cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
SaxFDM-Fokusprojekt PUDEL bei der Digital Kitchen vom 16.02.23
Creators: name: Becker, Anja
name: Graiff, Cecilia
Publisher: name: Zenodo
Year: 2023
Subjects: SaxFDM
Digital Kitchen
Fokusprojekt

description: Bei der Digital Kitchen am 16.02.2023 im Rahmen der Love Data Week hat das "SaxFDM-Fokusprojekt: Publikationsdienst für wissenschaftliche Datenmodelle und Vokabulare" (PUDEL) den aktuellen Projektstand präsentiert und einen Ausblick in die Zukunft gewährt.
Germanen willkommen! Von Barbaren und dem Mittelalter
Creators: name: Lubich, Gerhard
Publisher: name: G. Lubich, Germanen willkommen! Von Barbaren und dem Mittelalter, «Public history weekly», 2, 2014, n. 17
Year: 2014

description: Germanen oder die Beschäftigung mit ihnen ist nichts, was man unmittelbar mit zeitgenössischen Anforderungen an Lehre in Verbindung bringt. Im Gegenteil scheint der Weg in unaufgeklärte Mythenbildung, okkulten Romantizismus und Antimodernismus vorprogrammiert. Zeit für einen Epochenwandel.
BOSSINF STB
Creators: By- og Boligministeriet
Erhvervs- og Boligstyrelsen
Socialministeriet
Velfærdsministeriet
Indenrigs- og Socialministeriet
Publisher: name: Rigsarkivet
Year: 2025

description: BOSSINF-STB skal understøtte sagsbehandlingen i forbindelse med statens støtte primært til nybyggeri af almene boliger i Danmark. Der SKAL indberettes i systemets skemaer A, B og C, når der søges om ydelsesstøtte eller servicearealtilskud. Systemet sikrer fx, at byggeriet overholder lovmæssige bestemmelser for anskaffelsessummer (dvs. at der bygges inden for et maksimumbeløb), at realkreditbelåningen overholder gældende lov, og at der ikke kan foretages overbelåning. Systemet danner grundlag for, at Kongeriget Danmarks Hypotekbank (1998), Finansstyrelsen (1999-2002, Økonomistyrelsen (2003-2010) kan udbetale ydelsesstøtte og servicearealtilskud.
title: Stellungnahme zum Antrag auf strategische Erweiterung des Leibniz-Instituts für Zoo- und Wildtierforschung (IZW), Berlin, großer strategischer Sondertatbestand im Rahmen der Ausführungsvereinbarung WGL
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2022
Subjects: Evaluation
Leibniz-Verfahren
Forschungseinrichtungen
Wildtierforschung
Verhaltensökologie
Evolutionsgenetik
Reproduktionsbiologie

description: Das Leibniz-Institut für Zoo- und Wildtierforschung (IZW) will die Anpassungsfähigkeit von Wildtieren im Kontext des globalen Wandels verstehen und zum Erhalt von gesunden Wildtierbeständen beitragen. Dazu untersucht es die Vielfalt der Lebensweisen, die Mechanismen evolutionärer Anpassungen und die Anpassungsgrenzen inklusive Krankheiten von Wildtieren sowie ihre Wechselbeziehungen mit Mensch und Umwelt. Der Erweiterungsantrag des IZW zielt auf die Einführung von aktuellen Technologien ab, die die Wildtierforschung des Instituts auf ein neues Niveau bringen sollen. Hierfür ist die Anschaffung von Forschungsgeräten der neuesten Generation sowie die Einrichtung von Stellen für Personal erforderlich, das diese Technologien anwenden kann. Der Wissenschaftsrat bewertet den Antrag als "sehr gut". Der mit der Erweiterung verbundene Methoden- und Technologienaufwuchs würde die Forschung des Instituts auf ein neues Niveau bringen und sein Forschungsspektrum deutlich verbreitern, so dass das IZW dadurch ausgezeichnete Voraussetzungen hätte, seine Position in der internationalen Spitzenforschung halten und ausbauen zu können.
Magnetoelectric coupling tuned by competing anisotropies in Mn$_{1-x}$Ni$_{x}$TiO$_3$
Creators: name: Chi, Songxue
name: Ye, Feng
name: Zhou, H. D.
name: Choi, E. S.
name: Hwang, J.
name: Cao, Huibo
name: Fernandez-Baca, Jaime A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: A flop of electric polarization from $P$$\parallel$$c$ ($P_c$) to $P$$\parallel$$a$ ($P_a$) is observed in MnTiO$_3$ as a spin flop transition is triggered by a $c$-axis magnetic field, $H_{\|c}$=7 T. The critical magnetic field $H_{\|c}$ for $P_a$ is significantly reduced in Mn$_{1-x}$Ni$_x$TiO$_3$ (x=0.33). $P_a$ and $P_c$ have been observed with both $H_{\|c}$ and $H_{\|a}$. Neutron diffraction measurements revealed similar magnetic arrangements for the two compositions where the ordered spins couple antiferromagnetically with their nearest intra- and inter-planar neighbors. In the x=0.33 system, the uniaxial and planar anisotropies of Mn$^{2+}$ and Ni$^{2+}$ compete and give rise to a spin reorientation transition at $T_R$. A magnetic field, $H_{\|c}$, aligns the spins along $c$ for $T_R$$
description: 7 pages, 7 figures
title: Clinical approach to administrate contrast medium dose as the basis for lean body weight (LBW) using three dimensions computed tomography imaging (3DCT)
Creators: name: Ishida, Wataru
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Contrast agents
subject: Liver
subject: CT
subject: Computer Applications-3D
subject: Contrast agent-other
subject: Cancer
subject: Metastases

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: ・Back ground Results of previous studies have shown that it was appropriate to determine the contrast material dose based on the patient's total body weight (TBW) in contrast-enhanced CT examination [1]. However, the TBW method results in overdose...
title: Stellungnahme zum Antrag auf strategische Erweiterung der Senckenberg Gesellschaft für Naturforschung (SGN), Frankfurt am Main, großer strategischer Sondertatbestand im Rahmen der Ausführungsvereinbarung WGL
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2022
Subjects: Evaluation
Leibniz-Verfahren
Forschungsinfrastrukturen
Wissenschaft und Gesellschaft
Biodiversitätsfoschung
Erdsystemforschung
Geowissenschaften

description: Die Senckenberg Gesellschaft für Naturforschung (SGN), Frankfurt am Main, fokussiert ihre integrative Naturforschung auf den Wandel und den Verlust von Biodiversität. Grundgedanke des Erweiterungsvorhabens der SGN ist die Nutzung und digitale Inwertsetzung ihrer herausragenden wissenschaftlichen Sammlungen für die Erforschung der Biodiversität, um so zu einem verbesserten Verständnis des Erdsystems zu gelangen. Die beantragte Erweiterung gründet auf dem Konzept eines integrierten Forschungsmuseums mit den drei Modulen Collectomics, Biodiversity Genomics und Solutions Labs. Im Jahr 1817 auf Initiative von Frankfurter Bürgerinnen und Bürgern gegründet, blickt Senckenberg auf eine lange Tradition als Bürgergesellschaft zurück. Heute zählt die Senckenberg Gesellschaft fast siebentausend Mitglieder.
Global-scale hybrid simulation of cusp precipitating ions associated with magnetopause reconnection under southward IMF
Creators: name: Tan, B
name: Lin, Y
name: Perez, J
name: Wang, X
Publisher: name: Auburn University
Year: 2012

description: With a 3-D global-scale hybrid simulation model, we investigate the energy spectra of cusp precipitating ions and issues associated with magnetopause reconnection under a southward IMF. Both the spatial and temporal energy spectra of cusp precipitating ions are computed by tracing trajectories of the transmitted magnetosheath ions. The spatial spectrum shows a dispersive feature consistent with satellite observations, with higher energy particles at lower latitudes and lower energy particles at higher latitudes. The simulation reveals (1) how and where particles are transmitted from the solar wind into the magnetosphere via direct magnetic reconnection on the dayside; (2) how the features of the spectra are related to ongoing magnetic FTEs; and (3) how the motion of the cusp, particularly the latitudinal variation of the open/closed field line boundary, is correlated with the dayside reconnection and reflected in the energy flux spectra of the precipitating ions as a function of time.
title: What the radiologist needs to know about normal findings and complications of kidney transplant
Creators: name: Tawk, Sammy
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Transplantation
subject: Outcomes
subject: Diagnostic procedure
subject: Ultrasound
subject: MR
subject: CT
subject: Vascular
subject: Kidney
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Recognize the normal appearance of a kidney transplant in the early and late phases. Discuss the vascular and non-vascular complications of renal transplantation, occurring in the early and late phases. Review the role of interventional radiology in...
Evaluatie van de cultuursensitieve leefstijlinterventie SimpelFit! - Onderzoeksprotocol
Creators: name: Gündüz, M.
name: Mul, S.
name: Streppel, M.T.
name: Weijs, P.J.M.
name: Fukkink, R.G.
name: Booij, Y.S.
Publisher: name: University of Amsterdam / Amsterdam University of Applied Sciences
Year: 2023
Subjects: Health Sciences

description: Onderzoeksprotocol voor het onderzoeksproject "Evaluatie van de cultuursensitieve leefstijlinterventie SimpelFit! - Onderzoeksprotocol"
Macroscopic Modeling of Fingerpad Friction Under Electroadhesion: Possibilities and Limitations
Creators: name: Heß, Markus
name: Forsbach, Fabian
Publisher: name: Technische Universität Berlin
Year: 2020
Subjects: subject: 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten
subject: friction
subject: adhesion
subject: electrovibration
subject: surface haptics
subject: finite element method
subject: FEM
subject: compliance method
subject: hyperelastic material

description: Electrovibration is one of the key technologies in surface haptics. By inducing controlled electrostatic forces, the friction within a sliding contact between the human finger and a capacitive screen is modulated, which in turn gives effective tactile feedback to the user. Such powerful haptic displays can be built into mobile phones, tablets, navigation devices, games consoles and many other devices of consumer electronics. However, due to the layered structure and complex material of human skin, the underlying contact mechanical processes have not yet been fully understood. This work provides new continuum-based approaches to macroscopic modeling of the electro-adhesive frictional contact. A solution of pure normal contact between a human finger and a rigid, smooth plane under electroadhesion is derived by applying Shull's compliance method in the extended regime of large deformations. Based on these results and assuming pressure-controlled friction, a model for the sliding electro-adhesive contact is developed, which adequately predicts the friction force and coefficient of friction over the whole range of relevant voltages and applied normal forces. The experimentally observed area reduction caused by the tangential force is incorporated in a more empirical than profound contact mechanical way. This effect is studied with the help of a two-dimensional finite element model of the fingertip, assuming non-linear elastic material for the skin tissue. Although the simulations are restricted to non-adhesive tangential contacts, they show a significant reduction of the contact area, which is caused by large deformations of the non-linear elastic material around the distal phalanx. This result indicates that adhesion is only of secondary importance for the area reduction.
Supplementary information from Mapping the mental space of emotional concepts through kinematic measures of decision uncertainty
Creators: name: Barca, Laura
name: Candidi, Matteo
name: Lancia, Gian Luca
name: Maglianella, Valerio
name: Pezzulo, Giovanni
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology

description: Emotional concepts and their mental representations have been extensively studied. Yet, some ecologically relevant aspects, such as how they are processed in ambiguous contexts (e.g., in relation to other emotional stimuli that share similar characteristics), are incompletely known. We employed a similarity judgement of emotional concepts and manipulated the contextual congruency of the responses along the two main affective dimensions of hedonic valence and physiological activation, respectively. Behavioural and kinematics (mouse-tracking) measures were combined to gather a novel ‘similarity index’ between emotional concepts, to derive topographical maps of their mental representations. Self-report (interoceptive sensibility, positive–negative affectivity, depression) and physiological measures (heart rate variability, HRV) have been collected to explore their possible association with emotional conceptual representation. Results indicate that emotional concepts typically associated with low arousal profit by contextual congruency, with faster responses and reduced uncertainty when contextual ambiguity decreases. The emotional maps recreate two almost orthogonal axes of valence and arousal, and the similarity measure captures the smooth boundaries between emotions. The emotional map of a subgroup of individuals with low positive affectivity reveals a narrower conceptual distribution, with variations in positive emotions and in individuals with reduced arousal (such as those individuals with reduced HRV). Our work introduces a novel methodology to study emotional conceptual representations, bringing the behavioural dynamics of decision-making processes and choice uncertainty into the affective domain.This article is part of the theme issue ‘Concepts in interaction: social engagement and inner experiences’.
title: RECIL vs. Lugano classificaton: Advantages and disadvantages.
Creators: name: Jaimes Niño, Sara
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Lymphoma
subject: Education and training
subject: Developmental disease
subject: Staging
subject: Outcomes analysis
subject: Comparative studies
subject: PET-CT
subject: MR
subject: CT
subject: Lymph nodes
subject: Haematologic
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Over the years, multiple measurement scales have been developed to evaluate the response to treatment in patients with lymphoma. The last scales developed are: Lugano (2014) and RECIL (2016) (Fig. 2) classifications. Throughout this work we...
title: Beyond the bones: clinically significant abnormal extra-osseous uptake on technetium-99m methylene diphosphonate (MDP) whole body bone scintigraphy (WBS).
Creators: name: McGill, Maria
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Diagnostic procedure
subject: Nuclear medicine conventional
subject: Nuclear medicine
subject: Metabolic disorders
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Provide examples where clinically significant abnormal extra-osseous uptake on technetium-99m methylene diphosphonate (MDP) whole body bone scintigraphy (WBS) was demonstrated. Review the classification, pathogenesis and radiological appearances of...
Reduced Mitochondrial Respiration in Hybrid Asexual Lizards
Creators: name: Klabacka, Randy
name: Parry, Hailey
name: Yap, Kang Nian
name: Cook, Ryan
name: Herron, Victoria
name: Horne, Miles
name: Wolak, Matthew
name: Maldonado, Jose
name: Fujita, Matthew
name: Kavazis, Andreas
name: Oaks, Jamie
name: Schwartz, Tonia
Publisher: name: University of Chicago Press
Year: 2022
Subjects: parthenogenesis
asexuality
hybridization
mitochondria
endurance
variability

description: The scarcity of asexual reproduction in vertebrates alludes to an inherent cost. Several groups of asexual vertebrates exhibit lower endurance capacity (a trait predominantly sourced by mitochondrial respiration) compared with congeneric sexual species. Here we measure endurance capacity in five species of Aspidoscelis lizards and examine mitochondrial respiration between sexual and asexual species using mitochondrial respirometry. Our results show reduced endurance capacity, reduced mitochondrial respiration, and reduced phenotypic variability in asexual species compared with parental sexual species, along with a positive relationship between endurance capacity and mitochondrial respiration. Results of lower endurance capacity and lower mitochondrial respiration in asexual Aspidoscelis are consistent with hypotheses involving mitonuclear incompatibility.
title: Stellungnahme zum Antrag auf strategische Erweiterung des Römisch-Germanischen Zentralmuseums (RGZM), Mainz, durch Integration des Zentrums für Baltische und Skandinavische Archäologie (ZBSA), Schleswig, großer strategischer Sondertatbestand im Rahmen der Ausführungsvereinbarung WGL
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2022
Subjects: Evaluation
Leibniz-Verfahren
Archäologie
Forschungsmuseen
Frühgeschichte
Urgeschichte
Landesmuseen

description: Das RGZM ist ein 1852 auf Beschluss der deutschen Geschichts- und Altertumsvereine gegründetes Forschungsinstitut und -museum, welches heute als Stiftung des öffentlichen Rechts vom Land Rheinland-Pfalz und der Stadt Mainz getragen wird. Das Erweiterungsvorhaben des RGZM zielt auf die Integration des 2008 in Schleswig gegründeten ZBSA, wodurch die institutionellen Voraussetzungen für die Erforschung gesellschaftlicher Wandlungsprozesse über sehr lange Zeiträume hinweg geschaffen werden sollen. Der Wissenschaftsrat bewertet insbesondere die bereits weit fortgeschrittene Verzahnung der Forschungsprogramme der Einrichtungen sehr positiv. Die gewählten Themenfelder eignen sich ausgezeichnet, um die aus den bisherigen Forschungen des RGZM und des ZBSA gewonnenen Erkenntnisse zusammenzuführen und im engen Austausch weiterzuentwickeln.
Pairing-induced speedup of nuclear spontaneous fission
Creators: name: Sadhukhan, Jhilam
name: Dobaczewski, J.
name: Nazarewicz, W.
name: Sheikh, J. A.
name: Baran, A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Collective inertia is strongly influenced at the level crossing at which quantum system changes diabatically its microscopic configuration. Pairing correlations tend to make the large-amplitude nuclear collective motion more adiabatic by reducing the effect of those configuration changes. Competition between pairing and level crossing is thus expected to have a profound impact on spontaneous fission lifetimes. To elucidate the role of nucleonic pairing on spontaneous fission, we study the dynamic fission trajectories of $^{264}$Fm and $^{240}$Pu using the state-of-the-art self-consistent framework. We employ the superfluid nuclear density functional theory with the Skyrme energy density functional SkM$^*$ and a density-dependent pairing interaction. Along with shape variables, proton and neutron pairing correlations are taken as collective coordinates. The collective inertia tensor is calculated within the nonperturbative cranking approximation. The fission paths are obtained by using the least action principle in a four-dimensional collective space of shape and pairing coordinates. Pairing correlations are enhanced along the minimum-action fission path. For the symmetric fission of $^{264}$Fm, where the effect of triaxiality on the fission barrier is large, the geometry of fission pathway in the space of shape degrees of freedom is weakly impacted by pairing. This is not the case for $^{240}$Pu where pairing fluctuations restore the axial symmetry of the dynamic fission trajectory. The minimum-action fission path is strongly impacted by nucleonic pairing. In some cases, the dynamical coupling between shape and pairing degrees of freedom can lead to a dramatic departure from the static picture. Consequently, in the dynamical description of nuclear fission, particle-particle correlations should be considered on the same footing as those associated with shape degrees of freedom.
description: Submitted to PRC
De-novo collateral formation following acute myocardial infarction: Dependence on CCR2+ bone marrow cells
Creators: name: Zhang, Hua
name: Faber, James E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Wide variation exists in the extent (number and diameter) of native pre-existing collaterals in tissues of different strains of mice, with supportive indirect evidence recently appearing for humans. This variation is a major determinant of the wide variation in severity of tissue injury in occlusive vascular disease. Whether such genetic-dependent variation also exists in the heart is unknown because no model exists for study of mouse coronary collaterals. Also owing to methodological limitations, it is not known if ischemia can induce new coronary collaterals to form (“neo-collaterals”) versus remodeling of pre-existing ones. The present study sought to develop a model to study coronary collaterals in mice, determine whether neo-collateral formation occurs, and investigate the responsible mechanisms. Four strains with known rank-ordered differences in collateral extent in brain and skeletal muscle were studied: C57BLKS>C57BL/6>A/J>BALB/c. Unexpectedly, these and 5 additional strains lacked native coronary collaterals. However after ligation, neo-collaterals formed rapidly within 1-to-2 days, reaching their maximum extent in ≤ 7 days. Rank-order for neo-collateral formation differed from the above: C57BL/6>BALB/c>C57BLKS>A/J. Collateral network conductance, infarct volume−1, and contractile function followed this same rank-order. Neo-collateral formation and collateral conductance were reduced and infarct volume increased in MCP1−/− and CCR2−/− mice. Bone-marrow transplant rescued collateral formation in CCR2−/− mice. Involvement of fractalkine→CX3CR1 signaling and endothelial cell proliferation were also identified. This study introduces a model for investigating the coronary collateral circulation in mice, demonstrates that neocollaterals form rapidly after coronary occlusion, and finds that MCP→CCR2-mediated recruitment of myeloid cells is required for this process.
title: Stellungnahme zum Antrag auf Aufnahme des Infrastruktur- und Forschungszentrums für lebenswissenschaftliche Daten und Informationen (ZB MED/BIBI), Köln/ Bonn/ Bielefeld, in die gemeinsame Förderung durch Bund und Länder nach der Ausführungsvereinbarung WGL
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2022
Subjects: Evaluation
Leibniz-Verfahren
Forschungsinfrastrukturen
Big Data
Bioinformatik
Datenanalyse
datenintensive Wissenschaft

description: Im Zuge der digitalen Transformation des Wissenschaftssystems hin zu Open Science besteht großer Bedarf an Akteuren, die Infrastruktur- und Forschungsdaten verbinden und zielgruppenspezifische Services für deren Analyse anbieten. ZB MED/BIBI ist eine forschende Infrastruktureinrichtung, die das Ziel hat, in der Funktion eines „Digital Enablers“ Literatur und Forschungsdaten für die Lebenswissenschaften zur Verfügung zu stellen („Service for Science“) sowie passgenaue IT-Lösungen für die Handhabung großer Datenmengen in den Lebenswissenschaften zu entwickeln („Science for Services“). Den Antrag der Einrichtung auf Aufnahme in die Leibniz-Gemeinschaft bewertet der Wissenschaftsrat als gut. Er empfiehlt der Einrichtung eine stärkere Profilierung des Forschungsprogramms sowie eine engere Rückkopplung der angebotenen Services an die Nutzungscommunities.
title: MRI findings of cortical malformations in infants presenting with intractable epilepsy- The subtle and the obvious.
Creators: name: Bahri, Nandini
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Congenital
subject: Diagnostic procedure
subject: MR
subject: Paediatric
subject: Neuroradiology brain
subject: CNS

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To provide a brief overview of the MR imaging approach in infants presenting with intractable epilepsy. To present a simplified and clinically relevant classification of congenital cortical malformations. To emphasisethe points thatshould be kept in...
SaxFDM-Fokusprojekt: Publikationsdienst für wissenschaftliche Datenmodelle und Vokabulare (Pudel)
Creators: name: Goldhahn, Dirk
name: Kretschmer, Uwe
name: Mühleder, Peter
name: Naether, Franziska
name: Becker, Anja
name: Graiff, Cecilia
Publisher: name: Zenodo
Year: 2022
Subjects: SaxFDM-Tagung
Fokusprojekt

description: Die Arbeit mit digitalen Daten in den Geisteswissenschaften kann auf vielfältige Weise stattfinden. Allen gemein ist jedoch, dass eine Form der Datenmodellierung vorangeht. Die Frage, wie diese Datenmodelle dokumentiert, veröffentlicht und nachnutzbar ge­macht werden, spielt dabei oft keine zentrale Rolle, wodurch vie­les der konzeptionellen Arbeit, die hinter den Modellen steckt, oft nur schwer auffindbar und nachvollziehbar bleibt. An der Sächsischen Akademie der Wissenschaften zu Leipzig (SAW) ist im Januar dieses Jahres daher das zunächst einjährige Vorhaben „Publikationsdienst für wissenschaftliche Datenmodelle und Vokabu­lare“ (Pudel) gestartet. Dabei handelt es sich um ein Fokusprojekt von SaxFDM, der sächsischen Landesinitiative für Forschungsdatenma­nagement. Es wird vom KompetenzwerkD der SAW koordiniert. Ziel dieses Projektes ist es, einen Publikations- und Dokumen­tationsdienst zu schaffen, der es erlaubt, unterschiedliche Da­tenmodelle (RDF-basierte Vokabulare, Ontologien, XML-Schemas, etc.) auf standardisierte Weise zu dokumentieren und zu veröf­fentlichen. Dieser Ansatz stellt ein Novum gegenüber bereits vor­handenen Diensten dar. Durch den dynamischeren Ansatz dieses Projektes wird es möglich sein, die unterschiedlichen Datenmodel­le, die in diversen Forschungsprojekten entstehen, übersichtlich darstellbar und einsehbar zu machen. Hierbei soll eine Nutzung der Datenmodelle im Sinne der FAIR-Prinzipien für Forschungsda­ten erfolgen: Findable (auffindbar), Accessible (zugänglich), Inter­operable (kompatibel), Reusable (wiederverwendbar). Um einen standardisierten Weg der Bereitstellung, Präsenta­tion und Dokumentation von Datenmodellen zu definieren, strebt das Projekt einen Austausch sowohl mit Partnern aus SaxFDM, als auch auf nationaler Ebene mit den Konsortien für die Nationale Forschungsdateninfrastruktur (NFDI) an, um eine längerfristige Anbindung an nationale Infrastrukturbestrebungen zu erreichen.
Endowing the Standard Model with new r-symmetry
Creators: name: Chang, Ngee-Pong
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the Standard Model, there is the single Higgs field, $ϕ$, which gives rise to constituent quark and lepton masses. The Yukawa coupling is a highly complex set of $3 \times 3$ matrices, resulting in many textures of quark and lepton masses. In this talk, we propose to transfer the complexity of the Yukawa coupling matrices to a family of Higgs fields, so that the Yukawa coupling itself becomes a simple interaction. In the context of an Enriched Standard Model, we introduce a new $r$-symmetry in the extended $SU(2)_L \times U(1)_Y \times U(1)_R$ model and show how a particularly simple scenario results in a near degeneracy of masses in the $126-GeV$ region, with a hierarchy of heavier masses suggested by the quark and lepton texture mass matrices.
description: Talk presented at International Conference on Flavor Physics and Mass Generation, Feb 10-14, 2014 at Institute of Advanced Studies, NTU, Singapore
Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis
Creators: name: Wang, Zhongjing
name: Willis, Monte S.
name: Xie, Liang
name: Pi, Xinchun
name: He, Jun
name: Patterson, Cam
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: PHD3, a member of a family of Prolyl-4 Hydroxylase Domain (PHD) proteins, has long been considered a pro-apoptotic protein. Although the pro-apoptotic effect of PHD3 requires its prolyl hydroxylase activity, it may be independent of HIF-1α, the common substrate of PHDs. PHD3 is highly expressed in the heart, however, its role in cardiomyocyte apoptosis remains unclear. This study was undertaken to determine whether inhibition or depletion of PHD3 inhibits cardiomyocyte apoptosis and attenuates myocardial injury induced by ischemia-reperfusion (I/R). PHD3 knockout mice and littermate controls were subjected to left anterior descending (LAD) coronary artery ligation for 40 minutes followed by reperfusion. Histochemical analysis using Evan’s Blue, triphenyl-tetrazolium chloride and TUNEL staining, demonstrated that myocardial injury and cardiomyocyte apoptosis induced I/R injury were significantly attenuated in PHD3 knockout mice. PHD3 knockout mice exhibited no changes in HIF-1α protein level, the expression of some HIF target genes or the myocardium capillary density at physiological condition. However, depletion of PHD3 further enhanced the induction of HIF-1α protein at hypoxic condition and increased expression of HIF-1α inhibited cardiomyocyte apoptosis induced by hypoxia. In addition, it has been demonstrated that PHD3 plays an important role in ATR/Chk1/p53 pathway. Consistently, a prolyl hydroxylase inhibitor or depletion of PHD3 significantly inhibits the activation of Chk1 and p53 in cardiomyocytes and the subsequent apoptosis induced by doxorubicin, hydrogen peroxide or hypoxia/re-oxygenation. Taken together, these data suggest that depletion of PHD3 leads to increased stabilization of HIF-1α and inhibition of DNA damage response, both of which may contribute to the cardioprotective effect seen with depletion of PHD3.
Um indicador de aprendizagem não-linear para EaD online fundamentado no modelo de avaliação Learning Vectors (LV)
Creators: name: Sales, Gilvandenys Leite
name: Cordeiro Barroso, Giovanni
name: Marques Soares, José
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 390402
subject: Education assessment and evaluation

description: Embora os AVA apresentem indicadores de desempenho automatizados, em geral, privilegiam-se os aspectos quantitativos, limitando-se a contabilização do número de acessos, registro de interações entre participantes, além de dados e gráficos estatísticos. Neste trabalho, propõe-se uma contribuição ao processo avaliativo nos ambientes virtuais. Para tanto, foi desenvolvido um instrumento semi-automatizado de avaliação de caráter quali-quantitativo, voltado para uma prática avaliativa contínua, formativa e mediadora do processo ensino-aprendizagem, capaz de auxiliar os aprendizes no gerenciamento de seu desempenho e contribuir para a redução da sobrecarga de trabalho dos Professores/Tutores gerada a partir da análise offline dos muitos arquivos enviados.
Digitaliserede folkeregisterfilm
Creators: Høje Taastrup Kommune
Høje-Taastrup Kommune Kommune
Publisher: name: Rigsarkivet
Year: 2025

description: Afgangsregistret indeholder et folkeregisterkort for hver af de indbyggere, der er fraflyttet kommunen, eller som boede i kommunen i 1970. Kvinder og børn er anført på ægtemandens kort.
Catalysis of Strand Exchange by the HSV-1 UL12 and ICP8 Proteins: Potent ICP8 Recombinase Activity is Revealed upon Resection of dsDNA Substrate by Nuclease
Creators: name: Reuven, Nina B.
name: Griffith, Jack D.
name: Weller, Sandra K.
name: Willcox, Smaranda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: The replication of herpes simplex virus type 1 (HSV-1) is associated with a high degree of homologous recombination, which is likely to be mediated, in part, by HSV-1-encoded proteins. We have previously shown that the HSV-1 encoded ICP8 protein and alkaline nuclease UL12 are capable of catalyzing an in vitro strand-exchange reaction. Here, we show, by electron microscopy, that the products of the strand exchange reaction between linear double-stranded DNA and circular single-stranded DNA consist of the expected joint molecule forms: sigma, alpha, and gapped circles. Other exonucleases, such as lambda Red α, which, like UL12, digests 5′-3′, as well as Escherichia coli exonuclease III (ExoIII), which digests 3′-5′, could substitute for UL12 in the strand exchange reaction by providing a resected DNA end. ICP8 generated the same intermediates and strand exchange products when the double-stranded DNA substrate was preresected by any of the nucleases. Using substrates with large regions of non-homology we found that pairing by ICP8 could be initiated from the middle of a DNA molecule and did not require a homologous end. In this reaction, the resection of a DNA end by the nuclease is required to reveal homologous sequences capable of being paired by ICP8. This study further illustrates the complexity of the multi-functional ICP8 protein.
Turbulence-Induced Relative Velocity of Dust Particles III: The Probability Distribution
Creators: name: Pan, Liubin
name: Padoan, Paolo
name: Scalo, John
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Motivated by its important role in the collisional growth of dust particles in protoplanetary disks, we investigate the probability distribution function (PDF) of the relative velocity of inertial particles suspended in turbulent flows. Using the simulation from our previous work, we compute the relative velocity PDF as a function of the friction timescales, tau_p1 and tau_p2, of two particles of arbitrary sizes. The friction time of particles included in the simulation ranges from 0.1 tau_eta to 54T_L, with tau_eta and T_L the Kolmogorov time and the Lagrangian correlation time of the flow, respectively. The relative velocity PDF is generically non-Gaussian, exhibiting fat tails. For a fixed value of tau_p1, the PDF is the fattest for equal-size particles (tau_p2~tau_p1), and becomes thinner at both tau_p2tau_p1. Defining f as the friction time ratio of the smaller particle to the larger one, we find that, at a given f in 1/2>T_L). These features are successfully explained by the Pan & Padoan model. Using our simulation data and some simplifying assumptions, we estimated the fractions of collisions resulting in sticking, bouncing, and fragmentation as a function of the dust size in protoplanerary disks, and argued that accounting for non-Gaussianity of the collision velocity may help further alleviate the bouncing barrier problem.
description: 25 pages, 19 figures, accepted by ApJ
Multisite Promiscuity in the Processing of Endogenous Substrates by Human Carboxylesterase 1
Creators: name: Edwards, Carol C.
name: Kuhn, Peter
name: Redinbo, Matthew R.
name: Bencharit, Sompop
name: Morton, Christopher L.
name: Howard-Williams, Escher L.
name: Potter, Philip M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Human carboxylesterase 1 (hCE1) is a drug- and endobiotic-processing serine hydrolase that exhibits relatively broad substrate specificity. It has been implicated in a variety of endogenous cholesterol metabolism pathways including the following apparently disparate reactions: cholesterol ester hydrolysis (CEH), fatty acyl Coenzyme A hydrolysis (FACoAH), acyl-CoenzymeA:cholesterol acyltransfer (ACAT), and fatty acyl ethyl ester synthesis (FAEES). The structural basis for the ability of hCE1 to perform these catalytic actions involving large substrates and products has remained unclear. Here we present four crystal structures of the hCE1 glycoprotein in various complexes with endogenous substrates or substrate analogues: Coenzyme A, the fatty acid palmitate, and the bile acids cholate and taurocholate. While the active site of hCE1 was known to be promiscuous and capable of interacting with a variety of chemically-distinct ligands, these structures reveal that the enzyme contains two additional ligand binding sites and that each site also exhibits relatively non-specific ligand binding properties. Using this multisite promiscuity, hCE1 appears structurally capable of assembling several catalytic events depending, apparently, on the physiological state of the cellular environment. These results expand our understanding of enzyme promiscuity and indicate that, in the case of hCE1, multiple non-specific sites are employed to perform distinct catalytic actions.
Good Design Award 2021 Disaster recovery through Design Science [Reconstruction of Shinchi Town after the 2011 Great East Japan Earthquake]
Creators: name: Uehara, Misato
name: Inoue, Tadayoshi
name: Tokita, Yoshifumi
name: Eda, Ryuzo
Publisher: name: Zenodo
Year: 2021

description: https://www.g-mark.org/award/describe/52729?token=JglCZ9imKq The Great East Japan Earthquake caused enormous damage in many cities, towns and villages. Although nearly 10 years was spent for reconstruction of high seawalls and leveling, the population never recovered. In contrast, utilization of National Land Agency's data reflecting Ian McHarg's design science theory resulted in a smooth housing reconstruction and population recovery in the affected areas.
Clinical characterization, genetic screening and genotype-phenotype associations in cerebellar and brainstem congenital defects
Creators: name: Nuovo, Sara
Publisher: name: Universita degli studi di Salerno
Year: 2020
Subjects: subject: MED/38 PEDIATRIA GENERALE E SPECIALISTICA
subject: Genetics
subject: FOS: Biological sciences
subject: Cerebellum
subject: Brainstem

description: 2018 - 2019
description: Cerebellar and brainstem congenital defects (CBCDs) represent a wide spectrum of malformative disorders resulting from abnormal development of midbrain-hindbrain and characterised by high clinical and genetic heterogeneity. Due to the uncommonness of these conditions and the substantial under-recognition on brain imaging studies, limited information is available on their prevalence, genetic causes, natural history, and genotype-phenotype associations. Such a contingency of factors leads to uncertain prognosis and wrong counselling. .. [edited by the Author]
title: Pre-liver transplantation workup; what should the radiologist look for.
Creators: name: Tawk, Sammy
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Abdomen
subject: Liver
subject: Anatomy
subject: CT
subject: MR
subject: Ultrasound
subject: Diagnostic procedure
subject: Complications
subject: Normal variants
subject: Transplantation
subject: Cirrhosis

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Enumerate the critical radiological findings that should be mentioned in pre-liver transplantation workup in the living donor and the recipient. Discuss the importance of these findings in the surgical outcome. Review the different related imaging...
C'è in gioco la libertà! Fare public history sulla Repubblica di Montefiorino con un board game collaborativo
Creators: name: Asti, Chiara
Publisher: name: C. Asti, C'è in gioco la libertà! Fare public history sulla Repubblica di Montefiorino con un board game collaborativo, Università degli Studi di Modena e Reggio Emilia, 201
Year: 2016

description: La public history in Italia è una disciplina non ancora formalizzata, praticamente ignorata a livello accademico, anche se negli ultimi anni alcuni storici hanno iniziato a ragionare su questa materia. Sul mercato, invece, esistono varie esperienze di quella che oltreoceano è definita come public history: i vari musei d'impresa che vogliono valorizzare il proprio marchio; le iniziative degli Istituti storici con le Pubbliche amministrazioni, le associazioni e le scuole del territorio, come ad esempio i viaggi della memoria; le raccolte di fonti con la partecipazione attiva dei privati. In Italia ci sono anche esempi di aziende che lavorano dichiaratamente nel campo della public history, come “Cliomedia Officina”. La mancanza di un ragionamento teorico e di una formalizzazione accademica non hanno quindi impedito lo sviluppo e la diffusione di pratiche attive di public history. Uno dei settori di sua pertinenza è rappresentato indubbiamente dai musei. Molti musei infatti si preoccupano di coinvolgere il pubblico, modulando l'offerta a seconda dei possibili destinatari. Inoltre escono sul territorio e fanno la storia delle comunità coinvolgendole. I programmi e i siti dei musei, anche in Italia, mostrano ormai la chiara intenzione di superare un ruolo esclusivamente conservativo per concentrarsi sulle pratiche di valorizzazione e promozione culturale. Nell'attività didattica e divulgativa i musei ricorrono sempre più spesso a pratiche ludiche. Il gioco è una modalità di apprendimento attiva e partecipata, che quindi risponde perfettamente ai canoni della public history. Non solo i giocatori rappresentano un audience preferenziale per la storia, ma il gioco stesso è uno strumento ideale per fare storia “in” e “con” il pubblico.
title: Stellungnahme zum Friedrich-Loeffler-Institut - Bundesforschungsinstitut für Tiergesundheit, Insel Riems
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2022
Subjects: Tiergesundheit
Forschungseinrichtungen
Ressortforschung
Tierseuchen
Tierschutz
Landwirtschaftsministerium
Klimawandel

description: Das Friedrich-Loeffler-Institut forscht zur Vermeidung und Bekämpfung von Tierseuchen und zum Schutz des Menschen vor Zoonosen sowie zu den Themen Tierschutz und Tierwohl. Auf der Grundlage seiner ausgezeichneten Forschung berät das Institut das Bundesministerium für Ernährung und Landwirtschaft sowie weitere Bundes- und Landesministerien und trägt somit zur Weiterentwicklung der Landwirtschaftspolitik bei. Als besonders zukunftsweisend bewertet der Wissenschaftsrat die Erweiterung des Forschungsspektrums um den Bereich One Health, der die Gesundheit von Mensch, Tier und Umwelt integriert betrachtet.
Paul-Bunnell tested cohort
Creators: Statens Serum Institut
Klaus Rostgaard
Publisher: name: Rigsarkivet
Year: 2025

description: At undersøge risikofaktorer for infektiøs mononukleose (kyssesyge), og følgevirkninger af samme, baseret på en kohorte som er testet for nylig infektion med Epstein-Barr virus. Eksistensen af personer der tester positiv hhv negativ, men med de samme indikationer gør den kausale inferens meget stærkere: at sen eller nylig infektion med Epstein-Barr virus (evt.) påvirker risikoen for det (sygdoms-) udfald man studerer.
Two Distinct Binding Modes of a Protein Cofactor with its Target RNA
Creators: name: Hong, Minh
name: Liu, Shixin
name: Weeks, Kevin M.
name: Zhuang, Xiaowei
name: Nivón, Lucas G.
name: Chai, Geqing
name: Bokinsky, Gregory
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Like most cellular RNA enzymes, the bI5 group I intron requires binding by a protein cofactor to fold correctly. Here, we use single-molecule approaches to monitor the structural dynamics of the bI5 RNA in real time as it assembles with its CBP2 protein cofactor. These experiments show that CBP2 binds to the target RNA in two distinct modes with apparently opposite effects: a “nonspecific” mode that forms rapidly and induces large conformational fluctuations in the RNA, and a “specific” mode that forms slowly and stabilizes the native RNA structure. The bI5 RNA folds though multiple pathways toward the native state, typically traversing dynamic intermediate states induced by nonspecific binding of CBP2. These results suggest that the protein cofactor-assisted RNA folding involves sequential nonspecific and specific protein-RNA interactions. The nonspecific interaction increases the local concentration of CBP2 and the number of conformational states accessible to the RNA, potentially promoting the formation of specific RNA-protein interactions.
title: Stellungnahme zum Institut für Präventivmedizin der Bundeswehr (InstPrävMedBw), Andernach
Creators: name: German Science And Humanities Council
Publisher: name: German Science and Humanities Council
Year: 2022
Subjects: Evaluation
Ressortforschung
Präventivmedizin
Epidemiologie
Arbeitsphysiologie
Sportmedizin
Gesundheitsaktenarchiv

description: Das 2017 gegründete Institut für Präventivmedizin der Bundeswehr trägt mit seiner interdisziplinären Forschung dazu bei, eine effiziente Rekrutenauswahl durchzuführen, die Einsatzfähigkeit der Soldatinnen und Soldaten zu verbessern sowie physischen und psychischen Erkrankungen vorzubeugen. Das Institutsprofil ist unklar und muss geschärft werden. Da die beiden Abteilungen des Instituts kaum miteinander verbunden sind, sollte das Institut eine Integrationsstrategie und ein Forschungsprogramm entwickeln, das beide Institutsteile einbindet. Zur Unterstützung dieses dieses Strategieprozesses sollte das Bundesministerium der Verteidigung ein hochrangig besetztes Gremium einrichten. Zudem sind zusätzliche Stellen für wissenschaftliches Personal erforderlich. Die wertvollen Gesundheitsakten des Institutsarchivs sollten dringend digitalisiert werden.
The 3 $μ$m Spectrum of Jupiter's Irregular Satellite Himalia
Creators: name: Brown, M. E.
name: Rhoden, A. R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present a medium resolution spectrum of Jupiter's irregular satellite Himalia covering the critical 3 $μ$m spectral region. The spectrum shows no evidence for aqueously altered phyllosilicates, as had been suggested from the tentative detection of a 0.7 $μ$m absorption, but instead shows a spectrum strikingly similar to the C/CF type asteroid 52 Europa. 52 Europa is the prototype of a class of asteroids generally situated in the outer asteroid belt between less distant asteroids which show evidence for aqueous alteration and more distant asteroids which show evidence for water ice. The spectral match between Himalia and this group of asteroids is surprising and difficult to reconcile with models of the origin of the irregular satellites.
description: ApJL, in press
title: Imaging Interpretation of Unusual Tumors of the Breast
Creators: name: Gkali, Christina
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Breast
subject: Mammography
subject: Ultrasound
subject: Elastography
subject: Contrast agent-intravenous
subject: Cancer

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1) to present and discuss clinical and imaging features of uncommon tumors, both benign and malignant, of the breast 2)to present the role of pathology in...