cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Inhaler technique mastery and maintenance in healthcare professionals trained on different devices
Creators: name: Sinthia Bosnic-Anticevich
name: Callan, Christina
name: Chrystyn, Henry
name: Lavorini, Federico
name: Nikolaou, Vasilis
name: Kritikos, Vicky
name: P. N. Richard Dekhuijzen
name: Roche, Nicolas
name: Bjermer, Leif
name: Rand, Cynthia
name: Zwar, Nicholas
name: Price, David B.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Objective: Healthcare professionals (HCPs) are required to assess and train patients in the correct use of inhalers but are often unable to demonstrate correct technique themselves. We sought to assess the level of training required for HCPs to master and maintain device mastery when using two different dry powder inhalers (DPIs). Methods: We conducted a randomized, un-blinded, crossover study in undergraduate HCPs who undertook a six-step training procedure (intuitive use, patient information leaflet, instructional video, individual tuition from expert, then two repeats of individual tuition) for the use of Turbuhaler® (an established device) and Spiromax® (a newer device, reportedly easier to use). Device mastery (absence of errors) was evaluated by expert assessors at each training step. Maintenance of mastery was assessed 4 ± 1 week (visit 2) and 8 ± 2 weeks (visit 3) after initial training (visit 1). Results: Of 516 eligible participants, 113 (22%) demonstrated device mastery prior to training on Spiromax® compared with 20 (4%) on Turbuhaler® (p < 0.001). The median number of training steps required to achieve mastery was 2 (interquartile range [IQR] 2–4) for Spiromax® and 3 (IQR 2–4) for Turbuhaler® (p < 0.001). A higher number of participants maintained mastery with Spiromax® compared with Turbuhaler®, at visits 2 and 3 (64% vs 41% and 79% vs 65%, respectively; p < 0.001). Conclusions: There are significant differences in the nature and extent of training required to achieve and maintain mastery for Spiromax® and Turbuhaler® devices. The implications on clinical practice, device education delivery, and patient outcomes require further evaluation.
title: PFC: Enquête Vendée
Creators: name: Modèles, Dynamiques
name: Laks, Bernard
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2011
Subjects: subject: Français
subject: fra
subject: Les enfants de l'enquêtée, son enfance, son travail, ses loisirs depuis la retraite.
subject: phonologie du français
subject: Dialecte de Centre
subject: phonetics
subject: phonology
subject: text_and_corpus_linguistics

description: Annotation du fichier de transcription PRAAT de la conversation libre
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Synthesis of novel pyrimidine derivatives with (pyridin-3-ylmethyl)thio and phenylamino moieties and evaluation of their antifungal activity
Creators: name: Wang, Shi-Chun
name: Gao, Ji-Gang
name: Zhang, Shuai
name: Liu, Si
name: Jiang, Lin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Cancer
subject: Plant Biology
subject: Virology

description: A series of novel pyrimidine derivatives with (pyridin-3-ylmethyl)thio and phenylamino moieties were synthesized from ethyl acetoacetate, thiourea, 3-pyridinylmethyl chloride hydrochloride, and substituted anilines by multi-step reactions. The structures of the target compounds were characterized by IR, 1H NMR, 13C NMR and elemental analysis. The in vitro antifungal activities against Botrytis cinerea and Sclerotinia sclerotiorum were evaluated. The result showed that N-phenyl-6-methyl-2- ((pyridin-3-ylmethyl)thio) pyrimidin-4-amine (4a) displayed high inhibition activity against Botrytis cinerea with 87.5%inhibition at 100 µg/mL; 4a, and N-(4-isopropylphenyl)-6-methyl-2-((pyridin-3-ylmethyl)thio)pyrimidin-4-amine (4c), N-(4-methoxyphenyl)-6-methyl-2-((pyridin-3-ylmethyl)thio)pyrimidin-4-amine (4d) and N-(2-hydroxy-5-chloro)-6-methyl-2-((pyridin-3-ylmethyl)thio)pyrimidin- 4-amine (4h) exhibited sufficient activities against Sclerotinia sclerotiorum with 86.6% –93.7% inhibitions at the same concentration.
title: PFC: Enquête Roanne
Creators: name: Modèles, Dynamiques
name: Laks, Bernard
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2011
Subjects: subject: Français
subject: fra
subject: Formel: vie professionnelle Informelle: problèmes dans la vie professionnelle
subject: phonologie du français
subject: Dialecte de Rhône Alpes
subject: phonetics
subject: phonology
subject: text_and_corpus_linguistics

description: Annotation du fichier de transcription PRAAT de la conversation libre
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
MPEC 2025-J05 : DAILY ORBIT UPDATE (2025 May 1)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2025
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Supplementary Material for: Micronutrients, Essential Fatty Acids and Bone Health in Phenylketonuria
Creators: name: Demirdas, S.
name: Van Spronsen, F.J.
name: Hollak C.E.M.
name: Van Der Lee, J.H.
name: Bisschop, P.H.
name: Vaz, F.M.
name: Ter Horst, N.M.
name: Rubio-Gozalbo, M.E.
name: Bosch, A.M.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Introduction: In phenylketonuria (PKU), a natural protein-restricted dietary treatment prevents severe cognitive impairment. Nutrient deficiencies may occur due to strict diet. This study is aimed at evaluating the dietary intake and blood concentrations of micronutrients and essential fatty acids (FA), bone mineral density (BMD) and fracture history in patients on long-term dietary treatment. Methods: Sixty early diagnosed Dutch patients (aged 1-39 years) were included in a multi-center cross-sectional study. Their dietary intake, blood concentrations of micronutrients, FA, fracture history and BMD were assessed. Results: Selenium dietary intake and serum concentrations were low in 14 and 46% of patients, respectively. The serum 25-OH vitamin D2 + D3 concentration was low in 14% of patients while 20% of patients had a low vitamin D intake. Zinc serum concentrations were below normal in 14% of patients, despite adequate intake. Folic acid serum concentrations and intake were elevated. Despite safe total protein and fat intake, arginine plasma concentrations and erythrocyte eicosapentaenoic acid were below reference values in 19 and 6% of patients, respectively. Low BMD (Z-score Conclusions: Dutch patients with PKU on long-term dietary treatment have a near normal nutrient status. Supplementation of micronutrients of which deficiency may be deleterious (e.g., vitamin D and selenium) should be considered. BMD warrants further investigation.
Supplementary Material for: Potassium-Channel-Independent Relaxing Influence of Adipose Tissue on Mouse Carotid Artery
Creators: name: Laskowski, M.
name: Andersson, C.
name: Eliasson, E.
name: Golubinskaya, V.
name: Nilsson, H.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Since the cardiovascular consequences of obesity reportedly vary in different types of obesity, we investigated the influence of adipose tissue from different locales on the phenylephrine-induced tone of the mouse carotid artery. Vessels were mounted in a Mulvany-Halpern-type wire myograph, and adipose tissue, from the back (brown) or mesenteric or inguinal subcutaneous (white), was placed around the artery. Contractile responses to phenylephrine were not affected by brown adipose tissue but were reduced (p < 0.001) by either type of white adipose tissue, with no difference between the 2 locales. The relaxing effect persisted in the presence of the Kv7 channel inhibitor XE991 (10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone), the KATP channel inhibitor glibenclamide (1 µM), or the KV channel inhibitor 4-amino pyridine (1 mM), as well as after elevation of the extracellular potassium concentration to 30 mM. Contractions of rat carotid artery were equally reduced by mouse and rat subcutaneous adipose tissue. Thus, white, but not brown, adipose tissue reduces the adrenergic contractions of the carotid artery with no differences between the locales of origin, and the effect appears largely independent of potassium channels.
Contrasting bio-optical characteristics of coastal water prior to and in the aftermath of a tropical super cyclone
Creators: name: Sudarsana Rao Pandi
name: Chiranjeevulu Gundala
name: Rayaprolu, Kiran
name: Naroju, Veera Harikrishnachari
name: Muralikrishna Rallabhandi
name: Srinivasarao Balivada
name: Lotliker, Aneesh A.
name: Nittala S. Sarma
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Sociology
subject: FOS: Sociology

description: Apparent and inherent optical properties were measured in the coastal region off Visakhapatnam (Bay of Bengal) during pre-monsoon season (January–May) of successive years, in-between of which the (October 2014) Hudhud super cyclone had landfall across. For 5 months after the cyclone in the region up to 50 m isobath, or 15 km from the coast and 6 months after the cyclone in the region up to 30 m isobath, or 5 km away, the particle back-scattering coefficient (bbp) and remote-sensing reflectance (Rrs) were anomalously higher throughout the spectral region (400–700 nm) than during other times. The bbp spectral slope coefficient γ is abnormally higher than predicted from the bbp(680)–γ model relationship, and Rrs(685) is also abnormally higher than the significant Rrs(685)–chlorophyll-a (chl-a) relationship would predict. These exceptional properties are attributed to the presence of little absorbing and highly reflecting sub-micrometre-sized particles in fine suspension that leached from the coastal deposits emplaced in the study region from the nearby harbour during the cyclone. The optical properties recovered subsequently. In the period when the reflectance and scattering spectra are not recovered, the Rrs(685) is no longer a proxy of chl-a. Remote-sensing algorithms for phytoplankton abundance of the coastal region during this period need correction.
A Transition Metal-Free Direct Nucleophilic α -substitution of Morita-Baylis-Hillman Alcohols with Amines and Thiols
Creators: name: Oueslati, Yosra
name: Baioui, Narjes
name: Farhat Rezgui
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: An efficient transition metal-free allylic nucleophilic α-substitution of Morita-Baylis-Hillman alcohols with both aliphatic and aromatic amines in refluxing toluene, using activated molecular sieves as additives, is described herein. The reaction proceeded with exclusive α-regioselectivity in moderate to excellent yields with the formation of water as the sole byproduct. Under the same conditions, upon treatment of some thiols with the title substrates, allylic sulfides were obtained in excellent yields and high regioselectivity.
Microwave-Assisted Synthesis and Crystal Structure of Some Novel 1,2,4-Oxadiazol-5-Ylmethyl-1,2,3-Triazoles
Creators: name: Yaşar Dürüst
name: Karakuş, Hamza
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: 60506 Virology

description: Microwave-assisted 1,3-dipolar cycloaddition of 5-azidomethyl 3-aryl substituted 1,2,4-oxadiazoles to electron deficient alkyne; phenyl propiolic acid affords a series of 1,2,3-triazole derivatives carrying 3-p-substitutedphenyl-1,2,4-oxadiazolyl methyl unit. The structures of all the cycloadducts were elucidated by means of IR, NMR (1H, 13C, 2D), MASS (low and high resolution) spectra, X-Ray diffraction data and physical characteristics (melting points and Rf values).
Sorption performance of light rare earth elements using zirconium titanate and polyacrylonitrile zirconium titanate ion exchangers
Creators: name: M. Khalil
name: Y. F. El-Aryan
name: E. M. El Afifi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Plant Biology
subject: FOS: Biological sciences

description: Lanthanum, cerium, neodymium, and samarium were sorption from aqueous solutions using zirconium titanate (ZrTi) and polyacrylonitrile zirconium titanate (PANZrTi) ion exchangers. The characterizations of prepared materials were performed using XRD, SEM, FTIR, TGA, and DTA techniques. The sorption behavior of various ions toward synthesized resin has been studied depending on reaction temperatures, pH values, and initial concentrations. The selectivity order found is Sm3+ > Nd3+ > Ce3+ > La3+ on ZrTi-100, Ce3+ > Sm3+ ≈ Nd3+ > La3+ on ZrTi-150, and Sm3+ ≈ Ce3+ > Nd3+ > La3+ on PANZrTi depending on the condition of prepared ZrTi samples. The Kd for lanthanide ions was slightly decreased with temperature increased, which indicated the exothermic nature. The sorption data obtained for equilibrium conditions have been analyzed using the different isotherm models, and the applicability of these isotherm equations was compared by the correlation coefficients, R2. It was established that the equilibrium isotherm models’ applicability follows the order: Langmuir > Dubinin– Radushkevich > Freundlich. It is found the Ce3+ has high adsorption capacity on each of ZrTi-100 and ZrTi-150, while Nd3+ has high adsorption capacity on PANZrTi.
The initial stages of multicomponent particle formation during the gas phase combustion synthesis of mixed SiO2/TiO2
Creators: name: Fang, Jiaxi
name: Wang, Yang
name: Kangasluoma, Juha
name: Attoui, Michel
name: Junninen, Heikki
name: Kulmala, Markku
name: Petäjä, Tuukka
name: Biswas, Pratim
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The ability to properly scale the synthesis of advanced materials through combustion synthesis routes is limited by our lack of knowledge regarding the initial stages of particle formation. In flame aerosol reactors, the high temperatures, fast reaction rates, and flame chemistry can all play a critical role in determining the properties of the resulting nanomaterials. In particular, multicomponent systems pose a unique challenge as most studies rely on empirical approaches toward designing advanced composite materials. The lack of predictive capabilities can be attributed to a lack of data on particle inception and growth below 2 nm. Measurements for the initial stages of particle formation during the combustion synthesis of SiO2 and composite SiO2/TiO2 using an atmospheric pressure inlet time-of-flight mass spectrometer are presented. Both positively and negatively charged clusters can be measured and results show the presence of silicic acid species which grow through dehydration, hydrogen abstraction, and interactions with hydroxyl radicals. In the case of composite SiO2/TiO2 particle formation, new molecular species containing Ti atoms emerge. Tandem differential mobility analysis-mass spectrometry (DMA-MS) provided further insight into the size-resolved chemistry of particle formation to reveal that at each cluster size, further hydroxyl-driven reactions take place. From this we can conclude that previous assumptions on collisional growth from simple monomer species of SiO2 and TiO2 do not sufficiently describe the collisional growth mechanisms for particle growth below 2 nm. Copyright © 2018 American Association for Aerosol Research
Numerical analysis of the dynamics of aerosol inertial collection and aggregation on raindrops
Creators: name: Zhu, Hui
name: Hua, Fengjiao
name: Kang, Yanming
name: Chen, Yonghang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Physical Sciences not elsewhere classified
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Astronomical and Space Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: A three-dimensional stochastic model is developed for predicting atmospheric aerosol collection and aggregation on the surface of a falling raindrop at its terminal velocity. Potential flow and viscous flow are assumed as the flow fields in the vicinity of the large and the small raindrops, respectively. The results show that hydrophobic coarse mode aerosols collected by either small raindrops (dc < 100 μm) or large drops (dc > 100 μm) form aggregations on the surfaces of drops, and accumulation mode aerosols tend to be captured by the aggregations or hydrophobic coarse particles which have been collected by the drops, and this may significantly enhance the capability of the raindrop for fine aerosol collection. When the aggregation effect is considered in the calculation, fine aerosol efficiency can be promoted by one to two orders of magnitude. Therefore, fine particle collision efficiency by raindrops is underestimated by employing the classical dynamic theory which neglects the particle aggregation effect. However, the collection efficiency of coarse particles remains almost constant with the increase in the amount of particles collected by large drops, while there is only a slight increase in efficiency by small raindrops upon increasing in particle concentration. This implies that the traditional limiting trajectory method can still be used for the calculation of coarse particle collection efficiencies by either small or large raindrops. Copyright © 2018 American Association for Aerosol Research
Numerical analysis of the dynamics of aerosol inertial collection and aggregation on raindrops
Creators: name: Zhu, Hui
name: Hua, Fengjiao
name: Kang, Yanming
name: Chen, Yonghang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Astronomical and Space Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: A three dimensional stochastic model is developed for predicting atmospheric aerosol collection and aggregation on the surface of a falling raindrop at its terminal velocity. Potential flow and viscous flow are assumed as the flow fields in the vicinity of the large and the small raindrops, respectively. The results show that hydrophobic coarse mode aerosols collected by either small raindrops (dc< 100μm) or large drops (dc > 100μm) form aggregations on the surfaces of drops, and accumulation mode aerosols tend to be captured by the aggregations or hydrophobic coarse particles which have been collected by the drops, and this may significantly enhance the capability of the raindrop for fine aerosol collection. When the aggregation effect is considered in the calculation, fine aerosol efficiency can be promoted by one to two orders of magnitude. Therefore, fine particle collision efficiency by raindrops is underestimated by employing the classical dynamic theory which neglects the particle aggregation effect. However, the collection efficiency of coarse particles remains almost constant with the increase of the amount of particles collected by large drops, while there is only a slight increase in efficiency by small raindrops when increasing particle concentration. This implies that the traditional limiting trajectory method can still be used for the calculation of coarse particle collection efficiencies by either small or large raindrops.
title: PFC: Enquête Roanne
Creators: name: Modèles, Dynamiques
name: Laks, Bernard
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2011
Subjects: subject: Français
subject: fra
subject: Formel: parcours professionnel. Informel: mariages dans la famille.
subject: phonologie du français
subject: Dialecte de Rhône Alpes
subject: phonetics
subject: phonology
subject: text_and_corpus_linguistics

description: Annotation du fichier de transcription PRAAT de la conversation libre
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Relationship Between Water Migration and Quality Changes of Yellowfin Tuna (Thunnus albacares) During Storage at 0°C and 4°C by LF-NMR
Creators: name: Wang, Xinyun
name: Geng, Lijing
name: Xie, Jing
name: Qian, Yun-Fang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: This study investigated postmortem changes of yellowfin tuna (Thunnus albacares) and water migration upon storage at 0°C and 4°C as determined by low-field nuclear magnetic resonance (LF-NMR 1H). It clearly showed that with increasing storage time, sensory scores and physical evaluations (hardness, chewiness), proton density of the water, and moisture content decreased, while total volatile basic nitrogen (TVB-N), K value, aerobic plate counts (APCs), and psychrotrophic bacterial counts increased. The results of LF-NMR showed that T21 (trapped water) had extremely significant correlations with sensory evaluation, texture profile analysis, TVB-N, K value, APC, and psychrotrophic bacteria (p < 0.01) and established multiple linear regression. It was concluded that the LF-NMR was an important technique to evaluate storage time and temperature of yellowfin tuna’s quality in terms of water migration during low-temperature storage.
Atmospheric particle composition-hygroscopic growth measurements using an in-series hybrid tandem differential mobility analyzer and aerosol mass spectrometer
Creators: name: Schurman, Misha I.
name: Kim, Joo Y.
name: Cheung, Heidi H. Y.
name: Chak K. Chan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The ability of atmospheric particles to absorb water has extensive climate, atmospheric chemistry, and health implications, and considerable effort has gone into determining relationships between particle composition and hygroscopicity. Parallel techniques, in which co-located composition and hygroscopicity measurements are combined to infer composition-hygroscopicity relationships, may not detect the influence of external mixtures. Previous in-line measurements have been limited to single-particle composition or a limited analyte range, and are often non-quantitative and/or offline. Here, we present for the first time in-series, online, quantitative hygroscopicity-composition measurements using a Brechtel Manufacturing, Inc. Hybrid Tandem Differential Mobility Analyzer and an Aerodyne High-Resolution Time-of-Flight Aerosol Mass Spectrometer. This technique is first verified using laboratory-generated external particle mixtures, then extended to ambient measurements at a seaside sampling side at the Hong Kong University of Science and Technology. The technique successfully separated laboratory-generated particles of differing hygroscopicities and showed promise for atmospheric particles, though high mass attenuation endemic to the HTDMA dual size selection limits application to environments with at least ∼14–41 μg/m3 of particulate mass, depending on composition. Copyright © 2017 American Association for Aerosol Research
Transition metal-free direct nucleophilic α-substitution of Morita–Baylis–Hillman alcohols with amines and thiols
Creators: name: Oueslati, Yosra
name: Baioui, Narjes
name: Farhat Rezgui
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Computational Biology

description: An efficient transition metal-free allylic nucleophilic α-substitution of Morita–Baylis–Hillman alcohols with both aliphatic and aromatic amines in refluxing toluene, using activated molecular sieves as additives, is described herein. The reaction proceeded with exclusive α-regioselectivity in moderate to excellent yields with the formation of water as the sole by-product. Under the same conditions, upon treatment of some thiols with the title substrates, allylic sulfides were obtained in excellent yields and high regioselectivity.
Palladium-Catalyzed Deacetonative Coupling of Aryl Propargylic Alcohols with Aryl Chlorides in Water
Creators: name: Chang, Feng
name: Yanping Liu
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: A highly efficient and green process for palladium-catalyzed deacetonative coupling of aryl propargylic alcohols with aryl chlorides has been developed. The reaction occurs smoothly in neat water with 2 mol% PdCl2 as catalyst, and various synthetically useful functional groups, including ether, aldehyde, ketone and heterocyclics, are well tolerated. Moreover, the reaction could proceed through a consecutive Sonogashira/deacetonative process using 2-methyl-3-butyn-2-ol and aryl chlorides as coupling partners, affording the symmetric alkynes in good yields.
Design, Synthesis and Biological Evaluation of Novel Substituted Imidazo[2,1-a] Isoindole Derivatives as Antibacterial Agents
Creators: name: Sirassu Narsimha
name: Kumaraswamy Battula
name: Nagavelli Vasudeva Reddy
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 60506 Virology

description: An efficient protocol has been developed for the synthesis of fused imidazo[2,1-a]isoindol-5-ones (2a-d) from 2-iodo benzoic acids and CDI using one pot Pd-catalyzed C-C bond coupling. The reaction of imidazo[2,1-a]isoindol-5-one (2a-d) with substituted α-bromo ketones in toluene afforded corresponding imidazo[2,1-a]isoindolium derivatives (3a-i) in good yields. The structures of the title compounds were well established on the basis of IR, 1H NMR, 13C NMR, mass spectral data and elemental analysis (C, H and N). In vitro antibacterial results revealed that, the compounds 3b and 3i were found to possessing an excellent broad spectrum of inhibiting potency against all the tested bacterial strains with MIC values ranging from 3.125-25 μgmL−1.
THE IMPORTANCE OF FACIAL ASSESSMENT AND THE USE OF DERMAL FILLERS IN AESTHETIC MEDICINE
Creators: name: Amanda Silva dos Santos, Lima
name: Rodrigo, Cé
Publisher: name: Zenodo
Year: 2024
Subjects: Faciometry, Dermal Fillers, Minimally Invasive Procedures, Preventive Measures

description: Facial beauty is a multifaceted concept, influenced by physical characteristics such as

proportion and symmetry, which are fundamental in aesthetic perception. This study aims to investigate the importance of facial assessment, including the measurement of facial structures and the analysis of facial lines, in the practice of aesthetic medicine. The methodology is based on a comprehensive literature review on techniques of faciometry and facial line analysis, which allow for the identification of

deviations and asymmetries often imperceptible to the naked eye. This section explores facial aging, its

cellular and molecular mechanisms, and the variations in aesthetic perception among different age groups, genders, and ethnicities. The findings indicate that the use of dermal fillers, classified as permanent and non-permanent, is a growing practice in aesthetic medicine, with evident benefits in facial harmonization. However, these procedures are not without risks, particularly in areas such as the nasal region, where severe ocular complications can occur. It is concluded that a detailed evaluation of facial proportions and symmetry combined with a deep understanding of the patient's individual characteristics, is essential for success in aesthetic procedures, promoting a more harmonious and safer aesthetic outcome.
Additional file 1: of The costs and benefits of water fluoridation in NZ
Creators: name: Moore, David
name: Poynton, Matthew
name: Broadbent, Jonathan
name: Thomson, W.
Publisher: name: figshare
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Six additional tables of data. (DOCX 23 kb)
Microwave-assisted synthesis and crystal structure of some novel 1,2,4-oxadiazol-5-ylmethyl-1,2,3-triazoles
Creators: name: Yaşar Dürüst
name: Karakuş, Hamza
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: 60506 Virology

description: Microwave-assisted 1,3-dipolar cycloaddition of 5-azidomethyl 3-aryl-substituted 1,2,4-oxadiazoles to electron-deficient alkyne; phenyl propiolic acid affords a series of 1,2,3-triazole derivatives carrying 3-p-substitutedphenyl-1,2,4-oxadiazolyl methyl unit. The structures of all the cycloadducts were elucidated by IR, NMR (1H, 13C, 2D), MASS (low and high resolution) spectra, X-ray diffraction data, and physical characteristics (melting points and Rf values).
Nucleophilic Addition of Arylmethylzinc Reagents (ArCH2ZnCl) to Formaldehyde: An Easy Access to 2-(Hetro)arylethyl Alcohols
Creators: name: V. P. Bhatt
name: S. D. Samant
name: Suhas Pednekar
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Computational Biology

description: The selective addition of arylmethylmagnesium halides with formaldehyde giving arylethyl alcohols is extremely challenging. To circumvent the difficulties, in the current communication we have reported on the nucleophilic addition of benzyl zinc reagents derived from inexpensive and abundant benzyl chlorides to paraformaldehyde. The reaction investigated herein is hitherto unknown and was found to be selective, operationally simple, atom- and step-economical and high yielding to deliver phenethyl alcohols utilized as key perfumery ingredients in 60-83% yields. After successful establishment of the reaction condition, the reaction was also scaled up successfully to deliver a large scale preparation of the phenethyl alcohol.
Palladium-catalyzed deacetonative coupling of aryl propargylic alcohols with aryl chlorides in water
Creators: name: Chang, Feng
name: Yanping Liu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: A highly efficient and green process for palladium-catalyzed deacetonative coupling of aryl propargylic alcohols with aryl chlorides has been developed. The reaction occurs smoothly in neat water with 2 mol% PdCl2 as catalyst, and various synthetically useful functional groups, including ether, aldehyde, ketone, and heterocyclics, are well tolerated. Moreover, the reaction could proceed through a consecutive Sonogashira/deacetonative process using 2-methyl-3-butyn-2-ol and aryl chlorides as coupling partners, affording the symmetric alkynes in good yields.
MOESM2 of Panicle-SEG: a robust image segmentation method for rice panicles in the field based on deep learning and superpixel optimization
Creators: name: Xiong, Xiong
name: Duan, Lingfeng
name: Liu, Lingbo
name: Tu, Haifu
name: Yang, Peng
name: Wu, Dan
name: Chen, Guoxing
name: Xiong, Lizhong
name: Yang, Wanneng
name: Liu, Qian
Publisher: name: figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology

description: Additional file 2: Appendix S1. The instruction of the Panicle-SEG segmentation software.
Atmospheric Particle Composition-Hygroscopic Growth Measurements Using an In-Series Hybrid Tandem Differential Mobility Analyzer and Aerosol Mass Spectrometer
Creators: name: Schurman, Misha I.
name: Kim, Joo Y.
name: Cheung, Heidi H.Y.
name: Chak K. Chan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology

description: The ability of atmospheric particles to absorb water has extensive climate, atmospheric chemistry, and health implications, and considerable effort has gone into determining relationships between particle composition and hygroscopicity. Parallel techniques, in which co-located composition and hygroscopicity measurements are combined to infer composition-hygroscopicity relationships, may not detect the influence of external mixtures. Previous in-line measurements have been limited to single-particle composition or a limited analyte range, and are often non-quantitative and/or offline. Here, we present for the first time in-series, online, quantitative hygroscopicity-composition measurements using a Brechtel Manufacturing, Inc. Hybrid Tandem Differential Mobility Analyzer and an Aerodyne High-Resolution Time-of-Flight Aerosol Mass Spectrometer. This technique is first verified using laboratory-generated external particle mixtures, then extended to ambient measurements at a seaside sampling side at the Hong Kong University of Science and Technology. The technique successfully separated laboratory-generated particles of differing hygroscopicities and showed promise for atmospheric particles, though high mass attenuation endemic to the HTDMA dual size selection limits application to environments with at least ∼14-41 μg/m3 of particulate mass, depending on composition.
An Improved Process for the Synthesis of Nintedanib Esylate
Creators: name: Veerareddy. Arava
name: Surendrareddy. Gogireddy
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Nintedanib Esylate is synthesized via novel intermediates of (Z)-methyl 3-(acetoxy-phenyl)methylene)-1-acetyl-2-oxoindoline-6-carboxylate and N-(4-aminophenyl)-2-chloro-N-methylacetamide in good yields.
Additional file 1: Table S1. of Does having a usual primary care provider reduce patient self-referrals in rural Chinaâ s rural multi-tiered medical system? A retrospective study in Qianjiang District, China
Creators: name: Feng, Da
name: Zhang, Donglan
name: Li, Boyang
name: Zhang, Yan
name: Serrano, Ray
name: Shi, Danxiang
name: Liu, Yuan
name: Zhang, Liang
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Sample Characteristics after Propensity Score Weighting disease. (DOCX 17Â kb)
title: PFC: Enquête Roanne
Creators: name: Modèles, Dynamiques
name: Laks, Bernard
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2011
Subjects: subject: Français
subject: fra
subject: Formel: petits-enfants
subject: phonologie du français
subject: Dialecte de Rhône Alpes
subject: phonetics
subject: phonology
subject: text_and_corpus_linguistics

description: Annotation du fichier de transcription PRAAT de la conversation libre
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
One-Pot Three-Component Synthesis of Bis(Indolyl)methanes Under Solvent-Free Condition Using Heteropoly-11-Tungsto-1-Vanadophosphoric Acid Supported on Natural Clay as Catalyst
Creators: name: Karuppaiah Selvakumar
name: Thangamariyappan Shanmugaprabha
name: Ramamoorthy Annapoorani
name: Sami, Ponnusamy
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: One-pot three-component condensation reaction of two moles of indole and one mole of aromatic aldehyde for the synthesis of bis(indolyl)methanes in the presence of new catalytic material, heteropoly-11-tungsto-1-vanadophosphoric acid, H4[PVVW11O40] (HPV) supported on activated natural clay under solvent-free reaction condition have been proposed. The catalysts were prepared by incipient wetness impregnation method. The physico-chemical characterizations of the HPV (20%) supported on natural clay (HPVAC-20) have also been discussed. Solvent-free heterogeneous reaction condition, simple workup procedure, short reaction time, high yield of products and reusability of the catalyst are the advantages of the protocol.
Design, synthesis, and biological evaluation of novel substituted imidazo[2,1-a]isoindole derivatives as antibacterial agents
Creators: name: Sirassu Narsimha
name: Kumaraswamy Battula
name: Nagavelli Vasudeva Reddy
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Hematology
subject: 60506 Virology
subject: FOS: Biological sciences

description: An efficient protocol has been developed for the synthesis of fused imidazo[2,1-a]isoindol-5-ones (2a–d) from 2-iodo benzoic acids and N,N-carbonyldiimidazole (CDI) using one-pot Pd-catalyzed C‒C bond coupling. The reaction of imidazo[2,1-a]isoindol-5-one (2a–d) with substituted α-bromo ketones in toluene afforded corresponding imidazo[2,1-a]isoindolium derivatives (3a–i) in good yields. The structures of the title compounds were well established on the basis of infrared (IR), 1H NMR, carbon-13 nuclear magnetic resonance (13C NMR), mass spectral data, and elemental analysis (C, H, and N). In vitro antibacterial results revealed that, the compounds 3b and 3i were found to possess an excellent broad spectrum of inhibiting potency against all the tested bacterial strains with minimum inhibitory concentration values ranging from 3.125 to 25 µg mL−1.
MOESM3 of Panicle-SEG: a robust image segmentation method for rice panicles in the field based on deep learning and superpixel optimization
Creators: name: Xiong, Xiong
name: Duan, Lingfeng
name: Liu, Lingbo
name: Tu, Haifu
name: Yang, Peng
name: Wu, Dan
name: Chen, Guoxing
name: Xiong, Lizhong
name: Yang, Wanneng
name: Liu, Qian
Publisher: name: figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 3: Table S1. The evaluation criterion for the 48 testing rice samples.
title: PFC: Enquête Dijon
Creators: name: Modèles, Dynamiques
name: Laks, Bernard
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2011
Subjects: subject: Français
subject: fra
subject: phonologie du français
subject: Dialecte de Bourgogne
subject: phonetics
subject: phonology
subject: text_and_corpus_linguistics

description: Annotation du fichier de transcription PRAAT de la conversation guidée
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
An improved process for the synthesis of nintedanib esylate
Creators: name: Veerareddy Arava
name: Surendrareddy Gogireddy
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Nintedanib esylate is synthesized via novel intermediates of (Z)-methyl 3-(acetoxy-phenyl)methylene)-1-acetyl-2-oxoindoline-6-carboxylate and N-(4-aminophenyl)-2-chloro-N-methylacetamide in good yields.
title: 01_1461
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Additional file 1: Figure S1. of Site-specific selection reveals selective constraints and functionality of tumor somatic mtDNA mutations
Creators: name: Li, Deyang
name: Du, Xiaohong
name: Guo, Xu
name: Zhan, Lei
name: Li, Xin
name: Yin, Chun
name: Chen, Cheng
name: Li, Mingkun
name: Li, Bingshan
name: Yang, Hushan
name: Xing, Jinliang
Publisher: name: figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Figure S2. and Table S1. (DOCX 833 kb)