cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Grinding parameters prediction under different cooling environments using machine learning techniques
Creators: name: Prashanth, Gorantala Sai
name: Sekar, Prithivirajan
name: Bontha, Srikanth
name: Balan, A.S.S.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Selection of optimum process parameters is vital for performing a sound grinding operation on Inconel 751 alloy. This paper co-relates the relationship between the most influential input parameters like cutting velocity, depth of cut, feed rate, and environmental conditions to the output parameters, namely, tangential grinding forces, normal grinding forces, temperature, and surface roughness. Three types of machine-learning (ML) algorithms such as support vector machine (SVM), Gaussian process regression (GPR), and boosted tree ensemble techniques are employed to develop a ML model for predicting the output variables during grinding operation of Inconel 751. In order to develop a better ML model, K-fold technique is employed on a total of 81 datasets which are extracted from experimental studies. ML models developed from different algorithms are compared based on performance metrics like R2 score and root-mean-square error (RMSE). GPR algorithm exhibits best results with relatively better R2 score and RMSE value in predicting grinding forces and temperature at wheel work interface. From analyzing the ML models, it is found that cooling environments determined the output grinding parameters to a greater extent when compared with the input grinding parameters.
title: Performance comparison of Ingenuity TF PET/MRI and Gemini TF PET/CTscanners
Creators: name: Oprea-Lager, Daniela
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Molecular imaging
subject: MR physics
subject: Oncology
subject: PET-MR
subject: PET-CT
subject: Outcomes analysis
subject: Comparative studies
subject: Outcomes

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: PET/MRI is the obvious next step towards integration of multiparametric imaging data into clinical medicine and medical research [1-4]. It provides structural, functional and biochemical information at the same time. To date, a few years after the...
AI-guided optimization of manufacturing protocols for AHSS coils
Creators: name: Jha, Rajesh
name: Patra, Pradip K.
name: Srivastava, Ashok K.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology
subject: Computational Biology

description: Manufacturing protocols or processing parameters in a coiling mill affect multiple desired properties of advanced high-strength steel (AHSS) coils. These properties include yield strength (YS), ultimate tensile strength (UTS), elongation percent, hardness, etc. In this work, attempts were made to maximize YS, UTS, and elongation percent for AHSS coils while determining the operating parameters that can be helpful in achieving those properties. Additionally, operating parameters were also determined for a few specific grades of AHSS steel with respect to desired properties of interest. Actual plant data from a coiling mill was analyzed through a set of statistical and artificial intelligence (AI) based algorithms. Predictive models were developed through k-Nearest Neighbor (k-NN) algorithm. Optimization of multiple properties was performed through a non-dominated sorting genetic algorithm (NSGA2). The concept of parallel coordinate chart (PCC) was used for visualization as well as identifying operational parameter that can be helpful in achieving a desired property. The research methods and findings presented in this article are of industrial significance and can be applied to other manufacturing processes.
El Pueblo, Inc.: Strengthening El Pueblo's Sexual and Reproductive Health Program for Latino/a Youth in North Carolina
Creators: name: Mann, Lilli
name: Fitzgerald, Anne
name: Garrett, Jenna
name: Muqueeth, Sadiya
name: Martens, Christa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Background: Latinos/as in the United States face significant sexual and reproductive health (SRH) disparities; the rapidly growing Latino/a population in Wake County, North Carolina is no exception. El Pueblo, Inc. is a nonprofit agency that aims to bridge the gap between the needs of the Latino/a community and available resources in Wake County. One way in which El Pueblo achieves this is through a youth SRH education program called Nuestros Derechos sin Fronteras (DsF), or Our Rights Have No Borders. During the 2011-2012 academic year, a Capstone team from the Health Behavior Department at the UNC-Chapel Hill Gillings School of Global Public Health partnered with El Pueblo to complete a project aimed at strengthening the DsF program. Methods: The Capstone team conducted informal community engagement and formal assessment activities, including 15 in-depth interviews with El Pueblo staff and four focus groups with youth who have participated in DsF, and their parents. The Capstone team conducted a qualitative analysis of interview and focus group summary reports, the results of which were used to develop four major deliverables aimed at strengthening the DsF program. The Capstone team additionally conducted a literature review and resource scan to supplement engagement and assessment findings. Results: The results from community engagement emphasized the key factors of upmost importance to the Latino/a community and El Pueblo; these included cultural values, structural discrimination against immigrants, and bi-cultural and generational challenges for Latino/a youth. The results from assessment activities provided direct feedback regarding the DsF program; findings included an emphasis on funding and evaluation challenges, the importance of holistic SRH education for Latino/a youth, an increased need for synergy across El Pueblo programs, and an emphasis on male involvement. Sustainability findings place an emphasis on institutionalization of DsF within El Pueblo and capacity building for program continuation. These findings were all addressed through the four deliverables produced by the Capstone team. Discussion: The Capstone project's findings and subsequent deliverables add value to El Pueblo's SRH programming and provide significant benefits to Latino/a youth in North Carolina. These deliverables will lead to improved knowledge and skills among youth participants, and enhanced program sustainability, which will ultimately lead to improved SRH outcomes for Latino/a youth in North Carolina. Specific limitations and challenges are acknowledged, and are accompanied by recommendations regarding the use of project deliverables and next steps in order to ensure that maximum benefits are achieved.
Additional file 1 of Pilot study on the feasibility of shape memory alloy implantation for Vancouver type B1 periprosthetic femoral fractures in a canine model: a step toward advancing treatment modalities
Creators: name: Kim, Hyunsoo
name: Kang, Kyu-Won
name: Chekalkin, Timofey
name: Park, Jang-Woo
name: Chung, Hye-Kyung
name: Kang, Byung-Jae
name: Choi, Sung-Woo
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Hematology

description: Supplementary Material 1
title: Mid-term result of preventive embolization of renal angiomyolipomas: evaluation of predictive factors of volume decrease.
Creators: name: Grenier, Nicolas
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Kidney
subject: Interventional vascular
subject: Oncology
subject: Catheter arteriography
subject: CT
subject: Embolisation
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To evaluate the efficacy of selective arterial embolization (SAE) of angiomyolipoma based on the percentage of volume reduction after embolization, and to identify predictive factors of volume...
Proposal for ultrafast switching of ferroelectrics using mid-infrared pulses
Creators: name: Subedi, Alaska
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: I propose a method for ultrafast switching of ferroelectric polarization using mid-infrared pulses. This involves selectively exciting the highest frequency $A_1$ phonon mode of a ferroelectric material with an intense mid-infrared pulse. Large amplitude oscillations of this mode provides a unidirectional force to the lattice such that it displaces along the lowest frequency $A_1$ phonon mode coordinate because of a nonlinear coupling of the type $g Q_{\textrm{P}} Q_{\textrm{IR}}^2$ between the two modes. First principles calculations show that this coupling is large in transition-metal oxide ferroelectrics, and the sign of the coupling is such that the lattice displaces in the switching direction. Furthermore, I find that the lowest frequency $A_1$ mode has a large $Q_{\textrm{P}}^3$ order anharmonicity, which causes a discontinuous switch of electric polarization as the pump amplitude is continuously increased.
Additional file 3 of Pilot study on the feasibility of shape memory alloy implantation for Vancouver type B1 periprosthetic femoral fractures in a canine model: a step toward advancing treatment modalities
Creators: name: Kim, Hyunsoo
name: Kang, Kyu-Won
name: Chekalkin, Timofey
name: Park, Jang-Woo
name: Chung, Hye-Kyung
name: Kang, Byung-Jae
name: Choi, Sung-Woo
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Hematology

description: Supplementary Material 3
A Kinematic Condition on Intrinsic Charm
Creators: name: Blümlein, Johannes
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We derive a kinematic condition on the resolution of intrinsic charm and discuss phenomenological consequences.
description: 6 pages, 3 Figures, final version appearing in the Journal
title: Angiosarcoma: Review of CT and MR Imaging features
Creators: name: Kumasaka, Soma
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Oncology
subject: CT
subject: MR
subject: PET-CT
subject: Diagnostic procedure
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review 1) the clinical features of angiosarcoma, 2) its imaging findings (on magnetic resonance imaging (MRI), computed Tomography (CT), and fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET)), and 3) its differential...
Robust self-trapping of vortex beams in a saturable optical medium
Creators: name: Reyna, Albert S.
name: Boudebs, Georges
name: Malomed, Boris A.
name: de Araújo, Cid B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We report the first observation of robust self-trapping of vortex beams propagating in a uniform condensed medium featuring local saturable self-focusing nonlinearity. Optical vortices with topological charge m=1, that remain self-trapped over ~ 5 Rayleigh lengths, are excited in carbon disulfide using a helical light beam at 532 nm and intensities from 8 to 10 GW/cm^2. At larger intensities, the vortex beams lose their stability, spontaneously breaking into two fragments. Numerical simulations based on the nonlinear Schrödinger equation including the three-photon absorption and nonpolynomial saturation of the refractive nonlinearity demonstrate close agreement with the experimental findings.
description: 27 pages, 7 figures,to be published in Phys. Rev. A (2016)
title: Evaluation of anxiety level in patients wating to undergo to diagnostic radiological exams
Creators: name: Muscarneri, Filippa
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Oncology
subject: Breast
subject: MR
subject: CT
subject: Mammography
subject: Diagnostic procedure
subject: Psycho-oncology
subject: Outcomes

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To evaluate the anxiety level of patients waiting to undergo diagnostic radiological exams, for screening or follow-up, especially in oncological patients and ones who had to undergo breast...
title: Spectral CT and malignant breast lesions
Creators: name: Ardies, Lenz
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Cancer
subject: Diagnostic procedure
subject: CT
subject: Oncology
subject: Breast

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To explore the possible role of single source dual-energy or spectral CT in the detection and diagnosis of breast cancer, the evaluation of axillary lymph node involvement and to evaluate tumor response to...
Sieving hydrogen isotopes through two dimensional crystals
Creators: name: Lozada-Hidalgo, M.
name: Hu, S.
name: Marshall, O.
name: Mishchenko, A.
name: Grigorenko, A. N.
name: Dryfe, R. A. W.
name: Radha, B.
name: Grigorieva, I. V.
name: Geim, A. K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: One-atom-thick crystals are impermeable to atoms and molecules, but hydrogen ions (thermal protons) penetrate through them. We show that monolayers of graphene and boron nitride can be used to separate hydrogen ion isotopes. Employing electrical measurements and mass spectrometry, we find that deuterons permeate through these crystals much slower than protons, resulting in a separation factor of ~10 at room temperature. The isotope effect is attributed to a difference of about 60 meV between zero-point energies of incident protons and deuterons, which translates into the equivalent difference in the activation barriers posed by two dimensional crystals. In addition to providing insight into the proton transport mechanism, the demonstrated approach offers a competitive and scalable way for hydrogen isotope enrichment.
description: early version of an accepted report
Cost Minimizing Online Algorithms for Energy Storage Management with Worst-case Guarantee
Creators: name: Chau, Chi-Kin
name: Zhang, Guanglin
name: Chen, Minghua
Publisher: name: arXiv
Year: 2015
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: Optimization and Control (math.OC)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: The fluctuations of electricity prices in demand response schemes and intermittency of renewable energy supplies necessitate the adoption of energy storage in microgrids. However, it is challenging to design effective real-time energy storage management strategies that can deliver assured optimality, without being hampered by the uncertainty of volatile electricity prices and renewable energy supplies. This paper presents a simple effective online algorithm for the charging and discharging decisions of energy storage that minimizes the electricity cost in the presence of electricity price fluctuations and renewable energy supplies, without relying on the future information of prices, demands or renewable energy supplies. The proposed algorithm is supported by a near-best worst-case guarantee (i.e., competitive ratio), as compared to the offline optimal decisions based on full future information. Furthermore, the algorithm can be adapted to take advantage of limited future information, if available. By simulations on real-world data, it is observed that the proposed algorithms can achieve satisfactory outcome in practice.
description: To appear in IEEE Transactions on Smart Grid
title: Ultrasonography mapping combined with mammography before breast conserving surgery for primary breast cancer with microcalcifications: a novel approach
Creators: name: Akaike, Gensuke
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Breast
subject: Oncology
subject: Professional issues
subject: Ultrasound
subject: Mammography
subject: MR
subject: Safety
subject: Teleradiology
subject: Education
subject: Image registration
subject: Workforce
subject: Pathology

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Preoperative evaluation of breast cancer with a prominent intraductal component shown by microcalcifications on mammography (MG) is challenging because microcalcifications sometimes spread beyond the lesions which are detectable by US....
Switching between attractive and repulsive Coulomb-interaction-mediated drag in an ambipolar GaAs/AlGaAs bilayer device
Creators: name: Zheng, B.
name: Croxall, A. F.
name: Waldie, J.
name: Gupta, K. Das
name: Sfigakis, F.
name: Farrer, I.
name: Beere, H. E.
name: Ritchie, D. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present measurements of Coulomb drag in an ambipolar GaAs/AlGaAs double quantum well structure that can be configured as both an electron-hole bilayer and a hole-hole bilayer, with an insulating barrier of only 10 nm between the two quantum wells. The Coulomb drag resistivity is a direct measure of the strength of the interlayer particle-particle interactions. We explore the strongly interacting regime of low carrier densities (2D interaction parameter $r_s$ up to 14). Our ambipolar device design allows comparison between the effects of the attractive electron-hole and repulsive hole-hole interactions, and also shows the effects of the different effective masses of electrons and holes in GaAs.
description: 4 pages, 3 figures
Exponential decay rate of partial autocorrelation coefficients of ARMA and short-memory processes
Creators: name: Takemura, Akimichi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics
subject: 60G12

description: We present a short proof of the fact that the exponential decay rate of partial autocorrelation coefficients of a short-memory process, in particular an ARMA process, is equal to the exponential decay rate of the coefficients of its infinite autoregressive representation.
title: Whole-body diffusion-weighted MRI for detection and evaluation of operability in recurrent ovarian cancer as compared with CT
Creators: name: Michielsen, Katrijn
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Genital / Reproductive system female
subject: Oncology
subject: MR-Diffusion/Perfusion
subject: Comparative studies
subject: Imaging sequences
subject: Surgery
subject: Metastases
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Introduction Ovarian cancer still accounts for more than 50% of deaths from all gynaecological malignancies [1]. Survival rate is related to remaining disease after cytoreductive surgery. Despite improved surgical techniques and chemotherapeutic...
title: Clinical applications of arterial spin labeling perfusion in diagnosis of neoplastic brain lesions
Creators: name: Bjelan, Mladen
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Neoplasia
subject: Diagnostic procedure
subject: MR-Diffusion/Perfusion
subject: MR
subject: Oncology
subject: Neuroradiology brain

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The aim of this educational poster is to emphasize the possibilities of arterial spin labeling perfusion (ASL) imaging in an assessment of perfusion in different types of primary brain tumors. We want to point out the possibility of ASL as a...
UNC Counseling and Wellness Services: Development of a Curriculum to Promote Healthy Relationships and Prevent Intimate Partner Violence Among Undergraduate Students at UNC-CH
Creators: name: Okereke, Ije
name: Stankard, Petra
name: Copeland, Lesley
name: Larsen, Rachel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Background: Research shows that as much as 82% of college students report perpetrating verbal abuse against a dating partner and 21% report perpetrating physical abuse. Experience of dating abuse has been associated with a number of negative health outcomes including physical injury, illegal drug use, depression, anxiety, and cognitive impairment. The Counseling and Wellness Services (CWS) Capstone team at the University of North Carolina at Chapel Hill (UNC-CH) aimed to address this public health problem of dating abuse among college students by developing a curriculum for preventing intimate partner violence (IPV), specifically among undergraduate students at UNC-CH. Methods: Our Capstone project included a review of the literature to assess predictors of IPV and evidence-based interventions to prevent IPV. We conducted formative research on healthy dating relationships through focus groups and interviews with UNC-CH undergraduate students, UNC-CH staff, and staff members at neighboring universities (Duke, Elon, NC State). Using findings from the literature review and formative research, we developed a conceptual model of constructs to be targeted by the curriculum in order to promote healthy relationships and prevent IPV. This conceptual model guided the development of our IPV prevention curriculum. Results: The activities resulted in four deliverables: a report of findings from literature review, a report of findings from formative research, a conceptual model, and an IPV prevention curriculum. The curriculum targets five main constructs, namely norms related to gender and alcohol, dating attitudes, communication about relationship expectations, stress management, and conflict management. Impacts and Benefits: We hope that this curriculum will prevent IPV among undergraduate students at UNC-CH and enhance their ability to develop and maintain healthy dating relationships. By preventing IPV, we also hope to prevent the associated negative health outcomes.
title: Diagnostic value of combined CT and SPECT imaging in diagnosis of aхillary lymph node invasion by breast cancer
Creators: name: Krzhivitskiy, Pavel
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Breast
subject: Oncology
subject: Lymph nodes
subject: SPECT-CT
subject: CT
subject: Nuclear medicine conventional
subject: Molecular imaging
subject: Diagnostic procedure
subject: Cancer
subject: Metastases

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: to compare diagnostic accuracy of conventional computerized tomography (CT) and SPECT-CT in lymph node (LN) staging of patients (pts) with breast cancer...
Synthetic activity indicators for M-type dwarf stars
Creators: name: Wedemeyer, Sven
name: Ludwig, Hans-Günter
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Here, we present a set of time-dependent 3D RMHD simulations of a M-dwarf star representative of AD Leo, which extend from the upper convection zone into the chromosphere. The 3D model atmospheres are characterized by a very dynamic and intermittent structure on small spatial and temporal scales and a wealth of physical processes, which by nature cannot be described by means of 1D static model atmospheres. Artificial observations of these models imply that a combination of complementary diagnostics such as Ca II lines and the continuum intensity from UV to millimeter wavelengths, probe various properties of the dynamics, thermal and magnetic structure of the photosphere and the chromosphere and thus provide measures of stellar activity, which can be compared to observations. The complicated magnetic field structure and its imprint in synthetic diagnostics may have important implications for the understanding and characterization of stellar activity and with it possibly for the evaluation of planetary habitability around active M-dwarf stars.
description: Proceedings of IAU Symposium 320 (Impacts of Solar and Stellar Flares on Atmospheres, Coronae and Winds), IAU GA, Honolulu, USA, August 2015; 6 pages, 3 figures (accepted January 2nd, 2016)
title: Acoustic radiation force impulse imaging value in differentiating benign and malignant breast nodules
Creators: name: Magalhaes, Mafalda
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Breast
subject: Oncology
subject: Ultrasound
subject: Elastography
subject: Diagnostic procedure
subject: Neoplasia

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Acoustic Radiation Force Impulse (ARFI) is a new sonographic technology that noninvasively assesses qualitative and quantitative tissue elasticity by measuring shear-wave velocities of a selected region of interest (ROI) (1,2,3) (Fig 1 ). The aim of...
Additional file 1 of Genes to specialized metabolites: accumulation of scopoletin, umbelliferone and their glycosides in natural populations of Arabidopsis thaliana
Creators: name: Ihnatowicz, Anna
name: Siwinska, Joanna
name: Perkowska, Izabela
name: Grosjean, Jeremy
name: Hehn, Alain
name: Bourgaud, Frederic
name: Lojkowska, Ewa
name: Olry, Alexandre
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 1_Table S1. The gene-specific primers used for qPCRs
title: Comparison of diffusion tensor, dynamic susceptibility contrast MRI and 99mTc-Tetrofosmin brain SPECT for the detection of recurrent high-grade glioma
Creators: name: Zikou, Anastasia
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: CNS
subject: Oncology
subject: Nuclear medicine
subject: MR
subject: SPECT
subject: MR-Diffusion/Perfusion
subject: Diagnostic procedure
subject: Imaging sequences
subject: Radiation therapy / Oncology
subject: Neoplasia

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Malignant gliomas are the most common type of primary brain tumor and carry a dismal prognosis. Glioblastoma (GBM) usually has a rapid and fatal clinical course, with a 27.2% overall survival at 2 years ( 1 ). The standard of care for newly...
Polyurethane spray coating of aluminum wire bonds to prevent corrosion and suppress resonant oscillations
Creators: name: Izen, Joseph M.
name: Kurth, Matthew
name: Boyd, Rusty
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Unencapsulated aluminum wedge wire bonds are common in particle physics pixel and strip detectors. Industry-favored bulk encapsulation is eschewed due to the range of operating temperatures and radiation. Wire bond failures are a persistent source of tracking-detector failure. Unencapsulated bonds are vulnerable to condensation-induced corrosion, particularly when halides are present. Oscillations from periodic Lorentz forces are documented as another source of wire bond failure. Spray application of polyurethane coatings, performance of polyurethane-coated wire bonds after climate chamber exposure, and resonant properties of polyurethane-coated wire bonds and their resistance to periodic Lorentz forces are under study for use in a future High Luminosity Large Hadron Collider detector such as the ATLAS Inner Tracker upgrade.
An Evaluation of Hemorrhage Control in a Field Environment
Creators: name: Gurganious, Nicholas
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Massive hemorrhage is the number one cause of battlefield mortality
                    followed by tension pneumothorax and airway trauma. As a result of this,
                    hemorrhage control has been at the forefront of battlefield medicine. Lifesaving
                    intervention can be performed at the most basic level of Self Aid Buddy Care.
                    With its success, the civilian population is incorporating hemorrhage control
                    into the echelon of pre-hospital emergency care. Programs, including Stop the
                    Bleed are providing training and education in tourniquet use to the most likely
                    first responders and bystanders. The program, presented through UNC trauma, was
                    assessed for Strengths, Weaknesses, Opportunities and Threats (SWOT). One
                    strength of the program is that it’s nationally recognized. Weaknesses include a
                    lack of training requests and volunteer instructors. Opportunities include
                    increased awareness of potential for mass casualties and improvements in
                    technology. The analysis also looked at threats to the program such as the lack
                    of a certifying assessment. Overall, the programs are vital as tourniquet use
                    has been shown to be an invaluable tool in controlling life threatening
                    hemorrhage.
In silico identification and biological evaluation of a selective MAP4K4 inhibitor against pancreatic cancer
Creators: name: Chang, Chao-Di
name: Chao, Min-Wu
name: Lee, Hsueh-Yun
name: Liu, Yi-Ting
name: Tu, Huang-Ju
name: Lien, Ssu-Ting
name: Lin, Tony Eight
name: Sung, Tzu-Ying
name: Yen, Shih-Chung
name: Huang, Sing-Han
name: Hsu, Kai-Cheng
name: Pan, Shiow-Lin
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Inhibiting a specific target in cancer cells and reducing unwanted side effects has become a promising strategy in pancreatic cancer treatment. MAP4K4 is associated with pancreatic cancer development and correlates with poor clinical outcomes. By phosphorylating MKK4, proteins associated with cell apoptosis and survival are translated. Therefore, inhibiting MAP4K4 activity in pancreatic tumours is a new therapeutic strategy. Herein, we performed a structure-based virtual screening to identify MAP4K4 inhibitors and discovered the compound F389-0746 with a potent inhibition (IC50 120.7 nM). The results of kinase profiling revealed that F389-0746 was highly selective to MAP4K4 and less likely to cause side effects. Results of in vitro experiments showed that F389-0746 significantly suppressed cancer cell growth and viability. Results of in vivo experiments showed that F389-0746 displayed comparable tumour growth inhibition with the group treated with gemcitabine. These findings suggest that F389-0746 has promising potential to be further developed as a novel pancreatic cancer treatment. HighlightsWe identified a novel MAP4K4 inhibitor using a structure-based virtual screening strategy.Kinase profiling showed high selectivity towards MAP4K4.The identified inhibitor suppressed pancreatic cancer cell growth and viability in vitro.The inhibitor downregulated the MKK4-JNK signalling pathway.The inhibitor suppressed tumour growth in vivo. We identified a novel MAP4K4 inhibitor using a structure-based virtual screening strategy. Kinase profiling showed high selectivity towards MAP4K4. The identified inhibitor suppressed pancreatic cancer cell growth and viability in vitro. The inhibitor downregulated the MKK4-JNK signalling pathway. The inhibitor suppressed tumour growth in vivo.
Investigating the regulation of ribosomal protein S6 kinase 1 by CoAlation.
Creators: name: Malanchuk, Oksana
name: Bdzhola, Anna
name: Palchevskyi, Sergii
name: Bdzhola, Volodymyr
name: Chai, Peng
name: Pardo, Olivier E
name: Seckl, Michael J
name: Banerjee, Adrija
name: Peak-Chew, Sew Yeu
name: Skehel, Mark
name: Guruprasad, Lalitha
name: Zhyvoloup, Alexander
name: Gout, Ivan
name: Filonenko, Valeriy
Publisher: name: The Francis Crick Institute
Year: 2024
Subjects: classificationCode: Biochemistry & Proteomics
subject: Biochemistry & Proteomics
classificationCode: Chemical Biology & High Throughput
subject: Chemical Biology & High Throughput
classificationCode: Computational & Systems Biology
subject: Computational & Systems Biology

description: Ribosomal protein S6 kinases belong to a family of highly conserved enzymes in eukaryotes that regulate cell growth, proliferation, survival, and the stress response. It is well established that the activation and downstream signalling of p70S6Ks involve multiple phosphorylation events by key regulators of cell growth, survival, and energy metabolism. Here, we report for the first time the covalent modification of p70S6K1 by coenzyme A (CoA) in response to oxidative stress, which regulates its kinase activity. The site of CoA binding (CoAlation) was mapped by mass spectrometry to cysteine 217 (Cys217), located in the kinase activation loop and only one amino acid away from the tripeptide DFG motif, which facilitates ATP-binding. The CoAlation of recombinant p70S6K1 was demonstrated in vitro and was shown to inhibit its kinase activity. Our molecular docking and dynamics analysis revealed the most likely mode for CoA binding to p70S6K1. This mechanism involves the non-covalent binding of the CoA ADP moiety to the p70S6K1 nucleotide-binding pocket, positioning the CoA thiol group in close proximity to form a covalent bond with the surface-exposed Cys217 residue. These findings support a "dual anchor" mechanism for protein kinase inhibition by CoAlation in cellular response to oxidative stress. Furthermore, the inhibition of S6K1 by CoAlation may open new avenues for developing novel inhibitors.
Meta-Analysis Looking at Over 20 Years of Boundary Management Research
Creators: name: Mueller, Nicolas
name: Brueggemann, Jonas
name: Schumacher, Svenja
name: Kempen, Regina
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Industrial and Organizational Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: boundary management
subject: integration
subject: meta-analysis
subject: segmentation
subject: work–nonwork

description: This meta-analysis aims to synthesize the associations between boundary management variables (i.e., preferences and enactment) and (a) negative cross-role spillover (i.e., conflict or interference), (b) positive cross-role spillover (i.e., enrichment, enhancement, or facilitation), (c) job satisfaction, (d) turnover intentions, (e) exhaustion, (f) detachment from work, and (g) life-domain balance. Furthermore, the meta-analysis examines possible moderators to determine the source of heterogeneity in effect sizes.
title: PET/CT versus contrast enhanced CT in the initial assessment and follow up of Thoracic Lymphoma
Creators: name: ElNayal, Amr
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Oncology
subject: Lymph nodes
subject: Thorax
subject: PET-CT
subject: CT
subject: Comparative studies
subject: Lymphoma

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Intrathoracic disease is observed in about 70–85% of Hodgkin’s disease patients and in 25–50% of those with Non Hodgkin’s lymphoma; it is characterized byare characterized by enlargement of mediastinal lymph nodes, parenchymal...
Expression of Negative Affect Through Insincere Survey Response in the 2016 U.S. Presidential Primary Elections
Creators: name: Harris, Matt
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: Data for the project: Expression of Negative Affect Through Insincere Survey Response in the 2016 U.S. Presidential Primary Elections. For coding questions contact Matt Harris, mharris@park.edu
title: How useful is 18F-FDG PET-CT in the management of fever of unknown origin? – prospective multicentre study
Creators: name: Sonoda, Luke
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Oncology
subject: Haematologic
subject: Nuclear medicine
subject: PET-CT
subject: Diagnostic procedure
subject: Connective tissue disorders
subject: Infection
subject: Inflammation

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: 18 F-FDG-PET-CT (PET-CT) plays an important role in the management of fever of unknown origin (FUO). The aim of this study is to demonstrate the diagnostic accuracy of PET-CT in patients with...
Recommending Scientific Papers: A Survey and A Hybrid Approach
Creators: name: Bouziotopoulos, Grigoris
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2023
Subjects: subject: Paper Recommendation, Paper Recommendation Survey, Graph-based Recommendation Systems, Hybrid Recommendation Systems

description: Μ.Δ.Ε. 91
description: Paper recommendation systems are important tools for helping scholars and researchers discover relevant and interesting papers in the face of the growing volume of published research. In this study, we conduct a survey of paper recommendation approaches and evaluate the performance of our own implementation, the ExtendedPaperVeTo recommender. Our survey covers a range of approaches and studies, and identifies common trends and challenges in the field. Our implementation evaluation compares the performance of the ExtendedPaperVeTo approach to two other approaches, the MongoFTS and PaperVeTo approaches, using various evaluation metrics. Our findings indicate that hybrid approaches are the most common type of paper recommendation approach (PRA) used in the reviewed studies, followed by content-based filtering, graph-based approaches, and collaborative filtering. However, we also identify several challenges and limitations in the current state of the field, including the lack of reproducibility and scalability of many approaches, the limited consideration of the operator’s perspective and user characteristics, and the reliance on offline evaluations. In our implementation evaluation, we observe that the ExtendedPaperVeTo approach was slightly outperformed by the MongoFTS approach in terms of NDCG and AR scores, but performed better than the PaperVeTo approach. In the conclusion, we discuss potential directions for future research that could address the challenges and limitations identified in our survey and implementation evaluation.
Use of The Mediterranean Diet to Manage Progression of Type 2 Diabetes
Creators: name: Orange, Christopher
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Introduction:
The various aspects that comprise metabolic syndrome such as pre-diabetes,
dyslipidemia and pre-hypertension epitomize prodromal phases of severe cardiometabolic
disorders.1 Lifestyle modifications have demonstrated the ability to mitigate or arrest the
subsequent advancement of various components of metabolic syndrome. The cardio protective
benefits of the adoption of the Mediterranean diet have been well established in the medical
literature. But can this supposed panacea be more effective in preventing the progression from
pre-diabetes to type 2 diabetes than traditional pharmacological interventions such as the use
of Metformin? That is what this paper will endeavor to ascertain.
Measurement of the I=1/2 $K π$ $\mathcal{S}$-wave amplitude from Dalitz plot analyses of $η_c \to K \bar K π$ in two-photon interactions
Creators: name: The BABAR Collaboration
name: Lees, J. P.
name: Others
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We study the processes $γγ\to K^0_S K^{\pm}π^{\mp}$ and $γγ\to K^+ K^- π^0$ using a data sample of 519~$fb^{-1}$ recorded with the BaBar detector operating at the SLAC PEP-II asymmetric-energy $e^+ e^-$ collider at center-of-mass energies at and near the $Υ(nS)$ ($n = 2,3,4$) resonances. We observe $η_c$ decays to both final states and perform Dalitz plot analyses using a model-independent partial wave analysis technique. This allows a model-independent measurement of the mass-dependence of the $I=1/2$ $K π$ $\mathcal{S}$-wave amplitude and phase. A comparison between the present measurement and those from previous experiments indicates similar behaviour for the phase up to a mass of 1.5 $GeV/c^2$. In contrast, the amplitudes show very marked differences. The data require the presence of a new $a_0(1950)$ resonance with parameters $m=1931 \pm 14 \pm 22 \ MeV/c^2$ and $Γ=271 \pm 22 \pm 29 \ MeV$.
description: 20 pages, 14 postscript figures, Submitted to Phys. Rev. D
title: Quantitative and qualitative parameters derived from DCE-MRI in rectal cancer: Is there a correlation?
Creators: name: Martens, Milou
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Pelvis
subject: Oncology
subject: Gastrointestinal tract
subject: MR
subject: MR-Diffusion/Perfusion
subject: Contrast agent-intravenous
subject: Neoplasia
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Recently several studies have been performed using dynamic contrast enhanced MRI (DCE-MRI) in the response prediction for rectal cancer. Most studies used standardized quantitative parameters (Ktrans Kep), while some studies calculated their own...
Pre-registration and pre-analysis plan: Norms against commodification of land and body, formal institutions and historical preconditions
Creators: name: Nosenzo, Daniele
name: Casari, Marco
name: Fabbri, Marco
name: Limata, Plinio
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Economics
subject: Social and Behavioral Sciences

description: Our main goal is to test the hypothesis that the introduction of a market-like institution that aims at facilitating the trade of land (a land tenure reform establishing formal property rights in Benin), weakens the norms against commodification of land and human body. We are also interested in the role of historical conditions - namely the degree of exposure to slave trade raids during XVI-XIX centuries - in shaping the norms against commodification.
title: Comparison of whole-body DWI and conventional methods for treatment monitoring at patients with breast cancer
Creators: name: Trofimenko, Irina
Publisher: name: European Congress of Radiology
Year: 2014
Subjects: subject: Oncology
subject: MR
subject: MR-Diffusion/Perfusion
subject: Diagnostic procedure
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Nowadays at our institution the follow up scheme for patients with breast cancer after the treatment includes CT of thorax, abdomen and pelvis; sometimes (if patient has a bone pain or CT reveals the bone lesions) it is followed by bone scan with...
Graph Neural Networks on SPD Manifolds for Motor Imagery Classification: A Perspective from the Time-Frequency Analysis
Creators: name: Ju, Ce
name: Guan, Cuntai
Publisher: name: arXiv
Year: 2022
Subjects: subject: Signal Processing (eess.SP)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: I.2.0

description: The motor imagery (MI) classification has been a prominent research topic in brain-computer interfaces based on electroencephalography (EEG). Over the past few decades, the performance of MI-EEG classifiers has seen gradual enhancement. In this study, we amplify the geometric deep learning-based MI-EEG classifiers from the perspective of time-frequency analysis, introducing a new architecture called Graph-CSPNet. We refer to this category of classifiers as Geometric Classifiers, highlighting their foundation in differential geometry stemming from EEG spatial covariance matrices. Graph-CSPNet utilizes novel manifold-valued graph convolutional techniques to capture the EEG features in the time-frequency domain, offering heightened flexibility in signal segmentation for capturing localized fluctuations. To evaluate the effectiveness of Graph-CSPNet, we employ five commonly-used publicly available MI-EEG datasets, achieving near-optimal classification accuracies in nine out of eleven scenarios. The Python repository can be found at https://github.com/GeometricBCI/Tensor-CSPNet-and-Graph-CSPNet.
description: 15 pages, 5 figures, 6 Tables; This work has been accepted by the IEEE Transactions on Neural Networks and Learning Systems, 2023. Copyright will be transferred without notice, after which this version may no longer be accessible
Phase Transitions in Semidefinite Relaxations
Creators: name: Javanmard, Adel
name: Montanari, Andrea
name: Ricci-Tersenghi, Federico
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Discrete Mathematics (cs.DM)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Statistical inference problems arising within signal processing, data mining, and machine learning naturally give rise to hard combinatorial optimization problems. These problems become intractable when the dimensionality of the data is large, as is often the case for modern datasets. A popular idea is to construct convex relaxations of these combinatorial problems, which can be solved efficiently for large scale datasets. Semidefinite programming (SDP) relaxations are among the most powerful methods in this family, and are surprisingly well-suited for a broad range of problems where data take the form of matrices or graphs. It has been observed several times that, when the `statistical noise' is small enough, SDP relaxations correctly detect the underlying combinatorial structures. In this paper we develop asymptotic predictions for several `detection thresholds,' as well as for the estimation error above these thresholds. We study some classical SDP relaxations for statistical problems motivated by graph synchronization and community detection in networks. We map these optimization problems to statistical mechanics models with vector spins, and use non-rigorous techniques from statistical mechanics to characterize the corresponding phase transitions. Our results clarify the effectiveness of SDP relaxations in solving high-dimensional statistical problems.
description: 71 pages, 24 pdf figures