cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effect of lenalidomide on inositide-dependent erythropoiesis and cell cycle in del(5q) myelodysplastic syndromes (mds)
Creators: name: Follo, Matilde Y.
name: Mongiorgi, Sara
name: Finelli, Carlo
name: Clissa, Cristina
name: Quaranta, Marilisa
name: Martini, Désirée
name: Billi, Anna Maria
name: Manzoli, Lucia
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Nuclear Inositide Signalling; Erythroid Differentiation; Cell Cycle.

description: Akt is implicated in erythropoiesis, through PI-PLCgamma1, but is also connected with cell cycle and protein synthesis, via activation of the mTOR pathway (1). Lenalidomide is currently used in the treatment of low-risk MDS patients showing a del(5q) karyotype, as it induces erythropoiesis in non-del(5q) cells and selectively inhibits cell proliferation in del(5q) cells (2). However, the exact molecular mechanisms underlying the effect of Lenalidomide in del(5q) and non-del(5q) MDS cells are still unclear, although Lenalidomide demonstrated an effect on targeting signalling molecules involved in apoptosis, proliferation and differentiation, i.e. Akt (3). Here we analyzed the effect of Lenalidomide on two cell lines: Namalwa CSN.70, bearing a del(5q) karyotype, and U937, with a normal 5q chromosome. In particular, we analyzed several molecules implicated in inositide signalling, such as Akt, mTOR and PI-PLCgamma1, as well as Cyclins and Globin genes, in order to assess the effect of Lenalidomide on cell cycle and erythropoiesis. Moreover, we quantified the gene expression profile of 6 patients diagnosed with del(5q) Low-Risk MDS (IPSS: Low or Int-1) who were given Lenalidomide. In our case series, as well as in cell lines, erythropoiesis activation was associated with a response to Lenalidomide, with an induction of Akt/PLCgamma1 and an increase of Beta-Globin. Moreover, only in non-del(5q) cells, a normal proliferation was allowed, given that del(5q) cells showed a cell cycle arrest and a slight inhibition of the Akt/mTOR pathway, this latter being confirmed also by co-localization experiments performed on primary cells from MDS patients. Therefore, our data support the hypothesis of a specific activation of both inositide-dependent proliferation and erythroid differentiation pathways in response to Lenalidomide treatment in non-del(5q) cells, whereas in the del(5q) cell clone there is a cell cycle arrest and a slower erythroid differentiation. Taken together, these results hint to a specific activation of inositide-dependent signalling pathways during Lenalidomide administration and possibly pave the way to a larger investigation aiming to assess the role of these pathways during the therapy.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
title: ÐÐ¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾-ÑÐ°ÑÑÐ½Ð¾Ðµ Ð¿Ð°ÑÑÐ½ÐµÑÑÑÐ²Ð¾ Ð² Ð¸Ð½Ð½Ð¾Ð²Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÑÐµÑÐµ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÑÐ°ÑÐ½Ð¾ÑÑÐ°Ð½Ð¾Ð²Ð°, ÐÐ½Ð°ÑÑÐ°ÑÐ¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾ â ÑÐ°ÑÑÐ½Ð¾Ðµ Ð¿Ð°ÑÑÐ½ÐµÑÑÑÐ²Ð¾
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Ð¸Ð½Ð½Ð¾Ð²Ð°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÑ
Ð¸Ð½Ð½Ð¾Ð²Ð°ÑÐ¸Ð¸
Ð¸Ð½Ð²ÐµÑÑÐ¸ÑÐ¸Ð¸

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸Ð¸ÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð² Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ²Ð»ÑÐµÑÑÑ ÐÐ§Ð Ð² Ð¸Ð½-Ð½Ð¾Ð²Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÑÐµÑÐµ.
Ð¦ÐµÐ»ÑÑ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼ Ð¸ Ð¾ÑÐµÐ½ÐºÐ° Ð¿Ð¾ÑÐµÐ½ÑÐ¸Ð°Ð»ÑÐ½Ð¾Ð³Ð¾ ÑÐ¾ÑÑÐ° Ð² ÑÑÐµÑÐµ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾-ÑÐ°ÑÑÐ½Ð¾Ð³Ð¾ Ð¿Ð°ÑÑÐ½ÐµÑÑÑÐ²Ð°.
Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ ÐÐ§Ð Ð² Ð¸Ð½Ð½Ð¾Ð²Ð°ÑÐ¸-Ð¾Ð½Ð½Ð¾Ð¹ ÑÑÐµÑÐµ, Ð²ÑÐ´ÐµÐ»ÐµÐ½Ñ Ð½Ð¾ÑÐ¼Ð°ÑÐ¸Ð²Ð½Ð¾-Ð¿ÑÐ°Ð²Ð¾Ð²ÑÐµ Ð°ÑÐ¿ÐµÐºÑÑ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð³Ð¾ÑÑ-Ð´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾-ÑÐ°ÑÑÐ½Ð¾Ð³Ð¾ Ð¿Ð°ÑÑÐ½ÑÑÑÑÐ²Ð° Ð² ÑÑÐ±ÑÐµÐºÑÐ°Ñ Ð Ð¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð¹ Ð¤ÐµÐ´ÐµÑÐ°ÑÐ¸Ð¸, Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¸ Ð¿ÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ñ ÐÐ§Ð Ð² Ð Ð¤.
Ð ÑÐ¾Ð´Ðµ ÑÐ°Ð±Ð¾ÑÑ Ð±ÑÐ»Ð¾ Ð²ÑÑÐ²Ð»ÐµÐ½Ð¾, ÑÑÐ¾ Ð¸Ð½Ð½Ð¾Ð²Ð°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÑÐµÑÐ° Ð½Ð°Ð¸Ð±Ð¾Ð»ÐµÐµ Ð¿ÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ð½Ð° Ð¸ Ð¿Ð¾ÑÑÐ¾Ð¼Ñ ÑÐ²Ð»ÑÐµÑÑÑ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐ¼ Ð¸ÑÑÐ¾ÑÐ½Ð¸ÐºÐ¾Ð¼ ÑÐ¾-ÑÑÐ° ÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð¹ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÐºÐ¸, Ð° Ð²ÑÑÑÐ¿Ð»ÐµÐ½Ð¸Ðµ Ð² ÑÐ¸Ð»Ñ Ð½Ð¾Ð²Ð¾Ð³Ð¾ Ð·Ð°ÐºÐ¾Ð½Ð°, ÑÐµÐ³ÑÐ»Ð¸-ÑÑÑÑÐµÐ³Ð¾ ÐÐ§Ð, Ð´Ð°Ð»Ð¾ ÑÑÐ¸Ð¼ÑÐ» Ð´Ð»Ñ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿ÑÐ¾ÐµÐºÑÐ¾Ð² Ð¸ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ðµ Ð¸Ð½ÑÑÐ¸ÑÑÑÐ¾Ð², ÑÐµÐ»ÑÑ ÐºÐ¾ÑÐ¾ÑÑÑ ÑÐ²Ð»ÑÐµÑÑÑ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ðµ Ð¿Ð°ÑÑÐ½ÐµÑÑÑÐ²Ð° Ð² Ð Ð¾ÑÑÐ¸Ð¸.
Acqua nei sistemi esoplanetari
Creators: Elisa Nichelli
Publisher: name: Media Inaf
Year: 2015

Una ricerca condotta da ricercatori britannici ha rilevato la presenza del 30-35% del contenuto di acqua sulla Terra nell'atmosfera di una nana bianca, dimostrando che l'impatto di comete e asteroidi ricchi di acqua potrebbe essere il canale di trasporto di acqua anche nei sistemi extrasolari
SESAME: La scienza per la pace
Creators: Redazione Media Inaf
Publisher: name: Media Inaf
Year: 2015

È stato presentato all'Università di Roma La Sapienza, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East), un progetto scientifico internazionale per la costruzione, ad Allan, nei pressi di Amman, in Giordania, di una infrastruttura di ricerca basata su una sorgente di luce di sincrotrone di terza generazione, la prima del Medio Oriente
HL Tau nasconde davvero dei pianeti
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2015

Lo scatto risale all'ottobre 2014 quando l'Atacama Large Millimeter/submillimeter Array in Cile ha mostrato dettagli straordinari e mai visti prima nel disco protoplanetario di questo giovane sistema. Animato è sempre stato il dibattito attorno ai cerchi concentrici scuri, che nasconderebbero pianeti in via di formazione
Strategic resource planning of endoscopy services using hybrid modelling for future demographic and policy change
Creators: name: Harper, Alison
name: Mustafee, Navonil
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: For strategic planning of healthcare services, understanding and accounting for future demand can support resource management. A hybrid modelling approach is well-placed to address these issues using demand projections with simulation for capacity planning. We present a methodology which conceptualises each stage as a collaborative activity in a strategic process. Medium-to-long term demand is uncertain, and depends upon internal and external factors. Our novel demand projections use both drivers of internal demand, and environmental scanning to identify external influences on demand. These create demand trajectories for each of three procedures that are used with discrete-event simulation to inform strategic planning for endoscopic diagnostic services. The study involved collaboration with a major Healthcare Trust in England, and demonstrates the applicability of our methodology to support strategic change at the regional service level by aligning external demand with internal resource planning.
Matematica: l’invenzione del mondo
Creators: Davide Coero Borga
Publisher: name: Media Inaf
Year: 2015

Finalista al Premio Galileo 2015, “Dimostrare l’impossibile” è il racconto diverso e originale della storia dell’impresa scientifica e del pensiero scientifico: protagonisti i matematici, che spesso trovano cose che non stanno cercando perché queste, ancora, non esistono
Enumerating and identifying semiperfect colorings of symmetrical patterns
Creators: name: Felix, Rene P.
name: Loquias, Manuel Joseph C.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Combinatorics (math.CO)
subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 05B45; 52C20; 20H15; 20B99

description: If $G$ is the symmetry group of an uncolored pattern then a coloring of the pattern is semiperfect if the associated color group $H$ is a subgroup of $G$ of index 2. We give results on how to identify and enumerate all inequivalent semiperfect colorings of certain patterns. This is achieved by treating a coloring as a partition $\{hJ_iY_i:i\in I,h\in H\}$ of $G$, where $H$ is a subgroup of index 2 in $G$, $J_i\leq H$ for $i\in I$, and $Y=\cup_{i\in I}{Y_i}$ is a complete set of right coset representatives of $H$ in $G$. We also give a one-to-one correspondence between inequivalent semiperfect colorings whose associated color groups are conjugate subgroups with respect to the normalizer of $G$ in the group of isometries of $\mathbf{R}^n$.
description: 13 pages, 6 figures
Injectable pulsatile drug delivery hydrogels: how do we get to the clinic?
Creators: name: Baker, Kayla
name: Hoare, Todd
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mental Health
subject: Hematology

description: Injectable pulsatile drug delivery hydrogels: how do we get to the clinic?
Single photo and electroproduction of pions at EBAC@JLAB
Creators: name: Julia-Diaz, B.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Within the Excited Baryon Analysis Center we have performed a dynamical coupled-channels analysis of the available $p(e,e' π)N$ data in the region of $W \leq $ 1.6 GeV and $Q^2 \leq$ 1.45 (GeV/c)$^2$. The channels included are $γ^* N$, $πN$, $ηN$, and $ππN$ which has $πΔ$, $ρN$, and $σN$ components. With the hadronic parameters of the model determined in our previous investigations of $πN\to πN$ reaction, we have found that the available data in the considered $W \leq $ 1.6 GeV region can be fitted well by only adjusting the bare $γ^* N \to N^*$ helicity amplitudes for the lowest $N^*$ states in $P_{33}$, $P_{11}$, $S_{11}$ and $D_{13}$ partial waves. The meson cloud effect, as required by the unitarity conditions, on the $γ^* N \to N^*$ form factors are examined.
description: 6 pages, invited talk at NSTAR 2009, Beijing (China), 2009, to appear in the proceedings
15 milioni per la sfida dei Big Data
Creators: Ufficio stampa Inaf
Publisher: name: Media Inaf
Year: 2015

Il progetto contribuirà a risolvere le sfide dei “Big Data” che l'astronomia europea sta affrontando e permetterà di dare al pubblico un accesso interattivo diretto ad alcune delle migliori immagini astronomiche in Europa reso possibile con il finanziamento di 15 milioni di Euro assegnato dall’Unione Europea al progetto ASTERICS (ASTronomy ESFRI and Research Infrastructure CluSter)
Effect of extracellular matrix components on the expression of epithelial-to-mesenchymal transition markers in cultured human pancreatic ductal adenocarcinoma cells
Creators: name: Gagliano, Nicoletta
name: Tacchini, Lorenza
name: Valerio, Vincenza
name: Celesti, Giuseppe
name: Laghi, Luigi
name: Procacci, Patrizia
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Epithelial-to-mesenchymal transition; tumor microenvironment; pancreatic ductal adenocarci¬noma; matrix metalloproteinases.

description: Epithelial-to-mesenchymal transition (EMT) is a step-wise process leading to the phenotypic switch of epithelial to mesenchymal cells, providing these cells with a metastatic phenotype. During EMT epithelial cells loose adhesion by down regulation of E-cadherin and express N-cadherin, display cytoskeleton reorganization by expressing vimentin and α-smooth muscle actin (αSMA), acquire motile properties and become invasive by secretion of matrix metalloproteinases (MMPs). Cancer cell phenotype is influenced by the tumor microenvironment in relation to tumor progression, as well as to cell proliferation and invasion. The role of the extracellular matrix (ECM) in the microenvironment is particularly relevant in pancreatic ductal adenocarcinoma (PDAC) since this carcinoma is characterized by an intense desmoplastic reaction, representing the environment where the complex interplay between tumor cells, stromal fibroblasts and ECM components occurs. We aimed at analyzing in vitro the effect of the crosstalk between PDAC cells and their microenvironment by characterizing PDAC cell phenotype in cells cultured on different ECM proteins used as a substrate, in order to better understand the relationship between cancer cell behaviour and the proteins occurring in the desmoplastic tissue. We analyzed by immunofluorescence the expression of the main EMT markers such as E-cadherin, N-cadherin, β-catenin, αSMA, vimentin and collagen type I (COL-I) in PDAC cells cultured on laminin, fibronectin, COL-I and without coating (NC). Moreover, we investigated cell proliferation and MMPs activity in cell culture supernatants by SDS-zymography. Cell morphology was similar in PDAC cells cultured on laminin, fibronectin, COL-I, and in NC, as well as the E-cadherin/β-catenin complex, αSMA and COLI expression; by contrast, vimentin was undetectable in all the experimental conditions. N-cadherin was slightly detectable in cells cultured on fibronectin, COL-I, and laminin, and at lower extent in NC cells. Cell proliferation resulted similar in NC and in cells cultured on fibronectin, decreased on laminin and increased on COL-I. MMP-9 activity exhibited a similar trend, resulting similar on fibronectin, decreased on laminin and stimulated on COL-I. These preliminary results provide new insights in the characterization of the mutual effects elicited by the tumor-stroma interplay on the cancer cell, and will contribute to better understand the influence of the stroma on PDAC cancer cell phenotype, in order to develop new therapeutic strategies.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Ventilator-Induced Lung injury: a preliminary morphological study
Creators: name: Gagliano, Nicoletta
name: Amini, Martina
name: Valerio, Vincenza
name: Aricò, Roberta
name: Chiurazzi, Chiara
name: Gotti, Miriam
name: Cressoni, Massimo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Ventilator-Induced Lung injury; collagen; elastin.

description: In this study we aimed at characterizing by morphological methods the effect of ventilator-induced lung injury (VILI) on lung structure, and we analyzed collagen and elastin content to understand the possible role of the main components of lung connective tissue in the development of VILI. For this purpose four female piglets (21.7±4.5 kg) were sedated, intubated and mechanically ventilated with high pressure to induce VILI. After death, lungs were excised inflated; each lung was divided in four regions, and lung fragments were obtained from each region of both lungs: three samples from subpleural regions, one sample from the medial portion of the lung. Lung fragments were immediately fixed in 4% formalin in 0.1M phosphate buffered saline (PBS), pH 7.4, routinely dehydrated, paraffin embedded, and serially cut (thickness 5 μm). Lung structure was analyzed in haematoxylin-eosin stained sections using a semiquantitative grading scale to assess the injury grade. To study collagen and elastin content, sections were stained by Sirius red and Weigert’s resorcin-fuchsin, respectively, and analyzed by a specific software. Collagen and elastin content were expressed as a percent of the stained area relative to the lung tissue. Light microscopy analysis of hematoxylin-eosin stained sections revealed that VILI induced several lung injuries such as hyaline membranes, interstitial and septal infiltrate, vascular congestion and intra-alveolar hemorraging, alveoli rupturing and basophilic material deposition. These lesions were diffuse and involved the whole lung parenchyma without any preferential localization. Image analysis of Sirius red and Weigert’s resorcin-fuchsin stained sections showed that lung injury was more evident where elastin was less abundant, but was also evident where elastin content was high and collagen was concomitantly less abundant. These preliminary data suggest that lung extracellular matrix could influence the response to damaging ventilation, and that both
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Topological Casimir effect in nanotubes and nanoloopes
Creators: name: Saharian, A. A.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The Casimir effect is investigated in cylindrical and toroidal carbon nanotubes within the framework of the Dirac-like model for the electronic states. The topological Casimir energy is positive for metallic cylindrical nanotubes and is negative for semiconducting ones. The toroidal compactification of a cylindrical nanotube along its axis increases the Casimir energy for metallic-type (periodic) boundary conditions along its axis and decreases the Casimir energy for the semiconducting-type compactifications. For finite length metallic nanotubes the Casimir forces acting on the tube edges are always attractive, whereas for semiconducting-type ones they are attractive for small lengths of the nanotube and repulsive for large lengths.
description: 5 pages, 1 figure, Contribution to Proceedings of QFEXT09, 21-25 September 2009, Oklahoma, USA
On the uniqueness of multiple trigonometric series
Creators: name: Cross, George Elliot
Publisher: name: University of British Columbia
Year: 2012

description: The multiple trigonometric series ∑ c(m) exp(i(m,x)), where m = (m₁, ... ,m(n)), x = (x₁, …x(n)), (m,x) = m₁^x₁+ ...+ m(n) x(n), and m(j) ≥ 0, is said to be summable (T,k) if the series [symbol omitted] C(p) (x) is summable (C,k) where C(p)(x) denotes the triangular sum ∑c(m)exp(i(m,x)), m₁ + ... + m(n) = p. The series is said to be bounded (T,k) if the series [symbol omitted] C(p)(x) is bounded (C,k). Using the fact that the triangular summation of the multiple trigonometric series considered is equivalent to the Cesàro summation of a single series of a particular form, this thesis obtains uniqueness theorems for multiple trigonometric series by first proving the required theorems for the single series. It is shown that if the series [symbol omitted] c(n) exp(int) is summable (C,k) then the coefficients c(n) are given in terms of the [formula omitted] - integral defined by James [Trans. Amer. Math. Soc. vol. 76 (1954) pp.149-176, section 8]. When the series is bounded (C,k) a Fourier representation is obtained in terms of Burkill's C(k+1)P - integral [Proc. London Math. Soc. (2) vol. 39 (1935) pp. 541-552]. It is shown that if f(t) is periodic and C(r)P - integrable, then the C(r)P - (definite) integral is a constant multiple of the [formula omitted] - (definite) integral of f(x). This gives a Fourier representation of the coefficients in terms of the [formula omitted] - integral when the series is bounded (C,k). These results are then extended to multiple trigonometric series. A representation for the coefficients in terms of the C(k+1)P - integral is demonstrated if the series is bounded (T,k). Finally a uniqueness theorem is proved where the summability set is a countable set of n - tuples of the form (x₁₀,x₂₀, …,x(n)-₁₀,x(ni), for fixed x₁₀x₂₀,…,x(n)₋₁₀, and I = 1,2,3,… .
[RAiD advisory group meeting] GraspOS overview
Creators: name: Tatum, Clifford
Publisher: name: Zenodo
Year: 2023

description: Presentation of the GraspOS project at the RAiD advisory group meeting on 20 Ocotber 2023, in Salzburg, Austria.

This presentation focuses on introducing the project and presenting the OSAF, the Open and Federated Research Assessment Infrastructure and the pilots.
All’Expo la finale di Famelab Italia
Creators: Redazione Media Inaf
Publisher: name: Media Inaf
Year: 2015

Sarà il Centro Conferenze della manifestazione milanese l’arena sulla quale si sfideranno, sotto le telecamere del programma Nautilus della RAI, i 14 concorrenti della gara nazionale di Famelab, l’X-Factor della scienza. Il vincitore rappresenterà l’Italia alla finale mondiale
PKCε regulates vessel formation by peri-vascular adipose tissue (PVAT) cells
Creators: name: Galli, D.
name: Carubbi, C.
name: Masselli, E.
name: Queirolo, V.
name: Bucci, G.
name: Mirandola, P.
name: Gobbi, G.
name: Vitale, M.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Peri-vascular adipose tissue (PVAT); vascular progenitors; PKCε.

description: Vessel formation is crucial in tumour growth and tissue regeneration. Protein kinase C (PKC) ε has a well-known role on hematopoietic and mesenchymal progenitor cell differentiation and proliferation (Gobbi et al. 2013). Although PKCε has a demonstrated role in vascular restenosis, data on PKCε and vascular progenitor differentiation are still lacking. The aim of this work was to study the role of PKCε in vessel formation by adult adipose tissue cell progenitors. We, first, isolated the vessel progenitors from the adipose tissue localized between aortic arch and pulmonary artery of adult mice by collagenase/elastase digestion followed by magnetic immunoselection of Sca1+ cells (Passmann et al. 2008). We, then, tested their capability to form vessels in collagen gels and to differentiate to endothelial and smooth muscle lineage after treatment with PKCε specific activator and inhibitor peptides. The functional experiments showed that the pharmacological activation of endogenous PKCε abrogated tubule formation with a concomitant decrease of smooth alpha-actin (SMA) and platelet endothelial cell adhesion molecule (PECAM) together with the up-regulation of p-PAK1 expression. In vivo transient over-expression of PKCε significantly reduced SMA and PECAM expression levels in vessel wall cells. Together our data suggests that PKCε may affect vessel wall remodelling balancing the “phenotypic switching” (Salmon et al. 2013) between the proliferative and the differentiated state of smooth muscle and endothelial progenitor mesenchymal cells.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
La galassia più distante mai osservata
Creators: Corrado Ruscica
Publisher: name: Media Inaf
Year: 2015

Si chiama EGS-zs8-1 ed è un oggetto particolarmente brillante che si trova ad un'epoca in cui l'Universo aveva soltanto 670 milioni di anni dopo il Big Bang. I risultati di questo studio, ottenuti con lo spettrometro MOSFIRE installato presso il telescopio Keck-I e pubblicati su Astrophysical Journal Letters, forniscono nuovi indizi sulle galassie massicce primordiali che sono esistite durante il periodo della reionizzazione
Choosing where to set the threshold between low- and high-risk patients: Evaluating a classification tool within a simulation
Creators: name: Saville, Christina E.
name: Smith, Honora K.
name: Bijak, Katarzyna
name: Leonard, Pauline
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Health service providers must balance the needs of high-risk patients who require urgent medical attention against those of lower-risk patients who require reassurance or less urgent medical care. Based on their characteristics, we developed a tool to classify patients as low- or high-risk, with correspondingly different patient pathways through a service. Rather than choosing the threshold between low- and high-risk patients solely considering classification accuracy, we demonstrate the use of discrete-event simulation to find the best threshold from an operational perspective as well. Moreover, the predictors in classification tools are often categorical, and may be inter-dependent. Defining joint distributions of these variables from empirical data assumes that missing combinations are impossible. Our new approach involves using Poisson regression to estimate the joint distributions in the underlying population. We demonstrate our methods on a practical example: setting the threshold between low- and high-risk patients with proposed different pathways through a breast diagnostic clinic.
Acqua salmastra su Marte
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2015

Sul pianeta rosso c'è acqua, ormai le conferme arrivano di giorno in giorno. Ma quest'acqua può essere alla base della vita sul quarto pianeta del Sistema solare? C'è mai stata vita su Marte? I ricercatori hanno scoperto che in alcuni momenti dell'anno dell'acqua salmastra arriva in superficie allo stato liquido
A remark on the Mahler conjecture: local minimality of the unit cube
Creators: name: Nazarov, Fedor
name: Petrov, Fedor
name: Ryabogin, Dmitry
name: Zvavitch, Artem
Publisher: name: arXiv
Year: 2009
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 52A15, 52A21

description: We prove that the unit cube $B^n_{\infty}$ is a strict local minimizer for the Mahler volume product $vol_n(K)vol_n(K^*)$ in the class of origin symmetric convex bodies endowed with the Banach-Mazur distance.
Functionally differentiated cardiomyocites derived from human amniotic fluid-derived stem cells
Creators: name: Ghinassi, Barbara
name: D’Amico, Maria Angela
name: Izzicupo, Pascal
name: Bascelli, Adriana
name: Antonucci, Ivana
name: Stuppia, Liborio
name: Di Baldassarre, Angela
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Cardiomyocites; Amniotic fluid stem cells; cardiac differentiation.

description: Purpose. Human amniotic fluid-derived stem cells (hAFSC) are multipotent stem cells sharing characteristics of both embryonic and adult stem cells. It has been already reported that hAFSC can differentiate toward cardiac lineage though the embryonic body (EB) formation, but the 3D structure and cellular heterogeneity of EB represent an important limitation. Aim of this study was to fully differentiate the hAFSC overcoming the EB limitations. Methods. hAFSC were obtained from normal amniocentesis. Cells cultured in monolayer were exposed sequentially to Ascorbic Acid, 5-Azacytidine, BMP4, ActivinA, VEGF up to 20 days. Differentiation was evaluated monitoring by Western Blot, immunofluorescent and cytometric analyses the expression of CD90, as mesenchymal stem cell marker, and of Nkx2.5, Gata4, sarcomeric α-actinin (αSA), α cardiac myosin heavy chain (αMHC), cardiac T-troponin (TnT)and Connexin43 as cardiac markers. Results. During the differentiation cultures cells underwent a progressive decrease of CD90 accompanied by the induction cardiac markers. After 15 days we evidenced that almost the entire cell population was positive for αMHC, αSA cTnT and Connexin 43 expressions (Table I); moreover, even if the % of Gata4+ and Nkx2.5+ cells did not varied during the culture, a significant increase of Nkx2.5 nuclear translocation (9.1±0.9% vs 18.0±1.8% Nkx2.5 nuclear positive cells in hAFSC and differentiated cells respectively, p<.005, analysis by ImageStream) was detected. Some small beating foci (about 8-10% of the plate) were also observed. Conclusion. We demonstrate that hAFSC can fully differentiate into myocytes giving rise to a homogenous population with cardiac-specific molecular and functional properties.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Geometric consistency index for interval pairwise comparison matrices
Creators: name: Tu, Jiancheng
name: Wu, Zhibin
name: Xu, Jiuping
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: Interval pairwise comparison matrices are widely accepted for practical decision making problems when the decision maker is unable to provide an exact judgment on the alternatives. However, as measuring the preference consistencies in pairwise comparison decision making problems is important, this paper proposes a new interval pairwise comparison matrix consistency measure, the average geometric consistency index, that assumes that the preference in a given interval follows the lognormal distribution. This geometric consistency measure accounts for the interval boundaries and uncertainties. As it is often difficult to rationally rank alternatives when interval pairwise comparison matrices are highly uncertain and/or inconsistent, we propose an optimization model to reduce the inconsistencies of these matrices while minimizing information loss and controlling uncertainties. An interval priority vector is derived to rank the alternatives. The feasibility and efficiency of the models are demonstrated using numerical examples.
Manufacturer rebate strategy under chain to chain competition
Creators: name: He, Haojia
name: Ai, Xingzheng
name: Wang, Ganfu
name: Zhong, Li
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: This article builds an analytical framework for manufacturers developing rebate strategies under the chain to chain competition. We demonstrate that rebates are likely to be implemented by manufacturers in both more cost-effective and less cost-effective business environments. We show that manufacturers are more likely to use more cost-effective rebates than less cost-effective rebates when the price competition between two chains is intensified. Rebate can be a dominant strategy for both manufacturers and retailers under two conditions: the market with a small percentage of the rebate-sensitive segment, plus (1) fierce competition and more cost-effective rebates, or plus (2) less cost-effective rebates. Our research provides a reference frame to design price discrimination mechanisms and some management insights for manufacturers.
The role of CDK9 in myogenesis
Creators: name: Giacinti, C.
name: Chiandotto, S.
name: Tomei, V.
name: Candolfi, N.
name: Molinaro, M.
name: Vivarelli, E.
name: Musarò, A.
name: Giordano, A.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Skeletal muscle differentiation; myogenesis; cdks.

description: Cdk9 is a member of cyclin-dependent kinases (cdks). It is expressed in human and murine tissues with high levels in terminally differentiated cells. It is involved in the regulation of transcriptional elongation via phosphorylation of CTD of RNA polII (1). It has been demonstrated that CdK9, complexed with CyT2a, plays a role in the activation of myogenic program. Moreover Cdk9-CyT2a activity is not down-regulated in myotube formation, but its activation contributes to the transcriptional activity MyoD-mediated during myogenic program (2). Recently, a 55 kDa protein called cdk9-55 has been identified. Cdk9-55 is significantly upregulated in cells induced to differentiate, either in C2C12 cells or in satellite isolated cells. In addition, it has been demonstrated that there is a clear induction of cdk9-55 expression in injured skeletal muscles (3). In order to deepen the discussion and extend the understanding of the biological role of the two isoforms of cdk9 during skeletal muscle differentiation process, we report the role of the two isoforms during in vivo mouse myogenesis. We have analyzed the behavior of CDk9-42 and CDK9-55 in primary and secondary myogenesis. Of particular interest are the apparent inverse correlation between the two cdk9 isoforms during the events of limbs formation and how the expression of two CDK9 isoforms, in combination with specific positive (Cycline T1,T2,k) or negative regulators (7SKsnRNA/Hexim1), is associated to a specific cellular phenotype and correlated to a specific function.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Wavelet domain Bayesian denoising of string signal in the cosmic microwave background
Creators: name: Hammond, D. K.
name: Wiaux, Y.
name: Vandergheynst, P.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: An algorithm is proposed for denoising the signal induced by cosmic strings in the cosmic microwave background (CMB). A Bayesian approach is taken, based on modeling the string signal in the wavelet domain with generalized Gaussian distributions. Good performance of the algorithm is demonstrated by simulated experiments at arcminute resolution under noise conditions including primary and secondary CMB anisotropies, as well as instrumental noise.
description: 16 pages, 11 figures. Version 2 matches version accepted for publication in MNRAS. Changes include substantial clarifications on our approach and a significant reduction of manuscript length
title: ÐÐ¾Ð»Ð½Ð¾Ð²Ð¾Ðµ Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ðµ Ð³Ð°Ð·Ð° Ð² Ð¿ÑÐ¾ÑÑÐ¶ÐµÐ½Ð½ÑÑ ÐºÐ°Ð½Ð°Ð»Ð°Ñ
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÑÐ»Ð¾Ð²Ð¸Ñ, Ð¡ÐµÑÐ³ÐµÐ¹
name: ÐÐ¸ÐºÐ¾Ð»Ð°Ð¹Ð½ÐµÐ½, ÐÐ¸ÐºÑÐ¾Ñ
Publisher: name: ÐÐ·Ð´-Ð²Ð¾ ÐÐ¾Ð»Ð¸ÑÐµÑÐ½. ÑÐ½-ÑÐ°
Year: 2006
Subjects: ÐÐ°Ð·Ñ

description: Ð£ÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²ÑÐµÑ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð¼Ñ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾Ð¼Ñ ÑÑÐ°Ð½Ð´Ð°ÑÑÑ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ¾Ð¹ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ 140500 "Ð­Ð½ÐµÑÐ³Ð¾Ð¼Ð°ÑÐ¸Ð½Ð¾ÑÑÑÐ¾ÐµÐ½Ð¸Ðµ" (ÑÐ¿ÐµÑÐ¸Ð°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ 140501 "ÐÐ²Ð¸Ð³Ð°ÑÐµÐ»Ð¸ Ð²Ð½ÑÑÑÐµÐ½Ð½ÐµÐ³Ð¾ ÑÐ³Ð¾ÑÐ°Ð½Ð¸Ñ") Ð¸ 010600 "ÐÑÐ¸ÐºÐ»Ð°Ð´Ð½ÑÐµ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÐºÐ° Ð¸ ÑÐ¸Ð·Ð¸ÐºÐ°". ÐÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð¾ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² ÑÐµÑÐ²ÐµÑÑÐ¾Ð³Ð¾, Ð¿ÑÑÐ¾Ð³Ð¾ Ð¸ ÑÐµÑÑÐ¾Ð³Ð¾ ÐºÑÑÑÐ¾Ð² ÑÐ½ÐµÑÐ³Ð¾Ð¼Ð°ÑÐ¸Ð½Ð¾ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð¸ ÑÐ¸Ð·Ð¸ÐºÐ¾-Ð¼ÐµÑÐ°Ð½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ°ÐºÑÐ»ÑÑÐµÑÐ¾Ð², Ð¸Ð·ÑÑÐ°ÑÑÐ¸Ñ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½Ñ "Ð¢ÐµÐ¾ÑÐ¸Ñ Ð³Ð°Ð·Ð¾Ð¾Ð±Ð¼ÐµÐ½Ð° Ð² Ð´Ð²Ð¸Ð³Ð°ÑÐµÐ»ÑÑ" Ð¸ "ÐÐ¸Ð½Ð°Ð¼Ð¸ÐºÐ° Ð²ÑÐ·ÐºÐ¾Ð³Ð¾ Ð³Ð°Ð·Ð°" Ð² ÑÐ°Ð¼ÐºÐ°Ñ Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ¾Ð¹ Ð¸ Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ¾Ð¹ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²Ð¾Ðº. Ð Ð°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÑÑÑÑ Ð½ÐµÑÑÐ°ÑÐ¸Ð¾Ð½Ð°ÑÐ½ÑÐµ Ð¿ÑÐ¾ÑÐµÑÑÑ Ð² Ð¿Ð¾ÑÐ¾ÐºÐµ Ð³Ð°Ð·Ð° Ð¿ÑÐ¸ ÐµÐ³Ð¾ Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ð¸ Ð² Ð¿ÑÐ¾ÑÑÐ¶ÐµÐ½Ð½ÑÑ ÐºÐ°Ð½Ð°Ð»Ð°Ñ. Ð§Ð¸ÑÐ»ÐµÐ½Ð½ÑÐµ Ð¾ÑÐµÐ½ÐºÐ¸ ÑÐ²Ð»ÐµÐ½Ð¸Ð¹ Ð±Ð°Ð·Ð¸ÑÑÑÑÑÑ Ð½Ð° Ð´Ð²ÑÐ¼ÐµÑÐ½Ð¾Ð¹ Ð½ÐµÑÑÐ°ÑÐ¸Ð¾Ð½Ð°ÑÐ½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ðµ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ð¹ Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ Ð¸ ÑÐ½ÐµÑÐ³Ð¸Ð¸, Ð·Ð°Ð¿Ð¸ÑÐ°Ð½Ð½ÑÑ Ð² Ð¿ÑÐ¸Ð±Ð»Ð¸Ð¶ÐµÐ½Ð¸Ð¸ Â«ÑÐ·ÐºÐ¾Ð³Ð¾ ÐºÐ°Ð½Ð°Ð»Ð°Â» Ð² Ð´Ð¸Ð²ÐµÑÐ³ÐµÐ½ÑÐ½Ð¾Ð¹ ÑÐ¾ÑÐ¼Ðµ. ÐÐ·Ð»Ð°Ð³Ð°ÑÑÑÑ Ð¼ÐµÑÐ¾Ð´Ñ ÑÐ¸ÑÐ»ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¸Ð½ÑÐµÐ³ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ð¹, ÑÐ¾ÑÑÐ°Ð½ÑÑÑÐ¸Ðµ ÑÐ²Ð¾Ð¹ÑÑÐ²Ð° ÐºÐ¾Ð½ÑÐµÑÐ²Ð°ÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¿Ð¾ÑÐ¾ÐºÐ°. ÐÐ°ÐµÑÑÑ Ð¿Ð¾ÑÑÐ°Ð½Ð¾Ð²ÐºÐ° Ð¸ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ ÑÐµÑÐµÐ½Ð¸Ñ ÑÑÐ´Ð° Ð·Ð°Ð´Ð°Ñ, Ð¸Ð¼ÐµÑÑÐ¸Ñ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð·Ð½Ð°ÑÐµÐ½Ð¸Ðµ
description: ÐÐµÑÐ°ÑÐ°ÐµÑÑÑ Ð¿Ð¾ ÑÐµÑÐµÐ½Ð¸Ñ ÑÐµÐ´Ð°ÐºÑÐ¸Ð¾Ð½Ð½Ð¾-Ð¸Ð·Ð´Ð°ÑÐµÐ»ÑÑÐºÐ¾Ð³Ð¾ ÑÐ¾Ð²ÐµÑÐ° Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¾Ð³Ð¾ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑÐ°.
Backbone of complex networks of corporations: The flow of control
Creators: name: Glattfelder, J. B.
name: Battiston, S.
Publisher: name: arXiv
Year: 2009
Subjects: subject: General Finance (q-fin.GN)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Economics and business
subject: FOS: Physical sciences

description: We present a methodology to extract the backbone of complex networks based on the weight and direction of links, as well as on nontopological properties of nodes. We show how the methodology can be applied in general to networks in which mass or energy is flowing along the links. In particular, the procedure enables us to address important questions in economics, namely, how control and wealth are structured and concentrated across national markets. We report on the first cross-country investigation of ownership networks, focusing on the stock markets of 48 countries around the world. On the one hand, our analysis confirms results expected on the basis of the literature on corporate control, namely, that in Anglo-Saxon countries control tends to be dispersed among numerous shareholders. On the other hand, it also reveals that in the same countries, control is found to be highly concentrated at the global level, namely, lying in the hands of very few important shareholders. Interestingly, the exact opposite is observed for European countries. These results have previously not been reported as they are not observable without the kind of network analysis developed here.
description: 24 pages, 12 figures, 2nd version (text made more concise and readable, results unchanged)
A view to the future: standardizing 3D-3D superimposition for identification from next generation video surveillance systems
Creators: name: Gibelli, D.
name: De Angelis, D.
name: Poppa, P.
name: Cappella, A.
name: Cattaneo, C.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Forensic anthropology; personal identification; videosurveillance system; stereophotogramme¬try.

description: The identification of culprits from videosurveillance systems brings about relevant problems for what concerns the reliability of comparison and quantification of the degree of match between the culprit and the suspect. The actual videosurveillance give only 2D images of the culprit, which can be compared to a 3D model of the suspect’s face in 2D-3D superimposition. However, in the next future the videosurveillance systems will provide a 3D image of the filmed persons, which may allow the operator to perform 3D-3D superimposition. This study aims at exposing a pilot study based on 10 male subjects: the face from each individual underwent two acquisitions by stereophotogrammetry. On each 3D facial model, 9 landmarks (right and left: en, ex, ch: midline: se, gn, prn) were identified by VAM® software; the acquisitions of each individual were then superimposed with the models of all the other subjects in order to reduce the distance between the corresponding points. The RMS value (Root Mean Square) between the two models was then calculated. When the two superimposed models belonged to the same individual, RMS value was in mean 1.58 mm (SD: 0.61 mm), whereas when the two models were taken from different persons, the same value was 4.54 mm (SD: 2.02 mm) with a statistically significant (p<0.0001). This pilot study shows that the judgment of identification based on 3D-3D superimposition may provide reliable results. The improvement specific methods of 3D-3D comparison may provide in the next future relevant advantages in this field of forensic anthropology.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
La pulsar binaria con l’orbita più larga
Creators: Stefano Parisini
Publisher: name: Media Inaf
Year: 2015

Durante un campo estivo, una coppia di studenti statunitensi delle scuole superiori hanno scoperto un’altra straordinaria coppia: la pulsar che orbita più lontano da una stella di neutroni compagna. Il commento di Marta Burgay dell’INAF
Resources Required for Topological Quantum Factoring
Creators: name: Baraban, M.
name: Bonesteel, N. E.
name: Simon, S. H.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We consider a hypothetical topological quantum computer where the qubits are comprised of either Ising or Fibonacci anyons. For each case, we calculate the time and number of qubits (space) necessary to execute the most computationally expensive step of Shor's algorithm, modular exponentiation. For Ising anyons, we apply Bravyi's distillation method [S. Bravyi, Phys. Rev. A 73, 042313 (2006)] which combines topological and non-topological operations to allow for universal quantum computation. With reasonable restrictions on the physical parameters we find that factoring a 128 bit number requires approximately 10^3 Fibonacci anyons versus at least 3 x 10^9 Ising anyons. Other distillation algorithms could reduce the resources for Ising anyons substantially.
description: 4+epsilon pages, 4 figures
Esopianeti: un gigante anomalo
Creators: Davide Coero Borga
Publisher: name: Media Inaf
Year: 2015

Dalle dimensioni paragonabili al nostro Giove, ruota in orbita stretta attorno a una piccola stella, 500 anni luce da qui: si tratta di un pianeta formatosi chissà dove e aggiuntosi in un secondo tempo al lontano sistema stellare. Ma per i ricercatori non c’è spiegazione
A novel method of morphological and metrical assessment by 3D-3D superimposition for the assessment of facial mimicry: a pilot study
Creators: name: Gibelli, D.
name: De Angelis, D.
name: Poppa, P.
name: Cappella, A.
name: Cattaneo, C.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Anatomy; facial mimicry; stereophotogrammetry; RMS (Root Mean Square).

description: The assessment of facial mimicry has a relevant importance not only in anatomy, but also in clinics for the evaluation of facial performances in patients affected by neurological or muscular impairments, and in forensic medicine, for the standardization of individualizing markers useful for personal identification. The application of modern 3D image acquisition systems may provide reliable results, especially for what concerns the analysis of facial surfaces: however, the comparison of anatomical structures needs standardized, reproducible protocols in order to provide comparable data. This study aims at exposing a novel and promising method for comparing 3D profiles, useful for quantifying alteration of facial structures in different conditions. Ten male adults, aged between 30 and 40 years underwent to four acquisitions by stereophotogrammetry (VECTRA-3D®: Canfield Scientific, Inc., Fairfield, NJ) with different expressions (neutral, happy, sad, angry, surprised). On each 3D facial model, 9 landmarks (right and left endocanthion, exocanthion, cheilion: on the midline, selion, pronasale, subnasale) were identified using VAM® software; the acquisition of each individual performed with happy, sad, angry and surprised expression was then superimposed to the neutral one, in order to reach the best match between the corresponding landmarks. This procedure allowed the operator to obtain also a chromatic sheet of the face, where in blue are colored the growing zones and in red the zones which showed a decrease. In all the cases, the RMS value (Root Mean Square) between the two models was calculated as well. The highest difference in comparison with the neutral standard was shown by the happy expression (mean RMS 4.11 mm, SD 1.13 mm), followed by the surprised expression (mean RMS 2.74 mm, SD 1.02 mm) and the sad (mean RMS 1.3 mm, SD 0.49 mm) and angry ones (mean RMS 1.21 mm, SD 0.37 mm). The happy and surprised expressions showed a wide modification of the mouth, chin and cheek regions, whereas the sad and angry expressions were affected by slight and more variable alterations. This pilot study shows that the 3D-3D superimposition may provide reliable results concerning facial alteration due to mimicry, which may be useful for clinical purposes: further studies are needed in order to test the variability of morphological and metrical parameters according to age and sex.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Asteroidi killer ed eruzioni vulcaniche
Creators: Elisa Nichelli
Publisher: name: Media Inaf
Year: 2015

Uno studio guidato da scienziati dell'Università della California suggerisce che l'impatto avvenuto oltre 60 milioni di anni fa al largo della penisola dello Yucatan potrebbe aver innescato le massicce eruzioni di lava del Deccan, in India
Gowdy waves as a test-bed for constraint-preserving boundary conditions
Creators: name: Bona, C.
name: Bona-Casas, C.
Publisher: name: arXiv
Year: 2009
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Gowdy waves, one of the standard 'apples with apples' tests, is proposed as a test-bed for constraint-preserving boundary conditions in the non-linear regime. As an illustration, energy-constraint preservation is separately tested in the Z4 framework. Both algebraic conditions, derived from energy estimates, and derivative conditions, deduced from the constraint-propagation system, are considered. The numerical errors at the boundary are of the same order than those at the interior points.
description: 5 pages, 1 figure. Contribution to the Spanish Relativity Meeting 2009
Buchi neri molto ‘golosi’
Creators: Corrado Ruscica
Publisher: name: Media Inaf
Year: 2015

Gli astronomi hanno trovato una popolazione di buchi neri caratterizzati da uno spesso disco di accrescimento. L'analisi dei dati suggerisce che questi oggetti, chiamati quasar, stanno consumando una quantità enorme di materia ad un ritmo straordinario. I risultati di questo studio, pubblicati su Astrophysical Journal, potranno fornire nuovi indizi sull'evoluzione dei buchi neri supermassicci che sono esistiti duranti le fasi primordiali della storia dell'Universo
title: ÐÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ ÑÑÐ°Ð½ÑÐ°Ð¹Ð·Ð¸Ð½Ð³Ð¾Ð²Ð¾Ð³Ð¾ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ Â«Ð¡Ð¢Ð Â«ÐÐµÑÑÐ¾Ð²Ð¸ÑÂ»Â»
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°Ð»Ð¸Ð½Ð¸Ð½, ÐÐ²Ð³ÐµÐ½Ð¸Ð¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÑÑÐ°Ð½ÑÐ°Ð¹Ð·Ð¸Ð½Ð³
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description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ Ð¡ÑÑÐ¾Ð¸ÑÐµÐ»ÑÐ½ÑÐ¹ ÑÐ¾ÑÐ³Ð¾Ð²ÑÐ¹ Ð´Ð¾Ð¼ Â«ÐÐµÑÑÐ¾Ð²Ð¸ÑÂ».
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