cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Leucothoe antarctica Pfeffer 1888
Creators: name: White, Kristine N.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ericales
Ericaceae
Leucothoe
Leucothoe antarctica

description: Leucothoe antarctica Pfeffer, 1888
 Leucothoe antarctica Pfeffer, 1888: 128, pl. 2, fig. 4. — Stebbing, 1906: 168.
 Leucothoe spinicarpa Della Vale, 1893: 653.
 Type locality and specimens. South Georgia. Defective specimen, 5 mm.
 Material examined. No material available for examination. Diagnosis based on description by Pfeffer (1888).
 Diagnosis (sex unknown). Pfeffer’s (1888) original description of Leucothoe antarctica is vague and states that this species is “similar in every respect” to Leucothoe articulosa Montagu.
 Note. The original illustrations were unavailable for viewing. Pending analysis of type or topotypic material, this should not be considered a valid species.
 Female (sexually dimorphic characters). Unknown.
 Habitat. Habitat and depth not reported.
 Host. Unknown.
 Distribution. South Atlantic Ocean: South Georgia (Pfeffer 1888).
description: Published as part of White, Kristine N., 2011, A taxonomic review of the Leucothoidae (Crustacea: Amphipoda) 3078, pp. 1-113 in Zootaxa 3078 (1) on page 42, DOI: 10.11646/zootaxa.3078.1.1, http://zenodo.org/record/5243821
Jets in deep-inelastic scattering at HERA
Creators: name: Wing, M.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Jet cross sections in deep-inelastic scattering over a wide region of phase space have been measured at HERA. These cross section measurements provide a thorough test of the implementation of Quantum Chromodynamics in next-to-leading order (NLO) calculations. They also provide the opportunity to test the consistency of the gluon distribution in the proton as extracted from (mainly) inclusive DIS measurements. Comparison of the cross sections with NLO enables accurate extractions of the strong coupling constant, $α_s$, to be made, several of which are reported here.
description: Talk presented at "New Trends in HERA Physics", Ringberg Workshop, June 2001. 13pages, 12figures
Additional file 7 of Enhancer RNA commits osteogenesis via microRNA-3129 expression in human bone marrow-derived mesenchymal stem cells
Creators: name: Nguyen, Anh Phuong
name: Yamagata, Kaoru
name: Iwata, Shigeru
name: Trimova, Gulzhan
name: Zhang, Tong
name: Shan, Yu
name: Nguyen, Mai-Phuong
name: Sonomoto, Koshiro
name: Nakayamada, Shingo
name: Kato, Shigeaki
name: Tanaka, Yoshiya
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 7: Supplementary Figure S4. All full-length images of Western blotting data. Uncropped full-length images are shown on Figure S4, and the images cropped from the data (n=1) on the Figure S4 are shown on the right side of Fig. 6B. Western blotting was performed one time.
Leucothoe ashleyae Thomas & Klebba 2006
Creators: name: White, Kristine N.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ericales
Ericaceae
Leucothoe
Leucothoe ashleyae

description: Leucothoe ashleyae Thomas & Klebba, 2006
 Leucothoe ashleyae Thomas & Klebba, 2006: 14–16, figs 1–3. — White, 2011: 26, 27, fig. 3.
 Type locality and specimens. Whale Shoals, Belize, 16°45.838'N 88°05.723'W. Holotype, male, 3.8 mm, USNM 1081597; paratypes, male, 4.3 mm, female, 2.9 mm, USNM 1081598.
 Material examined. Unmeasured males and females, USNM 1081597, USNM 1081598, USNM 1081599. Diagnosis based on description by Thomas & Klebba (2006).
 Diagnosis. Gnathopod 1 propodus palm strongly serrate. Gnathopod 2 carpus serrate, expanded distally; propodus palm with two large projections. Epimeron 1 with anteroventral tuft of setae.
 Female (sexually dimorphic characters). Gnathopod 2 carpus anterior margin smooth; propodus with three secondary mediofacial setae, palm smooth.
 Habitat. Coral reefs; 1–20 m.
 Host. Sponges: Callyspongia vaginalis, Amphimedon compressa Duchassaing & Michelotti, 1864, Iotrochota birotulata (Higgin, 1877), Niphates digitalis Lamarck, 1814, N. erecta Duchassaing & Michelotti, 1864, Pseudoceratina crassa (Hyatt, 1875), and Tedania ignis Duchassaing & Michelotti, 1864.
 Distribution. Western Atlantic Ocean: Southeast Florida, Florida Keys (Thomas & Klebba 2006). Caribbean Sea: Belize, Roatan, Panama, Bahamas, Vieques, Puerto Rico (Thomas & Klebba 2006), Panama (White 2011).
description: Published as part of White, Kristine N., 2011, A taxonomic review of the Leucothoidae (Crustacea: Amphipoda) 3078, pp. 1-113 in Zootaxa 3078 (1) on pages 42-43, DOI: 10.11646/zootaxa.3078.1.1, http://zenodo.org/record/5243821
Implementation of cervical cancer prevention services for HIV-infected women in Zambia: Measuring program effectiveness
Creators: name: Stringer, J.S.A.
name: King, K.E.,
name: Hicks, M.L.
name: Mudenda, V.
name: Vermund, S.H.
name: Mkumba, G.
name: Chi, B.H.
name: Mwanahamuntu, M.H.
name: Sahasrabuddhe, V.V.
name: Westfall, A.O.
name: Kapambwe, S.
name: Parham, G.P.
name: Chibwesha, C.
name: Pfaendler, K.S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Background: Cervical cancer kills more women in low-income nations than any other malignancy. A variety of research and demonstration efforts have proven the efficacy and effectiveness of low-cost cervical cancer prevention methods but none in routine program implementation settings of the developing world, particularly in HIV-infected women. Methods: In our public sector cervical cancer prevention program in Zambia, nurses conduct screening using visual inspection with acetic acid aided by digital cervicography. Women with visible lesions are offered same-visit cryotherapy or referred for histologic evaluation and clinical management. We analyzed clinical outcomes and modeled program effectiveness among HIV-infected women by estimating the total number of cervical cancer deaths prevented through screening and treatment. Results: Between 2006 and 2008, 6572 HIV-infected women were screened, 53.6% (3523) had visible lesions, 58.5% (2062) were eligible for cryotherapy and 41.5% (1461) were referred for histologic evaluation. A total of 75% (1095 out of 1462) of patients who were referred for evaluation complied. Pathology results from 65% (715 out of 1095) of women revealed benign abnormalities in 21% (151), cervical intraepithelial neoplasia (CIN) I in 30% (214), CIN 2/3 in 33% (235) and invasive cervical cancer in 16.1% (115, of which 69% were early stage). Using a conditional probability model, we estimated that our program prevented 142 cervical cancer deaths (high/low range: 238-96) among the 6572 HIV-infected women screened, or one cervical cancer death prevented per 46 (corresponding range: 28-68) HIV-infected women screened. Conclusion: Our prevention efforts using setting-appropriate human resources and technology have reduced morbidity and mortality from cervical cancer among HIV-infected women in Zambia. Financial support for implementing cervical cancer prevention programs integrated within HIV/AIDS care programs is warranted. Our prevention model can serve as the implementation platform for future low-cost HPV-based screening methods, and our results mayprovide the basis for comparison of programmatic effectiveness of future prevention efforts.
Changes in the lake thermal and mixing dynamics on the Tibetan Plateau
Creators: name: Wang, Mingda
name: Hou, Juzhi
name: zhu, La
name: Li, Xiumei
name: Liang, Jie
name: Xie, Shuyun
name: Tang, Wenjun
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Physical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The thermal regimes of lakes are important for understanding the functions and services of lake ecosystems. However, continuous lake temperature monitoring across the Tibetan Plateau is sparse, which inhibits verification of the modeling results and also in-depth understanding about the lake thermal and mixing dynamics in this region. Here, we present the results of continuous temperature monitoring of a dimictic lake, Bangong Co, during 2012–2014 and a meromictic lake, Dagze Co, during 2012–2015 to gain insight into the difference between their thermal dynamics and to understand the influencing factors. The results showed that no evident changes in the thermal and mixing regimes were observed at the two lakes during the observational period. However, the thermal structure changed in different hydrological years. The air temperature changes and associated glacier melt possibly contribute to changes in the water temperature for Bangong Co while heat transfer related to wind speed is vital for Dagze Co. An in-depth knowledge necessitates long-term monitoring data to testify the influence of various individual climatic parameters.
Higgs boson pair production via gluon fusion at N$^3$LO in QCD
Creators: name: Chen, Long-Bin
name: Li, Hai Tao
name: Shao, Hua-Sheng
name: Wang, Jian
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present next-to-next-to-next-to-leading order (N$^3$LO) QCD predictions for the Higgs boson pair production via gluon fusion at hadron colliders in the infinite top-quark mass limit. Besides the inclusive total cross sections at various collision energies, we also provide the invariant mass distribution of the Higgs boson pair. Our results show that the N$^3$LO QCD corrections enhance the next-to-next-to-leading order cross section by $3.0\%$ ($2.7\%$) at $\sqrt{s}=13~(100)$ TeV, while the scale uncertainty is reduced substantially below $3\%$ ($2\%$). We also find that a judicious scale choice can significantly improve the perturbative convergence. For the invariant mass distribution, our calculation demonstrates that the N$^3$LO corrections improve the scale dependence but almost do not change the shape.
description: 8 pages, 5 figures, published version in PLB
Covariant Poisson equation with compact Lie algebras
Creators: name: Salmela, Antti
Publisher: name: arXiv
Year: 2002
Subjects: subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 35J05, 35B65, 46E35

description: The covariant Poisson equation for Lie algebra-valued mappings defined in 3-dimensional Euclidean space is studied using functional analytic methods. Weighted covariant Sobolev spaces are defined and used to derive sufficient conditions for the existence and smoothness of solutions to the covariant Poisson equation. These conditions require, apart from suitable continuity, appropriate local integrability of the gauge potentials and global weighted integrability of the curvature form and the source. The possibility of nontrivial asymptotic behaviour of a solution is also considered. As a by-product, weighted covariant generalisations of Sobolev embeddings are established.
description: 31 pages, LaTeX2e
Media Summary (< 100 words) from Fluid dynamics of cerebrospinal fluid flow in perivascular spaces
Creators: name: Thomas, John H.
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: 110601 Biomechanics
subject: FOS: Health sciences
subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering
subject: 29903 Medical Physics
subject: FOS: Physical sciences

description: The flow of cerebrospinal fluid along perivascular spaces (PVSs) is an important part of the brain’s system for delivering nutrients and eliminating metabolic waste products (such as amyloid-β), and it also offers a pathway for the delivery of therapeutic drugs to the brain parenchyma. Recent experimental results have resolved several important questions about this flow, setting the stage for advances in our understanding of the fluid dynamics of the flow. This review summarizes the new experimental evidence and provides a critical evaluation of previous fluid-dynamic models of flows in PVSs. The review also discusses some basic fluid-dynamic concepts relevant to these flows, including the combined effects of diffusion and advection in clearing solutes from the brain.
EC3-A modern telecommunications matrix for cervical cancer prevention in Zambia
Creators: name: Stringer, J.S.A.
name: Sahasrabuddhe, V.V.
name: Hicks, M.L.
name: Parham, G.P.
name: Pfaendler, K.S.
name: Chibwesha, C.
name: Kapambwe, S.
name: Myung, D.
name: Mwanahamuntu, M.H.
name: Mwanza, B.
name: Mkumba, G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Objectives.: Low physician density, undercapacitated laboratory infrastructures, and limited resources are major limitations to the development and implementation of widely accessible cervical cancer prevention programs in sub-Saharan Africa. Materials and methods.: We developed a system operated by nonphysician health providers that used widely available and affordable communication technology to create locally adaptable and sustainable public sector cervical cancer prevention program in Zambia, one of the world's poorest countries. Results.: Nurses were trained to perform visual inspection with acetic acid aided by digital cervicography using predefined criteria. Electronic digital images (cervigrams) were reviewed with patients, and distance consultation was sought as necessary. Same-visit cryotherapy or referral for further evaluation by a gynecologist was offered. The Zambian system of "electronic cervical cancer control" bypasses many of the historic barriers to the delivery of preventive health care to women in low-resource environments while facilitating monitoring, evaluation, and continued education of primary health care providers, patient education, and medical records documentation. Conclusions.: The electronic cervical cancer control system uses appropriate technology to bridge the gap between screening and diagnosis, thereby facilitating the conduct of "screen-and-treat" programs. The inherent flexibility of the system lends itself to the integration with future infrastructures using rapid molecular human papillomavirus-based screening approaches and wireless telemedicine communications.
Myths and misconceptions about cervical cancer among Zambian women: rapid assessment by peer educators.
Creators: name: Mwanahamuntu, M.
name: Kapambwe, S.
name: Pfaendler, K.
name: Sahasrabuddhe, V.
name: Stringer, J.
name: Parham, G.
name: Chirwa, S.
name: Mkumba, G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: OBJECTIVE: To make a rapid assessment of the common myths and misconceptions surrounding the causes of cervical cancer and lack of screening among unscreened low-income Zambian women. METHODS: We initiated a door-to-door community-based initiative, led by peer educators, to inform unscreened women about the existence of a new see-and-treat cervical cancer prevention program. During home visits peer educators posed the following two questions to women: 1. What do you think causes cervical cancer? 2. Why haven't you been screened for cervical cancer? The most frequent types of responses gathered in this exercise were analyzed thematically. RESULTS: Peer educators contacted over 1100 unscreened women over a period of two months. Their median age was 33 years, a large majority (58%) were not educated beyond primary school, over two-thirds (71%) did not have monthly incomes over 500,000 Zambian Kwacha (US$100) per month, and just over half (51%) were married and cohabiting with their spouses. Approximately 75% of the women engaged in discussions had heard of cervical cancer and had heard of the new cervical cancer prevention program in the local clinic. The responses of unscreened low-income Zambian women to questions posed by peer educators in urban Lusaka reflect the variety of prevalent 'folk' myths and misconceptions surrounding cervical cancer and its prevention methods. CONCLUSION: The information in our rapid assessment can serve as a basis for developing future educational and intervention campaigns for improving uptake of cervical cancer prevention services in Zambia. It also speaks to the necessity of ensuring that programs addressing women's reproductive health take into account societal inputs at the time they are being developed and implemented. Taking a community-based participatory approach to program development and implementation will help ensure sustainability and impact.
Leucothoe assimilis J. L. Barnard 1974
Creators: name: White, Kristine N.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ericales
Ericaceae
Leucothoe
Leucothoe assimilis

description: Leucothoe assimilis J.L. Barnard, 1974
 Leucothoe assimilis J.L. Barnard, 1974b: 82–85, figs 51, 52. — Ledoyer, 1984: 80, 81, fig. 38. — Lowry & Stoddart, 2003: 155.
 Type locality and specimens. Western Port, Victoria. Holotype, male, 9.5 mm, NMV.
 Material examined. No material available for examination. Diagnosis based on description by J. L. Barnard (1974).
 Diagnosis. Maxilla 1 palp constricted. Gnathopod 2 carpus with large subdistal tooth. Epimeron 1 with anteroventral tuft of setae. Epimeron 3 sinuous with simple cusp. Telson with facial setae.
 Note. Leucothoe assimilis Ledoyer, 1984 differs from Barnard’s description in lacking the subdistal tooth on gnathopod 2 carpus and epimeron 3 lacking a cusp. Examination of material is necessary to determine if Ledoyer’s report is actually Leucothoe assimilis.
 Female (sexually dimorphic characters). Gnathopod 2 propodus mediofacial setal row displaced to midline and reaching 0.8 of propodus length. Juveniles without posteroventral cusp on epimeron 3.
 Habitat. Among bryozoans; 40 m (reported as 22 fthm).
 Host. Ascidian: Pyura praeputialis (Heller, 1878) and sponges.
 Distribution. Pacific Ocean: Western Port, Victoria, Australia (J.L. Barnard 1974b; Lowry & Stoddart 2003); New Caledonia: Noumea (Ledoyer 1984).
description: Published as part of White, Kristine N., 2011, A taxonomic review of the Leucothoidae (Crustacea: Amphipoda) 3078, pp. 1-113 in Zootaxa 3078 (1) on page 43, DOI: 10.11646/zootaxa.3078.1.1, http://zenodo.org/record/5243821
Charge equilibration in integer and fractional quantum Hall edge channels in a generalized Hall-bar device
Creators: name: Lin, Chaojing
name: Eguchi, Ryota
name: Hashisaka, Masayuki
name: Akiho, Takafumi
name: Muraki, Koji
name: Fujisawa, Toshimasa
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Charge equilibration between quantum-Hall edge states can be studied to reveal geometric structure of edge channels not only in the integer quantum Hall (IQH) regime but also in the fractional quantum Hall (FQH) regime particularly for hole-conjugate states. Here we report on a systematic study of charge equilibration in both IQH and FQH regimes by using a generalized Hall bar, in which a quantum Hall state is nested in another quantum Hall state with different Landau filling factors. This provides a feasible way to evaluate equilibration in various conditions even in the presence of scattering in the bulk region. The validity of the analysis is tested in the IQH regime by confirming consistency with previous works. In the FQH regime, we find that the equilibration length for counter-propagating $δν$ = 1 and $δν$ = -1/3 channels along a hole-conjugate state at Landau filling factor $ν$ = 2/3 is much shorter than that for co-propagating $δν$ = 1 and $δν$ = 1/3 channels along a particle state at $ν$ = 4/3. The difference can be associated to the distinct geometric structures of the edge channels. Our analysis with generalized Hall bar devices would be useful in studying edge equilibration and edge structures.
description: 10 pages, 6 figures
Quark mass density- and temperature- dependent model for bulk strange quark matter
Creators: name: al, Yun Zhang et.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: It is shown that the quark mass density-dependent model can not be used to explain the process of the quark deconfinement phase transition because the quark confinement is permanent in this model. A quark mass density- and temperature-dependent model in which the quark confinement is impermanent has been suggested. We argue that the vacuum energy density B is a function of temperature. The dynamical and thermodynamical properties of bulk strange quark matter for quark mass density- and temperature-dependent model are discussed.
description: 6 Pages, 5 Figures. To be published on Phys. Rev. C
Management of cryotherapy-ineligible women in a "screen-and-treat" cervical cancer prevention program targeting HIV-infected women in Zambia: Lessons from the field
Creators: name: Stringer, J.S.A.
name: Pfaendler, K.S.
name: Mwanahamuntu, M.H.
name: Sahasrabuddhe, V.V.
name: Parham, G.P.
name: Mudenda, V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Objective: We demonstrate the feasibility of implementing a referral and management system for cryotherapy-ineligible women in a "screen-and-treat" cervical cancer prevention program targeting HIV-infected women in Zambia. Methods: We established criteria for patient referral, developed a training program for loop electrosurgical excision procedure (LEEP) providers, and adapted LEEP to a resource-constrained setting. Results: We successfully trained 15 nurses to perform visual inspection with acetic acid (VIA) followed by immediate cryotherapy. Women with positive tests but ineligible for cryotherapy were referred for further evaluation. We trained four Zambian physicians to evaluate referrals, perform punch biopsy, LEEP, and manage intra-operative and post-operative complications. From January 2006 through October 2007, a total of 8823 women (41.5% HIV seropositive) were evaluated by nurses in outlying prevention clinics; of these, 1477 (16.7%) were referred for physician evaluation based on established criteria. Of the 875 (59.2% of 1147 referred) that presented for evaluation, 748 (8.4% of total screened) underwent histologic evaluation in the form of punch biopsy or LEEP. Complications associated with LEEP included anesthesia reaction (n = 2) which spontaneously resolved, intra-operative (n = 12) and post-operative (n = 2) bleeding managed by local measures, and post-operative infection (n = 12) managed with antibiotics. Conclusion: With adaptations for a resource-constrained environment, we have demonstrated that performing LEEP is feasible and safe, with low rates of complications that can be managed locally. It is important to establish referral and management systems using LEEP-based excisional evaluation for women with cryotherapy-ineligible lesions in VIA-based "screen-and-treat" protocols nested within HIV-care programs in resource-constrained settings.
Integrating cervical cancer prevention in HIV/AIDS treatment and care programmes
Creators: name: Mwanahamuntu, M.H.
name: Parham, G.P.
name: Sahasrabuddhe, V.V.
name: Stringer, J.S.A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Peckham and Hann’s call for integrating cervical cancer prevention as part of broader sexual and reproductive health prevention services is especially relevant to sub-Saharan Africa where both cervical cancer and sexually transmitted infections, especially HIV/AIDS, are widely prevalent.
Correlation Between Cataract Surgery and Anxiety Levels in Senile Cataract Patients
Creators: name: Bayurini Dian Hapsari
name: Rodiah Rahmawaty Lubis
name: Sihombing, Yan Pieter
Publisher: name: figshare
Year: 2019
Subjects: subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences

description: Background: Cataract may cause decrease of vision due to clouding of the lens. Poor vision and surgery caused by cataract may also result in an increased risk of anxiety and depression. Purposes: to determine the correlation between cataract surgery and anxiety levels in patients who will undergo cataract surgery. Methods: This is a cross-sectional study design and conducted according to the Declaration of Helsinki and was approved by the local ethical committee amongst the senile cataract patients. The data were analyzed by using spearman's rank correlation test to find the correlation between cataract surgery and anxiety level. The sampling method was purposive sampling. The Hamilton Anxiety Rating Scale (HAM-A) or HRS-A (Hamilton Rating Scale for Anxiety) was used to rate the severity of patient's anxiety. Results: A number of 63 cataract patients who will undergo cataract surgery were included for analysis and have been interviewed to get the anxiety level by using HAM-A. The most age of patient was 50-59 years old (29;46%). The stage of the senile cataract was mostly the mature stage of about 36 patients (57.1%). From HAM-A questionnaire the most anxiety level of senile cataract patients who will be operated was moderate level (49;77,8%). Spearman's rank correlation test with SPSS 17 obtained p = 0.002 with sig (2-tailed) value < 0.05 and correlation coefficient r = 0, 383. Conclusion: There is a correlation between cataract surgery and anxiety levels in senile cataract patients who will undergo cataract surgery.
Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins
Creators: name: Alzahofi, Noura
name: Welz, Tobias
name: Robinson, Christopher L.
name: Page, Emma L.
name: Briggs, Deborah A.
name: Stainthorp, Amy K.
name: Reekes, James
name: Elbe, David A.
name: Straub, Felix
name: Kallemeijn, Wouter W.
name: Tate, Edward W.
name: Goff, Philip S.
name: Sviderskaya, Elena V.
name: Cantero, Marta
name: Montoliu, Lluis
name: Nedelec, Francois
name: Miles, Amanda K.
name: Bailly, Maryse
name: Kerkhoff, Eugen
name: Hume, Alistair N.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/80
/631/80/128
/631/80/128/1276
/13/1
/13/89
/13/44
/13/95
/13/106
/13/109
/14
/14/19
/14/28
/14/33
/82/29
/96/63
article

description: Abstract: Cell biologists generally consider that microtubules and actin play complementary roles in long- and short-distance transport in animal cells. On the contrary, using melanosomes of melanocytes as a model, we recently discovered that the motor protein myosin-Va works with dynamic actin tracks to drive long-range organelle dispersion in opposition to microtubules. This suggests that in animals, as in yeast and plants, myosin/actin can drive long-range transport. Here, we show that the SPIRE-type actin nucleators (predominantly SPIRE1) are Rab27a effectors that co-operate with formin-1 to generate actin tracks required for myosin-Va-dependent transport in melanocytes. Thus, in addition to melanophilin/myosin-Va, Rab27a can recruit SPIREs to melanosomes, thereby integrating motor and track assembly activity at the organelle membrane. Based on this, we suggest a model in which organelles and force generators (motors and track assemblers) are linked, forming an organelle-based, cell-wide network that allows their collective activity to rapidly disperse the population of organelles long-distance throughout the cytoplasm.
Radiative Decay of the ψ(2S) into Two Pseudoscalar Mesons
Creators: name: BES Collaboration
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Radiative decays of the radially excited charmonium resonance, ψ(2S), into ππ, K Kbar and ηηfinal states have been measured in a sample of 3.96 * 10^6 ψ(2S) events collected by the BES collaboration. The branching ratios B(ψ(2S) -> γf_{2}(1270)) = (2.27 +- 0.26 +- 0.39) * 10^{-4} and B(ψ(2S) -> γf_0(1710)) * B(f_0(1710) -> K^+ K^-) = (5.59 +- 1.12 +- 0.93) * 10^{-5} are obtained. When compared to the corresponding radiative J/ψdecays, the observed ψ(2S) radiative decay rates into γf_2(1270) and γf_0(1710) are consistent with the 15% rule.
description: 7 pages, 5 figures
HRE 2020-0598 Research Data: Interview Guide
Creators: name: Quigley, Niamh
Publisher: name: Zenodo
Year: 2021
Subjects: open access experiences
humanities
interview guide

description: This Word document is the semi-structured interview guide for Niamh Quigley's Master of Information Management thesis at Curtin University, Perth, Australia titled 'Engagement with open access among Curtin University humanities researchers: Exploring the perceptions of, and barriers to publishing OA' Six interviews took place from November 2020 - January 2021 (five interviews conducted in person at Curtin University, Perth, and one online interview). The six interviewees are experienced researchers in the Faculty of Humanties at Curtin University, and consented to sharing their deidentified data as a publicly available dataset (https://10.5281/zenodo.4774447). The project supervisor was Dr Hollie White, Lecturer, School of Media, Creative Arts and Social Inquiry. This research project has approval from the Curtin University Human Research Ethics Office (HRE 2020-0598).
Sonographic Correlation of Placenta Previa with Pregnancy Outcomes After 24 Weeks of Gestation
Creators: name: Bashir, Tania
name: Raham Bacha
name: Gilani, Syed Amir
name: Shehzadi Irum
name: Mehreen Fatima S
name: S. Muhammad Yousaf Farooq
name: Javaid, Babar
name: Kausar, Shazia
Publisher: name: figshare
Year: 2019
Subjects: subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences

description: Placenta typically discoid in shape and echogenic (hyperechoic) structure visible on ultrasound. Placenta may be extend to the lateral wall of uterus but normally lies along the anterior and posterior wall of the uterus. The thickness of placenta is 2.0cm to 2.5cm and measuring diameter 22cm. In various times placenta abnormally located along the internal cervical os of uterus which may be partially or fully covered the os that’s called placenta previa. Prevalence of placenta previa occurs in approximately 5 per 1000 pregnancies. Prevalence of Placenta previa is rising as a result of increasing rates of LSCS (Lower segment cesarean section). Placenta previa leads many adverse outcomes during pregnancy for both fetus and maternal so it is require follow up scan at term. Objective: The main objective is to estimate the sonographic correlation of placenta previa with pregnancy outcomes after 24weeks of gestation. Methodology: A cross sectional analytical study conducted at Tertiary care Teaching Services Hospital Lahore. Maternal diagnosed with placenta previa after 24 weeks of gestation included and also only singleton pregnancies. Maternal observed with follow up scans throughout term and analyzed perinatal outcomes. GE Logiq S8 Ultrasound machine, with 3.5MHz convex probe used for the evaluation of patients. Results: Total 77 patients. We observed among maternal with high grade (type three and four) placenta previa are highly significant and associated with outcome cesarean deliveries. Then those minimum maternal with low grade (type one and two) placenta previa are not highly significant. Another result we find out those maternal who have previous history of Lower segment cesarean section associated with placenta previa.
Gene regulatory network inference from sparsely sampled noisy data
Creators: name: Aalto, Atte
name: Viitasaari, Lauri
name: Ilmonen, Pauliina
name: Mombaerts, Laurent
name: Gonçalves, Jorge
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/553/2714
/631/553/2700
/631/553/2393
/631/553/2699
/129
/119
/141
article

description: Abstract: The complexity of biological systems is encoded in gene regulatory networks. Unravelling this intricate web is a fundamental step in understanding the mechanisms of life and eventually developing efficient therapies to treat and cure diseases. The major obstacle in inferring gene regulatory networks is the lack of data. While time series data are nowadays widely available, they are typically noisy, with low sampling frequency and overall small number of samples. This paper develops a method called BINGO to specifically deal with these issues. Benchmarked with both real and simulated time-series data covering many different gene regulatory networks, BINGO clearly and consistently outperforms state-of-the-art methods. The novelty of BINGO lies in a nonparametric approach featuring statistical sampling of continuous gene expression profiles. BINGO’s superior performance and ease of use, even by non-specialists, make gene regulatory network inference available to any researcher, helping to decipher the complex mechanisms of life.
Modelling of processes in nerve fibres at the interface of physiology and mathematics
Creators: name: Engelbrecht, Jüri
name: Tamm, Kert
name: Peets, Tanel
Publisher: name: arXiv
Year: 2019
Subjects: subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: The in silico simulations are widely used in contemporary systems biology including the analysis of nerve pulse propagation. As known from numerous experiments, the propagation of an action potential is accompanied by mechanical and thermal effects. This calls for an analysis at the interface of physics, physiology and mathematics. In this paper, the background of the model equations governing the effects in nerve fibres is analysed from a physical viewpoint and then discussed how to unite them into a system by using the coupling forces. The leading hypothesis associates the coupling to the changes of variables, not to their values or amplitudes. This hypothesis models actually the physiological mechanisms of energy transductions in a fibre. The general assumptions in modelling the processes and the properties of the coupled system of equations are described. The dimensionless mathematical model which couples the action potential with mechanical waves together with temperature effects is presented in the Appendix. This model generates an ensemble of waves including the electrical signal and mechanical and thermal effects.
Orbifolded SU(7) and unification of families
Creators: name: Hwang, Kyuwan
name: Kim, Jihn E.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A 5D SU(7) family unification model with two spinor representations of SO(14) is presented. The fifth dimension is compactified on $S^1/Z_2\times Z_2'$. The orbifolding is used to obtain 4D SO(10) chiral fermions. The 4D grand unification group is the flipped $SU(5)\times U(1)$. The doublet-triplet splitting through the missing partner mechanism is achieved. Also, fermion mass matrices are considered.
description: LaTeX file of 11 pages
Pathogen genomic surveillance of typhoidal Salmonella infection in adults and children reveals no association between clinical outcomes and infecting genotypes
Creators: name: Britto, Carl D.
name: Mathias, Sitarah
name: Bosco, Ashish
name: Dyson, Zoe A.
name: Dougan, Gordon
name: Raveendran, Savitha
name: Abin, V. L.
name: Jose, Sanju
name: Nagaraj, Savitha
name: Holt, Kathryn E.
name: Pollard, Andrew J.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Short Report
Enteric fever
Typhi
Paratyphi
Clinical features
H58
India

description: Funder: Rhodes Scholarships; doi: http://dx.doi.org/10.13039/501100000697
description: Funder: Bill and Melinda Gates Foundation; doi: http://dx.doi.org/10.13039/100000865
description: Abstract: Background: India is endemic for enteric fever, and it is not known whether the variations in clinical manifestations between patients are due to host, environmental or pathogen factors. Blood culture surveillance was conducted at St. John’s Medical College Hospital, Bangalore, between July 2016 and June 2017. Clinical, laboratory and demographic data were collected from each case, and bacterial isolates were subjected to whole genome sequencing. Comparative analysis between adults and paediatric patients was carried out to ascertain differences between adult and paediatric disease. Results: Among the 113 cases of blood culture-confirmed enteric fever, young adults (16–30 years) and children < 15 years accounted for 47% and 37% of cases, respectively. Anaemia on presentation was seen in 46% of cases, and 19% had an abnormal leucocyte count on presentation. The majority received treatment as inpatients (70%), and among these, adults had a significantly longer duration of admission when compared with children (p = 0.002). There were atypical presentations including arthritis, acute haemolysis and a case of repeated typhoid infection with two separate S. Typhi genotypes. There was no association between infecting genotype/serovar and treatment status (outpatient vs inpatient), month of isolation, duration of admission, patient age (adult or child), antimicrobial susceptibility, Widal positivity or haematologic parameters. Conclusions: Amidst the many public health concerns of South India, enteric fever continues to contribute substantially to hospital burden with non-specific as well as uncommon clinical features in both paediatric and adult populations likely driven by host and environmental factors. Robust clinical surveillance as well monitoring of pathogen population structure is required to inform treatment and preventive strategies.
Leucothoe atosi Bellan-Santini 2007
Creators: name: White, Kristine N.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ericales
Ericaceae
Leucothoe
Leucothoe atosi

description: Leucothoe atosi Bellan-Santini, 2007
 Leucothoe atosi Bellan-Santini, 2007: 573–575, figs 7, 8.
 Type locality and specimens. Mid–Atlantic Ridge, Menez Gwen site, 37°50.52'N 31°32.23'W. Holotype, female, 5 mm, MNHN M –7465; unmeasured paratypes, MNHN Am–7466.
 Material examined. No material available for examination. Diagnosis based on description by Bellan-Santini (2007).
 Diagnosis (female). Eyes absent. Gnathopod 1 basis with setose posterior margin; propodus and carpus elongate; dactylus short. Gnathopod 2 carpus short. Pereopods 5–7 bases narrowly expanded.
 Male (sexually dimorphic characters). Unknown.
 Habitat. Habitat not reported; 850 m.
 Host. Unknown.
 Distribution. Atlantic Ocean: Mid–Atlantic Ridge, Menez Gwen, Azores (Bellan-Santini 2007).
description: Published as part of White, Kristine N., 2011, A taxonomic review of the Leucothoidae (Crustacea: Amphipoda) 3078, pp. 1-113 in Zootaxa 3078 (1) on page 43, DOI: 10.11646/zootaxa.3078.1.1, http://zenodo.org/record/5243821
The Configuration of the Perivascular System Transporting Macromolecules in the CNS (PREPRINT)
Creators: name: Durcanova, Beata
name: Appleton, Janine
name: Gurijala, Nyshidha
name: Belov, Vasily
name: Giffenig, Pilar
name: Moeller, Elisabeth
name: Hogan, Matthew
name: Lee, Fredella
name: Papisov, Mikhail
Publisher: name: arXiv
Year: 2019
Subjects: subject: Tissues and Organs (q-bio.TO)
subject: FOS: Biological sciences

description: Large blood vessels entering the CNS are surrounded by perivascular spaces that communicate with the cerebrospinal fluid and, at their termini, with the interstitial space. Solutes and particles can translocate along these perivascular conduits, reportedly in both directions. Recently, this prompted a renewed interest in the intrathecal therapy delivery route for CNS-targeted therapeutics. However, the extent of the CNS coverage by the perivascular system is unknown, making the outcome of drug administration to the CSF uncertain. We traced the translocation of model macromolecules from the CSF into the CNS of rats and non-human primates. Conduits transporting macromolecules were found to extend throughout the parenchyma from both external and internal (fissures) CNS boundaries, excluding ventricles, in large numbers, on average ca. 40 channels per mm2 in rats and non-human primates. The high density and depth of extension of the perivascular channels suggest that the perivascular route can be suitable for delivery of therapeutics to parenchymal targets throughout the CNS.
description: 16 pages, 6 figures, 61 references
Hermitizing the HAL QCD potential in the derivative expansion
Creators: name: Aoki, Sinya
name: Iritani, Takumi
name: Yazaki, Koichi
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A formalism is given to hermitize the HAL QCD potential, which needs to be non-hermitian except the leading order (LO) local term in the derivative expansion as the Nambu-Bethe-Salpeter (NBS) wave functions for different energies are not orthogonal to each other. It is shown that the non-hermitian potential can be hermitized order by order to all orders in the derivative expansion. In particular, the next-to-leading order (NLO) potential can be exactly hermitized without approximation. The formalism is then applied to a simple case of $ΞΞ(^{1}S_{0}) $ scattering, for which the HAL QCD calculation is available to the NLO. The NLO term gives relatively small corrections to the scattering phase shift and the LO analysis seems justified in this case. We also observe that the local part of the hermitized NLO potential works better than that of the non-hermitian NLO potential. The hermitian version of the HAL QCD potential is desirable for comparing it with phenomenological interactions and also for using it as a two-body interaction in many body systems.
description: 20 pages, 8 figures, appendix added with some other modifications for the published version
Hopping induced ground-state magnetism in 6H perovskite iridates
Creators: name: Nag, A.
name: Bhowal, S.
name: Sala, M. Moretti
name: Efimenko, A.
name: Dasgupta, I.
name: Ray, S.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Investigation of elementary excitations has advanced our understanding of many-body physics governing most physical properties of matter. Recently spin-orbit excitons have drawn much attention, whose condensates near phase transitions exhibit Higgs mode oscillations, a long-sought physical phenomenon [Nat. Phys. {\bf 13}, 633 (2017)]. These critical transition points resulting from competing spin-orbit coupling (SOC), local crystalline symmetry and exchange interactions, are not obvious in Iridium based materials, where SOC prevails in general. Here, we present results of resonant inelastic x-ray scattering on a spin-orbital liquid Ba$_3$ZnIr$_2$O$_9$ and three other 6H-hexagonal perovskite iridates which show magnetism, contrary to non-magnetic singlet ground state expected due to strong SOC. Our results show that substantial hopping between closely placed Ir$^{5+}$ ions within Ir$_2$O$_9$ dimers in these 6H-iridates, modifies spin-orbit coupled states and reduces spin-orbit excitation energies. Here, we are forced to use at least a two-site model, to match the excitation spectrum going in line with the strong intra-dimer hopping. Apart from SOC, low energy physics of iridates is thus critically dependent on hopping, and may not be ignored even for systems having moderate hopping, where the excitation spectra can be explained using an atomic model. SOC which is generally found to be 0.4-0.5~eV in iridates, is scaled in effect down to $\sim$0.26~eV for the 6H-systems, sustaining the hope to achieve quantum criticality by tuning Ir-Ir separation.
description: 12 Pages, Main text has 4 figures, SI which is added at the end of the main text has 5 figures and two tables
Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription
Creators: name: Oikawa, Mami
name: Simeone, Angela
name: Hormanseder, Eva
name: Teperek, Marta
name: Gaggioli, Vincent
name: O’Doherty, Alan
name: Falk, Emma
name: Sporniak, Matthieu
name: D’Santos, Clive
name: Franklin, Valar Nila Roamio
name: Kishore, Kamal
name: Bradshaw, Charles R.
name: Keane, Declan
name: Freour, Thomas
name: David, Laurent
name: Grzybowski, Adrian T.
name: Ruthenburg, Alexander J.
name: Gurdon, John
name: Jullien, Jerome
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/136/2086
/631/136/2434/1822
/45/15
/45/29
/45/23
/13/1
/38/22
/45/77
/64
/64/114
article

description: Abstract: Sperm contributes genetic and epigenetic information to the embryo to efficiently support development. However, the mechanism underlying such developmental competence remains elusive. Here, we investigated whether all sperm cells have a common epigenetic configuration that primes transcriptional program for embryonic development. Using calibrated ChIP-seq, we show that remodelling of histones during spermiogenesis results in the retention of methylated histone H3 at the same genomic location in most sperm cell. This homogeneously methylated fraction of histone H3 in the sperm genome is maintained during early embryonic replication. Such methylated histone fraction resisting post-fertilisation reprogramming marks developmental genes whose expression is perturbed upon experimental reduction of histone methylation. A similar homogeneously methylated histone H3 fraction is detected in human sperm. Altogether, we uncover a conserved mechanism of paternal epigenetic information transmission to the embryo through the homogeneous retention of methylated histone in a sperm cells population.
SnR Evaluation Framework
Creators: name: Aumayr, Georg
name: Ferner, Pia
name: Prinzellner, Yvonne
name: Dumitrascu, Alexandru
name: González, Marta Burgos
name: Bertram, Svenja
name: Guerri, Marco
name: Panzariuc, Gabriela
name: Santorinaios, Christodoulos
Publisher: name: Zenodo
Year: 2021
Subjects: Evaluation Framework

description: Purpose of this SnR evaluation framework is to provide guidance on a structured evaluation process for all use cases to evaluate all technology components developed under the SnR project. In order to achieve this, a set of KPIs has been formulated for each individual technology component. Subsequently an iterative definition and selection process has been established to identify relevant KPIs for each use case. The evaluation criteria take account of the technologies on the one hand, but on the other hand also consider context specific needs of each use case. The deliverable takes stock of the objectives of all use cases that have already been defined in the respective pilot plans. These are important to understand the different contexts in which the technologies will be tested and from which different needs and requirements for the different technologies may result. This Framework intends to provide guidance for the overall set up of the evaluation process applying a common approach. However, the variety of technologies and use cases makes it impossible to define one process that fits every situation and hence needs to leave room for some flexibility in adapting the evaluation tools, while still leaving possibilities for comparison. D8.9 elaborates on the development process of the SnR evaluation framework, under involvement of end-users and technical partners, also providing indications for further research and next steps to be taken for the evaluation phase of the project. Furthermore, it details the data collection methodologies, listing and summarizing all relevant methods needed to plan and execute the trials. These have also been matched with the preliminary set of KPIs for the technology components which have been selected for use cases. The deliverable concludes with a checklist for all use case organizers in order to ensure that planning prior, during and after completion of the use cases is timely and adequate. The framework will be core for this next phase of the project when it comes to testing the technologies in the use cases. Considerations on the evaluation need to be incorporated in the overall planning and set up of the use cases to have a clear understanding of the tasks that need to be performed and by whom, to have high quality data for the evaluation.