Additional file 4 of Risk factors for metachronous colorectal cancer and advanced neoplasia following primary colorectal cancer: a systematic review and meta-analysis
Creators: name: Zhang, Ye
name: Karahalios, Amalia
name: Aung, Ye Kyaw
name: Win, Aung Ko
name: Boussioutas, Alex
name: Jenkins, Mark A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 4: Figure S1. Forest plot of the association between age and metachronous advanced neoplasia and metachronous colorectal cancer. (a) including all selected studies (b) sensitivity analysis of excluding one study reported the opposite association. All relative risks (RRs) were calculated through dose-response analysis. CI, confidence interval. Figure S2. Forest plot of the association between sex and metachronous advanced neoplasia and metachronous colorectal cancer. (a) including all selected studies (b) sensitivity analysis of excluding unadjusted effect estimates. RR, relative risk; CI, confidence interval. Figure S3. Forest plot of the association between family history and metachronous advanced neoplasia and metachronous colorectal cancer. (a) including all selected studies (b) sensitivity analysis of excluding unadjusted effect estimates. RR, relative risk; CI, confidence interval. Figure S4. Forest plot presenting meta-analysis for the association between type 2 diabetes (vs no) and metachronous advanced neoplasia and metachronous colorectal cancer. RR, relative risk; CI, confidence interval. Figure S5. Forest plot presenting meta-analysis for the association between hypertension (vs no) and metachronous advanced neoplasia. RR, relative risk; CI, confidence interval. Figure S6. Forest plot presenting meta-analysis for the association between body mass index (&gt; = 25 kg/m2 vs &lt; 25 kg/m2) and metachronous advanced neoplasia. RR, relative risk; CI, confidence interval. Figure S7. Forest plot presenting meta-analysis for the association between aspirin use and metachronous advanced neoplasia and metachronous colorectal cancer. (a) including all selected studies (b) sensitivity analysis of excluding unadjusted effect estimates. RR, relative risk; CI, confidence interval. Figure S8. Forest plot presenting meta-analysis for the association between current smoking and metachronous advanced neoplasia. RR, relative risk; CI, confidence interval. Figure S9. Forest plot presenting meta-analysis for the association between presence of synchronous advanced lesions and metachronous advanced neoplasia and metachronous colorectal cancer. (a) including all selected studies (b) sensitivity analysis of excluding unadjusted effect estimates. RR, relative risk; CI, confidence interval. Figure S10. Forest plot presenting meta-analysis for the association between location of first colorectal cancer (distal vs proximal) and metachronous advanced neoplasia and metachronous colorectal cancer. (a) including all selected studies (b) sensitivity analysis of excluding unadjusted effect estimates. RR, relative risk; CI, confidence interval. Figure S11. Forest plot presenting meta-analysis for the association between advanced TNM stage and metachronous advanced neoplasia. RR, relative risk; CI, confidence interval.