cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The First Day in the Life of a Magnetar: Evolution of the Inclination Angle, Magnetic Dipole Moment and Braking Index of Millisecond Magnetars During Gamma-Ray Burst Afterglows
Creators: name: Mus, Sinem Sasmaz
name: Çıkıntoğlu, Sercan
name: Aygun, Ugur
name: Andaç, I. Ceyhun
name: Ekşi, K. Yavuz
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The afterglow emission of some gamma-ray bursts (GRBs) show a shallow decay (plateau) phase implying continuous injection of energy. The source of this energy is very commonly attributed to the spin-down power of a nascent millisecond magnetar. The magnetic dipole radiation torque is considered to be the mechanism causing the spin-down of the neutron star. This torque has a component working for the alignment of the angle between rotation and magnetic axis, i.e., inclination angle, which has been neglected in modelling GRB afterglow light curves. Here, we demonstrate the evolution of the inclination angle and magnetic dipole moment of nascent magnetars associated with GRBs. We constrain the initial inclination angle, magnetic dipole moment and rotation period of seven magnetars by modelling the seven long-GRB afterglow light curves. We find that, in its first day, the inclination angle of a magnetar decreases rapidly. The rapid alignment of the magnetic and rotation axis may address the lack of persistent radio emission from mature magnetars. We also find that in three cases the magnetic dipole moments of magnetars decrease exponentially to a value a few times smaller than the initial value. The braking index of nascent magnetars, as a result of the alignment and magnetic dipole moment decline, is variable during the afterglow phase and always greater than three.
description: 13 pages, 8 figures, 4 tables, accepted for publication in ApJ
title: Developing Olfactory Ensheathing Cells for ex vivo Delivery of GDNF
Creators: name: Cameron, Nicholas John
Publisher: name: Griffith University
Year: 2010
Subjects: subject: Olfactory ensheathing cells
subject: Central nervous system
subject: Immunopanning
subject: GDNF
subject: EGPF

description: Olfactory ensheathing cells have well described neurotrophic properties and can promote repair of damaged nerves in the central nervous system. Genetically engineering these cells to deliver therapeutic proteins could 'supercharge' their existing abilities to repair damaged nerves and prevent neurodegeneration in disease. The present study used retroviral vectors to engineer human olfactory ensheathing cells to co-express the potent neurotrophin GDNF and reporter genes under a tetracycline-inducible promoter. The goal here was to provide proof of concept for using olfactory ensheathing cells (OECs) for controlled ex vivo delivery of GDNF in preclinical studies. Until now, OECs from the olfactory mucosa have not been examined or developed for this purpose. Here a systematic evaluation of OECs revealed their suitability for developing ex vivo gene therapies.
Baryogenesis from axion inflation
Creators: name: Domcke, Valerie
name: von Harling, Benedict
name: Morgante, Enrico
name: Mukaida, Kyohei
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The coupling of an axion-like particle driving inflation to the Standard Model particle content through a Chern-Simons term generically sources a dual production of massless helical gauge fields and chiral fermions. We demonstrate that the interplay of these two components results in a highly predictive baryogenesis model, which requires no further ingredients beyond the Standard Model. If the helicity stored in the hyper magnetic field and the effective chemical potential induced by the chiral fermion production are large enough to avoid magnetic diffusion from the thermal plasma but small enough to sufficiently delay the chiral plasma instability, then the non-vanishing helicity survives until the electroweak phase transition and sources a net baryon asymmetry which is in excellent agreement with the observed value. If any of these two conditions is violated, the final baryon asymmetry vanishes. The observed baryon asymmetry can be reproduced if the energy scale of inflation is around $H_\text{inf} \sim 10^{10}$ - $10^{12}$ GeV with a moderate dependence on inflation model parameters.
description: 19 pages, 6 figures; v2: published version
Oxypoda (Deropoda) andalusica ASSING 2003
Creators: name: Assing, V.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Oxypoda
Oxypoda andalusica

description: Oxypoda (Deropoda) andalusica ASSING 2003
M a t e r i a l e x a m i n e d: Spain: 4 exs., Andalucía, Sierra de los Filabres, S Serón, 37°16'N, 02°31'W, 1800 m, stony pasture with trees and bushes, under stones, 19.III.2008, leg. Assing (cAss).
C o m m e n t: This recently described species was previously known only from few localities in the Sierra de Segura and the Sierra de las Nieves, Andalucía (ASSING 2003b).
description: Published as part of Assing, V., 2008, Nine new species and additional records of Staphylinidae from southern Spain, with new synonymies (Insecta: Coleoptera), pp. 1301-1325 in Linzer biologische Beiträge 40 (2) on page 1311, DOI: 10.5281/zenodo.5430659
Student-t Processes for Degradation Analysis
Creators: name: Chien-Yu Peng
name: Ya-Shan Cheng
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: Stochastic processes are widely used to analyze degradation data, and the Gaussian process is a particularly common one. In this article, we propose a robust statistical model using a Student-t process to assess the lifetime information of highly reliable products. This model is statistically plausible and demonstrates a substantially improved fit when applied to real data. A computationally accurate approach is proposed to calculate the first-passage-time density function of the Student-t degradation-based process; related properties are investigated as well. In addition, this article provides parameter estimation using the EM-type algorithm and a simple model-checking procedure to evaluate the appropriateness of the model assumptions. Several case studies are performed to demonstrate the flexibility and applicability of the proposed model with random effects and explanatory variables. Technical details, datasets and R codes are available as supplementary materials.
title: The Australian Housing Market: Price Dynamics and Capital Stock Growth
Creators: name: Mikhailitchenko, Serguei
Publisher: name: Griffith University
Year: 2008
Subjects: subject: Australian housing market
subject: price dynamics
subject: capital stock growth
subject: housing market
subject: Australia
subject: error-correction mechanism
subject: ECM

description: This study was motivated by the desire to contribute to the understanding of the movement of house prices and the role of the so-called economic ‘fundamentals’ in the housing market, especially within an Australian context. The core objective of this thesis is to aid understanding of the economic and other mechanisms by which the Australian housing market operates. We do this by constructing an analytical framework, or model, that encompasses the most important characteristics of the housing market. This thesis examines two important aspects of the Australian housing market: movements of house prices and changes in the net capital stock of dwellings in Australia. Movements of house prices are modelled from two perspectives: firstly, using the ‘fundamental’ approach, which explains the phenomena by changes in such ‘fundamental’ explanatory variables as income, interest rates, population and prices of building materials, and secondly, by analysing spatial interdependence of house prices in Australian capital cities. Changes in stock of dwellings were also modelled on the basis of a ‘fundamental’ approach by states and for Australia as a whole.
Rheology investigation of propane gas hydrate crystallization in water/asphaltene-resin-wax deposit emulsions
Creators: name: Huang, Bin
name: Li, Jiaoyang
name: Fu, Cheng
name: Guo, Tianyue
name: Ding, Chang
name: Zhang, Lu
name: Guo, Wei
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Mental Health

description: Hydrates and asphaltene-resin-wax deposits are increasingly concerned as a terrible problem in the field of offshore oil and gas production and transportation. The rheological property of propane gas hydrate in the water-in-asphaltene-resin-wax deposit (W/ARWD) emulsion was in situ characterized by experiments in a stress-controlled rheometer with particular focus on the effects of pressure, emulsion component ratio, and deposit composition. Results demonstrated that the higher pressure could accelerate hydrate formation and aggregation in a shorter time, and exhibit more obvious shear-thinning behavior of hydrate slurry. The emulsion component ratio was positive correlation with the hydrate slurry viscosity and the yield stress, was negative correlation with the hydrate crystallization time. Asphaltene and wax occupied more nucleation sites on water droplets and formed physical barriers to hinder the hydrate crystallization. The promoting effect of resin on hydrate crystallization was stronger than inhibiting effect. With the increase of asphaltene, resin, and wax contents, the yield stress of hydrate slurry gradually increased, and the effect of wax on the yield stress was stronger than asphaltene and resin, which was associated with the multiple effects of capillary bridge between hydrate particles and spatial network of wax crystals. Furthermore, the coupling effect of pressure, emulsion component ratio, and deposit composition on the rheological properties of hydrate slurry had been studied. This study is significant in that it can helpfully support the development of subsea multiphase flow assurance in petroleum production.
Wave breaking for shallow water models with time decaying solutions
Creators: name: Freire, Igor Leite
Publisher: name: arXiv
Year: 2019
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 35A01, 35L65, 37K05

description: A family of Camassa-Holm type equations with a linear term and cubic and quartic nonlinearities is considered. Local well-posedness results are established via Kato's approach. Conserved quantities for the equation are determined and from them we prove that the energy functional of the solutions is a time-dependent, monotonically decreasing function of time, and bounded from above by the Sobolev norm of the initial data under some conditions. The existence of wave breaking phenomenon is investigated and necessary conditions for its existence are obtained. In our framework the wave breaking is guaranteed, among other conditions, when the coefficient of the linear term is sufficiently small, which allows us to interpret the equation as a linear perturbation of some recent Camassa-Holm type equations considered in the literature.
description: This work corresponds to the accepted version in the Journal of Differential Equations and does not have minor changes made during the proofs
Odontoscelis (Obscuromorpha) hispidula JAKOVLEV 1874
Creators: name: Dursun, A.
name: Fent, M.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Scutelleridae
Odontoscelis
Odontoscelis hispidula

description: Odontoscelis (Obscuromorpha) hispidula JAKOVLEV 1874
M a t e r i a l: loc. 33, 1.
F u t t e r p f l a n z e n: Verschiedene Bodenpflanzen.
V e r b r e i t u n g i n d e r T ü r k e i: Konya (SEIDENSTÜCKER 1960).
description: Published as part of Dursun, A. & Fent, M., 2010, Systematische und faunistische Untersuchungen über die Überfamilie Pentatomoidea (Insecta, Heteroptera) aus dem Kelkit-Tal der Türkei, pp. 587-598 in Linzer biologische Beiträge 42 (1) on page 590, DOI: 10.5281/zenodo.5332773
Spatiotemporal Flow L-function: a new method for identifying spatiotemporal clusters in geographical flow data
Creators: name: Yan, Xiaorui
name: Pei, Tao
name: Shu, Hua
name: Song, Ci
name: Wu, Mingbo
name: Fang, Zidong
name: Chen, Jie
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: A geographical flow (hereafter flow) is defined as a movement between locations at two different times. A group of spatiotemporal flows can be viewed as a cluster if their origins and destinations are both spatiotemporally concentrated. Identifying spatiotemporal flow clusters may help reveal underlying spatiotemporal mobility trends or intensive relationships between regions. Despite recent advances in flow clustering methods, most only consider spatial attributes and ignore temporal information, and may fail to differentiate space-close but time-separated clusters. To this end, we derive global and local versions of the Spatiotemporal Flow L-function, extended from the classical L-function for points, and thereby construct a clustering method. First, the global version is utilized to check whether flow data contain clusters and estimate the spatial and temporal scales of the clusters. The local version is then employed to extract the clusters with the estimated scales. Experiments of simulated data demonstrate that our method outperforms three state-of-the-art methods in identifying spatiotemporal flow clusters with arbitrary shapes and different densities and reducing subjectivity in the parameter selection process. A case study with taxi data shows that our method reveals residents’ spatiotemporal moving patterns, including rush-hour commuting and whole-daytime transferring among railway stations.
Exploring the evidence for a large local void with supernovae Ia data
Creators: name: Luković, Vladimir V.
name: Haridasu, Balakrishna S.
name: Vittorio, Nicola
Publisher: name: arXiv
Year: 2019
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In this work we utilise the most recent publicly available type Ia supernova (SN Ia) compilations and implement a well formulated cosmological model based on Lemaître-Tolman-Bondi metric in presence of cosmological constant $Λ$ ($Λ$LTB) to test for signatures of large local inhomogeneities at $z\leq0.15$. Local underdensities in this redshift range have been previously found based on luminosity density (LD) data and galaxy number counts. Our main constraints on the possible local void using the Pantheon SN Ia dataset are: redshift size of $z_{\rm size}=0.068^{+0.021}_{-0.030}$; density contrast of $δΩ_0/Ω_0=-10.5_{-7.4}^{+9.3}\%$ between 16th and 84th percentiles. Investigating the possibility to alleviate the $\sim9\%$ disagreement between measurements of present expansion rate $H_0$ coming from calibrated local SN Ia and high-$z$ cosmic microwave background data, we find large local void to be a very unlikely explanation alone, consistently with previous studies. However, the level of matter inhomogeneity at a scale of $\sim$100Mpc that is allowed by SN Ia data, although not expected from cosmic variance calculations in standard model of cosmology, could be the origin of additonal systematic error in distance ladder measurements based on SN Ia. Fitting low-redshift Pantheon data with a cut $0.023
description: Equivalent to version published in MNRAS, 12 pages, 7 figures, 1 table. Comments and questions are welcome
Additional file 1 of Fetal weight estimation based on deep neural network: a retrospective observational study
Creators: name: Wang, Yifei
name: Shi, Yi
name: Zhang, Chenjie
name: Su, Kaizhen
name: Hu, Yixiao
name: Chen, Lei
name: Wu, Yanting
name: Huang, Hefeng
Publisher: name: figshare
Year: 2023
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Science Policy

description: Additional file 1: Table S1. Basic characteristics of the cohort data. Table S2. The RMSE (g) of different layers and nodes during pre-training. Table S3. The mean and 95% confidence interval of percentage error (PE), absolute percentage error (APE), absolute error (AE) , root-mean-square error (RMSE), and predicting accuracy of all methods. Table S4. Ten predictive features selected for the non-first delivery group and the entire cohort. Table S5. The mean and 95% confidence interval of percentage error (PE), absolute percentage error (APE), absolute error (AE) , root-mean-square error (RMSE), and predicting accuracy of DNN models of firstdelivery group, non-first delivery group and the entire cohort. Table S6. The mean and 95% confidence interval of percentage error (PE), absolute percentage error (APE), absolute error (AE) , root-mean-square error (RMSE), and predicting accuracy DNN models after feature selection. Table S7. The cut-off point, sensitivity when the specificity at 90% of all methods on macrosomia prediction. The AUC and its 95% confidence interval of all methods. Table S8. The mean and 95% confidence interval of percentage error (PE), absolute percentage error (APE), absolute error (AE) , root-mean-square error (RMSE), and predicting accuracy of DNN and MLR models with only 4 ultrasound features compare to Hedlock. Figure S1. The performance of DNN and MLR models with only 4 ultrasound features compare to Hedlock. The mean deviation (± 1 SD), mean absolute error (MAE), B) mean absolute percentage error (MAPE), C) and root-mean-square error (RMSE), D) and their 95% confidence interval of EFW in different methods.
Sources of error and variability in particulate matter sensor network measurements
Creators: name: Zuidema, Christopher
name: Stebounova, Larissa V.
name: Sousan, Sinan
name: Geb Thomas
name: Koehler, Kirsten
name: Peters, Thomas M.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer

description: The quality of mass concentration estimates from increasingly popular networks of low-cost particulate matter sensors depends on accurate conversion of sensor output (e.g., voltage) into gravimetric-equivalent mass concentration, typically using a calibration procedure. This study evaluates two important sources of variability that lead to error in estimating gravimetric-equivalent mass concentration: the temporal changes in sensor calibration and the spatial and temporal variability in gravimetric correction factors. A 40-node sensor network was deployed in a heavy vehicle manufacturing facility for 8 months. At a central location in the facility, particulate matter was continuously measured with three sensors of the network and a traditional, higher-cost photometer, determining the calibration slope and intercept needed to translate sensor output to photometric-equivalent mass concentration. Throughout the facility, during three intensive sampling campaigns, respirable mass concentrations were measured with gravimetric samplers and photometers to determine correction factors needed to adjust photometric-equivalent to gravimetric-equivalent mass concentration. Both field-determined sensor calibration slopes and intercepts were statistically different than those estimated in the laboratory (α = 0.05), emphasizing the importance of aerosol properties when converting voltage to photometric-equivalent mass concentration and the need for field calibration to determine slope. Evidence suggested the sensors’ weekly field calibration slope decreased and intercept increased, indicating the sensors were deteriorating over time. The mean correction factor in the cutting and shot blasting area (2.9) was substantially and statistically lower than that in the machining and welding area (4.6; p = 0.01). Therefore, different correction factors should be determined near different occupational processes to accurately estimate particle mass concentrations.
An Incremental Dimensionality Reduction Method for Visualizing Streaming Multidimensional Data
Creators: name: Fujiwara, Takanori
name: Chou, Jia-Kai
name: Shilpika
name: Xu, Panpan
name: Ren, Liu
name: Ma, Kwan-Liu
Publisher: name: arXiv
Year: 2019
Subjects: subject: Graphics (cs.GR)
subject: Human-Computer Interaction (cs.HC)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: I.3.8

description: Dimensionality reduction (DR) methods are commonly used for analyzing and visualizing multidimensional data. However, when data is a live streaming feed, conventional DR methods cannot be directly used because of their computational complexity and inability to preserve the projected data positions at previous time points. In addition, the problem becomes even more challenging when the dynamic data records have a varying number of dimensions as often found in real-world applications. This paper presents an incremental DR solution. We enhance an existing incremental PCA method in several ways to ensure its usability for visualizing streaming multidimensional data. First, we use geometric transformation and animation methods to help preserve a viewer's mental map when visualizing the incremental results. Second, to handle data dimension variants, we use an optimization method to estimate the projected data positions, and also convey the resulting uncertainty in the visualization. We demonstrate the effectiveness of our design with two case studies using real-world datasets.
description: This is the author's version of the article that has been published in IEEE Transactions on Visualization and Computer Graphics. The final version of this record is available at: 10.1109/TVCG.2019.2934433
Additional file 3 of How time horizons of autocrats impact health expenditure: a mixed methods research
Creators: name: Yan, Huang-Ting
name: Lin, Yu-Chun
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Computational Biology

description: Additional file 3. Supplementary Figure 1. Trends in Health Expenditure: More Predictors. Supplementary Figure 2. Trends in Health Expenditure: The Leave-one-out Estimates. Supplementary Figure 3. Placebo Armed Conflict-Trends in Health Expenditure: Actual Country vs. Synthetic Country. Supplementary Figure 4. Ratio of Pre-treatment RMSPE to Post-treatment RMSPE: Chad and Control Countries. Supplementary Figure 5. Health Expenditure Gap: Actual Country versus Synthetic Country. Supplementary Figure 6. Authoritarian Time Horizon and Health Expenditure, 1995-2010. Supplementary Figure 7. Authoritarian Time Horizon and Health Expenditure, 1995-2010. Supplementary Figure 8. Authoritarian Time Horizon and Health Expenditure, 1995-2010. Supplementary Figure 9. Authoritarian Time Horizon and Health Expenditure, 1995-2010. Supplementary Figure 10. IV Analysis: The Coefficient Plot of Predicted Regime Duration, 1995-2010.
Study of the Two-Dimensional Frustrated J1-J2 Model with Neural Network Quantum States
Creators: name: Choo, Kenny
name: Neupert, Titus
name: Carleo, Giuseppe
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The use of artificial neural networks to represent quantum wave-functions has recently attracted interest as a way to solve complex many-body problems. The potential of these variational parameterizations has been supported by analytical and numerical evidence in controlled benchmarks. While approaching the end of the early research phase in this field, it becomes increasingly important to show how neural-network states perform for models and physical problems that constitute a clear open challenge for other many-body computational methods. In this paper we start addressing this aspect, concentrating on a presently unsolved model describing two-dimensional frustrated magnets. Using a fully convolutional neural network model as a variational ansatz, we study the frustrated spin-1/2 J1-J2 Heisenberg model on the square lattice. We demonstrate that the resulting predictions for both ground-state energies and properties are competitive with, and often improve upon, existing state-of-the-art methods. In a relatively small region in the parameter space, corresponding to the maximally frustrated regime, our ansatz exhibits comparatively good but not best performance. The gap between the complexity of the models adopted here and those routinely adopted in deep learning applications is, however, still substantial, such that further improvements in future generations of neural-network quantum states are likely to be expected.
Odontoscelis (Odontoscelis) fuliginosa
Creators: name: Dursun, A.
name: Fent, M.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Scutelleridae
Odontoscelis
Odontoscelis fuliginosa

description: Odontoscelis (Odontoscelis) fuliginosa (LINNAEUS 1761)
M a t e r i a l: loc. 34, 2.
F u t t e r p f l a n z e n: Verschiedene Bodenpflanzen.
description: Published as part of Dursun, A. & Fent, M., 2010, Systematische und faunistische Untersuchungen über die Überfamilie Pentatomoidea (Insecta, Heteroptera) aus dem Kelkit-Tal der Türkei, pp. 587-598 in Linzer biologische Beiträge 42 (1) on page 590, DOI: 10.5281/zenodo.5332773
Chiral 4-O-acylterpineol as transdermal permeation enhancers: insights of the enhancement mechanisms of a transdermal enantioselective delivery system for flurbiprofen
Creators: name: Chu, Tianzhe
name: Wang, Chunyan
name: Wang, Jing
name: Wang, Heping
name: Geng, Dandan
name: Wu, Chensi
name: Zhao, Linlin
name: Zhao, Ligang
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: In order to devise more effective penetration enhancers, 4-O-acylterpineol derivatives which were expected to be hydrolyzed into nontoxic metabolites by esterase in the living epidermis, were synthesized from 4-terpineol (4-TER) enantiomers and straight chain fatty acids. Their promoting activities on the SR-flurbiprofen and its enantiomers were tested across full-thickness rabbit skin, as well as to correlate under in vitro and in vivo conditions. The permeation studies indicated that both d-4-O-acylterpineol and l-4-O-acylterpineol had significant enhancing effects, interestingly, d-4-O-aclyterpineol had higher enhancing effects than l-4-O-aclyterpineol with the exception of d-4-methyl-1-(1-methylethyl)-3-cyclohexen-1-yl octadec-9-enoate (d-4-T-dC18). The mechanism of 4-O-acylterpineol facilitating the drug penetration across the skin was confirmed by Attenuated total reflection-Fourier transformed infrared spectroscopy (ATR-FTIR) and molecular simulation. The mechanism of penetration enhancers promoting drug release was explored by the in vitro release experiment. Finally, a relative safety skin irritation of enhancers was also investigated by in vivo histological evaluation. The present research suggested that d-4-O-aclyterpineol and l-4-O-aclyterpineol could significantly promote the penetration of SR-flurbiprofen and its enantiomers both in vitro and in vivo, with the superiorities of high flux and low dermal toxicity.
Elevated serum ferritin level effectively discriminates severity illness and liver injury of coronavirus disease 2019 pneumonia
Creators: name: Cao, Peng
name: Wu, Yuanjue
name: Wu, Sanlan
name: Wu, Tingting
name: Zhang, Qilin
name: Zhang, Rui
name: Wang, Zhao
name: Zhang, Yu
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Virology

description: Ferritin is a hepatic protein that plays vital roles in diagnosing and predicting diseases, but its potential in coronavirus disease 2019 (COVID-19) remains unknown. We collected clinical records from 79 COVID-19 patients at Wuhan Union hospital (China). Spearman’s correlation analysis, receiver operating characteristic (ROC) curve and Kaplan–Meier survival curves were employed. Patients with elevated ferritin levels had a higher incidence of severity illness (50.0 vs 2.9%) and liver injury (52.3 vs 20.0%) when compared with patients with normal ferritin levels (p < 0.05). Ferritin could effectively identify the severity of illness (ROC area 0.873) and liver injury (ROC area 0.752). The elevated ferritin group showed longer viral clearance time (median 16 vs 6 days, p < 0.001) and in-hospital length (median 18 vs 10 days, p < 0.001). It suggests that ferritin could act as an easy-to-use tool to identify liver injury and severity illness and predict the prognosis of COVID-19 patients. Intensive surveillance is necessary for patients with abnormal ferritin levels.
Cryptaciura rotundiventris
Creators: name: Merz, B.
name: Kofler, A.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Tephritidae
Cryptaciura
Cryptaciura rotundiventris

description: Cryptaciura rotundiventris (FALLÉN 1814)
M a t e r i a l: Osttirol: Lavant 30.6.1994; Leisach: Angerlehauser Waldweg am rechten Drauufer 12.7.2006.
B e m e r k u n g e n Die Larven leben als Blattminierer in verschiedenen Umbelliferen. Die Art ist in Nord-, Mittel- und Osteuropa sowie den Pyrenäen bekannt. An den Fundstellen werden meistens nur Einzeltiere gesammelt.
description: Published as part of Merz, B. & Kofler, A., 2008, Fruchtfliegen aus Osttirol und Kärnten (Österreich) (Diptera: Tephritidae), pp. 1211-1224 in Linzer biologische Beiträge 40 (2) on page 1213, DOI: 10.5281/zenodo.5430623
Σχεδιασμός και ανάπτυξη μίας μορφολογικής βάσης δεδομένων: Η βάση MORILAN
Creators: name: Τσιμπούρης, Χάρης
name: Ανδρέου, Μάριος
name: Κουτσούκος, Νίκος
Publisher: name: Patras Working Papers in Linguistics
Year: 2015
Subjects: βάσεις δεδομένων; εργαλεία ανοικτού κώδικα; Νεοελληνικές διάλεκτοι; μορφολογική επισημείωση

description: Στο παρόν άρθρο παρουσιάζεται η βάση δεδομένων MORILAN, η οποία αναπτύχθηκε στο πλαίσιο του προγράμματος «Μορφολογία και γλωσσική επαφή: Ελληνικές διάλεκτοι σε επαφή με την Τουρκική και την Ιταλική». Η συγκεκριμένη βάση σχεδιάστηκε και υλοποιήθηκε με πρώτο στόχο να αποθηκευτεί και να ταξινομηθεί το διαλεκτικό υλικό που συλλέχθηκε κατά την εκπόνηση του ερευνητικού προγράμματος, αλλά και με απώτερο στόχο να δημιουργηθεί μία σύγχρονη βάση δεδομένων για τη μελέτη και εκπόνηση άλλων προγραμμάτων που σχετίζονται με τις νεοελληνικές διαλέκτους και τη μορφολογία.
description: Patras Working Papers in Linguistics, Τόμ. 4 (2015): Πρόγραμμα Αριστεία: Γλωσσική Επαφή & Μορφολογική Ποικιλία
Μορφολογική Ποικιλία στην Κοινή Νεοελληνική και τις διαλέκτους
Creators: name: Ράλλη, Αγγελική
Publisher: name: Patras Working Papers in Linguistics
Year: 2015
Subjects: ποικιλία; μορφολογία; κλίση; παραγωγή; σύνθεση; γλωσσική επαφή

description: Στην εργασία διερευνάται το φαινόμενο της ποικιλίας στη μορφολογία της Κοινής Νέας Ελληνικής και μερικών από τις πλέον χαρακτηριστικές διαλέκτους της, όπως είναι τα Αϊβαλιώτικα, τα Λεσβιακά, τα Καππαδοκικά, τα Κυπριακά και τα Κατωιταλιώτικα. Μελετώνται οι τομείς της παραγωγής, της σύνθεσης και της κλίσης και εξετάζονται παράγοντες ενδογενείς και εξωγενείς, όπως για παράδειγμα η γλωσσική επαφή, που προκαλούν ή που υποστηρίζουν και ενδυναμώνουν την εμφάνιση ποικιλίας. Αποδεικνύεται ότι η ποικιλία είναι σημαντικό χαρακτηριστικό μιας ζωντανής γλώσσας η οποία υπόκειται στο φυσικό νόμο της εξέλιξης και αλλαγής.
description: Patras Working Papers in Linguistics, Τόμ. 4 (2015): Πρόγραμμα Αριστεία: Γλωσσική Επαφή & Μορφολογική Ποικιλία
Bioassay-guided isolation of cycloartane-type triterpenes, their cytotoxic properties and identification of potential chemical markers from Geniotrigona thoracica propolis
Creators: name: Badiazaman, Ainur Awanis Mohd
name: Aziz, Ahmad Nazif
name: Mohamad, Habsah
name: Mohd, Khamsah Suryati
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Phytochemical investigation through cytotoxicity bioassay-guided isolation of Geniotrigona thoracica propolis led to the identification of five cycloartane-type triterpenes, including mangiferonic acid 1, ambonic acid 2, mangiferolic acid 3, ambolic acid 4 and cycloartenol 5. Their structures were established based on detailed spectroscopic analysis and comparison with literature data. Compounds 1-5 were isolated for the first time in this species. From cytotoxicity MTT assay, compound 3 inhibited the growth of breast (MCF-7) and hepatocellular carcinoma (HepG2) cancer cell lines with IC50 of 5.08 and 4.82 µg/mL, respectively. Cytotoxicity of compounds 1-5 were reported for the first time against HepG2 cancer cell lines. Compounds 1-4 were suggested to serve as main and/or analytical markers for G. thoracica propolis based on HPLC analysis. To our knowledge, this is the first report on the isolation of bioactive constituents and identification of chemical markers for G. thoracica propolis.
title: Inhibition of the Thioredoxin System: Regulation by the Cancer Cell Environment
Creators: name: Bhatia, Maneet
Publisher: name: Griffith University
Year: 2016
Subjects: subject: Tumors
subject: Hypoxia
subject: Thioredoxin system
subject: Hypoxia inducible factor 1 (HIF1)
subject: Cancer cell environment

description: The oxygen environment in tumors is not static and involves constant cycling between hypoxic and re-oxygenation phases, a phenomenon known as intermittent hypoxia. Hypoxic and redox pathways are upregulated in response to intermittent hypoxia. The thioredoxin system, comprised of thioredoxin and thioredoxin reductase, is one of the main antioxidant systems, while hypoxia inducible factor 1 (HIF1) is the major hypoxia responsive system. High levels of both the thioredoxin system proteins and HIF1[alpha] have been correlated with extremely aggressive and highly metastatic tumors. Both these systems have also been linked to development of resistance against anti-cancer therapies. Moreover, HIF1[alpha] is indirectly redox regulated by thioredoxin, suggesting a potential cross-talk between the two systems, which becomes more apparent under intermittent hypoxia. Therefore, an understanding of these two systems under different oxygen conditions occurring in cancers may aid in the designing more effective therapeutics.
Theory and implementation of event-triggered stabilization over digital channels
Creators: name: Khojasteh, Mohammad Javad
name: Hedayatpour, Mojtaba
name: Franceschetti, Massimo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Systems and Control (eess.SY)
subject: Information Theory (cs.IT)
subject: Optimization and Control (math.OC)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: In the context of event-triggered control, the timing of the triggering events carries information about the state of the system that can be used for stabilization. At each triggering event, not only can information be transmitted by the message content (data payload) but also by its timing. We demonstrate this in the context of stabilization of a laboratory-scale inverted pendulum around its equilibrium point over a digital communication channel with bounded unknown delay. Our event-triggering control strategy encodes timing information by transmitting in a state-dependent fashion and can achieve stabilization using a data payload transmission rate lower than what the data-rate theorem prescribes for classical periodic control policies that do not exploit timing information. Through experimental results, we show that as the delay in the communication channel increases, a higher data payload transmission rate is required to fulfill the proposed event-triggering policy requirements. This confirms the theoretical intuition that a larger delay brings a larger uncertainty about the value of the state at the controller, as less timing information is carried in the communication. In addition, our results also provide a novel encoding-decoding scheme to achieve input-to-state practically stability (ISpS) for nonlinear continuous-time systems under appropriate assumptions.
Περιβάλλοντα έντονης γλωσσικής επαφής και δανεισιμότητα λεξικών στοιχείων: δεδομένα από την Griko και την Καππαδοκική
Creators: name: Μαρίνης, Μιχάλης
name: Ράλλη, Αγγελική
Publisher: name: Patras Working Papers in Linguistics
Year: 2015
Subjects: κλίμακες δανεισιμότητας; γλωσσική επαφή; γλωσσικός δανεισμός; Griko; Καππαδοκικά

description: Με αυτή τη συμβολή εξετάζουμε την δανεισιμότητα των διαφόρων λεξικών στοιχείων σε περιβάλλοντα εξαιρετικά έντονης γλωσσικής επαφής. Για τον λόγο αυτό, μελετάμε τον λεξιλογικό δανεισμό δύο ποικιλιών της ελληνικής, η πρώτη εκ των οποίων (Griko) βρίσκεται σε έντονη γλωσσική επαφή με την (ημί)διαχυτική Ιταλορομανική, και η δεύτερη (Καππαδοκική) με την συγκολλητική Τουρκική. Προτείνουμε μία κοινή κλίμακα δανεισιμότητας της μορφής: ονόματα ρήματα επίθετα επιρρήματα. Επιπλέον, διερευνούμε τους παράγοντες οι οποίοι επηρεάζουν την ευκολία δανεισμού των στοιχείων, όπως είναι: (α) η ιδιότητα μίας κατηγορίας να έχει στοιχεία ανοικτής ή κλειστής τάξης, (β) η μορφολογική πολυπλοκότητα κατά την ενσωμάτωση ενός δανείου στην αποδέκτρια γλώσσα, (γ) η ιδιότητα μιας κατηγορίας να έχει καλά οργανωμένα κλιτικά παραδείγματα, (δ) ο ελεύθερος ή δεσμευμένος χαρακτήρας των δανεισμένων στοιχείων, (ε) η τυπολογική απόσταση μεταξύ της γλώσσας δότριας και της γλώσσας αποδέκτριας, (στ) η δομική συμβατότητα μεταξύ των σε επαφή συστημάτων, και (ζ) η ένταση της γλωσσικής επαφής. Αποδεικνύεται ότι δεν είναι όλοι εξίσου καθοριστικοί στην ευκολία δανεισιμότητας των στοιχείων.
description: Patras Working Papers in Linguistics, Τόμ. 4 (2015): Πρόγραμμα Αριστεία: Γλωσσική Επαφή & Μορφολογική Ποικιλία
Open Questions in Cosmic-Ray Research at Ultrahigh Energies
Creators: name: Batista, Rafael Alves
name: Biteau, Jonathan
name: Bustamante, Mauricio
name: Dolag, Klaus
name: Engel, Ralph
name: Fang, Ke
name: Kampert, Karl-Heinz
name: Kostunin, Dmitriy
name: Mostafa, Miguel
name: Murase, Kohta
name: Sigl, Günter
name: Oikonomou, Foteini
name: Olinto, Angela V.
name: Panasyuk, Mikhail I.
name: Taylor, Andrew
name: Unger, Michael
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We review open questions and prospects for progress in ultrahigh-energy cosmic ray (UHECR) research, based on a series of discussions that took place during the `The High-Energy Universe: Gamma-Ray, Neutrino, and Cosmic-ray Astronomy' MIAPP workshop in 2018. Specifically, we overview open questions on the origin of the bulk of UHECRs, the UHECR mass composition, the origin of the end of the cosmic-ray spectrum, the transition from Galactic to extragalactic cosmic rays, the effect of magnetic fields on the trajectories of UHECRs, anisotropy expectations for specific astrophysical scenarios, hadronic interactions, and prospects for discovering neutral particles as well as new physics at ultrahigh energies. We also briefly present upcoming and proposed UHECR experiments and discuss their projected science reach.
description: 47 pages, 17 figures, Review to appear in "Frontiers in Astronomy and Space Science" special issue, "Multi-Messenger Astrophysics: New Windows to the Universe"
Γλωσσική αλλαγή: δάνεια ουσιαστικά στην Επτανησιακή και την Grecanico
Creators: name: Μακρή, Βασιλική
Publisher: name: Patras Working Papers in Linguistics
Year: 2015
Subjects: Επτανησιακά; Grecanico; προσαρμογή ουσιαστικών; άμεση εισαγωγή; εκχώρηση γένους; γλωσσική επαφή

description: Το άρθρο πραγματεύεται την ομοιομορφία που παρατηρείται κατά την ενσωμάτωση δάνειων ουσιαστικών, αντλώντας δεδομένα από δύο διαλεκτικά συστήματα της ελληνικής που έχουν επηρεαστεί από γλωσσική επαφή, δηλαδή τη Grecanico (Griko και Bovese που ομιλούνται στη Νότια Ιταλία) και τα Επτανησιακά (που ομιλούνται στα Ιόνια Νησιά), τα οποία έχουν δεχτεί την επίδραση τοπικών ρομανοϊταλικών ποικιλιών και της Βενετσιάνικης αντίστοιχα, καθώς επίσης και της Ιταλικής. Αποδεικνύεται ότι τα συστήματα στόχοι επιδεικνύουν μια ομοειδή συμπεριφορά κατά την άμεση εισαγωγή δάνειων ουσιαστικών. Υποστηρίζεται ότι γραμματικοί παράγοντες (σημασιολογικοί, μορφολογικοί και φωνολογικοί) συντονισμένα υπαγορεύουν την εκχώρηση γένους στα ρομανοϊταλικά δάνεια των δύο εξεταζόμενων διαλέκτων. Προβάλλεται ο ισχυρισμός ότι η άμεση εισαγωγή ονομάτων από τη Ρομανοϊταλική εξαρτάται από την ενδογλωσσική ιδιότητα του συστήματος στόχου να βασίζεται στο θέμα. Συνολικά, διαφαίνεται ότι ο δανεισμός ουσιαστικών διαφωτίζει τις γενικές αρχές που διέπουν τη διαδικασία εκχώρησης γένους και προσαρμογής δάνειων ουσιαστικών στη γλώσσα στόχο.
description: Patras Working Papers in Linguistics, Τόμ. 4 (2015): Πρόγραμμα Αριστεία: Γλωσσική Επαφή & Μορφολογική Ποικιλία
Eurygaster hottentotta
Creators: name: Dursun, A.
name: Fent, M.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Scutelleridae
Eurygaster
Eurygaster hottentotta

description: Eurygaster hottentotta (FABRICIUS 1775)
M a t e r i a l: loc. 15, 1.
 F u t t e r p f l a n z e n: Poa sp.
V e r b r e i t u n g i n d e r T ü r k e i: Ankara, Bursa (HOBERLANDT 1955), Diyarbak r, Yozgat (ÖNDER et al. 2006).
description: Published as part of Dursun, A. & Fent, M., 2010, Systematische und faunistische Untersuchungen über die Überfamilie Pentatomoidea (Insecta, Heteroptera) aus dem Kelkit-Tal der Türkei, pp. 587-598 in Linzer biologische Beiträge 42 (1) on page 591, DOI: 10.5281/zenodo.5332773
Usability of mepolizumab single-use prefilled autoinjector for patient self-administration
Creators: name: Bernstein, David
name: Pavord, Ian D.
name: Chapman, Kenneth R.
name: Follows, Richard
name: Bentley, Jane H.
name: Pouliquen, Isabelle
name: Bradford, Eric
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology
subject: 60506 Virology

description: Objective: To evaluate usability of mepolizumab as a liquid drug product self-administered via a single-use prefilled autoinjector (AI) by patients with severe eosinophilic asthma (SEA), or their caregivers, in-clinic and at home. Methods: This open-label, single-arm, Phase IIIa study (NCT03099096; GSK ID: 204959) included patients aged ≥12 years with SEA who were either receiving mepolizumab (100 mg subcutaneously [SC]) every 4 weeks (Q4W) for ≥12 weeks before screening or not receiving mepolizumab but met criteria indicative of SEA. Patients/caregivers self-administered mepolizumab (100 mg SC) via an AI Q4W for 12 weeks. The first (Week 0) and third (Week 8) doses were observed in-clinic; the second dose (Week 4) was administered unobserved at home. Primary and secondary endpoints were the proportion of patients who successfully self-administered their third and second doses, respectively (determined by investigator/site staff). Patient experience, mepolizumab trough concentrations, blood eosinophil count (BEC), and safety were also assessed. Results: Of 159 patients/caregivers who self-administered ≥1 dose of mepolizumab, 157 completed the study. Nearly all patients successfully self-administered their third mepolizumab dose in-clinic and second dose at home (≥98% and ≥96%, respectively); this was further confirmed by mepolizumab trough concentrations/BEC. At study end, ≥88% of patients were “very” or “extremely” confident about using the AI correctly. Incidence of on-treatment drug-related adverse events (AEs) was low (3%); no fatal AEs occurred. Conclusions: Patients/caregivers successfully self-administered mepolizumab via the AI both in-clinic and at home; no new safety concerns were identified.
title: Corporate Governance and Firm Risk in Australia
Creators: name: Ali, Searat
Publisher: name: Griffith University
Year: 2017
Subjects: subject: Corporate governance
subject: Risk in business
subject: ASX corporate governance recommendations
subject: Australian Stock Exchange

description: This thesis, structured around three interrelated empirical essays, investigates the relationship of corporate governance with firm risks—default, stock liquidity, downside and upside—for a large sample of Australian listed firms (more than 1,000) over the period from 2001 to 2013. Seven reasons were found that make it imperative to empirically investigate such relationships: (i) a series of corporate collapses in early 2000s (such as HIH and OneTel) due to improper governance structures, (ii) a massive economic and social default cost to the stakeholders, (iii) a proliferated attention of regulators (Australian Securities Exchange [ASX] and related bodies) towards the development of a sound corporate governance environment, (iv) an increased concern of firms to comply with the ASX corporate governance recommendations, (v) an emphasis of the ASX on ‘risk’ while defining good corporate governance, (vi) a small amount of literature relating corporate governance to these risk factors in Australia, and (vii) a different corporate governance environment in Australia (i.e., ‘comply or explain’). The first empirical essay examines: Does corporate governance affect default risk? And does the relationship between corporate governance and default risk depend on growth opportunities and stock liquidity? This study extends the prior literature on the governance–default linkage as this is the first to show that composite corporate governance score is significantly relevant to the reduction of default risk in the Australian context.