cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Wikipedia and AI: Access, representation, and advocacy in the age of large language models
Creators: name: McDowell, Zachary
Publisher: name: University of Illinois at Chicago
Year: 2024
Subjects: classificationCode: 3605
subject: Screen and digital media
classificationCode: 3506
subject: Marketing
subject: FOS: Economics and business
classificationCode: 36
subject: Creative arts and writing
classificationCode: 47
subject: Language, communication and culture
classificationCode: 4701
subject: Communication and media studies

description: Wikipedia, despite its volunteer-driven nature, stands as a trustworthy repository of information, thanks to its transparent and verifiable processes. However, Large Language Models (LLMs) often use Wikipedia as a source without acknowledging it, creating a disconnect between users and Wikipedia’s rich framework. This poses a triple threat to information literacy, Wikipedia’s vitality, and the potential for dynamic, updated information. This article explores the interplay between representation, accessibility, and LLMs on Wikipedia, highlighting the importance of preserving Wikipedia as a space for access, representation, and ultimately advocacy in an increasingly LLM-dominated information landscape. This article contends that, despite being over two decades old, Wikipedia remains vital not only for knowledge accumulation but also as a sanctuary for the future of knowledge representation, championing representation and accessibility in the age of closed-system LLMs.
Use of a human patient simulator with undergraduate nursing students: a prototype evaluation of critical thinking and self-efficacy
Creators: name: Ravert, Patricia Kay McArthur
Publisher: name: University of Utah
Year: 2012
Subjects: Nursing - Study and teaching
Simulated patients

description: An instructional development pilot project with enrichment activities was undertaken to determine the effect of using a human patient simulator (HPS) on critical thinking and self-efficacy in a sample of nursing students. Twenty-five nursing students in their 3rd semester during 2003 at a private university completed the project. Dependent variables were the gain scores from the critical thinking and self-efficacy instruments, with prescores as covariates. Independent variables were the group and learning style. Participants were stratified by learning style and randomly assigned to one of two enrichment activity groups. Group 1 discussed the patient cases in a classroom setting. Group 2 used a HPS to simulate actual patient cases and to perform nursing actions. Comparison of the two groups was performed using a general linear model procedure in which there were two factors, namely group and learning style quadrant, with the pretest score included as a covariate. Neither enrichment group had significant gain in critical thinking disposition scores. However, significant critical thinking skills total gain scores,  F (8, 16) = 20.74, p = .000, and self-efficacy total gain scores, F (8, 16) = 4.58, p = .01, were noted for Groups 1 and 2. The gains were not predicted by learning style or group. Both enrichment groups showed increased critical thinking skills and self-efficacy scores; however, the HPS group was more enthused about learning and expressed a desire for further sessions. The HPS group said "learning by doing was helpful and felt more confident in caring for patients.""
Colonization and susceptibility profile of vaginal yeast isolates in Ekpoma, Edo state Nigeria.
Creators: name: Ifeoma Enweani
Publisher: name: figshare
Year: 2020
Subjects: subject: 110303 Clinical Microbiology
subject: FOS: Clinical medicine

description: Although Candida albicans remains a persistent pathogen in humans, little is known about the relationship between commensal and infecting strains, the origins of infecting strains, transmission of the organism between individuals, and strain specialization. Objective: To outline the colonization profile and susceptibility to azoles of vaginal yeast isolates in Ekpoma, Nigeria.
A new homoisoflavan from Dracaena cinnabari Balf. f. resin: α-glucosidase and COX-II inhibitory activity
Creators: name: Helal, Iman E.
name: Elsbaey, Marwa
name: Zaghloul, Ahmed M.
name: Mansour, El-Sayed S.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: A new homoisoflavan, identified as (3 R)-7-hydroxy-3′,4′-methylenedioxyhomoisoflavan, was isolated from Dracaena cinnabari Balf. f. resin. The structure was elucidated by one- and two-dimensional NMR spectroscopy as well as high resolution mass spectrometry. In addition, a diverse group of flavonoids were isolated, representing homoisoflavans, flavans, flavanones, chalcones and dihydrochalcones. The compounds were evaluated for their α-glucosidase and COX-II inhibition activity. The obtained IC50 values of the tested flavonoids gave an insight about some key structural features to their α-glucosidase and COX-II inhibitory activity. For α-glucosidase inhibitory activity, a flavanone skeleton was favorable over a flavan. For COX-II inhibition, the introduction of a fused heterocyclic ring at the homoisoflavan skeleton enhanced the activity.
Steady-state transfer function analysis of portions of the circulatory system using indicator dilution techniques
Creators: name: Coulam, Craig Merrill
Publisher: name: University of Utah
Year: 2012
Subjects: Computers Modes
Circulatory Pathways

description: A digital computer program has been developed whereby the distribution of dye particle transit times across circulatory pathways can be found from recordings of upstream and downstream indicator dilution curves. This distribution, or transfer function is computed from Fourier series representations of the upstream and downstream indicator curves and makes possible, for the first time, the calculation of transit time distributions independent of the effects of recirculating dye. Since a discontinuity is introduced into the tails of the upstream and downstream curves at the end o£ the indicator sampling, the method requires an iterative approach in the termination of the upstream and downstream curves. The precision of the calculated distribution pattern is determined by comparison of the recorded downstream curve with the results of the convolution of the recorded upstream curve and computed transfer function. The effects of noise, bandwidth, sampling rate and aliasing have been investigated through the use of analog computer models of circulatory pathways. These studies show that the, transfer function description is limited to the bandwidth of the upstream (input) curve. Noise, or variations in magnitude and phase angle o£ input and output curve frequencies, and aliasing effects can introduce oscillations into the time-domain representation of the transfer function as does the use of too few harmonic terms.  Two physiological studies are present which show the applicability of using the above method in the analysis of circulatory dispersion properties. The first study is concerned with the vascular responses (coronary, renal and systemic circuits) to the drugs adenosine triphos-phage, acetylcholine and angiotensin II, The second study shows the circulatory dispersion relationships which exist between lower extremity, renal and systemic circuits before, during and following moderate treadmill exercise.  A third section of the thesis is devoted to the study of catheter-sampling distortion conditions and to the development of means of correcting for such. Transfer function relationships which describe catheter geometry configurations [bends and coils) and blood hematocrit effects are presented.""
Antileishmanial and cytotoxic activity of secondary metabolites from Taberneamontana ventricosa and two aloe species
Creators: name: Andima, Moses
name: Ndakala, Albert
name: Derese, Solomon
name: Biswajyoti, Sarkar
name: Hussain, Aabid
name: Yang, Li Jun
name: Akoth, Otieno Elsie
name: Coghi, Paolo
name: Pal, Chiranjib
name: Heydenreich, Matthias
name: Wong, Vincent Kam-Wai
name: Yenesew, Abiy
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: In this study, the antileishmanial and cytotoxic activities of secondary metabolites isolated from Tabernaemontana ventricosa Hochst. ex A. DC., Aloe tororoana Reynolds, and Aloe schweinfurthii var. labworana Reynolds were investigated. Overall, nineteen known compounds were isolated from the three plant species. The compounds were characterized based on their spectroscopic data. Voacristine and aloenin were the most active compounds against promastigotes of antimony-sensitive Leishmania donovani (IC50 11 ± 5.2 μM and 26 ± 6.5 µM, respectively) with low toxicity against RAW264.7, murine monocyte/macrophage-like cells. The in silico docking evaluation and in vitro NO generation assay also substantially support the antileishmanial effects of these compounds. In a cytotoxicity assay against cancer and normal cell lines, ursolic acid highly inhibited proliferation of lung cancer cells, A549 (IC50 6.61 ± 0.7 μM) while voacristine was moderately active against human liver cancer cells, HepG2 (IC50 23.0 ± 0.0 μM). All other compounds were inactive against the test parasites and cell lines.
Delta- and mu-conotoxins : peptides from cone snail venoms that selectively affect tetrodotoxin-sensitive and tetrodotoxin-resistant volatge-gated sodium channels.
Creators: name: West, Peter J
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Conotoxins
subject: Cone Snail
subject: Venoms
subject: Voltage-Gated Sodium Channels
subject: Tetrodotoxin
subject: Neurology

description: Cone snails ( Conus ) are carnivorous marine gastropods that feed on such diverse prey as marine worms, molluscs, and most remarkably, fish. They have accomplished this by developing a vast number of specialized toxins that selectively target particular receptors and ion channels in the nervous systems of their prey. These Conus toxins, collectively called conotoxins, are usually small, highly disulfide-rich peptides.  The primary aim of the work presented in this dissertation was to characterize the activities of delta- andmu-conotoxins. Peptides belonging to these conotoxin families selectively affect tetrodotoxin-sensitive (TTX-sensitive) and tetrodotoxin-resistant (TTX-resistant) voltage-gated sodium channels (VGSCs). An understanding of the pharmacology and physiological effects of these conotoxins should allow them to be used as functional probes for VGSCs.  Chapter 3 describes the activities of delta-conotoxins PVIA and SVIE from the fish-hunting cone snails Conus purpurascens and Conus striatus respectively. Both of these toxins inhibit the inactivation kinetics and affect the voltage-sensing properties of sodium channels in frog sympathetic neurons. While the effects of delta-PVIA were reversed by washing, those of delta-SVIE were largely irreversible over the time course of these experiments. We conclude that the effects of delta-PVIA and delta-SVIE are remarkably similar to those of site-3 VGSC toxins from other venomous organisms.  Chapters 4 and 5 describe the inhibition of TTX-sensitive and TTX-resistant VGSCs in frog sympathetic and dorsal root ganglia neurons by mu-conotoxins. Chapter 4 describes the activity of ?-conotoxin SmIIIA, which may be the first selective antagonist of TTX-resistant VGSCs. Chapter 5 compares SmIIIA's activity with other "new" and "classic" mu-conotoxins. It is concluded that the classic ?-conotoxin, PIIIA, does not inhibit TTX-resistant VGSCs, while "new" mu-conotoxins SmIIIA, S3.2, and Kn3.1 do. Furthermore, S3.2 and Kn3.1 may be even more selective than SmIIIA for TTX-resistant VGSCs. Chimeras between SmIIIA and PIIIA were generated. These chimeras reveal that the C-terminal half of "new" mu-conotoxins contains sequence features important for their selective inhibition of TTX-resistant VGSCs.
Brief an Gottfried Kirch
Creators: name: Schultz, Gottfried
Publisher: name: [s.n.]
Year: 1682

description: von Gottfried Schultz
description: Mit rotem Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire April 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
The great white umpire in Palestine: British economic polices and Arab grievances, 1920-1936
Creators: name: Gabe, Evan Bradley
Publisher: name: University of Utah
Year: 2013
Subjects: British - Palestine
Palestine - Economic conditions - 1917-1948
Palestine - History -1917-1948
Great Britain - Foreign relations - Palestine
Palestine

description: This thesis examines the consequences of British economic policies in Palestine from 1920-1936. The government of Palestine needed to accommodate the economic demands of the Zionists, the Arabs, the international community, and the British Empire, but with so many commitments, the British often ignored the needs of the Arabs in order to placate the other groups. Many economic policies had unintended consequences which greatly angered the Arabs, hurt their sector of the economy, or both. This thesis attempts to break away from the simple approach of viewing Palestine through the prism of the dual commitments to the Zionists and the Arabs by broadening the scope and looking at British obligations to the international community and the British Treasury. In addition, the present work examines British attitudes towards the Zionists and the Arabs in regard to developing the country. It also uses Arab complaints to paint a more complete picture of British economic policies.
A social-ecological approach to examine body mass index during early childhood in Ireland
Creators: name: Jabakhanji, Samira Barbara
Publisher: name: Royal College of Surgeons in Ireland
Year: 2020
Subjects: Health Care

description: Background: Childhood overweight and obesity (OWOB) is associated with adult obesity (10) and ill-health (11); however the prevalence among young children in Ireland is unknown. For prevention programmes to target those children most in need, risk factors of OWOB and critical time points when these factors occur need to be identified. This thesis investigated in-depth the OWOB prevalence and risk factors among young children in Ireland.
Methods: A literature review was conducted to identify a suitable child growth criterion for young children in Ireland. Prevalence of OWOB was assessed through secondary analysis of the Growing Up in Ireland National Longitudinal Study of Children. Families in the nationally representative infant cohort were interviewed when the children were nine months (n=11,134), three years (n=9,793) and five years old (n=9,001). At all ages, standardised weight and length/height among other variables were collected from the children and their caregivers. Associations of explanatory variables with children’s OWOB were analysed using binary logistic regression, and with longitudinal changes in body mass index (BMI) using multilevel regression models.
Results: Using the World Health Organization growth standard and growth reference to define OWOB (using the 1-z-score threshold), 40.4% of the nine-month-old children had OWOB, 45.7% of the three-year-olds and 31.5% of five-year-olds. At all ages, high birth-weight-for-gestational-age, late birth and rapid infant weight gain were strongly related to OWOB and elevated BMI. At specific ages, caregiver OWOB and education, household income, family structure, ethnic background, geographic region, screen use, sleep duration, antibiotic use and childcare were also associated with OWOB and longitudinal changes in BMI.
Discussion: Biological, material and psychosocial factors contribute to the high prevalence of early childhood OWOB seen in Ireland and risk factors should be targeted simultaneously to lower OWOB levels. Prevention should start as early as possible and be maintained throughout the early childhood.
Brief an [Gottfried Kirch]
Creators: name: Schultz, Gottfried
Publisher: name: [s.n.]
Year: 1692

description: von Gottfried Schultz
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire April 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
Secondary metabolites from a peanut-associated fungus Aspergillus niger IMBC-NMTP01 with cytotoxic, anti-inflammatory, and antimicrobial activities
Creators: name: Quang, Tran Hong
name: Phong, Nguyen Viet
name: Anh, Le Ngoc
name: Hanh, Tran Thi Hong
name: Cuong, Nguyen Xuan
name: Ngan, Nguyen Thi Thanh
name: Trung, Nguyen Quang
name: Nam, Nguyen Hoai
name: Van Minh, Chau
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Chemical investigation of a peanut-associated fungal strain Aspergillus niger IMBC-NMTP01 resulted in isolation and identification of 14 secondary metabolites, including two new, epi-aspergillusol (1) and aspernigin (3), and 12 known compounds: pyrophen (2), 2-(hydroxyimino)-3-(4-hydroxyphenyl)propanoic acid (4), aspergillusol A (5), rubrofusarin B (6), nigerasperone A (7), fonsecin (8), TMC-256C1 (9), pyranonigrin A (10), orlandin (11), nigerasperone C (12), asperpyrone A (13), and 5-(hydroxymethyl)-2-furancarboxylic acid (14). Compounds 9, 12-14 showed cytotoxicity toward all six human cancer cell lines, including HepG2, KB, HL-60, MCF-7, SK-Mel2, and LNCaP, with IC50 values ranging from 8.4 to 84.5 µM, compounds 3-5 were cytotoxic against five cancer cell lines except HepG2, whereas 1 exhibited cytotoxicity toward HepG2, KB, and MCF-7 cells. All of the compounds, except 2 and 13, inhibited NO overproduction in LPS-induced RAW264.7 cells. In addition, all of the compounds displayed antimicrobial effects against Enterococcus faecalis, whereas 13 compounds, except 10, significantly inhibited the growth of the yeast Candida albicans.
Biophysical properties of hepatic cells: active sodium transport as a primary determinant of bile formation in the rat.
Creators: name: Rollins, Douglas Earl
Publisher: name: University of Utah
Year: 2012
Subjects: Rat
Laboratroy Animals

description: The importance of the biliary excretion of inorganic ions in bile formation was investigated.  The distribution of erythritol-14C, inulin-3H, sodium, potassium and chloride between plasma, liver cells and bile was measured in rats with increased bile flow produced either by taurocholate infusion or by chronic administration of phenobarbital and decreased bile flow produced by acute ileal resection.  Liver cell and bile duct potentials (PD) were measured in each animal. A 37.6 (±0.5 SEM) mV PD was recorded across the liver cell sinusoidal membrane (cell negative with respect to extracellular fluid).  The PD across the liver cell canalicular membrane was estimated to be 32 mV (cell negative with respect to bile).  The results demonstrate that sodium is actively transported out of the liver cell across the sinusoidal and canalicular membranes.  Potassium is transported into the liver sell across these membranes.  Based on the following observations the active transport of sodium into bile is considered to be the primary determinant of bile flow in the rat.  1) There is a large frication of bile flow which is bile salt-independent.  2) There is virtually no sodium-independent bile flow.  3) There is a close correlation between bile flow and sodium excretion.  4) Increasing sodium excretion increases bile flow independent of taurocholate excretion. 5) Increasing taurocholate excretion requires that sodium excretion also increases before an increase in bile flow can be observed.  6) The daily administration of phenobarbital (75 mg/kg) for 4 days increases bile flow and sodium excretion by 30%, whereas taurocholate excretion decreases by 46%.
Zwischen Goldenen Äpfeln und Ruinen – 300 Jahre Gartengeschichte Eremitage
Creators: name: Oelwein, Cornelia
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Ausstellung: Zwischen Goldenen Äpfeln und Ruinen – 300 Jahre Gartengeschichte Eremitage. Sonderausstellung im Neuen Schloss Eremitage (Bayreuth) bis 16. Oktober 2016.
description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 2 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Hustrulid bar - a dynamic strength test and its application to the cautious blasting of rock
Creators: name: Johnson, Jeffrey Craig
Publisher: name: University of Utah
Year: 2012
Subjects: Blast damage blast design
Blast design
Blasting
Dynamic rock strength blast damage
Hopkinson bar
Hustrulid bar

description: Drill and blast is a common mining technique. It is used to damage the rock for extraction and leave the remaining rock for support. Its perfection is the goal of cautious blasting. The theory of cautious blasting describes the relationships connecting the blasthole, the explosive, and the rock mass to the resulting damage. Blast damage is caused by the propagation of stress waves and the expansion of gas. The focus is on the  damage caused by the stress waves, in particular, the radial compressive stress wave. Stress waves decay by three mechanisms: geometric spreading, damage, and seismic attenuation. Where the stress has decayed to its dynamic compressive strength the damage ends. Therefore, if one knows the initial stress, the amount of stress decay, and the strength, then the damage distance can be computed.
Baudenkmale gefährdet – Baudenkmale gerettet
Creators: name: Oelwein, Cornelia
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 2 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Scutellaria orientalis subsp. Bornmuelleri: phytochemical composition and biological activities
Creators: name: Gharari, Zahra
name: Aghajanzadeh, Mozhgan
name: Sharafi, Ali
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: The medicinal plant, Scutellaria orientalis, is used for the treatment of several diseases in North-western of Iran. The purpose of this study was to investigate the phytochemical content, cytotoxicity assay against SW-480 and HCT-116 cells and anti-haemolytic activities using HPLC-PDA, GC/MS, MTT and spectrophotometry methods, respectively. Phytochemical screening revealed the presence of different terpenoids and flavonoids such as baicalin, tricin and wogonin and also some of the other medicinally active compounds such as conhydrine and cannabidiol. MTT results revealed that HCT-116 cells were more sensitive to examined extracts compared with SW-480 cells. Methanol extract had the most anti-proliferative activity against HCT-116 and SW-480 cells at 48 h with IC50 values of 614.5 and 592.3 µg/mL, respectively. Also, all samples had no significant haemolytic effect on human erythrocytes. Our results revealed that S. orientalis root extract has a promising anticancer activity, indicating the presence of major anti-cancer agents on human colon cell lines.
Nuclear Magnetic resonance spectroscopy of escherichia coli tRNA (LYS) and the t RNA)LYS)-HIV RNA complex
Creators: name: Nair, Vinod
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Human tRNA(Lys,3) is the sole primer of HIV reverse transcription. The interaction between the tRNA and HIV RNA was studied by using E. coli tRNA(Lys) as a model.  A reversed phase C4 method was developed for fractionation of tRNAs. This method was used to isolate (15)N labeled tRNA(Lys) from E. coli grown in minimal medium. The modification status of the isolated tRNA was verified by RNase Tl digestion followed by LC/MS. The isolated tRNA(Lys) was characterized by NMR. Data from (1)H and (1)H-(15)N spectroscopy were used to assign residues in the tRNA.  An RNA construct based on the HIV Mai sequence was designed with sequence modifications to favor binding to E.coli tRNA(Lys). The construct was designated M3EC. The construct contained highly conserved elements of the viral RNA that are known to interact with the tRNA primer during reverse transcription. M3EC was transcribed in vitro from a DNA template by using rNTPs and T7 RNA polymerase. The tRNA-M3EC complex was formed by heat annealing. Specific binding of MSEC to E. coli tRNA(Lys)  and complex formation was analyzed by an electrophoretic mobility shift assay.  The tRNA(Lys)-M3EC complex was characterized by NMR. Residues in the complex were assigned by using data from (1)H and (1)H-(15)N HSQC experiments. Evidence for extensive interaction between the two RNA molecules was seen. Some tertiary interactions in the free tRNA were disrupted. Extensive disruption of base pairs in the acceptor and T?C stems was also observed. These bases formed new base pairs with the M3bC residues, as evidenced by appearance of new peaks m the HSQC spectrum. There was also proof of interaction between the A-loop and the tRNA anticodon. The NH11 proton of t(6)^A37 in the anticodon gave two signals in the complex, resulting from bound and free states. The change in chemical shift of the t(6)A proton indicates that modified nucleotides in the anticodon play a significant role in the A-loop/anticodon interaction. It also supports the kissing hairpin model proposed for the interaction.
Brief an Gottfried Kirch
Creators: name: Schultz, Gottfried
Publisher: name: [s.n.]
Year: 1686

description: von Gottfried Schultz
description: Mit roten Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire April 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
Brief an [Johann III Bernoulli]
Creators: name: Sermage, Peter Johann Nepomuk von
Publisher: name: [s.n.]
Year: 1789

description: von P[eter] [Johann Nepomuk] von Sermage
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Mai 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
Measuring the impact of lowering the barriers to information retrieval on the use of a clinical reference knowledge base at the point of care.
Creators: name: Reichert, James Charles
Publisher: name: University of Utah
Year: 2012
Subjects: Patient Care Planning
Delivery of Health Care

description: Physicians have unmet information needs at the point of care. These needs have been recognized for many years and yet continue to exist despite extensive efforts by educators through Continuing Medical Education (CME), Evidence Based Medicine (EBM) programs, and publications intended to meet those needs. Most of the research done to meet information needs at the point of care has evaluated Medline, accessed via the search engine PubMed, but has had little success as noted by limited use of the application at the point of care and studies showing decreasing usage over time. The work described in this dissertation lowers the barriers to information retrieval by decreasing the time and number of mouse clicks required to find an answer, offering the user after one mouse click potential questions the system can answer, and tailoring the application to meet the user's information needs based on the clinical context under consideration. The application was implemented in late September 2002 and evaluated over a 27-month period. The assumption is: if the barriers to information retrieval are lowered, physicians will use the application more over time. The usage of the application was measured objectively and subjectively through an audit table and Likert questionnaire. The use of the infobutton grew in a linear fashion over the 27-month period by a group of experienced practicing physicians. Physicians who used the infobutton used it more as time progressed. Of the physicians who responded to the Likert questionnaire 87% (20 out of 23) thought the infobutton added significant value to the Electronic Medical Record (EMR). In concluding we agree with Ely who thinks that not only should doctors frame their questions better but the authors really need to frame their answers better. As this study and others have shown the current information need at the point of care is not for better quality information but faster access to quality information that answers specific clinical questions at the point of care.
Brief an [Johann Friedrich] Henkel
Creators: name: Brevern, Karl Hermann von
name: Schumacher, Johann Daniel
Publisher: name: [s.n.]
Year: 1740

description: von [Karl v.] Brevern und J[ohann] D[aniel] Schumacher
description: Unterschriften Autograph
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Druck: Materialy dlja istorii imp. Akademii nauk, 1887, 4, S.448
description: Verzeichnung=Description=Inventaire Mai 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
Uncovering the realities of prostitutes and their children in  a cross national comparative study between India and the U.S.
Creators: name: John-Fisk, Hena
Publisher: name: University of Utah
Year: 2013
Subjects: Children of prostitutes
India
Prostitute
Sex workers
Stakeholders
U.S.

description: This qualitative study examines the needs and challenges of prostitutes and their children. A review of research regarding prostitutes indicates that the needs and experiences of prostitutes, their children, and stakeholders who provide services to this population have been neglected. The first part of the study looks at the challenges prostitutes face trying to be successful mothers. The study was conducted in the U.S. and India. The findings of this study reveal that these women face difficulties in their daily lives. Due to the distinct differences between the interventions and policies in both countries, each group shares a different relationship with their children. The findings of the study strongly advocate for joint programs for prostitutes and their children to help ensure them all a better future. The second part of the study was conducted with children of prostitutes who live with their mothers in red light areas of Mumbai, India. The participants discussed the experiences and challenges they face in their daily lives as children of prostitutes, their relationships with their mothers, and support programs needed for a better life. All of the child participants conveyed that they did not want to be separated from their mothers. The children had good relationships with their mothers and wanted to support their mothers as they aged. The final part of the study examines challenges stakeholders encounter while providing services to prostitutes and their children. The stakeholders also shared their views about the difficulties that children of prostitutes and their mothers face. The stakeholders expressed what support they thought would be helpful for this group. This study is presented in the form of three distinct scholarly manuscripts. Each of the manuscripts has its own research questions and findings that contribute to the overall research agenda in unique ways. Each study makes its own specific recommendations for social work policy, practice, and research. Together, the three manuscripts add to our knowledge about prostitutes as mothers, as well as defining their children's needs and challenges.
Parkomanie – Die Gartenlandschaften des Fürsten Pückler
Creators: name: Redaktion, Die
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Ausstellung: Parkomanie – Die Gartenlandschaften des Fürsten Pückler, Bundeskunsthalle, Friedrich-Ebert-Allee 4, 53113 Bonn. Garten und Ausstellung: bis 18. September 2016.
description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 2 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
PER-ARNT-SIM kinase regulates nutrient utilization and growth
Creators: name: Cardon, Caleb Michael
Publisher: name: University of Utah
Year: 2012
Subjects: Growth
Kinase
Metabolism
Nutrient
PAS
TOR
PER-ARNT-SIM kinase
Bioenergetics

description: There is a fundamental connection between growth and nutrient availability. An inbalance between energy intake and energy expenditure can lead to the common diseases of the developed world, including type 2 diabetes, obesity, heart disease and cancer, as well as less common diseases such as anorexia, malnutrition and sarcopenia. The tight link between growth and nutrient availability is extended beyond the whole body level down to a cellular level. There exist cell autonomous signaling mechanisms that allow the cell to detect the environmental conditions and decide to grow, through increase in cell size or cell division. Malfunctions in these signaling pathways are fundamental to many  of the diseases related to energetic misregulation. Many of the proteins that are central to these signaling pathways have also become good therapeutic targets.  Two well characterized proteins that are central to cellular energy balance are AMPK and TOR. In response to depleted cellular ATP levels AMPK is activated in order to up-regulate ATP generating pathways and downregulate ATP consuming pathways, including growth. However as nutrients become available TOR is rapidly activated in order to efficiently utilize the available nutrients for growth. As our understanding of the function of these two proteins has increased, AMPK and TOR have become effective therapeutic targets. PAS kinase is a newly characterized serine/threonine kinase that can respond to the extracellular conditions in order to regulate nutrient partitioning and provide a progrowth signal. We show here that in budding yeast PAS kinase can respond to environmental cues to phosphorylate the metabolic enzyme Ugp1. P-Ugp1 then nucleates the formation of a unique signaling complex that includes Rom2 and Ssd1. Complex formation is able to activate the small GTPase Rho1, which functions as a progrowth signal. We also show that PASK-/- mice are resistant to the damaging effects of a high fat diet, specifically, obesity, insulin resistance and hepatic steatosis. This protection is likely due to the increased metabolic rate of PASK-/- mice. The hypermetabolic phenotype of the PASK-/- can be recapitulated in cultured cells, which indicates that the increased metabolic rate is due to a cell autonomous change in metabolism. Further characterization of PAS kinase may lead to novel therapeutic strategies to treat the metabolic syndrome.
Chemical composition and bioactivities of essential oils from different plant parts of Ferula pseudalliacea Rech.f. as an endemic plant from Iran
Creators: name: Dastan, Dara
name: Hamah-Ameen, Baram Ahmed
name: Salehi, Peyman
name: Ghaderi, Hiva
name: Miran, Mansour
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: 60506 Virology

description: The essential oils of leaf, flower, immature and mature fruit from Ferula pseudalliacea (Apiaceae) which grow wildly in Iran as an endemic plant were obtained by hydro-distillation and subsequently analysed by GC-FID and GC-MS. The oils obtained in yields 0.4-4.0% (w/w) and the analysis of GC-MS/FID chromatogram was resulted in the identification of 43-47 compounds, representing 90.9 − 96.7% of the total oils. α-Pinene was the main compound in all samples. The oils exhibited mild activity against Bacillus pumilus, Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus with or more than 15 mm zones of growth inhibition and MIC values of 9-15 mg/ml. Essential oil of immature and mature fruits showed potent antioxidant activity with IC50 values of 35.4 ± 0.4 and 39.1 ± 0.4 µg/mL, respectively. So, this plant as an antibacterial and antioxidant agent can be useful in food and medicine industry.
Die Hohkönigsburg in der Karikatur – Albert Weisgerber, Maler und Karikaturist
Creators: name: Fischer, Ludger
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 2 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Brief an [Gustav Ulrich] Raiser, [Michail Vasilʹevič] Lomonosov und [Dmitrij Ivanovič] Vinogradov
Creators: name: Korff, Johann Albrecht von
name: Goldbach, Christian
name: Schumacher, Johann Daniel
Publisher: name: [s.n.]
Year: 1739

description: von [Johann Albrecht v.] Korff, [Christian] Goldbach und J[ohann] D[aniel] Schumacher
description: Unterschriften Autograph
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Druck: Materialy dlja istorii imp. Akademii nauk, 1887, 4, S.149-50
description: Verzeichnung=Description=Inventaire Mai 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
Brief an [Johann III Bernoulli]
Creators: name: Sermage, Peter Johann Nepomuk von
Publisher: name: [s.n.]
Year: 1788

description: von P[eter] [Johann Nepomuk] von Sermage
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Mai 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
Brief an [Johann III Bernoulli]
Creators: name: Schwartz & Co
Publisher: name: [s.n.]
Year: 1781

description: Bl. 154r: Anmerkung von Bernoulli
description: von Schwartz und Co.
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Druck: Johann Bernoulli's Sammlung kurzer Reisebeschreibungen und anderer zur Erweiterung der Länder- und Menschenkenntniss dienender Nachrichten. - Berlin : bey dem Herausgeber, ; Leipzig : in der Buchhandlung der Gelehrten, 1782, 5, S.436-439
description: Verzeichnung=Description=Inventaire Mai 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
Verleihung des Großen Denkmalpreises der Stiftung der Deutschen Burgenvereinigung 2016
Creators: name: Holdorf, Martina
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 2 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Isolation and neuroprotective prospective of novel bioactive compound “3-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl) prop-2-en-1-one” against ketamine-induced cognitive deficits in schizophrenia: an experimental study
Creators: name: Chintha, Venkataramaiah
name: Wudayagiri, Rajendra
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: For the first time a new flavonoid compound is isolated from the seeds of Celastrus paniculatus (CP) using different chromatographic techniques and it’s structure is predicted as “3-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one” by employing various spectroscopic studies. The neuroprotective potential of this flavonoid was evaluated against ketamine-induced cognitive deficits with special reference to cholinergic system in vivo. The compound has exhibited significant neuroprotective property against ketamine-induced cholinergic alterations in different brain regions of rat which are restored to normal during the treatment with the compound on par with the reference compound, clozapine. Moreover, the isolated compound was found to be non-toxic to the animal during the treatment which indicates its safety in any human health related applications and can add value to the new drug development. In conclusion, this is the first study of new flavonoid compound of CP and its protective efficacy against schizophrenia.
Die Leuchtenburg bei Seitenroda/Thüringen – zu den archäologischen Untersuchungen in der Vorburg mit ersten Siedlungsspuren aus dem frühen 12. Jahrhundert
Creators: name: Spazier, Ines
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 2 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Brief an J[ohann] [II] B[ernoulli]
Creators: name: Schöpflin, Johann Daniel
Publisher: name: [s.n.]
Year: 1762
Subjects: Altdorf, von

description: Schöpflin bittet Joh. II B., einen Schützling der Marquise d'Urfé (namens von Altdorf) zu empfangen und der Marquise direkt nach Sulzbach bei Colmar zu antworten. In Karlsruhe habe man gerade mit dem Druck der Geschichte des Hauses Baden begonnen.
description: von [Johann Daniel] Schöpflin
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Druck: Johann Daniel Schöpflin, Wissenschaftliche und diplomatische Korrespondenz, hrsg. v. J. Voss, Stuttgart (Thorbecke) 2000, p.351
description: Datenimport aus LIDOS / Bernoulli (2004-07-02)
Die Leuchtenburg bei Seitenroda (Thüringen) - zur Baugeschichte der Kernburg
Creators: name: Fritzsche, Christian
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 57 Nr. 2 (2016): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
A nonlinear/inelastic rooftop tuned mass damper frame
Creators: name: Johnson, Jerod Greg
Publisher: name: University of Utah
Year: 2012
Subjects: Buckling restrained brace
Dynamic
Inelastic
Nonlinear
Rooftop
Tuned mass damper

description: Reduction of a building's response to earthquake ground motion has been the focal point behind considerable research and structural engineering innovation in recent decades. For many years, engineers have understood that altering a structure's fundamental period offers the greatest opportunity for reducing its response to seismic  ground motion. Innovations such as base isolation have been developed which enable a building's fundamental period to be out-of-phase with the soil dependent dynamic properties of the site, the result being a significant reduction of seismic accelerations,  forces and overall damage. Other approaches utilize highly ductile structural frames which offer the benefit of sustaining service loads while being subjected to significant lateral distortion. Such systems enable lengthening of the fundamental period of the  structure during nonlinear response which typically reduces the acceleration response.  Furthermore, ductile systems utilize creative methods to dissipate earthquake energy in a stable manner to prevent the earthquake input energy from causing damage at sensitive regions of structural assemblies. Creative applications of mass and stiffness utilized as  penthouse enclosures at the rooftop of structures offer the potential for changing a building's structural dynamic properties. This method has been termed a rooftop tuned  mass damper frame (RTMDF). The incorporation of specific yielding mechanisms within these structures offers the potential of further modifying a structure's dynamic properties while also introducing methods for increased energy dissipation. The net result of this method is an inexpensive retrofit measure to improve the seismic performance of existing structures. The method also offers the potential for improving  the expected performance of new structures or reducing construction costs of the seismic system.  This research investigates the effectiveness of buckling restrained braces in rooftop tuned mass damper frames for reducing seismic response. This approach could  be implemented for a relatively low cost at the roof of the suited structure. It will have the benefit of introducing designated yielding members (DYM's) for seismic energy dissipation in a controlled manner and will create an opportunity to lengthen the fundamental period of the original structure. These effects are complementary and offer the potential for reduction of seismic acceleration response and reduction of earthquake demand on the base structure.