cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Association of Cord Serum Cytokines with Neurodevelopmental Outcomes
Creators: name: O'Sullivan, Mary
name: Iams, Jay
name: Dudley, Donald
name: Peaceman, Alan
name: Sorokin, Yoram
name: Malone, Fergal
name: Hankins, Gary
name: Varner, Michael
name: Leveno, Kenneth
name: Carpenter, Marshall
name: Wapner, Ronald
name: Reddy, Uma
name: Caritis, Steve
name: Jablonski, Kathleen
name: Rouse, Dwight
name: Thorp, John
name: Mercer, Brian
name: Marshall, Nicole
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: To test whether elevated umbilical cord serum inflammatory cytokine levels predicted subsequent cerebral palsy (CP) or neurodevelopmental delay (NDD).
Materiały do poznania wybranych rodzin żądłówek (Hymenoptera: Aculeata) Biebrzańskiego Parku Narodowego
Creators: name: Waldemar Żyła
name: Tomasz Jaworski
name: Radosław Plewa
name: Cezary Bystrowski
name: Grzegorz Tarwacki
name: Krzysztof Sućko
name: Jacek Hilszczański
Publisher: name: Zenodo
Year: 2023
Subjects: Hymenoptera, Aculeata, Crabronidae, Sphecidae, Pompilidae, Tiphiidae, Mutillidae, Sapygidae, Scoliidae, Vespidae, Biebrza National Park, Masurian Lake District, Podlasie, Poland

description: Contribution to the knowledge of selected families of stinging wasps (Hymenoptera: Aculeata) of Biebrza National Park. The paper presents faunistic data on 182 species from selected families of stinging wasps (Crabronidae, Sphecidae, Pompilidae, Mutillidae, Sapygidae, Scoliidae, Tiphiidae and Vespidae) from the Biebrza National Park (North East Poland). The research was carried out in 2020-2022. Specimens were collected in 6 types of habitats, both unburned and affected by the fire that occurred in April 2020, with the use of Moericke traps (i.e. yellow pan traps) and Lindgren traps (purple 12-funnel traps). Prionyx kirbii (Vander Linden, 1827) is new to the Polish fauna and Ectemnius nigritarsus (Herrich-Schaeffer, 1841) is confirmed after 110 years in Poland. Furthermore, 51 species are new to the fauna of the Masurian Lake District and 5 species are new to the Podlasie Region.
La filière de la psychiatrie à Tonnerre : une étude de cas
Creators: name: , DANTOU
Publisher: name: Zenodo
Year: 2023
Subjects: sociologie mobilité précarité psychiatrie déplacement contrainte migration rural

description: Ce texte constitue le point de départ de la troisième partie de ma thèse consacrée aux déplacements de personnes précarisées dans la ville de Tonnerre. Il s'agit de la partie sociologique de la thèse. J'ai tenté un travail de mise en perspective par des statistiques localisées et quelques schémas, qui pourraient être largement améliorés. Je pense que ce texte pourrait tout à fait s'accompagner d'une série de photographies qui ne feraient pas le lien avec Élisa. Je souhaiterais soumettre ce texte pour la publication d'un article scientifique dans une revue de sociologie ou d'ethnographie.
Automorphisms of braid groups on orientable surfaces
Creators: name: An, Byung Hee
Publisher: name: arXiv
Year: 2015
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: Primary 20F36, Secondary 20F28, 32G15

description: In this paper we compute the automorphism groups $\operatorname{Aut}(\mathbf{P}_n(Σ))$ and $\operatorname{Aut}(\mathbf{B}_n(Σ))$ of braid groups $\mathbf{P}_n(Σ)$ and $\mathbf{B}_n(Σ)$ on every orientable surface $Σ$, which are isomorphic to group extensions of the extended mapping class group $\mathcal{M}^*_n(Σ)$ by the transvection subgroup except for a few cases. We also prove that $\mathbf{P}_n(Σ)$ is always a characteristic subgroup of $\mathbf{B}_n(Σ)$ unless $Σ$ is a twice-punctured sphere and $n=2$.
description: 27 pages
(100705) Helen Burnet Mundy
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Interaction of Acoustic and Optical Phonons in Soft Bonded Cu-Se Framework of Large Unit Cell Minerals with Anionic Disorders
Creators: name: Rana, Kewal Singh
name: Gupta, Raveena
name: Sarkar, Debattam
name: Singh, Niraj Kumar
name: Acharya, Somnath
name: Vitta, Satish
name: Bera, Chandan
name: Biswas, Kanishka
name: Soni, Ajay
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: Large unit cell copper-chalcogenide based minerals with high crystalline anharmonicity have a potential for thermoelectric applications owing to their inherent poor lattice thermal conductivity. Here, the softening of copper-selenium bonding and hence crystal framework plays an important role in superionic conduction and thermal conductivity. We have studied Cu26Nb2Sn6Se32, Cu26Nb2Sn6Se31.5 and Cu26Nb2Sn6Se30Te2 minerals with a strategically tailored anionic disorders. These compounds have p-type degenerate behavior with carrier concentration ranging between 1020 cm-3 at 300 K, high power factor and low lattice thermal conductivity at 640 K. The existence of two low frequency Raman active optical modes associated with soft Cu and Se atoms, three localized Einstein modes in specific heat, suggest high scattering between acoustic and optical branches with very short phonon lifetime less than 1 ps. The excess vibrational density of states at low energies with compressed and flat optical branches strongly hinders the heat transport in these crystalline mineral. Comparatively, Cu26Nb2Sn6Se30Te2 is a promising thermoelectric material because of high crystalline anharmonicity and softening of Cu-Se framework due to heavier tellurium atom.
description: 20 Pages, 14 figures in main text and supporting information
Inverse design of disordered stealthy hyperuniform spin chains
Creators: name: Chertkov, Eli
name: DiStasio, Robert A.
name: Zhang, Ge
name: Car, Roberto
name: Torquato, Salvatore
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Positioned between crystalline solids and liquids, disordered many-particle systems which are stealthy and hyperuniform represent new states of matter that are endowed with novel physical and thermodynamic properties. Such stealthy and hyperuniform states are unique in that they are transparent to radiation for a range of wavenumbers around the origin. In this work, we employ recently developed inverse statistical-mechanical methods, which seek to obtain the optimal set of interactions that will spontaneously produce a targeted structure or configuration as a unique ground state, to investigate the spin-spin interaction potentials required to stabilize disordered stealthy hyperuniform one-dimensional (1D) Ising-like spin chains. By performing an exhaustive search over the spin configurations that can be enumerated on periodic 1D integer lattices containing $N=2,3,\ldots,36$ sites, we were able to identify and structurally characterize \textit{all} stealthy hyperuniform spin chains in this range of system sizes. Within this pool of stealthy hyperuniform spin configurations, we then utilized such inverse optimization techniques to demonstrate that stealthy hyperuniform spin chains can be realized as either unique or degenerate disordered ground states of radial long-ranged (relative to the spin chain length) spin-spin interactions. Such exotic ground states are distinctly different from spin glasses in both their inherent structural properties and the nature of the spin-spin interactions required to stabilize them. As such, the implications and significance of the existence of such disordered stealthy hyperuniform ground state spin systems warrants further study, including whether their bulk physical properties and excited states, like their many-particle system counterparts, are singularly remarkable, and can be experimentally realized.
description: 11 pages, 9 figures
On the role of gestures in human-robot interaction
Creators: name: CARFI', ALESSANDRO
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: This thesis investigates the gestural interaction problem and in particular the usage of gestures for human-robot interaction. The lack of a clear definition of the problem statement and a common terminology resulted in a fragmented field of research where building upon prior work is rare. The scope of the research presented in this thesis, therefore, consists in laying the foundation to help the community to build a more homogeneous research field. The main contributions of this thesis are twofold: (i) a taxonomy to define gestures; and (ii) an ingegneristic definition of the gestural interaction problem. The contributions resulted is a schema to represent the existing literature in a more organic way, helping future researchers to identify existing technologies and applications, also thanks to an extensive literature review. Furthermore, the defined problem has been studied in two of its specialization: (i) direct control and (ii) teaching of a robotic manipulator, which leads to the development of technological solutions for gesture sensing, detection and classification, which can possibly be applied to other contexts.
Resource Efficient Large-Scale Machine Learning
Creators: name: CARRATINO, LUIGI
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: Non-parametric models provide a principled way to learn non-linear functions. In particular, kernel methods are accurate prediction tools that rely on solid theoretical foundations. Although they enjoy optimal statistical properties, they have limited applicability in real-world large-scale scenarios because of their stringent computational requirements in terms of time and memory. Indeed their computational costs scale at least quadratically with the number of points of the dataset and many of the modern machine learning challenges requires training on datasets of millions if not billions of points. In this thesis, we focus on scaling kernel methods, developing novel algorithmic solutions that incorporate budgeted computations. To derive these algorithms we mix ideas from statistics, optimization, and randomized linear algebra. We study the statistical and computational trade-offs for various non-parametric models, the key component to derive numerical solutions with resources tailored to the statistical accuracy allowed by the data. In particular, we study the estimator defined by stochastic gradients and random features, showing how all the free parameters provably govern both the statistical properties and the computational complexity of the algorithm. We then see how to blend the Nystr�m approximation and preconditioned conjugate gradient to derive a provably statistically optimal solver that can easily scale on datasets of millions of points on a single machine. We also derive a provably accurate leverage score sampling algorithm that can further improve the latter solver. Finally, we see how the Nystr�m approximation with leverage scores can be used to scale Gaussian processes in a bandit optimization setting deriving a provably accurate algorithm. The theoretical analysis and the new algorithms presented in this work represent a step towards building a new generation of efficient non-parametric algorithms with minimal time and memory footprints.
Phytochemical composition and biological activity of extracts from Lebanese medicinal plants
Creators: name: KHALIL, MOHAMAD
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: The Mediterranean area especially the eastern part including Lebanon, is rich in term of plant biodiversity, including high valuable medicinal plants that are largely used by people as herbal medicine, these plants represent an important source of plant-derived bioactive compounds, besides, there is a need to characterize these compounds, evaluate their bioactivity and clarify scientifically the use of these plant as traditional and alternative medicine, lack of these information may limit their use, by contrast, studying the compositions and bioactivity of these plants may improve their use, discovery of new natural bioactive compounds and finally formulate new plant-based nutraceutical and therapeutically agents. In this context, the aim of my PhD thesis, and as a part of our ongoing program in the medicinal plants filed, was the characterization of a pool of phytochemical compounds with a special focus on polyphenols isolated from different medicinal plants from the Lebanese flora, using analytical tools (as described later in the chapters) including high-performance liquid chromatography (HPLC) coupled with different detectors such as UV-visible and electrospray ioniziation (ESI) Mass spectrometry (MS), following by the study of their biological activities using different in vitro cellular well-established model for several chronic diseases. The plants that I choose for my study have a significant value in the traditional medicine in Lebanon, where they are employed as a food but also in folk medicine to treat/prevent many illnesses. I employed different cellular models of oxidative stress and related chronic diseases (NAFLD, inflammation and cancer).
Thermal boundary resistance at Si/Ge interfaces determined by approach-to-equilibrium molecular dynamics simulations
Creators: name: Hahn, Konstanze R.
name: Puligheddu, Marcello
name: Colombo, Luciano
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The thermal boundary resistance of Si/Ge interfaces as been determined using approach-to-equilibrium molecular dynamics simulations. Assuming a reciprocal linear dependence of the thermal boundary resistance, a length-independent bulk thermal boundary resistance could be extracted from the calculation resulting in a value of 3.76x10$^{-9}$ m$^2$ K/W for a sharp Si/Ge interface and thermal transport from Si to Ge. Introducing an interface with finite thickness of 0.5 nm consisting of a SiGe alloy, the bulk thermal resistance slightly decreases compared to the sharp Si/Ge interface. Further growth of the boundary leads to an increase in the bulk thermal boundary resistance. When the heat flow is inverted (Ge to Si), the thermal boundary resistance is found to be higher. From the differences in the thermal boundary resistance for different heat flow direction, the rectification factor of the Si/Ge has been determined and is found to significantly decrease when the sharp interface is moderated by introduction of a SiGe alloy in the boundary layer.
description: 7 pages, 6 figures
Calculation of Dynamical Response Functions Using a Bound-state Method
Creators: name: Walet, Niels R.
name: Singh, Jagjit
name: Kirscher, Johannes
name: Birse, Michael C.
name: Griesshammer, Harald W.
name: McGovern, Judith A.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We investigate a method to extract response functions (dynamical polarisabilities) directly from a bound-state approach applied to calculations of perturbation-induced reactions. The use of a square-integrable basis leads to a response in the form of a sum of $δ$ functions. We integrate this over energy and fit a smooth function to the resulting stepwise-continuous one. Its derivative gives the final approximation to the physical response function. We show that the method reproduces analytical results where known, and analyse the details for a variety of models. We apply it to some simple models, using the Stochastic Variational Method as the numerical method. Although we find that this approach, and other numerical techniques, have some difficulties with the threshold behaviour in coupled-channel problems with multiple thresholds, its stochastic nature allows us to extract robust results even for such cases.
(100707) Alice Constance Hignett
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Mean-field ansatz for topological phases with string tension
Creators: name: Dusuel, S.
name: Vidal, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a simple mean-field ansatz to study phase transitions from a topological phase to a trivial phase. We probe the efficiency of this approach by considering the string-net model in the presence of a string tension for any anyon theory. Such a perturbation is known to be responsible for a deconfinement-confinement phase transition which is well described by the present variational setup. We argue that mean-field results become exact in the limit of large total quantum dimension.
description: 12 pages, 4 figures, typos in Table I corrected
Negativity and strong monogamy of multi-party quantum entanglement beyond qubits
Creators: name: Choi, Jin Hyuk
name: Kim, Jeong San
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose the square of convex-roof extended negativity(SCREN) as a powerful candidate to characterize strong monogamy of multi-party quantum entanglement. We first provide a strong monogamy inequality of multi-party entanglement using SCREN, and show that the tangle-based multi-qubit strong monogamy inequality can be rephrased by SCREN. We further show that SCREN strong monogamy inequality is still true for the counterexamples that violate tangle-based strong monogamy inequality in higher-dimensional quantum systems rather than qubits. We also analytically show that SCREN strong monogamy inequality is true for a large class of multi-qudit states, a superposition of multi-qudit generalized W-class states and vacuums. Thus SCREN is a good alternative to characterize the strong monogamy of entanglement even in multi-qudit systems.
description: 10 pages, no figure
(100704) Cecil Trelawney Mundy
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(100706) Annie Willis
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A Framework for the Semantics-aware Modelling of Objects
Creators: name: SCALAS, ANDREAS
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: The evolution of 3D visual content calls for innovative methods for modelling shapes based on their intended usage, function and role in a complex scenario. Even if different attempts have been done in this direction, shape modelling still mainly focuses on geometry. However, 3D models have a structure, given by the arrangement of salient parts, and shape and structure are deeply related to semantics and functionality. Changing geometry without semantic clues may invalidate such functionalities or the meaning of objects or their parts. We approach the problem by considering semantics as the formalised knowledge related to a category of objects; the geometry can vary provided that the semantics is preserved. We represent the semantics and the variable geometry of a class of shapes through the parametric template: an annotated 3D model whose geometry can be deformed provided that some semantic constraints remain satisfied. In this work, we design and develop a framework for the semantics-aware modelling of shapes, offering the user a single application environment where the whole workflow of defining the parametric template and applying semantics-aware deformations can take place. In particular, the system provides tools for the selection and annotation of geometry based on a formalised contextual knowledge; shape analysis methods to derive new knowledge implicitly encoded in the geometry, and possibly enrich the given semantics; a set of constraints that the user can apply to salient parts and a deformation operation that takes into account the semantic constraints and provides an optimal solution. The framework is modular so that new tools can be continuously added. While producing some innovative results in specific areas, the goal of this work is the development of a comprehensive framework combining state of the art techniques and new algorithms, thus enabling the user to conceptualise her/his knowledge and model geometric shapes. The original contributions regard the formalisation of the concept of annotation, with attached properties, and of the relations between significant parts of objects; a new technique for guaranteeing the persistence of annotations after significant changes in shape's resolution; the exploitation of shape descriptors for the extraction of quantitative information and the assessment of shape variability within a class; and the extension of the popular cage-based deformation techniques to include constraints on the allowed displacement of vertices. In this thesis, we report the design and development of the framework as well as results in two application scenarios, namely product design and archaeological reconstruction.
The planar limit of integrated 4-point functions
Creators: name: Fiol, Bartomeu
name: Kong, Ziwen
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We compute the planar limit, as all-order power series in the 't Hooft coupling, of various integrated 4-point functions of chiral primary operators of ${\cal N}=4$ SU(N) super Yang-Mills, and of moment map operators of ${\cal N}=2$ SU(N) SQCD. We do so by computing the planar free energy on $S^4$ of the respective massive deformations of these theories, and then taking advantage of the exact relation between these free energies and the integrated 4-point functions.
description: 23 pages
(100700) Frederick Mowbray Berkeley Calcott
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Catalogo pianoforti Clement Anni 70
Creators: name: Doliana, Claudio
Publisher: name: Zenodo
Year: 2023

description: La fabbrica A. Bozzetta & C. di Tésero, in provincia di Trento, ha prodotto i pianoforti a marchio Clement per vari decenni, dall'inizio degli anni Cinquanta alla fine degli anni Ottanta del XX secolo. In questo dépliant degli anni Settanta vengono spiegate le caratteristiche dei vari modelli, sia verticali che a mezzacoda.
pyMOR - Generic Algorithms and Interfaces for Model Order Reduction
Creators: name: Milk, René
name: Rave, Stephan
name: Schindler, Felix
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mathematical Software (cs.MS)
subject: Numerical Analysis (math.NA)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: 35-04, 35J20, 35L03, 65-04, 65N30, 65Y05, 68N01

description: Reduced basis methods are projection-based model order reduction techniques for reducing the computational complexity of solving parametrized partial differential equation problems. In this work we discuss the design of pyMOR, a freely available software library of model order reduction algorithms, in particular reduced basis methods, implemented with the Python programming language. As its main design feature, all reduction algorithms in pyMOR are implemented generically via operations on well-defined vector array, operator and discretization interface classes. This allows for an easy integration with existing open-source high-performance partial differential equation solvers without adding any model reduction specific code to these solvers. Besides an in-depth discussion of pyMOR's design philosophy and architecture, we present several benchmark results and numerical examples showing the feasibility of our approach.
Ventricular expression of natriuretic peptides in Npr1 −/− mice  with cardiac hypertrophy and fibrosis
Creators: name: Smithies, O.
name: Kim, H.-S.
name: Maeda, N.
name: Cameron, V. A.
name: Ellmers, L. J.
name: Knowles, J. W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are cardiac hormones that regulate blood pressure and volume, and exert their biological actions via the natriuretic peptide receptor-A gene (Npr1). Mice lacking Npr1 (Npr–/–) have marked cardiac hypertrophy and fibrosis disproportionate to their increased blood pressure. This study examined the relationships between ANP and BNP gene expression, immunoreactivity and fibrosis in cardiac tissue, circulating ANP levels, and ANP and BNP mRNA during embryogenesis in Npr1–/– mice. Disruption of the Npr1 signaling pathway resulted in augmented ANP and BNP gene and ANP protein expression in the cardiac ventricles, most pronounced for ANP mRNA in females [414 ± 57 in Npr1–/– ng/mg and 124 ± 25 ng/mg in wild-type (WT) by Taqman assay, P < 0.001]. This increased expression was highly correlated to the degree of cardiac hypertrophy and was localized to the left ventricle (LV) inner free wall and to areas of ventricular fibrosis. In contrast, plasma ANP was significantly greater than WT in male but not female Npr1–/– mice. Increased ANP and BNP gene expression was observed in Npr1–/– embryos from 16 days of gestation. Our study suggests that cardiac ventricular expression of ANP and BNP is more closely associated with local hypertrophy and fibrosis than either systemic blood pressure or circulating ANP levels.
Characterization of Uterine NK Cells in Women with Infertility or Recurrent Pregnancy Loss and Associated Endometriosis
Creators: name: Parkin, Kirstin L.
name: Lessey, Bruce A.
name: Fazleabas, Asgerally T.
name: Giuliani, Emma
name: Young, Steven L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Uterine natural killer cells (uNK) have been thought to play a key role in endometriosis and infertility. We investigated the expression of CD56, CD16 and NKp46 in endometrial tissues from 61 women with unexplained recurrent pregnancy loss (uRPL) or infertility (UI), and correlated this with the presence or absence of endometriosis. The results from the patients with sub-fertility were compared to those from 10 fertile patients.
Polymorphisms in Inflammatory Genes are Associated with Term Small for Gestational Age and Preeclampsia
Creators: name: Engel, Stephanie M.
name: Harmon, Quaker E.
name: Avery, Christy L.
name: Wu, Michael C.
name: Luo, Jingchun
name: Olshan, Andrew F.
name: Stuebe, Alison M.
name: Moran, Thomas M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Inflammatory biomarkers are associated with preeclampsia (PE) and poor fetal growth; however, genetic epidemiologic studies have been limited by reduced gene coverage and the exclusion of African American mothers.
Гармонизация глобализации на основе предельных динамических и сетевых равновесий
Creators: name: Кожевников Николай Николаевич
name: Данилова Вера Софроновна
Publisher: name: Век глобализации
Year: 2019
Subjects: ОТКРЫТОЕ ОБРАЗОВАНИЕ
ПРИРОДА
КУЛЬТУРА
САМООРГАНИЗАЦИЯ
ДИАЛОГ
ВЗАИМОДЕЙСТВИЕ
ПОРЯДОК
ХАОС
ДИНАМИЧЕСКИЕ РАВНОВЕСИЯ
СЕТЕВАЯ ЯЧЕЙКА

description: Глобализация и глобальные процессы рассмотрены с точки зрения трех фундаментальных пределов: идентификации, коммуникации, ритмов мировой гармонии, которые являются ядром системы координат мира на основе динамических и сетевых равновесий детерминистического хаоса. Глобализироваться может только нечто предварительно идентифицированное, сформировавшееся, равновесное. Коммуникация и устойчивые ритмы мировой гармонии также должны стремиться к динамическим равновесиям, что обеспечивается взаимосвязью между всеми уровнями глобальных процессов в культурно-цивилизационных сетях в контексте постнеклассического универсализма.
MESENCHYMAL STEM CELLS: MECHANISMS INVOLVED IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
Creators: name: SALA, EMANUELA
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: Background. Mesenchymal stem cells (MSC) based on their immune-modulatory and anti-inflammatory properties have been candidate as therapeutic treatment for several immune disease including inflammatory bowel disease (IBD). Although most of beneficial effects are explained by MSC engrafting at the site of tissue injury with modulation of inflammatory reactions, the mechanisms by which MSC exert their activities needed to be elucidated. Aim of this study was to investigate the mechanisms underlying the therapeutic efficacy of MSC in Dextran Sodium Sulphate (DSS) induced colitis. Methods. Colitis was induced in C57BL6 mice by 3% DSS treatment for 10 days. MSC were isolated from bone marrow of wild type (WT) and GFP-transgenic C57BL6 mice, cultured for 4 weeks and then sorted for Sca-1+, CD31-, cocktail lineage- surface markers. At day 5 of colitic induction the mice were treated intraperitoneally with a single injection of 3x106 GFP-MSC or with 5 daily injections of recombinant murine TNF?-stimulating gene protein 6 (TSG-6) (4 ?g). Body weight and disease activity index (DAI) were monitored daily and the damage of murine colonic mucosa was evaluated by endoscopic and histological scores. To follow the migratory activity of the MSC, GFP-MSC were injected intraperitoneally in healthy or colitic mice at day 5 and their presence was assessed by flow cytometry after 24 and 48 hours in the colon and mesenteric lymph nodes. Levels of TSG-6, IL-6 and IFN-? were measured in serum and in mucosal extracts by ELISA, while MMP activities were quantified by WB. Results. We found that one injected into the peritoneum MSC remain into the peritoneal cavity, where they aggregate along with macrophages and lymphocytes, generating organized structures. Only a small fraction (< 1%) of cells reached the inflamed colon. In vitro and in vivo assays have demonstrated that MSC secrete a multipotent anti-inflammatory protein TSG-6 able to reduce the damage to the colon. In fact, recombinant murine TSG-6 treatment improved survival rate and DSS-induced colitis by reducing markedly both systemic and mucosal levels of IL-6, IFN-?, neutrophil infiltration, and MMP activities. Conclusions. Overall, these data indicate that the MSC gut-homing is not relevant for exerting their immunomodulatory effects, but MSC dampen the mucosal inflammatory response at distance by releasing a potent anti-inflammatory protein.
(100701) William Lunell Guinness
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
LOCOREGIONAL DELIVERY OF UNMETHYLATED CPG-OLIGODEOXYNUCLEOTIDES TO CANCER THERAPY: PRECLINICAL STUDIES
Creators: name: SOMMARIVA, MICHELE
Publisher: name: Universit� degli Studi di Milano
Year: 2010

description: Tumor cell growth, even in advanced stages of ovarian cancer, is nearly always restricted to the peritoneal cavity, therefore repeated intraperitoneal injections of CpG-ODN recruiting and activating innate effector cells throughout the abdominal cavity to the tumor site might control tumor cell growth and ascites formation. After a single CpG-ODN treatment, in IGROV-1 ovarian tumor ascites-bearing athymic mice, the number of tumor cells declined rapidly and markedly, and ascites volumes declined shortly after treatment (5 h), increasing thereafter at a slower rate than in controls. When administered every 7 days for 4 weeks, CpG-ODN had only a marginal effect on survival time, whereas administration 5 days/week for 3 or 4 weeks led to a significantly increased survival-time as compared to controls and completely controlled ascites growth without apparent toxicity, although a disorganization of lymphoid organs was observed. Depletion of NK or monocytes/macrophages only slightly influenced the CpG-ODN-induced reduction of ascites tumor cells, indicating that the antitumor activity might not be related to a specific cell/cytokine but rather to the repertoire of cells and cytokines accumulated in the peritoneal cavity. Thus, our data suggest a relevant role for repeated activation of cells and cytokines of innate immunity in the therapy of ovarian cancer patients with malignant ascites. However, daily i.p. administration of CpG-ODN induced a significant increase of survival-time but no cure of a single mouse, therefore we screened the effectiveness of CpG-ODN in combination with different agents, including bevacizumab, Poly(I):Poly(C) and cisplatin. Our data indicate that the combination of repeated i.p. CpG-ODN treatments plus bevacizumab and Poly(I):Poly(C) do not significantly increase median survival time, while the association of CpG-ODN and cisplatin revealed a significant increase in mice lifespan. Based on these results, we performed several experments in order to gain inside the molecular mechanisms by which CpG-ODN improves the therapeutic efficacy of cisplatin, a DNA-damaging drug. We demonstrate that an immunostimulatory Toll-like receptor-9 (TLR9) agonist CpG-oligodeoxynucleotide (CpG-ODN) oppositely modulates expression of DNA repair genes in tumor and immune cells. Analyses in silico and in a human ovarian tumor model by microarray revealed downregulation of these genes in tumors and upregulation in immune cells, with no detectable modulation in normal non-immune tissue. CpG-ODN induced activation of cells present in the tumor microenvironment was critical in inducing DNA-repair gene modulation in tumors. In conclusion, the combination of cisplatin with CpG-ODN was effective and well tolerated, and might represent a preclinical basis for the design of clinical studies, even considering the ability of CpG-ODN to down-modulate DNA repair genes in tumor cell.
(100702) Susannah Newton
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The Relationship Between Standardized Measures of Language and Measures of Spontaneous Speech in Children With Autism
Creators: name: Meyer, Echo
name: Tager-Flusberg, Helen
name: Condouris, Karen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: This study investigated the relationship between scores on standardized tests (Clinical Evaluation of Language Fundamentals [CELF], Peabody Picture Vocabulary Test–Third Edition [PPVT-III], and Expressive Vocabulary Test) and measures of spontaneous speech (mean length of utterance [MLU], Index of Productive Syntax, and number of different word roots [NDWR]) derived from natural language samples obtained from 44 children with autism between the ages of 4 and 14 years old. The children with autism were impaired across both groups of measures. The two groups of measures were significantly correlated, and specific relationships were found between lexical–semantic measures (NDWR, vocabulary tests, and the CELF lexical–semantic subtests) and grammatical measures (MLU, and CELF grammar subtests), suggesting that both standardized and spontaneous speech measures tap the same underlying linguistic abilities in children with autism. These findings have important implications for clinicians and researchers who depend on these types of language measures for diagnostic purposes, assessment, and investigations of language impairments in autism.
Precision Comparison of the Power Spectrum in the EFTofLSS with Simulations
Creators: name: Foreman, Simon
name: Perrier, Hideki
name: Senatore, Leonardo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the prediction of the dark matter power spectrum at two-loop order in the Effective Field Theory of Large Scale Structures (EFTofLSS) using high precision numerical simulations. In our universe, short distance non-linear perturbations, not under perturbative control, affect long distance fluctuations through an effective stress tensor that needs to be parametrized in terms of counterterms that are functions of the long distance fluctuating fields. We find that at two-loop order it is necessary to include three counterterms: a linear term in the over density, $δ$, a quadratic term, $δ^2$, and a higher derivative term, $\partial^2δ$. After the inclusion of these three terms, the EFTofLSS at two-loop order matches simulation data up to $k\simeq 0.34 \,h\, {\rm Mpc}^{-1}$ at redshift $z=0$, up to $k\simeq 0.55\,h\, {\rm Mpc}^{-1}$ at $z=1$, and up to $k\simeq 1.1\,h\, {\rm Mpc}^{-1}$ at $z=2$. At these wavenumbers, the cosmic variance of the simulation is at least as small as $10^{-3}$, providing a high precision comparison between theory and data. The actual reach of the theory is affected by theoretical uncertainties associated to not having included higher order terms in perturbation theory, for which we provide an estimate, and by potentially overfitting the data, which we also try to address. Since in the EFTofLSS the coupling constants associated with the counterterms are unknown functions of time, we show how a simple parametrization gives a sensible description of their time-dependence. Overall, the $k$-reach of the EFTofLSS is much larger than previous analytical techniques, showing that the amount of cosmological information amenable to high-precision analytical control might be much larger than previously believed.
description: v2: JCAP published version, added comments and explanations
CORTE COSTITUZIONALE E CONVENZIONE EUROPEA DEI DIRITTI DELL'UOMO: RILIEVI CRITICI E ASPETTI PROBLEMATICI DI UN NUOVO INQUADRAMENTO FONDATO SULL'ART. 117, COMMA 1, COST.
Creators: name: FUSARO, PAOLO
Publisher: name: Universit� degli Studi di Milano
Year: 2010

description: The present research analyzes the jurisprudence of the italian Constitutional Court regarding the Convention for the Protection of Human Rights and Fundamental Freedoms. Since the decisions n� 348 and 349 of 2007 the Constitutional Court assures a stronger incidence of the international treaties on the italian law system, this study aims to underline the critical points and the possible consequences of this situation, suggesting alternatives and correctives.
UMUMIY O'RTA TA'LIM MAKTABIDA TASVIRIY SAN'ATNI O'QITISH METODIKASI
Creators: name: OCHILOVA, LATOFAT
Publisher: name: Zenodo
Year: 2023

description: Metodika - bu to'plangan tajriba, yangi yondashuvlar, o'quvchilar va o'qituvchining o'zini ma'naviy va hissiy rivojlantirish vositalarini izlash. Va keyin o'qitish usullari, ehtimol, dastur mazmunining ma'lum bir qismini o'zlashtirish uchun o'qituvchi va talabalarning yagona faoliyati tizimidir. U o'qituvchi va o'quvchining o'ziga xos harakatlari, texnikasi, turli xil aloqa shakllari bilan amalga oshiriladi.
Communicative Gesture Use in Infants With and Without Autism: A Retrospective Home Video Study
Creators: name: Watson, Linda R.
name: Wilson, Kaitlyn P.
name: Dykstra, Jessica R.
name: Crais, Elizabeth R.
name: Baranek, Grace T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Compare gesture use in infants with autism to infants with other developmental disabilities (DD) or typical development (TD).
An accurate fluid approximation for massive neutrinos in cosmology
Creators: name: Nascimento, Caio
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: A measurement of the neutrino mass scale will be achieved with cosmological probes in the upcoming decade. On one hand, the inclusion of massive neutrinos in the linear perturbation theory of cosmological structure formation is well understood and can be done accurately with state of the art Boltzmann solvers. On the other hand, the numerical implementation of the Boltzmann equation is computationally expensive and is a bottleneck in those codes. This has motivated the development of more efficient fluid approximations, despite their limited accuracy over all scales of interest, $k \sim (10^{-3}-10)$Mpc$^{-1}$. In this work we account for the dispersive nature of the neutrino fluid, i.e., the scale dependence in the sound speed, leading to an improved fluid approximation. We show that overall $\lesssim 5\%$ errors can be achieved for the neutrino density and velocity transfer functions at redshift $z \lesssim 5$, which corresponds to an order of magnitude improvement over previous approximation schemes that can be discrepant by as much as a factor of two.
description: 10+8 pages, 7 figures. Matching prd accepted version
Radikale Kreatürlichkeit. Zur Sphäre der erinnernden Körperlichkeit in Paul Celans Fadensonnen-Gedichten
Creators: name: Runge, Maximilian
Publisher: name: Zenodo
Year: 2015
Subjects: Paul Celan
Poetry
philosophy of existence
mysticism
holocaust
Shoa

description: In his 1968 poetry collection „Fadensonnen“, Paul Celan offers a hermetic blend of existentialism and mysticism, which is unusual in two respects. Firstly, the European philosophy of existence, especially with its proponents Jean-Paul Sartre, Albert Camus and Martin Heidegger, had gone to great lengths to criticize and delegitimize the Abrahametic religions, for the concept of god seemed to be an obstacle to humanity in pursuit of its own humanization. Secondly, in the aftermath of the holocaust, the idea of man wanting to merge with a god that had not prevented this cruelty from happening had lost much of its plausibility. Despite these two objections, Celan's poems address the struggle of togetherness in a world that negates the mere possibility of otherness, trying to salvage the unique identity and dignity of the other. With this in mind, the modus operandi of his poems is that of a butcher: Whatever has previously been alive – before the Shoah – now has to be stripped bare of its layers of individual and collective history, has to become less than body and flesh. In this way, the poems' inherent pain and misery transform the reader into a nobody, for only a nobody has got the prerequisites to encounter other people unbiasedly in their unique wholeness. Within this space of encounter, only the reminiscence of body and sexuality exists, commemorating the other, so that radical corporeality seems to be the prerequisite for togetherness. In this ahistorical sphere there is no room for a god that permitted the holocaust, redefining mysticism as the connection between men instead of one between man and god. Celan's poems act as a catalyst, for they exclude god from the spheres of man, making poetry a memorial site to the dead and the ones living in pain. This way, the poems are trying to save Eros (in the sense of creaturely love) from being mutilated by the crimes of European history while at the same time aiming at rehabilitating mankind in a post-holocaust world.