cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Biguanides enhance antifungal activity against Candida glabrata
Creators: name: Shuying Xu
name: Feliu, Marianela
name: K., Allison
name: Lukason, Daniel P.
name: Negoro, Paige E.
name: Khan, Nida S.
name: Dagher, Zeina
name: Feldman, Michael B.
name: Reedy, Jennifer L.
name: Steiger, Samantha N.
name: Tam, Jenny M.
name: Soukas, Alexander A.
name: Sykes, David B.
name: Mansour, Michael K.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: Candida spp. are the fourth leading cause of nosocomial blood stream infections in North America. Candida glabrata is the second most frequently isolated species, and rapid development of antifungal resistance has made treatment a challenge. In this study, we investigate the therapeutic potential of metformin, a biguanide with well-established action for diabetes, as an antifungal agent against C. glabrata. Both wild type and antifungal-resistant isolates of C. glabrata were subjected to biguanide and biguanide-antifungal combination treatment. Metformin, as well as other members of the biguanide family, were found to have antifungal activity against C. glabrata, with MIC50 of 9.34 ± 0.16 mg/mL, 2.09 ± 0.04 mg/mL and 1.87 ± 0.05 mg/mL for metformin, phenformin and buformin, respectively. We demonstrate that biguanides enhance the activity of several antifungal drugs, including voriconazole, fluconazole, and amphotericin, but not micafungin. The biguanide-antifungal combinations allowed for additional antifungal effects, with fraction inhibition concentration indexes ranging from 0.5 to 1. Furthermore, metformin was able to lower antifungal MIC50 in voriconazole and fluconazole-resistant clinical isolates of C. glabrata. We also observed growth reduction of C. glabrata with rapamycin and an FIC of 0.84 ± 0.09 when combined with metformin, suggesting biguanide action in C. glabrata may be related to inhibition of the mTOR complex. We conclude that the biguanide class has direct antifungal therapeutic potential and enhances the activity of select antifungals in the treatment of resistant C. glabrata isolates. These data support the further investigation of biguanides in the combination treatment of serious fungal infections.
Energy Dissipation in the Upper Atmospheres of Trappist-1 Planets
Creators: name: Cohen, O.
name: Glocer, A.
name: Garraffo, C.
name: Drake, J. D.
name: Bell, J. M.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present a method to quantify the upper-limit of the energy transmitted from the intense stellar wind to the upper atmospheres of three of the Trappist-1 planets (e, f, and g). We use a formalism that treats the system as two electromagnetic regions, where the efficiency of the energy transmission between one region (the stellar wind at the planetary orbits) to the other (the planetary ionospheres) depends on the relation between the conductances and impedances of the two regions. Since the energy flux of the stellar wind is very high at these planetary orbits, we find that for the case of high transmission efficiency (when the conductances and impedances are close in magnitude), the energy dissipation in the upper planetary atmospheres is also very large. On average, the Ohmic energy can reach $0.5-1~W/m^2$, about 1\% of the stellar irradiance and 5-15 times the EUV irradiance. Here, using constant values for the ionospheric conductance, we demonstrate that the stellar wind energy could potentially drive large atmospheric heating in terrestrial planets, as well as in hot jupiters. More detailed calculations are needed to assess the ionospheric conductance and to determine more accurately the amount of heating the stellar wind can drive in close-orbit planets.
description: 6 pages, 1 table, 2 figures, accepted to ApJ Letters
Full polar cap cascade scenario: $γ$-ray and X-ray luminosities from spin-powered pulsars
Creators: name: Zhang, Bing
name: Harding, Alice K.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We modify polar cap cascade picture to include the ICS of the higher generation pairs. In such a ``full-cascade'' scenario, not only the perpendicular portion of the energy of the pairs goes to high energy radiation via SR, but the parallel portion of the energy of the pairs can also contribute to high energy emission via ICS with the soft thermal photons from either the full neutron star surface or the hot polar cap. An important output of such a scenario is that the soft tail of the ICS spectrum can naturally result in a non-thermal X-ray component which can contribute to the luminosities observed by ROSAT and ASCA. Here we present an analytic description of such a full polar cap cascade scenario within the framework of Harding & Muslimov acceleration model. We present the theoretical predictions of the $γ$-ray luminosities, the thermal and non-thermal X-ray luminosities for the known spin-powered X-ray pulsars. Our results show that the observed different dependences of the high energy luminosities on the pulsar spin-down luminosities, i.e., $L_γ\propto (L_{\rm sd})^{1/2}$ and $L_x \sim 10^{-3} L_{\rm sd}$, are well reproduced. Our model predicts that the {\em pulsed} soft X-rays in the ROSAT band from most of the millisecond pulsars might be of thermal origin if there is no strong multipole field components near the surfaces of these pulsars.
description: 23 pages, emulateapj style, final version to appear in the Astrophysical Journal
Normal projected entangled pair states generating the same state
Creators: name: Molnar, Andras
name: Garre-Rubio, José
name: Pérez-García, David
name: Schuch, Norbert
name: Cirac, J. Ignacio
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Tensor networks are generated by a set of small rank tensors and define many-body quantum states in a succinct form. The corresponding map is not one-to-one: different sets of tensors may generate the very same state. A fundamental question in the study of tensor networks naturally arises: what is then the relation between those sets? The answer to this question in one dimensional setups has found several applications, like the characterization of local and global symmetries, the classification of phases of matter and unitary evolutions, or the determination of the fixed points of renormalization procedures. Here we answer this question for projected entangled-pair states (PEPS) in any dimension and lattice geometry, as long as the tensors generating the states are normal, which constitute an important and generic class.
Stochastic first passage time accelerated with CUDA
Creators: name: Pierro, Vincenzo
name: Troiano, Luigi
name: Mejuto, Elena
name: Filatrella, Giovannni
Publisher: name: arXiv
Year: 2018
Subjects: subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The numerical integration of stochastic trajectories to estimate the time to pass a threshold is an interesting physical quantity, for instance in Josephson junctions and atomic force microscopy, where the full trajectory is not accessible. We propose an algorithm suitable for efficient implementation on graphical processing unit in CUDA environment. The proposed approach for well balanced loads achieves almost perfect scaling with the number of available threads and processors, and allows an acceleration of about 400x with a GPU GTX980 respect to standard multicore CPU. This method allows with off the shell GPU to challenge problems that are otherwise prohibitive, as thermal activation in slowly tilted potentials. In particular, we demonstrate that it is possible to simulate the switching currents distributions of Josephson junctions in the timescale of actual experiments.
description: 11 pages, 11 figures
Beef cattle in agroforestry system
Creators: name: ANNA VARGA
name: JÓZSEF MOZSGAI (MOZSI MAJOR)
name: ANDREA VITYI
name: ROBERT BOREK
Publisher: name: Zenodo
Year: 2018
Subjects: Diversification; sustainable
tree
alternative feeding resources
limousine
extensive livestock keeping
Hungary
Poland
AFINET
factsheet

description: L'une des difficultés rencontrées pour maintenir durablement le bétail dans les prairies est de fournir une alimentation appropriée aux animaux tout au long de l'année. À la fin de la saison de croissance des pâturages, la valeur nutritive de l'herbe est faible en raison de la sécheresse estivale. Dans les conditions climatiques actuelles, le risque de conditions météorologiques imprévisibles et défavorables augmente. De plus, les pâturages montagneux ouverts qui ne protègent pas du froid et du vent augmentent le stress des animaux, ce qui impacte négativement leur appétit, et renforcent le risque d'érosion des sols. Ces effets négatifs peuvent être évités en plantant des arbres ou en utilisant des zones boisées existantes. Les glands, les fruits sauvages (pommes, poires), les herbes ou le feuillage contribuent à la diversité de l'alimentation et donc au bien-être des animaux. En outre, les arbres créent des lieux de nidification pour les oiseaux qui, selon les agriculteurs, réduisent les nuisances et la nocivité des mouches pour les animaux. Tous ces éléments favorisent la création d'un bétail sain et de bonne qualité.
Scattering off an SO(10) cosmic string
Creators: name: DAVIS, Anne-Christine
name: JEANNEROT, Rachel
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The scattering of fermions from the abelian string arising during the phase transition $SO(10) \rightarrow SU(5) \times Z_2$ induced by the Higgs in the 126 representation is studied. Elastic cross-sections and baryon number violating cross-sections due to the coupling to gauge fields in the core of the string are computed by both a first quantised method and a perturbative second quantised method. The elastic cross-sections are found to be Aharonov-Bohm type. However, there is a marked asymmetry between the scattering cross-sections for left and right handed fields. The catalysis cross-sections are small, depending on the grand unified scale. If cosmic strings were observed our results could help tie down the underlying gauge group.
description: 20 pages
Policy Brief
Creators: name: Stavridi, Vana
name: Kavouras, Panagiotis
name: Konach, Teodora
Publisher: name: Zenodo
Year: 2022

description: This document contains a concise summary of the outcomes ofthe of ROSiE project and recommendations on the best policyoption for responsible Open Science. It is aimed at institutionaland government policymakers, and others interested informulating or influencing policy.
The mixed lineage leukemia 4 (MLL4) methyltransferase complex is involved in transforming growth factor beta (TGF-β)-activated gene transcription
Creators: name: Baas, Roy
name: Teeffelen, Hetty A. A. M. Van
name: Tjalsma, Sjoerd J. D.
name: H. Th. Marc Timmers
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Sma and Mad related (SMAD)-mediated Transforming Growth Factor β (TGF-β) and Bone Morphogenetic Protein (BMP) signaling is required for various cellular processes. The activated heterotrimeric SMAD protein complexes associate with nuclear proteins such as the histone acetyltransferases p300, PCAF and the Mixed Lineage Leukemia 4 (MLL4) subunit Pax Transactivation domain-Interacting Protein (PTIP) to regulate gene transcription. We investigated the functional role of PTIP and PTIP Interacting protein 1 (PA1) in relation to TGF-β-activated SMAD signaling. We immunoprecipitated PTIP and PA1 with all SMAD family members to identify the TGF-β and not BMP-specific SMADs as interacting proteins. Gene silencing experiments of MLL4 and the subunits PA1 and PTIP confirm TGF-β-specific genes to be regulated by the MLL4 complex, which links TGF-β signaling to transcription regulation by the MLL4 methyltransferase complex.
Sensory Landscapes
Creators: name: Van Der Elst, Judith
name: Richards-Rissetto, Heather
name: Díaz-Kommonen, Lily
Publisher: name: Landscape Review
Year: 2018

description: Landscape design needs a novel value system centred on human experience of the landscape rather than simply on economic value. Design-oriented research allows us to shift the focus from mechanistic paradigms towards new sense-making approaches that value both the sensual and the cognitive in human experience. To move in this direction, we investigate cultural and natural aspects of sensory experience in rural landscapes, arguing that: (1) rural (non-urban) regions offer diverse sensory experiences for optimising human health; and (2) spatial interconnectedness between rural and urban areas means that healthy rural regions are critical for urban development. Our key argument is that many rural landscapes contain intrinsically valuable traditional practices that create multisensory experiences with untapped benefits for human wellbeing, particularly in the auditory and olfactory realms, and thus a mapping system that accounts for sensory experience is required.
description: Landscape Review, Vol 18 No 1 (2018): A Time for Designing
Energy-based operator splitting approach for the time discretization of coupled systems of partial and ordinary differential equations for fluid flows: The Stokes case
Creators: name: Carichino, Lucia
name: Guidoboni, Giovanna
name: Szopos, Marcela
Publisher: name: arXiv
Year: 2018
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65M99, 76D99, 76Z99

description: The goal of this work is to develop a novel splitting approach for the numerical solution of multiscale problems involving the coupling between Stokes equations and ODE systems, as often encountered in blood flow modeling applications. The proposed algorithm is based on a semi-discretization in time based on operator splitting, whose design is guided by the rationale of ensuring that the physical energy balance is maintained at the discrete level. As a result, unconditional stability with respect to the time step choice is ensured by the implicit treatment of interface conditions within the Stokes substeps, whereas the coupling between Stokes and ODE substeps is enforced via appropriate initial conditions for each substep. Notably, unconditional stability is attained without the need of subiterating between Stokes and ODE substeps. Stability and convergence properties of the proposed algorithm are tested on three specific examples for which analytical solutions are derived.
Vineyards associated with trees as living support
Creators: name: CLAUDIA CONSALVO
name: JOANA AMARAL PAULO
name: ANDREA PISANELLI
Publisher: name: Zenodo
Year: 2019
Subjects: Vineyards
traditional agroforestry systems
pollarding
AFINET
factsheet

description: En Italie et au Portugal, ainsi que dans de nombreux pays européens, il existe plusieurs exemples de pratiques agroforestières traditionnelles. Ces pratiques étaient courantes dans de nombreuses zones rurales jusqu'à l'introduction de l'agriculture intensive. Actuellement, de tels systèmes peuvent jouer un rôle d'exemple dans l'évolution historique de l'agriculture car leur présence est limitée en raison de la forte demande de maind'oeuvre, de la difficulté à mécaniser et de la production limitée par rapport aux vignobles classiques. En Italie, historiquement, les systèmes agroforestiers les plus importants associaient oliviers (Olea europea L.), céréales ou pâturages, et vignes (Vitis vinifera L.) montant sur des arbres. Ce système était également fréquent dans les régionsdu centre etdu norddu Portugal.Dans ces régions, différentes espèces d'arbres telles que les peupliers (Populus spp.), les érables (Acer spp.) et lesmûriers (Morus spp.) étaient utilisés comme tuteurs, en fonction des conditions pédoclimatiques du site et des objectifs de gestion de la ferme.
Detection of new emission components in PSR B0329+-54
Creators: name: Gangadhara, R. T.
name: Gupta, Y.
name: Lorimer, D. R.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: To study the structure of emission beam, we have analysed the single pulse data of PSR B0329+-54 at 325 and 606 MHz. In order to unambiguously detect the weak emission components, we have developed a new data analysis technique, which we term ``window-thresholding''. By applying this technique to the data, we have detected three new emission components, and also confirmed the presence of a component which was proposed earlier. Hence our analysis indicates that PSR B0329+-54 has nine components, which is among the highest of all the known pulsars. The symmetric distribution of pulse components about the pulse centre, indicates that the emission beam is conal.
description: 2 pages, 1 Postscript figures, uses newpasp.sty
An automorphic generalization of the Hermite-Minkowski theorem
Creators: name: Chenevier, Gaëtan
Publisher: name: arXiv
Year: 2018
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11R, 11F, 11M, 14G

description: We show that for any integer $N$, there are only finitely many cuspidal algebraic automorphic representations of ${\rm GL}_n$ over $\mathbb{Q}$, with $n$ varying, whose conductor is $N$ and whose weights are in the interval $\{0,1,...,23\}$. More generally, we define a simple sequence $(r(w))_{w \geq 0}$ such that for any integer $w$, any number field $E$ whose root-discriminant is less than $r(w)$, and any ideal $N$ in the ring of integers of $E$, there are only finitely many cuspidal algebraic automorphic representations of general linear groups over $E$ whose conductor is $N$ and whose weights are in the interval $\{0,1,...,w\}$. Assuming a version of GRH, we also show that we may replace $r(w)$ with $8 πe^{γ-H_w}$ in this statement, where $γ$ is Euler's constant and $H_w$ the $w$-th harmonic number. The proofs are based on some new positivity properties of certain real quadratic forms which occur in the study of the Weil explicit formula for Rankin-Selberg $L$-functions. Both the effectiveness and the optimality of the methods are discussed.
description: 30 pages, 1 table
Additional file 1 of Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis
Creators: name: Qi, Wenchuan
name: Li, Xiang
name: Ren, Yanrong
name: Liu, Xueying
name: Fu, Hongjuan
name: Wang, Xiao
name: Li, Xiao
name: Xiong, Jian
name: Zheng, Qianhua
name: Cai, Dingjun
name: Liang, Fanrong
Publisher: name: figshare
Year: 2022
Subjects: Biophysics
Biochemistry
Medicine
Molecular Biology
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Marine Biology
Cancer

description: Additional file 1: Figure S1. Uncropped image of blots and gels in the article. Table S1. RT-qPCR primers and siRNA oligonucleotides used in this study.
Supplementary Materials from Functional divergence of bitter taste receptors in a nectar-feeding bird
Creators: name: Wang, Yi
name: Jiao, Hengwu
name: Jiang, Peihua
name: Zhao, Huabin
Publisher: name: The Royal Society
Year: 2019

description: This supplementary file includes: Supplementary Methods, Tables S1-S4, Data Set S1, and Figures S1-S4
Strong enhancement of the Edelstein effect in f-electron systems
Creators: name: Peters, Robert
name: Yanase, Youichi
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The Edelstein effect occurring in systems with broken inversion symmetry generates a spin polarization when an electric field is applied, which is most advantageous in spintronics applications. Unfortunately, it became apparent that this kind of magnetoelectric effect is very small in semiconductors. We here demonstrate that correlation effects can strongly enhance the magnetoelectric effect. Particularly, we observe a strong enhancement of the Edelstein effect in $f$-electron systems close to the coherence temperature, where the $f$-electrons change their character from localized to itinerant. We furthermore show that this enhancement can be explained by a coupling between the conduction electrons and the still localized $f$-electrons.
description: 9 pages, 10 figures
Considerations Concerning the QCD Corrections to $Δρ$
Creators: name: Sirlin, Alberto
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Using recent results of Avdeev et al. and an expansion for $μ_t/\mms$ ($M_t$ is the pole mass and $μ_t\equiv \hat{m_t}(μ_t)$ ), it is shown that when deltarho is expressed in terms of $\hat{m_t}^2(M_t)$, the QCD correction is only $(2-3)\times 10^{-3}$ in the NLO approximation. As a consequence, in terms of $M_t^2$ the correction to $\dr$ is almost entirely contained in $\mmss/M_t^2$, a pure QCD effect. The latter is studied using various optimization procedures, and the results compared with the expansion proposed by Avdeev et al.. Implications for \ew physics are discussed. Threshold effects are analyzed on the basis of a simple sum rule.
description: 11 pages plain LaTeX including 2 tables
O'ZBEK DOSTONCHILIK MAKTABLARI: USTOZ-SHOGIRD AN'ANASI VA IJROCHILIK MADANIYATI
Creators: name: Sherxonova, Mohidil
Publisher: name: Zenodo
Year: 2025

description:  Mazkur maqolada o‘zbek xalqining boy og‘zaki ijodiy merosi – xalq ertaklari, dostonlari, afsona va rivoyatlari, maqol va matallar, topishmoqlar va lirik janrlar keng qamrovda tahlil etilgan. Ayniqsa, dostonchilik san’ati alohida e’tiborga olinib, uning xalqning tarixiy xotirasi, ma’naviy va estetik qarashlarini aks ettirishdagi o‘rni yoritilgan. Maqolada Toshkent, Samarqand, Farg‘ona va boshqa hududlarda shakllangan ilmiy maktablar hamda Qo‘qon, Xorazm, Sherobod, Namangan kabi dostonchilik maktablarining xususiyatlari, yetuk vakillari va ularning ijrochilik an’analari tahlil qilinadi. Shuningdek, bu maktablarning xalq merosini saqlash va yoshlarga yetkazishdagi ahamiyati ko‘rsatib beriladi. Maqola xalq og‘zaki ijodini o‘rganish, uni targ‘ib etish va kelajak avlod qalbida milliy g‘ururni shakllantirishda muhim ilmiy manba sifatida xizmat qiladi.
Design Fieldwork
Creators: name: Milligan, Brett
Publisher: name: Landscape Review
Year: 2018

description: This paper presents a series of design experiments that are used to introduce and prototype a form of research I call design fieldwork. Design fieldwork is a hybrid practice of fieldwork and design intervention in which each informs and is embedded in the other. This method builds knowledge and understanding of landscapes through immersive encounters, actively intervening in the landscape and observing the events and novelty that unfold. In each of the experiments, the designer’s own sensing and affective physical body is foregrounded as a primary medium for exploratory research, either as prelude to design or as the design itself. Two claims are made based on this research. First, the aesthetic and performative experiences of the designer/researcher should be a primary concern in any design research method, as they are pivotal to how sites and landscapes are perceived and constructed, which in turn lead to qualitatively different research outcomes. Second, design fieldwork is positioned as an iterative technique of engaging landscapes that provides unique access to indeterminate formative processes, novelty and serendipity. This embodied exposure to landscapes’ elastic range of becoming can serve as a productive counterpoint to highly conceptual, abstracted and overly determinate design methods in research, teaching and practice.
description: Landscape Review, Vol 18 No 1 (2018): A Time for Designing
The ALFA laser guide star: Operation and Results
Creators: name: Davies, R.
name: Eckart, A.
name: Hackenberg, W.
name: Ott, T.
name: Butler, D.
name: Kasper, M.
name: Quirrenbach, A.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The importance of laser guide stars to the practical usefulness of adaptive optics cannot be understated, and yet there are very few working systems. This contribution discusses the current status of the ALFA laser guide star, with regard to the particular difficulties encountered while observing as well as both the expected performance and that so far achieved from scientific observations. A description is given of a number of experiments involving ALFA which aim to determine the atmospheric turbulence and sodium layer charateristics, and demonstrate the possibility for tilt recovery from laser guide stars.
description: Experimental Astronomy (special edition on ALFA), in press
ARCHITECTURAL FORMS AND CONSTRUCTIVE SOLUTIONS OF BUKHARA POOLS
Creators: name: M.Sh.Babaeva PhD student, Bukhara Engineering Technological Institute
Publisher: name: Zenodo
Year: 2024

description: In this article based on the existing works on the topic and the results of the author's personal research, the traditional methods of building artificial water bodies - ponds of Bukhara are considered. The compositional and constructive solutions of pools in urban ensembles and pools in neighborhood centers were considered.

Key words: pool, neighborhood center, Bukhara, stone pool, constructive solution.
Dynamically enhanced static handwriting representation for Parkinson's disease detection
Creators: name: Diaz, Moises
name: Ferrer, Miguel Angel
name: Impedovo, Donato
name: Pirlo, Giuseppe
name: Vessio, Gennaro
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Computer aided diagnosis systems can provide non-invasive, low-cost tools to support clinicians. These systems have the potential to assist the diagnosis and monitoring of neurodegenerative disorders, in particular Parkinson's disease (PD). Handwriting plays a special role in the context of PD assessment. In this paper, the discriminating power of "dynamically enhanced" static images of handwriting is investigated. The enhanced images are synthetically generated by exploiting simultaneously the static and dynamic properties of handwriting. Specifically, we propose a static representation that embeds dynamic information based on: (i) drawing the points of the samples, instead of linking them, so as to retain temporal/velocity information; and (ii) adding pen-ups for the same purpose. To evaluate the effectiveness of the new handwriting representation, a fair comparison between this approach and state-of-the-art methods based on static and dynamic handwriting is conducted on the same dataset, i.e. PaHaW. The classification workflow employs transfer learning to extract meaningful features from multiple representations of the input data. An ensemble of different classifiers is used to achieve the final predictions. Dynamically enhanced static handwriting is able to outperform the results obtained by using static and dynamic handwriting separately.
Scale invariance with fundamental matters and anomaly: A holographic description
Creators: name: Banerjee, Avik
name: Kundu, Arnab
name: Ray, Augniva
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Generally, quantum field theories can be thought as deformations away from conformal field theories. In this article, with a simple bottom up model assumed to possess a holographic description, we study a putative large N quantum field theory with large and arbitrary number of adjoint and fundamental degrees of freedom and a non-vanishing chiral anomaly, in the presence of an external magnetic field and with a non-vanishing density. Motivated by the richness of quantum chromodynamics under similar condition, we explore the solution space to find an infinite class of scale-invariant, but not conformal, field theories that may play a pivotal role in defining the corresponding physics. In particular, we find two classes of geometries: Schrodinger isometric and warped AdS_3 geometries with an SL(2,R) X U(1) isometry. We find hints of spontaneous breaking of translational symmetry, at low temperatures, around the warped backgrounds.
description: 29 pages , 1 figure
title: ADCO, Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Cart. 173 (11 H 939), 226 folios, f. 0394
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0394, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0394, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
The ALFA Laser and Analysis Tools
Creators: name: Rabien, S.
name: Ott, T.
name: Hackenberg, W.
name: Eckart, A.
name: Davies, R.
name: Kasper, M.
name: Quirrenbach, A.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The optimal performance of adaptive optics systems can only be maintained if the wavefront reference is bright and compact. Experience has shown that both of these important criteria are remarkably difficult to achieve with laser guide stars, and this contribution gives an account of the methods by which ALFA attempts to reach them. First, the production of a high quality, high power laser beam is described. However, this quality is unavoidably compromised along the path to the launch telescope. In order to rectify this, a new set of diagnostic tools which monitor the quality of the out-going beam has been installed, and these are also described. Lastly, we outline a number of possible modifications on which we are working. If successful, these may allow a substantial improvement in the beam quality.
description: Experimental Astronomy (special edition about ALFA), in press. A version with full resolution images can be obtained from the ALFA webpages at http://www.mpia-hd.mpg.de/ALFA/
The Human Body as a Sensory Design Tool to Advance Understanding of Coastal Landscapes Changes
Creators: name: Wingren, Carola
Publisher: name: Landscape Review
Year: 2018

description: As the world’s climate changes and becomes warmer, the sea level is rising and affects the coasts globally (Church et al, 2013). One area where its impact is especially evident is southern Sweden, where land uplift is almost absent and where commitment and preparedness among authorities to adapt to these rising sea levels are limited. In a search for complementary strategies to enhance the work for climate adaptation, alternative methods have been tested in collaborative work with a choreographer and groups of Master’s students in landscape design, where the students used their bodies to express landscape dynamics, principles for protection or interaction with the sea and their own understanding of a future changed meaning and identity within the coastal landscape. In one of the choreographed, design-driven movement workshops, the students walked the high-water line as it appears on maps and, with other movements, they integrated the dynamics of the sea and its confrontation with coastal life. The challenging and tentative work, conceptualised as ‘reflective motion’, ended in a public performance where the students identified and dramatised threats, reconciliation and possibilities for change in relation to future sea-level rise on the site. The performance took place along a 2-kilometre stretch and concluded with a public discussion in the library. The method seemed to be useful and complementary to other methods; by ‘blurring’ the static high-water line in favour of a more complex understanding; by being an interactive tool between the researcher, the designer, the choreographer and a coastal society (Germundsson and Wingren, 2017); by developing a ‘value action’ or a common language of environmental awareness (Hirsch, 2016); and by giving space for emotional expressions and mourning related to loss of landscapes, landscape identity and meaning (Cunsolo Willox, 2012). The results indicate that ‘reflective motion’ is a method that can be investigated further as a platform for better-informed design and as a forum where local people and authorities can meet to share their landscape knowledge.
description: Landscape Review, Vol 18 No 1 (2018): A Time for Designing
Modeling lithium rich carbon stars in the Large Magellanic Cloud: an independent distance indicator ?
Creators: name: Ventura, P.
name: D'Antona, F.
name: Mazzitelli, I.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the first quantitative results explaining the presence in the Large Magellanic Cloud of some asymptotic giant branch stars that share the properties of lithium rich carbon stars. A self-consistent description of time-dependent mixing, overshooting, and nuclear burning was required. We identify a narrow range of masses and luminosities for this peculiar stars. Comparison of these models with the luminosities of the few Li-rich C stars in the Large Magellanic Cloud provides an independent distance indicator for the LMC
description: 7 pages, 2 figures
The complex world of plant protease inhibitors: Insights into a Kunitz-type cysteine protease inhibitor of Arabidopsis thaliana
Creators: name: Rustgi, Sachin
name: Boex-Fontvieille, Edouard
name: Reinbothe, Christiane
name: Diter Von Wettstein
name: Reinbothe, Steffen
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Plant Biology
subject: FOS: Biological sciences

description: Plants have evolved an intricate regulatory network of proteases and corresponding protease inhibitors (PI), which operate in various biological pathways and serve diverse spatiotemporal functions during the sedentary life of a plant. Intricacy of the regulatory network can be anticipated from the observation that, depending on the developmental stage and environmental cue(s), either a single PI or multiple PIs regulate the activity of a given protease. On the other hand, the same PI often interacts with different targets at different places, necessitating another level of fine control to be added in planta. Here, it is reported on how the activity of a papain-like cysteine protease dubbed RD21 (RESPONSIVE TO DESICCATION 21) is differentially regulated by serpin and Kunitz PIs over plant development and how this mechanism contributes to defenses against herbivorous arthropods and microbial pests.
Supplementary Materials from Functional divergence of bitter taste receptors in a nectar-feeding bird.
Creators: name: Wang, Yi
name: Jiao, Hengwu
name: Jiang, Peihua
name: Zhao, Huabin
Publisher: name: The Royal Society
Year: 2019

description: This supplementary file includes: Supplementary Methods, Tables S1-S4, Data Set S1, and Figures S1-S4
Understanding Soft-Tissue Behavior for Application to Microlaparoscopic Surface Scan
Creators: name: Erden, M.
name: Rosa, B.
name: Szewczyk, J.
name: Morel, G.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Robotics (cs.RO)
subject: Medical Physics (physics.med-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: This paper presents an approach for understanding the soft tissue behavior in surface contact with a probe scanning the tissue. The application domain is confocal microlaparoscopy, mostly used for imaging the outer surface of the organs in the abdominal cavity. The probe is swept over the tissue to collect sequential images to obtain a large field of view with mosaicking. The problem we address is that the tissue also moves with the probe due to its softness; therefore the resulting mosaic is not in the same shape and dimension as traversed by the probe. Our approach is inspired by the finger slip studies and adapts the idea of load-slip phenomenon that explains the movement of the soft part of the finger when dragged on a hard surface. We propose the concept of loading-distance and perform measurements on beef liver and chicken breast tissues. We propose a protocol to determine the loading-distance prior to an automated scan and introduce an approach to compensate the tissue movement in raster scans. Our implementation and experiments show that we can have an image-mosaic of the tissue surface in a desired rectangular shape with this approach.
Iris cultivation in traditional olive groves
Creators: name: CLAUDIA CONSALVO
name: ANDREA PISANELLI
Publisher: name: Zenodo
Year: 2019
Subjects: Medicinal plants
agroforestry
olive groves
silvoarable systems
Iris
AFINET
factsheet

description: L'Italie importe lamajorité des plantesmédicinales de pays d'Europe orientale, d'Extrême-Orient et d'Amérique latine. Pour cette raison, la culture de plantes médicinales est particulièrement intéressante et novatrice. En Europe, la France est le pays de référence pour ce type de production, tandis qu'en Italie, la culture des herbes médicinales a toujours été reléguée dans des zones marginales, car les zones planes sont exploitées pour des cultures plus rentables. La culture de plantes médicinales en Italie est souvent pratiquée dans les zones montagneuses, ou ne convenant pas à d'autres cultures. L'iris est connue et appréciée depuis l'Antiquité pour les propriétés de ses rhizomes séchés. L'iris est utilisée depuis des siècles dans les secteursmédical et cosmétique : comme remède contre la toux, les morsures de serpent et la dépression, pour les parfums, les poudres, les savons et les pigments.
title: Leading in times of crisis and remote work: perceived consideration leadership behavior and its effect on follower work engagement
Creators: name: Sedefoglu, Didem
name: Ohly, Sandra
name: Schmitt, Antje
name: Göritz, Anja Simone
Publisher: name: Universität Kassel
Year: 2024
Subjects: subject: COVID-19
subject: crisis
subject: work engagement
subject: optimism
subject: remote work
subject: consideration
subject: leadership
subject: pandemic
subject: 300
subject: 330
subject: COVID-19
subject: Krise
subject: Arbeitsmotivation
subject: Optimismus
subject: Telearbeit
subject: Rücksicht
subject: Führungskraft

description: Gefördert durch den Publikationsfonds der Universität Kassel
The ALFA Laser: Beam Relay and Control System
Creators: name: Ott, T.
name: Hackenberg, W.
name: Rabien, S.
name: Eckart, A.
name: Hippler, S.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The ALFA laser subsystem uses a 4 watt continuous wave laser beam to produce an artificial guide star in the mesospheric sodium layer as a reference for wavefront sensing. In this article we describe the system design, focusing on the layout of the beam relay system. It consists of seven mirrors, four of which are motor-controlled in closed loop operation accounting for turbulences inside the dome and flexure of the main telescope. The control system features several computers which are located close to analysis and control units. The distribution of the tasks and their interaction is presented, as well as the graphical user interface used to operate the complete system. This is followed by a discussion of the aircraft detection system ALIENS. This system shuts off the laser beam when an object passes close to the outgoing laser.
description: Experimental Astronomy (special issue about ALFA), accepted
Urban Comfort in a Future Compact City: Analysis of Open-space Qualities in the Rebuilt Christchurch Central City
Creators: name: Tavares, Silvia
name: Swaffield, Simon
Publisher: name: Landscape Review
Year: 2017

description: The increase in urban population has required cities to rethink their strategies for minimising greenhouse gas impacts and adapting to climate change. While urban design and planning policy have been guided by principles such as walkability (to reduce the dependence on cars) and green infrastructure (to enhance the quality of open spaces to support conservation and human values), there have been conflicting views on what spatial strategies will best prepare cities for a challenging future. Researchers supporting compact cities based upon public Transit Oriented Development have claimed that walkability, higher density and mixed-uses make cities more sustainable (Owen, 2009) and that, while green spaces in cities are necessary, they are dull in comparison with shopfronts and street vendors (Speck, 2012, p 250). Other researchers claim that green infrastructure is fundamental to improving urban sustainability and attracting public space users with improved urban comfort, consequently encouraging walkability (Pitman and Ely, 2013). Landscape architects tend to assume that ‘the greener the better’; however, the efficiency of urban greenery in relation to urban comfort and urbanity depends on its density, distribution and the services provided. Green infrastructure can take many forms (from urban forests to street trees) and provide varied services (amended microclimate, aesthetics, ecology and so forth). In this paper, we evaluate the relevance of current policy in Christchurch regarding both best practice in green infrastructure and urban comfort (Tavares, 2015). We focus on the Christchurch Blueprint for rebuilding the central city, and critically examine the post-earthquake paths the city is following regarding its green and grey infrastructures and the resulting urban environment. We discuss the performance and appropriateness of the current Blueprint in post-earthquake Christchurch, particularly as it relates to the challenges that climate change is creating for cities worldwide.
description: Landscape Review, Vol 17 No 2 (2017): Integrated Urban Grey and Green Infrastructures
Additional file 1 of Study on the relationship between hormone and Lp(a) in Chinese overweight/obese patients
Creators: name: Chang, Xiaona
name: Bian, Nannan
name: Ding, Xiaoyu
name: Li, Jinman
name: An, Yu
name: Wang, Jiaxuan
name: Liu, Jia
name: Wang, Guang
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Additional file 1 Supplemental Table 1. Characteristics of male participants with various levels of Lp(a). Supplemental Table 2. Characteristics of female participants with various levels of Lp(a). Supplemental Table 3. Multiple linear regression between Lp(a) levels and other parameters in male participants. Supplemental Table 4. Multiple linear regression between Lp(a) levels and other parameters in female participants.
Effective Field Theory Approach to Parton-Hadron Conversion in High Energy QCD Processes
Creators: name: Geiger, K.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A QCD based effective action is constructed to describe the dynamics of confinement and symmetry breaking in the process of parton-hadron conversion. The deconfined quark and gluon degrees of freedom of the perturbative QCD vacuum are coupled to color singlet collective fields representing the non-perturbative vacuum with broken scale and chiral symmetry. The effective action recovers QCD with its scale and chiral symmetry properties at short space-time distances, but yields at large distances (r > 1 fm) to the formation of symmetry breaking gluon and quark condensates. The approach is applied to the evolution of a fragmenting $q\bar q$ pair with its generated gluon distribution, starting from a large hard scale $Q^2$. The modification of the gluon distribution arising from the coupling to the non-perturbative collective field results eventually in a complete condensation of gluons. Color flux tube configurations of the gluons in between the $q\bar q$ pair are obtained as solutions of the equations of motion. With reasonable parameter choice, the associated energy per unit length (string tension) comes out $\simeq 1$ GeV/fm, consistent with common estimates.
description: CERN-TH. 7440/94, 34 pages, 10 figures, Latex file plus figures encoded with uufiles