cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Décimas para cantarlas por el punto de La Habana: Digital edition
Creators: name: Leblanc Elina
Publisher: name: Zenodo
Year: 2021
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2022), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Décimas para cantarlas por el punto de La Habana: Digital edition
Creators: name: Leblanc Elina
Publisher: name: Zenodo
Year: 2022
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2024), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
mTORC1 and mTORC2 Differentially Regulate Cell Fate Programs to Coordinate Osteoblastic Differentiation in Mesenchymal Stromal Cells
Creators: name: Schaub, Theres
name: Gürgen, Dennis
name: Maus, Deborah
name: Lange, Claudia
name: Tarabykin, Victor
name: Dragun, Duska
name: Hegner, Björn
Publisher: name: Robert Koch-Institut
Year: 2019
Subjects: subject: Calcification
subject: Cardiovascular diseases
subject: Cell signalling
subject: End-stage renal disease
subject: 610 Medizin und Gesundheit

description: Vascular regeneration depends on intact function of progenitors of vascular smooth muscle cells such as pericytes and their circulating counterparts, mesenchymal stromal cells (MSC). Deregulated MSC differentiation and maladaptive cell fate programs associated with age and metabolic diseases may exacerbate arteriosclerosis due to excessive transformation to osteoblast-like calcifying cells. Targeting mTOR, a central controller of differentiation and cell fates, could offer novel therapeutic perspectives. In a cell culture model for osteoblastic differentiation of pluripotent human MSC we found distinct roles for mTORC1 and mTORC2 in the regulation of differentiation towards calcifying osteoblasts via cell fate programs in a temporally-controlled sequence. Activation of mTORC1 with induction of cellular senescence and apoptosis were hallmarks of transition to a calcifying phenotype. Inhibition of mTORC1 with Rapamycin elicited reciprocal activation of mTORC2, enhanced autophagy and recruited anti-apoptotic signals, conferring protection from calcification. Pharmacologic and genetic negative interference with mTORC2 function or autophagy both abolished regenerative programs but induced cellular senescence, apoptosis, and calcification. Overexpression of the mTORC2 constituent rictor revealed that enhanced mTORC2 signaling without altered mTORC1 function was sufficient to inhibit calcification. Studies in mice reproduced the in vitro effects of mTOR modulation with Rapamycin on cell fates in vascular cells in vivo. Amplification of mTORC2 signaling promotes protective cell fates including autophagy to counteract osteoblast differentiation and calcification of MSC, representing a novel mTORC2 function. Regenerative approaches aimed at modulating mTOR network activation patterns hold promise for delaying age-related vascular diseases and treatment of accelerated arteriosclerosis in chronic metabolic conditions.
Religious Belief, Religious Denomination, and Preferences for Redistribution: A Comparison across 13 Countries
Creators: name: Jordan, Jason
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Biotechnology
subject: Neuroscience
subject: Cell Biology

description: Despite clear evidence of a link between religion and welfare state development, research on public support for redistributive social policies has been slow to incorporate religion into models of public preferences. Does religious belief influence support for redistribution? If so, does religion necessarily increase hostility to redistribution as suggested by existing research? Or, do the Catholic and Protestant traditions generate different patterns of preferences consistent with Weber’s notion of a Protestant work ethic? This research explores these questions by comparing public support for redistribution across 13 European states. The data reveal a powerful and complex effect of religious belief on support for redistribution that works on both the individual and cultural levels. The evidence challenges existing research by demonstrating that the impact of religion is not uniform, but varies across different religious traditions, with Catholicism producing significantly greater support for redistribution than Protestantism.
title: L'activité physique adaptée en groupe en période péri-partum et son impact sur la dépression post-partum
title: L'activité physique adaptée en groupe en période péri-partum et son impact sur la dépression post-partum
titleType: AlternativeTitle
Creators: name: Devaud, Céline
name: Pasche, Julya
Publisher: name: Unknown
Year: 0
Subjects: subject: hesav TB PHY

description: Contexte : Lors de la pandémie de SARS-Cov-2, l’incidence de la dépression post-partum (DPP) a presque triplé. Selon notre hypothèse, les causes de cette augmentation comprendraient le manque de soutien social et la diminution de l’activité physique. L’activité physique adaptée (APA) et le groupe de soutien sont des outils déjà utilisées dans le traitement de la DPP, mais de façon isolée. Il est donc intéressant d’observer les conséquences de leur association. Notre revue expose l’impact de l’APA en groupe, lors de la période péri-partum, sur l’incidence de la DPP. Méthode : Par une recherche effectuée sur les bases de données PubMed, PEDro et CINAHL, nous avons sélectionné quatre articles ciblant notre question de recherche. Des critères d’inclusion et d’exclusion, dans la méthode de sélection des sujets, ont été définis afin de limiter les biais. Nous avons défini le score du test psychométrique Edinburgh Postnatal Depression Scale (EPDS) ≥ 9 comme la limité inférieure d’inclusion des personnes à risque de DPP. Résultats : L’activité physique adaptée en groupe est efficace, lorsqu’elle est mise en place en période post-partum, sur une population de femmes avec un score EPDS ≥ 10 pré-intervention. L’APA en groupe en période pré-partum a un impact positif sur l’incidence de la DPP chez les femmes sédentaires pré-grossesse ; en revanche, les résultats ne sont pas concluants pour les autres populations de femmes enceintes. Conclusion : Des études complémentaires sont nécessaires afin de définir des modalités et valider ou infirmer leur efficacité pour une large population.
Monkey King Sun Wukong beats the White-bone demon three times (孙悟空三打白骨精)
Creators: name: Zhao Hongben 赵宏本
Publisher: name: University of Victoria Libraries
Year: 2022
Subjects: Campaign Against Jiang Qing
Journey To The West

description: Painting depicts the celebrated incident from the 17th century novel "Journey to the West", which was used used in the late 1970s as an allegory for the overthrow of Mao’s widow Jiang Qing. Price: 14 fen
Synthesis, structural, and spectral studies of diorganotin(IV) complexes with 2–hydroxy-5-methylbenzaldehyde-N(4)-cyclohexylthiosemicarbazone
Creators: name: Rosenani A. Haque
name: M. A. Salam
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Computational Biology

description: Three new diorganotin(IV) complexes, [Me2Sn(L)] (2), [Bu2Sn(L)] (3), and [Ph2Sn(L)] (4) [where H2L (1) = 2-hydroxy-5-methylbenzaldehyde-N(4)-cyclohexylthiosemicarbazone] have been synthesized by reacting the corresponding diorganotin(IV) dichloride with H2L (1) in absolute methanol in the presence of potassium hydroxide. All the compounds have been characterized by CHN analyses, UV–vis, FT-IR, 1H, 13C, and 119Sn NMR spectroscopy. The molecular structures of H2L (1) and 2 have been confirmed by single crystal X-ray diffraction analysis. H2L (1) is found to be in the thiol tautomeric form. The X-ray structure of 2 showed that H2L is a tridentate ligand and binds to the tin(IV) atom via the phenolic oxygen, azomethine nitrogen, and thiolate sulfur. Complex 2 has a triclinic structure and the coordination geometry of tin(IV) is distorted trigonal bipyramidal. The sulfur and oxygen are in axial positions while the azomethine nitrogen of 1 and two methyl groups occupy the equatorial positions. The C-Sn-C angles determined from 1J(119Sn, 13C) for 2, 3, and 4 are 124.35°, 123.11°, and 123.82°, respectively. The values of δ(119Sn) for 2, 3, and 4 are −153.4, −180.59, and −158.3 ppm, respectively, indicating five-coordinate tin(IV). From NMR data a distorted trigonal-bipyramidal configuration at each tin is proposed.
title: Coupled Transport Processes in Zero-Gravity Distillation Columns
Creators: name: Preußer, Niklas
Publisher: name: UNSPECIFIED
Year: 2020

description: Distillation is an essential process in the chemical industry. To cope with small production quantities of specialized chemicals, modular production plants have gained increasing attention in the past years. Zero-gravity distillation is a small-scale distillation process, which offers high separation efficiencies and can be used as a part of modular production plants. Instead of gravity, capillary forces are utilized to sustain the fluid circulation. In order to apply the process in industry, the influence of the operating parameters and the capillary structure on the process variables has to be understood. In this thesis, the results of experiments and simulations of zero-gravity distillation are presented and discussed. The experimental setup, which is similar to a flat heat pipe, allows measuring the wall and vapor temperatures, the fluid composition at the condenser, the pressure, and the liquid-vapor interface shape. Two different capillary structures were investigated at infinite reflux with mixtures of water and ethanol. For the extensively studied triangular groove structure, the overall average ethanol fraction, the heat flux, and the inclination of the system were varied. Negative inclination angles indicate that the condenser lay higher than the evaporator. The separation efficiency defined as the difference between the ethanol mole fraction at the condenser and the system average ethanol mole fraction increased with decreasing overall average ethanol fraction, decreasing heat flux, and decreasing inclination angle. For the advanced rectangular groove structure, three fluid compositions were tested. By comparing the two groove structures, no clear conclusion could be drawn on which capillary structure promotes separation. In the theoretical model, heat transfer, mass transfer, and hydrodynamics are coupled for zero-gravity distillation in channel-shaped capillary structures. In contrast to existing models for porous media as capillary structures, the influence of the variation of the area occupied by the liquid along the flow direction is accounted for. Additionally, heat conduction in the channel wall is included. The theoretical model of zero-gravity distillation was applied to a re-entrant channel structure at different values of the heat flux, the inclination, and the radius of the circular part of the cross section. As in the experiments, the separation improved with decreasing heat flux, which means the difference between the ethanol mole fractions between evaporator and condenser increased. Changing the inclination of the system did not lead to changes in the distribution of the component mole fractions in the system. With decreasing the radius of the circular part of the capillary structure cross section, an improved separation was observed. Thus, an influence of the capillary structure design on the separation was shown.
title: Traduction transculturelle de l'échelle "scale of the assessment and rating of ataxia" vers le français
title: Traduction transculturelle de l'échelle "scale of the assessment and rating of ataxia" vers le français
titleType: AlternativeTitle
Creators: name: Beetschen, Agathe
name: Sutter, Eva Hermeline
Publisher: name: Unknown
Year: 0
Subjects: subject: ataxie
subject: sara
subject: traduction validation transculturelle
subject: version française
subject: hesav TB PHY

description: Introduction : L’ataxie désigne un ensemble de troubles de la coordination motrice sans parésie, touchant la direction et la quantité du mouvement, la posture et l‘équilibre. La SARA est un outil d’évaluation valide et fiable de l’ataxie. Il n’existe aucune version validée en français. Les traductions libres sont insuffisantes pour garantir la validité ; l’objectif de ce travail est d’effectuer les étapes de traduction en respectant les recommandations pour la traduction d’outils d’évaluation. Méthode : La méthode a été basée sur celle de De Vet et al. L’échelle a été traduite individuellement par deux traducteurs de langue française. Ces versions ont été mises en commun. La version obtenue a été soumise à une traduction de retour vers l’anglais. Puis la traduction française a été soumise à un comité d'experts, afin d’aboutir à un consensus pour la version pré-finale. Résultats : Les résultats consistent en la version pré-finale traduite de la SARA, ainsi qu’en les rapports, qui ont permis d‘identifier les processus décisionnels aboutissant à cette version. Ils ont été catégorisés comme suit : sémantique ; terme professionnel ; traduction littérale ; compréhension commune ; démarche clinique ; formulation populaire ; clarification ; esthétique. Conclusion : La démarche s’est avérée nécessaire et utile. Le protocole a permis de soulever des éléments qui ne l’auraient probablement pas été avec une traduction libre. Le respect du protocole devrait garantir la validité de l’échelle originale.
A Study of Building Layout Deployment on Occupant’s Energy Consumption Behaviour Using Agent-Based Modeling: An Assessment of Sustainable Behaviour Practice for Low-Income Cultural Background (Poster)
Creators: name: Uddin, Mohammad Nyme
Publisher: name: figshare
Year: 2022
Subjects: subject: 120102 Architectural Heritage and Conservation
subject: FOS: Civil engineering
subject: 120101 Architectural Design
subject: FOS: Arts (arts, history of arts, performing arts, music)
subject: 120105 Architecture Management
subject: 120199 Architecture not elsewhere classified
subject: 120201 Building Construction Management and Project Planning
subject: 120299 Building not elsewhere classified
subject: 120202 Building Science and Techniques

description: Energy consumption in buildings is affected by numerous factors including its physical characteristics, interior appliances and the outdoor environment. However, occupant’s behaviour that determines and regulates the building energy consumption must not be forgotten. Most of the earlier studies, occupant behaviour is modelled as static or fixed occupancy profiles. These profiles are acknowledged as the main source of discrepancy between the predicted and actual building energy performance. Several studies have been performed to understand the factors affecting occupant sustainable energy behaviours in regard to climate, social, economics, regulations and personal aspects. In addition, building space layout deployment has various impacts on occupant sustainable energy consumption behaviour as well as their interaction with the building energy system. So, this study highlighted the impact of space layout on occupant energy behaviour using Agent-Based Modeling (ABM) approach. The ABM demonstrated a considerable amount of building energy savings while using a sustainable space layout configuration. The energy consumptions data obtained from the ABM further validated using the real data collected from the smart meter. This study will help to understand the proper space layout configurations, occupant movements and their choice of behavioural intentions of building energy savings for a low-income cultural background.
Synthesis, structural and spectral studies of diorganotin(IV) complexes with 2-hydroxy-5-methylbenzaldehyde-N(4)-cyclohexylthiosemicarbazone
Creators: name: Rosenani A. Haque
name: M. A. Salam
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Chemistry
Biotechnology
Physics
Biochemistry
Biophysics

description: Three new diorganotin(IV) complexes, [Me2Sn(L)] (2), [Bu2Sn(L)] (3) and [Ph2Sn(L)] (4) [where H2L (1) = 2-hydroxy-5-methylbenzaldehyde-N(4)-cyclohexylthiosemicarbazone], have been synthesized by reacting the corresponding diorganotin(IV) dichloride with H2L (1) in absolute methanol in the presence of potassium hydroxide. All the compounds have been characterized by CHN analyses, UV-Vis, FT-IR, 1H, 13C and 119Sn NMR spectroscopy. The molecular structures of H2L (1) and 2 have been confirmed by single crystal X-ray diffraction analysis. H2L (1) is found to be in the thiol tautomeric form. The X-ray structure of 2 showed that H2L is a tridentate ligand and binds to the tin(IV) atom via the phenolic oxygen, azomethine nitrogen and thiolate sulphur. Complex 2 has a triclinic structure and the coordination geometry of tin(IV) is distorted trigonal bipyramidal. The sulphur and oxygen are in axial positions while the azomethine nitrogen of 1 and two methyl groups occupy the equatorial positions. The C-Sn-C angles determined from 1J(119Sn, 13C) for 2, 3 and 4 are 124.35, 123.11 and 123.82°, respectively. The values of δ(119Sn)) for 2, 3 and 4 are -153.4, -180.59 and -158.3 ppm, respectively, indicating five-coordinate tin(IV). From NMR data a distorted trigonal-bipyramidal configuration at each tin is proposed.
Brentuximab vedotin compared with other therapies in relapsed/refractory Hodgkin lymphoma post autologous stem cell transplant: median overall survival meta-analysis
Creators: name: Vijayveer Bonthapally
name: Hongbo Yang
name: Ayyagari, Rajeev
name: Ruo-Ding Tan
name: Cai, Sean
name: Wu, Eric
name: Gautam, Ashish
name: Chi, Andy
name: Huebner, Dirk
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: This meta-analysis compared the median overall survival (mOS) of brentuximab vedotin reported in the pivotal phase 2 study with published results of other therapies for the treatment of relapsed/refractory (R/R) Hodgkin lymphoma (HL) post autologous stem cell transplant (ASCT). A systematic literature review identified studies that reported survival outcomes following conventional/experimental therapies in R/R HL patients, with ≥50% having failed ≥1 ASCT. Kaplan–Meier curves were used to reconstruct individual patient level survival data. Patients were grouped by treatment type and reconstructed data were used to estimate the mOS. Censored median regression modeling was used to compare mOS in each group with the mOS in the pivotal brentuximab vedotin trial. All patients in the pivotal trial had undergone ASCT, therefore a sensitivity analysis was conducted among studies with a 100% post-ASCT patient population. The mOS reported for brentuximab vedotin was 40.5 (95% CI 30.8–NA) compared with 26.4 months (95% CI 23.5–28.5) across all 40 studies identified (n = 2518 excluding the brentuximab vedotin trial) (p p p p = 0.0037), respectively. For the 11 studies reporting a 100% prior-ASCT rate (n = 662 excluding the brentuximab vedotin trial), the mOS was 28.1 months (95% CI 23.9–34.5), and the difference in mOS between brentuximab vedotin, chemotherapy, allo-SCT, and other therapies was 19.0 (95% CI 12.9–25.1; p p > 0.05), and 6.8 months (95% CI 1.2–12.5; p = 0.0018), respectively. While some selection bias may occur when comparing trials with heterogeneous eligibility criteria, in the absence of randomized controlled trial data these results suggest brentuximab vedotin improves long-term survival and is associated with longer mOS in R/R HL post-ASCT compared with other therapies.
VISUALIZZA O SCARICA IL VOLUME COMPLETO
Creators: name: Prova Fascicolo Come Autore
Publisher: name: Italiano LinguaDue
Year: 2020

description: Fascicolo completo UNO STANDARD VARIABILE. LINEE EVOLUTIVE E MODELLI DI LETTURA DELLA LINGUA D'OGGI Atti del convegno di studi - Università degli Studi di Milano, 22-23 novembre 2017 a cura di Massimo Prada e Giuseppe Polimeni
description: Italiano LinguaDue, V. 11 N. 1 (2019)
การป้องกันควบคุมโรคชายแดนไทย-เมียนมาร์ โดยองค์การบริหารส่วนตำบล
Creators: name: จุฑาทิพย์ ชมภูนุช
Publisher: name: สำนักจัดการความรู้ กรมควบคุมโรค กระทรวงสาธารณสุข
Year: 2556
Subjects: องค์การบริหารส่วนตำบล
การป้องกันควบคุมโรค

description: วารสารควบคุมโรค, 39, 4, 281-288
title: Basic Body Awareness therapy
title: État des connaissances et domaines d'application
titleType: Subtitle
title: Basic Body Awareness therapy
titleType: AlternativeTitle
Creators: name: Roch, Coline
name: Schenk, Mélisande
Publisher: name: Unknown
Year: 0
Subjects: subject: body awareness therapy
subject: pleine conscience
subject: troubles psychiatriques
subject: scoliose idiopathique
subject: variabilité cardiaque
subject: approche holistique
subject: hesav TB PHY

description: Introduction : La Basic Body Awareness Therapy est une thérapie développée dans les pays scandinaves qui combine le mouvement et la pleine conscience. Elle a été étudiée sur diverses populations que ce soit dans un but thérapeutique ou préventif. En l’absence de revue systématique et de données suffisamment homogènes à propos de la BBAT, ce travail de Bachelor a cherché à identifier dans quel cas de figure et avec quelle modalité cette thérapie est utilisée à l’heure actuelle. Méthode : Une Scoping Review a été réalisée, afin de proposer une vue d’ensemble concernant ce sujet. Quatre articles ont été retenu qui traitent d’une diversité de population ayant pratiqué la BBAT sur une durée d’intervention variable. Résultats : Divers objectifs thérapeutiques et modalités ont respectivement été poursuivi et appliqué en fonction des objectifs de recherche de chaque article sélectionné. La population la plus représentée dans notre échantillon est constituée de femmes. Conclusion : La thérapie offre une prise en charge sur mesure en fonction des individus la pratiquant. Ce serait l’une des raisons pour lesquelles il n’y pas de consensus prédéfini de ses modalités. Concernant la population d’intérêt, l’application de cette thérapie auprès des personnes saines dans un but préventif donne matière à réflexion dans l’optique de futures recherches.
LE VARIETÀ LINGUISTICHE IN CONTESTO INFORMALE: UNO STUDIO DI CASO DI UNA FAMIGLIA ITALIANA IN BRASILE
Creators: name: Ferroni, Roberta
name: Amenta, Luisa
Publisher: name: Italiano LinguaDue
Year: 2020

description: L’obiettivo di questa indagine è di documentare le varietà linguistiche in uso in un contesto intrafamiliare di tipo informale. Lo studio di caso che presentiamo ha come protagonisti i membri di una famiglia veneta con un livello di qualificazione medio-alta che in seguito all’ultima grande crisi economica mondiale del 2008 si sono trasferiti in Brasile. Questa indagine si inserisce all’interno degli studi sull’ecologia linguistica in contesti familiari e si è basata sull’analisi di una videoregistrazione avvenuta nel corso della consumazione del pranzo e di un questionario. L’analisi mostra che anche se l’italiano rimane il codice prevalente per tutti i membri della famiglia si nota una disinvoltura da un codice ad un altro (italiano, veneto e portoghese) che apre spazi a riflessioni metalinguistiche a livello lessicale. I codici del repertorio acquistano uno spazio di sovrapposizione ma al tempo stesso di demarcazione dei confini identitari laddove si voglia sottolineare la propria distanza dalla cultura ospite, ma anche in questo caso la commutazione avviene a seguito di una precisa volontà comunicativa. Il caso studio osservato permette di far emergere come nel caso di un plurilinguismo vissuto in termini di arricchimento tra le varietà del repertorio italiano/dialetto di cui dispongono i parlanti, l’inserimento della lingua del paese ospite si inserisce come ulteriore elemento di ricchezza accanto alla lingua di origine. Language varieties in an informal context: a case study of an italian family in Brazil The aim of this survey is to document the language varieties used in an informal intra-family context. The case study focuses on a family with a medium-high level of education from the Veneto Region who, following the last major world economic crisis of 2008, moved to Brazil. This survey falls within studies on linguistic ecology in family contexts and is based on the analysis of a video recording made during a lunch and a questionnaire. The analysis shows that even if Italian remains the prevailing code for all family members, there is a casualness from one code to another (Italian, Venetian dialect and Portuguese) that creates space for metalinguistic reflections at the lexical level. The codes of the repertory overlap but at the same time there are clear boundaries that emphasize the distance from the host culture, although the switching takes place following a precise communicative will. The case study observed highlights how in the case of multilingualism experienced in terms of enrichment among the varieties of the Italian repertoire / dialect available to the speakers, the inclusion of the language of the host country becomes a further element of wealth in addition to the language of origin.
description: Italiano LinguaDue, V. 11 N. 2 (2019)
Religious Belief, Religious Denomination, and Preferences for Redistribution: A Comparison across 13 Countries
Creators: name: Jordan, Jason
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Biotechnology
subject: Neuroscience
subject: Cell Biology

description: Despite clear evidence of a link between religion and welfare state development, research on public support for redistributive social policies has been slow to incorporate religion into models of public preferences. Does religious belief influence support for redistribution? If so, does religion necessarily increase hostility to redistribution as suggested by existing research? Or, do the Catholic and Protestant traditions generate different patterns of preferences consistent with Weber’s notion of a Protestant work ethic? This research explores these questions by comparing public support for redistribution across 13 European states. The data reveal a powerful and complex effect of religious belief on support for redistribution that works on both the individual and cultural levels. The evidence challenges existing research by demonstrating that the impact of religion is not uniform, but varies across different religious traditions, with Catholicism producing significantly greater support for redistribution than Protestantism.
title: L'obésité en Suisse romande
title: deux exemples de prise en charge
titleType: Subtitle
title: L'obésité en Suisse romande
titleType: AlternativeTitle
Creators: name: Karoubi, Jody
name: Mazzocchin, Laura
Publisher: name: Unknown
Year: 0
Subjects: subject: hesav TB PHY

description: Introduction : Plusieurs études ont abordé la physiothérapie au sein des centres de traitement de l’obésité, mais toujours en se focalisant sur des aspects très spécifiques des soins. Aucune d’entre elles ne donnait une image générale de la prise en charge. Objectif : Il s’agit d’une étude de cas qualitative descriptive, visant à donner une image globale de la prise en charge de l’obésité dans deux centres Suisse romands. Méthode : En se basant sur un guide d’entretien semi-structuré, des questions ont été posées à des soignants afin de comprendre le fonctionnement, les enjeux, ainsi que les valeurs de ces centres. Ces entretiens ont ensuite été analysés en suivant la méthode de Paillé et Mucchielli (2019). Résultats et discussion : Le fonctionnement des centres visités est très proche des recommandations européennes et suisses de Durrer Schutz et al. (2019) et Laederach et al. (2017). Les objectifs de traitement sont la levée des obstacles à la perte de poids, la mise en place d’habitudes de vie saines sur le long terme et l’autonomisation. Pour aider les patients, trois outils sont principalement utilisés : la psychothérapie, l’activité physique et la nutrition. Les soins sont centrés sur le patient afin d’être au plus proche de ses besoins et attentes. Les soignants visent l’interprofessionnalité et une communication optimale de manière à partager l’expertise de chacun au bénéfice des patients. Les obstacles mis en évidence dans le système suisse sont la faible place laissée à la prévention, ainsi que la difficulté de remboursement de certaines prestations.
Isostructural Softening of Vulcanized Nanocomposites
Creators: name: Baeza, Guilhem P.
name: Dalmas, Florent
name: Dutertre, Fabien
name: Majesté, Jean-Charles
Publisher: name: arXiv
Year: 2024
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Following a previous work evidencing that short poly-propylene glycol (PPG) chains incorporated to crude SBR-silica nanocomposites act as filler-network softeners without changing their structure, we propose in the present letter to examine more operative cross-linked materials. We first evidence that the adsorption of PPG onto silica deactivates progressively the particle's catalytic effect on vulcanization, without perturbing however the cross-link density distribution that we investigate through multiple-quantum NMR. In addition, electron microscopy confirms that silica structure is conserved after vulcanization and that it does not depend on the PPG content either. Composites containing various amount of PPG can thus be seen as structurally identical, both from a matrix and filler point of view - which is confirmed by small and medium amplitude oscillation shear rheology showing strikingly identical viscoelastic properties. PPG signature only appears above 100% in tensile deformation where it is seen to soften dramatically the filler network. Our discovery makes it consequently possible to decorrelate the mechanical behavior of reinforced rubbers under normal conditions of use and urgent needs of energy dissipation.
Incidence of ischemic stroke or transient ischemic attack in patients with multiple risk factors with or without atrial fibrillation: a retrospective cohort study
Creators: name: Yuan, Zhong
name: Makadia, Rupa
name: Ryan, Patrick
name: Yannicelli, Daniel
name: Nessel, Christopher
name: Sarich, Troy
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology
subject: Computational Biology

description: The risk of stroke in atrial fibrillation (AF) increases with number of risk factors (RFs). However, the combined effect from multiple RFs on the incidence of ischemic stroke and transient ischemic attack (TIA) among US patients without AF has not been fully examined. Truven MarketScan Medicare Supplemental database was used to establish cohorts of patients ≥65 years old with and without AF. Index date was first occurrence of AF diagnosis (AF patients) or first medical encounter (non-AF patients) during the inception period from 2010 through 2011. Incidences of ischemic stroke/TIA in relation to number of baseline RFs (congestive heart failure, hypertension, advanced age, diabetes, and prior stroke/TIA, myocardial infarction) were determined during the follow-up period from the index date through March 2013. A total of 158,199 patients were included in the AF cohort and 1,181,273 patients in the non-AF cohort. Approximately 51% of AF patients had ≥3 RFs versus 18% in non-AF patients. Ischemic stroke/TIA were observed in 24,680 and 104,154 patients in the AF and non-AF cohorts, yielding incidence rate (SD) of 7.3 (0.05) and 3.2 (0.01) per 100 person-years, respectively. In the AF cohort, incidence rate of ischemic stroke/TIA was 2.3, 4.9, 9.4, and 16.9 per 100-person years for 0, 1–2, 3–4, and 5–6 RFs, respectively, compared with the corresponding rate of 1.3, 2.8, 6.4, and 12.3 per 100 person-years for the non-AF cohort. This positive association between the number of risk factors and incidence rates within each cohort was consistently observed in sensitivity analyses. In a large cohort of elderly patients without AF, the risk of ischemic stroke/TIA increased substantially in the presence of multiple RFs, highlighting potentially unmet medical needs. This observation implies that future studies may be warranted to investigate the effect of prophylactic anticoagulation in high risk non-AF patients.
Utility values in diabetic kidney disease: a literature review
Creators: name: Kennedy-Martin, Tessa
name: Rosirene Paczkowski
name: Rayner, Sharon
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Science Policy

description: To summarize the published literature on utilities for health states associated with diabetic kidney disease (DKD), including end-stage renal disease (ESRD). A literature review was conducted (MEDLINE, MEDLINE in process, EMBASE, NHS EED, HEED, CEA Registry, EconLit, RePEc, and HTA) to identify relevant articles published between January 2000 and July 2013. Results were assessed for relevance by two reviewers in line with the study protocol. For eligible studies, data extracted included patient population, health states, methods used to elicit utility values, and the source of the preference values. Twelve studies satisfied the inclusion criteria. They reported various utility and/or disutility scores for different DKD health states using a range of patient populations, utility approaches, and sources of preference values. The most common study country was the USA. Most of the studies collected data at one time point, but two had a longitudinal design. Three different utility instruments – EuroQoL (EQ-5D), Quality of Well-Being Scale (QWB), and 15-dimensional (15D) – were used to elicit utilities indirectly. The Time Trade-Off (TTO) approach was used in one study; another undertook a meta-analysis of published utility studies. Utilities were identified for different health states including DKD, ESRD–no dialysis, ESRD–dialysis, and transplant. One study reported utilities for patients by type of transplant. There was variation in values for the same health state between studies, and none of the studies reported utilities for the different stages of DKD. In the studies that undertook a comparison, utility values for those with DKD were generally found to be lower than those without DKD. This literature review highlights that at present utility scores (or disutility penalties) exist for relatively few health states in DKD. Further studies are needed to produce accurate and comprehensive utility scores that differentiate between different DKD health states.
Clinical trial transparency update: an assessment of the disclosure of results of company-sponsored trials associated with new medicines approved in Europe in 2012
Creators: name: Rawal, Bina
name: Deane, Bryan R.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Background: The objective of this study was to assess the timely disclosure of results of company-sponsored clinical trials related to all new medicines approved by the European Medicines Agency (EMA) during 2012. This is an extension of the previously reported study of trials related to all new medicines approved in Europe in 2009, 2010 and 2011, which found that over three-quarters of all these trials were disclosed within 12 months and almost 90% were disclosed by the end of the study. Methods: The methodology used was exactly as previously reported. Various publicly available information sources were searched for both clinical trial registration and disclosure of results. All completed company-sponsored trials related to each new medicine approved for marketing by the EMA in 2012, carried out in patients and recorded on a clinical trials registry and/or included in an EMA European Public Assessment Report (EPAR), were included. Information sources were searched between 1 May and 31 July 2014. Outcome measures and results: The main outcome measure was the proportion of trials for which results had been disclosed on a registry or in the scientific literature either within 12 months of the later of either first regulatory approval or trial completion, or by 31 July 2014 (end of survey). Of the completed trials associated with 23 new medicines licensed to 17 different companies in 2012, results of 90% (307/340) had been disclosed within 12 months, and results of 92% (312/340) had been disclosed by 31 July 2014. Conclusions: The disclosure rate within 12 months of 90% suggests the industry is now achieving disclosure in a timely manner more consistently than before. The overall disclosure rate at study end of 92% indicates that the improvement in transparency amongst company-sponsored trials has been maintained in the trials associated with new medicines approved in 2012.
PyExoCross: a Python program for generating spectra and cross-sections from molecular line lists
Creators: name: Zhang, Jingxin
name: Tennyson, Jonathan
name: Yurchenko, Sergei N.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: PyExoCross is a Python adaptation of the ExoCross Fortran application, PyExoCross is designed for postprocessing the huge molecular line lists generated by the ExoMol project and other similar initiatives such as the HITRAN and HITEMP databases. PyExoCross generates absorption and emission stick spectra, cross-sections, and other properties (partition functions, specific heats, cooling functions, lifetimes, and oscillator strengths) based on molecular line lists. PyExoCross calculates cross-sections with four line profiles: Doppler, Gaussian, Lorentzian, and Voigt profiles in both sampling and binned methods; a number of options are available for computing Voigt profiles which we test for speed and accuracy. PyExoCross supports importing and exporting line lists in the ExoMol and HITRAN/HITEMP formats. PyExoCross also provides conversion between the ExoMol and HITRAN data formats. In addition, PyExoCross has extra code for users to automate the batch download of line list files from the ExoMol database.
description: This version contains some minor corrections compared to the published version; 33 pages; and 13 high-resolution figures
TalkyCars: A Distributed Software Platform for Cooperative Perception among Connected Autonomous Vehicles based on Cellular-V2X Communication
Creators: name: Mütsch, Ferdinand
Publisher: name: Karlsruhe
Year: 2020

description: Autonomous vehicles are required to operate among highly mixed traffic during their early market-introduction phase, solely relying on local sensory with limited range. Exhaustively comprehending and navigating complex urban environments is potentially not feasible with sufficient reliability using the aforesaid approach. Addressing this challenge, intelligent vehicles can virtually increase their perception range beyond their line of sight by utilizing Vehicle-to-Everything (V2X) communication with surrounding traffic participants to perform cooperative perception. Since existing solutions face a variety of limitations, including lack of comprehensiveness, universality and scalability, this thesis aims to conceptualize, implement and evaluate an end-to-end cooperative perception system using novel techniques. A comprehensive yet extensible modeling approach for dynamic traffic scenes is proposed first, which is based on probabilistic entity-relationship models, accounts for uncertain environments and combines low-level attributes with high-level relational- and semantic knowledge in a generic way. Second, the design of a holistic, distributed software architecture based on edge computing principles is proposed as a foundation for multi-vehicle high-level sensor fusion. In contrast to most existing approaches, the presented solution is designed to rely on Cellular-V2X communication in 5G networks and employs geographically distributed fusion nodes as part of a client-server configuration. A modular proof-of-concept implementation is evaluated in different simulated scenarios to assess the system's performance both qualitatively and quantitatively. Experimental results show that the proposed system scales adequately to meet certain minimum requirements and yields an average improvement in overall perception quality of approximately 27 %.
title: Effets des fuites non-intentionnelles sur la synchronisation expiratoire patient-ventilateur en VNI (mode VS-AI)
title: évaluation d'un trigger expiratoire automatique sur banc d'essai
titleType: Subtitle
title: Effets des fuites non-intentionnelles sur la synchronisation expiratoire patient-ventilateur en VNI (mode VS-AI)
titleType: AlternativeTitle
Creators: name: Gétaz, Sophie
name: Müller, Laura
Publisher: name: Unknown
Year: 0
Subjects: subject: hesav TB PHY

description: Introduction : Les fuites non-intentionnelles peuvent être source d’asynchronie patient-ventilateur en ventilation non-invasive à deux niveaux de pression (VNI-2P). Pour pallier ce problème, des algorithmes automatiques permettant notamment d’optimiser les réglages de trigger expiratoire ont été développés. But : L’objectif de notre travail était d’analyser les effets des fuites non-intentionnelles en VNI-2P sur la synchronisation expiratoire patient-ventilateur d’un algorithme de trigger automatique dans différentes conditions de mécaniques respiratoires. Méthode : Le trigger expiratoire automatique était évalué avec quatre différents niveaux de fuites non-intentionnelles (0 L/min, 15 L/min, 25 L/min, 36 L/min) sur un modèle pulmonaire informatisé simulant trois mécaniques respiratoires (normale, restrictive, obstructive) à une fréquence respiratoire de 15 et 25 cycles/minute. Ceci afin de déterminer l’influence de ces fuites sur les déphasages expiratoires patient-ventilateur. Résultats : Nos résultats indiquent que les taux de fuites non-intentionnelles influencent le cyclage. Généralement, plus le taux de fuites augmente, plus le déphasage est important. Il existe également une différence significative (p<0,001) présente entre les déphasages des trois mécaniques respiratoires indépendamment des quatre niveaux de fuites. Nos résultats suggèrent que la mécanique respiratoire obstructive serait plus sensible à la variation de fuites non-intentionnelles que celle restrictive. Ceci, car la différence entre le déphasage le plus important et le moins important est environ deux fois plus grande en condition obstructive en comparaison avec celle restrictive. Conclusion : L’algorithme de trigger automatique semble plus adapté pour les patients restrictifs avec une fréquence respiratoire élevée et cela pour tous les niveaux de fuites.
Brentuximab vedotin compared with other therapies in relapsed/refractory Hodgkin lymphoma post autologous stem cell transplant: median overall survival meta-analysis
Creators: name: Vijayveer Bonthapally
name: Hongbo Yang
name: Ayyagari, Rajeev
name: Ruo-Ding Tan
name: Cai, Sean
name: Wu, Eric
name: Gautam, Ashish
name: Chi, Andy
name: Huebner, Dirk
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Science Policy
Cancer
Biological Sciences
Biotechnology
Cell Biology
Medicine

description: Objective:This meta-analysis compared the median overall survival (mOS) of brentuximab vedotin reported in the pivotal phase 2 study with published results of other therapies for the treatment of relapsed/refractory (R/R) Hodgkin lymphoma (HL) post autologous stem cell transplant (ASCT).Research design and methods:A systematic literature review identified studies that reported survival outcomes following conventional/experimental therapies in R/R HL patients, with ≥50% having failed ≥1 ASCT. Kaplan–Meier curves were used to reconstruct individual patient level survival data. Patients were grouped by treatment type and reconstructed data were used to estimate the mOS. Censored median regression modeling was used to compare mOS in each group with the mOS in the pivotal brentuximab vedotin trial. All patients in the pivotal trial had undergone ASCT, therefore a sensitivity analysis was conducted among studies with a 100% post-ASCT patient population.Results:The mOS reported for brentuximab vedotin was 40.5 (95% CI 30.8–NA) compared with 26.4 months (95% CI 23.5–28.5) across all 40 studies identified (n = 2518 excluding the brentuximab vedotin trial) (p p p p = 0.0037), respectively. For the 11 studies reporting a 100% prior-ASCT rate (n = 662 excluding the brentuximab vedotin trial), the mOS was 28.1 months (95% CI 23.9–34.5), and the difference in mOS between brentuximab vedotin, chemotherapy, allo-SCT, and other therapies was 19.0 (95% CI 12.9–25.1; p p > 0.05), and 6.8 months (95% CI 1.2–12.5; p = 0.0018), respectively.Conclusions:While some selection bias may occur when comparing trials with heterogeneous eligibility criteria, in the absence of randomized controlled trial data these results suggest brentuximab vedotin improves long-term survival and is associated with longer mOS in R/R HL post-ASCT compared with other therapies.