cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identification and preliminary characterization of a 75-kDa hemin- and hemoglobin-binding outer membrane protein of Actinobacillus pleuropneumoniae serotype 1
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: The reference strains representing serotypes 1 to 12 of Actinobacillus pleuropneumoniae biotype 1 were examined for their ability to utilize porcine hemoglobin (Hb) or porcine hemin (Hm) as iron sources for growth. In a growth promotion assay, all of the reference strains were able to use porcine Hb, and all strains except 2 were able to use porcine Hm. Using a preliminary characterization procedure with Hm- or Hb-agarose, Hm- and Hb-binding outer membrane proteins (OMPs) of approximately 75 kDa were isolated from A. pleuropneumoniae serotype 1 strain 4074 grown under iron-restricted conditions. Matrix-assisted laser desorption ionization/time-of-flight (MALDI-TOF) analysis revealed a number of common tryptic peptides between the Hb-agarose- and Hm-agarose-purified 75 kDa OMPs, strongly suggesting that these peptides originate from the same protein. A database search of these peptide sequences revealed identities with proteins from various Gram-negative bacteria, including iron-regulated OMPs, transporter proteins, as well as TonB-dependent receptors. Taken together, our data suggest that A. pleuropneumoniae synthesizes potential Hm- and Hb-binding proteins that could be implicated in the iron uptake from porcine Hb and Hm.
Methodology and Implementation of a Randomized Controlled Trial (RCT) for Early Post-concussion Rehabilitation: The Active Rehab Study
Creators: name: Marshall, S.W.
name: McCrea, M.
name: McCulloch, K.L.
name: Ranapurwala, S.I.
name: Active Rehab Study Consortium Investigators
name: Mrazik, M.
name: Schneider, K.
name: Register-Mihalik, J.K.
name: Mihalik, J.P.
name: Guskiewicz, K.M.
name: Murphy, I.
name: Naidu, D.
name: Gildner, P.
Publisher: name: Frontiers Media S.A.
Year: 2019

description: Background: Sports-related concussion (SRC) is a complex injury with heterogeneous presentation and management. There are few studies that provide guidance on the most effective and feasible strategies for recovery and return to sports participation. Furthermore, there have been no randomized studies of the feasibility, safety, and efficacy of early rehabilitation strategies across multiple sports and age groups. This international cluster-randomized pragmatic trial evaluates the effectiveness of early multi-dimensional rehabilitation integrated with the current return to sport strategy vs. the current return to sport strategy alone. Methods: The study is a cluster-randomized pragmatic trial enrolling male and female athletes from 28 sites. The sites span three countries, and include multiple sports, levels of play (high school, college, and professional), and levels of contact. The two study arms are Enhanced Graded Exertion (EGE) and Multidimensional Rehabilitation (MDR). The EGE arm follows the current return to sport strategy and the MDR arm integrates early, MDR strategies in the context of the current return to sport strategy. Each arm employs a post-injury protocol that applies to all athletes from that site in the event they sustain a concussion during their study enrollment. Participants are enrolled at pre-season baseline. Assessment timepoints include pre-season baseline, time of injury (concussion), 24–48 h post-injury, asymptomatic, and 1-month post-injury. Symptoms and activity levels are tracked post injury through the return to play process and beyond. Injury and recovery characteristics are obtained for all participants. Primary endpoints include time to medical clearance for full return to sport and time to become asymptomatic. Secondary endpoints include symptom, neurocognitive, mental status, balance, convergence insufficiency, psychological distress, and quality of life trajectories post-injury. Discussion: Outputs from the trial are expected to inform both research and clinical practice in post-concussion rehabilitation across all levels of sport and extend beyond civilian medicine to care for military personnel. Ethics and Dissemination: The study is approved by the data coordinating center Institutional Review Board and registered at clinicaltrials.gov. Dissemination will include peer-reviewed publications, presentation to patients and public groups, as well as dissemination in other healthcare and public venues of interest. Clinical Trial Registration: www.ClinicalTrials.gov, identifier: NCT02988596 Trial Funding: National Football League.
The All-sky Medium Energy Gamma-ray Observatory eXplorer (AMEGO-X) Mission Concept
Creators: name: Caputo, Regina
name: Ajello, Marco
name: Kierans, Carolyn
name: Perkins, Jeremy
name: Racusin, Judith
name: Baldini, Luca
name: Barring, Matthew
name: Bissaldi, Elisabetta
name: Burns, Eric
name: Cannady, Nicolas
name: Charles, Eric
name: da Silva, Rui Curado
name: Fang, Ke
name: Fleischhack, Henrike
name: Fryer, Chris
name: Fukazawa, Yasushi
name: Grove, J. Eric
name: Hartmann, Dieter
name: Howell, Eric
name: Jadhav, Manoj
name: Karwin, Christopher
name: Kocevski, Daniel
name: Kurahashi, Naoko
name: Latronico, Luca
name: Lewis, Tiffany
name: Leys, Richard
name: Lien, Amy
name: Marcotulli, Lea
name: Martinez-Castellanos, Israel
name: Mazziotta, Mario Nicola
name: McEnery, Julie
name: Metcalfe, Jessica
name: Murase, Kohta
name: Negro, Michela
name: Parker, Lucas
name: Phlips, Bernard
name: Prescod-Weinstein, Chanda
name: Razzaque, Soebur
name: Shawhan, Peter
name: Sheng, Yong
name: Shutt, Tom
name: Shy, Daniel
name: Sleator, Clio
name: Steinhebel, Amanda
name: Striebig, Nicolas
name: Suda, Yusuke
name: Tak, Donggeun
name: Tajima, Hiroyasu
name: Valverde, Janeth
name: Venters, Tonia
name: Wadiasingh, Zorawar
name: Woolf, Richard
name: Wulf, Eric
name: Zhang, Haocheng
name: Zoglauer, Andreas
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The All-sky Medium Energy Gamma-ray Observatory eXplorer (AMEGO-X) is designed to identify and characterize gamma rays from extreme explosions and accelerators. The main science themes include: supermassive black holes and their connections to neutrinos and cosmic rays; binary neutron star mergers and the relativistic jets they produce; cosmic ray particle acceleration sources including Galactic supernovae; and continuous monitoring of other astrophysical events and sources over the full sky in this important energy range. AMEGO-X will probe the medium energy gamma-ray band using a single instrument with sensitivity up to an order of magnitude greater than previous telescopes in the energy range 100 keV to 1 GeV that can be only realized in space. During its three-year baseline mission, AMEGO-X will observe nearly the entire sky every two orbits, building up a sensitive all-sky map of gamma-ray sources and emission. AMEGO-X was submitted in the recent 2021 NASA MIDEX Announcement of Opportunity.
description: 23 pages, 16 figures, Published Journal of Astronomical Telescopes, Instruments, and Systems
The Eynard-Orantin recursion and equivariant mirror symmetry for the projective line
Creators: name: Fang, Bohan
name: Liu, Chiu-Chu Melissa
name: Zong, Zhengyu
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: We study the equivariantly perturbed mirror Landau-Ginzburg model of the projective line. We show that the Eynard-Orantin recursion on this model encodes all genus all descendants equivariant Gromov-Witten invariants of the projective line. The non-equivariant limit of this result is the Norbury-Scott conjecture, while by taking large radius limit we recover the Bouchard-Marino conjecture on simple Hurwitz numbers.
description: 34 pages, 5 figures; references added, typos corrected
Hip bone density predicts breast cancer risk independently of Gail score: Results From the Women's Health Initiative
Creators: name: Lewis, Cora E.
name: Cauley, Jane
name: Arendell, Leslie
name: Chlebowski, Rowan
name: Aickin, Mikel
name: Chen, Zhao
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The Gail model has been commonly used to estimate a woman’s breast cancer risk in a certain time period. High bone mineral density (BMD) is also a significant risk factor for breast cancer, but it plays no role in the Gail model. The objective of this study was to investigate whether hip BMD predicts postmenopausal breast cancer risk independently of the Gail score.
Tunable electronic and magnetic phases in layered ruthenates: SrRuO3-SrTiO3 heterostructure upon strain
Creators: name: Kim, Minjae
name: Kang, Chang-Jong
name: Han, Jae-Ho
name: Kim, Kyoo
name: Kim, Bongjae
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Layered ruthenates are a unique class of systems which manifests a variety of electronic and magnetic features emerged from competing energy scales. At the heart of such features lies the multi-orbital physics, especially, the orbital-selective behavior. Here, we propose that the SrRuO3-SrTiO3 heterostructure is a highly tunable platform to obtain the various emergent properties. Employing the density functional theory plus dynamical mean-field theory, we thoroughly investigate the orbital-dependent physics of the system and identify the competing magnetic fluctuations. We show that the epitaxial strain drives the system towards multi-orbital or orbital selective Mott phases from the Hund metal regime. At the same time, the two different types of static magnetism are stabilized, ferromagnetism and checkerboard antiferromagnetism, from the competition with the spin-density wave instability.
description: 5 pages, 3 figures in the main text, Supplemental Material is included
Rubin Observatory: Open Science to the Core
Creators: name: Guy, Leanne
name: AlSayyad, Yusra
name: Dubois-Felsmann, Gregory
name: Economou, Frossie
name: Graham, Melissa
name: O'Mullane, William
name: Slater, Colin
Publisher: name: Zenodo
Year: 2023
Subjects: Rubin Observatory
LSST
Open Science
Cloud

description: Rubin Observatory has made open science a core value of its mission since the beginning of construction and will continue to do so throughout the full 10 years of the Legacy Survey of Space and Time (LSST). We believe that open science is only meaningful if it is supported by well-documented open-source reusable software; our more than 1.5 million lines of code are all publicly accessible on github. But open source is not sufficient; we need to lower barriers to doing science especially for under-resourced and under-represented communities. The Rubin Science Platform (RSP) (LSE-319) democratises access to LSST data products by providing the same level of ease and power to any user anywhere with an internet connection. Rubin Data Previews (RTN-011), early shared-risk previews of the LSST data products and services, are hosted on Google and supported by the Community Science Team’s tutorials and hack sessions. Data Preview 0 has already demonstrated the potential of the RSP for rapidly performing scientific analyses for anyone in the community. The algorithms within our processing software are also discussed with and in some cases contributed to by community members. In addition to open source software and a compute platform, the third leg of our "open science support tripod" is documentation. We consider accessible and complete documentation for code and data products as essential for lowering barriers to participation, and continue to push towards this goal. There are many further challenges to open science such as interoperability. We continue to work with IVOA on standardisation and are committed to our “VO First” approach. We build on the existing standards that enable interoperability; however, we acknowledge that they may not scale to Rubin data volumes and are discussing what to do about that. Our pioneering cloud based solution may also help with interoperability - having all datasets in one place is hard, having them all on one cloud may be possible. We have identified and tackled some of the open science issues and are sure to encounter more on our ten year journey making the Legacy Survey of Space and Time.
The metal-responsive transcription factor-1 protein is elevated in human tumors
Creators: name: Sambucetti, Lidia
name: Sato, Barbara G.
name: Amin, Khalid
name: Shi, Yihui
name: Laderoute, Keith
name: Murphy, Brian J.
name: Samuelsson, Steven J.
name: Haroon, Zishan A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: We previously identified metal-responsive transcription factor-1 (MTF-1) as a positive contributor to mouse fibrosarcoma growth through effects on cell survival, proliferation, tumor angiogenesis and extracellular matrix remodeling. In the present study, we investigated MTF-1 protein expression in human tissues by specific immunostaining of both normal and tumor tissue samples. Immunohistochemical (IHC) staining of a human tissue microarray (TMA), using a unique anti-human MTF-1 antibody, indicated constitutive MTF-1 expression in most normal tissues, with liver and testis displaying comparatively high levels of expression. Nevertheless, MTF-1 protein levels were found to be significantly elevated in diverse human tumor types, including breast, lung and cervical carcinomas. IHC analysis of a separate panel of full-size tissue sections of human breast cancers, including tumor and normal adjacent, surrounding tissue, confirmed and extended the results of the TMA analysis. Taken with our previous findings, this new study suggests a role for MTF-1 in human tumor development, growth or spread. Moreover, the study suggests that MTF-1 could be a novel therapeutic target that offers the opportunity to manipulate metal or redox homeostasis in tumor cells.
Impact of Iowa’s prescription monitoring program on opioid pain reliever prescribing patterns: An interrupted time series study 2003–2014
Creators: name: Hinman, J.
name: Ranapurwala, S.I.
name: Carnahan, R.M.
name: Brown, G.
name: Casteel, C.
Publisher: name: Oxford University Press
Year: 2019

description: Objective. To evaluate the impact of Iowa’s prescription monitoring program (PMP), implemented in 2009, on opioid pain reliever (OPR) prescribing patterns. Methods. We conducted interrupted time series analyses using 2003–2014 health insurance claims from a private health insurer in Iowa. OPR prescriptions for all beneficiaries were included. Another data set included only OPR prescription for new opioid users required to have six months of insurance coverage. We evaluate four OPR prescribing patterns: 1) average daily dosage in morphine milligrams equivalents (MME), 2) MME per prescription, 3) average days’ supply per prescription, and 4) prescription rate per 1,000 insured person-years. We examined confounding and effect measure modification of the relationship between PMP and prescribing patterns by age and sex. Results. During the 12 years of follow-up, 1,512,388 insured Iowans contributed 6,169,634.92 person-years of follow-up. Of these, 505,274 patients filled 2,401,818 OPR prescriptions and 360,688 new OPR users filled as many first OPR prescriptions. The increasing trend of OPR prescription rates from 2003 to 2009 declined post-PMP. Similarly, there was a large decline in MME per day and MME per prescription. The OPR days’ supply kept increasing post-PMP implementation, albeit at a slightly slower rate than pre-PMP implementation. There was no confounding by age and sex; however, we observed heterogeneity by age and sex; patients aged 50 years and females received higher doses and more prescriptions pre-PMP and experienced the greatest declines post-PMP. Conclusions. Our study suggests that Iowa PMP implementation may have resulted in declines in OPR prescribing, and this impact varies by patient age and sex.
Scalable Link Prediction in Dynamic Networks via Non-Negative Matrix Factorization
Creators: name: Zhu, Linhong
name: Guo, Dong
name: Yin, Junming
name: Steeg, Greg Ver
name: Galstyan, Aram
Publisher: name: arXiv
Year: 2014
Subjects: subject: Social and Information Networks (cs.SI)
subject: Artificial Intelligence (cs.AI)
subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences
subject: H.2.8; H.3.4

description: We propose a scalable temporal latent space model for link prediction in dynamic social networks, where the goal is to predict links over time based on a sequence of previous graph snapshots. The model assumes that each user lies in an unobserved latent space and interactions are more likely to form between similar users in the latent space representation. In addition, the model allows each user to gradually move its position in the latent space as the network structure evolves over time. We present a global optimization algorithm to effectively infer the temporal latent space, with a quadratic convergence rate. Two alternative optimization algorithms with local and incremental updates are also proposed, allowing the model to scale to larger networks without compromising prediction accuracy. Empirically, we demonstrate that our model, when evaluated on a number of real-world dynamic networks, significantly outperforms existing approaches for temporal link prediction in terms of both scalability and predictive power.
description: Technical report for paper "Scalable Temporal Latent Space Inference for Link Prediction in Dynamic Social Networks" that appears in IEEE Transactions on Knowledge and Data Engineering 2016
R.P. Ioannis De Lvgo Hispalensis, E Societate Iesv, In Collegio Romano Eivsdem Societatis olim Theologiæ Professoris, nunc S.R.E. Cardinalis, Dispvtationvm De Ivstitia Et Ivre
Creators: name: Lugo, Juan ¬de
Publisher: name: unkn
Year: 2024

description: R.P. Ioannis De Lvgo Hispalensis, E Societate Iesv, In Collegio Romano Eivsdem Societatis olim Theologiæ Professoris, nunc S.R.E. Cardinalis, Dispvtationvm De Ivstitia Et Ivre
description: Tomvs Primvs
On the Entropy of Strings and Branes
Creators: name: Brustein, Ram
name: Zigdon, Yoav
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We show that the entropy of strings that wind around the Euclidean time circle is proportional to the Noether charge associated with translations along the T-dual time direction. We consider an effective target-space field theory which includes a large class of terms in the action with various modes, interactions and $α'$ corrections. The entropy and the Noether charge are shown to depend only on the values of fields at the boundary of space. The classical entropy, which is proportional to the inverse of Newton's constant, is then calculated by evaluating the appropriate boundary term for various geometries with and without a horizon. We verify, in our framework, that for higher-curvature pure gravity theories, the Wald entropy of static neutral black hole solutions is equal to the entropy derived from the Gibbons-Hawking boundary term. We then proceed to discuss horizonless geometries which contain, due to the back-reaction of the strings and branes, a second boundary in addition to the asymptotic boundary. Near this ``punctured'' boundary, the time-time component of the metric and the derivatives of its logarithm approach zero. Assuming that there are such non-singular solutions, we identify the entropy of the strings and branes in this geometry with the entropy of the solution to all orders in $α'$. If the asymptotic region of an $α'$-corrected neutral black hole is connected through the bulk to a puncture, then the black hole entropy is equal to the entropy of the strings and branes. Later, we discuss configurations similar to the charged black p-brane solutions of Horowitz and Strominger, with the second boundary, and show that, to leading order in the $α'$ expansion, the classical entropy of the strings and branes is equal exactly to the Bekenstein-Hawking entropy. This result is extended to a configuration that asymptotes to AdS.
description: 47 pages, 1 figure, 1 table, 1 appendix, published version
A case–control study of tobacco use and other non-occupational risk factors for lymphoma subtypes defined by t(14; 18) translocations and bcl-2 expression
Creators: name: Conway, Kathleen
name: Blair, Aaron
name: Lynch, Charles F.
name: Olshan, Andrew F.
name: Chang, Cindy M.
name: Huang, Wen-Yi
name: Rothman, Nathaniel
name: Baric, Ralph S.
name: Cerhan, James R.
name: Cantor, Kenneth P.
name: Schroeder, Jane C.
name: Dunphy, Cherie H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: We re-evaluated reported associations between tobacco use and other factors and non-Hodgkin lymphoma (NHL) t(14;18)-subtypes based on fluorescence in situ hybridization (FISH) assays believed to be more sensitive than polymerase chain reaction (PCR), previously used for detecting t(14;18).
Solving the Shortest Vector Problem in $2^n$ Time via Discrete Gaussian Sampling
Creators: name: Aggarwal, Divesh
name: Dadush, Daniel
name: Regev, Oded
name: Stephens-Davidowitz, Noah
Publisher: name: arXiv
Year: 2014
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences

description: We give a randomized $2^{n+o(n)}$-time and space algorithm for solving the Shortest Vector Problem (SVP) on n-dimensional Euclidean lattices. This improves on the previous fastest algorithm: the deterministic $\widetilde{O}(4^n)$-time and $\widetilde{O}(2^n)$-space algorithm of Micciancio and Voulgaris (STOC 2010, SIAM J. Comp. 2013). In fact, we give a conceptually simple algorithm that solves the (in our opinion, even more interesting) problem of discrete Gaussian sampling (DGS). More specifically, we show how to sample $2^{n/2}$ vectors from the discrete Gaussian distribution at any parameter in $2^{n+o(n)}$ time and space. (Prior work only solved DGS for very large parameters.) Our SVP result then follows from a natural reduction from SVP to DGS. We also show that our DGS algorithm implies a $2^{n + o(n)}$-time algorithm that approximates the Closest Vector Problem to within a factor of $1.97$. In addition, we give a more refined algorithm for DGS above the so-called smoothing parameter of the lattice, which can generate $2^{n/2}$ discrete Gaussian samples in just $2^{n/2+o(n)}$ time and space. Among other things, this implies a $2^{n/2+o(n)}$-time and space algorithm for $1.93$-approximate decision SVP.
Axonopsis (Axonopsis) indica Cook 1967
Creators: name: Pešić, Vladimir
name: Chatterjee, Tapas
name: Bordoloi, Sabitry
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Axonopsidae
Axonopsis
Axonopsis indica

description: Axonopsis (Axonopsis) indica Cook, 1967
Records from the study area: Maharashtra—Cook (1967); Prasad (1974).
Habitat: Streams.
Distribution: India.
description: Published as part of Pešić, Vladimir, Chatterjee, Tapas & Bordoloi, Sabitry, 2010, A checklist of the water mites (Acari: Hydrachnidia) of India, with new records and description of one new species, pp. 1-54 in Zootaxa 2617 (1) on page 18, DOI: 10.11646/zootaxa.2617.1.1, http://zenodo.org/record/197964
A Measurement of the Cosmic Microwave Background Gravitational Lensing Potential from 100 Square Degrees of SPTpol Data
Creators: name: Story, K. T.
name: Hanson, D.
name: Ade, P. A. R.
name: Aird, K. A.
name: Austermann, J. E.
name: Beall, J. A.
name: Bender, A. N.
name: Benson, B. A.
name: Bleem, L. E.
name: Carlstrom, J. E.
name: Chang, C. L.
name: Chiang, H. C.
name: Cho, H-M.
name: Citron, R.
name: Crawford, T. M.
name: Crites, A. T.
name: de Haan, T.
name: Dobbs, M. A.
name: Everett, W.
name: Gallicchio, J.
name: Gao, J.
name: George, E. M.
name: Gilbert, A.
name: Halverson, N. W.
name: Harrington, N.
name: Henning, J. W.
name: Hilton, G. C.
name: Holder, G. P.
name: Holzapfel, W. L.
name: Hoover, S.
name: Hou, Z.
name: Hrubes, J. D.
name: Huang, N.
name: Hubmayr, J.
name: Irwin, K. D.
name: Keisler, R.
name: Knox, L.
name: Lee, A. T.
name: Leitch, E. M.
name: Li, D.
name: Liang, C.
name: Luong-Van, D.
name: McMahon, J. J.
name: Mehl, J.
name: Meyer, S. S.
name: Mocanu, L.
name: Montroy, T. E.
name: Natoli, T.
name: Nibarger, J. P.
name: Novosad, V.
name: Padin, S.
name: Pryke, C.
name: Reichardt, C. L.
name: Ruhl, J. E.
name: Saliwanchik, B. R.
name: Sayre, J. T.
name: Schaffer, K. K.
name: Smecher, G.
name: Stark, A. A.
name: Tucker, C.
name: Vanderlinde, K.
name: Vieira, J. D.
name: Wang, G.
name: Whitehorn, N.
name: Yefremenko, V.
name: Zahn, O.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a measurement of the cosmic microwave background (CMB) gravitational lensing potential using data from the first two seasons of observations with SPTpol, the polarization-sensitive receiver currently installed on the South Pole Telescope (SPT). The observations used in this work cover 100 deg$^2$ of sky with arcminute resolution at 150 GHz. Using a quadratic estimator, we make maps of the CMB lensing potential from combinations of CMB temperature and polarization maps. We combine these lensing potential maps to form a minimum-variance (MV) map. The lensing potential is measured with a signal-to-noise ratio of greater than one for angular multipoles between $100< L <250$. This is the highest signal-to-noise mass map made from the CMB to date and will be powerful in cross-correlation with other tracers of large-scale structure. We calculate the power spectrum of the lensing potential for each estimator, and we report the value of the MV power spectrum between $100< L <2000$ as our primary result. We constrain the ratio of the spectrum to a fiducial $Λ$CDM model to be $A_{\rm MV}=0.92 \pm 0.14 {\rm\, (Stat.)} \pm 0.08 {\rm\, (Sys.)}$. Restricting ourselves to polarized data only, we find $A_{\rm POL}=0.92 \pm 0.24 {\rm\, (Stat.)} \pm 0.11 {\rm\, (Sys.)}$. This measurement rejects the hypothesis of no lensing at $5.9 σ$ using polarization data alone, and at $14 σ$ using both temperature and polarization data.
description: 16 pages, 8 figures
Methodologic limitations of prescription opioid safety research and recommendations for improving the evidence base
Creators: name: Marshall, S.W.
name: Naumann, R.B.
name: Ranapurwala, S.I.
name: Austin, A.E.
name: Dasgupta, N.
Publisher: name: John Wiley and Sons Ltd
Year: 2019

description: Purpose: The ongoing opioid epidemic has claimed more than a quarter million Americans' lives over the past 15 years. The epidemic began with an escalation of prescription opioid deaths and has now evolved to include secondary waves of illicit heroin and fentanyl deaths, while the deaths due to prescription opioid overdoses are still increasing. In response, the Centers for Disease Control and Prevention (CDC) moved to limit opioid prescribing with the release of opioid prescribing guidelines for chronic noncancer pain in March 2016. The guidelines represent a logical and timely federal response to this growing crisis. However, CDC acknowledged that the evidence base linking opioid prescribing to opioid use disorders and overdose was grades 3 and 4. Methods: Motivated by the need to strengthen the evidence base, this review details limitations of the opioid safety studies cited in the CDC guidelines with a focus on methodological limitations related to internal and external validity. Results: Internal validity concerns were related to poor confounding control, variable misclassification, selection bias, competing risks, and potential competing interventions. External validity concerns arose from the use of limited source populations, historical data (in a fast-changing epidemic), and issues with handling of cancer and acute pain patients' data. We provide a nonexhaustive list of 7 recommendations to address these limitations in future opioid safety studies. Conclusion: Strengthening the opioid safety evidence base will aid any future revisions of the CDC guidelines and enhance their prevention impact.
Statin use and risk of hepatocellular carcinoma in a U.S. population
Creators: name: Engel, Lawrence S.
name: Divine, George W.
name: Alford, Sharon Hensley
name: McGlynn, Katherine A.
name: VanSlooten, Ashley
name: Wells, Karen
name: Yood, Marianne Ulcickas
name: Sahasrabuddhe, Vikrant V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are medications widely prescribed to reduce cholesterol levels. Observational studies in high-risk populations, mostly in Asia, have suggested that statins are associated with a reduced risk of hepatocellular carcinoma (HCC). The current study sought to evaluate the association of statin use and HCC in a U.S.-based, low-risk, general population.
Periodic Coupled-Cluster Green's Function for Photoemission Spectra of Realistic Solids
Creators: name: Laughon, Katelyn
name: Yu, Jason M.
name: Zhu, Tianyu
Publisher: name: arXiv
Year: 2022
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present an efficient implementation of coupled-cluster Green's function (CCGF) method for simulating photoemission spectra of periodic systems. We formulate the periodic CCGF approach with Brillouin zone sampling in Gaussian basis at the coupled-cluster singles and doubles (CCSD) level. To enable CCGF calculations of realistic solids, we propose an active-space self-energy correction scheme by combining CCGF with cheaper many-body perturbation theory (GW) and implement the model order reduction (MOR) frequency interpolation technique. We find that the active-space self-energy correction and MOR techniques significantly reduce the computational cost of CCGF while maintaining the high accuracy. We apply the developed CCGF approaches to compute spectral properties and band structure of silicon (Si) and zinc oxide (ZnO) crystals using triple-$ζ$ Gaussian basis and medium-size k-point sampling, and find good agreement with experimental measurements.
description: 7 pages, 4 figures, 1 table
Academic Evaluation on Possible Risk Factors Affecting Post-Tonsillectomy Bleeding
Creators: name: Akçam, Ersin
Publisher: name: Zenodo
Year: 2023

description: In the present era, the occurrence of post-tonsillectomy hemorrhage (PHS) has become a significant and potentially perilous complication. In order to mitigate the potential risk factors for hemorrhaging, it can be advantageous to possess knowledge regarding the numerous factors that contribute to bleeding. The aim of this study was to determine the prevalence of post-tonsillectomy hemorrhage in a clinical setting, as well as to identify the risk factors associated with the occurrence of this complication. The present study examines the medical records of patients who underwent tonsillectomy at our clinic within the timeframe spanning from January 2013 to December 2018. The study examined numerous factors pertaining to the patients, encompassing their age, gender, surgical technique, preoperative hemoglobin, platelet, and INR levels, severity of bleeding, and the existence of infection in the tonsillar bed. The study included a cohort of 776 participants. Among the 776 patients included in the sample, a considerable proportion of 624 individuals (80.4%) were identified as children, whereas the remaining 152 patients (19.6%) were classified as adults. Notwithstanding this dispersion, the mean age of the entire cohort was calculated to be 11.7 ±12 years. The research findings indicate that there is a higher incidence of Tuberous Sclerosis Complex (TSC) within the adult demographic, specifically at a rate of 7.8%. Likewise, it was observed that children also demonstrated a comparatively higher occurrence of TSC, with a prevalence rate of 0.14%. No statistically significant correlation was found between preoperative levels of hemoglobin, platelet (PLT), INR, and the various stages of tonsil cases (stage 0, 1, 2, 3, 4). The consideration of post-tonsillectomy bleeding in older individuals holds significant importance.
Chronic administration of ethanol leads to an increased incidence of hepatocellular adenoma by promoting H-ras-mutated cells
Creators: name: Pogribny, Igor P.
name: Rusyn, Ivan
name: Jeannot, Emmanuelle
name: Beland, Frederick A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: This study used tissue samples from male B6C3F1 mice treated with ethanol in drinking water (0, 2.5, or 5%) for 4 or 104 weeks. We tested whether chronic alcohol drinking promotes oxidative stress in the liver and characterized the mutation profile of spontaneous and ethanol-induced tumors. We show that ethanol does not cause detectable oxidative stress in the liver at any time point and acts by promoting H-ras mutated cells.
Constructing A Flexible Likelihood Function For Spectroscopic Inference
Creators: name: Czekala, Ian
name: Andrews, Sean M.
name: Mandel, Kaisey S.
name: Hogg, David W.
name: Green, Gregory M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We present a modular, extensible likelihood framework for spectroscopic inference based on synthetic model spectra. The subtraction of an imperfect model from a continuously sampled spectrum introduces covariance between adjacent datapoints (pixels) into the residual spectrum. For the high signal-to-noise data with large spectral range that is commonly employed in stellar astrophysics, that covariant structure can lead to dramatically underestimated parameter uncertainties (and, in some cases, biases). We construct a likelihood function that accounts for the structure of the covariance matrix, utilizing the machinery of Gaussian process kernels. This framework specifically address the common problem of mismatches in model spectral line strengths (with respect to data) due to intrinsic model imperfections (e.g., in the atomic/molecular databases or opacity prescriptions) by developing a novel local covariance kernel formalism that identifies and self-consistently downweights pathological spectral line "outliers." By fitting many spectra in a hierarchical manner, these local kernels provide a mechanism to learn about and build data-driven corrections to synthetic spectral libraries. An open-source software implementation of this approach is available at http://iancze.github.io/Starfish, including a sophisticated probabilistic scheme for spectral interpolation when using model libraries that are sparsely sampled in the stellar parameters. We demonstrate some salient features of the framework by fitting the high resolution $V$-band spectrum of WASP-14, an F5 dwarf with a transiting exoplanet, and the moderate resolution $K$-band spectrum of Gliese 51, an M5 field dwarf.
description: Accepted to ApJ. Incorporated referees' comments. New figures 1, 8, 10, 12, and 14. Supplemental website: http://iancze.github.io/Starfish/
Evaluating the Q-score of Quantum Annealers
Creators: name: van der Schoot, Ward
name: Leermakers, Daan
name: Wezeman, Robert
name: Neumann, Niels
name: Phillipson, Frank
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We report the Atos Q-score for D-Wave's quantum devices, classical algorithms and hybrid quantum-classical solver. Computing the Q-score entails solving the Max-Cut problem for increasingly large graphs. This work presents the first computation of the Q-score on a quantum device and shows how these quantum devices compare to classical devices at solving optimisation problems. We use D-Wave's standard methods out of the box with a time limit of 60 seconds. The Q-score for D-Wave's 2000Q and Advantage devices are 70 and 140, respectively. The Q-score for two of D-Wave's classical algorithms, based on tabu search and simulated annealing respectively, are 2,300 and 5,800. Finally, we report the out-of-the-box hybrid approach to have a Q-score of 12,500.
description: 8 pages, 6 figures. Submitted to IEEE QSW 2022
Predictors of Depression Among Older African American Cancer Patients
Creators: name: Hamilton, Jill B.
name: Moore, Charles E.
name: Crandell, Jamie L.
name: Agarwal, Mansi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Depression is becoming an increasing concern in cancer patients because of its impact on quality of life. Although risk factors of having depression have been examined in the literature, there has been no research examining these factors in older African American cancer patients.
Association of State Firearm Legislation With Female Intimate Partner Homicide
Creators: name: Marshall, S.W.
name: Sivaraman, J.J.
name: Ranapurwala, S.I.
name: Moracco, K.E.
Publisher: name: Elsevier Inc.
Year: 2019

description: Introduction: The aim of this study was to assess the association between state firearm legislation and female intimate partner homicide. Methods: In 2017, the authors conducted a secondary data analysis of 16 states from 2010 to 2014, using data from the National Violent Death Reporting System, the State Firearm Law Database, and additional public sources. Poisson regression analyses quantified the association between the number of state restrictive firearm legislative provisions and the female population-based intimate partner homicide rate. For etiologic reasons, intimate partner homicide was disaggregated into homicide–suicide (intimate partner homicide followed by perpetrator suicide) and homicide-only intimate partner homicide (intimate partner homicide in the absence of perpetrator suicide). Results: There were 1,693 female intimate partner homicide deaths in the 16 states during 2010–2014; 67% were homicide-only intimate partner homicide. The number of state-level legislative provisions related to firearm restrictions ranged from four (Alaska) to 95 (Massachusetts). The intimate partner homicide rate in states with zero to 39 provisions was 1.16 per 100,000 person years (95% CI=1.10, 1.22) and in states with >40 provisions was 0.68 per 100,000 person years (95% CI=0.61, 0.72). The incidence of female intimate partner homicide was 56% lower in states with ≥40 legislative provisions (adjusted incidence rate ratio=0.44, 95% CI=0.28, 0.68), relative to states with zero to 39 provisions. This protective association was stronger for homicide-only intimate partner homicide than homicide–suicide intimate partner homicide. Conclusions: More state-level restrictive firearm legislation is associated with a lower rate of female intimate partner homicides.
Tensor Network Renormalization
Creators: name: Evenbly, Glen
name: Vidal, Guifre
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We introduce a coarse-graining transformation for tensor networks that can be applied to study both the partition function of a classical statistical system and the Euclidean path integral of a quantum many-body system. The scheme is based upon the insertion of optimized unitary and isometric tensors (disentanglers and isometries) into the tensor network and has, as its key feature, the ability to remove short-range entanglement/correlations at each coarse-graining step. Removal of short-range entanglement results in scale invariance being explicitly recovered at criticality. In this way we obtain a proper renormalization group flow (in the space of tensors), one that in particular (i) is computationally sustainable, even for critical systems, and (ii) has the correct structure of fixed points, both at criticality and away from it. We demonstrate the proposed approach in the context of the 2D classical Ising model.
description: Revised version, with improved numeric results and an additional appendix. Main text: 5 pages, 4 figures, Appendices: 9 pages, 12 figures
supplementary table 2 highly cited papers .pdf
Creators: name: Bauman, Adrian
Publisher: name: figshare
Year: 2022
Subjects: subject: 111706 Epidemiology
subject: FOS: Health sciences

description: supplmentary table 2 for a published paper
 PAPER: Physical activity research in the first 15 years of the “45 and Up” cohort study: a narrative review and citation analysis published in Public Health Research and Practice, December 2022
Thermal blurring of a coherent Fermi gas
Creators: name: Kurkjian, Hadrien
name: Castin, Yvan
name: Sinatra, Alice
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: It is generally assumed that a condensate of paired fermions at equilibrium is characterized by a macroscopic wavefunction with a well-defined, immutable phase. In reality, all systems have a finite size and are prepared at non-zero temperature; the condensate has then a finite coherence time, even when the system is isolated in its evolution and the particle number $N$ is fixed. The loss of phase memory is due to interactions of the condensate with the excited modes that constitute a dephasing environment. This fundamental effect, crucial for applications using the condensate of pairs' macroscopic coherence, was scarcely studied. We link the coherence time to the condensate phase dynamics, and we show with a microscopic theory that the time derivative of the condensate phase operator $\hatθ\_0$ is proportional to a chemical potential operator that we construct including both the pair-breaking and pair-motion excitation branches. In a single realization of energy $E$, $\hatθ\_0$ evolves at long times as $-2μ\_{\rm mc}(E)t/\hbar$ where $μ\_{\rm mc}(E)$ is the microcanonical chemical potential; energy fluctuations from one realization to the other then lead to a ballistic spreading of the phase and to a Gaussian decay of the temporal coherence function with a characteristic time $\propto N^{1/2}$. In the absence of energy fluctuations, the coherence time scales as $N$ due to the diffusive motion of $\hatθ\_0$. We propose a method to measure the coherence time with ultracold atoms, which we predict to be tens of milliseconds for the canonical ensemble unitary Fermi gas.
description: published version in English (13 pages) and in French (14 pages)
Capacity of a Simple Intercellular Signal Transduction Channel
Creators: name: Thomas, Peter J.
name: Eckford, Andrew W.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Molecular Networks (q-bio.MN)
subject: FOS: Biological sciences

description: We model biochemical signal transduction, based on a ligand-receptor binding mechanism, as a discrete-time finite-state Markov channel, which we call the BIND channel. We show how to obtain the capacity of this channel, for the case of binary output, binary channel state, and arbitrary finite input alphabets. We show that the capacity-achieving input distribution is IID. Further, we show that feedback does not increase the capacity of this channel. We show how the capacity of the discrete-time channel approaches the capacity of Kabanov's Poisson channel, in the limit of short time steps and rapid ligand release.
description: Accepted for publication in IEEE Transactions on Information Theory
Agroeca C. L. Koch
Creators: name: Bosmans, Robert
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Liocranidae
Agroeca

description: Genus Agroeca C. L. Koch The genus Agroeca currently includes 25 species and has a Holarctic distribution (PLATNICK 2010). In Greece, only Agroeca cuprea Menge, 1873 has been previously reported (BOSMANS & CHATZAKI2005). A new species is described below.
description: Published as part of Robert Bosmans, 2011, On some new or rare spider species from Lesbos, Greece (Araneae: Agelenidae, Amaurobiidae, Corinnidae, Gnaphosidae, Liocranidae), pp. 15-22 in Arachnologische Mitteilungen 40 (1) on page 19, DOI: 10.5431/aramit4003, http://zenodo.org/record/814865
description: {"references": ["PLATNICK N. (2010): The world spider catalog, version 10.5 American Museum ofNatural History. - Internet: http: // research. amnh. org / entomology / spiders / catalog", "BOSMANS R. & M. CHATZAKI (2005): A catalogue of the spiders of Greece. A critical review of all spiders species cited from Greece with their localities. - Nieuwsbrief van de Belgische arachnologische Vereniging 20 (2, suppl.): 1 - 124"]}
Millimeter Gap Contrast as a Probe for Turbulence Level in Protoplanetary Disks
Creators: name: Liu, Yao
name: Bertrang, Gesa H. -M.
name: Flock, Mario
name: Rosotti, Giovanni P.
name: van Dishoeck, Ewine F.
name: Boehler, Yann
name: Facchini, Stefano
name: Cui, Can
name: Wolf, Sebastian
name: Fang, Min
Publisher: name: arXiv
Year: 2022
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Turbulent motions are believed to regulate angular momentum transport and influence dust evolution in protoplanetary disks. Measuring the strength of turbulence is challenging through gas line observations because of the requirement for high spatial and spectral resolution data, and an exquisite determination of the temperature. In this work, taking the well-known HD 163296 disk as an example, we investigated the contrast of gaps identified in high angular resolution continuum images as a probe for the level of turbulence. With self-consistent radiative transfer models, we simultaneously analyzed the radial brightness profiles along the disk major and minor axes, and the azimuthal brightness profiles of the B67 and B100 rings. By fitting all the gap contrasts measured from these profiles, we constrained the gas-to-dust scale height ratio $Λ$ to be $3.0_{-0.8}^{+0.3}$, $1.2_{-0.1}^{+0.1}$ and ${\ge}\,6.5$ for the D48, B67 and B100 regions, respectively. The varying gas-to-dust scale height ratios indicate that the degree of dust settling changes with radius. The inferred values for $Λ$ translate into a turbulence level of $α_{\rm turb}\,{<}\,3\times10^{-3}$ in the D48 and B100 regions, which is consistent with previous upper limits set by gas line observations. However, turbulent motions in the B67 ring are strong with $α_{\rm turb}\,{\sim}1.2\,{\times}\,10^{-2}$. Due to the degeneracy between $Λ$ and the depth of dust surface density drops, the turbulence strength in the D86 gap region is not constrained.
description: 13 pages, 7 figures, accepted for publication in Science China Physics, Mechanics & Astronomy