’s commandments, sacraments, prayers, works of mercy…) in an ethnographic environment, whether by displacement, by deriving, by escape, by analogy, by deception, by recreation, by recreating, by enjoyment... We will prioritize the four-line stanza as reference corpus, although we may use other traditional phrases. Keywords: tradition, ethnography, four-line stanza, catechism, apoclericalism
description: Revista Lusófona de Ciência das Religiões, v. 1 n. 20 (2017): «O anticlericalismo e os desafios da contemporaneidade ao Cristianismo»
Structural design by hierarchical decomposition
Creators: name: Maher, Mary Lou.
name: Carnegie Mellon University.Engineering Design Research Center.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90799 Environmental Engineering not elsewhere classified
subject: FOS: Environmental engineering
subject: 90599 Civil Engineering not elsewhere classified
subject: FOS: Civil engineering

description: Abstract: "Design by decomposition is a common approach to complex design problems. Ideally, decomposition results in loosely coupled subsystems and a reduction of the complexity of the overall problem. Design by decomposition also involves recomposition when the subproblem solutions are combined to form a larger system. An experienced designer is able to recognize appropriate decompositions as well as the implications of recomposition better than a novice designer, implying that the knowledge based expert system techniques may facilitate the representation of this knowledge within a computer program. EDESYN is an expert system shell that facilitates the development of a design expert system incorporating the design by decomposition strategy.The experienced designer builds a knowledge base that includes both decomposition and recomposition knowledge. The decomposition knowledge includes a hierarchy of subsystems and planning rules to adapt the hierarchy for a specific problem. The recomposition knowledge includes constraints on the composition of subsystems. Two structural design expert systems have been developed using EDESYN: STRYPES and STANLAY. STRYPES synthesizes alternative structural configurations for a given high rise building using subsystems such as frames, walls, slabs, and grids. STANLAY generates alternative layouts for the structural system in a given floor plan and approximates the load and size specifications for the components of the system."
Examples of non-trivial contact mapping classes in all dimensions
Creators: name: Massot, Patrick
name: Niederkrüger, Klaus
Publisher: name: arXiv
Year: 2015
Subjects: subject: Symplectic Geometry (math.SG)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 57R17 (Primary) 53D10, 32Q65, 57R52, 53D12 (Secondary)

description: We give examples of contactomorphisms in every dimension that are smoothly isotopic to the identity but that are not contact isotopic to the identity. In fact, we prove the stronger statement that they are not even symplectically pseudo-isotopic to the identity. We also give examples of pairs of contactomorphisms which are smoothly conjugate to each other but not by contactomorphisms.
description: 14 pages, 1 figure v2: Made some exposition improvements, corrected a mistake pointed out by Sylvain Courte in the proof of Observation 2.1. To appear in IMRN
Computer modelling and simulation in clinics: mapping usage and opinions for advancing in silico medicine
Creators: name: Lesage, Raphaelle
name: Van Oudheusden, Michiel
name: Contin, Martina
name: Schievano, Silvia
name: Geris, Liesbet
name: Capelli, Claudio
Publisher: name: Zenodo
Year: 2022

description: Accepted abstract for oral presentation at the VPH2022 conference in Porto. The study reports the results of an online survey towards the clinical community about their use and perception of computational modelling and simulation tools (see abstract).
Dealing with separation or near-to-separation in the model for multinomial response with application to childhood health seeking behavior data from a complex survey
Creators: name: Nusrat, Nowrin
name: Rahman, M. S.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Separation or monotone-likelihood can be observed in fitting process of a multinomial logistic model using maximum likelihood estimation (MLE) when sample size is small and/or one of the outcome categories is rare and/or there is one or more influential covariates, resulting in infinite or biased estimate of at least one regression coefficient of the model. This study investigated empirically to identify the optimal data condition to define both ‘separation’ and ‘near-to-separation’ (partial separation) and explored their consequences in MLE and provided a solution by applying a penalized likelihood approach, which has been proposed in the literature, by adding a Jeffreys prior-based penalty term to the original likelihood function to remove the first-order bias in the MLEs of the multinomial logit model via equivalent Poisson regression. Furthermore, the penalized estimating equation (PMLE) is extended to a weighted estimating equation allowing for survey-weight for analyzing data from a complex survey. The simulation study suggests that the PMLE outperforms the MLE by providing smaller amount of bias and mean squared of error and better coverage. The methods are applied to analyze data on choice of health facility for treatment of childhood diseases.
PLASMEPSIN V INHIBITION AS A NEW POTENTIAL ANTIMALARIAL STRATEGY
Creators: name: GAMBINI, LUCA
Publisher: name: Universit� degli Studi di Milano
Year: 2014

description: Natural products have always played an important role in the drug discovery process. Plants, in particular, have formed the basis of a sophisticate traditional medicine system, and in many way they still provide inspiration and pharmacological inputs for the development of new active compounds. The history of malaria treatment is probably the best example of natural products importance in drug discovery: Quinine, the first therapeutic agent used against malaria, was isolated from the bark of Cinchona spp. in 1820, and its synthetic analogues were used until drug-resistance issues required new therapeutic agents to be developed. The answer to this problem was found in another plant, Artemisia annua, used in the treatment of fevers in Traditional Chinese Medicine (TCM). Artemisinin was extracted and characterized as a lead compound, and artemisinin analogues are now used for treatment of malaria in many countries, as part of artemisinin-combination therapies (ACTs). Unfortunately, after few years, an increasing number of Plasmodium falciparum strains started to develop resistance against these compounds. New therapeutic agents are needed to provide effective way to deal with resistant strain, and natural products could be used once again as a source of new chemical entities with antimalarial properties. While isolation and characterization of new natural products still play an important role in drug discovery, new strategies need to be investigated in order to speed up the process that lead from a natural extract with interesting pharmacological properties to a potential natural product lead compound in order to overcome chemistry and environmental issues. In this work, a new methodology to exploit natural products active compounds is presented. A common structure found in numerous natural products extracted from various biological sources is used as a starting point to create a small library to compounds that retain the biological activity of the starting product. The same strategy was then used to synthesize a new antimalarial compound combining a natural product scaffold with the information derived from an intensive SAR study on Plasmepsin V peptidomimetic inhibitors. This molecule, active against both chloroquine-resistant and choloroquine-sensitive P.f strains, may be used as a starting point for a new class of compound with potential PMV inhibition.
A Geração de 70 e o Anticlericalismo
Creators: name: Augusto Nery, António
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2017

description: Resumo A temática religiosa, quase sempre com uma característica anticlerical, é uma constante na Literatura Portuguesa, desde o período medieval até a contemporaneidade. Neste trabalho espero traçar algumas reflexões sobre o anticlericalismo nessa literatura e como ele se configura nas obras de alguns de seus autores. Buscarei, por intermédio de uma contextualização histórica, analisar preliminarmente de que forma os autores de diversos períodos dialogavam com a Igreja e seus representantes, o clero. Darei ênfase à maneira pela qual a Geração de 70, grupo intelectual da segunda metade do século XIX, lidou com a crítica anticlerical, uma vez que, para esses intelectuais, a Igreja Católica constituía-se um dos fatores que teriam levado Portugal à situação decadente, que eles pretendiam denunciar e criticar. Palavras-Chave: Literatura Portuguesa; Anticlericalismo; Geração de 70; Século XIX; Igreja Católica. Abstract The religious theme, almost always carries an anticlerical feature, finds a common ground in the Portuguese Literature, from the medieval period to the contemporaneity. In this work I hope to share some thoughts upon the anticlericalism in this literature and how it is shown in the works of their authors. I will analyse preliminarily through a historical contextualization the way the authors from several periods dialogued with the Church and its representatives, the Clergy. Enphasis will be given on the way in which the seventies Generation, intellectual group from the second half of the nineteenth century, dealt with the anticlerical criticism. The Catholic Church,for these intellectuals, represented one of the factors which led Portugal to a declining situation , a fact they intended to denounce and criticize. Keywords: Portuguese Literature; Anticlericalism; The seventies Generation; Nineteenth century; Catholic Church.
description: Revista Lusófona de Ciência das Religiões, v. 1 n. 20 (2017): «O anticlericalismo e os desafios da contemporaneidade ao Cristianismo»
Neuropsychological functioning in dysgenesis of the corpus callosum with colpocephaly
Creators: name: Kosky, Karen M.
name: Phenis, Richard
name: Kiselica, Andrew M.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Dysgenesis of the corpus callosum is a rare developmental abnormality in brain structure that is associated with changes in physical appearance, as well as behavioral and cognitive consequences. A relatively commonly co-occurring structural abnormality with callosal dysgenesis is colpocephaly, characterized by enlargement of the posterior lateral ventricles and reductions in posterior brain volume. Although some case studies of individuals with this combination of structural malformations exist, they do not often report results of neuropsychological evaluation. Furthermore, those that do contain neuropsychological data may be of limited generalizability due to unique patient characteristics. The current manuscript overcomes these limitations by presenting the case of a 55-year-old male with callosal dysgenesis and colpocephaly identified in adulthood. The paper includes a full profile of his performance on a comprehensive neuropsychological test battery with discussion of differential diagnosis and treatment planning. Findings indicated low average intellectual abilities with deficits in processing speed, executive functions, and social cognition, consistent with expectations based on callosal dysgenesis. One surprising finding was that despite the significant posterior involvement of colpocephaly, visuospatial skills were a relative strength. The manuscript provides a clear characterization of callosal dysgenesis with colpocephaly to facilitate future clinical comparisons and set the stage for future research on this rare neuromorphological presentation.
Free Collisions in a Microgravity Many-Particle Experiment. IV. - Three-Dimensional Analysis of Collision Properties
Creators: name: Weidling, René
name: Blum, Jürgen
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The bouncing barrier, a parameter combination at which dust particles in the protoplanetary disk always rebound in mutual collisions, is one of the crucial steps of planet formation. In the past years, several experiments have been performed to determine the mass and velocity regimes at which perfect bouncing does occur and those where there is a chance of the aggregates sticking together. We conducted a microgravity experiment, which allows us to investigate free collisions of millimeter-sized SiO2 dust aggregates at the relevant velocities. We analyzed 52 collisions in detail with velocities of 3.4 mm/s to 6.2 cm/s and found four of them leading to sticking, while the other aggregates rebounded. Three out of the four sticking collisions occurred at velocities where previously only bouncing had been predicted. Although the probability for sticking is low, this opens a new possibility for growth beyond millimeter sizes. Our setup allowed us to obtain the complete three-dimensional collision information. Since most previous experiments were interpreted based on two-dimensional information, we compare our three-dimensional values with those obtained if only one projection had been available. We find that the error of a two-dimensional analysis of the collision velocity is very small. The distribution of the coefficient of restitution in the two-dimensional view is representative of the real case, but for any given collision its value can be far off. Impact parameters always have to be analyzed three-dimensionally, because the two-dimensional values are not meaningful in any way.
description: accepted by Icarus
The 2023 Belgian clinical guidance on anticoagulation management in hospitalized and ambulatory COVID-19 patients
Creators: name: Vanassche, Thomas
name: Engelen, Matthias M
name: Orlando, Christelle
name: Vandenbosch, Kristel
name: Gadisseur, Alain
name: Hermans, Cedric
name: Jochmans, Kristin
name: Minon, Jean-Marc
name: Motte, Serge
name: Peperstraete, Harlinde
name: Péters, Pierre
name: Sprynger, Muriel
name: Lancellotti, Patrizio
name: Dehaene, Isabelle
name: Emonts, Patrick
name: Vandenbriele, Christophe
name: Verhamme, Peter
name: Oury, Cecile
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: COVID-19 is associated with an increased risk for thrombotic complications. The trials investigating the optimal thromboprophylactic dose are performed in challenging times and seemingly produce conflicting evidence. The burdensome circumstances, divergent endpoints, and different analytical approaches hamper comparison and extrapolation of available evidence. Most importantly, clinicians should provide thromboprophylaxis in hospitalized COVID-19 patients while (re)assessing bleeding and thrombotic risk frequently. The COVID-19 Thromboprophylaxis Working Group of the BSTH updated its guidance document. It aims to summarize the available evidence critically and to guide clinicians in providing the best possible thromboprophylaxis.
Regression models using the LINEX loss to predict lower bounds for the number of points for approximating planar contour shapes
Creators: name: Jayasinghe, J. M. Thilini
name: Ellingson, Leif
name: Prematilake, Chalani
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Neuroscience
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Researchers in statistical shape analysis often analyze outlines of objects. Even though these contours are infinite-dimensional in theory, they must be discretized in practice. When discretizing, it is important to reduce the number of sampling points considerably to reduce computational costs, but to not use too few points so as to result in too much approximation error. Unfortunately, determining the minimum number of points needed to achieve sufficiently approximate the contours is computationally expensive. In this paper, we fit regression models to predict these lower bounds using characteristics of the contours that are computationally cheap as predictor variables. However, least squares regression is inadequate for this task because it treats overestimation and underestimation equally, but underestimation of lower bounds is far more serious. Instead, to fit the models, we use the LINEX loss function, which allows us to penalize underestimation at an exponential rate while penalizing overestimation only linearly. We present a novel approach to select the shape parameter of the loss function and tools for analyzing how well the model fits the data. Through validation methods, we show that the LINEX models work well for reducing the underestimation for the lower bounds.
Acceleration of cyclic steady state convergence for pressure swing adsorption models
Creators: name: Smith, Oliver J.
name: Westerberg, Arthur W.
name: Carnegie Mellon University.Engineering Design Research Center.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: Abstract: "A new solution algorithm is presented that accelerates the convergence of pressure swing adsorption dynamic models. The algorithm combines the desirable properties of Quasi-Newton and successive substitution methods to obtain a significant acceleration factor."
Three solutions for a Neumann partial differential inclusion via nonsmooth Morse theory
Creators: name: Colasuonno, Francesca
name: Iannizzotto, Antonio
name: Mugnai, Dimitri
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We study a partial differential inclusion, driven by the p-Laplacian operator, involving a p-superlinear nonsmooth potential, and subject to Neumann boundary conditions. By means of nonsmooth critical point theory, we prove the existence of at least two constant sign solutions (one positive, the other negative). Then, by applying the nonsmooth Morse relation, we find a third non-zero solution.
Barriers and facilitators for physical activity on acute geriatric and rehabilitation wards: a survey study
Creators: name: Mols, Ine
name: van Dijk, Margreet
name: De Roo, Maaike L.
name: Tournoy, Jos
name: Van Grootven, Bastiaan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Science Policy
Biological Sciences not elsewhere classified
Computational Biology

description: During hospitalisation, physical inactivity is common among older patients and is associated with adverse outcomes, e.g. functional decline. This study identified barriers and facilitators of physical activity with geriatric patients during hospital admission. This is a cross-sectional descriptive study, on two acute geriatric units and one rehabilitation unit, using a researcher-administered survey methodology in patients 70 years or older. A new questionnaire was developed based on a literature review, and was administered bedside and face-to-face with the older patients. 72 patients, mean age 83.6 years, completed the questionnaire. 88.9% of the participants found physical activity important during hospitalisation. The main patient-related determinants were fear of falling and symptoms of current illness (e.g. pain). The main environmental-related determinants were the presence of medical devices, and the availability of walking aids. Half of the patients felt motivated by the hospital staff, and one out of six participants felt discouraged. Receiving more assistance for walking and having access to other types of physical activity was expected to increase physical activity. Additionally, motivation from family would be a facilitator for 44.4% of the participants. Promoting physical activity on acute geriatric units will require interventions at different levels. Most importantly, focusing on interpersonal motivators and positive reinforcement by hospital staff could be beneficial strategies to increase the physical activity of older hospitalised patients.
Studies of traversable wormholes and holography
Creators: name: Waki Misobuchi, Anderson Seigo
name: 0000-0002-6191-4899
Publisher: name: The University of Texas at Austin
Year: 2022
Subjects: Holographic duality
AdS/CFT correspondence
Traversable wormholes

description: This dissertation is based on studies of traversable wormholes within the context of the holographic duality. First, we study the traversability obtained via the introduction of a direct coupling between the two asymptotic boundaries of a non-traversable wormhole and we construct a traversable wormhole with angular momentum. We discuss its dual interpretation and the implications to the information transfer. Second, we study the relation between the Sachdev-Ye-Kitaev (SYK) model and an eternal traversable wormhole with global a AdS₂ geometry. We consider a sparse version of the SYK model defined via a regular hypergraph and we numerically simulate a system of two copies of the sparse SYK coupled by a bilinear interaction. We discuss the finite-size effects in this system and obtain the optimal level of sparseness that preserves features of the original SYK model such that it can still be holographically interpreted as a traversable wormhole.
Melting temperature of heavy quarkonium with a holographic potential up to sub-leading order
Creators: name: Zhang, Zi-qiang
name: Wu, Yan
name: Hou, De-fu
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A calculation of the melting temperatures of heavy quarkonium states with the holographic potential was introduced in a previous work. In this paper, we consider the holographic potential at sub-leading order, which permits finite coupling corrections to be taken into account. It is found that this correction lowers the dissociation temperatures of heavy quarkonium.
description: 4 pages, 1 figure
Supplemental Material for "Security Assurance Cases in the Medical Domain: A Case Study"
Creators: name: Andersson, Adam
name: Fransson, Max
name: Mohamad, Mazen
name: Steghöfer, Jan-Philipp
Publisher: name: Zenodo
Year: 2023

description: This additional online material supplements the manuscript "Security Assurance Cases in the Medical Domain: A Case Study" considered for submission at IFIPSEC 2023. It contains the following information: Security Assurance Cases – Example Questionnaire for Maintainability Focus Group Overview of Relevant Roles at the Case Company Use Cases of CASCADE in the Medical Domain Overlap of CASCADE with Existing Regulation
NETSYN : neural networks for acquisition and use of synthesis knowledge
Creators: name: Garrett, James Henry.
name: Ivezic, Nenad
name: Carnegie Mellon University.Engineering Design Research Center.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90799 Environmental Engineering not elsewhere classified
subject: FOS: Environmental engineering
subject: 90599 Civil Engineering not elsewhere classified
subject: FOS: Civil engineering

description: technical report
An approach for knowledge acquisition from a survey data by conducting Bayesian network modeling, adopting the robust coplot method
Creators: name: Ersel, Derya
name: Atılgan, Yasemin Kayhan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: This study proposes a methodological approach for extracting useful knowledge from survey data by performing Bayesian network (BN) modeling and adopting the robust coplot analysis results as prior knowledge about association patterns hidden in the data. By addressing the issue of BN construction when the expert knowledge is limited/not available, this proposed approach facilitates the modeling of large data sets describing numerously observed and latent variables. By answering the question of which node(s)/link(s) should be retained or discarded from a BN, we aim to determine a compact model of variables while considering the desired properties of data. The proposed method steps are explained on real data extracted from Turkey Demographic and Health Survey. First, a BN structure is created, which is based solely on the judgment of the analyst. Then the coplot results are employed to update the BN structure and the model parameters are updated using the updated structure and data. Loss scores of the BNs are used to ensure the success of the updated BN that inherits knowledge from coplot.