cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Filtration efficiency analysis of fibrous filters: Experimental and theoretical study on the sampling of agglomerate particles emitted from a GDI engine
Creators: name: Chen, Longfei
name: Ding, Shirun
name: Liang, Zhirong
name: Zhou, Lei
name: Zhang, Hongxing
name: Zhang, Cuiqi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Fibrous filters are commonly used for aerosol purification and sampling. The filtration efficiency has been extensively studied using standard aerosol generators, yet the literature on experimental data and theoretical study concerning the filtration of agglomerates from real engines remains scarce. A filtration efficiency test system was developed to determine the filtration efficiency of two types of filters (uncoated and fluorocarbon coated) loaded by particulate matter (PM) emissions from a gasoline direct injection (GDI) engine. The experimental results showed that the filtration efficiency in terms of PM mass and number increased over time for both types of filters. The fractional efficiency (penetration efficiency) curves for the test fibrous filters rendered a U-shaped curve for particle sizes from 70 to 500 nm, and the most penetrating particulate size (MPPS) decreased over time. A small fraction of accumulation mode particles with the size between 70 nm to 500 nm penetrated the filters while almost all nucleation mode particles with the size below 50 nm were captured by the filters. The filtration efficiency derived from an empirical model based on classical single-fiber theory for laden filters generally agreed with the experimental data for the first 500 s, but suffered a significant deviation by approximately one order of magnitude at 948 s. A better estimate of the filtration efficiency trend with the maximum deviation of about 20% (except for large particles at the high end of the measurement spectra) was obtained by using a revised model which incorporates the effects of the increase in filter solidity, local velocity, dynamic shape factor and effective total length of fibers during the filtration process. © 2017 American Association for Aerosol Research
INASP survey final.pdf
Creators: name: Bezuidenhout, Louise
name: Ereck Chakauya
Publisher: name: figshare
Year: 2017
Subjects: subject: Sociology
subject: FOS: Sociology

description: The Open Science movement is changing the way in which research is conducted. Increasingly, the ability to disseminate and re-use research data are becoming hallmarks of how scientific research are conducted. This movement towards openness is underpinned by strong egalitarian commitments that emphasize the importance of data to be accessible to all scientists - regardless of funding, nationality or geographic location. While this egalitarian commitment cannot be faulted in principle, in practice it is possible that the focus on providing equal access to online resources masks important differentiations in scientists’ ability to effectively use the available resources. In particular, we must question whether the research environments of scientists in low/middle-income countries offer significant barriers to the effective engagement with online resources. These issues were qualitatively examined in a previous study involving scientists in South Africa and Kenya, during which a number of seemingly innocuous aspects of research environments were identified by research participants as key barriers to their online data engagement activities. In this study we extended these qualitative findings by rolling out a quantitative survey to scientists within the 13 countries involved in the Southern African Network for the Biosciences (NEPAD SANBio). Through this survey we hope to generalize the qualitative findings and initiate robust discussion on how best to structure future OS initiatives aimed at improving capacity or networking within the sub-Saharan African region. It will be an important contribution to furthering the knowledge and information sharing objectives of NEPAD SANBio.
Spin-down of a pulsar with a yielding crust
Creators: name: Sob'yanin, Denis Nikolaevich
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Nuclear Theory (nucl-th)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: In light of the discovery of the long-period radio pulsar PSR J0901-4046, it is interesting to revisit a question about how the magnetized neutron star slows down its rotation. In the case of a weak or liquid outer crust, the mechanism of spin-down becomes unclear because the braking stress cannot then be transmitted from the surface to the main bulk of the star. We show that even if the outer crust does not withstand the surface electromagnetic forces creating the braking torque, the stellar spin-down does not stop, and the matter rearranges so that the necessary electromagnetic forces form in more deep and rigid layers capable of withstanding these forces. The spin-down rate remains the same and corresponds to the transformation of the rotational energy of the neutron star into the energy of the generated relativistic electron-positron plasma. The solid iron surface of ultrastrongly magnetized PSR J0901-4046 appears not to be yielding and withstands the braking stress without breaking.
description: 5 pages, 1 figure
title: Conductivity of Insulating Diblock Copolymer System Filled with Conductive Particles Having Different Affinities for Dissimilar Copolymer Blocks
Creators: name: Chervanyov, Alexander
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2022
Subjects: subject: 530 Physics

description: We investigate the electrical response of the insulating diblock copolymer system (DBC) filled with conductive spherical fillers depending on the affinities of these fillers for copolymer blocks and the interaction between fillers. We demonstrate that the contrast (difference) between the affinities of the fillers for dissimilar copolymer blocks is a decisive factor that determines the distribution of these fillers in the DBC system. The distribution of filler particles, in turn, is found to be directly related to the electrical response of the DBC-particle composite. In particular, increasing the affinity contrast above a certain threshold value results in the insulator-conductor transition. This transition is found to be caused by the preferential localization of the fillers in the microphases of the DBC system having larger affinity for these fillers. The effect of the interaction between fillers is found to be secondary to the described effect of the affinity contrast that dominates in determining the distribution of fillers in the composite. This effect of the inter-particle interactions is shown to be significant only when the affinity contrast and filler volume fraction are sufficiently large.
description: Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Antimicrobial activity and molecular docking studies of a novel anthraquinone from a marine-derived fungus Aspergillus versicolor
Creators: name: Wang, Weiyi
name: Chen, Ruixuan
name: Luo, Zhuhua
name: Wang, Wei
name: Chen, Jianming
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Virology

description: A novel anthraquinone, 2-(dimethoxymethyl)-1-hydroxyanthracene-9,10-dione (1), together with nine known compounds (2–10), were isolated from the fermentation of Aspergillus versicolor derived from deep sea sediment. Their structures were established through spectroscopic methods. Compound 1 exhibited strong inhibitory activities against MRSA ATCC 43300 and MRSA CGMCC 1.12409 (with MIC values of 3.9 and 7.8 μg/mL respectively) and moderate activities against tested strains of Vibrio (with MIC values ranging from 15.6 to 62.5 μg/mL). Compound 1 was subjected to molecular docking studies for inhibition of topoisomerase IV and AmpC β-lactamase enzymes indicating its usefulness as antimicrobial agent.
title: 01_0720
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Coordination diversity in palladium(II)-picolinamide ligand complexes: Structural and quantum chemical studies
Creators: name: Das, Debasish
name: Amsaveni Muruganantham
name: S. Kannan
name: Kumar, Mukesh
name: Sundararajan, Mahesh
name: M.K. Sureshkumar
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: The separation of different metal ions can be successfully accomplished by using picolinamide-based ligands. We herein report the first X-ray structure of picolinamide-based ligands of the type C5H4NCONR2 (where R = iC3H7 (L1) and iC4H9 (L2)) and C5H4NCONHR (R = tC4H9 (L3)) with palladium(II) ion. We have synthesized and characterized the structures of two palladium complexes, [PdCl2(L1)2] (1) and [PdCl2L3] (3). In 1, ligand L1 forms a 2:1 complex with palladium(II) chloride, whereas in 3, the ligand L3 forms a 1:1 complex. Further, in 1, the ligand L1 acts as a monodentate ligand and is bound only through pyridyl-N atom, whereas in 3, the ligand L3 acts as a bidentate chelating ligand and is bound through both the pyridyl-N and amido-O atoms to the Pd(II) center. Electronic structure calculations are carried out to understand the experimental coordination diversity in the Pd complexes. Our calculations clearly suggest that a combination of steric hindrance of the ligand and the electronic effect of metal ions may modulate the coordination preferences.
GroundGrid:LiDAR Point Cloud Ground Segmentation and Terrain Estimation
Creators: name: Steinke, Nicolai
name: Göhring, Daniel
name: Rojas, Raùl
Publisher: name: arXiv
Year: 2024
Subjects: subject: Robotics (cs.RO)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: The precise point cloud ground segmentation is a crucial prerequisite of virtually all perception tasks for LiDAR sensors in autonomous vehicles. Especially the clustering and extraction of objects from a point cloud usually relies on an accurate removal of ground points. The correct estimation of the surrounding terrain is important for aspects of the drivability of a surface, path planning, and obstacle prediction. In this article, we propose our system GroundGrid which relies on 2D elevation maps to solve the terrain estimation and point cloud ground segmentation problems. We evaluate the ground segmentation and terrain estimation performance of GroundGrid and compare it to other state-of-the-art methods using the SemanticKITTI dataset and a novel evaluation method relying on airborne LiDAR scanning. The results show that GroundGrid is capable of outperforming other state-of-the-art systems with an average IoU of 94.78% while maintaining a high run-time performance of 171Hz. The source code is available at https://github.com/dcmlr/groundgrid
description: This letter has been accepted for publication in IEEE Robotics and Automation Letters
Atomistic investigation of homogeneous nucleation in undercooled liquid
Creators: name: Guo, Can
name: Wang, Jincheng
name: Wang, Zhijun
name: Li, Junjie
name: Huang, Yunhao
name: Tang, Sai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Although nucleation, a fundamental physical phenomenon in nature, has long been studied by simulations and experiments, our knowledge of this process is still quite limited. Herein, the atomistic pathways of homogeneous nucleation are studied using the phase-field crystal model. We find that nucleation is of one-step type for low initial densities (solid volume fraction), whereas two-step nucleation (TS) dominates in other cases. For the TS process, the fraction and the lifetime of metastable intermediate phases will increase with increasing density, and these metastable phases can significantly accelerate the nucleation process. By calculating the nucleation barriers, we investigated the origin of the appearance of the metastable phases and the mechanism of two-step nucleation.
Disposition and metabolism of [14C]-galunisertib, a TGF-βRI kinase/ALK5 inhibitor, following oral administration in healthy subjects and mechanistic prediction of the effect of itraconazole on galunisertib pharmacokinetics
Creators: name: Cassidy, Kenneth C.
name: Gueorguieva, Ivelina
name: Miles, Colin
name: Rehmel, Jessica
name: Yi, Ping
name: J. Ehlhardt, William
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Virology

description: 1. The disposition and metabolism of galunisertib (LY2157299 monohydrate, a TGF-βRI Kinase/ALK5 Inhibitor) was characterized following a single oral dose of 150 mg of [14C]-galunisertib (100 µCi) to six healthy human subjects. 2. The galunisertib plasma half-life was 8.6 h, while the 14C half-life was 10.0 h. Galunisertib was abundant in circulation (40.3% of the 14C AUC024 h), with 7 additional metabolites detected in plasma. Two metabolites LSN3199597 (M5, mono-oxidation), and M4 (glucuronide of M3) were the most abundant circulating metabolites (10.7 and 9.0% of the 14C AUC024 h respectively). The pharmacological activity of LSN3199597 was tested and found to be significantly less potent than galunisertib. 3. The dose was recovered in feces (64.5%) and in urine (36.8%). Galunisertib was cleared primarily by metabolism, based on low recovery of parent in excreta (13.0% of dose). Due to the slow in vitro metabolism of galunisertib in suspended hepatocytes, a long term hepatocyte system was used to model the human excretion profile. 4. Expressed cytochromes P450 and hepatocytes indicated clearance was primarily CYP3A4-mediated. Mechanistic static modeling that incorporated small non-CYP-mediated metabolic clearance and renal clearance components predicted an AUC ratio of 4.7 for the effect of itraconazole, a strong CYP3A4 inhibitor, on galunisertib.
Three new indole alkaloid derivatives from the roots of Murraya paniculata
Creators: name: Wang, Xiao-Ting
name: Zeng, Ke-Wu
name: Zhao, Ming-Bo
name: Tu, Peng-Fei
name: Li, Jun
name: Jiang, Yong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Three new indole alkaloid derivatives, named paniculidines D‒F (1‒3), and six known analogs (4‒9) were isolated from the roots of Murraya paniculata. The structures were elucidated on the basis of comprehensive HRESIMS, UV, IR, and NMR spectroscopic data analysis and comparison with the data reported in literature. The absolute configurations of new compounds were assigned via the determination of specific optical rotation, Mosher′s method, and ECD spectra. Compound 3 is the first heterodimer of C-N linked indole and coumarin derivatives.
Inverse method for quantitative characterisation of breast tumours from surface temperature data
Creators: name: R. Hatwar
name: C. Herman
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology

description: Purpose: We introduce a computational method to simultaneously estimate size, location and blood perfusion of the cancerous breast lesion from the surface temperature data. Methods: A 2D computational phantom of axisymmetric tumorous breast with six tissue layers, epidermis, papillary dermis, reticular dermis, fat, gland, muscle layer and spherical tumour was used to generate surface temperature distribution and thereby estimate tumour characteristics iteratively using an inverse algorithm based on Levenberg–Marquardt method. In addition to the steady state temperature data, we modified and expanded the inverse algorithm to include transient data that can be captured by dynamic infra-red imaging. Several test cases were considered for the transient analysis, where the depth, radii and blood perfusion of tumour were varied from 11 to 30 mm, 7 to 11 mm and 0.003 to 0.01 1/s, respectively. Results: Similar steady state temperature profile for different tumours makes it impossible to simultaneously estimate blood perfusion, size and location of tumour using steady state data alone. This becomes possible when transient data are used along with steady state data. For the cases discussed here, the estimates have errors below 1% for tumours with depths less than 20 mm, but for deeper tumours (25 mm) errors can be more than 10%. Conclusions: Combination of transient data and steady state data makes it possible to simultaneously estimate tumour size, location and blood perfusion. Blood perfusion is an indicator of the growth rate of the tumour and therefore its evaluation can possibly lead to the assessment of tumour malignancy.
Supplementary Information for "Metric clusters in evolutionary games on scale-free networks"
Creators: name: Kleineberg, Kaj Kolja
Publisher: name: figshare
Year: 2017
Subjects: subject: 29902 Complex Physical Systems
subject: FOS: Physical sciences

description: Supplementary Information for "Spatial clustering and heterogeneity in evolutionary games on structured populations: a unified framework"
Synthesis of SMND-309, a derivate of salvianolic acid B
Creators: name: Wu, Kong
name: Song, Chan
name: Cui, Dong-Mei
name: Zhang, Chen
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine

description: (E)-2-(6-((E)-2-carboxyvinyl)-2,3-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl) acrylic acid, designated SMND-309, was synthesized starting from 2-hydroxy-3-methoxybenzaldehyde in 12 steps and with an overall yield of 44%. The synthetic key features were the conversion of aryl aldehyde into aryl acetic acid for one-carbon extended, the Perkin condensation, and the Heck coupling for construction of α,β-unsaturated ester.
Palynological studies of melliferous and allergenic flora of Pakistan: A key to pollen and spore identification
Creators: name: Mehwish Jamil Noor
name: Ahmad, Mushtaq
name: Zafar, Muhammad
name: Ashraf, Muhammad Aqeel
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: This is the first reported study aimed to develop an identification key for pollen and spores of the melliferous and allergenic flora of Pakistan. Extensive field trips were conducted to collect the honey and allergenic pollen samples. The results present significant data on allergenic and melliferous palynological flora using morphological features of pollen on the bases of LM and SEM analyses. Pollen sculpturing along with detailed qualitative information is employed to build up an identification key for melliferous and allergenic pollen flora of Pakistan. Some characteristic pollen images are presented to classify the pollen types to family, genus or even species level wherever possible. This study provides significant information, to arrange the pollen types within their defined classes and to discuss various pollen features for developing a potential melliferous and allergenic pollen atlas.
Synthesis of SMND-309, a Derivate of Salvianolic Acid B
Creators: name: Wu, Kong
name: Song, Chan
name: Cui, Dong-Mei
name: Zhang, Chen
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine

description: (E)-2-(6-((E)-2-carboxyvinyl)-2,3-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl) acrylic acid, designated SMND-309, was synthesized starting from 2-hydroxy-3-methoxybenzaldehyde in 12 steps and with an overall yield of 44%. The synthetic key features were the conversion of aryl aldehyde into aryl acetic acid for one-carbon extended, the Perkin condensation, and the Heck coupling for construction of α,β-unsaturated ester.
Copper-catalyzed amidation of benzoic acids using tetraalkylthiuram disulfides as amine sources
Creators: name: Zeng, Meng-Tian
name: Xu, Wan
name: Liu, Min
name: Liu, Xing
name: Chang, Cai-Zhu
name: Zhu, Hui
name: Dong, Zhi-Bing
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Plant Biology
subject: Computational Biology

description: A facile method for the copper-catalyzed synthesis of N-substituted benzamides was explored. In the presence of CuBr and di-tert-butyl peroxide, various N-substituted benzamides were prepared through amidation of benzoic acid by using commercially available and cheap tetraalkylthiuram disulfides as amine sources. With this protocol, a series of 14 N-substituted benzamides were furnished in good to excellent yields. The broad substrate scope and good to excellent yield show its practical synthetic value in organic synthesis.
Copper-Catalyzed Amidation of Benzoic Acids Using Tetraalkylthiuram Disulfides as Amine Sources
Creators: name: Zeng, Meng-Tian
name: Xu, Wan
name: Liu, Min
name: Liu, Xing
name: Chang, Cai-Zhu
name: Zhu, Hui
name: Dong, Zhi-Bing
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Plant Biology
subject: Computational Biology

description: A facile method for the copper-catalyzed synthesis of N-substituted benzamides was explored. In the presence of CuBr and DTBP(di-tert-butyl peroxide), various N-substituted benzamides were prepared through amidation of benzoic acid by using commercially available and cheap tetraalkylthiuram disulfides as amine sources. With this protocol, a series of 14 N-substituted benzamides were furnished in good to excellent yields. The broad substrate scope and good to excellent yield show its practical synthetic value in organic synthesis.
Preemptive analgesia by using celecoxib combined with tramadol/APAP alleviates post-operative pain of patients undergoing total knee arthroplasty
Creators: name: Xu, Zhongwei
name: Zhang, Hua
name: Luo, Jiao
name: Zhou, Aiguo
name: Zhang, Jian
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Virology

description: Objective: This study was aimed to evaluate the efficacy of preemptive analgesia (PA) by using celecoxib combined with low-dose tramadol/acetaminophen (tramadol/APAP) in treating post-operative pain of patients undergoing unilateral total knee arthroplasty (TKA). Methods: A total of 132 patients scheduled for TKA were included in this study. Three-day pre-operative medication was administrated in PA group with subsequent effective intra- and post-operative multimodal analgesia, while control patients received multimodal analgesia without PA. Visual analog scale (VAS) was utilized to assess the pain intensity at rest and during movement. VAS scores of participants were recorded 3 days before surgery, 1 day, 3 days, 1 week, 3 weeks, 6 weeks, 3 months, 6 months, and 12 months postoperatively. Moreover, the length of hospital stay, expense of hospitalization, C-reactive protein (CRP) values during hospitalization, and complications during medication were also recorded. Results: PA showed superiority over control at 3 weeks (P = 0.013) and 6 weeks (P = 0.046) in resting pain, and 1 week (P = 0.015), 3 weeks (P = 0.003), 6 weeks (P = 0.003) and 3 months (P = 0.012) postoperatively in movement pain. There was no statistically significant difference in the length of hospital stay, total expense, CRP values, as well as complications. Conclusions: Based on satisfactory intra- and post-operative analgesia, PA by 3-day administration of celecoxib and low-dose tramadol/APAP might be an effective and safe therapy regarding patients undergoing TKA in terms of alleviating post-operative pain.
Functional brain alterations during self-reference processing in adolescents with sexual abuse-related post-traumatic stress disorder: A preliminary report
Creators: name: Dégeilh, Fanny
name: Viard, Armelle
name: Guénolé, Fabian
name: Gaubert, Malo
name: Pierre-Jean Egler
name: Egret, Stéphanie
name: Gerardin, Priscille
name: Jean-Marc Baleyte
name: Eustache, Francis
name: Dayana, Jacques
name: Guillery-Girard, Bérengère
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: We proposed to explore the functional brain changes during a self-reference processing (SRP) task in adolescents with sexual abuse-related post-traumatic stress disorder (N = 10), compared with healthy adolescents (N = 10). While patients showed no behavioral disturbances in (SRP), they exhibited changes in activity and connectivity in regions involved in emotional regulation (amygdala and dorsal prefrontal cortex) and semantic memory (temporal and ventrolateral prefrontal regions). These preliminary results suggest that these alterations may have an effect on self-esteem which may contribute to a possible retention and impairment of symptoms in adulthood.
Variations in abundance and community composition of denitrifying bacteria during a cyanobacterial bloom in a eutrophic shallow lake in China
Creators: name: Zhang, Weiguo
name: Gao, Yan
name: Yi, Neng
name: Wang, Chengcheng
name: Di, Panpan
name: Yan, Shaohua
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Although cyanobacterial blooms can change microbial communities, it is still unclear what impact such harmful blooms will have on denitrifying bacteria, the drivers of the removal of excessive nitrogen from water. In order to clarify the impact, populations of denitrifying bacteria, with periodic proliferation and dominance of cyanobacteria in a eutrophic shallow lake located in southeast China, were investigated using quantitative real-time polymerase chain reaction (qPCR) and 454-pyrosequencing based on the copper-containing nitrite reductase (nirK) gene, cytochrome cd1-containing nitrite reductase (nirS) gene and nitrous oxide reductase (nosZ) gene. Samples were collected periodically during a three-month period when the cyanobacterial density gradually increased. In the qPCR analyses, abundances of nirK, nirS and nosZ were intensely positively correlated with the biomass of cyanobacteria. Moreover, 454-pyrosequencing revealed that the community composition of denitrifying bacteria shifted with the increase in cyanobacterial density. These results indicated that the shifts of the community composition of denitrifying bacteria might be related to cyanobacterial blooms, which could potentially lead to alterations of denitrification in eutrophic water.
A Parallel Algorithm for Large-Scale Nonconvex Penalized Quantile Regression
Creators: name: Yu, Liqun
name: Lin, Nan
name: Wang, Lan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Space Science
Molecular Biology
Biotechnology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer

description: Penalized quantile regression (PQR) provides a useful tool for analyzing high-dimensional data with heterogeneity. However, its computation is challenging due to the nonsmoothness and (sometimes) the nonconvexity of the objective function. An iterative coordinate descent algorithm (QICD) was recently proposed to solve PQR with nonconvex penalty. The QICD significantly improves the computational speed but requires a double-loop. In this article, we propose an alternative algorithm based on the alternating direction method of multiplier (ADMM). By writing the PQR into a special ADMM form, we can solve the iterations exactly without using coordinate descent. This results in a new single-loop algorithm, which we refer to as the QPADM algorithm. The QPADM demonstrates favorable performance in both computational speed and statistical accuracy, particularly when the sample size n and/or the number of features p are large. Supplementary material for this article is available online.
A Parallel Algorithm for Large-scale Nonconvex Penalized Quantile Regression
Creators: name: Yu, Liqun
name: Lin, Nan
name: Wang, Lan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Space Science
Molecular Biology
Biotechnology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer

description: Penalized quantile regression (PQR) provides a useful tool for analyzing high-dimensional data with heterogeneity. However, its computation is challenging due to the nonsmoothness and (sometimes) the nonconvexity of the objective function. An iterative coordinate descent algorithm (QICD) was recently proposed to solve PQR with nonconvex penalty. The QICD significantly improves the computational speed but requires a double-loop. In this paper, we propose an alternative algorithm based on the alternating direction method of multiplier (ADMM). By writing the PQR into a special ADMM form, we can solve the iterations exactly without using coordinate descent. This results in a new single-loop algorithm, which we refer to as the QPADM algorithm. The QPADM demonstrates favorable performance in both computational speed and statistical accuracy, particularly when the sample size n and/or the number of features p are large.
Bacillus velezensis strain HYEB5-6 as a potential biocontrol agent against anthracnose on Euonymus japonicus
Creators: name: Huang, Lin
name: Li, Qiu-Cheng
name: Hou, Yao
name: Li, Guo-Qian
name: Yang, Ji-Yun
name: Li, De-Wei
name: Ye, Jian-Ren
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Anthracnose is a foliar disease of the Euonymus shrub caused by Colletotrichum gloeosporioides. In this study, the bacterium HYEB5-6 was isolated from inside one-year-old branches of healthy Euonymus japonicus and showed significant antifungal activities against various phytopathogenic fungi, including C. gloeosporioides s.s. HYCG2-3, in dual culture experiments. The HYEB5-6 isolate significantly decreased lesion diameter and disease index caused by C. gloeosporioides inoculation on detached leaves of E. japonicus. The effects of HYEB5-6 metabolites on the invading structure of the fungus were investigated. Bacterial metabolites inhibited conidial germination, the growth of the germ tube and appressorium formation, possibly through protease and glucanase of HYEB5-6 by managing the mycelial cell wall. The HYEB5-6 isolate also produced a massive biofilm, which might facilitate leaf colonisation. These results indicate that HYEB5-6 has the potential for use as a biological control agent against C. gloeosporioides. The HYEB5-6 isolate was identified as Bacillus velezensis based on its biochemical characteristics and its 16S rRNA gene sequence.
6,7,3′,4′-Tetrahydroxyisoflavone improves the survival of whole-body-irradiated mice via restoration of hematopoietic function
Creators: name: Liu, Cong
name: Liu, Jing
name: Hao, Yuhui
name: Gu, Ying
name: Yang, Zhangyou
name: Li, Hong
name: Li, Rong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Medicine
Cell Biology
Molecular Biology
Pharmacology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Hematology

description: Purpose: 6,7,3′,4′-tetrahydroxyisoflavone (T3) is a novel chemically synthesized compound reported in our previous study. This study was designed to explore the radioprotective effect of T3, and if so, its potential mechanisms. Materials and methods: KunMing mice were exposed to various doses of γ irradiation (60 Co) after being treated with dimethyl sulfoxide (DMSO) or T3. Briefly, survival rate, dose reducing factor (DRF), body weight change (%), spleen index (SI) and thymus index (TI) of irradiated mice with or without different doses of T3 treatment were evaluated routinely. The hematopoietic function of bone marrow was emphatically investigated. In vitro experiments were performed to observe the protective effect of T3 on irradiated human lymphocyte AHH-1 cells by cell viability or flow cytometry (FCM) assays. Results: A single dose of subcutaneous administration of T3 significantly improved the survival rate, and enhanced the restoration of hematopoietic function in irradiated mice. T3 also decreased the apoptosis of irradiated AHH-1 cells in vitro. Conclusions: T3 protected mice against lethal γ irradiation-induced injury probably through the restoration of hematopoietic function. This implied that T3 could be further developed as a radioprotector.
Polydopamine/polyethyleneimine complex adhered to micrometer-sized magnetic carbon fibers for high-efficiency hemoperfusion
Creators: name: Liu, Rui-Lin
name: Wang, Yan
name: Ge, Xian-Li
name: Yu, Pei
name: Liu, Hui-Qin
name: Wang, Ming-Chan
name: Lu, Wen
name: Fu, Qiang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Carbon-based nanomaterials have recently attracted tremendous attention in adsorption, separation and biological fields. However, such modification is not always straightforward when the surface is not chemically reactive. Given this reason, most carbon materials modification processes employ reactive linkers or coupling agents, which are complicated and time-consuming. Herein, we report on a dopamine-polyethyleneimine (PEI) coating strategy to fabricate micrometer-sized magnetic carbon fiber (MSMCF)-based extracorporeal blood-cleansing sorbent for hemoperfusion. Results showed that the dopamine/PEI-coated MSMCF had a twisted fiber shape with a size range of 80–120 μm in diameter and porous structure with a specific surface area of 146 m2 g−1. Adsorption behavior of dopamine/PEI-modified MSMCF was examined by using bilirubin as a toxin model compound. Equilibrium data were well fitted to the Langmuir isotherm model with a maximal adsorption capacity of 335.1 mg g−1 at ambient temperature. The as-obtained material had relatively high bilirubin adsorption selectivity against albumin at a normal albumin concentration. In particular, the dopamine/PEI-coated MSMCF has excellent adsorption capacity and hemocompatibility compared to the MSMCF decorated only by dopamine or PEI. Therefore, this work may pave the way for enhancing the property of the extracorporeal blood-cleansing sorbent during hemoperfusion.
title: Proces doboru pracowników w przedsiębiorstwach - przegląd nowoczesnych i tradycyjnych metod aselekcji
Creators: name: Branowska, Agata
Publisher: name: Publishing House of Poznan University of Technology
Year: 2021

description: Zeszyty Naukowe Politechniki Poznańskiej. Organizacja i Zarządzanie, 83, 9-25
Different conjugated system Cd(II)/Hg(II) Schiff base complexes: syntheses, supramolecular metal−organic frameworks, luminescent properties and DFT study
Creators: name: Dong, Yu-Wei
name: Wang, Ping
name: Fan, Rui-Qing
name: Chen, Wei
name: Wang, A-Ni
name: Yang, Yu-Lin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biophysics
Biochemistry
Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: A series of different conjugated systems of 2D/3D supramolecular metal-organic frameworks (SMOFs) are constructed by C/O−H⋯Cl hydrogen bonds and π⋯π interactions. These complexes, [HgL1Cl2] (1), [HgL2Cl2] (2), [HgL3Cl2] (3), [CdL4Cl4]2 (4), and [CdL5Cl2(CH3OH)] (5), have been synthesized and characterized by single-crystal X–ray diffraction, 1H NMR, FT–IR, and EA. The X-ray diffraction analyses reveal that 1 features a 3D supramolecular framework with {44·66} topology structure, while 2, 3, and 5 exhibit 3D 6-connected {412·63} topology structures. Complex 4 shows a two-dimensional layer with 44 topology structure. Based on these varied structures caused by different conjugated system, the emission maximum wavelengths of 1–5 can be tuned in a large range of 492–587 nm. Both electron-donating ability and the conjugated system in general can support λem shift to red direction. In order to have better understanding of electronic transitions of the complexes, a time-dependent DFT study has been performed. The enhancement of the fluorescence intensities for the complexes compared to the ligands indicates potential to serve as photoactive materials.
Different conjugated system Cd(II)/Hg(II) Schiff base complexes: Syntheses, supramolecular metal−organic frameworks, luminescent properties and DFT study
Creators: name: Dong, Yu-Wei
name: Wang, Ping
name: Fan, Rui-Qing
name: Chen, Wei
name: Wang, A-Ni
name: Yang, Yu-Lin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biophysics
Biochemistry
Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: A series of different conjugated systems of 2D/3D supramolecular metal-organic frameworks (SMOFs) are constructed by C/O−H···Cl hydrogen bonds and π···π interactions. These complexes, [HgL1Cl2] (1), [HgL2Cl2] (2), [HgL3Cl2] (3), [CdL4Cl4]2 (4) and [CdL5Cl2(CH3OH)] (5), have been synthesized and characterized by single-crystal X–ray diffraction, 1H NMR, FT–IR and EA. The X-ray diffraction analyses reveal that 1 features a 3D supramolecular framework with {44·66} topology structure, while 2, 3 and 5 exhibit 3D 6-connected {412·63} topology structures. Complex 4 shows a two-dimensional layer with 44 topology structure. Based on these varied structures caused by different conjugated system, the emission maximum wavelengths of 1-5 can be tuned in a large range of 492–587 nm. Both electron-donating ability and the conjugated system in general can support λem shift to red direction. In order to have better understanding of electronic transitions of the complexes, a time-dependent DFT study has been performed. The enhancement of the fluorescence intensities for the complexes compared to the ligands indicates potential to serve as photoactive materials.
Formation of iron oxide/Pd hybrid nanostructures with enhanced peroxidase-like activity and catalytic reduction of 4-nitrophenol
Creators: name: Li, Jing
name: Cai, Junhui
name: Jia, Huimin
name: Zhang, Lixia
name: Lei, Yan
name: He, Weiwei
name: Yin, Jun-Jie
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Hematology
subject: Virology

description: Iron oxide/Pd hybrid nanostructures with controllable Pd loading from 0.05 to 1.0 (calculated as Pd/Fe molar ratio) have been synthesized by chemical reduction of Pd2+ on iron oxide particles. The combination of iron oxide and Pd exhibits enhanced peroxidase-like activity and catalytic activity toward reduction of 4-nitrophenol. The catalytic enhancements were found to be dependent on the Pd loading amount as well as the synergistic effect between iron oxide and Pd. These results suggest that iron oxide with unique surface chemical state can be an active supporter and suggest an effective way to design superior hybrid nanostructures for catalytic applications.
Formation of Iron Oxide/Pd Hybrid Nanostructures with Enhanced Peroxidase-like Activity and Catalytic Reduction of 4-Nitrophenol
Creators: name: Li, Jing
name: Cai, Junhui
name: Jia, Huimin
name: Zhang, Lixia
name: Lei, Yan
name: He, Weiwei
name: Yin, Jun-Jie
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Hematology
subject: Virology

description: Iron oxide/Pd hybrid nanostructures with controllable Pd loading from 0.05 to 1.0 (calculated as Pd/Fe molar ratio) have been synthesized by chemical reduction of Pd2+ on iron oxide particles. The combination of iron oxide and Pd exhibits enhanced peroxidase-like activity and catalytic activity toward reduction of 4-nitrophenol. The catalytic enhancements were found to be dependent on the Pd loading amount as well as the synergistic effect between iron oxide and Pd. These results suggest that iron oxide with unique surface chemical state can be an active supporter and suggest an effective way to design superior hybrid nanostructures for catalytic applications.
Terahertz investigations on photoisomerisable compounds
Creators: name: Zhang, Lei
name: Li, Jingfa
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: We performed computational terahertz studies on organometallic photoisomerisable compounds, employing both gas phase and solid phase calculations. The calculations demonstrate the potential of employing terahertz techniques on photoisomerisable compounds. In particular, the trans-ligand, counterion and crystal effects are evaluated via the density functional theory calculations. In order to fully understand the terahertz responses of the photoisomerisable compounds, their experimental terahertz spectra were obtained and compared to the calculations. The calculated spectra generally predict the experimentally observed absorption peaks, while combined gas phase and solid phase calculations offer better agreement with the experiments. The first principles calculations also reveal the sensitivity of terahertz signal on the photoisomerisation processes, suggesting a photo-terahertz set-up that could be built in the future to fast screen and fully understand the photoisomerisable compounds, for related applications such as photo-transducer and photo-switch that require photoinduced geometrical changes.