cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A2A receptors and methamphetamine toxicity: a role of adenosine as an endogenous neurotoxin
Creators: name: Scatena, Alessia
name: Ferrucci, Michela
name: Soldani, Paola
name: Paparelli, Silvio
name: Da Settimo, Federico
name: Paparelli, Antonio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: adenosine receptors A2A; methamphetamine; autophagy; neurodegeneration; dopamine

description: Adenosine A2A are a class of purinergic receptors largely expressed in dopamine (DA)-rich areas of the central nervous system. In particular, they are abundant within basal ganglia, where they modulate the activity of various neurotransmitters, including DA. Despite the lack of knowledge on their fine physiological mechanisms, it is worth to mention that A2A antagonists prevent neuronal death and dyskinesia in Parkinsonism. Moreover the neuroprotective effects observed after blockade of adenosine A2A receptors in several models of neurotoxicity suggests a toxic effect for endogenous adenosine In the light of these evidences, in the present study, by using in vitro models of DA neurons, we investigated: (i) whether A2A antagonists protect DA containing neurons against methamphetamine (METH); (ii) whether activation of A2A receptors produce neurodegeneration. This was done either using A2A agonist receptor NECA or the endogenous compound adenosine; (iii) whether specific cell mechanisms are involved in these phenomena. We found that A2A antagonists protect DA cells against METH neurotoxicity. Moreover, we found that NECA and adenosine both produced a toxic effects. In the light of the key role of autophagy in modulating the survival of DA neurons we found that A2A antagonists increase, while A2A agonists decrease, autophagy. These results suggest that neuroprotection induced by A2A antagonists may be mediated by enhancement of autophagy. As expected we found that pre-treatment with a non-adenosine related inducer of autophagy produced the same protective effects obtained with A2A antagonists. Our data indicate for the first time, that A2A antagonists are protective in DA neurons against METH. Such an effect appear to be mediated by the enhancement of autophagy. On the other hand we found that activation of A2A receptor produces neurotoxicity. Interestingly these effects was reproduced by administering endogenous adenosine. This suggests that adenosine may produce neurodegeneration by inhibiting the autophagy pathway.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
Compact graphene mode-locked wavelength-tunable erbium-doped fiber lasers: from all anomalous dispersion towards all normal dispersion
Creators: name: Zhang, Han
name: Tang, Dingyuan
name: Zhao, Luming
name: Bao, Qiaoliang
name: Loh, Kian Ping
name: Lin, Bo
name: Tjin, Swee Chuan
Publisher: name: arXiv
Year: 2010
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Soliton operation and soliton wavelength tuning of erbium-doped fiber lasers mode locked with atomic layer graphene was experimentally investigated under various cavity dispersion conditions. It was shown that not only wide range soliton wavelength tuning but also soltion pulse width variation could be obtained in the fiber lasers. Our results show that the graphene mode locked erbium-doped fiber lasers provide a compact, user friendly and low cost wavelength tunable ultrahsort pulse source.
Production of nitric oxide and peroxynitrite by human spermatozoa: a role in male infertility?
Creators: name: Salvolini, Eleonora
name: Vignini, Arianna
name: Lucarini, Guendalina
name: Buldreghini, Eddi
name: Orciani, Monia
name: Balercia, Giancarlo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: Asthenozoospermia; nitric oxide; nitrotyrosine; peroxynitrite

description: A growing body of evidence confirms the importance of oxidative stress in male infertility (Agarwal and Saleh, 2002). Spermatozoa generate small amounts of O2·- and nitric oxide (NO), that, at high concentrations, combine to produce peroxynitrite, which can rapidly react with proteins, lipids, and DNA. In particular, the nitration of protein residues gives rise to 3-nitrotyrosine, a widely used marker of peroxynitrite production. NO is produced by three isoforms of NO synthase (NOS). The inducible NOS (iNOS) seems to negatively affect sperm function through the production of large amounts of NO (Yang et al., 2005). Our aim was to determine NO and ONOO- production in semen samples from fertile donors and infertile patients affected by idiopathic asthenozoospermia, as well as their correlation with sperm cell kinetic features; in addition we evaluated the tyrosine nitration in the same samples, to clarify any pathogenic involvement in sperm cell functional impairment. Furthermore, we assessed the expression of iNOS by means of immunohistochemical and Western blot analyses. NO and ONOO- production was significantly lower in controls than in asthenozoospermic patients and inversely correlated with the kinetic parameters. Moreover, the Western immunoblots showed an increase in tyrosine nitration and iNOS expression in the asthenozoospermic samples, in agreement with immunohistochemical findings. The present data confirm a critical negative effect of NO and peroxynitrite on sperm cell motility, supporting the role of an increased NOS activity, and an excess of tyrosine nitration in the pathogenesis of idiopathic asthenozoospermia that causes male infertility.
description: Italian Journal of Anatomy and Embryology, Vol 117, No 2 (Supplement) 2012
Additional file 3 of Factors associated with viremia in people living with HIV on antiretroviral therapy in Guatemala
Creators: name: Ortíz, Dean W.
name: Roberts-Sano, Olivia
name: Marroquin, Hugo E.
name: Larson, Lindsey
name: Franco, Katherine B.
name: Spec, Andrej
name: Melendez, Johanna R.
name: Pinzón, Rodolfo
name: Samayoa, Ana J.
name: Mejia-Chew, Carlos
name: O´Halloran, Jane A.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 3: Table S3. Reasons for perceived difficulty attending HIV care in 258 PLHIV on ART in Guatemala.
The Hayabusa Spacecraft Asteroid Multi-Band Imaging Camera: AMICA
Creators: name: Ishiguro, Masateru
name: Nakamura, Ryosuke
name: Tholen, David J.
name: Hirata, Naru
name: Demura, Hirohide
name: Nemoto, Etsuko
name: Nakamura, Akiko M.
name: Higuchi, Yuta
name: Sogame, Akito
name: Yamamoto, Aya
name: Kitazato, Kohei
name: Yokota, Yasuhiro
name: Kubota, Takashi
name: Hashimoto, Tatsuaki
name: Saito, Jun
Publisher: name: arXiv
Year: 2009
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The Hayabusa Spacecraft Asteroid Multiband Imaging Camera (AMICA) has acquired more than 1400 multispectral and high-resolution images of its target asteroid, 25143 Itokawa, since late August 2005. In this paper, we summarize the design and performance of AMICA. In addition, we describe the calibration methods, assumptions, and models, based on measurements. Major calibration steps include corrections for linearity and modeling and subtraction of bias, dark current, read-out smear, and pixel-to-pixel responsivity variations. AMICA v-band data were calibrated to radiance using in-flight stellar observations. The other band data were calibrated to reflectance by comparing them to ground-based observations to avoid the uncertainty of the solar irradiation in those bands. We found that the AMICA signal was linear with respect to the input signal to an accuracy of << 1% when the signal level was < 3800 DN. We verified that the absolute radiance calibration of the AMICA v-band (0.55 micron) was accurate to 4% or less, the accuracy of the disk-integrated spectra with respect to the AMICA v-band was about 1%, and the pixel-to-pixel responsivity (flatfield) variation was 3% or less. The uncertainty in background zero-level was 5 DN. From wide-band observations of star clusters, we found that the AMICA optics have an effective focal length of 120.80 \pm 0.03 mm, yielding a field-of-view (FOV) of 5.83 deg x 5.69 deg. The resulting geometric distortion model was accurate to within a third of a pixel. We demonstrated an image-restoration technique using the point-spread functions of stars, and confirmed that the technique functions well in all loss-less images. An artifact not corrected by this calibration is scattered light associated with bright disks in the FOV.
description: 107 pages, 22 figures, 9 tables. will appear in Icarus
Paths and partitions: combinatorial descriptions of the parafermionic states
Creators: name: Mathieu, Pierre
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: Combinatorics (math.CO)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: The Z_k parafermionic conformal field theories, despite the relative complexity of their modes algebra, offer the simplest context for the study of the bases of states and their different combinatorial representations. Three bases are known. The classic one is given by strings of the fundamental parafermionic operators whose sequences of modes are in correspondence with restricted partitions with parts at distance k-1 differing at least by 2. Another basis is expressed in terms of the ordered modes of the k-1 different parafermionic fields, which are in correspondence with the so-called multiple partitions. Both types of partitions have a natural (Bressoud) path representation. Finally, a third basis, formulated in terms of different paths, is inherited from the solution of the restricted solid-on-solid model of Andrews-Baxter-Forrester. The aim of this work is to review, in a unified and pedagogical exposition, these four different combinatorial representations of the states of the Z_k parafermionic models. The first part of this article presents the different paths and partitions and their bijective relations; it is purely combinatorial, self-contained and elementary; it can be read independently of the conformal-field-theory applications. The second part links this combinatorial analysis with the bases of states of the Z_k parafermionic theories. With the prototypical example of the parafermionic models worked out in detail, this analysis contributes to fix some foundations for the combinatorial study of more complicated theories. Indeed, as we briefly indicate in ending, generalized versions of both the Bressoud and the Andrews-Baxter-Forrester paths emerge naturally in the description of the minimal models.
description: 53 pages (v2: minor modifications,v3: 3 typos corrected); to appear in the special issue of J. Math. Phys. on "Integrable Quantum Systems and Solvable Statistical Mechanics Models."
Applying value-based decision making to address conflicts over social housing projects : the case of the Terwillegar Housing Project in Edmonton, Alberta
Creators: name: Lo, Patrick Wai Yan
Publisher: name: The University of British Columbia
Year: 2016

description: This Professional Planning Project paper proposes a value-based decision-making process for decisions on social housing projects, with the intention of trying to address the conflicts that alltoo- often occur between stakeholders with differing opinions and values. Drawing upon concepts in the literature on value-based decision making and conflicts over social housing projects, the author developed a framework for this value-based decision-making process, and hypothetically applied it to the case of the controversial Terwillegar housing project in Edmonton, Alberta.
Sialic acids and hyaluronan expression in the renal tubulointerstitial space of rat in an experimental sepsis model
Creators: name: Sgambati, Eleonora
name: Adembri, Chiara
name: Nosi, Daniele
name: Tani, Alessia
name: Santoro, Giovanna
name: Zappoli Thyrion, Giorgia D.
name: Selmi, Valentina
name: Vitali, Luca
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: Sialic acids; hyaluronan; sepsis; renal tubulointerstitial space

description: Sialic acids and hyaluronan play important roles in maintaining structure and functionality of the kidney tubulointerstitial space. In several investigations, performed on some renal pathologies, morpho-functional changes of the tubulointerstitial space showed correlation with altered expression of these anionic components; no data are available on the expression of these molecules in this space during sepsis. Therefore, the aim of this study was to evaluate the expression of sialic acids and hyaluronan in the renal tubulointerstitial space in the early stages of an experimental animal model of polymicrobial sepsis. Experiments were performed on adult male rats assigned to two groups: 1) sham-operated (n=20); 2) Caecal Ligation and Puncture (CLP) (clinically model of polymicrobial infection that mimics human sepsis) (n=25). The groups were divided into 3 subgroups related to 3 time points after CLP or sham-operated: t1=0 h, t2=3 h and t3=7 h. For evidence of sepsis TNF-α plasma level was measured and microbiology of peritoneal fluid was examined with bacteriologic techniques. Urinary protein levels were measured to test the renal functional damage. Kidney samples of each group were processed to analyse the morphology, sialic acids expression, by using lectin histochemistry, and hyaluronan expression, by using immunohistochemistry. The results showed that plasma TNF-α level significantly increased after CLP induction when compared to sham-operated animals. Bacteriologic techniques revealed a polymicrobial infection after CLP. The proteinuria was significantly increased in CLP group. Morphological changes, such as edema and epithelial lesions, were observed in the tubulointerstitium space in CLP group. Lectin histochemistry showed decrease of sialic acids in the tubular wall of septic rats with respect to the control ones. The largest amount of acetylated sialic acid was evidenced in the sepsis group. Immunohistochemistry demonstrated hyaluronan presence only in the medullary interstitium in the control group; in the septic rats hyaluronan appeared also in the cortical interstitium and tubular wall. The findings indicate the existence of a correlation between sialic acids and hyaluronan altered expression and morpho-functional changes in the kidney tubulointerstitial space during sepsis. In addition, an important role of these anionic molecules in protection/ defence and repairing processes may be suggested.
description: Italian Journal of Anatomy and Embryology, Vol 117, No 2 (Supplement) 2012
The claustrum and its projection system in the human brain: a tractographic anatomical study
Creators: name: Trimarchi, Fabio
name: Milardi, Demetrio
name: Arrigo, Alessandro
name: Duca, Antonio
name: Vaccarino, Gianluigi
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: Claustrum; DTI; fMRI; working memory

description: The claustrum is a thin, irregular, sheet-like neuronal structure allocated between internal capsule and external capsule included between the deep face of insula and the lenticular nucleus of striatus. Anatomically we classify claustrum in basal ganglia also if differs from them for its relationship with neocortex in absence of thalamic connections. Claustrum in animal functionally is a polisensorial integration system and has demonstrated several potential sources of somatosensory and visual inputs to auditory and motor cortex. Claustrum is considered like a possible connection among such systems and working memory process. The existence of cross-modal associations indicates a single target persecuted by functionally different cerebral areas. The entire study was performed using a 3T Achieva Philips scanner; a SENSE 8 channels head coil, acquiring T1 weighted 3D TFE , DTI sequence and finally fMRI sequences on five healthy subjects. Using DTI tecnique in this study we examined the claustrum and its projection to neocortex and with a fMRI task based on “filtered answer” we analyzed activaton of claustrum and cerebral cortex. From results, aside animal cases already studied in present literature, we put in evidence not only a “claustrum-cortex” connection but also a “claustrum-claustrum- ipsilateral cortex” one. Such result looks like related to the performed “filtered answer” motor task.
description: Italian Journal of Anatomy and Embryology, Vol 117, No 2 (Supplement) 2012
title: ÐÑÐ³Ð¾Ð³Ð°ÑÐ¸ÑÐµÐ»ÑÐ½Ð¾Ðµ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð¾ ÑÐ»ÐµÐ³Ð°Ð·Ð¾Ð²Ð¾Ð³Ð¾ Ð°Ð²ÑÐ¾ÐºÐ¾Ð¼Ð¿ÑÐµÑÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð²ÑÐºÐ»ÑÑÐ°ÑÐµÐ»Ñ 220ÐºÐ, 63ÐºÐ
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð¤ÐµÑÐ¸ÑÐ¾Ð², ÐÐ¼Ð¸ÑÑÐ¸Ð¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: ÑÐ»ÐµÐ³Ð°Ð·Ð¾Ð²ÑÐ¹ Ð²ÑÐºÐ»ÑÑÐ°ÑÐµÐ»Ñ
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high-voltage SF6 circuit-breaker
puffer-type arc-chamber
hydraulical drive

description: Ð ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÐ»ÐµÐ³Ð°Ð·Ð¾Ð²ÑÐµ Ð²ÑÐºÐ»ÑÑÐ°ÑÐµÐ»Ð¸ Ð¿ÐµÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÐ¾ÐºÐ° Ð²ÑÑÐ¾ÐºÐ¾Ð³Ð¾ Ð½Ð°Ð¿ÑÑÐ¶ÐµÐ½Ð¸Ñ 220ÐºÐ, 63ÐºÐ Ð¾ÑÐµÑÐµÑÑÐ²ÐµÐ½Ð½ÑÑ Ð¸ Ð·Ð°ÑÑÐ±ÐµÐ¶Ð½ÑÑ ÑÐ¸ÑÐ¼. ÐÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ñ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð´ÑÐ³Ð¾Ð³Ð°ÑÐ¸ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð° 220ÐºÐ, 63ÐºÐ. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº Ð¸ Ð¾Ð¿ÑÐ¸Ð¼Ð¸Ð·Ð°ÑÐ¸Ñ Ð¾ÑÐ´ÐµÐ»ÑÐ½ÑÑ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð² ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸.
description: High-voltage SF6 circuit-breakers 220kV, 63kA are discussed. Results of development of the puffer-type Arc-Chamber 220kV, 63kA are presented. Adynamic characteristic and optimization of separate elements of thearc-chamber-design have been analyzed.
title: ÐÐµÑÐ¾Ð´Ñ ÑÐ°ÑÑÑÑÐ° Ð´Ð»Ð¸Ð½Ð½ÑÑ Ð»Ð¸Ð½Ð¸Ð¹ Ð¸ ÑÑÑÐ¾Ð¹ÑÐ¸Ð²Ð¾ÑÑÐ¸ ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÐµÐ¿ÐµÐ¹
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÑÐ¿ÑÐ¾Ð², ÐÐ»Ð°Ð´Ð¸Ð¼Ð¸Ñ
name: Ð¡Ð¾ÑÐ°Ð²Ð°, ÐÐ»ÐµÐºÑÐ°Ð½Ð´Ñ
name: ÐÑÐµÑÐ½ÐµÐ²Ð¸ÐºÐ¾Ð², ÐÐ¾Ð½ÑÑÐ°Ð½ÑÐ¸Ð½
Publisher: name: ÐÐÐÐÐ¢ÐÐ¥-ÐÐ ÐÐ¡Ð¡
Year: 2022
Subjects: Ð­Ð»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÑÐµÐ¿Ð¸

description: Ð£ÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²ÑÐµÑ Ð¤ÐÐÐ¡3++/Ð¡Ð£ÐÐ¡ ÑÐµÐ´ÐµÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð°Ð²ÑÐ¾Ð½Ð¾Ð¼Ð½Ð¾Ð³Ð¾ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ ÑÑÑÐµÐ¶Ð´ÐµÐ½Ð¸Ñ Ð²ÑÑÑÐµÐ³Ð¾ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ Â«Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾Â» Ð¿Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸ÑÐ¼ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ¾Ð² 16.03.01 Â«Ð¢ÐµÑÐ½Ð¸ÑÐµÑÐºÐ°Ñ ÑÐ¸Ð·Ð¸ÐºÐ°Â», 11.03.01 Â«Ð Ð°Ð´Ð¸Ð¾ÑÐµÑÐ½Ð¸ÐºÐ°Â», 11.03.02 Â«ÐÐ½ÑÐ¾ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½ÑÐµ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¸ Ð¸ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ²ÑÐ·Ð¸Â», 11.03.04 Â«Ð­Ð»ÐµÐºÑÑÐ¾Ð½Ð¸ÐºÐ° Ð¸ Ð½Ð°Ð½Ð¾ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð¸ÐºÐ°Â». Ð¡Ð¾Ð´ÐµÑÐ¶Ð¸Ñ ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÑÐ²ÐµÐ´ÐµÐ½Ð¸Ñ Ð¸Ð· ÑÐ°Ð·Ð´ÐµÐ»Ð¾Ð² Â«ÐÐ¾Ð»Ð½Ð¾Ð²ÑÐµ Ð¿ÑÐ¾ÑÐµÑÑÑ Ð² ÑÐµÐ¿ÑÑ Ñ ÑÐ°ÑÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð½ÑÐ¼Ð¸ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ°Ð¼Ð¸Â» Ð¸ Â«Ð£ÑÑÐ¾Ð¹ÑÐ¸Ð²Ð¾ÑÑÑ ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÐµÐ¿ÐµÐ¹, ÑÐ¾Ð´ÐµÑÐ¶Ð°ÑÐ¸Ñ Ð°ÐºÑÐ¸Ð²Ð½ÑÐµ ÑÐ»ÐµÐ¼ÐµÐ½ÑÑÂ», Ð° ÑÐ°ÐºÐ¶Ðµ Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ¸ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ñ ÑÐ°ÑÑÑÑÐ¾Ð² ÐºÐ¾Ð»ÐµÐ±Ð°ÑÐµÐ»ÑÐ½ÑÑ Ð¿ÑÐ¾ÑÐµÑÑÐ¾Ð² Ð² Ð´Ð»Ð¸Ð½Ð½ÑÑ Ð»Ð¸Ð½Ð¸ÑÑ Ð¸ ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÐµÐ¿ÑÑ, ÑÐ¾Ð´ÐµÑÐ¶Ð°ÑÐ¸Ñ Ð°ÐºÑÐ¸Ð²Ð½ÑÐµ ÑÐ»ÐµÐ¼ÐµÐ½ÑÑ. ÐÐ¾ÑÐ¾Ð±Ð¸Ðµ Ð¿ÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð¾ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð², Ð¸Ð·ÑÑÐ°ÑÑÐ¸Ñ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½Ñ Â«Ð¢ÐµÐ¾ÑÐ¸Ñ ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÐµÐ¿ÐµÐ¹Â», Â«Ð Ð°Ð´Ð¸Ð¾ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐµÐ¿Ð¸ Ð¸ ÑÐ¸Ð³Ð½Ð°Ð»ÑÂ», Â«Ð¤Ð¸Ð·Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¾ÑÐ½Ð¾Ð²Ñ ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð¸ÐºÐ¸Â», Ð° ÑÐ°ÐºÐ¶Ðµ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð², Ð°ÑÐ¿Ð¸ÑÐ°Ð½ÑÐ¾Ð² Ð¸ Ð¿ÑÐµÐ¿Ð¾Ð´Ð°Ð²Ð°ÑÐµÐ»ÐµÐ¹ ÐÐ½ÑÑÐ¸ÑÑÑÐ° ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð¸ÐºÐ¸ Ð¸ ÑÐµÐ»ÐµÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¹ Ð¡ÐÐ±ÐÐ£, Ð´ÑÑÐ³Ð¸Ñ Ð²ÑÑÑÐ¸Ñ ÑÑÐµÐ±Ð½ÑÑ Ð·Ð°Ð²ÐµÐ´ÐµÐ½Ð¸Ð¹, Ð¾ÑÑÑÐµÑÑÐ²Ð»ÑÑÑÐ¸Ñ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÑ ÑÐ¿ÐµÑÐ¸Ð°Ð»Ð¸ÑÑÐ¾Ð² Ð² Ð¾Ð±Ð»Ð°ÑÑÑÑ ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð¸ÐºÐ¸, ÑÐ°Ð´Ð¸Ð¾ÑÐµÑÐ½Ð¸ÐºÐ¸, Ð¸Ð½ÑÐ¾ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¹.
title: ÐÐ½Ð¶ÐµÐ½ÐµÑÐ½Ð¾Ðµ Ð±Ð»Ð°Ð³Ð¾ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð¾ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ½ÐºÑÐ°
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð¡ÑÐ¾Ð»ÑÑÐ¾Ð², ÐÐ¸ÑÐ°Ð¸Ð»
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ ÑÐµÐ»ÑÐµÑÐ°
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description: ÐÐ°Ð½Ð½Ð°Ñ Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ½Ð¾Ð¼Ñ Ð¸Ð½Ð¶ÐµÐ½ÐµÑÐ½Ð¾Ð¼Ñ Ð±Ð»Ð°Ð³Ð¾ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ñ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ½ÐºÑÐ° Ð² ÐÐµÐ½Ð¸Ð½Ð³ÑÐ°Ð´ÑÐºÐ¾Ð¹ Ð¾Ð±Ð»Ð°ÑÑÐ¸. ÐÐµÑÐ²Ð°Ñ ÑÐ°ÑÑÑ Ð¿ÑÐ¾ÐµÐºÑÐ° Ð²ÐºÐ»ÑÑÐ°ÐµÑ Ð² ÑÐµÐ±Ñ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ ÑÐµÐ»ÑÐµÑÐ° Ð¸ Ð²ÐµÑÑÐ¸ÐºÐ°Ð»ÑÐ½ÑÑ Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²ÐºÑ Ð·Ð°ÑÑÑÐ°Ð¸Ð²Ð°ÐµÐ¼Ð¾Ð¹ ÑÐµÑÑÐ¸ÑÐ¾ÑÐ¸Ð¸, Ð±Ð»Ð°Ð³Ð¾ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð¾ Ð¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ ÑÐ»Ð¸ÑÐ½Ð¾-Ð´Ð¾ÑÐ¾Ð¶Ð½Ð¾Ð¹ ÑÐµÑÐ¸ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ½ÐºÑÐ°, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÑ ÑÐ¸ÑÑÐµÐ¼ Ð¸Ð½Ð¶ÐµÐ½ÐµÑÐ½Ð¾Ð¹ Ð·Ð°ÑÐ¸ÑÑ Ð´Ð»Ñ Ð¾ÑÐ²Ð¾Ð´Ð° Ð¿Ð¾Ð²ÐµÑÑÐ½Ð¾ÑÑÐ½ÑÑ ÑÑÐ¾ÑÐ½ÑÑ Ð²Ð¾Ð´ Ð¸ Ð¿ÑÐµÐ´Ð¾ÑÐ²ÑÐ°ÑÐµÐ½Ð¸Ñ Ð¿Ð¾Ð´ÑÐ¾Ð¿Ð»ÐµÐ½Ð¸Ñ ÑÐµÑÑÐ¸ÑÐ¾ÑÐ¸Ð¹. ÐÐ¾ Ð²ÑÐ¾ÑÐ¾Ð¹ ÑÐ°ÑÑÐ¸ Ð¿ÑÐ¾ÐµÐºÑÐ° ÑÐ°Ð·ÑÐ°Ð±Ð°ÑÑÐ²Ð°ÐµÑÑÑ ÑÐ°Ð·Ð´ÐµÐ» Ð°ÑÑÐ¸ÑÐµÐºÑÑÑÐ½ÑÑ ÑÐµÑÐµÐ½Ð¸Ð¹ Ð·Ð´Ð°Ð½Ð¸Ñ Ð¿Ð¾Ð¶Ð°ÑÐ½Ð¾Ð³Ð¾ Ð´ÐµÐ¿Ð¾, Ð²ÑÐ¾Ð´ÑÑÐµÐ³Ð¾ Ð² ÑÐ¾ÑÑÐ°Ð² Ð½Ð°ÑÐµÐ»ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ½ÐºÑÐ°. Ð¢Ð°ÐºÐ¶Ðµ Ð¾Ð³Ð¾Ð²Ð°ÑÐ¸Ð²Ð°ÑÑÑÑ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ñ ÑÑÐ½Ð´Ð°Ð¼ÐµÐ½ÑÐ¾Ð² Ð¸ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð²Ð½ÑÐµ ÑÐµÑÐµÐ½Ð¸Ñ ÐºÐ°ÑÐºÐ°ÑÐ° Ð·Ð´Ð°Ð½Ð¸Ñ. Ð Ð°Ð±Ð¾ÑÐ° ÑÐ¾Ð´ÐµÑÐ¶Ð¸Ñ 27 Ð»Ð¸ÑÑÐ¾Ð² Ð¿Ð¾ÑÑÐ½Ð¸ÑÐµÐ»ÑÐ½Ð¾Ð¹ Ð·Ð°Ð¿Ð¸ÑÐºÐ¸ Ð¸ 26 Ð»Ð¸ÑÑÐ¾Ð² Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ°ÑÑÐ¸.
Dynamically generated resonances
Creators: name: Oset, E.
name: Ramos, A.
name: Sarkar, S.
name: Sun, Bao Xi
name: Vacas, M. J. Vicente
name: Gonzalez, P.
name: Vijande, J.
name: Jido, D.
name: Sekihara, T.
name: Torres, A. Martinez
name: Khemchandani, K.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this talk I report on recent work related to the dynamical generation of baryonic resonances, some made up from pseudoscalar meson-baryon, others from vector meson-baryon and a third type from two meson-one baryon systems. We can establish a correspondence with known baryonic resonances, reinforcing conclusions previously drawn and bringing new light on the nature of some baryonic resonances of higher mass.
description: Talk given at the Workshop on physics of the excited nucleon-NSTAR 2009, Beijing, april 2009
Matrigel plug assay: evaluation of the angiogenic response by reverse transcription-quantitative PCR
Creators: name: Coltrini, Daniela
name: Di Salle, Emanuela
name: Ronca, Roberto
name: Belleri, Mirella
name: Testini, Chiara
name: Presta, Marco
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014

description: The subcutaneous Matrigel plug assay in mice is a method of choice for the in vivo evaluation of pro- and anti-angiogenic molecules. However, quantification of the angiogenic response in the plug remains a problematic task. Here we report a simple, rapid, unbiased and reverse transcription-quantitative PCR (RT-qPCR) method to investigate the angiogenic process occurring in the Matrigel plug in response to fibroblast growth factor-2 (FGF2). To this purpose, a fixed amount of human cells were added to harvested plugs at the end of the in vivo experimentation as an external cell tracer. Then, mRNA levels of the pan endothelial cell markers murine CD31 and vascular endothelial-cadherin were measured by species-specific RT-qPCR analysis of the total RNA and data were normalized for human GAPDH or β-actin mRNA levels. RT-qPCR was used also to measure the levels of expression in the plug of various angiogenesis/inflammationrelated genes. The procedure allows the simultaneous, quantitative evaluation of the newly-formed endothelium and of non endothelial/inflammatory components of the cellular infiltrate in the Matrigel implant, as well as the expression of genes involved in the modulation of the angiogenesis process. Also, the method consents the quantitative assessment of the effect of local or systemic administration of anti-angiogenic compounds on the neovascular response triggered by FGF2.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
Posphodiesterase 5 regulates the beating rate in murine neonatal cardiomyocytes
Creators: name: Cornacchione, Marisa
name: Barbagallo, Federica
name: Pellegrini, Manuela
name: Zevini, Alessandra
name: Torre, Maria
name: Isidori, Andrea M.
name: Naro, Fabio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2014

description: Heart rate is fi nely regulated by the sympathetic nervous system through beta adrenoreceptors (βARs) signaling. β-ARs stimulation induces cAMP/cGMP synthesis whereas phosphodiesterases (PDE) catalyze the hydrolysis of the cyclic nucleotides, however their precise interaction is not well defi ned (1, 2). The experimental model used to investigate the role of PDE5 inhibition on the heart function are the spontaneously beating cardiac myocytes from neonatal mice. Preliminary experiments were performed to determine whether neonatal cardiomyocyte cultures show the same PDEs expression pattern of adult mice hearts. We analyzed through RT-PCR and WB experiments the mRNA and protein levels of PDE1C, PDE2, PDE3A, PDE4 and PDE5 and we observed that are expressed both in hearts and in cultured neonatal cardiomyocytes. These data suggest that the cardiomyocyte is a suitable model to investigate the PDEs role in cardiac function. Experiments performed to evaluate the contraction rate stimulated by β-AR signaling activation show: that PDE5 is a positive modulator through hydrolysis of cGMP, and the inhibition of PDE5 causes a positive chronotropic eff ects reduction by the PDE2 activation through the increase of cGMP level. Notably, the use of PDE2 knockout mice reverts the negative chronotropic eff ects obtained by PDE5 inhibition. Finally, we observed that PDE5 selectively impacts heart rate interfering with β2AR signaling in neonatal cardiac myocytes, with little or no eff ect on β1AR signaling. These data show a novel role of PDE5 on the sympathetic regulation of cardiac beating and highlight the mechanicistic pathways of the long term eff ect of PDE5 inhibition in cardiac hypertrophy.
description: Italian Journal of Anatomy and Embryology, Vol 118, No 2 (Supplement) 2013
Harrison-Z'eldovich primordial spectrum is consistent with observations
Creators: name: Pandolfi, S.
name: Cooray, A.
name: Giusarma, E.
name: Kolb, E. W.
name: Melchiorri, A.
name: Mena, O.
name: Serra, P.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Inflation predicts primordial scalar perturbations with a nearly scale-invariant spectrum and a spectral index approximately unity (the Harrison--Zel'dovich (HZ) spectrum). The first important step for inflationary cosmology is to check the consistency of the HZ primordial spectrum with current observations. Recent analyses have claimed that a HZ primordial spectrum is excluded at more than 99% c.l.. Here we show that the HZ spectrum is only marginally disfavored if one considers a more general reionization scenario. Data from the Planck mission will settle the issue.
description: 4 Pages, 2 Figures
Hepatic progenitor cells as a source of adipokines and glucagon-like peptide-1 in pediatric nonalcoholic fatty liver disease
Creators: name: Carpino, Guido
name: Nobili, Valerio
name: Onori, Paolo
name: Alisi, Anna
name: Franchitto, Antonio
name: De Vito, Rita
name: Mancinelli, Romina
name: Alpini, Gianfranco
name: Alvaro, Domenico
name: Gaudio, Eugenio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: adiponectin; resistin; NASH; stem; progenitor

description: Background & aims. nonalcoholic fatty liver disease (NAFLD) is one of the most important causes of liver-related morbidity and mortality in children. NAFLD includes a spectrum of diseases ranging from simple fatty liver to nonalcoholic steatohepatitis (NASH)1. NASH development is characterized by intricate interactions between resident and recruited cells2. The aim of our study was to evaluate the involvement of Hepatic Progenitor Cells (HPCs) in pediatric NAFLD. Methods. 20 untreated, consecutive children and adolescents with biopsy-proven NAFLD (12 NASH, 8 NO-NASH) were studied by immunohistochemistry/fluorescence. HPCs and intermediate hepatocytes were counted and correlated with steatosis, inflammation, hepatocyte ballooning, fibrosis and the NAFLD activity score (NAS). Finally, the expression of adipokines (adiponectin, resistin, GLP-1) in liver cells was assessed. Results. HPC compartment was markedly expanded in pNAFLD and especially in childrens with NASH and this was independently associated with the degree of fibrosis. NASH livers were also characterized by the appearance of intermediate hepatocytes. Adiponectin expression in HPCs of NAFLD patients appears to be down-regulated with respect to the normal liver and this was correlated with lobular inflammation and steatosis. Resistin expression increases in pNAFLD in relation with the expansion of HPCs pool and with the degree of fibrosis. GLP-1 was overexpressed in HPCs of pNAFLD patients in relation with the degree of steatosis and NAS. Conclusions. HPCs activation takes part of liver response to oxidative stress in pediatric NAFLD and is correlated with the setting of fibrosis and the progression towards NASH. Adiponectin, resistin and GLP-1 become available to liver resident cells not only through the bloodstream but, possibly, through local production by paracrine mechanisms. The intra-hepatic expression of these proteins is strongly associated with the severity of pediatric NAFLD and may have relevant implications both in diagnosis and therapy. 1. Alisi A et al. J Pediatr 2009;155:469-74 2. Gaudio E et al. Dig Liver Dis 2009;41:455-62
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
title: Ð¢ÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¿ÑÐ¾ÑÐµÑÑ Ð¸Ð·Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð´ÐµÑÐ°Ð»Ð¸ "Ð¦Ð¸Ð»Ð¸Ð½Ð´Ñ"
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÑÑÐ°ÑÐ¾Ð², ÐÐ»ÐµÐºÑÐ°Ð½Ð´Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð¿ÑÐ¾ÑÐµÑÑ
Ð´Ð¾ÐºÑÐ¼ÐµÐ½ÑÐ°ÑÐ¸Ñ
ÑÐ¸Ð¿ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²Ð°
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ÑÐµÐ¶Ð¸Ð¼Ñ ÑÐµÐ·Ð°Ð½Ð¸Ñ
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ÑÐµÐ¶ÑÑÐ¸Ðµ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÑ
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description: Ð Ð¿ÐµÑÐ²Ð¾Ð¼ ÑÐ°Ð·Ð´ÐµÐ»Ðµ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¿ÑÐ¾ÑÐµÑÑ Ð´Ð»Ñ Ð´ÐµÑÐ°Ð»Ð¸ "Ð¦Ð¸Ð»Ð¸Ð½Ð´Ñ" Ð²Ð¼ÐµÑÑÐµ Ñ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ¾Ð¼ Ð´Ð¾ÐºÑÐ¼ÐµÐ½ÑÐ°ÑÐ¸Ð¸, Ð²ÐºÐ»ÑÑÐ°ÑÑÐ¸Ð¼ Ð² ÑÐµÐ±Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÑÑ Ð¸ Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÑÑ ÑÐ°ÑÑÐ¸. ÐÐ¾ Ð²ÑÐµÐ¼Ñ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ°ÑÑÐ¸ Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÑÐ½ Ð¿Ð¾Ð´ÑÐ¾Ð±Ð½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¸ÑÑÐ¾Ð´Ð½ÑÑ Ð´Ð°Ð½Ð½ÑÑ, Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÑÐ½ ÑÐ¸Ð¿ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²Ð° Ð¸ Ð²ÑÐ±ÑÐ°Ð½ Ð¼ÐµÑÐ¾Ð´ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð¸Ñ Ð¸ÑÑÐ¾Ð´Ð½Ð¾Ð¹ Ð·Ð°Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸. Ð¡ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð° ÑÑÑÑÐºÑÑÑÐ° Ð¾Ð¿ÐµÑÐ°ÑÐ¸Ð¹ Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð° Ð¿Ð¾ÑÐ»ÐµÐ´Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾ÑÑÑ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ñ Ð¿ÐµÑÐµÑÐ¾Ð´Ð¾Ð², ÑÐ°ÑÑÑÐ¸ÑÐ°Ð½Ñ ÑÐµÐ¶Ð¸Ð¼Ñ ÑÐµÐ·Ð°Ð½Ð¸Ñ Ð¸ Ð½Ð¾ÑÐ¼Ñ Ð²ÑÐµÐ¼ÐµÐ½Ð¸. ÐÐ¾ Ð²ÑÐ¾ÑÐ¾Ð¼ ÑÐ°Ð·Ð´ÐµÐ»Ðµ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ° ÑÐ¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¾ Ð½ÐµÑÐºÐ¾Ð»ÑÐºÐ¾ ÑÐµÐ¶ÑÑÐ¸Ñ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ¾Ð² Ð´Ð»Ñ Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð·Ð°Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Ð½Ð° Ð¾ÑÐ´ÐµÐ»ÑÐ½ÑÑ Ð¾Ð¿ÐµÑÐ°ÑÐ¸ÑÑ: ÑÐ°ÑÐ¾Ð½Ð½ÑÐ¹ Ð´Ð¸ÑÐºÐ¾Ð²ÑÐ¹ ÑÐµÐ·ÐµÑ, ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑ Ð¼ÐµÑÑÐ¸ÐºÐ¾Ð², Ð¸ ÑÐµÑÐ²ÑÑÐ½Ð°Ñ ÑÑÐµÐ·Ð° Ð´Ð»Ñ Ð½Ð°ÑÐµÐ·Ð°Ð½Ð¸Ñ ÑÐ¸Ð»Ð¸Ð½Ð´ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð·ÑÐ±ÑÐ°ÑÑÑ ÐºÐ¾Ð»ÑÑ. Ð ÑÑÐµÑÑÐµÐ¼ ÑÐ°Ð·Ð´ÐµÐ»Ðµ Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ð° Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ñ Ð¾Ð´Ð½Ð¾Ð¹ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð¾Ð¿ÐµÑÐ°ÑÐ¸Ð¸. ÐÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÑÐ½ Ð²ÑÐ±Ð¾Ñ Ð¸ Ð°Ð½Ð°Ð»Ð¸Ð· Ð·Ð°Ð³ÑÑÐ·Ð¾ÑÐ½Ð¾Ð³Ð¾ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð°, Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð° ÐºÐ¾Ð¼Ð¿Ð¾Ð½Ð¾Ð²Ð¾ÑÐ½Ð°Ñ ÑÑÐµÐ¼Ð° Ð²Ð¼ÐµÑÑÐµ Ñ ÑÐ¸ÐºÐ»Ð¾Ð³ÑÐ°Ð¼Ð¼Ð¾Ð¹. Ð ÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð¼ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ñ ÑÑÐ°Ð» ÑÐµÑÑÑÐ¶ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÑÑÑÐµÐ³Ð¾ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð°.
Human Body Posturizer (H.B.P.): new orthosis for improving postural dynamics
Creators: name: Colaiacomo, Barbara
name: Mantini, Simone
name: Ciccarelli, Antonello
name: Ripani, Maurizio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: posture; Human Body Posturizer; spine; orthosis; geometric morphometry

description: Introduction. Posture is the result of many complex processes involving the entire body in relationship with different environmental changes (Penha P.J.,2005). Interaction between the different anatomical districts occurs at different levels and it is influenced by different initial conditions. Alterations in imbalances and associated diseases produce a structural and physiologic reorganization of the anatomical structures to improve postural dynamics (Kasim et al., 2010). Generally, these modifications can be divided into para-mophisms and dis-morphisms of the spine. Currently postural diseases are treated by passive (brace and orthosis) and active (gymnastic) methods according with the severity of imbalance (LeBauer et al., 2008; Ugwonali et al., 2004). Purpose of this study is to validate a new type of orthosis named Human Body Posturizer (H.B.P). It is a modular flexible structure composed of different modules which act on the cervical, thoracic and lumbar traits of the back, and an inferior module which acts on the inferior limbs. Materials and methods. The present study considers a sample of 20 male subjects with age spanning from 19 to 35 years (mean age 23,4 ± 4,3). Subjects underwent 4 weeks of H.B.P. treatment consisting of 30 minutes, two times for week. The sample was analyzed by using the Surfacer System (Diagnostic Support), which permits to capture the external geometry of the back. Each subject was sampled before and after the treatment and differences between pre and post treatment were analyzed trough geometric morphometric approach (Slice 2000). Results. The results of this study showed a reorganization of the bilateral structures of the back after treatment. In particular an increased degree of symmetry was observed both in trunk and lumbar regions of the back. Conclusions. The preliminary results of the present study suggest that the HBP, acts on the spatial organization of the back, rectifying the position of the anatomical components associated to the early postural diseases. Nevertheless these results should be considered as preliminary and need of further researches.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
Spreading pressure bumps in gas-dust discs can stall planet migration via planet-vortex interactions
Creators: name: Chametla, R. O.
name: Chrenko, O.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We investigate the gravitational interaction between low- to intermediate-mass planets ($M_p \in[0.06-210]\,M_{\oplus}$) and two previously formed pressure bumps in a gas-dust protoplanetary disc. We explore how the disc structure changes due to planet-induced perturbations and also how the appearance of vortices affects planet migration. We use multifluid 2D hydrodynamical simulations and the dust is treated in the pressureless-fluid approximation, assuming a single grain size of $5\,μ{\mathrm{m}}$. The initial surface density profiles containing two bumps are motivated by recent observations of the protoplanetary disc HD163296. When planets are allowed to migrate, either a single planet from the outer pressure maximum or two planets from each pressure maximum, the initial pressure bumps quickly spread and merge into a single bump which is radially wide and has a very low amplitude. The redistribution of the disc material is accompanied by the Rossby Wave Instability (RWI) and an appearance of mini-vortices that merge in a short period of time to form a large vortex. The large vortex induces perturbations with a spiral wave pattern that propagate away from the vortex as density waves. We found that these vortex-induced spiral waves strongly interact with the spiral waves generated by the planet and we called this mechanism the "\textit{Faraway Interaction}". It facilitates much slower and/or stagnant migration of the planets and it excites their orbital eccentricities in some cases. Our study provides a new explanation for how rocky planets can come to have a slow migration in protoplanetary discs where vortex formation occurs.
description: 14 pages, 14 figures, accepted for publication in MNRAS
title: Ð¡Ð¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð±ÑÑ Ð³Ð°Ð»ÑÐµÑÑÐºÐ¾Ð³Ð¾ ÑÑÐµÑÐ° Ð¸ Ð½Ð°Ð»Ð¾Ð³Ð¾Ð¾Ð±Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾-ÑÐºÑÐ¿ÐµÐ´Ð¸ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ ÐÐÐ "Ð¤Ð¾ÑÐ²Ð°ÑÐ´ Ð¢ÑÐ°Ð½Ñ"
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐµÐ½ÐµÐ´Ð¸ÐºÑÐ¾Ð²Ð°, ÐÐ°Ð»Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: Ð±ÑÑ Ð³Ð°Ð»ÑÐµÑÑÐºÐ¸Ð¹ ÑÑÐµÑ
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ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½ÑÐµ ÑÐºÑÐ¿ÐµÐ´Ð¸ÑÐ¸Ð¸
accounting
taxation
transport expedition

description: Ð Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ´ÐµÐ»Ð°Ð½ Ð¾Ð±Ð·Ð¾Ñ Ð½Ð¾ÑÐ¼Ð°ÑÐ¸Ð²Ð½Ð¾Ð¹ Ð¸ Ð·Ð°ÐºÐ¾Ð½Ð¾Ð´Ð°ÑÐµÐ»ÑÐ½Ð¾Ð¹ Ð±Ð°Ð·Ñ Ð¿Ð¾ Ð²Ð¾Ð¿ÑÐ¾ÑÐ°Ð¼ Ð±ÑÑÐ³Ð°Ð»ÑÐµÑÑÐºÐ¾Ð³Ð¾ ÑÑÐµÑÐ° Ð¸ Ð½Ð°Ð»Ð¾Ð³Ð¾Ð¾Ð±Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð´Ð¾Ð³Ð¾Ð²Ð¾ÑÐ¾Ð² ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾Ð¹ ÑÐºÑÐ¿ÐµÐ´Ð¸ÑÐ¸Ð¸. ÐÑÐ¸Ð²ÐµÐ´ÐµÐ½Ð° Ð¾Ð±ÑÐ°Ñ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ° Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ ÐÐÐ "Ð¤Ð¾ÑÐ²Ð°ÑÐ´ Ð¢ÑÐ°Ð½Ñ" Ð¸ ÑÐ°ÑÑÐµÑ ÑÐµÑÐ½Ð¸ÐºÐ¾-ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÐµÐ¹. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð´Ð¾Ð³Ð¾Ð²Ð¾ÑÐ¾Ð² ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾Ð¹ ÑÐºÑÐ¿ÐµÐ´Ð¸ÑÐ¸Ð¸ Ð² Ð¸ÑÑÐ»ÐµÐ´ÑÐµÐ¼Ð¾Ð¹ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸.
description: In undergraduate work, a review of regulatory and legal acts on issues of accounting and taxation, contracts of transport expedition. The General characteristics of the organization OOO "Forvard TRANS" and calculation of technical and economic indicators. The analysis of the contracts of transport expedition in the studied organization.
A Self-Determination Theory perspective on student teachers´ basic needs, motivation, and study quality: A pre-registered qualitative study
Creators: name: Weinstein, Netta
name: Jeno, Lucas Matias
name: Roness, Dag
name: Nylehn, Jorun
name: Zeljana Pavlovic
name: Levesque-Bristol, Chantal
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Higher Education
subject: Educational Psychology
subject: Social and Behavioral Sciences
subject: Social Psychology
subject: Psychology
subject: FOS: Psychology
subject: Education
subject: Motivation
subject: Thematic analysis
subject: Teacher education
subject: Self-Determination Theory

description: The primary aim of this study is to investigate the experiential qualities underpinning student teachers´ experiences with study quality in higher education. We will investigate this using a motivational perspective through the lens of Self-Determination Theory (SDT). According to SDT, humans have three basic psychological needs for autonomy (feeling volitional and choiceful), competence (feeling effective and mastery), and relatedness (feeling close and cared for by others) (Ryan and Deci, 2017). When these needs are satisfied, students´ motivation is characterized by self-endorsement, volition, and choice (i.e., autonomous motivation). In contrast, when these needs are thwarted, students’ motivation is more likely to be characterized by either external or internal pressures such as rewards, threats of punishment, guilt, or pride (i.e., controlled motivation). Studies suggest that satisfaction of the basic psychological needs and autonomous motivation are essential for optimal student functioning. One area that has been less studies is study quality. According to Hovdhaugen et al. (2016), there are different understandings of quality in higher education. A more recent understanding concerns input (e.g., admission quality or teacher-student ratio), process (e.g., how teaching is conducted), and output (e.g., dropout, relevant work after degree). According to the Norwegian Study inspection regulation there are certain requirements for study quality in the study programs in higher education in Norway. The study programs need, amongst other, to be relevant for the work life, be within 1500-1800 hours workload per student, the content of-, construction-, infrastructure-, and the teaching/learning/assessment in the study program should be adapted to the learning outcomes for study program, and students should be allowed to take an active role in the learning process. This current study investigates study quality as operationalized within the Study inspection regulation from the lens of SDT. To understand how student experience study quality, we conduct focus group interviews using thematic analysis with a deductive approach.
Additional file 1 of Estimating the potential impact of the Australian government’s reformulation targets on household sugar purchases
Creators: name: Coyle, Daisy H.
name: Shahid, Maria
name: Dunford, Elizabeth K.
name: Louie, Jimmy Chun Yu
name: Trieu, Kathy
name: Marklund, Matti
name: Neal, Bruce
name: Wu, Jason H. Y.
Publisher: name: figshare
Year: 2021
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1: Supplementary Table 1. List of the Australian sugar reformulation targets [1]. Supplementary Table 2. List of the food categories included in the UK sugar reduction targets [2]. Supplementary Figure 1. Participant flow diagram. Supplementary Table 3. Household characteristics of the NielsenIQ Homescan Consumer panel in 2018. Supplementary Table 4. Modelled impact of the UK sugar reduction targets on changes to sugar purchases (g/d per capita), by income level
Directed transport as a mechanism for protein folding in vivo
Creators: name: Gonzalez-Candela, Ernesto
name: Romero-Rochin, Victor
Publisher: name: arXiv
Year: 2009
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We propose a model for protein folding in vivo based on a Brownian-ratchet mechanism in the multidimensional energy landscape space. The device is able to produce directed transport taking advantage of the assumed intrinsic asymmetric properties of the proteins and employing the consumption of energy provided by an external source. Through such a directed transport phenomenon, the polypeptide finds the native state starting from any initial state in the energy landscape with great efficacy and robustness, even in the presence of different type of obstacles. This model solves Levinthal's paradox without requiring biased transition probabilities but at the expense of opening the system to an external field.
description: 16 pages, 7 figures
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÑÐ¸Ð¼ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿ÐµÑÑÐ¾Ð½Ð°Ð»Ð° Ð½Ð° Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ð¸
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð¥ÑÐ¸ÑÑÐ¾ÑÐ¾ÑÐ¾Ð²Ð°, ÐÑÐ´Ð¼Ð¸Ð»Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: ÑÑÐ¸Ð¼ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
Ð¿ÐµÑÑÐ¾Ð½Ð°Ð»
Ð¼Ð¾ÑÐ¸Ð²Ð°ÑÐ¸Ñ
stimulation
personnel
motivation

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