cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: GAINS, JUICE AND BIKINIS: AN ETHNOGRAPHIC EXPLORATION OF WOMEN’S USE OF ANABOLIC-ANDROGENIC STERIODS AND GROWTH HORMONE IN BODYBUILDING
Creators: name: McLean, C
Publisher: name: Liverpool John Moores University
Year: 2020

description: This doctoral thesis explores the lived experience of women who engage in the sport of bodybuilding (BB). In doing so it seeks to determine the role of performance enhancing drugs (PEDs) used to increase muscularity within this hard to reach population. Anabolic androgenic steroids (AAS) and growth hormone (GH) are used to enhance performance and are associated with adverse cardiovascular, hepatic and psychological effects. The use of such illicit market drugs prompts concerns surrounding contamination, the transmission of blood borne viruses and the potential for inaccurate dosage and labelling. The latter is particularly noteworthy for women for whom the dose response curve is markedly steep with respect to androgenic side effects, some of which are irreversible. Traditionally a male domain, women’s BB is currently enjoying an increase in popularity due to the rise of the fitness competitor and the gradual shift towards a lean and muscular ideal in mainstream culture. However, there is a paucity of data pertaining to women’s experiences of PED use within this context and given the potential health concerns associated with them; there is a need for research to underpin suitable public health initiatives for this population. This thesis forms the first steps in informing an appropriate response in the UK. This research draws upon an eighteen-month ethnographic study, which comprised in depth interviews and extensive participant observation, which included a significant auto ethnographic element. By illustrating BB culture, the research situates the decision-making process and justifications surrounding AAS and GH use in women engaging competitively in this sport. It also highlights the rituals and practices embedded in the culture and considers how these influence health and the uptake and engagement with primary and secondary health care settings. Through the application of Bourdieu’s concept of capital, the thesis illustrates that within the context of BB culture and competitive involvement, the decision to AAS and GH is normal and logical. It also exposes the fine line women must tread in order to avoid deviant labelling by both outsiders and members of the community. The research also proposes untapped resources with respect to public health engagement in the form of key cultural members, whose capital resource and field position grant them authority and influence with respect to BB practice.
Quale lingua per l'Europa? / Kiu Lingvo por Eŭropo?
Creators: name: Astori, Davide
Publisher: name: Università degli Studi di Milano
Year: 2012

description: Tradukis Renato Corsetti
description: InKoj. Philosophy & Artificial Languages, Vol 3, No 1 (2012): Which Language for Europe? / Kiu Lingvo por Eŭropo?
Knowledge, dentist confidence and management of periodontal patients among general dentists from Belarus, Lithuania, Macedonia, Moldova and Romania
Creators: name: Aleksejuniene, Jolanta
name: Pūrienė, Alina
name: Rimkervicius, Arunas
name: Amariei, Corneliu
name: Oancea, Roxana
name: Porosencova, Tatiana
name: Porosencov, Egor
name: Nikolovska, Julijana
name: Mirnaya, Elena
name: Serova-Papakul, Aleksandra
name: Eaton, Kenneth A
Publisher: name: BioMed Central
Year: 2020

description: Background: Evidence concerning periodontal practice in Eastern European countries is scarce. The aim of the present study was to investigate periodontal risk knowledge, patient management and self-perceived confidence among General Dentists (GDs) from five Eastern European regarding their provision of periodontal care. Methods: GDs from Belarus, Lithuania, Macedonia, Moldova and Romania participated in a questionnaire survey. Power calculations were used to identify the sample size for each country. The structured questionnaire included several domains of inquiry. The socio-demographic domain inquired about dentist’s age, gender and years of clinical experience. The dental practice domain inquired about practice location, practising or not practising in a group practice and having or not having a periodontist or a dental hygienist in the practice. The distributions of answers across-countries were compared employing one way ANOVA (comparison of means) or Chi square test (comparison of proportions). For each country, the predictors of the study outcomes: a summative knowledge score for periodontal risks and dentist’s confidence level were identified employing either linear or logistic multiple regression models. Results: The sample comprised 390 Belarussian, 488 Lithuanian, 349 Macedonian, 316 Moldovan, and 401 Romanian GDs. The majority of GDs (~ 80%) practiced in urban areas. Age and gender distributions differed significantly among countries. Significant across-country differences were found regarding working/not working in a group practice, having/not having access to a periodontist/dental hygienist and in proportions of patients receiving periodontal treatments or being referred to specialists. None of Macedonian patients nor the majority of Moldovan patients (78%) were referred to periodontists. There were also significant across-country differences in diagnosis, patient management and periodontal knowledge. Only in the Lithuanian cohort were dentists’ confidence levels associated significantly with their knowledge. In all countries, taking a medical history was a consistent and significant predictor of having higher periodontal knowledge score. Except in Belarus, periodontal risk assessment was a significantly consistent predictor of certainty levels associated with the provision of periodontal treatments. Conclusions: There were substantial differences among GDs in the five countries regarding diagnosis, dentist’s confidence and management of periodontal patients.
Contribution à l'analyse du mouvement étudiant de 2012 au Québec. Une analyse interprétative de l'Association pour une solidarité étudiante (ASSÉ)
Creators: name: Régimbald, Karine
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Québec
carrés rouges
ASSÉ
CLASSE
printemps érable
gratuité scolaire
désobéissance civile
démocratie
utopie
Miguel Abensour.

description: Dans cette thèse, nous chercherons à jeter un regard neuf sur le mouvement étudiant de 2012 au Québec. Tout en prenant en compte la dimension critique du mouvement des carrés rouges, nous voulons montrer son inscription dans une logique affirmative, en tant qu’il a été porteur d’'une dimension utopique (au sens où l’entend le philosophe Miguel Abensour). Pour ce faire, nous avons examiné le discours, en particulier, de l'Association pour une solidarité syndicale étudiante (ASSÉ) à partir de trois thématiques qui ont permis de susciter un débat dans l'espace public québécois : la gratuité scolaire, la démocratie directe, la désobéissance civile. De façon transversale, nous avons également analysé la question de la citoyenneté. Notre travail a été motivé par le peu de recherche effectuée sur le sujet au moment d'entamer cette thèse. Sans compter que, sauf quelques exceptions, l'essentiel de la recherche concernant le « printemps québécois » faisait fi de son discours orienté vers l’affirmation. Dans un premier temps nous procéderons à une mise en contexte du « printemps québécois ». Cette première partie, essentiellement descriptive et présentée de façon chronologique, vise à rappeler les événements liés à cette période d'action collective. Dans un second temps, nous nous intéresserons plus particulièrement à l'ASSÉ, le regroupement étudiant qui a mis sur pied la CLASSE. Il sera question de traiter de son contexte d'émergence, de sa culture générationnelle et de ses principes pour ensuite procéder à une analyse interprétative à partir des thématiques identifiées ci-dessus. Au terme de notre travail, apparaîtra une association étudiante qui porte résolument un discours tourné vers l'émancipation, arrimé à une quête de sens, dont le fil conducteur est une idée de l'humanité.
Europa Multilingue? / Multlingva Eŭropo?
Creators: name: Astori, Davide
Publisher: name: Università degli Studi di Milano
Year: 2012

description: Tradukis Renato Corsetti
description: InKoj. Philosophy & Artificial Languages, Vol 3, No 1 (2012): Which Language for Europe? / Kiu Lingvo por Eŭropo?
title: Mehr als eine Substitutionstherapie
title: Mehr als eine Substitutionstherapie
titleType: AlternativeTitle
Creators: name: Jering, Almut
name: Klatt, Anne
name: Günther, Jens
Publisher: name: My University
Year: 2020

description: Keine Frage, die Vision einer in die natürlichen Stoffkreisläufe eingebetteten Wirtschaftsweise ist äußerst attraktiv. Bioökonomische Innovationen sind zweifelsohne notwendig, aber nicht per se gut für Mensch und Umwelt. Nur durch eine deutliche Verringerung unseres Rohstoff- und Energieverbrauchs wird aus einer technikgetriebenen eine nachhaltige Bioökonomie. Quelle: Jering, Almut; Klatt, Anne; Günther, Jens: Mehr als eine Substitutionstherapie / von Almut Jering, Anne Klatt, Jens Günther. In: Bioökonomie : Weltformel oder Brandbeschleuniger? / Oekom e.V. (Hrsg.). Mitherausgegeben vom Umweltbundesamt. - München : Oekom e.V.. - 38 (2020), Seite 17. - ISBN 978-3-96238-230-8
AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils
Creators: name: Bansal, Akanksha
name: Schmidt, Matthias
name: Rennegarbe, Matthies
name: Haupt, Christian
name: Liberta, Falk
name: Stecher, Sabrina
name: Puşcalău-Gîrţu, Ioana
name: Biedermann, Alexander
name: Fändrich, Marcus
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Protein aggregation
subject: DDC 570 / Life sciences
subject: Cryoelectronics
subject: Cryoelectron Microscopy
subject: Protein Aggregates
subject: Elektronenmikroskopie

description: Systemic AA amyloidosis is a world-wide occurring protein misfolding disease of humans and animals. It arises from the formation of amyloid fibrils from serum amyloid A (SAA) protein. Using cryo electron microscopy we here show that amyloid fibrils which were purified from AA amyloidotic mice are structurally different from fibrils formed from recombinant SAA protein in vitro. Ex vivo amyloid fibrils consist of fibril proteins that contain more residues within their ordered parts and possess a higher β-sheet content than in vitro fibril proteins. They are also more resistant to proteolysis than their in vitro formed counterparts. These data suggest that pathogenic amyloid fibrils may originate from proteolytic selection, allowing specific fibril morphologies to proliferate and to cause damage to the surrounding tissue. https://doi.org/10.1038/s41467-021-21129-z OPEN 1
We Only Accept Online Applications: The Effect of HRIS E-Recruitment Technology on Job-Seeker Fairness Perceptions in the Canadian Federal Public Sector
Creators: name: Wesolowski, Peter
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Fairness perceptions
Job-search
Applicant reactions
Organizational Justice
Industrial-Organizational Psychology
Employment Search
E-Recruitment
Human Resources Information Systems
Public Service Commission
Public Administration
Information Systems Success Theory
Procedural Justice
Personnel Selection
Staffing
Government of Canada
Unsupervised Internet Testing
Focus Group

description: Industrial-organizational psychologist Stephen S.W. Gilliland developed a model for studying job-seeker fairness perceptions in 1993 based on existing research in organizational justice. The model includes several rules which will result in job-seeker perceptions of fairness if satisfied and job-seeker perceptions of unfairness if violated. Given the prominence of this model in the literature as well as changes which have occurred in personnel selection (such as human resource information systems, or HRIS, and e-recruitment), scholars have called for a technological re-envisioning of the original model, especially the explanations/descriptions ascribed to each rule. The present study seeks to understand how HRIS e-recruitment technology impacts job-seeker fairness perceptions and in so doing update the Gilliland (1993) model using a qualitative methodology and website success measures from information systems success theory. It contributes to the literature on applicant fairness perceptions by accounting for technological change, and contributes to the field of Public Administration by studying a governmental e-recruitment portal thereby accounting for the particularities of public-sector HRM which is underrepresented in the organizational justice literature. Over the course of one (1) year, twelve (12) job-seekers participated in a series of focus group interviews where they reflected on their experiences applying for jobs in the Canadian federal civil service using the government’s e-recruitment portal. Participants completed profiles, sent applications, communicated with government personnel, and wrote internet tests, among other job-search activities, and reported on their experiences from the perspective of fairness. Results confirm the validity of all original procedural justice rules and offer insight into their application in a recruitment environment where applicants invest considerable time interacting with computerized systems. Two additional rules are also put forth including the ease with which candidates can deceive tests and privacy/trustworthiness using technology. The findings are limited insofar as data gathering took place during a time of reduced hiring activity by the employer and because participation was limited to one (1) specific geographic location.
L’apprendimento e l’insegnamento delle lingue straniere come strumenti per la costruzione di una coscienza democratica / La lernado kaj la instruado de la fremdaj lingvoj kiel iloj por la konstruo de demokrata konscienco
Creators: name: Mezzadri, Marco
Publisher: name: Università degli Studi di Milano
Year: 2012

description: Tradukis Luigi Fraccaroli
description: InKoj. Philosophy & Artificial Languages, Vol 3, No 1 (2012): Which Language for Europe? / Kiu Lingvo por Eŭropo?
Vale la pena sapere il latino? Il latino come presidio dalla menzogna della comunicazione di massa / Ĉu penvaloras scii latinon? Latino kiel garantio kontraŭ la mensogo de la amasa komunikado
Creators: name: Rossi, Giancarlo
Publisher: name: Università degli Studi di Milano
Year: 2012

description: Tradukis Roberto Pigro.

description: InKoj. Philosophy & Artificial Languages, Vol 3, No 1 (2012): Which Language for Europe? / Kiu Lingvo por Eŭropo?
Supplementary document for A matrix-free Levenberg-Marquardt algorithm forefficient ptychographic phase retrieval - 5221763.pdf
Creators: name: Kandel, Saugat
name: Maddali, Siddharth
name: Nashed, Youssef
name: Hruszkewycz, Stephan
name: Jacobsen, Chris
name: Allain, Marc
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental document
Alcoholism treatment digest (Release No. 82, December 15, 1966)
Creators: name: Keller, Mark
Publisher: name: No Publisher Supplied
Year: 1966

description: The Alcoholism Treatment Digest was a subscription-based publication prepared for special clients by the editorial department of the Quarterly Journal of Studies on Alcohol / Journal of Studies on Alcohol from 1950 to 1973 with Mark Keller as editor. It was published in February, April, June, October, and December, summarizing scholarly content on four topics, available to republish with attribution. Some of the reviews were simultaneously published in the "Connecticut Review on Alcoholism" under the identical subtitle "Alcoholism Treatment Digest" every other month. The authors of the reviews were first noted in 1964, in the June issue.Contents, Release No. 821.Treatment of Alcoholic Outpatients with a Long-acting Injection2.A New Technique in Aversion Treatment of Alcoholism3.The Buddy System with Hosp Ital I zed Alcoholics4.Treatment of Alcoholic Families with Nurse Home Visits5.Problem Drinking among American Indians
The Movement for Esperanto: Between Creolization and the Report Grin / La movado por Esperanto: inter kreoliĝo kaj la Raporto Grin
Creators: name: Corsetti, Renato
Publisher: name: Università degli Studi di Milano
Year: 2012

description: Dulingva originalo.
description: InKoj. Philosophy & Artificial Languages, Vol 3, No 1 (2012): Which Language for Europe? / Kiu Lingvo por Eŭropo?
Aboriginal health: not just tuberculosis
Creators: Young, T. Kue
Publisher: name: University of Alberta Library
Year: 1998

"As a disadvantaged group in terms of both their health and socio-economic status, Aboriginal people in North America have long been shown to be at high risk for tuberculosis (TB). It is important to understand and examine this excessive risk of TB among Aboriginal people in the broader context of the overall health trends that the population has undergone since the time of the arrival of Europeans. In the space available, this paper can only provide a very brief overview which highlights a few major themes. Readers who wish to seek further background information about the health of Aboriginal people can consult the monographs listed at the end." (as cited in article)
Fuzzy Cellular Automata in Conjunctive Normal Form
Creators: name: Forrester, David M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: cellular automata
fuzzy cellular automata

description: Cellular automata (CA) are discrete dynamical systems comprised of a lattice of finite-state cells. At each time step, each cell updates its state as a function of the previous state of itself and its neighbours. Fuzzy cellular automata (FCA) are a real-valued extension of Boolean cellular automata which "fuzzifies" Boolean logic in the transition function using real values between zero and one (inclusive). To date, FCA have only been studied in disjunctive normal form (DNF). In this thesis, we study FCA in conjunctive normal form (CNF). We classify FCA in CNF both analytically and empirically. We compare these classes to their DNF counterparts. We prove that certain FCA exhibit chaos in CNF, in contrast to the periodic behaviours of DNF FCA. We also briefly explore five different forms of fuzzy logic, and suggest further study. In support of this research, we introduce novel methods of simulating and visualizing FCA.
Recycling of ghost galaxies: the origin of giant HI ring around NGC 1533
Creators: name: Bekki, Kenji
name: Couch, Warrick
name: Ryan-Weber, Emma
name: Webster, Rachel
Publisher: name: Swinburne
Year: 2024

description: We propose that the giant HI ring recently discovered by HIPASS for S0 galaxy NGC 1533 is formed by unequal-mass merging between gas-rich LSB (low surface brightness: 'ghost'') galaxies and HSB disks. The NGC 1533 progenitor HSB spiral is transformed into a barred S0 during merging and the outer HI gas disk of the LSB is transformed into the giant HI ring. We also discuss two different possibilities for the origin of isolated star-forming regions ('ELdot'' objects) in the giant gas ring.
Constructions discursives de la santé, du corps et de l'obésité de jeunes femmes vivant avec un handicap visuel
Creators: name: Pouliot, Annie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Constructions discursives
Obésité
Santé
Corps
Femmes
Handicap visuel
Santé des populations

description: Cette étude qualitative a pour objectif d’explorer les constructions discursives de la santé, de l’obésité et du corps de jeunes femmes vivant en situation de handicap visuel. Il s’agit, entre autre, d’obtenir des données empiriques afin de développer une meilleure compréhension de la manière dont ces jeunes femmes se sentent interpellées et se positionnent au sein du discours dominant de l’obésité et/ou de discours corporels alternatifs. Des « entre-vues » ont été réalisées auprès de 20 jeunes femmes vivant en situation de handicap visuel, provenant du Québec et de l’Ontario. Les récits des jeunes femmes ont été enregistrés, transcrits et par la suite analysés par le biais d’une analyse du discours guidée par la théorie féministe poststructuraliste. Les résultats sont présentés sous la forme de trois articles. Le premier article porte sur les constructions discursives de la santé des jeunes femmes vivant en situation de handicap visuel, le deuxième article présente les constructions discursives de l’obésité des participantes et finalement, le troisième article expose les manières dont ces jeunes femmes construisent de manière discursive le « corps sain » et s’engagent dans des pratiques de santé normalisantes afin d’atteindre ce « corps sain ». De manière générale, les résultats de l’analyse thématique suggèrent que le handicap de nature visuel n’empêche pas les jeunes femmes de « visualiser » les images corporelles et les « corps gros » ainsi que de construire la santé en termes strictement corporels et comme étant de responsabilité individuelle via l’adoption de pratiques disciplinaires. L’analyse poststructuraliste a permis d’observer les positions multiples et fluides que les jeunes femmes adoptent en tant que « sujets » : à certains moments en tant que sujets néolibéraux, reproduisant sans questionner les éléments de différents discours patriarcaux dominants (i.e., obésité, responsabilité personnelle et morale envers la santé, féminité et capacitisme) mais à d’autres moments en tant que sujets « poststructuralistes » capables d’apporter un regard critique sur les discours dominants et ainsi de reconstruire la notion de santé, d’obésité et de corps sain autrement et de manière moins oppressive.
Pestizide im Wasser: Da schwimmt was mit
Creators: name: Hilliges, Falk
name: Hitzfeld, Kristina
name: Koschorreck, Jan
name: Müller, Alexandra
Publisher: name: My University
Year: 2022
Subjects: Landwirtschaft

description: Umweltfachleute weisen regelmäßig nach, wie stark Flüsse, Seen, Küstengewässer und Grundwasser durch Pestizide belastet sind. Die Schadstoffe stammen häufig aus der Landwirtschaft und gelangen durch Versickerung, Oberflächenabfluss und Abdrift in die Gewässer. Quelle: https://www.boell.de/
Are perceived barriers to accessing health care associated with inadequate antenatal care visits among women of reproductive age in Rwanda?
Creators: name: Nisingizwe, Marie P.
name: Tuyisenge, Germaine
name: Hategeka, Celestin
name: Karim, Mohammad Ehsanul
Publisher: name: BioMed Central
Year: 2020

description: Background: Maternal and child mortality remain a global health concern despite different interventions that have been implemented to address this issue. Adequate antenatal care (ANC) is crucial in reducing maternal and neonatal morbidity and mortality. However, in Rwanda, there is still suboptimal utilization of ANC services. This study aims to assess the relationship between perceived barriers to accessing health care and inadequate ANC visits among women of reproductive age in Rwanda. Methods: This study is cross-sectional using secondary data from the 2014–15 Rwanda demographic and health survey (RDHS). The study included 5876 women aged 15–49 years, and the primary outcome of the investigation was inadequate ANC visits defined as delayed first ANC visit and non-completion of at least four recommended visits during the pregnancy period. The primary exposure was perceived barriers to accessing health care, operationalized using the following 4 variables: distance to the health facility, getting money for treatment, not wanting to go alone and getting permission to go for treatment. A survey-weighted multivariable logistic regression analysis and backward elimination method based on Akaike information criterion (AIC) was used to select the final model. We conducted a number of sensitivity analyses using stratified and weighting propensity score methods and investigated the relationship between the outcome and each barrier to care separately. Results: Of 5, 876 women included in the analysis, 53% (3132) aged 20 to 34 years, and 44% (2640) were in the lowest wealth index. Overall, 64% (2375) of women who perceived to have barriers to health care had inadequate ANC visits. In multivariable analysis, women who perceived to have barriers to health care had higher odds of having inadequate ANC visits (OR: 1.14; 95% CI: 0.99, 1.31). However, the association was borderline statistically significant. The findings from sensitivity analyses were consistent with the main analysis results. Conclusion: The study suggests a positive association between perceived barriers to health care access and inadequate ANC visits. The findings speak to a need for interventions that focus on improving access to health care in Rwanda to increase uptake of ANC services.
Supplementary document for A matrix-free Levenberg-Marquardt algorithm forefficient ptychographic phase retrieval - 5221763.pdf
Creators: name: Kandel, Saugat
name: Maddali, Siddharth
name: Nashed, Youssef
name: Hruszkewycz, Stephan
name: Jacobsen, Chris
name: Allain, Marc
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplemental document
Pathogenesis of rheumatoid arthritis: Insights into mechanisms of synovial hyperplasia and of reactive nitrogen species mediated inflammatory damage.
Creators: name: Brun, Jan.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Health Sciences, Pathology.

description: Synovial hyperplasia is a hallmark of rheumatoid arthritis (RA). This pathological change may be due to an increase in cell proliferation and/or a decrease in cell death (apoptosis). However, the rates at which these opposing mechanisms occur in the arthritic and control synovium, remain a subject of debate. Our objective was to address this debate using recently developed polyclonal antibodies to thymidylate synthase (TS, another potential cell proliferation marker), and activated caspase 3 and cleaved polyADPribose polymerase (PARP p85), two markers of apoptosis. PCNA and Ki-67, two well characterized proliferation markers were also used in this study. Germinal centers of human tonsil tissue were used as positive controls for proliferation and apoptosis. Another equally important factor in RA is the role of reactive nitrogen and oxygen species (RNOS) such as nitric oxide (NO) and superoxide (O 2-) in inflammation mediated protein damage. Such damage is evidenced by the immunohistochemical detection of nitrotyrosine in a variety of animal models and human inflammatory disorders. Therefore, I studied arthritic joint tissue for the presence of protein nitrotyrosine using immunohistochemical and immunoblotting techniques. (Abstract shortened by UMI.)
Assessing and improving the enablers of innovation: the development of an innovation capability assessment instrument
Creators: name: Ottaviano, Michael E.
Publisher: name: Swinburne
Year: 2024

description: The ability to successfully innovate on a sustained basis is critical in today's 'hyper-competitive' environment characterised by increasingly rapid technological change and shortening product life cycles, and where competitors quickly imitate sources of competitive advantage. At the same time, organisations find managing innovation difficult; both larger firms who fight to avoid being outplayed by smaller, more nimble competitors, and smaller firms struggling to compete against the resources and reach of larger, global competitors. This research develops an assessment instrument designed to assist organisations to improve their ability to innovate. An inductive, case-based methodology is adopted utilising action research techniques to develop the Innovation Capability Assessment instrument. The starting point of the research was an extensive analysis of the corporate entrepreneurship and innovation literature. The literature provided a basis for understanding what question areas might need to be included in such an instrument and led to the development of an initial theoretical framework and a preliminary assessment instrument. The preliminary assessment instrument was further developed and refined via five exploratory case studies. Three subsequent confirmatory case studies were used to validate the instrument's effectiveness. The case studies were carried out at Australian organisations operating within a variety of industries and of varying sizes, all of whom were looking to improve their innovation performance. Data was collected through interviews with key members of each organisation and through assessment and action planning workshops involving participants from a cross-section of each organisation. The case studies led to additional assessment questions being added to the instrument, and the rationalisation of others. This research identifies the enablers of organisational innovation and finds that these are common to all the case organisations involved in the fieldwork. The innovation enablers form the basis of the Innovation Capability Assessment instrument that measures innovation performance against 21 questions within three key assessment areas: strategic management of innovation, the internal environment, and a series of innovation competencies. The relative importance of each innovation enabler to the organisation is also assessed. The Innovation Capability Assessment instrument is shown to be very relevant across a variety of organisation types and sizes. In addition, it is useful for an organisation to identify and prioritise weaknesses, and develop actions for improving their innovation capability.
MPEC 2024-Q30 : 2024 PS7
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 PS7

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Evaluating Angiotensin II Type 1 Receptor Changes in Post- Renal Insufficiency and in Left Anterior Descending Artery Ligation Animal Models Using [11C]Methyl-Candesartan
Creators: name: Mackasey, Kumiko
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Angiotensin II Type 1 Receptor
11C]Methyl-Candesartan
Therapy in cardiovascular patients
ATIR
Left Anterior Descending Artery Ligation /Reperfusion

description: Non invasive in vivo imaging will lead to better understanding of Angiotensin II Type 1 Receptor’s (AT1R) role in disease progression and may guide therapy in cardiovascular patients. Two models were used in this project: 5/6 nephrectomy and transient left anterior descending (LAD) ligation. Rats were scanned with [13N]ammonia and [11C]methyl-candesartan, both of which are Positron Emission Tomography (PET) tracers, at 8 weeks (nephrectomy) and 2 weeks (LAD ligation) after surgery. Western blot analysis was used to corroborate PET data. Nephrectomy: Renal AT1R image analysis displayed a 40% decrease in kidney AT1R in nephrectomized animals compared to sham (p<0.05) which was confirmed with Western blot and biodistribution. LAD ligation: Left Ventricle AT1R Western blot analysis exhibited a 60% increase in 20min ligation (p<0.05) with maintained myocardial blood flow. In conclusion, changes in renal AT1R were successfully imaged using [11C]methyl-candesartan in nephrectomized animals, and 20min LAD ligation/reperfusion is an appropriate model to image an increase in cardiac AT1R following ischemic injury.
Lessons learnt on recruitment and fieldwork from a pilot European human biomonitoring survey
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: Human-Biomonitoring

description: Within the European Environment and Health Action Plan an initiative to establish a coherent human biomonitoring approach in Europe was started. The project COPHES (COnsortium to Perform Human biomonitoring on a European Scale ) developed recommendations for a harmonized conduct of a human biomonitoring (HBM) survey which came into action as the pilot study DEMOCOPHES (DEMOnstration of a study to COordinate and Perform Human biomonitoring on a European Scale). Seventeen European countries conducted a survey with harmonized instruments for, inter alia, recruitment, fieldwork and sampling, in autumn/winter 2011/2012. Based on the countries' experiences of conducting the pilot study, following lessons learnt were compiled: the harmonized fieldwork instruments (basic questionnaire, urine and hair sampling) turned out to be very valuable for future HBM surveys on the European scale. A school approach was favoured by most of the countries to recruit school-aged children according to the established guidelines and country specific experiences. To avoid a low participation rate, intensive communication with the involved institutions and possible participants proved to be necessary. The communication material should also include information on exclusion criteria and offered incentives. Telephone contact to the participants the day before fieldwork during the survey can prevent the forgetting of appointments and first morning urine samples. To achieve comparable results on the European scale, training of interviewers in all issues of recruitment, fieldwork and sampling through information material and training sessions is crucial. A survey involving many European countries needs time for preparation and conduct. Materials for quality control prepared for all steps of recruitment, fieldwork and sampling proved to be important to warrant reliable results.Quelle: http://www.sciencedirect.com
Acute Cannabinoid Treatment 'in vivo' Causes an Astroglial CB1R-Dependent LTD At Excitatory CA3-CA1 Synapses Involving NMDARs and Protein Synthesis
Creators: name: Kesner, Philip
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Cannabinoid
NMDAR
Protein Synthesis
CB1R
Hippocampus
Philip Kesner
Astrocyte
Knockout mice
fEPSP
Working Memory
LTD
Long-term depression
in vivo
Synaptic Plasticity

description: Cannabinoids have been shown to alter synaptic plasticity but the mechanism by which this occurs at hippocampal CA3-CA1 synapses in vivo is not yet known. Utilizing in vivo electrophysiological recordings of field excitatory postsynaptic potentials (fEPSP) on anesthetized rats and mice as well as three lines of conditional knockout mouse models, the objective was to show a two-part mechanistic breakdown of cannabinoid-evoked CA3-CA1 long-term depression (LTD) in its induction as well as early and later-phase expression stages. It was determined that this cannabinoid-induced in vivo LTD requires cannabinoid type-1 receptors (CB1Rs) on astrocytes, but not CB1Rs on glutamatergic or GABAergic neuronal axons/terminals. Pharmacological testing determined that cannabinoid-induced in vivo LTD also requires activation of NMDA receptors (NMDAR) and subsequent postsynaptic endocytosis of AMPA receptors (AMPAR). There exists a clear role for NR2B-containing NMDARs in a persistent, transitory form, potentially related to prolonged or delayed glutamate release (possibly as a result of the astrocytic network). A key determination of the expression phase is the involvement of new protein synthesis (using translation and transcription inhibitors) – further evidence of the long-term action of the synaptic plasticity from a single cannabinoid dose.
Can guided introspection help avoid rationalization of meat consumption? Mixed-methods results of a pilot experimental study
Creators: name: Frank, Pascal
name: Heimann, Katrin
name: Kolbe, Viktoria
Publisher: name: My University
Year: 2022
Subjects: Rationalisierung
Nachhaltiger Konsum

description: The need for reducing meat consumption in affluent countries is increasingly recognized as crucial to minimizing carbon footprint. However, confronting individuals with rational arguments can prompt emotional discomfort, which is often relieved by engaging in rationalization processes stabilizing current consumption patterns. Mindfulness research suggests that making people aware of their emotional reactions through introspection can reduce these rationalization processes. In this mixed-method pilot experimental study, we inquired whether a single guided introspection, inspired by the micro-phenomenological interview technique, can alter individuals' experience of and abilities to deal with cognitive dissonance. Furthermore, we asked if such an intervention can stimulate attitude or intention changes concerning meat consumption. After inducing cognitive dissonance by exposing participants to pictures of the slaughter of a cow, the intervention group (n = 36) participated in the guided introspection, while the control group (n = 39) played solitaire. Self-report questionnaire measures of emotional discomfort, rationalization strategies, and attitudes towards meat consumption were administered before and after the intervention. Also, open-ended responses to participants' experience of the study were analyzed. Quantitative results show significantly lower negative attitudes toward reducing meat consumption in the intervention group compared to the control group (partial 2 = 0.107). Qualitative results indicate that these participants are more aware of negative emotions while engaging less in rationalization strategies. We conclude that our study indicates some potential for guided introspection to affect dissonance resolution and provide suggestions for future research. © 2022 The Authors.
Evaluation of Wall Pressure Spectrum Models for Fan Noise Prediction
Creators: name: Sanjosé, Marlène
Publisher: name: Acoustics Week in Canada, Montréal, 2023
Year: 2023

description: Talk given in the aeroacoustic session of the Acoustics Week in Canada which was held in Montréal (QC, Canada) in October 2023.

Presentation without paper (abstract only).
title: Predicting recurrent chat contact in a psychological intervention for the youth using natural language processing
Creators: name: Hornstein, Silvan
name: Scharfenberger, Jonas
name: Lueken, Ulrike
name: Wundrack, Richard
name: Hilbert, Kevin
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: Health care
subject: Public health
subject: 150 Psychologie

description: The article processing charge was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – 491192747 and the Open Access Publication Fund of Humboldt-Universität zu Berlin.
description: Chat-based counseling hotlines emerged as a promising low-threshold intervention for youth mental health. However, despite the resulting availability of large text corpora, little work has investigated Natural Language Processing (NLP) applications within this setting. Therefore, this preregistered approach (OSF: XA4PN) utilizes a sample of approximately 19,000 children and young adults that received a chat consultation from a 24/7 crisis service in Germany. Around 800,000 messages were used to predict whether chatters would contact the service again, as this would allow the provision of or redirection to additional treatment. We trained an XGBoost Classifier on the words of the anonymized conversations, using repeated cross-validation and bayesian optimization for hyperparameter search. The best model was able to achieve an AUROC score of 0.68 (p < 0.01) on the previously unseen 3942 newest consultations. A shapely-based explainability approach revealed that words indicating younger age or female gender and terms related to self-harm and suicidal thoughts were associated with a higher chance of recontacting. We conclude that NLP-based predictions of recurrent contact are a promising path toward personalized care at chat hotlines.
L'administration des biens temporels de la paroisse d'après le code de droit canonique de 1983 : application à l'église du Cameroun.
Creators: name: Signié, Jean-Marie.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Religion, General.

description: La présente étude sur les législations et canons en matière de divorce rédigés ou commentés par Bar Hebraeus se propose de montrer combien il est difficile et délicat de les appliquer à des décisions concrètes. Le mariage est une institution naturelle, fondée sur la dualité sexuelle de l'espèce humaine l'homme et la femme sont attirés l'un vers l'autre et invités à s'unir et former une communauté, pour toute la vie. Par nature, le mariage présente les propriétés essentielles d'unité et d'indissolubilité. En tenant compte de l'expérience humaine et des réalités sociales, l'Église syriaque orthodoxe d'Antioche a légiféré sur les motifs légitimes de séparation et de divorce. Pour elle, le divorce proprement dit, ou divorce pénal, ne peut être envisagé que comme une mesure exceptionnelle, une solution extrême à de graves problèmes d'infidélité conjugale. Elle propose ainsi la dissolution du lien matrimonial, ou divorce remède, tout en reconnaissant le rôle de l'économie dans les décisions finales relatives aux cas particuliers. Selon son enseignement et celui de Bar Hebraeus, le mariage conclu et consommé ne peut être dissous que pour les motifs déterminés par la loi et le divorce est considéré comme un mal inévitable et une affaire très sérieuse. Je crois, et j'affirme, qu'aucune autorité humaine ne peut dissoudre le lien matrimonial et que, si un tribunal ecclésiastique peut accorder un divorce, lorsque l'exigent les intérêts supérieurs des fidèles, c'est seulement par un don gracieux de Dieu lui-même. Le droit reconnaît la nécessité du divorce et de la séparation pour protéger l'institution familiale des atteintes du péché. Il incombe aux pasteurs de prendre le relais du droit dans le domaine spirituel et de recourir à des moyens de correction pacifique pour tenter de contribuer à reconstruire la relation conjugale. J'espère avoir démontré que l'enseignement de l'Église syriaque orthodoxe d'Antioche en matière de divorce repose sur des fondements bibliques et patristiques et que sa pratique s'inspire de motifs constitutifs déterminés par sa législation ecclésiastique. Pour elle, le divorce constitue soit une solution pénale, soit une solution thérapeutique et seul un tribunal eccléastique a compétence pour établir la réalité des motifs invoqués.
Y-box binding protein-1 is crucial in acquired drug resistance development in metastatic clear-cell renal cell carcinoma
Creators: name: D’Costa, Ninadh M
name: Lowerison, Matthew R
name: Raven, Peter A
name: Tan, Zheng
name: Roberts, Morgan E
name: Shrestha, Raunak
name: Urban, Matthew W
name: Monjaras-Avila, Cesar U
name: Oo, Htoo Z
name: Hurtado-Coll, Antonio
name: Chavez-Munoz, Claudia
name: So, Alan I
Publisher: name: BioMed Central
Year: 2020

description: Background: Renal cell carcinoma (RCC) is a highly vascular tumor and patients with low risk metastatic RCC of clear-cell histological sub-type (mccRCC) are treated with tyrosine-kinase inhibitors (TKIs), sunitinib, as the first-line of treatment. Unfortunately, TKI resistance eventually develops, and the underlying molecular mechanism is not well understood. Methods: RCC cell-line with metastatic clear-cell histology (Caki-1), and patient samples were analysed to identify the role of Y-box binding protein 1 (YB-1) and ATP-binding cassette sub-family B member 1 (ABCB-1) in acquired sunitinib-resistance development. Caki-1 was conditioned with increasing sunitinib doses to recapitulate acquired resistance development in clinics. Sunitinib-conditioned and wild-type Caki-1 were subjected to cell viability assay, scratch assay, chicken embryo chorioallantoic membrane engraftment and proteomics analysis. Classical biochemical assays like flow cytometry, immunofluorescent staining, immunohistochemical staining, optical coherence tomography imaging, Western Blot and RT-PCR assays were applied to determine the possible mechanism of sunitinib-resistance development and the effect of drug treatments. Publicly available data was also used to determine the role of YB-1 upregulation in ccRCC and the patients’ overall survival. Results: We demonstrate that YB-1 and ABCB-1 are upregulated in sunitinib-resistant in vitro, ex vivo, in vivo and patient samples compared to the sensitive samples. This provides evidence to a mechanism of acquired sunitinib-resistance development in mccRCC. Furthermore, our results establish that inhibiting ABCB-1 with elacridar, in addition to sunitinib, has a positive impact on reverting sunitinib-resistance development in in vitro, ex vivo and in vivo models. Conclusion: This work proposes a targeted therapy (elacridar and sunitinib) to re-sensitize sunitinib-resistant mccRCC and, possibly, slow disease progression.
Building an organisational learning architecture for strategic renewal: an autoethnography of action learning
Creators: name: Liu, Lucy
Publisher: name: Swinburne
Year: 2024

description: This thesis analyses how the concept of action learning can be employed to build an organisational learning framework in pursuit of strategic renewal in a complex manufacturing environment. The thesis presents an analytic autoethnographic account of how action learning was used to create an organisational learning framework in the pursuit of strategic renewal at the Toyota Motor Corporation of Australia (TMCA), Melbourne, during the period 2000-2008. The scope of the thesis is restricted to this one company in order to benefit from a detailed analysis of a case study in a large and complex manufacturing environment suddenly faced with the need for an immediate strategic renewal within the company. Analytic autoethnography (Atkinson, 2006) has been chosen as the methodology of choice to take advantage of the researcher's insider status at TMCA. As a complete member- researcher within the social world under study the researcher has enjoyed the most compelling kind of 'being there' for the ethnographer. The fine-grained nature of the data gathered and the informed interpretation of the researcher could probably not have been achieved through the use of any alternative methodology. The analytic autoethnographic analysis is framed around the 4i model of intuition, interpretation, integration, and institutionalisation (Crossan, Lane, and White, 1999). These authors initially presented an embryonic model in the literature and invited other researchers to further develop the framework. This challenge has been taken up in the thesis. The thesis presents a more nuanced analysis of the 4i model by developing an organisational learning architecture across multiple organisational levels (individual, group, and organisation) through the use of action learning in pursuit of strategic renewal at TMCA. A significant contribution is made to the extant theoretical literature through the development of an integrated model combining the 4i model, action learning, and experiential learning. The thesis also analyses some specific implications of the findings for lean manufacturing in general, and Toyota systems in particular, by suggesting how action learning principles can be absorbed into the newly evolving framework of Toyota Global Management Systems and Practices and its four components of Toyota Way, Toyota Business Practices (TBP), on-the job training (OJT), and Hoshin Kanri (business plan for long-term prosperity).