cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Concept Drift and Anomaly Detection in Graph Streams
Creators: name: Zambon, Daniele
name: Alippi, Cesare
name: Livi, Lorenzo
Publisher: name: arXiv
Year: 2017
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Graph representations offer powerful and intuitive ways to describe data in a multitude of application domains. Here, we consider stochastic processes generating graphs and propose a methodology for detecting changes in stationarity of such processes. The methodology is general and considers a process generating attributed graphs with a variable number of vertices/edges, without the need to assume one-to-one correspondence between vertices at different time steps. The methodology acts by embedding every graph of the stream into a vector domain, where a conventional multivariate change detection procedure can be easily applied. We ground the soundness of our proposal by proving several theoretical results. In addition, we provide a specific implementation of the methodology and evaluate its effectiveness on several detection problems involving attributed graphs representing biological molecules and drawings. Experimental results are contrasted with respect to suitable baseline methods, demonstrating the effectiveness of our approach.
Neuromuscular adaptations after osseointegration of a bone-anchored prosthesis in a unilateral transfemoral amputee – a case study
Creators: name: Krauskopf, Thomas
name: Lauck, Torben
name: Meyer, Britta
name: Klein, Lukas
name: Mueller, Marc
name: Kubosch, Johanna
name: Herget, Georg
name: von Tscharner, Vinzenz
name: Ernst, Jennifer
name: Stieglitz, Thomas
name: Pasluosta, Cristian
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: Developmental Biology
subject: Cancer

description: Many individuals with a lower limb amputation experience problems with the fitting of the socket of their prosthesis, leading to dissatisfaction or device rejection. Osseointegration (OI)- the implantation of a shaft directly interfacing with the remaining bone- is an alternative for these patients. In this observational study, we investigated how bone anchoring influences neuromuscular parameters during balance control in a patient with a unilateral transfemoral amputation. Center of pressure (CoP) and electromyography (EMG) signals from muscles controlling the hip and the ankle of the intact leg were recorded during quiet standing six months before and one and a half years after this patient underwent an OI surgery. Results were compared to a control group of nine able-bodied individuals. Muscle co-activation and EMG intensity decreased after bone anchoring, approaching the levels of able-bodied individuals. Muscle co-activation controlling the ankle decreased in the high-frequency range, and the EMG intensity spectrum decreased in the lower-frequency range for all muscles when vision was allowed. With eyes closed, the ankle extensor muscle showed an increased EMG intensity in the high-frequency range post-surgery. CoP length increased in the mediolateral direction of the amputated leg. These findings point to shifts in the patient’s neuromuscular profile towards the one of able-bodied individuals.
Necessary and sufficient conditions for consistent root reconstruction in Markov models on trees
Creators: name: Fan, Wai-Tong Louis
name: Roch, Sebastien
Publisher: name: arXiv
Year: 2017
Subjects: subject: Probability (math.PR)
subject: Information Theory (cs.IT)
subject: Statistics Theory (math.ST)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences
subject: 60J25, 60J80, 62B10, 62M05

description: We establish necessary and sufficient conditions for consistent root reconstruction in continuous-time Markov models with countable state space on bounded-height trees. Here a root state estimator is said to be consistent if the probability that it returns to the true root state converges to 1 as the number of leaves tends to infinity. We also derive quantitative bounds on the error of reconstruction. Our results answer a question of Gascuel and Steel and have implications for ancestral sequence reconstruction in a classical evolutionary model of nucleotide insertion and deletion.
description: 30 pages, 3 figures, title of reference [FR] is updated
From Wintrobe to the XXI century. A Story of Inspiration and Effort
Creators: name: E. Urrechaga
name: J.J.M.L. Hoffmann
name: J.F. Escanero
Publisher: name: figshare
Year: 2018
Subjects: subject: 111704 Community Child Health
subject: FOS: Health sciences

description: In 2014 we are celebrating the 80th anniversary of the Maxwell Myer Wintrobe´s pioneer works, one of the most important contributions in Clinical Laboratory and Medicine. Red cell indices continue to provide an essential support to the diagnosis and classification of anemia. The erythrocyte indices mean cell volume, mean cell hemoglobin concentration, mean cell hemoglobin are called the Wintrobe indices. Hematology automation has progressed steadily since Wallace Coulter first applied electrical impedance technology to counting red cells and white cells. Technological advances being incorporated into hematology analyzers since then are now allowing the access to more cellular information than was ever available before through a “simple routine CBC”. Current research is beginning to demonstrate that this information also has great potential to identify cellular changes that typically occur in several important medical conditions—bringing us all one step closer to using hematology analyzers as more than simple cell counters, but instead as powerful tools for the management of any medical condition that impacts the biology of blood cells. There are increasing amounts of data provided, which require specialist knowledge to interpret as well as understand the limitations in the measurement of the parameter. Both laboratory scientists and clinicians need to keep up to date with new parameters and methods in hematology, implying a stronger collaboration between them to improve clinical decision making.
Investigating anorectal function using postoperative MRI-based fibrosis score in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy: a two-center study
Creators: name: Yuan, Yuan
name: Yu, Yue
name: Sun, Yi Qun
name: Li, Shuai
name: Di Lu, Hai
name: Lu, Xiao
name: Lu, Jian Ping
name: Shao, Cheng Wei
name: Zhang, Wei
name: Tong, Tong
name: Gao, Xian Hua
name: Shen, Fu
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Cell Biology
Pharmacology
Biological Sciences not elsewhere classified
Cancer
Mental Health

description: This study aimed to develop a postoperative MRI-based fibrosis scoring system and to assess its correlation with anorectal function in locally advanced rectal cancer (LARC) cases administered neoadjuvant chemoradiotherapy (nCRT). Pathologically confirmed LARC cases administered nCRT and radical resection were assessed retrospectively. Based on postoperative magnetic resonance imaging (MRI) findings, anastomotic fibrosis score (AFS) and perirectal fibrosis score (PFS) were determined to evaluate the extent of fibrosis. The Wexner continence score for anorectal function was obtained 2 years postoperatively and assessed for correlation with MRI fibrosis scores. The cases were divided into 2 groups by the median Wexner score. Univariable and multivariable analyses were adopted for building a nomogram model, whose diagnostic performance was estimated by receiver operating characteristic (ROC) and decision curve analyses (DCA). Finally, 144 patients with LARC were included in cohort 1 (training set). 52 patients were enrolled in cohort 2 (external validation set). Spearman correlation analysis indicated that AFS and PFS were positively correlated with the Wexner score. Univariable and multivariable analyses revealed age, tumor height, AFS, and PFS were independent predictors of anorectal function. The nomogram model achieved a good diagnostic performance, with AUCs of 0.800 and 0.827 in the training and validation sets, respectively; its predicting value was also confirmed by DCA. The present study showed AFS and PFS derived from postoperative MRI are positively correlated with Wexner score. In addition, the new scoring system was effective in predicting anorectal function in LARC cases administered nCRT.
Evaluation of oral small molecule drugs for the treatment of COVID-19 patients: a systematic review and network meta-analysis
Creators: name: Chen, Zhaoyan
name: Tian, Fangyuan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Biotechnology
Cancer
Science Policy

description: At present, there are some randomized controlled trials (RCTs) of oral small molecule drugs. The purpose of this study was to evaluate the efficacy and safety of oral small molecule drug treatment for COVID-19. RCTs were identified through systematic searches of PubMed, Embase, and Cochrane Central Register of Controlled Trials through 1 April 2023. A total of nine RCTs were included, including 30,970 COVID-19 patients comparing five treatments (azvudine, molnupiravir, paxlovid, VV116, and placebo). The Cochrane risk of bias tool for randomized trials (RoB) was used to assess the bias risk of the included studies. The direct and indirect evidence were combined using a Bayesian network meta-analysis (PROSPERO Code No: CRD42023397837). Direct analysis showed that paxlovid was associated with a reduced risk of mortality (odds ratio [OR] 0.12, 95% confidence interval [CI] 0.06–0.25) and hospitalization (OR = 0.04, 95% CI: 0.00–0.67) compared with placebo. Network meta-analysis showed that paxlovid had the highest probability of being the best management strategy in patients with COVID-19, reducing mortality (OR = 0.11, 95% CI: 0.01–1.99; surface under the cumulative ranking curve [SUCRA]: 0.77) and hospitalization (OR = 0.06, 95% CI: 0.00–1.03; SUCRA: 0.95). For prespecified safety outcomes, SUCRA values ranked VV116 (OR = 0.09, 95% CI: 0.00–2.07: SUCRA 0.86) as the most beneficial intervention for the prevention of serious adverse events. When compared to other antiviral medications, paxlovid can reduce the mortality and hospitalization of COVID-19 patients.
Schwinger Pair Production by Electric Field Coupled to Inflaton
Creators: name: Geng, Jia-Jia
name: Li, Bao-Fei
name: Soda, Jiro
name: Wang, Anzhong
name: Wu, Qiang
name: Zhu, Tao
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We analytically investigate the Schwinger pair production in the de Sitter background by using {\em the uniform asymptotic approximation method}, and show that the equation of motion in general has two turning points, and the nature of these points could be single, double, real or complex, depending on the choice of the free parameters involved in the theory. Different natures of these points lead to different electric currents. In particular, when $β\equiv m^2/H^2-9/4$ is positive, both turning points are complex, and the electric current due to the Schwinger process is highly suppressed, where $m$ and $H$ denote, respectively, the mass of the particle and the Hubble parameter. For the turning points to be real, it is necessary to have $β< 0$, and the more negative of $β$, the easier to produce particles. In addition, when $β< 0$, we also study the particle production when the electric field $E$ is very weak. We find that the electric current in this case is proportional to $E^{1/2 - \sqrt{|β|}}$, which is strongly enhanced in the weak electric field limit when $m < \sqrt{2} H$.
description: revtex4, seven figures, no tables. JCAP 02 (2018) 018
Creating CHOIS: A Recovery-Oriented PROMIS-Based Measure for Mental Health Screening and Outcomes
Creators: name: Sarkin Andrew J
name: Sklar Marisa A
Publisher: name: figshare
Year: 2018
Subjects: subject: 111704 Community Child Health
subject: FOS: Health sciences

description: The National Institutes of Health Patient Reported Outcomes Medical Information System (PROMIS) measures a few important domains of mental health, but does not yet measure some other important psychiatric symptoms, nor does it include recovery factors and strengths such as social connectedness, self-esteem, and coping ability. The CHOIS is a recovery-oriented PROMIS-based instrument designed to supplement traditional PROMIS administration by attempting to fill in these gaps in mental health assessment. It was created for settings that do not primarily focus on mental health issues such as primary care, non-psychiatric hospitals, and substance abuse services. It adds specific symptoms of mental disorders based on DSM-IV-TR, positive recovery factors that were drawn from focus groups of people with mental illnesses, andresponse inconsistency indicators. We first implemented the measure across 13 Alcohol and Drug Services programs as a screening measure and outcomes tool, and measured internal consistency of the scales among a wide variety of participants. Among the 3,712 people who completed the measure, the internal consistency of the scales was as follows: Depression .93, Anxiety .89, Anger .87, Psychosis .79, Cognition .71, and Recovery Factors .90. All of the scales were significantly correlated with functional limitations and wanting help for mental health issues. The CHOIS could become an important tool for allowing valid and comprehensive immediate use of the still-developing PROMIS in a variety of settings as a mental health screening and outcomes instrument. It works seamlessly as a supplement to the entire PROMIS outcomes system that measures other important health constructs, and creates a more recovery-oriented focus for healthcare systems, even in non-psychiatric settings.
High Purcell factor generation of coherent on-chip single photons
Creators: name: Liu, F.
name: Brash, A. J.
name: O'Hara, J.
name: Martins, L. M. P. P.
name: Phillips, C. L.
name: Coles, R. J.
name: Royall, B.
name: Clarke, E.
name: Bentham, C.
name: Prtljaga, N.
name: Itskevich, I. E.
name: Wilson, L. R.
name: Skolnick, M. S.
name: Fox, A. M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: On-chip single-photon sources are key components for integrated photonic quantum technologies. Semiconductor quantum dots can exhibit near-ideal single-photon emission but this can be significantly degraded in on-chip geometries owing to nearby etched surfaces. A long-proposed solution to improve the indistinguishablility is by using the Purcell effect to reduce the radiative lifetime. However, until now only modest Purcell enhancements have been observed. Here we use pulsed resonant excitation to eliminate slow relaxation paths, revealing a highly Purcell-shortened radiative lifetime (22.7 ps) in a waveguide-coupled quantum dot-photonic crystal cavity system. This leads to near-lifetime-limited single-photon emission which retains high indistinguishablility (93.9%) on a timescale in which 20 photons may be emitted. Nearly background-free pulsed resonance fluorescence is achieved under $π$-pulse excitation, enabling demonstration of an on-chip, on-demand single-photon source with very high potential repetition rates.
description: Manuscript with 9 pages and 5 figures plus supplementary materials comprising 12 pages and 11 figures
Effect of Antenatal Services During Pregnancy on Prevalence of Anemia Amongst Pregnant Women in Lucknow
Creators: name: Mishra A
name: Mishra AN
Publisher: name: figshare
Year: 2018
Subjects: subject: 111704 Community Child Health
subject: FOS: Health sciences

description: Objective: To study the effect of antenatal care services (ANC) during pregnancy on prevalence of anemia amongst pregnant women in Lucknow. Study design: Cross-sectional study Study area: Urban and rural areas of Lucknow. Study subjects: A total of 455 pregnant women residing in urban and rural areas. Results: More than half (62.2%) of the pregnant women received ANC services at any health facility. The overall prevalence of anemia was 67.5%. Of these, the moderate anemia was 47.6%, mild was 43.6% and severe was 8.8%. The prevalence was almost similar in urban (73.3%) and rural (62.4%) pregnant women as well as in Hindu (64%) and Muslim (74.2%) women. Age at marriage did not affect in the prevalence of anemia among pregnant women. The education of women had significant association with the prevalence of anemia as the anemia was significantly (p<0.0001) higher in illiterate (81%) women than literates. Conclusion: The ANC service is still not at par, it is to be promoted that every pregnant woman should get ANC services in time. This will decrease the anaemia prevalence.
Reframing the Conversation: Understanding Socio-Economic Impact Assessments within the Cycles of Boom and Bust
Creators: name: Badenhorst CJ
name: Mulroy P
name: G, Thibault
name: Healy T
Publisher: name: figshare
Year: 2018
Subjects: subject: 111704 Community Child Health
subject: FOS: Health sciences

description: Socio-economic impact assessments (SEIA) are an essential step in identifying and evaluating the potential direct or indirect impacts of proposed economic developments, programs, and projects on communities. A SEIA provides a framework to address the changing demographics and the impacts on services and infrastructure, economic structures including employment and business opportunities, quality of life, the overall health and well-being of the population, and the cultural values of the community. Communities that host rapid industrial development often follow a predictable trajectory of rapid development, operational stability, and industry decline. This cycle known as the “boom and bust” cycle has significant implications on the sustainability of communities. With British Columbia on the cusp of significant industrial development, the Health Officers Council (HOC) of British Columbia in partnership with Northern Health, hosted a collaborative workshop to strategize about addressing the socio-economic impacts of proposed developments on communities. Through collaborative and open dialogue, collectively the group identified the key strategies in supporting to communities to maximize the benefits of development while mitigating the potentially negative socio-economic impacts.
Modellbasierter Entwurf und Optimierung mehrbeiniger Laufroboter
Creators: name: Rönnau, Arne
Publisher: name: Karlsruhe
Year: 2020
Subjects: Optimierung
Analyse
Metriken
mehrbeinige Lokomotion
Robotik
sechsbeiniger Laufroboter

description: Das mehrbeinige Laufen wirkt bei der Beobachtung von Insekten und Tieren so einfach und selbstverständlich. Gleichzeitig bietet es aber so viele konzeptionelle und robotische Herausforderungen. Dieser Widerspruch zwischen der hohen Komplexität des technischen Laufens gegenüber den natürlichen, einfachen Vorbildern fasziniert Forscher und Denker schon seit Jahrtausenden. Dennoch gibt es bis heute nur wenige Möglichkeiten die Fähigkeiten von einem Laufroboter auf einen anderen zu übertragen oder die Systeme auch nur miteinander zu vergleichen. Diese Arbeit ermöglicht es die Leistungsfähigkeit mehrbeiniger Laufroboter systematisch und zugleich systemunabhängig zu analysieren und gezielt weiterzuentwickeln. In einem ersten Schritt konnte die hierfür notwendige Abstraktion durch ein auf die wesentlichen Lokomotionskenngrößen reduziertes Lokomotionsmodell erreicht werden. Die Konzeption und Entwicklung dieses Modells bietet einen tiefen Einblick in die zentralen Gemeinsamkeiten der mehrbeinigen Lokomotion. Bei der Entwicklung neuer Laufroboter sowie dem anstehenden Transfer dieser Systeme in reale Anwendungen ergeben sich stets wiederkehrende Herausforderungen. Anhand dieser abgeleiteten Anforderungen konnten die wichtigsten, systemunabhängigen Leistungskenngrößen (Key Performance Indikatoren) für mehrbeinige Laufroboter identifiziert werden: Stabilität, Geschwindigkeit und Energieeffizienz. Auf Basis des abstrahierten Lokomotionsmodells konnten drei neue Laufroboter-Metriken entwickelt werden, die diese zentralen Leistungskriterien vergleichbar machen. Die systemunabhängigen Analyseverfahren basieren auf diesen Metriken und erlauben eine roboterunabhängige Bewertung sowie Identifikation von Best Practices. Die auf diesen Analysen aufbauenden und ihm Rahmen dieser Arbeit entwickelten Optimierungsverfahren sind in der Lage die Leistungsfähigkeit mehrbeiniger Laufrobotern erfolgreich zu steigern. Die experimentelle Evaluation der entwickelten Ansätze und Verfahren mit den sechsbeinigen Laufrobotern LAURON IVc und LAURON V konnte die positiven Effekte auf die Stabilität, Geschwindigkeit sowie Energieeffizienz nachweisen.
Art as Architecture: Abstract Modernist Painting Techniques and the Viewer Experience
Creators: name: McClure, Katherine
Publisher: name: Digital Repository at the University of Maryland
Year: 2023
Subjects: subject: Architecture
subject: FOS: Civil engineering
subject: Fine arts
subject: Abstract
subject: Architecture
subject: Artist
subject: Georgetown
subject: Painting
subject: Rothko

description: The reciprocal relationship between art and architecture has been a longstanding practice in the design process of both fields. The geometric forms, textures, and colors of various forms of art, but especially painting, have been known to inspire the architectural design process. Similarly, the shape and environmental experience of buildings can inspire or host works of art. Certain paintings, like those of Mark Rothko, are often cited in foundational architectural courses as examples of comprehensive and layered forms suggestive of architecture. However, these references are not typically taken beyond the parti phase in the early stages of architectural design. But how far can this reciprocal inspiration be taken? How can architecture evolve as not just a place for art, but as art itself? This thesis will explore the ways in which the abstract modernist painting techniques of the late works of Mark Rothko can affect the compositional form and experience of a mixed-use artist residency in Georgetown, DC.
Keyring models: an approach to steerability
Creators: name: Miller, Carl A.
name: Colbeck, Roger
name: Shi, Yaoyun
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: If a measurement is made on one half of a bipartite system, then, conditioned on the outcome, the other half has a new reduced state. If these reduced states defy classical explanation -- that is, if shared randomness cannot produce these reduced states for all possible measurements -- the bipartite state is said to be steerable. Determining which states are steerable is a challenging problem even for low dimensions. In the case of two-qubit systems a criterion is known for T-states (that is, those with maximally mixed marginals) under projective measurements. In the current work we introduce the concept of keyring models -- a special class of local hidden state models. When the measurements made correspond to real projectors, these allow us to study steerability beyond T-states. Using keyring models, we completely solve the steering problem for real projective measurements when the state arises from mixing a pure two-qubit state with uniform noise. We also give a partial solution in the case when the uniform noise is replaced by independent depolarizing channels.
description: 15(+4) pages, 5 figures. v2: references added, v3: minor changes
Exact Solutions for Restricted Incompressible Navier--Stokes Equations with Dirichlet Boundary Conditions
Creators: name: García-Casado, Manuel
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: This paper exposes how to obtain a relation that have to be hold for all free--divergence velocity fields that evolve according to Navier--Stokes equations. However, checking the violation of this relation requires a huge computational effort. To circumvent this problem it is proposed an additional antsatz to free-divergent Navier--Stokes fields. This makes available six degrees of freedom which can be tuned. When they are tuned adequately, it is possible to find finite $L^2$ norms of the velocity field for volumes of $\mathbb{R}^3$ and for $t\in[t_0,\infty)$. In particular, the kinetic energy of the system is bounded when the field components $u_i$ are class $C^3$ functions on $\mathbb{R}^3\times[t_0,\infty)$ that hold Dirichlet boundary conditions. This additional relation lets us conclude that Navier--Stokes equations with no-slip boundary conditions have not unique solution. Moreover, under a given external force the kinetic energy can be computed exactly as a funtion of time.
description: This is an author-created, un-copyedited version of an article published in Journal of Physics Communications. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. This article is published under a CC BY licence. The Version of Record is available online at https://doi.org/10.1088/2399-6528/ab3837
Epilepsy in Kashmir, J&K Childhood Seizures & Epilepsy, Types, Causes, Diagnosis, Intervention, Prevalence and Action
Creators: name: Ganaie S.A
name: A, Bashir
Publisher: name: figshare
Year: 2018
Subjects: subject: 111704 Community Child Health
subject: FOS: Health sciences

description: An epileptic seizure is a transient occurrence of signs and or symptoms due to abnormal excessive or synchronous neuronal activity in the brain. Epilepsy is a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures and by the neurobiological, cognitive, psychological, and social consequences of this condition. The definition of epilepsy requires the occurrence of at least one epileptic seizure (ILAE & IBE 2005). Epilepsy is a physical condition that occurs when there is a sudden, brief change in how the brain works. When brain cells are not working properly, a person's consciousness, movement, or actions may be altered for a short time. These physical changes are called epileptic seizures. Epilepsy is therefore sometimes called a seizure disorder. Epilepsy affects people in all nations and of all races (Epilepsy Foundation of America). The peak stages for the occurrence of epileptic disorders are Childhood and late adulthood as seen in developed countries but it has not been documented properly. The main causes are head injuries, cerebrovascular disease, CNS infections, and birth trauma. Availability of epilepsy-care depends largely on economic factors. Imaging and neurophysiological facilities are available in most countries, but often only in urban centres. Costly drugs, a large treatment gap, limited epilepsy surgery, and negative public attitude to epilepsy are other notable features of management in developing countries. An understanding of the psychosocial, cultural, economic, organizational and political factors influencing epilepsy causation, management, and outcome should be of high priority for future investigations. The lifetime prevalence of epilepsy varied among countries from 1•5 to 14•0 per 1000. This wide variation could partly result from the use of different methods and different types of questionnaire. Screening questionnaires were mainly derived from WHO questionnaires. The prevalence of epileptic disorders in India is 5.9 in males and 5.5 in females in the reference year of 1999. The Incidence of epileptic disorders in India is 60 out of 100,000 in the reference year of 199.
Reprogramming astroglia into neurons with hallmarks of fast-spiking parvalbumin-positive interneurons by phospho-site-deficient Ascl1.
Creators: name: Marichal, Nicolás
name: Péron, Sophie
name: Arranz, Ana Beltrán
name: Galante, Chiara
name: Scarante, Franciele Franco
name: Wiffen, Rebecca
name: Schuurmans, Carol
name: Karow, Marisa
name: Gascón, Sergio
name: Berninger, Benedikt
Publisher: name: The Francis Crick Institute
Year: 2024
Subjects: classificationCode: Developmental Biology
subject: Developmental Biology
classificationCode: Computational & Systems Biology
subject: Computational & Systems Biology
classificationCode: Model organisms
subject: Model organisms
classificationCode: Cell Biology
subject: Cell Biology
classificationCode: Imaging
subject: Imaging

description: Cellular reprogramming of mammalian glia to an induced neuronal fate holds the potential for restoring diseased brain circuits. While the proneural factor achaete-scute complex-like 1 (Ascl1) is widely used for neuronal reprogramming, in the early postnatal mouse cortex, Ascl1 fails to induce the glia-to-neuron conversion, instead promoting the proliferation of oligodendrocyte progenitor cells (OPC). Since Ascl1 activity is posttranslationally regulated, here, we investigated the consequences of mutating six serine phospho-acceptor sites to alanine (Ascl1SA6) on lineage reprogramming in vivo. Ascl1SA6 exhibited increased neurogenic activity in the glia of the early postnatal mouse cortex, an effect enhanced by coexpression of B cell lymphoma 2 (Bcl2). Genetic fate-mapping revealed that most induced neurons originated from astrocytes, while only a few derived from OPCs. Many Ascl1SA6/Bcl2-induced neurons expressed parvalbumin and were capable of high-frequency action potential firing. Our study demonstrates the authentic conversion of astroglia into neurons featuring subclass hallmarks of cortical interneurons, advancing our scope of engineering neuronal fates in the brain.
APPETItE - Ecological Momentary Analysis
Creators: name: Pickard, Abigail
name: Blissett, Jacqueline
name: Farrow, Claire
name: Edwards, Katie
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Public Health
subject: Medicine and Health Sciences
subject: Life Sciences
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Avid eating
subject: Children's eating behaviour
subject: EMA
subject: ESM
subject: Ecological Momentary Assessment
subject: Parental Feeding Practices

description: An understanding of feeding behaviours and their motivational context is critical to understand the variety of outcomes in the parental feeding literature and to develop effective parental interventions for child obesity prevention. This ecological momentary assessment will examine ‘in the moment’ feeding behaviours, emotions, and cognitions experienced by primary caregivers of preschool children with avid eating behaviour. Examining feeding interactions as they occur in real time and real contexts using EMA will provide insight into primary caregivers’ experiences of feeding their child with avid eating behaviour.
A Study on Challenges & Prospects of A Construction Equipment operator Training : The Case of Alemgena Machine - Based Technology Training center ( AMBTTC )
Creators: name: Muhammed, Kayo
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2022
Subjects: Challenge, Need assessment, Training, Curriculum, Cooperative.

description: This study was aimed at assessing the challenges and prospects of construction equipment
 operators training at Alemgena Machine- Base Technology Training Center (AMBTTC). To
 achieve this, descriptive research design with quantitative research approach was adopted.
 Quantitative data obtained through questionnaire. Using probability sampling design,
 sample respondents of trainers and current trainees were selected from targeted population
 by applying simple random sampling technique. Non-probability sampling design was
 applied to select respondents from graduated trainees.By integrating the interview data
 analysis from Training Center Manager and Engineering and Equipment Operation
 Training Team Leader, the data were analyzed in the form of frequency, mean and standard
 deviation. The major findings of the study indicated that, the training center is not
 conducting training according to TVET premises demand based training. The training
 curriculum is not feasible and lacks modernity. Antagonistically to its adequacy in training
 Equipment and facility, the training center is not in a position to coordinate all its resources
 to produce competent equipment operator. Even though TVET led cooperative training
 mode supposed to be deliver equipment operation training by shared responsibilities of
 TVET institution/training center and enterprises/stakeholders, they were not in expected
 position to deliver training mode. Finally; as the finding showed AMBTTC has prospects of
 being effective TVET institution. The training center needs to conduct holistic and
 professional demand assessment. With participation of all stakeholders training curriculum
 needs to be revised with current context of training center. Besides building its capacity to
 deliver current training curriculum, the training center supervisors have work with
 stakeholders to realize the implementation of cooperative training
К ВОПРОСУ ОБ ИСКЛЮЧИТЕЛЬНОМ ПРАВОВОМ ПОЛОЖЕНИИ НОВГОРОДСКОГО ВЛАДЫКИ И ЕГО ЦЕРКОВНО-ПОЛИТИЧЕСКАЯ РОЛЬ В ДРЕВНЕРУССКОМ ГОСУДАРСТВЕ
Creators: name: Руслан Маратович Ахмедов
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: государство
церковь
право
Новгород
Москва
Русь

description: Статус новгородского владыки соответствовал духу времени и тем политико-правовым процессам, которые протекали в Новгородской феодальной республике. Став во главе государственного «кормила», епископ, в лице владельца Святого Дома Софии, отображал церковно-политические свободы и права вольного города, его характер и внутренние отношения. Однако централизация удельных земель под сильной «рукой» Московского государя, изменила привычный ход церковно-политических событий в новгородской земле, которая в конце XV в. подчинилась церковно-политической администрации формируемого единого Русского государства.
A qualitative exploration of young adults’ perceptions of a new intervention for alcohol use disorder
Creators: name: Hallihan, Hagar
name: Abboud, Sarah
name: Lee, Sangeun
name: Rospenda, Kathleen
name: Srimoragot, Manassawee
name: Fink, Anne
name: Ma, Jun
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Due to the rising prevalence of alcohol use disorders among young adults, the need for effective and accessible interventions has become increasingly imperative. In acknowledgment of this issue, we developed a novel intervention known as contingency management plus problem solving therapy (CM-PST). The aim of the current study was to gain insight into the perspectives on the effectiveness of the newly developed CM-PST using focus group discussion among young adults who consume alcohol regularly. The study employed a qualitative research design, utilizing focus group discussions as the primary data collection method. Participants described their perceptions regarding the newly developed CM-PST. Semi-structured focus group sessions were conducted via Zoom in November 2022. A total of 19 young adults, aged 18-24 years old, participated in five focus group sessions. Data were analyzed using deductive content analysis. Participants demonstrated overall positive attitudes toward the novel intervention, recognizing the potential benefits, it could offer in terms of alcohol use reduction and emotional well-being. They emphasized the importance of incentives in motivating behavioral changes, as well as the practicality of problem-solving techniques in addressing everyday challenges. Additionally, participants provided valuable insights into potential barriers and implementation challenges, highlighting the need for flexible and personalized approaches to accommodate individual preferences and needs. The results of this study contribute to the growing body of literature on innovative intervention approaches for young adults facing alcohol use issues. The findings shed light on the acceptability and perceived effectiveness of the CM-PST intervention from the perspective of the target population.
Is standing balance altered in individuals with chronic low back pain? A systematic review
Creators: name: Berenshteyn, Yevgeniy
name: Gibson, Kelsey
name: Hackett, Gavin C.
name: Trem, Andrew B.
name: Wilhelm, Mark
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Purpose: To examine the static standing balance of individuals with chronic low back pain when compared to a healthy control group. Methods: A search of available literature was done using PubMed, SPORTDiscus, CINAHL, and Scopus databases. Studies were included if they contained the following: (1) individuals with chronic low back pain 3 months or longer; (2) healthy control group; (3) quantified pain measurement; and (4) center of pressure measurement using a force plate. Two authors independently reviewed articles for inclusion, and assessed for quality using the Joanna Briggs Institute Critical Appraisal Checklist for Analytical Cross Sectional Studies. Cohen’s d effect size was calculated to demonstrate the magnitude of differences between groups. Results: Nine articles were included in this review. Quality scores ranged from 5/8 to 8/8. Although center of pressure measures were nonhomogeneous, subjects with chronic low back pain had poorer performance overall compared to healthy controls. Despite inconsistencies in statistical significance, effect sizes were frequently large, indicating a lack of sufficient power in the included studies. Data were insufficiently reported among certain studies, limiting the ability of direct study comparison. Conclusions: Results suggest that balance is impaired in individuals with chronic low back pain when compared to healthy individuals. Implications for rehabilitationStatic balance is affected in individuals with chronic low back pain.Balance assessments should be completed for individuals with chronic low back pain.Results from balance assessments should be used to indicate areas of improvement and help guide the course of treatment, as well as reassess as treatment progresses. Static balance is affected in individuals with chronic low back pain. Balance assessments should be completed for individuals with chronic low back pain. Results from balance assessments should be used to indicate areas of improvement and help guide the course of treatment, as well as reassess as treatment progresses.
Target Patterns in a 2-D Array of Oscillators with Nonlocal Coupling
Creators: name: Jaramillo, Gabriela
name: Venkataramani, Shankar
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: Functional Analysis (math.FA)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We analyze the effect of adding a weak, localized, inhomogeneity to a two dimensional array of oscillators with nonlocal coupling. We propose and also justify a model for the phase dynamics in this system. Our model is a generalization of a viscous eikonal equation that is known to describe the phase modulation of traveling waves in reaction-diffusion systems. We show the existence of a branch of target pattern solutions that bifurcates from the spatially homogeneous state when $\varepsilon$, the strength of the inhomogeneity, is nonzero and we also show that these target patterns have an asymptotic wavenumber that is small beyond all orders in $\varepsilon$. The strategy of our proof is to pose a good ansatz for an approximate form of the solution and use the implicit function theorem to prove the existence of a solution in its vicinity. The analysis presents two challenges. First, the linearization about the homogeneous state is a convolution operator of diffusive type and hence not invertible on the usual Sobolev spaces. Second, a regular perturbation expansion in $\varepsilon$ does not provide a good ansatz for applying the implicit function theorem since the nonlinearities play a major role in determining the relevant approximation, which also needs to be "correct" to all orders in $\varepsilon$. We overcome these two points by proving Fredholm properties for the linearization in appropriate Kondratiev spaces and using a refined ansatz for the approximate solution, which obtained using matched asymptotics.
description: 39 pages, 1 figure
Examining Interindividual Differences in Unemployment-Related Changes in Subjective Well-Being: The Role of Psychological Well-Being and Re-Employment Expectations
Creators: name: Lawes, Mario
name: Eid, Michael
Publisher: name: OSF
Year: 2021

description: Online Repository for the manuscript "Examining interindividual differences in unemployment-related changes in subjective well-being: The role of psychological well-being and re-employment expectations" (in press at European Journal of Personality)
title: ADCO, Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Cart. 181 (11 H 754), 165 folios, f. 0304
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 181 (11 H 754), 165 folios, f. 0304, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 181 (11 H 754), 165 folios, f. 0304, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
О КОНСТИТУЦИОННОМ И МУНИЦИПАЛЬНОМ ПРАВЕ
Creators: name: Владимир Сергеевич Дурнев
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: прогнозирование
конституционное право
муниципальное право
предмет правового регулирования
муниципальная власть
местное самоуправление

description: Рассматриваются некоторые подходы к пониманию конституционного и муниципального права, в том числе в их соотношении друг с другом, а также вопросы описания института муниципальной власти (местного самоуправления) в рамках конституционного права для нужд прогностических исследований.
ОСОБЕННОСТИ ПРАВОВОГО ПОЛОЖЕНИЯ ИНОСТРАННЫХ ГРАЖДАН И ЛИЦ БЕЗ ГРАЖДАНСТВА В ПЕРИОД ВВЕДЕНИЯ ЧРЕЗВЫЧАЙНОГО ПОЛОЖЕНИЯ НА ТЕРРИТОРИИ РОССИЙСКОЙ ФЕДЕРАЦИИ ИЛИ В ОТДЕЛЬНЫХ ЕЕ МЕСТНОСТЯХ
Creators: name: Олег Валентинович Зиборов
name: Сергей Олегович Харламов
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: иностранные граждане
лица без гражданства
чрезвычайное положение
интернирование
меры административного принуждения

description: Чрезвычайное положение означает вводимый на всей территории Российской Федерации или в ее отдельных местностях особый правовой режим деятельности органов государственной власти, органов местного самоуправления, организаций независимо от организационно-правовых форм и форм собственности, их должностных лиц, общественных объединений, допускающий установленные настоящим Федеральным конституционным законом отдельные ограничения прав и свобод граждан Российской Федерации, иностранных граждан, лиц без гражданства, прав организаций и общественных объединений, а также возложение на них дополнительных обязанностей. Значимое место занимают меры, являющиеся юридическими фактами для возникновения новых групп общественных отношений, существование которых не предусматривается при мирном течении общественной жизни. К таким чрезвычайным мерам относятся: интернирование (изоляция) иностранных граждан воюющего с Российской Федерацией государства, введение военной цензуры за почтовыми отправлениями и сообщениями и иные виды мер. Под интернированием понимается принудительное задержание, переселение или иное ограничение свободы передвижения, устанавливаемое одной воюющей стороной для находящихся на ее территории граждан другой воюющей стороны или для граждан другой воюющей стороны, находящихся на оккупированной первой воюющей стороной территории, или нейтральным государством для военнослужащих воюющих сторон.
Is standing balance altered in individuals with chronic low back pain? A systematic review
Creators: name: Berenshteyn, Yevgeniy
name: Gibson, Kelsey
name: Hackett, Gavin C.
name: Trem, Andrew B.
name: Wilhelm, Mark
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Purpose: To examine the static standing balance of individuals with chronic low back pain when compared to a healthy control group. Methods: A search of available literature was done using PubMed, SPORTDiscus, CINAHL, and Scopus databases. Studies were included if they contained the following: (1) individuals with chronic low back pain 3 months or longer; (2) healthy control group; (3) quantified pain measurement; and (4) center of pressure measurement using a force plate. Two authors independently reviewed articles for inclusion, and assessed for quality using the Joanna Briggs Institute Critical Appraisal Checklist for Analytical Cross Sectional Studies. Cohen’s d effect size was calculated to demonstrate the magnitude of differences between groups. Results: Nine articles were included in this review. Quality scores ranged from 5/8 to 8/8. Although center of pressure measures were nonhomogeneous, subjects with chronic low back pain had poorer performance overall compared to healthy controls. Despite inconsistencies in statistical significance, effect sizes were frequently large, indicating a lack of sufficient power in the included studies. Data were insufficiently reported among certain studies, limiting the ability of direct study comparison. Conclusions: Results suggest that balance is impaired in individuals with chronic low back pain when compared to healthy individuals.Implications for rehabilitationStatic balance is affected in individuals with chronic low back pain.Balance assessments should be completed for individuals with chronic low back pain.Results from balance assessments should be used to indicate areas of improvement and help guide the course of treatment, as well as reassess as treatment progresses. Static balance is affected in individuals with chronic low back pain. Balance assessments should be completed for individuals with chronic low back pain. Results from balance assessments should be used to indicate areas of improvement and help guide the course of treatment, as well as reassess as treatment progresses.