cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Impact of SafeCare Parent-Child Interaction Module on Father-Child Interactions: An examination of an observational measure
Creators: name: Patterson, Alexandria
Publisher: name: Georgia State University
Year: 2017

description: 
Child maltreatment is classified as the abuse (physical, emotional, and sexual) or neglect of a minor (Center for Disease and Control [CDC], 2015). The number of child maltreatment victims has fluctuated over the past five years, with recent reports indicating an estimate of 683,000 victims in 2015, an increase of 3.8% since 2011 (US Department of Health and Human Services, 2017). Low-quality parent-child interactions throughout childhood has been identified as having a significant negative impact on a child’s developmental outcomes thus children who have high-quality interactions with their caregivers are less likely to be victims of child maltreatment (Landry, Smith, Swank, & Guttentag, 2008).  Few studies focus solely on fathers and their interactions with their children, especially in populations at higher risk for perpetuating child maltreatment despite fathers being recognized as having an important role in their child’s social and behavioral development (Scourfield, 2014). SafeCare, an evidence-based program tested mostly with mothers, addresses target skills across child activities and behavior management, has shown to be effective in reducing physical abuse and neglect in children aged 0-5 (Chaffin et al., 2013). This study is a secondary data analysis from an NIH-funded project conducted between 2013 and 2016 (see Self-Brown et al., 2015). As a means of preventing child maltreatment, we focus on improving the quality of interactions children have with their fathers by targeting specific teachable skills. This study focused specifically on the analysis of an observational measure of father-child interaction to examine whether the Parent-Child Interaction skills of father-child dyads in the intervention group fathers improve after participation in SafeCare compared to the control group fathers. This hypothesis was not supported, likely due to limited power, given the poor participation of study participants in this observational measure.
Pathologic and Prognostic Implications of Incidental vs. Non-Incidental Gallbladder Cancer: A 10-Institution Study from the U.S. Extrahepatic Biliary Consortium
Creators: name: Le, Nina
Publisher: name: Georgia State University
Year: 2017

description: BACKGROUND: Most gallbladder cancers (GBC) are discovered incidentally after routine cholecystectomy. The relationship between the method of diagnosis and disease stage, treatment, and prognosis are not known.
METHODS
Patients with GBC who underwent resection at 10 institutions from 2000-2015 were included. Patients diagnosed incidentally (IGBC) and non-incidentally (non-IGBC) were compared. Primary outcome was overall survival (OS).
RESULTS
Of 445 patients with GBC, 266 (60%) were IGBC and 179 (40%) were non-IGBC. Compared to IGBC, non-IGBC patients were more likely to have R2 (macroscopic residual disease) resections (43 vs. 19%; p<0.001), advanced tumor (T) stage (T3/T4: 70 vs. 40%; p<0.001), high grade tumors (50 vs. 31%; p<0.001), lymphovascular invasion (LVI: 64 vs. 45%; p=0.01), and positive lymph nodes (LN: 60 vs. 43%; p=0.009). Receipt of adjuvant chemotherapy was similar between the groups (49 vs. 49%). Non-IGBC was associated with worse median OS compared to IGBC (17 vs. 32 months, p<0.001), which persisted among Stage III patients (12 vs. 29 months; p<0.001), but not Stages I, II or IV. After adjustment of other adverse pathologic factors (grade, T-stage, LVI, margin, LN), adjuvant chemotherapy was associated with improved OS only in Stage III IGBC but not in non-IGBC.
CONCLUSION
Compared to incidental discovery, non-incidental gallbladder cancer is associated with reduced overall survival, which is most evident in Stage III disease. Despite being well-matched for other adverse pathologic factors, adjuvant chemotherapy was associated with improved survival only in Stage III patients with incidentally discovered cancer. This underscores the importance of method of diagnosis in gallbladder cancer and suggests that these two groups may represent a distinct biology of disease, and the same treatment paradigm may not be appropriate.
Development to learning process model to enhance democratic behavior for undergraduate students
Creators: name: Phinla, Wipada
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 390102
subject: Curriculum and pedagogy theory and development

description: This research aimed to: 1) development of learning process model to enhance democratic behavior for Undergraduate Students; 2) determine the effectiveness of using development of learning process model to enhance democratic behavior for Undergraduate Students. The sample used in this research, drawn according to the purposive sampling, included 52 second year undergraduate students majoring in social studies, Facultyof Education, Thaksin University, Songkhla Campus during the second semester of the 2016 academic year, who have enrolled in Human Rights Education course. The research instruments included lesson, achievement tests in the Human Right Education course, and a form for assessing students’ democraticbehavior.The data were analyzed using such statistics as arithmetic mean, standard deviation (S.D.), the t-test dependent and content analysis.
Detection of co-formulants in plant protection products using liquid chromatography coupled to high resolution mass spectrometry
Creators: name: Hakme, Elena
name: Bhattarai, Bina
name: Poulsen, Mette Erecius
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Co-formulants are substances that are used in plant-protection products (PPPs) to give the product the necessary functions for field application. However, there is a data gap in terms of residues of co-formulants in food while assessment studies of consumer exposure to co-formulant residues in food are limited. Therefore, the aim of this study is to identify co-formulants used in PPPs and assess the presence of co-formulant residues in tomato samples that have been sprayed with these PPPs in the field. The analysis of PPPs and field-treated tomato samples was conducted using liquid chromatography coupled with high-resolution mass spectrometry (LC-Q-Orbitrap-MS) and a non-targeted analytical workflow. Eight products contained N,N-dimethyldecylamine N-oxide, while bis(2-ethylhexyl)amine was detected in six of the testedPPPs. Residues of bis(2-ethylhexyl)adipate and 16-hydroxyhexadecanoic acid were detected in tomatoes. The findings of this study demonstrate the possible presence of potentially hazardous co-formulant residues in food.
Neighborhood Factors Associated with Mental Disorder among Children in the USA: Evidence from National Survey of Children's Health 2011/12
Creators: name: Dahal, Sushma
Publisher: name: Georgia State University
Year: 2017

description: INTRODUCTION: Neighborhood factors affect mental health of children. There are not many studies done on neighborhood conditions and common childhood mental disorders using national level data in the US. This study aims to study the association between neighborhood characteristics and mental disorder among children in the US by analyzing nationally representative data.
METHODS: Data on children aged 6-17 years from 2011/12 national survey of children’s health was analyzed. Primary dependent variable was current diagnosed mental disorder that was based on the diagnosis of at least one of the attention deficit hyperactivity disorder (ADHD), behavioral or conduct problem, depression and anxiety problem among children. Five neighborhood conditions (neighborhood amenities, neighborhood distracting element, supportive neighborhood, neighborhood safety, and school safety) were the independent variables. Analysis was conducted using bivariate and multivariable logistic regression at 95% CI.
RESULTS: All the neighborhood conditions were significantly associated with current diagnosed mental disorder among children. In the multivariable model, children living in neighborhood perceived to be not supportive by parents/guardians had greater odds of mental disorder (OR 1.37, 95% CI:1.10-1.71) compared to children living in supportive neighborhood. Other noticeable factors associated with mental disorder among children were father’s and mother’s mental health, and number of adverse childhood experiences (ACEs).
CONCLUSION: Neighborhood level interventions should be a part of broad interventions designed to improve mental health of children. Besides, assessment of conditions of a child’s neighborhood, parents’ perception of neighborhood social support, father’s and mother’s mental health, and adverse childhood experiences can be helpful in evaluating childhood mental disorders as well as in planning neighborhood level interventions.
Association Between Concussions and Suicidal Behaviors
Creators: name: Wangnoo, Tahira
Publisher: name: Georgia State University
Year: 2017

description: Background: While there is increasing evidence on the long-term risks associated with concussions, the association between hopelessness, suicidal ideation, suicidal planning and suicidal attempts in high school aged adolescents has not yet been explored.  The current study aims to estimate the association between concussions and suicidal behaviors in Utah high school students.
 
Methods: We analyzed the 2013 Utah Youth Risk Behavior Survey (YRBS), a state, representative survey of 2,195 9th through 12th grade high school students.  Bivariate and multivariable logistic regressions controlling for race/ethnicity, sex, grade, and alcohol use were conducted to evaluate the adjusted odds ratio and 95% confidence interval (CI) of suicidal behaviors comparing students exposed to one or more concussions to those unexposed.
 
Results: Students with self-reported concussion exposure had significantly greater odds of reporting feeling sad of hopeless (OR = 1.7; 95% CI 1.4, 2.2), suicidal ideations (AOR =2.0; 95% CI 1.4, 2.7), suicidal planning (AOR= 2.0; 95% CI 1.4, 2.8) and suicidal attempts (OR=2.3; 95% CI 1.4, 3.7) after controlling for grade, sex, race and alcohol-use. 
 
Discussion:  Results from this study suggest that high school students who have suffered from a concussion are more likely to report suicidal behaviors, compared to high school students who did not report a concussion.  Given the results, concussion prevention education efforts in high schools are warranted. In addition, it’s imperative to educate parents, teachers, and health professionals how to recognize a concussion and any possible mental health outcomes as a result. Future longitudinal research is needed to better understand temporality of this association.
Preprocessing Strategies for Multiplex Bead Assay Data for Use in Quantitative Trait Loci Analysis
Creators: name: McDonald, Circe
Publisher: name: Georgia State University
Year: 2017

description: INTRODUCTION:  
Host genetic variants are known to impact infectious disease susceptibility and outcomes. However, the genes underlying these impacts are not well characterized. Multiplex bead assays (MBA) provide an affordable and rapid means of large scale screening for multiple phenotypic measures of immune response. Transformation and normalization approaches for MBA data have not been agreed upon, especially concerning screening applications.
AIM: 
To compare preprocessing techniques in improving validity of quantitative loci trait analyses which utilize MBA phenotypic data with high levels of predictor technical variability using experimental data.  
METHODS:
This research uses primary dendritic cells derived from a set of sixty-one genetically diverse mouse strains to study activation response of an antiviral pathway (RIG-I). Primary outcomes were IFN? and IFN? secretion following RIG-I agonist treatment. Multiple transformation and normalization approaches were used to estimate true IFN? and IFN? responses. Evaluation criteria included three quantitative measures (tail length, kurtosis, skewness) and three qualitative measures (QQ-plot, Bland-Altman plot, Mean-SD plot).
RESULTS: 
Most qualitative measures and quantitative measures found log transformation with quantile normalization was most appropriate for normalizing data and reducing technical variability between batches and replicates. Unfortunately, no statistically significant (? = 0.90) loci of interest were identified with this normalized data.
DISCUSSION: 
The data used to test these methods had notable limitations, mainly only two phenotypic markers and dramatic variability in both technical and biological replicates. While normalization and transformation techniques did ameliorate these issues, additional approaches such as mixed effects modeling may be able to further improve these types of analysis.
Effect of intranasal esketamine on cognitive functioning in healthy participants: a randomized, double-blind, placebo-controlled study
Creators: name: Morrison, Randall
name: Fedgchin, Maggie
name: Jaskaran Singh
name: Gerven, Joop Van
name: Ark, Peter Van Der
name: Wajs, Ewa
name: Liwen Xi
name: Zannikos, Peter
name: Drevets, Wayne
Publisher: name: F1000Research
Year: 2016

description: Background: This randomized, double-blind, 2-period crossover study assessed the effect of intranasal esketamine, the S-enantiomer of ketamine racemate, on cognitive function in healthy participants.

Methods: Adults (18-49 years, inclusive) were randomized to intranasal esketamine (84-mg, single-dose; period 1) and placebo (period 2), or vice versa. Primary measures of cognitive functioning included 5 tests of Cogstate® computerized battery.

Results: Total 24 participants were randomized and analyzed. Esketamine was associated with significantly greater cognitive performance impairment (all tests) than placebo at 40 minutes postdose; LS mean (SE)  (placebo vs. esketamine) were – Detection: 2.44 (0.014) vs. 2.51 (0.014), p=0.0011; Identification: 2.64 (0.009) vs. 2.68 (0.009), p=0.0006; One Card Learning: 1.09 (0.021) vs. 0.99 (0.021), p=0.004; One Back: 2.75 (0.012) vs. 2.8 (0.012), p=0.0017; Groton Maze Learning Test: 38.5 (2.45) vs. 59.7 (2.51), p<0.0001; there was no significant difference at the 2-, 4-, or 6-hour postdose assessments. Mental Effort Scale and Karolinska Sleepiness Scale (LS mean [SE], 40 minutes postdose; placebo vs. esketamine) were: 2.74 (0.35) vs. 7.01 (0.358) and 3.85 (0.344) vs. 6.32 (0.344) respectively (p<0.0001, each). Following esketamine administration, most common treatment-emergent adverse events (n >25%) were: dizziness (66.7%), nausea (37.5%), disturbance in attention (29.2%) and fatigue (29.2%).

Conclusions: Overall, esketamine was associated with greater cognitive performance decline versus placebo at 40 minutes postdose, which returned to comparable levels by 2-hour postdose. These cognitive performance reductions coincided with greater effort required to complete the test battery. Single intranasal dose of esketamine was safe and well-tolerated with no sedation evident 4-hour postdose.
Medicaid Expansion and Hospital Closures: Examining Hospital, County, and State Effects in the Wake of the Affordable Care Act
Creators: name: Allen, Jacob
Publisher: name: Georgia State University
Year: 2017

description: INTRODUCTION: Since 2010, there has been a wave of hospital closures and mergers across the United States. These closures have likely impaired access to ambulatory care services for many communities, particularly those in which only one hospital is present. Given that decisions to expand Medicaid were state-specific, there may be differences in number and type of hospital closures between states that expanded and did not expand Medicaid
AIM: The present study aims to investigate the association between state level Medicaid expansion and short-term hospital closures from 2010-2016 using multilevel modeling of hospitals, counties, and states. This analysis aims to control for hospital differences, county demographics, and state insurance market factors.
METHODS: Hospital level data was obtained from the Center for Medicaid and Medicare Services. For contextual county effects, small area health insurance, income, and poverty estimates were included (U.S. Census 2013). State decisions on Medicaid expansion and state-level insurance market data was also assembled and analyzed. Multilevel models were estimated in STATA gllamm.
RESULTS: Medicaid non-expansion was not associated with a greater risk of hospital closure once included in the multilevel model. Further, rural vs. urban status was not predictive of hospital closure. Smaller hospitals, nonprofit hospitals, and hospitals with a history of ownership change were associated with closure risk. Critical access hospital status was a protective factor against closure.
DISCUSSION: Local, state, and federal policies supportive of small and nonprofit hospitals may be beneficial in preventing more hospital closures in the coming years. Further, in-depth financial research and increased awareness of both the historical and current trends in hospital closures is recommended for researchers and policymakers.
Brain structural features that characterize the inattentive and combined subtypes of ADHD
Creators: name: Saad, Jacqueline
name: Griffiths, Kristi
name: Kohn, Michael
name: Clarke, Simon
name: Williams, Leanne
name: Mayuresh Korgaonkar
Publisher: name: F1000Research
Year: 2016

description: ADHD is clinically characterized by hyperactive/impulsive and/or inattentive symptoms which determine diagnostic presentation (i.e. subtypes) as: Predominantly Inattentive (ADHD-I), Predominantly Hyperactive-Impulsive (ADHD-HI) and Combined (ADHD-C).

 	Differences in symptom and cognitive profiles between these subtypes suggest that they may have divergent biological bases, and may in fact be distinct conditions. There is a need for novel objective brain markers to better characterize the biological basis of ADHD subtypes. Structurally and functionally connected brain regions tend to exhibit co-ordinated fluctuations in grey matter volume over time due to mutually trophic influences. Differences in grey matter structural covariance and network properties may underlie the phenotypic differences between ADHD subtypes.
 The goal of this study was to investigate structural brain features that may characterize the combined (ADHD-C)  and inattentive (ADHD-I) ADHD subtypes
Risky Behaviors of Ugandan Youth in  Vocational Training Compared to Traditional Education
Creators: name: Buchongo, Portia
Publisher: name: Georgia State University
Year: 2017

description: INTRODUCTION: Formal education in sub-Saharan Africa has been found to decrease the risk of HIV infection among youth. However, vocational skills training has been used as an alternative for youth to gain employment. Yet, little is known about the types of risk behaviors prevalent among youth who enroll in vocational skills training programs.
AIM: The purpose of this study is to examine risk behaviors such as alcohol use, lack of condom use, sex with multiple partners, and transactional sex among youth living in the slums who participate in vocational skills training. The relationship of personal characteristics such as hopefulness and participation in vocational training programs will also be explored.
METHODS: Analyses were conducted using survey data based on a cross-sectional study of youth ages 12-18 years (N=1134), living in the slums of Kampala, that were surveyed in the Spring of 2014. The study sample included youth who had at least some formal education or higher and were compared to youth who had at least some formal education and participated in vocational skills training (N=1059). Alcohol use, lack of condom use, sex with multiple partners, and engaging in transactional sex were the primary risk factors of interest. Five multivariable logistical regression models were used to examine the risk behaviors and hopefulness in its associated with youth who participated in vocational skills training. Multivariable analysis stratified by gender was also conducted.
RESULTS: Youth who participated in vocational skills training had completed primary education (62%) and were predominately female (80%). Youth who participated in vocational skills training were less likely to report alcohol use (AOR 0.38; 95% CI 0.20, 0.70) and more likely to report feeling hopeful often (AOR 1.73; 95% CI 1.07, 2.97).
DISCUSSION: Youth participation in vocational training is association with youth being less likely to use alcohol and youth feeling hopeful often compared to youth who do not participate in vocational training. Vocational skills training may be a viable strategy for reducing some risk behaviors. However, further research on this group and strategy for risk reduction is needed to assess the impact of these programs on youth behaviors.
Examining how protein sampling impacts the convergence of relative binding free energy calculations
Creators: name: Mobley, David L
name: Abel, Robert
name: Lingle Wang
name: Lim, Nathan
Publisher: name: F1000Research
Year: 2016

description: In this talk, I discuss our historical work applying binding free energy calculations to a series of simple model binding sites of progressive difficulty, then move on to discuss work currently in review on applying alchemical relative binding free energy calculations to a series of simple ligand mutations in the T4 Lysozyme model binding site. While the ligand mutations are simple, they induce a conformational change in the protein that poses a challenging test for these calculations, as I discuss in these slides. Likely this will form a good test case for applications of relative binding free energy calculations to problems involving modest protein conformational change.
Supplementary document for Mode division multiplexing on an InP membrane on silicon - 5952698.pdf
Creators: name: Wang, Yi
name: Wei, Yihui
name: Calzadilla, Victor Manuel Dolores
name: Williams, Kevin
name: Smit, Meint
name: Dai, Daoxin
name: Jiao, Yuqing
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Efecto de la depredación en la sucesión de las comunidades bentónicas sésiles en un puerto de Yucatán, México
Creators: name: Gómez-Bretón, V
name: Palomino-Alvarez, L.
name: León-Deniz, L.
name: Simoes, N.
name: Suárez-Mozo, N
name: Guerra-Castro, E
Publisher: name: Zenodo
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Ecology
subject: Ecology/trends
subject: Ecology/classification
subject: Ecology/education
subject: Animal ecology
subject: Aquatic ecology
subject: Fauna
subject: Marine fauna
subject: Species
subject: Invasive species
subject: Benthic ecosystem
subject: Marine biology
subject: Marine ecosystem
subject: Marine biota
subject: Marine Biology
subject: Marine biodiversity
subject: Marine biology
subject: Marine organism
subject: Fishes
subject: ITIS: 169190
subject: WoRMS : 159239
subject: GBIF : 2392546
subject: GBIF : 2394320
subject: GBIF : 2382537
subject: WoRMS : 159797
subject: WoRMS : 126241

description: Descubre más información sobre datos, investigaciones científicas, colecciones científicas y grupos de trabajo dedicados al estudio y conservación de la biodiversidad marina en https://www.bdmy.org.mx/

Discover more information about data, scientific research, scientific collections and working groups dedicated to the study and conservation of marine biodiversity at https://www.bdmy.org.mx/
Rates of Smoking and Visitations to Healthcare Facilities among People Living with HIV in Higher-risk vs. Lower-risk areas in Atlanta, Georgia
Creators: name: Carter, Brittani
Publisher: name: Georgia State University
Year: 2017

description: INTRODUCTION: The rate of smoking is significantly higher among people living with HIV (PLWH) in comparison to the general population (CDC, 2017b; Humfleet et al., 2009). Tobacco use among PLWH heightens the risk for HIV-related symptoms and is a pertinent public health issue. Smokers living with HIV are also more likely to develop non-AIDS-related illness in comparison to non-smokers living with HIV. Smoking cessation interventions are desperately needed to cater towards PLWH. This warrants the need for patient-provider interactions in healthcare facilities regarding smoking cessation.
AIM: To document rates of smoking and visitations to healthcare facilities among persons living with and without HIV in higher vs. lower-risk areas and to examine associations among healthcare visitations, stressors, and smoking in these sub-samples (i.e., PLWH in higher-risk areas, PLWH in lower-risk areas, people without HIV in higher-risk areas, people without HIV in lower-risk areas).
METHODS: Secondary analyses were conducted using data from a network-based, HIV endemic study that was conducted in Metro Atlanta (Rothenberg, Dai, Adams & Heath, 2017). The study included 927 participants from 10 Atlanta zip codes (5 lower-risk and 5 higher-risk based on reported HIV cases). Participants provided information on their smoking status and healthcare visitations, as well as whether they had experienced several stressors (e.g., violence, homelessness, being threatened with a weapon, lack of transportation). Descriptive analyses and frequency distributions were conducted and presented on key variables. Logistic regression analyses were conducted to examine associations between key variables and smoking.
RESULTS: Overall, the rate of smoking was quite high in this study. Seventy-four percent of the sample smoked, which is almost five times the smoking rate among the general adult U.S. population (CDC, 2016a). The smoking rate was strikingly high among PLWH in the higher-risk areas (95%). In unadjusted analyses, participants who were older, male, homeless, and do not drive their own car were more likely to smoke. In the adjusted analyses age, gender, and lack of transportation remained significant predictors of smoking. Visitations to healthcare facilities were not significantly associated with smoking or other variables in this study.
DISCUSSION: Smoking appears quite common among PLWH, especially those living in higher-risk areas. This study provided important information on the extent to which persons living with and without HIV in higher and lower-risk areas of Atlanta are receiving healthcare services, as well as how demographic factors and stress relate to smoking in these sub-samples. Future research is needed to develop and disseminate effective smoking cessation programs among smokers living with HIV.
Physical Dating Violence in Georgia: A Growing Disparity among Hispanic Youth
Creators: name: Knott, Britni
Publisher: name: Georgia State University
Year: 2017

description: Background: Nationally representative data of high school students in the U.S. indicate that levels of physical dating violence are higher among students in Georgia than in most states. This study seeks to understand the increased risk for physical dating violence among youth in Georgia and make recommendations for prevention and interventions.

Methods:
Analyses were conducted using the 2013 Youth Risk Behavior Survey, a nationally representative dataset sampling of high school students in grades 9-12 in the United States. Data from a total of 13,583 adolescents were used in the study. Physical dating violence was defined as reporting being hit, slammed into something, or injured with an object or weapon on purpose by someone they were dating or going out with among students who dated or went out with someone during the 12 months before the survey. Cross-sectional analyses of the prevalence of physical dating violence victimization by demographic characteristics will be conducted.

Results:
In the U.S. overall, 10.3% of high school students report any physical dating violence. Among the 38 states including data on physical dating violence in 2013, the state of Georgia ranked third highest (12.4%) only preceded by Louisiana (14.8%) and Arkansas (13.8%) for reports of physical dating violence. In Georgia, physical dating violence did not differ by grade level or by sex. However, in terms of race/ethnicity, Hispanic youth (18.1%) were significantly more likely than African American youth (9.6%) or of white youth (10.7%) to report physical dating violence.

Conclusion:
The state of Georgia has high levels of physical dating violence among high school youth and Hispanic high school students are more likely to report physical dating victimization compared to their peers. Culturally specific risk factors and influences may be an important factor for public health professionals and policy makers to explore to reduce the health disparity and adverse health outcomes associated with dating violence among youth.
Association Between Community Transition and Independence and Control Over Life: Analysis of Georgia's Money Follows the Person Program
Creators: name: Sulaiman, Farah Naz
Publisher: name: Georgia State University
Year: 2017

description: INTRODUCTION: The growing proportion of the elderly population and individuals with disabilities is increasing the demand for institutional long-term care. The majority of nursing home residents desire to exercise control over their lives and to have independence in activities of daily living, but nursing home care is often associated with loss of control and independence among its residents. Money Follows the Person (MFP) is a rebalancing strategy to contain cost for long-term care and enhance consumer choice for elderly individuals and individuals with disabilities. The MFP program helps qualified individuals living in institutions make the transition to life in the community.
AIM: This study is aimed to explore the association of community transitions and the measures of independence and control over life among MFP participants who have relocated from institutions to the community.
METHODS: Data from Georgia’s MFP participant survey from 2008 to 2015 were used to examine the association between community transition and measures of control and independence before transition and 12 months after transition. McNemar’s test was used to measure the before and after transition differences. Odds ratios and 95% confidence intervals were reported to determine the correlation of study measures with age, sex and disability type.
RESULTS: The analysis for 664 MFP participants (54.4% male and 45.6% female) surveys in the state of Georgia found a significant increase in 13 out of 15 measures of independence and control over life (e.g., being able to pick the place of residence, go to bed when want to, choose the type of food to eat, have privacy to talk on telephone, do paid/voluntary work and others) after transition, attributed to community transitions (p-value
DISCUSSION: Results suggested that relocating individuals with disabilities into the community can help increase perceived control and independence and reduce the limitation of choice, providing insight for policy makers to strengthen programs that can have a meaningful impact on cost-containment and quality of life for elderly people and for individuals with disabilities.
Diversidad de una comunidad bentónica asociada a una torre petrolera en el sur del Golfo de México
Creators: name: Hernández-Solis, Pablo Alberto
name: Pérez-Botello, Antar Mijaíl
name: León-Deniz, Lorena Violeta
name: Simoes, Nuno
Publisher: name: Zenodo
Year: 2022
Subjects: subject: Distribution
subject: Animal Distribution
subject: Benthos
subject: Ecological community
subject: Fauna
subject: Marine fauna
subject: Genetic diversity
subject: Biological diversity
subject: Animal behaviour
subject: Animal ecology
subject: Marine biology
subject: Marine ecosystem
subject: Marine biota
subject: Marine Biology
subject: Marine biodiversity
subject: Marine biology
subject: Marine organism
subject: Taxonomy
subject: Organism
subject: Aquatic organism

description: Descubre más información sobre datos, investigaciones científicas, colecciones científicas y grupos de trabajo dedicados al estudio y conservación de la biodiversidad marina en https://www.bdmy.org.mx/

Discover more information about data, scientific research, scientific collections and working groups dedicated to the study and conservation of marine biodiversity at https://www.bdmy.org.mx/
Prediction of Disease Status Based on MRI Brain Scans Using Sparse Principal Component Analysis
Creators: name: Vashi, Tejal
Publisher: name: Georgia State University
Year: 2017

description: INTRODUCTION:  Alzheimer’s Disease is a neurodegenerative disorder that affects millions of individuals worldwide and the association of brain regions to diagnosis is not presently known. Current methods for diagnosis are not sufficient, with the only true method for knowing if an individual has Alzheimer’s Disease being a post mortem analysis of brain tissue. Due to the high dimension of data, a classic principal component analysis to determine which variables to include in a model would not suffice. Sparse Principal Component Analysis deals with the limitations of Classic PCA and can produce which variables are highly correlated to include.
 
AIM: Compare the results of logistic regression, classic principal component analysis, and sparse principal component analysis to determine the variables to include in a model to differentiate between Mild Cognitive Impairment and Alzheimer’s Diagnosis.
 
METHODS: We analyzed brain scans from the Alzheimer’s Disease Neuroimaging Initiative.  Variables were predefined by the dataset by individual. We used these variables to run a regular logistic regression on all the variables, ran classic PCA on every stepwise increase in components included in the model, and finally ran the Sparse PCA model, comparing error rate to differentiate between the models and select the variables to include.
 
RESULTS:  We identified the error rate for every model, with SPCA with 8 components and a tuning parameters of 6 having the lowest, and then the variables included in that model were selected as the variables for prediction.
 
DISCUSSION: By applying this method to high dimensional brain scan data, we identified 59 variables to include in the model. Majority of these 59 variables agreed with the current literature for association with Alzheimer’s Disease.
Project Learning Garden: A Systematic Review of the Effectiveness of the Evaluation Techniques on School Gardens
Creators: name: Kavanaugh, Kasey
Publisher: name: Georgia State University
Year: 2017

description: Introduction: For decades, school gardens have been on the rise, globally. These programs are all-encompassing programs that provide hands-on activities, such as planting and harvesting fruit and vegetables, with preparing and cooking foods which grow in the garden. There are not many studies that have looked into these school gardens, let alone how these school gardens get evaluated. The aim of this systematic review is to examine how intensely school gardens get assessed and how useful their evaluation tools can be.
Methods: Studies chosen for this review included peer-reviewed journal articles, found on PubMed, assessing the impact of learning gardens on elementary and middle school students. The items found focused on the change in children's attitude toward, preference for, knowledge and consumption of fruit and vegetables, along with their progress in school. The articles were not limited to date or location; therefore materials from other countries were included. From the search results, the author obtained eight full-text articles.
Results: All of the eight papers reviewed showed a positive change in children's health and behaviors as a result of having access to a school gardening and getting an additional nutritional education. Three papers showed no change in the consumption of fruit and vegetables, while four articles found significant increases in preference for fruit and vegetables. Also, one paper showed no major differences in fruit and vegetable knowledge, while four papers showed marked improvement. All eight of the studies used surveys in some way, one study used a food diary, three studies focused on 24-hour recall, and one looked at lunchroom observations to evaluate the research.
Conclusion: This systematic review showed that school gardens have a positive effect on children’s attitude toward, preference for, knowledge and consumption of fruit and vegetables. The evaluation techniques used in these eight studies showed that surveys were more intensely written, as well as tools with less bias, were more efficient in determining the status of school garden effectiveness.
Design and Analysis of an Extreme-Scale, High-Performance, and Modular Agent-Based Simulation Platform
Creators: name: Breitwieser, Lukas Johannes
Publisher: name: arXiv
Year: 2025
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Multiagent Systems (cs.MA)
subject: Performance (cs.PF)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Agent-based modeling is indispensable for studying complex systems across many domains. However, existing simulation platforms exhibit two major issues: performance and modularity. Low performance prevents simulations with a large number of agents, increases development time, limits parameter exploration, and raises computing costs. Inflexible software designs motivate modelers to create their own tools, diverting valuable resources.
 This dissertation introduces a novel simulation platform called BioDynaMo and its significant improvement, TeraAgent, to alleviate these challenges via three major works.
 First, we lay the platform's foundation by defining abstractions, establishing software infrastructure, and implementing a multitude of features for agent-based modeling. We demonstrate BioDynaMo's modularity through use cases in neuroscience, epidemiology, and oncology. We validate these models and show the simplicity of adding new functionality with few lines of code.
 Second, we perform a rigorous performance analysis and identify challenges for shared-memory parallelism. Provided solutions include an optimized grid for neighbor searching, mechanisms to reduce the memory access latency, and exploiting domain knowledge to omit unnecessary work. These improvements yield up to three orders of magnitude speedups, enabling simulations of 1.7 billion agents on a single server.
 Third, we present TeraAgent, a distributed simulation engine that allows scaling out the computation of one simulation to multiple servers. We identify and address server communication bottlenecks and implement solutions for serialization and delta encoding to accelerate and reduce data transfer. TeraAgent can simulate 500 billion agents and scales to 84096 CPU cores.
 BioDynaMo has been widely adopted, including a prize-winning radiotherapy simulation recognized as a top 10 breakthrough in physics in 2024.
description: PhD Thesis submitted to ETH Zurich
The Impact of Race and Diabetes on Mortality among Breast Cancer Patients
Creators: name: Alim, Jibril
Publisher: name: Georgia State University
Year: 2017

description: INTRODUCTION: Breast cancer and Type 2 diabetes Mellitus are two chronic conditions that impact the lifespan and quality of life of women. Both diabetes and breast cancer have a disproportionate impact on African-American/Black women and it is reasonable to believe that Biological mechanisms or treatments for this co-morbid condition may have an antagonistic effect and impact the individual’s risk of mortality.
AIM: This study aims to address whether pre-existing diabetes occurs at different rates among African-American/Black women with breast cancer than White women, and if diabetes and race are associated with higher all-cause and breast cancer specific mortality among women.
METHODS: The US mortality linked data from the National Health Interview Survey (NHIS) 2006-2009, was used in the analysis. Cox proportional hazard regression was used to model and estimate the adjusted and unadjusted hazard ratios of the identified risk factors on mortality.
RESULTS: Diabetes and pre-existing diabetes (33.20% & 52.24%) were more prevalent among Black women with breast Cancer than Whites (13.87% & 39.82%). African-Americans experienced increased breast cancer specific mortality (HR: 1.564, 1.465-1.669 95%CI) than whites. Diabetes and Pre-diabetes were associated with increased risk of all-cause (HR: 1.60 & 1.329) and breast cancer specific mortality (HR: 1.37 & 1.177). Diabetes and pre-diabetes impacted all-cause mortality among Africans-Americans (HR: 15.757 & 13.658) differentially than Whites (HR: 1.377 & 1.079). Similarly, Diabetes and pre-diabetes impacted breast cancer-specific mortality among African-Americans (HR: 10.891 & 7.696) differentially than whites (HR: 1.125 & 0.850)
DISCUSSION: Diabetes and breast cancer was a more common comorbidity among Black women than Whites. Diabetes was associated with increased risk of all cause and breast cancer specific death. Race was found to have a significantly increase breast cancer specific mortality among diabetic individuals. Increased diabetes prevalence among Blacks may partially explain their higher breast cancer mortality rates.
Hospital Utilization Rate in The United States: Inpatient, Emergency Department and Outpatient Channels of Care Between 2005 and 2013
Creators: name: Bachtiar, Nur
Publisher: name: Georgia State University
Year: 2017

description: Objectives: To assess how three channels of hospital care – Inpatient (IP), Emergency Department (ED), and Outpatient (OP) visit rate changes between 2005 and 2013 and which factors are associated with the changes.
Methods: Using nation-wide data from Area Health Resource File (AHRF) 2015-2016 Release, we compare the mean hospital utilization between 2005 and 2013 and perform paired t-test to identify significant changes over time. We perform Wilcoxon two-sample test to determine if utilization changes between Medicaid-expanding states and non-expanding states have significant difference. To explore which factors can affect the utilization rate, we perform a multiple regression with thirteen factors of interest based on available data and the Andersen conceptual framework model. We stacked our 2005 and 2013 data and add time interaction variable with Medicaid expanding status to determine if the interaction between expansion and time is associated with the utilization rate in the adjusted regression model.
Results: We find significant changes in hospital utilization rate between 2005 and 2013. There is a 23.3% decrease in inpatient (IP) days of care rate and an increase of 4.4% in emergency (ED) and 12.9% in outpatient (OP) visit rates. When we separate the counties by Medicaid-expanding status, we find a significant difference on IP, and ED utilization rate between states that did and did not expand Medicaid over time. However, after we test it again by inserting expanding status and time interaction in our adjusted regression model, we did not find any significant association with any of the channels of care.
Factors that influence the utilization rate also vary, we find that area mortality rate, female and non-English Speaker population proportion, residential segregation, poverty, income inequalities, urban areas, and hospital availability are significantly associated with increased hospital utilization.
Conclusions: There are significant hospital utilization changes in crude, unmodeled hospital utilization rates between 2005 and 2013. However, despite the concerns of hospital overcrowding in Medicaid-expanding states, we find that after adjusting for all other factors, expanding states variable alone is significantly associated with the outpatient care utilization rate (?=-413.09, p = 0.0240), but does not have any significant association with Inpatient and Emergency department utilization rate. Which implies that in the six Medicaid expansion states, the outpatient care utilization rate was significantly lower than in the non-expanding states. Furthermore, when Medicaid expansion is interacted with time, it does not show any significant association with any channels of hospital utilization rate. Thus, the fears that Medicaid expansion would crowd the system are unfounded for these six states.
Effect of varenicline on cognitive function in non-smokers with schizophrenia
Creators: name: Kozak, Karolina
name: Barr, Mera
name: George, Tony
Publisher: name: F1000Research
Year: 2016

description: Background: Schizophrenia is associated with dysregulated central nicotinic acetylcholine receptors (nAChRs) that may relate to both the high smoking prevalence and pervasive cognitive deficits observed in this disorder. The nicotinic partial agonist varenicline, which is approved for smoking cessation, has been shown to enhance cognition in schizophrenia, but its effects in non-smokers are unknown. This study assessed the effects of varenicline on cognitive function in non-smoking schizophrenia patients compared to non-psychiatric controls.

Methods: In a randomized, placebo-controlled cross-over design, varenicline was administered at 3 doses (0, 1, 2 mg/day) over 3 days with a 1-week washout period in n=15 (mean age 40.13±11.1 years) schizophrenia patients and n=15 (mean age 39.80±10.6 years) non-smoking non-psychiatric controls. A cognitive battery was administered following the final dose of varenicline.

Results: A two-way ANOVA with diagnosis and dose as the between-subject factors was performed on all of the cognitive measures and revealed a significant effect of diagnosis on spatial working memory (F(1,84)=19.416, p<0.001), verbal memory (F(1,84)=22.068, p<0.001) and attention (F(1,81)=6.462, p<0.013). Overall patients performed better on the 1mg/day dose across these tasks, while controls perform better on the 2mg/day dose. There was no change in symptom severity with varenicline indexed by the PANSS.

Conclusions: These preliminary findings suggest potential dose dependent effects in a non-linear fashion in the patient group compared to controls, and are consistent with deficits in nAChR function in this disorder. These findings have implication for the treatment of cognitive dysfunction in schizophrenia.
Effect of ethylmalonic acids on acetylcholinesterase activity and expression in young rats
Creators: name: Pereira, Elen Gomes
name: T. P. Macan
name: W Fáveri
name: M. B. De Oliveira
name: L. W. Kist
name: E. L. Streck
name: G. C. Ferreira
name: M. R. Bogo
name: A. I. Zugno
name: P. F. Schuck
Publisher: name: F1000Research
Year: 2016

description: Patients suffering from short-chain acyl-CoA dehydrogenase deficiency (SCADD) and ethylmalonic encephalopathy (EE) present high concentrations of ethylmalonic acid (EMA) in tissues and body fluids. They present neurological heterogeneous alterations, including developmental delay and neuromuscular symptoms. In this work we evaluate the in vivo and in vitro effects of EMA on acetylcholinesterase (AChE) activity and its expression in cerebral cortex, striatum and hippocampus.