cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals
Creators: name: Yuan, Jia
name: Zhang, Ying
name: Sheng, Yue
name: Xiazhou Fu
name: Hanhua Cheng
name: Rongjia Zhou
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Developmental Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Astronomy, Astrophysics, Space Science
subject: Chemistry
subject: Pharmacology
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Genetics
subject: Cell Biology

description: Oogenesis is essential for female gamete production in mammals. The total number of ovarian follicles is determined early in life and production of ovarian oocytes is thought to stop during the lifetime. However, the molecular mechanisms underling oogenesis, particularly autophagy regulation in the ovary, remain largely unknown. Here, we reveal an important MYBL2-VDAC2-BECN1-BCL2L1 pathway linking autophagy suppression in the developing ovary. The transcription factors GATA1 and MYBL2 can bind to and activate the Vdac2 promoter. MYBL2 regulates the spatiotemporal expression of VDAC2 in the developing ovary. Strikingly, in the VDAC2 transgenic pigs (Sus scrofa/Ss), VDAC2 exerts its function by inhibiting autophagy in the ovary. In contrast, Vdac2 knockout promotes autophagy. Moreover, VDAC2-mediated autophagy suppression is dependent on its interactions with both BECN1 and BCL2L1 to stabilize the BECN1 and BCL2L1 complex, suggesting VDAC2 as an autophagy suppressor in the pathway. Our findings provide a functional connection among the VDAC2, MYBL2, the BECN1-BCL2L1 pathway and autophagy suppression in the developing ovary, which is implicated in improving female fecundity.
Human Rights for Sale? A Study on the Uyghur Issue and Chinese Concessional Aid
Creators: name: Yinusa, Joseph
Publisher: name: GVPT Research Assistantship Program Symposium
Year: 2019
Subjects: Government & Politics
BSOS
Yinusa
GVPT Research Assistantship Program
International Relations

description: The Uyghur issue refers to the ongoing internment by the People’s Republic of China’s government on their native Uyghur ethnic group, who primarily reside in the Xinjiang Province. Such activities are internationally considered an attack on human rights; however, many countries have defended the PRC actions on this subject, some of which receive heavy amounts of aid from the Asian country. The current paper creates a model to determine the likelihood for countries to support China’s actions in Xinjiang. The paper finds that while there is a strong relationship between receipt of aid and predictability for defending or criticizing the PRC’s internment activities, it appears that regime type is a more adept, more evident predictor.
Recommendations for enhancing the implementation and utility of shared digital health records in rural Australian communities
Creators: name: Almond, Helen
name: Cummings, E.
name: Turner, P.
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 420308
subject: Health informatics and information systems

description: Internationally, shared digital health records are becoming an important addition to improving contemporary healthcare provision. In 2012, Australia launched its version of a shared digital health record, My Health Record, but enrolment is slow and there remain challenges in its practical implementation. Further, people living with complex and chronic conditions in rural and remote communities often experience challenges in obtaining equitable access to contemporary healthcare provision, including eHealth services. This paper reports on research that explored the experience of and engagement with My Health Record, in a rural Australian community setting. Based on the key research findings, recommendations are presented for improving national roll out of My Health Record. The findings highlight, to understand and engage vulnerable communities and support their adoption and use of shared digital health records, there is a need to move away from traditional models of healthcare delivery toward person-centred care delivered from a digital complex adaptive systems perspective.
Integrating social impact throughout an engineering curriculum
Creators: name: Daniel, Scott
name: Mann, Llew
Publisher: name: Swinburne
Year: 2024

description: CONTEXT The potential that engineering offers of making a positive impact on society motivates many students, yet most university courses only appeal explicitly to this motivation through add-on global experience or service-learning programs. Furthermore, there is an increasing body of research showing that such Social Impact programs lead to improved student outcomes, especially in the development of the professional skill-sets and mind-sets required in the 21st century engineering workforce. At Swinburne University of Technology, social impact is being integrated and embedded in a new curriculum, co-designed with industry partners, grounded in education research, and built around work-oriented pedagogies including project-based learning. Projects will be aligned with 4 Pillars: Emerging Technologies, Entrepreneurship, research & Development (research in lowercase to indicate the emphasis on Development), and Social Impact. This paper reports on the process of incorporating Social Impact into this new curriculum. PURPOSE How can Social Impact be integrated throughout an engineering curriculum? APPROACH Building from an industry co-design process of identifying and unpacking the suite of skills required to succeed and flourish as an engineering graduate, the next stage is developing the curriculum and learning experiences that will enable students to acquire these skills. Within the context of Social Impact, this process involves consulting the education research literature on developing these skills, input from prospective Social Impact project partners, comparison with related project-based and service-learning programs, and then further consultation and validation with industry stakeholders. RESULTS Several milestones have been reached in developing the Social Impact curriculum pillar. The key aspects distinguishing it from the other pillars have been identified as empathising and communicating with people from diverse backgrounds. A system of micro-credentials will be used as a framework for developing students’ skills, and some of these, such as human-centred design, thinking globally, and embracing diversity, have been mapped to Social Impact. At the time of writing, a Deep Dive curriculum workshop had just been held with industry stakeholders – the outcomes and analysis will be presented at the conference, along with an update on the curriculum development process. CONCLUSIONS By incorporating lessons learned from other programs around the world, evidence-based teaching strategies from the research literature, and ongoing consultation with prospective project partners and industry stakeholders, Swinburne University of Technology is in the process of developing a world-class new initiative to integrate Social Impact throughout the engineering curriculum.
MPEC 2024-E92 : 2021 LZ43
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Linear and Nonlinear Structure-Retention Relationship Analysis of Different Classes of Pesticides Isolated From Groundwater
Creators: name: Strahinja Z. Kovačević
name: Podunavac-Kuzmanović, Sanja O.
name: Jevrić, Lidija R.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Chemistry
subject: Biotechnology

description: The present article gives an insight into the linear and nonlinear relationships between the retention behavior in reversed-phase high performance liquid chromatography (RP-HPLC) of several classes of pesticides isolated from groundwater, and their in silico physicochemical, topological and lipophilicity molecular descriptors. The quantitative structure-retention relationship (QSRR) chemometric approach was applied for this purpose on a large set of compounds (77 pesticides). The selection of the most appropriate molecular descriptors was achieved by stepwise selection procedure coupled with partial least squares method and the variance inflation in projection parameter (SS-PLS-VIP). QSRR included the linear regression (LR), multiple linear regession (MLR), and artificial neural networks regression (ANN-R). In order to select the optimal QSRR model, statistical validation parameters were used. Additionally, a relatively new chemometric method called sum of ranking differences (SRD) was applied in order to select the optimal regression model. The obtained results showed that certain models can successfully be used for precise prediction of the retention time of the studied compounds.
Linear and Nonlinear Structure–Retention Relationship Analysis of Different Classes of Pesticides Isolated From Groundwater
Creators: name: Strahinja Z. Kovačević
name: Podunavac-Kuzmanović, Sanja O.
name: Jevrić, Lidija R.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Chemistry
subject: Biotechnology

description: ABSTRACTThe present paper gives an insight into the linear and nonlinear relationships between the retention behavior in reversed-phase high performance liquid chromatography (RP-HPLC) of several classes of pesticides isolated from groundwater, and their in silico physicochemical, topological and lipophilicity molecular descriptors. The quantitative structure-retention relationship (QSRR) chemometric approach was applied for this purpose on a large set of compounds (77 pesticides). The selection of the most appropriate molecular descriptors was achieved by stepwise selection procedure coupled with partial least squares method and the variance inflation in projection parameter (SS-PLS-VIP). QSRR included the linear regression (LR), multiple linear regession (MLR) and artificial neural networks regression (ANN-R). In order to select the optimal QSRR model, statistical validation parameters were used. Besides, a relatively new chemometric method called sum of ranking differences (SRD) was applied in order to select the optimal regression model. The obtained results showed that certain models can successfully be used for precise prediction of the retention time of the studied compounds.
The concentration, assay, and properties of avidin
Creators: name: Eakin, Robert Edward, 1916-
Publisher: name: The University of Texas at Austin
Year: 1942
Subjects: subject: Avidin--Properties

description: The material in this dissertation gives in detail the assay method developed for avidin and the procedures used in its concentration. The results of physiological and chemical studies on the protein and its biotin complex are also reported
Laser cladding of high strength aluminium alloy 7075 powder on a 7075 substrate for repair of damged components
Creators: name: Cottam, Ryan
name: Liu, Q.
name: Wong, Yat
name: Wang, James
name: Brandt, Milan
Publisher: name: Swinburne
Year: 2024

description: Laser cladding is a surface engineering technique that has been employed in this investigation to develop a repair technique for high strength aluminium alloy components. High strength aluminium alloys are used in a variety of situations due to their good combination of high strength and low density. Repair of such components has the potential for cost savings for both the defence and aerospace sectors. Aluminium alloy 7075 powder was laser clad onto a substrate of 7075 and the character of the microstructure in both the clad layer and heat affected zone was evaluated. It was found that the fine precipitates that provide the strength in this class of alloy had grown and coalesced due to the heat supplied by the laser and weakened the heat affected zone from a structural point of view. A solution heat treatment and T6 aging procedure was applied to restore the strength in this region. After the heat treatment, hardness traverse profiles revealed that the hardness in the clad layer was lower than that of the substrate. This was attributed to the evaporation of magnesium and zinc during cladding and the higher concentration of iron in the powder forming an insoluble phase with zinc and magnesium in the clad layer. Both of these factors ultimately reduce the volume of the strengthening phases.
ELECTRODES FOR SUPER CAPACITORS
Creators: name: J, SHOBA
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 401807
subject: Nanomaterials

description: The current study is to synthesize the electrode materials for super capacitors.Transition metal oxides of nano scale are prepared using hydro thermal methods at 160, 180, 200 deg .The morphology( XRD, SEM) and electro chemical behaviour( CV, GCD, IMPEDANCE) is tested.
Optical tweezers for velocity mapping in microfluidic channels
Creators: name: Wu, Jing
name: Day, Daniel
name: Gu, Min
Publisher: name: Swinburne
Year: 2024

description: We have successfully applied an optical tweezer for mapping the velocity profile in microfluidic channels. The velocity profiles for a straight and a u-shaped microfluidic channels were determined by direct measurement of the Stokes force.
A role for aquaporin-4 during induction of form deprivation myopia in chick
Creators: name: Goodyear, Melinda J.
name: Junghans, Barbara M.
name: Giummarra, Loretta
name: Murphy, Melanie J.
name: Crewther, David
name: Crewther, Sheila G.
Publisher: name: Swinburne
Year: 2024

description: Aquaporins (AQP) form a family of specialized water channels known to transport water across cell membranes and reduce osmotic gradients. The isoform AQP4 is highly expressed in the astroglia of the brain and Müller cells in the retina. In the brain, AQP4 play a role in the control of cerebral edema by shunting excess fluid into blood vessels and by upregulating during conditions of hyperosmolarity. Thus, on the basis of the hyperosmolarity seen across the retina and choroid of hatchling chickens made myopic by form deprivation (FD), We predicted an upregulation of retinal AQP4 expression during induction of myopia. Two-day-old hatchling chicks were monocularly form-deprived for 48, 72, or 96 h, and then after biometric assessment, the eyes of these animals and the normal controls of the same age were enucleated. Retinal tissue was prepared either for western blot analysis to show the presence of the AOP4 Protein in the chick retina or for immunolocalization using polyclonal AQP4 antibodies to determine regional distribution and intensity of labeling during the induction of form deprivation myopia (FDM). As expected, ultrasonography demonstrated that all post hatchling eyes showed rapid elongation with occluded eyes elongating faster than fellow eyes or normal controls and becoming progressively more myopic with the duration of visual deprivation. Western blot analyses revealed an approximately 30 kDa band immunoreactive for AQP4 protein and confirmed the presence of AQP4 in chicks. Immunohistochemical staining showed the greatest positive immunoreactivity for antibodies to AQP4 in the inner retina along the vitreoretinal interface, nerve fiver layer, ganglion cell layer, and inner plexiform layer in all animals. The control eyes showed relatively constant levels of AQP4 expression until day 5 after which the level appeared to decrease. By comparison, positive AQP4 immunoreactivity in the nerve fiber layer increased significantly over the first 48 h in form-deprived eyes and in fellow eyes and then decreased over the next 48 h but not to the level of expression in the normal untreated eyes. This is the first study to demonstrate the presence of AQP4 protein in the chick retina and to associate AQP4 expression in the inner retina with the initiation of form deprivation and the period of fastest axial elongation. This increased expression of AQP4 channels near the vitread border during the time of rapid growth suggests a role for AQP4 as a conduit for movement of retinal fluid into the vitreous in form-deprived chicks.
Retaining nursing students and novice nurses. The role of musculoskeletal symptoms and physical work factors
Creators: name: Kox, Jos
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 399999
subject: Other education not elsewhere classified
classificationCode: 420505
subject: Nursing workforce
classificationCode: 420599
subject: Nursing not elsewhere classified

description: Student and novice nurse attrition are of growing concern. Retaining nursing students and novice nurses is essential to maintain quality of care. It is, therefore, imperitive to understand the determinants and predictors that contribute to their dropout. The focus of this thesis is on the physical resilience of nursing students and novice nurses in order to contribute to the retention of this particular group of (student) nurses. This thesis is devided into three parts. In the first part, we explored the motives and determinants that contribute to dropout intention and actual dropout of student and novice nurses. The second part describes the determinants and predictors of dropout intention, actual dropout and musculoskeletal complaints in nursing students and novice nurses. In the third part, we focussed on the effectiveness and feasibility of preventive interventions with regard to physical resilience. This thesis contributes to the scientific knowledge on the motives and determinants of dropout of nursing students and novice nurses with focus on their physical resilience. lt provides practical recommendations for education and practice on how to improve the physical resilience of these target groups, in order to retain (student) nurses.
ASAPM - An agent-based framework for adaptive management of composite service lifecycle
Creators: name: Baruwal Chhetri, Mohan
name: Mueller, Ingo
name: Goh, Suk Keong
name: Kowalczyk, Ryszard
Publisher: name: Swinburne
Year: 2024

description: Agent technology is well positioned to address some of the key problems of Service-oriented Computing. It can work together with other technologies such as Web/Grid Services, Semantic Web, Process technologies, and Component Software to contribute to wide adoption of the Service-oriented Computing paradigm. This paper presents a generic agent-based framework which can be used as reference architecture for developing agent-based systems for composite service life-cycle management. The focus is on providing techniques and tools for the adaptive service agreement and process management in order to ensure collective functionality, end-to-end QoS, and adaptive provision of complex services.
Spatial and temporal dissociation of AQP4 and Kir4.1 expression during induction of refractive errors
Creators: name: Goodyear, Melinda J.
name: Crewther, Sheila G.
name: Murphy, Melanie J.
name: Giummarra, Loretta
name: Hazi, Agnes
name: Junghans, Barbara M.
name: Crewther, David
Publisher: name: Swinburne
Year: 2024

description: Purpose: Spatial co-localization of aquaporin water channels (AQP4) and inwardly rectifying potassium ion channels (Kir4.1) on the endfeet regions of glial cells has been suggested as the basis of functionally interrelated mechanisms of osmoregulation in brain edema. The aim of this study was to investigate the spatial and temporal changes in the expression of AQP4 and Kir4.1 channels in an avascular retina during the first week of the optical induction of refractive errors. Methods: Three-day-old hatchling chicks were randomly assigned to three groups and either did not wear lenses or were monocularly goggled with +/- 10D lenses for varying times up to 7 days before biometric assessment. Retinal tissue was prepared either for western blot analysis to show the presence of the AQP4 and Kir4.1 protein in the chick retina or for immunolocalization using AQP4 and Kir4.1 antibodies to determine the regional distribution and intensity of labeling during the induction of refractive errors. Results: As expected, ultrasonography demonstrated that all eyes showed rapid elongation post hatching. Negative lens-wearing eyes elongated faster than fellow eyes or normal non goggled eyes and became progressively more myopic with time post lensing. Positive lens-wearing eyes showed reduced ocular growth compared to normal controls and developed a hyperopic refraction. Quantitative immunohistochemistry revealed the upregulation of AQP4 channel expression on Muller cells in the retinal nerve fiber layer during the first 2 days of negative lens wear. Kir4.1 channel upregulation in the inner plexiform layer was only found on day 4 of positive lens wear during the development of refractive hyperopia. Conclusions: These results indicate that the expression of AQP4 and Kir4.1 channels on Muller cells is associated with the changes in ocular volume seen during the induction of refractive errors. However, the sites of greatest expression and the temporal pattern of the upregulation of AQP4 and Kir4.1 were dissimilar, indicating a dissociation of AQP4 and Kir4.1 function during refractive error development. Increased AQP4 expression in the nerve fiber layer is suggested to contribute to the rapid axial elongation and movement of fluid into the vitreous cavity in the presence of minus lenses; whereas, upregulation of Kir4.1 channels appears to play a role in limiting axial elongation in the presence of plus lenses.
Different temporal structure for form versus surface cortical color systems - Evidence from chromatic non-linear VEP
Creators: name: Crewther, David
name: Crewther, Sheila G.
Publisher: name: Swinburne
Year: 2024

description: Physiological studies of color processing have typically measured responses to spatially varying chromatic stimuli such as gratings, while psychophysical studies of color include color naming, color and light, as well as spatial and temporal chromatic sensitivities. This raises the question of whether we have one or several cortical color processing systems. Here we show from non-linear analysis of human visual evoked potentials (VEP) the presence of distinct and independent temporal signatures for form and surface color processing. Surface color stimuli produced most power in the second order Wiener kernel, indicative of a slowly recovering neural system, while chromatic form stimulation produced most power in the first order kernel (showing rapid recovery). We find end-spectral saturation-dependent signals, easily separable from achromatic signals for surface color stimuli. However physiological responses to form color stimuli, though varying somewhat with saturation, showed similar waveform components. Lastly, the spectral dependence of surface and form color VEP was different, with the surface color responses almost vanishing with yellow-grey isoluminant stimulation whereas the form color VEP shows robust recordable signals across all hues. Thus, surface and form colored stimuli engage different neural systems within cortex, pointing to the need to establish their relative contributions under the diverse chromatic stimulus conditions used in the literature.
Compositional learning of mutually recursive procedural systems
Creators: name: Frohme, Markus
name: Steffen, Bernhard
Publisher: name: TU Dortmund
Year: 2021
Subjects: subject: Active automata learning
subject: Procedural systems
subject: Context-free languages
subject: Visibly pushdown languages
subject: 004
subject: Kontextfreie Sprache
subject: Deterministischer endlicher Automat

description: This paper presents a compositional approach to active automata learning of Systems of Procedural Automata (SPAs), an extension of Deterministic Finite Automata (DFAs) to systems of DFAs that can mutually call each other. SPAs are of high practical relevance, as they allow one to efficiently learn intuitive recursive models of recursive programs after an easy instrumentation that makes calls and returns observable. Key to our approach is the simultaneous inference of individual DFAs for each of the involved procedures via expansion and projection: membership queries for the individual DFAs are expanded to membership queries of the entire SPA, and global counterexample traces are transformed into counterexamples for the DFAs of concerned procedures. This reduces the inference of SPAs to a simultaneous inference of the DFAs for the involved procedures for which we can utilize various existing regular learning algorithms. The inferred models are easy to understand and allow for an intuitive display of the procedural system under learning that reveals its recursive structure. We implemented the algorithm within the LearnLib framework in order to provide a ready-to-use tool for practical application which is publicly available on GitHub for experimentation.
description: International journal on software tools for technology transfer;Vol. 23. 2021, issue 4, pp 521-543
Infinitely Divisible Multivariate Distributions
Creators: name: Li, Catherine
Publisher: name: The University of Texas at Austin
Year: 2022
Subjects: Random variables
moment generating functions
infinitely divisible
gamma distribution
negative binomial distribution
bivariate
multivariate
Poisson distribution

description: Infinitely divisible random variables have distributions that can be written as sums of countably many independent and identical distributions, i.e. a random variable $X$ is infinitely divisible if X= ∑_(i=1)^n X_i =X_1+X_2+⋯+X_n for any n, where the X_i are independent and identically distributed. In terms of moment generating functions – functions with special properties that are unique to each distribution – X will have the property M_X (θ)=(M_(X_i ) (θ) )^n These kind of random variables are interesting to explore due to their broad application to many fields and concepts. In this thesis, I will look at an infinitely divisible bivariate gamma distribution studied in the 1969 paper “A Class of Infinitely Divisible Bivariate Gamma Distributions" by R. C. Griffiths. Throughout this paper, Griffiths obtains his conclusions by working with the moment generating function of the bivariate gamma, but does not mention how the moment generating function might arise from random variables. I will thus construct this bivariate gamma distribution through joint Poisson and gamma random variables. I will then extend this construction method to create two different infinitely divisible multivariate gamma distributions and an infinitely divisible negative binomial distribution.
Homocysteine as a potential biochemical marker for depression in elderly stroke survivors
Creators: name: Pascoe, Michaela C.
name: Crewther, Sheila G.
name: Carey, Leeanne M.
name: Noonan, Kate
name: Crewther, David
name: Linden, Thomas
Publisher: name: Swinburne
Year: 2024

description: Background: Elderly stroke survivors have been reported to be at risk of malnutrition and depression. Vitamin B-related metabolites such as methylmalonic acid and homocysteine have been implicated in depression. Objective: We conducted a study exploring the relationship between homocysteine and post-stroke depression. Design: Three methodologies were used: Observational cohort study of elderly Swedish patients (n = 149) 1.5 years post-stroke, assessed using Diagnostic and Statistical Manual of Mental Disorders, Montgomery Åsberg Depression Rating Scale and serum blood levels of methylmalonic acid and homocysteine. Results: Homocysteine significantly correlated with depressive symptomatology in stroke survivors (β=0.18*). Individuals with abnormal levels of methylmalonic acid and homocysteine were almost twice more likely to show depressive symptomatology than those with normal levels (depressive symptoms 22%; no depressive symptoms 12%). Comparison of methylmalonic acid and homocysteine levels with literature data showed fewer stroke survivors had vitamin deficiency than did reference individuals (normal range 66%; elevated 34%). Conclusions: Homocysteine is significantly associated with depressive symptomatology in elderly Swedish stroke survivors.
Development of model parameters for early-age properties and crack-width prediction of slag concretes
Creators: name: Aiy, T.
name: Sanjayan, Jay
Publisher: name: Swinburne
Year: 2024

description: A study to develop the parameters of the models for predicting the deformation characteristics of normal-strength concrete incorporating slag-blended cements at early age is presented in this paper. By comparing with the previous experimental results, it was found that the basic shrinkage and creep factor decreased significantly owing to the expansion of slag concrete during the first week of moist curing. When utilising the developed models for estimating the crack width, it was found that the initial crack width of concrete subjected to restraint drying shrinkage is reduced if the slag content level increased up to 50 and 65% in the concrete mixture. Further, slag concrete tends to have less crack width and lower number of cracks in the long term compared with that with no slag.
SMURF: Supporting multi-tenancy using re-aspects framework
Creators: name: Almorsy, Mohamed
name: Grundy, John
name: Ibrahim, Amani S.
Publisher: name: Swinburne
Year: 2024

description: Software-as-a-service multi-tenancy helps service providers to cut cost, improve resource utilization, and reduce service customization and maintenance time as the tenants share the same service instance. However, existing large-scale business applications inherently do not support multi-tenancy. This hinders these applications' vendors from adopting the cloud model. Thus reengineering such applications to support multi-tenancy has become a key requirement. Reengineering such applications to support multi-tenancy is a complex and challenging task as it requires a deep understanding of the given application and almost all system modules need to be revisited. In this paper we introduce SMURF, Supporting Multi-tenancy Using Reengineering Aspects 'Re-Aspect' Framework, to help service providers reengineering their legacy applications to support multi-tenancy. SMURF is based on our new re-aspects concept where a given system modification to disable, modify, replace or inject code is encapsulated in a re-aspect. SMURF realizes given system modifications (captured as re-aspects) by automating both change impact analysis and change propagation processes. We analyze the SaaS multi-tenancy pattern, discuss the set of requirements to migrate a single-tenant application to support multi-tenancy, describe SMURF approach, architecture and implementation details, and experimental results of SMURF given a set of open source web applications.
Assessing the Sustainability of an Aluminum Roofing Sheet Corrugating Machine by Reliability Centered Maintenance and Cost Reduction Technique
Creators: name: S. L. Bani, H. U. Nwos
Publisher: name: Zenodo
Year: 2024

description: In any organized manufacturing firm, maintenance of the operational machines or equipment is prominent since adequate maintenance prevents the system from unnecessary breakdown, hence promotes productivity. This study thereforeassessed the capability and sustainability of an aluminum roofing sheets corrugating machine by reliability centered maintenance cost approach ina manufacturing firm in Port Harcourt. For data acquisition, breakdown and maintenance records of selected components of the machine was collected from the company. Exponential distribution was used for analysis of failure trend, reliability, and mean time between failures of the components. Maintenance cost was also analyzed. Results shows that the minimum rate of failure of roll bearingswas 0.00050403yr-1 in 2014, while the maximum was 0.00996678 yr-1in 2020. The maximum reliability of the system due to cutting device for the period investigated was 0.367. The maximum reliability of the corrugating machine from the perspective of electric motor was 0.3678. Similarly, the minimum mean time between failures of the machine components were: rolls 100 hours; cutting device 151 hours; de-coiler121hours; electric motor 151hours. The maintenance cost of the system for the period investigated follows: 5,749,421.21 Naira, 3,795,238.92Naira, and 4, 783,796.05 Naira for 2016, 2017 and 2018, respectively; 3,844,911.48 Naira, 4,637,049.52 Naira and 6,582,397.53 Naira for 2019,2020 and 2021, respectively. The proposed technique enhances a reduction of maintenance cost by 3.6%.
Checking multivalued dependencies in XML
Creators: name: Liu, Jixue
name: Vincent, Millist
name: Liu, Chengfei
name: Mohania, Mukesh
Publisher: name: Swinburne
Year: 2024

description: Recently, the issues of how to define functional dependencies (XFDs) and multivalued dependencies (XMVDs) in XML have been investigated. In this paper we consider the problem of checking the satisfaction of a set of XMVDs in an XML document. We present an algorithm using extensible hashing to check whether an XML document satisfies a given set of XMVDs. The performance of the algorithm is shown to be linear in relation to the number of tuples of the XML document, a measure which is related to, but not the same as, the size of the XML document.
New method to assess mitophagy flux by flow cytometry
Creators: name: Mauro-Lizcano, Marta
name: Esteban-Martínez, Lorena
name: Seco, Esther
name: Serrano-Puebla, Ana
name: Garcia-Ledo, Lucia
name: Figueiredo-Pereira, Cláudia
name: Vieira, Helena L A
name: Boya, Patricia
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Microbiology
subject: FOS: Biological sciences
subject: Biochemistry
subject: Biophysics

description: Mitochondrial autophagy, also known as mitophagy, is an autophagosome-based mitochondrial degradation process that eliminates unwanted or damaged mitochondria after cell stress. Most studies dealing with mitophagy rely on the analysis by fluorescence microscopy of mitochondrial-autophagosome colocalization. However, given the fundamental role of mitophagy in the physiology and pathology of organisms, there is an urgent need for novel quantitative methods with which to study this process. Here, we describe a flow cytometry-based approach to determine mitophagy by using MitoTracker Deep Red, a widely used mitochondria-selective probe. Used in combination with selective inhibitors it may allow for the determination of mitophagy flux. Here, we test the validity of the use of this method in cell lines and in primary cell and tissue cultures.
Intramolecular interactions of L-phenylalanine revealed by inner shell chemical shift
Creators: name: Ganesan, Aravindhan
name: Wang, Feng
Publisher: name: Swinburne
Year: 2024

description: Intramolecular interactions of the functional groups, carboxylic acid, amino, and phenyl in L-phenylalanine have been revealed through inner shell chemical shift. The chemical shift and electronic structures are studied using its derivatives, 2-phenethylamine (PEA) and 3-phenylpropionic acid (PPA), through substitutions of the functional groups on the chiral carbon C-alpha, i.e., carboxylic acid (-COOH) and amino (-NH2) groups. Inner shell ionization spectra of L-phenylalanine are simulated using density functional theory based B3LYP/TZVP and LB94/et-pVQZ models, which achieve excellent agreement with the most recently available synchrotron sourced x-ray photoemission spectroscopy of L-phenylalanine (Elettra, Italy). The present study reveals insight into behavior of the peptide bond (CO-NH) through chemical shift of the C-1-C-alpha-C-beta(-C-gamma) chain and intramolecular interactions with phenyl. It is found that the chemical shift of the carbonyl C-1(=O) site exhibits an apparently redshift (smaller energy) when interacting with the phenyl aromatic group. Removal of the amino group (-NH2) from L-phenylalanine (which forms PPA) brings this energy on C-1 close to that in L-alanine (delta<0.01 eV). Chemical environment of C-alpha and C-beta exhibits more significant differences in L-alanine than in the aromatic species, indicating that the phenyl group indeed affects the peptide bond in the amino acid fragment. No direct evidences are found that the carbonyl acid and amino group interact with the phenyl ring through conventional hydrogen bonds.
An object oriented approach towards dynamic data flow analysis
Creators: name: Cain, Andrew
name: Chen, Tsong
name: Grant, Doug
name: Kuo, Fei-Ching
name: Schneider, Jean-Guy
Publisher: name: Swinburne
Year: 2024

description: Dynamic data flow analysis is a testing technique that has been successfully used for many procedural programming languages. However, for Object-Oriented (OO) programs, previous investigations have still followed a data-oriented approach to keep track of the state information for various data elements. This paper proposes an OO approach to perform dynamic data flow analysis for OO programs. In this approach, a meta-model of an OO programpsilas runtime structure is constructed to manage the data flow analysis for the program. An implementation of the model for the Java language is presented, illustrating the practicality and effectiveness of this innovative approach.
Dynamic test profiles in adaptive random testing: A case study
Creators: name: Liu, Huai
name: Kuo, Fei-Ching
name: Chen, Tsong
Publisher: name: Swinburne
Year: 2024

description: Random testing (RT) is a basic software testing method. When used to detect software failures, RT usually generates random test cases according to a uniform distribution. Adaptive random testing (ART) is an innovative approach to enhancing the failure-detection capability of RT. Most ART algorithms are composed of two independent processes, namely the candidate generation process and the test case identification process. In these ART algorithms, some program inputs are first randomly generated as the test case candidates; then test cases are identified from these candidates in order to ensure an even spread of test cases across the input domain. Most previous studies on ART focused on the enhancement of the test case identification process, while using the uniform distribution in the candidate generation process. A recent study has shown that using a dynamic test profile in the candidate generation process can also improve the failure-detection capability of ART. In this paper, we develop various test profiles and integrate them with the test case identification process of a particular ART algorithm, namely fixed size-candidate-set ART. It is observed that all these test profiles can significantly improve the failure-detection capability of ART.
An innovative approach to randomising quasi-random sequences and its application into software testing
Creators: name: Liu, Huai
name: Chen, Tsong
Publisher: name: Swinburne
Year: 2024

description: Quasi-random sequences, which can evenly spread points across a hypercube, have been widely used in various areas. Recently, quasi-random testing technique, which makes use of quasi-random sequences to generate test cases, was proposed, and it normally has a higher failure-detection capability than pure random testing. However, there exist only a few distinct quasi-random sequences in the literature, and all these sequences are deterministic rather than random. Therefore, the applicability of quasi-random sequences in testing is restricted. In this paper, we propose a new approach to randomising quasi-random sequences. Out approach can generate many distinct randomised quasi-random sequences that have even distributions of points. The experimental results also show that these sequences can significantly enhance the effectiveness of random testing.
Advances in research on nickel production through the caron process
Creators: name: Rhamdhani, Akbar
name: Chen, Jinjun
name: Hidayat, T.
name: Jak, E.
name: Hayes, P. C.
Publisher: name: Swinburne
Year: 2024

description: New environmental and chemical policy regulations require further optimisation of current nickel production processes. This paper outlines recent fundamental research in support of improvements in nickel production process through the Caron Process. The research focuses on two major areas: (i) reduction roasting of nickel laterite, and (ii) reduction of basic nickel carbonate (BNC) and NiO to nickel. Nickel in laterite is associated with Fe-rich goethite and serpentine/olivine particles. Results indicate that the nickel recoveries from the limonite ores correspond closely to values predicted by thermodynamic modelling; nickel recoveries from serpentine ores are however significantly lower than these chemical equilibrium values. The nickel recovery from serpentine/olivine appears to be higher for particles with Mg to Fe mol ratio of lower than 8. In relation to the reduction of BNC and NiO, the change of phase, product surface, internal microstructures taking place during reduction/oxidation of BNC at 110oC to 900oC; as well as the kinetics and microstructure transformation mechanism during reduction of synthetic NiO at 400oC to 1000oC have been studied. A clear link has been established between the rates of reduction, the nickel product morphology, and the reaction mechanisms occurring at the Ni-NiO interface. A change in the reduction behaviour was observed between 600 and 800oC depending on the hydrogen partial pressures and reduction time. The phenomena affecting the final-product microstructure were identified as follows: (1) chemical changes, i.e. decomposition, reduction and oxidation reactions; (2) NiO and Ni recrystallisation and grain growth; (3) NiO and Ni sintering and densification; and (4) agglomeration of the NiO and Ni particles.
Statistical analysis of structural failures of water pipes
Creators: name: Dehghan, A.
name: McManus, Kerry
name: Gad, Emad
Publisher: name: Swinburne
Year: 2024

description: Statistical analysis and prediction of failure rates of water distribution pipes are usually performed using parametric lifetime models. In this paper, a new probabilistic measure for the failure rate, called the 'likelihood of number of failures', is defined and formulated for cases where the pipe lifetimes follow parametric models. The resulting theoretical failure rates are time-invariant and, therefore, the parametric models would be useful only if the failure rates of water distribution pipes are stationary random processes. This paper then examines the stationarity of pipe failure rates in practice. For the water pipes in the western district of Melbourne (Australia), the failure rates are empirically calculated using a 4-year failure history, and it is observed that the distribution of empirical failure rates varies with time. In order to explain these variations, the pattern of rainfall in the region is compared with the pattern of failure rate variations, and in 70% of the times the two patterns are observed to be consistent. Two approaches are proposed to tackle the time-varying nature of pipe failure rate processes: regular updating of the parameters of lifetime models or developing a non-parametric technique for modelling of pipe failure rates.
An ARMA(1,1) prediction model of first person shooter game traffic
Creators: name: Branch, Philip
name: Cricenti, Tony
name: Armitage, Grenville
Publisher: name: Swinburne
Year: 2024

description: Modeling traffic generated by Internet-based multiplayer computer games has attracted a great deal of attention in the past few years. In part this has been driven by a need to simulate correctly the network impact of highly interactive online game genres such as the first person shooter (FPS). Packet size distributions and autocovariance models are important elements in the creation of realistic traffic generators for network simulators. In this paper we present simple techniques for creating representative models for N-player FPS games based on empirically measured traffic of 2- and 3-player games. The models capture the packet size distribution as well as the time series behaviour of game traffic. We illustrate the likely generality of our approach using data from seven FPS games that have been popular over the past nine years: Half-Life, Half-Life Counterstrike, Half-Life 2, Half-Life 2 Counterstrike, Quake III Arena, Quake 4 and Wolfenstein Enemy Territory.
Synthesis of New Acyclic Schiff Base Oxovanadium(IV) Complexes and Their Electrochemical, Catecholase, and Antimicrobial Studies of Minimum Inhibitory Concentration
Creators: name: A. Vijayaraj
name: R. Prabu
name: R. Suresh
name: N. Mathivanan
name: V. Narayanan
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Cell Biology
subject: Microbiology
subject: FOS: Biological sciences
subject: Biochemistry

description: Catalytically active complexes containing [VO(IV)L] were synthesized by using Schiff base ligands L1–5 and vanadyl sulfate. Ligands L1–5 were obtained by the condensation of 5-methylsalicylaldehyde with diethylene triamine (L1), tris(2-aminoethyl)amine (L2), triethylene tetramine (L3), N,N-bis(3-aminopropyl)ethylenediamine (L4) and N,N- bis(aminopropyl) piperazine (L5). All the complexes were characterized by elemental and spectral analysis. ESR spectra for the mononuclear [VO(IV)L] complexes show eight lines, square pyramidal geometry. Room temperature magnetic moment for the complexes was around 1.73 B.M. Electrochemical and catalytic studies of the complexes were compared on the basis of chain length of the imine compartment. All the [VO(IV)L1–5] complexes were screened antibacterial activity of MIC.
Covert channels in multiplayer first person shooter online games
Creators: name: Zander, Sebastian
name: Armitage, Grenville
name: Branch, Philip
Publisher: name: Swinburne
Year: 2024

description: Covert channels aim to hide the existence of communication between two or more parties. Such channels typically utilise pre-existing (overt) data transmissions to carry hidden messages. Internet-based covert channels often encode new information into unused (or loosely specified) IP packet header fields, or the time intervals between IP packet arrivals. We propose a novel covert channel embedded within the traffic of multiplayer, first person shooter online games. We encode covert bits as slight, yet continuous, variations of a player's character's movements. Movement information is propagated to all clients attached to a given game server, yet the channel remains covert so long as the variations are visually imperceptible to the human players. A modified version of Quake III Arena is used to demonstrate our concept. We empirically analyse the covert channel's bit rate, and compare the statistical characteristics of unmodified game traffic with those of game traffic carrying covert information.
"KULTEGIN" BITIKTОSHI YОDGОRLIKLАRIDА QО'LLАNILGАN ОNОMАSTIK BIRLIKLАR
Creators: name: Ro'ziyev, Qahramon
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqolada “Kultegin” bitiktoshining lingvostatistik tahlili amalga oshirilgan. Onomastik birliklar tahlil qilinib, antroponim, zoonimlarning miqdoriy ma’lumotlari berilgan. Shuningdek, bitiktoshda ishlatilgan inson tana a’zolari va qurol-aslaha nomlari izohlangan.