cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The role of the MEK/ERK pathway in regulating cytoskeleton-dependent B cell responses to immobilized and cell-bound antigens
Creators: name: Peters, Victoria
Publisher: name: University of British Columbia
Year: 2020

description: The immune synapse (IS) is a special polarized structure that optimizes the functions of the B cell receptor (BCR), signal transduction and antigen internalization. The B cell IS is formed when B cells bind antigens (Ags) that are displayed on the surface of Ag-presenting cells (APCs), creating an area of contact between the two cells. The binding of the BCR to the Ag on the APC triggers rapid and dynamic reorganization of the BCRs and the cytoskeleton. This allows the cell to spread across the surface of the APC and induces the formation of BCR microclusters throughout the contact site. The microclusters then move centripetally and coalesce into the central supramolecular activation cluster (cSMAC) of an IS. A major signaling pathway initiated by the binding of the BCR to Ags is the Ras/MEK/ERK pathway. Although ERK activity has been implicated in B cell survival and proliferation, the role of ERK in regulating BCR-induced cytoskeletal reorganization, IS formation, and APC-induced BCR signaling has not been investigated. I showed that ERK activity is important for B cells to spread on immobilized Ag. Inhibiting ERK resulted in decreased spreading and altered actin organization. By imaging B cell-APC interactions, I also showed that inhibiting ERK activity impaired IS formation, resulting in decreased APC-induced BCR signaling and delayed cSMAC formation. Thus, ERK may regulate actin-dependent processes that are important for B cell responses to immobilized and APC-bound Ags.
Additional file 4 of Appointment structure in Malaysian healthcare system during the COVID-19 pandemic: The public perspective
Creators: name: Subramaniam Kalianan, Ramani
name: Woon, Yuan Liang
name: Hing, Yee Liang
name: Leong, Chin Tho
name: Lim, Wei Yin
name: Loo, Ching Ee
name: Low, Lee Lan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Additional file 4. Reasons for agreeing on after 5pm weekday appointments.
title: ÐÐ²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð°Ñ ÑÐ¸ÑÑÐµÐ¼Ð° ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐ¾Ð¹ Ð´ÐµÐ³Ð°Ð·Ð°ÑÐ¸Ð¸ Ð²Ð¾Ð´Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Automated control system of installation for the degassing of water
Creators: name: ÐÐ°Ð¿ÑÐ¾Ð²Ð°, ÐÐ½Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸Ð¾Ð²Ð°Ð½Ð½Ð°Ñ ÑÐ¸ÑÑÐµÐ¼Ð° ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐ¾Ð¹ Ð´ÐµÐ³Ð°Ð·Ð°ÑÐ¸Ð¸ Ð²Ð¾Ð´Ñ
ÐÐÐ ÐâÐ­
ÐÐÐ â ÑÐµÐ³ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ñ Ð¿ÑÐ¾ÑÐµÑÑÐ° Ð´ÐµÐ³Ð°Ð·Ð°ÑÐ¸Ð¸ Ð²Ð¾Ð´Ñ
automated control system for water degassing installation
MORE-E
PID-control
automation of water degassing process

description: Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð²Ð¾Ð¿ÑÐ¾ÑÑ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐ¾Ð¹ ÐÐÐ Ð-Ð­, ÐºÐ¾ÑÐ¾ÑÐ°Ñ Ð¿ÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð° Ð´Ð»Ñ Ð´ÐµÐ³Ð°Ð·Ð°ÑÐ¸Ð¸ Ð²Ð¾Ð´Ñ. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð° ÑÐ¸ÑÑÐµÐ¼Ð° ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐ¾Ð¹ Ð¸ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð°, ÐºÐ¾ÑÐ¾ÑÐ°Ñ Ð¾ÑÐ¾Ð±ÑÐ°Ð¶Ð°ÐµÑ ÑÐ¾ÑÑÐ¾ÑÐ½Ð¸Ðµ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐ¸. ÐÐ°Ð½Ð½Ð°Ñ ÑÐ¸ÑÑÐµÐ¼Ð° Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÐµÑ Ð¿Ð¾Ð»ÑÑÐ°ÑÑ Ð¸ Ð¾Ð±ÑÐ°Ð±Ð°ÑÑÐ²Ð°ÑÑ Ð´Ð°Ð½Ð½ÑÐµ Ð¾ ÑÐ¾ÑÑÐ¾ÑÐ½Ð¸Ð¸ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐ¸ Ð¸ Ð²ÑÐ²Ð¾Ð´Ð¸ÑÑ Ð¸Ñ Ð½Ð° ÑÐºÑÐ°Ð½. Ð£Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ Ð½Ð°ÑÐ¾ÑÐ¾Ð¼ Ð¾ÑÑÑÐµÑÑÐ²Ð»ÑÐµÑÑÑ Ð¿ÑÐ¸ Ð¿Ð¾Ð¼Ð¾ÑÐ¸ ÐÐÐ-ÑÐµÐ³ÑÐ»ÑÑÐ¾ÑÐ°. Ð ÐµÐ³ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÐµÑ Ð¾Ð¿ÑÐ¸Ð¼Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°ÑÑ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ Ð¸ ÑÐ»ÑÑÑÐ¸ÑÑ ÐºÐ°ÑÐµÑÑÐ²Ð¾ Ð¿ÐµÑÐµÑÐ¾Ð´Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¾ÑÐµÑÑÐ°.
description: The questions of automation of control of the installation SEA-e, which designed for water degassing. An installation control system and a program that displays the installation state has been developed. This system allows you to receive and process data on the status of the installation and display it on the screen. The pump is controlled by a PID-controller. Regulation allows you to optimize control and improve the quality of the transition process.
Fermion localization on branes with generalized dynamics
Creators: name: Castro, Luis B.
name: Meza, Luis E. Arroyo
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this letter we consider a specific model of braneworld with nonstandard dynamics diffused in the literature, specifically we focus our attention on the matter energy density, the energy of system, the Ricci scalar and the thin brane limit. As the model is classically stable and capable of localize gravity, as a natural extension we address the issue of fermion localization of fermions on a thick brane constructed out from one scalar field with nonstandard kinetic terms coupled with gravity. The contribution of the nonstandard kinetic terms in the problem of fermion localization is analyzed. It is found that the simplest Yukawa coupling $η\barΨϕΨ$ support the localization of fermions on the thick brane. It is shown that the zero mode for left-handed can be localized on the thick brane depending on the values for the coupling constant $η$.
description: 6 pages, 3 figures
Relaxation and derelaxation of pure and hydrogenated amorphous silicon during thermal annealing experiments
Creators: name: Kail, F.
name: Farjas, J.
name: Roura, P.
name: Secouard, C.
name: Nos, O.
name: Bertomeu, J.
name: Alzina, F.
name: Cabarrocas, P. Roca i
Publisher: name: arXiv
Year: 2010
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The structural relaxation of pure amorphous silicon (a-Si) and hydrogenated amorphous silicon (a-Si:H) materials, that occurs during thermal annealing experiments, has been analysed by Raman spectroscopy and differential scanning calorimetry. Unlike a-Si, the heat evolved from a-Si:H cannot be explained by relaxation of the Si-Si network strain, but it reveals a derelaxation of the bond angle strain. Since the state of relaxation after annealing is very similar for pure and hydrogenated materials, our results give strong experimental support to the predicted configurational gap between a-Si and crystalline silicon.
description: 15 pages, 3 figures, 1 table to be published in Applied Physics Letters
Approximation of holomorphic maps from Runge domains to affine algebraic varieties
Creators: name: Bilski, Marcin
name: Parusinski, Adam
Publisher: name: arXiv
Year: 2011
Subjects: subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: 32E30, 32S15, 32S45

description: We present a geometric proof of the theorem saying that holomorphic maps from Runge domains to affine algebraic varieties admit approximation by Nash maps. Next we generalize this theorem.
description: 24 pages; Proposition 3.3 of v1 is replaced in v2 by a much simpler Proposition 4.2; Proof of Proposition 3.6 of v1 is simplified (see Proposition 4.3 in v2); Proof of the main theorem is simplified, its outline and generalization are added
Tante idee, un'unica storia: lo sviluppo della collaborazione in una pluriclasse di prima e seconda elementare attraverso la fiaba
Creators: name: Frongillo, Sofia
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2022
Subjects: collaborazione – approccio Chambers – fiaba – invenzione di storie – storie divergenti

description: Per questa tesi è stata condotta una ricerca in una classe di prima e seconda elementare composta da quindici allievi ed è stato impiegato un approccio di tipo applicativo. Il lavoro indaga le modalità attraverso le quali possono realizzarsi forme di collaborazione grazie alla riscrittura di una fiaba classica. In questo caso, dei bambini di prima e di seconda elementare hanno dovuto collaborare con l’obiettivo di creare una fiaba divergente a partire dal libro Cappuccetto Rosso, Verde, Giallo, Blu e Bianco. Inizialmente, i bambini sono stati introdotti al tema grazie alla riproposta di fiabe classiche come quelle di Hänsel e Gretel, Biancaneve e i sette nani e I tre porcellini. Al termine di ogni fiaba è poi stata svolta una discussione seguendo l’approccio “Tell me” di Aidan Chambers, che ha permesso ai bambini di riflettere e di collaborare condividendo le proprie idee. Durante la fase di sperimentazione, i bambini hanno dovuto ricreare a gruppi una fiaba divergente, partendo da un testo di Munari ascoltato e discusso in classe. I gruppi sono stati cinque, ciascuno dei quali composto da tre allievi che hanno dovuto collaborare per poter creare una storia divergente di Cappuccetto Rosso cambiandone il colore. Grazie ai risultati ottenuti è possibile notare come la struttura della fiaba sia stata compresa e come trattarla e discuterla attraverso l’approccio “Tell me” abbia favorito lo sviluppo della collaborazione sia con la classe sia all’interno del gruppo di scrittura. Relatore: Luca Cignetti.
A conjugacy criterion for Hall subgroups in finite groups
Creators: name: Revin, D. O.
name: Vdovin, E. P.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20D20, 20E34

description: A finite group $G$ is said to satisfy $C_π$ for a set of primes $π$, if $G$ possesses exactly one class of conjugate $π$-Hall subgroups. In the paper we obtain a criterion for a finite group $G$ to satisfy $C_π$ in terms of a normal series of the group.
description: Appear in Siberian Mathematical Journal, vol. 51 (2010), No3.
Additional file 1: of Characterization of bHLH/HLH genes that are involved in brassinosteroid (BR) signaling in fiber development of cotton (Gossypium hirsutum)
Creators: name: Lu, Rui
name: Zhang, Jiao
name: Liu, Dong
name: Wei, Ying-Li
name: Wang, Yao
name: Li, Xue-Bao
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology
subject: Computational Biology

description: Table S1. The bHLH/HLH gene family of cotton (Gossypium hirsutum). Figure S1. Phylogenetic relationship of cotton (Gossypium hirsutum) bHLH/HLH transcription factors with those of Arabidopsis and rice. Table S2. Phylogenetic classification and known biological functions of bHLH/HLH proteins from Arabidopsis and cotton (Gossypium hirsutum). Figure S2. Conserved motifs of GhbHLH/HLH proteins. Figure S3. Heatmap representation for expression profiles of cotton (G. hirsutum) bHLH/HLH genes in cotton tissues. Table S3. Primers used in quantitative RT-PCR analysis. (PDF 704 kb)
Time-resolved measurement of Landau--Zener tunneling in different bases
Creators: name: Tayebirad, G.
name: Zenesini, A.
name: Ciampini, D.
name: Mannella, R.
name: Morsch, O.
name: Arimondo, E.
name: Lörch, N.
name: Wimberger, S.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: A comprehensive study of the tunneling dynamics of a Bose--Einstein condensate in a tilted periodic potential is presented. We report numerical and experimental results on time-resolved measurements of the Landau--Zener tunneling of ultracold atoms introduced by the tilt, which experimentally is realized by accelerating the lattice. The use of different protocols enables us to access the tunneling probability, numerically as well as experimentally, in two different bases, namely, the adiabatic basis and the diabatic basis. The adiabatic basis corresponds to the eigenstates of the lattice, and the diabatic one to the free-particle momentum eigenstates. Our numerical and experimental results are compared with existing two-state Landau--Zener models.
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¿ÑÐ¾ÐµÐºÑÐ° Ð³Ð¾ÑÐ¾Ð´ÑÐºÐ¾Ð³Ð¾ Ð¼Ð¾ÑÑÐ°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: The development of the project the city bridge
Creators: name: Ð¨ÐµÐ³ÑÑÐ¾Ð², ÐÐ¸ÐºÐ¸ÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: Ð³Ð¾ÑÐ¾Ð´ÑÐºÐ¾Ð¹ Ð¼Ð¾ÑÑ
ÑÑÐ°Ð»ÐµÐ¶ÐµÐ»ÐµÐ·Ð¾Ð±ÐµÑÐ¾Ð½Ð½ÑÐµ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸
Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
ÐºÐ¾Ð½ÑÑÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
ÑÐµÐºÐ° ÐÐ°ÑÐ¿Ð¾Ð²ÐºÐ°
ÑÐµÑ Ð½Ð¸ÐºÐ¾-ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ðµ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ
ÑÐ¼ÐµÑÐ½Ð°Ñ Ð´Ð¾ÐºÑÐ¼ÐµÐ½ÑÐ°ÑÐ¸Ñ
urban bridge
steelconcrete structures
design
construction
Karpovka river
techical-co-economis camparison
estimated documentation

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½ Ð¸ ÑÐ¾ÑÑÐ°Ð²Ð»ÐµÐ½ Ð¿ÑÐ¾ÐµÐºÑ Ð³Ð¾ÑÐ¾Ð´ÑÐºÐ¾Ð³Ð¾ Ð¼Ð¾ÑÑÐ° ÑÐµÑÐµÐ· ÑÐµÐºÑ ÐÐ°ÑÐ¿Ð¾Ð²ÐºÑ. ÐÐ°Ð½Ð¾ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ðµ ÑÐ°Ð¹Ð¾Ð½Ð° ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ð° Ð¼Ð¾ÑÑÐ°, Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ðµ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð²Ð° ÑÐµÑÐ½Ð¸ÐºÐ¾-ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ðµ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ Ð²Ð°ÑÐ¸Ð°Ð½ÑÐ¾Ð² Ð¼Ð¾ÑÑÐ¾Ð²Ð¾Ð³Ð¾ Ð¿ÐµÑÐµÑÐ¾Ð´Ð°. ÐÐ·ÑÑÐµÐ½Ð° ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ñ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿ÑÐ¾Ð»ÑÑÐ½ÑÑ ÑÑÑÐ¾ÐµÐ½Ð¸Ð¹ Ð¸ Ð±ÐµÑÐµÐ³Ð¾Ð²ÑÑ ÑÑÑÐ¾ÐµÐ². ÐÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ ÑÐ°ÑÑÐµÑ ÑÐ²Ð°Ð¹Ð½Ð¾Ð³Ð¾ ÑÑÐ½Ð´Ð°Ð¼ÐµÐ½ÑÐ° Ð¸ Ð¿ÑÐ¾Ð»ÑÑÐ½Ð¾Ð³Ð¾ ÑÑÑÐ¾ÐµÐ½Ð¸Ñ Ð½Ð° Ð´ÐµÐ¹ÑÑÐ²Ð¸Ðµ ÑÐ¾ÑÐµÑÐ°Ð½Ð¸Ð¹ Ð½Ð°Ð³ÑÑÐ·Ð¾Ðº. ÐÐ¾ÑÑÐ¸ÑÐ°Ð½Ð° ÑÐ¼ÐµÑÐ½Ð°Ñ ÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÑ Ð¾Ð±ÑÐµÐºÑÐ°, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ¾ÑÑÐ°Ð²Ð»ÐµÐ½ Ð¸ Ð¸ÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ð¿ÐµÑÐµÑÐµÐ½Ñ Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ð¾Ð² Ð² ÑÐ¾ÑÑÐ°Ð²Ðµ Ð¾Ð±ÑÐ·Ð°ÑÐµÐ»ÑÐ½ÑÑ Ðº Ð¾ÑÐ¾ÑÐ¼Ð»ÐµÐ½Ð¸Ñ ÑÐµÑÑÐµÐ¶ÐµÐ¹.
description: In this final qualifying work the project of the city bridge over the Karpovka river is stated and made. The description of the area of construction of the bridge, the description of the construction of technical and economic comparison of options of the bridge crossing. Studied design technology that spans the coast and foundations. The calculation of the pile Foundation and superstructure on the action of combinations of loads. The estimated cost of the object is calculated, and also the list of graphic materials as a part of drawings obligatory to registration is made and executed.
Additional file 1: of The role of podocyte damage in the etiology of ischemia-reperfusion acute kidney injury and post-injury fibrosis
Creators: name: Chen, Yi
name: Lin, Liyu
name: Tao, Xuan
name: Song, Yankun
name: Cui, Jiong
name: Wan, Jianxin
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Hematology

description: PCR primers and product sizes; PCR primers and product sizes of Nephrin, CD2AP, synaptopodin, TRPC6 and GADPH. (DOCX 16 kb)
Fueling the Digital Chemistry Revolution with Language Models
Creators: name: , Teodoro
Publisher: name: Zenodo
Year: 2022

description: One of the most important outcomes of organic chemistry is the creation of newly designed molecules. The application of domain knowledge gained through decades of laboratory experience has been critical in the synthesis of many new molecular structures. Nonetheless, most synthetic success stories are preceded by lengthy periods of unfruitful explorations. While automation systems proved exceptional in specific fields such as high-throughput chemistry, their use in general-purpose workflows remains a highly complex task, requiring the development of always unique software codifying distinct types of chemical operations. The digital revolution in chemistry hopes to streamline the adoption of digital models and automation with the use of data. In the last years, natural language processing models have emerged as one of the most effective, scalable approaches for capturing human knowledge and modelling chemical processes in organic chemistry. Its use in machine learning tasks demonstrated high quality and ease of use in problems such as predicting chemical reactions [1-2], retrosynthetic routes [3], digitizing chemical literature [4], predicting detailed experimental procedures [5], designing new fingerprints [6] and yield predictions [7]. In this talk, I'll talk about the impact of language models in chemistry by highlighting the critical role of NLP architectures in implementing the first cloud-based AI-driven autonomous laboratory [8].
 [1] IBM Research Europe, Chem. Sci., 2018, 9, 6091-6098
 [2] IBM Research Europe, ACS Cent. Sci. 2019, 5, 9, 1572-1583
 [3] IBM Research Europe, Chem. Sci., 2020, 11, 3316-3325
 [4] IBM Research Europe, Nat. Comm., 2020, 11, 3601
 [5] IBM Research Europe, Nat. Comm., 2021, 12, 2573
 [6] IBM Research Europe, Nat. Mach. Intel., 2021, 3, 144–152
 [7] IBM Research Europe, Mach. Learn.: Sci. Technol., 2021, 2, 015016
 [8] https://rxn.res.ibm.com
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÑÑÐ°ÑÐµÐ³Ð¸ÑÐµÑÐºÐ¸Ñ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ð¹ Ð¿Ð¾ Ð¾ÑÐºÑÑÑÐ¸Ñ Ð½Ð¾Ð²Ð¾Ð³Ð¾ ÑÐ¸Ð»Ð¸Ð°Ð»Ð° Ð´ÐµÐ¹ÑÑÐ²ÑÑÑÐµÐ³Ð¾ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Development of strategic measures for the opening of a new branch of the operating enterprice
Creators: name: Ð¡ÑÐµÐ¿Ð°Ð½Ð¾Ð²Ð°, ÐÐ»ÐµÐºÑÐ°Ð½Ð´ÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: Ð¸Ð½Ð²ÐµÑÑÐ¸ÑÐ¸Ð¾Ð½Ð½Ð¾Ðµ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
Ð°Ð½Ð°Ð»Ð¸Ð· Ð¿Ð¾ÑÑÐµÐ±Ð¸ÑÐµÐ»ÐµÐ¹
ÐºÐ¾Ð½ÐºÑÑÐµÐ½ÑÐ¸Ñ
ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð·
ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¸Ð½Ð²ÐµÑÑÐ¸ÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¾ÐµÐºÑÐ°
investment planning
consumer analysis
competition
financial analysis
development of investment project

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ ÐÐÐ Â«ÐÐ¸ÑÐ°Ð½ ÑÐµÐ²ÐµÑÐ¾-Ð·Ð°Ð¿Ð°Ð´Â».
Ð¦ÐµÐ»ÑÑ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÑÑÐ°ÑÐµÐ³Ð¸ÑÐµÑÐºÐ¸Ñ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ð¹ Ð¿Ð¾ Ð¾ÑÐºÑÑÑÐ¸Ñ Ð½Ð¾Ð²Ð¾Ð³Ð¾ ÑÐ¸Ð»Ð¸Ð°Ð»Ð° Ð´ÐµÐ¹ÑÑÐ²ÑÑÑÐµÐ³Ð¾ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ.
Ð ÑÐ¾Ð´Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð±ÑÐ» Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð²Ð½ÐµÑÐ½ÐµÐ¹ Ð¸ Ð²Ð½ÑÑÑÐµÐ½Ð½ÐµÐ¹ ÑÑÐµÐ´Ñ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ, Ð²ÑÑÐ²Ð»ÐµÐ½Ñ ÐµÐ³Ð¾ ÑÐ¸Ð»ÑÐ½ÑÐµ Ð¸ ÑÐ»Ð°Ð±ÑÐµ ÑÑÐ¾ÑÐ¾Ð½Ñ, Ð° ÑÐ°ÐºÐ¶Ðµ Ð³Ð»Ð°Ð²Ð½ÑÐµ ÑÐ³ÑÐ¾Ð·Ñ Ð¸ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÐ¸.
ÐÐ° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° ÑÑÐ½ÐºÐ° ÑÐ¸Ð»Ð¾Ð²Ð¾Ð¹ ÑÐµÑÐ½Ð¸ÐºÐ¸ Ð±ÑÐ»Ð¸ Ð²ÑÑÐ²Ð»ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÐºÐ¾Ð½ÐºÑÑÐµÐ½ÑÑ ÐÐÐ Â«ÐÐ¸ÑÐ°Ð½ ÑÐµÐ²ÐµÑÐ¾-Ð·Ð°Ð¿Ð°Ð´Â».
ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð´ÐµÐ¹ÑÑÐ²ÑÑÑÐµÐ³Ð¾ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ, Ð¿Ð¾ÑÑÐ¸ÑÐ°Ð½Ñ Ð¸ Ð¿ÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð³ÑÑÐ¿Ð¿Ñ ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²ÑÑ ÐºÐ¾ÑÑÑÐ¸ÑÐ¸ÐµÐ½ÑÐ¾Ð².
ÐÑÐ»Ð° Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐµ Ð¸Ð½Ð²ÐµÑÑÐ¸ÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¾ÐµÐºÑÐ°, ÑÐ°ÑÑÐµÑÐ° Ð¾Ð±ÑÐµÐ¼Ð¾Ð² ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸, Ð° ÑÐ°ÐºÐ¶Ðµ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½ ÑÐ°ÑÑÐµÑ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÐµÐ¹ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸.
description: The object of the study is OOO Â«Lifan North-WestÂ».
The goal of the final qualifying work is the development of strategic measures for the opening of a new branch of the operating enterprise.
A comprehensive analysis of the external and internal environment of the enterprise was carried out, strengths and weaknesses were identified , as well as the main threats and opportunities were identified.
Based on the analysis of the market of power equipment the main competitors of OOO Â«Lifan North-WestÂ» were identified.
A financial analysis of the existing company was carried out, the main groups of financial ratios were calculated and analyzed.
Work was carried out on the development of the investment project, calculation of sales volumes, cash flows, as well as the calculation of performance indicators.
title: ÐÐ¸Ð·Ð°Ð¹Ð½-Ð¿ÑÐµÐ¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ðµ ÑÐ¾Ð¿Ð¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð¾ÑÐ½Ð¾Ð²Ñ Ð² Ð¿ÐµÑÐ°ÑÐ½ÑÑ Ð¸ ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð½ÑÑ Ð¸Ð·Ð´Ð°Ð½Ð¸ÑÑ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Design-transformation of topographic basis in printed and electronic editions
Creators: name: ÐÐµÑÑÐ¸ÑÐºÐ°Ñ, ÐÐ½Ð°ÑÑÐ°ÑÐ¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: Ð¥ÑÐ´Ð¾Ð¶ÐµÑÑÐ²ÐµÐ½Ð½Ð¾Ðµ ÐºÐ¾Ð½ÑÑÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
Ð¢Ð¾Ð¿Ð¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÐºÐ°ÑÑÑ
ÑÑÑÐ¸ÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¸ ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÐºÐ°ÑÑÑ
Ð¿ÑÐµÐ¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ðµ ÑÐ¾Ð¿Ð¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð¾ÑÐ½Ð¾Ð²Ñ
Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð´Ð¸Ð·Ð°Ð¹Ð½
Ð¸ÐºÐ¾Ð½ÐºÐ¸
Ð¿ÐµÑÐ°ÑÐ½ÑÐµ Ð¸Ð·Ð´Ð°Ð½Ð¸Ñ
Ð·Ð½Ð°ÐºÐ¾Ð²Ð°Ñ ÑÐ¸ÑÑÐµÐ¼Ð°
Ð´Ð¸Ð·Ð°Ð¹Ð½-Ð¿ÑÐ¾ÐµÐºÑ

description: Ð¦ÐµÐ»ÑÑ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ ÑÐ¿Ð¾ÑÐ¾Ð±Ð¾Ð² Ð¿ÑÐµÐ¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¾Ð¿Ð¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð¾ÑÐ½Ð¾Ð²Ñ Ð² Ð·Ð°Ð²Ð¸ÑÐ¸Ð¼Ð¾ÑÑÐ¸ Ð¾Ñ Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð¸Ñ ÐºÐ°ÑÑÑ. Ð ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð¾Ð±Ð·Ð¾Ñ Ð·Ð½Ð°ÐºÐ¾Ð²ÑÑ Ð¾Ð±ÑÐ°Ð·ÑÐ¾Ð² Ð³ÐµÐ¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ñ ÐºÐ°ÑÑ, Ð²ÑÐ²ÐµÐ´ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÑÐµÐ»Ð¸, Ñ ÐºÐ¾ÑÐ¾ÑÑÐ¼Ð¸ Ð¾Ð½Ð¸ ÑÐ¾Ð·Ð´Ð°Ð²Ð°Ð»Ð¸ÑÑ, Ð¸Ð·ÑÑÐµÐ½Ð¾, ÐºÐ°Ðº Ð¸Ð·Ð¼ÐµÐ½ÑÐ»Ð¸ÑÑ ÑÐ¿Ð¾ÑÐ¾Ð±Ñ Ð¾ÑÐ¾Ð±ÑÐ°Ð¶ÐµÐ½Ð¸Ñ ÑÐ¾Ð¿Ð¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð¾ÑÐ½Ð¾Ð²Ñ. ÐÐ·ÑÑÐµÐ½Ñ Ð¸ ÑÑÐ¾ÑÐ¼ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ñ Ð¿ÑÐ¸Ð½ÑÐ¸Ð¿Ñ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ ÑÑÑÐ¸ÑÑÐ¸ÑÐµÑÐºÐ¸Ñ ÐºÐ°ÑÑ. ÐÐ° Ð±Ð°Ð·Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð° Ð¾ÑÐ¸Ð³Ð¸Ð½Ð°Ð»ÑÐ½Ð°Ñ ÐºÐ¾Ð½ÑÐµÐ¿ÑÐ¸Ñ ÑÑÑÐ¸ÑÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÐºÐ°ÑÑÑ ÐÑÐ±Ð¾ÑÐ³Ð° Ð¸ Ð±ÑÐ¾ÑÑÑÑ-Ð¿ÑÑÐµÐ²Ð¾Ð´Ð¸ÑÐµÐ»Ñ.
description: The aim of the work is to study ways to transform the topographic base, depending on the purpose of the map. The masterâs thesis presents an analytical review of historical geographic maps, defining the main objectives with which they were created. Studied and formulated the principles of creating tourist maps. Based on the research, the original concept of a tourist map and a guide-brochure are proposed.
Ages and Luminosities of Young SMC/LMC Star Clusters and the recent Star Formation History of the Clouds
Creators: name: Glatt, Katharina
name: Grebel, Eva K.
name: Koch, Andreas
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: In this paper we discuss the age and spatial distribution of young (age$
description: 17 pages, 14 figures, Accepted for publication in A&A
The Galactic O-Star Spectroscopic Survey. I. Classification System and Bright Northern Stars in the Blue-Violet at R~2500
Creators: name: Sota, A.
name: Apellániz, J. Maíz
name: Walborn, N. R.
name: Alfaro, E. J.
name: Barbá, R. H.
name: Morrell, N. I.
name: Gamen, R. C.
name: Arias, J. I.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present the first installment of a massive spectroscopic survey of Galactic O stars, based on new, high signal-to-noise ratio, R~2500 digital observations from both hemispheres selected from the Galactic O-Star Catalog of Maíz Apellániz et al. (2004) and Sota et al. (2008). The spectral classification system is rediscussed and a new atlas is presented, which supersedes previous versions. Extensive sequences of exceptional objects are given, including types Ofc, ON/OC, Onfp, Of?p, Oe, and double-lined spectroscopic binaries. The remaining normal spectra bring this first sample to 184 stars, which is close to complete to B=8 and north of delta = -20 and includes all of the northern objects in Maíz Apellániz et al. (2004) that are still classified as O stars. The systematic and random accuracies of these classifications are substantially higher than previously attainable, because of the quality, quantity, and homogeneity of the data and analysis procedures. These results will enhance subsequent investigations in Galactic astronomy and stellar astrophysics. In the future we will publish the rest of the survey, beginning with a second paper that will include most of the southern stars in Maíz Apellániz et al. (2004).
description: Accepted for publication in ApJS. 73 pages and 20 figures. Figure 19 is shown at a degraded resolution due to arXiv limitations. If interested in the high-resolution version, please contact the author
Tracciare sentieri: esplorando l'influenza del WRW sull'autonomia nella scrittura nella comunità dei giovani autori
Creators: name: Hitz, Simona
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2024
Subjects: Autonomia di scrittura; Writing & Reading Workshop (WRW); processo di scrittura; scuola media; valutazione autentica.

description: La presente ricerca indaga l'influenza del Writing and Reading Workshop (WRW) sull'autonomia e la competenza nella scrittura di alunni di prima media. Adottando un approccio di ricerca misto, che combina metodi quantitativi e qualitativi, si mira a comprendere in modo più completo il fenomeno in esame. Lo studio coinvolge quattro studenti con differenti abilità nella scrittura, raccogliendo dati attraverso questionari, osservazioni in classe, colloqui individuali e analisi dei testi prodotti. I risultati evidenziano un impatto positivo del WRW sull'autonomia di scrittura, soprattutto per gli alunni che presentano iniziali difficoltà. Si osserva un miglioramento nella selezione degli elementi fondamentali per la creazione di testi, nella gestione del processo di scrittura e nella consapevolezza nell'autovalutazione dei propri lavori. Inoltre, si riscontra un incremento nella qualità e complessità dei testi prodotti, con un conseguente miglioramento nei risultati in scrittura. In conclusione, lo studio suggerisce che il WRW possa rappresentare una metodologia efficace per promuovere l'autonomia di scrittura, in particolare per coloro che affrontano iniziali difficoltà nella scrittura. Tuttavia, sembra che gli allievi già competenti riescano a trarre meno beneficio dagli strumenti offerti. Relatrice: Anna Bosia.
-- HATHOR -- HAdronic Top and Heavy quarks crOss section calculatoR
Creators: name: Aliev, M.
name: Lacker, H.
name: Langenfeld, U.
name: Moch, S.
name: Uwer, P.
name: Wiedermann, M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present a program to calculate the total cross section for top-quark pair production in hadronic collisions. The program takes into account recent theoretical developments such as approximate next-to-next-to-leading order perturbative QCD corrections and it allows for studies of the theoretical uncertainty by separate variations of the factorization and renormalization scales. In addition it offers the possibility to obtain the cross section as a function of the running top-quark mass. The program can also be applied to a hypothetical fourth quark family provided the QCD couplings are standard.
description: 24 pages, Latex, 1 figure
Electrocardiogram Analysis Reveals Ionic Current Dysregulation Relevant for Atrial Fibrillation
Creators: name: Dasí, Albert
name: Nagel, Claudia
name: Loewe, Axel
name: Camps, Julia
name: Bueno-Orovio, Alfonso
name: Rodriguez, Blanca
Publisher: name: Institute of Electrical and Electronics Engineers (IEEE)
Year: 2022

description: Antiarrhythmic drug choice for atrial fibrillation (AF) neglects the individual ionic current profile of the patient, even though it determines drug safety and efficacy. We hypothesize that the electrocardiogram (ECG) might contain information critical for pharmacological treatment personalization. Thus, this study aims to identify the extent of atrial ionic information embedded in the ECG, using multi-scale modeling and simulation. A dataset of 1,000 simulated ECGs was computed using a population of human-based whole-atria models with 200 individual ionic profiles and 5 different torso-atria orientations. A regression neural network was built to predict key atrial ionic conductances based on P- and T$_a$ -wave biomarkers. The neural network predicted, with >80% precision, the density of seven ionic currents relevant for AF, namely, ultra-rapid (I$_{Kur}$ ), rapid (I$_{Kr}$ ), outward transient (I$_{to}$ ), inward rectifier K$^+$ (I$_{K1}$ ), L-type Ca$^{2+}$ (I$_{CaL}$ ), Na$^+$ /K$^+$ pump (I$_{NaK}$ ) and fast Na$^+$ (I$_{Na}$) currents. These ionic densities were identified through the P- (i.e., I$_{Na}$), Ta - (i.e., I$_{K1}$ , I$_{NaK}$) or both waves (i.e., I$_{Kur}$ , I$_{Kr}$ , I$_{to}$ , I$_{CaL}$), providing a non- invasive characterization of the atrial electrophysiology. This could improve patient stratification and cardiac safety and the efficacy of AF pharmacological treatment.
On Classical Dynamics of Affinely-Rigid Bodies Subject to the Kirchhoff-Love Constraints
Creators: name: Kovalchuk, Vasyl
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In this article we consider the affinely-rigid body moving in the three-dimensional physical space and subject to the Kirchhoff-Love constraints, i.e., while it deforms homogeneously in the two-dimensional central plane of the body it simultaneously performs one-dimensional oscillations orthogonal to this central plane. For the polar decomposition we obtain the stationary ellipsoids as special solutions of the general, strongly nonlinear equations of motion. It is also shown that these solutions are conceptually different from those obtained earlier for the two-polar (singular value) decomposition.
Optical non-reciprocity in magnetic structures related to high-Tc superconductors
Creators: name: Orenstein, J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Recent neutron scattering [1,2], and optical measurements [3,4] have detected evidence in underdoped cuprate superconductors for a phase transition near the pseudogap onset temperature T* to a time reversal-breaking state. The neutron scattering indicates antiferromagnetic ordering, while it is often assumed that optical polarization rotation requires at least a weak ferromagnetic component. In this note we identify several antiferromagnetic structures, compatible with neutron scattering data, that allow intrinsic polarization rotation through the magnetoelectic effect.
Red tiles, white mosaic : Indigeneity and the institutionalization of multiculturalism in Canada and Canadian literature—towards a literary and political history
Creators: name: McCormack, Brendan
Publisher: name: University of British Columbia
Year: 2020

description: “Red Tiles, White Mosaic” offers a literary and political history analyzing the settler-colonial processes by which the state-driven project of multiculturalism became Canada’s distinctive, even “indigenous” national feature by settling itself on Indigenous lands. I examine multiculturalism as a politics of colonial misrecognition whose strategies of managing diversity have excluded or reframed Indigenous political difference as “cultural” difference, obfuscating Indigenous nationhood and the colonial dispossession at the formation of the multicultural nation-state. In Part 1, “Politics and Public Policy,” I historicize the “mosaic” and the development of Canadian multicultural nationalism in literary and political discourse since the nineteenth century, showing how official multiculturalism materialized as an extension of the colonial project of nation-building. Chapter 1 offers a novel and sustained historical critique of multiculturalism’s federal institutionalization since 1971 through the spheres of public policy, law, and political philosophy, mapping the strategies of Indigenous appropriation, exclusion, and containment in the architecture of liberal multiculturalism. Chapter 2 explores the ambivalent material effects of early ethnicity-oriented multicultural policy on publishing in Indigenous newsletters in the 1970s, examining the poetry in publications of the Union of BC Indian Chiefs as a case study. In Part 2, “Political Economy, Pedagogy, and Representation,” I study how the policy and ideology of multiculturalism and the state’s multicultural patronage of arts has transmuted within the Canadian literary field and inflected the reception and construction of Indigenous writing as “multicultural” literature, focusing primarily on the institution of the literary anthology. In Chapter 3, I historicize and theorize the anthology’s significance to multiculturalism’s growing visibility and institutionalization in Canadian literary studies in the 1970s and 1980s. In Chapters 4 and 5, I offer sustained close readings of the discrepant approaches to representing Indigenous literatures in two formative “multicultural” anthologies of the 1990s—Other Solitudes: Canadian Multicultural Fictions (1990) and Making a Difference: Canadian Multicultural Literature (1996)—examining how multicultural recognition obscures the expressive literary politics of Indigenous nationhood. My conclusion brings this literary and political history into the ostensibly “post-multicultural” present, arguing for the ongoing need to decolonize multicultural Canada and Canadian literary multiculturalism.
Additional file 5 of Appointment structure in Malaysian healthcare system during the COVID-19 pandemic: The public perspective
Creators: name: Subramaniam Kalianan, Ramani
name: Woon, Yuan Liang
name: Hing, Yee Liang
name: Leong, Chin Tho
name: Lim, Wei Yin
name: Loo, Ching Ee
name: Low, Lee Lan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Additional file 5. Reasons for agreeing on weekend appointments.
Ginkgo biloba leaves extract’s cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation
Creators: name: Abdellatif, Ahmed A. H.
name: Mohammed, Hamdoon A.
name: Al-Khalaf, Ali M.
name: Khan, Omar
name: Mostafa, Mahmoud A. H.
name: Al Haidari, Rwaida A.
name: Taha, Hesham H.
name: Khan, Riaz A.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Ginkgo biloba (GB) leaves extract is known to possess potent antioxidants and other bioactivities such as improved skin conditions and rejuvenation. This study aimed to develop a cosmeceutical preparation to utilize the strong antioxidant potential of GB leaves as part of the skincare formulation. Cream incorporated GB (GBC) was prepared by mixing the obtained extract with stearic acid-sodium hydroxide components in an emulsion format. The obtained GBC was characterized for GB contents, uniformity, pH, compatibility, stability, and skin’s human application. A homogeneous, physically, and chemically stable, with pH near the skin pH and shiny cream, was obtained. The prepared cream was easy to rub and pearly in appearance. It was effective and safe during the two-week trial conducted on human volunteers according to clinical trial registry protocols. The cream scavenged free radicals in DPPH assay tests. The cream incorporated GB made the skin more spirited and tauter. Furthermore, the wrinkles were reduced and the skin was renewed vigor. The GBC worked at the topical level and provided benefits when applied daily for the trial duration. The formulation also provided visually observable anti-wrinkle effects on the skin, with visible improvements in the skin’s shape and texture. The prepared cream can be used to rejuvenate the skin.
An in-vitro quantitative investigation on the synergistic effect of capsaicin and 5-fluorouracil encapsulated into lipid nanocapsules to treat breast cancer
Creators: name: Radwan, Yasmine
name: Arafa, Kholoud K.
name: Ghoniem, Monira G.
name: Al-Farraj, Eida S.
name: El-Sherbiny, Ibrahim M.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Breast cancer conventional therapeutics are effective; however, they encounter some limitations including multidrug resistance, the presence of pharmacological barriers, and non-selectivity which hinder their optimal therapeutic efficacy. Overcoming such drawbacks necessitates the development of efficient drug vehicles including lipid-based nanoparticles. This study aimed to quantitatively investigate in-vitro the synergistic therapeutic effect of the novel combination of capsaicin and 5-fluorouracil (5-FU) encapsulated in lipid nanocapsules (LNCs). To this end, thorough physicochemical and in-vitro assessments on the breast cancer cell line (MCF-7) were done. The drug-loaded LNCs were characterized using DLS, TEM imaging, stability study, and in-vitro release study. Furthermore, the biological activity of the prepared LNCs was assessed by implementing comparative cytotoxicity studies as well as apoptosis, and cell cycle flow cytometric analyses. The developed nanoformulations were monodisperse with average particle size (PS) of 31, 43.8, and 127.3 nm for empty LNCs, Cap-LNCs, and 5-FU-LNCs, respectively, and with a surface charge of −35.4, −21.7 and −31.4 mV, respectively, reflecting good physical stability. The TEM micrographs revealed the spherical morphology of the drugs-loaded LNCs with comparable PS to that obtained by DLS. on the other hand, all the biological assessments confirmed the superior antiproliferative effect of the combined drug-loaded LNCs over their free drug counterparts. Intriguingly, the study findings highlighted the potential synergistic activity of the drugs (capsaicin and 5-FU) and the extensive enhancement of their biological activity through incorporation into LNCs. Such promising results will pave the way to further novel combined nanoformulation in preclinical and clinical studies on breast cancer patients.
Additional file 6 of Appointment structure in Malaysian healthcare system during the COVID-19 pandemic: The public perspective
Creators: name: Subramaniam Kalianan, Ramani
name: Woon, Yuan Liang
name: Hing, Yee Liang
name: Leong, Chin Tho
name: Lim, Wei Yin
name: Loo, Ching Ee
name: Low, Lee Lan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Additional file 6. Reasons for disagreeing on after 5pm weekday appointments.
title: LA PIANIFICAZIONE “ANTIFRAGILE” PER IL SISTEMA DEI TRASPORTI: L’APPLICAZIONE DEL GEODESIGN COME STRUMENTO OPERATIVO
Creators: name: Acierno, Antonio
name: Lanzi, Gianluca
Publisher: name: BDC. Bollettino Del Centro Calza Bini
Year: 2018

description: Le condizioni di fragilità del territorio e l’incremento delle catastrofi (si ricorda il recente
crollo del ponte Morandi a Genova), di origine naturale ed antropica, invocano un cambio
di approccio alla pianificazione che possa convivere con le condizioni della “città panico”.
La teoria culturale del rischio di Douglas negli anni ’80 poneva l’accento sul rapporto tra
consenso sociale e sapere tecnico rivelando la necessità di integrazione delle due
componenti. La teoria dell’antifragilità che prosegue le riflessioni sul rapporto rischi/società
proposta da Taleb ed applicata ai sistemi socio economici è stata ripresa ed adattata da
Cecchini e Blečić nel campo urbanistico con l’idea della pianificazione antifragile. I
principi teorici suggeriti possono trovare nel geodesign proposto da Steinitz un valido
strumento operativo. Nel paper si avanza l’applicazione di questa proposta nel settore dei
trasporti richiamando un’interessante esperienza di interventi sui ponti stradali nell’Oregon.
Parole chiave: antifragilità, geodesign, infrastrutture dei trasporti
description: BDC. Bollettino Del Centro Calza Bini, V. 18 N. 1 (2018): Approaches and Tools for Implementing the Circular City Model
Additional file 7 of Appointment structure in Malaysian healthcare system during the COVID-19 pandemic: The public perspective
Creators: name: Subramaniam Kalianan, Ramani
name: Woon, Yuan Liang
name: Hing, Yee Liang
name: Leong, Chin Tho
name: Lim, Wei Yin
name: Loo, Ching Ee
name: Low, Lee Lan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Additional file 7. Reasons for disagreeing on weekend appointments.
Additional file 8 of Appointment structure in Malaysian healthcare system during the COVID-19 pandemic: The public perspective
Creators: name: Subramaniam Kalianan, Ramani
name: Woon, Yuan Liang
name: Hing, Yee Liang
name: Leong, Chin Tho
name: Lim, Wei Yin
name: Loo, Ching Ee
name: Low, Lee Lan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Additional file 8. Acceptance of off-office hour appointments.
Coupling of bonding and antibonding electron orbitals in double quantum dots by spin-orbit interaction
Creators: name: Nowak, M. P.
name: Szafran, B.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We perform a systematic exact diagonalization study of spin-orbit coupling effects for stationary few-electron states confined in quasi two-dimensional double quantum dots. We describe the spin-orbit-interaction induced coupling between bonding and antibonding orbitals and its consequences for magneto-optical absorption spectrum. The spin-orbit coupling for odd electron numbers (one, three) %only weakly perturbs the ground-state wave functions. %Nevertheless, %the spin-orbit interaction opens avoided crossings between low energy excited levels of opposite spin orientation and opposite spatial parity. For two-electrons the spin-orbit coupling allows for low-energy optical transitions that are otherwise forbidden by spin and parity selection rules. We demonstrate that the energies of optical transitions can be significantly increased by an in-plane electric field but only for odd electron numbers. Occupation of single-electron orbitals and effects of spin-orbit coupling on electron distribution between the dots are also discussed.
Additional file 2: of The role of podocyte damage in the etiology of ischemia-reperfusion acute kidney injury and post-injury fibrosis
Creators: name: Chen, Yi
name: Lin, Liyu
name: Tao, Xuan
name: Song, Yankun
name: Cui, Jiong
name: Wan, Jianxin
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology

description: Changes in urinary protein, BUN and Scr in each group from D0 to D7 (−x ± s, n = 10) There is no significant difference of urine protein, Scr and BUN in AKI mouse model from day 0 to day 7. (DOCX 20 kb)
title: EDITORIAL
Creators: name: Fusco Girard, Luigi
Publisher: name: Bulletin of the Calza Bini Center
Year: 2018

description: This new number of BDC takes up and deepens the theme of the circular economy as a new
urban development model.
As is generally known, this model has been introduced through the strategic goal n. 12 of
Agenda 2030 and has been recalled in its spatial interpretation in the New Urban Agenda in
paragraphs 71-74: in the circular city model.
In which way (approaches, tools) can we move towards this new urban development
strategy, reducing the consumption of all resources and thus the amount of waste? In which
way is it possible to avoid the waste/underuse of different forms of capital: natural, manmade,
human and social?
The CLIC project, financed under the HORIZON 2020 program by the European
Commission, deals with the inclusion of the reuse of cultural heritage in the context of the
circular city model.
The Interdepartmental Research Center “Alberto Calza Bini” has been particularly involved
in the identification of new evaluation processes at different scales (urban, historical
district, single site) since they are the element able to link as a “fil-rouge” both governance
strategies and the new business and financing/management models.
description: Bulletin of the Calza Bini Center, V. 18 N. 1 (2018): Approaches and Tools for Implementing the Circular City Model
Sustainable growth in complex networks
Creators: name: Tessone, Claudio J.
name: Geipel, Markus M.
name: Schweitzer, F.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: Based on the empirical analysis of the dependency network in 18 Java projects, we develop a novel model of network growth which considers both: an attachment mechanism and the addition of new nodes with a heterogeneous distribution of their initial degree, $k_0$. Empirically we find that the cumulative degree distributions of initial degrees and of the final network, follow power-law behaviors: $P(k_{0}) \propto k_{0}^{1-α}$, and $P(k)\propto k^{1-γ}$, respectively. For the total number of links as a function of the network size, we find empirically $K(N)\propto N^β$, where $β$ is (at the beginning of the network evolution) between 1.25 and 2, while converging to $\sim 1$ for large $N$. This indicates a transition from a growth regime with increasing network density towards a sustainable regime, which revents a collapse because of ever increasing dependencies. Our theoretical framework is able to predict relations between the exponents $α$, $β$, $γ$, which also link issues of software engineering and developer activity. These relations are verified by means of computer simulations and empirical investigations. They indicate that the growth of real Open Source Software networks occurs on the edge between two regimes, which are either dominated by the initial degree distribution of added nodes, or by the preferential attachment mechanism. Hence, the heterogeneous degree distribution of newly added nodes, found empirically, is essential to describe the laws of sustainable growth in networks.
description: 5 pages, 2 figures, 1 table