cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supporting Parents of Young Children in the Child Welfare System
Creators: name: Beckmann, Katherine Anne
name: Knitzer, Jane
name: Cooper, Janice L.
name: Dicker, Sheryl
Publisher: name: Columbia University
Year: 2010
Subjects: Child welfare
Child welfare--Government policy
Child welfare--Evaluation
Parents--Services for

description: Consistent, responsive, and nurturing early relationships foster emotional well-being in young children, as well as create the foundation for the behavioral, social, and cognitive development essential for school readiness. Developmental research tells us that parents are one of the most important influences on children with high quality parenting essential for healthy child development. Thus, preventing behavior problems in young children requires family-oriented, evidence-informed strategies that address the needs of both parents and their children. This report explores the challenges and opportunities of improving mandated parent training for parents of young children in the child welfare system. Drawing on lessons from research and practice, it calls on states, courts and communities to use more intentional, cost effective, and strategic approaches to required parent training. The report is based on Improving Parenting Outcomes for Children in the Child Welfare System: an emerging issues roundtable that the National Center for Children in Poverty conducted in July 2007 in New York. The forum brought together leaders in child welfare, policymakers, philanthropists, researchers and those with practice expertise to explore the best means to ensure effective parenting training and to consider action steps to help this high risk population. (See Appendix I for a list of participants.) While parent education is only one component of a comprehensive service plan to help parents better parent, it is a point of potential leverage to improve the child welfare system by providing more effective prevention services, such as parenting education, and spending scarce resources more efficiently. This report explores the research, proposes criteria for effective programs, and discusses strategies that can be used at the local, state and national levels to change policy and practice.
Theory of STM junctions for π-conjugated molecules on thin insulating films
Creators: name: Sobczyk, Sandra
name: Donarini, Andrea
name: Grifoni, Milena
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A microscopic theory of the transport in a scanning tunnelling microscope (STM) set-up is introduced for π-conjugated molecules on insulating films, based on the density matrix formalism. A key role is played in the theory by the energy dependent tunnelling rates which account for the coupling of the molecule to the tip and to the substrate. In particular, we analyze how the geometrical differences between the localized tip and extended substrate are encoded in the tunnelling rate and influence the transport characteristics. Finally, using benzene as an example of a planar, rotationally symmetric molecule, we calculate the STM current voltage characteristics and current maps and analyze them in terms of few relevant angular momentum channels.
description: 19 pages, 12 figures, minor changes to conform to published version
Star formation and molecular gas observations of NGC 5331 with ALMA and VLA
Creators: name: Kunneriath, Devaky
name: Barcos-Munoz, Loreto
name: Saravia, Alejandro
name: Rodas-Quito, Eduardo
Publisher: name: Zenodo
Year: 2023

description: LIRGs (Luminous Infra-Red Galaxies) make up the brightest objects in the infrared sky and represent an important population to study galaxy evolution. Models predict episodic enhancements of the total star formation of the system as the merger progresses. We know the molecular gas is the fuel for star formation, which explains the empirical correlation seen between the star formation rate and molecular gas surface densities in galaxies, described by the Kennicutt-Schmidt relation: Σ_SFR = Σ_mol., where N∼1.4 (Schmidt 1959, Kennicutt 1998). Most studies of this relation have been done using integrated measurements (Kennicutt 1998, Kennicutt & De Los Reyes 2021), however recent works at sub-kpc scales have found a wide range of values for N (e.g., Leroy et al. 2008, Pereira-Santaella et al. 2016). In this work, we study the K-S relation at 1.2 kpc scales in the nearby LIRG, NGC 5331. We use VLA radio continuum observations (3 GHz) to trace unobscured SF, as opposed to UV and/or Halpha, which suffer greatly from dust obscuration, especially in U/LIRGs, and ALMA CO (1-0) line emission observations to derive the molecular gas properties of this local LIRG.
Probing 3-3-1 Models in Diphoton Higgs Boson Decay
Creators: name: Alves, A.
name: Barreto, E. Ramirez
name: Dias, A. G.
name: Pires, C. A. de S.
name: Queiroz, F. S.
name: da Silva, P. S. Rodrigues
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the Higgs boson production through gluon fusion and its decay into two photons at the LHC in the context of the minimal 3-3-1 model and its alternative version with exotic leptons. The diphoton Higgs decay channel presents an enhanced signal in this model compared to the Standard Model due to the presence of an extra singly charged vector boson and a doubly charged one. Prospects for the Higgs boson detection at 7 TeV center-of-mass energy with up to 10 fb$^{-1}$ are presented. Our results suggest that a Higgs boson from these 3-3-1 models can potentially explain the small excess for $m_H\leq 145$ GeV observed at the LHC. Otherwise, if this excess reveals to be only a statistical fluctuation of the Standard Model backgrounds severe constraints can be put on these models.
description: Corrections in the text done, 24 pages, 5 figures
Unclaimed Children Revisited: Focusing on Outcomes—A Case Study of the Michigan Level of Functioning Project
Creators: name: Banghart, Patti L.
name: Cooper, Janice L.
Publisher: name: Columbia University
Year: 2010
Subjects: Child mental health
Child mental health services
Teenagers--Mental health
Teenagers--Services for
Mental health policy

description: The major aim of Unclaimed Children Revisited is to identify policy-supported state efforts to promote quality of care for children and youth with mental health conditions in the public mental health system. The Michigan Case Study examines one such initiative - Michigan’s Level of Functioning Project (LOF). It is a 14 year-old effort to monitor and improve outcomes for children and youth with severe emotional disturbance (SED), through the use of the Child and Adolescent Functional Assessment Scale (CAFAS), a research-based tool that measures children’s daily functioning. The LOF aims to gather data on outcomes for children and youth with SED served through Michigan’s public mental health system. This data can then be used to inform decision-making at the policy and service delivery levels.
Preparedness to prevent Desert Locust plagues in the Central Region: an historical review: Part 1. Text
Creators: name: Magor, J. I.
name: Ceccato, Pietro N.
name: Dobson, H. M.
name: Pender, J.
name: Ritchie, L.
Publisher: name: Columbia University
Year: 2007
Subjects: Environmental sciences

description: This review provides background information for discussing Desert Locust control strategies and tactics. The illustrated text describes the evolution of the control strategy from 1930 onwards, the spatial and temporal characteristics of outbreaks, upsurges and plagues and methods of assessing the threat this locust poses to agriculture in Africa, the Near East and southwest Asia. An early warning system has operated since the 1940s as part of the collaborative national, regional and international system to prevent Desert Locust plagues. Methods of assessing plague prevention preparedness are described as are factors currently limiting the sustainability of the system.
New Ethical Leadership: Marianne Williamson 1
Creators: name: Fisher, R. M.
Publisher: name: In Search of Fearlessness Research Institute
Year: 2019
Subjects: fearology
political leadership
ethical leadership

description: This video by Dr. R. M. Fisher, current founder and director of The Fearology Institute, covers his fearological perspective on the new paradigm of ethical leadership towards fearless leadership by various great political leaders, the focus particularly on Marianne Williamson who has just announced her campaign to run for president of the USA in 2020. This is part of the Fearlessness Movement, since the beginning of human history, according to Fisher and we best give this a lot of study and attention and explore how to make it a successful teaching for all. Fisher offers his own approach and philosophy to the campaign and calls for a united front to help all people move from fear-based living to fearlessness, from a culture of coping and fear to a healing culture of fearlessness. He says it is very important to support the feminine, feminist, womanist leaders, like Marianne Williamson. He critiques briefly the labeling of "sociopathic" as used by Williamson and others for the 'enemy' and says we need a lot more questioning about that strategy and its usefulness-- such labeling is typical of a fear-based perspective itself. We need a fearlessness-based way of thinking through this problem, like all other difficult problems in society. Fisher, is planning a Part 2 video soon... ABC News just did a feature on MW's campaign well worth watching: https://abcnews.go.com/Nightline/vide...
Qualitätsstandards für forschungsdaten.info
Creators: name: Redaktion von forschungsdaten.info
Publisher: name: Zenodo
Year: 2024
Subjects: Qualität
forschungsdaten.info
Redaktion
Qualitätsstandards
Quellen
Review

description: Im Rahmen der Landesinitiative bwFDM hat sich die Redaktion von forschungsdaten.info ein Set an Qualitätsstandards gegeben. Diese werden Stück für Stück in die redaktionelle Arbeit überführt.
Counsellor empathy or “having a heart to help”? : an ethnographic investigation of Chinese clients’ experience of counselling
Creators: name: Ng, Chi Ting Connie
Publisher: name: University of British Columbia
Year: 2011

description: Multicultural education has become an integral part of professional training in counselling psychology. Empathy refers to one’s ability to hear, to feel, and to acknowledge others’ experiences, and has been regarded as an essential counsellor skill in psychotherapy. However, current understanding of empathy is almost entirely based on Western culture and may not match with non-Western clients’ expectations in cross-cultural counselling. As well, research regarding counsellor empathy in cross-cultural counselling has often focused on counsellors’ self-reports, and clients’ perceptions of empathy are scarcely investigated within any cultural group. The present qualitative research, namely, ethnographic interview, examined the concept of counsellor empathy from Chinese clients’ perspectives by exploring their experiences of therapeutic relationships. Eight informants, two male and six female, ranging in age from 40 to 55, were interviewed in-depth about their experiences of seeing Chinese counsellors. Elements of counsellor empathy were examined with the interview data obtained. Nine themes emerged from data analysis. They are: (a) Counsellor Professionalism, (b) Counsellor Attitudes, (c) Empathy, (d) Counsellor Disclosure, (e) Client Confidentiality, (f) The Counselling Process, (g) Chatting, (h) Roles of Clients and Client-Counsellor Relationship in Counselling, and (i) Perceived Importance in Counselling. Based on the results, it is found that the concept of counsellor empathy existed, but not commonly, in informants’ perceptions. Also, it was not considered as a priority in counselling according to informants’ perspectives. It is conjectured that counsellor empathy might exist in Chinese counselling relationships as a different phenomenon linguistically and conceptually. Implication for practice and future research are delineated.
Preparedness to prevent Desert Locust plagues in the Central Region: an historical review: Part 2. Appendices
Creators: name: Magor, J. I.
name: Ceccato, Pietro N.
name: Dobson, H. M.
name: Pender, J.
name: Ritchie, L.
Publisher: name: Columbia University
Year: 2007
Subjects: Environmental sciences

description: This review provides background information for discussing Desert Locust control strategies and tactics. The illustrated text describes the evolution of the control strategy from 1930 onwards, the spatial and temporal characteristics of outbreaks, upsurges and plagues and methods of assessing the threat this locust poses to agriculture in Africa, the Near East and southwest Asia. An early warning system has operated since the 1940s as part of the collaborative national, regional and international system to prevent Desert Locust plagues. Methods of assessing plague prevention preparedness are described as are factors currently limiting the sustainability of the system.
Promoting Language and Literacy in Early Childhood Care and Education Settings
Creators: name: Child Care & Early Education Research Connections
Publisher: name: Columbia University
Year: 2004
Subjects: Children--Language
Literacy
Early childhood education
Language arts (Early childhood)

description: The foundation for life-long literacy is established during the early childhood years. Emergent literacy and language acquisition skills precede the ability to read and write and influence later literacy skills development. Young children who develop an awareness of and interest in literature and language are more likely to enter school with increased early literacy skills and to experience academic success in later years. This brief summarizes Promoting language and literacy in early childhood care and education settings: Literature review (Halle, Calkins, Berry, & Johnson, 2003, see www.childcareresearch.org/location/ccrca2796), a more extensive review of research on programs to promote language and emergent literacy in early childhood care and education settings for children ages three to five. The literature review focused on 'targeted interventions,' that is, programs designed specifically and exclusively to enhance children's language and literacy development, as well as on 'comprehensive interventions,' that is, programs that include a language and early literacy component but aim to improve multiple developmental outcomes by offering additional services (e.g., home visits, parent support groups, pediatric check-ups) sometimes starting in infancy, and usually running for longer periods of time than targeted interventions. Examples of comprehensive interventions are the High/Scope Perry Preschool Study, the Infant Health and Development Program, the Abecedarian Project, the Early Head Start Research and Evaluation Project, and the Chicago Child Parent Center and Expansion Program. The review only selected studies that followed rigorous empirical research designs and were published in peer-reviewed journals. A table summarizing the studies cited in the larger review is located at www.childcareresearch.org/location/ccrca2797.
L. E. T. 2: Process of Balance
Creators: name: Fisher, R. M.
Publisher: name: In Search of Fearlessness Research Institute
Year: 2019
Subjects: Life Enhancement Training
process thinking
restoration of health
growth

description: Dr. Fisher, founder of Life Enhancement Training (L. E. T.) describes in an introductory talk the primary lessons he wants all learners of LET to learn. He describes what Big Life is, and why changing perspectives is crucial to our restoration and health, growth and healing... and what "balance" means as the theme of this session. Process thinking is critical to success in this program and these are the first indications of how to start to shift our attention. Later videos on LET will go into detail of the technologies of caring and processes of healing. The larger goal is to help society shift from a coping culture to a healing culture. For the Introductory video on L. E. T. and an overview of the entire program design (first-aid, second-aid, third-aid) go to: https://www.youtube.com/watch?v=iYX1x... NOTE: There are a few other people on the Internet using L. E. T. as well for their programs and that's just fine with me, the uniqueness of my version is all that is important; and so I do not endorse other L. E. T. labeled programs, nor do they endorse mine. NOTE: My use of "Big Life" and "small life" although a useful metaphor perhaps, ought not be mistaken with the obsessive growth-mania of W. modern civilization that just because something is big or bigger it is better! No, I do not follow that mandate. I could just as easily have used, and will use at times in the training, "Expanded Life" instead of "Big LIfe" .
Participatory governance, sprawl and sustainability in Gatineau, Quebec
Creators: name: Morison, Stephen J.
Publisher: name: University of British Columbia
Year: 2011

description: Rooted in overwhelming evidence that our societies are not sustainable, this thesis explores the potential for participatory governance to improve the sustainability of land-use planning and decision-making. Participation is argued to be a critical component of governance for sustainability, for at least two reasons: (1) that to sustainably manage the incredibly complex interactions between human society and the environment requires profound understanding of those interactions; and (2) that to implement sustainability-oriented policies requires the consent and effort of those people that interacts with the environment. Focusing on urban sprawl as one facet of poor land-use governance for sustainability, this research took the form of a case study of urban sprawl in the City of Gatineau, Quebec, Canada. I explored the processes that facilitate and obstruct the participation of various people, groups and institutions in land-use governance, and analysed the likely impact of this governance structure on land-use sustainability. I employed policy analysis and 22 ethnographic interviews with local citizens, members of civil society groups, journalists, municipal councillors and public servants. I analysed these data within a framework of “goods” of participatory governance, namely: (1) inclusiveness; (2) popular control; (3) considered judgement; (4) transparency; and (5) efficiency. I concluded that land-use governance in Gatineau generally fails to foster meaningful civic participation: residents are not systematically included or represented, and have little control over governance processes; current processes and institutions do not foster considered judgement on land-use issues; while efforts have been made to improve transparency, this is still very lacking; and, what citizen-engagement exists is inefficient, time-intensive and emotionally demanding. I further concluded that: Land-use governance does not systematically ensure that complete and complex information is considered in decision-making; and Current governance processes are not adequate to build or maintain trust, buy-in and perceived legitimacy with citizens. As such, the current approach to land-use governance, and in particular the failure to foster meaningful civic participation, means that land-use governance in Gatineau is unlikely to produce sustainable outcomes. I end with a set of recommendations, for both the City government and civil society in Gatineau.
Economic Value of Climate Variability Impacts on Coconut Production in Sri Lanka
Creators: name: Zubair, Lareef M.
name: Peiris, T. S. G.
name: Ranasinghe, C. S.
name: Ratnasiri, J.
Publisher: name: Columbia University
Year: 2007
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Agriculture

description: This paper assesses the economic value of climate variability, employing a percentile analysis on an array of 31-years national annual coconut production data from 1971 to 2001. Of the production array, 10% and 90% percentiles have been considered respectively as lower and upper production extremes. The 60% of production departures of each year of extremes with respect to the mean production of 10% to 90% percentile were attributed to climate variability because studies show that the 60% of the variation of coconut production is explained by climate. These production deviations were then valued multiplying by free-on-board (FOB) prices of fresh coconuts. Results show that the foregone income from coconuts due to low rainfall varied between US$ 32 million to US$ 73 million while the incremental coconut income in crop glut extremes due to high rainfall varied between US$ 42 million and US$ 87 million. Results show that the climate variability causes income losses to the economy estimated at US$ 32 million to US$ 73 million in years of extreme crop shortage. And in years of extreme crop surplus, the economy realises income gains of US$ 42 million to US$ 87 million. These indicate the potential for significant economic benefits from investments in adaptations that would reduce variability in nut production which is caused by variations in climate. Further work is however needed to estimate the effectiveness and economic benefits that might be achieved from investments in adaptation.
Resonant Repulsion of Kepler Planet Pairs
Creators: name: Lithwick, Yoram
name: Wu, Yanqin
Publisher: name: arXiv
Year: 2012
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Planetary systems discovered by the Kepler space telescope exhibit an intriguing feature. While the period ratios of adjacent low-mass planets appear largely random, there is a significant excess of pairs that lie just wide of resonances and a deficit on the near side. We demonstrate that this feature naturally arises when two near-resonant planets interact in the presence of weak dissipation that damps eccentricities. The two planets repel each other as orbital energy is lost to heat. This moves near-resonant pairs just beyond resonance, by a distance that reflects the integrated dissipation they experienced over their lifetimes. We find that the observed distances may be explained by tides if tidal dissipation is unexpectedly efficient (tidal quality factor ~10). Once the effect of resonant repulsion is accounted for, the initial orbits of these low mass planets show little preference for resonances. This could constrain their origin.
description: minor changes to discussion
Do Canadian nurses differ in their attitudes towards birth?
Creators: name: Liva, Sarah Jane
Publisher: name: University of British Columbia
Year: 2011

description: Background: With a population estimated at 14,192, perinatal nurses are the largest group of Canadian maternity care providers. Knowledge about similarities and differences in nurses’ attitudes towards practice approaches can facilitate strategies to decrease intervention use, and to promote physiologic birth and care providers’ collaboration. Methods: The National Maternity Care Attitudes Study (NMCAS) study surveyed care providers about their attitudes towards birth using a web or paper-based survey. The nursing sample consisted of 545 nurses from across Canada. Using exploratory factor analysis, the NMCAS study revealed nine themes of care provider attitudes, including attitudes towards doulas, electronic fetal monitoring, epidural analgesia, episiotomy, factors that decrease the caesarean section rate, the safety of birth by place or mode (vaginal or caesarean), and the importance of vaginal birth. In this secondary analysis, Chi-Square, ANOVA, Kruskal-Wallis, and multiple regression were used to examine nurses’ demographic group differences in relationship with nurses’ scale scores. Results: Tertiary hospital level of employment predicted more positive attitudes towards epidural analgesia and less positive attitudes towards the importance of vaginal birth. Nurses were significantly more likely to select an obstetrician for their care (adjusted standardized residual, 3.8) if they worked at a tertiary hospital and select a family practitioner if they worked at a level one hospital (adjusted standardized residual, 2.5). Nurses’ selection of an obstetrician for their care predicted less positive attitudes towards the safety of birth, the importance of vaginal birth, and more positive attitudes towards electronic fetal monitoring, episiotomy, and epidural analgesia. Conclusions: Nurses’ attitudes may be influenced by exposures in their workplace and the predominant provider with whom they have contact. Further research is needed to understand relationships between nurses’ attitudes and practice behaviours.
title: Mass transfer resistance of CuCl₂ hydrolysis in a fixed bed reactor
Creators: name: Kankanamalage, Dilum Madushanka Perera
Publisher: name: Memorial University of Newfoundland
Year: 2023

description: The hydrolysis reaction of the Copper-Chlorine (Cu-Cl) cycle is examined in this research to investigate corresponding reaction kinetics with respect to mass transfer resistance through an experimental approach. The experiment was operated at a temperature of 390 °C at atmospheric pressure. The reaction is heterogeneous in which solid reactant CuCl₂ and gaseous reactant H₂O produce Cu₂OCl₂ and HCl. The heterogeneous behaviour of the reaction causes resistance to mass transfer of gaseous reactant H₂O. The resistance in internal diffusion and a surface reaction with mass transfer were analyzed with respect to the initial solid reactant particle size using a shrinking core model (SCM). The results present the thermophysical property of the reaction rate coefficient 0.201 65 s⁻¹ for a particle size of 620 μm and sphericity of 0.68. The experimentally determined reaction and conversion rates of hydrolysis with respect to time are presented, which are experimentally calculated parameters. Scanning Electron Microscopy (SEM) and X-Ray Diffraction (XRD) analysis were used for more accurate results. An uncertainty analysis for the sensors and transducers of the experiment shows that the experimental results have an uncertainty of ±30.1%.
The Great Collapse: How Afraid Should We Be?
Creators: name: Fisher, R. M.
Publisher: name: In Search of Fearlessness Research Institute
Year: 2019
Subjects: cascading global crises
social collapse
environmental collapse
end times

description: Dr. R. Michael Fisher, educator-fearologist, founder and teacher of the School of Sacred Warriorship in the early-to mid-1990s, and many other ventures, talks about the current state of cascading "collapse" of the economic, environmental and social spheres, with implications for the psychic collapse that's also inevitable as extreme conditions of fragility affect everyone, more or less, and sooner or later. He provides several important theories and experiences of how to better understand crises, how to encourage great courage and more importantly fearlessness...and really it is not a very useful question to ask: "How Afraid Should We Be?" Although, that question is a beginning probe into better understanding the path he promotes. This video is a companion to "The Great Citizen" video recently made by Dr. Fisher, so watching both together gives a better balance to his views on the political sphere, and both videos shape a picture of how he is entering politics for the next 10 years (at least)--of which community-building is a core part of his agenda. The Great Citizen: https://www.youtube.com/watch?v=PE7jq... He has lots of experience in community, in diverse communities from the human potential, organic alternative, wellness, therapeutic to liberation communities. He understands the depths of both compassion and wisdom philosophically and through personal experiences. Currently he is teaching his L.E.T. program in the everyday communities of Calgary, AB as a pilot project to engage citizens to take charge of their own lives and the future in a much better way. He proposes in this video on the "Great Collapse" a new type of labor force, to deeply adapt to the challenging and terrifying world we are heading into--coming to face the edge of the cliff. What choices and strategies will we choose?
A new perspective on Gauge-flation
Creators: name: Ghalee, Amir
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Recently Maleknejad and Sheikh-Jabbari have proposed a new model for inflation with non-Abelian gauge fields (Gauge-flation), and they have studied the model by numerical methods\cite{Sheikh}. In this model, the isotropy of space-time is recovered by suitable combination of gauge configurations, and a scalar field is constructed by gauge field and the scale factor, which produces inflation period. In this work, exact solutions for the scalar field and the Hubble parameter are presented and we provide analytic solutions for the numerical results. We explicitly present Hubble parameter and fields as functions of time and it is also demonstrated that in some conditions they are damped oscillator. Moreover, reheating period in the model is discussed.
description: 7 pages, 6 figures,3 figures and a section added, improved discussion
MAO-B inhibitors protect against lipopolysaccharide-mediated epithelial barrier loss and cytokine release
Creators: name: Senini, Vincent Wally James
Publisher: name: University of British Columbia
Year: 2011

description: Epithelial tissues play a critical role in maintaining systemic health by establishing a functional barrier that separates the external environment from the host to provide an innate defense against environmental insult. Epithelial barrier disruption is suspected to play a central role in the onset of chronic inflammatory disease, although, fundamental knowledge of the underlying pathogenesis remains poorly understood. Thus, identifying factors that mediate epithelial barrier loss is clinically relevant as it will open the possibility that novel interventional strategies may be developed to mitigate early disease-associated signaling events. Lipopolysaccharide (LPS) is a Gram-negative bacterial virulence factor implicated in periodontal disease onset. Amphiregulin (AR) is a ligand for the epidermal growth factor receptor (EGFR) and downstream mediator of tumor necrosis factor-alpha (TNF-α) (Chokki et al., 2006) that is normally sequestered at cell-cell contacts in stable epithelial barriers. AR and corresponding signaling components modulating the EGFR pathway are altered in a rat model of periodontal disease that exhibited concomitant altered barrier architecture (Fujita et al., 2011; Firth et al., 2011). Treatment of this model with monoamine oxidase (MAO) inhibitors ameliorated disease indices (Ekuni et al., 2009). This study employs an in vitro histiotypic model of epithelium to provide evidence that LPS-reduced epithelial barrier function associated with chronic inflammatory disease may be mediated by altered AR and TNF-α secretion. MAO-B inhibition by (−)-deprenyl enhanced barrier model transepithelial electrical resistance (TER), prevented LPS-, AR- and H₂O₂-induced reduction in TER and attenuated LPS-induced AR and TNF-α secretion and H₂O₂-induced AR secretion. Furthermore, immunostaining of barrier model cultures showed that markers of cell-cell junctions were altered by LPS challenge and treatment of the model with (−)-deprenyl protects against this disruption. This study addresses the underlying mechanism by which (−)-deprenyl protects against bacterial virulence factor-induced epithelial barrier disruption and points to a significant role for AR as a central mediator of barrier integrity. Ultimately, this project aims to provide in vitro evidence for the efficacy of (−)-deprenyl treatment of LPS-induced epithelial barrier disruption, which may promote development of enhanced MAO-B inhibitors and lead to an effective clinical treatment for disease-associated epithelial barrier loss.
Making Work Supports Work: Tools for Policy Analysis
Creators: name: National Center For Children In Poverty
Publisher: name: Columbia University
Year: 2010
Subjects: Working poor
Working poor--Government policy
Poor--Services for--Evaluation
Economic assistance, Domestic--U.S. states

description: The National Center for Children in Poverty’s (NCCP) Making Work Supports Work project is designed to identify and promote policies that make work pay for low-wage workers and their families. Millions of parents work full-time, year-round and yet struggle to provide even minimum daily necessities for their families. Government “work supports” – such as earned income tax credits, child care subsidies, health insurance, food stamps, and housing assistance – can help. These benefits encourage, support, and reward work, helping families close the gap between low wages and the cost of basic needs. To assess the effectiveness of existing state and federal work support policies, we examine how much families need to make ends meet and how public benefits impact family budgets. We then work with state partners to identify, model, and promote alternative policies that better support low-wage workers and their families. Our work draws on results from two web-based tools: the Family Resource Simulator and the Basic Needs Budget Calculator.
The experience of career practitioners in using creativity with clients : what helps and hinders
Creators: name: Mills, Lauri
Publisher: name: University of British Columbia
Year: 2011

description: This study explored the experience of career development practitioners in using creativity with their clients. Career counselling literature details a change in the landscape of work. Globalization and the unpredictable nature of the economy require a shift in the career counselling paradigm, as workers today are expected to look after their own career progression, be more flexible, and have more adaptive skills. Many authors argue that creativity is an integral part of the future of career counselling as the need to move from traditional theory to more innovative approaches and techniques becomes more apparent. The challenge for career counsellors is to find creative ways to help clients develop the tools they need to effectively navigate the modern working world. However, there is little research into how career counsellors use creativity with clients, especially with regard to what facilitates the use of creativity and what challenges its use. The results of this research study lend insight into what helps and hinders career practitioners’ use of creativity. Thirteen participants were interviewed using the Enhanced Critical Incident Technique. The study yielded 78 incidents that participants perceived as helpful to their use of creativity, 65 incidents that hindered their use of creativity, and 40 wish list items. These incidents and wish list items were grouped into 25 categories. The 10 main helping categories were: experience and knowledge, personal traits, colleagues, professional development, personal activities and methods, time, clients, work environment, collaboration with clients, and resources. The 6 main hindering categories were clients, work environment, personal factors, lack of time, professional development, and burnout. The 9 wish list categories were colleagues, supportive work environment, resources, professional development, physical work environment, time, financial security, clients, and autonomy. The findings show that a supportive work environment is significant for counsellors, as well as time and access to resources. Clients and colleagues also play an important role in the use of creativity, as do personal factors such as individual characteristics, activities and practices. Finally, the results of the study suggest professional development as a key component in counsellors’ ability to feel creative and use creativity with their clients.
“Chokin’ it down” : men’s experience of emotional inexpression
Creators: name: Hoover, Stuart Michael
Publisher: name: University of British Columbia
Year: 2011

description: Male gender socialization teaches men to resist experiencing vulnerable emotions in themselves or in others. Emotional inexpression is so foundational to the male gender role that men may be unable to express emotions, or feel compelled to “choke down” their emotions before others and within themselves. A majority of clinicians endorse greater emotional expression as desirable for men, which provides a rationale for therapeutic interventions that increase men’s emotional expressivity. However, some authors propose that men’s emotional inexpression can have adaptive qualities, such as enabling them to function under stressful or traumatic situations. The aim of this study was to step back and understand men’s experiences of maintaining emotional inexpression while feeling a strong emotional reaction arising within them. A phenomenological study was conducted with six men to explore this experience. Themes arising from this study inform theory of emotional expressivity and provide possible therapeutic interventions aimed at increasing these men’s emotional expression and lay groundwork for further studies in male emotional expression.
Fast online deconvolution of calcium imaging data
Creators: name: Friedrich, Johannes
name: Zhou, Pengcheng
name: Paninski, Liam
Publisher: name: Columbia University
Year: 2017
Subjects: Calcium
Algorithms
Optimizing compilers
Chemistry

description: Fluorescent calcium indicators are a popular means for observing the spiking activity of large neuronal populations, but extracting the activity of each neuron from raw fluorescence calcium imaging data is a nontrivial problem. We present a fast online active set method to solve this sparse non-negative deconvolution problem. Importantly, the algorithm progresses through each time series sequentially from beginning to end, thus enabling realtime online estimation of neural activity during the imaging session. Our algorithm is a generalization of the pool adjacent violators algorithm (PAVA) for isotonic regression and inherits its linear-time computational complexity. We gain remarkable increases in processing speed: more than one order of magnitude compared to currently employed state of the art convex solvers relying on interior point methods. Unlike these approaches, our method can exploit warm starts; therefore optimizing model hyperparameters only requires a handful of passes through the data. A minor modification can further improve the quality of activity inference by imposing a constraint on the minimum spike size. The algorithm enables realtime simultaneous deconvolution of O(105 ) traces of whole-brain larval zebrafish imaging data on a laptop.
Psychotic 1: Loss of Baselines for Sanity
Creators: name: Fisher, R. M.
Publisher: name: In Search of Fearlessness Research Institute
Year: 2019
Subjects: global cascading crisis
climate change
youth
mental health
future

description: Dr. R. Michael Fisher, a fearologist, explores in this series the nature and role of psychosis, or more accurately the systems of psychotic experiencing (or NPE the near psychotic experience), in the shaping of our lives and especially how we are involved in relating to the present and future realities. He is most concerned with "going through red lights" as if it is now the new 'normal' way of carrying on our daily lives as individuals and as a society. He tells a story of being in a room of the best and brightest, 500 entrepreneurs in his city recently and how no one talked about the 'elephant in the room' --that is, global cascading crisis on the scale of mass extinctions and the terror that is going with that. The very notion of "future" has to be completely re-thought and re-imagined from a new baseline, he argues, but the psychosis we are practicing is taking us so easily away from such a confrontation with reality. We are living largely in illusions which are extremely dangerous. What kind of therapeutic re-education is going to be needed to help us through this mass NPE? Dr. Fisher invites all to respond, to share, to exchange on this youtube channel or email Dr. Fisher r.michaelfisher52 [at] gmail.com p.s. I highly recommend you watch this video on youth and their critique of "climate education" https://www.youtube.com/watch?v=MXuzd...
Endothelial progenitor cells in chronic obstructive pulmonary disease and emphysema
Creators: name: Doyle, Margaret F.
name: Tracy, Russell P.
name: Parikh, Megha A.
name: Hoffman, Eric A.
name: Shimbo, Daichi
name: Austin, John H. M.
name: Smith, Benjamin M.
name: Hueper, Katja
name: Vogel-Claussen, Jens
name: Lima, Joao
name: Gomes, Antoinette
name: Watson, Karol
name: Kawut, Steven
name: Barr, R. Graham
Publisher: name: Columbia University
Year: 2017
Subjects: Endothelial cells
Stem cells
Lungs--Diseases, Obstructive
Emphysema, Pulmonary
Medicine

description: Endothelial injury is implicated in the pathogenesis of COPD and emphysema; however the role of endothelial progenitor cells (EPCs), a marker of endothelial cell repair, and circulating endothelial cells (CECs), a marker of endothelial cell injury, in COPD and its subphenotypes is unresolved. We hypothesized that endothelial progenitor cell populations would be decreased in COPD and emphysema and that circulating endothelial cells would be increased. Associations with other subphenotypes were examined. The Multi-Ethnic Study of Atherosclerosis COPD Study recruited smokers with COPD and controls age 50–79 years without clinical cardiovascular disease. Endothelial progenitor cell populations (CD34+KDR+ and CD34+KDR +CD133+ cells) and circulating endothelial cells (CD45dimCD31+CD146+CD133-) were measured by flow cytometry. COPD was defined by standard spirometric criteria. Emphysema was assessed qualitatively and quantitatively on CT. Full pulmonary function testing and expiratory CTs were measured in a subset. Among 257 participants, both endothelial progenitor cell populations, and particularly CD34+KDR+ endothelial progenitor cells, were reduced in COPD. The CD34+KDR+CD133+ endothelial progenitor cells were associated inversely with emphysema extent. Both endothelial progenitor cell populations were associated inversely with extent of panlobular emphysema and positively with diffusing capacity. Circulating endothelial cells were not significantly altered in COPD but were inversely associated with pulmonary microvascular blood flow on MRI. There was no consistent association of endothelial progenitor cells or circulating endothelial cells with measures of gas trapping. These data provide evidence that endothelial repair is impaired in COPD and suggest that this pathological process is specific to emphysema.
Wirkung von Lipopolysacchariden auf kardiale Schrittmacherkanäle vom Typ hHCN2
Creators: name: Dahm, Saskia Undine
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2019
Subjects: subject: 616

description: Die Prognose der Sepsis wird wesentlich durch den kardiovaskulären Status bestimmt. Im Rahmen der gramnegativen Sepsis kommt es zur systemischen Freisetzung von Lipopolysacchariden (Endotoxin), diese führen zu einer reduzierten Herzfrequenzvariabilität. Neben der zytokinvermittelten autonomen Dysfunktion können Lipopolysaccharide Herzmuskelzellen auch direkt beeinträchtigen. In der vorliegenden Arbeit konnte der direkte Einfluss von Lipopolysacchariden auf kardiale Schrittmacherkanäle vom Typ hHCN2, die heterolog in HEK 293-Zellen exprimiert wurden, gezeigt werden. Bei den durch Hyperpolarisation aktivierten und durch zyklische Nukleotide gesteuerten Kanälen (HCN-Kanälen) kommt es zu einer Verschiebung der spannungsabhängigen Öffnungscharakteristik in negativere Bereiche, einer erschwerten Aktivierung, erleichterten Deaktivierung und Reduktion des Maximalstroms. Klinisch könnte dies zur Bradykardie führen und zur prognostisch ungünstigen Einschränkung der Herzfrequenzvariabilität beitragen.
description: The cardiovascular state significantly determines the survival in sepsis. In gramnegative sepsis lipopolysaccharides (endotoxin) are systemically liberated and cause a decreased heart rate variability. Besides the cytokine-modulated effects that lead to autonomous dysfunction lipopolysaccharides can also directly affect cardiac cells. In this thesis the direct effect of lipopolysaccharides at the heterologously in HEK 293-cells expressed cardiac pacemaker channel hHCN2 was demonstrated. There is a shift of the voltage-gated opening characteristics to more hyperpolarized membrane potentials, reduction of the maximum current, aggravated activation and facilitated deactivation of the hyperpolarization-activated and cyclic nucleotide gated channel (IhHCN2). Clinically this could lead to bradycardia and the prognostically unfavourable reduction of the heart rate variability.
Domain Structure of Black Hole Space-Times with a Cosmological Constant
Creators: name: Armas, Jay
name: Caputa, Pawel
name: Harmark, Troels
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We generalize the domain structure for stationary black hole space-times to include asymptotically de Sitter and Anti-de Sitter space-times. Given a set of commuting Killing vector fields of a space-time the domain structure lives on the submanifold of the orbit space on which at least one of the Killing vector fields has zero norm. In general the domain structure provides topological and geometrical invariants of black hole space-times that in specific cases have proven to be a crucial part of a full characterization leading to uniqueness theorems. In four and five dimensions the domain structure generalizes the rod structure. We examine in detail the domain structure for four, five, six and seven-dimensional black hole space-times including a very general class of spherically symmetric and static black hole space-times as well as the exact solutions for Kerr-(Anti)-de Sitter black holes. While for asymptotically Anti-de Sitter space-times the domain structures resemble that of asymptotically flat space-times, the domain structures of asymptotically de Sitter space-times are shown to be compact. Finally, we find under certain assumptions that the horizon topologies for four- and five-dimensional black holes are restricted by our domain structure analysis.
description: 45 pages, 14 figures. v2: Typos fixed, ref. added
title: Effects of rearing temperature on the thermal tolerance, metabolic capacity and stress response of cultured lumpfish (Cyclopterus lumpus)
Creators: name: Eisenberg, Rachel
Publisher: name: Memorial University of Newfoundland
Year: 2023

description: Lumpfish (Cyclopterus lumpus) mortalities have been reported during the summer at some North Atlantic salmon cage-sites where they serve as ‘cleaner fish’. To understand their physiology, and whether limitations in their metabolic capacity and thermal tolerance can explain this phenomenon, I compared the aerobic scope (AS) of 6°C-acclimated lumpfish using a critical swim speed (Ucᵣᵢₜ) test, a critical thermal maximum (CTₘₐₓ) test (rate of warming 2°C h⁻¹) and a chase to exhaustion. The Ucᵣᵢₜ and CTₘₐₓ of 45-75g lumpfish were 2.36 ± 0.08 body lengths s⁻1 and 20.6 ± 0.3°C, respectively. The AS of lumpfish was higher during the Ucᵣᵢₜ test (206.4 ± 8.5 mg O₂ kg⁻¹ h⁻¹) vs. that measured in either the CTₘₐₓ test or after the chase (141.0 + 15.0 and 124.7 ± 15.5 mg O₂ kg⁻¹ h⁻¹). Next, I examined whether changing temperatures during incubation/rearing influenced the lumpfish’s AS, CTₘₐₓ and ITₘₐₓ (incremental thermal maximum, measured by warming at 0.1-0.2°C day⁻¹), and stress physiology. Temperature combinations included 6°C/9°C (that used in standard production protocols), 8.5°C/9°C, 6-11°C/9°C, 8.5°C/9-11°C and 6-11°C/9- 11°C, with ranges indicating stochastic changes. The lumpfish’s upper thermal tolerance (CTₘₐₓ, 22.85 ± 0.12°C; ITₘₐₓ, 20.63°C) and AS were not influenced by incubation or rearing temperatures, and based on these values it does not appear that cage-site mortalities during the summer are related to high water temperatures.