cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The role of the inositol phosphatase, SHIP, in the innate immune response to Salmonella Typhimurium
Creators: name: Bishop, Jennifer L.
Publisher: name: University of British Columbia
Year: 2008

description: The SH2 domain-containing inositol 5’-phosphatase, SHIP, negatively regulates hematopoietic cell functions and is critical for maintaining immune homeostasis. However, whether SHIP plays a role in controlling bacterial infections in vivo remained unknown. Salmonella enterica causes human salmonellosis, a disease that ranges in severity from mild gastroenteritis to severe systemic illness, resulting in significant morbidity and mortality worldwide. The focus of this work was to determine the role of SHIP in a murine model of systemic Salmonellosis. Susceptibility of ship⁺/⁺and ship⁻/⁻ mice to S. enterica serovar Typhimurium infection was compared. ship⁻/⁻ mice displayed an increased susceptibility to both oral and intraperitoneal S. Typhimurium infection and had significantly higher bacterial loads in intestinal and systemic sites than ship⁺/⁺mice, indicating a role for SHIP in the gut and systemic pathogenesis of S. Typhimurium in vivo. Blood cytokine levels showed that infected ship⁻/⁻ mice produce lower levels of Th1 polarizing cytokines compared to ship⁺/⁺ animals, and analysis of supernatants taken from M2 bone marrow derived macrophages correlated with this data. M2 macrophages were the predominant population in vivo during both oral and intraperitoneal infections. Because M2 macrophages are poor defenders against bacterial infection, these data suggest that M2 macrophage skewing in ship⁻/⁻ mice contributes to ineffective clearance of Salmonella. The role of SHIP in the gut during enteric infections was also explored. ship⁻/⁻ mice were not susceptible to Citrobacter rodentium infection, yet developed severe inflammation of the ileum upon infection with this bacterium, with Salmonella, or when challenged orally with LPS. Increased collagen deposition was also observed at early time points post-infection, suggesting that ship⁻/⁻ mice may be used to study the development of inflammatory bowel diseases characterized by fibrosis, such as Crohn's. Because SHIP is such a critical negative regulator in both innate and adaptive immune cells, it has the potential to significantly alter the outcome of infections. This work highlights the fact that SHIP is important in vivo during Salmonellosis and opens new avenues to explore targeting SHIP in therapies for both systemic infections as well as inflammatory bowel diseases.
Searby v. McCrust (2); Victoria; 1861.30
Creators: name: (:Null)
Publisher: name: The University of British Columbia
Year: 2019

description: No. of Plaint – 763 Summons; Invoice for £2.7.11 - McCrust is summoned to appear in court to answer the Plaintiff for the total amount of £2.11.11. The amount is due for various goods sold to the Defendant by the Plaintiff.
title: Elective Course Development: Occupational Therapy in the Acute Care Setting
Creators: name: Thompson, Ella
Publisher: name: Georgia State University
Year: 2024

description:
Introduction: Observation, informal discussion with experts<a href="https://studentgsu-my.sharepoint.com/personal/ethompson43_student_gsu_edu/Documents/Documents/0TD%20-%20All%20files/.Capstone/Spring%202024/ET_Capstone%20Final%20Paper_04.24.24.docx#_ftn1" title="">[1], and the literature indicate that occupational therapy (OT) students often enter the acute care setting for Level II Fieldwork (FW II) or new jobs post-graduation with deficits in knowledge, skills, and clinical judgment specifically for the acute care setting (Baird, Raina, Rogers, ODonnell, & Holm, 2015; Gibbs, Dietrich, & Dagnan, 2017; Knecht-Sabres, 2013). Without specific courses in acute care, students in the majority of OT graduate programs do not get extensive exposure to this setting. The development of an elective on OT in acute care for Georgia State Universitys (GSU) OT graduate doctorate program was proposed to address this gap.


Protocol: A literature review was conducted in order to establish a basis for the courses underlying pedagogical models and to determine key elements that made similar programs successful in enhancing student confidence, knowledge, and skill application. A three-week observation at Grady Memorial Hospital was undertaken in order to gain a better understanding of the challenges, knowledge deficits, and skill deficits that FW II educators and students identify as initial impediments early on in the FW II experience. The remaining 11 weeks were dedicated to developing the course and gaining experience in teaching skills labs.


Resulting Program: A 14-unit elective course focused on OT in the acute care setting was designed to increase the confidence, performance skills, and clinical judgment of students in the OT doctorate program at GSU in preparation for FW II in the acute care setting. It follows a flipped classroom model, with asynchronous lectures to be reviewed prior to a hands-on skills lab with real-world simulations and hospital equipment. Underlying pedagogical models include Kolbs Experiential Learning (ELT) Model and more Authentic, Reflective and Collaborative (mARC) instructional design model, with findings that indicate the importance of incorporating self-reflection, debriefing, feedback, and experiential learning.


Conclusion: This course will allow the OT doctorate program at GSU to offer an additional specialized acute care elective course that students can take advantage of in order to increase their knowledge and competency in this practice setting. The offering of such a course also increases the value of GSUs program in the following two areas: (1) the program will be more attractive to students applying to OT school by offering this specialized practice course and (2) local hospitals can expect GSU students who have completed the course to have increased foundational knowledge and skills prior to beginning FW II in acute care.
Additional file 3: of Passive acoustic monitoring reveals group ranging and territory use: a case study of wild chimpanzees (Pan troglodytes)
Creators: name: Ammie Kalan
name: Piel, Alex
name: Mundry, Roger
name: Wittig, Roman
name: Boesch, Christophe
name: Kühl, Hjalmar
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Neuroscience
subject: Ecology
subject: FOS: Biological sciences

description: Chimpanzee drum detection probability at ARUs and chimpanzee ranging activity within a 500 m detection radius of the device in Taï (est ± SE: 0.287 ± 0.12, X2 = 3.50, df = 1, P = 0.061, N = 1410). The dashed line shows the results of the fitted model per 6 hours of ARU recording effort. Data points were binned per 10 hours of chimpanzee activity to obtain a mean detection probability per bin (blue circles). The relative area of the circles corresponds to the log of the number of data points (range: 1 to 1291) per bin. (DOCX 662 kb)
Cryphalus tenuis Schedl 1942
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus tenuis

description: Cryphalus tenuis Schedl, 1942
Cryphalus tenuis Schedl, 1942b: 16.
Distribution. Indonesia (Java), Malaysia.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 199, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Additional file 1: of The impact of reimbursement systems on equity in access and quality of primary care: A systematic literature review
Creators: name: Wenjing Tao
name: Agerholm, Janne
name: Burström, Bo
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biotechnology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Science Policy

description: Search strategy in Web of Science and PubMed, including date and search results. (DOCX 12 kb)
Additional file 1. of Medical liability, defensive medicine and professional insurance in otolaryngology
Creators: name: Motta, Sergio
name: Testa, Domenico
name: Cesari, Ugo
name: Quaremba, Giuseppe
name: Motta, Gaetano
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Questionnaire employed in the survey.
Woo v. Baugh (2); Victoria; 1861.29
Creators: name: (:Null)
Publisher: name: The University of British Columbia
Year: 2019

description: No. of Plaint – 759 Summons; Invoice for £2.5.2 -Baugh is summoned to appear in court to answer the Plaintiff for the total amount of £2.9.2 The amount is due for 13 weeks of washing done by the Plaintiff for the Defendant.
Cryphalus terminaliae Browne 1980
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus terminaliae

description: Cryphalus terminaliae Browne, 1980
Cryphalus terminaliae Browne, 1980b: 384.
Distribution. New Guinea.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 199, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Additional file 1: Figure S1. of Prospectively defined murine mesenchymal stem cells inhibit Klebsiella pneumoniae-induced acute lung injury and improve pneumonia survival
Creators: name: Hackstein, Holger
name: Lippitsch, Anne
name: Krug, Philipp
name: Schevtschenko, Inna
name: Kranz, Sabine
name: Hecker, Matthias
name: Dietert, Kristina
name: Gruber, Achim
name: Bein, Gregor
name: Brendel, Cornelia
name: Baal, Nelli
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Gating strategy for the identification of respiratory leukocyte subsets. Respiratory leukocytes were identified using CD45 surface expression. Respiratory lymphocytes were identified according to low side scatter characteristics and subsequently discriminated into CD19+ B cells, NK1.1+ NK cells, CD3+ γδ TCR+ gamma-delta T cells, CD3+ CD4+ T cells and CD3+ CD8+ T cells. Granulocytes and alveolar macrophages were subsequently identified out of CD45+ leukocytes based on CD11b and GR-1 expression (granulocytes) and CD11c and Siglec F surface expression (alveolar macrophages). DC subsets were subsequently identified out of CD45+ leukocytes based on CD11c expression in SiglecF/NK1.1/Gr1 negative cells to exclude contamination by alveolar macrophages, NK cells and granulocytes. This CD11c positive fraction was further discriminated into CD103+ DC and CD11b DC based on MHC-class II, CD103 and CD11b expression as well as in pDC based on 120 g8 expression and absence of CD11b. Representative figure from n > 10 experiments. (PDF 382 kb)
MOESM1 of Comprehensive evaluation of the liquid fraction during the hydrothermal treatment of rapeseed straw
Creators: name: Wang, Zhi-Wen
name: Zhu, Ming-Qiang
name: Li, Ming-Fei
name: Wang, Jun-Qi
name: Wei, Qin
name: Run-Cang Sun
Publisher: name: Figshare
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Additional file 1: Table S1. Assignments of 13C-1H cross-signals in the HSQC spectra of the liquids fractions obtained during hydrothermal treatment.
Cryphalus tetricus
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus tetricus

description: Cryphalus tetricus (Schedl, 1940)
Ericryphalus tetricus Schedl, 1940: 437; designated by Schedl, 1971a: 275.
Cryphalus papuanus Schedl, 1942a: 170; synonymized by Schedl, 1979a: 95.
Cryphalus grayi Schedl, 1968: 265; synonymized by Schedl, 1979a: 95.
Ptilopodius brevis Browne, 1970: 556; synonymized by Schedl, 1979 q: 256.
Distribution. New Guinea.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 199, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Dimophora
Creators: name: Omatsu, Yuji
name: Kazuhiko Konishi
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Dimophora

description: Key­­­to­­­the­­­Palearctic­­­species­­­of­­­ Dimophora
1. Larger species, fore wing length 3.3–5.0 mm. Antenna with 29 or more flagellomeres. Sub-basal cells of fore and hind wings with setae becoming gradually sparser toward base. Hind wing with 2nd abscissas of CU and AA present............... 2
- Smaller species, fore wing length 2.4–2.6 mm. Antenna with 23 or 24 flagellomeres. Sub-basal cells of fore and hind wings evenly covered with setae. Hind wing with 2nd abscissas of CU and AA absent.................................... 4
2. Tentorial pit located at level dorsad of lower margin of eye. Antenna of female bi-color, brownish yellow and black. Antenna of male entirely dark brown. Fore and mid coxae brownish yellow. 1st metasomal sternite reddish brown. Penis valve with spines weak.................................................................................. D. japonica n. sp.
- Tentorial pit located at level ventrad of lower margin of eye. Antenna in both sexes entirely black. Fore and mid coxae black. 1st metasomal sternite black. Penis valve with spines strong in nigra ............................................ 3
3. OOL/OD=0.8–1.2. Hind leg dark brown. Metasomal tergites entirely black. T2 0.6–0.8 times as long as wide. Ovipositor length about 2.0 mm.............................................................................. D. nigra n. sp.
- OOL/OD=1.6. Hind leg reddish yellow. Metasomal tergites dark brown; around apical 1/3 of T1, T2 and T3 brownish red. T2 0.4 times as long as wide. Ovipositor length about 4.0 mm................................... D. nitens (Gravenhorst)
4. Head 1.8 times as wide as face. POL/OD=1.1. Antenna with or without whitish band. Clypeus entirely black. Propodeal carina complete and distinct.............................................................. D. evanialis (Gravenhorst)
- Head 2.1–2.5 times as wide as face. POL/OD=1.8.Antenna with whitish yellow band.Apical half of clypeus brown. Propodeum with posterior 1/3–1/2 of lateral longitudinal carina of area dentipara absent............................ D. parva n. sp.
description: Published as part of Omatsu, Yuji & Kazuhiko Konishi, 2023, Revision of the genus Dimophora Förster (Hymenoptera: Ichneumonidae: Cremastinae) from Japan, pp. 537-554 in Zootaxa 5278 (3) on page 552, DOI: 10.11646/zootaxa.5278.3.6, http://zenodo.org/record/7906711
Additional file 2: of The impact of reimbursement systems on equity in access and quality of primary care: A systematic literature review
Creators: name: Wenjing Tao
name: Agerholm, Janne
name: Burström, Bo
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Data extraction form for studies included in the systematic review. (DOCX 12 kb)
A right to leave : refugees, states, and international society
Creators: name: Orchard, Philip
Publisher: name: University of British Columbia
Year: 2008

description: This dissertation investigates regime-based efforts by states to cooperate in providing assistance and protection to refugees since 1648. It argues from a constructivist perspective that state interests and identities are shaped both by other actors in the international system - including norm entrepreneurs, non-governmental organizations, and international organizations - and by the broader normative environment. Refugees are a by-product of this environment. Fundamental institutions - including territoriality, popular sovereignty, and international law - formed a system in which exit was one of the few mechanisms of survival for those who were religiously and politically persecuted. This led states to recognize that people who were so persecuted were different from ordinary migrants and had a right to flee their own state and seek accommodation elsewhere. States recognized this right to leave, but did not recognize a requirement that any given state had a responsibility to accept these refugees. This contradiction creates a dilemma in international relations, one which states have sought to solve through international cooperation. The dissertation explores policy change within the United States and Great Britain at the international and domestic levels in order to understand the tensions within current refugee protection efforts. Three regimes, based in different normative understandings, have framed state cooperation. In the first, during the 19th century, refugees were granted protections under domestic and then bilateral law through extradition treaties. The second, in the interwar period, saw states taught by norm entrepreneurs that multilateral organizations could successfully assist refugees, though states remained unwilling to provide blanket assistance and be bound by international law. These issues led to the failure of states to accommodate Jewish refugees fleeing from Germany in the 1930s. The third, since the Second World War, had a greater consistency among its norms, especially recognition by states of the need for international law. Once again, this process was shaped by other actors, including the United Nations High Commissioner for Refugees (UNHCR). This regime has been challenged by increased refugee numbers and restrictions on the part of states, but its central purpose remains robust due to the actions of actors such as the UNHCR.
Additional file 1: of Genetic predisposition to acute kidney injury â   a systematic review
Creators: name: Vilander, Laura
name: Kaunisto, Mari
name: PettilĂ¤, Ville
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: Search strategy in Ovid Medline. (PDF 32Â kb)
Cryphalus theobromae Nunberg 1956
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus theobromae

description: Cryphalus theobromae Nunberg, 1956
Cryphalus theobromae Nunberg, 1956: 208.
Cryphalus horridus Graham, 1908: 113; synonymized by Nunberg, 1956: 208.
Distribution. Africa (Ghana).
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 199, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Additional file 3: of Genetic predisposition to acute kidney injury â   a systematic review
Creators: name: Vilander, Laura
name: Kaunisto, Mari
name: PettilĂ¤, Ville
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy

description: Studies published only as abstracts. (PDF 205Â kb)
Additional file 1: of Protocol of the Low Birth Weight South Asia Trial (LBWSAT), a cluster-randomised controlled trial testing impact on birth weight and infant nutrition of Participatory Learning and Action through womenâ  s groups, with and without unconditional transfers of fortified food or cash during pregnancy in Nepal
Creators: name: Saville, Naomi
name: Bhim Shrestha
name: Style, Sarah
name: Harris-Fry, Helen
name: B. Beard
name: Sengupta, Aman
name: Jha, Sonali
name: Rai, Anjana
name: Paudel, Vikas
name: Anni-Maria Pulkki-Brannstrom
name: Copas, Andrew
name: Skordis-Worrall, Jolene
name: Bishnu Bhandari
name: Rishi Neupane
name: Morrison, Joanna
name: Gram, Lu
name: Raghbendra Sah
name: Machhindra Basnet
name: Harthan, Jayne
name: Dharma Manandhar
name: Osrin, David
name: Costello, Anthony
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy

description: Nutrient content of 150 g daily intake of WFP wheat-soya with sugar Super Cereal food supplement, in relation to the nutrients listed in the DFID TORs, FAO-WHO vitamin and mineral requirements [50]. Remarks contain notes about nutrients where appropriate. (PDF 324 kb)
Role of Bcl-2 proteins in neutrophil activation and delayed apoptosis in crystal-induced arthritis
Creators: name: Higo, Tobi T.
Publisher: name: University of British Columbia
Year: 2008

description: The inflammatory response caused by the deposition of crystals of monosodium urate monohydrate (MSUM) and calcium pyrophosphate dihydrate (CPPD) in the synovial fluid of joints, results from the interaction of the crystals with neutrophils. Neutrophils (whose function in the body is to remove hazardous microorganisms and inflammatory debris) are activated by the binding of the crystals to the neutrophil cellular membrane, which leads to respiratory burst activity, engulfment of the crystals and release of proteolytic enzymes. Furthermore, we have found that crystals delay the normal “cell death program” or apoptosis, thus allowing for the accumulation of these cells, and extended inflammatory responses. Very little is known about the mechanisms of activation and delay of apoptosis, however, bcl-2 family proteins have been implicated in the control of neutrophil apoptosis. This study helps to define the role of several bcl-2 family proteins (both pro- and anti-apoptotic) by examining the differential expression of these proteins upon stimulation with crystals. Subsequent identification of signaling targets that function to regulate this process in response to crystals could lead to potential therapeutics for crystal-induced inflammatory diseases.
Cryphalus triangularis
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus triangularis

description: Cryphalus triangularis (Schedl, 1975)
Hypocryphalus triangularis Schedl, 1975a: 351; designated by Johnson et al., 2020: 24.
Distribution. New Guinea.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 199, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Additional file 4: Table S2. of Monocot and dicot MLO powdery mildew susceptibility factors are functionally conserved in spite of the evolution of class-specific molecular features
Creators: name: Appiano, Michela
name: Catalano, Domenico
name: MartĂ­Nez, Miguel SantillĂĄn
name: Lotti, Concetta
name: Zheng, Zheng
name: Visser, Richard
name: Ricciardi, Luigi
name: Yuling Bai
name: Pavan, Stefano
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer

description: Primer pairs used in this study. (DOCX 14 kb)
MOESM1 of Transcriptomes of a xylose-utilizing industrial flocculating Saccharomyces cerevisiae strain cultured in media containing different sugar sources
Creators: name: Zeng, Wei-Yi
name: Tang, Yue-Qin
name: Gou, Min
name: Xia, Zi-Yuan
name: Kida, Kenji
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1: Supplementary material.
Additional file 6: of Genetic predisposition to acute kidney injury â   a systematic review
Creators: name: Vilander, Laura
name: Kaunisto, Mari
name: PettilĂ¤, Ville
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy

description: Quality scoring of the 28 full articles. (PDF 129Â kb)
Hydrichthella Stechow 1909
Creators: name: Wang, Lianggen
name: Du, Feiyan
name: Xu, Zhenzu
name: Huang, Jiaqi
name: Guo, Donghui
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Cnidaria
Hydrozoa
Anthoathecata
Ptilocodiidae
Hydrichthella

description: Genus Hydrichthella Stechow, 1909
Hydrichthella Stechow, 1909: 31; Hirohito, 1988: 142, 144; Bouillon et al., 2006: 153; Xu et al., 2014: 265.
Hydrichthelloides Bouillon, 1978: 55; Bouillon, 1985: 59.
Type species: Hydrichthella epigorgia Stechow, 1905.
Diagnosis. Hydroid. Colony usually growing on sea fans, hydrorhiza encrusting, covered by naked coenosarc, or consisting of perisarc-covered reticular stolons pending substrate; gastrozooid tubular, without tentacles; hypostome studded by nematocysts; dactylozooids hollow, without mouth, with two types: one with many capitate tentacles and the other filiform, with capitate tip; gonozooids similar to gastrozooids in shape, bearing eumedusoids.
Medusa. Reduced to short-living eumedusoids, with 4 radial canals and subumbrellar cavity, with manubrium not eccentric; with 8 non-tentacular bulbs; gonads on manubrium; with or without ocelli.
Remarks. The genus Hydrichthella shares with Hydrichthelloides the hydroids colony polymorphic and dactylozooids of two types: one with many capitate tentacles and the other filiform with capitate tips. Type species of both genera show distinct from the structure of hydrorhiza: Hydrichthelloides reticula Bouillon, 1978 consists of perisarc, covered reticular stolons pending substrate; Hydrichthella epigorgia Stechow, 1909 is encrusting, covered by naked coenosarc. The systematic value of this distinguished character is questionable even at the generic level. Hirohito (1988) treated Hydrichthelloides as a synonym of Hydrichthella.
The genus Hydrichthella comprised two species: the hydroid H. epigorgia Stechow, 1909 from the East China Sea, Japan, Indonesia, Papua New Guinea and Seychelles Island (Hirohito, 1988; Tang & Gao, 2008; Xu et al., 2014) and H. reticulata (Bouillon, 1978) from Papua New Guinea (Bouillon, 1978). In the present work, a new medusa species, H. ocellata Xu, Huang & Wang, sp. nov., collected from the South China Sea with red ocelli on the 8 non-tentacular bulbs which suggests it should be a new species of the genus.
description: Published as part of Wang, Lianggen, Du, Feiyan, Xu, Zhenzu, Huang, Jiaqi & Guo, Donghui, 2017, Taxonomical notes on the family Ptilocodiidae (Anthomedusae) from the central and southern of South China Sea, with a new genus and a new species, pp. 236-242 in Zoological Systematics 42 (2) on page 238, DOI: 10.11865/zs.201713, http://zenodo.org/record/4617015
Additional file 3: of Protocol of the Low Birth Weight South Asia Trial (LBWSAT), a cluster-randomised controlled trial testing impact on birth weight and infant nutrition of Participatory Learning and Action through womenâ  s groups, with and without unconditional transfers of fortified food or cash during pregnancy in Nepal
Creators: name: Saville, Naomi
name: Bhim Shrestha
name: Style, Sarah
name: Harris-Fry, Helen
name: B. Beard
name: Sengupta, Aman
name: Jha, Sonali
name: Rai, Anjana
name: Paudel, Vikas
name: Anni-Maria Pulkki-Brannstrom
name: Copas, Andrew
name: Skordis-Worrall, Jolene
name: Bishnu Bhandari
name: Rishi Neupane
name: Morrison, Joanna
name: Gram, Lu
name: Raghbendra Sah
name: Machhindra Basnet
name: Harthan, Jayne
name: Dharma Manandhar
name: Osrin, David
name: Costello, Anthony
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Computational Biology

description: Information sheet and consent form for menstrual monitoring or pregnancy follow-up. (DOCX 24 kb)
Cryphalus trypanoides Beeson 1935
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus trypanoides

description: Cryphalus trypanoides Beeson, 1935
Cryphalus trypanoides Beeson, 1935: 106.
Distribution. Hawaiian Islands, Marquesa Islands.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 199, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Additional file 2: Figure S1. of Monocot and dicot MLO powdery mildew susceptibility factors are functionally conserved in spite of the evolution of class-specific molecular features
Creators: name: Appiano, Michela
name: Catalano, Domenico
name: MartĂ­Nez, Miguel SantillĂĄn
name: Lotti, Concetta
name: Zheng, Zheng
name: Visser, Richard
name: Ricciardi, Luigi
name: Yuling Bai
name: Pavan, Stefano
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Expression levels of PsMLO1 and HvMLO after transformation. Panel A) and panel B) show the expression of PsMLO1 and HvMLO in 19 and 20Â T1 individuals, respectively, which were obtained by the transformation of the tomato mutant line Slmlo1, harboring a loss-of-function mutation of the endogenous SlMLO1 gene. Asterisks indicate T1 individuals selected for self-pollination and the development of T2 families. (PDF 173 kb)
Additional file 7: of Genetic predisposition to acute kidney injury â   a systematic review
Creators: name: Vilander, Laura
name: Kaunisto, Mari
name: PettilĂ¤, Ville
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: PRISMA Checklist for systematic review. (PDF 117Â kb)
Additional file 2: of Protocol of the Low Birth Weight South Asia Trial (LBWSAT), a cluster-randomised controlled trial testing impact on birth weight and infant nutrition of Participatory Learning and Action through womenâ  s groups, with and without unconditional transfers of fortified food or cash during pregnancy in Nepal
Creators: name: Saville, Naomi
name: Bhim Shrestha
name: Style, Sarah
name: Harris-Fry, Helen
name: B. Beard
name: Sengupta, Aman
name: Jha, Sonali
name: Rai, Anjana
name: Paudel, Vikas
name: Anni-Maria Pulkki-Brannstrom
name: Copas, Andrew
name: Skordis-Worrall, Jolene
name: Bishnu Bhandari
name: Rishi Neupane
name: Morrison, Joanna
name: Gram, Lu
name: Raghbendra Sah
name: Machhindra Basnet
name: Harthan, Jayne
name: Dharma Manandhar
name: Osrin, David
name: Costello, Anthony
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Information sheet showing different paragraphs inserted for different study arms. (DOCX 24 kb)
Additional file 3: Figure S2. of Monocot and dicot MLO powdery mildew susceptibility factors are functionally conserved in spite of the evolution of class-specific molecular features
Creators: name: Appiano, Michela
name: Catalano, Domenico
name: Martínez, Miguel Santillán
name: Lotti, Concetta
name: Zheng, Zheng
name: Visser, Richard
name: Ricciardi, Luigi
name: Yuling Bai
name: Pavan, Stefano
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Plant Biology
subject: Computational Biology

description: Effects of transgenic overexpression of pea PsMLO1 and barley HvMLO in the tomato mutant line Slmlo1. Average disease index (DI) values and phenotypes are referred to transgenic plants of two additional T2 families segregating for PsMLO1 [35S::PsMLO1-4 and 35S::PsMLO1-6, panel a) and b)] and two additional T2 families segregating for HvMLO [35S::HvMLO-10 and 35S::HvMLO-15), panel c) and d)]. Data relative to the Slmlo1 mutant line, used as genetic background for transformation, and non-transgenic plants of three T2 families for each overexpression construct (35S::PsMLO1_(−) and 35S::HvMLO_(−)) are also shown. (PDF 304 kb)
Cryphalus trypanus Sampson 1914
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus trypanus

description: Cryphalus trypanus Sampson, 1914 *
Cryphalus trypanus Sampson, 1914: 383.
Distribution. China (Yunnan), Africa (Seychelles Islands).
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 200, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Rhodes v. Richards (3); Victoria; 1861.28
Creators: name: (:Null)
Publisher: name: The University of British Columbia
Year: 2019

description: No of Plaint – 758 Summons; Invoice for £15.12.6; Judgment Confessed - Richards is summoned to appear in court to answer the Plaintiff for the total amount of £16.14. The amount is due on an unpaid promissory note between the Defendant and the Plaintiff.
Hydrichthella ocellata Xu, Huang & Wang 2017, sp. nov.
Creators: name: Wang, Lianggen
name: Du, Feiyan
name: Xu, Zhenzu
name: Huang, Jiaqi
name: Guo, Donghui
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Cnidaria
Hydrozoa
Anthoathecata
Ptilocodiidae
Hydrichthella
Hydrichthella ocellata

description: Hydrichthella ocellata Xu, Huang & Wang, sp. nov. (Figs 1–4)
Material examined. Holotype SFI 001, southern of South China Sea, st. B4 (10°16'N, 114°13'E), depth 2000 m, sampling depth 20–0 m, 22 May 2014, colls. Shen Chen & Jie Li (SFRI).
Diagnosis. Free eumedusoid, umbrella nearly spherical; with short and wide gastric peduncle, with 4 large mass-like gonads, interradial on manubrium; bell margin with 8 non-tentacular bulbs, 4 perradial larger than 4 interradial bulbs, each with a distinct red ocellus at the extreme tip.
Description. Medusa reduced to short-living eumedusoid; umbrella up to 1 mm high, nearly as wide as high in preserved specimen; mesoglea about 1/3–1/4 diameter of exumbrella; exumbrella covered with nematocysts, without exumbrellar furrows and didermic centripetal tracks; manubrium hanging from short and wide peduncle, mouth more or less quadratic in shape with simple mouth lips; 4 gonads interradial, extending to adradial on manubrium, smooth without folded; with 4 radial canals and circular canal; umbrella margin with 8 non-tentacular bulbs, 4 perradial larger than 4 interradial bulbs, each with a distinct red ocellus at the extreme tip; velum middle broad.
Hydroid. Unknown.
Distribution. Southern South China Sea.
Etymology. The specific name refers to the Latin ocellata, meaning ocellus. The eumedusoid name refers to the marginal bulbs each with a red ocellus at the extreme tip.
Remarks. Although only one specimen was found, its good preservation of morphological characters suggests that a new eumedusoid is present. The eumedusoid of Hydrichthella ocellata Xu, Huang & Wang, sp. nov. is very similar to the eumedusoid of H. epigorgia Stechow, 1909 (redescribed by Hirohito (1988)), by the bearing eumedusoids with four radial canals, 8 marginal bulbs, 4 large, mass-like gonads, interradial positions on manubrium, with velum. But the eumedusoid of H. ocellata Xu, Huang & Wang, sp. nov. is clearly different from H. epigorgia by free swimming eumedusoid with exumbrellar scattered nematocysts, with a short and wide gastric peduncle, 8 marginal bulbs, 4 perradial bulbs larger than 4 interradial bulbs, each with a red ocellus at the extreme tip (Figs 1–4).
description: Published as part of Wang, Lianggen, Du, Feiyan, Xu, Zhenzu, Huang, Jiaqi & Guo, Donghui, 2017, Taxonomical notes on the family Ptilocodiidae (Anthomedusae) from the central and southern of South China Sea, with a new genus and a new species, pp. 236-242 in Zoological Systematics 42 (2) on pages 238-239, DOI: 10.11865/zs.201713, http://zenodo.org/record/4617015
title: Enabling next-generation particle cascade simulations
title: Implementing the propagation software PROPOSAL as an interaction model for CORSIKA 8
titleType: AlternativeTitle
Creators: name: Alameddine, Jean-Marco
Publisher: name: TU Dortmund
Year: 2024
Subjects: subject: Physik
subject: Astroteilchenphysik
subject: Luftschauersimulation
subject: Monte-Carlo-Simulation
subject: 530
subject: Astrophysik
subject: Luftschauer
subject: Monte-Carlo-Simulation

description: The observation of cosmic messenger particles provides unique insights into astrophysical processes. As high-energy nuclei or photons reach the Earth's atmosphere, a particle cascade called extensive air shower is initiated. By detecting secondary shower particles, the energy, direction, and identity of the initial messenger particle can be reconstructed. This task heavily relies on an accurate simulation of particle cascades. A major challenge in this context is the muon puzzle – a significant, as yet unresolved muon deficit in air shower simulations compared to experimental observations. To overcome limitations of existing shower simulation codes, the next-generation simulation framework CORSIKA 8 is currently under development. This work describes the implementation of the Monte Carlo simulation code PROPOSAL as the first electromagnetic and muonic interaction model in CORSIKA 8. PROPOSAL describes muon interactions with maximal precision, minimizing possible systematic uncertainties in the description of the muonic shower component in CORSIKA 8. The code structure of PROPOSAL is modularized, and a description of electromagnetic processes is implemented. An interface between CORSIKA 8 and PROPOSAL is written, which is validated by comparisons with previous CORSIKA versions. Notably, these validations reveal that CORSIKA 8 shows a 5% increase of muons in hadronic showers. As this number is insufficient to solve the muon puzzle, inaccuracies in muon propagation are ruled out as a possible cause. Furthermore, this work allows for the first physics-complete shower simulations with CORSIKA 8, which is a crucial step toward its first release. For the scientific community, CORSIKA 8 is going to be a powerful tool for the simulation and investigation of particle cascades, especially to further understand and solve the muon puzzle.
MOESM1 of A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: towards future combination therapies
Creators: name: Bisht, Savita
name: Schlesinger, Martin
name: Rupp, Alexander
name: Schubert, Rolf
name: Nolting, Jens
name: Jรถrg Wenzel
name: Holdenrieder, Stefan
name: Brossart, Peter
name: Bendas, Gerd
name: Feldmann, Georg
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Additional file 1. Additional information.
Cryphalus tutuilaensis
Creators: name: Yang, Liyuan
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cryphalus
Cryphalus tutuilaensis

description: Cryphalus tutuilaensis (Schedl, 1951)
Hypocryphalus tutuilaensis Schedl, 1951: 147; designated by Johnson et al., 2020: 24.
Distribution. Samoan Islands.
description: Published as part of Yang, Liyuan, 2020, Checklist of the genus Cryphalus Erichson, 1836 (Coleoptera: Curculionidae: Scolytinae) with special attention to Chinese species, pp. 176-205 in Zoological Systematics 45 (3) on page 200, DOI: 10.11865/zs.202023, http://zenodo.org/record/10109545
Tregouboviopsis Guo, Xu & Huang 2017, gen.
Creators: name: Wang, Lianggen
name: Du, Feiyan
name: Xu, Zhenzu
name: Huang, Jiaqi
name: Guo, Donghui
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Cnidaria
Hydrozoa
Anthoathecata
Ptilocodiidae
Tregouboviopsis

description: Genus Tregouboviopsis Guo, Xu & Huang, gen. nov.
Type species: Tregoubovia perradialis Xu, Huang & Du, 2012.
Diagnosis. Ptilocodiidae medusae spherical; without tentacles; bell margin with nematocyst ring from which originate didermic centripetal tracks running meridionally on exumbrella; manubrium large, mouth quadratic with simple and long, unbranched oral tentacles, arising above mouth rim, unarmed terminal nematocyst clusters, and with ring nematocysts along the whole length of the oral tentacles; gonads very large, covering perradial on manubrium well, with mescenteries; without ocelli.
Hydroid. Unknown.
Remarks. The species Tregoubovia perradialis Xu, Huang & Du, 2012 is originally described under the genus Tregoubovia by the distinctness of simple unbranched oral tentacles, without marginal tentacles and exumbrella with didermic centripetal tracks. By reexamining the type specimens, its positions of oral tentacles and gonads are different from Tregoubovia atentaculata Picard, 1958, the type species of the genus. T. atentaculata has 4 oral arms extending directly from the perradial corners of mouth margin, with one terminal nematocyst clusters; gonads on interradial manubrium (Fig. 5), while T. perradialis has 4 oral tentacles arising above mouth rim, unarmed terminal nematocyst clusters, and with ring nematocysts along the whole oral tentacles; gonads on perradial manubrium (Figs 6–7). Therefore, the species T. perradialis is removed from the genus Tregoubovia and a new genus Tregouboviopsis Guo, Xu & Huang, gen. nov. is erected to accommodate it.
Etymology. The genus name is derived from the Latin tregouboviopsis, meaning Tregoubovi-opsis, referring to external characters of both genera are nearly resemble.
description: Published as part of Wang, Lianggen, Du, Feiyan, Xu, Zhenzu, Huang, Jiaqi & Guo, Donghui, 2017, Taxonomical notes on the family Ptilocodiidae (Anthomedusae) from the central and southern of South China Sea, with a new genus and a new species, pp. 236-242 in Zoological Systematics 42 (2) on pages 239-240, DOI: 10.11865/zs.201713, http://zenodo.org/record/4617015
Additional file 1 of Sort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relations
Creators: name: Peterman, Neil
name: Levine, Erel
Publisher: name: Figshare
Year: 2016
Subjects: subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Supplementary Figures with figure legends. Figure S1: Bias and efficiency of the simple mean estimator. Figure S2: Bias and efficiency of maximum likelihood estimators. Figure S3: Bias and efficiency of the simple CV estimator. Figure S4: MLE mean and CV using a yeast-promoter dataset. Figure S5: MLE mean for sort-seq data with combined gates. Figure S6: MLE CV for sort-seq data with combined gates. Figure S7: Enrichment measurements from different input distributions. Figure S8: Enrichment estimates using re-grouped gates from two sort-seq datasets. (PDF 3755 kb)
Additional file 5: of Genetic predisposition to acute kidney injury â   a systematic review
Creators: name: Vilander, Laura
name: Kaunisto, Mari
name: PettilĂ¤, Ville
Publisher: name: Figshare
Year: 2015
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy

description: Articles studying AKI-related outcome. (PDF 213Â kb)
Drug–drug interaction potential among patients with nonmetastatic castration-resistant prostate cancer (nmCRPC) treated with novel androgen receptor inhibitors
Creators: name: Appukkuttan, Sreevalsa
name: Ko, Gilbert
name: Fu, Chunmay
name: Bannister, Breyanne
name: Kong, Sheldon X.
name: Jhaveri, Jay
name: Freedland, Stephen J.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Nonmetastatic castration-resistant prostate cancer (nmCRPC) patients are often older and use concurrent medications that increase the potential for drug–drug interactions (pDDIs). This study assessed pDDI prevalence in real-world nmCRPC patients treated with apalutamide, darolutamide, or enzalutamide. Castrated prostate cancer patients without metastases prior to androgen receptor inhibitor initiation were identified retrospectively via Optum Clinformatics Data Mart claims data (8/2019–3/2021). The top 100 concomitant medications were assessed for pDDIs. Among 1,515 patients (mean age: 77 ± 8 years; mean Charlson Comorbidity Index: 3 ± 3), 340 initiated apalutamide, 112 darolutamide, and 1,063 enzalutamide. Common concomitant medication classes were cardiovascular (80%) and central nervous system (52%). Two-thirds of the patients received ≥5 concomitant medications; 30 (30/100 medications) pDDIs were identified for apalutamide and enzalutamide each and 2 (2/100 medications) for darolutamide. Most pDDIs had risk ratings of C or D, but four for apalutamide were rated X. Approximately 58% of the patients on apalutamide, 5% on darolutamide, and 54% on enzalutamide had ≥1 identified pDDI. Results showed a higher frequency of pDDIs in patients receiving apalutamide and enzalutamide vs darolutamide. The impact of these could not be determined retrospectively. DDI risk should be carefully evaluated when discussing optimal therapy for patients with nmCRPC.