cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
NON-SYMPLECTIC AUTOMORPHISMS OF IRREDUCIBLE HOLOMORPHIC SYMPLECTIC MANIFOLDS
Creators: name: CATTANEO, ALBERTO
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: La tesi si concentra sullo studio degli automorfismi di variet� olomorfe simplettiche irriducibili di tipo K3^[n], ovvero variet� equivalenti per deformazione allo schema di Hilbert di n punti su una superficie K3, per n > 1. Negli ultimi anni, molti teoremi classici riguardanti la classificazione degli automorfismi non-simplettici di superfici K3 sono stati estesi alle variet� di tipo K3^[2]. Siamo quindi interessati a comprendere se tali risultati possono essere ulteriormente generalizzati anche al caso di variet� di tipo K3^[n], per n > 2. Nella prima parte della tesi descriviamo il gruppo degli automorfismi dello schema di Hilbert di n punti su una superficie K3 proiettiva generica, il cui reticolo di Picard � generato da un singolo fibrato ampio. Mostriamo che, se il gruppo non � triviale, esso � generato da una involuzione non-simplettica, la cui esistenza � determinata da condizioni aritmetiche che coinvolgono il numero n di punti e la polarizzazione della superficie. In aggiunta a tale caratterizzazione numerica, individuiamo anche delle condizioni necessarie e sufficienti per l'esistenza dell'involuzione riguardanti la struttura del reticolo di Picard dello schema di Hilbert. La seconda parte della tesi � dedicata allo studio degli automorfismi non-simplettici di ordine primo su variet� di tipo K3^[n]. Dopo aver investigato le propriet� del reticolo invariante dell'automorfismo e del suo complemento ortogonale all'interno del secondo reticolo di coomologia della variet�, forniamo una classificazione per le loro classi di isometria. Affrontiamo quindi il problema di individuare variet� di tipo K3^[n] dotate di automorfismi non-simplettici che inducano ognuna delle possibili azioni in coomologia presenti nella nostra classificazione. Nel caso delle involuzioni, e degli automorfismi di ordine primo dispari per n=3, 4, siamo in grado di realizzare tutti i casi ammissibili, presentando una costruzione esplicita della variet� o almeno dimostrandone l'esistenza. Tra i numerosi esempi esibiti, � di particolare rilievo un nuovo automorfismo di ordine tre su una famiglia di dimensione dieci di variet� di Lehn-Lehn-Sorger-van Straten di tipo K3^[4]. Infine, per n < 6 descriviamo le famiglie di deformazione massimali di variet� di tipo K3^[n] dotate di una involuzione non-simplettica.
Coupling between pore formation and phase separation in charged lipid membranes
Creators: name: Himeno, Hiroki
name: Ito, Hiroaki
name: Higuchi, Yuji
name: Hamada, Tsutomu
name: Shimokawa, Naofumi
name: Takagi, Masahiro
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We investigated the effect of charge on the membrane morphology of giant unilamellar vesicles (GUVs) composed of various mixtures containing charged lipids. We observed the membrane morphologies by fluorescent and confocal laser microscopy in lipid mixtures consisting of a neutral unsaturated lipid [dioleoylphosphatidylcholine (DOPC)], a neutral saturated lipid [dipalmitoylphosphatidylcholine (DPPC)], a charged unsaturated lipid [dioleoylphosphatidylglycerol (DOPG$^{\scriptsize{(-)}}$)], a charged saturated lipid [dipalmitoylphosphatidylglycerol (DPPG$^{\scriptsize{(-)}}$)], and cholesterol (Chol). In binary mixtures of neutral DOPC/DPPC and charged DOPC/DPPG$^{\scriptsize{(-)}}$, spherical vesicles were formed. On the other hand, pore formation was often observed with GUVs consisting of DOPG$^{\scriptsize{(-)}}$ and DPPC. In a DPPC/DPPG$^{\scriptsize{(-)}}$/Chol ternary mixture, pore-formed vesicles were also frequently observed. The percentage of pore-formed vesicles increased with the DPPG$^{\scriptsize{(-)}}$ concentration. Moreover, when the head group charges of charged lipids were screened by the addition of salt, pore-formed vesicles were suppressed in both the binary and ternary charged lipid mixtures. We discuss the mechanisms of pore formation in charged lipid mixtures and the relationship between phase separation and the membrane morphology. Finally, we reproduce the results seen in experimental systems by using coarse-grained molecular dynamics simulations.
description: 34 pages, 10 figures
Torsion classes, wide subcategories and localisations
Creators: name: Marks, Frederik
name: Stovicek, Jan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Representation Theory (math.RT)
subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics
subject: 16G20, 16S85, 18E40

description: For a finite dimensional algebra $A$, we establish correspondences between torsion classes and wide subcategories in $mod(A)$. In case $A$ is representation finite, we obtain an explicit bijection between these two classes of subcategories. Moreover, we translate our results to the language of ring epimorphisms and universal localisations. It turns out that universal localisations over representation finite algebras are classified by torsion classes and support $τ$-tilting modules.
description: 13 pages; version 2: new Example 4.7 based on arXiv:1610.05860, small changes in presentation, updated references
title: Guidance on Uncertainty Analysis in Exposure Assessment: Recommendation of the BfR Commissions on Exposure Estimation and Standardisation (2008 - 2017) and Evidence-based Methods in Risk Assessment (since 2018) of the German Federal Institute for Risk Assessment, 2nd edition, 12 September 2022
Creators: name: BfR Commissions On Exposure Estimation And Standardisation (2008-2017) And Evidence-Based Methods In Risk Assessment (Since 2018) Of The German Federal Institute For Risk Assessment
Publisher: name: Bundesbehörden und Einrichtungen im Geschäftsbereich des Bundesministeriums für Ernährung und Landwirtschaft (BMEL)
Year: 2022
Subjects: subject: 000

description: BfR-Stellungnahmen, vol. 2022
O «ensino das religiões» na escola - A urgência da participação cívica das religiões na auto-imagem da sociedade
Creators: name: Pinto, Paulo Mendes
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2014

description: A concessão de um espaço específico para as confissões escamoteia, esquece, o fulcro da questão: a religião não é (só) coisa das confissões. A religião enquanto actividade social é um assunto de todos os cidadãos, do todo que são as diversas partes que constituem o Estado e os seus membros, religiosos ou não.
description: Revista Lusófona de Ciência das Religiões, n. 2 (2002): Gerações, Valores e identidades religiosas | Os Media e o acontecimento religioso
An Analytical Approach to Exponent-Restricted Multiple Counting Sequences
Creators: name: Cilasun, Muhammed Hüsrev
Publisher: name: arXiv
Year: 2014
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: This study involves definitions for multiple-counting regular and summation sequences of rho. My paper introduces and proves recurrent relationships for multiple-counting sequences and shows their association with Fermat's little theorem. I also studied matrix representations and obtained generalized Binet formulas for defined sequences. As a result of multiple-counting sequence explanation, this study leads to a better understanding for distribution of composite numbers between consecutive bases.
Optimal retrofit design of multi-product batch plants
Creators: name: Vaselenak, Jane A.
name: Grossmann, Ignacio E.
name: Westerberg, Arthur W.
name: Carnegie Mellon University.Engineering Design Research Center.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: Abstract: "The problem of retrofit design of multiproduct batch plants is considered in which the optimal addition of equipment to an existing plant must be determined in view of changes in the product demands. In order to circumvent the combinatorial problem of having to analyze many alternatives the problem is formulated as a mixed-integer nonlinear program (MINLP) and solved with the outer-approximation algorithm of Duran and Grossmann. By using suitable variable transformations and approximations, the global optimum solution is guaranteed. The proposed MINLP model is also extended to the case when time-varying forecasts for product demands are given. Numerical examples are presented."
Supplementary figures and tables from Tolerant mothers: aggression does not explain solitary living in the bush Karoo rat
Creators: name: Makuya, Lindelani
name: Pillay, Neville
name: Sangweni, Siyabonga Patrick
name: Schradin, Carsten
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310901
subject: Animal behaviour

description: makuya_figues_tables_ESM.pdf
Observation of topological transition of Fermi surface from a spindle-torus to a torus in large bulk Rashba spin-split BiTeCl
Creators: name: Xiang, Fei-Xiang
name: Wang, Xiao-Lin
name: Veldhorst, Menno
name: Dou, Shi-Xue
name: Fuhrer, Michael S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The recently observed large Rashba-type spin splitting in the BiTeX (X = I, Br, Cl) bulk states due to the absence of inversion asymmetry and large charge polarity enables observation of the transition in Fermi surface topology from spindle-torus to torus with varying the carrier density. These BiTeX systems with high spin-orbit energy scales offer an ideal platform for achieving practical spintronic applications and realizing non-trivial phenomena such as topological superconductivity and Majorana fermions. Here we use Shubnikov-de Haas oscillations to investigate the electronic structure of the bulk conduction band of BiTeCl single crystals with different carrier densities. We observe the topological transition of the Fermi surface (FS) from a spindle-torus to a torus. The Landau level fan diagram reveals the expected non-trivial π Berry phase for both the inner and outer FSs. Angle-dependent oscillation measurements reveal three-dimensional FS topology when the Fermi level lies in the vicinity of the Dirac point. All the observations are consistent with large Rashba spin-orbit splitting in the bulk conduction band.
description: 28 pages, supplementary information
Herdeiros das identidades religiosas - Percursos juvenis contrastados entre as permanências e as inovações
Creators: name: Leandro, Maria Engrácia
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2014

description: No que se refere aos jovens, como noutros domínios da existência, em termos de transmissão-reelaboração das identidades, enveredam também por processos de socialização secundária, uma vez que se afiguram menos enleados por mecanismos de reprodução do idêntico e se tornam mais em sujeitos-autores do seu devir humano e espiritual. É assim no interior da família, da escola, da profissão e as identidades religiosas também não parecem escapar a este fenómeno. Nesta perspectiva,os jovens e mesmo os adultos não deixam de se re-construir em permanência.
description: Revista Lusófona de Ciência das Religiões, n. 2 (2002): Gerações, Valores e identidades religiosas | Os Media e o acontecimento religioso
title:  The Italian Way Toward E-voting
Creators: name: De Nicola  ,  Alessandro
Publisher: name: Roma TrE-Press
Year: 2023

description: Electronic voting is undoubtedly a challenge for contemporary democracies. Over the last few years, Italy has adopted a faltering approach to e-voting by fostering various and disjointed local experiments without any national strategy. Recently the Italian legislator has renewed its interest in the issue by setting up a “Fund for electronic voting” in the Ministry of the Interior Budget. The fund is aimed at encouraging e-voting experimentation addressed only to Italians residing abroad and voters who live in a different city from where they are resident. In fact, under Italian election law, the latter category of voters has to go back home to validly cast the vote. To regulate the experiments, the Ministry of the Interior adopted a decree based on the work of a commission of experts. In parallel, the Ministry of Foreign Affairs undertook its e-voting experiment for the election of the consultative body of the Committees of Italians abroad (Com.It.Es.). Starting from the above- mentioned cases, the paper aims to briefly point out some domestic constitutional issues connected to e-voting. Then, it will focus on using e-voting as a way to fill the loopholes in Italian election law according to which those voters who live far from the place of their residence are forced to go back home to validly exercise the fundamental right to vote. This factor was particularly evident during the worst phase of the Covid-19 pandemic when travel also represented a health risk for voters.
description: Roma Tre Law Review – 02/2022
Sobre a emergência da «Ciência das Religiões»
Creators: name: Pinto, Paulo Mendes
name: Almeida, Dimas De
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2014

description: Sobre a emergênciada «Ciência das Religiões»
description: Revista Lusófona de Ciência das Religiões, n. 2 (2002): Gerações, Valores e identidades religiosas | Os Media e o acontecimento religioso
Nitrogen and sulfur metabolisms encoded in prokaryotic communities associated with sea-ice algae
Creators: name: Bellas, Christopher M.
name: Campbell, Karley
name: Tranter, Martyn
name: Sánchez-Baracaldo, Patricia
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 310305
subject: Marine and estuarine ecology (incl. marine ichthyology)

description: Metagenomic Assembled Genomes from Nitrogen and sulfur metabolisms encoded in prokaryotic communities associated with sea-ice algaeBins are generated using Metabat2, bin numbers (BAT #) refer to those in Figure 2.
Multi-phase IRC Botnet and Botnet Behavior Detection Model
Creators: name: Awadi, Aymen Hasan Rashid Al
name: Belaton, Bahari
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Botnets are considered one of the most dangerous and serious security threats facing the networks and the Internet. Comparing with the other security threats, botnet members have the ability to be directed and controlled via C&C messages from the botmaster over common protocols such as IRC and HTTP, or even over covert and unknown applications. As for IRC botnets, general security instances like firewalls and IDSes do not provide by themselves a viable solution to prevent them completely. These devices could not differentiate well between the legitimate and malicious traffic of the IRC protocol. So, this paper is proposing an IDS-based and multi-phase IRC botnet and botnet behavior detection model based on C&C responses messages and malicious behaviors of the IRC bots inside the network environment. The proposed model has been evaluated on five network traffic traces from two different network environments (Virtual network and DARPA 2000 Windows NT Attack Data Set). The results show that the proposed model could detect all the infected IRC botnet member(s), state their current status of attack, filter their malicious IRC messages, pass the other normal IRC messages and detect the botnet behavior regardless of the botnet communication protocol with very low false positive rate. The proposed model has been compared with some of the existing and well-known approaches, including BotHunter, BotSniffer and Rishi regarding botnet characteristics taken in each approach. The comparison showed that the proposed model has made a progress on the comparative models by not to rely on a certain time window or specific bot signatures.
description: 10 pages, Journal paper
Optimal supply chain design and management over a multi-period horizon under demand uncertainty. Part I: MINLP and MILP models
Creators: name: Rodriguez, Maria Analia
name: Vecchietti, Aldo
name: Harjunkoski, Iiro
name: Grossmann, Ignacio E.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: An optimization model is proposed to redesign the supply chain of spare part delivery under demand uncertainty from strategic and tactical perspectives in a planning horizon consisting of multiple periods. Long term decisions involve new installations, expansions and elimination of warehouses and factories handling multiple products. It is also considered which warehouses should be used as repair work-shops in order to store, repair and deliver used units to customers. Tactical planning includes deciding inventory levels (safety stock and expected inventory) for each type of spare part in distribution centers and customer plants, as well as the connection links between the supply chain nodes. Capacity constraints are also taken into account when planning inventory levels. At the tactical level it is determined how demand of failing units is satisfied, and whether to use new or used parts. The uncertain demand is addressed by defining the optimal amount of safety stock that guarantees certain service level at a customer plant. In addition, the risk-pooling effect is taken into account when defining inventory levels in distribution centers and customer zones. Due to the nonlinear nature of the original formulation, a piece-wise linearization approach is applied to obtain a tight lower bound of the optimal solution. The formulation can be adapted to several industry-critical units and the supply chain of electric motors is provided here as an example.
An X-ray flare from 47 Cas
Creators: name: Pandey, Jeewan C
name: Karmakar, Subhajeet
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Using XMM-Newton observation, we investigate properties of a flare from the very active and poorly known stellar system 47 Cas. The luminosity at the peak of the flare was found to be 3.54x10^30 erg/s, which is ~2 times more than that at a quiescent state. The quiescent state corona of 47 Cas was represented by two temperature plasma: 3.7 and 11.0 MK. The time-resolved X-ray spectroscopy of the flare showed the variable nature of the temperature, the emission measure, and the abundance. The maximum temperature during the flare was found to be 72.8 MK. We inferred the length of a flaring loop to be 3.3x10^10 cm using a hydrodynamic loop model. Using the RGS spectra, the density during the flare was found to be 4.0x10^10 cm^-3. The loop scaling laws were also applied when deriving physical parameters of the flaring plasma.
description: AJ in press, 6 pages, 5 figures and 1 Table
FROM WIDE- TO SHORT-RANGE COMMUNICATIONS: USING HUMAN INTERACTIONS TO DESIGN NEW MOBILE SYSTEMS AND SERVICES
Creators: name: QUADRI, CHRISTIAN
Publisher: name: Universit� degli Studi di Milano
Year: 2015

description: The widespread diffusion of mobile devices has radically changed the way people interact with each other and with object of their daily life. In particular, modern mobile devices are equipped with multiple radio interfaces allowing users to interact at different spatial granularities according to the various radio technology they use. The research community is progressively moving to heterogeneous network solutions which include many different wireless technologies seamlessly integrated to address a wide variety of use cases and requirements. In 5th- Generation (5G) of mobile network we can find multiple network typology such as device-to-device (D2D), vehicular networks, machine-to-machine(M2M), and more, which are integrated in the existing mobile-broadband technology such as LTE and its future evolutions. In this complex and rich scenario, many issues and challenges are still open from a technological, architectural, and mobile services and applications points of view. In this work we provide network solutions, mobile services, and applications consistent with the 5G mobile network vision by using users interactions as a common starting point. We focus on three different spatial granularities, long, medium/short, and micro mediated by cellular network, Wi-Fi, and NFC radio technologies, respectively. We deal with various kinds of issues and challenges according to the distinct spatial granularity we consider. We start with an user centric approach based on the analysis of the characteristics and the peculiarities of each kind of interaction. Following this path, we provide contributions to support the design of new network architectures, and the development of novel mobile services and applications.
Individuelle Blueprints für summative Assessments - In fünf Schritten zur Vorlage für Prüfungsplanung und Aufgabenerstellung
Creators: name: Leimann, Jens
Publisher: name: Universität Bremen
Year: 2024
Subjects: subject: Constructive Alignment
subject: Prüfungsdidaktik
subject: Lernziele
subject: Blueprint
subject: 370

description: Ein wichtiges Instrument für die adäquate Berücksichtigung aller intendierten Lernergebnisse (Intended Learning Outcome, ILO) in Prüfungen ist ein Blueprint, also eine Blaupause mit Quoten für Aufgaben und Punktvergabe, gegliedert nach Themen und Lernzielstufen. Dieser Aufsatz macht einen Vorschlag für eine pragmatische Vorgehensweise zur Konstruktion eines Blueprints in fünf Schritten: (1) Festlegung der Themen der Lerneinheit, (2) Festlegung der ILO für jedes Thema, (3) Klassifizierung der ILO nach Lernzielniveau und Domäne (= Lernzielfeld) sowie Gewichtungsfaktor, (4) Konstruktion des Blueprints mit den Spalten Thema, ILO, Lernzielfeld und Gewichtung und (5) Ableitung der prozentualen Quoten für jedes intendierte Lernergebnis. Die Besonderheit dieses Konzeptes gegenüber bisherigen Vorschlägen zur Erstellung von Blueprints besteht darin, dass die Quoten nicht vorab und pauschal festgelegt, sondern erst im Prozess und individuell aus den fachlich klassifizierten ILO der betreffenden Lerneinheit abgeleitet werden.
Improving medication reconciliation compliance at admission in patients presenting with an acute ischaemic stroke
Creators: name: Leahy, Caoimhe
Publisher: name: Royal College of Surgeons in Ireland
Year: 2023
Subjects: classificationCode: 320905
subject: Neurology and neuromuscular diseases
classificationCode: 420319
subject: Primary health care

description: The aim of this quality improvement project is to improve compliance with medication reconciliation at the time of admission, in patients presenting with an acute ischaemic stroke. Patient harm as a result of medication errors is within the top fifteen leading causes of preventable morbidity and mortality globally. Medication reconciliation has been proposed as one of the most effective methods of reducing medication-related harm. It involves creating an up-to-date list of all the medications a patient is taking, and comparing this against their most recent prescription. Any discrepancies identified are resolved to avoid a potentially harmful event. The guidelines for best practice state that it should be completed in all patients within 24-hours of admission into a healthcare setting. Unfortunately, many organisations are struggling to achieve this. Therefore, it is recommended that priority be given to patients who are particularly vulnerable to harm, including patients with multimorbidity and polypharmacy, for example, patients presenting with an acute ischaemic stroke. Using the Lean Six Sigma framework of quality improvement and several quality improvement tools, factors affecting compliance were identified. Data analysis found that 40% of patients in this study underwent medication reconciliation within 24-hours of admission, with 81% completed by a pharmacist. This quality improvement project recommends establishing an education and training programme for staff, to increase the number of other types of healthcare professionals actively participating in the process. This would hopefully improve compliance by increasing the proportion of patients undergoing medication reconciliation within 24-hours of admission.
PROTEOMICS OF DIFFERENT CLINICAL ISOLATES OF STAPHYLOCOCCUS AUREUS
Creators: name: AHMED HUSSEIN AHMED, HANY
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: S. aureus causes severe infection even if it is mainly a harmless bacterium. It exists in a oxacillin-resistant (meticillin-resistant S. aureus, MRSA) form that represents the most important cause of antibiotic-resistant healthcare-associated infections worldwide. Most MRSA strains contain Panton-Valentine leukocidin (PVL) genes, that encode for a citotoxin that is one of the essential components of the virulence mechanisms of S. aureus. Furthermore, the presence of PVL is also associated with increased virulence of certain strains (isolates) of S. aureus. Although clinicians are currently concerned primarily with MRSA infections, methicillin-susceptible S. aureus (MSSA) infections can be present with similar epidemiologic and clinical characteristics when are PVL positive. In this study, 2-DE coupled with mass spectrometry has been used to compare protein profiles of (PVL+) and (PVL-) MRSA and MSSA S. aureus in order to highlight protein differences related to PVL presence or absence. Bacterial samples were isolated from human infections and classified on the basis of PCR analysis and antibiotic susceptibility test. Quantitative two dimensional electrophoresis was performed on MSSA and MRSA samples further classified in PVL+ and PVL-. Experiments were done in triplicate using custom IPG strips pH 4-5.5 to optimize spot resolution and to visualize different isoforms on gels. Image and statistical analysis were performed with Progenesis SameSpots software (Nonlinear Dynamics), proteins differentially expressed (ANOVA p<0.05) were identified by MALDI-TOF-TOF for identification. 2-DE image analysis revealed the differential expression of several proteins involved in iron metabolism and oxidative stress.
Um povo sacerdotal em tempo de falta de sacerdotes
Creators: name: Chittister, Joan D.
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2014

description: Que deveremos nós fazer como Povo Sacerdotal que somos?Temos que assumir responsabilidades. Temos que retomar a igreja. Temos que ensinara os dirigentes o caminho da plenitude da vida cristã!
description: Revista Lusófona de Ciência das Religiões, n. 3-4 (2003): Música e imaginários religiosos | In Memoriam o Museu de Bagdade
PARTICULATE MATTER PHAGOCYTOSIS INDUCES TISSUE FACTOR IN DIFFERENTIATING MACROPHAGES
Creators: name: MILANO, MARTA
Publisher: name: Universit� degli Studi di Milano
Year: 2016

description: Airborne exposure to particulate matter with diameter <10?m (PM10) has been linked to an increased risk of thromboembolic events, but the mechanisms are not completely understood. The aim of this study is to evaluate the effect of PM10 phagocytosis on the release of procoagulant molecules in human differentiating macrophages, and that of PM10 inhalation in an experimental model in rats. Human monocytes were separated from the peripheral blood by the lymphoprep method, differentiated in vitro, and treated with standard PM10 or vehicle. Sprague-Dawley rats were instilled intra-tracheally with PM10 or vehicle alone. The outcome was expression of proinflammatory genes and of tissue factor (TF). In human differentiating macrophages, PM10 exposure upregulated inflammatory genes, but most consistently induced TF mRNA and protein levels, but not TF protein inhibitor, resulting in increased TF membrane expression and a procoagulant phenotype. Differentiation towards the anti-inflammatory M2 phenotype inhibited PM10-mediated TF expression. TF induction required phagocytosis of PM10, whereas phagocytosis of inert particles was less effective. PM10 phagocytosis was associated with a gene expression profile consistent with intracellular retention of iron, inducing oxidative stress. Both PM10 and iron activated the stress kinases ERK1/2 pathway, involved in the induction of TF expression. In rats, alveolar exposure to PM10 was associated with pulmonary recruitment of inflammatory cells and resulted in local, but not systemic, induction of TF expression, which was sufficient to increase circulating TF levels. In conclusion, TF induction by differentiating lung macrophages, activated following phagocytosis, contributes to the increased risk of thromboembolic complications associated with PM10 exposure.
A propósito do saque do Museu de Bagdade - A negligência e o fracasso de uma ocupação americana do Iraque
Creators: name: Resende, Vasco
Publisher: name: Revista Lusófona de Ciência das Religiões
Year: 2014

description: Mas a situação desastrosa de Bagdade não é caso único. Teme-se que outras situações de pilhagem ocorram por todo o país. Todavia, como os EUA proibiram à missão da UNESCO a deslocação para fora da capital iraquiana, estamos limitados a rumores que referem que os dois museus de Babilónia foram incendiados.
description: Revista Lusófona de Ciência das Religiões, n. 3-4 (2003): Música e imaginários religiosos | In Memoriam o Museu de Bagdade
Impact of health system variability on inpatient neonatal mortality
Creators: name: Ahmad, Tahmina M.
Publisher: name: No Publisher Supplied
Year: 2023

description: Objective: To examine the association of inpatient neonatal mortality with variability in healthcare services factors such as hospital size, urban/rural designation, teaching/non-teaching status, regional location and insurance coverage.Methods: This is a pooled, cross-sectional analysis of the National Inpatient Sample (2016-2020). Information on neonatal demographics, clinical conditions, and neonatal outcomes at discharge was identified using respective ICD10-CM codes. Bivariate and multivariate analyses using logistic regression models were used to describe neonatal characteristics and to calculate the risk of mortality with each independent variable.Results: The weighted sample included 18,916,435 hospital records for infants admitted to hospital at ≤28 days of life where 99.7% were > 24 weeks Gestational Age at birth, 46.6% of them were Caucasians, and 51.4% of them were females. Neonatal death during hospitalization occurred in 42,245 cases (2.3/1,000 live birth). Infants with congenital lung malformations, chromosomal abnormalities, pulmonary hemorrhage, renal failure, abdominal wound dehiscence or seizures were 44.2, 14.5, 8.5, 8.3, 8.1, and 7.9 times more likely to suffer inpatient neonatal mortality. Compared to small-sized hospitals, medical care at medium or large size hospitals was associated with higher mortality, adjusted odds ratios (aOR)= 1.3, 95% CI:(1.1-1.3), and 1.5 (1.4-1.6), respectively. Adjusted OR for inpatient neonatal mortality in urban non-teaching or urban teaching compared to rural hospitals were 1.3 (1.1-1.3) and 2.0 (1.8-2.0), respectively. Infants in the South region had higher neonatal mortality outcomes compared to Northeast, aOR= 1.4 (1.3-1.4). Infants with public insurance coverage or no insurance coverage experienced higher inpatient neonatal mortality compared to those with private insurance, aOR= 1.4 (1.2-1.4) and 2.3 (2.1-2.3), respectively. Conclusion: Factors related to variability in healthcare delivery may play a role in inpatient neonatal mortality. A qualitative analysis is needed to explore how these factors relate to increased neonatal mortality in certain hospital settings.
Local field topology behind light localization and metamaterial topological transitions
Creators: name: Tong, Jonathan
name: Mercedes, Alvin
name: Chen, Gang
name: Boriskina, Svetlana V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We revisit the mechanisms governing the sub-wavelength spatial localization of light in surface plasmon polariton (SPP) modes by investigating both local and global features in optical powerflow at SPP frequencies. Close inspection of the instantaneous Poynting vector reveals formation of optical vortices - localized areas of cyclic powerflow - at the metal-dielectric interface. As a result, optical energy circulates through a subwavelength-thick 'conveyor belt' between the metal and dielectric where it creates a high density of optical states (DOS), tight optical energy localization, and low group velocity associated with SPP waves. The formation of bonding and anti-bonding SPP modes in metal-dielectric-metal waveguides can also be conveniently explained in terms of different spatial arrangements of localized powerflow vortices between two metal interfaces. Finally, we investigate the underlying mechanisms of global topological transitions in metamaterials composed of multiple metal and dielectric films, i.e., transitions of their iso-frequency surfaces from ellipsoids to hyperboloids, which are not accompanied by the breaking of lattice symmetry. Our analysis reveals that such global topological transitions are governed by the dynamic local re-arrangement of local topological features of the optical interference field, such as vortices and saddle points, which reconfigures global optical powerflow within the metamaterial. These new insights into plasmonic light localization and DOS manipulation not only help to explain the well-known properties of SPP waves but also provide useful guidelines for the design of plasmonic components and materials for a variety of practical applications.
description: 25 pages, 9 figures, Ch. 8 of Singular and Chiral Nanoplasmonics (S.V. Boriskina and N.I. Zheludev Eds.) Pan Stanford, Singapore, 2014
Supplementary materials from Does trappability and self-selection influence cognitive performance?
Creators: name: Ashton, Benjamin J.
name: Thornton, Alex
name: Speechley, Elizabeth M.
name: Ridley, Amanda R.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour

description: Recent research has highlighted how trappability and self-selection—the processes by which individuals with particular traits may be more likely to be caught or to participate in experiments—may be sources of bias in studies of animal behaviour and cognition. It is crucial to determine whether such biases exist, and if they do, what effect they have on results. In this study, we investigated if trappability (quantified through ‘ringing status’—whether or not a bird had been trapped for ringing) and self-selection are sources of bias in a series of associative learning experiments spanning 5 years in the Western Australian magpie (Gymnorhina tibicen dorsalis). We found no evidence of self-selection, with no biases in task participation associated with sex, age, group size or ringing status. In addition, we found that there was no effect of trappability on cognitive performance. These findings give us confidence in the results generated in the animal cognition literature and add to a growing body of literature seeking to determine potential sources of bias in studies of animal behaviour, and how they influence the generalizability and reproducibility of findings.
Constitution, Laws and Rules of Order for the Government of Subordinate Divisions of the Sons of Temperance Including By-Laws of Division, No. Located at. Revised Edition.
Creators: name: Alcohol Research Documentation, Inc.
Publisher: name: The National Division of North America [National Division, Sons of Temperance of North America]
Year: 1897

description: Copy of the laws and rules of divisions of the Sons of Temperance of North America, including by-laws for an unidentified chapter of the organization.
Numerical simulations of acoustically generated gravitational waves at a first order phase transition
Creators: name: Hindmarsh, Mark
name: Huber, Stephan J.
name: Rummukainen, Kari
name: Weir, David J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present details of numerical simulations of the gravitational radiation produced by a first order thermal phase transition in the early universe. We confirm that the dominant source of gravitational waves is sound waves generated by the expanding bubbles of the low-temperature phase. We demonstrate that the sound waves have a power spectrum with a power-law form between the scales set by the average bubble separation (which sets the length scale of the fluid flow $L_\text{f}$) and the bubble wall width. The sound waves generate gravitational waves whose power spectrum also has a power-law form, at a rate proportional to $L_\text{f}$ and the square of the fluid kinetic energy density. We identify a dimensionless parameter $\tildeΩ_\text{GW}$ characterising the efficiency of this "acoustic" gravitational wave production whose value is $8π\tildeΩ_\text{GW} \simeq 0.8 \pm 0.1$ across all our simulations. We compare the acoustic gravitational waves with the standard prediction from the envelope approximation. Not only is the power spectrum steeper (apart from an initial transient) but the gravitational wave energy density is generically larger by the ratio of the Hubble time to the phase transition duration, which can be 2 orders of magnitude or more in a typical first order electroweak phase transition.
description: 22 pages, 13 figures; v2: typos in section IIIE (Source lifetime) corrected, new appendix on GW production in an expanding universe, other minor corrections, version accepted for publication
Brouillard - Kundschaft in Schwarzwaldgemeinden
Creators: name: Perrollaz, Cartier & Co
Publisher: name: [s.n.]
Year: 1777

description: Darin: Lose Einlage in eingeklebter Tasche ganz hinten
description: Die frühesten Übertragungsvermerke beziehen sich auf das Jahr 1776; Seiten 4-5, 8-10, 12-14, 16-20, 22-28, 31, 33, 41-46, 50-124 sind leer
description: Französisch
description: Verzeichnung=Description=Inventaire 2014 ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Sebastian Preher
One smoothing property of the scattering map of the KdV on $\mathbb R$
Creators: name: Maspero, Alberto
name: Schaad, Beat
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35Q53 (Primary) 35P25, 37K15 (Secondary)

description: In this paper we prove that in appropriate weighted Sobolev spaces, in the case of no bound states, the scattering map of the Korteweg-de Vries (KdV) on $\mathbb R$ is a perturbation of the Fourier transform by a regularizing operator. As an application of this result, we show that the difference of the KdV flow and the corresponding Airy flow is 1-smoothing.
RNA IN DNA: FROM STRUCTURE TO GENOME INSTABILITY
Creators: name: MERONI, ALICE
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: The presence of RNA in the genome of living cells is one of the emerging topics of the last two decades and has been implicated in many biological processes. I focused my attention on ribonucleotides (rNMPs) embedded into DNA during genome duplication, as a threat to its integrity. In fact, rNMPs have been classified as the most frequent non-canonical nucleotides introduced during genome duplication by DNA polymerases. Such high incorporation frequency has been related to a physiological role in mismatch repair, but it can be easily turned into a source of genomic instability if rNMPs are not removed from DNA. This task is performed by RNase H activities that enable error-free repair of embedded single and multiple ribonucleotides. I first approached the issue of ribonucleotides incorporation into DNA from a physical point of view. Utilizing Atomic Force Microscopy I studied how ribonucleotides intrusions impact on DNA structure. The results obtained provided new insights on the structural changes imposed by ribonucleotides persistence into DNA. The other part of my Ph.D. project concerned the study of rNMPs incorporation in vivo, using the budding yeast S. cerevisiae as a model organism. The second aim was to unravel the function of the Translesion Synthesis polymerase ? (Pol ?) when the genome contains residual ribonucleotides and when deoxyribonucleotides (dNTPs) pools are depleted. We found that DNA polymerase ? is responsible for the cell lethality observed when dNTPs are scarce and RNase H activities are defective. Therefore, I explored and characterized this unexpected toxic activity. We propose a model where Pol ? supports cell survival in low dNTPs conditions by promoting DNA replication using ribonucleotides. While this activity is normally beneficial to wild type cells, it is highly toxic to cells defective for RNase H activities.
Collinear, two-color optical Kerr effect shutter for ultrafast time-resolved imaging
Creators: name: Purwar, Harsh
name: Idlahcen, Saïd
name: Rozé, Claude
name: Sedarsky, David
name: Blaisot, Jean-Bernard
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Imaging with ultrashort exposure times is generally achieved with a crossed-beam geometry. In the usual arrangement, an off-axis gating pulse induces birefringence in a medium exhibiting a strong Kerr response (commonly carbon disulfide) which is followed by a polarizer aligned to fully attenuate the on-axis imaging beam. By properly timing the gate pulse, imaging light experiences a polarization change allowing time-dependent transmission through the polarizer to form an ultrashort image. The crossed-beam system is effective in generating short gate times, however, signal transmission through the system is complicated by the crossing angle of the gate and imaging beams. This work presents a robust ultrafast time-gated imaging scheme based on a combination of type-I frequency doubling and a collinear optical arrangement in carbon disulfide. We discuss spatial effects arising from crossed-beam Kerr gating, and examine the imaging spatial resolution and transmission timing affected by collinear activation of the Kerr medium, which eliminates crossing angle spatial effects and produces gate times on the order of 1 ps. In addition, the collinear, two-color system is applied to image structure in an optical fiber and a gasoline fuel spray, in order to demonstrate image formation utilizing ballistic or refracted light, selected on the basis of its transmission time.
description: 13 pages, 10 figures
NORMAN Data Collection materials
Creators: name: Francis, Kathryn
name: Granger, Josh
name: Branney, Peter
name: Blount, Joe
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: quality of life
subject: e-counselling
subject: penile cancer
subject: counselling
subject: patients experiences
subject: male cancers
subject: tele-health
subject: testicular cancer
subject: urology

description: Materials for data collection, which was administered using the Gorilla online experimental platform.
Brief an Jacob Zwinger
Creators: name: Eggs, Johann Friedrich
Publisher: name: [s.n.]
Year: 1607

description: von Johann Friedrich Eggs
description: Abschrift: UB Basel Handschriften G2 II 14:fol.169
description: Lateinisch
description: Deutsch
description: Verzeichnung=Description=Inventaire Oktober 2010 Vollständige Rekatalogisierung nach Standortverzeichnis Frey-Gryn Mscr II 1/III 18
description: Digitalisierung=Digitization=Numérisation Juli 2022 TIFF
Optimality-based bound contraction with multiparametric disaggregation for the global optimization of mixed-integer bilinear problems
Creators: name: Castro, Pedro M.
name: Grossmann, Ignacio E.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: We address nonconvex mixed-integer bilinear problems where the main challenge is the computation of a tight upper bound for the objective function to be maximized. This can be obtained by using the recently developed concept of multiparametric disaggregation following the solution of a mixed-integer linear relaxation of the bilinear problem. Besides showing that it can provide tighter bounds than a commercial global optimization solver within a given computational time, we propose to also take advantage of the relaxed formulation for contracting the variables domain and further reduce the optimality gap. Through the solution of a real-life case study from a hydroelectric power system, we show that this can be an efficient approach depending on the problem size. The relaxed formulation from multiparametric formulation is provided for a generic numeric representation system featuring a base between 2 (binary) and 10 (decimal).
Brief an [Jacob] Zwinger
Creators: name: Eggs, Johann Friedrich
Publisher: name: [s.n.]
Year: 1610

description: von Johan[n] Friedrich Eggs
description: Lateinisch
description: Deutsch
description: Verzeichnung=Description=Inventaire Oktober 2010 Vollständige Rekatalogisierung nach Standortverzeichnis Frey-Gryn Mscr II 1/III 18
description: Digitalisierung=Digitization=Numérisation Juli 2022 TIFF
MOLECULAR DYNAMICS SIMULATIONS OF BIOLOGICAL MACROMOLECULES: APPLICATIONS TO STRUCTURAL VACCINOLOGY AND PEPTIDE DESIGN
Creators: name: SCARABELLI, GUIDO
Publisher: name: Universit� degli Studi di Milano
Year: 2010

description: This thesis work is splitted into two parts. The first one is about a computational method for epitope predictions on antigenic proteins, while the second one is related to the characterization of folding/unfolding processes of small natural polypeptides. Starting with the first topic, an increasing number of functional studies of proteins have shown that sequence and structural similarities alone may not be sufficient for reliable prediction of their interaction properties. This is particularly true for proteins recognizing specific antibodies, where the prediction of antibody-binding sites, called epitopes, has proven challenging. The antibody-binding properties of an antigen depend on its structure and related dynamics. Aiming to predict the antibody-binding regions of a protein, we investigate a new approach based on the integrated analysis of the dynamical and energetic properties of antigens, to identify nonoptimized, low-intensity energetic interaction networks in the protein structure isolated in solution. The method is based on the idea that recognition sites may correspond to localized regions with low-intensity energetic couplings with the rest of the protein, which allows them to undergo conformational changes, to be recognized by a binding partner, and to tolerate mutations with minimal energetic expense. Upon analyzing the results on isolated proteins and benchmarking against antibody complexes, it is found that the method successfully identifies binding sites located on the protein surface that are accessible to putative binding partners. The combination of dynamics and energetics can thus discriminate between epitopes and other substructures based only on physical properties. A public web server (BEPPE) has been implemented with MLCE method in order to make it available to the scientific community. Changing topic to folding/unfolding, the analysis of the folding mechanism in peptides adopting well defined secondary structure is fundamental to understand protein folding. Herein, we describe the thermal unfolding of two 15-mer polypeptides (called QK and QK-L10A) homologue to the vascular endothelial growth factor binding region. In particular, on the basis of the temperature dependencies, we characterize the molecules through the combination of spectroscopic (CD and NMR) and computational analyses (MD) highlighting their folding/unfolding steps and how these structures can be used in peptide design.