cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
TRNA mutations that affect decoding fidelity deregulate development and the proteostasis network in zebrafish
Creators: name: Reverendo, Marisa
name: Carreto, Laura
name: Gatti, Evelina
name: Pierre, Philippe
name: Moura, Gabriela R
name: Soares, Ana R
name: Pereira, Patrícia M
name: Ferreira, Violeta
name: Santos, Manuel A
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Developmental Biology
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biochemistry

description: Mutations in genes that encode tRNAs, aminoacyl-tRNA syntheases, tRNA modifying enzymes and other tRNA interacting partners are associated with neuropathies, cancer, type-II diabetes and hearing loss, but how these mutations cause disease is unclear. We have hypothesized that levels of tRNA decoding error (mistranslation) that do not fully impair embryonic development can accelerate cell degeneration through proteome instability and saturation of the proteostasis network. To test this hypothesis we have induced mistranslation in zebrafish embryos using mutant tRNAs that misincorporate Serine (Ser) at various non-cognate codon sites. Embryo viability was affected and malformations were observed, but a significant proportion of embryos survived by activating the unfolded protein response (UPR), the ubiquitin proteasome pathway (UPP) and downregulating protein biosynthesis. Accumulation of reactive oxygen species (ROS), mitochondrial and nuclear DNA damage and disruption of the mitochondrial network, were also observed, suggesting that mistranslation had a strong negative impact on protein synthesis rate, ER and mitochondrial homeostasis. We postulate that mistranslation promotes gradual cellular degeneration and disease through protein aggregation, mitochondrial dysfunction and genome instability.
РОЛЬ ВЫСШЕГО ОБРАЗОВАНИЯ В ФОРМИРОВАНИИ ЧЕЛОВЕЧЕСКОГО КАПИТАЛА
Creators: name: Анна Николаевна Беляева
Publisher: name: Вестник Московского университета МВД России
Year: 2020
Subjects: высшее образование
человеческий потенциал
человеческий капитал
экономическое развитие
общество

description: Исследуется высшее образование как составляющая развития человеческого потенциала страны. Отмечено, что мировая экономическая система характеризуется новой парадигмой экономического развития на основе значительного уменьшения роли материально-ресурсных компонентов общественного производства и повышения его интеллектуального компонента. Определено, что устойчивое экономическое развитие на основе инновационной модели развития требует подготовки и задействования человеческого потенциала, превращение его в весомый фактор общественного производства. В постиндустриальной экономике умения и способности человека, весь его интеллектуальный, психофизический и социокультурный потенциал, а также духовное состояние, превращаются в главный производственный ресурс
ПОДХОДЫ К ПОНИМАНИЮ СУЩНОСТИ ПУБЛИЧНЫХ УСЛУГ
Creators: name: Ольга Владимировна Курбатова
Publisher: name: Вестник Московского университета МВД России
Year: 2020
Subjects: публичное администрирование
публичный интерес
государственное управление
публичная власть
сервисное государство
социальное государство
публичная услуга
государственная услуга

description: Анализируются подходы к пониманию сущности публичных услуг в контексте теорий сервисного государства и позитивного государственного управления. Подчеркивается, что отождествление публичных услуг с государственными неоправдано; они должны рассматриваться как целое и часть. Показана взаимосвязь категорий «публичная услуга» и «публичный интерес».
РАЗВИТИЕ ОТДЕЛЬНЫХ ФИНАНСОВЫХ ИНСТРУМЕНТОВ БЮДЖЕТНОГО ПЛАНИРОВАНИЯ
Creators: name: Ольга Борисовна Буздалина
Publisher: name: Вестник Московского университета МВД России
Year: 2020
Subjects: внутреннее экономическое развитие государства
экономический рост
государственные программы
экономический потенциал
программно-целевое управление

description: Одной из неотъемлемых частей экономической политики государства является бюджетная политика, которая непосредственно отражает структуру финансовых взаимоотношений с институтами и экономическими субъектами. Она занимает ведущее место в экономической политике страны, формируя как налоговую, так и инвестиционную политику, отражая государственные интересы и функции, которые требуются для решения рационального размещения бюджетных средств, во многом определяя экономический курс развития страны. В ходе анализе были выявлены элементы системы эффективности государственной программы: результат, степень его достижения; полнота использования бюджетных ассигнований, выделенных для реализации государственной программы; эффективность расходования средств на реализацию госпрограмм; выполнение запланированных мероприятий.
Impact of filaments on galaxy cluster properties in The Three Hundred simulation
Creators: name: Santoni, Sara
name: De Petris, Marco
name: Ferragamo, Antonio
name: Yepes, Gustavo
name: Cui, Weiguang
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Galaxy clusters and their filamentary outskirts reveal useful laboratories to test cosmological models and investigate Universe composition and evolution. Their environment, in particular the filaments of the Cosmic Web to which they are connected, plays an important role in shaping the properties of galaxy clusters. In this project, we analyse the gas filamentary structures present in 324 regions of The Three Hundred hydrodynamical simulation extracted with the DisPerSE filament finder. We estimate the number of gas filaments globally connected to several galaxy clusters, i.e. the connectivity k, with a mass range of $10^{13} \leq M_{200} \, h^{-1} \, M_{\odot} \leq 10^{15} $ at redshift $z=0$. We study the positive correlation between the connectivity and mass of galaxy clusters. Moreover, we explore the impact of filaments on the dynamical state of clusters, quantified by the degree of relaxation parameter $χ$.
description: to appear in Proc. of the mm Universe 2023 conference, Grenoble (France), June 2023, published by F. Mayet et al. (Eds), EPJ Web of conferences, EDP Sciences
Trial-based cost-effectiveness of abatacept for rheumatoid arthritis patients in Italy
Creators: name: J Gaultney
name: M Benucci
name: S Iannazzo
name: C Nappi
name: K Sion
name: FJ Sabater
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Introduction: Rheumatoid arthritis (RA) is a chronic, inflammatory disorder leading to disability and reduced quality of life. Effective treatment is a significant economic burden on the Italian healthcare system. Economic models in RA are commonly based on indirect treatment comparisons. Methods: This study assessed the cost–effectiveness of abatacept relative to adalimumab for RA in Italy based on a head-to-head trial by means of a cost–consequence analysis. Results: Health benefits based on the most stringent efficacy criteria were in favor of abatacept compared to adalimumab. Rates for more costly adverse events were higher for adalimumab compared to abatacept, which was reflected in the lower costs for abatacept (-€237,246 or -€237per patient). Conclusion: The health economic value of abatacept compared with adalimumab from the perspective of the Italian NHS depends on the choice of health outcome. Health gains with abatacept were generally based on more stringent criteria and lower total costs.
ПОРЯДОК И ОСОБЕННОСТИ НАЗНАЧЕНИЯ ПЕНСИЙ ГРАЖДАНАМ, ПРИБЫВШИМ НА ПОСТОЯННОЕ МЕСТО ЖИТЕЛЬСТВА В РОССИЙСКУЮ ФЕДЕРАЦИЮ ИЗ ГОСУДАРСТВ–УЧАСТНИКОВ СНГ, В ПОДРАЗДЕЛЕНИЯХ ПЕНСИОННОГО ОБСЛУЖИВАНИЯ МВД РОССИИ
Creators: name: Евгения Владимировна Новикова
name: Алина Андреевна Попова
Publisher: name: Вестник Московского университета МВД России
Year: 2020
Subjects: пенсионное обеспечение
выслуга лет
внутренний финансовый контроль

description: Подчеркивается стабильно высокий интерес пенсионеров органов внутренних дел государств–участников Содружества независимых государств к назначению пенсий по законам и нормам Российской Федерации в связи с переездом на постоянное место жительства. Рассматриваются порядок и особенности назначением пенсий на территории Российской Федерации указанной категории лиц.
СОВРЕМЕННОЕ ОБРАЗОВАНИЕ: НОВАЦИИ И ТРАДИЦИИ
Creators: name: Виталий Юрьевич Бельский
name: Андрей Львович Золкин
Publisher: name: Вестник Московского университета МВД России
Year: 2020
Subjects: психология
образование
традиции
новации
обучение
воспитание

description: Анализируется проблема соотношения традиций и новаций в образовании. Образование понимается как институт воспроизводства культурного пространства инновационных и традиционных аспектов общественного развития. Цивилизационная стратегия рассматривается как основная методология построения культурного пространства современного отечественного образования. Делаются выводы о качественной специфике модели образования в силу ее зависимости от структурных и ценностных особенностей российской цивилизации.
ПРОБЛЕМЫ РАЗВИТИЯ КОММУНИКАТИВНОЙ КОМПЕТЕНТНОСТИ СОТРУДНИКОВ ОВД
Creators: name: Айгуль Вильевна Гайнуллина
Publisher: name: Вестник Московского университета МВД России
Year: 2020
Subjects: коммуникативная компетентность
профессионально-психологическая подготовленность
общение
сотрудники ОВД
граждане

description: Рассмотрено понятие коммуникативной компетентности в психологической науке, проанализированы взгляды юридических психологов на структуру коммуникативной компетентности, исследованы некоторые особенности профессионально-психологической подготовленности сотрудников ОВД к общению с гражданами; разработаны рекомендации по ее совершенствованию.
Local RNA flexibility perturbation of the IRES element induced by a novel ligand inhibits viral RNA translation
Creators: name: Grandas, Anna
name: Pedroso, Enrique
name: Martínez-Salas, Encarnación
name: Lozano, Gloria
name: Trapote, Alejandro
name: Ramajo, Jorge
name: Elduque, Xavier
name: Robles, Jordi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Cancer
subject: Chemistry
subject: Molecular Biology
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: The internal ribosome entry site (IRES) element located at the 5´untranslated genomic region of various RNA viruses mediates cap-independent initiation of translation. Picornavirus IRES activity is highly dependent on both its structural organization and its interaction with host factors. Small molecules able to interfere with RNA function are valuable candidates for antiviral agents. Here we show that a small molecule based on benzimidazole (IRAB) inhibited foot-and-mouth disease virus (FMDV) IRES-dependent protein synthesis in cells transfected with infectious RNA leading to a decrease of the virus titer, which was higher than that induced by a structurally related benzimidazole derivative. Interestingly, IRAB preferentially inhibited IRES-dependent translation in cell free systems in a dose-dependent manner. RNA structural analysis by SHAPE demonstrated an increased local flexibility of the IRES structure upon incubation with IRAB, which affected 3 stem-loops (SL) of domain 3. Fluorescence binding assays conducted with individual aminopurine-labeled oligoribonucleotides indicated that the SL3A binds IRAB (EC50 18 μM). Taken together, the results derived from SHAPE reactivity and fluorescence binding assays suggested that the target site of IRAB within the FMDV IRES might be a folded RNA structure that involves the entire apical region of domain 3. Our data suggest that the conformational changes induced by this compound on a specific region of the IRES structure which is essential for its activity is, at least in part, responsible for the reduced IRES efficiency observed in cell free lysates and, particularly, in RNA-transfected cells.
ПСИХОЛОГО-СОЦИОЛОГИЧЕСКОЕ ИССЛЕДОВАНИЕ СОВРЕМЕННОГО СОСТОЯНИЯ ПСИХОЛОГИЧЕСКОГО ОБЕСПЕЧЕНИЯ ОРГАНОВ ВНУТРЕННИХ ДЕЛ
Creators: name: Дмитрий Владимирович Деулин
name: Ирина Викторовна Усачева
Publisher: name: Вестник Московского университета МВД России
Year: 2020
Subjects: психологическое сопровождение
профессиональный психологический отбор
личные и деловые качества
административно-кадровые
вопросы технического обслуживания
нормативное правовое обеспечение
развитие методического обеспечения

description: Рассматриваются проблемы психологического сопровождения сотрудников подразделениями психологической работы в органах внутренних дел. На основе научных методов выявляются и констатируются задачи, решение которых способствует совершенствованию профессионального психологического отбора в органах внутренних дел. Материалы подталкивают к осмыслению современного состояния уровня психологического обеспечения в правоохранительной системе Министерства внутренних дел России. Среди наиболее острых вопросов, на которые обращают внимание авторы статьи, можно выделить административно-кадровые вопросы, вопросы технического обслуживания, нормативное правовое обеспечение, проблема развития методического обеспечения. Целью статьи является оказание помощи всем заинтересованным лицам в комплектовании органов внутренних дел высококвалифицированными кадрами с высоким уровнем психологической устойчивости к профессиональной деятельности и сформированной профессиональной компетентностью.
Sugar and artificially sweetened soda consumption linked to hypertension: A systematic review and meta-analysis
Creators: name: Wisit Cheungpasitporn
name: Charat Thongprayoon
name: Edmonds, Peter J.
name: Narat Srivali
name: Patompong Ungprasert
name: Wonngarm Kittanamongkolchai
name: Erickson, Stephen B.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Background/objectives: The risk of hypertension (HTN) in patients who regularly drink soda is controversial. The objective of this meta-analysis was to assess the associations between consumption of sugar and artificially sweetened soda and HTN. Methods: A literature search was performed using MEDLINE, EMBASE and Cochrane Database of Systematic Reviews from inception through January 2015. Studies that reported relative risks, odd ratios or hazard ratios comparing the risk of HTN in patients consuming a significant amount of either sugar or artificially sweetened soda versus those who did not consume soda were included. Pooled risk ratios (RR) and 95% confidence interval (CI) were calculated using a random-effect, generic inverse variance method. Results: Eight studies were included in our analysis to assess the association between consumption of sugar-sweetened soda and HTN. The pooled RR of HTN in patients consuming sugar-sweetened soda was 1.12 (95% CI, 1.03–1.23). Four studies were selected to assess the association between consumption of artificially sweetened soda and HTN. The pooled RR of HTN in patients consuming artificially sweetened soda was 1.15 (95% CI, 1.11–1.19). Conclusions: Our study demonstrates statistically significant associations between both sugar and artificially sweetened soda consumption and HTN. This finding may impact clinical management and primary prevention of HTN.
Corruption and Electoral Support for New Political Parties in Central and Eastern Europe
Creators: name: Engler, Sarah
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: Neuroscience

description: More than 20 years after the collapse of the Soviet Union, the electoral volatility in Central and Eastern Europe (CEE) is still remarkably high. A considerable part of the volatility derives from the votes for new political parties, since they are very often on the winning side of elections. This article examines corruption as a potential determinant of their electoral support. It argues that the effect of corruption is twofold: on the one hand, the historically derived corruption level reduces the electoral support for new political parties due to strong clientelist structures that bind the electorate to the established parties. On the other hand, an increase in perceived corruption above the traditional corruption level leads to a loss of trust in the political elite and therefore boosts the electoral support for new competitors. A statistical analysis of all democratic elections in CEE between 1996 and 2013 confirms these two counteracting effects.
Optimising Distributions with Natural Gradient Surrogates
Creators: name: So, Jonathan
name: Turner, Richard E.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Natural gradient methods have been used to optimise the parameters of probability distributions in a variety of settings, often resulting in fast-converging procedures. Unfortunately, for many distributions of interest, computing the natural gradient has a number of challenges. In this work we propose a novel technique for tackling such issues, which involves reframing the optimisation as one with respect to the parameters of a surrogate distribution, for which computing the natural gradient is easy. We give several examples of existing methods that can be interpreted as applying this technique, and propose a new method for applying it to a wide variety of problems. Our method expands the set of distributions that can be efficiently targeted with natural gradients. Furthermore, it is fast, easy to understand, simple to implement using standard autodiff software, and does not require lengthy model-specific derivations. We demonstrate our method on maximum likelihood estimation and variational inference tasks.
К ВОПРОСУ О ЦЕННОСТНЫХ ОРИЕНТАЦИЯХ УСЛОВНО ОСУЖДЕННЫХ НА ПРИМЕРЕ ВОЦЕРКОВЛЕНИЯ
Creators: name: Дмитрий Сергеевич Мельниченко
Publisher: name: Вестник Московского университета МВД России
Year: 2020
Subjects: воцерковление
ценностные ориентации
религия
условно осужденные

description: В современных реалиях развития уголовно-исполнительной системы Российской Федерации в ценностных ориентациях осужденных растет роль приобщения к религии, углубления своих знаний в области религиозных познаний различных конфессий в определенных группах лиц, отбывающих уголовные наказания. Рассматривается приобщение к православному вероисповеданию лиц, содержащихся в местах лишения свободы в сравнении с осужденными, отбывающими наказание без лишения свободы и состоящими на учете в УИИ.
ТИПИЧНЫЕ ПСИХИЧЕСКИЕ СОСТОЯНИЯ В ПРОФЕССИОНАЛЬНОЙ ДЕЯТЕЛЬНОСТИ СОТРУДНИКОВ ПАТРУЛЬНО-ПОСТОВОЙ СЛУЖБЫ ПОЛИЦИИ
Creators: name: Кристина Дмитриевна Пашенцева
Publisher: name: Вестник Московского университета МВД России
Year: 2020
Subjects: профессиональная деятельность
психологические особенности
психическое состояние
типичные психические состояния

description: Рассматриваются психологические особенности профессиональной деятельности патрульно-постовой службы полиции, влияющие на возникновение типичных психических состояний.
Emergent symmetries and Interactions: An isolated fixed point Vs a manifold of strongly interacting fixed points
Creators: name: Zhou, Fei
Publisher: name: arXiv
Year: 2023
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: In this article, we study conditions of continuous emergent symmetries in gapless states, either as topological quantum critical points (TQCPs) or a stable phase with protecting symmetries and connections to smooth deformations of the gapped states around. We illustrate that for a wide class of gapless states that can be associated with fully-isolated scale invariant fixed points, there shall always be emergent continuous symmetries that are directly related to smooth deformations of gapped states with symmetries lower than the protecting ones $G_p$. For a 3D TQCP in DIII classes with $G_p=Z^T_2$, $U_{EM}=U(1)$ and $N_f=\frac{1}{2}$ fermions but without charge $U(1)$ symmetry, we explicitly construct a corresponding boundary representation based on a $4D$ topological state with lattice symmetry $H=Z^T_2 \ltimes U(1)$ and $N_f={1}$ fermions. Although emergent continuous symmetries appear to be robust at weakly interacting TQCPs, we further show the breakdown of such one-to-one correspondence between deformations of gapped states and emergent continuous symmetries when gapless states become strongly interacting. In a strongly interacting limit, gapless states can be represented by a smooth manifold of conformal-field-theory fixed points rather than a fully isolated one. A smooth manifold of strong coupling fixed points hinders emergence of a continuous emergent symmetry in the strongly interacting gapless limit, as deformations no longer leave a gapless state or a TQCP invariant, unlike in the more conventional weakly interacting case. This typically reduces continuous emergent symmetries to a discrete symmetry originating from duality transformations under the protection symmetry $G_p$.
description: 27 pages, 5 figures; comments are welcome; published version
ARRIVE Checklist: Effectiveness of forest honey (Apis dorsata) as therapy for ovarian failure that caused malnutrition
Creators: name: Safitri, Erma
name: Purnobasuki, Hery
name: Purnama, Muhammad Thohawi Elziyad
name: Chhetri, Shekhar
Publisher: name: figshare
Year: 2022
Subjects: subject: 70201 Animal Breeding
subject: FOS: Animal and dairy science

description: ARRIVE checklist during a study performed.
ПСИХОЛОГИЯ ПОТЕРИ — ФИЗИОГЕНИЯ. ЭФФЕКТИВНОСТЬ ИГЛОРЕФЛЕКСОТЕРАПИИ ПРИ ФИЗИОГЕННЫХ ПОТЕРЯХ ГОМЕОСТАЗА ФУНКЦИОНАЛЬНЫХ СИСТЕМ У ВОЕННОСЛУЖАЩИХ, СОТРУДНИКОВ УГОЛОВНО-ИСПОЛНИТЕЛЬНОЙ СИСТЕМЫ В ЭКСТРЕМАЛЬНЫХ УСЛОВИЯХ ЖИЗНЕДЕЯТЕЛЬНОСТИ
Creators: name: Владимир Иванович Серов
Publisher: name: Вестник Московского университета МВД России
Year: 2020
Subjects: психология потери
саногенез
физиогения
функциональная система
физиогенные потери
физиологическая коррекция
иглорефлексотерапия
гомеостаз
оксибионт
экстремальные условия жизнедеятельности

description: Психология потери с развитием физиогении функциональной системы купируется активацией механизма саногенеза иглорефлексотерапией и определяется через эффективность коррекции физиогенных потерь, в частности, психоэмоционального шока, обезболивания у военнослужащих, сотрудников уголовно-исполнительной системы в экстремальных условиях жизнедеятельности. Иглорефлексотерапия — единственный метод, который эффективен, прост и экономичен в боевых (полевых) условиях по быстрому восстановлению функций психики и сомы, ликвидации болевого синдрома. Дезадаптация военнослужащего, сотрудника уголовно-исполнительной системы активирует его психическое состояние и одну из 12 функциональных систем. При физиогении изменение гомеостаза 12 функциональных систем, регулирующих все функции, увеличивало нервную импульсацию от функциональных систем в головной мозг, нарушая висцеро-церебральное и психосоматическое равновесие. В итоге менялись физиологические параметры деятельности нейронов, что составляло физиологический механизм отклонений в психической деятельности и при прямой и обратной связи создавало единство изменений в психике и соме. Психический акт сопровождался физико-химическими сдвигами до квантового уровня, который, меняя гомеостаз (постоянство) метаболических процессов, развертывался в микроинтервалах времени и пространства, составляя внутреннее единство субъективного и объективного, социального, психического и физиологического. При острых изменениях психики сдвиги происходили в наиболее реактивных системах организма с декомпенсацией функциональной системы, составляющей Locus minoris resistentiae — место наименьшего сопротивления. Физиогенные потери блокировались физиологической защитой, но с переходом в пограничное психическое состояние. Для возврата из пограничного состояния в пределы нормы диагностировали выделившуюся функциональную систему и иглорефлексотерапией снижали ее активность.
BLIS-Net: Classifying and Analyzing Signals on Graphs
Creators: name: Xu, Charles
name: Goldman, Laney
name: Guo, Valentina
name: Hollander-Bodie, Benjamin
name: Trank-Greene, Maedee
name: Adelstein, Ian
name: De Brouwer, Edward
name: Ying, Rex
name: Krishnaswamy, Smita
name: Perlmutter, Michael
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Graph neural networks (GNNs) have emerged as a powerful tool for tasks such as node classification and graph classification. However, much less work has been done on signal classification, where the data consists of many functions (referred to as signals) defined on the vertices of a single graph. These tasks require networks designed differently from those designed for traditional GNN tasks. Indeed, traditional GNNs rely on localized low-pass filters, and signals of interest may have intricate multi-frequency behavior and exhibit long range interactions. This motivates us to introduce the BLIS-Net (Bi-Lipschitz Scattering Net), a novel GNN that builds on the previously introduced geometric scattering transform. Our network is able to capture both local and global signal structure and is able to capture both low-frequency and high-frequency information. We make several crucial changes to the original geometric scattering architecture which we prove increase the ability of our network to capture information about the input signal and show that BLIS-Net achieves superior performance on both synthetic and real-world data sets based on traffic flow and fMRI data.
Closed FRW holography: A time-dependent ER=EPR realization
Creators: name: Franken, Victor
name: Partouche, Hervé
name: Rondeau, François
name: Toumbas, Nicolaos
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We extend a recent de Sitter holographic proposal and entanglement entropy prescription to generic closed FRW cosmologies in arbitrary dimensions, and propose that for large classes of bouncing and Big Bang/Big Crunch cosmologies, the full spacetime can be encoded holographically on two holographic screens, associated to two antipodal observers. In the expanding phase, the two screens lie at the apparent horizons. In the contracting phase, there is an infinite number of possible trajectories of the holographic screens, which can be grouped in equivalence classes. In each class the effective holographic theory can be derived from a pair of ``parent'' screens on the apparent horizons. A number of cases including moduli dominated cosmologies escape our discussion, and it is expected that two antipodal observers and their associated screens do not suffice to reconstruct these cosmologies. The leading contributions to the entanglement entropy between the screens arise from a minimal extremal trapped or anti-trapped surface lying in the region between them. This picture entails a time-dependent realization of the ER=EPR conjecture, where an effective geometrical bridge connecting the screens via the minimal extremal surface emerges from entanglement. For the Big Crunch contracting cases, the screens disentangle and the geometrical bridge closes off when the minimal extremal trapped sphere hits the Big Crunch singularity at a finite time before the collapse of the Universe. Semiclassical, thermal corrections are incorporated in the cases of radiation dominated cosmologies.
description: 60 pages + 3 appendices, 20 figures. Published version
(Social) Trouble on the Road: Understanding and Addressing Social Discomfort in Shared Car Trips
Creators: name: Bremers, Alexandra
name: Friedman, Natalie
name: Lee, Sam
name: Wu, Tong
name: Laurier, Eric
name: Jung, Malte
name: Ortiz, Jorge
name: Ju, Wendy
Publisher: name: arXiv
Year: 2023
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Unpleasant social interactions on the road can negatively affect driving safety. At the same time, researchers have attempted to address social discomfort by exploring Conversational User Interfaces (CUIs) as social mediators. Before knowing whether CUIs could reduce social discomfort in a car, it is necessary to understand the nature of social discomfort in shared rides. To this end, we recorded nine families going on drives and performed interaction analysis on this data. We define three strategies to address social discomfort: contextual mediation, social mediation, and social support. We discuss considerations for engineering and design, and explore the limitations of current large language models in addressing social discomfort on the road.
description: 13 pages, ACM CUI'24
A systematic review to understand the social implications of digital technologies in community-based biodiversity projects
Creators: name: Ganesh, Sangita
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Nature and Society Relations
subject: Environmental Policy
subject: Human Geography
subject: FOS: Social and economic geography
subject: Community-based Research
subject: Life Sciences
subject: Public Affairs, Public Policy and Public Administration
subject: Economics
subject: Environmental Studies
subject: Biodiversity
subject: Social and Behavioral Sciences
subject: Sociology
subject: FOS: Sociology
subject: Geography

description: This research seeks to understand how digital technologies (mobile phones, applications, websites, and social media) are currently adopted in community-based biodiversity projects for environmental and animal monitoring globally, and to understand current discussions on the social implications of their adoption.
Orientation dependence of optical activity in light scattering by nanoparticle clusters
Creators: name: Fazel-Najafabadi, A
name: Auguié, Baptiste
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2022
Subjects: Uncategorized

description: The optical properties of nanoparticle clusters vary with the spatial arrangement of the constituent particles, but also the overall orientation of the cluster with respect to the incident light. This is particularly important in the context of nanoscale chirality and associated chiroptical responses, such as circular dichroism or differential scattering of circularly polarised light in the far-field, or local degree of optical chirality in the near-field. We explore the angular dependence of such quantities for a few archetypal geometries: a dimer of gold nanorods, a helix of gold nanospheres, and a linear chain of silicon particles. The examples serve to illustrate the possible variation of chiroptical responses with the direction of light incidence, but also, consequently, the importance of a robust orientation-averaging procedure when modelling general clusters of particles in random orientation. Our results are obtained with the rigorous superposition T-matrix method, which provides exact analytical formulas for fixed and orientation-averaged properties. This journal is
MPEC 2024-E72 : 2024 ET1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 ET1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
ezBIDS: Guided standardization of neuroimaging data interoperable with major data archives and platforms
Creators: name: Levitas, Daniel
name: Hayashi, Soichi
name: Vinci-Booher, Sophia
name: Heinsfeld, Anibal
name: Bhatia, Dheeraj
name: Lee, Nicholas
name: Galassi, Anthony
name: Niso, Guiomar
name: Pestilli, Franco
Publisher: name: arXiv
Year: 2023
Subjects: subject: Databases (cs.DB)
subject: FOS: Computer and information sciences

description: Data standardization has become one of the leading methods neuroimaging researchers rely on for data sharing and reproducibility. Data standardization promotes a common framework through which researchers can utilize others' data. Yet, as of today, formatting datasets that adhere to community best practices requires technical expertise involving coding and considerable knowledge of file formats and standards. We describe ezBIDS, a tool for converting neuroimaging data and associated metadata to the Brain Imaging Data Structure (BIDS) standard. ezBIDS provides four unique features: (1) No installation or programming requirements. (2) Handling of both imaging and task events data and metadata. (3) Automated inference and guidance for adherence to BIDS. (4) Multiple data management options: download BIDS data to local system, or transfer to OpenNeuro.org or brainlife.io. In sum, ezBIDS requires neither coding proficiency nor knowledge of BIDS and is the first BIDS tool to offer guided standardization, support for task events conversion, and interoperability with OpenNeuro and brainlife.io.
Sugar and artificially sweetened soda consumption linked to hypertension: A systematic review and meta-analysis
Creators: name: Wisit Cheungpasitporn
name: Charat Thongprayoon
name: Edmonds, Peter J.
name: Narat Srivali
name: Patompong Ungprasert
name: Wonngarm Kittanamongkolchai
name: Erickson, Stephen B.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Marine Biology
subject: Biological Sciences
subject: Biotechnology
subject: Medicine

description: Background/objectives: The risk of hypertension (HTN) in patients who regularly drink soda is controversial. The objective of this meta-analysis was to assess the associations between consumption of sugar and artificially sweetened soda and HTN. Methods: A literature search was performed using MEDLINE, EMBASE and Cochrane Database of Systematic Reviews from inception through January 2015. Studies that reported relative risks, odd ratios or hazard ratios comparing the risk of HTN in patients consuming a significant amount of either sugar or artificially sweetened soda versus those who did not consume soda were included. Pooled risk ratios (RR) and 95% confidence interval (CI) were calculated using a random-effect, generic inverse variance method. Results: Eight studies were included in our analysis to assess the association between consumption of sugar-sweetened soda and HTN. The pooled RR of HTN in patients consuming sugar-sweetened soda was 1.12 (95% CI, 1.03–1.23). Four studies were selected to assess the association between consumption of artificially sweetened soda and HTN. The pooled RR of HTN in patients consuming artificially sweetened soda was 1.15 (95% CI, 1.11–1.19). Conclusions: Our study demonstrates statistically significant associations between both sugar and artificially sweetened soda consumption and HTN. This finding may impact clinical management and primary prevention of HTN.
Bis-phenanthridinium–adenine conjugates as fluorescent and CD reporters for fine structural differences in ds-DNA/RNA and ss-RNA structures
Creators: name: Lidija-Marija Tumir
name: Šupljika, Filip
name: Piantanida, Ivo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Plant Biology
subject: 60506 Virology

description: Two structurally similar bis-phenanthridinium–adenine conjugates (equipped with one or two adenines, respectively), exhibiting strong ds-DNA/RNA groove binding, revealed ratiometric fluorescent recognition of alternating AT-DNA with respect to other ds-DNA/RNA and ss-RNA. Further, CD spectra pattern of adenine–bis-phenanthridinium conjugate/polynucleotide complexes strongly depended on polynucleotide secondary structure. Attached adenine was essential for spectrophotometric recognition response, ds-DNA stabilisation and orientation of compounds regarding chiral DNA helix.
КАНПИРАК ДЕВОРИ ТАРИХИ
Creators: name: Ҳожимуродов, Олтинбек
name: Болтаев, Бобир
Publisher: name: Zenodo
Year: 2024

description: Археолог, тарихчилар томонидан «воҳа девори» номи билан аталган ва Буюк Хитой деворига ўхшаб меъморий мудофаа тизими бўлмиш Канпирак девори алоҳида жойлашган бир туркум шаҳар ва қишлоқлардан иборат Бухоро воҳасини ўраб турган. Ушбу иншоотнинг умумий узунлиги 350-400 километр бўлиб, унинг Бухоро воҳасининг бошқа жойларидагига нисбатан яхши сақланган қисми Қизилтепа туманининг маданий ва дашт ҳудудлари бўйлаб ўтган.Шу сабабли ҳам Канпирак деворининг қадим даврлардаги фаолияти, меъморий қурилиш усуллари, ўтмишдаги халқларнинг ҳаёт тарзини ўрганиш бугунги кунда тарихни тиклашда катта аҳамиятга эга.
STUDIO CLINICO_KETO NAFLD 460.2020
Creators: name: IRCCS MultiMedica - Data Management
Publisher: name: Zenodo
Year: 2024

description: TITOLO : Studio per valutare gli effetti della chirurgia metabolico-bariatrica sulla capacità chetogenica in soggetti con obesità e steatosi epatica non alcolica (Keto-NAFLD)

Promotore: MultiMedica con Fondi EFSD

Studio osservazionale prospettico monocentrico

Protocollo e Sinossi Versione 1.0  del 4/11/2020 - Verbale CE 2.2021 e 18.2021
Bis-phenanthridinium–adenine conjugates as fluorescent and CD reporters for fine structural differences in ds-DNA/RNA and ss-RNA structures
Creators: name: Lidija-Marija Tumir
name: Šupljika, Filip
name: Piantanida, Ivo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Plant Biology
subject: 60506 Virology

description: Two structurally similar bis-phenanthridinium–adenine conjugates (equipped with one or two adenines, respectively), exhibiting strong ds-DNA/RNA groove binding, revealed ratiometric fluorescent recognition of alternating AT-DNA with respect to other ds-DNA/RNA and ss-RNA. Further, CD spectra pattern of adenine–bis-phenanthridinium conjugate/polynucleotide complexes strongly depended on polynucleotide secondary structure. Attached adenine was essential for spectrophotometric recognition response, ds-DNA stabilisation and orientation of compounds regarding chiral DNA helix.
Orientation-averaged light scattering by nanoparticle clusters: Far-field and near-field benchmarks of numerical cubature methods
Creators: name: Fazel-Najafabadi, A
name: Auguié, Baptiste
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2022
Subjects: subject: 20299 Atomic, Molecular, Nuclear, Particle and Plasma Physics not elsewhere classified
subject: FOS: Physical sciences
subject: Atmospheric Sciences
subject: FOS: Earth and related environmental sciences
subject: 30699 Physical Chemistry not elsewhere classified
subject: FOS: Chemical sciences

description: No description supplied
Multiple scattering of light in nanoparticle assemblies: User guide for the TERMS program
Creators: name: Schebarchov, D
name: Fazel-Najafabadi, A
name: Le Ru, Eric
name: Auguié, Baptiste
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2022
Subjects: subject: 20299 Atomic, Molecular, Nuclear, Particle and Plasma Physics not elsewhere classified
subject: FOS: Physical sciences
subject: Atmospheric Sciences
subject: FOS: Earth and related environmental sciences
subject: 30699 Physical Chemistry not elsewhere classified
subject: FOS: Chemical sciences

description: We introduce TERMS, an open-source Fortran program to simulate near-field and far-field optical properties of clusters of particles. The program solves rigorously the Maxwell equations via the superposition T-matrix method, where incident and scattered fields are decomposed into series of vector spherical waves. TERMS implements several algorithms to solve the coupled system of multiple scattering equations that describes the electromagnetic interaction between neighbouring scatterers. From this formal solution, the program can compute a number of physically-relevant optical properties, such as far-field cross-sections for extinction, absorption, scattering and their corresponding circular dichroism, as well as local field intensities and degree of optical chirality. By describing the incident and scattered fields in a basis of spherical waves the T-matrix framework lends itself to analytical formulas for orientation-averaged quantities, corresponding to systems of particles in random orientation; TERMS offers such computations for both far-field and near-field quantities of interest. This user guide introduces the program, summarises the relevant theory, and is supplemented by a comprehensive suite of stand-alone examples in the website accompanying the code.
Factors Affecting Couples’ Interactions During Covid-19 in Sri Lanka
Creators: name: Jayawardane, Thesara
name: Wickramasinghe, Vathsala
Publisher: name: International Journal of Economic Behavior  (IJEB)
Year: 2022

description: COVID-19 has made a substantial and irreversible impact on almost all areas of countries around the world and Sri Lanka is no exception. With the restrictions vested upon public as a result of COVID-19 disease, more and more couples claim to have a decrease in their relationship happiness and interaction. Further research in this would ensure to reduce the damage the pandemic would have on couples. Hence, the objectives of this study were to investigate motivational factors affecting couples’ interactions, to investigate stress factors affecting couples’ interactions, to investigate the level of couples’ interactions, to investigate resources available for spouses and to analyse whether resource availability, moderates the relationship between motivational factors/stressors and the level of couples’ interactions. Data was collected from over 300 participants of a convenience sample using an online survey. The couples were adults of 25 years or older, residing in the Western Province of Sri Lanka. Statistical analysis was performed to identify moderator effect of resource availability on the level of couples’ interactions. In conclusion the study emphasised that motivational factors such as family approval and social prestige and stressors such as financial strain and occupational status contribute towards the interaction of couples and they are moderated by resources available to these couples such as cultural beliefs and availability of family support respectively. The study concludes with recommendations of ways to overcome the issues brought upon by COVID-19 on couples’ interaction.
description: International Journal of Economic Behavior (IJEB), Vol. 12 No. 1 (2022): International Journal of Economic Behavior
Biological fitness of Trichoderma atroviride during long-term storage, after production in different culture conditions
Creators: name: Daryaei, Amir
name: E. Eirian Jones
name: Glare, Travis R.
name: Falloon, Richard E.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Physiology
subject: Cell Biology

description: ABSTRACTIdentification of the production and storage factors that affect conidium germination and bioactivity (fitness) will assist the success of biological control agents. Effects of culturing conditions on conidium fitness of Trichoderma atroviride LU132 were examined in different storage conditions over time. Abiotic factors (temperature, nutrients, water activity and pH) during production were studied. Conidia from the culturing regimes which resulted in greatest and least bioactivity against Rhizoctonia solani in dual culture were selected to assess effects of storage conditions on conidium fitness. Fitness of the test conidia was examined after storage at 30°C and at 0% or 50% relative humidity (RH) over 6 months. Fitness declined over time, and the decline was greater for 50% RH than 0% RH, probably through reduced metabolic activity of conidia during long-term storage. Stored conidia were probably affected by dehydration, temperature and other factors such as oxidation, before and during storage, and also by rehydration after storage. The greatest number of conidia and germination percentage resulted from production at 25°C, but greatest bioactivity resulted from those produced at 30°C. No significant effects on bioactivity were detected between the conidium production treatments C : N 5 : 1 and C : N 160 : 1, indicating that C : N ratio in culture medium is not important for conidium survival of T. atroviride.
Virtual screening, docking, and dynamics of potential new inhibitors of dihydrofolate reductase from Yersinia pestis
Creators: name: Bastos, Leonardo Da Costa
name: Souza, Felipe Rodrigues De
name: Guimarães, Ana Paula
name: Sirouspour, Mehdi
name: Guizado, Teobaldo Ricardo Cuya
name: Forgione, Pat
name: Ramalho, Teodorico Castro
name: Tanos Celmar Costa França
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: In the present work, we propose to design drugs that target the enzyme dihydrofolate redutase (DHFR) as a means of a novel drug therapy against plague. Potential inhibitors of DHFR from Yersinia pestis (YpDHFR) were selected by virtual screening and subjected to docking, molecular dynamics (MD) simulations, and Poisson–Boltzmann surface area method, in order to evaluate their interactions in the active sites of YpDHFR and human DHFR (HssDHFR). The results suggested selectivity for three compounds that were further used to propose the structures of six new potential selective inhibitors for YpDHFR.