cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2 of Predictive value of insulin resistance surrogates for the development of diabetes in individuals with baseline normoglycemia: findings from two independent cohort studies in China and Japan
Creators: name: Shangguan, Qing
name: Liu, Qiuling
name: Yang, Ruijuan
name: Zhang, Shuhua
name: Sheng, Guotai
name: Kuang, Maobin
name: Zou, Yang
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 2: Figure S1. The cumulative hazard of prediabetes among the TyG index quartiles. TyG index: the triglyceride-glucose index. Figure S2. The cumulative hazard of prediabetes among the TyG-BMI quartiles. TyG-BMI: triglyceride glucose-body mass index. Figure S3. The cumulative hazard of prediabetes among the TG/HDL-C ratio quartiles. TG/HDL-C ratio: triglyceride/high-density lipoprotein cholesterol ratio. Figure S4. The cumulative hazard of prediabetes among the MetS-IR quartiles. MetS-IR: metabolic score for insulin resistance.
Application of a Two-Level Targeter for Low-Thrust Spacecraft Trajectories
Creators: name: York, Collin E.
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Aerospace engineering not elsewhere classified

description: Applications of electric propulsion to spaceflight in multi-body environments require a targeting algorithm to produce suitable trajectories on the ground and on board spacecraft. The two-level targeter with low thrust (TLT-LT) provides a framework to implement differential corrections in computationally-limited autonomous spacecraft applications as well as the larger design space of pre-mission planning. Extending existing two-level corrections algorithms, applications of the TLT-LT to spacecraft with a range of propulsive capabilities, from nearly-impulsive to low-thrust, are explored. The process of determining partial derivatives is generalized, allowing reduced logical complexity and increased flexibility in designing sequences of thrusting and ballistic segments. Various implementation strategies are explored to enforce constraints on time and other design variables as well as to improve convergence behavior through the use of dynamical systems theory and attenuation factors. The TLT-LT is applied to both nearly-impulsive and low-thrust spacecraft applications in the circular restricted three-body problem to demonstrate the flexibility of the framework to correct trajectories across the spectrum of thrust magnitude. Finally, parameter continuation is employed to extend a family of trajectories from a solution with nearly-impulsive thrust events to the low-thrust regime, and the characteristics of this transition are investigated.
TV_BESSJF 2024 cruise,Thalassa R/V
Creators: name: Benoit, LOUBRIEU
name: Javier, ESCARTIN
Publisher: name: Sismer
Year: 2024

description: Initiative « Valorisation bathymétrique des transits de la flotte océanographique » L'acquisition de données bathymétriques sur ce transit est à l'initiative d'un groupe de géologues et géophysiciens, en concertation avec la Flotte Océanographique Française. L'objectif global de cette initiative est de généraliser l'acquisition de données de sondeurs multifaisceaux sur les transits des navires de la flotte, en vue de a) compléter les couvertures bathymétriques existantes à moyenne et haute résolution et contribuer à la cartographie bathymétrique globale des océans, b) établir un protocole d'acquisition et traitement des données des transits valorisées, et c) faciliter les travaux de recherche à travers le partage publique des données acquises lors de ces transits. Les données sont destinées à un usage de cartographie moyenne résolution (modèle numérique de terrain au pas de grille d'une centaine de mètres). L'acquisition de données se fait dans un mode contraint : la vitesse du navire est celle fixée par le transit, sans ajustement vis-à-vis de la qualité des données ou leur résolution; le sondeur multifaisceaux est placé dans un mode automatique. L'acquisition n'est pas nécessairement suivie en continu par un opérateur spécialisé; les profils de célérité utilisés pour l'acquisition des données et le calcul des sondes sont établis à partir de tables globales, sans mesure in-situ de température et salinité lors de l'acquisition (de type sondes de température).Les données sont pré-traitées et validées et sont destinées à être mise à disposition à court terme dans la base de données des navires océanographiques Sismer. L'acquisition est limitée aux eaux internationales, pour lesquelles aucune demande d'autorisation n'est nécessaire. Cette initiative se fait également en interaction avec le projet Seabed2030.
Additional file 3 of Predictive value of insulin resistance surrogates for the development of diabetes in individuals with baseline normoglycemia: findings from two independent cohort studies in China and Japan
Creators: name: Shangguan, Qing
name: Liu, Qiuling
name: Yang, Ruijuan
name: Zhang, Shuhua
name: Sheng, Guotai
name: Kuang, Maobin
name: Zou, Yang
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 3: STROBE_checklist_(S1 text).
Status, Inheritance Pattern and Mechanism of Field-Evolved Resistance to Gel Bait Insecticides in The German Cockroach
Creators: name: Zain, Ashari
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Genetics not elsewhere classified

description: German cockroach (Blattella germanica L.) is an important urban pest that poses health risks. They carry pathogenic microorganisms, and the allergens present in their feces and cast skins can trigger asthma attacks. Gel bait formulations containing insecticides (indoxacarb and fipronil) have been used for German cockroach control for more than a decade. However, historical data suggests that cockroaches can develop resistance to insecticides that are repeatedly used. Therefore, we investigated the status and inheritance patterns of fipronil and indoxacarb resistance in cockroach strains collected from the state of Indiana and Illinois. In the first objective, topical dose-response bioassays were performed to determine fipronil and indoxacarb resistance levels in adult males of three field strains (D-IL, I-IN, and S-IN) and the laboratory-susceptible Orlando strain. Comparison of LD50 (median lethal dose) values between the susceptible and field strains revealed that resistance to both insecticides in the D-IL and I-IN strains was <10-fold. However, fipronil and indoxacarb resistance levels in the S-IN strain were 20- and >10,000-fold, respectively. In the second objective, choice feeding bioassays were performed to test the performance of the resistant S-IN strain (adult males) on commercial fipronil and indoxacarb baits. Complete (100%) mortality of the S-IN strain was observed on fipronil baits. However, average mortality on indoxacarb baits was ~20% at 14d. In the third objective, synergist bioassays were done with PBO and DEF to investigate the mechanism of indoxacarb resistance. PBO did not significantly increase mortality in the S-IN strain at LD50, but DEF did, suggesting increased hydrolase activity as a potential mechanism of indoxacarb resistance. In the last objective, reciprocal crosses were performed between the resistant S-IN strain and the susceptible Orlando strain to determine patterns of insecticide resistance. Topical bioassays and associated LD50 values for the F1 generation adult males indicated that fipronil resistance was inherited as an incompletely dominant trait with sex-linkage. In contrast, indoxacarb resistance was inherited as a codominant trait and was not sex-linked. Our results indicate that resistance can evolve independently in different field strains. High-level indoxacarb resistance observed in the S-IN strain warrants additional research on the indoxacarb target-site as a possible resistance mechanism.
PATIENT ACTIVATION AND MEDICATION ADHERENCE AMONG MEDICARE BENEFICIARIES WITH TYPE 2 DIABETES
Creators: name: Zheng, Dandan
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Pharmaceutical sciences

description: The objectives of this study were to assess patient activation levels, to assess association between sociodemographic characteristics and patient activation, to assess association between health status characteristics and patient activation, and to assess association between patient activation and medication adherence among Medicare beneficiaries with type 2 diabetes. A retrospective cohort study was conducted using data from the 2009 through 2013 Medicare Current Beneficiary Survey (MCBS). Patient activation was measured with the Patient Activation Supplement in the MCBS and was categorized as low, moderate, and high levels based on activation scores. Medication adherence was assessed with proportion of days covered (PDC) using Medicare Part D administrative records from the MCBS within a period of six months after measurement of patient activation. The sample included Medicare beneficiaries who completed the MCBS Patient Activation questionnaire, who were diagnosed with type 2 diabetes, and who were 18 or older. Beneficiaries were excluded if they responded “Not ascertained,” “Not Applicable,” “Don’t know” or “Refused” to more than 50 percent of the Patient Activation questions, did not have continuous Medicare Part A and Part D coverage throughout the assessment period, had less than two Medicare Part D claims for an antidiabetic medication throughout the assessment period, used insulin during the assessment period, resided in long-term care facilities, or had Alzheimer’s disease, dementia, mental retardation or mental disorder. All analyses were conducted in SAS 9.4 for Unix environment. An a priori alpha level of 0.05 was used to determine significance. Bivariate and multivariable weighted ordinal logistic regression were applied for assessing associations. A total of 571 individuals met sample selection criteria. The mean age was 72.4 years. Of the 571 persons in the sample, 27.5 percent were at low activation level, 38.7 percent were at moderate activation level, and 33.7 percent were at high activation level. Approximately three-fourths of the sample persons were adherent to antidiabetic medications. Low activation was more likely to be found in males, less educated patients, and patients without arrhythmia. Ex-smokers as compared to non-smokers and overweight patients as compared to those with healthy weight were less likely to report low activation. In multivariable logistic analysis adjusting for race, gender, osteoporosis, Charlson Comorbidity Index score, and number of prescribed medications, patient activation level was not significantly associated with medication adherence. Non-Whites and patients with a Charlson Comorbidity Index score of 1 as compared to those with a score of 0 were more likely to be non-adherent. A lower number of prescribed medications was associated with higher odds of non-adherence.
Latinx Literatures and Cultures in the U.S. and Beyond
Creators: name: Challener, Scott
Publisher: name: unknown
Year: 2020
Subjects: subject: Hispanic Americans
subject: American literature
subject: Twentieth century
subject: Hispanic Americans--Social life and customs
subject: Latin Americans--Study and teaching
subject: Hispanic Americans--Study and teaching
subject: Culture--Study and teaching

description: This course is a study of Latinx literatures and cultures produced in the twentieth and twenty-first centuries. We will concentrate our attention on works by Chicanos, Mexican Americans, Puerto Ricans, Cuban Americans, and Dominican Americans. We will consider how these works represent and participate in the upheavals that characterize the period—from economic crisis, revolution, decolonization, and mass migration, to political and social mobilization, state repression, neoliberalization, border conflict, and the transformation of mass media. We will examine specific literary and cultural objects—novels, poems, plays, films, music—and their reception histories. We will investigate the cultural work these objects and their authors perform. How do they project, embrace, and constitute the meanings of Latinx literature and culture? How do they contravene, suppress, or refuse certain fantasies of the "Latin"? We will address questions about race and racialization, gender and sexuality, and assimilation and transculturation, as well as about the politics of Spanglish and Spanish and the situation of Latinx artists in the global marketplace. We will conclude by looking at several works by Latin American artists that consider these questions from "beyond" the United States—that is, from outside of the political borders of the U.S., and from the margins of the canon and the culture industry.
Latinx Literatures and Cultures in the U.S. and Beyond
Creators: name: Challener, Scott
Publisher: name: Humanities Commons
Year: 2020
Subjects: subject: Hispanic Americans
subject: Hispanic Americans--Social life and customs
subject: Culture--Study and teaching
subject: Hispanic Americans--Study and teaching
subject: Latin Americans--Study and teaching
subject: American literature
subject: Twentieth century

description: This course is a study of Latinx literatures and cultures produced in the twentieth and twenty-first centuries. We will concentrate our attention on works by Chicanos, Mexican Americans, Puerto Ricans, Cuban Americans, and Dominican Americans. We will consider how these works represent and participate in the upheavals that characterize the period—from economic crisis, revolution, decolonization, and mass migration, to political and social mobilization, state repression, neoliberalization, border conflict, and the transformation of mass media. We will examine specific literary and cultural objects—novels, poems, plays, films, music—and their reception histories. We will investigate the cultural work these objects and their authors perform. How do they project, embrace, and constitute the meanings of Latinx literature and culture? How do they contravene, suppress, or refuse certain fantasies of the “Latin”? We will address questions about race and racialization, gender and sexuality, and assimilation and transculturation, as well as about the politics of Spanglish and Spanish and the situation of Latinx artists in the global marketplace. We will conclude by looking at several works by Latin American artists that consider these questions from “beyond” the United States—that is, from outside of the political borders of the U.S., and from the margins of the canon and the culture industry.
sj-pdf-1-prq-10.1177_10659129211027658 – Supplemental material for Technology Threats to Employment, Issues, and Candidate and Party Preferences in the United States
Creators: name: Heinrich, Tobias
name: Witko, Christopher
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-pdf-1-prq-10.1177_10659129211027658 for Technology Threats to Employment, Issues, and Candidate and Party Preferences in the United States by Tobias Heinrich and Christopher Witko in Political Research Quarterly
Additional file 1 of Enhanced in vivo blood brain barrier transcytosis of macromolecular cargo using an engineered pH-sensitive mouse transferrin receptor binding nanobody
Creators: name: Esparza, Thomas J.
name: Su, Shiran
name: Francescutti, Caroline M.
name: Rodionova, Elvira
name: Kim, Joong Hee
name: Brody, David L.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Additional file 1. Supplemental information, including supplemental methods, supplemental results and figures, supplemental tables, supplemental discussion, and supplemental references.
Mumps epidemiology in Germany 2007-11
Creators: name: Takla, Anja
name: Wichmann, Ole
name: Klinc, Christina
name: Hautmann, H.
name: Rieck, Thorsten
name: Koch, Judith
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2013
Subjects: subject: Humans
subject: Female
subject: Male
subject: Adolescent
subject: Adult
subject: Germany/epidemiology
subject: Middle Aged
subject: Young Adult
subject: Age Distribution
subject: Vaccination/statistics & numerical data
subject: Incidence
subject: Child
subject: Disease Outbreaks
subject: Health Surveys
subject: Immunization/statistics & numerical data
subject: Mandatory Reporting
subject: Mumps/diagnosis
subject: Mumps/epidemiology
subject: Mumps/prevention & control
subject: Orchitis/complications
subject: Orchitis/epidemiology
subject: 610 Medizin

description: In Germany, mumps has been notifiable until 2013 only in the five Eastern federal states (EFS) of former East Germany. Due to different immunisation policies until 1990 and varying vaccination coverages thereafter, mumps incidences cannot be extrapolated to the 11 Western federal states (WFS). We studied mumps-related International Classification of Diseases (ICD-10) code diagnoses claimed through statutory health insurances between 2007 and 2011 to estimate countrywide mumps incidences in the outpatient sector, and compared them with case numbers from ambulatory notification data. Overall, 32,330 outpatient mumps cases were claimed. Annual incidence ranged between 9.3/100,000 and 11.8/100,000 and showed a significant decreasing trend. Compared with EFS, mumps incidence in WFS was higher and indicated a shift towards older age groups. Notified outpatient case numbers in EFS were 13-fold lower and from voluntary surveillance during an outbreak in the WFS Bavaria 8-fold lower than from insurance data (n=316 versus n=4,217 and n=238 versus 1,995, respectively). Of all notified cases with available information, 75.4% (EFS) and 57.6% (Bavaria) were unvaccinated; 6.8% (EFS) and 19.3% (Bavaria) required hospitalisation. In Germany, mumps is still endemic despite decades of vaccination, with considerable underreporting in the established notification systems.
Diagnosis of West Nile Virus Human Infections: Overview and Proposal of Diagnostic Protocols Considering the Results of External Quality Assessment Studies
Creators: name: Sambri, Vittorio
name: Capobianchi, Maria R.
name: Cavrini, Francesca
name: Charrel, Rémi
name: Mantke, Oliver Donoso
name: Escadafal, Camille
name: Franco, Leticia
name: Gaibani, Paolo
name: Gould, Ernest A.
name: Niedrig, Matthias
name: Papa, Anna
name: Pierro, Anna
name: Rossini, Giada
name: Sanchini, Andrea
name: Tenorio, Antonio
name: Varani, Stefania
name: Vázquez, Ana
name: Vocale, Caterina
name: Zeller, Hervé
Publisher: name: Robert Koch-Institut
Year: 2013
Subjects: subject: West Nile virus
subject: state of the art laboratory diagnostic
subject: external quality assurance
subject: 610 Medizin

description: West Nile virus, genus Flavivirus, is transmitted between birds and occasionally other animals by ornithophilic mosquitoes. This virus also infects humans causing asymptomatic infections in about 85% of cases and
Additional file 1 of A non-linear connection between the total cholesterol to high-density lipoprotein cholesterol ratio and stroke risk: a retrospective cohort study from the China Health and Retirement Longitudinal Study
Creators: name: Xiao, Binhui
name: Cao, Changchun
name: Han, Yong
name: Yang, Fangju
name: Hu, Haofei
name: Luo, Jiao
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Mathematical Sciences not elsewhere classified
subject: Mental Health

description: Additional file 1: Table S1. Relationship between TC/HDL-C ratio and the stroke composite endpoint in different models with competing risk of mortality. Table S2. Relationship between TC/HDL-C ratio and the incident stroke in different models. Table S3. Relationship between TC/HDL-C ratio and the incident stroke in different models after excluding participants with missing values for BMI, physical activity, and Cystatin C.
POTENTIAL UTILIZATION OF U.S. HARDWOODS FOR PRODUCTION OF CLARINETS
Creators: name: Zhao, Yue
Publisher: name: Purdue University Graduate School
Year: 2019

description: Clarinets are perfect example of musical instruments produced from tropical wood species Grenadilla (Dalbergia melanoxylon), wood species which could have a suspicion origin. It is of high interest for producers and consumers to find a sustainable substitution for the currently used material for its production. Therefore, a case study was developed in cooperation with local clarinet producer to evaluate possible substitution of Grenadilla for a new material sourced from U.S. temperate forests. Specifically, a study was conducted on the production of clarinets from four U.S. hardwood species, Hard Maple, Black Walnut, Black Cherry and Yellow Poplar. These instruments were compared with clarinets made of Grenadilla and ABS (Acrylonitrile butadiene styrene) plastic, materials currently used for clarinet production. To improve workability (machining), wood treatment with cactus juice (Methyl Methacrylate) was also investigated. Clarinets made from U.S. hardwood species and their treatment were benchmarked with traditionally made clarinets from Grenadilla and ABS plastic. Producer and users perception surveys were conducted. Seventeen experienced clarinet testers and ten experienced players evaluated eleven different instruments. All study participants were very open to the idea of using U.S. hardwoods for production of clarinets. Instruments made of U.S. hardwoods were evaluated and graded from four perspectives: appearance & color, touch & feel, tone & sound, and overall quality. Quantitative and qualitative measures were used to assess the feasibility of proposed material substitution. Study findings are supported by statistical analysis. Based on the Tukey results, clarinet made of treated Maple was comparable with both Grenadilla and ABS plastic clarinets. Mann-Whitney results show that treated Maple was also a best substitution option in all categories when compared with ABS plastic, but when compared with Grenadilla, treated Maple was comparable only in touch/feel and tone/sound aspects. Cactus juice treatment improved material properties, especially workability, which is a very important property for the production of clarinets. In conclusion, treated Hard Maple was the most promising substitution material.
Abnahme der Spermaqualität bei gesunden Männern aus ungewollt kinderlosen Partnerschaften
Creators: name: Thierfelder, Wulf
name: Seher, C.
name: Dortschy, Reinhard
name: Engel, S.
Publisher: name: Robert Koch-Institut
Year: 1999
Subjects: subject: Spermaqualität
subject: ungewollte Kinderlosigkeit
subject: 610 Medizin

description: In einer retrospektiven Studie wurden Untersuchungs- und Spermiogrammbefunde von 3821 Männern erhoben. Die Daten stammen aus dem Einzugsbereich der Andrologischen Abteilung der Universitätsklinik Leipzig. Es sollte untersucht werden, ob bei Patienten ohne anamnestische oder klinische Befunde eine Verschlechterung der Spermaqualität innerhalb der Untersuchungsjahre 1985 bis 1996 eingetreten ist. Weiterhin sollten Aussagen über eine mögliche Abhängigkeit der Spermiogrammbefunde vom Geburtsjahr gewonnen werden. Innerhalb der Gruppe der 25–34jährigen (n=1650) haben sich von 1985 bis 1996 die absolute Spermienzahl von 195 Mio auf 138 Mio, die Spermienkonzentration von 79,7 auf 52,6 Mio/ml und der Anteil morphologisch normaler Spermien von 64,6% auf 59,6% signifikant (p
description: In a retrospective study examination- and spermiogram-data were collected from 3821 men. The data came from the vicinity of the andrological department of the Leipzig university-clinic. It should be examined, whether first-examined patients without anamnestic or abnormal clinical findings did show a deterioration of the sperm-quality within the examination-years 1985 to 1996. Furtheron information should be collected concerning a possible dependence of the spermiogram data from the year of birth. Within the group of the 25 to 34 year old men (n=1650) in the time frame from 1985 until 1996 the absolute sperm count of 195 millions changed to 138 millions, the sperm concentration of 79,7 was reduced to 52,6 Mio/ml and the fraction of morphological normal sperm was diminished from 64,6% to 59,6% (all results with p
sj-pdf-1-pms-10.1177_00315125211029240 - Supplemental material for A Portuguese Adaptation of the Teruel Orthorexia Scale and a Test of Its Utility with Brazilian Young Adults
Creators: name: Roberto da Silva, Wanderson
name: Cruz Marmol, Carlos Hernani
name: Nogueira Neves, Angela
name: Marôco, João
name: Bonini Campos, Juliana Alvares Duarte
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-1-pms-10.1177_00315125211029240 for A Portuguese Adaptation of the Teruel Orthorexia Scale and a Test of Its Utility with Brazilian Young Adults by Wanderson Roberto da Silva, Carlos Hernani Cruz Marmol, Angela Nogueira Neves, João Marôco and Juliana Alvares Duarte Bonini Campos in Perceptual and Motor Skills
Biological and Phylogenetic Characteristics of Yellow Fever Virus Lineages from West Africa
Creators: name: Stock, Nina K.
name: Laraway, Hewád
name: Faye, Ousmane
name: Diallo, Mawlouth
name: Niedrig, Matthias
name: Sall, Amadou A.
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2012
Subjects: subject: Animals
subject: Humans
subject: Amino Acid Sequence
subject: Molecular Sequence Data
subject: Genotype
subject: Phylogeny
subject: Base Sequence
subject: Genome Viral
subject: Liver/virology
subject: Viral Proteins/genetics
subject: Cell Line
subject: Aedes/virology
subject: Africa Western
subject: Genetic Variation
subject: Hep G2 Cells
subject: Insect Vectors/virology
subject: RNA Viral/genetics
subject: Sequence Analysis RNA
subject: Viral Proteins/chemistry
subject: Yellow Fever/genetics
subject: Yellow Fever/virology
subject: Yellow fever virus/classification
subject: Yellow fever virus/genetics
subject: Yellow fever virus/isolation & purification
subject: 610 Medizin

description: The yellow fever virus (YFV), the first proven human-pathogenic virus, although isolated in 1927, is still a major public health problem, especially in West Africa where it causes outbreaks every year. Nevertheless, little is known about its genetic diversity and evolutionary dynamics, mainly due to a limited number of genomic sequences from wild virus isolates. In this study, we analyzed the phylogenetic relationships of 24 full-length genomes from YFV strains isolated between 1973 and 2005 in a sylvatic context of West Africa, including 14 isolates that had previously not been sequenced. By this, we confirmed genetic variability within one genotype by the identification of various YF lineages circulating in West Africa. Further analyses of the biological properties of these lineages revealed differential growth behavior in human liver and insect cells, correlating with the source of isolation and suggesting host adaptation. For one lineage, repeatedly isolated in a context of vertical transmission, specific characteristics in the growth behavior and unique mutations of the viral genome were observed and deserve further investigation to gain insight into mechanisms involved in YFV emergence and maintenance in nature.
THE IMPACTS OF ROAD CONSTRUCTION WORK ZONES ON THE TRANSPORTATION SYSTEM, TRAVEL BEHAVIOR OF ROAD USERS AND SURROUNDING BUSINESSES.
Creators: name: Agyemang, Augustine M.
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Civil engineering not elsewhere classified

description: In our daily use of the transportation system, we are faced with several road construction work zones. These construction work zones change how road users interact with the transportation system due to the changes that occur in the system such as increased travel times, increased delay times and vehicle stopped times. A microscopic traffic simulation was developed to depict the changes that occur in the transportation system. The impacts of the changes in the transportation system on the human travel behavior was investigated using ordered probit and logit models using five independent variables; age, gender, driving experience, annual mileage and percentage of non-work trips. Finally, a business impact assessment framework was developed to assess the impact of the road construction work zones on various businesses categories such as grocery stores, pharmacy, liquor stores and fast foods. Traffic simulation results showed that the introduction of work zones in the road network introduces an increase in delay times, vehicle stopped times, and travel times. Also, the change in average travel times, delay times and vehicle stopped times differed from road link to link. The observed average changes saw an increase as high as 318 seconds per vehicle, 237 seconds per vehicle and 242 seconds per vehicle for travel time, delay time and vehicle stopped time, respectively, for the morning peak period. An average increase as high as 1607 seconds per vehicle, 258 seconds per vehicle and 265 seconds per vehicle was observed for travel time, delay time and vehicle stopped time, respectively, for the afternoon peak period. The statistical model results indicated that, on a work trip, a high driving experience, high annual mileage, and high percentage of non-work trips makes an individual more likely to change their route. The results also showed gender difference in route choice behavior. Concerning business impacts, businesses in the work zone were impacted differently with grocery and pharmacy stores having the highest and lowest total loss in revenue, respectively.
Rauchen und Lungenkrebs bei Frauen: Werden die Männer überholt?
Creators: name: Junge, B.
Publisher: name: Robert Koch-Institut
Year: 1998
Subjects: subject: 610 Medizin

description: Wenn Frauen rauchen wie Männer, sterben sie wie Männer. Die Gültigkeit dieser eingängigen Feststellung wurde anhand der Entwicklung von Raucheranteilen und Lungenkrebs-Sterbeziffern überprüft. Während sich die Sterblichkeit an Lungenkrebs bei Nichtrauchern kaum zwischen beiden Geschlechtern unterscheidet, sind in der Gesamtbevölkerung die Sterbeziffern der Männer erheblich höher als die der Frauen. Die zeitliche Entwicklung führt allerdings aufgrund sinkender männlicher und steigender weiblicher Sterbeziffern dazu, daß sich beide einander nähern. Bei den Raucheranteilen ist ein ähnlicher Trend zu beobachten: Die in der Vergangenheit deutlich höheren Werte der Männer haben sich durch beachtliche Rückgänge den eher gestiegenen Anteilen der Frauen angenähert. In Deutschland finden sich bereits bei Jugendlichen in einzelnen Untergruppen für Mädchen höhere Raucheranteile als für Jungen, in Schweden ist schon in der Gesamtbevölkerung der Raucheranteil bei Frauen höher als bei Männern. Daß das Rauchen mit dem Auftreten von Lungenkrebs zusammenhängt, ist durch unzählige epidemiologische Studien und in Tierversuchen belegt worden. Nun wurde kürzlich auch noch der Nachweis auf molekularer Ebene erbracht: Das im Tabakrauch enthaltene Benzo(a)pyren schädigt das Gen p53, ein für die Krebsabwehr zuständiges Gen, welches bei rund 60% der Lungenkrebsfälle defekt ist [1]. Die MAK-Kommission der Deutschen Forschungsgemeinschaft hat in ihrer neuesten Liste gesundheitsschädlicher Arbeitsstoffe das Passivrauchen, also das unfreiwillige Einatmen von Tabakrauch, in die oberste Kategorie krebserzeugender Arbeitsstoffe eingeordnet [2]; dies hatte einige Jahre zuvor bereits die amerikanische Umweltschutzbehörde EPA getan [3]. Die Zahl der jährlich dem Rauchen zuschreibbaren Todesfälle liegt in Deutschland bei über 100 000 [4]. Trotz dieser überzeugenden Fakten sind in Deutschland 36% der Männer und 21% der Frauen im Alter von 15 Jahren und darüber Raucher [5]. Wie sich das Rauchen und seine bekannteste Folge, der Lungenkrebs, im Verhältnis der Geschlechter darstellt, soll im folgenden anhand von Zahlen aus den letzten Jahrzehnten betrachtet werden.
American Literature's Hemispheric Address: 1823-1923 (Fall 2019)
Creators: name: Challener, Scott
Publisher: name: unknown
Year: 2019
Subjects: subject: Americans--Social life and customs
subject: Nineteenth century
subject: Twentieth century
subject: American literature

description: This course is a study of American literature's address to and engagement with the hemisphere in the long nineteenth century. As such, it is first and foremost an inquiry into the concepts—"America," "literature," "address," "hemisphere," race and period—that animate our study. Our first task, then, is to turn these concepts into problems. What constitutes American literature in this period? What are the conditions of its production, circulation, and reception? To what, and to whom, is it addressed? Who are its readers, its publics, its characters, its addressees? Who are its legitimators, authorities, and apologists? The course is arranged around major transformations in hemispheric relations, including the invocation and exercise of the Monroe Doctrine (1823), the annexation of Texas, the U.S. Mexican War (1846-1848), the Treaty of Guadeloupe (1848), U.S. expansionism before and after the Spanish American War (1898), the construction and administration of the Panama Canal Zone (1903-1914), and the Mexican Revolution (1910-1920). We conclude with a look at the hemispheric contexts of the Harlem Renaissance.
Texture Synthesis and Photorealistic Re-rendering of Room Scene Images
Creators: name: Ziga, Kyle J.
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Electrical engineering not elsewhere classified

description: In this thesis, we investigate methods for texture synthesis and texture re-rendering of indoor room scene images. The goal is to create a photorealistic redesign of interior spaces by replacing surface finishes with a new product based on a single room scene image. Speci cally, we focus on automating this process to reduce manual input while enabling high-quality and easy-to-use experience. The most common method of rendering textures into a scene is called texture mapping. Texture mapping involves mapping pixels in a texture sample to vertices in an object model. Typically, a large texture sample is required to perform texture mapping properly. Given a small texture sample, texture synthesis creates a large sized texture that appears to havebeen made by the same underlying process. In the first part of this thesis, we present a method of texture synthesis that automatically determines a set of parameters to produce satisfactory results based on the texture types. The next challenge is to create a photorealistic re-rendering of the synthesized texture in the room scene image. 3D scene information such as geometry, lighting and reflectance is crucial to making the re-rendered image realistic. These properties contribute to the image formation process and must be estimated to create a scene-consistent modi cation. Knowing these parameters allows effects like highlights, shadows and inter-object reflections to be maintained during the re-rendering process. We detail methods for estimatingthese parameters from a single indoor image. Finally, we will show a web-based implementation of these methods using the WebGL library ThreeJS.
American Literature's Hemispheric Address: 1823-1923 (Fall 2019)
Creators: name: Challener, Scott
Publisher: name: Humanities Commons
Year: 2019
Subjects: subject: American literature
subject: Americans--Social life and customs
subject: Nineteenth century
subject: Twentieth century

description: This course is a study of American literature’s address to and engagement with the hemisphere in the long nineteenth century. As such, it is first and foremost an inquiry into the concepts—“America,” “literature,” “address,” “hemisphere,” race and period—that animate our study. Our first task, then, is to turn these concepts into problems. What constitutes American literature in this period? What are the conditions of its production, circulation, and reception? To what, and to whom, is it addressed? Who are its readers, its publics, its characters, its addressees? Who are its legitimators, authorities, and apologists? The course is arranged around major transformations in hemispheric relations, including the invocation and exercise of the Monroe Doctrine (1823), the annexation of Texas, the U.S. Mexican War (1846-1848), the Treaty of Guadeloupe (1848), U.S. expansionism before and after the Spanish American War (1898), the construction and administration of the Panama Canal Zone (1903-1914), and the Mexican Revolution (1910-1920). We conclude with a look at the hemispheric contexts of the Harlem Renaissance.
State of Knowledge and Data Gaps of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Humans
Creators: name: MERS-CoV, Research Group WHO
name: Buchholz, Udo
name: Kühne, Anna
name: Blümel, Benjamin
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2013
Subjects: subject: 610 Medizin

description: Background: Between September 2012 and 22 October 2013, 144 laboratory-confirmed and 17 probable MERS-CoV cases from nine countries were notified to WHO. Methods: We summarize what is known about the epidemiology, virology, phylogeny and emergence of MERS-CoV to inform public health policies. Results: The median age of patients (n=161) was 50 years (range 14 months to 94 years), 64.5% were male and 63.4% experienced severe respiratory disease. 76.0% of patients were reported to have ≥1 underlying medical condition and fatal cases, compared to recovered or asymptomatic cases were more likely to have an underlying condition (86.8% vs. 42.4%, p
ОЦЕНКА РИСКА РАЗВИТИЯ ОСЛОЖНЕНИЙ ЦИРРОЗА ПЕЧЕНИ РАЗЛИЧНОЙ ЭТИОЛОГИИ ПРИ ИСПОЛЬЗОВАНИИ УЛЬТРАЗВУКОВОЙ ЭЛАСТОГРАФИИ ПЕЧЕНИ
Creators: name: Юсупалиева, Г.А.
name: Махкамова, Н.Х.
name: Кутумов, Х.Ю.
Publisher: name: Zenodo
Year: 2025

description: Цирроз печени является одной из ведущих причин смертности в мире, сопровождаясь высокой инвалидизацией и ухудшением качества жизни пациентов. Важнейшей проблемой при циррозе печени различных этиологий является предсказание и своевременная диагностика осложнений, таких как портальная гипертензия, печеночная недостаточность, асцит, кровотечения из варикозно расширенных вен и другие. Это требует применения высокоточных, неинвазивных методов диагностики, способных обеспечить точную оценку состояния печени и степени её фиброза.
sj-pdf-1-wso-10.1177_17474930211027834 - Supplemental material for Stroke in India: A systematic review of the incidence, prevalence, and case fatality
Creators: name: Jones, Stephanie P
name: Baqai, Kamran
name: Clegg, Andrew
name: Georgiou, Rachel
name: Cath, Harris
name: Holland, Emma-Joy
name: Kalkonde, Yogeshwar
name: Lightbody, Catherine E
name: Maulik, Pallab BK
name: Srivastava, Padma MV
name: Durai, Pandian J
name: Kulsum, Patel
name: Sylaja, PN
name: Watkins, Caroline L
name: Maree L, Hackett
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-wso-10.1177_17474930211027834 for Stroke in India: A systematic review of the incidence, prevalence, and case fatality by Stephanie P Jones, Kamran Baqai, Andrew Clegg, Rachel Georgiou, Harris Cath, Emma-Joy Holland, Yogeshwar Kalkonde, Catherine E Lightbody, Pallab BK Maulik, Padma MV Srivastava, Pandian J Durai, Patel Kulsum, PN Sylaja, Caroline L Watkins, Hackett Maree L and on behalf of the NIHR Global Health Research Group on IMPROVIng Stroke carE in India (IMPROVISE) Collaboration in International Journal of Stroke
Study of Inclusion Removal in a Gas-stirred Ladle
Creators: name: Liu, Wenjie
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified

description: Steel refining via ladle treatment is critical to final product quality in the steel manufacturing process. The process of ladle refining serves to assist in the removal of non-metallic inclusions, which can impact steel product fatigue strength, impact toughness, and corrosion resistance. While the steelmaking industry has in place best practices for the process, it remains costly to performing trial and error testing on the ladle. In addition, an understanding of the flow phenomena within the ladle during operation can provide industry with key knowledge necessary to improve the efficiency and throughput of the process. The method by which this research aims to address this is through the development of a comprehensive computational fluid dynamics (CFD) model of the steelmaking ladle. Such a model, capable of predicting the inclusion removal process and flow patterns within the ladle, would serve to provide the necessary information to advance steelmaking efficiency and improve product quality. A full scale unsteady state three dimensional CFD model has been developed to predict removal of inclusion during gas-stirring in a ladle. The Eulerian-Eulerian model was used to simulate the multiphase flow, the Population Balanced Model (PBM) has been used to describe the inclusion distribution. The phenomena of bottom-blow argon bubble coalescence and breakup were considered. Additionally, a model has been developed to predict inclusion removal during operation. For the inclusion removal model, the CFD-PBM coupled method has been proposed to investigate the inclusion behavior. This includes representing phenomena such as inclusion-bubble collision, inclusion removal by attachment to the ladle refractory, and inclusion capture by slag floating on the surface of the melt. The unified computational model for simulation of fluid flow and inclusion removal was validated against industry measurements provided by Nucor Steel. Using this CFD model and a ladle geometry and set of baseline conditions provided by Nucor Steel, studies were carried out to examine flow development, gas bubble distribution, and inclusion removal. Examining the impacts of inclusion size on removal rate indicated that larger inclusions are removed faster. This agreed with both industry expectations and data found in published literature. In addition, the model predicts that bubble-inclusion collision are primarily responsible for 99% inclusion removal in a gas-stirred ladle.
sj-pdf-1-wso-10.1177_17474930211026519 - Supplemental material for Risk factors for delayed-onset dementia after stroke or transient ischemic attack—A five-year longitudinal cohort study
Creators: name: Ismail, Moamina
name: Mok, Vincent CT
name: Wong, Adrian
name: Au, Lisa
name: Yiu, Brian
name: Wang, Zhaolu
name: Chu, Winnie CW
name: Chan, Anne YY
name: Fan, Florence SY
name: Ma, Sze H
name: Ip, Vincent
name: Ip, Bonaventure
name: Ma, Karen
name: Leung, Howan
name: Soo, Yannie OY
name: Leung, Thomas WH
name: Ko, Ho
name: Lau, Alexander YL
name: Lam, Bonnie YK
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-wso-10.1177_17474930211026519 for Risk factors for delayed-onset dementia after stroke or transient ischemic attack—A five-year longitudinal cohort study by Moamina Ismail, Vincent CT Mok, Adrian Wong, Lisa Au, Brian Yiu, Zhaolu Wang, Winnie CW Chu, Anne YY Chan, Florence SY Fan, Sze H Ma, Vincent Ip, Bonaventure Ip, Karen Ma, Howan Leung, Yannie OY Soo, Thomas WH Leung, Ho Ko, Alexander YL Lau and Bonnie YK Lam in International Journal of Stroke
Towards further reduction and replacement of animal bioassays in prion research by cell and protein misfolding cyclic amplification assays
Creators: name: Boerner, Susann
name: Wagenführ, Katja
name: Daus, Martin L.
name: Thomzig, Achim
name: Beekes, Michael
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2013
Subjects: subject: Animals
subject: Humans
subject: Cattle
subject: Sensitivity and Specificity
subject: Creutzfeldt-Jakob Syndrome/metabolism
subject: Encephalopathy Bovine Spongiform/metabolism
subject: PrPSc Proteins/chemistry
subject: PrPSc Proteins/genetics
subject: Biological Assay/instrumentation
subject: Biological Assay/methods
subject: Blotting Western
subject: Cattle Diseases/metabolism
subject: Cricetinae
subject: Disinfection/methods
subject: Electrophoresis Polyacrylamide Gel
subject: Neuroglia/metabolism
subject: Neuroglia/pathology
subject: PrPC Proteins/chemistry
subject: PrPC Proteins/genetics
subject: PrPC Proteins/metabolism
subject: PrPSc Proteins/metabolism
subject: Prion Diseases/genetics
subject: Prion Diseases/metabolism
subject: Protein Engineering/instrumentation
subject: Protein Engineering/methods
subject: Protein Folding
subject: Scrapie/metabolism
subject: Sheep/metabolism
subject: 610 Medizin

description: Laboratory animals have long since been used extensively in bioassays for prions in order to quantify, usually in terms of median infective doses [ID50], how infectious these pathogens are in vivo. The identification of aberrant prion protein as the main component and self-replicating principle of prions has given rise to alternative approaches for prion titration. Such approaches often use protein misfolding cyclic amplification (PMCA) for the cell-free biochemical measurement of prion-associated seeding activity, or cell assays for the titration of in vitro infectivity. However, median seeding and cell culture infective doses (SD50 and CCID50, respectively) of prions are neither formally congruent nor definitely representative for ID50 titres in animals and can be therefore only tentatively translated into the latter. This may potentially impede the acceptance and use of alternative methods to animal bioassays in prion research. Thus, we suggest performing PMCA and cell assays jointly, and to check whether these profoundly different test principles deliver consistent results in order to strengthen the reliability and credibility of prion ID50 assessments by in vitro methods. With regard to this rationale, we describe three pairs of PMCA and glial cell assays for different hamster-adapted prion agents (the frequently used 263K scrapie strain, and 22A-H scrapie and BSE-H). In addition, we report on the adaptation of quantitative PMCA to human variant Creutzfeldt-Jakob disease (vCJD) prions on steel wires for prion disinfection studies. Our rationale and methodology can be systematically extended to other types of prions and used to further reduce or replace prion bioassays in rodents.