cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Discontinuous Galerkin method with higher degree finite difference compatibility conditions and arbitrary local and global basis functions
Creators: name: Jaskowiec, Jan
Publisher: name: figshare
Year: 2015
Subjects: subject: Computer Engineering
subject: 10301 Numerical Analysis
subject: FOS: Mathematics
subject: Mechanical Engineering
subject: FOS: Mechanical engineering

description: The paper focuses on the discontinuous Galerkin (DG) method in which the compatibility condition
on the mesh skeleton and Dirichlet boundary condition on the outer boundary are enforced with the help of one-dimensional finite difference (FD) rules, while in the standard approach those conditions are satisfied by the penalty constraints.

The FD rules can be of arbitrary degree and in the paper the rules are applied up to fourth degree. It is shown that the method presented in this paper gives better results in comparison to the standard version of the DG method. The method is based on discontinuous approximation, which means that it can be constructed using arbitrary local basis functions in each finite element. It is quite easy to incorporate some global basis functions in the approximation field and this is also shown in the paper. The paper is illustrated with a couple of two-dimensional examples.
Social and Economic Impact Analysis of Solar Mini-Grids in Rural Africa: A Cohort Study from Kenya and Nigeria
Creators: name: Carabajal, Amy Town
name: Orsot, Akoua
name: Moudio, Marie Pelagie Elimbi
name: Haggai, Tracy
name: Okonkwo, Chioma Joy
name: Jarrard, George Truett
name: Selby, Nicholas Stearns
Publisher: name: arXiv
Year: 2024
Subjects: subject: Systems and Control (eess.SY)
subject: Applications (stat.AP)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: This study presents the first comprehensive analysis of the social and economic effects of solar mini-grids in rural African settings, specifically in Kenya and Nigeria. A group of 2,658 household heads and business owners connected to mini-grids over the last five years were interviewed both before and one year after their connection. These interviews focused on changes in gender equality, productivity, health, safety, and economic activity. The results show notable improvements in all areas. Economic activities and productivity increased significantly among the connected households and businesses. The median income of rural Kenyan community members quadrupled. Gender equality also improved, with women gaining more opportunities in decision making and business. Health and safety enhancements were linked to reduced use of hazardous energy sources like kerosene lamps. The introduction of solar mini-grids not only transformed the energy landscape but also led to broad socioeconomic benefits in these rural areas. The research highlights the substantial impact of decentralized renewable energy on the social and economic development of rural African communities. Its findings are crucial for policymakers, development agencies, and stakeholders focused on promoting sustainable energy and development in Africa.
description: 43 pages, 16 figures, accepted by __Environmental Research: Infrastructure and Sustainability__
Assessing and targeting key lifestyle cardiovascular risk factors at the workplace: Effect on hemoglobin A1c levels
Creators: name: Lévesque, Valérie
name: Poirier, Paul
name: Després, Jean-Pierre
name: Alméras, Natalie
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Medicine

description: Purpose: Despite the key role played by lifestyle habits in the epidemic of type 2 diabetes (T2D), nutritional quality and physical activity are not systematically considered in clinical practice. The project was conducted to verify whether assessing/targeting lifestyle habits could reduce hemoglobin A1c (HbA1c) levels of employees. Methods: The intervention consisted of a 3-month competition among teams of five employees to favor peer-based support in the adoption of healthier lifestyle habits (Eat better, Move more, and Quit smoking) (n = 900). A comprehensive cardiometabolic/cardiorespiratory health assessment was conducted before and after the contest (nutrition/physical activity questionnaires, blood pressure, anthropometric measurements, lipid profile, HbA1c, fitness). HbA1c levels were used to identify individuals with prediabetes (5.7%–6.4%) or T2D (≥6.5%). Results: At baseline, 51% of the employees had increased HbA1c levels (≥5.7%). The HbA1c levels were associated with waist circumference, independently of body mass index. Subjects with prediabetes showed a higher waist circumference as well as a more deteriorated cardiometabolic profile compared to workers with normal HbA1c levels. After the intervention, employees with elevated HbA1c significantly reduced their HbA1c levels. Conclusion: Results suggest that assessing/targeting key lifestyle correlates of the cardiometabolic profile represents a relevant approach to target abdominal obesity and fitness with a significant impact on HbA1c levels. Key messagesThe prevalence of employees with prediabetes or undiagnosed type 2 diabetes (T2D) was rather high in our cohort, suggesting that, from a public health standpoint, identification of those individuals is not optimal.Employees with prediabetes or T2D showed a higher waist circumference and a more deteriorated cardiometabolic risk profile compared to those with normal HbA1c levels.The significant reduction in HbA1c levels observed in response to the 3-month intervention supports the notion that a program which assesses and manages cardiometabolic risk at the workplace by also focusing on key lifestyle factors (nutritional quality and physical activity levels) represents an interesting option to reduce the risk of developing diabetes among high-risk individuals or to improve glycemic control and related cardiometabolic risk in patients with T2D.
СИСТЕМНИЙ ПІДХІД ДО КЛАСИФІКАЦІЇ ПРАВОПРИПИНЯЮЧИХ ЮРИДИЧНИХ ФАКТІВ В МЕХАНІЗМІ ПРАВОПРИПИНЕННЯ
Creators: name: Kostruba, Anatoliy
Publisher: name: Zenodo
Year: 2018
Subjects: civi law
legal fact
legal interest
civil legal relations
content of legal relations

description: У даній книзі зібрані наукові праці відомих в Україні науковців, докторів юридичних наук, учнів, які багато років пліч-о-пліч працюють із високоавторитетним Вченим, знаного фахівця у сфері цивільного та договірного права. Праця друкується в рамках серії «НАШІ ЮВІЛЯРИ», яка започаткована та підтримується Науково-дослідним інститутом приватного права і підприємництва імені академіка Ф. Г. Бурчака НАПрН України. Книга розрахована на наукових та науково-педагогічних працівників вищих навчальних закладів і наукових установ, докторантів, аспірантів та студентів, а також на широке коло читачів.
Discontinuous Galerkin method with higher degree finite difference compatibility conditions and arbitrary local and global basis functions
Creators: name: Jaskowiec, Jan
Publisher: name: figshare
Year: 2016
Subjects: subject: Computer Engineering
subject: 10301 Numerical Analysis
subject: FOS: Mathematics
subject: Mechanical Engineering
subject: FOS: Mechanical engineering

description: The paper focuses on the discontinuous Galerkin (DG) method in which the compatibility condition
on the mesh skeleton and Dirichlet boundary condition on the outer boundary are enforced with the help of one-dimensional finite difference (FD) rules, while in the standard approach those conditions are satisfied by the penalty constraints.

The FD rules can be of arbitrary degree and in the paper the rules are applied up to fourth degree. It is shown that the method presented in this paper gives better results in comparison to the standard version of the DG method. The method is based on discontinuous approximation, which means that it can be constructed using arbitrary local basis functions in each finite element. It is quite easy to incorporate some global basis functions in the approximation field and this is also shown in the paper. The paper is illustrated with a couple of two-dimensional examples.
Additional file 1 of A complementary medicine student-led telehealth clinic: evaluating learning & teaching perceptions
Creators: name: Shew, Tracelee
name: Smith, Catherine
name: Connolly, Greg
name: Fleischmann, Michael
name: McLachlan, Craig S.
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Neuroscience
Biological Sciences not elsewhere classified
Science Policy
Mental Health

description: Supplementary Material 1
Additional file 1 of Glucocorticoid use in acute respiratory failure from pulmonary causes and association with early changes in the systemic host immune response
Creators: name: Al-Yousif, Nameer
name: Nouraie, Seyed M.
name: Broerman, Matthew J.
name: Zhang, Yingze
name: Suber, Tomeka L.
name: Evankovich, John
name: Bain, William G.
name: Kitsios, Georgios D.
name: McVerry, Bryan J.
name: Shah, Faraaz A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health
subject: Virology

description: Additional file 1: Table S1. Prior studies of glucocorticoid use in patients with acute respiratory distress syndrome (ARDS) or at-risk for ARDS due to severe pneumonia. Table S2. Conversion table for glucocorticoids [17]. Table S3. Clinical characteristics of ARDS and patients at-risk from a pulmonary insult who were excluded due to biomarker availability compared to patients who were included. Table S4. Clinical characteristics comparing patients with ARDS and patients at-risk for ARDS from a pulmonary insult included in the study. Table S5. Clinical characteristics comparing patients by pre-existing immunosuppression status. Table S6. Clinical characteristics by type(s) of glucocorticoid administered between baseline and follow-up samples. Table S7. Systemic host immune response biomarkers measured at follow-up time point. Table S8. Sensitivity analyses of the association between glucocorticoid use and systemic host immune response biomarkers at follow-up. Table S9. Clinical characteristics by host response subphenotype at baseline. Table S10. Clinical characteristics by host response subphenotype and receipt of glucocorticoids. Table S11. Sensitivity analyses of the association between glucocorticoid use and systemic host immune response biomarkers at follow-up in the hypoinflammatory phenotype subgroup. Table S12. Sensitivity analyses of the association between glucocorticoid use and systemic host immune response biomarkers at follow-up in the hyperinflammatory phenotype subgroup. Figure S1. Kaplan–Meier curves for 90-day survival and liberation from mechanical ventilation. Survival curves are adjusted for propensity score. Adjusted hazard ratio for survival (HR 0.96 [95% CI 0.46–2.01], p = 0.908) and time to liberation (HR 1.03 [95% CI 0.68–1.54, p = 0.905]) did not suggest differences between groups. Hazard ratio generated from Cox proportional hazard modeling with robust regression and proportional hazards assumption tested and not violated in both cases.
Monolithic PDMS Laminates for Dielectric Elastomer Transducers through Open-Air Plasma Treatment
Creators: name: Hassouneh, Suzan Sager
name: Oubæk, Jakob
name: Daugaard, Anders Egede
name: Skov, Anne Ladegaard
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: This study investigates the use of an open-air plasma treatment system for the surface modification of polydimethylsiloxane, to improve layer-to-layer adhesion. The procedure presented herein is more cost-efficient compared to conventional vacuum-based plasma treatment, and it is performed at different speeds and distances away from the nozzle, to investigate how these two parameters influence the resulting interfacial layer of two fully cured polydimethylsiloxane films. The plasma treatment is determined to not alter mechanical properties as compared to the single film, while peel forces are sufficient to avoid delamination during operation.
Conformational, vibrational spectroscopic, nonlinear optical activity, and structure–activity studies on 2-hydroxy-3,5-dinitropyridine: Combined experimental and density functional theory approach
Creators: name: R. Mohamed Asath
name: T. N. Rekha
name: Rajkumar, Beulah J. M.
name: S. Premkumar
name: A. Jawahar
name: T. Mathavan
name: A. Milton Franklin Benial
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The conformational analysis was carried out to predict the most stable, optimized structure of 2-hydroxy-3,5-dinitropyridine among various conformers. The most stable, optimized structure of the molecule was predicted by the density functional theory (DFT) using the B3LYP method with the cc-pVQZ basis set. The vibrational frequencies, natural atomic charge distribution, and thermodynamic properties were calculated. The molecular electrostatic potential surface and contour map were simulated. The experimental and theoretical vibrational frequencies were assigned on the basis of potential energy distribution calculation. The density of states (DOS) spectrum was simulated. The frontier molecular orbital analysis was carried out. The natural bond orbital (NBO) analysis was performed to evaluate the donor–acceptor interactions in the molecule. The structure–activity descriptors were determined by Fukui functions and local reactivity descriptor calculations. The nonlinear optical (NLO) activity of the molecule was studied. The second harmonic generation test confirms the NLO activity of the title molecule.
Stat3 is a candidate epigenetic biomarker of perinatal Bisphenol A exposure associated with murine hepatic tumors with implications for human health
Creators: name: Weinhouse, Caren
name: Bergin, Ingrid L.
name: Harris, Craig
name: Dolinoy, Dana C.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 60506 Virology

description: Bisphenol A (BPA) is an endocrine disrupting chemical (EDC) that has been implicated as a potential carcinogen and epigenotoxicant. We have previously reported dose-dependent incidence of hepatic tumors in 10-month-old isogenic mice perinatally exposed to BPA. Here, we evaluated DNA methylation at 3 candidate genes (Esr1, Il-6st, and Stat3) in liver tissue of BPA-exposed mice euthanized at 2 time points: post-natal day 22 (PND22; n = 147) or 10-months of age (n = 78, including n = 18 with hepatic tumors). Additionally, DNA methylation profiles were analyzed at human homologs of murine candidate genes in human fetal liver samples (n = 50) with known liver tissue BPA levels. Candidate genes were chosen based on reported expression changes in both rodent and human hepatocellular carcinoma (HCC). Regions for bisulfite sequencing were chosen by mining whole genome next generation sequencing methylation datasets of both mice and human liver samples with known perinatal BPA exposures. One of 3 candidate genes, Stat3, displayed dose-dependent DNA methylation changes in both 10-month mice with liver tumors as compared to those without liver tumors and 3-week sibling mice from the same exposure study, implicating Stat3 as a potential epigenetic biomarker of both early life BPA exposure and adult disease in mice. DNA methylation profiles within STAT3 varied with liver tissue BPA level in human fetal liver samples as well, suggesting STAT3 may be a translationally relevant candidate biomarker. These data implicate Stat3 as a potential early life biomarker of adult murine liver tumor risk following early BPA exposure with early evidence of relevance to human health.
Stat3 is a candidate epigenetic biomarker of perinatal Bisphenol A exposure associated with murine hepatic tumors with implications for human health
Creators: name: Weinhouse, Caren
name: Bergin, Ingrid L.
name: Harris, Craig
name: Dolinoy, Dana C.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 60506 Virology

description: Bisphenol A (BPA) is an endocrine disrupting chemical (EDC) that has been implicated as a potential carcinogen and epigenotoxicant. We have previously reported dose-dependent incidence of hepatic tumors in 10-month-old isogenic mice perinatally exposed to BPA. Here, we evaluated DNA methylation at 3 candidate genes (Esr1, Il-6st, and Stat3) in liver tissue of BPA-exposed mice euthanized at 2 time points: post-natal day 22 (PND22; n = 147) or 10-months of age (n = 78, including n = 18 with hepatic tumors). Additionally, DNA methylation profiles were analyzed at human homologs of murine candidate genes in human fetal liver samples (n = 50) with known liver tissue BPA levels. Candidate genes were chosen based on reported expression changes in both rodent and human hepatocellular carcinoma (HCC). Regions for bisulfite sequencing were chosen by mining whole genome next generation sequencing methylation datasets of both mice and human liver samples with known perinatal BPA exposures. One of 3 candidate genes, Stat3, displayed dose-dependent DNA methylation changes in both 10-month mice with liver tumors as compared to those without liver tumors and 3-week sibling mice from the same exposure study, implicating Stat3 as a potential epigenetic biomarker of both early life BPA exposure and adult disease in mice. DNA methylation profiles within STAT3 varied with liver tissue BPA level in human fetal liver samples as well, suggesting STAT3 may be a translationally relevant candidate biomarker. These data implicate Stat3 as a potential early life biomarker of adult murine liver tumor risk following early BPA exposure with early evidence of relevance to human health.
Stat3 is a Candidate Epigenetic Biomarker of Perinatal Bisphenol A Exposure Associated with Murine Hepatic Tumors with Implications for Human Health
Creators: name: Bergin, Ingrid L.
name: Dolinoy, Dana C.
name: Weinhouse, Caren
name: Harris, Craig
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Molecular Biology
subject: Genetics
subject: Medicine
subject: Biochemistry

description: Bisphenol A (BPA) is an endocrine disrupting chemical (EDC) that has been implicated as a potential carcinogen and epigenotoxicant. We have previously reported dose-dependent incidence of hepatic tumors in 10-month-old isogenic mice perinatally exposed to BPA. Here, we evaluated DNA methylation at three candidate genes (Esr1, Il-6st, and Stat3) in liver tissue of BPA-exposed mice euthanized at two time points: post-natal day 22 (PND22; n=147) or 10-months of age (n=78, including n=18 with hepatic tumors). Additionally, DNA methylation profiles were analyzed at human homologs of murine candidate genes in human fetal liver samples (n=50) with known liver tissue BPA levels. Candidate genes were chosen based on reported expression changes in both rodent and human hepatocellular carcinoma (HCC). Regions for bisulfite sequencing were chosen by mining whole genome next generation sequencing methylation datasets of both mice and human liver samples with known perinatal BPA exposures. One of three candidate genes, Stat3, displayed dose-dependent DNA methylation changes in both 10-month mice with liver tumors as compared to those without liver tumors and 3-week sibling mice from the same exposure study, implicating Stat3 as a potential epigenetic biomarker of both early life BPA exposure and adult disease in mice. DNA methylation profiles within STAT3 varied with liver tissue BPA level in human fetal liver samples as well, suggesting STAT3 may be a translationally relevant candidate biomarker. These data implicate Stat3 as a potential early life biomarker of adult murine liver tumor risk following early BPA exposure with early evidence of relevance to human health.
Estimation of genetic parameters related to eggshell strength using random regression models
Creators: name: J. Guo
name: M. Ma
name: L. Qu
name: M. Shen
name: T. Dou
name: K. Wang
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: Genetics

description: 1. This study examined the changes in eggshell strength and the genetic parameters related to this trait throughout a hen’s laying life using random regression.2. The data were collected from a crossbred population between 2011 and 2014, where the eggshell strength was determined repeatedly for 2260 hens.3. Using random regression models (RRM), several Legendre polynomials were employed to estimate the fixed, direct genetic and permanent environment effects. The residual effects were treated as independently distributed with heterogeneous variance for each test week.4. The direct genetic variance was included with second order Legendre polynomials and the permanent environment with third order Legendre polynomials.5 The heritability of eggshell strength ranged from 0.26 to 0.43, the repeatability ranged between 0.47 and 0.69, and the estimated genetic correlations between test weeks was high at > 0.67.6. The first eigenvalue of the genetic covariance matrix accounted for about 97% of the sum of all the eigenvalues.7. The flexibility and statistical power of RRM suggest that this model could be an effective method to improve eggshell quality and to reduce losses due to cracked eggs in a breeding plan.
Symmetry-induced higher-order exceptional points in two dimensions
Creators: name: Montag, Anton
name: Kunst, Flore K.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Exceptional points of order $n$ (EP$n$s) appear in non-Hermitian systems as points where the eigenvalues and eigenvectors coalesce. They emerge if $2(n-1)$ real constraints are imposed, such that EP2s generically appear in two dimensions (2D). Local symmetries have been shown to reduce this number of constraints. In this work, we provide a complete characterization of the appearance of symmetry-induced higher-order EPs in 2D parameter space. We find that besides EP2s only EP3s, EP4s, and EP5s can be stabilized in 2D. Moreover, these higher-order EPs must always appear in pairs with their dispersion determined by the symmetries. Upon studying the complex spectral structure around these EPs, we find that depending on the symmetry, EP3s are accompanied by EP2 arcs, and two- and three-level open Fermi structures. Similarly, EP4s and closely related EP5s, which arise due to multiple symmetries, are accompanied by exotic EP arcs and open Fermi structures. For each case, we provide an explicit example. We also comment on the topological charge of these EPs, and discuss similarities and differences between symmetry-protected higher-order EPs and EP2s.
Additional file 1 of Identification of biomarkers and pathways for the SARS-CoV-2 infections in obstructive sleep apnea patients based on machine learning and proteomic analysis
Creators: name: Luo, Hong
name: Yan, Jisong
name: Gong, Rui
name: Zhang, Dingyu
name: Zhou, Xia
name: Wang, Xianguang
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Computational Biology

description: Supplementary 1.
On pole-skipping with gauge-invariant variables in holographic axion theories
Creators: name: Ahn, Yongjun
name: Jahnke, Viktor
name: Jeong, Hyun-Sik
name: Ji, Chang-Woo
name: Kim, Keun-Young
name: Nishida, Mitsuhiro
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the pole-skipping phenomenon within holographic axion theories, a common framework for studying strongly coupled systems with chemical potential ($μ$) and momentum relaxation ($β$). Considering the backreaction characterized by $μ$ and $β$, we encounter coupled equations of motion for the metric, gauge, and axion field, which are classified into spin-0, spin-1, and spin-2 channels. Employing gauge-invariant variables, we systematically address these equations and explore pole-skipping points within each sector using the near-horizon method. Our analysis reveals two classes of pole-skipping points: regular and singular pole-skipping points in which the latter is identified when standard linear differential equations exhibit singularity. Notably, pole-skipping points in the lower-half plane are regular, while those elsewhere are singular. This suggests that the pole-skipping point in the spin-0 channel, associated with quantum chaos, corresponds to a singular pole-skipping point. Additionally, we observe that the pole-skipping momentum, if purely real or imaginary for $μ=β=0$, retains this characteristic for $μ\neq0$ and $β\neq 0$.
description: 30 pages, 3 figures
Engagement of Learning Video Game Music Composition Techniques in VR
Creators: name: Sheng, Wesley Essex
Publisher: name: Purdue University Graduate School
Year: 2025
Subjects: classificationCode: 460702
subject: Computer graphics
classificationCode: 460708
subject: Virtual and mixed reality
classificationCode: 460707
subject: Sound and music computing

description: Although interest in applying education to virtual reality applications continues to grow, there is a lack of research in specialized fields such as composing video game music. This lends itself to a gap in the effectiveness of such contexts. In addition, research surrounding the topic of measuring engagement of learning music in virtual reality is insufficient, leading to a lack of clarity on whether users of virtual reality technology are motivated for continuous learning. This study developed and evaluated a virtual reality sandbox environment to teach composing video game music. Results revealed an average SUS score of 74.250, indicating good usability. Additional results revealed PENS scores of 5.228 for competence, 5.298 for autonomy, and 4.122 for relatedness, indicating that the environment engaged participants in learning video game music composition; the lower relatedness score reflects a need for features such as sharing. Within a modified MLM framework, identification and integration scores averaged 3.125 with a standard deviation of 1.486, indicating that the participants’ learning experiences varied. Nonetheless, intrinsic motivation was consistently high, was an average value of 5.236. While the findings showcase the potential of VR environments for learning to compose video game music, future improvements in application features and study design could improve user experiences and motivational outcomes.
Reconstitution of biosynthetic machinery of fungal polyketides: unexpected oxidations of biosynthetic intermediates by expression host
Creators: name: Ryuya Fujii
name: Ugai, Takahiro
name: Ichinose, Hirofumi
name: Hatakeyama, Mayumi
name: Kosaki, Takuto
name: Gomi, Katsuya
name: Fujii, Isao
name: Minami, Atsushi
name: Oikawa, Hideaki
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Reconstitution of whole biosynthetic genes in Aspergillus oryzae has successfully applied for total biosynthesis of various fungal natural products. Heterologous production of fungal metabolites sometimes suffers unexpected side reactions by host enzymes. In the studies on fungal polyketides solanapyrone and cytochalasin, unexpected oxidations of terminal olefin of biosynthetic intermediates were found to give one and four by-products by host enzymes of the transformants harboring biosynthetic genes. In this paper, we reported structure determination of by-products and described a simple solution to avoid the undesired reaction by introducing the downstream gene in the heterologous production of solanapyrone C. Heterologous production in Aspergillus oryzae.
Heartwood extract of Rhus verniciflua Stokes and its active constituent fisetin attenuate vasoconstriction through calcium-dependent mechanism in rat aorta
Creators: name: Park, Jung-Min
name: Jun-Hyeong Lee
name: Chun-Soo Na
name: Dongho Lee
name: Lee, Jin-Yong
name: Satoh, Masahiko
name: Moo-Yeol Lee
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Hematology

description: Rhus verniciflua Stokes (RVS) exert cardiovascular protective activity by promoting blood circulation, but its active ingredients and underlying mechanism have yet to be identified. This study investigated the vascular effects of RVS, focusing on vasoconstriction and smooth muscle Ca2+ signaling. RVS heartwood extract attenuated contraction of aortic rings induced by the vasoconstrictors serotonin and phenylephrine, and inhibited the Ca2+ signaling evoked by serotonin in vascular smooth muscle cells. Subsequent activity-guided fractionation identified fisetin as an active constituent exerting a Ca2+ inhibitory effect. Fisetin could inhibit major Ca2+ mobilization pathways including extracellular Ca2+ influx mediated by the L-type voltage-gated Ca2+ channel, Ca2+ release from the intracellular store and store-operated Ca2+ entry. In accordance with Ca2+ inhibitory effect, fisetin attenuated vasoconstriction by serotonin and phenylephrine. These results suggest that the anticontractile effect, which is presumably mediated by inhibition of Ca2+ signaling, may contribute to the improvement of blood circulation by RVS. Rhus verniciflua Stokes extract and its active constituent fisetin improve blood circulation by inhibiting smooth muscle Ca2+ signaling and thereby attenuating vasoconstriction.
Reconstitution of biosynthetic machinery of fungal polyketides: unexpected oxidations of biosynthetic intermediates by expression host
Creators: name: Ryuya Fujii
name: Ugai, Takahiro
name: Ichinose, Hirofumi
name: Hatakeyama, Mayumi
name: Kosaki, Takuto
name: Gomi, Katsuya
name: Fujii, Isao
name: Minami, Atsushi
name: Oikawa, Hideaki
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Reconstitution of whole biosynthetic genes in Aspergillus oryzae has successfully applied for total biosynthesis of various fungal natural products. Heterologous production of fungal metabolites sometimes suffers unexpected side reactions by host enzymes. In the studies on fungal polyketides solanapyrone and cytochalasin, unexpected oxidations of terminal olefin of biosynthetic intermediates were found to give one and four by-products by host enzymes of the transformants harboring biosynthetic genes. In this paper, we reported structure determination of by-products and described a simple solution to avoid the undesired reaction by introducing the downstream gene in the heterologous production of solanapyrone C. Heterologous production in Aspergillus oryzae.
Additional file 1 of Association between serum triglycerides and stroke type, severity, and prognosis. Analysis in 6558 patients
Creators: name: Akhtar, Naveed
name: Singh, Rajvir
name: Kamran, Saadat
name: Joseph, Sujatha
name: Morgan, Deborah
name: Uy, Ryan Ty
name: Treit, Sarah
name: Shuaib, Ashfaq
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biological Sciences not elsewhere classified

description: Supplementary Material 1.
Monolithic PDMS Laminates for Dielectric Elastomer Transducers through Open-Air Plasma Treatment
Creators: name: Hassouneh, Suzan Sager
name: Oubæk, Jakob
name: Daugaard, Anders Egede
name: Skov, Anne Ladegaard
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: This study investigates the use of an open-air plasma treatment system for the surface modification of polydimethylsiloxane, to improve layer-to-layer adhesion. The procedure presented herein is more cost-efficient compared to conventional vacuum-based plasma treatment, and it is performed at different speeds and distances away from the nozzle, to investigate how these two parameters influence the resulting interfacial layer of two fully cured polydimethylsiloxane films. The plasma treatment is determined to not alter mechanical properties as compared to the single film, while peel forces are sufficient to avoid delamination during operation.
Heartwood extract of Rhus verniciflua Stokes and its active constituent fisetin attenuate vasoconstriction through calcium-dependent mechanism in rat aorta
Creators: name: Park, Jung-Min
name: Jun-Hyeong Lee
name: Chun-Soo Na
name: Dongho Lee
name: Lee, Jin-Yong
name: Satoh, Masahiko
name: Moo-Yeol Lee
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Hematology

description: Rhus verniciflua Stokes (RVS) exert cardiovascular protective activity by promoting blood circulation, but its active ingredients and underlying mechanism have yet to be identified. This study investigated the vascular effects of RVS, focusing on vasoconstriction and smooth muscle Ca2+ signaling. RVS heartwood extract attenuated contraction of aortic rings induced by the vasoconstrictors serotonin and phenylephrine, and inhibited the Ca2+ signaling evoked by serotonin in vascular smooth muscle cells. Subsequent activity-guided fractionation identified fisetin as an active constituent exerting a Ca2+ inhibitory effect. Fisetin could inhibit major Ca2+ mobilization pathways including extracellular Ca2+ influx mediated by the L-type voltage-gated Ca2+ channel, Ca2+ release from the intracellular store and store-operated Ca2+ entry. In accordance with Ca2+ inhibitory effect, fisetin attenuated vasoconstriction by serotonin and phenylephrine. These results suggest that the anticontractile effect, which is presumably mediated by inhibition of Ca2+ signaling, may contribute to the improvement of blood circulation by RVS. Rhus verniciflua Stokes extract and its active constituent fisetin improve blood circulation by inhibiting smooth muscle Ca2+ signaling and thereby attenuating vasoconstriction.
Conformational, Vibrational Spectroscopic, Nonlinear Optical Activity and Structure-Activity Studies on 2-hydroxy-3,5-dinitropyridine: Combined Experimental and Density Functional Theory Approach
Creators: name: R, Mohamed Asath
name: N, Rekha T
name: Rajkumar, Beulah J.M.
name: S, Premkumar
name: A. Jawahar
name: Mathavan T
name: Benial, Milton Franklin
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Biological Sciences
Chemistry
Biotechnology
Cell Biology
Physics
Biochemistry
Biophysics

description: The conformational analysis was carried out to predict the most stable, optimized structure of the 2-hydroxy-3,5-dinitropyridine among various conformers. The most stable, optimized structure of the molecule was predicted by the density functional theory using the B3LYP method with cc-pVQZ basis set. The vibrational frequencies, natural atomic charge distribution and thermodynamic properties were calculated. The molecular electrostatic potential surface and contour map were simulated. The experimental and theoretical vibrational frequencies were assigned on the basis of potential energy distribution calculation. The density of states spectrum was simulated. The frontier molecular orbitals analysis was carried out. The natural bond orbital analysis was performed to evaluate the donor-acceptor interactions in the molecule. The structure-activity descriptors were determined by Fukui functions and local reactivity descriptors calculations. The nonlinear optical activity of the molecule was studied. The second harmonic generation test confirms the nonlinear optical activity of the title molecule.
Tutorial on laser locking techniques and the manufacturing of vapor cells for spectroscopy
Creators: name: Mäusezahl, Max
name: Munkes, Fabian
name: Löw, Robert
Publisher: name: arXiv
Year: 2024
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: This tutorial provides a hands-on entry point about laser locking for atomic vapor research and related research such as laser cooling. We furthermore introduce common materials and methods for the fabrication of vapor cells as a tool for this research. Its aim is not to be exhaustive, but rather to provide an overview about the possible techniques that are actively employed in labs today. Some critical parameters of locked laser system for use with thermal atomic vapors are introduced and discussed. To exemplify this, we describe a versatile locking system that caters for many of the needs we found during our research with thermal atomic vapors. We also emphasize the compromises we took during our decision-making process.
description: 58 pages, 14 figures
title: Characterising surface water groundwater interaction using airborne electromagnetics: a case study from the Cooper Creek floodplain, Queensland, Australia, workflow release
Creators: name: N., Symington
name: N., Symington
name: T., Evans
name: A., McPherson
name: S., Buckerfield
name: N., Rollet
name: A., Ray
name: L Halas
Publisher: name: Commonwealth of Australia (Geoscience Australia)
Year: 2024
Subjects: subject: EFTF – Exploring for the Future
subject: National Groundwater Systems
subject: groundwater
subject: airborne electromagnetics
subject: jupyter notebook
subject: recharge
subject: discharge
subject: Groundwater hydrology
subject: Published_External

description: As part of the Exploring for the Future (EFTF) programme, the groundwater team undertook an in-depth investigation into characterising surface water -- groundwater interaction in the Cooper Creek floodplain using airborne electromagnetics (AEM). This work is to be released as part of the Lake Eyre Basin detailed inventory and as an EFTF extended abstract. As part of Geoscience Australia's commitment to transparent science, the scientific workflows that underpinned a large component of this investigation are to be released as a jupyter notebook. This notebook contains python code, figures and explanatory text that the reader can use to understand how the AEM data were processed, visualised, integrated with other data and interpreted.
Monolithic PDMS Laminates for Dielectric Elastomer Transducers through Open-Air PlasmA-Treatment
Creators: name: Hassouneh, Suzan Sager
name: Oubæk, Jakob
name: Daugaard, Anders Egede
name: Skov, Anne Ladegaard
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Medicine
subject: Physics
subject: Engineering
subject: Biophysics

description: ABSTRACTThe present study investigates the use of an open-air plasma-treatment system for the surface modification of polydimethylsiloxane (PDMS), in order to improve layer-to-layer adhesion. The procedure presented herein is more cost efficient compared to conventional vacuum-based plasma-treatment, and it is performed at different speeds and distances away from the nozzle, to investigate how these two parameters influence the resulting interfacial layer of two fully cured PDMS films. The plasma-treatment is determined not to alter mechanical properties compared to the single film, while peel forces are sufficient to avoid delamination during operation.
Additional file 1 of Translucency of recent zirconia materials and material-related variables affecting their translucency: a systematic review and meta-analysis
Creators: name: Yousry, Mahinour
name: Hammad, Ihab
name: Halawani, Mohamed El
name: Aboushelib, Moustafa
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Supplementary Materials 1.
Revisiting thermodynamics in (LiF, NaF, KF, CrF2)-CrF3 by first-principles calculations and CALPHAD modeling
Creators: name: Gong, Rushi
name: Shang, Shun-Li
name: Wang, Yi
name: Palma, Jorge Paz Soldan
name: Kim, Hojong
name: Liu, Zi-Kui
Publisher: name: arXiv
Year: 2024
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The thermodynamic description of the (LiF, NaF, KF, CrF2)-CrF3 systems has been revisited, aiming for a better understanding of the effects of Cr on the FLiNaK molten salt. First-principles calculations based on density functional theory (DFT) were performed to determine the electronic and structural properties of each compound, including the formation enthalpy, volume, and bulk modulus. DFT-based phonon calculations were carried out to determine the thermodynamic properties of compounds, for example, enthalpy, entropy, and heat capacity as functions of temperature. Phonon-based thermodynamic properties show a good agreement with experimental data of binary compounds LiF, NaF, KF, CrF3, and CrF2, establishing a solid foundation to determine thermodynamic properties of ternary compounds as well as to verify results estimated by the Neumann-Kopp rule. Additionally, DFT-based ab initio molecular dynamics (AIMD) simulations were employed to predict the mixing enthalpies of liquid salts. Using DFT-based results and experimental data in the literature, the (LiF, NaF, KF, CrF2)-CrF3 system has been remodeled in terms of the CALculation of PHAse Diagrams (CALPHAD) approach using the modified quasichemical model with quadruplet approximation (MQMQA) for liquid. Calculated phase stability in the present work shows an excellent agreement with experiments, indicating the effectiveness of combining DFT-based total energy, phonon, and AIMD calculations, and CALPHAD modeling to provide the thermodynamic description in complex molten salt systems.
Propuesta de mejora del proceso de despacho en una empresa que produce y comercializa acero dimensionado
Creators: name: Repositorio Academico UPC
name: Barrionuevo Castillo, Juan Karlo
Publisher: name: figshare
Year: 2015
Subjects: Uncategorized

description: El presente trabajo tuvo como finalidad presentar propuestas para mejorar el proceso de despacho en una empresa que produce y comercializa acero dimensionado, mediante el análisis cuantitativo de los principales problemas en las actividades logísticas. Para identificar las oportunidades de mejora se tuvo que elaborar un diagnóstico del proceso actual de despacho y se analizó las estadísticas de las principales etapas de dicho proceso, con ello se pudo identificar las desviaciones de los indicadores clave y, en base a estos resultados, se decidió trabajar en dichas etapas. El trabajo está compuesto de cuatro capítulos. En el primero se define el marco teórico de la investigación. En el segundo capítulo se elabora el diagnóstico del proceso actual de despacho y se identifican los principales problemas de este. En el tercero se desarrollan las propuestas de mejora. Finalmente, se presentan las conclusiones y recomendaciones del trabajo. De este modo, se puede puede determinar que con la implementación de un sistema de control en el reaprovisionamiento de producto terminado, la estandarización de los procesos, la redistribución del almacén y una mayor planificación de la programación y distribución, se puede lograr el cometido de la tesis.
Additional file 1 of Novel surgical approaches for treating myopic traction maculopathy: a meta-analysis
Creators: name: Quiroz-Reyes, Miguel A.
name: Quiroz-Gonzalez, Erick A.
name: Quiroz-Gonzalez, Miguel A.
name: Lima-Gomez, Virgilio
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 1.