cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Protein Adsorption into Mesopores: A Combination of Electrostatic Interaction, Counterion Release and van der Waals Forces
Creators: name: Moerz, Sebastian T.
name: Huber, Patrick
Publisher: name: arXiv
Year: 2015
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Bovine heart cytochrome c has been immobilized into the mesoporous silica host material SBA-15 in both its native folded and urea-unfolded state. The comparison of the two folding states' behavior casts doubt on the commonly used explanation of cytochrome c adsorption, i.e. the electrostatic interaction model. A detailed investigation of the protein binding as a function of pH and ionic strength of the buffer solution reveals the complex nature of the protein-silica interaction. Electrostatic interaction, van der Waals forces and entropic contributions by counterion release each contribute to adsorption on the silica pore walls.
description: 17 pages, 5 figures
Optical reconstruction of collective density matrix of qutrit
Creators: name: Kopciuch, Marek
name: Pustelny, Szymon
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Reconstruction of a quantum state is of prime importance for quantum-information science. Specifically, means of efficient determination of a state of atoms of room-temperature vapor may enable applications in quantum computations and cryptography. To step toward such applications, here we present a method of reconstruction of a collective density matrix of an atomic ensemble, consisting of atoms with an $F=1$ ground state. Such a long-lived state is often encountered in real systems (e.g., potassium, sodium, rubidium) and hence may be practically utilized. Our theoretical treatment enables derivation of explicit formulas relating optical signals (polarization rotation and ellipticity change) with specific density-matrix elements. The analysis are supported with numerical simulations, which allows to evaluate fidelity and robustness of the algorithm. The tests show that our algorithm allows to obtain the fidelity exceeded 0.95 even at noisy environment and/or significant atomic manipulation imperfections.
File S1 from Spatial separation of the cyanogenic β-glucosidase ZfBGD2 and cyanogenic glucosides in the haemolymph of Zygaena larvae facilitates cyanide release
Creators: name: Pentzold, Stefan
name: Jensen, Mikael Kryger
name: Matthes, Annemarie
name: Olsen, Carl Erik
name: Petersen, Bent Larsen
name: Clausen, Henrik
name: Møller, Birger Lindberg
name: Bak, Søren
name: Zagrobelny, Mika
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biochemistry
subject: Evolutionary Biology
subject: FOS: Biological sciences

description: Western blot methods
Challenging the innovation imperative. Libraries empower a collaborative ecosystem
Creators: name: Holmes, Kristi
Publisher: name: Zenodo
Year: 2020
Subjects: InvenioRDM
innovation
maintenance
libraries
biomedicine

description: Mobilizing Computable Biomedical Knowledge 2020 Annual Meeting (virtual) Presentation in CBK and the Library of the Future: Anticipating the Second Knowledge Revolution panel Panelists: Kristi Holmes Northwestern University, Violeta Ilik Columbia University, Jeff Oliver University of Arizona, and Bart Ragon University of Virginia Moderated by Chris Shaffer UC San Francisco & Terrie Wheeler Weill Cornell Medicine
PROSPECT-II Physics Opportunities
Creators: name: Andriamirado, M.
name: Balantekin, A. B.
name: Band, H. R.
name: Bass, C. D.
name: Bergeron, D. E.
name: Bowden, N. S.
name: Bryan, C. D.
name: Carr, R.
name: Classen, T.
name: Conant, A. J.
name: Deichert, G.
name: Delgado, A.
name: Diwan, M. V.
name: Dolinski, M. J.
name: Erickson, A.
name: Foust, B. T.
name: Gaison, J. K.
name: Galindo-Uribari, A.
name: Gilbert, C. E.
name: Grant, C.
name: Hans, S.
name: Hansell, A. B.
name: Heeger, K. M.
name: Heffron, B.
name: Jaffe, D. E.
name: Jayakumar, S.
name: Ji, X.
name: Jones, D. C.
name: Koblanski, J.
name: Kunkle, P.
name: Kyzylova, O.
name: Lane, C. E.
name: Langford, T. J.
name: LaRosa, J.
name: Littlejohn, B. R.
name: Lu, X.
name: Maricic, J.
name: Mendenhall, M. P.
name: Meyer, A. M.
name: Milincic, R.
name: Mueller, P. E.
name: Mumm, H. P.
name: Napolitano, J.
name: Neilson, R.
name: Nikkel, J. A.
name: Nour, S.
name: Palomino, J. L.
name: Pushin, D. A.
name: Qian, X.
name: Rosero, R.
name: Searles, M.
name: Surukuchi, P. T.
name: Tyra, M. A.
name: Varner, R. L.
name: Venegas-Vargas, D.
name: Weatherly, P. B.
name: White, C.
name: Wilhelmi, J.
name: Woolverton, A.
name: Yeh, M.
name: Zhang, C.
name: Zhang, X.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The Precision Reactor Oscillation and Spectrum Experiment, PROSPECT, has made world-leading measurements of reactor antineutrinos at short baselines. In its first phase, conducted at the High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory, PROSPECT produced some of the strongest limits on eV-scale sterile neutrinos, made a precision measurement of the reactor antineutrino spectrum from $^{235}$U, and demonstrated the observation of reactor antineutrinos in an aboveground detector with good energy resolution and well-controlled backgrounds. The PROSPECT collaboration is now preparing an upgraded detector, PROSPECT-II, to probe yet unexplored parameter space for sterile neutrinos and contribute to a full resolution of the Reactor Antineutrino Anomaly, a longstanding puzzle in neutrino physics. By pressing forward on the world's most precise measurement of the $^{235}$U antineutrino spectrum and measuring the absolute flux of antineutrinos from $^{235}$U, PROSPECT-II will sharpen a tool with potential value for basic neutrino science, nuclear data validation, and nuclear security applications. Following a two-year deployment at HFIR, an additional PROSPECT-II deployment at a low enriched uranium reactor could make complementary measurements of the neutrino yield from other fission isotopes. PROSPECT-II provides a unique opportunity to continue the study of reactor antineutrinos at short baselines, taking advantage of demonstrated elements of the original PROSPECT design and close access to a highly enriched uranium reactor core.
Agrobacterium rhizogenes mutants that fail to bind to plant cells.
Creators: name: Robertson Crews, J. L.
name: Matthysse, A. G.
name: Colby, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1990

description: Transposon insertion mutants of Agrobacterium rhizogenes were screened to obtain mutant bacteria that failed to bind to carrot suspension culture cells. A light microscope binding assay was used. The bacterial isolates that were reduced in binding to carrot cells were all avirulent on Bryophyllum diagremontiana leaves and on carrot root disks. The mutants did not appear to be altered in cellulose production. The composition of the medium affected the ability of the parent and mutant bacteria to bind to carrot cells. The parent strain bound to carrot cells in greatest numbers in low-ionic-strength media such as 4% sucrose but still showed significant binding in Murashige-Skoog tissue culture medium. All of the mutants showed reduced binding in 4% sucrose after 2 h of incubation with carrot cells. One mutant was delayed in binding in 4% sucrose. This mutant and one other mutant also showed reduced binding to carrot cells in Murashige-Skoog medium. To determine whether the Tn5 insertion was responsible for the mutant phenotype, DNA containing the Tn5 insertion was cloned from the mutant bacteria and used to introduce Tn5 into the parent strain in the same location as in the original mutant by marker exchange. The resulting transconjugants had the same avirulent, nonattaching phenotype as the original mutants, suggesting that the mutant phenotype was due to the Tn5 insertion. The cloned DNA containing the Tn5 insertion was also tested for homology to DNA of known genes that affect attachment of Agrobacterium tumefaciens to plant cells by DNA hybridization. No homology to chv, att, or pscA clones was observed. In addition, cloned chv, att, and pscA genes from A. tumefaciens were unable to complement the attachment-minus A. rhizogenes mutants. Thus, the A. rhizogenes nonattaching mutants appear to be different from the previously described A. tumefaciens mutants.
Exponential and Weibull models for spherical and spherical-shell diffusion-controlled release systems with semi-absorbing boundaries
Creators: name: Carr, Elliot J.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We consider the classical problem of particle diffusion in $d$-dimensional radially-symmetric systems with absorbing boundaries. A key quantity to characterise such diffusive transport is the evolution of the proportion of particles remaining in the system over time, which we denote by $\mathcal{P}(t)$. Rather than work with analytical expressions for $\mathcal{P}(t)$ obtained from solution of the corresponding continuum model, which when available take the form of an infinite series of exponential terms, single-term low-parameter models are commonly proposed to approximate $\mathcal{P}(t)$ to ease the process of fitting, characterising and interpreting experimental release data. Previous models of this form have mainly been developed for circular and spherical systems with an absorbing boundary. In this work, we consider circular, spherical, annular and spherical-shell systems with absorbing, reflecting and/or semi-absorbing boundaries. By proposing a moment matching approach, we develop several simple one and two parameter exponential and Weibull models for $\mathcal{P}(t)$, each involving parameters that depend explicitly on the system dimension, diffusivity, geometry and boundary conditions. The developed models, despite their simplicity, agree very well with values of $\mathcal{P}(t)$ obtained from stochastic model simulations and continuum model solutions.
description: 17 pages, 4 figures, accepted version
recA and catalase in H2O2-mediated toxicity in Neisseria gonorrhoeae.
Creators: name: Charniga, L.
name: Cohen, M. S.
name: Hassett, D. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1990

description: Neisseria gonorrhoeae cells defective in the biosynthesis of the recA gene product are no more sensitive to hydrogen peroxide than wild-type cells. Although gonococci possess nearly 100-fold-greater catalase levels than Escherichia coli, they are more susceptible to hydrogen peroxide than this organism. The natural niche of gonococci undoubtedly results in exposure to oxidant stress; however, they do not demonstrate particularly efficient antioxidant defense systems.
Involvement of a vitronectin-like protein in attachment of Agrobacterium tumefaciens to carrot suspension culture cells.
Creators: name: Matthysse, A. G.
name: Wagner, V. T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1992

description: Infections of dicotyledonous plants by Agrobacterium tumefaciens result in the formation of crown gall tumors. Attachment of the bacteria to plant host cells is required for tumor formation. Human vitronectin and antivitronectin antibodies both inhibited the binding of A. tumefaciens to carrot cells. Wild-type bacteria are able to bind radioactive vitronectin; nonattaching mutants showed a reduction in the ability to bind vitronectin. The binding of biotype 1 A. tumefaciens to carrot cells or to radioactive vitronectin was not affected by high ionic strength. Detergent extraction of carrot cells removed the receptor to which the bacteria bind. The extract was found to contain a vitronectin-like protein. These results suggest that A. tumefaciens utilizes a vitronectin-like protein on the plant cell surface as the receptor for its initial attachment to host cells.
{epub download} 100 Animals That Can F*cking End You by Mamadou Ndiaye
Creators: name: Paulsen
Publisher: name: Zenodo
Year: 2024

description: 100 Animals That Can F*cking End You by Mamadou Ndiaye

 

 

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100 Animals That Can F*cking End You

Mamadou Ndiaye

Page: 224

Format: pdf, ePub, mobi, fb2

ISBN: 9780316453776

Publisher: Little, Brown and Company

 

Pdf download books for free 100 Animals That Can F*cking End You 9780316453776

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Thin accretion discs around spherically symmetric configurations with nonlinear scalar fields
Creators: name: Stashko, O. S.
name: Zhdanov, V. I.
name: Alexandrov, A. N.
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study stable circular orbits (SCO) around static spherically symmetric configuration of General Relativity with a non-linear scalar field (SF). The configurations are described by solutions of the Einstein-SF equations with monomial SF potential $V(ϕ)=|ϕ|^{2n}$, $n>2$, under the conditions of the asymptotic flatness and behavior of SF $ϕ\sim 1/r$ at spatial infinity. We proved that under these conditions the solution exists and is uniquely defined by the configuration mass $M>0$ and scalar "charge" $Q$. The solutions and the space-time geodesics have been investigated numerically in the range $n\le40$, $|Q|\le 60$, $M\le60$. We focus on how nonlinearity of the field affects properties of SCO distributions (SCOD), which in turn affect topological form of the thin accretion disk around the configuration. Maps are presented showing the location of possible SCOD types for different $M,Q,n$. We found many differences from the Fisher-Janis-Newman-Winicour metric (FJNW) dealing with the linear SF, though basic qualitative properties of the configurations have much in common with the FJNW case. For some values of $n$, a topologically new SCOD type was discovered that is not available for the FJNW metric. All images of accretion disks have a dark spot in the center (mimicking an ordinary black hole), either because there is no SCO near the center or because of the strong deflection of photon trajectories near the singularity.
Multi-frequency, Multi-Epoch Study of Mrk 501: Hints for a two-component nature of the emission
Creators: name: Shukla, A.
name: Chitnis, V. R.
name: Singh, B. B.
name: Acharya, B. S.
name: Anupama, G. C.
name: Bhattacharjee, P.
name: Britto, R. J.
name: Mannheim, K.
name: Prabhu, T. P.
name: Saha, L.
name: Vishwanath, P. R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Since the detection of very high energy (VHE) $γ$-rays from Mrk 501, its broad band emission of radiation was mostly and quite effectively modeled using one zone emission scenario. However, broadband spectral and flux variability studies enabled by the multiwavelength campaigns carried out during the recent years have revealed rather complex behavior of Mrk 501. The observed emission from Mrk 501 could be due to a complex superposition of multiple emission zones. Moreover new evidences of detection of very hard intrinsic $γ$-ray spectra obtained from {\it Fermi}--LAT observations have challenged the theories about origin of VHE $γ$-rays. Our studies based on {\it Fermi}--LAT data indicate the existence of two separate components in the spectrum, one for low energy $γ$-rays and the other for high energy $γ$-rays. Using multiwaveband data from several ground and space based instruments, in addition to HAGAR data, the spectral energy distribution of Mrk~501 is obtained for various flux states observed during 2011. In the present work, this observed broadband spectral energy distribution is reproduced with a leptonic, multi-zone Synchrotron Self-Compton model.
description: Published in Astrophysical Journal (ApJ)
Gonococcal transferrin-binding protein 2 facilitates but is not essential for transferrin utilization.
Creators: name: Sparling, P. F.
name: Cornelissen, C. N.
name: Anderson, J. E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: Pathogenic Neisseria species have been shown to scavenge iron from transferrin (Tf), although the mechanism is not yet fully understood. Two iron-repressible proteins that exhibit Tf-binding activity have been identified. This work describes the cloning and sequencing of tbpB, a 2.1-kb gene in N. gonorrhoeae that encodes Tbp2, an 85-kDa iron-repressible lipoprotein. Transcriptional interruption of tbpB had a strong polar effect on tbpA, the structural gene for Tbp1 that is located immediately downstream from tbpB. Such tbpB mutants did not express either Tbp2 or Tbp1, did not bind Tf to whole cells, did not grow on Tf plates, and did not take up iron from Tf. A mutant in which most of tbpB was deleted, presumably leaving tbpA under transcriptional control of the tbpB promoter, was constructed. This mutant did not express Tbp2 but expressed wild-type levels of Tbp1 and possessed the phenotype of reduced binding of Tf, decreased iron uptake from Tf, but normal growth on Tf plates. Mutants expressing Tbp2 and not Tbp1 bound less Tf, did not grow on Tf plates, and did not take up iron from Tf. These results suggest that tbpB and tbpA are polycistronic. Tbp2 apparently facilitates binding of Tf but is not essential for acquisition of iron from Tf under these in vitro conditions.
Detailed Scheduling of Tree-like Pipeline Networks with Multiple Refineries
Creators: name: Fattahi, Parviz
Publisher: name: figshare
Year: 2020
Subjects: subject: 90608 Renewable Power and Energy Systems Engineering (excl. Solar Cells)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Detailed Scheduling of Tree-like Pipeline Networks with Multiple Refineries
Identification of Functional Tat Signal Sequences in Mycobacterium tuberculosis Proteins
Creators: name: Rigel, Nathan W.
name: Silverman, Jason S.
name: McDonough, Justin A.
name: McCann, Jessica R.
name: Braunstein, Miriam
name: Tekippe, Erin Mc Elvania
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The twin-arginine translocation (Tat) pathway is a system used by some bacteria to export proteins out from the cytosol to the cell surface or extracellular environment. A functional Tat pathway exists in the important human pathogen Mycobacterium tuberculosis. Identification of the substrates exported by the Tat pathway can help define the role that this pathway plays in the physiology and pathogenesis of M. tuberculosis. Here we used a reporter of Tat export, a truncated β-lactamase, ′BlaC, to experimentally identify M. tuberculosis proteins with functional Tat signal sequences. Of the 13 proteins identified, one lacks the hallmark of a Tat-exported substrate, the twin-arginine dipeptide, and another is not predicted by in silico analysis of the annotated M. tuberculosis genome. Full-length versions of a subset of these proteins were tested to determine if the native proteins are Tat exported. For three proteins, expression in a Δtat mutant of Mycobacterium smegmatis revealed a defect in precursor processing compared to expression in the wild type, indicating Tat export of the full-length proteins. Conversely, two proteins showed no obvious Tat export in M. smegmatis. One of this latter group of proteins was the M. tuberculosis virulence factor phospholipase C (PlcB). Importantly, when tested in M. tuberculosis a different result was obtained and PlcB was exported in a twin-arginine-dependent manner. This suggests the existence of an M. tuberculosis-specific factor(s) for Tat export of a proven virulence protein. It also emphasizes the importance of domains beyond the Tat signal sequence and bacterium-specific factors in determining if a given protein is Tat exported.
A compactness theorem on Branson's $Q$-curvature equation
Creators: name: Li, Gang
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: Let $(M, g)$ be a closed Riemannian manifold of dimension $5$. Assume that $(M, g)$ is not conformally equivalent to the round sphere. If the scalar curvature $R_g\geq 0$ and the $Q$-curvature $Q_g\geq 0$ on $M$ with $Q_g(p)>0$ for some point $p\in M$, we prove that the set of metrics in the conformal class of $g$ with prescribed constant positive $Q$-curvature is compact in $C^{4, α}$ for any $0
description: Comments are welcome
Fence: Striking Distance by Sarah Rees Brennan, Johanna The Mad, C.S. Pacat on Ipad
Creators: name: Serrano
Publisher: name: Zenodo
Year: 2024

description: Fence: Striking Distance by Sarah Rees Brennan, Johanna The Mad, C.S. Pacat

 

 

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Fence: Striking Distance

Sarah Rees Brennan, Johanna The Mad, C.S. Pacat

Page: 368

Format: pdf, ePub, mobi, fb2

ISBN: 9780316456678

Publisher: Little, Brown Books for Young Readers

 

Download pdf files free books Fence: Striking Distance 9780316456678 by Sarah Rees Brennan, Johanna The Mad, C.S. Pacat

Overview

The boys of Kings Row bout with drama, rivalry, and romance in this original YA novel by The New York Times bestselling author Sarah Rees Brennan — inspired by the award-nominated comic series by C.S. Pacat and Johanna The Mad. Sixteen-year-old Nicholas Cox is the illegitimate son of a retired fencing champion who dreams of getting the proper training he could never afford. After earning a place on the elite Kings Row fencing team, Nicholas must prove himself to his rival, Seiji Katayma, and navigate the clashes, friendships, and relationships between his teammates on the road to state championships — where Nicholas might finally have the chance to spar with his golden-boy half-brother. Coach Williams decides to take advantage of the boys' morale after a recent victory and assigns them a course of team building exercises to further deepen their bonds. It takes a shoplifting scandal, a couple of moonlit forest strolls, several hilariously bad dates, and a whole lot of introspection for the team to realize they are stronger together than they could ever be apart. The first installment of this enticing original YA novel series by Sarah Rees Brennan, rich with casual diversity and queer self-discovery, explores never-before-seen drama inspired by C.S. Pacat's critically acclaimed Fence comic series and boasts original cover and interior art by Johanna The Mad. Text and Illustration copyright: © 2020 BOOM! Studios Fence(TM) and © 2020 C.S. Pacat
Activation of the Pseudomonas aeruginosa AlgU Regulon through mucA Mutation Inhibits Cyclic AMP/Vfr Signaling
Creators: name: Jones, Adriana K.
name: Schurr, Michael J.
name: Fulcher, Nanette B.
name: Yahr, Timothy L.
name: Pritchett, Christopher L.
name: Urbanowski, Mark L.
name: Balzer, Grant J.
name: Wolfgang, Matthew C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Pseudomonas aeruginosa is an opportunistic pathogen that causes acute, invasive infections in immunocompromised individuals and chronic, persistent respiratory infections in individuals with cystic fibrosis (CF). The differential progression of acute or chronic infections involves the production of distinct sets of virulence factors. P. aeruginosa strains isolated from patients with acute respiratory infection are generally nonencapsulated and express a variety of invasive virulence factors, including flagella, the type III secretion system (T3SS), type IV pili (TFP), and multiple secreted toxins and degradative enzymes. Strains isolated from chronically infected CF patients, however, typically lack expression of invasive virulence factors and have a mucoid phenotype due to the production of an alginate capsule. The mucoid phenotype results from loss-of-function mutations in mucA, which encodes an anti-sigma factor that normally prevents alginate synthesis. Here, we report that the cyclic AMP/Vfr-dependent signaling (CVS) pathway is defective in mucA mutants and that the defect occurs at the level of vfr expression. The CVS pathway regulates the expression of multiple invasive virulence factors, including T3SS, exotoxin A, protease IV, and TFP. We further demonstrate that mucA-dependent CVS inhibition involves the alternative sigma factor AlgU (AlgT) and the response regulator AlgR but does not depend on alginate production. Our findings show that a single naturally occurring mutation leads to inverse regulation of virulence factors involved in acute and persistent infections. These results suggest that mucoid conversion and inhibition of invasive virulence determinants may both confer a selective advantage to mucA mutant strains of P. aeruginosa in the CF lung.
Effects of environmental lead on the blood proteome of sparrows in Broken Hill
Creators: name: Ali, Zeshan
Publisher: name: Macquarie University
Year: 2023
Subjects: Other education not elsewhere classified

description: Lead (Pb) is a global environmental pollutant, responsible for millions of deaths each year. Elevated lead levels in Australian mining towns, such as Broken Hill and Mount Isa, are severe hazards to human and wildlife health. Living organisms, including animals, have the ability to evolve to resist the negative effects imposed by the environmental stressors like lead. Sparrows are well known for their invasions and adaptations to new environments, including polluted environments. One such example includes the establishment of sparrow populations in lead polluted towns of Broken Hill and Mount Isa in Australia. We hypothesized that lead toxicity induces stress adaptive response in sparrows by regulating the avian proteome to withstand the high lead levels in these towns. To test this hypothesis, we optimized protocols for shotgun proteomics analysis of avian serum and frozen blood. Optimized protocols were then used for shotgun proteomics analysis of serum, frozen whole blood, and blood pellets of sparrows from Broken Hill. By comparing the blood proteome of sparrows with high and low blood lead levels, we identified 13 differentially expressed proteins. At least six proteins, including ferritin, DNA lyase and ribosomal proteins, can be linked to traits related to lead and other heavy metal adaptation.
Least-Squares Linear Dilation-Erosion Regressor Trained using a Convex-Concave Procedure
Creators: name: Oliveira, Angelica Lourenço
name: Valle, Marcos Eduardo
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Optimization and Control (math.OC)
subject: Statistics Theory (math.ST)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: This paper presents a hybrid morphological neural network for regression tasks called linear dilation-erosion regressor ($\ell$-DER). An $\ell$-DER is given by a convex combination of the composition of linear and morphological operators. They yield continuous piecewise linear functions and, thus, are universal approximators. Besides introducing the $\ell$-DER model, we formulate their training as a difference of convex (DC) programming problem. Precisely, an $\ell$-DER is trained by minimizing the least-squares using the convex-concave procedure (CCP). Computational experiments using several regression tasks confirm the efficacy of the proposed regressor, outperforming other hybrid morphological models and state-of-the-art approaches such as the multilayer perceptron network and the radial-basis support vector regressor.
description: 15 pages
CAOS spectroscopy of Am stars Kepler targets
Creators: name: Catanzaro, G.
name: Ripepi, V.
name: Biazzo, K.
name: Busa', I.
name: Frasca, A.
name: Leone, F.
name: Giarrusso, M.
name: Munari, M.
name: Scuderi, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The {\it Kepler} space mission and its {\it K2} extension provide photometric time series data with unprecedented accuracy. These data challenge our current understanding of the metallic-lined A stars (Am stars) for what concerns the onset of pulsations in their atmospheres. It turns out that the predictions of current diffusion models do not agree with observations. To understand this discrepancy, it is of crucial importance to obtain ground-based spectroscopic observations of Am stars in the {\it Kepler} and {\it K2} fields in order to determine the best estimates of the stellar parameters. In this paper, we present a detailed analysis of high-resolution spectroscopic data for seven stars previously classified as Am stars. We determine the effective temperatures, surface gravities, projected rotational velocities, microturbulent velocities and chemical abundances of these stars using spectral synthesis. These spectra were obtained with {\it CAOS}, a new instrument recently installed at the observing station of the Catania Astrophysical Observatory on Mt. Etna. Three stars have already been observed during quarters Q0-Q17, namely: HD\,180347, HD\,181206, and HD\,185658, while HD\,43509 was already observed during {\it K2} C0 campaign. We confirm that HD\,43509 and HD\,180347 are Am stars, while HD 52403, HD\,50766, HD\,58246, HD\,181206 and HD\,185658 are marginal Am stars. By means of non-LTE analysis, we derived oxygen abundances from O{\sc I}$λ$7771--5Å triplet and we also discussed the results obtained with both non-LTE and LTE approaches.
description: accepted in MNRAS main journal 13 pages, 11 figures, 3 tables. arXiv admin note: text overlap with arXiv:1404.0954
Emergence and dimensions of undergraduate-students’ perceptions of themselves as teachers through teaching practice: an exploratory study
Creators: name: FOTOPOULOU, VASILIKI S.
Publisher: name: Educational Journal of the University of Patras UNESCO Chair
Year: 2020
Subjects: Teaching practice, teachers, undergraduate students, exploratory study

description: This paper examines the empirical data of a broader study concerning the views of the undergraduate students of the Department of Educational Science and Early Childhood Education (DESECE) of the University of Patras, Greece (n=144) in regards to how they perceive and describe themselves as teachers during their teaching practice at schools. The paper analyzes the challenges that the students have dealt with, through an experiential approach of the teacher's profession, which appears to influence and shape their perception as teachers. The findings span nine axes and the analysis further indicates that these axes relate with both how closely the undergraduate students perceive themselves as teachers and how the teaching practice itself influences and contributes to how the undergraduate students perceive themselves as teachers.
description: Educational Journal of the University of Patras UNESCO Chair, Vol. 7, N. 2 (2020)
Estimates for the Szegő Projection on Uniformly Finite-Type Subdomains of $\mathbb{C}^2$
Creators: name: Peterson, Aaron
Publisher: name: arXiv
Year: 2015
Subjects: subject: Complex Variables (math.CV)
subject: FOS: Mathematics

description: We prove precise growth and cancellation estimates for the Szegő kernel of an unbounded model domain $Ω\subset\mathbb{C}^2$ under the assumption that ${\rm b}Ω$ satisfies a uniform finite-type hypothesis. Such domains have smooth boundaries which are not algebraic varieties, and therefore admit no global homogeneities that allow one to use compactness arguments in order to obtain results. As an application of our estimates, we prove that the Szegő projection $\mathbb{S}$ of $Ω$ is exactly regular on the non-isotropic Sobolev spaces $NL_k^p({\rm b}Ω)$ for $1
Neurophysiological evidence for remediation of reward processing deficits in chronic pain and opioid misuse following treatment with Mindfulness-Oriented Recovery Enhancement: exploratory ERP findings from a pilot RCT
Creators: name: Froeliger, Brett
name: Garland, Eric L.
name: Howard, Matthew O.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Dysregulated processing of natural rewards may be a central pathogenic process in the etiology and maintenance of prescription opioid misuse and addiction among chronic pain patients. This study examined whether a Mindfulness-Oriented Recovery Enhancement (MORE) intervention could enhance natural reward processing through training in savoring as indicated by event-related brain potentials (ERPs). Participants were chronic pain patients at risk for opioid misuse who were randomized to eight weeks of MORE (n=11) or a support group control condition (n=18). ERPs to images representing naturally rewarding stimuli (e.g., beautiful landscapes, intimate couples) and neutral images were measured before and after 8 weeks of treatment. Analyses focused on the late positive potential (LPP) - an ERP response in the 400 – 1000 ms time window thought to index allocation of attention to emotional information. Treatment with MORE was associated with significant increases in LPP response to natural reward stimuli relative to neutral stimuli which were correlated with enhanced positive affective cue-responses and reductions in opioid craving from pre- to post-treatment. Findings suggest that cognitive training regimens centered on strengthening attention to natural rewards may remediate reward processing deficits underpinning addictive behavior.
Rock Paper Scissors: A Novel by Alice Feeney on Iphone New Format
Creators: name: Stockwell
Publisher: name: Zenodo
Year: 2024

description: Rock Paper Scissors: A Novel by Alice Feeney

 

 

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Rock Paper Scissors: A Novel

Alice Feeney

Page: 320

Format: pdf, ePub, mobi, fb2

ISBN: 9781250266125

Publisher: Flatiron Books

 

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Enrollment and Stopping Rules for Managing Toxicity Requiring Long Follow-Up in Phase II Oncology Trials
Creators: name: Ivanova, Anastasia
name: Song, Guochen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Monitoring of toxicity is often conducted in Phase II trials in oncology to avoid an excessive number of toxicities if the wrong dose is chosen for Phase II. Existing stopping rules for toxicity use information from patients who have already completed follow-up. We describe a stopping rule that uses all available data to determine whether to stop for toxicity or not when follow-up for toxicity is long. We propose an enrollment rule that prescribes the maximum number of patients that may be enrolled at any given point in the trial. Key words: Delayed outcome, Phase II oncology trial, Pocock boundary, Stopping rule, Enrollment rule.
Listening and speaking as powerful literacy practices
Creators: name: MOUSENA, ELENI
Publisher: name: Educational Journal of the University of Patras UNESCO Chair
Year: 2020
Subjects: Listening, speaking, oral communication models, literacy practices

description: The aim of this paper is to establish the significance of listening and speaking as key and powerful components of effective literacy practices. The analysis is based on the Neo-Vygotskian theory, and on the methodology of communication content analysis, and speech monitoring strategies in educational contexts. The nature of oral discourse is analyzed from a functional, an ontogenetic, and a phylogenetic perspective, but also as a tool of symbolic power and knowledge. Τhe paper constitutes a theoretical meta-analysis of the subject. Listening and speaking as active literacy processes are discussed and two major models of oral communication are outlined, the dialogic and the transmission model. Finally, the paper presents research findings on effective literacy practices and formulates conclusions on the value of enhancing strategies that promote listening and speaking in literacy practices.
description: Educational Journal of the University of Patras UNESCO Chair, Vol. 7, N. 2 (2020)
Figure S1 from Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats.
Creators: name: Rafie, Karim
name: Olawale Raimi
name: Ferenbach, Andrew T.
name: Borodkin, Vladimir S.
name: Vaibhav Kapuria
name: Aalten, Daan M. F. Van
Publisher: name: The Royal Society
Year: 2017
Subjects: Biochemistry
Structural Biology

description: O-linked N-acetylglucosamine (O-GlcNAc) is an essential and dynamic post-translational modification found on hundreds of nucleocytoplasmic proteins in metazoa. Although a single enzyme, O-GlcNAc transferase (OGT), generates the entire cytosolic O-GlcNAc proteome, it is not understood how it recognizes its protein substrates, targeting only a fraction of serines/threonines in the metazoan proteome for glycosylation. We describe a trapped complex of human OGT with the C-terminal domain of TAB1, a key innate immunity-signalling O-GlcNAc protein, revealing extensive interactions with the tetratricopeptide repeats of OGT. Confirmed by mutagenesis, this interaction suggests that glycosylation substrate specificity is achieved by recognition of a degenerate sequon in the active site combined with an extended conformation C-terminal of the O-GlcNAc target site.
School leadership in Greece. Autonomy trends and limitations
Creators: name: KATSIGIANNI, ELENI Α.
name: IFANTI, AMALIA A.
Publisher: name: Educational Journal of the University of Patras UNESCO Chair
Year: 2020
Subjects: Role, school principal, Greece, NPM, autonomy

description: This study examines the role of secondary school principal in Greece during the period 1981-2018. The aim is not only to identify the limitations but also to reveal possible autonomy trends that have transformed the Greek school principal’s role. In developing our theoretical perspective, we drew on New Public Management (NPM) and school principal’s role discourse. We then examined the relevant legislative documents following documentary analysis and qualitative content analysis. Our findings firstly support the view that secondary school principal’s role in Greece was transformed to some extent at the legislative level, reflecting this way the impact of NPM practices on the Greek educational policy. Secondly, they show that there might also be some room for school principal’s initiatives that would benefit the students, especially school principal’s participation in teachers’ professional development. Thirdly, the overall legislative initiatives on the Greek school administration, could be considered as a part of its gradual modernization process aiming at devolving authority to the school principal, the teachers’ council and the school board.
description: Educational Journal of the University of Patras UNESCO Chair, Vol. 7, N. 2 (2020)
Are democracies dying one generation at a time?
Creators: name: Wuttke, Alexander
name: Gavras, Konstantin
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: democracy in crisis
subject: democratic deconsolidation
subject: generational change
subject: illiberal democracy
subject: life-cycle effects
subject: populism
subject: preregistration

description: This project contains a template and instructions for registering a research project that uses an existing dataset.
Frost: A Platform for Benchmarking and Exploring Data Matching Results
Creators: name: Graf, Martin
name: Laskowski, Lukas
name: Papsdorf, Florian
name: Sold, Florian
name: Gremmelspacher, Roland
name: Naumann, Felix
name: Panse, Fabian
Publisher: name: arXiv
Year: 2021
Subjects: subject: Databases (cs.DB)
subject: FOS: Computer and information sciences

description: "Bad" data has a direct impact on 88% of companies, with the average company losing 12% of its revenue due to it. Duplicates - multiple but different representations of the same real-world entities - are among the main reasons for poor data quality, so finding and configuring the right deduplication solution is essential. Existing data matching benchmarks focus on the quality of matching results and neglect other important factors, such as business requirements. Additionally, they often do not support the exploration of data matching results. To address this gap between the mere counting of record pairs vs. a comprehensive means to evaluate data matching solutions, we present the Frost platform. It combines existing benchmarks, established quality metrics, cost and effort metrics, and exploration techniques, making it the first platform to allow systematic exploration to understand matching results. Frost is implemented and published in the open-source application Snowman, which includes the visual exploration of matching results.
Academic Race Stereotypes, Academic Self-Concept, and Racial Centrality in African American Youth
Creators: name: Howard, Lionel C.
name: Okeke, Ndidi A.
name: Rowley, Stephanie J.
name: Kurtz-Costes, Beth
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: The relation between academic race stereotype endorsement and academic self-concept was examined in two studies of seventh- and eighth-grade African Americans. Based on expectancy-value theory, the authors hypothesized that academic race stereotype endorsement would be negatively related to self-perceptions. Furthermore, it was anticipated that the relation between stereotype endorsement and self-perceptions would be moderated by racial centrality. The hypothesis was supported in two independent samples. Among students with high racial centrality, endorsement of traditional race stereotypes was linked to lower self-perceptions of academic competence. The stereotype/self-concept relation was nonsignificant among youth for whom race was less central to their identities. These results confirm the supposition of expectancy-value theory and illustrate the interweaving of group and individual identity with motivational beliefs.
A shadow of the repulsive Rutherford scattering in the laboratory frame
Creators: name: Žugec, Petar
name: Rudec, Dario
Publisher: name: arXiv
Year: 2021
Subjects: subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: The paper explores the Rutherford scattering shadow in an entire class of comoving frames -- inertial frames moving along the initial projectile direction -- of which the laboratory frame, where the target is initially at rest, is a representative example. The paper is a continuation of the previous work addressing the scattering shadow in the fixed-target and the center-of-mass frame. It is shown that the transition from these frames is technically quite involved, due to the scattering shadow forming at an infinite distance from an initial target position. The central procedure involves solving the $5^\mathrm{th}$ degree polynomial as a part of an associated extremization procedure. The shadow existence itself is subject to certain conditions, dependent on a given comoving frame. A new and unexpected phenomenon is found within a certain set of comoving frames, including the laboratory frame itself. It consists of a phase transition between an entirely smooth type of shadow and the one characterized by a formation of a sharp edge.
description: 25 pages, 19 figures
Total ionizing dose effects of domestic SiGe HBTs under different dose rate
Creators: name: Mo-Han, Liu
name: Wu, Lu
name: Wu-Ying, Ma
name: Xin, Wang
name: Qi, Guo
name: Cheng-Fa, He
name: Ke, Jiang
name: Xiao-Long, Li
name: Ming-Zhu, Xiong
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The total ionizing radiation (TID) response of commercial NPN silicon germanium hetero-junction bipolar transistors (SiGe HBTs) produced domestic were investigated under the dose rate of 800mGy(Si)/s and 1.3mGy(Si)/s with Co-60 gamma irradiation source, respectively. The changes of the transistor parameter such as Gummel characteristics, excess base current before and after irradiation are investigated. The results of the experiments shows that for the KT1151, the radiation damage have slightly difference under the different dose rate after the prolonged annealing, shows an time dependent effect(TDE). But for the KT9041, the degradations of low dose rate irradiation are more higher than the high dose rate, demonstrate that there have potential enhanced low dose rate sensitive(ELDRS) effect exist on KT9041. The underlying physical mechanisms of the different dose rates response induced by the gamma ray are discussed.