cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Life of Anne Moody: A Timeline (1940-2015)
Creators: name: Barnes, Roscoe
Publisher: name: figshare
Year: 2017
Subjects: subject: Ethnic Studies
subject: Gender studies
subject: History
subject: Literature
subject: 200104 Media Studies
subject: FOS: Media and communications
subject: Law
subject: FOS: Law
subject: Religious Studies

description: #AnneMoody This paper presents a timeline of the life history of civil rights pioneer Anne Moody, who wrote the classic, Coming of Age in Mississippi. She was born in 1940 near Centreville, Miss., and she died in 2015 in Gloster, Miss. Surprisingly, little is known about her life beyond the publication of her book in 1968. Her book chronicles her life as a poor black girl growing up under harsh conditions during segregation in Mississippi. In vivid and sometimes heartbreaking details, she gives a riveting account of her personal experiences at a time when black people could be lynched for speaking their minds. Her writing is raw and graphic. She gives a shocking and gritty look at Mississippi’s history. She writes of her struggle for civil rights and her prominent role in the movement. She also shares the stories of others who made sacrifices for freedom and justice. This paper provides key moments and important dates in Moody’s life history. It offers an overview of her life -- and events related to her story -- from 1940 to the present. The timeline will be updated periodically as new information becomes available.---------------------------------------------------------- Author’s Note: Questions about the Anne Moody History Project may be directed to Roscoe Barnes III via email at doctorbarnes3@gmail.com or roscoebarnes3@yahoo.com For updates on Anne Moody history and the on-going work of this community service project, please follow AMHP on Twitter (@AnneMoodyHP). Ideas and suggestions are also welcomed.
Alla ricerca di un modello territoriale agroecologico e integrato per l’agricoltura di montagna
Creators: name: Zollet, Simona
Publisher: name: Scienze del Territorio
Year: 2021

description: This paper summarizes some of the results of a research project conducted in the Belluno province on the topic of new farmers’ embeddedness in local agri-food systems. The article first outlines the agrarian development of the area over the past decades, describing the shortcomings of the dominant development model as well as its intrinsic tensions and beginning aspirations for change. Through interviews with new farmers and other territorial actors involved in the local agri-food system, the article aims at highlighting the potential for an agroecologically-oriented and territorially embedded transition of local agriculture, together with some of the emerging issues and leverage points for change.
description: Scienze del Territorio, Vol. 9 (2021): La nuova centralità della montagna / The new centrality of mountains
Agri-cultural resistance and local development
Creators: name: Bertolino, Maria Anna
Publisher: name: Scienze del Territorio
Year: 2021

description: The reconversion of raw lands into productive areas through cultivation may be considered as a practice of resistance toward territorial policies dictated from outside. So, marginal areas are taking new meaning in the eyes of their inhabitants or of the people who decide to settle here from the city. This attitude has triggered virtuous processes of development that are part of a general rethinking of mountains, in large part characterized by new creative ways of dealing with them, in terms of living and doing business in accordance to the local resources. In the following contribution will be analysed the recovery of two crops – lavender and rye – in the Susa Valley. They were studied in the research project MA.S.K.A. (Marginal Areas and Know-how in the Alps), funded by Compagnia di San Paolo Foundation and University of Turin in 2015 and 2016.
description: Scienze del Territorio, Vol. 9 (2021): La nuova centralità della montagna / The new centrality of mountains
Adult weight change and premenopausal breast cancer risk: A prospective pooled analysis of data from 628,463 women
Creators: name: Larsson, S.C
name: Bertrand, K.A
name: Jones, M.E
name: Connor, A.E
name: Ursin, G
name: Ozasa, K
name: Brook, M.N
name: Schoemaker, M.J
name: Baglietto, L
name: Swerdlow, A.J
name: Giles, G.G
name: Dossus, L
name: Key, T.J
name: Milne, R.L
name: O'Brien, K.M
name: Weiderpass, E
name: Sadakane, A
name: Sandler, D.P
name: Kitahara, C.M
name: Chen, Y
name: Adami, H.-O
name: Kaaks, R
name: Palmer, J.R
name: Visvanathan, K
name: Gram, I.T
name: Bernstein, L
name: Wright, L.B
name: Kirsh, V.A
name: Eliassen, A.H
name: Ma, H
name: Linet, M
name: Boutron-Ruault, M.-C
name: Wolk, A
name: Sund, M
name: Rohan, T.E
name: Trichopoulou, A
name: Willett, W.C
name: Hankinson, S.E
name: Riboli, E
name: Nichols, H.B
name: Tamimi, R.M
name: Sacerdote, C
name: Zeleniuch-Jacquotte, A
Publisher: name: Wiley-Liss Inc.
Year: 2020

description: Early-adulthood body size is strongly inversely associated with risk of premenopausal breast cancer. It is unclear whether subsequent changes in weight affect risk. We pooled individual-level data from 17 prospective studies to investigate the association of weight change with premenopausal breast cancer risk, considering strata of initial weight, timing of weight change, other breast cancer risk factors and breast cancer subtype. Hazard ratios (HR) and 95% confidence intervals (CI) were obtained using Cox regression. Among 628,463 women, 10,886 were diagnosed with breast cancer before menopause. Models adjusted for initial weight at ages 18–24 years and other breast cancer risk factors showed that weight gain from ages 18–24 to 35–44 or to 45–54 years was inversely associated with breast cancer overall (e.g., HR per 5 kg to ages 45–54: 0.96, 95% CI: 0.95–0.98) and with oestrogen-receptor(ER)-positive breast cancer (HR per 5 kg to ages 45–54: 0.96, 95% CI: 0.94–0.98). Weight gain from ages 25–34 was inversely associated with ER-positive breast cancer only and weight gain from ages 35–44 was not associated with risk. None of these weight gains were associated with ER-negative breast cancer. Weight loss was not consistently associated with overall or ER-specific risk after adjusting for initial weight. Weight increase from early-adulthood to ages 45–54 years is associated with a reduced premenopausal breast cancer risk independently of early-adulthood weight. Biological explanations are needed to account for these two separate factors.
title: saint Hilaire
Creators: name: Centre De Recherches Historiques / Anthropologie Historique Du Long Moyen Âge
Publisher: name: EHESS (School for Advanced Studies in Social Sciences)
Year: 2019

description: Évêque de Poitiers vers 350, il combattit l'arianisme, en expulsant les évêques et prêtres ariens ; mort en 367 ; auteur du traité de la trinité ; nommé père de l'Église par Pie IX ; attributs : un dragon ou un crapaud qu'il foule aux pieds.
Characterisation and transferability of transcriptomic microsatellite markers for Nothofagus species
Creators: name: V. El Mujtar
name: M. López
name: S. Amalfi
name: F. Pomponio
name: S. Marcucci Poltri
name: S. Torales
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Discriminant molecular markers are required for research on population genetics, as well as evolutionary studies involving identification of hybrids and parental species, or detection of the genome regions under selection. We provide a set of 27 transcriptomic microsatellite markers (SSRs) for South American Nothofagus species, derived from 73 Nothofagus alpina (=N. nervosa) annotated unigenes. Rates of cross-amplification ranged from 22% to 37%. Genetic characterisation of 22 transcriptomic SSRs for N. alpina and N. obliqua reveals low genetic variability, due to the general occurrence of one major allele at each locus, and high specificity, with few alleles shared between species (14%). At inter-species level 95% of loci were discriminant, with a total G''st over loci of 0.9, indicating that alleles were mostly fixed for all loci in both species. At intra-species level the number of markers with significant differentiation was 2.5 times higher for N. obliqua than for N. alpina populations. Moreover, transcriptomic SSRs showed higher performance compared with published anonymous microsatellites isolated from genome sequences without annotation. This set of transcriptomic microsatellites will be useful to the scientific community working on conservation and evolutionary aspects of Nothofagus species.
Reproduction, DNA methylation and biological age
Creators: name: Kresovich, J.K
name: Harmon, Q.E
name: Nichols, H.B
name: Sandler, D.P
name: Taylor, J.A
name: Xu, Z
Publisher: name: Oxford University Press
Year: 2019

description: STUDY QUESTION: Are reproductive characteristics associated with genome-wide DNA methylation and epigenetic age? SUMMARY ANSWER: Our data suggest that increasing parity is associated with differences in blood DNA methylation and small increases in epigenetic age. WHAT IS KNOWN ALREADY: A study of 397 young Filipino women (ages 20-22) observed increasing epigenetic age with an increasing number of pregnancies. STUDY DESIGN, SIZE, DURATION: We used data from 2356 non-Hispanic white women (ages 35-74) enrolled in the Sister Study cohort. PARTICIPANTS/MATERIALS, SETTING, METHODS: Data on reproductive history were ascertained via questionnaire. Of the 2356 women, 1897 (81%) reported at least one live birth. Among parous women, 487 (26%) women reported ever experiencing a pregnancy complication. Three epigenetic clocks (i.e. Hannum, Horvath and Levine) and genome-wide methylation were measured in DNA from whole blood using Illumina's HumanMethylation450 BeadChip. We estimated association β-values and 95% CIs using linear regression. MAIN RESULTS AND THE ROLE OF CHANCE: All three epigenetic clocks showed weak associations between number of births and epigenetic age (per live birth; Hannum: β = 0.16, 95% CI = 0.02, 0.29, P = 0.03; Horvath: β = 0.12, 95% CI =-0.04, 0.27, P = 0.14; Levine: β = 0.27, 95% CI = 0.08, 0.45, P = 0.01); however, additional adjustment for current BMI attenuated the associations. Among parous women, a history of abnormal glucose tolerance during pregnancy was associated with increased epigenetic age by the Hannum clock (β = 0.96; 95% CI = 0.10, 1.81; P = 0.03) and Levine clocks (β = 1.69; 95% CI = 0.54, 2.84; P < 0.01). In epigenome-wide analysis, increasing parity was associated with methylation differences at 17 CpG sites (Bonferroni corrected P≤ 1.0 × 10-7). LIMITATIONS, REASONS FOR CAUTION: We relied on retrospective recall to ascertain reproductive history and pregnancy complications. WIDER IMPLICATIONS OF THE FINDINGS: Our findings suggest that parity is associated with small increases in epigenetic age and with DNA methylation at multiple sites in the genome. STUDY FUNDING/COMPETING INTEREST(S): This research was supported by the Intramural Research program of the NIH, National Institute of Environmental Health Sciences (Z01-ES049033, Z01-ES049032 and Z01-ES044055). None of the authors have a conflict of interest. TRIAL REGISTRATION NUMBER: Not applicable.
Piccole scuole e territorio
Creators: name: Bartolini, Rudi
name: Mangione, Giuseppina Rita Jose
name: De Santis, Francesca
name: Tancredi, Anna
Publisher: name: Scienze del Territorio
Year: 2021

description: ‘Small schools’, characterized by a low number of pupils and located in ‘difficult’ territories, represent an important phenomenon of Italian school, especially as regards the first cycle of education. They are particularly frequent in mountain areas, small islands and in all those inland areas characterized by low population density, often presenting critical socio-economic situations and difficulties linked to isolation and distance from services. For these territories, they represent an important cultural protection and a wall against depopulation. Small schools often develop close ties with the relevant communities, playing an important role in the formation of place identity. From an educational and organizational point of view, the link with territories allows them to develop innovative solutions able to cope with difficulties. This article presents the results of a qualitative/quantitative survey carried out by INDIRE, Movimento delle Piccole scuole and ANCI pointed at investigating the existing forms of collaboration between small schools, municipalities and economic players in the area and identifying which conditions may favour an effective and sustainable functioning of small schools. A complex picture emerges, not always easy to interpret, where, in the light of evident critical issues, there are encouraging signs for the development of a fruitful dialogue among school, community and territory.
description: Scienze del Territorio, Vol. 9 (2021): La nuova centralità della montagna / The new centrality of mountains
Additional file 3 of Identification of a robust signature for clinical outcomes and immunotherapy response in gastric cancer: based on N6-methyladenosine related long noncoding RNAs
Creators: name: Han, Tenghui
name: Xu, Dong
name: Zhu, Jun
name: Li, Jipeng
name: Liu, Lei
name: Deng, Yanchun
Publisher: name: figshare
Year: 2021
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 3: Table S3. The twenty-three m6A-related prognostic lncRNAs.
Risalire
Creators: name: Pazzagli, Rossano
Publisher: name: Scienze del Territorio
Year: 2020

description: The mountains, primary components of Italian inland areas, has been hit by a drift whose main effects have been depopulation, emigration, social and productive rarefaction, land abandonment, hydrogeological vulnerability and landscape changes. The article recalls the historical dimension of this process and wonders what is left up there, in the large rural area, full of woods, pastures and villages. Not nothingness, nor emptiness, but a set of resources the central areas lack. The article is also an invitation to build a map of the best practices and of the return experiences, within a perspective of changing the economic, social and even cultural model.
description: Scienze del Territorio, Vol. 9 (2021): La nuova centralità della montagna / The new centrality of mountains
Regimen-specific rates of chemotherapy-related amenorrhea in breast cancer survivors
Creators: name: Gast, K.C
name: Stewart, E.A
name: Eshraghi, L
name: Nichols, H.B
name: Cathcart-Rake, E.J
name: Ruddy, K.J
name: Couch, F.J
name: Obidegwu, N
name: Vachon, C.M
name: Su, H.I
name: Rosenberg, S
name: Norman, A.D
Publisher: name: Oxford University Press
Year: 2019

description: Young women who have not begun or completed their desired childbearing at the time of diagnosis with breast cancer often wish to understand and minimize their risk of chemotherapy-related amenorrhea (CRA). However, the incidence of CRA after regimens that do not include either an anthracycline or a cyclophosphamide is poorly studied. For patients with human epidermal growth factor receptor 2-positive disease, anthracycline- and cyclophosphamide-sparing regimens (eg, carboplatin/taxane) are common (in combination with human epidermal growth factor receptor 2-directed therapy). In this study, accrued in collaboration with Army of Women, menstrual data were analyzed for 151 breast cancer survivors (median age = 41 years at diagnosis, and median time between last chemotherapy and survey = 62.5 months). Last menstrual period was before the last chemotherapy dose in 51% of the 86 participants who received anthracycline/cyclophosphamide/taxane, in 42% of the 43 who received only taxane/cyclophosphamide, and in 13% of the 15 who received carboplatin/taxane. This study suggests that carboplatin/taxane causes less CRA than cyclophosphamide-based regimens.
title: saint Maximin d'Aix
Creators: name: Centre De Recherches Historiques / Anthropologie Historique Du Long Moyen Âge
Publisher: name: EHESS (School for Advanced Studies in Social Sciences)
Year: 2019

description: Intendant de la famille de Béthanie, apôtre de la Provence, assimilé à un des 72 disciples du Christ ; associé à sainte Madeleine et saint Lazare ; évêque d'Aix.
Chi ha bisogno della montagna italiana?
Creators: name: Bergamasco, Giulia
name: Membretti, Andrea
name: Molinari, Maria
Publisher: name: Scienze del Territorio
Year: 2020

description: Due to urban and industrial development in the post-war period, the Italian Alps and Apennines have experience an intense phenomenon of depopulation, mainly caused by massive emigration to urban areas. Italian mountain regions, considered for a long time as marginal, neglected areas out of public and political attention, since long have also been affected by different forms of migration that question their representation as ‘places left behind’. At first focusing on the phenomenon of the ‘new mountain people’, and just later on taking into account also the role of foreign migrants in mountain areas, several studies highlighted the fundamental role im-migration flows in transforming Italian mountains, favouring a ‘return to the centre’ of highlands also – and above all – in public and political discourse. This article investigates, also through the analysis of Berceto case, the role – current and potential – of foreign immigrants in this re-thematization in economic, territorial as well as demographic and socio-cultural terms of the marginalized territories of the Alps and Apennines.
description: Scienze del Territorio, Vol. 9 (2021): La nuova centralità della montagna / The new centrality of mountains
Additional file 1 of Risk factors for mortality in patients over 70 years old with COVID-19 in Wuhan at the early break: retrospective case series
Creators: name: Zhu, Xu
name: Yuan, Wenzheng
name: Shao, Junwei
name: Huang, Kesheng
name: Wang, Qingbo
name: Yao, Shuang
name: Lu, Wei
name: Liu, Li
name: Fu, Tao
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Additional file 1. Clinical Classification of COVID-19 Patients.
La centralità della montagna in una inedita forma di urbanità
Creators: name: Decandia, Lidia
Publisher: name: Scienze del Territorio
Year: 2020

description: The article stems from an awareness of the fact that current models of organisation of the territory are undergoing great changes and that the interpretative categories we normally use for them no longer suffice to express the scope of transformations underway. It attempts to contradict the impression that the concept of urban must traditionally be associated with an idea of city as a centralised, delimited and circumscribed form. It does so, following in the footsteps of Scott and Soja, by proposing the embryos of a counter-history, illustrated by some significant moments, aimed at showing how the very idea of urban has created diverse spatial organisms along history, in which, notwithstanding the urban/rural dichotomy, even the mountains have sometimes taken on a role of great centrality. In observing the familiar connection between such land uses and the numerous contemporary signs showing us that a ‘new loving current’ appears to be binding the mountains to the cities, the article, drawing on the proposed genealogy, invites us to reappraise these territories no longer as external and peripheral but rather as an integral part of an extended, polyphonic city; the expression, therefore, of a new relationship of co-belonging between man and nature wherein – in the alternation of densification and gaps, slowness and speed, deserted spots and high-density nodes – even silences may finally be listened to, and the mountains acquire unprecedented centrality.
description: Scienze del Territorio, Vol. 9 (2021): La nuova centralità della montagna / The new centrality of mountains
Una finestra di opportunità per la montagna
Creators: name: Cattaneo, Maria Chiara
Publisher: name: Scienze del Territorio
Year: 2020

description: Centre and periphery, global and local as paradigms being uprooted in the pandemic that has swept all territories. If global trends confirm a tendency for the population to live in urban areas, the movements in the opposite direction regarding those who choose the mountain as the place to live could strengthen. The image of the Italian Alpine mountains today returns a complexity made of quality of life, personal safety, tourist attraction, quality of the environment, wealth of resources, to which spaces in proximity, quality of relationships, digitalization reducing distance and increasing mountain attractiveness are to be added. The more the paths aimed at redesigning the future will be participated and taking place in a productive relationship and dialogue with institutions and stakeholders, the more possibilities for a reinforced centrality of mountains will open up.
description: Scienze del Territorio, Vol. 9 (2021): La nuova centralità della montagna / The new centrality of mountains
Zweite Generation
Creators: name: Zloch, Stephanie
Publisher: name: Universität Osnabrück
Year: 2022
Subjects: subject: Zweite Integration
subject: Migration
subject: Integration
subject: Bildung
subject: Migrationsgesellschaft
subject: Bundesrepublik
subject: 300 - Sozialwissenschaften, Soziologie, Anthropologie
subject: 02.00 - Wissenschaft und Kultur allgemein: Allgemeines

description: Der bis heute aktuelle Begriff der ‚zweiten Generation‘ von Migrantinnen und Migranten entspringt weder einer rein pragmatischen Zählweise noch einer allseits anerkannten gesellschaftlichen Selbstbeschreibung. Die mit der ‚zweiten Generation‘ verbundenen Vorstellungen reichen vielmehr von der Annahme einer fortgeschrittenen ‚Integration‘ über Problemszenarien von Devianz und Prekariat bis hin zur Umdeutung des Begriffs für eine Selbstbehauptung von Migrantinnen und Migranten. Vor allem seit Ende des 20. Jahrhunderts entwickelten sich Alternativbegriffe, von denen allerdings keiner eine Alleinstellung in der Debatte um generationelle Dynamiken in der Migrationsgesellschaft erlangt hat. In diesem Beitrag wird im historischen Überblick die Verwendung unterschiedlicher Generationskonzepte identifiziert und diskutiert – von der frühesten Erwähnung einer second generation in den USA zu Beginn des 20. Jahrhunderts, über die Zwangsmigrationen am Ende des Zweiten Weltkriegs, die europäische Arbeitskräftemigration der 1950er bis 1980er Jahre, bis hin zum heutigen pluralen Migrations- und Fluchtgeschehen. Gesellschaftliche Beschreibungs- und Ordnungsversuche, die das Konzept Generation in Anspruch nehmen, wie ‚Millennials‘, ‚68er‘ oder ‚45er‘, erfreuen sich anhaltend hoher Beliebtheit. In Wirtschaft und Technik weist die Bezeichnung ‚zweite‘ oder ‚n-te Generation‘ ein Produkt als optimiert aus. Die geläufige Rede von einer ‚zweiten‘ oder auch ‚dritten Generation‘ von Migrantinnen und Migranten fügt sich allerdings nicht nahtlos in diese Reihung ein. Damit klingt bereits an, dass das Verständnis von Generationen mehrschichtig und zum Teil auch widersprüchlich sein kann. Dieser Beitrag erörtert daher, welche Implikationen, Bedeutungsverschiebungen und Effekte mit der konkreten Begriffsverwendung der ‚zweiten Generation‘ seit Beginn des 20. Jahrhunderts verbunden waren, wobei der Akzent auf der Migrationssituation in Deutschland liegt.
Yoga for Brain Fitness Issues
Creators: name: Hudson, Sally
Publisher: name: figshare
Year: 2017
Subjects: subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: Clinical Psychology
subject: Applied Psychology
subject: 170102 Developmental Psychology and Ageing
subject: 170203 Knowledge Representation and Machine Learning

description: Yoga for brain fitness- some preliminary studies. Yoga exercises involve deeper brain structures forming the limbic circuit and the right hemisphere. In this work we want to investigate the key areas of the brain during yoga exercises - how the brain works—how information exchange works.
Artifact -- Highly Automated Formal Proofs over Memory Usage of Assembly Code
Creators: name: Verbeek, Freek
name: Bockenek, Joshua
name: Binoy Ravindran
Publisher: name: Zenodo
Year: 2020
Subjects: Formal Verification
Assembly
x86-64

description: This is the artifact corresponding to the TACAS'20 submission entitled "Highly Automated Formal Proofs over Memory Usage of Assembly Code". This is the exact version as submitted an approved by the TACAS Artifact Evaluation committee.
Additional file 1 of Bacterioferritin: a key iron storage modulator that affects strain growth and butenyl-spinosyn biosynthesis in Saccharopolyspora pogona
Creators: name: Tang, Jianli
name: Zhu, Zirong
name: He, Haocheng
name: Liu, Zhudong
name: Xia, Ziyuan
name: Chen, Jianming
name: Hu, Jinjuan
name: Cao, Li
name: Rang, Jie
name: Shuai, Ling
name: Liu, Yang
name: Sun, Yunjun
name: Ding, Xuezhi
name: Hu, Shengbiao
name: Xia, Liqiu
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Hematology
subject: Plant Biology

description: Additional file 1: Table S1. Strains, plasmids and primers used in this study. Table S2. qRT-PCR primers used in this study. Table S3. Biological insecticidal activity of wt, Δbfr and ::bfr. Figure S1. LC-MS/MS identification of butenyl-spinosyn. Figure S2. Phylogenetic tree analysis of bacterioferritin. Figure S3. Construction and recombination schematic diagram of pKCcas9dO-sgRNA-UHA-DHA and pOJ260-kasOp*-bfr. Figure S4. Identification of Δbfr and ::bfr. Figure S5. Tricine-SDS-PAGE analysis and 1D-LC-MS/MS identification of heterologously expressed protein Bfr. Figure S6. Butenyl-spinosyn yield curve of the wild-type and mutants. Figure S7. Statistics of total protein and differential protein between the wild-type and mutant strains identified in the quantitative proteome. Figure S8. The expression fold change of bus family proteins between bfr mutant strains and wild-type strain. Figure S9. Verification of the transcription levels of iron homeostasis and oxidative stress-related proteins.
Progesterone, progesterone/estradiol and ART outcomes in day-5 transfer cycles
Creators: name: Ritika Arora
name: Chan, Crystal
name: Ye, Xiang Y.
name: Greenblatt, Ellen M.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: The objective of this study was to assess the effects of elevated luteal-phase progesterone levels (PE) and high progesterone/estradiol ratio (‘P/E2’ ratio) on IVF outcomes, exclusively in GnRH-antagonist cycles with day-5 embryo transfer. PE was not found to have a significant effect on implantation or clinical pregnancy rate (CPR) (OR 0.56, 95% CI 0.25–1.25, p = .16). Elevated ‘P/E2’ ratio (≥0.55) on trigger day was associated with a poorer response to stimulation and lower clinical pregnancy rates (OR 0.58, 95% CI 0.34–1.00, p = .05). Patients with PE and low ‘P/E2’ ratio yielded significantly more oocytes than patients with PE and high ‘P/E2’ ratio. The mean implantation rate per patient decreased by 60% in the group with PE and high ‘P/E2’ ratio in comparison to the group with PE and low ‘P/E2’ ratio (17.9%±36.6 vs. 45.5%±47.2, p = .06), although no statistical significance was observed. The detrimental effect of PE may be mitigated by culturing embryos to day-5 before embryo transfer. Combined assessment of serum progesterone and ‘P/E2’ ratio may predict pregnancy outcome better than progesterone levels alone.
Oficio Nro. SENESCYT-SGCT-SDIC-2018-0306-CO Registro de la red "Red de Investigación de Conocimiento, Software y Hardware Libre"
Creators: name: Senescyt
Publisher: name: Senescyt
Year: 2018

description: Oficio emitido por Senesct, ente rector del sistema de CTI, en el que se comunica la aprobación y registro con No. REG-RED-18-0009, de la Red de Investigación de Conocimiento, Software y Hardware Libre (RICHSL).
Hospitalization after Adolescent and Young Adult (AYA) Cancer: A population-based study in Utah
Creators: name: Trogdon, J.G
name: Kaddas, H.K
name: Kirchhoff, A.C
name: Ou, J.Y
name: Anderson, C
name: Ramsay, J.M
name: Nichols, H.B
Publisher: name: American Association for Cancer Research Inc.
Year: 2020

description: Background: Adolescents and young adults (AYA, age 15 39 years) with cancer may be at elevated risk for late morbidity following their cancer treatment, but few studies have quantified the excess burden of severe disease in this population. Using population-based data from Utah, we examined the risk of inpatient hospitalizations among AYA cancer survivors compared with their siblings and the general population. Methods: Survivors of AYA cancer who were 2 years from diagnosis and diagnosed from 1994 to 2015 (N 1/4 6,330), their siblings (N 1/4 12,924), and an age- and sex-matched comparison cohort (N 1/4 18,171) were identified using the Utah Population Database (UPDB). Hospitalizations from 1996 to 2017 were identified from statewide discharge records in the UPDB. We estimated multivariable-adjusted hazard ratios (HR) for first hospitalization and rate ratios (RR) for total hospitalizations for survivors relative to the matched comparison cohort and siblings. Results: Overall, the risk of a first hospitalization was higher among AYA cancer survivors than the matched populationbased cohort [HR 1/4 1.93; 95% confidence interval (CI), 1.81 2.06]. Risk was most elevated for survivors of leukemia (HR 1/4 4.76), central nervous system tumors (HR 1/4 3.45), colorectal cancers (HR 1/4 2.83), non-Hodgkin lymphoma (HR 1/4 2.76), and breast cancer (HR 1/4 2.37). The rate of total hospitalizations was also increased among survivors relative to the comparison cohort (RR 1/4 2.05; 95% CI, 1.95 2.14). Patterns were generally similar in analyses comparing survivors to their siblings. Conclusions: AYA cancer survivors have a higher burden of inpatient hospitalization than their siblings and the general population. Impact: Results indicate the importance of long-term, riskbased follow-up care to prevent and treat severe morbidities after cancer treatment.
Genome-wide association study of anti-Müllerian hormone levels in pre-menopausal women of late reproductive age and relationship with genetic determinants of reproductive lifespan
Creators: name: Taylor, J.A
name: Zeleniuch-Jacquotte, A
name: Schoemaker, M.J
name: Eliassen, A.H
name: Nichols, H.B
name: Sandler, D.P
name: Swerdlow, A.J
name: Murray, A
name: Soares, A.L.G
name: Jones, M.E
name: Borges, M.-C
name: Kraft, P
name: Lawlor, D.A
name: Ruth, K.S
name: Hankinson, S.E
Publisher: name: Oxford University Press
Year: 2019

description: Anti-Müllerian hormone (AMH) is required for sexual differentiation in the fetus, and in adult females AMH is produced by growing ovarian follicles. Consequently, AMH levels are correlated with ovarian reserve, declining towards menopause when the oocyte pool is exhausted. A previous genome-wide association study identified three genetic variants in and around the AMH gene that explained 25% of variation in AMH levels in adolescent males but did not identify any genetic associations reaching genome-wide significance in adolescent females. To explore the role of genetic variation in determining AMH levels in women of late reproductive age, we carried out a genome-wide meta-analysis in 3344 pre-menopausal women from five cohorts (median age 44-48 years at blood draw). A single genetic variant, rs16991615, previously associated with age at menopause, reached genome-wide significance at P = 3.48 × 10-10, with a per allele difference in age-adjusted inverse normal AMH of 0.26 standard deviations (SD) (95% confidence interval (CI) [0.18,0.34]). We investigated whether genetic determinants of female reproductive lifespan were more generally associated with pre-menopausal AMH levels. Genetically-predicted age at menarche had no robust association but genetically-predicted age at menopause was associated with lower AMH levels by 0.18 SD (95% CI [0.14,0.21]) in age-adjusted inverse normal AMH per one-year earlier age at menopause. Our findings provide genetic support for the well-established use of AMH as a marker of ovarian reserve.
title: saint Blaise
Creators: name: Centre De Recherches Historiques / Anthropologie Historique Du Long Moyen Âge
Publisher: name: EHESS (School for Advanced Studies in Social Sciences)
Year: 2019

description: Saint thaumaturge et guérisseur, évêque de Sébaste ; devenu ermite il est martyrisé sous Dioclétien ; coiffé d'une mitre, il a pour attribut un peigne de fer, deux cierges entrecroisés ou un cierge en torsade ; souvent associé à saint Érasme et saint Gilles
Mindfulness-Meditation-Reference-Books.pdf
Creators: name: Hudson, Sally
Publisher: name: figshare
Year: 2017
Subjects: subject: Clinical Psychology
subject: Applied Psychology
subject: Neuroscience and Physiological Psychology
subject: 170205 Neurocognitive Patterns and Neural Networks
subject: FOS: Psychology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: 15 Top Mindfulness Meditation Reference Books
Risk versus Benefit of Chemoprevention among Raloxifene and Tamoxifen Users with a Family History of Breast Cancer
Creators: name: Nichols, H.B
name: Anderson, C
name: Sandler, D.P
name: House, M
Publisher: name: American Association for Cancer Research Inc.
Year: 2019

description: Tamoxifen and raloxifene have been approved for the primary prevention of breast cancer in high-risk women, but are associated with an increased risk of serious side effects. Few studies have characterized risk–benefit profiles for chemoprevention among women who initiate tamoxifen or raloxifene outside of a clinical trial setting. Use of raloxifene and tamoxifen for chemoprevention was self-reported in 2014 to 2016 by participants in The Sister Study, a prospective cohort of women with a sister who had been diagnosed with breast cancer. After exclusions, 432 current raloxifene users and 96 current tamoxifen users were matched to 4,307 and 953 nonusers, respectively, on age and year of cohort enrollment. Conditional logistic regression was used to evaluate characteristics associated with chemoprevention use. Risk–benefit profiles were examined using published indices that assess the level of evidence (none, moderate, strong) that the benefits of chemoprevention outweigh the risk of serious side effects. Among current chemoprevention users, 44% of tamoxifen users and 5% of raloxifene users had no evidence of a net benefit. In analyses of factors associated with chemoprevention use, having strong evidence of benefit was a significant predictor of raloxifene use, but not of tamoxifen use. In our sample of women with a first-degree family history of breast cancer, raloxifene was more commonly used for breast cancer prevention than tamoxifen. Most raloxifene users, but <60% of tamoxifen users, were likely to benefit. Use of risk–benefit tables can help women and their healthcare providers make an informed decision about breast cancer chemoprevention.
With The Scion of Ikṣvāku
Creators: name: RODRIGUES, TENSING CARLOS
Publisher: name: figshare
Year: 2017
Subjects: subject: History
subject: Anthropology
subject: FOS: Sociology
subject: Archaeology
subject: Geography
subject: Sociology

description: By and large, like Mahābhārat, Rāmāyaṇa too is preponderantly populated with the kshatriya, besides the vaḍukar. One seldom comes across any brāmhaṇa other than the above referred holy men and women who seem to have taken to the forests in search of quietude and peace. These look totally different from the Kuru-Pañcāla brāhman pushing their way across the Indo-Gangetic plain. To use the language of Śatapatha Brāmhaṇa, the hermits Rāma meets in Deccan seem to have “forgotten their dharma of sacrifice enjoined in the sacred texts and adopted a new dharma against sacrifice”. (Chakravarti, 1974 : Jaina Literature in Tamil, 4)
Ideal Gas Dark Matter Model
Creators: name: Neupane, Bishal
Publisher: name: Zenodo
Year: 2025

description: This thesis mathematically explores the concept of dark matter as an ideal gas and its potential to explain the flat rotation curves observed in galaxies. It proposes that the pressure exerted by ideal gas dark matter halos can play a significant role in galactic dynamics.The thesis develops a model based on hydrostatic equilibrium and the ideal gas law, assuming spherical symmetry and isothermality for the dark matter halo. It derives the relevant equations and numerically solves them for the isothermal sphere case, implementing a Python-based solver.The numerical results demonstrate that the isothermal ideal gas dark matter halo model can indeed produce rotation curves that exhibit the characteristic flatness seen in galaxies at larger radii. This finding suggests that the pressure of an ideal gas dark matter component could contribute to the dynamics of galaxies and offer a partial explanation for the dark matter phenomenon. However, the thesis also critically discusses the limitations of the simplified isothermal sphere model, including its infinite mass and the idealized assumptions made. It concludes by outlining potential refinements and extensions for future research, such as exploring non-isothermal models, truncated halos, self-interacting dark matter, and more sophisticated dynamical simulations to further assess the viability of the ideal gas dark matter hypothesis. Ultimately, this work provides a theoretical investigation into an alternative dark matter model, highlighting the potential importance of pressure in understanding galaxy structure and rotation.
Additional file 6 of Chrysoeriol suppresses hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes and inhibits JAK2/STAT3 signaling
Creators: name: Wu, Jia-Ying
name: Chen, Ying-Jie
name: Fu, Xiu-Qiong
name: Li, Jun-Kui
name: Chou, Ji-Yao
name: Yin, Cheng-Le
name: Bai, Jing-Xuan
name: Wu, Ying
name: Wang, Xiao-Qi
name: Li, Amy Sze-man
name: Wong, Lut Yi
name: Yu, Zhi-Ling
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Additional file 6. Original blot images of immunoblotting results in Additional file 2. Representative images of STAT3, phospho-STAT3(Tyr705) and β-actin are shown. Bands are shown on different films because of different exposure time.
GUAVA JUICE REDUCES CHOLESTEROL LEVEL FOR ELDERLY WITH HYPERTENSION
Creators: name: Efendi, Ferry
Publisher: name: figshare
Year: 2017
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences

description: Introduction: Hypertensive disease is closely related to high cholesterol level, which may act as one of causes of death in elderly. The objective of this study was to analyze the effect of guava juice on the reduction of cholesterol level of hypertensive elderly at Community Health Center, Pacar Keling, Surabaya. Method: Quasy–experimental was used in this study. Sample comprised of 14 respondents who met the inclusion criteria. The independent variable was guava juice and the dependent variable was cholesterol level. Data were collected using questionnaire and observation. Data were analyzed by Paired t–Test and Independent t–Test with signi fi cance level of α < 0.05. Result: The result showed that guava juice gave a significant effect to cholesterol level of elderly with hypertension (p = 0.000). Discussion: It can be concluded that guava juice can reduce cholesterol level in elderly with hypertension. The reduction of cholesterol level may result from vitamin C, pectin, and potassium contained in guava juice, which have effect on cholesterol regulation in the body. Guava juice can be provided as daily diet for elderly. Further studies are suggested to investigate other variables, such as diet consumed, age, activity, and obesity.
Enabling change through education for vulnerable and disadvantaged children and their families, through the perspectives of early childhood professionals, children and families
Creators: name: WENDY PATRICIA ROBERTS
Publisher: name: Monash University
Year: 2017
Subjects: subject: 130102 Early Childhood Education (excl. Maori)
subject: FOS: Educational sciences

description: Social inclusion, access, participation and engagement, are key to social and learning success in early childhood. Supporting engagement by children and families experiencing vulnerability and disadvantaged can transform lives. This study explores the perspectives of Early Childhood Educators and Professionals (ECEPs) and the families they support. Building respectful, empathetic, collaborative relationships that support educational engagement by children and their families experiencing vulnerability and disadvantage is crucial as effective family engagement is the key to early years learning success.
Adult physical activity and breast cancer risk in women with a family history of breast cancer
Creators: name: Nichols, H.B
name: Niehoff, N.M
name: White, A.J
name: Zhao, S
name: Sandler, D.P
Publisher: name: American Association for Cancer Research Inc.
Year: 2019

description: Background: Recreational physical activity has been consistently associated with reduced breast cancer risk. Less is known about how family history of breast cancer affects the association and whether it varies by menopausal status. Methods: The Sister Study is a cohort of 50,884 women who had a sister with breast cancer but no prior breast cancer themselves at enrollment. Women reported all recreational sport/exercise activities they participated in over the past 12 months. Hours/week and MET-hours/week of physical activity were considered in association with breast cancer risk. Hazard ratios (HR) and 95% confidence intervals (CI) were calculated with Cox regression. Extent of family history, examined as a modifier, was characterized by a Bayesian score incorporating characteristics of the family structure. Results: During follow-up (average 8.4 years), 3,023 cases were diagnosed. Higher hours/week (HR ≥7vs<1 = 0.77; 95% CI, 0.66–0.90) and MET-hours/week (HR quartile4vs1 = 0.75; 95% CI, 0.67–0.85) of physical activity were associated with reduced postmenopausal breast cancer risk. Hours/week and MET-hours/week were associated with suggestively increased premenopausal breast cancer risk (MET-hours/week HR quartile4vs1 = 1.25; 95% CI, 0.98–1.60). Associations did not vary with extent of family history. However, the increased risk in premenopausal women may be limited to those with stronger family history. Conclusions: In women with a family history of breast cancer, physical activity was associated with reduced postmenopausal, but not premenopausal, breast cancer risk and was not modified by extent of family history. Impact: This was the first study to examine the association between physical activity and breast cancer risk in a large population with a family history of breast cancer.
Muquiá- a criação que veio do nada - inglês.pdf
Creators: name: Cássio Almeida
Publisher: name: figshare
Year: 2017
Subjects: Uncategorized

description: This article was accomplished through studies in the field of philosophy and articles of introduction to modern physics, quantum physics, string theory, etc. The main philosophers studied were Martin Heiddegger and Gottfried Leibniz, especially their assumptions about the order of the universe as providence. The question of nothing arises as an inquiry of the origins that to be answered needs to take into account the ontological character of the questioning being. Hence lies a methodological problem that pure scientific inquiry is unable to solve. Where science, however can not offer a satisfactory answer, philosophy responds.
Lebenswelten im Rheinischen Revier : Beiträge zum nachhaltigen Strukturwandel
Creators: name: Förster, Agnes
name: Sánchez-Molero Martínez, José Miguel
name: Strobel, Eva Christine
name: RWTH Aachen. Lehrstuhl Für Planungstheorie Und Stadtentwicklung
name: REVIERa-Transformationsplattform Der RWTH
Publisher: name: RWTH Aachen University
Year: 2022

description: Aachen : RWTH Aachen University (2022). doi:10.18154/RWTH-2021-11767
description: Published by RWTH Aachen University, Aachen
title: apôtres-12
Creators: name: Centre De Recherches Historiques / Anthropologie Historique Du Long Moyen Âge
Publisher: name: EHESS (School for Advanced Studies in Social Sciences)
Year: 2019

description: Désigne le groupe de douze apôtres au complet (Cène, Ascension, Pentecôte, Jugement dernier...) ; on ne précise pas si le groupe est figuré avant ou après le remplacement de Judas
miR-20b-5p functions as tumor suppressor microRNA by targeting cyclinD1 in colon cancer
Creators: name: Yang, Hui
name: Lin, Jian
name: Jiang, Jinling
name: Ji, Jun
name: Wang, Chao
name: Zhang, Jun
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: MicroRNA functions as an oncogenic regulator or tumor suppressor in various human tumors. Although bioinformatics analysis suggested that miRNA-20b-5p may be associated with the tumorigenesis, its role in colon cancer remains elusive. To investigate the role of miRNA-20b-5p, HCT116 cell, a human colon cancer cell line used in therapeutic research and drug screenings, was chosen as a model system for our in vitro studies. We first carried out bioinformatics and microarray analysis. To gain further mechanism insight, flow cytometry was performed to determine cell apoptosis and cell cycle, and western blot or immunohistochemistry were employed to check the expression of CCND1/CDK/FOXM1 axis in HCT116 cells. In addition, wound-healing migration assay and transwell assay were conducted to uncover the effect of miR-20b-5p on tumor migration and invasion. Finally, we examined the role of miR-20b-5p by subcutaneous xenograft mouse models. Our data have shown that miRNA-20b-5p inhibited the cell cycle, migration, and invasion in HCT116 cells, but had no effect on cell apoptosis. CyclinD1 (CCND1) was identified as a direct target of miR-20b-5p. Overexpression of miRNA-20b-5p downregulated CCND1 level in HCT-116 cells. Mechanically, the inhibition of cell cycle, migration, and invasion of CC cells mediated by miRNA-20b-5p are through regulating the CCND1/CDK4/FOXM1 axis. Furthermore, miRNA-20b-5p inhibited the tumorigenesis in Balb/c nude mice CC xenograft models. Our data demonstrated that miR-20b-5p may serve as a tumor suppressor in colon cancer by negatively regulating CCND1, implying that miR-20b-5p could be a potential therapeutic target for the treatment of colon cancer.