Metadata record for the article: Risk of primary lung cancer after adjuvant radiotherapy in breast cancer - a large population-based study
Creators: name: Anna-Karin Wennstig
name: Wadsten, Charlotta
name: Garmo, Hans
name: Johansson, Mikael
name: Fredriksson, Irma
name: Blomqvist, Carl
name: Holmberg, Lars
name: Nilsson, Greger
name: Sund, Malin
Publisher: name: figshare
Year: 2021
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: FOS: Biological sciences
subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences
subject: FOS: Other medical sciences
subject: Cancer
subject: 111204 Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
subject: FOS: Clinical medicine
subject: FOS: Clinical medicine
subject: 111299 Oncology and Carcinogenesis not elsewhere classified

description: <b>Summary</b><br> This metadata record provides details of the data supporting the claims of the related article: “Risk of primary lung cancer after adjuvant radiotherapy in breast cancer - a large population-based study”. The related study examined the risk of primary lung cancer in a population-based cohort of 52300 women treated for BC during 1992 to 2012, and 253796 age-matched women without breast cancer. Type of data: estimates of cumulative incidence of lung cancer (calculated by the Kaplan-Meier method) and risk of lung cancer after breast cancer treatment (calculated by Cox proportional hazards regression analyses); registry-based retrospective cohort study Subject of data: <i>Homo sapiens</i> Population characteristics: The Breast Cancer DataBase Sweden (BCBaSe) cohort was used. It comprises all new cases of invasive breast cancer in women from 1992 to 2012 in three Swedish health care regions, and a comparison cohort of five age-matched women without a BC diagnosis for each case of breast cancer. A total of 52300 women with breast cancer were included, and 253796 women without breast cancer. <b>Data access</b> The Breast Cancer DataBase Sweden (BCBaSe) cohort was used in this study. It is a population-based database that comprises all new cases of invasive breast cancer in women from 1992 to 2012 in three Swedish health care regions, and a comparison cohort of five age-matched women without a breast cancer diagnosis for each case of breast cancer. The cohort was linked to a number of national population-based registries. Since BCBaSe contains sensitive health information, it cannot be published in open repositories. Those interested in data from BCBaSe should contact the chairman of the steering committee of the cohort, Malin Sund (malin.sund@umu.se). The estimates of cumulative incidence of lung cancer and risk of lung cancer after breast cancer treatment data are contained in the file ‘LCa_20191204.csv’ which is housed on institutional storage. These data are not publicly available for the following reason: data contain sensitive health information. However, the data can be made available upon request to the corresponding author. <b>Corresponding author(s) for this study</b> Anna-Karin Wennstig PhD, MD, Department of Oncology, Sundsvall hospital, Sweden. anakinwen@gmail.com. <br> <b>Study approval </b> All procedures performed in this study involving human participants were in accordance with the ethical standards of the regional committee of ethics in Stockholm, reference number 2013/1272-31/4 and with the Helsinki declaration and its later amendments or comparable ethical standards. The cohort is based on data from regional and national registries and the need for informed consent was waived.