cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Octupolar platforms for applications in Non Linear Optics
Creators: name: Triadon, Amedee
Publisher: name: The Australian National University
Year: 2017
Subjects: NLO
non linear optics
organic chemistry
organometallic chemistry
platinum
TPEF
two-photon excited fluorescence
photosensitiser
photosensitizer
bioimaging

description: During this Ph.D work, we were able to synthesize a series of 2D octupoles as well as study their linear and nonlinear optical properties. These molecular architectures are known for their good NLO properties, especially their two-photon absorption properties (TPA). In this thesis, we focused most of our work on isocyanurate and triazine cored octupoles. Isocyanurates are quite understudied even though they have recently proven to be promising for TPA applications, whereas triazines were already known for their good TPA properties. In this respect we started out by the synthesis and characterization of a series of organic isocyanurates. These compounds allowed us to derive useful structure/property relationships. We also synthesized a series of analogous triazines possessing the same donor groups than the isocyanurate series, in order to be able to compare the effect of the core in these two series. This study allowed us to select two candidate chromophores for one of the applications of TPA, two-photon photodynamic therapy (2PPDT). We then focused our efforts on making hydrosoluble version of our model compounds for 2PPDT. Thanks to a collaboration with the group of Magali Gary-Bobo and Manuel Garcia (UMR 6247, Montpellier), photosensitization and biocompatibility results have been obtained in vitro and in vivo. In the last part of this work, the structure/property relationships derived on organic molecules have been used to design a new series of cyclometalated platinum complexes.
Additional file 1 of Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate)
Creators: name: Kudo, Hirotaka
name: Ono, Sho
name: Abe, Kenta
name: Matsuda, Mami
name: Hasunuma, Tomohisa
name: Nishizawa, Tomoyasu
name: Asayama, Munehiko
name: Nishihara, Hirofumi
name: Chohnan, Shigeru
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 1: Figure S1. Confirmation of plasmids carried by the prepared transformants. Figure S2. Growth curves of the transformants carrying the pha genes from M. aeruginosa. Table S1. Plasmid retention rates of the E. coli transformants during P(3HB) production. Table S2. Oligonucleotide primers used in this study. Figure S3. Cloning of the pha genes from Microcystis aeruginosa NIES-843 (A) and sequencing of the genes cloned in pQE-60, designated pQE-Ma-phaABEC (B).
Fano-type interference in quantum dots coupled between metallic and superconducting leads
Creators: name: Baranski, J.
name: Domanski, T.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We analyze the quantum interference effects appearing in the charge current through the double quantum dots coupled in T-shape configuration to an isotropic superconductor and metallic lead. Owing to proximity effect the quantum dots inherit a pairing which has the profound influence on nonequilibrium charge transport, especially in the subgap regime |eV| < Delta. We discuss under what conditions the Fano-type lineshapes might appear in such Andreev conductance and consider a possible interplay with the strong correlation effects.
description: 7 pages, 7 figures
Multiplicities from black-hole formation in heavy-ion collisions
Creators: name: Kiritsis, Elias
name: Taliotis, Anastasios
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The formation of trapped surfaces in the head-on collision of shock waves in conformal and non-conformal backgrounds is investigated. The backgrounds in- clude all interesting confining and non-confining backgrounds that may be relevant for QCD. Several transverse profiles of the shocks are investigated including distributions that fall-off as powers or exponentials. Different ways of cutting-off the UV contributions (that are expected to be perturbative in QCD) are explored. Under some plausible simplifying assumptions our estimates are converted into predictions for multiplicities for heavy-ion collisions at RHIC and LHC.
description: 38 pages, 5 figures, 4 tables; minor typos corrected, figure 5 added, references added
Additional file 2 of Effectiveness of a screening tool to assess prevention and rehabilitation needs of 45 to 59 years old in primary care – study protocol of a pragmatic randomized controlled trial (PReHa45)
Creators: name: Burchardi, Jennifer Marie
name: Spyra, Karla
name: Brünger, Martin
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: Additional file 2.
Synthesis and characterization of ruthenium complexes with (N-N)(P-P) and (N-P)2 donor sets
Creators: name: Yang, Xinwei
Publisher: name: Canberra, ACT : The Australian National University
Year: 2016
Subjects: Ruthenium complexes
nonlinear optics
donor set
synthesis and characterization

description: Since the discovery of nonlinear effects, both the theory and measurement techniques have been developed significantly, especially since the invention of the laser. However, structure-NLO property relationships for organometallics as well as their NLO mechanisms are far less explored than those of organic molecules and inorganic salts. The greater flexibility and exceptionally large NLO responses of organometallic compounds attracts chemists to this field. Modification of coordinated co-ligands in organometallic systems has influence on the NLO merit by introducing new electronic charge-transfer transitions, oxidation state and coordination sphere of the metal centers. In this work, the donor sets of the ruthenium complexes were modified from the most investigated (P-P)(P-P) to (N-N)(P-P) and (N-P)2 and a series of ruthenium complexes were synthesized and characterized. In Chapter 2, the study of the Ru(N-N)(P-P) complexes is detailed. Three bidentate diphosphine ligands (dppe, dppb and dppf) and one diimine ligand (tert-Bu-bpy) were selected for this study as the diphosphine and diimine ligands, respectively. Ruthenium halide and mono-alkynyl complexes were obtained successfully. Their optical, electrochemical and spectroelectrochemical properties were examined and are discussed. The formation of eta3- and eta1-butenynyl complexes was confirmed by single-crystal X-ray diffraction. Attempts towards bis-alkynyl complexes were made, but no conclusive evidence could be obtained to confirm the successful synthesis of this species. In Chapter 3, the focus of the work is the study of ruthenium complexes with a (N-P)2 donor set. Two iminophosphine ligands, 2-(diphenylphosphino)pyridine (PPh2py) and 8-(diphenylphosphino)quinoline (PPh2qn), were selected for this study. The cis-RuCl2(N-P) complexes and the corresponding dimers were synthesized and characterized. Their optical and electrochemical properties were measured and are discussed. In Chapter 4, the quadratic and cubic nonlinear optical properties of organometallic complexes were explored by hyper-Rayleigh scattering (HRS) and frequency-depentdent Z-scan techniques, respectively. The first hyperpolarizabilities of the ruthenium halide and mono-alkynyl complexes described in Chapter 2 were determined by HRS measurements. The second hyperpolarizabilities of some organometallic complexes synthesized by the Humphrey group and the collaborators were measured by the Z-scan technique.
Topics in the asymptotic analysis of linear and nonlinear eigenvalue problems
Creators: name: Lindsay, Alan Euan
Publisher: name: University of British Columbia
Year: 2010

description: In Applied Mathematics, linear and nonlinear eigenvalue problems arise frequently when characterizing the equilibria of various physical systems. In this thesis, two specific problems are studied, the first of which has its roots in micro engineering and concerns Micro-Electro Mechanical Systems (MEMS). A MEMS device consists of an elastic beam deflecting in the presence of an electric field. Modelling such devices leads to nonlinear eigenvalue problems of second and fourth order whose solution properties are investigated by a variety of asymptotic and numerical techniques. The second problem studied in this thesis considers the optimal strategy for distributing a fixed quantity of resources in a bounded two dimensional domain so as to minimize the probability of extinction of some species evolving in the domain. Mathematically, this involves the study of an indefinite weight eigenvalue problem on an arbitrary two dimensional domain with homogeneous Neumann boundary conditions, and the optimization of the principal eigenvalue of this problem. Under the assumption that resources are placed on small patches whose area relative to that of the entire domain is small, the underlying eigenvalue problem is solved explicitly using the method of matched asymptotic expansions and several important qualitative results are established.
Delineation of Igneous Rocks on Western Axel Heiberg Island Using Geopotential Data and Satellite Imagery
Creators: name: Mosstajiri, Tina
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Geophysics
subject: Remote Sensing
subject: Igneous Rocks
subject: Axel Heiberg Island
subject: Silica content

description: Remote predictive mapping can provide a base for geological mapping. This thesis investigates different methods for remotely mapping the igneous rocks and their host sedimentary rocks on Axel Heiberg Island, using the already available data sets. Axel Heiberg Island has been chosen as the platform for establishing the most suitable method of mapping igneous rocks and other geological features in the Canadian Arctic Archipelago. The igneous rocks on Axel Heiberg Island are important to understand and study because of their impact on the petroleum system and energy resources that they may contain, and because of the possibility of unravelling the debatable tectonic history of Canadian Arctic Archipelago. To identify the geological information of the study area three remote predictive mapping approaches have been studied. The first remote predictive approach uses remote sensing techniques such as color composite and band ratio to highlight the igneous rocks on Axel Heiberg Island. The satellite sensors that have been employed to analyse the geological information on the surface of the study area are: ASTER and LANDAST satellite images. Spectral correlation technique is employed for the second and third approach. For the second mapping approach gravity and magnetic field anomalies are spectrally correlated and filtered. The filtered gravity and magnetic field anomalies provided key constrains on analysis of geological features, especially igneous rocks and salt domes. The same procedure has been used to spectrally correlate magnetic field anomalies and silica weight percentage of surface rocks derived from ASTER thermal bands. The first remote predictive mapping technique proved to be an effective technique for initial assessment of the study area and highlighting the target geological features. Using color composite technique it was inferred that the igneous rocks in the study area have the highest iii reflectance in Landsat band3 and ASTER band2. The results in the second approach were constrained by low resolution of gravity data; however the thickness trend of igneous rocks and salt domes were revealed. The third approach proved to be the most effective among the other two approaches, where result map matched well with the only available accurate geological map of the study area.
Do stellar winds play a decisive role in feeding AGN?
Creators: name: Davies, R.
name: Burtscher, L.
name: Dodds-Eden, K.
name: de Xivry, G. Orban
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: While the existence of a starburst-AGN connection is undisputed, there is no consensus on what the connection is. In this contribution, we begin by noting that the mechanisms which drive gas inwards in disk galaxies are generally inefficient at removing angular momentum, leading to stalled inflows. Thus, a tiered series of such processes is required to bring gas to the smallest scales, each of which on its own may not correlate with the presence of an AGN. Similarly, each may be associated with a starburst event, making it important to discriminate between 'circumnuclear' and 'nuclear' star formation. In this contribution, we show that stellar feedback on scales of tens of parsecs plays a critical role in first hindering and then helping accretion. We argue that it is only after the initial turbulent phases of a starburst that gas from slow stellar winds can accrete efficiently to smaller scales. This would imply that the properties of the obscuring torus are directly coupled to star formation and that the torus must be a complex dynamical entity. We finish by remarking on other contexts where similar processes appear to be at work.
description: to appear in 'The central kiloparsec in Galactic Nuclei', Journal of Physics: Conference Series (JPCS), IOP Publishing
Speaking Thier Language: A Randomized Pilot Study of Synchronous Online Chat Groups for Young Adults with Cancer
Creators: name: Lang, Michael
Publisher: name: Graduate Studies
Year: 2015
Subjects: subject: Mental Health
subject: Oncology
subject: Psychology--Clinical
subject: Young Adults
subject: Psychosocial Oncology
subject: cancer
subject: Online Intervention
subject: Randomized Trial
subject: Pilot Study

description: Background: In Canada, over 7,000 adolescents and young adults or “AYA” (ages 18 to 39 years) are diagnosed with cancer annually. Few evidence-based psychosocial interventions exist for this population. Methods: We conducted a randomized pilot study to compare a new AYA-specific psychotherapy model to a standard psycho-educational model, using CancerChatCanada (CCC) synchronous online chat groups. Results: 34 AYAs in Alberta participated in the study and all feasibility targets were met. Participants rated the new AYA model more suitable and it appeared to improve important group processes and psychosocial outcomes. A power calculation providing sample size estimation for an RCT indicated that more than 90 participants would be needed to demonstrate differential efficacy between groups. Discussion: This randomized study design is feasible with some important modifications. Conclusion: Online synchronous chat groups can be used to provide psychosocial care for AYAs. Future RCTs could provide evidence of efficacy for age-specific psychotherapy models.
Disaster resilience, vulnerability and adaptive capacity of street children in Manila
Creators: name: Higgs, Shelby Louise
Publisher: name: The Australian National University
Year: 2017
Subjects: street children
Manila
Philippines
natural disaster
resilience
adaptive capacity
transformation
vulnerability
ethical research of children
demography
social capital
cognitive social capital

description: This thesis investigates the resilience of street children in Manila, the Philippines, who are exposed to multiple natural disasters. Despite their longstanding presence and high visibility in urban areas, street children have attracted little scholarly attention. However, a surge of interest in the global street child phenomenon spurred by the 1989 United Nations Convention on the Rights of the Child seeks to produce more nuanced contextual analysis of the social, economic and political processes that affect the demography of street children in a specific geographic area. Despite such efforts, the street child discourse continues to be dominated by contrasting, and at times competing, government and civil society interests, while academic inquiry remains stifled by typological, methodological and ethical dilemmas. The following study contributes to addressing that void by exploring these research challenges and investigating them with a mixed method examination of street children and their health, education and resilience in Manila, the Philippines. While most academic inquiry has been limited to investigating the children’s vulnerability, this study applies a strengths-based, adaptive capacity framework to examine the resilience of Manila’s street children in spite of the multiple stressors of street life and frequent natural disasters. Manila, home to an estimated 50,000 street children, is prone to frequent natural hazards including floods, typhoons, and landslides. Disaster vulnerability in Manila is exacerbated by political corruption and socio-economic inequalities, which provide a particularly dynamic lens through which to examine the influence of governance and civil society on the adaptive capacity of this population. While adaptive capacity is generally studied at a systems scale, this research explores how street children's adaptive capacity may vary spatially by the resources available to them and their cognitive social capital, defined here as their perceptions of trust and belonging to a community. In addition to the exploration of the children’s adaptive capacity, this study seeks to identify and analyse current strategies, methodologies, and gaps in the research on street children to provide guidance for future studies. Understanding and fostering the capacity of this highly adaptive population of street children may prove invaluable to generating the larger scale transformations necessary for residents of Manila to better adapt to natural disasters and other stressors in the future.
Direct Integration of the Collisionless Boltzmann Equation in Six-dimensional Phase Space: Self-gravitating Systems
Creators: name: Yoshikawa, Kohji
name: Yoshida, Naoki
name: Umemura, Masayuki
Publisher: name: arXiv
Year: 2012
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: We present a scheme for numerical simulations of collisionless self-gravitating systems which directly integrates the Vlasov--Poisson equations in six-dimensional phase space. By the results from a suite of large-scale numerical simulations, we demonstrate that the present scheme can simulate collisionless self-gravitating systems properly. The integration scheme is based on the positive flux conservation method recently developed in plasma physics. We test the accuracy of our code by performing several test calculations including the stability of King spheres, the gravitational instability and the Landau damping. We show that the mass and the energy are accurately conserved for all the test cases we study. The results are in good agreement with linear theory predictions and/or analytic solutions. The distribution function keeps the property of positivity and remains non-oscillatory. The largest simulations are run on 64^6 grids. The computation speed scales well with the number of processors, and thus our code performs efficiently on massively parallel supercomputers.
description: 35 pages, 19 figures. Submitted to the Astrophysical Journal
Interfaces of Modulation: The Shaping of a Passenger-Customer in Japanese Urban Railway Spaces
Creators: name: Negishi, Kaima
Publisher: name: The Australian National University
Year: 2016
Subjects: control
security
affect
railway
service-oriented economy

description: This thesis explores the mechanism of ‘soft’ control in relation to the contemporary service-oriented economy to better understand how passengers in urban railway spaces come to not just accept control but also eventually become agents of control. This thesis critically examines the governing mechanism of passenger mobilities in the context of Japanese urban railway spaces. Building on the existing literature around security, mobilities and the body, this thesis situates urban railway spaces as an important site of containment where passengers’ bodies become a vital interface to circulate a desire for security and maintain networked circuits of control. In the networked circuits of control, passengers are not just subject to control, but also become participants in security operations as they are transformed from the subordinates into the enforcers to modulate each other’s behaviours. Significantly, the contemporary mechanism of control takes a ‘soft’ approach to prompt individual passengers to become participants of the operation. While the existing literature has tended to downplay the prevalence of ‘soft’ control, this thesis argues that such softness plays a pivotal role in effectively conscripting passengers to turn themselves from a passive object into an active agent of control. In the process, passengers’ bodies become the key vector through which passengers are brought into a networked circuit of control, mediate relations with authorities and create a strong impetus to actively take part in securitization, bringing others in to participate, uphold and reinforce security operations. This thesis examines how the forceful mechanism of soft control effectively turns individuals into willing participants in supporting the system of securitization. By using descriptive methods and drawing upon auto-ethnographic accounts, focused interviews and textual analyses, this thesis demonstrates how passengers’ bodies are enrolled into a desire for orderliness in urban railway spaces such that they attempt to reinforce the securitization of orderly operation and containment of unexpected disruption. However, these developments need to be discussed in relation to the rise of the service-oriented economy as security operations are today increasingly becoming a fundamental part of service provision for urban railway operators. The vital function of services provided by urban railway operators today is not only to accommodate but also to manipulate passengers’ desires to take hold of their bodies and turn them into ‘orderly’ subjects. The thesis identifies some of the effects that the rise of the service-oriented economy has on security operations and offers an alternative reading of ‘orderliness’ in Japanese urban railway spaces where passengers have effectively become passenger-customers.
Confinement and correlation effects in the Xe@C60 generalized oscillator strengths
Creators: name: Amusia, M. Ya.
name: Chernysheva, L. V.
name: Dolmatov, V. K.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: The impact of both confinement and electron correlation on generalized oscillator strengths (GOS's) of endohedral atoms, A@C60, is theoretically studied choosing the Xe@C60 4d, 5s, and 5p fast electron impact ionization as the case study. Calculations are performed in the transferred to the atom energy region beyond the 4d threshold, omega = 75--175 eV. The calculation methodology combines the plane wave Born approximation, Hartree-Fock approximation, and random phase approximation with exchange in the presence of the C60 confinement. The confinement is modeled by a spherical delta-function-like potential as well as by a square well potential to evaluate the effect of the finite thickness of the C60 cage on the Xe@C60 GOS's. Dramatic distortion of the 4d, 5p, and 5s GOS's by the confinement is demonstrated, compared to the free atom. Considerable contributions of multipolar transitions beyond dipole transitions in the calculated GOS's is revealed, in some instances. The vitality of accounting for electron correlation in calculation of the Xe@C60 5s and 5p GOS's is shown.
description: 7 pages, 3 figures, submitted to Physical Review A
Scaling Up [to] a Population Health Intervention: A Readiness Assessment Framework
Creators: name: Nguyen, Duyen Thi Kim
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Public Health
subject: scaling up
subject: Scale Up
subject: population health
subject: Public Health
subject: intervention
subject: program
subject: Health

description: Background: Attempts to scale up a population health intervention (PHI) have achieved variable success, which, in part, is attributable to limited knowledge of scale up and lack of systematic guidance to support successful scale up. The concept of readiness is underrepresented in scale up and its consideration may improve the likelihood of success. Objective: To develop and assess a conceptual framework focused on the successful scale up of a PHI, which may be employed to gauge a PHI’s readiness for scale up success. Theoretical framework: This study integrated diffusion of innovations, organizational readiness for change, and complex adaptive systems theories. Methods and Results: The Scale Up Readiness Assessment Framework was developed and refined through a primarily qualitative methods design with three complementary studies, which were informed by the theoretical and empirical literature. Study one used a critical interpretive synthesis of the literature to develop the Framework. The synthesis identified 11 important actions in the successful scale up of a PHI, which were organized into three phases: Groundwork, Implementation, and Sustainment. Key components and hallmarks of a successful scale up approach were also determined. Study two used a modified Delphi method to assess content and face validity of the Framework’s actions and phases. A panel of PHI and scale up experts agreed all phases and actions were important; the Groundwork phase and six actions were representative of a successful scale up; and all were logically presented. Experts’ assessments guided the Framework’s second version. Study three involved pilot tests with potential users of the Framework (version 2.0), who commented how the Framework’s utility, value, and face validity might apply to their PHI. Participants concluded the Framework was informative, offered valuable guidance, and may serve multiple purposes beyond readiness assessment. Pilot feedback led to a final Framework revision (version 3.0). Conclusion: This research provides important conceptual advancements and insights regarding the practice of successful scale up. The research produced a usable product, the Framework, which may be used by academic and government PHI stakeholders for scale up readiness assessment and planning. Learnings from this framework have potentially diverse applications beyond its initial intended purpose.
Additional file 1 of Size matters: the impact of nucleus size on results from spatial transcriptomics
Creators: name: Mohammadi, Elyas
name: Chojnowska, Katarzyna
name: Bieńkowski, Michał
name: Kostecka, Anna
name: Koczkowska, Magdalena
name: Żmijewski, Michał A.
name: Jąkalski, Marcin
name: Ingelsson, Martin
name: Filipowicz, Natalia
name: Olszewski, Paweł
name: Davies, Hanna
name: Wierzbicka, Justyna M.
name: Hyman, Bradley T.
name: Dumanski, Jan P.
name: Piotrowski, Arkadiusz
name: Mieczkowski, Jakub
Publisher: name: figshare
Year: 2023
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Plant Biology

description: Additional file 1: Figure S1. Improvement of the spot clustering through CSDI. The colors represent the results of unsupervised clustering performed either before (A) or after (B) application of CSDI. (A) The expected consistency of the pattern of spot clusters between consecutive slices is missed. (B) The consistency of clustering after consecutive slices data integration is improved. The patients IDs are marked above the pictures. The designations “before” and “after” refer to pictures made either before or after CSDI respectively.
Studies in Natural Products Synthesis
Creators: name: Kim, Hye Sun
Publisher: name: The Australian National University
Year: 2016
Subjects: Amaryllidaceae Alkaloids
Total Syntheses
Pyrrolophenanthridinone
Lycoranine A
Lycoranine B
2-Methoxypratosine
Lycosinine A
Lycosinine B
Lycosprenine
Pleurospiroketal A

description: The pyrrolophenanthridinone-containing Amaryllidaceae alkaloids, representative examples of which include hippadine, lycoranine A, lycoranine B and 2-methoxypratosine, often display a wide range of biological activities that are attributed to its core structure. As such, studies on their syntheses have been pursued by a number of research groups. The opening chapter of this thesis provides general introduction to the pyrrolophenanthridinone-containing natural products and previous synthetic studies in the area. The research work presented in Chapter Two describes the first total syntheses of three pyrrolophenanthridinone-containing Amaryllidaceae alkaloids, namely lycoranine A, lycoranine B and 2-methoxypratosine, using two related synthetic pathways that only differ in the polarity of the intermediates involved in pivotal Suzuki-Miyaura cross-coupling reactions. The superior one involved iridium-catalysed C–H borylation of the appropriate indoles to generate 7-borylindoles and the Suzuki-Miyaura cross-coupling of these with the relevant bromobenzoate. Based on the aforementioned successes in using iridium-catalysed C–H borylations of indoles during natural product synthesis, studies on such processes were extended to indolines. Specifically, then, Chapter Three details the work carried out on the iridium-catalysed C–H borylation of various indolines, as well as synthetic approaches to the indoline-containing natural products, lycosinine A, lycosinine B and lycosprenine. The synthesis of lycosinine A was completed over three steps that involve an iridium-catalysed C–H borylation reaction, a Suzuki-Miyaura cross-coupling reaction and a reductive methylation process. The work presented in Chapter Four details the author’s studies on the preparation of propargyl ether, a potential substrate for participation in a palladium-catalysed intramolecular Alde-ene (IMAE) reaction leading to the hexahydrobenzofuran that embodies key structural features associated with the natural product pleurospiroketal A. The final Chapter (Five) presents all of the experimental procedures and data associated with the compounds prepared during the course of the research work presented in this thesis.
Roosting Behaviour and Thermoregulation of the Northern Long-Eared Bat (Myotis septentrionalis) Near the Northern Extent of its Range
Creators: name: Kaupas, Laura
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Animal Physiology
subject: Ecology
subject: FOS: Biological sciences
subject: Roost Ecology
subject: Thermoregulation
subject: Bats

description: Reproductive female mammals have high energetic demands. This may be particularly true for small, nocturnal mammals at high latitudes, where temperatures are relatively low and summer nights are short. Tree roosts are colder than building roosts, likely resulting in greater energetic constraints for tree-roosting bats. My research goal was to determine how reproductive, tree-roosting Myotis septentrionalis reduce the costs of roosting in relatively cool roosts near the northern extent of their range. I investigated the roosting behaviour of M. septentrionalis, and the thermoregulatory patterns and reproductive timing of M. septentrionalis and building-roosting M. lucifugus in the Northwest Territories, Canada. Myotis septentrionalis exhibited roosting behaviours that should reduce energetic costs. Despite lower tree-roost temperatures, the two species used similar thermoregulatory patterns, suggesting higher energetic costs for M. septentrionalis. However, M. septentrionalis foraged for longer, perhaps compensating for these higher costs, resulting in similar reproductive timing and rates between species.
On SDE associated with continuous-state branching processes conditioned to never be extinct
Creators: name: Fittipaldi, M. C.
name: Fontbona, J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60J80, 60H20, 60H10

description: We study the pathwise description of a (sub-)critical continuous-state branching process (CSBP) conditioned to be never extinct, as the solution to a stochastic differential equation driven by Brownian motion and Poisson point measures. The interest of our approach, which relies on applying Girsanov theorem on the SDE that describes the unconditioned CSBP, is that it points out an explicit mechanism to build the immigration term appearing in the conditioned process, by randomly selecting jumps of the original one. These techniques should also be useful to represent more general h-transforms of diffusion-jump processes.
Additional file 2 of Size matters: the impact of nucleus size on results from spatial transcriptomics
Creators: name: Mohammadi, Elyas
name: Chojnowska, Katarzyna
name: Bieńkowski, Michał
name: Kostecka, Anna
name: Koczkowska, Magdalena
name: Żmijewski, Michał A.
name: Jąkalski, Marcin
name: Ingelsson, Martin
name: Filipowicz, Natalia
name: Olszewski, Paweł
name: Davies, Hanna
name: Wierzbicka, Justyna M.
name: Hyman, Bradley T.
name: Dumanski, Jan P.
name: Piotrowski, Arkadiusz
name: Mieczkowski, Jakub
Publisher: name: figshare
Year: 2023
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Plant Biology

description: Additional file 2: Figure S2. Improvement of the label transferring by CSDI. The annotation probability is shown as a scheme for three different cell types. Label transferring from snRNA-seq to ST consecutive slices is shown before and after data integration. Before Integration: the probability of spot annotations for neurons is not compatible with tissue histology. After integration: the probability of the presence of neurons increased in the GM of the cerebral cortex.
Decision Support for Strategic and Operational Planning of Logistic Services
Creators: name: Livani, Emadoddin
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Computer Science
subject: Decision Support Systems
subject: Waste and Recycling Management
subject: Machine Learning
subject: Bayesian Networks
subject: Vehicle Routing
subject: Genetic Algorithms
subject: Optimization

description: Logistics services are type of services that deal with industries like manufacturers, raw material suppliers, distributors, retailers, and shippers within the supply chain. Strategic planning for logistic services is a complex process that requires an understanding of how the different elements and activities of logistics. The decision-making process is considered as fundamental to strategic planning. The majority of the current studies focus only on optimizing the operational resources or model the strategic decisions without evaluating their impact on the operational resources. A decision support methodology, named SOPLS, is proposed in this thesis for Strategic and Operational Planning of Logistic Services. SOPLS consists of two layers: strategic and operational. The methods are integrated to form the strategic layer: model-based scenario analysis, search-based scenario generation, and multi-criteria scenario prioritization. The model-based scenario analysis works based on Bayesian belief networks (BBN) to provide decision support for cost-benefit analysis of the service scenarios. The search-based scenario generation method integrates BBN with genetic algorithms in order to generate new scenarios based on a given goal. A multi-criteria scenario prioritization method is proposed, by integrating BBN with analytical hierarchy process, to automatically prioritize the scenarios based on user preferences. Two methods are integrated in the operational layer. Firstly, a hybrid prediction method is proposed for estimating the demand by integrating k-means clustering with linear regression. Secondly, a vehicle routing algorithm is proposed to minimize the length of the routes, taken by the service vehicles. By integrating the strategic and operational levels, the impact of the strategic decisions on the operational resources, like staff and vehicles, will be estimated. The results will potentially trigger updating the strategies, or even the parameters in the cost-benefit model, which form an iterative decision making process. We evaluated the proposed decision support methodology through a collaboration project with the City of Calgary’s Waste and Recycling Services (WRS). The results showed the usefulness and applicability of the proposed solution in the area of waste management.
Evangelism for Democracy and Social Engineering: The Origins of Social Studies Curriculum in Alberta, 1919-1935
Creators: name: Wouts, Adrian
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Education--History of
subject: history of education

description: Cooperation was the animating feature of the United Famers and Farm Women of Alberta (UFA/UFWA) and was reflected in their reform initiatives during their tenure in the Alberta Legislature between 1921 and 1935. It was the United Farmers and Farm Women of Alberta who instigated the reform of grade school curriculum leading to the shift from history to social studies beginning in 1935. With the advent of social studies in Alberta, gone was a study of the past; social studies worked to establish a democratic and cooperative society in the future. It is the objective of this thesis to contextualize the shift from history to social studies curriculum by considering the cooperative ethos expounded by the UFA/UFWA in Alberta between 1919 and 1935. At the same time, my objective in this thesis is to expand the understanding of the origins of social studies beyond a widely held view among some historians that it was brought to Alberta from the United States by a select group of educational elites. This narrow perspective ignores the local roots of this momentous curriculum development. The shift from history to social studies took place amidst a rising tide of prairie populism sweeping Alberta during the first three decades of the twentieth century. During these decades, UFWA leaders, rural women school teachers, and their interactions with an emerging educational bureaucracy in Alberta contributed significantly to the emergence of social studies. The onset of social studies involved a wider cast of characters and local movements than has been accounted for to date.
Generosity, third party punishment & theory of mind among ni-Vanuatu children
Creators: name: Dixson, Henry George Wainhouse
Publisher: name: The Australian National University
Year: 2016
Subjects: Theory of mind
third party punishment
generosity
altruism
cooperation
ontogeny
child development
Vanuatu
Melanesia
behaviour
behavior
culture
cultural

description: Humans are a highly cooperative species, rivalled only by eusocial insects. There is also considerable diversity in the scale and forms that human cooperation takes. Investigating how certain cooperative capacities emerge in development and interact with particular environments provides deeper insights into the ontogenetic roots of our potential for large-scale cooperation. Behavioural economic games can measure generosity and the punishment of noncooperators in ephemeral and anonymous interactions. Although data has already been gathered from diverse populations including small-scale societies, few studies have gathered similar data from children. This project focuses on the children of the Melanesian Island nation of Vanuatu as its primary subject. Furthermore, it uniquely splits its focus between pikinini lo vilej (rural children from ‘the village’) and pikinini lo taon (‘urban’ children from the town). Using a combination of methods derived from behavioural economics, developmental psychology, and cultural anthropology, this research project investigates the emergence of generosity, ‘altruistic punishment’ (henceforth third party punishment), and theory of mind among ni-Vanuatu children. Research in developing countries such as Vanuatu need to focus more on differences not between ‘Western vs. non-Western’, but those occurring within the same general society between urban and rural contexts, which may influence very different pathways to social, behavioural, and even cognitive development. The urban/rural, town/village divide is not one that has been imposed by the researcher; it is a salient component of a ni-Vanuatu sense of place and a strong feature of local ideological narratives. This research project presents unique findings of large differences between urban and rural ni-Vanuatu children in important social, behavioural and cognitive domains. It underscores the importance of utilising not only multiple measures of capacities that undergird our cooperative nature, but of applying these equally between urban and rural non-Western populations in order that we might better understand how these environments shape different cooperative phenotypes necessary for different scales of cooperation.
Additional file 3 of Size matters: the impact of nucleus size on results from spatial transcriptomics
Creators: name: Mohammadi, Elyas
name: Chojnowska, Katarzyna
name: Bieńkowski, Michał
name: Kostecka, Anna
name: Koczkowska, Magdalena
name: Żmijewski, Michał A.
name: Jąkalski, Marcin
name: Ingelsson, Martin
name: Filipowicz, Natalia
name: Olszewski, Paweł
name: Davies, Hanna
name: Wierzbicka, Justyna M.
name: Hyman, Bradley T.
name: Dumanski, Jan P.
name: Piotrowski, Arkadiusz
name: Mieczkowski, Jakub
Publisher: name: figshare
Year: 2023
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Plant Biology

description: Additional file 3: Figure S3. A comparison between the pattern of spot classification after CSDI through spot clustering and label transferring methods. The consistency between the results from these two methods, which is compatible with the histological information of tissue slices, supports the accuracy of the spot categorization.
Neutrino nucleus reactions at high energies within the GiBUU model
Creators: name: Lalakulich, O.
name: Gallmeister, K.
name: Leitner, T.
name: Mosel, U.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The GiBUU model, which implements all reaction channels relevant at medium neutrino energy, is used to investigate the neutrino and antineutrino scattering on iron. Results for integrated cross sections are compared with NOMAD and MINOS data. It is shown, that final state interaction can noticeably change the spectra of the outgoing hadrons. Predictions for the Miner$ν$a experiment are made for pion spectra, averaged over NuMI neutrino and antineutrino fluxes.
description: Talk at NuInt11, Dehradun, India, March 2011
Subjective social status and its associations with social vulnerabilities and health
Creators: name: Tang, Karen
Publisher: name: Graduate Studies
Year: 2017
Subjects: subject: Epidemiology
subject: Public Health
subject: Health Services Research
subject: Health care access
subject: Social status

description: BACKGROUND: Subjective social status (SSS) is the perception of where one stands in a social hierarchy, distinct from one’s actual, objective position in this hierarchy. SSS may influence health through behavioral and psychosocial mechanisms. METHODS: We conducted three sub-studies to examine whether SSS affects risk of and outcomes in chronic disease, and to explore the role of health care access and experience of social vulnerabilities in the SSS-health pathway. RESULTS: We found that low SSS is associated with increased risk of 1) cardiovascular disease; 2) hospital readmissions and barriers to health care access; and 3) social vulnerabilities that affect health care access. Having high perceived status in the community appears to mitigate the experience of social vulnerabilities through the ability to mobilize social supports. CONCLUSION: Subjective social status has important associations with health and clinical outcomes. These findings have implications to the development of interventions that aim to reduce disparities.
Mechanical lattice instability and thermodynamical properties in classical solids
Creators: name: Rastelli, G.
name: Cappelluti, E.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: In this paper we revisit the onset of the instability of the solid state in classical systems within self-consistent phonon theory (SCPT). Spanning the whole phase diagram versus volume and versus pressure, we identify two different kinds of mechanism: one mainly relevant at constant volume, associated with the vanishing of the SCPT solution; and one related to the disappearing at a spinodal temperature of the solid phase as a metastable energy minimum. We show how the first mechanism occurs at extremely high temperatures and it is not reflected in any singular behavior of the thermodynamical properties. In contrast, the second one appears at physical temperatures which correlate well with the melting temperature and it is signalized by the divergence of the thermal compressibility as well as of the the lattice expansion coefficient.
description: (submitted to PRB)