cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2 of Valsartan in combination with metformin and gliclazide in diabetic rat model using developed RP-HPLC method
Creators: name: Patra, Rasmita
name: Kollati, Yedukondalu
name: NS, Sampath Kumar
name: Dirisala, Vijaya R.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 2: Supplementary Fig. 2. Valsartan effect on diabetic rats in presence of metformin. Mean plasma concentrations (n = 6, μg.ml−1).
title: MAPK Signaling Pathway: A Key Player in Rheumatoid Arthritis Pathogenesis
title: MAPK Vs Rheumatoid Arthritis
titleType: Subtitle
Creators: name: Moshin, Fatima
name: Ali, Khubaib
name: Khaliq, Hafiz Muhammad Haseeb
Publisher: name: Zenodo openAIRE, Google Scholar Indexed
Year: 2024
Subjects: MAPK , Joints disease Management, Rheumatoid Arthritis, Pathophysiology, cell signaling

description: ABSTRACT

Chronic inflammation in RA is caused by abnormal regulation of a communication network within cells. This network consists of extracellular stimuli including chemokines, cytokines, and matrix-degrading enzymes which influence the cells to participate in inflammatory processes. These mediators released in the extracellular matrix bind to receptors on the plasma membrane and activate or inactivate intracellular transcription pathways. This paper demonstrated the role of the MAPK cascade in inflammatory signal transduction pathways. It is significant for the maintenance, regulation, and induction of chronic inflammation in RA, and therefore its components can act as potential molecular targets for MAPK inhibitors to control and inhibit inflammation. There is evidence of specific activation of the p38 MAPK pathway in inflammatory arthritis and joint diseases. Here we describe the regulation, function, and activation of MAPK specifically p38 MAPK as well as the role of this pathway in the disease.

Keywords: MAPK , Joints disease Management, Rheumatoid Arthritis, Pathophysiology, cell signaling

 

INTRODUCTION

Rheumatoid arthritis is a multifaceted autoimmune disorder characterized by pain and swelling of joints synovial inflammation, and cartilage destruction. It doesn’t only cause joint irregularities but various other symptoms including anemia, fever, muscle weaknesses, and osteoporosis that can dysregulate functions of the nervous, urinary, and cardiovascular systems. Generally, it is believed that genetic and environmental factors are involved in causing RA because the exact cause remains unknown. There is an involvement of joints being mistakenly attacked by the immune system causing joint capsule thickening of synovial fluid and inflammation and causing damage to cartilage and bones at specific sites. (1). During later stages of the disease, intense degrees of deformity and rigidity of joints are observed, causing skeletal muscle atrophy, bone corrosion, and damage of tendons and ligaments. RA impacts other extra-articular organs and tissues including nerves, kidneys, eyes, skin, lungs, bones, heart, and liver. (2)  The development and promotion of rheumatoid arthritis are caused by abnormal signaling pathways of various cytokines. Joints which are local inflammatory sites in RA, abnormality in signaling transduction pathways can lead to the release of pro-inflammatory mediators in excessive amounts which leads to the proliferation of fibroblast-like synoviocytes (FLS) (3). Different signaling pathways involved in RA pathology include MAPK (mitogen-activated protein kinase pathway), Nf-Kb, P13K pathway, and JAK/STAT signaling cascade.
Summary of experimental studies at CERN on a positron source using crystal effects
Creators: name: Artru, X.
name: Baier, V.
name: Beloborodov, K.
name: Bogdanov, A.
name: Bukin, A.
name: Burdin, S.
name: Chehab, R.
name: Chevallier, M.
name: Cizeron, R.
name: Dauvergne, D.
name: Dimova, T.
name: Druzhinin, V.
name: Dubrovin, M.
name: Gatignon, L.
name: Goluev, V.
name: Jejcic, A.
name: Keppker, P.
name: Kirsch, R.
name: Kulibaba, V.
name: Lautesse, P.
name: Major, J.
name: Poizat, J. -C.
name: Potylitsin, A.
name: Remillieux, J.
name: Serednyakov, S.
name: Shary, V.
name: Strakhovenko, V.
name: Sylvia, C.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: New kind of positron sources for future linear colliders, where the converter is a tungsten crystal oriented on the <111> axis, has been studied at CERN in the WA103 experiment. In such sources the photons which create the $e^+ e^-$ pairs result from channeling radiation and coherent bremsstrahlung. In this experiment electron beams of 6 and 10 GeV were sent on different kinds of targets: a 4 mm thick crystal, a 8 mm thick crystal and a compound taraget (4 mm crystal + 4 mm amorphous disk). An amorphous tungsten target 20 mm thick was also used for comparison with the 8 mm crystal. Tracks of outgoing charged particles were detected and analyzed by a drift chamber in a magnetic field. The energy and angle spectra of the positrons were obtained for energies up to 150 MeV and angles up to 30 degrees. The measured positron distribution in momentum space (longitudinal versus transverse) is also presented, giving a full momentum space description of the source. Results on outgoing photons are also presented. A significant enhancement of both photon and positron production is clearly observed. At 10 GeV incident energy, the positron enhancement factor is 4 for the 4 mm crystal, about 2 for the 8 mm crystal. Besides, the simulation code for the crystal processes is validated by a quite good agreement between the simulated and experimental spectra, both for positrons and photons.
title: MAPK Signaling Pathway: A Key Player in Rheumatoid Arthritis Pathogenesis
title: MAPK Vs Rheumatoid Arthritis
titleType: Subtitle
Creators: name: Moshin, Fatima
name: Ali, Khubaib
name: Khaliq, Hafiz Muhammad Haseeb
Publisher: name: Zenodo openAIRE, Google Scholar Indexed
Year: 2022
Subjects: MAPK , Joints disease Management, Rheumatoid Arthritis, Pathophysiology, cell signaling

description: ABSTRACT

Chronic inflammation in RA is caused by abnormal regulation of a communication network within cells. This network consists of extracellular stimuli including chemokines, cytokines, and matrix-degrading enzymes which influence the cells to participate in inflammatory processes. These mediators released in the extracellular matrix bind to receptors on the plasma membrane and activate or inactivate intracellular transcription pathways. This paper demonstrated the role of the MAPK cascade in inflammatory signal transduction pathways. It is significant for the maintenance, regulation, and induction of chronic inflammation in RA, and therefore its components can act as potential molecular targets for MAPK inhibitors to control and inhibit inflammation. There is evidence of specific activation of the p38 MAPK pathway in inflammatory arthritis and joint diseases. Here we describe the regulation, function, and activation of MAPK specifically p38 MAPK as well as the role of this pathway in the disease.

Keywords: MAPK , Joints disease Management, Rheumatoid Arthritis, Pathophysiology, cell signaling

 

INTRODUCTION

Rheumatoid arthritis is a multifaceted autoimmune disorder characterized by pain and swelling of joints synovial inflammation, and cartilage destruction. It doesn’t only cause joint irregularities but various other symptoms including anemia, fever, muscle weaknesses, and osteoporosis that can dysregulate functions of the nervous, urinary, and cardiovascular systems. Generally, it is believed that genetic and environmental factors are involved in causing RA because the exact cause remains unknown. There is an involvement of joints being mistakenly attacked by the immune system causing joint capsule thickening of synovial fluid and inflammation and causing damage to cartilage and bones at specific sites. (1). During later stages of the disease, intense degrees of deformity and rigidity of joints are observed, causing skeletal muscle atrophy, bone corrosion, and damage of tendons and ligaments. RA impacts other extra-articular organs and tissues including nerves, kidneys, eyes, skin, lungs, bones, heart, and liver. (2)  The development and promotion of rheumatoid arthritis are caused by abnormal signaling pathways of various cytokines. Joints which are local inflammatory sites in RA, abnormality in signaling transduction pathways can lead to the release of pro-inflammatory mediators in excessive amounts which leads to the proliferation of fibroblast-like synoviocytes (FLS) (3). Different signaling pathways involved in RA pathology include MAPK (mitogen-activated protein kinase pathway), Nf-Kb, P13K pathway, and JAK/STAT signaling cascade.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Cart. 193 (11 H 78), f. 0229v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Archives départementales de la Côte-d'Or, Cart. 193 (11 H 78), f. 0229v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Archives départementales de la Côte-d'Or, Cart. 193 (11 H 78), f. 0229v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: abbaye de Cîteaux
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: http://www.wikidata.org/entity/Q843261
59Co-NMR Probe for Stepwise Magnetization and Magnetotransport in SrCo6O11 with Metallic Kagome Layer and Triangular Lattice with Local Moments
Creators: name: Mukuda, Hidekazu
name: Kitaoka, Yoshio
name: Ishiwata, Shintaro
name: Saito, Takashi
name: Shimakawa, Yuichi
name: Harima, Hisatomo
name: Takano, Mikio
Publisher: name: arXiv
Year: 2006
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report on novel magnetic and electronic properties of SrCo6O11 that exhibits a unique stepwise magnetization and its relevant magnetotransport phenomena investigated by the site-selective 59Co nuclear magnetic resonance (NMR) at zero and applied magnetic fields. This compound is composed of three Co sites in the unit cell, i.e., Co(1) in the metallic Kagome layer, a Co(2) dimerized pillar between the layers and Co(3) in the triangular lattice. Zero-field NMR spectra have revealed that large local moments at the Co(3) sites are magnetically ordered without any trace of bulk magnetization M at zero field. The field-swept NMR spectra show that the internal hyperfine field at the Co(1) site is derived from fully polarized moments Ms at the Co(3) sites in the "1"-plateau state at fields higher than 2.5 T, whereas it is partially cancelled out in the "1/3"-plateau state in which one-third of Ms is induced at intermediate fields once a small field is applied. It has been clarified from a microscopic point of view that the local moments at Co(3) site undergo a field-induced ferrimagnetic (up-up-down)-to-ferromagnetic (up-up-up) transition, which is consistent with the evidence obtained from the recent neutron diffraction experiment. The Co(1) Kagome layer and the dimerized pillar Co(2) site between the layers are of nonmagnetic origin, suggesting that the nearly quasi-2D metallic conductivity is dominated by nonmagnetic Co(1) and Co(2) sites. Consequently, unique magneto-transport phenomena observed in SrCo6O11 are demonstrated owing to the interaction between the conduction electrons at the Co(1) and Co(2) sites and the local moments at Co(3) sites.
description: 6 pages, 6 figures. To be published in J.Phys.Soc.Jpn, Vol.75, No.9 (2006)
Association Between Depression and HIV Care Engagement Outcomes Among Patients Newly Initiating ART in Lilongwe, Malawi
Creators: name: Pence, B.W.
name: Pettifor, A.E.
name: Gaynes, B.N.
name: Hosseinipour, M.C.
name: Stockton, M.A.
name: Maselko, J.
name: Udedi, M.
name: Mphonda, S.M.
name: Kulisewa, K.
Publisher: name: Springer
Year: 2021

description: As in other sub-Saharan countries, the burden of depression is high among people living with HIV in Malawi. However, the association between depression at ART initiation and two critical outcomes—retention in HIV care and viral suppression—is not well understood. Prior to the launch of an integrated depression treatment program, adult patients were screened for depression at ART initiation at two clinics in Lilongwe, Malawi. We compared retention in HIV care and viral suppression at 6 months between patients with and without depression at ART initiation using tabular comparison and regression models. The prevalence of depression among this population of adults newly initiating ART was 27%. Those with depression had similar HIV care outcomes at 6 months to those without depression. Retention metrics were generally poor for those with and without depression. However, among those completing viral load testing, nearly all achieved viral suppression. Depression at ART initiation was not associated with either retention or viral suppression. Further investigation of the relationship between depression and HIV is needed to understand the ways depression impacts the different aspects of HIV care engagement.
Dissipation of the String Embedding Dimension in the Singlet Sector of a Matrix Model at Large $α^\prime$
Creators: name: Feinberg, Joshua
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The one dimensional Fermi gas of matrix eigenvalues of the Marinari-Parisi model at positive values of the cosmological constant is generalised.The number of matrix eigenvalues (i.e. gas particles) is varied while keeping the effective potential fixed. This model exhibits a transition from a phase whose continuum behaviour is that of $c=1$ conformal matter coupled to gravity to the well known pure gravity phase of the original model.The former phase is character- ised by an extremely large Regge slope $α^\prime$ which scales as $β^{2/5}$ causing the scaling regions of the two phases to overlap. In this way a continuous flow from one phase to the other is made poss- ible. This phase transition occurs in the singlet sector of the matrix model. The density of states and the two puncture correlator at non zero momenta are calculated on the sphere and are found to behave very differ- ently in the two phases,a fact which demonstrates the phase transition. We comment on a possible relation between this transition and large α^\prime$ semiclassical expansions in the continuum.
description: (PHR74JF@Technion.bitnet),TECHNION-PH-93-13,33 pages
Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach
Creators: name: Sripaipan, T.
name: Levintow, S.N.
name: Pence, B.W.
name: Go, V.F.
name: Quan, V.M.
name: Latkin, C.A.
name: Ha, T.V.
name: Chu, V.A.
name: Powers, K.A.
Publisher: name: Springer
Year: 2021

description: The burden of depression and HIV is high among people who inject drugs (PWID), yet the effect of depression on transmission risk behaviors is not well understood in this population. Using causal inference methods, we analyzed data from 455 PWID living with HIV in Vietnam 2009–2013. Study visits every 6 months over 2 years measured depressive symptoms in the past week and injecting and sexual behaviors in the prior 3 months. Severe depressive symptoms (vs. mild/no symptoms) increased injection equipment sharing (risk difference [RD] = 3.9 percentage points, 95% CI −1.7, 9.6) but not condomless sex (RD = −1.8, 95% CI −6.4, 2.8) as reported 6 months later. The cross-sectional association with injection equipment sharing at the same visit (RD = 6.2, 95% CI 1.4, 11.0) was stronger than the longitudinal effect. Interventions on depression among PWID may decrease sharing of injection equipment and the corresponding risk of HIV transmission. Clinical trial registration ClinicalTrials.gov NCT01689545.
Additional file 1: of Impediments to communication and relationships between infertility care providers and patients
Creators: name: Klitzman, Robert
Publisher: name: figshare
Year: 2018
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Semi-Structured Interview Questionnaire (Sample Questions). (DOCX 15 kb)
Validation of screening tools for common mental health disorders in the methadone maintenance population in Hanoi, Vietnam
Creators: name: Go, V.
name: Gaynes, B.N.
name: Ha, T.V.
name: Stockton, M.A.
name: Mughal, A.Y.
name: Pence, B.W.
name: Bui, Q.
Publisher: name: BioMed Central Ltd
Year: 2021

description: Background: Common mental health disorders (CMDs), including depression, anxiety and post-traumatic stress disorder (PTSD) may worsen both HIV and drug use outcomes, yet feasible tools to accurately identify CMDs have received limited study in this population. We aimed to validate the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder screen (GAD-7) and Primary Care PTSD screen for DSM-5 (PC-PTSD-5) in a methadone maintenance therapy (MMT) patient population in Hanoi, Vietnam. Methods: We conducted a cross-sectional survey. The PHQ-9, GAD-7, and PC-PTSD-5 were administered to MMT patients. A blinded interviewer administered the Mini-International Neuropsychiatric Interview (MINI) as the reference gold standard. Total scores of each tool were compared with the MINI diagnoses using a receiver operating characteristic curves, and we identified the optimal respective cut-off scores using the Youden’s Index. Results: We enrolled 400 MMT patients. Approximately 99.3% were male (n = 397) and 21.8% (n = 87) were HIV positive. The prevalence of major depressive disorder, generalized anxiety disorder and PTSD, respectively, was 10.5, 4 and 2%. Optimal cut-off scores for the PHQ-9, GAD-7 and PC-PTSD were ≥ 5, ≥3, and ≥ 4 with a sensitivity/specificity of 95.2%/91.9, 93.8%/87.5, and 62.5%/95.2%. Conclusions: The prevalence of CMDs in the MMT population was lower than expected. A lower cut-off score may be considered when screening for CMDs in this population. Further research should investigate the validity of somatic symptom-based screening tools among other drug-using or MMT populations.
Novel approaches to spectral properties of correlated electron materials: From generalized Kohn-Sham theory to screened exchange dynamical mean field theory
Creators: name: Delange, Pascal
name: Backes, Steffen
name: van Roekeghem, Ambroise
name: Pourovskii, Leonid
name: Jiang, Hong
name: Biermann, Silke
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The most intriguing properties of emergent materials are typically consequences of highly correlated quantum states of their electronic degrees of freedom. Describing those materials from first principles remains a challenge for modern condensed matter theory. Here, we review, apply and discuss novel approaches to spectral properties of correlated electron materials, assessing current day predictive capabilities of electronic structure calculations. In particular, we focus on the recent Screened Exchange Dynamical Mean-Field Theory scheme and its relation to generalized Kohn-Sham theory. These concepts are illustrated on the transition metal pnictide BaCo$_2$As$_2$ and elemental zinc and cadmium.
description: Accepted for publication in the Journal of the Physical Society of Japan
Correlates of self-reported history of mental health help-seeking: a cross-sectional study among individuals with symptoms of a mental or substance use disorder initiating care for HIV in Cameroon
Creators: name: Ebasone, P.V.
name: Ajeh, R.
name: Parcesepe, A.M
name: Nash, D.
name: Anastos, K.
name: Nsame, D
name: Wainberg, M.
name: Yotebieng, M.
name: Pefura-Yone, E
name: Filiatreau, L.M.
name: Dzudie, A.
name: Pence, B.
Publisher: name: BioMed Central Ltd
Year: 2021

description: Background: Mental health and substance use disorders (MSDs) increase the risk of poor human immunodeficiency virus (HIV) care outcomes among people living with HIV (PLWH). Receipt of mental health care may improve these adverse outcomes. We aimed to identify correlates of prior mental health help-seeking among PLWH with symptoms of an MSD in Cameroon. Methods: We characterize prior mental health help-seeking from formal (mental health specialist/general medical provider) and informal (traditional healer/religious leader) sources among 161 people with symptoms of depression (Patient Health Questionnaire-9 scores> 9), anxiety (General Anxiety Disorder-7 scores> 9), probable post-traumatic stress disorder (PTSD Checklist for DSM-5 scores> 30), or possible alcohol use disorder (Alcohol Use Disorders Identification Test scores≥16) who were newly entering HIV care at three healthcare facilities in Cameroon between June 2019 and March 2020. Help-seeking was defined as ever speaking to a formal or informal source about emotional problems, sadness, or the way they were feeling or behaving. We estimated the association between sociodemographic and psychosocial measures and lifetime mental health help-seeking from each type of source using log-binomial regression. Results: Overall, 55.3% of 161 PLWH with MSD symptoms reported prior mental health help-seeking, with 24.2% and 46.0% seeking help from formal and informal sources, respectively. Religious leaders were the most common source of help (40.4%), followed by general medical professionals (22.4%), traditional healers (16.8%), and mental health specialists (7.4%). Individuals with higher depressive, anxiety, and trauma symptom severity scores were more likely to have sought help than those with lower scores. Individuals with possible alcohol use disorder were the least likely to have sought help. Prior help-seeking was more common among those reporting a higher number of lifetime traumatic events (prevalence ratio [PR]: 1.06; 95% confidence interval [CI]: 1.01, 1.11) and those with a history of emotional intimate partner violence (PR: 1.34; 95% CI: 1.01, 1.80). Conclusions: Prior mental health help-seeking was associated with psychosocial stressors. Help-seeking from informal networks was more common than formal help-seeking. Training in the provision of evidence-based mental health support for informal networks could improve access to mental health care for PLWH with MSDs in Cameroon.
Discovery of nearly coherent oscillations with a frequency of ~567 Hz during type-I X-ray bursts of the X-ray transient and eclipsing binary X 1658-298
Creators: name: Wijnands, Rudy
name: Strohmayer, Tod
name: Franco, Lucia M.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the discovery of nearly coherent oscillations with a frequency of 567 Hz during type-I X-ray bursts from the X-ray transient and eclipsing binary X 1658-298. If these oscillations are directly related to the neutron star rotation then the spin period of the neutron star in X 1658-298 is 1.8 ms. The oscillations can be present during the rise or decay phase of the bursts. Oscillations during the decay phase of the bursts show an increase in the frequency of 0.5 to 1 Hz. However, in one particular burst the oscillations reappear at the end of the decay phase at about 571.5 Hz. This represents an increase in oscillation frequency of about 5 Hz which is the largest frequency change seen so far in a burst oscillation. It is unclear if such a large change can be accommodated by present models used to explain the frequency evolution of the oscillations. The oscillations at 571.5 Hz are unusually soft compared to the oscillations found at 567 Hz. We also observed several bursts during which the oscillations are detected at much lower significance or not at all. Most of these bursts happen during periods of X-ray dipping behavior, suggesting that the X-ray dipping might decrease the amplitude of the oscillations (although several complications exist with this simple picture). We discuss our discovery in the framework of the neutron star spin interpretation.
description: Accepted for publication in ApJ Letters (21 December 2000). Addition of a table containing the burst properties
Best practice in government and institutional policy to increase female participation in STEM
Creators: name: Scott, T.
Publisher: name: Zenodo
Year: 2019
Subjects: Women, Science, CBHE, EU, gender, STEM, W-STEM, benchmarking, good practice

description: Best practice in government and institutional policy to increase female participation in STEM presented into the First Benchmarking Round session within the 2nd face-to-face meeting of the W-STEM ERASMUS + Capacity-building in Higher Education European Project (Ref. 598923-EPP-1-2018-1-ES-EPPKA2-CBHE-JP), which was held in Universidad del Norte, Barranquilla (Colombia), 27-29 November 2019.
description: W-STEM (Building the future of Latin America: engaging women into STEM) is a project funded under European Union ERASMUS + Capacity-building in Higher Education Programme (598923-EPP-1-2018-1-ES-EPPKA2-CBHE-JP). The European Commission support for the production of this publication does not constitute an endorsement of the contents which reflects the views only of the authors, and the Commission cannot be held responsi­ble for any use which may be made of the information contained therein.
Psychometric performance of the perceived stigma of substance abuse scale (PSAS) among patients on methadone maintenance therapy in Vietnam
Creators: name: Bui, Q.
name: Pence, B.W.
name: Gaynes, B.N.
name: Mughal, A.Y.
name: Stockton, M.A.
name: Greene, M.C.
name: Go, V.
Publisher: name: Elsevier Ireland Ltd
Year: 2021

description: Background: People who inject drugs (PWID) and patients on methadone maintenance therapy (MMT) face severe stigma and discrimination. However, there are limited measures assessing stigma towards individuals with substance use disorders or MMT patients, particularly in Vietnam, and few studies have examined the psychometric properties of existing measures. This study aims to examine the performance of the eight-item Perceived Stigma of Substance Abuse Scale (PSAS), created in the United States, among a population of MMT patients in Vietnam. Methods: A cross-sectional survey was conducted among 400 adult patients enrolled in an urban MMT clinic. Substance use stigma was measured using the PSAS. We conducted confirmatory factor analysis (CFA) and assessed construct validity, reliability and known-group validity. Results: The original eight-item scale was unidimensional, but yielded mixed goodness-of-fit indicators. Ultimately, dropping two items and allowing the errors of the items related to childcare to correlate improved the goodness-of-fit indicators. (RMSEA = 0.025; CFI = 0.999; and SRMR = 0.018). The shortened scale demonstrated acceptable reliability (Cronbach's α = 0.766). The mean stigma scores were significantly higher among individuals not working, but did not significantly vary by length of time in MMT, marital status, education attainment, HIV status, depression, concurrent injection drug use or missed methadone dose. Conclusions: The shortened six-item scale demonstrated good construct validity and acceptability reliability, but it did not demonstrate many a priori hypothesized known-group validity associations. Further research should consider a mixed-methods validation approach.
Additional file 3 of Valsartan in combination with metformin and gliclazide in diabetic rat model using developed RP-HPLC method
Creators: name: Patra, Rasmita
name: Kollati, Yedukondalu
name: NS, Sampath Kumar
name: Dirisala, Vijaya R.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 3: Supplementary Fig. 3. Valsartan effect on diabetic rats in presence of Gliclazide. Mean plasma concentrations (n = 6, μg.ml−1).
title: Atlas des DOM. - La Réunion - Planche 30 : Commerce : notice, page 1 "I. Le commerce intérieur"
Creators: name: Lefèvre, Daniel
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2017
Subjects: commerce de détail
production agricole
répartition de la population
activité économique
secteur tertiaire
exportation
chaîne commerciale
circuit de distribution
commerce
commerce intérieur
commerçant
relation ville campagne

description: Présente les circuits commerciaux, la répartition géographique et ethnique par commune des commerçants ainsi que les zones d'influence commerciale du commerce intérieur. Quatre tableaux et un carton appuient ces propos : un tableau donne le nombre d'habitants par unité commerciale, un tableau donne l'importance relative des commerces à Saint-Denis et à Saint-Pierre, un tableau donne l'importance des commerces au Port, à Saint-Louis et à Saint-André un tableau donne l'importance des commerces à Saint-Benoît, à Saint-Paul, au Tampon et à Saint-Joseph, un carton montre l'essentiel des achats directs de vêtements qui sont effectués dans les centres principaux ou secondaires les plus proches du domicile.
description: Relation: http://www.nakala.fr/data/11280/12b4e1fb
description: Relation: http://www.nakala.fr/data/11280/c613c84b
description: Relation: http://www.nakala.fr/data/11280/ef77fb0e
description: Relation: http://www.nakala.fr/data/11280/819f4942
description: Coverage: La Réunion
description: Coverage: Le Port
description: Coverage: Saint-Paul
description: Coverage: Saint-Pierre
description: Coverage: Saint-Joseph
description: Coverage: Saint-Benoît
description: Coverage: Saint-André
description: Coverage: Saint-Denis
description: Coverage: Le Tampon
description: Coverage: Saint-Louis
description: Temporal: start=1972; end=1975;
Additional file 4 of Valsartan in combination with metformin and gliclazide in diabetic rat model using developed RP-HPLC method
Creators: name: Patra, Rasmita
name: Kollati, Yedukondalu
name: NS, Sampath Kumar
name: Dirisala, Vijaya R.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 4: Supplementary Fig. 4. Comparison of blood glucose level reduction between only Gliclazide and combinational administration (Gliclazide plus Valsartan) on both day 1 and 8.
Analytical Solutions for the Surface States of Bi$_{1-x}$Sb$_x$ ($0\le x \lesssim 0.1$)
Creators: name: Fuseya, Yuki
name: Fukuyama, Hidetoshi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Analytical solutions for the surface state (SS) of an extended Wolff Hamiltonian, which is a common Hamiltonian for strongly spin-orbit coupled systems, are obtained both for semi-infinite and finite-thickness boundary conditions. For the semi-infinite system, there are three types of SS solutions: (I-a) linearly crossing SSs in the direct bulk band gap, (I-b) SSs with linear dispersions entering the bulk conduction or valence bands away from the band edge, and (II) SSs with nearly flat dispersions entering the bulk state at the band edge. For the finite-thickness system, a gap opens in the SS of solution I-a. Numerical solutions for the SS are also obtained based on the tight-binding model of Liu and Allen [Phys. Rev. B, 52, 1566 (1995)] for Bi$_{1-x}$Sb$_x$ ($0\le x \le 0.1$). A perfect correspondence between the analytic and numerical solutions is obtained around the $\bar{M}$ point including their thickness dependence. This is the first time that the character of the SS numerically obtained is identified with the help of analytical solutions. The size of the gap for I-a SS can be larger than that of bulk band gap even for a "thick" films ($\lesssim 200$ bilayers $\simeq 80$ nm) of pure bismuth. Consequently, in such a film of Bi$_{1-x}$Sb$_x$, there is no apparent change in the SSs through the band inversion at $x\simeq 0.04$, even though the nature of the SS is changed from solution I-a to I-b. Based on our theoretical results, the experimental results on the SS of Bi$_{1-x}$Sb$_x$ ($0\le x \lesssim 0.1$) are discussed.
description: 11 pages, 12 figures
Additional file 1: of Pregnant womenâ s experiences with an integrated diagnostic and decision support device for antenatal care in Ghana
Creators: name: Ibukun-Oluwa Abejirinde
name: Douwes, Renate
name: BardajĂ­, Azucena
name: Abugnaba-Abanga, Rudolf
name: Zweekhorst, Marjolein
name: Roosmalen, Jos Van
name: Brouwere, Vincent De
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Question Guide: Client exit interviews. (DOCX 145 kb)
A mixed-methods process evaluation: Integrating depression treatment into hiv care in malawi
Creators: name: Go, V.
name: Pettifor, A.E.
name: Pence, B.W
name: Gaynes, B.N.
name: Udedi, M
name: Hosseinipour, M.C.
name: Minnick, C.E.
name: Stockton, M.A.
name: Mphonda, S.M.
name: Maselko, J.
name: Kulisewa, K.
Publisher: name: Johns Hopkins University Press
Year: 2021

description: Background: Depression is highly prevalent among people living with HIV in Malawi. Depression can undermine engagement in HIV care and worsen HIV morbidity and mortality. The Ministry of Health integrated a pilot depression management program into HIV care at 2 clinics. This program included a measurement-based care protocol for prescribing antidepressants and an adapted Friendship Bench psychotherapy protocol for providing problem solving. Early evaluations indicated successful integration of the initial stages of training and depression screening, diagnosis, and treatment initiation. This follow-up mixed-method investigation contextualizes our previous findings and shares insights from the implementation experience. Methods: We conducted a mixed-methods process evaluation drawing on both patient clinical data and qualitative interviews with patients and clinic staff. We focus on the following implementation outcomes: Fidelity, acceptability, and sustainability. Results: Although fidelity to depression screening and treatment initiation was high, fidelity to the follow-up treatment protocol was poor. Antidepressants and problem-solving therapy were acceptable to patients, but clinic staff found delivering treatment challenging given constrained human resources and infrastructure. The program was not sustained after the project. Key identified needs included substantial support to supervise the implementation of the program, continue to build and maintain the capacity of providers, integrate the program into the electronic medical records system, and ensure the availability of Friendship Bench counselors. Conclusions: Although initial steps were successful, sustained integration of this depression treatment program into HIV care in this setting met greater challenges. Implementation science studies that support both implementation and evaluation should recognize the potential for clinical implementers to rely on evaluation staff for clinical support and consider distancing evaluation staff from the actual program implementation. Further research is needed to test enhanced implementation strategies for integrating evidence-based mental health interventions into existing health care systems in a sustainable fashion, particularly in lowresource settings.
Action at a distance in classical uniaxial ferromagnetic arrays
Creators: name: Abraham, D. B.
name: Maciołek, A.
name: Squarcini, A.
name: Vasilyev, O.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We examine in detail the theoretical foundations of striking long-range couplings emerging in arrays of fluid cells connected by narrow channels by using a lattice gas (Ising model) description of a system. We present a reexamination of the well known exact determination of the two-point correlation function along the edge of a channel using the transfer matrix technique and a new interpretation is provided. The explicit form of the correlation length is found to grow exponentially with the cross section of the channels at the bulk two-phase coexistence. The aforementioned result is recaptured by a refined version of the Fisher-Privman theory of first order phase transitions in which the Boltzmann factor for a domain wall is decorated with a contribution stemming from the point tension originated at its endpoints. The Boltzmann factor for a domain wall together with the point tension is then identified exactly thanks to two independent analytical techniques, providing a critical test of the Fisher-Privman theory. We then illustrate how to build up the network model from its elementary constituents, the cells and the channels. Moreover, we are able to extract the strength of the coupling between cells and express them in terms of the length and width and coarse grained quantities such as surface and point tensions. We then support our theoretical investigation with a series of corroborating results based on Monte Carlo simulations. We illustrate how the long range ordering occurs and how the latter is signaled by the thermodynamic quantities corresponding to both planar and three-dimensional Ising arrays.
description: 36 pages, 19 figures
Introduction to Assessing Biodiversity: Bivalves of the Rio Grande Area
Creators: name: Schlichte, Julie
name: Walsh, Elizabeth
name: Zhuang, Vicky
Publisher: name: QUBES Educational Resources
Year: 2024

description: Learning to identify taxa is a key skill gained in many systematics classes. This module aims to introduce students to concepts and resources for identifying organisms and assessing species biodiversity. The activities use bivalve specimen and data from the Rio Grande stored in natural history collections. Students are given a few mystery specimens that they will attempt to identify, learn how to read labels commonly found with museum specimens and extract information from those labels to map bivalves along the Rio Grande.
Additional file 5 of Valsartan in combination with metformin and gliclazide in diabetic rat model using developed RP-HPLC method
Creators: name: Patra, Rasmita
name: Kollati, Yedukondalu
name: NS, Sampath Kumar
name: Dirisala, Vijaya R.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 5: Supplementary Fig. 5. Comparison of blood glucose level reduction between metformin alone and combinational administration (metformin plus Valsartan) on both day 1 and 8.
Simulation code for "Dynamic trait distribution as a source for shifts in interaction strength and population density"
Creators: name: Jackson, Zachary
Publisher: name: Zenodo
Year: 2024

description: This is the simulation code and data created for work published in an article for American Naturalist titled "Dynamic trait distribution as a source for shifts in interaction strength and population density". These code and figures were created by Dr. Zachary Jackson as a postdoctoral researcher at the University of Florida.
Low-energy excitations in electron-doped metal phthalocyanine from NMR in Li$_{0.5}$MnPc
Creators: name: Filibian, M.
name: Carretta, P.
name: Miyake, T.
name: Taguchi, Y.
name: Iwasa, Y.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: $^7$Li and $^1$H NMR and magnetization measurements in \lpc (Pc$\equiv$C$_{32}$H$_{16}$N$_8$), recently proposed as a strongly correlated metal, are presented. Two different low-frequency dynamics are evidenced. The first one, probed by $^1$H nuclei gives rise to a slowly relaxing magnetization at low temperature and is associated with the freezing of MnPc $S=3/2$ spins. This dynamic is similar to the one observed in pristine $β$-MnPc and originates from Li depleted chain segments. The second one, evidenced by $^7$Li spin-lattice relaxation rate, is associated with the hopping of the electrons along Li-rich chains. The characteristic correlation times for the two dynamics are derived and the role of disorder is briefly discussed.
description: 7 two-columns pages, 11 figures
Additional file 1: of Assessing the reliability and validity of the Danish version of Organizational Readiness for Implementing Change (ORIC)
Creators: name: Storkholm, Marie
name: Mazzocato, Pamela
name: Mesfin Tessma
name: Savage, Carl
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Organizational Readiness for Implementing Change (ORIC)â Danish version. (DOC 46 kb)
The Origin of a Chemically Enriched lya Absorption System at z=0.167
Creators: name: Chen, Hsiao-Wen
name: Prochaska, Jason X.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the first detailed analysis of the chemical abundances, ionization state, and origin of a partial Lyman limit system (N(\hI) ~ 10^{16} \cmjj) at low redshift (z=0.167 towards PKS0405-1219). Two galaxies at ~ 70 h^{-1} kpc projected distance to the QSO have been identified at the absorber redshift. We analyze an echelle spectrum of the QSO obtained with the Space Telescope Imaging Spectrograph and find that this absorption system exhibits associated lines produced by C^+, N^+, O^0, Si^+, Si^{++}, Si^{+3}, Fe^+, and Fe^{++}, and most interestingly, O^{+5} and N^{+4}. The results of our analysis show that the partial Lyman limit system traced by various ions is likely to be embedded in a collisionally ionized \ovi gas of larger spatial extent. Furthermore, the partial Lyman limit system appears to have a metallicity of {\em at least} 1/10 solar and most likely solar or super solar despite the fact that no luminous galaxies are seen within a projected distance ρ= 60 h^{-1} kpc to the QSO. Finally, adopting the temperature estimated for the hot gas T ~ 2.5\times 10^5 K and assuming a simple isothermal halo, we estimate that the galaxy or galaxy group that supports the extended gas may have a total mass ~ 1.5\times 10^{12} M_\odot and a gas number density \apl 3\times 10^{-5} cm^{-3}.
description: 18 pages, 1 figure. Accepted for publication in the ApJ Letters
Additional file 6 of Valsartan in combination with metformin and gliclazide in diabetic rat model using developed RP-HPLC method
Creators: name: Patra, Rasmita
name: Kollati, Yedukondalu
name: NS, Sampath Kumar
name: Dirisala, Vijaya R.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 6.
Jolly angler; or, Water side companion, containing an account of all the best places for angling, as as the tackle, baits & other requisites to form an expert angler
Creators: name: [Unknown]
Publisher: name: [London] : J. March
Year: 2018

description: "Containing an Account of all the best places for angling as well as the tackle, baits, & other requisites to form an expert Angler" -- Title page

Edition: 3d ed.
N=2 Topological Yang-Mills Theory on Compact Kähler Surfaces
Creators: name: Park, Jae-Suk
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study a topological Yang-Mills theory with $N=2$ fermionic symmetry. Our formalism is a field theoretical interpretation of the Donaldson polynomial invariants on compact Kähler surfaces. We also study an analogous theory on compact oriented Riemann surfaces and briefly discuss a possible application of the Witten's non-Abelian localization formula to the problems in the case of compact Kähler surfaces.
description: ESENAT-93-01 & YUMS-93-10, 34pages: [Final Version] to appear in Comm. Math. Phys
Jolly angler: or, Water side companion
Creators: name: [Unknown]
Publisher: name: London : J. March
Year: 2018

description: "Containing an Account of all the best places for angling, as well as the tackle, baits, & other requisites to form an expert Angler; with a correct description of tying hooks, making artificial flies, repairing tackle, &c." -- Title page