cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Protostellar Disk Evolution Over Million-Year Timescales with a Prescription for Magnetized Turbulence
Creators: name: Landry, Russell
name: Dodson-Robinson, Sarah E.
name: Turner, Neal J.
name: Abram, Greg
Publisher: name: arXiv
Year: 2013
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Magnetorotational instability (MRI) is the most promising mechanism behind accretion in low-mass protostellar disks. Here we present the first analysis of the global structure and evolution of non-ideal MRI-driven T-Tauri disks on million-year timescales. We accomplish this in a 1+1D simulation by calculating magnetic diffusivities and utilizing turbulence activity criteria to determine thermal structure and accretion rate without resorting to a 3-D magnetohydrodynamical (MHD) simulation. Our major findings are as follows. First, even for modest surface densities of just a few times the minimum-mass solar nebula, the dead zone encompasses the giant planet-forming region, preserving any compositional gradients. Second, the surface density of the active layer is nearly constant in time at roughly 10 g/cm2, which we use to derive a simple prescription for viscous heating in MRI-active disks for those who wish to avoid detailed MHD computations. Furthermore, unlike a standard disk with constant-alpha viscosity, the disk midplane does not cool off over time, though the surface cools as the star evolves along the Hayashi track. The ice line is firmly in the terrestrial planet-forming region throughout disk evolution and can move either inward or outward with time, depending on whether pileups form near the star. Finally, steady-state mass transport is a poor description of flow through an MRI-active disk. We caution that MRI activity is sensitive to many parameters, including stellar X-ray flux, grain size, gas/small grain mass ratio and magnetic field strength, and we have not performed an exhaustive parameter study here.
description: Accepted for publication in Astrophysical Journal. 19 pages, including 8 figures
Non-Markovian effects at the Fermi-edge singularity in quantum dots
Creators: name: Roszak, Katarzyna
name: Novotný, Tomáš
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study electronic transport through a quantum dot in the Fermi-edge singularity regime, placing emphasis on its non-Markovian attributes. These are quantified by the behavior of current noise as well as trace-distance-based measure of non-Markovianity and found to be pronounced at low temperatures where the interplay of many-electron correlations and quantum coherence present in the system leads to significant quantum memory effects and non-Markovian dynamics.
description: 8 pages, 8 figures; proceedings of FQMT'11 conference (Prague, 2011)
Computational, biochemical and ex vivo evaluation of xanthine derivatives against phosphodiesterases to enhance the sperm motility
Creators: name: Satish, Mutyala
name: Sandhya, Kumari
name: Nitin, Kulhar
name: Kiran, Ninjoor Yashas
name: Aleena, Babu
name: Kumar, Adiga Satish
name: Guruprasad, Kalthur
name: Rajakumara, Eerappa
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer

description: Enhancing sperm motility in vitro has immensely benefited assisted conception methods. Phosphodiesterases (PDE) break the second messenger cAMP, and therefore, inhibition of their catalytic activity enhances the sperm motility through maintaining cAMP homeostasis in sperm. In view of identifying the molecules that could inhibit PDE functioning in spermatozoa, we aimed to evaluate the phosphodiesterase inhibitors (PDEI) - xanthine derivatives - acefylline, dyphylline and proxyphylline to repurpose them for assisted reproductive technology. These are available in the market as pharmaceutical agents to treat mainly respiratory system diseases. Based on the structure guided in silico studies, we predicted that these molecules bind to the cAMP binding catalytic pocket of PDE enzymes, and further molecular dynamics simulation analysis indicated that these molecules form the stable complexes. Isothermal titration calorimetry studies revealed that acefylline has better affinity towards PDE4A, PDE4D and PDE10A, when compared to dyphylline and proxyphylline. In addition, ex vivo studies corroborated in vitro binding studies that acefylline has much superior sperm motility enhancement property on human ejaculated spermatozoa and mouse testicular spermatozoa compared to dyphylline and proxyphylline. Communicated by Ramaswamy H. Sarma
Argumentation strategies in an online male separatist community
Creators: name: Aiston, Jessica
Publisher: name: Lancaster University
Year: 2023

description: This thesis explores the legitimation of ‘male separatist’ ideology in an online community known as ‘Men Going Their Own Way’ (MGTOW). I take a discourse-historical approach to critical discourse studies (Reisigl and Wodak, 2016), as adapted for social media data (Unger et al., 2021), in order to examine the argumentation strategies and topoi used by members of this community to persuade others to abstain from relationships with women and reject feminism. The dataset comprises fifty threads totalling 46,000 words from the major MGTOW community hosted on Reddit. As well as contributing to a growing body of research on the manosphere, this thesis demonstrates how the DHA and topoi can be applied to social media discussion forums, where argumentation may be collaborative or expressed multimodally. Findings indicate that women were constructed as a homogenous group, meaning men must separate from all women. Arguments in favour of separatism typically relied on a topos of freedom in order to suggest that separating from women will increase men’s independence. This was often combined with a topos of finance, where increased personal freedoms included the freedom to decide how one’s money is spent and freedom from financial obligations to others. Relatedly, relationships were framed in economic terms and as a series of financial transactions, discussed in terms of the costs (to men) and benefits (to women). Furthermore, arguments against marriage used the topos of threat to construct women as a danger to men’s physical and emotional wellbeing, for example by arguing that married men risk having their lives ‘ruined’ by false claims of abuse. Arguments in opposition to feminism employed the topos of justice in order to highlight the purported the unequal treatment of men by feminists. Equality appeared to be equivalent to sameness and treating different genders in exactly the same manner, enabling commenters to delegitimise feminist activism targeting women as evidence of male oppression.
Becoming an Adult through Adversity: Young People’s Stories of the Transition to Adulthood
Creators: name: Roswess-Bruce, Natalie
Publisher: name: University of East London
Year: 2022

description: Background The transition to adulthood is positioned as a crucial developmental process within the human lifespan (Brown, 2018), that research suggests has become increasingly more difficult and prolonged for the population of British youth, consequent to shifts in their social and economic context (Roberts & Lawrence, 2017). These trends are more prominent for racially subjugated youth, with long term psychosocial implications for clinical psychology practice. (Mac an Ghaill & Haywood, 2005; Malek, 2011; Street et al., 2005). Despite this there is little clarity around becoming an adult from the perspectives of British Black and minority ethnic youth. Aims This research aims to explore the stories British Black and minority ethnic youth tell of becoming an adult in the United Kingdom (UK), and how hardship and culture feature within them. Methodology Taking a critical realist epistemological position, this research utilised unstructured interviews, narrative artefacts and systematic narrative analysis to explore how four British Black and minority ethnic youths’, aged 20-26yrs, storied their transition to adulthood in the UK. Findings Overall, the findings state that the narratives British Black and ethnic minority youth use to story becoming an adult, are shaped by their historical, social, economic and cultural context. Conclusions This research provides an important insight into the intersection between hardships, culture, identity and the transition to adulthood, amongst youth from subjugated British communities. While these findings do not claim to be generalisable, they support research that states young people from racialised backgrounds experience the psychosocial difficulties that impact all young people, plus additional issues specific to their culture, race and ethnicity (Malek, 2011; Street et al., 2005). Consequently, elevating British Black, and minority ethnic youth’s stories of becoming adults within the context of their broader inequalities, is essential for providing adequate evidence-based care and support that meets their intersectional needs.
CO J=1-0 and J=2-1 Line Observations of the Molecular Cloud - Blocked Supernova Remnant 3C434.1
Creators: name: Jeong, Il-Gyo
name: Koo, Bon-Chul
name: Cho, Wan-Kee
name: Kramer, Carsten
name: Stutzki, Jürgen
name: Byun, Do-Young
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the results of CO emission line observations toward the semicircular Galactic supernova remnant (SNR) 3C434.1 (G94.0+1.0). We mapped an area covering the whole SNR in the 12CO J=1-0 emission line using the Seoul Radio Astronomy Observatory (SRAO) 6-m telescope, and found a large molecular cloud superposed on the faint western part of the SNR. The cloud was elongated along the north-south direction and showed a very good spatial correlation with the radio features of the SNR. We carried out 12CO J=2-1 line observations of this cloud using the Kölner Observatorium für Sub-Millimeter Astronomie (KOSMA) 3-m telescope and found a region in which the 12CO J=2-1 to J=1-0 ratio was high (~ 1.6). This higher excitation, together with the morphological relation, strongly suggested that the molecular cloud was interacting with the SNR. The systemic velocity of the molecular cloud (-13 km/s) gave a kinematic distance of 3.0 kpc to the SNR-molecular cloud system. We derived the physical parameters of the SNR based on this new distance. We examined the variation of the radio spectral index over the remnant and found that it was flatter in the western part, wherein the SNR was interacting with the molecular cloud. We therefore propose that 3C434.1 is the remnant of a supernova explosion that occurred just outside the boundary of a relatively thin, sheetlike molecular cloud. We present a hydrodynamic model showing that its asymmetric radio morphology can result from its interaction with this blocking molecular cloud.
description: 13 pages, 12 figures (some low resolution), 1 table, accepted for publication in the Astrophysical Journal
Workshop at the Dutch Open Science Festival 2022 - Getting Started in Citizen Science with the Principles & the Quality Matrix
Creators: name: Gold, Margaret
Publisher: name: Zenodo
Year: 2022
Subjects: Citizen Science

description: Citizen Science methods and approaches are becoming increasingly well recognised as an important means to bring science and society together in closer collaboration - they are embedded in the formally adopted UNESCO Recommendation on Open Science, described and supported in the recently ratified new legal instruments within the Aarhus convention, are emphasised throughout the Horizon Europe funding programme, and form the third pillar of the National Programme Open Science in the Netherlands. However, for career researchers it is not always clear where to start. To address this, members of the community of Citizen Science practitioners in the Netherlands formed a Working Group that was supported by the Dutch National Programme Open Science (NPOS) to address questions such as - ‘Where do you start?’, ‘What are the pitfalls?’, ‘How do you set up effective communication between professional scientists and citizen scientists?’, ‘How do you guarantee the quality of the process and outcomes?’ , and ‘How can the collaboration become sustainable?’ In this interactive workshop, members of the Working Group will present the resource that they developed to answer these questions - the Citizen Science Quality Matrix - which builds on The 10 Principles for Citizen Science of the European Citizen Science Association (ECSA). The Matrix translates these principles into success factors that provide guidance when designing and assessing citizen science projects, with a focus on both scientific and societal quality.
title: Spectroscopic characterisation of electrochemical biosensor interfaces
Creators: name: Foreman, Pamela Louise
Publisher: name: University of Glasgow
Year: 1998
Subjects: subject: Biomedical engineering.

description: The work presented in this thesis investigates the composition of various glucose and glutamate biosensor interfaces using the novel combination of electrochemical and spectroscopic techniques. Initially glucose sensors were prepared by electro-entrapment of the enzyme glucose oxidase (GOx) within thin, non-conducting films of poly(phenylene diamine) (p(pd)). Their electrochemical responses to glucose over the range 0-100 mmol dm'
White-dwarf red-giant mergers, early-type R stars, J stars and lithium
Creators: name: Zhang, Xianfei
name: Jeffery, C. Simon
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Early-type R stars and J stars are a special type of carbon star, having enhanced nitrogen ($\rm [N/Fe]\approx 0.5$), lithium, a low \iso{12}{C}/\iso{13}{C} ratio ($<15$) and no s-element enhancements. The merger of a helium white dwarf with a red giant is regarded to be a possible model for the origin of early-type R stars, but the details of nucleosynthesis are not clear. In this paper we investigate three possible channels for helium white-dwarf + red-giant mergers, and find that, amongst the three, only a high-mass helium white dwarf subducted into a low core-mass red giant can make an early-type R star. Nucleosynthesis of elements carbon, nitrogen, oxygen and lithium correspond well with the observations. Furthermore, we find that the J stars may represent a short and luminous stage in the evolution of an early-R star.
description: 10 pages, 17 figures. Accepted for publication in MNRAS
Atomic and Molecular Databases« Open Science for better science and a sustainable world »
Creators: name: Dubernet, Marie-lise
Publisher: name: Zenodo
Year: 2022
Subjects: IAUGA 2022
Atoms
Molecules
FAIR
Open Science
Astrophysics

description: The building of on-line atomic and molecular databases for astrophysics and for other applications fields have started from the beginning of the internet. Those have encompassed different forms: private databases exposing their own data, databases providing collected data from the refereed literature, databases providing evaluated compilation, databases providing repositories for individuals to deposit their data and so on. Those were and are the replacement for literature compilations with the goal to provide a better data service to the users communities. That work involved not only scientific work on the data, but also the characterization of the data, which could be seen as the start of the “standardization” of metadata and of the relations between metadata, as it has recently been developed in different communities. This talk aims at providing an overview of the atomic and molecular databases ecosystem which is available to the astrophysical community. It will describe the issues linked to format and data descriptions, to data exchanges and usage in astrophysical tools and codes. It will outline the various organizations of communities that provide access to atomic and molecular data and databases. Finally it will address long term sustainability issues linked to the scientific quality of the provided data and to their long term availability. Acknowledgement : This talk is fueled by the work performed by different actors over the years : databases, institutions such as the IAEA, the NIST, the IUPAC, infrastructures such as the VAMDC and more recently from the IAU B5 commission and its working groups, not forgetting the past history of other commissions linked to atomic and molecular data at the IAU. Acronyms : IAEA : International Atomic Energy Agency (iaea.org); NIST : National Institute of Standards and Technology (www.nist.gov); IUPAC : International Union of Pure and Applied Chemistry (iupac.org); VAMDC : Virtual Atomic and Molecular Data Centre (vamdc.org); B5 commission on Laboratory Astrophysics
Citizen Science within Open Science in the Netherlands - the Dutch National Programme Open Science (NPOS)
Creators: name: Gold, Margaret
Publisher: name: Zenodo
Year: 2022
Subjects: Citizen Science, Open Science

description: Presentation given by Margaret Gold at the Workshop held in Berlin on the 5th of October with the UNESCO Open Science signatory countries on HOW to progress citizen science into policy, to introduce the work within the Netherlands to establish an Open Science strategy towards 2030 that also addresses societal engagement and Citizen Science.
Copper(II) Schiff base complex derived from salen ligand: structural investigation, Hirshfeld surface analysis, anticancer and anti-SARS-CoV-2
Creators: name: Kumar, Sunil
name: Choudhary, Mukesh
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: This work deals with the synthesis and characterization of copper(II) complex [Cu(salen)(H2O)](1) of salen-type Schiff base ligand derived from the condensation of 5-bromo-2-hydroxy-3-methoxybenzaldehyde and ethylenediamine in EtOH. This complex was characterized by different spectroscopic and physicochemical methods. Single crystal X-ray crystallography study revealed that Cu(II) in complex (1) is five-coordinate and adopts a distorted square pyramidal geometry. A DFT calculation was employed to evaluate the optimized electronic structure, HOMO-LUMO, energy gap, and global parameters. A detailed structural and non-covalent interaction on the complex is investigated by single crystal structure analysis and computational approaches. The strength of the interaction and 3D topology of the crystal packing are visualized through an energy framework. Hirshfeld surface and 2D fingerprint plots have been explored in the crystal structure of the complex. The anticancer properties of copper(II) complex was studied against the selected cancerous cell lines of breast cancer, cervical cancer, colon cancer and hepatocellular carcinoma. Additionally, molecular docking and MD simulations was performed on the complex to predict the binding mode and interactions between the ligand and the main protease of the SARS-CoV-2 (PDB ID: 7CBT and 7D1M). The molecular docking calculations of the complex (1) with SARS-CoV-2 virus revealed the binding energy of –8.1 kcal/mol and –7.5 kcal/mol with an inhibition constant of 3.245 µM and 2.318 µM at inhibition binding site of receptor towards 7CBT and 7D1M main protease (Mpro), respectively. Besides this, molecular docking results (–7.6 kcal/mol, 3.196 µM) towards Escherichia coli PBP2 targets (PDB ID: 6G9S) was also studied. Communicated by Ramaswamy H. Sarma
Directional flow of solitons with asymmetric potential wells: Soliton diode
Creators: name: Asad-uz-zaman, M.
name: Khawaja, U. Al
Publisher: name: arXiv
Year: 2013
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We study the flow of bright solitons through two asymmetric potential wells. The scattering of a soliton by certain type of single potential wells, e.g., Gaussian or Rosen-Morse, is distinguished by a critical velocity above which solitons can transmit almost completely and below which solitons can reflect nearly perfectly. For two such wells in series with certain parameter combinations, we find that there is an appreciable velocity range for which solitons can propagate in one direction only. Our study shows that this directional propagation or diode behavior is due to a combined effect of the sharp transition in the transport coefficients at the critical velocity and a slight reduction in the center-of-mass speed of the soliton while it travels across a potential well.
description: 7 pages, 5 figures
title: How State-of-the-Art Makerspace Stations Contribute to Differences in Students’ Learning
title: A Mixed Methods Case Study of a Bilingual High School in Kuwait
titleType: Subtitle
Creators: name: Ali, Sayed
Publisher: name: Lancaster University
Year: 2023

description: Abstract As a means to nurture innovation and better prepare students for the world of tomorrow, schools are establishing makerspaces. Consequently, school makerspaces are gaining momentum in recent years. While makerspaces have been studied mostly in museums and libraries, little research has been conducted inside K–12 school makerspaces. The purpose of this exploratory mixed-methods case study was to examine the perceptions of teachers and students concerning learning in a standalone school makerspace, how the identifiable indicators of learners’ learning differ by station and to identify how such learning may assist students in being future-ready. Data collection is performed using mixed methods. The sample included 79 high school students and seven teachers who worked at five makerspace stations on different projects. Data were collected via online surveys, reflective journals, and observational notes. The tinkering learning dimensions framework, 21st-century skills framework, Gibbs’s reflective cycle, and the makerspace quadrant guided the design of data collection tools and discussion of the findings. This study contributes to the field by demonstrating how this school makerspace facilitated learning during a crisis through long-term projects using a novel blended projects model developed in this study. The cross-case analysis revealed that social and emotional engagement was the most visible learning dimension across all stations. The study results reveal that school makerspaces offer a context to develop 21st-century skills, becoming a hub for exploring many career pathways and providing real-life connections. The evidence also shows there to be a potential relationship between the makerspace stations and the learning dimensions. For example, while students at the technology station with no hands-on work had the lowest level of learning indicators, those at the 3D printing station had higher levels of learning indicators. The findings contribute to the ongoing scholarly conversations about the educational values of school makerspaces, and the discussion culminates in recommendations for practice and research.
DEPFET Pixels as a Vertex Detector for the Belle II Experiment
Creators: name: Schieck, Jochen
Publisher: name: arXiv
Year: 2013
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: Currently the heavy flavour factory KEKB located at the KEK accelerator centre in Tsukuba, Japan, is being upgraded to the Super KEKB factory, aiming for a substantially higher luminosity of 8x10^35 cm^-2 s^-1. This by a factor of 40 increased luminosity requires significant modifications of the Belle detector. The vertex detector needs to be redesigned and, besides a four-layer silicon strip detector, a pixel detector based on the DEPFET technology will be installed closest to the interaction point. The requirements for this pixel detector, the DEPFET technology and the current status of the pixel detector will be presented in this paper.
description: Proceedings for the VCI 2013 conference, 6 pages and 8 figures
Вступление
Creators: name: Кучера, Михайло
Publisher: name: figshare
Year: 2022
Subjects: Archaeology

description: Кучера, М. П. 1984. Вступление. В: Баран, В. Д. (отв. ред.). Древнерусские поселения Среднего Поднепровья (археологическая карта). Киев: Наукова думка, с. 3–5.
Поселения Среднего Поднепровья (Городища. Селища)
Creators: name: Кучера, Михайло
Publisher: name: figshare
Year: 2022
Subjects: Archaeology

description: Кучера, М. П. 1984. Поселения Среднего Поднепровья (Городища. Селища). В: Баран, В. Д. (отв. ред.). Древнерусские поселения Среднего Поднепровья (археологическая карта). Киев: Наукова думка, с. 6–27.
Virtually screened novel sulfathiazole derivatives as a potential drug candidate for methicillin-resistant Staphylococcus aureus and multidrug-resistant tuberculosis
Creators: name: Nagendran, Saraswathy
name: Balasubramaniyan, Sakthivel
name: Irfan, Navabshan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant tuberculosis (MDR-TB) is a leading cause of severe hospital and infection-related morbidity and mortality in the general population. There is a critical need for dynamic, powerful medication candidates to combat MRSA and MDR-TB infections in this specific setting. As a result, the current research focuses on the development of novel sulfathiazole derivative compounds that could be used as anti-MRSA and anti-MDR-TB agents. Virtual screening approaches were used to identify the potential lead sulfathiazole derivatives with the help of BIOVIA Discovery Studio 2017 software. In this in silico study, 10 novel sulfathiazole derivatives were virtually screened from 74 designed compounds. These 10 compounds had the best predictive docking scores in MRSA and MDR-TB receptors and were then put through a molecular dynamics simulation to explain protein stability, ligand characteristics and protein–ligand interactions. The Lipinski rule and ADMET prediction results also suggested that 11 compounds (mol-12, mol-22, mol-23, mol-28, mol-30, mol-32, mol-34, mol-35, mol-45 and mol-47) have strong drug similarity features. Our findings imply that the 10 novel sulfathiazole compounds studied could be viable new therapeutic leads for MRSA and MDR-TB. Communicated by Ramaswamy H. Sarma
Памятники правобережья и Левобережья Днепра. Междуречье Ствиги – Тетерева
Creators: name: Кучера, Михайло
name: Беляева, С.
name: Блажевич, Н.
name: Горишний, П.
name: Орлов, Р.
Publisher: name: figshare
Year: 2022
Subjects: Archaeology

description: Кучера, М. П., Беляева, С. А., Блажевич, Н. В., Горишний, П. А., Орлов, Р. С. 1984. Памятники правобережья и Левобережья Днепра. Междуречье Ствиги – Тетерева. В: Баран, В. Д. (отв. ред.). Древнерусские поселения Среднего Поднепровья (археологическая карта). Киев: Наукова думка, с. 28–38.
Laser-Machined Ultra-High-Q Microrod Resonators for Nonlinear Optics
Creators: name: Del'Haye, Pascal
name: Diddams, Scott A.
name: Papp, Scott B.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Optical whispering-gallery microresonators are useful tools in microphotonics, and nonlinear optics at very low threshold powers. Here, we present details about the fabrication of ultra-high-Q whispering-gallery-mode resonators made by CO2-laser lathe machining of fused-quartz rods. The resonators can be fabricated in less than one minute and the obtained optical quality factors exceed Q = 10^9. Demonstrated resonator diameters are in the range between 170 μm and 8 mm (free spectral ranges between 390 GHz and 8 GHz). Using these microresonators, a variety of optical nonlinearities are observed, including Raman scattering, Brillouin scattering and four-wave mixing.
description: 9 pages, 3 figures, to be published in APL
title: Herxheim near Landau – pottery of the LBK (Linear Pottery culture) outside the pit enclosure
Creators: name: Fetsch, Sandra
Publisher: name: University Library Heidelberg
Year: 2015

description: Die bandkeramischen Fundstellen der Gemarkung Herxheim außerhalb der Grubenanlage, von denen Lesefunde und Grabungsmaterial vorliegen, waren 2008 Gegenstand einer Magisterarbeit. Basierend auf der umfassenden Keramikbewertung erfolgten die relativchronologische Einordnung dieser Fundstellen und darauf aufbauend eine Modellierung der Siedlungsprozesse, die sich wahrscheinlich über die gesamte Dauer der Bandkeramik im linksrheinischen Gebiet erstreckten. Der Schwerpunkt der Analysen liegt auf einem 2001 ausgegrabenen zweiphasigen Hofplatz im unmittelbaren Umfeld der Grubenanlage. Dieser datiert, nach dem Motivrepertoire zu urteilen, an das Ende der Bandkeramik und war möglicherweise noch zu einem Zeitpunkt belegt, an welchem bislang, abgesehen von der Grubenanlage, in der Südpfalz keine Siedlungsaktivitäten mehr nachgewiesen sind.
description: Apart from the famous pit enclosure of Herxheim/Palatinate several early Neolithic settlement sites, known only from surveys and few excavations, have been identified in the general area. The associated pottery indicates that these settle ments persisted during the entire period of the western LBK culture (west of the river Rhine). Using correspondence analysis it was possible to develop a relative chronological order of the pottery allowing for further interpretations of settlement processes. A two-phase farmyard (Hofplatz) near the pit enclosure – excavated in 2001 – is described in detail. The repertoire of motifs from this site showed characteristics of the final LBK. It is possibly that this farmyard was occupied until the end of the final LBK, for which time in the southern Palatinate settlement activities had as yet only been documented at the pit enclosure of Herxheim
High Resolution Hypernuclear Spectroscopy at Jefferson Lab Hall A
Creators: name: Garibaldi, F.
name: Bydzovsky, P.
name: Cisbani, E.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The characteristics of the Jefferson Lab electron beam, together with those of the experimental equipment, offer a unique opportunity to study hypernuclear spectroscopy via electromagnetic induced reactions. Experiment 94-107 started a systematic study on 1p-shell targets, $^{12}C$, $^{9}Be$ and $^{16}O$. For $^{12}C$ for the first time measurable strength in the core-excited part of the spectrum between the ground state and the p state was shown in $^{12}_ΛB$ spectrum. A high-quality $^{16}_ΛN$ spectrum was produced for the first time with sub-MeV energy resolution. A very precise $Λ$ binding energy value for $^{16}_ΛN$, calibrated against the elementary $(e,e'K^+)$ reaction on hydrogen, has also been obtained. $^{9}_ΛLi$ spectrum shows some disagreement in strength for the second and third doublet with respect to the theory.
description: 6 pages, 5 figures, HYP2012 conference
title: Urnfields on the move: testing burial site-settlement relations in the eastern Netherlands (c. 1100-500 BC)
Creators: name: Beek, Roy Van
name: Louwen, Arjan
Publisher: name: University Library Heidelberg
Year: 2015

description: In allgemeinen Modellen zur Landschaftsorganisation der späten Bronzezeit und frühen Eisenzeit (1100-500 v. Chr.) werden die Urnengräberfelder als Kristallisationspunkte interpretiert, die Siedlungsverlegungen strukturierten und eine zentrale Lage in der Siedlungslandschaft besaßen. Die Urnenfelder blieben in der Landschaft statisch, die Siedlungen hingegen verhielten sich dynamisch. Allgemein wird angenommen, dass dieses einflussreiche Modell für größere Gebiete gültig ist, was jedoch noch nie überprüft wurde. In diesem Beitrag wird genau das für den östlichen Teil der Niederlande versucht. Die Analyse zeigt, dass die Beziehungen zwischen Urnenfeldern und Siedlungen viel variabler sind als bisher angenommen. Sowohl räumliche als auch chronologische Beobachtungen deuten an, dass die Landschaftsorganisation der späten Bronzezeit und frühen Eisenzeit weitaus abwechslungsreicher und dynamischer war, als es das allgemeine Modell uns glauben lässt. Zudem gibt es neue Ansichten zur Grundidee des Urnenfelderkonzepts. Urnenfelder werden im Allgemeinen als große, kollektive Gräberfelder betrachtet, die über viele Jahrhunderte benutzt werden und die aus einer großen Zahl von Urnengräbern und sie umgebenden Gräben bestehen. Viele Gräberfelder entsprechen aber nicht diesem traditionellen Bild – es scheint klar, dass die Uniformität der Urnenfelder bisher zu stark betont wurde.
description: In general models on Late Bronze Age and Early Iron Age (1100-500 BC) landscape organization, urnfields are interpreted as focal points that structured the movement of settlements across the landscape, and were located centrally within the settlement area. Urnfields were fixed, settlements shifted. These influential models are assumed to be valid for large areas. However, they have never been formally tested. In this paper an attempt is made to do so by using data from the eastern Netherlands. The analysis demonstrates that relations between urnfields and settlements are far more diverse than is generally assumed. Both spatial and chronological observations indicate that landscape organization during the Late Bronze Age and Early Iron Age was far more varied and dynamic than existing models make believe. Furthermore, new insights are gained with regard to the basic assumptions underneath the urnfield concept in itself. Urnfields are generally perceived as large, collective burial sites that were used for many centuries and consist of large numbers of urn burials with ditched structures. Many burial sites, however, do not conform to this traditional view at all, indicating that the uniformity of urnfields has been greatly exaggerated in the past.
Model predictive control and trajectory optimization of large vehicle-manipulators
Creators: name: Varga, Balint
name: Meier, Selina
name: Schwab, Stefan
name: Hohmann, Sören
Publisher: name: Institute of Electrical and Electronics Engineers (IEEE)
Year: 2019

description: In this paper, a model predictive control (MPC) is developed for on- and off-road mid-sized heavy duty vehicle-manipulator systems with a hydraulic working arm. The proposed concept for the control model is also new in the sense of working only within a local reference coordinate-system relative to the reference trajectory (so-called Fren´et-System). The control model only needs the errors to the reference trajectory. In contrast to other state-of-the-art approaches, there is no global localization method necessary. The control model is kept as simple as possible, to allow real-time motion prediction of the real system. For this reason, a kinematic model is used in the MPC which consists of a bicycle model and a planar robotic arm with two control variables. The dynamics of the overall system are considered as optimization constraints, assuming that the optimized system inputs and states are kinetically and dynamically feasible. Through this control method, the dual-trajectories are also optimized and they provide smooth motions for the overall system. The underlying control of the robotic arm is realized with a proportional–integral–derivative (PID) controller with feedback linearization and gravity compensation. The control algorithm is tested and validated in a MATLAB/Simulink simulation environment.
Deformed N=2 theories, generalized recursion relations and S-duality
Creators: name: Billo, Marco
name: Frau, Marialuisa
name: Gallot, Laurent
name: Lerda, Alberto
name: Pesando, Igor
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the non-perturbative properties of N=2 super conformal field theories in four dimensions using localization techniques. In particular we consider SU(2) gauge theories, deformed by a generic epsilon-background, with four fundamental flavors or with one adjoint hypermultiplet. In both cases we explicitly compute the first few instanton corrections to the partition function and the prepotential using Nekrasov's approach. These results allow to reconstruct exact expressions involving quasi-modular functions of the bare gauge coupling constant and to show that the prepotential terms satisfy a modular anomaly equation that takes the form of a recursion relation with an explicitly epsilon-dependent term. We then investigate the implications of this recursion relation on the modular properties of the effective theory and find that with a suitable redefinition of the prepotential and of the effective coupling it is possible, at least up to the third order in the deformation parameters, to cast the S-duality relations in the same form as they appear in the Seiberg-Witten solution of the undeformed theory.
description: 33 pages, no figures, LaTeX2e
Computational analysis of marine algal compounds for obesity management against pancreatic lipase
Creators: name: Prabhakar, Lavanya
name: John, Davis G. Dicky
name: Singh, Satya Ranjan
name: Murali, Ayaluru
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Obesity is considered a global crisis because of its increased risk factors triggered by lifestyle changes. The prevalence of this condition is increasing at an alarming rate, giving rise to development of novel drugs. Pancreatic lipase possesses higher efficacy in inhibiting this condition among the other drug targets. In this study, virtual screening of 126 plant-derived anti-obesity compounds and 1110 marine algal compounds from seaweed metabolite database were screened and targeted against pancreatic lipase and ranked based on their binding affinity values. A total of 530 compounds that possessed best docked scores of less than –6 kcal/mol were checked for Lipinski’s properties through Swiss ADME. Furthermore, these compounds were subjected to toxicity prediction using PROTOX II server. As much as 38 compounds were found to be non-toxic and were subjected to molecular docking analysis. Based on the binding energy, the following compounds RG012 (–10.15 kcal/mol), LIG42 (–9.7 kcal/mol), BC010 (–8.47 kcal/mol), RL073 (–8.2 kcal/mol), and LIG46 (–8.03 kcal/mol) were selected exhibiting higher binding affinity when compared to the standard drug (Orlistat) and hence these compounds were subjected to molecular dynamics simulation using GROMACS. BC010 complex revealed a stable interaction within the binding pocket and the binding free energy is –158.208 kJ/mol which is higher when compared to other complexes in 100 ns simulation. BC010 ((7S,11S,12S,14R)-4',14-dimethoxyamentol) from brown algae Cystophora fibrosa could be considered as a potential drug candidate to suppress obesity by inhibiting pancreatic lipase. Communicated by Ramaswamy H. Sarma
title: The cold face of battle – some remarks on the function of Roman helmets with face masks
Creators: name: Narloch, Krzysztof
Publisher: name: University Library Heidelberg
Year: 2015

description: Dieser Aufsatz stellt einige Überlegungen zur Funktion der römischen Helme mit Gesichtsmaske an. Diese Stücke waren einer der wirkungsvollsten Ausrüstungsgegenstände der römischen Soldaten, die seit dem 19. Jahrhundert für gelehrtes Interesse und kontroverse Debatten sorgten. Trotz überreicher Literatur ist ihre Funktion immer noch Thema zahlreicher Diskussionen. Der Gelehrtenstreit dreht sich immer wieder um einige wenige Interpretationsmöglichkeiten, wovon sich die beiden populärsten gegenseitig ausschließen: Sie postulieren, dass diese Helme entweder bei Paraden und Festlichkeiten oder in der Schlacht getragen wurden. Unter Einbeziehung der archäologischen und historischen Quellen, von Metallanalysen und der Ergebnisse verschiedener Experimente kommt der Autor zu dem Schluss, dass diese Helme für beide Gelegenheiten gleich gut geeignet waren.
description: This essay offers reflections on the functions of Roman helmets with masks. They were one of the most effective elements of Roman soldiers’ equipment, arousing scholars’ interest and controversy since the 19th century. Despite abundant literature, their function is still the subject of numerous discussions. Scholars’ views revolve around a few possibilities. Two most popular of such theses supposedly exclude one another. They claim that the helmets were used during parades and festivities or during battles. The author, taking into consideration archaeological sources, historical records, metallographic analyses and the outcome of various experiments seeks to show that these helmets proved to be a perfect solution in both cases.
Mesoscopic theory for fluctuating active nematics
Creators: name: Bertin, Eric
name: Chaté, Hugues
name: Ginelli, Francesco
name: Mishra, Shradha
name: Peshkov, Anton
name: Ramaswamy, Sriram
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: The term active nematics designates systems in which apolar elongated particles spend energy to move randomly along their axis and interact by inelastic collisions in the presence of noise. Starting from a simple Vicsek-style model for active nematics, we derive a mesoscopic theory, complete with effective multiplicative noise terms, using a combination of kinetic theory and Itô calculus approaches. The stochastic partial differential equations thus obtained are shown to recover the key terms argued in EPL \textbf{62} (2003) 196 to be at the origin of anomalous number fluctuations and long-range correlations. Their deterministic part is studied analytically, and is shown to give rise to the long-wavelength instability at onset of nematic order (see arXiv:1011.5408). The corresponding nonlinear density-segregated band solution is given in a closed form.
description: 24 pages, 1 figure, submitted to New. J. Phys
Памятники правобережья и Левобережья Днепра. Междуречье Тетерева – Роси
Creators: name: Кучера, Михайло
name: Беляева, С.
name: Блажевич, Н.
name: Горишний, П.
Publisher: name: figshare
Year: 2022
Subjects: Archaeology

description: Кучера, М. П., Беляева, С. А., Блажевич, Н. В., Горишний, П. А. 1984. Памятники правобережья и Левобережья Днепра. Междуречье Тетерева – Роси. В: Баран, В. Д. (отв. ред.). Древнерусские поселения Среднего Поднепровья (археологическая карта). Киев: Наукова думка, с. 38–92.
EasyTime++: A case study of incremental domain-specific language development
Creators: name: Fister, Iztok
name: Kosar, Tomaž
name: Fister, Iztok
name: Mernik, Marjan
Publisher: name: arXiv
Year: 2013
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: EasyTime is a domain-specific language (DSL) for measuring time during sports competitions. A distinguishing feature of DSLs is that they are much more amenable to change, and EasyTime is no exception in this regard. This paper introduces two new EasyTime features: classifications of competitors into categories, and the inclusion of competitions where the number of laps must be dynamically determined. It shows how such extensions can be incrementally added into the base-language reusing most of the language specifications. Two case studies are presented showing the suitability of this approach.
Structure-guided pharmacophore based virtual screening, docking, and molecular dynamics to discover repurposed drugs as novel inhibitors against endoribonuclease Nsp15 of SARS-CoV-2
Creators: name: Jha, Prakash
name: Saluja, Daman
name: Chopra, Madhu
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 60506 Virology

description: COVID-19 (Corona Virus Disease of 2019) caused by the novel ‘Severe Acute Respiratory Syndrome Coronavirus-2’ (SARS-CoV-2) has wreaked havoc on human health and the global economy. As a result, for new medication development, it's critical to investigate possible therapeutic targets against the novel virus. ‘Non-structural protein 15’ (Nsp15) endonuclease is one of the crucial targets which helps in the replication of virus and virulence in the host immune system. Here, in the current study, we developed the structure-based pharmacophore model based on Nsp15-UMP interactions and virtually screened several databases against the selected model. To validate the screening process, we docked the top hits obtained after secondary filtering (Lipinski’s rule of five, ADMET & Topkat) followed by 100 ns molecular dynamics (MD) simulations. Next, to revalidate the MD simulation studies, we have calculated the binding free energy of each complex using the MM-PBSA procedure. The discovered repurposed drugs can aid the rational design of novel inhibitors for Nsp15 of the SARS-CoV-2 enzyme and may be considered for immediate drug development. Communicated by Ramaswamy H. Sarma
An Exact Path-Loss Density Model for Mobiles in a Cellular System
Creators: name: Abdulla, Mouhamed
name: Shayan, Yousef R.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: In trying to emulate the spatial position of wireless nodes for purpose of analysis, we rely on stochastic simulation. And, it is customary, for mobile systems, to consider a base-station radiation coverage by an ideal cell shape. For cellular analysis, a hexagon contour is always preferred mainly because of its tessellating nature. Despite this fact, largely due to its intrinsic simplicity, in literature only random dispersion model for a circular shape is known. However, if considered, this will result an unfair nodes density specifically at the edges of non-circular contours. As a result, in this paper, we showed the exact random number generation technique required for nodes scattering inside a hexagon. Next, motivated from a system channel perspective, we argued the need for the exhaustive random mobile dropping process, and hence derived a generic close-form expression for the path-loss distribution density between a base-station and a mobile. Last, simulation was used to reaffirm the validity of the theoretical analysis using values from the new IEEE 802.20 standard.
description: Proc. of the 7th ACM International Symposium on Mobility Management and Wireless Access (MobiWac'09), held in conjunction with MSWiM'09