cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Estimation of source parameters using a non-Gaussian probability density function in a Bayesian framework
Creators: name: Yoshimitsu, Nana
name: Maeda, Takuto
name: Sei, Tomonari
Publisher: name: figshare
Year: 2024
Subjects: subject: Statistics
subject: FOS: Mathematics

description: Additional file 1: Figure S1. Estimates of seismic parameters calculate from synthetic spectral ratios, assuming (a) an F-distribution and (b) a normal distribution. Top panels indicate the result of seismic moment, middle panels indicate the result of $${f}_{c1}$$ f c 1 , and the bottom panels indicate the result of $${f}_{c2}$$ f c 2 . Figure S2. Sampling distribution of project onto a 2D plane with irregular spectral shape. (a), (b), and (c) represent the sampling distributions obtained from the event in Fig. 8(a). (d), (e), and (f) are obtained from the event in Fig. 8(b). (g), (h), and (i) are obtained from the event in Fig. 8(c). (a), (d), and (g) indicate the relationships between moment ratio and $${f}_{c1}$$ f c 1 . (b), (e), and (h) indicate the relationships between $${f}_{c1}$$ f c 1 and $${f}_{c2}$$ f c 2 . (c), (f), and (i) indicate the relationship between moment ratio and $${f}_{c2}$$ f c 2 . Figure S3. Stress drops within an earthquake cluster after event selection. Red circles indicate the results obtained from large earthquakes, and blue triangles indicate results obtained from smaller earthquakes. Dark color obtained from the source model proposed by Brune (1970) and light color obtained from the source model proposed by Madariaga (1976).
Textbook for SPAN 341: Hispanic Culture Through Literature: Polemics and Debates (1100-1600)
Creators: name: Wacks, David
Publisher: name: unknown
Year: 2017
Subjects: subject: Latin American literature
subject: Textbooks
subject: Middle Ages
subject: Sixteenth century
subject: Seventeenth century
subject: Spanish literature
subject: Eighteenth century
subject: Literature--Study and teaching
subject: Latin Americans--Social life and customs
subject: Teaching

description: Syllabus and Course Reader (Creative Commons Licensed) of survey course of premodern Hispanic literature and culture taught as a series of debates on social questions (see https://davidwacks.uoregon.edu/2017/12/14/survey4/)

Course description: This class introduces students to a variety of texts written in Spain and the New World from 1100-1600 through discussions of current day social and political issues. The course is organized in a series of polemics (debates) on key issues raised by literary texts. Students will prepare both sides of the debate based on literary evidence, stage debates, and write on the socio-political significance of the issues and their representation.
Cancer Tissue Engineering: development of new 3D models and technologies to support cancer research
Creators: name: CAVO, MARTA MARIA
Publisher: name: Universit� degli studi di Genova
Year: 2018

description: The activity of research of this thesis focuses on the relevance that appropriate models reproducing the in vivo tumor microenvironment are essential for improving cancer biology knowledge and for testing new anticancer compounds. Animal models are proven not to be entirely compatible with the human system, and the success rates between animal and human studies are still unsatisfactory. On the other hand, 2D cell cultures fail to reproduce some aspects of tumor system. These limitations have a significant weight especially during the screening of novel antitumor drugs, as it was demonstrated that cells are less sensitive to treatments when in contact with their microenvironment. To obtain the same tumor cell inhibition levels observed in vivo, the culture environment has to reflect the 3D natural environment. Natural or synthetic hydrogels
reported successful outcomes in mimicking ECM environment.
During this PhD, I developed different gel-based scaffolds to be use as substrates for the culture of breast cancer cells. In detail, I developed different gels for low and highly aggressive cancer cell lines (i.e. MCF-7 and MDA-MB-231), obtaining significant results as regards the reproduction of key features normally present into the in vivo environment.
Considering the importance of the metastasis process in breast cancer evolution, I then focused on a new set-up for the observation of cancer cell motility and invasion. In particular, I combined a bioreactor-based bioengineering approach with single cell analysis of Circulating Tumor Cells (CTCs). This part of work was carried out at the Dipartiment of Biomedicine of the University of Basel (CH) that, among its equipment, has a cell celector machine for single cell analysis.
At the end of this work, I provided a proof-of-concept that the approach can work, as well as evidence that the cells can be extracted from the device and used for molecular analysis.
Structural and immunochemical relatedness suggests a conserved pathogenicity motif for secondary cell wall polysaccharides in Bacillus anthracis and infection-associated Bacillus cereus
Creators: name: Kamal, Nazia
name: Ganguly, Jhuma
name: Saile, Elke
name: Klee, Silke
name: Hoffmaster, Alex
name: Carlson, Russell W.
name: Forsberg, Lennart S.
name: Kannenberg, Elmar L.
name: Quinn, Conrad P.
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2017
Subjects: subject: 610 Medizin

description: Bacillus anthracis (Ba) and human infection-associated Bacillus cereus (Bc) strains Bc G9241 and Bc 03BB87 have secondary cell wall polysaccharides (SCWPs) comprising an aminoglycosyl trisaccharide repeat: →4)-β-d-ManpNAc-(1→4)-β-d-GlcpNAc-(1→6)-α-d-GlcpNAc-(1→, substituted at GlcNAc residues with both α- and β-Galp. In Bc G9241 and Bc 03BB87, an additional α-Galp is attached to O-3 of ManNAc. Using NMR spectroscopy, mass spectrometry and immunochemical methods, we compared these structures to SCWPs from Bc biovar anthracis strains isolated from great apes displaying “anthrax-like” symptoms in Cameroon (Bc CA) and Côte d’Ivoire (Bc CI). The SCWPs of Bc CA/CI contained the identical HexNAc trisaccharide backbone and Gal modifications found in Ba, together with the α-Gal-(1→3) substitution observed previously at ManNAc residues only in Bc G9241/03BB87. Interestingly, the great ape derived strains displayed a unique α-Gal-(1→3)-α-Gal-(1→3) disaccharide substitution at some ManNAc residues, a modification not found in any previously examined Ba or Bc strain. Immuno-analysis with specific polyclonal anti-Ba SCWP antiserum demonstrated a reactivity hierarchy: high reactivity with SCWPs from Ba 7702 and Ba Sterne 34F2, and Bc G9241 and Bc 03BB87; intermediate reactivity with SCWPs from Bc CI/CA; and low reactivity with the SCWPs from structurally distinct Ba CDC684 (a unique strain producing an SCWP lacking all Gal substitutions) and non-infection-associated Bc ATCC10987 and Bc 14579 SCWPs. Ba-specific monoclonal antibody EAII-6G6-2-3 demonstrated a 10–20 fold reduced reactivity to Bc G9241 and Bc 03BB87 SCWPs compared to Ba 7702/34F2, and low/undetectable reactivity to SCWPs from Bc CI, Bc CA, Ba CDC684, and non-infection-associated Bc strains. Our data indicate that the HexNAc motif is conserved among infection-associated Ba and Bc isolates (regardless of human or great ape origin), and that the number, positions and structures of Gal substitutions confer unique antigenic properties. The conservation of this structural motif could open a new diagnostic route in detection of pathogenic Bc strains.
Limited susceptibility of rhesus macaques to a cowpox virus isolated from a lethal outbreak among New World monkeys
Creators: name: Mätz-Rensing, Kerstin
name: Yue, Constanze
name: Klenner, Jeanette
name: Ellerbrok, Heinz
name: Stahl-Hennig, Christiane
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2017
Subjects: subject: 610 Medizin

description: This study was undertaken to investigate the susceptibility of rhesus monkeys to the calpox virus, an orthopoxvirus (OPXV) of the Cowpox virus species (CPXV), which is uniformly lethal in common marmosets. Six rhesus monkeys were either intravenously (i.v.) or intranasally (i.n.) exposed to the virus. Monitoring of the macaques after viral exposure included physical examinations, the determination of viral load by real-time PCR and plaque assay, and the analysis of humoral responses. Two i.v. inoculated animals developed numerous classical pox lesions that started after inoculation at days 7 and 10. Both animals became viremic and seroconverted. They exhibited maximal numbers of lesions of approximately 50 and 140 by day 21. One animal completely recovered, while the other one suffered from a phlegmonous inflammation of a leg initially induced by a secondarily infected pox lesion and was euthanized for animal welfare reasons. In contrast to previous pathogenicity studies with the calpox virus in marmosets, none of the four animals inoculated intranasally with doses of the calpox virus exceeding those used in marmosets by orders of magnitude showed typical clinical symptoms. No viral DNA was detectable in the blood of those animals, but three animals seroconverted. In two of these three animals, infectious virus was sporadically isolated from saliva. This indicates that rhesus monkeys are less susceptible to calpox virus infection, which limits their use in further intervention studies with OPXV.
Additional file 6 of Intrauterine growth pattern in Butajira HDSS, Southern Ethiopia: BUNMAP pregnancy cohort
Creators: name: Mengistu, Yalemwork G.
name: Hailemariam, Damen
name: Roro, Meselech A.
name: Endris, Bilal S.
name: Tesfamariam, Kokeb
name: Gebreyesus, Seifu H.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Biotechnology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Developmental Biology

description: Additional file 6: S Table 6. Growth chart for fetal femur length/biparietal diameter, Butajira Ethiopia, 2018-2019.
"Review of The Taming of the Shrew." Shakespeare Bulletin 35.4 (2017): 700-703
Creators: name: Joubin, Alexa Alice
Publisher: name: Humanities Commons
Year: 2017
Subjects: subject: Shakespeare, William, 1564-1616
subject: Performance art--Study and teaching
subject: Feminist criticism
subject: Theater
subject: United States
subject: American drama

description: Can we entertain the idea that The Taming of the Shrew can be performed and received as comedy in the post-Women’s March US? If so, would the laughter be empathetic and solidary rather than callous? The answer lies in physical theater which is uniquely poised to activate elements of farce in the play. Shrew is one of the Shakespearean comedies that tends to clash with modern sensibilities and is therefore generally considered challenging to stage. The Synetic Theater’s version reminds us that, after all, the foundation of this play is farce, a play-within-a-play to mock the worldview of Christopher Sly the drunkard and to entertain the impersonated lords who derive voyeuristic pleasure from watching Sly gawking at Shrew. The so-called play-within-a-play could also be a fanciful dream of the inebriated Sly. The Synetic Theater’s ninety-minute dance, musical, and visual feast rendered the comedy in vibrant colors—without spoken words. There was no induction or framing scene, though a fair amount of extratextual material had been introduced.
Additional file 1 of Latent antibiotic resistance genes are abundant, diverse, and mobile in human, animal, and environmental microbiomes
Creators: name: Inda-Díaz, Juan Salvador
name: Lund, David
name: Parras-Moltó, Marcos
name: Johnning, Anna
name: Bengtsson-Palme, Johan
name: Kristiansson, Erik
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1 shows the number of metagenomic samples per environment included in the study. Table S2 shows the results for the assessment of higher and lower abundance and diversity of the established ARGs compared to the latent ones for each antibiotic class. Table S3 shows the results for the assessment of over- and under-representation of ARGs in the core-resistomes compared to their corresponding pan-resistome for each antibiotic type. Table S4 shows the number of ARGs in the pan- and core-resistomes for each environment and gene class.
sj-docx-3-sjp-10.1177_14034948211024483 – Supplemental material for One Health practices across key agencies in Sweden – Uncovering barriers to cooperation, communication and coordination
Creators: name: Humboldt-Dachroeden, Sarah
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-docx-3-sjp-10.1177_14034948211024483 for One Health practices across key agencies in Sweden – Uncovering barriers to cooperation, communication and coordination by Sarah Humboldt-Dachroeden in Scandinavian Journal of Public Health
Additional file 2 of Latent antibiotic resistance genes are abundant, diverse, and mobile in human, animal, and environmental microbiomes
Creators: name: Inda-Díaz, Juan Salvador
name: Lund, David
name: Parras-Moltó, Marcos
name: Johnning, Anna
name: Bengtsson-Palme, Johan
name: Kristiansson, Erik
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Figure S1 shows the principal component analysis (PCA) of the α-diversity of latent and established ARGs. Figures 2 and 3 correspond to the distribution of the log-transformed relative abundance and α-diversity of latent and established ARGs for each gene class and environment. Figure S2 shows the host-associated metagenomes and Figure S3 the external environments. Aquatic includes samples from fresh, lentic, and marine water; Plants includes rhizosphere samples; Infants include samples from their digestive system; Wastewater includes activated sludge, water and sludge, fecal source, and raw wastewater; Terrestrial includes soil samples; Human includes samples from the skin, digestive and respiratory systems; Birds includes samples from their digestive system; and Mammals includes samples from the digestive systems of bovines, mice, and pigs. RPG is short for ribosomal protection gene. Figure 4 shows the correlation between the abundance of latent and establish ARGs for each gene class and environment. The color intensity reflects the size of the estimated correlation coefficient and an asterisk (*) marks significant correlations (p<0.001). Gray squares indicate environment and gene classes with an insufficient number of non-zero observations to calculate the correlation coefficient and/or the p-value.
Una piattaforma web per l'indagine storica. Grafici e fotografi pubblicitari in Pubblicit� in Italia tra gli anni Cinquanta e Settanta.
Creators: name: DEL ZOTTO, LUCIA
Publisher: name: Universit� IUAV di Venezia
Year: 2020

description: L?oggetto di indagine considerato nella ricerca � il rapporto tra grafici e fotografi in Italia tra gli anni Cinquanta e Settanta all'interno della produzione di artefatti pubblicitari a stampa. Prendere in esame, osservare e indagare tali relazioni ha significato identificare i protagonisti e ricostruire una vicenda lacunosa e dimenticata dalla storiografia ufficiale. L'indagine, svolta grazie alla combinazione di dati quantitativi, fonti secondarie e materiali d?archivio, intende offrire un resoconto ragionato sul dialogo che fotografia e grafica hanno affrontato in ambito pubblicitario. Si tratta dunque di un viaggio teso a ricostruire una cartografia, dai tracciati multipli, che si propone non solo di portare alla luce le relazioni fra grafici e fotografi ma anche quelle intercorse fra altre figure professionali coinvolte e i loro committenti, delineando il clima culturale e storico in cui si sono consolidate queste collaborazioni e aprendo la strada per possibili ricerche future sulla tematica.
Attraverso la digitalizzazione della pubblicazione Pubblicit� in Italia: Suggestioni Pubblicitarie, edita dal 1953 al 1987 dall'Ufficio Moderno, � stata sviluppata la piattaforma www.pubblicitainitalia.com. Creata come supporto alla ricerca storica, diventa un tool open source utilizzabile e implementabile per ulteriori ricerche, permettendo inoltre la verifica e l'incrocio dei dati con quelli provenienti dagli archivi e dalla letteratura di settore. L?ampia quantit� di dati digitalizzati ha permesso di rilevare pattern, ricorrenze e relazioni con l'obiettivo di elaborare osservazioni storiche su di essi. Sono state cos� identificate tre fasi, la prima dal 1953 al 1960, la seconda dal 1961 al 1970 e la terza dal 1971 al 1980, ognuna delle quali riflette su determinati nodi storici che intersecano grafica e fotografia.
Additional file 1 of Development and external validation of a diagnostic model for cardiometabolic-based chronic disease : results from the China health and retirement longitudinal study (CHARLS)
Creators: name: Li, Yong
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional File 1: Checklist of items to include when reporting a study developing or validating a multivariable prediction model for diagnosis or prognosis*
Modeling Granular Material Mixing and Segregation Using a Finite Element Method and Advection-Diffusion-Segregation Equation Multi-Scale Model
Creators: name: Liu, Yu
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified

description: Granular material blending plays an important role in many industries ranging from those that manufacture pharmaceuticals to those producing agrochemicals. The ability to create homogeneous powder blends can be critical to the final product quality. For example, insufficient blending of a pharmaceutical formulation may have serious consequences on product efficacy and safety. Unfortunately, tools for quantitatively predicting particulate blending processes are lacking. Most often, parameters that produce an acceptable degree of blending are determined empirically. The objective of this work was to develop a validated model for predicting the magnitude and rate of granular material mixing and segregation for binary mixtures of granular material in systems of industrial interest. The model utilizes finite element method simulations to determine the bulk-level granular velocity field, which is then combined with particle-level diffusion and segregation correlations using the advection-diffusion-segregation equation. An important factor to the success of the finite element method simulation used in the current work is the material constitutive model used to represent the granular flow behavior. In this work, the Mohr-Coulomb elastoplastic (MCEP) model was used. The MCEP model parameters were calibrated both numerically and experimentally and the procedure is described in the current work. Additionally, the particle-level diffusion and segregation correlations are important to the accurate prediction of mixing and segregation rates. The current work derived the diffusion and segregation correlations from published literature and determined a methodology for obtaining the particle diffusion and segregation parameters from experiments. The utility of this modelling approach is demonstrated by predicting mixing patterns in a rotating drum and Tote blender as well as segregation patterns in a rotating drum and during the discharge of conical hoppers. Indeed, a significant advantage of the current modeling approach compared to previously published models is that arbitrary system geometries can be modeled. The model predictions were compared with both DEM simulation and experiment results. The model is able to quantitatively predict the magnitude and rate of powder mixing and segregation in two- and three-dimensional geometries and is computationally faster than DEM simulations. Since the numerical approach does not directly model individual particles, this new modeling approach is well suited for predicting mixing and segregation in large industrial-scale systems.
ENGL 521: Nineteenth-Century Speculative Fiction
Creators: name: Whitson, Roger
Publisher: name: unknown
Year: 2018
Subjects: subject: English literature
subject: Nineteenth century
subject: Science
subject: Romanticism
subject: Ecology
subject: FOS: Biological sciences
subject: Science fiction

description: Darko Suvin claims that science fiction is fundamentally concerned with "cognitive estrangement," or the presence of some element in the story that transforms how its readers understand their world. In fact, much of the developments in science, economics, and politics in the nineteenth century were also concerned with the new worlds revealed by an increasingly industrialized society. Charles Darwin shocked the world by postulating that natural selection determined the habits of human beings, not any divine plan. Voyages to other parts of the planet were revealing new frontiers and new spaces for capitalism and colonialism to exploit. Machines and unskilled labor were replacing artisans with mechanized and standardized commodities. And the hopes and fears inspired by these new worlds reappeared as dreams and nightmares in speculative fiction: Darwin's theories became the strange human-like animal hybrids of H.G. Wells's The Island of Dr. Moreau, while imperialism inspired the "lost race" novels of H. Rider Haggard and made possible the utopian dreams of William Morris and Charlotte Perkins Gilman.

This course will show how science fiction articulated the hopes and fears Victorians associated with the future. Such anxieties are a symptom of our inability to imagine the future (or the past) in its alterity. Against liberal promises of perpetual progress in which the notion of eventual inclusion tells the oppressed to stave off revolution and reassure the ruling class, science fiction enacts dramas surrounding the true danger and possibility of a future that is entirely unpredictable. In addition to the authors mentioned above, this course will show how women and authors of color used science fiction to challenge the oppressions of their day and imagine futures that asserted their freedom and power.
ENGL 521: Nineteenth-Century Speculative Fiction
Creators: name: Whitson, Roger
Publisher: name: Humanities Commons
Year: 2018
Subjects: subject: Science
subject: Science fiction
subject: Ecology
subject: FOS: Biological sciences
subject: English literature
subject: Nineteenth century
subject: Romanticism

description: Darko Suvin claims that science fiction is fundamentally concerned with “cognitive estrangement,” or the presence of some element in the story that transforms how its readers understand their world. In fact, much of the developments in science, economics, and politics in the nineteenth century were also concerned with the new worlds revealed by an increasingly industrialized society. Charles Darwin shocked the world by postulating that natural selection determined the habits of human beings, not any divine plan. Voyages to other parts of the planet were revealing new frontiers and new spaces for capitalism and colonialism to exploit. Machines and unskilled labor were replacing artisans with mechanized and standardized commodities. And the hopes and fears inspired by these new worlds reappeared as dreams and nightmares in speculative fiction: Darwin’s theories became the strange human-like animal hybrids of H.G. Wells’s The Island of Dr. Moreau, while imperialism inspired the “lost race” novels of H. Rider Haggard and made possible the utopian dreams of William Morris and Charlotte Perkins Gilman.   This course will show how science fiction articulated the hopes and fears Victorians associated with the future. Such anxieties are a symptom of our inability to imagine the future (or the past) in its alterity. Against liberal promises of perpetual progress in which the notion of eventual inclusion tells the oppressed to stave off revolution and reassure the ruling class, science fiction enacts dramas surrounding the true danger and possibility of a future that is entirely unpredictable. In addition to the authors mentioned above, this course will show how women and authors of color used science fiction to challenge the oppressions of their day and imagine futures that asserted their freedom and power.
title: Oranger Trifolié :
title: Principes directeurs pour la conduite de l’examen de la distinction, de l’homogénéité et de la stabilité.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants..,
Publisher: name: International Union for the Protection of New Varieties of Plants
Year: 0
Subjects: Group identity.
New Varieties of Plants
Trifoliate Orange

description: Ces principes directeurs (“principes directeurs d’examen”) visent à approfondir les principes énoncés dans l’introduction générale (document TG/1/3) et dans les documents TGP qui s’y rapportent afin de donner des indications concrètes détaillées pour l’harmonisation de l’examen de la distinction, de l’homogénéité et de la stabilité (DHS) et, en particulier, à identifier des caractères convenant à l’examen DHS et à la production de descriptions variétales harmonisées.
“Le plus parisien de tous les nègres:” Victor Cochinat et l’expérience de la couleur
Creators: name: liseschreier
Publisher: name: Humanities Commons
Year: 2018
Subjects: subject: French literature

description: Victor Cochinat, chroniqueur au Nain Jaune, au Figaro, au Petit Journal, ennemi invétéré de Verlaine, Rimbaud et Fantin-Latour––qui le surnommaient « Cochinat-Bamboula »––a été entre 1850 et 1880 l’un des piliers de la bohême parisienne. Ce Martiniquais, qui ripaillait avec cochers et ouvriers imprimeurs comme avec peintres et écrivains, se déboutonnait avec des femmes des faubourgs et trichait au billard au nez et à la barbe de commissaires de police, a suscité de son vivant de grands mouvements de sympathie. A sa mort, de multiples nécrologies ont attesté que sa qualité première était « son esprit du plus pur parisien... du plus fin boulevardier » ; ses amis, eux, ont pleuré « le plus parisien de tous les nègres ». A une époque où expositions universelles, romans populaires, théâtre et autres productions culturelles justifiaient l’entreprise coloniale, comment deux catégories tenues pour distinctes, celle du « Parisien » et celle du « Nègre », sont-elles devenues complémentaires ? L’histoire de Cochinat nous en apprend long sur les façons dont ses contemporains ont négocié l’idée de race telle qu’elle leur était alors présentée d’une part, et l’expérience d’un quotidien partagé avec un homme de couleur d’autre part. Elle nous permet aussi de voir comment un écrivain de couleur s’est situé dans les débats liés aux questions raciales, comment il y a contribué, et s’en est dégagé. Elle nous permet enfin de considérer trois regards, celui des contemporains de Cochinat, le sien, mais aussi le nôtre, qu’il importe de perpétuellement recalibrer.
sj-docx-1-las-10.1177_00238309211010859 – Supplemental material for No, No One Had Fun. Individual Differences in Nonliteral Language Perception
Creators: name: Joergensen, Gitte Henssel
name: Makarla, Pavitra Rao
name: Fammartino, Matthew
name: Benson, Lauren
name: Rothermich, Kathrin
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: Education
subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-1-las-10.1177_00238309211010859 for No, No One Had Fun. Individual Differences in Nonliteral Language Perception by Gitte Henssel Joergensen, Pavitra Rao Makarla, Matthew Fammartino, Lauren Benson and Kathrin Rothermich in Language and Speech
sj-pdf-2-hsx-10.1177_10887679211018492 – Supplemental material for The Crisis of Social Institutions and Police Homicides: The Adverse Effects of Low Institutional Control
Creators: name: Wetherell, Kamali’ilani T. E.
name: Miethe, Terance D.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, sj-pdf-2-hsx-10.1177_10887679211018492 for The Crisis of Social Institutions and Police Homicides: The Adverse Effects of Low Institutional Control by Kamali’ilani T. E. Wetherell and Terance D. Miethe in Homicide Studies
Development of New Drugs for the Treatment of Oral Cancers
Creators: name: AKELLA, PRASANTH SARASWATI
Publisher: name: Universit� degli Studi di Siena
Year: 2020

description: Le terapie epigenetiche rappresentano una delle aree pi� promettenti e innovative della scienza moderna. In particolare, l'uso di inibitori delgli enzimi della famiglia histone deacetylases (HDAC) 'HDAC ha acquisito un notevole interesse come strumenti terapeutici grazie al successo dell'approvazione della FDA di quattro farmaci. Tuttavia, a causa della natura pan-inibitoria di questi composti e dei loro effetti collaterali, vi � un urgente bisogno di identificare inibitori selettivi delle differenti isoforme. A questo proposito, l'unicit� dell'isoforma HDAC6 ha attirato l'attenzione diffusa su vari programmi di scoperta di farmaci. A differenza di altre isoforme HDAC, HDAC6 contiene due domini catalitici e quindi agisce sia su substrati istonici che non-istonici. La sovraespressione di HDAC6 � stata collegata a molte condizioni patologiche come cancro, neurodegenerazione, autoimmunit�, malattie infettive e disturbi rari. Inoltre, recenti studi che evidenziano la bassa incidenza di letalit� nei modelli di topi knockout per HDAC6 sottolinea i benefici dell'uso di inibitori selettivi di HDAC6 rispetto agli inibitori pan o parzialmente selettivi. Sulla base di questi fatti, molti gruppi di ricerca hanno sviluppato attivamente numerosi inibitori selettivi dell'HDAC6 per varie terapie.
Questo lavoro di tesi si concentra sulla porgettazione razionale, fatta presso il notro laboratirrio di chimica computazionale, sullo studio delle ralazioni struttura-affinit� (SAR) sulla sintesi e lo svuluppo di nuovi inibitori potenti e selettivi per HDAC6 come agenti antitumorali. Saranno anche discussi i risultatii ottenuti relativamente agli studi a raggi X e alla valutazione biologica dei composti sviluppati e oggetto del presente lavoro di tesi. In particolare, sulla base della struttura modulare deio composti sviluppati, sono stati sintetizzati due nuovi ?cap-groups? che hanno consentito l?inserimento di diverse decorazioni per ottenere elevata potenza e selettivit� nei confronti di HDAC6. I composti con le migliori prestazioni sono stati sottoposti a screening in varie linee cellulari tumorali per valutarne la loro citotossicit�, i loro effetti sul ciclo cellulare e il potenziale pro-apoptotico. Inoltre, sulla base dei rapporti che indicano l'uso di inibitori di HDAC6 su STAT3, alcuni dei composti sono stati valutati per la loro attivit� inibitoria su STAT3. Inoltre, � stato valuatato il potenziale di mutagenicit� e citotossicit� per i composti per determinare il loro profilo di sicurezza e tossicit�. In conclusione, questo lavoro ha consentito lo sviluppo di una nuova serie di inibitori potenti e selettivi per HDAC6 come agenti antitumorali dotati di promettenti profili terapeutici.
La funzione Saba
Creators: name: TASCA, MATTEO
Publisher: name: Universit� degli Studi di Siena
Year: 2021

description: La tesi si propone di analizzare la poetica sabiana e la ricezione della sua opera tra primo e secondo dopoguerra, mettendone in evidenza gli elementi di maggiore modernit�, e verificando i modi in cui � stata ripresa dai poeti del secondo Novecento, in particolare Penna e Sereni.
Additional file 1 of Intramedullary spinal cord metastasis from esophageal squamous cell carcinoma: case report and literature review
Creators: name: Shen, Beiduo
name: Ba, Zhaoyu
name: Huang, Yufeng
name: Wu, Desheng
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Cancer
subject: Mental Health

description: Additional file 1.
A Flexible Mixed Reality Simulation Framework for Software Development in Robotics
Creators: name: Chen, Ian Yen Hung
name: Macdonald, Bruce
name: Wuensche, Burkhard
Publisher: name: Universit� degli studi di Bergamo
Year: 2011

description: In recent years robots have dramatically improved in functionality, but as a result their designs have also become more complicated. The increase in the complexity of the tasks and the design of the robot result in a challenging and time-consuming robot development cycle. This paper identifies requirements for improving the robot development process, focusing on facilitating a safe and reliable transition process from simulation to real world tests. We propose that, by applying the concept of Mixed Reality (MR) to robot simulation, it is possible to create a realistic, synthetic environment that enables robot software developers to experiment freely and safely. The new simulation approach, named MR simulation, offers the flexibility of creating simulation environments composed of real and virtual objects that seamlessly interact with one another. This paper contributes a generic, conceptual MR framework which is demonstrated to provide a common, standardised simulation environment for experimentation involving real and virtual objects. An MR robot simulator is implemented based on the framework, integrating standardised data interfaces in its design to increase interoperability. Evaluation results demonstrate that the MR robot simulator is reusable in three different applications. It improved simulation reliability, reduced development cost, and increased efficiency.
Jude the liminal: A catastrophic pursuit?
Creators: name: Gocmen, Gulsah
Publisher: name: Humanities Commons
Year: 2017
Subjects: subject: English fiction
subject: Nineteenth century
subject: Group identity
subject: Literature and anthropology

description: Thomas Hardy's last novel Jude the Obscure (1895) is centred on its working-class protagonist Jude Fawley's efforts first to become a scholar, then his experiences of resisting the orthodoxies of his society and lastly defying Christianity as a restrictive social force on the individuals. This paper aims to discuss Jude's liminal character from the cultural perspectives on liminality respectively developed by the French ethnographer Arnold van Gennep and the British cultural anthropologist Victor Turner. Jude as a liminal character experiences similar transitions or rites of passage as defined and categorized by van Gennep. Yet, Jude's liminality remains permanent in each stage of his life since he cannot thoroughly perform the transition rites to leave one social position behind and undertake a new one. Also, analysed as a liminal character from Turner's understanding of the term, Jude fails to use the potential that his liminality provides him with to challenge the societal dogmas. However, he terribly suffers from the consequences of his liminal identity throughout the story. Jude's tragic end displays how he is punished for his lifelong liminality that prevents him from moving either to the centre or the margins of his Victorian society. This essay argues that Hardy's portrayal of Jude as a liminal figure reminds the defnitions of the term, developed by van Gennep and Turner, but produces a literary example that is quite antithetical to their conceptions particularly due to his apparent pessimism. For, Hardy depicts Jude's threshold identity as an obstacle in his efforts to belong to any particular social, cultural, economic, or intellectual group rather than an opportunity to challenge each social position.
Additional file 1 of Rare diseases: why is a rapid referral to an expert center so important?
Creators: name: Willmen, Tina
name: Willmen, Lukas
name: Pankow, Anne
name: Ronicke, Simon
name: Gabriel, Heinz
name: Wagner, Annette Doris
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Efficient Query Processing Over Web-Scale RDF Data
Creators: name: Madkour, Amgad M.
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Applied computing not elsewhere classified

description: The Semantic Web, or the Web of Data, promotes common data formats for representing structured data and their links over the web. RDF is the defacto standard for semantic data where it provides a flexible semi-structured model for describing concepts and relationships. RDF datasets consist of entries (i.e, triples) that range from thousands to Billions. The astronomical growth of RDF data calls for scalable RDF management and query processing strategies. This dissertation addresses efficient query processing over web-scale RDF data. The first contribution is WORQ, an online, workload-driven, RDF query processing technique. Based on the query workload, reduced sets of intermediate results (or reductions, for short) that are common for specific join pattern(s) are computed in an online fashion. Also, we introduce an efficient solution for RDF queries with unbound properties. The second contribution is SPARTI, a scalable technique for computing the reductions offline. SPARTI utilizes a partitioning schema, termed SemVP, that enables efficient management of the reductions. SPARTI uses a budgeting mechanism with a cost model to determine the worthiness of partitioning. The third contribution is KC, an efficient RDF data management system for the cloud. KC uses generalized filtering that encompasses both exact and approximate set membership structures that are used for filtering irrelevant data. KC defines a set of common operations and introduces an efficient method for managing and constructing filters. The final contribution is semantic filtering where data can be reduced based on the spatial, temporal, or ontological aspects of a query. We present a set of encoding techniques and demonstrate how to use semantic filters to reduce irrelevant data in a distributed setting.
Numerical modelling strategies and design methods for timber structures
Creators: name: FRANCO, LUCA
Publisher: name: Universit� IUAV di Venezia
Year: 2020

description: Over the last years timber constructions are gaining back a primary role in the building industry after decades in which they were almost abandoned in favor of concrete and steel structures. A sign of this change is the appearance in the last years in many Italian universities of courses dedicated to the design of timber structures. One of the main reasons behind this success must be sought in the development of new engineered timber materials, such as glued-laminated and cross-lam timber, that allowed to wooden structures to reach structural potentialities that until some decades ago were prerogative of concrete or steel building materials. Tests recently carried out on full-scale buildings have also proven the excellent capabilities of these new timber technologies in providing reliable and highly-performant multi-storey building able to withstand high seismic intensities.
Since the employment of timber to build multi-storey buildings in seismic-prone areas is quite recent, many aspects relating the understanding of their structural behavior and their correct design are still to be sought, as demonstrated by the lack of provisions in current building codes and standards and the still ongoing great amount of research activity on seismic behavior of timber structures.
Modern timber technologies also allow to cover very large spans with long glued-laminated timber beams, satisfying the need of large open spaces and architectural flexibility required by modern building design approaches. These bulky big-size elements anyway result quite expensive in production, transportation and installation phases undermining the economic competitiveness of timber structures. To cope with this problem, the prototype of an innovative timber-steel composite beam consisting of sub-elements assembled on-site to create longer members has been ideated at KTH Royal Institute of Technology of Stockholm in Sweden.
One of the objectives of this thesis is therefore to provide an advance in the state of knowledge of timber building technology adopted for seismic-prone areas, focusing in particular on both numerical modelling strategies and design methods for cross-laminated timber buildings, illustrated respectively in the first and second part of the thesis. The other goal is the development of an analytical tool for the enhancement and the investigation of the structural performances of the innovative composite beam ideated at KTH Royal Institute of Technology, and it will be exposed in the third and last part of the thesis.
Der einheitliche Spenderfragebogen
Creators: name: Offergeld, Ruth
name: Heiden, Margarethe
name: Stötzer, Frank
name: Northoff, Hinnak
Publisher: name: Robert Koch-Institut
Year: 2011
Subjects: subject: Blutspenderfragebogen
subject: 610 Medizin

description: Seit Februar 2011 steht ein einheitlicher Blutspenderfragebogen für Blut- und Plasmaspender in Deutschland zur Verfügung. Dieser wurde im Auftrag des Arbeitskreises Blut von einer Expertengruppe entwickelt. Der Fragebogen wendet wichtige Prinzipien der „Guten Fragebogenpraxis“ wie einfache, eindeutige Fragen, möglichst Verzicht auf Listen und klare Adressierung von Risiken für Transfusionsempfänger an.Eine Multicenterstudie mit 6.500 Neuspendern konnte zeigen, dass der einheitliche Fragebogen gegenüber den bislang verwendeten Fragebögen Vorteile zeigte. Insbesondere wurden die Fragen als verständlicher eingeschätzt und die Antworten stimmten mit denen im ärztlichen Gespräch überein. Es wurden 4,6 % mehr Neuspender nicht zur Spende zugelassen, vor allem wegen akuter Erkrankungen und Risiken für wichtige Infektionskrankheiten. Der Fragebogen wird in Zukunft kontinuierlich an die bestehenden Regelwerke angepasst. Er bietet somit einen sicheren Standard für Spendeeinrichtungen, die sich für seinen Einsatz entscheiden.
description: In February 2011 a uniform blood donor history questionnaire (DHQ) for Germany was published. This questionnaire was developed by a group of experts from the National Advisory Committee „Blood“. It includes key features like non medical language, short sentences, few lists (e.g. of diseases) and direct assessment of behaviour resulting in a in a potential risk for the recipient. The evaluation of the DHQ in a multi-centre trial with 6500 first time donors revealed that donors considered the new DQ as easier to understand than the established DQ. The given answers were in concordance with those made in the personal interview in all categories with new DQ. 4,6% additional deferrals were observed with new compared to established DQ. Deferrals more often were due to acute illness or sexual risk behaviour. The DHQ will be adapted continuously to the current regulations in the future. It therefore serves as a safe standard for blood establishments who decide to use it.
La permanencia de los trabajores con engermedades cronicas en el mercado de trabajo. Una perspectiva juridica
Creators: name: FERNANDEZ MARTINEZ, Silvia
Publisher: name: Universit� degli studi di Bergamo
Year: 2018

description: La tesi di dottorato intende studiare, attraverso un approccio multidisciplinare e comparato, il modo in cui il diritto del lavoro e i sistemi di welfare possono contribuire a promuovere la conservazione e il ritorno al lavoro dei lavoratori con malattie croniche. L?obbiettivo principale � quello di individuare vie alternative che consentano ai lavoratori con malattie croniche di continuare a lavorare in maniera compatibile con la loro capacit� lavorativa ridotta invece di abbandonare in maniera prematura il mercato del lavoro, principalmente attraverso il licenziamento per giustificato motivo oggettivo o perch� gli viene riconosciuta una pensione di invalidit� o inabilit� al lavoro. Il modo migliore per tutelare i malati cronici non � quello di equipararli ad altre figure giuridiche come la disabilit�, ma individuare tutele ad hoc. Queste tutele potrebbero consistere nel considerare la malattia cronica come una causa di discriminazione autonoma, il diritto all?adattamento delle condizioni di lavoro, una protezione specifica contro il licenziamento fondato nelle cause derivate dalla malattia e, infine, un cambio di prospettiva dei sistemi di welfare che dovrebbero supportare il lavoratore per un adeguato rientro al lavoro invece che promuovere la loro uscita prematura dal mercato di lavoro.
HIV-Prevalence in Tuberculosis Patients in Germany, 2002–2009: An Estimation Based on HIV and Tuberculosis Surveillance Data
Creators: name: Fiebig, Lena
name: Kollan, Christian
name: Hauer, Barbara
name: Gunsenheimer-Bartmeyer, Barbara
name: Heiden, Matthias An Der
name: Haas, Walter
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2012
Subjects: subject: Humans
subject: Female
subject: Male
subject: Adolescent
subject: Adult
subject: Aged
subject: Comorbidity
subject: Germany/epidemiology
subject: Middle Aged
subject: Anti-HIV Agents/therapeutic use
subject: Antitubercular Agents/therapeutic use
subject: HIV/pathogenicity
subject: HIV Infections/complications
subject: HIV Infections/epidemiology
subject: HIV Infections/virology
subject: HIV Seropositivity
subject: Prevalence
subject: Tuberculosis/complications
subject: Tuberculosis/epidemiology
subject: Tuberculosis/virology
subject: 610 Medizin

description: Tuberculosis (TB) and HIV comorbidity is a major challenge in TB prevention and control but difficult to assess in Germany as in other countries, where data confidentiality precludes notifying the HIV status of TB patients. We aimed to estimate the HIV-prevalence in TB patients in Germany, 2002–2009, and to characterize the HIV/TB patients demographically. Data from the long-term observational open multicentre cohort ClinSurv HIV were used to identify incident TB in HIV-positive individuals. We assessed the cohort’s coverage for the nationwide HIV-positive population by contrasting ClinSurv HIV patients under antiretroviral therapy (ART) with national HIV patient numbers derived from ART prescriptions (data by Insight Health; available for 2006–2009). The HIV-prevalence in TB patients was calculated as the number of HIV/TB cases projected for Germany over all culture-positive TB notifications. From 2002 to 2009, 298 of 15,531 HIV-positive patients enrolled in the ClinSurv HIV cohort were diagnosed with TB. A 21% cohort coverage was determined. The annual estimates of the HIV-prevalence in TB patients were on average 4.5% and ranged from 3.5% (95%CI 2.3–5.1%) in 2007 to 6.6% (95%CI 5.0–8.5%) in 2005. The most recent estimate for 2009 was 4.0% (95%CI 2.6–5.9%). The 298 HIV/TB patients were characterized by a male-to-female ratio of 2.1, by a median age of 38 years at TB diagnosis, and by 59% of the patients having a foreign origin, mainly from Subsahara Africa. We provide, to our knowledge, the first estimate of the HIVprevalence in TB patients for Germany by joint evaluation of anonymous HIV and TB surveillance data sources. The identified level of HIV in TB patients approximates available surveillance data from neighbouring countries and indicates a non-negligible HIV/TB burden in Germany. Our estimation approach is valuable for epidemiological monitoring of HIV/TB within the current legal frameworks.