cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Three-Dimensional Seepage Simulation of a Tailings Storage Facility : A Case Study
Creators: name: Karimi, Zana
name: Redmond, John
name: Kafash, Masood H.
name: Katapa, Kanyembo
name: Davidson, Richard
name: Tyler, Hadleigh
Publisher: name: The University of British Columbia
Year: 2023

description: Seepage response to tailings deposition and subsequent pore pressure condition characterization within the embankments of tailings dams are important in evaluating their performance under static and dynamic loading conditions. In this study, three-dimensional seepage response in a large tailings storage facility under tailings deposition and embankment raise was evaluated in the FEFLOW numerical platform. The simulation model considers interactions among the reclaim pond, deposited slurry, embankment, perimeter wells, and regional ground water table, analyzing both saturated and unsaturated flow conditions. The numerical model was first calibrated to the past and existing conditions, in which initial material properties were assigned based on field and laboratory testing, and then were adjusted through an iterative process until the pore pressure conditions in the model generally matched measured values. The documented piezometer measurements and pore pressure dissipation test results were used as calibration targets. The calibrated model was then used to project responses into the future for varied tailings deposition rates. The embankment crest and reclaim pond were evaluated in a series of raise steps over the time in a transient seepage analysis that accounted for consolidation-induced excess pore pressures under the increased overburden stresses. The effects of the raise rate, depositional scheme, and material water storage capacity on the projected pore pressure conditions were also evaluated. The results indicate that the numerical model can predict seepage response and pore pressure conditions reasonably well. The outcomes of such models provide more insights into the seepage performance of the tailings storage facilities. Additionally, pore pressure responses can be used in the framework of performance-based design to assist geotechnical engineers in evaluating embankment stability and to better inform decision-makers by reducing uncertainties. Such studies highlight the importance of using numerical models to evaluate the seepage response in tailings storage facilities. By providing a better understanding of the seepage performance, these models can help mining companies to identify potential risks and improve their management practices, ultimately leading to safer and more sustainable mining operations.
TRATAMENTO DE LESÃO POR PRESSÃO DECORRENTE DO USO DE ÓRTESE: RELATO DE CASO
Creators: name: Castilho, João Cezar
name: Bento, Maria Madalena Souza
name: Oliveira, Pedro Gonçalves De
Publisher: name: figshare
Year: 2019
Subjects: subject: 111004 Clinical Nursing: Tertiary (Rehabilitative)
subject: FOS: Health sciences
subject: 111502 Clinical Pharmacology and Therapeutics
subject: FOS: Clinical medicine
subject: 110304 Dermatology

description: Lesões por pressão (LP) decorrem da pressão intensa e/ou prolongada em combinação com o cisalhamento local. Apesar da ocorrência de LP ser considerada um evento adverso que pode, na maioria das vezes, ser passível de prevenção, existem ocasiões em as condições do paciente as tornam inevitáveis. Este estudo relata experiência no tratamento de paciente portador de LP no maléolo direito com o uso de creme de AH 0,2%. O paciente foi atendido pela equipe multidisciplinar do Programa Melhor em Casa de Jaguariúna-SP. Jovem, masculino, 19 anos, vítima de espancamento, resultando em traumatismo cranioencefálico grave, permanecendo em coma por alguns dias. Estava tetraplégico, em reabilitação e fazia uso de órteses nos membros inferiores (MIs), que causou compressão no maléolo direito, culminando em LP. Tecido necrótico foi removido por meio de desbridamento instrumental e iniciada limpeza diária com soro fisiológico (SF) 0,9% e aplicação diária de fina camada de creme à base de AH 0,2%. Após 34 dias de tratamento com AH tópico, foi verificada a completa reparação cutânea da LP, revelando efetividade do protocolo empregado.
Supplemental Material for Devkota et al., 2021
Creators: name: Devkota, Ranjan
name: Kaper, Delaney
name: Bodhicharla, Rakesh
name: Henricsson, Marcus
name: Borén, Jan
name: Pilon, Marc
Publisher: name: GSA Journals
Year: 2021
Subjects: subject: Cell Biology
subject: 60104 Cell Metabolism
subject: FOS: Biological sciences
subject: 60103 Cell Development, Proliferation and Death
subject: Genetics
subject: Molecular Biology
subject: Physiology

description: This file contains supplemental figures to the article entitled "A Genetic Titration of Membrane Composition in C. elegans Reveals its Importance for Multiple Cellular and Physiological Traits".
Angeliticin B, a new chromone isolated from Angelica polymorpha Maxim
Creators: name: Yang, Li
name: Dai, Yanlin
name: Wang, Jianzhong
name: Chen, Donglin
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Cell Biology
Pharmacology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: A new chromone, angeliticin B (1) together with nine known compounds, psoralene (2), isoimperatorin (3), (S)-(-)-2′-methoxypeucedanin hydrate (4), (S)-(-)-oxypeucedanin (5), xanthotoxin (6), isopimpinellin (7), 1′-O-β-D-glucopyranosyl-(2′S, 3′R)-3′-hydroxymarmesin (8), sec-O-glucosylhamaudol (9) and vanillin (10) were isolated from the methanol extract of Angelica polymorpha Maxim. The structures of these compounds were elucidated through a comprehensive analysis of standard spectral data (MS, IR, and NMR). Compound 1 exhibited antioxidant activity with IC50 = 198.57 μM in DPPH experiment and 31.71 μM in ABTS experiment. Compound 2, 6, 7 exhibited ABTS radical scavenging activity with IC50 ranging from 105.96 μM to 167.67 μM. Compound 3 demonstrated a synergistic induction effect on nigericin-activated NLRP3 inflammasome in THP-1 cell by LDH release method.
The Inert Doublet Model at current and future colliders
Creators: name: Kalinowski, Jan
name: Kotlarski, Wojciech
name: Robens, Tania
name: Sokolowska, Dorota
name: Zarnecki, Alexander Filip
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We discuss the status of the Inert Doublet Model, a two-Higgs doublet model that obeys a discrete Z2 symmetry and provides a dark matter candidate. We discuss all current theoretical and experimental constraints on the model as well as discovery prospects at current and future colliders.
description: 6 pages, 3 figures; to be published in the proceedings of DISCRETE2018: 6th Symposium on Prospects in the Physics of Discrete Symmetries, Vienna, 26.-30.11.18; v2: minor changes; corresponds to accepted proceedings version
Instantons on Noncommutative R^4 and Projection Operators
Creators: name: Furuuchi, Kazuyuki
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Quantum Algebra (math.QA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: I carefully study noncommutative version of ADHM construction of instantons, which was proposed by Nekrasov and Schwarz. Noncommutative ${\bf R}^4$ is described as algebra of operators acting in Fock space. In ADHM construction of instantons, one looks for zero-modes of Dirac-like operator. The feature peculiar to noncommutative case is that these zero-modes project out some states in Fock space. The mechanism of these projections is clarified when the gauge group is U(1). I also construct some zero-modes when the gauge group is U(N) and demonstrate that the projections also occur, and the mechanism is similar to the U(1) case. A physical interpretation of the projections in IIB matrix model is briefly discussed.
description: 29 pages, LaTeX, no figures, further explanations on holes on branes added, minor mistakes corrected
USE OF HYALURONIC ACID IN THE TREATMENT OF PRESSURE INJURY: CASE REPORT
Creators: name: Castilho, João Cezar
name: Bento, Maria Madalena Souza
name: Oliveira, Pedro Gonçalves De
Publisher: name: figshare
Year: 2019
Subjects: subject: 111004 Clinical Nursing: Tertiary (Rehabilitative)
subject: FOS: Health sciences
subject: 111502 Clinical Pharmacology and Therapeutics
subject: FOS: Clinical medicine
subject: 110304 Dermatology

description: Pressure injuries (PIs) arise from the intense and/or prolonged pressure associated with local shear. Although the occurrence of PIs is considered an adverse event that can generally be preventable, there are occasions when the conditions of the patient make them unavoidable. This study reports experiences connected with the treatment of PIs from different etiologies. The patients were attended by the multidisciplinary team of the Programa Melhor em Casa de Jaguariúna-SP. Case 1 - male, 19 years old, beating victim, resulting in severe cranioencephalic trauma, remaining in coma for a few days. He was quadriplegic, under rehabilitation and used orthesis in the lower limbs (LLs), which compressed the right malleolus, resulting in PI. Necrotic tissue was removed by means of instrumental debridement and daily cleansing with 0.9% saline solution (SS) and daily application of a thin layer of 0.2% HA cream. Case 2 - woman, 79 years old, smoker, obese, with systemic arterial hypertension, type 2 diabetes, COPD, osteoporosis, anemia, femoral fracture and PI in the sacral region of stage 2 and in the right ischium. It was used, without success, dressings involving daily cleaning with 0.9% SS and application of essential fatty acids (EFA) in the treatment of PI. A protocol was started with daily cleaning with 0.9% SS and daily application of a thin layer of cream based on 0.2% HA. After 15 to 34 days of treatment with topical HA, the complete cutaneous repair of the PIs was verified, revealing the effectiveness of the protocol used.
Seismic Liquefaction Potential Assessment by Artificial Neural Networks
Creators: name: Oboudi, Marjan
name: Dávila, Rafael
Publisher: name: The University of British Columbia
Year: 2023

description: Soil liquefaction occurs in loose, cohesionless soils (i.e., sands and silts) and in sensitive clays when a sudden loss of strength and stiffness is experienced, sometimes resulting in large, permanent displacements of the ground and/or geo-structures. The most common procedures used in practice for the evaluation of liquefaction potential in soils and tailings materials are based on identification of the occurrence or nonoccurrence of liquefaction through the analysis of liquefaction case histories using empirical, simple regression, or statistical methods. In this study, a variety of machine learning (ML) and empirical methods were applied to evaluate seismic liquefaction potential based on actual field records. The performance of each method was evaluated, and the results were compared to demonstrate the efficacy of each method.
On the integrability of nonlinear partial differential equations
Creators: name: Dorren, H. J. S.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: We investigate the integrability of Nonlinear Partial Differential Equations (NPDEs). The concepts are developed by firstly discussing the integrability of the KdV equation. We proceed by generalizing the ideas introduced for the KdV equation to other NPDEs. The method is based upon a linearization principle which can be applied on nonlinearities which have a polynomial form. We illustrate the potential of the method by finding solutions of the (coupled) nonlinear Schrödinger equation and the Manakov equation which play an important role in optical fiber communication. Finally, it is shown that the method can also be generalized to higher-dimensions.
description: 12 pages Latex
Pollicott-Ruelle resonant states and Betti numbers
Creators: name: Küster, Benjamin
name: Weich, Tobias
Publisher: name: arXiv
Year: 2019
Subjects: subject: Spectral Theory (math.SP)
subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 58J50, 58C40, 11M36

description: Given a closed orientable hyperbolic manifold of dimension $\neq 3$ we prove that the multiplicity of the Pollicott-Ruelle resonance of the geodesic flow on perpendicular one-forms at zero agrees with the first Betti number of the manifold. Additionally, we prove that this equality is stable under small perturbations of the Riemannian metric and simultaneous small perturbations of the geodesic vector field within the class of contact vector fields. For more general perturbations we get bounds on the multiplicity of the resonance zero on all one-forms in terms of the first and zeroth Betti numbers. Furthermore, we identify for hyperbolic manifolds further resonance spaces whose multiplicities are given by higher Betti numbers.
description: 18 pages. To appear in Communications in Mathematical Physics
Targeting neurons with small molecule probes: from imaging to modulation
Creators: Boltaev, Umed Tolibovich
Publisher: name: Columbia University
Year: 2018
Subjects: subject: Chemistry
subject: Biochemistry
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Neurons
subject: Molecular probes

description: Our body is governed through a complex network of diverse set of synapses created by many different neurons, which extend throughout the body. A great progress has been made to monitor and modulate these cells using genetic methods in limited settings, while chemical approaches have not achieved comparable successful results. Yet given the versatility of chemical probes, it has been important to create platforms which would allow us to generate compounds with characteristics of neuronal targeting and modulation.
      In our effort to modulate neurons and their synapses, a platform of assays was developed to find agonists and modulators of the brain derived neurotrophic factor, BDNF, and its receptor, TrkB, which is a central signaling system for neurogenesis and synaptic plasticity. These assays were used to evaluate reported TrkB agonists and perform a high throughput screen. In addition, an alternative approach in the form of phage display targeting TrkB was employed, since TrkB proved to be a challenging target for identification of small molecule agonist or modulator.
      To visualize different parts as well as various types of neurons, two different platforms were developed. A diversity oriented fluorescent library coupled with high content screening provided an opportunity to identify probes that could specifically stain neurons and synapses. In the second approach a new phage display method was developed that could identify probes with the ability to bind to neuronal cell surface markers. The developed platforms that we developed have a great potential to generate promising probes for vast array of applications.
title: Forschungsarbeiten des Instituts für Werkstoffe der Technischen Universität Braunschweig
Creators: name: Haessner, Frank
Publisher: name: Goltze
Year: 1993
Subjects: subject: Brunsvicensien der Universitätsbibliothek Braunschweig
subject: Jahrbuch der BWG
subject: 62

description: Das Institut für Werkstoffe ist aus einer Reihe von Zusammenlegungen und Aufteilungen innerhalb der letzten 50 Jahre hervorgegangen. Aus dem um 1930 bestehenden Laboratorium für Festigkeitsuntersuchungen mit Wöhler-Institut und dem Technologischen Institut für Schweißtechnik ist es schließlich durch Ausgliederung der Schweißtechnik entstanden. Es wird von einem Vorstand, bestehend aus Herrn Prof. Günter Lange und dem Verfasser, geleitet.
Das Institut für Werkstoffe ist eine vorwiegend experimentell arbeitende wissenschaftliche Einrichtung mit einem großen Gerätepark. Es ist zuständig für die Grundausbildung aller Studenten in Werkstoffkunde für die Fachbereiche "Maschinenbau" und "Elektrotechnik". Dem Institut ist eine amtlich anerkannte Materialprüfstelle für Werkstoffe des Maschinenbaus angegliedert. Die Schwerpunkte der gegenwärtigen Forschungsaktivitäten liegen auf den Gebieten des mechanischen und des thermischen Verhaltens von metallischen Werkstoffen. Das Interesse erstreckt sich dabei sowohl auf "klassische" Werkstoffe, wie beispielsweise Aluminium- oder Kupferlegierungen oder Stähle, als auch auf "moderne" Werkstoffe, von denen amorphe Legierungen, sogenannte metallische Gläser, oder nanokristalline Materialien beispielhaft genannt seien. Im einzelnen lassen sich die Aktivitäten fünf Arbeitsgebieten zuordnen.
Lobelia duriprati T. C. E. Fr.
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Lobelia
Lobelia duriprati

description: Lobelia duriprati T.C.E.Fr.  —
Habit: Herb.
Habitat: LMWF, LMDF, BZ; 1 600–3 600 m. Distribution: IIIa.
 Voucher: Near Mount Kenya Lodge, Alt. 2 972 m, 21 Jul. 2014, CPG 28528 (HIB, PE).
References: Fries (1923a), Blundell (1987), Bussmann (1993, 1994), Bussmann & Beck (1995b), Agnew (2013).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 89, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
Twist cut-off for scalar off-cone operators in q-space
Creators: name: Geyer, Joerg Eilers Bodo
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We show that the twist decomposition of non-local scalar off-cone QCD-operators, which in $x-$space is infinite, after Fourier transformation with the singular functions $1/(x^2 - {\text{i}} ε)^λ$ for $λ= 1$ and 2 terminates at leading and sub-leading twist, respectively. Therefore, only a finite number of twists contribute to the target mass corrections of light-cone dominated scattering processes. Their explicit expressions may be read off directly from the twist decomposition in $x-$space.
description: 7 pages
Lobelia giberroa Hemsl.
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Lobelia
Lobelia giberroa

description: Lobelia giberroa Hemsl.  —
Habit: Herb.
Habitat: LMWF, LMDF, BZ; up to 3 000 m. Distribution: II.
 Voucher: Naro Moru Track, Alt. 2 546 m, 23 Jul. 2014, SAJIT 002088 (HIB).
References: Moreau (1944), Thulin (1984), Bussmann (1993, 1994), Bussmann & Beck (1995b), Agnew (2013).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 89, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
Cytotoxicity and Preliminary Analysis of the Pro-apoptotic and Cell Cycle Arrest Effects of Lantana ukambensis Against Colorectal Cancer Cells.
Creators: name: Sawadogo, Wamtinga Richard
name: Luo, Yun
name: Elkington, Bethany
name: He, Tong-Chuan
name: Wang, Chong-Zhi
name: Yuan, Chun-Su
Publisher: name: University of Illinois at Chicago
Year: 2021
Subjects: Uncategorized

description: Lantana ukambensis (Vatke) Verdc. (Verbenaceae) is a seasonal herb widely spread in the West African region. The whole plant is used for the treatment of wounds, infections, and inflammatory pathologies. The purpose of this research is to evaluate the cytotoxicity and to analyze the probable pro-apototic, and cell cycle arrest effects of L. ukambensis methylene chloride extract and its fractions against HCT-116 and HT-29 colorectal cancer cells using preliminary tests in order to highlight the interest of this plant in the search of new anticancer molecules. The dried powder of the whole plant was extracted by methylene chloride maceration for 24 hours and the extract was divided into five fractions. The cytotoxicity of the crude extract and fractions were evaluated by the MTS assay. The most active fractions were subjected to some preliminary assays including crystal violet, Hoechst staining, cell cycle arrest, and annexin V/PI assays on the cancer cells to highlight the probable mechanism of action of these fractions. The methylene chloride, ethyl acetate, and 1-butanol fractions of L. ukambensis crude extract demonstrated significant antiproliferative effects on HCT-116 and HT-29 cell growth with IC50 values ranging between 2 to 15 μg/mL. 1-butanol and ethyl acetate fractions decreased the G1 phase by 20.53% and 28.47% and increased the G2/M by 23.47% and 25.90% respectively on HCT-116. Moreover, 1-butanol fraction increased the cumulative value of apoptotic cells by 49.77% on HCT-116 and ethyl acetate fraction increased this value by 53.37% at 15 μg/mL after 48 hours of exposure. The outcome of this study suggests the potential of 1-butanol and ethyl acetate fractions for the isolation of anticancer molecules against colorectal cancer.
Markov partitions for toral $\mathbb{Z}^2$-rotations featuring Jeandel-Rao Wang shift and model sets
Creators: name: Labbé, Sébastien
Publisher: name: arXiv
Year: 2019
Subjects: subject: Dynamical Systems (math.DS)
subject: Metric Geometry (math.MG)
subject: FOS: Mathematics

description: We define a partition $\mathcal{P}_0$ and a $\mathbb{Z}^2$-rotation ($\mathbb{Z}^2$-action defined by rotations) on a 2-dimensional torus whose associated symbolic dynamical system is a minimal proper subshift of the Jeandel-Rao aperiodic Wang shift defined by 11 Wang tiles. We define another partition $\mathcal{P}_\mathcal{U}$ and a $\mathbb{Z}^2$-rotation on $\mathbb{T}^2$ whose associated symbolic dynamical system is equal to a minimal and aperiodic Wang shift defined by 19 Wang tiles. This proves that $\mathcal{P}_\mathcal{U}$ is a Markov partition for the $\mathbb{Z}^2$-rotation on $\mathbb{T}^2$. We prove in both cases that the toral $\mathbb{Z}^2$-rotation is the maximal equicontinuous factor of the minimal subshifts and that the set of fiber cardinalities of the factor map is $\{1,2,8\}$. The two minimal subshifts are uniquely ergodic and are isomorphic as measure-preserving dynamical systems to the toral $\mathbb{Z}^2$-rotations. It provides a construction of these Wang shifts as model sets of 4-to-2 cut and project schemes. A do-it-yourself puzzle is available in the appendix to illustrate the results.
description: v1:26 pages, 10 figures. v2:32 pages, 13 figures. v3: various small fixes
A symmetry-derived mechanism for atomic resolution imaging
Creators: name: Krajnak, Matus
name: Etheridge, Joanne
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We introduce a new image contrast mechanism for scanning transmission electron microscopy (STEM) that derives from the local symmetry within the specimen. For a given position of the electron probe on the specimen, the image intensity is determined by the degree of similarity between the exit electron intensity distribution and a chosen symmetry operation applied to that distribution. The contrast mechanism detects both light and heavy atomic columns and is robust with respect to specimen thickness, electron probe energy and defocus. Atomic columns appear as sharp peaks that can be significantly narrower than for STEM images using conventional disc and annular detectors. This fundamentally different contrast mechanism complements conventional imaging modes and can be acquired simultaneously with them, expanding the power of STEM for materials characterisation.
description: 7 pages, 5 figures
On the quantum super Virasoro algebra
Creators: name: Mansour, Mostafa
Publisher: name: arXiv
Year: 2000
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The quantum super-algebra structure on the deformed super Virasoro algebra is investigated. More specifically we established the possibility of defining a non trivial Hopf super-algebra on both one and two-parameters deformed super Virasoro algebras.
description: 10 pages; latex, non figures
title: Modellierung, Simulation und Steuerung flexibler Fertigungssysteme
Creators: name: Krebs, Volker
name: Rehkopf, Andreas
Publisher: name: Goltze
Year: 1993
Subjects: subject: Brunsvicensien der Universitätsbibliothek Braunschweig
subject: Jahrbuch der BWG
subject: 62

description: Die diesem Beitrag zugrundeliegenden Arbeiten haben das Ziel, Methoden zur Beschreibung und Simulation von diskreten ereignisorientierten dynamischen Prozessen (DEDP) am Beispiel Flexibler Fertigungssysteme (FFS) zu entwickeln und zu erproben, sowie eine Optimierung des Fertigungsablaufs im Sinne einer Regelung vorzunehmen. Dazu wird eine hierarchische Systemstruktur aufgebaut, in der die Methode der Petrinetze (PN), ergänzt durch wissensbasierte Komponenten, zu einem effizienten integrierten Gesamtsystem führen.
Konkret wird eine aus einem Verbund von sechs Bearbeitungsmaschinen bestehende Fertigungsanlage betrachtet, die durch zeitbewertete Petrinetze in zwei Abstraktionsebenen modelliert wird. Die einzelnen Bearbeitungsmaschinen der oberen Modellierungsebene liegen als PN-Module vor und werden auf der unteren Ebene jeweils als detailliertes, ebenfalls modulares PN-Maschinenmodell dargestellt, wobei hier als repräsentative technische Grundlage für den PN-Modellentwurf die Fertigungszelle MD 5 der Firma Gildemeister gewählt wurde. Diese beiden Abstraktionen bilden zusammen das dynamische ereignisdiskrete ProzeßmodeIl (DEDP-Modell) "Petrinetz", das in dem klassischen Ebenenmodell der Fertigungssteuerung nach Bild 1 der Maschinenebene entspricht. Die über der Maschinenebene liegende Steuerungsebene, sowie die darüber liegende PPS-Ebene (PPS: Produktionsplanung und -Steuerung) werden in dem äquivalenten Ebenenmodell - wie es hier Gegenstand der Betrachtung ist - zusammen als DEDP-Ebene "Planung und Steuerung" verstanden (Bild 1). Dabei erfolgt die Steuerung des Fertigungsablaufs in der realisierten PN-Modellstruktur des FFS über einen wissensbasierten Ansatz auf Basis der XPS-Entwicklungsumgebung "Goldworks" unter Einbeziehung deterministischer und heuristischer Optimierungsstrategien. Simulationsuntersuchungen des Fertigungsablaufs gestatten vertieften Einblick in das Systemverhalten und ermöglichen einen Vergleich der Leistungsfähigkeit der eingesetzten Strategien zur Fertigungssteuerung.
Lobelia gregoriana Baker f.
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Lobelia
Lobelia gregoriana

description: Lobelia gregoriana Baker f.  —
Habit: Herb.
Habitat: HZ, AZ, NZ; 3 200–4 500 m. Distribution: IIIa.
 Voucher: Sirimon Track, Alt. 3 522 m, 18 Jul. 2014, CPG 28422 (HIB, PE).
 References: Moreau (1994), Rehder et al. (1981), Thulin (1984), Young & Peacock (1985), Blundell (1987), Bussmann (1993, 1994, 2006), Agnew (2013).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 89, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
Targeting of specific developmental pathways to understand dendritic cell heterogeneity and function
Creators: Lewis, Kanako
Publisher: name: Columbia University
Year: 2012
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Dendritic cells (DC) are cells of the immune system that are specialized in sensing and responding to pathogens. They coordinate innate and adaptive immune responses to different types of pathogens through the release of inflammatory cytokines, secretion of interferon, and presentation of antigen to naïve T cells. Several different subsets of dendritic cells have been distinguished in the spleen and intestine based on their ability to perform these different functions. However, the specific signaling pathways and transcription factors involved in DC subset differentiation and the precise functions of these subsets are not well understood. Plasmacytoid dendritic cells (PDCs) are a subset of dendritic cells that are specialized at the secretion of type I interferon. Through conditional targeting of E2-2, a transcription factor essential for the specification of the PDC lineage, we have demonstrated a vital role for PDCs in the control of acute and chronic viral infections. In addition, deletion of E2-2 was employed to characterize novel E2-2-dependent, alternative CD8 DC fates. Furthermore, we have identified a common pathway for the differentiation of the key T cell-priming populations of CD11b DCs in the spleen and intestine. Specific targeting of Notch2 revealed that splenic CD11b DCs are comprised of at least two functionally and developmentally distinct populations that can be distinguished by their expression of the surface molecule Esam. Deletion of Notch2 in dendritic cells also led to the specific loss of CD103CD11b DCs from the lamina propria of the intestine and a corresponding reduction in IL-17-producing T cells. Throughout these studies, the identification of specific developmental pathways of DC subsets has provided key insights into their different functions.
Lobelia holstii Engl.
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Lobelia
Lobelia holstii

description: Lobelia holstii Engl.  —
Habit: Herb.
Habitat: LMWF, LMDF, BZ, UMF, HZ; 1 700–3 600 m. Distribution: II.
 Voucher: Chogoria Route, Alt. 2 572 m, 22 Jul. 2014, SAJIT 002036 (HIB).
References: Fries (1923a), Bussmann (1993, 1994), Agnew (2013).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 89, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
Targeting primary cilia-mediated mechanotransduction to promote whole bone formation
Creators: Spasic, Milos
Publisher: name: Columbia University
Year: 2018
Subjects: Biomedical engineering
Cilia and ciliary motion
Bones--Growth
Osteoarthritis--Treatment
Transduction

description: Osteoporosis is a devastating condition characterized by decreased bone mass, and affects over 50% of the population over 50 years old. Progression of osteoporosis results in significantly heightened risk of fracture leading to loss of mobility, prolonged rehabilitation, and even mortality due to extended hospitalization. Current therapeutic options exist to combat low bone mass, but these treatments are being met with increasing concern as reports emerge of atypical fractures and necrosis. Thus, new therapeutic strategies are required.
      Bone is highly dynamic, and it has long been known that physical load is a potent stimulus of bone formation. Despite this, none of the current treatments for bone disease leverage the inherent mechanosensitivity of bone – the ability of bone cells to sense and respond to mechanical forces such as exercise. One potential therapeutic target is the primary cilium. Primary cilia are solitary antenna-like organelles, and over the last 20 years have been identified as a critical cellular mechanosensor. Primary cilia and cell mechanotransduction are critical to the function of numerous cells and tissues. Thus, understanding primary cilia-mediated mechanotransduction has potential applications in treating kidney and liver disease, atherosclerosis, osteoarthritis, and even certain cancers. Previous work from our group has demonstrated that disruption of the cilium impairs bone cell mechanosensitivity, resulting in abrogated whole bone adaptation in response to physical load.
      In this thesis we examine the potential of targeting the primary cilium to enhance bone cell mechanosensitivity and promote whole bone formation. First, we demonstrate the pharmacologically increasing primary cilia length significantly enhances cell mechanotransduction. Next, we expand our list of candidate compounds to manipulate ciliogenesis through the use of high-throughput drug screening. We developed an automated platform for culturing, staining, imaging, and analyzing nearly 7000 small molecules with known biologic activity, and classify them based on mechanism of action. One of these compounds is then used in a co-culture model to study the effects of manipulating osteocyte primary cilia-mediated mechanosensing on pro-osteogenic paracrine signaling to promote the activity of bone-forming osteoblasts and osteogenic differentiation of mesenchymal stem cells. Finally, we translate our in vitro findings into an in vivo model of load-induced bone formation using the same compound to enhance cell mechanotransduction. We demonstrate that we can sensitize bones to mechanical stimulation to enhance load-induced bone formation in healthy and osteoporotic animals, with minimal adverse effects. Together, this work demonstrates the therapeutic potential and viability of targeting primary cilia-mediated mechanotransduction for treating bone diseases.
Employment in Innovative Companies in Italian Regions
Creators: name: Leogrande, Angelo
Publisher: name: Zenodo
Year: 2024

description: The European Innovation Scoreboard (EIS) calculates the value of employment in innovative companies in Italian regions. This indicator is a ratio between the number of employees in innovative companies and the total employment for companies with 10 or more employees. Innovative companies are defined as those that have introduced an innovation or engage in any type of innovation activity. Innovation in companies has a profound impact on worker employability, but its effect in companies oriented towards product and process innovation varies from region to region. Business innovation is particularly important during a period of economic recession. The data refers to the twenty Italian regions between 2018 and 2023.
Taste Coding in the Brainstem
Creators: Fishman, Zvi Hershel
Publisher: name: Columbia University
Year: 2019
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Taste
subject: Neurobiology
subject: Senses and sensation
subject: Brain stem

description: Signals for each of the five tastes have previously been shown to be processed by distinct labeled lines from taste receptor cells (TRCs) on the tongue to the ganglion neurons that innervate them. Furthermore, different tastes have been shown to be represented by distinct neurons in the taste cortex. We recorded calcium activity using fiber photometry from genetically defined populations in the mouse rostral nucleus of the solitary tract (rNST), the first brain station receiving taste signals from the tongue. We found that Somatostatin- (Sst) expressing cells respond exclusively to bitter chemicals while Calretinin- (Calb2) expressing cells respond exclusively to sweet chemicals. Immunostaining and viral strategies demonstrated that Sst and Calb2 mark distinct neuronal populations in the rNST. We then showed that optogenetic activation of Sst and Calb2 cells elicits prototypical bitter and sweet behaviors, respectively and demonstrate that ablation of these cells strongly impairs aversion to bitter tastants and attraction to sweet tastants, respectively. These findings reveal how taste information is propagated into the brain.
Non-classical symmetries and the singular manifold method: A further two examples
Creators: name: Estevez, Pilar G.
name: Gordoa, Pilar R.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: This paper discusses two equations with the conditional Painleve property. The usefulness of the singular manifold method as a tool for determining the non-classical symmetries that reduce the equations to ordinary differential equations with the Painleve property is confirmed once more
description: 9 pages (latex), to appear in Journal of Physics A
Tmarus byssinus Tang and Li 2009
Creators: name: Tang, Guo
name: Li, Shuqiang
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Thomisidae
Tmarus
Tmarus byssinus

description: Tmarus byssinus Tang and Li, 2009 Tmarus byssinus Tang and Li 2009b: 49, figs 1A–D, 2A–C, 3A–D, ♂. Material examined. CHINA: Yunnan , Xishuangbanna, Mengla County, Menglun Town, Menglun Nature Reserve, leg. G. Tang and Z.Y. Yao: 1 ♀, Secondary tropical seasonal moist forest (N21º54.984', E101º16.982', 656 m), 16–31 July 2007, G. Zheng; 1 ♀, Lvshilin Forest Park, Limestone tropical seasonal rain forest (N21º54.614', E101º16.890', 640 m), 14 November 2009 (Tang-Yao _ No. 7); 1 ♀, Lvshilin Forest Park, Limestone tropical seasonal rain forest (N21º54.710', E101º16.941', 652 m), 15 November 2009 (Tang-Yao _ No. 9). Distribution. China (Yunnan).
description: Published as part of Tang, Guo & Li, Shuqiang, 2010, Crab spiders from Xishuangbanna, Yunnan Province, China (Araneae, Thomisidae) 2703, pp. 1-105 in Zootaxa 2703 on page 98
description: {"references": ["Li, Z. X., Zhou, Y. F. & Yang, Z. Z. (2009) First description of the female of Stiphropus falciformus (Araneae: Thomisidae). Acta Arachnologica, Tokyo, 58, 65 - 66.", "Tang, G. & Li, S. (2009 b) The crab spiders of the genus Tmarus from Xishuangbanna, Yunnan, China (Araneae: Thomisidae). Zootaxa, 2223, 48 - 68."]}
MPEC 2024-U34 : COMET P/2016 A2 = P/2024 RU145 (Christensen)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: COMET P/2016 A2 = P/2024 RU145 (Christensen)

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Sparse graphs are near-bipartite
Creators: name: Cranston, Daniel W.
name: Yancey, Matthew P.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Combinatorics (math.CO)
subject: Discrete Mathematics (cs.DM)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: A multigraph $G$ is near-bipartite if $V(G)$ can be partitioned as $I,F$ such that $I$ is an independent set and $F$ induces a forest. We prove that a multigraph $G$ is near-bipartite when $3|W|-2|E(G[W])|\ge -1$ for every $W\subseteq V(G)$, and $G$ contains no $K_4$ and no Moser spindle. We prove that a simple graph $G$ is near-bipartite when $8|W|-5|E(G[W])|\ge -4$ for every $W\subseteq V(G)$, and $G$ contains no subgraph from some finite family $\mathcal{H}$. We also construct infinite families to show that both results are best possible in a very sharp sense.
description: 37 pages, 21 figures; incorporates reviewer feedback; to appear in SIAM J. Discrete Math
Waste Dump Failure Runout Analyses : Applying Improved Empirical Correlation Methods to Waste Dump Datasets
Creators: name: White, Trevor
name: Mitchell, Andrew
name: Whittall, John
name: McDougall, Scott
Publisher: name: The University of British Columbia
Year: 2023

description: Mine waste dumps are often constructed as loose, end-dumped slopes on steep terrain. Established practice is well suited for characterizing waste materials and their stability; however, available empirical tools to estimate the potential runout of waste dump failures provide very approximate results. A study in the 1990s established a database of coal mine waste dump failures and developed empirical tools to estimate runout distance and inundation area for mobile failures. The study found limited correlations to the source volume and other attributes, unless events are sorted by foundation conditions and the spreading potential in the travel path. This paper describes a re-evaluation of the earlier waste dump failure database to improve relationships between fall height, deposit volume, and runout length by incorporating additional sitespecific parameters to describe the nature of the runout path. Improved statistical techniques that have previously been applied to rock avalanches and open pit slope failures were used. A good correlation is observed between the runout length equation developed in this paper and the observed deposits when lateral confinement is applied as an indicator variable in a multiple linear regression analysis. This paper provides the methodology to apply the equation in practice and a description of the accuracy practitioners can expect from the relationship. The proposed method is demonstrated by analyzing the 1966 Aberfan failure.
ICER 2021 Supplemental Documents
Creators: name: Letaw, Lara
name: Garcia, Rosalinda
name: Garcia, Heather
name: Perdriau, Christopher
name: Burnett, Margaret
Publisher: name: figshare
Year: 2021
Subjects: Education

description: Supplemental documents for ICER 2021 publication: "Changing the Online Climate via the Online Students: Effects of Three Curricular Interventions on Online CS Students’ Inclusivity"
Paper DOI: https://doi.org/10.1145/3446871.3469742
List of Symbols and Abbreviations/Supplementary text from Extensive eccentric contractions in intact cardiac trabeculae: revealing compelling differences in contractile behaviour compared to skeletal muscles
Creators: name: Tomalka, André
name: Röhrle, Oliver
name: June-Chiew Han
name: Pham, Toan
name: Taberner, Andrew J.
name: Siebert, Tobias
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Structural Biology
subject: 110601 Biomechanics
subject: FOS: Health sciences

description: Abbreviations, S1 Muscle Preparation, S2 Experimental Setup, S3 Isometric stress-length relation, S4 Functional relevance of force enhancement, T1 Means + SDs of redeveloped (Pim_red) isometric stress after stretch contraction and stress (Pim_pre) of the isometric reference contraction
Sub-picosecond photo-induced displacive phase transition in two-dimensional MoTe$_2$
Creators: name: Peng, Bo
name: Zhang, Hao
name: Chen, Weiwen
name: Qiu, Zhi-Jun
name: Shao, Hezhu
name: Zhu, Heyuan
name: Monserrat, Bartomeu
name: Fu, Desheng
name: Weng, Hongming
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Photo-induced phase transitions (PIPTs) provide an ultrafast, energy-efficient way for precisely manipulating the topological properties of transition-metal ditellurides, and can be used to stabilize a topological phase in an otherwise semiconducting material. Using first-principles calculations, we demonstrate that the PIPT in monolayer MoTe$_2$ from the semiconducting 2H phase to the topological 1T$'$ phase can be triggered purely by electronic excitations that soften multiple lattice vibrational modes. These softenings, driven by a Peierls-like mechanism within the conduction bands, lead to structural symmetry breaking within sub-picosecond timescales, which is shorter than the timescale of a thermally driven phase transition. The transition is predicted to be triggered by photons with energies over $1.96$\,eV, with an associated excited carrier density of $3.4\times10^{14}$\,cm$^{-2}$, which enables a controllable phase transformation by varying the laser wavelength. Our results provide insight into the underlying physics of the phase transition in 2D transition-metal ditellurides, and show an ultrafast phase transition mechanism for manipulation of the topological properties of 2D systems.
description: 3
CW simplicial resolutions of spaces, with an application to loop spaces
Creators: name: Blanc, David
Publisher: name: arXiv
Year: 1999
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 55Q05 (Primary) 55P35, 18G55, 55Q35 (Secondary)

description: We show how a certain type of CW simplicial resolutions of space by wedges of spheres may be constructed for any topological space, and how such resolutions yield an obstruction theory for a given space X to be a loop space.
description: AMSLATEX, 20 pages
Magnetic fingerprints on the spectra of one-electron and two-electrons interacting in parabolic quantum dots
Creators: name: Mustafa, Omar
name: Odeh, Maen
Publisher: name: arXiv
Year: 2000
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Magnetic fingerprints on the spectra of an interacting electron with a negatively charged ion in a parabolic quantum dot (QD), and of two interacting electrons in such a dot, are investigated via a pseudoperturbative methodical proposal. The effect of ion-electron and electron-electron interactions on the spectra are studied. The effect of the symmetry of such problem is emphasized. Compared to those obtained by Zhu et al. [6], via a series solution, the results are found in excellent accord. Higher excited - states are also reported.
description: Latex file, 26 pages, 7 figures in one ps-file, Submitted for publication
Lobelia minutula Engl.
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Lobelia
Lobelia minutula

description: Lobelia minutula Engl.  —
Habit: Herb.
Habitat: LMWF, LMDF, BZ, UMF, HZ, AZ; 2 300–4 000 m. Distribution: II.
 Voucher: Chogoria Route, Alt. 3050 m, 27 Aug. 1996, Knox 3120 (EA).
References: Fries (1923a), Bussmann (1993, 1994), Agnew (2013).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 89, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
Lobelia telekii Schweinf.
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Lobelia
Lobelia telekii

description: Lobelia telekii Schweinf.  —
Habit: Herb.
Habitat: HZ, AZ, NZ; 2 900–5 000 m. Distribution: IIIa.
 Voucher: Near Lake Michaelson, Alt. 4 112 m, 23 Jan. 2015, SAJIT 002799 (HIB).
 References: Moreau (1944), Rehder et al. (1981), Thulin (1984), Young & Peacock (1985), Blundell (1987), Bussmann (1993, 1994, 2006), Abdi (2013), Agnew (2013).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 89, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
Hawking Radiation for Non-minimally Coupled Matter from Generalized 2D Black Hole Models
Creators: name: Kummer, W.
name: Liebl, H.
name: Vassilevich, D. V.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: It is well known that spherically symmetric reduction of General Relativity (SSG) leads to non-minimally coupled scalar matter. We generalize (and correct) recent results to Hawking radiation for a class of dilaton models which share with the Schwarzschild black hole non-minimal coupling of scalar fields and the basic global structure. An inherent ambiguity of such models (if they differ from SSG) is discussed. However, for SSG we obtain the rather disquieting result of a negative Hawking flux at infinity, if the usual recipe for such calculations is applied.
description: 8 pages