cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Method and apparatus for producing parts by selective sintering
Creators: name: Deckard, Carl R.
Publisher: name: United States Patent and Trademark Office
Year: 1991
Subjects: subject: B05C19/008
subject: B05C19/00
subject: B22F3/004
subject: B22F3/105
subject: B22F3/1055
subject: B22F7/02
subject: B22F2003/1052
subject: B22F2003/1056
subject: B22F2998/00
subject: B22F2998/10
subject: B22F3/26
subject: B23K26/08
subject: B23K26/082
subject: B23K26/34
subject: B29C41/12
subject: B29C41/46
subject: B29C64/153
subject: B29C35/045
subject: C23C24/08
subject: C23C24/10
subject: C23C26/02
subject: G05B19/41
subject: G05B2219/49013
subject: G05B2219/49018
subject: Y02P10/295
subject: 219/121.63
subject: 219/121.84
subject: 264/497
subject: 419/61

description: A method and apparatus for selectively sintering a layer of powder to produce a part comprising a plurality of sintered layers. The apparatus includes a computer controlling a laser to direct the laser energy onto the powder to produce a sintered mass. The computer either determines or is programmed with the boundaries of the desired cross-sectional regions of the part. For each cross-section, the aim of the laser beam is scanned over a layer of powder and the beam is switched on to sinter only the powder within the boundaries of the cross-section. Powder is applied and successive layers sintered until a completed part is formed. Preferably, the powder dispensing mechanism includes a drum which is moved horizontally across the target area and counter-rotated to smooth and distribute the powder in an even layer across the target area. A downdraft system provides controlled temperature air flow through the target area to moderate powder temperature during sintering.
Acute Arterial Stiffness Response to Anaerobic Capacity in 2 Older People: A Randomized Cross-Over Trial
Creators: name: Landim, Síbila Floriano
Publisher: name: OSF Registries
Year: 2025
Subjects: subject: Medicine and Health Sciences

description: This study investigates the acute arterial stiffness response in older individuals following anaerobic exercise. The randomized cross-over trial aims to assess how anaerobic capacity affects arterial stiffness in two elderly participants. The intervention involves an anaerobic exercise protocol, and arterial stiffness will be measured before and after the exercise sessions. The study seeks to gain a better understanding of how anaerobic exercise may impact cardiovascular health in older populations, with the goal of providing insights for improving exercise strategies in elderly individuals.
Scolopsis vosmeri Bloch 1792
Creators: name: Bogorodsky, Sergey V.
name: Alpermann, Tilman J.
name: Mal, Ahmad O.
name: Gabr, Mohamed H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Nemipteridae
Scolopsis
Scolopsis vosmeri

description: Scolopsis vosmeri (Bloch, 1792)
Material examined. SMF 35054 (2: 10.1–15.4 cm); KAUMM 103 (3: 9.8–14.8 cm).
Remarks. Trawled specimens differ from typical S. vosmeri, described from Japan, in lacking of a whitish stripe anteriorly on the side of the body below lateral line. Probably, S. vosmeri is a complex of similar species, and at present under study by Barry C. Russell. If the Red Sea population is re-instated as a separate species, the name Scolopsis kurite Rüppell, 1828 would be available.
description: Published as part of Bogorodsky, Sergey V., Alpermann, Tilman J., Mal, Ahmad O. & Gabr, Mohamed H., 2014, Survey of demersal fishes from southern Saudi Arabia, with five new records for the Red Sea, pp. 401-437 in Zootaxa 3852 (4) on page 426, DOI: 10.11646/zootaxa.3852.4.1, http://zenodo.org/record/225360
Orion
Creators: name: Blasi, Matthew Brandon
Publisher: name: No Publisher Supplied
Year: 2010

description: Orion is the story of Iraq war vet Gene Temmens as he returns home to Michigan in an attempt to reconnect with family and start over.  But when financial crises rear their heads and smoothing out the wrinkles in his family relationships proves almost impossible, Gene lapses into old habits that end in murder.
Parupeneus forsskali Fourmanoir & Gueze 1976
Creators: name: Bogorodsky, Sergey V.
name: Alpermann, Tilman J.
name: Mal, Ahmad O.
name: Gabr, Mohamed H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Mullidae
Parupeneus
Parupeneus forsskali

description: Parupeneus forsskali (Fourmanoir & Guézé, 1976)
Material examined. SMF 34971 (1: 16.6 cm).
description: Published as part of Bogorodsky, Sergey V., Alpermann, Tilman J., Mal, Ahmad O. & Gabr, Mohamed H., 2014, Survey of demersal fishes from southern Saudi Arabia, with five new records for the Red Sea, pp. 401-437 in Zootaxa 3852 (4) on page 426, DOI: 10.11646/zootaxa.3852.4.1, http://zenodo.org/record/225360
Additional file 1: of A systematic review protocol on the effectiveness of therapeutic exercises utilised by physiotherapists to improve function in patients with burns
Creators: name: Tapfuma Mudawarima
name: Chiwaridzo, Matthew
name: Jelsma, Jennifer
name: Grimmer, Karen
name: Muchemwa, Faith
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology

description: PRISMA-P 2015 Checklist. (DOCX 34Â kb)
title: Aerosol jet etching
Creators: name: Brock, James R.
name: Trachtenberg, Isaac
Publisher: name: United States Patent and Trademark Office
Year: 1991
Subjects: subject: C23F1/12
subject: C23F1/08
subject: 252/79.1
subject: 438/748

description: A device and method for etching a body are provided capable of etching fine geometry patterns utilizing the high selectivity of wet etching and the anisotropic etch characteristics of dry etching. The body to be etched is placed in a reduced pressure etching chamber. An inert carrier gas is bubbled through heated liquid etchant producing a vapor stream of liquid etchant. A non-reactive gas is chilled producing a cold gas stream. The vapor stream and the cold gas stream are combined in an aerosol generation nozzle producing a high concentration of fine aerosol particles by homogeneous nucleation. The fine aerosol particles enter an aerosol growth chamber and form larger particles through thermal coagulation. The larger particles are accelerated out of the growth chamber through an expansion nozzle positioned within the reduced pressure etching chamber and directed toward the body to be etched. This aerosol jet of etchant impacts the surface of the body to be etched. The small size of these larger particles allows for etching fine geometry patterns. Additionally, aerosol jet etching avoids the need to rinse the body after being etched as required in wet etching to halt the etching process.
Rapid mortality in captive bush dogs (Speothos venaticus) caused by influenza A of avian origin (H5N1) at a wildlife collection in the United Kingdom
Creators: name: Falchieri, Marco
name: Reid, Scott M.
name: Dastderji, Akbar
name: Cracknell, Jonathan
name: Warren, Caroline J.
name: Mollett, Benjamin C.
name: Peers-Dent, Jacob
name: Schlachter, Audra-Lynne D
name: Mcginn, Natalie
name: Hepple, Richard
name: Thomas, Saumya
name: Ridout, Susan
name: Quayle, Jen
name: Pizzi, Romain
name: Núñez, Alejandro
name: Byrne, Alexander M. P.
name: James, Joe
name: Banyard, Ashley C.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Europe has suffered unprecedented epizootics of high pathogenicity avian influenza (HPAI) clade 2.3.4.4b H5N1 since Autumn 2021. As well as impacting upon commercial and wild avian species, the virus has also infected mammalian species more than ever observed previously. Mammalian species involved in spill over events have primarily been scavenging terrestrial carnivores and farmed mammalian species although marine mammals have also been affected. Alongside reports of detections in mammalian species found dead through different surveillance schemes, several mass mortality events have been reported in farmed and wild animals. During November 2022, an unusual mortality event was reported in captive bush dogs (Speothos venaticus) with clade 2.3.4.4b H5N1 HPAIV of avian origin being the causative agent. The event involved an enclosure of fifteen bush dogs, ten of which succumbed during a nine-day period with some dogs exhibiting neurological disease. Ingestion of infected meat is proposed as the most likely infection route.
Upeneus guttatus Day 1868
Creators: name: Bogorodsky, Sergey V.
name: Alpermann, Tilman J.
name: Mal, Ahmad O.
name: Gabr, Mohamed H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Mullidae
Upeneus
Upeneus guttatus

description: Upeneus guttatus (Day, 1868)
Material examined. SMF 35012 (1: 7.9 cm).
description: Published as part of Bogorodsky, Sergey V., Alpermann, Tilman J., Mal, Ahmad O. & Gabr, Mohamed H., 2014, Survey of demersal fishes from southern Saudi Arabia, with five new records for the Red Sea, pp. 401-437 in Zootaxa 3852 (4) on page 426, DOI: 10.11646/zootaxa.3852.4.1, http://zenodo.org/record/225360
HLA-mismatched allogeneic adoptive immune therapy in patients with severely immunosuppressed AIDS: a multicenter, open-label, controlled, phase 2a study
Creators: name: Yang, Tao
name: Xie, Zhiman
name: Xu, Zhe
name: Tu, Bo
name: Lu, Huan
name: Huang, Huihuang
name: Huang, Lei
name: Zhang, Chao
name: Gao, Liying
name: Jin, Lei
name: Ma, Ping
name: Zou, Jun
name: Liu, Limin
name: Zhen, Cheng
name: Zhou, Chunbao
name: Meng, Sirun
name: Li, Yuan-Yuan
name: Song, Jin-Wen
name: Yang, Shixiong
name: Ai, Hui-Sheng
name: Jiao, Yanmei
name: Shi, Ming
name: Xu, Ruonan
name: Wang, Fu-Sheng
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Recurrent opportunistic infections (OIs) in patients with severely immunosuppressed AIDS remain an unresolved medical challenge despite advancements in antiretroviral therapy (ART). To address this gap, we developed an HLA-mismatched allogeneic adoptive immune therapy (AAIT) specifically targeting this patient population. The safety and efficacy of this novel therapeutic approach were preliminarily confirmed in our phase 1 trial. Subsequently, a multicenter, open-label, controlled, phase 2a trial was conducted to evaluate the efficacy of AAIT in combination with ART compared with the conventional ART-only regimen. No difference in the incidence of adverse events (AEs) was observed between the two groups at the 96-week follow-up. AAIT treatment improved CD4+ T cell recovery at weeks 72 (P = 0.048) and 96 (P = 0.024) compared to the Control Group. Additionally, stratified analysis of patients in the AAIT Group showed that donor/recipient sex mismatch was significantly associated with the likelihood of patients achieving an immunological response (OR = 8.667; 95% CI, 2.010–37.377; P = 0.004). These findings suggest that AAIT serves as a promising adjunct therapy for improving the outcomes of patients with severely immunosuppressed AIDS. Further studies are needed to elucidate the immunological mechanisms underlying AAIT and identify the subpopulations that respond optimally to this therapeutic approach. This trial is registered at www.clinicaltrials.gov (NCT04098770). Trial registration:ClinicalTrials.gov identifier: NCT04098770. Trial registration:ClinicalTrials.gov identifier: NCT02651376.
title: Mononuclear and multinuclear phosphido, arsenido, and stibido complexes of aluminum, gallium and indium
Creators: name: Jones, Richard A.
name: Cowley, Alan H.
name: Ekerdt, John G.
Publisher: name: United States Patent and Trademark Office
Year: 1991
Subjects: subject: C07F9/28
subject: C07F9/70
subject: C07F9/90
subject: C23C16/301
subject: 556/19
subject: 556/20
subject: 556/30
subject: 556/176

description:  The present invention involves chemical compounds particularly useful for the preparation of thin films or layers of group 3/group 5 materials by MOCVD and other techniques. Such compounds may be represented as having the formulas [M(ER'R").sub.3 ].sub.n or [RM(ER'R").sub.2 ].sub.n or [R.sub.2 M(ER'R")].sub.n wherein M is aluminum, gallium or indium; E is phosphorus, arsenic or antimony; R, R', and R" are one or more of hydrogen, alkyl, aryl, alkyl-substituted aryl, cyclic alkyl, halide or other anionic group; and n is between about 1 and about 6.
TEACHER JOB SATISFACTION AND LEADERSHIP STYLES: INSIGHTS FROM PUBLIC BASIC SCHOOLS IN GHANA
Creators: name: Samuel, Kwame Asante
Publisher: name: kEITH jOURNAL
Year: 2025
Subjects: Quality Teaching, Educational Leadership, School Effectiveness, Pedagogical Enhancement, Sub-Saharan Africa

description: The global landscape of education underscores the paramount importance of quality teaching as an indispensable catalyst for effective and efficient learning within school systems. The deliberate establishment of schools is rooted in the pursuit of specific educational goals, necessitating a robust commitment to ensuring quality teaching and learning. The onus often falls on school managers and administrators to orchestrate an environment conducive to achieving these educational objectives. Central to this mission is the acknowledgment that the quality of teaching and learning is intricately tied to the allocation of human and material resources within schools, as emphasized by Armstrong (2006). However, a critical analysis of existing literature reveals a persistent challenge in Sub-Saharan African schools, where the dearth of quality leaders hampers the realization of optimal teaching and learning environments (Adeyemi and Bolarinwa, 2013; Oino and Asghar, 2018). Leadership emerges as a crucial determinant in the effective utilization of scarce educational resources, guiding schools towards their envisioned goals and objectives, as posited by Suryani (2018). Recognizing the pivotal role of leadership, it becomes imperative to view it not merely as an administrative duty but as a transformative force capable of enhancing teachers' pedagogical skills and fostering a motivating learning environment for students. Numerous scholars, including Lumbantoruan et al. (2020) and Sayadi (2016), assert that effective leadership is a linchpin in determining a school's overall effectiveness. These abstract aims to delve into the critical nexus between leadership, pedagogical enhancement, and student motivation in the context of Sub-Saharan African schools. By synthesizing insights from diverse scholarly perspectives, the study seeks to illuminate the multifaceted role of leadership in shaping the quality of teaching and learning, thus contributing to the broader discourse on educational leadership and its impact on school effectiveness
title: Miniature railgun engine ignitor
Creators: name: Weldon, William F.
name: Matthews, Ronald D.
name: Harden, Brian L.
name: Nichols, Steven P.
Publisher: name: United States Patent and Trademark Office
Year: 1991
Subjects: subject: F02P9/007
subject: F02B2275/14
subject: H01T13/50
subject: Y02T10/123
subject: 123/143B
subject: 313/143

description: A plasma ignitor system capable of injection a narrowly focused high energy plasma jet into a combustion chamber of an internal combustion engine or continuous combustion system. The plasma ignitor features a high energy current pulse source and a geometrically configured coaxial or dual-rail ignitor system for deeper and more accurate injection of plasma into a combustion chamber of either large or small dimension.
The joy of giving
Creators: name: Brand, Tina M.
Publisher: name: No Publisher Supplied
Year: 2010

description: This research aims to further our knowledge about why people donate money to charity.  I hypothesized that fundraising requests that were a) handwritten, and b) contained  positive emotion words related to pro-social motivations would increase donations  relative to requests that lacked these qualities. Participants were drawn from the mailing  list of a local charitable organization that conducts a yearly direct mail fundraising  campaign. Participants were randomly assigned to one of five conditions: 1) Only the  standard fundraising packet (standard), 2) standard plus a printed note with positive  emotion words, 3) standard plus a handwritten note with positive emotion words, 4)  standard plus a printed note without positive emotion words, 5) standard plus a  handwritten note without positive emotion words. The results indicated that those who  received a handwritten letter donated more money; positive emotion words did not seem  to have an effect. These findings can help charitable organizations design and enhance  their campaign strategies.
A novel BSL-2 Lassa virus reverse genetics system modelling the complete viral life cycle
Creators: name: Hu, Xiaoyou
name: Bai, Xu
name: Tian, Fangling
name: Xing, Yifan
name: Shi, Yi
name: Tong, Yimin
name: Zhong, Jin
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Lassa virus (LASV), a risk-group 4 pathogen, must be handled in biosafety level-4 (BSL-4) conditions, thereby limiting its research and antiviral development. Here, we developed a novel LASV reverse genetics system which, to our knowledge, is the first to study the complete LASV life cycle under BSL-2 conditions. Viral particles can be produced efficiently when LASV minigenomic RNA harbouring minimal viral cis-elements and reporter genes is transfected into a helper cell line stably expressing viral NP, GP, Z and L proteins. The resulting defective virions, named LASVmg, can propagate only in the helper cell line, providing a BSL-2 model to study the complete LASV life cycle. Using this model, we found that a previously reported cellular receptor α-dystroglycan is dispensable for LASVmg infection. Furthermore, we showed that ribavirin can inhibit LASVmg infection by inducing viral mutations. This new BSL-2 system should facilitate studying the LASV life cycle and screening antivirals.
Experimental co-infection of calves with SARS-CoV-2 Delta and Omicron variants of concern
Creators: name: Cool, Konner
name: Gaudreault, Natasha N.
name: Trujillo, Jessie D.
name: Morozov, Igor
name: McDowell, Chester D.
name: Bold, Dashzeveg
name: Kwon, Taeyong
name: Balaraman, Velmurugan
name: Assato, Patricia
name: Madden, Daniel W.
name: Mantlo, Emily
name: Souza-Neto, Jayme
name: Matias-Ferreyra, Franco
name: Retallick, Jaime
name: Singh, Gagandeep
name: Schotsaert, Michael
name: Carossino, Mariano
name: Balasuriya, Udeni B. R.
name: Wilson, William C.
name: Pogranichniy, Roman M.
name: García-Sastre, Adolfo
name: Richt, Juergen A.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Since emerging in late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has repeatedly crossed the species barrier with natural infections reported in various domestic and wild animal species. The emergence and global spread of SARS-CoV-2 variants of concern (VOCs) has expanded the range of susceptible host species. Previous experimental infection studies in cattle using Wuhan-like SARS-CoV-2 isolates suggested that cattle were not likely amplifying hosts for SARS-CoV-2. However, SARS-CoV-2 sero- and RNA-positive cattle have since been identified in Europe, India, and Africa. Here, we investigated the susceptibility and transmission of the Delta and Omicron SARS-CoV-2 VOCs in cattle. Eight Holstein calves were co-infected orally and intranasally with a mixed inoculum of SARS-CoV-2 VOCs Delta and Omicron BA.2. Twenty-four hours post-challenge, two sentinel calves were introduced to evaluate virus transmission. The co-infection resulted in a high proportion of calves shedding SARS-CoV-2 RNA at 1- and 2-days post-challenge (DPC). Extensive tissue distribution of SARS-CoV-2 RNA was observed at 3 and 7 DPC and infectious virus was recovered from two calves at 3 DPC. Next-generation sequencing revealed that only the SARS-CoV-2 Delta variant was detected in clinical samples and tissues. Similar to previous experimental infection studies in cattle, we observed only limited seroconversion and no clear evidence of transmission to sentinel calves. Together, our findings suggest that cattle are more permissive to infection with SARS-CoV-2 Delta than Omicron BA.2 and Wuhan-like isolates but, in the absence of horizontal transmission, are not likely to be reservoir hosts for currently circulating SARS-CoV-2 variants.
title: Sublimating and cracking apparatus
Creators: name: Streetman, Ben G.
name: Mattord, Terry J.
name: Neikirk, Dean P.
Publisher: name: United States Patent and Trademark Office
Year: 1992
Subjects: subject: C23C14/243
subject: C30B23/06
subject: Y10S148/006
subject: Y10S148/169
subject: Y10S438/935
subject: 118/715
subject: 118/724
subject: 118/726
subject: 148/DIG6
subject: 148/DIG169
subject: 156/103
subject: 422/164
subject: 422/167
subject: 422/199
subject: 438/935

description: A furnace having a sublimating section, a cracking section oriented off axis to the sublimating section, and a valve for controlling flux between the sections. The valve includes an annular plug having at least one longitudinal slot. The plug is retractable from a fully closed position where the slot is completely covered, to a fully open position where the slot is completely exposed. The slot becomes increasingly exposed as the plug is moved from the fully closed position to the fully opened position, thereby increasing flux from the sublimating section to the cracking section.
Can You Dig It?  The ethics and politics of cultural property
Creators: name: DelColle, Jeanne M.
Publisher: name: No Publisher Supplied
Year: 2010

description: Can You Dig It? is a little archaeology humor that is meant to serve a dual purpose.  It is meant as both a literal question and as colloquial slang.  The first section of this paper focuses on the politics of cultural property.   The question, Can You Dig It?, literally asks if items of cultural property can be excavated, by whom, and if they may leave their country of origin.  To address these issues, there has been legislation, both international and national, to help regulate the flow of cultural property and prevent the terrible damage done by theft and looting. The second section of Can You Dig It? focuses on the colloquial slang and presents to readers information to allow a basic comprehension of the issues central to the debate of cultural property.  While legislation may seem very straightforward, archaeologists, nation-states, museums, and collectors all assign a different type of value to objects and so do not agree on the best practices and uses for cultural property.   The pros and cons of each are presented to readers for their consideration, and the ethics of cultural property are discussed. In the final section, possible solutions to the debate are proposed.  These include a type of public service campaign for archaeologists to reach out to communities both at home and abroad.   This outreach has already included the education of the U.S. military, particularly those being deployed to Iraq and Afghanistan, about the cultural heritage of the Middle East.  Finally, a push to extend archaeology education to teachers and, by extension, their students in the public school system could result in discouraging the next generation of looters.
title: Photodynamic activity of sapphyrins
Creators: name: Harriman, Anthony M.
name: Sessler, Jonathan L.
name: Maiya, Bhaskar G.
Publisher: name: United States Patent and Trademark Office
Year: 1992
Subjects: subject: A61K41/0076
subject: C01B13/02
subject: 204/157.15
subject: 204/157.61

description: The present invention includes a method to produce singlet oxygen from molecular oxygen generated by reaction with a sapphyrin compound excited at an absorbing wavelength to form a triplet species. Specifically, the sapphyrin compound is an alkylated sapphyrin, most preferably diprotonated 3,8,12,13,17,22-hexaethyl-2,7,18,23-tetramethylsapphyrin. Generation of the triplet species may be accomplished in an organic solvent, of which the most preferable solvents are chloroform, methanol or acetonitrile. Also encompassed within the present invention is a method to selectively produce singlet oxygen in an aqueous environment. A sapphyrin compound is incorporated within a membranous vesicle, the vesicle is illuminated with exciting light and the resultant excited triplet state sapphyrin compound reacts with molecular oxygen to produce singlet oxygen. Singlet oxygen was not generated external to the vesicle where the sapphyrin compound is present in an aqueous medium.
Upeneus heemstra Uiblein & Gouws 2014
Creators: name: Bogorodsky, Sergey V.
name: Alpermann, Tilman J.
name: Mal, Ahmad O.
name: Gabr, Mohamed H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Mullidae
Upeneus
Upeneus heemstra

description: Upeneus heemstra Uiblein & Gouws, 2014
Material examined. SMF 35056 (2: 12.1–12.3 cm); SMF 35061 (5: 12.9–14.4 cm); KAUMM 106 (2: 11.4–12.7cm); KAUMM 110 (4: 11.7–14.6 cm).
description: Published as part of Bogorodsky, Sergey V., Alpermann, Tilman J., Mal, Ahmad O. & Gabr, Mohamed H., 2014, Survey of demersal fishes from southern Saudi Arabia, with five new records for the Red Sea, pp. 401-437 in Zootaxa 3852 (4) on page 427, DOI: 10.11646/zootaxa.3852.4.1, http://zenodo.org/record/225360
title: Railguns with current guard plates
Creators: name: Weldon, William F.
name: Beno, Joseph H.
Publisher: name: United States Patent and Trademark Office
Year: 1992
Subjects: subject: F41B6/006
subject: 124/3
subject: 89/8

description: An electromagnetic projectile launcher or railgun capable of withstanding hundreds or thousands of shots. The railgun features a current management system having guard plates which act to reduce peak rail current densities while also maximizing projectile velocity. Guard plates can be used in either square or round bore designs and can be powered by either a single or separate power supply from that of the rails.
Positive feedback regulation of wishful thinking shapes bone morphogenetic protein signaling in the follicular epithelium
Creators: name: Marmion, Robert
Publisher: name: No Publisher Supplied
Year: 2010

description: Morphogenesis is preceded by an extensive gene patterning that is regulated by a  small number of signaling pathways. One such pathway, the Bone Morphogenetic  Protein (BMP) pathway, is an essential developmental regulator in many organisms  throughout Eukarya, including Drosophila melanogaster. An established system to study  patterning that is regulated by cell-to-cell signaling is D. melanogaster oogenesis. A  two-dimensional monolayer of follicle cells (FCs) surrounds the developing oocyte,  becomes patterned and later folds into eggshell structures; this process is regulated, in  part, by BMP signaling. While BMP signaling in the FCs is associated with the patterning  of the type I receptor, thickveins (tkv), the cooperating type II receptor remains unknown.  Here, I aimed to establish its identity. Though previously only reported during  embryonic neurogenesis, I found that the type II receptor, wishful thinking (wit), is  expressed in an evolutionary conserved pattern in the FCs of species that diverged over  45 million years. Also, WIT is self-regulated by a positive feedback loop, which I  demonstrate works to sharpen the BMP signaling gradient. Of importance, null clones of  WIT coincide with a cell autonomous loss of BMP signaling, monitored by the phosphorylated form of the intercellular signaling molecule MAD (P-MAD). Loss of WIT has changes the patterning of Broad, a marker for dorsal appendages, affecting eggshell morphology. These results demonstrate an active role for WIT in non-neuronal tissue, and establish WIT as the type II receptor working in concert with TKV during FC patterning.
Leaderless foot-and-mouth disease virus serotype O did not cause clinical disease and failed to establish a persistent infection in cattle
Creators: name: Litz, Benedikt
name: Sehl-Ewert, Julia
name: Breithaupt, Angele
name: Landmesser, Anja
name: Pfaff, Florian
name: Romey, Aurore
name: Blaise-Boisseau, Sandra
name: Beer, Martin
name: Eschbaumer, Michael
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: The foot-and-mouth disease virus (FMDV) Leader proteinase Lpro inhibits host mRNA translation and blocks the interferon response which promotes viral survival. Lpro is not required for viral replication in vitro but serotype A FMDV lacking Lpro has been shown to be attenuated in cattle and pigs. However, it is not known, whether leaderless viruses can cause persistent infection in vivo after simulated natural infection and whether the attenuated phenotype is the same in other serotypes. We have generated a FMDV O/FRA/1/2001 variant lacking most of the Lpro coding region (ΔLb). Cattle were inoculated intranasopharyngeally and observed for 35 days to determine if O FRA/1/2001 ΔLb is attenuated during the acute phase of infection and whether it can maintain a persistent infection in the upper respiratory tract. We found that although this leaderless virus can replicate in vitro in different cell lines, it is unable to establish an acute infection with vesicular lesions and viral shedding nor is it able to persistently infect bovine pharyngeal tissues.
AMXT-1501 targets membrane phospholipids against Gram-positive and -negative multidrug-resistant bacteria
Creators: name: Zheng, Jinxin
name: Liu, Xiaoju
name: Xiong, Yanpeng
name: Meng, Qingyin
name: Li, Peiyu
name: Zhang, Fan
name: Liu, Xiaoming
name: Lin, Zhiwei
name: Deng, Qiwen
name: Wen, Zewen
name: Yu, Zhijian
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: The rapid proliferation of multidrug-resistant (MDR) bacterial pathogens poses a serious threat to healthcare worldwide. Carbapenem-resistant (CR) Enterobacteriaceae, which have near-universal resistance to available antimicrobials, represent a particularly concerning issue. Herein, we report the identification of AMXT-1501, a polyamine transport system inhibitor with antibacterial activity against Gram-positive and -negative MDR bacteria. We observed minimum inhibitory concentration (MIC)50/MIC90 values for AMXT-1501 in the range of 3.13–12.5 μM (2.24–8.93 μg /mL), including for methicillin-resistant Staphylococcus aureus (MRSA), CR Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. AMXT-1501 was more effective against MRSA and CR E. coli than vancomycin and tigecycline, respectively. Subinhibitory concentrations of AMXT-1501 reduced the biofilm formation of S. aureus and Enterococcus faecalis. Mechanistically, AMXT-1501 exposure damaged microbial membranes and increased membrane permeability and membrane potential by binding to cardiolipin (CL) and phosphatidylglycerol (PG). Importantly, AMXT-1501 pressure did not induce resistance readily in the tested pathogens.
Experimental co-infection of calves with SARS-CoV-2 Delta and Omicron variants of concern
Creators: name: Cool, Konner
name: Gaudreault, Natasha N.
name: Trujillo, Jessie D.
name: Morozov, Igor
name: McDowell, Chester D.
name: Bold, Dashzeveg
name: Kwon, Taeyong
name: Balaraman, Velmurugan
name: Assato, Patricia
name: Madden, Daniel W.
name: Mantlo, Emily
name: Souza-Neto, Jayme
name: Matias-Ferreyra, Franco
name: Retallick, Jaime
name: Singh, Gagandeep
name: Schotsaert, Michael
name: Carossino, Mariano
name: Balasuriya, Udeni B. R.
name: Wilson, William C.
name: Pogranichniy, Roman M.
name: García-Sastre, Adolfo
name: Richt, Juergen A.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Since emerging in late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has repeatedly crossed the species barrier with natural infections reported in various domestic and wild animal species. The emergence and global spread of SARS-CoV-2 variants of concern (VOCs) has expanded the range of susceptible host species. Previous experimental infection studies in cattle using Wuhan-like SARS-CoV-2 isolates suggested that cattle were not likely amplifying hosts for SARS-CoV-2. However, SARS-CoV-2 sero- and RNA-positive cattle have since been identified in Europe, India, and Africa. Here, we investigated the susceptibility and transmission of the Delta and Omicron SARS-CoV-2 VOCs in cattle. Eight Holstein calves were co-infected orally and intranasally with a mixed inoculum of SARS-CoV-2 VOCs Delta and Omicron BA.2. Twenty-four hours post-challenge, two sentinel calves were introduced to evaluate virus transmission. The co-infection resulted in a high proportion of calves shedding SARS-CoV-2 RNA at 1- and 2-days post-challenge (DPC). Extensive tissue distribution of SARS-CoV-2 RNA was observed at 3 and 7 DPC and infectious virus was recovered from two calves at 3 DPC. Next-generation sequencing revealed that only the SARS-CoV-2 Delta variant was detected in clinical samples or tissues. Similar to previous experimental infection studies in cattle, we observed only limited seroconversion and no clear evidence of transmission to sentinel calves. Together, our findings suggest that cattle are more permissive to infection with SARS-CoV-2 Delta than Omicron BA.2 and Wuhan-like isolates but, in the absence of horizontal transmission, are not likely to be reservoir hosts for currently circulating SARS-CoV-2 variants.
A pan-orthoebolavirus neutralizing antibody encoded by mRNA effectively prevents virus infection
Creators: name: Fan, Pengfei
name: Sun, Bingjie
name: Liu, Zixuan
name: Fang, Ting
name: Ren, Yi
name: Zhao, Xiaofan
name: Song, Zhenwei
name: Yang, Yilong
name: Li, Jianmin
name: Yu, Changming
name: Chen, Wei
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Orthoebolavirus is a genus of hazardous pathogens that has caused over 30 outbreaks. However, currently approved therapies are limited in scope, as they are only effective against the Ebola virus and lack cross-protection against other orthoebolaviruses. Here, we demonstrate that a previously isolated human-derived antibody, 2G1, can recognize the glycoprotein (GP) of every orthoebolavirus species. The cryo-electron microscopy structure of 2G1 Fab in complex with the GPΔMucin trimer reveals that 2G1 binds a quaternary pocket formed by three subunits from two GP protomers. 2G1 recognizes highly conserved epitopes among filoviruses and achieves neutralization by blocking GP proteolysis. We designed an efficient mRNA module capable of producing test antibodies at expression levels exceeding 1500 ng/mL in vitro. The lipid nanoparticle (LNP)-encapsulated mRNA-2G1 exhibited potent neutralizing activities against the HIV-pseudotyped Ebola and Sudan viruses that were 19.8 and 12.5 times that of IgG format, respectively. In mice, the antibodies encoded by the mRNA-2G1-LNP peaked within 24 h, effectively blocking the invasion of pseudoviruses with no apparent liver toxicity. This study suggests that the 2G1 antibody and its mRNA formulation represent promising candidate interventions for orthoebolavirus disease, and it provides an efficient mRNA framework applicable to antibody-based therapies.
title: Current limiting device for overcurrent protection
Creators: name: Weldon, William F.
name: Woodson, Herbert H.
Publisher: name: United States Patent and Trademark Office
Year: 1983
Subjects: subject: H02H9/02
subject: 361/43
subject: 361/58
subject: 361/93.9
subject: 361/111

description: A current limiting device for use with a circuit breaker in an electric power system utilizes mutual inductance variation between movable windings to limit current to safe levels. In the device, first and second coil windings are electrically connected for current flow therethrough and magnetically linked for mutual inductive coupling. The effective inductance of the connected coil windings is functionally related to the relative physical positioning of the coil windings. The coil windings are movable relative to one another, so as to provide for variation in the effective inductance of the two coils. Structure is provided for disposing the coils in an initial relative positioning, the structure being yieldable to a force produced between the coils due to a predetermined magnitude of current flow through the coils. The force produced between the coils acts to change the relative positioning of the coils, increasing the effective inductance, and thereby limiting the current therethrough. In an alternative arrangement, movement of the coils to designated positions of relative placement due to a predetermined magnitude of current flow therethrough may be utilized to open a set of electrical contacts or to trigger a conventional circuit breaker interrupting the circuit.
title: Sublimating and cracking apparatus
Creators: name: Streetman, Ben G.
name: Mattord, Terry J.
name: Farley, Craig W.
Publisher: name: United States Patent and Trademark Office
Year: 1992
Subjects: subject: C23C14/243
subject: C30B23/06
subject: C30B23/066
subject: 117/108
subject: 118/715
subject: 118/724
subject: 118/726
subject: 422/129
subject: 422/109
subject: 422/164
subject: 422/167
subject: 422/199

description: A sublimating and cracking device which may be used to produce a collimated beam of molecules from a solid source. The device includes an elongated sublimating tube and an elongated cracking tube adapted to be axially oriented off axis to each other. The sublimating and cracking tubes are interconnected and heated in use.
title: Sapphyrins, derivatives and syntheses
Creators: name: Sessler, Jonathan L.
name: Cyr, Michael John
Publisher: name: United States Patent and Trademark Office
Year: 1992
Subjects: subject: A61K41/0076
subject: A61K47/54
subject: A61K47/546
subject: A61K47/558
subject: C07D487/22
subject: C07H15/26
subject: C07H21/00
subject: C12N15/101
subject: 534/15
subject: 540/465
subject: 540/467
subject: 540/470

description: The present invention involves, in addition to many unique substituted sapphyrins, a novel method for synthesizing sapphyrins with good efficiency and high yield. An improved 9-step synthesis of substituted sapphyrins, e.g., the two C.sub.2 symmetric sapphyrins, compounds 2 and 4 of FIG. 1C, is described herein. This synthesis involves as an important step the condensation between a tripyrrane diacid and a diformyl bipyrrole. The key tripyrrane component is prepared in three high-yield steps from readily available pyrrolic precursors and the bipyrrole portion is prepared in four steps from ethyl 3-methyl-4-methylpyrrole-2-carboxylate in roughly 33% yield overall.
Olgia Mikhalevich 2011
Creators: name: Mamo, Briony L.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Crabronidae
Olgia

description: Olgia Mikhalevich 2011
Olgia pacifica (Cushman 1924) (Fig. 5:9–11)
Description. See Cushman (1924; p. 22, pl. 6, figs 7–11).
Distribtuion within study area. Olgia pacifica (Cushman 1924) only ever occurs in very low numbers (one to two specimens per site) in lagoons across all four of the studied reefs.
description: Published as part of Mamo, Briony L., 2016, Benthic Foraminifera from the Capricorn Group, Great Barrier Reef, Australia, pp. 1-123 in Zootaxa 4215 (1) on pages 21-23, DOI: 10.11646/zootaxa.4215.1.1, http://zenodo.org/record/272923
Upeneus margarethae Uiblein & Heemstra 2010
Creators: name: Bogorodsky, Sergey V.
name: Alpermann, Tilman J.
name: Mal, Ahmad O.
name: Gabr, Mohamed H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Mullidae
Upeneus
Upeneus margarethae

description: Upeneus margarethae Uiblein & Heemstra, 2010
Material examined. SMF 34972 (4: 9.2–11.1 cm); SMF 35011 (3: 8.8–11.6 cm); SMF 35059 (10: 6.5–8.9 cm); SMF 35060 (1: 9.4 cm); KAUMM 27 (1: 9.2 cm); KAUMM 49 (5: 9.5–11.1 cm); KAUMM 59 (5: 8.6–10.6 cm); KAUMM 109 (11: 6.2–9.1 cm).
description: Published as part of Bogorodsky, Sergey V., Alpermann, Tilman J., Mal, Ahmad O. & Gabr, Mohamed H., 2014, Survey of demersal fishes from southern Saudi Arabia, with five new records for the Red Sea, pp. 401-437 in Zootaxa 3852 (4) on page 427, DOI: 10.11646/zootaxa.3852.4.1, http://zenodo.org/record/225360
Structural diversity of tick-borne encephalitis virus particles in the inactivated vaccine based on strain Sofjin
Creators: name: Moiseenko, Andrey
name: Zhang, Yichen
name: Vorovitch, Mikhail F.
name: Ivanova, Alla L.
name: Liu, Zheng
name: Osolodkin, Dmitry I.
name: Egorov, Alexey M.
name: Ishmukhametov, Aydar A.
name: Sokolova, Olga S.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: The main approach to preventing tick-borne encephalitis (TBE) is vaccination. Formaldehyde-inactivated TBE vaccines have a proven record of safety and efficiency but have never been characterized structurally with atomic resolution. We report a cryoelectron microscopy (cryo-EM) structure of the formaldehyde-inactivated TBE virus (TBEV) of Sofjin-Chumakov strain representing the Far-Eastern subtype. A 3.8 Å resolution reconstruction reveals the structural integrity of the envelope E proteins, specifically the E protein ectodomains. The comparative study shows a high structural similarity to the previously published structures of the TBEV European subtype strains Hypr and Kuutsalo-14. A fraction of inactivated virions exhibits asymmetric features including the deformations of the membrane profile. We propose that the heterogeneity is caused by inactivation and perform a local variability analysis on the small parts of the envelope protein shell to reveal membrane curvature features possibly induced by the inactivation. The results of this study will have implications for the design of novel vaccines against diseases caused by flaviviruses.
Upeneus moluccensis Bleeker 1855
Creators: name: Bogorodsky, Sergey V.
name: Alpermann, Tilman J.
name: Mal, Ahmad O.
name: Gabr, Mohamed H.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Mullidae
Upeneus
Upeneus moluccensis

description: Upeneus moluccensis (Bleeker, 1855)
Material examined. SMF 35055 (7: 9.1–11.0 cm); KAUMM 105 (7: 9.6–11.4 cm).
description: Published as part of Bogorodsky, Sergey V., Alpermann, Tilman J., Mal, Ahmad O. & Gabr, Mohamed H., 2014, Survey of demersal fishes from southern Saudi Arabia, with five new records for the Red Sea, pp. 401-437 in Zootaxa 3852 (4) on page 427, DOI: 10.11646/zootaxa.3852.4.1, http://zenodo.org/record/225360
Pigs are highly susceptible to but do not transmit mink-derived highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b
Creators: name: Kwon, Taeyong
name: Trujillo, Jessie D.
name: Carossino, Mariano
name: Lyoo, Eu Lim
name: McDowell, Chester D.
name: Cool, Konner
name: Matias-Ferreyra, Franco S.
name: Jeevan, Trushar
name: Morozov, Igor
name: Gaudreault, Natasha N.
name: Balasuriya, Udeni B.R.
name: Webby, Richard J.
name: Osterrieder, Nikolaus
name: Richt, Juergen A.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Rapid evolution of highly pathogenic avian influenza viruses (HPAIVs) is driven by antigenic drift but also by reassortment, which might result in robust replication in and transmission to mammals. Recently, spillover of clade 2.3.4.4b HPAIV to mammals including humans, and their transmission between mammalian species has been reported. This study aimed to evaluate the pathogenicity and transmissibility of a mink-derived clade 2.3.4.4b H5N1 HPAIV isolate from Spain in pigs. Experimental infection caused interstitial pneumonia with necrotizing bronchiolitis with high titers of virus present in the lower respiratory tract and 100% seroconversion. Infected pigs shed limited amount of virus, and importantly, there was no transmission to contact pigs. Notably, critical mammalian-like adaptations such as PB2-E627 K and HA-Q222L emerged at low frequencies in principal-infected pigs. It is concluded that pigs are highly susceptible to infection with the mink-derived clade 2.3.4.4b H5N1 HPAIV and provide a favorable environment for HPAIV to acquire mammalian-like adaptations.
Understanding men's body image in the context of their romantic relationships
Creators: name: Goins, Laura Brooke
Publisher: name: No Publisher Supplied
Year: 2010

description: This study examined men's body image in the context of their romantic relationships. One hundred and four heterosexual romantic dyads completed measures assessing men's body satisfaction, perceptions of men's weight change, relationship length, and sexual intimacy. Researchers also collected measures of men's height and weight. Results indicated that men's body satisfaction was negatively associated with both their actual weight status (BMI) and their perception of their weight gain during the relationship; men were more likely to be satisfied with their bodies when they perceived their partners to be and when their partners actually were satisfied with their bodies. Further analyses revealed that men expressed greater body satisfaction when there was a relatively high degree of sexual intimacy in the relationship. Findings are discussed in terms of the contributions to researchers' and practitioners' understanding of men's body satisfaction.