Additional file 1 of Helicobacter pylori seropositivity associates with hyperglycemia, but not obesity, in Danish children and adolescents
Creators: name: Kløve, Sigri
name: Stinson, Sara E.
name: Romme, Fie O.
name: Butt, Julia
name: Graversen, Katrine B.
name: Lund, Morten A. V.
name: Fonvig, Cilius E.
name: Waterboer, Tim
name: Perez-Perez, Guillermo I.
name: Hansen, Torben
name: Holm, Jens-Christian
name: Andersen, Sandra B.
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Fig. S1. Helicobacter pylori seropositivity (%) in three different age groups. Table S1. Descriptive characteristics of the study population stratified by cohort. Table S2. Multiplex serology Helicobacter pylori antigens and antigen-specific cut-offs at 1:100 serum dilution. Table S3. Overview over ELISA and Multiplex serology results. Table S4. Descriptive characteristics of obesity clinic cohort stratified by Helicobacter pylori infection status. Table S5. Descriptive characteristics of population-based reference cohort stratified by Helicobacter pylori infection status. Table S6. Descriptive characteristics of study population (excluding 71 subjects with non-European ethnicity) stratified by Helicobacter pylori infection status. Table S7. Descriptive characteristics of study population (excluding 71 subjects with non-European genetic ethnicity and 159 subjects with self-reported non-Danish ethnicity) stratified by Helicobacter pylori infection status. Table S8. Estimated odd ratios (OR) and standardized coefficient (beta) estimates with 95% confidence intervals (CI) for interactions between Helicobacter pylori seropositivity and female sex, body mass index standardized deviation score (BMI SDS), socioeconomic status (SES) 2–5 or post- pubertal puberty stage as indicators of hyperglycemia or fasting plasma glucose levels. Table S9. Estimated odd ratios (OR) with 95% confidence intervals (CI) for associations of different cut-off values for Helicobacter pylori seropositivity as an indicator of categorical (yes/no) cardiometabolic risk factors. Table S10. Standardized coefficient (beta) estimates with 95% confidence intervals (CI) for associations of different cut-off values for Helicobacter pylori seropositivity as an indicator of continuous cardiometabolic risk factors. Table S11. Estimated odd ratios (OR) with 95% confidence intervals (CI) for associations of Helicobacter pylori seropositivity as an indicator of categorical (yes/no) cardiometabolic risk factors, excluding 71 subjects with non-European genetic ethnicity. Table S12. Standardized coefficient (beta) estimates with 95% confidence intervals (CI) for associations of Helicobacter pylori seropositivity as an indicator of continuous cardiometabolic risk factors, excluding 71 subjects with non-European genetic ethnicity. Table S13. Estimated odd ratios (OR) with 95% confidence intervals (CI) for associations of Helicobacter pylori seropositivity as an indicator of categorical (yes/no) cardiometabolic risk factors, excluding 71 subjects with non-European genetic ethnicity and 159 subjects with self-reported non-Danish ethnicity. Table S14. Standardized coefficient (beta) estimates with 95% confidence intervals (CI) for associations of Helicobacter pylori seropositivity as an indicator of continuous cardiometabolic risk factors, excluding 71 subjects with non-European genetic ethnicity and 159 subjects with self-reported non-Danish ethnicity.