cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Bildungsangebote für ältere Menschen
Creators: name: Kolland, Franz
Publisher: name: bildungsforschung
Year: 2010

description: Demographische Veränderungen und die Durchsetzung der Wissensgesellschaft rücken im Feld des lebenslangen Lernens zunehmend die Altersbildung in den Vordergrund. Nach einer einleitenden Diskussion der fachwissenschaftlichen Begriffsauseinandersetzung wird in der Folge anhand einer empirischen Untersuchung in Österreich, die Begriffsdiskussion aus der Sicht der Praktiker in der Altersbildung fortgeführt. Weiters werden auf Basis dieser Untersuchung Bildungsangebote für ältere Menschen aus dem Blickwinkel der Anbieter dargestellt. Befragt wurden sowohl ExpertInnen als auch KursleiterInnen der Bildungsarbeit mit älteren Menschen. Als zentrales Ergebnis konnte eine Vielfalt der Angebote und Anbieter auf einem niedrigen Verbreitungsniveau herausgefunden werden. Mit Bildung im Alter verknüpfen die KursleiterInnen sowohl aufbewahrende Aspekte als auch Aspekte der Wissensvermittlung und Kompetenzen der Alltagsbewältigung.
description: bildungsforschung, Bd. 2 (2006): Bildung Älterer
A new genus and species of polychaete worm (Family Orbiniidae) from methane seeps in the Gulf of Mexico, with a review of the systematics and phylogenetic interrelationships of the genera of Orbiniidae
Creators: name: BLAKE, James A.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2000

description: An abundant polychaete Methanoaricia dendrobranchiata gen. nov. et sp. nov., found in association with
 methane seeps (>500 m) in the Gulf of Mexico, has affiliations with the family Orbiniidae. These seepworms are large, up
 to 15 cm long, 7-9 mm wide anteriorly, with hundreds of crowded segments. Distinct body regions are absent. Branched
 branchiae extend over the entire body. The prostomium is narrow, elongate, directed ventrally, and bluntly rounded on the
 anterior margin. Eyes are absent; eversible nuchal papillae are present. The peristomium is reduced to a single, narrow
 achaetous ring. Parapodia bear long, laterally directed, cirriform noto- and neuropodial lamellae. Capillary chaetae have
 transverse rows of bristles. Narrow, pointed notopodial spines have a single subapical spur or secondary tooth. Neurochaetae
 of anterior chaetigers include a few threadlike capillaries, about 5 simple spines with weakly developed crenulations along
 their margins, and 3-4 emergent curved aciculae; spines are absent by the middle of the body. The pygidium has a terminal
 anus surrounded by several long, tapering cirri. The chaetal and branchial structure of these worms allies them most closely
 to the Orbiniidae despite the lack of distinct body regions. In order to understand the relationship of the seepworm with other
 orbiniid genera, a phylogenetic (cladistic) analysis was performed. The results of this analysis suggests that the current
 classification of orbiniid genera into subfamilies is not appropriate and a new classification is proposed that is based on
 increasing modification of body structure and chaetae. Two clades or subfamilies of Orbiniidae are proposed  using these
 characters rather than the traditional peristomial ring structure. The seepworm appears to be a separate and distinct sister
 taxon.
Quantum erasure in the presence of a thermal bath: the effects of system-environment microscopic correlations
Creators: name: de Magalhães, A. R. Bosco
name: de Faria, J. G. Peixoto
name: Rossi, R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the role of the environment in a quantum erasure setup in the cavity quantum electrodynamics domain. Two slightly different schemes are analyzed. We show that the effects of the environment vary when a scheme is exchanged for another. This can be used to estimate the macroscopic parameters related to the system-environment microscopic correlations.
description: 10 pages, 2 figures
Normal mouse peritoneum contains a large population of Ly-1+ (CD5) B cells that recognize phosphatidyl choline. Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes
Creators: name: Arnold, Larry W.
name: Mercolino, Thomas J.
name: Haughton, Geoffrey
name: Hawkins, Lee A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1988

description: We have found that, in the peritoneums of normal adult mice, 5-15% of lymphocytes bind a fluorescent liposome probe. In ontogeny, cells with this specificity were shown to appear by 8 d after birth, and increase to the adult frequency by 2-3 wk. Some older mice contain an expanded population of these cells. We have shown that liposome binding occurs by cell surface IgM recognizing the common membrane phospholipid, phosphatidyl choline (PtC). Virtually all of these PtC-specific cells bear the cell surface marker Ly-1. Our results indicate that roughly 1 in 10 peritoneal Ly-1+ B cells has this single specificity. We have found that the precursors to all the cells that form plaques on protease-treated autologous erythrocytes (BrMRBC) are included in the PtC-specific population and can be isolated by FACS. We believe this is the first report of sorting large numbers of B cells with a single antigen specificity from normal, unimmunized animals. This method will allow for in vitro and in vivo studies of differentiative and proliferative properties of Ly-1+ B cells, which may help define their role in development and disease.
(3766) Swanston Drysdale
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Das Kopftuch als Herausforderung für den pädagogischen Umgang mit Toleranz. Ein empirisch fundierter Beitrag zur Kopftuch-Debatte [Einzelbeitrag]
Creators: name: Karakasoglu, Yasemin
Publisher: name: bildungsforschung
Year: 2010

description: Das Kopftuch einer Minderheit muslimischer Lehrerinnen hat sich als Katalysator des Diskurses um Migration, Integration und Toleranz entwickelt. Einsichten in die Einstellungen und Lebenswelten von Mädchen und Frauen, die ein Kopftuch tragen, vermitteln einige Studien, allerdings existiert bislang lediglich eine Untersuchung zur Zielgruppe der Lehramtskandidatinnen mit Kopftuch. Der folgende Beitrag präsentiert empirisches Material aus dieser Untersuchung über Einstellungen von jungen Musliminnen mit und ohne Kopftuch zu Toleranz und Integration, das vor der Eröffnung der so genannten ´Kopftuchdebatte´ erhoben wurde. Damit wird Material präsentiert, welches als unverdächtig gelten kann, durch mittlerweile bekannte Argumentationsmuster beeinflusst worden zu sein.
description: bildungsforschung, Bd. 2 (2006): Bildung Älterer
The lpr gene causes an intrinsic T cell abnormality that is required for hyperproliferation
Creators: name: Eisenberg, Robert A.
name: Katagiri, Takuya
name: Cohen, Philip L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1988

description: The lpr gene induces marked lymphoproliferation characterized by the massive accumulation of T cells of an unusual phenotype and concomitant autoimmune disease. To clarify the mechanism of the lpr effect, bone marrow cells from B6-lpr/lpr (Ly-1.2) and B6-+/+ (Ly-1.1) mice were transferred into lethally irradiated B6-lpr/lpr mice. As has been previously reported, recipients of the B6-lpr/lpr bone marrow showed the typical lpr phenotype with marked lymphadenopathy, splenomegaly and increased levels of autoantibodies; while the recipients of B6-+/+ bone marrow had normal sized lymph nodes and spleen and no autoantibodies. A third group of mice received an equal mixture of bone marrow cells from the B6-lpr/lpr and B6-+/+ donors. These mice showed both lymphadenopathy and autoantibody production comparable to that of recipients of the B6-lpr/lpr marrow alone. Immunofluorocytometric analysis of the lymphoid populations in these mixed bone marrow recipients established that the T cells from the lpr/lpr and +/+ donors were equivalently represented in the peripheral blood and thymus. In striking contrast, the T cells that accumulated in abnormally large numbers in the lymph nodes were almost entirely from the lpr donor. Their surface phenotype was Thy-1+(dull), Ly-1.2+(dull), Lyt-2-, L3T4-, 9F3+, and 3A1+, which is consistent with that found in intact lpr mice. These results indicate that the lpr gene causes an intrinsic defect directly within the T cells that accumulate in large numbers in lpr mice. In addition, the presence of the +/+ T cells cannot prevent the expression of the lpr abnormalities.
Neonatal Multisystem Inflammatory Syndrome (MIS-N): A Case Series of Thirteen Neonates
Creators: name: International Clinical and Medical Case Reports Journal
Publisher: name: Salient Visionary Publications LLC
Year: 2023

description: The occurrence of Neonatal Multisystem Inflammatory Syndrome (MIS-N) in the context of maternal SARS-CoV-2 infection is a rare phenomenon. This retrospective study presents an analysis of the clinical manifestations, diagnostic investigations, treatment modalities, and outcomes observed in a cohort of thirteen neonates diagnosed with MIS-N between September 2020 and November 2021. The study draws data from six distinct healthcare facilities in West Bengal, India. Noteworthy findings from this investigation include an absence of gender-based disparity within the neonatal cohort, with four neonates presenting severe disease, three of whom succumbed to the condition. Interestingly, all neonatal fatalities were male, while the sole survivor was female. Among neonates with cardiac involvement, heart failure and shock were common presentations, with a notable absence of coronary artery involvement, a feature occasionally seen in the paediatric age group.
Restricted immunoglobulin variable region gene usage by normal Ly-1 (CD5+) B cells that recognize phosphatidyl choline
Creators: name: Afshari, A.
name: Sasser, D.
name: Haughton, G.
name: Travis, W. W.
name: Arnold, L. W.
name: Mercolino, T. J.
name: Locke, A. L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1989

description: 5-15% of lymphocytes in the peritoneums of normal adult B10.H-2aH- 4bp/Wts (2a4b) mice are CD5+ (Ly-1) B cells that recognize phosphatidyl choline (PtC), a phospholipid component of all mammalian cells. We produced a set of IgM-secreting hybridomas from the peritoneal cells of normal, adult 2a4b mice. We found that this set of hybridomas shows a similarly high frequency of antibodies specific for PtC (21 of 86) that also react with bromelain-treated mouse erythrocytes. Restriction fragment analysis of Ig gene rearrangements and analysis of expressed Ig idiotypes reveal that these cells use a restricted set of variable region genes to generate the PtC-specific antibodies. The Ig genes used by the PtC-specific hybridomas appear to be the same as those found in the PtC-specific Ly-1 B cell lymphomas, CH27 and CH34.
Editorial zum Schwerpunktthema Medien statt „Gedächtnisâ€
Creators: name: Kammerl, Rudolf
name: Schütz, Julia
Publisher: name: bildungsforschung
Year: 2010

description: In diesem Beitrag wird ein kurzer Überblick über die Artikel der Ausgabe 2 (2009) zum Themenschwerpunkt „Medien statt Gedächtnis“ gegeben.
description: bildungsforschung, Bd. 2 (2009): Medien statt Gedächtnis
Medien und Gedächtniskultur aus bildungstheoretischer Perspektive
Creators: name: Hochleitner, Moritz
name: Inan, Alev
name: Pollak, Guido
Publisher: name: bildungsforschung
Year: 2010

description: Ausgehend von Gedächtnistheorien von Maurice Halbwachs und Aleida und Jan Assmann wird aus bildungstheoretischer Perspektive das Verhältnis von Gedächtnis, Bildung und Individuum in der neuen digitalen Wissenswelt untersucht. Grundlegende These des Artikels ist, dass die digitale Speicherung von Inhalten zu einem Wandel in der Verarbeitung von Informationen zu Wissen führt, so dass auch der Bildungsbegriff erneuter Reflexion bedarf.
description: bildungsforschung, Bd. 2 (2009): Medien statt Gedächtnis
(3761) Robert Cargill
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Autoantibodies in chronic graft versus host result from cognate T-B interactions
Creators: name: Cohen, Philip L.
name: Cheek, Robert L.
name: Eisenberg, Robert A.
name: Morris, Suzanne C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1990

description: A chronic graft-versus-host reaction (GVH) induced in nonautoimmune mice causes a syndrome that closely resembles SLE. In this model, donor T cells react against incompatible host Ia structures and generate excessive help, which activates a subpopulation of self-reactive B cells. We have studied whether these self-reactive B cells are activated by direct interaction with alloreactive T cells or by nonspecific bystander effects. Two types of chimeras were made: double- parental chimeras, differing at both Ia and Igh allotype [B6.C20 + bm12- ---(B6.C20 x bm12)F1]; and control chimeras [(B6.C20 x bm12)F1---- (B6.C20 x bm12)F1]. A chronic GVH syndrome was induced in the chimeras by infusion of B6 or bm12 spleen cells. Coombs and antichromatin autoantibodies were measured using Igh allotype-specific immunoassays. The double-parental chimeras that received bm12 cells made autoantibodies principally of the Igha allotype, indicating that the bm12 T cells interacted only with the Iab-bearing host B cells. Conversely, double-parental chimeras that received B6 cells made mostly Ighb autoantibodies, indicating direct cognate interaction with the Iabm12-bearing host B cells. The control chimeras made autoantibodies of both allotypes. These results indicate that autoantibodies in chronic GVH result from direct T-B interactions and not from nonspecific T cell-derived factors.
Autoantibodies specific for different isoforms of CD45 in systemic lupus erythematosus
Creators: name: Jarjour, Wael
name: Mimura, Toshihide
name: Fernsten, Philip
name: Winfieldc, John B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1990

description: Nearly one-third of IgM antilymphocyte autoantibody-positive sera from patients with systemic lupus erythematosus (SLE) contain IgM antibodies to one or more 180-220-kD molecules (p180, p190, p205, and p220) in blots of glycoproteins purified from T cells by wheat germ agglutinin affinity chromatography. Identity of these IgM targets with multiple isoforms of CD45 was established by their specific depletion from T cell glycoproteins by immunoprecipitation with T191, a monoclonal antibody (mAb) that reacts with an epitope common to all CD45 isoforms. Although the anti-CD45 autoantibodies recognize higher molecular weight isoforms primarily, antigenic specificity in this system is quite heterogeneous and includes multiple distinct CD45 isoforms on different types of T cells that are, at least in part, different from those reactive with mAbs 2H4 and UCHL-1. Because CD45 is a major membrane protein tyrosine phosphatase that plays a critical role in antigen- induced T cell activation, the present data may be relevant to some of the antilymphocyte antibody-mediated immunologic abnormalities that characterize SLE and related autoimmune diseases.
P-wave holographic superconductor/insulator phase transitions affected by dark matter sector
Creators: name: Rogatko, Marek
name: Wysokinski, Karol I.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The holographic approach to building the p-wave superconductors results in three different models: the Maxwell-vector, the SU(2) Yang-Mills and the helical. In the probe limit approximation, we analytically examine the properties of the first two models in the theory with {\it dark matter} sector. It turns out that the effect of {\it dark matter} on the Maxwell-vector p-wave model is the same as on the s-wave superconductor studied earlier. For the non-Abelian model we study the phase transitions between p-wave holographic insulator/superconductor and metal/superconductor. Studies of marginally stable modes in the theory under consideration allow us to determine features of p-wave holographic droplet in a constant magnetic field. The dependence of the superconducting transition temperature on the coupling constant $α$ to the {\it dark matter} sector is affected by the {\it dark matter} density $ρ_D$. For $ρ_D>ρ$ the transition temperature is a decreasing function of $α$. The critical chemical potential $μ_c$ for the quantum phase transition between insulator and metal depends on the chemical potential of dark matter $μ_D$ and for $μ_D=0$ is a decreasing function of $α$.
description: 25 pages, 3 figures, JHEP style (included), version accepted for publication in JHEP
(3763) James Rankin
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Gedächtnis und Beweis - Was man von Akten für E-Portfolios lernen kann
Creators: name: Muckel, Petra
name: Vogt, Sebastian
Publisher: name: bildungsforschung
Year: 2010

description: Wir möchten erste Überlegungen zu der Frage, inwiefern E-Portfolios in der Lage sind, an die Stelle einer i.w.S. konventionellen analogen Akte aus Papier zu treten, vorstellen. Dazu werden die Möglichkeiten und Begrenzungen von E-Portfolios diskturiert, personenbezogene Prozesse und Ereignisse für die Nachwelt zu dokumentieren und in ihrer Existenz nachzuweisen, langfristig dadurch vielleicht auch die Akte eines universitären Prüfungsamtes zu ersetzen, im Vergleich mit analogen Akten herausarbeiten.
description: bildungsforschung, Bd. 2 (2009): Medien statt Gedächtnis
An association between a hesionid polychaete and temnopleurid echinoids from Singapore
Creators: name: CHIM, Chee Kong
name: ONG, Joyce Jia Lin
name: TAN, Koh Siang
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2013

description: The hesionid polychaete Oxydromus cf. angustifrons (Fauvel, 1953 non Grube, 1878) occurred on the peristomial membrane and on the test between the aboral spines of two echinoid species Salmacis sphaeroides (L., 1758) and Temnopleurus toreumaticus (Leske, 1778) in Singapore. Each S. sphaeroides was associated with 1–5 polychaetes, whereas almost all T. toreumaticus individuals each carried only one polychaete. There was no linear relationship between host size and the number of polychaetes, although larger echinoids sometimes carried more polychaetes. In echinoids carrying a single polychaete, the polychaete was almost always located on the peristomial membrane (80% in S. sphaeroides and 62% in T. toreumaticus), and sometimes on the test between the aboral spines. In echinoids with multiple polychaetes, the largest individual was always on the peristomial membrane while the smaller ones were on the test between the spines. The polychaetes displayed aggressive territorial behaviour, attacking each other with their proboscis when there was more than one individual on a single echinoid. Laboratory observations also showed that the polychaetes had strong affinity for the peristomial membrane – they returned to the host within 7 minutes if deliberately displaced and individuals remained on the peristomial membrane of living echinoid over a period of more than two weeks. The polychaetes neither caused damage nor provided any benefit to their hosts, suggesting that the association is of commensal nature.
(3765) Frances Thalia How
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Arm regeneration frequencies in Florometra serratissima (Crinoidea, Echinodermata): impact of depth of habitat on rates of arm loss
Creators: name: BAUMILLER, Tomasz K.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2013

description: Today stalked crinoids are restricted to depths greater than 100 m whereas the fossil record indicates that they were diverse and abundant in shallow water through most of their history. Their disappearance from shallow settings started sometime in the mid-Mesozoic, coincident with the Mesozoic Marine Revolution; not surprisingly, predation has been hypothesized as the cause of their displacement and their present-day bathymetric distribution. Implicit in this is that predation pressure on crinoids decreases with depth of habitat. To test this in modern oceans, patterns of arm regeneration in the comatulid crinoid Florometra serratissima A.H. Clark, 1907, collected at depths ranging ~ 80 to over 1100 m were examined. The application of a newly developed method for reconstructing predation pressure, defined here as "the attack frequency experienced by the prey" (Aronson, 1987, p. 187), from patterns of regenerating arms indicates that arm loss rates decrease with depth: shallowest individuals of F. serratissima lose an arm ~ once every two months, while those from the greatest depth lose an arm very infrequently, less than once every two years. Assuming that arm loss is a consequence of interactions with predators and not abiotic factors, rates of arm loss indicate that predation pressure is depth-dependent.
Constitutive expression of a groEL-related protein on the surface of human gamma/delta cells
Creators: name: Mimura, Toshihide
name: Denning, Stephen
name: Mizzen, Lee A.
name: Jarjour, Wael
name: Shaw, Melody
name: Welch, William J.
name: Winfield, John B.
name: Haynes, Barton F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1990

description: Rabbit antibodies to hsp58 (P1), the human homologue of the Escherichia coli stress protein groEL, react specifically in indirect immunofluorescence and complement-dependent microcytoxicity experiments with a cell surface antigen expressed constitutively by T cell lines bearing gamma/delta receptors. This anti-hsp58-reactive antigen is not demonstrable on T cells that express alpha/beta receptors or on various cells that lack T cell receptors. Certain evidence was obtained to suggest that the target antigen on the surface of gamma/delta T cells is a approximately 77-kD protein distinct from intracellular hsp58 and known members of the hsp70 stress protein family. While the exact nature and significance of this anti-hsp58-reactive protein remain to be determined, these data may help to clarify the roles of groEL- related stress proteins and gamma/delta cells that recognize groEL homologous in immunologic defense against infection and in autoimmune disease.
Inhibition of Ly-6A antigen expression prevents T cell activation
Creators: name: Dougherty, Joseph P.
name: Flood, Patrick M.
name: Row, Yacov
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1990

description: Antisense oligonucleotides complementary to the 5' end of the mRNA encoding the Ly-6A protein were used to block the expression of that protein. Using this approach we could inhibit the expression of Ly-6A by 60-80% in antigen-primed lymph node (LN) T cells as well as in the D10 T cell clone. Inhibition of Ly-6 expression resulted in the inability to restimulate in vitro, antigen-primed T cells. It also blocked the activation of normal spleen cells by Con A, monoclonal antibody (mAb) to CD3, and mAb to Ly-6. In contrast, stimulation of normal spleen cells with the pharmacological agents PMA + ionomycin were unaffected by the inhibition of Ly-6 expression. Similar results were obtained with the D10 T cell clone; stimulation with Con A + interleukin 1 (IL-1), antigen-presenting cells (APC), or the clonotypic antibody + IL-1 was greatly reduced in the presence of antisense oligonucleotides to Ly-6. Stimulation with PMA + ionomycin was again unaffected. We also studied the effect of antisense oligonucleotides on stimulation of preactivated D10 cells. Preactivation of D10 cells with Con A + IL-1 renders them receptive to secondary stimulation by other lymphokines. In this case, antisense oligonucleotides to Ly-6 had no effect on secondary activation with IL-2, IL-4 + IL-1, or PMA + ionomycin. We conclude from these studies that Ly-6 expression is required for T cell receptor (TCR)-mediated T cell activation.
Additional file 1 of Synthetic CT generation from CBCT and MRI using StarGAN in the Pelvic Region
Creators: name: Wongtrakool, Paritt
name: Puttanawarut, Chanon
name: Changkaew, Pimolpun
name: Piasanthia, Supakiet
name: Earwong, Pareena
name: Stansook, Nauljun
name: Khachonkham, Suphalak
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Additional file 1.
Arbeitsbezogenes Erleben von Lehrkräften - Validierung eines mehrdimensionalen Messinstruments [Einzelbeitrag]
Creators: name: Bauer, Karl-Oswald
name: Kemna, Pierre
Publisher: name: bildungsforschung
Year: 2010

description: Ausgehend von Theorien zur Lehrerprofessionalität, zur Selbstwirksamkeit, zum Burnout und zum Thema "Sinn" wird das mehrdimensionale Konstrukt eines arbeitsbezogenen Erlebens von Lehrkräften hergeleitet, operationalisiert und empirisch überprüft. Vier Dimensionen des Erlebens werden herausgefiltert, die erlebte pädagogische Wirksamkeit, das Schülerinteresse, das Vertrauen und das Wohlbefinden der Lehrpersonen in ihrem Arbeitsumfeld. Dazu wird ein Testinstrument entwickelt, das im Hinblick auf seine Kriteriumsvalidität und seine Konstruktvalidität an einer Stichprobe von N = 413 Lehrkräften erprobt wird. Getestet wird ein Netzwerk von Propositionen, das sich vor allem auf Zusammenhänge zwischen den vier Subdimensionen und Schulleitungsqualität, Unterrichtsqualität, Burnoutrisiko sowie der Schulform bezieht.
description: bildungsforschung, Bd. 2 (2009): Medien statt Gedächtnis
Use of diverse growth models to estimate annual survival from mean size in a sample: examples using sea urchins
Creators: name: EBERT, Thomas A.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2013

description: Various models have been used to describe sea urchin growth including the von Bertalanffy, Richards, logistic, Tanaka, Gaussian, Gompertz, logistic dose response, and one derived from the Gamma function. Data from three sea urchins, Mesocentrotus (Strongylocentrotus) franciscanus, Echinometra mathaei, and Stomopeustes variolaris, tagged with tetracycline were used to order models based on levels of support determined by the wi measure of the Akaike's Information Criterion. Growth parameters were combined with the mean of measured size-frequency data to estimate survival and showed that estimates were insensitive to the growth model selected.
Zum Thema: Technologie verändert die Bildungsforschung
Creators: name: Baumgartner, Peter
name: Schaffert, Sandra
Publisher: name: bildungsforschung
Year: 2010

description: In diesem Beitrag wird eine Einführung zur Ausgabe 2 (2007) der "bildungsforschung" mit dem Themenschwerpunkt "Technologie verändert die Bildungsforschung" gegeben.
description: bildungsforschung, Bd. 2 (2007): Technologie verändert die Bildungsforschung
BIOMETRIC DIFFERENCES BETWEEN DOGFISH (SCYLIORHINUS-CANICULA) EMBRYOS FROM THE CHANNEL AND MEDITERRANEA, AND THEIR YOLK SACS, WITH A NEW DESCRIPTION OF THE HATCHING STAGE
Creators: name: Mellinger, J.
name: Wrisez, F.
name: Alluchongerard, M. J.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1984

Abstract
Report on a Boston University Conference December 7-8, 2012 on 'How Can the History and Philosophy of Science Contribute to Contemporary U.S. Science Teaching?'
Creators: name: Garik, Peter
name: Benétreau-Dupin, Yann
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics Education (physics.ed-ph)
subject: History and Philosophy of Physics (physics.hist-ph)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: This is an editorial report on the outcomes of an international conference sponsored by a grant from the National Science Foundation (NSF) (REESE-1205273) to the School of Education at Boston University and the Center for Philosophy and History of Science at Boston University for a conference titled: How Can the History and Philosophy of Science Contribute to Contemporary U.S. Science Teaching? The presentations of the conference speakers and the reports of the working groups are reviewed. Multiple themes emerged for K-16 education from the perspective of the history and philosophy of science. Key ones were that: students need to understand that central to science is argumentation, criticism, and analysis; students should be educated to appreciate science as part of our culture; students should be educated to be science literate; what is meant by the nature of science as discussed in much of the science education literature must be broadened to accommodate a science literacy that includes preparation for socioscientific issues; teaching for science literacy requires the development of new assessment tools; and, it is difficult to change what science teachers do in their classrooms. The principal conclusions drawn by the editors are that: to prepare students to be citizens in a participatory democracy, science education must be embedded in a liberal arts education; science teachers alone cannot be expected to prepare students to be scientifically literate; and, to educate students for scientific literacy will require a new curriculum that is coordinated across the humanities, history/social studies, and science classrooms.
description: Conference funded by NSF grant REESE-1205273. 31 pages
Die Verflechtung von Technik und Bildung - Technikforschung in der Bildungsforschung
Creators: name: Klebl, Michael
Publisher: name: bildungsforschung
Year: 2010

description: Der Beitrag stellt Ansätze vor, die im Rahmen der Bildungsforschung Wechselwirkungen zwischen Technik und Bildung erklären können. Auf der Grundlage der sozialwissenschaftlichen Technikforschung, vor allem der Social Construction of Technology (SCOT), wird ein analytischer Zugang zum Verhältnis von Technikentstehung bzw. -einsatz und Veränderungen im Bildungswesen erörtert. Ein Ausblick auf Gestaltungsoptionen in Form einer partizipativen Technikgestaltung schließt den Beitrag ab.
description: bildungsforschung, Bd. 2 (2007): Technologie verändert die Bildungsforschung
An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity
Creators: name: Eisenberg, Robert A.
name: Sobel, Eric S.
name: Morris, Suzanne C.
name: Katagiri, Koko
name: Cohen, Philip L.
name: Katagiri, Takuya
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1991

description: Mice homozygous for the gene lpr develop marked lymphadenopathy and a spectrum of autoantibodies closely resembling that of human systemic lupus erythematosus. The unusual T cell phenotype of the expanded lymphocyte population and the T-dependence of several antibodies in this strain have suggested that primary T cell abnormalities underlie the autoimmune syndrome. Using double chimeras, we now show that expression of the lpr gene in B cells is absolutely necessary for autoantibody production. Combinations of anti-Thy 1.2 + C' treated bone marrow from congenic strains of C57BL/6 mice, differing only at the immunoglobulin heavy chain (Igh) and lpr loci, were transferred into lethally irradiated B6/lpr mice. Double chimerism was documented by allotype-specific surface IgD and IgM immunofluorescence assay of peripheral blood and by allotype-specific enzyme-linked immunosorbent assay for total IgM in serum. Despite the presence of both +/+ and lpr B cells, IgM and IgG2a anti-chromatin as well as IgM anti-IgG were entirely the products of lpr B cells. Total serum IgG2a and IgG1 were also dominated by the lpr phenotype but not to the same extent. A similar experiment using B6/lpr-Igha recipients confirmed these findings. Additional experiments in which B6/lpr recipients were infused with ratios of donor bone marrow favoring B6.C20 +/+ over B6/lpr showed that even though +/+ B cells were overrepresented, autoantibodies were only of the lpr allotype. In addition, in the presence of lpr B cells, normal B cells showed little response to an exogenous, T cell-dependent antigen. The data thus indicate that lpr B cells manifest an intrinsic abnormality which is essential for autoantibody production in the lpr model.
Professionelle Literaturrecherche und -verwaltung im Web [Praxisbericht]
Creators: name: Schaffert, Sandra
Publisher: name: bildungsforschung
Year: 2010

description: In diesem Beitrag werden Hinweise für eine professionelle Literaturrecherche und -verwaltung im World Wide Web gegeben. Dazu werden einschlägige Literaturdatenbanken genannt, insbesondere solche, die kostenlos zu nutzen sind. Außerdem werden Tipps für clevere Recherchen sowie eine kurze Übersicht über Web-Werkzeuge zur Verwaltung von bibliografischen Angaben gegeben.
description: bildungsforschung, Bd. 2 (2007): Technologie verändert die Bildungsforschung
Ammar's Theory: A Scientific Framework for Multi-Dimensional Energy and Superluminal Travel
Creators: name: Ammar, Yasir
name: Valamontes Center For Scientific Publication
Publisher: name: Zenodo
Year: 2025

description: This paper introduces Ammar’s Theory, a new scientific framework to explore the concept of multi-dimensional energy, superluminal travel, and the hierarchical structure of energy sources beyond con-ventional physics. The theory challenges the notion of light as the ultimate speed limit by proposinghigher-order energy forms capable of surpassing known light-speed constraints. This work extends Ein-stein’s relativity, integrates quantum gravitational effects, and introduces novel variables and equationsto mathematically model travel beyond known light-speed barriers.
(3759) John White
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Asymmetric Reduction of Pyridinium Salts to Piperidines
Creators: name: Zhang, Shiyu
Publisher: name: University of Liverpool Repository
Year: 2021

description: Piperidines, especially chiral piperidines, have served as important structural motifs due to their great value in pharmaceutical chemistry during the last several decades. Many chemists have focused their attention on the synthesis of piperidines with different methods. However, the asymmetric hydrogenation (AH) of pyridine derivatives is one of the most straightforward and efficient ways to access chiral piperidines compared with other methods. As a part of AH, asymmetric transfer hydrogenation (ATH) is a safer and operationally simpler reduction method. Nonetheless, the ATH of pyridine derivatives to prepare chiral piperidines has rarely been reported. In this thesis, we will present our contribution to the synthesis of chiral piperidines via ATH. Chapter 1 describes recent development on the synthesis of piperidines, especially chiral piperidines. Following an introduction to recent development in asymmetric hydrogenation to synthesis chiral piperidines in Chapter 1, Chapter 2 depicts how to prepare 2 or 3-substituted pyridinium salts. Chapter 3 describes the synthesis of chiral piperidines without hydrogenation in detail. From this section, we can find the pros and cons of this method. Experimental detail and NMR spectrums are provided in Chapter 4.
(3762) Louisa Stewart
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Reflexives Lernen in der Erwachsenenbildung - zwischen Irritation und Kohärenz
Creators: name: Schüßler, Ingeborg
Publisher: name: bildungsforschung
Year: 2010

description: Der Beitrag verweist anhand arbeitsstruktureller und gesellschaftlicher Veränderungen auf die zunehmende Bedeutung reflexiver Wissensformen. Er geht dabei der Frage nach, wie Reflexionskompetenz im Rahmen organisierter Erwachsenenbildung gefördert werden kann. Dabei wird die These entfaltet, dass nachhaltiges Lernen Irritationen und ihre reflexive Verarbeitung voraussetzt, mit dem Ziel der Wiedergewinnung biographischer Kohärenz. Anhand empirischen Materials werden reflexive Lernformen exemplarisch präsentiert und im Hinblick auf die Herausforderungen an die Lernprozessgestaltung und Professionalität der Lehrenden analysiert.
description: bildungsforschung, Bd. 2 (2008): Reflexives Lernen
Yarkovsky effect in Generalized Photogravitational 3-Bodies Problem
Creators: name: Ershkov, Sergey V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences
subject: 70F15, 70F07

description: Here is presented a generalization of photogravitational restricted 3-bodies problem to the case of influence of Yarkovsky effect, which is known as reason of additional infinitesimal acceleration of a small bodies in the space (due to anisotropic re-emission of absorbed energy from the sun, other stellar sources). Asteroid is supposed to move under the influence of gravitational forces from 2 massive bodies (which are rotating around their common centre of masses on Kepler trajectories), as well under the influence of pressure of light from both the primaries. Analyzing the ODE system of motion, we explore the existense of equilibrium points for a small body (asteroid) in the case when the 2-nd primary is non-oblate spheroid. In such a case, it is proved the existence of maximally 256 different non-planar libration points in generalized photogravitational restricted 3-bodies problem when we take into consideration even a small Yarkovsky effect.
description: 12 pages; key words: Yarkovsky effect, YORP-effect, photogravitational restricted three body problem, stability, equilibrium points, libration points, oblateness
Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice
Creators: name: Sobel, Eric S.
name: Keap, Elizabeth A.
name: Cohen, Philip L.
name: Eisenberg, Robert A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Mice homozygous for the lpr gene develop autoantibodies and polyclonal B cell activation similar to what is seen in human systemic lupus erythematosus patients. We have previously shown that an lpr-specific intrinsic B cell defect was necessary for autoantibody production in this model. In the current study, we have further defined these autoantibody-producing B cells. Two major subsets of B cells have been described. B-1 cells (CD5+ B cells) can be distinguished from conventional B cells on the basis of phenotype, cytokine secretion, gene expression, anatomical location, and function. In addition, B-1 cells have been implicated in autoimmunity in several murine and human studies. To address the question of which B cell subset produces autoantibodies in lpr mice, we used immunoglobulin heavy chain (Igh) allotype-marked peritoneal (B-1 cell source) and bone marrow (conventional B cell source) cells from lpr mice to establish B cell chimeras. We used two general approaches. In one, we reconstituted sublethally irradiated mice with B-1 cells of one allotype and bone marrow cells of another allotype. In the second method, we suppressed endogenous B cells in neonatal mice with allotype-specific anti-IgM antibody, and injected peritoneal cells of another allotype. After antibody treatment was stopped, the mouse's conventional B cells recovered, but the B-1 subset was only reconstituted by the donor. In both types of chimeras, antichromatin, rheumatoid factor, and anti- single stranded DNA (ssDNA) autoantibodies were produced by the conventional B cell bone marrow source. In addition, an age-related decrease in peritoneal B-1 cells was seen, even in unmanipulated lpr mice. These data show that lpr B-1 cells are not important producers of autoantibodies. Conventional B cells are the source of autoantibodies directed at chromatin, ssDNA, and IgG.
Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA
Creators: name: Newburger, Peter E.
name: Maly, Friedrich E.
name: Curnutte, John T.
name: Dinauer, Mary C.
name: Cochrane, Charles G.
name: Quilliam, Lawrence
name: Schuerer-Maly, Cornelia C.
name: Gifford, Mary
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: The respiratory burst oxidase of phagocytes and B lymphocytes is a multicomponent enzyme that catalyzes the one-electron reduction of oxygen by NADPH. It is responsible for the O2-production that occurs when these cells are exposed to phorbol 12-myristate 13-acetate or physiologic stimuli, such as phagocytosis in phagocytes or cross- linking of surface immunoglobulin in B lymphocytes. The activity of this enzyme is greatly diminished or absent in patients with chronic granulomatous disease (CGD), an inherited disorder characterized by a severe defect in host defense against bacteria and fungi. In every CGD patient studied so far, an abnormality has been found in a gene encoding one of the four components of the respiratory burst oxidase: the membrane proteins p22phox or gp91phox which together form the cytochrome b558 protein, or the cytosolic proteins p47phox or p67phox. Autosomal recessive cytochrome-negative CGD (A22(0) CGD) is associated with mutations in the gene coding for p22phox. We report here that the capacity for O2- production and cytochrome b558 protein expression were restored to Epstein-Barr virus-transformed B lymphocytes from two A22(0) CGD patients by transfection with an expression plasmid containing a p22phox cDNA. No detectable O2- was generated by untransfected p22phox-deficient lymphocytes. The genetic reconstitution of the respiratory burst in A22(0) CGD B lymphocytes by transfer of the wild-type p22phox cDNA represents a further step towards somatic gene therapy for this subgroup of A22(0) CGD. This system will also be useful for expression of genetically engineered mutant p22phox proteins in intact cells, facilitating the structure-function analysis of cytochrome b558.